From 25697e5a6fa74dff5741d7a3b7b7689702551297 Mon Sep 17 00:00:00 2001 From: Carlo Fisicaro Date: Fri, 27 May 2022 12:30:08 +0200 Subject: [PATCH 1/3] feat: remove esm module --- esm/.flake8 | 10 - esm/.git-blame-ignore-revs | 2 - esm/.github/ISSUE_TEMPLATE/bug.md | 27 - esm/.gitignore | 29 - esm/CODE_OF_CONDUCT.rst | 6 - esm/CONTRIBUTING.md | 31 - esm/LICENSE | 21 - esm/README.md | 442 - esm/esm/__init__.py | 9 - esm/esm/axial_attention.py | 268 - esm/esm/constants.py | 10 - esm/esm/data.py | 495 - esm/esm/model.py | 437 - esm/esm/modules.py | 436 - esm/esm/multihead_attention.py | 523 - esm/esm/pretrained.py | 292 - esm/esm/version.py | 6 - esm/examples/1a3a_1_A.a3m | 2048 - esm/examples/1xcr_1_A.a3m | 1176 - esm/examples/5ahw_1_A.a3m | 2048 - esm/examples/P62593.fasta | 10794 - esm/examples/README.md | 10 - esm/examples/UniRef50_E9K9Y4.a3m | 34 - esm/examples/UniRef50_UPI0003108055.a3m | 2078 - esm/examples/UniRef50_UPI0003674933.a3m | 2130 - esm/examples/contact_prediction.ipynb | 290 - esm/examples/esm_structural_dataset.ipynb | 332 - esm/examples/few_proteins.fasta | 6 - .../hhblits_uniclust_2017_10_1a3a_1_A.a3m | 2606 - .../hhblits_uniclust_2017_10_1xcr_1_A.a3m | 502 - .../hhblits_uniclust_2017_10_5ahw_1_A.a3m | 3262 - esm/examples/some_proteins.fasta | 30 - esm/examples/sup_variant_prediction.ipynb | 487 - esm/extract.py | 146 - esm/hubconf.py | 14 - esm/pyproject.toml | 12 - esm/setup.py | 27 - esm/tests/test_alphabet.py | 60 - esm/tests/test_load_all.py | 51 - esm/tests/test_notebooks.py | 65 - esm/tests/test_readme.py | 182 - esm/variant-prediction/README.md | 31 - esm/variant-prediction/__init__.py | 0 .../examples/BLAT_ECOLX_1_b0.5.a3m | 153366 --------------- .../examples/BLAT_ECOLX_Ranganathan2015.csv | 4997 - .../BLAT_ECOLX_Ranganathan2015_labeled.csv | 4997 - ...T_ECOLX_Ranganathan2015_labeled_masked.csv | 4997 - esm/variant-prediction/predict.py | 249 - 48 files changed, 200071 deletions(-) delete mode 100644 esm/.flake8 delete mode 100644 esm/.git-blame-ignore-revs delete mode 100644 esm/.github/ISSUE_TEMPLATE/bug.md delete mode 100644 esm/.gitignore delete mode 100644 esm/CODE_OF_CONDUCT.rst delete mode 100644 esm/CONTRIBUTING.md delete mode 100644 esm/LICENSE delete mode 100644 esm/README.md delete mode 100644 esm/esm/__init__.py delete mode 100644 esm/esm/axial_attention.py delete mode 100644 esm/esm/constants.py delete mode 100644 esm/esm/data.py delete mode 100644 esm/esm/model.py delete mode 100644 esm/esm/modules.py delete mode 100644 esm/esm/multihead_attention.py delete mode 100644 esm/esm/pretrained.py delete mode 100644 esm/esm/version.py delete mode 100644 esm/examples/1a3a_1_A.a3m delete mode 100644 esm/examples/1xcr_1_A.a3m delete mode 100644 esm/examples/5ahw_1_A.a3m delete mode 100644 esm/examples/P62593.fasta delete mode 100644 esm/examples/README.md delete mode 100644 esm/examples/UniRef50_E9K9Y4.a3m delete mode 100644 esm/examples/UniRef50_UPI0003108055.a3m delete mode 100644 esm/examples/UniRef50_UPI0003674933.a3m delete mode 100644 esm/examples/contact_prediction.ipynb delete mode 100644 esm/examples/esm_structural_dataset.ipynb delete mode 100644 esm/examples/few_proteins.fasta delete mode 100644 esm/examples/hhblits_uniclust_2017_10_1a3a_1_A.a3m delete mode 100644 esm/examples/hhblits_uniclust_2017_10_1xcr_1_A.a3m delete mode 100644 esm/examples/hhblits_uniclust_2017_10_5ahw_1_A.a3m delete mode 100644 esm/examples/some_proteins.fasta delete mode 100644 esm/examples/sup_variant_prediction.ipynb delete mode 100644 esm/extract.py delete mode 100644 esm/hubconf.py delete mode 100644 esm/pyproject.toml delete mode 100644 esm/setup.py delete mode 100644 esm/tests/test_alphabet.py delete mode 100644 esm/tests/test_load_all.py delete mode 100644 esm/tests/test_notebooks.py delete mode 100644 esm/tests/test_readme.py delete mode 100644 esm/variant-prediction/README.md delete mode 100644 esm/variant-prediction/__init__.py delete mode 100644 esm/variant-prediction/examples/BLAT_ECOLX_1_b0.5.a3m delete mode 100644 esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv delete mode 100644 esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv delete mode 100644 esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled_masked.csv delete mode 100644 esm/variant-prediction/predict.py diff --git a/esm/.flake8 b/esm/.flake8 deleted file mode 100644 index fa3edf2..0000000 --- a/esm/.flake8 +++ /dev/null @@ -1,10 +0,0 @@ -[flake8] -max-line-length = 99 -ignore = E203,W503 -exclude = - .git, - __pycache__, - build, - dist, - experimental - third_party diff --git a/esm/.git-blame-ignore-revs b/esm/.git-blame-ignore-revs deleted file mode 100644 index b9a5aa4..0000000 --- a/esm/.git-blame-ignore-revs +++ /dev/null @@ -1,2 +0,0 @@ -# Migrate code style to Black -8bc7e948cd9bf0b6d1f2113e221ef548ef663377 diff --git a/esm/.github/ISSUE_TEMPLATE/bug.md b/esm/.github/ISSUE_TEMPLATE/bug.md deleted file mode 100644 index 14e5b65..0000000 --- a/esm/.github/ISSUE_TEMPLATE/bug.md +++ /dev/null @@ -1,27 +0,0 @@ ---- -name: "[Bug Report]" -about: "Create a bug report. For other questions: see Discussions tab." - ---- - -NOTE: if this is not a bug report, please use the [GitHub Discussions](https://github.com/facebookresearch/esm/discussions) for support questions (How do I do X?), feature requests, ideas, showcasing new applications, etc. - - -**Bug description** -Please enter a clear and concise description of what the bug is. - -**Reproduction steps** -Enter steps to reproduce the behavior. - -**Expected behavior** -Give a clear and concise description of what you expected to happen. - -**Logs** -Please paste the command line output: - -``` -Output goes here -``` - -**Additional context** -Add any other context about the problem here. (like proxy settings, network setup, overall goals, etc.) diff --git a/esm/.gitignore b/esm/.gitignore deleted file mode 100644 index 0a07698..0000000 --- a/esm/.gitignore +++ /dev/null @@ -1,29 +0,0 @@ -# tensor dumps -*.pt -# Compiler Output # -################### -*.py[cod] -*.so -*.o -*.exe -*.class - -# Folders # -########### -bin/ -build/ -dist/ -local/ -tmp/ -__pycache__/ -*.egg-info/ -.ipynb_checkpoints/ -.vscode/ - -# Junk # -######## -.DS_Store* -.*.swp -*.swp -*.log -*~ diff --git a/esm/CODE_OF_CONDUCT.rst b/esm/CODE_OF_CONDUCT.rst deleted file mode 100644 index f7367ec..0000000 --- a/esm/CODE_OF_CONDUCT.rst +++ /dev/null @@ -1,6 +0,0 @@ -Code of Conduct -=============== - -Facebook has adopted a Code of Conduct that we expect project participants to adhere to. Please `read the full text`__ so that you can understand what actions will and will not be tolerated. - -__ https://code.facebook.com/codeofconduct diff --git a/esm/CONTRIBUTING.md b/esm/CONTRIBUTING.md deleted file mode 100644 index 9d6a6cc..0000000 --- a/esm/CONTRIBUTING.md +++ /dev/null @@ -1,31 +0,0 @@ -# Contributing to esm -We want to make contributing to this project as easy and transparent as -possible. - -## Pull Requests -We actively welcome your pull requests. - -1. Fork the repo and create your branch from `master`. -2. If you've added code that should be tested, add tests. -3. If you've changed APIs, update the documentation. -4. Ensure the test suite passes. -5. Make sure your code lints. -6. If you haven't already, complete the Contributor License Agreement ("CLA"). - -## Contributor License Agreement ("CLA") -In order to accept your pull request, we need you to submit a CLA. You only need -to do this once to work on any of Facebook's open source projects. - -Complete your CLA here: - -## Issues -We use GitHub issues to track public bugs. Please ensure your description is -clear and has sufficient instructions to be able to reproduce the issue. - -Facebook has a [bounty program](https://www.facebook.com/whitehat/) for the safe -disclosure of security bugs. In those cases, please go through the process -outlined on that page and do not file a public issue. - -## License -By contributing to icp-block-mdp, you agree that your contributions will be licensed -under the LICENSE file in the root directory of this source tree. diff --git a/esm/LICENSE b/esm/LICENSE deleted file mode 100644 index b96dcb0..0000000 --- a/esm/LICENSE +++ /dev/null @@ -1,21 +0,0 @@ -MIT License - -Copyright (c) Facebook, Inc. and its affiliates. - -Permission is hereby granted, free of charge, to any person obtaining a copy -of this software and associated documentation files (the "Software"), to deal -in the Software without restriction, including without limitation the rights -to use, copy, modify, merge, publish, distribute, sublicense, and/or sell -copies of the Software, and to permit persons to whom the Software is -furnished to do so, subject to the following conditions: - -The above copyright notice and this permission notice shall be included in all -copies or substantial portions of the Software. - -THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR -IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, -FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE -AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER -LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, -OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE -SOFTWARE. diff --git a/esm/README.md b/esm/README.md deleted file mode 100644 index 23f6110..0000000 --- a/esm/README.md +++ /dev/null @@ -1,442 +0,0 @@ -# Evolutionary Scale Modeling - - -This repository contains code and pre-trained weights for **Transformer protein language models** from Facebook AI Research, including our state-of-the-art **ESM-1b** and **MSA Transformer**. -Transformer protein language models were introduced in our paper, ["Biological structure and function emerge from scaling unsupervised learning to 250 million protein sequences" (Rives et al., 2019)](https://doi.org/10.1101/622803). - -**ESM-1b outperforms all tested single-sequence protein language models across a range of structure prediction tasks.** -The MSA Transformer (ESM-MSA-1) can improve performance further by leveraging MSA information. - -
Citation - -```bibtex -@article{rives2019biological, - author={Rives, Alexander and Meier, Joshua and Sercu, Tom and Goyal, Siddharth and Lin, Zeming and Liu, Jason and Guo, Demi and Ott, Myle and Zitnick, C. Lawrence and Ma, Jerry and Fergus, Rob}, - title={Biological Structure and Function Emerge from Scaling Unsupervised Learning to 250 Million Protein Sequences}, - year={2019}, - doi={10.1101/622803}, - url={https://www.biorxiv.org/content/10.1101/622803v4}, - journal={bioRxiv} -} -``` -
- -
Table of contents - -- [Main models you should use](#main-models) -- [Comparison to related works](#perf_related) -- [Usage](#usage) - - [Quick Start](#quickstart) - - [Compute embeddings in bulk from FASTA](#bulk_fasta) - - [Zero-shot variant prediction](#zs_variant) - - [Notebooks](#notebooks) -- [Available Models and Datasets](#available) - - [Pre-trained Models](#available-models) - - [ESM Structural Split Dataset](#available-esmssd) - - [Pre-training Dataset Split](#available-pretraining-split) -- [Citations](#citations) -- [License](#license) -
- -
What's New - -- August 2021: Added flexibility to tokenizer to allow for spaces and special tokens (like ``) in sequence. -- July 2021: New pre-trained model ESM-1v released, trained on UniRef90 (see [Meier et al. 2021](https://www.biorxiv.org/content/10.1101/2021.07.09.450648v1)). -- July 2021: New MSA Transformer released, with a minor fix in the row positional embeddings (`ESM-MSA-1b`). -- Feb 2021: MSA Transformer added (see [Rao et al. 2021](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1)). Example usage in [notebook](#notebooks). -- Dec 2020: [Self-Attention Contacts](#notebooks) for all pre-trained models (see [Rao et al. 2020](https://doi.org/10.1101/2020.12.15.422761)) -- Dec 2020: Added new pre-trained model [ESM-1b](#perf_related) (see [Rives et al. 2019](https://doi.org/10.1101/622803) Appendix B) -- Dec 2020: [ESM Structural Split Dataset](#available-esmssd) (see [Rives et al. 2019](https://doi.org/10.1101/622803) Appendix A.10) - -
- -## Main models you should use - -| Shorthand | `esm.pretrained.` | Dataset | Description | -|-----------|-----------------------------|---------|--------------| -| ESM-1b | `esm1b_t33_650M_UR50S()` | UR50 | SOTA general-purpose protein language model. Can be used to predict structure, function and other protein properties directly from individual sequences. Released with [Rives et al. 2019](https://doi.org/10.1101/622803) (Dec 2020 update). | -| ESM-MSA-1b| `esm_msa1b_t12_100M_UR50S()` | UR50 + MSA | MSA Transformer language model. Can be used to extract embeddings from an MSA. Enables SOTA inference of structure. Released with [Rao et al. 2021](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v2) (ICML'21 version, June 2021). | -| ESM-1v | `esm1v_t33_650M_UR90S_1()` ... `esm1v_t33_650M_UR90S_5()`| UR90 | Language model specialized for prediction of variant effects. Enables SOTA zero-shot prediction of the functional effects of sequence variations. Same architecture as ESM-1b, but trained on UniRef90. Released with [Meier et al. 2021](https://www.biorxiv.org/content/10.1101/2021.07.09.450648v1). | - -For a complete list of available models, with details and release notes, see [Pre-trained Models](#available-models). - -## Comparison to related works - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
TaskUnsupervised contact predictionSupervised contact predictionSSP
Test setLarge validCASP13-FMCAMEOCASP13-FMCAMEOCB513
Gremlin (Potts)39.316.924.040.147.3
UniRep11.217.858.4
SeqVec13.822.562.1
TAPE11.25.56.812.315.958.0
ProtBert-BFD34.113.523.924.737.070.0
Prot-T5-XL-BFD35.616.525.925.040.871.4 ± 0.3
ESM-133.713.621.4(todo)(todo)69.2
ESM-1b41.117.030.928.244.471.6 ± 0.1
ESM-1v35.314.224.4
ESM-MSA-1b57.444.843.554.655.873.4 ± 0.3
- -Comparison to related protein language models on structure prediction tasks. - -* All contact numbers are the top-L,LR precision metric, where long range means sequence separation of at least 24 residues -* For unsupervised contact prediction, a sparse linear combination of the attention heads is used to directly predict protein contacts, -fitted with logistic regression on 20 structures. -For more details on the method, see [Rao et al. 2020](https://doi.org/10.1101/2020.12.15.422761). -* Supervised contact prediction all uses the same resnet (32 layers) and trRosetta training data, cf [Rao et al. 2021](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v2). -* (SSP) Secondary structure Q8 accuracy on CB513, transformer finetuned with convolution + LSTM head. -* Direct coupling analysis methods (Gremlin, mfDCA, Psicov) and ESM-MSA-1 use the [trRosetta MSAs](https://yanglab.nankai.edu.cn/trRosetta/benchmark/), while other methods predict from single sequence. - - -## Usage - -### Quick Start - -As a prerequisite, you must have PyTorch 1.5 or later installed to use this repository. - -You can use this one-liner for installation: - -```bash -$ pip install fair-esm -``` - -We also support PyTorch Hub, which removes the need to clone and/or install this repository yourself: - -```python -import torch -model, alphabet = torch.hub.load("facebookresearch/esm:main", "esm1b_t33_650M_UR50S") -``` - -Then, you can load and use a pretrained model as follows: - -```python -import torch -import esm - -# Load ESM-1b model -model, alphabet = esm.pretrained.esm1b_t33_650M_UR50S() -batch_converter = alphabet.get_batch_converter() - -# Prepare data (first 2 sequences from ESMStructuralSplitDataset superfamily / 4) -data = [ - ("protein1", "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG"), - ("protein2", "KALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), - ("protein2 with mask","KALTARQQEVFDLIRDISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE"), - ("protein3", "K A I S Q"), -] -batch_labels, batch_strs, batch_tokens = batch_converter(data) - -# Extract per-residue representations (on CPU) -with torch.no_grad(): - results = model(batch_tokens, repr_layers=[33], return_contacts=True) -token_representations = results["representations"][33] - -# Generate per-sequence representations via averaging -# NOTE: token 0 is always a beginning-of-sequence token, so the first residue is token 1. -sequence_representations = [] -for i, (_, seq) in enumerate(data): - sequence_representations.append(token_representations[i, 1 : len(seq) + 1].mean(0)) - -# Look at the unsupervised self-attention map contact predictions -import matplotlib.pyplot as plt -for (_, seq), attention_contacts in zip(data, results["contacts"]): - plt.matshow(attention_contacts[: len(seq), : len(seq)]) - plt.title(seq) - plt.show() -``` - -### Compute embeddings in bulk from FASTA - -We provide a script that efficiently extracts embeddings in bulk from a FASTA file. -A cuda device is optional and will be auto-detected. -The following command extracts the final-layer embedding for a FASTA file from the ESM-1b model: - -```bash -$ python extract.py esm1b_t33_650M_UR50S examples/some_proteins.fasta examples/some_proteins_emb_esm1b/ \ - --repr_layers 0 32 33 --include mean per_tok -``` - -Directory `examples/some_proteins_emb_esm1b/` now contains one `.pt` file per FASTA sequence; use `torch.load()` to load them. -`extract.py` has flags that determine what's included in the `.pt` file: -* `--repr-layers` (default: final only) selects which layers to include embeddings from. -* `--include` specifies what embeddings to save. You can use the following: - * `per_tok` includes the full sequence, with an embedding per amino acid (seq_len x hidden_dim). - * `mean` includes the embeddings averaged over the full sequence, per layer. - * `bos` includes the embeddings from the beginning-of-sequence token. - (NOTE: Don't use with the pre-trained models - we trained without bos-token supervision) - -### Zero-shot variant prediction -See "[./variant-prediction/](variant-prediction/)" for code and pre-trained weights for the ESM-1v models described in -[Language models enable zero-shot prediction of the effects of mutations on protein function. (Meier et al. 2021)](https://www.biorxiv.org/content/10.1101/2021.07.09.450648v1). - - -### Notebooks - -#### Supervised variant prediction - training a classifier on the embeddings - -[](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/sup_variant_prediction.ipynb) - - -To help you get started with using the embeddings, this [jupyter notebook tutorial](examples/sup_variant_prediction.ipynb) shows how to train a supervised variant predictor using embeddings from ESM-1. -You can adopt a similar protocol to train a model for any downstream task, even with limited data. -First you can obtain the embeddings for ``examples/P62593.fasta`` either by [downloading the precomputed](https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz) embeddings -as instructed in the notebook or by running the following: - -```bash -# Obtain the embeddings -$ python extract.py esm1_t34_670M_UR50S examples/P62593.fasta examples/P62593_reprs/ \ - --repr_layers 34 --include mean -``` - -Then, follow the remaining instructions in the tutorial. You can also run the tutorial in a [colab notebook](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/variant_prediction.ipynb). - -**Note this is somewhat outdated: use `esm1v_t33_650M_UR90S` instead, and -see [the newer instructions for zero-shot variant prediction](variant-prediction/), -that is without any supervised training.** - - -#### Unsupervised contact prediction -[](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/contact_prediction.ipynb) - -This [jupyter notebook tutorial](examples/contact_prediction.ipynb) demonstrates contact prediction with both the ESM-1b and MSA Transformer (ESM-MSA-1) models. -Contact prediction is based on a logistic regression over the model's attention maps. -This methodology is based on our ICLR 2021 paper, -[Transformer protein language models are unsupervised structure learners. (Rao et al. 2020)](https://doi.org/10.1101/2020.12.15.422761) -The MSA Transformer (ESM-MSA-1) takes a multiple sequence alignment (MSA) as input, and uses the tied row self-attention maps in the same way. -See [MSA Transformer. (Rao et al. 2021)](https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1). - -To get unsupervised attention-based contacts, call `model.predict_contacts(tokens)` or `model(tokens, return_contacts=True)`. - - -#### ESMStructuralSplitDataset and self-attention contact prediction -[](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/esm_structural_dataset.ipynb) - -And this [jupyter notebook tutorial](examples/esm_structural_dataset.ipynb) shows how to load and index the `ESMStructuralSplitDataset`, -and computes the self-attention map unsupervised contact predictions using ESM-1b. - - -## Available Models and Datasets - -### Pre-trained Models - -| Shorthand | `esm.pretrained.` | #layers | #params | Dataset | Embedding Dim | Model URL (automatically downloaded to `~/.cache/torch/hub/checkpoints`) | -|-----------|---------------------|---------|---------|---------|---------------|-----------------------------------------------------------------------| -| ESM-1v | `esm1v_t33_650M_UR90S_[1-5]` | 33 | 650M | UR90/S 2020_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1v_t33_650M_UR90S_1.pt | -| ESM-MSA-1b| `esm_msa1b_t12_100M_UR50S` | 12 | 100M | UR50/S + MSA 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm_msa1b_t12_100M_UR50S.pt | -| ESM-MSA-1 | `esm_msa1_t12_100M_UR50S` | 12 | 100M | UR50/S + MSA 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm_msa1_t12_100M_UR50S.pt | -| ESM-1b | `esm1b_t33_650M_UR50S` | 33 | 650M | UR50/S 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1b_t33_650M_UR50S.pt | -| ESM-1 | `esm1_t34_670M_UR50S` | 34 | 670M | UR50/S 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t34_670M_UR50S.pt | -| | `esm1_t34_670M_UR50D` | 34 | 670M | UR50/D 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t34_670M_UR50D.pt | -| | `esm1_t34_670M_UR100` | 34 | 670M | UR100 2018_03 | 1280 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t34_670M_UR100.pt | -| | `esm1_t12_85M_UR50S` | 12 | 85M | UR50/S 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t12_85M_UR50S.pt | -| | `esm1_t6_43M_UR50S` | 6 | 43M | UR50/S 2018_03 | 768 | https://dl.fbaipublicfiles.com/fair-esm/models/esm1_t6_43M_UR50S.pt | - - -Here is a chronological list of the released models and the paper they were introduced in: - -| Shorthand | Release Notes | -|-----------|---------------| -| ESM-1 | Released with Rives et al. 2019 (Aug 2020 update). | -| ESM-1b | Released with Rives et al. 2019 (Dec 2020 update). See Appendix B. | -| ESM-MSA-1 | Released with Rao et al. 2021 (Preprint v1). | -| ESM-MSA-1b | Released with Rao et al. 2021 (ICML'21 version, June 2021). | -| ESM-1v | Released with Meier et al. 2021. | - -### ESM Structural Split Dataset -This is a five-fold cross validation dataset of protein domain structures that can be used to measure generalization of representations -across different levels of structural dissimilarity. -The dataset implements structural holdouts at the family, superfamily, and fold -level. The SCOPe database is used to classify domains. Independently for each level of structural hold-out, -the domains are split into 5 equal sets, i.e. five sets of folds, superfamilies, or families. This ensures -that for each of the five partitions, structures having the same classification do not appear in both the -train and test sets. For a given classification level each structure appears in a test set once, so that -in the cross validation experiment each of the structures will be evaluated exactly once. - -The dataset provides 3d coordinates, distance maps, and secondary structure labels. -For further details on the construction of the dataset -see [Rives et al. 2019](https://doi.org/10.1101/622803) Appendix A.10. - -This [jupyter notebook tutorial](examples/esm_structural_dataset.ipynb) shows how to load and index the `ESMStructuralSplitDataset`. - -`ESMStructuralSplitDataset`, upon initializing, will download `splits` and `pkl`. -We also provide `msas` for each of the domains. The data can be directly downloaded below. - -| Name | Description | URL | -|--------|-------------------------------------------------------------------------------|-----------------------------------------------------------------------| -| splits | train/valid splits | https://dl.fbaipublicfiles.com/fair-esm/structural-data/splits.tar.gz | -| pkl | pkl objects containing sequence, SSP labels, distance map, and 3d coordinates | https://dl.fbaipublicfiles.com/fair-esm/structural-data/pkl.tar.gz | -| msas | a3m files containing MSA for each domain | https://dl.fbaipublicfiles.com/fair-esm/structural-data/msas.tar.gz | - -### Pre-training Dataset Split -The split files establishing which UniRef50 clusters were used as held-out evaluation set for pre-training -in [Rives et al. 2019](https://doi.org/10.1101/622803) and [Rao et al. 2021](https://doi.org/10.1101/2021.02.12.430858) can be found here: -* [UniRef50 IDs of evaluation set](https://dl.fbaipublicfiles.com/fair-esm/pretraining-data/uniref201803_ur50_valid_headers.txt.gz): 3.016 M clusters -* [UniRef100 IDs of evaluation set](https://dl.fbaipublicfiles.com/fair-esm/pretraining-data/uniref201803_ur100_valid_headers.txt.gz): 13.745 M proteins, expanding the same UniRef50 clusters. - -These files only contain only the UniRef50 IDs and UniRef100 IDs corresponding to the [UniRef database, 2018-03 release](https://ftp.uniprot.org/pub/databases/uniprot/previous_releases/release-2018_03/uniref/) -which is released by the UniProt Consortium under a [Creative Commons Attribution (CC BY 4.0) License](https://www.uniprot.org/help/license). - -## Citations - -If you find the models useful in your research, we ask that you cite the relevant paper: - -```bibtex -@article{rives2019biological, - author={Rives, Alexander and Meier, Joshua and Sercu, Tom and Goyal, Siddharth and Lin, Zeming and Liu, Jason and Guo, Demi and Ott, Myle and Zitnick, C. Lawrence and Ma, Jerry and Fergus, Rob}, - title={Biological Structure and Function Emerge from Scaling Unsupervised Learning to 250 Million Protein Sequences}, - year={2019}, - doi={10.1101/622803}, - url={https://www.biorxiv.org/content/10.1101/622803v4}, - journal={bioRxiv} -} -``` - -For the self-attention contact prediction: - -```bibtex -@article{rao2020transformer, - author = {Rao, Roshan M and Meier, Joshua and Sercu, Tom and Ovchinnikov, Sergey and Rives, Alexander}, - title={Transformer protein language models are unsupervised structure learners}, - year={2020}, - doi={10.1101/2020.12.15.422761}, - url={https://www.biorxiv.org/content/10.1101/2020.12.15.422761v1}, - journal={bioRxiv} -} -``` - -For the MSA Transformer: - -```bibtex -@article{rao2021msa, - author = {Rao, Roshan and Liu, Jason and Verkuil, Robert and Meier, Joshua and Canny, John F. and Abbeel, Pieter and Sercu, Tom and Rives, Alexander}, - title={MSA Transformer}, - year={2021}, - doi={10.1101/2021.02.12.430858}, - url={https://www.biorxiv.org/content/10.1101/2021.02.12.430858v1}, - journal={bioRxiv} -} -``` - -For variant prediction using ESM-1v: - -```bibtex -@article{meier2021language, - author = {Meier, Joshua and Rao, Roshan and Verkuil, Robert and Liu, Jason and Sercu, Tom and Rives, Alexander}, - title = {Language models enable zero-shot prediction of the effects of mutations on protein function}, - year={2021}, - doi={10.1101/2021.07.09.450648}, - url={https://www.biorxiv.org/content/10.1101/2021.07.09.450648v1}, - journal={bioRxiv} -} -``` - -Much of this code builds on the [fairseq](https://github.com/pytorch/fairseq) sequence modeling framework. We use fairseq internally for our protein language modeling research. We highly recommend trying it out if you'd like to pre-train protein language models from scratch. - -## License - -This source code is licensed under the MIT license found in the `LICENSE` file -in the root directory of this source tree. diff --git a/esm/esm/__init__.py b/esm/esm/__init__.py deleted file mode 100644 index 1b880c8..0000000 --- a/esm/esm/__init__.py +++ /dev/null @@ -1,9 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -from . import pretrained # noqa -from .data import Alphabet, BatchConverter, FastaBatchedDataset # noqa -from .model import MSATransformer, ProteinBertModel # noqa -from .version import version as __version__ # noqa diff --git a/esm/esm/axial_attention.py b/esm/esm/axial_attention.py deleted file mode 100644 index 677869e..0000000 --- a/esm/esm/axial_attention.py +++ /dev/null @@ -1,268 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import math - -import torch -import torch.nn as nn - - -class RowSelfAttention(nn.Module): - """Compute self-attention over rows of a 2D input.""" - - def __init__( - self, - embed_dim, - num_heads, - dropout=0.0, - max_tokens_per_msa: int = 2 ** 16, - ): - super().__init__() - self.num_heads = num_heads - self.dropout = dropout - self.head_dim = embed_dim // num_heads - self.scaling = self.head_dim ** -0.5 - self.max_tokens_per_msa = max_tokens_per_msa - self.attn_shape = "hnij" - - self.k_proj = nn.Linear(embed_dim, embed_dim) - self.v_proj = nn.Linear(embed_dim, embed_dim) - self.q_proj = nn.Linear(embed_dim, embed_dim) - - self.out_proj = nn.Linear(embed_dim, embed_dim) - self.dropout_module = nn.Dropout(dropout) - - def align_scaling(self, q): - num_rows = q.size(0) - return self.scaling / math.sqrt(num_rows) - - def _batched_forward( - self, - x, - self_attn_mask=None, - self_attn_padding_mask=None, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - max_rows = max(1, self.max_tokens_per_msa // num_cols) - attns = 0 - scaling = self.align_scaling(x) - for start in range(0, num_rows, max_rows): - attn_weights = self.compute_attention_weights( - x[start : start + max_rows], - scaling, - self_attn_mask=self_attn_mask, - self_attn_padding_mask=self_attn_padding_mask[ - :, start : start + max_rows - ] - if self_attn_padding_mask is not None - else None, - ) - attns += attn_weights - attn_probs = attns.softmax(-1) - attn_probs = self.dropout_module(attn_probs) - - outputs = [] - for start in range(0, num_rows, max_rows): - output = self.compute_attention_update( - x[start : start + max_rows], attn_probs - ) - outputs.append(output) - - output = torch.cat(outputs, 0) - return output, attn_probs - - def compute_attention_weights( - self, - x, - scaling: float, - self_attn_mask=None, - self_attn_padding_mask=None, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - q = self.q_proj(x).view( - num_rows, num_cols, batch_size, self.num_heads, self.head_dim - ) - k = self.k_proj(x).view( - num_rows, num_cols, batch_size, self.num_heads, self.head_dim - ) - q *= scaling - if self_attn_padding_mask is not None: - # Zero out any padded aligned positions - this is important since - # we take a sum across the alignment axis. - q *= 1 - self_attn_padding_mask.permute(1, 2, 0).unsqueeze(3).unsqueeze( - 4 - ).to(q) - - attn_weights = torch.einsum(f"rinhd,rjnhd->{self.attn_shape}", q, k) - - if self_attn_mask is not None: - raise NotImplementedError - # Mask Size: [B x R x C], Weights Size: [H x B x C x C] - - if self_attn_padding_mask is not None: - attn_weights = attn_weights.masked_fill( - self_attn_padding_mask[:, 0].unsqueeze(0).unsqueeze(2), - -10000, - ) - - return attn_weights - - def compute_attention_update( - self, - x, - attn_probs, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - v = self.v_proj(x).view( - num_rows, num_cols, batch_size, self.num_heads, self.head_dim - ) - context = torch.einsum(f"{self.attn_shape},rjnhd->rinhd", attn_probs, v) - context = context.contiguous().view(num_rows, num_cols, batch_size, embed_dim) - output = self.out_proj(context) - return output - - def forward( - self, - x, - self_attn_mask=None, - self_attn_padding_mask=None, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - if ( - num_rows * num_cols > self.max_tokens_per_msa - ) and not torch.is_grad_enabled(): - return self._batched_forward(x, self_attn_mask, self_attn_padding_mask) - else: - scaling = self.align_scaling(x) - attn_weights = self.compute_attention_weights( - x, scaling, self_attn_mask, self_attn_padding_mask - ) - attn_probs = attn_weights.softmax(-1) - attn_probs = self.dropout_module(attn_probs) - output = self.compute_attention_update(x, attn_probs) - return output, attn_probs - - -class ColumnSelfAttention(nn.Module): - """Compute self-attention over columns of a 2D input.""" - - def __init__( - self, - embed_dim, - num_heads, - dropout=0.0, - max_tokens_per_msa: int = 2 ** 16, - ): - super().__init__() - - self.num_heads = num_heads - self.dropout = dropout - self.head_dim = embed_dim // num_heads - self.scaling = self.head_dim ** -0.5 - self.max_tokens_per_msa = max_tokens_per_msa - - self.k_proj = nn.Linear(embed_dim, embed_dim) - self.v_proj = nn.Linear(embed_dim, embed_dim) - self.q_proj = nn.Linear(embed_dim, embed_dim) - - self.out_proj = nn.Linear(embed_dim, embed_dim) - self.dropout_module = nn.Dropout(dropout) - - def _batched_forward( - self, - x, - self_attn_mask=None, - self_attn_padding_mask=None, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - max_cols = max(1, self.max_tokens_per_msa // num_rows) - outputs = [] - attns = [] - for start in range(0, num_cols, max_cols): - output, attn = self( - x[:, start : start + max_cols], - self_attn_mask=self_attn_mask, - self_attn_padding_mask=self_attn_padding_mask[ - :, :, start : start + max_cols - ] - if self_attn_padding_mask is not None - else None, - ) - outputs.append(output) - attns.append(attn) - output = torch.cat(outputs, 1) - attns = torch.cat(attns, 1) - return output, attns - - def compute_attention_update( - self, - x, - self_attn_mask=None, - self_attn_padding_mask=None, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - if num_rows == 1: - # if there is only 1 position, this is equivalent and doesn't break with padding - attn_probs = torch.ones( - self.num_heads, - num_cols, - batch_size, - num_rows, - num_rows, - device=x.device, - dtype=x.dtype, - ) - output = self.out_proj(self.v_proj(x)) - else: - q = self.q_proj(x).view( - num_rows, num_cols, batch_size, self.num_heads, self.head_dim - ) - k = self.k_proj(x).view( - num_rows, num_cols, batch_size, self.num_heads, self.head_dim - ) - v = self.v_proj(x).view( - num_rows, num_cols, batch_size, self.num_heads, self.head_dim - ) - q *= self.scaling - - attn_weights = torch.einsum("icnhd,jcnhd->hcnij", q, k) - - if self_attn_mask is not None: - raise NotImplementedError - if self_attn_padding_mask is not None: - attn_weights = attn_weights.masked_fill( - self_attn_padding_mask.permute(2, 0, 1).unsqueeze(0).unsqueeze(3), - -10000, - ) - - attn_probs = attn_weights.softmax(-1) - attn_probs = self.dropout_module(attn_probs) - context = torch.einsum("hcnij,jcnhd->icnhd", attn_probs, v) - context = context.contiguous().view( - num_rows, num_cols, batch_size, embed_dim - ) - output = self.out_proj(context) - return output, attn_probs - - def forward( - self, - x, - self_attn_mask=None, - self_attn_padding_mask=None, - ): - num_rows, num_cols, batch_size, embed_dim = x.size() - # if False and num_rows * num_cols > 2 ** 14 and not torch.is_grad_enabled(): - if ( - num_rows * num_cols - ) > self.max_tokens_per_msa and not torch.is_grad_enabled(): - return self._batched_forward( - x, - self_attn_mask, - self_attn_padding_mask, - ) - else: - return self.compute_attention_update( - x, self_attn_mask, self_attn_padding_mask - ) diff --git a/esm/esm/constants.py b/esm/esm/constants.py deleted file mode 100644 index fc9abb1..0000000 --- a/esm/esm/constants.py +++ /dev/null @@ -1,10 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -# fmt: off -proteinseq_toks = { - 'toks': ['L', 'A', 'G', 'V', 'S', 'E', 'R', 'T', 'I', 'D', 'P', 'K', 'Q', 'N', 'F', 'Y', 'M', 'H', 'W', 'C', 'X', 'B', 'U', 'Z', 'O', '.', '-'] -} -# fmt: on diff --git a/esm/esm/data.py b/esm/esm/data.py deleted file mode 100644 index 2c7d6a8..0000000 --- a/esm/esm/data.py +++ /dev/null @@ -1,495 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import itertools -import os -import pickle -import re -import shutil -from pathlib import Path -from typing import List, Sequence, Tuple, Union - -import torch - -from .constants import proteinseq_toks - -RawMSA = Sequence[Tuple[str, str]] - - -class FastaBatchedDataset(object): - def __init__(self, sequence_labels, sequence_strs): - self.sequence_labels = list(sequence_labels) - self.sequence_strs = list(sequence_strs) - - @classmethod - def from_file(cls, fasta_file): - sequence_labels, sequence_strs = [], [] - cur_seq_label = None - buf = [] - - def _flush_current_seq(): - nonlocal cur_seq_label, buf - if cur_seq_label is None: - return - sequence_labels.append(cur_seq_label) - sequence_strs.append("".join(buf)) - cur_seq_label = None - buf = [] - - with open(fasta_file, "r") as infile: - for line_idx, line in enumerate(infile): - if line.startswith(">"): # label line - _flush_current_seq() - line = line[1:].strip() - if len(line) > 0: - cur_seq_label = line - else: - cur_seq_label = f"seqnum{line_idx:09d}" - else: # sequence line - buf.append(line.strip()) - - _flush_current_seq() - - assert len(set(sequence_labels)) == len( - sequence_labels - ), "Found duplicate sequence labels" - - return cls(sequence_labels, sequence_strs) - - def __len__(self): - return len(self.sequence_labels) - - def __getitem__(self, idx): - return self.sequence_labels[idx], self.sequence_strs[idx] - - def get_batch_indices(self, toks_per_batch, extra_toks_per_seq=0): - sizes = [(len(s), i) for i, s in enumerate(self.sequence_strs)] - sizes.sort() - batches = [] - buf = [] - max_len = 0 - - def _flush_current_buf(): - nonlocal max_len, buf - if len(buf) == 0: - return - batches.append(buf) - buf = [] - max_len = 0 - - for sz, i in sizes: - sz += extra_toks_per_seq - if max(sz, max_len) * (len(buf) + 1) > toks_per_batch: - _flush_current_buf() - max_len = max(max_len, sz) - buf.append(i) - - _flush_current_buf() - return batches - - -class Alphabet(object): - def __init__( - self, - standard_toks: Sequence[str], - prepend_toks: Sequence[str] = ("", "", "", ""), - append_toks: Sequence[str] = ("", "", ""), - prepend_bos: bool = True, - append_eos: bool = False, - use_msa: bool = False, - ): - self.standard_toks = list(standard_toks) - self.prepend_toks = list(prepend_toks) - self.append_toks = list(append_toks) - self.prepend_bos = prepend_bos - self.append_eos = append_eos - self.use_msa = use_msa - - self.all_toks = list(self.prepend_toks) - self.all_toks.extend(self.standard_toks) - for i in range((8 - (len(self.all_toks) % 8)) % 8): - self.all_toks.append(f"") - self.all_toks.extend(self.append_toks) - - self.tok_to_idx = {tok: i for i, tok in enumerate(self.all_toks)} - - self.unk_idx = self.tok_to_idx[""] - self.padding_idx = self.get_idx("") - self.cls_idx = self.get_idx("") - self.mask_idx = self.get_idx("") - self.eos_idx = self.get_idx("") - self.all_special_tokens = ["", "", "", "", ""] - self.unique_no_split_tokens = self.all_toks - - def __len__(self): - return len(self.all_toks) - - def get_idx(self, tok): - return self.tok_to_idx.get(tok, self.unk_idx) - - def get_tok(self, ind): - return self.all_toks[ind] - - def to_dict(self): - return self.tok_to_idx.copy() - - def get_batch_converter(self): - if self.use_msa: - return MSABatchConverter(self) - else: - return BatchConverter(self) - - @classmethod - def from_architecture(cls, name: str) -> "Alphabet": - if name in ("ESM-1", "protein_bert_base"): - standard_toks = proteinseq_toks["toks"] - prepend_toks: Tuple[str, ...] = ("", "", "", "") - append_toks: Tuple[str, ...] = ("", "", "") - prepend_bos = True - append_eos = False - use_msa = False - elif name in ("ESM-1b", "roberta_large"): - standard_toks = proteinseq_toks["toks"] - prepend_toks = ("", "", "", "") - append_toks = ("",) - prepend_bos = True - append_eos = True - use_msa = False - elif name in ("MSA Transformer", "msa_transformer"): - standard_toks = proteinseq_toks["toks"] - prepend_toks = ("", "", "", "") - append_toks = ("",) - prepend_bos = True - append_eos = False - use_msa = True - else: - raise ValueError("Unknown architecture selected") - return cls( - standard_toks, prepend_toks, append_toks, prepend_bos, append_eos, use_msa - ) - - def _tokenize(self, text) -> str: - return text.split() - - def tokenize(self, text, **kwargs) -> List[str]: - """ - Inspired by https://github.com/huggingface/transformers/blob/master/src/transformers/tokenization_utils.py - Converts a string in a sequence of tokens, using the tokenizer. - - Args: - text (:obj:`str`): - The sequence to be encoded. - - Returns: - :obj:`List[str]`: The list of tokens. - """ - - def split_on_token(tok, text): - result = [] - split_text = text.split(tok) - for i, sub_text in enumerate(split_text): - # AddedToken can control whitespace stripping around them. - # We use them for GPT2 and Roberta to have different behavior depending on the special token - # Cf. https://github.com/huggingface/transformers/pull/2778 - # and https://github.com/huggingface/transformers/issues/3788 - # We strip left and right by default - if i < len(split_text) - 1: - sub_text = sub_text.rstrip() - if i > 0: - sub_text = sub_text.lstrip() - - if i == 0 and not sub_text: - result.append(tok) - elif i == len(split_text) - 1: - if sub_text: - result.append(sub_text) - else: - pass - else: - if sub_text: - result.append(sub_text) - result.append(tok) - return result - - def split_on_tokens(tok_list, text): - if not text.strip(): - return [] - - tokenized_text = [] - text_list = [text] - for tok in tok_list: - tokenized_text = [] - for sub_text in text_list: - if sub_text not in self.unique_no_split_tokens: - tokenized_text.extend(split_on_token(tok, sub_text)) - else: - tokenized_text.append(sub_text) - text_list = tokenized_text - - return list( - itertools.chain.from_iterable( - ( - self._tokenize(token) - if token not in self.unique_no_split_tokens - else [token] - for token in tokenized_text - ) - ) - ) - - no_split_token = self.unique_no_split_tokens - tokenized_text = split_on_tokens(no_split_token, text) - return tokenized_text - - def encode(self, text): - return [self.tok_to_idx[tok] for tok in self.tokenize(text)] - - -class BatchConverter(object): - """Callable to convert an unprocessed (labels + strings) batch to a - processed (labels + tensor) batch. - """ - - def __init__(self, alphabet): - self.alphabet = alphabet - - def __call__(self, raw_batch: Sequence[Tuple[str, str]]): - # RoBERTa uses an eos token, while ESM-1 does not. - batch_size = len(raw_batch) - batch_labels, seq_str_list = zip(*raw_batch) - seq_encoded_list = [self.alphabet.encode(seq_str) for seq_str in seq_str_list] - max_len = max(len(seq_encoded) for seq_encoded in seq_encoded_list) - tokens = torch.empty( - ( - batch_size, - max_len - + int(self.alphabet.prepend_bos) - + int(self.alphabet.append_eos), - ), - dtype=torch.int64, - ) - tokens.fill_(self.alphabet.padding_idx) - labels = [] - strs = [] - - for i, (label, seq_str, seq_encoded) in enumerate( - zip(batch_labels, seq_str_list, seq_encoded_list) - ): - labels.append(label) - strs.append(seq_str) - if self.alphabet.prepend_bos: - tokens[i, 0] = self.alphabet.cls_idx - seq = torch.tensor(seq_encoded, dtype=torch.int64) - tokens[ - i, - int(self.alphabet.prepend_bos) : len(seq_encoded) - + int(self.alphabet.prepend_bos), - ] = seq - if self.alphabet.append_eos: - tokens[ - i, len(seq_encoded) + int(self.alphabet.prepend_bos) - ] = self.alphabet.eos_idx - - return labels, strs, tokens - - -class MSABatchConverter(BatchConverter): - def __call__(self, inputs: Union[Sequence[RawMSA], RawMSA]): - if isinstance(inputs[0][0], str): - # Input is a single MSA - raw_batch: Sequence[RawMSA] = [inputs] # type: ignore - else: - raw_batch = inputs # type: ignore - - batch_size = len(raw_batch) - max_alignments = max(len(msa) for msa in raw_batch) - max_seqlen = max(len(msa[0][1]) for msa in raw_batch) - - tokens = torch.empty( - ( - batch_size, - max_alignments, - max_seqlen - + int(self.alphabet.prepend_bos) - + int(self.alphabet.append_eos), - ), - dtype=torch.int64, - ) - tokens.fill_(self.alphabet.padding_idx) - labels = [] - strs = [] - - for i, msa in enumerate(raw_batch): - msa_seqlens = set(len(seq) for _, seq in msa) - if not len(msa_seqlens) == 1: - raise RuntimeError( - "Received unaligned sequences for input to MSA, all sequence " - "lengths must be equal." - ) - msa_labels, msa_strs, msa_tokens = super().__call__(msa) - labels.append(msa_labels) - strs.append(msa_strs) - tokens[i, : msa_tokens.size(0), : msa_tokens.size(1)] = msa_tokens - - return labels, strs, tokens - - -def read_fasta( - path, - keep_gaps=True, - keep_insertions=True, - to_upper=False, -): - with open(path, "r") as f: - for result in read_alignment_lines( - f, keep_gaps=keep_gaps, keep_insertions=keep_insertions, to_upper=to_upper - ): - yield result - - -def read_alignment_lines( - lines, - keep_gaps=True, - keep_insertions=True, - to_upper=False, -): - seq = desc = None - - def parse(s): - if not keep_gaps: - s = re.sub("-", "", s) - if not keep_insertions: - s = re.sub("[a-z]", "", s) - return s.upper() if to_upper else s - - for line in lines: - # Line may be empty if seq % file_line_width == 0 - if len(line) > 0 and line[0] == ">": - if seq is not None: - yield desc, parse(seq) - desc = line.strip() - seq = "" - else: - assert isinstance(seq, str) - seq += line.strip() - assert isinstance(seq, str) and isinstance(desc, str) - yield desc, parse(seq) - - -class ESMStructuralSplitDataset(torch.utils.data.Dataset): - """ - Structural Split Dataset as described in section A.10 of the supplement of our paper. - https://doi.org/10.1101/622803 - - We use the full version of SCOPe 2.07, clustered at 90% sequence identity, - generated on January 23, 2020. - - For each SCOPe domain: - - We extract the sequence from the corresponding PDB file - - We extract the 3D coordinates of the Carbon beta atoms, aligning them - to the sequence. We put NaN where Cb atoms are missing. - - From the 3D coordinates, we calculate a pairwise distance map, based - on L2 distance - - We use DSSP to generate secondary structure labels for the corresponding - PDB file. This is also aligned to the sequence. We put - where SSP - labels are missing. - - For each SCOPe classification level of family/superfamily/fold (in order of difficulty), - we have split the data into 5 partitions for cross validation. These are provided - in a downloaded splits folder, in the format: - splits/{split_level}/{cv_partition}/{train|valid}.txt - where train is the partition and valid is the concatentation of the remaining 4. - - For each SCOPe domain, we provide a pkl dump that contains: - - seq : The domain sequence, stored as an L-length string - - ssp : The secondary structure labels, stored as an L-length string - - dist : The distance map, stored as an LxL numpy array - - coords : The 3D coordinates, stored as an Lx3 numpy array - - """ - - base_folder = "structural-data" - file_list = [ - # url tar filename filename MD5 Hash - ( - "https://dl.fbaipublicfiles.com/fair-esm/structural-data/splits.tar.gz", - "splits.tar.gz", - "splits", - "456fe1c7f22c9d3d8dfe9735da52411d", - ), - ( - "https://dl.fbaipublicfiles.com/fair-esm/structural-data/pkl.tar.gz", - "pkl.tar.gz", - "pkl", - "644ea91e56066c750cd50101d390f5db", - ), - ] - - def __init__( - self, - split_level, - cv_partition, - split, - root_path=os.path.expanduser("~/.cache/torch/data/esm"), - download=False, - ): - super().__init__() - assert split in [ - "train", - "valid", - ], "train_valid must be 'train' or 'valid'" - self.root_path = root_path - self.base_path = os.path.join(self.root_path, self.base_folder) - - # check if root path has what you need or else download it - if download: - self.download() - - self.split_file = os.path.join( - self.base_path, "splits", split_level, cv_partition, f"{split}.txt" - ) - self.pkl_dir = os.path.join(self.base_path, "pkl") - self.names = [] - with open(self.split_file) as f: - self.names = f.read().splitlines() - - def __len__(self): - return len(self.names) - - def _check_exists(self) -> bool: - for (_, _, filename, _) in self.file_list: - fpath = os.path.join(self.base_path, filename) - if not os.path.exists(fpath) or not os.path.isdir(fpath): - return False - return True - - def download(self): - - if self._check_exists(): - print("Files already downloaded and verified") - return - - from torchvision.datasets.utils import download_url - - for url, tar_filename, filename, md5_hash in self.file_list: - download_path = os.path.join(self.base_path, tar_filename) - download_url( - url=url, root=self.base_path, filename=tar_filename, md5=md5_hash - ) - shutil.unpack_archive(download_path, self.base_path) - - def __getitem__(self, idx): - """ - Returns a dict with the following entires - - seq : Str (domain sequence) - - ssp : Str (SSP labels) - - dist : np.array (distance map) - - coords : np.array (3D coordinates) - """ - name = self.names[idx] - pkl_fname = os.path.join(self.pkl_dir, name[1:3], f"{name}.pkl") - with open(pkl_fname, "rb") as f: - obj = pickle.load(f) - return obj diff --git a/esm/esm/model.py b/esm/esm/model.py deleted file mode 100644 index 308a004..0000000 --- a/esm/esm/model.py +++ /dev/null @@ -1,437 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import math - -import torch -import torch.nn as nn -import torch.nn.functional as F - -from .axial_attention import ColumnSelfAttention, RowSelfAttention -from .modules import (AxialTransformerLayer, ContactPredictionHead, - ESM1bLayerNorm, LearnedPositionalEmbedding, - RobertaLMHead, SinusoidalPositionalEmbedding, - TransformerLayer) - - -class ProteinBertModel(nn.Module): - @classmethod - def add_args(cls, parser): - parser.add_argument( - "--num_layers", default=36, type=int, metavar="N", help="number of layers" - ) - parser.add_argument( - "--embed_dim", - default=1280, - type=int, - metavar="N", - help="embedding dimension", - ) - parser.add_argument( - "--logit_bias", action="store_true", help="whether to apply bias to logits" - ) - parser.add_argument( - "--ffn_embed_dim", - default=5120, - type=int, - metavar="N", - help="embedding dimension for FFN", - ) - parser.add_argument( - "--attention_heads", - default=20, - type=int, - metavar="N", - help="number of attention heads", - ) - - def __init__(self, args, alphabet): - super().__init__() - self.args = args - self.alphabet_size = len(alphabet) - self.padding_idx = alphabet.padding_idx - self.mask_idx = alphabet.mask_idx - self.cls_idx = alphabet.cls_idx - self.eos_idx = alphabet.eos_idx - self.prepend_bos = alphabet.prepend_bos - self.append_eos = alphabet.append_eos - self.emb_layer_norm_before = getattr(self.args, "emb_layer_norm_before", False) - if self.args.arch == "roberta_large": - self.model_version = "ESM-1b" - self._init_submodules_esm1b() - else: - self.model_version = "ESM-1" - self._init_submodules_esm1() - - def _init_submodules_common(self): - self.embed_tokens = nn.Embedding( - self.alphabet_size, self.args.embed_dim, padding_idx=self.padding_idx - ) - self.layers = nn.ModuleList( - [ - TransformerLayer( - self.args.embed_dim, - self.args.ffn_embed_dim, - self.args.attention_heads, - add_bias_kv=(self.model_version != "ESM-1b"), - use_esm1b_layer_norm=(self.model_version == "ESM-1b"), - ) - for _ in range(self.args.layers) - ] - ) - - self.contact_head = ContactPredictionHead( - self.args.layers * self.args.attention_heads, - self.prepend_bos, - self.append_eos, - eos_idx=self.eos_idx, - ) - - def _init_submodules_esm1b(self): - self._init_submodules_common() - self.embed_scale = 1 - self.embed_positions = LearnedPositionalEmbedding( - self.args.max_positions, self.args.embed_dim, self.padding_idx - ) - self.emb_layer_norm_before = ( - ESM1bLayerNorm(self.args.embed_dim) if self.emb_layer_norm_before else None - ) - self.emb_layer_norm_after = ESM1bLayerNorm(self.args.embed_dim) - self.lm_head = RobertaLMHead( - embed_dim=self.args.embed_dim, - output_dim=self.alphabet_size, - weight=self.embed_tokens.weight, - ) - - def _init_submodules_esm1(self): - self._init_submodules_common() - self.embed_scale = math.sqrt(self.args.embed_dim) - self.embed_positions = SinusoidalPositionalEmbedding( - self.args.embed_dim, self.padding_idx - ) - self.embed_out = nn.Parameter( - torch.zeros((self.alphabet_size, self.args.embed_dim)) - ) - self.embed_out_bias = None - if self.args.final_bias: - self.embed_out_bias = nn.Parameter(torch.zeros(self.alphabet_size)) - - def forward( - self, tokens, repr_layers=[], need_head_weights=False, return_contacts=False - ): - if return_contacts: - need_head_weights = True - - assert tokens.ndim == 2 - padding_mask = tokens.eq(self.padding_idx) # B, T - - x = self.embed_scale * self.embed_tokens(tokens) - - if getattr(self.args, "token_dropout", False): - x.masked_fill_((tokens == self.mask_idx).unsqueeze(-1), 0.0) - # x: B x T x C - mask_ratio_train = 0.15 * 0.8 - src_lengths = (~padding_mask).sum(-1) - mask_ratio_observed = (tokens == self.mask_idx).sum( - -1 - ).float() / src_lengths - x = x * (1 - mask_ratio_train) / (1 - mask_ratio_observed)[:, None, None] - - x = x + self.embed_positions(tokens) - - if self.model_version == "ESM-1b": - if self.emb_layer_norm_before: - x = self.emb_layer_norm_before(x) - if padding_mask is not None: - x = x * (1 - padding_mask.unsqueeze(-1).type_as(x)) - - repr_layers = set(repr_layers) - hidden_representations = {} - if 0 in repr_layers: - hidden_representations[0] = x - - if need_head_weights: - attn_weights = [] - - # (B, T, E) => (T, B, E) - x = x.transpose(0, 1) - - if not padding_mask.any(): - padding_mask = None - - for layer_idx, layer in enumerate(self.layers): - x, attn = layer( - x, - self_attn_padding_mask=padding_mask, - need_head_weights=need_head_weights, - ) - if (layer_idx + 1) in repr_layers: - hidden_representations[layer_idx + 1] = x.transpose(0, 1) - if need_head_weights: - # (H, B, T, T) => (B, H, T, T) - attn_weights.append(attn.transpose(1, 0)) - - if self.model_version == "ESM-1b": - x = self.emb_layer_norm_after(x) - x = x.transpose(0, 1) # (T, B, E) => (B, T, E) - - # last hidden representation should have layer norm applied - if (layer_idx + 1) in repr_layers: - hidden_representations[layer_idx + 1] = x - x = self.lm_head(x) - else: - x = F.linear(x, self.embed_out, bias=self.embed_out_bias) - x = x.transpose(0, 1) # (T, B, E) => (B, T, E) - - result = {"logits": x, "representations": hidden_representations} - if need_head_weights: - # attentions: B x L x H x T x T - attentions = torch.stack(attn_weights, 1) - if self.model_version == "ESM-1": - # ESM-1 models have an additional null-token for attention, which we remove - attentions = attentions[..., :-1] - if padding_mask is not None: - attention_mask = 1 - padding_mask.type_as(attentions) - attention_mask = attention_mask.unsqueeze(1) * attention_mask.unsqueeze( - 2 - ) - attentions = attentions * attention_mask[:, None, None, :, :] - result["attentions"] = attentions - if return_contacts: - contacts = self.contact_head(tokens, attentions) - result["contacts"] = contacts - - return result - - def predict_contacts(self, tokens): - return self(tokens, return_contacts=True)["contacts"] - - @property - def num_layers(self): - return self.args.layers - - -class MSATransformer(nn.Module): - @classmethod - def add_args(cls, parser): - # fmt: off - parser.add_argument( - "--num_layers", - default=12, - type=int, - metavar="N", - help="number of layers" - ) - parser.add_argument( - "--embed_dim", - default=768, - type=int, - metavar="N", - help="embedding dimension" - ) - parser.add_argument( - "--logit_bias", - action="store_true", - help="whether to apply bias to logits" - ) - parser.add_argument( - "--ffn_embed_dim", - default=3072, - type=int, - metavar="N", - help="embedding dimension for FFN", - ) - parser.add_argument( - "--attention_heads", - default=12, - type=int, - metavar="N", - help="number of attention heads", - ) - parser.add_argument( - "--dropout", - default=0.1, - type=float, - help="Dropout to apply." - ) - parser.add_argument( - "--attention_dropout", - default=0.1, - type=float, - help="Dropout to apply." - ) - parser.add_argument( - "--activation_dropout", - default=0.1, - type=float, - help="Dropout to apply." - ) - parser.add_argument( - "--max_tokens_per_msa", - default=2 ** 14, - type=int, - help=( - "Used during inference to batch attention computations in a single " - "forward pass. This allows increased input sizes with less memory." - ), - ) - # fmt: on - - def __init__(self, args, alphabet): - super().__init__() - self.args = args - self.alphabet_size = len(alphabet) - self.padding_idx = alphabet.padding_idx - self.mask_idx = alphabet.mask_idx - self.cls_idx = alphabet.cls_idx - self.eos_idx = alphabet.eos_idx - self.prepend_bos = alphabet.prepend_bos - self.append_eos = alphabet.append_eos - - self.embed_tokens = nn.Embedding( - self.alphabet_size, self.args.embed_dim, padding_idx=self.padding_idx - ) - - if getattr(self.args, "embed_positions_msa", False): - emb_dim = getattr(self.args, "embed_positions_msa_dim", self.args.embed_dim) - self.msa_position_embedding = nn.Parameter( - 0.01 * torch.randn(1, 1024, 1, emb_dim), - requires_grad=True, - ) - else: - self.register_parameter("msa_position_embedding", None) - - self.dropout_module = nn.Dropout(self.args.dropout) - self.layers = nn.ModuleList( - [ - AxialTransformerLayer( - self.args.embed_dim, - self.args.ffn_embed_dim, - self.args.attention_heads, - self.args.dropout, - self.args.attention_dropout, - self.args.activation_dropout, - getattr(self.args, "max_tokens_per_msa", self.args.max_tokens), - ) - for _ in range(self.args.layers) - ] - ) - - self.contact_head = ContactPredictionHead( - self.args.layers * self.args.attention_heads, - self.prepend_bos, - self.append_eos, - eos_idx=self.eos_idx, - ) - self.embed_positions = LearnedPositionalEmbedding( - self.args.max_positions, - self.args.embed_dim, - self.padding_idx, - ) - self.emb_layer_norm_before = ESM1bLayerNorm(self.args.embed_dim) - self.emb_layer_norm_after = ESM1bLayerNorm(self.args.embed_dim) - self.lm_head = RobertaLMHead( - embed_dim=self.args.embed_dim, - output_dim=self.alphabet_size, - weight=self.embed_tokens.weight, - ) - - def forward( - self, tokens, repr_layers=[], need_head_weights=False, return_contacts=False - ): - if return_contacts: - need_head_weights = True - - assert tokens.ndim == 3 - batch_size, num_alignments, seqlen = tokens.size() - padding_mask = tokens.eq(self.padding_idx) # B, R, C - if not padding_mask.any(): - padding_mask = None - - x = self.embed_tokens(tokens) - x += self.embed_positions( - tokens.view(batch_size * num_alignments, seqlen) - ).view(x.size()) - if self.msa_position_embedding is not None: - if x.size(1) > 1024: - raise RuntimeError( - "Using model with MSA position embedding trained on maximum MSA " - f"depth of 1024, but received {x.size(1)} alignments." - ) - x += self.msa_position_embedding[:, :num_alignments] - - x = self.emb_layer_norm_before(x) - - x = self.dropout_module(x) - - if padding_mask is not None: - x = x * (1 - padding_mask.unsqueeze(-1).type_as(x)) - - repr_layers = set(repr_layers) - hidden_representations = {} - if 0 in repr_layers: - hidden_representations[0] = x - - if need_head_weights: - row_attn_weights = [] - col_attn_weights = [] - - # B x R x C x D -> R x C x B x D - x = x.permute(1, 2, 0, 3) - - for layer_idx, layer in enumerate(self.layers): - x = layer( - x, - self_attn_padding_mask=padding_mask, - need_head_weights=need_head_weights, - ) - if need_head_weights: - x, col_attn, row_attn = x - # H x C x B x R x R -> B x H x C x R x R - col_attn_weights.append(col_attn.permute(2, 0, 1, 3, 4)) - # H x B x C x C -> B x H x C x C - row_attn_weights.append(row_attn.permute(1, 0, 2, 3)) - if (layer_idx + 1) in repr_layers: - hidden_representations[layer_idx + 1] = x.permute(2, 0, 1, 3) - - x = self.emb_layer_norm_after(x) - x = x.permute(2, 0, 1, 3) # R x C x B x D -> B x R x C x D - - # last hidden representation should have layer norm applied - if (layer_idx + 1) in repr_layers: - hidden_representations[layer_idx + 1] = x - x = self.lm_head(x) - - result = {"logits": x, "representations": hidden_representations} - if need_head_weights: - # col_attentions: B x L x H x C x R x R - col_attentions = torch.stack(col_attn_weights, 1) - # row_attentions: B x L x H x C x C - row_attentions = torch.stack(row_attn_weights, 1) - result["col_attentions"] = col_attentions - result["row_attentions"] = row_attentions - if return_contacts: - contacts = self.contact_head(tokens, row_attentions) - result["contacts"] = contacts - - return result - - def predict_contacts(self, tokens): - return self(tokens, return_contacts=True)["contacts"] - - @property - def num_layers(self): - return self.args.layers - - def max_tokens_per_msa_(self, value: int) -> None: - """The MSA Transformer automatically batches attention computations when - gradients are disabled to allow you to pass in larger MSAs at test time than - you can fit in GPU memory. By default this occurs when more than 2^14 tokens - are passed in the input MSA. You can set this value to infinity to disable - this behavior. - """ - for module in self.modules(): - if isinstance(module, (RowSelfAttention, ColumnSelfAttention)): - module.max_tokens_per_msa = value diff --git a/esm/esm/modules.py b/esm/esm/modules.py deleted file mode 100644 index f099f09..0000000 --- a/esm/esm/modules.py +++ /dev/null @@ -1,436 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import math -from typing import Optional - -import torch -import torch.nn as nn -import torch.nn.functional as F - -from .axial_attention import ColumnSelfAttention, RowSelfAttention -from .multihead_attention import MultiheadAttention # noqa - - -def gelu(x): - """Implementation of the gelu activation function. - - For information: OpenAI GPT's gelu is slightly different - (and gives slightly different results): - 0.5 * x * (1 + torch.tanh(math.sqrt(2 / math.pi) * (x + 0.044715 * torch.pow(x, 3)))) - """ - return x * 0.5 * (1.0 + torch.erf(x / math.sqrt(2.0))) - - -def symmetrize(x): - "Make layer symmetric in final two dimensions, used for contact prediction." - return x + x.transpose(-1, -2) - - -def apc(x): - "Perform average product correct, used for contact prediction." - a1 = x.sum(-1, keepdims=True) - a2 = x.sum(-2, keepdims=True) - a12 = x.sum((-1, -2), keepdims=True) - - avg = a1 * a2 - avg.div_(a12) # in-place to reduce memory - normalized = x - avg - return normalized - - -class ESM1LayerNorm(nn.Module): - def __init__(self, hidden_size, eps=1e-12, affine=True): - """Construct a layernorm layer in the TF style (eps inside the sqrt).""" - super().__init__() - self.hidden_size = ( - (hidden_size,) if isinstance(hidden_size, int) else tuple(hidden_size) - ) - self.eps = eps - self.affine = bool(affine) - if self.affine: - self.weight = nn.Parameter(torch.ones(hidden_size)) - self.bias = nn.Parameter(torch.zeros(hidden_size)) - else: - self.weight, self.bias = None, None - - def forward(self, x): - dims = tuple(-(i + 1) for i in range(len(self.hidden_size))) - means = x.mean(dims, keepdim=True) - x_zeromean = x - means - variances = x_zeromean.pow(2).mean(dims, keepdim=True) - x = x_zeromean / torch.sqrt(variances + self.eps) - if self.affine: - x = (self.weight * x) + self.bias - return x - - -try: - from apex.normalization import FusedLayerNorm as _FusedLayerNorm - - class ESM1bLayerNorm(_FusedLayerNorm): - @torch.jit.unused - def forward(self, x): - if not x.is_cuda: - return super().forward(x) - else: - with torch.cuda.device(x.device): - return super().forward(x) - - -except ImportError: - from torch.nn import LayerNorm as ESM1bLayerNorm - - -class TransformerLayer(nn.Module): - """Transformer layer block.""" - - def __init__( - self, - embed_dim, - ffn_embed_dim, - attention_heads, - add_bias_kv=True, - use_esm1b_layer_norm=False, - ): - super().__init__() - self.embed_dim = embed_dim - self.ffn_embed_dim = ffn_embed_dim - self.attention_heads = attention_heads - self._init_submodules(add_bias_kv, use_esm1b_layer_norm) - - def _init_submodules(self, add_bias_kv, use_esm1b_layer_norm): - BertLayerNorm = ESM1bLayerNorm if use_esm1b_layer_norm else ESM1LayerNorm - - self.self_attn = MultiheadAttention( - self.embed_dim, - self.attention_heads, - add_bias_kv=add_bias_kv, - add_zero_attn=False, - ) - self.self_attn_layer_norm = BertLayerNorm(self.embed_dim) - - self.fc1 = nn.Linear(self.embed_dim, self.ffn_embed_dim) - self.fc2 = nn.Linear(self.ffn_embed_dim, self.embed_dim) - - self.final_layer_norm = BertLayerNorm(self.embed_dim) - - def forward( - self, - x, - self_attn_mask=None, - self_attn_padding_mask=None, - need_head_weights=False, - ): - residual = x - x = self.self_attn_layer_norm(x) - x, attn = self.self_attn( - query=x, - key=x, - value=x, - key_padding_mask=self_attn_padding_mask, - need_weights=True, - need_head_weights=need_head_weights, - attn_mask=self_attn_mask, - ) - x = residual + x - - residual = x - x = self.final_layer_norm(x) - x = gelu(self.fc1(x)) - x = self.fc2(x) - x = residual + x - - return x, attn - - -class AxialTransformerLayer(nn.Module): - """Implements an Axial MSA Transformer block.""" - - def __init__( - self, - embedding_dim: int = 768, - ffn_embedding_dim: int = 3072, - num_attention_heads: int = 8, - dropout: float = 0.1, - attention_dropout: float = 0.1, - activation_dropout: float = 0.1, - max_tokens_per_msa: int = 2 ** 14, - ) -> None: - super().__init__() - - # Initialize parameters - self.embedding_dim = embedding_dim - self.dropout_prob = dropout - - row_self_attention = RowSelfAttention( - embedding_dim, - num_attention_heads, - dropout=dropout, - max_tokens_per_msa=max_tokens_per_msa, - ) - - column_self_attention = ColumnSelfAttention( - embedding_dim, - num_attention_heads, - dropout=dropout, - max_tokens_per_msa=max_tokens_per_msa, - ) - - feed_forward_layer = FeedForwardNetwork( - embedding_dim, - ffn_embedding_dim, - activation_dropout=activation_dropout, - max_tokens_per_msa=max_tokens_per_msa, - ) - - self.row_self_attention = self.build_residual(row_self_attention) - self.column_self_attention = self.build_residual(column_self_attention) - self.feed_forward_layer = self.build_residual(feed_forward_layer) - - def build_residual(self, layer: nn.Module): - return NormalizedResidualBlock( - layer, - self.embedding_dim, - self.dropout_prob, - ) - - def forward( - self, - x: torch.Tensor, - self_attn_mask: Optional[torch.Tensor] = None, - self_attn_padding_mask: Optional[torch.Tensor] = None, - need_head_weights: bool = False, - ): - """ - LayerNorm is applied either before or after the self-attention/ffn - modules similar to the original Transformer implementation. - """ - x, row_attn = self.row_self_attention( - x, - self_attn_mask=self_attn_mask, - self_attn_padding_mask=self_attn_padding_mask, - ) - x, column_attn = self.column_self_attention( - x, - self_attn_mask=self_attn_mask, - self_attn_padding_mask=self_attn_padding_mask, - ) - x = self.feed_forward_layer(x) - if need_head_weights: - return x, column_attn, row_attn - else: - return x - - -class LearnedPositionalEmbedding(nn.Embedding): - """ - This module learns positional embeddings up to a fixed maximum size. - Padding ids are ignored by either offsetting based on padding_idx - or by setting padding_idx to None and ensuring that the appropriate - position ids are passed to the forward function. - """ - - def __init__(self, num_embeddings: int, embedding_dim: int, padding_idx: int): - if padding_idx is not None: - num_embeddings_ = num_embeddings + padding_idx + 1 - else: - num_embeddings_ = num_embeddings - super().__init__(num_embeddings_, embedding_dim, padding_idx) - self.max_positions = num_embeddings - - def forward(self, input: torch.Tensor): - """Input is expected to be of size [bsz x seqlen].""" - if input.size(1) > self.max_positions: - raise ValueError( - f"Sequence length {input.size(1)} above maximum " - f" sequence length of {self.max_positions}" - ) - mask = input.ne(self.padding_idx).int() - positions = ( - torch.cumsum(mask, dim=1).type_as(mask) * mask - ).long() + self.padding_idx - return F.embedding( - positions, - self.weight, - self.padding_idx, - self.max_norm, - self.norm_type, - self.scale_grad_by_freq, - self.sparse, - ) - - -class SinusoidalPositionalEmbedding(nn.Module): - def __init__(self, embed_dim, padding_idx, learned=False): - super().__init__() - self.embed_dim = embed_dim - self.padding_idx = padding_idx - self.register_buffer("_float_tensor", torch.FloatTensor(1)) - self.weights = None - - def forward(self, x): - bsz, seq_len = x.shape - max_pos = self.padding_idx + 1 + seq_len - if self.weights is None or max_pos > self.weights.size(0): - self.weights = self.get_embedding(max_pos) - self.weights = self.weights.type_as(self._float_tensor) - - positions = self.make_positions(x) - return ( - self.weights.index_select(0, positions.view(-1)) - .view(bsz, seq_len, -1) - .detach() - ) - - def make_positions(self, x): - mask = x.ne(self.padding_idx) - range_buf = ( - torch.arange(x.size(1), device=x.device).expand_as(x) + self.padding_idx + 1 - ) - positions = range_buf.expand_as(x) - return positions * mask.long() + self.padding_idx * (1 - mask.long()) - - def get_embedding(self, num_embeddings): - half_dim = self.embed_dim // 2 - emb = math.log(10000) / (half_dim - 1) - emb = torch.exp(torch.arange(half_dim, dtype=torch.float) * -emb) - emb = torch.arange(num_embeddings, dtype=torch.float).unsqueeze( - 1 - ) * emb.unsqueeze(0) - emb = torch.cat([torch.sin(emb), torch.cos(emb)], dim=1).view( - num_embeddings, -1 - ) - if self.embed_dim % 2 == 1: - # zero pad - emb = torch.cat([emb, torch.zeros(num_embeddings, 1)], dim=1) - if self.padding_idx is not None: - emb[self.padding_idx, :] = 0 - return emb - - -class RobertaLMHead(nn.Module): - """Head for masked language modeling.""" - - def __init__(self, embed_dim, output_dim, weight): - super().__init__() - self.dense = nn.Linear(embed_dim, embed_dim) - self.layer_norm = ESM1bLayerNorm(embed_dim) - self.weight = weight - self.bias = nn.Parameter(torch.zeros(output_dim)) - - def forward(self, features): - x = self.dense(features) - x = gelu(x) - x = self.layer_norm(x) - # project back to size of vocabulary with bias - x = F.linear(x, self.weight) + self.bias - return x - - -class ContactPredictionHead(nn.Module): - """Performs symmetrization, apc, and computes a logistic regression on the output features""" - - def __init__( - self, - in_features: int, - prepend_bos: bool, - append_eos: bool, - bias=True, - eos_idx: Optional[int] = None, - ): - super().__init__() - self.in_features = in_features - self.prepend_bos = prepend_bos - self.append_eos = append_eos - if append_eos and eos_idx is None: - raise ValueError( - "Using an alphabet with eos token, but no eos token was passed in." - ) - self.eos_idx = eos_idx - self.regression = nn.Linear(in_features, 1, bias) - self.activation = nn.Sigmoid() - - def forward(self, tokens, attentions): - # remove eos token attentions - if self.append_eos: - eos_mask = tokens.ne(self.eos_idx).to(attentions) - eos_mask = eos_mask.unsqueeze(1) * eos_mask.unsqueeze(2) - attentions = attentions * eos_mask[:, None, None, :, :] - attentions = attentions[..., :-1, :-1] - # remove cls token attentions - if self.prepend_bos: - attentions = attentions[..., 1:, 1:] - batch_size, layers, heads, seqlen, _ = attentions.size() - attentions = attentions.view(batch_size, layers * heads, seqlen, seqlen) - - # features: B x C x T x T - attentions = attentions.to( - next(self.parameters()) - ) # attentions always float32, may need to convert to float16 - attentions = apc(symmetrize(attentions)) - attentions = attentions.permute(0, 2, 3, 1) - return self.activation(self.regression(attentions).squeeze(3)) - - -class NormalizedResidualBlock(nn.Module): - def __init__( - self, - layer: nn.Module, - embedding_dim: int, - dropout: float = 0.1, - ): - super().__init__() - self.embedding_dim = embedding_dim - - self.layer = layer - self.dropout_module = nn.Dropout( - dropout, - ) - self.layer_norm = ESM1bLayerNorm(self.embedding_dim) - - def forward(self, x, *args, **kwargs): - residual = x - x = self.layer_norm(x) - outputs = self.layer(x, *args, **kwargs) - if isinstance(outputs, tuple): - x, *out = outputs - else: - x = outputs - out = None - - x = self.dropout_module(x) - x = residual + x - - if out is not None: - return (x,) + tuple(out) - else: - return x - - -class FeedForwardNetwork(nn.Module): - def __init__( - self, - embedding_dim: int, - ffn_embedding_dim: int, - activation_dropout: float = 0.1, - max_tokens_per_msa: int = 2 ** 14, - ): - super().__init__() - self.embedding_dim = embedding_dim - self.ffn_embedding_dim = ffn_embedding_dim - self.max_tokens_per_msa = max_tokens_per_msa - self.activation_fn = nn.GELU() - self.activation_dropout_module = nn.Dropout( - activation_dropout, - ) - self.fc1 = nn.Linear(embedding_dim, ffn_embedding_dim) - self.fc2 = nn.Linear(ffn_embedding_dim, embedding_dim) - - def forward(self, x): - x = self.activation_fn(self.fc1(x)) - x = self.activation_dropout_module(x) - x = self.fc2(x) - return x diff --git a/esm/esm/multihead_attention.py b/esm/esm/multihead_attention.py deleted file mode 100644 index cc55565..0000000 --- a/esm/esm/multihead_attention.py +++ /dev/null @@ -1,523 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import math -import uuid -from typing import Dict, Optional, Tuple - -import torch -import torch.nn.functional as F -from torch import Tensor, nn -from torch.nn import Parameter - - -def utils_softmax(x, dim: int, onnx_trace: bool = False): - if onnx_trace: - return F.softmax(x.float(), dim=dim) - else: - return F.softmax(x, dim=dim, dtype=torch.float32) - - -class FairseqIncrementalState(object): - def __init__(self, *args, **kwargs): - super().__init__(*args, **kwargs) - self.init_incremental_state() - - def init_incremental_state(self): - self._incremental_state_id = str(uuid.uuid4()) - - def _get_full_incremental_state_key(self, key: str) -> str: - return "{}.{}".format(self._incremental_state_id, key) - - def get_incremental_state( - self, - incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]], - key: str, - ) -> Optional[Dict[str, Optional[Tensor]]]: - """Helper for getting incremental state for an nn.Module.""" - full_key = self._get_full_incremental_state_key(key) - if incremental_state is None or full_key not in incremental_state: - return None - return incremental_state[full_key] - - def set_incremental_state( - self, - incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]], - key: str, - value: Dict[str, Optional[Tensor]], - ) -> Optional[Dict[str, Dict[str, Optional[Tensor]]]]: - """Helper for setting incremental state for an nn.Module.""" - if incremental_state is not None: - full_key = self._get_full_incremental_state_key(key) - incremental_state[full_key] = value - return incremental_state - - -def with_incremental_state(cls): - cls.__bases__ = (FairseqIncrementalState,) + tuple( - b for b in cls.__bases__ if b != FairseqIncrementalState - ) - return cls - - -@with_incremental_state -class MultiheadAttention(nn.Module): - """Multi-headed attention. - - See "Attention Is All You Need" for more details. - """ - - def __init__( - self, - embed_dim, - num_heads, - kdim=None, - vdim=None, - dropout=0.0, - bias=True, - add_bias_kv=False, - add_zero_attn=False, - self_attention=False, - encoder_decoder_attention=False, - ): - super().__init__() - self.embed_dim = embed_dim - self.kdim = kdim if kdim is not None else embed_dim - self.vdim = vdim if vdim is not None else embed_dim - self.qkv_same_dim = self.kdim == embed_dim and self.vdim == embed_dim - - self.num_heads = num_heads - self.dropout = dropout - self.head_dim = embed_dim // num_heads - assert ( - self.head_dim * num_heads == self.embed_dim - ), "embed_dim must be divisible by num_heads" - self.scaling = self.head_dim ** -0.5 - - self.self_attention = self_attention - self.encoder_decoder_attention = encoder_decoder_attention - - assert not self.self_attention or self.qkv_same_dim, ( - "Self-attention requires query, key and " "value to be of the same size" - ) - - self.k_proj = nn.Linear(self.kdim, embed_dim, bias=bias) - self.v_proj = nn.Linear(self.vdim, embed_dim, bias=bias) - self.q_proj = nn.Linear(embed_dim, embed_dim, bias=bias) - - self.out_proj = nn.Linear(embed_dim, embed_dim, bias=bias) - - if add_bias_kv: - self.bias_k = Parameter(torch.Tensor(1, 1, embed_dim)) - self.bias_v = Parameter(torch.Tensor(1, 1, embed_dim)) - else: - self.bias_k = self.bias_v = None - - self.add_zero_attn = add_zero_attn - - self.reset_parameters() - - self.onnx_trace = False - - self.enable_torch_version = False - if hasattr(F, "multi_head_attention_forward"): - self.enable_torch_version = True - else: - self.enable_torch_version = False - - def prepare_for_onnx_export_(self): - self.onnx_trace = True - - def reset_parameters(self): - if self.qkv_same_dim: - # Empirically observed the convergence to be much better with - # the scaled initialization - nn.init.xavier_uniform_(self.k_proj.weight, gain=1 / math.sqrt(2)) - nn.init.xavier_uniform_(self.v_proj.weight, gain=1 / math.sqrt(2)) - nn.init.xavier_uniform_(self.q_proj.weight, gain=1 / math.sqrt(2)) - else: - nn.init.xavier_uniform_(self.k_proj.weight) - nn.init.xavier_uniform_(self.v_proj.weight) - nn.init.xavier_uniform_(self.q_proj.weight) - - nn.init.xavier_uniform_(self.out_proj.weight) - if self.out_proj.bias is not None: - nn.init.constant_(self.out_proj.bias, 0.0) - if self.bias_k is not None: - nn.init.xavier_normal_(self.bias_k) - if self.bias_v is not None: - nn.init.xavier_normal_(self.bias_v) - - def forward( - self, - query, - key: Optional[Tensor], - value: Optional[Tensor], - key_padding_mask: Optional[Tensor] = None, - incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] = None, - need_weights: bool = True, - static_kv: bool = False, - attn_mask: Optional[Tensor] = None, - before_softmax: bool = False, - need_head_weights: bool = False, - ) -> Tuple[Tensor, Optional[Tensor]]: - """Input shape: Time x Batch x Channel - - Args: - key_padding_mask (ByteTensor, optional): mask to exclude - keys that are pads, of shape `(batch, src_len)`, where - padding elements are indicated by 1s. - need_weights (bool, optional): return the attention weights, - averaged over heads (default: False). - attn_mask (ByteTensor, optional): typically used to - implement causal attention, where the mask prevents the - attention from looking forward in time (default: None). - before_softmax (bool, optional): return the raw attention - weights and values before the attention softmax. - need_head_weights (bool, optional): return the attention - weights for each head. Implies *need_weights*. Default: - return the average attention weights over all heads. - """ - if need_head_weights: - need_weights = True - - tgt_len, bsz, embed_dim = query.size() - assert embed_dim == self.embed_dim - assert list(query.size()) == [tgt_len, bsz, embed_dim] - - if ( - self.enable_torch_version - and not self.onnx_trace - and incremental_state is None - and not static_kv - # A workaround for quantization to work. Otherwise JIT compilation - # treats bias in linear module as method. - and not torch.jit.is_scripting() - and not need_head_weights - ): - assert key is not None and value is not None - return F.multi_head_attention_forward( - query, - key, - value, - self.embed_dim, - self.num_heads, - torch.empty([0]), - torch.cat((self.q_proj.bias, self.k_proj.bias, self.v_proj.bias)), - self.bias_k, - self.bias_v, - self.add_zero_attn, - self.dropout, - self.out_proj.weight, - self.out_proj.bias, - self.training, - key_padding_mask, - need_weights, - attn_mask, - use_separate_proj_weight=True, - q_proj_weight=self.q_proj.weight, - k_proj_weight=self.k_proj.weight, - v_proj_weight=self.v_proj.weight, - ) - - if incremental_state is not None: - saved_state = self._get_input_buffer(incremental_state) - if saved_state is not None and "prev_key" in saved_state: - # previous time steps are cached - no need to recompute - # key and value if they are static - if static_kv: - assert self.encoder_decoder_attention and not self.self_attention - key = value = None - else: - saved_state = None - - if self.self_attention: - q = self.q_proj(query) - k = self.k_proj(query) - v = self.v_proj(query) - elif self.encoder_decoder_attention: - # encoder-decoder attention - q = self.q_proj(query) - if key is None: - assert value is None - k = v = None - else: - k = self.k_proj(key) - v = self.v_proj(key) - - else: - assert key is not None and value is not None - q = self.q_proj(query) - k = self.k_proj(key) - v = self.v_proj(value) - q *= self.scaling - - if self.bias_k is not None: - assert self.bias_v is not None - k = torch.cat([k, self.bias_k.repeat(1, bsz, 1)]) - v = torch.cat([v, self.bias_v.repeat(1, bsz, 1)]) - if attn_mask is not None: - attn_mask = torch.cat( - [attn_mask, attn_mask.new_zeros(attn_mask.size(0), 1)], dim=1 - ) - if key_padding_mask is not None: - key_padding_mask = torch.cat( - [ - key_padding_mask, - key_padding_mask.new_zeros(key_padding_mask.size(0), 1), - ], - dim=1, - ) - - q = ( - q.contiguous() - .view(tgt_len, bsz * self.num_heads, self.head_dim) - .transpose(0, 1) - ) - if k is not None: - k = ( - k.contiguous() - .view(-1, bsz * self.num_heads, self.head_dim) - .transpose(0, 1) - ) - if v is not None: - v = ( - v.contiguous() - .view(-1, bsz * self.num_heads, self.head_dim) - .transpose(0, 1) - ) - - if saved_state is not None: - # saved states are stored with shape (bsz, num_heads, seq_len, head_dim) - if "prev_key" in saved_state: - _prev_key = saved_state["prev_key"] - assert _prev_key is not None - prev_key = _prev_key.view(bsz * self.num_heads, -1, self.head_dim) - if static_kv: - k = prev_key - else: - assert k is not None - k = torch.cat([prev_key, k], dim=1) - if "prev_value" in saved_state: - _prev_value = saved_state["prev_value"] - assert _prev_value is not None - prev_value = _prev_value.view(bsz * self.num_heads, -1, self.head_dim) - if static_kv: - v = prev_value - else: - assert v is not None - v = torch.cat([prev_value, v], dim=1) - prev_key_padding_mask: Optional[Tensor] = None - if "prev_key_padding_mask" in saved_state: - prev_key_padding_mask = saved_state["prev_key_padding_mask"] - assert k is not None and v is not None - key_padding_mask = MultiheadAttention._append_prev_key_padding_mask( - key_padding_mask=key_padding_mask, - prev_key_padding_mask=prev_key_padding_mask, - batch_size=bsz, - src_len=k.size(1), - static_kv=static_kv, - ) - - saved_state["prev_key"] = k.view(bsz, self.num_heads, -1, self.head_dim) - saved_state["prev_value"] = v.view(bsz, self.num_heads, -1, self.head_dim) - saved_state["prev_key_padding_mask"] = key_padding_mask - # In this branch incremental_state is never None - assert incremental_state is not None - incremental_state = self._set_input_buffer(incremental_state, saved_state) - assert k is not None - src_len = k.size(1) - - # This is part of a workaround to get around fork/join parallelism - # not supporting Optional types. - if key_padding_mask is not None and key_padding_mask.dim() == 0: - key_padding_mask = None - - if key_padding_mask is not None: - assert key_padding_mask.size(0) == bsz - assert key_padding_mask.size(1) == src_len - - if self.add_zero_attn: - assert v is not None - src_len += 1 - k = torch.cat([k, k.new_zeros((k.size(0), 1) + k.size()[2:])], dim=1) - v = torch.cat([v, v.new_zeros((v.size(0), 1) + v.size()[2:])], dim=1) - if attn_mask is not None: - attn_mask = torch.cat( - [attn_mask, attn_mask.new_zeros(attn_mask.size(0), 1)], dim=1 - ) - if key_padding_mask is not None: - key_padding_mask = torch.cat( - [ - key_padding_mask, - torch.zeros(key_padding_mask.size(0), 1).type_as( - key_padding_mask - ), - ], - dim=1, - ) - - attn_weights = torch.bmm(q, k.transpose(1, 2)) - attn_weights = MultiheadAttention.apply_sparse_mask( - attn_weights, tgt_len, src_len, bsz - ) - - assert list(attn_weights.size()) == [bsz * self.num_heads, tgt_len, src_len] - - if attn_mask is not None: - attn_mask = attn_mask.unsqueeze(0) - if self.onnx_trace: - attn_mask = attn_mask.repeat(attn_weights.size(0), 1, 1) - attn_weights += attn_mask - - if key_padding_mask is not None: - # don't attend to padding symbols - attn_weights = attn_weights.view(bsz, self.num_heads, tgt_len, src_len) - attn_weights = attn_weights.masked_fill( - key_padding_mask.unsqueeze(1).unsqueeze(2).to(torch.bool), float("-inf") - ) - attn_weights = attn_weights.view(bsz * self.num_heads, tgt_len, src_len) - - if before_softmax: - return attn_weights, v - - attn_weights_float = utils_softmax( - attn_weights, dim=-1, onnx_trace=self.onnx_trace - ) - attn_weights = attn_weights_float.type_as(attn_weights) - attn_probs = F.dropout( - attn_weights_float.type_as(attn_weights), - p=self.dropout, - training=self.training, - ) - assert v is not None - attn = torch.bmm(attn_probs, v) - assert list(attn.size()) == [bsz * self.num_heads, tgt_len, self.head_dim] - if self.onnx_trace and attn.size(1) == 1: - # when ONNX tracing a single decoder step (sequence length == 1) - # the transpose is a no-op copy before view, thus unnecessary - attn = attn.contiguous().view(tgt_len, bsz, embed_dim) - else: - attn = attn.transpose(0, 1).contiguous().view(tgt_len, bsz, embed_dim) - attn = self.out_proj(attn) - attn_weights: Optional[Tensor] = None - if need_weights: - attn_weights = attn_weights_float.view( - bsz, self.num_heads, tgt_len, src_len - ).transpose(1, 0) - if not need_head_weights: - # average attention weights over heads - attn_weights = attn_weights.mean(dim=0) - - return attn, attn_weights - - @staticmethod - def _append_prev_key_padding_mask( - key_padding_mask: Optional[Tensor], - prev_key_padding_mask: Optional[Tensor], - batch_size: int, - src_len: int, - static_kv: bool, - ) -> Optional[Tensor]: - # saved key padding masks have shape (bsz, seq_len) - if prev_key_padding_mask is not None and static_kv: - new_key_padding_mask = prev_key_padding_mask - elif prev_key_padding_mask is not None and key_padding_mask is not None: - new_key_padding_mask = torch.cat( - [prev_key_padding_mask.float(), key_padding_mask.float()], dim=1 - ) - # During incremental decoding, as the padding token enters and - # leaves the frame, there will be a time when prev or current - # is None - elif prev_key_padding_mask is not None: - filler = torch.zeros( - (batch_size, src_len - prev_key_padding_mask.size(1)), - device=prev_key_padding_mask.device, - ) - new_key_padding_mask = torch.cat( - [prev_key_padding_mask.float(), filler.float()], dim=1 - ) - elif key_padding_mask is not None: - filler = torch.zeros( - (batch_size, src_len - key_padding_mask.size(1)), - device=key_padding_mask.device, - ) - new_key_padding_mask = torch.cat( - [filler.float(), key_padding_mask.float()], dim=1 - ) - else: - new_key_padding_mask = prev_key_padding_mask - return new_key_padding_mask - - @torch.jit.export - def reorder_incremental_state( - self, - incremental_state: Dict[str, Dict[str, Optional[Tensor]]], - new_order: Tensor, - ): - """Reorder buffered internal state (for incremental generation).""" - input_buffer = self._get_input_buffer(incremental_state) - if input_buffer is not None: - for k in input_buffer.keys(): - input_buffer_k = input_buffer[k] - if input_buffer_k is not None: - if self.encoder_decoder_attention and input_buffer_k.size( - 0 - ) == new_order.size(0): - break - input_buffer[k] = input_buffer_k.index_select(0, new_order) - incremental_state = self._set_input_buffer(incremental_state, input_buffer) - return incremental_state - - def _get_input_buffer( - self, incremental_state: Optional[Dict[str, Dict[str, Optional[Tensor]]]] - ) -> Dict[str, Optional[Tensor]]: - result = self.get_incremental_state(incremental_state, "attn_state") - if result is not None: - return result - else: - empty_result: Dict[str, Optional[Tensor]] = {} - return empty_result - - def _set_input_buffer( - self, - incremental_state: Dict[str, Dict[str, Optional[Tensor]]], - buffer: Dict[str, Optional[Tensor]], - ): - return self.set_incremental_state(incremental_state, "attn_state", buffer) - - def apply_sparse_mask(attn_weights, tgt_len: int, src_len: int, bsz: int): - return attn_weights - - def upgrade_state_dict_named(self, state_dict, name): - prefix = name + "." if name != "" else "" - items_to_add = {} - keys_to_remove = [] - for k in state_dict.keys(): - if k.endswith(prefix + "in_proj_weight"): - # in_proj_weight used to be q + k + v with same dimensions - dim = int(state_dict[k].shape[0] / 3) - items_to_add[prefix + "q_proj.weight"] = state_dict[k][:dim] - items_to_add[prefix + "k_proj.weight"] = state_dict[k][dim : 2 * dim] - items_to_add[prefix + "v_proj.weight"] = state_dict[k][2 * dim :] - - keys_to_remove.append(k) - - k_bias = prefix + "in_proj_bias" - if k_bias in state_dict.keys(): - dim = int(state_dict[k].shape[0] / 3) - items_to_add[prefix + "q_proj.bias"] = state_dict[k_bias][:dim] - items_to_add[prefix + "k_proj.bias"] = state_dict[k_bias][ - dim : 2 * dim - ] - items_to_add[prefix + "v_proj.bias"] = state_dict[k_bias][2 * dim :] - - keys_to_remove.append(prefix + "in_proj_bias") - - for k in keys_to_remove: - del state_dict[k] - - for key, value in items_to_add.items(): - state_dict[key] = value diff --git a/esm/esm/pretrained.py b/esm/esm/pretrained.py deleted file mode 100644 index 3e5111c..0000000 --- a/esm/esm/pretrained.py +++ /dev/null @@ -1,292 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import urllib -import warnings -from argparse import Namespace -from pathlib import Path - -import torch - -import esm - - -def _has_regression_weights(model_name): - """Return whether we expect / require regression weights; - Right now that is all models except ESM-1v""" - return not ("esm1v" in model_name) - - -def load_model_and_alphabet(model_name): - if model_name.endswith(".pt"): # treat as filepath - return load_model_and_alphabet_local(model_name) - else: - return load_model_and_alphabet_hub(model_name) - - -def load_hub_workaround(url): - try: - data = torch.hub.load_state_dict_from_url( - url, progress=False, map_location="cpu" - ) - except RuntimeError: - # Pytorch version issue - see https://github.com/pytorch/pytorch/issues/43106 - fn = Path(url).name - data = torch.load( - f"{torch.hub.get_dir()}/checkpoints/{fn}", - map_location="cpu", - ) - except urllib.error.HTTPError as e: - raise Exception( - f"Could not load {url}, check if you specified a correct model name?" - ) - return data - - -def load_regression_hub(model_name): - url = f"https://dl.fbaipublicfiles.com/fair-esm/regression/{model_name}-contact-regression.pt" - regression_data = load_hub_workaround(url) - return regression_data - - -def load_model_and_alphabet_hub(model_name): - url = f"https://dl.fbaipublicfiles.com/fair-esm/models/{model_name}.pt" - model_data = load_hub_workaround(url) - if _has_regression_weights(model_name): - regression_data = load_regression_hub(model_name) - else: - regression_data = None - return load_model_and_alphabet_core(model_data, regression_data) - - -def load_model_and_alphabet_local(model_location): - """Load from local path. The regression weights need to be co-located""" - model_location = Path(model_location) - model_data = torch.load(str(model_location), map_location="cpu") - model_name = model_location.stem - if _has_regression_weights(model_name): - regression_location = ( - str(model_location.with_suffix("")) + "-contact-regression.pt" - ) - regression_data = torch.load(regression_location, map_location="cpu") - else: - regression_data = None - return load_model_and_alphabet_core(model_data, regression_data) - - -def has_emb_layer_norm_before(model_state): - """Determine whether layer norm needs to be applied before the encoder""" - return any( - k.startswith("emb_layer_norm_before") for k, param in model_state.items() - ) - - -def load_model_and_alphabet_core(model_data, regression_data=None): - if regression_data is not None: - model_data["model"].update(regression_data["model"]) - - alphabet = esm.Alphabet.from_architecture(model_data["args"].arch) - - if model_data["args"].arch == "roberta_large": - # upgrade state dict - pra = lambda s: "".join(s.split("encoder_")[1:] if "encoder" in s else s) - prs1 = lambda s: "".join(s.split("encoder.")[1:] if "encoder" in s else s) - prs2 = lambda s: "".join( - s.split("sentence_encoder.")[1:] if "sentence_encoder" in s else s - ) - model_args = {pra(arg[0]): arg[1] for arg in vars(model_data["args"]).items()} - model_state = { - prs1(prs2(arg[0])): arg[1] for arg in model_data["model"].items() - } - model_state["embed_tokens.weight"][alphabet.mask_idx].zero_() # For token drop - model_args["emb_layer_norm_before"] = has_emb_layer_norm_before(model_state) - model_type = esm.ProteinBertModel - - elif model_data["args"].arch == "protein_bert_base": - - # upgrade state dict - pra = lambda s: "".join(s.split("decoder_")[1:] if "decoder" in s else s) - prs = lambda s: "".join(s.split("decoder.")[1:] if "decoder" in s else s) - model_args = {pra(arg[0]): arg[1] for arg in vars(model_data["args"]).items()} - model_state = {prs(arg[0]): arg[1] for arg in model_data["model"].items()} - model_type = esm.ProteinBertModel - elif model_data["args"].arch == "msa_transformer": - - # upgrade state dict - pra = lambda s: "".join(s.split("encoder_")[1:] if "encoder" in s else s) - prs1 = lambda s: "".join(s.split("encoder.")[1:] if "encoder" in s else s) - prs2 = lambda s: "".join( - s.split("sentence_encoder.")[1:] if "sentence_encoder" in s else s - ) - prs3 = ( - lambda s: s.replace("row", "column") - if "row" in s - else s.replace("column", "row") - ) - model_args = {pra(arg[0]): arg[1] for arg in vars(model_data["args"]).items()} - model_state = { - prs1(prs2(prs3(arg[0]))): arg[1] for arg in model_data["model"].items() - } - if model_args.get("embed_positions_msa", False): - emb_dim = model_state["msa_position_embedding"].size(-1) - model_args[ - "embed_positions_msa_dim" - ] = emb_dim # initial release, bug: emb_dim==1 - - model_type = esm.MSATransformer - - else: - raise ValueError("Unknown architecture selected") - - model = model_type( - Namespace(**model_args), - alphabet, - ) - - expected_keys = set(model.state_dict().keys()) - found_keys = set(model_state.keys()) - - if regression_data is None: - expected_missing = { - "contact_head.regression.weight", - "contact_head.regression.bias", - } - error_msgs = [] - missing = (expected_keys - found_keys) - expected_missing - if missing: - error_msgs.append(f"Missing key(s) in state_dict: {missing}.") - unexpected = found_keys - expected_keys - if unexpected: - error_msgs.append(f"Unexpected key(s) in state_dict: {unexpected}.") - - if error_msgs: - raise RuntimeError( - "Error(s) in loading state_dict for {}:\n\t{}".format( - model.__class__.__name__, "\n\t".join(error_msgs) - ) - ) - if expected_missing - found_keys: - warnings.warn( - "Regression weights not found, predicting contacts will not produce correct results." - ) - - model.load_state_dict(model_state, strict=regression_data is not None) - - return model, alphabet - - -def esm1_t34_670M_UR50S(): - """34 layer transformer model with 670M params, trained on Uniref50 Sparse. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1_t34_670M_UR50S") - - -def esm1_t34_670M_UR50D(): - """34 layer transformer model with 670M params, trained on Uniref50 Dense. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1_t34_670M_UR50D") - - -def esm1_t34_670M_UR100(): - """34 layer transformer model with 670M params, trained on Uniref100. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1_t34_670M_UR100") - - -def esm1_t12_85M_UR50S(): - """12 layer transformer model with 85M params, trained on Uniref50 Sparse. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1_t12_85M_UR50S") - - -def esm1_t6_43M_UR50S(): - """6 layer transformer model with 43M params, trained on Uniref50 Sparse. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1_t6_43M_UR50S") - - -def esm1b_t33_650M_UR50S(): - """33 layer transformer model with 650M params, trained on Uniref50 Sparse. - This is our best performing model, which will be described in a future publication. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1b_t33_650M_UR50S") - - -def esm_msa1_t12_100M_UR50S(): - warnings.warn( - "This model had a minor bug in the positional embeddings, " - "please use ESM-MSA-1b: esm.pretrained.esm_msa1b_t12_100M_UR50S()", - ) - return load_model_and_alphabet_hub("esm_msa1_t12_100M_UR50S") - - -def esm_msa1b_t12_100M_UR50S(): - return load_model_and_alphabet_hub("esm_msa1b_t12_100M_UR50S") - - -def esm1v_t33_650M_UR90S(): - """33 layer transformer model with 650M params, trained on Uniref90. - This is model 1 of a 5 model ensemble. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_1") - - -def esm1v_t33_650M_UR90S_1(): - """33 layer transformer model with 650M params, trained on Uniref90. - This is model 1 of a 5 model ensemble. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_1") - - -def esm1v_t33_650M_UR90S_2(): - """33 layer transformer model with 650M params, trained on Uniref90. - This is model 2 of a 5 model ensemble. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_2") - - -def esm1v_t33_650M_UR90S_3(): - """33 layer transformer model with 650M params, trained on Uniref90. - This is model 3 of a 5 model ensemble. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_3") - - -def esm1v_t33_650M_UR90S_4(): - """33 layer transformer model with 650M params, trained on Uniref90. - This is model 4 of a 5 model ensemble. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_4") - - -def esm1v_t33_650M_UR90S_5(): - """33 layer transformer model with 650M params, trained on Uniref90. - This is model 5 of a 5 model ensemble. - - Returns a tuple of (Model, Alphabet). - """ - return load_model_and_alphabet_hub("esm1v_t33_650M_UR90S_5") diff --git a/esm/esm/version.py b/esm/esm/version.py deleted file mode 100644 index ab4242d..0000000 --- a/esm/esm/version.py +++ /dev/null @@ -1,6 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -version = "0.4.0" diff --git a/esm/examples/1a3a_1_A.a3m b/esm/examples/1a3a_1_A.a3m deleted file mode 100644 index 96e7ec7..0000000 --- a/esm/examples/1a3a_1_A.a3m +++ /dev/null @@ -1,2048 +0,0 @@ -> -LFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLAGRK -> --MKLKTELIKLNANPTDKTEAIKVIAQLFVDADCTTAEYLSGMLAREEQENTYLGKGVAIPHGTPEVRDQIKETSIAVMQIPQGLEWGEDE--PVHLAIGIAANSDEHLQILGKLVRILNNQEQLDTLINTDDASVIQAALSD-- -> ---MLQKENIFFNLCSDSKETILKDLGNGLLATGYVTNDYVKSIIKREQEMSTYLSNGVAVPHGLTSSAEGILKNGVAIATIPDGIDWGNGQ--IVRVIIMIAAERRAHMNVLAKAAKLCSDESKVKAILTMTVD-EIYDKCRF-- -> -VLDINKRDISFAQTAKNKTDALTMIVHDLISKGCVDSGYLKGVFQREAQSSTYLGHGIAIPHGTVETRSKVNKTGLSIFHFADGIDWDNGQ--TVHLVIGIAAKSDEHLDILKRLTHLLSDKDIDNNIANLENIEQIVELLSPT- -> -MLQLDTNTITLNQSSDNKLNAIKAIAADLTSKGLVQDGYVDGMLNREGQNSTFLGNGIAIPHGTTDTRDLVKQTGVAVHHFPNGVDWGDGN--VAYVAIGIAAKSDEHLGILKQLTKILSADGVEQKLKQAKSEKDIIALLNGDV -> -MLTLRQDDVLLGCRAEHWRDALDQAAESLHAAGLVAPEYRDGLHAREAQSSTFLGNAIAIPHGTPESREHVRATGVRVLQFPEGIEWHDGQ--RVHVLVTIAAQSDEHLDILRQLTHVLDQDGIAERLAGAERAAEIAELLSKA- -> -SEILSIRSVQLAAAFDHKNDVIRAAGELLVQVGAVDKSYLASMLQREAITNTWLGNGIAIPHGMVENHNLIIRDAVAVIQIPAGVEWRDGK--KARLVIAIAAYPDRYREICRQLAPLLYDKERLEALSTTTDKQQIVTTLFGQ- -> -TLMVSPEQIVLNANVTTKDDVLELISQNLSSLGLVRGNYLDALRGREDKVSTYLINGVAIPHGVNEAKEQVIKSGVFIVQAPTGVTWNDKG-DVARLIVGISAKGKDHLSLLQRLTEVVMDEALAEQLATTTDKADILNALNGA- -> --MSTIPVEVRLGAAPHNREDAVRAAGALLAQAGHIQHAYIDSLLQREKVANTFLGEGLAIPHGMVEDKHLVQRTGLAVLQVPAGVRWGDDA-KQAHLVVAIAAATDDHIQVLRRLTRLMRDSALMRRLATTTDAGEIVRALTAD- -> -PTSGVEELVRIDARVVNKVDAIRQVGQLLAAAGCVSPDYEDSMVAREEIANTFLGAGVAIPHGLGEDKGKVRRDGIAILQLRDGVEWNPGQ--RAHIVVGIAANSDNHIAILRRLTRLIQDEARLEDLRTTGNPDDFRRALWAD- -> -TDILSLKSIQLSAVFSHKNDAIYAAVKLLMGSDVIKQHHLGGIIGSKLIASIWFRSGVAVIYGITESYQLVMRDAVSVVQIPAGVEWQDER--RVYLVIAVITCADLHIKILKKIAPILFDEQKLKELSVIEDKQKIITALLGR- -> -RCALTSKNIQLGTKIASKQAAIEEAGRVLASLGCIESGYIRSMFEREKMETTYLGKGIAIPHGLPKDRALVHQTGISVVQIPAGVCWGPGQ--IAYLIVGIAAKSDEHVSILAAVAEICNDSGAISRLARTDDVEEIIYALTTQ- -> -MTILSKDRISLQTSASDKADAIRKAGQLLVATGCVLPEYVDGMLAREQSMSTSLGNGVAIPHGVYENRGHILKTGISVLQLPAGVDWDEGE--MIYLVIGIAAQGDEHVGVLANLAEVIDDENNLAELFQTTDPEVIVKYLGA-- -> -MSQLLKSHIFLQQFAPSKYQALKLACLKLVEAGMVCPGYFHGMCRRELLSSTYLDNGIAVPHSVPDTRSEINYSGMIIIQFPRGVNWGNND--RTFLLCALAARGKEHLQMLSHLACSLDDTDLCRKLAVTEEVEHIYQSVTR-- -> -QDVLTRDLVVAPGTARTKEEAIREAGALLVGCGSVTPAYVDAMAAREQLVSTYMGSWLAIPHGTDESKGDIVASALCLIRYDEPIEWGAGQ--PVRVVVGIAGVGEEHLSILSKIALIFSDPTEVEKVLAAAGPDELYALIQQ-- -> --MRFERNLIFIKTDFRDKTAVVEFLGGQLVQAGAVQPAYVQAMHQREQDVGTYITEGVAIPHGTEGSRSLVNRAAIVALKIPRGIEWSDGK--PVFLAFGIAGNEEDHVSLLSELAIMLMDADQKAKLLAAENEDDLFACLNQ-- -> -MLKLSEDSLHLQCRAANKNEAIKIAANALEKAGYVKPGFMEGMLAREKSVSTYIGAGVAFPHCAKENLDLVLKTGFQVFQFPQGVSWGAGK--VVFVVVAVAATGNQHIQVLADIASLLGDEVKTTLLASAKTKQEFISQFEK-- -> -MLKLNENDLFLHCQAANKNEAMQLAAAALEQGGYVKTGFFHAMQAREESVSTYIGAGIAFPHCAKADTHLVINTGFQVFQFPQGVSWGAGK--VVFIVVAVAAQQDEHIQVLAAIADLLGDEVKTTLLANANTKAGFIEQFEK-- -> ---MYDEKNIFMNCKFADKETALNQVLEVMLAGGC-DQEYVDSILERQKIASFNLGNLVAAPHGTYEISKKVKKPKIFIWHLKEELLWDGE---PIRLILGLYLQPNNQLEALQTVAINTIDEILFNNLLAKPTLNKLIKFTSE-- -> -GAILAREGIKLGLPTVSMEEAIVAAGELLRDLGYVDDDYIPAMIRRNEEASVYMGLGLAIPHGTEDAKRNVKKSGIIVMQYPDGVEFNGG---TAQLVIGIAGVGDEHLEILGQITEAVTEEEILEELKKTTDVDYILKTFANM- -> -GEIIKESMIVVDAKVRDKFEAIKMAGEILVKEGYVEPEYIDAMFERERMLSTYIGNFIAIPHGVGESKKYIKKTGLSVIHVSDGVDFGDNN--IVYLVIGIAALGDEHLNILANIATLFENEEKVKKLIQNPSRKEIFDFLNGR- -> -LSNEFQKHICLDYECTTIEEAIHKAGNLLVQTGCVKPPYINGMLRREQETSTDIGFGVMIPHGTEDTLDFVLKPGISIVQIPHGISYHGNP--I-HLVIGISSREEDPLQELMQITDILLKPEKCHQFLNASSKQEFIDMINQN- -> -PQILKVENIRINQQAASSDEAIVRVGNALKDAGYIEEGYIQGMLNRDHNLTTYIGNDIAIPHGEYEVKDCVKQTGLAVDIYPDGIAWGGG---IVRIVIGIAATTDEHITILQNIAEQLGDMDVVEQVVKGSPE-FIHSVLTGG- -> -LNDEFQKHICLDFECTTIEEAIRKAGDLLVQCGCIKPPYIDGMIRREQEHSTHIGFGVMIPHGTEDTLDCVISPGISILKISNGVPYHGTM--I-TMVIGIASREEDPLQELMQITDILLTPEKCDQFLNASSKQEFIDMINQH- -> -NDILNPANIRLNQKASCSDDAIVSVGKQLMNAGYIEEPYIQGMLNRDHDLTTYIGNDIAIPHGEYEVKDYVKKTGLAVDIYPDGIEWAGN---KVRIVIGIAATTDEHVRILQNIAEKLCDMEMVEKVVSGNQD-TIHQILAIT- -> -MEALDKKMIALNQQVATQEEGIRLAGQLLVDGGCVEPEYIDAMQARNQDVSVYMGNFIAIPHGTEDGMKYIKKTGISVVQVPMGVSWGNPDN-DVTVIFGIAGLNGEHLNLLSQIAIYCSDVANVAKLADAQSEDEIINLLKEV- -> -ERLLSEKTVLLGASFPDKVAAIRACGELLVAAGYAERPYIDAMVARDEMSTIYIGNGVALPHGTEASRRYVKRTGLAIVQVPGGVDFGKGN--VARLLVAVAALGEEHIDLLTEIAQICVDDEMLDRLINAATASELLSVIAPE- -> -LPILMKENIIIEKQTMSVKEAIDKVGAMMIKSGYVKKGYIDGMHRRDEDLSVFLGNLLAIPHGVHDVKDEIIASGMVVLIVPDGIDWHGN---VAKVIIGLAGKDGEHMSILANLATIFEELETAQKLVDSRDIDFIYQTMTQ-- -> -KPVLIKENIVLDCKAVTPEEAIIHAGELLLRSGYIKSGYISGMLSRDENFSVYLGNMLAIAHGEKGVRDQILGTGMSVLICPDGIDWHGN---LVKIVMGLAAIGDEHMELLMHCANIFSDRERVERLVRCRDRERVYRMFGGI- -> -MIEISNESIWLNQSFDSWEQALNKIGEILREAGYITKEYIASMIDRQKLASVYIGNFVALPHALA-KDEHIIKENIFLFQVPDGVDFGAEE--EATILFVVVLKEKHQLENLQELAFLCSDVDQVMALSDAQTVDEIQIILKKA- -> -MKLLEEKNISLNQTFKTPQEAIIYAGEKMKSLGLIKEEYIESMLVRQDKLSVYIGNFVALPHGEV-QDEFILEEGIFVTQVPDGIDFSNTE--QATIIISVALRKESQLRILQELAFFCSDIENVRKLSDEVDEKQFVTFFNES- -> -QTILTADKIKLDAKPATKKEAITMAGQLLVQAGCVSEDYIQSMMEREELQTTYMGFGVAIPHGTKEAKTFIRSTGISVVQVREGVDFGNGN--VAKILIGIAAVGDEHLDIIQNLALLISEEENVDKLVHADTAKAVIDMIEQG- -> -KISVEKENIFLNLSKVTKEEAIRMAGNKLLEAGYVADGYVESMLYRENIMSTYMGSGVALPHGDRESEQLIIESGIVFLQFKEGIDFGDGN--IAEIVIASSGKGNNHLKILASLATLLKRDEILNTFTSSNSVDEIYEILRNN- -> -RGVLSLGQVRIRTGPVTKEDALHEAADILESAGAVTSGYLDAMYQREQAVSTYMGGELAIPHGTSETAHLILESALSFVRYDDGIDWDGDL--V-TFVVGIAGKGDEHLQMLSRIALLFADPVEIARLKSAATPEELYDMVVED- -> -KEILSMENIKLNAQFKNKEEAIRYTGEILVANGYVQPNYVEKMLEREEVTSTFMGNFVAIPHGTEDSKDEVIETGISVVITPEGVSFGDGN--TVKILVGIAGKGDEHLEVLSKIAIVLSEEDNIESLVKSTSKEEIIRIFDEV- -> -PEVLCEQNILLNIESETKNEAIKRVGRLLVENGYVDEKYIKGMIKRNDDISTYIGNGVAIPHGMNEYVKYIKYSGIVIAQYPHGVDFGEGN--IAYLVIGIAGKGDDHMSILSKIAIACQDKKNVQKLVEENDKNVMINLILEG- -> -MSILSKEKILLSAAAKDKYEAIRIAGELLVKAGHVEPAYVDRMIDRENIVSTYMGNGLAIPHGTKEGKDLIHSTGLSIVRFPDGVDFDGDE--PAFVVIGIAGAGGDHMQILTNVAMIFSEDESLEQVMNAPTEEAIMAIFEGG- -> --MYIPIERIIVNQQFASAEIALQEIGAYLVQQGIVAEPYVDSLLRRQQQYGVYIGNFVALPHAEEQAHQWIMEEGVFLFQVPDGVDFGTAA--EATILFVVVLKE-KQLSFLQEIAFFCSDIQNVRLLSDASSPQEIQQILLDE- -> -KEICSAASIVLNSKISERDEAIRAAGKLLVNGGYVSEKYIDLMLARERIASTYMGNHLAIPHGTDGAQSEIITSGISIIQLPDGVDFGGGE--LAYMVIGIAGKDGTHLDMLGQIAVACMEPDTVELMRRATSKQSIIDALGVA- -> ---MITEKQIMLSCSACSKEDAIRLVGQRMIELGFITAEYVNEMLEREKICSTYIANGIAIPHGLNNRSASILKEGMVIAQFPEGVYYDSE---RAYLLFSIAGCGERHLKILSAVADFIENNEVNQKLRTVSSLTPFYRMIEYF- -> -MEILKLDNITLSASFQDRDEAIKAAGRILVENGYVAPEYVDCMLQREAVISTYVGNNVAVPHGISGSEGFIKESGISVVVVPEGVQYSEHD--VAKLIIGIAGRDGQHMDILGQIAMICSEQENVDEILQAKSAQEILEIFQKE- -> -MSILKAENIKIGASVGSKEEAIKLAGQVLADQGYVNEQYIDKMFAREELTSTYMGNLLAIPHGTEDAREDVTQSGLSILLLDHEIDWNGNP---VQLVIGIAGKGDEHLEILSKIAIACSEEDNVRALLQVKTAEDVLDFFSGV- -> -KKVLELENIKVNLNSVSKEEAIRFAGEHLLNLGYVQKEYIDSMLRRENNLTTYIGNHVAIPHGDTGSASLVKTTGIVFHHYKKGVDFGKEK--A-HFIIGIASKDNYHLEILANIAEIFSDADLVKSFLKKVTVEKVFKLLQGE- -> -IEYLPEKNIILSGKASNKEEAIKEVADILITNNYVSEEYLDKMYEREESVSTYIGNYLAIPHGVDSS-AYVNKTGLAFIRYDKPIDWDENK--V-YFVIGIASKNDNHIDILSKIAILFSDENNVDGLKAAKDEREIIETINSV- -> -EMEITFQDIELNMAFQTKEDSIRYAGRKLVERGYVVEPYIETMIQRDILTTTYIGNGVAIPHGTDEARDFILKSGIVVLQVPQGIEYN-GE--CATVIFGIAGKNNTHMDILSQIAIVCSNEDNVKRITNAESKEEIIQILNGK- -> -SEILKKENIYLNCELEDKEAVIRRIGEIFVKDGYATDQYTRAMLEKEKVFNTAIGSSLAIPHGIESMKDQVLQSGIVVMTFPQGLPWGEQE--IVKLVIGIAARGDEHIDILSNIATHCASEEETEKIIRSSRD-EIYEFFASV- -> -MELLEKKNIRINCQPKSKNEVIQSVGQMLFESGYVKKDYIAAMVEREKTFSTNIGNGIALPHGTENAKREIISSGIAVQVFPEGTEWGEE---KVQVVIGIAGVGDAHLDILAHIAEKLSDPSEVGCLVKSDEE-GVYRMLTGK- -> --MVLEKRNILLNQRPDTKENVIKRIGAIFSAEGYTDDNYTQAMLEKETIFNTYMGNFVALPHGIEAAKKDIRKTGIVLMTVPEGQEWDAAE--KPKVIIGVAAVGDEHLEILSKIALSFSDADGIDRLLGMSED-DISAIFEG-- -> --MNISNECTYFNLDSMQKMEAIKLAGEKLLENGFIEEAYIQSMLDKEKTDLTYIGNGIAIPHGLNDAKQYVKKSGIVLLHFPEGIDYDEN---KVFLMIGIAGKDDDHLEILQDIAIKLSEMDFVNSLLSSETKEEFITLFNS-- -> --SSLTADGIHLGRTATSRTDAIDQCGRALVELGAVEVEYLAAMHEREESLSTFIGEGVAIPHGTDQARQYVKRTTLVVLQFPNGVEWGGN---TAKVCVGIAANGSEQVGILSALAHVLMDSTKAEQLREARDAGTVLDLLQS-- -> --DLIQQAGIQLAAAASSSEEAVASCGQLLFELGAIETEYAAAMWEREQIFSSAIGMGFAIPHGTDESRKFVNFDQLVFLRLENPIMWGDE---EVYCVLGIASQGDAHVDILGNLAELIQDPAHLATLMNSNSPSEILDLLLS-- -> --QRLPRELFVPGFVAADRTEAIRSLGSLLIQHGIVDDGYVASAIERERLSSTLFAEGLAVPHAMGL---TARRTALAVAVSPDGVRWG-D---RARLVVFLAISPEQFQSLFDRLVELFADPTSLGRVVRSGTDYDAEDLFDA-- -> --SILQPSSVRLGLASVSKQEAIRMCAQVLVDCGAATEDYFAGMLAREQQISTYLGEGVAIPHGTNEARAHIRSAALGFLQFPDGIDWDGN---EVKVCIPIASASDEHLGILASLAEALMEPEAAERLRVTDSVAEVIDLLTP-- -> --PMLRKENILLNQPKADRESIIRRCGRMLVDSGYANERYIEGMVKRDNSFTTYIGNYIALPHGEEAYKVDIIATGIVVLAFPEGIDWQ-T---LAYLVIGIAAKGDEHIDIMGNVVDNLETGDDVEKLVREGTVEDVYKMLAG-- -> --DLLQLAGITLDATASSREEAVAICGAKLIELGAVSPEYAAAMWERELTFPSELGDGFAIPHGTDESRVFVNFDQLVFIRLQRPITWVNE---EVSVMVGIASAGDGHVEILGNLADLLMEEDKAEILRTSNNPEVIRDLIVK-- -> --DLLDPRAVLLHESAPDREAAVRRCGRALADVGAVAEPYVEAMLERERSLSTYVGEGVAIPHGTNASKGDVLRDAICVVRFPGGVDWDGE---HVTLCVGIAAKDNGHVPLLAALAEILLDPDRARALREATEVSDVIKELTA-- -> -NDVLVLKNILVNQKSVSKDAAIEKAGQLLVDGGYVLPEYIVAMKEREAQLTTYIGHGVAIPHGVGVAKDKILKSGISVIQYPDGIVFDDK---VAYLIVGIAGKGKEHLKILSNLAEFIIEEELLKELFSTEVATKLYSAFTR-- -> -FSCLKISDIRVQLPPMEKFDAIRLAGRMLVERGSVSEEYIEAMVEREKTVTTYLGEGVAIPHGVGTAKQYIKSTGLVVLQFAEGVAFEDG---SAKLLVGIAGLGEEHLPILQAVAHIIMKGDLLKELQETDDPEFILRTLTS-- -> -KPVLIKEAILVDQNITDLNQSIDLAGKLLLDNGYIDEEYIESMKEKEHPYTTYLGAGVAIPHGMSDGFKYIKHTGISVLQIPNGLNWLDE---KVYIIIAIAANSDEHMNVLASLSDALESEEDAQKLWTTNSVDKLFEILSN-- -> -MLTLNLSSIFLNQSAEDKLQVIELIGQKMVEVGYTTEAYTVGLKAREAISSTFLGNGIAIPHGTPDSRDAVQKTGVVILQFPQGVDWGEGD--KVFMAVGIAARSNEHLQILSGLTRVLDNDDLCGHLAKTGNPQDVIEAINPQ- -> --MQLSCADIHFDREIKTKDEALQRVVGRLTEAGHTTAAYLNGMRDREGQISTYLGNGIAIPHGTPQSRDAVLKTGVKVLACPQGVDWGEQQ--TAYLIVGIAAQDSEHLDILRQLTHAMSDERVPEAYQRTRAPQAVLEILAGI- -> -MFNLPENNIHLAAQATDKQQAIEMAAAALEQGGYVESGYLQGMLGREQQTSTFLGNGIAIPHGTLETRGLVKNTGVAVFQFPQGIEWGEGN--KAYVVIGIAARSDEHLSLLRQLTHVLGDEDTAAKLATLDDVKKFRAILMGEA -> -MLTINRSNYYLNCKAENKKDALRIISDEFIKSKNVTTDCFYALSKRENQISTYISNGVAIPHLSKDDRTIILKSDIKVFQFPQGVMWGESH--IVFITIAVLSNDNDHIDTLKALTPLIKNDVAIDILSVTKHVDDFDKILSR-- -> -IDDITINNLHLGCQAKNKAEVLSMVGRSFKEKGYVSQDCVAFLNEREQQVSTFLGNGITLPHLPKSATNIIVKKGVEIFQFPDGVIWDRSNSSVMFIAIGVIAKEKEHIDVLKQVASIFSDEIIANALSLISNKQDFLRILNR-- -> -MMKITADELTLGCRAKNRNEVLRQAAFELAARGCVDIGFSKALLDRENDVSTWIGAGLAMPHINRRDAGQIIRSGFHFLQYPEGVSWDKSH--VAFLVVVVAAKDGDHIAMLSGIADLLVNERKVMRLSMADSKTAFLNLLAD-- -> ---ILVAESVVLSGSSTSRDAAIDEAGQLLLARDAVDEGYLRAMHEREESVSTYMGSFLAIPHGTNAAKGHIRKSAVSFVRYPEGIDWNGK---EVKFVVGVAGVNNEHLHILSSIAKVFTDKAQVAQLEAATSAEEILEIFRK-- -> ---ILPASNVRMGLASVAKEDAIRQAGDVLVASGAADPAYIDGMLLREHQTSTFLGQGVAIPHGTNESRTHIRSAALGFLQFPDGVDWDGH---TVNVVIPIASNSDEHVSILAALASVLADKERSQRLRTARTPDEVISLLTP-- -> ---LFTPDHVLIGAQADDKWEAIQQVGGLLVRLGLVRDDYIDRMIERERVLSTFIGNGVALPHGVGAADPGILKPGVVIAQYPDGVTFDEGN--KAYLLIAVVG-GEQQMGLVSRIAFMIENPDTVQALVRAGSPLEMHRRVSA-- -> ---SIDRCSIQLGLESVSRAEALRAAGKLLVDQGFARESYADAIAERDRLASVYLGMGVAIPHGTRAASDAVIKTGVVLQQYPEGIDFDGE---KAYLLFGIAGRGSEHLKVLANICGILENEKVLAKLKTTDDIDWILKVLS--- -> ---VFVLDNIMLGMKADTKQEAIVAAGELLFKQGYINKPYIQGMLDREETTTTAIGFGVAIPHGSIATKKEVRETGIVFLQYPQGVSFGDE---IVHYVFGIAAAGDEHLEILAQIADIVEDEEKLETLKTTTDKQTVMSLLGL-- -> -MFVLEPKHVHMNLRAKDKATALQCLVNILVEDQLTTAEYLTGLEAREAQGATYLGQGIAIPHGTPQSREFIKETGIRLAHFPEGVVWDGEH--KIYLAVVIAAKSDEHLQVLQILTRALNHD-VSIQVQTATTAEQIIDILQVR- -> -MLTLTPEDIRLGCQAADWREALSLASQELEKAGRTTPEYHQGLLDRENQSSTVLGNGIAIPHGTPDSREYVRSTGIRVLQFPEGITWHDGA--KVHVLVTIAAQSDEHLDILRHLTRVLDKPGLAERLANATDRNELLAALSRT- -> -MFPMTTQDIKMNQTLASKQAAIVALSRWLEQDGYVKAGYEAGMLEREAQAATYLGQGIAIPHGTRECRHLVQKTGIKALHVPEGIDWDDGE--KAYLILGIAASSGEHLALLRQLARVLSRDDLAETVRKAQHGEDIFNLLHEY- -> -TLSLEPKQILLKQSLASKTEVLTLISDTMQTLGFVTGDYTKALADREAKVSTYLVNGVAIPHGTNEAKSQVKKTGLVIVQVPAGVTWNDQG-DQAHFIVGIAANGDEHLGVLQQLTQVVMDEAKAKHLGSNANVQDIVQALNTN- -> -MIRLTTENVQLNTQVTTKAEAIQQVGTLLAKAGHIQPGYIDSLFAREAIANTYLGNGIAIPHGQPEHRDLIVNTGVAVVQIPNGVTWNAGE--TVYLVVGIAARSDEHLNILTNLTHVLDDPARVERLAHTKNAQEIVDELMVT- -> -PVLVASELVRVDAQARDKADAIAQAAQLLVAAGCVPPAYAASMLRREALANTFLGRGVAIPHCTGDDRHLVQRDGIAVLQLRDGVEWNPGQ--TTHLVVAIAAQSDTHITLLRRLTRLIQDQPRLDALFASDDPQAIVDALSQD- -> ---VLRKENILVNCPVETSDEAILSVGKMLVDGGYVTPEYIQGMMERDHSLSVFMGNTLAIPHGEYEYKKFIKHSGIVIKVYPQAIDWHGE---KVHLVLGLAGIGEDHINILSNCATVFSEMSDVERVIQNQDVEEIFNLLTAE- -> --VQV----------------LAPLTGVMVPIESVPDPVFAQKMVGDGFSIDPFDGTVFAPVSGEIADLQNA--HHALTIRTPEGIEILIGR--G-HVARGDVAAGDKLITF--DVDRVAREAKLLTQVVANMDA------IASI- -> --VAITESLVRLGLTARDKEDAIRQTAAILAEEGSVGAGYGDSMLARERQVPTYLGSGIAIPHGMRGDAAMVRRTAVAVAQFPQGVPWGDGQ--TVHLAIGIAAQSDEHVQVLAALTGVLQEPELAEALGRTRDKGEILRALGGA- -> -MFKLTKKDIHLNQSATGKIQAIKSIAQALVDADLVEDGYSEEIQQCEQQAASYLDNGIAIIST-TVFRHLIKKAGVQIFHFPQGIVWGENG-KLAYIVISIAANSDEQLTFLDKLTRNISKDGIEEKIKNIKTVEDVINILTGK- -> -DLKLTIDDIRIISGCYSKQDAIQSVSEAMIKAGLVKDDYTQAMFDRDTQISTFLGNGIAIPHGTTDKRDSVIKTGLKIIYYPKGVLWDQDD-NIAYVVIGIAAKANEHLDILRQLTKAVIAEDTLDRIKTIKTAENLLEILQGS- -> ---ILKKENIKINQSAKNKVEAIKQCGELLKELGYIEESYIESMIEREKKFSVYIGNYLAIPHGMNET--GVIKDGIVVIHYNEPIDYDGS---PVNFFIGIAAKSNNHVDILANIAEKMMELDFVEELIAKPSKDRILEEF---- -> ---IFSPENVLINQNAKTKEEAILQCGNLLKELGYINDEYIDSMLERERHFSTYIGNWIAICHGMDGR--GVLDNGIVIIHFEKPIMFEDQ---PTHFLVGLAAKNSQYNDFFEKMSIKLLEIDFVEELLKHPSRERIFKEF---- -> ---VLARDRILIHGVAQDREGAIAEAGQLLVDSGVVDASYVDAMHQRERSVSTYMGNLLAVPHGSSEATPAIKRTGISFVRYPDGVSWKGE---EVKYVVGIAGKGEDHVTLIGKIAEVFLSEEHLAKLAAAQTQDDILALFGS-- -> ---QIKDEFIFIDEDLKSKEDIFSFLENVLIKGEIGNKDFIDSMKQRDKTASVAIGNYLAIPHCDYSFSSNIKKQELVFIKLKNKVMWDEN---EVLFVIALILKNEGQLEILANIGITFSDEDLVLEFHKLTKKEQVNKFIEEN- -> ---YLNTNNILIGVDIKNKNDAFNKVFECLKKQNAIEDKYLNSMIERDKNSSVAIGNFIAIAHGTVETKDLIKKDAMCILVLKNPIDWDGN---EVKVVLGLALSGDKTMDVIGNIGVAFSDEEEVKNFYKDLTSNEVLKWLVAH- -> ---IKNKESVFLIDKFNSKIEAIEFVGNKMVELGYVDKQYIDSMIERDKTASVAIGNYLAIPHGNSDGFKYIKNSGILVVKLKEALTWDDE---KVNWIVALALEGNNQLEALQNLAIAFSEKSEVESMNKLNTLDEIFDFFSNL- -> ---IKSKDCVFIVDSFKDKNKAMEFVGSKMVELNYIDKEYIDFIKQRDQLASVAIGNYLAIPHGSLTGEKFIKNQGIIIVKLNKTMNWDNE---KVNWIIGLSLLGDKQLEMLQTIAILFEDINKVEQLTKLNTIDQIYEFFTNL- -> ---KISQENVLVDLNFANKNEVLNFIGAEFSKRNWTKPEYTQSLINRDQADSVAIGSYLALVHGQQQDCDLILQEGVLVIRLANSLQWDQQ---VVKWVIGLALKGDNQLEFLQNIAIAFSDEADALKVYQNTSVKQICDYFNNL- -> ---ILKRENIFLNQELNSKKEVFDFVFKIFFNNNSVKKQYLKSMIKRDENSSVALGNYLVLPHGEADSEKYILKNDVCIVHLKNELIWDNQ---KTKIIFALALKGDTQMEFIQIAGISFSDEQKVKELVKNINKEDIINFLKNI- -> ---KLLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGLKDVINIDGQ---PIKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVDDLTQDKVLEFLAKH- -> ---NLKLENIHLNQIITSKKQAFEKLIRIFQQKNCCEFEYLQSMEKRDLESSVALGNFLALPHGNFEGNNLIFRNCIEIIHLKNTLNWDGQ---PVKFVIGLAVKNSEQIDYIQKIGLAFIDVEKVEEILDDLSKQKILDWIINN- -> ---NLKVENILLNQVITSKKQAFETLIKIFMKKNCCNLEYLESMEKRDFESSVALGNYLALVHGTYEGSGLVFQNCMQIIHLKNTLEWDGQ---HIKFIIGLAVKSSEQINYIQKIGLAFIQKEKVESIMDYLTKEKILVWINTS- -> ---KNIYKKIYLNKTFNSKQECLDYLKELLKQEN-VSLEYIDSINKREEDCSFNIGSKIAIPHGIYEGMLSLKNSLIVVIHLQKPLIWDNS---EVQLVIGLALKQEDQIDMLQNIAINAMNDDLFNDLLN-PTIDKVISFCTKQ- -> ---MIKLENIKINKNFKDKYEIFRVAEEDLINLNSVKKGYQQAMINRDKSVSVSLGNYLFLPHGEDGSQDLILKNEVLVYHLKDVISIGDN---EIKVVVVLALKASNQMEYIEKIGIAFSDIDEVEKVMDQVTAQKIFDFLTQE- -> ------MQSVKMNCSYKNKKEALKAIINDLKEKG-VSEKYLNSIYTREKMASFNIGYKIAIPHGTYEESKNISETWLVIHHLKKPIFWDDS---LVQIVVGIAIKNQDQIDLLSNLAINAMNETFYEDLLK-PTEEKLNKLIIAE- -> ------KENIFLNQEFKTKQECLDYLKSIFKKEN-IDDRYIESIDLREQVCSFNIGSKIAIPHGTYDGMLYLKNSLITVLHLQKPIIWDDS---EVQLIIGLALKQEDQIDILSKIAINAMNDELFEDLLN-PTVDKIIDFSTKE- -> -KGVITTDLIFLDSDLDNQEEAIQHIVDTAEFVGYVEDTLFQAVMKREDEVPTAIGYDIAIPHGKT---EAVLKPFIAFLRVKQPFQWAKENEEMVRLVFLIGVPQKMHLKFISQLSKKLLDDDFRNKLLKETDKHKIYEHLSS-- -> -AEVLVKEAVILAGNVASKQMVFACLASQFKKAGVIRDEYIKSLEERESIGSTFMGNFIALPHGRS---ETVIRPGIGFLRCKEPFRYQSFDE--ERYVFMLAVSKNEHLRVLASLARLLAHREFIEKLEQVETYEELLAIVKT-- -> -ID-IDKNSIMIDVQETSKERLLSKMVERLDNCKLLLEEAEHSIMAREKLMSTGVGNGVAIPHSKT---NSVKSITLTIATVKNGINYKSPDNKKVFVIFMLLSPKD-NLKVLTSIAAILRDTHFIEKLINAEKSDDILELIAK-- -> -SRILTPRRVNLNLQASSKEEAIIELTDLLFSDGAISQAFIKDVWLREAEGSTGFENHIAIPHGKS---SAVKQTTLAIGRSQQDIPWETLDGSQVRCIILFAVRLTPIFACCPRWPVRWPMMRMIAQLLVENDPSEIIRLFSQ-- -> -TEMITINTVEFNLNLKTQGEVLEKITDILFKDNRIEKETLKGYIDRENECTTGIGFGLAIPHCKV---ESVIKPTIVCLKLNQAIDWNSLDEEPVNIIIGLAIPKTLHLEILGKLASNLMEDDFKRTLFNINDKNKLVTFLQE-- -> -KTVISTDLIFLDSELKQQAEVLSFIIETAEFVGYVADELYEAVKRREEEIPTAIGYDIAMPHGKT---DAVVHPFIAFLRTKEPFQWTTKNEEMVRLVFLIGVPKKLHLKFISQLSKKLLDTEFRAKLLIETDKNKIFEQLSS-- -> -RKLIEKELVLLDMALSTRDDVLTAVSDKAYALNFIKAAFIDGVLEREGLIPTSIGFKVAIPHVKS---KVVNSPFVSFVRTTEAFRWDDRNDEDVDFIFLIAIPENLHLRFLSAISRKLVDEEFRNSLRNAKTSTEAYDILQA-- -> -SKVLNVNHIKLNMVAKTKKEALEELTDLLVQDGSVIDEFLRDIWLREEQGATGFENHIAIPHGQS---SAVRHTTLAIGRTPHKIPWETMDGIDIHCIILYAVRSTTHIRLLTQVSCALADERIIAQLLEESDPKNIIEMFNA-- -> -AEVLLDEMVILCEPFKDKDDMFDAMTRKFEEAGFVSKAYKEALEYRETLGPTYMGNFVAIPHGKC---KEVIKPGIGFCRCKEPFIYESAGE--SKYIFVLAISDDYHLRVLATLAGMLAHEEFLELLGTAESYEDLIHGISN-- -> -LLFDEKLIVFPEDSFAAKEDVIRCLTHLE--NSRVLDRYEQAVLEREASFATYTIDGVAMPHAKS---EGVGEAFVAFARLKTPVPWGTESGEDARVVFLIGVPQNLHLKILAALSKKLIHESFRQKLSEAASEKEVYQLLQE-- -> -MGINVETKVILNNKYTDKKSFFAELCEVIHNMDEKVITIKEALEEREKVVTTGFGNELAIPHGKV---EGLISPYLFFVRVKNPIEWQAMDDEKVKFIFVILVPSNNHLKVLSILSYNLMDSEYQKMIKTVKDEEEAKNIIEK-- -> --MFSEKQVVFLEEAFPRKQEVIHHLTHLA--NERILDRYEQAVLAREESFPTYTIDGVAMPHAKS---DAIGEAFVAFARLKTPVHWGSEEGEDASVVFLIGVPENLHLKILAALSKKLIHDSFRQSLSEAQSVQEVYQLLQE-- -> -KEVIKKEYIFTGMEVTTKEEALRAIAERAVELGLCREETYQGFMERESQGPTGMQDGFAIPHTRC---ESVIQTGIVVMKSTRELEWESFDGKPVQIMIALIVPKNEHIQILASLSRMLMKQDFRRKLTETDSAEEIFEVIHQ-- -> --MLIARENIFLNKNFSSKGEIFQFLSQQAVERGWAAEKIEADLWTRENQYSTGFEGQIAIPHAKT---INVTEAGVIFIRLQQALDWESLDDSPIKIVFGLFVPELLHLKIINSLASQIVEDDFRQQLFDAKSEDELFNYMQS-- -> -EELINDELIFTAQDFKTKDEIIEFMSQRMHMLGRLNQTYIQSVHDREKCFPTCIGFGIAIPHGKS---EGVKTPTVAFMNLKQEIMWNEE--EEVNLIFLLAVPVNYHLKVLAELSKKLIEEDFRERLKNLGDKKEICNMLTF-- -> -QTILPEKNIILESGCRSKDEVIAYAAELVLGDCSGREKLKQEIWERERLAYTGIGSHIALVHAES---VTVDCPVTACIRLKKYIDWAPGKAKMVKLVFVFAVPK--ETEVLKDMVRKLGKKETVDRLMRAEQSREIIGIFQ--- -> -MSIFSTEMIVLHLDARDKQDALMQLAKRIEAAGQVGDNFMLSLNKREEEFSTAVGYDYAIPHGKS---DAVAVPAVAYAHLTQPILWDEEDEDWVENLFMIAVPADEHIKILTKLATAIMDDDFREHISQAKEPNQVIDIIEK-- -> ---MIDEGLIVLDSALTNKKSIIHYLSEKAKEFGYLKANYIKAVNKREEEFSTAIGYDVSIPHGKS---KEVINPFICFLRTNQPIQWDTNG-NTVELVFMLGIPETFHLKVLAEISKKLLDEGFRNDLLTGSKE-SILDSLYQ-- -> -SSIVNKECIVFDIDTDSKDEVIYTLVKKLKEQNKIKEDFYKNVLAREAIEPTAIGHDIGLPHGRT---NGVIEPAICFGRLKKPLVWSEKTGELGEVILMIAVPENTHMKIISKLARKLMHDDFRDKLLTGDKT-TIYKLLKE-- -> -MNHLSPAFIELNLKLKNKDDAISLLVDKLDENGCLKKKYLDAVLERENLLSTYCGHNIAIPHAVS---KAVKKVSFGFCRT-TNLEWDKKD-ESVQFILILALPDNYHIDLMSQIASLALEEEVREVWVNAKTEEDISKTFHQ-- -> -MTTLTANCIDLNIQGNSVYAILKQLADMAFQNGYVSSIFLQTLLLREKLHSTGFGSGIAVPHGKS---ACIRQPFVLFARKSENVDWKASDGEDVNCWICLGVPQDDQVKIIGTLCRKIIHQDFIDQLKQGDAS-QVLALLNQ-- -> -NDLITKEMILLDLDVNTKGEVIEKLAQVLQVHDRLHGGFIDQVHKREETFPTSLGYNFAIPHGKC---NAVKTAALAFARLNKEVQWSDE--EKAKYVFLIAVSEDTHLKILAQLSRSIMREEFREKLEASTSVHDIINLLSF-- -> -MKYIEKDNIIFNLKIEDKENAIKYLANVFNKNGYLNSKYIEEVNKREETMSTSIGKGIAIPHGKT---NAVNKPGIVVAKLSKPFIWDEVENEEISIIIMFAA-DNTHLKMLADVSMKLMDDDFVEKLKTSKNKEELYKLLRG-- -> -MKLINENLILLDMNLQSKDDIISCIADTLENNQRLCQQYIDDVYSREDEISTAMGSSIAIPHALS---LGVRHTSLVFLRLQNPIQWDND---QVQMVFGIAVRKNEHLRILSNLARKLMDLGFTNALLHSDNPDGCLQLLEE-- -> -MALITEKDIFLSENLSTRNEVLKRLAEISVEAGISDDDVYNAYLEREEVGSTGMINGFSIPHAKS---DSIKKPKILFLRNAQQSDWETLDENPVEVIISFLIPKEEHLRNLATVSKKLMKAENVNILKTTDDKAEIMGVLSA-- -> ----LTLQQIFF-QHFLEKEEVLSEIAILAE--KLGIGNIYDELKKREEEYSTAIGHGLAIPHAKT---DLIHSPAILFFKLEQVIDWS---GDEVCMIIAILTPRI-HLSILSRLSRKLMHREFRERLEAAQTQQEVFDLFRL-- -> ---MINQQLIFIDIDAHTKEEVFEYIAKVAVNNGIVNSIIIEGLHYRESLSTTGMIDGFAIPHAEV---ADLKESVVIIIKLKEEIDWESLDGEKIKFIVAMLVDKKEHLTTLSTIAKILMKQENRDLLHKANNQEEIYTIFEK-- -> -MALINANRILLNKTMKNKNEAIKEMAKLFVEDGVVDDEYLKSLMDREAIAETAVGYEVGLPHGKS---TAVKYPAVAFARLSKDIMWSEEEQETAKFIFMLAIPTNEHINILVNLSKKILDDDFRELLSKSNDVEEIMNAINN-- -> -VSSINPQNILVSIDDTDKKSVIAKLVDALYETGEITKEFIDDVYFREEEGITGIGNGLAIPHGRN---EFVKNSSFAIATLKQSVEWGSIDDEPVKVVILLADSL-GKPIMLDKFMKKLSDEDKLHFLKEATSVSDVISVLDR-- -> -MLTLNKDLIIFCENMNNKERIITKITSLLYRKNYINKDFVKKVIEREKAGSTYIGNNVAIPHGES---KSVKTNCLVILKSRLPINWDGYV---VHVIALFSIHP-IEKENYKRYIQAIGDENFVNKLKNTNDKEKIVMLFEN-- -> -------MIVKYNINCKDKYEVLSSIASIARENNNVRKLYLEGLIKREEQFTTGFGNSVAIPHCKG---EFVQESCIIVMKLENKIDWNSLDNKAVNIIIAFAVAENKYLVDISKIAKHLMDVEFINQIQECNTKDELEKSLLS-- -> -QDYISEELIQLDIQAEMREEIIDRLAELMEKKEVMAEDFLSHVFERERNGTTAIGSEIAIPHGAS---KEVQTPAIAFARLTRPIYWDNG--QPVSHVFLVAAPED----LYASLKERLQDQQAQELLKSAKTPQEIVSALQA-- -> --HVISPRLVSLNMSFSDKQEAIKKLTELLYANGNINQLFLRDVYLREEEGSTCIGQGVAIPHGKS---EAVVKTAVAIGVAQNTIPWEGAEEQEVNIVILFAVQNTKHILMLQQIAILLADDAFITGLHNVESREEVIELVQ--- -> --DAIKRKLIKTNMNVTTKDEAFSELVSLLKNEGFVSGGFIKDIYLRESEGQTGIGNYIAIPHGKS---SHVTEPAVVIGINSSEIPWETLDDNGVKVIVLFAVGNQEHLKILSLFARKLGNDQIVEKLINAKNEDDVIEAFS--- -> --GLITEDNILIDCNVSSKEEAIDKLAELLVELGAVSPGFLKDIYERESRGFTFAGDYLAIPHGWS---KHVVRTAAVVLKTKDSIVWDEKGN-LVKLIIMFVIPEGQGLKMIGQLFSSLGDVEAVKKLLDADTKKEIARLIC--- -> --DVLPLELIDVSMKATSREEVLEAFADMFEQAGCLSAQFLKDAWWREGEGPTGIGDGIAIPHSKS---EGVSKTSLAVARIPEAVEWPSLDDGPCRAFVMFAVRSQ-EVHLLSKVAVALCHKEVVETLLTSDDPKTIRCALS--- -> --LQLEKELLKLNMDVTTKEEALLTMIDMFFQNGNIEEVFKQAVYEREAIGETGMENFIAIPHGKS---RTVKYPSVAIARNKKTIYWENIDGNQARLIFLLAVPDTEHLRLLSTLARALAYKEVQDKMLQIENEEDLYDYFS--- -> --SVLNEQRIDLHLKGQTKDEVLDEMVDLLFKDSVLSEQFLKDVYYREGEGITGIGDGIAIPHGKS---DSVLHTAVAIGRSDHDLEWRSIDDKPVRLIIMLAIKSTVHMKLLSNVATSLCQRDVIEQIFVSEDKQEIIELFE--- -> --EVLLDEMVILDEPFKDKDDMFNVMTRQFETAGLVSGAFKKALEFRETLGPTYMGNMIAIPHGKC---KEVLTPGIGFCRCREPFIYESGGEGEVKYIFVLAISEDYHLRVLATLAGFLAHDEFLALLEKAESYDDLIKGIK--- -> --TIINKDLMIINSDANSKEAILEDLCSLLKNKQYIEQQFLEDIYLRESEGITGIGDGIAIPHGKS---GSVGETTVAIATLKNKIAWETLDEEPVEVVILFAVKDTTHIILLQKVATLLARESFINAIKQINNKEELYDLII--- -> --KILHEDDILIPMQADSKEEAIRQLAEMLKAHEVVMDAFMSDVFLREAEGVTGIGDYIAIPHGKS---KGVKENRIAVGILQEPIYWESIDELPVKVVILFAVCAQSHLSMMAAVAKSLAYDDVKQRLYEAESRQDVMEAIL--- -> --DILDENIIRIGIDAKDKDDALHKMAGLLYENQYIDEGFVKDVYAREAEGETGLGQGVAIPHGES---KNAQKLGVAIVTLNHPIEWETLDGGKVDTIFLFCVSSRNHMLLLSKIAARLADDDLLKQIRVASSSCEMIALLA--- -> -----MKESIDLNEKYISKEELFKEITKLLHNNNCIENKFLEELLYRESLGSTAIGNEFAIPHATYE--KGANIPCIIVCKLKYSIKWDDAGKFFVKNIILFANPKKKGLKLMASICRTLANEEICIKMSNMKCSKEMANFIY--- -> --EIIDPNIIKTQLIGTNKDEVLRELASMLLENGYISDGFIQDIYAREAEGQTGIGNYIAIPHGKS---RFVTKVGVAIGVTEHEIPWETLDGKGVKGIILFVVGDQNHLKLLSLFARKLGNDEVVEQLIQAKDAKQVVAAFV--- -> --EVINENAVAVNVKAQNKEEVFECVCDLLLKDGSITEEFKQDLYIRESQGKTGIGDGIAIPHGKS---LAVKRNCISVLKLEQPIQWETLDGLPAQVFIIFAINQDYFLRLMASVAKKLAQEGTCGKLMGSSTKEDILEAFC--- -> ----MDRKNVIINLDLKNQDDVLDYLSKKACELDIAIESIKTDLINREKVMSTALIEPLAIPHSKS---KNVLKNTIIFLRLNDFIDWSDSK---VN--IIIGIFSGEHINTLANLSRKLIDKEFLKFLQTA-SEDEIYENLK--- -> --DLMSKEIVMFDVDAKDRNEVINLIADAMDKDGRLIEGYVADVMKREAGSSTAVGFSVATPHSKS---VHVKEPSLAFVRLSHPMKWDDSE--EVELIFQIGVPSDRHLEILAGLFRKVMHDDFREKLFSAKTADEVIELIGA-- -> --DLINENLIYLNFDAADKEAVLSGLAKIISEEKKLEEGYIGSLHEREETFSTAVGFSFAIPHGKC---KYVKQACLAYARLNNEISWA--E--DAKHIFMIGVSENEHLEILIKLSTAILEDDFREKLNKAETESEVMKLLKD-- -> --PII-KENILFDVDAKDKADMIEQMVEVFDKEGYLSEQFHKDVLAREEVFSTYIGFGIGIPHGKS---SGAIDAGLCVAKPKNPVVWAD----DVDFIIMIAVSDELHLQLLSKLSRLMMHEDFRNELKNGS-KEEVYETLIK-- -> --DLINQHLIKINTTLNTKSEIFETVCKLLEADNRLLQLFLNDLYEREGAGATAPGYSFAIPHAKS---KGVKTASLVFIHLENEIGWT--K--SVKYIFAIAVPYDEHLNILAMLARKMMNEDFRKELNAAKTKEEYYRLLTA-- -> --ALVD----FTNQTFQDKEEVIRYIAEMVWENKKIEQAYINAVLKREQTASTEMGDQIAIPHGES---DTVRECFVAVLKLAKPVVWD-----QVALVFNIGISKKEHIEILARLCTNLMVEEDREKLYDAKNREELCDVLKS-- -> -SQFCRSELVNFSLESTTKKEVIREMVKLAAQSELVLEKLYQDTMEREKLLSTGIGFGVAFPHART---EAVKGLVIAFGRSDAGIDFDALDGAFVHMLFLVAVPKTTHITVIAQLSLILKEPVNREKLMNAVFPQEVIDLLNT-- -> -RTVLTTDTVDLHLKGTTKEAIIDEMLELLVKAGKVTAAARECVLDRERKMSTGMKHGIAIPHGKT---DTVSDLVACIGISDNPVDFDSLDQEPCRIFIMTLSPVGPHLQFLAEVSLLFKSPEKRQLILETQDKAEVIRILTE-- -> -PPALLQRERIINLAAEDKSKAIKELVDLLARHPAVTDELFRAVQQRERDMSTAMGCGCAMPHAKV---ASVRDFIMAVGLSRKGIPFEADDGTPAHIVVLIAGPLRRYLKILGQVSAVLADDARREGILTAMTADAVYEAFKD-- -> -KMIIHESLIDLNVLSKDKDEIIGDLACKAEKLGRISVGYLQAVFAREELFSTAIGYGIAIPYGKS---SCVKKPFIAFAKSNKAFTWDSRSEQKVRFIFLIGVPEELHLKIAANISRSLMNDSYRERLVQATSTRKIVAIFGE-- -> -VEVIRPDTVDLDKGITCKEEAIHYLAGLLNEAGLINDAYIQSVYERESLGPTYMENFIAIPHGKC---AAVREAGIAFGRSPEGFEYLTQDGGLAKLVFLLAIPEDAYIAVLAQLARLLVHDEFRAKLMEAKCYQDVFEAIAE-- -> -TGYLNRKNIFLKFSAADKHDAIAKLVGMLSTDDAIAEEYLASVFEREELGTTGLGDSVAMPHGKC---SAVSRMSIALAKLEKPLDFESVDKKPVDYIFLIASPLTLYIKVMASIIRSVKIHKICEKMNVLDSAEEIYEMLLK-- -> -IDILKQEYIKIPLFSTSKEEVVRELIDILTPFSIYEDLVYSAIMAREAIMTTGVGKGVAIPHCKK---NECKEFAIALGIHPQGVDYQSIDGKPAQIFFLLIGPEGMHIRLLSRISRLISKDMLREKLLSCSSASEAYHLIKT-- -> -VLRYLREDRILLHMAKKKAEGLRELAALVEDSAEIPRKFLSAVFQKESRFGSGVGEGVALPHYRD---EKVKEPVICMGVSEKGIDWGEK--EQVHILVLVAWPY-NYLKTVAEIARLLRLAPVREKIRNAGGPSEVLAAMQT-- -> -MKIIEKNLIHLDLAGTDKKEFLNSLCECLHREGVVDEEFFQAIWEREESFSTGIGRNIAIPHGKS---SVVKELKILVGLIPAGIEYESLDSEPVNLIFMFAVPPDRYRVLLGKISAFTREDANRLELLASKTKEEILTIMSR-- -> -LQELLKKSNFLEIEVKDKFEVLKTLVEDAKLDEYLKKEFLKKLIERERLISTGIGYKVAVPHAHS---EEVKDYFIILGYSKEGVDFDSIDGLPVHLFILIGTPG-TYLKILSEISRMIKNTKDV---STLDSKERIIQVFSE-- -> -REVIDENTVNLELEANDRDSVIRELAKMLNHNGLIQECFIQSVLEREKICSTYSTSELAVPHGIS---PSVRKAGLCFGRLTSAIDWDGDQETPVRYVFLIAIPQNRHLEMISSIAVSALQEDNLEKWGKVKD-------AEE-- -> -LCRLIGKNGICQLSKTNKSQAILELISHARQFANKPDDFYCEVMRKELLQSTGLGKGIAVAHGTC---QGIDQVYVALGISQEGIEYDAIDSQPVHLLFLVANPP-EYLSALSTLVRLLRNDSFREKIMHCVTAEQVYLLFKQ-- -> -SDFVCFEATIAELQSSRRDDVIIELVSSLEKAGQLKEEIIKAVIKRENEASTGMGKGIALPHVKH---PSVKDVIAAIGKSSIGIDFSALDKQPVYLVILLISPVDKHLQAMENIFKVLQQEKFRKFLRQSRNAEDIEDLLRE-- -> -ADYIKVDTINLNLESKNKSSIIKELYNNLKKTNLIKELGLNDIFARQEMGSTGIGRKIALPHAKT---KAVDELIATFGISRNGIDYESLDNENVNIFFMFLCPEQEYLKVLARISRLIRKDRFIDNLLKAGSNKEIIEIIRD-- -> -HNLLTQDMIILELESENAEGILREMVRFLR-KDIVSKELYEKLVQREKLGSTAIGEGIAIPHCKI---KRVKNPVVMLAISKKSVDFCSLDGKPSNIFFMVVSSPSINLQILAAIAHLVRKSGSLAKKILAKNISAVMDVIRE-- -> -EDILNKQRTCVFLSGQNKNDIIAELIGLMVKDGLISRELLDSAMEREGLMSTGIGKGVAIPHGRA---KGLKKMAGAFGLCRSKIDFGSLDGQPVQIFFFIATPQADHVKALALVSRLLNREEIRARLLAADDPQKVMDIFTE-- -> -SEMLKTNAINLRLKSRTKRDTLVEMVELLETGHGFNGEILDRVMRREAMMTTGIGNGVAIPHGKA---RSVDRMAAACGVAPEGIDFESEDGQPTYLFVLFVSPETLHVRVLANISRLLKEETVRKALREAKSPEAFLTVLQS-- -> -STKIKKSAILLDMKATNKDEALKELVDLLCSAYSLDDEILEAIRKREKKQSTGIGMGLALPHAKT---AAVDKLYVAFGRSNTGLDFDCPTGEKAHLFFILVSPLGPHIKALAGISRMIKHEDFRTALMTVKNEDEFIEIVKE-- -> -SERFVDNCILINSSSETKEAILNELVDTLCSAYKLEDEIFEAIWSREQSRSTGIGCGLAVPHAKI---DYVDRMCMVAATIEKGLDFQSFDGEPVYLLILIVSPGGPHLKALSSVSRLLADGNVRKDLIASKTPAEFLSILRA-- -> -SERFTDNSVIINSQSSTKEQILNELVDALCASYKLEDEIFDAVWKREQTRSTGIGCGLAVPHAKI---DYVDRMCMVAATVEKGIDFDAMDNEPVHLLILIVSPGGPHLKALSSVSRILANAEVRKDLIEAKTQADFLEIFGR-- -> -TEVMNENLMILDLESENKDGTINEMINLLEKENLLNAEYLKDVLKREKASSTNLVEGLAMPHAKS---KGVKNPAVVFARSINGISWDHEE-KNVKVVFLIAVPEDDHLIILSTLAKCFMHDNFFDNLVEAKTRTGIINVIED-- -> -ADILQPDRMKIPLVAADRRGAIDELVDVLADRGDVSEGIKEAVWQREQIRTTGIGHGIAIPHAKS---ACCEKLVLAVGVPDEPIDFDAVDGQPVRVIFLLISAVGPHIQALATISRILTDSNLRASITEVASAQQLHKLLVE-- -> -SEILLEKCVVADIKGKTKREIITELVEALEKARLIEEAVVNVVMEREKLGSTGIGNGVAVPHGKL---KNISNIICALGRSPNGVDFDAVDRGPVHIFFLVLAPESLHLKILSRITKILRDQSLRKKVIKLSNTHDIYTSILE-- -> -TDLLHPDCIQVPLVCKNKQDAIFQLIDVLAQKHHLTQQLKDAVWERENTRTTGMGFNIAIPHGKT---SSCDKLIMGVGIPEEPLEFNSVDGQPVKLILLLISPAKEHIQVLSAVSRMLVVEDIREAFFRATAPSEVYELLQK-- -> -EEFLSEDLINLDFNPVNKEDALSKMVQMFKKENKIKTDFLNKIFKREKEGSTGFGRQIAVPHGKS---KTVKELSLAVARVKNGLKYNSLDGQKVKLIFMVADYEPQYLKLVSTLVSLLRDNNFRTKLIEAKNKNEFIDLFRK-- -> -CKRLSTDCILLDLHEQDKEQIIRKLVSALHEAHHLSEKLLVDIMAREELASTCLGSGCAVPHAHS---ETLSTSLLAAARITPPADLETPDGHPISLVFLLVGPSVVHLKLLSKLARLLHDEVFRHQLLASDCAEAFHALICK-- -> -SEILNEKCIILNSELNDKDEIIEKLVELATKSGNITSKVLEEVFVRENLMSTGIGNNIAIPHTKS---EDIKELTAAMITLSKPVNFDSLDGKKVSIVFLILSNSGLHIKALSKISKILNNRSFFGDILNVSKNAEVIELFDN-- -> -TQLITADRIVNLNKEATKEAAIKTLVRCLS-TKFVSKELAKAISDRERILSTGIGQGIAIPHAKI---PTVSGFVAALGISKNGVPFDSLDGKPANVIVMIAGPEEEYLRILARFTSILKPEETRNRIIEAKKGAQVMGILQE-- -> -SSYLSLDLIKLHLNANTKEEMLKEMALLVK--DKVTDKFYEALLDRESAGSTAMENGLCIPHTRN---SYVKEFCIAVGTKEEGIDCSSIDGKKSTVFFLIISNDLEHLDALVKISRVVNDEIATMVLSSTKSKEGFIELIKK-- -> -MDLIG-SNINLHSKARTKEEAILELCDMLEKSGYIRKLFHDDVYKREALGLTGMENGIAIPHGES---SAALKAGIAVLKTSNPLDWESLDGKPITLVFLLVVPTTAYIKMLGHLAAALAYSDIQKRLSEESDSDK-FKEILE-- -> -TDFITPDCIVHHLQATDAQGAITELVHHLAATGRIDETIIEAVWAREQQRSTGIGDGIAVPHGRC---EHMDQIVAAIGTADPAIDFQASDGKAVNLVVLLVSPTTLHVQALGAISRRLGHAEIRRRLRNCPDAGCVYDVLCR-- -> -VSMIDERLVKFDFHVLDKNDAISKIGQLMFEAGKINDMYVNGVFEREKEHSTGIGMGIAIPHCKS---DCVREVAFTLIKLCDSIEWDAFDDQRVEYIIMLAAPNNLHLKMLSQLAVCLTDDDFRKSLLNSKTVDEVKQCLNN-- -> -MSKLVNVKCSFEMKATSKEEAIISLVDVVSKEGYLKNQFLEDVLKREETLSTYIGHGIGLPHSQS---IGVKDSCITIGKLDTSIEWTEE-GEKVDLIFLISVAKNLHLKILSKLARLLMHESFRNQIRESDEQT-VYNLIKE-- -> -NKIIREERINLNLEATTKAEAIDELAEILVKTNSVSAGFIRDVYAREEIGETGMGGYIAIPHGKS---KYVENTAIAIGRTKEILEWESLDGKGVKFILLFAVPETVHIKLLSQVASTLGDEEVCARLLTVESADDILEIMTN-- -> -SNLTNENLINLQLKGKDKIEIIKELASLMEKENKLIAQYLQDVYKREDEYSTAFERGIAIPHGKS---HGVRESCIAIGK-CNKVKWSHEDNCPVEIVILMAVPKDEHLAILSKLAEMLMEDEFIEELKKAATSNEVLNMLKN-- -> -LEYFNSKLITYINGKHTKEEVLKILVDLIRETDVLKQHFYENIMAREELGSTGIGQGIAIPHARS---EKIEEIVVAVGLVENKIDFNSPDGEGVNLILLVGAPKREYLSLVSELMRTFRNKKLREAVTCASNYQELLEAIAE-- -> -REILTEESIILDLKSTTKEGIIQELVDKLYDTGSITSKFIKALKHREKIGSTSIGYQMAMPHGKT---KYVKKASIVIGKSKKGVDWPSIDGLPVKVIIMFAMPQNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYE-- -> -MGKLINKNCIVFDIRGDKKDVIHRLAVELGKAGTITEEFYKDVLAREAISPTFVGFDMGLPHGKT---DHVLEASVCFGRTAEPVIWNEESGETADLIILIACPLDTHMKILANLSRKLMHEEFRESLRNSDEEQ-VYQILTE-- -> -RDILSEESIILDLKSTTKEGIIQELVDKLYDEGSITSKFIKALKHREKIGSTSIGYQMAMPHGKT---KYVKKASVVIGKSREGVDWPSIDGLPVKIIIMFSMPQNEDIILISKISYILGGKDISKKLLNAHTKKEILDVLYE-- -> -MSTINPNNISLHLECSDQEALLQKMTHWLFQSHAITAGFLEDVDYREMLGMTGIGNEVAVPHGSN---CVAY-PTVAIATLQAPIAWKSIDDAPVRLVLLFAEPDDAHNTLLTKMIRKLSNDETLYAVKQAATVDEIVNALKE-- -> -LI------VFSDTEYASKDAVIEGMA--ELVANKVDEGFANAVKEREAAFCTYIDHGVAIPHGKT---DIVKSPFVIYQRLGKGVTWGEDG-EVATHVFMIGVPENLHLRILAELSKGLVREAFRDRLLGTDSKEEVFEILKD-- -> -SDYLKEENIKMNLVAKNKEKAIKTLLEFNS-----LESILKEIMKREELESTGFGNGIAVPHARI---DGIPSITILVGVSKKGIEFDSLDGKPANLIFLILAPKKLYIYILAKLIKVLEEEKNLTELVNIDTPQSFIEKFRS-- -> -MALINGESINLNLQGSTKENILKEFAALGYQVGKVSEGFYQGLLDRESEVTTGFGYGVAIPHAKT---KYANEVGILFGRTNNQVEWQALDDKPVNTFICFIAPENEHLKLLAKISRKLMHQDFVAVLKNG-TKEQILQALET-- -> -LI------LFLDKEYKDKKELLTDLS--KAVDSKVTEDYEKAVKERENTISTFIGYETAIPHAKT---DAVKNPFVAYAKLSHAIDWDGNG-EMVKHIFMIGVPKNLHMRIISELSKNIMRNAWRESFMNAASADEALAILKL-- -> -MDILNNQTVFLNVEGSTKEAILQAVTQQLETSGYVKKHAYNDIMKREAEISTGFVSGIAIPHTQS---EAVEKTSISIIKPVNSLSWETMDDSDVDLIFLICVPLDEHLKILASLAEMLMDEDVIDALHQIENEDEIVDYIRR-- -> --MIIHESLIELHMKSKSKTEIIETLAHKAKELGYISEGYLQDVFALDESSPISFGYGIAIPYGKS---RYVLTPFIAFARSEEAFTWDHRVDHEARLIFLIGVPEDFDVKMLTHMIGGLTNESFRRRLLQTSDAAEVVELFKE-- -> -KKSLVAKAISLDLPSDKNEAIKVAIKALTK---LSLDEVFEAVMAREKALSTAIGLGVAIPHAKI---KSLKKFAYSIFCSEDPINFQAPDKTPVRIIVLLLSPEKEHVTLLAEISRRLKFSHVRQAILEAKTPKKVAEAFLQ-- -> -ENFINKDNIILDLETENKIEIINKMINTIS-NEKLAEKFFEDVLKREKMENTVVGFKVAIPHGKS---EFINSPQIVFAKLKKEIFWGDPD-EKVKYIFLLGVPS-EHIKILMKLSKKILEEKFREKLEITDEKEELLKIIIE-- -> -MLQIPESNIILNLKGTDKATVMKELLETI---QHIGEGILKAILARNKIMSQAPGRGVAILRYLG---TYARTTSLAVGIKREGINLDALDGRPVYIFFLLV-SN-KYVDILAGLLRLIQQPTIRLNLLRAHSKSQIRKILET-- -> --------------------MGIKELVDALDMDGRLACCVEDAVWKRESVYSTGLGYGVAIPHCQS---NDIYNDSIGVVRLKKPVDWDAIDGKPVDLIFLLTVRQENHMKFFASLARKLVNDVFLKQVRACTATDEML-DLLN-- -> --DVLNESLVEPGYRADSLEEVVEELLRLLDATGKVLELARRDLRENQQHLTAGMQHGIAIPHAKT---AAVKELLAAVVVTERPLDCQSVDGSLSQIFIMTLSPHGPHIRFLSEIGRLLKHRRVRRKLLEARDSGELLAVLQRA- -> --QYLVPERVWIKVEVANRNDLLAYLARQTAGCALVPQEFFKLLIHREEEMSTGVGRGLAVPHADP---PAMKSTFLAAATLASPIDYQSFDRVSVDVVFMIFGCPSLHLRLLARISRIARLPGFLDRLRQVQTTPDFLRVVEEA- -> --DLMDPKGILLYANIDNQADALGIMVELQESSGVITTAYYNAVCQRETFGTTAIGNGIALPHAGN---AGVSAPGISALTLRHGVDWGAPDGRAVDLIFMIAVPPSLHLQILARLVNLLEYGTLVDALRHASSPARFLELIQRA- -> --TVFTPSCAAVEVRAATKADAITALVDLLAAAGKAPAGLLAAVMAREALAPTGLGEDCAIPHAQT---DTVTETSIAAIRLAEPLDFGAPDGSSARLVFIIVGPKALHLRYLSRLARVLGDPDFHDAAFAASDAAAFVAAILAT- -> --DLLDKQCILLDMDCQDLQQILKSLLTTISEAHPQQAPMMEKVLTNPGFSTVCMGFGCAISHARC---TEMKKTFIAVARLSPPLDLGADDKLPVALFFLLVGPQLFHIKILSRIARLLHASEFRKGLLQAKTSEDFHQLICNK- -> --TLFSSSNILVRPGLSEKKAVLQAMIRQLEKSGTVTDQLLADVMEREKLAPTALGHGCAAPHAYS---DAITKTEITAAVLDKGIDFGASDGEPATLIFLMAGPKRLHLSMLSRLARLLHNQKMRNALKQVQNSGDFMELMSQW- -> --DVIVKQCILLKKDVQSKEDALHMLADCLNEEAYITSAFLKDIHKREEEFCTYVGHETAIPHAIS---ACVSKAGIAFLRSDKAFQYGSSDET-VKLLFMLAIPKEQHLRMLSALATKLMHKEFREQLLHAKSISDVYEILMLH- -> -SDLFTEDFILLDVDINSKDELFKAAAEHLYSKNIVNELFIKALYDRESIGETGVGDGFAIPHAKS---EAVNKPAVLYIKSNRKIEYESLDDLPIDNFFMLVVPENEHINLLSSVACLLLEDEFKAKLENVKSKLEIIDLVNKY- -> -GMDFTEENILLDVVVASQSELFKSVARYAEKLGFVKEKVYEAFVERESEYSTGLQDGFAIPHAKS---PYVLAPTVLFIRLENELEWETFDESRVKNIFALLVPETLHLEMLSRLATALMEDEFISQVQKNTNKDQLVTVIKNE- -> -SEIIKQEYIHLHCPAVTKAEVLQTASRWAAEAEIIAALFLKGLWDREAEFSTGVGDGIAIPHCRL---ESIRQPSVFFAHLENPVRWSP--EEEVDLILVLAVPSNTHIRLLSQLARKLVDEVFVSQLRELDQPAAIYALFNDI- -> -GAILNEKTFFLDIAFNDKDEMFVQLTRWYFEAGLITEVFKQALYEREALGSTYMGNEIALPHAKS---SVVKRPAVLFCRMREPFLYESSGETLVRFIFMLAVSEEAYIQMLASLAGLLANDEFLQKLRSLETLQEFLKYARDL- -> -SQLILEDLILFDDSIRSKKSLFECLGNMLESAGRIKKKIIRAFFKREAEVSTGIEDGFGIPHAKS---KYVLVPTVCFIHSGKITEYLGVDGIPIEYVFAIVVP-ASHLEILSMLSRQLVDSSFRKQIKEATSRKKIMTILKNI- -> -IDLMMSDLIIFNESISSKDELFEEIGRILEENQRVTRKVIKDLYKRELETSTGIEDGFGIPHAKS---KAVLKPTVCFAHTGKMDNYVGLDEKPIECVFAIIVP-EIHLEILSGLSRKLMDLEFRKQLKSATNAAEILEIINKE- -> -YMVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTEALLKDLLKRENEFPTGIKDGFAIPHTKS---VNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAPKNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNK- -> -ENVINRSCINLHMKGRDKKEVIEEMAEMFDRAGVLVAGYIKAVYERESEGPTGIGDQVAIPHGKT---AAVGKTAMAVGRLDKGIEWETLGEGTTRAFVMFAVNDSELVSLLSQVAIALCDEKVIETLLNTESEAEIFTLFNRK- -> -SSMIDTNCILFDSTIQLKKDLFSRLATILEKSGYISKRFIKDLEKREKESPTGMEDGFGIPHAKS---KTVKSPVIVFAHTGKIVDYIALDGSQVDCVFMLAVP-DIHLDILSYLARQLMNDDFKLELKQASNASDIQSLLMNK- -> -SKIFNESSIILGTTLKTKAEVFEKLASYFYKNNYCDEMMIQEFWNREAEGSTAFINGIGIPHAKA---EKINYPGICILKNNTGIEWDSLDGEDTSLFIALAIPKSIHLKMLSSVARKLADAEFKNNLLAAKSKKQIYELISSV- -> -MTIIHKENIFLQQPLDSQEEVFMFLAKQTFCLGIAHKEVYQKLLEREKEGTTGIMSGFAIPHAKS---QAINEPSLIIITLDKGIEWNSLDKQSVDFIFALFIPSTTHLKLLSLIARSLMRKEITEQLRVAKSKTEIATILIKE- -> -NNVISEESILLDIEASSKDEVFDIMSNNLYKLNRISEEFIKSLYEREALGETGVEMGLAIPHGKS---KFVLINSLSVARLNNPIEWETLDDCLVSIVVMFAVYQDEHLDLLAKVAGNLVEEDTIEFLKTSNDKIAIINK---L- -> --MEFRNENILLDVAVKDKLALFDYIADYAVTHQIVADALVEAFLKREREVSTGLQDSFAIPHAKA---AFINEPIVLFLKLSQPIEWETFDDKPVANVFALLVPEMVHLQMISQIATSLMEEAFTDIIKHTNDVTLLTKTISSA- -> -KEMIDPKLILFDERINTKEELFDQAARLFNSVGIVEKKYKKDLFIRENQTSTGIEDSFGIPHAKS---QAVTRPAIAFIKSGPISDYKAMDGTTVEYSFLIAAP-DEHLMILSSLARLLMHEEFRNKLKEAVTPKDIIDIIKTN- -> -KEFLIEKQIIV-TDLTTKQDFFKTIADLAFENNILSEEVILGLNERESKGSTGLLDGFAIPHAQT---PSIKKAAVVIVKSTNKVGWESLDGEPINTAICLLVPSTTHIDFLTEISKLLMDDDFRANLNKLNDSHSIYEAFLSQ- -> -NELLKPDYIIFNVEASTKGEAFRAISKIAFEKNITTQDFENGLWARENLDSTGFGHNLAIPHAKV---NSVTSAALIIVKFTNDIEWESLDDEPVKMAFVIAVPNNHHISILSQIARRLMHDEFTEALLLAKTPQEVEALVKNN- -> -MNLFEIDHIHLDLEVSSKDELFDFIANALKALGRITADFKKALEKRESEISTGLGEGLGMPHTLD---TSVMFPTMLYIRLKNEIDYQAIDGLPVKEIYAIAMPNKEHLELISKIATIYIDETSKQEIRALDTKESIHSFISKN- -> ---MILEKTVFLGETLHSKDEIFSFIAKQAYKLEIVHQVAVSDLKKREAEVSTGLQDGFAIPHCRT---ENVKKTAILFIRLDNEIKWETFDGKDVKNVFCILVPGAIHLQLISKIAVNLLEDEFKQKIATAKSTKEIVELINFE- -> -MEVFTKDNIYLDVHIDQKEDLLREIAEKICLLGYASEKVHKGLLDREKEFETALGEGFAIPHTKS---EYIKTPGIMIMKTTEPLSWSE--EENADVFIVLFTPENTHLKMLASLSRRLMNQDFKRILHESMDKDEIYNAVYEA- -> -MDIFKKDYIFLDIGLKDKENSIDFIAGKAVELSISNDQTKKDLWSRERAFNTAIDETIAIPHTKS---ESINLPAIFIIKSKNIIDWGG--K-NIKLIISFLTPENIHLTMLSKISRKLVDDKFKTTLNESDDINLIYELIMSA- -> ----IRKELVFVDEEVDSQSEAIEKLVHQAVQLQVIEESFLKAIYHREEEFSTAVGFGVAIPHGMS---DTVREAFVGFMKPKHTILWGNE-QKEVDLLFMIGVPEVIHLKLISQISKNLMKQEFREKLLACKNNDEAFQYLEK-- -> ----AKELTIFTDKVYHDKYEAIEDIAHL--PNEFVNDEYAKAVIARENVIATYIGYGIAIPHAIS---AAVNQAFVIYVKFLNGCPWANEDEDRVDHMMMIGVPATQHLKILAELSKNLMHEDFREKFLNTKSPEESYELLKS-- -> ----DEQLT-FVNKTFKDKLDAIDFLIQEAKAAGKITETYKKSVLQREAEFSTAVGYEVAIPHGAS---DDVTESFVAVSTIENPILWGE---ESVRMIFMIGVPEKEHLQILAWLSRNLMHDDFRSNIINATTETQLFECLSR-- -> ----IEKELIFLDDELTSRDEIVRKMSENVRKLGMITNAYMEAVLKREEKIPTTVGLNVSIPHGKS---EAVQHPFVTFMRTKNPIVWDERSDEKVKLIFMIGVPIKLHIKILAQISKNLIDETFRNRLLEASSTEEVYRLLKQ-- -> ----VPQAMILLDEEVENRDAAIHHLVSQAKEANLVNKQMEEAVLAREAEVSTAVGYQVAIPHGKS---EAVNRPFIGFLRLKDTMLWNDSD--EVKLIFLIGVPENIHLRFIAQLSKNLLNENFRAFISKESSQDKLYEFFKE-- -> ----VAEEMIFVNTSFNSQKDLFEFIADTAFGLGRTSKSVVDGFYHREGEYSTAMNDGIAIPHCRT---ESILDASVIIIRNSEKVIWTEDE--ECDLFFALLVPEQMHIRILAQVAQLLLEDEFVAQVRQANDPSYIFDLVKE-- -> ----IRKDMIFVDVSATNRDQVISKLSETAKALDLVDEDFIQAVMQREEEFPTSIGFKVAIPHGKT---KTVKEPFIGFCRTEQPFIWEQEGNKEVSLIFLIGVPQTLHLVILSQISRMLMNEDFRRKLSESKQKEDIYALLLD-- -> ----IHKEMVFLKQALSTKDDVIELLSDQAIKLDLINKDFKEAVYKREEMASTSIGYQIAIPHGIS---HTVNRAFIGFVQIKDAFHWNHDEKQSVQLIFLIGVPQNIHLKFISLLSRRLLDDNFRKQLIEVEDVEDAYRALNA-- -> ----YSERLIAVNLEADSKDSAIEQLICMLDKENRINSEFRDSIYERENESTTEVGEYTAIPHGRS---ETVIENSVCIATLKKPVIWNFETKEEIDIIFMLAVKKDTHIEILSELASKIMEEDFISNIKNSDSKNEIYKIITE-- -> ----FSKNRILLT-NTIEKDEMIDIMCQKLYEDQLITEIFKKEIYLREKEYPTYVGHGIAIPHALS---NTVQSAGVCFMKVAEGVNYEGGG--KAHLIFMLAAPEQTHLKMLSTISANLMHEENRIKLLEADTVADIYNVLSG-- -> ----EPEIVKVSSTRFETKEEIITYLSQKAGHAKKIKKSYVDAVLDRESTASTAVGFGIAIPHGES---DAVTETFVACLHLLHPVQWDH---DEVDLVFMIGVPLKEHLRILAMLSRHLMKEAFRKELRKIRTDQEFYECIKF-- -> -SDFVQASHVFLDNPAKNVDEALEFLSRKAVELGVADRAVLDAFKAREAEGTTGMMSGFAIPHAKS---AAVKEATVMVVKFAGDVEWESMDDKPIVVAIALLVPGTTHLQLLSKVAVMLMDEGFRNDVLGATDEASIAERINS-- -> -RELLQKKYIYLDVDLHTREEVFHFISKESFKLGLAEVAVGRSLAEREEQSSTGVLDGIAIPHAIS---ADIKVPAILFIRAKEGVDWQTIDNSQVKQVITMLVPKQEHLETLADLSGELVDEEQRKKLAACLSVDEVYDFLNQ-- -> -RPSFQVDHVIRDPDSTTRDQALRFIAQQMHQAGYVGDAFFSALVARETQDTTGFKDQIATPHAKS---KQVKHAGIWVVHFANEIPWETMDERPVKTAVAFAIPAETAMAPLIAISRANMKPTFREVLNHGDTVSIV-AAIED-- -> -SKFVSSDQILVQVDVDSREKALELISQKGVELGFGDKSIYDAFIAREEQGATGMEHGFAVPHAKC---DVINKAGILLLKLVKPVEWPSFDDQPVDVALALLVPGTTHLKLLSKAAVMLMDEKFRDAVRATDDTQALADLINA-- -> -WNCLHTKRIFLDVPLPDKDAVLQFVAEAFASRGIVKDSLYDGLKAREDTMSTGIGRGIGLPHAMS---NDTHDAAVLLVRCSEPVDFESLDAVPVKVIVALVVPEDLHLQMLASLARLCQYPGFFKTVQDAKDPKALFDSIKQ-- -> -SKIIQADFIQLQATETSQLGVFRKIAAIAMEKGIASEEVVTGLKEREAQSTTGFQDGFAIPHTQC---AGILKPAIVIVRTETGIEWESFDDQPAFFFIALLIPKSTHLQALSSLSRVLMDDNKRQELLEAQTNEKLAALVEK-- -> -TSILDIQHITFDSSVTTKDEALQFIADFAKEKEIVKKAYYKGLKKREQEVTTGFKSSIAIPHCKH---KTVKKPALMLVKFTNPIEWESMDHQPVHMTFALAIPEQEHLTLLSTISRALIDEAFTKSIMEAATAEELHAIIQN-- -> -TEIFKQDYIFLKEHLKTRDEAFEFIAKQAVTLKFADDAILKALYKRENEASTGMQDGIAIPHAIS---VHLQQPAVLFVRSTTAIDWPTFDDQPVDQIIAMLVPKQAHLEILANFASALVEDEERQALLKSQTVSEVYNVLTT-- -> -KEIFNINHVFTDVIANSKKQAFEIIALKFYLLGFTTNKALKGLKKREKEGSTGFNDGIAIPHAKI---KEITKPGVFVFKFKNGVEWDSIDNSLVTIAIALAIPENDHLKILSSIARKLVDDDFRKDLNKANNVDQLYQLISK-- -> -TALIKKEHIYLQETLSSQAEAFDRVAQVAYESGAAQQAVIHGLAQREAESTTGFIEGFAIPHAKL---KDITEASVIIIQNQMGIEWNALDQNPVTFIIALLIPDSTHLNLLSSVSRMLVHEDARQQLIKASSPDDILNTFSS-- -> -IDLYNPRMVRVGLPGQTKAEVFRSMATLFVETGKVTERFVEDLQTRERSISTGVGRGLAIPHGKS---EAVSTATYAIATLRDPFLWDEDDEETTKLVVMLGVPATTHLRLLSEFATALMDDEFRAELINAEDEADIRSALAS-- -> ---MMENLFVYTNVAANTCEAVFAFLSTKIVEVGKATQAVEIGLKQREAEGTTGMMDGFAIPHAKS---ESIEEPTIIILKLTNAVAWDSLDGQPIKYVIALFIPATSHLALLSQMARMLMDEGFKQAFITASTQEEIVGLIDS-- -> -SNILAPENISLNETAASQADVFQLIAEKAGELGITAGAVVTGLAEREKQGTTGLMDGIAIPHAKS---ASITDAALVVVRLRESVEWESLDGNPISMAISLLIPETTHLKLLSQVARTLIKPAVRAQLLAAETPEAVVEILGQ-- -> -TNIFNKEYVFLNVDAKSKVEVLKFISKKAKELNLAESLVYEGLMSREEQFTTNLGESIAIPHTKN---DAIENPAVVVLKFNEDVVWNEG-EDKVKLAISLLMPGNIHLKLLSSLSRKLINKDFKDSLLKSDNVEEISNLINE-- -> -PDFIQESNIFPEQSLADRDGVLRFISDRAADLGITDDGTYEAFQYRESLDMTGMLEGFAIPHAKC---ACIKRAAVIMVKNDRPVAWPSFDDVDCDIFIALLVPETTHIKLLSKTAVLLTKDEFRKKVRETDDSAEIARMINE-- -> --MLLQENQIFLDIELSNRDDVLDLISSKAQELGVIEETLVQDLISRENKYSTAFQEGIAIPHAKS---ETVNKAALFFIKMNQKIDWNSPDQFKVRFIFAILVPTTRHLQILSALAGNLMEEDFQESLSTIETKEDVMNLLKS-- -> -SEVFTKNHIKINLDLKDKDAYLRYIAKLSIELGIGKQGVYEGLVSREKEFATNLGDGIAIPHTKS---DYIIKPAILILKPQKEVSWGNVAEEDVRIIISILSFNNTHLELLASLARKLVDEKFKNALVNSVDEEEIFFLIEQ-- -> -MVLVSAQHVFIEVALDTKTSALQFLAESARKLQLTTSAVLTSFNDREKEGSTGMMDGFAIPHAKN---PTIKEASVLIVKAKKPIEWDSLDGQLTEVIIALLIPETIHLKLLSKVARLLMKTEFKQQLKHLESSAEIATYVNQ-- -> -KSVFDRHHIHFDTEAKTQKEAFRVIAHEAFTAGFVKNAYYEGMCAREEEATTGFQDGIAIPHSKN---ETCIKPGIFLVKFKHAIEWNALDGKPVQVALGLTIPEEQHLRILSKLARKMISEEFRTALKTGTDVDALYEVIAA-- -> -MGIDIQKSIIIDVSALTQQEVFNLISKEAVSNGYADTLLLKALNEREAEGTTGMMDGFAIPHAKS---KTIKKPAMVIFKLTEGVEWNSMDGKKIEFVISLMIPETTHLQLLSKVARLLMKNDVKQLLKNANSASEIDSIFTR-- -> -IKIIIPEQIVFDVDASSQKEVFSKIADLAKQQNFIHKKLIKAFKKREKESTTGFGDGFAIPHART---KDILKPGVFFIRLNQGVEWNALDGNPVKIVIALIVPTDTHLDLLSKIAQKIVKPDIQKVLSDSKDPKQVIKALIA-- -> -MELISKELIDLNQSCSSKQEVFEQAAAIAFQHGRITEKVVEGLFQREAQTSTGMIDGFAIPHTQN---EAVKVPSIIILRNAADIEWETMDDSNVRFVLAILIPKNLHLKILSAISRKLMDERYRKFLLAAESRTEVVDLLEG-- -> ---MLNKQLVFCNKNLINQKEVFEFLAEITTKNQIAKNQIFDSLKKRELEGTTGLMDGFAIPHVNS---IDILEPTIVIIKLQKGIEWDSLDGKLTNYIISFFIPKNKHLKFMANIARMLMLSDFKEEFKRAKYKKEIIEVIEK-- -> ----------MVGCALTSRDGALHALSARAVELGIAEQALVEAFLQRENEGTTGMMDGFAIPHAKA---STIKRRAVLVAKSNSAISWETMDGEPVSVIVALLVPETDHLRMLANMAEALMDSRFRSMLRRSDDPREIAAEVNR-- -> ---NFTEENILLNVERATKEELLQFISEYALEIGVATKEVMEDFLQREKEVSTGFTHGIAIPHAKS---VAVTKCFVLYIRTKEGIDWGTLDESAVTDVFAVFVPKALHLKVISSLAEELIEPEFIEVIRCLNTSSELANYLNK-- -> ---EFTLDNILLNCHAKEKKELLSIIADHAERIGVSTRALFTDFIAREEEGMTGLQDGFAIPHAKS---SAVNQVTVFYVRNESLFDWETFDEQGVKHIFALLVPITKHIEMLSKLATALMEDHFKQKVSNSMNEQELADVIEQ-- -> ---NFSQENVFLNVSESSINSLLKYISEVAVITGYTTKALNKSFIDREKEFSTGLEDGFAIPHAKT---AAVKKAGFLYFRLANPLKWQTYDDQPVTDVFALMVPPNEHLKMLANLSTALLEHDFKKELRRMTNRNEIANFINE-- -> ---MITREQIYLDKKLETKSAVFEFITQEAEKLGVTVEQLVQDLWEREKVYSTGLQDQFAIPHTQS---EAVTRPAVLIIRLQDSIDWASHDGKPVQYIFSILVPKVSHLQIISSLATLLLEDSFKEAVAGAKSSDDVYHLLEQ-- -> ---IFSEDTVMLRLDVEDKDDVLRQMGKKIEATGCLKEHFMAAIRKREVEFSTAVGYDFAIPHGKS---DAVALPVVAFARLARPVLWDAEEDDRAQYVFMIAVPADEHIRILMKLAGAIMEDDFRDQIAAAKDEAQVIEIMTR-- -> ---MLNRNYIFTDISVSKSEKNLAKIAELLA-GPMNLDELLDGLLKREKEGTTGFTDGLAIPHATL---QSLADPKVGVVTFDTPIEWDSLDGKGVRTAFVLLTPDNIHLKMLSQLSRNLMKEDFVKQIQDNLNGDNLFKIVSS-- -> ---MITTDQIYLDQSLPNKEDVFQFISAEAERYHITSEQLEADLWEREQVYSTGLQDHFAIPHTQS---EAVTRPAVMVIRLNEPIDWESHDGKPVKYIFVILVPKVSHLRIISSLATLLLEDSFKEGIAAAAKPEDVYGLLHQ-- -> ---KFSANDVYLDVNEQSVDSFLKYASQVACNAGFAASELEQSFLAREQEYPTGLEDGFAIPHAKT---ETVKRPGFIYFRLTTPLDWQTYDDKPVTDVFALMVPPDEHLKMLASLSTALLEDDFKQQLRQLTSKEEIANFINQ-- -> ---LLSPELIFLEKEFDTKDDVMNFIGDVSVKFNITDEALVRDLWQREKEYSTGLAESVALPHTKS---DAVMEARICFIRLKNEVDWNSLDGKDVKYVFGILMPSNLHLKVIASLATNLLEDEFKEKLESLETAEEFYQYFTN-- -> ---KFSADDVFLDVNEASVEDFLQYAAKAAYDAGYTNEKLDQSFLAREQEFSTGLEDGFAIPHAKT---TAVKKPGFLYFRLSQPLNWKTYDKKPVTDVFALMVPPDKHLQMLANLSTALLEKDFKEKLRNLSSKEMIAQFINE-- -> -MAMFTINNMNMSLEGHTQAEILVSLAELATSLNLVVDSLVKDYQEREQESTTGFGNGIAIPHAKS---NNVKTAAILFGRSTTDIEWQSLDGKPVNTFISLLVPADVHLKLLAQLSRKLVHQDFVEILKR-GDTREVLEIINQ-- -> -ISLFQKDHVFTQVNGRSKNEILQYISEKAEDLQITNAGLLADLLTREDEVSTGLQQGFAIPHTKS---SAVQTASLLFLELEQPIEWGSFDDLPTSYLFTLLVPLVTHLKLLSGIATSLMEPAFIEKIQPGQTADYYYEVIEQ-- -> -TSIFQKNHIKLNIDIRHKEETLRYLAELALDVGVSHVQTYESMLKREGEFTTGFGEGFAIPHAKC---ASIVKPGVFLVKLKSPIDWNAIDGEPVSLIIGLLTPASIHLTLLASLSRKLMEEDFKKRFFLSHDQDELFNLITE-- -> --MLIDRESIFLNKAFTSKDEVFDFIASHAVAQGWAVNDIKTDLWQREHEYSTGFESQIAMPHAKT---DNVIKAGVIFIRLNDAIEWQSLDGEPIKIIFALLVPKLLHLKIINALASQIVDDDFRRALFTLENRDALFQFMVQ-- -> -MTLFSQDHMLGTLQAANQAEVFQALANRAQELGVVASAIIADYTQREDEATTGFGGGIAIPHAKS---AQVLTATVLFAKLDPAVDWDAIDDKPVDTVISLLVPLAEHLKLLSALSRRLVYPEFVQVLKN-GSTDEVYELIAS-- -> -MPMIDKNLINLEVNVATQKEMFHYLADLAFQEDRAKAAIEQGLNEREAESTTGFGKHIAIPHTKN---SAVKEPTVIMVRNQEPLEWDSLDGQPVETIINLLVPDDTHLKMLAKLSRQMMHADFTDVLKT-GTKEEILTMLTK-- -> -MALITYADIDLNISGNTQYAVLKSLSQMAVARGFVNARYLQTLLLREKESSTSFGCGVAIPHGKS---AVVHQPFVLFARSAQGVDWQAEDGELASCWICLGVPQSEQIGMISKLCRKVIYPDFIAQIKS-LDSAGIVTLLNA-- -> -NEIFAEENIFFIEEGLDKNTFLKIVAEKAAEKELVSEACIKGLLEREQQQTTGFQEGFAIPHCKN---DTVYSPKLMYFKT-APIPWDSLDGNPITDSFVLLIPEDEHLKYLALLSRALIDDEFRSGIKASQTQNEIYRL----- -> --MILENNQIFLDEKLSNKDNVMLFIAEKSKLLGITDKEIYNKLWEREKEYPTAVQDLIAVPHVKS---DLIKTAKLLFIRLTEAVDWDSPDGFKVKSVFVILVPEQKHLEILSKVAVSLLEEDFQSMILNMKTGDELIKY----- -> -MKLLSINNIHCNISANTKEDVFQIIAKIAVENGYAIDKVVKGLLEREAESTTGFLEGFAIPHTKN---ETIQHPGIIVQTMEKGVEWESLDSLPARFIIALLIPDTAHLKYLSTIAKMLMHKEVRDQLIQAEKEQQIYDI----- -> ---MLKQENVILDVNASSKEALFESISKVALETGVVAGAFVEGLKAREAVSSTGFMDGFAIPHCKS---ATVKDPAVFFIRLQEGIEWGLTDNTSAQYMFCLAISDGSQLKVLSKLSRKLVHADFRSQLKTADSSADIV-E----- -> -------EMVRLDPPLSTPEEVIEYCGNILVENKKAKAGYVKEMIDQRFGPYMVMAPGLALPHARPG--GNVKEPCISFVKLKEPVCFHHPCNDPVWVVFALGGVSDGHIELLQDLSSLLAGERMIEKLAALNTYEELEKLMEKE- -> -------PLAAVNVEAKDWQDAIRACGKLFIADGATEERFSDAMIRKEFGPYIVVAPGIALPHARPE--DGVIKASMAVVKLKTPVNFGNKDNDPVWLLVALAAIDQGHIQGLADLASVLGDSANVEKLKKCQTAAELLDVFYSA- -> -------NRIALQVEVNSPEEAIQFGGNLLKADGLINHSYIQAMLDRDQGPYFVIAPGIAFPHARPE--EGALKTGFSLVIFKRPIVFSHPSNDPVQLMLCLSATDQKHLTALMQLAQLLQSEATKEKWLQARDKEDILADLRHL- -> -------SRIALQVELDSPEAAIQFGGNLLEASDLITQAYTQAMLDHKQGPYFVIAPGIAFPHARPE--EGALATGFSLVTFKTPIVFSHPSNDPVHLMLCLSATDQKHLEALMRLAELLQSEALKQKWFQANDKETILADLNDL- -> -------NNTQIISKTDDWKSAVAFAVQPLIDSGAAESRYLQAIYDREIGPYYVLGEGIAMPHARPE--EGVNRTALSLVIVSEGVEFGSEGNDPVYVIFALAAVDHSHIEMIASLSHLFCDDEAAERLKRSKNKQEALEIIRQF- -> -------NLVAFNVKVDTPEEAIRKAGKLLADQNHVDCSYIEAMVRKDNGPYFVLAPQVALPHARPE--DGVKEASVSLVQLAEPIEFGNELNDPVKLVFALGASNDEHLEILKKLIGLLGNKETIQRIIDAKTYEEIEILIKGV- -> -------SYIQLDVEAENFEEAVKRSFDPLIEDGAVTDNYVESVLRRETGPYIVITKNIALPHAPVE--DGANKLGLGFVRLKAPVVSGHATNDPVKYLFPLSAKANEHIELLSKLADLLSQESFIEFLENVSSKEAFISYFNNQ- -> -------EQIELDVEVESPVDAIRAAGNLLVKTESASSDYVDAMVAEKLGPYIVLAPHIAIPHARPE--HGVKKQCMSIVRLKKPIKFGHPANDDVSLVIAIGGVDNFHIKMLQALSELLTDEDKLKRLKTSTDKAEILCTINKE- -> -------SSIALDLEAESAEDAIRLAGSLLCNTGAIEESYIDAMIDREKGPYFVLAPHIALPHARAQ--DGVKEPCVSLLRLNHPVPFGHTVNDPVQLVFALGGSTSEHIQMLRKLTTLLSSPGVVEDLQNAPDVDSVQQILRRN- -> -------QAINVDCAANCPEEAIREAGEALCRAGACSPQYVQAMVDRELGPYFVIAPGLALPHARPQ--QGARKAQISAIRLHEPLAFGHAENDPVQVVLGLSATSDAHIHLIQHIVTVLSDENNLHTLMHSRDPEQLYQLLASG- -> -------KLIRLNIDAKDWEDAVRQAADALLQNGKIKSSYIEAIIKKEGGPYFVLTKHVALPHARPE--AGVIESAIGIATLKEPVVFGNKENDPVKYLFCLSALDESHINALADLTGLLERKKFYEFLDQAKDASEVMQYIKSL- -> -------VRVSLDDGSLTPENAIRAAGQLLVDDGLAEPRYSEAMIGRDLGPYIVLVPGIAMPHARPE--AGAIRDGLAVLRLAQPVEFGHPENDPVRLVIPLVGSDHSHIDLLKRLSRVLMDPEAVNTLLTTDDTAAVTALFNGL- -> -------SAILPQADLTTSEAAIQVSGHLLVRNDYADKSYVTAMLESKNGNYIVIAPGIAIPHAAPG--SMVHHQGLSLVTLKHPLNFGHPLNDPVCLVFGFCAPDEGHLDMLMDLAALLEQPQYVTRIQNAATKEEILQIISE-- -> -------EHVAVGVQAKDWERAIEASGSLLVKSGAVTSEYVKQMVDKENGPYIVIGPGMAMAHARPS--EAVHTDAVSLAVLKEAVPFGNEENDPVDLVFSFSATGESHLHLIERLSRLLLDEEKVGQLREAKSAEDVYQIIS--- -> -------ELVNLHGSAKNADEAIEQAGELLVNAGYVSEQYVEKMVEHENGAYFVIAPQIAIPHARPT--DGVENSAVSLVVLKEGVNFGHAANDPVRLVFGLAATSEAHLKVIQKIVSLLSNSDNIEKMIHSEDYQAIGELVEG-- -> -------QAILIDNPASTAADAIQAAGQALCLSGACSQEYVEAMVAREFGPYFVIAPGLAMPHARPE--QGAIKAQLSLVRLREPVAFGHTENDPVQVLLGLSATSERHIQLIQHIVTLLSDENNLHTLMNSRDPEQLYQLIAGA- -> -------EHIITGIQVANWEEAIQASGDLLIKSGAVSTEYVKQMIQKDNGPYIVIGPGIAMAHARPS--EAVRENAISLAVLKEAVSFGHEENDPVDLVFSFSAKEDSHLKMMESLSRVLIDEQKVEQLRQAKTAKEIYQLL---- -> -------NAISTNQDYSTASTALHAAGTLLERGGFSNPAYTDAILDQHNGAYFVIAPGIALPHARPI---GVLKSGISILTLKTPLDFGNTANGPADLIVALAATGNDHLALLSQLVTTLSDRWRYQQLVAAESAAALYQLLE--- -> -TDNLKRQNIFLKAKSTNRWDLINEMVDLAAKNREVEDEIKKSLIDREKSMSTGIGNGVAIPHCTT---AKVQDIIIVISIIPRGLDFDSIDNQPVKIVILLLVPKTQHIKTLANIAKLMSNENLRNKLLAIKTPDGIIKTIKDF- -> -RDIVVEKAIIAPLKSTKRDDAIRELVEVLATQGAVKEELSKAVIKREKRGSTGFGHGVAAPHVKT---TEVQRVFVAVGIAPGGLEFQALDKQLVHVVFLLLSPEEEHIDAMECIFGVLTQDKFRRFLRQAKTPAEVWGLLEEA- -> -LTLLQPETVIFNLESGSKEEVISRLLQKAIDTHQIDEEILESLLAREKSMSTGIGSGVAIPHCSV---NLVDELKCVMGLNPNGIDFDSIDHQPVHIFILLIVPKQEHIKTLAQIAKALNVKEDREKLIRSGSFEEIQKAFSRN- -> -MDMVKNGGVLVGIEATEKEPAIDETLTAFCNRGKYSTKLKNAIMEREGTGSTGIGNGGAIPHCRI---GKQDEVQLYISVAKNDIEFQSIDGKPVKILFLIVLPKSLHSEALKAIASLMKNERFFRYLKEATSEEIILETIEDY- -> -GEILTKDQIIPSMKATTRWEAIEELIDLLVSCNKIRESIANVVKKRESSMSTGIGFGVGIPHAST---DLIYDVVGAFGRSQAGVNFDALDNKPVNLVMLFLVPQQKHLHTLANIAKILHNNDFRQSLEQASDADAMETLFKQQ- -> -KTYVHPECFIHDLAAKTREEALREIVSVAAAKGIIKAAVLERLLERERIQSTAVGSGIAIPHCFT---DEVADLVIVVARAPGGIAFDSFDGRPTHVVFLLMGNRGLHLKALARIARLIKSTAFIDRVVAADSVEGMVRAFEEE- -> -SSVLSPTSILLPIKSEERDSVIRELLEVMQFD--SEEKIYSAILEREAVSSTGIGEGVAIPHAKC---DIQEEMVIAFGITEKPVDFHAMDGKPVRIVFLLLSRKGPHIRMLANIARLMRNDRFAKKILLCKTRGEVLHLITEE- -> -LEILDPKNIIFDFKASTKEDAIRKMISHMVATQSLDEETVSSLMNREKSMSTGIGSGVAIPHCSV---HYVNELKCAMAIAPQGIDFDALDHGLVQIFIMLIVPKQDHIKTLALIAKTLNIPEEREKLIKAKNFEEIQKAFLSK- -> -LEILEPKNIIFDFEASSKEEAIRKMISHMVGTSSLDEDIITSLLNREKSMSTGIGSGVAIPHCSV---HYVNELKCSMAIAPKGIDFEALDHSLVQIFIMLIVPKQDHIKTLALIAKTLNIPEEREKLIKARNFEEIQKAFLSP- -> -SQYMSRER-ILDIETISKDDLLNKMADLISSDAK--IQMKRAIFEREKSMSTGIGNSIAIPHART---DSVTDFIVCFARIKDGVDYDALDQKPVNLVFMIVAPAKMYIKLLSRLVLRMKNDDFIQNLLDADTPERLFSLICDT- -> -KDIIPADRIFHYSSPADKYALLEDLMDRTLAG-TAFEKILEALLDRERSMSTGIGSGIAIPHCST---QHIEGMLASIAILNEKLPFEAVDDRPVGIVVLLLLSRDRHIKTLAAIARAFNQEKLRDAVAQTTTAEEVMALFEKM- -> -NKNL---------KAKDQIDVLYKIADIAKENKI--RTYLKGLLEREKQFSTGIGNGIAIPHCRC---DVVNEIEIIICALGEPIDWNSIDNEPVDLVIALAIPNNEYLSIISKLARLLMDENYVNELKSFKDEKDIIRKIKST- -> --MIFQKRNVKLNVLTHSKNDALKQIAKFAYDLGYTSQKLFEAFIKRENEVSTGFERGFAIPHAKT---SVVQQPQILFCRFVNPVDWIAIDHQLTKHVFVLLIPEHEHLEILSQVAKGLMKAEFISKLTTTDNAELIYYLI-T-- -> --NILNKDCVILDSQSQTKDQALLELAELGVKFKVVKQNLFEGFLKRESEFSTGLESGFAIPHAKI---SEIKKPMIFIVRYGSEIEWGTLDNSKVKVAIALMIPQSEHLALMSNISQRLLAAEVKKILKTSSDPQEIIEALSV-- -> --ELFNGNLVSFNQEFTSKNDTLQWIAKQLVTYGCANKQVFDGLIHRENQVSTGIGGGFAIPHVQN---DAITNNVVAFVKVK-PLDWNALDNQPVQYIFTIALNKNEHLQLIAQLSRLLLEDKFKTGLNEISTYEQLIDLVKT-- -> --LFFNWSQKTFKNKF----SFLKQAANALQKQAVINNVAFEALKKREEEITTGIITSLALPHLQS---QSVIEPFVAVFKVK-NLDWQSLDQKPVKLIFLIGVLVNLHLDFISNFSKLMLNETFASKVLNVTSYNGLIKLIDL-- -> --QVINNKKIFLDVDVETKTDLFKFAANQLYDLNLVSEKFVKALLNREELSPTGMGDNWAIPHGQD---DSVKAASVLYIRTKKPIVYESLEGNSADKFFFIAVPSSDHVKILSKIATLLMEDEFKKSMSNIKNKEDIMTLISN-- -> --EMINENLIKVGLKAKTKEEAIKELSQLLYANNKIKKDFEKDVLARERQMSTVFEDGIVMPHAKS---NSVNEASVAIGISKEGIDCNSVDGKKSRVFFVIAMPHDLHVKTLSEITSKLLDDSFKQTLFSAKNKGEVYNLFNE-- -> --DILTRDNIILNLQGNNQKEVIDELIHKLTERRLTTERFKKAIYKRENEISTAVGYGVVIPHAQC---KSITKPTIIMGRSLQGVDYG---GQHTNLIFMIAAPENEHLSLLSKLSTFLMSETFRAKIIVATSEIDVIKAIQE-- -> --NYLRPDCVALRQRADSLTGAVQQMVTLLNGTDNLTAVFAADVRARLALGGVCVGNGLAIPHAKS---TAVRQLQLAALTLDPPLPCDTPDGKPLDLLVMIAAPADLHVQVLAELATLFLDTDFCACLRESETPEAFCRAISA-- -> --ALTNTGLIVLNSDLDNKDDIIRTLARKLFESGKLTDAFLQAVYEREALGETGMGGGLALPHGKS---TAVKEACFAVMTTRAVQDWESFEDDGVRHIFLLAIPASTHLALLAKLMQNMGDEEYSERLFSAQTPELFYQYLDT-- -> --ETIERKNIIITKNIQNKEQLFHYLAEYMVSQKEIDEAFEQALWSREQLSVTGVGNDVAIPHVQK---EFITRPIVIFLKSETPIAYESIEGDSVRLIFMIAVPEAKHLNFLAELSRKLMDDDFRKHLLEASDVDALYHIISE-- -> --DLLSEDLVFINADFSDKKDFVEKAAEALAKKKLCTDAFVKDVFAREEQGDDLPEEGVAIPHAKS---SAIKKPKIVAATLSKPWAHP-DSDNGISMVFLLAMPKDDHISVLSSLSTLLLDENEVKALRAAKSPKEFIKLMHV-- -> --TLTHRDALCLNARFTSREEAIHALTQRLAALGKISEQFLEEVYRRESLGPTALGEGFGCAAWQNC--CGKRSGGLRVATLSEPLQWEGVDGPEVDLVVLLAIPPTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDD-- -> --KYLINDGIVLEPKISNKWLILEQLTGFFCRQL-LADQILETVLNREMIVSTGLGGGIAIPHART---DLVQKTELLFARFKSGVEWNSIDGSSVNFLFLVIGPTEEYLFVLSKISKLLSRKQNKELL-HAKSSKEIYMILSSN- -> --EILHRAVIKTDLEASTKDAAIAELVDSLIEAK-LLRKVLHALNARERSMSTGMEMGIALPHGTS---PDITNLVGALGISTAGIEWQCLDDQPANLIMLLVLPRQVHVRTLAGISHLLNEETFRTALINAPDADTILKLIRKE- -> --HLLPPSSVLVPLRAETKQEAFDELFAGISMLR-LIHGLKEAVLRRELEGNTGIGHGVAMAHGKL---QSLTDIFLCLGISMHGIEYGSYDGEPVRLLFVAANPPGVYLHMLAVLSRYLHLAAFRRII-NSEGHIARVLLHGAL- -> --EKLSSQNIVLNLKSDNKTDLIKELAERLKGHP-LFNQFVKDIFKREEDTSTGVGDGIAIPHART---NAVNDFVVAIGRRQPGIDFNAVDGQPVEVVIMMGTSLSLYLRLLAHLSHLLKRPGFNGLK-TAATPQEVIDLFFRY- -> --EILDVRAILPDIESDKSKEILKILVNLVCQVK-IKDEIVKTLIEREKLKSTGIEDGLAIPHGKF---PKLQNMIAAFGRSEKGVDFNSMDGKPTHFLVLILAPESIHLKSLARISRMFKDKEFRNKLLVTSDPEQIYKIFLDQ- -> --DYVPEN-NIFELKQTGKTEVLREITDRAKALS-LASEVFHQLLKREQLGSTGIVNGIAIPHCKT---DMIEPMSIFVGYSSEGIEFDAHDGNSVFLIFTVLTRKTIHLAALAAISRMISKYGLSNIS-DYLNPEALRRIIEEC- -> --GILKPECIVTDIKGGSKPEILGQLAQPV-----GQFLLTEVLMNRERLGSTGIGEGVAIPHGKV---PGLGAITVALGLSAAGLDFAALDGKPCHIFCAVLVPSSGHLKALARVSTLFKSGELRHRLLAAADAGEVYRLCALT- -> --DILKESRIVIDPTGGTKELALHVLAEVI-ATD-GVEEVEGPLLEREKLQSTGIGEGVAIPHCSL---QALHDQMAALLLSAHGIEFESIDNAPAQILFAVVSPKSDHLKILAKVSRLLRSPETRRLL-EATTSEQAYSLILEH- -> --DVLSPTKIQLRIPVTSKRELLDRLLAIVDAEG-LSERARQAVFEREERLSTGIGYGIAIPHAKT---DAVARATAALVTCAQPVEYDSLDGKPVDIAILILGRSRTHLQLLGKISRLVSSEQSRTLL-QARTPNAVYEYFQQL- -> --DLITDDLILADMKARDKRTAINEIVAFMCARN-IARKVEAAVLRREGRGTTGIGKGVAIPHAKN---CGQVDIVAAFGVARGGVPFAALDGEPVRLVFLVVSPRNDHLRVMRKIAHLARDDKT-RFL-ATTRDFSTLRALDEV- -> --ELMSTNRVAYRLTASDKEGVLKELVQRCFIQL-EQSGILEVLKERESLGSTGIGDGVAIPHGKF---PRLGHLAAGIGIHEGGVDFGALDGNESQFFVVLLAPEGQHLKALARIARLFRDAGFKRRLIDAQTTQELFDLIAQE- -> --EIIQKSLVCLNATESEGQEVITALIDKAAGLL-ARDTAVRAVLNREMSASTALPDGIALPHGRI---ECVRDIICMLGVHPAGIAFGAPDNQPTHVFVLLLVPACNHIHFLAKLSRRLMEASVRELL-AARTRDDVMRTILSN- -> --KLVARAGLIQELEASTKEAALQELLGAAQDVG-FRKTLQKRLSDREAIGSTGLGNSVAVPHVKG---DGVDEITLVVARCHPGIEWQAIDGRQVHVLFMLVSPMESHLKCLRWIAGLARNTDFRRFLLDADGDDAIRDLLVEM- -> --EYFSKKAIVSQLKASDKKGAIKELVQVVKDVY-PVNDIADDVIKREKLGSTGLGKGVAVPHAKV---VELKKVIGAFGRSTDGIDFDAVDGEPVHLIFLILSPIDLHLEALRKIMQAIKRPNFCKFLNSAKGIKDIEDIFVEY- -> --AYLSHDRIYLDMPLPDKASVLKFIAESFVRHK-AVDAVHDVLEKREKLMSTGIGGGIAIPHALS---SVIGEMVIVLIRLKPGIPFEALDRRPVDVVFGLAIPATCHLKALAGISALCKNPGMLTIR-SVVSPRMLWQQIEAV- -> --KVLSLDRIVVGVKNRDKIGILQELLEVAATSG-IKEELLKSLLQREQIQTTGVGFGLAIAHAKS---DDVEGVVLSVGLSEEGVDYDALDGKPAHIIFMLVSSPTEYLSVLAKIARIFREEDFREAVMHAGSPEKVMNLLKER- -> --EALNVSRITLDLQSGDKQAAIRELAQLAGDHG-LVAGYVESVIEREFLLSTGVGRGVAIPHAQS---GAATGLSCCLGVSRAGIDFESIDDEPVHIVCMIVAEEAAYLLLLSRISRLFAQRHVRQQVLRAASPEDLLAAIRAA- -> --EFIAASAILPDLKAETARGAIDEMVGQLVTIK-VRRKVVDAILRREKKGTTGFGNGVAIPHAKH---EGVKGVVGLVARSASGIDFAALDRQPVHLIFLLLSNPEQHLKAMEHIFRSIKNDNLRRFMCQASTRDELVDVLREA- -> --DILNESRTFFDVPGKNKQELIVNIVERAKASN-IVKKFTQEVLEREALGSTGIGDEVAIPHART---ENVNQLLMAFARAKEPIDFEAEDGLPVRLIFLMGVPIKSYLNILAKLSRVIKIQKVRVLS-QTNNPKEVIEIIKLA- -> --ELLNETTMKIDLEARNKSGAIEELVDLLVEEH-IRSHVIQAILQREEMVSTGMEYGVALPHGAV---SCVEEVVAALGVSKQGLDFQSIDGRLTYIIILLVLPKSAGVRTMAGISRVLTSDGLRDRLRAAGDAGEIMDIIIEE- -> --EYLDQRNVLLDIESPDRDALLRRLVECLVSTG-LVEEPLRRLIEREEVMSTGIHPGIAVPHAYT---GAAPKSVCALARLASGMDFRSLDGGKVFIVFCLLGPPEQHVRLLARIARLIEMPGVIDLR-MAATPDSLITLLRTA- -> --EVLLEENVNLDLKAGTKEEVFTQMTRMLYENG-IEQPFIDELVHREAEGVTGIGEGIAIPHGRS---AVVNRSVIAIGRTRTDVSWETFDDKPVRCIIMFAIRD-QHIMLLSHVAQLLLDKDVITLH-HARTVEEIVNILRKE- -> --DYTKVSLLKPRTGAVSKKKVIEELVQILAENK-IVSPVCKAVLKREALGSTGIGQGVALPHVKI---KGVKNISFVFTNSETGVEFNSLDGGPVNIIFLLIGPEEEYIKALSLLARNLNDPYFRRALAAAKNGKEVMCILKKT- -> --DILEPNAVITPLKGTSRDEILQELSTCL-ANH-EAEHIYDVLLSREKLNSTGIGDGIAVPHGRV---NGLDKVKGALGLSPEGIPFGDSEEERTHIFFVLLAPHGAHLKALARVCRLLKGTDLAKRLITLETSSAIYQTLSEK- -> --DVLERKTVIPNLQSRSKPDVIRELAENLASAY-NDEKLIEVLMEREKLCSTAVDSGVAIPHAKM---SGVSDIIAGFGRSIEGVDYDSLDSKLTHLFIILVAPEGAHIQLLARISKIFKNPELRARLMTLETQDEIYDSIIME- -> --EYLRLDQVIFNLKATDKIQALEELLDVLVKLN-IKKPVLTRIIDRERLVTTAIGHGIALPHARL---DTGGDIAVVVGRSVAGLDFEAVDDKKVHVIILIVWNPGLFNHLFAGLAQFLIKPGFRRIF-NARSKKELH------- -> --AFTGTKLVDLSLSARSKDDVLASMVGL-ARSP-VGARFLTDVLAREKLVTTGVGYGVAFPHAKS---AAVKKVVFAFARTAEDVPFEALDCNPVRLIFLIGAPRGVYLNLMARLSFLMKDEGNRALL-SAGTTKAVFDIFDSV- -> --QYLPPEQIFFFDHG-DRMEVIEKLCKGL---L-EIPAARSKILEREGEASTAIGKKVALPHASI---DALDDFILGVAVSPPITGWETFDMEPLHIVVMILAPSESYLEILSEISKKLGQRRVVEIL-KARTREEVAKIFHS-- -> --NLLSTETIVLSLKHSDKEGIIEELLDLAVKTG-VRKKALKALLDREDLGSTGLESGLAIPHART---NAVNGVALALGISKTGIDFQSADGKPSHLFFLLLAAESVNVQVLALIARMNLSSEFRSKMVSVDSAESALEIVRAM- -> --SLLEVRTIELDFAKRRRQHIVERLVEL-AGVH-LQGRLVREILQRDSEVSTAIGDGVAIPHKLT---PLVSQPQVAFLQTRKGGHFSSPDGIPVRLFFLLLAPENEHLRTLSKLARLLHDARFRELL-EATVPQAVVEMIRSR- -> --QLLNPSLVALNVRAAEKNGAISFLCDLISQ-N-KPEPLYTTIMNRESLQSTAVGHGVAIPHARC---DVT-DFIVAAAVSEKGMDFSSIDKQPVNLVFLIISPKSRYLQMLSQIAALLSSEKNRELI-SAKTPEEFIEIVKRN- -> --P---LDFTTVSLTGSTMEAVVRELFDPLRNSS-VSKQAWVDLVARQAAGSVALDETVAVPHART---GAVKRLVIAGGRHVNGVPFDE-KHQSVRLVFLILTPKAEYLRVLAALASRLRDPATRRLL-TAGTSDEFARLLEDR- -> --EFIEASQIRIIPAGATKHEALEILVEALCQNP-IKEVFTRAVHEREAIQTTGLGNGVAVPHVRI---DEVSAPTVALGIAPDGLDFQALDNRPVYIIVLFATPQKTYLSLLAKVMVTLREEETFALA-ACRTVEEVTSLLGIS- -> --EYLDPRLVLPDLHATAKPAVLQELITPVADVL-GVKKALQVLLEREYLGTTGIGDGIAIPHGKL---AELDKIVLVVGRSKDGVDFEALDLKRCTIFFLVLAPEGMHLRILAHISRLLKDEAFRRDFLSTPDKESLWKLLART- -> --TYLKPEAIMLRPAAADKWQLIEALCRQLANSC-VTNQAVKTVLQREKSASTGMEGGVAVPHSAV---DGLPGLMVGMAVMPDGLEFDAIDGSVTTVIVMILVPKLGHLRLLAEVARRVSDLGFQHMF-AASSTGQIVDLWL--- -> --TILSTKTVKIGLKSLDKQGIIDELIAILHDAG-IVQAAKTAVMERENRLSTGMKFGIAIPHGKT---QTVDRLVACVGISRMPVPFDSLDGEPARIFIMTLSPPGPHLQFLAEVSQLFKDETRRERVVEAGSPAELLELITG-- -> --DYLKEENIKIDLGARNKKEVIK----GLLK-S-SSKKILQGIMKREELESTGFGNGIAVPHARI---DGIPSILILVGVSREGVEFDSLDGKPVNLVFLILAPKKLYIYILAKLIKILEKKKNIELI-STDTPQSFIEKLRSI- -> --NILSEKLVRYPLKANSKREVISELLGILVAEG-VPAQALSDILEREKKMTTGIQNGVAIPHAKT---RAVEKLTACIGIKPEGLDFQSLDGKPSQIFILTLSPYSVHVQFMAEISMVIKSEAIRNTMIKATSKGEILSVFGL-- -> ----MNEEDIIINLKARNKKNAISVMLNCLVNTK-IKRLILKVIMQREDMGSTAIGGNIALPHARL---DCVKDIVSCIAISREGIDFDSLDEEPVHIIVLLLSNQGLHLKTLAYLAKMLRDKSFVRKLEAAKEKSEVISLIARQ- -> --LHIAPEQILLDLKAGTREEVLYELAAAAQSRC-ARELVAEQLLERELQESTGHGNGVAIPHTTL---DQLGETVLLFGRNLRGVNFYAADKRPVQLFVAILVPQATYLRTLARVSRLLQQPALRRLM-QAATVEEVQEVFALA- -> -----MDEKKVIFLSSLKKIDALEEMVKALRERG-L-EGVFEDLKKREELGSTGIGRSIALPHSQG---EGIEKPLIALGVSRKGVDYDSGDGLPVHLLFLVLSPMGRHLELLAAAARLAKTLSGRPYL-ESGDPERFFEVLRQE- -> --MLIKSENIFLDVKGKTKYDIIRNMINSSTIEE--KEYAYEKVKEREELQPTSVGNGIGIAHAKI---EKIKELDILVGVLKKGVDYDAYDDKPVNIIFVILSPVREYLSVLSKISRFCRKENMINII-QENNREYIIDLFSQL- -> --NYI-KGKFKSSIKAKEKRQAIKELFETTDQ----PPPVLNKVYARERLFPTGIGHGVAIPRYIG---EEVREITLVLGLSRVDMEFGALDHKPVKIIWLLLSPDEKYTEILIRLIRLANTEEFRQVP-NLTSYEDLIELIKEI- -> ---------MILHLQAQKRMEAIRELASRLEGSD-IVKRFLSLVMQREKIETTAVGHGVAIPHAHG---DCVKSLVIGVGVSRQGIDFGAMDGEQVGIVVMIASPVQDYLKAVSRVARLLNQEDCRRIL-NAQGVAEVIEVFKQI- -> --AFLKENNIFFDLEPGEKRHVLEEFVSALKKRG-IEKVILEELLKRESLGSTGLEKGIAIPHALI---ENIDDPIVALALIKSGVNFDAVDQMPTYIILLLLGGKGFQLRLIAHICRMVKETDFVEKAKKAESSHD--------- -> --DFLKDDLFIINET-FDKKEALTFFSNVLKEKGYALKIVLEKAMARENEFSTGIGNKIAIPHIRD---NVMKTPVILFAKVK-PMDWQSLDGQKVEVIFFIALDQNSHLEVIANLSRRFMDESFIDNLLKINTFKELITLLSN-- -> --DLLSPAACDLEAH-VTKRAALEHLLRLMEHTGCIAKAFRENVLERESSVSTGC-EGLAIPHGRC---AAVLHPALAVMRVKEGCPFDALDQKPVYLFFLIAAPDSAHMQLLSRLAQLLMDKSLVQSLLAAPDYAAFCHTLDL-- -> --PLITPELVSLDANLGTKTEVITSVAGLIAAAGR-ADGLAHDTLDRESKSPTGMPGGFAIPHCRS---AAVSQVSLGFARLSPAVDFNGPDG-PADLIFMIAASEADHMKLLTKLARALVNPEFVEQLRQAPDAQTVVDLIGG-- -> --ELFTAQSIALDEALQTQEEILSRLVELQATHGNITEAYKKALYAREAEGSTYVDNGITVPHAKT---NVVTRPSLAALRLSTPVQYNAEDDGTTDLLFAIAAPESLHVDMLARMMQMLMNEDFVEKLKAAKTPKEFLECIDA-- -> --SLFSLNAIALDVAASNQDEIIDKVVELQSTHNNILEAYKKALYAREEEGSTYVDNGITVPHAKS---DVVTRPSLAALRLSSPVQYNPDDDGKTDLLFAIAAPQSLHVDMLARMMQMLMNEEFVEQLRTAKTPQAFLDAIDK-- -> --ELLCLERIDLNAN-VNKNDVINYLIELMMVNDNIINVYKQEILNSKIQNINEIIGGITIVYAKT---EVVNKPGISVIVVKNKIDYDSLDELSTRLIFMIVMPEDLYLDIIQQLSQMLMDHNFKEQLINANSPNEFLSLISM-- -> --EFLTAENIHLDTPASCKKRALEIAGKLLADLSDCPIACFDALLKREKLGCTALNNGVAMPHAKL---ANACKPIAVFLKLEQPVDYEAQDRKEVDLIYAILFPEHHYKAYLPKIAEKLSDKNIIKQIRTAETEEDIWQLFCY-- -> --DILSPHRVLVDCHISSKKRALELLSKMIAEDGVTHQDILHGFLARERLGSTVITKGIAVPHTRL---AQVERPIGAFIKLHEPIAFDNHDEHNVSMLFGLVMPEQEHISVLSCLAECFQCQTRIAQLNDTHGIEEAYRLLTL-- -> --SLSPNPLITIDLDVHSKKRTIEHVASLISTR--CINDILESLILRERLGSTAIGSGIAIPHGRL---AHLDKAIATLVLLKEPVDFDAADKMPVRIVFGLIIPEEQHLTLLRSIASIAQDPTALHILNSNKDAHVIFHWLKN-- -> --ELVKADSVKHDVDAGSRKRLFQIIAEASVDPDKAVDEIYDALVERERLGSTALGDGVAIPHCRV---G-CERISGAFYTLAEPIEYEAPDEKPVDLVFVLLVPKKAHIDALQRLAQLFSDASHLACLRNAQCNESLFAELKR-- -> --EYLSLDRICPCIHSSSKEELLLQISQHLALA-HTAQDIYATLMAREALGSTGIEDGIAIPHGRL---TALQTPLLAFTSTTAPIDFGAIDELPSDLFFVLLAPLSTHLAILASLSQLFHQPEFSQQLRYCKTAEAVMHCIQR-- -> --ELINPDNVLCNAHARSKKHCLQILSELLARS-ISNEEIFSRLIERERLGCTSLDAGIAFPHCRV---EGVTASSGALMKLSSPVDFDASDGEDVDIVFGLMVPVDNHRADINMIASSLMSQDLRAAIRAAKTSKELYQALLS-- -> --TLLTPERIAHAQEMSSRKRVFERLAELLASAL-SAEVIFDALTNREKLGSTALGNGVALPHTSI---V-IPEARGALLLLEEGLKMDAPDKKPVQVFMAILVPASDFSPCITELASILLQKPLLKQLYHYREPADILNYFNG-- -> --KDIEIDHIVSDANAPSKKSALSHLADHI-AEV-VAPVVLDHLIVQEAHQNSSMGEGVAIPTLTL---KQAREPYTVLMRLAKPIPFDSVDGKPVDLICLVISPSPLKLRRLSRIARLFKNKELLEKIRNTEDEDTIRALIHS-- -> --DLFPLQRILIDEVYQSRKRVLEVLAGLLADDGAHATHIFEILIERERLGCTAIGHGIAIPHGRD---KDILRPRGAVIRLTEGIDFGSADNQPVNLIIGLIVPDESHVAILGILAQHLADDKDREAMLNTQSAERIRGLMRE-- -> ----------MPLVLHKPTQRVLEVLAGLLADDGQESTRIYEILIERERLGCTAIGKGIAIPHGRD---ASTLRPRGAVIRLTEGIDFGAIDNQPVRLIIGLIVPAENHLAILGVLAEHLSNEGDLEAMMQTQSPERIRGLLIE-- -> --AMLEKNCTKSAVLFNSKKRILEYIAELAHQQEMSEYSILEALMTREKLGSTGIGGGIAIPHGKL---DCVTSPILIFVVSQDPIPFDAIDNQGVDIFCAILIPKQAHLTTLSGIAKLLTQKDLTKKIRHASSDQELYQLLMD-- -> --SIIEPSRVLRNVDARSKKHALDILSEMIAGA-LAQGAVFDSLISREKVGCTALPGGVAIPHGCI---DGLERIIGAFVKLAHPVDYDTPDGVPVDLMFAIVLPDTERKACLKEAGQIFGDPAFQRMLRSAKSSRTLYDMIIG-- -> --LLLSPERTLFVQALESRKRVFDTLASLLAHKL-DKVTIFDALIEREKLGTTTIGKGVALPRARF---P-ITHPCAALLVLKEGITIEAPDKQPVSVFLALLLPEQPYSDLLSDLTMRIASRSVSEELSEISEPQIAVNYFET-- -> --SVLELTTVHRFSDLVSKKKLFEKLAELL-IVL-TFLRVLGNLNAREKLGSTYIGKGVAIPHCKI---AV-EAVKAVILILDEKIKYSESNQQQADIIFALLVPEDQHLHLLSSIARLCEDNNWLDGLRKLNSEKEITNYINK-- -> --DLLSPDFIVMHPKVSSKKELFEQLLEALKPQ-SQFDAASEAVWARENVMSTAVGFGFALPHGKT---HEVSQHMGVFGVLAEPLDYDGDNKEQVQLVFLLVGPKANHIKLLSQVSKLMNKEVLRQEILRASTAQEVYGLLKE-- -> --DLLNPSCTSAQSDVSSTKTILDKLAHLLGEQ--GSDKILEELVARERLGSTAIGHGVAMPHAKL---SSITSPMLAIVTTQNGIDFDAPDDELVDIFFGLILPDGEHLQSLKCITELARQEEVRKSLRAAADQQSLVDVAIT-- -> --HILVRSRVLSSCHVNSTKASFEIGAELIAST-LXARELXDAXLSRXRLGSTALGNGIAIPHCRS---EXCTHPSAALMHLHESVDFD---GELVNLLFIWVVPQTVHLNXLDALSRIFGDIENVKKLRXTKSNEELFDIFIK-- -> --ELITPGRVACNIKVGSKRRALELLGGLIASDDLTQPEVFESLVERERLGSTGMGRGVALPHGRL---KDRPRAVGAFMKIEGGVDFDATDSAPVDLIFGLLVPENEHLQILARLATMFSDTELCASLRNCANRTQLVRHILD-- -> --NLLPINNIKIDVDLSSKRRVFDEAGLIFEES--SRQHIFEAFLEREKMGSTALGNGIAIPHGRI---DSLKKSTGAFIRSSNGIPFEAPDNNPVFLFFFLMVPSEMHLQILSELSQLFGTQTVVKKIKESRDPKVIHQIFSD-- -> --EILSPERACSNLQASSKKKAIELVSEKISLS-LKSGHMYRGLIDREKLGTTAIGEGVAIPHCRL---DNCQQITGGLFVFNTSIDFSAPDEKGVNIIFALVVPKSQHLKTLSALANFFSKPSNRYELLNAGNDQKLYHAALK-- -> --TELGLHHALCGEXLLSKKRIFERAAEVMGIADLQSXPIYRALLAREKLGSTAIGEGVAIPHCRI---NHLSEAAGCLVSLKEPIDYGSTDGSEVDIIFVLLVPEQDHLNLLAGLARVFSESETRAKVRSANSAGQLTDLFIT-- -> --PLLSPTRIALQVSLSSKKKSLQAVSELFAKDSISKDLVFDALTDREKLGTTGLGDGIAIPHCRY---ADCCEPLCAIMTTDGGVSFDASDGKNVDLLWALIVPIDDHLQALALMAEKLTKTEICQAIRQAQDPAKLYLLLTN-- -> --ELLSPARTQRGVKGTSKKAIFEEVAALVAADELDVGDLIGKLLAREKLGSTGLGGGVAIPHCRL---ANCAEPLGALVTLGEPADFDAPDDTPVDLLVVLVVPEQDHLDILASIARLFSQAPLRAALRACESNRALYDTVVG-- -> --NALPIDNILLEMSATSKKRAFENISLFF-ERI-SSSAVFKSLLAREKIGSTYIGNNLAIPHGYV---YDLKKTIAAFVRLNRPIIFYNQNRQLVNTLMFFLVPLEEHIKILTKLTSNLLDKTTNKILQTEDKKIIYNTIIKQ-- -> --DLLGPDAVAAGLRTGSKHRLFEEIARRIAPG-DVALGVLEALTEREAMGGTALGAGAALPHGRC---DALASPVGGLFRLATPIAWGADDGRPVDLVAALVVPVGRHLELLAELAEAFADPGLCARLRVAPDAGALRGELAQ-- -> --DIFTPELTICAQNIDSKKQVLSLISGLIAEA--KAQHILESLTERERLGCTAVGYGFAIPHARI---QSLTKALCVVVTLPAPINFDSEDHQMVDSIFGLLVPEEEHLEHLSEIAQRIKSSSFRHHVKNADNHSALYQALVQ-- -> --NLLTPARILCDVRGASKKKILEHIALRISEE--NPRELLCRFVHRERLGTTVLDSGIALPHCRS---KCCPAPVGLFIKLNTPIDFNTTTHTLVDLVFALVVPEQNHINLLKQLVTRLQSQKLLHDIRVTSSPEEIYRRLIA-- -> --DILHPSHIAILSDCQDGDALLNRLAGLLAGDPQLCEGIIASLRQREQLGSTGIGHGVALPHGRN---AAFDMARAAFVRLPRPIDYAAADGVPVDLVLALAVPAHQHLQLLADIAERFSNPALRQALRLAPDAATMHTLLTQ-- -> --QLLAPDRVCTGLSGTSKAEVIDALVDVLADHAAIAEAVRSAIFEREEKMSTGVGKGLGLPHAKT---PAATDTVAAFATTNEPVDFGAVDDVPVRLLLLLVGPESQHIKILGRISRLVSRDSMRERLVAADTPETVIEALREG- -> --SILKPGLIKVPLDGESKRAAIDELCDLVCTSSAVTDNFRKTVWEREGQRSTGIGEGLAIPHGKC---PGVREITMSIGIPQAPLDFDAIDGEPVRMIVLLASPAADHIQALGRISKFMSDPTVRSRAYSADCGEDLYQLLAGL- -> --ELFAPERVCLKLNAATSEEVLAELASLLGGRDP-GEIIRDGMAAREVVCSTTIGGGVAFPHARV---EGVTAVRAAFVRTAEPVPFGAADGLPVDLFVGVVGRFAQLISTLSRLLWIFRTEASREWFRQETDPARIVQGFSRV- -> --DTLKSGCFCLELAATTKDAVLEELVAILYNAGKIQDRVLAAVREREQKMSTGLSDGIAIPHAKT---DTVTEMTTVLALKHNGLDFQSFDGQPSRIFIMTISPAGPHVRYLGQIGKLLKQPAIRERLMASVTPDDIVRALTDL- -> --TLLPKESIASIPGVNSKEELLHALVDLLSNELTPDTRIRESVLLRESVMSTGVGKGIAIPHGKC---SSVDRNFASFIRLDQPVEYQSIDNVPVRYAFLLVGPMGEHIKLLSRISRLLNSRSFREKLDATTATDELCAMIQKE- -> --DLLAPDRVAVRVSVATREEAVDIAVGLLADCPSVVARLAADVEGREALMSTGVGEGLALPHART---SAVTSTVATLCTLAVPVDWDAHDGAPVDLVLLFAGPEATHVRLLAHLSRVLSAAKVRHRIAEAETPEALVAAVVEA- -> --EFLAPESVSMGIAAHDKAELMAAMLKLVAGRPQITSVVERDVQAREQAMSTGVGKGLALPHAKT---QGVSETVAALAVLAKPVPFDAVDGLPVQIVFLVLGIPSQHVKILSRVSRLMNQEAVRRRMLAAKNDDELFAALEDA- -> --DLIQEKTIRAPLEATDKQGAISELVDLLSDEGCITEIIKQAVWERELQRTTGIGEGLAIPHGRC---DELDSMVMAMGRPSTPIDFASPDKRPVELIILLVSPTSDHIQALGRISRLMVDRSFRESAYATENANDLFALFQNA- -> --ELLSPKNIGLPLRATSRDEVITELIELVAASGDISDEVLRKAKEREEILSTTVGKGLFVPRARS---RHISRFCLSFGIAGSPLDLGALDGNPIKLCVFLGVPDEEGVEYLVRIFRLFNQDSFRSALLKAKSRKDIIHVFEEE- -> --ELLHDGNVIADLDVTTKQEAITTLVHTIRESVGEEQTALTAVLEREAVMSTGVGKGLAIPHGRV---KGIQDNFVAFGKLRTPIDYGSIDQKPVSMIFLLIGPESQHIKLLSRISKLMNNDAFRDRIASCTSSAEIIAFFTEE- -> -REFFSEDAIKLDLQATNKDAVLKELVGLLKLDDKADAMLFKMLKRRETLGSTGIGQGIAIPHCRS---LVVNRLRVAFGRRLEGVDFKAIDDRPVHYFFLIVAPPNQYLPVLGKIAQFAKESDVPTRLAKLKLSTEFLELLEEK- -> -YLLLHEENIVVGLDALNHEDALKKIVDVLPGWSLQGQKILELLILRERIGTTAIGHGIALPHCFS---SEVHEPIVAFGVSSSGVPFPSLDGRPVHFIFVLILPREQKRQILQNIKWSLCDRYLQERLKGAQTASEIHRLIVSE- -> -SGFLKKENVILNIKSKTKDGALEEIVNKIDLT--KEELVLLSLKQREVLGTTGIGSSIAIPHARS---VVLNKLCLYVGLSRTGIEYDSMDGKPVYILFLIIAPPNQYLILLGKIASLSKKLVRKKGYLKVENEDQLIALIKKY- -> -LALFEKELYIPELDAGNKQEVLEEFVELLHREERVFDIVLDMLLKRENLGSTALGNGLAIPHGRT---LTTRKLVVAFGKCTQGLDFDAPDGKPVHLFFLIIAPYDQYLPTLGKIAEFFRKKRLREKVLQVSNFEEFVDVLSSE- -> -SHFLKKENVIFDLKSKTKDKALEEMVDKIKLS--KEELVLLSLKQREVLGTTGIGNGIAIPHARS---VVLDKLCLYIGISPKGIEYEALDGKNVNIIFLIIAPPNQYLILLGKIAALSKKLIKKKDYLKIDKYEDFIALIKKM- -> -MDFISRENVAPDIKARNKEELLTELVGMLHTCGKIGAPLVKSLLEREKIMTTGIGRGIAVPHAVS---PEVKDQSIILGRIPEGAEYESLDRAPVYFVFLLVGPPSIHLKTLARISRLIQHTNFVESIKKAVTAEDILKILAEE- -> -LKHTSPQLFLPNIQATDKNSALTELVKGLIDGTEINDNIMQMLQSRENLGSTAVGPGIAFPHGRT---LSVQRLTILIGRCPEGVDFVSEDGNPTHLFFVLIAPPHQYIKSLATLIDCVQDADLRNKLMAAEDYDAFCAAMKGD- -> -TESLPIVSIDLNLKGKDKVQVLESLVALAGKAQTFEGEVVAALLERESLSTTGIGNGLAVPHCKT---PQAKQLVIALGRVPQGINFFALDGHPVRLFFLLLAPQNSHLKALAKVARFAKNPSILQELMDQPDPERLLAFLKEQ- -> -LSYFHEDLFIPELRTSSKNSVLKEMAAWLESSKKVYSIIYDLLKKREELGSTVIGGGVAIPHCRS---IAVEKLTVLFAIKSKGIDFKSNDRKPVKLFFMVVAPP-NYLVFLGKLVELLTDRKIKKMLSKVKSFEEFKDLISGI- -> -SRYFSEHLFIAQLKAKNKEQAISELLDLFVKEKYIREIVLEMLHQREKLGSTGIGKGVAIPHGRT---TAASNVLIAFGKSEAGINFDAIDGKPVHLFFMVIAPPNTYLPILGALVTMLNEKSNRDKLAKVKDFTEFLPIITGE- -> -TDFLDERFFLQELNSRTKNDVLQELMRPLIESEQVQELLHETLRQRELMGSTGLGKGIAVPHCRS---TLVSRLLLLVGRSSKGIDYDAVDKKPVHLFFLIVAPPNDYLPLLGKIVEIVRDGRKRKAMLKAE---GFKALVRVF- -> -ITYFDEQLFLPDLKATSKDELFEEIVDQFVKIKYLKEILLDMLRRREQLGSTGIGKNVAIPHGRT---TSASDVMIAFGKSKQGIEYNSVDNKPVNLVFMIIAPPNIYLPILGKMVEILNKSKTRSKLMEAETYEEFIDIILKG- -> -LIYFDEQLFLPDLLAKTKDDLFEEIVDQFVKVKYLKEIVLEMLRQREKLGSTGVGKNVAIPHGRT---TSASDIMIAFAKSKNGIEYDAIDGKPVNLIFMIIAPPNMYLPLLGKMVEVLNKSKNRNKLMQAETFDEFMEILSKG- -> -VDVLDKNLIKIPLAGNDANTVIEEMVGLLSDALNLGDDILQAIKRREALGSTGLGKGVAVPHAKT---SAVQSVKLVIGVTSHPVDFNAPDNEPVSLFFLVVAPPSSHVEVLASIARTCSSAVMMKHIKNAHSADAMYSLFRE-- -> -MLTLHQECILLNLQATNKEGVLEELTQLAVQHYNNLQQLLATLLEREQIGSTGVGNGVAIPHGKM---LGLEEIIFCFGRSTGGVNFEAIDNRPVFLFAMLLSPLSDYLKALAHVSTVLKEQQNRIMLLQDPSPKDVVSLFTPP- -> -REFFSEDAVALELQGTSKDEILKELIGLLKLDEKSEGMLFKMLKRRENLGSTGIGRGIAIPHCRS---LVVNRLRVAFGRKKDGVDFKAIDDKPVNFFFLIVAPPNQYLPVLGKIAQFSKEGDVPTRLLELTSPAQFMALLEEK- -> -MDLLPRRAILTDFEPPDKIAALKKLSELLAPHTSSLDEIFRILLERENLGSTGVGRGIAIPHGRC---KNIRRPVLCFAKSTKGVDFGASDGKPVHLFFAMVAPETANIKVLAKMAEILKNPTARDALFEAHNADEIAEVLSRY- -> ---LRKYVEVSFSNFNTDKMKLIEEIAEVIIWLDNESQTIAKGIKEREALSTTGFGNGFAIPHGKI---EGLESPILAVFKLEKEVEWDSLDDEAITQLFIILVPVDTHLALLSTLSYHLMDEEVQRKINEITENEEMKRFIEM-- -> ---VKSEVIIRFDNQATSKSAFFQEAAVALGL--LHIPTIVLALEERERLSTTGFGDRMAIPHGKV---AGLDIPHVIFMRLEQPVEWEALDDQPVNECFFLMIPANVHLKLLSKLAYHLADEVYQQKIHETRDAEEMMQVIEE-- -> ---PVIHAAVEVKSDADGKDRLLKEIVQLVTACSFSFNEVYQEVMTREELSTTGFGNGFAIPHGKS---SDLEKPIVSVCKLARKMEWEALDDEKVDTVILLIIPKDLHLKLLSALSYNLMDQNMQEKIREADKEDELSDVIES-- -> ---VDYYIDPSKTFQSGKKTEIFKEILDDVSHSAFDFEEVLQEIKKREALSTTGFGNGFAIPHGKS---SQIHTPIVVLMKTDQKLEWEALDGQPVSIIFLLIVPKAIHLKLLSRLSYHLMDKKIQEAFKNAETKEDCEALLNQ-- -> ---LITPSNIIIDGDVKDKEAGLYM-IAEKEELGISAEETFKGFIEREQEMSTGFTDGFAIPHTRS---DSIQYPSVIVVRLKHELNWETMDGQQVKIVIALLVPKNMHITLLSQLSRKLMKASFREEVMNSFDTESLFGCFKE-- -> --NLLSIERVIPNLYAADKSDALRKLAA-VANSATPADLVVSAVLDGAEMPAFGPGTGISLPHAFI---PGLGDPFVIFAKLNPPVDFGSTDGSKTDLVALLLSPLRGHLQALACVARTLRDVHVRKLLRGAESRDSIYAVLCGY- -> --EILNTNQIHFDFIATSIEDIFQHVEAGLKDNKIRFRRIKKVLRLGHEDTSYTIGNGIAVLNAKT---FGVNRKVIGFLRLSKPIDFKADDGKQCDLIAVILSPQPLHLRRLSRVSRLLKDTKMVDKLREAEDADVLKILLGSP- -> --GLLLANGIIPGLAAFSRDAVLMALARHA-ELGIPAIIVNEALRTREALGSTSFGGGVAIPHARL---AGLDQCQAALARLPQPIDWQSSDREQVDVVVLLLSPESDHLKALARISRTLRDPATLPAIRAAADAAAIRAIITGD- -> --ECLDVNHIYVGIHLPGKDDVLAFLAEKAAGLAMDSGALLSGFREREDSFTTGIGLGIALPHTTS---AQCTKTTLFLLRLSRPVDFESIDDQPVDVVLALIIPTSEHLQILARTARLCKQQAFPEALRQSPDAGTLWETIRRF- -> --TILTSQCTRAALAAPSRKRALQAASELLAQTPISARLLFDELMSRERLGSTGLGDGVAIPHCRM---PCK-EIQAAFLHLAQGVDFDAIDGQSVDLLFVLVVPTTAHLEILANLARVFSNPDNRATLRGAKSDAQLFEVMAGL- -> --PYLFETGVLVLENVKDRDSVLRTAADAASITPISAETLLGLLLGREAQSPTGTPEGVAFPHAMV---PGLATSLVVLIRTGQSVEFGP--GRPCDLVFTMFGDAWEHVRLLARLARLTGRSDARDRLRAATDDASLYAMIQAE- -> --DILTEDRVRVTRHQDGVKSEVLEALSLLLG-GQAAELIHKTLTDRESLQSTGIGDGVAIPHGSL---EALVTQTAAIVLCPDGVDFHSIDGRPAKIFVGVIGPRGEHLRMLARISRLLRDGNLRDRLLEASDGTQAFDVIVEE- -> --DLLLGGPVLPALNCTSAKQVFSRLSSAMS-TGVSDRDILHAIVEREKLGSTAVGHGVVLPHARL---PGIQQPIGGFARLLTPVDFDAVDEQPCDLVFMLLASDADHLRALAKIARVMRHAGLRKDLRDAETEQDIRDIFCAS- -> --DLLPKNAILTDIKKTDKNEVLRDMTHFMAYLNHDPEILTQKILEREAEISTGIGYGIAIPHVRL---AGIDRCYMAAARSKTGIDFNAIDDQPVHMLFMLFSPVTEHTQILSSLSRIMTWEEIREKLLQVDEAQEFLDVLTEG- -> --VRLELAAVRDCQDIGNKSDILRTIARIGE-YRLDAEAIRTGLEAREALGSTGFGRAVAIPHAKL---PDIDHCIGIFLRLSEPAPFEAHDGKPVDLIFALLSPEVEHLKALAAASRFLRDDNMVAKLRGASGQDALYALLSKQ- -> --NFLCNRCIIPDLNTKSKEEALVRLAQRVAEPDVNQDSVLSVLKEREQLGSTGIGGGVAIPHGKL---PEMSRMLIVIGRSPAGIPFDAIDNCPVHIMFLLLAPSISYLKILAKVSRLLKIQKVQQRIMEAPDARSIQKVIEEI- -> --SFLTQQRTHCHLRLSSKKRALQEAATRIADPSLNSEDIYQQLSDRERLGSTAIGQGVAIPHCRM---PGCRKVTGALITLAEPVDFEAFDDEPVSTLFVLLVPPDEHLKVLALLARNFESEHYRRALTTARGDDELYARALYI- -> --DVLTPEMSLCDLHWSSKKKVFENLAQFISLDTDRAEALFQSMVARERLGSTGIGKGVAVPHCRV---NGLNRVYGCLIKLNFSVDYDSIDNQPVDLIFALIVPDDDHEKTLAYVTKVLQRANSREKLRACRNNQQLFNTLIKL- -> --GQSGVLRVLPSLKAASKKDVLAELLEPVLLGSIQASEVYQAIINRERLGATGIGQGAALPHALI---AGFANHLAVCGRSGAGVSFDAADGKPIHFFLLYLAPITTYLHCLAMLAGFLRSAHVQARLLAVRDAKAIQAILDEF- -> --DLVGASHVVLQLAAEDKWRALCELCHIASGVGVGADVLLEAVEERERSLSTGLEAGLAIPHAFL---PGLPHAALIFAVAPSGIPWGALDGEPARLIALLIAPEATHLQVLASLSGAWVEPSRRAAALAAPDAAALRAVLSGT- -> --GLLDRHSINGHVSVNSKRQALQAVADHA-LFRMDADVIFNALVDREKQGSTGVGLGVGVPHAAL---EGLTQMRGIFLRLETPIDYDSIDHVPVDLVFALFAPPSEHLRALAKVSRLLRQKSMREQLRLLDTNDALYALLADS- -> --SYVAAELTWVMDGAGSCEALLAELAERIA-VGGDAAALLAALTARERQRPTSTPEGVAFPHAIA---EGVTESHVAVVLLGEAVEFDTVRHERCDVVFVLVGPPWLHVRTLARLARICHA-GGADRLRLATDDADLYRLLIEE- -> --ELFSTDHVFLKVPVTSREQLFAFLSERA-LGLVNSQLCTKALHVREELGSTGLGNGIAIPHARV---EGLEKVVGLIATLERPINFEAVDGEPVDLVMMLLLPEGDQIKALSRIARVARNEAAVNALRRAQSVDEVTEIIEGV- -> --ALTRPDLVFPDLPATDSQGVLRDLAGRVAGLVKNGEELFQSLWEREQLGSTGIGQGVAIPHCKL---KGLARGVVAVGLVPAGVDFGAVDQQPVKVFFLVVSPAAEHLQILAAISRWIRADQHAGRLLTLHDPAAVYDLLRE-- -> --EIFRPEDVAIGVDAPTVKQVLLQAARLLASN-LPEAEIFKALVDRESLGSTAVGHGVAAPHARI---QGAGRAHAVFLRLARPIDFEAGDDRPVDLVCAIIGDYAELLRTLAGACRGLRNAETLAKLRQARNSGELYSMLIEE- -> --EKLDASNVVLNI--EGRTQIIEKIIQQLHG-AFDEEEALEKVLKREELGGTGIGFGVALPHARL---NSAEDILVGLGISKKGIDFEAMDGQPARLIFLVLAPEETYLKVMARISRLMRKEEVREELLCCDIESDVASIIEKY- -> --SLLNSNQIFLQLKSAEKEQFLENFISMLSEKTLNQSIIKDLIIKRENLCSTALDNHVAIPHAKI---PGIDKTYISLATCPEGIEFGSIDGKKTKILILILHPENRHLEILKSVSVLFTKENVINEILNFDNSQKLIEYIKHN- -> --SQPQRALIIPALQATAKREALRELAAAACYPQLDPEQIRRVLEEREELGSTAIGDEVAIPHGKI---VGLEEMVLICGRSEAGVSYGAADGRPVHLIFLLLAPFNSYLSRLAELARFLRQPQVRSRLLQATSREEIAAILAGD- -> --DCLPLENVVVNLSASSKRELIGKLTDVA-KTGADAAAILKAITTREELGSTGVGNGVAMPHAAV---AGLDASFCMFVRLPKPVEFEAVDDVPVDLVVLVLTPAGQNLNVLSCAARRLRDCNVLSAVRTARSAEEVFLVLTNE- -> --DYLKLDDVMCDLEVSSKTQALHAMADVVSGG-VPAAALLAALQKRERLGSTGIGQGVAIPHTRI---EGVETPRACLARLKKPVEFAAIDDLPVDIILMLITPDNRHLNVLAQFTRRLRFPGVLEGMRTAADARTLCAHLTDK- -> --KMIGKDSVLLDLEVKNKKQLLEDLSKYI-IISKEEREIFNILLEREKLGTTGIGKGVAVPHGKL---PKLERIHLLFAKTKKPIEYESEDGQSVDLFFLLLAPEADHLQALSEISKMARNRETRKTLREANNVEEIIKIFKSA- -> --EAMKPDDLLLGVSASSKDKLLQLLSEHAGLA-VSEETILTALRSRESLGSTGIGAGIAIPHAPV---DGLVAPFVLLARLAKPVEFEAIDEEPVDVVCLILTPPNRYLKLLSSVTRQLRSADTLGTIRQAADRERVYRAFAEV- -> --EVMQPNGVLIDVSVPSKFKLLKFVAETAALG-LVEGDVLNAVQSREDLGSTGIGAGIAIPHASV---EGINLPFVLLVRLTMPIDFDAIDEEPVDIVCLILTPSSHYLKLLSSIARQLRSVDAATTIRRAADREIIYQALITC- -> --EILTPKRCHNKISVTSKTRLLSTISNIIANKSLDADTVFCSFVERERLGVTSLGKGVAIPHCKI---AACTKITGSLITLENPIDFGASDGQPVDLIFALVAPNKQHDNTLAEIAKLLNDDDFCFMARQTFDNEDLYNVTIMT- -> --DILLPAHVVVGLRCSDRAQLISELSSIA-TVALSQGLLSGRLLERERLGSTGVGDGVAIPHARF---EELAQPFALFARLQRPIDFDAIDGKPVDLVFLLLLPAREQLPLLASVARHLRQQAIARELRAAADASTAFQVLTRA- -> --DMLAPDAVLLHLKAST----LDDALQQISAVTGLASPLILAALRERTAQGVGMGHGVALPHARL---DGLRRVAAFFARPLAPIP-SPDGGEPIRLIFILLAPQAAHLKALAQVARVLRMPESRMALEQAPDKNTAYALLVAA- -> --------MVRVGLEAVDRLGLFRALVGDLAEEFQNQQAVFDAVVHREGQRSTAVGEGFALPHATS---EHVPGLLMAAARLARPIEFEAPDKEPVDLVFLVLAPPAPFLVLLGRLARVVSRKDVASDLRSAPDEESFEAKLQEL- -> --DYVDEKHVIFIDEKLDKDALLKLFAEKFRELDAISQAIFEALYERELLSSTAVGEEVAIPHAKL---ANLDDIKMIIAISKVGQDFQAVDNLPVKLFFVVIAPAQLHLKALARISRLVKMTDFKKRALEQDSAKKVIDILVEE- -> --IFDDPKTILVIEEDFEKNQLIRKVVEYAHAINIVEEAAYNAVIKRESMGSTAIGDGVAIPHAKL---PFVVGINIIFCYLPNGVDFDAVDHNKVRYLFLILSQETLHLKALAAISKLIKNTGFINQLSGEMELIRIHSILKEC- -> --KLFKPKSCIAKLKAADKDDALREIVTQLVKSLDAEDKAIEALRDRERLASTGVGMSVAIPHVKI---PGLERAACSIAIHPEGLEWAAVDGNSVSIFFTVLRPAQAHLEMMSWIARLGRDADFRRFAERARTKTELVDLLKEM- -> --DVVSEDLILPSLQGIDASSVLKEFADAICSTGKCSQALFDRLYEREQQESTGIGNGVAIPHCKI---DNLKDVLVGIGYSESGVDFNALDGKPIHFFFVVVSPSVMHLRTLAALSRLLKSQNFLSYLRQRPKADLISRIKKEE- -> --DYMSPEQVYLDAPIRGKEEILHFVSQAFAQCGAAPRTVYDCMKEREDIMSTGIGGGVGIPHAAC---AGVTRPAVVIARLARPVDFQALDAHPVDVIIAMVVPNSLHLRLLAAISRLVKSTNFLDDVRSASSSGDLFSHIKEI- -> --PFLQQEHICTAVDATTRDELLRVAAQKINSVCADLQTLFQALWEREELGSTALGSQVAIPHCKI---EGLDQIRLFVFTSARGIDFGSPDGQPTSLFFVILSPPSEHLQVLARIARLTRSDGFVSDALAASDPVRILQCIEQY- -> --DILKKDSIIANLVGTKKEEVLHEMTDFLQSQNLIQETLFKTLTEREKLGSTGIGENVAIPHGKT---DEISQIITVFARSLGGVDFEALDQKPVHFICLVIAPSGQHLKALARISRIFKNQNLRDNILKLQDASQIYSLLLEE- -> --EYLCPACIVAELKATDKEQVLLELAAAA--AGAHLNAVHAVLLERERHGTTAVGNGYAIPHGKL---PGLDRMVLTFARSVAGVDFAAPDTVPCRFFFTVIAPAGQHLGLLGSIARLAKDATFTNRLTQAKTAEDLLDFLAGA- -> ----------MVEFNAPTREGALNALVHHLLKLKLIEEELYQKLLEREMMESTAIENNVAIPHCKL---EKLKNPVILLGISRQGVNFLSIEKKPTHVFFLVISPAALHLKVLASVAKIAKSKDLMKKIIAEKDYSRIKQLIKEE- -> --ELLAEGVILCPLEETEKWAAIEECVQALPHVASRKSAM-AAIRERAQEHSTILDNGVAIPHGIL---PDPAPLAGALGVSPVGVSYGVG-ARKAGLIFVIVGSRREYLGILAQIARLFRGLDLKNKIMQAKLPGDVLQLIRDA- -> --ELLKPEAVLLDLEAADKWQALEQICAHLRGAGLLPSSILALLSEREQSMSTYLEHGVAVPHASA---IELGQEVVGLALSRRGVPFDSVSGEPAQIIVTLITPRLLHIRTLAEVARLLSHGSVRKSLLESDSPEKVLAAIRRG- -> --ELLSEKVILTNFKAGTKLDAVGRLVDVIIASGDIPQAVLDALIARENICSTGMEHGVAIPHATV---DVLERPAAAVAVSLEGVPFQSADGKNATIIVLLIITRKHNVRTLAGIARLLNYEDTRQHLLVAKTPSAILDVIREE- -> --TLLTEENILTGLSAGDFETALTALVRALPAWRVGPNRILAQLVSRERLGTTATGGGTAFPHCFS---ADIAEPVMVFGVSPDGIPYPSLDGHPVHFVFMLILPEAESRSLLQNVRWVLCDRSVKERLRSAASARDVLAILAPH- -> --ELYPPPSMLLDLQARDKQSANEEMLEHLVSQGTLDKDALKAIKKRETQASTGIGKGLGVPHAKC---DFIDGLLGVYARSAEGLPYESVDGEPAHLLFLVLSSQELHLEIMKRVATLHRDEKSLRYLAKSDDPKRITDIFREA- -> --EILTPKDLHLGFNPGDKWNGIRILVENLVAAGRLSADVLEDVLEREHSMSTGMEDGIAIPHAAV---EGIEEVLATVGFVDAQLDFDAVDGLPTQVVVLLVIPRMLHIRTMAEVARVLGDQELLARLVACGDQDEAYTLLTSA- -> --HLISPECIILQLDKTEHEEVVLEMIGHLSEIGKIAYRYSQAVMERESQTGTGLGAGIAIPHARV---PGLKEEVAVYGRSGEGVDFESPDQGLAHHVCLLLVPESNHLKILRELAKVFSQADLREKISSAQSAKEISELLCIG- -> --KLLEEKRIISELRSSNNQEAIEELINHLCDNNFLPFETIEKLITREDKTTTGIGSGVAIPHITS---DAVESTLMIFGRSTEGLDFESIDNNPVNFVILFLIPTNKHLQTLATIARFFTKGDIRERLLKATSNTEILRVIENH- -> --ELFEAQDLLVHFDPTDKWEAIQSLVQYLVTTGKLDEAVLEAVLSRERSMSTGMENGIAIPHAAV---DELDSVLACMGVVTEGLAFESIDGQPARFVVLLVIPRLLHIRTLADVARVLSKEDVRGALLDAADQEAAHQVLVQS- -> --THFRSGSVLLAPLVTDKWNLLENMVDSLSSTWNLSNLCLESVLERERCVSTGMEAGIAVPHAAV---EGLDKMVVSMAILPGGLDFESLDGQPAQIVVMILVPKLIHLQTLTEVARRLGDASFRTDLLAAASPEAVIQLWS--- -> --KLLKIDSIFHDLECQNKIEYMKIISKIMEKKSSISKTIFNSLYSREKIGSTGIGNGIAIPHGKI---KEFQSPILLFTKLKEPISFGSIDNEPVDLLLSILISKKEYLSMLFLIAKELANENSCRKLRKAKSKYKIYSILKKM- -> --KDITLDYVLYGLKSRNKREVMRDIARFVSKQGQMDVALFDQLLDQERQASSAIGMGLAIPHIRL---NDLKTPLNMLVHLDKPVSFDSPDGEDVQAIWVTMSPRPRHLMRLAKISRMLNNPQLAKQLKQARSLDELRALLFNV- -> --QLLSPESTQCCDKTNSKKKVLEKISEMMANSIDCKQSIFESLLNREKLGTTALGDGVAIPHARV---NHCKCATAVFLLLDKPIDYDAPDGKPVDIIFAILVPENSHLEHLQKIAKLLSDSKIISQIRHAHCDEALYDILEKA- -> --DFIDEGLICCNIKPESKSILLENLSKRICQKSEINTSLLENLLKREEENSTGIGNSIAIPHCIE---EKINKTICLIAQIPDGVDFDAMDDKKVKIVFLLISPPSEHIRLLARITRIIKDRNVVTSLIDSKTNQEILNILLQE- -> --AKLADLLVFSQLSVHSKKRVFESAAEAFCDVSGLSEAVYRGLLDREKLGSTALGDGVAIPHCRI---DECNAPLGCLITLSNPIDFSSSDGQGVDIVLVLLVPSKEHLDLLAGAATLLSNEQTRLAIREAVEPVDLTEIVVKS- -> --DILTPGLIFNNIKSNQKDLCLDEIIKNICSFKSLNELTQKLVFEREKLCSTALDNYIAIPHAKI---PGLTKSYCALAISKNGIDFGSVDGQKTKIIIMLLHPEKNHLLVLKNIANLFSIKELILQIIDSKDSFDIFNIIKKY- -> --DLISQNNIYLDLEVESKKTLFKFIANKISHLIKVDNLILQKLNEREKLGTTSLGNGVAIPHTKI---DGQEGVFALLLKLKRAIRFSNDDPKNVELVFVVIAPETDHLLALSVISKFLKKKNIINRTCKAKNVGQIYNLIVQS- -> --DLINEKNLIPNLVAKDRSLAYSSMLQVLLNNKEDITSCLEGLKAREAKMTTAMGGGFALPHATI---PKLAKPCYLLARCPEGVECEAVDGKLVTLFFLILTPPQEHLQTLATVAKFFNRRGIKSKILQAAGIPEILSIIRPS- -> --DLLPTQNIRQGILCSSKKRVLEVIANIAAEHQNLEHLCFEQLCAREKLGCTSLGGGVALPHAKL---AGGEKPVAVFLQLDTAIDFSAADRRDVDLFFALLIPEDAFKIHLARLAECLTDKSLCKQLRNAQSAEEIWEIFEHI- -> --QFINENSIFIDFKSKSKKNILENISHEMSNGNTKEDLIFEKLYEREKLGTTAFGNGIAIPHARI---PDLKEPKVIIIKLLDAIHFEAIDGEKVDLIISLIVPDDLHVKLLAKIAELLENKTFRLKIREAANVKDILSVVKNF- -> --EFISLESIHVDIDIDSKKNLFKLVSNIFSKNDTDKSIVTEKLNERERLGSTGVGNGVAIPHSKI---SYIQKTKVFLFKLKSAIDFSASDKKNVDLVFVILAPKSEHLLILSSISSFLKKEGLVRKLRTFKKAEEILKFISKY- -> --SLLSPKSVLCKHSSSSKKRLLEDMAEYICKQTELDNTVFRALISREKLGSTSIGNGIAIPHCRI---PQCNKTIGMLVTLDQGIEFNAIDNQNVDIIFTLLVPEDKHLQTLACIAETLSNDVILNNIRHAQQSEELLQVLQ--- -> -MDSDVKCAAFIDVKVAQKEAALATTAELLANQWSIDKELYASFVNREAESSTGFGDGIAIPHAKV---SGLEAPVVGILTYADPVEWAAIDEQPVSLAIALIVPTQVHLRLLSKLARKLVDHDYAEGLRRSAHDAQLTKQVQQ-- -> -QELFNLNHIYFDVDCKQKEAFTFIANAFVENDVSNNKKCFKGLVKREKEGTTGFNDGIAIPHARI---KEISRPGLFVFLFKDGIEWKSIDDSKVKLAIALAIPESEHIKILSSVARKLVDQEFCQNLLSAKSKEAVYKLI-S-- -> -MKEFDLQNIFTDVTVTNKNAALQKMAELFASKNQLDKALLKGFEAREQESTTGFGSGVAIPHTKI---AGLKQPLVGMTTFTQPINWESLDEQPVTIAIALLMPIKAHLSVLAKFARKLMDEQFVADLQAARHQASLYQVVTA-- -> -NNVFTPEHILFDANSTQSEALAFIATEAKKLNIIDCESFTKGLEAREAHDSTGFIGGIAVPHCKS---KHVITPAIFVVRFAHSIEWNTMDDYPITTAISFAIPEEDNLRMLTKLSRAMMKMDIRQALQQGDAKTVTETLL-N-- -> -ANVFSKANILFDHDSQQEEAFHAIAEHVNKLGYADSDSFFAGLMNREKETTTGFKNGIAIPHSND---ASVKRPGLFVIKFDHQIEWNALDKKPVQVAIALSIPQKEHLRLLSKIARKLMDEDFTKTILENDDPDILAQAI-N-- -> -MEKLTEKDLNFDLKADQKEALHALAEQAFERGKIADEIFYQELCNREKESTTGFGNGVAIPHARH---SVVQEAGILVARCKNNLEWNSMDGEPVNVCICLIAPDDFHLKTLAKISRRMIHDDFIETLKNASEADVL-AEINK-- -> --EIIKEENICIDLKSKTKKEILKELISLVKTGEILDEKLYNDLVAREDAGSTALEHGLAIPHVRS---NHIKHFSIGLGISQEGVDFESLDNEKTKLFLFIATPTNWHLEALAKIAKIFYSKTNVNVVSNCKSKEGIINLISKL- -> --KIFTAGSVTVDLHGGNKQEIIRELMLLMVSSGRVREGVIDAIVKRELRMSTGMQDGIAIPHAKS---KAVKSLAAVLGIKKNGIDFDSIDGKPSTIFIATLSPEIPHVQFLAEISKRLRSANFRTNLINSNSDEELLANLIEG- -> --NYLSLDNIVFKIKADKKEDIIKELLENFSKNDDVIDVVLNDLYERENLSSTGMQDGIAIPHAKS---SGVKKVSMVVAIDKDGKDFASLDEKKSKVFFLVVAPEREHLDILSVISKLSFEEEKLEKLINSTDKHEVFEILESL- -> -KNLFNKDTIYLNKKFDSKSEVLEFFASELVSKGYGSGKILELFQTREKQGSTGIGDKIAMPHLGD---DVISKSTLLFAKVN-NLEWESLDNKPVDFIFGIALSKSGHIEVMQKLSTLLINEKFVSELRKVDSADAFVDLLDQF- -> -QQFFNKDLIFIDQEIKNKTEAISFISLKLKSNNFIATQTQSEFSSREEQVSTYLGDFIAMPHIRN---KNVVKNSIMFIKNSKAISWNNTPQEEVKFIFAIALNDDLHIQIIQQLSKMFMQKEFLQKLEAIKTQKEFLQLISRF- -> -QDVLRQDVMLLDLQARTKEAAIDEMITSLAEQGLISAAFKAGIMAREAQTTTGLGDGIAMPHSKN---RAVKEATVLFAKSNQGVDYESLDGQPTDLFFMIAAPEDTHLAALAELSKYLMKPGFADKLRRVTSPADVIAVFDKA- -> -ADLLSPQRIELNLPLQDKQAVLERLVKLEGYGEAILEAFRRDMMAREAQGGTAVEAGVAVPHAKS---AAVRYPSLAVVTLREGIDCGALDGVPSDIFFMIAAPAELHMAVLARLTRLLLEPEFLEQLRQAITPEEFLEIVDEF- -> -KDLLKRNLMIMELKSSNKMDVIDEIAQKFFDEGIVGEEFKEGLIKRESETSTALGEGIAMPHAKV---DTVKEPAVLFAKKAEGLDYEALDGEDSFVFFSIAVPNNLHVQTLAKLSKMILKEGFIDKLKAANSPDEVYEIIDSY- -> -TELLRENQVIFNLNADNKKDAIIEMAKV-FKPDVINEKFIEDLFARESLSHTALELGVATPHAKS---RGVSKPALVIAIKKEGIDFSEGQEDKSKLFFMIAVPENLHIDILTKLADVMLDNDKLNALLNSTSYDEVIDIIEKE- -> --GILTIDRIHINVTISSKKRLLEELAISLSSSSLNKDTVSRTLTERERLGSTGIGGGIALPHGRL---NGIDDCIAAIIRLREPLNFDSPDAQPIILAIGLLVPANKHLKILSSLATMFNDSEKRKSILSVEDPSTLLKFLT--- -> --ELLSPATINLDLQSTDRNAVLAELVNQIPQFANPRQTLLNALYEREQLHSTSIGDGVALPHARNAIVGLVDQPIIVFGRHPKGIAYDTLDHQPARLFFLLVAPTTQHLAILARFNRLLRDPQLRQALLTAATPEEVLSRIRES- -> --RAIQSGGIYYRIEGNDKATALASVVKMM-HLPEVREFLLSVLLAREEIASTGIRDGVAIPHVRNPIVLQVPEPTVSLCFLENPIDFKAMDGKPVYCLFTIISPTRAHLHLLSRLSFSLRDSQLKKAIESQATRETICSHIARV- -> --EAIKKGGIHYRIEGKDKKALLNAVINLL-NLPDVKETLLEAMLVREELGSTGFGDGIAIPHARYPVVTHIPSPVVSVCFLDKPVDYGSIDGKPVSCLFTLISPTRSHLAMLSRIAHVLKDAGVKNALVAQKNRDFILTKIEKA- -> --SLLSPRLVM-FLGKHSRDEILQDLTDLVDAAGLLEQAFFDALVRRENIMSTGIGMGVAIPHGKL---ESCSNFFIAIGIHTQGILWDAIDGALVRLVFLIGGPEAEYLKLLSTLTLSLREESRRQQLLQVNTIEEVMNVFVG-- -> --DFITPDRIL-FWGKQTRNGAILRLIDRASGLGLADDAFEHAVMQREKISPTAIGMGVAIPHARL---ASIKDFFVVLGVAKNPIEWKSADPNPVRLVFLVGGPDEQYLKIVARLMLLAKSSVYREAILKATDPKQAAEQLRA-- -> --NYINNKLIT-IEEI-LKPKLLEKLIDMVDKNELLLDDFAKKIFDREEIGTTGIGRGIAVPHARC---EKLNNIVLAIAILKKEIEFNTPDDEDVKIVLLVGAPKKEYLNLLSNISKIFRNNEFREEMLKAENKEDVFELMAS-- -> --EILSPERIM-VLEESNQKEMVEKLLTMIKGSPLIKDTIKDAIWEREKIISTGIGLELAIPHTRR---EDIKGFIASAVLVKKGVDWKAIDDKLVKFAILVCSPSKQYLKLLAQTVLLWKDDYKRKKILESNDPFQIYNILKE-- -> --QLVQKAPFT-LLQTKDRDKALKTLVDSLLDKGSVIKQFYTALLERESLISTGIGLGIAIPHARI---EDCKDFFLAIGIHKSGIEWGSIDALPVRIVFLIGGPKGDYLELLALITTFIKDFEIKEKVLNTSCHQDMMDLFS--- -> --DYLSESSVL-FLNNSDKNEVLAAMVAHAASSGLIPNSFKHAIFEREAIMSTGMGLQVAIPHAKL---PEIQEFFVIPAILSQDSNWDAIDKRPVRLVFMIGGPSTDYLKILSKITLVIKNPARRKALMAAKDAKAVLAAFAE-- -> --RLISPGRIT-RIDEDNKDDCLRSLVKCLSESESLGDSIFEAIMDRERLLSTGFGLGLAIPHAKL---NIIDDFIVGLAXHRDGVPFDSLDDQPVHILVMILGPDDEYLKVLSRVTAFLKDQ--REKILSLEDNEEIXKLTFD-- -> ----MDVNNIV-FLTKKNRNDVISELIENLYKTQKIKNIFFDNIIKREKLFSTGIGMGVAIPHTKN---GDFENFFIAIGIQKNKINWLSIDKIAVNIVFMIAGPESEYLKILSKLTSLIKNESFKNKLLKFEFKEDIFAFFDQ-- -> --QILRSDCIILDKQLQTKKDVIDYMANHLYQGNYINEKFIVDINKREKESSTNMGNLIAIPHAKS---SSVKQPVMMYLRTDKEIDNDG---QKLRSFFMIAVPEDEHLKIISKLATYLMDENLLKHLLSAETPYEILNIFNNK- -> --NLFSKNLIVLNYNAISKEDVIRKMANMLNENGYLNETFIKEIKKREEINGTGIEEHIAMPHAKG---NFIKKHGIAILRVNSDGDFNSSDQKLSKLFFMMALPENAHIKAISYLSNTFSNNLLRHELMSTNNTNRFLEILMSN- -> -NRLFRPELVRIVDRFADKNACLEYMSGMLSETGCLSDRFFAAVKGREEIMSTGIGRGIAIPHARD---LTVSCLQIAVCMTREAIAYQSIDNLPVRIIFMIAVPQQQYMRILRSLSEYLRQEENRQQILKASSEEELFQYVHK-- -> -TDVTNEKLVMIDTEFNSKEECIDALCERLAQAGKIKDDFKQAVREREDLCSTYCTMEIAIPHGIT---STVLSSSLCFLKNKQCFDWDGDGETPVRYLFLIAVSGNEHMAILSKIATLTIEDDFRAALADLKSADEFINLLNG-- -> --MLFDKKLIRVNAETKDKWDCLKKMAHLLALNDILTDEFFASVKEREEFISTGIGYGIAVPHGRS---NVAKSLAIAVFHLKNTIDFNSLDDKPVKLLFMVAVPESEYMKILSAVSKFLHIPDTINNLFSVNSVDQIYEILKG-- -> -MSVFARDLIKINYYALDKKSCLTEMSEFLFEHGVIKASFLKDILERESLMSTGIGRKIAIPHTRS---KEVTQLKIAVYLLDNELEFDSIDGELVKIIFMIAVPEEMYMKVLSVISNYFRNDEKRDKILSCNSKDDLFKLLKE-- -> --------MINIDNKSVSKNEILKIMVNMVENSDLISDIFYKEVLERENVGTTGIGMGVAIPHART---EVVKDIVVSVALLKRPVNFDSLDGEKVKIVILVGAPKKKYLELLSSLAKIFRDKKIRESILESTTTECLIEAIAE-- -> -NEFFKKDLVVTNKSFKDKKEALSFFANLLVEKKYAKETVLNKALERESQFSTGIGNGLAIPHIRD---DVMNKSVILFANI-KPVNWESLDNLPVEKVFFIAMSSNSHMDVIANLSKLFMNQEFVDKLAKVNSYDSLIKLINEY- -> -ELFF----NWTAKDFKDKTSFLKQACRVLQDKNCIKQIALTALKEREAQITTGIMSKLALPHMQS---ATVLKPFVAVFKV-NNVDWQSLDNQPVKLIFLIGVPKNLHLEFISQFSKLMLQDEFANKVPNIRSFNGLINLIDSF- -> -SALITANLITLDELGDSRFDVIKHLTQAVVNAGRATETLYAAARAREEKTDTGIPGGIAIPHCRS---EAVTEPTLAMARPAPGVDFGAKDGA-ADLIFFIAAPAEAHLKILSKMARSLMKKSFTTALREAKTRDEVVVLVEEA- -> -TDLLSASRMRLHVAVADKQDALDQLIALTRQDGLLTDAFRRAVLEREEQVSTAIQEGIAVPHGRG---ASVRRTGLAVMTLNRGVEWGAMDGQPSDLLFLIAATE-SYMEILSRLMSLLMDREFQKQLRAAATPQEFLDAVDKA- -> -TELMDLKGICVGISLKEKDGVIDILAALQQKCGNIEKILKQDIFYREEQGSTAIGAGVAIPHVRS---SAVKHAGITAVTVPAGVDFEAPDGEKSRLIFLVALPEEN---PLSKLTVLLMNEDLREQLADAANEEAFLELLRLA- -> --QIFPKETVVVNLQSTEKDELFEELVEAIHSHVPGDNEALENLREREAKMSTGIMHSIAVPHALI---SSVKETVGAIGISRDGIDYDALDKAPVHVVFMIIGASEHHIQVLKQIATVLQIPGFVDRIRKCESAGAVHELICKS- -> --VFFDNGSVVWELESETKYDAIHEVIYPIFRNLPGDDQFYQVVHHRESLQSTGFGHGVAVAHGRT---PMVADSVVALGVSRQGIDYQAMDNRPVHLLFVVATHPLNYLKVLSSLITLVRQESFRREIFACLCQEEIEEKLCHG- -> --ELFPENRIRTDIASVDKESLFVELVDLIGLTSSGDGAALGCVMEREALMSTGIRHGIAVPHGKC---DAFESMVGAIGISRSGIDYDAFDGCPVHIAFLIISPRETHLRTLKLLAEILDLPGFVDALKSASSPKEVSDALELF- -> --KVFNKDAINTDLKSKTKQDAFEELLEAIQNVQPENEEALEALTARESQMSTGIMPHVAVPHALC---PSARGAIGAIGISRSGIDYNALDGSPVHLIFMLLANPSQSLRVLKHLAQLLDTPQFAADLIRKRTVEEIQGMLNLQ- -> --SLLKPENIILELESSEKDVLFAEMVENIVTTHPSNSEALAALTERENKMNTCIKSGIAVPHASC---ASVTYPVVSIGISRGGIDYEVEGGSLVHLVIMILFEQERHLHILAECAHILQTPAFYQTALTAGSASEIIEKLRRI- -> --ELFTPARIKVRVEAEDKDEVFEELVDLLVTQYRLSDEVLDAIRRREAKMSTGIKRGIAIPHAKT---ALTKGVIGVIGISQGGIDYQSLDGEPVHILFLLVSSEGLHLAVLKKIALLVENPDFYAAVMAAADAEAVYKALNRF- -> --EIFKVDNIKINIESEDKEELFEEMVNFLIDAEKLIEEILTGLKKREAKMTTGIAPHIALPHTHI---ANIEGTMGVLGVSQAGIDYDSLDGQPVHLVMMLIGKDEGHLKVLRNVAMLMSNPDFYPSLIKCKTPAELHNTIVEF- -> --KLFSAKNIKLNLESTEKDELFEELVDLYVSNDSSSDSIIDAIREREAKLSTGIKKGIALPHARI---SGLKEPRGIIGVSKKGIEYDSLDGNPVYVVFMLLSTVSLHLKILNRLNILLLNPKFLEELFRETSREGIYNMICKY- -> --SFITPSSIKVALESSEKEESFAELLEVLVAKHPENKEAMNALITREEKMSTAVFPYVAVPHALC---SSAGDTLVAIGISRQGIEFESPEPPVVNVIFEILFEEQTHLDVLRDILQLVSNPDFVKNVLQAKTSQEVYELIESM- -> --DYITPSDINLNLESTDKEEAFAELTEMLVKKCPGNTEYMKAVTERENKCSTAVFPKVAVPHAVC---DSASKTTIVVGISHDGIEFEPLESPVVNIIFQIVFERGSHLNVLRDILYIVSKPEFYEKILTLKTQKEIFDLFTEL- -> --TIFPQDRICLDLVDTAKPELFAVLVSKLNQTLFRDMMACNALQVREARLSTAIGNGIAIPHAKI---TGINEVLGVVGISRTGITYKASDDKPVQLIFLLLSPADKHLHALKLLATALEKTTLRDDILAGSSDTALWRCLQAA- -> --HLLTPANIKADLESTEKDEVFEEMLEMVVASQPSDQDALNALMLREAQQTTGIIPGIAVPHAQC---ASVRGTAIALGVSRSGVEYDSLDGSPVNFIIMMLFAQESHLQTMKDVANLLQSPDFLKTIMEKKTPQEIFDAVCNF- -> --RILRKDNVVVDLQSRRKFDVLRELSAVFDNDDAIDKQFLADLIRREQQGSTGIGKGVAVPHAHE---DSILRQILAIGISREGIDFDSADDAPVHIVALLGTPRKQHMELLAELSRLLQQDQVRDDLVAAASAADVLAIFKSG- -> --ELLQPPFLKVGLQAKEKEDVFEEMLDLFVDRGLIDEAALQALFEREAKMSTGIAKWLALPHGKL---EEARSLMMALGVSKTGIDYDSLDGEPVYVVLMVFAEVGPHIEALAEISRLFSIPGFISEIRFAETAEAILDFIRKE- -> --QLITPDCVFCAVPAKSKKRILQVISQYAAKQLGIQQDILDALLAREKLGSTGIGQGIALPHGRL----NCNKSLALLLTSDEAIDYDAIDNAPVKVFFALLAPEQDHLKSLALIAEKLSDKTVLKSVKNAITNQELYQAIT--- -> --SILTPERTFANLESTSKKRVMEQASGILTGAEPISQHLYSKLIAREKIGPIVIGKRISKPHCWVE-----SNTFAALFKLSRGIDCSAIDEIPVRIVLVVIAPQNTHLEILAMLASKFGSPVF-------------FEAVF--- -> --NFISPDDLFIRLKANSKKQVLQEMVKLAASRASIDREVFDLLIDRERLGCTGIGKGIAIPHTRCS---LAVNPIAILATLDKAIDFEASDDEPVDIVFMLLAPDGEHLTVLALASRLLSTEGIADNLRKATTVDEAWSAIL--- -> --ETLPIDCTRADISVRSRKHALEIAAELLAKKEFLTRYIFDAFMERERLGTTNLGNGVAIPHCRLN---CSR---SSFLIFSDSINYDDSEQDNIYMLFALIVPTDLHLELLAKLSAIFSDSKNREMLKSSTTDGELNNTMI--- -> --QLLSPDAIVCNATGTSKKRILDEICEKAAQQIHLSHELLMCLIEREKTSSTGIGNGIAIPHGKLP---CGNQPTAVLLTSESGVDFDAIDNRPVDIFIALFVPENQHLSTLQDIAKMFSDKQFCKLIRQCDSSEALYELLA--- -> --TLITEDSVFSQVNCNSKKSALEKISLSAAKKLNLDQVLFNELIAREKIGSTAVGSGVAIPHIKIP---SDLPATGIFLQCQKGIDYDALDGKPVDILFAIFVPEQEYLSALASISAKLLDKTLLRQLRSATDDNILFQYLQ--- -> -EGLTRADLVLLDVVATDRADAVRQLTALLVAAGRVTEAFTAAVDAREHQMATGLPGGVGLPHARS---DVATQASLAVGITGKRVDFGSTDG-PADIILLLATPASLHLEVLAGIARSMAQPNVRESLRRAYDVEVIAELVNST- -> -QAITTAEMVVLEFAAPSRNDAVAALAATLVETSRVLDGFLSDVRSYEHQLATALPGGVGVAHARS---SHVVLPSIAVGVLGNSLDFGARDG-DAHVVLLLATPASEHLTMLAALARSLAKDSFRESLRRSHDPEVIAELINST- -> -GDLITPALVDLHLDAVDKVAAIRALACRAVEAGRAGEQLVLDLKVREEQLPTGLEGGIGVPHARS---ATVTEPTLVFGRSDAGVPFGAEDG-PAHLVFLIAVPDDCHLAILAALARRLVQSSFKDALLAALEPEAVVDLVRRE- -> -NKEKVAIVTRLQLDAADKKTAIKQIVECLNVENFVTAKFVKEVFERESILPTYIGHEIGLPHSQS---DSVSKPVVAIGRLMNPIVWNDE-N-KVKLIFLIAVPKNIHLKIIAKLSRMLMHEDFRQILLVEGDEKVRKTMLEEG- -> --NLLVLDNIVVPMKNNNKSQILNELAERFVQSGNAHQELYNHLQEREHKDPTIVEENIAVPHAKC---VCIDKAGLVVGITKEPVVWNEETQETVRLIFMIGVPENLHIEILQTLGTILNDEYLVKKLLNASDSQAVWDVFKNL- -> --KLLTAERIVLDRVPADKAALFTLCAQKMAEQKRPSQAFITLLSEREKKSTTNVGEGVAIPHAQG---DIITEPTLFLFRPDVGLRWDETDDEPVVLIFMIAVPADQHLEIITRLCRWLMDDDFRQGLQTAPDAEAVLALLQSK- -> --KLIDKGF-IKILKATTKDEALSELIDLLGQRSEVKAELKKMIFYREKLMSTGIGLGIAIPHIRV---AGIEKPVVVVGLSPSGIDYESIDNQPVRVIIMIVAGAKEYIKILSQIVSLLKNEPVRQQLFQSRSIDEVYNILIK-- -> --DLVDAGL-IKDLDSVTKSEALDEMIELICQSERIVAAFREAVLARERLMSTGIGLSVAVPHVKI---SAVSDYVVAIGRSRSGIEFDSLDSQPVRLIFMVGASDGAFVKLLARIVTLIKNGTTRLALLEADDPEGIRDALLA-- -> --SVLTPKL-VCFLECSRKKEALEKMIDCLCANSEIRNELAEGIFHREELMSTGIGMGVAVPHVRL---ASIKKPVMCAAVCRNPIDYESLDGAPVRLIFMIVAGKAQYLRLLSSISSKLKNEKLRNALISASDAETFCQILSG-- -> --RLITPDS-ILLLKEAGKTDTLGQLVSSVPEAASSLKEILEKLLAREELMSTGIGLGLGIPHIRA---AGINTPVLRIGVQPKGIDYESIDGLPVKILFMILLKEREHVALLSEIVSLMKMEHLRNQLAAISSAQQGYDLLRD-- -> --DAIEKAV-LLELKAGTKDELLKALIGAVGRSSRVKAAAREAILEREELSSTGMGYGVAMPHARV---KSVTFPVLGFARLAGGVDYGSVDSEPVRLVFLLLTPAELNVQLLGKISRICQREDNRRRLLGVEKTGDFLTFIRE-- -> --ELLNKDY-IIDIRSDNKEGALKELLDVICKNERITKTFSREIFNREKLMSTGIGYGIAIPHARH---KTVKDFVIALGRKKEGLEYESIDDKPVKLIFMIGASDKDYIRVLSRLMLRLKNPDFVKKLLKNLSMLSTRLLFLF-- -> --DVISPER-VMILESASKAGVLRELTNLLTATGIVAGELERLILEREALMSTGIGLGIAVPHARI---AGLSTSCIAFGISPEGIDYESIDGSPVRIVAMIITGTREYIELLSSLARLFKDESTRERVLSARTTKELWETLMH-- -> --TILNPEQ-IIDLQGGTKDEILHELVSLASQDSNVTQELLAAILERESEATTGIGYGIAVPHAKI---SSVLDTVVVLGRSKNPVSFNSLDEQPVSIFALIAVNNKEYIRVLAKIAQFLKQEVNRENILAATNTSDVANLVKN-- -> --QYVTKDS-VMSLDGRNKLEVMDQLITRAADL-TKLDVIFRLTWKREQMMTTGVGGMLALPHIRV---NDINHPYVIVGVCENPIDYQSQDDQPVRVIVFTVAPDEAYLQLLGSISRKLRNTSLIQELVDAGNPAQILDLVHR-- -> --EVVKKEC-CFRLNENKKTEVLIEMMECIHQKGFIEENLKKEIFYREQLMSTGVGMGIGIPHVRF---KGVEKPLIAIGIKEKGVDYDSIDNEDIKIIVMIMVGEKEHIRLLSQVIGRMKDAGDREKLIHASDSEEIYNLLTG-- -> --EYLTPER-VVVLKSVTKADALGELVDVLVATDGGVEELIKEVWKREDLMSTGIGNGLAIPHVRM---SGIRLAAMVVGVSRAGIDYESLDKKPVHIIVLIAAPEETYIRMLAKVADVLKEDTLRQAAIEADEPATIHRILTE-- -> --KYLQPES-ILILDGETKKTALEEIISYATTR-CTLAQLREAIWKREKMMTTGIGNGLALPHIRV---AGFPSPLVIVGLCQNPIDYRTLDNEPVRLIVFLAADEEAYLKILGSISVKLKDKDVMAEILEAPDKKKIFAILNK-- -> --ELFNTEN-IKIVEQSSYDETLSMLLDILKNSEKIKEKFKSAIYEREEIISTGIGLGLAIPHARR---DFISDFAVSAVIINKGIDWKSIDDKPVKMAVMVASPAKEYLNLLSRIVLMWKNTGKRKRIIAAQTSEEILDALKD-- -> --AWLQPQEILFDVDVRDRPHALEVAAEAICRARLDPAPVVRALWRREQAGTTALGDGFAIPHACI---GGISQPTTLFIRTRRAIAFHAPDGKPVSQLLAIMVPEDDHLQLLALVARLFTDHSFRAQLDGAPDAAAAAEVFRAG- -> --DLLKDQDVLIDLDVPDKDALFDVASQGLANGCISAQNILAALTRRERLGPTALGQEVAVPHASV---EGLDGIHVLYARLKQPCFFDGATGMPVMHALFLIVPMQTHLDMLAEVARLFSQPDFQKALRRAESPAGIRQAFQAY- -> --RILPQENILLDVNVTSKKRAFEQAALLFENNQIARSTVFDSLFSRERLGSTALGHGVAVPHGRI---ANLKQAVAAVMRLSTPIPFDAPDGQHVQLLVILLVPEQQHLEILAELAQMLSSAETRKQLLGSPNAEGIHQLLAHS- -> --KHLDERDILLGLKAASKREVFEAIGQHMQALHISAESVASALHRREAAGSTALGCGVAIPHARV---NELERIRLLYLRLAPALVFDSPDGEPVSDIVALMVPAQEHLDVLAHVASLFSEKAFRKALHTCEEPGQVMEVIANW- -> --ELLATEHILLDLDVSRKEQVFEAAEQLFGGRHLSRNQVLYALTAREALGSTGLGAGVAVPHARI---RGLAQAVLAYLRPRTPLPFDAPDAAPVSDIIVILIPEDQHLKLLAEVAEMFQDRRFRERLSLCGDADAARRIFTNW- -> --QLITPNNISLDIEVSSREELFIFIAQQFEKNHISANSVIACLEEREALGSTALGNGIAIPHGRV---KFLEQAHIGFVRLKESINFHATDKQPVKALVIMLVPEQAHLDILAKIAQTISNNKNKNILLTEPSADNIYQLLTAW- -> --ELLNTQDILLGVEATNKPGLFELVGQHMEQTYLPRSCVTTSLLRREQAGSTGIGEGVAVPHARL---SELDSIHVLYLRPKEFIAFNTPDRKPVSDIIVLLVPAPLHLDLLAEIAHMFSDNKFREELDRCKNEQEIKNLFDCR- -> --HVFSEDIIDISKSELTRDEAIDTLLSKLNEHHYISETVKDAILKREAESTTAIGMNVAIPHAKS---NAVKQPVVAVMSNRKGIQWESLDGSLPQLVFLIAVPNDTHLRLLQRLSKSLMHDDTRDRLVHAQDKSEIYNILKGI- -> --TVFHKSLIELTNSEMKRDDVIDRLITELKNQNYVEAQVKSSVLKRESESTTAIGMNVAIPHAKS---DAVKQPVVAVLQNKNGIEWESLDGSLPKIVFLIVVPNDTHLKLLQRLSKTLMDDETREKLITAEDKETIYDILKAI- -> --HLVHPETTMIHEAPMTRDKAIDYMVENLEKQGYVTTQLKEALYAREAESTTALGMKIAMPHAKT---SGVQQPVVSVLKNNAGVTWKSLDGTVPEVIFMITVPEDTHLKTLQLLSRHLMDDAKREALLNSTSEAELYQHVEDM- -> --QMIHKNTTMIKTQPMTRDEAIEHMVSNLDKHGYVKATLTRDIFAREAESTTALGMNIAMPHAKS---AGIKEPVVSVLKNNAGVTWESLDGTVPQIVFLITVPEDMHLKTLQNLSRHLMDDAKREALLQSETENVLYQHMIEI- -> --EILHPEAVKAFGKLTSKKRLFLDLGEVAGACGLEVNSAVNALQDRESLGPTGVGHGVALPHARI---EGLDRVVGAFFRLDTPLDFDAVDRQPVDLIFALFAPAVDHLKALALVSRTMRDPDTCTKLRSNADATTLHAILTAG- -> --DLLEPGAVALRASAPGKRQALSMVADVAGRVGVDPEAALDGLIEREAAGSTGVGEGVAIPHARL---DGLDRVRAVVVRLDAPVAFDALDDKPVDLLVALFAPRAQHLRALARVARMMRQPEVRASVRQARSADAIHVLLTDE- -> --NIFLPSDVFVDAPSQTKAKTLHLAATKAS--AVDAASLLGVLEKRELLGSTGIGKGIAVPHAAL---PELGPPRGFIFQLSRPLDFDAIDEAPIDLIFLLVFGESEYLKVLATIARKAHDTMVLSAMRRAENPADL---YAAF- -> --NDLSINTILPVLKANNQKQALHIMTGYAAR-RMDQRKLLELISAERDSVSPGIGDGVAIHHLVL---QNIREPYILFARAPQPIDYNAVDHKPVDLISLIISPEAYNLQRLALVSRMLRDRVLCECLRGADSADAMSALLHEF- -> --ALLCEGCVLARLQVADSRGLMARLAEPLSRSGFAAPLIAERLIERERVGTTALGGGTAIPHARL---PGLRARTTVFATLARPLDMAALDGEPVDAVFGLISPEADHLKALAAISRFFRDKDLLRRLRGADSNDALLALLCHA- -> --DILTPERVSVEAEVRSKPEAVRRLAGLLAH-IFTADDVERVLAERERIQSTGIGSGVAMPHGRI---GSLDRFIGAVLICPSPIPFDAIDGAPVSIHFAIVGPPVEHLKWLARVSKLLRDESFRARLLAARTGRNAFELIAAE- -> --TLLPAIAGGTDTGVGDKASILAHLAALFARVALDQDLVLKRVVEREELGSTGFGRQVAIPHARL---PGLVRPVAAIIRLDSPVDFGSADGMPVDIVFGLLSPDATHLHALAAISRMMRDERMHAALVSASGPDVIYSLLSDV- -> --SL-DFDLVLPSLIAVNQKQLLRSLAQEIS--GIGERILNDRLVEKEKESPSAMGEGLSILHLHI---SGLKQPFSMFARLKNGIPMSAPDNKDVDLVCVLLTPEAAYLRTMARISRLLRDAQICVRLRSTQDEKAIRAILEAP- -> --GLLYPDTVLTDLRASNAKQVFKVLAEYTAQ-SLCVTDVEEQLLEQEAQSPSGIGEGVAIVQMSL---PELERPFVMYARMPNRIDIQAIDNEPVDLLVFLASPEPLHLRRLSQISRMLRDRDFCHCLRSAETEDAVRAIWSTA- -> --KILKPDAVRVIGAASSKKRLFQEIAEVGHLAGLNPQPTVEALLDRESLGPTGVGHGVALPHARL---DGLSEVCGVFVTLEKPLDFAAVDRQPVDIAFALFAPEVEHLKALALVSRTLREQNFCTKLRANNDPATLFTILTEN- -> --TNLTSESVFFDPKIESKDAALLFISECAAREGLDSTIIADALIERERLGPTGFGGGTAIPHCRS---DKITRPCGIFLSLAKAIDYDAVDDLPVDLIFCLISPAGAHLRALAEISRMFRNDNNLARLRGAANKDALYAMLNVA- -> --AFPPPGRILCGLRVAGKAALLEDFAHPAS--GRESAPIRMVPEKRERLGSAGIRAGIVLPHARR---EDLERLFGLLAHLRDPIEFEAIDEPPVDLVALLPLPADDSANGLACIVRRLRDPAVPSAQLAARDAPGLHVAPSRD- -> --DLLSEDSVLIDVRSSNKRSLLQDLAANAAARGLKSEDVAHNLLKREELGSTGLGGGIAVPHARL---DALERPYGVLAKLKQPIEFDAIDGQAVDIVFVLLLPSNKQLGPLALVARTLRSADTVGKMRKSKTQAELFAAVTVS- -> --NILTSDRTKAQIHENSKKRVIEKLASIVAS-DIDADDLFHHLICREKLGTTGIGGGIAIPHCRF---ATNGKTYGACMTLERPVEFNSIDDKPVDIVFAIIVPEKSHLETLACLAEFLQQPAYVNKLRSATNDIELFNAATIS- -> --DCVAPEHVELNVDVRSKPRLLETLARKAATAGVDERAVLLALESREQLGSTGIGAGIALPHASL---VALQRPFALILRLRQPIEFDSIDGAAVDIVCLVLTPAAPHLTLLSRVARLLRAPDALAKIRAAATAKQIHDVLRGI- -> --DILTSSDVIVIDDAVSKKRLLQEMSRKLAEDGIDERTMFDIVAERENLGSTGFGGGTALPHGRI---PGLRHVKGVFAKLNKGIDFAACDNRPVDLVFMLVSPEADHLSALAQISKIIKDEERCEKIREAATGNDIYRLLTSD- -> --DVLSKKTVVVELKGHDKNAIMAELTDCLADEKVLSDAFLKAIKEREALESTAIGGGIAIPHAKH---ESVKRIFCAMGIIKDGVEFNALDGKPVTAVLMVASHPREYIQVVARAARLLKSEVMMQKIYAASSSPEIMKVIADF- -> --DGMSVERI-VDLKATSKDEAIAELIDLAVTASAVDEQLLGRVLEREALTSTAVDRGVAIPHARS---EQVKGVVVSLGIHRSGLDFGSPNGDPVHLVFLVLSAPPAYLSILGRTARIFRSEQMLQSVLGATGAEQIVKIIAAH- -> --DYIAEDTIALELRGEDKKSIIEKMAQILTDAKKINDVFIEGIQKREEIESTAIGNGIAIPHTRG---DFCDRIAVCLGRINKGVNFNALDGKPVYIIFMIAAPTKEYLQLIAKVARFLRAENNRKRILMAGNKEEIIQVIKDF- -> --NFLKKERVIMNLKNDLKEKILEELIEYIPVGKISNAKIFDEVMKRESLESTGIGNGIAIPHAKF---NTLGGFYIVVGISKKGVDFAAIDGKPVHIIFLVVSDTILYIRILARIARLLHNKSFNEKLLKQTTENDVINFIKKY- -> --DLILPQHVA-WLETRSKSEALSQLLQRLSQSRAVKAALRNAVLAREVLMSTGIGYGVAVPHAKI---PTVESFVVAIGISPDGIDYTAIDDAPVRLVVMIAGPDEGYLTLLSTLMRFIKSE--KGKILSSTTPEDVARLGRRY- -> --DVLAKEHIIINLYGMNKFEVLEKMVKVTKSSAKVVVDLLEKVITREKIKSTGIGGGIGIPHAQT---LGVTDFIACLGISQDGIDFNALDEKPVHLVFLIATKENIYLELLSSIARLFVDETFKQKIIKSKSPDEIMQLISEK- -> --EMLDESRII-DLKASTKDEALRELVNVLATSPDVTDDLMEAILERERVISTGVGIEVALPHVKI---ASVKDFVIAIGRSTRGIDFESLDEKPVYIIVMIGANDGEFLKVLAQLVLKLKNKNFRKGVMFAKDAARIKQMFVRP- -> --ELIERAPLV-ELTAKTKEEALRQLAEAFRGEPKVADRFIEAIFAREKVISTGIGIGVAVPHVKI---PEVSDFVLAFGRHREGLDFDSLDDQPVHLLAMIGASEGEFLKMLARLVRTFRARDVRRKLMQAENAEAFRAVLREN- -> --EYIARERIA-FIEAENKQDALAKLIALSEDDRLVINQFQNAVLDREYIVTTGIGQNVAIPHIKS---RWVRDFFISIGVFRNGVEWQSLDEKPVHLAFLIAGPEERYLRILAKLTLIIRDKEKRKAIIGASSPDEVYRLLENS- -> --RLLSPERIV-WLSSCDRGEVLSELARLHTSFDTTIEEVRRALVEREQLNSTGIGQGLALPHARI---PKVQDFSVILGLHKGGIDFNSFDGEPVHLFLLIIGPTDRYIQILARASRFLRAK--AADILAAATADEIYAMTLDF- -> --RLISPDRIT-WLDQDNKIDCLRGLVQCLSKSEELGDSIFDAIMEREQLLSTGFGLGLAIPHAKL---NIIDDFIVGLAIHREGVPFDSLDDQPVHILVMILGPDDEYLKVLSRVTAFLKDQ--RESILSLEDNEELYKLTFDY- -> --DCLSIDRII-DLECDRKAEVMECLIDVTSTASVVHEDFRQAILRREEILSTGIGLGLAVPHAKI---GTVSSLVMSLGRHLKGIDFDSLDGNPVNFVVMIGANKQGYLNILAEISGFFKDVTFRDRIMRARGPEEIMALFS--- -> --SFIEQQQILVGLKVNSKKHLIEALCAEAAKAHIESRDLCAAVMKRERLGSTGVGNGVAIPHAAI---NSVDEPIAVMAILDSPVAFDAADGRDVDIACLVIGPEQAQLQMLSSVSQVLRKATNCSKLRAAQTAAEALMAIQNI- -> --EFCFENNLMLGVPAKDKRSVVQIIASHLALRTMPFNVIFDGLMDREALGSTGFGDGFALPHALI---SDLSTPARVLVTLREPIDFDAADDEAVDIFVAVIWPQDGFLQHLAKLCRLFRSKKLLVALRSARSETEASILISAH- -> --DTLGAGDVLLIDALSVKEELLGLIGAHFAGVTLERDDIAEALAKRESLGTTGLGDGIAVPHAPI---AGLDTACLTFVRLGSPLAFDAVDGAGVDLVCAILFPDPAGLKLLACVARTLRRPDVAKELRKATTADEIITALAIE- -> --NLLNSNSYLMIDNPTSKKMVFXTMCIKAXETFIDXNQVLNDLXKREKIGTTTIGNGIXIPHVQN---NFVTKPVSIVTILSKGLDFDAIDKVPVDIXVFLILPESENXQILAQVSRXLRNSDIINKLRGSKSEDSAFAIISQF- -> --EFLKSKHVIFDLHVNNKKHLFQELSFKSSLIKIDDKELFNGIINREKLGNTYIGNGAAIPSAML---ENLSNTFILFSVLTKPIDYNLDDQKKVDIICLVVSPKSKHLYFLSNFSRILKHDEITKRIRGCDNPDSLKAVIMNF- -> --EFIYKNSIFIDVTADSQKNVFKILGNIFSKKNNLSSLIIDKLNERERLGSTSVGNGIAIPHTKV---NGIKETQVIFLKLRNGVDFSASDGKKIDLVFSIIAPESDHLLILSSISSFIRKKQKVDRLRGSTTIDEILFLFSKI- -> --NFIVRDAIIPSLAAPVKETVIREMVGALHAAGHFRDEIVRAVLRREDLGTTGIGRHIAIPHSRH---PAADRLIGTLALSRDGLPFDSLDGEPVYVFILLVSPQGDHLRALEAVVRTMRNDDFVRQLRACQTREEIWALLESA- -> --DIVVPDAVRARIRATTRDEAITELVAALVEAGAIAPEIIKAVIKREGQATTGIGKGIALPHAKL---KGIKKPIATIGGAPDGIDFSSLDSKPVYSVILLLSSPDEHLQAMETIFHHVQRDLFRKFLRQAQTNEAIVDLIHEA- -> --DLFSIEQIVLDSSATTKDEAFQELATIAYKAGCIDDKLTKALWAREHETSTGLEDGFAIPHARI---KYIKKPAVIFVRYQTGLSWPTFDNSAVQVAIALIIPTDIHLEVLSNVAKKLLNPDLRQTLKKENDKTKILALLQAE- -> --DKLSKKQIILDLDVKSKEEAFTQVSIIAKKLGFIKKILEKLFLERELEISTGLEEGFSIPHAKG---PQILKSGIFFVKYKNNLEWETFDNKGVKFSIFLLISESNHLKVLSQISMKLVDKEYRQKLSTTNNVDEIIKLLEHT- -> --ALTSNDLIILDQDYSSKREVFQAVADRLKQKGTISSNFIDSLYAREKDGPTGMDKGVAIPHAKS---SQIKEPVFSIVRTKKPIDWESIQPNKVSLIFLLAIPKDFQVKLLAKLSRAMLDDQFISTVMKASSTGQVMAELGRV- -> --HATSENLIFLDCSFTTKEEIFDFVAKQFEKENKVSQEFKKALFERESIGITGFENGLAIPHGKS---STVKEASFAVVRLQKSLEYASLDPSKVDTLFILAIPETTHLTLLADLAGRLGDINYLNQVKSAHNAKEMIKVLKQK- -> --SLTHPSLINLQTTFTSRDEAIRALAEQLDQQGKLHQQYLDAVFAREEQGPTALGEGLAVPHGKT---DAVKEASFAVATLKQD-KWKGLDEDDVNLIFLIAIPNSTHMHLLTELTTTLVDDDVREAVLNATTTDELLALFNKP- -> --TIVKREMIFDNIKSRDKREAIRIISHLCSRHNAAYLRLIDAFRKRELLDSTGFGGGIAMPHARI---RGLCDPVFAVVRFAWPVEWEAIDGEPVDLAVVAITPANKHLPTLAMLARKLMNDEFVYNLKHCTDKNQLYDYMLR-- -> --DLLKPENIHFDVNGHSKKSALKAISKLCGHYSTIKSALYKNFVGREKIESTGFGGGIAIPHAKI---DNLTNPFIAIVRFSKPVDWDSIDGKSVQVAIALVMPTNTHLEVLSHFSRKLADDEFLNRLLTEPDAVALYNYIIE-- -> --ILVKKEKIFDNIVSGTKKEAIRTISRLCAKQTMLDTQLEEAFWKREEWDSTGCGEGIAIPHAII---KEIDEVQLFIVRFRYPIEWESFDDKKVDIAFAIIAPEEKYLVFLSRLARKLVDEKFIANFRNCRSTEAVYQYVKN-- -> --DITEEHLMDL-NLKSTKTEAFKEMLAFKGIDQFINETVLEALEAREAESTTGVGQQLAIPHAKS---AAIDQVKVLYGYSEKGIDWDSMDGQPANMVFMILVPENTHLKILQMLSRKLMNDDFRTAVMNAKTKEELYQLFKE-- -> --EYLRPEHIVLDLEARDSAEVIQTLVRRIPELEAVDAAVAEALLAREAAHTTALDNGVAVPHATV---AGLDRPLLVVGVSRDGVRYGPAGLEPVQVFFLLLSPPALHIKLLARIARLVRRPGLVERLGGAASPEAVFRELERV- -> ----YLTPLYLKDVSAVSRLDVIRELSALAAQEGLDSATIERKAWERELIAATGIGHSVAIPHARL---KDLKEPIVAVGTSEAGIPFDAPDGLPAHIVFLLITPQEAQLELSADIAHTFREPRCQEQILRASTYTELVAALKT-- -> ----LIQPHI---IPSLAAGTRRDALAEMVRLVGFDQGPLLTALQEREAIGSSAIDPGLAVPHARV---AGSGELEVCFARSAAGIPWGAPDRQSVHLIFLMVASRDNYLETLANLCRFLRDSSNRTLLMKASAEE-LVSFLTT-- -> --TYITLEAVRLDLNLSSLKRLFEEAGLALESAYIPHDEAFTALNERERLGSTALGFGCAVPHARL---TGLEEPAVVLLRTLEPLKVPSPDKTGAQLFIVILAPEDDHLELLRETAELFSDAEARETLLKASTPVEVCEFLTH-- -> --SLLKPDNVLLGISPSSKKRIFEQASQTLSLLYLDKKEIFDGLFARERLGSTYLDHGIALPHCRL---PNIKEPCCLFVKLHGELESDRPGEPSVSAFFFLIAPESEHLALLASAAEVFSDDALREKLLTASSADAFCGALRS-- -> --TLLSTDRIIFTDEVSSMKKAFEQLSRLLCRNSVCADEAFDVLISREKLGSTALGNGIAIPHACM---P-IPEPVAALLVTGEGIKMDSPDKKPVHTLLALLIPSKSYRPLLKAMAANINQKDLSRILLEQQHPGVALEYISS-- -> --ELLPPANVLVDVEVNSVKKLFELMGVFFENRYLSKDVVYQALFARERLGSTMLASGWAMPHAVI---TSISEVLCGLVLLRNSIVFDQRGWRASVFLFVLIPPSDRVSCVYNEWRLLSEQKDVVETVEGMDNPSALYQYLFH-- -> -MEINKPEFVFINLKQKNRDDILKELATRAVKLNLATDELYQAFLAREKESSTALPDLFGIPHART---ATVKQPALLFAKLHQAVEWDEEKK-QVQYLFVILVPQNTHLEIISNVAKLIMDKNANQKLISSNNPDEISKLIVSY- -> -MKIFTIENIFLNQKLDSKQQVFDFVAQVAVEKGIVNKQLVVDLWSREEQITTGIEQEFAIPHCQS---NVVSKPTLFFISLQTGIDWQNFDGTLAKYLFVILLPKTTQVETLSKIATLVLDSKISSILK-SNDKNAIFEAITSQ- -> -SDLIHPELICLDLNSTTKHAVFNEMAEYLFRAGKIHHAFVQEVLKREATGNTGFEGGVALPHAKC---ASVLSPAVMIGISREGIDYGAEDDKPTHLLLMIASPEEAHIEILAQLSARLVDDDSVSRILACRSEQEVIDYFCRP- -> -SQFLSSELVKINLQSKDKKSAIKELSGLFETKQIIKNQYIADVLKREEEVSTELDNGVAIPHAKS---AAVIKPAVAIGISRNGIDFSGE-GRLSYVIFLIAIPQDTHISILSNLTSHLLETDCIQKIKGAKTEQEVVDIFSKE- -> -NKIFSKDLIQLNIKSSTKNECIEELASLLYKQGKITKKYLQDVHKREEEFSTELENGAAIPHAKS---IHVKSPAVAIGISKKGIAFGSDETKKTHLIFLIAMPENTHIHTLSTITSKLLDENYVTKMINSKSIDDLIYLLENN- -> -HALFSEKLVKLSLTGLTKDQIINEMVEVLWKDGRLSEQFTKDVYAREAEITTDLEIGAAMPHAKS---KAVCQPSVAIGISQKGVIFGES-KEKSYVFFMVAMPEKEHIEVLGKVTGVLLEKENITALKNARTEEDVLQLFCQE- -> -LDFLKRELIFISDEIKSKEDAINFLVDKVGEKGYTDNGFLQGILDRENIGDTSWENGVAIPHFIG---DVVKTSFVSLYIKGDGIDWSDD-NPPVNLIFLICMSKNEHIKSIAFIAKLFENDDFKNILKTVNNPDEIYAYVENV- -> --NLIDKDHIQTQISISSKKALFAHMSEHICQLHLADEELIYALAQRERLGSTCIGEGIAIPHCRL---PHNGKCILSLYTLAEPLSYND-DNETVDIVALLLVPEDTHIELLSQLAHLLFKPELRSELKSAKSNTDAFRAL---- -> --EMFTRDNVLVDVPADSQEDALARIAAMATDRGYAAEGVLAGLQAREAQMTTALMDGIAIPHAKH---PAITEAALLVVRFSEPVAWPT-DKALVSVAVTMLVPETTHLKLLAKVSRALMDEDLRATLTSG-TADEIYTPLSAK- -> --DILNTDQVEFDLSATNRNDALHQLAQLAVAKGIATEAVYQKYLNREKESSTGMEQGIAIPHAQD---ASIERSAMLVVRLTKPVDWPSFDNQPIDTMISFLIPEGAHLHYLSNTAKLLTHQSFIKDLKAAKTPVDVVQLFRNP- -> --DVIRNDLIFTDVQVSSQEECFEQLADIAVRSGLATKAVVSGFEAREKESTTGMEHGIAIPHTEL---AEIAKPALIIMKLADGVEWNSLDDSETRLVLAMLIPKHGHLAILSEISKLLVHESFINELMQAKTKNEIEQLFKEK- -> --TLLDKGNIYFEKGIQTKDELFRFIAEKMQDKGIVSERLVEAFRKREEQSSTGMENGFAIPHAQS---ETIKKAAMLAVKLEEPIDWQTFDKKPVTFVIAFLIPPEAHLHYLSDTAQKLVDQRVVTALNTATDADQVYALLH--- -> --DVLQKENISLAVQGSNKDEVLQNIAAIAKEKGIISAATYHGFLKREQQGSTGMEQGIAIPHTEN---NAVIRPALMVVTLARSVDWDSLDGQPTTHVLAMFIPTSNHLNVLSDVAKLLVHDDFITELKTATDTTTIYNLFQNK- -> --NLVDSKRVFLNKSFNNKESALEFIAQQSVETNVSDNSVFEGLKARESESSTGMENGIAIPHVSD---KSISNASLIVIKMDNKIEWPSLDGKPTNFLISILVPEEAHLNILANLSRKLMDKEFTNQLISSNSKEEIVNLLSGV- -> --ELFNQNTSFFKQEFKTKTQIIDFLASKLKEEKIISTVFLNAIKTRENQESTAIGNNVAIPHALN---SVVLKPTICFMSLKTPIKWNSNDNQLVDLIFMIATNDNDHMDAIAGLSSKLLDDNVLEQLKQIDNFDQLIELFSDD- -> --DLFNQNTSFFKQEFKTKTQIIDFLVSKLLEQKIISTVVLNAIKTREKLESTAIGDGIAIPHALN---EAVLKPTVCFMSLKNPIKWNNNDNQLVDLVFLIVTNDDDHITAIAGLSSKFLDSNVLNKLREIENFDELVEIFNDK- -> --NLFHRKNICLDEASQSKTAVLLKISQLIHQNNLSIESLFDAFWKRETLGSTAIGHGIIIPHIRS---QAAEETQACFLKLKTPIDFGAEDKQPIDLVIGLVVPQTQHLALLNGICQEFGKPSLRNACRAANDEEELFRLLVK-- -> --QVIHPGCVCVDSSSQSKTAVLLKISQVLSQVYLDAQELFDAYWKRESLGSTAIGQGITIPHIRS---TTIEAPKACVIRLLNPIDFGAEDKQPVDLVIGLIVPQNQHLQLLDAIIKQFNQTSFRELCRQTTCSENLYKLINS-- -> --ELLREENVILDREAKTKEEVIRILTKHILTENGVTTEIVKAVAQREKLAFTGIGKRTALVHAVT---AGVKETKAVFLRTVSPVDWAKGKDYPERIALLLLIPEGEDVEKVKQLVLKLGKKENARRLLEVSTKQEVLKILNGE- -> --ELFSATDVILDAAPGTKAALLDRLAAEAAVRGRSAPEILEALLAREKIGSTALGRGVALPHTEL---AGLAAPVVLFARLQRAIDFDARDDEPVDLVFLALWPAKGLLAAMAEICGGLRDPQSLRRLRGAKTPEDAAQIILQ-- -> --TILGDEDLLLDQPIDSKAAVLAAAAEHLGRSGVPSEVILKALSDREALGSTAIKHGVAVPHAGL---DNLPRPAAVFFRLAHPIEFDAPDDNPVDLVFVTVWPSSGLLSALGHLCRNLREPSVRQALRTASTPQEIKSALSR-- -> --ELFSAADVILDAAPADKPALLDRLAAEAATRGRPAPEILGALLAREKIGSTALGKGVAFPHTEL---ADLAEPVVLFARLQRAVDFDARDDEPVDLVFLALWPAKGLLTAMSEICGALRDPQSVRRLRGAQTPEDAARLLLQ-- -> --DLCPVQQIVLDAPLTDRNALLTYCANLAAPAGVRASVLLQQLQDRERIGPTSLGRGVAIPHARI---AGLAAPYLLFVRTLQAIDCDAPDGKAVQDFFVLLMPAQLHLQVLADLVSALHDRYFRQALHAATSAPAINLLLSS-- -> --LDIIPEEIVINLPGGDRASALHHLATVLSRERVPTQTISSALLGRERMGSTAIGGGVAVPHALL---TDIAEPAKCLAILKHPIWFDAPDSEPVSVLLALLWPTNSYLPSLAGLMRRLRDPKLREALAAAQSVEEAALALSV-- -> --SVSFEIDFTIDRTSRSRKAALGSLAQRISCRDISPHDISNCLLAREKLGSTAIGSGVAAPHTIF---KQSCTPLVQVTQLKYAIDFDASDATPVDVLLSVVGNRRWLHLALPRFAKLAEAPELAARLRAAKSASAVEDILAS-- -> --SVLDPSLFVPDLRTRRKESVLGEMIARALAGVRLPELLRETLVLRERAGSTAVGKGVAVPHARS---LSVSEPHLVVARSRRGLAWTPGDPQPVTLVLLALSPAEGHLDFVARVVGATRLQRNRQKLLEAESFDAVAAVLRE-- -> --EWLTPGAVRFGLHADDVSTALAAIADHLEPRALHRRELLQRLLDRERMESTALDNQTALPHCKM---AGLPAPVVCIDRSEDGVPFRPGSDERTHLFFTIVSPEATHLKVLAAVARFLRDAQNVRAVLAATSPSEVLEYIQR-- -> --KLVRPELMNFDVVPGDKMKILGQLTFPMIQSKFLTKYFLDRLIERENMMTTGLGNGVAVPHPRQPIPNLFPESAIAIGICKEGTDFDADDGKTVYAFLTVCSSDVHHLRILARIAKFASDKSATKKLIKARIPEEIIDILKES- -> --RLIKKDLIVMDIKPGTKNEVLEQLARPVLRNGTVYSGFLEKLMHRERMATTAIGKGVAIPHMRNPRENPVSGPALVIGICKAGTDFEALDKKKTYLFFFICTDSVIHLRVMGKLAGLMRDEITVSRLIESNGRDVVLKIILEK- -> --ELITPDCVRVQKSVVDKRHVLEDLTTLAIRSGRLTTALLRSIEERESMFSTAMDEGIAFPHPRRPLEGL-QEPLLAILIVEQGVIFGAPCGGKTYVFVLFCAPDSAHVRMLARLARIFYQKKLISKLRRMQNPELIIQELINV- -> --RLIHRDLITLEIKPGIKEEVLSQLVEPFVKNGIIPAEFFRRLVSREHMASTAIGKGVAIPHIRHPEENPAGGPLLGIGVCREGTDFDSFDGQKTYLFFLLYTDSLVHLRVMGKLAALLHDEKTVSRLITAQKEEDIIKIILHS- -> --RLIRRERILTGLPAGSKEEMLDALIAPLSLSR--EKLFLKKLMQREDMSSTAIGQSIAIPHLRRPEENIITGPEVILGICPEGCDFDSIDSKPTYLFFLIITDSVVHLRIISRISQIAGDRKLIRKLVNATDGERALGLILDS- -> --RLLTEDRILLDLQATTVEGIIEELTPPMLFSNLVFNDLREKCLAREQIVSTAVGNGLAVPHPRDPITTLRAPGCVIIGRSVKGVDFGAADKKKVHLFFFQCSQSELHLHLMGRVATLLRDEAFVKICRNAKTPEDIIASVMEH- -> --RLIDPGSIIMNMRSRDRDGVLRELADLAQARELVKDTLFSKLVQREQMLSTGIARGIAIPHIRRPGETDIQEPAIVFGRSPEGIDFASLDGTKTHFFFLLLSDSTVHIRIMSRLAAMLRRDDAREQLRRAEQPQDILRFFVEY- -> --RLTDESCINMDMKSRKPDGILYELAEIAQESGIAVENLLIQLKKREQMLSTAIGKGVAIPPPRNPSDELFRKTGLIIGRSAKGLDFDAPDGKKVHLFFMTCATDVLHLNLLSKIARLLDADGFIKRMIRVKSKKDIMKLLLES- -> --RLTDESLIVTGIRPGSAEQILNALAAPLAEQGIIRHKFVDSLLQREQMMSTGIGGGAAIPHIRHPEELPAARPALVIGTCPEGIDWKAIDDRPVKLFLLPVSADVSHLRLLSLIRKVLLDEELSSRLIQAAAPHELISLLLKY- -> --RLVDTGSIIMNLKPGTRREVLAQLIRPLEAMEKITAAYLDILLAREEMMTTAIGP-IAFPHARNPRENEGAEPQVIVGICREGTQFGSLDGSPTYLFMLPFTDSIIHLRLMAKMAVLFKEEKNVRRVLEAKSGEHVVGVLISL- -> --RLMYPGKVLLDMTPADKPGIFRQLVQPLVQDRIIGEPFIIRLQERENMVSTAVGRGIALPHPRHPGDVHATRSSVVFGRCPQGVDFDAPDGRPVTLFFLICATGVVHLRIMSRLAWMLRDVAFVEQLGSVVSEADVLTAIMRK- -> --RLIDEKSIITDLKGQTTKEVIHELAEKAYINEFVANIFIKQLLEREQLTSTSIGQGIALPHLRKPNGNIVTEPKIVIGVSKEGIDFDSLDGEKTTLFLLLLSDSVVHLKLLSKITRIFGIDNAISQIKQLRKPEEFVKFFNKI- -> --EILRPELMSLGLRPGPKPVILRQLVAPLVEAGFARSRLLAGLMEREEMMTTGIGNGVAVPHLRRPVPGMFSTPAVAVGTCPQGTDFAAIDGQPVHTFFLICATRDIHLELMARVSWLSRQGI-AEELKDARSAQEAATIILQA- -> --RLLPVELVGLDIRPGAKKQVLEQLLDVLAGGGLPVRVFLQKLLDREDMVSTAIFPGIALPHFRKPEECPLPEPRIVLGICRQGTDFDSLDGRPTHVFFLICAGNVVHLKIIAELALLFRRGSLVEELLAAPDPASALQVLFR-- -> --SLFSTDAIVADLAADNIDGAFDELLAVLGKSKKLGKQARAAFTLKLEQGATGVGHSVAVPHVKI---PGARSTVVALGRSERGIDFRAGDGTLVNLCFLVITAEGEHLDFLRWIASLARDPDFPRFARGCQSSAALYDLLEEM- -> --GLLDHRIGIDELSTDDVASTFSAIVDALVSGGAIDDTLRDALIARESSGSTAFQYGFALPHVFS---DLVDRIWVAAARHPGGLDMAAADGEKTTIIICIVGPEDAYLSLLRTIAGIVRDGHWRRFMHQALTASDIFETLLEA- -> --DFLSADAVILDLDAADRDQVLGALADALVQRDPELDDIYNGLVEREAQGSTGQ-QGVGIPHIKL---SGISKVSMVVGIHKEGLDYDALDGEPVHVFFSVIRPEEDHLDVLRWIAGIAGHQDFVSFARQASETGQVIDLLTEL- -> --ETLAPERCQLGLQASSRKKALQVLANIFSQSSLDSFEILQALTEREQVGTTAIGNGIALPHGRL---SNCEKPIAILATLDTPVDFFASDKENIDVMFALLIPKFRDLAGIEQVKTIFDNKTFCAQIRNAHNNEALFDIIEQ-- -> --DLMAAVRTVV-SPAADRNAVLHTAAELLSCRQAGSAELYANLCEREALGSTAIGHGIAIPHGRC---PNLTEPRGALLRLNTPVAFGRD-E-PVDLIFAMAVPAHQHLMLLSELAERFSDAAFRQQLRAAPNADALMALLTD-- -> --DLMAAVSTRV-LAAADRDSALRAAAGMLACREAAEDALFHSLRERESVGSTAIGHGIAIPHGRS---STLQRPRGVLLRLQRPVDFGG-SE-PVDLVFAMAVPEHQHLMLLSELAEIFSDAHVRDALRAAADGDALKRILDH-- -> --RYLRPESVRLELNTQLTESVFGEIVELLSATGQVCRKLLTDLLNREKKAGMALEGGVAIPHVRT---MQARSFVIALARSTPGLPFGAPDGDVSRIFVGLVAPPRLYLRIYRTLAPLLMDPDWKNELLAARDVHEVLRLCEGV- -> --RFLQPELIKLELDATNKEKIIEELAVLLDKSGKVRKRLTRDLILREKKVSTGLGHGIAIPHVRT---IQVSEFVIGFARSGPGVNFDSIDSQQTHLFFPMAAPPSLYLRVFKSLAEVLRYESFRQMLLEAKDEYEAMRAFREI- -> --QVLKEETVNLNITQGMKENVIRQIVELVEHSGLVGKKLLLDFVNREKRCTTAIGSGIAIPHIRT---MQVRGFVFAIGISKDGVYFASMDGAPTHIFFILASPPTDYLQIYRRISELVQNQNIFFELTTAGTPGELIRIVKDF- -> --RFLSEDLIDLNFQVDNKEHILAALVKLIGNSGRTGTKLLTDFINRERKATTGIGNGIAIPHIRS---MQAKEFILGFARNADGYDFDSLDKQPTHMFFIMAAPPNLYLRVFKALAESLQYESFREELMQAEKPFDIIRAFRSV- -> --KYLKESSILLDYQLDVREVIFKQISTCLETVGKINTKLYNEFLEREKKDSCCIGDHIALPHLRT---LQCKELLISVITSKQGIKFNAFDDEPVKIFFSFVAPRNLYKTLYKNISRIFQDPYTIDTLLSFEQPGELIRYLKKE- -> --PIVTSQIVSLDVALDDSTQIVRALTGLLADAGRVDDVFVEAVLAREALGPTVLPGGIALPHARS---VVVTAPSVAVARLPEPAAFRADTD-PVRLVLLIAGLGAGYLQVLSKIATACVKYSFVDELLRVRTAEDMADLVGQ-- -> --ELLNPKSIFINIDVNDHNDALEMIAKKLYEANFIETRFLNALNYRENLMSTALNDGIAIPHGIS---STVIQPTISLAILKNGIDWKAEDNKKVNLIFTIVLSKEIQLDSIQVIADYSLDDNFHSEIMNAKTQEQAYEILVK-- -> --NFLNKNSIFVHSNFDKKDDVLHFLSHQLNEQNFVSKKIYEAFLYREELMNTAIGGGIAICQALS---STVKKDTLCILTMNNVNDWKADDEKNVNLVFALVLSKNLQIDTLQMISILALDNTLDNKIMKAKNADEIYEVMSK-- -> --KMLDAETINLHSDSINKYDAIKEMANMLYKSKRINTKFIEDVFKREKLESTNMDMGVAVPHSNS---IFVDKTSIAIVRFKKEIDWEDGG-EPVRCIFLFAVSKGIHLDIIAKIAEILIDDDFIDFLNKTDNSKELINKIND-- -> ---FVLKAHIRFQFDAQDKTDFFKKMVKDISVFHEDFERLLELFYLREETMSTGIGNGIAIPHVMY---EKCESQEIFVYRLAKPIDFAALDKKPVELIFVMVGASIINLQILAKLALMMKHPEFLDKLLSAESEDALFEVLIH-- -> ---LTSKNLILLDAVFEDRLEAINVLTDKLEQSGKLTQMFLDAVLKREEEGPTALGEYLAVPHGKS---EAVTEPVFACALIKGELMWQGLDGEPVNMIFLLAIPPSTHMELLTTLTSSLVDDDFREQLLQSRTTDDVITLFGGE- -> --DYLRSRNVILDFKADNKYEAIAEMSKKAKDLKIVRRWLYQVVVAREELVSTAIGKGVALLHPRHHHPTKIKKPSVIFGRSAQGIEFDAPDNKPVNLFFMLLLHDIQHLFSISYISKFLMNEENLEILRTATTNEEIIHALTR-- -> --SFINSDFILRDLNAKHRFEVLATMSQFAKENSVCTSWLFDMLSKRERLLSTGIGSGVAFLHPRSVHTDKINFSAVLLGISREGLDFRSLDRAPVNLFFLLLLKTQQHLFALSYLSQLFREDHLKEKILQAPDNKTILELLKL-- -> ---MFQEAFIVLDADYKTQAEFFCASSAILKQREYVKPSFCKAVMEREALYPTGLAIQFAIPHTDA---FHVEKPFVFVTRLKNNIPFMHMGPVQAKVIFMLGIKNEKQVGLLSDIMKCFNDGDFVRTILSIQDTHAMADYLKKQ- -> ---LASPDAVWLGLESDSAHALLSDMSQRLLDAGYVRPGYSESLWRREERYPTGLP-GVAIPHTEP----LVRRGVVAIASLARPVAFEEMGTVPVSVVFLLGLDREGHVDLLQRLIKAIQKKGIVEEIRSADDPEDVAARVNVL- -> ---KIEEDLVLLNIKAKDKVEVISKLANLLRKEGCVKDSYLNAVIKREGIFPTGLPQSIAIPHTDA---EHCLKTSVAVATLEEPVKFGLMGTVDAKAVFLLAVDNEKQVMFLSKLFHIFDDSNSLVKILNAKKPKEIVDELLRA- -> ---MLKPSLVLDDLAGDSREEILRTMAEYLVKEGRCRRTFVEAILARERLYPSGLPPKIAIPHTDT---IHVHRSALLFVRLRTPVEFASMGTFPVQLVSMFALQNDLVGNVLQTLITLYQRRQMLEDLLRSKDAREMYQILVSA- -> ---FFKNDLVFHDVDWVDTADFFHKISENLVRGGYVAPTFYGAITERELNYPTGLQIGAAIPHADP---VHIKEPFIAVIRPTHSIAFAPMGKIQAKIIFVLGVMRGLQVKVLQRLMGMLSDEAVIHQLLQASNEDEILRIIKNS- -> ---LLDKELIVLQSNAQHYSDVFKELGQTMIDKGYANANYIEGLLEREANFPTGIQAGIALPHTDA---SFVKKSKIGLLVLENPVQFGMMGKVQVNIVFLLGCSENQHLLALQKVIELIQDADFVEKILSLESKNEAYELLSSN- -> ---MIPRDFIFHQVNVQNRNEFFEHFSNLLEKKGFVKTGFASALKIREYDYPTGLP-GVAIPHTDG----FVQKDAIIVATFEHPILFHEMGTVEVRVAFLLAVRDKKHLEVLQKLILAVQNTAFIEEMLAADNQIELANIVEKE- -> ---TVLPGAAIVGLEAEDAPTALRALSARLLGIGAVTDSFEAAVLQREEMHPTGLP-PAAIPHTDP----HVITPGFAIAVPKEPVVFGEIGTIWAELIVMLVLADHSQLAALQNLVARLQEPQAVRDMLAATDDADLERRARDW- -> ---LFQKELIFLNEHFEDQADLFQKISERLYSQSYVDSGFLLSLQTREKEYPTGLHFDVAIPHTDP---VHIKRPFIVAVRPDPPLDFQAMGHVDAALIFILGLQRGNQVLLLQKLMDLFLDEQKMKQLLRIADQEEWLKEIQYF- -> ---AEQTGFIGTTLEAKTKEEAISALAGLFLENGFVKDSYPGAVLAREQIFPTGLPFGVAIPHTDS---VHVIRPGIAIGVLKEPIEFGMMGAVQVKLLFMLAIKDNMQIQLLQDLIGLFSVAPLMNQLIVCTESERIVELVQSY- -> ---LLRPEHILLNLDASSAREAIDQTVAALVRTGHAEPAFAEDVWQREQVFPTGLPLATALPHADP---EHVRQTAVAISTLKAPVRFGQMGGLDVHILFLLAIKEEKQVELIQEVVGLLQSPGLLEQLMSAQSPERALQVLHRA- -> ---MIQKDCIFLNLKVADRHELFEQVGEKLKHIGYVKDTYVDALNEREAEFPTGLMLPISLPHVDS---VNVNRAFIAVVKNDKPIHMLQMGDMQCEYFFFLGITDSHQVILLQKFMQLLRDKSFVDRLICINNVDDMFEFMQEN- -> ---TFSNELILTGIKAASDLEAIETAAKHLFEKGLVKESFISAIQEREKVFATGLPFGVAVPHTDV---EHVVEQTICIGILEDPVPFKVMGEVDVKIMFMLALKEHSQLAMLQAVIGMVQKPDILEKLATEKDTGAIYDLVMEE- -> ---MIHQDIIFPEREVKNQGEFFHFVSRDLYEKGYVHPSFEKAITTREKKYPTGLQITIAIPHTDC---EHIIQAFLCVNRIISPITFMQMGKVFPEYVLVLGITQKEQVTLLSEIMELFSQETFVQKLRCATTTSDIYSAFIEG- -> ---IFREDLIWLDETFEDKDQFFDKIGKRLYEKGKVKESFADGLKSREAVYPTGLKYEIAIPHTDV---EHVREASISFVRFKETVLFSHMGQVNAKFAFVLGVKESQQVEVLSTLVLLISNEAEMAKLEVLNSPAQICALLNEF- -> ---MLHSSCVQLDVEAQDWQDAIRKACRPLMGKGFVTEGYDEDVIARELQWATGLPVGVAIPHSLT---PHVITAQIAACRLSQPVKFAQSGKVDVSIIFVLALKDKEQLSLLQKLMTTISNEETLASLMGTSTPLE-------N- -> ---LFRPENVKLNVKCCAAEDVIRQLGWALTENGDVVDGYAAACEEREQLYPTGLQTGVALPHADS---HYVKRSAIAVATLLEPVTFRKMGDVSVRAVFMLAPQKEEQLLFLEGLVAFFQQGDLLQKLFSRSSAHQAAQFLQKY- -> ---LLDDDLIFTEFEAKNKEELIYKLSKIIEEKGYVTRYYANDVVEREKKYPTALPMSVAIPHAES---SNVKIPSIVIAKLKNPISFIEMGEVDVNIVFLLAVKGKTQLKLLPKLISIFSNKEEMRKIEQANHSKQIFQLIKDA- -> ---TVMPQIMGYQITGTERDDVLTEMADFLASMGMVKPTYAKAVIDRENIYPTGICYPVAIPHCER---DGVLKTAILVGQTRNGITFQRIDNVDAKVIFMLAVDTQGQLEVISKLMDVIQDEKVVEEIVHAKTCEMIKEIVTNA- -> ---MLHDELIFMKYPAKEREVLLKELTGILKDRGYVKDSYSEALLTRERKYPTGLNVPLAMPHAEA----HVNKPAILVARLTEPVQFKEMGDVMAKFVFMLAVRDEGHLAMLSKFMSIFSQENQLKELYAIEDKQALREELEKI- -> ---LLNTKFTSINIEATDRDHVLTAMADQLDESGITKPGFLEALLAREKKYPTGLP-GVAIPHTDP----YVTRDALAVTTLRTPVLFGQMGEVPVSVVILMALSNDDHLSMLQNIVKSIQDGDLMKTIRNAAEPEEIVSLVRAM- -> ---IIDLDLIELNYKAENKEEIIGRLSELLQKKGKVKATFKEAVLEREKVFPTGLKITFALPHTDP---EHVNETGIAVAVLENTVKFSSMDILDVNTIVVMAVKDSKQVTVLQNLISMMQDKKITEEIQSSKDKTDILKIFKKN- -> ---LLFEELIELTLEAEDFEDAIKKIGEDAYRKGYVKEGFADAVIKREKLYPTALPLKVAIPHPME---RTVKKSAIIITKLKTPVDFTLMGTVPVNIIFTLAVNGKHQLTILQKLVGMFSEKESMERIKASTTPKEIMNSLIEL- -> ---LICPKLILCDVDAKDFQDALRQMAGHLKKEGYVEEGYLDMLLERERKFPTGLCFAVALPHTEP---DHVIKPCIAVAKLRRPVEFHEMVTVDVRFIFNLVLQKEQQLELLQKIISIFSDKEAMEQLEKEQEPEKIAEILEHT- -> ---YTNQEMILTGAKAESAEEIIRMLCGAAMKNQCIEPLFITALLEREKEYPTGLP-PIAIPHIHD-----CLKSFFSMAVTDTPVAFGCMGIIETRLVFLFGITDSYQTAVLRKFSNIFQEDEIMSGLLENDKPETLMQKMKEL- -> ---LLNRDLVHCQVAAADKNELLKKMSTAMHEQGYVKEGYIEGVLAREAASPTGLQYGCAIPHSEM---SYVNKPVISVATLSNAVTFNRMDVVDVRLVFMLAVDELKQVNTLQTLMLLLQDNEKVAELVQATNSDEILNVFDTL- -> ---LFSEDLIFIGQELRDRAELFKWFNGCMIEQGFVNESYYESILKREQQFPTGIQVGVAIPHADP---DNLNKPFIAVVRPKRGIEFEPMGNIQAELIFMLGVLKGDQVIALQKLMNLLTNNEAVQQLLEVRTCKEMMEIIRVN- -> ---IFNESLILLDVEGDSAEKILETVAQNLANQKLVKESFISAIIQREKEFATGLPVSVAIPHTDV---HHVIAKSISVAVLREPVDFGVMGTTPVQIIFMLSMDEHSQLSLLQNLMQIFQDGDVLKWLVNQKDKSEIKKLLERK- -> ---ELNDNLVFHNLKASDNIEVLQLMGDAMIQEGYGEEGFTEAVLKREKDYPTGLDIGVAIPHTDA---EHVKKEGLSIAVLNPPIEFDAMGRIPVKIVIMFTVAGDKHIDRLLQVLDMIKDEEILQGLLDAKNKKEIRTVIQKR- -> ---MIENKIIKLKVELKNSKEVLSSLADCLIEEKIVKQSFNKAILERENSYPTGLQYGIALPHTDS---EHVIKSQIAIMTLEKPVKFVEMAEIDVKTIFMLALKDNQHIKILQKVMELLQDKEAMTKIESFDDSKELIEILEKH- -> ---MIYRDLIYLDPTYTSQHDLFESLFQQLYEKGFVQASFLQAIEEREGKYPTALPFPIAIPHTDP---EHIIKPFVAVIRLRDKLLWKQMVVIAVKAVFLLGFHHEYHIRLLQKLMDLFSGTDFPDQLLKAENVEECYRLACAE- -> ---METSEFTLIGQSFQSKQEIINALFELMFKGGYVKTSYLAAVLEREDKMPTGLQYGIAIPHSDP---EHVNCSAIAIALLDQPVLFKNMADVPVQLVLMLAIAEGSVTSVLARLAEAFLNPAIMNHLSAMKTPQQLSGALS--- -> ---VLDENNILLDCSAESSEQAIRLAADCLYRNGYIGTQYVEDVLEREKSYPTGLPVITALPHAKS----DVLRTGVSAVRLLSPVEFGNMAKLPAELIFMLANAGDSHLEDLQELMECFSRVGLLRDLKVAETPAEFARIFAAW- -> ---VVDERLIFFRHRFKTYEEILEKIGSKAIELGFAKSNYVQGLKEREKEFATGVPVAVAIPHTDS---SYVNDNKVAIMTLDNSVEFNQMGKLKVKLVILLCFKDNNHMTALQNIIERIQDEEFVKSLLNSNNEQELLSIAEQN- -> ---FFQEDLVLPEITVNNSNEAIKQTGEVLHKAGFVSEEYVESVLKRESSFPTGLQLALAIPHATP---ENVAKNGIAVGRLTTPVYFQSMEEVAAEYIFMLALKDERHLEVLKQLFASLQKPSVIAALKGAKTKAEIMSVVEHN- -> ---MIETKLLYVQQQEDSVETIFKTICKKAQQLGYTKASYFNALQTRELSYPTGLACGIAIPHTDF---NHVKQPFISVMTLRKPVFFHAMDGVAVQIVFVLGLTTTAQLASLKAVMAICRSETRVEQLLHATDASELFAILTKE- -> ---QFVPELVKTDLEAVNQKEAITSLVTLLRKEGCVQDDYAGLVLEREQQYPTGLQAAIAMPHAFD---ERIKDSHVAIGILKDAVSFHNMESLNVHIIFLLAVGQHEQLEMLKILMGLFQEETMLQKMLATHSAQAICDMLNGY- -> ---TFDKQLIFNDLKIRDKNEILQYMATKMYEKGYVKGTYAQAVIEREKVYPTGLQFGVAIPHSDS---IHVNQAVIAVCIVEEPIVFHVMGEVLVKFIFMLAIDDKKHIEMLSKLSIIFQDEQKMQEIVKLKQ-DAIYEKLNCY- -> ---ALSRETCYVGVSGESSEEVLRTLSERLFQLGLVTEEYESNVILREQKYPTGLPRKVAIPHTDA----YVKETRICVAVLKHPVEFQVMGKVAVELVIMLAIKEKAQLGVLKELINVVQNGAMIEQLIGAGAGDEVYDILMSY- -> ---AFDRELVKLDEYYESQEELFNKIAAWLHDKELVHENYSEALKKRELEFPTGLHYDVAIPHADP---IHVKKPFIAFVRPANEIVFNEMAEVKPKIILFLGLMKEEQLSVLQKLMKLFSSEEFMTGCLQSVEDEKVFELLESA- -> ---ILKKELIRLAVEVADSEEALRIVAQGFVDSGYAKDTYPEAIVDRERVFATGLPFDIAIPHCDS---EHVIKPGVGIATLKDPVAFHMMGILHPKVLFMLALTEHGQLEMLQKLIGVIQDAELLEKIAACNDADALYGLMAPV- -> ---KFDETVIRVGIESVDCYDALDQLANTLCNAGYVKRSYVEAIIAREKIFPTGLPYGVAIPHADI---CHVNSSMIAIGILKDPVEFKNMGTVSTKIIFMLAMNNENQVKLLSAFMGNLQDQELLKNLAEAKNVHSVIKLIDGK- -> ---YFDSNLVFTDFEADNYEEVLSKLSNILLKKGIVKEEYPEKIVEREHNYPTGLEINVAVPHSDH---IYVNEGKVAVAILKKPVMFNKMDEIPVSIVFMLVVAEKAHLELLQKVFGAIQSQELLKQMLVIKDHQELTNLIKNN- -> ---MLEDKVIVFQKSLDSSEEALDYVSHLLLQSGAVKESYPNAIQEREKAFPTGLMYGVAIPHTDI---EHVNYSQMAIVSLKNPVVFQQMGDVEVNIIFMLALKEHQQVDLLSQLIELFQNKVLLKTLLALGNERSALGLLKAQ- -> ---TFDKRLIFRNIEIGGRDEILQYIAGKMYALGYVKESYVQAVIEREKVFPTGLPFGVAIPHSDA---VHVNKAVIAVCILKNPVMFHVMGEVLVKFIFMLAIDDAKHIEMLNKLSVIFQDRSIMNEIAGLEH-DTVYQRLTYY- -> ---LFIDDFCSASLKADSALDALTQIATLGYENNLVAQSWLAAVTQREQDFPTGLP-PVAIPHTDS----HVKQDGIGYFRLTQPVEFGEMGKIKVSVIIPLLITNKDQTSLLMSVIALVQDFEFMNQLILLDSKTQVANFLNEK- -> ---IISEESVFTDLQASNKEEALRVLADSLLEQGFIHDSFYESLINREVNAPTGLQMGIAIPHTDP---KHVKQDSLAVAVLDKPVVFQDMVSIEVKVIFLLGLSKTKHLNILKQIIELIKEEGSLEEISNMPQSDLYSYLSETL- -> ---TLDKNLFLTHLDAEDNLDALGKIADNLYNYNYVEKNYRQAVLEREEDYPTGLPPIVAIPHAAY---KLVKKTTISVATLSHPVKFHDMGILDVDVIIMMAIGQHGQVEMLQKIVSVIQDDSLRNKIFNAHNSTELYQLFNEL- -> ---LLDKKFIELDVEQSSRDSLLEYMGGKLLAENIVKETYPQAIVEREKEFPTGILISIAIPHTTG----HVNEPKIAVSVLKNPVEFCMMGKVNASVIIMIAINNDLQIDFLQRLVTLIENHELLLNIKNAASIDEVYGLLGFL- -> ---MTEIKVLALKQELNNAQDVLAYMGQQLEAMGAVRPSFIPAIQEREETFATGLQYGVAMPHTDS---DHVKKSTIAFMTLDQPVIFKQMGEVPVSLVAMLALADHSHLEMLQALMMLFQDQDLVKEAMAYSDSPEVLKLVHKI- -> ---LLDNLVVILDENYESDVDLFRKVIDSDKVRPFVKDSYFDAIVAREEEYPTGITIDFAIPHTDP---QHLVEPFVAVVRPKESVQFNPMGKAEAKLIVMLGIQKGQQIEMLQKLMAFFMEESAIDSIFKTNEEEQIRTKMHKV- -> ---ATFRELILRNVEAKNAEDAIRQVGQRFFDAGFVKDTYIDAVLAREVTYPTGLQIGVAMPHTDP---QHVYRPGVCIAQLAHPVTFAHMGLVEAEMLFMMAIQDDEQVELLQKVLGVFQQPEVVAEFRAAKTDDELFAAAQKY- -> ---LLHEELVLLNYQADNAETLLKELATILQQQGYVKDSYIQAILAREKEFPTGLNVKLAMPHAAP---KHVYKEAILVAKLAQPVMFKEMGDVEASLIFMLAVQDKNHLDALSKLMSIFSQKEKLLEVYNTVDKKRLIEKLNAV- -> ---YLDKDLIFKNLDVKDYKDAINTLASELYKKGLVKQDYVKEVLSREEIYPTGLYINVAIPHCDY---QFVNKKSIAVGILKNPIKFKKMDDVEVSIIIMLAIDEDNHIAYLTKVFNLVQNQELLKELYLSVSEEKILELLNKN- -> ---AIYEDLVVCGVDAADAEDAIRQVGRFLFRKGFVKDTYVDAVAAREKEFPTGLQLAVAMPHTAG----HVNTPAVCVAKLAHPVQFAHMGEVQAELLFMMAIQNDAQLETLQKVMKVFTDEAAVAEFKAAGDRESLYQAAKRH- -> ---MNNSEIQILKLDVSTDKEALKYMGDFLVFQGVTVKAFPEKVIEREATLPTGLPIGVAVPHTDS----YVKKRQLLISPLKTPVVFRQMGEVNVSFVFMPAIPDGEHLTLLRQLFTCFEDNQFTEALINWDGKKSLKRLIQRN- -> ---FFDRKITFFELEVDNQEDALKKLADNLYTANLVTSSFHAGILEREKDYPTGLGYGVAIPHTNA---DKVIIPQIAFASLKSPVKFRMMGEVDVSVIFMLALNKEDQLAMLQKLMEVIENQALLTEFARCKNQDEFEKLLERI- -> ---MDNSEIQILNLDVSTDKEALKYMGDFLVFQDIAEKDFPEKIIERETELPTGLPIGAAVPHTDS----YVNKRSLLVSPLKQPVVFRQMGEVSVSFVFMPAIPEGDHLTLIRELFTCFEDDQFTEALANWDGRKALKKLIQRR- -> ----MLNDVIVIDGEAKNWKDAINLTFNELYKKGYVKPSFYEACIEREIKFPTGLNIPVAIPHTDA---IHVNKQAICVLRLKEPVSFYSIEKVDAQFIFNMALKREDQLTLLKAVINIVQDKTFLEKAKKLNLNEVKNLFYKKW- -> ---MNLNDILMMDLTVDTKEQALSAMSSMLINTGYVTPNYMEAILKREQSFPTGLPYGVAVPHADS---KHVIESQVVFAALRRPVVFQQMGDIDVSFIFMLAFRDTEHLQHVQKLFLCLQDTTFMQQLNQIKKKSHLLQLINNI- -> ---PLEVKNIYVKRNFSSADDFFKVITSKLEKEGMIKEGYYNAITNREKTYPTGLDIKVAIPHTDC----FSNKTQLIVTTLEKPVKFKRMDEVSVSVIILILFDNNKQLKLLSEIMKIVKNQELLAEILKAKTPEEVYQLLNQ-- -> ---TIRKDMVFLNQDIASSDELFEFIGEKAQEHGLVKDSYVQALKDREAQFPTGLQVGVAIPHADA---EHLNEEFIALVTLDSPVEFHSMETVAADIVFALGLTKEDQLETLQTIVQIIQDDNKISNLLEAKDVDEALNALK--- -> ------MHILVHDLEVKTYQDAILTSGEYLLEKNYITPEYITACIDREKDYPTGLLIGIAIPHGNS---QFVKSDSISLVRSSKGVIFGQMAKVTCQLIFNLALATDQHLSILRRLVTLFQDESFVSKCQQFN-CQQTEELITQQ- -> ---MINIDNIYLDVKEENYKDILKKIGDILYKKGYVKESYTKSLLNREEMSPTGLPWSIAIPHTDP---EHVIKPCIIIFKLKNIVKFKEMADVNVKYVFGLVFTDKKQLPLLSNIISITQDKDAMEMLLNATTKENIFKTVTKY- -> ---MLSDKIILLDEAASDNQEALGQIADQMTRSGAVKDSYKSAVLKREIDFPTGLAIGIAMPHTDA---EHVNYDQLGVLRLREPVSFLQMGRIQVKFVFMLALKEHTQLAMLQKLIALIQDKASIRQLLLAEKTDEIVETLNNV- -> ---MFSEELIYLNESYHSQNDLFNRISKDLFEKGYVHDSYQEALKQREIKYPTGLQCGIAIPHTEA---MHIKKQAIAVVKLDETILFKEMVDVSIKLLFFLLVKEESQVQVLSNLMSLFSNNQFINDLLQSESKIQILETINNE- -> ---MLSKDLVFLDVEYKTSDEFLKSIADKLFEKGYVKESFKDAIIKREEQYPTAIGYNLAIPHTDS---EHVNKPGVAFVRLKNECEFKEMCDINVNMAFVLLVTQEEQVSLLSKLMELFGETEFLESLYKEQDPSVIVDVLNNK- -> ---MLKKEYILRDMDCSNSEEAIRMLADVLEKDGAVKDTFCKAVVDREKEYPTGLPFDVAVPHTTD---SHVNRPSIAVGFLSKPVMFRQMGELYPEVILMLAISDEKQLVLLKKLMVFLQDENALKSLKASSTKDEVYEIVNSY- -> ---MFQKEDIYLDVDAKNYIELFEKMAKVFKEKRYVKETYLKSVLEREKKYPTGFEYNIGLPHTDA---EHISVQKIILIRLKNEIEYREVVKIPIKIFIMLLIKNEDQTTILGKLIEIIGEKEFYRKVSEAKDLKELYE------ -> --SILDISGCKLKMTAGNRNQAMEMMAGLLAENPAARQALLEGMLQREELGTTAVGNGVAVPHCRL---DEMKGFALALSVCGKGVNWNSLDGRSVHIIAAIAGPSEEHLRLLAGTARVLGNGRARYELLNSETEFAMREAFL--- -> --NYLSPESCTVQLEGRSKAEVLSSLADLICRSPDLREAVLKGLLERETMGSTGFGKGIALPHCKV---EGMERFALALGISSKGVSFDAMDGRSVHVFCAIVGPPEMHLRLLAAASRVLGTGNSRYEMLSSTSAYALREAFL--- -> --QLTEKKCCKLGLKGRTKEEVLRKLAELAHKSEKLQDDVFEALQKREEQGSTAFGGEIAIPHARL---DEMDEFLVFFAVAPKGVEFDSLDKKKVKLIFVILGPSNEHLQILAAISRIAGIPAIRNEILRAPTETAMYEAFI--- -> --DILNRDLCRVRLHARRKEDMLNEIAEILKEHDALQEQIAAALREREQLGSTGFGDGLALPHCRL---PGLKQFVLGIGLSPRGAAFDALDGKKAHLFCFLAGPENEYVKVLAEISGVLRNESARRELRKAPTATALYESFM--- -> --DFLSEERIRPALRARERVGVVYELAELLALRGPVQGVLGRLLLERERIAGTVLAGGVAIPHCRL---EGLPRITACVGIQHEGCFFGEPEEGRVRIFVGLVSPMGLHLNLLARIAGMLREPSLREELLATPTAAGILQLLVQ-- -> --EHLSEDCIVPTLWSGDRKGVLHELAGTLAASTGAPRKVEGLLQAREHLCSTAIGEGIAIPHCRV---ERLRHVTACVAVHRSGVDFGARDGLPVRLWVTLVSPAGAHLRMLARIAALLRDARLRQSVLAAPSAAAIRSLFIR-- -> --HLLLPEHVLLDIPARTREEVLYFVAQALERSGLNSEDLVDHLLEREKLGATVVGHEAAIPHCKL---PSLKQVVVAFARTQEPVPFGPEPKDRARFFFFVLSPPAAHLQVLAEIARLLRDRDVEAGLAKVKTPQELLVLLAK-- -> ---KENEKFLYYSFDEEEKEALLAEMSAVLIDAGFVYESYQPAVIERERVFPTGLGLSVAIPHTDS---DHVKKEGFLVGVLEKPVRFEMMASLEVELVFMLAIKEEDQLAMLQKLMLLCQDEKNLQLLKSKEKVVEVEQLLKTI- -> ---IFHEQFIYPKLSGTTLKEILDKVSTDLLIQGFVKESFSQAVLEREMHHPTGLKIGVAIPHTDS---SHVTQSVISVITLETPIPFTIMGSTNVQVLFLLALQDKQHIQILKEIMKLIQHPQRLQQLATAATKSEIIESISTL- -> ---KFDEDMIMLNICASSSKELLKELSQVFYDRGYVQDSFKQAIVKREEQYPTGLSIGVAIPHADP---VHVKQESLAVGILSDAVIFNEMTSLNVEIIFMLAITDGQHLIMLQALSEILKDKEKLSSIRYAATKEEVFQCILPY- -> ---TNEKNIFV-NMEVADFPELIHKIAQPLIEDQDVVVEFPTQVIKREEGFSTGLPIGVAIPHTDA---KYVKNNRVTIATLKNPIKMEVMGGIDVSIVFLLALGQNKQLNILKKLMGILPDAELLKKIKNGTK-EEIYQLAKDE- -> ---YFLVEECYFDVRVQDFAELIAKFSQIFITKGYVNVDWAQSMLTREKNYPTGLAHCIAIPHTYS---EFVQTSLIVPVVLQQKIPFVHMG-IDVEVIFFLLIKEHQQVDVLAKILNLCSQKNFITELKTAKTQTTMYETVLRN- -> ---YVYPELIWVNKSFADKEDLFKTVAQSLYNKNFVTETYYESLLAREIKFPTGLDYYVAIPHSEC---GNIKKEFISVVVLEKPVTMNKMD-LPVEYVFFLGMNNQDHLKVLKEVITIIQNKHLILEMKKTSSPDQIAGLLTKT- -> ---FNEKLIFKLSDEIDSKEIALSFLAEQLYAKQYVTEGYKKGILEREKIYPTGLGINIAVPHTDC---IHVRCDAFAMGVLSKPLTFYAMDDIDVNIIFMLALSQHGQIAMLQKVLALVKEQEQLKKMINCKDVKTIYDICLKY- -> ---NNVTRCLIKGMEFNTRKEVLEYIGNYLFKKGFVKESFIYALLERERVFPTGLNINVAIPHTDA---DHVINPAIVVMVLNKPIVFETMGSVKVDVIFALAIQDKKQLSLLQKLMELFQNEERLKHLIDVSDIEEFEQIFSIE- -> ---ILSNIEVLNLNHATSREEVLTVMSKVVIEKGYATPGFLNAVLERERNYPTGLGVEVAIPHADP---EWTLKPSLTVGVLQNAVEFEPMG-VQARLIFLLTIADSEHLNFLKAFATLVEDEDTLVEFEKNPDIHYLLGRLQSA- -> ---EFDPGIIRPNVNVNNWEELLGKMGDLLKEKGYVKETFKEALINREKEHPTGIELGIAIPHTDA---VHVNKTTIAMVTLEKPIKFELMA-TNAEIVFILVVKEKTQLFFLKRLMAMFQKIEVLQKIKEMKESKDIINLLKQE- -> ---V-QTDHLFIFPDETRQDVILEIMAKSLWSKGFVHESYVNAVKDREKHYPTGLADHVAIPHTDA---CHVKQQTIALGVVKQGTKFHCMADISVKLIIMLAIEKEAHLEMLEEIMTFIQDASRLEALSQASTPIEFFSVIQPA- -> ---YLDEHLVDLEMDE---FSALAALADRLEENQCVNGAFSLAIQEREKEFATGLHIGVAIPHTDS---EYVFKQSMAIGILKQPVMFEMMGSVPVKIMFMLAIKEKKQLEFLQALIDMFQTDEKVLAIIQAKSAAEAVKKMKQN- -> ---YLDEQLVDLAMDE---FSALATLASRLEANQCVNGEFSSAVQEREKEFATGLHIGVAIPHTDS---EYVFKQSMAIGILKNPVMFEMMGSVPVKIMFMLAIKEKKQLEFLQALIDMFQTDEKVLAIIQANTAEEVVKSIKQN- -> ---HFRRHYVQHLPQGLSVEALIHQLAGPLINDRMVVEDFASHVIAREAKFPTGLPVGVAIPHTDH---KYVRHNAISIGVLPKPVIFADMGGVAVQVVFLLALGENKQLNVLGLIMDIIQDGEFMQRLLAMDD-EEIYQSILTK- -> ---QLNVDLMMVQAVVGDQIDLLIEMGDRFVAGGYCKPMFTEAVIHRERLYPTGIRIGVAIPHADS---EFVIKEAVGFAILKEPVCFQQMGGLAVSMVIMLAS-MRDHIDLLQCIVSLLQDNVVLDRLLGATEENEMIQIIKKW- -> ---TLDRDLIVMDLQAENKETVIRAVVDKMVEMGYVGPDYYDEVIAREKDYPTGLGVMTAVPHAFC---STVKKTGIGVAQLRTPVLFQNASDLPVKLVFVMANAQGEHLSGLQDLMDVFCKKQMLLDLYASKTPEQFMEIMESG- -> ---LVHKENIMLNLSATDKESVLSQMSDVLFQNGFVKSTFKDAVIDREKEFATGLLCSVAIPHTDV---EHINHRTIGVAVLEKEVPFIEMGTTEVKIVFMLAMDKDDQLKLLQQLMQIFQSEEKLEQILRTKDETILATLINDY- -> ---NIEKGYLVAKVAATDKFGVLREMGNVLVEKGWVKDTYPGAVIEREKVFPTGLAMGVAIPHTDA---IHVNKKAVFCGILDKPVDFVVMGDVSVEVIFMLAIMKNDQIEMLSKLVETCQNVSVLQTVKAAEDMDTIEEVMEKL- -> ---YFKEEMVLF-SNEQDKENLLSEMAEQLIQVGAVKPSFKEAVIKREAVFPTGLHAGVAIPHTDS---EHVIRPVIAVRILETPVSFIEMASIEVKVVFMMALKSDEQLDMLQTLIQLIQDEEVMTTLLEAKETTNVLTAIEQF- -> ---MMDTSLVFLDADFSSRDDLFHTMGSWLKDNGYVNEDYREAVCRREEEFPTGLGHQLAIPHTDS---EYIEKPGLVFVRPKNPLAFQEMC-VDAEMIFLLLVKDKDQMPLLSGLMARFGDGELMDRLSRETDPEVIADLLDHC- -> ---FASELFVSLDVTKENLQELYQDIGNELVEKGMVMSDYGEQLQQREANFPTGLFGNVAIPHTDA---KYVKKPFVYAIRLTDEVITKRMD-IPVKLLFVLGFTKEDQLVLLTKMMQALNNESISNQFQQVDSPERFKEVLKEQ- -> ---NTDKHYLAVSLSGSDDKEVLGKMAEAMFQEGYVTEGFHDAIIQREENFPTGLEINVAIPHTDP---EYVKKPAICLGVLDQPVEFCVMGMTRVSLLFMLAIKKEDQLGLLQKLIEACQDQEVLKVLRSGS-VDKIDEVLGDL- -> ---LIDAELVRLHMVAQTPAEVLGKLADTLFGKGKVKESYKDAVLQREIQYPTGLGTCVAVPHTDS---SHVLEPALAVGILQQPVAFQMMGSLPVEIVMMFAVDKEKHLTVLTQLMTMLQDETLLTKIKQATAATEVCSLLSGL- -> ------MEFVFISDKADNWEDAIVKTSRALFDAGFVTEEFGSQCIKREREYPTGL-IPIAIPHTDS---AFVHTSAICVLALESQVPFINMEDVPVEYVLNLAIKDKNQVTILNKVLQVFNREGLPEQLERKGN---IMQAFVNA- -> ---IFKKDLVDLSTNAESAEELFRESFAVLKNKGYVQDDFLEALNKREHDYPTGLNIAIAIPHADP---QYVSKPFIYIQKLNNKISFKHMG-IFPELVFTLGMKEEKQLELLSELMEFFTNEKIVEELKSINNEEKLLYLLSNN- -> ---LKKDYIYDL--RAESRDKLFEIMGGRLEKEGITKNSYVAALKEREEKYPTGLGLLIAMPHTDS---AHVNEACISIARLENPIPFHEMGNLDVEMVFMLALKDEAHLKILQKIIGMFSDREVLKKLREAETAEKIYQVVYEA- -> ----MNENLIFLQSGIETAEEALTYLGNRLREQQFVKDTFVSAIIERENIFPTGLGYGVALPHTDA---KHVTQTQVAVMTLEKPVTFTQMASVAVQLIVMLAIKEHSQLEMLQTLMGVLQDRDLVQDILACRAQDQVLELLSSH- -> ---EMKTRYLVIHGTADNNEQAIKLCGEALYKAGIVSENFGDLCAKRERDFPTGL-IPTAIPHVKD---EGITENAICLLKLNHPVTFKRLDDVKTDMIFNLAIRDDEHLAVLQKMMAFLNNPEVLTKCKKLSNEETLES------ -> ---FVNKDLVFLNQEFDTNSELFEFVGAEANDLGVAKESYADALKEREANFPTGLNFGVAIPHSDS---IHINEEFISVVTLDKPVQFSSME-LDVRLVFVLGLKKEDQLSILQAIISVIQDESKVEKLISAASSDEVLEILENN- -> ---LVIPELVFFGESFDDQEDFFKKSSKKLLELGYVTEGYFKAVVEREASYPTGLNISIAIPHTNP---EFIVNPFIAAYHLRNAVAFTQMA-IQSELILALGIKEQEQVGMLSKIIEVLNDPEFVKEYQSLSNQEQLVKLLKSK- -> ---ILNKELVKISLDAEKFSDVIETLGSLMYKQKSVKDTYINAVIEREKVFPTGLGMCVAIPHTDS---IHVNKSCMAIATLKNPVEFSMMGNLSVNVVFLLAIKDNNQLMLLKNLMLLIQNGELLNRLKDAESVDKVLEVLQFC- -> ---L-NKEHIVIMDNCEDWEKAIRLLGDRLIRTGTVGREYIDRVLEREREYPTGLGGNAAIPHADS---AGVFRPGLALGVIRQGVGFREMVSVRVQLVFLLAAVSEGQLGLLQGVMELLQNRSIRERILSAEREDQIAGILGKR- -> ----MKEPLLYHRLSVATQRELFEKLSTELEVEGIVQQHFLEALIERESEFPTGLKIGVAIPHTDG---TYVNEDRLVFVTLEQPIPFNEMGGIEVSVVIMLAIKEKNHLSILQKLIESLQKEGFVEQLAQAEDVNKMETVISAY- -> --LVIKRELLFSKMKPQDYEEMISFLGGKMEELGYVKNTYVPAVLEREKGFPTGLQYGIAIPHTDR---EHVYQSALAIATLAEPIEVCSMINVRVSLVILMAVEDDGQVKMLSKLMGLFQDVETLKRLEHASSVEEMYNIVAKM- -> --ILFDSDMVVVGQPFPDPEAVIADLAGRLAARGCVGPGFLEAVKDRETRFPTGLPVGVAIPHTDP---EYCLRPGLAVAVLPQPVPWRAMGTVDVRVVFLLALPAQKHVNFLSQLVQLFQSPDALTQLISLSDPAAVADFVRCR- -> --EYLQYSPILLGEQYQNKKEVFTAVYNLAKQKGWVTKDFGKKILEREEIYPTGIDFGIAIPHTDP---EWVKEEFITLLVPERPVLFQRMDDVQVDFIFILGLNQHEQLAMLQNLMQLIQNTALLENLYKQTKREKLILLLQDY- -> --RMVYSELILLGLDVPNAEEAIRRLGARMVDYGYVRETFVDAVIERERTFPTGLPIPVAIPHTDA---VHCCRPAIAIGVLTRPVTFGEMGNVDAKVIFLLSITDSQQVVWLQKLVEAFQHPHFLQHLVKSRNTEEARSICQEV- -> --ALLNKNLIHRNATFLDADDALKSMATTMVKNRYVKASFVDAVVNREHQFPTGLPIMVAIPHADW---TNVNRGTISVATLKEPVVFKNMGDLAVRLIFMLAVSEHAEVTLLKDLMGIVQNQATLQGLLDAKSDDELFNRLEDM- -> --DHIEHEAIALNVEATTSEAIIRLLADRLARLGHVRPSFAEAVLAREAQMPTGLPANVAVPHTDP---EHVIRPGIAIATLARPVDFANMESLPVGIVFMLALNDDRQIEMLQQIMETIQDDDLVDALLAARTNDQMLALLGRG- -> --LYLNEELVFRNVEASTDSEVLAYLAGELYQKGYVKEEYIQAIQDREKEYPTGLPPGIAIPHANY---EMVNKTTLAIATLKEPVLFHNMEDLPIQIVIMMAIGEHGQVEMLQKIVGIIQDEPLRQEMIDARNDTELLALLKKA- -> --ILIDADLIEINMDVSTKEDALLSLSNRLLEKDLVEQGFYQHIIEREEQFPTGLPIPIALCHTEA---IHVKKSALAVATLKRPVIFQEMGTLDVEIIFLLALKDKDQVHWLKKMIGVFQKEEALHKIRSASSPNELSLYLSQV- -> --EIIMRDLTALDLDAKSCEQVFDIMGARFLEKGYVNERYLPTIKEREAQYPTALPYPIAIPHTMA---DAILKPFIAPVRLKNTVKWGDMSDFDVKLVCMLGFKDGEHIELLQILMHNFQKSEWANPLFSAKTEDEFFEAFNSM- -> --QFITKDMIWVQTPCRDQDALFEMVSERAASQNRISNQFLEKLTEREAVFPTGLQYGVALPHTDP---ECVTEQFIAVLTSEPGIRFKQMADTRANLIFVLGLNEHSQLAVLQQLMGAIQNEKHVKELLAAKNEDEVIETLSQV- -> --DYVKKDTIFLNCQAQSRAELFSKVSDKLLNEGYVKKGFLDFINHREDNYPTGLQHTVAIPHGDP---QFINKPFVAVITLTKPITMRRMDDLPVDTLFTLGLTNSDHLDLLKEIMKLLQTDSFVQQIKNCTNKDEVETVIRVA- -> --FALVPELVLVGIEASNRCEVLATMSGNLFRQGYVQESYIQAIQEREVHYPTGLPIGVAIPHTDA---VHVNRAAVSIGILKKPVLFQMMGNIEAEIVFMLAIKEQEQINMLQKLSSLFQNRTLLSNLRKAVEREQAVSLLNQA- -> --QIVRECILPH---AQQKEDIIQELSKRMKERNLVNADFQEAVLKREQKYPTGLLRNIAIPHTEP---QYVKVPCIGIATLKKSVAFHRMDAVDVDVVLLLALNQHAHMEMLSRIILMCQDEAFIEELMRAEQETDIEQIVRER- -> --DYLRDELILPQRELTAQQELFRFVNEVALENGYVNEQFLPKLIAREEKYPTGLEGAVAIPHTDA---DTIVKEFVAVITTKEPIEFHRMDDVRPRLFFVLGLNRHAQVKMLQQLAAVIQNHELVTLLEQAPTPEAIRATLE--- -> --PFLKEELLKLNSVCKDQADIFEMVYKEAFGKGYVSENFLTKIKEREASFPTGLQYSVAIPHTDP---EHVFEQFISVVTLQKPVSFYLMDDVDVRIVLLLGLNQHTQLTVLQELMQAIQDQQKIEQLLQAENQRDVQAIFNGV- -> --SLLKKEMVWLDACFENRLEVFEAVGMRAQHLNLTEETFSTQLELREKEFPTGLAYGVAIPHTDA---VYVKEPFIGILTLEKPVIFQAMDDVEVRLVFVLGLAEHTQLAVLQELMKIIQDKERIKKMLSTQTIEEMLATFHQE- -> --MNIKPEYMMLNIKASTDVEAIKILAENFFKAGAVKDTFVPAILLREKNFCTGLQAGIAIPHTDA---IHVNYPAVAIGKLENPVVFQSMGAVKVEIMFMLAIKEHKQIEFLQLLMTKFQEENLLRRLMKCNTAEELTEKFIAC- -> --IKIFKEAIHTHLNVNDKAELISILAKPLLEKKYVTAEFAEKVLEREEKFPTGLPIGVAIPHTDP---KYVLKNAISIGVLKKPLPFKVMASVNVGIIFLLALNDEKHLEILQKLISLIQNEKALFQILNGSKDEIFHFIDRQL- -> --EDLDKKLIHLQAEAGHANDIFDQLGTCFINEGYSRSDYVEALKQREAQFPTGLDFGVAIPHTDA---GYVLHETEGIMTLKHPVTFIQMGSVEVKVVFMLAIEDKNHIKKLQQILRIIQDNAVLEKIYRASSADEVIDIVKQK- -> --QLVREDLINLQVKANDKSQLLEILSDDLYQKGYVLDSFKEALIKREREFPTGLQIAVAIPHTYA---QHIRAPFIYINQLEAPVSFIQMGTVQVSYVIILGISKQEQTGLLAELMEIFGNADFINQIQMVNSKKDLYNLFKTQ- -> --EYIGKDHIRIFEESVDQSELLHQLGDMLIRTGAVRIEYMEAVCKREQAFPTGLYVNVAIPHADPE--HHVMKPTIALGVVRKGVPFRNMADISVQLVFLLAPERETQLVILEQIMNLIQDQANMRKIMDAQGIEDVWNVLGQL- -> --SEYFQIETIFSEQ-TNQTAVLCEMAELLIKKGYVKESYQDAILKREKTFPTGLMGGVALPHADS---EHVLAPIVCIAKSKEPIYFHEMAVVPVHFIFMLALQDSEQLDMLQFLIQMIQNEEVMDSIANSEQATEILDAIHAF- -> --SMINPELVFTDLPCTDRQTFLQYISRRLEEKDYVKCSFEGAIIEREKKYPTGLPQHVALPHTDV---QHAKNPIIVPVKFRTPVVFKEMGNIPCSMAFVLVVTEEKQIDILQSLINLFIKKDFLEELYKEKTREGFLKRLLDE- -> --AITSEQLVWIQQDFTSREALFSFMSQQLYEKGYVNEGYQEEIISREEKFPTGLVYNVGIPHCDS---QYVKKDFIAIVILSNYIQMNQMDKIPVKYLFFLGLQDNNHLKILKKIMKVIKSEQLIHRAENSQSVKEISELLKIE- -> --ISFDVSFVKHIDDGFNFGQIIDELSKNLLDKKLVTKEYPQAVKDREIKFPTGLPVGVAIPHTDP---KYVINNAVSVAVLKKPIEMTVMGTVEISIIFLLSLAQNKQLNILKRIMSVVQDQDLLQSFALASN-DEITRQVRKA- -> --DMISEKLIIFSNKANKKEDILLEMSELLSKNGYVKNSFYDGIKNREESFPTGLIGNVAIPHTDS---EHVKKPAIAVAVLKSPVNFYRMDDIEVDIIFMLAIKEENQVGVISNLISAFKGSNLLGDLKKSNSKEEAFKYMKNN- -> --LKFEEAFIYPKLDAKSYEDAVRKMSQNLLKEGYVTSEYPDQVLAREKNFPTGLVMNIGIPHTEA---EYVKKTAVAVATLREPVKVHSMIDLPVSMMFMIAVSDKGQVTILRELMRLFQDQDLMEKIMSEDTASGIYKLLKPN- -> --SIYYDAVI--LEDMNSKEEIISCLANYLQQKGYVNEQYQAATLERELEYPTGLPIGVAVPHSKT---ENVIRPAIVMAISRKLVEFGEMGNLQVGIVFMLALQGNRHLNFLKHIINFCKQESNVTRLYQVPAREEAYRIFQEE- -> --HFFSDRVIIFDQTFSDRNTALKSVADQLLKAGAVVPTFEKAIIAREQTYPTGLQIGVAIPHTDA---DQVIHDQIGFVSLKTPVEFRQMASVSVNYLFVLALKTHQQLDMLQKLMGLFADDAEMTAFRKIKTADDFIHFMTEQ- -> --SRIDEKLVKVGVQVPSREALITAMGTMLVEQGFVKPSYIPALLAREKEFPTGIAVGVAIPHSDA---GHVLKTAASVWVLDKSIPFHVMGGLEVNIVFMLAVHNQEHLMFLQKLLGLFSKEDVMLKLRNAANATCIAETINLE- -> --ELVKKKLVFPNIRVDTHEELFRFMFTALQDAGCVKQTFLQGVLDREAHFPTGLKFGCALPHTDL---EHVITPAIAVATLKEPVLFKSMEDVPVNLVFMLALNKEDQLLALKQLASIIQNDALIKKLIDANDQESLFSAILEV- -> --DKVREDLILLNVEGDTRDEVLNNISIALLEKGVVKKSFASALIKRENEYPTGIPYNVAIPHTYP---EHNNEIAVTIAVPKKPVQFYNMGNLKVYVIICLSFEKDDSVKMLSSLMTFFGNEENVKAVMVCRDTSEVLKVIRSS- -> --LFLEREMIFPKLEFDSRTEVLQYMAHQFTKLDLAKESYAAALIEREAHFPTGISFDIAIPHCAS---ENVNRTSMAVATLTHSVGWHAMDDLQPTVVFMLAIKDDKQIETLQKIMEIIQNSQLLQDISVAVTRDEIFSKLDPI- -> --DLLAPTAVCVHLDAADWRAVITALGQRLHAAGCVRATFVQAALDREAQLPTGLPFNAAIPHTDI---EHVITPALALATLARPVEFRNMIDVPVQLVILMAMEEKSQVEMLQEIAGVLQDPDLIAQLVAAGDEVAIRRVLEGV- -> --AYVKEPLVFTQENYFSQDELFEQVTQKAADLDWVRDDFLERIKKRETTFPTGIQYGAAIPHTDA---ECVHEEFVAIVTLQDPVIFQSMEDVKAQIVFVLGLNQHAQLEMLQSLMGLLQNESLLAELLLATTPSELIEIIKQN- -> --DLVKDELIDIAQEDLEYKEVISYLGNLLLKNNYIKEDYIKDVLLREEIFPTGLEMGIAIPHANP---DNVLKNGIAILKLKNPVRFSNMETVYVNIVFMLALKNDDHLKMLQSLFLMFQKEEVMDELGKVQSEEYIKIIMLKN- -> --NYLNENCILLRPEVDDKFKLLGNMSDLLMREGYVTEDFGQRVIEREKVFPTGLPVGFAIPHADV---KYVKKSGLCIAILDKPISFFRMDDIDIDFVVMIAMKNDEQLKTLQSLIDSFNNIEGWLELRRVSRVQEAIERLKEL- -> --VYISPELILMNIEAKTDQEAIEILAKHLYEKGIVKESYIDAVKEREKVFSTGLNMGIAIPHTDS---IHVNRQAIAVGILKEPVKFCHMGMVKCEMMFMMAIEKESQVDFLGRMMDIFQSEGYLRGLKACATPEELAEKFGKS- -> --ELFHQHLIFSNLKCETAYQLFEKVGSCLHKENYVKSSYLSALTKREETYPTGLSINIAIPHTDC---EHISSPFIAYANTEKPLPVGSMGELQVSHYFFLGITEKTQVELLQYLMTLFTNHQFVQGLKHAKSEEEIFQVIKYP- -> --MFFDEKVFEDIQGLESSNEVLQHLSDKLESLGIVKNTYKQAILKREEEFPTGITYGIAIPHTDA---EHVIKPQIGVMTLHEPVEFVQMASVEVNTIFILALKEHSQIDILQKLMTLLQNTEVMEKINQLKNTDEDKEILKEI- -> --TLFQKELIKLNTEFHSSDDMFVALSHDLIKNGYVEDTFNQAIIEREKEFPTGLSALLAIPHTDT---KHITKPFIYVVKANKPMKFLQMATLEVNIIFMLGIKDAKQVGLLSVIIDKFKDEQFVHTFQSISNEKEMLAFLKNN- -> --DYLDENLIFTNKSFSTSKELFETISDVTLALGNTREDFLSRVIDREANFPTGIQIGVAIPHTDA---ECIFKEFVAVVINQSPIPFKSMEDVQASLVFVLGLNQHEQLEMLQSLMGLIQNEKLLFKIVAATSAEEVLTIVKTN- -> --NLFREDLLFVDMNSDSLEDVVKLIGKKMLEKGYVKESYVEAVLEREKKLPTGLEGGVAIPHTDR---QQVNESVIGVATFKEPISVYSMVDIHANLVFLLAIKDDGQIEVLKELMNLFKKPNLLKKMVEASTQKQLEDVTLNV- -> --GLINEHLVFPDQQFADNEAALRFLAGKLNAAGKVHDDFFDAVWAREQKFPTGLPINVAIPHADA---KYVKESAIAVATLAQPIPFHNMAVIPVSLIMMLAIHEHGQVQVLQNVMALFQDEQHLAQLLQEHDAHALFTDLDKT- -> --IAFNESLILEFDKPMTDREVLSAMTDYLCEKGIVKDTYKQAILEREQSFPTGLKINVAIPHADI---CHVNEAAICVAVLKTPAPFRAMDEVPVSLVIMLALTEHGHIEMLQRIVKLIQNQEDVKHIVEAGQPDTIHKIIKQY- -> --VIVPKIIVNTRLQVGNCKEIIERLGVQMLEAGYVKDTYIEAVLQREDILPTGLKVNVAIPHTDV---THVNESAISMTTLNRPVKFYLMEDIDVDIVFLLAVKEEEQVQLLKNLIAIFQNEELLAQMKDIEDENSLNQVIKAS- -> --ELLKPELVFFDIEAKDAFELFDQLETRLTNLGYIKDTWKDAISTREKNYPTGLAGEIAIPHTDP---VNLEKPYIAIVKPSSTINFEPMGGVPAKLVVNLGIMRGGQVEMLQSLMGIFMDEAKSADVFGQTTADGMVASFSKY- -> --DLLKRDLVRLDWEVKDQEDFFDRIATELLRAGYIRESFREALVERERKYPTALPEAVAIPHSDV---EHIIRPFIASVRLAKPIDWREMGNHPVRFIFVLGFVQDRHVEVLQIMLQAFQDPAFMEQLSEAQTPDEYYRVLSGM- -> --LAKDSLLTIIGMPQQDRYEVLKVLSDSLKEQGFVTDGHYDALLKREMHFPTGIPFGIAIPHTDP---AYVRQAAIAVGILAHPVVFYQMGAVEVQMVFLLALTQNKQINMLQNITRLIRDGEALAFIRHSTSREEIRNKLQSF- -> --ELIENGKVY-FCDFTSRDDLYAYLADDLYAQDYVQDTFLSALKEREATFPTGIIYNIALPHVDA---VHVKKNALIIAVLNHPINYVRMDKINVKVVFMLLIKDSVHTQAISSLAKLWFNQTFMNAVLSVKSKEELVALVKQA- -> --VELKKENILTNLNFQTKEEVLRFLANHLYEEGYVKEEYKKSIVEREHRYPTGLPVNIAIPHTNH---DLVNETTIAIGVLDKPVSFYSMEDLDIQIVIMLAIGEKGQIEMLQRIVAIIQNEALTKKVLASDSTETIVALLEPA- -> --KFIPELVET-NISAKNKEEVIRFLAKKLADRKCVSSHYSELVLQREKEYPTGLIAVIAIPHAFD---PETKGNNIAIGILKTPVGFKHMEDVPVKIVFMLAINGHEHMEMLKILMQLVRDEELFKKLQSISSKNEICKLLNEY- -> --EILDTKLFHIRLDVKDRDELFETMASGLVDSGRVKPSFLRGLMDREEIFPTGLPGGVAIPHTDA---EHVLLDSISVATLIHPVGFREMAGLPVDVVMMLALADGSHLDVLQQVLGWVRDGEFIDRLRGCLDEEEAFTLLAGR- -> --DYLVPDGVVLGCDAVDANEVIGLLADHLQKAAIVKSTYGAAVISREAIMPTGLPFAVAVPHTDP---EHVISSGVAMATLSRPVMFGSMDDIPVSVVFELALRSDEQIEMLTAIGQLLQDEGRLRRLSNATSKEEVTSILNST- -> --CYISKDLLFLNTNFSSTNELFQAVSKRGLKYGLVNDKFLPSIVQREAKFPTGLEVNVAIPHTDV---DTIEHPFIALNTNSQGISFCRMDDIQARVIFILGMKEHAQLELLQSLMNAIQNPNTLNNLVNAQNFDDVLKVLQDY- -> --DMIKKELIEIDFDVKNQNEYFEKMAKKLNELGYVKDTFLEAILKREEKFPTALPYIVAIPHVEP---EHVKKPFIAASRLKNTIEWREMAALNTRFVFMLGFLETDHVNLLQVLIENFQNEELMDKLIEAKDKEKFLELLRAI- -> --MLLRKDLIRIGLKGSTSEEVERNFAAVFVEAGVGKSNYPDAIVAREKDYPTALPFDIAIPHTYA---EYVNEEAMGIAILEHPVEFKQMGSLYPQLLFMLAIIDKNQLKTLQNIVKIVQSDDLLFRVKNAKTADEVYDILEPA- -> --IVVTEKSILRNKEFDRREELLKELSSLLLNQEFVKGNFYEELVKRENEFPTGLNFGVAIPHTDP---GVVIKDSIAVAVLENPVQFGEMTNVNAKVVFLLALTDTKHLKVLQKIIKIIQDSNLLKSLFIK-DEYEMSNFLNSY- -> --SLFRKDTIFFDDKEYTDKEVLHIIGKKLLDRGYVKESFGEALLEREANYPTGLAYPVAIPHTDP---GHVNEPCISIVRIKQGAVFHEMVNVKVNFVFCIALQVDKQTGVLQYLMQVAGDDSIMNIIKNAKNADEIYKVVSIK- -> --EYVKEELILLNLDISNRNDLFRQLSEIFQERGYINEGFYDFIVEREENYPTGLDHTVAIPHGNP---EYIKQSFISVVTLQQPIKMKKMEDIDVAVFFVLGLSDTQHLQILKQVIGVIQQETFVNRIKAAKTSEEVMKEISAI- -> --DLIDKRSVFANLEVDSSDQVIDVLSKSLFDQNRVISSFGDAVKAREIEYPTGIPITVAIPHTDV---KYVKQASLAFATLKKPVAFRNMGDLDVQIVVMLAMVEHSQVTVLQSLMSLFQEQDYLKELLTLDKQEDLYEHISKY- -> --LVFDENLISTQLEASDNYDAMEKLGNILYTKGYVKDTFIDAVIEREKEYPTGIQFNIAIPHVDN---CHVKKPGIAIGVLKENVLFSRMDDLDVKVIFLLAIKTEYHLEALKEIMNLVQNAKAMNEICQCKNSKEIIKIIKRE- -> --ALFTPELVFFDWECATPDEVFARLEGELAPHGYIASGWLDAVRTREDAYPTGLAANIAIPHTDP---GFVAKPYIAVVKSAAPVTFNAMAGVPAQIVINLGIAEGGQVEALQALMNIFMGADAAADVLGQTTPQGMVDAIRRH- -> --NISKS-NVLLKHNCDTRAEVIALLADSLFASGKVKASFKQAVLEREESFATGLEICVAIPHTDR---EHVISDSIAVMTLNSPVGFNAMGTVSVRIVFMLAISSDKQIDTLQEVIDVVQDQELLSKLLCASDYQEFVDYLNVI- -> --MFFNKEIIKFNFEGHSKEQVLSHLSEKFIENDLVTQDFYESIISRELSFPTGLWTGIAIPHTDS---EKVKQAQIGFMSLKQPVTFKEMANIEVSLIFMLALKQDQQLSMLQKLVNLFQNESLVKQLKECTSLIEFKSIMKNA- -> --VSFDSDFARCDLDVATQEEIFEELARPLVAAGRVKGDYASFVQSRELRFPTGLPMGMAIPHTDP---EHVIAPAISVATLCNPVEFHVMGSVSVSVVFMLALDDHAHIAFLQRVVRFAQDKALMSQLINATTDDDLYQLVTGS- -> --KGFHEGMIMISTQGKSKQEVLTELADHLQATGYVKESYADGILKREEIYPTGLSINVAVPHTDC---AHVNQDAIAVGLLDDPVIFQAMDDVPVSIIIMLALKEHGQIDMLQKVIALVKQQNDLKRMLTSVDTKDAYQVIAHY- -> --SQLLNEKLMVPLRADGREEAFAQLAQGLQHYGYVKDSYFKALLNRESTFPTGLCINVALPHTDV---EHVLQPAIAVGVLEKPVRVASMDNIDVSIIFMLALKNHDQPKFLEKLVVLFGNKVLLRSLSAAKDVKTAYRLLLAA- -> --ILIDPEYVFTELDAETRQDVFEELGGALLADGRVKDDYIAALAEREEGCPTGLPGGVAIPHTDA---SHVNQDTIVIATLAKPVAFREMGGVEVSTVFMLALASGEHLEVLQKIVKSIQRPEFLETIRSTTDPQVIADTASEA- -> --QFLSSEHIIVTEEVVGREQILTQLGGRLVQSGAVADEYVPTILEREQQFPTGIEIHIAIPHADA---AYVRKPAVAMAVVKKGVSFRSMADLPVKIVIMLALEKETQLRVLEQIMSFIQHADRLQELVEMESGEAVFRALKQS- -> --ILIDEKYIHIDCEYDNKEDLLKYLTDTMLEDNVIKNTFYENILAREFKYPTGLNIKVAIPHTNP---EHVNEAAISIATLKNPIKFNNMENLFVDLVFMLAVDNEKQVPLLVKLMGIFSQSDKLKEIKESKDKSEIKKIMEDL- -> --DLLHEELVFLDVDARKTEDLFLFVGEELEKRGYVKSTFTRAIIEREALYPTGLAINIGIPHTDP---MHVNTGFVAVVKNKYKLPFIHMGTILIDYFFILGIKDADQVKLLQLLMEKFSNVEFIQGLQSNHEQHTLFSFIKNK- -> --RYCNQDL-ILFSTLSVKEDILSYMAACLWRHGYTKESYREAVLARERVYPTGLGIGIAIPHTDI---VHVIKPAICLCILKDPVQFGLMGGVRVSVVFMLALREEKQLEVLQMVITMLEQEHYLKSLLQCCSTEEALSVLVQA- -> --MTDAPRFLVLDADTANQEDLYSVVNSHLLSQEAVHETFLEAVSARELKYPTGLDCQVAIPHIDP---EHIITPGVLVCRNAQPTPFHAMDDLDVRLTIWPLVTDQNQTGMLGAVIALLQEETSYQRLLTESPEK-LEELLAGV- -> --FSFDKRTVKARVKTNSHEEILRQLATMLYQAGYVAESFIDAIISREAIFPTGLPYGVAIPHTDP---HHVKEAMIAIATLEKPVNFKIMGNIEVTIVFMLAMRDSSQLQLLSNLMSVIQDIGLLKRIYASESEEELLAILNDA- -> --LSFDSSLVVIDEEGLSCEDVERRLAGVLEEQGYVKDTYAQAIVDREANFPTALDLNVAIPHCDV---VNVNKAAMCMGVLANPVDWHKMDECKVSVVCMLALTEHAHLEMLQKVIAFVQDQELVGKVIAAQDADEVFSLAGSL- -> --KLVSESDIFIDQEFQDEQEYFEVVTQHLLKEGKVKASFLESILQRERSYPTGLDIKVAIPHTDY---TNANTTQLVVTTFKSPVGFHQMDDIPVNVAIMILFNNEKQPQMLKYIMGIVQSQENLHEIINTKDVKSMKQLFENF- -> --IHIDDDLIEMDLKVDSKKEVIKKLNKKMLKKEIVKESYLDAVLKREEEFPTALSINFAIPHTDP---KHVNRAALAIALLKNKVNFISMENIEVEIVFLLAIKDSKQVKVLQKLMEIMQSKVIVDKILTAENQSKLVDIFEKR- -> --IIINEDLVQTDVIASTQNEIFEQLAKPLYDLNLVNEGFLEGVRRREQNFPTGLPFGVAIPHTDP---EYVKQNAISVGVLRHPVTFTVMGTTDVRVVFLLALNEQKQLNILKSITELIRDAKQLEKLLSCDSTEIYKILDSKL- -> --AFLNPEAIELQSNAKSNVEIIRILAGKLERLGYVKPSYADAVVARELSLPTGLPDNVAVPHTDP---EHVIRTGIAFATLTSPIPFGNMEFLPVGFVFLLAIDDNTQIETLQQIMTTIQNADAMERLKQARTLADVEAALA--- -> --EMFSEDNIYLGVDGNNFFEVLNNVSKELDKKKYINDGYIESVIEREKIFPTGLEYCIAIPHTDS---KYIKKDAIAIVKPKQSVIFRDMATLEVNIFLLLLISKENQVKVLSSVIKNFSDEDFYNKIIQNNDKKKILNIIKNK- -> --RYLDRRAVLVGMPAADHGEAIDHLAARLQEIGRVHPSWGPAARTREETMPTGLPLNAAIPHTDP---EHVVEAAVGLAILPEPVRFQSMDDLDVRIVFALAIKDAEQIPLLQAVIEALSDEKRLARLAAARNPDEAFTALES-- -> --FLDNRCIELK---YDSYEDLITNVSRELLKYGYVKESFLENILGREKQYPTGFEYNIAIPHTDM---ENVLKPVIYIVVLDRPVMFKSAEDISVDIVFVISLNEDKHIVVLEELMKIFSKNDLIEKIKNSEDKDELIRLIYEE- -> --LLIRRELIRFHSRQTSVEGIFREAYETLLEKGYVRETYLEALLVREAAHPTALAINIAIPHADP---AHVKKGGIMAVALEKPVTFRHMMDVEVEYVFFLILTNSSHLDALSRLMSIMQKKEAVERIRGCETEDELYEVLAEL- -> --NLFNKELVFLDIESPNANELFKIIADELQNKGFVNEKYHDGLINREKDFPTGLQYSVSIPHTDP---ETVKKDFIAIVRPRSPIMFSLMEDTPVDLCFFIGLRDKKSPLALMELISLIQNHKLILSILNEKNREKIIEKIQEV- -> --ENFKSELVNLNLNVNNQKQFFQVISNDLKEKGYVVQTFKEAIIEREKMYPTGLQFAIAIPHTDV---VHIQHPFVAVYRLKKAINFYQMGTVPVKDVLVLGINEKKQVGLLSNLMQCFSKNEFVKKYKNITTSDSVIELIKNN- -> --MQIDKELMMIGIDFQTKEDILESMGTRLHELGYVEDDFIENVLDREANFPTGLPYAVAIPHTDT---DKVIEPGIALATLKEPVPFSSMGNVGVKIVFMLAVDAGEQVTTLQNLIEMVQDEKVVSNLAAVRSIDECSKVLEDF- -> --NLFKKELLVSSLNASTSEEVLRQLANVLTEHGYVKASFSDAIVAREGIFPTGLG--LAIPHTDR---EHTITDAIAVAVLSHPVEFVMMGSCLVSVVFMLAMSSDAQIETLQTIMGYAQSREALEALTRSAGVDEMYQVLSEG- -> --TLVYSNLVNIENKSTSLIDFFESASRELVEENFVEESFFEAILSREQIYPTGLVINIAIPHTDV---DHIKKPFIYINKMEDDIEFTQMGSVIPEYVIILGIKEKKQVTLLSTLIELFNNSNFLDELQNCNNNDDLIKLFKNN- -> --NFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGEKILARENVFPTGLNYGVAIPHTDA---EYIKEQFISVCTFNEPVVFSSMEDVPVNLAFVLGLNQHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL- -> --LPIKLENIKLNQQYKNREDYLKKMGEQLLSAGLVNEGYSTSIINREEIYPTGLAINIAIPHTDY---QFSRTTDIFITVLKTPIAFFRMDEVEVSIIVQILFDNEKQPDILKELMEIITNQRVLKEMIAAQEPKEVLQHFQIN- -> --NFINQELIFFNSQFISKEQFFKETTEKLKALEYVEDSFGSAITTRELNFPTGLQINIAIPHTDP---QHVKKPFIAAYQLKEPVEFVQMATVPCELILVLGITDKNQVGLLSTIMEVFGNVEKVSEYRKIKSPKELHKFLQEN- -> --MFFNERIIELGMDAKSDTDVITQLARILTQKNIVKKSFTNHVLLREKKFPTGLPLGIAIPHTDS---IYVNKSQIAVASLKKPVVFKNMVDVEVSLVFMIAMSQHEQANLLSNLMNMCQHSQAVEDLIHANNENTVEKILRHY- -> --KLFSKEVILFHQDIATQDEIFEKLNENLLAKGVVNDGFLAAIKKREKNFPTGLKFGVAIPHTDP---EFVNEDQIGFISLNKPIQFRQMGSVEAKMIFILCLKEHKQLDMLQNLMTLFGDDAKIEKLYACKSIEEFLNLIS--- -> --EHLDDNIIFLNQSFYDRDEMFQFVSNELLKNGYVTGQYLEKVIYRENNHPTGFKINVAMPHVDS---EFVKKNGMFLITSKKGILFK--NEVLVQIVFGLLLKQDTHLNFLMKLASSFGNDQILQKIVESNSKVEIKNILKDI- -> ---MINEEFVYCNVDFSTSEEMLTTVSKDLFIAGFVTDMYGKKIIEREKKYPTGLKLNIAICHTDP---EYVLKNTLFFVRPKHAIKFK--NEIDVDLVIGLVFSSEEHLKILSFLAGLLSDSLCIHKIKESNTPKQLVMTMKEI- -> --MYLDKELCLFQLEVKNQAELFKVMSEQLVTNGCVKDSFLEGIINREKEFPTALEIGFAIPHTDS---IHVNNSQICFASLKEPLVFYDMTNIPVSLVFMLAMSQHEQIDTLQNLVNLFQNQERVQELLSCTTKEQFIEIVHSA- -> ---MAIDVIVSGQDTITTYQEAIRTAGEKLVEKGNIDAKYIDACIEREIDFPTGLLDGIAIPHGNS---DLVNKDSISVVRIKNTVEFGRMEDVGCSLVFNLALASNQHIGILRKLIGLFQDEEFVDTCKNEETDT-VQKYLLTK- -> --MYFDKRLCMFHQIFATQDELFETMFKTMFQAGVVKSDYLEGIKEREEEYPTGLLIGFAIPHTDS---SKVNYSQICFASLNQPVEFLNMGDIKVELVFMLAMSQHEQVQILQNLIALFQNKEAINVLKQCENEEEFMGILNRN- -> --MFFNEKIAQFHILASSAEEVIEIAANELYQRGVVKKNFLENVLKRENEFPTGLNYCVAIPHTDS---DYANRSQIEFVSLKEPVYFKNMANIPVTLVFMIAMSAHEQAETLTKLMEMFSDQVLMKELDECDNIETFKNILQRK- -> --MYFNSEIAEFQVEVRDRNEAFQRLTKELREKQFITDSFLQHIIEREERFPTGLPIGVAIPHTDS---EYVKKSQIAFMSLKEPITFFEMGTVDVQMIFMLALKEHEQLEMLQKLIGMIQQPEIMEKLYHCQTKSEFIEIIHHV- -> --DYFKEENVFLKFEAENRDEFFSKIGEILLEKKYVKEDFVDSIKEREKNYPTGLNYNIAIPHTNP---EFVNEEGIVTVRLKNPVIFRDMGMLEVLLVFVLLIKKEEQVNTLMKLMSLLEKKDIYEKLIKAEEKDDILKILKKN- -> --SLIQVDRIQVSCLVKDQFDAIALAAKPLLEKGCITEEFIDAAIERERIFPTGLPIGVALPHTEA---KYVLKESISILTLKNTIVFAGMGNIPVQIVFLLAISNEKQLRILQTIITIIQNEKMLKKIRDAKEPRDIYNLINTF- -> ---MFKEELIFLDHNFDSSDEVIKYSFKQLRRLDYVKEEYLDSILARESEFPTGLMINIAIPHTDS---DLAIKEAIVFIRNKKDVVFQHMIDVPTKLIFNIVVKDKNQVSFLTKLMKMFQNEILLEFLLTETDKEKIIQTLKNF- -> --REIDKDLIFINMNFENKSELFGFIADELKKRNYVTDTYEEAVNKREEKFPTGFQINIAMPHADP---VNSRADKLVVLTLEKPVEFQ--NEIGVNIVFGLVFHNDKHIDYLMRLSNLIQDSGKLEKIKKSVTKDEIYDLLDET- -> --MLFPECTLIH---ADRKEDVIWKLYEKLLQNGKVKENFYEAVLEREREYPTGLKWEVAIPHVSP---EYVLESTIAIAVLDEPVEFKRMDDVHVNVVFNIALGKGKQIEILQDIMAIFADSEKMERIVKAESPEQVISIIKG-- -> --MLLEKDLIFTEQNFNNRMEIFKFLNENLINLGYVKDSFLKGLVDREKNYPTGLKCGIAIPHTDS---IHIKEEKLSILTLKNSVSFENMDGVDVKIVIMMLIKGNNQIEMLQKLFTLFTDSKKIEYLKNLVSEEEIIDFFNKE- -> --MIIDDNLIFSNLECENSNEVLRFLSDNLEKNGYVKSSFYDGLLEREAAYPTGLDYSIAMPHTEV---EHVVKSTLSIATLKKKVDFKCAEDTPVEVVCVIAFGEEDKIDVLTKLISFFGDKEEFYKMLAS-DKDNLIKIVKKH- -> ---MIQKDLIYIHLKADTKEEIITRLADKLLEAGKVKDSFKTAVLKREVEYPTGLPYNMAMPHTFA---AHVIEPTIAVAKLDEPVLFTEMGTLPVSLVMMMAISDREQVGMLKKILRIFSEEAALEALMKSEDVDEMYKTLRYI- -> ---MIDKKYIVKNLEVNSQKELLERLGKQLVEDRIVKEGFTEALLEREREFPTGLPPGVAIPHTNG---SLVNEDRLLFATLKNPIKFNEMGAVDVQVVILLAIADQNHIQTLQKLIGSIQKEGFIKGLVDSKDTEEMESIIRQY- -> --LNLYPEDILLRIDADSCEEVLHLASSHLLGEGKVKQSYEEHLLAREEDYPTGLAINVAIPHTDY---QYANTTQLLVATLAKPVMWHNMEDIPVSVVVLSVFDKEHQLEALQQIMGVLQKQELVAQIVDADSAQQVIELFN--- -> ---MLTQELIFLQREEKTSFEFLSNISDKLLSMGYIKESFKKAILKREEIFPTGIGYSIAIPHTDS---EHIIKPGIAFVRFNNKCAFKEMCTLDVTMAFVLLVKAEEQAVLLSKLMGLFTDNELLDKLNSENDCETIVNILNDK- -> --SLLHTDLIILDAEVASAEEAIRLMGDRLEKLGFVTEGYADMVCDREKTYPTGLSWAIALPHTDP---TLVIRPAVGVIVPREPVEFKMMGALDVRLIMPLVIKDNSQLSLLKTMMGVIADAQLLERIRRSRDPREIIELLRP-- -> --IFSKNDIHGLISEETDRDQLIHLLAAEMAKYGMVEPCYGASVLEREKEFPTGVPVPIAIPHSER---SQVYKPGIGVAVLRNSVKFSSMEDLDVRVVFMLAASLDEHLHMIKDVMEIIQDSEVVNALLAAETTKEIEAIMHQ-- -> --LVFDQDLIQLHARYDSREELIKSFGKKIEEKNYAKKGYTESLLQREIEYPTGITIGIAIPHTNK---EFVNETAIAVAVLDNSIEFEDMGGVNAEIVMVLVVKNKMHISFLKNLTSLFQEEKFVKRFQNATNPAEIEEILLK-- -> --FQFIPQLIETDVCVKDKEEVIRHLADKLKAHGCSDAAYADKVLLREQEYPTGLCAAIAIPHAFD---PAISGNHVALAILQHPIRFCNMEDIDVDMVFLMAISSHEQLGMLQTIMRMLGDDTLFTRLVRLHDADEVCRQLNA-- -> --NLVERNCILLDQEIHSFEEVIQLIGKEFESAQIVKPSYVEAVIEREKVFPTGLGHTIAIPHTDP---EHVLRPGMGVVVTKEPIEVSMMGSLQSNIFFPLAMEHKKQLDLLRQLMSIFKTKEDLDTIRAAKTPDDVLAVTSK-- -> --LLIDSQLIVREKNFPDCEAAIRYGGSILYRLGYVKDTYTDSVLAREKLFPTGLPVPIAIPHTGS---EHVNRSMFCMIVFDNPVMFRQMGSIPAEIMLLLAIDGERHLEFLSDILGIFSDGSVLTRIRAAGSAEEICSILGE-- -> --TLFDSDLTFWGWSCTTPNELFARLADELEVRDLVAPTWRGAVATREEVYPTGLSCGIALPHADA---EHIIRPFIALVRPASPIPFEPMGGVDAELVMALGFTHEDQIGALQHVMEVFANERTGEALRAATSPAELIALLRG-- -> --GTLTEDLALVHPEVTGTEDLLRLMAEQARRAGRVHDTFADAVVARERRFPTGL-VPAAIPHTDA---GHVAEAGVVVALLARPVEFTEMGSVPAELAVMLLVKDEEQVTALGEVIAVLQDPALAERLAGVRDPADLVAALRP-- -> --MLLKEELVRVGLDAHDGEEALRKVAQGFVDAGYAKDSYPQAIVDREAVFPTALAFDIAIPHCDP---AHINEPAVSIVTLREPVELKMMGDLRPRVLFMLALE-HGQVEMLRRLMEVIQDQRLLEAIGACANAHELYVLMAE-- -> --KMFFPELVDVYEGTGTFDALIDYTAKKLAELGFIETTYQEALKEREKEYPTGLQFAVAIPHTDP---SHIKKPFIYILKLGESVTFGQMGTVNARYAFFLGFNKEDQLQLLQNLMAMFMDQDIMRQLEEESSESEILKIVTQF- -> --ELFNKDLILTNLHCSSKDDFFEKVSNYLMEKGYVKENFKKAIMEREQKYPTGLRFHVAIPHTDP---ENILTPFIMVVRPDQEIEFVEMGTVKARFIFVLGLNKEAQAPLLEKLIEMFMNSEAMNRIVNENDENKIMDILKKN- -> --LFFKQDLIFRDVDWKDSTELFDKISTILEDKGYVYSTFHKAIKEREKIYPTGIQIGVAIPHTDP---KNIKQAFISMVRPKKPIGFSPMGGIQAKLIFVLGVKRGLQVKVLQKLMEIFSNGDIINIMLHAQSDRELYEIMKNS- -> --DILREDLVDLSVEAASCTDLFMRISDVLFSKGYVVQEYGQQLQKREHAFPTGLAVDVAIPHTDA---VFVKEPFVYVLKPKTKIAFHQMGTVHPKLIFILGFSKDMQLALLQTLMKIFNDETMMDQLIEAETEKELFELLRKQ- -> --ELFDESLIELNGNFSSQAAFFKAVSLKLQNLQYVKNGFFEKIQEREKKFPTGLKFNVAIPHTDP---EYVNRSFIYVIRMRNSLPFCQMGTVYPKLIFLLGVTKELQLSILQSLMKLFSHEEQMTNLLEFEEAKDFVQRIREF- -> --DLFQKELTLINSSYESQAELFECTSNILEKEQYVEATFREAVTNREVIFPTGLEIKIAIPHTDT---IYVKRPFVLVNKLSTPIPFIQMGSIDVEVIFMLGIKNKDQVPLLSSIMEKFMEADFVEQIKEINDSSALCDFLKKQ- -> --RLLKKEMMYPEIHFTSQEQLFEFVGNELGRAGYVTPTYKEKISEREKSFPTGLRVDVAIPHTDP---ETVKRAFIMVMKLTEGIPFNQMGTVYPKLVFVLGFDHDIQLELLQGLMTLFNNQLAMKKLLEATCAEQLLNILEQE- -> --AIIDPSLIFTDINLTTQTDLFRFMADVLQQKKYIEKPFLKAVIQREAQFPTGMQCGVAIPHTDP---QFIKRSFIFFVRPQQPLLFHKMEDLNVSFVLLLGLDNGNHLKILQRLMTMFQKQTLIQQLLSSANNAAICDLLKNN- -> --ELMQEELIDLSCGITSKRKFFKTKVEVLKGLKLVEETYLKSVIEREKEYPTGLKVSVAIPHTSI---NHIKKPFIYFNRLMKKIEFIQMGTVKPDYILMLGIKEREQVNLLAEIINLFNQKEFVTSIRNAKSKKEIMELFDVK- -> --EMLKPDLVFLNVDEKDRKGLYKNIASKLLKLGYVKESYEEALNKREDEFPTGVVISIALPHANP---ENINKPFVCVVTTKTPIEILQMGYENADTFFFLGIQHNDQLTLLQKFMALIQNKDFVDDFQSISDESEMYQYIQNE- -> --SLFDETLITLDASYSSQEDLFKNAAEHLVDLGYIEETYLEALVNREREFPTGLECNIAIPHTDA---PHIKHPFIYLIRLNENLKFKNMGDVAVKIVLFLGIKNKKQISLLSDLMGKFEDEDISKMILNGKNEKELEQNLKKL- -> --SLFSEELITLDASYSSQEDLFRSAAKHLVDLGYIEETYLNALMTREKDFPTGLECNIAIPHTDA---PHIKHPFIYLVRLNENLQFKNMGDVAVKIVMFLGIKNKKQISLLSDLMEKFQEEKISRIILNGHDAKELETNLKEI- -> ---MFSSETIELDVMTASQDDLFRLIAEKLQGLGYVNSDYLEALTKRESVFPTGINCGLAIPHTES---DYIEKQGIAFVRLKETIRFKEMVSVDVKMLFFLLVKNAEQVKFLSDLMGKFSDDAFLTALLVGKDESAILETLNER- -> --DLIQIKDVDVNVVANDKYDLFQKISQSVALKVNVSSIIYDLLKERELLGSTAIGNGFALPHLKL---KDVKS-YIGVFVLKAPIDFDSIDDITVSVIFVVLSPSSLQLKTLTFLAKILKKSNVEHFLN--KSPQEIKDYLKTL- -> --RITFINTVKLNINCKEKFECLKKMAEYLAKENNLSEDVFSLLMAREKFGSTAVGGYFALPHAKM---DSLSKLICGIFTTEEPIDFGSLDGVPSQIFLVVLAPSSILLKALAKAAKIFKDNQLKERIISEKDKEKVIEFIKNK- -> --DLLLENCFFTDVNVKDKWQFFKEISACIAKEVGLPEKIEEALVEREKLGTTAVGGGIAIPHSRV---EGLEKIVIAAAISRKGLDFEALDKKPVYLIFVVLAPESLYLKTLAQLARILKQEQVKKRLLEAKDIQEFKKVLAEI- -> --RNLSKEVIFLDLMTKGKRSALSKIAVKIAQRGLDDRAVFRRLWKRESSGATGIGHGIAVPHAVF---QSISCPVASFTRLATPIHFGSPDGDPVDLVFTLLWPRATFLPALAQLCRVVRAPRIRKGLRLARSSDEVMAILDGD- -> --EVLAEDGIDLNFVAKEKHSALAKLAAMLATQGIDDKIIRRELLARERLGATGVGWGIAIPHALM---DELTKPVACMARLKEPIDFSAIDDAPVDILFGLLWPRGTFLPALSYLARTFRNQTTRHLIRQATTPAAVLSCLDHC- -> --DILTERDIVLDVLATDKAAVLARAAILLARTGADQQTIGEALVAREQTGSTGFGSGVAIPHALV---GGISAPTACLLLLGQPVAYDAIDERPVDIALGLLWPKRGFLPGLAQIARVMRSGRTRKLLRTAPTAAAALAYLDQK- -> --SNLSEDNITLDLATKGKHSALSRIAVKLARGGLDDRAILRGIWRRERVGSTAIGRGIAVPHVLL---RSISSPVASFTRLAPPIDFNSPDSDPVDLVFTLLWPRRTFLPALSRLFRTVRAPLIREGLRLAQSPEEVMAILMSE- -> --KNLSEKDVTLDLVTKGKLSALSKIAVRIARRGVDDQVVLRRLWKRESGGATGIGRGIAVPHALF---PSISCPVASFTRLAAPINFGSPDGDPVDLVFTLLWPRATFLPALAQLCRLVRAPQIHEGLRLARSSDEVMAILDND- -> --DLLNEDLLIPRLAADSKISAINELVDALHRGGIVTLSFLQSVLERENLQSTILGGDVALPHARS---RAASRLGLALATMAQPIDFPSGDDCAVQLICLIAVPADLYLSLLASLAQTLSDANLKRGLLHAATAGDMHRLLTE-- -> --GLLHPDLLVPGLEANGKIEVIKHLIDRLHEQGVIDLAFLQAVLERENLQSTVIDEMIALPHARG---RMVKRLGVAIGTRDCSIEFPSGDEHDVGIICLIAVPAGLYLKLIGVLARAFSDRAFVDTLIATQDAPQMHQLLTD-- -> --PWIDPEMMVPSLVSDDRMGAIKELVDRLHVTDRVDLSFLQAVLGREDLQSTVVEAGVAFPHARS---RSVRRMGASIGLSRAGINFGTATHQDVHLVCLLAVPTENYLPFLAALSRSFAQPAIRSQLMSCSTPEAMFHHVTN-- -> --IRIEAGLFLPALEVSSQEELFAALADALGAAGAIHNAFQRLLVEREALGTTGLGHGIAIPHARS---MVAQRTTLVVARLARGLDFQAVDGPVERVFLVVAPYGEGYLPLLGVLVAAVHHDTDRERLLAVESFDDLEKLARQ-- -> --------LDVPKGEGTSFASLTRFVASHLEADGCVTSSWGGAVLAREQLYPTGLPPPVAIPHADT---THTLKDALVVARLAEPLAFGAMGDLQVRLAVFIVAGNMAQVEVLERLLSILGDGARRERLEAGSAE-HACRSFEE-- -> --------NIFIQESFKEHESALIFLSEQLRRKGKVLDGFKEALLEREENYPTGLLDNVAIPHVDH---KYVKESEILLCTLENPIPFRRMDMVEVSIIILLAIDSDGHLEILRKIVKFVQNQEVLRKMFKEKDKDKVSEILDD-- -> --------IYVIEGNPVSWKEAIQMTADELYKNGCVEADFYQNCIKREQMYPTGLAVPVAIPHAES---CCIHKNGICLLRLATPVSFHRMDNLPVDFVLNLAVMDAVQLRALQNTINLFQDKEFQSDIRKLKLQ-QLKKVFVD-- -> --------YLAIEGEAKDWEEAISLCGQAIAKAGYADKTFMKACIEREKEYPTGLPVPVAIPHSKV---DGIKDNCVCFLRLKNPVRFYRMDSIETTAVFNLAIKDDQHLEFLQALMQAVMNKEVVENCMTKKLD-EIPEYLRE-- -> --------FLVFNGSALDNNEAIDKCVEKLVENGITDNLFSKLCIEREKEYPTGLPIPVALPHAYY---ENINKNCICVMRLNSPVKFKRMDDVDAKIVFNLAIKDNKHIKTLQYLMGLFSDGDSLKKILAMNED-NLIKYLEE-- -> --------FKAIELNERSNIEVIKQCGLELLNEGIVGNSFIESCIERENHFPTGLPPPVAIPHTFD---PSVKESSVCYARLKKPVTFKQMDTLAVEHVFCMALKDHTYIDFLQKLILNIQSQNFIVQLSKCEPE-NLVDFLRE-- -> --------IFVMDGSADSWEDAIQICTERLIEEGVVKPSFKEACLKREQAFPTGLPPGVAIPHAGN---EHVYENGICLLRLKHPVLFQRLDVVPVNFVYNLATSEEGHIDILKKLMESIHSGQILKDYMDVPLE-QLYDMVYK-- -> --------LVFLDKEYKDFEDVLSHVMKTLINENYAEKDFEEALLIREKEFPTGLQGAVAIPHGGS---QYVKQDFISMVTLKNPIFMNRMDNLAIDILFIIGFGKDTHLQCLKQLMGLIQDPKVIEDLRKGTSIMSVL------- -> -SSLLDPTRILLDVQSTKRTAALHEIAALLEPHPDVAPGFYQELLARERLDTTCLGNEIAIPHART---EHVKQIVIAVGRSTAGVHFEN-SNQNVRLLFILGTPKGDYLMLVGSLCRLVKDAPHRKALFAATTPAAFIATVQEL- -> -ADLLDEKQVILRLRSRKPANAIREIVQVLAHNGKIDETFLEQVFASERAHPSVVENGVAFPHART---DLVNQIVLGIGRSRAGIPFGQ-SGTRAHLIFVIGVPQNDYLICVGTLARLAKDEAIRSTLLHAETPREFLDALAVE- -> -SEILDPSLVVLELREGTAAEAILEIAELLRDHGRVQFKFADAVMEREGRTSTNTGEGVAFPHART---DLVDRLILGIGRTTPGIRFGP-TKELVHLIFLFGVPKTNYLVCVGGVARVVKDKTKRDALLAASTADEIVEQLRTG- -> -ADLLTEQQVILRLSSRKPANAIREIVNVLASGRKIAEVFLEQVLARERTHPSIVENGVVFPHART---DLVDEIVIGVGRSRAGIRFGE-NQHRANLIFVIGVPESDYLVCVGTIARLAKDDAIRSRLLNVETAREFVDALTAD- -> -SDFFKKDFCSLDLKAATKEGAIREIAALLSKSGKLKERFVSDLLGKWRHNPGCFDKKTAIAHSLS---ESVDGLVAGFGRSKNGIDFNAPDCEKANLVFLIGANPDIYLVMLAKLSKLLSEEFFRRELSSAVTHSEIISIIKRF- -> -ADLLRPDHIALQTRAKDPKSAIDEVAGLLKSVPAVLQALLKGVQSSAPCLPEGGGFALCIPHTRG---ECVNEMVMSVGRSEAGIVFPN-VELPVRYVFCIAVPRADYLRIVGLLARVFKDRTSEAELRAATTGTEFVDLLSRR- -> -LAPLTPERVVLPISSTRKVDAIREIACLFQSSGSVTRRFLSALLQQEQRFGSGVEKGVALSHYRD---ETIVDPVIGLGISKQGIDWGD--GSVVNILVLIGWPDKVYLQTVAQLASALHQNSIRSKVLEATDTDTIVKAIKSS- -> -TDVLTQDRVLFNLTANDRFEAITKVAQLLSNSPKIQAAFLDALLEAERAGLTWFEQEVAFPHIRS---ELVKELILAAGFFSPGVFFRE-NAPLVQLIFVIGAPKTTDIVVVGSLARIVSKNK--NRLLNAKNAQKFISLLSEY- -> ----------MLDLTASSREATLRALHARLCSTDAVSDRFLLDLLERAMVAPVCISADVATPHART---TAVERIVLGVARTAPGVGFDG-EHPAVRLIFMIGTPKTEYLELVATISRVLKVAGAREALLEAESEAKFRAALSRA- -> ---------------------LLSEIAKLAAGAPQLEETILTSLKEREKLVSTGLEKGIAIPHCSF---EGVEDFAVGLIVIPEGIEFEALDGKPSKLVFFIVGPSNRHIKILSSISQLAKDQGLNRRLVSAGTPDEIVGILEE-- -> ---------------------VLKIIAHIAKKNPILEKQIYKSLQEREELGSTGFSNQIAIPHCAL---EGISDFVLGILIVSEGVEFDSLDKQKTKIFVYIIAPASQHLRILSTISNYLRNQDNINKLLLAKSPSAIRETFLR-- -> ---------------------LLAEISSLAADMAGLRDRIAAVLKEREELATTALGSGTAIPHCRM---PGLNNFITGVVTTKKPIDYGAADGKKVDIFPFVIAPEKEHLKILSGMARILRNPDTRKAIRSINDSEELYNFLSD-- -> ---------------------ALEEVSRLACQVPELQEKILSALLTREETGSTGFQKGIAIPHCLI---EGISSFTVGLITIPGGMDFDSMDGLPTRVMAFIIGPTTDHIHILAGISRVLSTLENPDEIALCDSPMRVSEIMTS-- -> ---------------------VLHKIADMAASCPGLPDILYDKLSEREDLLSTGIGNGIALPHCTL---DDLEDFVIGILVVPSGVNFKAIDKKKVKLFIFIFAPKNDHISYLARISQILQSPENVEEIVSQTDPEKVYEIFSK-- -> ---------------------LLRKIAALSGNTEELEEEIYQKLKKREEQGSTAFGSGIAVPHCSF---KGLESFVLGLLILKKGTSFDAPDKKPVNLCFFIIGPENEHIQILSGITRLLNTTEAAKQLRQARWPDDAYSILVG-- -> ---------------------VMREVARLAKQCRVLEQEILVGLQAREAVGSTGVGKAVAIPHCRL---KSVKEFVVGLITVPSGVDFDSIDAEKVKLIVFIIAPENKHVRLLSVISQMLLAPKVPERILSEQTPEGVYETCVR-- -> ---------------------ALRIVARQAVQHPSLPDEIFEALQTREEIGTTGFGDGIALPHCRM---EGATEFVVGAISVTDGVEFDSLDGRPAKLLVFIIAPARAHVRLLSSISHTLLIPGAVDEMLACTTAKNLLDSFTR-- -> ---------------------VLENISDMVMKKIGTKHEVLRKLREREEIGTTGFGNHIAIPHCAL---SNIDDFVIGMLVYNDGADFDSMDEKPVKLAVFIIAPENQHIRFLSEVSGVLRQPGALEDISAQINSVAVRERFLK-- -> ---------------------VLKEITELAKENQQLADEIFKALEDREKAGTTGFGDGIAIPHCSF---EDIDHFVVGMMTFAGGVAFESVDRKPVFALFFIIGPSNRHIQILSSISKILLEKSTLASIRKAKSVEEIVEIIRG-- -> ---------------------VIREISEIAKASNLLVDDIYKAFMERENLGSTGFGDRIGIPHCRL---KNMESFVVGAVIDKEGVDFESMDGSKTNVFFFMIGPDSQHIKILSEISKILKEEGAVDKLLDSKTSSELYSNIVS-- -> ---------------------ILETIAEVAKRSPILQERILQALVARENVGSTGFEDGIAIPHCRM---AGLNHFVAGLITTPKGVAFDAMDDRPTHFFFFVIGPDNAYVRLLSNISRVAGRADIRKKLSASTSSMGAYAILID-- -> ----LRAGKVHRDVPSNGRESTIRAIVERTVLPALAPAFVVAVMVARERTLWTAIGNGIAIPQVRQPIIA-GLPVTVSVSYLEQPLLFGAPDGKPIQVIFQIISPTGEHLRVLAHLSRALLDPGFCAVIERRGSNEDLAMAAHPL- -> ----MKRGGVLHDLKGDDMETALKSAVDHMPVLSTSKKELYRLLLERERLTSTGIGKGVAIPHPRDPLSD-MNSPIISTCFLEKPIDFGAVDDRPVFVMFIFLSQSKFHLHLLSRFSFCVRDSSFVEFLKTSPDETTFFAKIADF- -> ----LARGCVIDGISGADPASLIQNAVDAIAASGHLSARLKELLLEREALTSTGIGNGIAIPHPRAPMET-FPTTRVATVFPSRPVDFNAVDRKPVFVFFFLLSPTRQHLQLLSSLSFCVRDASFVDFLRRRPDKENLMARIREA- -> ----LGTGGIIYRLDGRTRDEVLHSLVSHLHLPEVDRDYLRQVLIAREELASTAFGGGVALPHPRSPGLLNLNQPTLTLAFLEHPVDFGALDGRPVGILFLPLAPTRTHLHLLRQVAHALHNAEVREVLHRQGNREEIFAAMEHD- -> ----MRAGGVMRGICANTLPELLCPVVGHMIPDPHQRELVLAMLLAREATGITAVGGGVLAPHVRAPLIL-ETPRIV-LVYPARPLPVPTPDNAPIEAVFVLASPTRAHLTLLALLAAALRDADFRQAVLSRASEAALLTAAAAA- -> ----LKAGGVYYDVPGGSREEVLKNVIEFLPFPAMNKSSLLEMFLARESLESTAIGNGIALPHLRSPVVLNVDAPWVSLCFLKNAVDFKALDRKTVSVLFVLVSPSKAHLLILSRLSYCLQDSGFQKYLKTKASKEQMVAEAIVV- -> ----LKIGGVYYDVNGKNREEVLKNAVDLLPLPAVDKKLILEMFLARESMESTAVGNGIALPHLRNPVILNIDKPFVALCFLKSPVDFNAFDHQPVSVLFVLVSPSKTHLLLLSRLSFCLQDAGFQRRIRAQDSKEELTAEVIVI- -> ----VRAGGVHDDVPGTDKAAVLQAVVDQLPLPSVNRGFLYQMLMAREQLGSTGFGHGIAIPHARDPVVLRVAAPAVAVSYLATPVDFDSLDGKPVHTLFTMVSPSRVHLHLLAHLATALQDVDVLAAVTARAPEPELIEALARV- -> ----LRLGGIHYGLKGTDRESALRSIVSSLRIPNVDEEFLYQLLLSREGLGSTGVGYGIAIPHPRKPIVLGRSDSSVSLCFMEHPIDFGAADKKPVDIFFLIISNTREHLHLLSMISLAIHDDSFRKLLIDRASPELLFGDLERI- -> ----MRRGGVFFSVKGRDVREVLEAACMLIPLPRIDWETLLDRLLQREELASTGIGNGIAFPHPRYPMED-PAGGMISTCFLENEVDFNAVDGSPVFILFVILCPDKTHLKLLSRLSFCLRDRGFIRFLRECGNGDDLLIRVRTM- -> ----IECGGVYWDVPGSTPSEVLEAIVDRVPMRPVPRDDLLALLRSREGVGSTSLGSGFAVPHPRYPLVH-TVPPTLAVCHLAAPIAWDPNNADMVQTVFTLIAPTRIHLRLLAKLMYALSDSAFRNVIARKASAEETITAATAI- -> ----LKNGGIYFDIPGNNVVSVLESCVKKIFQVPDFKPDLLDRLVERENAFSTGVGNGMAIPHPRQQLSY-LPDPMITVNFLADPVDYNALDGRPVSILFCILCPSQHHLHLLSVLSFCLKDADFVAFIKSRPQLDELVEQTMVL- -> ----FENGNVFHAVPSDSLETLFXEIPACMNLPGHIKDTLAEQLMQREILSPTGIGNGXAVPHPKKPLGX-LKKSMIGTFFLEKPLDFKAPDGLPVFVVFVLLSADFHHLHLLSQLARLLNNTDINDFLKNSPSLEILVEKFQKN- -> ----LLRGGVHTGVKGERRDEIFGEVLNALPLPAVDKLSLKAMLISREQVGTTGIGNGIAIPHVKHPVIF-GLDPIVGLFFLEKPVNFAAPDGERVHTLFVILSGSRGHLSLLSRLAFCLQDLSVKTALDRRASPEEILTAFQVA- -> ----MRRGGVFKDVDGGTVDEALTQAASLSPVTSDHLQAFTQQLLERERLCSTGQGKGVAIPHVRSQTGD-GAEASITTCFLKEPLDFNAIDGKPVTTLFLLISPSDVHLRLLSRLAFCLRDDSFVEFLNQRPTPEDLLGKVQEL- -> ----LSRGGALEGDTGASRDELLERMVDQAPLERADRPALLLQLLEREGLTSTGLGDGIAMPHPRTPSAS-SAEPLVMLAQPEPALDWGALDGQAVHAVFLLVNPAPVHLKVLSRLAFVLRDAGFQALLRERASFEEILTRVAQL- -> ----LRKGGIHYKVAGSTVEEILKNAVALINAPPLDKETIVWHLLKREAMMTTALGSGIAIPHPRTPLIS-ISCESVSMCFLNGPVDFKALDNMPVSVLFIVLSANPRHLQILSQISHLCRKDGFMELIKRQALREEIFDYAGKE- -> ----FSDGRVFYDVDKTSKEDIFSFVVEKMDFSSKHKAEFLKRLFEREEMSSTGIGRGIAIPHPREPMEG-VEHSIINTVFLKEPVDFESIDNQKVFVLFVIVCRNKEHLKLLSSLSYCLRHDSFIDFLRKKPDPLEIFMEIDSF- -> ----ISAGGLMRGVEGETPAGVLKNLVEGAPLAKVDRSLLLERLLEREKMTSTGMGHGIALPHPRTPSQD-AMVPTVVIGLLQQPVDWMALDGERVHTALLLLSPNKSHLQLLSRVAFILRDSSFCKALAAKEEDHSLLVRLAEL- -> ----VRMGGIHFDIPGGEVKTVLESSIGRISNIPDFRDDLLERVMERENALSTGIGNGIAIPHPREPLTY-LNQALVSICFLSTPVEYNALDRRPVSVLFFILCPSKLHLNLLSTLSFCLKNTQFIGFLKSKPEPDLLIRQIETL- -> ----LVRGGVFYRIGGTTKKEVLQNALNMVKGVDSVSAPLFQMFLAREELASTGIGDHIAIPHARGSLVG-VSHPILALSFLESPIDYGALDGKPVYALFLLISPNRTHLRILAKLSFCLQAPEFKEAVLRQSSREQLLTTLSKT- -> ----LHAGGVFYQLHASVRESAWRALLGTLKLPA-DPDFLVRVLAAQERLLSTVFGEGIAMPHVRTPLVLRVPAPMLALGFFERPLEWGA--GPPVHVLFLAICRTSEHWHVLSRLSFALRDAQFKETIIKHSECDLIFSEARRV- -> ----LELGGTHYGLVGEDRDDVLRQLPEQLKLNKISPKKLGTLLLERENQSSTALGKGVAVPHPRYPLPI-KSQSRVDVFFLPTAVEWDAPDGQPVKILFLLLSAESHHLKILSQIAGLLRQAGVEDFLHQAPAQDELLDYIQTK- -> ----IARGDLVDDLPGCDRIEALSNLLSLIELPEVTRDELLDMLLAREKLASTAAGEGVAIPHPRKPLAD-IDEPHVWVARPRDPIDWGSIDQKPVRLVLLVLSCSKGHLDMLSRIALVMRAPEVRKALEQEPDRDKLCEIIEAH- -> ----ILRGAVGSAQPTD-AAKAIGFVNQLKDLPEEARLEIIDAVMERERMASTGLGRGVALPHPRRPVER-IKEPRLSVLFLEESLDWAAIDGQPVSTVLLLLSPSPMHLELLARVSLALHDSTLVELLRSAPDAAALLERVRVI- -> ----LLEGNIHYGVPGSDKKAVMAAVADRLPLASRDKALAAQALWDREMKGSTVI-DGIAIPHARSPLIF-VDRPIVTLCFLKEAVSFKAADVAPVNIVWTLVSPTRAHLAILAKVAAALHDAELRGLLSKPAPAPDILARLRTI- -> --DLIEKGGVFYGVPGAAAADVYAFVCAHADFAEISADVFCRELISRDALMSTAVGNGIALPHPTHPLLKDASLQRIFLCFPERPLDMNAPDGRPVSSLFILLTGGRCHLDILSQLANLFQKTSVRHLLERQADKNTLLAEMRKI- -> --TLLRRGGVWYNIPGKTSADFISTLVATIKLAGIDRDDLAQASARREASSSTAMGRALAFPHPGNPMAKSADDAIVALAYPRFPVDWKAPDGAPVKAVFMIVSASPDHLATLSILAKLCGDDAFYAALLRQAPLEELVGIIGKA- -> --GLLTKGGVYYNVSGITPAEALGDMVATVSVRSIERERLLTAVLEREALMPTAAGHGIALPHPRNPLISEPSEQFVSVGFLQNPIDWQALDGKPVRTIILIVSASKLHLRTLSRLSFLCQQTSFRKLLADRSSREELMAALEEA- -> --GMVRSGGVYYHITGATAEEVFTDAVSRISLAGVSPDALLTGLMERERLMSTSIGYGVALPHPRVPLVSGTENERIYVCYLDRGVNFDAMDGMPVHVLFLILSSGESHLGILSGLSYLLQQQPFRDALRSKPDTDELTAIMENH- -> --ELCEKCETWFIADPQNMSKVITALVFAAPISSINHKVLIDALLSREEMMSTAIGNGIAIPHVRLFDSTNLKEDIVVVAYLFEPVDWKAPDGKPVHTLFFVLAADTRHLQILAEIAQLASDEDFVDFLKTMPSREALIERIRQI- -> --ILFERGEVLEDVPGNSCAKIFEYICDRIVVSGLTAHQLQKELVEREKVLSTAVGNGIAIPHPRYPLVKNSSESKIVVAYLREPMDMQAPDVRKVYVMFVILSDSQFHIKVLSALATLFKNEKFRKGIQACPSKGELLDLLRRI- -> --NLIKKGGIFYNVMGNNPKELITNSINLINTSNLSKEEIIYSLLQREDLMSTGIGKGIAIPHSRNPIIADIENECVALCFSENPIDYDAIDKIPVHSLFFVLSANKRHLEILSKIVFLCQQEQFVFILDKKPTKESILDFIEKK- -> --EYLRAGGVYRDIEGDSPFEVFKSLSEKVNLSEILPVNLYEGLCAREAVLSTAVGNGIAIPHSQQPLLKNPKDQRIFICYLKNPIDMNAMDNKKVQTLIIPLSSSQSHLQIISLLAQLLSKSDFKKALELKLGLNEIYPLIRRI- -> --ILIKKGGVFYGVEGTSPDKIFKAVTEQMDLVKSDADVIYNALCAREAIMTTAVGNGIALPHARTPVIKNEEDQRVCVVYLKEPIDMKAPDNIKVFVMFIILTQNQTHLQTLSSLVSLFKNAEFRKLLESHASEEDLLRAIERM- -> --NILSPDRIVF-INHTTKRDALVELANNLSTAPQVKDELVTEILKREELMSTAIGRGIAIPHVRL---SSVTDLVMSVGICKKDIDYQSIDEIPVRILIMIAAAYTYYLQTLSFFSSKLKEKALRDKLLDASTPEEAYALLTQ-- -> --NILSPDRVVS-LDYSTKRDVLIKMSDVLGTAPQIKSELTDEIIKREELMSTAIGCGIAIPHVRL---TSVTDLVMAVGISQKDIDFEPIDSEPVRLIFMIAAATAYYLQTLSFFSTKLKNAELRNKLLAAESPEIAYKVLTK-- -> --DILTPENILL-SDFRSKTAVLNSLISVLSETHSIEEIFSMRILEREQMLSTAIGLGIAVPHVHL---SCVNNIVMACAVNRFPIDYNCIDGEPVRIVLMIASGFRRYLSLLSSCIGMLKERNFQDLLFNASSREQVWSLLAG-- -> --NVLSPDRVVF-LDYSRKRDALVALAERLASAPQIKHELSAEILRREDLMSTAIGRGIAIPHVRL---SSVTDLVVAVGVSRCDIDFNPFDDQPVKLLFMIAAAYAYYLQTLSYFSAKLKSNELRSGILTCADPAAAYELLIA-- -> --NILSPERIVF-MNHQTKHDSLVRLAQNLATAPQVKKELEAEILKREDLMSTSIGRGLAIPHVRL---SSVTDLVMSVGISKCDIGFQPVDEIPVRILFMIAAAYSYYLKTLSFFSAKLKDASLREVLLNSESPMDAYNLLIK-- -> --DVLIPSRIVH-IDSENKRDALEEVSACLGHAPEITDELAKEIFIREELMSTGIGFNVAVPHVRL---NTITNIVMAVGISRNPIDYESLDEQPVRIICMLAARQAQYLKTLGLISNVLKNTTVRESLIETQDANSAYLVLTQ-- -> --SVMTAERVLL-LPEGNKAGVLGQLIDSLSRAPEVRAVLRNGMLERERLMSTGIGFGVGVPHVRS---DAVSDLIMAVAVCKKGIDYDSLDGAPVKIVCMLAARATEYLRMLSSISSRLKDAPVREELLSLKDPAAVITLLMD-- \ No newline at end of file diff --git a/esm/examples/1xcr_1_A.a3m b/esm/examples/1xcr_1_A.a3m deleted file mode 100644 index 4c0e1c0..0000000 --- a/esm/examples/1xcr_1_A.a3m +++ /dev/null @@ -1,1176 +0,0 @@ -> -CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD -> ---QQELATPDLEDVKKVLLKKLKSSFVEASVEVVDCPDLSVEPFNLAAKGLGGVTAVIEVGGPPYLLPNVDRQKVYNIKELASKV-LDPCFALGAGAAPWPFLGKNAEMMANVLIKVV----KNKTHVALVKDDGNDCEVRVLPDS--ETRFALMANLFFCEGVQSKVLKVHCKNRIGSENFVTCMRTALESEF-NSVLGLGGAFLIKNGKARQHVMP-DFSNSPIHSEEELNKWLNFYQMSAPLVAVGTFVSKDIELDLRVQHFHSFSNHNEGGHYHEDSTPTEVEYLGYFNLGQKIYRFDQPVNTHKFGRD -> --------------MVNILQTGLKICFETAEVNVVDCPDLTQQPFHLAAPGLCGSPRLTDVGGVPYLVPLAQKEKKYNLDTVAEQV-LPGAFILGAGAGPHAAVGTNNEMIANIRTRD--SEGDNQTRLSSILPE-DGSYCLKC-SP--TRDFNLLANLMASEGKPGKVLEVKCQTRRSPDNFVSLMRHFIHKHYGDKFIGLGGVFVIEEGKAKIHIMP-DFSKKPLDTEEDVNKWLKFFEFKAPLICCSVFVTHDPGMDLRLEHTHCFSHHGQGGHYHHDVTPKTVSYRGYFVPAEWMYRIDPPTITHNIGRD -> ---SVKLDCPKLEDVANALQKGLPQYFAETEVAVVDCPDLREEPFNLAAKGLGGKTVVIDIGGPGFLFPLHDETKIYDMKDIANTV-MKSCFIIGAGAGPWPYIGKNCEMMANILINTS--SIVQKTYIAKVN-DKEDIEVELLPNS--EMRFSLLANLFACEGTSSKVLKVFCKKRKQDENFITSISTTLEKAF-NKTLGLGGTFLLKEGKARQHCMP-EFSKVPIRSNDDLNNWLKFYEMSAPLVAVGTLLSKDIDLHVRVQHFHSFSNHGEGGHYHYDTTPETVEYLGYFNLGQTLCRIDQPEKKQYFDKN -> ---KHALDPPPLVELASVISKGLQANYKSSTVSIIPCPDLTASPFHLAAPGLSGHESIADIGGPPFLHPLPDFSKKYSLPDILSHC---KGFAIGAGAGPFHVVGQNSELAPNISVDGE---VNNLTKYAKIGK-N-EVISGPV--PEGSTDCCLMANLFISSGLPGNVLKITAKSELA-NISVDGDGEVNNAKIG-NGEVISGPV--PEGSTDCCLMANGLPGNVL-KITAKKTWSN----G----------CDSST-GLRMEHTHCFAGDGKGGHYHGDTEDTEVEYEGYFNIARIIYRIDRPGGGHE---- -> ---IYPLAPPSLEELAEVLKAPLAANYERSNVAIVQCPNLQEAPFYLASQGLSGNEKIADVGGQPNLFPRPLLGTKWNMKDIATAM----SSLIGAGAGPYHQIGQNCELVPNFSWQLE--KANNQTRFVEISPQSKAARVR----KSPSLDCALMVNLYGSSGETGPVLKITAGRRKGHKSFTGCIQKALHAQYGSQTISLGGAFLVKSGKARYHVMP-DFPSDPFKNREEVDQWLTYHDFEGPMLCLSVMHSADPENGLRIEHTHSYSLGEDGGHYHYDIEESPIEYEGYFNTAKVLYRIERPM-------- -> ---SADLFAPALDDAVAPIAAFLRDRYEHASVEVVECPNLLS--WGLAMPGLGGQPRLVDVGGVPNLLDPAHQDKSFAIGDILDCA----PCVLGAASGDAAWAKGNTELMPCASRHC-------RSKSARVGADG-RCVLDEY--D--WDRVGFLANLFVCQGVPGPVLEVRARGRRLHDNFVGNIRGALLQRFP-RAIGLGGAFTMKKGLFKAHVMP-DFKDTVMVDGPEVQEWLKYYEMGPGATFLSTMLTQD-TPNLRLEHTHFFNQAGEGGHYHYGTSLD-VDYVGYFALAERVYRMENAFDRRRCNIP -> ---KMLLHQPPLEEVSEVLRTGLAKNFSFAEVNVVDCPDLSKDPFHLADKGISGQPRIVDLGGPDYLKPFAQKKKNYDFKTVAELS-LPNCLMVGAGAGPNHKVGINCELICNVKVGA-----INKTRIAKIDET-TGSYVLEE-ET--SGEFSLMGNFLVSEGKQGKVLQIKAKNRIGIENFVSCIHKTLTAHYG-KAVGLGGTFLLQTGKANIHVMP-DFLDEPLITDEQTNAWLKFFEMDAPLIHVGEIVSADPKLHLRQEHFHCFSHHGQGGHYHYDTTPDDAAYLAYFSVAEFVYRIDLPETRNFIF-- -> -----------------------LLACENLFAHRGLFPDLSVEPFSMTSTGFGRKMVIAEVGGPGNLFPIIHKEKEFDLK-ICNSC----PFVFGPGAGPWQVVGRNCEMVADANFTKV-------TKIASIPSSG-PYKMSVI--D--APKFSLMANLAVSAEPGADVVHVKCSVRTG-DNFPETMRKGLAEQFG-KCVSVAGIFIMQKGEAKLHVMP-DFPCCPFKSTVEIDQWLRFFTMKAPLVCASVFHSYD-GHKLRMEHTHCYSSHGDAGHYHYDTTPDVVEYEGWFTAAEKIYRFDEI--------- -> -LENCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTVQRDRTYDLADLPGLMNVKDGLMIGAGAGPWQHLNTNCEMMTNLSLTLEEGNIVNGTRLATVDPAGQ---RMLHVVPPEQTRCSLLNNLLISRGQPSPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPVLFYFMCFFHCSMTRYIALLIKSSINPQIQVLGAY-----SCWTMARPGSIYS---- -> -CSEFSFHVPSLEELAGVLQKGLQDNFAEVQVSVVDCPDLTKEPFTFPVNGICGKTR----------LPLVNQKKVYDLNKIAKEIKLPGA----AGAGPFQTLGFNSEFMPVIQTESEH---VNGSYFARV----------KYSEKYHDFGCALLANLFASEGQAGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGDKPVGMGGTFVIQKGKVKSHIMPAEFSSCPLNSDEEMNKWLHFYEMKAPLVCLPVFVSRDPTLPPVPTDY-LF--PGRGQNLKEELSSKPTVAQAYN-----LGTL------------ -> -VAYKPLHVPPMEEIVKVLSNGLTTNFATVEVSVVDCPDLSKEPFTLACKGLGGKPRLIEVGGPPYLLPLVQRDKLYDMKDLGKLA--EV----GAGAGPWPYAGVNCEMMVNLEVNGG--KINNHTRISKVNMKDDSCILER----DSETRCALLANIFCSEGKPGKVIKVVCKKRIGSDDFIASIRKTLNSHYKDKAVGLGGTFLLKEGKAKQHIMP-DFSKTPINSDAEVDEWLHFYNMSAPLIAVGTLASSDPGLDLRLQHFHSFSHHGEGGHYHIDTEPEIVEYVGYFNVGEFVYRVDQPQVTHKIGRD -> -FEEKPLHVPPLTELQSVIQGALGQNFATVEVSVGACPDLKLPPYGLVESGLGGRPTLLEAGGPPFLRPLVNREKLYNVHEITRKI-QGP----GAGAGPWPIRNSNCEGIYNLSVSEDD-ILTNGSYTATVRGDQEECVLEK----NEEPRCALMMNLFLSQGLPGDVLHIKAKCRTGEKNFIDAIRQGLEEHYGNRIIGLGGLFLVKTGLVHQHVMR-DFSKTPITTPEQVKQWLKFYEMPAQLNAVGTLVTKDYGLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERIVRVDKPPHLGDRPSG -> -CVEFSFHVPSLEELAGVMQMGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSE-----------------------------------------------------------VIEVKAKRRTGPLNFVTCMRQNLEKHYGNKPVGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEKAPLVCLPVFVSRDPGFDL-RLEHTHFFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSVGRD -> -FEEKPLHVPPLPELQNVIQGALRGNFAPSWRACV----LEKIPHTEP--------------------------------------------RCALLLNLFLSQGAPGQ-----------------------------------------------------------VLKISAKQRTGEQNFIECIRKGLEDHYGDRVVGLGGIFLIKKGAVHQHVM-RDFSSTPIHTDEEVNEWLKFYDMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLSTHKVGRD -> -SDDISYKLIDPDKLAHVLEDGLKRTFVNVSVKWVECPDLTQEPFNLAAPGLCGKPALMEVGDLSYLNPNPRKDKIYHINPIL--RHCNNSFIFGTG----------------------------------------------------------------------------------------------------------------------------ISEHPND--------------------------GTLGENLRCKSTHCLSHHNAGNHYLVDDTEDRIEYLGYFSPAKNVYRIDESRFGLPNLQ- -> --KKIPLSPPTLSELAEKLQGPLSANYAHSSVTVVPCPDLRESPFLLAHEGLSGDEKIADVGGQTHLYPRPRKDKTYQLDQIAQEMEMDPAMFIGACAGSYELVGQNCEMVINNGWRGSCMCTSDNGRYVKIDPETKAVVLENA---HSKAWFGLMGNVFASRGGQGDVLKITARKRIGEGSFTECIRNALHNVYGSQIVSLGGVFAIKSGKARYHIMP-DFPPEPFRNREQFNGWLTYHDFKAPMTCMTVLHSADPKLGLRMEHTHAFSTENAGGHYHYDVEDEEIEYEGCFNTAKVLYRIDQPEHSL----- -> -VASRTLHQPPLDELMNVLAEGLTANFTEATVEMADCPNFSGWPYNFYREGLCGNPILLEVGSPAYLLPTVQRDKFYDVKSLLRQINYNY----GAGAGPWPHTGCNCELIMKLNIVND--KVSPGYRLGMGVANNGECILQRI---EDETTFALLANLYVCEGKPGKVIKVRAKKRTGKLDFISCMQKALEKHYEDKLVGLGGMFEVRNGKVKQHIMP-DFSDTPLTNEAQLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFDERLGGHYHIDTTPDTIEYEGYFNVASTLYRVDQPPNKMQFGKD -> -IDRRDLFVPPVDDVISVLNQGLGKYFKEVSVSFTECPNLTSHPFNLTSAGLSGSPS---YGGASFLEPIANKSKIYDLKDLVNVTQTK------AGAGSWRFAGTNCEERRQTMLFSATAKT-TLTKLAL-TVAG-LEQGYVVCPS--EKRFLLLFTFLKAWHVLLQVIKIKVQTRIGKEDFVTSVRNVLAAHYKDQPVGLGGVILIENAPAKHHVMP-DFSTTPLETKDQLNEWLVFKDLTPPLISVGTVISADVVSFDIKAKS------------------------------------------------ -> -CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQRKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSE-----------------------------------------------------------FMPVIQTESEHKPPVNGSDGGCLLEKYSEKRHDFECALLANLASEGQPGKPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFLPAEFLYRIDQPKESHSIGRD -> -CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKFMPVIQTESEH------KPPVNGSYFAHVNPADKYSEKRHDFECALLANLFASEGQPGK-----------------------------------------------------------VIEVKAKRRTGPLNFVTSMRQTLEKHYGNKPVGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKESHSIGRD -> -IIPIDLYVPEKTELAIVLQNELSTDFEEVTVEWVDCPDLTQEPFNLAAPGLCGDIALLDIGGISNLFPFPIKNRNIYFKNILQEL---QSLIIGGGLCTRK--HLLHELIMNASEGKV----NNKSCFAATSGILHFVLSKSLANT--NPYCNIYGNFFVSKGLREQVLKVHAKHRT--RDFIVALQHAIKRFSKSQLMGFGGTFIIKNGKTIHHVIQ-NDWKVPIKMKKRIHKCIKYWKIDSPVVAFATFVSAD-HKNIYLNRWHVHA-SNDGGGYYHETEPNNTEYLGYFSPATKLYRINPVPIFREMINF -> -TSKYTLTPPPLEDLATRLQSALAKNYGHSSVTVSQCPDLRLPPFHLATQGLSSNECIADVGGQANLFPKPRLECKYSLLKIAKAMEMGPESLVGAGAGPFHVVGQNCELAPTLSWKGSFENIENRTYVAKIAKDSGEAIVSKCP----STDCALMVNLFGSSGLPGPVLKITARGRQGSGSFPKCISTALHEAYGSQPTF-PLNHLEAETTWKT-GSP-TIPSP----------------------------------------------------------------------------------------- -> -TTTHPLSPPTLEEICSTIRPALRANYKESTIDIVTCPDLTAPPFHLASQGLSGNESIADIGGQAHLFPRPLKEKQYSLIDCAKSMGMSQQLLMGAGAAPWHVIGQNAELAPNVSWEGSMDEVRNQTFVTRVESQGGHVRCERLP----SMEFALMMNLYGCEGITGDVLRVTAKGRRGEGSFTECLRQALHAEYGERQFSAPMVCLSVLHSADP-EKL-GLRME----------------------------------------------------------------------------------------- -> -VDKRSLHRPSLEEVAKALSDGLQSNFEHVQVDVVDCPDLRQKPFMLASEGICGQPRLADIGGVPYLVPIVQTDKIYDLEKVMKQTDVPDGFAIGAGAGPYHTVGINCEMMLNMKC---GQNPENKSHYAKIGED-GSCVLGKLSGP--PCEFCLMGNFLISEGKQGKVIKVSAKKRTGQENFVTAMRNGLKAKYGTEPVGMGGAFLLAQGKAKLHIMP-KFSTAPLLTEAAMNQWLKFFEMSAPLVCLSTFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPDEVEYLGYFSVAEWLYRIDAPASTHKIGRD -> -IVRIKLNTPPLRCIVKAILPELLENFENASAEVVQCPDLTQPPFNLTSEGLNGDENVFDIGDITNLIPSIKREKLYDVKDLKQIT----DVIIGACAGPYPFFGVDGESVENVTVENG-----THVHMMKSEDVA-ECYHKSLPDD--ETRFSFMANFFTSNGFRGEVLKIVCEVRK-GLSFSTCIREALKKHFG-EIIAIGGVILIENGKVKVHVVKPSLAKKPLKSGKELNKLVHFIELSPPSVGVGCIVSHD-GLL-RLQHIHLYT-RDQGGHYHNDTEPNTIKYTGYFGVSKQFTKIDKSNEVCNNLL- -> -TVRIDLNVPTLDRIIEALLPELSNNFETVSVDAVQCPNLTCSPFNLAAEGLNGDEMVIDIGSPSFLLPLVNLNKVYDIRDFAKVT----DFVIGAGAGPWPHVGVNCEFIGNVRSVNN----NSSHLYKVDPQTG-SQVHHRLPQD--ETRFALLANFYTSRGMTGEVLKIVCETRN-GLDFVTSIRKSVGKILW-QTGRFGWSDFN---------------------------------------------------------------------------------------------------------- -> -PLMINIHKPSNEELRTVIQAALEGNFKTVVTDVRQCPDLSADPFHMTSTGFGRKLVIADVGGPGNLFPI---------------------------------VGRCCEMVADANVA---------TKIASIPPEH-PYKMSVI--D--SSKFSLMANLAISGEPGAEVIHVKCSVRTG-ENFPEAIRKGLAKHFG-KTVSIAGIFIMQKGEAKLHVMP-DFPCCPFKSEDEIDKWLQFFTMKAPLVCASAISSEW-TL------IATQTMETQASHYHYDTTPDIVEYEGWFTAAEKLYRIDEV--------- -> -IIEKSLHAPPLEEIVEVLSQKLPSNFEYVRVSAEESPDLTRSPYNLTSPGLCGDAKLVELGGPPYLVPTVRRDKLYSLTDLLRHLRRDPALLAGAGAGPWPYLGVNCEGIINVYVKD--SAVSQGSHVVSVSPVQSSFVQEKLPASE---RTALLGNYLLSNGEPGMVIKVVAKKRIGEKNFITAIREALKEHYGDKVVGLGGTFALLEGRAKHHVMP-DFSATPLCSDSDVDSWLHYFEHSAPLAHVGTLVTGDLGLDLRVQHFHGVSEHGQGGHYHYDTTPLAAHYEGYFTVAGSVIRVDAPENTHAIGRD -> ----------------TFLESGLEKNFESVLVSVVDCPDLTQKPFNLSAKGLCGSPRLADVGGPPYLLPLPQKDKLYNQAEIARQVELPGAFILGAGAGPWQVVGVNSELACTVQVAAENEPISINSHVTKVNPQNNLWVLEKL--N--STDFNLMGNFLCCEGKPGKVIEIKARKRTGDENFMSATRQALQQQYGPQPVALGGVFVIEKGKANLHVMP-DFPCAPLSSDEEVDEWLKFYEMNAPLVCVGELVSHDPGLDLRVEHFHCFSEHGEGGHYHYDTTPEEVSYLAYFNIADSIYRVDQPPVSW----- -> --VKLGLYQPEANELQSVLEKGLKNSFEEASVQIIDCPNLEKEPFNLAAKGICGRPTLIDVGGVRNLQPVPMRNKVYNLDELTQMTHNPDAFLMGAGGGPFHVTRVNCEFMANIRTSV-TGHGRNLSYIARLDSET-EYKLLQIPE---NRECGLMLNALVCEGTKGKVMYVRAKKRTRDTNFITAMRETLKVAYGNKPIGLGGVFLLQKGNAKLHIMP-DFPIYPLIDEATVNSWLKFYDMHAPLVCLSTFVTHDPEMDLRIEHTHCYSNHGQGGHYHYDTTPDTVEYMGYFVPCSTLYRIDKPPVPT----- -> -----------------PLQNGLKDCYKEVKVSITNCPDLKEAPFKLNLSGLTGQNVLCDVGSMKYLLPVPDKSKRYSFDKVAELSKVVQGQLLGAGAGPFFTHNKSCEMAANVKFSG-SKVISNSTLHGVYNETP-----EVIRAT--DNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSTYVFLREALKAAFSPNPVALGGVFVLNDSKARFHVLC-GLPDDPVDTPEKVAAFVKHFEMEPPILGVGTLVSHDPNVDLKLEHFHCYNEQTLAGHFYWDTEPENAHYHFYLVVAKNLLRIDPK--------- -> ------------------------------------------------DTGVCGKTRIAEVGGVPYLLPLINKKKXYYLNKIAKEIQLPGAFVLRAGAGPSQTLGFNSEFMPVVQTESEHKPPVNGSYFAPVNAAEGGCLLEKYSEKYHDLGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGAFVIQKGKVKTHIMLAEFSSCPLDSDA----------------------------------------------------------------------------------- -> -FEQKELFVPDTQELKEVLTLGLKKNFEEVSVDFVECPDLSKEPFNLASSGLCGNPTIIEYGGAPFLLPLVQRDKLYDLDEICQKICISEYLAVGAGAGPYVLCNTNAEGIFNLKRNA-DGSIVSKSHLALVNAEK-NCERRSIPSS--ETRSALLGNVYLSEGKGGQ-------------------------------------------------------------------------------------------------------------------------------------------------- -> -VSYYGVHEVSMEEVAKILQNGLKDCFKEVRVNVANCPDLTKAPFRLSLAGLSGQNVVCDVGSMKYLLPVADKSKKYSFDKVAE---VIQGQLLGAGAGPFFTHNKNCEMAANVN-FS-DSKVISNSTLHGVYDET-TNKPEVIRAT--DNNFALLAHLLSTEGLQGS-------------------------------------------------------------------------------------------------------------------------------------------------- -> ---------------------------------------------------------------------------------------------------------------------------IIGKSMATDHAVCGSPASERA--S--NTLISSMGQLFITEAMPGKVIEIVAHRRIGEPSIFDLIQASLYNKFSELPMALGCVFYLQNSGALANVLC-EIPQEPYHTFPCLKKYQASFNIDGPVIGVGTVLSHDPKMGFSMASFHCWNSRLLTGHFENDVCPEKATYTVYLTPAKKLYRQDKPVH------- -> ---ETDLFVPEAKGLARTLQNGLRKHFAEATVEWVDCSDLTQEPFNLAAPAF-------------------------------------------------------------------------------LDEDTGMCALESITNS--NPDYYPYGNLFISEGQPGQVLKVQAKKRIN-MGFLSALQNALYYEYSRQLVGLGGTFVMKNGRAKHHVLP-YSWNARLKAAADIHNWLHYFVLDAPLIAVGTLVSSS---------------------------------------------------------- -> -FRRFRLHRPDLVAVADCLDRACRDAFEDASVELIDCPDLSEPPFCLASRGICGGPVLSIAGGVPYLLPTPQEQRRYDLRNLLKAT----PLIIGAGAASSTRFGRNAELVANLGCRVA------DGEDDGTENLA-NCRLS--RPD--FAEAGLMVDSLCSSGQTGPVFRLRASRWRPTGRLAELLQRALAKEFSKLPVGLGGVFRLSGAAARMHVMP-DFSPTPLTCSAEVNSWLRFFNMPPPIVCCGVLISHD-HSGLRLEHYHGWNPEQCGGHYHYDASPDTAEYLGYFSLATSLLRMDPPGGVDSLTGE -> -VTKHLRDPPPLDELAAVIEKALLSNFKTASAIVAECPDLKQQPFNLAASGLSGSPRIADIGGQQHLFPRPNLNAKYSLLSLAQDM----KFLLGAGAAPFQDIGQNAELAPNLSNAPSLLTFDNGTRVIKVQRDG-TPLCDR----TSSTNCALMANLFGSDGGTGPVLKINARARKG-ENFTDCIRYGLQKVYGK-PISLGGVFLLKSGKAKFHIMP-DFPPEPFRDRRQLEEWLSYHIFQAPVVCLTVMHSSDPD-GLRMEHTHCFG-TTKGGHYHYDIQDGEVECDPSYLLKNILKDV------------ -> -ISRRELTKISFENIIEAISPELSKIFELVSVEVIQCPNLTQPPFYLAAEGLSGNETAMQFGGLPYVMPFGKKEKLYDMKDIMKIT----DFVVGAGAGPWPYANICSEFIGNLRSVNN-----RSHIYTIDPKND-QLVHEELPQN--ETRFSHMAHFFTSNGFRGEVLKIVCEKRI-DVDFVTSIRLALKKYFG-ETVVLGGVILIENGKVKVHVC-PDYSKTPLDSEKKLKDWLKIYDLPTPLVCLGYVASHD-GLMMPLQHFHVFS-HGSGGHYMNDVEPATIKYTAYFNIAKNFIRVDQPEAPFSFENF -> -QKVTVQFPARAHARVAVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNKKKVYDLNKIAKEI----PFILGAGAGPFQSLGFNSE-------FMEHKPPVNGSYFACINPEDGGCLLEEK---YHDHGCALLANLFASEGQPGKVIEVKAKRRNG-LNFVTCMRQTLEKHYG-KPVGMGGTFVIQKGKVKTHVMPREFSPCPLNSDEDVNNWLHFYEMKAPLICLPVFVSKDP--DLRLEHTHCFS-HGEGGHYHHDTTPDIVEYLGYFSPAEFLYRIDQPKETHSFGRD -> -VKKHTLYTPSLEEVAKVLNDGLKGYFKKVDVAVTDCPDLRQKPFMLASEGICGRPRLSDVGGVPYLIPMARTEKIYSINDVMKCV-LPDGFVIGAGAGPHHIVGVNCEMMHNMKC---GPNAVSNTHYAK-IED-EKCALGTLPPE--KCEFCLMANLLVSEGKPGRVLRVSAKHRIGEDNFVNSMRKILNKKYGANPVGLGGVFVIQQGKAKLHVMP-HFSETPLVTNDDVNKWLKFFNMSAPLVCLSTFLSHDPGWDLRIEHTHCFSDHGEGGHYHYDVTPTEVEYLGYFNIAEFLYRIDAPTVTHSIGR- -> -VKKHFLAAPDLHDLATVLDAGLKTHFQDVTAVVAPCPDLRAPPFHLASRGLSGNQRIADVGGPPNLHPTPKFDRKYSLLDLMSLM-MSPAFVLGAGAGPFHVLGVNTELMPNLG----AGELVNLTHFAKVDETTGKCVCDKIPSN--STDCALMANLFGSDGSPGDVIKIVAKRRIGEANFLAAIQQTLRARYG-RQVSMGGVFLIKRGKASMHVMP-DFSKTPLDM-KDSHKWLRFYEMEAPMVCLTVFHSYDPGLALRMEHTHCFSDHGEGGHYHHDTTPDDVEYEAYLNTASVLYRIDQPEVGN----- -> -LFFVTI---LNFIIFLVLHEGLSGAFSHVDVQVVDCPDLRKKPYMLSSEGLCGNPRIADVGGVEYLMPLAKKDKVYDFKDITKKI-MPNAFIIGAGAGPRPHIGINCEMMANLKL---GEGESINTHIAKLDKD-GACELVHLKD---NTQFCILGNIFISEGKPGKVLKVVAKNRKGSENFVTTMRLALAKKF-EKPVGIGGVFVIQTGKAKLHIMP-DYSETPLKSTDDVNNWLKFFNMPAPLSCLSVFVSSDPGLNLRVEHTHCFSDHGVGGHYHEDTTADCVEYEGYFNVGQILYRIDQPTYVCDFGKD -> -VKSQVLETPPLEDVAKALETGLKGCFEQASVSVVDCPDLTAEPYHLAAPGISGSTRLVDVGGVPNLMPLVDRSKVYNFKQVAKDI-LPGAFFIGAGAGSSRLAGVNCEMMPNTN-----ATQEIRSYFAKVRPE-TGDMV-LEHYE--SNEFGLLGNFLASEGKQGAVLRVEASVRTGDDNFVTCMRQSLQAAFG-KPVGLGGVFVIEAGDAKLHVMV-RGVHCAA-------------------------NGDAVGWILRVEHTHCFSQHGQGGHYHYDTTPANVKYVGYFSVAEHIYRVDAPKVTHQIGRD -> -IKEKPLFQPPLQEIVDVLSAGLTSTFETVNVSAEDSPDLTRSPYNLTSPGLTGNARLVEIGGPPYLLPLVQRDKLYDLAALAQHLQRDPALVAGAGAGPWPHIGVNCEGIINLSIRN--GTVDQGTRIVSVEPVSSRYLQRQLPSSESETRTALLGNYLLSEGKPGKVIKVVAKKRIGPSNFITAIRETLKNHYGDKIVGLGGMFLLRAGKVKFHVMP-DFSSSALCTDDDVDSWLHYFEMSAPITHVGTLVTGDHGLDLRVQHFHGFSQHGDGGHYHYDTTPEAVEYEGYFALASHIIRVDAPDQTHAVGRD -> -ITEKALYVPPLEEVVDVLARGLPDTFETVSVSVVDAPDLTQEPFSLTSPG---DVKLVEIGGPPYLVPLVKRDKIYDLHLLLQHLKRDPGFLAGAGAGPWPYLGVNCEGIINLSVRN--GSVEQGTRIVSVEPVSSGFLQQRLPNTE---RTALLGNYLLSEGKPG--------------------------------------------KAKFHVMP-DFSGTALCSDSDVDGWLHYFELSAPIVNVGTLVTGDLGLDLRVQHFHGFSAHGHGGHYHYDTTPDAAHYEGYFSLAHSVVRIDPPAETHALGRD -> -IQTKALYVPPLEEIADVLSRELRSNFETVEVSVVDCPDLTQPPFDLQAPGISGNATLVEIGGPPYLVPLVQRDKVYDLAALLRHLRRDPALLVGAGAGPWPYIGVNCEGIINLRLQD--GAVRQGTRVVSVQPVSSGYLQRRLPDGE---RTALLGNYLMSEGAAGKVVRVVAKRRVGGDNFITAIRGALRARYGERGVGLGGAFVVREGRVKHHVMP-DFSSAALCSDEDVDRWLHYFEMRAPIVHVGTLVTADLGLDLRVQHFHGFSAHGDGGHYHYDTTPDSVHYEGYFTPADTIVRVDAPRETHAFGRD -> -LHKEMLSCSRVSSYGGNQQNGESSAXLSVSRAARSFTGWTGKQFC-RSSGLCGNPRITDVGGVPYLVPLVKKNKEYNMNAVSKELELPGAFILGAAAAPSRVIGMNAELMPLVLTEAEGRPAVNCSYFASINPADGQCLQEKYADRFSDCSFGLLGNLYACEGKPGKVIEVRAKRRTGSDSLITALRTTLEAHYPGESLALGGTFLIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSSPLICQSVLVSRDPGLDLRMEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFVYRIDRPKEMHRVGQD -> -VEKFAFHIPTLEEVADVLQNGLHGNFADVQVSVVDCPDMTQEPFCFPAKGICGKPRIADVGGVPYLLPLVQKEKVYDLNIIAKNIQLPGAFFLGAGAVSSRVVGSNAEFIPIVQAEKEEKAAVNGSYLAKINPEDGTCLLQKYSSLHKDYEFGLLANLYASEGLPGKVIEVRAKKRTGEQNFISCIRKALDKHYGDRTVGMGGTFIIQKGNAKLHIMPSEFSACPLETDEKVNNWLKFFEMTAPLICQPVIVSQDPGFDLRVEHTHCFSHHGEGGHYHTDTTPETVEYLGYFVPAEFLFRIDRPKETHMVGRD -> ------------------LKSGLLKNFADVTVIETECPDLSKEPFEFPVYN---------------------------VNSVARKIGLPGAYILGAGATSHKSLGMNAD-----------------------------------------------------------KKTREQAESAGTVAVNKSVGSCLLEKYRDRNNDNNFGLLYNLACEGKTG----KSACQLNSDEDVNGWLKFYEMTAPLICQLVFVSHDPGYDLCLEHTHCYSHHVEGGHYHYDTTPNTLEYLGYFHPAEFLYRIDKPSDTHMVGRD -> ----------------------LAPYFRHLTTKVVECPNLGAKPFYLGRAGISGDATLANVGSYDYLIPCADHGKMYNFVDVARYSGISFGMVLGGGIGPFQAYQKPCEC-----------------E---------VPISERA--S--NNFFSATGQFFITEATPGKVIELKAAGRVNCHNIFDLIQKALYNKYSSSPVALGGVFFLQNSAVEVNLLN-DLPKEPYHTFPCFKEFQTTFKIEGPIIGTGTIVSHDPNQDLVTQSFYCWDTKQLTGHFENDICPDMANYTVYLYPARNILRLDKPYYR------ -> -----------------R------------------------APLVFKPARLSGQNVVCDVGSMKYLLPVIDKSKRYSFDEVAELSKIIHGQLLGAGAGPFFIHNKSCEMAANVEFSD-SKIISNSTLHGVYNETP-----EVIRAT--DNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSAYVFLREALTSAFGAKPVALGGVFALNDSKARFHVLC-GLPDHPVDTPEKVAAFVKHFEMEPPVLGVGTLVSHDPNVDLKLEHFHCYNEQTLAGHFYWDTEPEKAHYRFYLAVAKNLLRIDPR--------- -> -----------------VLERGLSMNLKKVKIEWMDCPDLRL--YGFVAPGLCGTPALLEIGSLSYFCPTPRLDKKYYFRELLSLLNLTGQFIVGAGTHIDPP-----------------------TY-----------DLAE---F--NSLCVIQGNFFLSERRPGKVLQVTAHCRTGPLNFVSAIQELFNLMRTDPLIGLGGMFMVSGSPTLHHIMP-AYSRVNLYTMKQVQQWLRYRKLIEPVTAVGTIMISDYLPYLTKSHFHSHNPRSCGGHFYTNCVNTDAFYVGYFSFAEKLYCVDPPSRRD----- -> ---NVSINTATLKDVRDVL-YNLREYFNKFEIDVGSCPPLTARPYNFDFNGLSGLNILEQNFPMEKNIPL---------------DES-------DPVRP--------------------------------------IRLHT------KYK-------FFTEDRPGMVLEMYARGRKTNQSIITLMQNILHRRFS-HKMGLGGILIVKGGQLLQYNPK--FT---CEATY------HHIKCDSEITCSGAIVNDPVGLNRYM-----HS-EHGNGFFVNDITPKETEYYGIFNVADAVCRW------------ -> ---IVHLNLPDLSEVKNVLEPALREYFNEANVSVVPCPDLRESPFHLAAPGLSGETIIMKMGGTEFWIPT------------------------------------------------------------------------H------NMD-------KSCNGDPGYVLKVNAKGRRTNVNFPTAIQTGLQRRYE-PFIGLGGTFVIKNGIVRNRLRC-PLD---LNSPS------EIHHTSTPLVAVGTILSRKTGL----HTFACNR-VDVGGHFLNDFSPLDTEYEGYFNLATKFIRV------------ -> ---TFPTNPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTTIIEFLHINDNVPWNH--KTRDIREILTSS-CRDSFIIGSSYASKPHMPRYGHLIMNATYRA-PMDLKNESR-------------------------------------------------L---IF--------------AERALGGVLKMKYGSVACNLMW-DDYQEPLLPFYEFIRRQTEIHLESDMVAVGTIVNTEPRLEQRRFAFHCFSDDGVGGQFVSDTTPDTTEYEGYFNVAENIL-------------- -> ---TFPTNPPTLSEIAEVLQNGMQPLFQQLTVDIANCPCLTKPPYNLAGVGLGGNTSIIDFVHYSEILPWYR--RRVNIQEILTSS-CPDSFVIGSSYATKPHMPHYGHLIMNATYRA-PMDLKNESR-------------------------------------------------L---IF--------------AERALGGVLKMKYGSVACNLMW-DDYQEPLLPFYEFIKRQPEIHLESDMVAVGTIINNEPGLEQRSRLCGQ---------------------------------------------- -> ---------------GQLLQNGMQPLFQQVTVDIASCPCLTKPPYNLAGVGLCGNTTIIDLVYRSEIIPWNR--RKVDIRKILRSS-CRDSFVIGSSYATKPRMPHYGHLIMNATYRA-PMDIKNESRLIFAERRNGQTTIEKLTDP--NQMKATQGIMFVSEGRAGLVIRVRAKGRKTITDIITSMQTILFERYRNENKDIGGVLKMKYGSVACNLMW-DDYQEPVLPFDEFIKRQQEIHLDSDMVAVGTIINNEPEL------------------------------------------------------- -> -TVVLRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISAS----QQLIGAGAGPFFTAGKNCEAMMGNRFNTENDVRSNNTLHGVYNKSE--DKPGVLKAT--DNNFALLGHFLATEGNPGKVLAVDVSVRAK-GSIYTFLREALTAKFGSAPVALGGAFVLDNSKGRFHVMP-DFPKKPVDSPAKISSWLKFYEMSPPVMGVGTIVSHD-VGFLSTEFVDCLLDFNNSSS-YGE--P---EFQTVLIVTPFFMRGNN---------- -> -TEKVQLHAPDLEELRGVLQTGLEDNFAEVQVNVVECPDLSKEPFQFPVKGLCGNPRITDVGGVPYLVPLVQKHKEYDMNSVSKEV----PFILGAAGAPSRIVGMNAE-------LMEGKPAVNSSYMSSINPADGQCLQEDR---FSGCSFGLLGNLYACEGKSGKVLEVRAKKRTG-HSLVTALRKTLEGHYP-KSLALGGTFIIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLICQSVLVSRDP--DLRVEHTHCFS-HGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPVDTHGVGRD -> -IVRIRLSEPPLSKIVEAVLPGLKKNFESVSVEVVPCPDLTQPPFYLATEGLSGNETVIDVGSPSYLLPSVNLDKLYDIKDFKKVI-SDPLSIVGAGAGPWPYVGVNSEFIGNVKHT------INRSHFYKINPETKGILHGNLPQN--ETRFALLANFYTSNGFSGEVLKIVCETRKGPLDFVSSIREALANYY-EETVALGGAILIENGKVKVHVMP-EFSKTPLNTETELNNWLNFFEVSTPLVGLGYLVSNDPGLDLRPQHFHLFSDHGFGGHYHYDTEPITIKYTAYLNVAKNLIRIDQPKKSLSFGKD -> -IEKGTFTNHSLEDIASALKKGLSENFKNVEVEVVDCPNLRE--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYEEISKMI----EYALGAGSGAMSCLGHCGELVINENSR---------SIIARVSPDK-KCIVEKY--S--ARKHGGLGNIYYTDGKQGKVIKIKIRGRSGDGSLPQVMRSSLKIK--NEHLSLAGVFRVLNGKIRSHVQP-DYKDIKHEYYKQMKDFLQFYEPGPKLQCYTVLWTGDPGGNLREEHTHFHSYDKDAGHYHFDVTPEEIEYEGYFNTATEVHRVNNIYKELLSKNS -> -TSEHILSPPPLEDIASILATVLQSTYTSSSATVVQCPDLRLPPFRLASAGLGGNESVADIGGQAHLFPRPVFSKKYSLLRIAELM----EMLIGAGAGPFHVLQQNSELAADLCKN-V----TNQTRFTKIDNAT-KLVTDI----CPSTDCALMMNVFGSAGDPGPVLRVTARGRRPTQSFPELVRQSLQEAYGR-QVSMGGVLVLKRGTAKFHVMP-DFPPEPFTDRGQLEQWLTYHDFAAPMVCLSVLHSCDPQ-GLRMEHTHCFSAGQQGGHYHYDLLPVEVEYEAYFNSAKVMYRIDQPDA------- -> -PNFCLMLNNSFVCLLLVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLMPLVNKKKVYDLNEIAKEI----PFILGAGAGPFQTLGFNSE-------FMEHNHPVNGSYFARINPADGKCLLEQK---YHDFGCALLANLFASEGQPGKVIEVQAKRRTG-LNFVTCMRQTLEKHYG-KPVGMGGTFIVQKGTVKAHIMPAEFSSCPLTSDEAVNKWLHFYEMKAPLVCLPVFVSKDP--DLRLEHTHFFS-HGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD -> -VEEKPLYCPSLTDAAEALKDGLSETFETVEVSVVDCPDLTQKPFSLASQGLGGSPTILEVGGVPFLMPLVDRSKVYDFKDMNKVT----NFIIGAGAGPFTYAGVNCELVANLVVRQS-----QIAKLKDESKGD-EFVTETLQDS--VSSFALLANLFVSEGKPGKVIRVHCANRK-GSDFVTAARDSLLKGFP-KAIGVGGTFLVNGSKVKQHIMA-DFTTTPLDSEEKVT-------------------------------------------------------------------------------- -> -IKTYPLNPPPLSDFASLLTINLPSHFRDVSVSVVPCPDLTLPPFHLAAAGLSGNEKIADIGGPPYLHPLPNFSKKYSFLDLARLI-----FILGAGAGPFHIVGRNSELMPNLSGR---EKVLNLTKYAKVDE-Q-GCVCGPV--PGESTDFGLMANLFCSDGDPGEVLRIVAKTRTG-ENFTEAIQKVLRAEYG-RTVSLGGVFLVKKGKAMLHVMP-DFSKEPL-EHGMMDKWLKFYEVGAP-VCLSTFHSSEIE-GLRMEHTHCFGG--KGGHYHFDT--TEVEYEAYFNTAKVICRVDQPQIWN----- -> -IKTYALTSPSLPELASLLTKSLPSHFQDVSASVVPCPDLRQSPFHLAAAGLCGDEKIADIGGPPYLHPLPDFTKKYSFPELAKVL---PDFMLGAGAGPFHVVGRNSELMPNISKV-R-----NLTKYAKVNEQG-GCTCGPVPGN--STDFALMANLFCSDGSPGDVLKIIAKTRTS-ENFTSAIQSILKREYS-RPVSLGGIFLIRKGKAMLHVMP-DFSKEPLHQD-QMKEWLKFYEVEAPLVCLSTFHSHD--GALRMEHTHCFGGEGDGGHYHFDTTPEEVEYEAYFNTAKVVYRVDQPPVEG----- -> -VKKFLLHTPKIEEVAKVLNDGLKECFAEAEVEVTDCPDLRQKPFMLASEGICGKPRLSDVGGVPYLIPLAKTEKIYSIDDIMKCV-MPDGFAIGAGAGPHHIVGVNCEMMHNIKC---GPNAVSNTHYAK-IED-GKCALGTLPPE--KCEFCLMANILVSEGKPGKVLRVSAKCRTGEDNFVNAMRKILNKKYGTDPVGVGGVFVIQQGKAKLHVMP-HFSTKPLVTEGDVNNWLKFFTMSAPLVCLSTFVSHDPGWDLRIEHTHCFSDHGEGGHYHYDVTPTEVQYLGYFSIAEFMYRIDAPSVTHNIGRD -> -VDTQQLFVPSLSEVCDTLQDGLSRNFETVKVEVVDCPDLTQSPFCLSGRGLCGSPRIADVGGPPYLLPHVDRTKLYDIANLTKLI-LPNAFVVGAGAGPFPFVGQNSELMANVVT---GKNASNGSRICKII-N-NKCELHKLPQN--ETGCALMINLFASEGLGGKVLKVSARKRKGTDNFISCIRKTLDVKYE-KSVGLGGFFRVTSGTVKCHVMP-GFCDSALETEESLNNWLHFIDMPAPMTFFSVLVSRDPGMDLRQEHSHGYG-ESYGGHYHYDVTPDEVEYEGYFNIAEILYRIDRPEHTHSFRRD -> -IKSHPLAPPPLTDLASLLTTNLKPHFRDVSASVVRCPDLRQPPFHLAASGLCGNEKIADIGGPPYLHPFPNFTKKYAFLDLTKLL-MSPGFMLGAGAGPFHVVGRNSELMPNFS----GGAVMNLTKYAKVDEQ-GGCVCGPVPGN--SADFALMANLFCCDGSPGDVLKIVARTRIGKENFTAAIQKILKAEYG-RIVSLGGVFLIRKGRAKLHVMP-DFSKEPLEQ-EKTEEWLKFYECEAPLVCLSTFHSHDPGLELRMEHTHCFSEHGDGGHYHFDTTPENVEYEAYFNTAKIIYRIDQPPVEG----- -> -VVSRDFHVPSLDEVAGVFEAGLRANFATATASVVDCPDLTQAPFHLASEGICGSPRLADVGGVPNLVPLVNRDKVYNFVDVAKQI-LPGAFFLGAGAGSSRLAGVNCEMMPNTH-----ATHTIKSYFAKVDPE-DGSMV-LNPYS--SNEFGLLGNFLASEGRPGKVIKVEAETRTGDKNFVTCMREALHAHFGAMPVAIGGSFVIEAGNAKLHVMP-DFSKTPLQSDDEVAQWLKFYECQPPLTCLSVFVSHDPGMDLRVDHTHCFSQHGQGGHYHYDVTPKAVKYTGYFVVAEKVFRVDAPKETHTIGRD -> -TTKVNLDLPPLEDVADAFRDALLTNFDQVTVDVRECPDLRGEPWLFKTVGLCGKTAIADVGGVDNLHFAVNNYNSFSLQEVARTV----DFIMGPGAGNPNNVGINSELIVNNNIS-A-------SKVVTVKE-DGSYLQEDY--V--WSDVGPLANLYLSEG-KGKVVYVRAAVRKG-MNFPSLLRKSLVDGFK-RHIAVGGVFLIKTGNIKGHVMP-DFPKRDLPDTAAVNAWLKFYEMRSPLICTTVFLNGDIGLGFRQDHTHFWSHHGDGGHYHYDVTPEQVEYEGFFHLASEAHRIEPPKVPK----- -> -TFVINTLKPSNAELRSVIENALWKNYKNVQVTLTTCPDLSKPPFRMTANGFGRNLSIAEVGGMGNLFPILHKEKDYDIKIAS---------------------------------------------KATIQHGESPYKSLTI--D--SPKFNLMANLAISEEPGAEVVHVKCSERIG-ENLPRCIRKGLAWHYG-SCVSLAGIFLLLRGEADVHIVP-DYPPASFRTMDEVESWFNMFKVKAPLVCATVFHSYD-GNNLRMEHTHCYSDHQDGGHYHIDTTPETVEYEGWFTAAEKIYRVDQI--------- -> -LE-WKNLLFTYLLWKKWLMNGLQENFADVQVSVVDCPDMTRGPFCFPVKGICGKPRIADVGGVPYLLPLVQKEK-----------------------------------------FIEEKAAINGSYLAKIHPEDGSCLLQSL---YNDCEFGLLANLYASEGLPGKVIEVRAKKRTG-QNFISCIRKALDKHYG-KTVGMGGTFIIQKGNAKLHIMPSEFSACPLETDEKVNNWLKFFEMTAPLICQPVIVSQDP--DLRVEHTHCFS-HGEGGHYHMDTTPETVEYLGYFVPAEFLFRIDRPKETHMVGRD -> -AEFSF-HVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTEEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEI----PFILGAGAGPFQTLGFNSE-------FMEHKPPVNGSYFAHVNPADGGCLLEEK---HHDFECALLANLFASEGQPGKVIEVKAKRRTG-LNFVTCMRQTLEKHYG-KPVGMGGTFIIQKGKVKSHIMVRAHV-C--------SFW----------FGLPVLVSRDPSIDLRLEHTHFFS-HGEGGHYHYDTTPDTVEYLGYFLPAEFLYRIDQPKESHSIGRD -> -------MFCNWTWIKGILWN-DSGGYRKMPSHKYQVSDFRQAPYLMTGSGIGSGLRIVEVGGIGNIYPVIKCDKFFDLKAICTKS----PFVFGPGAGPWHVIGSNCEMVADANNPVA-------SKIIKINADNKAYELSTT--N--SSYFSLMANLALSNANEADVVHIHVKKRLT-TNFPESVRRTVGAYYG-NLVSIAGIFLVKAGKIKMHVMP-NFPSPNYCWKDEVLK---YFEMSAPVICACVIHSTNNERKLRMEHTHCYSEHGDGGHYHCDLSPEIVEYEGYFAPAESVYRIDLV--------- -> ---------------------------------------------------------------------------------------MPDGFVIGAGAGPHHIVGVNCEMMHNMKCGA--NAVSNTHYAKIE---DGKCSLGSLPPE--KCEFCLMANILVSEGKPGKVLRVSAKHRTGEDNFVNAMRKILNKTYGTEPVGLGGVFIIQQGKAKLHVMP-HFSTTPLVTDKDVNDWLKFFHMRAPLVCLSTLISHDPGWDLRIEHTHCFSDHGEGGHYHYDVTPEEVEYLGYFNIAEFMYRVDAPTVTHNIGRD -> --EEKELFVPEMETLCSVIETGLKSNFSDVSVSVVDCPNLSQAPFHLASSGLGGDATLVEFGSPVYLLPLVNKSKIYDIVELLRNISSYEEFTCGAGAGPFPIFNQNCEGMLNIRVGS-DGTLKNETHVARIVPG--GVELSKVPDQ--ETRCALLGNLYLSEGKAGKVLKVTAKRRTGSENFISSMRLALAEYFTDKTVGLGGTFLIKEGKAKQHVMD-EFSKVPLYTEDDVNKWLTFHEMSAPLIAVGTFVTNEADLDLRLQHFHSFSKHGEGGHYHYDVTPDTVEYEGYFAVGRRIIRIDKPEQKLK---- -> ---QHVRQPPALEELAAIIQQSLQSNFETASASVVQCPDLRQPPFKLAAPGLCGEACIGDVGARGNLFPRPNLNAKYSLLSLAEDMKMSTEFLIGAGAAPFQDIGQNAELAVNLSWQGSSLVVENKTHVVRISQDS-TSTCKTT--T--STNCALMMNLFGCHGEAGPVLKVTARSRRGKDNFTNCIRHGLYAAYGTRPVSLGGVFLLKSGKAKFHIMP-DFPPEPFPDREYMQRWITYHVFKAPIVCLTVLHSADPGLGLRMEHTHCFEGHRQGGHYHHDINDGEVEYEAYLNAASLLYRIQ----------- -> -TEKVQLHAPALEELRGVLQAGLETNFAEVQVSVVECPDLTTEPFLFPVKGLCGNPRITDVGGVPYLIPLPQKHKEYNMNIISKELELPGAFILGAAAAPSRIIGMNAELMPLVLTEAEGRPAVNGSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGKPGKVIEVRAKKRTGSNSLVTALRKTLEAQYPEKSLALGGTFVIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLVCQSVLVSRDPEDNTRPSLIRCTKDHGSA--------------------------------------- -> --QKYPLSPPSLSALAAVLQPALSRNYAHCSVSVSPCPDLRQPPFHLAAQGLSGDEKIAEVGGQSNLFPSPDLSAVWSLPEIARDAGMDAAMLLGAGAGPYRDVGQNSEWAPCYSWED--NKVRNESRCALVRKDTGKVEVRKQ--D--SLGCALMCNLFGSRGEPGDVLRITARRRTGDASFTECVQAALREAYGSTVVSLGGVVLIKKGLAKYHVMP-DFPDEPFRDLDQLMKWLTWHEYRGPIVGLTVLHSADPGGGLRLEHTHTFSAEDAGGHYHYDIEDEDVEYEAYFNTAKSPIHW------------ -> -----------LYDVCSTLECYLTPYFGHLTAKVVECPNLNQRPFYLGRSGICGDSTIANVGSLDYLLPCADPSRLYDIMDITKYTGHCQGMILGGGVGPFQCYKKPCEVSTEITYST-RGLQCNRSLIGFCSKECGSPSSERA--S--NTLLSSLGQIFITEAMPGKVVEIVAHKRIGGPSIIDLMQAALYDKFSELPMALGGVFYLQNSGAQASVLC-ELPQEPYHTFPCLKKYQTSFNIDGPIIGVGTVLSHDPKMGFSMASFYCWNSRLLTGHFENDICPEKATYTVYLTPAKKLYRQDKPVHN------ -> --AKIVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADADFTTD-HQNNVATKVSRVVPNGKGYEMSTI--D--NADFVLMANLAISDGFAGKVLRVHAAKRNGEMNYPGAIRKALIGYYDGMAEVFRN-----ESAISMCIGI-AFE------------------------------------------------------------------------------------------- -> ------------------LTGFMSGCFSKVACQVVDCPNLKDPAYALNSAGLCGSETLCDIGSFDYLLPVPNKEKRYDLLDAFSLSHVGSGFIMGAAAGPHFVAGINSELVANLSATD-GKVLQNGSYCGSYDAKN-NLPVSTL---SETSLFAMVGQMFLCEGKPGKVIQLTVSGRTREGKFDALLREALASKYGDRPVGVGGVVVQETGKCLFHVLP-EFCEEPLDTPEKLKQWLKFFEMEAPVVAVGTALSHDPKWKIRLEHFHCFNDRTKSGHCHFDSDGPTASYTAYLVPGKRLLRVDPPK-------- -> ----------------------IKDHFKSVNVRIVPCPDLKASPFRLLCSGLSGQNIVCDVGGMSYLLPVPDKTKMAANVRFEDSK-ISSNSTLHG------VYDES--T-----------------R---------SPQVLAA--T--DNNFALLAHLLATEGLPGDVIEVDASGRLKEGAPYVFLREALTSAYGDKPVALGGVFMLTGSKGRFHLQP-DFPDHPVDSPSRVAEFLKFFEMEPPVMGMGTLVSHDPGIDLKLDHFHCYNERDLAGHFYWDTEPQTAHYKFYLTVAKSLLRIDPKPK------- -> ----------------AVLQKGLKTNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLINR---------------------------------------------------------------------------------------------EKVIEVKAKRRTGQLNFVTCMRQTLGNHYGDKPVGMGGTFIVQKGKVKTHIMG---------------------------------------FDLRLEHTHFFSHHGEGGHYHYDTTPETVEYLGYFLPAELLYRIDQPKETHLIGRD -> ---IIETHKPSNGELLSVIEEALQANFKVVETKLCQCPDLASEPYNMTSSGFGRKLVIAEIGGPGNLFPVIHREKEFDLKEICDNCEAPSSFVFGPGAGPWKVVGRNCEMVADANFSSS----KVATKIASIPPNHTAYKMEVI--D--SRKFSLMANLAISAPGPAEVVYCKASVRTGKDNFPEVIRKGLAQHYGKKCVSVAGIFVMLKGKAKLHVMP-DFPGCNFKSTEEVIEWSIAMEMQ---VCFSALLVKA---------------------------------------------------------- -> --------------------------------------DLSVEPCSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDLKEICKACQSPFSFVFGPGAGPWKVVGRNCEMVSDANLTTA----KVATKIASLPPGHPPYKMDVI--D--SPKFNLMANLAMSEPGSGEVVHCKYSVRIGKDNFPETIRKALVKHYGES----------------------------------------------------------------------------LGHYYYDTTPDTVAYEGWFTAAEKIYRIDE---------- -> ----------------------------------------------MSSNGFGKNISIAEVGGMGNLFPRLHKEKEYDIKEICELCDKKSAFVFGPGACPKSVMGTTGELVADV-----------ASKVTNLVNNHSPYKTCEI--D--SPKFNLMANLAISQPEPAEVGNLTV--RVDGSDVPEKL-----------WPE----------------------------------------------------------------------GNLERHYYNDVSPKTVTYEGWFAAAERIYRIDE---------- -> ----INTLKPSNAELRSVIETALWKNFKNVQVTLATCPDLSKPPFRMTANGFGRKLSIAEVGGMGNLFPILHKDKDYDIKYVVNLCGKKSAFVFGPCACPASVIGTTGALVADVNFTSS-----QIASKATIQQKGHTSPHKSLIIE--SPKFNLMANLAISEE-PG--------------------------------------------------------------PAEVEKWLHRFKVKAPLVCATVFHSYDPEFNLRMEHTHCYSDHDDG--------------------------------------- -> ----IKTFKPSNSELCSVLGAALKKSFKKVHVELTKCPDLTAAPFHMTGTGFGRNMVIAEVGGLGNLYPGFHKEKHYDLKVAE----------------------------------------------------NKSVPFETKTIN--STKFTLTGNFIVTAE-PGPAEVVHIKCSERTGKLCFPDTLRESLEQRYGECVVLGGLFRLLRGKARVHIAPEFPEKPWKSMDEVEHWYQPFVVSAPLLCASVMHSYDPGFKLRMQHTHCISDHNDA--------------------------------------- -> ----INTLKPSNHELRSVIEAALWKNFKNVQVEVEKCPDLTAAPFHMTSPGFGRNLVIAEVGGWGNLFPNLHKEKLYDIKEICNTCGAPKAFVFGPGGCPPSAVGVNGELVADANLSEN-----KVSSKVTIQLDHYTSPYKTLFVN--STKFVLMGNLAITPE-PG--------------------------------------------------------------PAEVGKCQKLPEFREIL-------------------------------------------------------------------- -> -----NTLRPSNAELRSVIENALWKNYKNVQVTLTTCP----------------------------------------------------AFAFGPCACPASVAGTAGELVADANFAES----KIASKATIQQGGH-TSPYKSLTID--SPKFNLMANLAISEEGPAEVVHIKCSERIGEENLPGCIRKGLARHYGQSCVSLAGIFLLLRGEADVHIVP-DYPPASFKTMDEVEKWLQRFEVKAPLVCATVFHSYDPGFNLRMEHTHCYSDHDDG--------------------------------------- -> ---EIPLLTPTISEIAEVLHNEMQPLFHEVNVDIASCPCLTVAPYNLAGVGLCGNTSVIMYYPE-NSEGWNH--RTKNIRDMLTAS-CRDSFVIGATYATKPSMPYYGHLIMNATYRA-PNGIRNESRIISA------------------------------------------------------------------NKALGGVLRIKNGRVACNVMW-DDYEEPMPRFYDFIQQQQEIDVESDMVAVGTMLSEKPELEQRRSEFHCFSNIETGGQFISDTTPDTTEYEGYFNVAEQIN-------------- -> ---IHPLTPLNLSEIAEVLQNGMQSLFHDVRVDITRCPYLTTAPYNLAGVGLCGNTAVVEFLRHDQNVPWNR--RTKDIQQLLTCS-IRDSFIIGSTYATKPNMPYYGHLIMNATYKA-PMGIRNESRLIFA------------------------------------------------------------------ELALGGVLKMTNGSVACNLMW-DEYQEPISPFPDFVREQQEICLESDMVAVGTILNNEPKLEQRSQL--CGD-------------------------------------------- -> ---RTSWNSATLKDVRDVL-YKLHDYFDHFEIALVACPCLKKSPYNLDFAGLSGNMYIEELKSPVNMLPNIT---------------V-------PQAGP--------------------------------------IPFRS------NRN-------FYSDGKPGMVLKIRARGRRTDHSIITLIQSILHKRFS-YKMGLGGVLLMIGGRVARHIPE-TFP---LVLSE------RYLDCNPAVSAICTIVNNPVDLDLYYYESHCFF-GNEHGLFVNDVTPKDTEYVGYFNVAEKVYRV------------ -> ---TIPANPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTSIIEYLHRNDNAPWNH--ITWDIREILTTS-CRDSFVIGSSYAAKPHMPHYGHLIMNATYRANPMDLKNESRLIFAERRNGQTTIEKLTDP--NQMKATQGIMFVSEGRAGLVIRVRAKGRKTITDIITSMQTILYERYKNENKVVDGVLKMKYGSVACNLMW-DDYQEPVLPFYEFIKRQQCIYLESDMVAVGTIINYEPKL------------------------------------------------------- -> ---VYPLVPLTLLEVVEVLQNGMQPLFHDVKVDIARCPYLTTAPYNLAGIGLGGNTSVVEFVH--DGIPWNY--KTRNIQDVLTTS-CRNSFIIGSTYATKPHMPYYGHLIMNATYRANPIDIKNESRLIFIERRNRQTKIEKLTDP--NQMIYNKGSFFVSEGREGLVIRVCAKGRKTITDIITSMQMVLYEKYCNEDKVFGGILKMTNGSVACNLLW-DHYEEPILEFHDFIRRQQCIYLESDMIAVGTIINDKPQL------------------------------------------------------- -> ---VYPLEIPTLLEIAEVLQNGMQPLFQRVNVDIASCPNLSTAPYNLAGVGLGGYTSIVELFLLEPNVPWNQ--RTRDFQEIFTTS-CRDAFVIGTSYATKPSMPYYGHLIMNATYRA-PMDIRNESRLIFAERGNGQTRIEKLTDP-NQMKYTNKGIFFVSEGRGGHVIRVRAKGRK---TINTDIITVLYEKYENDNKFVGGVLKMTNGSVACNLMW-DDYEEPLGSFDDIIRRQQCIHLESDMIAIGTIINDKPVL------------------------------------------------------- -> ---KVTTLVPPLNDFGKAIQEYMKKNFSGVFVEVVPCPD---------------------IGGNAHLCPVPRPDIYYKLE-------FSKGFMFGPGAGPCYVIGVNSEMVADASFSEAPENVA--IKVGFTS-GKKEVGCKMMITD--KPEFCILGNLAIR--------KIRAFGRLS-------------------NVA-------------------------LT--------EQYFELDSPVVCTTVIHIRDVQCNLRLDYTHCYTD-SNAGQFYGDTEPERMEYVDYFVIAEAVYRIDK---------- -> --RTIDLHVPDPTTITNVLTHALSMNFSEVAVECIDCPDLRQ--YRLVAPGLCGNPAILEIGSLSYLFPQPRLDKKYYFKNILRQLNLTSQFIIGAGNHSYPPNYDHSELYANFMFSPGSMDVQNKRITVWSTMENNNCMHE--------------------------VCKINPL---------------------CAIQGLGGIFATFHESNLYHIMP-AFSKADLYTMNQIQQWLKYSHGSDTASSVGTIMSEG---------------------------------------------------------- -> ---CFRLHRPDLAAVADCLDRACRDAFEDASVELIDCPDLSEPPFCLAGRGICG-------GGGENSGPVEQ--RRYDLRNLLKATGHLDGLIIGAGAASSTRFGRNAELVANLGPL------GNGCRVASLRADGANCRLSRP--D--FAEAGLMVDSLCSSGQTGPVLRLRASRWRPEGRLAELLQRALAKEF----------------------------------------------------------------------------------------------------------------------- -> --VEYSFHVPSLEELVVVLQKGLKGNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNKEKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNAEFMPVIQIGSEHKPAMNGSYFAHINPADGGCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGTFVIEKGKAKTHIMPAEFSSCPLNSDEEVNKWLHFYEMRAPLVCLPVFVSKDPGFDLRLEHTHCFSHHGEGGHYHQDTTPDTVEYLGYFLPAEFLYRIDQPKETHLFGRD -> --TEFSFHVPSLEELAEVLQKGLKDNFAHVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASEHHQPVNGSYFARANPADGKCLLEKYSQKYPDFGCALLANLFASEGQPGKVIEVQAKKRTGEHNFVSCMRQTLEKHYGDKPVGMGGTFLVQKGKVKAHIMPAEFSSCSLNSDEAVNQWLNFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD -> --AEFPFHVPNLQELAAVMQKGLKENFADVQVSVVDCPDLTKEPFAFPVKGICGKTRIAEVGGVPYLMPLVNKTKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQAESEHRPAVNGSYFACINPADGGCLLEKYSEKHDDFGCALLANLFASEGKPGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGDKPVGMGGTFIIQNGKIKAHIMPGEFSTCPLNSDEDVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSNHGEGGHYHYDTTPDTVEYLGYFVPAEFLYRIDQPKETHSVGRD -> -VEKFSFHVPSLEELVGVLQNGLKNNFADVQVSVVDCPDLTKEPYTYPVKGICGKPRIIEVGGVPYLLPLVNKKKVYDMNIIAKEIEFPGAFILGAGAAPFQTLGINAEFMPVVQTKSDHKPAVNGSYYAQINPEDGGCLLEKYSKKYNDFGFALLANLFASEGQSGKVIEVKAKGRTGEYNFVTCMRKTLEKHYGDKPVGMGGTFVIQNGKVKVHIMPPEFSSCPLTSDEDVNNWLHFFEIKAPLVCQPVFVSRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFLPAEVLYRIDKPKETHTFGRD -> --AEYSFHVPSLEELVGVLQKGLMDNFAEVHVSVVDCPDLTKEPFAFPVKGICGKTRIAEVGGVPYLLPLVNKKKVYDLNKIAKDIQLPGAFILGAGAGPFQTLGFNSEFMLLVQAENEHKPPVNGSYFARVNPADGGCLLKKYSEKYRDFGCALLANLFASEGQPGKVIEVKVKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGAFIIQKGKVKTHIMPAEFSSCPLNSDEDVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDIVEYLGYFLPAELLYRIDQPKETHSFGRD -> --AEFPFHVPSLEELAGVLQNGLQENFADAQVSVVDCPDLTKEPFTFPAKGICGKTRIAEVGGVPYLMPLVNKKKVYDVNKIAKEIRLPGAFILGAGAGPFQTLGFNSEFMPVIQTEGAHTPPVNGSYFARVNPADGGCLLEKYSEKHQDYGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRETLEKHYGDKPIGMGGTFLVQKGKVKAHIMPAEFSSCPLNSDEDVNKWLQFYEMQGPLVCLPVFVSKDPGFDLRLEHTHFFSHHGNGGHYHYDTTPDTVEYLGYFSPAEFLFRIDQPKETHSIGRD -> --ERFAFHVPSLEELVGVLQNGLKANFADVQVSVVDCPDLTKDPFTFPAKGICGKPRIADVGGVPYLIPLVNREKIYDMNVVAREMELPGAFILGAGAAPFRTLGVNAEFMPIIQAESEERRAVNGSYIAQINPADGGCLLEKYSEKYEDCDFGLLANLYASQGQPGKVIEVKARGRTGKHNFVTCMRETLGKHYGDKPVGMGGTFVIQKGKAKVHIMPPEFSSCPLNSDEDVNNWLKFFEVKAPLICQTVFVSRDPGFDLRVEHTHCFSHHGEGGHYHYDTTPDTAQYLGYFLPAELLYRIDRPKETHLVGRD -> --AEFPFHVPSLSELAEVLQKGLKDNFADVHVSVVDCPDLTKSPFTFPAKGICGKTRIIEVGGVPYLLPLVNKTKVYDLNKIAQEIKFPGAFILGAGAGPFQTLGFNAEFMPIVQTASEKKSPVNGSYFAQVNPADGDCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKRRTGVLNFVTCMRQALEKHYGDKPVGMGGTFLVQKGTVKAHIMPAEFPSCPLNSDDDVNKWLRFYEMQAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGKGGHYHYDTSPDTVEYLGYFSPAEFLFRIDRPKETHSIGRD -> --NEFSLHVPTLKELAGVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLMPLVNKKKVYDLNKIAQEIKLPGAFILGAGAGPFQTLGFNSEFIPVVQTESEHNPPVNRSYFAWINPVDGGCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKKRTGQLNFVTCMRQALEDHYENKPVGMGGTFLIQKGKVKAHIMSAEFSSCPLTSDEQVNEWLNFYEMKAPLICLPVFISRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHSFGRD -> --AEYSFHVPSLEELAGVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEIGGVPYLLPVVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNAEFMPIVQTESEHKSPVNGSYFARVNPADGGCLLEKYSEKYRDFGFALLANLFASEGQHGKVIEVKAKRRTGKLNFVTCMRQTLEKHYGDKAVGMGGTFIIQKGKVKTHVMPAEFSSCPLNSEEEVNKWLNFYEMKAPLICLPVFVSKDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDIVEYLGYFSPAELLYRIDPPEETHSYGRD -> --AEFSFHVPSLSELAEVMQKGLKDNFAEVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLMPLVNKKKVYDLNKIAKEIKLPGAFMLGAGAGPFQTLGFNSEFMPIVQTESEHNPPVNGSYFSYINPADGGYLLEKYNKKYHDFGCALMANLFASEGQPGKVIEVKAKRRTGQLNFVTSMRQTLGNHYGNKPVGMGGTFIVQKGKVKAHIMPTEFSSCPLNSDEEINKWLNFYEMKAPLVCLPVFVSKDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAEFLYRIDQPKETHGFGRD -> --AEYSFHVPSLQELAGVLQKGLKEDFAQVQVSVVDCPDLTKEPFTFPAKGICGKTRIAELGGVPYLLPLVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFHTLGFNSEFMPVIQTESEHKAPVNGSYFARVNPADGGCQLEKYSSKYRGFGCALLANLFASEGQPGKVIEVKAKRRTGELNFVTCMRQTIENHYGDKPVGMGGTFLVQKGKVKTHIMPAEFSSCPLNCDEDVNKWLHFYEMTAPLVCLPVFVSRDPGFDLRLEHTHLFSHHGEGGHYHYDTTPDSVEYLGYFLPAEFLYRIDQPKETHSFGRD -> -VEKFAFHVPTLEELVGVLENGLKENFADVQVSVVDCPDLTQEPFKFPAKGICGKPRIADVGGVPYLVPLVQKDKVYDLNTVAKEIQLPGAFFLGAGAVSSRIVGGNAELIPVVLAKNEGKAAVNESYVAKINPEDGGCLLEKYKSKDKDCEFGLLANLYASEGLPGKVIEVRANRRTGEQNFISCIRKTLEKYYGDKPVGMGGTFVIQKGKAKIHVMPSEFSACPLNTEEDVNHWLKFFEMKAPLVCQPVLVSQDPGFDLRVEHTHCFSHHGEGGHYHTDTTPETVEYLGYFVPAEYLFRIDRPKETHMVGRD -> -VEKFALHIPSLEEIVGVLQSGLKENYADVQVSVVDCPDLTQKPFGFPVKGICGQSRIADVGGVPYLLPLVQKDKVYDLNDIAKEIQLPGAFFLGAGAASSRIVGGNAELMPVVQAQKENKPATNGSYIARFKPKDGGYLLEKYNTKYHDCEFGLLANLYASEGLPGKVIEVKANRRTGEQNFISCIRKALEKHYGDKPVGMGGTFVMQKGKAKIHVMP-EFSTCPLNTDEEVNNWLKFFEMTAPLICQPVLVSRDPGFDLRLEHTHCFSHHGDGGHYHTDTTPETVEYLGYFAPAEYLFRIDRPKETHMVGRD -> --DRKEAFVPPLDELAAVLQAGLSTNFLDAKVKVVDCPDLTQPPFTLAAPGLCGSPRVADVGGVPYLIPTPQLDKKYNLEQVAGQVDLPGAFVLGAGAGGAHVVGVNCEMMPNIRTTGGAHSRNNQTRISRVNTEDGTCILEHYEETYQCRDFCLLANLFFSEGKPGKVLEVKAKVRTGQENFVSCMRKTLEQQYGDRPVALGGTFLLEKGQAKIHIMP-GFSQTPLQSEQDVNNWLNFFEMSGPLINLSVFVSRDPGLDLRVEHTHCFSHHGEGGHYHYDTTPEEVEYRGYFLPAEYIYRVDRPKISHMIGRD -> -VEKFDFHVPSLEEVVSVLQNGLKENFADVQVSVVDCPDLTQEPFRFPVKGICGKPRIADVGGVPYLLPLVQKDKVYDLNTVAKEIQLPGAFFLGAGAVSSRVVGGNAEFIPVVQAEKEKKAAINGSYIAKINPEDDGCLLQKYSSLYNDCEFGLLANLYASEGLPGEVIEVRANRRIGEQNFISCIRKALEKHYGDKPVGMGGTFIIQKGKAKLHIMPSEFSACPLKTDEELNNWLKFFEMKAPLICQPVIVSQDPGFDLRVEHTHCFSHHGEGGHYHMDTTPETVEYLGYFVPAEFLFRIDRPKETHMVGRD -> --VEYALYMPSLEEFVGVLQKGLEDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIVGVGGVPYLLPLVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVVQTESEHKPPVNGSYFACINPKHGGCLLQKYSEKYHDFGCALLADLFASEGQPGKVIEVKAKRRTGKLNFITCMRQTLEKHYGDKPVGMGGTFILQKGKVKTHVMPPEFSSCPLNSEEELNRWLHFFEMKAPLICQTVFVSKDPGFDLRLEHTHFFSHHGEGGHYHYDTTPEVVEYLGYLSPAEFLYRIDQPEETHSFGRD -> --ERFAFHVPSLEELAGVLQKGLKENFADAQVSVIDCPDLTKEPFNFPVKGICGKPRIADVGGVPYLIPVVQKEKVYDLNTVAKDIELPGAFILGAGAASSRILGVNAEFIPVVQTQSDKKPAVNGSYIAQINPVDKGCLLEKYSSKYTDCEFGLLANLYASEGQPGKVIEVKANGRTGELNFVSCLRQILEKHYGEKPVGMGGTFVIQKGKAKIHIMPPEFSACPLNTDEDVNNWLKFFEMKAPLVCQPVIVSRDPGFDLRTEHTHCFSAHGEGGHYHNDTTPDSVQYCGYFLPAEFLFRIDRPKETHMVGRD -> --NKVKLHTPSLRSVSEALSEGLQNNFAEVNVSVVDCPDLRKEPFMLASEGICGHPRLADVGGVPNLIPLPQKDKIYNLETIAKQVELPNAFIIGAGAGPSHFVGVNCELMPNINIGDN----QNNTHFATVAEDG-KCHLEKL-RD--STDFRLLANLFASEGQQGKVICIHVKKRTGPDNFVTAIRKILLNNYKDQPVGVGGSFLIKNGKAKIHVMP-HFSETPLKTDEDVNNWLKFYNMSAPLVCLSVFVSHDPDLDLRVEHTHCFSNHGEGGHYHTDTTPDDVEYLGYFNIAEYMFRIDPPTETHLIGRD -> -VEKFAFHVPSLEELAGVLQKGLKENFADAQVSVVDCPDLTQEPFNFPAKGICGKPRIADVGGVPYLIPLAQKEKVYDLNTVAKDIELPGAFILGAGAVSSRVVGVNAELIPIVQTKNEKKPAINGSYIAQINPADKGCLLEKYSSKYSDCEFGLLANLYASEGQPGKVIEVKANGRTGELNFVSCLRQILEKHYGEKPVGMGGTFIIQKGKAKIHVMPPEFSTCPLNTDEDVNNWLKFFEMKAPLICQPVIVSRDPGFDLRLEHTHCFSHHGEGGHYHTDTTPDAAQYRAYLAPAELLFRIDRPKDTHSVGRD -> --AEFSLHVPSLEELAEVLQKGLKENFAAAQVSVVDCPDLTKEPFAFPVKGICGKTRIAEVGGVPYLMPLVNRTKVYDLNEISRKIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTESEHSHPVNGSYFARVNPADGGCLLEKYSQRGHDFGCALLANLFASEGQPGKVIEVQVKRRTGQLNFVTCMRQTLEKHYGNKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLTSDEAVNHWLHFYEMTAPLLCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDLVEYLGYFSPAQLLYRIDQPKETHLFGRD -> -IKEKPLFQPPLQEIADVLSVGLTSTFETVSVSVADTPDLTQSPYNLITPGLTGNAKLVEIGGPPYLLPLVQRDKVYDLAALARHFNSDPALLAGAGAGPWPHIGVNCEGIINLSIHN--GSVEQGTRIVSVEPVTSGYLQRRLPNT--ETRTALLGNYLFSEGKPGKVIKVVAKKRIGPSNFITAIRETLKNHYGDKIVGLGGLFMLRAGKVKFHVMP-DFSSSALCTDADVDNWLHFFEMRAPITHVGTLVTGDHGLDLRVQHFHGFSEHGDGGHYHYDTTPDDVHYEGYFALAASIIRVDAPEETHAVGRD -> --AKHQLHCPSLEDVAKVLNDGLKNTFEHVEVSVVDCPDLKEKPFMLASEGICGKPCLADVGGVPYLVPIVQKDKIYNLEQVVKQTNVSDPLVIGAGAGPFNVVGVNSEMMHNMKYGD---KPFNNSHYAKINEDG-SYELGRFTTS--CCEFGLMANLMISEGKPGKVIRVSAKKRTGADNFVTAMRKALAAHYGTDPVGLGGAFLLAKGKAKLHVMP-KFSTAPLLTNEAMNSWLKFFEMEAPLVCLSVFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPEEVEYLGYFNVAECMFRIDAPASTHQIGRD -> --AEFSFHVPSLEELAGVLQKGLRGNFAEAQVSVVECPDLTQAPFTFPAKGICGKTRIAEVGGVPYLMPLVNLKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHRAPVNGSYFARVSPADGGCVLQKYSEKYHDFGCALLANLFASEGQPGKVIEVKAKRRTGKLNFVTCMRQTLENHYGEKPVGMGGAFLVEKGQVKAHIMPAEFSPCPLTSDEEVAEWLRFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHCDTTPDTVEYLGYFSPAEFLFRIDQPMESHSFGRD -> --VKHSLHRPDLDEVAKVLNDGLKSTFEHVEVSVVDCPNLKEKPFMLASEGICGKPRLADVGGVPYLVPIVQKDKIYSLEEIMRKTEVSDGLAIGAGAGPFNVVGVNSEMMHNTKYGE---KPFNNSHFAKINEDG-SYELGRFTTM--CCEFGLMANLHISEGKPGKVIRVSAKRRTGNDNFVTAMRKVLAAHYGSNPVGLGGAFLLAKGKAKLHIMP-KFSTAPLLTNEAMNSWLKFFEMDAPLVCLSVFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPEEVEYLGYFNVAEWMYRIDAPASTHQIGRD -> --EKSAFHVPDLEELCRVLQDGLKKNFANVQVCVVDCPDLAQEPFTFAAAGICGKPRIADVGGVPYLLPLPQTEKIYNLNVVAKEVELPGGFILGAGAASFKAMGVIAELMPNVSTKGNGKPEVNHSYSAKIDPATGGCVLERYGETYKTCDFALLANLFISEGKPGKVVQVRSSRRTGQSNFVSCMRETLEQHYGDKPVGMGGTFLIQTGKAKLHVMP-EFSTCPLNSNEAVNNWLKFFDMSAPLICQSVFVSRDLGFDLRLEHTHCFSHHGEGGHYHYDITPDNVEYLGYFVPAEYLYRIDRPEKTHKIGRD -> --ASKSLFVPPLEELVEVLGSGLVSNFETVRVEIVDCPDLTKEPFTLACKGLGGKPRLVEIGGPPYLLPLVRREKLYNMSDIGKLTDVEPTFLIGAGAGPWPYAGVNCEMMVNLEVKG--GKVNNHTRISKINIKDGSCILERLPDT--ETRCALLANIFCSEGKPGKVLQVSCKKRIGNDDFIASIRKSLQAHYKEKAVGLGGTFLLKEGKAKQHIMP-EFSVTPINTDEEVEKWLHFYNMSAPLIAVGTLASADPGLDLRLQHFHSFSHHGEGGHYHIDTEPDNVEYLGYFALGEYVYRIDQPTDTHHVGRD -> --AEYSFHVPSLEELVGVLRKGLTDNFADVQVSVVDCPNLTKEPFTFPVKGIYGKTRIAEVGGVTYLLPLINKKKVYDLNKITKEIQLPGAFVLGAGAGPFPTLGFNSEFMPVVQTESEHKPPVNGSYFAHVKSADGGCLLEKYSEKYHDLGFALLANLFASEGQPGKVMEVKCKRRPGKLNFVTCTRQTLEKHYGDKPVGMGGTFVIQKGKVKTHIMPAEFSSCPLNSDEDVNKWLRFYEMKAPLVCLPVFISRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPTETHSFGQD -> --ESCALHLPALEEIAAVLESGLKKNYEDVQVEVVDCPDLTQEPFEFPVKGLCGKSRIADVGGVPYLVPTARPDKIYDINTVAKQIDLPGAYILGAGAVSHRSVGMNAELIFSVQAESSSSPAVNGNYMASVNPADNSCLLEKYQDKHKDNAFGLLSNLYASEGKPGKVIQVKAKRRTGKENFVSCMRKSLREHYGDKAVGMGGTFVIQEGKAKLHVMPREFSACPLNTDEDVDRWLNYYEMRAPLICQSVFVSHDPGFDLRVEHTHCFSHHGEGGHYHTDTTPDTVQYLGYFHPAEYLYRIDRPAVTHMVGRD -> -IKEKPFHKPPLTEVADVLSRGLTATFEAVSVAVVECPDLTRPPFNLTTQGLCGDPKLVELGGPPYLVPLVQRDKLYDLAALTRHLHRDPANLVGAGAGPWPHIGVNCEGIIDLSVRN--GSVSQGTRIVSVEPVSSGYLQRRLPPT--ETRTALLGNYLLSEGRPGKVLKVVAKKRIGESNFITAIRETLKNHYGDKVVGLGGTFLLREGRVKYHVMP-DFSTTALCSDADVDGWLHYFEMKAPLVQLGTLVTGDLDLDLRVQHFHGWSEHGDGGHYHHDTTPAAAHYEGYFTLAGSVLRIDPPADTHGLGRD -> --KKADLHVPTLEEAAKVLEKGLKNNFENVSVSVVDCPDLTQKPFNLSSPGICGNERLADVGGPPYLVPQYNKDKIYDVGKVSEEVGLPGAFVIGAGAGPWPLVGVNSEMICNVKLGKNGQPTVNNTYIAKVGEKDGKCQQMQI-KD--STEFCLMANLLCSEGKQGKVLQVKASKRTGPENFMSSLRKTLDSHYENKSVALGGVFLVETGKATLHIMP-DFSKVPLKSDGEVDEWLQYFEMDAPLVCLGELVSRDVNLDLRTEHFHCFSDHGQGGHYHYDTTPDTVSYRGYFTIPHSVYRLDQPKSN------ -> -IEKKSLDRPPLEELAKVLNKGLQSNFEHVTVEVVDCPDLTQQPFTLAKKGLGGSPKLVEVGGVPYLLPLVKREKVYDLKKIATMIGSDPAFIIGAGAGPHPYAGVNCEGILNMNIAK--GVVDQQTRISKVNPSNEEVPIQEILPN-NETRVALLANLFFSSGEPGKVLKIHAKKRTGPLDFIASIRQTLVNEYKNKVVGLGGAFLLKEGKAKQHVMR-DFSKTPINTDEELNNWLKFYNMRAPLVAVGTLINNDHGLDLRVQHFHSFSHHGEAGHYHIDVTPETAEYLGYFNTGEEIYRVDRPVETHQFGRD -> -VEKFALHVPSLEELSGVLQNGLTENFADVQVSVVECPDLTHDPFNFPVKGICGKPRIADVGGVPYLVPLVQKDKVYDLNTVAKQIELPGAFILGAGAGSSRILGVNAEFIPVVQAESEQKPAVNASYTAQINPADGGCLLEKYSKKYSDCEFGLLANLYASQGQPGKVIEVRANGRTGQHNFVTCMRQIIEKCYGDKPVGIGGTFVIQKGKAKIHIMPPEFSACPLNTDEEVNNWLNFFEMKAPLICQPVLISRDPGFDLRVEHTHCFSHHGEGGHYHNDTTPDSVQYLGYFLPAELLFRIDRPKESHMVGRD -> --VKHNLHKPNLNEVAKVLQAGLSNTFSHISVDVVDCPDLKGKPYMLAAEGICGNPCLADVGGVPYLIPVARADKVYNLREIAKQIELPNALIIGAGAGPRHHVGTNCEMMPNIKFNEN---EFNNTHIAKIGKDG-NCELVHL-KD--SEEFCLLGNLFASEGKSGKVIKVTAQHRMTSENFVSVMRKTLAEHYKDQPVGIGGVFNIQVGKAKLHIMP-DYSKTPLKTDEDVNNWLKFYNQPAPLICLSTFISHDPGLDLRVEHTHCFSDHDVGGHYHEDTTPDIVKYEGYFNVADFIYRIDPPAETHQVGRD -> ---RRALHIPPLEEIRDILREALPANFAEVTVDVVDCPDLTQQPFTLAEAGLGGGTKLLEIGGPPYLLPLVNRDKVYDVKSICQNVNHNGKFVVGAGAGPWPLVNTNCELIMNVSISPAESSTKNATHICMVDKDNGKCIDQTLSSS--ETRFALLANLFVSEGKPGKVIKVHAKKRTGSNDFIASIRKALAARYTNQLVGLGGTFLLKEGKANQHIMP-DFSKVPLTSDDDLNKWLRFYEMSAPLVAVGTLVTAETDLDLRVQHFHSFSHHGEGGHYHYDTTPDTVEYLGYFNVGEAVYRIDKPPMAQAFGKD -> --VKKNLYVPSLDEIKDVLKEGLVKNFLDVEVEVVDCPDLTQEPFTLAAPGLCGNPTLLEIGGPSYLLPTVQKNKLYDVQQLLNHLQYKTDFVIGAGAGPWPYINSNCELIMNMTFSP---NVQNGTRISSVSKANGKCVLQNLPNS--ETRFALLANLFVTEGKPGKVLKVHVKKRTGNNDFIASMQKAIAQHYQNNLVGLGGTFLIKDGKVKQHVMP-DFSVTPLNTEAQLNKWLHFYNMSTPLIAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRVDKPLTGVQFGKD -> -ITKKQLHVPSLDEVKEVLKEGLLTNFAEFQVEVVDCPNLMQEPFTLAAPGLGGNPTLLEIGGPPFLLPMVQRNKVYDIRQLLNHLQYNKDFVVGAGAGPWPYANTNCELMMNVAISS--SNVTNGTRISSVDKTNGNCVLQTLPNE--ETRCALLANLFVSEGKPGKVLQVRAKKRTGNDDFIACMQKAIAQHYQNDLVGLGGTFLMKDGKIKQHIMP-DFSATPLNTEAQLNNWLNFFNMSTPLIAVGTFVSSESDVDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRIDQPTTKVQFGKD -> -VEKFAFHVPSLEELAGVLQKGLKENFADALVSVVDCPDLTQEPFTFPVKGICGKPRIADVGGVPHLLPLVQKDKVYDLNTVAKEIELPGAFILGAGAASSRILGVNAELIPIAQTETEQKHAVNASYTARINPTDGGCLLEKY--K--YSGFGLLANLFASQGQPGKVIEVKANGRTGQHNFITCLRHILEKHYGDKPVGMGGTFLIQKGKAKMHIMPPEFSACPLNTDEEVNNWLKFFEMKAPLVCQPVIVSRDPGFDLRLEHTHGFSHYGEGGHYHNDTTPDSVEYLGYFMPAELLFRIDRPKETHLIGRD -> ----------------EVLHKGLKSNFAEVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLMPIVNKKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFIPLVQTESENHAPVNGSYFARINPADGGCMLEKYSQKYRDFGCALLANLFASEGQPGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGNQPVGMGGTFIVQKGKVKAHIMPADFSSCPLNSDEEVNKWLSFYEMTAPLVCLPVFVSRDPGFDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQLLYRIDQPKETHLFGRD -> --ESKELLLPPLAELSQVLKDGLSKNFSNVEVNVVDCPDLREKPWTLAAPGICGRPRIADIGGPPYLIPLPDLSKLYSFDDIANSVELPGGFIIGAGAGSSKFVGVNCEMMTNLVTSS-EQKGVIATKIAKVSKEDGSCVLENY--N--CGEFSLLGNFLVSDGHPGKVLKVCASRRTGNENFITCMRHALARYYGDSPVGLGGVFVLEKGKAKIHVMP-SFSETPLKTDEDVNNWLKFYEMSAPLVCVGVFESHDPGLDLRIEHFHCFSAHGEGGHYHYDVTPDDVHYTGFFSLAERVYRIDRPLATHNVGRD -> -ITKRDLHTPSLDEIKDVLKEGLAKNFVEVQVEVVDCPDLTQQPFTLAAPGLNGNPVLLEVGGPSYLLPIVQKNKLYDIQQLLNHLQYNKDFVVGAGAGPWPHINSNCELMMNMTISP--SNVQNGTRIASVNKENGNCVLQNLPNS--ETRFALLANLFVTEGKPGKVLKVHAKKRTGNNDFIASMQKAIAQQYQNNLVGLGGTFLMKDGKVKQHVMA-DFSAIPLNTETQLNNWLNFFNMSTPLVAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRVDKPSTLLQFGKD -> ------LHVPPLQEICQVLQNGLRNHFEEVEVTSTRCPNLQKKPFLLAAEGLSGSPRLADVGGVPNLIPLVQKDKVYNFPEVAKQIDLPDAFIIGAGAGPCHYIGVNSELMPNIKNGK---SVINKTHFAKVAEDG-SCDLQLI-KD--NTEFCLMGNLFASEGKPGEVLKIFARKRIGSDNFVTAMRKILANHYKEKSVGMGGVFLINKGKAKLHVMP-DFSTKPLNTDEDVDNWLKFYNMNAPLICLSTFISFDPGLDLRVEHTHCFSEHGEGGHYHTDTTPEEAEYLAYYNIAEYIYRIDPPSQTHSVGR- -> --ESRDLLLPPLEELVQVLKAGLAKNFSNVEVEVVDCPDLRVKPWKLAAPGICGRTRIADVGGPPYLIPLPNLSKLYSFDDVASNVDLPGGFVIGAGAGSSKFVGVNCEMMANLVTNS-EQKGVIATKIAKVNEVNGACVLEEY--N--CREFGLLGNFLISDGSPGKVLKVCASKRTGDENFITCMRHTLAGHYGNRPVGVGGVFVIEKGKAKIHVMP-KFSETPLKTDTDVNNWLKFYNMSAPLVCVGVFESHDPGLDLRIEHFHCFSDHGEGGHYHYDVTPVDVQYTGFFSLAEKVYRIDRPQTTHNVGRD -> -VKKVTLQKPSLEEVAKILNDGLGKHFEHASVSVVDCPDLTQSPFHLAAPGLGGQTAIADVGGPPYLVPLVQRDKKYSFEQVASLVADKNAFLIGASAGPFHLVGQNCELMPNVLLKRVFEVVENNTHFSKVNEKD-EYSLSKI--S--ASEFGLLGNMFVSEGKPCKVLKVEARKRTGADNFVTAMRNVLREHYQQTPVSLGGSFLVATGKAKLHIMP-DFSTKPLLSDDDVNNWLRFFEMDSPLVCLSVFHSLDPQLDLRIEHTHCFSDHNQGGHYHYDTTPQDVSYLGYFNLASAIVRIDAPKETHGIGRD -> --NKIPTLVPSLDEVVSVLDDGLKKNFSNVSVSVVDCPDLTQKPFKLASPGLCGNARLADVGGPGFLLPLPQKDKKFRYSQIAESVELPGAFMIGAGAGPCHIVGVNSELIKNVKMDGAGGVTKINSHIAKVNPQDGGCILETI--D--KPEFSLMGNFLCSDGQPGKVLEVKASCRTGEENLMSCLRKALQARYGEKPVALGGVFLVEKGKANLHIMP-EFSDTVLDSQEKVNNWLKFYEMDAVLVCVGELVSHDPGYDLRVEHFHCFSDHGQGGHYHFDVTPKDVEYRGYFVLAESIYRIDQPVKTTQLGR- -> --VKKELHVPTLEEVKNVFLKALKENFKDVEISVVDCPDLTEEPFTLSAPGLGGRMNIVEVGGPPYLLPLVNREKVYDLQSLLKDLKYGDRFAAGAGAGPWPYINQNCEMMMNVMIDS--SKIKNGTRIASVKNDDQTCLLEVLKGN--ETRFALLANLFLCEGIPGRVLKVHVKTRVGKKDFIATMQQALAEHYVDNLVGLGGTFVIKQGKAKQHVMP-DFSKTPLNTVEDLDKWLHFYEMSAPLVAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLGYFNVGEVLYRVDQPPNPLQFGKD -> --ENCSFHVPSLEEICSVLKSGLLKNFADVSVIVTECPDLSKEPFEFPVKGLCGKSRIADVGGVPYLVPKPRLDKVYNVNAVAKKIGLPGAYILGAGATSHKSLGMNAELIFSVQAENESIQAVNKSYVASVNPGDGSCLLEKYRDRNNDNDFGLLSNLYACEGKPGKVIEVSVKRRIGQDNFVSCMRKSLKTHYGEKAVGLGGTFLLKEGKAKLHVMPREYSACPLNTDEDVNGWLKFYEMKAPLICQSVFVSHDPGYDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFHPAELLYRIDKPSATHMVGRD -> -VEKFSLHVVGLEELCEVLQDGLKTNFAEVQVTVVDCPDLTKEPFTFAAPGICGNPRLADVGGVPYLIPVPQTQKVYNLNAVAQDVQLPGAFIIGAGAVSSKAVGMNGEFMPNIITEKDGKPAVSHSYCATINPANGKCVLEKYTETYKTMDFEMLANLYISEGQPGKVIEVKATRRTGESDFVKCMREALGYRYGDKPVGMGGVFIIQKGKAKLHVMP-AFSSTPLESDREVTKWLKFFDMNSPLICQSTFVSHDPGLELRVEHTHCFSQHGEGGHYHYDTTPNIIQYLGYFLPAEHLYRIDRPNKSAS---- -> --EKVELHAPELEELRAVLQSGLEANFAEVQVSVVDCPDLTKEPFQFPVKGLCGNPRITDVGGVPYVVPLVKKEKEYNMNTISKELELPGAFILGAAAAPSRIVGMNAELMPLVLTEAQGRSAVNSSYFSSINPADGQCLLEKYSDKFSDCNFALLGNLYACEGKPGKVIEVRAKKRTGTHSLVTALRTTLEGHYPDKSLALGGTFIIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEFSAPLICQSVLVSRDPGLDLRMEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFMPAQFVYRIDRPKETHKFGRD -> --ESRDLLQPPLEELVQVLKHGLSQNFSNVEVEVVDCPDLREKPWTLAAPGICGRARIADVGGVPYLIPLPNLSKLYSFDDVAKNSDLPGGFVIGAGAGSSDFVGVNCEMMANLVTNS-EQKGIIATKIAKVNEENGSFVLEDY--N--CGEFNLLGNFLVSEGKPGKVLKICVSKRTGVENFVSCMRNTLAGRYGDQPVGMGGVFVIEKGKAKIHVMP-RFSKTPLNTDADVNNWLKFYEMSAPLVCVGVLESYDPGLDLRIEHFHCFSDHGEGGHYHYDVTPDDVQYTGFFNFAEKIVRIDRPLTTHNVGRD -> --VKKELHVPPLDEIKDVLKEGLARNFFDVQVEVVDCPDLTQEPFTLAAPGLGGNPTVLEIGGPSFLLPLVHRNKLYDVQQLLKHLQCCKNFVIGAGAGPWPHLNCNCELMMNMIVSP--TGVKSGTHIASVDKTNGNCVLENLPNN--ETRLAILANLYVSDGKPGQVLKVHAKKRTGNDDFIACMQKAMAQHYEKNLVGLGGTFLMKDGKIKQHVMA-DFSTTPLNTEKELNNWLHFYNMSTPLVAVGTFVSSESDVDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGSVLYRIDQPTSKLQFGKD -> --EKFELHVPKLEELCEVLQDGLKKNFADMKVSVVDCPDLSEDPFRFPVKGLCGKPRITDVGGVPYLVPLVQLDKVYNMNTVAKEVELPGAFILGAGAVSSKAVGMNAELMPLVLTESGGKPAVNSSYLSSINPGEGTCLLEKYSDKYSDCDFGLLANLYACEGKPGKVLEVKASRRTGGDSLVTCLRKTLANHYSDKSLALGGTFVIQKGKAKIHIMPREFSACPLSSDEDVNEWLKHFEVSAPLVCQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFIYRVDRPKTTHVIGRD -> --THRPLHVPGLNEIKTVLEEGLSTNFAEVKVEIVNCPDLTKEPFLLSASGLSGNPTVLEIGGPSYLLPIVQRDKLYNIHELLQHMNYSDKFVIGAGAGPWPYINSNCELMMNLVISS--SGIKNETRIASVDKSSGNCKLETLNRN--ETRLAILANLFVSKGETGSVLKVHVKRRTGKDDFIACMQKALAHHYKDKLVGLGGTFLINEGKVKQHVMP-DFSTTPLDTLQQLDDWLKFYNMSTPLVAVGTFVSSETDLDLRVQHFHSFSNHGEGGHYHIDTTPETIEYLGYFNLGNNLYRIDQPAKSLKFGKD -> -VEKKELHVPDYNEVVKVLQDGLKANFSEVSVGVVDCPDLTKEPFTLAAPGLCGRPRMADIGGVPYLMPLVQRHKKYNFQDIAEKIELPGAFLIGAGAGPLHVVGTNSEMMTNINLNN----GDNSTYTCKMHTEDNSYILEKG--L--SLDCSLLANIYASDGKPGKVIEVKASTRTGPENFVTCMRKALKEKYGDKPVGMGGTFIIEKGKAKIHIMP-DFSEVPLDSNEKVDQWLKFFDMKAILVCLSVFISHDPGLDLRVEHTHCFNKHGGGGHYHYDVTPDDVVYHGYFVPSEYMYRIDAPTETHMIGRD -> --EKVQLHVPDLEELRGVLQAGLEDNFAEVQVSVVECPDLTKEPFQFPVKGLCGKPRITDVGGVPYLVPLVQKHKEYNMNTISKELELPGAFVLGAAAAPSRVVGMNAELMPLVLTEAEGRPAVNSSYFASINPADGQCLQEKYSNKFSDCNFGLLGNLYACEGKSGKVIEVKAKKRTGDHSLVAAMRNTLESHYPEKSLALGGTFIIQKGKAKIHIMPREFSACPLDTNDDVNNWLKHFEVRAPLICQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPKDTHEVGRD -> --EKVQLHAPDLEELRGVLQAGLESNFAEVRVSVAECPDLSKEPFQFPVKGLCGSPRITDVGGVPYLVPLVQKDKEYDMNTISKKVELPGAFLLGAGAAPCRIIGMNAELMPLVLTEAEGRPAVNSSYFSSINPADGQCLLEKYSQKFSDCNFGLLGNLYACEGKPGKVIEVQAKKRTGSHSLVTALRKTLEAHYPDKSLALGGTFIIKKGKAKIHIMPREFSACPLNTNDDVNKWLKHFEVNAPLICQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFLPAEFVYRIDRPTQTHTVGRD -> --EKYQIHVPSLEELSEVLEKGLRNNFEDAKVCVAECPDLSQAPFQFPVKGLCGKPRITDVGGVPYLIPLVHKDKVYNMNTVSKELELPGAFILGAGAVSFKTVGMNGELMPLVLTESEDKPAVNGSYFSSINPVDGKCLQEKYSERFSDCDFGLLANLFACEGKPGKVIEVRASRRKGEESLVSCMRKTMEEHYGDKTVALGGTFIIQKGKAKIHIMPQEFSSCPLNTNEDVNNWLKHFEVSAPLICQSVMVSRDPGLDLRLEHTHGFSHHGEGGHYYIDTTPNTVEYLGYFLPADFIYRIDRPTDTHNVGRD -> --VKRNLHVPSLDEIKDVLKEGLIKNFANVEVEIVDCPDLTQEPFTLSAPGLSGNSTVLEIGGPSFLLPTVQKNKLYDIQQLLNHLHYKEDFVIGAGAGPWPHINSNCELIMNMVVSL--SNVQNGTHISYVNKGNGNCELQNLPNN--ETRFALLANLFVTEGKPGKVLKIHVKKRVGNDDFIACMQKAIAQNYHNNLVGLGGTFLIKNGKVKQHVMP-DFSATPLRTEAQLNNWLHFYNMSTPLIAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRIDKPLTGVEFGKD -> --QKTRLYTPSLEEVAQVLQEGLSKNYSTVQASVTECPDLTKKPFMLAGEGLCGNPRLADIGGVPNLIPLAKREKIYNFEKIAGQLDLSNAFMIGAGCGPAHVMKVNTEMMPNLSVDGGDGKVNNQTYLGRLNPDEKSYDLFVS--P--TTDFNLMANVFCSEGKPGKVIEVKVQKRVGEENFMSCMRKVLAAHYGTKPVALGGVFLVEKGKVKIHIMR-DFSKVPLNSDEEVNKWLTFHEASAPLVVIGELISHDPDLDLRVEHFHLFSDHGEGGHYHTDTTPDIIEYRAYLNVAEFMYRIDRPTETHNIGRD -> --VEKELYQPPLDEVVQVLSNALRQNFEHVEVSVVECPDLTKPPYYLTASGLSGNPKLVEVGGVPYLLPLVNRDKVYDLKGLVEHLRRGDSYVAGAGAGPWPYAGVNCEGIVNLMVKN--GTVSQGSRIVTVEPRSSGYLQRQLPDT--ETRSALLGNYLVTDGNPGKVIKVEVKGRTGADNYITAIREGLKKYYKDKVVGLGGMFLLKNGSVKFHVMP-EFSTKPLCSDSDVDEWLHYFEMSAPITVLGTLVTGDMGLDLRVQHFHGFSAHGDGGHYHYDTSPARAHYEGYFVLGAALVRVDAPTDTHDFGRD -> -IEKRELHVPSLDEVKNVFIDALRENFAEAEIEVVDCPDLTQEPFTLSAPGLGGRVNILEIGGPPFLLPTVQRDKVYDIQSLLKDLKYGDRFVAGAGAGPWPYLGTNCEMMMNVMMDS--AKLKNGTRIASVEKSEGSCVLETLKGN--ETRFSLLANLFLCEGIPGKVLKVHAKQRIGNKDFIATMQQALAEHYRDKLVGLGGTFVMMEGKAKQHVMP-DFSETPLDSVKQLDHWLKFYDMSAPLIAVGTFVSAETELDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLGYFNLSEVLYRIDQPPNTLQFGKD -> --ECKPLHVPPLEEIADVLNKGLKKHFQDVKVEVVNCPDLTQMPFTLANKGLNGNTHMMDVGGPPYLVPFVQYDKVYDLCDIPDVVKMKSAFIIGAGAGPHPYATVNCEAIMNINIEN--SLVKQQTRIVKVNQTDGTPVQEQLPTT--ETRFALLGNFFICEGKPGQVLQVHVKKRVGCMDFIASIRGVLADHYGNRILGLGGTFLLREGKAKQHVMP-HFSETAINSDDEINQWLKFYEMSAPLIANGTLITGDYDLDLRVQHFHSFSYHGEGGHYHIDTTPDTVEYLGYFNLAQDIYRVDKPEHTHKVGRD -> ---RRALHVPSLEEIKDVLAQALPGNFAESTVEVVDCPDLTQQPFTLAAPGLGGGTKLLEVGGPPFLTPLVNREKVYDVKTLCQNVNHSGRFVIGAGAGPWPHFNSNCELIMNISISP--SEVKNETRIALVDQVDGKCVQQSLPKT--ETRFALLSNLFLSEGKPGKVIKVHAKKRTGKDNFITTIRKALAARYTKQLVGLGGTFLLKEGKAHQHIMP-DFSITPLTNDADMNKWLNFYDMSAPLIMVGTLVTSETDLDLRVQHFHSFSHHGEAGHYHDDTTPDTVEYLGYFNVGEALYRIDQPPVALGYG-- -> --EKFELFVPKLEELSEVLQNGLKENFADVHVSVVECPDLSQDPFRFPAKGICGKPRITDVGGVPYLIPVAQLDKVYDMDTVAKEVELPGAFILGAGATSSKSVGMNAELIPLVRTENDGMSAVNGSYYASINPVDDKCLLEKYSDKFKDFGFGLLANLYACEGKSGKVIEVKASRRTGAISLVTSMRKTLEIHYNDKYIAMGGTFVIQKGKAKTHVMPREFSACPLRTGEEVNKWLKHFEMSAPLICQSVLVSQDPGLDLRLEHTHCFSHHGEGGHYYTDTTPDTVEYLGYFLPAEFVYRIDRPKITHDIGRD -> --EKFQLYVPNLEELCDVLQRGLKNNFADAQVCVVDCPDLTQDPFKFPVKGLCGKPRITDVGGVPYLVPLVKVDKEYNMNTVSKELELPGAFILGAGAVSSKNVGMNAEMMPLVLTEAEGRPAVNSSWLSSINPDNNQCLLEKYSDKFSDCDFGLLANLYACEGKPGKVIEVRAKRRIGEESLVGALRKTMEEHYPDKSLALGGTFLIQKGKAKIHIMPREFSTCPLNSNDDVNKWLKHFEVSAPLICQSVMVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFMPAEFVYRIDRPSETHEVGRD -> --ERVQLHAPHLEELRGVLQAGLQENFAEVQVSVVECPDLTKEPFHFPVKGLCGSPRITDVGGVPYLVPLVQKHKEYNMNSISKELELPGAFILGAAAVPSRIVGMNAELMPAILTEAEGRPAVNSSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGQPGKVIEVRAKKRTGDHSLVTALRTTLEGHYPNKSLALGGTFIIQKGKAKIHIMPREFSVCPLNSNDEVNNWLKHFEVSAPLICQSVLVSKDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPTETHRVGRD -> -VEKKSLYVPPLQEIADALNKGLTTNFAEVNVEVVDSPDLTQKPFSLASKGLGGNPKIVEIGGPPYLLPIVDRKKVYDLKDIANLINSNPAFIIGAGAGPHPYIGVNCEGILNLNIVN--GSVEQHSRISKVDQNDENSIQEILPNS--ESRIALLANLLFSEGKPGKVLKVHVKKRIGPKDFIASIRTVLEEVYKGKLVGLGGAFLIKEGKVKQHVMR-DFSKTPLENEEDLNNWLKFYNMSAPLVALGTLVNGDGGLDLRVQHFHSFSHHGEAGHYHYDTTPETVEYLGYFITGDEIYRIDKPVATHTWGRD -> -VEKFTFHFPALEELCQVLEKGLKENFAAVEVSVVDCPDLTQDPFGFPVKGICGKPRISDVGGVPYLVPVVHLDKVYDLNTVAKDMELPGAFILGAGAVSSRRVGVNAELMPLVQTEGESKPAVNGSYSARINPANGACLLEKY--S--DCELGLLGNLYACEGKPGKVVRVKASKRTGQVSLVTAMRKSLENHYGDKPVGMGGTFVIQKGKAKIHIMPAEFSSCPLNSEEDVSKWLKYFEFTAPLICQTVFVSRDPGFDLRVEHTHCFSHHGEGGHYYTDTTPDTVEYCGYFLPAELLYRIDRPKETHTIGR- -> --QKASTHVPSLDEVAKALSGGLSQNFANVSTSVVDCPDLTKKPFMLVSEGLGGNPRLADVGGPGFLTPTPQTDKKFTFAQIAKLAELPGAFMIGAGAGPCQHVGCNSELMNNILLDSNGGVVRNNAHIAKVNPENNACVLEKL--S--CPEFNLMGNFLISEGKSGKVLEVKAGKRTGEENFVSCMRKTLKSYYGDKIVALGGVFLIEKGKANLHIMP-DFAKEPLHTNEEVKNWLKFYDMSAPLVCVGELVSHDPGMDLRVEHFHCFSEHGEGGHYHWDTTPEDVQYRGYFVLADYIYRVDQPPNITDL--- -> ---ERQLYTPRLEEIVEVLRQALGANFSEVDVSVVECPDLTQEPFTLAGKGLNGNPKILEIGGPAFLLPNVQREKVYDIQPLLKTISKSNALIIGAGAGPWPYLNKNCELMMNLSISS--SIVKNQTRLASVNTVNDCCILQTVDNK--ETRFALLANLFVSEGIPGKVLKVHVKKRIGDKDFVASIRTALADHYKDKLIGLGGTFIIKEGKAKQHVMQ-DFSKTPLNNEEELNNWLRFFNMSAPLIAVGTLVTAETDLDLRVQHFHSFSHHGEGGHYHIDTTPETVEYLGYFNTGNTLYRIDKPIISHTFGKD -> ---KRELHVPTLDEVKNVFIKALKANFEEVEVEVIDCPDLTEEPFTLAAPGLGGRLTIVDVGGPPYLLPLAQKDKIYDIQPLLKELKYGDRFVAGAGAGPWPYLNSNCELMMNVMINS--NKIKNATHIASVDKNNETCVLETLKGN--ETRFAVLANLFLCEGIPGKVLKVHVKKRIGKRDFINTMQQALTEHYTDKLVGLGGSFVIKEGKVKQHVMP-DFSDKPLNNLQELNNWLHFYDMTAPLIAVGTFISAETDLDLRVQHFHSFSHHGEGGHYHIDTTPDTVEYLGYFNLGETLYKVDQPTVALQFGKD -> -IEEKPLYTPSLEEVADVLSEGLRKTFEIVNVTVEDCPDLTREPFDLTTPGLSGDSKLVELGGPPYLTPRVRRDKVYDLAALLRHLGRDPALLAGAGAGPWPYLGVNCEGIINLSVRE--GAVTQGTRVVSVSPSQASYLQRRLPPG--ETRTALLGNYLLSEGRPGRVLKVVAEKRIGPSNFITAIRETLKERYGDRAVGLGGAFLLAAGKVKHHVMP-DFSASPLCSDEDVDRWLHYFEMTAPIMHLGTLVTGDLGLDLRVQHFHGYSAHGDGGHYHYDTTPLQVRYEGYFTLASSVIRVDRPSETHGIGRD -> -VEKFALHIPTLEELVGVLQNGLKENFADVEVSVVDCPDLTQEPFKFPVKGICGNPRIADVGGVPYLLPLVQKDKVYDLNTVAKEIQLPGAFFLGAGAVSSRVVGGNAELIPIVQAQSGKSPAVNGSYLARINPEDGGCLLEKYSSKYKDCEFGLLANLYASEGLPGKVIKVKANRRTGDQNFISCIRKTLEKCYGDKPVGMGGTFVIQKGKAKFHVMPSEFSECPLKTDAEVNNWLKFFEMKAPLICQPVLVSTDPGVDLRLEHTHGFSHHGEGGHYHEDTTPETVEYLGYFVPAEFLFRIDRPKHTHLVGRD -> --EKKKLHCPALEELCNVLESGLNKNFADVQVGVVDCPDLTKEPFQFPVKGLCGNPRITDVGGVPYLVPLVQRHKEYDMNTVSKEVELPGAFILGAAAAPSRVVGMNAEFMPLVKTETEGRPAVNGSYFSSINPADGKCLQEKYSDTFPGCQFGLMGNLYACEGKPGKVIEVRVKKRTGEDSLVTAMRKTLEAHYPDKNLALGGTFIIQKGKAKIHIMR-EFSVCPLNTDDEVNNWLKHYEIDAPIISLSVFVSKDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYMGYFLPAEYLYRIDRPQESHAIGRD -> --EKFQLHVPNLEELCQVLESGLNKNFSDVKVSVTDCPDLTQQPFGFPVKGLCGKPRITDVGGVPNLIPLVKLDKVYNMNSVSKEVELPGAFILGAGAISFKTAGINGELMPLVLTEAEGRSAVNASYFSSINPEDGKCLQEKYSDRFDDCDFGLLANLYACEGKPGKVIEVKACRRTGEDSLVSCMRKTMAEHYGEKSVALGGTFIIQKGKAKIHIMPREFSVCPLNTDEDVNNWLRHFEVSAPLIFQTVMISRDPGLDLRVEHTHGFSHHGEGGHYYTDTTPNTVEYLGYFLPAETVYRIDRPTETHNVGRD -> -IKEKELYTPPLDEVACVLSNGLTTNFKFVEVSVADSPDLTEPPYYLKSPGLTGDAKLVEIGGPPYLVPQVKRDKIYDLAKLLEHLNRDPAFLAGAGAGPWPYLGVNCEGIVNLSVRN--GTVDQGTRIVSVHPVSSGYLQQQLPND--ETRTALLGNYLLTEGKPGKVIKVVAKNRTGKSNFITSIRETLKTHYGDKVVGLGGAFVLRAGRGYFHVMP-DFSRAPLCSDAAVDSWLHYFELDAPLTVVGTLVTGDLGLDLRVQHFHGFSGAGAGGHYHYDTTPEDVHYEGYFTVASSLIRVDPPVETHTFGRD -> --EKVQLXSPSLEELQGALQAGLESNFAEVQVSVVECPDLTKEPFNFPVKGLCGNPRITDVGGVPYLVPLVKKNKEYNMNAVSKELELPGAFILGAAAAPSRVIGMNAELMPLVLTEAEGRPAVNCSYFASINPADGQCLQEKYADRFSDCSFGLLGNLYACEGKPGKVIEVRAKRRTGSDSLITALRTTLEAHYPGESLALGGTFLIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSSPLICQSVLVSRDPGLDLRMEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFVYRIDRPKEMHRVGQD -> ---KFQLHVPDLEELCQVLEKGLRKNFEEVKVCVSECPDLTQEPFKFPVKGLCGNPRITDVGGVPYLIPLVQVDKVYNMNTLAKELELPGAFILGAGAVSSKTVGMNAELMPLVLTEHEGKPAVNASYFSSVNPADGKCLQEKYSDRFCDCDFGLLANLYACEGQPGKVMEVRASRRTGEDSLVSCMRKTMAEHYGDKSIALGGTFIIQKGKAKIHIMPREFSSCPLNTNEDVNNWLKHFEVSAPLICQSVMVSKDPGLDLRVEHTHGFSHHGEGGHYYIDTTPSTVEYLGYFLPAEFVYRIDRPVETHNVGRD -> ---RRDLFVPSLDEIRDVLKEGLVKNFGEVEVEIVDCPDLTQEPFTLAASGLNGSPTVLEIGGPSFLLPMVQREKVYDVQQLLNHLQYGKDLVIGAGAGPWPYLKSNCELMTNMVVSQ--SNVRNETRIASVNKTNGNCVLGTLPSS--ETRLALLANLFVSEGKPGKVLKVHAKKRTGNDDFIASMQKAIAQRYQDNLVGLGGTFLMKDGKIKQHVMP-DFSTTPLNTEAKLNKWLQFYNMSTPLIAVGTFVSSETDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRIDKPATGVQFGKD -> --EKFQLHVPTLEELCQVLEKGLRKNFEEAKVCVAECPDLTQEPFQFPVKGLCGKPRITDVGGVPYLVPVVHMDKVYNMNTVSKELELPGAFILGAGAVSSKAVGMNAELMPLVLTELDSRSAINASYMSSINPVDGKCLQEKYSDRFHDCDFGILANLYACEGKPGKVIEVKASRRTGDESLVSCMRKTMEEHYGDKALALGGTFIIQKGKAKIHIMPREFSSCPLNTDEDVNNWLKHFEVSAPLICQSVMVSRDPGLDLRLEHTHGFSHHGEGGHYYIDTTPNTVEYLGYFLPAEFIYRIDRPTETHTVGR- -> -VEKRPLYVPPLNELVDVLNKSLKNNFQEVQVELVDCPDLTKQPFTLASEGLSGNETLVEIGGPPFLAPLVQRDKVYDLKDIAKLVDSEPAFIIGAGAGPHPYVGKNCEGIYNLKIEN--GKVDQQTRISKTDDKDDKSIQEQLPNS--ESRVALLANLFFSEGKPGKVLKVYARKRIGNDDFIASIRKSLKDGFKDRLVGLGGAFVMKTGKAKQHVMP-DFSKTPLKSDDDINNWLNFYTMSAPLIALGTLVNGEGELDLRVQHFHSFSHHGEAGHYHIDTTPDIVEYLGYFKPGQTIYRIDKPVDSHKFGRD -> -IEKRELHVPTLEEVKNVFLKALKENFEEAEVEVVDCPDLTEEPFTLAAPGLGGRLNIIEVGGPSFLLPSVQKDKVYDVQPLLEEIKYGDRFVAGAGAGPWPYKNSNCEMMMNVMINS--SKLKNQTRIATVNTEDETCVLETLKGN--ETRFALLANLFLCEGITGKVLKVHAKKRIGKKDFIATMQQALAQHYTDKLVGLGGSFVMKEGKAKQHIMS-DFSEKPLNSVKELDDWLHYYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPDTVEYLGYFNLGEVLYRVDKPPMALQFGKD -> --EKFQLHVPSLEELCEVLESGLKQNFADAKVSVTDCPDLTQEPFKFPVKGLCGKPRITDVGGVPYLIPVVQVEKIYNMNVVSKELELPGAFIIGAGAVSSKTAGMNAELMPLVLTESEGKPAVNASYFSSVNPEDGKCLLEKYSDKFHDCDFGLLANLYACEGKSGKVIEVRASQRTGQDSLVTCMRKAMEQRYPDKSLALGGTFIIQKGKAKIHIMPREFSACPLQSEDDVNNWLKHYEVSAPFICQSVMVSRDPGLDLRVEHTHGFSHHGEGGHYYIDTTPDTVEYQGYFLPAEFIYRIDRPKDTHKIGRD -> --EKYELDVPPLQELCDVLHNGLKNNFADAQVRVVECPDLSQAPFHFPANGLCGSPRIMDVGGVPYLIPLVQLDKVYNMNTVAKEVELPGAFILGAGAASSRTLGMNAELMPLVVTEIEGRSALNGSYFSYINPADGTCLQEKYSDRFDDCDFGLLANLYACEGKAGQVLEVKASRRTGEDSFVTCLRKTLEKFYSDKCLGLGGTFIMQNGEAKIHIMPQEFSTCPLSSDEEVNKWLKHYTVRAPLICQSVLVSRDPGLDLRLEHTHCFSHHGEGGHYYIDTTPDVVVYLGYFLPAEFIYRIDRPSNTHRIGRD -> ---KRDLHVPSLDEIKDVLKEGLIKNFADVEVEVVDCPDLTKEPFTLAAPGLAGNPTLLEIGGPAFLLPTVQKNKLYDIQQLLDHLQYKEDFVVGAGAGPWPYLNSNCELIMNLSVSP--SSVQNETRISSVNTTNGNCVLQTLPNT--ETRLALLANLFVTGGKPGKVLKVHATRRTGNDDFIASMQKAIALHYPNNLVGLGGTFLMKDGKVKQHVMA-DFSKTPLKTEAQLNNWLHFYNMSTPLIAVGTFVSSESDLDLRVQHFHSFSHHGEGGHYHIDTTPETIEYLGYFNLGTTLYRVDKPLTGIQFGKD -> --EKAQLHVPDLEELRTVLQTGLEDNFAEVKVSVVECPDLTKEPFNFPVKGLCGSPRVTDVGGVPYLVPLVQKHKEYDMNALSRELELPGAFMLGAGAVSSRIVGMNAELIPLVLTEADGRPAVNSSYFSSINPVDGQCLQERYRDKFSDCNFGLLGNLYACEGRPGKVIEVRAKRRTGDHSIVTALRKTLEVHYPDKSLALGGTFIIQKGNAKIHIMPREFSVCPLTSNEEVNSWLKHFEVKAPLICQSVLVSKDPGLDLRVEHTHCFSPHGEGGHYYIDTTPDSVEYLGYFVPAEFMYRIDRPKETHAVGRD -> --------------VYEVLQEGLAKNFSTVEVTVVDCPDLREKPWTLAAPGICSRTRIADVGGPPYLIPLPDLSKFYSFSDIAESAELPGGFIIGAGAGSSKFVGVNCEMMANLVIRS-EQKAAIATKIAKVNEENGSCVVENY--N--CGEFGLLGNFLISDGMPGKVLKVSVSKRTGDKNLITCMRHTLANFYGDKPVGLGGVFVIEKGKAKIHIMP-RFSETPLKTDEDVNNWLRFYEMSAPLVCVGVLESHDPGLDLRIEHFHCFSDHGEGGHYHYDVTPDEVHYTGFFAVAEKIYRIDRPLATHHVGRD -> --EKTPLHAPALEELRGVLQAGLESNFAEVQVSVVECPDLTKEPFQFPVEGLCGNPRITDVGGVPYLIPLVQNHKEYDMNMISKELELPGAFILGAAAAPSRIIGMNAELMPLVLTEAEGRPAVNASYFSSINPADGQCLQEKYGEKYSDCSFGLLGNLYACEGKPGKVIEVRAKKRTGSDSLVTALRRTLEAHYPDKSLALGGTFIIQKGKAKIHIMPREFSVCPLNTNDDVNNWLKHFEVSAPLICQSVLVSRDPGLDLRVEHTHLFSHHGEGGHYYIDTTPDSVEYLGYFMPAEFVYRIDRPKQTHTVGRD -> --EKADLVCPPLEEVAKVLEKGLSASFKSATVEVVDCPDLTQEPFHLTSKGLGGSPSLLEIGGPPYLLPLVKRDKVYDLKEVPELLGSKSVAVIGAGAGPWPYAGTNCEGVFNLSINN--GKVTNGSRIGKVDPATGTKHHAILPDN--ETRCALLANLFCSEGKTDKVLKVHCKGRTDDMDFITTVKLAIHAKYKDQPIGFGGAFLLKEGKVKQHVMP-DFSKTPINSDEDLNKWLKFFEMSAPLVAVGTFATCDPGLDLRLQHFHSFGLHGEAGHYHYDTTPETVEYLGYFSLAKVVYRLDRPAETHQFGRD -> --EKLALHCASLREVAEALQKGLLETFNHVDVKVVDCPDMREKPFMLSAEGICERPCLADVGGVEYLAPLAQKDKVYDFKLIAESIDMPTALMIGAGAGPRPHIGTNCEMMANVKLGDE---DLINTRIAKITEDG--SELIHL-KD--STKFCLLGNLYVSEGKPGKVIKVIAKERKGSENFVTAMRKILADYFKDKPVGIGGVFIIKKGKAKLHIMP-DYSDKPLRSDDDINNWLKFFNMSAPLTCLSTFVSHDPGLNLRVEHTHCFSDHNEGGHYHYDITPDSVEYEGYFNVCHELFRIDRPSTRQEFGRD -> --EKVQLHAPVLEELRGVLQAGLGANFAEVQVSVVDCPDLTKEPFLFPVKGLCGKPRITDVGGVPYLIPLPQTHKEYNMNVISKELELPGAFILGAGAAPSRITGMNAELMPLVLTEAEGRPAVNGSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGKPGKVIEVRAKRRTGSNSLVTALRKTLAAQYPEKSLALGGTFIIQKGKAKIHIMPREFSACPLNTDDEVNNWLKHFEVSAPLICQSVLVSRDPGLDLRVEHTHGFSHHGEGGHYYIDTTPDTVEYLGYFLPAEFVYRIDRPKDTHTVGRD -> --KMHSYHVPDLHEVADVLQKGLANDFAEISAAVVSCPDLTKEPFHLAAEGLGGSPRICDVGGVPYLVPLYNPAKKYNFQEIANLAGVPDGFFVGAAAGPFHVVGSNSELMPNIRCGT---SRRNETHYAKITESG-GHLMEKVPQD--SSDFGLMSNLFLSEGQPGSVLHLSLKRRIGKDNLTAAIRKVLLEAFGEKPVGLGGVFLIKKGKAKLHIMP-DFSTVPLKSDDDVDQWLRYFEFPAPLICLSVMSSCDPGWDLRIDHTHCFSTHGVGGHYHYDTTPEEVEYECFFNVAEKLVRIDQPKETHNIGRD -> --EKFQLHVPNLAELCQVLQSGLNKNFSDVKVSVTDCPDLTQEPFGFPVKGLCGKPRITDVGGVPYLIPLAQPDKVYNMNTVSKEVELPGGFFLGAGAVSCKTVGMNGELMPLMLTEAEGRPAVNASYFSSINPVDGKCLQEKYSDRFHDCDFGLLANLYACEGKPGKVIEVRACRRTGEDSLVSCMRKTMEEHYGEKSVALGGTFVVQKGKAKIHIMPPEFSACPLNTNEDVNNWLRHFEISAPLIFQTVMVSRDPGLDLRVEHTHGFSHHGEGGHYYIDTTPNSVEYLGYFLPAEFIYRIDRPTETHNIGRD -> --EKKALHVPELGELATVLQDGLKSHFASVSVSVVDCPDLTQQPFTLAAPGLCGSPRAVDVGGIPNIHPLPKLEKIYDMEKVAELADVPGAFMIGAGAGPYKHVGVNSELMPNLIASTNARERNSETYDMRLDTESGKPILEKC--A--SAECALMVNLYCSEGKPGKVLEVKASKRTGESDFVAAMRKVIQAKYGDKAVGLGGTFLIDRGKAWLHVMP-DFCPTPITNLKEVEAWLKFFEFDAPIVCLSVFYSYDPGLDLRIEHTHCFSHHGAGGHYHYDTTPEDVVYRGYFHPAEWVYRVDRPTEK------ -> ----LDLLVPSLEELAKVFKDGLKKNFCEVDVDVVDCPNLQNSPWNLAASGICGNAKIADIGGPAYLLPLAQLDKVYDMNIIAEKAGCPGGFCIGAGAGNSHYVGVNSEMIANICTKSKSPEAVIGSRISKVHMEDESCVLQDY--K--CCDFALMANVLISEGKPGQVLRVKASKRTGKDNFITSMRTALAAKYGDKSVGLGGVFVIEKGKAKFHIMP-DFSKTPLKTDGXVNNWLKFYDMSAPLVCVGVFESHDPGLDLRIEHFHGYGNHGEGGHYHYDVTPDDVQYVGYFTPATXLYRMDKPPSQRKFGA- -> --VEKPLFVPPLEEIRDVLKQALPNNFAEVAVEVVDCPDLTKQPFTLAAPGLGGKQKLIEIGGPPYLLPLVQREKIYDVQSLLKRLNYGDILLIGAGAGPWPYLNCNCELVMNLAIAP--SGLKNETRIGSVNKQANCCVQQTLPEK--ETRLALLANIYVSEGKPGKVLKVHVKKRIGQDDFIASIRKAVRSYYKDKLVGLGGTFLLKEGKAKQHVMS-DFSTEPLNSDEALNDWLYFFDMSAPLIAVGTMVTDEAGMDLRVQHFHSFSHHGEAGHYHIDTTPDVAEYLGYFNVGEALYRVDQPPFVQNFGKD -> --TTRPLHQPPLDELMNVLAGGLTTNFEEATIEIADCPDLDEWPYLFYRKGLCGNPIILDIGGPAYLLPTAQKDKFYDIKLILRHLNYNHDLVIGAGAGPWPHTGCNCELIMKVNIQVRNNGVANGTHYAFVNKSTGECSVTRVLANEDETTFALMANLYVSEGNPGKVIRVRAKKRTGKLDFISCMQNALENHYKDNLVGLGGMFVMKNGKIKQHVMP-NFFDTPLNTETQLNNWLHFYDMETPLVAVGTFVSAETDLDLRVQHFHSASNNQLGGHYHIDTTPDTIEYEGYFNVATTLYRVDQPPNKLQFGKD -> --EYKPLYKPPLQELADVLNQNLTYNFAEVHAEVVDCPDLRKEPFTLASEGLGGNPRVVEIGGVPYLAPIAQLNKVYDLKDIERFSGLKSAFIVGAGAGPHPYAGVNCEGIINMNVKD--GKVEQQTRISKVVPSDGSQVQEILPNS--ETRIALLANLFYSEGKPGKVLKVHVKKRIGSDDFVTSIRETLAKRYFDKIIGLGGTFLLKEGKAKQHVMP-AFSKTPLNSGKDIDNWLKFYNMSAPLIAVGTLETGDPGLDLRVQHFHSFSHHGEAGHYHIDTTPETVEYLGFFNIGEYVYRVDAPAVSHSFGRD -> --EHKPLHVPPLEEVSSVLEAALKKNFAEAAVSVVECPNLTKTPYNLGAAGLCGSPRLADVGGVPYLMPTAQKDKLYDIKDLAGCVDLPNSFIVGAGAGPHKYIGVNSELMANVVVGN---EACNGSRAAKVDDAG-KCELLRLPQE--QTGCALMLNMFASEGKGGKVLKVQAKKRIGDKNLVSCLRQALENHYGDQPVGLGGTFRLLQGKAKIHVMP-DFSPVPLTCDNDVNKWLNFYDMEAPMVFLSTLISRDPGLDLRVEHSHGYG-DDRGGHYHYDTTPDTVEYEAYYNVAEFIYRVDKPVATHGFGR- -> --ENCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTAQRDRTYDLADLPGLMNVKDGLMIGAGAGPWQHLNTNCEMMTNLSLEEGKSNIVNGTRLATVDPAG-QRMLHVVPPEQEQTRCSLLNNLLISRGQPTPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSVHGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSETHRVGRD -> --TSRPLHQPPLNELMSVLTEGLTTNFAETTVELVDCPDFGRWPYNFYREGLCGTPIILEVGGPAYLLPTVQRDKFYDIKTILKHINYNRDLVIGAGAGPWPHTSSNCELVMKLNVVNYGMGVANGTHYAFVNKRNGECILQRLPANEDETTFALLANLYVCEGKPGKVIKVHAKKRTGKLDFISCMQKALGNQYKDKLVGLGGTFVMNNGKVKQHIMP-DFSDTPLNSEAQLNEWLHFYDMKTPLIAVGTFVSAETDLDLRVQHFHSAYESRLGGHYHIDTTPETIEYEGYFNVAATLYRVDQPPNKLQFGKD -> ---KLPLKIPDEAELVSVLSKGLLKNFQDVSVNIVDCPDLREKPFQLAAEGICGNPCVADIGGPPFLLPTVHKEKIYNIKTISEISGQQDGFFIGAGAGPAHLIGVNSEMMCNVNLNK-P--DGCQTYIAKVNPENGCFNLKQI--E--HSSFMLMANLLCCEGKQGKVIEVKASKRIGDDNFPTAIRKTLKSQYGSEPVALGGVFIIENGKAKLHIMP-DFSCKPINNVTELNNWLRFYEANAPLVCLGELISHDPDLDLREEHFHCFSPHGQGGHYHYDVTPEEVSYRAYFSVAKTLYRIDKPEHPLNFGKD -> --EKRQLHTPDLSHVAQVIESGLKENFKEASVNVVDCPDLTSSPWQLAAPGLGGAPRLLDVGGVPYLMPLIQREKVYDLAQVASLAGLPNGFILGAGAGSYRVAGVNCEMMANIKFSDSGAPHNIGSYSAKVSTEDGSAIIEKFP----YTEAGPLANLLLCEGTPGPVLEIKARKRVGEENFVTCMRKSLAAYFGEGPVGLGGVFMIKKGKAKLHIMP-DFSQTPLTTNEGVNKWLQFYNMSSPLTCLSVFISCDPGLDLRVEHTHCFSSHGDGGHYHYDVTPQEVEYHGYYVIAEEIVRIDRPIKTHQIGRD -> ---VKKLYKPNLEELQYALTNGLKSNFAEVSVDVVDCPDLTKEPFGLKSKGLGGSTAVVDVGGPPYLLPNVFRDKLYDFRDVAKTVNLNPCFIVGAGAGPWPYANTNCEMIANVVVQD--GKVDSGTVISKISKDTGKMEVEFISKD--ESRFALLANFFVSEGKESKVLKVNCKKRKGNLDFVTAMRTSLANHFYDKYIGMGGLFVVKKGKVRQHVMQ-DFSEKPLNTEKDLNEWLRFFEMSAPLIALGAFLSQDVDFDLRVQHFHSFSHHNEAGHYHYDTTPDDIEYEAYLNVADTLHRIDQPLVTHKFGRD -> -VQKMPLHQPPLEEVAEVLQKGLANNFSTAEVKVVDCPDLTAAPFDLAEKGLSGRPRILDVGGPDYLKPFPQKEKKYSFADVSNLGELPGSFLIGAGAGPCHHTGTNCELICNVQLGE---GGSNKSRIVKVNEGDGSYTIMEE--K--SGEFSLLGNFFLSQGKPGKVLELKVKDRTGPENFVSCVRKTLAAHYGDKTVGVGGTFLLQTGKANIHVMP-DFSKTALETDEQSDNWLKFYEMDAPLIHVGEIVSGDPKLHLRCEHFHCFSHHGQGGHYHYDTTPNSASYLGYLNLAEAVYRIDIPQEKK----- -> --EKIQLHVPSLEELSAVLQTELQANFAEVKVSVVACPDLTREPFLFPAQGLCGNPRITDVGGVPYLVPVAKKEKEYDMNVISKEVELPGGFFLGAGAVASRVVGINAEFMPIVLTEAEGRPAVNGSYFSCINPVDGQCLQEKYSDKFSDCHFGLMANLYACEGKPGKVIEVLAKKRTGDQSLVTALRKALENHYPDKSLALGGTFVIQKGKAKIHIMPREFSACPLNTNDEVNNWLKHFEVCAPLICQSVLVSKDPGLDLRIEHTHIFSHHGEGGHYYIDTTPDIVEYVGYFMPAEYVYRIDRPKETHAVGRD -> --ESCQLHVPPLDELAHVLRQGLALHFAFVQVDVVDCPDLSQSPFHLTAPGLGGDPSLVDLGGVPYLVPTVHRDRIYDLADLPAAMNVKDGSMIGAGAGPWQHLETNCEMMTNLSGKSSSLVVDNGTRLATVDPSG-RRILHVVPPK--QTRCSLLNNLLVSRGLPTPVLRIRCQKRTGPDNFVTCMRNTVRQRYGHQPVGMGGVFMLENGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSTHGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSQTHGVGRD -> --TSRTLHQPPMDELMNVLAEGLTANFAEATVEMADCPNFSGWPYNFYREGLCGNPIIFEVGGPAYLLPTVQRDKFYDVKSLLRHINYNYDLVVGAGAGPWPHTGRNCELIMKLNIVNLGMGVANGTHYAFVNKSNGECILQRVVANEDETTFALLGNLYACEGKPGKVIKVRAKKRTGKQDFISCMQKALEKHYGDKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTSEAQLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFENKLGGHYHIDTTPDTIEYEGYFNVAATIYRVDQPPNKLRFGKD -> --RIHEYHVPPLENVAKVLQEGLQKSFTEVSVTVEDCPDLKKAPFHLAAEGLSGLPRICDIGGVPYLIPLAQPEKRYNYEEVASLAGVPDGFFVGAGAGPCHIIGTNSELMPNIKCSGSGSLTRNETHYARICEDGKSHLMEKVPNG--TADFCLMGNVFLSQGKPGKALRLRLKRRTGSDNLTTAIRKILLETFGDKPVGLGGVFLISKGKAKLHIMP-AFSKTALTSDEDVDKWLHYFEFRAPLICLSVMSSCDPGWDLRIDHTHCFSTHGAGGHYHCDTTPDEVEYECWFNVAEKLVRVDQPKETHQIGRD -> --SQRQLFAPSLQEIKNVLSPALAENFSEVSIEVVDCPDLTQQPFTLAAAGLGGSKTILEVGGPSFLLPSVQRDKVYELKSILNRINNGKKFVIGAGAGPWPRLSRNCEMMMNVIVS--PTDLKNETRLSWVGPNE-KCILEESLEN--DLRFALLANLYLSEGKPGKVLKVHAKKRTGNLDFIATMQKALESHYKDKLVGLGGTFLLKQGKAKQHVMR-DFSSVPLTTEKALNDWLKFYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPETVEYLGYFSVAELLYRIDQPAVGVTFGKD -> ----RSLHQPPADELLNILAEGVTANFKEASVEIVDCPNFNQYPFNFYREGLCGNPIILDVGGPSYLLPTAQKYKFYDIKTLLQKLNYNNALVIGAGAGPWPHTGSNCELIMKVNIVNHDMGVANGTHYAFVQKSTGKCILHRVVANEDETTFALLANLYICEGKPGKVIKVRAKKRTGNLDFISCMQKALEGHYGDKLVGLGGTFMVKNGKVKQHIMP-DFSDTPLNTETQLNEWLRFYEMETPLIAVGTFVSAETDLDLRVQHFHSANEIGLGGHYHYDTTPDTIEYEGYFNMADTLYRVDQPLNKLQFGKD -> --EKFKLFVPELKDLCEVLQKGLKNNFADVQVCVVDCPDLTEDPFRFPVKGLCGSPRITDVGGVPYLVPLVKVDKDYNMNSVSKDLELPGAFILGAGAVSSKTVGMNAELMPLVLTEAEGRHAVNSSWISSINPADGQCLLEKYSDQFSDCNFGLLANLYACEGKPGKVIEVRAKIRTGEESLVGALRKNMEKHYPDKSMALGGTFIIQKGKAKIHIMPREFSACPLNTDEEVNQWLKHFEVSAPLICQSVMVSRDPGLDLRVEHTHCFSYHGEGGHYYTDTTPDIVEYLGYFLPAEFVYRIDRPEKTHNI--- -> --ERQALFQPQFEDVVKALSKGLRENFETVNVSLEDCPDLTQEPFHLAAKGLGGSPKIVDLGGPPYLLPNVDKSRYYDCALLGEICQIEPAFIVGAGAGPFQYVGTNSEMIANLIVEK-GKENKVGTRIVKLQNHQDKIEVQVLPKE--ETKCALLANFFLSQGKSGKVIKVHVKKRTGSKDFVTSMREALKSQFGDKAVGLGGAFLVKEGKVRQHVMS-DFSKTPIHTEEELNSWLNFYEMSAPLVALGILISVDPGMDLRVQHFHSFSLHGEGGHYHYDTTPDSVEYLAYLNMAGELIRIDRPEVTHQFGRD -> ----TNLDTPSLAEVRDVLARDLKKTFDYVDVQVVDCPDLTEEPFFLAGKGLGGETSLIDLGGPPYLLPLVKRDKVYDFKQLVKQLKVTPSLLMGACAGPWPYFGKNCEGVCNVLVDG-DNYFKSCSYVGKVTDGDEKLECLPIPDS--ETRFALMANLYCSQGKPGKVLKVNCKKRTGKKDFITAIRTGLAAGFPNKYVGLGGAFLLKEGRAKQHVMR-DFSKTPINTEEELNNWLTFHDMSAPLVAVGTLISNEVDFDLRVQHFHSFSKHNEAGHYHYDTTPETVEYLGYFNVAERLHRVDKPKQTHQLGRD -> --ETFDLSIVPLEDLAAGLNEHLKYNFEKVKVEVKDCPDLTQPPFTLACKGLTGNERIVEIGGVPYLLPKPRKDKLYDLKDLSKILNLDPCYITGAGAGPWPYAGTNCEMIINMEHNG--DKVNNKTRIAKVNVTDGKCIQEVLPND--ECRNAVLSNLYCSSGEQGKVLEISCSKRIGNDDFITSIRKILGENFKDKILGLGGVFVIKKGKVKQHVMP-DFSNREISSEDDLNKWLKFYEMNTPLIAVGTLVNNDPGLDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLAYFGLGEKLYRIDRPSQTHNYGRD -> --EVADLHVPPLDEVAAAIENGLKGNFLHAEVQVVDCPDLTKEPFHLAASGLSGDPSLVDLGGVPYLIPSVRRDKIYDLAEIPSLIDFRESMMIGAGAGPWFHVGTNCELMLNLSISGDETGVRNFSRLATVHQKE--HRQQQLPAD--QTKCALLVNFLVSKGEMSKVLRVECSKRTGSENFITCIRQTLNQHYPDKAIGLGGTFIIDNGKAKLHIMP-DFSSCPLETNEQMDNWLHFYEATGPLVALSTLVSRDPSLDLRMEHSHCFSLHGDAGHYHYDVSPDTIKYYGYFVVAEKIYRIDRPTVTHLIGRD -> --EEKTLHTPSLDELKTVLSKGLVNNFTEVDINIVDCPNLTQAPFHLASEGLCGRETLIEIGGPPFLLPTVDITKLYDLVSICQKSLNAEHFALGAGAGPWPLVNTNCEGIFNLKNHA-NGHIVSESHLAKITKDRKKCILEKIPNT--DTRCALLANIFACDGKAGKVLKVHCKKRIGNDDFIASIRNTLQKHYGDQTVGLGGVFLLKNGSAKQHVMS-PFSEEPINTEEELNSWLNFFNMPAELIALGTLITNEYDLDLRLQHFHSFSKHGVGGHYHNDVTPDIVEYEGYFMVGRKIVRVDKPKVTHKFGRD -> --EEKPLYVPSLDEVCKVVASGLKSNFETVQVEVVDCPNLTEDPFHLASQGLNGSPTLLEIGGPPYLLPHVDYTKLYDLVAISERANVTKKLAIGAGAGPYPYVDSNCEGMFNLKVHA-NGHVLSESHLARVTPDRKKVLLEKIPNT--ETRCALLGNIFLSEGKPGKVLKVKCKKRTGNKDFIASIRTTLEQHYGERTVGMGGVFLLKNGKAKQHVMS-PFSETAIYTEDELNSWLNFFDMSATLIAVGTLVTNECDLDLRLQHFHSFSRHGEGGHYHIDTTPDTVEYEGYFNLGEKIVRVDKPVNTHKFGRD -> --EILKLHCPSLNDISKVLKKRLIGNFATVEVNVTDCPNLTAPPFHLAAAGLCGSTRIVDVGGPPYLLPLPQLDKVYNIADIAKRVNLPSAFIIGAGAGPYNLVGVNSELIPNLKLDPPTGCSAMQSYISKVDLGDGSCIQETI--N--STDFSILGNFFFSEGAQGKVLEVKAKERIGEENLISCIRKALSEEYGDQPVGIGGAFLIERGKAKIHIMS-DFSKEPLENDEAVDEWLKFYEMSAPLVCLGECVSADPGMDLRVEHTHCFSQHGEGGHYHYDTTPEEVAYHGFFNVAECLYRVDRPGETHDLGR- -> ----RTLFTPTLNDIKNVISPALSKNFLETSVEVVDCPDLRESPFKLASAGLGGHPKLCEIGGPPFLLPCVQRDKIYDVRTISKQIHYGDKFIIGAGAGPWPQLSQNCEMMMNLAVDS--AHVINETKLAWVGEEN-QCVLQKCVDS--DTRLALLANLFISEGKPGKVVKVNAKTRIGDLDFIASIQKALSVYYKDQLVGLGGTFLLKKGKAKHHVMP-DFSSVPLTTEESLNNWLRFYDMSAPLVAVGTLVSSESDLDLRVQHFHSFSDHGEGGHYHIDVTPSIVEYLGYFNVADCLYRIDQPTSGLTFGKD -> --QKMALHQPSLSEVAEVLQKGLAQNFSFSEVSVVDCPDLTKPPFDLAAEGLGGQPRIVDIGGPDYLKPWPQKNRLYNFESIADLAELPGSFLIGAGAGPHLNVGVNCELVCNAKLGL---NARNRTRIVKVDEKVGTFKLEEE--T--SGEFSLMGNFLISEGKPGKVLEIKAKNRTGTENFVSSIHKTLTAHYGDKAVGVGGTFLFQTGKANIHVMP-DFPTTPFENNEQIDSWLRYYEMDAPLINVGEIVSADPENNLRREHFHCFSNHGQGGHYHYDTTPDNASYLAYFNLGEVLYRIDLPE-------- -> --TTRTLHQPPLDELINVLAGGLTTNFAEATIELVDCPNFNGWPYNFYREGLCGNPIILDVGGPAYLLPTAQKDKFYDIKLLLRHLNYNHDLVIGAGAGPWPHTRCNCELIMKLNIQVINNGVANGTHYAFVNKSNGECILERIVANEDETTFSLMANLYVCEGNPGKVIRVRAKKRTGKLDFISCMQKALENHYEDKLVGLGGMFVMKNGKVKQHIMQ-DFSDTPLNTEAQLNNWLRFYDMETPLIAVGTFVSAETELDLRVQHFHSAYEKRLGGHYHIDTTPDTIEYEGYFNVAATLYRVDQPPNKLQFGKD -> --KSRTLHQPPLDELMNVLTEGLNANFAEATVELADCPSFDTWPYNFYREGLCGNPIILDVGGPPYLLPTVQRDKFYDVKSLLRQLNYNNSLVIGAGAGPWPHTGSNCELIMKLNVVNLGMGVANGTHYAFVNKSTGGCILERIVPNEDETTFALLANLYICEGKPGKVIKVRAKKRTGELDFISCMQKELEKRYGKKLVGLGGMFEVKNGKVKQHIMP-DFSDTPLTSEAQLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAYENNVGGHYHIDTTPDTIEYEGYFNVAATLYRVDQPPNSMQFGKD -> --KSRTLHQPPLDELMNVLGEGLTANFAEAAIEMADCPELDKGPYNFYRKGLCGSPIILEVGGPSHLLPVVQRDKFYDVKSLLRQLNYNHDLVIGAAAGPWPHTGRNCELIMKLNVTNLNMGVANGTHYAFVNKSTGECILERVAADKDETTFALLANLYVCEGKPGKVIKVRAKKRTGNLDFIACMQKALEKRYGDKLVGLGGMFEVKNGKVKQHIMP-DFSDTPLTTEAQLNNWLHFYEMETPLIAVGTFVSAETDLDLRVQHFHSAYENKLGGHYHNDTTPDTIEYEGYFNVAATLYRVDQPLNKLQFGKD -> --TTLKLDCPELEEVANALQKGLTQYFAEVEVAAVECPDLREKPFNLAAKGLGGKSAVIDIGGPAFLLPLPDESKIYDIKDIAKIVDLKSCFVVGAGAGPWPYIGKNCEIMANVLIDSCANSTVQKTHIAKVNNKTENCEVEVLPSE--ETRCTLMANLYACEGTPSKVLKIVCKKRKEEENYITAIRLVLEKAFPNQTLGLGGAFLLNKGKAKQHVMP-EFSKVPIKSHKDLDNWLKFYEMSAPLIAVGTFISKDVALDLRIQHFHSFSNHEEGGHYHYDTTPETVEYVGYFNLGQKLYRIDQPERKQYFGKD -> --EEKPLYTPPLEEIRDVVAAGLTSNFETVTVEVVDCPNLTEDPFHLAGQGLNGNPTLLELGGPPYLLPHVDYTKLYDLVSISQKANCTKKLAIGAGAGPYPYVDSNCEGMFNLKVAA-NGHVLSESHLAQITPDRKRVLLKKIPNT--ETRCALLGNIFVSEGRPGKVLKVSCKKRTGPKDFIAAIRTTLEQHYGERTVGMGGVFLLKNGKAKQHVMS-PFSETAINTEDELNTWLNFFDMSATLIAVGTLVTNECDLDLRLQHFHSFSRHGEGGHYHNDTTPDVVEYEGYFNLGERIVRVDKPVNTHKFGRD -> --EEKPLYVPSLSELTEVLTNGLKENFADVTVTVVECPDLTVAPFHLAANGLSGSPAIVEIGGPPYLLPLVDRSKLYDLAEITRKV-LPNAIVLGAGAGPYSLINSNCEGIFNLKIHS-DGTVVNNTHIAQVSPGNETCALIKVPNA--ETKCALLANLYLSEGKPGTVLKVQCKHRTAPENFVSSCRNAVTKAFADKVVGIGGVFLLKNGKAHQHIMR-DFSKTPIYTEDELNGWLKFYEMPGTLIAVGTFITDEADLDLRLQHFHSFSTGNWGGHYHYDTTPDTVEYEAYFNVGERVVRIDKPTNTHKFGRD -> --EKVKLHAPALEELRGVLQAGLGANFAEVQVSVVECPDLTKDPFQFPVQGACGSPRITDVGGVPYLVPLVQKHKEYDMNVLSKELELPGAFLLGAAGAPSRILGMNAELMPLVLTEAEGRPAVNRSYFSSINPADGQCLQEKYCDKFSDCSFGLLGNLYACEGKPGKVLEVRARKRTGVHSLVTALRNVLHSHYPDKSLALGGTFLIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLVCQSVLVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFMPAEFVYRVDRPKETHGVGRD -> --TSVKLDCPELEDVAIALQKGLPQYFAETEVAVVDCPDLRKGPFNLAAKGLGGNTAVIDIGGPAFLLPLYDETKIYHMKDIASTVGMKSCFIIGAGAGPWPYIGKNCELMANILIDDSTSSIVQKTHIAKVNDKTEDVEVEVLPNS--EMRCSLLVNLFACEGTSSKVLKVFCKKRKEDENFITAIRTTLEKAYPDKTLGLGGAFLLKEGKARQHCMP-EFSKVPIRSNNDLNNWLKFYEMSAPLVAVGTLLSKDIDLDLRVQHFHSFSNHGEGGHYHYDTTPETVEYLGYFNLGQTLYRIDQPEKKQYFGKD -> ----RDLHVPSLEDAQKALSKGLKNVFAEVSVDIVDCPDLSAEPFNLACKGLGGTTSVVEVGGPPYLLPKVDRQKVYDVKDIVKAIGLQQCFVIGAGAGPWPFIGKNAEMVANVYIDG--NNVKSLTHIAKLKDDGNNIEVSVLPNT--ETRFALLANLFFSEGVQSKVLKVHCKKRTGSDNFVTAMRNALHDDFPDKVVGVGGAFLLKSGKALQHVMP-DFSKSPLNSDEELNKWLEFYSMSAPLVAVGTLVSSDIELDLRVQHFHSFSSHGEAGHYHQDTTPNEVEYLGYFNLGQKIYRIDKPPLTHSWGRD -> ---SRALHQPPLDELMNVLAGGLTANFEEATVEMADCPNFSGRPYYFFKEGLCGNPIILEVGSPSYLLPTVQRDKYYDIKSLLQQLNYNHDLIIGAGAGAWPLRDSNCELIMKLNLKNDNFQVRNGTHYAFVDKNNQGCKLERLAENDNITTFALLANLYVCEGKPGKVIKVRAKKRTGKLDFIACMQKALEKHYENKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTTEADLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFDPGLGGHYHIDTTPDTIEYEGYFNVATTLYRVDQPPNKVQFGKD -> --HTKSLYQPPLTEVAEVFRSYLPTNFQEVNVSVVECPDLTSKPFLLAAGGLNGNAKLLEIGGTQYLLPLVTREKLYDLLDIAKSVALEPAFLIGAGAGPHPFIGANCEGIVNLKIEK--GVADQQTRTSKVEGADEYMVVQILPNN--ETRIALLGNIFASEGKPGKVIKVHVKKRTGAKNFIETLRNAIEEKYGDQLVGIGGAFLIAEGKAKQHVMR-DFSKTPLTSEDDVNNWLKFYEMSAPLTALGTFTSNDGDLDLRVQHFHSFSTHGEAGHYHYDTTPDTVEYLGYFNVAQEVVRVDKPESGSKLGRD -> --EEKALHTPSLGEIRDVLATGLKSSFATVNVEVVECPDLTKAPFHLAGRGLNGSPTLVEIGGPPYLLPNVDRSKLYDLVSVSQRALHDTKIAIGAGAGPFPLVNSNCEGMFNLRYTP-PGTVVSESHLAVISPTDRTVTVHKIPNT--ETRCALLGNILVAEGKPGQVLKVSCKRRTGKKDFIASIRTCLEGHYGERTVGLGGVFLLQTGKAKQHVMS-PFSETPINTEEELNEWLNFYDMPAPLINVGTLVTTECDLDLRLQHFHSFSTHGHGGHYHIDTTPDIVEYEGYFIVGERIVRVDKPVNTHKFGRD -> -VQKIDLKPPPLEDLIDCIRSGLGQSFKSISVSVDQCPDLRQAPYHLAFTGLCERPRIADVGGQPNLAPTPDLTKKYDLLEIARLMEMPEGALLGAAAGPFHVVGMNSELMPNLSWKN--KEVSNETHFAKVRSDG-SAVCEKL--S--SHDCGLMANLFGSLGRPGPLLHITASSRTGPLNFTEAIRGALQDAFGTRTISLGGVFLISEGKAKLHVMP-DFSPTPLVTDKQKEEWLKFYEMKAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPADVKYEAWFNIAEVLYRIDRP--------- -> --TSRTLHQPPLDELMNVLAGGLTANFAEATVEMVDCPNFNGWPYNFYQEGLCGNPILLEVGGPAYLLPTVQTDKFYDVKSLLRQINYNDTLVIGAGAGPWPHTGCNCELIMKLNIVNLGMGVANGTHYAFVNKSNGECKLERIVANEDETTFALLANLYVCEGKPGKVIKVHAKKRMGNLDFISCMQKALAKHYEDKLVGLGGMFEVRNGKVKQHIMP-AFSDTPLTSETQLNNWLRFYDMKTPLIAVGTFVSAETDLDLRVQHFHSAFENRLGGHYHIDTTPDTIEYEGYFNMAATLYRVDQPPNKLQFGKD -> --KIHDYYVPLLENVATALQRGLTESFAEVLVRVEDCPDLTKAPFYLAAEGLSGSARICDVGGVPYLIPVARPEKRYNYEEIALLAGVPDGFFVGAGAGPCHVIGTNSELMPNIKCGNSGNLTKNKTYYARIREDG-SHLVEKVPHG--SADFSLMGNVFLSEGKPGKVLHLHLKKRTGPDNLTTSIRKILLKEFGDRPVGLGGVFLITKGKAKLHIMP-GFSKDPLTNNEDVEKWLHFFEFSAPLICLSVMSSYDSGWDLRIDHTHCFSTHGAGGHYHNDTTPEETEYDCWFNVAEKMVRIDQPKETHQIGRD -> --EEKPLHVPPLQELQSVIQGALDSNFGHVDVSVVPCPDLKGSQFGLVESGLGGKPTLLEAGGPPYLRPLVQRDKLYNLKEITRKIQGPGKFAVGAGAGPWPIRGSNCEGIFNLSVSE-EDKLTNGSYTATVRGEKEECVLEKISDS--EPRCALILNLFLSQGQPGEVLKITAKQRTGEQNFIECIRKGLEQHYQDKPVGLGGIFLIKKGKVHQHVMR-DFSKTPIYTTEQIQQWLKFYEMPAQLNALGTLVTKDLGLDLRLQHFHSFSFTNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDRPRLTDQLGRD -> --EEKPLYTPSLVEIRDVLASGLKTCFATVNVEVVDCPDLSKAPFHLAGTGLNGSPALIEIGGPPYLLPTVDGTKLYDVVSVAKRALHDDGIAIGAGAGPFPLVDSNCEGMYNLRYTP-PGSVVSESHLAMVNAKG-EVIVRKIPNT--DTRCALLANLLVSEGNPGPVLKVSCKRRTGNKDFIASIRTCLEDRYGERTVGMGGVFLLQSGKAKQHVMS-PFSKTPINTEEELNEWLNFFDMPAPLINVGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVVGERIVRVDKPVNTHKFGRD -> --SQRQLFVPSLQEIKNVVSPALAENFSEVFVEVVDCPDLTQQPFTLAAAGLGGVKKILEVGGPSFLLPIPQRHKIYELKSILDCINDKRAFVVGAGAGPWPRLSKNCEMMMNVVVSA--KDLKNETRLSWVGRNE-ECILEESLGN--DTRFALLANLYVSEGTPEKVLKVHAKKRTGKLDFIATMQKALQAHYKDKLVGLGGTFLFKQGKVRQHVMR-DFSTAPLTTENALNNWLKFYEMSAPLVAVGTFVSAQTDLDLRVQHFHSFSHHGEGGHYHIDTTPDIAEYLGYFGVAESLYRIDQPAVCVDFGKD -> --EEKPLHQPPLQELKQVIQSTLLKNFENVSVDVTSCPDLTASPYNLMDSGLGGSPILLEAGGPPYLLPLVQREKLYNIKEMCQKAMGGEGLAMGAGAGPYPLRNSNCEGIYNMAVSA-DGKITNGSYTAKVSGKEEACALEPIPNS--EPRCALLLNLFVCRGEPGQVIKITCKKRIGKQNFIECIRQGLLEKYGDKCVGMGGLFLIKRGKVFQHVMR-DFSKTPITSEVELNQWLKFFEMPATLNAVGTLITHENDLDLRLQHFHSFSTSNWGGHYHYDTTPETVEYEAYLNVAERVVRVDKPIETHKFGRD -> ---SKILDVLPLQDVARCLEEGLLANFSTASVEVVDCPDLTQSPWSLASQGLCGSTRLLDIGGVPFLMPVVKRDKLYDMKDYPRLTGSPQGLVIGAGAGPWPYLNRNAEMMPNMFVNS-DNSIRQETRITRTHDEDGSYSTLKLPSS--ETRNAVLGNVFISDGKPGKVLRIKASKRIGDNNFVTCMRESLNSAYPDKAIGLGGVFCIQKGTAKFHVMP-DFSPCPINNNDQVNEWLQFYEMTAPLTVLSVLISRDPGLDLRVEHSHGWGENNQGGHYHYDTSPDTVEYIGYYNIADTCYRIDKPVDTHNFGRD -> --AKLELYQPEANELRSVLEKGLKNSFEEASVQIIDCPNLKKEPFNLAAKGICGRPTLIDVGGVRNLQPVPLRNKIYNLDKLTQIAHNPEAFLMGAGGGPFHITSVNCEVSILTRWDPHTGHGRNLSYIARLDPVN-EYKLLQMP-E--NRECGLMLNALVCEGKEGKVMQVKAKKRTQDTNFITAMRETLKVAYGDKPIGFGGVFLLQSGNAKLHIMP-DFPIYPLNDDATVNSWLKFYDMHAPLACLSTFVTNDPNMDLRIEHTHCYSDHGQGGHYHHDTTPDTAEYLGYFVLCNTLYRIDKPAMLHR---- -> --EEKTLYQPPLEELREVIQSTLAKNFENVSVEVTACPDLKSAEYGLMDSGLGGSPMLLEVGGPPYLLPLVQRDKLYNVKEICQKSMNGGKLAVGAGAGPHPLRSSNCEGIYNMSISS-DGQLKNGSYTAKVSGLEESCVLESIPDT--EPRCALLLNLFVCRGEPGSVIKITCKKRTGHLNFIECIRQGLLQKYGEKCVGMGGIFKINQGKAYQHVMR-DFSKTPINNEKELNQWLKFFEMPATLNALGVLITHENDLDLRLQHFHSFSTSNWGGHYHYDTTPETVEYEAYFNVAERIVRVDKPLETHKFGRD -> ---KKELDCPKLEDIQKVLLKALKNNFSEANVDVVDCPDLTAEPFCLASKGIGGSTAVVEVGGPPYLLPNVDKEKVYDIKDIVKAIGIKPCFVLGAGAGPWPFVGKNSEMMANVLIDG--DQVLSKTHVAKLKDDGKDINVSVLPPT--ETRFALMGNLFFSEGIQSKVLKVHCKNRIGVDNFITVLRKGLEDEFKDKYVGLGGAFLIKSGKALQHVMP-EFSSTPIYSEEELNKWLNFYEMSAPLVAVGTLMSSDVDFDLRVQHFHSFSEHGDAGHYHQDTTPNEVEYLGYFNVGQYIYRIDKPLHTHQFGRD -> -VEKLDLHPIPLQELSDAIKTGLAHQFESTSVSVEQCPDLQQTPYNLAFAGLCGSPRIADVGGQPNLAPTPDFSKKYDLLDIARLMELPKEALLGAAAGPFHVVGTNSELMPILQWNG--AEVVNQTHFAKVKDDG-SALCEKL--A--SHDCALMANLFGCEGLPGDVLHITASSRTGSLNFTEAIRRSLEDAYGQKTISLGGVFLISKGKAKLHIMP-DFSFVPLITDEQKQKWLKFYETEAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPKDVQYEAWFNVAKILYRIDRP--------- -> ----IETLKPSNEELLAIFEGALKENFKDVEIKLCQCPDLTAEPYNMTSTGFGRKMVIAEVGGPGNLFPVIHKEKDFDLKEICNGCEAPASFVFGPGAGPWQVVGRNCEMVADANFSSS----KVATKIASLPPGHTAYKMEVI--S--SPKFSLMANLAVSAEGPAQVVYCKASVRTGKDNFPETIRKGLAKHYGDKCVSVAGVFMMLKGEAKLHVMP-DFPGCNFSSREELKQWLRFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSSHGDAGHYHYDTTPDTVVYEGYFTAAEKIYRFDE---------- -> --TSRTLHQPPLDELMNVLAGGLTANFEEATIDLADCPNFSRRPYNFFREGLCGNPIIFEIGSPAYLLPTVQRDKIYDIKTLLQHINYNHDLVIGAGAGPWPRTGCNCELIMKLNLKLDNFQVQNGTHYAFVDENNGRCRLQRLADNDTESTFALLGNLYACEGKPGKVIKVRAKKRTGKLDFISCMQKALEKHYENKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTSEIHLNNWLRFYDMPTPLIAVGTFVSAETDLDLRVQHFHSAFELGLGGHYHIDTTPDTIEYEGYFNVAATLYRVDQPPNKLQFGKD -> ---TRALHVPPLEEIRDILREALPANFAEVTIDVVDCPDLTQQPFSLAEPGLGGGTKLLEIGGIPYLFPHVHRDKVYDIKSILQNVDHSGKFIIGAGVGPWPLVKSNCELMMNMSISPTESSTKNATHICMVDKGDGKCVDKTLSAS--ETRFSLSANLFLSEGKPGKVIKVHVKKRSGSNDFIGSIRAALAARYTEQVVCLGGAFLLKEGKAKLHIMS-DFTEAPLISYDDLKKWLNFFEMSAPLVALGTLVTASTDLDLLVEHFHTFSDHGEGGHFHFDTTPDTAEYVGYFNVIETVYRVDQPP-------- -> ---KIILNAPSLEELRPILENALKKNFEQVSVDIVECPNFKAPPFSMSGAGIGNDLRIGEIGGIGNLYPSPRTDKVFDLKEICVTCEIPEAFIFGPGAGPFHVVGHNCEMVADANFIE--RQNNVATKIAEITASGKGYRMSTI--D--KTGFALMANLAISDGRPGKVLRIRATKRNGEMNYPESIRKALTAHYGETLVSLAGVFVLKKGKVHMHVMP-DFPGCPWKTHEQVNEWLKYFEMNAPLVCTSVLHSNDVGGKLRLEHTHCFSEHGDAGHYHYDTTPNDVDYDGYFAPANVIYRIDM---------- -> --EEKPLYVPSLEELQSVIQGALDKNFATASVNVGTCPDLKAPQFGLVESGLGGKPILLEVGGPPYLLPLVQREKLYNIKEITRRAQGAQGFAIGAGAGPFPIRNSNCEGIYNLSVSA-ENELNNGSYTATVRGEHEECVLERIPST--EPRCALLLNLFVCSGETGPVLKISAKRRKGEFNFVECIRKGLEKHYDDQVVGLGGIFLVKSGAVHQHVMR-DFSTTPIHTDEEVNQWLKFYEMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDSVEYEAYLNVAERVVRVDPPADTHKVGRD -> ---KLQLHVPRLVELAEIIQAGLAENFATVHVNVVDCPNLTEEPFFLAAKGLGGSPRIADVGGNGNLYPDVRKDKLYNMRQVCETSNLPHAFAIGPGAGPLHLLGCNSEMVHNVHFVD-DKHSIFKSYVIFLNQSSEPYTVKML-DNKFANEFTLMANLLLTEGKTDKVLKIVAKKRIGEENFVTCMRLALAKKYGDKPVGLGGVFVIKSGKAKLHIMP-ELPEKFSNTDEILNNWLKYFEMSAPLVCTGVFISHDPGLDLRPEHTHCFSDQKHGGHYHYDTTADEIEYEGYFTPAESLYRIDRP--------- -> --EEKPLHTPSLVELRDVLAVGLKSCFATVNVEVVECPDLSKAPFHLAGCGLNGNPALVEIGGPPYLLPTVDRTKLYDIVPIAKRALHDDQIAIGAGAGPFPLVNSNCEGMFNLHYSP-PGKVVSESHLAMVTPER-EVIVRKIPNT--ETRCALLGNLLVSEGNAGPVLKVSCKRRTGNKDFIASIRTCLEDRYGEKTVGMGGVFLLQAGKAKQHVMS-PFSTSPIHTEEQLNEWLNFYDMPAPLVNLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVAGERIVRVDKPVHTHKFGRD -> --EEKPLHVPPLSELQNVIQGALSGNFAQVEVSVGACPDLKAARFGLVESGLGGRPTLLEAGGPPFLLPLVQRNKLYNIKEITRKIQGPGKFAVGAGAGPWPIRSSNCEGIFNLSVSE-SGELTNGSYTATVRGEQEECVLEKIPHT--EPRCALLLNLFLSQGAPGQVLKISAKQRTGEQNFIECIRKGLEEHYGDQVVGLGGIFLIKKGAAHQHVMR-DFSKTPIHTDEEVNEWLKFYEMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLSTHKVGRD -> --ESVALHMPSLDELAEVISVGLRKNYKESSCSVVDCPDLSKEPFGLAANGICGRTKLVEVGGVPNLVPLSKMEKVYNLQTISERIGAPGCFVLGAGAGSKHVVGCNCEMMPNFRCRGGEKERVNLTHIAKVKQDG-GYLLQNYENDYASSEFTLLANLFCSDGNPGKVLEVHAKSRIGDKDLVGCIRGALKEYFGRRPIGMGGTFLVKDGRIKIHVMP-DFSETPLTSEEDVNNWLRFYEVNAPFTCLSTFITEDCGLDLRLEHTHGYNTNGVGGHYHYDTTPEEVEYLGYFSPAEFIFRVDRPTETHQIGRD -> --EEKPLHMPTLQELRDVLADGLKSCFTTVDVEVVECPDLTRAPFHLAGGGLCGSATLVEIGGPPYLLPTVDRSKLYDVIEVSKRA-LPKSISIGAGAGPFPLVDSNCEGIFNVRHSP-PGTIVSESHLAIVAPETGKMSIRKIPNT--ETRCALLANLLVSEGRPGPVLKVSCKRRTGNKDFIASIRTCLADRYGEQTVGLGGVFLLVAGKAKQHVMS-PFSTTPIHTEEQLNEWLNFYDMPAPLINLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPDTVEYEGYFVVGERIVRVDKPLITHKFGRD -> --EEKPLYVPPLQELKEIIQSALTKNFENVSVEVGDCPDLTDPFYGLLSSGLGGSPVLLEVGGPPFLLPLVQRSKVYNVKEIVQKA-LPGKLAIGAGAGPFPLRNTNCEGIFNMAIDE-QGNLKNGSYTAKVHGAEEVCVLERIPDS--DPRCALLLNLYISRGAPGPVVKVKCSKRTGEQNFVECVRKGLESHYKDKCVGMGGIFVLKKGAAHQHVMR-DFSKTPLHSEEELNNWLKFYNMPAQLNAVGTLLTNEHGLDLRLQHFHSFSKSNWGGHYHHDTTPDEAEYEAYLNVAERVVRVDRPLESHKIGRD -> --EEKSLHKPPLEELQNVLQSILTRNFENVTVNVSQCPNLNAPEYGLMDVGLGGCPTLLELGGAPYLLPKVQKDKLYDIKAICRKSMGEGKLAVGAGAGPYPLRTTNCEGIFNLSISA-QDEIKNGSYTAKITGLQEDCLLEPIPDT--ETRCALLLNLYVCRGEPGPVLKITCKKRTGHMNFIECIRKGLYEKYQDKCVGLGGLFLLKNGKAHQHVMR-DFSRSPIHTESELNQWLKFFEMPGTLHAVGTLVTHEHDLDLRLQHFHSFSRTKWGGHYHYDTTPDTIEYEAYFNVAERIVRVDKPKTTHKFGRD -> --EEKPLHTPSLTELRDVLAAGLGSCFATVSVEVVECPDLSKAPFHLAGSGLNGTPALIEIGGPPYLLPVVDRTKLYDLVSVTKRALHGEEIVIGAGAGPFPLVSSNCEGMFNLRYSP-PGTVVSESHLAMVTAER-EVVVRKIPNT--ETRCALLANLLVAEGNAGPVLKVSCTKRTGNKDFIASIRTCLDDRYGERTVGLGGVFLLREGKAKQHVMS-PFSTKPIHTEEQLNEWLNFYDMPAPLVNVGTLVTNECELDLRLQHFHSFSTHGHGGHYHIDTTPETVEYEGYFVAGERIVRVDKPVNTHKFGRD -> --EEKPLHVPPLSELQKVIQGALSENFRTVEVSVGSCPDLKASQFGLVESGLGGKATLLEAGGPPYLRPLVQRDKLYNLKEITRKAQGPGQFAVGPGAGPWPIRHSNCEGIFNFSLNE-KDELTQGSYTATVRGETEECVLERIPET--EPRCALILNLFLSEGKPGEVLRIFAKQRTGDENFVECIRKGLEKHYGDEVVGLGGIFVIKKGAAHQHVMR-DFSKTPIHTQEQIQNWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSFENWGGHYHYDTTPDKVEYEAYLNVAERVVRVDRPRVTDQLGRD -> --ENVALHVPSMEELAEVVGVGLKKNYKEWSCSVVDCPDLSKAPFGLASNGICGRTRLVDVGGVPNLVPVSQMEKVYNLQDISERVGTPGCFILGAGAGSKHVVGCNCELMPNFRCEGGERERVNLCHVARVKSDG-GYLLQNYENDGSSSEFSLLANLFCSDGKQGKVLEVRGKCRIGEKDLVGCMRGALKEHFGNRPIGMGGTFLVNKGKIKIHVMP-DFSETPLTSDNDVNNWLKFYEVTSPFMCLSTFITEDCGLDLRVEHTHGYNNSGVGGHYHYDVTPDEVEYIGYFTPAEFIYRVDRPSTTHNIGRD -> --EEKPLHVPTLEELQHVIQGALAGNFKTVSVSVGACPDLKAAQYGLVESGLGGKATLLEVGGPPYLLPLVQRDKLYNITEMTRKIQGAGKFAIGAGAGPYPIRSSNCEGIYNLSVSA-QNVLTNGSYTATVRGEQEECVLERIPSS--EPRCALLLNLYLCQGQPGPVLRINAKQRKGELNFIECIRKGLEQHYGDKVVGLGGIFVIKRGAAHQHVMR-DFSQTPIHTDEEVNEWLKFYEMPAQLNALGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLDTHKVGRD -> -IEEKELFQPPLKEVCDVFLSGLLKNFKNASVTIEECPDLTKEPWTLASNGICGTPYLLDVGGVPYLTPNPQFHKIYNYETIAKVLPFDNVLILGSGAGPFHKIGYNCELMANMYISK---VFKNESRIASIDKNG-SYELQI--NQ--EKEFGILGNFLASEGVPGKVIKVNASVRKGGKNFIECIRESLRAKYPDNMIGMGGVFVIKSGKAKIHVMP-DFSCSPLNTKEDVDNWLRFFEMSSPLVCLSVFYNIDQGMDLRIDHTHCFSHHGDGGHYHFDTTPDDVSYEGFFVLAEKVLRIDRP--------- -> -VEEKPFYQPPLQEVVDVLSAGLPSNFESVKVEVVDSPDFTKAPFDLTSPGISGNVKLIELGGPPFMLPTVQRDKVYELAGLARALGRENALVAGAGAGPWPWAGVNCEGIINLSIRD--GKVNQGTRVVTVDPPSSGYKLQRLPQN--ETRTALLGNFLISDGLPGKVIKVVAEKRIGESNFISAIRETLLKHYGDKVVGLAGTFLLLSGRAKHHVMP-DFPAEPIHTEAGVDRWLHYYDMPAPIFYVGTMVTGDLGLDLRLQHFHGYG-AGVGGHYHYDTTPGAARYEGYFTLAESVLRVDRPPVTHGLGRD -> --EEKQLYRPSLAELKEVIQSALVKNFENVTVEVTDCPDLKTAEYGLMDSGLGGSPTLLELGGPPYLLPLVQREKLYNVKEICQKT-MGGGLAVGAGAGPYPLRNSNCEGIYNMSISA-EGQLKNGSYTAKVSGLEESCVLESIPDT--EPRCALLLNLFVCRGEPGQVLKISCKKRTGHLNFIECIRQGLLEKYQDKCVGMGGMFKINQGKAHQHVMR-DFSRTPIVDEHELNQWLKFYEMPATLTALGTLITHENDLDLRLQHFHSFSNSNWGGHYHYDTTPEIVEYEAYLNVAERVVRVDKPKETHKFGRD -> --EEKPLHVPTLEELQQVIQGALRKNFATASVQVGDCPDLKAPQYGLVESGLGGRATLLEVGGPPHLLPLVQRDKLYNIKEIARRIQGAGKFAVGAGAGPYPIRSSNCEGIYNLSVSA-SDELTNGSYTATVRGEQEECVLERIPST--EARCALLLNLYLSRGEAGPVLKISAKQRKGELNFIECIRKGLEEHYGDRVVGLGGIFVIKKGAAHQHVMR-DFSKTPIHTDAEVNEWLKFYDMPAQLNALGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDTVEYEAYLNVAERVVRVDKPLATHKVGRD -> --KSRPLYQPSLEELVDVLEEGLRANFVEVTIGITDCPNFNEQPYNFHREGLCGNPIVFDIGDPAYLLPSAQRDKFYDVKSLLRHLNYNTTLVIGAGAGPWPRTGCNCELIMKMHLSP-RQEVENATRYAFVGKTNEECVLHQVPVNEDETTFALLGNLYVCEGRPGQVIGVRAKKRTGNLDFIACMQKALGSRYKDKLVGMGGTFVMRNGMIKQHVMR-DFSKTPLNSEAELNNWLRFYEMETPLTAVGTFVSAETDLDLRVQHFHSASDNKLGGHYHIDTTPDTIEYEGYFNVATIIHRVDQPANKLQFGKD -> -VEKKALHVPSLDELSAVLQHALQANFANASATPVECPDLTAAPYHLAAPGINGSPRLADVGGVPYLIPTANRNVLFDLQEVATKVDLPGAFFIGAGAGSWKYIGTNCELMPNVHLGAS----NNLTTTAIVAHD--KCELRPY--D--TTQVGVLCNVLASEGVRGPVVHVKASVRTGPKDFLSCLHQAIVSRYGQQGVGLGGVFVIREGKAKIHVMP-DFSPVPLCSDAEVDQWLKFYEMQSPLVCLSTMVSGDLGLDLRLTHTHCFSNHGEGGHYHYDTTPEVVEYEGYLVPAEHIYRIGRPQVTHKVGRD -> -VEKFAFHVPSLEELAGVLQKGLKENFADAQVSVVDCPDLTQEPFNFPAKGNLAFSTSADVSKGVRGVRVVL--QVYDLNTVAKDIELPGAFILGAGAVSSRVLGVNAELIPIVQTKNEKKPAVNGSYIAQINPADKGCLLEKYSSKYSDCEFGLLANLYASEGQPGKVIEVKVNGRTGELNFVSCLRQTLEKHYGEKPVGLGGTFIIQKGKAKIHIMPPEFSACPLNTDEDVNNWLKFFEMKAPLICQPVIVSRDPGFDLRLEHTHCFSQHGEGGHYHADTTPEAAQYRGYLLPAELLFRIDRPKATHRVGRD -> --EEKPLHVPCLSEIQRVIQGALSENFKTVDVSVGPCPDLEEPQFGLVESGLGGNPTLLEAGGPPYLRPLVQREKLYNLKEITRKAQGSGEFAIGPGAGPWPIRNSNCEGIFNFSLSE-KDELKQGSYTATVRGDQEECVLERIPET--EARCALILNLFLSEGKPGEVLRISAKQRTGKENFVECIRKGLEQHFGDKVVGLGGIFVVKKGCVHQHVMR-DFSKTPIHTQEQIQEWLKFYEMPAQLNAVGTLVTKDLGLDLRLQHFHSFSFENWGGHYHYDTTPDVVEYEAYLNVAERVIRVDRPVVTDQLGRD -> --VKKPFHVPELRAVADVLNNGLKAHFSEVLVEVVDCPDLTQAPFHLANKGLNGNPNLLDIGGPSFLIPLVDRTKVYDLKDMAEISGNKPAFLIGAGAGPFNHLKTNCEGIFNINVGD---EIKQESRIGMLNRETGSPMELKLNNS--ITEFGLLGNLYSSQGKEGKVLKVHAVKRIGTIDFIASIRSVLSEAYKDGIVGLGGTFIIKKGSAKLHIMP-DFSDTPIEDDETLNKWLQFFNMSSPLVAVGTLVTGTYNMDLREQHFHMFSDHGNAGHYHIDTTPDVVEYLGYFNVANHIFRVDQPKTDAAFGKD -> --EEKPLHVPPLSELQKVIQGALCANFATAEVSVGSCPDLKAGQFGLVESGLGGKPTLLEAGGPPYLRPLVQRDKLYNLKEITRRSQGPGKFAVGPGAGPWPIRNSNCEGIFNFVVSE-KDELTNGSYTATVRGEQEECVLERIPDT--EPRCALILNLFLSEGKPGEVLKIRAKQRTGQENFVEYIRKALEQHYGDQVVGLGGIFLVKKGCVHQHVMR-DFSTTPIHTHEQIQQWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSASNWGGHYHYDTTPETVEYEAYLNVAERVVRVDRPVVTDQLGRD -> --ETKDLFVPDNKELKEALTLGLKKNFQEVSVDFVDCPDLSGEPFNLASSGLCGNPTILEYGGAPYLLPLVQRNKLYDLNEICQERNMKEYLAIGAGAGPYVFCNTNCEGIFNLAGRQPDGKIVSKSHLALVDKDK-QCERRNIPAS--ETRTALLGNIYLSEGKGGQVLKINCKKRTGTNNFITQIRESLSDHFEGKDIGLGGTFLLKSGKAHQHVMQ-DFSQTPIYTEDEINTWLKFYDMPAPLVAVGTLVTNEMDLDLRLQHFHSFSPSHWGGHYHYDTTPDTVEYEGYFGIGEKLFRIDKPEETHKFGRD -> -IEEKPLHVPPLEEIQKVIQGALCANFKTVEVEVCPCPDLKAKPFCLVESGLCGCPTLLEVGSPKFLIPMVQRDKLYNIPEIIRKVQGPGRFAVGAGAGPWPFFNSNCEGIFNMSVDK-DDKLTNGSYTATVRGENEECVLEKLPDT--EPRCALLLNLFLSQGLPGKVIGIHAKKRICEKNFVECIRIGLDEHHGDKVVGLGGIFVMKRGCANQHVMR-DFSKTPLNSEEDVEKWLKFYEMPAQLNCLGTMVTKDLDLDLRLEHFHSFSFSNWGGHYHYDTTPDSVEYEAYLNVAERVLRVDRPV-------- -> ----IDNHVPSLEELKMVFQTSLLSNFENVEVNIVDCPDLSKPPFNQKSSGFGHNLRIAEVGGPGNLYPGFHIDHQFDIPKIGKVCEHPEAAVFGPGAGPWPIVGQNCEMVADVNLKT----GEVGTRIAEINSNSDKRYVQRI-ID--EPKFSLMANLALSDAKSSTVVHFKASVRKGEKNLTNCIRDGLQEHFGKKIVSLAGQFIIQTGKARLHVMP-DFPGCPFENNAEVDKWLNYFEMSAPLICATVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEIK-------- -> -IEEKPLHVPPLSEIQKVLQGALCENFKTVKVKVCPCPDLKAKPFCLVESGLCGNGTLLEVGSPSYLRPLVQRDKLYNIPEIIRRVQGPGRFAVGAGAGPWPIRNSNCEGIFNLSVDK-DDQLTNGSYTATVRGESEECVQEKLPDT--EPRCALLLNLFLSQGLPGEVIGILVKQRICEKNFVDCIRKGLLEHYCDRVVGLGGIFVIKRGCVHQHVMR-DFSKTPLESEEDVNKWLKFYEMPAQLNCLGTLVTKDLDLDLRLEHFHSFSFSNWGGHYHYDTTPDSVEYEAYLNVAERVLRVDRPV-------- -> --EEKPLYVPPLQELKGVIQSALAKNFENVSVEVGDCPDLKDSFYGLVDSGLGGSPLLLEIGGPPFLLPLVQRSKVYNVKEIVQKA-LPGVLAIGAGAGPFPLRNSNCEGIFNMAIDE-DGNLKNGSYTAKVHGAEEICVLERIPDT--DPRCALLLNLYISRGAPGPVVKVKCNKRIGELNFVECIRKGLESHYKEQCVGMGGIFVLKKGAAHQHVMR-DFSKTPLQTEDELNEWLKFYDMPAQLNAVGTLITHEHDLDLRLQHFHSFSKSNWGGHYHYDTTPDVAEYEAYLNVAERVVRVDRPLETHKVGRD -> --ESVRLFTSPLEDICSILRKGLEKNFKEVSVSVEECPDLTKAPFNLPAAGLAGSTRIADVGGPPYLVPFADLSKNYDFNELAKLIDLPDSFIVGAGGGPHEIVGMNSEMMPNLRTGT---NADNNSKVSKLSGDG--HELVSLAKD--QACCSLMVNLFACEGAPGKVLKVRARQRIGEENFVSCIRKAITEGFPNKVVGLGGIFRMLSGAAKCHIMP-NFSKIALNNDEEVSNWLKYFEMAAPMIFFSVMVSSDPGLDLRLEHSHGYG-AEYGGHYHYDVTPDTVEYEAYYNLAEVLYRVDKPQNTHNIGK- -> --EKRDLFTPSLKDVATELNNRLTLYFKTVDVDVVECPDLHQPPYCFAARGLCGQPMLVEVGGPTYLIPKVDRSKVYDFCDIQRVLNINPCYFMGAGAGPFPYTEVNCEGIYNVMIDG--SVVKQRSKISKINVNNGTSEQQDLPNT--ETRFALLANLFVSQGLPGEVLKIHVKERIGCHDFIASIRNCLKDAYSTAVVGLGGVFLMKSGTFRQHVMP-DFATDEIKSEEQLNGWLRFYNMSAPLVAVGTLVTGDMDLDLRLQHFHSSSDHNEAGHYHNDITPETVEYLAYFNIANSVVRIDKPKDSHDMGRD -> --ESKDLFIPDNKELKEALTIGLKKNFQEVSVDFVECPDLSGAPFNLANSGLCGNATIVEYGGAPYLLPLVQRDKLYDINEICLKICRERQLAVGAGAGPYVLCNSNCEGIFNLAGGL-DGKIVSKSHLALVDKDK-QCERRNIPAS--ETRTALLGNIYLSEGKTGQVLKIHCKKRTGSNNFITQIRESLASHFVDKDIGLGGTFLLKSGKAHQHVMQ-DFSVTPIYTEEELNTWLKFYDMPAPLVAVGTLVTNEMDLDLRLQHFHSFSPSHWGGHYHYDTTPDTVEYEGYFGIGEKLYRIDKPKETHKFGRD -> ---KIVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADADFTT-DHQNNVATKVSRVVPNGKGYEMSTI--D--NADFVLMANLAISDGFPGKVLRVHAAKRNGEMNYPGAIRKALIGYYGNSLISLAGVFLVKKGKVRMHVMP-DFPGCPWETIEEMKEWLKYFEMKAPLVCASVLHSNDIGGKLRLEHTHCYSEHGDAGHYHYDTTPDEVEYEGYFAPAKFIYRIDM---------- -> --EEKPLHVPPLLELQKVIQGALNANFASVDVNVGPCPDLKDSQFGLVESGLGGRPTLLEAGGPPYLRPLVQREKLYNLKEITRKVQGPGKFAVGPGAGPWPIRNSNCEGIFNFSLNE-EDELKQGSYTATVRGEKEECVLERIPEN--EPRCALILNLFLSEGKPGEVLRISAKQRTGVENFVDCIRKRLEQHYGDKAIGLGGIFVVKKGCVHQHVMR-DFSKTPIHTQEQIQQWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSFANWGGHYHYDTTPDIVEYEAYLNVAERVIRVDRPQLTDQLGRD -> -VEEKPLYCPSMNDVAQALKDGLSENFETVEVSVVDCPDLTQKPFSLASQGLGGSPTILEVGGVPFLMPLVNRSKIYDFKDMNKVTGVNPAFIIGAGAGPFTYAGVNSELVANLVVKD--GEVRQLSQIAKLKDESNEFITETLQDS--VTSFALLANLFVSEGKPGKVLRVHCAKRKGKSDFVTAARDSLLKGFPGKAIGVGGTFLINGSKVKQHIMA-DFTTTPLDTEEKVNNWLRFYSMNPPLVALGTFVTNDPGLNLRVIHFHALSDHGEAGHYHYDTEPEKVEYLAYFNLGTKVVRMDRPQDESKLGH- -> --EEKPLHVPTFEEVQEVLLKELPTNFAEVSVEVVDCPNLSNPPFHLVKPGLNGSPTLIEVGGAPYLLPLVDRSKVYDIEKVARKAVGKDVLAIGAGAGPYMLPGVNCEGIYNVNVKR-DGTLESGSYYSYVKGTEESCQAVKIPHN--EARFALLANIFASEGNPGKVLRVYCKTRTGNQNYIESIRLALAKKYPEQCVGLGGAFLLKSGAAKQHVMR-DFSTTPIHTEEELNTWLKFYNMPAPLVAVGTLVTNEYDLDLRLQHFHSFSKSHWAGHYHIDTTPDYVEYEGYFTFGEKIVRVDKPVNTHKFGRD -> --EERPLHVPPLSELKRVIQGALDENFQTVDVSVEACPDLRDSQFGLVESGLSGKATLLEAGGPPYLRPLVQRDKLYNLKEITRRAQGAGKFAVGPGAGPWPIRHSNCEGIFNFSLNE-EDELTQGSYTATVRGANEDCVLERIPET--EPRAALILNLFLSEGKPGEVLRISAKQRTGGENFVECIRKGLERHYGDQVVGLGGIFVVRRGCVHQHVMR-DFSKTPIHTQEQIQNWLKFYEMPAQLNAVGTLVTKDMGLDLRLQHFHSFSFANWGGHYHYDTTPDTVEYEAYLNVAERVIRVDRPVATDQLGRD -> ---VIENYVPSLEELKEVFQSSLKLNFETVEVDIVNCPDLSKSPFHQTSSGFGQNLRIAEVGGPGNLYPGFHINHQFDIKTIGKVCEHPEASVFGPGAGPWPVVRQNCEMVADVNLKT----GRVGTRIAEIDTKNEKLYVQRT-ID--VPKFSLMANLALSDAKSSKVVHFKASGRTGQKNVTNCIRDGLQEHFGEKVVSLAGQFIIHSGQAKLHVMP-HFPGCPFENNEEVDKWLNYFTMSAPLVCSTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPDSVSYEGWFAPANRIYRIDEVA-------- -> -VEEKSLAQPPLNLIAKAINDGLTKDFEYVQAEVVDCPDLTKAPFHLAAEGLGGSETIVEFGGVPYLMPLVQRDKVYDLKDLIQIIGIDPVFVVGAGAGPHVYVQKNSELVTNISISK--NNIINLSRIAKLKDEQNDFEVEIL-K--EETRCSLLANLYTCQGKSSKVLKIHCKKRIGKNDFVSAVKQTLASTFKDQCIGMGGTFLITGSKAKQHVMP-DFSKTPILNDDQVNEWLRFYEMGPPLVAVGTFVTKDPGLDLRLQHFHSFGTHPEAGHYHIDTNPDTVEYLAYLNTGSKVVRIDRPHETHQVGRD -> ---RIDLTVPSLDRIIEALLPELSKNFETVSVDAVQCPDLTCSPFNLAAEGLNGDEMVIDIGSPSFLLPLVNLDKVYDIRDFMKVTGTDPLFVMGAGAGPWPHVGVNCEFIGNVRLTSD-DSVNNCSHLYKVDPQTGSQVHHRLPQD--ETRFALLANFYTSRGMKGEVLKIVCETRNGPLDFVTSIRQALAKYFGDKPVGLGGVILIETSKVKVHVMP-DFSKTPLHSETDLNNWLKFFEVSTPLVALGYLVSHDPGLDLRPQHFHMFGTHGEGGHYHHDTEPTTVKYTAYFNVAKKLIRVDQPEIALLFGK- -> --EKRILHLPPLQEVAEVLQAGLRQNFAEVEVVAVDCPDLRE--WGIAGEGLGGNTRLLDVGGPPFLIPTVMREKLYDMRDYPQLTGLSEGMMIGAGAGPWPYINRNSEMMPNLFVKQ-DKTIIQRTHITRTNDEDGSYETLKLPES--ETRNAVLGNLFLCSGEPGKVLKVHCKVRTGEKNFVTCMREVLNAYYGELTVGMGGVFKILQGKVWIHVMP-DFSPCPINTDEDLNNWLKFYEMSSPFTVLSTLISRDPELDLRVEHGHGWGENSQGGHYHYDTTPEEVEYLGYYNLAELCYRVDKPTNTHQLGRD -> ----AILHQPALQEVAGVLEKGLKENFKTVKVEVVDCPDLRD--WGVAGEGLGGSTRLLDIGGVPFLMPTVMRDKLYDMKDYPTLTGLTEGLVIGAGAGPWPFINRNSEMMPNLYVNK-DKSLIQRTHITRTKDEDGSYETLDLPDS--ETRNAVLGNIFISEGKPGKVLKISCSARTGPKNYVTCMREVLGDHYGEKAVGLGGVFKVLQGKIKVHVMP-DFSACPITTDEEVNQWLKFYEINAPFTVLSTLISRDPGLDLRVEHSHGWGEAGTGGHYHYDTTPDQVEYLGYYNTADLCYRVDKPTQTHMIGRD -> --SKHTLNPPPLEDIATKLQSALAKNYRDSSVVVERCPDLRHAPFHLATQGLSGNERVADVGGQANLFPKPHLECKYSLLDIAKAMEMDLESLVGAGAGPSHIVGQNCELAPNLAWEGGFEKVENRTYVAKIAKDSGEAIVDKC--S--STDCALMVNLFGSSGLPGPVLKITARGRQGSGSFPECIRTALHAAYGAQPVSLGGVFLVKSGKARYHIMP-DFPSAPFENRDDVEEWLTFHNFNAPMVCLTVMHSADPGLGLRMEHTHCFAPRDAGGHYHNDVESEEIEYEAYFNTAKVIYRIDPP--------- -> --ESKPLFVPPLNEVAKALQDGLSKNFINAEVNAVDCPDLSNAPFNLAAKGMGGKERILDIGGVPYLIPLAQKHKLYDMRDYPSLTEMNEALIIGAGAAPFTYIQRNAEMMPNLTVDHEGKVKTQKTTMARTDDEEETYKLLHLPKE--ESKMSLLGNLFLSEEKPSQVLEIKCRCRSGKQNFVSCISNILRETYPEKCIGLGGVFCAAKGKLKIHVMP-KFSEVPLQTDKDVENWLNFYEMDAPFTCLSVLVSNDPGLDLRLEHSHGFNAQGQGGHYHYDTTPDVIEYTAYYNIAEACYRVDRPNVTHMVGRD -> ---RLETHVPSLEAIADAFRSKLPSNFETVTVDIVECPDLSSAPFNLTSPGFGKNLVIAEVGGPGNLFPTIHKEKAFDITKICSTCEQPRAFAFGPGAGPWPIVGVNCEMVADVNCADN----KVGTRTAKIEGDS--YKVEQI--D--SSTFSLMANLAVSEPQGGRVVHIKAKRRTGKTNFPDSLRQSIVKAFDGKLVSLGGFFVLHSGRAKLHVMP-DFPGC-FETEEEVSQWLRYFEMNAPLVCATVMHSNEGGHKLRVEHTHCYSAHGDGGHYHYDTTPDEVEYEGWFAPASAVYRIDE---------- -> ---VIENYVPSLEELKEVFQKSLDANFETVQVDIVDCPNLSDPPFHQTSSGFGQNLKIAEVGGPGNLYPGFHTDHQFDIRTIGKVCEHPEASVFGPGAGPWPVVKKNCEMVADVNLKT----GKTATKIAEIDENSSEKKYRQKTIE--EPKFSLMANLALSDAKSAKVVHFKASVRTGEKNVTHCIREGLQEHFGERPVSLAGQFIIHTGQAKLHVMP-DFPGCPFANNEEVDKWLNYFTMDAPLVCATVMHSYDPGHNLRLEHTHCYSEHGDAGHYHYDVTPATVAYEGWFAPAGKVYRIDEVA-------- -> -VEEKPLFFPPLENVAEALKVGLSENFETVEVSVVDCPDLTQKPFSLASQGLNGSTTILEVGGVPFLMPLVDRSKVYDFKDMNQVTGVNPAFIVGAGAGPFRHAGVNCELVANLVVKD--GQVSSMSQIAKLKDESNEFVTETLQDS--VSTFALLANLFVSEGKPGKVLRVHCAKRKGKADFVTAARESLLKGFPGKSIGVGGTFLVSGSKVKQHIMA-DFTSTPLDSEEKVDNWLRFYSMSPPLVGLGTFVTNDPGLNLRVIHFHSLSDHGEAGHYHYDTEPEKVEYLAYFNLGAKVVRVDRPQDESKLGH- -> -VKKLALNPPPLSELSQVIGERLSKYFGHVATNIIPCPDLRQPPFHLAGKGLCGNERIADVGGPPHLRPSPRLDKKYSLPSIMQMIEMQQPFVLGAAAGPFHVIGQNSELMPNLARGE-DGEWQNETHYAKVNEDG-QCHLDKVPDD--SKDFGLMANLFASDGLPGDVIHIRAKRRIGDLNFTEAIQDAVKTEYGERPISLGGVFLVRSGTTKLHVMT-DFSPDPCPGPD--HEWFKYYDSSAPLICLTVFHSADSESDLRMEHTHCFSKHGMGGHYHYDTTAEEVEYEAWLNPAKVMYRIDQPG-------- -> ------------------LANGLKSCFATVNVEVVECPDLSKAPFHLAGSGLNGSPVLVEIGGPPYLLPLVDRTKLYDVVSVAKRALHDDRVVLGAGAGPFPLVGSNCEGMYNLRYTP-PGTVVSESHLAMVTSEQ-EVVVRKIPST--DTRCALLANLLVAEGNAGPVLKVSCKRRTGNKDFIASIRTCLDERYGEQTVGLGGVFLLQAGKAKQHVMS-PFSNAPIHTEEQLNEWLNFYDMPAPLINVGTLVTNECELDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVAGERIVRVDKPVNTHKFGRD -> ----YSLEVPSLEDLVDVFRIALEANFRNVAVRIVDCPDLTEPPYGMAAKGISKSTKISDVGGVRYLTPLPQLDHKYDLQTIAKESELSPPFIMGAGCGPYQDVGCNCELMANVAVSS-AGVVKNESRIAKLDKDG-KCQIERL--Q--TTNLAILGNFFLSAGEPGKVVEIRAEGRTGSENFVSILRQAVRARYQEKPVGIGGVFLVEKGSLNIHVMP-DFSKAPLETEGTVDQWLKYFTQPAPMVFMSVFVSEDPGWDLRCEHTHGYGVQNRGGHYHYDTTPDEVEYVGYFGCAETLYRIDRPPS------- -> ---VAEMHVPPLDELAKVVSDGLTAHFKGVVAEVVESPDFREPPFHLAAEGINGSPRLADVGGPPYLVPKVQRHKVYNLTDIADEIKLPGCSFLGAGAGSSRLAGCNCELMPNSNLAT----GEIHTHFAKMKDG--APVLERY--M--SNEFGLLANLLATEGKAGKVLKVSASGRAGDLNFITAIRKVMHAHYGDKPVALGGVFIMDKGQAKLHVMP-DFSETPLTTDEEVENWLHFYHADAPLICLGSCVSHDPGFDLRVEHTHVFSSHGQGGHYHYDVTPVDVEYTGYFVVAEQVVRVDAPKETHQVGRD -> --TKHQISPPSLDELVGVLTPALQSNFETAKVSVERCPDLRYPPYHLAAPGLSGDECVADIGGQPNLFPEPRLECKYSLIEIAKEMDMDPDHLLGAGAGPFHRIGLNSELAPNLSWGNNFEQVVNQTYYTKIDDSNRAAVCERS--P--TTDCALMMNLYGSSGLPGNVIKITARARTGNKSFTECIRKTLAENYGDRPISMGGIFLIKTGKAHFHVMP-DFPPKPFKNAKQLNEWLTYHDFEAPIVCLTVFHSADPGKGLRMEHTHCFSTHNRGGHYHYDLPVGEIEYEAYFNTAKTIYRIDKPEVTLE---- -> -----------------VLQDGLTKNFSHATVTVVECPDFRQPPWNFPATG--KNLLIVDVGGPAYLLPLPQLNKIYDMNDVAAKADLPGGYVIGAGAGSHTSVGVNCEMIANVCTGTETSNPVIQSKITKVNPEDGSCVFQDY--D--VCDFSLLANCLITEGKPGKVLKVEASKRTGDENFVTCMRLALGSYYGNRAVGIGGTFMIAKGKANFHIMP-EFSKTPLNSPEEVNNWLKFYDMSAPLVCLGVLESYDPGLDLRVEHFHGYNNHGEGGHYHYDTTPNEVEYVGYFTPAERLYRMDRPPK------- -> --SKYTLTPPPLEDLATRLQSALAKNYGHSSVTVSQCPDLRLPPFYLATQGLSSNECIADVGGQANLFPKPRLECKYSLLEIAKAMEMGPESLIGAGAGPFHVVGQNCELAPTLSWKGSFENIENRTYVAKIAKDSGEAIVSKY--P--STDCALMVNLFGSSGLPGPVLKITARGRQGSGSFPKCIRTALHEAYGSKPVSLGGVFLVKSGKARYHIMP-DFPSKPFGSRDDVEDWLAYHTFAAPMVCLTVMHSADPGLGLRMEHTHCFAPRNAGGHYHNDVESEEIEYEAYFNTAKAIYRIDAP--------- -> ---RMDLNVPSLDRIIEALLPELSKNFETVSVDTVQCPNLTCPPFNLAAEGLNGDETVIDIGSPSFLLPLVNLNKVYDIRDFTKITKTDPLFVIGAGAGPWPHAGVNCEFIGNVQLTSKNNVNNNCSHLYKVDLQTENQVHNRLPQD--EMRFTLLANFFTSHGFKGEVLRIVCETRNGPLDFVTSIRLALAKYFGNKPVGLGGVILIETSKVKVHVMR-DFSKTPLHSETDLNNWLKFFEVDTPLVGVGYLVSHDPDLDLRPQHFHLFSNHGVGGHYHYDTEPTTVKYTAYLNVAKKLIRIDQPEIAPLFGK- -> -VEEKPLDIPSLKNIAEALQEGLSKNFVNVEVSVEDCPDLTKAPFLLAEKGLGGSPTIVEVGRVPYLMPLVNRSKIYDFKDMNLLTGVDPAFIIGAGAGPFLHATVNCELIANVVVKDN-QLSIQKTQIAKLKDESNEFVAEKLPDS--ESTYALMGNLFVSKGETGQVVKVKVSKRKGKSDFVSAARDSLVGGFPGKSIGVGGVFLTTNSKVKLHIMP-DFSKTALETEDQINSWLRFYEMNPPLVSVGTFVTNDPGLNLRLIHFHTFSEHGHAGHYHYDLDPDNVEYLAYFNLGAKVVRIDRPLEESKLGH- -> ---RSTLFTPTLDVLAIALKDGLNLNFKDVEVNVVTCPDLRNEPFDLASEGLGGKPRLLDIGGVPYLVPLAQKNKLYELKDVPKMTDFADCLIMGAGAAPWTHLKRNAEGMYNLLLKG-DGSIVQKTHIARTHDEDDRCELLALPET--ETKLSLLGNLFLSNGAKGPVLEVRCKGRSGPENFVSQMRKTLADAFPSKSVGLGGIFCVQKGQVKIHVMP-EYSEKPLKSDADVENWLKFYKMDAPYTCLSFLVSRDPGLDLRIEHTHGQNEKCQGGHYHCDTTAETVEYHGYFSLAEYVYRVDRPKVTHQIGRD -> --TQHKLSPPSLSELAEVITPALEANFSEAKVSVSPCPDLRQAPYYLATEGLSGNEKVADIGGQPNLFPEPRLECKYDMLQIAQEMQMESKQLLGAGAGPFHHVGVNSELAPNLSWQDNFDNVKNLTYYTKFDGAEG--KHAAICAPSPSCDCALMMNLYGSNGAPGDVLKVTARSRKGEKSFTECIRRALAEKYGERPISIGGMFLLKKGKAHFHVMP-GFEAKPFPDAKQLNDWLTYHDFEAPIVCLSVFHSADPGKGLRMEHTHCFTTSNRGGHYHYDLPPGEVEYEAYFNTAKTLYRIDKPEVTLE---- -> -ITKHHLSPPSLAELADVLTPALQANFEHAHVQVEPCPDLRKPPYHLATEGLCGGETVADIGGQPNLFPEPRLDCKYSLLDIAKAMDMSPHQLLGAGAGPFHRIGVNSELSPNLSWEGSFENVKNLTYYTKYDGTNHAASCERS--P--TSDCAFMMNLFGSSGLPGDVLKITARARKGEKSFTECIRRTLAETYGAQPISMGGMFLIKQGHAYFHVMP-DFPAKPFKDAKQLNEWLTYHTFEAPIVCLTVFHSADPGKDLRMEHTHCFSEGDRGGHYHYDLPPGEIEYEAYFNTAKTLYRIDKPDV------- -> --DKHSLHRPSLEEVAKALSDGLRSNFEHVQVDVVDCPDLRQKPFMLASEGICGQPRLTDIGGVPYLVPIAQTDKVR-VDLSLQDPERKHLSYFFLSAGKMHTVSVHLRQIYLCIYQSTGKPFFFIYWCNSFV-QDGSCVLGNLSGP--CCEFCLMGNFLISEGKQGKVIKVSAKKRTGQENFVTAMRNGLKAKYGTEPVGMGGAFLLAQGKAKLHIMP-KFSTAPLLTDAAMNQWLKFFEMNAPLVCLSTFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPDEVEYLGYFNVAEWLYRIDAPVSTHKIGRD -> -VKKVPLCPPSLSALAESISVGLSSNFTHSSCTVSTPPDLSLPPYHLASPGLTGSPRVVDVGGPPNLSPAPDLTKKYDLLSIAQQAEMSTAFMLGAGAGPFHVVGQNSELMPNLAYGASLHDVRNRTHYAKIKPDD-SVCCARIPDS--STAFALMCNLFCSDGSPGPCLHVTGKARNGPLNFTQAMQDALKASFGNRLISIGGVFLIKKGAAKLHVMP-DFPSEPFKSRDDVDKWLRYFDMHGPLVCLTVFHSGDDGGALRMEHTHCFTVTTKGGHYHYDLDDTEIEYEGWFNVAEYLYRLDQPG-------- -> -VKKVALSPPSLASLAEAIASGLSSNFAVSSCSMATPPDLTAAPYHLAGPGLGGSTRIVDVGGPPNLAPSPNLTKKYDLAAIARQVDMSPSFLLGAGAGPFYVLGQNSELMPNFAYGTAADSVRNRTHYAKITAAD-TVCCAPIPQE--STGFAFMCNLFCSDGVPCECLHVTARSRSGPLNFTATIQHALQAAFGDKLISLGGVFLINKGTAKLHVMP-DFPTQPFTSRADVDRWLRYFDMEPPLVCLSVLHSGHDGLALRMEHTHCFTVTTKGGHYHYDLDETEIEYEGWFNVAELLYRVDQPG-------- -> --TKYPLSPPSLEELADNLQAPLAANYEHSSVSIVQCPDLRQAPFHLASEGLSGNEKIADIGGQGHLFPRPLLDRIYTMDKIAEAMDMSPSSLIGAGAGPFHRVGRNCELSPNISWKQGYENVDNKTCFAQISPNTGDVSIKKS--P--SLECALMANLYGSESEPGPVIKITARKRRGQRSFTECIRKALVAAFGLKTISLGGAFLIKTGKARYHVMP-DFPPDPFKDSRQLNDWLTYHDFDGPIVCMTVLHSSDPGKGLRMEHTHGYSPGDCGGHYHYDVDGDNIEYEGYFNTAKAIYRIDMPSVR------ -> -VKKVPLFPPSLSTLAESISAGLSSNFRHSSCTVSTPPDLTLPPYHLAAPGLTGSPRIVDIGGPPNLSPAPDLTKKYDLLSVAHQAEMSTSFMLGAGAGPFHVVGQNSELMPNFAYGTDLRDVRNRTHYAKIKPDE-SVCCARIPND--STAFALMCNLFCSDGLPGPCLHVTSKSRNGPLNFTQTIQGALKSSFGDRLISIGGVFLIKRGTAKLHVMP-DFPSEPFKSRDDVDKWLRYFDMHGPLVCLTVLHSGDDGLALRMEHTHCFTVTTKGGHYHYDLDDTEIEYEGWFNVARYLYRLDQPG-------- -> --KNLALNPPPLSELGQVIGERLSRHFGHVVANVVPCPDLRQPPFHLAGEGLCGNERIADIGGPPHLRPSPRLDKKYSLPNIMGVIETGQQFVLGAAAGPFHIIGQNSELMPNLARGP-DGEWQNETHYAKVNEEG-QCQLAKVPDD--SKDFGLMANLFASDGLPGEVIHVRAKRRTGDLNFTEAIQDALKTEYGGRPISIGGVFLVRSGRTKLHVMT-DFSPDPCPGPD--HEWFKYYDSSAPLICLTVFHSADSEGDLRMEHAHCFSTHGMGGHYHYDTTAEEVEYEAWLNTAKLLYRIDQPG-------- -> ---VIECHTPSLDELKQVFETSLRENFQHVQVDIVKCPDTSEPPFEMTSTGFGKDMRIAEVGGPGNIYPVVRKENQFSFEKIAEVCQLPDGHVMGPGAGPWPIIGVNCEMVADANCAVN----QFETRVIKIDESTKGYELSRT--S--EPTFNLLANLAISKPRSSDVVHFKCSVRTGKKNLPETIRQGLATKFGNTPVSMAGVFILDNGKAKIHVMP-DFPSCAWGHEKEVNEWLRFFEMPGPLVNVSVIHSYDPGHKLRLEHTHCYSSQGDGGHYHYDVSPETVSYEGWFAPAQKIYRIDE---------- -> --QEKETHKPSLDEIRNVLEEALKKNFNEVSVEIVDNPDLKSEPFYLASSGISGNPLIIEYGNDDYLLPLVDKSKVYNLIPTIREIETYKEYVCGAGAGPFPLYDQNCEGIYNMKVFK-NGTIDNQSHIARTQGS--GTETLKLPNN--ETRAALLGNLFLSEGNDGKVLKVIAKNRTGEENFISAMRLGLSEKYSDEVVGLGGVFVMKKGIANIHVMD-RFSENPINTDEELNNWLTFHEMPAPLIALGNFVSHQTDFKLRYHHFHCFSKHNHGGHYHYDVTPDIVEYEGYFNIAERIILIDKS--------- -> -VKKLALNPPPLCELSQVIGERLSRNFGHVVANVVPCPDLRQPPFYLAGEGLCGSECIADVGGPPHLRPCPRLDKKYSLPTIMRMIETRQRFVLGAAAGPFHVVGQNSELMPNLARGH-DGEWLNETHYAKVNEEG-QCHLAKVPDD--SKDFGLMANLFASEGLPGDVIHIRAKGRTGGLNFTEAIQHALKTEYGAQPISIGGVFLVRSGKTKLHVMT-DFSRDPCPGPD--HEWFKFYDSSAPLICLTVFHSVDSESDLRMEHTHCFSTHGMGGHYHYDTTAEEVEYEAWLNTAKLLYRIDQPG-------- -> ----INTLKPSNNELRSVIETILWKNFKNVQVEVASSPDLTAAPFRMTSNGFGKNLVIAEVGGMGNLYPDLHKEKQYDIQEICEKCGAPKAFVFGPGACPSRVIGA-GELVADANLSEN----KVTSKVTTLVKNHLKYKTKII--N--STKFSLMGNLVVSEQGPSEVVHVKCSERTGEDSLPGCIRKGMAEHYGQSCVSLAGIFLLLRGKADVHIIP-DYPEKPFNSMDEVEKWFQIFNVSAPLVCASVLHSYDPGYKLRIQHTHCYSDHDDAGHFYNDTTPKIAEYEGWFTAAEKIYRIDE---------- -> --EKLELRTVGLDDIATVFQAALEANFTEVSVAVVDCPDLTLPPYRMAARGLSGSTKIADVGGVRYLTPTPQLDHIYSLRDVGKLTGSNDGFVIGAGAGPFQETGCNCELMADAFISTEADHSKIVSQTAKLNKDG-KCVVTSL--T--TPSLAILGNFFVSKGEPGKVIEIRAKRRTGADDLIACLRKSLARQFGGTPVGVGGVFLVQKGRVNIHVMP-DFSKTPLATQDEVDKWLQYFEFPAPMIFQSVFVSEDPGLDLRLEHSHGHSLHSHGGHYHYDTTPDEVEYVGFFNAAEALYRIDRPK-------- -> --TSKEIPPPPLEDIRVALEKALSENYKEAQVEIVDCPNLTEAPFGLAAPGLGGKTALADVGGVPYLVPGPALERVYNLDHTASQVDIPGALVIGAGAGSKHDVGVNSELIPNIRTRGGENKRRNLTHCSRIDPADSKSLLLRYEEDLNSADFTLLGNLFFSEGKSSKVLKVTTKTRTGTGSIVTCMRKGLAEAFS-VPVGMGGTFLQAAGTVKYHVMP-EFSACPLDSDDKVNAWLRYFNFEAPFVNMATFISKDPDLDLRVEHTHGYSTNQTGGHYHYDVTPETIEYVGYFTPAQKIYRIDAPTETHMIGRD -> -IKKVELAPPSLSALAQGIVSGLCSNFSISDCSVAIPPDLTAAPYHLAGSGLSGSPRIVDVGGPPNLSPTPNMTKKYDLTAIAGQVDMSPAFMLGAGAGPFYVLGQNSELMPNFAYGTGEDVVRNRTHYAKITPSD-TVCCAQIPQA--STGFAFMCNLFCSDGVPGPCLHVTARSRTGPLNFTESIQHGLQATFGDKLISLGGVFLIKKGKARLHVMP-DFPTQPFNSRADVERWLRYFDMDGPLVCLSVLHSGDDGLGLRMEHTHCFTVTTKGGHYHYDLDETEIEYEGWFNVAETLYRVDQPGI------- -> --RKYPLSPPTLSELAETLKVPLSTNYDHSTVRVITCPDLRNAPFHLATPGISGDEKIADVGGQANLFPRPRLDKIYSMPELAKAMEMGSEGLLGAGAGPFHVIGRNCELAPNFSWEGGFENVDNRTRVIQIRPDTGGVGVGVS--P--SVDCALMVNLYGSLGETGEVIRITARKRRGAKSFTECIQTALKEAYGSQTISLGGVFVVRSGKARYHVMP-DFPPEPFKNRKQLEEWLTYHDFGSPMVCLSVLHSADPKLGLRMEHTHCFSEENTGGHYHYNLKDEEVEYEGYFNAAKVLYRVDAA--------- -> --QKISLSPPTLSELAEKLQGSLSANYERSSVTVVPCPDLREPPFLLAHEGLSGDEKVADVGGQTHLYPRPMRDKTYALISISREMEIEHEMIIGAGAGSSDIVGQNCEMAINFGWRYQGSWRHNGGRYVKIEPGTDSVLLEKTDSA--RWWFGLMGNLFASDGGPGDVLKITARKRVGEGSFTECIRKALHAAYGSQIVSLGGVFVIKSGKARYHIMP-DFPPEPFRDRQRFNDWLTYHDFKGPMTCLTVLHSVDPKLGLRMEHTHAFSTENAGGHYHYDVEEEEIEYEGYFNTAKALYRIDKPEFS------ -> --EKAQLHIPSLQELCTVLQAGLESNFAEAQVNVVECPDLTQKPFCFPVPGLCGSPRITDVGGVPYLVPVVQKHKEYNMNTVSKELELPGAFILGAGAVSSRAVGMNAELIPLVLTETEKRAEVNSSYVASINPADGQCLQEKYSDKFSDCNFGLLANLYACEGKPGKVLEVRAKRRTGEHSLVTALRKSLEGHYPDKSLALGGTFIIQKGKAKIHIMPREFAVCPLNTNDEINSWLKHFEVTSPLICQSVLVSKDPGLDLRVEHTHCFSPHGEGGHYYIDTTPDT---------------------------- -> --ARYPLSPPGLEELAKVLEAPLAANYEHIAISVVECPDLRAAPFNLATTGLSGNEKISDVGGQSNLFPSPRLDTIWSMKELAQAMEMDPDSIIGAGAGPFHQVGRNCELAPNFSWGKDFGDVDNRTHIAKIDKDTGAPRVEKS--P--TLDCALMINLFGSEGKTGPVLKITARKRKGPSSFTQCIRKGLRTAYGKQTVSLGGAFIVKSGRTNYHIMP-DFPPAPFKDPKQLNDWLTYHDFDSPMVCLSVLHSADPEQGLRLEHTHCFSPNNSGGHYHHDIEGLEIEYEGYFNTAKMIYRMERPSVTLA---- -> ---HKPLCQPPLKYVAAVLEAGLKENFAEATVTVEECPDLRQAPWGLAGPGLGGETRVMDIGGVPFLMPLVQREKLYDMADYPKMAGLKEGLVIGAGAGPWPFLNRNAEMMPNLFVKA-DGTILQETHISRTHDEDGSFSTIKLPKE--ETRNSLLGNLFISSGEPGPVLKIHCKGRTGPKNLVTCMREILAEAWPSESLGLGGIFRIVSGKAKFHVMP-DFSPCPINTDAEVNQWLKFYEMDAPLNVLSVLVSRDPGLDLRVEHSHGWGENSQGGHYHYDTTPDDVEYIGYYNTAELCC-------------- -> --TTHPRDPPPLGELAAIIQRSLQANFASASVSVVECPDLRQPPFHLASSGLSGNPCIADVGGQPNLFPRPNFDAKFNLRSLAKDMQMTEGFLIGAGAAPFHETGYNAELAVNLYTPPDIDQVRNGSRIIQVNQDG-SSCCEVI--K--SLDCGLMVNLFGSSGDTGPVLKITARTRTGEQNFTNCIRLGLADHYGSRPISLGGVFILKAGKAKFHIMP-DFPKEPFRDREQLKEWLTYHDFEAPVICLTVMHSSDPRLGLRMEHTHCFEENRKGGHYHYDLQDGEVEYEAYLNVASTVYRIDRPE-------- -> ---CFILQPPPLEELRDVIQNGLRNAFETAFVEVTTCPDLSQSPFHLSAPGLCGDEKIADVGGPAYLQPVSDLTKKYTIPKILDLVGMEGQFAIGAAGGPFHVVGKNSELVPNLARDA-NGKWQNLSRYVHIDDDE-KMNLSMVPKD--TKDCGLMANLFISRGHQGESLHIRAKGRRGQLNFPETIQELLRVNYGGRPVSLGGVFLVKQGKAKLHVMT-DFSTSSCPGPD--HEWFRYYEADAPIVCLTAFHSVDYDWNLRMEHTHCFSESGVGGHYHYDTTPDDVEYEAWLNTAKAVYRIDQP--------- -> --TQHSLSPPALEELVNVLAPALDANFEMAKVSVEPCPDLRKAPYYLATEGISGEERVADIGGQPNLFPEPRLECKYSLVSIAKEMQMSSEQLLGAGAGPFHDIGMNSELAPNLSWEGSFDIVKNLTYYTKFVGSNHATVCEQS--P--SADCALMMNLYGSSGKPGSILKITARSRKGDKSFTECIRRALADKYGERPVSMGGMFLIKTGKAHFHVMP-DFPATPFKDPKQLNDWLTYHDFEAPIVCLTVFHSADPGKGLRMEHTHCFSDGGRGGHYHYDLMAGEVEYEAYFNVAKTLYRIDKPEVTLE---- -> --TSHTLSPPSLEELAQVLSPALKANFKTSSVTVERCPDLRKPPYHLATEGLSGQESVADIGGQPNLFPQPRLECKYSLLEIAKEMEMSGSQLLGAGAGPFHVIGMNSELSPNLSWEKSFDNVNNLTYYTKIEEDH-GKPIARCEKS-PCADCALMMNLYGSTGNSGPVLKITARTRTGSKSFTECIRRALFDKYGAHPISIGGVFVMKTGKAQFHVMP-DFPPAPWTQGSQVNDWLTWHEFIAPIVCLTVFHSADPGKGLRMEHTHCFTDSNQGGHYHHDLDVGEVEYEAYFNAAKMLYRIDKPEVTLE---- -> --ERFILSPPTLEELAEIISGPLSSNFEFANVEVVQCPDLRRAPFNLATEGLSGNERIADVGGQPNLFPSPRLDNIWNMRDLAKAMDMDPNSLIGAGAGPFHQVGRNCELVPNLSWDGNLATIDNQSYLAQIITDTGEVSVERS--P--SLDCALMVNLYGSSGLPGPVLKITARKRKGQKSFTECIRKAVTAAYGSRPVSLGGAFLVKTGKAFFHVMP-DFPPKPFESRKQVDNWLTYHDFEAPVVCLCVMHSADPGKDLRIEHTHAFSQANAGGHYHYEADGSDIEYEGYFNTASVIYRIARPES------- -> -IEKFPLSPPGLEELVAKLQAPLAANYEHSTVNVVSCPDLRQAPYHLATEGLSGDEKIADVGGQPNLFPRPKMDCVWSMTELAEAMDMNPAGLLGAGAGPHPVIGQNCELAPNIGWQGSFENVKNESRYAKIDKETSAVHVDKS--P--SLDCALMINLFGSSGSPGPVIKITARKRTGSRSFAECIRKGLRLAYGEQTVSLGGLFLVKKGKAKYHIMP-DFPTEPFNNRKDVDSWLTFHDFDARMLCLSVLHSADREGGLRIEHTHCYAAKNAGGHYHYDLDDTDIEYEAYFNTAKMIYRLDRP--------- -> -IETIQLNEINLDELSNRLLDGLRNKFEHCSVSVVDCPDLTRPPFNLAASGLCGRTAIADVGGVPYLLPLVKRDKIYSFKQIANIVDPGQQFILGASAGPFHKIGHNSELMPNVLLEKEGFKIRNDTHLAEIHDQNNRFRLLKS--D--HSEFGLLGDLFVSEGKPGKVLRIEVQNRKIKASFTTIIRKILQESYPNQLISLGGVFLIEQGEAILHIMP-DFSDVPLNTEQEVNDWLRFFPMKSPLRCLTTMHSVVDGYNLRSEHTHCFSDHNQGGHYHNDIDPKRIKYLAYLNTAKIIYRIDKPSITN----- -> -IQKFQLSPPSLEELAERLKSPLAANFHFSSVTVEVCPDLRQAPFHLATRGLSGDERVADIGGQPNLFPRPQLDKFWAMDELAVAMDMNNTSLIGAGAGPFHVIGQNSELAPNLNWEDGLQTINNQTRIIKIMKTTGDIGVEKS--S--SLDCGLMANLFGCSGESGPVLRVVARGRKGVRSFTECIRKALHSAYGDHAVSLGGAFVVKSGKAVYHIMP-DFPPKPFRDRGQVDAWLTWHEFQAPMVCLSVLHSADPGKGLRMEHTHCFSEGNAGGHYHYETDHSDVEYEGYFNTAKVIYRIDNPT-------- -> --KKATLSPPTLPSLASAIAAGLCSNFAQSSCSVATPPDLTLKPFHLAASGLAGATRVVDVGGPPHLQPTPDLSKEYDLLSISQQVGMNQSFMLGAGAGPFHVLGQNSELMPNFAYGTGSDQTRNRTHYAKITSSN-DVACCQL-PD--STGFGLMCNLFCSDGLPGPCLHITAKSRVGPLNFTETIQDALKSTFGDQLISLGGVFLIKQGKANLHVMP-DFLSRPFGSRKEVEEWLRYFDMEDPLICLSVLHSGNDGGDLRMEHTHCFTVTEKGGHYHYDLESTEIEYEGWFNVAELLYRVDQP--------- -> -VKKVELSPPSLASLADAIASGLSSNFAVSSCTVSTPPDLTHAPYHLAGPGLGGSPRIVEVGGPPNLSPSPNLTKRYDLAAIARQADMSPTFLLGAGAGPFDVLGQNAELMPNYAYGAGVEVVRNRTHYAKITPAD-TVCCAPIPHA--NTGFAFMCNLFCCDGVPVECLHVTARTRTGPLNFTATIQHALRAAFGQQLISLGGVFLIKKGTAKLHVMP-DFPAQPFTSRADLERWLRYFDMTGPLVCLSVLHSGHDGLGLRMEHTHCFTVTTKGGHYHYDLDETEIEYEGWFNVAECVYRVDQP--------- -> -VEKFPLSPPSLHDLAEQLGGPLRENYEDATVSVVDCPDLRQPPFHLCTEGLCGDEKISDVGGQPNLFPQPRLDSTWSMTDLARAMEMSAHGLIGAGAGPFHVVGQNCELAPNLSWKDKIENITNQSRLARIVPETNAVSLEKS--P--SPDCGLMVNLYGSLGQPGPILKITAKGRKGSTSFTECIRQGLAAAFGEETISLGGVFVVKSGKALYHIMP-EFPSEPFKDRQQVDDWLTYHDFDSPMVCLSVFHSADPNNALRIEHTHCFSATNAGGHYHHESTGAAIEYEAYFNTAKMIYRIDRP--------- -> ----INTLKPSNNELRSVIENALWKNYKNVQVTVDTSPDLSKPPFRMTANGFGKKLSIAEVGGMGNLLPILRKDKLYNTE-------KKSAFVFGPCASPASIVGATGEFIIDANFATS----KVAGKVTIQQKGH-TSPYKMLIFD--TPKFDLMANLAISEEGPGEVVHVKCSERKGEDNLPGCIRKELARHYGPSCVSLAGIFLLLQGKADVHIVP-DYPTDNFKSMDEVRKWFHMFNVKAPLVCATVFHSYDPGHNLRMEHTHCYSDHNDGGHYHTDTTPDTVAYEGWFTAAEKIYRVDQ---------- -> ----VALSPPSPSALAEAIASGLSSNFAYSSCTLAIPPDLTAAPYHLAGPGLTGSPRVVDVGGPPNLSPTPDLTRKYDLASIARQVDMSPSFMLGAGAGPFYVLGQNSELMPNFAYGTGASSVRNRTHYAKITASD-TVCCARIPDD--STGFAFMCNLFCSDGVPGECLHMTARSRTGPLNFTATIQRALRASFGDKLVSLGGVFLIKKGTAKLHVMP-DFPARPFASRADVDKWLRYFDMDGPLVCLSVLHSGHDGLALRMEHTHCFTVTTKGGHYHYDLDKTEIEYEGWFNVAEYLYRVDQPGTRH----- -> -VEKFPLSPPSLEELAERLKAPLDANYKHASVSVVNCPDLRKAPFHLATEGLSGDEKIVDVGGQPNLFPRPRLDSIWSLPEIGKKMEMSPESLIGAGAGPFHVIGQNSELAPNLSWQGGLDKVDNKSQVIQIKRATGEVSVGTS--P--SVDCGLMVNLYGSLGEPGPVLKITAKGRKGSRSFTECIRKGLNAAYGERTVSLGGAFVVKAGKATYHIMP-DFPAEPFKDRKEVEKWLTFHDFDSPIVGLSVLHSADPGNGLRIEHTHAFSPKNAGGHYHYEAEGEIIEYEGYFNTAKAIYRIDSPADTK----- -> --SIYPRDPPSLLDLAEVIQRSLQFNFTEASVGVEQCPDLREEPFGLAAPGISGNPCIADIGGQPNLFPTPNFNAQYSLLELATDMQISGGSLIGAGAAPFQDIGHNAELAPNISWKPSTLEIRNNTRIIEVNDEK-LPSCDGT----SSTNCALMANIYGSNGQPGLVLKVKARGRIGDQNFTNCIRHGLRDTYGSRPISLGGVFLLKKGKAKFHVMP-DFPSKPFRDREQLKEWLTYHVFKAPIVCLTVFHSADPELDLRMEHTHCFDADKKGGHYHYDIQEDEVEYEAYLHPASTIYRIDRPA-------- -> ---VHPLSPPPLDELARVLTSALEENYAYASATVVDCPDLSLSPFYLAGSGLCGCECVADIGGQPHLFPRPKLDKKYSLIECARDMKMNPEMLIGAGAGPFHVIGGNSELASNLSWSGGFNNVQNLTRFAKINGTA-EIMVRKS--P--STDCALMMNLFGSSGHSGHVLKIMAKSRRGSKSFTECIRRALNNTYGSTQISMGGVFLIRKGKALFHIMP-DFPNEPFKDRHDLNRWLTYHGFSAPIVCLTVFHSADPESGLRMEHTHCFSEKNEGGHYHHDLPPDEIEYEAYLNTAKTLYRIDQPET------- -> --RKVALSPPSLTSLADAIAAGLASNFAVSSCTVATPPDLTAAPYHLAGPGLTGSPRIVDVGGPPHLSPTPNLAKRYDLAAIAQQVDMSPSFMLGAGAGPFYVLGQNSELMPNFAYGTGESSVRNRTHYAKITAAD-TVCCAPVPQG--STGFAFMCNLFCSDGVPGACLHVKARSRTGPLNLTATIQRALTAAFGDTLVSLGGVFLIKHGTAKLHVMP-DFPPRPFGSRADVDRWLRYFDMTGPLVCLSVLHSGHDGLALRMEHTHCFTVTTKGGHYHYDLDETEIDYEGWFNVAEFLYRIDQPG-------- -> -VEKFPLSPPSLEELAEELKAPLAANYEHASVSVVQCPDLRNAPFHLAAEGLSGDKKIADVGGQPNLFPRPRLDSIWSLPEISRHMEMSSESLIGAGAGPFHVIGQNSELAPNLSWQGGLDHVNNQSQVIQIKRDTGAVSVGTS--P--SVDCGLMANLYGSLGEPGPVLKITAKGRKGPKSFTECIRKGLNAAYGDRTISLGGAFVVKAGKTIYHIMP-DFPSEPFKDRTEVEKWLTFHGFDSPIVGLSVLHSADPGNELRMEHTHAFSPKNAGGHYHYEAEDEIIEYEGYFNTARVIYRVDRPATTA----- -> -VEKFPLSPPSLEELAEQLKAPLAANYKHASVSVVRCPDLRNAPFHLATEGLSGDEKIADVGGQPNLFPRPRLDTIWSLPDIGRHMEMSPESLIGAGAGPFHVIGQNSELAPNLSWSGGIDRVDNQSRVIQIERGTGAVRVGTS--P--SVDCGLMVNLYGCLGEPGPVLKITAKGRKGPKSFTECIRKGLHAAYGDRTISLGGAFVVKAGKATYHIMP-DFPPEPFKDRKEVEKWLTFHDFDSPVVGLSVLHSADPGNGLRIEHTHAFSPKNAGGHYHFEAKGEVIEYEGYFNTAKTIYRVDNPNAS------ -> -IEKRSLLPPSLTELAHQLAPFLSANFTHAAVTVAPCPDLRKAPFYLACEGLSGNAKIADIGGQPNLFPRPRLDRIWAMDEVAKAMEMSPEGLIGAGAGPFHILGQNSELAPNLGWRDGLDNIINETRLIKILPGTGRVRVEKS--P--SLDCGLMANLYGSLGRTGPVIKITASGRKGDQSFTECIRMALRAAYGERQVSLGGVFLVKSGRAVYHVMP-DFPEEPFKDRSDVDNWLTWHTFDAPVVCLSVFHSADPHNNLRMEHTHCFSGQHVGGHYHYEAEGSAIEYEGYFHTAEAIYRIDAPAELG----- -> --TTYPLSPPSLDEIAGILRPALEANFQKATISVSQCPDLRKAPFHLAAEXLSGNESIADIGGQPNLFPEPRFECKYNLLDIAKEMKMSPEQLLGAGAGPFHVIGINSELSPNLSWEDSFENVNNLTYYTKFDGTKHAAICERS--P--SSDCALMMNLYGSSGLPGPVLKITARARKGDKSFTECIQQALYXAFRDRPISMGGMFLIKTGTAHFHVMP-DFPPKPFKNAKQLNDWLTYHDFKAPIVCLSVFHTADPGKGLRMEHTHCFSTSGSGGHYHYDLPAGEVEYEGYFNVAKTLHRIDRPVVTLE---- -> --TITPRNPPPLSELAPIIERALSQNFTHASASVTPCPDLRNAPFGLAARGLCGAPRIADVGGQPNLFPTPNFDAKFDLLALARDMQMDPAFVLGAGAAPFQDIGHNAELAPNLAWRGDSLHVTNGTRVVEVLQSNSTFGEAIKCRPSPSTNCALMVNLFGSSGDPGLVLKVTARTRTGVENFTNTIRAGLLQAYGSRPVSLGGVFLLKSGRAKFHVMP-DFPPAPFKDRKLLQEWLRYQTCEAPVVCLTVFHSADPENGLRMEHTHCFDLDEKGGHYHYDVEGEDVEYEAYLNVAQSVYRINRP--------- -> ---RVLLQPPSLNEVAAAVHNGLGSNFGTWSASVSTPPDLRQPPFHLAGRGLSGNPRVADIGGQSNLFPEVNLDKRYDLLKLSKQMEMTSGVLIGAGAGPFFDLGRNIELMPNIAFGASDGDVSNCTRYAKVLDDG-SALCEKI-GT--STGCGLMCNVFGCDGETGSLLHVKAKGRTGKLNFTEAIQKGLADTYGDRLISLGGVFVVCSGKLKMHVMP-DFPDEPLTSRQDVDQWLHWYDMDSPMVCLSVLHSGDDGLGLRKEHTHCFGASRRGGHYHFDLDETTVEYEGWFNVAEILYKID----------- -> --TKHLRDPPPLEELAAVIEKALLSNFKTASATVAECPDLKQPPFHLAASGLSGSPRIADIGGQQHLFPRPILNAKYSLLSLAQDMEMSPMFLLGAGAAPFQDIGQNAELAPNLSWRSSLLTFDNGTRVIKVQGDRDQTPVCDR---TSSTNCALMVNLFGSDGDTGPVLKINAKARKGEENFTDCIRYGLQKVYGSKPISLGGVFLLKSGKARFHIMP-DFPPEPYRDRKQLTEWLSYHIFQAPIVCLTVMHSSDPGLGLRMEHTHCFGVNPKGGHYHYDIQDGEVEYEAYFNVASVVYRVDRP--------- -> --QKRELSPPPLDELAGIIAAGLESNFEQSSVQVEPCTDLRKAPFYLAGEGLNGSTRVGDVGGPPHLAPP-DFSKKYDFMEISKLMEMPQEFLLGAGAGPFYVLGCNAELIPNISYEN--GEITNLTHYAKIAKDD-QVECQKI---ETSTGFAFMANLFGSEGLPGPALHIKASSRKGAPNFTETIQAAVQEKYGDKLVSLGGVFVIKRGRANLHVMG-DFPEKPLQ-RQDVDDWLRRFEFDAPLICLSVLHTGDDGMALRPEHTHCFSGGKNGGHYHFDVEDTDVEYEAWYNVAEAVFRIDSPGR------- -> --QKFTLSPPTLEELAEPLSAALRANYEHAAVSVIPCPDLRNPPLCLATEGICGDEKISDIGGQPNLFPRPQLTSRYSLPEIAQAMELHHHGLIGAGAGPFHIVGQNCELSPNLSWTAGLDSIDNRTHFAHIDRATGAVGVDKS--P--SLDCALMANLYGSRGEPGPVLKITARKRKQHRSFTECIRKGLRVAYGSRTVSLGGVFVIRSGSARYHVMP-DFPAEPFKDFEHHNDWLTYHDFAAPMVCYSVLHSADPKLGLRLEHTHGYCPRQAGGHYHYEVEGDEIEYEGYFNVAKTIYRVDRPAVTLD---- -> -VEEKPLFVPPLEDVVRTLQDGLPSYFHSVSVSCVECPDLTAEPFCLVAPGLCGSPKVVEMGGVSNFMPLYNPDKMYDLKHFNRLLGVDPVVVLGTGAGPFIDGHNCCELLANALISK--GEVQSLNRIAKVTDENRGYTIQFLPKN--ETKFVLMANLFASNGKPGKVLKINCKNRIKDEDFPAAVRKCLAEKFKDKPLGLGGVFLVEGSKVRQHIPPKEFSEVPITSPEQLNNWLRFFDMNPPLVFVGTILTQDMGLEMILQHFHSFSDHGEGGHYHHDTDPHSVEYLAYFSLAEKAVHVDRPPCISNL--- -> ----IETLKPSNSELLPIVESALKSNFKNVTVEVGPCPDLSAEPFSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDLK-ICKVCQSPFSFVFGPGAGPWKVVGRNCEMVADANLTTA-KVILSSGYVDPLNRRY--MLIFHYIIL--NASRSLLFS-------LCRLVHCKCSVRIGKDNFPETIRKALAKHYGERCVSLAGIFLLREGEAKLHIMP-DFPGCQFSSSEEVDKWLQFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSSHGDAGHYYYDTTPDTVAYEGWFTAAEKIYRIDE---------- -> --TITPRNPPPLSELAPVIERALSQTFTHASASVIQCPDLRNPPFGLAAPGLSGNPRIADVGGQPNLFPSPNFDAKFDLLALAREMQMNPRFVLGAGAAPFQDIGHNAELVPNLAWDGRTVSSPDLSDVDSLDSEDEAIKCR--PSP--STNCALMVNLFGSSGDPGPVLKITARTRTGVENFTNTIRAGLLKAYGSRPVSLGGVFLLKSGRAKFHVMP-DFPPAPFKDRKLLQEWLRYRTCAAPVVCLTVFHSADPENGLRMEHTHCFDLEEKGGHYHYDIEGEEVEYEAYLNVAESVYRIDRP--------- -> -IEKKTLHVPPLEEIATALNRGLRSNFEQVEASVVECPDLTQQPFTLACKGLNGTPKLIDFGGLAYAFPVAQKDKVYDVKDFVKTVKTDPAFVIGAAGGPHPYTILNSDGVYNLEIKN--GNVRNLSQTLIVDEDG-KAVQGSLPDS--ETRCAALGNFLICNGKPGKVVKVHVKKRIGSDDFVTSIRKVLVDTFKGQLIGLGGTFLLKEGKINVHITP-DFSKTPIVTVADLNAWKRFFDLTAPLVAVGTVTTNDGGIGLSDRHFHSFSHHGEAGHYQHDITPDTVEYLGYFVPAEEAYRIDRPEVA------ -> --KKVVLSPPPLSALASAISLELSSNFSESSCTVETPPDLTLPPYHLAGPGLTGSTRVVEVGDPSYLIKF-DFTRRYDLQPISRKTDMSPSLMIGAGAGPFYVLGQNTELMPNFAYGTSPEATRNRTHYAKITPAD-GVSCCQL-PD--SSKFGLMCNLFCSDGTPGPCLHIKAKSRTGRDNFTQTIQNAIGAAFNKQLVSIGGVFLIRSGKVNLHVMP-DFPASPFNNHDDVEKWLRYFEMEGPLVCLSVLHSGDDGLGLRMEHTHCFTDTTKGGHYHYDVDETEVEYEGWFNVAEHVYRVDPPP-------- -> ----------------------------------------------MTSNGFGRKLVIAEVGGPGNLFPKIRKEKEFDLQDVCKECHAPSSFVFGPGAGPWPVVGRNCEMVADANFASS----KVATKIASLVEGHTPYKMSI--ID--SPKFSLMANLAVSGEGPAEVVHCKCSVRVGKDNFPETIRKGLAKHYGKMCVSLGGIFLMREGEAKLHVMP-DFPGCPFKAREEVDKWLRFFTMKAPLVCASVFHSYDPGHNLRLEHTHCYSEHGDAGHYHYDTTPDTVVYEGWFTAAEKIYRIDE---------- -> --QKVPLSPPTLREIAVALQFPLAANYSHSTVDVVQCPDLRKAPFYLATAGLSGAEKISDVGGQPNLFPTPRLDCKWNLLDIARAMEMAPHGLLGAGAGPFHIVGHNCELVPNIAWNDGFENATNSTYLAQIRQGE--PSVEKS--P--SLDCALMINLYGSLGHSGPVIKITARGRVGDKSITELMRKALANAYGDRMVSLGGVFAVKKGTSKYHIMP-DFPPEPFKNAKQLNDWLTYHEFEAPVVCLSVLHSADPGKGLRMEHTHCASMRDVGGHYHGDINGEEVEYEGYFNVAKTLYRIEKPEVTLE---- -> --TRHLLSPPSLDELAQALHPALTANYEDASISVVDSPDLREAPYRLAARGLSGNECVADIGGQPHLFPRPRLEKKYSMLECAQCMEMSKDLLIGAGAGPFHVLGKNSELAPNLSWTDGFSKLENKTHFAMTGEHNTDVVCEPS--P--STDCALMMNLYGSSGNAGPVLKVTARARKGEKSFTECIRQALHQVYGERQITLGGVFVIKRGKALFHVMP-DFPPEPWKEREQLNSWLTFHEFGSPMVCLTIFHSADPKLGLRMEHTHAFSSKSEGGHYHFDLPVGEIEYEAYFNTAKVLYRLDQPEVR------ -> --ARYELSPPSLEEVAKVLASALPRNYAESSVEVVDCPDLRKPPFYLATEGLGGRRTIADVGGQPNLFPRPRRDKNYSLIETAKLMKLDPDSLIGAGAAPNHVHGINSELAPNLSWQGFDHNVNNLSRSVRIVPGDVADSVGSIFSG--STECSLMVNVYGSLGLPGPVIKVTARGRRGTGSISEFMRTALRDVYGDRQVSLGGVFVLKSGRANFHVMP-DFPSGPFKDRKAVDSWLTFHHFAAPIVCLSTFHSADLHNGLRMEHTHCFSDKPVGGHYHYDLVGEEVEYEGYFNVADTLVRIDQPK-------- -> -VEEKPLFVPPVEDVVQALQDGLASYFGSVSVESVECPDLTAEPFCLVTQGLCGSPRVVEVGGVSNFMPLYNPDKIYDLKDFNQLLAVDPVVALGTGAGPFLDNHRCCELLANARISN--GEVQSLNRIAKVTNENRGYIVQFLPKN--ETKFVLMANLFVSNGKPGKVLKIHCKNRIRDEDFPAAVRKCLAEKFKGKELGLGGVFLVEGSKVCQHIPPEQFSKVPITSPEQLNNWLKFFNMNPPLVFVGTILTHDMGLEMILQHFHSFSSHGEGGHYHFDTDPHTVDYLAYFSLAEKAVHVDRPQCTSTLK-- -> --SKHTLKPPPLEDIATKLQSALANNYRHSSVTATECPDLRHAPFHLATQGLSGNECIADVGGQANLFPTPRLECKYSLLDVAKAMEMDPESLVGAGAGPFHVVGQNCELAPNLSWKGSFDNVENRTYVAKIAKDSGEAMVSRC--S--STDCALMVNLFGSSGMPGPVLKITARGRKGKGSLPECIRTALHAAYGSQPVSLGGVFLVKSGKARYHIMP-DFPSAPFENRDDVEKWLTYHTFAAPTICLTVMHSADPGLGLRMEHTHCFASQNAGGHYHNDVESD----------------------------- -> -ITKLALSPPPLSDLATAIAAGLRTNFTTSTVSVSTPPDLRNAPFFLAGPGLSGNARVADIGGVQNLRPTPNLDAKYDLLGIARLMGMSDELLVGAGAGPFHHLGYNSELMPNIAYGASDGVINNCTHYAKITQDG-GVRCEKI-G--ESVGFALMANLFGCDGETGPILHVTARGRKARQSFTESIRAGIRAVYGDKLVSLGGVFVIHKGKTKLHVMP-DFSDKPLRSPDDLDGWLRYFDTDPPLVCLSVFHSGDDGDGLRMEHTHCFAGDCRGGHYHGDVDETDVEYEAWFNVGEVLYRIGQPD-------- -> ---ATPRKPPPLAGLAAIIQDALRQNFAHASAEVIECPDLREAPFELAAQGLSGNPVIADIGGQANLFPTPNLDAKFSLLALARDMRMSPELLIGAGAAPWQDIGHNAELAPNISWEGASISVTNKTRIVEVNPSANSSPEHSICRPSPSTNCALMANLFGSSGLPGPVLRITARSRTGAHNFTNAIRHGIHAAYGSHPVSLGGVFLLKSGSAKFHVMP-DFPSRPFRDRKQLEDWLKYQTCAAPVVCLSVFHSADPGLGLRMEHTHCYDLREKGGHYHYDLQDGDVEYEGYYNVAEVIYRIHRP--------- -> ----LRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISASKLQTGQLIGAGAGPFFTAGKNCEMAAIVKVAEN-DVRSNNTLHGVYNKSED--KPGVLKAT--DNNFALLGHFLATEGNPGKVLAVDVSVRAKDGSIYTFLREALTAKFGSAPVALGGAFVLDNSKGRFHVMP-DFPKEPVDSPAKISSWLKFYEMSPPVMGVGTIVSHDPKMDLKLEHFHCYSEGAEAGHFYYDTQPETAHYRVYLAPAKSILRIDRA--------- -> --KKLFLSPPPLAELATSISAGLSTNFSSSSCTIETPPDLTLAPFHLAGPGLTGSPRVVEVGDRSYLVKR-DLTRKYDLRAVARQIDMNPSLMIGAGAGPFFVLGQNSELMPNFAYGTNAQSVRNRTHYAKLKPDG-SVQCSALS-P--TSSFGLMGNLFCSDGEVGPCLHIRAKSRTGALNFTETIQEALKTSFGDKLISIGGVFLITSGRVNVHVMP-DFPAQPFKDRAAMTTWLRYFDMGKPLVCLSVLHSGDDGGGLRVEHTHCFTETDKGGHYHYDVDDTTIEYHAWFNVAEYVYRIDYPAEHQR---- -> ---HRALSPPSLSSLAASISSGLSTNFAHWSCDVETPPDLTLPPYHLAAPGLSGSTRVADVGGPPYLESKLDLTRKYDLAAIAQDVNLPASFLLGAGAGPFFHLGHNSELMPNYAYGTSSPAIRNRTHYAKITPSNDPV-CCPL-PS--STGFGLMCNLYCSQGLPGPALHIKAKARTGPLNFTQSIQDGLKATFGENLISLGGVFILKSAKAKMHVMP-DFPKNPFQSRKELVEWLRFFDMTGPLICLSVLHSGDDGGDLRHEHTHCFTVTSKGGHYHFDLDETQVEYEGWFNVAEDLYRVDQPG-------- -> ----IETLKPSNRELRPIVETALKTNFKNVSVEVVSCPDLSIEPFSMTSTGFGRKLVIAEVGGIGNLFPIIHKEKEFDLQEICDSCQAASSFVFGPGAGPWKLVGKNCEMIADANFSIS----KVATKIVSISSSDPSYTLSIL--N--SPKFSLMANLALSEPGTG---ECTANVRFELIIFLKLYEEGLLNITEKSCVSLAGIFLLREGEAKVHVMP-GFPGCSFNTKEEINKWLRFFTMKAPLVCASVVHSYDAGYKLRMEHTHCYSSHGDGGHYHYDTTPDTVVYEGWFTAAEKIFRIDE---------- -> -----------------------------------------------TSNDFDRNLTIAEVGGPGNLFPTIHKEKEFDLKKICEECHAPSAFVFGPGAGPWQVVGKNCEMVADANFAI----PKVATKVAFINDGQ-STTYKQSTID--SSKFSLMANLAVSGEGPGEVVHCKCSVRVGKENFPEAIRKGLAEHYGSRCVSLGGIFLLREGEAKLHVMP-DFPGCPFKSTEEIDKWLRFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSEHGDAGHYHYDTTPETVVYEGWFAAAEKIYRIDE---------- -> --DEFQLEKLELETIQNALNKNLPKFFEKVSVSVSDCPDLTQQPYNLATEGIGGKGSLIDIGGPPYLIPLVNREKVYDLAKIIEHVGKEDGYASGAGAGPWPSQGSNCEMVINLKLDKDGGVVSNKSKVALTSSGAEDLTVKELGNE--ESRCALLANLLVSGG-KGKIIEIKCTKRIDKSNFTAAIRQALKEEFGEKPVGLGGLFTVTLSDTKIHVMR-DFSNTPLESDDDVNNWLKFFHIKPPMLFQSVLVSSDPGLDLRIEHAHGWNLRSEAGHYHYDDMPDTVEYHGIYAVAQKIIRIDRPQETHQLGRD -> --SKKILYQPPVTELISVLTDGLTANFEKVIVKLGRCP--RDPERQPNQYDLCGDPTILEIGGPAYLLPLAQKDKFYNIETLLRRIDYHGSFVIGAGAGLWPHTGSNCELIIHHHINTQIGSVVNNSRYAFVDKCTGECVVAQHHNEQHQATCPILANLYVCKGEPGMVIKVYAKKRTGKLDFIASMQKALGNYYKDELVGLGGMFTMRNGKIKQHVMP-DYSNTPLTTEAQLNDWLHFYEMKTPLTAVGTFVSAETELDLRVQHFHSFAHNKMAGHYHIDTTPDTIEYEGYFNIASVLYRVDQPTNKLQFGKD -> -VEKFPLSPPSLEELAKNLGAPLAANFKESSVRVVQCPDLREAPFRLATEGLSGDEKIADVGGQPNLFPRPRLDNIWSMAELSKSMEMSPESLLGAGAGPFNIIGQNSELAPNLSWRGGLENIDNRSQVIQIRRGTGAVSVGT--SP--SVDCGLMVNLYGSLGERGPVLKITAKGRTGPKSFTECIRKGLRAAYGERTISLGGAFLVKSGRATYHIMP-DFPPEPFKDRKQVDDWLTFHDFDSPIVGLTVFHSADPGNGLRIEHTHAFSPKNAGGHYHYEADGSEIEYEGFFQTAKVIYRVDRPSTA------ -> --ETFPLSPPSLEEIAAHLQAPLAANYTHASVGVVRCPDLRAAPFHLATEGLSGDEKIADVGGQPNLFPRPRLDTIWSLPEVARAIGMSPEGLIGAGAGPFHVLGQNSELAPNLGWSGGENEIDNQSRVILIERGGKKNAVSVRAAP--STDCGLMANLFASRGEPGPVLRIAARGRKGPKSFTECIRQGLRAAYGERTVSLGGAFVVRAGRATYHVMP-DFPPEPFRDRRAVEDWLTFHDFDAPVVGLSVLHSADPGMALRMEHTHAFSAEDAGGHYHFEAEGEVIEYEGYFNTAKAIYRVDRPAG------- -> -VKKVALSPPPLHALAEAITSTLSSNFSSSSCTVETPPDLTLPPYHLAGPGLTGSPRVVEVGDPSYLVRS-DFSRRYELRAIASQADMSPTLMIGAGAGPFFVLGQNAELMPNFAYGTASTMTRNRTHYAKITSPSDAVSCCPLPS---SSNLGLMCNLFCCDGEPGPCLHVKARSRTGPLNLTQAIQQGLKSAFGDRLISLGGVFLIRKGKARLHVMP-DFPAQPFRDHDDVVKWLRFFDMAGPLVCLSVVHSGDDGLNLRMEHTHCFTETTKGGHYHYDVDDTEVEYEGWFNVAESVYRVDYP--------- -> -VKKVTLSPPPLHALAEAITPTLSSNFSSSSCTVETPPDLTLPPYHLAGPGLTGSPRVVEVGDPSYLVRS-DLGRRYELRAISRQTDMSPTLLIGAGAGPFFVLGQNTELMPNFAYGTDTMTTRNRTHYAKITPSD-AVACCAL-PD--SSNFGLMCNLFCCDGAAGPCLHVKARSRKGPLNFTQAIQQGLKSAFGGDLISLGGVFLIRSGKAKLHVMP-DFPAQPFRDHDDVVKWLRFFDMDGPLVCLSVVHSGDDGLNLRMEHTHCFTETAQGGHYHYDIDETEIEYEGWFNVAESVYRVDYP--------- -> ---KLSLKVPPLEELSSILDPALRKNFGQISIDIVDCPNLREAPFSMTGAGIGNGLRIAEVGGIPNLYPRGG-KKIFNLKKVCETCEMPHAFVFGPGAGPFEAVGHSSELVANANFIE--HEYKVANKVSWVVPSGKGYTMSTI--D--SSDFEITANLAISDGCPGKVLRIRAAKRNGEMNYPEAIQKALGAHYGDTLVSLAGLFVLQKGKVRMHVLP-DYPESPRKADEKKDDWLQYFEMDAPIVFASVVHSNDVGGKLRVEHTHGYSEHGDSGHYHIDTTPNTVEYEGYFSPANIVYRIDM---------- -> --TKYELSPPPLDELAAVLQTGLQQHFESVSVHVTRSPELREAPFHLAAAGISGRERIGDVGGPQNLRPLPRLDHKYHLREIMDLMEMQDGLVIGAGAGPFHHVGGNTELMPNLSYTD--GVANNQTRFARIVPATLAHRCRPLPAP-KSADSALLTNLYASDGAPGDVLKMVAHGRKPDPDFTAAIQDVLRSTYS-QPVSLGGVFVLRRGRALLHVMS-DFKTEPRLPG-NQDNWLTFFDVAAPLTCLSVVHARDPGLRLHLEHTHCFSERGEGGHFHHDSTPADAEYEAYFNTAKVIYRIDGPG-------- -> --TRLELSPPSLQEIAQVLAAALPRNYVASSATVVDCPDLRKPPFHLAAEGLCGGEVAADVGGHTHLVPRPRLDKNYSLPALAKLMQLSPDSLIGAGAGPNHVHGYNSELSPNLSWKDFEHVTRNLTHSTRVVGDRAGVACGLS--N--SADCSLMVNLFGSEGRPGPVIKVTARGRCGNASFTEFLQAALREAYGDRQVSLGGIFLLKAGRAHFHVMP-HFPTPPFEDQKTLDTWLTFHDFAGPIVCLSVLHSADPQKGIRLEHTHCFSNKPEGGHYHYDLGDEQVEYEGYFNVAHAFVRIDKPK-------- -> ---KLDLLSPELEELAPILNVEMENYFQEIDVDIVDCPDLTKPPFNMTSRGFGPDLRIAEVGGVGNLFPKIRRDKLYNLKSICDLCELPNGSVFGPGAGPRTSVGVNCEMVADANFGE----GTVNSKIGKIDGQS--FVQETTC----DPCFGLLANLGVSSGETDLVLKITARNRLTDYSFPHAIQQALFNHYRAKIVSMAGIFIQKTGDAKVHIMP-DFPERDFSCWEEEKSWLRYFKVRSPLICCSVLHSVNPGIDLRLEHTHCYSDHGDVGHYYTDIDPETAQFEGYFSPAKFLYRIDQIDS------- -> --TTHPLSPPTLGEICSTLRPALKANYSDSSIEIVTCPDLTAPPFHLASQGLSGKESIADIGGQAHLFPRPLKEKKYSLVDCAKSMGMSQQLLIGAGAAPWHVIGQNAELAPNVSWEGEESRVRNQTFVTRVESHGGQVRCERL--P--SMEFALMMNLFGCEGVTGDVLRVTAKGRRGQGSFTECLRQALHAEYGERQVSLGGVFVMKKGKAVFHVMP-DFPPEPFPSHDAVNEWLTFRQFSAPIVCLSVLHSADPKLGLRMEHTHCFSDKDEGGHYHHDILPDE---------------------------- -> -----ARNPPPLSELGSIIARALQQNFAHASASVTQCPDLRKPPYGLAASGLSGNPRIADVGGQANLFPSPNFNAKYSLLSLARDMEMSAEFVLGAGAAPFQDIGHNAELAPNVAWQADCVDIVNETRIVEVVAGEDSVSCWRA--P--SANCALMVNLFGSSGLPGPVLKITARGRTGPANFTSSIRAGLLAAYGSHPISMGGVFLLKAGKARFHVMP-DFPAPPFKDRRVLQEWLKYHTSEAPVVCLTVFHSADPGLQLRMEHTHCFDLCRKGGHYHYDLETDEVEYEAYLNVAEVVYRIDRP--------- -> --NRHELSPPSLTEIAQVLASALSENYASSWATVVECPDLRQAPFNLACEGLSGAEVIADIGGQANLFPQPRLEKNYSLIKCAEAMGMIPTSLIGAGAGPNHVHGVPSELAPNLCWKNGFENVNNMTRSARLIPQNEGSESAVACPYSGSTDYSLMMNLYGSHGLPGQVVKVTARGRRGDASFSEFLRSALRKAYGDHQISLGGTFIMKRGKAKFHVMP-PFPPQPFKSQEALDGWLSYQTFSGPMVCLSVFHSADPKRGVRLEHTHCFNGDSQGGHYHYDISSDQVEYEGYFNTAKTFVQIDKP--------- -> -ITKRPLHQPPLDELMSVLREGLAANFEEVSVELGTCPDCERKP---SRYDLCGNPIILGIGGPAYLLPLPQKDKLYNIEGILRRIDYRNAFVIGAGAGLWPRIGGNCEAVVHHHIDTRVGSVINNSRYAYVDKSTGECVVQQIGDNEQHQAIMLLADLYVSEGEPGTVVKVCAKTRTGKSDFITSMQKALANHYKDKLVGLGGMFTMRNGKIRQHVMQ-DYSDIPLTTEAKLNNWLRFYEMETPLTAVGIFVSAETDLDLRVQHFHSYAHNKEAGHYHIDTTPDTIEYEGYFNVAGTFYRVDQPPNRLQFGKD -> ---SAKLHVPSLDELVPLLNDALSKNFAEVEVKVLDCPDLTKAPWHLAGKGLCGSCRLLDIGGEFNLFYAKNHTALYNFDECARLAGVPKAFMIGPGAGSRPIIGKNCELMANVNIGEK----NFASYVAKITDDE---RPQQVNYP--ENQLGILCNLFACDGEPGKVIYFRAKKRTGERNVVSCMREGLRPVYTGQTVGLGGAFRIVKGKAHAHIMP-DFLERDMP-VEEVKSWLRFFEYEAPLTCLSVFLTEDIDLNLRLEHTHFFSDHNQGGHYHYDTTPDEVEYEGFFAPCEHVFRIGQP--------- -> --------------------------FVEVSVTVVECPDLTNKPFMLASQGLCGKPRVMDIGGTAYLLPTPQMDKVYDLSQVPSWSELGSSLSIGAGAGPSAVVGKLVELIPNIFIDE-LGKVHNHTHISKVDDKTGQHVVEKLG---NCCDSNHLTNLFVSEGRPGKVLKVIAKHKKSEGNFICGMQSSLKQRYGTQPVGLGGVFVLTKGKARIHVMP-GYAEYPLTSISMINEWLKFYEMSSPLTAVGYLMSHDPGLNLRMEHFHCFSDHGDGGHFHHDVTPELAEYEGYFNVPEYMFRVDL---------- -> ---EFVLHKPSYHEVSAALESHLKDCFESVKCSITDCPDLSDTPFCLTLKGLCGKGTICDVGSFDYLLPVPKTDRHYDLLDVFKSAGITVGAVIGAGAGPFFLTGSNSEMVINISSEN-GKVSKNSSLLGSYDKENNKPLITKA--D--NTKFALLGQMYMCEGKSGPVIELCVSGRIRDGKLDAMIREALHKKYGSSSVGLGGVIIQEKGKSLYHVLP-EFSQEPIDSNEKLRNWIKMFEMESPVISVGIVVSHDPHHGLRLEHFHCFNDHTNCGHCHFDTHGPSVSYRAYFALAEHLVRIDQPK-------- -> -ITKVQLDPPTLTALLPAIRAGFSSNFKNSIIEITQSPDLRQPPYYLATPGLSGHPRIADVGGQLFLAPGPDFSKKYDLLSVARQMEMSTEQLIGAAAGPFYSLQINTELAPNIHWKLATDVLYNETHYTKIIASEPGYRCSKIDHE--TTGFGLMGNLYGSDGLPGDLLHIVAKSRSGPLNFAATIQDALAKYFGDKLISLGGVFVVTHGKIKVHVMP-DFPERKFERRADVGPWLRYFNLEAPLVCLSVLHSGNDGLSLRMEHTHCFSNAVSGGHYHYDLDDTEVEYEGWFNIATVLYRIDQPP-------- -> --SNHSVHEVQKEELVEVLREGLKDCFQSVKVNVVPCPDLTALPFGLLRPGLAGQSVACDVGSMAYLLPVADTSKRYSFDQVVDLSKVSGGHLFGAGGGPFFTHGKSCEMAASLEFAN-GKICSNSTLHGVYDEQTGAPQVIK--AT--DNNFGLVGQLLSTEGLPGSVIEVDVTGRLKEGSVYVFLREALTAAYGDKPVVLGGVFVLTDSKARFHVQP-NFPPYPVDTPARMAEFIKAFEMDPPVLGMGTLVSHDPGIDLKLEHFHCYNAKNLAGHFYWDTEPEKAHYRLYLTVAKSLLRIDPKKK------- -> ---NHNAYDVQEEELAEVLREGLKDCFRSVKVNVVPCPDLTASPFGLLRPGLAGKSVVCDVGSMTYLLPVANTSKRYSFGQVIESSGVCGGQLLGAGGGPFFTHGKSCEMAASLQFAN-GKIASNSTLHGVYDEQTGTP--QVINAT--DNNFGLVGQLLSSEGLPGSVVEVDVAGRLKEGSVYVFLREVLTAAYGDKPVALGGVFVLTDSKARFHVLQPNFPPYPVDTPARRAEFIKIFEMDPPVLGMGTLVSHDPGIDLKLEHFHCYNAKTLAGHFYWDTDPEKAHYRLYLTVAKSLLRIDPKEK------- -> ----------------------------------------------MTSNGFGRKLVIAEVGGPGNLFPTLHKEKEFDLHQICKDCNAPSSFVFGPGAGPWQVVGKNCEMVADANFASS----KIATKVASIEEGQKPYKVDVI--N--SPKFSLMANLAVSGEGPAEVVHVKCSVRSGQDNFPETIRKGLAKHYGEKCVSLCGIFLLREGEAKLHVMP-DFPGCPFKAEEGVNKWLRFFTMKAPLVCASVFHSYDPGHKFRMEHTHCYSDHGDGGHYHYDTTPDTVVYEGCME-------------------- -> ---RHKLDPPPLDELANALSDGLARFFADVLVEVVDCPDLTAAPFGCAFSALGGDPCIIDVGGVDNLFPCARRGKYFDLSAIEQQIGAGRSCFIGAGAGPFQEVQHNCEWICNVRLPE-----ANESRCAVMEGTDSGYTIERP--K--TTCFGILGNLYACKGEPCKVLHIKAGRRTGKKDLPQCLASILASSFPSRPVSLGGVMAMHAGKARLHIMS-DFTDDPIRSNDAIENWLNYFEVPAPMTFMFVSTSIDPGMDLRTVHTHGWHEGKYGGHYHNDTTPDEVSYEVYVNVAECIYRIDRVSQTPDFNR- -> ----------------------------------------------------------MEVGGPPYLLPLVDRTKLYDIKTLSQRA-LGNKFAIGAGAGPFPLRGTNCEGIYNLKISA-DGKVTNKSYSAKVHGPEENCVLEQIPDT--ETKFGLLLNLFLSEGKSGKVLKVHCKKRTGPLNFIESIRYALLDFYKEKCVGLGGMFMIKSGKAHQHVMR-DFSKTPIYSEEELNQWLKFYEMPAQLNGVGTLITHENDLDLRLQHFHSFSSSNWGGHYHYDTTPDTVEYEGYFNVGEKVIRVDKPVNTHKFGRD -> ---VIENYVPSLNELKEVFKSALTSNFETVEVDIVDCPDLSKSPFNQTSSGFGCNLRIAEVGGPGNLYPGFHIDHQFDISTIGKVCEHPEASVFGPGAGPWPVVGQNCEMVADVNLKT----GKVGTRIAECDVKTKDLRSKSI--D--------VQNSYISKYQPG-------KERK-------TLQTVLEKDYRSEVVSLAGQFIIHTGQAKLHVMP-HFPGCPFKNNEEVDKWLNYFIMNAPLVCTTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEVA-------- -> --TRHALSPPLLHEVAAVLATALPRNYRCSSATVVECPDLRTAPFGLAAAGLSGRPTVADVGGQGNLFPTPRRDKNYGLVDVAARMQLDEQALLGAGAGPNRVHGINSELAASLSWQGEAKNITDCSRSIRIAADNGHDHVQCVLS--GSTECALMANLYGSLGLPGPVLRVTARGRHGNASFPEFLRATLHDAYGDRQVSLGGVFLFKTGRARFHVMP-DFPPAPFADRQAVERWLTFHDFAAPIVCLSVFHSADPQLGLRIEHTHGFADRPAGGHYHYDHLAREVEYEAYFNVADALVQIDPARA------- -> --KTYDLDQLPLDELSSTLQDHLSKFYGHVEVSVVDCPDLSKEPFNLAGSGLGGKTALADIGGVPYLMPVPYPAPIYSFVNLGKRMGFQDAHLMGAACVPFQITGSIAEFMPNISYSEGKTLVNHGSYYSEMVDD-KKYIMRPLA----SDCTNTLANVFISENKPSKVIKIVASKRVDKESLTVAIRDILRIAYPEKAISMGGMFLVRKGKIYIHVMPNDFSKTPCDTEEKANEWLNFFEASAPIVGLVTLHSKDPGFNLRDEHTHCIG-KGEGGHYHHDTTPDTIEYEAYLNIAQQIVRVDQPVVGNE---- -> ---RFKLNTPPLRCIIEAILPELLDNFENASVEVVQCPDLTQPPFNLTSEGLCGDENVFDIGDVTNLLPSLKREKLYNVKDLKQITGSDPLFIIGACAGPYPFFGADSECVENVKMTG--DRVENGTHVHMTKSDDPECFHKSLPDD--EMRFSMMANFFTSNGFKGEVLKIVCEVRKGPLSYSTCIKEALVKHFGNEIIALGGVILIENGKVKVHVIKPSLTKIPIKSEKELGNLLHFIELSPPLVGVGCIVSHDPGLNLRLQHFHLYTDHNQGGHYYNDTEPETIKYTGYFGVSKQFTKID----------- -> ---IYPMMPPNILEIADVLQNGMQPLFHDVRVDIASCPDLTTAPYNLAGVGLGGNTSLVEFLRHDVHTPWKH--RTRDILKVFTGS-IRDSFIIGSTFATKPTMPYYGHLIMNAMYTA-PMGIRNESRLIFAELRNGQTRIEKLTDP--NQMIYCKGNFFISEGREGPVIRVRAKGRKKSTDIITSMQTVLYEHYGWKTVALGGVLKMTNGRVACNLMW-DEYQEPILSFPDFVRAQQCICLESDMVAVGTIFNRQPLLEQRRSEFHCFNNYGAGGQFISDTTPDTTEYEGYFNVAENI--------------- -> ---VKELHMPPMEEVVETLQTALKANYKEVEVAIVDCPDLSSPPWDLAAKGICGDNCILDVGGVKNMYPINHPLKQWDIEELAKRVGMPGGFFIGAGAASPKIIGDNGELAPNTNIGTK----QIKTRSAEVAEDG--SCVQRM-YP--SNDVSAMANLFGSKGCAGKVIKVHVKVRTGKKSLITCMRQGLIKKYGDNPVALGGVFQLLQGKLKAHVMP-CFPQQDLVSQEIVDDWLNWYEVPAPATCLSVQVTQNMGLELRVEHTHFFTSNNHAGHYHYDTTPDECEYLGYFGIAEKLYRVDK---------- -> ---NYDVHEVRKEAVVEVFRNRLKEYFKSTKVNVVPCPDLTSPPFGLLRPGLAGQSVVCDVGSMSYLLPVADTSKKYSFDQVVESSGVHSGHLLGAGGGPFFTHGKTCEMAASLQYEN-DKIISNSTLHGVYGEQTGTPQVIK--AT--DNNFGLVGQLLSTEGLPGSVVEVDVADRLKEGSVHVFLREALTDAYGDKPVALGGVFVLTDSRARFHVLQPNFPPHPVDTPARMAEFIKVFEMDPPVLGMGTLISHDPGIDLKLEHFHCYNAKNLAGHFYWDTEPEKAHYRLYLTVAKGLLRIDPKKKTQSV--- -> ---RIKLNTPPLRCIVEAILPKLLENFENVSAEVVQCPDLTKSPFNLTSEGLCGDENVFDISDVTNLIPSIKREKLYNVKDLKQITGSDPLVIIGACAGPYPFFGADSECVENVKITG--DHVENGTHAFMTKSVDAECFHKSLPDN--EMRFSMMANFFTSNGIKGEVLKIVCEIRKGPLNFSTCIREALVKHFGDEIIALGGVILIENGKVKVHVVKPSLLKIPIKSEKELSNWVHFFELSPPSVGVGCIVSHDPGLNLRLQHFHMYTDRGQGGHYHNDTEPETIKYTGYFGVSKQFTKID----------- -> --EEFVLPSVDIEDICKALNENLKAYFQNVDVNVVDCPNLAEPPYNLATNGIGGYCVIADIGGVPYLIPLVQRDKVYDLRTLIPECVGADKYISGAGAGPFKSQGSNCELIVNMYLSP-DDKVVNRSKVALTSSQNTDLTVKTLSDT--ETDSSLLVNVLVSSG-AGKVLDIKVSHKLDPTNFTTILRDCLNKKFTSTPVGLGGLFTVDRAPTKIHVMR-DFSTKPLLTDNDVEEWLKFFRVEPPFMSQSILVSTDPGLDLRVEHSHGWTTPAQAGHYHYDTAPQDVQYHGIYAVASKIVRIDRPKETHNIGRD -> --TTHPRDPPPLGELAAIIQRSLLANFASASVSVVECPDLRQPPFYLASSGLSGNPCIADVGGQANLFPRPNFDAKFNLRSLAKDMQMTEGFLIGAGAAPFHDTGYNAELAVNLYTPPGP---HVGTGDPDVDQVRNGSRIIQVNQ----------------DGDTGPVLKITARARTGDKNFTNCIRLGLADHYGSRPISLGGVFLLKAGKAKFHIMP-DFPQEPFQDREQLKNWLTYHDFEAPVICLSVMHSSDPGLGLRMEHTHCFEANRKGGHYHYDLQEGEVEYEAYLNVASTVYRIDRP--------- -> ---SAKLHVPSLDELVPLLKDALSKNFAEVEVKIADCPDLTQEPWKLAGKGLGGNGRLLDIGGEFNLFYEKNHGSLFNFDECAKLAGVPKAFMIGPGAGSRAIIGKNCELMANVNVGEK----KFDSYVAQLTSDER-PLQ--VNYP--ENQLGILCNLFASEGEPGKVIYFRAKKRTGEKNVVSCMREGLRPVYTGQTVGLGGTFRITKGKAHAHIMP-DFLERDMP-VEEVKSWLRFFEYDAPLTCLSVFLTEDIDLNLRLEHTHFFSDHGQGGHYHYDTTPDEVEYEGFF--------------------- -> ---KRTLYTPSLTEVASVLEKALKKNFKEASVTVCQCPDLTKMPFKLAGAGLNGNTAVADVGGVINMEFLSNNKYHYDVKELSKEV--GLPFWIGAAATKPALAKDNSELMPNLNVAS----GVNNSKEAYVGTDGN-GHLVDY--P--HSEFSSLGNFFVSEGKPGQVLKIIARNRTGKLNMVTCMRQGLAEHYGDKQVGLGGVLLINKGKIRSHIMP-SFPPCDVYGK-QGIEWLKFYEVTAPFTCLSVLVTHDKYKDLRLEHTHFFSHGKDGGHYHYDTTPEQVEYEGYYNIATDLYRVGRPA-------- -> ---HIKLNTPPLSCIVKAILPELLKNYENASAEVVQCPDLTQPPFNLVSEGLSGNENVFDIGEITNMIPSIKREKLYNIKDLKQITGSDPLVIFGACAGPYPFLGIDSECVVNVKMTG--DQVENGTHAHMTKSNDPECCHKMLPND--EMRFSFLANFFTSNGFKGEVLKIVCEVRKGPLSFSMCIREALVKHFGDEIIAIGGVIFIENGKVKVHVIKPSFMKKPSKSEKELENLVHFIELSPPLAGVGCIVSHNPGLNLRCQHFHLYSDHNQGGHYHNDTEPNTIKYTGYFGVSKQFTKID----------- -> ---------------------------------------------NIAAEGLGGRPRLLDVGGVPNLVPLVKREKLYDMSEFPQMCDMKGGLIIGAGAAPYTFLDRNAEMMINVAFSKSGEVQNQKTTIARTFDADNSQTLIHLPKE--ETKISLLGNLFLSEGKPGKVLRITAKKRTDSDNFVSCIRKTLVKGYPGQPVGLGGVFTVANGEVKTHVMP-DFSKVPLETDEDVANWLKFYNTKAPFTALSFLLSEDPGLDIRLEHSHGFNEAVEGGHYHTDTTPDTVEYLAYYNVAEYIYRIDQPKETHQVGRD -> --HNVPLHVPTDEQLCEVLSAALRSNFAEVEVNSAKCPDLTQPPWCLAVSGLGGDCRIADIGGTLNLEAPITRTLHYNLADVLQAIGKPSAHVMGPGAGYAGVAGINCELMATAQVVGTDGTDPKQDQCVETDPSS-TYLLEPY----SSLEVGPLMNLLISDGDPSSVIHVRVRGRIGESNLVSCMREALDAGFG-EVVGLAGVFQVLDGKVHAHVMP-GFPACYLRTDAQVQQWLHFFEMSAPLTCLSVMVSRQIELDLRVEHTHFYSDHGCGGHYHYDTTPETVVYEGYFVAAKTLHRVAQA--------- -> --REVLLEKPELAEVATVLQNGLKAHYADVTVEVVDCPDLTQSPYGLTASGLGGRPCIIDVGGIDNLFPRVNADKEYCLKEIAERTGRKDFHLVGAGSCGYSLIKCNSELVVNAGHDH------IKSLCARMVDNHKKICCEPY--K--SYRCSALANVFCSKGETGKVLKFHAKKRIGKPDFIACVQQVLKDKYGERPVSLGGSFQMLSGKAKVHVMS-DFTRNPIRTQEFINEWLKFVEAQAPMTFMTVCTSVSPGLEMRLTHTHGHSSPILAGHYHYDLSPDEIEYEGFFGVAESIVRVDQVNQTPNWH-- -> ---VLDLAPPSLDELKAVIENGLHDYFVESSVTITDCPDFKTEPYNLEGSGLSPDLRIVDCGGHGNFFPKFQRHKQFDLKKISKTSELPQGWIFGPGAAPRETVGVNAELVANANFNTN----KVNCYNGRLTPDGKGYLEGTH--S--DTCFKMIANLALCSDEAGRVLRISAKKRTGDGSFTEIIQKILASHYRNKLVCLAGIWRFEKGRGYFHIVP-DYPEKDFEKLDDIKNWLHFFELPAPMTMTTVIHSNDIGLDVPVEHTHGFSGRGHCGHYHGDVTPSEAVYDGYFLPATKLYRIDNTKH------- -> ---VINTLKPSNNELRSVIETALWKNFKNVQVAVSNSPDLSKPPFRMTSNGFGKKLTIAEVGGMGNLFPVLR-KEEYDIREICSLCDKKSAFVFGPGACPKSVMGTTGELVADVNLSTGMAARAVASKVTTIVNDE-CLPYKTTAID--STKFSLMANLAISEEGPAEVVRATFLVAP----------PTVSRAHTCSCVSLAGIFLLLRGQASAHIVP-DFPTGNFKSIEEEEQWLRKFTLKAPLVCTSVFHSYDAGHRLRMVHTHCYSDHNDAGHFYTDITPESAVYEGWFTAAEQVYRIDK---------- -> --KTCDLEPISLKELSTTLQDHLSKIYGHVKVSVVNCPDLSKEPFNLAGSYLGGKTAIADLGGIPYLVPVGYAAPIYPLIHLAKKMGFQDAHLMGAACVPFQITGSIADFMPNISYSTGKTTVNHGSYYSEMVDDK-KHIMRHLA----SDCVTVLANVFISENKPSKEIKIVASKRVDKESLTIAIRDILRIAYPEKAISMGGMFLARKGKINIHVMPNDFSKTPCDTEEKVNEWLKYFEASAPIVGLVTLHSKDPGFNFRDEHTHCIG-KGEGGHYHHDTTPDTIEYEAYLNIAQKIVRIDQPALNNE---- -> ---IHPITPPNLSEIADVLQNGMQPLFHDVRVDIASCPDLTTAPYNLAGVGLGGNTSLVEFLRREVYTPWQH--ITRDIRKVFTGS-IHDFFIIGSTFATKPTMPYYGHLIMNAMYTA-PMGIRNESRLIFKESRNGQTRIEKLTDP-NQMMYTYKGNFFISEGREGPVIRVRAKGRKKSTDIITSMQTVLYENYRNKLVALGGVLKMTNGRVGCNLIW-DEYRDRILPFPDFVKAQQCICLESDMVAVGTIINHQPQFEQRRSEFHCFNNYGAGGQFITDTTPDTTEYEGYFNVAENI--------------- -> ----RSLYIPSLEELSSVLQTGLRKNFKEASVSVCYCPDLTQPPFSLAAPGLGGNASIADVGGQLNMHKVNNNKYHFDIKVLSKEM-KGLPFYIGAGATKLSFRRDNSELIPNVDIKSN----INHSKEAYVAADGKGHLVEY---Q--STEFSSLGNFYACEGKRSTVLKIEARDRTGDLNIVTCMRQALFNHYGDKQIGLGGVLLVKNGKIRSHIMP-GFPPCDLPGTN--IEWLNYYEVSAPLTCLSVFVSADTHDNLRIEHTHFFSNHDDGGHYHYDTTPQQIHYEGYYNVAS----------------- -> -------------------------------------------------------------------------KEIFDLSKVPEWTELPDAFMLGAGAGPRHVEGINCEMMTNLQVTP--DGVNNQSYIAKVGTEDNKYIVKKVD-N--TTDCCLLMNLFVCEGKPSKVLEVKASKRTGPQNYMLCLRDVLAKHYGTQPVGLGGTFLMRKGSAKIHIMP-DYSDIPLESDAAVDAWLKFYEMKAPMIFMGYVISHDPDMDLRVEHFHGFSQHGDGGHYHYDTTPDEVEYVGYFNLGESMYRVDRPSVTHGIGRD -> --EKASLYVPELSQLADMLKESLRGNFETVETKVVQCPDLTK--WGLAAPGICGNPRIIDIGGVPNLLPKHHDTAFFTIPQVAEDVGLKGAYVYGAGAASSKVVGVNAELMPTEHVSEN----CRCSRYSKVLEDG-SHTMEKY--N--SSEFGLLANLIACDGKQGNVVEVRAKKRIGKDNFVTCMRTGLAKRFGTRQIGIGGVFKVKSGKVRGHVMP-DFKPTVMIDGPEVEDWLQFYEMGPDLTCLSVFLTGDPGLDLRLEHTHFFSQTNEGGHYHFDTTPDEVEYVGYFLPAPDVYRVANAFK------- -> ---VQSLNVPSLTEVKEVLSRSLPAFFEEVEVEVTPCPDLRESPYLSSFQGLSDGNVILDVGGVDNLLPRPNKKKLYDLSDLVRQAVEKPTCLVGAGAGPCHVYGMNSELICNTCITG-----SSTSKVALMIPQEETGKEKHEVKDDVSNKSSVLLNVMLTEGKPGEVLRIRLRGRAGKKDVPQCIADCLKAHYGSRPVSLGGLLVLKKGRARLHCMP-DFSKEPIRTPEGVDEWLRWMEGEAPMRFMFVATSADPGMDLRLVHTHGWGERRYGGHYHNDTTPEAVEYEMVCMTAGAIARLDRVTQTPNWKRD -> --ESYALSPPTLDELREVLAEGLNSNYEDVDVSVVSCPNLRQAPFGLVSEGLCGGTCVIDVGGVDNLFPKVNLTKEYCLREVAQQIGISEPHFLGAGSCGYSCTGRSAHRLPDSHGCSNAGLNENRSKCIVMDDDHVACCVRDY--N--EHRVSALANVFCSAGEAGQVLRVHVKHRKGEADFVGCIQRALRVKFGDRPVSVGGSFVMHKGTAKIHVMS-DFTQEPIMSQEFIKTWLKFFEGRAPMTFMFVCTSVDPNLSMRLTHTHGHNSNNMGGHYHYDLTR-EVEYECYLNVAEVVHRVDKQHQSPTWDK- -> --KTCDLEPISLKELSSTLQDHLSKIYGHVKVSVVNCPDLSKEPFNLAGSYLGGKTAIADLGGIPYLVPVGYAAPIYPLIHLAKKMGFQNAHLMGGACAPFQIIGLVADFMPNISYSTDTKTGKTKVVHGSQYPEDKKYVMRHLA----SDCVTVLANVFISENKPSKVIKIVASKRVDKESLTIAIRDILRIAYPEKAISMGGMFLARKGKINIHVMPNDFSKTPCDTEEKVNEWLKYFEASAPIVGLVTLHSKDPGYDFRDEHTHFIG-KGEGGHYCNDVTPDIIEYEAYLNIAQQIVRVDQPALNNE---- -> ---VRQLYVPDFKEVAGVLKNGLGKNFKNVQVEVVKCPDLSKPPYSLASPSLSVGA-VIDIGGVINMEFLQNNNKHYDMKQIVKDV--NLPFFIGAAASAASKANDNSELMPNANVKT----GVNKTKEAYVDKTG-NCCLEDY--K--STEFSSLGNLFACEGNAQDVLKIKVSVRTGELNFVTCMRQAINEYYKDKQIGFGGVFTINKGKFKSHVMP-GFPPCDVFGKD--IAWLKFYTVDAPVTCLSVVLSNDKHNGARLEHTHFVSTRNDGGHYHYDVTPETIEYEGYFTLANQFYRIAKA--------- -> --ETTPLATPILSEIAEALQNGMQPLFHDVKVDIASCPYLTAAPYNLAGVGLGGNTSIVEILPHGGNVSWYR--NKRDIQEILTTS-CHDSFAIGSSYATKPGMPYYGHLIVNATYRA-PMDLRNESRLVFAERPNGQTTIEKLTDP-NQMKATHKCTLFVSEGMAGRVIRVRAKGRKTRTDIITSMQTVLYERYRNKVVGLGGVLKMKYGSVACNLMW-DDYQEPMLPFDDFIRGQQCIYLESDMIAVGAIMNDKPELEQRRSEFHCFSNYGAGGQFINDTTPDMTEYEGYFNVAEK---------------- -> --ESAELYVPELKELAQMLETSLKGNFKTVEASVVDCPDLTK--WGVAAPGLGGNVRILDVGGVPNVNDPAYHDICFDIPTLADQSELKDAYVFGASAAYHGVVGKNAELMPTEHLDTS----CRCTRYAKVTDDG-GHTCELY--N--SDKIGLLANLMACEGKPGKVIKVHVKERVGEENFVTCMRKGLASELGKKFSGLGGVFKVKEGMVKGHVMP-GFKNTVMVDGPEVEEWLNFYDMGPDLTCLSVFLSGDPGLDLRLEHTHYFSQKKEGGHYHFDVTPKEIEYVGYFTPSPIIYRIANAFER------ -> --ESKPLFTPPLESLKEVLEKGLKSNFDEVDVNVVTSPDLMQEPFNLASEGLCGNPKVLDIGGVPYLVPLAQKNKIYDMKDYPKLTDFGATLIIGAGAAPWTYLERNAEMMPNLLVKS-DGSVVQKTHIARTHDKDDSYELLALPES--ETKMSLLGNLFLSNGQPGKVIEVKCKKREGEENFVSCMRKCVEKEFPDKSIGFGGVFCVQKGQVKIHVMP-EYSTKPLNSDADVENWLNFYQMDAAFTCFSVFV------------------------------------------------------------- -> ----RELYVPELTEIAEVFRKALSANFKEVSVSVEPYPNLCEPPYSLASPGFGGKTGIVDIGGVLNMEFLINNNKHFDLHEISNKT--NLPFFIGAGATKVSVIKNNSEWIPNANVKT----GVSLSKEAYVDNHG-NC--CQVDHP--STEFSSLCNLFGSEGTSGKVLHVVAHVRTGKLNFPACIRQALATHYPTQQVGVGGVFILKKGTFKSHVMP-GFPPCDVFETD--IPWLKFFEVKAPVTCLSVLLNIDKHGNARLEHTHFFSTADSGGHYHYDLTPEIVEYEGYFAPAQKFYRIARAQKPQQ---- -> ----------------------------------------------LPRPGLSGNPRVADIGGQNNLFPSPNLDKRYDLLSISELMDMKGGVLIGAGAGPFFDLGLNIELMPNIAFGASDRELRNCTRYAKVLDDD-SALCEGI-GT--STGCALMCNLLGCDGETGSLLHIKVKGRRGKLNFTEAIQKGLADVYGDRLISLGGVFVARSGKLKMHVMP-DFPGKPFKNRGEVEQWLRFFDMDAPMVCLTVLHSGDDKAGLRKEHTHCFGANRRGGHYHFDLDETTVEYEGWLNVAEILYKID----------- -> -----KLYVPELKELATMLEGALKENFDEVETKVVDCPDLTK--WGLAAPGIGGDPRIIDIGGVPNLLDPTYHGETFHIPNIALDVGLKGAYIYGAGAASSKVVGVNAELMPTEHVSKN----CRCSRYSKVEKDG-SHIMEKY--D--SSDIGLLANLVACKGEKGPVVMVRVKKRTGKENFVTCMRVGLEKALKNRQIGIGGVFKVVEGKVRGHVMP-DFKPTVMVDGPEVEEWLQFYEMGPDLTCMSVFLTGDPGLDLRLEHTHFFSQKPEGGHYHFDTTAENVEYVGYFIPVPTVYRVKNAF-------- -> --KTTDLFVPELKELAGMLKTALEKNFETVETAVVKCPDLKK--WGLAASGICGDPRIADVGGIPNIMDYEHHKEVFHIPTIASQCDLPGAYVFGAGAASSKVVGQNAELMPTEHVKA----CCRKSKYAKVLEDG-SSTMEDY--H--SSDFGLMANLVACKGEQGDVVMVRAKVRKGKENFVTCMRRGLLNILEQYHIGIGGVFKVLKGKINAHVMP-DFKKEKIGEPGWTDDRNIHYEMGPDLTCMSIFVTGDPGLDLRLEHTHFFSQKKEGGHYHFDTTPKEVEYLAYFIPVPKLYRIDNPYPR------ -> --------------------------------------------------------------------PAAWRERTYNFNHVAKQTDVPGAHVLGACAGSKHYVQVNSECIPNIRTEDDKEQFRNETHIAKIDPSDGSCVLMHYQNELQAAEFTLLGNLFLSEGKQGKVLKVSVKTRTGSGSLTTCMRKTLEANFE-TPVGLGGPFVQLAGKVRYHIMP-DFSSCLLNSDADVENWLTFHEFGAPFVNMATLISKDPGLDLRVEHTHGYSKNKTGGHYHYDTTPQEIEYLGYFSPAEFIYRIDGPTETHMIGRD -> ----KALEVLPLEEIAKVLENGLKKNFSDVNVSVVECPDLREEPWGLAAEGLGGATRVLDIGGVPYLMPSVKREKLYDMKDYPELTGLKSGLVIGAGAAPWPFLGRNAEMMPNIMVNE-DKSVIQETHIARTFDEDGSYTTQKLPAT--ETRNSCLGNLFISEGTPGKVLKIHCKKRTGAKNFVTCMREALVEEFPDKSVGLGGVFNIVAGKAKIHVMP-DFSPCPLNTDEEVNKWLK---------------------------------------------------------------------------- -> ----------------------------------------------------------------------------------------------------------------------EHNPPVNGSYFARVNPEDGRCRLEKYSEKHHDFGCALLANLFASEGQPGKVIEVKAKRRTGQLNFVTCMRQTLEEHYGNKPIGMGGTFIVQKGNVKAHIMPAEFSPCPLTSDEQVNKWLNFYEMKAPLVCLLVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDTVEYLGYFTPAHFLYRIDQPKETHSFGRD -> -VEKLELSSTTLADLASVISSGLRNSFSRSSCTVTITADLRLPPYHLAAPGLSGSPRVVDIGSPPSPPTQPHQKIRPPLH---RQTDRPPAAAHRRRRGPFHTVGKNCELAPNIAYSDGGRKVVNRTHYTKLEPGSGSLVPQCLQIEEESTGFALMANLYGSQGLPGEALHITATARTGSASFTDAIQDAIREHYGHPLISLGGVFVLKRGKANFHVMP-DFPGPELDSDEAIAKWLRYFDFEAPVVALSVLHTCGEELGLRVEHSHCFSETGRGGHYHYDVDETVVEYEGWFNVAEWVYRVDRPG-------- -> ---------------------------------------------------------------------------------------------MGAGAGPWPHLGTNSEMMTNLAING---EQHNKSRLATVVDDKPLRQLHTLPQD--ETNCALLSNFLISRGHMGPVLRVKCSKRIGPDNFVSCMRKAIHRRYPDQSIGLGGTFIIAEGRAKLHIMP-DFSSCPLLSDDDVNNWLHFYEAKAPLIGLSVFISHDPGLDLRVEHSHCFSLHGDGGHYHEDVTPDTIEYVGYFTPALKMHRIDRPTQTHNIGRD -> -------------------------------------------------------------------------------------------LVIGAGAGPWPHISRNAEMMPNLYVGA-DLSVRQETRITRTHDEDGSYSTHKLPAS--ETRNALLGNLFISDGEPGEVLRIDCRGRTGDKNLVTCMRETLEAASPELALGLGGVFSIRQGQAKFHVMP-DFSPCPINTNEEVNQWLKFYTVSAPLTVLSVFVSRDPGLDLRVEHSHGWGDGAQGGHYHYDTTPDTVHYTGYYNLAQTCYRIDRPVETHQVGRD -> ----------------------------------------------MTASSMGSSLRIAEVGGVSNLFPTPQKNKYYNLKELAETCELSDGFIFGPGGGPRHIIGTNCEMVADACFEKG--KEKVAVKMGVVTTKV-PQGHEMITT--EKPEFCLMANLGVCKGIPTSVLKIKARKRLGDLNFPEAVRRAIATHYKDQLVSCAGIFLLKGSKARIHVMP-DFPSGSFASAEEMEKWLKIFEIDGPIVAASVIHSKSVDNKLRLEHTHCYNKH-EAGHYYCDTDPESVEYEGYFAVASAVYRID----------- -> ----TRFLSPPLNELAAVLQKGLENNFDEVSVKVVDCPDLRSKPFLLAERGLCGSPRAMDIGGVPYLIPTPHMEKIYDLSQVPSIAELSDTLMVGAGAGPSHAVGKLSEMIVNMNADE-LGHICNHSRICKIDDESGKYVLHRL---ENSCDGCHLTNLFISEGKPGKVLEVRAHRRRSDDDLVGAMQKSVGSHYGSQPVCIGGVFVLTKGKARIHIMP-GYSDVPLTSNEMVDEWLNFYDMSAPLSAVGYFVSHDPVSKLR---------------------------------------------------- -> -------LEPEMEKLAEYLQVEFNKFYNEATVKVVNCPDLRKAPFHLVAPGLCGNTALLEVGSLSNLFPFPRMEKKYDFISFLETSGRSNDFIIGASLYPSS-NGHMGELIMNASFSEEGMRVKNRSYVAFLAQDHENVKLDIL-NDYNRVKCFLHGNFFISEGKPGRVLEIHAKARREDKELTKVIQHTLQKYYESTLVGLGGTFVVHNGLVRHHLMP-DIGQINCSDESRIRNWVKTRILTTPLVAVGTIVNKSSDLQLTTNHFHSFSEPLVGGHYYTNVEYGSAEYLGYFCPAKKLYRLDNDEICH----- -> ---KINLVVPSLDELKSVLHDSMVKNYESVSIDIVECPNLRESPFRMTGSGIGNNLRIAEVGGIPNLYPHGT-KKIFNLKKVCETCELPEAFVFGPGAGPFDAIGHSSELVADANLIK--SQFKIANKVSWIVSSANGYTMSTT--D--STDFEITANLAISDGCAN--RKICATKRIGELGYAESIQRAIESYYGHQLVSLAGLFLLHKGDVYMHILP-DYPVSPRKQDEKF-----FRESERKTTGXSVVHSHDNDGKLRVEHTHGYNENKSGGHYHIDTTPEIAQYEGYFAPAHCIYRIDK---------- -> ----------------------------------------------------------------------------YNFDTVASLVDLPGAFIIGAGAGR--LCTINCELMPNIVTTSDCTHGDNKSRAAMICPDDGILMIKQY--D--LNEFYILGNLLACEGKQGPVIEVKVSKRSGKENFVTNMRETLKAHYGDKPVGLGGTFLIESGKAKLHVMELDYYTVPLNSDADVDSWLKFREADAPLVCLSVLISHDPGLSLRVEHTHCFRQFNEGGHYHYDTTPDEVSYHGYFVPAEYMYRLDRPP-------- -> --KRHRLYQPSLGSISLAITEGLQKNFKQVTVKVVKCPDLREWA-NLSAKGICGNTRLIDAGGVPYMFPEMQATVNYCMQDLIHACDMKAGLVIGAGAADPKVIGKNGELVPNLKVPS----GANHTHYAKMENAGNDVPVCRT---YASDFCGCLCNLFVSDGCNDSVLYIKAKSRIGKLNFTNCIRESLQNVKGDKQIGMGGVIKVSQGRIKGHVMP-DFMKECVDIMIAVDNWLHFYECGPNLVMMATLISGDPSMHLRVEHTHFYTLVNEGGHYHYDTTPDEIEYEAYLNTAEFVYRVDDA--------- -> -VKKVKLHIPTEADLLFCLEPALENNYQQVEIDFVECPDLSQPPYNLASEGLCGSPKLAEAGGVPYLIPGPANEHVYSYRDVCKIVGLPDGLAIGATCSSPESVKSCAEVMPNTSAE------KNLTHCARVNNDGESYDCKLY--G--SNEFTTLGNLCISKGQRGRCMKIKVKNRIGNGSLTICLQDALKEKFK-LPVGMGGVFVLGKTKTKVHVMPQRFSQKPLKTSKKIDEWLQFYETTAPITHLATLISRDVDFSFRTEHTHCFSKHNQGGHYHYDVGDKEVEYEGYFVFPDTAFQIDWP--------- -> --KERSMKTPTLSEIAEVLQNGMQPLFHRLKVDVTSCPCLTKEPYNLAGVGLCGNTAIIELGEKPTENVSDWKDRTCDIKSVLKTN-CSDSFVIGSSYATKPHMPYYGHLIMNATYRA-PESFTNASRIVFIETGNGQRRIETVTDP-NQLTCTHNGCFFVSEGRPGNVVRVRAKGRKMITDIITSMQTVLYESFGTETVALGGVLRMRYGQVACNVML-DEYPDEKLQFVNFYFQQQYINLESDMIAVGVIFDDLPILDEERSEFHCFSDHGTGGQFISDISPDTTEYEGYFNVVKK---------------- -> --ERAPLHVPSLEEVQEGLARELQDVYKRTDVSVEECPDLQK--WGLAFSGICGSERLLDVGGVPNLLDPAKHGISFALEDLCKCGGLPNGSVLGAAAGDANFVGKNSELMPCEDVDAK----SRSTHVAKLDDGG-QCVLQAY--D--HGRMGFLGNLFLSEGKGGKVLKISVTSRRPDGDFTAALRSALGRAFPGRAIGLGGAFKMISGRFKAHVMP-DFKETQMEDGPEVNAWLKFFEFGPGATFLSTLLTSDPKLNLRLAHTHFFNETGQGGHYHNDTTPEDVTYEAYYSPAHYVYRIENAYD------- -> ---EIDVTPPSKRAIANILKDGLKEHFKEVSVEWVDCPDLRKKPFNLAAPGLCGKPALMQVGGLANVYPWQQIHKTYNIKHLLTEFGYNEKLVIGAGMCKNPLTTLNCELYMNTLYSPRMISVFNRSRTLFYLSKT--CRTGPYKIHNNLHECSMYGNFFISGGKPGQVIKVYAKKRIGSLDFISAMQSSSCYGRTKYMIDLGGTFVVNNGKVWHHLMP-HKAATILRDFRSIHQWLRYRCMPTPFTAVGTFSNRIRVLNITKQHFHTFSSYNTGGHYYIDALEKATEYLGYFCPAKKFYCVDPVNVN------ -> ---VYPLESPTIDEVADALRDGLAKVFKKIDVDVVDCPDLRQAPYLCSKPGLGGKGSVVDCGGCALLYPKVDITKEYDMRQIASIV--DNYHVGGAGACAYSVTGQNGELAINCADEG-----DPHTACGIVCEDS---LPEKKNYH--SYLSGPLCNVFKCSGAPGKVLRVHAAARMDPSDIVETMKSILETAFPRDVLGLGGVVLVKKGKVMIHVMH-DFTVKPIRSQKFISEWLRMKEADTPFTNYTVFVTNPPTLDLRPSHTHGFND-KVAGHYHYDTTPLRVDYECYLQLADNIYRVDRASQEPDFD-- -> ------------------------------------------------------------------------------------------------GAGPWPHMNTNCELVANCLLTE-EKIIKNLSRVGIVGKNG-EALVKILPNS--ETRCCLLANFFACKGEPGPVIEIRCKGRKGTKDFITTLRTILEHNFN-EVIAMGGVFVILKGKAKQHVMP-DFSETPLNSDEDLNNWLKFYEMPAPLVAVGTFVSKDPGLDLRIQHFHSFG-ENEAGHYHYDTTPDEVEYLSYLLPANVLHRLDKPEVTHNIGRD -> -VTKHPRDPPPLDELAAIIERSLLCNFSTASVSVVQCPDLRHAPFNLAGSGLSGNTRIADIGGQQHLFPQPVLDAKYSMLSLAKDMEMSSAFILGAGAAPFQDIGQNAELAPNLSWEANSLNVESGTRVIKISQDN-SPKCEQL--P--STNCALMINLFGSNGETGAVLKISARTRTGEENFTNCIRNGLRDAYGSRPISLGGAFLLKSGSAKFHIMP-DFPAEPFRDRQQLKEWLTYHVFDAPV-------------------------------------------------------------------- -> ---KMGLFQPDLEHLAESIRKALTENFESVTVTVVSSPNLQE-WCGLAERGISGNCRLVDLGGVPYMMDPKYHHITYQLPDVVKTCDMTGPLVIGSGAASPTVVGKNAELMVNALIPGEV---------------------------GPSEETGCLMNLFLSEGKPGKVIYIKVNKRKGRLNFTNTIREGMKSCKGEHQVGMGGVFKVNKGKIKGHIMP-DFCKKKMDEKEEVDNWLRFYEFGPHLLMLSCLLTDDPSLHLRLEHTHFYSDTHEGGHYHYDITPDEIEYEGYFSLAEKIYRVEDAY-------- -> ----VDLPLTTLSEVASALQSDMNTFFREVNIDIVRCPYLTTKPFNLAGIGLNGNPYILNVGQIERFFPTPQPDATWNIREILSNS-CRDAFIIGAGYAATPYMPYNGHLIMNATYRA-PATFTNASRIVFADANNEQRRIKTIDNP-DHMMCSFMGNFFVSEGKEGNVLRVRAKRRESNLDIITIMHDIIYRHFQNRFVALGGVLRMRNGRVAHHLLA-EEYPSQISTFDDLIKRFQCIPLESDLIAVGSFANLPPTFENRFYQFNSFSDYGAGGNFISDTTNYMTEYEGYFNVARKLYSV------------ -> --TKHLRDPPPLDDLATVIERSLLSNFATASASVVQCPDLREAPFNLAGSGLSGNARIGDVGGQQHLFPQPVLDAKYSVLSLAKDMEMSPTFILGAGAAPFQDIGQNAELAPNLSWKASSLSLENGTRVIKINQEN-SPKCEKL--P--STNSALMINLFGSDGETGPVLKVSARTRTGEENFTNCIRNGLRDTYGSSPVSLGGAFLLKSGSAKFHVMP-DFPPEPFRDRQQLKEWLSYHVFEAPVV------------------------------------------------------------------- -> ----FPVRRDHIVEIARELKRGLQPLFGFVDAKVVECPNLTRKPFNLPRSGISGENTIACVGSHDYILPSISCRKQYDLMDVANACKVRAGEILGGGTGPYPTTGHPCEMVAELCYCN-GSISCNRTLHAYSDKSGS--APNLIKAT--DTKFHSSAQLFVSEGNEGWVIEVIAKRRLCEGSIGKFLHQALQSRYGDEPMALGGVFLLEGSGAKYHVLS-ELPNEPYHTFPDLKSYLKCFEMKAPIIGMGTVLSHDPDLGLHMHSFHIYNERNVAGHLETDTDPEAASYRIFLHPASHICRMDKP--------- -> ----------------KALQKKLLENFAEAQVDVVDCPNLAEDPFYLNKEGIGGSPSLISCGTVTNFVPKLKLERTFNLKMFPPLAGLESASFIGTGMYHCHESGYLPETTVNASISK--GELDINKTVGYMDKISKKHILKSAPIT--LAEFPCLLDLLFSKGEKSKVLRVHCSKRTGEFSLPSILRNGLRTHFPDKLIGLGGTFLVKQGMATCHVNH-LSENDQFREEEFFKDSCTFINMSAPLVAVGEIISQDPGLELRLEHFHCYSNHGDGGHFHYDTTPESVEYLGYFSIAETLYRIDYPEN------- -> --EKAKLYVPKLSDIKIALQDGLSNNFRKVNVSVVDCPDLTK-FVNLSSKYICGSTKIADVGGVPYMDGEPYCYTTYNIDNIIKHCDMKNACVFGASAASSFILEKNAELIPNTKVPCGP----INTKYASLDNNPDTPYVSHY--P--WNQTGCLANLFLSDGKPGKVLHIRCEGRTGDINFTNCIRESLKNGYGNGEIGLGGVIKVLKGQIKGHIMPNHFPHVKIPNET---EWLRYYKCGPNLAMFSVLMTDNPNNHLRLEHTHFFNDVNEGGHYHYDLTPKSIIYDAYFSVANDIYQIDNAYNN------ -> -----PLDVPSLTELQEGLEEQLKENYESVDVSVEECVDLTL--WGLAFPGLCGSESLVDVGGVPNLLDPAFQRLAYPIEEICVCAGVPNGCALGATAADANFVGKNAELIPCESVGD----RSRTTQTAMLDDDDERPELIAY--D--HGRIGCLGNLFISEGKPGRVLKIRVAKRSERGDFVAVLQNCLVKAFPTKHIGLGGVFRLDSGAVKAHIMP-DFKKTVMIDGPEVESWLKFFEFGPGGTFLSTLLSSDPQLNLRLSHTHFFNATGEGGHYHNDTTPKDSQYTAYFMPAKYIYRVENA--------- -> ----------------GVLEKALLKNFKEASVTVVPCPDLTREPYRLAAPGLNGQTAIADVGGTKNMHYLENNKHHFDIKDLSHQI--GLPFFIGAGATKLSFRKDNSEMMPNLDVSK----GVNLSLEAYVGKDG-VGQLVDY--P--HTEFSALANFFVSEGKSGPVLKIKAKHRIGKLNIVTAMRQALVEHYGDKQIGLGGVLLINNGKIKSHIMP-GFPPCDVNTGQ--IEWLTYYEVSAPITCLSVFVSHDKHKDLRIEHTHFFSNRKDGGHYH----------------------------------- -> --KTCATFVPPMDEVCKALEKNMAGDFETVECKEVWCPDMREAPYHLAAQGICGSPRLADVGGPPYLVPTVQRDKLYNLKDIAEEVGLPGATFIGAGAGSSRLTGTNCELMPNSNLAT----GEIKTHFAKMKDG--KPELERY--M--SNEFGLLANLLATEGKRGKVLQVKATGRIGDKTFVNSIRLALAKEYGEKPVAVGGVFIIGKGKAKLHVMP-DFSTTPLTTDAEVDAWLHYYE------------------------------------------------------------------------- -> ----IETLKPSNSELLPIVESALKSNFKDVTVEVGPCPDLSVEPFSMTSSGFGQNLVIAEVGGPGNLFPKINKEKEFDLKEICNTCQSPFSFVFGPGAGPWKVVGRNCEMVADANFAT----AKVATKIASLPPGYPPYKMGVI--D--SPKFSLMANLAVSEPGPGEVLHCKCSVRIGKDNFPETIRKALAKHYGKRCVSLAGIFLLGEGEAKLHVMP-DFPGCQFSSTEEVSLVFK---------------------------------------------------------------------------- -> ----IDLYVPDKTELAIVLQNELSTDFEEVKVEWVDCPDLTQEPFNLAAPGLCGDTALLDIGGIWNLFPFPIKDKIIYFQSILEKLDRTQSLIIGGGLRTERPTNLLGELIMNVLAANETMTVKNKSRFALIKLNRKHFSLKFVTDP--NPYCNIYGNFFISKGLREQVLKIHVKHRT-GRDFIVSLQHAIKRFSKSQLMGFGGTFIIKNGKTIQHIIR-NYWEVPIRKKKDIHNCIKYLKINSPIVAFATFVSSDRKFDVYLNQWHVHANSNDSGGYYHETVPNNTEYLGYFSPATKLYRINPVSEFDEM--- -> ---RMVLDVPDLMEIQAGLEEQLKESYESVDVSVEECVDLRR--WGLAFPGLCGSESLVDVGGVPNLLDPNFQRLSYPIEEICVCAGVPNGCALGASAADANFVGRNAELMPCESLRD----RSRTTHTAKLDDNDERPELVAY--D--HGRIGCLGNLFVSEGKPGRVLKIRVANRSELGDFVGVLQNCLVKAFPTKHIGLGGVFRLDSGAVKAHIMP-DFKKTMMTDGPEVESWLKFFEFGPGGTFLSTFLSSDPRLNLRLSHTHFFNTTGEGGHYHNDVAPKDCQYTAYFMPAKFIYRIENA--------- -> --TTLSTKVLPLSQIAQVLQDGMAKKFREVKVDIAACPCLTRQPYNLAGVGLSGNPSLLEIGGHANFVSNYDYDPTWKVQNMLASG-FFDSFIFGSGYAAKPNMPYNGHLIINATYRA-PSNFTNASRIVFAEASNGQKRIEMLTDP-NQMLCSYMGSFFISDGRPGLVLRVRAKDRISTLDIITIMQNSLYEHFGKHPIVLGGVLRMWNGRAVYSLMSEEYPQRQIHEFSDFNKWFQYHEMKTEVAAVGILTNRKPDLEQRRNQFHFISDYAASGEFIGDTTPDETEYEGYFNLAKKYI-------------- -> --ESASLYVPELDQLAEMLEESLKANFEIVETAVVDCPDLQK--WGLAAPGICGNPRLIDVGGVPNLLPKYHGTAFFSIPNVAETVGLKGAYVYGAGAASSRVVGVNAELMPTEHVGKN----CRCSRYSKVLEDG-SHTMEKY--E--SSEFGLLANLVACDGKPGKVVMVRAKKRLGETNFVTCMREGLAKRFGTRQIGLGGVFKVKSGKVRGHVMP-DFKKTVMVDGPEVDEWLNFYEMGPDLTCLSVFLTGDPGLDLRLEHTHFFSQTNEGG-------------------------------------- -> -----------------LFQRKLADYFAEVAVAVVECPDLKKEPFHLASSGLSGSPAACDVGGVPNLAPLARTDKEYSIPRICHSLGYGQGFFVGAAAGPFKCVGVNSELMPNVLVSGGKATVVNETHCAKLADNEKGYQLLKMVDQ--AAEFCLLGNLFLSEGKPGSVIQVKAKRRVTETNFVTAMRNILKEEYGCKTVSLGGVFLLKSGRAKLHIMP-DFSKAPLCSDDEVNNWIYQQNKDRPL-------------------------------------------------------------------- -> ---------ISIEEVAVAIKEGLTDIFKNVKVGVVDCPDLREAPFFCCKPGLGNPHEVVDCGGVALLYPKVDLSREYDMRQIATIVDEHHH--SGAGSCAYSVTQQNGELAINCSEEG-----EPHTECGTVGEDT---MPERREYH--SYLSGPICNVFKCTGAPGKVLRVRAAARMDPSDIVETLKSILEKAFPHSILGMGGVVLVKKGKVMIHVMH-DFTVKPIRTQKFIDDWLRMKEAETPFTNYTVFVTNPPDLDLRSIHTHGFND-KMAGHYHYDTTPLRVEYECYLQLADSIYRVDRAPQEADFQ-- -> ----IDLYVPEQTELATVLQNELSTDFEEVTVEWVDCPDLTQEPFNLATPGLCGDTALLDLGGISNLFPFPLKDKIYFQNILQKVLDRTQSLIIGGGLCTKQSNELLVELIMNASFSNGTMTVKNKSSFASIEITQKYFVLKSLTDT--NPYCNIYGNFFVSKGLREQVLKVHAKHRT-GRDFIVALQHAIKRFSKSQLMGFGGTFIIKNGKTIHHIIK-NNWKIPIRKKKQIRYCIKYKNQTSSVVAFATFISADRKKDIYFNQWHVHAKSNDGGGYYHETESNNTEYLGYFSPATKLYRINPVPVFHEM--- -> ----------------------------------------------------------------------------------------------------------------------------------------SGYLTRRLPPT--ETRTALLGNYLLCDGRPGKVIKVVAKKRIGESNFITAIRETLKNHYGEKVVGMGGTFVVRAGRVKHHVMP-DFSAAPLCSDSDVDAWLHYFEMRAPITHVGTLVTGDHGLDLRVQHFHGWGEHGDGGHYHYDVTPASVEYEAYLTPAASVVRVDAPATTHAIGRD -> --TQLRLSPPFLEDIAQTLAKALPSNYITSSATVT---DLRQAPFKVTGEGLTGSETAADIGGQVDLLPQPYLHKTYSLIETAKLMGLSPGAIIGAGAGPFLVDGTNSELAHHLSWGNGFDSVTNLTRAAQLRKEGSALPVC--CPLSGSTDSGLMMNLYGSKGLPGPVIKPSARGRQGDSSCADFIRQSLAKAYGDLQVSLRSVFIIKSGKAKFHVIP-PFPKVKFRNQEHLDGWLSYHTFGGPMIRLAVLHCGDPEKGIRLEHTHCYSERGEGAHYHYDLQDSEVEYERYFNTIKTFHQINY---------- -> --ERIPLHQPNLHDLANFIRSNLKKHFLDVKVTVTKSPDLSKYPWSLSSPGISGEPTIVDVGGEHHQVFDYANKLVFTLEELAESAGADEAYFLGAGAAPRSSVGCNGELIPIDNIYTN----VRRSQLATVKINAMGVAESSALTPYNSSEMGFLANLLMTEGKTGEVLEIHVSKRISNESFTECIRQVVAKEFENEPIGFGGVFRVNKGKVKTHVMA-DTGGKTL-TAEEVQEHLKIFEIGPDLTAATVFLTKSPKNKVRLEHTHLYNQKTKGGHYHGDTTPKEISYTGYFTLAKSLFLVDRD--------- -> ----------------------------------------------------------------------------------------------------------------------------QETRITRTHDEDGSYETLRLPAS--ETRNAVLGNVFICDGQPGQVLRIKAGVRRGEKNFVTCMRECLNSAYPDKAIGLGGVFCIQKGTAKFHVMP-DFSPCPINNDDEVNKWLKFYSMSAPLTVLSVLISSDPGLDLRVEHSHGWGEDSQGGHYHYDTSPDTVQYEGYYNIAQACYRIDRPVDTHKFGRD -> -VEKKHLHTPPLSEIADYLNEGLKSNFQDVKVEVVDCPDLTQQPFTLADKGLNGNPKLVEVGGPPFLLPLVQKDKVYDVKDIAKLAHSDPAFVIGAGAGPHPYIGKNCEGVYNLKINN--DTIEQHTRISKVVEGSEKPVQEILPNT--ESRVALLANFFVSEGRPGKVLKVFARRRIGADDFIASIRKTLVSAYPEQLVGLGGAFLLKE-------------------------------------------------------------------------------------------------------- -> ---------------------------------------------------LSGKAIICDVGSFDYLLPVPKKDKHYDLLDVFRSAGVAAGAVIGAGAGPFFLTGSNSEMVINISSES--GVVKNGSLFGLYDKENNKPLLTKA--D--NTKFALLGQMFMCEGKPGPVIELNVSGRIQDGKFDAMIREALHVKYGNNAVGLGGVIVQEKGKSLYHVLP-EFSQEPIDSGEKLRNWIKMFEMESPVISVGIAVSHDPHHGLRLEHFHCFNNQTNCGHCHFDTYGPTVSYRCYFSIANHLLRIDQPSKS------ -> --EVKDLYVPPIQDVAEVLNKSLRSNFEEVNVEVVDCPDLTQQPFTLASGGLGGNPKIIELGGNPYLLPVVHREKLYDLKGIAKLVESDPAFIIGAGAGPNPYIGVNCEGIYNLKISN--GSVNQQSRISKVDKNDDKSEQETLPNT--ETRLALLGNLLVSEGKPGKVIKVHAKKRIGDDNFITSIRKAVENAYKNELVGLG--------------------------------------------------------------------------------------------------------------- -> --TVIPLPTPSLDQLANMLHQAAAANFANVSAKVVDCPDLRE--WGLSFKGLGGNPKLADVGGVPFINDPNYHDVTYELHEIMRQAGSAEGCIMGSAAASRSIVGRNAELVASLDSTA----GQSGSFFAKIQDGK------QVADHYYSTTVGGLGNFFISDGTAGKVVELRVSKRTGDLNFVTALREGLAKQVGSAHIGLAGVFTQPSGSFKYHVMP-KFKKTRMVEGQEVADWLHFFEAPGQTTTVTTFLTGDPGSNLRLEHSHFFDKRKIAGHYHYDTTPDTAEYVAYLVPAASMHRISN---------- -> --ERIALHVPELKELAEVIANSLRPVYRNVSTRVITCPRLTDESWSLPSPGISGSNAILDVGGEHHQVEAYANELSFGLEEVAVAAELRGWYFLGAGAAPRGCLGCNGELIPFDNLHS----GTRNSQLATVERDEGDERPGLCKYN--SSTMGFLANVMSCEGKQGDVIEVKASVRTSSESFTECIRRGIASGYADEPIGLGGVFKVVKGRVKVHVMA-DTAGRVFTDSSQVQEYLKMFTIGPDLTCATIMISKQPSGKVRLEHTHLFNACTEGGHYHGDVTPQEVEYVAYLVPTEELLLIDKR--------- -> ---QIHLFIPEGAKLAAVLQNELSTDFEEVTVEWVDCPDLTEEPFNLATPGLCGDTAIFDVGGVSNLFPFPQENKIYFFKDMVRTFNRLDTLIIGGGLTKVSEEKLLGELIINASFDERTAVIKNKSRFAFLKTLNQKCKLIPL-IDNTNPKCHMYGNFFFNNGLREQVLKIQAKNRV-SRDFTVALQRAISRFASGDLMGLGGTFVVKNGKTKHHIIQ-NDWKGPIRKSTEIRKCVQFCEMPTPVVAFATFLSADRKIFLTRWHAHSYSAF-GGGHYHETKQNSNVEYLGYFSIATKLYRIDPVPMFN----- -> --TTHPLPPTSLSNLISPLLTSLKQNFTDATISLVPCPNLTQPPFHLAAPGLSGHEAIVDIGGPAYLHPVPDFSKKYDLGRIVASLSSGEELAIGAGAGPFHIVGQNSELIPNFYISASGNVTKNLTHYAKIDPSTQTCIAGPVPGA--STAGALMANLFLSDGDPGPVLRITARNRIGDKSFTEAMRMGIEER----EISMGGVFVVEGAKVWAHVMP-DFCGERLE-DAEVGKWLRFFEWGGELVFLSCFHGVDFGVGVRVEHTH----------------------------------------------- -> ------LHKPSLEEVAEVIQKGLAKNFTTAQVRVVDCPDLSAAPFDLADKGLSGTPRILDVGGPDFLKPFPQKDKKYTFAQVSELGELPGSFIVGAGAGPCHNVGTNCELICNVKLGK---ETINKSHIVKVNEEDGSYSIHEE--K--SGEFSLLGNFFLCEGKQGKVLEIKAETRTGSENFVECLHKTLTNHYGDKPVGIGGTFLLQKGKAN---------------------------------------------------------------------------------------------------- -> -----------------------------------------------------------------------------------------------------------------------------------------NYRLDKC--K--YPEFGLLGNLFISEGKPGKVIEIIVEKRLGKENFPESIQKILRENFPNKPISLGGVFIIEKGRTKLHIMP-DFSPEPLRTNDDVDKWLRYFDMDPPLICLTTLHSIDPGLDLRMEHTHCFSDHNQGGHYHYDITPDIVRYTGYLQIVEAIYRIDRPK-------- -> --EEKPLYVPPLSELQNVIQGALNTNFANVSVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLLPLVQRDKLYNITEITRQIQGPGKFAVGAGAGPWPIRGSNCEGIFNLSVSE-KNELTNGSYTATVRGEKEECVLEKIPHS--EPRCALLLNLFLSQGQPGEVIKITAKQRTGEQNFIECIRKGLEEYYGDKVVGLGGIFLIKK-------------------------------------------------------------------------------------------------------- -> ----INLDVPKQTELATVLQNELCSDFEEVTVEWVDCPDLTQEPFNLAAPGLCGDTILLDIGGISNLFPLLTEDKIFKFTNILQKLDRIDNLIIGGG--QIKQSNTLGELIMNASFSNEMTTVKNKSNFAYIEMPQKKFVLESLTDP--NPYCNIYGNFFVSKGLREQVLKVHVKHRT-GRDFIFALQHAVKRFSKSKIMGFGGTFIVKNGKTIYHNIK-NNWRIPITMKNHMHYCIKYREVTSPMVAFATFVSADRYKGTYFNRTHVHVKSNADGGYYHETEPDNTEYLGYFSPATKLYCINPAPVFHEM--- -> -VQKVPLFVPGLKDLASALETTLTPHFLNVSARVVRCPDLTSSEWGLAAEGLLGENKLYDVGGEHHQVKPYANRLAFGLEEVARAGNVTEAYFLGAGAAPRASVGCNGELIPIDNLYGN----VRKSKLATVEIDSHGIPRAALQ-QYRSSKMGFLANLMSSHGDRGDVIEVRVSRRISTESFTDCMRRGLSETYRSNPVGLGGVFRVLNGQVRTHVMA-DTQGKVFTESAQVQEYLKMFTMGPDLVAATVFISDQPRSSVRLEHTHLFHSETTGGHYHGDVTPSEIEYLAYLVPNHELIIVDRI--------- -> --TRHRLFVPKLSDLATMIEETLTPHFQTAQARVVPCPDLTKKGWQLASKGISGSNKLFDIGGEHHQVKKYANKLSFTLEDIAGAAGLTDSYFLGAAAAPRSSVGCNGELIPIDNLID----GVRLSKLATVNETDP-TGLRVSLSPYHSSEMGFLANLMSSEGSPGQVIEVRAKVRLGDASLTDCIREGLAEKLKLPPLGLGGVFKVVSGQVKTHVMK-DTGGRHFHHSSEVQEYLEIFTMGPDLVCTSVFLTGEPSDRVRLEHTHLFKDLQKGGHYHGDVTPDEIEYVGYFVPNEELLVVDRDVEAVH---- -> --SKTRFTSPSLNELAAVLRSGLMNSFDEVNVEVVECPNLKSKPYLLSSEGICGSPRALDIGGVPYLIPSPCMEKIYDLSKAPSWSELSHTLMVGAGAGPSHVVGKLAEMIVNVSLDE-SGNVENQSRICKIDDKTGKHVVQRV---ENSTDCCHLTNLFASEGKRGKVIEVRASRRKPDDDFISSLQKAVKSRYNSQPVCVGGVFVLTRGRAHIHVMP-RYSDVPLVTDAMVDQWLKFI-------------------------------------------------------------------------- -> ---SAKFNNPSLEILAEALKKGLKANYQEVTVEIINCPNLRE--WNCPSEGISGNERIIDVGGEPYMHDKQFIGTEFDYEEIAKNIGSEKSYALGAGSGAMSCLGHCGELIINENLITN----ESNSIIAQVNKNK-ECVTKKY--T--EKKHGGLANIFFSDGKIGKVIKIKLKKRIGKGSLPQAMRSALFENIINRHVALGGVFRVLHGGVKSHVQP-DYEDIKYEYYKCTKDFLQFYEVGPKLQCYSVLWTGDPTGNLRETHFHSYNNKPEAGHYHFDVTPNDIEYECYFNIAHEVFRVNNIYKE------ -> --------------------------------------------------------------------------------------------------------------------------VQKTTMARTMDDADETYKLLQLPKE--ESKMSLLGNLFLSEGKQSQVLEIKCRCRSGKQNFVSCINAILKEAYPDKCIGIGGVFCATKGKLKIHVMP-KFSEVPLKTDKDVENWLNFYEMDGPFTCLSVLVSNDPGLDLRLEHSHGFNAQGQGGHYHYDTTPDIVEYTAYYNIAEVCYRVDRPNVTHMVGRD -> -----------LNELIEPISNSLLKLYENVEIKVINMPDMSSPEFKLAAKGLCGHTRLADVGGVPYMNDPKYHDVTFQLTDIVKVCGLDKALVIGAGAASPTVVGRNAELMPNTLVPGNNENKETESKEESNNNE-NEVPFVGI-YP--SEETGCLANLFLSDGKQGPVIYLKVSKRKIDLNLAVCIRDALNEFREKEQIGMGGLFKVSKGKVRAHIMP-DFANFVLEKPEQVENWLKFFDMGPELAMFSTLITGDPSMHLRYEHTHFHSKTHEGGHYHYDIE-KDVEYEGYFNLAEFIYR------------- -> -----TFANHSLEDIASALKKGLSENFKTVEVEVEDCPNLRD--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYQEISKMINSEKSYALGAGSGAMSCLGHCGELVINENLITD----ESRSIIARVSPDK-KCIVEKYT----AKKHGGLGNIYYTDGKQGKVIKIKIKGRSGNGSLPQAMRSSLSNNLNNEHIALAGVFRILEGKVRSHVQP-DYKDIDPKQMKCVKDFLQFYEVGPKLQCYTVLWTGDPGLNLRHTHFHSYEHDRDAGHYHFDVTPDEIEYEGYFNTASEVHRVNNIYKEL----- -> ----EKFDTPSLDKVAEALNLGLKENYKEVNVEVVDCPNLKD--WGCPAEGITGNEKIIDVGGEPYMHDPKFIGTEFDYEEISKKIGSEKSYALGAGSSAMSCMGHCGELTINENLITS----ESKSIVARVDKNK-KCIVQKY--S--ARKHGGLSNIYFSDGKKGKVIKIKINIRTGKGSLPQSMRSTLIKHLKNKHVSLAGVFRILKGKIKSHVQP-DYKDIKVDYYKCTKDFLKFYEVGSELQCYSVLWTGDPKLNLRHTHFHSYNNEKDAGHYHFDVTPKEIHYEGYFNISKEVYRVNNIYKE------ -> -------------------------------------------------PGLSGKPCIVDVGGIDNLFPRVNCEKEYCLRECAERSGRKNFHLCGAGSCGYSLIKCNSEMVVNAGHDQ------IKSLCARMVDNHTKICVEPY--N--SYKCSALANVFCSKGEAGKVLKIYVKRRIGEPDFVGCVQQVLKDQYGEQPVSVGGAFRMISGKAKVHVMS-DFTQNPIQTQEFIKEWLKYVEAPAPMTFMTVCTSVSPGLGMRLTHTHGHSSPKIAGHYHYDLSPDEIEYEGFFGVAEAIVRVDQVSQDP----- -> --EKAQFTKTSLEQISEALKKGLQKNYKSVEISIVDCPNLKQ--WDCPAEGLSGNQKIIDVGGEPYMHDKKLIGAEFDYEEIANKIGSEKSYALGAGSGAMSSLGHCGELVINENLITN----ESRSIIAQVDENQ-KCKSSKY--T--ARKHGGLGNIYYSDGKPGKVIKIMIKGRSGTGSLPQAMRTALKENLSDNHFALGGVFRILNGKIRSHVQP-DYDTIDPKQMKCVKDFLKFYEPIGPFQCYSILWTGDPKLNLRHTHFHSYKGTQDAGHYHFDVTPEEIEYECYFNIPEEVHRVNNIYKE------ -> --EKADFKEISLDKISEALQSGLKKNYHQVEVSVEDCPNLKE--WGCPAEGISGNERIIDVGGEPYMHDPKHLGAEFDYEEISKKIGSEKSYALGAGSGAMSCLGHCGELVINENLITS----ESKSIIARVGTN-KECIAEKY--T--ARKHGGLGNVYYTDGVKGKVIKIKIKGRSGDGSLPQAMRKALSDNLPNEHIALAGVFRILNGQIKSHVQP-DYADIDAKQMKCIKDFLQFYEVGPELQGYSVLWTGDPNLDLRHTHFHSYTKENVAGHYHFDVTPNDIEYEGYFNIAKEVHRVNNIYK------- -> ---------------------------------------------------------------------------------------------------------------------------------------------------------SLLGNLFLSNGEGGQVIKVSCKKRTGGDNFVSCMRKCLEKEFPTESVGLGGVFCAQKGQLKIHVMP-EFSSEPLKSDSDVENWLNFYTMDSKFTCLSVFVSRDPGLDLRVEHTHGLNEKCQGGHYHYDTTPEEVEYTGYFNLAEYCYRVDRPKVTHMIGRD -> ---SAKLFVPELEELATMLQTALKDNFETVETEVTECIDLTK--WGCAAPGIGGNCRIIDVGGVPNLLPKHHKTAIFQLPTVAEQVGLKGAYIFGACAASHLVVGVNAELMPTEHISKN---CR-CSKYAKVVEDG-SHIMEAY--D--SPEFGLLGNFVACEGKTTPVVKVRVKKRKGEDNFVTCMRKGLAKALEESKVGIGGVFKVVSGKIHGHVMP-DFKKTVMIDGPEVDEWLNFYEMGPDLTCLSVFLSGDPAKDVGKHFTLSFS-------------------------------------------- -> -------CQPPLKYVAAVLQAGLRENFAEATVTVEECPHIRQAPWGLAGPGLGGKTRVMDIGGVPYLMPSVQRERLYDMKDYPRMTGLDEGLVIGAGAAPWPFLDRNAEMMPNLFVKA-DGSVLQETHIARTHDKDDSFETIKLPKE--ETRNSLLGNLFISSGEPGPVLKIHCKGRTGPKNLVTCMREILAEAWPSETLGLGGIFRIVKGKAKFHVMP-DFSPCPIPVMQRLTS------------------------------------------------------------------------------- -> -------------------------------------------------------------------MPSVKREKLYDMKDYPELTDMKSGLVIGAGAAPWPFLDRNAEMMPNLMVKE-DKSVIQETHIARTFDEDGSYTTMKLPAT--ETRNSVLGNLFICEGTSGKVLKIHCKKRTGDKNFVTCMRQTLVDQFPDKSIGLGGVFNIVAGKVKIHVMP-DFSPCPIDTDEEVNKWLKFYEMSSPFTVLSVFVANDPGLDLRVEHSHGWGK------------------------------------------- -> -IERKSLDRVPLEELAQVLNQSLKDNFDYVNVEVVDCPDLTGHPFTLAKPGLDGSTKLVEIGGVPYLLPLVKREKIYDLKKIAISVKSDPAFIIGAGAGPHPYAGVNCEGIFNLKIEN--GTVDQQTRISKVDPNDKRSFQSTLPNS--ETRVALLANLFFSEGKPGKVLKVHTKKRTGSQDFIASIRRSLVNAYPNK-------------------------------------------------------------------------------------------------------------------- -> -------------SLIQAIENELKQVYKQVNVRLVPNNDLSAKPWNLAGSSLGTNGVFCQLGGAKNVEYKQGHSIRFDISSVLDQLHIKNKLVIGPGAGDLTHLTINGELVFNMTLNQYNKVITQRSYSSIVSKEE-QPYQSSY-E---PKTCGPFQHIMISSIKSAVLIEIDVQERLTDNNFISVIRRSLKQ-YSKEPMALGGIFRVEKGTVKAHIMP-DFLDEDLTTKQQVDQWLKFYDMQAPLNCLSVLLTEDINNGFRLEHSHFFSDHGQAGHYHFDITPKEVHYHGYFILCDEAIIVDP---------- -> -------KKFKLEEISNALEKGLSKNYDSVKAEVIDCPNLRN--WDCPSEGMSGNQRIIDVGGEPYMHDPKYLGTEFDYFEISKMIGSERSYALGAGSGAMSCLGHCGELVINENFITK----ENKSLIARVGKDK-QCIVEDYT----ASKHGGLGNVYYSDGVKGKVVYLKIKKRIGKGSLPQSIRAVLSENLKKDHIALAGVFRVLNGKIRSHVQP-DYKDIKHEYPKCTKDFLQFYEVGPKLQCYTVLWTGDPELNLRHTHFHSYEHKNDAGHYHFDVSPDEIEYEGYFNIAQEVYRVNNIYKE------ -> -IEKAKLKKIDLNQVQKALQLGLSDNFKEVKVEVVDCPNLKD--WGCPAEGLSGNEKITDVGGEPYMHDKRFIGTEFNYEEVAKEIGSGKSYALGAGSGAMSCLGHCGELIIDDNLIT----REIKSIIAKVGNNK-ECITENY--N--QRKHGGLGNVFYSDGKKGKVLKIKIKGRNGKGSLPQAIRAALIKHLDDNQIALGGVFRIHNGKIRSHVQP-DYEDIKHEYYKCTKDFLQFYEVGPHLQGYTVLWTGDPKLNLREEHTHFYDDKKISGHYHFDVTPDEIEYECYFNLAQEIHRVNNIY-------- -> ---SAKFNNPSLKDIVNALKKGLKANFQDAAVEIVDCPNLKE--WGCPAEGISGNEKIIDVGGEPYMHDKRYIGTEFDYEEISKKIGSEKSYALGAGSGAMSCLGHCGELVINDNLIT----GVSKSIIAQVGKNK-ECVSNEY--S--ERKHGGLGNIFFSTGLRGKVIKIILKKRIGKGSLPQIIRSSLIESIDNAHIALGGVFRVINGAIKSHVQP-DYEDIDMKLMKCTKDFLQFYEVGPNLQCYSVLWTGDPQLDLRHTHFHSYDDKKKAGHYHFDVTPNEIEYECYFNIAHEVFRVNNIYKE------ -> --HRVKLHVPSMQKLASMMYRTLSSNFREVSVSVVQCPDLRD--WGFASPGLSGTNTIVDVGGEHHQVQSHANHLSFHLEELAIVIAEEDSYFLGAAAAPRASVGCNGELIPIDNLRD---H-VRNSKIATVEVSPDGHERAVL-DSYDSGEMGFLANLMASDGKTGPVIEVRAAVRLSEESLTQCLQQGLKDQMALAPIGIGGVFKVTRGRVKTHVMA-DTGGKTFTHSSEVKEYLKLFNMGPDLTAATVFLSRQPSKKARLEHTHLFSDMKEGGHYHGDVTPTEIEYLAYFVPNHHLLMVDRT--------- -> --EKAKFTEYSLDKISDALQSGLSSNYKVVEVSIVDCPNLRD--WDCPSEGISGNQKIIDVGGEPYMHDPKFIGAEFDYEEISNMIGSEKSYALGAGSGAMSCLGHCGELVINENLITD----ESKSIIARVGKNK-ECIAEKY--T--ARKHGGLGNVFYTDGNRGKVIKIKIKGRSGEGSLTQAMRKSLSDNLKNDHIALAGVFRILNGKIRSHVQP-DYKDIDPEQMKCVKDFLQFYEVGPELQGYCVLWTGDPNLNLRHTHFHSYTKENVAGHYHFDVTPEEIEYEGYFNTAEEVHRVNNIYKE------ -> ----IDLFLPDKMKLAAAVENELSTSFGKVTAEWVDCPDLTQEPFNLAAPGLGGDTAILDIGGISNVYPEHIESKIYHFENIFKHLNCNQNFIIGGGLSRRLSDNHLGNLIMNATFSTENRMVKNKTLFAFVDEADVKFTLEMLTNP--LPKCHMYGNFFVNQGLREQVLKVEAKERY-GRDFIDALQHAFSRIYPDKLTGCGGVFMVKNARVVHHVMQ-NNWCSLFYNKLTIKESLRYWSVKTPVIALTTFLNTDRKFDLFLTRFQVHSSNNCGGYYHKAEDDEAIEYLGYFSPATKLYRIDPVPMYTE---- -> --EHAELYVPELKRLSEMLEKSLSNNFESVEVKVVDCPDLRK--WGLAAPGLCGRPRIIDVGGVPNLLPKHHGTAFFDIPTVAKQVGLPGAYIYGAGAASSKVVGVNAELMPTEHVSES----CRCSRYSKVLEDG-SHMMDKY--E--SSEFGLLANLVACEGKPGKVVKVTAKKRTGDDNFVTCMRVGLKKQLDD-SKGIGGVFKVTSGKVKGHVMP-DFKPTVMIDGPEVDEWLNFYEMG----------------------------------------------------------------------- -> ----------------------------------------------CASQGLGGHTALCDVGGVPFLLDPEWQDVYFELRKILNVVGMPKATALGAAAAWNGRIGVNGELMPYASVNS----GTNTSHFSIVNKDG-DCECNHYPYL----EQGPLSNMFLCDGTQEDVIKIEVEVRTGDENLVSCIRNGLIETFNSRQIGMGGIFIVKKGKVKMHVMP-DFYPSMVDGDQVVKEWLKYYEVGPNLLCLSTMLTGDPDMHLRLEHTHFYSMPTVGGHYHNDVTPEIVRYIGYFSPAEYIFRV------------ -> ------LYQPSLQELQKLLTVTLKKSFEDVVVKITSCPQLTKEPFNLAANGLHGNTAIIRCDS-------KTTQRKWNMNYFLQNF-PYDSFLIGGGFGAKPNLPSNGYLIMNATFSR-PEQINNASRLAYVRSLTDSGIVEIMKEP-DQMTCCTIGNFFMSEGRPGPVLEVQAKKRKSPPNIISIIGKILYSYYGNKLVGLGGVLLINKGEMLVSVISNKIPENQIISSNDLLNRVRAINCTSNITAFGTILGSKATFKLYPRHFYTFSENNVGGRFAKDVTPDETEYVGYFNTAEYLYH------------- -> --------NHSLEDIASALKKGLSENFKTVEVEVEDCPNLRD--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYQEISKMINSEKSYALGAGSGAMSCLGHCGELVINENLITS----ESKSIIARVGSN-KECIAEKY--T--ARKHGGLGNVFYTDGVRGKVIKIKIKGRSGEGSLPQAMRKALSDNLKNDHLALAGVFRILQGKIKSHVQP-DYADIDPKQMKCVKDFLQFYEVGPELQGYSILWTGDPTGNLRETHFHSYTKENIAGHYHFDVTPEEIEYEGYFNTAE----------------- -> -IKEKPLYQPPLQEVVDVLSNGLANTFATVSVSVADTPDLTQAPYNLTSPGLTGDPKLVEIGGPPYLLPLVQRDKLYDLALLAKHLQRDPAFIAGAGAGPWPHIGVNCEGIINLSIEN--GKVDQGTRIVSVEPVTGLYLQRRLPNN--ETRTALLGNYLLSEGKPGKVIKIVAKN------------------------------------------------------------------------------------------------------------------------------------------ -> -------------------------------------------------------------------------------------------------------VGVNSELMPNLSWEG--EEVRNLTRYARIDEGG-GCVCERITEGKGSVDCGLMANLFGSDGAPGKVLKIVVSTRTGDKNFTDTIRDALKDVYGERLVSMGGVFVIKKGKAKLHVMP-DFPNAPFKDRGDVERWLRYFEMEAPLVCLSVFHSCDPGLELRMEHTHCFKEGRDGGHY------------------------------------ -> ----------DILEFYQNLESTLQKYFDSVSITLLNSSTLLETDFQLPFKSIGRNHKIVDIGGVPNLLNPEFHNISYSIDDIVQSIEIDSAAIFGASAADAVYLQTNGELMPVESYGSG--DRTIGSFSAIIDQSENGCCCKLQRYN--HSRIGFLGNLFVCEGQAGPLLKIIASKRKDEINFVSAIRNCLKELYPEEGIGLGGIFTMKAGRFKAHVMP-DFKDSVMEDGPEVNEWLEFFEFDSNATFLSVLVSQDPSMNLRLEHTHFYNETKQGGHYHHDTTPETVIYEGYFTFADSIYRIENA--------- -> ---QADLCTPGLEELAAAIERGLEAEFREVHASVSSCPDLRQPPFGLAIAGLGGNPRLADVGGVPNLLDPEYHHLSFSVSDIVRCTRPETAAVLGASAADARFLGCNGELMPVECLHSSRTDTPLRSTFSATLASDQSCSLQPYPHD----RIGFLGNLFISDGVAGDVVKVQARGHRSAASFMVAVRSAVAAAFPGKAIGLGGVFTMDGGEVKAHVMP-DFKATVMEDGPEVNAWLKYFRFDGSAAFLATALTRDPSLNLRLEHTHFFNATGVGGHYHNGFPAVDASYIAYLLPAAAVYRVENA--------- -> -----------REKLVETIEKTMKEIYQNVKIRLVSSMDLSGAPWHLASKNLGENGFFCQLGGAKNVEMKKGHHIRFDISSALDQLAIRNELVIGPGAADRTCLSINGELIVNLTMNQYNKVVRQRSYSSIVSNG--QAEQNSY--E--SQTCGPFQHLMISSVKPGILFEIDVEQRLSDNNFISVLRRSLKE-FSTKPMGLGGIFRIEKGTIKAHVMP-DFLDEDLTTKDQVDQWLKFYDMNAPLNCFSVVLTDDINKGFRLEHSHFFSEHGQAGHYHFDTTPKDVRYRGYFLVCTEAILIDP---------- -> --------------------------------------YLSKAPFNMTSRGFGNGLRIAEIGGPSNLFPKLHKEKAFDLNEVCATCDAPHAAVFGPGAGPWPVVGVNCEMVADANLSQHNLYIQTATKIAYIEENSSNKYQTKI-ID--STKFSLMANLAVSENDPSEVVHFKCSIRTGQLNLPETIRRAIAEHYTDKPVSLAGLFILHEGEAKLHVMP-DFPSCPFNNTDEVI-------------------------------------------------------------------------------- -> ---VADLYDPGLEALGLGLKQNLQSEFEHVDVCVCSCPDLRQDPFGLPFTGIGGDPRLVDIGGVPNLLPRFH-DLSFAIADIVRCTRLADQAVLGASAADANFVGCNGELMPAEAIMNYPTSADASSFSATIK--HDACHLQPY--P--HGRIGFLGNLLISRGSASRVLKITASGHRTASSFMIAVRTAVAAAFPNRAVGLGGVFTMQSGTVRAHVMP-DFKTTVMEDGDEVNEWLRFFRFESEATFLTTTLTQDPCLNLRLEHTHFFNARGIGGHYHHDSAEKYAKYVAYLVPARKIFRIENA--------- -> ----------------------------------------------------------------------------------------------------------NAEMMPNLYVKK-DKTILQETRITRTHDEDGSYSTIKLPET--ETRNALLGNLFISDGKPGEVLRIDCRERIGEKNFVTCMRETLADTWPELAIGLGGVFNIGEGRAKFHVMP-DFSPCPINTNEDVNQWLKFYEVSSPLTVLSVFVSRDPDLDLRVEHSHGWGDGKQGGHYHYDTTP------------------------------ -> -----------------------------------------------------------------------------------------AQLVMGPGAGSSKILKVNSELIANVNLKSK----SLLSKYAIVNEKG-DYVMGDY--K--STEFGILAKLLVSEGNTGKVLEVKASNRTGNLNFVTCMRKSLEENIKDQSVGLGGVFNIKTGKIKAHVMP-DFPSCDLLNQKQVDDWLKFYEMKAPLTCHSIFINNDLNKGLRLEHTHFYSDHGDGGHYHDD--------------------------------- -> ----------------------------------------------------------------------------------------------------------------------------VASKITTLAENK-SVPFETKTIN--STKFTLTGNFIVTAEGPAEVVHIKCSERTGKLCFPDTLRESLEQRYGKECVVLGGLFRLLRGKARVHIAP-EFPEKPWKSMDEVEHWYQPFVVSAPLLCASVMHSYDPGFKLRMQHTHCISDHNDAGHFENDATPEEAEYEGWFTAAEKMYRIDE---------- -> --RTAPLLVPPLEEVRGALAEALSEDYREAAVDVVDCPDLKT--WRLCQSGLGGKGTLVDVGGEPFNHTLYNQKVRFDISKVCASFGRGKGAVLGAGACCAEVIGHWGELTVTAALAN----GANGSVSARVLEDK-SCCAEAY--K--SLLHGGLMNLYVTEGLPGKVLRVHAKARTGERSLTQTLRRGLQASFPQAAVGLGGAFKVVQGKVKSHVQP-DLCACSVEELKCTKPFLQFYEGGPDLVCVTSLWSKDPHMRASGEHTHFFSLKSEAGHYHGDDPTSEIEYEGYFTCAGEIARVR----------- -> --KSKQLWQPDLADLASALQQELDKHFNHAKVRVVDCPDLTK--WGCAACGLGGNPVLVEGGGEPFNHDHYNKEVHFKLDRMAEQVGHGPGYIQGAGACAAQLRGHLGELVPCLTIGK-----QNMTKVARVESKSRAAIVEE---D-NTLMCGGISNLYMCKGERGKVVEVEASGRKGEASLTQVLKTGLGNLPGGKQVGLGGVFRMETGTAKAHVNP-DMEVLDPTQMKCVKDFLQFYDFPAPLLCFTCLWTDEVSLNLRGEHTHFWREPEAGGHYHGDTSPEKVSYRGYFAPAGTIFRL------------ -> -----------------------------------------------------------------------------------------------------------------------------------------SYELVALPES--ETKMSLLGNLFLSNGEGGKVIKVNCKKRSGSDNFVSCMRKCLEKEFPTESLGLGGVFCAKKGQLKIHVMP-EFSTKPLELDSDVENWLNFYTMDSNFTCFSVFVSRDPGLDLRVEHTHGLNEKCQGGHYHYDITPEVIEYTGYFNLAEY---------------- -> ----ITRHQLSLHELAEVLESALPKNYVTSSTTVVDCPNLPQSPFSLACEGLSGCQVIADIGVQPSLFPQPRLDEQYSLIVCVRLMGLDPEAVVGAGAGPIHVHGTNSEIAPNLSWQGGFGNVDNLTRAARLVTTLAGSRTRICCPYSDSTECLLMMSLYGSMGLPGPVLKVTARGQRGENSFTEFMRSALQDIYA---------------QTQFHVMP-SLPHSPFKSQAALDGSLSYYDISAPMVCLLVFHSADPQLGVRMEHTQ----------------------------------------------- -> ------------------------------DVVSVVCP-LTR--FTFPVXXICGKTRIAEVGGVPYLIPLVNKKKVYDLNIIAKEINLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHNPPVNGSYFAHINPADGGCLLLSHSQKHHDFGCALLANLFASEGQPGKVIEVKAKRRTGQLNFVTCMRQTLEKQYGDKPVGMGGTFIVQKGKVKAHIM------------------------------------------------------------------------------------------------ -> ------------------------ENFAEATVTVEECPDLRQAPWGLAGPGLGGETRVMDIGGVPYLMPLVQKEKLYEMKDYPKMTGLKEGLVIGAGAGPWPFLNRNAEMMPNFFVKE-DGSVLQETRIARTHDEDDSFSTIKLPKE--ETRNSVLGNLFISSGEPGPVLKIRCKGRTGPKNLVTCMREILAEAWPSETLGLGGIFRIVSGEVNT--------------------------------------------------------------------------------------------------- -> ----------------------------------------------------------------------------------------------------------------------------------------------------GAARCGLLANLFLCEGKAGDVLKVVAKGRVGAASVVTIMRKAVAEAFGG-EVGLGGVLRLVGGKAKLHIMP-DFCAGGLHSDEDVDKWLKFYEVEAPLVLMATMVTGDMGLDLRVEHTHGYG-ESMGGHYHGDLGGEEVEYEGWFNVAERMVRVDRPVVTHQIGRD -> ---SAELFVPPLDELAAAFTSGLARHFATVEVDVVDCPDLSTPEWDLARPGLCGRPRLVDLGGVPNLLHPAGNGTRFDGADVASKVGLPGAFLLGAGAASPRLVGANAELMINEVS--RW----SEPVAQTLLGEGAPSCCSRC-AT--GAEVGLLANLLACEGAPGKVVRVRVAQRTGSTNLVSAMRAALLEHFGDKRIGMGGAFRVVSGRVKAHVMP-DFPCVHMSEAGDVARWLRFFEMGPSLTCLST--------------------------------------------------------------- -> ------------------------------------------------------------------------------------------------------------------------DHVEXGTHVHMTMSDDAECFHKSLPDD--EMRFSMMANFFSSNGFKGEVLKIVCEVRKGPLSFSTCIREALAKHFGDDIIALGGVILIENGKVKIHVIKPSLAKIPIKSEKELGNWLHFIELSPPSVGVGCIVSHDPGLNLRLQHFHLYTDRNEGGHYHNDTEPNTIKYTGYFGVSKQFIKID----------- -> ----EPLFVPEMEEVRKALITSLSEDYRESSVEVVDCPDLTT--WKLCQKGLGGKGTLVDVGGEPFNHAFYNKKVKFDISKVCASFNQEKGAVLGAGACCADVIGHWGELTVTANLAD----GSNGSVSARVLEDK-KCCAEKY--D--SLLHGGLMNLHVTEGLPGKVLRVRAKARVGERSLAQTLRRGLQVFP--KAVGLGGTFKVLQGKVKSHVNP-DQCALNYYSVEELKPFLQFYEGGPDLVCISSLWTKDPAMHLRGEHTHFFSLKSEAGHYHGDDPTAEIEYEGYFVVANELARV------------ -> --QKSPLLVPELKELAAVFETILKEIYSEVSVKVVDTPDFTRAPWNLAAVGIGAKPDLINIGGVDNFKNPKNNYKKFNFKKLGETIGQPYAFISGSAGASSDYVGDNAELIANLNLDS----RLNKSKYAQVVKNSNNPGYKLY--DHNTLEFGLLGNFFASDGKAGKALEVKVSKRKIEQNFVTGLRLGLLKKYGDKPVGIAGIFTIKNTQIESHIMS-GFPTTELLTSDDTKKYLTIFNFDAPATVTATIISSDPKLKL----------------------------------------------------- -> --ETISLFQPDLSQLINVLTDGLQYHFEIVEVKCIKCPNLTDKPFNLVGNGLSGNEAIIGCFSTDDELRRATETATWDLKDFAMHF-CNKLFFIGGGYAGMPNLPFNGTLVMNATYSA-PQQINNESGIVFKDTNSNRIRMETLNDP-DYMICSMNGNFFMSEGRDGTVLEVRVMKRRKKGDIINLMMNSLMAAFNDCSIGLGGILIMKKGSVTHQVLPDNVEMSTLKTPFVLSNHIEYHNSQPFLISLGTIVAVSTAYQNRLHKFYSFSNNENGGQFFNDISSNDIEYIGYFNAAKELFNI------------ -> ---VIENHVPSLDELKEVFIKSLTENFETVTVDITTCPDLSKPPFNQTSSGFGENLRIAEVGGPGNLFPGFHIDHQFDITTIGKVCELPEASVFGPGAGPWPVVGQNSEMVADVNLKT----GRSATRIAEIKPGNGNKKYLQRSID--QPKFSLMANLALSNAKSASVVHFKVSVRKGEKNLTLCIRDGLQKHFGDK-------------------------------------------------------------------------------------------------------------------- -> -VEKFPFHVPRLEELAGVLQNGLKNNFADVQVSVVDCPDLSKEPYTFPVKGICGKPRIAEVGGVPYLMPLVNREKVYDMNTVAKQIDLPGAFILGAGAAPFQTLGINAEFMPIVQTESDHKPAVNGSYFAQINPADGGYLLEKYSGKYNDFGFALLANLFASEGQPGK-------------------------------------------------------------------------------------------------------------------------------------------------- -> --ERFAFHVPSLEELAGVLQKGLKENFADAQVSVVDCPDLTQEPFKFPAKGICGKPRIADVGGVPYLIPVAKTEKIYDLNAVAKDIELPGAFFLGAGAASSRITGGNAELIPIVQTKSEKKPAVNGSYFAHINPADKGCLLEKYSSKYTDCEFGLLANLYASEGQPGK-------------------------------------------------------------------------------------------------------------------------------------------------- -> ------------------------------------CPNLKN--WGCPAEGLSGNQKIIDVGGEPYMHDKRYIGAEFNYEEIAKLIGSEKSYALGAGSGAMSCSGHCGELIIDDNLITK----ENKSIIAKVGKNK-ECITEKY--N--GRKHGGLGNIFYSDGKKDKVLKINIKGRSGKGSLPQAIRAALINQLNNNHIALGGIFRILKGQIRAHVQP-DYEDIKHEYYKCTKDFLQFYEVGPNLQCYSVLWTGDPKLNLREEHTHFYDNKSCSGHYHFDVTPDEIQYEGYFNTADTVYRVNNIYKE------ -> -----------------------------------------------------------------------------------------PSYLIGPGAGSAQIHGVNCELMCNCKIDGRSESLQFRHKVALINWKN-KFILNPC--F--ASECGPLANIFASTGAEQQVIKIDVKSRKGPMDFVHCLRSALMQYCEEQAIGMGGVFQILSGSIKAHIMP-DFCNEQLAVEGDVQRWLRFYEAKKALTALSYFVTHDPQLGLRFEHSHFFEEGGCGGHYHYDTTPETIHYVGYYVVAKLLYRVSQPAA------- -> ----------------------LLKNFAEVKVEIVASPDFTKQPFNLAAPGFGGRPTLVEVGGTSNYNTQIQKQKLFDIKTIVENLNYTDAFVTGAASGPWPFLQKDCDVAINVVLNK--QKSATSSYLITLDKNRGKIVCQALPLS--ETRFAVEGNLFLSEGKSGKVLKVYAKKRIGEYSFIASLRKSITDHFGKKLVGIGGVFVLKTGKTG-ELFP-NFLEEP---------------------------------------------------------------------------------------- -> ---------------------------------------------------------------------------------------------------------------------------------------------------------APVANVFCSKGETGKVLRVYVKKRIGQADFIACVQQVLKDKYGNRPVSLGGSFKMMSGKAKVHVMS-DFTQNPIQKQEFIKEWLKYIEAEAPFTFMTVCTSVSPGLDMRLTHTHGHSTPMVGGHYHYDLSPDEIEYEGFFGVAESIVRVDQVSQTPDF--- -> ----------QVGQVAEALQKGLKSHYTSATVTLDSYPAVSKWTGGKIQRG-CANVSLYQIGGGQNLFDPSRHGVAFDAEDILKITERKGKFFFGPGAVDSRVVKTNAELIAFWETEN-AKVTHIRSKSAKITDVSKSFQLVE--YA--STAFGGLAAFTHCQDKNETAIRIKVSGRITKLDFMSSLRQILLDAFPDKSMGIAGIFTMPSGTFNAHIMP-EFSSANLT-LAQFTDRLQFFEFEGEAVFLGHGVTNDPKFHLTPTHVHFWNTSMNGGHYHYDVTPDQVEYEGYFFVASKLFRIADP--------- -> ------LDQPDLEELRDLLDQKLRGSFRDFRVNVVRCPDLTAHPYSLASQGLCGHPEVIQVGNFEHMHDPHIEILPWHISDLIDNC-CEGRFIIGEGLLR--DIFTTKELMMNMTYAR-KRVLDNNSYGISVNDK--RIVSKRLPDS-YPAVFDLYGNFLVCGGLQKNVLEVRAKKIDSDVNILQLIRNALCQRYHNSNVGLTGVLLINKGSIEAAVVPPAFMPTSLRRINETEDFSIRYNIPAPLAVHTTMFNFNELPDDEMYVVNEYSNERMGGSYRKDITPHAMEFVGYFNVLNKLHRVH----------- -> ---HLALYTPDLKDVAEAVTKGLQENFESVEVKIHDCPKLNE--FNLPVHGICGNARIAEVGGVPYLYTKKHQKTEFSINNICTAAGIKQGLLFGTATPDASVENKNGEVVVNLHLNNSKEENKNDNEADSGNDDQKNEHLIITPY--TAKDIGCKANLFICNGKNEPVLYVKVSKRTGKLDVIEALREALKMVKGTTQIGVGGVLRVRKGKVKVSVSNPEYVELDYTKTENIEKTRQVHEIGPDLVMFTTFLTGDPKYHLTLASTGCYYNVNQGGIFVES-ASNEVEYEGYFVLAKYVYRVEDAYY------- -> ---HCKLYQPKWKEIQKAVSNGLQKNFKNASVEVVTCPDLKK-KWGVCDKGLCGNTRLVDIGGVPYLFHPSYQRKTFEVPDIVKTCNRNTPLVFGSCAGSYSVVGKNNELILNTSVPG-----GKNSKYAKITDNNKNDKNEK----KPSEQIGCLGNLFLCDGKIGQVLHIKARVRTGKDNFVTCIRESLKDIKGENQIGLGGVIKIHKGKIK---------------------------------------------------------------------------------------------------- -> ----KNIPPPSLDEIRMVLETGLRKNYEEAVVEIVDCPDLSKEPFKLAAKGICGGTCLADVGGVPYLCPGPARERVYNLDHTATQVHAPGGLVIGAGAASKHDVGVNAELIMNIRTSGGEAERKNETHCARVDPADKKALLLHYEKDLKSADFTLLGNLFISKGERGKVLKVTAKKR----------------------------------------------------------------------------------------------------------------------------------------- -> -----------------ILTHALSMNFSEVAVECIDCPDLRQ--YRLVAPGLCGNPAILEIGSLSYLFPQARLDKKYYFKNILRQLNLTSQFIIGAGNHSYPPNYDHSELYANFMLSRGSMGVQNASNALWFGGKEEELKWRYVCET--NPMCAIQGNFFVSQGEPGNIFRINAVNRTGPLDFVSSIQMSLKRMRQPHLIGLGGIFTTSDDNAILHGIPGKRNATEFYTMNQVQQWLKYKTITEPIIAVGTIMSE----------------------------------------------------------- -> ---HLALYTPDLKQVVNEVTAGLQANFADVHVEIHDCPKLNA--FNTEVHGICGNTRIAEVGGAPYLFSANHQKQSFSVTDICRAAGVQKGLVFGAATPDPSVENKNGAVVVNLHL-NNE----EQKQQEQQQQQQQDKDVSLVTQQYTAQDIGCSANLFICDGNDDAVLYVKVSKRTGALSIVEALRTALKNVKGTTQIGVGGIIRVNKGKVKAYVSNADYVELDHNNQAAVDDTRQMFEIGPKLVIYTTFLTDDPKYHLALQSAACYHDVDEGGVFVESATDDEIEYEAYFTLAKYVYRVEDA--------- -> ---EKSCHVPELGFFISALRTKLKDYFEEVTVQCVDCPDLTQPPYRFVAPGLCGNTGQLITGKFATMYPLPQSEKIYNFKKILRKIKRNKNFLLGSSLCSMAPQEVMCTVFINLLFSPNRKTREKLSLVYALDPIEQNYTFSSCIINNPDPECVMCGMCFISEGQPGQVLKIHVKKCINKLGFTAALHQSLREIKGNSPLGLGGTFVMSGGNVTTAIMP-KFPPNPLDNVEIIEANFRKNVATESLVVAGAVTSEYN-P---YLTFCTFNQYEACGMFDEKNSKDVTEYLGYFSLIENIYE------------- -> ---------------------ALASNFAQAEVTVVDCPNLTEAPFKLAGAGLGGKSAIADVGGVNNMEYVANNNKHFNIDKICESVEIPGGFVLGAAATKCSASKDNSELMPCVHVGG----AKNNSKEAYVDKATNQAVLADY--P--HHDVSSLANLLICEGSSDPVIKVRAAIRTGELNFVTCMRKALTEHYPEKQIGMAGSFIIEKGIFKSHIMP----------------------------------------------------------------------------------------------- -> --AELPLHCPPLEELADVFRAAAATNFQHVDVDVVDCPDLTLEPFKLVGEGLNGNPTLVDIGGVQYMAPMPQHSKVYNLIRVCEDIGMPTAFVIGSGAASFKHIGYNCELIANVNLAN----GKIASRTIRVNADS--VGVCEL-YE--SVEFAMFGNFLACDGRPGKVL------------------------------------------------------------------------------------------------------------------------------------------------ -> ----YGVHEVSMEEVAKILQNGLKDCFKEVRVNVANCPDLTKAPFRLSLAGLSGQNVVCDVGSMKYLLPVADKSKKYSFDKVAELSKVIQGQLLGAGAGPFFTHNKNCEMAANVNFSD-SKVISNSTLHGVYDETT--NKPEVIRAT--DNNFALLAHLLSTEGLQGSV------------------------------------------------------------------------------------------------------------------------------------------------- -> --------------------------------------------WGLAAQGLSGSPRIMDIGGVPYLIPTVQRDKLYDMKDYPALADLKEGLVIGAAAGPWPFINRNAEMMPNLFVNE-DKSVVQQTHITRTHDADGSYETLKLPET--ETRNAVLGNLFICEGKPGPVLKVHCKGRTGEKNFVSCMRETLQSHYGDKELVLLCFF------------------------------------------------------------------------------------------------------------ -> ----LALYTPELKDIVDDIQKGLETNYKNVEVKVLDCPDLNTEFLQLADSGICGSTRIADVGGLPYLYNKSFRDKDWEVHNIIETCGMKQDFVFGSANADINISATGGEIVVNEKVGVNAEKKDNNDDDSKND-KSDRPKVDTY----VSSSLGCKANLFICDGKNEAVLYIKASVKTGELNITNCIREALSKVKGATQIGMGGIMKVNAGKVKAYIMP-EYVDIDYKDNDAIAKSRKTVEIGPNLLMFTNFITADPKYHFSLESTICQGDVHDAGVFIESATNDTIEYEGYFTLAKYIYRVEDAYHN------ -> ---NAALFIPPLEELVSLFQAALAKNFAEVEVKVAEVPDLTQAPWHLAGKGLCGHCRLLDIGGEYNLFYAKNHHATFDFDECAKLAELPNAFMIGPGAGLKRIVGINCELMANVNVGE----RNYSSYISRLTEDEK--PLQ-LLYP--EKELGILCNLLASAGEPGKAVYFRAAKRTGAANVVSCIRE----------------------------------------------------------------------------------------------------------------------------- -> --KTYELEVPDLSELCSVMKESLQGHFNDLMVNVVECPNLRRHPYNFAASGLCGGQEVIEFGNYRHLYNLTKSPKSWNLQNLIQKYYEGDSFIIGESMLC---GPPNKECIVNATYTQWGYTFNDKSYCTFLNEEE-QIVSELVANSRSRPKTYLYGSVFVCSGERKPVLEIVAKGSFNSMNILNLMEDALHTRYFSAKVGLSGVLLINSGMIEAAVMLRTFTQTPLTEFSTINELKTTYNVSAPVTIYNTMFNFDRILD-EK-------ESLMGGRYVRNITP-YIEYKGYFTVVKKLHRVDAE--------- -> ------------------LHSGLLNSFDEVSVEVTECPNLKSQPYLLAAEGLCGSPRAIDIGGVPYLIPSPCMEKIYDLSKAPSWAEVDTSLMVGAGAGPSHVVGKLSEMIVNISFDS-SSQATNQSRICKIDDESGKHVVQRV---ENSMDCCHLTNLFVSEGKRGKVIEVRASRRRT--------------------------------------------------------------------------------------------------------------------------------------- -> -----------------------------------------------------------------------------------QASRLVQGMIIGGGLGPFQTYNRPCEVAADITFTT-RGLESNHSLVGFGDVESESSKFCRA--T--NSYIASMGQFFVTEAKPGKVIQIEAKDRRGGQNIFDMIQRALYEEYNELPMGVGGVFCLQNSSAKVSLLN-EVPSETYHTFPCVRKYKTSFSIEGPIIGAGTIVSHDPTTGYMMKSFYCWNARTLMGQFEEDDDPANACFQIYLTVATQIYRHDKP--------- -> -----------------------------------------------------------------------------------QASKQIQGMIVGGGLGPFQTYNRPCEVAADITFTS-RGLESNNSLVGFADKEEEEPEFRSA--S--NSYIATMGQFFVTEAKPGRVIQIEAKGRNGGQNIFDMIQSALYEKYKELPMGVGGVFFLNDSSAQVSLLN-AIPAETYHTYPCVRRYKTPFSIDGPIVGAGTIISHDPTAGYMMKSFYCWNARTLMGQFEQDNNPVNAHYQIYLTVATQIYRHDRP--------- -> ----------SLDEICKALQKGLSNNFKEVTVSVVDCPNLKD--WDCPAEGMSGNQKITDVGGEPYMHDKKYIGAEFNFKEVAKLIGSEQSYAFGAGSGAMSCLGHCGELIINDNFISN----DSKSVVAMVGKN-KECIAKDY--S--ASKHGGLGNIFYTDGKKGKVIKILIKGRSGEGSLTQAMRAALLENLDNDHLGLAGVFRVLKGKIKSHVQP-DYEDIDPKQMKCVKDFLQF--------------------------------------------------------------------------- -> -------------------------------------------------------------------------------------------AGLGPFAASKCSVGCNAEGICNYSLSR-----GNKSRYAKIADSN-DAKLLSCFRDLESKICGPLGNFFVTDGRNGKVIKIVAKSRVSGFSISQAIRKAFCVALGSTPIGFGGVILVRNGKVKGHVMQ-DFVDYEFRSQKTVDDWLRFFPMGDQLIMHSVLVCNETKEEWRVEHTHFYGIENEGGHYHGDISEGDIEYECYFAPASKLVRMNQT--------- -> ----IDLFIPDKIKLATVVKNELSTSFGEVTAEWVDCPDLTQEPFNLAAPGLGGDATLLDIGGTANIFPFRQ-LKIYDFKNILNQLNRSQNFIIGGGLSTQPMTLNYGHLIMNGTVANEIIAVSNKSRFAFRNRFEEQFALEILNNP--FSKCHMYGNFFVSQGLREQVLKVEAKERT-GHDFIEAIQRGISRIFPSKL------------------------------------------------------------------------------------------------------------------- -> -----------LNELISTLSEGLAATFEEVEVVEVTCPNLSLSPWNLASNGITGDVTLADIGGPDNIHYTENNGTVFNLQEISKIIKKEGYFVAGPGAASTSICGINGELVANLNLSN----RNYKSHCTLIDNNN-SYITKEY--K--SEEIGVLANLFLCKGEQDKVIKIKCKKRIGKDNFVTSI------------------------------------------------------------------------------------------------------------------------------- -> --EEKSLHVPELDEIVQVLQSALSRNFQEVTVEIVDCPNLTAEPYSLVCEGLNGSLTLMELGGFATLLPLEDKGKVYDIVETSRKIMKGKDAIIGTGAGPVSLEKSNCEIILNMNIPL-KGNLENKSIAIRINEDD-EISLDPI-ND--QQIFSYLVNIFLCEGKSGKV------------------------------------------------------------------------------------------------------------------------------------------------- -> --------------------------------------------------------------------------------QICETVSLPGGFVIGAAATKCSASKDNSELIPCVCIGK-----NNLSKEAYVDKKTDTPVLADY--N--STEISSLANLMISSGTTDVVLKIQAKVRTGELNFVTCLRKTLAEHFPDKQIGIGGAFVISKGNIKSHIMP-SFP--PRDAFGEPEIWLKYYSVSAPLTALSVFVSNDKHNDLRLEHTHFWTHD------------------------------------------ -> ----------------------------------------------------------------------------------------------------------NGELMSSNCVTK-----RNTTHFSLVNSK-GSCHCAIY--P--WMEQGPLSNMFVSDGKNTDVVHIEVETRIGNDNLISCIRKGLTEHFQKKQLGLGGVFFLEKGKVQAHVMS-DFASTLIDGPEVINDWLRYYQVGPNLVFLTTMITGDPDMHLRLEHTHFFSKPITGGHYHHDTTPA----------------------------- -> -------------------------------VSVSKCPDLTQPPFSLAAIGLSGHVALADVGGQLNMHYKANHNKHFDIKNISQEI-NGLPFFIGAGATKPSVSRDNSELMPNLNISSN----VYLSKEAYVGQDGSG-HLVDY--P--STEFSGLANFFVSEGKPGTVLKIEACGRTGMQNIVTCMRQAILDHYGENQIGLGGVLLVKKGK------------------------------------------------------------------------------------------------------ -> -----------------------------------------------------------------------------------------------------------------------------RSKVGIVEGDHDQRGIKSID--YEGHEVSSLCQLFVSSGEVCPAIRVHLRGRKEAGDLLAEMQEGLARAFA-EPISLGGVFTMPNGTAKCHVMS-DFTPEPICSQQYIEKWLRYFY-EEKMTFVAVCTSKDFALDMRMLHAHGVTDGRWCGHYHHDTTPETVEYEGFFLPAVKYVRVDQCSHTPDFAKD -> ---------------------------------------------------------------------------------------------------------------------------GTETKKAKKKKTGATSKTAAL-SSYDSCEMGFLANLMASEGQQGPVVKVTAARRKSETSLTRCIRKAMAEHAGESKVGMGGVFKVKAGQVRTHVMA-DTGGRIFTEASQVQEYLDLFTMGPGLVAASVFLSKQPETKARLEHTHLFSEMKTGGHYHGDVTPAEVEYEGYFALCRELVMIDK---------- -> ----------------------MAKEFREVKVDIAACPCLTRQPYNLAGVGINGNSSLMEIGGPENVVSHNDYGLTWKVQELLSSA-YFDSFIFGNGYAAKPYMLYNGHLIVNAMYRA-PSNFTNASRIVFADASNRQRRIEMLTDP-DQMLCSYMGSFFISDGRPGLVLRVRAKGQTSIFDIITIMQNSLYEHFGNK-------------------------------------------------------------------------------------------------------------------- -> ------------------------------------------------------------------------------------------------------------------------------SQLATVRRDEDRPSLSSY----NSSTMGFLANVMACRGYQGDVVEVRASVRKSSESLTERIRLGVARAYDAPDKGLGGVFKVTKGKVKVHVMA-DTAGRVFTHSSQVQDYLKMFTMGPALTCATVMTTRQPAGKVRLEHTHLFNAGTEGGHYHGDVTPQDIDYVAYLVPCEALLLVDK---------- -> ----LELYTPELKDIINDIQKGLETNYKNVEVKLLDCPDLNTEFLNLAATGICGSTRIADVGGLPYLYNKAFREKDWEIHNIIETCGMKQEFVFGSANADINMSDTGGEVIINEKVGVKKKEIEASMDENKENNKKSETPQVKV---YYSSSVGNKANLFLCDGKNGPVIYIKVSVRTGGLNITNAIRESLKKVKGAKQIGMGGIMRVNNGKVNAYIMP-EYVDIDYKDNDAISKSRKTVEIGPNLLMFTNFITDDPKYHFALESTICQGMEEH---------------------------------------- -> --DTVPLAKISQNQLMESLAQALTPSFEEVQVDIVETN---FDAFGWVKPGFGNICHLVDVGKLENLNVAEFRKEQFEFNDIIENYTKIPQFFVGAAAANFFAYNKNGELVLNCDDVT----CSSLESLVSSDGQ-----QTIVPNG--YRSTGFIGNLVASDGTPSNMTRILARNRLTGSDFGQILTDALSP---FKDLAFGGIINLVQGSFTFHAMP-DTFPAGNMTDPEIQQWLHFFTENTDYTCASRFVADPSLLDAASAHVHCFRDGTFVGHYRYDNSPQDVVYEAFLMPCDTL--------------- -> ------------------------------------------------------------------------------------------------GGGPLKKLGHNSEAIINFRTGEIGKAIVCHNYVASWQKDG-TRECKVV--E--KPQISYIGDFYASQGLPGRVMQVKLKQRKSEADILALLRDLLIERFGTRSIGMGGVILQKRGKARLHILRPELGEGPL----EMSQLCTQFEATGPLVGLCMLMTNDCGIKMNQTHMHMFNNEGTGGHYEEEVSADSVEYEAYFSFGTRAVHFDAPK-------- -> --KQHSLFVPTLDDLSIGIKNSLEKNYKNVEVCVQSCPDLTY--LGVASTGICGRTCLLDIGGVPFLLDPEWQDVYFDLKKLLEAIERPMGNIIGAAASWKGRVGVNGELMASSCSIT----QRNTTHFSLVDNKG-SCHCAIY--P--WMEQGPLSNLFVSDGKNRDIIFVEVETRIGNDNLISCIRKGLLEYFEEKQIGIGGIFFL---------------------------------------------------------------------------------------------------------- -> -IEKASLYVPELDQLAAMLKESLRGNFETVETKVVECPDLTK--WGLAAPGICGNQRIIDIGGVPNLLPKYHGTAFFSIPQIAEDVGMKGGYVYGAGAASSKVVGVNAELMPSEHISEK----CRCSRYSKVLEDG-SHTMEKY--N--SNEFGLLANLIACDGKKGNA------------------------------------------------------------------------------------------------------------------------------------------------- -> ----------------------------------------------------------------------------------------------------------------------------NRSLIGFYSKECGSPTSERA--S--NTLLSSVGQIFITEAMPGKVIEIVAHKRIGGPSIFDLIQASLYDKFSDLPMALGCVFYLQNSGVQASVLC-ELPQEPYHTFPCLKKYQASFTIDGPIIGVGTVLSHDPKKGFSMSTFNCWNARLLTGQFENDVCPEKATYTVYLTPAKKLYRQDKPV-------- -> ---------------------------------------------------------------------------------------------------------------------------------------------------YPSEEVGAASNLFICDGNDEPVLYIKVSVRKGKLNIINTIREALKSVKGAAQIGVGGIIKVTKGKVKAYIAP-EFVELDYNDTDTLEKSRKYFEFGPNLIMFTTFLTDDPKLHLTLEATTCYTNSNEGGVYVESTDDDNIQYEGYFNLAKYIYRVEDA--------- -> ----------------------------------------------------------------------------FELRKILNVVGMPKGTALGAAAAWNGRIGVNGELMPYASVNN----GTNTSHFSIVDRDG-NCECNHYPYL----EQGPLSNMFLCDGIQGDVIKVEVEVRTGEENLVSCIRKGLIETFNGRQIGIGGVFIVKKGKVKMHVMP-DFYPSMVDGSEQVKEWLKYYEVGPN--------------------------------------------------------------------- -> -----------------------------------DVPDLTQ--YGWVTEGLGKSPVLLDIGSGEYLLTASCHNSTYNITSTTQSIPELNGSFYGASALYEPVIGHNGEAVNNYKFGV-----GSSSIGAIVSDDGSSIDVVQLPT----DSIGPFGSLYFTQGESVDAIHVHVKTLLASERFDYAMQRALTDAKDLGAVGLAGVIRLLQGEITFHVMK-DFVDYDLTS-ADWSWWDTFYPMRSTIECSTRLLSNDTMFTSIGAHTHCYKDYSVVGHYENDTLPPAHEFEAWLVPSPLLVRVAKPSNGN----- -> ---------------------------------------------------------------------------DWEIHNIIETCGMKQEFVFGSANADVDISATGGEVIVNEKVGVKE---------------------------QVSSSVGCRANLFLCDGKNEPVIYIKASVRTGQLSVTNCIREALKKIKGATQIGMGGILRVNAGKVKAYIMP-EYVNIDYKDNDAIAKSRKTVEIGPNLIMYSNFLTDDPKYHFTLESTICQGMQHDAGVFVEASTNDTIEYEGYFTLAKYVYRIEDAYHN------ -> ---SANLFVPTLEAAKDALASALKEDYKTSSVEIVDCPDLKE--WKLCQSGLGGQSVITDIGGEPFNHPKYNQKVRFSMPKVAEACECSACPALGAGACFAGAIGHWGELTVSADFSK----GKHNCIAATVDQETRKCVASKY--D--SEMHGGLMNLHFTDGTPGKVLRVRAKGRVGERSLSQTLRRGLS-------------------------------------------------------------------------------------------------------------------------- -> --RTVPLFVPPLEEARDALRTALAEDYRESSVDIVDCPDLRE--WRLAQAGLGGKGTLVDVGGEPFNHDKLNSKVKFDMKKVCSSFGRDKAAILGAGACSAEINGHLGELTVTANLSD----GANNSVSARVLEDK-SCCAEEY--K--SLFHGGLMNLHVTDGSDGKVLRVRAKARVGEQQ------------------------------------------------------------------------------------------------------------------------------------ -> -----------------------------------------------------------------------------------------------------------------------------------EDKKSETPQVKVY----YSSSVGNKANLFLCDGKNGPVIYIKVSVRTGGLNITNAIREALKKVKGAKQIGMGGIMRVNNGKVNAYIMP-EYVDIDYKDNDAISKSRKTVEIGPNLLMFTNFVTDDPKYHFALESTICQGMQHDAGVFIETSTNDTIEYEGYFTLAKYIYRIEDAYHN------ -> ---------------AAVLREDLPTVFKECTVDILEAKSVVSSWTNLSIRGLGGSPKLVDIGGVPNLLEPKGHHLSFDICSVAETCGLSQGLFFGAGAGDARHVGRNSELMPLYLVSEEGTVSHNETRVAFLTPEKGDDCFECTKYS--STRVGFLANLFACKGEPCSLLSVKVSGRTGSQDFISAIHRILK-------------------------------------------------------------------------------------------------------------------------- -> ------FTEYSLDKISEALQAGLSKNYKFSEVSVVDCPNLRD--WDCPSEGMSGNQKIIDVGGEPYMHDPNFIGAEFDYEQIAKMIGSEKSYALGAGSGAMSCLGHCGELIINENLITN----ESKSIIARVGKEK-ECIAEKY--S--ARKHGGLGNIYYTDGKQGKVIKLKIKVRI---------------------------------------------------------------------------------------------------------------------------------------- -> -------------------------------------------------------VSLYDCGSPKQVEMVEGRTAHVCMDKLMAEREAGNTWLVGAGATG--AGPCNGELIVVASLGSDRDTTRAGIRSVAVYADPLACPVSTR--PYRSLCVGPVANMVAGPPLRAATTCVRLQGRGIKTNLISVLNDVLRRGFARGQVAWAAVTRVTSGSVKAHVMP-PFPDHDLSTPALVNDWLQFYEMPAPLTMYTAAITDDRHEGLRLEHTHFTSDTGAGGHFHHTTTPEHFAYDVVIIFATRLFK------------- -> ----------------------------------------------------------------------------WSVSEIIRDLGLGRVQAFGPGAPGYSNVQQNAELVCKMELCS--GGWECRSKVGIVEGDQDQRGIKAIDYD--GHEVSSLCQLFVSDGEVCPVIRVHLKGRKEKGDLLAEMQEGLARAFP-QPVSLGGVFTMPNGTAKCHVMS-DFTRGPICSQQYIDKWLRYFY-EEKMSFVAVCTSKDFEGDMRMLH------------------------------------------------- -> -----------------------------------------------------------------------------------------------------------------------------------------GVSCKKY---ESADQFGCKANLFICQGNDGEVLYIKVKTRTGKESLIQCLRNALKKVKGDSQIGVGGIVKV-KGKVKAYISP-KWVEIDYNDKDAINKSREEIEIGPDLLLFTNFLTDDPNYHATMESTICQQSPHEGGVFIESAQDDIIEYEGYFILSKYWFRIEDPYHNIDIEN- -> --------------------------------------------------------------------------------------------------------------------------------------DKDIFKIQHY--P--SNEIGCQGNVFLSEGKDTRLLLIECETRIGDDNFCSAIQKVLQKYVNTR-EGLGGLIQVLNGDINGYLISNN------NEHKK------VNANGSNIIMYSTIISNDVKNKLNTNNCQFINKKNQAGNYVNDTTPKTIKYRGYFNIAKYLYVVGNPNQS------ -> -----------------------------------------------------GKSVITDIGGEPFNHPKYNQKVRFCMPEVAEACGCGGSPALGAGACCAEAIGHWGELTVSAHFGE----GTNASVAATVDHETRKCIASKY--D--SNLHGGIMNLHFTDGTPGKVLRVRAKGRVGDRSLSQTLRRGLSTFP--NAVGLGGAFKVLSGKVKAHSQP-DLCLCPYYNKEEMKPFLQFYEG------------------------------------------------------------------------ -> --------------------------------------------------------KLVEGGGEPFNHDTYNREVAFQLERMARLAGHQAGFLFGAAAGVKQLGGHIGELIPCLVLQG-----ENKTKAVRVDSETRSSIVSA--D--TSGLCGGISNLYLSQGKAGKVLKVVVSGRTGPISLTQSIRAGLRNIPEHCQVGMGGVFRMKSGLVKAHVNP-DFEVL----------------------------------------------------------------------------------------- -> --TRFPLSVPQGQALSRAIENGLKQVYKQVKVRLVPTNDLSAQPWNLAASNLGTNGIFCQLGGAKYVEYKQGHSVRFDMSSVLDQLHIKNNLVIGPGAGDLTHLSVNGELIFNMTFDQY-NKVQVQRSYSSIVTDDNQAYQAEYQ----PKTCGPFQHVMISSVKSSILIEIDVQQRL---------------------------------------------------------------------------------------------------------------------------------------- -> -------------------------LYDTFSVSVVDSPK------DLPGIGWLSDGMLLDVGGVPNMDNVERHDVQFDLDDLVENT--SSAFASGALAAAPCVAGCNAEGIMCCELVAGERKSRSASKYTKITSER-PWSDA-----TPLRKLGCLGNFFLQKMHRSSVLKVHARRRLKGHSFTQWLRDAFVEV-GQRLLGFGGVVFVKSGFVQGHVMP-DFLPHKSENATMCNDWLRFFNGPGNCVMFTTMVSKEVELHLRPEHTHFFGVENQGGHYHGDVD------------------------------- \ No newline at end of file diff --git a/esm/examples/5ahw_1_A.a3m b/esm/examples/5ahw_1_A.a3m deleted file mode 100644 index dbecfbb..0000000 --- a/esm/examples/5ahw_1_A.a3m +++ /dev/null @@ -1,2048 +0,0 @@ -> -SAYQTVVVGTDGSDSSLRAVDRAGQIAAASNAKLIIATAYFPAPIYAILREANDRAKAAGATDIEERPVVGAPVDALVELADEVKADLLVVGNVGLSTIAGRLLGSVPANVARRSKTDVLIVHTS -> -PSYRSIIVGIDGTPRSLRTVETAARLARDAHATLTVTCAYPELAVDELLKDAAAHVDDQGSEPAVQYAVRGGPAEALLSIANHVSADLIVVGSGDFASPFGRFLRAFPAEIARRAHSDVLIIKSA -> -TAYHTILVDTDGSDRSYRVIDHAAELARASHARLLILCARHDIPTDTILRTARHHATAHGATDITTHILAPPTLHALLHLAATTGTDLIVTGHPHRHPLLARWLPSLPIELARHAHCDILIVHAP -> -FSYSSIAVGTDGSATSMAAVRAAASLARVYDASLTIICAHYSAGAQEILQRAREIAEAEQAKDIRTVSRGGQPAAVLIESVSEYDVDLLVVGNKGMRSLAGRVFGNVPGSVAKKAPVDVMLVDTQ -> -ASYQSIAVGTDGTDTAEVAVRKAAGLARDTGAKLIIVSAWHGQNAQEYVESAAKIAEEEKAPDVETFTVRNPAANALVDVVKERGVELIVIGSQGVHSLAGRVFGSVAMEVLKRSDVDVMVVNTE -> --QFNRIVVGYDDTEGSKNALNLAIRLVKENDAQLLVAQVFEEKSVDKAFYNAREAIEPYNI-NAKYDVLEGSPADSICDYAAVEDADLVIVGNSGKGGIKRMFLGSTSAKIAQNAPCPVLIAKDK -> --MFTSLLVPVDGSAHALKALSIAAQLASPEA-TLHLLYVLPHLEIEAVLQKAQTHLRSRFDGRIETHGRHGDPARIIAYEAEKLGAQVIVIGSRGLSDLSGMIMGSVSHKVSHIATCMVISVHDD -> --FPTHVLVADDGSPESDRAVDTAAQLVRATGSSLSLVHVS---QGRVLVGRRVAELSAGGIEPEHAEVRLGRIEAAVTDTAMEWGAGLLVVGARGGNPGQRYILGDVSVHLVREARCSVLVVHTE -> --AGSVIIVGTDFSADAERALRYGFKLARALGGLVELVHVTPELEVEAAREALETLVTETDV-PAQAHVCIGDTCQALLDRADEVGAELIVVGRQGAGALGRFLLGSLTDKLVRRSERAVVVIPPG -> --GYKNIVVGVDTSPQAYEVFKKAMDVAKTEGSTLHIVSAVPFIERRAILETYVAEAKEYGVETVTLTIESDHSKNLILTELEDFEGALIVIGASTKTPLKRFMIGSTAKYLATHAPCNILIVKSY -> --ALRSIAVGMDGSPSSERAFEWALDLAKLGGASLTIVGAIPLHTMSELLRRRAESARQAGVHPVASILLEGAAVDELLNFLDEHRPDLMVLGARGVSGARRVLLGSVSEGVLHHAHCSILIVRPP -> --GYDTVVVGYDGSPDADRALEAAADQVGPS-GTVHVVTASHPEPENARQQVALLRLQGRGV-DCEGHVVVDDPATAIIDVAEREGADLVIVGSRGLGDVRRFLRGSVSARVAVHAPTSVLIVHGT -> --MYTCIVAGFDGSDAAKKAVEKAAMLAEKLGAKLVIVTVVPTPAVREGLDKLAEDIGRYNV-EIETMVVEGDPAESLLDVAKGKGCSAIVVGRRGR-GLAVKLLGSVTSKLVNIAKGIDVIVVEP -> ---MKKILVGTDTSASADMAVEAAAEIARLADAELLVLHVRPASDPDGYLATMTKR--FPSL-RVRSWSEPGEPAERLLEVAEAERVDTIVVGNKGVRGSRWRVRDSVPTMVVRHAPCSVFIVDTR -> -NNYRTIVVGTDGSALAGPTVARAALAARREDADLVIVCAFAEMAASTAIAEAVAIAQEYGATIGAALLVDGDPAAVLVNVATEREAQLIVVGARHHRSLAERLLGTVATEVTKRAPCDVLVVRP- -> -VPVSRLLLATDCSPAAGAAEAAFLELLRHCDSALVVVGGWVD-TIEDHV---SALAERAGEVFDAELLGRGRPSAEIARVAQEHDVDLVILGRCGHNVLAERLLGSTAEAVCQQARCLTLVVPG- -> -MIEGPIIAATDFSKAAEQAVAQAARLAAQRGVKLVLAHVIPPLAAEREMQRL--RQIESALTEVETVIAEGEPTRELAALCQSQNAALLVVGAAGAGNIVEAVFGSVARKMVRRAPCSVLVVRP- -> ---MHKILIPVDGSVHSMKALKIAADLAAKYQGRLCILHVLLRGIGEIILDHFAEKARTHGVEFELLPIVSGKPADEILKMQEKIEAGTIVMGARGVSHSDSSTFGSVSQEIFNRAQCTCISVK-- -> --TSRTIVTGVDSSQTALNAAEKAAELAEGLGAELHVFCAYSISQARAVADAVAAVLREPDL-TIKASAEEGTPAEVLLQQARTLKADTIVVGNKHVQGFS-RILGSVARKVAAEASCDLYIVNTT -> --ADKTIVAGVDGSETAAIAAERAAVLAQALDARLHLISAFGKFNETEVAAKAATLLRSPDV-TITTAAAEGKPGEALVSVAEALGADLIVVGNKRVQGIAGRVLGSIARDVAAHASCDVYVAHTH -> --MSEIVIVGAVDTETANMAVDRAAHVAAALGAKLVVVTAYGDDTAEVFAEQTAARLQAS-I-ECVAVAQRGKPDDVILDAAKRFEATLIVVGNVRMQG-AARLFGSVGNDVTHHAPCDVLVVKTS -> ---MKTIVLAYDESPEAGRALEKTVELAKVLSATVVVTSVAPVMPPGRLAHDAVAILTEQGI-VAKAVTALGEPGHTIVELADQEKAEMIVLGMSHHPH-LSRIFGSVSEDVAHHAHCDVLLVH-- -> ----MALVVGYDRHPAGRAALVFAGELAGALNVPLHVVHVVNGR----ERQRVADALGAADL-QWTYHQIRGDPAEVLVQVADEHSASMLVVGRPQHGPEGHVVTGSVARNVLRHSRRPVVVVPEY -> --VFNNIVVAYDGSDHAVDAVMKARDFALADPEVIHVVFVTTHPESEKVKAGLGVAIEGVEDQVTIDVIPGYTPADDIIEFAKEIEADLIVMGSRGLGAIRG-VIGSVSYAVLRESTIPILVIK-- -> --PIRDIVVGYDGSDASARACSIAVRIAGLLGARIHLVHAGELR---AA-MELVRSYSERVGVPLRVISREGSPATAILAVQEETGADLILVGTRGLHAAPRLFLGSVSADVLARSRVPVTIVP-- -> --AVKRIVAGVDGSDAGKLALEWTARLAKTLHS-EVVAAIDVP-KWCRPLKSVGV--------RYRAIIEDGRPASVILNVAERERAELIVVGRRGHGEVAELLLGSVSHEVVLHSKRPVLLVP-- -> ---MRRQLIALDGKDESYYALEWYLNNVCRSGDEAVIFSQFTLNKAEEITTKASEKIKTKGIKCYVIIKSGLKPEEAILQAVTEENVTHVIMGTRGLGTLQRAFVGSVSSTVVSNAKVPVTIVK-- -> --GASQYMVCLDGSEVSKNSLRLALRLLRPDDDSLLLLWGYDI-QSESYLAEAEKLARESGAKQVTTKAVLGFPRDQILLVAEEEGVEMIVMGARGLSPIKKLLMGSVSSHVLSNAACPVLVVK-- -> --AIKTILWATDGSESAQKAGAMVKQLKEGFPQAKVVAVQ-DQPQVFSLF-ERTP--------DIEFMVAEGQPSAQINKIAEKIHADLIVIGSHGYTAWDRFVLGSASRHLLDHTTYPVLVVR-- -> ----MKFLVAYDSSATAKHALERTLGLLHRDRDSLPELLLTEDT--IRVM-------KSLS--------DLLTAEHEILDQAAACEADMIVMGSRGMGTIQG-V----SQRCLNEAKVPVMVVR-- -> --KYKNILVPYDGSKHSQKALGMAVDIGSMFGSTLYVVNVADLSTSELQLKKIHEKYRDSGV-SMKEFVLEGNTVDKLLKFAQDKEIDFIIIGSRAYLESQK------------------------ -> --MTLRILAAVDQSIHAEHALRFAARMARGLNASLAVLLVLPP-KVRRILD---EEGVDAQLLIRKYVPTAASPASVIVEEAEKRGFNVIVVGAKGVTGREDVSIGSSALWVAAFAPATVVIVR-- -> --MITSIVVGVDGSKSAGRALLMACEMANQFGAALHISHTPRDEAAEKLIDGARKVALDAGVEQVEVNVGQGDPARDLTEMAQAVNADLIITGRRGLGDLGAFVLGSTSHQISKQAKCACMTVP-- -> ---MKHLMVATDGSASADRAVDEAARMAKQSGADLLIVHVIGGYYSAQVLTQAKARAQALGVPDARLASYRGEIVPAILQAAQQQHIDAIVVGRRGTGHMSSLLLGSTAQKLVSLSPCVVTVVP-- -> --MFRTIVVGVDGSECSARSLDLACELAKLHGGEIHLVHSPELVAGKKVMEQATAAASAKGITPATTTIGEDGPVDDILTIVQLYGADLIVTGRRGLSSVGGLFLGSTSQKLAQSADCPCLTVK-- -> --MFDVIVWATDGSANADLALDYVRKLAEGGQSRVVVVHVKEVI--QKIYAQVNDLKRGVDASLRAHHAAAGHAAHITADIAREEGADLIVVGTRGLGPITGLLLGSVTQRLLQVAPCPVLAVP-- -> --MFESIVVAVDGSDAATRGVEAACKLSEAFGGEVHLIHALENKLTSDVMDAAVKQVRSAGITPSSATVAEGDAFDEIMMIVGLYAADLVITGRRGLGTLSGMFAGSTSQQIAKHASCAFLSIK-- -> --MFKKILVPTDGSEQANKALKVACEMAIAIDGQLNILSVFKHHYSKELVAEAKELAISFGVKNVKGFVRIGPTTKEILEFVKDKDIEIVIIGKQGKGDLSGYLLGGVSHKVAGLSDIPVLVV--- -> --YFKNILVALDGSDHAMKALELAAQLEDKFDSSLHILSVYRHYIAREIVEMGCSRAKELGATGIKGVVKRGKPSRVILDYVKEHPVDCIIMGKRGIGDGGGGLLGSVSNRVATLAPCTCITV--- -> --STPPIVVPYDFSTDSREAVDKAIALLGS-GEGIYVIHVLGELHATQAIR--KELADEKYS-DVKINIAFGDPGEQICHFAEKQGASAIIISSHGRSSIMRVLLGSVADRVVRLADRPVIVLK-- -> --MIKKILVAYDGEQ-SHSAFLFGLDMAKKFDAEIEILSIVRILHYEKFFKLLRHEARSHGL-RIKTEIALGHPAEQIIHWAEKKKVDVIILGPQTKNTLGQWLLGSIPDRVVHHAPCTVIVVK-- -> --MFGKVLLAYDGSQTADLAFTRALQVAQEAHAPLHVVAVAWSPQCWEYLNLLRSKATAAQV-VLELEVVEGNCSDQIVAAADRLEADLIVIGHRQRTLMQRLSEASLAKRVVDHAHCSVLIAR-- -> -NQFNRIVVGYDDTEGSNKALQLAVQMAKGNPAHVLVANVYDEKPTHAIISNSVKAKQELEPHIQKYDSLDGSPAESICDYASAEGADLIIVGNSGKGGLKRMFLGSVSSNIAKQAPCPVLIAK-- -> -TSIDRIILAVDGSAPAIEATKYAIGLAKR-NSEIIAIFVDPDGYGLAGLKLAHKYGKAYCINVK-LLLLSGNPVKQIINVAEKEGADLIITGDTGLTGIKRIALGSIAEAVVEASDVPVLVVK-- -> -MRFKNILVPYDGSEHADRALDVAGDFLRSNPARVHVISVTYVAVFSQEQKAAHEILPDIEPERVCDTIIRPSAVEGIEDYARRKKCDLIVMGRRGLGGLRQF-VGSVTKEVLHRVDLPVMTIK-- -> -MPFTRILVPFDTSELSVKALEKAVEISAI-DSPIFILHVISEIEMIVILEDVKNTYAKHNISIT-TEIKIGDPAEIIVDFTKQNNIDLIVMGSIGHKGISGMKLGSVARKVAEEVNCALLIVR-- -> -NLPKKILVAIDGTPISDKAAEEAVRMAAS-NGPYRSLLVLPNALRNRIFYVIQKNAGEAGVPLD-IRVAYGEPADEMLAIADHEKVDVIVIGSSGKGFIKRKVLGSVSNRVVQNAKCSVYVVR-- -> ---MYRILLATDGSKSMKRLVEEVLTIAFA-LAEVTILNVIEQTEADRIVDEAAKPFRDKGLIVKEVVDTEQSPADVICDFASKGGYNLIAIGSRGLRGMKELFLGSVSNKVAHLGCTNVLIVR-- -> --MKEKILIAIDSSDSSSKVLAYGINLAGKLD-EVKVVHVIE--AGQELMEAAKKQTAAAKVPVH--ETLVGNAAQQILTAAKKSEASMILIGSRGMNAVAEFILGSVSSKVAMYAEIPVLIVK-- -> ---MFKYLLAVDESENAARAAQYLANLAGIWQLDITVVHVVNFK----VLNEQTVAFDKFGVTIK-KQLINGHPSDKITEFAKLNDFTHIVLGSRGLTDLQGLVMGSVSHRVLHQAHCPVTLVK-- -> -AMLKQILVGYDDSPAAQRALEFALKLAQG-FCQLQ-AAVLPAGLRPGLSQKVLERAAQAGVKAA-WKVVPGSAGDVLLAEVRSGSFDHLVIGNSGRGTLARWLLGSVMNEVVEHSQIPVTVVP-- -> ---MRKILVAYDGSDLSKKALNKAKAQIKFEPTELHVVTIVPNTDFKEELKAIREN-MNIRTSVI--DNYHWNAGMKLCQYAEEHNIDEIIVGSRGLGGMKKFFLGSVSNHILHHADCEILIVK-- -> -MLYSKILIPYNNTDLSNKALETVKNFAKVNPAEIDLLFANQVPYADETLQNAVNYLADLK-NPIHKYIVDSQPITAILNHVETNKNDLIIMGNRGLRGIKEF-LESVSHVVVQKSPVPVLLVK-- -> --MIPTIMVAIDQDDASKAALLWAIELASILSAKVVGVHAC--G-----MDSIRKPLSDSG--LDELVLRDGNPVSVLLMLESEVGADLIVVGSRGHSVIGGL-IDSTSHHVSEAARCPVVIVH-- -> -TEIKKILLGIDGSDGSYKAAGYAADLAARVGTVTLMFVVSD-----SRFNRAKAIMEEKHVTYD--MVEMGNPAQKLIATA-ESGYDMIVLGTRGLSAVKEFMLGSVSSKVVQHSKIPVLIVP-- -> -MVMERLLVCVDGSKYSEEAVRYAVEIWRK-YSSITLIFVWHPPYEIAKLTEAEKILKDAGITYT-VIKKIGNPAMHIIDE-SKKGYDLVVMGSRGLGSVEGFLLGSVTSRVTHHVRVPILIVP-- -> --------------------MDHAGFMLS-GTCHITILHTMRHLRIAPFMEKAREMLFEAGLTEERVVDGSRSPADDILKEARSKGYGTIVLGRRGLSGVKAFVFGSVTRKILHHSAGLSWIVQ-- -> ---MKKVVVCWDGSDGAKRALKAGQRLVDENI-EMVVSEVFEP-KAQKAHDEFENLA--DEA-PK--NKEAHSAREAICEEEKLGNVDLVVMGTRGLGIVSRLVLGSVSEYVVQNAHCPVMIVR-- -> --MKSKVLIPVDTARNSLTAEEYALKLNWRMP-SVTLLNVVNTKVLKKAAEP----FSKAEV-D---RVVEGAPGLTICGLAQDENFDMVIIAQSGLSEWEEILGGSVVRTVLNKCQIPVLLVK-- -> --VPKKIVVAFDTSLHSIHALKAAISISEKYRSEITVIHCVEYP---PLMKEARRR--KVKIEIVYT---TTSVAESLLLESKKIKPDMIVMGSRGLGGFKSLLLGSVSNAVVTHSTVPVLIIK-- -> --PYRKILVPCADEVSAAAAITTAAALATVFD-EVLVLHVVHPRKLAPVLER----FAAAGV-S---YLETGDPGSKICELAAAQRADLLVMTRRSLGFWDRLVGGSVTEYVLRHAPCSLLIAH-- -> --MIKRILVAYDDGRQAQKALEAAIEIAENTGAVIYITSAYIIPYLKKILQEAADNVSQKNI-PVFT--LDGSPGKMVVQFAENNQIDLISVGSHNRSAVNRFFMGSVSNYVLQHAKCLVLVAK-- -> --LFHKTLLPVNDSPQSERAVQKAIELYQAGV-DNLLFNVYDTSESLQVLEKYQKMLADHNI-P---KKAGGDPASLILDLENDGQFDLIIMGSRRLNKFQELAFGSVTDKVTRLVNIPVLVIK-- -> --KSQKIAIGFDESKYSKKAVEYVINNFE-KS-TVYLIYV--EEKTKKELIKEVEAIRKKGF-K---EYIEGYPPDKLVNEAKRKNADIIVVGSRGMGKWKGSVLGSVSQKLTVIARTPLLIIK-- -> --MFDKVMVAIDKAEITNKLLDATVEIAQNKQ-QITLVNVSQD-ASLDLLHQAKSKLKSAGI-NPETIHLKGDPAYEILNYARETGQQLVIIGSRRLMGVKGMMLGSVSHKVSQLSNCPVLIVH-- -> --KFEKILLPFDDSTYSINAAHCALSIAKQMGS-VTIINCYDLNKSENILKVAEEIFRDRGV-DYTLKPIRGLPGKILADISKSKEYDLIIMGSQGHSDISGLFLGSVTHKVLSTMYCPVLVVP-- -> --MFSEILVAINGNAQSDKVLE----LAMRVA-DATRVHVVSVIIVEKARLF----LQARHI-K---TVIAGDPEHAICNHAREQGCDLIVMGHHHMSTFERLVGNSVAYEVLQNAPCPILIEA-- -> ---MNKILLAVDGSAYDEKSVAFINDKAAKVC-NIDVYVASVLP----KLLTNTVQKLTVHG-NAS-HILEGDVAKKLLEFAEQTGVDLIVMGCRGLSNYEELVLGSVSMKVIRSSSCPVVIVK-- -> ---MKKIVLAFDGSTHALNAVNEAKKLMQGFPSSVTILEVLDIARKAVRIDEVKQQLIGLLD-TFEISILIGDPASEIIQHVKKNDYDLLIMGSRGLNLLQEFVLGSVSHKVMKYVSIPVLIVK-- -> -------PVDLKENGYSPAIAKTALALANAED-EIYLVSVLNGV----KLMAFAEQHMGVDN-R---HVLLGNASEEILKFAKAKACDLIIIANHKTNMLGNPGFGTITAKVAVQAACSVLIVK-- -> --TNYKIAVGLDGSDSSWKALEEAVKQAAAKVAELHIVSIQEASKLERVQIKAKTLAENAGV-KVFAEITTGSSTTVMVDFVKKNSMDMLIIGDTGHSSIWGALLGTNAEKIVRNARCSVLIVR-- -> --MFKKILVGNDGSEGAKKALRVAIEMAKRYGAELHSISVEEPHYFAKINGEAKEISARERV-VLHTNVLAGHEVETIVDHDRDHHFDLAVVGFMGHSKIYDRVWGSTSQNIARLVPCTVMVVK-- -> --MFHHIVHANDGSENSLTALRTAIELAAVADTGLDVLFVEDAPHIGRHKALAERIAARSGV-TLKTHVFTGHPVGHIVAFTREAKADLLVIGATEHADLWEHLFGRRSDRMTHKVDCSVLIVR-- -> --MFQRILIAYDGSPESKKALETGIALARELKADTSLVSVIEPGKLGAMQAEVKQKAAQSGM-EIDTLLVEAGEAEGVLEAVRETQAGLLVVGLRPHDHTVE--FAGTLRRIANQIHCPVLAVP-- -> ---MERQSSPHVSSEPAVKALELAIAMARQNAAALHLVCVEEPQRFRPVVERARLRAEQSDI-KLQVHLVSGHPVRMIVDLVDEIGADLLVIGATGHSALYERMIGSRADRIVQLAACPVLVVK-- -> -TVSRRILVGLDGSQNAFDAFECYMANVHRPNDYVIVAYSPNVSERAMNVRKILEQSEVRGC----VHLPNSNVGHAIVKEAEKENVELIVIGSRGHGVIRRTILGSVSGYIVHHSHIPVLVQP-- -> -TPIKHILVAVDFSPMALYTTRMAAQEAQLHDARLTLLHIFNPQLAHAEMEKLRQSVAAGGIPQVELEESGENIGKAVIAFGKAHAVDMLVVGSHGHGAIGRLLLGSVANDVVHYASCPVLVVK-- -> --MTTPVLICIDGSNLSHQAATAGLKVL-RTDAALTLLTVIPEPAQRADAEALLATQKELGIASAEHVVLMGPAGALVCEYAANVGAEAIVIGSRGHGGIRRAILGSVSDHIVRHAHCTVLVTS-- -> --MYNKILVPFDNGIRSQRALNTAIELAKKFQAKIFIFTSLNIFRSRNNIEKALQKVKKEGLNISDKDDLEDIPGESIIRYAEKEEIDLIVLGSNNLGVFDRVFLGSVSNYVIHNAHCQVLVIK-- -> -FP-NRILVNLDKSAPAQKALEMAMQIASATGSELHVVH-----AAEG----HLKELLSEGAPASNRHVRAGTTDNEVMRLAQELKAGLIVVGNRSADAISRIVLGNAADSIVRHAHCPVLVVR-- -> --MSGTMLVAVDGSPEGYNALIWVLEHIKE-EGRACALYVISPAEKEQVINRIKELAHDRNV-DIEIIVRTGDPRSEILQTAEEVGADLIAVGSTGKGLGARILLGSVSTYILTHAKVTTVVVR-- -> -TPISEILVPVDFSECSRRALQYAMRIAAASNAHIHLLNVIDDPQFLNVMSPE-----DRARFRTTTSIRFGTAYHEIETYAKEHDIELIVMGNSARSSLSSAILGSVSGHTIRHAVCPVMTVT-- -> -EEISKIMVGIDGSEASIKAVRKVLDMAKKYSAEVIAIHISLIPQMKIWLKNIMIEANEKNIFKALVKETTSSIVNEIIRSADAENIDLIVLGSTGKSRLDRMLVGSVAQGVMTNAKCSVLVVR-- -> -MELKKLLYAVDLEDAPHPAIEHVKMVASLTGASVSIVYVLPSEPTQALLEKMEHTNFPEG--VDDCAFLMGKISEEVVKYAHKSDIDCIVVGAHGRIGFRQLFAGSVATEVVKKAHCSVSVIR-- -> -TEKNNILVAVDGSKAAYEAFLEALKYKETAK--ITLLSVIDQALAENYL--NQLAENAHTKHHIEKVVLEGNANKCIVQYATEHVIDLIILGKTEKNLIERVVLGQTATYVTKHAPCDVLVK--- -> -EQYKNVLVAVDGSDQAYHAVQEAIEIVKRNDGKLWVLTVKETNMGSDILAK-VKELVNGQVELDATDLYDNNAKRKIVQYAADNGIDLIVIGSTGTGMIDKLFIGSTTQYVVNHAPCNVMVIK-- -> ----MNILVPMDLSSHAQLALKEATKLFKGAN--FIILIVVDIII--NAFIERQKEMFPNVIIE--FDVCSGEAKHQIIHYAKQHEIDCVVMGATSKRALSKVILGSTTDYVVKHINHNILVVR-- -> --MTKKILVAIDGSENSFDGLYEAIDMAPKTHADLNLISVVNDADAEFNLRKAESIVDNSGL-KCKIRVLYGEPQDEIIDYASKHKVSLIIMGKCRARGVERILTHSVGNFVVNHTKINTLIVN-- -> -MP-KHILVGYDGSETARRAYLLALDLAACAGAAVHVVSVMQWEDRLNGLREEVEALQPDPGVPVEVALVHGSPGDALLSYVAQHGVDHIVIGHTERGALARWLVGSTSTDVLAKAHVPVTVVR-- -> -NFYQNIMLPVDGSQESIDAFKRGIQQAKLWGSHIFLVHVLPEDSFLSALENY---ANSQG-VHIHKELIYGEPRTQITKLVERWAIDLIIMGATGKGRIAKVLLGSVTSYVIRHAKCDVIISR-- -> -MLFKNILLAFDGSTASSKAAEYAIYLCKLEGSPLTFLHVLDHIDAEKWIKPIQERATTEGI-KSTIAILDDNKVETIVQFIQKDNIDLVIMGSRGLSKFKQMLVGSIASGIISHSKCPVLVIR-- -> -MSRKKILVAVDGSEYSNKVLDKAIEYAKLL-GEIVFVNCHKRFGAEKLVKPFLQRFENENI-PVEERLMEEPAGTMISDIAKIEKCDLIIMGSRGLTNLASMIVGGVTNRVLQTAPCSVLVVR-- -> --MYRHILLAADGSKHSERAADHAIHLASMSNAVVDMIYVLDYAERRSRLLSIENKLKQAAV-PYQMTMQHGDPGPAIVSYANHHDVDIVIIGSRGAEHFAGNGARK----------CQP------ -> -MSFKNILVPFDNSSFSKRAFNLALDIAQKYDSTIIVVSCIDLLARKQLLKEIIPLQTKKGI-PFKKIIESSSIGRALLSFAKTKNIDLIIIGSHGKGFFDRLILGSITNRIIQQSHCPVLVVK-- -> -SFFKKILIPADNSKYSIGAARLAIQLAQLHESQLIFLHVVDVRSGWKVLYSLEEEA-AKHV-QVALTLEEGTAQRVILDVAEKYSVDLIVMGKHRKSGSKDVVLG----PIIENSECPVLIAK-- -> --QYSNILYCSDFSEEAEMAFHHAVDFCQRYGAQLHMLHVLHSGQAESLKSRYGDRL--ECN-QAVFAVRVGVPFVEIVRYAREHKVDFIVMGASGSSELDKQTFGSTVENVARRAHCHVMAIRN- -> --VYKRVLITVDGSEMSKTVFERGIEIAKREGSQACVIAVVDTTALKKFISELRQYC---DY-GFDEEVRTGVPSKEIISYADQWGADLLVVGSYGKGGWIEFLFGTTAERIIRTAKSDVLVVKC- -> --MYQTTLVPTGEGVAALDAVDDAIDVTAADGTV-HVLGVVEEIELEAAVDRVATAV-DAGI-DSETAVESGVPAHEIAAYADAVDADAVVMGKRGLDAAAGDLLGSTTERVIRNADATVVSVPV- -> --MYDNVLIATDGSDATEGCVDYALEIADRTDAKVHALYVVETKYGRETVTEIVEQV-DRGL-EGDGVIKTGRPSEKIVEYANDNDIDVVVVGKQGHGAVDR-HLGSTAENVMRMVDDAATVVVE- -> --MYDTLLVGVDGSDFAQKALEHAVELSQAVGATLHVITVVDSTAKATLIENITKTT---ND-DITAEVRRGDPADALLAYAAEIDADLILVGQSGAGQLEATIFGRTTEQLAEQTQIPLTIVPL- -> --------------MCTR--GDGPIDLAATDSATLHALYVIETREGEAVLESVETES-ERDV-AFVDRIETGVPERVIVEYAESEGIDIVVLGSRGKSAFKAVLLGSTSEVLVRDLSIPVVLVSE- -> -PVIHHVLVPTDGSENAERAVRFSAQVADRRQAEVTVVFVHLLVRAQEIVDRAVEEVR-GLVTTVTRVVIDSQIDEGILRVAEETNADIIVVGTRGLSPLRGAIMGSVSHSLIEKARCPVLVVK-- -> -IQYKQILVPIDGSENSCRAIAAAVDMAELSA-TISILYILTFSFAKSMLKDAGKLIP-KHI-PRHTYYEIGEPGIAITDFAQRNHYDVIVIGSRGLNFLSGIWQGSVSKYVTANAQCSVLIIK-- -> -LDYKRILVPYDGSEYAKRALDRAVSVARCCGAKLFIATVSRPMPGQVILDDSEKLIP-EDI-PHELIFRVGNPGSVLLDLSFEKNCDLVIMGNRGRGALKSLFMGSVSSHLASNVKCPILIIK-- -> -KSYQHILVPIDGSDHSKQALQHAIDIARITGAITLLSVANDIINSTGLLKKFAAMIP-ASL-SVQSIFELSAPEAAILAEQKSQSADLICMGRGGGQALKNFLLGSAQHLRHHPRTLPGPLGP-- -> ---MDKILLTTDGSENSLKAAEYVAGVLKKLNTSIVVLTVIPRDRSKFIIEQTIKPLI-K--YNIETMIKVGVPGETIAEVAQEIAATHVVMGTRGNTGLKGLFLGSVAQRVMQLVNIPLTLIK-- -> ----MKIVIGFDGSENSRKAVNFLGNFCHTMEIFI--VNIIELQETRKIRNEICKEK--SD-KDI-KIIESNRIAPAIIDFAKAIEADLIVVGSRGLGQIKRAFLGSVSSELIEKSPFPVLVVK-- -> -MVFEKILVPYDNSPNSKLALKKALTLAALTKSNITIVHVIAYHHVKKFLDDAKKEAH-KK-NKTEEKILYGNPSEEILGLMKKKKFDLVIMGKRGTTKLTGPSLGSVSNALVQTSKVPVLIIS-- -> ---MNNISVAVDFSADTPFIVDHALTLAKANDSKIHLVHVVGANQVKGELRKLVDFIL-DA-GEADSALVEGSPAPSIIHEAEHVDADLILMGARKHGLVGGAL--SASQGVLRQSTIPVYFVP-- -> -QPIKKILLATDGSVSSVRATKFCVGLAKKINAQVLAAYVTGQ-PSEAGLA-AKAFGQKNGV-EINTTILRGSVPRNLIKAAEADNVDLIILGDSGRSGFSKISLGTVAETVMRLSSCPVLIVRA- -> -AGFRKIVVALDFSPASERALALARAQFPG--AQLRIVHVTDARTLEDA---DASRLDRRLRDGEEVEQLVGDPVTGIVAAAERWGADLIVMGTHHQGALEHFFMGSTAEKVLARSAVPVLAVPV- -> -AMTPRILIAFDGSSPAGQAIVRAVEWVHGTGETIRIPVAIPPHFVEK----IRDLTEEHGV-QIRLHWRRGDPRHEIVQAATDLGADVVVIGSRGHGRISRLLLGSVSSFVVE--HAPVSTLVV- -> ----MHALITTDGSEVSIEAAQKAVRLLN---PTKITLLTVADTTARNAILDTVASLGVDPS-IVEHKVVEGSAGIMICLVAKQTNPDVVVVGSHGRGWFKRVVIGSVSEYVSRHCVAPVLVIRH- -> -PQVNKILYCTDLSKNASYAFQYAVYLARQTGADIHVLNVVEQLSREEFLHQIAPTEKALRTKIVGCEVVEGYPVQTILRRSRELGCDLIVMGAHEKGWLHT-LLGSVAKNVLRESRIPTLIVPR- -> -RVYGRVLVAVDWSRASDDCVEHGAVLARRMGAR-MCISVWETPR----------ARRVAGAGLGEVRVVRGNPGREILRYAEEEGFDLVVLGRRGGGVAHRFRLGSTVHRVVSCCSCSVVIVPP- -> -QSVNSVLTPIDFSENADTVFKAAVFLAKTFKAELHVVFVVQNFKMESFIAQHKGLCDEAGISAVSSKVLSGDVGEEVVKYAEQKKVQLIVMGTHGYKGLERIMFGSVAEKVVKTAHCPVLTLNP- -> -DEFDDILVPTDGSEAAYNGAQQAIKLAQRNAATVHVLYAIDMGKGQTFVAEIEALADDAGV-ETVTTVTPNTPLQAIREYVDEHGIDLVVMGKRGRSDPDKPLIGSVTNRAIGELDVPVFTA--- -> ---MFKVLLATDGSEYSEKAARYTGQLCEKMDDCEVTALYVKDIM-QEQLDTAQKVLARTGQ-QPILRSTWGRPSEMICRIAEEEKFDLIVLGRRGRGQIADFLLGSVSDRVSHCAKVPVMIVHE- -> -IQLSKILCPTDYSKTSEKAVRYAIELGRKTGSHVRFLHILQPEK-DDIVTELLMEEKKKGL-SAEVLIIRGNPYDAIIDQVRAWGPDMLIMGSHGRTGLNRLLMGSVAEAVFHAVDIPVLLVKQ- -> -DEVKKILVPVGFDAFTEKELEIAANIAKRYDAEVHILHVYQD-KIHSSVEEKLHQLVAEVRMPAKAVAIKGEIVDSIIEYVKNEQIDLVVLATHGRAGISHFFLGSVAENVIRFSPCPVLTFRT- -> ---MLKLLIPVDRSNASRHAVKHVIRRAWGG--EPHLLYVARS-SGVE----AAELLERGGV-PYVAHILYGDPAEQIVRFAETNRFGGIVMASCGLGSLPELLLGSVTAEVLRTSRIPVEIVPV- -> -MLYQNILVPFDDSEAALAGLKEACRIGLHTGAVLHIVHVI-DLIFKR----EFPNLNTH-----CTVLEAVKVASLLVHKLEEWECDLVVMGTHGFSGVKHLLMGSVAQDVIRQAGVPVTVIRV- -> ----MRL--RLES---------TSHDIAHGCIAAVYVISRLSHL--KQATQ-AEDLARMINV-PCQKIVVQGNPSIEILKSAREIEADLIVIGSMGRTGFEKILLGSVAEKVVLQSSIPVLMIKE- -> -MDLVRVLIPLDGTSEAEAVFDLLKGDLNSN-PEIILLQIVEPV---R----LKGLAEKYGN-DWRCEATIEGRADGIVKFASKENVDLVVMLQHKRNRISXLLMGSTADKVSKRSVIKVRKFTF- -> --MYDEILIPYDGSDEARKGARHGVELAAALGSAVHALYVIDLPYGEEVLEEVANMAAEHGV-DCSATIRSGSVSEEIVDYADEAGTNAIVMGSAYRGKLGNI-LGGAADRVVRSATVPVITHRM- -> -SHYKNVLVAIDGSAESRKILGKAQTLVKGSDAVLHAVLVYET-FQEQ-IASMLKAEFPQIP-ASNVHFLRGKAADEIKRLAKSLNADLVVIGSHGRGAVKAAVLGSTANSVLHGIHCDVYTVRV- -> -MWCSKILVAYDGSAPSAKAIDLARAIAAQDERVELVVHVLKLYEADRILHD---LQRTADVPNAHAKLLKTSPADLILKCAQDEGCDLIIMGSRGQGGVKG-YLGSVSYAVVQGSPVAVLIAKD- -> --MYQNVLVPVNGTEISETAIPHALELAEKHDAVIHALCAYNRERAQEIAT-VADRA-DEGI-EAVSAVSSGDPADSILDYIDEKDIDIVAIGARKRSPTGKLLFGSVTQTVLLHANIPVVVTGS- -> --MYDRVLVPTGVSGPDADGRTVGLDVAQRYDADLHV---LRIEVEERA---------FAGVN-VVE-AARGPPTDAIETYVDE-ESDLVVMPERGAFCDEPYRLGGVVGRYLRESPVNVMTVRT- -> ----MKAIIAVDGSEGSLEATRQAVRLHPQVDQFVLCY-VMRWSEAEVPMQKSTEIFTAAGLPPQRIERPLEGVARQIVLVAEEEKADLIIIGTRGRGDLSSMLLGSVSRGVIASSTVPVLVVPP- -> -TDGTLILLPVDGSETCRRAAEYCAWFARATGGRVLVLNVQPAFLAKT-----AALEILAGT-PNEFLMAEGEPAETIGRIAAEKNCTHVVMGTRGLGKVSGVLMGSVAMKTFHLVGVPITFIR-- -> --MSYKILVAFDGSDGSVNAANFGFNMAYYLPDVIIEITVFTFTKAEKINSI---FLKKTDNNPFSLSVLDGNPAKEIVKYAIEEGFNHIIMGSRGWGKIRKLLMGSVCKKVLENSHCSVTVVK-- -> ---MQKILLPVDIEKLSDKTFKITCDLVQKLDASLVILSVVPFSYAEKIVKDIAERFKLKDIN--QTVILKGNPADEIIRYSEEDQFDLVIMNTQNINSTKRFFVGSVTNKVVHNSNVPVLIIS-- -> -MSHTKMLISIDGSVYSEEVLEAGMEIAKSLDSRIYVVYVVHPGMGKDAFR-ATAIAEEKGL-SCETKMLEGYPSDKIMDFAERKSVDMIVIGSRGQQSTREFLLGGVAEKVIRNSKKPVYVVR-- -> ---MKKILAAVDGSPLTHNVIMAAVEECHG--AELHIVHVLENASLLS----MKAEAEAQGG-EAVLHLLRGHPGDRIVDCAIDIGADMVVLGSLGRSQVKRMIAGSVSTFVVT--HCPITTMVV- -> -MEITKILLPVDGSEYSLNAAAEALDLAKKFDAKIIVLYCSETFYANHVL--------KHQA-KFTEHVVDSSPSIEIPRMAEKENVDMIIMAPRGTNPLASILLGSVTTRVLKQAPCNVLVVHK- -> ---MKHVLLPIDGSTRSLRTIDMVQQTYRPQDTEVTLLMVLPDQ---DRMAR-FAAL--LGW-TVRTELLWGSPGPEIVYYARERGFDALVMTRSSRGPLQK--LGSVATYVVRNAQFLDLIIMR- -> -MEYERILLPVAGDGDVDPVVDHADSLAAALDAELLALHVVDPDRGPEAVFEAVADRVDETV-SMRRVTAEGDPGESIVDAVRDWECEFVVMGTHNRQGIDRLVTGSVAEHVTRTAGVPVTTIAV- -> ------------------MALEEAAELADKYQAALTAVYVIPQAEAKKVLADMTVTYRQRGI-RITEHVLAGGPHIEIIRLVERVGADLIVIGAHRAAGTKPVLMGSVAEKVMRQAPCSVLIVRE- -> -SPFRHLLVAVDGSQAALQALDTAAELAHAFHSRLSLVSVYRHFLAEEALLQAQTRLTQRGL-RADCHLRRGTPATVILELADQLSVDAIVLGSHAEG---DRLFGSLADRVSAQAHCSCIRVRG- -> -MSFEHLLFVIDDDQVSPTAIHHVTQLALAFNSRLTLMSVVSIDTEAKILAQLKHQMLQGIL-NIHTKVIHDPIATGVLTVADEINADLIIVAAKNRNSLKKILAGSTPNAVLAISPLPVMVIN-- -> --MFEKILVPLDGSENAFAALRAAFDIAKHYDSKIYAVSVANDQQAEVALNQAAGEAKDAGI-VLETHFEVGPKQAIAESLPERLGTTLTVIGKSGAHGLNRAIMGSTTAYVVRRSTVPVLVISQ- -> -MVYQNILVPVDSSEESFAAIQHAIEIAKAFQSEITIVQVLTLDRARTFIQANLQNVYNTNV-DIKIRLLEGSVTHTLINMVEQSKTDLVVISSHGRSGLKKLIWGSITQNLISELNIPIFIVKP- -> -MSYKNILVAIDLSKESRQIISKAKETAEVYGAKLHLISAIEPLEAKERLL---AITEDLGI-PSKNCFAPINPANEIRERAFKLKSDLIIMGTHGRKGIKKLILGSTANSVLNGTKVDVQVIRI- -> -MVFSKILVPVDGSSHSDRAVEYASEIALKFNSRLILLHVYSFI----TINILSEKAKKSKI-KNVTCLLREVTVPEILQVAETEKIDMIVMGARGVTGIKLHVL--------------------- -> -RRLSRILVPIDDSKPSMKALELAMDLAMKYKSRICIVNIIPTHEARSLLISTLL--IR-SI-GIESIMGKGHPASEIVRIAKEENIDLIVIGSKKPSIFAG-LFGNISRSIISKAPCPVLVVK-- -> -MDLRVILVPYDSSHFSENALEYAVYLAKAIIIKIVMLHVVQEILMQNDMDKKKKAYSIEGI-KLESLILYGDPSNQIVDYSNNNRVDLIVMGSNGLQGLAKKGLGSVSRKVSESVSCPMTIIR-- -> -TGKPSILVPYDATELSIKALDKAIEIASRMGYEILLLYIIDDTGAEKCMTEVVGKIKEKEL-FVKYIIRVGHPDDEILEVSKNPNIHLIVMGCGSFKKRHNRGVGSISRWISEVASCPVVLMR-- -> --MTKTIFVPHEDNEASAKAIKYAIEIAKGLNMEIKLVRVVPEVQEAEKLQKHVSKISK-GI-KASATVVEGVNAEKIADLVRQERPYLVVIASKRRGSLAKRMLGSVARRISEESTSPVLIVK-- -> -MTFNTILVPYDGSAHALKAFNKAVELAKQHHSQIKVVSCLNIAKAKKLTKDLFSKLKN-SV-SVDFKIIESNNIKSLMLFTKSKNVDLIVMGSSGRGGFDK-LLGSVSNGVMQKAKCPVIIIK-- -> --MISKILVPIDGSPLSKKATQKAVELAGQLDATIVITHIMDQKNAQDIIKEMVDYVSE-DV-AVESMLLFGSPEYDIEKVARKSEADMVVLATHGFGLKSK-LLGSFSNAVVKYVKLPIVLIK-- -> --MYNKILLPVDGSKNSEKAIKHATTLAIDEEAEIVILYVVDHRQGEVVTQRVVDQINGKTI-KTEKLIVEGNPANIIIKAIEKKDIDVVVIANSGKNFVDRFLIGSVTERIIRCSTVPIVVIP-- -> --MFQHILLATDGSESAHKAEDYALYLGGACGAALTVLHVQEDRTGDRILREFSRK---RGV-PYTFKMKQGVPADEIVATAMQEQVDLLIIGGGHAGWLKGFRCRGVADKVTAMVPCTVMTLS-- -> ----MKVLLATDGMPHTDRAIDYAIDYASRYRAALFVVYALSPGEGKETVQGIKQK---REV-GITTMLEAGEPAEAIVRTADKIGADAVILGASGKCEGRKRPLGSVSARVVQDACCSVFIIR-- -> --MYNHIVAAIDEARTSRLALKHAVELTRLSGAQLTLLTVVNPTEGEHILNEAEQYARHEGLVIIISTKGVKDMAEKLIRKAEESGADLIVLGTHGRTGLMHFLMGSFAETVLRQTTLPVLILRSR -> --PMNRILVTTDGSELGQHALSHAQGLAKALGAELIVLSIQTDPEMKASLENLLHER----VPIMVERAQGRHVSRAILDVAREEGAQMIVMTTHGRSGLGRALMGSVAQAVAQHAAVPVLLIKGD -> --IIEKILVATDGSDVAVRAAQMAVVLAHTGARRMVAVSVAQPQAARAHVETVARIAKSGGVSCEVLVKLASSPGPEIVQTAEDYECDLIVMGSHGPSAVERGYAGSVAQYVLARSAIPVLVLRDP -> --TARHILVATDLSPSTGPLFAVASSLVRP-GAEVIGLHVYTPE-----RAEMRFQADQAGIPIRFEIVEGWSVPEQILSAATRFGAALIVMATHGRTGLRRALMGSVAEEVLRRAGTPVLIAPTA -> --MFKKILLPTDGSALSAQSANAGISFARSTGAEVVALYVTQPFLAQKHLKAVADRAETAGVKVSAHAVSNFNIADGIVQAGIDYHCDMIFIGSHGRSGFSRLLLGSVTTKVLALTHSPVLVYRVK -> --MFKHILVPIDGRPAMKEVLDKAVVLARTFGSRLTAVYVLDPQAGEQALQAASLALRAAGQPVETAVVEEATAWRGILHAAAQAQAELIVMGSSRRKGLEKLVLGSVAESVLQNTTIPVFVVPST -> --MIKKIMVATDGSELAEKAAAYAIDMAKQLQGELLALFVMDDSIGEEAIARVREMGKEKGVKVSGKLIGSSSAVQGIIEAAKEEKVDLIVVGSHGRTHFLDVPVGNVTRKLVARKPCPVMVVPVS -> --AYRSLLVATDFSSCSRRALATAADMFPD--AALHVLHVYDVPQARRDLEAFLDHPDLSQINRISIHLGHGVMDAVVEQTARDVNADLFVLGTHGETGFLQFVVGSRAESLLFWSRIDTLIVREV -> --MFTHILLAVDGSRQTPRVVALAAGLAAASGARISVTCCVDASAAARIVREAAQLH-PLGEK-VTGQVIVGDAAQALVAEATRQEASVIVMGHRHRGLVDRLLKGSVCADIMATAPCPVLVEVRD -> --MFEKIMVATGGSPWSNNAVGTATRLAADINRELHIAHVLEDDTGRSILQQATERAEQAGV-TYTTHMVWGSIPEQLVHIAQTEGCDLIVMGTRHLTGDKRLMTGRICNAVLATSPCPVLVVPLV -> --EGIKVLVAFDGSKESRNAVSEAADIANRFHGSVTVLNVYWDPDAEPILKEK-------KAEYSLRPERDSNVPKTILRIAEADGYGCIALGSRGMGGARAWLLGSVSSKVIAEAPCPVIVA--- -> --MFKKILIATDGSEYAVRAAEVALDLAHKTGARVLVLSVIDAGAAEGNVEYVLRLAADVGV-EATGHVLTGRPNIEMVNLTNSEAADLIVLGRHRRRSIGRIMRSDLAVRLMEDLDCSILVVV-- -> ----MKILVPVDSSDAALAPVARLQALARSGIDEVLLLNVQPRFRSRAAMARAIEALSLANI-RFRAVAEVGQPAERIAAIAERERVDEVMMGVGRHPEWLRWLNPSIAQGVMSRTDIPVTVLAR- -> ---FRRILVPLDGTKLGEAALPYVEELASITKAVIL--LQVVKPAASEYLNSIKEGLTKKGI-AAQAIVDVGSPAEKVMACAREKKIDLIALSSHGHPGVGQRTLGSVTYKILHYADRPVFIVTP- -> ---FNKILLATDGSKNSLHAAKTAINVAQSTQNTIYIVYVIKFSQRQEKIQSTVELIKASGI-NYRTRFLRGEPGSALVKYANEGYFDLVIVGNGRKNKLQELLVGSVSHKVAKGATSPVMIVKA- -> ---MKTLLMAIDRQAMAEKVINVTLEQAKAHQAVIILCCVAPDDSAEQIVRYALNPFAEAGI-PARGMICCGDPATTIVDQADRLNVSMIIMGRRHLSAFNRILKSSVSAAVLERAHCPVLVDVS- -> ---RDRVLVLIDFSESCFQALEETMQEMDNPESHIL--H----VRVKKAFYKRCGTPPY--E-KAPFTVLIGKPAKRIIDYAKENKIQLIIIPSHAHKGLNRFALGSVAERVVRQAPCPVLVLRE- -> ---FNKILVCLDGSKESEKILPYAEAQAKAFGSLCL--VESVGLLAVGYLAMKAAELRSKGL-KAEYSVRSNEAGESILDCAEEGGYDLIALATHGHCGLVKFLSGSVADHLLHKSNVPLMIIKS- -> ---YKKILLPTDGSEFAEQEICKVKNVLDPEGE-VVIVSVAMKIESEAYAEHMKVQLEK-GV-NSKIRVVCGRPAEKIEQVASEEGVDLIIISSSGKTGLHKFIIGSVAEKVLSIAKRDVLLVHE- -> ---FDKILLPTDGSEFSEHEVERAIKALADDGE-IIILSVASKLEAQDNVDRMAARFDE-RV-NVKKMVVKGIPSDVIVDVAEKEDVDLIIISASGKSGLHRFFIGSVAEKVLKSTERDVLLIHN- -> ---MAGILLPVADMKYDKKAFDTAIEIAQKLNLKITLINVQNIDISKKILENAKTFFEGKDV-EVDIKTEYGDPAETIIDMAEKQEFDYVIINSHRIDSKKRFLLGSVTNKVVHHATRPVLVIK-- -> --PLDDILVPHDTKKESVAAAGHAFRIAQMFDSTVHGLYAVESSQGDAALTQMADRAESRGV-S-VREIRTASATQAILDYAEENDIDMIVMGKGRRKIDGPSTIGGDLLHVLQWTDIPVLTVSN- -> ---MERVLLPTDGSDCAETAAGLASRIASDYDATLHVLHISETVTDCEAIQRIHQQARGYGA-EIEAAISSGYPFREIVRYVELRDIDIVVMGSHDRTGLGRVLNRSTTKNVIRRSPAPVLTVPQ- -> --STERVLVPFDFSDEASAALTNTLEFVGDASRVLHVLHRLETTDTRRNVQKAFHEQPPEGL-R--FDMAIGDPSSEILDYAKGNNITLIVIPSHGRSGLGRFFLGLVAEK--------------- -> -AKDRPILVAVDFSDDSKAAFTWACEAATAFGAPIVLFHVVHEPVAEKMMRKFLKERSDALK-NLKTQLVTGLPVTRVLKAADKVNARMIVMGSQGRSGLAHLLVGSKAEQVVRMAKIPVTIVKAT -> -FAPTKILVPIDFSVSSQAALNTATGLAQHFHAEIYLLHAIPMIFLETALSEMASVLTSLGI-EANFGVEVGNIVAPVLMVEQREGTDLMVISTHGMSGWRPMIFGSTAEKILKLAQCPVLLLRSA -> ---MRRILVAVDGTQASREAARTALEYASGMSSRVTFVHVLPERYAEALLKETCANTQSRHPG-ANTLVAHGEPAAVLSELAEEEDVVLVIVGARARGSLARTLLGSVSGELMCRCPKPVLVVP-- -> --MYHKILVPVDGSYRAVEAAEYGIELATQVKGQVTLCHVIPATNGRSLLERMHDVLLRDGIN-LDTVLLQGNEAYEICRQAREGKYDLVIMVGQASG----YLAGALTNRVTQNAPCPVLVVR-- -> ---MKKILLATDGSDSAMHAASVANQWMEAWPAKLEMVYVTQVYRFTA-----AFEGKLDRVA-FSHVTDVASPAIVLSRIAEQDNFDMIIVGSHGRSAINRMVLGSVSHGLVNRAKVPVLVVR-- -> -LPKRKVVVPFDFSEASRKALEVARTFVPDAGGTISVIHIIVPPPMARGFTVLR----DAGV-P-AHVRVASNPAEELVAFAERDRSELIVISSHARRGFDRWLLGSTAERVVRLAPCPVLVLRGP -> -VPFRQIVVYLDGSESSMTAIMYGIKLAKEHDAKLMAVYVINTRALEDDLQQDARLASQKEV-D-ETVKLEGAVHIVMKELLKTQKADLLVLGGITDIRSRREELASETDRMMRTSPCPVLVVRDD -> -TRYQKILVPLDGSGWSQRALPHAVDIAMSNKSELILLSIFSAPAQYDSRILYLE-LRESGI--TE-VVDGSDAAASICNYVRASNIDLVVMSTHGRTGLARMIFGSVARAVMECAQVPTLLVHPD -> -PTYRKVLVTTDLSPTGNSAIPHAYAVLAGLGGTVILWHAIDLS---ASLFSSLEEARAEGR-VTRVVEAPGVIQEAICQDARTQGADLIVMASHGHSGIKHLLLGSVAESVLKSADRPVLVVLSR -> --MVTRIIWANDGTLSADRALPVIKDLIASTGASLTVSYVHRDW--LPL-RRRV----AEGF-DALHDNDGGHPAQLIADLAQDEGADLIVAGSHGRGPVAGLLLGSFTSHLLKVAHCPVLIVPWR -> --MHQRILAAFDGTHEAHLAVEEAAALARAFNGRVRVVWAIGSPTMERSLVELQ----ADGT-LATGVLMDDDIGNALELEAERWQADTIVVGSQGKHGLARLLLGSVAERTTRLSHRTVVVVRAR -> -AGPSRILVPVDLKDGSRSVVDYALQLARPFGATVDVLHAWEPPQYATLEALLRKVDGTAPV-ALSHRVVIGEAGNVVLEEAERGKYDLIVMGTHQRKGLTRMLLGSVAQKVVGRAACPVLTLHVS -> -MPMKKILLGADGSDHSKHAARYAVDLAKAFGKVL-IVTTYRGQTITRRQSWYQ----KNDV-P-ESHILDGPAAEAIADTAQRRNADIIIIGSRGRSNLVGMIVGSTTNALMHIADCPVLAIRLK -> -ETTKPVIVPIDFSGMSVDAIKTALRLAA-DPKSVHVLHVVPVLDQGSHFREFLAEHGFTHL-R--EIILQGQPGEEIAEYAAKVEAGVIVIPSHGYHGVKRLLLGSVAEKVVRLATCPVFILRRD -> -NKSSLVVVPIDFSDNTPAVLEKALLLAG-SPDDLRCIHILPNQAGSDYFKEHYQEYNISPS-Q--FEVRLGSAGFAIADYAEEINARLIVIASHGHHGLPKLLLGSVTERVIREAHCDVYVIRCP -> -MATETWLVAHDFSPCGDAAAKEGARVVERLGGKLVLLHVHPLPQL-ERLQGVAR----YPK-VEDVVPA-RDPARGIVEEAARLGVAHVVVGTHGRKGLEHLVLGSVAEKVAKEAAVPVTVVRQT -> -MTSENTVVPIDFSDLSYAALDRALEISS-GTGKVHVIHVLSALSTEDHLKNKLTGEKYRDV-Q--IHVTIGDAGREIANFAQKVAAELVVLSSQGQGFLEHLLVGSVAERVVKLATCPVLVLRA- -> --------VGYDGSAEAQHALHVAIALAADLHGDAHVLLVVRPPAHEA-LSRGLQ-TQHRWE-VS---VYADDPALAIAGYAEEHGFDLVVVGGHGREQMTHRGIGQSLEALLRHHPCPVLVV--- -> --MSQPVLYATDLENGSDVVFRIALQ--MLSDAR-YFLHVFEETR-LLMQQRIQHILEPFDQ--I-ELVSFGSASQKIVEVAKNKDVSMIIMGDRRVNALSRFFLGSTAQRVIHNAGVPVLIVPI- -> -TQVKNILVPIDFSTSSYQVFELGHCLAKHNGAN-HLIHVIDPVYER---ENAKEELRVPHS--I-IALIEGIPHKEILSYSRQNDIDMIVIASHGWTNLSHMLMGSIADKIMRQSDVPVICVKS- -> --MLNHILIPLDQSELAETALEYASKLVVIVPPD-SFAALYNP--PQ----DYLRRVG-KGV----DLVQVGQDAETIVENAANLNVDGIVMATHGRSGISRWLLGSVTQKVLGAAHCPVIVIPN- -> -FGFDRILVATDFSPNSVRAVRYSVQLAKRLGAR-TILHVVPEPAS------AAKRLDREYA-KD-CQRTAFSPRDEVVKVATELPADLLVLSTHGLTGWKHFLFGSYAEKILEHAPCPTAIVK-- -> -KQFKKILFATDFSTNAEYAFDVAVTLATKLRAK-IMVHVVPKPDRQ-KREATAAMN-NAEN--F-EKILFGSPYEEIMKKADEEKVSLIVLGKHGHRETEHFFFGTTADRVVKMATQPVMVVRH- -> -LQIQRLLIPVDFSNSSRRAFYTGIRFSRIFDAE-HILHVPDSIAD---ETGVRRRINKGGI-AV-KSILGGKPHAEIVKFACSNDVDLIVMGADGGSGVKARVMGTVTERVVRDSPCPVLCVKP- -> -PKIKKILYATDLSETAKYAFGYAADMAENYNAL-TIIYVMENMPI-YLKQKIKARLECRLL--VEDKITRGNPAEEILDISKEISADMIIMGNHGHNIL-DAVLGGSARTVVKNSEIPVLVIRL- -> -PQIKKILYATDLSDTAKYAFGYAADMAKHYDAM-TIVYVMESMTI-YLKQKIKSKIECRLL--VEERIPKGNPAEEILNASKEIHADMIVMGNYGHNIL-EALIGGSARTVVKNSEVPVLLIRV- -> -FEVKRIVVPLSLCSHSELAFHLAHDLAERYDSE-CAIHVF-----ELYDKIFRQRIDGRCT--T-RIVTHGPYAEEIVREARDIKAHLIVMGTHSGKTLQQNLLGSTMTRVLKQTPCPVLAIRY- -> -NTFGSILVPVDLGGS--RILRTAGELAEAMDAS-SVLHVVQPML-YTIEDRARSAME--GE--A-AQVRTGTVGTSILDECRSGDYDLVIMDSG-EDHLLTKLFGSVTDKVVKNAPVPVLVLRG- -> --MFSRILLATDFSEHSEQAYPWAAQLAASNGGT-VLVNVLEGDVN--FEKAAQTALDALGA--TH-LVQGKRASETLVQAAEDLDCGVIVISTHGRGGLAKFLLGSTAEKVVRTAQRPVFTIHL- -> -IKINKILVPVDFSEGSALALRYAATFASEYGAQ-HLLNVIEEEMA-QNHKRLEEFVPD--F--I-IKVKGGLVHECIIEYARENEVSLIIIGAHGQTGFIDSWLGGNSYEIARKSPCAVLTVKP- -> -LKVLRILVPVDFSKESDLALEWAVMVARKTSAT-YALHVLPLPEK----------VEKIPG--S-MILEKGRTPDVVTRICEQKDIDLVVMTTRGRRGLKHFLPESTTEDTVRRAPCPVLVLHL- -> -KNVKNIIMPTDFSRLSLSAFELVKQISELINAE-HIIHVAETNPIM---EQTREELERDET--I-KVLLTGLDFEEIVKYAAELHESLIVIATHGRTGLMHTLMGSVAEKVIRYAKCPVLVVPH- -> -LRIQKVLFPTDFTGASIHAASYALSLAEAYKAK-YVVHVVDTSERE-MESATEMLR-RFKG--L-ERVLDGEPYKEILKVINGSAIDVVVMGTFGKARIDRVLFGSTTERVMRKAACPVFVVPP- -> ---MKHILVTTDFSEEAGSAFDYAKEQFKLSGNEQTLLKIIDVVP--AYKQASEKIRQ-AGL-PTV-IKPKKSVYHEIIQFAKSSNVSLIVMSTHGRTGVKHFFLGSVAERVVRSSPCPVMIVPA- -> -GRFERILLPVDFSSDCDVVAHHAAWFATT-GGTVHLVHVIVNPDLL-LRAVA----EL-PA--VTRHVRHGDAYEKIRAVVQEIEPDLIVLSTHGRGGIAHLLIGSVAEKIVRHTPCPVFIVPR- -> ---MRHILFPVDFSTPCENLVPAVEAWAKRYEAD-TLLHVHELPVPL----ASHQRLNFAGL----RIQVDGRAGTAIVDYAKANGIDVIMLPTHGYTRFRQLMLGSVVASVLHDCELPVWTSAH- -> -TKPSRILLAIDGTQGSYRAAHHAALIANLTGAE-ILLHCADPHS-T----RLGPARDDSHV----MHTVEGPAAETILGMALRERCDLIVMGRHGTGDTEELPVGRTAEHVVRAAPCTVMVAA-- -> -IVIEKILFPVDLSESVNSFIPYVVTMTRKFNAT-YIATVTPDVSTE-QQGAAHHIK-RLEG--V-ECVLVGDPADQIIDLARQEEIDLIIMGTRGRSGLQKSIFGSVCDRVIRSAICPVFSISP- -> -LAPKTIMVPLTAERPARLALRAAGQMARELGCR-ILAYV-SP---I----RLEGALGFGDL----EVARVDDPGDGILALAREHGVDLIVLETRPRSLLERVFVPSVAAKVVHHAPCAVLVLPA- -> -SRGQLLIVGIDFSEGSAAALQRARQLARHLDGR-ELLHVSDAA-------EAGGFDA--------ENVRQGVPWVEIARRAAEAGATLLVVGTHGRSGYQPLAIGATALKLTLTAPCPVTLVNA- -> -MIYQRVLVPVSGKNSGERAAKALRHAKTLCSGE-ILLHVTEA---K----TLLSPLV-EGV----RLVREGLVADTIVTVGHEEGVDMIVMYTDGRDGLADMLVGSITERVLRNTDIPLLAVRR- -> ----MKVLVATDGSERAMKAVRKSLEMAEKEGAD-TLLSVGYFLSV-ALDADSRTALEEKGI-KT-TMEKGLVPANVILEVAREGRFDHILLGSTGKTGLEKYLIGTTATKVVANAPCTVTVLR-- -> --MTLRILVPIESLDDTHPALETARRFFPGA--E-HLLHVVIPGIL-----ESVAQVDTLGG-----LIQMGDPATEILHRARSGDFGLIVMATSGKRGLQRLLVGSVAQRVIRESPIPVLSVRQ- -> -VGYDALHLNNSEQSVGKKALEVACKFAKENNAN-CIMASLEQRN-E----KVKNHLDFESL--T-LSVNYFTPGEDLVNFAKDNGIDLLFVGVRNRSKVSKIMFGSNAQHIILNSPCPVVTVR-- -> --------------------MELACRLGAEQGAT-MLAYVI-----EQTAGAALGRAE--GL--Q-RVARARVAGEEIVRLARESAADLIVMGIRPRIGLRDEILGRTSDTVLRRAPCEVLLDKL- -> -KDFEEVVVAVDGSDASIRAARVALRLARDLDAPLVLLHVFPMMSARQAFSDVRKELGEAEV-EIREEARIGDVGEEIIDYLGDAPDRMLVMGRRGQNAMSALLLGSVSDKVIRHSRSPVTVVG-- -> -MVFKRILLPINKIDMPVNIIKKTIQLAKQLKIKIKAVYVHNTTKAYAVLKEIKKMGEKENI-DIQTILIEGIPEKEVIN--EAKKNDLIILNDEGTTTLDRIFSSSFSEKILHNVPSAVLLVK-- -> ----MRILVPVDGSDASLNALRYALGLRDVHKEGIHI-EVLNVQQGEEALIAAKAMVDEAQA-DYDVSIVVGGVAEAIVEQAHEKACDAIVMGRSGLEGVAELLLGSTTNKVLQPQISPLRLFPD- -> --MYSDILVPTDGSDSIEQVLEHTIDIADGRNVTVHALYVVDDREGRAATADVEAALEEAGI-SVTKTILRGRPADHIVAYVEDAGIDLVTMGSQAGEYE-QNMLGSTSQKVVTQSPAPVLTVDV- -> --MYRKILVAYNGTPESRCALHACIRLAPGPEVEVHLLGVINLALLEQELTKGHKLLSDVGL-KVITHFESGEPINVIGDLVTQLGIDLVIIAHSRKKPMARWWRGSTDSLLVEKISCSILVASD- -> --SLDNILVPHDTRKESVAAAGHAFRIAQMAGSTVHGLYAVESSQGDAALTQMADRAESRGV-PFVR-IRTESVAEAILDYADEHDIDMIVMGKGRQKIDGPSNIGGNLLHVLQWTDIPVLTVCNP -> --MFDSILVVTNGTDPGSRPAERAVALAETHDAELHA-LYVVDVAAVEF---VANRGAERDV-P-VVKFRYGRTHEEIVDYAAAHEVDLVVVPSTTRRGLSRMLPTDLAERVIGRTDVPVLGIDVA -> --AYHCIIVPFDGSDHAQSALNAACGIAKGHDTQVHVVNVVPINIHAEMVNTIGDASELDPS-QVTYEIAHPSAVDGIIDYASDHSCDLIVMGRRGLGAIRGLL-GSVSYGVIRATTTPVLTVK-- -> --DYQTILFPTDGSDSSNRAIEYGLDRIVEPETVVHV-LYVVRPVAIEEFVDRVQRKDETGI-E-IEHIRHGIIPEEIVQYAADQDVELIVMGRSGHTVLDRFTLGSVTERVLRAIGTPVLVI--- -> --MYDRILLSTEGTVASEEAETHALELAAAHNAVLHVLYVVDEDHGEQTLSELRHRAAETDV-DVEMSMQHGRPAETIVNHADNCDADLLVLGTKRRPDEYRALLGSVTDRVLRLTTRPATVVKTE -> --IYNHILVPYDGSDLSQKALFTALDYINY-DPKITVLNVEE-S-SEELIKDIEQTGPIDG---RFNVQMTGKPDQVICEYVDSHNVDLIIMGCRGLGAVRAAF-GSVSTAVLRGANCPIFIIK-- -> --MYDRVLVPTGVGDDAERTINCALDVAQRYDAELHVLRVSDPEKRPEISNRVGERAVAGGV-NVVS-VRCGPPVETIREYADESE-DLVLLPDRGGFCDESYRVGGVVGRCLRECSISVMTVRAE -> --MYERLLLPVGEKASPDDRYEPVFDLAREHGATIVVLSVADTNEATDAAERFADRAREHSV-RVET-VVQGTPHEEVVAYADAREIDLIVMRKRERGRLQEALLGSVTDRVIRLTDTPVLVL--- -> --NRGEILVAYDGSDSSRRAVEFAAERAGKTGEAVDIVYVGGDR--DEFLRERIV-ANFETI-Q--MNTGNEAIARRLAEYIRDHEYTLLVMGNSERGRLYNAVRGSVTGELIEQRPLPILLVPAA -> --MFKHILVGFDGSESSRRGFGTALEMAVRLGGALTVMQVLATYAAQREVAALTDAAEARGV-PCRTVEFAAEPHQALLLQAQRDACDLIVLGGGRDERGGRVPPGRETASTLVRGSIPVLVVG-- -> --MFRSILVPVDGSGLSNKPVQTAIAIAKMHTATLVFLSVAEPRAARANVQKAVNASTDAHV-PCEAVTMSRIPCEEILETAARYQCDLIVMATRGMGVIDTVFKESTTQQLLTKAEIPVLVLP-- -> --MYRHILVPLDGSELTTSLVAQAVEFALGLGARITFFTMVEDYRASTVISKAVAVGQAAEL-ACEGVRIGTDAYEEILQVAKEKECDLIYMASHGRRGLKALALGSQTHKVLTHSHLPVFVAI-- -> --MFTHILLPTDGSEQCRKAIDGALKLARATGCRLTAYTCIEEFYAKDCIDRIAERAQEEGI-QFDSDSQFSEPYLGILDAAKRHACDVIFMASHGRSLMGRLLIGNETRKVLTYAQVPVVVYR-- -> --MFKNILVPIVDDMVTPKSMKMIADLVEQDGAALTLAYVSDPRHANELLAKAAKMI-GKNV-SLKTLEYNATVYEGILAAAKKAKADVIMMASHKRTGLKGVFMGSDTHAVIVHSKLPVVVCI-- -> --MFKNILIPVVDDMVTAKNMKVITDLVKADGANVTLVYISDPRHAKEILEKALKLV-GKEV-KAKVHEFSATVYEGILESAKKAKADAIMMASHKRTGLKGVFMGSDTHAVIVHSKLPVVVV--- -> --MFSSILWPVDGTPLSFTPMQTIINLAKLSNATVAVLSIAEPRSARREVDKARAAVVQAGV-VCYDLALSALPSAEILHTAEQRGCDLIVMATRGMGVVDTLFTTSCTQEVIEASKVPVLVLP-- -> --MFRHILVPTDGSDQAQAAVVRAIEIAKEISAQITVLTVSEPFNAATVLGRAKVAASAANV-NCSTILQHDSVYRAIIETADQRGCDLIVMTWPRRHTMLSHWHESKTVRVLKYCTVPVLVL--- -> --GSMKVLVCTDGSELSEKAIEAAVGVALPLKAELIGMTAVKGVEVQKRLSVIYEAAKAAQL-PCRVMIHGEAPWQCIIKLAKDEDVDYVVMASRGMGSIGSLFIGSETQKTLAQIDRPVLVVR-- -> --LKDVVQVCTDGSDLSHKGIESAVEIAKALHLPVVGMTAVLSKAVQERLAAVKNLAEAAEI-PYELVEHCESVADGILNVADRHDARFIVMASRGLGTLGSLILGSETQKVLAQADRPVLVIR-- -> ---MSKLLVPINDSNDIECALKHVIER----QGTLFLLNVQTPINGMQILQPMIDGLDAAGV-PHQERVVVGHKAESIVQFAREHHCDQIVVPKHK-SVFENLGLGSVGSQLRQLIGAEGICDI-- -> --SQTDVIVPLDESVASESILPFVGDFVRAWGAGDTRIILTNVCNAQQYLDKIKVNLTEQGQ-NV---VLIG-PAEEIVNLASNNPFSIIVMSTHGQSGKDKWVYGSTTERVIVGAPCPVLLLKPK -> ---MKNILVAIDFSNATDAVIHQIGKLACPNDSIIHLLHIVEPSIAKNHLQKTAEKLSRLDA-TIIQAVEDEFESEAVINYAEKHHIDMIVVGKHNHGFLSTVFLGSVASSVMRKSPVPVLVVPVT -> --MSERILMPLDGSQLGEAAISYIDGLISRLTVEITLFHVVTNVEAMAYLERVSSRLKKEKI-GVACKVAANNPAEAILEAKDEVKATLIAMATHGRGGITRFAIGSVADKVMRSSEVPVLMVRSS -> --MYKKILVPLDGSERAEAVIPHVENLVKHDETKVIFAQVVESGQVKQYLASWKDQFRAKDL-SAKILLLRG-AVEAILHAGEITQAELLAMSSHGRTGLARMFHGSVAYGGSTESDALSCWFAQK -> --MFEKVLVCLDGSALAEQILSYIAGDSRSFKKII-LLKVIAAPETPDYLESRAQPFREIGL-DVECVVLEG-PTKAIIDYAHDSDVGLIAIATHGHSGLRHITMGSTAEYILKHAGLPVLMVTPK -> --MYTKILVPLDGSEFDEHVLPYVKWFVKVSEVEIIFLRVVEPLLAEDYLVKLAGQFRRGQL-KIKTAAVIG-PARAIAEYVGHSRADLIIMATHGFSGLHRLVSGSVAAELLHNATVPLFLVTPR -> --MYQKTMVPLDGSELAEYVLPHIAAITEGGVREVIFIRVVKPFAADGYLDRLVIRVSYDKT-KISQTTILGEATGSLVDYATNNKVDLIAIATHGRSGLSRWIWGSTADRILRHTRVPIMMVRVP -> --MYKRVMVPLDGSELSESIIPQVVSVVKPSNATVVLFQAHEAIDAQSYLDKIAGDLANQGI-NSEIVLGKGRPAEAIIQYATTHAIDLIIMATHGRSGISRWAFGSVAEKVFRQSPVPILLGPVA -> --MYRKIMVVTFGTELSNKAVKEAARLAHSVGAKLLILHVRSPLQERKLLEGAVGIAASFGV-EAETAFIADAAHEAIVRVCQEQQCDLIVMATRIHRAIPGFLVQSQTQKVLAKTSTPVLVVR-- -> --RYEKILVPLDGSRQAEYILPQLEAMVKAFDADVTLLHVVADKDITGYMEHIAEALRGKKV-RCEWQLTHG-PAEEIAKFAATDMADLIIMTTHGQGTTKKVRTGSVAMEIISSNQIPVMLVRPP -> --MYRKILIPLDGSVEAEGVLPMVRGLVTP-ESEVILFQVVSAGEAIRYLRQVLGKLGEPEG-QW---AVFA-AADGIVDYARSEEVDLIAMCSQDRKGLSKLMKGSIAEKVRKKTATEVQVFKPG -> --MYTRILVPLDGSPIAEQALVHAAQMAEIFDAELILLRAAFLAESEDYLDNVARRLRGHGR-RVQTEVRWSEATEAITAYAVAQAVSVVVMATHGHSGFEQWPMGSIAEKVLRSMQVPVLLIRPS -> -NKVQKILVPLDGSKFSIRALNYAINLAKFTHSKIIGIFVIPSDLGHKILEQAENRCIQNKT-PFTKIMSSGNPSIVIVKYTERNNIGLIIMGSRGRGHAGEILLGSVSYNVIHKSKKPIMIIK-- -> -SMFSHILIGVDGSKESFRALSYAMTLAKQFNGTCDVMYSIPPREENHIRDLVQDIAAKEGL-TIGFHTRVGDPVDAMIEYVSTSGVDLIVVGSSGKGMADRLILGSVSTGIVHKSPVPVLVTKP- -> -NDRKKVLLCVDGSENALRAVEFARDLLAPLDAYFTLLVVVTPMIGRAKSRAASSLLEEAGM-DHCLSALTGNPAEVILKLSG--KHSLVVMGRKGSGSLQSISLGGVAGQVSQNIKVPLLLVP-- -> -ESITALLVPVDGSEGSARGARYASELAELAGATVTLLHIIPAAAQRGPFAVACDAMGRELG-EVDHRIAYGEAASAIMRTAREVGADLIVLGSRGLTPEEDAWTRSLSRRLLSQATCPVLVIPN- -> -DMPEVLLVPVDGSKNASAAAAYAARMAEKLGVPVQLLFAFPETYSPGGFKLRDEAMGDSSV-SVEEKIITGEAAAAILDHSGSVKGGMIVMGRRGLSRVEEILMGSTTQRVLHHAKCPVLVVH-- -> -NVEGPILLATHGTENAVRAEDEAFELSRRLGLPVTALYVVHEN--ADWTRTFIRKGRGAGI-EVRRVIRIGEPGQAICDEAREMKAGLIVMGGRALKRSKEFKARIRMDRFLREAPCPVMVIP-- -> -PMYKKILFCADLYAGSDYAFAAALDLAERSDAELIVFHVLESRYAEKRI--------ENPE-FVRIEVRAGVPWMEIVRFARKEKVDLIVMGSYTIHDLEKPHLGENAQKVSLRAPCPVSIITS- -> -TVFRRLLVPVDFSACSLQAARHACAMTRMVGGSLILLHVLDGRA-------LLGNEARHPP-QLRVVSVASDVALTILDVAHSERADLLILGTHGRNDLGSGVLGQVAHRLVLAADLPVHLVPE- -> -MEISLILVPIDFSDCAANALSYGKKIASSWKAELLLIHVVDSVSSEDTFRHFLNDLGRDGL-IKDTIVSYGSPFQEIAIKARELQTDLILMGGYGSRGIDEIFFGGTVDKVVRLLPCPVLCVPM- -> -KRISAILVPTDYSNCTGEAISWAVALAAPLSADLLLLHVIRRED-EIMFRTWMTDEGEISL-LRETLVTVGEPVEKIVTTAFERQVDLIVIPTYGRKDPEEGI--SVSDRVVRMATCPVMTIQA- -> -KPYQQILVPVDFTKISNTIVARANELANFYQAKLTLLNVLEDAG-PAKLRKLADNLGAANV-ALEVTYASGKPSDAIIEFVKQNGIELVVVGNSGKKS-VLGFMGSTAEATLKGVPCDVMAVRI- -> --MLQKVLVPLDESSFAEQAIPFAQRLLAPEGKLIIMTVVEENNHATEYLKQLGAVLRKDTTHQVEAEIRVGAPSVCIVEAAQDYEVDAIVMSTRGQSDFNRLLIGSVTQKVLNDAQCPVVVVPA- -> --MTQSILVPLDGSRSARRALEHACLMQQARGGALHLLHIVEPPHGMALLKETWAAVGDPDVHFHVEDNPQGRPDRTIVEMAQTLEVEAIVMGSRGLSDMKGLMVGSVSHKVSHVAHCTVITLHV- -> ----KTILFASDFSNLTDRAQSYALDLARATGA-VTLIHSVEPIDARSKSQSVVAAFEEAEI-ACDVRVEVGKRWKAIVDAASSGDYDLVVLGSHKINDGDKVYLGTTTHKVFFATEVPLLVVP-- -> ----PHNLLATDGSESAQRAAEVAAHLAQVLRG-LSIVTVEGGIFATRVLCQARDIATKTGT-AVEARTSWGDPAEVILEMASRGNVDAIVVGRRGRGRLACAFCLAVVRRSW------------- -> ------------------------MRHAAYYAQRVSLFHVELPIMSAAALLPAEEVLRAAGL-AFDSQHVVGDPADQIAAAVQRLQPDLLIMGTHGHSALKGFVMGSVTTKVIAATSVPVLLVR-- -> --MLQHILVTTDGTALCNSALDQARELALRLDCHLTILHVIPDLACQNIIQSALQRAAGTQA-D----GIVRTIAQVIVEEADALNVDLIVMSTHCRTGISRLLTGSVAETVLHHARQPVLLTHEP -> --MYRHLTVALDGSHNARPALIEAVRLAAAAKARLSLVHVISV-QGQFILDEGREYAQQHGV-GVSAHLLEADAATVLVDFAAGAASDLLILGTHGHRGWKHLLLGSFAEAVLRRTTLPLLVVRNP -> --MNSRILVSLDSSAASLRGLDEAIGLAARDGSALRLVHVVNASAGEQVLQQGRECAQAAGI-AAGTLPFTAHVADIDAEQAGAWGAGLIVAGAQGNCRFGRALQ--------SRTSIPAPLVRAG -> --NYKNILVALDDSEITDLVLQEVLKFKEHQNSNIRLIHIIDATEGQKLLDRAKEICHHMKI-NVDQKVVEGRIAEAIVKEAQEWPADLLVMGTHGRRGFSHLLLGSVAENTIRLATMPMLLVPAH -> --MYNRVLVPIDGSETSMAALREAIRIGQCQQVGTQIRLLYVI-YGQDILDQAKQEIESAGL-RVETRLVEDRIPQVIADEAKAMPAELLVMGTHGRRGLNYLLLGSVAEGVMRLTLCPVLLVRSS -> --MYTHIVVTTEGSHIDHAAVRHAAGLTRALGARLTLLHIVPDAEGERALAEGTVDAACSRL-S----AVQRSVARAIIEECAALGGDLLVMATHGRSGWQRLMQGSVAEDVVHHAHMPVLLVHQG -> --MFRRLLVPVDGTPVALEAVDAAIAIARIGKADIHLLHVIPSFRALAWLGEAREHALGAGV-A----CEGPRIHEAIVDVARDYGCDLIVMAAPLRSGMVSGLFTREAQAVMQASAIPVLAWR-- -> ---MIKILVPVDGTECALNALRHAAFLAREGGRSEVVLLNVQAPLGESALATACELEAGV-----STLIGLGHTARTIVSAAEDNSCDSIVMGASLWSQIKAAVGGGLPAQVIRRASVPVTVVK-- -> ---PEGILVPVDFSKHSEAALIFAMNIAELMERQVIVLHIVHEPAAEMMEKFIEEATC--D-FKAETKFLDGIPSRRIVEYAKKIDAHMVVMGSHGHRGLKSVLIASKARKVMQYAPMPVTVVK-- -> ---NEKILVGWDGSEKSRNALRYAIDEAKDKGLKITAVHVEKGESRSKIGSLLKEAIG--GMKEARVIKHGYGPAVDIVKFAEKNSFKHIIIGSHGRSGISRIALGSVARGIVEKAHCIVTVVR-- -> ---KEKILVGWDGSDQSRNALRYAIDEAKEKGLEIAAVYVEKEESEVKINKLLEEAIG--GLTETHLLKNAHGPAVDIVKFAEKNDFKHIIVGSHGRSGISRIALGSVAEKIVEKGHCIVTVVR-- -> ---FKKYYAQQIFSAESKEAIRYAVKMGNQSQTVIHLIHTLEAPIMNNLLAELREKGY--GV-----VKDNADSAESIVEFAKSIEAEAIIMSSHGRRGIKRLLMGSVTESVMRLSDIPVVIIR-- -> ---KKIFLVAVGFSEKPEDVLEKAVEVARKYKAKVYTIHVIAEMPMDLLKRYIGKMDY--E-----PIIEVGDPGIKILEKAEELDVDLIIMGHHVRTGLTHILHQNSCERVVRHSKKPVLMFN-- -> ---TPSIVVACDGSEHSLHAARMAAELAQATGQTLKLLAVFPGTKEEEAKSYGREVAAKKNGMPAEEVLLKGDPAKEIIEYMENNPGTHLFLGRRGHSLVRSLTLGSISEKVVRHASGPVTVVS-- -> ---ARSILVAMDDSPLGRRALAYALET--FPDAHLVAAHVAYLE-AQRVFEAIKE-----DG-AVTVSFLTGEPEERLVEYVDSAGFDGVVMGTHGRDGVARLFIGSVAEAVVRKTDVPTTLVK-- -> ---FEHVLVPVDGSEAARRAAEHAIDLVSDTGGRVTALYVIDM--RKKGEELTAEILA--GVDETAV--VTGIADEAIVAYAEDNDVDLIAMGKHGKRDPDKPLVGNTARRVVQESSVPVHTV--- -> ---MDKILCAIDGSKAAQRAVDFGVALAKKNKADLRFVTVSTVSQEALIEKELSEAHA--DLQASCVTIRGRDVATAIVGYALQEGFDHIVMGSTGHTAFGRLLTGSVVDDILKTQHPPVTVV--- -> ---TRRVLVPVDEFLQAKKSLAYILSE--HPCAEVTVLHVIDSAEVTSLITDVQR-----GV-RLSTTTKIGRPSQTIVDYAEQHHIDQIVIDGHGHSSTDYVSPESVAETVDCRSPVLVTII--- -> ---APHVLVPYDDPELAAAALEHALTE--FSTGEITVLHVFEPADDDSILSRARK-----DR-TLLTARTAGDRPNAVHEYAAEHDIDHIVVGGREQDGESQFLEQQLADDVASGSPVPVTIV--- -> ---VTQVLVPSDGSDCAARGVERALER--FPDAQVTVLRVVAPVDPGGAVAR--C-----EV-DVRTVVEPGVPASTIVEYARANDVDAIVMGSNDRSSLGRLLLGTVSGTVAENAPVPVELVT-- -> ----MEVLVPINSRDSARETVEYALRE--YPDASITVIHVTPRNGTDQLFEMANG-----GR-LLTTITAVGCPVREIVAYAEKSDTDHIVIGNCKRTGLARFLFDNVTKGVVYRSPVSVTVVK-- -> ---PQHVLVPLDGSDRSFAGLEYSLASF--PDATLTALFVVDPTRGERVLDRAVDREVGR-----RTLLRTGTPHTEILAAASESNIDHLVLGSHGESPITRPFLGHVSDCLLYTSLSGL------ -> ----MDVLVPVDDSDCSFRALGFGADMAARYDADLHVVHFADEESTDAVVERAQRVARDASTNIDVDVRSGGRAGSEILDLVDERGYDHVVMGHHGAGTIERAILGSAAETVLRSEKVPVTVIP-- -> ----MDVLVPIDGSDGSFRALVFAAEFVRKFDATLHVVHFSDEATTDEILSRARDVSADISTD-RLEFRPAERVGENVLELVTENGYEHVIMSHHGSGTVDRAILGSAAEKIVRSEAVPVTIVP-- -> ---MKKVLVAVDGSAPSEKALEYALEDSKKLDSQLTILRVVISLPEEYLEELKDKA----GGVANTKVLTGSNAAAEIVRFAKEEDYNEIVVGGRGKLGLRPSP---------------------- -> ---------------------MEGIELAKKIGAEVVCVYVAKENAAEQFMQPLRESAEAGNV-KFTSETFISTTAGYIVYAAEKNGCDLIYMASRGYTGWENFFMGGVASKVLAASQIPVLVYKV- -> --MFSHLLVPVDGTGLSWRGVLVSLELARKLEARVTGFVVMPPLHAREILADFAAEAAKAGV-SFEGRAERTSVDGAIVEAVEKYGCDLIVMVTQGRGSFGEMLFGSHTKNVMARCTTPLLVLR-- -> --MFKHIFVPVDGSELSVRAMDASLELALKLGARVTGFVCEPDIHAHAVLDSFAQRARECGV-PFESEYRRSQTDATIAEVADLVQADLILMVTHGRGLFGEMLFGSHTKNVMSRTKVAMLVLH-- -> --MYRRILVALDGGAAAEASLEQAILIAQASDAEVEVIFVLDISAAEGVLAAAAT--KRARV-RFTTCLIQQGIAETIAAEADAWSADLIAMGNNGNHGPSGPRMGEIVRKVMARTRQPLLLARA- -> -SLYHRIIVPMDDSLAAHAGLRAAIDLAQDQQAALKIIAVVDEAGARQLLQEAEQ--RAAGL-SPESELPDGHVARHIGAAATAWQADLIVLGTHGRHGFSRWLLGSTTENLLRGLAIALHIVPC- -> --MFTRVMVGIDGSRAAVAALAEAIRLAAAEKAAIRAVSVVER-VAQAALARAHD--LLTGL-TGETALGESDVASVLLRESHAWGADLMVLGTHARHGIERVLLGSTAGPFLRMSTIPVLLIPH- -> -LEIKRILFPIDFTENSSKILPYVLSVSEKYDGMIYLLHVVEDLGAEKRMDKVCDEQL-KSCPNFQRMIVSGDPAQEILKTIESEGIDLVVIGTHGRKGLEHVFFGSVAENVVKKSPVPVLTINPY -> -PSFKNILYCTMIGPNSPYIFKHALALAELSGGKIHIIHVMEALEAKERLIALCPPKN-GD-MIASISIVAGKPTEQILKKSDEVNADVIVMGATSTHSLFEKVVGYTAQNIVSNSKVPVLTVQVP -> -IEIKKILFPLDLTENSSKILPYVLSISEKYNSTIYLLHVVQDLSAKKAMDIICEKQL-QSCPNFQKSVVSGDAVNEILEIIESENIDLLIMGTHGRKGLEHVIFGSVAENVVKKSPVPVLLINPY -> -PEVKKILFPLEFAKISPAVVPWVEFYAQQFNAELHVLHVVPYSKAEQSVGHFINEHF-AK-SSVVTKCVSGDPANEIVKYAEAQGIDLIIVGTHGKHGLDRSLYGSVVDLVLRYAKMPVLCFNPA -> -VSIKKIAFCTDFSENANQAFDLAFDLTRKYQAQLLLVHVVPPLRAKEQMESNYLQKI-GD--NALVRVLSGHPASEILNFVEQEKVNLVVMGTHGFTGLAHFFLGSTAEKVVRRANCSVLTVHKA -> -PEIKKILVPLDFSGNSIMLIKKASKVAKELGAELEIVHVVESLYAEKKMESFLAENL-SD-PHQAKIITGNDAAAEIIRHAEENNCDLIIIATQGFKGLPKFLFGSVAERVLKQAHCPVMTVKPR -> -IEIKTIAIPVDFSEATPIIVEWGKALAKKLGAQIILINVIEEIGAREYMQSLLNKHF-SD-PNVKPIIVKGKIVEKIIEVAKENKADLIVMGTHGKKGLDKIIFGSVAEGIVKYSPIPVVTINPY -> -PSIKNILVPVDVMEDNGFFVEYAKMMAEKHEAKVTLLYARPPLRAIDELDKLAENQL-QN-TDVSIKLRRGQPQDLILEMTETGDYDMVIMGTHCRKGMERVLFGSVANRVVKHSNTPVLTIHPA -> -VVFKHILFPTDFGTGCTREAAFAFSIGQEHDATLTLLRVVRHL-VKRQLRDLVPSGA-EA-CETNFRLAAGDPAGEILHFVEKTKADLMVMSK-GADWLAGHVPGTTAYKVVSKAHSPVLTVRS- -> -NKTMKILVALQFTESPDEILDRALSVAKKYEAEIYTIHVIEEMETLKEMTSYIGKLS-DQ-KKIEPIIVVGSACDKILETAEKIGADLIIIGHHVRKGVTHMIHNNIAEKIIRNAEIPVLTFNIR -> ----MKIAVAIDGSDHSIRAAEYALTLLENTDGELEVISVTDYNYQDRLVRPVVEMAEEAGV-KTTVKLLRGKPDVEIIKHLQTEEVEQLVLGSRGMNLMQEMALGSVSRSVMEQANCPVTIVK-- -> ----MKIAVAIDGSEHAFRAAKYALTLLKDADAELEVISVTDYNYQDRIVRPVVELADKVGV-KTSITLLRGKPDLEIIKYLQTANVEQLVLGSRGMNIMQEVVLGSVSRSVMEQANCPVTIVK-- -> --AFQKILVALDC-LEAATVFQEALKLAKT-GSKLMLFHCISWEKVRHSLQAYRDQAISQGV-SVEYKYQVGNPSGSICEQAEDWGADLVMIGRRNRFKWSELFSRRVSSYVLNNASCSVFMIQT- -> --MLKKIMVAIDE-AASEWAFDLALEMAKA-NAELTLIHVLDVYRYEALLKKYQGKAKSAGV-SAQYKQPYGHPGPTLVKTVKEDGIDLMVVGNHDPSTTESSVLGSVSNYLVHHSPCSVTVVHP- -> --NFKRILVAINH-PLTSIVFDRALNLAQQ-QANLMILHCLVDFQAKVWLEEYCHQATARNI-STEYQHHFGEPGATISSIAQEWNADLIVLGRHDHSAIAEFFVGSVSNHVVDYANCSVLVIKD- -> --SFQKIVLAIDD-KFSEYILKQGLEIAKI-QAELMLFRCIPHNTLE-KLKYRCEQATNHEL-NISYRYKIGEPGYSICETAQEWSASMIIIGRKGHSALVEALIGSVSNYVIHHAQCAVLVIEP- -> --SYQKILAAIDLSAGKSSIFKKALTLAQQ-QAQLVLLHCSPLPLARQQLQDLRQQATAVNI-EAIPLLRFIDPSRGICDAVKDLGVDLVVVGRRGLSGISEILMGSVSSYVVHHVSCDVLIVQA- -> --MLKKILVAIGDSAESQAILDAGLTLTEK-GAQMLILHVINPAMGIERLQAYAAQVKERGI-EVEVSQNFGDSGRMICELAKNWSAEVIVMGRNQKSMLSEIFLGSTSNYVLHHAPCSVMVIQL- -> -FSLKKILVPTDGQAHSVRACQYAVTLAKLTRAEIIGIHVMPSQEGAEHLKQIEKMCVRENV-RHHTLLLEGYPPEEILKTAQKENASLIVLGIRKRSRFERHF-GVTTSDKIINANCPVTIINTP -> --MSFTYLVPYDASNNAKRALEWAINHGKLSGAHIRVVNIQPSFLFGECTEGVKALLDASGL-QTSMEMGIGDPKEVIVDLVKDDPIDLIVMGSRGTNPMFSGVLGSVSYAIINSGICPVTIIPQ- -> --MNNLLVVPIDGSPSSMKALAFAIDNAKMYQDKIILLNVQAKYKGLEVMKEAINMLNGNNI-PFEVKIRIGIATIEITSEAKEQEARMIILGSRGNGPVVSAVLGSVTYGVLHLATCPVTIVPL- -> --MQNIFLVPVDGSEQCLTAVDHAVEAALVSGYAIQLLNVQPRITSDRILYQAEARTK-GRV-EVVCKTRWGIPAEEICEEARGIAVKGIFLAPRKPN----KKLGSVTYKVLQKSTVPVTVIPV- -> ---MHKILVAIDGSEHSERAVRYLIGLIQDGGGHLVVQPLLPTRKSAEDSQKAEVLLKQEGI-AFALHTLQGDAASQIVACSRSLGCDSIILGSHGNGFLAGIFLGSVAAKVIQLSDLPITLVK-- -> --MLKRILVPIDGTEHSWRALEYACELVSYTRGSLVIMTVVSGRMGDEVLDAAHAILSGKNI-DCTYLLENDNIAKSILRAVGEQECDGIVLGSRGMGVLEGLFRNSVSSVIAENANVPVTIVK-- -> --APKSILVPVDFSERSLAGFKAAKHLARRFHSKVTLLFVDEWTANRELLRRYDENTRAAHP-GTTTKVIEGGAKEELRRLTREGLFDCVVMGTHGHGGLWRFLLGSVAHSTLYASEIPVLTVHAA -> --MYDRLLFPSDGSEITSSVFKYTLEVASEHDAEVHIVNVADSTKGEQIVLETAKQAEGREI-SIVSNVLQGQPHELIVEYGEQFDIDLIVMPNHGKEDLERFLLGGVTERVINHSDIPILTVNPS -> --MYEHILLPYDGSEGAAEILHHASEIAHWTNATIQLLYVADTTKGQTVVEKAAKTLDTLGV-TYNTDVVQGNPAVTIAEYAKRYDQNLIMMPTHAREGISRHLIGSVCEKVVRLSSVPVLTARMQ -> --MYSTILLPVNGSGGSDELVNRTLNFAQRVGASVHVLHVVAAQRGRDAIARIHDHATALDI-ETTRVVREGVPHQVILDYAAEHGVELIVMGRHGRTGVEQVGLGSTTERVVALADAPVVAVPVT -> -----------MGGGPANAALRLAIRLTST-NTTLHVLVVEPETETDRILDAVREEVAEWGR-SARTVVRSGTPRDRILEYAADHDIELIVMGAHGHQSVKRVDLGRVTEAVVHAATVPVLVVRAS -> -NIYEKIVIGFDGSASSRLALQKACELGERFGSELNVVLVIEPLAANMIIEKAKKIAANYKIKNVNYMVKYGVPANEIMKTATDIKADLIVVGRKSKKGLEKVLLGSVSQSIVNLSKIDVLITPY- -> ----MKILIPVDGSKMTKNVIDKAEEIGKVFEAKLILMTVLDSALENML-EKLKEENSDYPY-EIETVLKTGMPYDEIVKLADEEDVDLIVMGNRGLGAFSRTLLGSVSNKVLNHSDSVLVVKTD- -> --AVKKIVCTVDFADHSSLVASYAKEFAQKFDAEVLVLYVAPALGAEANMKKFVAANF-SGV-KASGRVATGYVSDKILEIVDEVKADMIIMGTHGRSGLAGFILGSVAEKIVKLSKVPVLTVHPQ -> --TFSKILLPIDFTECSTAVLSHAKLMKEKFDADIYLLYAMPGSEAENAMENFINQHM-QGE-PKKAVVRIGEVVTETATYVDEEGIDLIITASHGCRTAENRIYGSIAEGISRESGCPVMIVHP- -> --PPQRILVPVDVKEPMDESLFMASALTLEEKGNVELYNVITLTPIHT-LKDLTLPY--FET-KFDVAVGEGQVANEICRRAEQIAADFIIIPTHGRKGLTRFLMGSVAEQVIRYATCSVLSFCP- -> --GQGPIVFPTDFSAASLAGLPWAKRLTRFMETQLHIYAAVEPQGAETRLQAVAAHLDGLDL-PVIPRILVGNPADEIIQYADEVAAAMIVIGAHGYSGVRHLILGSTTESTLQHAQCPVLCVKA- -> --MFKKILYAVDIECGCYAALPYIMKLKASGTEEVILVHIYDERVTYKKLKEVESKLRTTGF-DTKIIVDTGTPCKKIVEIAKKENVSLLFLEHKKKRG----IVGRTTMTVLDNIECPVFIVKE- -> -PEIKKILYATDFSEEASHAFGFAATLAHHCKAKIVILHVIEELVAIQSRLEETQYPDTPFV-VEKIIVKTGHAVDQIIRHSEGDKCDLVVMGSRGQGVLADVTMGSTSRRVLRRCSKPVMIVRI- -> -MKFQRILIGIDESRYSENAAEYGFALARTYHAQVGLVHITEPVL-SGKLIENTIKRFGDDL-QITQFNEFGSTADTILECIAKFNADLVVLGTHSRTGLDRFFMGSVAEDVVRHSPVAVLVVPL- -> -MKISKILIGIDDSTYAHNAAAYGFDIAHTYKAAVGLVHIIEPAM-SSSLIDNIKKEYAGEL-EVTSFTDFNITADGILSCAKQFNADLIVLGTHSRTGLDRFLMGSVAENVVRHSTIPVLVVPF- -> -KKVNSILCAIDLSQHSAQVLEQCFRFVNQLGAERLVLHTCHSECKLEKLIQKQ---DPIQA-DISIRVIEGDPVDTILKTVETTETDLVILGTGGKTGINRFLLGSVAENVTRKSTTPVLIVRA- -> --SLKHVVVAFDGTDDSKEALELGIRMSKKMDSNLSVIYIHKENHIMALENEAKQILDRHHV-QADVAVSYGEPSEGIVTYAKENNGDLIVVGSRDMSGLKKLIFGSVSEKVSQRASIPVLIAK-- -> --TFHHIVVAYDGQDESSAALTKGIQLSKQLGTRLTVVHVYQAEHSDEVSSRIRMKLDENQA-TGDVEILSGSPADAILSFADEHAADLIIMGNSDSGGLKKLLFGGVSDKVHHQSNISVLIAK-- -> -MQVKRIMVCLDGSKNSLRGFDAAISFAKQSNATLVGIHSVTKFEVRGIIGTVEKKAEKSGI-SFEPVVIGTAAGTDLTTFAPKNKIDHIVIGSRGLSFPKEIFFGSTSTFILHKAKAPVTIVK-- -> -NRFKRILVALDGSANSRRGMNEAISLARQSESTITGIYVLPGGKAKKFMSNTKTSAARHGI-DFEEKILTSKDTVEIANFAKSGKFDIIVIGARGAGSPKSEFFGSVSNGILHSSRIPILVVK-- -> -MEIKKILVTFDGSKHSEKGLDIAISLVKESKRSIVGLFVKPHSIVRKTFQTLREKCEENDV-KFSTEIRTGDVKTTIEKMTDHMNIDMVIIGSRGRGSVKGALLGSVSKYVLDKSKIPVLIVK-- -> -SLIKHILVPFDLSDMSHRAFEFSLDLAKKYNARISVLTIMYSEQISTSFILLEDAAKKFSV-QLKSDVFSKNVADTILSFSTNRKVDLIVMGTRARSSPRRFMIGSVAMDVIQKASCPVILVK-- -> -PIFRKILIPFDDSKLSEKAFWYAVNLDMNHKTEILILSVFHSDNVKLKHNELKKVAEKYNI-ACNSYTISSSISESIISYIYSTRSDLVIMGTRGNSTGRKLMLGSVSLEISQHSPVPVLLVK-- -> -LNISRILVGIDGSEYSIRALEFSKNLAHKYNSQIIAFTAFNIPELKILLSNLTKKAIEEGI-NLKVFDTKLTPDLAMTEYAESEGVNHIVIGYRGRS-FENLLIGNIATSIVKISKCSVTIIK-- -> -RKIKKIVIPYDGSIYSKHAFDMALNLAQKYNSKLILLTCIEKIKILKETSKLELISKKKKI-STTTKFVTDSIVEQILSFTKSTKADMIVMGSHGRSGIDKLILGSIANGVVQRSKIPVLVVR-- -> --------MPYDGSNYSNNAFQAALAIAIKFESKITIATCLFRPNAITELAKLQKIAVTKKI-SIEARMSCNSVVDTLTTFANANKVDLIVMGTRGRTGFKPLLLGSVSVGVSQYASCPILLVK-- -> -DEISRVVIPVDRSESSRIAVEQGSHLAKLLGVDVAIISVDASHEHENILDEYKKIVEQKEI-TTHAEIIVGDAAEEIIRYA--EDNDLIVMASHSKKGMERFLLGSVFEKVLQKVNCHVMVLKP- -> --MIERILVGTEGSQAADNAVSTALRLARAADAEIRAVHARETPEGERVLEAVTERAGKVDV-PATTVIDDRPPAELLLAQAREWGADLLAIGAQGESGFERAIRGSVADQLIRGSPVPVLTVHQP -> --PKRAILVATDFSKPGKLVVPYAFKFALALNLRLTILHVVKVPPGKLELGRIVRFANENGL-MADHKLLVGIPQDTILEVAHSPDVAFIAMGTHGKTGLDRLRLGSVAESTVRQAPCPVLTIGAS -> --LFKHIVVGTDFSQQADVAVQEAVYLARQHEAKLSILHVIDERAVARTLFETFGEDSLNSV-DIKTIAMFGRPQYELSSYCQSNDVDLVVAGRRGDSPLKQVLLGSTAEKLMRQSPIPTLLVAHP -> --NFTKIVCPTDFSKSSEYAMWYAHAFAKGMNASIHCVNVFDNGALKKKLDHVIKKAHLLGL-EADGEVRTGRPALEIVKVVEESDANLVVLATHGHTGLERVLFGSTCERIIRLSPVPVLSIKHP -> --MIERILMPLDGSAASAHTLPYGLALASACHAELTLLHVVVDPMA-KWAGAALLAAQAAGI--GVR----NDDRPARAILAAAAAHDLTVLGSHSRLGLDRFFLGSATQEVLRRAEGPCLVVRLP -> --SIRQILVGTDFSEPSINAVLHADALAQLCQANLTALFAQVLHDDRERFAALKS---EYQV-DFESRVERDVSRNALLRTAESVDADLIIVGTHGRTGMGRLALGSVAEGVVRDAPVSVLSVHYT -> --MYDRITIAIDGSDEAKYAAKRGLELALTLNATVDALYVVPQKSLRAFLSEIEELASEIDY-PIVTALSEGKPAVQISKHASDQNTNLIIIGRQGITGLGKRFLGGVSEQVLYQSDVPVFVIPDT -> --MFKNILVPLDGSALGEKALNVAIVIAKAFDAKITLLHNISITSFADYLKKVEGRLHDCGV-AQIEQVV-QGIPTSAIQLAARNGVDLIVMTTHARTGIARTILGSVADEVVHSVNIPVLLIAAQ -> --MDGTILLPVDPDTDSTAATDCAIASARQTDATIRVLSVLEFHDLTAAVDAAAERIENAGI-PVVRDRCEGVPYQEIVSLAAQTDPGLIVMGTRGSTTADEPRVGSTTQRVLALSAVPVLAVPLD -> ----MRALCATDLSAASEATIENETCLDCLGRIGVRTIHLVTVVPGERGLDRYRAVIEAAGF-DVETHVVRGTPHRRLNEVARTVHADLAVVGSRGRSPLENRVVGSTARNLARTTVVPLLVNRVE -> -QQYHRILVAIDGSYEAELAFRKAVEVAKRNHGELYLIHVVDTRTAKQTMEQYVETAKKLGLENVEYSIEYGAPKVIIAHDMEQHDIDLIMIGATGLNAVERLLIGSVTEFVTRNAICDVLVVRTD -> -KKYTNVLVGIDGSEQSEMAFNKAVTITTQNDATLSLLSVINGEEMKKKLATYKQTAMDAGVKDVNIDVKIGNAKVELGSDYRDNDIDLIVVGATGLNFIGRMLVGSTAAYVIKEAPCDVIVVKTD -> -QQYKTIMVAVDGSSEAELAFKKAVNVAQRNEAKLLIAHVIDTRMAKQTLDDYATYAKEQECHNIKTVIEYGAPKPIIAKQLQEHEVDLIMLGATGLNAVERLFIGSVSEYVIRNAPCDVLVVRTD -> -DNYQRILVGLDGSTIAQQAFEEAVAVAKRNRAALFIASIVPDNEAEKRVHEATRYAEEHGVTKVVPIVRVADPRRALAETLVDYHIDLIMLGITGKGVIQRLLVGSVAQYVSRHATTNVMLVKQR -> -AMYNKILVPVDGSHNANLALDHALTLAEKFDSEVMIISAIDTRSAKRHVEAAADVAKQRGI-KYTTLVVKGDPKTLIANDLDEYDIDLIVMGKSGVDAITRITIGSTTAYVARHATHNLLIISDD -> -FPPKDIMVPLDGSKNAERALTTAIALAKENKARLHLVRVIDPNATENYLEDVAKRVKESGFTNFSTKLLQGNIKSTLARSYEEHKIDLIMIGATGMNAISQAVMGSITAYVVRHATVNVFVVKDE -> -TIYRRILVGVDGSNEAEEALKRGIQIAKK-GATLGIGFVADVRYGKGLVEIYKNEAEQLGVENVETFVKFGTPKTTFVKKIDKFEPDLVLVGSTGLTPTEQFILGSVSDYVAAHAPCDVIIVRGK -> -ADYKNILVCVYGEESSEDTFDQACAFALKEGAKLYITSVVDPKQASEQLQAFKQKAEEKGIAEVETILDVGTPKVRIASHIPNYNIDLIIAGETVGRRVERAITGSISKGIAKRATCDVIIVNDS -> -EKYRKILVGVDGSSQSKQALKRAIQVAKDFHAELLIASVQNDAQLVLFLNQCEQLASEQGV-QVDAVMAHGSAKKELAVTIEKYQTDLIVVGATGLNRVEQMIIGSTASYIIEHTQTDVLIVRTE -> --MIKKIMVAYDGSYEANQAMNIAVNIAKGVSAEIFLVTIFNPFDRKKLNKKAE----DQGI-KVQSKVIEDRIGPNLVNFALL-DIDLIIMGRRSIGAINRLVLGSVSNYVIQAAKCAVMFVKE- -> -KHYKTILVGLDGSANSLSALEKAGELARSMDAKLVLVTVVDPKQAQKMLAHYQVKL-PEKV-KYQAVVVIGDPKEMLSEILKKYQAELVIVGATGLNKLDRFILGSTAAYVVRNTKTDTLVVNE- -> -SNYQHVLIPVDNSEPAEVAFNEAVNIAARHQAKLTILYVVDDRHAAAAMRDRRTFVETTTVPALQTEVAYGDPKRTIIDYAQHPEIDLIVLGATGKDSPHRVAVGSTTSYVVDQAPCNVIVIR-- -> -----------MVQNLLRPPFLKACGAAKRNGAHLVITTIIDTLNAEKMLEDYEKQAKDMGVESVETILDYGPPKATIVEIAEKFHADLIVVGAVGTSRLSRILLGSVAGYVTLHAECDVLVERES -> -QLYKNILVGIDEGPLSQKALHQAIQLAKQNQSTLYVVTVLSEERAEKLLHEAKEAFTNEGV-TGDCYLQFGSAKKLLAETLETWDIDLTVIGAPDKHLENYFGIGSVASYVVRHSKNNVFITKQ- -> ---MVKVVVAVDNSSSAERAFKRAVEVMGG-RGSLVVLHVTEVVTATKFE-GLCHSASPKVAQWEYREVEASSPKEALLRQTELEGADLLVVGRKGMSTLDKLLLGSTSEYVVAHAHMPVMVVH-- -> -AGYERILVAIDGSDQAEIAFQEAINLAK-IGASVALASVIDSREMEAVLSKYVEKA-AAGFESIGTYLEVGNPKKMLSEELDLFGADLIICGATGLNRMEKMLMGSISSYIVQHAKCNVLIARES -> -ENYKHVLLAYDGSVDAEKALFKAVNLARRNNAKLTVAYVVDVREHGKEMKLKMKKIEEYGFDNYHLRIEKGNPKTVITYDLDEVGADIVICGSNGIDSYDQMIMGSTSENIVRYSSVDVLVIK-- -> -ETYKHILMCYDGSKNAEKALMKAVNVAKRNEAKLSVVHIIHKDQHAEEIRRHVEVMDRADFKAFEVLIDTGNPKTKITYDYDDLGTDLVICGHTGMDSYDKMDMGSTSENIARYSSVDVMIVK-- -> --MFKHILVPLDGSDISKHIFEQAVEIGEHFGIEQMTLLYVYEESAKERLN-ALKEGNSDSF-KINVEVVTGDPRNLISKQYEDDGIDLIVMGATGKGNLERLLLGSVAQYVAKHAEVDTFLVR-- -> --MYKNIIIAMDGSENAKKALDRAVVLAK-MKAKLYIVNIIDTRVFSKSLMDSYNEA-LADIEDVNIIVEAGSPRTMITHEIRRVNADLIICGASGLSKTARFLLGSVSENIVRTAECDVLVIRHQ -> -MQQATYLVAVDGSKNAERAFQAAVDLATVTGAQLTLLYVINDRAEHELLNTYQKTA-QQQHINVQQAMVYGYPKEQIVTYSDNQPTDLIFLGATGNNAFEDGELGATASYVIRHAAANIFLVK-- -> -KPYSRILIGLDGSDQADRAFNIACVLAQVLSASLYVVWIVNRDQISAKLNPYVKKAADQHI-DVTGKALIGNIKTLLAKDVDEYKIDLIVLGNTGSNMVGKMLQGSHSGYVIQHSGCDVLIVK-- -> -SIKRKILVAVDDSDQARDAFVEAVTIAKAKEANLYLVSVIDEDQRQELLNNYRQAKNQFDFDQVNAEVFVGEPKRQIIHLLEDPAFELIVVGATGKNARERLFMGSVSQFVVRHSPVSVLIVR-- -> -ERYYNILAAVDGSPQAHQALMEAVEAARRNNARLYIAQVVNSSEKEAAIKLLEEEFAGIDYYNKQMVTCVGSPKKVLCFDLETYKIDLIYMGATGKGAVERMLVGSTTAYVVNNAPCNVMVVK-- -> -SNYKNILVGIDGSEESEKAFLKAKEIAKNNEAELVIAWINTELSR--YVSVKEAEAKNDGVKKVISVVMTGEPKKYLSKVIQKFNSDLIILGATSTNIVRNILIGSTAKYVVKNSKCSVLIVK-- -> --MTAVYLVALDGSQQADKVVRKAVAEAQRSRARLILFRVLETPTRDALA---QQELKQYPELEVSYYLQEGKPTRCIQQFADV-PVDRIIMGITGES--EQNLTGSTTAYIVNHAPCDVLVVK-- -> --MHEKIMVATMGEY-MDEIMKYTLDIIQERKTEVIGIYVVETSQGEEILESMRQEFQHYMI-NFKKLLREGDPAEEIVKAAEEEGVDLIILGT-GKDIIDKRLLGSVSEKVVHSAPCNIMLIKT- -> --MYSKVLVPIMGNY-TKELVDSTLDLIGDREVEIIGLYVVDDSKGKIFLEEFEQLLDNKNI-SIIKKLSKGKPAEVIVKAAEDNCVDVIVMGT-GKSIVDKHLLGSVSEEVVHFAPCTIHLVRT- -> --MNKKILVALDDSDYAKNVMNQALELARSYQAELLGVSVIDTLSYQALIDE---CVKKSNV-NYIHEILEGNPSEEILKHAEKNNVEIIVMGSLGKTAAAGIAIGSVTQTISALSKCSVFIVK-- -> --RNWRILVPVDGTKEALSAVHLAGELALVMESPLDLLYVSPFDEAQEIFAVAEPLL-PAHV-AHVCHHRTGMPTDEILHFIDEMGIRLVVIGGRKHSRVTGLLLGSVTQAVLEYAHSNVLVAGS- -> --DHARILVPVDGSEGALRAARIAGEIARVTDGTVCFLYVALFDESQAIFAAAAAVL-PEGV-SHAAYRRAGAAAEEILRFIDETGCDLVALGGRRSSRVSGILLGSVTQAVLERAQTRVLIAGQ- -> --NIQQIVVPINGTAESFKALSLASDLAKIYQAQICLLLVTYFSYAESVFLRAKDLL-PANI-DISTHHLSGQPASKILEFTKAHNTDLIIMGCRKLNLFSSILNGSTSRQILEKSTCPVIIVK-- -> ----MAILCAVDGTQPHESVVSTADDLARAYDDELIVLHVMTKDMAR---EAAADVL-DSTD-RVVARGRVGDPTAEILEVADRVSARYLVLGGRKRSPVGKALFGSTTQSILLEATTPVVTVMD- -> ----LKVLVPSDGSSNSLYAIRHVIDEFNKGGLEIHLLNVQPPFQADAALIETRRMLDAAGI-PYTVHSEVGNKVDCIVDAARRLHCDLIVMSTARKSSLVRLIENSVTNQVLEKASVPVEVIPGE -> ----IRILLPLDGGEHALDAVRHVIGMRQAGEIEAVLLNVQDPPAGEHALAPAAALLQTADI-AFETVVVTGDAAHEIAEQALLLGCEQIVMTTLSHGALLGRLQDAVSHEVVRRARVPVTLVPPP -> ----MKILLPVDGSALSLHETRFALRLVQEGKAEFVLANVQEPAAGADSMAASAKLLESFNV-PYETAVLTGDPVPAILELIESYGCDMVVMGSRALGLVRTALEGSTSSKLVQDSPVPVLLVKPP -> ----IKILIPVDGSQQSMHAAYHAMRLVSGGKARFVVVNVQEAPAGHDLVRPAVALLSASSQ-LVEQVVASGDPAHTLLELVESHECDAVIMSAHGGGNDVERGLGSVALHMAQHCPVAITIVRPA -> ----MKILLPFDGSPLALEAVKWVIRLCGEGSTSVVLANVQEHAAGAHTLQAAQTLLQEAGL-AYESEVATGDPAHTLVDILENYGCDLVVMGASGASVLRSAFLGSVANELLHAAAVPVMIVKAA -> ----HNVLVAYDGSQPSKRALQYVIEQARDSPMQIHVINQHGAVEADKVLKEAAATLAAAEV-AHKTHAAMGNVAEQVNAAIKQLGCDTVVMGTRGLGSFSGLMLGSVANRVIHEVSVPVILIK-- -> ---MRKMLLPIDSKTVPEKVISYLKDFVPEMNYEVTLLNVISADPSKEMLAGFEEKLRAAGIDAITTMTVTGDPAESIVKIAESGGFHMIMMCTHGMGAAKRLLIGSVTNKVVHHSSVPVFVIRE- -> ----MKILLPFDGSDSSYKALGYVKEFVAGMEYEILLVTVQKTTVHLNLLSDALKYLNGFSHSRIRTYVGFGHAADIILEMSELENLDIIIMCTHGMGAARRFTLGSVTDKVVHHSATPILILR-- -> ---MRKLLVPIDSNTLPDSLKKLLEDFVAVMDYEVTLIYVTPISLAKNMLSEVEAELKAVGIERIQKVHVMGDPAEEILKFAEAGEFHSIAMNSRGMSAVKRLLIGSVTNKIVHHATIPVIVVK-- -> ---MKKILLPKYGSMKMDDLISAAENLAKKFNSTVTVFHVFNCPEFQKELDDTVKLLKDKGIR-VDSKLFKGDPATDIINEAESGNYDIVIMSTQGIPSGQRLLPGSVTGMVMNHIDIPVLVIR-- -> ----MKILVAIDDDSLCQTVIDFVAKVFSHHATIVKLLHVVQPSQASAFLNTLRDLRSKPSE-PVEVSVLMGTPHRVILDCAEEFGADLIVIGSHGHGELSRLKINSVSYAVLSHADCAVTIVKA- -> ----MKVIIAVDESTYGKKIIETIAHRKWQPDTAFRIISVVEPVNATKLCLELKKSLELPDC-TVHYDVLEGSPRKEIIKAAVDWMADKILIGAHGHDLCDRFVWGGVSRAVAVAAPCSVEIVRP- -> ----KSILVAVDGSENSRRAVEHVAAVLVCSCEMVTLLHVIAEPEAETYLEEYKILTGAPSS-RVTVEMDCPSIAQCILAQRESLGADIIVLGRQGRGAREELLLGSVSKRVVHHAKCAIWIVT-- -> ----MKVLIAVEESECSRLALESVVKRHWPEGSQFRVISVVEPM-KRQLVKDDVELLKASED-SVSGDVLSGDVRHCILDESKEWGADLIVLGSHARKGFSKLFLGSVAEGVAGNADCSVEIVKG- -> ----MRILIAYDGSPDSEVAVDEVVARPWPKGSPVRLVTVIETPEGYQRIQKALAKFR-EDL-ETSYELKDGSPKSSLLEAIRDWAADLVVVGSHGSTRLERLFLGSVSHALVTHAPCSVEVVRS- -> -------MVGLDGSNYSNWALFEAISLAKKFNGSIKVISVYKQDEREASKIQHKNLIEKIDC--SFLAILGSNPSLALVETARNENFDLIVVGSRGLSDAASFLMGSVSRKVVSKADCNVLVVKK- -> -------LIGVDGSEHSKKALAEAIKIAEKFGAEVTVVSVFYPATPSAHDFSHRAVLEYEKV--KLISVTSANPSKVITDMARDGKFDLVVIGRRGVGAAHELVLGSVCNRVSCESPVNVLIVM-- -> -MTYQKILVALDRTDASDRVFDHALGMARSSQGQLQLVHSINVSETQQWLEQLRTEALNRNI-AADFVCKMADPGPFICQLAETWNADMIVMGNSGKKGLKKLVLGSVSDYVAKHAPCPTTVVPN- -> -NMFNQILVSIDDSDMTQHVVDEAVSLAKATNGSLMFLHAISLYGKKNWLSSLCESAAYSGV-KAEFTLNVGEASKMICDMARSWNADIIVIGRRGHRGLTELFLGSVSNYVIHHAPCSVLTVQR- -> --SYRRLLLATDGEATTRRATAAALSLAAAYGADVDALSVVDERSLDASARETAMEGASVGL-SVAPRVETGVPAARILD-VADAGTDLVVVGARRPTDAETRPLGSVSRRVVRGSPVPVLVVRGE -> --GFKNVLAPVDGSEASRDALQYAVDFAKASGANLHILYVCESLSYEEQMKEALEDFDFGDF-TYEAHFKVGKPAFEIVNAADSLETDLVIMGTVGRSGIAGLFIGNTAERVSRSLSCSILTVRPS -> --RFRRLLVTTDFSEGTPDALAHAFSVAQENESQVTLLHVIHDVGVRKQLEDLVPTEARNWC-DIVTRVETGVPYRIILRTLEDEKIDLLVMNIHGKGMLDRALLGSTAERVVRAASCPVMLIPPM -> --ALRHLLIALDGGPCGEAAVTQGLALARALRARVTLLHALEPA-AAALLAH-AGREAAG-V-TA-VALVEEEAGAA--ILTAERRADLTVMGACGLTARGPLGLGSVTERVLRASATPHLVVNRS -> --KISSIVVPIDLADDNETALNCALDLAGMTGAGVTAVYALRLDELRERTEEIDSSGAAVKG-GIKTDIHGLSPAISVANYASRNNADLIVINTHARTGLKRLVLGSVTERMIQESPCSVLSLRP- -> --DIKKILVPLDISDTADSSLTYALGLAGKLGASVTVVYVFWIDELRLRVDAVYRDKGAPEA-GIETRLTGVSPALTVTDYADENGFDLIAITTHGRRGLERIILGSETEKIIREARCPVLALKP- -> --DYSRLLVTTDGSENADTATRHAAAVADRYDALVHVLNVVDIQRLEANGRDAADELRTASV-ETAVTTSLDGVAAGIQEYVSDNDIDFVVMASHGRSNLKRQLLGSVTSQLLRTVDVPVLVTPRS -> --VPSSMVIAYDFSGPSKRAAEVARAIHGVCHGPLHLVHSYLDVALRLGLEEMAEEFSIDAQ-AIQTHLVTGDPADGILKIAERVGATLICAGTTGKSGIERLLIGSVARRLLHDSPVPLLLAHDS -> --SIQRLLCPVNYTPVAMKALQSAVVVAQCFEAGLAVMHVLEAE-ALAHLCEWVPEDVRLRC-QVKEMIRRGDAAKQIIEVARELESDLIVLGAQHKRFFDTTVIGTTTVRVTRHAPCPVLVVPSA -> --AIHRVLVLVDDSDASRHAVDVCMELASILGSHVYALLVLSPLRAERLLEG-RAQKSAG-V-ASTEYTFDRRPDTVVTARACTHRCDLVVLPRHGHAPHHTL-FHDLTELCAMAAETPVLVCPQP -> --DFHHVLVPVDGSAHSREVLAKVAPFLAEG-AKVSVLRATGLT-YVAHLKEQLGHLEGHGL-NLEPQVIDGEAADSIVHFAEQNGCDLIAMSTHGRTGFRRFILGSTTEKVARQAACPVLAFPTH -> --DIDGVCLATDGSTGSAAATEHALAIADACDATLHALYAVEPDAFEKHGEKTAERAEEHGL-DTVEAVEHGVPTDIVLEYAERDDVDLVVMGTESKSDVERLVVGSVSQRVVPNASVPVMTARTL -> --LFRRVLFATDFSEHAARAFDAFSYLRHATE-AATLVHVRSPK-PAERLAERARTLEEWGI-ETRTEVRRGDPAEEILDVEAATSPSTVLVGSKGRSRIRRLLLGSVSGEIVARADGNVFLVPPP -> --DLSTLLVAFDGSKHASEAAAKACTLALRYGSTYLLSTIYEMSKAAKLQEPIVAMLRERGV-RFERLVEHGDPVFQGLELARKKDAGLAVLGSRGTGSLARVLLGSVAARFISTGVCPTLVVK-- -> --SFKRILAGTDTSEYGNKAVKKAGMIAKSYKGDLAVLSVIKLPDLEAHLVSLTEDISKEEV-KVEIFVKFGEPYKVVVETAKEWGATAIVIGAYSSENQK--SLGSIGEKIIANSFCPVLIVK-- -> -TQPKQIICAIDFSPLSDEVLIYAAGLQ-RCGAELTLLYVETEIKHLHAFSHYSEILAQSGG-LARFSVGYGDPATEILACAERLNADLLVLGSHGSTAFTRLLMGNTAETVMRRACCPVVIYKSP -> -RTLKKIICAVDFSACSDAMISYAAEMG-CKETELIILHIASENMHLHEFSRYSNILEPHGS-NIRFALQHGDPAAGILGYAAEQQADMIMLGSHGSTALTRLLVGSTAEMVMRQAECPVMVMKTP -> --LGQRILFCTDFSENANFAFNFAVEAAARPGSQLYLLHVVPESEARHDINEYRSRL-PEDL-ELKVEFRVGKDYQEILNFTHENQIDLIVMGRQGHNALQKAFFGNVTEKVVRKADSAVLMVPL- -> --LFSKILFCTDFSRESVAAFSYALELCRTKDAEIILFHVIPEPDAKEAIDQYLSRV-PAGT-RVSTRVAVGNAGQQVISLVEKEKIDLIVMGRKRKK-SPGVFFGDSAKATLQKAGCPILVIPE- -> --SMKHVLVPIDFSKNSEIAMNMALEYFGDKTSSITMLSVYEGSESALIEMTFEEKA-KTKKAVIDSEICKGNPSKVIIDTAKGKRSDLVIMGSQGRGSLKSMFFGGTTYQVSRKAPCSVMVIRQ- -> --MFKTILIALDGSPVSFRALEMGMEMAKKFDSKIVATSIVNVDQNNQILRTAERQLVNSKM-FYEIVSREGDPKSLIAVIPDNINADLIIMGKTGKGMMTKIFMGSVARYVSENSELPVLLVN-- -> --MFENILIALDGSKNSYDALNEALILAKKFNTKLYVVSVVNIADAQIILNNSQRIIESHKI-DYEMDLLSGEPRDELIDFANRKQIGLVILGKSGVHALERFFVGSVTRYISEHFNGNVLIVS-- -> --MFKKIIIAVDGSPVSYRALDYGIELAKRFDSLIELVAVVNTNQVKKHVKVAEQQIKNAEL-SYNVILEKGDPRGLIADVPKHTGADTIVMGKTGRHAIKNFLIGSVTHHVIEKAQIAVLLVD-- -> --MFQKILVPVDLSETHQNTVRIAAQLAESTKGSGTLLHVVETMRARAHLEKLRATAQ-ANA-NWRVEVLFGKPASEVMRFAADNAIDLIVLTSHRINENLGEGWGTLSYKIGILSQCPVLLVK-- -> --MFTHLLVPVSRTEAVGRALEVALALAQPAQSRVTLLHVVERLQAARDLETAGERFRGAGV-ALYTKVLLGTRVETLVQYTHEHDVDLVVMQSHPVDADPARGWNTISYKVALLAPCPVLLVK-- -> --MYDKILIPVDLSSTNEAVFSTVRDLGDPDRTDIILLHVIETLEADAKMKDWAAMIAEDGF-EVQAAITYGERGPEITRAADENEVDLIVQRSHKVSEDAETAVGTVSHQVAIFAPCSVLLVR-- -> --MYKNILVPTDLTDKNEPAIREALSMAFQSGGQLHLLHVLEKLQADETLTRWQQHFQSEGV-PIEKLIAVGKRAPEIIHYCREVKIDLIVMAARIIKEQQ--SFGTLSHQVALFAPVSVLMVR-- -> --MFKNILVPSDLTERNHKAMDIAVEMALENRAVVTLLHVIETVRAGRKIDKLIAEYGREGL-LMEKHILYGGRVYQIVNFAVAHGVDLIIMRSHKLDENVTEGWGTISFKVGVLSHCPVMLVK-- -> --MFRQVLVPLDFTPKNEAAVAVARSVTAVD-GTLTLLHVIERIRSGERMTAMLAGLADAPF-ATRSRIVYGRRAQAIVEVARDLGCDLIVMSSHQIADRPASDWISISHKVAILAPCPILLVK-- -> --MYHRIVVPVDSAGHSKNALIHAIKLAKQTGSKPIAIYINPIINALDILKDIMVDIGHPPD-AIDRRAATGDPTTLIIKMAAEERADLIIMDNKLFGRLAGF--RGISNSVIKYATCPVLVVK-- -> -INYERILVAIDGSKGAEIALDTAIDVTKRNDAHLDILRVLDLNENEQYLSELRDKLIK--FEQINVHIRFGNPKLVIEDFQPEYNIDMIIVGSTGKSFLHRLITGSVAAHVIRTAKCDVLVARST -> -GTYERILAPIDGSDISEQVANKAASIAHRDSAHLDLLYVIDTNDSQTRLEGYRDQVLE--DLDIDIHMRFGSPKKVITEFPQDHDNDLTVIGKSGLSRLERLIVGSVASFVVQNSKTDVMIVQN- -> -KRSNLILVAVDGSEQSYKAVQEANKIACPE-DRLILLMVKDMR--RSLLEAARLVN-P-----FTTKELTGNTKRKLVDFAREEKADLIVMGATGADFFEHLLLGSATHYVIDHAPCDVLIVRCI -> -APYRRILVALDGSTESDTALNIGIETAQKH-T-LALCHIVDDHKGMDIIAHGRTQA-E--LHDVRIFIQEGSPKEVIEVIAKTFVTDLLIAGASGMGHDQSFILGSVSEHTSRTASCDVLLVRNH -> -TNYQRLLVAIDWTSASEKALELSTMYTREN-LQLDILHVIDSSKNMHKLEGVLARA-LSSEYQTHIHLRFGDPRKVISDFPEEYRNDLIVLGTTQKNRIQRALVGSVSSHVIKTAKCDVLSVR-- -> -MTKDRILVAFDGSAAGVAALEKAVAITDVA-ASIDLLYVIDTRRAEIELEEQAK----ARGIEVRTHLRFGNPRTVVLDAPKDYASSLIILGRSSKRLTSRMFIGSVASFVTENAPCDVLIVANP -> -MAYNNILIAVDGSEMSNLLIKKVHEFV--PEAHIDILIVVDT-DAEKVINKAYD-YAK--HANTDVHVRFGAPKQVIRDFPRDHKNDLIVVGETGLSRLQRAMAGTIPSFVTHTATTDVLIMRTA -> ----------MDGTRATPGVVDKAIQLAIVNHAHLDILNVAQINIVAQRLKDIKTRA-L--VKSASIHVRFGNPKTVIRDFIRDHHNDLIVMGSSSLNRFERALIGSVTAYVIRLAPCDVIVVKQK -> -RSWHRILCAVDLSEASRATVTTAADLAHRTGAELALVHVHEPLRLGAELQRWRGVAQGMGR-PVRALLASGGAAGEILRELGEGGYDLVVIGAHPHRRLGRTVGGAVAARVVREAPCQVLVAHQ- -> --MSRKILVAVDLDAPFAIAIEHAQRFAAVMGDRLALLHVVERGTLIEAAEGWRERLNETIA-PGQLRLRGGSINEQIGAEIEEQGFELLILGGESRHTLALFFDGGGTARLARHAPCDVLVVAR- -> --VLNTILVAVDDSPTAKFVIKALGQLRLQPTTNVIFSHIVPTVGADEFYGHLEKQLRAFDC-QTEIEIVAGDPAEEIIRLANIYKADLIIIGNRGLTGVKRILERSVSSQVVSEANCSVLVVKEI -> --KFKKVLIAVDFSEITRDVVGVGCHFAREYGAQVDFVHVVEEGDLESIEEEIEAIARK-LT-RIETTIVEGHPATTIVEEAHERHADAIFVGSHGWSGIKSFLMGSVASKVLKNARCSVMIIRPE -> --LRKQILVAIDGSPLSDKAAEEAVRMAATPPYRSKIYAMLVLPVV-ES-DEWQELRRIEEV-PLETKIVYGDPADELMKFADKEKVDVIVIGSSGKGFLKRKLMGSVSSKVAAYARCSVYIVRG- -> --MLKTILVDVEPDPLAGQVMQTLRQLRLEPSTTVILAHVIVATGLESFHDRIEKQLHSLPC-QSQIEIVTGEPVEEIIRLANIYKADLILIGSRGLTGMQRILLGSVSSQIVTDAPCSVLVVKPK -> ----MKLLLPTDGSTYSRNAAKVAGRIATKHNAEIVIVHVVEDKTWET---GAEQVISSLAS-KLHAEIVDGNAPEKIVKTARLHSVDRIIIGTRGQTGIKKI-MGSVTQKVLQMSDILVLVVPPD -> --AVEQIVAPVDFSDLTEVALRHVAQIAPLYDVPVTLVHVVEDPYARAAEQRAEEALQSLE---VSYLVHRGQTTSTVVEAT-GHRDTLTVMGTKGLSGLRRVMLGSVTEAVIRASDGPVLAVPA- -> --GDGTMLVPVDFSEHRPRLLAHAREIAPVYGMDVTILHVVEGRYPGTLAERAEKALAEDA---VSIAVRSGPPADQVLTVAEETGAAFITIATHGRTGLERMLTGSVAEAVIRQAPCSVCTVKS- -> ----MQILLPVDLSQPTEALVHTTAALAHRFNAEVDLLHVMDPERIPP-------------A-TIRFHVVQGQPSREILKFARSHHTDLIVLASPALSRTKYFPASSLTEHIASAAPCPVLVLRM- -> --PARRILVPVDLQEGTASLLAFARHLAREVGAKVDLLHVLEPLWVPTVRERATEALRAA----PGVYVERGSPASVIGRVADVLDSELILVAPRQQGRVAKALLGSVAGGVVRAAARPVLVARS- -> ---LSDIVAPIDFSKPSYQAYAHARYLAAAFGARLHLVFVAESRSPSEIVDNSRAALQHMG---HKIHIEKGEPAAAVLDLIERKGIGLAVIATRGHSALERLLLGSTTRRLLRMASCPVLTLRT- -> --TLEHIAFGTDFDKSSLMAKTQFISSLEASQAKGYLLHVFDAS-SQTIQDSVQEQLDREK---VEAALLEGPAWEEITEFSEEKGCDLVILGTHHYQGINRMLLGSVAEKTMRLCHRPVLVVPN- -> --KVEKIVCPVDYTPACADALLRAAALAPQAD--IVLVRSVDRFG---------PRLRAWV---LK-LMTANASASEIVAFAKDLDADLIALGLAGDRSLV---------KIIQHSTCPVLTVSG- -> --QPEIVVVCIDPNTPIQKILDAAIDRTGPGAREIVLVSVTGGPDARLVLERAETHCRSRGV-TPRLVVREGGPADEIVTLAAEVGASLVVVGSRGRKGVLKTLLGNVSAEVVERAPCSVLVVR-- -> --IFRLIVVPVDSSPNSMRAAEVALNMCKEFGSQLVVVSVVDTGDAEHTLEMVEEMAEGYDI-SIKKVKRKGHPHLEIVTLANELKASLIIMGKGGRRGGSRLALGNITERVIEDADCSVMLVW-- -> --SYKHILALTDFSEYSKKAIEEAANIARCQGSKLTVLHVAHDQEIEDKFNKLEDDVALKDI-DWESNIRRGTPYIESLYEIESGDYDIVVLGSHGDGGFKRIVHGSTAGKILRHCPISVLITKI- -> ----RRVLIGYDHTQVSNAAMEWIVAIFPEDD---CIIVNDD--KSKDALE-VVQWFSTKGF-KQPV--LNGDPAETLKDYAEVNKVDLVIVGSRGLGFFKRQLIGSVSDYLTHHLKCSILVVKED -> ----HLVLAAIDDSSAAPLIVDFLTSHKWTEG----LIHVIAP-YAEKLLLK-KSDMQQKLA-QEITDVVGGMPAEVIVDEAKRLSADMIVVGSHGRTGFTKFFLGSVSGAVVSHAPCNVMIVRVP -> ----KKILAAIDGSVHTQKVLDTTIALAKAFD---EICHAIC-DNGKKIIE-ARKLENNGIK-DSIM--DIANAANMILERIKSENFDLVVLGSRGLNEFEGFLMGSVSDKISHHAKCSVFIVR-- -> ----KRIIACAVDPTSAGYVINWILMNLI-------LMHVRP-ASHR-FLKACATQFWHNGI-DKAS--MMGDPKEELMRKVKDVKADVLIMGARGLGALKRAFLGSVSDHCVHHASCAVVIVKHP -> ----ARLIVGVDESPAARWALAWAIGAARLHR----AVHVSR--RCTEVITSFED-VAGGVE-DRTVVGRVGDPGYHLVDLARE--GDLLVLGRGRRGLLSRIFLPSTSMYCARHARTTVVIVQQP -> ----RKIVVAIDESPCCDNALTWCVKNILR--NDALILMNVQPTLLIEAVGKARK-----LP-DKIAISLKGDPREVLLEEIEILDANCVVMGSRGLGKLKGTVMGSVSTYLLHHVRCCPVICVKP -> ----GCVVVSVDGNEGSMDALRWALDNIKLRPGHFLILYVQPPAITDAILNHALQICAEK---KNVTQVVIGDPKEKICEVIENVHADLLVMGSRAFGPIKRRLVELFH----------------- -> ----RKVVVALDPSEEASYTIDWIVDNFLIPK----HLISAL-EKTNDAMQPFAKKLETANI-KEVLIKSNADSRNIVVDYTEKEKADVLIMGSRDLSVWKRLFLGSFSDFCQHNAHCPVLIVKGP -> ----IDILISLDPSEYSKYTFEWVLQNIIDPQ----HVLTVQ-EKAEAMLKAVLKEAFDGKL-EEML--ASGDARREIVEYSYKASADLVILGSRGHGAVKRVFVGSTSDYCVHNCNCSVLIVKKP -> ----RKIVIALDPSEEASYTVDWIIDNFLMSE----HLISAL-EKTSDAMQPFAKKLEAANI-KKVIISSNNDSRNIVVDYTEKEKADVLIMGSRDLSTWKSLFLGSFSDFCHHNAHCPVLIVKGP -> ----RKIVAAVDDSEVSAYAFTWGLQNLVRPD----AITVAP-ASSKALISKYLKQCANANI-SEGV--VKGEPGSWIVDEANRVRADMVLVGSHAYGLIKRTFLGSVSDYLAHHSPCPLVVVKST -> ----LNT-----VLDLSLYAIQWSKTNFLRVG----VLWVLPDCANTKMKQV-KEDFEQLG---EPLYVESGDARGFIPLYADKLNADTVVMGNRGNSGFRKMLLGSVSDHCVHECKCPVLIVRRK -> ----RSVLLAIDKSKEAAYAVDWALENLIRPD----LLYVAKSASGLDFLDE-ENKLRQNE--AEVRMVRNGDARAEIVAAAEEMNASMLIMGSRGATLLKKALIGSVSDYCTVNAPCPVTVVKPK -> ----MKVVAAVDASEESLHALSWALDNVVRPH----LVVV-H--FA----YPHGTACPVQQS-STHY-VRSRSLTELVCVCIRRQAYSTSRPRRRGLGMIKRALLGSVSDYLAHHASCPVLIVKPP -> ------VVVAMDGSNLSTQALHWVLENLVFRKSDEIVLFHTQQEAAVEVLESGKTLCEEH---KKVTIVKSGDPRDHICEIVEKEQANVLVMGNNGHGTLKRLLLGSTSDHCVHRVKCHVIIAK-- -> ----KTYLFAADGSEPSKRALTYLLGM-TR------SVHVVT-EYV----LQ----CEAN-I-DEHE-RHSDAPAKELCAVAESGTYHMMVMGSRGLGKIKSKLLGSVSDYCVRHASIPVCIVRAP -> ------------------KALQWTVDHLYREG-----ITLSL--AAETTLKTYGKLLTSKKI-PTCL--AQGDPRTQLCQFVNDKQCAMLVVGSRGMGAIKRALIGSVSDYCVHHSDIPVIVVKED -> ---MKRIVVAVDGSESSLRAVSHALKLRKLSSVHITALYIGPSCRANEVFKKIDKIAGGKSS-SIEKAIGRGDAAAAISKFAMEGGFDLIIIGFHGYEEESKSYLGGVCYKVLHMCQCPVTVVK-- -> ----MKILVAVDGSPFTKRMLAYLAAHDEWLQQSYVVVTAVPAVEAEKVFKPIRTFFSKQKI-RAEFVAKVGSPADVIATLAKKGDFDLLMLGSHGHNSLGNLVMGSVSTKVLANCTTPVLLIR-- -> ----MKILAAVDGSPFTRRMLAYLAAHDEWMQHEYTMLTVVTAVTAEKIFKPLRTFTGKQGL-QASYVAKVGHAAEVISEAARKGKYDLVVMGSHGHGTLTNLVMGSVATKVLANCSTPVLLIR-- -> ----LKLLLAVDGSRYTRRMLTYIVSNELLFFYDHVLFNVQPGEANNALLEEPTQFLQAHGF-TPLCVTRQGEPAKELVVAAKQFQSNLLVIGCRGQSAIESMVLGSVTAAVLAHSHVPVLVVR-- -> -NMYKHILVCFDDSDGSRKALEIAADLYLLNQCQLSVVQVINGTDDPDLRAEVTEILQSRGI-SFHFDTLYGKTSDNICEYANSNQIDLIVVGQSEEGIFKRIFLGSTEENIIKNTTKDVLVVK-- -> -AMYKHILLAFDHTKSSEKALEAAVGLLALEKAELTITHVSTEKELDEALSSVKHNLDSRGI-QANFYPLSGSPAEAICEYATGNNVDLVIVGRTEKNNFQKWFLGSVSEKIMQESPCNVLVVK-- -> --MFNHVLVAFDGSDSSRKALSMGMSLCKDKDSLLSIIYVYNKTRLEEIEGYVRGIVNDSII-NSHFVVLEGSTDDAILQYAEKESANLIIVGNSSSSKLRSFFLGSVSEKIIKNANCPVLVAK-- -> --MFNRILLPTDGTDAMRTVIDHAVDIASRRDAVVHILYVVDDREGETALETTAELFHDSDI-KTTTALRKGDPADEIISYATEADIDLITMGTRRGEYT-ENLVGSVSQSIVARANIPVLTTNLA -> ---MKPILLATDGSEHAQQAAKQAIELAEEQGVPLYALCVVDKRHASMCVSKVADMAEKSNV-RVEGGIRHGIPHEVILEYAAEVDADAIVIGEHGD---HTEHFSGVGGKVAELADRDVIVVKAQ -> ---MKKVVVAVDGSDVSKEVIDYALHYAQREKAELLFLHVVNWYELGDWVQERVVSSGTPKPERMSINVLFGNPYNEIVSFAEKMDASMIMIGHRGLSNLERFFLGSVAAKVVAHSPCSVYVHRE- -> ---MKRVVVPIDGSETSKGVIDYAIYYANREEAEMLFLHVMTIHEFIKFIEERVRASGRGIP-RMSVSVRKGRVYEQIVRFAEEQDADMIMIGHRGLSPVQRFFLGSVAAKVVAQAPCSVYVHRP- -> ---FHTILVATGGSPWSNQAVTYAIEMAKDYTQ-LIILHVVAEPEGRRILAEASALATEAGV-TFSTELAWGRVPEVVCRVAQEHACDLIIVGSRALKGFKRLMIGSISNAIASKSPCPMLIVKW- -> --MYQRILVPVDGSHQSAVALEKAIQLAQQFQAELFIATVIDQRYAQHLLNQAQIKAKTNGV-LATTILAKGIPKKIIAHLPHQYNIDLVIIGKSQRDVLAKLLSSSTSNYVIRYGKSKVLVVN-- -> --PPERVLVPTDRSDAADRALSAGIDAAAATGATLHLLTVAETAAAEETLDDARTRAEAAGV-ELVTAVQQGQPYREIRSYIEDEDIDQVVLGTGEESDFGHFLWGGVTAKLVRSSPVPILIARNR -> --WPERILIPVKFTRHSDVALRCALSLAEAFRAKASLLHVLKNG---------ESLLGERMA-RLGWAIESGDPAATILKVAERDRFDLIVLAAHRKTFWKGFHLGMTAERVLLHSDVPVLSIPTD -> --PTRDVLVPIDSSQGADRALKEGINLANTTGATLHLLHVVEMALGNETITKGVEAANASVP-SVTSSIVYGRPHREIHSYIKANDIGLVTIGTHGQTDFSQYTLGRVSSNIVRTSPVPVLMVRQP -> --PYENILIPTDGSATATHAAEHVVDFAASLDATVHVLSVVDDRAATDAVDTVVSEAEARGV-TTVRHVEYGTPVEKIRDCIEANDIQPSGWGRWGGVARIVSCLAVSLKRLCARHQCPS------ -> --TVKNILYLTDLSKNASQVFRYALQLAKTFEGRITILHVLKNIEIIDGIKAFLRKLREDEGLVASIYVHEGDPVSEILDTADRIDCDILVMGDHSKGRLAYTFLGSTVEKVLRRSRRPVLVVPI- -> --QIKTIAYATGLGTGAPYVFRYALSLARQYDAKIEIVCGMAPLRVKG-IEAMCRSIIDDGKYVGTINVIEATPDQAVLQCAQRVGADVIVMGTHRRTMDQGALLGSCAVKVLHKSTIPVFLVRI- -> --MFSNILVAVDGSESAAQAFATALQFASDTGARLHPLFVIDLP------MKHCVGMARVGPEIDDLVRPEEDVAHRIEVAAAKLEADVIVIGTHGRRGPGYAPLGSVAEQILRSTTRPVLAIPA- -> --PIKTLLYATDLSEGAIYALRYAVRMAEQLDGRLHVVHALRPLTARE-MRSFWDEDPQARDRIASIEIIEGQPAEVILTHASALGADMILMGSHEHG-LVHTFLGTVAMRVMRRAHIPTLIIPY- -> --RIKTILCPVSLTAASKIVLMAAFREAWAHDAKVHILHVIPSFETRA-LKDLRDHLQRYTEMIATINVIDGDPVIQILNMADALKPDMLVIGTHAKGFTEHTIMGRVATRVLKRIRVPCLVVPP- -> --DVKKILYASDLEQGSRPAFRRAVSLCGHYRSEITYLHVIEPLSLQR-VERFCESLEGIMPSQVTARVEEGTPWRVILKVADEIEADVIVMGVRHHSAMEKFLLGSTPNKVMYNSKRPVLIVPL- -> --FLDRIVYATELEPDDARVFRHAVGLARQFDAKLHVITVAKGRALHV-LDAFCTA--PDAGVIAELHVRDGDAAAQILALAGRVGAGMIVLGSHGHSPLGEMLIGSVAHTVLVRSRVPVLLVPI- -> --AYRRVMLTADMSEGGRNAVKTCAALDIARGARASILHVLDAPEASQ-V--------GEWSFRQDLRQVRSPPAEDILAAAREESGDLLVVGAHGRSGLARFFLGSVAEAVLCRADREVMAIPP- -> ----MKLLVCVDLSPETPILIKYAQQFAQQLSARMCLLHVTDSQEHQQ-MQQLQ-----DAL-SAIGLLVNGSVVTTILKEADKLAADMIIVGSHHKSLLVQLIEGSTSKSLINQANRPVLVVPV- -> --MFDSILLPIDLNHPES--WEKALPMARRLCGASGMLHILGIVKALQ--DAFIIRL---GDAHATAHVGHGHVPEHILSAAKELNADVIVMASEPPDELRNFLVGSNADKVVRHADRPVMVVR-- -> --KYKTILLAIDLSENSAYALRHAVAIGRCHNAKVHLLHVLPDVDVRDKVHEFAKSLLNEYALIDDIHVHHGTPS-------------------SGKGRISHAFLGTMAKRLLRKSVRPVLVEK-- -> --PFQKILFANDMSPQANKALPVALAFAEDGGARLVICRVNKGKAAIDWC-------------DPESIVEHGNPSEALVALADRTGSDLIVLGSRRSTFRLEYLERGVTPAVIAQAKCPVLSLSA- -> --TGAHVLLTLDGSSNSLLAAQEALSLGRTCTTRLTVISVVKKDRARQMVDEFCARCREENA-VCDPLVLTGKPAKLIKQTALERRVDMILIGGRGKSFMAKMLMGNVTEKVIGKAHCAVLVVTA- -> --TGAQVLLALDGSANSRLAAEEALSLGRKCRTRLTIMSVSKREAAQALVDEVSAKAREEGV-SCETLVQVGNPVELIVQAAKERNVDMILLGGKGKSSMAKMLMGHVTENVIGRAHCAVLVVTA- -> --WSRAVLLALDPQAEAAQRTDTAVAVAAECGLPLQVVAVAEV--------AALAVARARDL-PCQGSVRRGKVHEQIVAAADAAQADLIVMGRHSAALGGRAFLGGTAQKVIGLAERPVLVVIA- -> --WSRRVLVGLDPLQPDVATLALAADVANECALPLHLLCVIPG--------DALARVRDRCP-RADGECRVGRPHEQLIAAAGTHEADLVVIGRHHAHNLDRAWIGGVAQKVIGLAECPVLVHVN- -> --WQHEILASVGDTPLAQEIAKLAGGIAAACDLPLTIVGIAER--------LYVALASALAK-RVQGRVCDGDPAAQTNAVAREISADLVIIGRQRYHLLP-FMHTSIMQKIIGANEVPTLVVPS- -> --DYATVLLAVDDSDEARRAA--------EFGMALHVSVVIGEA-RIE---AFAARLD--PR-PDTVVVGPGTPQRALPELASRYLADLVVTGSGSSTRFERVLLGGVAQSVLRHVRSDVLIVR-- -> --WSHGVMAAIDTSMAAEHVATVAAAIAVQCNLPLTIISVIQH--------HTVAVAAAAGA-RVKSLILLGKPFEQVLETAKSLGTDLIVVGRHGESNVVRTPFGGTTQKIVGLSDRPVLVVRV- -> --WSQRVLVAAEPGPQGRQVFAIGVAVAAQFSLPLHLVSVVAT--------EMQALAGQGGV-DARGEVRCGKPFTEILAAASESRSDLIVMGSRDDGRIGRALVGGVAQKVMGLTEHPVLVLHC- -> ---PKRVLIATDGSEHSRLAMELIRHVREKIPLKVTAVHVMDTERRDHALSM---ARKILGD-SAECISVKGHPVSVIAEISA--RYDMVVLGSHGRSGIDHLLLGSVAERVARFSKSSTLIVRG- -> --MYQRILIALDARPVCRAAVKEGVALAAAHDAEAVFFHPLPPFQAGKALSAAQAEAEKAGV-ACIKVMGTESDAHAIADAARKRRCDLIVVATTGKNALLRLLTGSVVPGLITVSTVPVLVVKDG -> --MFKRLLVPLDGSKLAESALPVVSFLTQVFETSVVLVHVIEQNEAKKYLEEISCLPPDALV-EYHVHTTEQKVAKSIIDHVREFDSDLIVMCTHGGGGAHDLLFGSIAQQVMAFGATPVLVIRPS -> --MYQNIMVAYDGSDGSRLAFDQAIEFKKALPVKLTIIYVNEQYFSKHMHNSIHQQLEEKGI-QANVLALEGSASKTIPAFIEEQHVDLLIIGNSGKSGLQKFFVGSVSRKLIKEAPCSVLVVK-- -> --MYTNMAVAYDGSDGSRMALEKAIEFVKIMPAKLSVIYVNEDYYSKHLQESIQRQLDIHDT-RASVLALEGNATKTIVAFIEEQNIDLLIIGNSGKSGLQKFFIGSVSKKLIKDSSSSILVVK-- -> ---MKTILSALDFSPISKAVFSASLDLAKTYGAKLYLLHVIHNLAEEEELSGMQKQAAAQGV-DCEALLLQGDVARVIKDEISRLSVDTCVIGTHGHGIFYKALLGSTSESIIEHCGCPLMLIPA- -> ---MKTIVAAIDFSDTTTIVIDTAVQLAHALHAEIVLFHATPPSILQQHLDNLITQVQKQGL-TVRSHTTSAVQRNAICQALESLHPDFIVIGSHRHGSLYELLGPGICSRIVRRAPCPVVVVHS- -> ---MKKIIAAVDLSDITPKVIETASRLASLSGAKLYLIHAEIPERYFPELESIRKKLEREGL-NVENVLLNGDIGGLILKKASDIDADLIVIGARKHSFLHKLFFEELGINFISKCPCPVVVVPE- -> ---MK-LLFATDLNE-PRYITDAAQQLASRLDAELFVVHVYVPSAEQHDFDTFV--LERFER-PVRPALHSGDPARVILEDATRLDVDMILLGKPRHSAIERMLLGSVTNTVARESKQMVLLIPM- -> --MFETVLFPVDQRNNALEMANAVITFSENQASRLFLLSVGGFSSHRSLLQETQARVEAVGV-PCEVVDRQVSSAVEICSLATELNVDVIVVGLKSVNPDQDT--DSTALNVIQHAPCPVLVVP-- -> --MFKSILFPIELTREARTGIEITAEMVKIHNSKLTILSVVEPNQVAKLLEESKSFFASRGI-LAQTIEKSGIPAFTICDVADEINADLIIMSCRGLGLIDEEAVESVTNRVINLATCPVLVVS-- -> --MFETVLFPIEQRNQALEIVKKVISFAEEHASRLSFLSLVGVQSLVQLLQRTRTAVEHVGV-PCAVVERPACSALEICSLATELNVDVIVMGLQGLNPAQDM--DSTALKVIEHSACPVLVVP-- -> ------IVVAVDVNDASSTLMAQSIELAVKEGAELAVFHCLRQSHHAEAWLQGLCIAKGKGI---RTHVAVGNPGEDIVEYAGDWGADLIVLGRTNRGTLADLLLGSASNHVVHHAQCSVLLVHT- -> -MAMDKLLVAYDESEGGDRALAIAADLARVNPAHVDIVYVIPIPDGEDMVAQAQEKMGE-DLGRVDSLLTGANPATEIVKLVDQRSYDLLIVGNRGLSGLKE-YMGSVSHKVLHASKIPVLIAK-- -> -MALSKILVAYDGSQAGASALDLAADIAGTNPVKVDVVNVVAIPDAKELLGKAVDHLDEIGLNEVETMLNGTDPAIEISKLADQDSYDMVVIGSRGLGGIKG-YLGSVGHKLLSICSKPVLVAK-- -> -MRTRHILCPTDFSETASHALGYAVEMANLYAVDIRLLNVISLPYADEKMKKMVAEVRPSGL-LVHTNIRSGGVLAQILEEAEEREVGMIVIASHGHTGISHMLSPNVAEAVANQALCPVLVVK-- -> -MRTRQILCPTDFSETASHALSYAIEMANLYQVNIRLVHVMSKPYSEEKLTELVAQIEDDVL-SVTPVIRSGDIFANILEDSVENEVGMIVIASHGHTGLSHMLNPNVAEALANKAKCPVLVVK-- -> ----YRILVAIDLKPGTDRLLAEAQRYAKALDAIVDIIHVADPDLEHQQAQAVADQMRAAGI-RVDALTVQGPTLETIMEEARKFGADLLILGSHQHGALYRLWYGDIAIDAAKEAPCALLVVPI- -> ----KTIVALVDLSSLALEVLRQASSFARAFNCEVVVLHVVPKQSNYAKLLEMIDDLTRAGV-HATVRQMVDAGVDEVLTETSGLQAGLIILGAHPHSTLYHLLIGSMADDVLKNAHCPVLVVPE- -> ----KNILVAIDFNDAVGELLGYAEGLAEKFDAKVWVLHVAEPDEEHRNLQMYCDTFLNDTI-EKEALLIQGSTVEAVLEEAQKLESDLLIVGTHKHSFLHNLLQESVSLKLLKKVNIPLLAIPI- -> ----QTIIAAVDMSPVTAKVVGWAMAQARAFNAQLELLYVTTPEDEQRALAALKAQVAAQGL-KVSEHVFPGVPEDKILQEAHRLQADLIICGRHDHDFFYRLFVGSVGEELLKRSPCPILFVPA- -> ----RNILVAVDFNDALGELMGFAESIASKFGAKIWVVHVAAPDEEHRRLQKLSEAFIDNNI-ESEGLLIQGSTVETVIAEAEKLKADLLIVGTHKHSFFHNLLQESVSLELLKKGNIPLLAIPI- -> ----KNILIPVEFDTNTQKLIDTGSLLAEKFHSKIWLIHIAAPEKERKIIQEYSDALNKKSI-DSTALLVQGQTIETIMEKVDTLHIDLIITGNNKHGFIYKLFIESVSDEIIKKSKIPVLLVPL- -> ----NKVLAPIDFSSVTDEVIAQAIKLCKAFGSELVLMFVTPPHKPGDEIISYAETADAGGV-AVSIVVQQGPTVESILEISNAIDASWIVLGSHGHGALYDLLVGSTVEGVMSVSSIPTVIVPG- -> ----DNIMVAVDFNESIGELMVYAESLAQKFKAKVWVLHVADPEEEHRKLQEICKNFIGEDI-KAEALLIQGSTVETVLNEAKKLKIDLLIVGTHKHSFLHNLLQENVSMELLKKVEIPMLTIPI- -> ----MKLFVAVDFSDPTDLILRVAKRLAKSLDASVWVVHAAEPEEEHRRLQQYADQLREAGV-DAKAILVRGPTVQALLAMAEKQGADHIVVGSHGRGMVAEMLMGSISQGLIRAGRWPVTVVPV- -> ----MKLLVATDLSDSASTMIERAQAIAKTLSAEVWLVHVVEPDGEHRKLQALAEGMRNQGL-KVTALLVQGTTAEKILHEASKLAVDMIVIGTPGRGAVYQLLVENVVKEILQQSPYPVLVIPR- -> ----MKILAGIDFSEVSDQVVNKAAEYALAFDAKLWLVHVAAPNKEHAKLKEYADACEEMGV-RCIPLLIQGTTLDTILEVLNKLNVDLVVIGSHTNSSLYDFVVGSIKNELFHKAKLPVLLVPR- -> ----MHYLVAVDLTEPTQKIIDTLIKCVNKEKDRVWLLHVAEPEEDMCDLEAYEAQIKAQGI-RCQSRIIQGVTVDTVFKKVEKWEVDMLIIGSHGKGLLREVLLGSVSEEIVRRSTLPVLIVPV- -> ----VNILAAIDFSDATNRLVPAITQFSKAHDAKVWLIHVAEEEDEHKRLQELAKELRDQKI-DATALLIRGPAAETILQEAERLDTGAIIIGSHGHGALHDVLMGSTGSSVLRQSHCPVVVVPI- -> ----MKALIAIDLSPASWEVIEQAVKLNQSDDNQIWLLHIANPEQQHQTLQEFAERLRAMGT-ECTALQVQGAYADKILQEAEKLQAEIIVVGSHGKGLVKELIYGSTSNQLVRRAEIPILLVPT- -> ---IQQILVPVDFHQHTDDLAAFASGIANKLGATITFVHVVGHFNAKKKMAALIEQHKA-ASPGCGGTVIIGEVADIIVRYAMDNKIDMIVMATHGAQGIEKIMLGSVADRVLKRAACPILLFNPY -> ---RQHIIVPIDFKTHSDLQANFALHMARLLNAKTTFVHVLRPIHMRKKVDAFIKALDK-RGVICEGVVLSGSIAETVIAHVDEQKADLVVLSTHGAQGIEKVLLGSVADRVIKGVNCPCLVFNPY -> ---IKRILLPVVFSDNDNLAAGYARQIAMCAGSEVDLVHVTPHIVAEKLMDTFIEKALP-GVKVRKKTVLKGQPADEILNYARENSVNMIVLPTHTRKGPEAWFVGSVAERVTKKAHCPVLLVHPD -> ---ITKIVVPVDLEQHTQKLVDFAIYIAKKMGVHLSFIHVTEFYRAKEVMANLIADNKS-QYENISGIVYKGEVVETIVKFAEEEDAGLVIIGTHGAKGLEKILLGSVAERVLKAVHCPTMTMNPY -> ---IKRMLLPVVFSENDMLAADYARQIAMCAGSEVDLVHVTPQIVAEKLMDAFIEKSLS-GVNVRNKAVLKGQPAEEVLRYAKENNINMIVLPTHTRKGPEAWFVGSVAERITKRAHCPVLIVHPD -> -MIPTTVLVPTDGSKPAKAAEVMAAEIAAAMGVEIVVMNVIPMTSAQSVVDAAVKRVGTHHV-TVTGKLEAPSPAQAVVEAHKGGACSLIVMGNRGLGGFGSLALGSVSTQVLHTAHCPVLIVKAD -> -MAASRFIVATDGSEAAQAACRMAAEMAQALRRTVTVVSVVRMGKHEELLEKAADEVTDDSV-QVETKLQSSSPAEAILEARGKQGETHLFIGNRGRGGFAGLILGSVAQAVLHHADCPVTVVR-- -> -VPIKRILIAIDFSDASREAFYAGISLAATLNAETWVLHASEPIGVHRRLDELYAELEAVDR-RKVHLVVRTRAAQEILDTAKAKDVDLIVMGSSQDGGFDS-PMGSTAERVARRAHCSVFCVRA- -> -PFVKHILFATDFSEDASRAQEYAMHLADVCDAKLDVLHVIEAPHS-ESLGV-EGDLARRGTPARVRLLLGN-PSEHIRQAAREQDIDLVVLGAQGRTNVLYGLIGKTAERLIHEGPCPVLAVPG- -> -LEINDLLVARDFSSVSNRAVRYALDVAARTGATLHVLHAEVLHGPGHDIPRFRQ-ESVSAVAIKEVERRDVSAGPAILNYAAETGVDLIALGTHGRRGPSRILLGSVAEEVVRRSDQPVLTVRG- -> -LQIRNVLIPIDFSESSLHAIECALPLIKRLGADLHLVHVFAPDST--IPLIE--KYSIEFRRENIHALKGR-PFEEICRLARDRGIDLIVTSTRGNTGLKHLVLGSTAERIVRYSPCPVLIIRP- -> -SRQPRPSVSRRFSSQRFRPSDGAKFIAHRTGAGVHLIHVHDSG-------RF---HNLPNATARCHILTGH-AFEQICKLAGKIHADLIVMSTHGRTGWRRVLLGSTAERVVQHAPCPVLIARQ- -> ---------------MSAQGIETGKRLGESFGARVHLAHVFPPLDAV----AWKE--LST--GDNLHFREGAPVFDVISSLASEIPADLLVVPTHAFRGVKRFFLGSTAERLVQHSPCPILVDRR- -> --MYKCMLLPVDGSPPSERAAALGLALAKRLSATAVFVHVVEPHLDQEALEAREQKAGQAQQLTSTQPESRPGVAEALVDAGVAHGCDLVVMGTHGRTGLPRVLLGSVAERMARLAPTPLLLVRG- -> -SLYKNILLGLDGSPTSGRALMEVASFSA-PGSTIRIVHVIEDLDSVESLRAIFKDLRSQGTSLLELRDLGGDVAGAIKAEGDKHDIDLTVLGTHGRGGVRRLMLGSVAEHFVRISERPVLLVHF- -> -KKLRRILVPIDFSEESINTLRIAKLLGERLRAQLDLVHVIAPFPRAILPMV-KREQSVQPLPYSCTTRIGA-PAAEISKAARKIGADFVAIGTRGYTGLKYAFLGSTTTQLVRTAPCPVLVVRE- -> -MDIQKILVPTDFSACAQHALTKAVDLAERFDATLHVLHVVDELAKATQIRRINHDGESIEIDTAVSVHLSFDVAATIHDYIEENGIDLVVMGTHGHRNIERLMLGNVADKLVRHARCPVITVNE- -> -MKLSKIAVGIDFSEESDAAAHQALDLARHVGAELVLLHVGTVRASVQAFDAVEQRLRAQGVEISHA-VRDGFADTGLAEGATELGAELLVVGTHGRSGLKRFFLGSISERVARLSSGHVMVARV- -> -MTIENILIATDFSDASQSALKQALRFANTFGATVHILHVVDELARADALRAIVEDDAGVAVNTHVSMQLSFDVSATINEYASERDIDLIVIGSRGQTDRSAYALGRVASQVIEEAPCPVLAVAE- -> -EKMWKLLVPVDFCHGCTNAFNLALSLAKKQNSKIYLSHIISDPDYASDIHKFGEKKARGISEIDTLITKGY-AASEIVESAKKIEADLIVMATHARKILKHAFIGSIAEKVLRTSPCPVLTTKL- -> -MIYNKLLVPIDFGDCTAPSLHFARVLAA-PGAELALMHVIDEQDTEDYSK--GESLVEDG-FSVNRIVVQGTPKDALLDYAASWKPQVLVLGSHGRTGLRRLLLGSVTEKILRQAGLPVCVVKK- -> -MQINQILVPTDFSENAQHALDYAIGLAKQCSAKLHLLHTPVVPS--EAVTILDASIDDAG-IEHFAAIREGTVHEVIRDYAKEHDVDLVVVGTHGRTGVSKLMYGSVTERVIKTVHTPIIVVPP- -> -KSLSKIILASEFSSTCECAREHAQALALRSGAELHVVHVQVLHPDIKAVEAMAR-VSGLDGAVTQVVMRDISASPAILRYAAEQQADLIVMGTHSRKGMDRLFMGSVASEVIRRSEVPVLAIGP- -> -NRPQTLLVATDFSPSARAAEDAGVAWAKRFGSTLHWIHALEVPAEATIGA-TEARGTEEG-LDGTSHLGDVPAAYAIADRAEELGADLVVIGTHGHRGVRRVILGSVAEKAVKLAPCSVLTVKG- -> -FQPKFILCPTDFSGPATLALYYGKYLSAYFDARLVVLYADQFSV---DLATITREHI-GGSSEVEMVVAENQAVPAILLTAEEKKADMIVMGTHGRSGINRLMLGSITEKILHETDHPVLTVSE- -> --MYKNILLGVDTQLKNEKAIQEVCKLAGP-DSLVTIVNVISEQKRCEELEPTRRRLTDCDI-QFEELILKGSPKEKLVETANRGNYEIVVLSNRKAEKEKKFVLGSVSHKVAKRATIPVLIVK-- -> --MFKNILVPFDFGNSFKNVPEQLVKLTGENAYKIVIFNVISETEKKDEMKPFLKSLDDANL-KYDVKFTTGAATKEIVNEVENADYDVVVMSNKRSEIDIKHVLGHVTHKIAKRVNIPVLIIK-- -> ---MERILVPVDFSVYSQKALEAAAYIALQKKCEVKLLHVVQQVYVQRL--GFVDRLKSKGI-KSSGIIVQGKVSKEVLLHAADEEIDLIIVGKKGESDIEEVLFGSTTLKLIRKAAVPLLILKN- -> ---MKKILVPTDFSKLSEDALAFAIEVAQKYEATITLVTSLHYDFYKEQMNQLIARYNVSGV-SIDEYISDETLITILNEKITHEAYDLVIMGTSGSSGIDEFLEGSNTEKVVRKAACPVISISG- -> ---MKTIIVPCDFSAPSRAAYAFAMAMAERTGSQVVAVYVIYIPVLNEQFEEMKRAVAHSSV-HSKLSIVNGSVVFALLAEITHYQASLVIMGTTGTSATQENWIGSTTEKMVRHCRVPVISVHK- -> ---MKNILVPTDFTDCALNAVKFAADIAKKTNATLHLAHIYKRVISKTYIADLSKQDFMKGV-DIRSSLSSVYKLHDILVMEKYHNTDMIVMGSEGVSGIEEFFVGTNTQKFVQMANCPVIVIKD- -> ---MKNILFLTDFSDTANKAVDVAVQLTQKFGATLHVMHSLNTAQQDTNMSELVDQLKAVGV-SPITVMSQDDVMHDAAEYAEDQNIDLVLMGTHGAKGFREAFIGSNAQKMVRECATPVLTLSD- -> ---MKTILFPTDFSNEAAKALPVAAQLARLFNADLHLIHVLQRLMPGAAFDALKATPALNAL-RVHTHVLTAADPADLLDDPRFAAADLLVMASTGASGLKELLLGSTTEHLIRRATMPLLVLKN- -> ---MERILVLTDFSDIARSGLEEAVRLAEQLGQAELLLNTEETSQGKERLQELAMQYSSERV-RIIPFIQVGPVQETVDVFIHNHKVDLIVMGTSGENTFEEYFVGNHTEQVLRIANVPVITIKV- -> ---MNKILVPYDFSDVAKHALNFAAQIARKSAESVTLINIIEQPTPEANMEAIMADESMKDI-KLNYKIVLGNPFKELAAEIETQGVKLVVMGTSGASGAEEFFVGSNAERMVRYSKAPVITVDH- -> ---MTKVLVPFDFTEQAQNALDLTTHLSNKFNVEITVLHVIEVPSAKQQLKDLESQYASNNY-VLKTKIVLGNAFQNISSAIIDQNPDLVIMGSKGSSGMEEVLLGSNAEKIVRTSHCPVLTVKG- -> ---MKKILVPCDFSATAVEAFKFAQTLAAKSRGEIHVLHMIDTAVLDRYFRAMEEAYATPEI-PIRLIKKMGSLVSGVEQYAREQGVDIIVMGTQGHS---QFGVGSNTGKVVRHASVPVLTIRK- -> ---RLNIMVPMDFTPVSFKALEFLAFLMDKTPVDTHLVHVIQVNEATTGFEEIRKQVN---F-EFSSAVVYGGLTSGLTRYAEKNGIDLIIMGTEGADGWFERISGSEAQHVVRFTTVPVITIQR- -> ---MKKIIVPIDFSEEASHALNFAIEFNERVKGEIVLVHVVEMP-VHNKLDEWAKRPKDAGH-KVHVHMKSGNAFTNISKLIAEENAGWIIMGSKGASGIREVFIGSNAERMIRHAECPVIIIKG- -> ---MKKILVPTDFSDCANEASRVAIKIALKTGAELYFLHIHYTIPTKSQLHQVVKEAGSHGV-RANELFVLDTGYEKIENYIAPFGIDFIVMGTHGSHGFKEIFVNTNSQKIIRESTVPVLVVKE- -> ---MKNILVPTDFSENCTKAAHFAIKMAKSYKAEIHFLHQMTTPVDKAKLRELERMAEHEML-KCRTFLQFDSGQKDILEHSGHFHHDFIITGSSGTKGRVREITGSNVEKIVRKANAPIIVIKE- -> ---IKQILCLTDFSESAENAKAVALSIAKRTNARINFVHGMTVGLIKKRLSVLVEECKKDGY-DCSYEIRYADGQRNMSNQLLQGEYDLLIMGAQGFGDRSQFSIGANAVKILRTAKRPVLIIKD- -> ---MKNILVPTDFSDNCEKAAKLAIEMAILFNSEIHFLHQLNTPVNKSKLRALDKEAEHKGL-TSRTFLEFVSNDKAILSHSDNFHHDFIITGSKGLKGFLEQLLGSSAQKIIRSARVPILVVKE- -> ---MKTILVPTDLSPISLQALERAAELTRTYSARILLLHTVIDEDLEAQLKALLSDPLYQGI-EIQIEV--GKTLKGFLDCLSDYNPDLIIMASEGASGLKAWTEGSHAGAVMRQACCPVLILKE- -> ---MYKILCPTDFSTVADIALDAAILLGKTLSAELHLFHCTEFPTYKAELTKRKMKIKAANL-PCLIHVDKGNFINRISELTTLIAFDFIVIGSHGASGKREWLLGSNTQKVVRRLHSNILVIKD- -> ---MKKIIIPVDFSQHSEYALETGAALAKQHNAELIVMHMLELSESNKEFEKFLDKPYLEGL-SVTPLIKHHKVLKEVSEVASYEKADLVIMGSRGHSDHDGVFTGSNTEKVVRYSDTPVLVVKS- -> ---MKNILVPTDFSKNCNKAEELGIEMAKLYNSEIHFFHLMKTSVDKSKLRELEKKAEHEGL-KCRTFLQFDSGQKDILEHSGHFHHDFIVTGSSGTRGGIRELMGSNVEKIVRKADVPVVVVKD- -> ----MKVLIPTNFSPYAEFALGLAKHFGSKMPVEWHAMNVVKAHDDESKKQELANWSSSLPG-EVVNFVASGEVVNQISAYIRKYEIDLVIMGTPGAFGAKNLLEGSTAEKIMRVAGVPVLSVKC- -> ---MDTILIPTDFSEHAHYALEYASFITKEKGGKLIILNVYQHHKE-----SYLKGVDYEFI-TEKGIS----VSNTISKVGIDYHVGLIIMGSNGVSNIEEMLLGSNTENVIRKSHFNVLTIKH- -> ---MKTILVPTDFHVAAENAMAAAVKLAKNMDAKINLMTMFKFPKFAREIERWK--EWYPDV-EIEGIV--KENFDELIPAILSEEADLIVMGSEGANGWKDYFQGTNSQNVVRKADCPVMVMKE- -> ---MKNLLVPFDFSKTSNHALNLALSIAEKQNTTINLLYVVQDPFSKKELKHVIKKFNNNKI-KTPYVTVNASVYKGILKFIDTKKTGLVVMGTHGISNLKTKYLGTNTERVFRMTKKPVIIVRD- -> ------------------------MEMVARAKAEVVVLHAAYVPVLKRGYEKMKNESGVRGV-SVSLDIVHDNLISAIQHHVDRKQTDLIIMGTSGASGIREVFIGSNTEKIVRFAQAPVLAVHK- -> ---MKRILVPTDFTDSSIFAICTAAGLVEKFAAELILLHVLDEPEDAKKVEKILKLADLQDL-NYHYQQVKG----DLIESIVNQPSDLIVMGSHGAHGLESFFIGTNAEKVAKRAECPVVVLKD- -> --NMMRTLLAYDGRQQ--RVLDYAIDHALAYKSTLFIISALATKKLKGSLEAAKQRALDKGV-DVHIMTGAGDPATEIVAAAERIGADTIIVGHRDKTVLDRVVLGSISENVLRNARCTVIFVL-- -> --MLRQVLLAYDGSPSSEDALNLACDLTRGLGATLQVLTVIDQSSALQRLRRLEPMALRAGF-SLQLEVLIGDPAKEILAQVSRLPADILVLGRSRPSTIDRLATSSVVELVLPEAACAVLLPK-- -> --TDMSILIAYDGRQATEAALEYATKLSVSLEEPLYILNVVSKETVQEYMAAASQKAMAAGA-DVHTIIEVGKPDDVILEVATNFQCGAVVVGRPERSRLDRMVMGSVSQNLVENCKCPVIIVP-- -> ----MSILLAVDKNPNMDNVVKFAIDLAAWRHDEIYAVHIVTGKDGLLLLDRIKDRAAAFGV-FLTPMLESGSVYETILNAAIEKKADLIVVGSSSGKGHQDSRVGSVSEFIVHNAPCTVVVVK-- -> ----MRVLVATDGKPWSDKAVEYAFALYKQFKPTFVALYVVDPKNGMRILGRLKIRGADIGI-EVATLLEAGDPMETIALAADRIKADVVVLSKNPEKSGGGLLGGSTSDFVIKNTNCVVIVVR-- -> --MYDTIVVPVDGSPEARTAAEQARDLAADLGSSVHLFYVIPATASSRVAELATDVFGDSSV-DVQTTVRRGDQETLTLAFLEEVDADLVVLGRKETPEVRDYLFWSTPAQIVRESEISVLLAHP- -> --MYNKVVVPLDGSKLAELALPHLEVIGKGCSPQILLISVTERITAADYLCKISEDLEEKGF-NVTATVLMGNPAQQIAWYAAEQSADLIIMASAGKSGISRWNMSHIADKVIKETCIPVLLVSP- -> -MEKEKVLIPLDGSDTSRTILPHVCHFCDAGAEVIILRAKSVPSQLREELQGDIDYLEEKGY-TVSVAIHFGKPVEEIIFIAEQKSVALIAMASHGRTGVKHLLKGSVTEDVLHHINIPLLIINA- -> --AMKRILIPVDGSETSLKAVKALLDARRYDPERVDLLTVQMPLEGETAVQAASALLTQAGV-PFDVHIEAGAAAETITRVADETGAHEIFMGTRGLGSVSALFMGSVATGVLSLTELPVTLVK-- -> ----TSILVPTDGSAAAGHALERALEIADERDGHVEVYVLTVVDRARKC------LVDDHDA-EIHGAVRRGRPARVVLSYADERDVDLIVLGRTERSDVSETLFGSTVGRVRERATVPVIVVP-- -> ----MRALVPLDGSETALAIMPAVRRLAEMAPGIALHLVTVLDPEWREKLEEVARELPGTDT-HV-HIEWSHHTAKAIIELANELDVDVIAMATHGRSGLSHLLAGSVAEEVIRDSGRPVLVVRG- -> ---LRRILVPVDFWRASLKPLWYASAIARAHGAKIVLLHVTSPVQIRKDLSHLKKNHLPPES-IEDVIIRSGKASEQIIRAAKEFEADLIVLYAHETNESSTVGSHETAERVVRLAQCPVLIVRS- -> ---LKTILIPTDCSDHSRISVKYGIQLAKENDAEIKLLYIQENVLRMSQLQDFWD-SFEEEL-PCEREVRTGDVVSEVIYAAKKGAFDLIIMSSHGYKGLVYSMKGSTTEKVTRYAPCPVLCVKN- -> --MYRKILCAIDLKKKADKAFEKAVELAHQFNSKIVLLNINDDFSAKKKLDDLKENLETDDI-DISVLLRKGKPGEIIIKTSQDIEADLIVLGANGKDSIADYFLGTTASYVVEHSQVPTLTVPL- -> --KGRVVLVPTDGSVHSERAYEWYVKNVRMPSDCVKFISVIEPVAGKKLCQQYMHKAKADGI-TSQAFLHDNKPGAALVKSITEHKADLVVMGNRGIGAVRRTFLGSVSDYVLHHAHVPVIIVPPS -> --AARNVLLPVNLTEHSRRALDWYAANIYKSDDVIHVLYILEPSLSKTLGHEFLLRIQERGL-QGNYVLSGTRPGEQIVSYAKENNVDLIVMGSRGVGALRRTVFGSVSDYVLHRVNIPMAVVPFN -> --DGRRILCAYDGSKGARAAFEFASERLACPSDSIVLYEAVESIRINQSLQGLQELAMSTKV-PCP-VVMMGDAREAIPEYIAKHPVDLVVVGSRGMSAIKRFFLGSVSTFLVQHCTVPVVVVPPP -> --QKSRVVIAVDGSEHSDRAFEFYSQNMHKKGDEVLLIHANDIAESKKMLSRFEKKCKENKF-NCKLFTKVGNPGEVICDFTEEKNADQVVLGCRGQGTVRRTFMGSVSEYCIHHATTPITVVPPP -> --VLRKVLIPVGGSSESKKALAWYNDNIKRDGDLVLFVHIIEPIKARSLFKELIHEANKHDI-NHESMIQDTRTGPALVKLIQEKNIGVVVMAKRDLGFWRRNFSQSITSYVLNHVNIPVSVIPPS -> --LGQKVLFPIDSTEGCEKGFRWYIKNYYQKGDEIILAYILSPSEARHTFEGYTQLCNEKGI-DHTTILYGTKIGRTIVRAIQENMVDSVVLGFHSMGRVKRAFLGSSSGYVVKRSSVPVVIVPPI -> ---MKSIIIALDESTYSQVIARQGFELATVFKSTVTILLIRNNEKLMIEIQELAKIF--DTI-EYSMTTLEGDPMEEIIRFVTDNTADLLIVGTHGRTGLDHWITGSVAEHVIRHATIPVLVIPY- -> ---MSKIMIAVDLSSYSAGVVAAGIELARSSKAPVVLLTILDKAQVVSSLEVYKDTY--PDV-DITVNAVLGSPNEDILEQVSEQGISTLVMGTHGRTGLDHLLIGSTAEFVIRHSQVPVLVVPY- -> ---IQSIVIALDESDFSPRIASRGFELAVFFNATVELLLVRNNTRQMSNIRQVTQKY--HLV-EHSTTILNGDPQEQIIQFMTHSNADLLIAGTHGRTGIDHLISGSIAEYIIRHSTIPVLVIPY- -> --LPTKILLATDGSREAGLASRAAADLCLRTSAELHVVHVWTNLGARVLLEQQADKVRSGEVFVAGTHLKEGRIAEEIVGLAENLDVGLVVVGGRSVGAIGRLVTGSISEGVARLSTAPILLVRG- -> --VYRTILVPLDGSEAAETVLELAMNLAVRSGSVLTLLHVCSQRDMSKICETVQCRFEDVTA-TVFPVLVKGEPAEEIVRYAEENEASVILMATHGRSGLAQSVMSDVTNRVVRNSLVPVWLTRT- -> --MIRRVLIPLDGSELAEQVIPHLLRFVAPERTELLLMTALSEQEVSERLLEVAQQLNQNGF-RVESKCLAGIPAESILRLAEEAYVNLIAMSTHGRTGLGLTLLGSVADEVVRNARPPVFLVPA- -> --REPNIMIPLDGSRFGEAALPVALGLAQDLRGQLKLVSVSGPEELSQYLETLGTRIERSTV-PVSRVVLGGSATKALAEFNDLSHPDLIVMSTHGCGPLCRAWIGSVADWLIRHVATPIMLVHP- -> --MYKRILVPLDGSLTGDRVLPYVRNLGRKLDAKVKLFRVFD-EEVMTSLGMTKTNLESAGV-AAQPDHDCGTPAQHIVAESKKVPDTLIVLSTHGRAGLGRWVMGSVTDKVLHSVKTPMLIIRT- -> ---MPTFIVPLEYHGISERVLPWARALARRLAAPVVLVAVLERAECRAYLEEVAQTFPQE-A-PIRIVIEEGDPALVLTRLAEETADPLVVMAAHARAGWRRVVLGSVTAQVIASGVTPVFVVPA- -> ---MRSLLVPLDGSLLAEAALPYAESIARGARAEVVLFTAID--WAYTYLEQKRRRLETMGI-STRIEICFGPAAQSILTVAERLGVDLIVMGGRHPHGPEPWSCGGVCMRVVEFCSRPVLLVQP- -> --MAGRLLAPLDGSRLAETVLPYVATIAPALQLEVVLLQAAG--QSKAYLDTVSERLAAFGI-SALVLPASGPPEDAILDSIAQLNVHLVLMATHGRSGLEELLYGSVTHKVIRNSPVPVLAVRE- -> --MFERILVPLDGSENAEIVFPYCADLVAKFASTVILVTVSE---YRTYLDHALGKMRQDTV-TLGSEVLFGDPAREILRTAEEKDARLILLASHGTSAEGPWFLGHIAAKVLRATRRPVMLIRE- -> --QIKQVVIPLDGSAEAEITLPYGLALAQHFQAALELVSVDE---FRSYHQHLDERLKSA-P-AWQTYLRSGKAPDEINKFIAEKNADLVILSAHGSSGRGAVLLGKTAAKILSGIIKPAILVQT- -> --RIEKVLVPLDGSDGAEITLTYALALAGATGAELTLASVDE---YQSYLELLDKRLSELTG-RWQTRLASGKAGDELLRLAGETGADLVVISAHGASGKGAAQLGKTASKILSDITRPVLLIKS- -> --MIKEVVIPLDGSAEAEITVPYGMALAQKLGAQLDFVSVDE---YRNYLRHLDERLKAQ-R-AWQTRLQNGKAAEEILRFIEEHVADLVILSAHGASGRGSALVGKVANKIMTGTNKPALLIKS- -> ---MQVLHVAVDESRRSLQGIHLGELLHRQWGGTMALVSVVA--KRRAALHDALDRQELGAY-RESLEIVTGDAADVLAGLASDPGEGLLCMTSHGRRPASELLLGSVAAETVRRAGALVVLGGP- -> --PAGSLVVPLDGSAAAEYALPLAARIAAGYDVPVAFVHVVE--KFRGYCATLAQRYG-L-R-AWTSAVLEGRPADEVLAF--AEGARFVCLASHGRGGFQAMLIGSVADKIVRGAEIPVFFVPA- -> --RPKTLVVGLDGSPASRGAFAQAMILAASLRGRLVAVAVVPGLPYEEALAEAGEAAAAASL-PLKKVIETGEAFERLVDVAEAEEASLVVIGDARRAYMERVLLGRNVAKVIGYSPCDVLVVPE- -> --LYEKMLVACGSEPSGLHALKEIIKYIKEDGKPIIVLSVVPFYPFKEALEKAKEIGDQEKV-IVKTVLEEGDPFIKIVDTALSENCDLIVLGRKKELGLMGKLLGANVARTIGQSPIDILVIPE- -> --RLERLLVPVTGDEHSLYALDQILEFAATRKCRVAVLSVVPPYPSELALARALEMANARGM-DIDCLCEEGEPFEVIVDTARRLKADLVAMGVADRSALGRLVRGNVPLRTIGHSERDVLLVPQ- -> --NIENILLAIDFSQASKDALKMAVFLAGKNRSRIHLLHVVPRLEAEGMLAEYVEELRQGGVSETQAVALFGNPLEEIVGRANSLDANVIMIGSGEKDKGDRFPLGITAENIIRSSSRPVWVVKR- -> --KYKKILVAFDGSVSGTNALLQSFRLATEEKSWITVATVVPAYPGEEILSRANALAKKEGA-LIKTVLEEGEAYDRLVDLAEGENCGVIVMGRRGSSSTERSHIGSVTARVIGHSQRDVFVVPE- -> --KYKKILVPVDGAASSLHALQETFKLTQNG---ISVISVVPPYPCDQAASLALDLAAEAGV-EISVACPVGEPHEVIADIAASEDFDLVVMGLREDQGIIRFFMSGPTAKVIGYSTKDVLVIPE- -> --MFERLLIAVDGSDCATRAARVGVAVAAKYGGTVDAVAAAHDEDAQRVLADVEAIGEEAGV-TVESRVVTGRPARSVVSLADEVDAGAIVVGRHGHSGFRERLLGSTTERVLRNTDRHVLTVPA- -> --MLERICIGVDGSDCARRATAVGVAIAEAADAHVDLVYVRKETDANAVLEDALESCEDASV-QVDGHSLTGKPATRLVSFADEHDADLLVLGRIGRTGLGKRLLGSVVHSAFRQSDRPILTVPE- -> --EEQTFLVAIDFSDCSREVLRWTKSFLAKKPSRIIALHVIDSNA-KAKLRDFLK-ENMREE-HVKMVVCEGTPFLEINKKAVENDVDMIIIGSCGKTGMSQIFFGSTAEKVLRFITRPVFCIPP- -> --MPKKILVGVDMSKLGENVTLYGLSLAYRLDVDVTFIHVLPHPIAQKRLTYYLKKAEEKDPKKREIVVLEGNPAETIINYAKEKGYNLIIVGSRGHSAFERIVVGSTATNVARYAHCSVLIHRIG -> --MARKILVGVDLSKMSESLIAYSHSIAHRLNDEVIYIHVLPRLIAHKKISYWIQKAEDQFKHEHKILIEEGSPGEVIIQKAKEENVSLIIVAYKGHSTMEHILIGSTTTTIARHAPCSVLIYRPG -> --ITMKILVAVDFSPVGREVAHAGYRLAKKIGSEITFFHCAPQTMAKQKLHKIMEDVFAENG-EIEEEVVFGEPGDELLRFAKEKKIDLIIVGYKSYSAIEHLLVGSTASKVARYAPCSVMIYRPD -> ----MKMLIAVDFSPVGREAAFNGYRYAQQLGADVTFLHIVPAMAAAKEINTLVDEIKEKYG-CGVSVNVADNPGSEIIRVADSDGYSIIVIGNKGYTTLERMILGSTALKVVNQAKCSVLLYRHQ -> --PFDRIVVAVDRSPASGEALARAISLSRALAVPITVLTVVPRLAAESLLANARTLADRNGR-EARVELMRGPPSEAILDYLDESESHLLVVGSRGLSPTRGLFLGSVSTA--------------- -> --MFKNIMVPLDGSTHSSKAEDIAINLAKRLNAKLTVVYVIDEIEGDKVLDDITKKGNKSGI-TVAIHSITGDPLRDMKVIAEKTKVDSVIISSHGKNSVEDLTIGSVADRVIKTFDIPVILIK-- -> --MFDIIAVPVDGSDYGYKAADVAIEIAQKFNSKIAAVHVLEEFEGNSILSKITKKANDVGV-EVTEHLLTADPLRDMKFIVDQTRADLVVIHAHGSNNNRDTQIGSVSERLLRTSEVPVLLIR-- -> --MFKNILVASDGSKCGDKAVDIAIDLASKYDARVAALYIMDFGAGGAVLDDITAKGKEKDV-VVVEHIITADPIQDMETMIRKINPDIAIFGAFGKSTDKYDKIGRVALNALKVAKVPVLLVK-- -> --TFKKIMIATDGSENAEKAAKVGIDLAKSVGGKVIAVYVMDEREGKNALKRIQKIGRKKNV-VVDEILILGNPIEDLPKIANKVNADIVVLASQSKGKFERIILGSTTKSMLENCNVPLLITP-- -> --MFKRILLPIDGSENSKKAADKAIELAKELNSTIIVTNIMDQSKSNEFIKKIVDLILKNNI-NVESMVLFGSPMYDIVTIARKSEADSIIMGKQGINYSNSRVIGSFTEATLKNVDLPIILI--- -> -MTFQTIACCTDFSKNADVAVRTAGTLAKKFDAVLEVIHVVPPPDNPNLVLQVEEKLQPGDV-KVRYVVLDGHVSTEILNHLDESGCDLVVVGSYGLSGMGLVIFGSIAKRIAHKANCSVMIARP- -> --------FPIDDSESCTSAFTWYLNYIKLTGDFITFVHVVEPIRSKALGLSYMNLAKKAGL-ESRFLHVETQPGRAILTSAKNHNIDMIVMESGGQGALSGVSLGRVADYVVHNSTVPVVIVHAD -> --------IPMDASEHSYRALRWYADKMNNPADSLIFAYIAEPPRGKLMAAEVRQRCTEMGV-KPRLERLTHGAGPALVEIAEEQAVDVIVIGSRGLSALRRAFLGSVVDYVLQHANTTTIVVPPP -> --------LAYDNSENSQAALSWFARLNAEDRHQLVIFYSVEAPQIDRVRKRCLALCQQLGL-PVKIDKYEAEPGKAIVAMATELDAAAILMGTRGLKRLQRTMLGSVSDYVVHHAHRPVIVVPLT -> --------IPVDVGEPSKSAVIWYMNNLRKEDDQVLLLHVLEPKVGDKLQKTYKKIFDEQNI-PFDQMCFGKKPIDSVLEIIQSHEITCVVMASRGRNMIERTLLGTVSDGVVHHSSVPVIVIPPS -> --------VPIDEKEHCVRAFDWYVENYRQERQEIILLHVYNSLQASGMLEGFEQKCKHFQM--PFTRIELGSPGDAICKVAKEENITCIVLGNRGLGAFRRTILGSVSDHVVHHSRVPVLLVPPT -> --------IAIDSSPNAKKAFQWYVDNLHRPGDHAVLVTVVHIRELNRQLQELAVMMKDAKV-HGTKCVHAARASKGILAAAEDCNASCIIAGSRGLGIFQEASLGSTSEQLVHTSNITVVVCPD- -> --------FPIDDTEHTLNAFKYFLDKFRLDDDHVILCHVVKGIDHEKLAEKYRLEAKD--I-ETLFELVFGKPGESIVQFAKEEKVEAIVMGSRDLGTFARALNSSVSNYVVHHADLPTVIIPRK -> -NHYQNILLAVDFTDHGQTVAQKAQSLAE-FSAQLHIIHVLDNIYD-DLLEAEKNKFIQLGIAAERRWLIWGEPQQEIIRLAAQERIDLIVAGSHGRHGLAV-LMGSTASGILYHVQCDVLAVHL- -> -SSYQRLLVTTDLSKDCEFILAKAVEVARTTQAELHVLHVAPSDKEMDYTDQVKSLLTRYEIA--RIHVHTGTVKKVVNEYVELMAIDLVVLGVHNRYGLKL-LLGSNSDQLLHSVSCDILAVRI- -> -GEYTHLLVAVDFEPESEVVVARAQRLRHLTGARLTLLHVIEHIYEAELLAVAVRQMDQLDVA--DRLVRVGATGHVIDDVAEELGADLVILGRHGRHGLLG-LFGSTARTVLRHSTCDVLCVKI- -> -MPYKHVLVAIDLTDECESVIHRASMLAKDSGAKLSIVHIVEPMFQQQQFDQAKEKLKSLLRFPLESHLVYGQPRQEIHQLAKNKGCDVIVVGSHGRHGLAL-LLGSTTNDVVHGAPCDVLAVRL- -> -APYQRILVAIDCSDESADILCRAAGVLEGNTGELHLIHVIEPLYQSGLVKQARETALQYQIGEDRIHVELGSIEKTIVDKADALGVDLIVVGSHTRSGLAL-LLGSTARGLVPGAHCDVLAVKV- -> -TSYRRILLVVDLSEDSLLIGRRAQMLAEALGAEIELLHVVEFVPEEELLVRARQRLAELGIPENRCRVEAGNVKSEIVRIARERQVDLIVLGSRERHGLSI-LLNLTEDTVLHAAPCDVLAVRV- -> -HVYQHILCAVDFSSLSEAACQRALALAEQSGARLTFLHVVEYFNAYEA-IEERARLARLACEAAQVLISPHSAWREIVRFAGATGTDLIVLGSHGFHGVAT-LLGSSANALANRAPCDVLTVRH- -> -QHYRHILAPIDFSARSNDVIKRALELAEAHDARLTLLHVVQDVFREQHLASTEKKMHQYKLP--DRAIEEGISTTAILDFATEKQVDLIVIAHSGKKGLLG-FLGSTADSIVKSANCDVLVLRN- -> -HSYRHILCATDFSAASDLACARAAALNECFGAQLTLLHVVENF-QQYREDEARRRLRRVGFK--QQVKFTTESAHAIADYAQAHQIDLVVLAEHEQRGLKA-LLPTAIEHLPQTQVCDVLIVPM- -> -NEYQHILVAVDQSADAERVGRQALIVAQRNHAKITLLNILEGIADSEIIAEAKKSMRKLGIP--DTMVISALSTEGILRAAEELKADLLVIGSHTRSGLGV-LLGSTSGSIINDSPCDILTVKV- -> -SRYNTLLVALDLTQDSAQVLSGAKKLATAGH--LHLVHVAEHPSELQVRQELFPRLQGMALP--HLHILFGDAPQEITYLAGKLGADVIVTGSHGEKGLKR-LLGTTATDILHQAACDVLIVRI- -> -SLYNSILVALECGKDAQQVLNKASALAEQNPSAKIHLVHVVLDWQEALAQSGADYLREAGL---NLIMCFGPPAQQTLKQADNLNADVIVAGSHSRHGFEV-LLGSTAHKILNLAECDVLLVRC- -> -SIYKNILVAIDLHPTCDEIILKAHAFVKEGQGRLSVIHAVEHIAEGEMLSEAKKQLAKFDIS--QQYVEVGSPKIVILDKMKELKTDLIIIGSHGRHGIGI-LFGSTASAVIHHLSCDALVVKI- -> -TVYKHILIAADLSEHSD-IAKRALEIAKCVKAKLSIVHVMAHA-EANLKKEAKKRLTKYHIA--AQYLTEGSIKSAVTQLAKKIKADLIIVGTHGREGLEL-LIGSQANGILHAAQCDVWVIRI- -> -ATYKKILIALDFQSDNSEILAKGREIAGDNAAEIFLVHVNEPLTEVSIRKESEAHMAELNLR--NCIIKEGRPSAEIHAICKERDIDLVVLGTHGQSGLQL-LLGSTANSVLHGSTCDVLSVRV- -> -NNYKYILLATDFSKPARAAAQRAAKLASCFNARLCLLHVVDHF-AVYLSERSIKALEQLEHD--THTILSEHSAHEITQYATQNKVDLIVIGHHGHHGISN-VAGSTSSAVVHRAECDTLSVQS- -> -ASYKHILITSDLSDSSIILCQKASALAGLLNAKLSIIHIVEHLGEEELADEALINLHYHHID--DQYVIVGDKKEEIKAFVIEHHVDLTVVGAHDRHGLDY-ILGTTADNMLHALPCDMLAIKV- -> -AGYRHIIFATDLTEAADTAATRVVDQARCSGGRVTLLHVVEHL-ENYIRERVEKRLARVHLG--RHVALSDYSARAILEYLGEQQADVVVLGALG---NPG-QLGTTVDHVAASAPCDVLIVQG- -> -MANPLWLVATDFSPGSEAAFRRALELAPPLGAHLLLLHVVLDL-QHELEEEAGRKLEEARGH--ARVELRRGTPAAIFAAAHDAKAAMIVVGQAAKAGRAV-CGGSTAAALFHHPPCPVLVVPA- -> -SMYKHILFATDLNTDTV-VARHAVELAQLFQARLSLAHVVTGL-DLIQVQDAHQRMEELGETQLKWLLNSGPVALQIHRLAVEQEVDLIVVASHGQHGFFK-LFGSEATDILEASSCNVLVVKI- -> -KRYAHVLAAVDLAENSEKVVAHAKEMAALFGAKVSLIHVVEPLYESELYEEAKKQLAEFGID--NISVDMGPAKVQILGKAEEGKVDLIVVGTHK-HLFLG-VLGSTANAIIHNAKCDVLTFRV- -> -NLYKNILVAVDLSQDSAVILDKARSIAKAYDAQLNLVHVIEPI-HQEATEQAKQSLMNIDIP--RMHTLLGQPAREIKELANEIKADLIIMGNHGRHGWEL-LFGSTSTGVAHGVNCDLLTVHV- -> -KKYQHVLFATDLDERSESAAEYARDFAALLDAKFSMLHIVQVV-EQQIVEDAHAEMAKLGVE--SCQVVKGYPKEDLLRKAKQMGVDLIILHGHR-HHWLG-MLGSTANSIVNKAECDVLVLSA- -> -PTYNNILVGLDLAEDCTQILRKAADIAGSFHAKLHVVHVVEPLYQGVMENQAAERLEEVGVSVEGHRVCIGQAAGELHRLAEEENMDMIIVGSHSRHGLAL-LFGSITKGVVQNACCDVMALKV- -> -MAYRNILVALDTRDEAAEVLESVQKVMSQEDSSVSIFHVIRPLDESKAIDQAFHWLEGHDIS--SIDVVLGTPTTEIWRKAQQINADLVVLGTHGRHGHGK-ILGSTANGVCNTAPCDVLAIRV- -> -NGYQHFLFATNMSDACNKVIAKR-QFADVFEAKLSVVNFVEP-TETSRQQAAKEELLALNVS--MQHVIVDTPKNGLFDLVESLGVDLVIIGRHNKMDFSW-LLGSTTNAIIHAAHCDVLVLHE- -> -QNYDTILVPIDIYSDYELVVNKAVAIAGDSK--LHLLYVAYPQYSEEVRVQALRLLKKHDIP--QVNVEIGSPADEIHHMADKLSADLIILGTHGQSGLRL-LLGSTANAVLHGVKTDVLAVKI- -> --MYKTILCAIEASTEGKLVLAKAAAMAKLYNSKLLVMHVLPYK-QKELKEKVTPKIEDFGV---NRIIKVGKPYELICNEAIKRKADLIMLGTHSKKGIQA-LIGSTANGVANYADCDVSLVRI- -> --SYQNVLFGYDGSPQSMIAFDRAQQIAKRNNTKLIIAMVVKPQQKAKELSRLKQVAESEGVKEVETRLVIGNPRDELTYNLKEEHVGLIIIGSTGLGRVAQVLIGSTASYIVEHANVDVIVIKEQ -> --NYSNVVVGVDGSKASDRAFKKAMIIAEHNQARLAVIAVINDRQIQSMVSNYVEIAKDRGL-NAVGAIDYGDPREILTSTASDYHADALVVGATGAGIVSRLTMGSTAAYVVTHSPVDVFVVRTD -> ---MIKILVAIKGADSCSKVAQKAQELALLCKGEVTFITIVSNETCSMVYGQCERKLGEKGL-ETKRVVKEGYPAEDICKYADENNFDLLVIADKGDTKLKDKLLGSTTEKIVRESKTSVLVVK-- -> ---MFKILVAVKGSESCSAVAQKAQEMALLCKGSVTFLTIISTKTCSTLYGQCEVELGEKGL-ETERVVKEGYIGQDICNYAEENNFDLIVIADKSDKTVKDKLLGSTAEKIIKHAKTSVLVVK-- -> ---MQKLLLAVDGSKSCSKAVGKVYELADDMDLDVTVLTVLEKAEAKDMVDTCSEGLEKKVS-KLKKEVKTGVPSDVICRTAEEGDYDFVVVADKGRGAVKRFLMGSTAERVTRYSPISVIVVK-- -> --ASRRILLPVDGSKHSDRAVSWFLANLYRPGDFAVLAFVLEPHEAARLKAKFYQACREAGV-PEHFQLVGSKAGDTLVRYVEESSISCVVIGSRGLGKLRRTFLGSVSEHLLHNAGCAVIVCPG- -> --FRAIVLIAVDDSEPAEFAFNWYRDFIHKPEYYTVLLHCTDNDRMKRIEEKFGHLMEINGI-VGKIRKGKGKPGEAIVKAANEEGATMIVTGTRGLSKLKRAFLGSVSDYVVHNSPVPVITCRV- -> --PPRIIIMPVDDSPHCERAFNWYLKRAHRSEDKLILVHVIPPREGRRVLEKYAQKCKKEKF-IYEITKADSNVGNVIIETADEYFANLIVIASRGMSKARRTILGSASHYVVYHAGIPVLVVPP- -> --MGRTVLLPVDPNENCKHALKFYINNFFNKEDTLIFLHVIDQSNGKALAHKYLAWGRDAGI-NVKAFRSDPKAGEAILTVADELDVDHIIMASRGLNALGRTFMGSVSTYVVHHSSVPVTVVPC- -> --PQQRVLIAVDGSSHSQNAFDWYRTNLATPGEDVILFHTGSPNRVAQLEESMMEQCKRHSM-QCRWKADSLSPGPAVVDASAEEKADLVVMGTRGLGTIRRTILGSVSEFVISHSRRPVVVVPP- -> --SANVVIIPVDGSKNSERAVSWYLEHIHSKGDRVVFIHAFDPPKARSLLKGYDEKFATLKQ-LSYKMHDSGKPGEVIINYSKKENGTVLIMGCRGLGKLRRTLLGSVSDYVVRHSSIPVIVIPP- -> --MFTRILFPTDFSVHAKKVKTKILKMKDCGIKELVLLHVVNKKSAELKLKGWGKDLESTDI-TIKYDVVKGNPFDEIIEYSLKENCTLIIMGSKGLTEAEELLIGSTAEKVARKSKIPVIIIK-- -> -MTTMSILLATDGSPEALSAADWLNRWANPSTVEVTVATVISPPQAQKALDDTRAQLT--RCPPVKEEVLLGAPPKALVEYATTHHIDLIVMGRRGHSALGN-LMGSVSFGVLHRSPIPVTIVS-- -> -VHRGKVMLATDGSPTAINAASWLNDWPHPEEVDVVLATVIAPVTARQSIYETRRKLT--QEFSVKEVILRGPIAQTLVDYAEKHDIAQIVLGCRGHSVLGN-LLGSISFSVIQRSDLPVTVVG-- -> ----MTLLLASDGSEGALKAARWIMEHFGPEHWQVTVASVSRTPEARQACEQTMTVLE--GW-HVDCTVLTPSIADALIGYVRSHPVDAIVVGRRSHSLSRH-LLGSISSELASHSPIPVWVIP-- -> -FLFRKILVPVDGSESSMRALKVALDFAQRYGSRITVIHVKHPSDATPIINAAKKLAGERGV-EVSVKVKASSVASEILSEAIEGGYDLIILGARGNTASEDIIIGSVALSMVVNSATSIMIIR-- -> -YMFRRILVPYDGSANSEKGLRVALELSAILGSKITVAYACEKDCSE-LLKRAREIAEARGI-RIETKLIESSESSEIVKEVNSNSYDLVVVGIRGKTEYEGVLKGSVASSLFVNANVSFLFVK-- -> -FWLRELLVPVDGSGSSMKALDLAVDFAMRYGSRLTVLYACSECSAD-VRKLVEDR-VGGRA-EYRFVVSSSSAANEILKTIAEGSYDAVIMGARGTSINGDINVGSTAIAVAAHAPVTVILVR-- -> -MWFRRILVPVDGSENSMRALELALDFSMRYGSKVTVIYACNRCDAE-VKARVKEK-LNEKI-EYEYRTVDSSISNEILRTLSEGVFDAVIMGARGNTTNSDINTGSNALSIVVNAPITVIVVR-- -> -MWFRRILVPVDGSESSMRALELAVDFSLRYGSRVTVFYACDRCDKE-IRKLVENK-IDNKI-GFEFNTTDSSISNEIIKILSEGVFDAVIMGARGNTTNSDINTGSNALSIVVNAPVTVIVVR-- -> -FSLRHVAAVLDGSRASLRALPVLKDFAQRYGSRITVIYQGSDDFLS----LVKESMSGAGI-TYTV--E---KPSDLLEFIRNKAPDLLVLPLEGRTGAEALESAGPILSALAYTESSILVLR-- -> ---FRNILFPTDFTTHARSALKYAAAFAREGRGRVVLFSVQTAKQLRAQVKDLLIDSLFDGL-EVEPVIVEGEPAHEIAKAVRDYDIDLVTVVTHGRRGLARALFGSTAEEIIAEAPCPVLTIRP- -> ---IRNLLCAVDFTEFSYQAVRYASGIARHFGSHLFIQHIVAVPIAEEELRRLQAEADIQDL-NITYLLNDGSVRSQILETVAQKKIDLLVLGTHAHRGVRRLLGGSLAERLAHEAICPVLVVSR- -> ----RKIVIAVDGSANAKYAFRWYLKHFRMPDDRVLFLHILQAPRVRQIEEDYIAEGQAVAL-NCAFSEPAEKIGEGIIHTAQSLHADLIIMGTRGLRAVSRALLGSVSDFVTRQGVVPVTVVPS- -> ----RKIMIPLDGSSHAEEAYKFYMENICRDGDQLVIAHIVEPPKAAALEEEVHYRAAQKKM-KMDYVEASKRPGDALVDIAWRTNCHMIVMGTRGLGDVRRAFLGSVSDYVIHNSRLAVTVVPS- -> ----RKVLVAVDGSEHSHAALDWYLKKCKRDDDMLYGCIVKQQPRANKEEEYFEMTVVPTKM-KHEFLDPDNKPGERICEHARNKKVDLIIMGTRGLNTLRRTLLGSVSDYVLHHAHVPIAIVPM- -> ----RTVCLPVDGSEHSKRAVEWFIKEVYRPGDHVLFIHSVELPLTNKLNNEYGYICESKNI-PYEFVKNGSTPGAGIIEACEERPVDLIIMGSRGLGRIKRAIIGSVSSYVVHNSNVPCITVPP- -> ----RKVLIAYDSSSSGDYALQWAFDGLIQDGNDVVLVTAVEQSKVSLLSVRYASLFRKRDI-SCQSFILEGDARDVILEVADKTRADCIVMGARGLNAVHRAVLGSASLFITQEAQVPVVVVK-- -> ----MKVFIAVDNSELAEKAFDWYYRELHKDGNDVLVAHSAEYPKYEALKEKYLKKIEDQ-Q-SAKIFEVHEKPAEGLVKMAEKSHCDFIVIGSRGLGAVRRTILGSISDYVMHHAKVPVMVFHK- -> --KKLKVMVAIDESKNSFYALEWAVEHLKDVMGLLTLVHVNPSGQSTNLFTPALELCRAKMVGKTETMILEGDPKEMICQAVEQNHVDLLVVGSRGLGMIKRAFLGSVSDYCVQHAQCPVLIVRPP -> --KKTRIMVVIDESDESFHGLQWTLDNLFGCIITLSLVHVQRAGQAKALVSRASDMCKDKMN-EVETLVFEGDPKEKICRAAQEMHVDLLVIGSRNLGKFKRSFLFTFLILFFLPFAT-------- -> --MIKVIMVGIDESDESFNALRWTLDFLFVSIGKVVLVHVQQPGETTVLLSRALQMCKDKMVSEAETLVLDGDPKDMICQAAEQMQVDLLVVGSRGLGKIKRAFLGSVSDYCAHHAKCPILIVKPP -> --TPRTIMIAYDHSKASEHALRWALEHQIFHADDIIVAYAIGE-TASAVLD------------HARKLLLSGETKEALVKATKQHHVDMLIIGSRGLGFLKRQLVGSTSDHCVNHCNCSVLVIRPK -> --TPRRVVVAVDESEESMHALTWCLSNVVSSAPKVVLVHARPADSADTVVAKARNICAAMS-PRVEARVEKGDPREVICGAAEEAGADMVVMGSHGYGFLQRTLLGSVSNHCVQHCKCPVLVVKRP -> --HGRNILIAIDHGPDSRRAFEWALFNLVRMADTIHLVHVLPA-KQKEAY-------------KTERHIIEGDPGKVLSHESARLEPAAVVMGCRGRSLVKSMLLGSVSEYCTRHCLCPVIIVPHK -> --SEKKVMVVMDENENSYHALMWVLDNLKESVSTLVIFAAQPLGRSLGLLEKAKSICASRGVN--ETLTEAGDAKETICNAVQKYKINLLVMGGQANRTFMRPFQGSLSNYCLKNAKCPVLVVKKP -> --DKRRIVIAYDGTEDARKLFDWSIKNIVNPNDHVILVSAQPR-AIRQVLS------------SSEQHILWGDPKETLPKYTQKNKVDLLIVGSRGLGSIKSVILGSVSDRCVHECPCPVLVVRNA -> --DLETIIVPVDGSGLGEEVIPHVAALASALNLKVTLLRATATAQAIDYMKGLEDKLHKQGV-AVDHRIIRGPADEVIVDLALETPDNMVAMTTHGRSGPARWTLGSVTDRVVRHSGDPVLVVRNG -> --IETRLVLPLDGTRFAETAIGPACELAASLQAKLHLLNVRGEDAPVTYLGDIRRQVNEKGL-SAVIGIRKGDIAEQIVSYACQNSADAIVMATHAPSELGWFLSGSTAAAVMRQSHLPVLMIPVH -> --GWPRLLLPLDMTDKAEAALNLSLELARRLRASLYLLKVNN--EANFYLEQIEKLAEEKGV-EVVKIVLVGNPETEIRSFADLFAPDALIMATHAAGTNGTSNPPSLTLEIMRRSHIPVFMVPLP -> --DGIRLLVPLDQTARSEAALEPAFDLAASLHAPVNLATVFLPPTASGYLHQVTHLAHAKGV-ETQAEVLMGDPYVRITEYAAQIEPDLIVMATHARGEVGRLIFGSVANKLLQNTHLPVLMVPAP -> --GALCTLVGLDGSRWAESALYPAAQLVSPQQGELHLVRVIQSLLAHEYLKNLVARLKDTSV-RLSWAIVKGSDAHTLLHLTATQLCHLVALATHGRGGFECWVMGSTAERVLAAATRPVLLVRPD -> --ICRNIVVPLDGSAMAETAVRVVEEMAEKLTGQEMTVNLLHVAQTEAYLRACGAELEKSGV-TVNHTVRTGKPEEVITAFTAESGAAMVVMACHARTGIGRYLIGSTADRILRTIEASVLLLRPG -> --PPKRVLVPLDGSERAAKVLPYATEYARLFDAELVLMRVCEQPQCSIYLQVVKDRISETGL-KVSAEALLGNAAEEIIGYIRQNRCDLVAMTTRGRSGMAHWVFSNVTEQVLAATSRGILLVRG- -> --PTKTLLVPLDGSDLAEEVIPHVEILAREESLEVVLLRVAETPSSIEYLERIEKQLKAKSI-AVKTVVVEGKANDEIINYANSNPYTMIVIASHGRSGISRLVYGSVAANLLNGVTCPIFMVKPK -> --PPQRVLVPLDGSDKAEKVLPYAVEYARLFDAELMLLRICEEPQCSLYLNEVEQRLKDSGI-KVTKESWLGNAAEEIIGYIKQNRCDLVAMTTYGRSAVPRWVFSNVTEQVLATTSRGILLVRP- -> --LPRTILLPLDGTPLAETAIPVASQFAQNTGATIYLIRVVEPGQAISYLERIRLRLQLAGV-SSCSRIAAGDPADVIARIVHAEDADLIVMSTHGRSGMERMVHGSVVSRIIGNTICPLLLMRGR -> --TLQRVLVPVDGSSLSLAVMPLASELCRALSATAVLLHVVALGEARQMLEELAEGLGRQGV-RAEVRVAVGHAINQIIQTAEELAPSIIVLSSHGRSGQGRPFMGSVAQAVLQRAPVPCLLAKPA -> --ALRSLLVPLDGSPPAEAILPWVKELARELKATLTLLRVDLDRAEQMYLAQIQKQLADEGI-RADTVVAVGDPVQEICRHVQEHDVDLLAMVTHGRTGLSLWLTGSVAEAALRSAPATLLLRRPG -> --ALRSIMVPLDGSAHSESALPYAVELARAFHADLWLVRVVESPVAESYLRIVLERLEGEGV-RGQYRLLTGFAEDELLAFAEDTEIDLVVMATRGRTGMERLTLRDLAGHLLRRGSAPVMMVRKA -> --RIGKIIVPLDGSTLSESALPFAISLASEIPSDLLITNVISPTDSDQYLFETTNKLSGNPA-TIESEVLEGEPSQAIMALVERHTDPLVILASHGRAGLSRLVMGSVTETLMRTSDFPILVIPEK -> --PLEHAVVPLDGLAEHEDALQAVIALMPVMVHGVSLLRVIASVEAERYLAAVSDRLVQQGI-QVTRRVVVGDPPTEIRAMI--SAGQLVVMVAHTRVHLIRWFDTLVDDAVEH-GAIDVLFMRSK -> --ILKKMLVPLDGSLESEAVIPYLSRIALSLNTSFTLFRVITGHSAEAYLRNWCQHLRKEGI-TAEYKVRAGAAAEQIIDYAGKRGFDLVAMSTRGQTGITRWALGSVAQKVLLGGNTPLLLIRA- -> --TFARALVMLDGSGVAEAALPMIEELTAHPITSVVLFRAITDSAATTYFLGVKERLTGSGL-QIELSVEVGDPTELIRHAS--EGVDVIVLATHGRGGFNRFRHGSVAERIVREADKPVLLVRAA -> --RIDTLMVCVDGSRPAESVLEPAVNLARRLDARLQLLHVVEVEMESGYVQSLARRIREAGF-EVEWEVLHGDSAEAIHRYLTPCTNAMVVMTTHGRSGFSQVATGSVSREILHKAHCPVGIMRPV -> --PEHPVMAAVDGSREAERGLELARETAEKLGARVALVRAYSVPAAAAYLKQIARAGE--------TYVVQGAPAAAIEAAANEADAGLVTVATRGLGLARRLILGSTTDRLMRTLRRPLLIVPPA -> --TLDKAMVMLDGSGVAEEALGITRELAGHPVQEVQFFEAVADPPATTYLMGVAERFAPSGV-KTTISVEMGDPSVLIEAAS--REVDLVILCTHGRGGFNRLRYGSVAESVVQNSTRPVLLVRAA -> -PMNTRLLVAVNGSEESYKALTHAVTIAEEFGSELKIVTVVPTQVYKKVLAKAEAKIRSEDM-NVNAILVEGRPSVKIVDLAEKERCDMIVVGRSPIGMILDWMEKSTSNIVLDDSKVNVMVVAH- -> --MYDTVLVPVDLAEKGYTVIEHALHVLS-PGGNLILLTALTGYTFDKAVKQVHQKLVPDAN-DCTTKVVEGKPVESILSVAKESNAQVIVMASHKQSRVGYMMLGSIANKVLSHSDIPVMVVKG- -> --MYKRVLVPVDDTEQSYCAVDVAGWLASASGGSVTLFHVRKPTKQKQIFRRCDKILSAYGV-KANAIAVDANIAGSITSECETGKYDAIVMGHRGRSQLKQLMLGSVANGVLVEAKCPTIMVHV- -> -----GYCEDPTRPSTHRRAVATALDLASRFDAAVHAVSVVDPERASSAADAVAEQ-APAPV-EVSTVVREGRPADAIVNYADEADADAVALGTRGRGGDEGFVLGSVAEAVVRTCERPVLTVRG- -> ----MKILLPLDGSVYSKKAINYLSHLEDIKKNTVFLVNVQKKIESRAILKPAKKKLEEAGY-KVKTKVCFGRATENIVKVSKEIKPDLIIMGSHGRTPVKGLLFGSKTSSVLASTKAPMLVLRK- -> ----MRILVPVDGTEQSRHMLRFLAGRETMLGPDITLANVQYSVEGRQVFDKLRDEISQLRA-DVKETVLYGDAGEAIAAEADRIDADLIMMGTRGLNAPMVYLLGSVSNSVLSKTQRPLLLVRP- -> ----MKILIPVDGSSYSKTALAFLASRRELLAPHIELLVAPEPLSAEDVLKPSREFLAKEKI-HAEEKFLTDEPAQAIVEEAKITAPDLIIMGSKNYGVHSGYFVGSVTGAVLSHTTEPVLVLRN- -> ----MRVLIPIDGGADCREAIRFVTSRKSWENPQIELLYVQKPYKIKAVFEDMAEDIATLPE-NVIKTSKIGHPAKVIASYARETGADLIVMGARGLSALKNLYLGSVSLGTIARATCPVLVCRE- -> ----MRILVPVDESLHSRRVIEFISHRETLLGPEIELVNVQYSVAGKKVFDELGPETLR-RR-GVTERVLYGDIGKTLAEEAEVFKADLIVMGTRGLNPVKGLLLGSVSNDLLARTKVPMLLLRD- -> ----MRVLMPVDGSSHNHAALAFLVGRRSWEAPDVELVHVRAPLAAEEVFAQLEHEAHF--P-TLTKKVLVGSPGLEIAQEAADTKADLIVVGARGHGFIDSMLVGSVSQAVIAKSDKPVLICHD- -> ----MKILIPIDASECSKNAAFWATGKPALFGPEIHIFYAQEPAEAKTVFDSIIDRCGTLPA-SVTLDYGVGSPVQTIVSAGDKLSADMVVMGTHGKGPLDSLLFGSVSNDVVAHSHRPILLIRE- -> --NLATIQVCCDLVSQTEPLFRWAVNLARPFGASLHCVHALEKPVQQTLLDRLHARLVQTDK-TIATAVVPGTAGDKMVAYAREHKVDLLIVGVKQHRGIQKRLIGSTTDTALRRAPCQVLTVPV- -> --CFGKIVTGCDVSAKAIPMLGYAMEVAAEFGAELHLLHAIERPVQQAMQDRLRQKLLEAPC-DLKAAVLQGVPGERLSSYAAENASDLIIIGKHQHTAIEKLLVGSTAEAVLRSDPCPVMVLSE- -> ---MQNIVLATDGSAYSDAAARCIADRKLFRDICVHVVHCLPDVESSKVMKSAIDILQGANV-QTLWHALVGFAPERIVAYATAVKAEAIVMGTHGRGAFLDAIVGSVASRVIAHAACPVVLVRA- -> ---MQSIVLAADGSTYSDAAAQCLAAGKLLKGLLVHLVHCMPDVESGRTLRSAAEILSAAGV-PFEQHALTGFAPERIVALARSVNAAAIVMGTHGRGAFLDAIVGSVAGRVIAHAPCPVILVKA- -> ---GRIVVLAVDGSDPAKKSFDWYLDNVHKEGDNVFIVTVGELARVETMLADYVDSLRAKRI-HGEGRQLTKNAGQAICDFAEKNGASLICMGTRGQGLVRRTMLGSVSDYIIHHSKCPCILVH-- -> ---TRKVMIAIDSSHHSEEALNFFFNNCYKPGEDFHVVHVISRPKANALKENYTSKLKALAQ-DEFVRGEVGGVGHTLCREAFDNEISLIVMSRRGVGVLRRTLMGSVSDYVLHHAHVPVMLVP-- -> ---EYLVLLGIDGSDHSVYAFEWYMHNFHKPGYKILLVHVPEISKIASMEAKYMDKMKGRGI-EGEFLRINEKPGPAIVECALEKEATYVVIGTRGQSKVRRTIMGSVSDYIVQHCHVPVLLFR-- -> ---TFKVLIAVDGSIHSEYAVEWYKAHIHDTEYSVVLAHVGEPEKVKNLLKKHSDHLKAGGV-E-IKCVAEGNAGVRLIEIAEKNKVQMIAIGTRGQGTVARTVLGSVSDYVLHHSSVPVCIIH-- -> ----MKVLISVDESKIAANAFDWYFEHIHQDGNEVIICHICEQPKLNSLKKAYETRMEGKNV-TAFLFNFAIPVGEAIIQIANKEQCDAIITGSRGMGAFRRTILGSVSDYVMHHAKATVMVCH-- -> --SLKSVLVASDFTEASSKPLRHAISIARHYHARFYLAHVVSSVDVTELERKLAERGDLAGL-SHEFIVRQGDVREELEAIIREKQAELVVIGTHGRHGIGKLVLGSVAEKIFREADGLVLTVGP- -> --KPSTILFATE-SPTHERAFAYALASAREYSAKLILFHAFDTLNEEKHLQPLLDRARGAGV-SAELAVRPGLAAPQILVYAREHAVDRIVMATRAPGRLGKLFIGSVAEEVLRSAPVPVVTIGP- -> --GLKTIVVATDLEGQADAALEYARKLATNYGARIVLAHGLDPMAARKVLDALAADL-LEGI-HSHSEIRQGTVAEMLVDVARQYEAGLIVIGTKGMEGVGPVVVGAIAEQLVRLAPCPVLAVAA- -> --RFQTILVATDFGESASAALQYAQALARAHRARIVITHVIDPAERQ-EIQTLEEET-RQGI-PVHSQVQTGMICDRILQSVKEMHADLLILGTRAKGKAGRAALGTVARQVLARTPCPVLTVSK- -> --NVEHILMATDFSDASRVAGAYAMALGLRFGSAIDAVHIYDPAMRQERLQIIERKM-LLGL-DAHAIHEGHPAAKKLLSLIEERHADLIVLGTSCRTGIDRLLLGSTAEAVLRETCHPVLTVGP- -> --EVKNILLTTDLTGTHKATLPFANALASRFDSKVHLLHVVTKVTYKTMVA--IMNGIDDNS-KKEILLRGGSFWQVVEKVIQENNIDLVVMGSHGRGGITRLLTGSTAEQVYRHATCPVLTVGP- -> --SPSQIILATDFSPASSAARSIAGRVARIFNAKILVVHVFQYVDVQQRMSETRKVLTDLGI-ETEGMLEDGFPSVEILNILQSYKNPLLVMGTHAVGGMDRFLLGSTAEEVLRQASCPVITTGP- -> -MDRKSVLVAFKNFKGDRSVLKEATRIARSNNAVVYLLNIVERSRAESEIEKAKDYLKSEGV-EALGLVKFGERSEIICDVAKKIKPVRIVIGNRGLRGIKRLLFGGVPERVVKTSPCPVYVVE-- -> -IKVNPILIIIKDLKNDKKVLKGGLERAIEEGRPAVIAKIIERPKAWQEVDKAIEEGEKLGI-NVYGVIKIGPLEEKINEVAKEVKAKLIVIGQKKISGFKKLVFGHSNKEENFEDTCPVLLIG-- -> -TKSKNVFVVLKDRKQNQTKLETRDYVATNNVEKIYLLKIIDRSRAENDISKFISELGKVNC-QVEGIIKIGSYQDRIEELSKQFNPEAIIVQSSKLSGIKKIFLGNTASDVINNAHCPVIIVG-- -> --MAKTILAAIRDSVSDRSVLNMAIDLARDEEAKLVICHVINRSKAEKTLSVAADIAKQRGL-DATKIVKLGKPSERIAELAKQLNATNIVLGNRKLKGIRQWLFSEFSTGFNNATLVPVEK---- -> -KTIKKIICPVDVYDFQPEAAEYAATLAKALDARIFVMHVMEPVEAEEKLAEIIAR--FGGDCQVDGEVILGRAADKILQVSEERAGDMVIMASHGRSFWGRAIHGSVTNRVIANAKIPVLVINP- -> -KPIKKIICPVDVYDFQPEAAEYALTLANALEAKILVVYVLEPVNAETKMAEVMSH--FCSICQDKGEVVVGYAADKILEIAKDRDGDIIVMASHCRSLVCRAVHGSVTNQVLANSNIPVLVVYP- -> --DYNSILVPFDDSVASRLALKKAFRFYNEYGSSIHVCYILPRYEGKKILSSAENMAKEAKI-PIELIMDEGSPAEKIVEIAERKKIDLLIIGPYGWKGLDRKLIGSTTEKILHLINIPVLIAK-- -> --MFERILVAIDGSANAWRALDHAVSLAKCMETGLGIVHVR---RSQALLHEA-EERVLQGV-RVARHAEEGSVVRQILVRRE--GYELLVMGSRGMGRAAGLILGSVSQSLVANLPCSVLIVDCR -> --MTRRIVLAVDGDTPQVQLIEWAAENLNIRPKKVHVTILYVTLQKRAELAAVNAAR----L-ELGIKTRPGDARDVVAVKAD--KTDLLVVGSRGLSGAAGMLMGSVSSYLVANAGCSVVVYRGA -> --MRSRIVVGVSPSLAGLQALRYAVKVARERGGTVDAVRVWLFRLIPH---AFDAAMGPTGV-KIEPVVLEGLTVQSLVEHAG--DDADLLVV-GGDRRGSLLGSGPVTRYSVRHARCPIVVVPPP -> --HRNTIVVGVDGSEPSVQALRWGFKEALLRDASVTAAIFWTPPVYREVLTEALRRARYEQV-PVLEVVEPGLAGARLVELAE--GGEMLVLGSHGHGHVMTALMGSVSAAVIRKANCPVVVIPTR -> --QRIHDCVGFDGSEHAQTALDWAVGEAGQRDGQLRLITAWNKA-YPAVLETAAKSAATATG-KVVEN---ESPASAILDAAE--DADPVVVGSRGHGGFPGLHLGSVTTQVINHAPCPVLVVRPK -> --QQAPVVIGYDGSVFAAHALRKGLAVASALGAPVRIVRAWTISAIREQLAEEVAAELHPDL-AVSLEVPHGAAGRELVNASH--DAQLVVVGTRGLGGFSGLLLGSVSDEVVEHAHCDVLVVRTR -> --QPAPIVVGVNGSVRSINGLRWAARQARLTGAEVQAVVGWEVPDARQVLDRAVAEVQEPDV-RITAHLIQKRAGLALTNAAE--GAQLLVVGSHSYSELPGVHLGSVASYCVHHASCPVVVIRGH -> --RKRKIVVGVDGSPQSEAALRWAVGEAAADRGEVRAVLVRARDLLRE---SVRKTLQENPP-LVEDLVADGDPATELIKESS--AADLLVVGSHGARMVTELLLGSVATQCVRHAHCPVVVLTAE -> --TGQAIVVGVDGSEQSRRALRWAVRQAEATGATVRAVIAWEPPIAEKVLAESVEKAVGSPV-EIRTVAAEGTAAQVLLTAAGAEDVVLLVVGSRGIGGFAGALLGSVGQHCAQHAPCPVVIVRGG -> ---MSGIMVGHDGSNHSQTALREALALAQGLGEEVTVVRAFGLRHVATALKRQIAPALFEDV-PVTVRAVPGKSAAVLIRESE--GFRMLVVASRGLGGLDKLLMGSVSERVVALAPVPVLVTRSR -> --ARNTVIVGVDGSPQSVSALRYAAQLSAKLDHDLVAFTSWLPRDARDALEATITEAFHVPA-QLGRQVIMGPAAPNLIEASK--SAALLVLGTRGRGGFKGLVMGSVSSSLAAHAKCPVLIHHGE -> --MGEHITVGVDGSAAGTAALEWALDEGIRSGYRVHVVTVCHPG-ELA---RAVETEIRPEA-SVWRRLLVGSPGPELVRVAS--DSVLLVVGSCGTGGLLATLLGSVSAHCVRHARCPVVVVPAG -> --MPQTVLVGVDGSDESVRALRWAANQVREVGGIVHAAMVWHQPRARKSLDAVVDGIKFPSV-DVRSRLVRGHVVDEMVALSK--QADLLVVGNKGHGAFTGMMVGSVALKLVHHAACPVVVVR-- -> --MTRSLAVGFDGSPDAARALRVGLALARDAGATTWVLHARGLLETVTELG--LDP-----A-SVRWRVEDGDPCSVLLGPPV--NAELLVVGRRGHGRHEGLLLGSTSLELVGHARVPVVVVPSP -> ----------MDNSRASAAALEWAMCQVRDG-GTVVAVSVCGMR-------RDAIARIREGV-RVEQSVLDGEPGPALVKLAE--QADSLVLGLHGYRRGGETVVGSVIVHCLKHASCPVVVVSSD -> --EGDGVLLATDGSSFSENAEKEAINMVSRCDYYICVVSAAANAEAKQRVQRIKTQAENKKI-TIETVTEIGSPCDMIVHKAREKKVDVIIVGSHGRTGLQRLLMGSVCAELIASSPCSVLITK-- -> --PNKSILTATDFSEYSKITLDMCLGAYRCMKTKLYVLHTIEKFG--QLEEDAIEDVMDK-G-DIIPMVRFGKPFLETIQVAKENSVDLLVIGTHGRAGVDRVMLGSVAEKIVRKADCPVMVIKS- -> ---MSTILFATDFSEASEVAGHVTRAVARHLQARVICAHA--VVFFQEDLAARHEELGRYL--SASSRMLDGSVIESICEAADEAQAALVILGSHGRTGLKRFVLGSVAERVVRLCSTSVLVARA- -> --KFQRIFAAIDFSSGSDEALRQAHERALSTWAKLAVCHIVPNEIDPFELERVAEVTGRTQA-EFDLIVDEGTPYAAILTHAEKWLADLIVAGSHGAAAAAGLRLGSVANKITQYAHCAVLIARP- -> --QLKRIIVGHDLGVGGEVALGSAVALANRCGAALRLVHVVEPLE--Q---KTGSPALAR-L-QVEYEVRMGKPFVELIIAGRAWLADLIVVGGASR--TEGPFLGSTSERILRKAMVPVMVTKK- -> --PVGPVVVATDLSDASRPAIERGGDHAAALGVPLIVCHVVPDVNGPDLIARAADVLGASAG-DARVTVESGAPDEEIVRIAEANRASLIAVGGKPREG-AQIVLGHVAERVVRYAHTSVLVARD- -> --ISPCLLLPTDFQQPARRAFKYGLAVARLLQTRLKLLHVIKLPY--MMRTSALRLAKDAGV-EAEPIVDFGVPDECILRRLRQERAKLLVMGTEGRTGWDRLRLGSTAQMLVRRADCPVLAVHG- -> --SNAAVWVASDFSSASDEAVRQADAWATRIGRPLVACHVLPELALDALREHVLTVTRRQPG-EFQTVVEVGQAPSALVRLAEREAMHLLVIGAEAGHG-----LGSTARRVMHYAPVSVLVARP- -> ---MIKIMVATDLSERSAHALQRAVQLIRQGGGEWTLVHVIDDDA--------ERLAEQAGS-KPRMIVASGDVAEVLVESAQGCSAELLVVGAHRKSSLRDFFVGTTLERVVRASHLPVLRVNG- -> ----RRVLIALDGSPGAQKAFNFWANAPGSRNDELILFSSLEMPLGLRVRRRAEVECRQRGL-RCKF-IDSSSPGAAIVEAAKRMGVNVVVVGCRGNNGIRRSILGSVSDYVLQHSARPIVVVPTK -> ----VKVLIAYDGSESSQRAVKYASKVLAQRDAEAIVVTAWESTQARDVHAEAKDLAAAAGF-TAHGELVSTTVWTALIAASDTFDVDVIVSGSRGVSGIRSLWHSSVSEHVLRGCKRPVMIVPSG -> ----VKVLIAYDGTESAQRAVKYASKVLAQRETEAVVVTAWESTQARDVHTEAKELARAAGF-TARGELVATTVWTAIIGASDAENVDVIVTGSRGTTGLKALWHSSVSEHVLRGCKRPVMIVPSG -> ----MSILIAYDGSSDAQHAIEETARLFPG--ASTVVLYARQPLLAHTTLDASEERARALGL-KAEPRVPEETAAEAIVDVAEEIDASLIVLGSRGRRGLPALLSGSTSTRVMHSTGRPTLIIPSG -> ----MTILIAYDGSDDARTAIEYAAAHVRTD-EPAVVLTVWEPLQTWYEQTEAEELARKAGF-GAVTARSNGPNWAAIVDVAESLDASLIVMGSRGLSGAKSVLLGSVSDRVLHHAHRAALIVPPV -> ----PRIIIAYDGSAHADRAVDHAAACLD--PAAAHVVTVWEPLRP-DARERAAARARQRGL-AAEALPSASAVWVALVEAAEATGADLIVCGTRGHGGLRGILTASTAEAVLRESGLPVLVVPPP -> ----PPALLCYDGSPGARRAIDVGGGLLGG--GPAVVLTVWQPVSLA-------TIGRASGI-SGEFD--EIAANAASDCAAQGVELAVIVLGSRGLSGVESALLGSVATGVLHHSHGPLLVVPPP -> ----PRLVVAYDFSDPARRAFELAVFMGRQLDAEVHVVTVLDSRK-----------AGTVQS-DDVKLHLGGEPADAIVAMAREIDAPLIICGTTGKGAVARTLLGSVSHELVHKSGAIVMSVP-- -> ----GTLLIAYDGSADAKTALEYAAKTFPG--REAVVLTVWEPLQGVSVEKGAAQLAIQLGL-KATARWGARSASETIDELADEIGAELIVTGSRGLTGLHSQDPDSASTAA-------------- -> --TYRRILLCYNATREGRCALRLGAALAHQLGAETHLLAVLDDASAKEILQEGVNKLAELGV-VAVGHLAIGNPMNQIPAFAQALKIDLIVVGHHRSGLLARWWTGQDDGRLLDRVSCSVLVAMD- -> --MGKVLLAAIDSSPQRRLVLDKAAEIGACMKAELHVVSVNDLSEIHTVLDEARDYLARMKM-DCRTHAPFGATAEQIALLAGELRADGIIIGHRHLSWLGRLVEGSVGSDLVARTPCDVLIVVE- -> --MYEKIILAFDGSHEARTALREGALLARRYGSRVWLLCVLSDSASATLVEEGLAKLKAFGL-EATGHVVRGDPAPIISAFARKVSADLVVVGHRKRSFLERWWSGSSGAYIVDDVDCSLLVARR- -> --PFSTILAAIDGGEQTAQVLDQALRLAEGPTATLHLVCVLDTLRARQTLREGLAHLARAGR-SGHAHVVVGAQAPAIIAEAERLGCDILVLGHRHMSLWRQMFGQSTCADVLEQAPCPLLIVTE- -> --MYKHIILAYDGSITGQKALLELKELAHWGQPRLTLVAVAPNPTLKEQLAQGVQALQDMGY-TV-GEVLKGEVIRELSRFAEHLEADLIVVGHKHENLLRRWWSGSTAKSLVEESPCNVLIVVD- -> --MYKRILLAYDGSEAGQKALLDCGDLAHLSGAALTLIAVMPLHRHQAVLDAGLARLRAAGH-HV-GEVVTGDSVTEITRRAKEIEADLIVVGHKHLNWAARWWQGAISGALIEHAHCSVLVSII- -> --QFKRILLPLDGSLLAERILLPTLKIIRGQEIELFMIQVVEKGKAKAYLAEVSEREMPPGV-VVHTHVEVGSAADVIVDFAKAEDIDLILVSSRGNTGFDSWMFGSVAEKVMKGAPCAIMVIRQE -> --QKIKMLVPLDGSKLAEGALKYVAVLCKQIGEDITLFRTIELFICIQYLQKMQKQLEKEGI-KSKYAVQDGIPADVIIDYSNKNDIDMIIMSTHGRTGLSRWAFGSIAEKVVQSAGSSVFLVRSS -> --LFRRILVPLDGSERSAAILPYITELTNKLESEVVLLRVVEMGSAQSYLDSVNSKLTGAKV-TVKSEVRVGDAAREIIRLAAETGCSLIAMSSHGYSGIEAGINGKVSKGITEGSSDDY-IGRVT -> --ILKKALVPLDGSPGSEAVIPYISEIAAKLQMELTLLQIASA-EIDKYLQDWCDHLGEEDI-AARYKVSAGSVADEIIDIADEFAFDLVAMSTRGKTAVNLWSLGSVAQKVFLGGNTPLLLVKQ- -> --KIKSIICAVDFSEESMKAVEFAASLVGQNEATLYLLNVVKPVESKERIEEIAKTLRNNGLDKVHGIVRTGEPVSSILNTIKEFKGDLIVMGNRKHGFRKGILFGSVSERVSADSPVSVLIDEI- -> --KIRRIIVAVDSSENSRKCAGFAASLANA-GCETIVLTVIKNS-TRRLHESLVVGSNMFKNKIRSEIVRADDISDAICKYCAETNADIVIVGRRGLGFLKGMLIGSVSEKVTRNCQCSVMIVK-- -> --MPQTILVPLDQELVIDSVFAAVKRVAGTEKARVILLTVIPEISARNQLERIARGQIDA-H-DWETDVRIGPVGRTIVRRADHFEADLIVMASHNPV-FWDVLLGSIAAQVVKHARHSVLVVRQ- -> --VFKSILVPVDHRSSWEHALPQALELAAAAKGTVTIMTVIRDMGAQSKLSAIISEQAKDGV-KITSEVRIGSIGREILSVAKDRTIDLILMASHRP-EMRDYLIGPNASFVAQHADCSVLVLRH- -> --MTLRILIPIDEKRSWTEILPELRLHAKGNSVELTCMTVVPDLVAQSRLGEITETE--EFG-IINRFARSGNIYSEVLQTADELSADLIILMSHIP-DFGDYWLGPNAAKIVRHANCSVLVVRP- -> --MYRSIIVPVDQPSSWRFALPQALALAEPGGARVALVTVVRELDAERKLAAIAAEAGAGGV-EIAREVRFGSIGHEVLACAAERRADLIVMESHRP-EMLDYLIGPNAAHVAQNAPCSVFVLRS- -> --MGDKILVPIDDQKTGLKTIAEGVIQATARKGELIVMTVVPDIEALEKLNEIVADHIPSGM-KVSTIARHGTAYEEILNVARDVGATMIVLGAHRP-SLKDYLIGPTAARVVRHAECSVNVLRD- -> --MAHKILLPIDHEEVLDEVFACAVEQAAMHDSTFVLLSVLPQLEAQRHLDRIGEERLTR-F-AWSAHVLIGHAGRMIVRAADDHEIDLIVMASHNPR-RMDVLLGSVADWVVRHARHSVFIVRQ- -> --KKPTVLVAIDQPE-QKAVLKRARQLADLEGIRLSVVTVLPDFESRVALHKFIEDTIGDDD-KVKHVIRVGKTYEEILITAEDLNAQMIVVGAHKPN-FRDYLIGPNAAQIARHAPCSVYIVR-- -> --MFKKILYPVDHVEFAAGFASEVERVAETFGAEIEVMTVMPGFEVERQLGEFASSAF---R-PVKIRVEQGTHWKRILSVAKEDAVDLVIMPHCDKG-WAEVLVGSCAQKVAERAPCSVLLLRP- -> --IFKNILIPIDDKKSIKGILSKALMLATNFQAKLHFMYVIPEFKYKAQIKELIKQYIPDEI-ETDYYIGSGAVYDEIIKHSNEIKADLIIISAVRL-QLKDYMLGPNASKIVRHSDISVLVVRD- -> --MYKCILVPVDHEHSWQSLLSASIDLARRHHAQLMVAFIDPNSRPNPFI----AEHIKN-I-RVPFQAEQGQIYSEILYIASVLNIGLIFMALHTPN-LANQLIGANAKKVVRHPQYSGMVCKK- -> --MHERILVPIKHAALSDESMMKALSIARARNAEIIALTVVPEIDSKPELEAFVKRHDDG-I-TISSVIRTGQPHRAIPRAAREFGCDLIVMNSHNPR-IRDYVIGSTAAHVVMHAECDVLVVRQ- -> --MIKSVLCAVEDKETDRLVLEQAAKLADLDGAQLDVVNVLPDFDTTARLKSVCAEILGEDA-KVRHVVATGTAYQEILKVAEAAGSDLIVIGAHKPD-LKDYLLGPNAARVTRHSECSVFVVRG- -> --MLNHLLLPIDHPSSWETALPTAISLARQNHARLTLLSVTPNFALHDRLQVFVENHLPADL-QSDFLVADGKVWEAILGSADKLGVDLIIMASHKRPKLERMLLGTNAMRVVQQAPQSVMIVRT- -> --MFSKILVPVDIAEETRKLLSRAKTLSDQWQSEVHVVSVIPNV---ETEAELARQIDAAGL-TATGHVLIGTVYDKVIALAKVLDVDLILIAAHQP-DLKDYLLGSNAARLVRHSERSVLVLRD- -> --MFDNILLTVDDPKSWEKALPQAVDMIRLSKGTLHILSVVPDMRAAKALEKLVEREVPDDV-KVKQHLKFGKIHREALKTIKKSNADLVVMGSEHPDSLREFLVGSNADRIVRRSPVSVLVVRA- -> --DTSLILCPVNHVQLNVTAYEEAKAMARRREAKLLVATIAPEMQLKSFVEQHPAEGI-----ELETVVRLGAVHRQIVKLADERNVDLIVMESANPR-VQDYLLGTTASHVVAHAKCSVYVVRG- -> --MFKSVLLTIDHPASWEKALPQAVEIVRASKGTLHVLSVVPDLAANTALNDLVTREVPQEI-NVKQHLAFGKIHDEVLAGIEETGCDLVVMASHQPDRVREFLVGSNADRVVRRSPVSVLVVRA- -> --MSKRFLCAIDHED-AKALLTEAGRLARLEGAALSVVTVLPDYSAQEALHQMERELLSDLA-PVQSIVVVGSAYEKVLEAAETVSADLVIVGAHKPD-FATRVIGPNAARITRYAQTSVLVVRL- -> --MFKNVLLAIDHKDEQNEAIEAAKKYAG-EGSHIFVVSVIPPLKAKEALHYFTKERMPEIK-DIKHLVVHGKVYEKITDIAEQLDIDLIITMASIKRDHQSSGFGPNVARIVRNSDCSVLILR-- -> --MFKDILLAIDDSSTWDRAAPKAVSLAKAFGADLHVMAVVPDFEANARLHAWVSENIPPGI-KVQHIVGHGRAYEEIMRIAGDIPCDLLILSARRTDEGDSYEVGPNTAHIVRHTNHSVLIVR-- -> --MYKNILIAIDNLDSAKYVVDTCLKLTD-NQAIFRVVTIIEP-EANKALHEFTEKAFK-GA-KVQHIVSYGTIYEEINHLADEKNVDLIVMLASSPN-A--KGLSANTVKVARNTDKPVLILR-- -> --MPENVLLPIDQTESWEMALTAARRQVD-EGGRIHLLGIVPDIAMKDGLDRFAKEHFPDGA-KVETHVGHGHVAETILKIAKKARADIIVMASPQRDELRSILISSHTNAVVRHSPCSVLVVR-- -> --MYNKILIVVDNIKRAEEIVRIAQDMTH-NNAVYRVATVIEP-EANKMLHEFTKANFK-GA-KVQHIVAHGSPHEEINRIAHDKSIDLILMFAKKDS-K--KGLDPSTVKIARDCEKPILLLR-- -> --MFGKVLLAIDEAQGSARAAKAALALTAQSGGEMHVVNVLPDSEAKTALRAFAGEHLPGMP-ERAMHIVQGTIYDRIIATANDIGADTIVVGSHRPE-FKDYLVGPNAARVVRHANQSVLVVR-- -> --MYNELLLAIDNPQGSQLVVETALHLTQ-NNARFRAVTVIEP-EVNKALHQFTQTHFP-SA-KVQHIVAHGTIYEEINRIAAEKQVDLVIMLASSPK-A--KGLSNNTRRVAKYGTTPVLIVK-- -> --MFKKVLLAIDDKEAHDKAFTVARQYAA--SELY-VVSVIPPVQAHAALCAFSDSKLG-LQ-NVHHMVAHGKVYEKITDIANELHIDLIITMASMQK-H--RAFGPNVARIVRNSDCSVIILR-- -> ---MAIILIPVDSSTHSEYCLDFYIKQLHREGNHVFSVYVGDYYKSAQIEEHVLQVLKENNI-TGTFKRVLKDVWHTIVEYSKTIKADMIVLGSRGMGKIRRTILGSVSESVLHHSHIPVLICKH- -> --------MPLDASSISSYCIHYYIEYIHKPENTVHVCFVANDFQCQMINAKVKDLFTTNGV-KFEFHRLTEDPWSIILNFRDEIEASLIVIGSRGQGALRRSIFGSVSDKVLKNSKVPVLVVKE- -> ---PRKILLAMDGSSHSEFAFEWYTTNLMKSDDQLVIVSALERHEHRILVNNLTKKLESTGL-KGMVKTQLGKAGEVVVKVASEEHVDHIICGSRGHSQIRRTLMGSHSDYILHHAHVPVTVCRH- -> ---SRVIAIAIDERDVAESAFQWYLDNLQRKDDFVVLIHILEYPKLDTVEERCKEHLQKLQI-K-KF-RTGGKSGPLIVDIAKQERATMIVMGSKGRGHTRRTLMGSVSDFVVHHSPIPVLVYRP- -> ---GLVVVLGVDQSEHSEYTLKWYLKHVHRSDHKLHLVHVPEHVQMTDIMNNYLQWCSQNGV-PDKFAHPNHEQWHEIIKYAEDVQAGLIVLGNKGQGKLRRTLLGSVSDSVVHHSPVPVLVCRN- -> ---QIKALIALDYDPSAKIIAEAAFGFAKSMGADVVLLHVISDPKSQHFLNHFKGHYGDKK---TETILCEGDFSTQILATAKDVHAGIIIMGSHSHNWFENVVLGSVTSQVVHESRIPVLVIPV- -> ---TTKILIALDYAPSAQQIAEQGYELSKQLHAEVIILHVIEDLEATVYLEKTKLHLQDKA---IKTKVVHGESVQAILEIASQLAVNYLVVGAHSKKSQDDMRVGHTTSHLLKHATMPIICIPT- -> ---MKRVLVAIDFLETTDKVINYAKKMIKESRGQLLIVHSETLEQLEDRLKEIHNNLSKDGI-KAEYVLMEGSTVDNILKEADIFKADLIVIGSHKHGKFHNLLFGSIHKSLIALSQIPVLIVPS- -> ---YKTILLALENNEKDFPIIAHVKELAFFLKAKVYLLHVMAGFN-KEKLMAVAKLFQEKGI-DTEIIIQYGDAASHIAEVSIEKKVDLIVMGSHCHGLVGSIFWGSTAIPVRKKAKAPILLIRS- -> ---MKKILIALDYNPNSEKVVEKGYELAKLMGAEICLFHVLSDVVAIDYLDKAKKHFGDSNEVIITTHLAEGDTAKEVLKYAESWGAHLIVMGTHSHSTLEKIFLGTVASSVLERTKVPVYMVPV- -> ---MKKICIXIDTSPSAEKVAKLGYEYAQALNAEVVLLHVIYDVETEIFLKATAEYLGNPS---IETKVLEGIADSEILDFVNTWGADLLVIGTHSHSFMENVLMGNIATKIVRHSKTPLLVVPI- -> ----MKILIAVDESLFTKKSFEFITTNSFKDIEELHLVHVIPDYQATELLEKNLGYINDMEVIKIPEILQGESIAQCLCQYCDTHEIDLVLIGCRGLSDYDSLSLGSVSHNLVNQSKISVLIVK-- -> ----NKILLAVDGSAYDEKSIAFINNKAAVRDIEVYVASVLPDIHTEKLLAHTVQK---LTVGKVFWNILEGDVAEQLLEFAEQTGIDLIVMGCRGLSNYEELVLGSVSMKVIRLSSRPVVIVK-- -> --MGHRILVPLDGTRLARSVLPWADLFAQALYAETELMRVVEPLDA---LASLRA-SEIHGR-AASIHVMRGEVSETIADRANALQVSLIIMASHSRAEPARTIIGSNVASVIHRSKVPVLVIRP- -> ---MGRIVVGVDGSDASKRALEWAAEEARLHGASLELVFVYHPPETDAIRQDAERVFATEVV-PVTLAVEDASPANALVDHSR--GADMLVVSARGMGAFRRLILGSVSSQLAHHAECPLVIIRGG -> ---MKKILVGIDGSQESINALKYAAKMAKLTGAEILGVNVINEPEYD--LAEAEDIVEMEGV-AIKTQVDVGSPDDVLAENGN--NVVMIVVGASGRGRGSRVFVGSKTHAIAAGLQCPIVVVPGN -> ----MRIAVAIDAARASARAMRTAVDEARAHGGGIDVIYVYREAAAGRDDRQARAALELDVV-EVRVVLTGANPARTLIERSS--QYDLMCVGSRRTGVFRDLRPSVVSELVARRAHCSVLISRGP -> ---IGTIVVGTDGSAGAERALHWAIEEASLRGTALQVVVAVDPSVTDDG-RAQARR----DA-EVSVGVHEGAPVDVLLSVAA--GAQLLVVGSHGTSSIRHNALGSVSDVLARVSPCPVVILPMG -> --MFKRILVPLDGSALAEQAIYHAEQFARIFGSKIILLQVLDPAKAEIYLEEVTKRMNDLLEDRVEYAISEGKTAESIVNFAHQENIDLLIISTHGAGGLSRWNISSITQKVIDMIYLPILLIRS- -> --DAAAIIACLDLSPHSQRVARLAAFLARETDRPLILFHAVSDERARRFLEEMAASI-NFPG-EIGIGIKEGQWQAGLAELCAMSGPATAVIGKSSVGDH-----VHLSASLLESGAGSLLVVPA- -> --VFRHVLACLDMSPFSHAVLAHASAVASMMNARLTVLHVLEPSDVEAALRDRMSRF--DGI-DAEIVLIDGPAAECICAWVRDHGVDLTVLGVSGNSNWPFPGLGGTARRVAEAIEGSVLLAPS- -> --VDGGVVACLDTSWLSHKVIPHAAAIAHALHASLTLLHVLEVASAHDYIRRLASER-DETF-HIDTIVVEGQPAEQICLWARNQKVGLIAVGTHGDSGAADWALGETARKLVETCSGALLLVPS- -> --MFARILVPLDGSALAEGSIPHAEMFARIFGSSLILLQVLDPTEADAYMQGIANRVRNLGENRVIYYVREGKAAENIIDFAHTENVDLLVICTHGLSGLSRWNISSVTHKVINLIYLPVLIVRA- -> --MFQRIVVPLDGSCLAEWVLPHAINLTKTLDIELVLIRVLQHEEAAAYLDAIASRLGALGL-HPETVTLEGEPADQIINFCRGDGHTLLAMTSHGIGGISHYMLGSVAHKSILQAHVSFLLVRA- -> --MFDPILVPLDGSQLAECVLPHAVAIARSFNAQVTLLRILEKNKASLYLEKTKMHFQEAGL-RAQVTVQEGLVAEGITEFAQGQRMKLIVLSSHGRNGATPWGMSSTSQKIILSAPTSIFIVRA- -> --MFSNILVYLDESY-DDGQLPYIASLAQHTRACMTILGHTQ--EAEIELDSMVQVLRDENIDILLDASEYASPAHALAHHARLINADLLIIGSSSRGLLLDPALTGAGIAI-------------- -> --MYRRILVPLDGSSNSEIIIPYVMAIAAHTPCEIVLATVAHPRQTEFLQHQINES--HKES-MVKNKVLQGKPAEEIVKYADEIEADLVAISSYGFSGQKPPLLGKISIRVLWNTKKPVLLVRS- -> ---MESLLVCIDFSPLTDRIVDTARGMAQCMSRGLHLVHVQPERKEVAMLAKLCKRLQDEGI-RTSCSTPAGRIDEMLTREAREHNAKMVIMGSHGNGAMYHLVVGSVAEGVLSNLGIPVVLVPAQ -> ---STKILICIDFSPLTPRIVKTGKELAKALNLGVHLVHAQPEKKEIKELNNLKSDFEEEDI-PCSYATPRGKTSDVIAAEAAKVEAPYIVLGSHGNGAMYHLVVGSVAEGVMKKLDTPVILVPAQ -> ---MINIVLPVDFGDKSDQLVDGAIQFAKQINGKICVIHVAPTDEELVMLNRVNQKILAHQI-ECEHILKQGIAKDLILEYAESKNADFIVMGSHGRSGIYDVFVGSLTKGITKSSKIPVLVLPI- -> ---MINIVLPVDFGDKTDQLIDGAVKFAKEVNGKICLIHVAPTDEELVLLNKLNQRILAQNV-DCEHILKQGIAKDIILEYADMKNAHYIVMGSHGRSGIYDVFVGSLTKGLTKSSKIPVLVLPI- -> --NIKKVMACVDLSDYSKMTIDYALSLVKGIDAEVLLLNVINNKTIDSYIEKINDLVNTTEM-KMPILIRAGVPYKEILRAVDKEKVDVVVLGNKGKTNLLGTLHGSHGEKVFRHSPVPVLSVRDR -> --SLSRIMVALDLSAYSESAFLHALTLAQSLGTELILLNIINSRGRDKYIQELEKEYLQVSA-R--LVFRVGLPYEQILKAVDKEQVDLLVMGTKGRTNIAGALFGTTAEKVFRRANCTVVSVRGP -> --KIKNMVVALDFSEYSGPILDYAVNIARQTQAGITVLHIINKKPYAEYVARLEAIVKHD-I-SLEIRVEEGIPSVEILKFLKNGDSDFLVIGQKGKSDLPEFIFGAVAEKVFRHSPVPVLSLRLQ -> --AIRKIVAGIDLSPFSSGILAYAGAISEGAGAEVIAVNVIDRNSSKRFLSDMRELLERH-V-PRSMKIRSGIPFTEVLRVVDEEEADLLVISAKGATNQKRHLLGGTCEKLFRHVPVSVLVLHS- -> ---INRILVSVDLSDTSKAVLNLAKAMSRRHQAELRLLHVITPETEVRRLHQWADSVLGHPM-PYSVECRTGTRTDRLVEAAHEIRADLIIMGAQRPEGLLKYVLGPETYHVIKQAPCPVLTVPEG -> ---IKNILVPTDFSNSAKNALEVGIALAKRHSAQLHILHVIIPQNDKNKLLETSKSIIKHKI-NVVNFIDIGIVSESIEKYASKLHIDLVVMGMNGMRGINEHFVGRNTFQVIKNAICPVFAIPEK -> ---IKNILVPVNFSEASNNALQTAIAMCKRHNATLHLVNVLETEAEEENLANMADAIQNHGL-SCRHYTEAGFIPYVICAKAEELDCDLVVTGTAGTK-VKKIMRVDNAMAILKNCSIPVLIVPSG -> ----MKILVPTDLSENADNALTFAVSYAQQQCASITLIFSYFAVNANSELQKIKER-LGNTV-DIDYKIIQGTVSTAIFSTANNGDFDLIIMGTQGASGIKKNLIGSNTATVIKESAIPVIAVPF- -> ----MKLLVGTDFSENAQNAMDFALQLAKAHNSSITLLFAYTPVQATKELKSLTKKCKKEGI-EIDYLIEQTTPSSAICSVADRESFDLIILGSQGKSDFPSKIFGSTTSEVIRLSSTPVLTVPA- -> ----KTIIAPVDFSDASTNALSFAAELSKRASARLIIVNVQADHKLKSVMSD-LKNAFGPGL-NCESLVTQGSLIAALTEITEAQRPNLIVMGTKGASGLKRILIGSNTVNVIANTKLPVLVIPE- -> -VMFRRILFPTDFSESSFRAFDCVKSFRKAGTEEVIILHVLDEYNARQKAEGMKNTLLESGI-NARIIIVKGVVDKEILSCAQRERASVIVMGRHSSDNLKEIILGTTSERVLKQARMPVLMINE- -> -FMFRKVLFPTDFSEGAYRAVEVFEKRNKMEVGEVILLHVIDEGEASRKLQEKAEEVKRRAK-NVRTIIRFGIPWDEIVKVAEEENVSLIILPSRGKLSLSHEFLGSTVMRVLRKTKKPVLIIKE- -> -PLFEKVLYSTDFSPLAEYAFHYVKRLKSAGMREVVIVHVVNELNVIERAEALEKELKNDGI-SVKLKIISSNAAGQIVKVAEEEKVNIIVIGAHGKGLLAQLILGSVSHDVVRKAKCPVLLVKK- -> -ESIKKILIMVDETPLSQNVVKCGYTLAKQLTAEVALLHVENSKQNMHYLENLSMKF-SDGV-QTKIFVMDGRIKESVLSAAREWNAQLIVAGTHERKGLGRLFKESVSEDILHSSPVPMLIVPE- -> -ELISKILIAVDGSASSEKIVEYGYNMARQIHARVGILMVEDSDVESDFLYRMKSMF-AKGT-PTELFLVKGPVRDVIFDTATAWGAQIIVAGIHHQTGISRFFVSSTADDLLHSTNIPIILVPL- -> -GNMKKIVIAVDNDPTSEKIALSGFQLGLQLKAEIALLSVVDLTDYKKNQQMLVDTV-FKEH-KIWTFVEEGIPYEVILNVAKEWDADIIVLGTHGRTGFSHLIMGSVAEKVIRHSEIPVFIIPT- -> --MYRKILIPVENSPNDQVILSHIQQLASLTGAKLILICVAHGWRDREYLMALCADLQNRGF-EAEYILAYGEPSDEIIKIAREHEVDLIAMTTHGHRFISDLLYGSVSHDVRHAVDIPVLLLRAK -> --MYETILVTLDGTPSDRAIIEHVKQLAKLANSRLVLLHVADGWEDTAYLRKVREEFQSTGI-PAEAELAYGEPADQIIKWVEQKGCDLVAMSTHGHRFLADMFLGATASRVRHSIGVPVLLLRAK -> --MYRKILVALDTGASDLELLPAVTALATLMQSELLLVHVADGWQDLSYLEATAAKLRAESL-TVNILLVLGEPPDQLLKVVAEERIDLIALASHGHRLIGDIIHGSTIDAVRHKATVPLFVVPPK -> --IYNRILVPIEGTETDAPVLEHVGRLAALCAAEVVLLRVAHYHDAERDLARAAEQLRSRGL-EVRTLLRSGEPQHVIVQQAEELVPDLIAMATHGHGWAKRMVLGSVADHVRHNTDVPLLLLKGR -> --RYRNILTAIDCSDADMTVIEHVSSLASEPGSVVHLLHVVHSHQAVTLLNGYREKMQADGI-DARVIIRSGEPEDEILSEIEENGYDLLAMATHGHRLPERILFGSVSRTLRKKITIPLLLINSD -> --VYREILVAIDCSPVDDFLVEQVSALALQLGATLHLLHVVHSHETTRILDQYRQKLEAEGI-GVRVVIRSGEPEQEILREIEERHYDLVAMAAHGHSLPERILFGSVSRTLRQNISIPLLLIKQD -> --PFSHILLLLDCSLVDHAIIPKIIDMSRCGNGRVTLAHVVHSHKADRFLDPVLKQFRDAGI-NAEKLLLSGEPEKELVKEIGEGDYDLVAMATHGHKTFSDILFGSVSDYLKHETDVPLLMVRGK -> -MEYRIILCPIKTPEISEKGVDAASYLSKLSGARLILLHVVENWEGSKLLNDAEVQARKTGLINVETVLKEGDIAHEIVAEAKKRRADIIVMSTVRHSTIERFFIGSVIDMVTKGAPCPVLWI--- -> --MFSRILVPIDLEAFSDGALRLAMKDVHDSAAELHLLTIVPGCAAIVELKRFADSRIPDSV-PVSLSVQDGAPAEQILKKARDMEADLIIMAAHNRGGIDGDEMGSTSSKVVAKARCSVVVLRAD -> --MITRILIPVEDLLFEEEI-REFLIQLSTLAIKLKVLHVIDA-ELVSTICENLKNYFP-GV-DVVSSVREGIVKEEIAKEAESFQADLILMGSHGRKGLGKFLLGSTAKDVIPLSPCSVVLLRTQ -> --MFKKILVPIDLEAFAEKSMRVAIQQANIHQAALHIITVIPGFTVRVKLEEYVHQNVPGEI-PVTFEVRQGKPHKGILKAAKKFRADLIIMPSHNYKRVEKALIGSCTSRVVAQARVSVMVIKPD -> --MFNKILVPVDIDKASKAVYDNAAELASLSGAQIRIVSVMPGFIFQKALDDFVAANCK-GA-NVSYKVLVGKHYEEILKMADKWGSDLIVVYHNRNRTVNEAFSSTCAQRVVKEANCSVLRLRNL -> --MFGKILVPVDLQEFSLNALKLALREIDDGATQLHLITVLPGFEVAQDLNDYAAKYVGAKI-KPILKVIEGSAPEEINRYVAKAGIDLVILRAHQRSKLNEFLLGSVSARVVERACCSVMVLKN- -> --MFRFILVPVDLNEFADKAVQHALWMAGKCEAKLHLITALPGIAVKSSLQTFAKEKIPESQ-AYSLSVEEGKPYKAIIKTADNLGCDLILMPSHKRSRGNKLLLGSNASKVLENAKVHVMILKH- -> --MFKKVIFPIDLEGSIEPHLKEIEKIIRYTQAELRVVTVLPGYIAAQELKNFMDQQLASDI-KLSSHIREGRPHEQILAEAKEWQADLIVMPSHIKSK-FSTHIGSVAQRVSERAKCSVLILRA- -> --MFKKILVPIDLADPATASLKVVKSMVEDMDAEVHILNVAPGYVIREELTKLAAEYLD--T-TPSVSIVTGKRAEKIIHFAEQWQADLIVIGCRAKARGSRHLLGSCSSQVADRAKCNVLVVR-- -> --MYQHILAPIDVSTIGEQILEKALFHLRYGNADITLLAVAPVKAIRSQLMAFAEHHIAAEG-RIHLKVSQGLPSDQVLKTATDIQAGAIFIGSHRGSQLGRPTLGSTAAKICSQAECDVVVVKAS -> --PMKNILVATDFSKQAHHAFEAALQLARRAGGSVTLLHVVETPETLKRLKATRQRMLAPGV-PVHDTAAVAEFPEAVARLIQERQIDLLVVGPQEHDTLERFFASTHTEQLIRQATCPVLAVKHA -> --RFKNVMLSTDFSSCSQHAKRYAYAFAKQPNGILHIAHSVEVTPLREIRSAAQEQLKVAGV-QTKGHLLEGYPPEKIDELALELGCDLLVVGTHGHSGLSHLVHGSTCSKILRSSPAPVLSVKEA -> ---MKNILVATDFSRQAHHAFEAALHLAQRAGGSVTLLHVIDAPEMLKRLEVTHQRMLAPGV-PVHETATVADFPEAIARLIQERQIDLLVVGPQEHDTLERFFASTHTEQLVRQAACPVLAVKHA -> -----------------------------SEQGKITILHVINREETNAYLTKVKNVVEKANL-AVEIVALEGFAATKILDFEKKNPVDFIVIGHHNRKGLDRIVVGSVSKKIIHDAACPVIVVK-- -> ---KRKCVVAVDGSKDSDYALDWFCKNVHREGDHVILVYVPEIHRIRSDLEVFADKLKIHGL-GGRVMSVMSKPGEGILKAAEDENAAMIVVGSRGKSTLRRTFVGSVSDYLVHHATIPVFVCKLI -> --DFKKILFATDLTNNCRHAFAYAANLATRYEGAITLLHVMESVDAHQALGTFSDTAQNERYVVENILVKDGHVVDTILETAQEEECDLIILGSNKTIFSDSKSLGSRTKSILKRSRIPVMMIPPA -> --EYNKILYTTDLSESGRYAFHHAASLTNRYGADLTVLHVVEGGEAKECVGQFCEEVQGNPDVSYRVVIKMGDPVNLIIEEAEAGNYDLIIMGSHGHGPLRTAMMGDTVLRVVKRSKIPVLVVRVP -> --PVTSILFATDLTANCQRAFDFTIDIATRLDATIYMLYVIEKLTARKAIHDFCKQEDMQDFTSREIIISHGDIVAEILSHSQKNECGLIVLGGHKNMFSKT-AVGSTAKRILKKSTIPVTMVPPE -> --FVSSILFATNLSENCIPAFELAVSLTKKYEARLVLLHVVEDMAARAALDQMCVNAGIDHRICKEVAIGHGDTVDAILVHAQKHGCDMIVLGAKAENQEGEVVVGKTIKGVLRATKIPALVVPAI -> --EFKTILFTSNLSETSRDAFCHATFLASKLKARIILLHVIEITKAGSALDQFCRDSDMDGIFDYEIVIKEGDVVETIIQQAAEHNCDMIIMGASEGILSG-ATLGGNVKAVLDKAKVPTLVVSMK -> --SIRKILYTTNLSETGRHAFAYAASLSKLYGSKLTVLHVVDEQEAGECVDRYCSELQDDAAISYDVMVKLGDPVKEIVKVAVEQNYDLIVVGRHRHSKFHDIVHRGTIRSLLDATRLPVFVVQIP -> --EINKILFVTDLTANAAHAYQYALTMAERFGAAIVVMHVMEGTEAQEALENFCTEVGQAKVTSDAIVITEGRVVDGIIDTCKKQDCDMIVMAHPVRRVIDEPLFGATTRGVLRKSIKPVLLVPPE -> --PLNAILFATDLTPNCQEAYEFAISQSLRFKAVVYILYIIEAMNALTDIHDFCEITGVGQFQPRELLISAGDIAETIIKNAQENKCDLIVLAARKGIMSRN-LIGNNIKSVLKQSPIPVTIVPTN -> --KVKKMIFATDLSMGARYAFKHAVDIAVHLNAVITVLHVIENIDAEKTLKQLCTNMQNEPSELVEIEVKYGDTAKLIIDQVENGNCDMIVLAYHYRNLIKEVLPGQVTRKVLKHAKIPILLIPIS -> ---MNKILIPIDFSENAERALAAAKIIAEKDTTQLLILHAYQPYEFQKKLERYIEDVVAEGY-QAEAIWAIGSVQSAVEEAIEAHNPDLIVIGRTGTGGFMDKLIGSSATSIGLHSTCPVLVIPPQ -> ---MKNILYPTDFSLTSRCSIPFLIEFANKTGASIHILNIFSVNSSKENLDLLKKELEGYNQTNLFTISRQGLVVDEILNYVEDNNIDIVVMGTTGASGILEKIIGSNAASVIEKCPKPVLAIPDK -> ---MKNILVATDFTENSRPALETAVYLASRQSATIHLLHTYLPVTYQEQIDKLTEELKARNV-IVTAYLELGPLTPVVKEFTEDKGVDLVIMGRTESGGWFSDLFGNSSTQLFDEIGVPLLVVPGE -> ---MKKIVVATDFQSSSEDAFAYATYLAEQFEAELALVHVYFPIIYETRLAETLASIPNKTL-KTSSKLIIGSVSSGVSGYAEEVGADLIVVGRNHESSFFERLIGSSASDIVKNTSIPVLIVPAA -> ---MRKILVPTDFSAIAANAFQFAQVVAERQNAEVDTMHAYHPSIKRELLDQFIEGNTRDSGSLPKPILNIGFASEE---IVRMKGYDLIIMGTTGEGNFLEKAFGSVSTHVARFAHCPVLLVPGN -> ---MNNILIATDFSDNSHKALQYAILVAKATQSAIYLVHTYLPRLYSK-MVPLASKVEEANI-KCHVVLEMNDVISGVFDTVEKYNIDLIVMGRTGSGGFLSKLIGSNAAHITAKAHIPVLTVPNQ -> ----MKILIGTDFSKASENAIEYTTQIARNFIAEVVLVHSYLPP--DEILEKKVRKLRESGV-RASYKVVIGDLRHAFEEVTKDEPADLIVLGKTENPDFLDKLIGSTSQHLLNQVQVPLLVVPEN -> ---MKTILVPTDFSKSANNALMFAKNLAVNHNYRIKLLHIVQ-TEAKEHNEALQKEIESAGIE-VESVTRRGLIESEILDELTQGNINLIIMGTKGVADLVDKLLGSNASSIIERASCPVLVVPSL -> --MLKNILYATDLGLFGPFVLEHVCELATKHNARVTVIHAVEPVTIRARVRQAFEEFIDMEC-IQDVLVLDGDACEVILETACSMDADLIVLGS-SGHSDHNTAIGSVASKVLQLSHIPIYLVPT- -> --NVRKILYATDMGENADIVFRYAISLTHRYNAHLTLVHVTEQLKMQSELEAFCINLKNSHL-VESITVIEGHSPQAIVDYAKTQEIDMIVMGT-EHTALGELFIGSVARRVTQLSAIPVLIVPI- -> --KINKILYASDIEKGSRPAFRAAISLCGKYESEITYLHVIEPLKIEQRISRFFEEVEFHIS-KVESRIEDGVSWETIIKVADEIDADVIVMGT-THSAMGQFFSGSTANKVMLNTKRPLLIIPL- -> --EINTIVYATTLGKNTRPVFRHAVNLARQYKARIIMVHALEPVTMQARVAKFRDELDGLGE-LDVQILVDENPAELVLRVAKTEQADLIVIGSSHHGLFGQKLLGDTAQQIGMHTKIPVLMVPN- -> --EVNTILYACDLEGQTQSALGHVMNLALAHQAKVVVMHVLEPLKMRVLLSDYINDKEAL-H-PPETKIAQGIPYEAIIHVAEKVEADIIVMNS-NHSRFGQMIIGSTANKVIHHSNIPVLVVPI- -> --DYKTILYASDLGKKTRPVFRTALSMARKYDAQIIMIHVVEPMTMKRRLARFCEEMDSHIN-VKEVLVVSGKTSEEILKAAEKYKVDLVIVGKSTRVILGNDVAGSTARRVSRYANIPVMIVPN- -> --KIRTILFACDLEPKTNQAMEMALNMAIANQAEIVLMHAIEPVRMQTYLGQFMEAAEEM-A-FPRLELAHGAPAEVIEATAEKVGADLIIMNS-THSRIGQMVIGSTANKVVHHSRVPVMVVPI- -> --TIKTILYVSDLKGGTWPSMRLACSIAQQYGAKMIYAHVVNHVRMKENVRKFLTDYPESPV-DIQIQVLEGYASQTILRTAELEHADLIVMSS-THGAIGQV-IGSTTNKVMHHGKFPVLVIPY- -> --QVKTILFACDLEDKTQESLALVMSLAVTQNAKIIFMHAIEPMAMETQITIFYENAAET-E-KPEYLIVQDDASSAIKHAIKDYQVDMVVMNS-THSKLGQMIIGSTANKVIHQSKVPVLVIPL- -> ------------MRPESKRVFRYAVSLAKQYDAKMLMLYVMEPLEIRQRVTRFYTELEALDV-QIDPLVVEGRHVASILEQAEAHNVDLIVMGN---------RSSQTVNRVVKKSKIPVTVVQM- -> ------MLWPTDLSPGSQAASAYVDMLASRFDAQVHLLYVATDFRIEEKINNICQNL--SGCPVQIKHIVTGDPAREILEAAETLKVDLIVMATQGSAG--PRFFGSTTEKVVRNAKIPVFTIKPG -> -MAYGTILWATDLSKNSLQAVGHVRELAEAHNARVVALYVGVDLQARHKLEAVCSKL--AACPNLSVRVLPGDPAGEILKAVTAEKADLVVMATRGASKAAGTGLGSVAAKVVAGSSVPVQFVNPN -> -MSVKTILWPTDLSRYSRESIDEVVSLSKLHNSKVVVLYSAIDLKARKTLNKLCDEL--RSCPLIEIRLTLGDPVTNIIEQAEKENADLIVISSHGKNNSAPDVIGSVAEQVIKKSPVSVHVIKNT -> -MNNPKVLWPTDFSRRAEKALPYIATLIREKKADVHILYVIPDISAAKRLNQLCNKL--DGCALFTRHTAVGEPADEILKLIDKEGMDMVVMAGHEPHI--PDIGEPTLEKVKRMASVPVEVIST- -> --DLKSILCPVDYSDPSKRALKNAIFLSAKLLARLTILAVFEPIRFENEMKEFIREFDLNGI-NHEIVIQTGIVDEKILQSIKEHGYGLLIMGTNGRSGLSRFFMGSITEKVIREVPCSFITTKT- -> --IPNRVLCPIDFSDESMLALDSAIHLCRLFESELHLIHAVKRIELEVELEDLTDQLDLNGI-TWSKSVILGDPAGAILDVIKNENIDLLMMASSGKGTLKRFFLGSVAERVSRKVPCSFIINKS- -> --MSQTILVPVDLTAVLDSVFAAVRRQINIEPTKVMLLNVVLGHYVERYTRHARNELTKR-ACEWHIDIELGPVARTIVRYADRVEADLIILASHNPL-VWDVFLGSTAAQVVKHARHSVLVVR-- -> --MYKKIIVPIAMDEHGESVLGIAVKLIDE-GGEIILLNVVEDLMIEESRKHAVKTLETHGI-NGRVEIRTGGAAGSINALAKEENADLVIIASHRPG-LIDYFIGSTASRVVSHCPCAVLIDR-- -> --MNRTILVPIDISELTQRVISHVEAEAKIDDAKVHFLTVIPSLYSAELPAMDDLKAEKF-ADRVQAHVAEGSPKDKILEMAKKLPADMVIIASHRPD-ITTYLLGSNAAAXXXXXXXXRAQIN-- -> --MYKTIVCAVGLGERAEHLVRTAYALLNT-GGILHVAHTVERFWAVSIISEAEEKMSKLVHVHVHVHVRTGRAADTILAIAAEMSADLIVVAAHTPD-VLDHVFGSTVDHIVHHAKCSVHIDR-- -> --MKNCILVPIDLAANFDLIFSATTTLARRHNAALHLLSVVPTEFVGEAQKLTESQLT---DISWTCEAVIGPIAQTIVRRAIDVGAGLIAIASHDPK-VRDLVLGGTADRVLRRARASVLVLH-- -> --MYDRVMCAIGLGERAEHLLRTSYALLKP-NGQLTVVHIVERFWAVSVIGEAEEKLNRLI------DVRTGTASKTLLIIAKERKADLIVLATHASD-ILDRIFGSTVEYVIRHAECSVLIDR-- -> --MYNSILVPIDISDLTRQVIPYVQAHSVLNTARVHFLTVVPTLYSAEMPKLKDFQHAKF-AEKIQTHAVSGAPKDQILNLAKAIDADLIIIASHRPD-ITTYLLGSNAAAVVRHASCPVLVVR-- -> --SLKHILMPVDLAELVEREVRMALKLLDDDGV-IDILFVDDTALTEK-HSATELAVHDV-QHRGRCIIRNGTVSDEVVAQAKKSNADAIVMASAKPK-FRSYLLGSNAAKIVRHATCSVFVVR-- -> --MYSRIIVPIAMDEHGEKILERAQSLLDE-GGEIILLNVVEDLLIEASREHAKKTLTEHGVTKGKVEIRIGGAAGIINTFAEEVEGDLVIIASHRPG-LIDYFIGSTASRVASHCKCAVLIDR-- -> --MYKKIIVPIAMDPQGEATLKRALSLLDA-GGEILMLNVVEDLMLDDSIRHAERTLDQYNV-PGRVLIEVGGASGRIMELAETEKADLVIIASHQPG-LSDYFIGSTASRVAAHCHSAVLIDR-- -> --MYDSIVIAAALFATTRAALEKAKTLLNP-GGAVTLVHVIEEVHMTTRHREVQEQLDAA-GIKVKAIIRHGQPSASILGAGKEANADLIMIASHKPG-LSDYFIGSTAARVVRHAQCSVLVTR-- -> --SKETVLVPVDVSHDRSRMFDEVAEHAG-RGAQVVLMTVVPEIMIKAMMDHAAIRLG-T-FEVADQIVRYGPVAPGIIDVAAETGATLIVINARSRD-RTAYLLGSVASRVANHARCSVHVVR-- -> --KYNNILVPVSFERNAAQALEIADAIRAS-GGRITVLHVLEQLHIDAARATVSGKLAEN-LPDAELVVVEGHSARSILDYAEEHAKDCIVLAGHRPG-MQDLLLGSTAARVVRQASCSVHVVR-- -> --MAKSILLPIDYSKSWEKALPVAREQAGFYGASLTILTVIPEIYGDGAAEHVKTKIKVQ-CDDLKVEIRQGSVYREILKYAHAEKIEMIVIASAEGD-FPNYEIGPNLARVVRNAHCSVLVIR-- -> --MYNKILVAMALDISP-QMLEIAQALCNP-GAEIVALHVFEAPAVRDGFDRARQLMAAH-IEGITARIVRGHTYRTLIDYSADHGVDCIVIGSHQPD-FSDYLLGSTAARVVRHAPCAVHVFR-- -> --MYDNILIPIVFDNDHSQAIECAKRLAGE-NPNITMLSVIELLATEERRVELQHEMDKG-VPGATCEIISGHPGRAIIDYANANGTNLIIVKSHRPG-FQDYFLGSTAAYVVRRAKCAVHVIR-- -> --MPEHILIPVALDNLARRKLDVARRLLDD-GGRITLLTVLEEIEANNLSENVRSRLRAD-AEDIGIDVISGKAGVRIPEYASKVGVDLIIVGSQKPG-ATGYFLGSTASRIVRRAECAVYVHR-- -> --MYKKILIALAPDDAAAELKAAARALAD-EGASILALSVIEIVIYEMPREDVERRLES--SPDILRRVEVGNPAATIRHVQETEGCDVVVLRSHSPA-LKDWVLGTTAGRVVRDVNCSIHVLR-- -> --MFKKILIPIAPDEALDESIGVARALAGP-DTTITALAVLEVIVYERSCKEVYETLKRD-QADVEIRAETGSPASKIVDVVRDEGFDLIVIRSHKPG-LQDWFLGSTAGRVVRHAPCSVHVVR-- -> -LLFENILFANDFSEYSERIWPILADMANHICAPVTLLHVREGRDNMRRLEDLVDSLSGGC-PKVDEEMAEGSPAPRILEIAAERNASLIVIGALGNRTVG-TLLGGVAERVLRESERPVLVLKA- -> -SLFDNILFPTDFSEGAERVIPYLCKITSEMKSPVTIFHVIAETTERFLLDAKRQRILKGCIQGISVELAWGNPGQQICTKAIEGIFSVVIMGSGGKGVTKEFFLGSIAKEVARHADVPVIFIPE- -> -QMSGHILYLTDFSSTAEKALNYVEKLVQETKCPVSILHVQNYEEIQTELQAIKNRLEKAGSTSVDFDFPEGRAIDVVIDIKNKPALSLVVMGSQGKGFVSELFMGSLSLQVTRYSPIPVMLIPA- -> -ELLSHLLFPTDFSQTAAEAMCYLELLAPRGVTRVTLLHALMTLVARNFLDLLQGRLEAAGVPEVETRMAVGHPVAVIVELVKTTDISLIVLGTQGKGFIAEISLGSVAHNISRFAPCPILLIPP- -> -NEMSHVLFPTDFSENAYHAFTYLEKMVEKGLKKVTLMHIQDIAIDRDRLDALRKRLEEKGDVEVEVVLEIGRPFREINRAIDEKHFDLVILGRQGKGIMMDLFIGSNSNNLARRAKTSVLLIPR- -> -RLFTSLLVPYDFSALSALALQKARDIAMVHGCPIRILHVNDNQFDEERLCKLRDALVAEG-LNASYELVEGVVLQEILKRSDPRDTSLIIMGNQGKGFLREAVLGSVANEVARQAEVPVLYVTA- -> -QAFDKILFATDFSQTAQRAGAFLKHILERPRATVNLLYVCDSGLDRQGLEALQRELAAPG-ATFKLECIIGKPAEEIIARTGNDGASLVVMGNHGKGFFREALLGSVANEVARRAEAPVLLVPS- -> -QMLSSVLVPIDVSESSDKLCALACGLAPRGVGRLEMLNVTPFTEAHRKLEALADRARGHGVRHVTTTVLRGQAAELVPERVGSGDYSLVVLAPRCRDVIE-REFGSVASAVLRASQIPLLLAPV- -> -HLFKRTLFATDFSENAERAFRSFEYLRH-ATKEVTLVHVESPKDPQDRLDDLADRLDELE-LDARTEIRRGDPADEILAAEAEHDPSTLMIGSRGRSRLRRLLLGSVSEEVVARATGNVFLVPP- -> -RLLSRVLFPTDLTAVSAMAANYLVRLAPHGLGTVDIVHVVDNTDAQERLAVLEGDLLAAGAAAVTTEVLVGSPERETARRCAMDGHSMIVMAPRCDEDPG-HPLGGVTHAVIQSTHTPVLLIPP- -> -RLLSRVLFPTDFTEASSIAAGYLEQLASHGLGTVNIVHVVDNTDAQEQLAIIAGKLLNAGAATVNTEVLVGSPERETARFCAASTPSMVVMAPRCNEDPG-QPLGGVTHAIIQTAHSPVLLIPP- -> -SLFARVLYAFDFSKQSEELLYYIKRFPI---DELIALHVAESE---DFIEKIKKE-----YPSAKIILKAGKVGKAIVDTAKDFNATLIAIGAGV------EKLGSVTTHVTRNSDVSVLVYK-- -> -KETNRIVIPVDKTEISRMAVEKGVDMAKLLGVDVAIISIDDSREHEAVLEELKKTAETKQV-NAKTEIVGDAPVDEIVKFIN--DDDLIVMATHQKKGLERFVLGSVSEEVLKRVNCNVMILKP- -> --VFANILLPLDGSLFSEACLKQVSDLARDFKSKLTLLVVIQPPQAQAYLERLTGELQANGI-ETEFRMVSDKIPETILSTAEDINASLISFTTHNRSGIEKWYYGSVAAGLIENSSHPMLLWRN- -> --KVERILVPLDGSLLAEEALPYARYLGQKTGAEVSIFHSKSS-ELTGYLDRIAAALAEQGA-KTKPVLRGSPPGLEIALEVEERDINLVVMSSHGETGATEGAFGSVASAVLHGSHVPVLIVPC- -> ---MHTILFPTDFSENAYQALVFALKIAAKQQAKLILMNAFPIPRSLEKLQALAKSIRFENL-DIDILSLPGDGVSVIKATARSQHADLIVMGAKGASGLQRFLFGNITADTILFSNIPVLTVPI- -> -MKRMRFLVPVDFSEGSGNAVRYAAALAETASSSVVVLHVVVPPEAQSKLGAWAA---DYNI-EVECKVRVGDVAEETRAMADLMNIDFIIMGTHSVTAVRKLLYGSHTTEVIERVACPVLAIPE- -> -IMYQKIVVALDGSESSRWALYEALQFAQLTQARLHAVYVVHPWDGRLALDEARRAMAERGV-PGDTEIAADDIPHCLARCVQRQGAGLVVMGTQGRHGIGRLLQGSVAETFLRGAHVPVLLVRCP -> --PISGILVPLDGAGIAASVLPTVASLARPIRAAVHLFAAVDLQRARAYLAALATPLQASGI-ESSYKAHAGDPMTDIVKLARRKHFGLIALSPHSRYAIGRGL-GSVTDRVLHSSPIPVLVTPPQ -> --LFQRILVPLDGSRLAEAILPAASGLAQACGGELLLLHALERQEASAYLEALARRLTELGL-AARSVVVQQAVADCIARLAAAFAADLVAMTTHGSGGLRGVLFGRIAQQVLQRAERPTLVQRSR -> --MFKDILLPLDGSKLSEASLDSARYIAKKLKSRITLLHIIEEDEAEEYLKSVARRIIPPGS-MIKVHVHVNDVAASIARHAEEYKSSLIIISSHGKSGIRDFLFGNIAQQIVGRGKTPLLIIKPN -> -DKIKIILAPTDLSEPSQAAVRYALNLARALGAEVTVYHVVNNEELARLLKSYQEHFS-DWV-RIREKVEMGVPEKSIVEWAEKEGSDLIVISMHERSDQTQASGSIVAEKIVRNAPCPVLSVHS- -> --AIKKIMVALAYSNYSAEEFAYASELATELNSDLVAANVINERDSEVYVKGLAEMIKASAFPRLTILFKVGNPVDELLKIIVVEKVDLVVMGIKGRTDLEYIFIGSVAEKLFQRSPVPIISFRD- -> --HINRILVATGFSGYAKGLTEYSAKLAANMNAELLVVSVINVRDGEHYAEGLRKILKKAGFPKVKVFIPTGHPVDEILNVALEERADLIVMGTKGRTDLSHVFVGSVADKVFRKSPVTVVSYRT- -> --EIRKLMVAIEFSENASELFDFAVGLASKLNSDLVAVNVINERSGENYVARLDSLIQETAFPRFKSIFKVGHPTETLIHVAVEEGADMIVAGIKAHTELEHFLVGSVAEKLFRHSPITLVSFRD- -> --HIKKVMVPVDFSEASKKGVNYGLSLALEFEARLVLANIVRYD-KAHLLDL----IPAELREDFELIVKSGDVRQELLGIVEEKEIDLVVMGSRGRSHVQRLLLGSVTERMLRKLHVPVLTVSH- -> --DIRKILVPVTFSEFSEELIGYAIDVARPLSAEVVFVNVIDQKDETQYIQELEERLSRINYPKMRIVFKRGRPAAVLLKFAIDERVDLIIMEVKGKSEILHALSGSIAEKIFRYSPVPVLSYRR- -> --AITRVAVAVNFADYSAELMEYVGDIAERNSAELLAINVIDKRSVENYVEDIEDLFHKTVPADTRAIIRMGIPFEQILKVVEEENIDMVVINSRGRSTFQDFMYGTASEKIFRHCPVPVLSLNL- -> --KVHTIMVAIDFSKYSQPTAEYAAQMAHDLDADLIFINIINQRQNDQFLTDLDGLIQSCHAERTRGLVRIGLPYQKLLESIDEEKPDLLIMATKGRTDLADVVMGSCARAMYRRSPIPLLSIRG- -> --KFRKVMVAFDRSEHSADALKYAAQLVKDLDAELSVVSVINQRSVEHYVSIIRKALANTAHAPFKSVFRIGVPFIELVQAIKDEGADLMVMGSKGRSNLAGVLFGTTAEKMFRRCPVPLLSIRE- -> --MLKKILVPVGFTKHSKGILQLAYDLAKPMSAKLLIANVVHERDGDHYIATLDEYVRDLGISIYDFVLLAGDPTTELLKTVLKEDIDLVVMGTKVK-DIKHIFIGSVAERMFRKCPVPV------ -> --PTNKVLVATDGSEVGICAAEYAANMAKELGVEVVAIGVINVHEVTGDLNKVREICEGKGV-HCKGIIGYGYPHEEIINYADRESVRMVVIGGSGKDFLGRKMLGSVAEKIVQELPCPVVVIPC- -> --KARSVAVAIDGSGPSWEAMTRAINMARLLELPLDVLTVIQIRYAKKMLVEAEERGKKAGV-KVQTHLLESGPSEAIVGWLGTRGIKFLVIGSYGHGFRGRHILGSTTERVIRELPVPVLVVPS- -> --ELKRIMVATDGSKAAEHAVRYAARLAKRRGTELVILHIVSYKAASKIVDAAEALVKEYEV-ACSRVIREALPHLAIVDVLERKDIWVLVLGDKGQDFEDRQTLGSTTHGVLHEIPVPLLVVPY- -> --PYQNIVVAVDFSLYSKHACKRAIELANYYQASLTLLNVVPEVAAQFQMKAFVNDLD-TDF-PIESKVICGEVNYSIVSFLEAQDVDLAIFGAKKKKGINK-LLGSVAHYVQNHSRCEILIVPV- -> --EIRSILFATDFSKDAERVEKIVGHWAGRLGAQVEVFHAIRETAAMRRSERVLDRLTQAGV-SCKSKIVYGRASDSILTRAESTGAQLIALGTSGYSAFQRFLLGSVAQRVSRHASCSVLVAGA- \ No newline at end of file diff --git a/esm/examples/P62593.fasta b/esm/examples/P62593.fasta deleted file mode 100644 index 07d7137..0000000 --- a/esm/examples/P62593.fasta +++ /dev/null @@ -1,10794 +0,0 @@ ->0|beta-lactamase_P20P|1.581033423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1|beta-lactamase_D207D|1.42563125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2|beta-lactamase_A215A|1.422813331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3|beta-lactamase_C75C|1.4155315119999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4|beta-lactamase_N134N|1.39696596 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5|beta-lactamase_L137L|1.355533136 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->6|beta-lactamase_L28L|1.3516090040000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->7|beta-lactamase_L199L|1.3516090040000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->8|beta-lactamase_F149F|1.32191175 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->9|beta-lactamase_A200A|1.295473865 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->10|beta-lactamase_E210E|1.29406548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->11|beta-lactamase_H24H|1.282201552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->12|beta-lactamase_L19L|1.280029666 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->13|beta-lactamase_A183A|1.279505214 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->14|beta-lactamase_T27T|1.248455477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->15|beta-lactamase_L38L|1.245034082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->16|beta-lactamase_I229I|1.23953749 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->17|beta-lactamase_R118R|1.23855076 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->18|beta-lactamase_V214V|1.238463943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->19|beta-lactamase_P143P|1.237482227 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->20|beta-lactamase_E175E|1.237061839 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->21|beta-lactamase_Y103Y|1.236680537 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->22|beta-lactamase_Q37Q|1.228947143 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->23|beta-lactamase_G142G|1.223102353 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->24|beta-lactamase_T126T|1.213890987 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->25|beta-lactamase_R63R|1.210016568 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->26|beta-lactamase_L223L|1.209258797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->27|beta-lactamase_K232K|1.204146451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->28|beta-lactamase_V117V|1.204146451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->29|beta-lactamase_A133A|1.204146451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->30|beta-lactamase_A170A|1.204146451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->31|beta-lactamase_G114G|1.204146451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->32|beta-lactamase_A123A|1.200392214 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->33|beta-lactamase_Q204Q|1.199645504 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->34|beta-lactamase_G234G|1.195860291 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->35|beta-lactamase_L146L|1.19545104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->36|beta-lactamase_V101V|1.195300092 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->37|beta-lactamase_G90G|1.189841882 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->38|beta-lactamase_P224P|1.189627145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->39|beta-lactamase_G154G|1.181999031 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->40|beta-lactamase_A225A|1.179258391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->41|beta-lactamase_T193T|1.16875245 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->42|beta-lactamase_T179T|1.167976192 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->43|beta-lactamase_I140I|1.165260346 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->44|beta-lactamase_A185A|1.165092705 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->45|beta-lactamase_D113D|1.158658061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->46|beta-lactamase_S128S|1.1574785159999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->47|beta-lactamase_E61E|1.15497924 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->48|beta-lactamase_A222A|1.154938626 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->49|beta-lactamase_P181P|1.153655812 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->50|beta-lactamase_A246A|1.150079227 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->51|beta-lactamase_R176R|1.149113002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->52|beta-lactamase_V29V|1.142534117 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->53|beta-lactamase_R189R|1.142419155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->54|beta-lactamase_F58N|1.142207789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESNRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->55|beta-lactamase_G43G|1.141336861 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->56|beta-lactamase_D155D|1.140947862 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->57|beta-lactamase_R92R|1.137335478 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->58|beta-lactamase_L49L|1.135457842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->59|beta-lactamase_P217P|1.13381469 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->60|beta-lactamase_A132A|1.132707897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->61|beta-lactamase_E56E|1.131946574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->62|beta-lactamase_A23A|1.126812329 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->63|beta-lactamase_L10L|1.123508365 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->64|beta-lactamase_T116T|1.122479724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->65|beta-lactamase_N173N|1.1186516640000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->66|beta-lactamase_G76G|1.117741507 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->67|beta-lactamase_H151H|1.112657025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->68|beta-lactamase_E166E|1.109622262 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->69|beta-lactamase_A182A|1.109467777 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->70|beta-lactamase_N168N|1.109437862 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->71|beta-lactamase_T112T|1.106795641 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->72|beta-lactamase_R220R|1.102208855 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->73|beta-lactamase_R273R|1.10144642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->74|beta-lactamase_G52G|1.100669144 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->75|beta-lactamase_F58F|1.100669144 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->76|beta-lactamase_Q88Q|1.100123891 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->77|beta-lactamase_L19W|1.094952121 -MSIQHFRVALIPFFAAFCWPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->78|beta-lactamase_T186T|1.0924468040000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->79|beta-lactamase_S122S|1.092373772 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->80|beta-lactamase_V8V|1.092009091 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->81|beta-lactamase_T178T|1.090003575 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->82|beta-lactamase_A40A|1.088883695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->83|beta-lactamase_D177D|1.086631569 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->84|beta-lactamase_D174D|1.084439673 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->85|beta-lactamase_V72V|1.082104419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->86|beta-lactamase_D83D|1.08160189 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->87|beta-lactamase_T139T|1.078124752 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->88|beta-lactamase_K190K|1.077426092 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->89|beta-lactamase_L205L|1.07521716 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->90|beta-lactamase_I45I|1.07460435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->91|beta-lactamase_A15Y|1.072458669 -MSIQHFRVALIPFFYAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->92|beta-lactamase_T187T|1.072082887 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->93|beta-lactamase_F64F|1.070829876 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->94|beta-lactamase_R202R|1.070247723 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->95|beta-lactamase_I171I|1.069139543 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->96|beta-lactamase_I244I|1.06740524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->97|beta-lactamase_A182M|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPMAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->98|beta-lactamase_S281F|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAFLIKHW ->99|beta-lactamase_V157K|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHKTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->100|beta-lactamase_A148M|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTMFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->101|beta-lactamase_T186C|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMACTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->102|beta-lactamase_T186W|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAWTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->103|beta-lactamase_S51D|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNDGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->104|beta-lactamase_L196N|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGENLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->105|beta-lactamase_N98Q|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQQDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->106|beta-lactamase_K109Y|1.067029036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEYHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->107|beta-lactamase_A16M|1.067029036 -MSIQHFRVALIPFFAMFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->108|beta-lactamase_L19Q|1.065112695 -MSIQHFRVALIPFFAAFCQPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->109|beta-lactamase_L19A|1.064585721 -MSIQHFRVALIPFFAAFCAPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->110|beta-lactamase_V8S|1.062300049 -MSIQHFRSALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->111|beta-lactamase_Y103W|1.0618851740000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEWSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->112|beta-lactamase_N50N|1.061565115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->113|beta-lactamase_T262Y|1.060920749 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTYGSQATMDERNRQIAEIGASLIKHW ->114|beta-lactamase_I206I|1.05990302 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->115|beta-lactamase_K190D|1.0596529609999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRDLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->116|beta-lactamase_F6F|1.059540238 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->117|beta-lactamase_T112Q|1.059511151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLQDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->118|beta-lactamase_P172P|1.05927624 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->119|beta-lactamase_P65P|1.058995065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->120|beta-lactamase_S122M|1.058884685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCMAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->121|beta-lactamase_A211D|1.058530502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEDDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->122|beta-lactamase_V29N|1.055182672 -MSIQHFRVALIPFFAAFCLPVFAHPETLNKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->123|beta-lactamase_Q274T|1.054812461 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRTIAEIGASLIKHW ->124|beta-lactamase_L196K|1.054812461 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEKLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->125|beta-lactamase_L19K|1.054812461 -MSIQHFRVALIPFFAAFCKPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->126|beta-lactamase_L160L|1.053874348 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->127|beta-lactamase_I171N|1.053548681 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEANPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->128|beta-lactamase_L199I|1.05306725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTIASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->129|beta-lactamase_Q97F|1.05306725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSFNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->130|beta-lactamase_Y44Y|1.052278813 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->131|beta-lactamase_C121C|1.0517263890000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->132|beta-lactamase_L19C|1.051597547 -MSIQHFRVALIPFFAAFCCPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->133|beta-lactamase_V29W|1.050740237 -MSIQHFRVALIPFFAAFCLPVFAHPETLWKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->134|beta-lactamase_L192L|1.050530784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->135|beta-lactamase_S233S|1.048897879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->136|beta-lactamase_Q97Y|1.048704173 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSYNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->137|beta-lactamase_F13M|1.048704173 -MSIQHFRVALIPMFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->138|beta-lactamase_V8Y|1.048113086 -MSIQHFRYALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->139|beta-lactamase_P60D|1.048065979 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRDEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->140|beta-lactamase_A280M|1.047482516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGMSLIKHW ->141|beta-lactamase_D33T|1.047482516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKTAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->142|beta-lactamase_L196Q|1.047482516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEQLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->143|beta-lactamase_A225M|1.047482516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPMGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->144|beta-lactamase_H156I|1.047482516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDIVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->145|beta-lactamase_H24N|1.047482516 -MSIQHFRVALIPFFAAFCLPVFANPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->146|beta-lactamase_L47L|1.04717842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->147|beta-lactamase_A15T|1.04666811 -MSIQHFRVALIPFFTAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->148|beta-lactamase_E237M|1.046260858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGMRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->149|beta-lactamase_H94I|1.045870416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIIYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->150|beta-lactamase_T193K|1.045310702 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLKGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->151|beta-lactamase_D36K|1.045310702 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEKQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->152|beta-lactamase_L199G|1.045310702 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTGASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->153|beta-lactamase_T186E|1.044739161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAETLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->154|beta-lactamase_K213A|1.044182477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADAVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->155|beta-lactamase_D33H|1.044033141 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKHAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->156|beta-lactamase_N152Q|1.043573211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHQMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->157|beta-lactamase_A16G|1.043573211 -MSIQHFRVALIPFFAGFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->158|beta-lactamase_L19T|1.043384099 -MSIQHFRVALIPFFAAFCTPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->159|beta-lactamase_R273K|1.042595885 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNKQIAEIGASLIKHW ->160|beta-lactamase_N98F|1.042595885 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQFDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->161|beta-lactamase_N173M|1.042595885 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPMDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->162|beta-lactamase_L19N|1.042595885 -MSIQHFRVALIPFFAAFCNPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->163|beta-lactamase_R202K|1.041897781 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASKQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->164|beta-lactamase_L196Y|1.041533532 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEYLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->165|beta-lactamase_T186M|1.04130992 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAMTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->166|beta-lactamase_D33Q|1.04115863 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKQAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->167|beta-lactamase_S122E|1.040966976 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCEAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->168|beta-lactamase_A182L|1.040374717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPLAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->169|beta-lactamase_L199C|1.040374717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTCASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->170|beta-lactamase_N152H|1.039881069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHHMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->171|beta-lactamase_T112K|1.039792035 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLKDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->172|beta-lactamase_N152D|1.039663907 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHDMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->173|beta-lactamase_A15C|1.039541742 -MSIQHFRVALIPFFCAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->174|beta-lactamase_G39E|1.039408923 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLEARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->175|beta-lactamase_D250Q|1.039105463 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPQGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->176|beta-lactamase_L19S|1.039105463 -MSIQHFRVALIPFFAAFCSPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->177|beta-lactamase_L199V|1.038836894 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTVASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->178|beta-lactamase_K30C|1.038523661 -MSIQHFRVALIPFFAAFCLPVFAHPETLVCVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->179|beta-lactamase_L19F|1.038424365 -MSIQHFRVALIPFFAAFCFPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->180|beta-lactamase_L19Y|1.038424365 -MSIQHFRVALIPFFAAFCYPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->181|beta-lactamase_Y260F|1.038284118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIFTTGSQATMDERNRQIAEIGASLIKHW ->182|beta-lactamase_R118W|1.038071257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVWELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->183|beta-lactamase_Q203Q|1.037941308 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->184|beta-lactamase_G194G|1.037941308 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->185|beta-lactamase_T261M|1.03791723 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTGSQATMDERNRQIAEIGASLIKHW ->186|beta-lactamase_R118H|1.037709255 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVHELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->187|beta-lactamase_T193V|1.036957496 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLVGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->188|beta-lactamase_T193Y|1.036957496 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLYGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->189|beta-lactamase_E102D|1.036957496 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVDYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->190|beta-lactamase_D33A|1.03674571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKAAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->191|beta-lactamase_P60A|1.036274052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRAEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->192|beta-lactamase_L49M|1.036166155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDMNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->193|beta-lactamase_K32Q|1.035932281 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVQDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->194|beta-lactamase_I171E|1.03545388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAEPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->195|beta-lactamase_T138V|1.035332007 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLVTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->196|beta-lactamase_D36G|1.035297703 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEGQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->197|beta-lactamase_V8K|1.03526594 -MSIQHFRKALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->198|beta-lactamase_P20Q|1.035116312 -MSIQHFRVALIPFFAAFCLQVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->199|beta-lactamase_A15G|1.034966585 -MSIQHFRVALIPFFGAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->200|beta-lactamase_A16S|1.034960526 -MSIQHFRVALIPFFASFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->201|beta-lactamase_D36R|1.034848817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAERQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->202|beta-lactamase_S104S|1.034734664 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->203|beta-lactamase_L19V|1.034685897 -MSIQHFRVALIPFFAAFCVPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->204|beta-lactamase_Q274W|1.034451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRWIAEIGASLIKHW ->205|beta-lactamase_V157D|1.034451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHDTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->206|beta-lactamase_I171H|1.034451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAHPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->207|beta-lactamase_I171Q|1.034451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAQPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->208|beta-lactamase_T193A|1.034451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLAGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->209|beta-lactamase_L196H|1.034451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEHLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->210|beta-lactamase_S2H|1.034451534 -MHIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->211|beta-lactamase_D129D|1.03412852 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->212|beta-lactamase_Q265S|1.033758317 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSSATMDERNRQIAEIGASLIKHW ->213|beta-lactamase_A200H|1.033433454 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLHSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->214|beta-lactamase_T139E|1.033328098 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTEIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->215|beta-lactamase_E237P|1.033244928 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGPRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->216|beta-lactamase_N50D|1.033198505 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLDSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->217|beta-lactamase_G141G|1.033150391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->218|beta-lactamase_A200N|1.033121785 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLNSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->219|beta-lactamase_T138R|1.033065197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLRTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->220|beta-lactamase_V8F|1.032822625 -MSIQHFRFALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->221|beta-lactamase_T138Q|1.032535194 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLQTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->222|beta-lactamase_Q97E|1.032535194 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSENDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->223|beta-lactamase_R118A|1.032220201 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->224|beta-lactamase_L196I|1.032124521 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEILTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->225|beta-lactamase_Q37Y|1.032124521 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDYLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->226|beta-lactamase_H94H|1.031828896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->227|beta-lactamase_L196R|1.031736718 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGERLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->228|beta-lactamase_L196T|1.031678958 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGETLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->229|beta-lactamase_T112Y|1.031489943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLYDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->230|beta-lactamase_F22E|1.031489943 -MSIQHFRVALIPFFAAFCLPVEAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->231|beta-lactamase_S122D|1.031193716 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCDAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->232|beta-lactamase_R202Q|1.030773368 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASQQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->233|beta-lactamase_A280E|1.030728313 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGESLIKHW ->234|beta-lactamase_A225Q|1.030728313 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPQGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->235|beta-lactamase_T138N|1.030663419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLNTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->236|beta-lactamase_A15S|1.030447527 -MSIQHFRVALIPFFSAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->237|beta-lactamase_S122L|1.03037931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCLAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->238|beta-lactamase_A15F|1.03037931 -MSIQHFRVALIPFFFAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->239|beta-lactamase_I54P|1.03022069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKPLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->240|beta-lactamase_I171A|1.030202219 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAAPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->241|beta-lactamase_L199P|1.030148857 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->242|beta-lactamase_F58Y|1.029797606 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESYRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->243|beta-lactamase_G194T|1.029660682 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTTELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->244|beta-lactamase_I54V|1.029660682 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKVLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->245|beta-lactamase_P60G|1.029564904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRGEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->246|beta-lactamase_D207A|1.029526984 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIAWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->247|beta-lactamase_E102Q|1.029439611 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVQYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->248|beta-lactamase_K284E|1.029239064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIEHW ->249|beta-lactamase_A182I|1.029197039 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPIAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->250|beta-lactamase_R41K|1.029197039 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAKVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->251|beta-lactamase_T138K|1.029132731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLKTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->252|beta-lactamase_T186F|1.029021902 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAFTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->253|beta-lactamase_Q265K|1.029021902 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSKATMDERNRQIAEIGASLIKHW ->254|beta-lactamase_R118Y|1.028889474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVYELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->255|beta-lactamase_N173W|1.028785878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPWDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->256|beta-lactamase_T193S|1.028450362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLSGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->257|beta-lactamase_H24A|1.028343247 -MSIQHFRVALIPFFAAFCLPVFAAPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->258|beta-lactamase_L19I|1.028223427 -MSIQHFRVALIPFFAAFCIPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->259|beta-lactamase_M180Q|1.027935995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTQPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->260|beta-lactamase_H156K|1.027935995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDKVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->261|beta-lactamase_N50M|1.027935995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLMSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->262|beta-lactamase_S122N|1.02762071 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCNAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->263|beta-lactamase_Q97R|1.027307281 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSRNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->264|beta-lactamase_S68S|1.027290257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->265|beta-lactamase_Q274L|1.027164396 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRLIAEIGASLIKHW ->266|beta-lactamase_W163F|1.027047508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRFEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->267|beta-lactamase_A182V|1.027009197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->268|beta-lactamase_H285T|1.026864943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKTW ->269|beta-lactamase_L192I|1.026786171 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLITGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->270|beta-lactamase_D207S|1.026786171 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLISWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->271|beta-lactamase_T112W|1.026786171 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLWDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->272|beta-lactamase_A15M|1.026726945 -MSIQHFRVALIPFFMAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->273|beta-lactamase_T138A|1.026521413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLATIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->274|beta-lactamase_A200D|1.02651594 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLDSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->275|beta-lactamase_R41H|1.026505776 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAHVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->276|beta-lactamase_H151W|1.026307086 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLWNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->277|beta-lactamase_R118N|1.026307086 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVNELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->278|beta-lactamase_T112E|1.026307086 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLEDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->279|beta-lactamase_V29G|1.026236327 -MSIQHFRVALIPFFAAFCLPVFAHPETLGKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->280|beta-lactamase_M180S|1.025999814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTSPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->281|beta-lactamase_S201H|1.02587843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAHRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->282|beta-lactamase_N152E|1.02587843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHEMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->283|beta-lactamase_A222C|1.02568062 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSCLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->284|beta-lactamase_D269E|1.025616898 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMEERNRQIAEIGASLIKHW ->285|beta-lactamase_N98T|1.025616898 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQTDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->286|beta-lactamase_A246M|1.025566761 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAMLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->287|beta-lactamase_K30T|1.025566761 -MSIQHFRVALIPFFAAFCLPVFAHPETLVTVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->288|beta-lactamase_Q37K|1.025566761 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->289|beta-lactamase_Q97V|1.025313927 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSVNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->290|beta-lactamase_T138E|1.025143677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLETIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->291|beta-lactamase_Q37N|1.025143677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDNLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->292|beta-lactamase_A222R|1.02502112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSRLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->293|beta-lactamase_T193N|1.02486983 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLNGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->294|beta-lactamase_D36A|1.02486983 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEAQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->295|beta-lactamase_T112R|1.02486983 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLRDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->296|beta-lactamase_Q86S|1.024853997 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGSEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->297|beta-lactamase_I283Y|1.0246168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLYKHW ->298|beta-lactamase_E145N|1.024536562 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKNLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->299|beta-lactamase_Q37V|1.024536562 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDVLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->300|beta-lactamase_N152R|1.024536562 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHRMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->301|beta-lactamase_E145G|1.024461014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->302|beta-lactamase_T112L|1.024427688 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLLDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->303|beta-lactamase_A182F|1.024271022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPFAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->304|beta-lactamase_H151K|1.024271022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLKNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->305|beta-lactamase_F22H|1.024271022 -MSIQHFRVALIPFFAAFCLPVHAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->306|beta-lactamase_M180E|1.024122078 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTEPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->307|beta-lactamase_E237S|1.024122078 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGSRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->308|beta-lactamase_H285F|1.024026691 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKFW ->309|beta-lactamase_V21C|1.023990823 -MSIQHFRVALIPFFAAFCLPCFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->310|beta-lactamase_N98L|1.023844908 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQLDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->311|beta-lactamase_T131G|1.023770338 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNGAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->312|beta-lactamase_A16V|1.023747469 -MSIQHFRVALIPFFAVFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->313|beta-lactamase_E46E|1.0235926990000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->314|beta-lactamase_L55M|1.023592367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIMESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->315|beta-lactamase_D33R|1.023592367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKRAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->316|beta-lactamase_Q203E|1.023592367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASREQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->317|beta-lactamase_L199E|1.023592367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTEASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->318|beta-lactamase_G90E|1.023445573 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLERRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->319|beta-lactamase_L196S|1.023445573 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGESLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->320|beta-lactamase_R118E|1.023425244 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVEELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->321|beta-lactamase_S281A|1.023282066 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAALIKHW ->322|beta-lactamase_D36L|1.023217856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAELQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->323|beta-lactamase_R238N|1.023217856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGENGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->324|beta-lactamase_T193G|1.022816663 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLGGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->325|beta-lactamase_T193R|1.02274395 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLRGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->326|beta-lactamase_I171M|1.02260517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAMPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->327|beta-lactamase_G90K|1.02260517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLKRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->328|beta-lactamase_G39K|1.02260517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLKARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->329|beta-lactamase_K32M|1.02260517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVMDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->330|beta-lactamase_H156A|1.02260517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDAVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->331|beta-lactamase_F17V|1.02260517 -MSIQHFRVALIPFFAAVCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->332|beta-lactamase_L19H|1.02260517 -MSIQHFRVALIPFFAAFCHPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->333|beta-lactamase_H24K|1.022449287 -MSIQHFRVALIPFFAAFCLPVFAKPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->334|beta-lactamase_S254Q|1.022375303 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPQRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->335|beta-lactamase_S80Y|1.022251183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLYRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->336|beta-lactamase_L196A|1.0222349590000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEALTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->337|beta-lactamase_A9S|1.0222349590000002 -MSIQHFRVSLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->338|beta-lactamase_A225P|1.022082496 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPPGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->339|beta-lactamase_L192M|1.021921726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLMTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->340|beta-lactamase_M153C|1.021921726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNCGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->341|beta-lactamase_M153W|1.021921726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNWGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->342|beta-lactamase_I206Y|1.021921726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLYDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->343|beta-lactamase_E61G|1.021921726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPGERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->344|beta-lactamase_H5M|1.021921726 -MSIQMFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->345|beta-lactamase_R189Y|1.021653157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLYKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->346|beta-lactamase_A15W|1.021572039 -MSIQHFRVALIPFFWAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->347|beta-lactamase_A148R|1.021532848 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTRFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->348|beta-lactamase_A222K|1.021420455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSKLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->349|beta-lactamase_N50G|1.021420455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLGSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->350|beta-lactamase_K144E|1.021420455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPEELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->351|beta-lactamase_K144S|1.021323211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPSELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->352|beta-lactamase_A280Q|1.021037246 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGQSLIKHW ->353|beta-lactamase_D33Y|1.021037246 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKYAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->354|beta-lactamase_R118S|1.021037246 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVSELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->355|beta-lactamase_T112D|1.021037246 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLDDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->356|beta-lactamase_N98E|1.021037246 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQEDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->357|beta-lactamase_H24T|1.021037246 -MSIQHFRVALIPFFAAFCLPVFATPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->358|beta-lactamase_G251N|1.020877551 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDNKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->359|beta-lactamase_N173L|1.020877551 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPLDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->360|beta-lactamase_S281V|1.0207346659999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAVLIKHW ->361|beta-lactamase_A280K|1.0207346659999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGKSLIKHW ->362|beta-lactamase_I171V|1.0207346659999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAVPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->363|beta-lactamase_M180T|1.020668696 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->364|beta-lactamase_T186L|1.020623642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMALTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->365|beta-lactamase_E108E|1.02057291 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->366|beta-lactamase_M67A|1.0205349 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMASTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->367|beta-lactamase_E61H|1.0205349 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPHERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->368|beta-lactamase_I171L|1.020527277 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEALPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->369|beta-lactamase_T139A|1.020489748 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTAIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->370|beta-lactamase_H24V|1.020287344 -MSIQHFRVALIPFFAAFCLPVFAVPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->371|beta-lactamase_P20D|1.020287344 -MSIQHFRVALIPFFAAFCLDVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->372|beta-lactamase_E166W|1.020227531 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPWLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->373|beta-lactamase_R41R|1.020220409 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->374|beta-lactamase_N152Y|1.020117387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHYMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->375|beta-lactamase_E166Y|1.020066663 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPYLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->376|beta-lactamase_R92V|1.020031968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRVIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->377|beta-lactamase_A225N|1.020018384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPNGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->378|beta-lactamase_R118G|1.020006753 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->379|beta-lactamase_I206L|1.019972645 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLLDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->380|beta-lactamase_E210I|1.019972645 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMIADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->381|beta-lactamase_A148S|1.019953685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTSFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->382|beta-lactamase_S254A|1.019928958 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPARIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->383|beta-lactamase_Q37A|1.019907946 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDALGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->384|beta-lactamase_L247M|1.019739064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAMGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->385|beta-lactamase_E270D|1.019739064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDDRNRQIAEIGASLIKHW ->386|beta-lactamase_D36W|1.019739064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEWQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->387|beta-lactamase_E237G|1.01965257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->388|beta-lactamase_D36T|1.019558943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAETQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->389|beta-lactamase_N173Q|1.019558943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPQDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->390|beta-lactamase_L196E|1.019415764 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEELTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->391|beta-lactamase_Q97M|1.019354584 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSMNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->392|beta-lactamase_V21A|1.019326241 -MSIQHFRVALIPFFAAFCLPAFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->393|beta-lactamase_S57A|1.019273368 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEAFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->394|beta-lactamase_A148N|1.019140061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTNFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->395|beta-lactamase_A9T|1.019005287 -MSIQHFRVTLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->396|beta-lactamase_K53T|1.018920358 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGTILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->397|beta-lactamase_D250N|1.018870905 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPNGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->398|beta-lactamase_Q88H|1.018829857 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEHLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->399|beta-lactamase_T186I|1.018646511 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAITLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->400|beta-lactamase_E166S|1.018550538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPSLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->401|beta-lactamase_K190E|1.018499717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRELLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->402|beta-lactamase_E237A|1.018484177 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGARGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->403|beta-lactamase_E175P|1.018448505 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDPRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->404|beta-lactamase_E175V|1.018424951 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDVRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->405|beta-lactamase_L47I|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEIDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->406|beta-lactamase_E46S|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYISLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->407|beta-lactamase_S281Y|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAYLIKHW ->408|beta-lactamase_Q204M|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQMLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->409|beta-lactamase_V101T|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLTEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->410|beta-lactamase_G251H|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDHKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->411|beta-lactamase_R202T|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASTQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->412|beta-lactamase_D33C|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKCAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->413|beta-lactamase_E119Q|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRQLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->414|beta-lactamase_V29Q|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLQKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->415|beta-lactamase_D36F|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEFQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->416|beta-lactamase_T138H|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLHTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->417|beta-lactamase_A225K|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPKGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->418|beta-lactamase_Q37D|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDDLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->419|beta-lactamase_L199N|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTNASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->420|beta-lactamase_H156G|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDGVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->421|beta-lactamase_E102P|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVPYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->422|beta-lactamase_N98R|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQRDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->423|beta-lactamase_K109M|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEMHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->424|beta-lactamase_K144D|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPDELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->425|beta-lactamase_E195N|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGNLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->426|beta-lactamase_Q265G|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSGATMDERNRQIAEIGASLIKHW ->427|beta-lactamase_Q265H|1.018162735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSHATMDERNRQIAEIGASLIKHW ->428|beta-lactamase_A16L|1.018162735 -MSIQHFRVALIPFFALFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->429|beta-lactamase_S2I|1.018162735 -MIIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->430|beta-lactamase_A200S|1.017789689 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLSSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->431|beta-lactamase_R238H|1.017609568 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEHGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->432|beta-lactamase_E175M|1.017587871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDMRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->433|beta-lactamase_V8T|1.017474502 -MSIQHFRTALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->434|beta-lactamase_A200Q|1.017433356 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLQSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->435|beta-lactamase_K53N|1.017387031 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGNILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->436|beta-lactamase_N173D|1.017374521 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPDDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->437|beta-lactamase_R189Q|1.017334451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLQKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->438|beta-lactamase_K144A|1.017257828 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPAELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->439|beta-lactamase_I45V|1.017240725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYVELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->440|beta-lactamase_V106I|1.017223036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPITEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->441|beta-lactamase_R238M|1.017123055 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEMGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->442|beta-lactamase_T186V|1.017060506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAVTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->443|beta-lactamase_E166D|1.017060506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPDLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->444|beta-lactamase_H156Y|1.0170263000000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDYVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->445|beta-lactamase_D36I|1.016909705 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEIQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->446|beta-lactamase_A9P|1.016841976 -MSIQHFRVPLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->447|beta-lactamase_S2N|1.016766527 -MNIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->448|beta-lactamase_A148D|1.016731538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTDFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->449|beta-lactamase_A23G|1.016725479 -MSIQHFRVALIPFFAAFCLPVFGHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->450|beta-lactamase_A211A|1.016651251 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->451|beta-lactamase_S281E|1.016586405 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAELIKHW ->452|beta-lactamase_A182R|1.016522879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPRAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->453|beta-lactamase_Q265A|1.016417523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSAATMDERNRQIAEIGASLIKHW ->454|beta-lactamase_G194S|1.016374912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTSELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->455|beta-lactamase_E237N|1.0163528240000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGNRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->456|beta-lactamase_A148E|1.016318716 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTEFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->457|beta-lactamase_V8N|1.016283239 -MSIQHFRNALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->458|beta-lactamase_M66V|1.016275225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPVMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->459|beta-lactamase_M184I|1.0162463940000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAIATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->460|beta-lactamase_A182Y|1.016208082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPYAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->461|beta-lactamase_S254K|1.016154525 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPKRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->462|beta-lactamase_E61Q|1.016126671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPQERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->463|beta-lactamase_K144N|1.016126671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPNELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->464|beta-lactamase_D33V|1.016038125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKVAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->465|beta-lactamase_A84N|1.016038125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDNGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->466|beta-lactamase_N98A|1.016038125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQADLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->467|beta-lactamase_K252E|1.015705737 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGEPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->468|beta-lactamase_A211Q|1.015590803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEQDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->469|beta-lactamase_I171W|1.015590803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAWPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->470|beta-lactamase_S51T|1.015590803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNTGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->471|beta-lactamase_Q203M|1.015590803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRMQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->472|beta-lactamase_A9Y|1.015590803 -MSIQHFRVYLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->473|beta-lactamase_V106L|1.015521315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPLTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->474|beta-lactamase_E61M|1.015497273 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPMERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->475|beta-lactamase_Q265L|1.015447918 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSLATMDERNRQIAEIGASLIKHW ->476|beta-lactamase_K144G|1.015335721 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPGELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->477|beta-lactamase_L49F|1.015288223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDFNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->478|beta-lactamase_A280I|1.015288223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGISLIKHW ->479|beta-lactamase_Q203H|1.015288223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRHQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->480|beta-lactamase_D250H|1.015288223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPHGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->481|beta-lactamase_E166F|1.015170944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPFLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->482|beta-lactamase_N152S|1.015170944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHSMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->483|beta-lactamase_Q203R|1.015123251 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRRQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->484|beta-lactamase_V29A|1.015108591 -MSIQHFRVALIPFFAAFCLPVFAHPETLAKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->485|beta-lactamase_H156D|1.015108591 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDDVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->486|beta-lactamase_K284T|1.01508103 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLITHW ->487|beta-lactamase_N98S|1.015069889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQSDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->488|beta-lactamase_E175T|1.015065588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDTRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->489|beta-lactamase_S281T|1.0150245409999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGATLIKHW ->490|beta-lactamase_A182K|1.014975772 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPKAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->491|beta-lactamase_R238C|1.014920455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGECGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->492|beta-lactamase_T27V|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPEVLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->493|beta-lactamase_S254C|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPCRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->494|beta-lactamase_E210V|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMVADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->495|beta-lactamase_D36V|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEVQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->496|beta-lactamase_E26L|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPLTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->497|beta-lactamase_N50P|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLPSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->498|beta-lactamase_E195H|1.014905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGHLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->499|beta-lactamase_E61D|1.014805522 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPDERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->500|beta-lactamase_A266L|1.014792621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQLTMDERNRQIAEIGASLIKHW ->501|beta-lactamase_Q204E|1.014792621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQELIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->502|beta-lactamase_Q86V|1.014792621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGVEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->503|beta-lactamase_P12I|1.014707496 -MSIQHFRVALIIFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->504|beta-lactamase_R176K|1.014672312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEKDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->505|beta-lactamase_K284D|1.014672312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIDHW ->506|beta-lactamase_N152T|1.014587187 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHTMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->507|beta-lactamase_A15L|1.014543012 -MSIQHFRVALIPFFLAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->508|beta-lactamase_M180C|1.014497762 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTCPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->509|beta-lactamase_V42F|1.014403743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARFGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->510|beta-lactamase_S281K|1.014403743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAKLIKHW ->511|beta-lactamase_A222Q|1.014403743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSQLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->512|beta-lactamase_P217K|1.014403743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGKLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->513|beta-lactamase_N50E|1.014403743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLESGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->514|beta-lactamase_V8C|1.014403743 -MSIQHFRCALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->515|beta-lactamase_I206M|1.014304838 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->516|beta-lactamase_A246L|1.01425343 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIALLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->517|beta-lactamase_K190T|1.014200557 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRTLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->518|beta-lactamase_L219I|1.014173681 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLIRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->519|beta-lactamase_R92I|1.014157262 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRIIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->520|beta-lactamase_F22W|1.01409051 -MSIQHFRVALIPFFAAFCLPVWAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->521|beta-lactamase_F149W|1.013974208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAWLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->522|beta-lactamase_Q204L|1.013974208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQLLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->523|beta-lactamase_E237Q|1.013876183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGQRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->524|beta-lactamase_I3N|1.013819107 -MSNQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->525|beta-lactamase_Q86I|1.013773563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGIEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->526|beta-lactamase_E145A|1.013760369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKALTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->527|beta-lactamase_T193M|1.013720299 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLMGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->528|beta-lactamase_D207E|1.013720299 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIEWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->529|beta-lactamase_D36C|1.013720299 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAECQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->530|beta-lactamase_I3K|1.013720299 -MSKQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->531|beta-lactamase_Q4E|1.013720299 -MSIEHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->532|beta-lactamase_S96S|1.01359188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->533|beta-lactamase_K190N|1.0135815190000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRNLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->534|beta-lactamase_N98K|1.013508806 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQKDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->535|beta-lactamase_D207Y|1.013433747 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIYWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->536|beta-lactamase_T186R|1.013395338 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMARTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->537|beta-lactamase_T112I|1.013276104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLIDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->538|beta-lactamase_K252H|1.013276104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGHPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->539|beta-lactamase_Q4N|1.013276104 -MSINHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->540|beta-lactamase_S254T|1.013176417 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPTRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->541|beta-lactamase_A225T|1.013072527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPTGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->542|beta-lactamase_S96N|1.013018872 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYNQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->543|beta-lactamase_A15V|1.012988673 -MSIQHFRVALIPFFVAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->544|beta-lactamase_T267P|1.012944009 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAPMDERNRQIAEIGASLIKHW ->545|beta-lactamase_N173E|1.0129271009999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPEDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->546|beta-lactamase_L47V|1.012900225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEVDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->547|beta-lactamase_N173G|1.012889376 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPGDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->548|beta-lactamase_M180K|1.0128798959999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTKPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->549|beta-lactamase_G90D|1.0128639659999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLDRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->550|beta-lactamase_K109R|1.01284569 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTERHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->551|beta-lactamase_P217A|1.012840706 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGALLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->552|beta-lactamase_A230C|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFICDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->553|beta-lactamase_T262H|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTHGSQATMDERNRQIAEIGASLIKHW ->554|beta-lactamase_V106E|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPETEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->555|beta-lactamase_A211R|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMERDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->556|beta-lactamase_I171K|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAKPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->557|beta-lactamase_D33K|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKKAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->558|beta-lactamase_P217M|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGMLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->559|beta-lactamase_A200E|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLESRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->560|beta-lactamase_V29I|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLIKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->561|beta-lactamase_H151A|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLANMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->562|beta-lactamase_Q37L|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDLLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->563|beta-lactamase_N98H|1.012733102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQHDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->564|beta-lactamase_R7Q|1.012733102 -MSIQHFQVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->565|beta-lactamase_L100L|1.012592475 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->566|beta-lactamase_T112S|1.012578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLSDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->567|beta-lactamase_E270T|1.012524345 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDTRNRQIAEIGASLIKHW ->568|beta-lactamase_P12M|1.0124805609999998 -MSIQHFRVALIMFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->569|beta-lactamase_D250E|1.012473817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPEGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->570|beta-lactamase_I171G|1.012375889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAGPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->571|beta-lactamase_E26T|1.012298778 -MSIQHFRVALIPFFAAFCLPVFAHPTTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->572|beta-lactamase_E108V|1.012298778 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTVKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->573|beta-lactamase_T186A|1.012265061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAATLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->574|beta-lactamase_I171T|1.012239552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEATPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->575|beta-lactamase_E145K|1.012239552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKKLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->576|beta-lactamase_K53A|1.012225674 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGAILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->577|beta-lactamase_K109S|1.012225674 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTESHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->578|beta-lactamase_K213Q|1.012203391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADQVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->579|beta-lactamase_S80K|1.012179154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLKRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->580|beta-lactamase_D99E|1.012179154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNELVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->581|beta-lactamase_L73I|1.012054447 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVILCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->582|beta-lactamase_F58W|1.012054447 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESWRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->583|beta-lactamase_A225H|1.012054447 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPHGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->584|beta-lactamase_Q265E|1.012054447 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSEATMDERNRQIAEIGASLIKHW ->585|beta-lactamase_F22C|1.012054447 -MSIQHFRVALIPFFAAFCLPVCAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->586|beta-lactamase_K144R|1.012032555 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPRELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->587|beta-lactamase_I3P|1.011708669 -MSPQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->588|beta-lactamase_R189K|1.011647195 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLKKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->589|beta-lactamase_A225E|1.011598622 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPEGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->590|beta-lactamase_A276S|1.011559138 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQISEIGASLIKHW ->591|beta-lactamase_A222S|1.011516918 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSSLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->592|beta-lactamase_H156N|1.011455639 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDNVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->593|beta-lactamase_K53I|1.0113966090000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGIILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->594|beta-lactamase_L135I|1.011375792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANILLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->595|beta-lactamase_T186G|1.011321452 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAGTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->596|beta-lactamase_E175Q|1.011316761 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDQRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->597|beta-lactamase_E166L|1.011275518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPLLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->598|beta-lactamase_E175A|1.011275518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDARDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->599|beta-lactamase_Q204C|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQCLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->600|beta-lactamase_V157Q|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHQTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->601|beta-lactamase_A148L|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTLFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->602|beta-lactamase_A280D|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGDSLIKHW ->603|beta-lactamase_G39A|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLAARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->604|beta-lactamase_T193H|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLHGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->605|beta-lactamase_I54L|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKLLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->606|beta-lactamase_D113T|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTTGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->607|beta-lactamase_Q37F|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDFLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->608|beta-lactamase_L199Q|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTQASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->609|beta-lactamase_H94M|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIMYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->610|beta-lactamase_K109G|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEGHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->611|beta-lactamase_K284Y|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIYHW ->612|beta-lactamase_N173R|1.011181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPRDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->613|beta-lactamase_P20K|1.011181792 -MSIQHFRVALIPFFAAFCLKVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->614|beta-lactamase_H151R|1.011054935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->615|beta-lactamase_Y95F|1.011011542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHFSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->616|beta-lactamase_K190R|1.01099571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRRLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->617|beta-lactamase_A200G|1.010918403 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLGSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->618|beta-lactamase_H94T|1.010905405 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRITYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->619|beta-lactamase_P60E|1.010758708 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFREEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->620|beta-lactamase_D269A|1.010716487 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMAERNRQIAEIGASLIKHW ->621|beta-lactamase_D33I|1.010644849 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKIAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->622|beta-lactamase_D113E|1.010644849 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTEGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->623|beta-lactamase_E175D|1.010520143 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDDRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->624|beta-lactamase_E61Y|1.010509001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPYERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->625|beta-lactamase_A185G|1.010447039 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMGTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->626|beta-lactamase_T267D|1.010388595 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQADMDERNRQIAEIGASLIKHW ->627|beta-lactamase_E175H|1.010344126 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDHRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->628|beta-lactamase_A225D|1.010309236 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPDGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->629|beta-lactamase_D207G|1.010281089 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIGWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->630|beta-lactamase_H94V|1.010251085 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIVYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->631|beta-lactamase_Q203K|1.010207789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRKQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->632|beta-lactamase_L10T|1.010166448 -MSIQHFRVATIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->633|beta-lactamase_H285N|1.010121491 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKNW ->634|beta-lactamase_A148G|1.010061875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTGFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->635|beta-lactamase_A211E|1.010018384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEEDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->636|beta-lactamase_E169S|1.010018384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNSAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->637|beta-lactamase_V29D|1.010018384 -MSIQHFRVALIPFFAAFCLPVFAHPETLDKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->638|beta-lactamase_V29E|1.010018384 -MSIQHFRVALIPFFAAFCLPVFAHPETLEKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->639|beta-lactamase_T112P|1.010018384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLPDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->640|beta-lactamase_A16C|1.010018384 -MSIQHFRVALIPFFACFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->641|beta-lactamase_K252V|1.009971276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGVPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->642|beta-lactamase_Q88A|1.009906773 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEALGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->643|beta-lactamase_L160V|1.00986465 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRVDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->644|beta-lactamase_L191M|1.009819693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKMLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->645|beta-lactamase_L111V|1.009819693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHVTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->646|beta-lactamase_R81K|1.009819693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSKVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->647|beta-lactamase_N173C|1.009819693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPCDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->648|beta-lactamase_Q97P|1.009650518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSPNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->649|beta-lactamase_N50T|1.009644752 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLTSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->650|beta-lactamase_E166M|1.009630483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPMLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->651|beta-lactamase_I206A|1.009539298 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLADWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->652|beta-lactamase_V8H|1.009539298 -MSIQHFRHALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->653|beta-lactamase_R238F|1.009492875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEFGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->654|beta-lactamase_G76A|1.009475381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCAAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->655|beta-lactamase_A280S|1.009475381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGSSLIKHW ->656|beta-lactamase_I206V|1.009460526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLVDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->657|beta-lactamase_Q97K|1.009460526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->658|beta-lactamase_D250S|1.009451828 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPSGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->659|beta-lactamase_E175I|1.009303958 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDIRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->660|beta-lactamase_I171C|1.009277961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEACPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->661|beta-lactamase_N173A|1.009277961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPADERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->662|beta-lactamase_A170V|1.009219029 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->663|beta-lactamase_Q265T|1.009215412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSTATMDERNRQIAEIGASLIKHW ->664|beta-lactamase_A148Q|1.009187265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTQFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->665|beta-lactamase_E169W|1.00911338 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNWAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->666|beta-lactamase_N98I|1.009052101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQIDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->667|beta-lactamase_Q37E|1.009000303 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDELGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->668|beta-lactamase_T138T|1.008987895 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->669|beta-lactamase_N98Y|1.008917719 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQYDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->670|beta-lactamase_A84T|1.008884294 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDTGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->671|beta-lactamase_H24G|1.008884294 -MSIQHFRVALIPFFAAFCLPVFAGPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->672|beta-lactamase_M153S|1.008765354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNSGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->673|beta-lactamase_G251K|1.008660975 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDKKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->674|beta-lactamase_Q97L|1.0085909990000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSLNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->675|beta-lactamase_I171R|1.008564025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEARPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->676|beta-lactamase_D36E|1.008522488 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEEQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->677|beta-lactamase_A222T|1.008460037 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSTLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->678|beta-lactamase_F70M|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTMKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->679|beta-lactamase_A222N|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSNLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->680|beta-lactamase_V157N|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHNTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->681|beta-lactamase_A211H|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEHDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->682|beta-lactamase_A211N|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMENDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->683|beta-lactamase_A280V|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGVSLIKHW ->684|beta-lactamase_D33N|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKNAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->685|beta-lactamase_T193E|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLEGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->686|beta-lactamase_L196C|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGECLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->687|beta-lactamase_E26I|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPITLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->688|beta-lactamase_K32A|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVADAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->689|beta-lactamase_K32R|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVRDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->690|beta-lactamase_Q37M|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDMLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->691|beta-lactamase_T112H|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLHDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->692|beta-lactamase_H94Y|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIYYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->693|beta-lactamase_K213M|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADMVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->694|beta-lactamase_R273E|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNEQIAEIGASLIKHW ->695|beta-lactamase_N152A|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHAMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->696|beta-lactamase_K284R|1.008389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIRHW ->697|beta-lactamase_A9M|1.008389474 -MSIQHFRVMLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->698|beta-lactamase_C18T|1.008389474 -MSIQHFRVALIPFFAAFTLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->699|beta-lactamase_L19G|1.008389474 -MSIQHFRVALIPFFAAFCGPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->700|beta-lactamase_Q4H|1.008389474 -MSIHHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->701|beta-lactamase_R7T|1.008389474 -MSIQHFTVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->702|beta-lactamase_S2L|1.008389474 -MLIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->703|beta-lactamase_Q86A|1.008173485 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGAEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->704|beta-lactamase_H24S|1.008138888 -MSIQHFRVALIPFFAAFCLPVFASPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->705|beta-lactamase_A266C|1.008020631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQCTMDERNRQIAEIGASLIKHW ->706|beta-lactamase_A148T|1.007989161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTTFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->707|beta-lactamase_K109A|1.007982222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEAHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->708|beta-lactamase_K284S|1.007825655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLISHW ->709|beta-lactamase_E169A|1.007765647 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNAAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->710|beta-lactamase_I171Y|1.007748642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAYPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->711|beta-lactamase_M180Y|1.00769137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTYPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->712|beta-lactamase_S122Q|1.00769137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCQAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->713|beta-lactamase_N152G|1.00769137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHGMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->714|beta-lactamase_A40G|1.007622957 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGGRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->715|beta-lactamase_T138S|1.007583473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLSTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->716|beta-lactamase_Q203T|1.007539591 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRTQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->717|beta-lactamase_M180H|1.007435995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTHPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->718|beta-lactamase_I171S|1.007412148 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEASPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->719|beta-lactamase_T186H|1.0073956309999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAHTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->720|beta-lactamase_M153L|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNLGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->721|beta-lactamase_P60K|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRKEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->722|beta-lactamase_Q204T|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQTLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->723|beta-lactamase_A148K|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTKFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->724|beta-lactamase_S122Y|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCYAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->725|beta-lactamase_K190S|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRSLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->726|beta-lactamase_K109Q|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEQHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->727|beta-lactamase_E195G|1.007303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGGLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->728|beta-lactamase_Q97H|1.00723965 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSHNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->729|beta-lactamase_M180V|1.007173681 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTVPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->730|beta-lactamase_T186Q|1.007167817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAQTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->731|beta-lactamase_S80H|1.00712843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLHRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->732|beta-lactamase_L196W|1.00712843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEWLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->733|beta-lactamase_H94F|1.00712843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIFYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->734|beta-lactamase_S281I|1.007017797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAILIKHW ->735|beta-lactamase_A15I|1.007017797 -MSIQHFRVALIPFFIAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->736|beta-lactamase_A225V|1.006950948 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPVGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->737|beta-lactamase_A225G|1.006917328 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPGGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->738|beta-lactamase_Q204N|1.006885858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQNLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->739|beta-lactamase_S254M|1.006885858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPMRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->740|beta-lactamase_G39N|1.006885858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLNARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->741|beta-lactamase_E145H|1.006885858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKHLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->742|beta-lactamase_V8I|1.006885858 -MSIQHFRIALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->743|beta-lactamase_A84G|1.006782946 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDGGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->744|beta-lactamase_T186D|1.006760565 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMADTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->745|beta-lactamase_I93V|1.00675343 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRVHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->746|beta-lactamase_S254H|1.006725968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPHRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->747|beta-lactamase_S233T|1.006700264 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKTGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->748|beta-lactamase_S221S|1.00661055 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->749|beta-lactamase_E175L|1.00655904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDLRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->750|beta-lactamase_I45F|1.0065278640000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYFELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->751|beta-lactamase_A276H|1.0065278640000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIHEIGASLIKHW ->752|beta-lactamase_F13A|1.0065278640000002 -MSIQHFRVALIPAFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->753|beta-lactamase_V8L|1.0065278640000002 -MSIQHFRLALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->754|beta-lactamase_L196V|1.006462383 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEVLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->755|beta-lactamase_M67C|1.006410096 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMCSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->756|beta-lactamase_E169G|1.006375889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNGAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->757|beta-lactamase_H151Y|1.006367387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLYNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->758|beta-lactamase_H94K|1.006367387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIKYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->759|beta-lactamase_P172A|1.006328978 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIANDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->760|beta-lactamase_M180A|1.006302004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTAPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->761|beta-lactamase_K109E|1.006244146 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEEHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->762|beta-lactamase_T193I|1.00621766 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLIGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->763|beta-lactamase_L55I|1.006176613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIIESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->764|beta-lactamase_R118T|1.006123251 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVTELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->765|beta-lactamase_L282M|1.005946159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASMIKHW ->766|beta-lactamase_A77C|1.005946159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGCVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->767|beta-lactamase_A77Q|1.005946159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGQVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->768|beta-lactamase_G39R|1.005946159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLRARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->769|beta-lactamase_R273G|1.005946159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNGQIAEIGASLIKHW ->770|beta-lactamase_Q97S|1.005946159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSSNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->771|beta-lactamase_A16H|1.005946159 -MSIQHFRVALIPFFAHFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->772|beta-lactamase_H5K|1.005946159 -MSIQKFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->773|beta-lactamase_I11C|1.005946159 -MSIQHFRVALCPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->774|beta-lactamase_Q97T|1.00566205 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSTNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->775|beta-lactamase_D250A|1.005655307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPAGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->776|beta-lactamase_L167I|1.005597156 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEINEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->777|beta-lactamase_T112N|1.005597156 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLNDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->778|beta-lactamase_A225S|1.005568325 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPSGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->779|beta-lactamase_N173K|1.005534412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPKDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->780|beta-lactamase_A84Q|1.005493657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDQGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->781|beta-lactamase_T112V|1.005493657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLVDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->782|beta-lactamase_F14I|1.005457496 -MSIQHFRVALIPFIAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->783|beta-lactamase_L223C|1.005427883 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSACPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->784|beta-lactamase_A280R|1.005414982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGRSLIKHW ->785|beta-lactamase_E102A|1.005414982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVAYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->786|beta-lactamase_A266S|1.005372273 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQSTMDERNRQIAEIGASLIKHW ->787|beta-lactamase_Q274A|1.005303176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRAIAEIGASLIKHW ->788|beta-lactamase_E166N|1.005303176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPNLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->789|beta-lactamase_K252M|1.005303176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGMPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->790|beta-lactamase_Q265F|1.005303176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSFATMDERNRQIAEIGASLIKHW ->791|beta-lactamase_H24D|1.005303176 -MSIQHFRVALIPFFAAFCLPVFADPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->792|beta-lactamase_E277T|1.0052275309999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIATIGASLIKHW ->793|beta-lactamase_P25H|1.0052275309999998 -MSIQHFRVALIPFFAAFCLPVFAHHETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->794|beta-lactamase_T267S|1.00516938 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQASMDERNRQIAEIGASLIKHW ->795|beta-lactamase_E237D|1.005164591 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGDRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->796|beta-lactamase_A222I|1.005131753 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSILPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->797|beta-lactamase_A148C|1.005131753 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTCFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->798|beta-lactamase_M153A|1.005052297 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNAGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->799|beta-lactamase_R118C|1.00500646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVCELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->800|beta-lactamase_Q37R|1.00498535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDRLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->801|beta-lactamase_F228Y|1.004835526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWYIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->802|beta-lactamase_L111I|1.004835526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHITDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->803|beta-lactamase_G90T|1.004835526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLTRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->804|beta-lactamase_E166I|1.004835526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPILNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->805|beta-lactamase_T186S|1.004766918 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMASTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->806|beta-lactamase_A200C|1.004756949 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLCSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->807|beta-lactamase_S221K|1.004724502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRKALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->808|beta-lactamase_H94R|1.004693129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIRYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->809|beta-lactamase_K144T|1.004626964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPTELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->810|beta-lactamase_T139I|1.00448017 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTIIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->811|beta-lactamase_L10A|1.00448017 -MSIQHFRVAAIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->812|beta-lactamase_L146M|1.004379896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEMTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->813|beta-lactamase_L223T|1.004379896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSATPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->814|beta-lactamase_N50Y|1.004379896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLYSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->815|beta-lactamase_N152K|1.004332692 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHKMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->816|beta-lactamase_R189A|1.00429526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLAKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->817|beta-lactamase_A222V|1.004238477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->818|beta-lactamase_A266M|1.004200948 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQMTMDERNRQIAEIGASLIKHW ->819|beta-lactamase_K284L|1.004200948 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLILHW ->820|beta-lactamase_S2T|1.004200948 -MTIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->821|beta-lactamase_L191L|1.004180693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->822|beta-lactamase_E61R|1.004131851 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPRERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->823|beta-lactamase_S254N|1.004045846 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPNRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->824|beta-lactamase_T267G|1.004045846 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAGMDERNRQIAEIGASLIKHW ->825|beta-lactamase_R189S|1.004020925 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLSKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->826|beta-lactamase_A211C|1.003975772 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMECDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->827|beta-lactamase_Q203V|1.003975772 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRVQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->828|beta-lactamase_A200R|1.003953391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLRSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->829|beta-lactamase_K213R|1.003950655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADRVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->830|beta-lactamase_A266K|1.003935799 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQKTMDERNRQIAEIGASLIKHW ->831|beta-lactamase_G90A|1.003929838 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLARRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->832|beta-lactamase_D250K|1.003833473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPKGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->833|beta-lactamase_I206F|1.003790276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLFDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->834|beta-lactamase_Q37S|1.003790276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDSLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->835|beta-lactamase_H94W|1.003790276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIWYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->836|beta-lactamase_A222E|1.003743168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSELPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->837|beta-lactamase_A124A|1.003716137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->838|beta-lactamase_E145R|1.003655502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKRLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->839|beta-lactamase_S281Q|1.003634881 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAQLIKHW ->840|beta-lactamase_L111T|1.003634881 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHTTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->841|beta-lactamase_N173S|1.003338165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPSDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->842|beta-lactamase_E270K|1.003290373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDKRNRQIAEIGASLIKHW ->843|beta-lactamase_T138G|1.003290373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLGTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->844|beta-lactamase_E195D|1.003290373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGDLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->845|beta-lactamase_A246I|1.003245612 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAILGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->846|beta-lactamase_S122I|1.003203685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCIAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->847|beta-lactamase_Q97I|1.003203685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSINDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->848|beta-lactamase_S240A|1.003190197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGARGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->849|beta-lactamase_D269G|1.003190197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMGERNRQIAEIGASLIKHW ->850|beta-lactamase_H94Q|1.003187559 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIQYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->851|beta-lactamase_L160I|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRIDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->852|beta-lactamase_T186N|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMANTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->853|beta-lactamase_T186Y|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAYTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->854|beta-lactamase_R189H|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLHKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->855|beta-lactamase_E237R|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->856|beta-lactamase_T112G|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLGDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->857|beta-lactamase_K284A|1.003126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIAHW ->858|beta-lactamase_P60S|1.00309872 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRSEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->859|beta-lactamase_I45C|1.002997371 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYCELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->860|beta-lactamase_H156C|1.002997371 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDCVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->861|beta-lactamase_Q97A|1.002969029 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSANDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->862|beta-lactamase_A148Y|1.00280474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTYFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->863|beta-lactamase_K190G|1.00280474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRGLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->864|beta-lactamase_P12C|1.00280474 -MSIQHFRVALICFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->865|beta-lactamase_D250R|1.002772684 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPRGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->866|beta-lactamase_S96T|1.002766527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYTQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->867|beta-lactamase_L188F|1.002731245 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTFRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->868|beta-lactamase_Q86L|1.002731245 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGLEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->869|beta-lactamase_K252R|1.002684724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGRPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->870|beta-lactamase_Q88S|1.002655796 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQESLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->871|beta-lactamase_V42L|1.002649638 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARLGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->872|beta-lactamase_A170G|1.002640452 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEGIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->873|beta-lactamase_F228F|1.002595167 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->874|beta-lactamase_Q86T|1.002567152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGTEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->875|beta-lactamase_P12F|1.002567152 -MSIQHFRVALIFFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->876|beta-lactamase_L196M|1.002488673 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEMLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->877|beta-lactamase_A225I|1.002488673 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPIGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->878|beta-lactamase_A211S|1.002426124 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMESDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->879|beta-lactamase_H156Q|1.002426124 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDQVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->880|beta-lactamase_Q88E|1.002375205 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEELGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->881|beta-lactamase_Q88N|1.002323309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQENLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->882|beta-lactamase_L135L|1.002287225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->883|beta-lactamase_P12H|1.002228118 -MSIQHFRVALIHFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->884|beta-lactamase_T198S|1.002147684 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLSLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->885|beta-lactamase_E175Y|1.002128528 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDYRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->886|beta-lactamase_V31C|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKCKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->887|beta-lactamase_A77N|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGNVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->888|beta-lactamase_E46T|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYITLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->889|beta-lactamase_Q274E|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNREIAEIGASLIKHW ->890|beta-lactamase_S281H|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAHLIKHW ->891|beta-lactamase_L49V|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDVNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->892|beta-lactamase_I206W|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLWDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->893|beta-lactamase_T139Q|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTQIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->894|beta-lactamase_G216Q|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAQPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->895|beta-lactamase_A280N|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGNSLIKHW ->896|beta-lactamase_S254E|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPERIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->897|beta-lactamase_S122K|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCKAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->898|beta-lactamase_L111M|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHMTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->899|beta-lactamase_D33G|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKGAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->900|beta-lactamase_D207Q|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIQWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->901|beta-lactamase_E119D|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRDLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->902|beta-lactamase_L196F|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEFLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->903|beta-lactamase_Q203N|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRNQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->904|beta-lactamase_D36S|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAESQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->905|beta-lactamase_E26A|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPATLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->906|beta-lactamase_Q86D|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGDEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->907|beta-lactamase_T112A|1.001873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLADGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->908|beta-lactamase_S2Q|1.001873935 -MQIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->909|beta-lactamase_S221T|1.001833669 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRTALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->910|beta-lactamase_A182G|1.00169097 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPGAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->911|beta-lactamase_S57S|1.001655125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->912|beta-lactamase_E237L|1.001629007 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGLRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->913|beta-lactamase_K53S|1.001503714 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGSILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->914|beta-lactamase_D269S|1.001495113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMSERNRQIAEIGASLIKHW ->915|beta-lactamase_S96G|1.001339914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYGQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->916|beta-lactamase_A225C|1.001326427 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPCGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->917|beta-lactamase_N173F|1.0013122559999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPFDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->918|beta-lactamase_A170S|1.001281665 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNESIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->919|beta-lactamase_M153I|1.001209148 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNIGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->920|beta-lactamase_L167V|1.001180805 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEVNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->921|beta-lactamase_E61T|1.00115002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPTERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->922|beta-lactamase_E175W|1.001016615 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDWRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->923|beta-lactamase_A148I|1.000823104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTIFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->924|beta-lactamase_A280H|1.000823104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGHSLIKHW ->925|beta-lactamase_E195Q|1.000823104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGQLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->926|beta-lactamase_I206T|1.000769644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLTDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->927|beta-lactamase_E270M|1.000710516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDMRNRQIAEIGASLIKHW ->928|beta-lactamase_D269Y|1.000710516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMYERNRQIAEIGASLIKHW ->929|beta-lactamase_A34S|1.000644644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDSEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->930|beta-lactamase_R118Q|1.000644644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVQELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->931|beta-lactamase_T138M|1.000570856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLMTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->932|beta-lactamase_H94N|1.000570856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRINYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->933|beta-lactamase_V8Q|1.000570856 -MSIQHFRQALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->934|beta-lactamase_E166Q|1.0005388000000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPQLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->935|beta-lactamase_Q88D|1.00053059 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEDLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->936|beta-lactamase_H151Q|1.000516517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLQNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->937|beta-lactamase_A182S|1.000441947 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPSAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->938|beta-lactamase_A170C|1.000393178 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNECIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->939|beta-lactamase_E169T|1.000393178 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNTAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->940|beta-lactamase_M115L|1.000322615 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGLTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->941|beta-lactamase_K144I|1.000322615 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPIELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->942|beta-lactamase_D250G|1.000295348 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPGGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->943|beta-lactamase_M127W|1.000284793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITWSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->944|beta-lactamase_K252A|1.000284793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGAPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->945|beta-lactamase_L219L|1.00023522 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->946|beta-lactamase_V42I|1.000224492 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARIGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->947|beta-lactamase_P249K|1.000159304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGKDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->948|beta-lactamase_E169L|1.000159304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNLAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->949|beta-lactamase_K213L|1.00011982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADLVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->950|beta-lactamase_N50S|0.999979867 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLSSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->951|beta-lactamase_M67G|0.999837862 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMGSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->952|beta-lactamase_T261V|0.999837862 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYVTGSQATMDERNRQIAEIGASLIKHW ->953|beta-lactamase_G85G|0.999638972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->954|beta-lactamase_I244V|0.999612295 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->955|beta-lactamase_Q86H|0.99957975 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGHEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->956|beta-lactamase_D207T|0.999547009 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLITWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->957|beta-lactamase_D36Y|0.999478597 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEYQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->958|beta-lactamase_H24R|0.999478597 -MSIQHFRVALIPFFAAFCLPVFARPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->959|beta-lactamase_I259V|0.999415266 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVVYTTGSQATMDERNRQIAEIGASLIKHW ->960|beta-lactamase_V72P|0.999367963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKPLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->961|beta-lactamase_A148H|0.999367963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTHFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->962|beta-lactamase_K190H|0.999367963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRHLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->963|beta-lactamase_A225Y|0.999367963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPYGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->964|beta-lactamase_E175N|0.999367963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDNRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->965|beta-lactamase_K109L|0.999367963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTELHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->966|beta-lactamase_Q4S|0.999367963 -MSISHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->967|beta-lactamase_P12A|0.999314308 -MSIQHFRVALIAFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->968|beta-lactamase_A266G|0.999227033 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQGTMDERNRQIAEIGASLIKHW ->969|beta-lactamase_A148V|0.999221071 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTVFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->970|beta-lactamase_D36N|0.999214523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAENQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->971|beta-lactamase_H151N|0.999214523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLNNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->972|beta-lactamase_I171F|0.999159206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAFPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->973|beta-lactamase_A266R|0.999113174 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQRTMDERNRQIAEIGASLIKHW ->974|beta-lactamase_Q265I|0.999041145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSIATMDERNRQIAEIGASLIKHW ->975|beta-lactamase_W163M|0.998965207 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRMEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->976|beta-lactamase_I171D|0.998912334 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEADPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->977|beta-lactamase_Q203G|0.998912334 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRGQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->978|beta-lactamase_H151G|0.998912334 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLGNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->979|beta-lactamase_Q265R|0.998854574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSRATMDERNRQIAEIGASLIKHW ->980|beta-lactamase_F22L|0.998784695 -MSIQHFRVALIPFFAAFCLPVLAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->981|beta-lactamase_R238Y|0.998776388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEYGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->982|beta-lactamase_S57M|0.998771306 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEMFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->983|beta-lactamase_S96E|0.998771306 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYEQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->984|beta-lactamase_A211G|0.998733972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEGDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->985|beta-lactamase_P172D|0.998721267 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIDNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->986|beta-lactamase_L223V|0.998711102 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAVPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->987|beta-lactamase_C75V|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLVGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->988|beta-lactamase_A182W|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPWAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->989|beta-lactamase_G90M|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLMRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->990|beta-lactamase_G90N|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLNRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->991|beta-lactamase_R159K|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTKLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->992|beta-lactamase_T267E|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAEMDERNRQIAEIGASLIKHW ->993|beta-lactamase_H94L|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRILYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->994|beta-lactamase_Q97D|0.998616204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSDNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->995|beta-lactamase_Q97G|0.998539289 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSGNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->996|beta-lactamase_K252S|0.998439601 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGSPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->997|beta-lactamase_A276R|0.998428264 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIREIGASLIKHW ->998|beta-lactamase_T198K|0.998408229 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLKLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->999|beta-lactamase_A246V|0.998393667 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAVLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1000|beta-lactamase_S221R|0.99827844 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRRALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1001|beta-lactamase_Q37H|0.998254203 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDHLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1002|beta-lactamase_F13L|0.998188135 -MSIQHFRVALIPLFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1003|beta-lactamase_A182C|0.998172009 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPCAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1004|beta-lactamase_E61N|0.998115031 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPNERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1005|beta-lactamase_P172E|0.998092651 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIENDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1006|beta-lactamase_K53H|0.998041341 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGHILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1007|beta-lactamase_Q4R|0.997956998 -MSIRHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1008|beta-lactamase_K53R|0.997948984 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGRILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1009|beta-lactamase_L150I|0.997925137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFIHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1010|beta-lactamase_S57E|0.997901095 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEEFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1011|beta-lactamase_M127E|0.997801798 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITESDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1012|beta-lactamase_K53M|0.997801798 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGMILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1013|beta-lactamase_R202S|0.997750195 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASSQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1014|beta-lactamase_A200P|0.997715109 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLPSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1015|beta-lactamase_K53L|0.997670446 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGLILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1016|beta-lactamase_R118F|0.997587471 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVFELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1017|beta-lactamase_H156R|0.997587471 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDRVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1018|beta-lactamase_H151L|0.997507916 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLLNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1019|beta-lactamase_Q88F|0.997456704 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEFLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1020|beta-lactamase_Q88Y|0.997411259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEYLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1021|beta-lactamase_E169K|0.997380473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNKAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1022|beta-lactamase_A34V|0.99736855 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDVEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1023|beta-lactamase_S281R|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGARLIKHW ->1024|beta-lactamase_I206C|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLCDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1025|beta-lactamase_M180N|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTNPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1026|beta-lactamase_Q203S|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRSQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1027|beta-lactamase_D269H|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMHERNRQIAEIGASLIKHW ->1028|beta-lactamase_R273A|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNAQIAEIGASLIKHW ->1029|beta-lactamase_K284Q|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIQHW ->1030|beta-lactamase_K144F|0.997219996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPFELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1031|beta-lactamase_P20N|0.997219996 -MSIQHFRVALIPFFAAFCLNVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1032|beta-lactamase_D269V|0.997160575 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMVERNRQIAEIGASLIKHW ->1033|beta-lactamase_S96L|0.99713536 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYLQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1034|beta-lactamase_P25Q|0.997031372 -MSIQHFRVALIPFFAAFCLPVFAHQETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1035|beta-lactamase_V117I|0.996987295 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTIRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1036|beta-lactamase_S254G|0.996931196 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPGRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1037|beta-lactamase_F6K|0.996916536 -MSIQHKRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1038|beta-lactamase_S254D|0.996900313 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPDRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1039|beta-lactamase_P12Y|0.996862002 -MSIQHFRVALIYFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1040|beta-lactamase_S122F|0.996661552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCFAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1041|beta-lactamase_E237K|0.996585418 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1042|beta-lactamase_K144L|0.996570661 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPLELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1043|beta-lactamase_D33D|0.996526055 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1044|beta-lactamase_G194D|0.996513096 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTDELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1045|beta-lactamase_P60M|0.99644439 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRMEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1046|beta-lactamase_D33L|0.99644439 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKLAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1047|beta-lactamase_P217Q|0.99644439 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGQLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1048|beta-lactamase_S221Q|0.99644439 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRQALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1049|beta-lactamase_L282V|0.996409304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASVIKHW ->1050|beta-lactamase_D99Q|0.996360829 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNQLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1051|beta-lactamase_E56G|0.996343335 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILGSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1052|beta-lactamase_E61K|0.996189308 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPKERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1053|beta-lactamase_K109T|0.996172889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTETHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1054|beta-lactamase_R238K|0.996150899 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEKGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1055|beta-lactamase_A84L|0.996125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDLGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1056|beta-lactamase_M67N|0.996072518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMNSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1057|beta-lactamase_P253A|0.996056587 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKASRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1058|beta-lactamase_S221A|0.996050919 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRAALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1059|beta-lactamase_A84V|0.995983581 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDVGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1060|beta-lactamase_G39S|0.995950743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLSARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1061|beta-lactamase_S51E|0.995950743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNEGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1062|beta-lactamase_R189W|0.995950743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLWKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1063|beta-lactamase_T267Q|0.995950743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAQMDERNRQIAEIGASLIKHW ->1064|beta-lactamase_Q37W|0.995950743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDWLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1065|beta-lactamase_Y95Y|0.995827742 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1066|beta-lactamase_K53V|0.995784695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGVILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1067|beta-lactamase_R7H|0.995668686 -MSIQHFHVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1068|beta-lactamase_A211L|0.99560907 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMELDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1069|beta-lactamase_R176Q|0.995568608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEQDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1070|beta-lactamase_T186K|0.995517396 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAKTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1071|beta-lactamase_K53Y|0.995517396 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGYILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1072|beta-lactamase_N50K|0.995474785 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLKSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1073|beta-lactamase_P60H|0.995403049 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRHEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1074|beta-lactamase_E195E|0.99536007 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1075|beta-lactamase_I45M|0.995358483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYMELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1076|beta-lactamase_K190A|0.995358483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRALLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1077|beta-lactamase_E145M|0.995358483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKMLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1078|beta-lactamase_I3L|0.995289093 -MSLQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1079|beta-lactamase_M127T|0.995256646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITTSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1080|beta-lactamase_L196P|0.995256646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEPLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1081|beta-lactamase_D269I|0.995256646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMIERNRQIAEIGASLIKHW ->1082|beta-lactamase_L49I|0.99516683 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDINSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1083|beta-lactamase_E169Q|0.995112588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNQAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1084|beta-lactamase_E169D|0.995100371 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNDAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1085|beta-lactamase_P20R|0.995015539 -MSIQHFRVALIPFFAAFCLRVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1086|beta-lactamase_Q4Y|0.995015539 -MSIYHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1087|beta-lactamase_T126S|0.994951231 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAISMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1088|beta-lactamase_A200K|0.994791927 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLKSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1089|beta-lactamase_W163V|0.994791927 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRVEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1090|beta-lactamase_T198N|0.994747654 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLNLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1091|beta-lactamase_Q86Y|0.99463448 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGYEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1092|beta-lactamase_T267A|0.994493061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAAMDERNRQIAEIGASLIKHW ->1093|beta-lactamase_G90S|0.994469996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLSRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1094|beta-lactamase_K144Y|0.994427678 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPYELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1095|beta-lactamase_A183V|0.994125782 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAVMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1096|beta-lactamase_P60Q|0.99407369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRQEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1097|beta-lactamase_Q88T|0.99407369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQETLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1098|beta-lactamase_I3Y|0.994055317 -MSYQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1099|beta-lactamase_S80F|0.99402111 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLFRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1100|beta-lactamase_K144Q|0.993957877 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPQELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1101|beta-lactamase_A225R|0.993819781 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPRGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1102|beta-lactamase_T187D|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATDLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1103|beta-lactamase_S264T|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGTQATMDERNRQIAEIGASLIKHW ->1104|beta-lactamase_A182T|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPTAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1105|beta-lactamase_A183Q|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAQMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1106|beta-lactamase_L49Y|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDYNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1107|beta-lactamase_G194Q|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTQELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1108|beta-lactamase_V106M|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPMTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1109|beta-lactamase_V157A|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHATRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1110|beta-lactamase_L28H|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETHVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1111|beta-lactamase_R81N|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSNVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1112|beta-lactamase_H285Y|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKYW ->1113|beta-lactamase_E169F|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNFAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1114|beta-lactamase_E210Q|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMQADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1115|beta-lactamase_E26K|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPKTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1116|beta-lactamase_E277R|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIARIGASLIKHW ->1117|beta-lactamase_D113N|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTNGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1118|beta-lactamase_Q37T|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDTLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1119|beta-lactamase_L199H|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTHASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1120|beta-lactamase_H156T|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDTVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1121|beta-lactamase_R273T|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNTQIAEIGASLIKHW ->1122|beta-lactamase_R273Y|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNYQIAEIGASLIKHW ->1123|beta-lactamase_E61W|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPWERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1124|beta-lactamase_E195S|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGSLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1125|beta-lactamase_C18W|0.993729574 -MSIQHFRVALIPFFAAFWLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1126|beta-lactamase_I3H|0.993729574 -MSHQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1127|beta-lactamase_P25E|0.993729574 -MSIQHFRVALIPFFAAFCLPVFAHEETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1128|beta-lactamase_P12S|0.993626466 -MSIQHFRVALISFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1129|beta-lactamase_I206S|0.993466869 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLSDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1130|beta-lactamase_A230A|0.993425476 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1131|beta-lactamase_S57Q|0.99339484 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEQFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1132|beta-lactamase_K252C|0.993375489 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGCPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1133|beta-lactamase_D113A|0.993268569 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTAGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1134|beta-lactamase_N173T|0.993268569 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPTDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1135|beta-lactamase_K190Y|0.993186572 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRYLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1136|beta-lactamase_L73V|0.993086591 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVVLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1137|beta-lactamase_L282I|0.993069195 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASIIKHW ->1138|beta-lactamase_A225L|0.993044566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPLGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1139|beta-lactamase_S96A|0.993039386 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYAQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1140|beta-lactamase_E61L|0.993013976 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPLERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1141|beta-lactamase_S96R|0.993001759 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYRQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1142|beta-lactamase_I45L|0.992989152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYLELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1143|beta-lactamase_E145C|0.992989152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKCLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1144|beta-lactamase_D269N|0.992989152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMNERNRQIAEIGASLIKHW ->1145|beta-lactamase_Q265V|0.992941358 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSVATMDERNRQIAEIGASLIKHW ->1146|beta-lactamase_T261I|0.992887018 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYITGSQATMDERNRQIAEIGASLIKHW ->1147|beta-lactamase_Q204A|0.992887018 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQALIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1148|beta-lactamase_V157E|0.992887018 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHETRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1149|beta-lactamase_P217D|0.992887018 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGDLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1150|beta-lactamase_A84H|0.992887018 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDHGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1151|beta-lactamase_E166K|0.99281108 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPKLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1152|beta-lactamase_G226N|0.992752245 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPANWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1153|beta-lactamase_P12W|0.992752245 -MSIQHFRVALIWFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1154|beta-lactamase_A84E|0.992667218 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDEGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1155|beta-lactamase_E237C|0.992667218 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGCRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1156|beta-lactamase_T131S|0.992566064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNSAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1157|beta-lactamase_F13T|0.992487194 -MSIQHFRVALIPTFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1158|beta-lactamase_L196G|0.992443605 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEGLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1159|beta-lactamase_R92L|0.992387116 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRLIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1160|beta-lactamase_P12T|0.992313132 -MSIQHFRVALITFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1161|beta-lactamase_K30A|0.992292315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVAVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1162|beta-lactamase_H151V|0.992292315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLVNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1163|beta-lactamase_S2Y|0.992292315 -MYIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1164|beta-lactamase_L192F|0.992170052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLFTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1165|beta-lactamase_D250F|0.99214298 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPFGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1166|beta-lactamase_S80Q|0.992131154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLQRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1167|beta-lactamase_I11W|0.992100662 -MSIQHFRVALWPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1168|beta-lactamase_E145S|0.992069094 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKSLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1169|beta-lactamase_L188I|0.992056095 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTIRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1170|beta-lactamase_D33E|0.992024919 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKEAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1171|beta-lactamase_E26G|0.992024919 -MSIQHFRVALIPFFAAFCLPVFAHPGTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1172|beta-lactamase_D269L|0.992017686 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMLERNRQIAEIGASLIKHW ->1173|beta-lactamase_E270C|0.991850075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDCRNRQIAEIGASLIKHW ->1174|beta-lactamase_E175K|0.991850075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDKRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1175|beta-lactamase_N98G|0.991850075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQGDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1176|beta-lactamase_S2M|0.991850075 -MMIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1177|beta-lactamase_S240G|0.991774919 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGGRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1178|beta-lactamase_L188V|0.991752734 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTVRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1179|beta-lactamase_R271L|0.991748531 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDELNRQIAEIGASLIKHW ->1180|beta-lactamase_A211K|0.991508402 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEKDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1181|beta-lactamase_G90Y|0.991508402 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLYRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1182|beta-lactamase_A266V|0.99148436 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQVTMDERNRQIAEIGASLIKHW ->1183|beta-lactamase_R118L|0.991402558 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVLELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1184|beta-lactamase_V29C|0.991365028 -MSIQHFRVALIPFFAAFCLPVFAHPETLCKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1185|beta-lactamase_N50H|0.991365028 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLHSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1186|beta-lactamase_E35E|0.991355489 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1187|beta-lactamase_Q86E|0.991315185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGEEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1188|beta-lactamase_P172T|0.991280294 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAITNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1189|beta-lactamase_E175S|0.991276483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDSRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1190|beta-lactamase_E56A|0.991242374 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILASFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1191|beta-lactamase_R189F|0.991236412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLFKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1192|beta-lactamase_N50A|0.991236412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLASGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1193|beta-lactamase_P60T|0.991223609 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRTEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1194|beta-lactamase_D250M|0.991217745 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPMGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1195|beta-lactamase_I93L|0.991188523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRLHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1196|beta-lactamase_E175R|0.99111669 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDRRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1197|beta-lactamase_Q274K|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRKIAEIGASLIKHW ->1198|beta-lactamase_E56D|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILDSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1199|beta-lactamase_V101D|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLDEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1200|beta-lactamase_S57K|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEKFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1201|beta-lactamase_T138Y|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLYTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1202|beta-lactamase_R92K|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRKIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1203|beta-lactamase_N50F|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLFSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1204|beta-lactamase_N50R|0.991014755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLRSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1205|beta-lactamase_L150V|0.990941947 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFVHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1206|beta-lactamase_Q86K|0.990892787 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGKEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1207|beta-lactamase_W163Y|0.990830727 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRYEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1208|beta-lactamase_P172L|0.990760066 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAILNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1209|beta-lactamase_L47M|0.990749902 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEMDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1210|beta-lactamase_A183T|0.990724394 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPATMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1211|beta-lactamase_D269Q|0.99071726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMQERNRQIAEIGASLIKHW ->1212|beta-lactamase_D250C|0.990567631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPCGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1213|beta-lactamase_H24E|0.990542611 -MSIQHFRVALIPFFAAFCLPVFAEPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1214|beta-lactamase_A200T|0.990471853 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLTSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1215|beta-lactamase_T138D|0.990471853 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLDTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1216|beta-lactamase_G226G|0.990442958 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1217|beta-lactamase_V82V|0.990415269 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1218|beta-lactamase_E270A|0.99034656 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDARNRQIAEIGASLIKHW ->1219|beta-lactamase_E270Q|0.99034656 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDQRNRQIAEIGASLIKHW ->1220|beta-lactamase_S122A|0.990239152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCAAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1221|beta-lactamase_T138C|0.990239152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLCTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1222|beta-lactamase_E175C|0.990239152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDCRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1223|beta-lactamase_E237Y|0.990239152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGYRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1224|beta-lactamase_E102M|0.990239152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVMYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1225|beta-lactamase_Q265D|0.990239152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSDATMDERNRQIAEIGASLIKHW ->1226|beta-lactamase_T139V|0.990124707 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTVIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1227|beta-lactamase_S122V|0.990124707 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCVAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1228|beta-lactamase_D207R|0.990027561 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIRWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1229|beta-lactamase_I275F|0.989970582 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQFAEIGASLIKHW ->1230|beta-lactamase_K252Y|0.989928851 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGYPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1231|beta-lactamase_S80W|0.989871677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLWRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1232|beta-lactamase_V157I|0.989871677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHITRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1233|beta-lactamase_S122H|0.989871677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCHAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1234|beta-lactamase_V29T|0.989871677 -MSIQHFRVALIPFFAAFCLPVFAHPETLTKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1235|beta-lactamase_Q88W|0.989871677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEWLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1236|beta-lactamase_S122G|0.98982027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCGAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1237|beta-lactamase_I125L|0.989788702 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAALTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1238|beta-lactamase_H5Y|0.989788702 -MSIQYFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1239|beta-lactamase_W163I|0.989752052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRIEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1240|beta-lactamase_S57R|0.989734167 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILERFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1241|beta-lactamase_H110K|0.989657349 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKKLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1242|beta-lactamase_D269T|0.989657349 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMTERNRQIAEIGASLIKHW ->1243|beta-lactamase_A9F|0.989517005 -MSIQHFRVFLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1244|beta-lactamase_T267K|0.989480356 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAKMDERNRQIAEIGASLIKHW ->1245|beta-lactamase_E166V|0.989447518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPVLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1246|beta-lactamase_I45T|0.989417807 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYTELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1247|beta-lactamase_I206K|0.989417807 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLKDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1248|beta-lactamase_E277I|0.989417807 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAIIGASLIKHW ->1249|beta-lactamase_K109N|0.989344116 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTENHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1250|beta-lactamase_K53E|0.989287138 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGEILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1251|beta-lactamase_A246C|0.989174257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIACLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1252|beta-lactamase_E270V|0.989136923 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDVRNRQIAEIGASLIKHW ->1253|beta-lactamase_A148A|0.989126446 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1254|beta-lactamase_P172V|0.989090403 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIVNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1255|beta-lactamase_E46Q|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIQLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1256|beta-lactamase_A276Q|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIQEIGASLIKHW ->1257|beta-lactamase_Q274H|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRHIAEIGASLIKHW ->1258|beta-lactamase_Q274Y|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRYIAEIGASLIKHW ->1259|beta-lactamase_I206Q|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLQDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1260|beta-lactamase_I206R|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLRDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1261|beta-lactamase_K30M|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVMVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1262|beta-lactamase_S51N|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNNGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1263|beta-lactamase_D99M|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNMLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1264|beta-lactamase_D207K|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIKWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1265|beta-lactamase_E270S|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDSRNRQIAEIGASLIKHW ->1266|beta-lactamase_E210C|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMCADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1267|beta-lactamase_I54F|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKFLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1268|beta-lactamase_E108I|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTIKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1269|beta-lactamase_Q37I|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDILGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1270|beta-lactamase_L199A|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTAASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1271|beta-lactamase_K213H|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADHVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1272|beta-lactamase_K284N|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLINHW ->1273|beta-lactamase_E195T|0.988842944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGTLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1274|beta-lactamase_F17Y|0.988842944 -MSIQHFRVALIPFFAAYCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1275|beta-lactamase_M180R|0.988787236 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTRPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1276|beta-lactamase_A84S|0.98866683 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDSGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1277|beta-lactamase_S122R|0.988639367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCRAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1278|beta-lactamase_M180I|0.988493941 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTIPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1279|beta-lactamase_R118D|0.988459636 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVDELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1280|beta-lactamase_Q203A|0.988439894 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRAQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1281|beta-lactamase_S57H|0.988418002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEHFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1282|beta-lactamase_R238Q|0.988309226 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEQGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1283|beta-lactamase_G194E|0.988299941 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTEELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1284|beta-lactamase_V157R|0.988299941 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHRTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1285|beta-lactamase_V8R|0.988244625 -MSIQHFRRALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1286|beta-lactamase_G251A|0.988224883 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDAKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1287|beta-lactamase_L160M|0.988212373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRMDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1288|beta-lactamase_D113Q|0.988091185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTQGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1289|beta-lactamase_S51S|0.988072525 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1290|beta-lactamase_S96Q|0.987912138 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYQQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1291|beta-lactamase_A84R|0.987912138 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDRGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1292|beta-lactamase_H5Q|0.987853206 -MSIQQFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1293|beta-lactamase_L111L|0.987852188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1294|beta-lactamase_E145V|0.987844214 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKVLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1295|beta-lactamase_I283V|0.987770231 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLVKHW ->1296|beta-lactamase_A266E|0.98769312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQETMDERNRQIAEIGASLIKHW ->1297|beta-lactamase_G226T|0.987621286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPATWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1298|beta-lactamase_K190Q|0.987621286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRQLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1299|beta-lactamase_F22S|0.987621286 -MSIQHFRVALIPFFAAFCLPVSAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1300|beta-lactamase_P20E|0.987621286 -MSIQHFRVALIPFFAAFCLEVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1301|beta-lactamase_M268L|0.987479281 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATLDERNRQIAEIGASLIKHW ->1302|beta-lactamase_Q4K|0.987395035 -MSIKHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1303|beta-lactamase_P60R|0.98737412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRREERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1304|beta-lactamase_D250L|0.987332877 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPLGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1305|beta-lactamase_L28M|0.987299844 -MSIQHFRVALIPFFAAFCLPVFAHPETMVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1306|beta-lactamase_A170Y|0.987247263 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEYIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1307|beta-lactamase_A280G|0.987247263 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGGSLIKHW ->1308|beta-lactamase_A230G|0.987228987 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIGDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1309|beta-lactamase_E61V|0.987209636 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPVERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1310|beta-lactamase_Q88K|0.987197909 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEKLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1311|beta-lactamase_R189C|0.987191165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLCKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1312|beta-lactamase_L10M|0.98706597 -MSIQHFRVAMIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1313|beta-lactamase_M127V|0.986958952 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITVSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1314|beta-lactamase_I11V|0.986932369 -MSIQHFRVALVPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1315|beta-lactamase_Q88R|0.98689269 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQERLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1316|beta-lactamase_D207L|0.986838155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLILWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1317|beta-lactamase_A266Q|0.986800723 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQQTMDERNRQIAEIGASLIKHW ->1318|beta-lactamase_P60I|0.986748632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRIEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1319|beta-lactamase_S80N|0.986726446 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLNRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1320|beta-lactamase_K190V|0.986700841 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRVLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1321|beta-lactamase_S281C|0.98667113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGACLIKHW ->1322|beta-lactamase_S96W|0.98667113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYWQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1323|beta-lactamase_G90H|0.98667113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLHRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1324|beta-lactamase_D113K|0.98667113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTKGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1325|beta-lactamase_K53Q|0.986616106 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGQILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1326|beta-lactamase_T187S|0.986590696 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATSLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1327|beta-lactamase_E166G|0.986559715 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPGLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1328|beta-lactamase_S281N|0.986543393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGANLIKHW ->1329|beta-lactamase_M153T|0.986543393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNTGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1330|beta-lactamase_A222M|0.986543393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSMLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1331|beta-lactamase_A16Q|0.986543393 -MSIQHFRVALIPFFAQFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1332|beta-lactamase_Q86R|0.98648016 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGREQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1333|beta-lactamase_P172S|0.986447224 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAISNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1334|beta-lactamase_E166R|0.986421814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPRLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1335|beta-lactamase_A182H|0.986399629 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPHAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1336|beta-lactamase_L10V|0.986399629 -MSIQHFRVAVIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1337|beta-lactamase_T193L|0.986293393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLLGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1338|beta-lactamase_E102T|0.986293393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVTYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1339|beta-lactamase_E56T|0.986236708 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILTSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1340|beta-lactamase_S254V|0.986192533 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPVRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1341|beta-lactamase_K144C|0.986146892 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPCELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1342|beta-lactamase_S221H|0.986110633 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRHALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1343|beta-lactamase_S281L|0.986050625 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGALLIKHW ->1344|beta-lactamase_K213C|0.985982506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADCVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1345|beta-lactamase_D269K|0.985955434 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMKERNRQIAEIGASLIKHW ->1346|beta-lactamase_A266T|0.985805317 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQTTMDERNRQIAEIGASLIKHW ->1347|beta-lactamase_S96D|0.985796716 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYDQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1348|beta-lactamase_T139S|0.9857155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTSIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1349|beta-lactamase_H110H|0.985587601 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1350|beta-lactamase_A77Y|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGYVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1351|beta-lactamase_A276F|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIFEIGASLIKHW ->1352|beta-lactamase_V101I|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLIEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1353|beta-lactamase_T198H|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLHLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1354|beta-lactamase_E270I|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDIRNRQIAEIGASLIKHW ->1355|beta-lactamase_Q203L|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRLQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1356|beta-lactamase_K32H|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVHDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1357|beta-lactamase_H156E|0.985585223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDEVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1358|beta-lactamase_A9H|0.985585223 -MSIQHFRVHLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1359|beta-lactamase_F22Q|0.985585223 -MSIQHFRVALIPFFAAFCLPVQAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1360|beta-lactamase_L150C|0.985528831 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFCHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1361|beta-lactamase_N173Y|0.985443511 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPYDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1362|beta-lactamase_M66L|0.985330629 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPLMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1363|beta-lactamase_E145Q|0.98531812 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKQLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1364|beta-lactamase_K252I|0.98531812 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGIPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1365|beta-lactamase_L199R|0.985288995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTRASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1366|beta-lactamase_R238G|0.985275508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEGGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1367|beta-lactamase_V29L|0.985252737 -MSIQHFRVALIPFFAAFCLPVFAHPETLLKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1368|beta-lactamase_P172Q|0.985226446 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIQNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1369|beta-lactamase_P60V|0.985003421 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRVEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1370|beta-lactamase_I275V|0.984844801 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQVAEIGASLIKHW ->1371|beta-lactamase_I45A|0.984727912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYAELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1372|beta-lactamase_K32S|0.984727912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVSDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1373|beta-lactamase_N98V|0.984727912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQVDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1374|beta-lactamase_Q265Y|0.984727912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSYATMDERNRQIAEIGASLIKHW ->1375|beta-lactamase_A9K|0.984727912 -MSIQHFRVKLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1376|beta-lactamase_F17T|0.984727912 -MSIQHFRVALIPFFAATCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1377|beta-lactamase_K144M|0.984654418 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPMELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1378|beta-lactamase_S80M|0.984627052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLMRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1379|beta-lactamase_R255K|0.984627052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSKIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1380|beta-lactamase_A133G|0.984603987 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAGNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1381|beta-lactamase_N50L|0.984567142 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLLSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1382|beta-lactamase_L167M|0.984461787 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEMNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1383|beta-lactamase_T267N|0.984260262 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQANMDERNRQIAEIGASLIKHW ->1384|beta-lactamase_K144V|0.984151779 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPVELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1385|beta-lactamase_P172M|0.984104378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIMNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1386|beta-lactamase_S221N|0.984069977 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRNALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1387|beta-lactamase_P172I|0.984069977 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIINDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1388|beta-lactamase_D48E|0.98402326 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELELNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1389|beta-lactamase_H94S|0.984008894 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRISYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1390|beta-lactamase_E108G|0.983923084 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTGKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1391|beta-lactamase_Y44F|0.983824277 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGFIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1392|beta-lactamase_E87M|0.983668882 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQMQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1393|beta-lactamase_I125V|0.983637608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1394|beta-lactamase_G39D|0.983630571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLDARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1395|beta-lactamase_A183H|0.98359871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAHMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1396|beta-lactamase_I54T|0.98359871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKTLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1397|beta-lactamase_P12N|0.98359871 -MSIQHFRVALINFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1398|beta-lactamase_G85H|0.983549062 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAHQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1399|beta-lactamase_E277D|0.983512119 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIADIGASLIKHW ->1400|beta-lactamase_E175F|0.983441947 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDFRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1401|beta-lactamase_W163C|0.983392494 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRCEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1402|beta-lactamase_E56K|0.983383991 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILKSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1403|beta-lactamase_A276K|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIKEIGASLIKHW ->1404|beta-lactamase_Q204S|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQSLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1405|beta-lactamase_V157S|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHSTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1406|beta-lactamase_D207W|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIWWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1407|beta-lactamase_R159H|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTHLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1408|beta-lactamase_E270F|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDFRNRQIAEIGASLIKHW ->1409|beta-lactamase_H151E|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLENMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1410|beta-lactamase_D269F|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMFERNRQIAEIGASLIKHW ->1411|beta-lactamase_R273L|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNLQIAEIGASLIKHW ->1412|beta-lactamase_K109D|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEDHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1413|beta-lactamase_E195R|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGRLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1414|beta-lactamase_Q265M|0.98325821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSMATMDERNRQIAEIGASLIKHW ->1415|beta-lactamase_A9I|0.98325821 -MSIQHFRVILIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1416|beta-lactamase_N173H|0.983093921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPHDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1417|beta-lactamase_E61A|0.983079261 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPAERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1418|beta-lactamase_T178S|0.982998436 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDSTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1419|beta-lactamase_D250Y|0.982950254 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPYGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1420|beta-lactamase_K30L|0.982933542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVLVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1421|beta-lactamase_L55Y|0.982933542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIYESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1422|beta-lactamase_L223I|0.982922596 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAIPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1423|beta-lactamase_L188M|0.982776779 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTMRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1424|beta-lactamase_T126E|0.982776779 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIEMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1425|beta-lactamase_A200Y|0.982776779 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLYSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1426|beta-lactamase_A246Y|0.98269527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAYLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1427|beta-lactamase_Q88L|0.982631548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQELLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1428|beta-lactamase_P60C|0.982623632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRCEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1429|beta-lactamase_K109V|0.982623632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEVHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1430|beta-lactamase_S80T|0.982607701 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLTRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1431|beta-lactamase_E61S|0.982575352 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPSERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1432|beta-lactamase_T126G|0.982568706 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIGMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1433|beta-lactamase_A246F|0.982531079 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAFLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1434|beta-lactamase_R189G|0.982526583 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLGKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1435|beta-lactamase_P12V|0.982503518 -MSIQHFRVALIVFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1436|beta-lactamase_G90V|0.982359656 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLVRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1437|beta-lactamase_A77M|0.982327404 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGMVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1438|beta-lactamase_G90W|0.982327404 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLWRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1439|beta-lactamase_T198E|0.982327404 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLELASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1440|beta-lactamase_H156W|0.982327404 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDWVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1441|beta-lactamase_N152F|0.982327404 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHFMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1442|beta-lactamase_K252T|0.982241106 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGTPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1443|beta-lactamase_V31I|0.982204457 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKIKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1444|beta-lactamase_P12G|0.982204457 -MSIQHFRVALIGFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1445|beta-lactamase_S57G|0.982186777 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEGFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1446|beta-lactamase_N50I|0.982155991 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLISGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1447|beta-lactamase_N50V|0.982155991 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLVSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1448|beta-lactamase_K30R|0.982113868 -MSIQHFRVALIPFFAAFCLPVFAHPETLVRVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1449|beta-lactamase_A246T|0.982100968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIATLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1450|beta-lactamase_P253C|0.982044185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKCSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1451|beta-lactamase_A9C|0.982044185 -MSIQHFRVCLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1452|beta-lactamase_K252N|0.982022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGNPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1453|beta-lactamase_D269M|0.98196551 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMMERNRQIAEIGASLIKHW ->1454|beta-lactamase_K213S|0.981907066 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADSVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1455|beta-lactamase_E145T|0.981826241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKTLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1456|beta-lactamase_S80G|0.9817418 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLGRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1457|beta-lactamase_H94E|0.981735154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIEYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1458|beta-lactamase_S254R|0.98170691 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPRRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1459|beta-lactamase_S96H|0.981685115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYHQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1460|beta-lactamase_H24Q|0.98165345 -MSIQHFRVALIPFFAAFCLPVFAQPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1461|beta-lactamase_E277A|0.981593931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAAIGASLIKHW ->1462|beta-lactamase_P12L|0.98157976 -MSIQHFRVALILFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1463|beta-lactamase_A280C|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGCSLIKHW ->1464|beta-lactamase_H110F|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKFLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1465|beta-lactamase_D207N|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLINWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1466|beta-lactamase_T138I|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLITIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1467|beta-lactamase_E237H|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGHRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1468|beta-lactamase_Q86M|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGMEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1469|beta-lactamase_H156L|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDLVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1470|beta-lactamase_H156S|0.981513008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDSVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1471|beta-lactamase_F14M|0.981513008 -MSIQHFRVALIPFMAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1472|beta-lactamase_L10I|0.981513008 -MSIQHFRVAIIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1473|beta-lactamase_S2F|0.981513008 -MFIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1474|beta-lactamase_S57Y|0.981428763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEYFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1475|beta-lactamase_S57T|0.981354388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILETFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1476|beta-lactamase_F13V|0.981325068 -MSIQHFRVALIPVFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1477|beta-lactamase_A183S|0.981249326 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPASMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1478|beta-lactamase_T139L|0.981024345 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTLIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1479|beta-lactamase_F149M|0.981024345 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAMLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1480|beta-lactamase_M67D|0.981013692 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMDSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1481|beta-lactamase_K252Q|0.98079438 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGQPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1482|beta-lactamase_S80A|0.980738966 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLARVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1483|beta-lactamase_E277N|0.980698602 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIANIGASLIKHW ->1484|beta-lactamase_T198Q|0.980660682 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLQLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1485|beta-lactamase_L223M|0.980612793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAMPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1486|beta-lactamase_L191F|0.980573309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKFLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1487|beta-lactamase_E108S|0.980573309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTSKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1488|beta-lactamase_G226S|0.980482711 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPASWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1489|beta-lactamase_E102R|0.980465901 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVRYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1490|beta-lactamase_E169V|0.980402375 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNVAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1491|beta-lactamase_E270R|0.980308552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDRRNRQIAEIGASLIKHW ->1492|beta-lactamase_T198G|0.980257144 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLGLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1493|beta-lactamase_R238S|0.980256069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGESGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1494|beta-lactamase_S221V|0.980179349 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRVALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1495|beta-lactamase_L120M|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREMCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1496|beta-lactamase_A170W|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEWIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1497|beta-lactamase_S281M|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAMLIKHW ->1498|beta-lactamase_T116E|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMEVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1499|beta-lactamase_A266N|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQNTMDERNRQIAEIGASLIKHW ->1500|beta-lactamase_M180F|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTFPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1501|beta-lactamase_T147V|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELVAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1502|beta-lactamase_A84K|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDKGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1503|beta-lactamase_D207V|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIVWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1504|beta-lactamase_E108H|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTHKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1505|beta-lactamase_L199K|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTKASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1506|beta-lactamase_N98M|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQMDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1507|beta-lactamase_P25V|0.9801556 -MSIQHFRVALIPFFAAFCLPVFAHVETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1508|beta-lactamase_V8M|0.9801556 -MSIQHFRMALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1509|beta-lactamase_R92T|0.980070084 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRTIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1510|beta-lactamase_P172R|0.980014279 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIRNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1511|beta-lactamase_H94D|0.979973133 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIDYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1512|beta-lactamase_I275M|0.979767797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQMAEIGASLIKHW ->1513|beta-lactamase_S96F|0.979767797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYFQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1514|beta-lactamase_T267H|0.979767797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAHMDERNRQIAEIGASLIKHW ->1515|beta-lactamase_L199T|0.979767797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTTASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1516|beta-lactamase_F14V|0.979733884 -MSIQHFRVALIPFVAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1517|beta-lactamase_I54E|0.97958406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKELESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1518|beta-lactamase_I54M|0.97958406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKMLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1519|beta-lactamase_H151S|0.97958406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLSNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1520|beta-lactamase_K213N|0.97951682 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADNVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1521|beta-lactamase_E166A|0.979476945 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPALNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1522|beta-lactamase_A280T|0.979450459 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGTSLIKHW ->1523|beta-lactamase_V8A|0.979450459 -MSIQHFRAALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1524|beta-lactamase_G251S|0.979427297 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDSKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1525|beta-lactamase_A222G|0.979416644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSGLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1526|beta-lactamase_M153V|0.979406675 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNVGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1527|beta-lactamase_M127Q|0.979406675 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITQSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1528|beta-lactamase_Q265P|0.979406675 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSPATMDERNRQIAEIGASLIKHW ->1529|beta-lactamase_Q86N|0.979357125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGNEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1530|beta-lactamase_Q203I|0.97932028 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRIQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1531|beta-lactamase_L167C|0.979269165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPECNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1532|beta-lactamase_T262S|0.979269165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTSGSQATMDERNRQIAEIGASLIKHW ->1533|beta-lactamase_K32L|0.979269165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVLDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1534|beta-lactamase_T126C|0.979069693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAICMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1535|beta-lactamase_A84C|0.979069693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDCGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1536|beta-lactamase_S221M|0.979069693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRMALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1537|beta-lactamase_A183E|0.97895603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAEMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1538|beta-lactamase_S80E|0.978831323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLERVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1539|beta-lactamase_A84A|0.978772882 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1540|beta-lactamase_S80S|0.978748296 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1541|beta-lactamase_E169H|0.978693814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNHAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1542|beta-lactamase_E145D|0.978693814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKDLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1543|beta-lactamase_N152N|0.978665223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1544|beta-lactamase_A124T|0.978653841 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSATITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1545|beta-lactamase_P172Y|0.97860429 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIYNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1546|beta-lactamase_H151T|0.97860429 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLTNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1547|beta-lactamase_S2K|0.97860429 -MKIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1548|beta-lactamase_V31L|0.978458864 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKLKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1549|beta-lactamase_A148F|0.978458864 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTFFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1550|beta-lactamase_D269R|0.978458864 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMRERNRQIAEIGASLIKHW ->1551|beta-lactamase_E108R|0.978458864 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTRKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1552|beta-lactamase_M180G|0.978398954 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTGPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1553|beta-lactamase_L38M|0.978387813 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQMGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1554|beta-lactamase_I256L|0.978290276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRLVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1555|beta-lactamase_T147R|0.978283337 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELRAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1556|beta-lactamase_T107S|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVSEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1557|beta-lactamase_L28V|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETVVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1558|beta-lactamase_P217N|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGNLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1559|beta-lactamase_V29M|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLMKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1560|beta-lactamase_L199F|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTFASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1561|beta-lactamase_Q97W|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSWNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1562|beta-lactamase_K284I|0.978181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIIHW ->1563|beta-lactamase_F22G|0.978181206 -MSIQHFRVALIPFFAAFCLPVGAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1564|beta-lactamase_Q4C|0.978181206 -MSICHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1565|beta-lactamase_L146F|0.977983786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEFTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1566|beta-lactamase_E169R|0.977935799 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNRAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1567|beta-lactamase_E169N|0.977919869 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNNAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1568|beta-lactamase_E108K|0.977919869 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTKKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1569|beta-lactamase_T187N|0.977794967 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATNLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1570|beta-lactamase_S96K|0.977794967 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYKQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1571|beta-lactamase_Q88V|0.977794967 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEVLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1572|beta-lactamase_I125M|0.977721667 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAMTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1573|beta-lactamase_T198A|0.977698798 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLALASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1574|beta-lactamase_A170F|0.977673485 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEFIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1575|beta-lactamase_A280L|0.977673485 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGLSLIKHW ->1576|beta-lactamase_L79M|0.97757888 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVMSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1577|beta-lactamase_W163E|0.97757888 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDREEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1578|beta-lactamase_A77L|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGLVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1579|beta-lactamase_A182Q|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPQAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1580|beta-lactamase_A280W|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGWSLIKHW ->1581|beta-lactamase_T193F|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLFGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1582|beta-lactamase_A84I|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDIGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1583|beta-lactamase_L199S|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTSASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1584|beta-lactamase_H156V|0.977440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDVVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1585|beta-lactamase_E166T|0.977307281 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPTLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1586|beta-lactamase_E237T|0.977274638 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGTRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1587|beta-lactamase_I11F|0.977274638 -MSIQHFRVALFPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1588|beta-lactamase_L247I|0.97722069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAIGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1589|beta-lactamase_E277L|0.97722069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIALIGASLIKHW ->1590|beta-lactamase_W163L|0.977205444 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRLEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1591|beta-lactamase_T158S|0.977178079 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVSRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1592|beta-lactamase_M66I|0.977115041 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPIMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1593|beta-lactamase_Q204V|0.977070573 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQVLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1594|beta-lactamase_M268F|0.977070573 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATFDERNRQIAEIGASLIKHW ->1595|beta-lactamase_Q203D|0.977012129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRDQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1596|beta-lactamase_S96V|0.976991898 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYVQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1597|beta-lactamase_L160A|0.976961699 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRADRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1598|beta-lactamase_F17I|0.976961699 -MSIQHFRVALIPFFAAICLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1599|beta-lactamase_V101A|0.976814318 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLAEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1600|beta-lactamase_G226H|0.976814318 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAHWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1601|beta-lactamase_Q37C|0.976814318 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDCLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1602|beta-lactamase_S122W|0.976626378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCWAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1603|beta-lactamase_K213V|0.976626378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADVVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1604|beta-lactamase_A9G|0.976589924 -MSIQHFRVGLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1605|beta-lactamase_R189N|0.976535878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLNKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1606|beta-lactamase_R41M|0.976535878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAMVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1607|beta-lactamase_E210K|0.976535878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMKADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1608|beta-lactamase_L73A|0.976482613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVALCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1609|beta-lactamase_R271A|0.976447625 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEANRQIAEIGASLIKHW ->1610|beta-lactamase_G90I|0.976447625 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLIRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1611|beta-lactamase_H110Y|0.976447625 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKYLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1612|beta-lactamase_K213I|0.976404232 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADIVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1613|beta-lactamase_R271T|0.976378528 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDETNRQIAEIGASLIKHW ->1614|beta-lactamase_A84D|0.976322918 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDDGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1615|beta-lactamase_L150M|0.976277375 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFMHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1616|beta-lactamase_A276C|0.976277375 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQICEIGASLIKHW ->1617|beta-lactamase_T139D|0.976277375 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTDIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1618|beta-lactamase_N152C|0.976277375 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHCMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1619|beta-lactamase_N152L|0.976277375 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHLMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1620|beta-lactamase_K109I|0.976114943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEIHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1621|beta-lactamase_Q204H|0.976083376 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQHLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1622|beta-lactamase_M127F|0.976036659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITFSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1623|beta-lactamase_D250T|0.976003528 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPTGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1624|beta-lactamase_E277V|0.975874619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAVIGASLIKHW ->1625|beta-lactamase_S80L|0.975829369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLLRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1626|beta-lactamase_A77V|0.975811972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGVVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1627|beta-lactamase_D113S|0.975811972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTSGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1628|beta-lactamase_E102V|0.975811972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVVYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1629|beta-lactamase_C18S|0.975811972 -MSIQHFRVALIPFFAAFSLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1630|beta-lactamase_S80R|0.975761249 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLRRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1631|beta-lactamase_L247V|0.975705151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAVGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1632|beta-lactamase_E56N|0.975705151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILNSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1633|beta-lactamase_E56Q|0.975705151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILQSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1634|beta-lactamase_I11M|0.975601749 -MSIQHFRVALMPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1635|beta-lactamase_T147S|0.975561386 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELSAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1636|beta-lactamase_N168G|0.975546726 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELGEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1637|beta-lactamase_I243V|0.975508219 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGVIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1638|beta-lactamase_L73M|0.97540472 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVMLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1639|beta-lactamase_D207M|0.97540472 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIMWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1640|beta-lactamase_D113Y|0.97540472 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTYGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1641|beta-lactamase_E102S|0.97540472 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVSYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1642|beta-lactamase_Q88M|0.97540472 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEMLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1643|beta-lactamase_P25T|0.975341781 -MSIQHFRVALIPFFAAFCLPVFAHTETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1644|beta-lactamase_E108D|0.975280014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTDKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1645|beta-lactamase_Y44L|0.975235936 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGLIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1646|beta-lactamase_H285R|0.975235936 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKRW ->1647|beta-lactamase_A200I|0.975219615 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLISRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1648|beta-lactamase_F13Y|0.975160389 -MSIQHFRVALIPYFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1649|beta-lactamase_D269C|0.975131167 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMCERNRQIAEIGASLIKHW ->1650|beta-lactamase_R162N|0.975045455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDNWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1651|beta-lactamase_M180W|0.975045455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTWPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1652|beta-lactamase_H285C|0.975045455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKCW ->1653|beta-lactamase_G39Q|0.975045455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLQARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1654|beta-lactamase_D113H|0.975045455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTHGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1655|beta-lactamase_Q86G|0.974978606 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGGEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1656|beta-lactamase_A124S|0.974881167 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSASITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1657|beta-lactamase_K144P|0.974828489 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPPELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1658|beta-lactamase_Y95I|0.974579271 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHISQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1659|beta-lactamase_L160S|0.974543794 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRSDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1660|beta-lactamase_A200V|0.97453881 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLVSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1661|beta-lactamase_E87L|0.974462871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQLQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1662|beta-lactamase_I283M|0.974440295 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLMKHW ->1663|beta-lactamase_E62T|0.974440295 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPETRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1664|beta-lactamase_I54H|0.974440295 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKHLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1665|beta-lactamase_G216A|0.974308356 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAAPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1666|beta-lactamase_T267M|0.974308356 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAMMDERNRQIAEIGASLIKHW ->1667|beta-lactamase_R271I|0.974183063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEINRQIAEIGASLIKHW ->1668|beta-lactamase_L196D|0.974183063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEDLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1669|beta-lactamase_W163N|0.974183063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRNEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1670|beta-lactamase_K32I|0.974183063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVIDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1671|beta-lactamase_F13W|0.974183063 -MSIQHFRVALIPWFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1672|beta-lactamase_I3Q|0.974183063 -MSQQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1673|beta-lactamase_V82C|0.974148368 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRCDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1674|beta-lactamase_E166C|0.974122762 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPCLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1675|beta-lactamase_M127L|0.974114259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITLSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1676|beta-lactamase_Q274R|0.974063829 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRRIAEIGASLIKHW ->1677|beta-lactamase_D113G|0.973995123 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTGGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1678|beta-lactamase_G76S|0.973950362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCSAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1679|beta-lactamase_G39C|0.973950362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLCARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1680|beta-lactamase_E169Y|0.973950362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNYAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1681|beta-lactamase_G251D|0.973895631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDDKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1682|beta-lactamase_E87I|0.973842172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQIQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1683|beta-lactamase_G194P|0.973738868 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTPELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1684|beta-lactamase_S80V|0.973738868 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLVRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1685|beta-lactamase_T267R|0.973738868 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQARMDERNRQIAEIGASLIKHW ->1686|beta-lactamase_N98D|0.973738868 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQDDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1687|beta-lactamase_F13I|0.973738868 -MSIQHFRVALIPIFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1688|beta-lactamase_R7P|0.973738868 -MSIQHFPVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1689|beta-lactamase_I243L|0.973640061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGLIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1690|beta-lactamase_V117L|0.973640061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTLRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1691|beta-lactamase_G90Q|0.973545651 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLQRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1692|beta-lactamase_A133T|0.973368657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTATNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1693|beta-lactamase_E195K|0.973368657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGKLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1694|beta-lactamase_L137M|0.973297215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLMTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1695|beta-lactamase_A235G|0.973285487 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGGGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1696|beta-lactamase_H94A|0.973231929 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIAYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1697|beta-lactamase_S57W|0.973205737 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEWFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1698|beta-lactamase_M127Y|0.973205737 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITYSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1699|beta-lactamase_G194C|0.973129115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTCELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1700|beta-lactamase_F6V|0.973129115 -MSIQHVRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1701|beta-lactamase_G251Q|0.973055424 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDQKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1702|beta-lactamase_E169C|0.973055424 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNCAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1703|beta-lactamase_G194A|0.97298447 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTAELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1704|beta-lactamase_S96Y|0.972970592 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYYQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1705|beta-lactamase_V82I|0.972931108 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRIDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1706|beta-lactamase_L89M|0.972786855 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQMGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1707|beta-lactamase_I11Y|0.972725674 -MSIQHFRVALYPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1708|beta-lactamase_K30V|0.972666546 -MSIQHFRVALIPFFAAFCLPVFAHPETLVVVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1709|beta-lactamase_E56S|0.97262071 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILSSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1710|beta-lactamase_S221C|0.97257243 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRCALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1711|beta-lactamase_G85E|0.972554154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAEQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1712|beta-lactamase_D36D|0.972514635 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1713|beta-lactamase_S221I|0.972513986 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRIALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1714|beta-lactamase_G226D|0.972449091 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPADWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1715|beta-lactamase_K53G|0.972350577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGGILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1716|beta-lactamase_D48D|0.972317819 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1717|beta-lactamase_T147N|0.972288223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELNAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1718|beta-lactamase_E166H|0.972170944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPHLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1719|beta-lactamase_G39L|0.972088751 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLLARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1720|beta-lactamase_F14T|0.971937852 -MSIQHFRVALIPFTAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1721|beta-lactamase_G279A|0.971868364 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIAASLIKHW ->1722|beta-lactamase_G85N|0.971868364 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDANQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1723|beta-lactamase_A200M|0.971868364 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLMSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1724|beta-lactamase_P25S|0.971868364 -MSIQHFRVALIPFFAAFCLPVFAHSETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1725|beta-lactamase_W163K|0.971834939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRKEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1726|beta-lactamase_P217T|0.971680131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGTLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1727|beta-lactamase_V257I|0.971651398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIIVIYTTGSQATMDERNRQIAEIGASLIKHW ->1728|beta-lactamase_V8D|0.971569302 -MSIQHFRDALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1729|beta-lactamase_H156P|0.97129096 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDPVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1730|beta-lactamase_A16T|0.971251085 -MSIQHFRVALIPFFATFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1731|beta-lactamase_G251E|0.971057379 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDEKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1732|beta-lactamase_L160C|0.970952903 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRCDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1733|beta-lactamase_R7G|0.970898563 -MSIQHFGVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1734|beta-lactamase_D113R|0.970800049 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTRGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1735|beta-lactamase_E169E|0.970798035 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1736|beta-lactamase_I283F|0.970755092 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLFKHW ->1737|beta-lactamase_I256V|0.970666546 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1738|beta-lactamase_R118K|0.970653841 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVKELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1739|beta-lactamase_F58L|0.970407066 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESLRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1740|beta-lactamase_L282C|0.970394556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASCIKHW ->1741|beta-lactamase_L55V|0.970303958 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIVESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1742|beta-lactamase_M67T|0.970131753 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMTSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1743|beta-lactamase_Y260L|0.970124717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVILTTGSQATMDERNRQIAEIGASLIKHW ->1744|beta-lactamase_Q88I|0.969911073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEILGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1745|beta-lactamase_L146V|0.96990345 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEVTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1746|beta-lactamase_W163R|0.969638204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1747|beta-lactamase_A245C|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIICALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1748|beta-lactamase_C75A|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLAGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1749|beta-lactamase_T261L|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYLTGSQATMDERNRQIAEIGASLIKHW ->1750|beta-lactamase_A77H|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGHVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1751|beta-lactamase_E46A|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIALDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1752|beta-lactamase_S264G|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGGQATMDERNRQIAEIGASLIKHW ->1753|beta-lactamase_Q274I|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRIIAEIGASLIKHW ->1754|beta-lactamase_Q274S|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRSIAEIGASLIKHW ->1755|beta-lactamase_T116S|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMSVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1756|beta-lactamase_R271Q|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEQNRQIAEIGASLIKHW ->1757|beta-lactamase_G194N|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTNELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1758|beta-lactamase_F228M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWMIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1759|beta-lactamase_T139G|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTGIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1760|beta-lactamase_V106Q|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPQTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1761|beta-lactamase_Q204I|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQILIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1762|beta-lactamase_A211M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEMDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1763|beta-lactamase_V101S|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLSEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1764|beta-lactamase_G251M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDMKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1765|beta-lactamase_L111C|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHCTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1766|beta-lactamase_D33S|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKSAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1767|beta-lactamase_T193W|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLWGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1768|beta-lactamase_S51Q|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNQGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1769|beta-lactamase_E169I|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNIAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1770|beta-lactamase_A84M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDMGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1771|beta-lactamase_G85Q|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAQQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1772|beta-lactamase_R41P|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAPVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1773|beta-lactamase_R41Y|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAYVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1774|beta-lactamase_P172K|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIKNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1775|beta-lactamase_E210A|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMAADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1776|beta-lactamase_E210F|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMFADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1777|beta-lactamase_E210H|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMHADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1778|beta-lactamase_E210M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMMADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1779|beta-lactamase_E210R|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMRADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1780|beta-lactamase_E210Y|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMYADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1781|beta-lactamase_I54A|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKALESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1782|beta-lactamase_R176M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEMDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1783|beta-lactamase_T138F|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLFTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1784|beta-lactamase_T138W|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLWTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1785|beta-lactamase_E145F|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKFLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1786|beta-lactamase_E108N|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTNKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1787|beta-lactamase_E108Q|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTQKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1788|beta-lactamase_D113M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTMGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1789|beta-lactamase_K32V|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVVDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1790|beta-lactamase_R92M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRMIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1791|beta-lactamase_R92Y|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRYIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1792|beta-lactamase_Q86F|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGFEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1793|beta-lactamase_T112C|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLCDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1794|beta-lactamase_R273Q|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNQQIAEIGASLIKHW ->1795|beta-lactamase_R273V|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNVQIAEIGASLIKHW ->1796|beta-lactamase_E102L|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVLYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1797|beta-lactamase_E102N|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVNYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1798|beta-lactamase_K284H|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIHHW ->1799|beta-lactamase_K284M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIMHW ->1800|beta-lactamase_Q265W|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSWATMDERNRQIAEIGASLIKHW ->1801|beta-lactamase_F17A|0.969296433 -MSIQHFRVALIPFFAAACLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1802|beta-lactamase_F22M|0.969296433 -MSIQHFRVALIPFFAAFCLPVMAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1803|beta-lactamase_F22R|0.969296433 -MSIQHFRVALIPFFAAFCLPVRAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1804|beta-lactamase_L19D|0.969296433 -MSIQHFRVALIPFFAAFCDPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1805|beta-lactamase_P25M|0.969296433 -MSIQHFRVALIPFFAAFCLPVFAHMETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1806|beta-lactamase_Q4I|0.969296433 -MSIIHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1807|beta-lactamase_G251R|0.968486523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDRKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1808|beta-lactamase_G85K|0.968210526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAKQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1809|beta-lactamase_L192V|0.968074775 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLVTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1810|beta-lactamase_K284V|0.967975674 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIVHW ->1811|beta-lactamase_M268I|0.967900225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATIDERNRQIAEIGASLIKHW ->1812|beta-lactamase_E270L|0.967815588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDLRNRQIAEIGASLIKHW ->1813|beta-lactamase_T198D|0.967581812 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLDLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1814|beta-lactamase_P165T|0.967511347 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWETELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1815|beta-lactamase_K284G|0.967452414 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIGHW ->1816|beta-lactamase_A222H|0.967380092 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSHLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1817|beta-lactamase_P217S|0.967288223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGSLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1818|beta-lactamase_D250V|0.967143774 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPVGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1819|beta-lactamase_E164E|0.967134682 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1820|beta-lactamase_Q37G|0.967075264 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDGLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1821|beta-lactamase_L218M|0.967023563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPMLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1822|beta-lactamase_I3F|0.967023563 -MSFQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1823|beta-lactamase_E145I|0.966912735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKILTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1824|beta-lactamase_F6L|0.966790471 -MSIQHLRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1825|beta-lactamase_G226K|0.966757926 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAKWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1826|beta-lactamase_I229C|0.966655014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFCADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1827|beta-lactamase_P172C|0.966655014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAICNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1828|beta-lactamase_I259L|0.966530405 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVLYTTGSQATMDERNRQIAEIGASLIKHW ->1829|beta-lactamase_T138L|0.966463556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLLTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1830|beta-lactamase_D207I|0.966421921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIIWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1831|beta-lactamase_E277K|0.966421921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAKIGASLIKHW ->1832|beta-lactamase_E210N|0.966334842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMNADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1833|beta-lactamase_K252F|0.966242289 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGFPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1834|beta-lactamase_P172H|0.966081519 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIHNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1835|beta-lactamase_I3T|0.966081519 -MSTQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1836|beta-lactamase_G39V|0.966065588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLVARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1837|beta-lactamase_M180D|0.966038712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTDPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1838|beta-lactamase_E210T|0.966038712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMTADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1839|beta-lactamase_A225F|0.966038712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPFGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1840|beta-lactamase_N152V|0.965926319 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHVMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1841|beta-lactamase_L10C|0.965806011 -MSIQHFRVACIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1842|beta-lactamase_H285Q|0.965729584 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKQW ->1843|beta-lactamase_S96I|0.96567671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYIQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1844|beta-lactamase_E277G|0.96567671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAGIGASLIKHW ->1845|beta-lactamase_R238W|0.965537441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEWGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1846|beta-lactamase_L150L|0.965525441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1847|beta-lactamase_E277Q|0.965387129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAQIGASLIKHW ->1848|beta-lactamase_M153N|0.965224208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNNGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1849|beta-lactamase_G216M|0.965224208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAMPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1850|beta-lactamase_R7K|0.965224208 -MSIQHFKVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1851|beta-lactamase_S80I|0.965092856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLIRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1852|beta-lactamase_H156F|0.965047215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDFVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1853|beta-lactamase_K53F|0.964952805 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGFILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1854|beta-lactamase_L191I|0.964903939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKILTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1855|beta-lactamase_E62D|0.964853997 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEDRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1856|beta-lactamase_R41N|0.964853997 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGANVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1857|beta-lactamase_S254L|0.964662539 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPLRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1858|beta-lactamase_P217E|0.964529036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGELLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1859|beta-lactamase_Q4A|0.964409803 -MSIAHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1860|beta-lactamase_R162H|0.964327023 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1861|beta-lactamase_T139R|0.964327023 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTRIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1862|beta-lactamase_T126A|0.964266038 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIAMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1863|beta-lactamase_T267C|0.964241312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQACMDERNRQIAEIGASLIKHW ->1864|beta-lactamase_D207C|0.96415257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLICWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1865|beta-lactamase_F22Y|0.96415257 -MSIQHFRVALIPFFAAFCLPVYAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1866|beta-lactamase_A77A|0.964135807 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1867|beta-lactamase_H110R|0.964042035 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKRLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1868|beta-lactamase_G279S|0.963965608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEISASLIKHW ->1869|beta-lactamase_Q86C|0.963965608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGCEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1870|beta-lactamase_R189M|0.9638668 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLMKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1871|beta-lactamase_I11A|0.963729388 -MSIQHFRVALAPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1872|beta-lactamase_R92H|0.96367153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRHIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1873|beta-lactamase_G90F|0.96354741 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLFRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1874|beta-lactamase_S80D|0.963389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLDRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1875|beta-lactamase_E237W|0.963373251 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGWRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1876|beta-lactamase_T131A|0.963312852 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNAAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1877|beta-lactamase_T107A|0.963282164 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVAEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1878|beta-lactamase_S221E|0.96322802 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLREALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1879|beta-lactamase_A77K|0.963188145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGKVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1880|beta-lactamase_E46N|0.963188145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYINLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1881|beta-lactamase_M153H|0.963188145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNHGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1882|beta-lactamase_E119G|0.963188145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRGLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1883|beta-lactamase_Q88G|0.963188145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEGLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1884|beta-lactamase_K252G|0.963188145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGGPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1885|beta-lactamase_E277S|0.962950166 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIASIGASLIKHW ->1886|beta-lactamase_G85S|0.962902668 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDASQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1887|beta-lactamase_T262C|0.962780893 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTCGSQATMDERNRQIAEIGASLIKHW ->1888|beta-lactamase_T112M|0.962780893 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLMDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1889|beta-lactamase_P217H|0.962670455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGHLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1890|beta-lactamase_M67V|0.962660291 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMVSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1891|beta-lactamase_A222P|0.962632828 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSPLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1892|beta-lactamase_L135V|0.962556206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANVLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1893|beta-lactamase_S96M|0.962477922 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYMQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1894|beta-lactamase_Q88C|0.962438047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQECLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1895|beta-lactamase_V157L|0.962315491 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHLTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1896|beta-lactamase_K252L|0.962231441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGLPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1897|beta-lactamase_W163T|0.962214337 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRTEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1898|beta-lactamase_V8E|0.96214524 -MSIQHFREALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1899|beta-lactamase_Q86W|0.962056988 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGWEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1900|beta-lactamase_S254I|0.961778548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPIRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1901|beta-lactamase_W163P|0.961778548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRPEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1902|beta-lactamase_G85D|0.961609568 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDADQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1903|beta-lactamase_I3S|0.961546726 -MSSQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1904|beta-lactamase_G251T|0.961512422 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDTKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1905|beta-lactamase_M67S|0.961477824 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMSSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1906|beta-lactamase_H24L|0.961477824 -MSIQHFRVALIPFFAAFCLPVFALPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1907|beta-lactamase_G85R|0.961358786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDARQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1908|beta-lactamase_S96C|0.961318227 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYCQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1909|beta-lactamase_F6Y|0.961285584 -MSIQHYRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1910|beta-lactamase_C75T|0.961152082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLTGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1911|beta-lactamase_Q204K|0.961152082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQKLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1912|beta-lactamase_E277M|0.961152082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAMIGASLIKHW ->1913|beta-lactamase_R118M|0.961152082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVMELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1914|beta-lactamase_H5N|0.961152082 -MSIQNFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1915|beta-lactamase_P12Q|0.960998348 -MSIQHFRVALIQFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1916|beta-lactamase_W163S|0.960978802 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRSEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1917|beta-lactamase_L55F|0.960953391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIFESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1918|beta-lactamase_A34C|0.960797899 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDCEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1919|beta-lactamase_H285E|0.960797899 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKEW ->1920|beta-lactamase_A276T|0.960764181 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQITEIGASLIKHW ->1921|beta-lactamase_D250W|0.96074483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPWGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1922|beta-lactamase_F70A|0.960672996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTAKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1923|beta-lactamase_R238L|0.960667035 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGELGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1924|beta-lactamase_S254Y|0.960591487 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPYRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1925|beta-lactamase_A77F|0.960411659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGFVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1926|beta-lactamase_A276Y|0.960411659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIYEIGASLIKHW ->1927|beta-lactamase_R271V|0.960411659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEVNRQIAEIGASLIKHW ->1928|beta-lactamase_A280Y|0.960411659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGYSLIKHW ->1929|beta-lactamase_R273D|0.960411659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNDQIAEIGASLIKHW ->1930|beta-lactamase_E61F|0.960411659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPFERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1931|beta-lactamase_T198C|0.960247078 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLCLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1932|beta-lactamase_D36H|0.960205053 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEHQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1933|beta-lactamase_S233G|0.960174756 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKGGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1934|beta-lactamase_I283L|0.960086014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLLKHW ->1935|beta-lactamase_T139N|0.959988575 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTNIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1936|beta-lactamase_P253I|0.959807867 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKISRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1937|beta-lactamase_H94G|0.959761542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIGYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1938|beta-lactamase_E237I|0.959683356 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGIRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1939|beta-lactamase_A211T|0.959643872 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMETDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1940|beta-lactamase_L196L|0.95954666 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1941|beta-lactamase_V258I|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYTTGSQATMDERNRQIAEIGASLIKHW ->1942|beta-lactamase_K30S|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVSVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1943|beta-lactamase_P253H|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKHSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1944|beta-lactamase_V101C|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLCEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1945|beta-lactamase_H151C|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLCNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1946|beta-lactamase_E108T|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTTKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1947|beta-lactamase_K32E|0.959523172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVEDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1948|beta-lactamase_W163A|0.959433552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRAEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1949|beta-lactamase_A182E|0.959292328 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPEAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1950|beta-lactamase_Q204R|0.959292328 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQRLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1951|beta-lactamase_R92F|0.959272586 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRFIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1952|beta-lactamase_R273S|0.95918619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNSQIAEIGASLIKHW ->1953|beta-lactamase_N173V|0.95918619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPVDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1954|beta-lactamase_H5T|0.95918619 -MSIQTFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1955|beta-lactamase_K190L|0.959085526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRLLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1956|beta-lactamase_I275L|0.958948309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQLAEIGASLIKHW ->1957|beta-lactamase_H24I|0.958899345 -MSIQHFRVALIPFFAAFCLPVFAIPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1958|beta-lactamase_F149I|0.958858982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAILHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1959|beta-lactamase_A266H|0.958825068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQHTMDERNRQIAEIGASLIKHW ->1960|beta-lactamase_P172G|0.958805326 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIGNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1961|beta-lactamase_E175G|0.958743168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDGRDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1962|beta-lactamase_A40S|0.958698896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGSRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1963|beta-lactamase_A16A|0.958580354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1964|beta-lactamase_G90R|0.958522781 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLRRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1965|beta-lactamase_F70V|0.958437265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTVKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1966|beta-lactamase_T262N|0.958437265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTNGSQATMDERNRQIAEIGASLIKHW ->1967|beta-lactamase_A16I|0.958437265 -MSIQHFRVALIPFFAIFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1968|beta-lactamase_F14A|0.958437265 -MSIQHFRVALIPFAAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1969|beta-lactamase_H24F|0.958437265 -MSIQHFRVALIPFFAAFCLPVFAFPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1970|beta-lactamase_P25L|0.958343638 -MSIQHFRVALIPFFAAFCLPVFAHLETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1971|beta-lactamase_K32N|0.958126964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVNDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1972|beta-lactamase_R91K|0.957894263 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGKRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1973|beta-lactamase_T139M|0.957798485 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTMIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1974|beta-lactamase_Y95W|0.957661562 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHWSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1975|beta-lactamase_E145Y|0.957450068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKYLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1976|beta-lactamase_S201G|0.957329173 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAGRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1977|beta-lactamase_H285S|0.957329173 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKSW ->1978|beta-lactamase_E87D|0.957230659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQDQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1979|beta-lactamase_P60F|0.957079857 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRFEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1980|beta-lactamase_I140L|0.956819889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTLGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1981|beta-lactamase_F58S|0.956819889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESSRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1982|beta-lactamase_I3C|0.956819889 -MSCQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1983|beta-lactamase_S221Y|0.956749717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRYALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1984|beta-lactamase_E119A|0.956730854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRALCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1985|beta-lactamase_F13C|0.956685799 -MSIQHFRVALIPCFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1986|beta-lactamase_L38I|0.956436875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQIGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1987|beta-lactamase_C18G|0.956436875 -MSIQHFRVALIPFFAAFGLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1988|beta-lactamase_S201A|0.956388399 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAARQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1989|beta-lactamase_D99A|0.956361229 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNALVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1990|beta-lactamase_D83E|0.956287637 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVEAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1991|beta-lactamase_D207F|0.956265452 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIFWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1992|beta-lactamase_E237V|0.956244244 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGVRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1993|beta-lactamase_A183M|0.955969224 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAMMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1994|beta-lactamase_R118V|0.955969224 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVVELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1995|beta-lactamase_G226R|0.955592269 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPARWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1996|beta-lactamase_R81H|0.955486425 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSHVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1997|beta-lactamase_A34I|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDIEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1998|beta-lactamase_V106A|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPATEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->1999|beta-lactamase_G216T|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVATPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2000|beta-lactamase_K190C|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRCLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2001|beta-lactamase_E26Q|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPQTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2002|beta-lactamase_H151F|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLFNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2003|beta-lactamase_N50W|0.955334646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLWSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2004|beta-lactamase_F6C|0.955334646 -MSIQHCRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2005|beta-lactamase_E26V|0.954994146 -MSIQHFRVALIPFFAAFCLPVFAHPVTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2006|beta-lactamase_L219V|0.954923974 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLVRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2007|beta-lactamase_R81F|0.954923974 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSFVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2008|beta-lactamase_V8P|0.954923974 -MSIQHFRPALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2009|beta-lactamase_R189T|0.954893774 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLTKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2010|beta-lactamase_R41Q|0.954849013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAQVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2011|beta-lactamase_V42M|0.954709451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARMGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2012|beta-lactamase_R81Q|0.954636542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSQVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2013|beta-lactamase_K53D|0.954636542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGDILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2014|beta-lactamase_T126V|0.954365041 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIVMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2015|beta-lactamase_S57V|0.954260663 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEVFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2016|beta-lactamase_F17W|0.954260663 -MSIQHFRVALIPFFAAWCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2017|beta-lactamase_L10S|0.954260663 -MSIQHFRVASIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2018|beta-lactamase_G242A|0.954233688 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRAIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2019|beta-lactamase_R63K|0.954131069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEKFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2020|beta-lactamase_F22A|0.954131069 -MSIQHFRVALIPFFAAFCLPVAAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2021|beta-lactamase_A245S|0.953884783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIISALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2022|beta-lactamase_K213F|0.953659216 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADFVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2023|beta-lactamase_R92S|0.953637617 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRSIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2024|beta-lactamase_V82A|0.953589435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRADAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2025|beta-lactamase_A133S|0.95350128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTASNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2026|beta-lactamase_T158T|0.953491908 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2027|beta-lactamase_R189L|0.953478411 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLLKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2028|beta-lactamase_G85A|0.953421042 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAAQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2029|beta-lactamase_A183I|0.953320866 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAIMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2030|beta-lactamase_L223A|0.953062852 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAAPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2031|beta-lactamase_E270H|0.953007633 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDHRNRQIAEIGASLIKHW ->2032|beta-lactamase_V29S|0.953007633 -MSIQHFRVALIPFFAAFCLPVFAHPETLSKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2033|beta-lactamase_Q97N|0.953007633 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSNNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2034|beta-lactamase_A276V|0.952731538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIVEIGASLIKHW ->2035|beta-lactamase_I229V|0.952572136 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFVADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2036|beta-lactamase_L135M|0.95254223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANMLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2037|beta-lactamase_G226E|0.952521413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAEWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2038|beta-lactamase_T267L|0.952468344 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQALMDERNRQIAEIGASLIKHW ->2039|beta-lactamase_P60L|0.95246209 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRLEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2040|beta-lactamase_L205I|0.952445964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQIIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2041|beta-lactamase_F6N|0.952299462 -MSIQHNRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2042|beta-lactamase_P25K|0.952193227 -MSIQHFRVALIPFFAAFCLPVFAHKETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2043|beta-lactamase_T198L|0.952119146 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLLLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2044|beta-lactamase_T261S|0.952049462 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYSTGSQATMDERNRQIAEIGASLIKHW ->2045|beta-lactamase_Q265C|0.952049462 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSCATMDERNRQIAEIGASLIKHW ->2046|beta-lactamase_E210S|0.951892015 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMSADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2047|beta-lactamase_D99S|0.951672508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNSLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2048|beta-lactamase_P20H|0.951672508 -MSIQHFRVALIPFFAAFCLHVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2049|beta-lactamase_A77S|0.951526886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGSVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2050|beta-lactamase_T198M|0.951526886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLMLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2051|beta-lactamase_R273I|0.951526886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNIQIAEIGASLIKHW ->2052|beta-lactamase_F22N|0.951526886 -MSIQHFRVALIPFFAAFCLPVNAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2053|beta-lactamase_R7N|0.951526886 -MSIQHFNVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2054|beta-lactamase_R202A|0.951431304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASAQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2055|beta-lactamase_F149Y|0.951378821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAYLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2056|beta-lactamase_R118I|0.951378821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVIELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2057|beta-lactamase_L111Q|0.95097157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHQTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2058|beta-lactamase_L111Y|0.95097157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHYTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2059|beta-lactamase_K284W|0.95097157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIWHW ->2060|beta-lactamase_V21S|0.95097157 -MSIQHFRVALIPFFAAFCLPSFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2061|beta-lactamase_P253L|0.950911073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKLSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2062|beta-lactamase_R238T|0.95088791 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGETGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2063|beta-lactamase_S221L|0.950791644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRLALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2064|beta-lactamase_E46K|0.950501671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIKLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2065|beta-lactamase_L160F|0.950416253 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRFDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2066|beta-lactamase_A182D|0.950292914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPDAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2067|beta-lactamase_R92Q|0.950292914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRQIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2068|beta-lactamase_E61I|0.950292914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPIERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2069|beta-lactamase_K284C|0.950292914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLICHW ->2070|beta-lactamase_A77T|0.950098915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGTVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2071|beta-lactamase_R81A|0.950007144 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSAVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2072|beta-lactamase_R91R|0.949938399 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2073|beta-lactamase_V117M|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTMRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2074|beta-lactamase_L28A|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETAVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2075|beta-lactamase_A280F|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGFSLIKHW ->2076|beta-lactamase_G39M|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLMARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2077|beta-lactamase_G39Y|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLYARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2078|beta-lactamase_A84Y|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDYGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2079|beta-lactamase_D269W|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMWERNRQIAEIGASLIKHW ->2080|beta-lactamase_P25W|0.949749912 -MSIQHFRVALIPFFAAFCLPVFAHWETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2081|beta-lactamase_Q4F|0.949749912 -MSIFHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2082|beta-lactamase_V21T|0.949502453 -MSIQHFRVALIPFFAAFCLPTFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2083|beta-lactamase_T147G|0.9491125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELGAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2084|beta-lactamase_L160T|0.949051808 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRTDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2085|beta-lactamase_A34T|0.948935506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDTEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2086|beta-lactamase_R41A|0.948935506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAAVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2087|beta-lactamase_G90L|0.948861425 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLLRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2088|beta-lactamase_S221G|0.948857125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRGALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2089|beta-lactamase_P172N|0.948468149 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAINNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2090|beta-lactamase_H151I|0.948353704 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLINMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2091|beta-lactamase_K53W|0.948353704 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGWILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2092|beta-lactamase_R7A|0.948353704 -MSIQHFAVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2093|beta-lactamase_I278L|0.948224013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAELGASLIKHW ->2094|beta-lactamase_T262E|0.94816508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTEGSQATMDERNRQIAEIGASLIKHW ->2095|beta-lactamase_A183Y|0.948050244 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAYMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2096|beta-lactamase_E210G|0.948050244 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMGADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2097|beta-lactamase_A276G|0.94799571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIGEIGASLIKHW ->2098|beta-lactamase_T198T|0.947992129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2099|beta-lactamase_L19P|0.947842953 -MSIQHFRVALIPFFAAFCPPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2100|beta-lactamase_A200L|0.94774913 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLLSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2101|beta-lactamase_R271S|0.947578098 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDESNRQIAEIGASLIKHW ->2102|beta-lactamase_F14L|0.947578098 -MSIQHFRVALIPFLAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2103|beta-lactamase_A40Q|0.947168305 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGQRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2104|beta-lactamase_G251Y|0.947084451 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDYKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2105|beta-lactamase_Q4T|0.947084451 -MSITHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2106|beta-lactamase_I45Y|0.946957594 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYYELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2107|beta-lactamase_K30I|0.946742778 -MSIQHFRVALIPFFAAFCLPVFAHPETLVIVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2108|beta-lactamase_T139C|0.946742778 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTCIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2109|beta-lactamase_K213T|0.946742778 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADTVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2110|beta-lactamase_A9N|0.946742778 -MSIQHFRVNLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2111|beta-lactamase_T139H|0.946300538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTHIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2112|beta-lactamase_P217G|0.946300538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGGLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2113|beta-lactamase_D207H|0.946300538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIHWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2114|beta-lactamase_R202E|0.946026789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASEQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2115|beta-lactamase_I54C|0.946026789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKCLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2116|beta-lactamase_K32G|0.946026789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVGDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2117|beta-lactamase_R91H|0.945925635 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGHRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2118|beta-lactamase_T262M|0.945840608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTMGSQATMDERNRQIAEIGASLIKHW ->2119|beta-lactamase_A183N|0.945840608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPANMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2120|beta-lactamase_V214T|0.945791155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKTAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2121|beta-lactamase_P217V|0.945768188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGVLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2122|beta-lactamase_T262I|0.945705835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTIGSQATMDERNRQIAEIGASLIKHW ->2123|beta-lactamase_D99V|0.94561895 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNVLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2124|beta-lactamase_K144H|0.945523661 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPHELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2125|beta-lactamase_E108A|0.945459255 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTAKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2126|beta-lactamase_S80C|0.945406284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLCRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2127|beta-lactamase_E62E|0.945371886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2128|beta-lactamase_S122T|0.945361914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCTAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2129|beta-lactamase_P249R|0.94527542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGRDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2130|beta-lactamase_G234A|0.94526379 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSAAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2131|beta-lactamase_D250I|0.94525734 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPIGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2132|beta-lactamase_R176H|0.945115139 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEHDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2133|beta-lactamase_S254W|0.944863282 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPWRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2134|beta-lactamase_M127I|0.944863282 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITISDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2135|beta-lactamase_R59N|0.944863282 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFNPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2136|beta-lactamase_K109W|0.944863282 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEWHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2137|beta-lactamase_P60P|0.944754157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2138|beta-lactamase_T147T|0.944664992 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2139|beta-lactamase_V157G|0.944616507 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHGTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2140|beta-lactamase_D99N|0.944519165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNNLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2141|beta-lactamase_H5D|0.944295065 -MSIQDFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2142|beta-lactamase_S57C|0.944287441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILECFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2143|beta-lactamase_P217R|0.944217856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGRLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2144|beta-lactamase_G251C|0.944202903 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDCKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2145|beta-lactamase_D269P|0.943958376 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMPERNRQIAEIGASLIKHW ->2146|beta-lactamase_R92W|0.943958376 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRWIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2147|beta-lactamase_F149V|0.943897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAVLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2148|beta-lactamase_L137I|0.94372157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLITTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2149|beta-lactamase_P253F|0.943661659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKFSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2150|beta-lactamase_A84F|0.943577316 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDFGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2151|beta-lactamase_R159R|0.943542146 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2152|beta-lactamase_L137Y|0.94333621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLYTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2153|beta-lactamase_L150F|0.943316859 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFFHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2154|beta-lactamase_H285M|0.942983786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKMW ->2155|beta-lactamase_P60N|0.942882242 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRNEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2156|beta-lactamase_K252D|0.942827219 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGDPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2157|beta-lactamase_H24Y|0.94276897 -MSIQHFRVALIPFFAAFCLPVFAYPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2158|beta-lactamase_L188T|0.942759783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTTRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2159|beta-lactamase_T267I|0.9427332 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAIMDERNRQIAEIGASLIKHW ->2160|beta-lactamase_L136I|0.942683845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLILTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2161|beta-lactamase_G194K|0.942642113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTKELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2162|beta-lactamase_Q204Y|0.942642113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQYLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2163|beta-lactamase_N98P|0.942642113 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQPDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2164|beta-lactamase_R41L|0.942528939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGALVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2165|beta-lactamase_S57N|0.942506753 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILENFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2166|beta-lactamase_E56R|0.942504896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILRSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2167|beta-lactamase_R238A|0.942457985 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEAGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2168|beta-lactamase_I206E|0.942335721 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLEDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2169|beta-lactamase_G236A|0.942291351 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAAERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2170|beta-lactamase_K213Y|0.942263986 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADYVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2171|beta-lactamase_E237F|0.942148466 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGFRGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2172|beta-lactamase_K252W|0.942148466 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGWPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2173|beta-lactamase_F14C|0.942059431 -MSIQHFRVALIPFCAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2174|beta-lactamase_N272D|0.941931304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERDRQIAEIGASLIKHW ->2175|beta-lactamase_H151D|0.941931304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLDNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2176|beta-lactamase_A222Y|0.941862695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSYLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2177|beta-lactamase_A276N|0.941809138 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQINEIGASLIKHW ->2178|beta-lactamase_R92N|0.941809138 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRNIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2179|beta-lactamase_H94P|0.941605561 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIPYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2180|beta-lactamase_M184Y|0.94137286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAYATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2181|beta-lactamase_T126M|0.94137286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIMMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2182|beta-lactamase_G263D|0.94137286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTDSQATMDERNRQIAEIGASLIKHW ->2183|beta-lactamase_L111H|0.94137286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHHTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2184|beta-lactamase_R63T|0.94121854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEETFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2185|beta-lactamase_L47T|0.941062559 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIETDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2186|beta-lactamase_E145W|0.941062559 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKWLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2187|beta-lactamase_F58A|0.94092241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESARPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2188|beta-lactamase_V78I|0.940895534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAILSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2189|beta-lactamase_R41T|0.94084266 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGATVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2190|beta-lactamase_V72I|0.939976652 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKILLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2191|beta-lactamase_R189E|0.939719419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLEKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2192|beta-lactamase_Y103F|0.93955171 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEFSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2193|beta-lactamase_E145L|0.939013106 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKLLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2194|beta-lactamase_K30Q|0.938965608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVQVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2195|beta-lactamase_L111F|0.938965608 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHFTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2196|beta-lactamase_A9V|0.938932867 -MSIQHFRVVLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2197|beta-lactamase_N152I|0.938890745 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHIMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2198|beta-lactamase_V82T|0.938784803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRTDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2199|beta-lactamase_T261A|0.938754994 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYATGSQATMDERNRQIAEIGASLIKHW ->2200|beta-lactamase_A77D|0.938754994 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGDVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2201|beta-lactamase_G194R|0.938580444 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTRELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2202|beta-lactamase_A245G|0.938473036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIGALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2203|beta-lactamase_A182N|0.938433552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPNAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2204|beta-lactamase_V101E|0.938433552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLEEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2205|beta-lactamase_I54R|0.938433552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKRLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2206|beta-lactamase_P25D|0.938433552 -MSIQHFRVALIPFFAAFCLPVFAHDETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2207|beta-lactamase_R92A|0.938337676 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRAIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2208|beta-lactamase_A170N|0.938308063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNENIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2209|beta-lactamase_S221P|0.938255581 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRPALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2210|beta-lactamase_M127R|0.938234177 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITRSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2211|beta-lactamase_M67L|0.938199677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMLSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2212|beta-lactamase_R59K|0.938199677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFKPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2213|beta-lactamase_S57D|0.93790042 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEDFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2214|beta-lactamase_R41I|0.937677101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAIVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2215|beta-lactamase_K32K|0.937624898 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2216|beta-lactamase_T267V|0.937513497 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAVMDERNRQIAEIGASLIKHW ->2217|beta-lactamase_L10F|0.937476554 -MSIQHFRVAFIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2218|beta-lactamase_T262K|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTKGSQATMDERNRQIAEIGASLIKHW ->2219|beta-lactamase_L49A|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDANSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2220|beta-lactamase_R162S|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2221|beta-lactamase_A148W|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTWFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2222|beta-lactamase_L100V|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDVVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2223|beta-lactamase_G226A|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAAWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2224|beta-lactamase_G39T|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLTARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2225|beta-lactamase_S51K|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNKGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2226|beta-lactamase_R159T|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTTLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2227|beta-lactamase_Q203Y|0.936718931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRYQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2228|beta-lactamase_F17H|0.936718931 -MSIQHFRVALIPFFAAHCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2229|beta-lactamase_F6Q|0.936718931 -MSIQHQRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2230|beta-lactamase_L73P|0.936396315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVPLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2231|beta-lactamase_G226C|0.936386444 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPACWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2232|beta-lactamase_G251L|0.936228997 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDLKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2233|beta-lactamase_S57F|0.936067348 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEFFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2234|beta-lactamase_R41V|0.93586162 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAVVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2235|beta-lactamase_T193D|0.93570085 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLDGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2236|beta-lactamase_I140V|0.935650811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTVGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2237|beta-lactamase_H5L|0.935571843 -MSIQLFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2238|beta-lactamase_A77R|0.935465901 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGRVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2239|beta-lactamase_T147Q|0.935302492 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELQAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2240|beta-lactamase_G216S|0.935203685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVASPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2241|beta-lactamase_M180L|0.935144556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTLPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2242|beta-lactamase_V257L|0.934957985 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRILVIYTTGSQATMDERNRQIAEIGASLIKHW ->2243|beta-lactamase_S2R|0.934532457 -MRIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2244|beta-lactamase_K213E|0.934526202 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADEVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2245|beta-lactamase_E102G|0.934487598 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVGYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2246|beta-lactamase_P165V|0.934391918 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEVELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2247|beta-lactamase_F22K|0.934391918 -MSIQHFRVALIPFFAAFCLPVKAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2248|beta-lactamase_R238V|0.934354388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEVGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2249|beta-lactamase_A170H|0.934260174 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEHIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2250|beta-lactamase_P249Q|0.934147 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGQDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2251|beta-lactamase_T179S|0.934112695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTSMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2252|beta-lactamase_T107C|0.934004115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVCEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2253|beta-lactamase_L219F|0.933946355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLFRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2254|beta-lactamase_S221D|0.933946355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRDALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2255|beta-lactamase_L197M|0.93375734 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELMTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2256|beta-lactamase_A215S|0.933461112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVSGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2257|beta-lactamase_P172W|0.933461112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIWNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2258|beta-lactamase_Q265N|0.933394654 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSNATMDERNRQIAEIGASLIKHW ->2259|beta-lactamase_W163G|0.933330835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2260|beta-lactamase_S201N|0.933099208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLANRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2261|beta-lactamase_E210D|0.933099208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMDADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2262|beta-lactamase_E87V|0.933067934 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQVQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2263|beta-lactamase_V42V|0.932761764 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2264|beta-lactamase_D99H|0.932646706 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNHLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2265|beta-lactamase_E26D|0.932646706 -MSIQHFRVALIPFFAAFCLPVFAHPDTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2266|beta-lactamase_K32Y|0.932646706 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVYDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2267|beta-lactamase_R41S|0.932564709 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGASVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2268|beta-lactamase_E108L|0.932158043 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTLKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2269|beta-lactamase_F17L|0.932065002 -MSIQHFRVALIPFFAALCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2270|beta-lactamase_R81L|0.931965119 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSLVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2271|beta-lactamase_P25I|0.931928079 -MSIQHFRVALIPFFAAFCLPVFAHIETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2272|beta-lactamase_L282T|0.93179438 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASTIKHW ->2273|beta-lactamase_H5P|0.931782946 -MSIQPFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2274|beta-lactamase_M268V|0.931778254 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATVDERNRQIAEIGASLIKHW ->2275|beta-lactamase_L28T|0.931707007 -MSIQHFRVALIPFFAAFCLPVFAHPETTVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2276|beta-lactamase_A16P|0.931707007 -MSIQHFRVALIPFFAPFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2277|beta-lactamase_A215G|0.931653841 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVGGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2278|beta-lactamase_I206G|0.931400127 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLGDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2279|beta-lactamase_L74M|0.931289298 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLMCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2280|beta-lactamase_E145P|0.931053274 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKPLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2281|beta-lactamase_R238P|0.930428079 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEPGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2282|beta-lactamase_M268A|0.930350381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATADERNRQIAEIGASLIKHW ->2283|beta-lactamase_M184F|0.930203391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAFATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2284|beta-lactamase_Q274G|0.930203391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRGIAEIGASLIKHW ->2285|beta-lactamase_M153Q|0.930203391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNQGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2286|beta-lactamase_K32C|0.930203391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVCDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2287|beta-lactamase_S2P|0.930203391 -MPIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2288|beta-lactamase_R59H|0.930020729 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFHPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2289|beta-lactamase_L219M|0.929879408 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLMRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2290|beta-lactamase_N173I|0.929808552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPIDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2291|beta-lactamase_T126Q|0.929675147 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIQMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2292|beta-lactamase_G90C|0.929656675 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLCRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2293|beta-lactamase_D83Q|0.92942153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVQAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2294|beta-lactamase_G154Q|0.929201046 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMQDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2295|beta-lactamase_F6I|0.929201046 -MSIQHIRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2296|beta-lactamase_D113V|0.928807183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTVGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2297|beta-lactamase_S221F|0.928747762 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRFALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2298|beta-lactamase_A34F|0.928574482 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDFEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2299|beta-lactamase_T27I|0.928574482 -MSIQHFRVALIPFFAAFCLPVFAHPEILVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2300|beta-lactamase_A211F|0.928574482 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEFDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2301|beta-lactamase_R81S|0.928574482 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSSVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2302|beta-lactamase_F14Y|0.928574482 -MSIQHFRVALIPFYAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2303|beta-lactamase_T107T|0.928523846 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2304|beta-lactamase_G154E|0.928354388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMEDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2305|beta-lactamase_L55R|0.928354388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIRESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2306|beta-lactamase_L38T|0.928145827 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQTGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2307|beta-lactamase_L10Y|0.928145827 -MSIQHFRVAYIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2308|beta-lactamase_A246S|0.928065491 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIASLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2309|beta-lactamase_R7S|0.928065491 -MSIQHFSVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2310|beta-lactamase_K190I|0.927834158 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRILLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2311|beta-lactamase_V106C|0.927793501 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPCTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2312|beta-lactamase_I244L|0.927595006 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGILAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2313|beta-lactamase_G279C|0.927411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEICASLIKHW ->2314|beta-lactamase_E46L|0.927411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYILLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2315|beta-lactamase_A40M|0.927411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGMRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2316|beta-lactamase_G194F|0.927411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTFELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2317|beta-lactamase_E119H|0.927411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRHLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2318|beta-lactamase_K109C|0.927411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTECHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2319|beta-lactamase_P253S|0.927354486 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKSSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2320|beta-lactamase_F6R|0.927137226 -MSIQHRRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2321|beta-lactamase_I278V|0.927093735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEVGASLIKHW ->2322|beta-lactamase_H285L|0.926480268 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKLW ->2323|beta-lactamase_I125C|0.92645476 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAACTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2324|beta-lactamase_K144W|0.926389474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPWELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2325|beta-lactamase_V42W|0.926179154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARWGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2326|beta-lactamase_M268W|0.926179154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATWDERNRQIAEIGASLIKHW ->2327|beta-lactamase_I54Y|0.926179154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKYLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2328|beta-lactamase_F58R|0.926112305 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESRRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2329|beta-lactamase_A77E|0.925859763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGEVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2330|beta-lactamase_R162D|0.925859763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDDWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2331|beta-lactamase_R159Q|0.925859763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTQLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2332|beta-lactamase_R7F|0.925859763 -MSIQHFFVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2333|beta-lactamase_T187C|0.925665764 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATCLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2334|beta-lactamase_L191V|0.925556011 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKVLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2335|beta-lactamase_M184V|0.925520338 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAVATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2336|beta-lactamase_A170I|0.925485252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEIIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2337|beta-lactamase_I278M|0.925371687 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEMGASLIKHW ->2338|beta-lactamase_L28K|0.925316761 -MSIQHFRVALIPFFAAFCLPVFAHPETKVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2339|beta-lactamase_K32T|0.925316761 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVTDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2340|beta-lactamase_F17C|0.925316761 -MSIQHFRVALIPFFAACCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2341|beta-lactamase_P25C|0.925159118 -MSIQHFRVALIPFFAAFCLPVFAHCETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2342|beta-lactamase_C75G|0.925098915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLGGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2343|beta-lactamase_T126I|0.92508406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIIMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2344|beta-lactamase_I283T|0.924913321 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLTKHW ->2345|beta-lactamase_V258A|0.924872566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVAIYTTGSQATMDERNRQIAEIGASLIKHW ->2346|beta-lactamase_E46F|0.924872566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIFLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2347|beta-lactamase_P165C|0.924872566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWECELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2348|beta-lactamase_R189V|0.924662637 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLVKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2349|beta-lactamase_P253G|0.924533434 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKGSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2350|beta-lactamase_D99T|0.924502355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNTLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2351|beta-lactamase_M127C|0.924435604 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITCSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2352|beta-lactamase_P172F|0.924339435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIFNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2353|beta-lactamase_L188C|0.924293989 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTCRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2354|beta-lactamase_A123S|0.924189122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSSAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2355|beta-lactamase_S264A|0.924189122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGAQATMDERNRQIAEIGASLIKHW ->2356|beta-lactamase_I283C|0.924189122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLCKHW ->2357|beta-lactamase_K190W|0.924189122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRWLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2358|beta-lactamase_W163H|0.924189122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRHEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2359|beta-lactamase_T198R|0.923751183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLRLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2360|beta-lactamase_I244C|0.923715217 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGICAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2361|beta-lactamase_H5E|0.923687852 -MSIQEFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2362|beta-lactamase_H285A|0.92363449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKAW ->2363|beta-lactamase_L150A|0.923437265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFAHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2364|beta-lactamase_A183R|0.923358982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPARMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2365|beta-lactamase_D250P|0.923304642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPPGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2366|beta-lactamase_H285V|0.922936093 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKVW ->2367|beta-lactamase_A222D|0.922852043 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSDLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2368|beta-lactamase_A34Q|0.922757144 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDQEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2369|beta-lactamase_M66F|0.92255474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPFMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2370|beta-lactamase_A9R|0.922438341 -MSIQHFRVRLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2371|beta-lactamase_L38Y|0.92228578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQYGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2372|beta-lactamase_Q4L|0.922240041 -MSILHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2373|beta-lactamase_G234S|0.92212413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSSAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2374|beta-lactamase_V29R|0.921910975 -MSIQHFRVALIPFFAAFCLPVFAHPETLRKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2375|beta-lactamase_T147E|0.921826339 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELEAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2376|beta-lactamase_E46V|0.921750889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIVLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2377|beta-lactamase_S57L|0.921636738 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILELFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2378|beta-lactamase_P253V|0.921033434 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKVSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2379|beta-lactamase_L150T|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFTHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2380|beta-lactamase_V72T|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKTLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2381|beta-lactamase_Y44M|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGMIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2382|beta-lactamase_A266D|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQDTMDERNRQIAEIGASLIKHW ->2383|beta-lactamase_P60Y|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRYEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2384|beta-lactamase_R202C|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASCQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2385|beta-lactamase_G39I|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLIARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2386|beta-lactamase_D99I|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNILVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2387|beta-lactamase_H24W|0.920430131 -MSIQHFRVALIPFFAAFCLPVFAWPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2388|beta-lactamase_H5C|0.920430131 -MSIQCFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2389|beta-lactamase_R7I|0.920430131 -MSIQHFIVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2390|beta-lactamase_S2W|0.920430131 -MWIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2391|beta-lactamase_P217L|0.919952609 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGLLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2392|beta-lactamase_G194L|0.919601847 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTLELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2393|beta-lactamase_G226Q|0.919177101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAQWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2394|beta-lactamase_S51G|0.918853802 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNGGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2395|beta-lactamase_V82S|0.91884354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRSDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2396|beta-lactamase_D99L|0.918705444 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNLLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2397|beta-lactamase_I140Y|0.918475479 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTYGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2398|beta-lactamase_T147C|0.918475479 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELCAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2399|beta-lactamase_H285K|0.918394068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKKW ->2400|beta-lactamase_H110Q|0.918394068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKQLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2401|beta-lactamase_V78M|0.918305522 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAMLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2402|beta-lactamase_R202V|0.918103118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASVQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2403|beta-lactamase_S221W|0.9178582 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRWALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2404|beta-lactamase_R176C|0.9178582 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDECDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2405|beta-lactamase_D113C|0.9178582 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTCGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2406|beta-lactamase_A276E|0.91755562 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIEEIGASLIKHW ->2407|beta-lactamase_L100F|0.91755562 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDFVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2408|beta-lactamase_F17G|0.91755562 -MSIQHFRVALIPFFAAGCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2409|beta-lactamase_T147D|0.917277473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELDAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2410|beta-lactamase_L137F|0.91717241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLFTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2411|beta-lactamase_L111W|0.91717241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHWTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2412|beta-lactamase_P253R|0.917145045 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKRSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2413|beta-lactamase_T187A|0.917076534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATALRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2414|beta-lactamase_L282A|0.916939709 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASAIKHW ->2415|beta-lactamase_R176S|0.916881167 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDESDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2416|beta-lactamase_E62A|0.91667114 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEARFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2417|beta-lactamase_A200F|0.91667114 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLFSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2418|beta-lactamase_P25Y|0.91667114 -MSIQHFRVALIPFFAAFCLPVFAHYETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2419|beta-lactamase_R7Y|0.916357907 -MSIQHFYVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2420|beta-lactamase_M268H|0.916086503 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATHDERNRQIAEIGASLIKHW ->2421|beta-lactamase_F70C|0.915987695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTCKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2422|beta-lactamase_L73T|0.915987695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVTLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2423|beta-lactamase_W163Q|0.915987695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRQEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2424|beta-lactamase_V82H|0.91589612 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRHDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2425|beta-lactamase_M127S|0.915662735 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2426|beta-lactamase_R63Q|0.915639279 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEQFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2427|beta-lactamase_R63L|0.915597156 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEELFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2428|beta-lactamase_F228A|0.915514572 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWAIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2429|beta-lactamase_H285G|0.915418208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKGW ->2430|beta-lactamase_L47C|0.91537501 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIECDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2431|beta-lactamase_P25N|0.91537501 -MSIQHFRVALIPFFAAFCLPVFAHNETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2432|beta-lactamase_S240E|0.915286269 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGERGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2433|beta-lactamase_L111K|0.914321843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHKTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2434|beta-lactamase_R176F|0.914321843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEFDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2435|beta-lactamase_G216W|0.913914591 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAWPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2436|beta-lactamase_P165L|0.913723036 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWELELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2437|beta-lactamase_V31A|0.913689904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKAKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2438|beta-lactamase_F13S|0.913588849 -MSIQHFRVALIPSFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2439|beta-lactamase_E46H|0.913449189 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIHLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2440|beta-lactamase_T116L|0.913449189 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMLVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2441|beta-lactamase_G216C|0.912714435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVACPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2442|beta-lactamase_E62Y|0.912714435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEYRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2443|beta-lactamase_L146I|0.912518481 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEITAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2444|beta-lactamase_V106Y|0.912433845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPYTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2445|beta-lactamase_H94C|0.91228578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRICYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2446|beta-lactamase_F149T|0.912160487 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTATLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2447|beta-lactamase_S254F|0.911861132 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPFRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2448|beta-lactamase_Q4V|0.911545358 -MSIVHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2449|beta-lactamase_H24C|0.911380776 -MSIQHFRVALIPFFAAFCLPVFACPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2450|beta-lactamase_M127K|0.911185115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITKSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2451|beta-lactamase_H5R|0.911122273 -MSIQRFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2452|beta-lactamase_A170R|0.911084158 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNERIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2453|beta-lactamase_A123C|0.910656871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSCAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2454|beta-lactamase_R81M|0.910656871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSMVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2455|beta-lactamase_I54W|0.910656871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKWLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2456|beta-lactamase_E195C|0.910656871 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGCLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2457|beta-lactamase_F6W|0.910656871 -MSIQHWRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2458|beta-lactamase_H5I|0.910656871 -MSIQIFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2459|beta-lactamase_F149A|0.910304642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAALHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2460|beta-lactamase_F149L|0.910174267 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTALLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2461|beta-lactamase_Q204D|0.910064513 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQDLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2462|beta-lactamase_E119S|0.910064513 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRSLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2463|beta-lactamase_L38F|0.910016038 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQFGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2464|beta-lactamase_L47A|0.909703391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEADLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2465|beta-lactamase_G85M|0.909663028 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAMQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2466|beta-lactamase_I3M|0.909570964 -MSMQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2467|beta-lactamase_S2C|0.909460135 -MCIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2468|beta-lactamase_L137V|0.909199971 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLVTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2469|beta-lactamase_L49T|0.909153254 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDTNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2470|beta-lactamase_I11L|0.909107418 -MSIQHFRVALLPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2471|beta-lactamase_R159S|0.908993364 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTSLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2472|beta-lactamase_T27L|0.90879526 -MSIQHFRVALIPFFAAFCLPVFAHPELLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2473|beta-lactamase_I171P|0.90879526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAPPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2474|beta-lactamase_E270G|0.908634783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDGRNRQIAEIGASLIKHW ->2475|beta-lactamase_I206H|0.908213556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLHDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2476|beta-lactamase_P253N|0.908213556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKNSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2477|beta-lactamase_R176N|0.908213556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDENDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2478|beta-lactamase_E108F|0.908213556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTFKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2479|beta-lactamase_R92P|0.908213556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRPIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2480|beta-lactamase_F6H|0.908213556 -MSIQHHRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2481|beta-lactamase_P25F|0.908213556 -MSIQHFRVALIPFFAAFCLPVFAHFETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2482|beta-lactamase_P25R|0.907864552 -MSIQHFRVALIPFFAAFCLPVFAHRETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2483|beta-lactamase_L73F|0.907761054 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVFLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2484|beta-lactamase_R91T|0.907761054 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGTRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2485|beta-lactamase_M127A|0.907620514 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITASDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2486|beta-lactamase_F58V|0.90739915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESVRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2487|beta-lactamase_F58T|0.907102922 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESTRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2488|beta-lactamase_R41F|0.907102922 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAFVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2489|beta-lactamase_A170P|0.906828196 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEPIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2490|beta-lactamase_G85Y|0.906747566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAYQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2491|beta-lactamase_A23S|0.906747566 -MSIQHFRVALIPFFAAFCLPVFSHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2492|beta-lactamase_V101L|0.906468344 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLLEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2493|beta-lactamase_E62H|0.906468344 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEHRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2494|beta-lactamase_R7V|0.906388106 -MSIQHFVVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2495|beta-lactamase_I244M|0.90619352 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIMAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2496|beta-lactamase_P249A|0.905996296 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGADGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2497|beta-lactamase_R81Y|0.90577024 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSYVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2498|beta-lactamase_L19R|0.905622176 -MSIQHFRVALIPFFAAFCRPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2499|beta-lactamase_T187M|0.905527668 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATMLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2500|beta-lactamase_P253Q|0.905347938 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKQSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2501|beta-lactamase_H110C|0.905072136 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKCLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2502|beta-lactamase_R92E|0.905072136 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGREIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2503|beta-lactamase_A15H|0.905072136 -MSIQHFRVALIPFFHAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2504|beta-lactamase_R162G|0.904998642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDGWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2505|beta-lactamase_P12K|0.904935897 -MSIQHFRVALIKFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2506|beta-lactamase_Q4P|0.904935897 -MSIPHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2507|beta-lactamase_S2A|0.904834548 -MAIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2508|beta-lactamase_A40T|0.904642602 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGTRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2509|beta-lactamase_T262A|0.904445866 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTAGSQATMDERNRQIAEIGASLIKHW ->2510|beta-lactamase_T131C|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNCAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2511|beta-lactamase_E56H|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILHSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2512|beta-lactamase_V101R|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLREYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2513|beta-lactamase_F58C|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESCRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2514|beta-lactamase_V214K|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKKAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2515|beta-lactamase_W227F|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGFFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2516|beta-lactamase_H110N|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKNLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2517|beta-lactamase_S51A|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNAGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2518|beta-lactamase_E270N|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDNRNRQIAEIGASLIKHW ->2519|beta-lactamase_E277H|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAHIGASLIKHW ->2520|beta-lactamase_E195V|0.904141331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGVLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2521|beta-lactamase_V42C|0.90377112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARCGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2522|beta-lactamase_S104A|0.903210624 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYAPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2523|beta-lactamase_R176A|0.903210624 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEADTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2524|beta-lactamase_N50C|0.903183161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLCSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2525|beta-lactamase_I283A|0.90309051 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLAKHW ->2526|beta-lactamase_G85L|0.903017993 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDALQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2527|beta-lactamase_E87F|0.902977922 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQFQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2528|beta-lactamase_R189D|0.902876183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLDKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2529|beta-lactamase_G216D|0.90272499 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVADPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2530|beta-lactamase_A170T|0.902716097 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNETIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2531|beta-lactamase_H5V|0.902660584 -MSIQVFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2532|beta-lactamase_V106H|0.902590022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPHTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2533|beta-lactamase_L28R|0.90251252 -MSIQHFRVALIPFFAAFCLPVFAHPETRVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2534|beta-lactamase_F17N|0.90242671 -MSIQHFRVALIPFFAANCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2535|beta-lactamase_K32F|0.902105268 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVFDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2536|beta-lactamase_L111R|0.901993364 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHRTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2537|beta-lactamase_D99K|0.901940197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNKLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2538|beta-lactamase_R63H|0.901635369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEHFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2539|beta-lactamase_Y260I|0.901426613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIITTGSQATMDERNRQIAEIGASLIKHW ->2540|beta-lactamase_E277F|0.901426613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAFIGASLIKHW ->2541|beta-lactamase_R271C|0.901308552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDECNRQIAEIGASLIKHW ->2542|beta-lactamase_P249S|0.901284705 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGSDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2543|beta-lactamase_M268Q|0.90115257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATQDERNRQIAEIGASLIKHW ->2544|beta-lactamase_M268T|0.901110936 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATTDERNRQIAEIGASLIKHW ->2545|beta-lactamase_A16Y|0.90088361 -MSIQHFRVALIPFFAYFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2546|beta-lactamase_P249M|0.9005781959999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGMDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2547|beta-lactamase_P165I|0.900439416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEIELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2548|beta-lactamase_V214A|0.900382437 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKAAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2549|beta-lactamase_H110G|0.9003087470000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKGLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2550|beta-lactamase_P249N|0.900232027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGNDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2551|beta-lactamase_P165N|0.899854877 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWENELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2552|beta-lactamase_A34L|0.8997241109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDLEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2553|beta-lactamase_Q203F|0.899487402 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRFQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2554|beta-lactamase_E210L|0.899487402 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMLADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2555|beta-lactamase_E108Y|0.899487402 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTYKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2556|beta-lactamase_F6S|0.899487402 -MSIQHSRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2557|beta-lactamase_P181C|0.899240334 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMCAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2558|beta-lactamase_A185S|0.899224013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMSTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2559|beta-lactamase_D48S|0.899224013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELSLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2560|beta-lactamase_L167T|0.899129408 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPETNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2561|beta-lactamase_P253T|0.898711796 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKTSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2562|beta-lactamase_A9Q|0.898711796 -MSIQHFRVQLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2563|beta-lactamase_L89F|0.8985657840000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQFGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2564|beta-lactamase_F70W|0.8982181490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTWKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2565|beta-lactamase_A211V|0.8981655690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2566|beta-lactamase_A170L|0.898131949 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNELIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2567|beta-lactamase_A183C|0.897876476 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPACMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2568|beta-lactamase_W163D|0.897784803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRDEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2569|beta-lactamase_L28S|0.8976258890000001 -MSIQHFRVALIPFFAAFCLPVFAHPETSVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2570|beta-lactamase_G154D|0.8976258890000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMDDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2571|beta-lactamase_T187V|0.897578978 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATVLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2572|beta-lactamase_A132S|0.897492875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTSANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2573|beta-lactamase_A183K|0.897379994 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAKMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2574|beta-lactamase_A222F|0.897339435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSFLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2575|beta-lactamase_L55H|0.8972829459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIHESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2576|beta-lactamase_M268Y|0.8972829459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATYDERNRQIAEIGASLIKHW ->2577|beta-lactamase_L55K|0.8971604870000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIKESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2578|beta-lactamase_G216L|0.896901886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVALPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2579|beta-lactamase_G251F|0.8967374020000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDFKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2580|beta-lactamase_I229M|0.896565197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFMADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2581|beta-lactamase_L38S|0.896476065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQSGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2582|beta-lactamase_T186P|0.896351065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAPTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2583|beta-lactamase_S281D|0.89599698 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGADLIKHW ->2584|beta-lactamase_A211W|0.89599698 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEWDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2585|beta-lactamase_H110W|0.89599698 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKWLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2586|beta-lactamase_E277Y|0.89599698 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAYIGASLIKHW ->2587|beta-lactamase_Q4W|0.89599698 -MSIWHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2588|beta-lactamase_E62V|0.895517895 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEVRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2589|beta-lactamase_T187G|0.895484373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATGLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2590|beta-lactamase_A276L|0.8952565579999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQILEIGASLIKHW ->2591|beta-lactamase_R238E|0.895164885 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEEGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2592|beta-lactamase_T126L|0.895154427 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAILMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2593|beta-lactamase_T147K|0.895092074 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELKAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2594|beta-lactamase_D161N|0.895019654 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLNRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2595|beta-lactamase_H110A|0.895019654 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKALTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2596|beta-lactamase_A235S|0.894970397 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGSGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2597|beta-lactamase_E87T|0.8949646309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQTQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2598|beta-lactamase_G263S|0.894934627 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTSSQATMDERNRQIAEIGASLIKHW ->2599|beta-lactamase_L192C|0.8948334729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLCTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2600|beta-lactamase_E56M|0.8948334729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILMSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2601|beta-lactamase_N272T|0.8947110140000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERTRQIAEIGASLIKHW ->2602|beta-lactamase_L28Q|0.894664298 -MSIQHFRVALIPFFAAFCLPVFAHPETQVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2603|beta-lactamase_G216H|0.8945597240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAHPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2604|beta-lactamase_T107V|0.894251769 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVVEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2605|beta-lactamase_L197I|0.894117484 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELITLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2606|beta-lactamase_A40C|0.894117484 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGCRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2607|beta-lactamase_I206N|0.894117484 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLNDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2608|beta-lactamase_L55T|0.894117484 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKITESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2609|beta-lactamase_V106S|0.893970885 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPSTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2610|beta-lactamase_L73C|0.8939611120000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVCLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2611|beta-lactamase_M209L|0.8939024729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWLEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2612|beta-lactamase_G251P|0.89377542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDPKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2613|beta-lactamase_R7W|0.893632731 -MSIQHFWVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2614|beta-lactamase_I11G|0.893397195 -MSIQHFRVALGPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2615|beta-lactamase_A124V|0.893371785 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAVITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2616|beta-lactamase_T262V|0.8932818709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTVGSQATMDERNRQIAEIGASLIKHW ->2617|beta-lactamase_K190F|0.8932818709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRFLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2618|beta-lactamase_L136V|0.8931137709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLVLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2619|beta-lactamase_T262R|0.893098133 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTRGSQATMDERNRQIAEIGASLIKHW ->2620|beta-lactamase_L73S|0.892851847 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVSLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2621|beta-lactamase_G52D|0.892844029 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSDKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2622|beta-lactamase_G216Y|0.892809822 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAYPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2623|beta-lactamase_V78V|0.892681318 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2624|beta-lactamase_A183F|0.8925068509999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAFMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2625|beta-lactamase_L10G|0.8925068509999999 -MSIQHFRVAGIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2626|beta-lactamase_E35Q|0.8921393759999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAQDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2627|beta-lactamase_L197L|0.891867759 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2628|beta-lactamase_P165P|0.891729387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2629|beta-lactamase_L282F|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASFIKHW ->2630|beta-lactamase_T262W|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTWGSQATMDERNRQIAEIGASLIKHW ->2631|beta-lactamase_A183W|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAWMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2632|beta-lactamase_A266Y|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQYTMDERNRQIAEIGASLIKHW ->2633|beta-lactamase_T139K|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTKIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2634|beta-lactamase_S122C|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCCAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2635|beta-lactamase_L55C|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKICESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2636|beta-lactamase_E108W|0.891110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTWKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2637|beta-lactamase_C18V|0.891110252 -MSIQHFRVALIPFFAAFVLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2638|beta-lactamase_T187I|0.890966585 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATILRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2639|beta-lactamase_P143H|0.8905668590000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGHKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2640|beta-lactamase_E56V|0.890463262 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILVSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2641|beta-lactamase_S201T|0.89030689 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLATRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2642|beta-lactamase_V72A|0.8902482509999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKALLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2643|beta-lactamase_S240C|0.890071355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGCRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2644|beta-lactamase_G39W|0.889888595 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLWARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2645|beta-lactamase_Q97C|0.889784998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSCNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2646|beta-lactamase_I243C|0.8896628320000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGCIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2647|beta-lactamase_R63I|0.8896628320000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEIFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2648|beta-lactamase_Y95V|0.889607125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHVSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2649|beta-lactamase_D161E|0.8893842940000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLERWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2650|beta-lactamase_L49C|0.889333473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDCNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2651|beta-lactamase_H110S|0.889333473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKSLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2652|beta-lactamase_M127N|0.8891556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITNSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2653|beta-lactamase_M67Q|0.888967953 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMQSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2654|beta-lactamase_E56L|0.888810604 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILLSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2655|beta-lactamase_P20S|0.888810604 -MSIQHFRVALIPFFAAFCLSVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2656|beta-lactamase_E56C|0.8885604090000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILCSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2657|beta-lactamase_K53C|0.8885604090000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGCILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2658|beta-lactamase_W208M|0.8885037240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDMMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2659|beta-lactamase_T187L|0.8884450840000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATLLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2660|beta-lactamase_L55Q|0.888377649 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIQESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2661|beta-lactamase_V8G|0.8880815190000001 -MSIQHFRGALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2662|beta-lactamase_S233A|0.888056108 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKAGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2663|beta-lactamase_L79L|0.8879909429999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2664|beta-lactamase_V31M|0.8878528240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKMKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2665|beta-lactamase_M153G|0.8878528240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNGGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2666|beta-lactamase_G194M|0.8878528240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTMELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2667|beta-lactamase_G154N|0.8878528240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMNDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2668|beta-lactamase_H156M|0.8878528240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDMVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2669|beta-lactamase_L19E|0.8878528240000001 -MSIQHFRVALIPFFAAFCEPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2670|beta-lactamase_R81R|0.887772883 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2671|beta-lactamase_R63S|0.8877609559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEESFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2672|beta-lactamase_Y44I|0.886847156 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGIIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2673|beta-lactamase_T107L|0.886767015 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVLEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2674|beta-lactamase_L167A|0.886745514 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEANEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2675|beta-lactamase_L188Y|0.886649736 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTYRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2676|beta-lactamase_D48A|0.886599892 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELALNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2677|beta-lactamase_G154S|0.886372176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMSDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2678|beta-lactamase_G85C|0.886315491 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDACQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2679|beta-lactamase_N168S|0.88597929 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELSEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2680|beta-lactamase_M153K|0.885936288 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNKGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2681|beta-lactamase_P253K|0.885898172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKKSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2682|beta-lactamase_L150Y|0.885709548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFYHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2683|beta-lactamase_N168A|0.8856802290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELAEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2684|beta-lactamase_V101Y|0.8855258109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLYEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2685|beta-lactamase_E277C|0.8855258109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIACIGASLIKHW ->2686|beta-lactamase_P249T|0.8853147090000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGTDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2687|beta-lactamase_K213G|0.8852805020000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADGVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2688|beta-lactamase_E62S|0.8851378129999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPESRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2689|beta-lactamase_G194Y|0.885043989 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTYELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2690|beta-lactamase_E102K|0.885013692 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2691|beta-lactamase_D99D|0.884888059 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2692|beta-lactamase_A266F|0.884594419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQFTMDERNRQIAEIGASLIKHW ->2693|beta-lactamase_P249E|0.884594419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGEDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2694|beta-lactamase_E61C|0.884594419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPCERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2695|beta-lactamase_Q4G|0.8845162329999999 -MSIGHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2696|beta-lactamase_M268S|0.88445173 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATSDERNRQIAEIGASLIKHW ->2697|beta-lactamase_L10P|0.884423387 -MSIQHFRVAPIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2698|beta-lactamase_A15Q|0.8843813620000001 -MSIQHFRVALIPFFQAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2699|beta-lactamase_R162T|0.884311972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDTWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2700|beta-lactamase_L74V|0.8842113079999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLVCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2701|beta-lactamase_G263A|0.8840940290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTASQATMDERNRQIAEIGASLIKHW ->2702|beta-lactamase_R238I|0.883973817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEIGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2703|beta-lactamase_A40N|0.883780307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGNRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2704|beta-lactamase_M153Y|0.883780307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNYGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2705|beta-lactamase_G194W|0.883780307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTWELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2706|beta-lactamase_V101F|0.883780307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLFEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2707|beta-lactamase_R202H|0.883780307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASHQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2708|beta-lactamase_Q4D|0.883780307 -MSIDHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2709|beta-lactamase_V8W|0.883780307 -MSIQHFRWALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2710|beta-lactamase_D174E|0.883573114 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNEERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2711|beta-lactamase_F58I|0.883482222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESIRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2712|beta-lactamase_G90P|0.883482222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLPRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2713|beta-lactamase_G43A|0.8833385559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVAYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2714|beta-lactamase_R63V|0.8833053259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEVFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2715|beta-lactamase_C121M|0.883291644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELMSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2716|beta-lactamase_R162Q|0.883233004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDQWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2717|beta-lactamase_S51Y|0.883061972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNYGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2718|beta-lactamase_E119N|0.883061972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRNLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2719|beta-lactamase_A211Y|0.882841097 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEYDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2720|beta-lactamase_M127H|0.882841097 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITHSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2721|beta-lactamase_F228I|0.88279223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWIIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2722|beta-lactamase_I3R|0.882467758 -MSRQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2723|beta-lactamase_L89L|0.882437861 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2724|beta-lactamase_T27C|0.8824228009999999 -MSIQHFRVALIPFFAAFCLPVFAHPECLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2725|beta-lactamase_M153E|0.8824228009999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNEGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2726|beta-lactamase_L28C|0.8824228009999999 -MSIQHFRVALIPFFAAFCLPVFAHPETCVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2727|beta-lactamase_S2V|0.8824228009999999 -MVIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2728|beta-lactamase_Q97Q|0.882314322 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2729|beta-lactamase_I54S|0.882253724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKSLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2730|beta-lactamase_D99R|0.881968344 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNRLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2731|beta-lactamase_L111S|0.881851065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHSTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2732|beta-lactamase_H110L|0.8814689309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKLLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2733|beta-lactamase_R176L|0.881385858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDELDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2734|beta-lactamase_F228K|0.881336992 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWKIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2735|beta-lactamase_E62N|0.881336992 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPENRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2736|beta-lactamase_R7E|0.881336992 -MSIQHFEVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2737|beta-lactamase_G216R|0.880955835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVARPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2738|beta-lactamase_A124C|0.880783825 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSACITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2739|beta-lactamase_A77G|0.8807623240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGGVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2740|beta-lactamase_S281G|0.8807525509999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAGLIKHW ->2741|beta-lactamase_C121A|0.880654818 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2742|beta-lactamase_D113L|0.880612793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTLGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2743|beta-lactamase_L55E|0.8804486020000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIEESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2744|beta-lactamase_T147I|0.8801876559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELIAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2745|beta-lactamase_A15A|0.879936917 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2746|beta-lactamase_R271G|0.879823114 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEGNRQIAEIGASLIKHW ->2747|beta-lactamase_G52N|0.879707789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSNKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2748|beta-lactamase_E270Y|0.879707789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDYRNRQIAEIGASLIKHW ->2749|beta-lactamase_F14S|0.879707789 -MSIQHFRVALIPFSAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2750|beta-lactamase_E87Q|0.879081323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQQQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2751|beta-lactamase_V21G|0.878967953 -MSIQHFRVALIPFFAAFCLPGFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2752|beta-lactamase_F17S|0.878802785 -MSIQHFRVALIPFFAASCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2753|beta-lactamase_I3D|0.878802785 -MSDQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2754|beta-lactamase_I259M|0.87875001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVMYTTGSQATMDERNRQIAEIGASLIKHW ->2755|beta-lactamase_L192W|0.878544771 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLWTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2756|beta-lactamase_R91N|0.878544771 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGNRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2757|beta-lactamase_P217Y|0.878382535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGYLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2758|beta-lactamase_F14F|0.878300658 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2759|beta-lactamase_M66C|0.8779837859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPCMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2760|beta-lactamase_Y95L|0.8779573979999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHLSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2761|beta-lactamase_P25G|0.8779378520000001 -MSIQHFRVALIPFFAAFCLPVFAHGETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2762|beta-lactamase_L55N|0.8779104870000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKINESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2763|beta-lactamase_T267Y|0.877869439 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAYMDERNRQIAEIGASLIKHW ->2764|beta-lactamase_H5A|0.877869439 -MSIQAFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2765|beta-lactamase_D48Q|0.8778020040000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELQLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2766|beta-lactamase_I259C|0.877578196 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVCYTTGSQATMDERNRQIAEIGASLIKHW ->2767|beta-lactamase_A170D|0.877446257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEDIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2768|beta-lactamase_G242S|0.8773758890000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRSIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2769|beta-lactamase_F228T|0.8773436379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWTIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2770|beta-lactamase_V257C|0.8773123629999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRICVIYTTGSQATMDERNRQIAEIGASLIKHW ->2771|beta-lactamase_F149H|0.8773123629999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAHLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2772|beta-lactamase_A183G|0.8771227620000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAGMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2773|beta-lactamase_L188A|0.877111034 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTARKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2774|beta-lactamase_R7L|0.877109079 -MSIQHFLVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2775|beta-lactamase_R92C|0.876953685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRCIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2776|beta-lactamase_A235A|0.876766673 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2777|beta-lactamase_T262D|0.876707398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDGSQATMDERNRQIAEIGASLIKHW ->2778|beta-lactamase_L111E|0.876707398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHETDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2779|beta-lactamase_E195Y|0.876707398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGYLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2780|beta-lactamase_S264N|0.8765754590000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGNQATMDERNRQIAEIGASLIKHW ->2781|beta-lactamase_T126D|0.8765754590000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIDMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2782|beta-lactamase_V101N|0.876450362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLNEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2783|beta-lactamase_I140M|0.876217758 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTMGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2784|beta-lactamase_P249D|0.876217758 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGDDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2785|beta-lactamase_K109P|0.876217758 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEPHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2786|beta-lactamase_I11T|0.875917719 -MSIQHFRVALTPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2787|beta-lactamase_D161D|0.8758931959999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2788|beta-lactamase_M268N|0.875850283 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATNDERNRQIAEIGASLIKHW ->2789|beta-lactamase_L192T|0.875322527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLTTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2790|beta-lactamase_D161S|0.875322527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLSRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2791|beta-lactamase_S57I|0.8750537629999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEIFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2792|beta-lactamase_A9L|0.8748582970000001 -MSIQHFRVLLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2793|beta-lactamase_A124M|0.874821159 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAMITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2794|beta-lactamase_M115I|0.8747947709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGITVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2795|beta-lactamase_G76T|0.874666742 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCTAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2796|beta-lactamase_T147A|0.8744888679999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELAAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2797|beta-lactamase_T198V|0.874438047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLVLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2798|beta-lactamase_F149K|0.874355952 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAKLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2799|beta-lactamase_R202G|0.874219126 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASGQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2800|beta-lactamase_T261Q|0.874007047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYQTGSQATMDERNRQIAEIGASLIKHW ->2801|beta-lactamase_C75S|0.873599502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLSGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2802|beta-lactamase_P181V|0.873568227 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMVAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2803|beta-lactamase_L111D|0.873518384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHDTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2804|beta-lactamase_G251W|0.873489064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDWKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2805|beta-lactamase_I3A|0.873461699 -MSAQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2806|beta-lactamase_P20T|0.873461699 -MSIQHFRVALIPFFAAFCLTVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2807|beta-lactamase_V214N|0.8734431290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKNAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2808|beta-lactamase_G85T|0.8733903540000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDATQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2809|beta-lactamase_M127D|0.8732486420000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITDSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2810|beta-lactamase_R63P|0.8731929340000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEPFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2811|beta-lactamase_T27S|0.87296033 -MSIQHFRVALIPFFAAFCLPVFAHPESLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2812|beta-lactamase_M153R|0.872866507 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNRGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2813|beta-lactamase_E46D|0.872673974 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIDLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2814|beta-lactamase_L47Q|0.872444302 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEQDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2815|beta-lactamase_V214S|0.8722029029999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKSAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2816|beta-lactamase_C75I|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLIGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2817|beta-lactamase_V78T|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGATLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2818|beta-lactamase_A170M|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEMIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2819|beta-lactamase_L192Y|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLYTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2820|beta-lactamase_S281W|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAWLIKHW ->2821|beta-lactamase_T139Y|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTYIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2822|beta-lactamase_V106F|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPFTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2823|beta-lactamase_V106W|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPWTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2824|beta-lactamase_F149Q|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAQLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2825|beta-lactamase_L28G|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETGVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2826|beta-lactamase_T147H|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELHAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2827|beta-lactamase_V101G|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLGEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2828|beta-lactamase_R63M|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEMFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2829|beta-lactamase_S51R|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNRGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2830|beta-lactamase_E62C|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPECRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2831|beta-lactamase_E62L|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPELRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2832|beta-lactamase_P217F|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGFLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2833|beta-lactamase_R159M|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTMLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2834|beta-lactamase_E270W|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDWRNRQIAEIGASLIKHW ->2835|beta-lactamase_R176Y|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEYDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2836|beta-lactamase_E26R|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPRTLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2837|beta-lactamase_E108C|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTCKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2838|beta-lactamase_D113I|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTIGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2839|beta-lactamase_D113W|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTWGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2840|beta-lactamase_Y103P|0.871563731 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEPSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2841|beta-lactamase_F22D|0.871563731 -MSIQHFRVALIPFFAAFCLPVDAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2842|beta-lactamase_R91S|0.871223622 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGSRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2843|beta-lactamase_V78L|0.8710301109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGALLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2844|beta-lactamase_L135Q|0.870894263 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANQLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2845|beta-lactamase_V82W|0.870294185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRWDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2846|beta-lactamase_M115Q|0.870243364 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGQTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2847|beta-lactamase_L38G|0.870052785 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQGGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2848|beta-lactamase_P217C|0.869849502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGCLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2849|beta-lactamase_V106D|0.8697429729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPDTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2850|beta-lactamase_M184L|0.869527961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAALATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2851|beta-lactamase_M67H|0.869358884 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMHSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2852|beta-lactamase_D212Q|0.8692904709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAQKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2853|beta-lactamase_V82Y|0.869057867 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRYDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2854|beta-lactamase_P165K|0.868885858 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEKELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2855|beta-lactamase_R7D|0.8686894159999999 -MSIQHFDVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2856|beta-lactamase_L49S|0.868232027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDSNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2857|beta-lactamase_P165A|0.8681792509999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEAELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2858|beta-lactamase_A200W|0.8680737 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLWSRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2859|beta-lactamase_A183P|0.8678528240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAPMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2860|beta-lactamase_R159N|0.8674912140000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTNLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2861|beta-lactamase_I256M|0.8674345290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRMVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2862|beta-lactamase_D99Y|0.867251769 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNYLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2863|beta-lactamase_M268G|0.867187265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATGDERNRQIAEIGASLIKHW ->2864|beta-lactamase_D212N|0.867121785 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEANKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2865|beta-lactamase_I229L|0.867042621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFLADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2866|beta-lactamase_M67I|0.867018188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMISTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2867|beta-lactamase_G251I|0.86700646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDIKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2868|beta-lactamase_I93I|0.8669936859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2869|beta-lactamase_E62Q|0.866909705 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEQRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2870|beta-lactamase_N173P|0.866909705 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPPDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2871|beta-lactamase_A34A|0.86672839 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2872|beta-lactamase_G251V|0.866725968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDVKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2873|beta-lactamase_L28N|0.866677101 -MSIQHFRVALIPFFAAFCLPVFAHPETNVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2874|beta-lactamase_T147M|0.866677101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELMAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2875|beta-lactamase_Y103H|0.866677101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEHSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2876|beta-lactamase_A222L|0.866594029 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSLLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2877|beta-lactamase_F70H|0.866420065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTHKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2878|beta-lactamase_Y95M|0.866420065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHMSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2879|beta-lactamase_R176W|0.866420065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEWDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2880|beta-lactamase_K30F|0.866281284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVFVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2881|beta-lactamase_G194V|0.86626076 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTVELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2882|beta-lactamase_L191C|0.8658151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKCLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2883|beta-lactamase_W286M|0.8658151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHM ->2884|beta-lactamase_G154A|0.865729095 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMADHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2885|beta-lactamase_P253D|0.8656147479999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKDSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2886|beta-lactamase_L38V|0.8655873829999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQVGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2887|beta-lactamase_G141H|0.865325459 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIHGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2888|beta-lactamase_S201C|0.8652580240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLACRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2889|beta-lactamase_S104C|0.865170065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYCPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2890|beta-lactamase_L137T|0.865047899 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2891|beta-lactamase_V21L|0.864860252 -MSIQHFRVALIPFFAAFCLPLFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2892|beta-lactamase_I54K|0.8648231140000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKKLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2893|beta-lactamase_P253W|0.864744928 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKWSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2894|beta-lactamase_H110E|0.864744928 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKELTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2895|beta-lactamase_L89Y|0.864705835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQYGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2896|beta-lactamase_D48N|0.864705835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELNLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2897|beta-lactamase_F228C|0.864482027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWCIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2898|beta-lactamase_I259F|0.864324677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVFYTTGSQATMDERNRQIAEIGASLIKHW ->2899|beta-lactamase_G154K|0.864324677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMKDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2900|beta-lactamase_E87E|0.86429389 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2901|beta-lactamase_R189I|0.8642904709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLIKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2902|beta-lactamase_T267F|0.8641096659999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAFMDERNRQIAEIGASLIKHW ->2903|beta-lactamase_L160N|0.86404614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRNDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2904|beta-lactamase_D48H|0.86404614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELHLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2905|beta-lactamase_V214I|0.86404614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKIAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2906|beta-lactamase_E62F|0.86404614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEFRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2907|beta-lactamase_R41D|0.86404614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGADVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2908|beta-lactamase_L89P|0.863960135 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQPGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2909|beta-lactamase_V214L|0.863956226 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKLAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2910|beta-lactamase_L38A|0.8639484070000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQAGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2911|beta-lactamase_L111P|0.86392886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHPTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2912|beta-lactamase_F13F|0.863613503 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2913|beta-lactamase_D99F|0.8633043490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNFLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2914|beta-lactamase_L74I|0.86324571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLICGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2915|beta-lactamase_F228V|0.8632105259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWVIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2916|beta-lactamase_M268P|0.8631059520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATPDERNRQIAEIGASLIKHW ->2917|beta-lactamase_F13P|0.863064904 -MSIQHFRVALIPPFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2918|beta-lactamase_T126K|0.8629906270000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIKMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2919|beta-lactamase_L38H|0.86287628 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQHGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2920|beta-lactamase_F14G|0.862785389 -MSIQHFRVALIPFGAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2921|beta-lactamase_S240T|0.8627023159999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGTRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2922|beta-lactamase_F17K|0.86267886 -MSIQHFRVALIPFFAAKCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2923|beta-lactamase_R176E|0.86251467 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEEDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2924|beta-lactamase_F228R|0.8624345290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWRIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2925|beta-lactamase_K30N|0.862384685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVNVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2926|beta-lactamase_A23P|0.862255678 -MSIQHFRVALIPFFAAFCLPVFPHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2927|beta-lactamase_T158F|0.8620289390000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVFRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2928|beta-lactamase_H285D|0.861871589 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKDW ->2929|beta-lactamase_Q203W|0.861790471 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRWQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2930|beta-lactamase_F228S|0.861758219 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWSIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2931|beta-lactamase_G279T|0.861276398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEITASLIKHW ->2932|beta-lactamase_L89A|0.86112198 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQAGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2933|beta-lactamase_S201K|0.8607046620000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAKRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2934|beta-lactamase_Q204F|0.8607046620000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQFLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2935|beta-lactamase_G141K|0.8607046620000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIKGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2936|beta-lactamase_V106R|0.860608884 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPRTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2937|beta-lactamase_G236S|0.860560995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2938|beta-lactamase_F22I|0.8604994229999999 -MSIQHFRVALIPFFAAFCLPVIAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2939|beta-lactamase_A123V|0.8603010259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSVAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2940|beta-lactamase_S240Q|0.8602873440000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGQRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2941|beta-lactamase_L89I|0.8602560690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQIGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2942|beta-lactamase_M1L|0.860232613 -LSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2943|beta-lactamase_A34G|0.8601720190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDGEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2944|beta-lactamase_G216E|0.860127062 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAEPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2945|beta-lactamase_L10W|0.860065491 -MSIQHFRVAWIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2946|beta-lactamase_N168D|0.859957985 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELDEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2947|beta-lactamase_E87A|0.859849502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQAQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2948|beta-lactamase_W227Y|0.8598358190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGYFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2949|beta-lactamase_R41E|0.859717563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAEVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2950|beta-lactamase_W286Y|0.859717563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHY ->2951|beta-lactamase_G52E|0.85964524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSEKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2952|beta-lactamase_A276I|0.8595142790000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIIEIGASLIKHW ->2953|beta-lactamase_L167N|0.8593471559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPENNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2954|beta-lactamase_R202I|0.8593471559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASIQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2955|beta-lactamase_D113F|0.8593471559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTFGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2956|beta-lactamase_E62G|0.8589532940000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEGRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2957|beta-lactamase_R238D|0.8589190870000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEDGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2958|beta-lactamase_P165S|0.858704075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWESELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2959|beta-lactamase_S240N|0.8586962570000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGNRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2960|beta-lactamase_S96P|0.8582633009999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYPQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2961|beta-lactamase_F14W|0.858236914 -MSIQHFRVALIPFWAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2962|beta-lactamase_V21I|0.858236914 -MSIQHFRVALIPFFAAFCLPIFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2963|beta-lactamase_R63Y|0.858198798 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEYFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2964|beta-lactamase_S264C|0.8579271009999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGCQATMDERNRQIAEIGASLIKHW ->2965|beta-lactamase_R63A|0.857780502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEAFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2966|beta-lactamase_F6A|0.857780502 -MSIQHARVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2967|beta-lactamase_I11S|0.857746296 -MSIQHFRVALSPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2968|beta-lactamase_I244A|0.85763879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIAAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2969|beta-lactamase_M66A|0.857601652 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPAMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2970|beta-lactamase_E46I|0.857601652 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIILDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2971|beta-lactamase_L38P|0.857601652 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQPGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2972|beta-lactamase_K30H|0.857601652 -MSIQHFRVALIPFFAAFCLPVFAHPETLVHVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2973|beta-lactamase_A148P|0.857490237 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTPFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2974|beta-lactamase_A183D|0.857303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPADMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2975|beta-lactamase_V72C|0.857261542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKCLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2976|beta-lactamase_E87C|0.857261542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQCQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2977|beta-lactamase_F149C|0.857106147 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTACLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2978|beta-lactamase_P181A|0.857097351 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMAAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2979|beta-lactamase_I3V|0.856881362 -MSVQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2980|beta-lactamase_P249H|0.856871589 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGHDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2981|beta-lactamase_A124G|0.856833473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAGITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2982|beta-lactamase_P12D|0.856756265 -MSIQHFRVALIDFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2983|beta-lactamase_D48C|0.8567181490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELCLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2984|beta-lactamase_P105V|0.856703489 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSVVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2985|beta-lactamase_G52A|0.85620603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSAKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2986|beta-lactamase_F149E|0.856190393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAELHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2987|beta-lactamase_T69H|0.8559832 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSHFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2988|beta-lactamase_G226Y|0.85580044 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAYWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2989|beta-lactamase_V214Q|0.855715412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKQAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2990|beta-lactamase_A185C|0.855653841 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMCTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2991|beta-lactamase_L73H|0.855517993 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVHLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2992|beta-lactamase_P249C|0.855517993 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGCDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2993|beta-lactamase_R81T|0.855517993 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSTVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2994|beta-lactamase_T116C|0.8552746379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMCVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2995|beta-lactamase_V106K|0.8552746379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPKTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2996|beta-lactamase_L38C|0.8551612690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQCGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2997|beta-lactamase_P224G|0.855071355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALGAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2998|beta-lactamase_A170Q|0.8550459440000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEQIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->2999|beta-lactamase_D113P|0.854928665 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTPGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3000|beta-lactamase_K30E|0.8548778440000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVEVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3001|beta-lactamase_M1I|0.854809431 -ISIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3002|beta-lactamase_L136M|0.854713653 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLMLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3003|beta-lactamase_S254P|0.854478118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPPRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3004|beta-lactamase_T198P|0.854272879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLPLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3005|beta-lactamase_A230M|0.8540598220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIMDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3006|beta-lactamase_D99W|0.85404614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNWLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3007|beta-lactamase_P224K|0.853929838 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALKAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3008|beta-lactamase_V117T|0.8536688920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTTRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3009|beta-lactamase_R271H|0.853646413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEHNRQIAEIGASLIKHW ->3010|beta-lactamase_T198Y|0.8535604090000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLYLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3011|beta-lactamase_R81E|0.853521315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSEVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3012|beta-lactamase_N98C|0.8534656079999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQCDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3013|beta-lactamase_M115C|0.853401104 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGCTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3014|beta-lactamase_T126R|0.8533874220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIRMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3015|beta-lactamase_F64M|0.8533805809999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERMPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3016|beta-lactamase_P105I|0.853028743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSIVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3017|beta-lactamase_S201S|0.852993515 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3018|beta-lactamase_G216V|0.8529056 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAVPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3019|beta-lactamase_I244T|0.852848915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGITAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3020|beta-lactamase_Y44V|0.85283621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGVIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3021|beta-lactamase_F149S|0.8526739740000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTASLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3022|beta-lactamase_R162K|0.8525606040000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDKWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3023|beta-lactamase_E108P|0.852466781 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTPKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3024|beta-lactamase_I283W|0.852442348 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLWKHW ->3025|beta-lactamase_N168T|0.852164787 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELTEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3026|beta-lactamase_L247C|0.8520172109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAACGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3027|beta-lactamase_T262L|0.8520172109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTLGSQATMDERNRQIAEIGASLIKHW ->3028|beta-lactamase_L100T|0.8520172109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDTVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3029|beta-lactamase_G141D|0.8520172109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIDGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3030|beta-lactamase_T178C|0.851871589 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDCTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3031|beta-lactamase_K144K|0.851840116 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3032|beta-lactamase_V82R|0.851832496 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRRDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3033|beta-lactamase_F13G|0.851163028 -MSIQHFRVALIPGFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3034|beta-lactamase_G226M|0.851158141 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAMWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3035|beta-lactamase_L191Y|0.851108297 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKYLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3036|beta-lactamase_R91A|0.850941175 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGARIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3037|beta-lactamase_G263Q|0.850620612 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTQSQATMDERNRQIAEIGASLIKHW ->3038|beta-lactamase_N168Q|0.850551222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELQEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3039|beta-lactamase_T126N|0.8505394940000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAINMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3040|beta-lactamase_H5G|0.850514083 -MSIQGFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3041|beta-lactamase_T116A|0.850483786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMAVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3042|beta-lactamase_R41W|0.850483786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAWVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3043|beta-lactamase_V106T|0.850431988 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPTTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3044|beta-lactamase_S2G|0.8504173279999999 -MGIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3045|beta-lactamase_V82F|0.850368462 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRFDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3046|beta-lactamase_M184A|0.850317641 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAAATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3047|beta-lactamase_R63C|0.850317641 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEECFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3048|beta-lactamase_I3W|0.850317641 -MSWQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3049|beta-lactamase_P143V|0.8501847240000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGVKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3050|beta-lactamase_A15P|0.850062559 -MSIQHFRVALIPFFPAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3051|beta-lactamase_G141Q|0.849845592 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIQGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3052|beta-lactamase_F149R|0.849547508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTARLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3053|beta-lactamase_L160Q|0.8493637709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRQDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3054|beta-lactamase_S2D|0.849352043 -MDIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3055|beta-lactamase_P165M|0.849009978 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEMELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3056|beta-lactamase_V214R|0.849009978 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKRAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3057|beta-lactamase_T198F|0.849009978 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLFLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3058|beta-lactamase_F70G|0.8489405879999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTGKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3059|beta-lactamase_L223K|0.848849697 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAKPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3060|beta-lactamase_F70S|0.848224208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTSKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3061|beta-lactamase_R176T|0.8482085709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDETDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3062|beta-lactamase_G263R|0.84820173 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTRSQATMDERNRQIAEIGASLIKHW ->3063|beta-lactamase_G263H|0.8481929340000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTHSQATMDERNRQIAEIGASLIKHW ->3064|beta-lactamase_F58K|0.848107907 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESKRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3065|beta-lactamase_T147L|0.848082496 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELLAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3066|beta-lactamase_G52S|0.848064904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSSKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3067|beta-lactamase_R159V|0.848049267 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTVLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3068|beta-lactamase_P143T|0.847939806 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGTKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3069|beta-lactamase_A183L|0.847823505 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPALMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3070|beta-lactamase_V106N|0.8477267490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPNTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3071|beta-lactamase_D161H|0.847518579 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLHRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3072|beta-lactamase_A230I|0.847372957 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIIDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3073|beta-lactamase_L55W|0.8471305809999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIWESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3074|beta-lactamase_E102C|0.8471305809999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVCYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3075|beta-lactamase_D212G|0.847074873 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAGKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3076|beta-lactamase_I125T|0.8467660379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAATTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3077|beta-lactamase_R91Q|0.8467660379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGQRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3078|beta-lactamase_E35A|0.8463428559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAADQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3079|beta-lactamase_I140T|0.846164005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTTGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3080|beta-lactamase_Y260V|0.8461532540000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIVTTGSQATMDERNRQIAEIGASLIKHW ->3081|beta-lactamase_L73G|0.845282457 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVGLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3082|beta-lactamase_G226P|0.845267797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAPWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3083|beta-lactamase_G154R|0.845140745 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMRDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3084|beta-lactamase_M268R|0.8450234659999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATRDERNRQIAEIGASLIKHW ->3085|beta-lactamase_L223S|0.8449814409999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSASPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3086|beta-lactamase_E46C|0.844909118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYICLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3087|beta-lactamase_L247W|0.844415569 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAWGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3088|beta-lactamase_W208F|0.8441986020000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDFMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3089|beta-lactamase_D212S|0.8439982509999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEASKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3090|beta-lactamase_P143A|0.843873153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGAKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3091|beta-lactamase_I283Q|0.8437539190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLQKHW ->3092|beta-lactamase_R202M|0.8436405490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASMQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3093|beta-lactamase_G263M|0.8436405490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTMSQATMDERNRQIAEIGASLIKHW ->3094|beta-lactamase_D174S|0.84351252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNSERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3095|beta-lactamase_P165R|0.843507633 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWERELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3096|beta-lactamase_I140A|0.84332976 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTAGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3097|beta-lactamase_V258T|0.843273075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVTIYTTGSQATMDERNRQIAEIGASLIKHW ->3098|beta-lactamase_G142T|0.842605561 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGTPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3099|beta-lactamase_R162A|0.842575264 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDAWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3100|beta-lactamase_M115V|0.8425693999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGVTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3101|beta-lactamase_V42Y|0.8423104090000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARYGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3102|beta-lactamase_L38N|0.8417474690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQNGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3103|beta-lactamase_P165D|0.841700557 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEDELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3104|beta-lactamase_R176G|0.841383903 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEGDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3105|beta-lactamase_C18C|0.8411685790000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3106|beta-lactamase_L55G|0.840931401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIGESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3107|beta-lactamase_L100C|0.8409030590000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDCVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3108|beta-lactamase_R63N|0.8409030590000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEENFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3109|beta-lactamase_L135T|0.840728118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANTLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3110|beta-lactamase_E62R|0.840656773 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPERRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3111|beta-lactamase_F228H|0.840575655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWHIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3112|beta-lactamase_P249V|0.8405267890000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGVDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3113|beta-lactamase_L74A|0.840037148 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLACGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3114|beta-lactamase_V72S|0.839800635 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKSLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3115|beta-lactamase_A123G|0.839142895 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSGAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3116|beta-lactamase_M66T|0.839097938 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPTMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3117|beta-lactamase_A34Y|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDYEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3118|beta-lactamase_T27M|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPEMLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3119|beta-lactamase_A77W|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGWVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3120|beta-lactamase_R271D|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEDNRQIAEIGASLIKHW ->3121|beta-lactamase_T139F|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTFIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3122|beta-lactamase_Q204W|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQWLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3123|beta-lactamase_G263E|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTESQATMDERNRQIAEIGASLIKHW ->3124|beta-lactamase_R63F|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEFFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3125|beta-lactamase_E62K|0.838986523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEKRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3126|beta-lactamase_A23C|0.838986523 -MSIQHFRVALIPFFAAFCLPVFCHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3127|beta-lactamase_D161T|0.838469517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLTRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3128|beta-lactamase_D99C|0.8384607209999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNCLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3129|beta-lactamase_D161V|0.838455835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLVRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3130|beta-lactamase_L38Q|0.838129408 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQQGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3131|beta-lactamase_I93Y|0.838111816 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRYHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3132|beta-lactamase_L74T|0.838105952 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLTCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3133|beta-lactamase_R162C|0.8380424259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3134|beta-lactamase_V82K|0.837986718 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRKDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3135|beta-lactamase_R81G|0.837753137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSGVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3136|beta-lactamase_T139W|0.837656382 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTWIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3137|beta-lactamase_G216I|0.837176515 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAIPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3138|beta-lactamase_R81I|0.837176515 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSIVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3139|beta-lactamase_P105L|0.837142308 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSLVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3140|beta-lactamase_E62I|0.8370699859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEIRFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3141|beta-lactamase_L38W|0.8369996190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQWGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3142|beta-lactamase_M268K|0.8368588840000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATKDERNRQIAEIGASLIKHW ->3143|beta-lactamase_S201R|0.836554935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLARRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3144|beta-lactamase_L47F|0.836024247 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEFDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3145|beta-lactamase_P253E|0.836024247 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKESRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3146|beta-lactamase_P143S|0.8359323790000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGSKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3147|beta-lactamase_A215T|0.835821941 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3148|beta-lactamase_I256C|0.835792621 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRCVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3149|beta-lactamase_F64Y|0.8355570859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERYPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3150|beta-lactamase_I243M|0.835295162 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGMIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3151|beta-lactamase_I45S|0.835107516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYSELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3152|beta-lactamase_R81V|0.835041057 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSVVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3153|beta-lactamase_P249I|0.835035194 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGIDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3154|beta-lactamase_T116M|0.834914005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMMVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3155|beta-lactamase_L111N|0.834914005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHNTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3156|beta-lactamase_P217I|0.834914005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGILLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3157|beta-lactamase_F6E|0.834914005 -MSIQHERVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3158|beta-lactamase_L160H|0.834713653 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRHDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3159|beta-lactamase_I283S|0.8343686570000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLSKHW ->3160|beta-lactamase_F228L|0.8343188140000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3161|beta-lactamase_L111G|0.83419567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHGTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3162|beta-lactamase_A266W|0.834134099 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQWTMDERNRQIAEIGASLIKHW ->3163|beta-lactamase_A170E|0.833879017 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEEIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3164|beta-lactamase_T187F|0.8338672890000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATFLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3165|beta-lactamase_K213W|0.8335564990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADWVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3166|beta-lactamase_V214H|0.833387422 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKHAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3167|beta-lactamase_D161C|0.833276984 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLCRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3168|beta-lactamase_L218L|0.83312246 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3169|beta-lactamase_A266I|0.833111816 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQITMDERNRQIAEIGASLIKHW ->3170|beta-lactamase_L89V|0.832649541 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQVGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3171|beta-lactamase_L150S|0.832575264 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFSHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3172|beta-lactamase_G154H|0.83247069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMHDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3173|beta-lactamase_R59R|0.832036929 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3174|beta-lactamase_G226F|0.832023075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAFWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3175|beta-lactamase_Y103G|0.83187843 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEGSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3176|beta-lactamase_D99G|0.831725968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNGLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3177|beta-lactamase_G52K|0.831673192 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSKKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3178|beta-lactamase_M184C|0.831582301 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAACATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3179|beta-lactamase_T116R|0.831582301 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMRVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3180|beta-lactamase_E195A|0.831582301 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGALLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3181|beta-lactamase_L135A|0.831460135 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANALLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3182|beta-lactamase_M209C|0.831321355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWCEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3183|beta-lactamase_I140F|0.831321355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTFGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3184|beta-lactamase_S51V|0.831321355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNVGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3185|beta-lactamase_D161A|0.8310594309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLARWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3186|beta-lactamase_Y103N|0.830841487 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVENSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3187|beta-lactamase_L135F|0.830824873 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANFLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3188|beta-lactamase_P224T|0.830813145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALTAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3189|beta-lactamase_A230S|0.830812168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFISDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3190|beta-lactamase_A182P|0.83050431 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPPAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3191|beta-lactamase_L73Y|0.83035087 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVYLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3192|beta-lactamase_P165Q|0.8302883209999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEQELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3193|beta-lactamase_P12P|0.8302196359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3194|beta-lactamase_L146A|0.829867093 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEATAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3195|beta-lactamase_L38E|0.82967847 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQEGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3196|beta-lactamase_P143Q|0.829442934 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGQKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3197|beta-lactamase_R255V|0.829348133 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSVIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3198|beta-lactamase_L10H|0.829151691 -MSIQHFRVAHIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3199|beta-lactamase_A222W|0.82907155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSWLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3200|beta-lactamase_G85F|0.82907155 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAFQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3201|beta-lactamase_L247T|0.828805717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAATGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3202|beta-lactamase_T198I|0.828621003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLILASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3203|beta-lactamase_P224D|0.828437265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALDAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3204|beta-lactamase_G242C|0.828279916 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRCIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3205|beta-lactamase_L28E|0.828127453 -MSIQHFRVALIPFFAAFCLPVFAHPETEVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3206|beta-lactamase_I54N|0.828127453 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKNLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3207|beta-lactamase_T116V|0.82796033 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMVVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3208|beta-lactamase_F22V|0.8278958270000001 -MSIQHFRVALIPFFAAFCLPVVAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3209|beta-lactamase_V82Q|0.827709158 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRQDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3210|beta-lactamase_E166P|0.827650518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPPLNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3211|beta-lactamase_G142N|0.82758406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGNPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3212|beta-lactamase_L192A|0.82742671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLATGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3213|beta-lactamase_C75M|0.8267699470000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLMGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3214|beta-lactamase_G43S|0.826722058 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVSYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3215|beta-lactamase_A185V|0.826598915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMVTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3216|beta-lactamase_G141E|0.8264562259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3217|beta-lactamase_M268E|0.8264562259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATEDERNRQIAEIGASLIKHW ->3218|beta-lactamase_G76C|0.826160096 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCCAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3219|beta-lactamase_M115A|0.8260780000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGATVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3220|beta-lactamase_A235T|0.8260780000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGTGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3221|beta-lactamase_Y103A|0.82606725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEASPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3222|beta-lactamase_F6P|0.825954857 -MSIQHPRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3223|beta-lactamase_T69S|0.8256411359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSSFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3224|beta-lactamase_M127G|0.825308845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITGSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3225|beta-lactamase_I125I|0.825051378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3226|beta-lactamase_N130N|0.824939447 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3227|beta-lactamase_N168V|0.8248407059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELVEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3228|beta-lactamase_T116K|0.824017797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMKVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3229|beta-lactamase_A211I|0.824017797 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEIDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3230|beta-lactamase_V31T|0.823919087 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKTKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3231|beta-lactamase_G236N|0.823526202 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGANERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3232|beta-lactamase_P165E|0.8232232309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEEELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3233|beta-lactamase_R92D|0.823076632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRDIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3234|beta-lactamase_L135C|0.82294567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANCLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3235|beta-lactamase_T261Y|0.82269743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYYTGSQATMDERNRQIAEIGASLIKHW ->3236|beta-lactamase_G142S|0.82269743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGSPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3237|beta-lactamase_R159D|0.82269743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTDLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3238|beta-lactamase_R59Q|0.82269743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFQPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3239|beta-lactamase_A16K|0.82269743 -MSIQHFRVALIPFFAKFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3240|beta-lactamase_C18F|0.82269743 -MSIQHFRVALIPFFAAFFLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3241|beta-lactamase_D174C|0.8223602520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNCERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3242|beta-lactamase_L89W|0.821896022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQWGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3243|beta-lactamase_P12E|0.821635076 -MSIQHFRVALIEFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3244|beta-lactamase_I93C|0.821574482 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRCHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3245|beta-lactamase_T27A|0.821560799 -MSIQHFRVALIPFFAAFCLPVFAHPEALVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3246|beta-lactamase_A246G|0.821513888 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAGLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3247|beta-lactamase_L197F|0.821050635 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELFTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3248|beta-lactamase_P165G|0.8204652170000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3249|beta-lactamase_P65A|0.8204114640000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFAMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3250|beta-lactamase_R7C|0.8203704159999999 -MSIQHFCVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3251|beta-lactamase_L55S|0.8201006740000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKISESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3252|beta-lactamase_P224E|0.8200918779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALEAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3253|beta-lactamase_G141A|0.8197654520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIAGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3254|beta-lactamase_T138P|0.8196159209999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLPTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3255|beta-lactamase_F13H|0.819327609 -MSIQHFRVALIPHFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3256|beta-lactamase_L10Q|0.818788125 -MSIQHFRVAQIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3257|beta-lactamase_I93F|0.818427492 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRFHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3258|beta-lactamase_L38D|0.818410878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQDGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3259|beta-lactamase_G154C|0.818385467 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMCDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3260|beta-lactamase_V257T|0.818127453 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRITVIYTTGSQATMDERNRQIAEIGASLIKHW ->3261|beta-lactamase_R92G|0.817940784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRGIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3262|beta-lactamase_D83S|0.8178968040000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVSAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3263|beta-lactamase_T261E|0.8178107990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYETGSQATMDERNRQIAEIGASLIKHW ->3264|beta-lactamase_P25P|0.8176920529999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3265|beta-lactamase_N272E|0.8172674059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERERQIAEIGASLIKHW ->3266|beta-lactamase_L167S|0.817089533 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPESNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3267|beta-lactamase_L137A|0.8170250290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLATTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3268|beta-lactamase_F22T|0.816948798 -MSIQHFRVALIPFFAAFCLPVTAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3269|beta-lactamase_V42T|0.816642895 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARTGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3270|beta-lactamase_P143C|0.816323309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGCKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3271|beta-lactamase_R176D|0.816280307 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEDDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3272|beta-lactamase_L120I|0.816243168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREICSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3273|beta-lactamase_R159A|0.816181597 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTALDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3274|beta-lactamase_V106G|0.815872762 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPGTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3275|beta-lactamase_S264Q|0.81571639 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGQQATMDERNRQIAEIGASLIKHW ->3276|beta-lactamase_F6G|0.81571639 -MSIQHGRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3277|beta-lactamase_G85V|0.8154661940000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAVQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3278|beta-lactamase_C18Y|0.8151798379999999 -MSIQHFRVALIPFFAAFYLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3279|beta-lactamase_H24P|0.814271902 -MSIQHFRVALIPFFAAFCLPVFAPPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3280|beta-lactamase_S104G|0.814112598 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYGPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3281|beta-lactamase_E277W|0.814074482 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAWIGASLIKHW ->3282|beta-lactamase_A246E|0.8139659990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAELGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3283|beta-lactamase_D174Q|0.813568227 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNQERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3284|beta-lactamase_T27Q|0.813534998 -MSIQHFRVALIPFFAAFCLPVFAHPEQLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3285|beta-lactamase_G141S|0.813534998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTISGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3286|beta-lactamase_L55A|0.81332585 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIAESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3287|beta-lactamase_L150W|0.8133092359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFWHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3288|beta-lactamase_G234C|0.813267211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSCAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3289|beta-lactamase_D174N|0.8132007529999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNNERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3290|beta-lactamase_L188S|0.8131645909999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTSRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3291|beta-lactamase_I3E|0.813162637 -MSEQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3292|beta-lactamase_L191A|0.8131528640000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKALTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3293|beta-lactamase_L146Y|0.8130013779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEYTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3294|beta-lactamase_I140C|0.8129241690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTCGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3295|beta-lactamase_I140Q|0.8129241690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTQGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3296|beta-lactamase_R159I|0.8129241690000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTILDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3297|beta-lactamase_V42A|0.8128665070000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARAGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3298|beta-lactamase_N168C|0.8128147090000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELCEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3299|beta-lactamase_P224S|0.812795162 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALSAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3300|beta-lactamase_A170K|0.8127717059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEKIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3301|beta-lactamase_D212T|0.81238664 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEATKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3302|beta-lactamase_D231A|0.8122771790000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAAKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3303|beta-lactamase_F70I|0.812265452 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTIKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3304|beta-lactamase_V78A|0.8121315579999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAALSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3305|beta-lactamase_L197K|0.811993755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELKTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3306|beta-lactamase_P224H|0.811895045 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALHAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3307|beta-lactamase_R202N|0.811421042 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASNQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3308|beta-lactamase_L120C|0.81126076 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRECCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3309|beta-lactamase_I11I|0.811223378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3310|beta-lactamase_M66Q|0.811156186 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPQMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3311|beta-lactamase_V21K|0.8109333559999999 -MSIQHFRVALIPFFAAFCLPKFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3312|beta-lactamase_L137C|0.8105140829999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLCTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3313|beta-lactamase_G263L|0.810480854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTLSQATMDERNRQIAEIGASLIKHW ->3314|beta-lactamase_S201L|0.8103743259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLALRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3315|beta-lactamase_K232R|0.810155405 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADRSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3316|beta-lactamase_R7R|0.810050708 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3317|beta-lactamase_T131L|0.809916937 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNLAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3318|beta-lactamase_T261H|0.809837774 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYHTGSQATMDERNRQIAEIGASLIKHW ->3319|beta-lactamase_R91Y|0.8095416440000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGYRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3320|beta-lactamase_E195W|0.809370612 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGWLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3321|beta-lactamase_L282Q|0.809328587 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASQIKHW ->3322|beta-lactamase_P143G|0.809301222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGGKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3323|beta-lactamase_A15N|0.809123348 -MSIQHFRVALIPFFNAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3324|beta-lactamase_V214C|0.809060799 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKCAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3325|beta-lactamase_V82N|0.808803763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRNDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3326|beta-lactamase_F6T|0.8086014559999999 -MSIQHTRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3327|beta-lactamase_S104T|0.808580932 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYTPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3328|beta-lactamase_L205V|0.8085701820000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQVIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3329|beta-lactamase_E119M|0.808324873 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRMLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3330|beta-lactamase_R91M|0.808324873 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGMRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3331|beta-lactamase_V82M|0.8081694779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRMDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3332|beta-lactamase_G52M|0.80742671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSMKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3333|beta-lactamase_L38K|0.807124717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQKGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3334|beta-lactamase_V21N|0.807080737 -MSIQHFRVALIPFFAAFCLPNFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3335|beta-lactamase_R241K|0.806978118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSKGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3336|beta-lactamase_P224Q|0.806659509 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALQAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3337|beta-lactamase_L79V|0.806408337 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVVSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3338|beta-lactamase_P105M|0.806408337 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSMVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3339|beta-lactamase_G39G|0.806118517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3340|beta-lactamase_S240H|0.806013497 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGHRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3341|beta-lactamase_R81W|0.8059431290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSWVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3342|beta-lactamase_T27P|0.8058874220000001 -MSIQHFRVALIPFFAAFCLPVFAHPEPLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3343|beta-lactamase_F149N|0.80561768 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTANLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3344|beta-lactamase_E119K|0.805471081 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRKLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3345|beta-lactamase_L191T|0.804631558 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKTLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3346|beta-lactamase_I283R|0.804224013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLRKHW ->3347|beta-lactamase_G85W|0.804081323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAWQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3348|beta-lactamase_P249L|0.803268188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGLDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3349|beta-lactamase_R159E|0.803038516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTELDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3350|beta-lactamase_P105Q|0.802918305 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSQVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3351|beta-lactamase_D48G|0.802649541 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELGLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3352|beta-lactamase_W208L|0.802368071 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDLMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3353|beta-lactamase_L89E|0.8021814009999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQEGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3354|beta-lactamase_A40V|0.8021540359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGVRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3355|beta-lactamase_L282S|0.8021511040000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASSIKHW ->3356|beta-lactamase_F228Q|0.80175431 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWQIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3357|beta-lactamase_P105T|0.801652668 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSTVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3358|beta-lactamase_A230V|0.801642895 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIVDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3359|beta-lactamase_P224R|0.801243168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALRAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3360|beta-lactamase_L47E|0.8011962570000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEEDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3361|beta-lactamase_G141M|0.80097929 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIMGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3362|beta-lactamase_I243Y|0.8009040359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGYIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3363|beta-lactamase_A40W|0.8004857409999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGWRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3364|beta-lactamase_L89S|0.799825068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQSGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3365|beta-lactamase_V214G|0.799771315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKGAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3366|beta-lactamase_R176V|0.799637422 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEVDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3367|beta-lactamase_I54D|0.7991067340000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKDLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3368|beta-lactamase_P25A|0.799005092 -MSIQHFRVALIPFFAAFCLPVFAHAETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3369|beta-lactamase_L136A|0.7985936379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLALTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3370|beta-lactamase_V101W|0.7982642790000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLWEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3371|beta-lactamase_E119T|0.796978118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRTLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3372|beta-lactamase_L89G|0.796939025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQGGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3373|beta-lactamase_T126H|0.796291057 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIHMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3374|beta-lactamase_R159W|0.796086796 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTWLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3375|beta-lactamase_D48M|0.796042817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELMLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3376|beta-lactamase_F228N|0.7953997359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWNIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3377|beta-lactamase_G263K|0.795284412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTKSQATMDERNRQIAEIGASLIKHW ->3378|beta-lactamase_M66G|0.7950889459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPGMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3379|beta-lactamase_P105E|0.794505483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSEVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3380|beta-lactamase_G52H|0.794406773 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSHKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3381|beta-lactamase_R159C|0.7938975859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTCLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3382|beta-lactamase_L135E|0.7938135359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANELLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3383|beta-lactamase_D155N|0.793641527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGNHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3384|beta-lactamase_P105K|0.7933776490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSKVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3385|beta-lactamase_N168M|0.7931206120000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELMEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3386|beta-lactamase_V257A|0.792952512 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIAVIYTTGSQATMDERNRQIAEIGASLIKHW ->3387|beta-lactamase_L10N|0.792952512 -MSIQHFRVANIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3388|beta-lactamase_P224N|0.7928283909999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALNAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3389|beta-lactamase_R91E|0.792779525 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGERIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3390|beta-lactamase_S201Q|0.7927472729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAQRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3391|beta-lactamase_G52Q|0.7927472729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSQKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3392|beta-lactamase_T116I|0.792626085 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMIVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3393|beta-lactamase_L137S|0.792467758 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLSTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3394|beta-lactamase_M268D|0.7924472340000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATDDERNRQIAEIGASLIKHW ->3395|beta-lactamase_R241S|0.791879408 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3396|beta-lactamase_C75F|0.79160087 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLFGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3397|beta-lactamase_F149D|0.791552004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTADLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3398|beta-lactamase_L89T|0.79154223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQTGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3399|beta-lactamase_R63E|0.791422996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEEFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3400|beta-lactamase_G226W|0.7913350370000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAWWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3401|beta-lactamase_R220K|0.79119137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLKSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3402|beta-lactamase_P105H|0.7908854670000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSHVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3403|beta-lactamase_R41C|0.790877649 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGACVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3404|beta-lactamase_L38R|0.790189611 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQRGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3405|beta-lactamase_Y103M|0.7901202209999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEMSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3406|beta-lactamase_A9E|0.7901202209999999 -MSIQHFRVELIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3407|beta-lactamase_C18L|0.7901202209999999 -MSIQHFRVALIPFFAAFLLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3408|beta-lactamase_E87S|0.7896139659999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQSQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3409|beta-lactamase_A246W|0.789572918 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAWLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3410|beta-lactamase_G141R|0.789516233 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIRGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3411|beta-lactamase_L47S|0.789226945 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIESDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3412|beta-lactamase_W208Y|0.7889640440000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDYMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3413|beta-lactamase_G154M|0.788867289 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMMDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3414|beta-lactamase_R159Y|0.788867289 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTYLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3415|beta-lactamase_V21F|0.788751964 -MSIQHFRVALIPFFAAFCLPFFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3416|beta-lactamase_R59A|0.788620025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFAPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3417|beta-lactamase_R159L|0.7882613470000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTLLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3418|beta-lactamase_L120A|0.788203685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREACSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3419|beta-lactamase_L197V|0.788151886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELVTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3420|beta-lactamase_S104H|0.788047312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYHPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3421|beta-lactamase_R91F|0.787793208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGFRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3422|beta-lactamase_D161Q|0.787703294 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLQRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3423|beta-lactamase_P165H|0.787385663 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEHELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3424|beta-lactamase_A235L|0.7873240909999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGLGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3425|beta-lactamase_S264M|0.7871579459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGMQATMDERNRQIAEIGASLIKHW ->3426|beta-lactamase_R162M|0.7871579459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDMWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3427|beta-lactamase_P105A|0.7867015340000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSAVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3428|beta-lactamase_A23N|0.7860477029999999 -MSIQHFRVALIPFFAAFCLPVFNHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3429|beta-lactamase_H5F|0.7860477029999999 -MSIQFFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3430|beta-lactamase_H110T|0.785717367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKTLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3431|beta-lactamase_F70T|0.785677297 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTTKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3432|beta-lactamase_V21R|0.785669478 -MSIQHFRVALIPFFAAFCLPRFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3433|beta-lactamase_V82L|0.7856518859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRLDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3434|beta-lactamase_R176I|0.7855121290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEIDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3435|beta-lactamase_G142D|0.785500401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGDPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3436|beta-lactamase_T27H|0.785108493 -MSIQHFRVALIPFFAAFCLPVFAHPEHLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3437|beta-lactamase_L146W|0.784937461 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEWTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3438|beta-lactamase_R91D|0.784914005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGDRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3439|beta-lactamase_I3G|0.7843021990000001 -MSGQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3440|beta-lactamase_T131M|0.784118462 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNMAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3441|beta-lactamase_R255M|0.784118462 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSMIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3442|beta-lactamase_Y103S|0.7839063820000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVESSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3443|beta-lactamase_P217W|0.783604388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGWLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3444|beta-lactamase_C121L|0.7833053259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELLSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3445|beta-lactamase_E56Y|0.7832515729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILYSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3446|beta-lactamase_N130S|0.783235936 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDSTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3447|beta-lactamase_I256F|0.7831391809999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRFVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3448|beta-lactamase_A16E|0.782329955 -MSIQHFRVALIPFFAEFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3449|beta-lactamase_N130Y|0.7819751859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDYTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3450|beta-lactamase_R255I|0.781407359 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSIIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3451|beta-lactamase_G114Y|0.78134872 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDYMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3452|beta-lactamase_G142E|0.781088751 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGEPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3453|beta-lactamase_G194I|0.780982222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTIELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3454|beta-lactamase_P105R|0.78088449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSRVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3455|beta-lactamase_R271E|0.780812168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEENRQIAEIGASLIKHW ->3456|beta-lactamase_R255H|0.7806812059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSHIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3457|beta-lactamase_A276D|0.780678274 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIDEIGASLIKHW ->3458|beta-lactamase_S51L|0.7805717459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNLGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3459|beta-lactamase_L89C|0.780440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQCGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3460|beta-lactamase_A133C|0.7803469609999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTACNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3461|beta-lactamase_M66H|0.7800694 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPHMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3462|beta-lactamase_E87Y|0.7794693220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQYQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3463|beta-lactamase_R41G|0.779311972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAGVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3464|beta-lactamase_V78C|0.779186875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGACLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3465|beta-lactamase_R81C|0.7788115809999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSCVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3466|beta-lactamase_A246Q|0.778800831 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAQLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3467|beta-lactamase_T267W|0.778800831 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQAWMDERNRQIAEIGASLIKHW ->3468|beta-lactamase_N272G|0.778717758 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERGRQIAEIGASLIKHW ->3469|beta-lactamase_L74C|0.7784851540000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLCCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3470|beta-lactamase_V214F|0.778314122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKFAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3471|beta-lactamase_K30W|0.778274052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVWVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3472|beta-lactamase_V21D|0.778198798 -MSIQHFRVALIPFFAAFCLPDFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3473|beta-lactamase_N134D|0.7780551309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAADLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3474|beta-lactamase_P105S|0.7772116990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSSVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3475|beta-lactamase_G114S|0.7770621679999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDSMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3476|beta-lactamase_I140S|0.777056304 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTSGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3477|beta-lactamase_V82E|0.777053372 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSREDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3478|beta-lactamase_A23V|0.7769839820000001 -MSIQHFRVALIPFFAAFCLPVFVHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3479|beta-lactamase_W208D|0.776520729 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDDMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3480|beta-lactamase_D231Q|0.77640345 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAQKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3481|beta-lactamase_G52F|0.7763692440000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSFKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3482|beta-lactamase_V82G|0.776095592 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRGDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3483|beta-lactamase_T131V|0.775955835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNVAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3484|beta-lactamase_G114A|0.775545358 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDAMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3485|beta-lactamase_D174G|0.775184724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNGERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3486|beta-lactamase_P12R|0.7748358190000001 -MSIQHFRVALIRFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3487|beta-lactamase_V21E|0.774625694 -MSIQHFRVALIPFFAAFCLPEFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3488|beta-lactamase_G114H|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDHMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3489|beta-lactamase_G114N|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDNMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3490|beta-lactamase_S264K|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGKQATMDERNRQIAEIGASLIKHW ->3491|beta-lactamase_G52T|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSTKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3492|beta-lactamase_K30Y|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVYVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3493|beta-lactamase_G263T|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTTSQATMDERNRQIAEIGASLIKHW ->3494|beta-lactamase_L100Q|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDQVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3495|beta-lactamase_G141C|0.773831128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTICGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3496|beta-lactamase_F13Q|0.773831128 -MSIQHFRVALIPQFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3497|beta-lactamase_P20G|0.773831128 -MSIQHFRVALIPFFAAFCLGVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3498|beta-lactamase_R7M|0.773831128 -MSIQHFMVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3499|beta-lactamase_T187Q|0.772312363 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATQLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3500|beta-lactamase_L218I|0.7722801109999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPILRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3501|beta-lactamase_L146C|0.772241996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKECTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3502|beta-lactamase_N134Q|0.7721462179999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAQLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3503|beta-lactamase_S51C|0.771706421 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNCGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3504|beta-lactamase_F6D|0.771706421 -MSIQHDRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3505|beta-lactamase_F70L|0.7712460999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTLKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3506|beta-lactamase_L136L|0.771187657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3507|beta-lactamase_E46G|0.771179642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIGLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3508|beta-lactamase_C121G|0.77091381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELGSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3509|beta-lactamase_T187H|0.770308845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATHLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3510|beta-lactamase_R162E|0.7697244040000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDEWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3511|beta-lactamase_H5S|0.7691771009999999 -MSIQSFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3512|beta-lactamase_H5W|0.768944498 -MSIQWFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3513|beta-lactamase_T27N|0.7680824959999999 -MSIQHFRVALIPFFAAFCLPVFAHPENLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3514|beta-lactamase_L89H|0.767956421 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQHGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3515|beta-lactamase_D161M|0.76772284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLMRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3516|beta-lactamase_E169P|0.76772284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNPAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3517|beta-lactamase_N272S|0.76752542 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERSRQIAEIGASLIKHW ->3518|beta-lactamase_G141T|0.76709051 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTITGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3519|beta-lactamase_D48T|0.766932183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELTLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3520|beta-lactamase_M115T|0.766771902 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGTTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3521|beta-lactamase_P105Y|0.766313536 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSYVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3522|beta-lactamase_L100W|0.76601252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDWVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3523|beta-lactamase_R255L|0.765940197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSLIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3524|beta-lactamase_E87W|0.7658199859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQWQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3525|beta-lactamase_S104N|0.76568707 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYNPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3526|beta-lactamase_A246N|0.765636249 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIANLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3527|beta-lactamase_D36P|0.7654055999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEPQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3528|beta-lactamase_T158A|0.765217953 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVARLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3529|beta-lactamase_K32D|0.7649462570000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVDDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3530|beta-lactamase_E35S|0.7648553659999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDASDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3531|beta-lactamase_T262G|0.763967953 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTGGSQATMDERNRQIAEIGASLIKHW ->3532|beta-lactamase_I243F|0.76367671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGFIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3533|beta-lactamase_C121I|0.763650323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELISAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3534|beta-lactamase_L150N|0.763233982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFNHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3535|beta-lactamase_L223R|0.76314309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSARPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3536|beta-lactamase_V21Y|0.763091292 -MSIQHFRVALIPFFAAFCLPYFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3537|beta-lactamase_V257M|0.762972058 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIMVIYTTGSQATMDERNRQIAEIGASLIKHW ->3538|beta-lactamase_F70N|0.762748251 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTNKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3539|beta-lactamase_L218C|0.7625088059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPCLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3540|beta-lactamase_L150Q|0.7623690479999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFQHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3541|beta-lactamase_F17R|0.762332887 -MSIQHFRVALIPFFAARCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3542|beta-lactamase_L89Q|0.7620054829999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQQGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3543|beta-lactamase_G76M|0.7616145520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCMAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3544|beta-lactamase_D83G|0.76154614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVGAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3545|beta-lactamase_R81D|0.761301808 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSDVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3546|beta-lactamase_V21H|0.760417328 -MSIQHFRVALIPFFAAFCLPHFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3547|beta-lactamase_A40L|0.75995603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGLRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3548|beta-lactamase_T107M|0.759869048 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVMEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3549|beta-lactamase_Y103T|0.759615921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVETSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3550|beta-lactamase_A245T|0.7594996190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIITALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3551|beta-lactamase_N272A|0.759171237 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERARQIAEIGASLIKHW ->3552|beta-lactamase_I283H|0.7590480940000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLHKHW ->3553|beta-lactamase_Q86Q|0.7589868740000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3554|beta-lactamase_L197H|0.7586747559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELHTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3555|beta-lactamase_L205F|0.758593638 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQFIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3556|beta-lactamase_L197Q|0.758593638 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELQTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3557|beta-lactamase_G52L|0.758461699 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSLKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3558|beta-lactamase_T69C|0.758457789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSCFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3559|beta-lactamase_T131F|0.758400127 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNFAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3560|beta-lactamase_N130C|0.758400127 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDCTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3561|beta-lactamase_G236T|0.757359275 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGATERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3562|beta-lactamase_H110V|0.756584255 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKVLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3563|beta-lactamase_V21Q|0.756511933 -MSIQHFRVALIPFFAAFCLPQFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3564|beta-lactamase_K30G|0.756261738 -MSIQHFRVALIPFFAAFCLPVFAHPETLVGVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3565|beta-lactamase_C18P|0.756061386 -MSIQHFRVALIPFFAAFPLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3566|beta-lactamase_I275C|0.755556108 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQCAEIGASLIKHW ->3567|beta-lactamase_F70Q|0.755506265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTQKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3568|beta-lactamase_L49P|0.755036171 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDPNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3569|beta-lactamase_P249Y|0.754284607 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGYDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3570|beta-lactamase_P181T|0.754144849 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMTAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3571|beta-lactamase_Q88P|0.754011933 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEPLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3572|beta-lactamase_V21M|0.753470495 -MSIQHFRVALIPFFAAFCLPMFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3573|beta-lactamase_T179C|0.753438243 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTCMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3574|beta-lactamase_I11P|0.752981832 -MSIQHFRVALPPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3575|beta-lactamase_D83A|0.7523094309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVAAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3576|beta-lactamase_I45Q|0.752112989 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYQELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3577|beta-lactamase_L135K|0.7519742079999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANKLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3578|beta-lactamase_A123T|0.7518911359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSTAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3579|beta-lactamase_L49G|0.7518911359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDGNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3580|beta-lactamase_Y103V|0.751541253 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEVSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3581|beta-lactamase_T107G|0.74994137 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVGEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3582|beta-lactamase_V214Y|0.749699971 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKYAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3583|beta-lactamase_A23D|0.749397977 -MSIQHFRVALIPFFAAFCLPVFDHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3584|beta-lactamase_P224A|0.749251378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALAAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3585|beta-lactamase_L73Q|0.748715803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVQLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3586|beta-lactamase_I275Y|0.74796033 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQYAEIGASLIKHW ->3587|beta-lactamase_S2E|0.7477687740000001 -MEIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3588|beta-lactamase_G52Y|0.747176515 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSYKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3589|beta-lactamase_P65S|0.747040667 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFSMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3590|beta-lactamase_I283K|0.746614552 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLKKHW ->3591|beta-lactamase_P165F|0.7462109170000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEFELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3592|beta-lactamase_S201Y|0.74609657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAYRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3593|beta-lactamase_M268C|0.745706616 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATCDERNRQIAEIGASLIKHW ->3594|beta-lactamase_T107I|0.745430033 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVIEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3595|beta-lactamase_L150G|0.745384099 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFGHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3596|beta-lactamase_W286F|0.744511347 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHF ->3597|beta-lactamase_E35D|0.744467367 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDADDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3598|beta-lactamase_E56W|0.744454662 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILWSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3599|beta-lactamase_L247F|0.744162441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAFGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3600|beta-lactamase_L223F|0.74360732 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAFPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3601|beta-lactamase_E119R|0.743345397 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRRLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3602|beta-lactamase_L79I|0.7422351540000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVISRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3603|beta-lactamase_V21P|0.7421716279999999 -MSIQHFRVALIPFFAAFCLPPFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3604|beta-lactamase_E56I|0.7420250290000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILISFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3605|beta-lactamase_R91L|0.7416057559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGLRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3606|beta-lactamase_L89D|0.741574482 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQDGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3607|beta-lactamase_G226L|0.741506069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPALWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3608|beta-lactamase_L197R|0.741285194 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELRTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3609|beta-lactamase_A23K|0.741253919 -MSIQHFRVALIPFFAAFCLPVFKHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3610|beta-lactamase_S240D|0.741060409 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGDRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3611|beta-lactamase_G154T|0.740940197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMTDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3612|beta-lactamase_A235V|0.740748642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGVGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3613|beta-lactamase_R271P|0.739551417 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEPNRQIAEIGASLIKHW ->3614|beta-lactamase_I93Q|0.739337383 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRQHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3615|beta-lactamase_T158G|0.739217172 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVGRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3616|beta-lactamase_K252P|0.7385760459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGPPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3617|beta-lactamase_E35G|0.738461699 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAGDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3618|beta-lactamase_F58E|0.7384450840000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESERPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3619|beta-lactamase_P105F|0.738291644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSFVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3620|beta-lactamase_V214W|0.738075655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKWAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3621|beta-lactamase_R202Y|0.737181401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASYQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3622|beta-lactamase_G239N|0.736167914 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERNSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3623|beta-lactamase_L223Q|0.7353078670000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAQPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3624|beta-lactamase_A215P|0.734671628 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVPGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3625|beta-lactamase_F228G|0.734218149 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWGIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3626|beta-lactamase_R241T|0.734022684 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSTGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3627|beta-lactamase_G234M|0.734013888 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSMAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3628|beta-lactamase_P105N|0.734013888 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSNVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3629|beta-lactamase_G52R|0.7337128709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSRKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3630|beta-lactamase_L191W|0.733588751 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKWLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3631|beta-lactamase_L100K|0.7331088840000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDKVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3632|beta-lactamase_L120V|0.7323407059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREVCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3633|beta-lactamase_I11H|0.731672215 -MSIQHFRVALHPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3634|beta-lactamase_F17P|0.731480659 -MSIQHFRVALIPFFAAPCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3635|beta-lactamase_C75L|0.730549267 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLLGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3636|beta-lactamase_G141Y|0.7303948490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIYGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3637|beta-lactamase_P143E|0.730227727 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGEKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3638|beta-lactamase_Q86P|0.7298231140000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGPEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3639|beta-lactamase_D174T|0.729528939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNTERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3640|beta-lactamase_L28P|0.729498642 -MSIQHFRVALIPFFAAFCLPVFAHPETPVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3641|beta-lactamase_D231N|0.72940775 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIANKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3642|beta-lactamase_G279F|0.72940775 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIFASLIKHW ->3643|beta-lactamase_Y103C|0.7291057559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVECSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3644|beta-lactamase_N168I|0.7284900409999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELIEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3645|beta-lactamase_G76V|0.728478313 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCVAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3646|beta-lactamase_A235N|0.728312168 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGNGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3647|beta-lactamase_E87N|0.7282222540000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQNQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3648|beta-lactamase_L10K|0.728058063 -MSIQHFRVAKIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3649|beta-lactamase_L197Y|0.727757047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELYTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3650|beta-lactamase_G154Y|0.727537148 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMYDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3651|beta-lactamase_V72L|0.727220495 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKLLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3652|beta-lactamase_A9D|0.726868657 -MSIQHFRVDLIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3653|beta-lactamase_V257Y|0.7257935990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIYVIYTTGSQATMDERNRQIAEIGASLIKHW ->3654|beta-lactamase_T178V|0.725708571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDVTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3655|beta-lactamase_I93H|0.7253899629999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRHHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3656|beta-lactamase_L73N|0.7249648259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVNLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3657|beta-lactamase_N272Q|0.7249648259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERQRQIAEIGASLIKHW ->3658|beta-lactamase_T262F|0.7249648259999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTFGSQATMDERNRQIAEIGASLIKHW ->3659|beta-lactamase_M115R|0.72457976 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGRTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3660|beta-lactamase_I11N|0.724532848 -MSIQHFRVALNPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3661|beta-lactamase_T116Y|0.7239679529999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMYVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3662|beta-lactamase_T178A|0.7235447709999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDATMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3663|beta-lactamase_R59S|0.723130385 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFSPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3664|beta-lactamase_L197C|0.7229564209999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELCTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3665|beta-lactamase_L247A|0.722919283 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAAGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3666|beta-lactamase_I229A|0.7228401190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFAADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3667|beta-lactamase_D212H|0.7223925040000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAHKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3668|beta-lactamase_R91V|0.722115921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGVRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3669|beta-lactamase_F228W|0.7217073979999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWWIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3670|beta-lactamase_A132G|0.7216800329999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTGANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3671|beta-lactamase_A40E|0.721055522 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGERVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3672|beta-lactamase_G76Y|0.720522879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCYAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3673|beta-lactamase_E35C|0.720522879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDACDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3674|beta-lactamase_D48V|0.7203840990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELVLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3675|beta-lactamase_L49N|0.7200781959999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDNNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3676|beta-lactamase_S233P|0.720033239 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKPGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3677|beta-lactamase_V21W|0.71972929 -MSIQHFRVALIPFFAAFCLPWFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3678|beta-lactamase_G154L|0.719610057 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMLDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3679|beta-lactamase_D83T|0.7192787429999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVTAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3680|beta-lactamase_F22P|0.719216194 -MSIQHFRVALIPFFAAFCLPVPAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3681|beta-lactamase_I256A|0.718907359 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRAVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3682|beta-lactamase_L49H|0.718674756 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDHNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3683|beta-lactamase_P143I|0.718448993 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGIKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3684|beta-lactamase_Q204G|0.718301417 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQGLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3685|beta-lactamase_L10R|0.7179837859999999 -MSIQHFRVARIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3686|beta-lactamase_L137Q|0.717803958 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLQTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3687|beta-lactamase_I11R|0.717371003 -MSIQHFRVALRPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3688|beta-lactamase_E87G|0.717283043 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQGQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3689|beta-lactamase_I93T|0.717191175 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRTHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3690|beta-lactamase_V214P|0.717010369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKPAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3691|beta-lactamase_P249G|0.716413223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGGDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3692|beta-lactamase_A230L|0.7163418779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFILDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3693|beta-lactamase_L197S|0.7163418779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELSTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3694|beta-lactamase_G76W|0.716079955 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCWAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3695|beta-lactamase_L167G|0.715963653 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEGNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3696|beta-lactamase_D174A|0.715945084 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNAERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3697|beta-lactamase_M67E|0.714385272 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMESTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3698|beta-lactamase_W286I|0.71332976 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHI ->3699|beta-lactamase_H110D|0.713078587 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKDLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3700|beta-lactamase_K30D|0.7127482509999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVDVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3701|beta-lactamase_N130D|0.71210517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDDTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3702|beta-lactamase_G39P|0.711638008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLPARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3703|beta-lactamase_L197N|0.711181597 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELNTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3704|beta-lactamase_L192S|0.710165178 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLSTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3705|beta-lactamase_R202L|0.710062559 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASLQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3706|beta-lactamase_R255T|0.709873935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSTIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3707|beta-lactamase_N134T|0.7095641220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAATLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3708|beta-lactamase_P20C|0.709533825 -MSIQHFRVALIPFFAAFCLCVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3709|beta-lactamase_L49Q|0.7094165459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDQNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3710|beta-lactamase_G76I|0.708675733 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCIAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3711|beta-lactamase_P165Y|0.708675733 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEYELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3712|beta-lactamase_Y103D|0.708675733 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEDSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3713|beta-lactamase_A23E|0.708675733 -MSIQHFRVALIPFFAAFCLPVFEHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3714|beta-lactamase_A215Q|0.707707203 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVQGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3715|beta-lactamase_R241G|0.707121785 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSGGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3716|beta-lactamase_A40D|0.7064552479999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGDRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3717|beta-lactamase_G216P|0.7064298379999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAPPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3718|beta-lactamase_P249F|0.706034998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGFDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3719|beta-lactamase_H110I|0.705714435 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKILTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3720|beta-lactamase_D99P|0.70560302 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNPLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3721|beta-lactamase_P165W|0.7055521990000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEWELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3722|beta-lactamase_Q274P|0.705418305 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRPIAEIGASLIKHW ->3723|beta-lactamase_T131Y|0.7040217059999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNYAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3724|beta-lactamase_L197T|0.703929838 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELTTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3725|beta-lactamase_A215N|0.70386338 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVNGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3726|beta-lactamase_A215K|0.70375001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVKGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3727|beta-lactamase_D231S|0.703664005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIASKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3728|beta-lactamase_V82D|0.703211503 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRDDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3729|beta-lactamase_S264R|0.7027531370000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGRQATMDERNRQIAEIGASLIKHW ->3730|beta-lactamase_P20A|0.7024443020000001 -MSIQHFRVALIPFFAAFCLAVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3731|beta-lactamase_N168H|0.702225381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELHEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3732|beta-lactamase_N168L|0.7021608779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELLEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3733|beta-lactamase_V214E|0.702059236 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKEAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3734|beta-lactamase_V258G|0.702003528 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVGIYTTGSQATMDERNRQIAEIGASLIKHW ->3735|beta-lactamase_G141I|0.7018178359999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIIGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3736|beta-lactamase_I11K|0.7014640440000001 -MSIQHFRVALKPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3737|beta-lactamase_I11Q|0.699833864 -MSIQHFRVALQPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3738|beta-lactamase_N130G|0.698495905 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDGTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3739|beta-lactamase_I45H|0.698437265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYHELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3740|beta-lactamase_P224C|0.698420651 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALCAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3741|beta-lactamase_C121S|0.698167523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELSSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3742|beta-lactamase_R162L|0.698167523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDLWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3743|beta-lactamase_G52W|0.69808836 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSWKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3744|beta-lactamase_I93E|0.6980570859999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRREHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3745|beta-lactamase_P181S|0.6975488759999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMSAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3746|beta-lactamase_Y95H|0.697230268 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHHSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3747|beta-lactamase_G279V|0.696674169 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIVASLIKHW ->3748|beta-lactamase_A124I|0.695950948 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAIITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3749|beta-lactamase_E164Y|0.695645045 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWYPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3750|beta-lactamase_G239S|0.6955150609999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERSSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3751|beta-lactamase_G76L|0.6951016520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCLAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3752|beta-lactamase_L89N|0.6947361320000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQNGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3753|beta-lactamase_S264V|0.694714631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGVQATMDERNRQIAEIGASLIKHW ->3754|beta-lactamase_L191H|0.694319791 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKHLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3755|beta-lactamase_R91G|0.693820377 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGGRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3756|beta-lactamase_A23R|0.692055326 -MSIQHFRVALIPFFAAFCLPVFRHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3757|beta-lactamase_F70Y|0.691530502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTYKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3758|beta-lactamase_A245V|0.6914767490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIVALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3759|beta-lactamase_F58G|0.691134685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESGRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3760|beta-lactamase_F149G|0.6909157640000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAGLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3761|beta-lactamase_L100R|0.690471081 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDRVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3762|beta-lactamase_G279M|0.690060604 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIMASLIKHW ->3763|beta-lactamase_Q274D|0.690060604 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRDIAEIGASLIKHW ->3764|beta-lactamase_A16R|0.690060604 -MSIQHFRVALIPFFARFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3765|beta-lactamase_A215E|0.689554349 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVEGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3766|beta-lactamase_A215H|0.689425342 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVHGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3767|beta-lactamase_F64V|0.689014865 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERVPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3768|beta-lactamase_T27K|0.688916155 -MSIQHFRVALIPFFAAFCLPVFAHPEKLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3769|beta-lactamase_S264I|0.688736327 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGIQATMDERNRQIAEIGASLIKHW ->3770|beta-lactamase_G76F|0.6883151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCFAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3771|beta-lactamase_P105G|0.6878938720000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSGVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3772|beta-lactamase_R220Q|0.68775216 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLQSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3773|beta-lactamase_D212A|0.6864220190000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAAKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3774|beta-lactamase_E119C|0.6852609559999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRCLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3775|beta-lactamase_Y103I|0.685189611 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEISPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3776|beta-lactamase_G114W|0.684983395 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDWMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3777|beta-lactamase_N130Q|0.684983395 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDQTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3778|beta-lactamase_Y103L|0.684983395 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVELSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3779|beta-lactamase_V257F|0.6836161159999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIFVIYTTGSQATMDERNRQIAEIGASLIKHW ->3780|beta-lactamase_G142Q|0.6836161159999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGQPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3781|beta-lactamase_D212P|0.683337578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAPKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3782|beta-lactamase_D212K|0.682872371 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAKKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3783|beta-lactamase_A15E|0.6826690870000001 -MSIQHFRVALIPFFEAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3784|beta-lactamase_E87H|0.682472645 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQHQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3785|beta-lactamase_G263F|0.682206812 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTFSQATMDERNRQIAEIGASLIKHW ->3786|beta-lactamase_G236D|0.682168696 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGADERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3787|beta-lactamase_I54G|0.68197714 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKGLESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3788|beta-lactamase_Y95P|0.681682965 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHPSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3789|beta-lactamase_Y103Q|0.681528548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEQSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3790|beta-lactamase_E56F|0.680985154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILFSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3791|beta-lactamase_E26E|0.6804126490000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3792|beta-lactamase_D212C|0.68029614 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEACKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3793|beta-lactamase_R118P|0.679251378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVPELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3794|beta-lactamase_I45E|0.676098524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYEELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3795|beta-lactamase_A246H|0.676098524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAHLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3796|beta-lactamase_G142H|0.676098524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGHPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3797|beta-lactamase_E35M|0.676098524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAMDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3798|beta-lactamase_L100H|0.676098524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDHVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3799|beta-lactamase_L55D|0.676098524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIDESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3800|beta-lactamase_F17E|0.676098524 -MSIQHFRVALIPFFAAECLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3801|beta-lactamase_A215R|0.6757398459999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVRGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3802|beta-lactamase_D212R|0.674417523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEARKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3803|beta-lactamase_G85I|0.6743051309999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAIQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3804|beta-lactamase_D48L|0.673714826 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELLLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3805|beta-lactamase_E35V|0.672400323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAVDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3806|beta-lactamase_N272C|0.67218922 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERCRQIAEIGASLIKHW ->3807|beta-lactamase_G263W|0.671722058 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTWSQATMDERNRQIAEIGASLIKHW ->3808|beta-lactamase_G52P|0.671656577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSPKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3809|beta-lactamase_D83N|0.671485545 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVNAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3810|beta-lactamase_E46R|0.671211894 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIRLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3811|beta-lactamase_G279I|0.671086796 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIIASLIKHW ->3812|beta-lactamase_L146Q|0.6705492670000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEQTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3813|beta-lactamase_G114K|0.669435115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDKMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3814|beta-lactamase_L167P|0.66894743 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEPNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3815|beta-lactamase_A15K|0.668357125 -MSIQHFRVALIPFFKAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3816|beta-lactamase_N272H|0.6681206120000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERHRQIAEIGASLIKHW ->3817|beta-lactamase_D231H|0.668075655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAHKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3818|beta-lactamase_L167Q|0.668075655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEQNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3819|beta-lactamase_A40I|0.667475577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGIRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3820|beta-lactamase_D177N|0.667411073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERNTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3821|beta-lactamase_L219P|0.667191175 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLPRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3822|beta-lactamase_A23T|0.665239455 -MSIQHFRVALIPFFAAFCLPVFTHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3823|beta-lactamase_G239A|0.665068423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERASRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3824|beta-lactamase_S264D|0.664180033 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGDQATMDERNRQIAEIGASLIKHW ->3825|beta-lactamase_F228E|0.664018774 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWEIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3826|beta-lactamase_S264F|0.663881949 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGFQATMDERNRQIAEIGASLIKHW ->3827|beta-lactamase_T116F|0.663881949 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMFVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3828|beta-lactamase_W286L|0.663555522 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHL ->3829|beta-lactamase_L197A|0.663375694 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELATLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3830|beta-lactamase_P143N|0.663067836 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGNKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3831|beta-lactamase_R162R|0.662401288 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3832|beta-lactamase_P105W|0.6621364439999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSWVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3833|beta-lactamase_L89K|0.6613369920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQKGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3834|beta-lactamase_S264E|0.661291057 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGEQATMDERNRQIAEIGASLIKHW ->3835|beta-lactamase_V29P|0.661226554 -MSIQHFRVALIPFFAAFCLPVFAHPETLPKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3836|beta-lactamase_G142A|0.6611903929999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGAPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3837|beta-lactamase_D231G|0.661070182 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAGKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3838|beta-lactamase_T27D|0.661062363 -MSIQHFRVALIPFFAAFCLPVFAHPEDLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3839|beta-lactamase_L135S|0.660937265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANSLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3840|beta-lactamase_L100S|0.660461308 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDSVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3841|beta-lactamase_I243W|0.6601886339999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGWIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3842|beta-lactamase_S201F|0.659809431 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAFRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3843|beta-lactamase_D231E|0.659692152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAEKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3844|beta-lactamase_P65N|0.65873535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFNMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3845|beta-lactamase_M1V|0.658723622 -VSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3846|beta-lactamase_G114C|0.6586464129999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDCMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3847|beta-lactamase_V42N|0.658529134 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARNGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3848|beta-lactamase_G154P|0.658474404 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMPDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3849|beta-lactamase_M115S|0.658000401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGSTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3850|beta-lactamase_A40F|0.658000401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGFRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3851|beta-lactamase_A245M|0.657182379 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIMALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3852|beta-lactamase_G263P|0.657182379 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTPSQATMDERNRQIAEIGASLIKHW ->3853|beta-lactamase_K213P|0.657084646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADPVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3854|beta-lactamase_V117C|0.657028939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTCRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3855|beta-lactamase_F14H|0.657028939 -MSIQHFRVALIPFHAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3856|beta-lactamase_G279L|0.656552004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEILASLIKHW ->3857|beta-lactamase_L191Q|0.655715412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKQLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3858|beta-lactamase_R271F|0.65450646 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEFNRQIAEIGASLIKHW ->3859|beta-lactamase_L218V|0.654105756 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPVLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3860|beta-lactamase_R241Q|0.6536757329999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSQGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3861|beta-lactamase_R91W|0.6534529029999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGWRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3862|beta-lactamase_G141V|0.653294576 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIVGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3863|beta-lactamase_L47K|0.6526426989999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEKDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3864|beta-lactamase_L160P|0.65230259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRPDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3865|beta-lactamase_M184Q|0.6516653729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAQATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3866|beta-lactamase_S51I|0.6516653729999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNIGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3867|beta-lactamase_D231M|0.651371198 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAMKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3868|beta-lactamase_M67F|0.6511669370000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMFSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3869|beta-lactamase_R91C|0.650917719 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGCRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3870|beta-lactamase_R59C|0.650905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFCPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3871|beta-lactamase_L49K|0.64974395 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDKNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3872|beta-lactamase_N134K|0.649720495 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAKLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3873|beta-lactamase_D174M|0.649249423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNMERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3874|beta-lactamase_G263V|0.649034412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTVSQATMDERNRQIAEIGASLIKHW ->3875|beta-lactamase_R59M|0.648950362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFMPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3876|beta-lactamase_P65H|0.6489317920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFHMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3877|beta-lactamase_N134H|0.648611229 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAHLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3878|beta-lactamase_A40H|0.6484079460000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGHRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3879|beta-lactamase_P65V|0.648343442 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFVMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3880|beta-lactamase_R220A|0.6482075939999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLASALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3881|beta-lactamase_A123I|0.648175342 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSIAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3882|beta-lactamase_I259Y|0.647140354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVYYTTGSQATMDERNRQIAEIGASLIKHW ->3883|beta-lactamase_L100A|0.6467787429999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDAVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3884|beta-lactamase_G141L|0.645768188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTILGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3885|beta-lactamase_G154F|0.645001964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMFDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3886|beta-lactamase_V78F|0.6447742470000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAFLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3887|beta-lactamase_L137E|0.644517211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLETTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3888|beta-lactamase_D231T|0.64363664 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIATKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3889|beta-lactamase_S264Y|0.642664201 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGYQATMDERNRQIAEIGASLIKHW ->3890|beta-lactamase_D231C|0.642649541 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIACKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3891|beta-lactamase_R159G|0.6424315970000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTGLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3892|beta-lactamase_V117A|0.64241205 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTARELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3893|beta-lactamase_V29Y|0.639448798 -MSIQHFRVALIPFFAAFCLPVFAHPETLYKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3894|beta-lactamase_G114D|0.638144068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDDMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3895|beta-lactamase_A235Q|0.637616312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGQGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3896|beta-lactamase_L74E|0.637227336 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLECGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3897|beta-lactamase_D212E|0.6359431289999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAEKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3898|beta-lactamase_L79F|0.635424169 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVFSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3899|beta-lactamase_T69P|0.635172996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSPFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3900|beta-lactamase_L150H|0.6348856629999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFHHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3901|beta-lactamase_L136C|0.634749814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLCLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3902|beta-lactamase_F13K|0.634510369 -MSIQHFRVALIPKFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3903|beta-lactamase_L146T|0.633944498 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKETTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3904|beta-lactamase_G141F|0.6337959439999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIFGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3905|beta-lactamase_I140N|0.632773661 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTNGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3906|beta-lactamase_A123N|0.6324511429999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSNAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3907|beta-lactamase_D174V|0.631816859 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNVERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3908|beta-lactamase_T126W|0.631675147 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIWMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3909|beta-lactamase_L192Q|0.631237305 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLQTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3910|beta-lactamase_V117P|0.631110252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTPRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3911|beta-lactamase_T116G|0.631076046 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMGVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3912|beta-lactamase_R91I|0.631028157 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGIRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3913|beta-lactamase_A215C|0.630866898 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVCGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3914|beta-lactamase_R241N|0.630669478 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSNGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3915|beta-lactamase_T126Y|0.6306616589999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIYMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3916|beta-lactamase_W286H|0.630351847 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHH ->3917|beta-lactamase_R255A|0.6297507920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSAIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3918|beta-lactamase_I93A|0.62974786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRAHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3919|beta-lactamase_L120T|0.629267993 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRETCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3920|beta-lactamase_V258S|0.629186875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVSIYTTGSQATMDERNRQIAEIGASLIKHW ->3921|beta-lactamase_A123Y|0.629186875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSYAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3922|beta-lactamase_N134S|0.6286855060000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAASLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3923|beta-lactamase_I125A|0.626413223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAATMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3924|beta-lactamase_D231I|0.626404427 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAIKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3925|beta-lactamase_H285I|0.62623535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKIW ->3926|beta-lactamase_L192H|0.626146413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLHTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3927|beta-lactamase_R241H|0.626050635 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3928|beta-lactamase_N134R|0.6257320270000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAARLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3929|beta-lactamase_L79C|0.625698798 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVCSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3930|beta-lactamase_I243T|0.625638204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGTIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3931|beta-lactamase_A211P|0.624949189 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEPDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3932|beta-lactamase_D174H|0.62488664 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNHERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3933|beta-lactamase_P105D|0.6246599 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSDVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3934|beta-lactamase_G52V|0.624544576 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSVKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3935|beta-lactamase_R59Y|0.623974795 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFYPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3936|beta-lactamase_L135R|0.623099111 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANRLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3937|beta-lactamase_D155E|0.622790276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGEHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3938|beta-lactamase_N152P|0.622502942 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHPMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3939|beta-lactamase_T131H|0.6223455920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNHAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3940|beta-lactamase_L167F|0.621802199 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEFNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3941|beta-lactamase_T158V|0.6213682660000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVVRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3942|beta-lactamase_L137G|0.62135947 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLGTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3943|beta-lactamase_D83K|0.620435897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVKAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3944|beta-lactamase_L197E|0.6202511829999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELETLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3945|beta-lactamase_D161Y|0.619088165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLYRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3946|beta-lactamase_P65C|0.6189669760000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFCMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3947|beta-lactamase_P249W|0.618183161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGWDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3948|beta-lactamase_A215Y|0.617817641 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVYGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3949|beta-lactamase_D231V|0.61735732 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAVKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3950|beta-lactamase_N272V|0.616866703 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERVRQIAEIGASLIKHW ->3951|beta-lactamase_Q37P|0.6164650220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDPLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3952|beta-lactamase_R220S|0.616380971 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLSSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3953|beta-lactamase_L219D|0.615740823 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLDRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3954|beta-lactamase_L197G|0.6154231920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELGTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3955|beta-lactamase_D48K|0.615015647 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELKLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3956|beta-lactamase_T198W|0.614731245 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLWLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3957|beta-lactamase_M66Y|0.614372566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPYMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3958|beta-lactamase_R63W|0.614227922 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEWFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3959|beta-lactamase_L188G|0.614057867 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTGRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3960|beta-lactamase_S264L|0.613973817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGLQATMDERNRQIAEIGASLIKHW ->3961|beta-lactamase_D174P|0.613879017 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNPERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3962|beta-lactamase_P224L|0.613820377 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALLAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3963|beta-lactamase_P181I|0.613247664 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMIAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3964|beta-lactamase_E195L|0.612859666 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGLLLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3965|beta-lactamase_L219C|0.612217563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLCRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3966|beta-lactamase_V117F|0.611801222 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTFRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3967|beta-lactamase_D231L|0.611532457 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIALKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3968|beta-lactamase_M153D|0.610943129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNDGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3969|beta-lactamase_D83H|0.6099228010000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVHAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3970|beta-lactamase_L218G|0.609864161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPGLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3971|beta-lactamase_D231Y|0.609341292 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAYKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3972|beta-lactamase_L137N|0.609262129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLNTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3973|beta-lactamase_I140G|0.609201534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTGGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3974|beta-lactamase_G52C|0.608507633 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSCKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3975|beta-lactamase_R63G|0.608119634 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEGFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3976|beta-lactamase_L160G|0.608020925 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRGDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3977|beta-lactamase_G114T|0.607685702 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDTMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3978|beta-lactamase_D48Y|0.607111034 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELYLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3979|beta-lactamase_A215V|0.606422996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVVGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3980|beta-lactamase_R241A|0.6058727620000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSAGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3981|beta-lactamase_T261W|0.605514083 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYWTGSQATMDERNRQIAEIGASLIKHW ->3982|beta-lactamase_L188W|0.605068423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTWRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3983|beta-lactamase_E46W|0.604428274 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIWLDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3984|beta-lactamase_R241C|0.603989455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSCGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3985|beta-lactamase_I278F|0.603277961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEFGASLIKHW ->3986|beta-lactamase_L135H|0.6030981329999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANHLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3987|beta-lactamase_D161I|0.602915373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLIRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3988|beta-lactamase_N168E|0.602422801 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELEEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3989|beta-lactamase_N134M|0.602138399 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAMLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3990|beta-lactamase_D48I|0.601391722 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELILNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3991|beta-lactamase_L219W|0.601361425 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLWRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3992|beta-lactamase_T147W|0.601239259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELWAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3993|beta-lactamase_D231P|0.6004720579999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAPKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3994|beta-lactamase_L282E|0.60043492 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASEIKHW ->3995|beta-lactamase_P224Y|0.600372371 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALYAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3996|beta-lactamase_A123E|0.598842856 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSEAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3997|beta-lactamase_S104V|0.598470495 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYVPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3998|beta-lactamase_R241M|0.598243755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSMGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->3999|beta-lactamase_L218F|0.597700362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPFLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4000|beta-lactamase_R59G|0.597282066 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFGPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4001|beta-lactamase_N134C|0.596982027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAACLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4002|beta-lactamase_P105C|0.596982027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSCVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4003|beta-lactamase_L120F|0.596948798 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREFCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4004|beta-lactamase_S201V|0.59692241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAVRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4005|beta-lactamase_A124N|0.596690784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSANITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4006|beta-lactamase_D212V|0.5964337470000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAVKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4007|beta-lactamase_Y103R|0.595000987 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVERSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4008|beta-lactamase_T187W|0.5948377739999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATWLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4009|beta-lactamase_A266P|0.594247469 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQPTMDERNRQIAEIGASLIKHW ->4010|beta-lactamase_D231K|0.593914201 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAKKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4011|beta-lactamase_L219K|0.59355259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLKRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4012|beta-lactamase_G142C|0.5930258110000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGCPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4013|beta-lactamase_G263I|0.592738477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTISQATMDERNRQIAEIGASLIKHW ->4014|beta-lactamase_A235I|0.592254701 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGIGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4015|beta-lactamase_D174L|0.5922507920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNLERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4016|beta-lactamase_P65K|0.592057281 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFKMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4017|beta-lactamase_N134A|0.591846179 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAALLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4018|beta-lactamase_L218T|0.59126467 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPTLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4019|beta-lactamase_R220H|0.589559236 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLHSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4020|beta-lactamase_P143R|0.589499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGRKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4021|beta-lactamase_N134V|0.587400323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAVLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4022|beta-lactamase_L136T|0.587368071 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLTLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4023|beta-lactamase_R220G|0.5873622070000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLGSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4024|beta-lactamase_P20M|0.5872507920000001 -MSIQHFRVALIPFFAAFCLMVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4025|beta-lactamase_P181G|0.587225381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMGAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4026|beta-lactamase_I283G|0.587112011 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLGKHW ->4027|beta-lactamase_G114L|0.586864748 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDLMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4028|beta-lactamase_G142K|0.5867425820000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGKPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4029|beta-lactamase_A34K|0.5865099779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDKEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4030|beta-lactamase_L218A|0.586477727 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPALRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4031|beta-lactamase_G114E|0.58629008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDEMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4032|beta-lactamase_G239H|0.5857418000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERHSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4033|beta-lactamase_T27F|0.585346961 -MSIQHFRVALIPFFAAFCLPVFAHPEFLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4034|beta-lactamase_T139P|0.585346961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTPIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4035|beta-lactamase_I93K|0.584588556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRKHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4036|beta-lactamase_T147Y|0.584314904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELYAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4037|beta-lactamase_G154V|0.5841145520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMVDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4038|beta-lactamase_A124L|0.5839503620000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSALITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4039|beta-lactamase_Y260T|0.582690588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVITTTGSQATMDERNRQIAEIGASLIKHW ->4040|beta-lactamase_P224M|0.582646609 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALMAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4041|beta-lactamase_G154W|0.582275225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMWDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4042|beta-lactamase_P143M|0.5813731529999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGMKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4043|beta-lactamase_G43C|0.580856147 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVCYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4044|beta-lactamase_I243A|0.58082585 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGAIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4045|beta-lactamase_I140E|0.579668696 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTEGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4046|beta-lactamase_S264W|0.5796520820000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGWQATMDERNRQIAEIGASLIKHW ->4047|beta-lactamase_T187E|0.579084255 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATELRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4048|beta-lactamase_I229Y|0.578923974 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFYADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4049|beta-lactamase_D83C|0.578899541 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVCAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4050|beta-lactamase_G114Q|0.5783659210000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDQMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4051|beta-lactamase_P143L|0.5783659210000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGLKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4052|beta-lactamase_L100E|0.5783659210000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDEVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4053|beta-lactamase_A23Y|0.5783659210000001 -MSIQHFRVALIPFFAAFCLPVFYHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4054|beta-lactamase_L10E|0.5783659210000001 -MSIQHFRVAEIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4055|beta-lactamase_R176P|0.577950557 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDEPDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4056|beta-lactamase_H151P|0.577636835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLPNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4057|beta-lactamase_L188H|0.57748535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTHRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4058|beta-lactamase_I140H|0.576862793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTHGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4059|beta-lactamase_R59L|0.576750401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFLPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4060|beta-lactamase_L191S|0.576703489 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKSLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4061|beta-lactamase_I259A|0.576521706 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVAYTTGSQATMDERNRQIAEIGASLIKHW ->4062|beta-lactamase_N134I|0.576426906 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAILLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4063|beta-lactamase_R59W|0.576411269 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFWPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4064|beta-lactamase_L73D|0.576391722 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVDLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4065|beta-lactamase_M115F|0.576169869 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGFTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4066|beta-lactamase_G142R|0.576005678 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGRPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4067|beta-lactamase_K109K|0.575988533 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4068|beta-lactamase_R241V|0.575442738 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSVGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4069|beta-lactamase_G226V|0.574890549 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAVWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4070|beta-lactamase_I278C|0.5746774920000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAECGASLIKHW ->4071|beta-lactamase_D48R|0.57425431 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELRLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4072|beta-lactamase_T178I|0.573805717 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDITMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4073|beta-lactamase_T69I|0.5736473910000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSIFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4074|beta-lactamase_N134Y|0.57317241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAYLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4075|beta-lactamase_P65T|0.5710711589999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFTMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4076|beta-lactamase_I206D|0.571035975 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLDDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4077|beta-lactamase_L197P|0.571009588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELPTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4078|beta-lactamase_D36Q|0.570221863 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEQQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4079|beta-lactamase_L137W|0.568884881 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLWTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4080|beta-lactamase_Y260C|0.568342465 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVICTTGSQATMDERNRQIAEIGASLIKHW ->4081|beta-lactamase_L219Q|0.56830044 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLQRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4082|beta-lactamase_T131N|0.568255483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNNAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4083|beta-lactamase_R220V|0.568219322 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLVSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4084|beta-lactamase_L219S|0.56772284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLSRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4085|beta-lactamase_P224V|0.567632926 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALVAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4086|beta-lactamase_V117N|0.56686768 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTNRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4087|beta-lactamase_L79A|0.566562754 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVASRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4088|beta-lactamase_C121V|0.56642886 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELVSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4089|beta-lactamase_Y95A|0.5663545839999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHASQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4090|beta-lactamase_Y44H|0.565961699 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGHIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4091|beta-lactamase_R271Y|0.565955835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEYNRQIAEIGASLIKHW ->4092|beta-lactamase_R255C|0.565755483 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSCIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4093|beta-lactamase_I229F|0.564992191 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFFADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4094|beta-lactamase_P20V|0.564403841 -MSIQHFRVALIPFFAAFCLVVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4095|beta-lactamase_R255Q|0.563827219 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSQIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4096|beta-lactamase_L135Y|0.563824287 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANYLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4097|beta-lactamase_D231F|0.563822332 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAFKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4098|beta-lactamase_I259T|0.5638194000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVTYTTGSQATMDERNRQIAEIGASLIKHW ->4099|beta-lactamase_I283E|0.56370603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLEKHW ->4100|beta-lactamase_M66S|0.563362989 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPSMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4101|beta-lactamase_T27G|0.56293492 -MSIQHFRVALIPFFAAFCLPVFAHPEGLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4102|beta-lactamase_E35R|0.562897781 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDARDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4103|beta-lactamase_A235C|0.562728704 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGCGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4104|beta-lactamase_A185T|0.561741605 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMTTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4105|beta-lactamase_L47H|0.560596179 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEHDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4106|beta-lactamase_I93W|0.560432965 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRWHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4107|beta-lactamase_L219A|0.560290276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLARSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4108|beta-lactamase_E35T|0.5602677970000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDATDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4109|beta-lactamase_M115Y|0.5600410570000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGYTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4110|beta-lactamase_R255S|0.559824091 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSSIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4111|beta-lactamase_N168R|0.5597048570000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELREAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4112|beta-lactamase_T147P|0.55970388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELPAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4113|beta-lactamase_P143F|0.559449775 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGFKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4114|beta-lactamase_A245L|0.559284607 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIILALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4115|beta-lactamase_D83M|0.559202512 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVMAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4116|beta-lactamase_S104R|0.559028548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYRPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4117|beta-lactamase_E195I|0.5588194000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGILLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4118|beta-lactamase_L219N|0.5586815970000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLNRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4119|beta-lactamase_L49E|0.558081519 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDENSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4120|beta-lactamase_D174I|0.557834255 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNIERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4121|beta-lactamase_P65I|0.557450166 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFIMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4122|beta-lactamase_L282G|0.557348524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASGIKHW ->4123|beta-lactamase_L218P|0.557219517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPPLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4124|beta-lactamase_L219E|0.55711983 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLERSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4125|beta-lactamase_Y95C|0.556509978 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHCSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4126|beta-lactamase_L135N|0.556091683 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANNLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4127|beta-lactamase_L47W|0.556003724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEWDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4128|beta-lactamase_L167H|0.55591381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEHNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4129|beta-lactamase_L89R|0.555862011 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQRGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4130|beta-lactamase_R63D|0.555758415 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEDFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4131|beta-lactamase_E270P|0.555370416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDPRNRQIAEIGASLIKHW ->4132|beta-lactamase_D161F|0.554995123 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLFRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4133|beta-lactamase_E35N|0.554775225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDANDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4134|beta-lactamase_S233V|0.554250401 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKVGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4135|beta-lactamase_G248H|0.55393277 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALHPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4136|beta-lactamase_L49R|0.553277961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDRNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4137|beta-lactamase_G239C|0.5532242079999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERCSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4138|beta-lactamase_W286N|0.553027766 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHN ->4139|beta-lactamase_N134F|0.5525498529999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAFLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4140|beta-lactamase_L146G|0.5520289389999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEGTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4141|beta-lactamase_D161G|0.5519185010000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLGRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4142|beta-lactamase_W208E|0.551821746 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDEMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4143|beta-lactamase_R271W|0.551333082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDEWNRQIAEIGASLIKHW ->4144|beta-lactamase_M209A|0.551091683 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWAEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4145|beta-lactamase_L167E|0.55074571 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEENEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4146|beta-lactamase_P65G|0.549432183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFGMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4147|beta-lactamase_F64W|0.548941566 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERWPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4148|beta-lactamase_G236G|0.548745027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4149|beta-lactamase_L223N|0.548444107 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSANPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4150|beta-lactamase_R202W|0.548379603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASWQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4151|beta-lactamase_I93M|0.548294576 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRMHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4152|beta-lactamase_T27R|0.547771706 -MSIQHFRVALIPFFAAFCLPVFAHPERLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4153|beta-lactamase_A230W|0.547146218 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIWDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4154|beta-lactamase_S240M|0.546994732 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGMRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4155|beta-lactamase_L223G|0.546665373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAGPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4156|beta-lactamase_T126F|0.545788712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIFMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4157|beta-lactamase_I140W|0.545788712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTWGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4158|beta-lactamase_I243E|0.54571639 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGEIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4159|beta-lactamase_I45G|0.545254115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYGELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4160|beta-lactamase_T261G|0.54453578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYGTGSQATMDERNRQIAEIGASLIKHW ->4161|beta-lactamase_G236C|0.544236718 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGACERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4162|beta-lactamase_V257S|0.5439875 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRISVIYTTGSQATMDERNRQIAEIGASLIKHW ->4163|beta-lactamase_W286Q|0.543461699 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHQ ->4164|beta-lactamase_L247Y|0.543357125 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAYGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4165|beta-lactamase_L219R|0.5433082579999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLRRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4166|beta-lactamase_R220T|0.5426358579999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLTSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4167|beta-lactamase_A215M|0.542110057 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVMGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4168|beta-lactamase_K190P|0.541955639 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRPLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4169|beta-lactamase_V31S|0.5418158820000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKSKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4170|beta-lactamase_L47G|0.541345788 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEGDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4171|beta-lactamase_G114P|0.540776984 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDPMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4172|beta-lactamase_A123H|0.540776984 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSHAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4173|beta-lactamase_W208C|0.540123153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDCMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4174|beta-lactamase_P143K|0.538857516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGKKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4175|beta-lactamase_A34H|0.538745123 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDHEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4176|beta-lactamase_D231R|0.538697234 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIARKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4177|beta-lactamase_P20Y|0.538548681 -MSIQHFRVALIPFFAAFCLYVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4178|beta-lactamase_G279Y|0.53838449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIYASLIKHW ->4179|beta-lactamase_L223W|0.538239846 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAWPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4180|beta-lactamase_I244F|0.538233982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIFAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4181|beta-lactamase_L28I|0.537643677 -MSIQHFRVALIPFFAAFCLPVFAHPETIVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4182|beta-lactamase_D83V|0.5371980160000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVVAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4183|beta-lactamase_G279W|0.536480659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIWASLIKHW ->4184|beta-lactamase_C121T|0.535873739 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELTSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4185|beta-lactamase_T178M|0.535823896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDMTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4186|beta-lactamase_T131P|0.535805326 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNPAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4187|beta-lactamase_T107N|0.5352482510000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVNEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4188|beta-lactamase_P224F|0.535236523 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALFAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4189|beta-lactamase_Y103E|0.535181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEESPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4190|beta-lactamase_L219H|0.535123153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLHRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4191|beta-lactamase_S281P|0.53508406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGAPLIKHW ->4192|beta-lactamase_W227M|0.534749814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGMFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4193|beta-lactamase_L79Q|0.534618853 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVQSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4194|beta-lactamase_D177C|0.534037344 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERCTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4195|beta-lactamase_V78S|0.5340099779999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGASLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4196|beta-lactamase_A123M|0.533942543 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSMAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4197|beta-lactamase_N134G|0.533729486 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAGLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4198|beta-lactamase_R241L|0.532971081 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSLGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4199|beta-lactamase_I244S|0.5327873439999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGISAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4200|beta-lactamase_P253Y|0.532757047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKYSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4201|beta-lactamase_T261K|0.5326192439999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYKTGSQATMDERNRQIAEIGASLIKHW ->4202|beta-lactamase_L205C|0.532443325 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQCIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4203|beta-lactamase_R162F|0.532214631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDFWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4204|beta-lactamase_L218D|0.532094419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPDLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4205|beta-lactamase_N272I|0.531826632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERIRQIAEIGASLIKHW ->4206|beta-lactamase_A40K|0.5317826520000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGKRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4207|beta-lactamase_T178Q|0.53147284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDQTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4208|beta-lactamase_L197W|0.531184529 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELWTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4209|beta-lactamase_M184T|0.530752551 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAATATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4210|beta-lactamase_A215I|0.5306254979999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVIGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4211|beta-lactamase_A185I|0.5303567339999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMITTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4212|beta-lactamase_I275T|0.530288321 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQTAEIGASLIKHW ->4213|beta-lactamase_D83R|0.53020818 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVRAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4214|beta-lactamase_P224I|0.529847547 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALIAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4215|beta-lactamase_L205W|0.529499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQWIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4216|beta-lactamase_L219T|0.529499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLTRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4217|beta-lactamase_Y44W|0.529499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGWIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4218|beta-lactamase_S201W|0.529499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAWRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4219|beta-lactamase_D33F|0.529499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKFAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4220|beta-lactamase_R59F|0.529499619 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFFPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4221|beta-lactamase_G248S|0.52891811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALSPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4222|beta-lactamase_P181L|0.528838946 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMLAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4223|beta-lactamase_D174R|0.528770534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNRERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4224|beta-lactamase_I283N|0.528611229 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLNKHW ->4225|beta-lactamase_V78E|0.5277834339999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAELSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4226|beta-lactamase_N168W|0.52772284 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELWEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4227|beta-lactamase_F13N|0.527434529 -MSIQHFRVALIPNFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4228|beta-lactamase_A246K|0.527413028 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAKLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4229|beta-lactamase_T178G|0.526996687 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDGTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4230|beta-lactamase_Y95T|0.5263194 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHTSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4231|beta-lactamase_R220N|0.52563234 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLNSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4232|beta-lactamase_W208N|0.525427101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDNMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4233|beta-lactamase_W208A|0.525220885 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDAMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4234|beta-lactamase_S201P|0.5248895720000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAPRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4235|beta-lactamase_I45R|0.524876867 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYRELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4236|beta-lactamase_L282N|0.5247234270000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASNIKHW ->4237|beta-lactamase_D212Y|0.524693129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAYKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4238|beta-lactamase_I93R|0.524134099 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRRHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4239|beta-lactamase_R255E|0.524069595 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSEIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4240|beta-lactamase_V117Q|0.523750987 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTQRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4241|beta-lactamase_M115K|0.5235623629999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGKTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4242|beta-lactamase_R59E|0.523391331 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFEPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4243|beta-lactamase_I125N|0.5232349589999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAANTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4244|beta-lactamase_P65Q|0.522784412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFQMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4245|beta-lactamase_A84P|0.522071941 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDPGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4246|beta-lactamase_L218N|0.521881362 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPNLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4247|beta-lactamase_R220F|0.521846179 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLFSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4248|beta-lactamase_I259W|0.521355561 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVWYTTGSQATMDERNRQIAEIGASLIKHW ->4249|beta-lactamase_T179A|0.520886444 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTAMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4250|beta-lactamase_A40Y|0.520614748 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGYRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4251|beta-lactamase_W208I|0.520450557 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDIMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4252|beta-lactamase_W208H|0.520388986 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDHMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4253|beta-lactamase_A215F|0.520255092 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVFGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4254|beta-lactamase_L10D|0.520142699 -MSIQHFRVADIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4255|beta-lactamase_F14Q|0.520102629 -MSIQHFRVALIPFQAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4256|beta-lactamase_T131E|0.519726358 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNEAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4257|beta-lactamase_R220C|0.5193246770000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLCSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4258|beta-lactamase_D174Y|0.519212285 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNYERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4259|beta-lactamase_I125S|0.5184832 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAASTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4260|beta-lactamase_E35K|0.518442152 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAKDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4261|beta-lactamase_M115E|0.51835517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGETVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4262|beta-lactamase_L197D|0.5181196339999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELDTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4263|beta-lactamase_E35I|0.5172830429999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAIDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4264|beta-lactamase_A34N|0.517043599 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDNEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4265|beta-lactamase_I93N|0.516998642 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRNHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4266|beta-lactamase_G248A|0.5167279220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALAPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4267|beta-lactamase_A40P|0.51638879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGPRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4268|beta-lactamase_T261N|0.516313536 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYNTGSQATMDERNRQIAEIGASLIKHW ->4269|beta-lactamase_T27E|0.515537539 -MSIQHFRVALIPFFAAFCLPVFAHPEELVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4270|beta-lactamase_S240F|0.515399736 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGFRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4271|beta-lactamase_R162Y|0.5149716670000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDYWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4272|beta-lactamase_G52I|0.514952121 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSIKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4273|beta-lactamase_W208Q|0.5148817529999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDQMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4274|beta-lactamase_V78H|0.514839728 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAHLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4275|beta-lactamase_L100G|0.514839728 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDGVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4276|beta-lactamase_I256Y|0.5147996579999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRYVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4277|beta-lactamase_R241I|0.514766429 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSIGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4278|beta-lactamase_L73E|0.514627649 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVELCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4279|beta-lactamase_T69V|0.513610252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSVFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4280|beta-lactamase_L47R|0.512999423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIERDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4281|beta-lactamase_L137H|0.512724795 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLHTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4282|beta-lactamase_D177G|0.51255474 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERGTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4283|beta-lactamase_I125H|0.5122087670000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAHTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4284|beta-lactamase_A123L|0.5121599 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSLAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4285|beta-lactamase_G226I|0.5120680320000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAIWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4286|beta-lactamase_H110P|0.510797508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKPLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4287|beta-lactamase_I243Q|0.510501378 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGQIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4288|beta-lactamase_I140K|0.5102492279999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTKGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4289|beta-lactamase_I93S|0.509253333 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRSHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4290|beta-lactamase_T261R|0.509007047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYRTGSQATMDERNRQIAEIGASLIKHW ->4291|beta-lactamase_L223H|0.508920065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAHPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4292|beta-lactamase_S264P|0.508893677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGPQATMDERNRQIAEIGASLIKHW ->4293|beta-lactamase_V72G|0.50858191 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKGLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4294|beta-lactamase_N130T|0.5075449670000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDTTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4295|beta-lactamase_G279N|0.506945866 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEINASLIKHW ->4296|beta-lactamase_V117H|0.505066468 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTHRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4297|beta-lactamase_E119Y|0.505066468 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRYLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4298|beta-lactamase_R220L|0.504987305 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLLSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4299|beta-lactamase_L218Q|0.5047156079999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPQLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4300|beta-lactamase_D231W|0.504538712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIAWKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4301|beta-lactamase_T158C|0.504325655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVCRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4302|beta-lactamase_A246D|0.504212285 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIADLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4303|beta-lactamase_L120S|0.503963067 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRESCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4304|beta-lactamase_L205A|0.503956226 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQAIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4305|beta-lactamase_E145E|0.503816606 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4306|beta-lactamase_V78Q|0.503708962 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAQLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4307|beta-lactamase_V117Y|0.503393286 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTYRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4308|beta-lactamase_A16D|0.502845006 -MSIQHFRVALIPFFADFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4309|beta-lactamase_D161L|0.50213449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLLRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4310|beta-lactamase_N272M|0.501576437 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERMRQIAEIGASLIKHW ->4311|beta-lactamase_R220M|0.501307672 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLMSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4312|beta-lactamase_V117S|0.5007281179999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTSRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4313|beta-lactamase_L100N|0.500179838 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDNVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4314|beta-lactamase_A23W|0.500179838 -MSIQHFRVALIPFFAAFCLPVFWHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4315|beta-lactamase_A230Y|0.499004115 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIYDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4316|beta-lactamase_A34E|0.498854584 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDEEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4317|beta-lactamase_I45N|0.498175342 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYNELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4318|beta-lactamase_W208T|0.497802981 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDTMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4319|beta-lactamase_F17D|0.497629994 -MSIQHFRVALIPFFAADCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4320|beta-lactamase_P65L|0.496884294 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFLMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4321|beta-lactamase_L167D|0.496481636 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEDNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4322|beta-lactamase_G242N|0.496434724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRNIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4323|beta-lactamase_R202F|0.496181597 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASFQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4324|beta-lactamase_L120H|0.495669478 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREHCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4325|beta-lactamase_R241E|0.495558063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSEGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4326|beta-lactamase_G114R|0.494935506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDRMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4327|beta-lactamase_S104Y|0.4945953970000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYYPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4328|beta-lactamase_D174F|0.494398954 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNFERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4329|beta-lactamase_Y95G|0.493269165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHGSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4330|beta-lactamase_L218S|0.493058063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPSLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4331|beta-lactamase_L223Y|0.492993559 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAYPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4332|beta-lactamase_M184S|0.490406577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAASATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4333|beta-lactamase_T187Y|0.490406577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATYLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4334|beta-lactamase_G141W|0.489518188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIWGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4335|beta-lactamase_L218H|0.489244537 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPHLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4336|beta-lactamase_K284P|0.487275225 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIPHW ->4337|beta-lactamase_T69M|0.48714915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSMFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4338|beta-lactamase_P143Y|0.486741605 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGYKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4339|beta-lactamase_S240Y|0.486701534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGYRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4340|beta-lactamase_Y44C|0.486298876 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGCIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4341|beta-lactamase_D48F|0.486271511 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELFLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4342|beta-lactamase_M209F|0.484705835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWFEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4343|beta-lactamase_T69A|0.483830151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSAFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4344|beta-lactamase_A235E|0.483736327 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGEGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4345|beta-lactamase_M115N|0.483348329 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGNTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4346|beta-lactamase_V72F|0.482906577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKFLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4347|beta-lactamase_G114V|0.481797312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDVMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4348|beta-lactamase_M180P|0.481554935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTPPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4349|beta-lactamase_L73L|0.48099346 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4350|beta-lactamase_S51P|0.480633317 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNPGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4351|beta-lactamase_E119L|0.480633317 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRLLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4352|beta-lactamase_D174K|0.479719517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNKERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4353|beta-lactamase_A245F|0.479152668 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIFALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4354|beta-lactamase_R220I|0.479106734 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLISALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4355|beta-lactamase_A40R|0.478898563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGRRVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4356|beta-lactamase_G248N|0.478638595 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALNPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4357|beta-lactamase_L188Q|0.478411855 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTQRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4358|beta-lactamase_L191E|0.477991605 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKELTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4359|beta-lactamase_R220E|0.477794185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLESALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4360|beta-lactamase_W208S|0.476421042 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDSMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4361|beta-lactamase_P224W|0.473956226 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALWAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4362|beta-lactamase_I11E|0.472968149 -MSIQHFRVALEPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4363|beta-lactamase_P20F|0.472814709 -MSIQHFRVALIPFFAAFCLFVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4364|beta-lactamase_K53P|0.472790276 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGPILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4365|beta-lactamase_T69Y|0.471748446 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSYFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4366|beta-lactamase_R220D|0.470905991 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLDSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4367|beta-lactamase_N168F|0.470694889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELFEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4368|beta-lactamase_M209W|0.470345983 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWWEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4369|beta-lactamase_D83I|0.470152473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVIAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4370|beta-lactamase_T158M|0.469774247 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVMRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4371|beta-lactamase_P65Y|0.469356929 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFYMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4372|beta-lactamase_T178N|0.469135076 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDNTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4373|beta-lactamase_S201I|0.468998251 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAIRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4374|beta-lactamase_L219Y|0.46747069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLYRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4375|beta-lactamase_I278T|0.466927297 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAETGASLIKHW ->4376|beta-lactamase_F228D|0.464891527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWDIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4377|beta-lactamase_N168Y|0.464640354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELYEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4378|beta-lactamase_N130A|0.464612011 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDATAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4379|beta-lactamase_V42S|0.464344224 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARSGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4380|beta-lactamase_N272R|0.464344224 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERRRQIAEIGASLIKHW ->4381|beta-lactamase_V78W|0.463181206 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAWLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4382|beta-lactamase_P65F|0.462786366 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFFMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4383|beta-lactamase_L282Y|0.462715999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASYIKHW ->4384|beta-lactamase_M115H|0.461086796 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGHTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4385|beta-lactamase_V78Y|0.458154818 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAYLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4386|beta-lactamase_V31F|0.458079564 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKFKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4387|beta-lactamase_I229T|0.458079564 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFTADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4388|beta-lactamase_E35H|0.458079564 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAHDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4389|beta-lactamase_D161K|0.456796335 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLKRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4390|beta-lactamase_A132C|0.456200166 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTCANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4391|beta-lactamase_D212M|0.456200166 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAMKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4392|beta-lactamase_P143D|0.456200166 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGDKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4393|beta-lactamase_L205T|0.455502355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQTIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4394|beta-lactamase_R202D|0.454570964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASDQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4395|beta-lactamase_L73W|0.453978704 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVWLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4396|beta-lactamase_L47N|0.453978704 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIENDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4397|beta-lactamase_D48W|0.453485154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELWLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4398|beta-lactamase_I256T|0.451833473 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRTVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4399|beta-lactamase_T131Q|0.450561972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNQAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4400|beta-lactamase_L219G|0.450181792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLGRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4401|beta-lactamase_M209G|0.450091878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWGEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4402|beta-lactamase_L218Y|0.448376671 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPYLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4403|beta-lactamase_D161W|0.448056108 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLWRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4404|beta-lactamase_E87K|0.447906577 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQKQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4405|beta-lactamase_I229S|0.447489259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFSADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4406|beta-lactamase_S128G|0.447463849 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4407|beta-lactamase_G239Q|0.445729095 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERQSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4408|beta-lactamase_D161R|0.445022488 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLRRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4409|beta-lactamase_K213D|0.444877844 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADDVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4410|beta-lactamase_L74S|0.444576828 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLSCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4411|beta-lactamase_L79S|0.444144849 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVSSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4412|beta-lactamase_W227A|0.444044185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGAFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4413|beta-lactamase_P20L|0.442208767 -MSIQHFRVALIPFFAAFCLLVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4414|beta-lactamase_A215L|0.442081714 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVLGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4415|beta-lactamase_V31V|0.440873792 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4416|beta-lactamase_K30P|0.438031675 -MSIQHFRVALIPFFAAFCLPVFAHPETLVPVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4417|beta-lactamase_V117E|0.4369654120000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTERELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4418|beta-lactamase_L191N|0.436209939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKNLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4419|beta-lactamase_V31W|0.436209939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKWKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4420|beta-lactamase_A235Y|0.435413419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGYGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4421|beta-lactamase_R220W|0.435221863 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLWSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4422|beta-lactamase_L79T|0.434316859 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVTSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4423|beta-lactamase_W286P|0.433377649 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHP ->4424|beta-lactamase_D212I|0.433343442 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAIKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4425|beta-lactamase_G279Q|0.431767015 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIQASLIKHW ->4426|beta-lactamase_L49D|0.431767015 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDDNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4427|beta-lactamase_L223P|0.429848524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAPPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4428|beta-lactamase_D83Y|0.429387226 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVYAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4429|beta-lactamase_S233C|0.428628821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKCGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4430|beta-lactamase_L192G|0.428191957 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLGTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4431|beta-lactamase_L135W|0.428008219 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANWLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4432|beta-lactamase_C121Q|0.427325068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELQSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4433|beta-lactamase_G236E|0.426825655 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAEERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4434|beta-lactamase_P20I|0.426712285 -MSIQHFRVALIPFFAAFCLIVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4435|beta-lactamase_R241F|0.426336992 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSFGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4436|beta-lactamase_A133V|0.425807281 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAVNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4437|beta-lactamase_A235R|0.424001183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGRGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4438|beta-lactamase_S201D|0.422935897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLADRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4439|beta-lactamase_R220Y|0.422828391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLYSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4440|beta-lactamase_T69L|0.422551808 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSLFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4441|beta-lactamase_N168K|0.422168696 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELKEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4442|beta-lactamase_L120Q|0.421993755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREQCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4443|beta-lactamase_L160D|0.421993755 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRDDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4444|beta-lactamase_N134E|0.421335037 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAELLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4445|beta-lactamase_R220P|0.420739846 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLPSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4446|beta-lactamase_E119F|0.41955044 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRFLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4447|beta-lactamase_A9A|0.419222736 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4448|beta-lactamase_W286E|0.418611229 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHE ->4449|beta-lactamase_F64L|0.416730854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERLPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4450|beta-lactamase_M115G|0.416730854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGGTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4451|beta-lactamase_Y103K|0.4154779220000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEKSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4452|beta-lactamase_L188N|0.414885663 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTNRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4453|beta-lactamase_Y44A|0.414484959 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGAIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4454|beta-lactamase_S104K|0.414427297 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYKPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4455|beta-lactamase_A215W|0.414314904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVWGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4456|beta-lactamase_I140D|0.412220495 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTDGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4457|beta-lactamase_A230F|0.411858884 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIFDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4458|beta-lactamase_T131W|0.410823896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNWAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4459|beta-lactamase_F64Q|0.410823896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERQPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4460|beta-lactamase_D174W|0.410823896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNWERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4461|beta-lactamase_L79Y|0.410308845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVYSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4462|beta-lactamase_A34P|0.409314904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDPEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4463|beta-lactamase_G236Q|0.406980072 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAQERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4464|beta-lactamase_Q204P|0.404172215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQPLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4465|beta-lactamase_V31G|0.402769752 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKGKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4466|beta-lactamase_G114I|0.402447234 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDIMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4467|beta-lactamase_T27Y|0.402447234 -MSIQHFRVALIPFFAAFCLPVFAHPEYLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4468|beta-lactamase_I140R|0.402219517 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTRGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4469|beta-lactamase_M209T|0.401083864 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWTEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4470|beta-lactamase_R162V|0.400352824 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDVWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4471|beta-lactamase_D212F|0.399655014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAFKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4472|beta-lactamase_F14N|0.398171433 -MSIQHFRVALIPFNAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4473|beta-lactamase_N272K|0.397504896 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERKRQIAEIGASLIKHW ->4474|beta-lactamase_M209Q|0.396862793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWQEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4475|beta-lactamase_L192N|0.396862793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLNTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4476|beta-lactamase_T158I|0.3961082970000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVIRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4477|beta-lactamase_G242M|0.395648954 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRMIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4478|beta-lactamase_T179V|0.394684333 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTVMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4479|beta-lactamase_G279E|0.394474208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIEASLIKHW ->4480|beta-lactamase_I275W|0.393759783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQWAEIGASLIKHW ->4481|beta-lactamase_Q203C|0.393759783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRCQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4482|beta-lactamase_A245I|0.392499032 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIIALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4483|beta-lactamase_Y95S|0.390552199 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHSSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4484|beta-lactamase_D212W|0.390139767 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEAWKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4485|beta-lactamase_A235H|0.389687265 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGHGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4486|beta-lactamase_L218E|0.38750001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPELRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4487|beta-lactamase_R59T|0.386696648 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFTPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4488|beta-lactamase_T147F|0.386270534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELFAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4489|beta-lactamase_E87R|0.385425147 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQRQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4490|beta-lactamase_I229N|0.383729486 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFNADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4491|beta-lactamase_I243H|0.383466585 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGHIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4492|beta-lactamase_C75N|0.382900713 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLNGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4493|beta-lactamase_V258N|0.382900713 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVNIYTTGSQATMDERNRQIAEIGASLIKHW ->4494|beta-lactamase_V42H|0.382900713 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARHGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4495|beta-lactamase_A235K|0.382900713 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGKGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4496|beta-lactamase_L218R|0.381142504 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPRLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4497|beta-lactamase_P65M|0.3805737 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFMMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4498|beta-lactamase_L223E|0.380211112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAEPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4499|beta-lactamase_G239T|0.379612989 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERTSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4500|beta-lactamase_W286R|0.378976749 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHR ->4501|beta-lactamase_I229W|0.378828196 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFWADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4502|beta-lactamase_R255F|0.3786513 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSFIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4503|beta-lactamase_A235D|0.378578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGDGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4504|beta-lactamase_T69G|0.378458767 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSGFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4505|beta-lactamase_A235F|0.378458767 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGFGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4506|beta-lactamase_G154I|0.378458767 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMIDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4507|beta-lactamase_L79N|0.377983786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVNSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4508|beta-lactamase_F70E|0.377757047 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTEKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4509|beta-lactamase_L120Y|0.37608191 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREYCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4510|beta-lactamase_F14P|0.375749619 -MSIQHFRVALIPFPAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4511|beta-lactamase_I283P|0.375159314 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLPKHW ->4512|beta-lactamase_S240V|0.374876867 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGVRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4513|beta-lactamase_V214D|0.374812363 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKDAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4514|beta-lactamase_G239D|0.374604193 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERDSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4515|beta-lactamase_Y260S|0.374062754 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVISTTGSQATMDERNRQIAEIGASLIKHW ->4516|beta-lactamase_L218W|0.373381558 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPWLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4517|beta-lactamase_V31N|0.373127453 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKNKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4518|beta-lactamase_P20W|0.373127453 -MSIQHFRVALIPFFAAFCLWVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4519|beta-lactamase_R255G|0.372775616 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSGIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4520|beta-lactamase_F64I|0.3723348420000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERIPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4521|beta-lactamase_W227S|0.371730854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGSFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4522|beta-lactamase_I243D|0.371047703 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGDIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4523|beta-lactamase_H285P|0.369735154 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKPW ->4524|beta-lactamase_C18K|0.368938634 -MSIQHFRVALIPFFAAFKLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4525|beta-lactamase_T126P|0.367543012 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAIPMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4526|beta-lactamase_L74G|0.36661162 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLGCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4527|beta-lactamase_F58D|0.36661162 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESDRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4528|beta-lactamase_L79E|0.36638879 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVESRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4529|beta-lactamase_L160Y|0.366265647 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRYDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4530|beta-lactamase_L282K|0.365653841 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASKIKHW ->4531|beta-lactamase_N134L|0.36480259 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAALLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4532|beta-lactamase_W286K|0.364717563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHK ->4533|beta-lactamase_R241Y|0.364594419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSYGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4534|beta-lactamase_W227H|0.364105756 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGHFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4535|beta-lactamase_Y260W|0.363897586 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIWTTGSQATMDERNRQIAEIGASLIKHW ->4536|beta-lactamase_L218K|0.363557477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPKLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4537|beta-lactamase_S104D|0.363354193 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYDPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4538|beta-lactamase_I93P|0.362087578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRPHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4539|beta-lactamase_A215D|0.361810018 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVDGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4540|beta-lactamase_N168P|0.361620416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELPEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4541|beta-lactamase_W286D|0.361521706 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHD ->4542|beta-lactamase_Y260A|0.360384099 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIATTGSQATMDERNRQIAEIGASLIKHW ->4543|beta-lactamase_A246R|0.360370416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIARLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4544|beta-lactamase_G236H|0.358467563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAHERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4545|beta-lactamase_N134W|0.35624609999999995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAWLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4546|beta-lactamase_V257E|0.355568814 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIEVIYTTGSQATMDERNRQIAEIGASLIKHW ->4547|beta-lactamase_M184H|0.354977531 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAHATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4548|beta-lactamase_A133P|0.354296335 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAPNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4549|beta-lactamase_W208V|0.354104779 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDVMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4550|beta-lactamase_N272L|0.353580932 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERLRQIAEIGASLIKHW ->4551|beta-lactamase_E35L|0.353580932 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDALDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4552|beta-lactamase_S57P|0.353301417 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILEPFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4553|beta-lactamase_L74Q|0.353251573 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLQCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4554|beta-lactamase_V157P|0.352829369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHPTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4555|beta-lactamase_I275A|0.352495123 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQAAEIGASLIKHW ->4556|beta-lactamase_G236I|0.351529525 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAIERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4557|beta-lactamase_L136S|0.350788712 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLSLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4558|beta-lactamase_A124Q|0.350323505 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAQITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4559|beta-lactamase_V258F|0.350323505 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVFIYTTGSQATMDERNRQIAEIGASLIKHW ->4560|beta-lactamase_D83L|0.349923778 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVLAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4561|beta-lactamase_F70K|0.349528939 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTKKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4562|beta-lactamase_I243S|0.349397 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGSIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4563|beta-lactamase_L205Q|0.348406968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQQIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4564|beta-lactamase_L205E|0.3470651 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQEIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4565|beta-lactamase_R255N|0.346599892 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSNIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4566|beta-lactamase_L167K|0.346250987 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEKNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4567|beta-lactamase_G242T|0.346203098 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRTIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4568|beta-lactamase_S240L|0.345495514 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGLRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4569|beta-lactamase_G239M|0.343871198 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERMSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4570|beta-lactamase_I256G|0.343807672 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRGVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4571|beta-lactamase_I243N|0.343460721 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGNIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4572|beta-lactamase_R59D|0.343392308 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFDPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4573|beta-lactamase_P65E|0.34293589700000005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFEMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4574|beta-lactamase_L282H|0.342623153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASHIKHW ->4575|beta-lactamase_M1T|0.34217847 -TSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4576|beta-lactamase_L160K|0.341488477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRKDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4577|beta-lactamase_G239R|0.34115618600000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERRSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4578|beta-lactamase_I229H|0.339957985 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFHADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4579|beta-lactamase_L135G|0.339693129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANGLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4580|beta-lactamase_F64C|0.33964230799999995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERCPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4581|beta-lactamase_G239K|0.33961885299999994 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERKSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4582|beta-lactamase_M209I|0.338688438 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWIEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4583|beta-lactamase_G242H|0.337591878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRHIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4584|beta-lactamase_S104I|0.33752444299999995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYIPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4585|beta-lactamase_A15D|0.33708855600000004 -MSIQHFRVALIPFFDAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4586|beta-lactamase_G236M|0.335989064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAMERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4587|beta-lactamase_G239F|0.335192543 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERFSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4588|beta-lactamase_D212L|0.334785975 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEALKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4589|beta-lactamase_I125F|0.334034412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAFTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4590|beta-lactamase_V101P|0.334034412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLPEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4591|beta-lactamase_M209S|0.333206616 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWSEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4592|beta-lactamase_W227C|0.331001769 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGCFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4593|beta-lactamase_V257W|0.330915764 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIWVIYTTGSQATMDERNRQIAEIGASLIKHW ->4594|beta-lactamase_F14K|0.330915764 -MSIQHFRVALIPFKAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4595|beta-lactamase_S233W|0.330493559 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKWGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4596|beta-lactamase_S104P|0.330459353 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4597|beta-lactamase_A34R|0.329784998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDREDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4598|beta-lactamase_A230T|0.329093051 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFITDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4599|beta-lactamase_G248C|0.328467563 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALCPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4600|beta-lactamase_V78N|0.32747069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGANLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4601|beta-lactamase_T178L|0.327367093 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDLTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4602|beta-lactamase_R255Y|0.327053372 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSYIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4603|beta-lactamase_A123D|0.325890354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSDAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4604|beta-lactamase_R241W|0.325890354 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSWGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4605|beta-lactamase_E119W|0.324261151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRWLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4606|beta-lactamase_F13R|0.323831128 -MSIQHFRVALIPRFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4607|beta-lactamase_W227T|0.322889963 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGTFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4608|beta-lactamase_T27W|0.322758024 -MSIQHFRVALIPFFAAFCLPVFAHPEWLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4609|beta-lactamase_D207P|0.322460917 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIPWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4610|beta-lactamase_Y260Q|0.322399345 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIQTTGSQATMDERNRQIAEIGASLIKHW ->4611|beta-lactamase_R189P|0.321365334 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLPKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4612|beta-lactamase_L247S|0.319592465 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAASGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4613|beta-lactamase_I229Q|0.318813536 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFQADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4614|beta-lactamase_P181M|0.318603411 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMMAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4615|beta-lactamase_T178Y|0.318389376 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDYTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4616|beta-lactamase_M66E|0.318246687 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPEMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4617|beta-lactamase_M67Y|0.318138204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMYSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4618|beta-lactamase_W227V|0.317270338 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGVFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4619|beta-lactamase_A34D|0.316677101 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDDEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4620|beta-lactamase_P143W|0.316031089 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGWKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4621|beta-lactamase_L146H|0.315709548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEHTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4622|beta-lactamase_G76H|0.315239455 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCHAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4623|beta-lactamase_W227G|0.314825068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGGFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4624|beta-lactamase_L192E|0.313913223 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLETGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4625|beta-lactamase_L79G|0.312558649 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVGSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4626|beta-lactamase_D48P|0.312442348 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELPLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4627|beta-lactamase_D177S|0.311147391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERSTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4628|beta-lactamase_L136G|0.311009588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLGLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4629|beta-lactamase_L120G|0.308940588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREGCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4630|beta-lactamase_C121N|0.308623935 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELNSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4631|beta-lactamase_S240R|0.307267406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGRRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4632|beta-lactamase_L160E|0.306702512 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTREDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4633|beta-lactamase_I278A|0.305045944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEAGASLIKHW ->4634|beta-lactamase_Q203P|0.304961894 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRPQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4635|beta-lactamase_Y44T|0.304629603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGTIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4636|beta-lactamase_F13E|0.304237695 -MSIQHFRVALIPEFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4637|beta-lactamase_I125Q|0.303085428 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAQTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4638|beta-lactamase_G239Y|0.302561581 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERYSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4639|beta-lactamase_G142M|0.301457203 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGMPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4640|beta-lactamase_I45D|0.30080532600000004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYDELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4641|beta-lactamase_Y44G|0.30017983800000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGGIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4642|beta-lactamase_G248W|0.299384294 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALWPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4643|beta-lactamase_S201E|0.299313927 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLAERQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4644|beta-lactamase_G142Y|0.29913019 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGYPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4645|beta-lactamase_I11D|0.297384685 -MSIQHFRVALDPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4646|beta-lactamase_R162W|0.296803176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDWWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4647|beta-lactamase_I244G|0.296456226 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIGAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4648|beta-lactamase_G216G|0.296109127 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4649|beta-lactamase_T131K|0.296027179 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNKAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4650|beta-lactamase_T178D|0.295853215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDDTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4651|beta-lactamase_T178K|0.295808258 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDKTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4652|beta-lactamase_D83P|0.295440784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVPAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4653|beta-lactamase_I229G|0.294343247 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFGADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4654|beta-lactamase_L146N|0.293593638 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKENTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4655|beta-lactamase_I229K|0.29356725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFKADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4656|beta-lactamase_P65R|0.293551613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFRMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4657|beta-lactamase_G242Q|0.29345388 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRQIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4658|beta-lactamase_G248R|0.293123544 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALRPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4659|beta-lactamase_T178F|0.292685702 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDFTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4660|beta-lactamase_L150E|0.292516624 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFEHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4661|beta-lactamase_D155S|0.29214915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGSHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4662|beta-lactamase_I93D|0.292039689 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRDHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4663|beta-lactamase_T178E|0.290916742 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDETMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4664|beta-lactamase_E87P|0.290598133 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQPQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4665|beta-lactamase_I244Y|0.290311777 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIYAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4666|beta-lactamase_M66N|0.290089924 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPNMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4667|beta-lactamase_T69N|0.289935506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSNFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4668|beta-lactamase_E277P|0.28892690600000004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAPIGASLIKHW ->4669|beta-lactamase_Y95Q|0.287581128 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHQSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4670|beta-lactamase_R241D|0.287176515 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSDGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4671|beta-lactamase_L205Y|0.286253919 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQYIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4672|beta-lactamase_L120N|0.28516811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRENCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4673|beta-lactamase_L160W|0.28516811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRWDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4674|beta-lactamase_D155Q|0.28516811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGQHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4675|beta-lactamase_T116W|0.28516811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMWVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4676|beta-lactamase_L100D|0.28516811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDDVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4677|beta-lactamase_V78K|0.284373544 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAKLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4678|beta-lactamase_V117G|0.284340315 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTGRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4679|beta-lactamase_L55P|0.282760956 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKIPESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4680|beta-lactamase_S104Q|0.28179829 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYQPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4681|beta-lactamase_E35Y|0.281548094 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAYDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4682|beta-lactamase_L167R|0.281276398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPERNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4683|beta-lactamase_G248K|0.28125880600000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALKPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4684|beta-lactamase_G236V|0.281193325 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAVERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4685|beta-lactamase_T107F|0.28072616300000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVFEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4686|beta-lactamase_E35F|0.28028148 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAFDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4687|beta-lactamase_D83W|0.280024443 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVWAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4688|beta-lactamase_T178R|0.279375498 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDRTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4689|beta-lactamase_T131R|0.27818707 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNRAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4690|beta-lactamase_T69E|0.27818707 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSEFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4691|beta-lactamase_A132T|0.277929056 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTTANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4692|beta-lactamase_C75D|0.277650518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLDGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4693|beta-lactamase_L167Y|0.277349502 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEYNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4694|beta-lactamase_W227I|0.277190197 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGIFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4695|beta-lactamase_I278W|0.276669283 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEWGASLIKHW ->4696|beta-lactamase_T178H|0.276488477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDHTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4697|beta-lactamase_L282W|0.276100479 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASWIKHW ->4698|beta-lactamase_D83F|0.275948016 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVFAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4699|beta-lactamase_R162I|0.27430904 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDIWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4700|beta-lactamase_A133N|0.270611816 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTANNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4701|beta-lactamase_I244N|0.270026398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGINAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4702|beta-lactamase_S104F|0.268879017 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYFPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4703|beta-lactamase_S233L|0.2679789 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKLGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4704|beta-lactamase_R59I|0.265621589 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFIPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4705|beta-lactamase_A185L|0.265046921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMLTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4706|beta-lactamase_D177A|0.264942348 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERATTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4707|beta-lactamase_F70R|0.264088165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTRKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4708|beta-lactamase_M1F|0.263449971 -FSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4709|beta-lactamase_A230Q|0.263228118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIQDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4710|beta-lactamase_L247E|0.262829369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAEGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4711|beta-lactamase_V72Q|0.262614357 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKQLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4712|beta-lactamase_W286V|0.26236416100000004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHV ->4713|beta-lactamase_A123K|0.260734959 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSKAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4714|beta-lactamase_W286G|0.260734959 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHG ->4715|beta-lactamase_I229E|0.258924951 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFEADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4716|beta-lactamase_L247Q|0.257522488 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAQGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4717|beta-lactamase_E119V|0.257497078 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRVLCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4718|beta-lactamase_M115W|0.253893677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGWTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4719|beta-lactamase_N272Y|0.253893677 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERYRQIAEIGASLIKHW ->4720|beta-lactamase_G248D|0.253578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALDPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4721|beta-lactamase_I93G|0.253086405 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRGHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4722|beta-lactamase_G142P|0.249628626 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGPPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4723|beta-lactamase_L74N|0.248518384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLNCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4724|beta-lactamase_M184G|0.24686768 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAGATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4725|beta-lactamase_L191G|0.246649736 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKGLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4726|beta-lactamase_A230R|0.246161073 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIRDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4727|beta-lactamase_F14E|0.246075068 -MSIQHFRVALIPFEAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4728|beta-lactamase_L146E|0.245907946 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEETAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4729|beta-lactamase_N272F|0.245072332 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERFRQIAEIGASLIKHW ->4730|beta-lactamase_A15R|0.245058649 -MSIQHFRVALIPFFRAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4731|beta-lactamase_T262Q|0.244445866 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTQGSQATMDERNRQIAEIGASLIKHW ->4732|beta-lactamase_D177E|0.244321746 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERETTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4733|beta-lactamase_D155C|0.243282848 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGCHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4734|beta-lactamase_S240P|0.242455053 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGPRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4735|beta-lactamase_M67K|0.242136444 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMKSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4736|beta-lactamase_G234Y|0.240911855 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSYAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4737|beta-lactamase_I256E|0.240744732 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSREVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4738|beta-lactamase_I45W|0.240060604 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYWELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4739|beta-lactamase_G142V|0.239293403 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGVPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4740|beta-lactamase_L223D|0.23887413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSADPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4741|beta-lactamase_W208G|0.238047312 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDGMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4742|beta-lactamase_G236F|0.237912441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAFERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4743|beta-lactamase_A133F|0.237878235 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAFNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4744|beta-lactamase_T131I|0.237387617 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNIAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4745|beta-lactamase_N130L|0.237387617 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDLTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4746|beta-lactamase_L74K|0.236301808 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLKCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4747|beta-lactamase_F64H|0.236301808 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERHPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4748|beta-lactamase_C121E|0.234981441 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELESAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4749|beta-lactamase_S233Y|0.233650323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKYGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4750|beta-lactamase_I229R|0.233372762 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFRADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4751|beta-lactamase_M184N|0.233247664 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAANATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4752|beta-lactamase_L146S|0.23304438 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKESTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4753|beta-lactamase_W286S|0.231559822 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHS ->4754|beta-lactamase_L79W|0.231459158 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVWSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4755|beta-lactamase_V117W|0.230437852 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTWRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4756|beta-lactamase_V117R|0.227916351 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTRRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4757|beta-lactamase_T107Y|0.227416937 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVYEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4758|beta-lactamase_E164H|0.226528548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWHPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4759|beta-lactamase_I275H|0.225978313 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQHAEIGASLIKHW ->4760|beta-lactamase_F64T|0.22567925100000005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERTPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4761|beta-lactamase_T187R|0.225480854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATRLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4762|beta-lactamase_V117K|0.225442738 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTKRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4763|beta-lactamase_P65W|0.223736327 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFWMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4764|beta-lactamase_V78G|0.223549658 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAGLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4765|beta-lactamase_V257N|0.22327112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRINVIYTTGSQATMDERNRQIAEIGASLIKHW ->4766|beta-lactamase_L167W|0.221564709 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPEWNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4767|beta-lactamase_Y95N|0.220444693 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHNSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4768|beta-lactamase_G76Q|0.220012715 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCQAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4769|beta-lactamase_G142F|0.220012715 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGFPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4770|beta-lactamase_I256S|0.218233004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRSVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4771|beta-lactamase_I259S|0.216904818 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVSYTTGSQATMDERNRQIAEIGASLIKHW ->4772|beta-lactamase_R59V|0.216755287 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFVPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4773|beta-lactamase_G239E|0.216702512 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERESRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4774|beta-lactamase_M115P|0.215726163 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGPTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4775|beta-lactamase_S104W|0.215359666 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYWPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4776|beta-lactamase_F64A|0.214518188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERAPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4777|beta-lactamase_T69Q|0.212566468 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSQFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4778|beta-lactamase_S233Q|0.21132624100000005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKQGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4779|beta-lactamase_S128T|0.209459548 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMTDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4780|beta-lactamase_G85P|0.206877453 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAPQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4781|beta-lactamase_T158N|0.20651682 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVNRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4782|beta-lactamase_C18R|0.206351652 -MSIQHFRVALIPFFAAFRLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4783|beta-lactamase_L137K|0.206230463 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLKTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4784|beta-lactamase_M209V|0.205205248 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWVEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4785|beta-lactamase_T107W|0.205205248 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVWEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4786|beta-lactamase_I229D|0.204977531 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFDADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4787|beta-lactamase_T179I|0.204666742 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTIMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4788|beta-lactamase_L79H|0.204564122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVHSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4789|beta-lactamase_V42Q|0.204249423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARQGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4790|beta-lactamase_M115D|0.203724599 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGDTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4791|beta-lactamase_G236L|0.203301417 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGALERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4792|beta-lactamase_V42G|0.203274052 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARGGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4793|beta-lactamase_L47D|0.203072723 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEDDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4794|beta-lactamase_G43T|0.202587969 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVTYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4795|beta-lactamase_W286T|0.202022097 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHT ->4796|beta-lactamase_S240K|0.201923387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGKRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4797|beta-lactamase_S233N|0.201737695 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKNGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4798|beta-lactamase_S68C|0.201063341 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMCTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4799|beta-lactamase_M1W|0.201009588 -WSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4800|beta-lactamase_L192K|0.199652082 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLKTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4801|beta-lactamase_A123R|0.197646609 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSRAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4802|beta-lactamase_G236W|0.196970299 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAWERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4803|beta-lactamase_A245W|0.194658923 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIWALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4804|beta-lactamase_M127P|0.19429438 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITPSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4805|beta-lactamase_M67R|0.193995319 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMRSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4806|beta-lactamase_A245Y|0.19391811 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIYALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4807|beta-lactamase_L137D|0.193543794 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLDTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4808|beta-lactamase_G248Q|0.193019947 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALQPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4809|beta-lactamase_Y95R|0.19214524 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHRSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4810|beta-lactamase_Y44E|0.191658532 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGEIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4811|beta-lactamase_K32P|0.19134481 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVPDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4812|beta-lactamase_G142L|0.190150518 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGLPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4813|beta-lactamase_V31H|0.189656968 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKHKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4814|beta-lactamase_G248F|0.187435506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALFPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4815|beta-lactamase_E164D|0.187435506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWDPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4816|beta-lactamase_N272W|0.187435506 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERWRQIAEIGASLIKHW ->4817|beta-lactamase_G239W|0.184704857 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERWSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4818|beta-lactamase_T158H|0.183881949 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVHRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4819|beta-lactamase_L282D|0.181434724 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASDIKHW ->4820|beta-lactamase_Y260H|0.180616703 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIHTTGSQATMDERNRQIAEIGASLIKHW ->4821|beta-lactamase_S240I|0.179447821 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGIRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4822|beta-lactamase_S233F|0.1792289 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKFGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4823|beta-lactamase_L188E|0.178314122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTERKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4824|beta-lactamase_D177Y|0.178273075 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERYTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4825|beta-lactamase_V258Y|0.17812745300000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVYIYTTGSQATMDERNRQIAEIGASLIKHW ->4826|beta-lactamase_A235W|0.177325068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGWGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4827|beta-lactamase_E164K|0.17681295 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWKPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4828|beta-lactamase_Y95E|0.176049658 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHESQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4829|beta-lactamase_G236Y|0.175517015 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAYERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4830|beta-lactamase_W208R|0.174896413 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDRMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4831|beta-lactamase_I283D|0.17459441899999995 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLDKHW ->4832|beta-lactamase_V257Q|0.17454750800000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIQVIYTTGSQATMDERNRQIAEIGASLIKHW ->4833|beta-lactamase_S233H|0.174108688 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKHGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4834|beta-lactamase_M1C|0.173955248 -CSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4835|beta-lactamase_M153P|0.172004505 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNPGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4836|beta-lactamase_A280P|0.171587187 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGPSLIKHW ->4837|beta-lactamase_L205S|0.17156470899999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQSIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4838|beta-lactamase_G242V|0.170868853 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRVIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4839|beta-lactamase_G234Q|0.170638204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSQAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4840|beta-lactamase_I256W|0.169665764 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRWVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4841|beta-lactamase_D177F|0.169665764 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERFTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4842|beta-lactamase_N272P|0.169432183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERPRQIAEIGASLIKHW ->4843|beta-lactamase_S233R|0.168472449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKRGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4844|beta-lactamase_L150D|0.168397195 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFDHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4845|beta-lactamase_T187K|0.16815775 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATKLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4846|beta-lactamase_T158Q|0.16758406 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVQRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4847|beta-lactamase_V106P|0.167268384 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPPTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4848|beta-lactamase_T179M|0.16693707 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTMMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4849|beta-lactamase_M1Y|0.165717367 -YSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4850|beta-lactamase_A77P|0.165514083 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGPVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4851|beta-lactamase_V258D|0.165495514 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVDIYTTGSQATMDERNRQIAEIGASLIKHW ->4852|beta-lactamase_D177H|0.165192543 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERHTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4853|beta-lactamase_T131D|0.164166351 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNDAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4854|beta-lactamase_M1N|0.163979681 -NSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4855|beta-lactamase_P65D|0.16384481 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFDMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4856|beta-lactamase_T107D|0.163002355 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVDEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4857|beta-lactamase_L136Q|0.162564513 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLQLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4858|beta-lactamase_T158L|0.161187461 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVLRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4859|beta-lactamase_V72Y|0.159512324 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKYLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4860|beta-lactamase_N130V|0.158867289 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDVTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4861|beta-lactamase_D155A|0.15883112800000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGAHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4862|beta-lactamase_S80P|0.158318032 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLPRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4863|beta-lactamase_G239L|0.158267211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERLSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4864|beta-lactamase_M1Q|0.158115725 -QSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4865|beta-lactamase_M184K|0.157029916 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAKATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4866|beta-lactamase_D177I|0.156894068 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERITTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4867|beta-lactamase_D155I|0.156572527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGIHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4868|beta-lactamase_F64S|0.156338946 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERSPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4869|beta-lactamase_M66P|0.155484763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPPMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4870|beta-lactamase_A276P|0.155157359 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIPEIGASLIKHW ->4871|beta-lactamase_M1K|0.154858297 -KSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4872|beta-lactamase_R162P|0.153229095 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDPWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4873|beta-lactamase_E35W|0.152941761 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAWDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4874|beta-lactamase_R202P|0.152649541 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASPQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4875|beta-lactamase_F70D|0.151896022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTDKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4876|beta-lactamase_D129E|0.151620416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSENTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4877|beta-lactamase_I244E|0.1508151 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIEAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4878|beta-lactamase_T262P|0.15078578 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTPGSQATMDERNRQIAEIGASLIKHW ->4879|beta-lactamase_I275Q|0.150673387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQQAEIGASLIKHW ->4880|beta-lactamase_S104E|0.149755678 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYEPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4881|beta-lactamase_G76N|0.149428274 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCNAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4882|beta-lactamase_T179G|0.149120416 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTGMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4883|beta-lactamase_G248M|0.148342465 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALMPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4884|beta-lactamase_Y95K|0.148027766 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHKSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4885|beta-lactamase_G234N|0.147618266 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSNAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4886|beta-lactamase_V257H|0.147339728 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIHVIYTTGSQATMDERNRQIAEIGASLIKHW ->4887|beta-lactamase_N130E|0.147193129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDETAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4888|beta-lactamase_W227L|0.146190393 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGLFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4889|beta-lactamase_A230H|0.145550244 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIHDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4890|beta-lactamase_T261D|0.145550244 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYDTGSQATMDERNRQIAEIGASLIKHW ->4891|beta-lactamase_V257G|0.145251183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIGVIYTTGSQATMDERNRQIAEIGASLIKHW ->4892|beta-lactamase_L247H|0.145195475 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAHGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4893|beta-lactamase_E119I|0.144677492 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRILCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4894|beta-lactamase_D177V|0.143445084 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERVTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4895|beta-lactamase_L136N|0.143370807 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLNLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4896|beta-lactamase_A133H|0.143360057 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAHNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4897|beta-lactamase_W286C|0.143114748 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHC ->4898|beta-lactamase_G248Y|0.142641722 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALYPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4899|beta-lactamase_F64K|0.142328 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERKPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4900|beta-lactamase_T193P|0.142010369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLPGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4901|beta-lactamase_G236R|0.141378039 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGARERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4902|beta-lactamase_C121F|0.14101252 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELFSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4903|beta-lactamase_S240W|0.140145631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGWRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4904|beta-lactamase_M1E|0.140145631 -ESIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4905|beta-lactamase_D177Q|0.139889572 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERQTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4906|beta-lactamase_V72N|0.138569204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKNLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4907|beta-lactamase_L191K|0.13724883699999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKKLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4908|beta-lactamase_R91P|0.13715696800000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGPRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4909|beta-lactamase_V72E|0.137088556 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKELLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4910|beta-lactamase_I275S|0.136953685 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQSAEIGASLIKHW ->4911|beta-lactamase_G236K|0.13608484199999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAKERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4912|beta-lactamase_D177W|0.135694889 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERWTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4913|beta-lactamase_Y95D|0.135395827 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHDSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4914|beta-lactamase_G234F|0.135311777 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSFAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4915|beta-lactamase_M66W|0.135311777 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPWMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4916|beta-lactamase_G242E|0.13439309 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSREIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4917|beta-lactamase_T158Y|0.134127258 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVYRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4918|beta-lactamase_I125G|0.133052199 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAGTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4919|beta-lactamase_G248T|0.132082692 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALTPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4920|beta-lactamase_G279R|0.131861816 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIRASLIKHW ->4921|beta-lactamase_I244Q|0.131730854 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIQAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4922|beta-lactamase_I206P|0.131588165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLPDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4923|beta-lactamase_I256Q|0.131051613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRQVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4924|beta-lactamase_I259G|0.130726163 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVGYTTGSQATMDERNRQIAEIGASLIKHW ->4925|beta-lactamase_M1D|0.130425147 -DSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4926|beta-lactamase_M67W|0.12994625699999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMWSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4927|beta-lactamase_G142W|0.12994625699999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGWPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4928|beta-lactamase_L136E|0.12984266 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLELTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4929|beta-lactamase_M1S|0.129172215 -SSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4930|beta-lactamase_G234L|0.128795944 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSLAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4931|beta-lactamase_D155T|0.127710135 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGTHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4932|beta-lactamase_G76E|0.127292817 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCEAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4933|beta-lactamase_S104L|0.126773857 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYLPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4934|beta-lactamase_I125E|0.126650713 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAETMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4935|beta-lactamase_S233K|0.125821941 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKKGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4936|beta-lactamase_L247G|0.124921824 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAGGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4937|beta-lactamase_D177T|0.123751964 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERTTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4938|beta-lactamase_G239P|0.123549658 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERPSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4939|beta-lactamase_G142I|0.122280111 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGIPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4940|beta-lactamase_M184E|0.121465999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAEATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4941|beta-lactamase_Y260N|0.120244341 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVINTTGSQATMDERNRQIAEIGASLIKHW ->4942|beta-lactamase_I45K|0.119520143 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYKELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4943|beta-lactamase_P181N|0.119207398 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMNAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4944|beta-lactamase_I259N|0.119022684 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTGSQATMDERNRQIAEIGASLIKHW ->4945|beta-lactamase_T107Q|0.119022684 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVQEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4946|beta-lactamase_V31Y|0.118448016 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKYKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4947|beta-lactamase_A124E|0.118076632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAEITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4948|beta-lactamase_M1A|0.11697714 -ASIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4949|beta-lactamase_E61P|0.116637031 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPPERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4950|beta-lactamase_F64R|0.116357516 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERRPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4951|beta-lactamase_T158D|0.113873153 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVDRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4952|beta-lactamase_D155V|0.113509588 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGVHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4953|beta-lactamase_G234E|0.112822527 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSEAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4954|beta-lactamase_G239V|0.112589924 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERVSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4955|beta-lactamase_L282R|0.112370025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASRIKHW ->4956|beta-lactamase_I256N|0.111421042 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRNVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4957|beta-lactamase_K71R|0.111421042 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFRVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4958|beta-lactamase_V82P|0.111116116 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRPDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4959|beta-lactamase_V31P|0.11108191 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKPKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4960|beta-lactamase_W208K|0.110878626 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDKMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4961|beta-lactamase_L120E|0.110646022 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREECSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4962|beta-lactamase_D177M|0.10849786 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERMTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4963|beta-lactamase_D155H|0.108027766 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGHHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4964|beta-lactamase_N130I|0.108027766 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDITAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4965|beta-lactamase_L74P|0.107802004 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLPCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4966|beta-lactamase_L150P|0.107327023 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFPHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4967|beta-lactamase_T107E|0.107155014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVEEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4968|beta-lactamase_Y44S|0.106949775 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGSIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4969|beta-lactamase_M1R|0.106949775 -RSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4970|beta-lactamase_T107R|0.105991996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVREKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4971|beta-lactamase_L160R|0.105839533 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRRDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4972|beta-lactamase_I275G|0.105612793 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQGAEIGASLIKHW ->4973|beta-lactamase_L73K|0.104739064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVKLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4974|beta-lactamase_D155P|0.104739064 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGPHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4975|beta-lactamase_C75E|0.103664982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLEGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4976|beta-lactamase_D177L|0.103664982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERLTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4977|beta-lactamase_R255W|0.103664982 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSWIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4978|beta-lactamase_Y44D|0.103385467 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGDIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4979|beta-lactamase_K232A|0.103076632 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADASGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4980|beta-lactamase_D177R|0.102647586 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERRTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4981|beta-lactamase_T179L|0.102303567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTLMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4982|beta-lactamase_N130M|0.101919478 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDMTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4983|beta-lactamase_A245N|0.101793403 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIINALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4984|beta-lactamase_T107H|0.100980268 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVHEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4985|beta-lactamase_A230N|0.100561972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFINDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4986|beta-lactamase_D155F|0.100561972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGFHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4987|beta-lactamase_D155M|0.100561972 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGMHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4988|beta-lactamase_V31D|0.099727336 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKDKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4989|beta-lactamase_T178W|0.099264083 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDWTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4990|beta-lactamase_G248V|0.099010956 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALVPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4991|beta-lactamase_G76D|0.098922996 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCDAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4992|beta-lactamase_D155G|0.098770534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGGHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4993|beta-lactamase_I278Y|0.098587774 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEYGASLIKHW ->4994|beta-lactamase_T107P|0.09820173 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVPEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4995|beta-lactamase_S233E|0.097985741 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKEGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4996|beta-lactamase_L135D|0.097923192 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANDLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4997|beta-lactamase_L205N|0.097846961 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQNIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4998|beta-lactamase_C75Q|0.097220495 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLQGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->4999|beta-lactamase_I243G|0.097115921 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGGIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5000|beta-lactamase_L137R|0.096352629 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLRTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5001|beta-lactamase_A245Q|0.095662637 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIQALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5002|beta-lactamase_W227N|0.095626476 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGNFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5003|beta-lactamase_E164R|0.095451534 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWRPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5004|beta-lactamase_I140P|0.09484657 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTPGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5005|beta-lactamase_D129C|0.094541644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSCNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5006|beta-lactamase_I244H|0.092368071 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIHAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5007|beta-lactamase_A124D|0.09151291 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSADITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5008|beta-lactamase_K232T|0.09127933 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADTSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5009|beta-lactamase_D129S|0.090491605 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSSNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5010|beta-lactamase_M184W|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAWATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5011|beta-lactamase_T69F|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSFFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5012|beta-lactamase_V31Q|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKQKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5013|beta-lactamase_D177P|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERPTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5014|beta-lactamase_E164P|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWPPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5015|beta-lactamase_D155L|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGLHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5016|beta-lactamase_D155Y|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGYHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5017|beta-lactamase_L192D|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLDTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5018|beta-lactamase_L192R|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLRTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5019|beta-lactamase_F228P|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWPIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5020|beta-lactamase_E35P|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAPDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5021|beta-lactamase_D33P|0.08970290300000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKPAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5022|beta-lactamase_C18I|0.08970290300000001 -MSIQHFRVALIPFFAAFILPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5023|beta-lactamase_F13D|0.08970290300000001 -MSIQHFRVALIPDFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5024|beta-lactamase_F14R|0.08970290300000001 -MSIQHFRVALIPFRAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5025|beta-lactamase_M1H|0.08970290300000001 -HSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5026|beta-lactamase_L136H|0.087506851 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLHLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5027|beta-lactamase_G248E|0.08743062 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALEPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5028|beta-lactamase_T107K|0.08743062 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVKEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5029|beta-lactamase_V78D|0.084691175 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGADLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5030|beta-lactamase_I259Q|0.084559236 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVQYTTGSQATMDERNRQIAEIGASLIKHW ->5031|beta-lactamase_A230E|0.08427287900000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIEDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5032|beta-lactamase_L247R|0.084171237 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAARGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5033|beta-lactamase_V31E|0.08411846199999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKEKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5034|beta-lactamase_D177K|0.08411846199999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERKTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5035|beta-lactamase_K232N|0.08366986900000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADNSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5036|beta-lactamase_K232C|0.083397195 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADCSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5037|beta-lactamase_Y44Q|0.082185311 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGQIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5038|beta-lactamase_V31R|0.08172499 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKRKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5039|beta-lactamase_L79R|0.081326241 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVRSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5040|beta-lactamase_N130P|0.080394849 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDPTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5041|beta-lactamase_I275E|0.079306108 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQEAEIGASLIKHW ->5042|beta-lactamase_A230K|0.078843833 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIKDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5043|beta-lactamase_G242D|0.07820466200000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRDIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5044|beta-lactamase_G43F|0.07820466200000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVFYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5045|beta-lactamase_I275N|0.077784412 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQNAEIGASLIKHW ->5046|beta-lactamase_A185Q|0.077735545 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMQTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5047|beta-lactamase_V31K|0.07748632700000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKKKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5048|beta-lactamase_W227Q|0.07748632700000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGQFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5049|beta-lactamase_F149P|0.077092465 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAPLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5050|beta-lactamase_E56P|0.076376085 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILPSFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5051|beta-lactamase_A185N|0.075740823 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMNTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5052|beta-lactamase_L205H|0.075740823 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQHIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5053|beta-lactamase_F64E|0.075740823 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEEREPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5054|beta-lactamase_L188K|0.073854584 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTKRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5055|beta-lactamase_R255D|0.073793012 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSDIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5056|beta-lactamase_D129N|0.07358191 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSNNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5057|beta-lactamase_C75P|0.07341381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLPGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5058|beta-lactamase_M209E|0.07341381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWEEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5059|beta-lactamase_D161P|0.07341381 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLPRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5060|beta-lactamase_L74H|0.07245603 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLHCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5061|beta-lactamase_G239I|0.072160878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERISRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5062|beta-lactamase_I125D|0.071933161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAADTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5063|beta-lactamase_L79D|0.071933161 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVDSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5064|beta-lactamase_W227E|0.07160477900000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGEFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5065|beta-lactamase_T69T|0.071564848 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5066|beta-lactamase_P181H|0.071262715 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMHAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5067|beta-lactamase_G279D|0.070156382 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIDASLIKHW ->5068|beta-lactamase_G279K|0.070156382 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIKASLIKHW ->5069|beta-lactamase_L247P|0.068759783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAPGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5070|beta-lactamase_M209Y|0.067984763 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWYEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5071|beta-lactamase_K232V|0.06736416099999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADVSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5072|beta-lactamase_R81P|0.066974208 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSPVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5073|beta-lactamase_M1P|0.065269752 -PSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5074|beta-lactamase_I256D|0.064482027 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRDVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5075|beta-lactamase_K232S|0.064308063 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADSSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5076|beta-lactamase_V42E|0.063446061 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGAREGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5077|beta-lactamase_S233I|0.06339035400000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKIGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5078|beta-lactamase_N130H|0.062742387 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDHTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5079|beta-lactamase_F14D|0.06177972 -MSIQHFRVALIPFDAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5080|beta-lactamase_W227R|0.061057477 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGRFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5081|beta-lactamase_L191D|0.060383122 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKDLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5082|beta-lactamase_V257D|0.059631558 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIDVIYTTGSQATMDERNRQIAEIGASLIKHW ->5083|beta-lactamase_G76P|0.05712569400000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCPAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5084|beta-lactamase_M209N|0.05712569400000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWNEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5085|beta-lactamase_I278S|0.05712569400000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAESGASLIKHW ->5086|beta-lactamase_L188D|0.054519165 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTDRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5087|beta-lactamase_V117D|0.054163419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTDRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5088|beta-lactamase_T178P|0.053053176 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDPTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5089|beta-lactamase_C75H|0.052113966 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLHGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5090|beta-lactamase_T69K|0.052113966 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSKFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5091|beta-lactamase_I259H|0.05169567 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVHYTTGSQATMDERNRQIAEIGASLIKHW ->5092|beta-lactamase_M209K|0.050609861 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWKEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5093|beta-lactamase_L191R|0.050318618 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKRLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5094|beta-lactamase_T69D|0.049721472 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSDFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5095|beta-lactamase_K232I|0.049563145 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADISGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5096|beta-lactamase_I125Y|0.048980659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAYTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5097|beta-lactamase_E210P|0.048980659 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMPADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5098|beta-lactamase_L282P|0.046266624000000006 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASPIKHW ->5099|beta-lactamase_M66K|0.045980268 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPKMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5100|beta-lactamase_W227D|0.044909118 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGDFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5101|beta-lactamase_L146P|0.044714631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEPTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5102|beta-lactamase_M1G|0.044595397 -GSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5103|beta-lactamase_T187P|0.044327609 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATPLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5104|beta-lactamase_L150K|0.043551613 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFKHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5105|beta-lactamase_A133E|0.043408923 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAENLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5106|beta-lactamase_T158P|0.042483395 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVPRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5107|beta-lactamase_C121H|0.040836601 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELHSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5108|beta-lactamase_L120K|0.040836601 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREKCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5109|beta-lactamase_L74D|0.040836601 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLDCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5110|beta-lactamase_W208P|0.040836601 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDPMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5111|beta-lactamase_R59P|0.039583669 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFPPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5112|beta-lactamase_V257K|0.038265256 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIKVIYTTGSQATMDERNRQIAEIGASLIKHW ->5113|beta-lactamase_G43Y|0.036394654 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVYYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5114|beta-lactamase_L136R|0.035720299 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLRLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5115|beta-lactamase_Y260G|0.035638204 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIGTTGSQATMDERNRQIAEIGASLIKHW ->5116|beta-lactamase_L146K|0.034728313 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEKTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5117|beta-lactamase_S68P|0.033382535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMPTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5118|beta-lactamase_A133I|0.031063341 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAINLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5119|beta-lactamase_Y260E|0.031063341 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIETTGSQATMDERNRQIAEIGASLIKHW ->5120|beta-lactamase_I278Q|0.030214044 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEQGASLIKHW ->5121|beta-lactamase_K232D|0.029977531 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADDSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5122|beta-lactamase_L146R|0.029077414 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKERTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5123|beta-lactamase_K71H|0.028620025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFHVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5124|beta-lactamase_P181E|0.028620025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMEAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5125|beta-lactamase_L79K|0.028620025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVKSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5126|beta-lactamase_A123P|0.028620025 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSPAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5127|beta-lactamase_Y260K|0.027509783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIKTTGSQATMDERNRQIAEIGASLIKHW ->5128|beta-lactamase_A246P|0.027509783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAPLGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5129|beta-lactamase_N130F|0.027509783 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDFTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5130|beta-lactamase_I256H|0.026874521 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRHVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5131|beta-lactamase_D155R|0.026874521 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGRHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5132|beta-lactamase_G76R|0.025964631 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCRAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5133|beta-lactamase_M66R|0.025905014 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPRMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5134|beta-lactamase_L136F|0.025615725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLFLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5135|beta-lactamase_M184R|0.025342074 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAARATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5136|beta-lactamase_K232E|0.024547508 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADESGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5137|beta-lactamase_G234R|0.02379008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSRAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5138|beta-lactamase_G248L|0.02338449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALLPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5139|beta-lactamase_K232G|0.02213449 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADGSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5140|beta-lactamase_G43L|0.022041644 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVLYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5141|beta-lactamase_T179P|0.020615725 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTPMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5142|beta-lactamase_F70P|0.019894459 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTPKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5143|beta-lactamase_I278D|0.019894459 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEDGASLIKHW ->5144|beta-lactamase_V42K|0.019894459 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARKGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5145|beta-lactamase_G234V|0.019660878 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSVAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5146|beta-lactamase_G43V|0.01959051 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVVYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5147|beta-lactamase_A132V|0.019457594 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTVANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5148|beta-lactamase_G234T|0.018190979 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSTAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5149|beta-lactamase_D129G|0.018148954 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSGNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5150|beta-lactamase_L205G|0.017308453999999997 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQGIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5151|beta-lactamase_A133D|0.017029916000000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTADNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5152|beta-lactamase_A185P|0.014526007 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMPTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5153|beta-lactamase_F64G|0.014183943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERGPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5154|beta-lactamase_I259E|0.013685506000000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVEYTTGSQATMDERNRQIAEIGASLIKHW ->5155|beta-lactamase_I256K|0.012913419 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRKVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5156|beta-lactamase_L247D|0.011515842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAADGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5157|beta-lactamase_E164M|0.011515842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWMPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5158|beta-lactamase_S128N|0.011515842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMNDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5159|beta-lactamase_N134P|0.011515842 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAPLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5160|beta-lactamase_G242R|0.011261738 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRRIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5161|beta-lactamase_S68N|0.010294185 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMNTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5162|beta-lactamase_A235P|0.0100694 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGPGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5163|beta-lactamase_Y44R|0.009971667 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGRIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5164|beta-lactamase_I275D|0.009424365 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQDAEIGASLIKHW ->5165|beta-lactamase_N130R|0.009424365 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDRTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5166|beta-lactamase_I275K|0.008818423 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQKAEIGASLIKHW ->5167|beta-lactamase_Y260D|0.00872069 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIDTTGSQATMDERNRQIAEIGASLIKHW ->5168|beta-lactamase_K71T|0.008261346999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFTVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5169|beta-lactamase_V72D|0.008261346999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKDLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5170|beta-lactamase_E164T|0.008261346999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWTPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5171|beta-lactamase_E164V|0.008261346999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWVPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5172|beta-lactamase_D129K|0.007606538 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSKNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5173|beta-lactamase_A132E|0.0074013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTEANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5174|beta-lactamase_G43W|0.0074013 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVWYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5175|beta-lactamase_V42D|0.007010369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARDGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5176|beta-lactamase_G236P|0.007010369 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAPERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5177|beta-lactamase_S68H|0.006345788000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMHTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5178|beta-lactamase_G76K|0.005935311 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCKAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5179|beta-lactamase_K232H|0.005935311 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADHSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5180|beta-lactamase_K232Q|0.005935311 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADQSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5181|beta-lactamase_K71S|0.005935311 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFSVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5182|beta-lactamase_T179D|0.005935311 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTDMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5183|beta-lactamase_I256R|0.00560302 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRRVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5184|beta-lactamase_K232Y|0.005300049 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADYSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5185|beta-lactamase_A230P|0.005300049 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIPDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5186|beta-lactamase_A124K|0.004997078 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAKITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5187|beta-lactamase_I244K|0.004752746 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIKAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5188|beta-lactamase_C121Y|0.004713653 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELYSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5189|beta-lactamase_S68G|0.004469322 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMGTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5190|beta-lactamase_C121D|0.004185897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELDSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5191|beta-lactamase_C75K|0.004185897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLKGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5192|beta-lactamase_I259D|0.004185897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVDYTTGSQATMDERNRQIAEIGASLIKHW ->5193|beta-lactamase_L79P|0.004185897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVPSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5194|beta-lactamase_T158E|0.004185897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVERLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5195|beta-lactamase_S128I|0.004185897 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMIDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5196|beta-lactamase_V257R|0.003140158 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIRVIYTTGSQATMDERNRQIAEIGASLIKHW ->5197|beta-lactamase_L188R|0.003101065 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTRRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5198|beta-lactamase_I278E|0.0028274140000000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEEGASLIKHW ->5199|beta-lactamase_V42P|0.0028274140000000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARPGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5200|beta-lactamase_Y44N|0.0024462570000000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGNIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5201|beta-lactamase_K71N|0.001742582 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFNVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5202|beta-lactamase_P181K|0.001273466 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMKAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5203|beta-lactamase_V42R|0.001273466 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARRGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5204|beta-lactamase_I243K|0.000853215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGKIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5205|beta-lactamase_T69R|0.000853215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSRFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5206|beta-lactamase_S128A|0.000853215 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMADNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5207|beta-lactamase_I278K|0.000472058 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEKGASLIKHW ->5208|beta-lactamase_N130K|0.000472058 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDKTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5209|beta-lactamase_L150R|0.000198407 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFRHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5210|beta-lactamase_I244D|-3.620000000000001e-05 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIDAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5211|beta-lactamase_D129A|-0.000251163 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSANTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5212|beta-lactamase_S68L|-0.000309803 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMLTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5213|beta-lactamase_I244P|-0.000407535 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIPAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5214|beta-lactamase_T179R|-0.0007691460000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTRMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5215|beta-lactamase_A133R|-0.000788692 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTARNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5216|beta-lactamase_S68R|-0.000905971 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMRTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5217|beta-lactamase_P181R|-0.000964611 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMRAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5218|beta-lactamase_I244R|-0.00105257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIRAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5219|beta-lactamase_L205R|-0.00105257 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQRIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5220|beta-lactamase_C75R|-0.001287129 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLRGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5221|beta-lactamase_C75W|-0.0015119139999999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLWGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5222|beta-lactamase_I259K|-0.0015119139999999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVKYTTGSQATMDERNRQIAEIGASLIKHW ->5223|beta-lactamase_M67P|-0.0015119139999999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMPSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5224|beta-lactamase_E164A|-0.0015119139999999998 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWAPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5225|beta-lactamase_I125R|-0.0016878320000000002 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAARTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5226|beta-lactamase_S68A|-0.001726925 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMATFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5227|beta-lactamase_P181D|-0.001922391 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMDAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5228|beta-lactamase_T179K|-0.002020123 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTKMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5229|beta-lactamase_A185E|-0.002284001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMETTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5230|beta-lactamase_T179N|-0.002284001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTNMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5231|beta-lactamase_L188P|-0.002440373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTPRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5232|beta-lactamase_L135P|-0.002440373 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANPLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5233|beta-lactamase_A185D|-0.002596746 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMDTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5234|beta-lactamase_S68T|-0.002596746 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMTTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5235|beta-lactamase_V78R|-0.002792211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGARLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5236|beta-lactamase_L247K|-0.002889943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAKGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5237|beta-lactamase_T158K|-0.002889943 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVKRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5238|beta-lactamase_L136P|-0.0030854090000000003 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLPLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5239|beta-lactamase_L136D|-0.003144048 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLDLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5240|beta-lactamase_G43D|-0.003378606 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVDYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5241|beta-lactamase_W227K|-0.003378606 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGKFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5242|beta-lactamase_G242I|-0.003486112 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRIIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5243|beta-lactamase_A245D|-0.003583845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIDALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5244|beta-lactamase_S68D|-0.003583845 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMDTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5245|beta-lactamase_V72R|-0.00377931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKRLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5246|beta-lactamase_S68V|-0.00377931 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMVTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5247|beta-lactamase_T179H|-0.003955229 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTHMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5248|beta-lactamase_A230D|-0.004043188 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIDDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5249|beta-lactamase_G43R|-0.004267973 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVRYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5250|beta-lactamase_S128R|-0.0043461590000000005 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMRDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5251|beta-lactamase_G43E|-0.004414572 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVEYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5252|beta-lactamase_G242Y|-0.004473211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRYIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5253|beta-lactamase_T179E|-0.004473211 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTEMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5254|beta-lactamase_A124R|-0.004776183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSARITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5255|beta-lactamase_A132R|-0.004776183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTRANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5256|beta-lactamase_I243P|-0.004776183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGPIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5257|beta-lactamase_L47P|-0.004776183 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIEPDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5258|beta-lactamase_A245R|-0.004844595 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIRALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5259|beta-lactamase_I259R|-0.004873915 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVRYTTGSQATMDERNRQIAEIGASLIKHW ->5260|beta-lactamase_L137P|-0.004913008 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLPTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5261|beta-lactamase_A245K|-0.004971648 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIKALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5262|beta-lactamase_T158R|-0.00506938 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVRRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5263|beta-lactamase_L191P|-0.00515734 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKPLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5264|beta-lactamase_I278R|-0.005235526 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAERGASLIKHW ->5265|beta-lactamase_P181Y|-0.005753509 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMYAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5266|beta-lactamase_D129R|-0.005782828 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSRNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5267|beta-lactamase_D129H|-0.005909881 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSHNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5268|beta-lactamase_A245E|-0.00599784 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIEALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5269|beta-lactamase_A245P|-0.006036933 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIPALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5270|beta-lactamase_D129V|-0.006036933 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSVNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5271|beta-lactamase_D129L|-0.006183531999999999 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSLNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5272|beta-lactamase_K232L|-0.006251945 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADLSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5273|beta-lactamase_T179Q|-0.006427864 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTQMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5274|beta-lactamase_I243R|-0.00644741 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGRIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5275|beta-lactamase_G242P|-0.006730835 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRPIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5276|beta-lactamase_L73R|-0.006809021 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVRLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5277|beta-lactamase_G242L|-0.007356323 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRLIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5278|beta-lactamase_A124F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAFITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5279|beta-lactamase_A124H|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAHITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5280|beta-lactamase_A124P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAPITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5281|beta-lactamase_A124Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAYITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5282|beta-lactamase_A132K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTKANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5283|beta-lactamase_A132L|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTLANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5284|beta-lactamase_A132M|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTMANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5285|beta-lactamase_A132P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTPANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5286|beta-lactamase_A133L|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTALNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5287|beta-lactamase_A133Q|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAQNLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5288|beta-lactamase_A185K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMKTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5289|beta-lactamase_A185R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMRTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5290|beta-lactamase_A185Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMYTTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5291|beta-lactamase_A245H|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIHALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5292|beta-lactamase_C121K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELKSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5293|beta-lactamase_C121P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELPSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5294|beta-lactamase_C121R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELRSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5295|beta-lactamase_C121W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELWSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5296|beta-lactamase_C75Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLYGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5297|beta-lactamase_D129F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSFNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5298|beta-lactamase_D129I|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSINTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5299|beta-lactamase_D129M|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSMNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5300|beta-lactamase_D129P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSPNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5301|beta-lactamase_D129Q|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSQNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5302|beta-lactamase_D129T|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSTNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5303|beta-lactamase_D129W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSWNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5304|beta-lactamase_D129Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSYNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5305|beta-lactamase_G242F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRFIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5306|beta-lactamase_G242K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRKIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5307|beta-lactamase_G242W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRWIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5308|beta-lactamase_G248P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALPPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5309|beta-lactamase_G43I|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVIYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5310|beta-lactamase_G43K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVKYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5311|beta-lactamase_G43M|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVMYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5312|beta-lactamase_G43N|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVNYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5313|beta-lactamase_I125K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAKTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5314|beta-lactamase_I125P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAPTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5315|beta-lactamase_I125W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAWTMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5316|beta-lactamase_I244W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIWAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5317|beta-lactamase_I256P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRPVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5318|beta-lactamase_I259P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVPYTTGSQATMDERNRQIAEIGASLIKHW ->5319|beta-lactamase_I45P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYPELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5320|beta-lactamase_K232F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADFSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5321|beta-lactamase_K232M|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADMSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5322|beta-lactamase_K232P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADPSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5323|beta-lactamase_K232W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADWSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5324|beta-lactamase_K71E|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFEVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5325|beta-lactamase_K71I|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFIVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5326|beta-lactamase_K71P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFPVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5327|beta-lactamase_K71Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFYVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5328|beta-lactamase_L120D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREDCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5329|beta-lactamase_L120R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRERCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5330|beta-lactamase_L120W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREWCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5331|beta-lactamase_L136K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLKLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5332|beta-lactamase_L136W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLWLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5333|beta-lactamase_L136Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLYLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5334|beta-lactamase_L205D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQDIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5335|beta-lactamase_L205K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQKIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5336|beta-lactamase_L74R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLRCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5337|beta-lactamase_M184D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAADATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5338|beta-lactamase_M184P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAPATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5339|beta-lactamase_M209R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWREADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5340|beta-lactamase_P181F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMFAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5341|beta-lactamase_P181Q|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMQAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5342|beta-lactamase_P181W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMWAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5343|beta-lactamase_T179F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTFMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5344|beta-lactamase_T179W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTWMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5345|beta-lactamase_T179Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTYMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5346|beta-lactamase_T69W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSWFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5347|beta-lactamase_V257P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIPVIYTTGSQATMDERNRQIAEIGASLIKHW ->5348|beta-lactamase_V258R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVRIYTTGSQATMDERNRQIAEIGASLIKHW ->5349|beta-lactamase_V72K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKKLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5350|beta-lactamase_V78P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAPLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5351|beta-lactamase_Y260P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIPTTGSQATMDERNRQIAEIGASLIKHW ->5352|beta-lactamase_Y260R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIRTTGSQATMDERNRQIAEIGASLIKHW ->5353|beta-lactamase_Y44K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGKIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5354|beta-lactamase_Y44P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGPIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5355|beta-lactamase_F64D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERDPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5356|beta-lactamase_L146D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKEDTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5357|beta-lactamase_E164F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWFPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5358|beta-lactamase_E164G|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWGPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5359|beta-lactamase_E164N|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5360|beta-lactamase_E164S|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWSPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5361|beta-lactamase_G234D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSDAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5362|beta-lactamase_G234I|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSIAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5363|beta-lactamase_G234K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSKAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5364|beta-lactamase_G234P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSPAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5365|beta-lactamase_G234W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSWAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5366|beta-lactamase_I275P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQPAEIGASLIKHW ->5367|beta-lactamase_I275R|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQRAEIGASLIKHW ->5368|beta-lactamase_I278G|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEGGASLIKHW ->5369|beta-lactamase_I278H|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEHGASLIKHW ->5370|beta-lactamase_I278N|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAENGASLIKHW ->5371|beta-lactamase_I278P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEPGASLIKHW ->5372|beta-lactamase_M66D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPDMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5373|beta-lactamase_S233D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKDGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5374|beta-lactamase_S68E|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMETFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5375|beta-lactamase_S68F|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMFTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5376|beta-lactamase_S68I|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMITFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5377|beta-lactamase_S68K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMKTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5378|beta-lactamase_S68M|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMMTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5379|beta-lactamase_S68Q|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMQTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5380|beta-lactamase_S68W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMWTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5381|beta-lactamase_S68Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMYTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5382|beta-lactamase_S128C|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMCDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5383|beta-lactamase_S128D|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMDDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5384|beta-lactamase_S128H|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMHDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5385|beta-lactamase_S128K|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMKDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5386|beta-lactamase_S128L|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMLDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5387|beta-lactamase_S128Q|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMQDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5388|beta-lactamase_S128V|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMVDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5389|beta-lactamase_S128W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMWDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5390|beta-lactamase_S128Y|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMYDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5391|beta-lactamase_I229P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFPADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5392|beta-lactamase_N130W|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDWTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5393|beta-lactamase_R241P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSPGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5394|beta-lactamase_R255P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSPIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5395|beta-lactamase_W227P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGPFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW ->5396|beta-lactamase_R159P|-0.008030678000000001 -MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTPLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ No newline at end of file diff --git a/esm/examples/README.md b/esm/examples/README.md deleted file mode 100644 index cdbf52e..0000000 --- a/esm/examples/README.md +++ /dev/null @@ -1,10 +0,0 @@ -# What's in this directory - -* The notebooks are introduced and summarized in `../README.md` -* `some_proteins.fasta` and its smaller version, `few_proteins.fasta` are a random selection of UniRef50 sequences used in the second example of `../README.md` -* `1a3a_1_A.a3m`, `1xcr_1_A.a3m`, `5ahw_1_A.a3m` are MSAs distributed with trRosetta, used in `contact_prediction.ipynb` -* `P62593.fasta` is introduced and used in `sup_variant_prediction.ipynb` -* Example MSAs genereated in the same way as the MSAs used for MSA Transformer pre-training: - - `UniRef50_E9K9Y4.a3m`, `UniRef50_UPI0003108055.a3m`, `UniRef50_UPI0003674933.a3m`, from the same sequences as trRosetta: - `hhblits_uniclust_2017_10_1a3a_1_A.a3m`, `hhblits_uniclust_2017_10_1xcr_1_A.a3m`, `hhblits_uniclust_2017_10_5ahw_1_A.a3m`. - - Generated with: `hhblits -i UniRef50_$id.fas -oa3m UniRef50_$id.a3m -n 3 -d /uniclust30_2017_10/uniclust30_2017_10`. diff --git a/esm/examples/UniRef50_E9K9Y4.a3m b/esm/examples/UniRef50_E9K9Y4.a3m deleted file mode 100644 index e06c5da..0000000 --- a/esm/examples/UniRef50_E9K9Y4.a3m +++ /dev/null @@ -1,34 +0,0 @@ ->UniRef50_E9K9Y4 -MADNVLMAYHIVHDPDERAKHVLNTKKLYKWRITEKTKGTPVVGNVALVQTQFAKRTPVMIYATKEVANDLSDLQPVKVFTNNRDQETVNQTFDDLMR ->tr|A0A161UNY6|A0A161UNY6_LACCL Uncharacterized protein OS=Lactobacillus collinoides GN=TY91_01215 PE=4 SV=1 -MADNILMAYHIVLDPNDRTKHVLNTKKLYKWRITDKTKGTPVIGNVALVKTKFSKRVPVMIYATKEVTNDLSNLQPVKIFTTNRDQEAVNKAFDNLLK ->tr|A0A165PM23|A0A165PM23_LACPN LtrC-like protein OS=Lactobacillus plantarum GN=Nizo2891_2777 PE=4 SV=1 -MADNVLMAYHIVHDPDERAKHVLNTKKLYKWRITEQTKGTPVIGYVAT----WAKDKAVIHSAL---------------------------------- ->tr|X0PKM7|X0PKM7_9LACO Uncharacterized protein OS=Lactobacillus farraginis DSM 18382 = JCM 14108 GN=FD41_GL001280 PE=4 SV=1 -LADNVLMALHIIGNSKD-PKPHLNTNHFYKWRIDADTEGTPKIGNLAKVETQFGIQ-HVVIWGTKEVAQDISDMKRVIKFDD---------------- ->tr|A0A221N0Z6|A0A221N0Z6_LACSK Uncharacterized protein OS=Lactobacillus sakei GN=B4V05_10130 PE=4 SV=1 ---KQLIQGLHLVRDPENPKLVSLNTDKVYVWQITHQTKGTPKVGNLAVVETKKGQQ------------------------------------------ ->tr|G9ZNW5|G9ZNW5_9LACO Uncharacterized protein OS=Lactobacillus parafarraginis F0439 GN=HMPREF9103_01419 PE=4 SV=1 ----LVIGAIHIRLED--GGKRVLQTDQEFFWRITERTtnegaplqDGFPELGRVAVVPTKYGWR-PVVVVQEQRVTGeaaikAADDLKRVRRFTAND-------------- ->tr|A0A0R1W220|A0A0R1W220_9LACO Uncharacterized protein OS=Lactobacillus farraginis DSM 18382 = JCM 14108 GN=FD41_GL002732 PE=4 SV=1 ----RVIGGLHLRLEE--NGKRSLSTDQEFFWEIGKYTdnegdrlvDGFPELGRIAVVETKYGWR-PVVVVREQTVTGeaavkAADELKYVRRFTKND-------------- ->tr|C2D001|C2D001_LACBR Uncharacterized protein OS=Lactobacillus brevis subsp. gravesensis ATCC 27305 GN=HMPREF0496_0873 PE=4 SV=1 ----RVIGGLHIRLEE--DGKRTLATDHEFFWKIGKKTgnegselvDGFPELGRVAVVETKFGWR-PVLVVREQTVTGeaavkAADDLRHVSRFTAND-------------- ->tr|A0A166GPA0|A0A166GPA0_LACCL Uncharacterized protein OS=Lactobacillus collinoides GN=TY91_09755 PE=4 SV=1 --PTNIIGALHINVDDN--GQQHLNTEKIFYWRLGMYTKnatsgkkttVLPALGTIASVFTQFGRQ-DVMVVQTFQSGIDQasqtqvSHLRRVFTTSDAG-------------- ->tr|A0A0R2EPJ1|A0A0R2EPJ1_9LACO Uncharacterized protein OS=Lactobacillus similis DSM 23365 = JCM 2765 GN=FD14_GL002086 PE=4 SV=1 --SRRVISAVHLNKDEA--GELTLNLTHEYQWRTGAHTYfangepaqnTEPTVGTIAIAKTYRGDK-RVVIVDSTFVAKEVvspneliqaNRLRRITQYTDEK-------------- ->tr|A0A1Y2KRT9|A0A1Y2KRT9_LACPA Uncharacterized protein OS=Lactobacillus paracasei GN=B9J76_08465 PE=4 SV=1 ----QVLLARHFKESPDDHHLHL--VPHIYRWGITSDTTGEPQRGKIAKVQTKSGVQ-EVIVLKVKEQSPRRrpYVYQPVISFESY--------------- ->tr|A0A023D133|A0A023D133_9LACO Uncharacterized protein OS=Lactobacillus sucicola DSM 21376 = JCM 15457 GN=FD15_GL002287 PE=4 SV=1 -MPRIVIAGFHIEDDPE--KGKVLNTKKKYYWRVSAHTEnkkvdGkniEFKKGHLADVLTYRGPQ-KVFIIGVCiaeqeEVKEWAKKLQRVLKYHLE--------------- ->tr|A0A0F4KQ37|A0A0F4KQ37_9LACO Uncharacterized protein OS=Lactobacillus mellis GN=JG29_16320 PE=4 SV=1 -MVRRAVEVMHLNRNQE-TGKYYLS-HKGYFFQISSHTKdskvkkfyGrMIPLGQIVKVQTNYGWK-PAVVVKNMEVTGDFalkavKRLKRVTRITDQKL------------- ->tr|N9WER6|N9WER6_9CLOT Uncharacterized protein OS=Clostridium colicanis 209318 GN=HMPREF1092_02059 PE=4 SV=1 ----NVIKGMHFGTDE--NGNMILNNDKAFHWRIPNALTGKVNKGDMVIVRVKtkSGAikHVPVLVIDVINNFENTEnlNLKNIVR------------------- ->tr|B1BYI7|B1BYI7_CLOPF Uncharacterized protein OS=Clostridium perfringens E str. JGS1987 GN=AC3_A0261 PE=4 SV=1 ----MFIEAMHIYKf-K--DGRIKLKTSGKYIWAIPKRLEEeNISLGDIVLVPCK---knNAPVIVLNVFENNNKKFgyKHKKVIK------------------- ->tr|A0A1C6L357|A0A1C6L357_9CLOT Uncharacterised protein OS=uncultured Clostridium sp. GN=SAMEA3545266_03736 PE=4 SV=1 ----KVIEGFHIKKiqrgTK--KGQDYINHNKRYVWKIPERLEGQIEKGDIVWVHAKKDNkdiKARVLVVDVLENNDGA--LRSVIK------------------- ->tr|A0A1C6L2U1|A0A1C6L2U1_9CLOT Uncharacterised protein OS=uncultured Clostridium sp. GN=SAMEA3545266_03712 PE=4 SV=1 ----KFIEGFFIKKytrgTK--KGKEYIKTKKRYVWSIPKELENEIQVADEVLVETSwlKDGkyisgKTKVLVLNVFEKDEDQEERKKVLK------------------- diff --git a/esm/examples/UniRef50_UPI0003108055.a3m b/esm/examples/UniRef50_UPI0003108055.a3m deleted file mode 100644 index 9998487..0000000 --- a/esm/examples/UniRef50_UPI0003108055.a3m +++ /dev/null @@ -1,2078 +0,0 @@ ->UniRef50_UPI0003108055 -MPADAREYLESKHATRRFDRPAEVAGVVAFLLSDDTSFVIGAGYLVDGGYTALRAARGRLGPRRQAAPAVKLLPNTDSPR ->tr|A0A1U7CY72|A0A1U7CY72_9BACT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Paludisphaera borealis GN=fabG_9 PE=4 SV=1 -----G--RPDFPTGIKNLTTPDDIGAAVVYLSSPAGRKTTGDILYIDSGLHCAD-------------------------- ->tr|A0A1U8CPL0|A0A1U8CPL0_MESAU 3-hydroxybutyrate dehydrogenase type 2 isoform X2 OS=Mesocricetus auratus GN=Bdh2 PE=3 SV=1 --PKEGHRHASHIsYPEVSLATGSAS-----FPKPTEDRKVcvcrrSGPALRVPGLG------------------------------ ->tr|E2CEN7|E2CEN7_9RHOB Short-chain dehydrogenase/reductase SDR OS=Roseibium sp. TrichSKD4 GN=TRICHSKD4_1510 PE=3 SV=1 ---PVSQLDPSAHIPA------EWVGEAISWLSTDAGDAYKGTDCSLRDESVR---------------------------- ->tr|A0A0M1WAH7|A0A0M1WAH7_BRUAO Glucose 1-dehydrogenase II OS=Brucella abortus NCTC 8038 GN=BAUG_2384 PE=3 SV=1 ----Q---ALVALHPMGgvlagprRLQTPSCSSQATKLPSSTVHRFWSTAAIPPNNAKTP---------------------------- ->tr|F0XW91|F0XW91_AURAN Putative uncharacterized protein (Fragment) OS=Aureococcus anophagefferens GN=AURANDRAFT_14129 PE=3 SV=1 --------SKKTVAMFGGLMTPEHVTDALFDKVVDEPNAEAVLRITpLEGVAF----------------------------- ->tr|A0A1K1TLC4|A0A1K1TLC4_PANAN 3-oxoacyl-[acyl-carrier protein] reductase OS=Pantoea ananas GN=SAMN03097714_0328 PE=4 SV=1 --LTSYREQRIRKIPGKKIGDPEQCAMLAALLCSPAMFYLTGQSINIDGGYT----------------------------- ->tr|A0A1F4WI25|A0A1F4WI25_9BACT Uncharacterized protein OS=candidate division WWE3 bacterium RIFOXYC1_FULL_39_7 GN=A2415_00365 PE=4 SV=1 --PERTAKLIIKQIENGRNGEYFEPiAMVIRLLAMSRGLI------------------------------------------ ->tr|A0A0D2H5D7|A0A0D2H5D7_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.3, whole genome shotgun sequence OS=Rhinocladiella ma -----------QKTPFQRGADPAELAKAISYFLVTSPHFRPDLSWSLTVDFWL---------------------------- ->tr|A0A072P414|A0A072P414_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_09266 PE=4 SV=1 -VPESIREGWRKANVLGRLAEPVEMANVIHFLLSDKSSFITSSVRLGRSKTDCLKT------------------------- ->tr|A0A0F9JU37|A0A0F9JU37_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1716490 PE=4 SV=1 ----AQRDAMVGQMP---LIPPREMAEAVLEFVRDDSL--AGEAMGVMYGRPH---------------------------- ->tr|K1ZEB3|K1ZEB3_9ZZZZ Short chain dehydrogenase (Fragment) OS=groundwater metagenome GN=ACD_73C00042G0001 PE=4 SV=1 --------------FFKTNTKPNDVARVIKFLCEEGLkGSMSGSVFPLftNG-------------------------------- ->tr|A0A1C3NDW3|A0A1C3NDW3_9ACTN Meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase OS=Micromonospora krabiensis GN=GA0070620_6 ---------------TPPAIPATEIADAVATLLT--DDTLAGRVLVCqakeprrlllpADGWSDHV-------------------------- ->tr|A0A199YQF9|A0A199YQF9_9LACT 3-ketoacyl-ACP reductase OS=Lactococcus lactis RTB018 GN=V425_10045 PE=3 SV=1 -------ETYGQNIPDEwKMGSSSDVANF--IINDLIESEMTGKIFSVNGSeigYWQEP-------------------------- ->tr|A0A1Y2B8R8|A0A1Y2B8R8_9FUNG NAD(P)-binding protein OS=Rhizoclosmatium globosum GN=BCR33DRAFT_857106 PE=3 SV=1 ---------EASSVPVSLV--------IDAFMRAIEDESLAGDILRVtsq-KGID--V-------------------------- ->tr|A0A078AM39|A0A078AM39_STYLE Cylg protein OS=Stylonychia lemnae GN=Contig11717.g12535 PE=4 SV=1 --KLLQL-QNKQEINPKLFGQPSQISSIVATMCSEDGGFVNGETYFMQGVLG----------------------------- ->tr|A0A1M2IDY6|A0A1M2IDY6_ECOLX 3-ketoacyl-ACP reductase (Fragment) OS=Escherichia coli GN=BK384_28395 PE=4 SV=1 --TAYYDeLIAKGLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLS----------------------------- ->tr|L8WJT2|L8WJT2_THACA Short chain dehydrogenase domain-containing protein OS=Thanatephorus cucumeris (strain AG1-IA) GN=AG1IA_07788 PE=4 SV=1 ---QEMQKVWLERTPLKRMASPAEIGKSVAFLVPHSERIVNLyDRVGAIGGWRI---------------------------- ->tr|A0YDC0|A0YDC0_9GAMM Short-chain dehydrogenase/reductase SDR OS=marine gamma proteobacterium HTCC2143 GN=GP2143_03843 PE=4 SV=1 ----TAMPDVEQGRKDMGIGEPDDIAHMVTYLISDASKHINGAQIVIDNADTV---------------------------- ->tr|A0A1W9QF96|A0A1W9QF96_9DELT Uncharacterized protein OS=Sorangiineae bacterium NIC37A_2 GN=B6A08_06105 PE=4 SV=1 --------PLQGISFLSRIVKCEETRAAIVFLASEASRQLHGKTVIAARAAED---------------------------- ->tr|A0A1F6GGP0|A0A1F6GGP0_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_10530 PE=4 SV=1 --------SPEDYIPQGRFGEYSDLWPVFDLIFRADSTYQTGNNFVISGGYAL---------------------------- ->tr|A0A1N6DZN8|A0A1N6DZN8_9RHOB 3-oxoacyl-[acyl-carrier protein] reductase OS=Oceanicola litoreus GN=SAMN05444002_0181 PE=4 SV=1 ----TKDALFRSWTADGEVTTVDEIGTLAVFLLSDAGAALNGSEVVADRAMSAL--------------------------- ->tr|A0A1G1HT84|A0A1G1HT84_9BACT Uncharacterized protein OS=Nitrospirae bacterium RIFCSPHIGHO2_02_FULL_42_12 GN=A3D21_01415 PE=4 SV=1 -LPESVKDKIVSSNILNREQDMAEVVEFIYNLSK--MNNVSGQIFNLDSRIL----------------------------- ->tr|A0A1S2V5K2|A0A1S2V5K2_9PSED Uncharacterized protein OS=Pseudomonas costantinii GN=BFL40_07335 PE=4 SV=1 ------spvmFEPILNSASLGAMGTSGDVARVVCGLLQPGYIQ--ATTIKVDGGHLR---------------------------- ->tr|A0A0K2MEP9|A0A0K2MEP9_CLOBE Uncharacterized protein OS=Clostridium beijerinckii NRRL B-598 GN=X276_15185 PE=4 SV=1 -LDNSVLCEILKSTPHARFAKMSEISEMVCQLFNPKINYITGQTIVVDGGRYMI--------------------------- ->tr|L5KKQ3|L5KKQ3_PTEAL L-xylulose reductase OS=Pteropus alecto GN=PAL_GLEAN10014507 PE=3 SV=1 ----QKAKTILARIPLGRFAEVSEVVDTILFLLRAADHRLQGACgwgLPHQLSPSPTT-------------------------- ->tr|A0A1Q4F453|A0A1Q4F453_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 44-15 GN=BGP14_17035 PE=4 SV=1 ----TEDphgwikHYIEHEQVIPRAVDPLDCGYVAAFLLSGLSRSVTGQTIYIDNGDTIKL-------------------------- ->tr|A0A226EH58|A0A226EH58_FOLCA Carbonyl reductase [NADPH] 2 OS=Folsomia candida GN=Fcan01_09343 PE=4 SV=1 ----TFKAFLKFRTPTQTaHMPTDECINTMLFLMSDLTTQITGHNLTIDGGYLCT--------------------------- ->tr|A0A226D458|A0A226D458_FOLCA D-erythrulose reductase OS=Folsomia candida GN=Fcan01_26175 PE=4 SV=1 ----ISRTPLPGVCPEGNfMMGMDQVVESVLFLLSPRTAGaTTGQQLFVDNGYSVG--------------------------- ->tr|A0A0Q7ZSF3|A0A0Q7ZSF3_9ACTN Uncharacterized protein OS=Nocardioides sp. Root151 GN=ASD66_00625 PE=4 SV=1 ------RLIHPWG--QEESATADDMAAVIAFAASDEARYWNASELRLDGGARASF-------------------------- ->tr|A0A1E3HA04|A0A1E3HA04_9TREE Uncharacterized protein OS=Cryptococcus amylolentus CBS 6039 GN=L202_07743 PE=4 SV=1 ------YGGQEKLNPLQRQGFAFEIAHMTLFLVSVPVSPF----------------------------------------- ->tr|A0A1P8ND03|A0A1P8ND03_9MICO Uncharacterized protein OS=Brachybacterium sp. P6-10-X1 GN=BH708_05105 PE=4 SV=1 ---------------------DPDEVGTMILDAIHHGRLYCQPDRLMAEpiqarCQALLEA------------------------- ->tr|A0A1Q9E1T1|A0A1Q9E1T1_SYMMI 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Symbiodinium microadriaticum GN=Hpgd PE=4 SV=1 ----------ANHPLLKDQLLPEEVADAYIALIENDKLNSQAAAIMPQVS--YLHN------------------------- ->tr|A0A1C5K599|A0A1C5K599_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Micromonospora inositola GN=GA0070613_6415 PE=4 SV= -----FEQRAARNNVMGRPNDPQEVAEAIAWVLSDEARTVSGTVLEVGTLPRYSN-------------------------- ->tr|A0A1J5R2C0|A0A1J5R2C0_9ZZZZ 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=mine drainage metagenome GN=fabG_51 PE=4 SV=1 ----AYLRRLlanYPQGEHARFLTPQEVAHHVVWLLSPACAGVTGAQVMLDFGLTAG--------------------------- ->tr|A0A1R0LL84|A0A1R0LL84_9ACTN Uncharacterized protein OS=Streptomyces sp. IMTB 2501 GN=AV521_28565 PE=4 SV=1 --------------QLQDMMRPHDVAEAIVYALAQPRTM-RTLLWSMRSAASEN--------------------------- ->tr|A0A1M7R430|A0A1M7R430_9ACTN 3-oxoacyl-[acyl-carrier protein] reductase OS=Cryptosporangium aurantiacum GN=SAMN05443668_106384 PE=4 SV=1 ----GNADDIVAGLAVPRVGTSRELYEAIVYFCGDAAGWVTGQTLRVDGGGGLR--------------------------- ->tr|A0A1C5AWR1|A0A1C5AWR1_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Micromonospora carbonacea GN=GA0070563_12350 PE=4 S -----GTDGGRIAAVEAALGRPEDVASVLVLLASPVSAGLAGTVCTG---------------------------------- ->tr|A0A1X4NFX8|A0A1X4NFX8_9PROT Short-chain dehydrogenase OS=Thalassospira sp. MCCC 1A01428 GN=THS27_02760 PE=4 SV=1 ---DDWLTKAEAEQPFGKLVKPDEVAGLAAYLLAAESGVMTGAIIDYDQYVSG---------------------------- ->tr|C7DH70|C7DH70_MICA2 Short-chain dehydrogenase/reductase SDR OS=Candidatus Micrarchaeum acidiphilum ARMAN-2 GN=UNLARM2_0416 PE=4 SV=1 -----------RSEMGSQEQRPEDLAGIAEWLLGEESVLVDGVVIQADSGYRFARR------------------------- ->tr|A0A1B1MQ33|A0A1B1MQ33_STRLN 3-oxoacyl-ACP reductase OS=Streptomyces lincolnensis GN=SLINC_8497 PE=4 SV=1 -----RESMLVRQTALGRAGDPVDVAELGFYLCSKPGGYVTSQILQINGGSQHGV-------------------------- ->tr|A0A158GRJ6|A0A158GRJ6_9BURK 3-alpha-hydroxysteroid dehydrogenase OS=Caballeronia udeis GN=AWB69_03121 PE=4 SV=1 -----FEKSFVDLTPLGRITRPEDIAAMTYMLVRD-EFFETGQIFNYSGGNSLLGH------------------------- ->tr|A0A0F0F9Q7|A0A0F0F9Q7_9PSED Uncharacterized protein OS=Pseudomonas sp. 2(2015) GN=UB48_14530 PE=4 SV=1 ----QAAAA----ILKGCFRRQFRINlssDVKLlilvqkLLPQKLSTYVIDRVLPFPPV------------------------------- ->tr|A0A1F0I4X2|A0A1F0I4X2_9PSED Short-chain dehydrogenase OS=Pseudomonas sp. HMSC065H01 GN=HMPREF3014_00575 PE=4 SV=1 ----SVTRSINQRLVDGSFLSPGEIVDVVMFLLSSKSAGLYGQELIVDKGYGLR--------------------------- ->tr|A0A1H2FG99|A0A1H2FG99_9PSED NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Pseudomonas pohangensis GN=SAMN05216296_1542 PE=4 S ----QLAGQLGRRLLPGHFVDAAAVAQVIAFQLSQGARGVYGQDWVVDNGYSLRQG------------------------- ->tr|A0A1L7X994|A0A1L7X994_9HELO Related to estradiol 17-beta-dehydrogenase 8 OS=Phialocephala subalpina GN=PAC_11496 PE=4 SV=1 ----EAMEEQTKGVAMGRFGTAEEVADVVIFLFIGFEAVKKKVVIIQ---------------------------------- ->tr|A0A1S8GNY2|A0A1S8GNY2_9PROT Uncharacterized protein OS=Bombella intestini GN=AL01_07520 PE=4 SV=1 ----VLKAVADANPSKRSFSTPEDIAAVVQFLAGPGAVALHGSAIVVDEGTSLGLV------------------------- ->tr|K5B7B5|K5B7B5_MYCHD Short chain dehydrogenase family protein OS=Mycobacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) GN=C731_ ----AQLAELMqavalaGGPLINRRAHVDEVANLLLFLAGPSGRSLSGAVIPFDGGFTAK--------------------------- ->tr|L1PWV9|L1PWV9_ANAHA Putative sorbitol-6-phosphate 2-dehydrogenase OS=Anaerostipes hadrus DSM 3319 GN=HMPREF0369_02185 PE=4 SV=1 -----VLPYFKKNIPMHKLVDLQDVIQAAIFLLTDCs-SYLTGQSINLVGGEWM---------------------------- ->tr|A0A1J5E0Q0|A0A1J5E0Q0_9BACT Uncharacterized protein OS=Candidatus Desantisbacteria bacterium CG2_30_40_21 GN=AUJ95_02305 PE=4 SV=1 -----KE----QAKKMSVLHKLSSLDETASFIV--Nl-SQMTgisGQVFSLDSRVCG---------------------------- ->tr|A0A0R1SAY5|A0A0R1SAY5_9LACO Short-chain alcohol dehydrogenase OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000768 PE=3 SV=1 ---------AMQANYDQYQIGPDRVANVVAFAIDQPEDTNVSE-------FTV---------------------------- ->tr|A0A1J9S3Y1|A0A1J9S3Y1_9PEZI 3-ketoacyl-acp reductase OS=Diplodia corticola GN=BKCO1_2300094 PE=4 SV=1 ------QETQEAQ--TALAKLPEDVAKMVIQLATEESGWMAGNSVSVDGGNST---------------------------- ->tr|A0A1C5WSM7|A0A1C5WSM7_9CLOT Glucose 1-dehydrogenase OS=uncultured Clostridium sp. GN=SAMEA3545293_02424 PE=3 SV=1 -----MMVAKLDEIPT-----ADSVAIVVYGMCTRMADGVTGECIVADSGMMR---------------------------- ->tr|A0A1G3KXJ1|A0A1G3KXJ1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_36_13 GN=A2Y41_06235 PE=4 SV=1 -----------KDVHIQRLIEPEEITGLMKVAA--ENDALDATTLEITGGVLY---------------------------- ->tr|A0A1G5C7A8|A0A1G5C7A8_9RHIZ Short chain dehydrogenase OS=Rhizobium sp. NFACC06-2 GN=SAMN03159288_00835 PE=4 SV=1 --ARPPLke-------ERAVMMDPHDVDRAILLCASLNKSAVIPElhicpthmrdtskDIEVARWVGAP--------------------------- ->tr|A0A1I2U7Q0|A0A1I2U7Q0_9ACTN Short chain dehydrogenase OS=Streptomyces mirabilis GN=SAMN02787118_126103 PE=4 SV=1 --AARELIVGIDDQPIPRLADVDEVSSPVLFVATDDAGYSTGAEFVAGGGYLLG--------------------------- ->tr|A0A1Q7PQ18|A0A1Q7PQ18_9BACT Uncharacterized protein OS=Nitrospirae bacterium 13_1_40CM_2_62_10 GN=AUI21_01715 PE=4 SV=1 --YPS--------EDPGRLRAPSVAADALLRLAMCTSPSISGKAFDLENLP------------------------------ ->tr|A0A1K1RKR0|A0A1K1RKR0_9BACT 3-oxoacyl-[acyl-carrier protein] reductase OS=Chitinophaga sancti GN=SAMN05661012_03950 PE=3 SV=1 -LPDQYISNRVGNSLLKRMGTTDEISNFISYLALECPEFLINQEIVIDGGMN----------------------------- ->tr|A0A1J9SYR2|A0A1J9SYR2_9BACI 3-oxoacyl-ACP reductase OS=Bacillus sp. N35-10-4 GN=BAU26_18970 PE=3 SV=1 -VPDNKLSNFLHHTNTKALGQTEQIANIVMFLADDENSYFTSTVFKIDGGFL----------------------------- ->tr|A0A1Q4P028|A0A1Q4P028_SERMA Uncharacterized protein OS=Serratia marcescens GN=BHU62_11465 PE=3 SV=1 -LPESTYSHVLQVSAIKRTGCVKDVSSIVQLLCGDHCNYMTGQVIHIDGGKF----------------------------- ->tr|A0A1N6Y2D0|A0A1N6Y2D0_9SPIO 3-oxoacyl-[acyl-carrier protein] reductase OS=Alkalispirochaeta americana GN=SAMN05920897_1374 PE=3 SV=1 -VNESRTTKAFS---NEWNKNPEDVIPLLNFMLSFDETGPTGQTFSLTRREI----------------------------- ->tr|H3F7K4|H3F7K4_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00107707 PE=4 SV=1 -----KSgeeni-ISNSEIMLGRLGVPEEIGGIQ-FIPGNSRVrhHIDHHDLLhtddADASIHG---------------------------- ->tr|A0A1F4ZJP3|A0A1F4ZJP3_9BACT Uncharacterized protein OS=Candidatus Amesbacteria bacterium RIFOXYB1_FULL_47_13 GN=A2379_02410 PE=3 SV=1 -----NKagdem--YTKAIKQKktGGDSPELAARLVSFLISNKANHISGCLLSakwdKKGELSD---------------------------- ->tr|R5IDX5|R5IDX5_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:124 GN=BN480_01486 PE=4 SV=1 ----RYVTEYGAGVPV--APNPDEIARMILTLCTPVSDFMYGQTVEVDGGSQFS--------------------------- ->tr|A0A1L9P202|A0A1L9P202_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Planktotalea frisia GN=fabG_2 PE=4 SV=1 ----EVLANAIAQMPHGHAMQPEQIAGWVSFLAGPMGDVSSGNVFILNQGRDVR--------------------------- ->tr|A0A172X7A5|A0A172X7A5_9MICO Sugar dehydrogenase OS=Leifsonia xyli GN=A0130_13150 PE=4 SV=1 -------QKLENSIPLRTVADPSQIGDVVAFVISDGGSYLTATTVFVDGGIMHGSVG------------------------ ->tr|A0A1D2MF22|A0A1D2MF22_ORCCI L-xylulose reductase OS=Orchesella cincta GN=Ocin01_15092 PE=3 SV=1 -------ERFMQETVIK---RPIEKRNCRLGFCSF---------------------------------------------- ->tr|A0A1T5EPX8|A0A1T5EPX8_9SPHN 2-deoxy-D-gluconate 3-dehydrogenase OS=Sphingomonas histidinilytica GN=SAMN06295920_107130 PE=3 SV=1 -------ELVAKGLPPktnreLGYYPPDELAAVAVWLASEGAAMVNGRMLHASGPELQIWRM------------------------ ->tr|A0A061PFF3|A0A061PFF3_9VIBR 2-deoxy-D-gluconate 3-dehydrogenase OS=Vibrio sp. JCM 19053 GN=JCM19053_1001 PE=4 SV=1 -----LWDHIRKEQMRQNFTQPEEIADVVAFLVSEKATVSTVVPSAHLTVSRILS-------------------------- ->tr|A0A1U9KJS5|A0A1U9KJS5_ACEAC 3-oxoacyl-ACP reductase OS=Acetobacter aceti GN=A0U92_15805 PE=4 SV=1 ----NA-RRAMASLPTGQPGSPVTVARMVAELARPDAGSITGSIIDINCGLYMR--------------------------- ->tr|A0A1S8AVY7|A0A1S8AVY7_9EURY Dehydrogenase OS=Haloterrigena saccharevitans GN=A6E15_07960 PE=3 SV=1 ----DAAALLAAQGSDGVTGESMT---------AE--EWEDRLA------------------------------------- ->tr|M3C9S3|M3C9S3_SPHMS NAD(P)-binding protein OS=Sphaerulina musiva (strain SO2202) GN=SEPMUDRAFT_53690 PE=4 SV=1 -----VKGKLLEKHPFRGLGKTEDLAKVAVFLASEDVQWVTGVSVEVFFSLSF---------------------------- ->tr|F2I1K7|F2I1K7_PELSM D-beta-hydroxybutyrate dehydrogenase OS=Pelagibacter sp. (strain IMCC9063) GN=SAR11G3_01246 PE=4 SV=1 ---LDARVEmLRDKQPSLKFVRKEDIASMIFFLCSQEADQVTGSNISLDGAWTA---------------------------- ->tr|A0A1S1QRA1|A0A1S1QRA1_9ACTN Uncharacterized protein OS=Frankia sp. Cc1.17 GN=CC117_20560 PE=4 SV=1 ----FYPAWMAKGYVNSDFLDVDEIVRVIANLLENRAGtSipsitITARSIAASS-------------------------------- ->tr|A0A192IJ83|A0A192IJ83_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium NRL2 GN=TEF_11135 PE=3 SV=1 ------------------------VYPTAKWLAAFAADDMTGRVFWNRQEYRIFDEAN----------------------- ->tr|A0A1F7F211|A0A1F7F211_9BACT Uncharacterized protein OS=Candidatus Raymondbacteria bacterium RIFOXYD12_FULL_49_13 GN=A2519_20130 PE=3 SV=1 --------------GESLFGSVSDVHAAaRFILMLAQSEWSTGAIYDFDSRVYN----G----------------------- ->tr|A0A212F0Y3|A0A212F0Y3_DANPL 3-oxoacyl OS=Danaus plexippus plexippus GN=KGM_201625 PE=4 SV=1 -------QNMANQVPLKELVRAEKIAEVAALIASDRGSTITGCDYIIDSGMSLKR-------------------------- ->tr|V5H9M8|V5H9M8_IXORI Putative mitochondrial/plastidial beta-ketoacyl-acp reductase OS=Ixodes ricinus PE=2 SV=1 ----EQREMIVAQVPLGRAAQPREGGRCRCFSLLA-rELVHD-WSRD----------------------------------- ->tr|A0A1V4PSZ3|A0A1V4PSZ3_9MYCO Uncharacterized protein OS=Mycobacterium sp. AT1 GN=B1790_13295 PE=4 SV=1 -------DDAFVGADFP-VLSSHDVAHHVLNLLSPANRGINGTSVVCDFGYMAR--------------------------- ->tr|A0A242AUI5|A0A242AUI5_9ENTE Uncharacterized protein OS=Enterococcus sp. 7F3_DIV0205 GN=A5821_000204 PE=4 SV=1 --FPDIRPNYKKSVQFPYLGKAADIANGIIYLACDEASFVTGAELVIDGERVAL--------------------------- ->tr|A0A225MRC7|A0A225MRC7_9BURK 3-oxoacyl-ACP reductase OS=Candidimonas nitroreducens GN=CEY11_06395 PE=4 SV=1 -------DIKAAADVLGKAAMPDEIAQTILFLAGTGGAYTTGQILGTRIRYGQ---------------------------- ->tr|F0JRD0|F0JRD0_ESCFE Putative uncharacterized protein OS=Escherichia fergusonii ECD227 GN=ECD227_2756 PE=4 SV=1 --------QPYIGSVAGRAVNGEDMMATIRFLLSDEAQAISGTIIDIGCFFHQGSST------------------------ ->tr|A0A1G1PZX2|A0A1G1PZX2_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 GN=A2243_04790 PE=3 SV=1 -----------------RLMTPDAVVDMVMFALSVpQNACPLELAVINQ----QTPWI------------------------ ->tr|A0A0K2R3S2|A0A0K2R3S2_9MICC Gluconate 5-dehydrogenase OS=Arthrobacter sp. Hiyo4 GN=AHiyo4_28800 PE=4 SV=1 -----FNAWILGRTPAHRWGTVQDLAGRRCGWPR------TGRIL------------------------------------ ->tr|A0A1V6J951|A0A1V6J951_9BACT Diacetyl reductase ((S)-acetoin forming) OS=Bacteroidetes bacterium ADurb.Bin012 GN=butA PE=4 SV=1 -------------LGVDEAFDPEELAEFISDFAEYGFEFFNGKILPVSVTTP----------------------------- ->tr|A0A0D2BH62|A0A0D2BH62_9EURO Uncharacterized protein OS=Exophiala spinifera GN=PV08_05150 PE=4 SV=1 -----------RFTPMGRLGTAQEIADVATFLGQPTSLARSLPLMVairLNsveiyTNAIG---------------------------- ->tr|A0A0F4YJ54|A0A0F4YJ54_TALEM Uncharacterized protein OS=Rasamsonia emersonii CBS 393.64 GN=T310_8148 PE=4 SV=1 -----------SIAPMNSTSLMQTEwAPWMRWltafysyAAAKQHLFK--ALLSls--TGDTG---------------------------- ->tr|A0A137QDQ1|A0A137QDQ1_9AGAR 3-oxoacyl-[acyl-carrier-protein] reductase FabG (Fragment) OS=Leucoagaricus sp. SymC.cos GN=AN958_11464 PE=4 SV=1 -------GKLGQLIPLGCFGAPECVLQHPFP-PAdthpnateiaqaglfialDNSSYVNGQKFAVDGGVSSS--------------------------- ->tr|A0A0Q8QFX3|A0A0Q8QFX3_9BURK Short-chain dehydrogenase OS=Noviherbaspirillum sp. Root189 GN=ASE07_04755 PE=3 SV=1 -------DINTLQDPVnvakAVksvLLLPEQTVIPEIMVLPmQESSW-P---------------------------------------- ->tr|B9X9R2|B9X9R2_PEDPL Short-chain dehydrogenase/reductase SDR OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD5845 PE=3 SV=1 --------HDYLQ-PEdvae-----------TVLYLARlSPAAW-PTEIVIdRKGAAL----------------------------- ->tr|U5BUD3|U5BUD3_9BACT Short-chain dehydrogenase OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=P872_15775 PE=3 SV=1 -------DAWKIQ-SEdlgq-----------MVVDLMQmHPRTL-PSKIEVrPSMPG------------------------------ ->tr|A0A1V2PWN6|A0A1V2PWN6_9PSEU Uncharacterized protein OS=Saccharothrix sp. ALI-22-I GN=ALI22I_44740 PE=3 SV=1 ----------------------DTAAPGLVDLIDRLGPDDHGACVLPDGSHYD---------------------------- ->tr|A0A1Q6SZQ7|A0A1Q6SZQ7_9PROT Uncharacterized protein OS=Acetobacter sp. 46_36 GN=BHW56_06990 PE=4 SV=1 ----DDKEAQKRRLPSRRLGQPAEVAALVYNIITNHYAFTSGQCFNFDGGAFL---------------------------- ->tr|A0A1D2MUQ4|A0A1D2MUQ4_ORCCI 3-hydroxybutyrate dehydrogenase type 2 OS=Orchesella cincta GN=Ocin01_10226 PE=4 SV=1 --PEKARADFIARQKMGRIGTAAEIAALALYLACPESDFVLVKRELVSIvRWYVA--------------------------- ->tr|Q39YI1|Q39YI1_GEOMG Oxidoreductase, putative OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN=Gmet_0450 PE=4 SV=1 -----RAASILAHTPTKRFATVEGVVESAIALCIPQ-RHLTGNVIFCDDGYVIEG-------------------------- ->tr|A0A1Y5GWT3|A0A1Y5GWT3_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 45_16_T64 GN=A9Q99_09710 PE=3 SV=1 -----NLDVLAGGLP--MMLSPQRVATAALkgmrknkaiipvgmdsYLPYLANRYAPGIYDMIL---SRGV-------------------------- ->tr|A0A0M4LMI8|A0A0M4LMI8_9MICC Short-chain dehydrogenase OS=Arthrobacter sp. ERGS1:01 GN=AL755_17635 PE=3 SV=1 ------ARQLRELVDSGDp-TSP-----RFCSLGETDLAW------------------------------------------ ->tr|A0A1D2N1Z2|A0A1D2N1Z2_ORCCI L-xylulose reductase OS=Orchesella cincta GN=Ocin01_07401 PE=3 SV=1 ------SRTPMTGSDDHPi-IPMDDVVNTILFMSSDLCGMLSGENVVLDGGFCA---------------------------- ->tr|D2VUA9|D2VUA9_NAEGR Predicted protein OS=Naegleria gruberi GN=NAEGRDRAFT_72596 PE=4 SV=1 -----YKN-FVNLHENKELESPEKIGEILACLVDR-------FPMEWSGQ------------------------------- ->tr|A0A0N0PE07|A0A0N0PE07_PAPMA Putative oxidoreductase OS=Papilio machaon GN=RR48_01529 PE=3 SV=1 -----YVYNNLIAELGLKkILEPKEVAKLVLLVASNl-MPNMAGSSLKMDGAVIGIR-------------------------- ->tr|A0A150TPZ5|A0A150TPZ5_SORCE 3-oxoacyl-ACP reductase OS=Sorangium cellulosum GN=BE21_33090 PE=3 SV=1 --------GYRPPG--HNPQSPEEVAEGIVRAVEArRDVWETSLF-VKTASLAARV-------------------------- ->tr|A0A1E5T508|A0A1E5T508_9BACT Short chain dehydrogenase OS=Fabibacter misakiensis GN=BFP71_01870 PE=3 SV=1 --------QGSSPRDEGKMMTAEEVALGIIKAIRKrKRDIV---F-TTQGK----L-------------------------- ->tr|A0A1E4EZD1|A0A1E4EZD1_9BACT Uncharacterized protein OS=bacterium SCN 62-11 GN=ABS71_14580 PE=3 SV=1 -----------RQKVDELLVEPSEIVDIVVEFIQDd-SLVGEARFIGKSGLPPEGK-------------------------- ->tr|A0A1F3M913|A0A1F3M913_9BACT Short chain dehydrogenase OS=Bacteroidetes bacterium GWF2_41_31 GN=A2W85_06525 PE=3 SV=1 -----DENsmmtaeevALHLYKAIGRRKNKIIL-------------TKQGKLTNLINK------------------------------- ->tr|A0A1V0N4C1|A0A1V0N4C1_9EURY 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Ferroplasma acidiphilum GN=FAD_1114 PE=4 SV=1 --------FSKKFTLTGKLIDPDEVADTVLYLIRNe-SMTGQVITIDSGGEQMATD-------------------------- ->tr|A0A0D0GD63|A0A0D0GD63_9SPHI Contig109, whole genome shotgun sequence OS=Pedobacter lusitanus GN=TH53_21650 PE=3 SV=1 --------SIDTAAAKMRQLQPADIAETIVFAVTRpDHVLISELL-IRPLDQ------------------------------ ->tr|A0A1E5GCF2|A0A1E5GCF2_9ENTE Uncharacterized protein OS=Enterococcus ureasiticus GN=BCR21_13440 PE=4 SV=1 -QSHKFVEANDRSI-LKKNTQQRDLNNFLLFFISDKIEGVTGQSFNIDDRNF----------------------------- ->sp|P19871|3BHD_COMTE 3-beta-hydroxysteroid dehydrogenase OS=Comamonas testosteroni PE=1 SV=5 -------LHDPKLNRAGRAYMPERIAQLVLFLASDESSVMSGSELHADNSILGM--------------------------- ->tr|A0A090MFR3|A0A090MFR3_9BACT Uncultured bacterium genome assembly Metasoil_fosmids_resub OS=uncultured bacterium PE=3 SV=1 ---------------AGPVSDPVLVAKRVRELVDLPDLPGRGEDyla------------------------------------- ->tr|A0A1Q7UHQ9|A0A1Q7UHQ9_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_20CM_4_69_9 GN=AUG91_04610 PE=4 SV=1 ----------------DEMIRPEDCAEVVRMCtrLSPTARVPQ----VVMERMGSA--------------------------- ->tr|F6F3Z4|F6F3Z4_SPHCR 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Sphingobium chlorophenolicum L-1 GN=Sphch_3566 PE=3 SV=1 --Pl-LWNKPMAQP---RMTALPAHVAALVVWLCTDAASHVSGRDFYIQGDEV----------------------------- ->tr|A0A1J5FPF5|A0A1J5FPF5_9BACT Uncharacterized protein OS=Candidatus Moranbacteria bacterium CG2_30_45_14 GN=AUK19_02125 PE=4 SV=1 --Pe-GMLDREVGFIYMSRQGEPIEVAKFITGVMTDACSYVTGTTFKIDGGYP----------------------------- ->tr|A0A223N792|A0A223N792_ENTFL NAD(P)-dependent oxidoreductase OS=Enterococcus faecalis GN=ADH73_05570 PE=4 SV=1 --Eq-AENELYKNINCQSRLGNVKDVSNMVDFLVSEKSSYLNGEDISLNGGYK----------------------------- ->tr|A0A0K9QBK2|A0A0K9QBK2_SPIOL Uncharacterized protein (Fragment) OS=Spinacia oleracea GN=SOVF_197780 PE=4 SV=1 ------ENSpWKDRGDGGGVRIGGVFMHACGFIHY----------------------------------------------- ->tr|A0A0G4F1K4|A0A0G4F1K4_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_14665 PE=3 SV=1 -----MKKLVRSTGPL---LEVSKVAGALVDLIMDETA--HGRVLRVsnesgvsvqrypdDIGFRP---------------------------- ->tr|B5JNB0|B5JNB0_9BACT Oxidoreductase, short chain dehydrogenase/reductase family OS=Verrucomicrobiae bacterium DG1235 GN=VDG1235_3508 PE=3 SV=1 -----AWSSIDDI---CKLVAN-LSSGSY---S-----ALSGRFIHVnddlq--QLA----------------------------- ->tr|S3I3R7|S3I3R7_9RHIZ Short-chain dehydrogenase/reductase SDR OS=Rhizobium grahamii CCGE 502 GN=RGCCGE502_31342 PE=3 SV=1 -----YLPGIQKLFDDGVNVEPSRAARLIADIASGRYDALAGRLLRGIDDRD----------------------------- ->tr|G2IKR8|G2IKR8_9SPHN Short-chain dehydrogenase/reductase SDR OS=Sphingobium sp. SYK-6 GN=SLG_27950 PE=3 SV=1 -----LVALLESTTAEESAQGMARLRRFVVALAAGEHDAMAGRYLDIEKDIP----------------------------- ->tr|A0A101Q1B4|A0A101Q1B4_STRAT Short-chain dehydrogenase OS=Streptomyces antibioticus GN=AQJ23_31805 PE=3 SV=1 -----VDGLVEA----SGALAAEDLADVVAYVTG-LPRHVNLRQIMV---------------------------------- ->tr|A0A0P0SKX2|A0A0P0SKX2_9PSEU Uncharacterized protein OS=Pseudonocardia sp. EC080619-01 GN=AD017_27730 PE=3 SV=1 -----YTE-----RLATVGLDPAVVADGIVHVLASPAQ-------VVEYALT----------------------------- ->tr|A0A1E4B7Z4|A0A1E4B7Z4_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium SCN 70-22 GN=ABS52_11355 PE=3 SV=1 --------DVRAVMM-----RSEEVADVIVFMASLPPN-------VRIDDIV----------------------------- ->tr|A0A1D8SZR1|A0A1D8SZR1_9ACTN Uncharacterized protein OS=Streptomyces pactum GN=BC342_34110 PE=4 SV=1 -----YARFVRN-HEEGGLITPEQSARALVGRMGGNAS-------GQIWDVS----------------------------- ->tr|A0A0C2VC56|A0A0C2VC56_9BACL Uncharacterized protein OS=Paenibacillus sp. VKM B-2647 GN=SD70_05770 PE=4 SV=1 ----QAKDEVLRHVPQRRFIHPDEIAFAVLFLSSPLAQGISALDLSIDNGLANT--------------------------- ->tr|F3P8A9|F3P8A9_9ACTO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Actinomyces sp. oral taxon 170 str. F0386 GN=HMPREF9056_0 ----QKAERITNTdmfmHDPVSILSPEDVADCVSFLFSEKSIRITGQRLVVSGKYEYK--------------------------- ->tr|A0A0W0Z5W7|A0A0W0Z5W7_LEGSP Short-chain dehydrogenases/reductases family protein OS=Legionella spiritensis GN=Lspi_1304 PE=4 SV=1 ----EFYKSRINKVPIREFGDPHNIAKTALFMVSPVNHYMNGSIVLVDGGITSL--------------------------- ->tr|B7RWL7|B7RWL7_9GAMM Oxidoreductase, short chain dehydrogenase/reductase family OS=marine gamma proteobacterium HTCC2148 GN=GPB2148_1699 PE=3 SV=1 ----GIEAWRDSGTYMNVGMETEQVGEAVAFALSQPAGVAIDL-LELRPKRLMK--------------------------- ->tr|K1LA32|K1LA32_9BACT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Cecembia lonarensis LW9 GN=fabG_5 PE=4 SV=1 ----DKQDAVLERQYMG-LLQPSNLVNACIFLLSESSCFINGTSFPADGGYLQ---------------------------- ->tr|A0A094R2H2|A0A094R2H2_9ZZZZ Uncharacterized protein OS=freshwater metagenome GN=GM51_3570 PE=4 SV=1 ----GGEESMKSQLVMGELVKPSELGELVVFLSSGACRHLTGSTIDVNGASYIR--------------------------- ->tr|A0A193FL05|A0A193FL05_9BORD Short-chain dehydrogenase OS=Bordetella bronchialis GN=BAU06_20965 PE=4 SV=1 -------------IDPGVLQDPANVARAVRFVLMQPEETVVPE-VMVLPMRETS--------------------------- ->tr|A0A101N3A2|A0A101N3A2_9ACTN Short-chain dehydrogenase OS=Streptomyces cellostaticus GN=AQI88_41600 PE=3 SV=1 -------------LPDRDFLSAEQLGETIVWAIGQPRGIDINT-VIVRPIGQSV--------------------------- ->tr|A0A1M3DC20|A0A1M3DC20_9SPHN Uncharacterized protein OS=Sphingomonas sp. 67-36 GN=BGO24_15050 PE=3 SV=1 ----ALDARIAGMTPMAMAPQAEDIAGPIEMLLDPAGRAITGEVWRVDAGAHLD--------------------------- ->tr|A0A222EAU8|A0A222EAU8_9RHOB 3-ketoacyl-ACP reductase OS=Antarctobacter heliothermus GN=ANTHELSMS3_04924 PE=4 SV=1 -------------TPKAERLQPDDVAAIVSLVLALPNQASVPE-IVANTRLESM--------------------------- ->tr|A0A1U6HGZ5|A0A1U6HGZ5_9SPHN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Novosphingobium mathurense GN=SAMN06295987_102383 P ----IVEAEFTADIPTGSILDVEAVGRLVTFIATAPNAAVTGQSLTVDGGYSR---------------------------- ->tr|A0A034UJ91|A0A034UJ91_9NOCA Putative oxidoreductase OS=Nocardia brasiliensis NBRC 14402 GN=NBRGN_072_00480 PE=4 SV=1 -------GELRPGEVSQGDSGPAEVAEAIRFLASRRAAHVHGALLTMNGEAGAA--------------------------- ->tr|A1UP20|A1UP20_MYCSK Short-chain dehydrogenase/reductase SDR OS=Mycobacterium sp. (strain KMS) GN=Mkms_5392 PE=3 SV=1 ----F-IDDVAGALPLGRTARPRGGRSGGAVPDVAAVEFRDGVDAVRRrrrLGGVTR--------------------------- ->tr|A0A225MRL1|A0A225MRL1_9BURK Uncharacterized protein OS=Candidimonas nitroreducens GN=CEY11_06380 PE=4 SV=1 ----DVLKSIAARKF--APLTPEDVADAVMYAVTTRaGCCPDLIELRPTEN------------------------------- ->tr|A0A1J5HSZ5|A0A1J5HSZ5_9PORP Sugar dehydrogenase OS=Porphyromonadaceae bacterium CG2_30_38_12 GN=AUK44_00940 PE=4 SV=1 ----EALNDLMKLIPYKRIGQTADIGAVAVWLVTDEADYIHGASIYVDGGMTLYPG------------------------- ->tr|A0A0F9KCE3|A0A0F9KCE3_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1421800 PE=4 SV=1 ------KSKFLKQVPLGRVISERSWRAALRFAIE--CEDFAGAQVLIDGGYTA---------------------------- ->tr|X1M172|X1M172_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_25955 PE=4 SV=1 ---ESPWMDRKFAFVLEKAPSPDDVAPFINYLASEEAAGINGKVFNIGGSIIN---------------------------- ->tr|F0YDM1|F0YDM1_AURAN Putative uncharacterized protein OS=Aureococcus anophagefferens GN=AURANDRAFT_28663 PE=4 SV=1 --PAAARAAGDRAQVMGRMGTILEAGRLCLCIAAD-MTFTTGVDHILSGGAEIGYAM------------------------ ->tr|L2GAY2|L2GAY2_COLGN 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Colletotrichum gloeosporioides (strain Nara gc5) GN=CGGC5_4737 PE=4 S --GGTFTPtAQTIPQLIKRMAEPEEIAASICFLLGDESKFVTRSEWRVDGGWLEGSLT------------------------ ->tr|A0A090DKU5|A0A090DKU5_MESPL Short-chain dehydrogenase/reductase SDR OS=Mesorhizobium plurifarium GN=MPL3356_110096 PE=4 SV=1 --LEEWMPFFLHNISMHTMIDMKEIADVAVFLASDLAPHISGQSISVCGNFESYRGP------------------------ ->tr|A0A1D2TZ48|A0A1D2TZ48_9SPHN 3-oxoacyl-[acyl-carrier-protein] reductase OS=Sphingobium sp. SCN 64-10 GN=ABS86_02905 PE=3 SV=1 --IEEETALGLASQSLKRIVPPEHVADLAHFLTTPAGRSMSGAALPIDCDLQHG--------------------------- ->tr|A0A1Q4FE96|A0A1Q4FE96_9SPHI Short-chain dehydrogenase OS=Sphingobacteriales bacterium 44-15 GN=BGP14_23140 PE=4 SV=1 --KNAAEEYINNIHPLGYCPGGDVIAEACVFLMSDKARFITGCTMPVSGGAELGYRR------------------------ ->tr|A0A077Z3V4|A0A077Z3V4_TRITR Adh short domain containing protein OS=Trichuris trichiura GN=TTRE_0000262801 PE=3 SV=1 ---------LMNADSNNRLIILPRQSNGHTIVAYD---------FLPSN-------------------------------- ->tr|A0A1Y3E807|A0A1Y3E807_9BILA Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Trichinella nativa GN=D917_00057 PE=3 SV=1 ------------VTSSRSTCSINDYAEIVLHLLSDNAHSLPSGVYAADENCTL---------------------------- ->tr|A0A1F7R0N5|A0A1F7R0N5_9BACT Uncharacterized protein OS=Candidatus Saccharibacteria bacterium RIFCSPHIGHO2_12_FULL_47_16b GN=A3F65_00605 PE=4 SV=1 -LTAEQWQTLLEMMPDKKALQPEDIASAIAEV---LISNKTGQVVVVDGGLSE---------------------------- ->tr|A0A1T4X9K5|A0A1T4X9K5_9BACT 3-oxoacyl-[acyl-carrier protein] reductase OS=Prosthecobacter debontii GN=SAMN02745166_01271 PE=4 SV=1 -LLAKHRPEVESRHTLGRLNTAEDAARFIAFLHTL--ENVSGQVFQLDSRIHR---------------------------- ->tr|A0A1V3ZWP6|A0A1V3ZWP6_RHORH Short-chain dehydrogenase (Fragment) OS=Rhodococcus rhodochrous GN=GQ85_04420 PE=4 SV=1 -IKDR--------IPAEEMLEVNDVVELVDAVLRLSSRAVLPRLVLSRAGTDA---------------------------- ->tr|A0A0I9RIL1|A0A0I9RIL1_KLEVA 3-hydroxybutyrate dehydrogenase OS=Klebsiella variicola GN=bdhA PE=3 SV=1 -----SAQLLAEKPALRGVCHPAATGrngAVSVQRCR-----CPGARRRMEYGWRL---------------------------- ->tr|A0A1V5ZBF5|A0A1V5ZBF5_9BACT Glucose 1-dehydrogenase 4 OS=Candidatus Latescibacteria bacterium ADurb.Bin168 GN=gdhIV PE=4 SV=1 --------WDKRAK-----PVAHDAAELAAFLCSEAGRFVSQSLIRYpTDGW------------------------------ ->tr|W6YC77|W6YC77_COCCA Uncharacterized protein OS=Bipolaris zeicola 26-R-13 GN=COCCADRAFT_40799 PE=4 SV=1 ----RIRDHAENLVPMKRQGRPEEIADGIYYVPQPLVH----KCLLCAISFP----------------------------- ->tr|F8QBH5|F8QBH5_SERL3 Putative uncharacterized protein OS=Serpula lacrymans var. lacrymans (strain S7.3) GN=SERLA73DRAFT_77930 PE=3 SV=1 ---LRQQVLYLTSRPRRRISLLDKVFPLMgVFILTKDSPWcFNGDPGTASV-------------------------------- ->tr|A0A1Q2HR31|A0A1Q2HR31_9BACT Putative oxidoreductase OS=Phycisphaerae bacterium L21-RPul-D3 GN=L21SP3_01605 PE=3 SV=1 ------------RPSKGQMLSARDIAEHVAAAASGSFLRTAGVVLRNCIKRIK---------------------------- ->tr|A0A0E0RBK8|A0A0E0RBK8_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=3 SV=1 ----------MDRLPMRRGGGGGGXRRWRSSACRRPPTSPaRSSASTADAPL------------------------------ ->tr|A0A1V5I6S8|A0A1V5I6S8_9BACT Putative oxidoreductase OS=Synergistetes bacterium ADurb.BinA166 GN=BWY99_01242 PE=3 SV=1 ----------LAQASRnRRvifGDDPDEAGAKNCFHPDYEEipdtyllevarARRGGEIRV----------------------------------- ->tr|A0A1V5ZXX6|A0A1V5ZXX6_9BACT D-beta-hydroxybutyrate dehydrogenase OS=Synergistetes bacterium ADurb.Bin155 GN=bdhA PE=3 SV=1 ----------LAQAAKnRRiifGDDPDEAGAKNCFHPDHEDipdtyllevarARRSGESTRV---------------------------------- ->tr|A0A0R2PQ56|A0A0R2PQ56_9ACTN Uncharacterized protein OS=Acidimicrobium sp. BACL19 MAG-120924-bin39 GN=ABR58_07525 PE=3 SV=1 --------VD----GLSSTLLPNEVADVVVAIAQGQHDaragrvlampapaavtALRRWIIEHPGGGVEL--------------------------- ->tr|A0A243RE22|A0A243RE22_9ACTN Short-chain dehydrogenase OS=Streptosporangium sp. M26 GN=CA984_30745 PE=4 SV=1 --------AA---RFIADVATLPDGGPTGQFLTEKRGQG------------------------------------------ ->tr|A0A1Q6YB70|A0A1Q6YB70_9BACT Uncharacterized protein OS=Acidobacteria bacterium 13_2_20CM_56_17 GN=AUH01_00905 PE=4 SV=1 --GEELLRKEGEKLRFGRQQKPLDAAYAVVYLLSDESSQVTGTIFHIDAGESTL--------------------------- ->tr|A0A1B1WJL8|A0A1B1WJL8_9MYCO Uncharacterized protein OS=Mycobacterium sp. djl-10 GN=BCA37_18215 PE=4 SV=1 ---DDIRPRLAERSIARRHAQPDEIAGICVYLASSASDFHTADAIRVDGGYLMA--------------------------- ->tr|A0A1Y5SDB2|A0A1Y5SDB2_9RHOB Cyclic-di-GMP-binding biofilm dispersal mediator protein OS=Pseudoruegeria aquimaris GN=bdcA PE=3 SV=1 -------K----TAPAAprsalRSGRCDLlplLAAKLLHLRRGnRGERRPARLIAVmrrSAGPTLF--------------------------- ->tr|A0A061LZK7|A0A061LZK7_9MICO 3-hydroxyacyl-CoA dehydrogenase OS=Leucobacter sp. UCD-THU GN=H490_0106880 PE=4 SV=1 --EDEIFAEHVKPIPMGRPQTVEEVGELCRFLLSDGARSISGEEIGATGGMAF---------------------------- ->tr|A0A0R2Q082|A0A0R2Q082_9ACTN Uncharacterized protein OS=Acidimicrobium sp. BACL17 MAG-120823-bin42 GN=ABR67_07290 PE=4 SV=1 ------------DSFSLGVMPVEVAGDLAMRAlteRINGSQWVVSAGFpiaqyehkdpfag------------------------------------ ->tr|A0A0G1JI81|A0A0G1JI81_9BACT Short-chain dehydrogenase/reductase SDR OS=Candidatus Wolfebacteria bacterium GW2011_GWE2_44_13 GN=UW32_C0001G0269 PE=3 SV=1 --PADVAEVLY-KTAIGEM-KPDSRLIVDTFYHERV--------------------------------------------- ->tr|A0A1B6YTG7|A0A1B6YTG7_9RHOB 3-hydroxyacyl-CoA dehydrogenase OS=Rhodobacteraceae bacterium EhC02 GN=A8B83_07015 PE=3 SV=1 --AEQARQAMADSNRHKRLISVEEVATAALWLCHPLSGSINAQCIEMAGGQVR---------------------------- ->tr|A0A1B1KF40|A0A1B1KF40_RHOOP Short-chain dehydrogenase/reductase SDR OS=Rhodococcus opacus GN=R1CP_32730 PE=3 SV=1 --YEQAEQAFVSRAALGRMVTEHEVASSV--LAMLAMPGLCAADIDLSAGMVA---------------------------- ->tr|A0A1Q7R8W2|A0A1Q7R8W2_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_1_20CM_69_28 GN=AUF60_01125 PE=3 SV=1 --PPDALRAALETTGQRGLISPEEVARAVLALCEDAQRDTNGEAMVIAEGEGD---------------------------- ->tr|A0A1Q4DE10|A0A1Q4DE10_9PSEU Dehydrogenase OS=Pseudonocardia sp. 73-21 GN=BGP03_23830 PE=3 SV=1 ------------GFPLLT---AEDVADAVEGIldrAEPGECWFVQPGRepapygfrgvpgpkgstpPPSVSWEA---------------------------- ->tr|J9A6Z6|J9A6Z6_9PROT Uncharacterized protein OS=alpha proteobacterium IMCC14465 GN=IMCC14465_05240 PE=3 SV=1 -----------------PEA-vDASIAA---KTIIDGlgkkpvliftPYYAKISYFlnrfipnFMAKGGDD---------------------------- ->tr|A0A0C1WVH4|A0A0C1WVH4_9CHRO Short-chain dehydrogenase (Fragment) OS=Aphanocapsa montana BDHKU210001 GN=QP59_15335 PE=4 SV=1 ---------------GAGSGIGEAIakvfaeAGAHVFILERDAPKgeAVAQTIRETGG------------------------------- ->tr|A0A0S8BPT1|A0A0S8BPT1_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_01715 PE=3 SV=1 -----------------RMI-pPETVADAVCWVLQtPDSVLIRDVPIHNYRNPFE---------------------------- ->tr|D5V2S4|D5V2S4_ARCNC Short-chain dehydrogenase/reductase SDR OS=Arcobacter nitrofigilis (strain ATCC 33309 / DSM 7299 / LMG 7604 / NCTC 12251 / CI) ----------------EYEIYPDSFAKVIKQRLEED-KTNLENEFAQSINY------------------------------ ->tr|A0A136K9F9|A0A136K9F9_9BACT Dehydrogenase OS=Chlorobi bacterium OLB4 GN=UZ04_CHB001000040 PE=3 SV=1 -----------------NSE-sISDVVN---Y-VLD-aPDDIAIEEIivKPVEGNI----------------------------- ->tr|A0A1G3JWB7|A0A1G3JWB7_9SPHN 3-hydroxyacyl-CoA dehydrogenase OS=Sphingomonadales bacterium RIFCSPHIGHO2_01_FULL_65_20 GN=A2792_04560 PE=4 SV=1 ---------------PGVVA-lASENAPTRAILLAGAGTFEQAHI-TMTQGVWV---------------------------- ->tr|A0A1C5V0X4|A0A1C5V0X4_9CLOT Diacetyl reductase [(S)-acetoin forming] OS=uncultured Clostridium sp. GN=budC PE=3 SV=1 -----------------ESE-eVAEACCAI-M-NWD-dSQPVGQAYLlmysedceELKKGHVA---------------------------- ->tr|A0A1Y1VXP9|A0A1Y1VXP9_9FUNG NAD(P)-binding protein OS=Linderina pennispora GN=DL89DRAFT_260663 PE=3 SV=1 -----------------LVVSTEQVAEATVRTI-QD-KKSAGKAYVLIGNWAV---------------------------- ->tr|A0A0F2J5P2|A0A0F2J5P2_9BACT Short-chain dehydrogenase/reductase SDR OS=Candidatus Magnetoovum chiemensis GN=MCHI_000440 PE=3 SV=1 ---------LSALKKKHLLRSPQEPARLAVFLASAQSDNLTGNNGTIDYYSSF---------------------------- ->tr|A0A1G0SLW4|A0A1G0SLW4_9BACT Uncharacterized protein OS=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 GN=A3G43_04945 PE=4 SV=1 -----------PNEDPASLRTPDQVTDVFVYLASDDGIGISGQSldatsFVANPGLLS---------------------------- ->tr|A0A1C2DWD7|A0A1C2DWD7_9RHIZ Short-chain dehydrogenase OS=Mesorhizobium sp. UASWS1009 GN=QV13_11600 PE=4 SV=1 --PEAAQAKTLALHPGNRIATPSEIAKAAVFMISDECPFMNAACLVIDGGLSMLQ-------------------------- ->tr|W4XUG5|W4XUG5_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus GN=Sp-Dhyg_1 PE=4 SV=1 ---DEETAQFfekmKRNHAMRRTGTVDEVSRTIAFMASNDSSFTTGETVGIDGGCHLLVT------------------------- ->tr|R6J7Z7|R6J7Z7_9FIRM Short-chain dehydrogenase/reductase SDR OS=Phascolarctobacterium sp. CAG:207 GN=BN533_01468 PE=4 SV=1 ---DAINE-----LPDY-LMLPDKIASIVVALLSDSMQYISGVAIDVDEAKTW---------------------------- ->tr|K7L1I3|K7L1I3_SOYBN Uncharacterized protein OS=Glycine max GN=GLYMA_07G136100 PE=3 SV=1 -----SVDGIVSQTLVGRMGEAKEISALVAFLCLPAVGVSQLSLLLFIWLLNKI--------------------------- ->tr|A9PI58|A9PI58_POPTR Putative uncharacterized protein OS=Populus trichocarpa PE=2 SV=1 -----V-KELAYRTPH-gTCWRTR-RSLFCCRISLPAWAIVYN--------WTGH--------------------------- ->tr|A0A1U8E0W9|A0A1U8E0W9_CAPAN tropinone reductase homolog OS=Capsicum annuum GN=LOC107841555 PE=3 SV=1 -----INK-LVSRDSCWwSSWRAKRSSAMVSFLCFPCASSITGQVMCVDGGITIN--------------------------- ->tr|G6YF96|G6YF96_9RHIZ Uncharacterized protein OS=Mesorhizobium amorphae CCNWGS0123 GN=MEA186_23216 PE=3 SV=1 ------QMTMADTNMMKAFLKPADISQAALFLVGPGARHITAQSLNVCAGLAY---------------------------- ->tr|C6VW32|C6VW32_DYAFD Short-chain dehydrogenase/reductase SDR OS=Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) GN=Dfer_1939 PE=4 SV ------TNNPIRHFGAGKSGEAELIAANAMYLALPE-CRLNGLQVYMDGHCQT---------------------------- ->tr|X8JN06|X8JN06_9HOMO 3-ketoacyl-(Acyl-carrier) reductase OS=Rhizoctonia solani AG-3 Rhs1AP GN=RSOL_439980 PE=3 SV=1 -------SIKLPIDLTSKITSPEDIAGLVAFLVSPAAKNITGTIDHYSTPHPM---------------------------- ->tr|M2R7P8|M2R7P8_CERS8 Uncharacterized protein OS=Ceriporiopsis subvermispora (strain B) GN=CERSUDRAFT_116913 PE=3 SV=1 -----TATKTFGLPEGTKVMDPGVIANLVSYLVHPKTDFMTGQTIAVDSGRTM---------------------------- ->tr|A0A1J8R0I6|A0A1J8R0I6_9HOMO Uncharacterized protein OS=Rhizopogon vesiculosus GN=AZE42_12304 PE=4 SV=1 -----YFQERIDASAVGYIGQPEDVASIVSYLASKEAHFVTGKPPIQHVPNAN---------------------------- ->tr|A0A1D7QMC4|A0A1D7QMC4_9SPHI Oxidoreductase OS=Pedobacter steynii GN=BFS30_23245 PE=4 SV=1 -----SADAARERMAIKEYGTAEGIASLVAWVAGEESKYMTGTSLTMDSGTNT---------------------------- ->tr|A0A1Q7XMJ7|A0A1Q7XMJ7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium 13_1_20CM_2_68_19 GN=AUG14_05450 PE=4 SV=1 -----RWAAV----TRGRPVRLEDVVAAVVYYATCP-LSVTGRIRQVRGTTRS---------------------------- ->tr|A0A1W1GYA4|A0A1W1GYA4_9GAMM 3-oxoacyl-[acyl-carrier protein] reductase OS=Stenotrophomonas sp. 92mfcol6.1 GN=SAMN04488690_2047 PE=3 SV=1 -----PPGWMKSLLRGYPWAALPSLPRSRHWPVG----------------------------------------------- ->tr|A0A1T5K010|A0A1T5K010_9MICO NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Plantibacter cousiniae GN=SAMN06295973_2085 PE=3 SV --------------MMGRIGGPASQGAELVLAASAA-AVPSGSYLENGSVVSA---------------------------- ->tr|A0A1Y5TTA9|A0A1Y5TTA9_9PROT Enoyl-[acyl-carrier-protein] reductase [NADPH] FabL OS=Oceanibacterium hippocampi GN=fabL PE=3 SV=1 ----------DSLPPLDR-ATCEAIAEAIMRLIEDEGGADSGQIVDVERPGRT---------------------------- ->tr|A0A0T5ZDZ3|A0A0T5ZDZ3_9ARCH Short-chain dehydrogenase/reductase SDR OS=Thaumarchaeota archaeon CSP1-1 GN=XU09_C0007G0151 PE=3 SV=1 ------PTSLSAetvAKAILRAANSSrleiivpAVVRGAVWTKQTFPYLINP----IIGSTFRK--------------------------- ->tr|X1A5C1|X1A5C1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_00846 PE=4 SV=1 -------DFQNLPYALEaf-SVSSEEVGKLCV---------------EIcCSGTRKS--------------------------- ->tr|A0A0J5QZL0|A0A0J5QZL0_9BACI Uncharacterized protein OS=Bacillus pseudalcaliphilus GN=AB990_11695 PE=3 SV=1 ------GAKIGATTGPNIAATAEEIADAVIFAM-NNGKVLTGSIINCAGGQIYN--------------------------- ->tr|A0A094XJ83|A0A094XJ83_BACAO 3-oxoacyl-ACP reductase OS=Bacillus alcalophilus ATCC 27647 = CGMCC 1.3604 GN=BALCAV_0202540 PE=3 SV=1 ---------PNCD----yPLLKPSQLLPLFDQIIHNQ-GSVNGKRFEIV--------------------------------- ->tr|A0A1Q9PLX5|A0A1Q9PLX5_BACPF 3-oxoacyl-ACP reductase OS=Bacillus pseudofirmus GN=BTR22_15925 PE=4 SV=1 ---------PDCN----ySLSSPEEIARALESVVLDETMSLNGKRFEAQ--------------------------------- ->tr|A0A1W0WNN4|A0A1W0WNN4_HYPDU Dehydrogenase/reductase SDR family member 11 OS=Hypsibius dujardini GN=BV898_09162 PE=3 SV=1 ------AEAFASTATPYKVLDSEDVAEAIVYILSVPAHVNIDELTLTPQGQHAL--------------------------- ->tr|A0A0L0MBH4|A0A0L0MBH4_9BURK 3-oxoacyl-[acyl-carrier protein] reductase OS=Candidatus Burkholderia verschuerenii GN=BVER_01225c PE=3 SV=1 ------LKATVPVYRTTRrr---------CACSRNVHQSGCVVHHrTDLVCVRRPF---------------------------- ->tr|A0A087LRQ5|A0A087LRQ5_9RHIZ Short-chain dehydrogenase OS=Devosia sp. 17-2-E-8 GN=JP74_08395 PE=3 SV=1 -----EGDSW--KNTLG-VGSPEDVVGPLMFLL-SDAATMSASVLSRDMAYTK---------------------------- ->tr|A0A0D0KEZ4|A0A0D0KEZ4_9PSED Oxidoreductase OS=Pseudomonas fulva GN=RU08_20330 PE=3 SV=1 -----GAREAMREFRKIAIRPDAIARAVA--YAIEQPADVDVSELVVRPTASI---------------------------- ->tr|D2RVS6|D2RVS6_HALTV Short-chain dehydrogenase/reductase SDR OS=Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) G -----EREEI--LDPDV-MNDAA-----VLLAA-QGPDGVSGEsMPAEEWEQRL---------------------------- ->tr|A0A1N6SYI0|A0A1N6SYI0_9RHIZ 3alpha(Or 20beta)-hydroxysteroid dehydrogenase/3-oxoacyl-[acyl-carrier protein] reductase OS=Rhizobium sp. RU35A GN=SAMN0588059 -----LRKIW--KDPIE-LTPAF-----VHLAL-QDASGITDQrIRAWDMVVEL---------------------------- ->tr|A0A139AGR8|A0A139AGR8_GONPR Uncharacterized protein OS=Gonapodya prolifera JEL478 GN=M427DRAFT_44163 PE=4 SV=1 ------FKTVLAHNHRGGRGCVG------IFFPKASQ----HNQLPYQGACQR---------------------------- ->tr|A0A158GDX7|A0A158GDX7_9BURK Short-chain dehydrogenase OS=Caballeronia sordidicola GN=AWB64_02577 PE=4 SV=1 ------YAEALALNPTKRMATPQDRKCGCVHCEP-HCEFCQRHESrgrrRADsrrTAMSR---------------------------- ->tr|A0A1L9TAJ2|A0A1L9TAJ2_9EURO Uncharacterized protein OS=Aspergillus sydowii CBS 593.65 GN=ASPSYDRAFT_80307 PE=4 SV=1 ------VGERLSDSPLKSLGNVNELVkSVALLLPGRVPSVVAGSHCLVDGDIRI---------------------------- ->tr|A0A0Q5UJW1|A0A0Q5UJW1_9FLAO Uncharacterized protein OS=Flavobacterium sp. Leaf359 GN=ASG38_10845 PE=4 SV=1 ----AKIQAAKARHPMNTFGTSAEIAKV-AFHMLTEYRWVTGQVYNINGGLGTIIK------------------------- ->tr|A0A0Q8ZQW9|A0A0Q8ZQW9_9FLAO Oxidoreductase OS=Flavobacterium sp. Root901 GN=ASE21_20995 PE=4 SV=1 ----KMRETIKERHPMKNYLQSQEVAQMADYLISDSASSISGQVFVMDYGLVSFKI------------------------- ->tr|U9VZ63|U9VZ63_9CYAN Short-chain dehydrogenase OS=Leptolyngbya sp. Heron Island J GN=N836_34470 PE=4 SV=1 ---PESVAFISQLAPMNRLGTVAEMMPAVRMLLSPEGMWMNGETLYINNGYL----------------------------- ->tr|A0A1H1KUY2|A0A1H1KUY2_9MICO NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Agrococcus carbonis GN=SAMN04489719_0121 PE=4 SV=1 ---PGA--IAGRREDAGRLYNVEEFAHEVALAAVEPVPADNTRLV---GDVS----------------------------- ->tr|A0A1N5YQP9|A0A1N5YQP9_9MYCO Putative short chain dehydrogenase/reductase OS=Mycobacterium abscessus subsp. bolletii GN=SAMEA2068811_00565 PE=4 SV=1 ---DENIAWLESMSINGQIGRGDDILPVARLLVLPESGWTTAQTIFVNGGII----------------------------- ->tr|A0A1Q4UVU1|A0A1Q4UVU1_9PROT Uncharacterized protein OS=Thalassospira sp. TSL5-1 GN=LF95_07195 PE=4 SV=1 -----------LTASFGNASLVGDITSGLSFLAGPDADFITGTTFNFDHHVA----------------------------- ->tr|A0A0T5VLN2|A0A0T5VLN2_9SPHI Oxidoreductase OS=Pedobacter ginsenosidimutans GN=ASU31_18275 PE=4 SV=1 --TEEERQRTIDLHPVKKLGTVEEIGGWCVFLSSKYAGFASGTTYLIDGGRNAVL-------------------------- ->tr|A0A136M5Z1|A0A136M5Z1_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Bacteroidetes bacterium OLB12 GN=UZ12_BCD005000693 PE=3 SV=1 --PEEVFHECEEMHLLKKSGRPDRSRRVYCLSR-IGQSFIHNGASISD--------------------------------- ->tr|A0A1V0HU61|A0A1V0HU61_9RHOB Oxidoreductase OS=Rhodovulum sp. MB263 GN=B5V46_02015 PE=3 SV=1 -------------ARAAEMIQPEDMAALALHVAGMNPNVA--------IHEI----------------------------- ->tr|A0A1V4WBH0|A0A1V4WBH0_9FIRM Cyclopentanol dehydrogenase OS=Pelotomaculum sp. PtaB.Bin104 GN=cpnA PE=3 SV=1 ---VRD--LFVSRQTFpKKEGDPQLIGEFCLHIINNW--FFNRTGLVCDAGYI----------------------------- ->tr|A0A099CRC6|A0A099CRC6_9MYCO Oxidoreductase OS=Mycobacterium rufum GN=EU78_14260 PE=4 SV=1 ------DEAHREtVRLKMGRATAWETGYAVLYLLADESRFMTGQQIRLDGGATAVR-------------------------- ->tr|A0A149QGT3|A0A149QGT3_9BURK Uncharacterized protein OS=Caballeronia megalochromosomata GN=CR51_22955 PE=3 SV=1 ----DMMRSRADSVPMRWQGEGGTLVRTQHSLhrMTHDSSL---------GRYSPW--------------------------- ->tr|A0A151E3B8|A0A151E3B8_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SG8-52-4 GN=AYK24_01405 PE=4 SV=1 ------IQFPFSQVLLTRIGDL---------FPTSAYDAVPVH-MQKGDGYPV---------------------------- ->tr|A0A165U602|A0A165U602_9GAMM Uncharacterized protein OS=Halioglobus sp. HI00S01 GN=A3709_15835 PE=3 SV=1 ------H--VGTYMDvGMEAGQ---VGDAVAYalalpggvavdlleIRPNIPTPKNSQT------------------------------------- ->tr|A0A0D0SJW5|A0A0D0SJW5_9FIRM TWA4_scaffold00001, whole genome shotgun sequence OS=Lachnospiraceae bacterium TWA4 GN=P261_02286 PE=3 SV=1 ------KEFANHSVPMKRYGKEGELNSTAIFLERRNLVM------------------------------------------ ->tr|A0A1Q4BKG8|A0A1Q4BKG8_9RHIZ Short-chain dehydrogenase OS=Rhizobiales bacterium 62-17 GN=BGP04_07055 PE=3 SV=1 -------EVAAVIVlMaSMPDTTNMLD-TTILP----------------IAQPFL---------------------------- ->tr|A0A194VXL6|A0A194VXL6_9PEZI 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Valsa mali GN=VM1G_03746 PE=4 SV=1 ------EEFASKFSYLGRFGMPHEVAQSSLWLSSPGSSYITARRWRYPGDVR----------------------------- ->tr|A0A0F4YN11|A0A0F4YN11_TALEM Glucose 1-dehydrogenase OS=Rasamsonia emersonii CBS 393.64 GN=T310_7004 PE=4 SV=1 ------DEFAPNVSYLRRFGQGHEVAQGSLWLSSNAASIYKFL-------------------------------------- ->tr|A0A1Q4FDW4|A0A1Q4FDW4_9GAMM Uncharacterized protein OS=Xanthomonadales bacterium 63-13 GN=BGP25_00150 PE=4 SV=1 ---------QKNQALTGPYGAPADIVRAIEFART--AHFLNATIISVDGGRSRW--------------------------- ->tr|A0A177EUU0|A0A177EUU0_9EURO Uncharacterized protein OS=Fonsecaea monophora GN=AYO21_10028 PE=3 SV=1 -----------------STGQVEEVQQQLLRLQKDNEMeDKLPKHDTVHSVFNDYTQ------------------------- ->tr|I7CQ76|I7CQ76_NATSJ Short-chain dehydrogenase/reductase SDR OS=Natrinema sp. (strain J7-2) GN=NJ7G_0905 PE=3 SV=1 ----------DDAAALLAAQGPDGVTG-------E--SMTTDEWEDRLTES------------------------------ ->tr|E6SD15|E6SD15_INTC7 Short-chain dehydrogenase/reductase SDR OS=Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KI ----------GQDPSQGSFMEPQDIAAAVAYTLRQ-pRRMRTE-------LWTM---------------------------- ->tr|A3X0Y2|A3X0Y2_9BRAD Glucose 1-dehydrogenase OS=Nitrobacter sp. Nb-311A GN=NB311A_09306 PE=3 SV=1 ----EKMAQLPKLIPYGRIGEPETSAGPSSGLRPTRPtTSRVGHSLLMVA-------------------------------- ->tr|A0A1F7PCX4|A0A1F7PCX4_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RIFCSPLOWO2_12_FULL_71_22 GN=A3F92_14835 PE=4 SV=1 ----AYKAAAIAGTPLGRLVTEGEIARMVVLLCSAAFDFVTGRAIILDGGRTLPVF------------------------- ->tr|A0A1Z9A5B0|A0A1Z9A5B0_9EURY Oxidoreductase OS=Euryarchaeota archaeon TMED99 GN=CBC59_07040 PE=4 SV=1 -----ALNNLTQNTPLNLTVTPDQVAQGIYSFIGI-NKVVTGETMLMDGGHHL---------------------------- ->tr|A0A1Z9B6L3|A0A1Z9B6L3_9BACT Uncharacterized protein OS=bacterium TMED88 GN=CBC48_13290 PE=4 SV=1 -----VYERVMNAlawfHPRRVIDQPGPVAEAIALCCTDAAEMFAGQTVDLDGGSIF---------------------------- ->tr|A0A1F8LR51|A0A1F8LR51_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_13_48_10 GN=A2Y88_13195 PE=4 SV=1 --EWNinTLHQWLGSFPSVGLGHHSDLVSLVLFLCSDAASSLTGQVISLNLGNK----------------------------- ->tr|A0A1M4Y7G1|A0A1M4Y7G1_9BACL 3-oxoacyl-[acyl-carrier protein] reductase OS=Seinonella peptonophila GN=SAMN05444392_10682 PE=4 SV=1 ------------------FAEIEQTASSVVFLTERGAK---PTIFAATGGEVL---------------------------- ->tr|G4HDE1|G4HDE1_9BACL Short-chain dehydrogenase/reductase SDR OS=Paenibacillus lactis 154 GN=PaelaDRAFT_1994 PE=3 SV=1 --------------PLGRPNPR-RLPSLPSVLEtqaSVCCSIC----------------------------------------- ->tr|A0A0C7KVP6|A0A0C7KVP6_KLEVA HbdH protein OS=Klebsiella variicola GN=hbdH PE=3 SV=1 ----PAPSCWRKNSPPGSLSPRSN---WAKWRCFCAAMPLsrcaAPRGIWMAAGWRS---------------------------- ->tr|A0A1F8I478|A0A1F8I478_9PROT 3-hydroxybutyrate dehydrogenase OS=Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_70_19 GN=A2623_03965 PE=3 SV=1 ----VLKDVILGSQPTKRFVTTDELVGMMLYLVSDLGASANGASFSIDGGWTA---------------------------- ->tr|A0A1D2MAV5|A0A1D2MAV5_ORCCI D-beta-hydroxybutyrate dehydrogenase (Fragment) OS=Orchesella cincta GN=Ocin01_16553 PE=3 SV=1 ----AKMELLLEKQPSGEFCFSAQLLRIK---------------------------------------------------- ->tr|A0A1A7R4S6|A0A1A7R4S6_9FLAO D-beta-hydroxybutyrate dehydrogenase OS=Gelidibacter algens GN=A9996_04020 PE=3 SV=1 ----VVQKVMLKKQAVKQFIPVEAIADMALLLAKESSTTITGTSFALDGGWSA---------------------------- ->tr|W4M5R9|W4M5R9_9BACT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY2 GN=ETSY2_22310 PE=4 SV=1 ----QELEERRLRIPLERVGISVPTPWPQNDLAKrypksTPSSSRSNPhqpiRVPVAFSSTAQRI------------------------- ->tr|A0A1E5G8I7|A0A1E5G8I7_9ENTE Uncharacterized protein OS=Enterococcus ureasiticus GN=BCR21_15645 PE=4 SV=1 -------HCLRAKIPNQTFITNESVTASILFLHQENASGIRGQNLVIDNGMTIV--------------------------- ->tr|A0A1X2FFV2|A0A1X2FFV2_9MYCO Uncharacterized protein OS=Mycobacterium wolinskyi GN=AWC31_17770 PE=4 SV=1 -----------RKLPPCPTRHGSGSGRGQRLPREPARIIRHGC--RIHGERW----------------------------- ->tr|A0A1T5E6T7|A0A1T5E6T7_9SPHN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Sphingopyxis flava GN=SAMN06295937_101934 PE=3 SV=1 -----------LHLTDGATNSARQISAAVALLASELSDMTNGASLDVGGANA----------------------------- ->tr|Q0CV36|Q0CV36_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_02448 PE=3 SV=1 ----AARAVWEAENMLGPPRVPGGVPRCGPLRPERRQQ-LHDRQLAAD--------------------------------- ->tr|A0A1V4E8C9|A0A1V4E8C9_9ACTN Uncharacterized protein OS=Microbispora sp. GKU 823 GN=B1L11_27330 PE=3 SV=1 -PTDEERAEHLRRFPLGY-GGSGPIAAAVRYLVHPSGDWVSGTVMNVSGGEH----------------------------- ->tr|A0A1P8K0U8|A0A1P8K0U8_9BURK Oxidoreductase OS=Rhodoferax sp. DCY110 GN=RD110_22450 PE=3 SV=1 -PSEEDKARMLQEADLGRTIR--FIAEMPPHVCINEMVISPVWNRTYIGDRK----------------------------- ->tr|B9L366|B9L366_THERP 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase) OS=Thermomicrobium roseum (strain ATCC 2 -------DWVQGEGPHRAIHPEEELGWIVAYLCH---PNMtaisgaaipvdRGvsngigdfAELKRRSG------------------------------- ->tr|S4MI57|S4MI57_9ACTN Putative D-beta-hydroxybutyrate dehydrogenase OS=Streptomyces afghaniensis 772 GN=STAFG_6694 PE=3 SV=1 -------DWLGRFAEHAATKKITTVEQIAAVASLLASE-AgavspaR---------------------------------------- ->tr|D6TT74|D6TT74_9CHLR Short-chain dehydrogenase/reductase SDR OS=Ktedonobacter racemifer DSM 44963 GN=Krac_4617 PE=3 SV=1 -------DRFKGFYEQGTLLEPSR--PARLVVNLLRGESTgeivsiydqRGqELLKQ---------------------------------- ->tr|A0A0Q8H281|A0A0Q8H281_9BURK Short-chain dehydrogenase OS=Pelomonas sp. Root662 GN=ASD88_05415 PE=3 SV=1 --------KLQ---------DPLNVACAVRYvLQQPQGTVIPELTVLpTRES------------------------------- ->tr|D8F6Z5|D8F6Z5_9DELT Oxidoreductase, short chain dehydrogenase/reductase family protein OS=delta proteobacterium NaphS2 GN=NPH_4234 PE=3 SV=1 -------EKYKSFMD-----SPEAVARGVINqLDSER------LVVFpTEKP------------------------------- ->tr|J2S5L3|J2S5L3_9PSED Short-chain alcohol dehydrogenase OS=Pseudomonas sp. GM48 GN=PMI28_00564 PE=3 SV=1 ---------KAAQELNKIAIAPEDIGRAVAYALNQPANVTVNDLIISPTR------------------------------- ->tr|A0A0F9MZ44|A0A0F9MZ44_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1015010 PE=4 SV=1 -------------ASDEWKIQPEDIGEIVVDLLKLNSRTLPSKIEVRPSR------------------------------- ->tr|A0A1N7STA8|A0A1N7STA8_9BURK Short-chain dehydrogenase/reductase SDR OS=Paraburkholderia piptadeniae GN=BN2476_930004 PE=3 SV=1 --------NDDEAGKRGPLRQAGRNRCGRGLSREPRSRYTTGESLTVDGG------------------------------- ->tr|A0A1J1HQX4|A0A1J1HQX4_9DIPT CLUMA_CG002381, isoform A OS=Clunio marinus GN=CLUMA_CG002381 PE=3 SV=1 -------EYVAEKSVEGI-----LINKRNIFITPDYAHFIVNNLPDRVRRHLK---------------------------- ->tr|A0A1V5DY02|A0A1V5DY02_9DELT Putative oxidoreductase OS=Smithella sp. PtaU1.Bin162 GN=A4E71_00996 PE=3 SV=1 ---------VE--KTKKYMESPDKVARGIIDQLDSE------RL---VVF------------------------------- ->tr|A0A017HQV7|A0A017HQV7_9RHOB 3-oxoacyl-[acyl-carrier protein] reductase OS=Rubellimicrobium mesophilum DSM 19309 GN=Rumeso_01663 PE=3 SV=1 ------------HAPTSARHGGGTA-D-FMVSSARRARPMpsAGPTSTTAGC------------------------------- ->tr|A0A1I5CPB4|A0A1I5CPB4_9ACTN NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Geodermatophilus obscurus GN=SAMN05660359_00442 PE=3 SV=1 ----SVEDAAREVVRVARLGQDGPTGTFTSW-------------------NGMT--------------------------- ->tr|A0A1E5GWB0|A0A1E5GWB0_9ENTE Uncharacterized protein OS=Enterococcus termitis GN=BCR25_03845 PE=3 SV=1 -----KERATSES-LLDIKNNLDSLSCMLAFLSSNLSNGVTGQVFNVDSRLI----------------------------- ->tr|A0A1V5SI02|A0A1V5SI02_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Candidatus Omnitrophica bacterium ADurb.Bin277 GN=fabG_2 PE=4 SV=1 -----AMQNALERSPLRTYSDPEEVAAFLVYLSSNLVRQVTGQVFHFESRPL----------------------------- ->tr|A0A0Q7P2B3|A0A0Q7P2B3_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root483D2 GN=ASD32_15600 PE=4 SV=1 -------LRRARLPGAGTSGATDDIAFIRNDLVA-SAGWR-GW-------------------------------------- ->tr|A0A1Q7DGM3|A0A1Q7DGM3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_2_20CM_2_66_6 GN=AUI15_07975 PE=3 SV=1 ------AIEVAPGSAKPRLRSPRTRARPAAAVI------------------------------------------------ ->tr|A0A202E020|A0A202E020_9BACT Uncharacterized protein OS=bacterium K02(2017) GN=BVY03_02940 PE=4 SV=1 -----IFESSQKCAPHGGFVEPSQLAKIILLLLKPEANWLATKTIHMDGGLG----------------------------- ->tr|F3C570|F3C570_PSESG 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Pseudomonas savastanoi pv. glycinea str. race 4 GN=Pgy4_14111 PE=3 SV=1 ---SAWKNRQ--RLPSCRWGVSVWPRKLRRWrCSWPaSRVATCSSARR----------------------------------- ->tr|A0A0N0D8H7|A0A0N0D8H7_9RHOB Gluconate 5-dehydrogenase OS=Shimia sp. SK013 GN=gno_2 PE=3 SV=1 ----AVTAKLKSASALGRWGEPAELPPPSFFSPHSLQAMSLATSLPSMAGTPATIRRQ-KKTPRRS--------------- ->tr|A0A1X1EY89|A0A1X1EY89_PANCY Oxidoreductase OS=Pantoea cypripedii GN=HA50_17005 PE=4 SV=1 --YEEQVSVDLNSVPMTSVVDPADVASAMSWLISHESKHTTGSVMTIDAGFTAR--------------------------- ->tr|A0A1Q6YY77|A0A1Q6YY77_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium 13_2_20CM_2_64_8 GN=AUI04_03935 PE=4 SV=1 -MTKETVDLLILSSRPGCAhvGPRPHAAARRN-------SM------------------------------------------ ->tr|A0A1Q2Z8B8|A0A1Q2Z8B8_9ACTN Putative oxidoreductase OS=Streptomyces acidiscabies GN=Saa2_02594 PE=4 SV=1 -PTEETenpwQRRvdswLAAQRRAGRYaALPDALGNLLR--------LIGGEADALTGRYL----------------------------- ->tr|A0A0U1M3J0|A0A0U1M3J0_9EURO Uncharacterized protein OS=Talaromyces islandicus GN=bdhA PE=4 SV=1 ------QGIINAMVPIKRAAECEEVAETVAFLCSPRELHQRHEHHYRCGCHDD---------------------------- ->tr|G7XDK2|G7XDK2_ASPKW Oxidoreductase, short-chain dehydrogenase/reductase family OS=Aspergillus kawachii (strain NBRC 4308) GN=AKAW_02967 PE=3 SV=1 ------NQfdlplvgGNSDDRASGGGRSEFGICDESSGADGPRASFVTGAGWMVDGGATL---------------------------- ->tr|A2QNS5|A2QNS5_ASPNC Aspergillus niger contig An07c0190, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An07g06820 PE=4 SV= ------RAEIEAVIPIKRAAESDELRREAEGSMNMIV------DLIMGR-------------------------------- ->tr|A0A081BYK1|A0A081BYK1_9BACT Short-chain dehydrogenase/reductase SDR OS=bacterium UASB270 GN=U27_04373 PE=3 SV=1 --------YSK-QLPm-GKVGTPEEVARIVVlCSSYIm-DPLINQTLNAWWGRG------------------------------ ->tr|A0A0U1AID8|A0A0U1AID8_9MYCO 3-oxoacyl-ACP reductase OS=Mycobacterium abscessus GN=fabG_29 PE=3 SV=1 ---------TS-PYTYxvIAVGwSPPRGRQWCCWRAS-RRHWRAVRTCtarwrDLAARWT----------------------------- ->tr|A0A1S8W3Z0|A0A1S8W3Z0_9FUNG Uncharacterized protein OS=Batrachochytrium salamandrivorans GN=BSLG_01697 PE=3 SV=1 -----------------SMLVPIHLVIEAFFLAI-EDDTLKGAVirVTPKYGID----------------------------- ->tr|A0A1Q9RUW6|A0A1Q9RUW6_9PSEU Uncharacterized protein OS=Pseudonocardia sp. CNS-004 GN=BJF90_37860 PE=3 SV=1 --------DTAILFSQRSLLTPTAVADAAVALLDGRASCV-GPRPPLRGDAD----------------------------- ->tr|F4P0I8|F4P0I8_BATDJ Uncharacterized protein OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_24146 PE=3 SV=1 -----------------HMKVPISLVIDAFILGI-EDQSLKGDVirVTPEYGID----------------------------- ->tr|A0A0R2MXQ2|A0A0R2MXQ2_9LACO Acetoin dehydrogenase OS=Lactobacillus saniviri JCM 17471 = DSM 24301 GN=IV56_GL001169 PE=3 SV=1 -------DQLISQTKDRQPSKLDSVVDGVSFLAGPRSGYLTGQIMSVGNGMQ----------------------------- ->sp|Q04520|BUDC_RAOTE Diacetyl reductase [(S)-acetoin forming] OS=Raoultella terrigena GN=budC PE=3 SV=1 -------AR----L---NLPNASPLAACRSLKTSPPACRSSPARIPTI--------------------------------- ->tr|G9XEZ0|G9XEZ0_9FIRM Uncharacterized protein OS=Peptoanaerobacter stomatis GN=HMPREF9628_02143 PE=4 SV=1 ---DDDISALKEMSALNKVSYPQEIAKTILFLCSEDTSSYTGQVLSPNCGI------------------------------ ->tr|E3TDS7|E3TDS7_ICTPU Dehydrogenase/reductase sdr family member 4 OS=Ictalurus punctatus GN=DHRS4 PE=2 SV=1 ----------LKMLCIKRLGKPEDIGGVIAFLVFRRGLIHHRRDYYCHrwhqlqtiKGTMC---------------------------- ->tr|Q4S0T0|Q4S0T0_TETNG Chromosome undetermined SCAF14779, whole genome shotgun sequence OS=Tetraodon nigroviridis GN=GSTENG00025883001 PE=3 SV=1 ----------QeaaQHQKDRTSGGNRQRGGFFV---FGGGLLHHGGDHHGQrrdglptlspalasepfsdmeKKNPC---------------------------- ->tr|A0A192WHW0|A0A192WHW0_9RHIZ Short-chain dehydrogenase/reductase SDR family protein OS=Rhizobium sp. N941 GN=AMK07_PB00172 PE=4 SV=1 -----AADFQRSLTSLGRYGEPSESER--RRLSSKLRREITGATLTADGGAIALRTS------------------------ ->tr|A0A0Q6H7I7|A0A0Q6H7I7_9RHIZ Uncharacterized protein OS=Rhizobium sp. Leaf453 GN=ASG68_04120 PE=4 SV=1 ----SGLLHHRARLPGSRAISR-----------SGDVAFIRNELVASTGWR------------------------------ ->tr|A0A165NLU3|A0A165NLU3_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Pseudovibrio sp. W74 GN=fabG_13 PE=3 SV=1 ----DRPALVAAATPLGRIASLQILQRLlSGWDHPGQDS------------------------------------------- ->tr|A0A137QIM6|A0A137QIM6_9AGAR Diacetyl reductase [(S)-acetoin forming] (Fragment) OS=Leucoagaricus sp. SymC.cos GN=AN958_09270 PE=4 SV=1 ----NFVEPSMLDATYGQMGSPDQIAKLVSYLACKEAQFITGKACTSPLFQF----------------------------- ->tr|A0A0F5BZ02|A0A0F5BZ02_PRIPA Dehydrogenase OS=Pristionchus pacificus GN=PRIPAC_14091 PE=4 SV=1 ---EEARERALQSIPLNRLGQADECADVVSFLVSSILFFNDSQSSNEEGRC------------------------------ ->tr|B8XIJ9|B8XIJ9_KARVE Ketoacyl-reductase like protein OS=Karlodinium veneficum PE=2 SV=1 ---------------TGMLIQPEEIIDLMDYQLKlPANRVLKRVVFFPKGEWH----------------------------- ->tr|A0A0S8FCS5|A0A0S8FCS5_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_38_2 GN=AMS21_11360 PE=3 SV=1 ---------------LQLLAHDDRALPSRVELRPARPRPSAG--------------------------------------- ->tr|H0E8F1|H0E8F1_9ACTN Short-chain dehydrogenase/reductase SDR OS=Patulibacter medicamentivorans GN=PAI11_31120 PE=4 SV=1 --------------------APEDLAATILDLCGDPAG-ERRADVHVPGEPG----------------------------- ->tr|A0A1Q4DE10|A0A1Q4DE10_9PSEU Dehydrogenase OS=Pseudonocardia sp. 73-21 GN=BGP03_23830 PE=4 SV=1 ---------------DAVEGILDRAEPGECWFVQPGREPAP-YGFRGVPGpKGS---------------------------- ->tr|A0A1Q1FKG6|A0A1Q1FKG6_9EURY Dehydrogenase OS=Halorientalis sp. IM1011 GN=BV210_11240 PE=3 SV=1 ---------------------VMNDAATGLLA-----QGPDGVTGESMPAE------------------------------ ->tr|W7SSZ9|W7SSZ9_9PSEU 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Kutzneria sp. 744 GN=KUTG_08234 PE=3 SV=1 ----------------GALVPPDRVAGVGD------GRLRRRPVHHRHRdprrrrRAR----------------------------- ->tr|K2AGM7|K2AGM7_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_60C00009G0001 PE=4 SV=1 --PDYYQQRIS-QMPMGRFAHPSEIATYVTDLACNTSIMCAGSLIELTGGY------------------------------ ->tr|D3RUK7|D3RUK7_ALLVD Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) OS=Allochromatium vinosum (strain ATC --PDRHDRFLE-KMTYGQFVPSIEVAHYIVSLCLVESNMINGSIITIDGGV------------------------------ ->tr|W0DD59|W0DD59_CAMFE Short-chain dehydrogenase/reductase family protein OS=Campylobacter fetus subsp. venerealis cfvi03/293 GN=CFVI03293_1623 PE=4 S --PNTFNQKLQ-NSIFKEFATPNHIANFVLSMLNSNNKFINGGEFIINGGE------------------------------ ->tr|A0A099DL15|A0A099DL15_9HELI Uncharacterized protein OS=Helicobacter jaachi GN=LS71_09105 PE=4 SV=1 --EAHYKQIES-MQPLGRFGKAEEVGAFVGSVLEGHNMLMSGAIFELSGAV------------------------------ ->tr|A0A1Q7B3J7|A0A1Q7B3J7_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium 13_2_20CM_2_64_7 GN=AUI16_30425 PE=4 SV=1 ---------DTVATAAIRAirknkgiavvGRAARALWLLTRLSPAFVDWLNRRGWRSLSA------------------------------- ->tr|I0IHM6|I0IHM6_PHYMF Putative oxidoreductase OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_26050 PE=3 SV=1 --S-------ERAIPPEKALDPISVAGVIHDLVTGEREEASGSTIKLPSP------------------------------- ->tr|A0A1F9GJH1|A0A1F9GJH1_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_01_FULL_45_74 GN=A2979_04510 PE=4 SV=1 ---------TLPWIP----MKPSYIAEVIDWILSQPAHVVISSIEiqNFKKG------------------------------- ->tr|A0A1J5TPN5|A0A1J5TPN5_9EURY Uncharacterized protein OS=Marine Group III euryarchaeote CG-Epi2 GN=BET99_01270 PE=4 SV=1 ---ETASQAASQKIPIKRVNEKEEIATVLKWLLTDAPDNFTGQVLHTDGGMSKVLV------------------------- ->tr|M4ZVI3|M4ZVI3_9ACTN Putative oxidoreductase OS=Ilumatobacter coccineus YM16-304 GN=YM304_01880 PE=3 SV=1 -----------DPEYVAKWMTPAQIAQIVSELLAEg-RDGRTANSI----GLYAGY-------------------------- ->tr|A0A0F9SEA3|A0A0F9SEA3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0529920 PE=4 SV=1 -----------PVPRLLr-PPVPKNIADLALFLGS-sASDHITGELLIIRGHFPWDR-------------------------- ->tr|A0A1Q4RWR4|A0A1Q4RWR4_9CYAN Oxidoreductase OS=Calothrix sp. HK-06 GN=NIES2101_11855 PE=4 SV=1 --------------RREQLGqitnvpvveKPKDVANAIWDAVSNq-KSEVMVGSANVSQGMYRLL-------------------------- ->tr|A0A1Q6G9U8|A0A1Q6G9U8_9BACE Uncharacterized protein OS=Bacteroides plebeius GN=BHV76_10180 PE=3 SV=1 -----------SFHPLNHIIFFEQIAALAAFMIGNv-SKFQVGEVKKACATENV---------------------------- ->tr|A0A1V2PDJ6|A0A1V2PDJ6_9ACTN Dehydrogenase OS=Kribbella sp. ALI-6-A GN=BWI15_11660 PE=3 SV=1 -----------ASYPGRTVN---RVLTWPARLLPRa-A-LV-----RIAAAFNRRL-------------------------- ->tr|A0A1W2FYE8|A0A1W2FYE8_KIBAR Short chain dehydrogenase OS=Kibdelosporangium aridum GN=SAMN05661093_10566 PE=4 SV=1 ----PAADYLRGFIAVGHYGHAQDVAGMVAYPGRSW--WSPRQRKLCPGGRR----------------------------- ->tr|A0A1F4CSY7|A0A1F4CSY7_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_62_13 GN=A3G24_11460 PE=4 SV=1 ---QEAYNSILREQGIRRFGRPEELAIFIGMLASNAVEFLQGSVIDMDGGQT----------------------------- ->tr|A0A1X6ZMJ1|A0A1X6ZMJ1_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Pseudooceanicola marinus GN=fabG_10 PE=4 SV=1 -MPpEEAARQILAGIRS---GEDEIDVGKVRLlrlLLRLSPALAYGIIRRS---------------------------------- ->tr|A6WAZ2|A6WAZ2_KINRD Short-chain dehydrogenase/reductase SDR OS=Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) GN=Krad_2506 ------GDEfhrvtprsgpwvdA--EAPLRTQPMPRstsRvrwldgSVDSpcssPEGRCSERAGPL----H-VS--------------------------------- ->tr|A0A0Q6ST04|A0A0Q6ST04_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root1204 GN=ASC96_01830 PE=3 SV=1 ------RTTrrttav----ASLRRGRLP--gAG---TLAASDDIAFIRNDLV-ASTGW------------------------------ ->tr|A0A1M4RXY2|A0A1M4RXY2_9ACTO Short-chain dehydrogenase/reductase sdr OS=Actinomyces glycerinitolerans GN=ACGLYG10_1022 PE=4 SV=1 ------GQKmlehsQHYVYFPGPECDPMDQAYACLYLASKMGRAVRGQVIQVCNGAF----------------------------- ->tr|A0A239P8M2|A0A239P8M2_9BRAD 3-oxoacyl-[acyl-carrier protein] reductase OS=Tardiphaga sp. OK246 GN=SAMN05216374_6254 PE=4 SV=1 ------GSVrnrqfi---ALPAARNHTT--egIADIav-ALTCDDRADRSGRDIM-VAGAM------------------------------ ->tr|A0A1Z9UPA9|A0A1Z9UPA9_9BACT Uncharacterized protein OS=Flammeovirgaceae bacterium TMED290 GN=CBE50_06550 PE=3 SV=1 ------VEAwakr---FGTVSDSGMDVsHVAESICYALSYP----PGVAVDLLEVRP----------------------------- ->tr|A0A143PL72|A0A143PL72_9BACT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Acidobacteria bacterium DSM 100886 GN=fabG_6 PE=4 SV=1 -VTDAVRRHVGERPDLLHIATPDDVARVITYLVSEEARLITANRVHLR--------------------------------- ->tr|A0A1X7PDT3|A0A1X7PDT3_9MICO 3-oxoacyl-[acyl-carrier protein] reductase OS=Rathayibacter sp. VKM Ac-2121 GN=SAMN06295885_3319 PE=3 SV=1 -VTDEVRESVAQNDHFFDVARPEEVGDLASFLVSPAGRRVTGNVIRMA--------------------------------- ->tr|A0A1Y5F2W7|A0A1Y5F2W7_9PROT Uncharacterized protein OS=Halobacteriovorax marinus GN=A9Q84_19080 PE=4 SV=1 -------ENIKNTIPTGEFVNVEHISGLVDFFLTPASTPINGVTLPVANSMHL---------------------------- ->tr|A0A081BYK1|A0A081BYK1_9BACT Short-chain dehydrogenase/reductase SDR OS=Candidatus Vecturithrix granuli GN=U27_04373 PE=3 SV=1 ---------YSKQLPMGKVGTPEEVARIVVLCSSYIMDPLINQTLNAWWGRG----------------------------- ->tr|A5BPV5|A5BPV5_VITVI Uncharacterized protein OS=Vitis vinifera GN=VITISV_014635 PE=4 SV=1 ---------------F--VNVYSNLKGVSLEMIIKDANP---IGIIISNKS------------------------------ ->tr|A0A1W1ZYQ9|A0A1W1ZYQ9_9RHOB 3-oxoacyl-[acyl-carrier protein] reductase OS=Pseudooceanicola flagellatus GN=SAMN06295998_102258 PE=3 SV=1 ---PEQLNTIKRRTPSGSLSNDENIFKVVDMVISG-TTNMQGQVVFVDGGITS---------------------------- ->tr|A0A1R0WMP7|A0A1R0WMP7_9BACL 3-oxoacyl-ACP reductase OS=Paenibacillus odorifer GN=BSO21_31560 PE=3 SV=1 ---------NEPLPDFWRIGDAEAIASFVTALLRESDADLTGEIFAVNGSKVT---------------------------- ->tr|A0A1Z9BIV6|A0A1Z9BIV6_9BACT Uncharacterized protein OS=bacterium TMED88 GN=CBC48_08115 PE=4 SV=1 --AE-KEGRPLPSPEELGLGDPADIARVLVFMASDAAQALNAQIVSFNGRKLA---------------------------- ->tr|A4EFJ5|A4EFJ5_9RHOB Short-chain dehydrogenase/reductase SDR OS=Roseobacter sp. CCS2 GN=RCCS2_07259 PE=3 SV=1 --TLDQVRaEYAKSNPQNQLVQPSEVAELAAFLASDAARALTMEDFQVNAGSLW---------------------------- ->tr|A0A0R2TRQ2|A0A0R2TRQ2_9RHOB Uncharacterized protein OS=Rhodobacter sp. BACL10 MAG-120910-bin24 GN=ABR89_09430 PE=3 SV=1 --TNAQARaILEKSNPQGRLVQPSEIAAMVDFFCSERSPGLTNVDIQINAGADW---------------------------- ->tr|A0A1Q3QZ68|A0A1Q3QZ68_9BURK 3-hydroxybutyrate dehydrogenase OS=Hydrogenophaga sp. 70-12 GN=BGO22_15310 PE=3 SV=1 --SREdVVRqL-LVKQPSQDFVTLEQVAALAAYFVSDEAAQTRGVAWNLDGGYAA---------------------------- ->tr|A0A1Q7D6X7|A0A1Q7D6X7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium 13_1_40CM_68_15 GN=AUH30_13365 PE=3 SV=1 --SFDeAVAAMAKMNAGGRLIEPGEVAAVAVRCLRDG--GLNGEIVVLDGTEPQ---------------------------- ->tr|A0A1R1J4B6|A0A1R1J4B6_9BURK Short-chain dehydrogenase OS=Burkholderia ubonensis GN=BW685_27805 PE=3 SV=1 --GAEqFYKDTCAPLELKRFNTPVEVANLVAFLLSDEASGVTGRDWLMHTIWNQ---------------------------- ->tr|A0A1W9HFD1|A0A1W9HFD1_9PROT Short-chain dehydrogenase OS=Proteobacteria bacterium SG_bin7 GN=A4S09_16865 PE=4 SV=1 --SFEeAFKQQMGLVPLGKWSQPDEIGAYVSYLVSPKQTSITGQALHINNGALM---------------------------- ->tr|A0A0Q7DG89|A0A0Q7DG89_9CAUL Short-chain dehydrogenase OS=Phenylobacterium sp. Root1277 GN=ASC73_06185 PE=3 SV=1 ----EGGQKQMKGFPRRRLMEAEDLDASLLMLCGPAARAITGTVITIDDGQSL---------------------------- ->tr|A0A1T4NMB3|A0A1T4NMB3_9ACTN NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Marinactinospora thermotolerans DSM 45154 GN=SAMN02745673_01510 PE=4 SV=1 ----SK-LMADLIERI-DVLSSEDVAETVAFMSAVPkhVNLTEITILPTEQVI------------------------------ ->tr|B6A5H0|B6A5H0_RHILW Short-chain dehydrogenase/reductase SDR OS=Rhizobium leguminosarum bv. trifolii (strain WSM2304) GN=Rleg2_6281 PE=3 SV=1 ----KWVHQM-SAITGFGYGSKADISSVALFLASESSGFISGQNIPVCGLANI---------------------------- ->tr|A0A1S2RBK9|A0A1S2RBK9_9BACI 3-oxoacyl-ACP reductase OS=Bacillus sp. MUM 13 GN=BIV59_01105 PE=4 SV=1 --------------ADYELADPADIVAVFLYLASEASSQINGQRFMAQNFQKG---------------------------- ->tr|A0A1V5IU70|A0A1V5IU70_9BACT Putative oxidoreductase SadH OS=bacterium ADurb.BinA028 GN=sadH_2 PE=4 SV=1 ---SSTvLPDFR-----ltMDVATPAEVAEMVLAAIEDGLFYLVT---APDAGQWA---------------------------- ->tr|R4LT08|R4LT08_MYCTX Short chain dehydrogenase OS=Mycobacterium tuberculosis str. Haarlem/NITR202 GN=I917_05455 PE=4 SV=1 --AELVKNMVQT-IPLSRMGXXXGSGGHVTXSLLxvixHRGSPGRSsmSMADRSSGHD----------------------------- ->tr|S8DT73|S8DT73_FOMPI NAD-binding protein (Fragment) OS=Fomitopsis pinicola (strain FP-58527) GN=FOMPIDRAFT_55339 PE=4 SV=1 -----------------------KVLEaFDLLLKPG--SKHSGQCVEAVGDHVAFC-------------------------- ->tr|A0A165GDZ6|A0A165GDZ6_9APHY NAD(P)-binding protein OS=Laetiporus sulphureus 93-53 GN=LAESUDRAFT_711472 PE=3 SV=1 --PARLFKELVNAPG-MVVSGPEVVASLVSYLAKPESSFITEFDNATELQIH----------------------------- ->tr|A0A0H2R280|A0A0H2R280_9HOMO NAD-binding protein OS=Schizopora paradoxa GN=SCHPADRAFT_910723 PE=4 SV=1 --QLAAARKLMGLPPNTQSAEPGVVGNVVSFLCKPESHFITGQTISVDGGLV----------------------------- ->tr|B6K3K8|B6K3K8_SCHJY 3-oxoacyl-[acyl-carrier-protein] reductase Oar2 OS=Schizosaccharomyces japonicus (strain yFS275 / FY16936) GN=SJAG_03198 PE=3 S ----------------ERIASVDEVVRAATFLLFDSMCSGNIVPLH----------------------------------- ->tr|A0A1B9T6F3|A0A1B9T6F3_9RHIZ Uncharacterized protein OS=Agrobacterium rubi GN=A6U92_19140 PE=4 SV=1 ----------------SQMVTPEVVVDSVERALEAGrevn--YPGRGKLI----------------------------------- ->tr|A0A1M7MXP4|A0A1M7MXP4_9BURK 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase OS=Rhizobacter sp. OV335 GN=SAMN02787076_02694 PE=4 SV=1 ----------------E----AQDLARTIEWIHRQPahvnvqeiSLFPVAQSLYVRGIHRH---------------------------- ->tr|A0A1Z9ACR9|A0A1Z9ACR9_9EURY Uncharacterized protein OS=Euryarchaeota archaeon TMED99 GN=CBC59_00890 PE=4 SV=1 ----------------GMLCDPEEVVDQIEKDLLTDkiic--YPTKEALY----------------------------------- ->tr|A0A1H6DHR7|A0A1H6DHR7_9ACTN Uncharacterized protein OS=Streptomyces yanglinensis GN=SAMN05216223_115121 PE=4 SV=1 ---PDTQKLAAHAIAQGRIAMPDDTTAMVPAILSEAFQWATGSIIDVSGGQ------------------------------ ->tr|A0A180ER75|A0A180ER75_9BACT Uncharacterized protein OS=Lewinella sp. 4G2 GN=A3850_003505 PE=3 SV=1 -----DINNDRPYLTVRRSGHPTEIASMVKYIASDESSFISGMSYDVDGGMAIGEP------------------------- ->tr|W3XE03|W3XE03_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_02348 PE=4 SV=1 --GSLDAQAMMNEMATGRFGLPEEVAEAIVWVTSGRASLIVAGHLTPNG-------------------------------- ->tr|A0A1B8F2W5|A0A1B8F2W5_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. 05NY08 GN=VF21_04360 PE=4 SV=1 --PDKVKTSV-ATVPMGRMAEMEEVADTDDEKNDPEctnrGLSLAGTihhtaRALEDV-------------------------------- ->tr|A0A1X6PF71|A0A1X6PF71_PORUM Uncharacterized protein OS=Porphyra umbilicalis GN=BU14_0076s0034 PE=4 SV=1 ----RRP---RGGGGGGRPKEPPRLRA---ATAGPRRR------------------------------------------- ->tr|A0A239HW98|A0A239HW98_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Geodermatophilus pulveris GN=SAMN06893096_10975 PE= ---PDRVARVGPTVPMGRAGRAEEVAAPSCGCSATTPATAPAACStspaaaDQCPGR------------------------------ ->tr|A0A0D2AZE8|A0A0D2AZE8_9EURO Uncharacterized protein OS=Exophiala spinifera GN=PV08_09322 PE=4 SV=1 ---PGLREKWESQNLVDFLNQKNtealHYFVSAMLVPS----------------------------------------------- ->tr|A0A072NVS1|A0A072NVS1_9EURO Alcohol dehydrogenase OS=Exophiala aquamarina CBS 119918 GN=A1O9_12414 PE=4 SV=1 ---PHLKGLWEKENMLGRISEPSEYRGAALFCLSDASTFMTGSQVGELsmpvevDTYTVL--------------------------- ->tr|A0A1F8A0M5|A0A1F8A0M5_9EURO Short-chain dehydrogenase/reductase OS=Aspergillus bombycis GN=ABOM_005792 PE=4 SV=1 ---DDVREAFLKTIPTGKFALPEEVADAVLFLCQASISLSRYSYIGTNQLNR----------------------------- ->tr|A0A1F5QRZ1|A0A1F5QRZ1_9BACT Uncharacterized protein OS=Candidatus Eisenbacteria bacterium RBG_16_71_46 GN=A2W00_08290 PE=3 SV=1 ----------------DRNLEPSEIASLVAWICAAPEHVVVGNaTIWPLDaGVSGG--------------------------- ->tr|A0A1S9AM02|A0A1S9AM02_9BURK Short-chain dehydrogenase OS=Massilia sp. KIM GN=B0920_14580 PE=3 SV=1 ----------------IEFLKAEDVAETVGFIVALPKHANIQQvVIMPTKeGM------------------------------ ->tr|L9L2I3|L9L2I3_TUPCH Dehydrogenase/reductase SDR family member 2 OS=Tupaia chinensis GN=TREES_T100008210 PE=4 SV=1 -VARGL-------------------CGTCILPVLPGASDITSEDIVVAGF------------------------------- ->tr|A0A1Y2SU50|A0A1Y2SU50_9GAMM 3-oxoacyl-ACP reductase OS=Xenorhabdus beddingii GN=Xbed_00618 PE=4 SV=1 ------KRLSVPFHLLeKRLTLARDVAQ-VAFAIHRYFLWVTGDIITVDGGLLLGN-------------------------- ->tr|A0A1H8EP05|A0A1H8EP05_9ACTN NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Streptomyces rubidus GN=SAMN05216267_1002275 PE=4 SV=1 -SPEANSGA----------LQPADVADLVAALLAlppHaEVRLLECSSVhSAYG-------------------------------- ->tr|A0A1K1TVI7|A0A1K1TVI7_9BACL NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Thermoactinomyces sp. DSM 45891 GN=SAMN04487866_101 ------------NYDL---VDPNEVVDVFLHLASAEST-ENGERIQATEflqKRGAL--------------------------- ->tr|D3F395|D3F395_CONWI Short-chain dehydrogenase/reductase SDR OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_ --PQAFLAEKTERHPSGRLLAPEDVAEVATFLLEERAIGVNGAALLIDGGLTATFDYQ----------------------- ->tr|A0A0Q8ARN6|A0A0Q8ARN6_9MICO Uncharacterized protein OS=Microbacterium sp. Root166 GN=ASD56_02445 PE=3 SV=1 ------------NDIVGEPIVPSEITSVMRFVLSDAGSRINAQNIVVDGGYLAGVEF------------------------ ->tr|W2S1H2|W2S1H2_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_03751 PE=4 SV=1 --RKKIFDMCVGRQCVKRWGLAGDVARTVCWIAGPETEFVTGQGFDVGGGTL----------------------------- ->tr|A0A1I5Y6D1|A0A1I5Y6D1_9ACTN 3-oxoacyl-[acyl-carrier protein] reductase OS=Actinomadura madurae GN=SAMN04489713_13035 PE=4 SV=1 --ADGAFERVRDLQIVPAVEEPRDLVSTLLYVCDEGSGFLTGQTINVDGGSA----------------------------- ->tr|A0A0F4Z1Q2|A0A0F4Z1Q2_TALEM Oxidoreductase, short-chain dehydrogenase/reductase family OS=Rasamsonia emersonii CBS 393.64 GN=T310_1476 PE=4 SV=1 --SEATLRTVAAFSPFNRIAQPDEMAGTIAFLCGPDTRKnISAEYVRISQ-------------------------------- ->tr|X1I0S6|X1I0S6_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_46067 PE=4 SV=1 -----------RNLAYSKTEELERSSKIALEKAAAqgagiiedNDKIMTCSY-SSTIKEVFRIAHR----------------------- ->tr|A0A1R1HV49|A0A1R1HV49_PAEMA 3-ketoacyl-ACP reductase OS=Paenibacillus macerans GN=BK140_07015 PE=4 SV=1 ----------------DRMMQPEDVAELITATLKlPQRVFIKSAGIWTTNPQ------------------------------ ->tr|A0A0D1Z3J6|A0A0D1Z3J6_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_08927 PE=4 SV=1 --PREVFDHIKGVTPLRKVTTPDDLAGAVLFFCQSmgkWHHRTAArgrwwtrDELMAPGRIF----------------------------- ->tr|I5BWS7|I5BWS7_9BACT 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Nitritalea halalkaliphila LW7 GN=fabG PE=3 SV=1 --SDAVFDIIQANTPLQRVTSLKNWPMpacf--LHLPGHAPSPVRT--------------------------------------- ->tr|A0A1A1YAL3|A0A1A1YAL3_9MYCO Uncharacterized protein OS=Mycobacterium sp. ACS1612 GN=A5724_28595 PE=4 SV=1 ---------IASQVAWLAfVNAAEVTGTVVRvdcdgSVVSAPAVW------------------------------------------ ->tr|N1S4B2|N1S4B2_FUSC4 Trihydroxynaphthalene reductase OS=Fusarium oxysporum f. sp. cubense (strain race 4) GN=FOC4_g10001350 PE=4 SV=1 -GDKmsieEVDGEISEISPLGRPGFPMTLQELLPCWQALrrngsLVRRSTQAVELIWGTQGG---------------------------- ->tr|A0A1M5PHJ9|A0A1M5PHJ9_9EURY 3-oxoacyl-[acyl-carrier protein] reductase OS=Halobaculum gomorrense GN=SAMN05443636_1605 PE=4 SV=1 -IVEhleatgfLGHENVDTHLP-EYSCSPEEVARSVAYLVD--SEFTHGEVHSVNGGMHF---------------------------- ->tr|A0A1L3ZWB8|A0A1L3ZWB8_9SPHN Uncharacterized protein OS=Sphingomonas sp. JJ-A5 GN=BSL82_11745 PE=4 SV=1 ---AEV---gtgyVPPALRAVGTSEPTrHLAPLVAFFASPEGGLVTGQTVIADGGAWMLP-------------------------- ->tr|A0A1Q8A7G8|A0A1Q8A7G8_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 13_1_20CM_2_70_9 GN=AUG02_06870 PE=3 SV=1 ---PTA---dfprsdeYRAAQREGKLKDPAVPARAIAYLAMPSTHRNGAVLEWSDESLRTEV-------------------------- ->tr|A0A226Y739|A0A226Y739_9BURK Oxidoreductase OS=Achromobacter sp. KAs 3-5 GN=BMR85_009075 PE=4 SV=1 ---PRLRRQsvtprklldqrgpmtilrLRQRLQVGRAGRIRgHA------------RVQHG-ADVGDGG------------------------------- ->tr|A0A136MSV6|A0A136MSV6_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Omnitrophica bacterium OLB16 GN=fabG_2 PE=3 SV=1 -------GLYL---------HAADLAQTIVFLSKLPGRTLVRDMDVWGtnpgr--------------------------------- ->tr|A0A0W0ZGS2|A0A0W0ZGS2_9GAMM 3-oxoacyl-[acyl-carrier-protein] reductase OS=Legionella steelei GN=Lste_1398 PE=4 SV=1 -------REFMPDKPDDFFVKPNDVAETVFWLTQQAPSTWSFEVEIRPFG-EV---------------------------- ->tr|R1GIW7|R1GIW7_BOTPV Putative short-chain dehydrogenase reductase sdr protein OS=Botryosphaeria parva (strain UCR-NP2) GN=UCRNP2_1598 PE=4 SV=1 --------VVKGPEFVKRMEQGNSLGReMRTYVALA--------ENVV---------------------------------- ->tr|A0A0U1HT07|A0A0U1HT07_YERRO 3-ketoacyl-ACP reductase OS=Yersinia rohdei GN=fabG_4 PE=4 SV=1 -------EKIVSQQIIPKQFTPEAVSDLIEILFDARSSSLSGQILHIGGV------------------------------- ->tr|A0A1F9YC32|A0A1F9YC32_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFOXYB2_FULL_49_7 GN=A2293_11655 PE=3 SV=1 ---------QRKQSLLGAINAVE-TSARFVYWLSE-ATWGTGRIFDCDGREYK---------------------------- ->tr|A0A1F8ASD3|A0A1F8ASD3_9BACT Uncharacterized protein OS=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_12_FULL_41_24 GN=A3E44_02795 PE=3 SV=1 -------GK--------AYFPVEWVANKLVEILKDDKR--QTETVLYPgdHGFGI---------------------------- ->tr|A1TE18|A1TE18_MYCVP Short-chain dehydrogenase/reductase SDR OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=Mvan_4643 PE=4 SV=1 ----GVVEDYVDNTVLGRAGTAEDIANAVVYLCAPGSSWLTGEVLDINGGAHLKRYP------------------------ ->tr|A0A1J4TX26|A0A1J4TX26_9HELI Uncharacterized protein OS=Helicobacteraceae bacterium CG1_02_36_14 GN=AUJ81_04115 PE=4 SV=1 ----ELYNLYRSISPSKSVLKSSNVVDLAKYLLFKKSKFITGQNIIIDGGISLQW-------------------------- ->tr|A0A1N6J2J6|A0A1N6J2J6_9BURK L-rhamnose 1-dehydrogenase OS=Paraburkholderia phenazinium GN=SAMN05444165_2728 PE=4 SV=1 ----DKRAYFEQRIPLGRLGEPDDVADSAAEIDVLK-------VVHVEAIHDAWTSP------------------------ ->tr|A0A1V6EWP9|A0A1V6EWP9_9BACT Putative ketoacyl reductase OS=Candidatus Cloacimonetes bacterium ADurb.Bin089 GN=actIII PE=4 SV=1 --SGEYlnfrkryFAEYLAQAPTGKLVTKEEIKKVIDLLIDESITTLNGQEIIIGGGI------------------------------ ->tr|A0A1E7YXV5|A0A1E7YXV5_9PROT Oxidoreductase OS=Acidithiobacillus caldus GN=BAE30_05230 PE=4 SV=1 --PEEAMRQRRQE--L-DALHPEDVAQALVYSFAQPPHVLVEEILVRPVKQIV---------------------------- ->tr|A0A1N6CKY3|A0A1N6CKY3_9MYCO Short-chain dehydrogenase OS=Mycobacterium abscessus subsp. abscessus GN=fabG_19 PE=4 SV=1 --SEAELAAITEDLPQQRLIDPTEIAHTCSYLCHPFAKSITGTIQKVNGAWYL---------------------------- ->tr|M5RGJ4|M5RGJ4_9PLAN 3-oxoacyl-(Acyl-carrier protein) reductase OS=Rhodopirellula maiorica SM1 GN=RMSM_04555 PE=4 SV=1 -----WDGRARNQSLMNRWGTPEDVARAIAFVSDPENSFFSGQVVQVNGGWNRNYIHR----------------------- ->tr|Q0CLZ1|Q0CLZ1_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_05293 PE=4 SV=1 -----ARRILDHNCPMGCMGSSDDVANGVVWLSSGASRYVTSHALVIDGGITESTG------------------------- ->tr|T0GTY7|T0GTY7_9SPHN Uncharacterized protein OS=Sphingobium baderi LL03 GN=L485_05485 PE=4 SV=1 ----DLAERIRGALALPRFGQRIDIGNAVAWLCSEAASFVTGTTIDCDGGMRLGNL------------------------- ->tr|A0A1V2IK14|A0A1V2IK14_9ACTN Short-chain dehydrogenase OS=Frankia sp. M16386 GN=BL253_01850 PE=3 SV=1 ----GEhthlvWPRLQAEGtinrVIGKHGgmTVESVADVHIFIATRPR----GQKLDVVRARSY---------------------------- ->tr|B9EBG7|B9EBG7_MACCJ Uncharacterized protein OS=Macrococcus caseolyticus (strain JCSC5402) GN=MCCL_0871 PE=4 SV=1 ---DDVE-SIIEQIPQKKCVQPVEISHFVRALLHQYSHTTTGTVIRINGGWYI---------------------------- ->tr|A8SQL8|A8SQL8_9FIRM Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Coprococcus eutactus ATCC 27759 GN=COPEUT_00529 PE=4 SV=1 ----DAFKANVKMPPMGHFGDVEkEIGRACVALASPDFKYMSGETITLEGAMGQ---------------------------- ->tr|A0A0F4YLI5|A0A0F4YLI5_TALEM 2-(S)-hydroxypropyl-CoM dehydrogenase OS=Rasamsonia emersonii CBS 393.64 GN=T310_7066 PE=4 SV=1 ----RIFENTMEWYPLKRAIEPEDVANAVAFLASPQAAAITGIRLNEYKFVNLTLTDI----------------------- ->tr|A0A1Z5S7Q4|A0A1Z5S7Q4_SORBI Uncharacterized protein OS=Sorghum bicolor GN=SORBI_3001G264100 PE=4 SV=1 ------RDNILSRAPLRRAGEPEEISSIVAFLCMPGSTYtatRSGRACCPGSRagAALPGLKA----------------------- ->tr|A0A1X1YZB1|A0A1X1YZB1_MYCNO Short-chain dehydrogenase OS=Mycobacterium nonchromogenicum GN=AWC18_18520 PE=4 SV=1 -------EWLARSLVQARQMTPEAVADTLAGIF-------AAAIEQPDVSLES---------------------------- ->tr|A0A1H7FNL0|A0A1H7FNL0_STIAU 2-keto-3-deoxy-L-fuconate dehydrogenase OS=Stigmatella aurantiaca GN=SAMN05444354_10195 PE=4 SV=1 ---PGMRASLVANIPAGRTGEGYEAAELALSLATNASNFMAGQVISMAGGWCT---------------------------- ->tr|A0A1U6J1Y6|A0A1U6J1Y6_9MICC 3-oxoacyl-[acyl-carrier protein] reductase OS=Arthrobacter sp. P2b GN=SAMN06272721_12047 PE=4 SV=1 ---PEYMDEIKRMVPMGRFGSPSEVGALIGAVTSGEMQFVSGQVIAFSGAGC----------------------------- ->tr|A0A1G3K7L2|A0A1G3K7L2_9SPHN Uncharacterized protein OS=Sphingopyxis sp. RIFCSPHIGHO2_01_FULL_65_24 GN=A2885_02830 PE=4 SV=1 ----ARTALVGEFHPSRQMVSPEQIADAVAWAAAPGGAHATGLTIPIDGGWSA---------------------------- ->tr|A0A1F9ULZ6|A0A1F9ULZ6_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 GN=A2992_01980 PE=4 SV=1 --SEEQRERVTAEHALGHTTQIEDLTRLVMEVAQ--NTSVSGQIFNIDSRV------------------------------ ->tr|A0A1F9DS51|A0A1F9DS51_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_16_55_12 GN=A2W10_08930 PE=4 SV=1 --------------ARGRLPGPEILGN-GFVLAAQLPMEQSGRLFEYQDGKLV---------------------------- ->tr|A0A0S4QP12|A0A0S4QP12_9ACTN Acetoacetyl-CoA reductase OS=Frankia sp. G2 GN=Ga0074812_10852 PE=4 SV=1 -MPEPIKDAWLDSLPNG-FVDPDDIANAVAFFAAPESAMVTGQLLTVDGGDALNTRSV----------------------- ->tr|A0A235G8G2|A0A235G8G2_9NOCA 3-oxoacyl-[acyl-carrier protein] reductase OS=Rhodococcus sp. OK302 GN=BDB13_3041 PE=4 SV=1 -MPAETRDRVLRNVAMKRLVEVNEVVASVLFLMSSGAGAITGQSLRVDGGAGINTQGL----------------------- ->tr|A0A1U8JLB6|A0A1U8JLB6_GOSHI tropinone reductase homolog At2g29260, chloroplastic-like isoform X2 OS=Gossypium hirsutum GN=LOC107906578 PE=4 SV=1 ---NRSLvikqcpsS-----------------NGSVSWYCESEFAKFQDKLQANDT-------------------------------- ->tr|N1LQL4|N1LQL4_9BACI 3-oxoacyl-[acyl-carrier protein] reductase OS=Bacillus sp. GeD10 GN=EBGED10_37560 PE=4 SV=1 ----NGKNFIKRFIPTKKLVDKNHLGYLLTYLSSDFSTSITGAAITVDRGHSI---------------------------- ->tr|C1H9Z2|C1H9Z2_PARBA 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase OS=Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) GN=PAAG_07721 PE -----FVERRHKAVPMGGMGDSFDVAYSVAFWLLNRRSISLDRRSLWIGELLHPL-------------------------- ->tr|A0A1G0E8G7|A0A1G0E8G7_9GAMM 3-ketoacyl-ACP reductase OS=Gammaproteobacteria bacterium RBG_16_37_9 GN=A2V89_02635 PE=4 SV=1 ---KEYNDWVIDKQCLKTRIHPEHVANLIVFLSGPKSDYITAQNIGIDAGW------------------------------ ->tr|G4TJW2|G4TJW2_SERID Related to 3-oxoacyl-[acyl-carrier-protein] reductase OS=Serendipita indica (strain DSM 11827) GN=PIIN_05541 PE=4 SV=1 --SSDVMNTMKQANPYKKLGDPKDIALAVEGIL-VSGKWLNGSNIRANGGSA----------------------------- ->tr|A0A149QGT3|A0A149QGT3_9BURK Uncharacterized protein OS=Burkholderia megalochromosomata GN=CR51_22955 PE=3 SV=1 ---------RADSVPMRWQG---EGGTLVRTQ-HSLHRMTHDSSLGRYSPWTV---------------------------- ->tr|A0A1C1XMV5|A0A1C1XMV5_9PEZI Uncharacterized protein OS=Diaporthe helianthi GN=DHEL01_06212 PE=4 SV=1 ---------RVEQNLLGTEGTGWDVGYGETDRPGSSSKaeFTRRPNGRASG--SAG--------------------------- ->tr|A0A1U8HVQ0|A0A1U8HVQ0_GOSHI 3-oxoacyl-[acyl-carrier-protein] reductase 4-like OS=Gossypium hirsutum GN=LOC107887677 PE=3 SV=1 -------KRILTTIPFGRYGQPAEEYEVVSYQTSrELNCFIPSKSERTTESVIS---------------------------- ->tr|S3BPQ4|S3BPQ4_9ACTN Uncharacterized protein OS=Streptomyces sp. HPH0547 GN=HMPREF1486_05706 PE=4 SV=1 ---QAVRQRLDARMALPRMAEDGDVAETVAFFASARSRGITGQCLMVNAGELM---------------------------- ->tr|A0A173KZW8|A0A173KZW8_9SPHN 3-oxoacyl-[acyl-carrier-protein] reductase OS=Sphingobium sp. EP60837 GN=EP837_03405 PE=4 SV=1 ---EDVVAGVTKNIPIGIIPPEDDCARAVLMMVSDYSRVVSGAALDVNGGQWM---------------------------- ->tr|A0A0C1RDR3|A0A0C1RDR3_9ACTN Uncharacterized protein OS=marine actinobacterium MedAcidi-G2A GN=MB53_01975 PE=4 SV=1 ---QEEYDNVADEIALRYIPDSEQICGSVVFFASDLSIACTGTSLDVNGGHFM---------------------------- ->tr|A0A1A3PMG4|A0A1A3PMG4_9MYCO Uncharacterized protein OS=Mycobacterium sp. 1245111.1 GN=A5658_07735 PE=4 SV=1 ---ADVRAEYASALALGRIPTGAEYADVAVFLLSELSRAVSGHVLDANGGEYF---------------------------- ->tr|A0A0M3CHM1|A0A0M3CHM1_9SPHI 2-deoxy-D-gluconate 3-dehydrogenase OS=Sphingobacterium sp. IITKGP-BTPF85 GN=L950_0201165 PE=4 SV=1 ---PQLAAEAQNHVPVQALIESEEVAKQICWMCLPENRHLTGSTILMDGGLSLM--------------------------- ->tr|A0A063B258|A0A063B258_9BURK 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Burkholderia sp. lig30 GN=LIG30_4275 PE=4 SV=1 -----HGRFWEAHSTLRRVGSAAEVASAVMFFAQPEAAYINGTCLPVTSALDW---------------------------- ->tr|A0A0N9R355|A0A0N9R355_CEV01 Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR) OS=Chrysochromulina ericina virus GN=ceV_146 PE=4 SV=1 ----LFKYYNNYINPSKRMCHPDEIADLSLYLTSVKADYINGEIIKIDGGEYIKNSG------------------------ ->tr|G3NFB8|G3NFB8_GASAC Uncharacterized protein OS=Gasterosteus aculeatus GN=ABCC6 PE=4 SV=1 ----EFEKAMIGRIPTGRLGTPTEVSNLAAYISSDYATWMSGAENNEFL-------D------------------------ ->tr|A0A062XUG1|A0A062XUG1_9BACT Uncharacterized protein OS=Thermoanaerobaculum aquaticum GN=EG19_12165 PE=4 SV=1 ----AVQALLAKKVPLRRLASTEEVAFLACDLVTDRHPYVTGDCWTVDGGLWLEGFP------------------------ ->tr|A0A1J5TQS9|A0A1J5TQS9_9EURY Uncharacterized protein OS=Marine Group III euryarchaeote CG-Epi3 GN=BEU00_03375 PE=4 SV=1 ----KTAKMFENYIPLGGVTDSNKMAQQVLYLCSSAADVITGDMLIADGGQWLVGNA------------------------ ->tr|E1YM73|E1YM73_9DELT 3-oxoacyl-[acyl-carrier-protein] reductase OS=uncultured Desulfobacterium sp. GN=N47_E47180 PE=3 SV=1 -------------RYDGRIMTTEDAAYPILFFARDESWCINGNCLQAALGGF----------------------------- ->tr|A0A1F8QVL9|A0A1F8QVL9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_57_8 GN=A2147_07685 PE=4 SV=1 --------GQEIKIDMSKLAMPEELAEAVLFLVSSGSDHMSGQNIIFGVPMA----------------------------- ->tr|G3WQX4|G3WQX4_SARHA Uncharacterized protein OS=Sarcophilus harrisii PE=3 SV=1 ---------HRAIIKIKNTKIKRVISSITCFLLSPAAGHIVNAD----CGNTSFPNL------------------------ ->tr|S2EUB1|S2EUB1_9PSED Uncharacterized protein OS=Pseudomonas sp. G5(2012) GN=PG5_48340 PE=4 SV=1 ---PERLEQILKMIPAGTLGDPAFIADSVLLLIADNATSVTGACLDVNGGLFMR--------------------------- ->tr|A0A1K2CCU9|A0A1K2CCU9_9PSED Meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase OS=Pseudomonas sp. NFPP16 GN=SAMN03159327_5 ----DLWARMEGLIPLGRTQIPENIARFCLAVLEN--EDITAQSLSVDGGMNLY--------------------------- ->tr|A0A1C2FWM5|A0A1C2FWM5_9PROT Short-chain dehydrogenase OS=Campylobacter sp. WBE38 GN=A7X81_00945 PE=4 SV=1 ------DLNAIQQFYPLGIGKVENISPLICFLLSKGSSWITGQNFVIDGGGGI---------------------------- ->tr|G9PRR8|G9PRR8_9BACT Uncharacterized protein OS=Synergistes sp. 3_1_syn1 GN=HMPREF1006_02840 PE=4 SV=1 --AGDMRKAIIDQHFFGRIAETDDFLGAAIFLSSDASNYVTGHVLAVDGGWSVSKPW------------------------ ->tr|A0A136J8J5|A0A136J8J5_9PEZI Short chain dehydrogenase OS=Microdochium bolleyi GN=Micbo1qcDRAFT_223091 PE=4 SV=1 --KEAlkpfnkltplgkarpgidtq--EMVSLAEdIGCRPGYLDEVAGIVGIACLPESGWMTGTVMGANGGGAF---------------------------- ->tr|M7SC21|M7SC21_EUTLA Putative 3-ketoacyl-acyl carrier protein reductase protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_9302 PE=4 SV=1 --PGEIIAMQKASTpIENRLGSVKEIADIVAMLAGRDGAWITGQAISASGLGYV---------------------------- ->tr|A0A1X0H2K5|A0A1X0H2K5_9MYCO Oxidoreductase OS=Mycobacterium monacense DSM 44395 GN=BST34_12235 PE=4 SV=1 --PGS-LEKM-NAAtPLRRLGDVADLGRLCVYLSTRDC-YATNAIFHVDGGIES---------------------------- ->tr|B7RT61|B7RT61_9GAMM Oxidoreductase, short chain dehydrogenase/reductase family OS=marine gamma proteobacterium HTCC2148 GN=GPB2148_2902 PE=4 SV=1 ---SAIREAYERQSSMRMFVEPQDVANMALFLSSSLGSAISGQAIGIDGHTEGLAN------------------------- ->tr|A0YBG0|A0YBG0_9GAMM Short chain dehydrogenase OS=marine gamma proteobacterium HTCC2143 GN=GP2143_05550 PE=4 SV=1 ---DTIRDVYQRQTSLRQFVDAQDIADMALYLSSAAGAMISGQSMAIDGHTESLSN------------------------- ->tr|A0A1M6W645|A0A1M6W645_9BRAD NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Bradyrhizobium lablabi GN=SAMN05444159_4463 PE=4 SV ---AEMERTAFSYTSIKDYVTPEQIADQILFMCSPRGKTISGQAISICGDTQMLG-------------------------- ->tr|A0A1W6BHR5|A0A1W6BHR5_9PROT Short-chain dehydrogenase OS=Candidatus Pelagibacter sp. RS40 GN=B8063_05060 PE=4 SV=1 ---KKIEKEFISMASMNCWIYEEDIGKTCSFLMSDDAARVSGQIIAVDGNAI----------------------------- ->tr|A0A0F8A3S3|A0A0F8A3S3_9HYPO Uncharacterized protein OS=Hirsutella minnesotensis 3608 GN=HIM_08255 PE=4 SV=1 ------TQSVSSISPLRTVAAPQDVGKVVAFLSHSDSEWINGQIIPTCGALS----------------------------- ->tr|A0A093V214|A0A093V214_TALMA Versicolorin reductase OS=Talaromyces marneffei PM1 GN=GQ26_0180680 PE=3 SV=1 -------GVAHHYIPGGEKYSPEELQQGSN--------------IDFP--------------------------------- ->tr|A0A158SPX3|A0A158SPX3_9SPHN Putative oxidoreductase with NAD(P)-binding Rossmann-fold domain OS=Novosphingobium sp. KN65.2 GN=yjgI PE=4 SV=1 ----PMAATMHSFMAIKRHVRPAEIAELTAYIAGPHGAMITGSMQTIDGAFG----------------------------- ->tr|A0A1W5CW33|A0A1W5CW33_9LECA Nad-binding protein OS=Umbilicaria pustulata PE=4 SV=1 ----KIEKAMADHNPLRRCALPVDVARVVGFLASQDGEWVNGKFGLHLSSSA----------------------------- ->tr|D2PNP6|D2PNP6_KRIFD Short-chain dehydrogenase/reductase SDR OS=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) GN=Kfla_1804 PE=4 SV=1 --PQAALEHLGQQFTARRLPEAADVAAAIMFLCSARTTATQGEILRVNGGS------------------------------ ->tr|A0A1V2QN86|A0A1V2QN86_9PSEU Short-chain dehydrogenase OS=Saccharothrix sp. ALI-22-I GN=ALI22I_14365 PE=4 SV=1 --PEFVVSALASATPTRRLSDSDDVARIVVFLGSAANGNLTGELIRDGSSA------------------------------ ->tr|A0A1W6YPS3|A0A1W6YPS3_9BORD Uncharacterized protein OS=Bordetella genomosp. 8 GN=CAL12_20790 PE=4 SV=1 --PNL---------ARESLLSPEVMVSPLRWLLSKAADNVTCRRIRANLWD------------------------------ ->tr|A0A0M2NDB5|A0A0M2NDB5_9FIRM Short-chain dehydrogenase/reductase SDR OS=Catabacter hongkongensis GN=CHK_2241 PE=3 SV=1 ----DG--VDVDNMDKSGWQKPIDIAKAVMYFADNDNDQVSGNFLSVRGVNQWI--------------------------- ->tr|A0A158B8T6|A0A158B8T6_9BURK Short-chain dehydrogenase/reductase SDR OS=Burkholderia arationis GN=AWB81_02614 PE=4 SV=1 ----KAFTKAEQRVKFK-LNTAEDLAEYILYLSSRESDQVSGSTLSINGGLSFP--------------------------- ->tr|A0A0D1X5E2|A0A0D1X5E2_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_04986 PE=4 SV=1 --------PMLDATPmGSRLAEPSEIAHAIAFLCERRSGWITGAYYDDYKHASV---------------------------- ->tr|W9AT06|W9AT06_9MYCO Short-chain dehydrogenase/reductase SDR OS=Mycobacterium cosmeticum GN=BN977_03744 PE=4 SV=1 --------ALVTRNHaFGRVGEPTDIGDAICAITARSAGWITAQRIEASGGQSL---------------------------- ->tr|A0A1Y5P2I7|A0A1Y5P2I7_9MICO Putative Short-chain dehydrogenase/reductase SDR OS=uncultured Microbacterium sp. GN=MIPYR_20192 PE=4 SV=1 ------ARgeapaAAGTTLVKGvavREAQLTDVVDVLMFLA-DGPDSVSGVTIRLDGGRVH---------------------------- ->tr|A0A0E3VWU8|A0A0E3VWU8_9BRAD Putative oxidoreductase OS=Bradyrhizobium diazoefficiens GN=NK6_8386 PE=4 SV=1 ----ELNKQVAGMTALGRAGAPDDIGPMIASLLSDDNRWVNAQRIEVSGAWRFSLPGG----------------------- ->tr|A0A1E5L623|A0A1E5L623_9FIRM Uncharacterized protein OS=Firmicutes bacterium MLFW-2 GN=BHU72_02005 PE=4 SV=1 ------REIDHLQHFSQRVGKPDDIASACIYLTHGSNDFILGTNLVIDGGMTKK--------------------------- ->tr|A0A1B6Z4Z8|A0A1B6Z4Z8_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium EhC05 GN=A8B75_01805 PE=4 SV=1 -------------ADAG--MKAKDLATAVFHIVDQGPQGETGRSYFFgfSGTPRNQ--------------------------- ->tr|A3PE87|A3PE87_PROM0 Uncharacterized protein OS=Prochlorococcus marinus (strain MIT 9301) GN=P9301_14391 PE=4 SV=1 -------DQRATLIPVGRLADPKEIAKCCYQICSLDNTFQTLSNITIAGGE------------------------------ ->tr|K0EJ50|K0EJ50_9NOCA 3-oxoacyl-ACP reductase OS=Nocardia brasiliensis ATCC 700358 GN=O3I_007150 PE=4 SV=1 --NPNLLAAMEQMVPLGRGGTPEEAAGAVYLFCIPESDYVSGQTLVCGGGFN----------------------------- ->tr|A0A221VZY9|A0A221VZY9_9PSEU General stress protein 39 OS=Actinoalloteichus hoggarensis GN=ydaD2 PE=4 SV=1 --PAEKVKEFGKQVPFEEAAHPDDLAPSYVFLASNrLSGYYSGEVIAALGGETT---------------------------- ->tr|A0A165RSL1|A0A165RSL1_9HOMO NAD(P)-binding protein OS=Neolentinus lepideus HHB14362 ss-1 GN=NEOLEDRAFT_1067905 PE=4 SV=1 -------SKVGHIIPIGRIGSEEDTVGTIVYLASRAGSYVSGTCIAVSILTWDG--------------------------- ->tr|A0A066VLF9|A0A066VLF9_9BASI NAD(P)-binding protein OS=Tilletiaria anomala UBC 951 GN=K437DRAFT_258369 PE=3 SV=1 -------------GESGDS-----LIFVPVFASSRTRVH---TTFSVHRPLGLA--------------------------- ->tr|A0A1X9NJJ9|A0A1X9NJJ9_9GAMM Uncharacterized protein OS=Oceanicoccus sagamiensis GN=BST96_13600 PE=3 SV=1 -----AKDYTIAHSAIAQVPTPVDIANSLVSVIT-GSDLMTGQIITIDSGYT----------------------------- ->tr|A0A0C1ZC86|A0A0C1ZC86_9DELT Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Enhygromyxa salina GN=DB30_05726 PE=4 SV=1 ---DRVKAVHDRMFPARRMNTMDEVAALVSVLADDAGYWFNSAVIDFTGGQMH---------------------------- ->tr|A0A090PTB4|A0A090PTB4_9FLAO Oxidoreductase OS=Nonlabens ulvanivorans GN=JCM19298_559 PE=4 SV=1 ---EALKEMSLKRNPNHRLTQPVDVANTVYLLALKSLNGLQVMLLKLMVVNHY---------------------------- ->tr|H1XVE2|H1XVE2_9BACT Short-chain dehydrogenase/reductase SDR OS=Caldithrix abyssi DSM 13497 GN=Calab_2088 PE=4 SV=1 ---ETMIDLALSQIPFKRLTQPSDIAKFILALATSDELWATGNVFNVDGGEVI---------------------------- ->tr|A0A0A8UL66|A0A0A8UL66_LEGHA Enoyl-[acyl-carrier-protein] reductase [NADPH] OS=Legionella hackeliae GN=fabL PE=4 SV=1 ---QQLLDEYHAHSLSAEPLTAADVADVIYLLCRPEAKMINAHTLFVDAGYSQ---------------------------- ->tr|A0A0B6ZXM4|A0A0B6ZXM4_9EUPU Uncharacterized protein OS=Arion vulgaris GN=ORF86317 PE=4 SV=1 -------QELGRRAPIRRMGSKTEIAEICLFLVTDMAGLITSSTIEADGAHWLSDGSE----------------------- ->tr|A0A1S2WR18|A0A1S2WR18_MYCMA Short-chain dehydrogenase (Fragment) OS=Mycobacterium malmoense GN=BMG05_01445 PE=4 SV=1 -------IEDlyrrglldeMTMRASLDAAPAAFVAPLYAYLASDLARDVTGQIFVAAGGFVGSLDRP----------------------- ->tr|A0A0A1MJF4|A0A0A1MJF4_9BACI 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Oceanobacillus oncorhynchi GN=fabG_6 PE=4 SV=1 --PSWRKEEYLHSELVDTPVTAKDVAETVVFLLSDKSKHYTGATFDINNGGYL---------------------------- ->tr|A0A023C7R0|A0A023C7R0_9PSED Dehydrogenase OS=Pseudomonas extremaustralis 14-3 substr. 14-3b GN=PE143B_0119735 PE=4 SV=1 --PEYRRAEYARQEILKDPILPSGVAEVIVLLIGESLRHMTGKVIAVDNGAYP---------------------------- ->tr|W5YQ57|W5YQ57_9ALTE Short-chain dehydrogenase OS=Marinobacter salarius GN=AU15_05765 PE=3 SV=1 ---ENQRQQVMSETLLACEGGFDAVVIQLLALLD--NDFITGAQIPVDGGRRLA--------------------------- ->tr|A0A1W6GTJ6|A0A1W6GTJ6_RHIET Short-chain dehydrogenase/reductase SDR family protein OS=Rhizobium etli Brasil 5 GN=Bra5_PD00539 PE=4 SV=1 ------AQDYRDNVAM----PARDIAEVIAFALSRPKRITLNEILV-RPTVQAM--------------------------- ->tr|A0A0E0L8Q4|A0A0E0L8Q4_ORYPU Uncharacterized protein OS=Oryza punctata PE=4 SV=1 ---EERVVAVAGECPMGRIGEPMDVAPVVASSAAMPPGGSTAKSFVsMAATSK----------------------------- ->tr|A0A1B6AHY7|A0A1B6AHY7_9ACTN Putative oxidoreductase OS=Streptomyces sp. NBRC 110611 GN=SSP35_04_01830 PE=4 SV=1 ---GEVSDQIIRAINdgfrTDWLKAPRTVAEWIVSIAEFPSNGPTGQVFNYSRKVL----------------------------- ->tr|A0A1Q7PLW9|A0A1Q7PLW9_9BACT Uncharacterized protein OS=Nitrospirae bacterium 13_1_40CM_2_62_10 GN=AUI21_04375 PE=4 SV=1 -----------DEILRSEKISPYDIAETAVYLATLGPYAVVHQLIVDR-LGA----------------------------- ->tr|A0A0S4MTD2|A0A0S4MTD2_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Candidatus Kryptobacter tengchongensis GN=JGI3_0222 --------------ENADMLHPRHVAPVAAFLLSDLSREINGTMIVVYGTKLFTYHIV----------------------- ->tr|X1R5W9|X1R5W9_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_53840 PE=4 SV=1 ------------------KPDPDFVAPIVVYLTTDTLLAIFTRIRIQPK------RSP----------------------- ->tr|A8XET0|A8XET0_CAEBR Protein CBG12121 OS=Caenorhabditis briggsae GN=CBG12121 PE=3 SV=1 ---------IEICHKhRGNvKNNTEKINVSL------qSSLFR----------------------------------------- ->tr|A0A1Y1UNK0|A0A1Y1UNK0_9TREE Uncharacterized protein OS=Kockovaella imperatae GN=BD324DRAFT_622000 PE=4 SV=1 --TKESLESFGVTTAIGRAGQPVEIATAFVWLASAESSYYTAQCMHLNGGQAY---------------------------- ->tr|V7L3V0|V7L3V0_MYCAV Oxidoreductase OS=Mycobacterium avium subsp. avium 10-9275 GN=O972_13565 PE=4 SV=1 ---AEEQSQWPRWVPVGRMGLPEDQARVILFLVSDCSSFITGHTIPTDGGTIAAGGWF--RSSRR---------------- ->tr|A0A0C5XGA8|A0A0C5XGA8_9SPHN Uncharacterized protein OS=Sphingobium sp. YBL2 GN=TZ53_05845 PE=4 SV=1 ----KSVDTLIANMAMPRLADPVeDVGGAAMFLVSDEACFILGHRVLADGGQHLTAA------------------------- ->tr|G6Y5R4|G6Y5R4_9RHIZ Short-chain dehydrogenase/reductase SDR OS=Mesorhizobium amorphae CCNWGS0123 GN=MEA186_06368 PE=4 SV=1 ----PAaaPRARSASAPTCRQSGwaRRRSSARSAPSCARSTGYLTGQNIPFDGGPYV---------------------------- ->tr|A0A163V4S0|A0A163V4S0_9FLAO Uncharacterized protein OS=Myroides marinus GN=AV926_02100 PE=4 SV=1 -----IDASMIANIPMGRAGYPEDFEAIAVYFCSDASSFHTGDTVILDGADHIKG-------------------------- ->tr|W9BZY3|W9BZY3_9SPHN 2-deoxy-D-gluconate 3-dehydrogenase OS=Blastomonas sp. CACIA14H2 GN=Q27BB25_00100 PE=4 SV=1 -----FQDGCRRRAASGSIGQLQDMEGIAVYLASQQSNFMTGQALVLDGGHTIFPL------------------------- ->tr|A0A1B7NXW9|A0A1B7NXW9_9EURO Uncharacterized protein OS=Emmonsia sp. CAC-2015a GN=ACJ72_04196 PE=3 SV=1 -----------------------NQSGKVLWLTNAaGG-LIVKEGIEifLDaeirhsGGEdATIRA------------------------- ->tr|A0A1I5X943|A0A1I5X943_9ACTN 3-hydroxy acid dehydrogenase / malonic semialdehyde reductase OS=Actinomadura madurae GN=SAMN04489713_12623 PE=3 SV=1 -------KAAAYYDSYPALLDPGDVASAVRFALDQPPGVCCTEITITP-F-PV---------------------------- ->tr|A0A1Q9N1S0|A0A1Q9N1S0_9ARCH 3-oxoacyl-ACP reductase OS=Candidatus Lokiarchaeota archaeon CR_4 GN=RBG13Loki_0315 PE=3 SV=1 -----LTEEQIK---IMNPMDPEELVPFFLFFTTVEGKNVTGLVVDVELVKKVVN-------------------------- ->tr|A0A078HQR1|A0A078HQR1_BRANA BnaC04g14050D protein OS=Brassica napus GN=BnaC04g14050D PE=4 SV=1 ----GYKKSLFSRTPLGRAGEPKEVASLVAFCVYLQLHILLVRPFvLME--------------------------------- ->tr|B9S3E0|B9S3E0_RICCO Tropinone reductase, putative OS=Ricinus communis GN=RCOM_0732870 PE=3 SV=1 ----EVFRGCKSSNPNGKNRRTERGFC-IGSILMPTSSILHNRpdYLC----------------------------------- ->tr|A4XF84|A4XF84_NOVAD Short-chain dehydrogenase/reductase SDR OS=Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC ---EEAEAAISATMALGRVPSDEECARGILVFLSDALSSVTGATLDINAGDYM---------------------------- ->tr|A0A059X0H4|A0A059X0H4_9BACT Short chain dehydrogenase OS=uncultured bacterium PE=4 SV=1 ----EAHARRSAELPLRGAADAEALADGVVAILN--LPSMTGQMLALDGGEHLEWPDR----------------------- ->tr|J3HKX0|J3HKX0_9RHIZ Uncharacterized protein OS=Phyllobacterium sp. YR531 GN=PMI41_04507 PE=3 SV=1 ----QDFNQQVSSLLLERGPDLSEFGRTIRYLWE--TRSITGQMIALDGGQHLAWETA----------------------- ->tr|A0A077FKQ9|A0A077FKQ9_9RICK 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Rickettsiales bacterium Ac37b GN=fabG_3 PE=4 SV=1 ----ENFTASRIHSPLNNAGSIEDIYNAIKFILT--TPSITGELINIDGGKHLSGELN----------------------- ->tr|A0A0P1FFS1|A0A0P1FFS1_9RHOB 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Thalassobacter stenotrophicus GN=fabG_6 PE=4 SV=1 ------AHASDQRFPGEGFANFSEVAAAVRYFSQ--APAVTGQLMSVRVE------------------------------- ->tr|A0A099T9T9|A0A099T9T9_9RHOB Short-chain dehydrogenase OS=Thalassobacter sp. 16PALIMAR09 GN=PM04_08855 PE=4 SV=1 ------AHASDQRFTGEGFANFSEVATAVRYFSQ--APAVTGQLMSVRVE------------------------------- ->tr|F7XU01|F7XU01_MIDMI Short chain dehydrogenase OS=Midichloria mitochondrii (strain IricVA) GN=dltE PE=4 SV=1 ----ENFNKAIQYSLLKKNVSEKNLLDTIYYLIQ--NENLVGNIIFLEN-------------------------------- ->tr|A0A1F6QP30|A0A1F6QP30_9BACT Uncharacterized protein OS=Candidatus Melainabacteria bacterium RIFCSPLOWO2_12_FULL_35_11 GN=A3F80_02505 PE=3 SV=1 ----EYLKHSLDSVPLEKWGSIQNILQSIDFLCE--NDYLTGQCIFAGGGDHLR--------------------------- ->tr|A0A1Q9QA03|A0A1Q9QA03_RHOSU Short-chain dehydrogenase OS=Rhodovulum sulfidophilum GN=BV509_04695 PE=4 SV=1 ----APYAafRASTTPVTGRGSEpkglagCGDAAAALGYLLA--AKAVTGQVICVGDGHFSG--------------------------- ->tr|A0A1Q6DGI8|A0A1Q6DGI8_9CYAN Short-chain dehydrogenase OS=Limnothrix sp. CACIAM 69d GN=BJG00_01380 PE=4 SV=1 ----DYIQWRVQGIPVKQQGSTENISQAVSYILN--NPFVNGQILFVDGGESLTNVGQ----------------------- ->tr|A8P945|A8P945_COPC7 Short chain oxidoreductase OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) GN=CC1G_09549 PE=4 SV=2 ---------KSNVAALGRMASPEDIAGIVSYLAGPDGKNVTGQTSLFIQILST---------------------------- ->tr|F3L577|F3L577_9GAMM Putative oxidoreductase OS=gamma proteobacterium IMCC3088 GN=IMCC3088_8 PE=4 SV=1 ----RFISNLSSQVPTKKVGRGLETAKLAAYLADPDVEHVVGQIIPLAGGWTT---------------------------- ->tr|A0A165USB9|A0A165USB9_9GAMM Short-chain dehydrogenase OS=Halioglobus sp. HI00S01 GN=A3709_00110 PE=4 SV=1 ----RFQERLKREVPLGRLVTAKEDVSLIAYLCSDVADCFVGQVFPMCGGWVG---------------------------- ->tr|A0A104JSN6|A0A104JSN6_BURGA Uncharacterized protein OS=Burkholderia gladioli GN=WJ59_11755 PE=3 SV=1 -LDAAIRERLIAEMPLRRMVSTDEIWLGLRFIIEC--DAFVGRTLAIDGGAS----------------------------- ->tr|A0A1H2KSI7|A0A1H2KSI7_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Gordonia westfalica GN=SAMN04488548_1343637 PE=4 SV ----SSRRLWPRRSRSRsasasptsTHNSPRSSPSTTT--------------------------------------------------- ->tr|S5ZGE2|S5ZGE2_9CREN Uncharacterized protein OS=Thermofilum adornatus GN=N186_09690 PE=3 SV=1 ---SPILQEYLRRIPIARLVEPEEIAKLAYHVVE--NEALTGIVIPIDLGTTIAS-------------------------- ->tr|A0A0K8LUG3|A0A0K8LUG3_PSESF 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Pseudomonas syringae pv. actinidiae GN=fabG1 PE=3 SV=1 -------DELMKMIPAQRMGTPEEVAGAVNFLMSAEAATSPARCWPSMEGCADEACGG----------------------- ->tr|A0A103LL43|A0A103LL43_9BURK Short-chain dehydrogenase OS=Burkholderia sp. FL-7-2-10-S1-D7 GN=WS75_06560 PE=4 SV=1 --------RAAGKTPLGRIAEPVELAEALFFLASEGARPLSGSAVSVDGGASVYGGSV-PCAAAEYDV------------- ->tr|A0A158LZC8|A0A158LZC8_9BORD Putative short chain dehydrogenase OS=Bordetella holmesii CDC-H585-BH GN=L497_2257 PE=4 SV=1 --------RAVAKIPLGRLGDPQDLACALSFLASAEAAVLPADMLCVDGGSSIFGGSQ-AYLPTPHLP------------- ->tr|J4XP15|J4XP15_9FIRM KR domain protein OS=Selenomonas sp. FOBRC6 GN=HMPREF1148_1325 PE=4 SV=1 ---ARSIEMNAQGSAMRRNISLDETCAALEYLLADEASYLQGVNLNLSGGD------------------------------ ->tr|W3YZD9|W3YZD9_9FUSO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Fusobacterium sp. CM21 GN=HMPREF1497_1198 PE=4 SV=1 ---ERLIEAEIEKHPLKRTIKIEEIVETINYILKSKNEFLNGNNILLTGGE------------------------------ ->tr|A0A1V5QC74|A0A1V5QC74_9FIRM Levodione reductase OS=Firmicutes bacterium ADurb.Bin354 GN=lvr PE=4 SV=1 ---PKVREMSLYKN--GKLLVPSDLFETMDEMLSEDFA-ENGTNRKICIS------------------------------- ->tr|B6HFH7|B6HFH7_PENRW Pc20g09760 protein OS=Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) GN=Pc20g09760 PE=4 SV=1 ----DWEQQLKYYGGFPRLAEVQELGGAYVYLLSEAASYTTSIDIPVNGVIGSKCFRV----------------------- ->tr|A0A1Y2EWR7|A0A1Y2EWR7_9BASI Uncharacterized protein OS=Leucosporidium creatinivorum GN=BCR35DRAFT_305997 PE=4 SV=1 ---ASQMENWGVGsvPLHGRVGQPAELGDSYVYLATNN--VTTGSVVHPNLGQHF---------------------------- ->tr|A0A1M7LAC2|A0A1M7LAC2_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga jiangningensis GN=SAMN05444266_110220 -GHEKIQQYLDHLHPLGKMPEGDVIADTAVFLLSNAARFITGCIMPVSGGAELGYRT------------------------ ->tr|A9RGT3|A9RGT3_PHYPA Predicted protein OS=Physcomitrella patens subsp. patens GN=PHYPADRAFT_202254 PE=4 SV=1 ---EQIKERMAKKALLPnRPLTSLDVANAVLFLCSDEAGYISGHNLLLDAARTVGLPIpPGFSHWFEGYSPILK--------- ->tr|Q47PW1|Q47PW1_THEFY Short-chain dehydrogenase/reductase (SDR) family protein OS=Thermobifida fusca (strain YX) GN=Tfu_1472 PE=4 SV=1 ---AGAQEVL-GRTALLgRPIQPADVAAGILYLASDDAAFVTGAVLPVDAGLTGASWPspY-TSGRYAKPVALLE--------- ->tr|A0Z2D1|A0Z2D1_9GAMM Short-chain dehydrogenase/reductase (SDR) family protein OS=marine gamma proteobacterium HTCC2080 GN=MGP2080_11908 PE=4 SV=1 ---DEVEKTLAANSPLPgRAGTALDVANAALWLGSDESGYTSGLTLTTDAGVTTGSMVr---RPNYEDYVPMQR--------- ->tr|A0A1E4I4X5|A0A1E4I4X5_9PSEU Uncharacterized protein OS=Pseudonocardia sp. SCN 72-86 GN=ABS81_10920 PE=4 SV=1 ---DGARAAVLVETPLKdRVGLARDIAEAAVWLLSGAAGYVSGQTLIVDGGLVAGSPPasKGLSNAYSDRAPFLQ--------- ->tr|A0A1S4CTF9|A0A1S4CTF9_TOBAC secoisolariciresinol dehydrogenase-like OS=Nicotiana tabacum GN=LOC107822378 PE=4 SV=1 ----M-GKEGsDVYSTLNgAILTPNDVAETAVFLASDESKCVSGQDFVIDGGFTIENSGfs----LFK----------------- ->tr|A0A1U8LQ86|A0A1U8LQ86_GOSHI tropinone reductase-like 1 OS=Gossypium hirsutum GN=LOC107929762 PE=4 SV=1 ----SIVELKlSNMGNLKgEILKPECVAKAALYLASEEANYVSGVNLLVDGGYSAVNPTmf----KFANLVN------------- ->tr|A0A176VCY6|A0A176VCY6_MARPO Uncharacterized protein OS=Marchantia polymorpha subsp. ruderalis GN=AXG93_592s1000 PE=4 SV=1 ---QASSFFPKMKTSVShKIAGPDSIANAALFLASDDSAYVSGEDLAVDGSHMLQPGDpL--INAYKL---SVA--------- ->tr|A0A176W7E7|A0A176W7E7_MARPO Uncharacterized protein OS=Marchantia polymorpha subsp. ruderalis GN=AXG93_2490s1030 PE=4 SV=1 ---QTLSFFPAMKTGVShPIAGPDSIANAALFLASDDSSFVTGEDLVVDGSHMLCPEDlI--TKIIKS---ALK--------- ->tr|A0A0W1B3G2|A0A0W1B3G2_9BACL Uncharacterized protein OS=Paenibacillus etheri GN=UQ64_08230 PE=4 SV=1 ---DKSYDEYTNMNILGRVGHADEATHTTIYLMT--NKYTTGNTLFPDGGFILR--------------------------- ->tr|Q28S70|Q28S70_JANSC Twin-arginine translocation pathway signal OS=Jannaschia sp. (strain CCS1) GN=Jann_1525 PE=4 SV=1 --NAAQDAMLNPALPLgeTPASEPQAIANTALYLASDLSADVSGAVLDTALGYNANYT------------------------- ->tr|A0A199AWV0|A0A199AWV0_9ACTN 3-ketoacyl-ACP reductase OS=Dietzia sp. 111N12-1 GN=AYO52_15845 PE=4 SV=1 --LEDTAETFSGMNQMpQPWVEPSAIASMAVYLCSDEGAGITGASIPIDLGGSEKFG------------------------- ->tr|K0UWD8|K0UWD8_MYCVA Short-chain dehydrogenase OS=Mycobacterium vaccae ATCC 25954 GN=MVAC_06722 PE=3 SV=1 --PDDLVQAARHYAILrgNKGIESEQVSKTVAFLLSKEASILTGVIMPVDAGHSIMNR------------------------- ->tr|A0A1R4G908|A0A1R4G908_9MICO Short-chain dehydrogenase/reductase SDR OS=Frigoribacterium sp. JB110 GN=CZ774_13060 PE=4 SV=1 --AEDAEAAFAGLNPFgKAWIEPIHVSNAVAWLASDQSYYVSGGQIPVDGAAAVQ--------------------------- ->tr|A0A137SK63|A0A137SK63_9GAMM 3-oxoacyl-[acyl-carrier protein] reductase OS=Moritella sp. JT01 GN=AKG98_4025 PE=4 SV=1 ---EKLMENEVSNIPLQKYASVDDVTGAILALMGPLSNHMTGQNILLDGGFNKCY-------------------------- ->tr|A0A1M3CL17|A0A1M3CL17_9RHIZ Uncharacterized protein (Fragment) OS=Shinella sp. 65-6 GN=BGO06_21980 PE=3 SV=1 -------LNPVSKIPKDKLV-PAvVPASCMAWLCGPGSDGLEEVLLDVRQDLFTRQ-------------------------- ->tr|B4UA19|B4UA19_HYDS0 Dehydrogenase OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=HY04AAS1_1295 PE=4 SV=1 -MEDEEWQKVITNTPLKKEVSLHDIYSVLKLFLE--TTSITGAILPIDGGRHIK--------------------------- ->tr|A0A0B1TEG3|A0A0B1TEG3_OESDE Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Oesophagostomum dentatum GN=OESDEN_06307 PE=4 SV=1 ---EAKLVEEHSYIPYQCIGKPEEIAEAILFLADRKrSNYIVGHQLVIDGGASLQMPVI----------------------- ->tr|E3NW63|E3NW63_CAERE Putative uncharacterized protein OS=Caenorhabditis remanei GN=CRE_28011 PE=4 SV=1 ---YNTMGSLPHCIPVGFCAQPEHIASVIAFLADRKaSEYIVGQTITADGGSTLVLGFH----------------------- ->tr|A0A0F7SLP9|A0A0F7SLP9_PHARH Reductases with broad range of substrate specificities OS=Phaffia rhodozyma PE=4 SV=1 ---KTWVDEWVYRTPLGRMATAQDIGKSVVAMCSDNFMFMTGSDVLVDGGYACL--------------------------- ->tr|A0A0R1LKR7|A0A0R1LKR7_9LACO Uncharacterized protein OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL002634 PE=4 SV=1 ---PKVSASFHDFHPLNRNGQLADIAQAILFLASERASWITGQRWGHISSALT---------------------------- ->tr|A0A0S7HS73|A0A0S7HS73_9TELE DHB14 OS=Poeciliopsis prolifica GN=DHB14 PE=4 SV=1 --AAAAVQAGENAQLMGRMGTEAECGLAALFLAA-DATFCTGIDLLLSGGAELNYGF------------------------ ->tr|Q93P93|Q93P93_9BACT MS138, putative dehydrogenase OS=Microscilla sp. PRE1 PE=4 SV=1 --GEKIIRSIkERVPFENRMTRTDEIANAALFLISEKSSHTTGQHVFVDGGYIHLDRA------------------------ ->tr|A0A1I8H4X7|A0A1I8H4X7_9PLAT Uncharacterized protein OS=Macrostomum lignano PE=4 SV=1 --EGgggdtteDQLARYASDSLFNRLGSIEEIGAACLFLCR-WATYCTGIELPVTAGVELAKPM------------------------ ->sp|O67505|FABI_AQUAE Enoyl-[acyl-carrier-protein] reductase [NADH] FabI OS=Aquifex aeolicus (strain VF5) GN=fabI PE=1 SV=2 ---HLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARAITGEVVHVDNGYHI---------------------------- ->tr|A0A0K8MA34|A0A0K8MA34_PSESF Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Pseudomonas syringae pv. actinidiae GN=PSA5_31545 PE=3 SV=1 ---SGLSDTYAKKLQPTGTPSVNEILNVAIFLISDNSIGVTGDRIFVDGGFHN---------------------------- ->tr|V4L1S7|V4L1S7_9DELT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_03135 PE=3 SV=1 ---SNLLKVASDASPLGHTAELEDIGTMAVEVITN--PSINGVVYLVDCGASA---------------------------- ->tr|A0A0W0RBZ4|A0A0W0RBZ4_9GAMM Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Legionella anisa GN=fabI_3 PE=3 SV=1 ---DNLMEKAANEAPLHQLVTIEAIGETVAFWCRIKPLPLRDKFSMWMAAI-T---------------------------- ->tr|A0A1C7HDZ8|A0A1C7HDZ8_9BURK Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Burkholderiales bacterium YL45 GN=A4V04_04825 PE=3 SV=1 ---GLLMKLAKDLSLLRSLVSTEEVGNLAAFLLSEKSFGITAETVYIDGGFNK---------------------------- ->tr|C4FIX8|C4FIX8_9AQUI Short-chain dehydrogenase/reductase SDR OS=Sulfurihydrogenibium yellowstonense SS-5 GN=SULYE_0518 PE=3 SV=1 ---DIE--KPLQKTLIKKWAGGKEVFKAVKYLI-E-TDFTTGALIPVEGGRLI---------------------------- ->tr|A0A1F9UD83|A0A1F9UD83_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_60_11 GN=A3A86_01395 PE=4 SV=1 ---QKEWDAYrlrsRVKFPVSDKEAVEQFALLALYLC-T-VTLTSGNTYPLDQGHNL---------------------------- ->tr|A0A1D9FUB0|A0A1D9FUB0_9CYAN Glucose dehydrogenase OS=Moorea producens JHB GN=BJP36_02350 PE=3 SV=1 --PQAFMENYaRKFIPLKIPGNTKVVTDSALFLL-E-QDFLTGSTITLDGGQYI---------------------------- ->tr|U5W1L1|U5W1L1_9ACTN Uncharacterized protein OS=Actinoplanes friuliensis DSM 7358 GN=AFR_17935 PE=4 SV=1 ---ERLFASAG-------AVDAEDVAKAYLGFLD--QDHATGNVAVVEGRSAG---------------------------- ->tr|A0A1C4BSE1|A0A1C4BSE1_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga costaii GN=GA0116948_103237 PE=4 SV=1 ---QQSFAYFSSLVHAGRVGRAEEVAAAIYAVLS--NDYINAAIIPVTGGVS----------------------------- ->tr|A0A1C4BB22|A0A1C4BB22_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga costaii GN=GA0116948_10317 PE=4 SV=1 ---KSFLSNHAANLAVGRIGQAIDVAEVIELVTR--CGFITGSIYQVNGGSHLTT-------------------------- ->tr|A0A015WJZ2|A0A015WJZ2_BACFG Short chain dehydrogenase family protein OS=Bacteroides fragilis str. J-143-4 GN=M067_1644 PE=4 SV=1 --PEEIKQNIYKKTAIHRFATIDEIVDAFRFCID--NPFINGSLIEVNGGYNF---------------------------- ->tr|A0A1T4KRM6|A0A1T4KRM6_PORCN 3-oxoacyl-[acyl-carrier protein] reductase OS=Porphyromonas cangingivalis GN=SAMN02745205_00847 PE=4 SV=1 --PTDVRKSIEGKVASHRFASPEEVGQVFKMVAE--NEYFNGDIISLSGGYSY---------------------------- ->tr|N8R639|N8R639_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP-A165 GN=F991_02610 PE=4 SV=1 -VPQERHDLYVNGRAIQRQQLPQDLNGTALYLLSELSSFVTGQNIPVNGGFVFN--------------------------- ->tr|Q6SGK1|Q6SGK1_9BACT Oxidoreductase, short chain dehydrogenase/reductase family OS=uncultured marine bacterium 560 GN=MBMO_EBAC750-16D01.3 PE=4 SV=1 -VSATRHSFYNENRAVPGPQAPEDITETISFLLTKGALTLTGQLLTVNNGFVFS--------------------------- ->tr|C8WQD2|C8WQD2_ALIAD Short-chain dehydrogenase/reductase SDR OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / -----------RTEEGLRPPVGEDVARAVEWFLREDSQEVNGTVLEVTGAREIVAKDS-FPRRPE---------------- ->tr|U1PML0|U1PML0_9EURY Dehydrogenase OS=halophilic archaeon J07HB67 GN=J07HB67_00366 PE=3 SV=1 -----------DTHLPQYACEPETVAHTVEYLLENDYVXXXXXXXvvahtavSFRGPQGRFHSRG-R--------------------- ->tr|A0A1F8JIX3|A0A1F8JIX3_9PROT Enoyl-ACP reductase (Fragment) OS=Caulobacterales bacterium RIFOXYA1_FULL_67_7 GN=A3K57_12950 PE=4 SV=1 ---RGMISQGRAMSAMKEDTSMEGVAGAALWLCSDLGLSTTGEVVHVDAGFHM---------------------------- ->tr|A0A1J8YU79|A0A1J8YU79_9BURK Enoyl-ACP reductase (Fragment) OS=Burkholderia ubonensis GN=BGV55_24425 PE=4 SV=1 ---DLLLNEAVERAPLGELVDIMDVGFSCAYLATPYARRITGNTMFIDGGVSI---------------------------- ->tr|A0A139AD21|A0A139AD21_GONPR NAD(P)-binding protein OS=Gonapodya prolifera JEL478 GN=M427DRAFT_33166 PE=4 SV=1 -YTSPFINEIAKIKPNRRAELLEDEAQGIVIMCMPGMSAMHGHFTMVDGGVNL---------------------------- ->tr|A0A1F8PRJ9|A0A1F8PRJ9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_51_16 GN=A2Y54_06255 PE=4 SV=1 ---SMSS-EYVARRIVDLAKRPRRSLVIPFWflplvtinnIFPGMVDWILGNFFinryhKLDAGAS----------------------------- ->tr|A0A1J6XEU1|A0A1J6XEU1_9MICO Uncharacterized protein OS=Microbacterium sp. AR7-10 GN=BFN01_05580 PE=3 SV=1 ---ADVRAEMVSGTATRSTVSPDDVLASVEYLLDPRNRNITGQDINVSAGAV----------------------------- ->tr|A0A1N7G7V9|A0A1N7G7V9_9EURY 3-oxoacyl-[acyl-carrier protein] reductase OS=Natronorubrum thiooxidans GN=SAMN05421752_11086 PE=3 SV=1 --------AHLPASEREEILQPDVMNDAAVLLAAQGSDGVTGESMAAQEWEQ----------------------------- ->tr|A0A1M6BIS8|A0A1M6BIS8_9FLAO NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Arenitalea lutea GN=SAMN05216261_0751 PE=4 SV=1 --EEELKREAAEALPMGRMLNRFDPVPAVMHFISDDSAMTTGSLMRITGGEYI---------------------------- ->tr|A0A0L9ST48|A0A0L9ST48_9HYPO Uncharacterized protein OS=Ophiocordyceps unilateralis GN=XA68_2342 PE=4 SV=1 -RPAGQMEGFGQKSQLGRPGQPSEVAPSYVFLASKDSELFYGQKLFLLGTSSDLHPTT--LVPR----------------- ->tr|R8BTI6|R8BTI6_TOGMI Putative versicolorin reductase protein OS=Togninia minima (strain UCR-PA7) GN=UCRPA7_1775 PE=4 SV=1 --PMEIIDAGLaKMCPLKRVGTPADIGKAVFTLCSEEGEWINGTSLFSSFSNKI---------------------------- ->tr|A0A1J4RRY9|A0A1J4RRY9_9BACT Uncharacterized protein OS=Candidatus Berkelbacteria bacterium CG1_02_42_45 GN=AUJ40_00475 PE=4 SV=1 ---SGFIKAVAEHAPQGEVTTE-NIADAIVGLVSGMAMHMGGGVFSIDHGHFS---------------------------- ->tr|A0A1E7FW84|A0A1E7FW84_9STRA NAD(P)-binding protein OS=Fragilariopsis cylindrus CCMP1102 GN=FRACYDRAFT_232542 PE=4 SV=1 ---ERMRQDVQIRAPLGNVTSSQVAATVYHVA--AEACGMTGQTIEVDGGYSI---------------------------- ->tr|A0A1F3SY98|A0A1F3SY98_9PROT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Bdellovibrionales bacterium GWB1_55_8 GN=A2X94_05850 PE=3 SV=1 ---RTMLAAAEEKTPLRENISAEDVGEMGAFLCGPGGLHVTGSTLYLDSGAHI---------------------------- ->tr|A0A179FGQ0|A0A179FGQ0_METCM Gluconate 5-dehydrogenase OS=Pochonia chlamydosporia 170 GN=VFPPC_05704 PE=3 SV=1 --NPEGLDAIEERvmsatAAGHRIAETRDIAPIVAFLCEEQSRWITGSVTCANGGYVTV--------------------------- ->tr|A0A0F9X631|A0A0F9X631_TRIHA Glucose and ribitol dehydrogenase OS=Trichoderma harzianum GN=THAR02_07862 PE=3 SV=1 --TTESVKEIS--egTFFRRPAQPAELAPLYVSVVDASSS-VPGDPFLLWF-------------------------------- ->tr|R7C8H5|R7C8H5_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:62 GN=BN737_00737 PE=4 SV=1 ----QLKEVEK-RQYLG-VSDAADIAKTICFLLGEEAKAITGTSMDVSGGFLTS--------------------------- ->tr|A0A0P5JGN2|A0A0P5JGN2_9CRUS Dehydrogenase/reductase sdr family member OS=Daphnia magna PE=4 SV=1 -------TLMYHNCPMRRNGKPEEMAGFAAFFSWHRMTRRTLPEatLLLLeecNPI------------------------------ ->tr|A0A0K0EK38|A0A0K0EK38_STRER Uncharacterized protein OS=Strongyloides stercoralis PE=4 SV=1 --DEV-RGQLEQVIPLGRVAKVYECTSTVEFLCGRGAMFTNGENFVINGGVSVR--------------------------- ->tr|Q3SHP7|Q3SHP7_THIDA Possible oxo-acyl acyl carrier protein dehydrogenase OS=Thiobacillus denitrificans (strain ATCC 25259) GN=Tbd_1886 PE=4 SV=1 -LTAEQIGELASATQFGRLPQLGDVSRLAMFLCSEENTGITGQFIAADLGFS----------------------------- ->tr|A0A094PBW4|A0A094PBW4_9ACTN Uncharacterized protein OS=actinobacterium acIB-AMD-7 GN=GM48_4400 PE=4 SV=1 -LKPEQIENVQGQTPGKKMVTPSDVANATYLLGCEDNTAISGQSLFVDYGFA----------------------------- ->tr|A0A0R2QP35|A0A0R2QP35_9ACTN Dehydrogenase OS=Actinobacteria bacterium BACL4 MAG-121001-bin59 GN=ABR73_03200 PE=4 SV=1 -LKPEQIENVQWQTPGHKMVIPSDVASATYLLGCEENTAISGQSLFVDYGFS----------------------------- ->tr|A0LSD4|A0LSD4_ACIC1 Short-chain dehydrogenase/reductase SDR OS=Acidothermus cellulolyticus (strain ATCC 43068 / 11B) GN=Acel_0571 PE=4 SV=1 --DASTMAFIARKQALtGGILAARHVTELAVELCSARTTALTGQLIAVDGGWSVL--------------------------- ->tr|A0A1F9ZPE3|A0A1F9ZPE3_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_07615 PE=4 SV=1 --DEDILNYMDYKQPIyASKHklgNPLSVAKAATFLAAKESDFITGIILPVDGGWTAQ--------------------------- ->tr|A0A0S4P922|A0A0S4P922_9BURK Short-chain dehydrogenase/reductase SDR OS=Janthinobacterium sp. CG23_2 GN=BN2497_12435 PE=4 SV=1 -LDPKLRESYRRYSALGRTGTCAEAARGLRWLALENT-YLNGAQFPLTGGL------------------------------ ->tr|A0A1F8XCZ5|A0A1F8XCZ5_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium GWA2_65_63 GN=A2X90_11270 PE=4 SV=1 --FPEERWERLRakKRRGRGIGTPEGVARAVLRFARARQ-YNS---------------------------------------- ->tr|K0NFV3|K0NFV3_DESTT FabG: short-chain dehydrogenase/reductase family protein OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=fabG PE=4 SV=1 -LTTDEKQSLIDHILLNRTGCVEDVVKACLFIVKD-APYMTGSILRLDGGYVLA--------------------------- ->tr|S3CS81|S3CS81_GLAL2 NAD(P)-binding Rossmann-fold containing protein OS=Glarea lozoyensis (strain ATCC 20868 / MF5171) GN=GLAREA_09661 PE=4 SV=1 --PQSKIDNNIANSVLKRLASVEDVANMILCISNS--SSQTGTNTVIEAGRTL---------------------------- ->tr|A0A127EPU8|A0A127EPU8_9RHIZ Short-chain dehydrogenase/reductase SDR OS=Rhodoplanes sp. Z2-YC6860 GN=RHPLAN_08260 PE=4 SV=1 --GREGVEKQAATTPLKIVAEADDVALAIIAGITHL-RLTTGSTIVVDSGRHL---------------------------- ->tr|A0A072P9X7|A0A072P9X7_9EURO Alcohol dehydrogenase OS=Exophiala aquamarina CBS 119918 GN=A1O9_11580 PE=4 SV=1 --SAERLQIAQQKSSLKRFATVEACIHCVQAVAEN--KSMTGINSVLDAGFLL---------------------------- ->tr|L7IGN4|L7IGN4_MAGOY Uncharacterized protein OS=Magnaporthe oryzae (strain Y34) GN=OOU_Y34scaffold00215g14 PE=4 SV=1 -----VQESNIARSKLKRVVTPEVRIKPPTWAPLS---------------------------------------------- ->tr|A0A0J0XH69|A0A0J0XH69_9TREE Putative short-chain dehydrogenase OS=Cutaneotrichosporon oleaginosus GN=CC85DRAFT_287485 PE=4 SV=1 --SEAQVKMSTDAALLKKVSDVPDVAAAYIMLMEN--GSITGEILEISAGLGH---------------------------- ->tr|A0A1K1Y2T4|A0A1K1Y2T4_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Olsenella sp. kh2p3 GN=SAMN04487823_10975 PE=4 SV=1 --------------AAGRLATSLEMAWPIVFVNSAGASFVSGLELNVDYADTQMKALK----------------------- ->tr|M5AW56|M5AW56_PSEPU Putative short-chain dehydrogenase/reductase SDR OS=Pseudomonas putida PE=3 SV=1 ---ASHDAATKADIPLGgKFGDVDkDLAPVMVFLASDASHFISRPDVPGRRWAYCGAM------------------------- ->tr|A0A0G4NY39|A0A0G4NY39_PENCA Short-chain dehydrogenase/reductase SDR OS=Penicillium camemberti FM 013 GN=PCAMFM013_S002g000764 PE=3 SV=1 ---AGHDVFMNDRICLGeKFGDVEiDLVPVLAFLVSDASCWITGQLVPVNGGLSLTLV------------------------- ->tr|A0A193FHB9|A0A193FHB9_9BORD Uncharacterized protein OS=Bordetella bronchialis GN=BAU06_10380 PE=4 SV=1 --PPGHIEANRHAIPMGREATAREVAQVIVFLASRLSTFMTGTEVAVDGGLSTSGVAW-----MRRAFQQALAGPVPDVRR ->tr|A0A178J534|A0A178J534_9VIBR Uncharacterized protein OS=Vibrio europaeus GN=AZ468_24475 PE=4 SV=1 -----FIDTIESAIPLNeI-CGQHDIVHGVRFLASDSNTALTGQNININGGWLM---------------------------- ->tr|A0A1Y1INL0|A0A1Y1INL0_KLEFL 3-ketoacyl-ACP reductase OS=Klebsormidium flaccidum GN=KFL_009580010 PE=3 SV=1 ---ESAK-LVQRAVPARrYGDTETDLMGALLLLVSeKASRYIVGVTIPVDGGHSLYT-------------------------- ->tr|A0A1I5QYS3|A0A1I5QYS3_9PSED Uncharacterized protein OS=Pseudomonas composti GN=SAMN05216601_113123 PE=4 SV=1 --NTQLNALVAGNTALDRTSLTISE-------RGEGGRWVNGQRIEASGCMFL---------------------------- ->tr|A0A077REA8|A0A077REA8_9BASI Conserved hypothetcial protein OS=Melanopsichium pennsylvanicum 4 PE=4 SV=1 ---KQVLQSRGDKLLTGRVGQPEDLANVYIYLTK--DKNITAQIIVSDGGDS----------------------------- ->tr|A0A0L8IN25|A0A0L8IN25_PSESX Short chain dehydrogenase OS=Pseudomonas syringae pv. aceris GN=ALO91_102840 PE=4 SV=1 ----EGYLRMIELSPAGRGGTPDEVGALAALLMGPEGTFITGSDFLMDGGVTASYWYG-DLAPA----------------- ->tr|B7CA69|B7CA69_9FIRM Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Holdemanella biformis DSM 3989 GN=EUBIFOR_01090 PE=3 SV=1 -------DLSLDYSPSKRYAAPEEIANLATVLVSGMGRMIVGDTIYATGGAGILT-------------------------- ->tr|R7K386|R7K386_9CLOT Oxidoreductase short chain dehydrogenase/reductase family protein OS=Clostridium sp. CAG:277 GN=BN584_00918 PE=3 SV=1 -------TLYTDCIPAKRFATPSEIGQLAVIMVSDMCNLVVGDTFYISGGSGTTK-------------------------- ->tr|S0KBP1|S0KBP1_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_03227 PE=3 SV=1 -------SIESFENPTGRLVTPVEIGEWAVYMVSAIGQYAVGTVMHLTGGNGIFQ-------------------------- ->tr|A0A0J8YZB5|A0A0J8YZB5_9FIRM 3-oxoacyl-[acyl-carrier-protein] reductase OS=Coprobacillus sp. 8_1_38FAA GN=HMPREF0979_01847 PE=3 SV=1 -------DISCNAQPNKRYIDPIEKSQIATMLVSGIGNSIVGDSIYVSGGNGTFY-------------------------- ->tr|A0A1G9INT1|A0A1G9INT1_STREI 3-oxoacyl-[acyl-carrier protein] reductase OS=Streptococcus equinus GN=SAMN05216400_0265 PE=4 SV=1 -------NLWR-DCSSGRVFLPEEVAEVACFLLSGASKCISGEVIHCNAANHRKV-------------------------- ->tr|V7F7U3|V7F7U3_9RHIZ Short-chain dehydrogenase OS=Mesorhizobium sp. LSHC420B00 GN=X759_35305 PE=4 SV=1 -LDECMQRHLRRHQLLPRVGRPEDVAALVAFLLSDDAAFITGQVVCIDGGMLTHVPTYADGGNSRAARPSGDTAEADAAPR ->tr|A0A024IYV0|A0A024IYV0_RHIRD Short-chain dehydrogenase/reductase SDR OS=Rhizobium radiobacter GN=BN949_03342 PE=4 SV=1 ---EPAYEYWGKLCLVQRPATVEEQAHAALFLLD--NTNMTGNTLFSDGGYSLR--------------------------- ->tr|V5HE32|V5HE32_IXORI Putative mitochondrial/plastidial beta-ketoacyl-acp reductase OS=Ixodes ricinus PE=2 SV=1 -TPEKVRKGIIEEIPMKRIATPLEMSEVIVFMCGPRSTYMVGADRPGVRRDVS---------------------------- ->tr|R6XYA7|R6XYA7_9CLOT Putative 3-oxoacyl-[acyl-carrier-protein] reductase OS=Clostridium sp. CAG:433 GN=BN654_00547 PE=3 SV=1 -MNPEFLDSELKRIGQEKLFTVEDVSKQIINIIKDEQ-IKSGMIIELED-------------------------------- ->tr|R7M1Y9|R7M1Y9_9CLOT Putative 3-oxoacyl-[acyl-carrier-protein] reductase OS=Clostridium sp. CAG:914 GN=BN809_00189 PE=4 SV=1 -IDKTFLDNELKRIGQTRLIEVNELINTISEIIN---NFESGSCYRIDI-------------------------------- ->tr|R6B0M5|R6B0M5_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:533 GN=BN698_00783 PE=3 SV=1 -MDEEY------KKSLGVFLKPEEVAKVVYDISVDE--GVSDAVIRVGD-------------------------------- ->tr|A0A1B8HGR3|A0A1B8HGR3_9GAMM Uncharacterized protein OS=Morganella psychrotolerans GN=AYY16_02360 PE=4 SV=1 --SGLNKDLINLVSPADKVGTVKDIIDSIRFLLT--SDYINGTIMPVDGGYSAGNW------------------------- ->tr|A0A085G814|A0A085G814_9GAMM 3-oxoacyl-[acyl-carrier protein] reductase OS=Ewingella americana ATCC 33852 GN=GEAM_2642 PE=4 SV=1 --SGGDGVFLRALSPAGRTGSTQDIVDAVFYLVD--ARFTSGVVLPIDGGATAGVW------------------------- ->tr|A0A0B3AUA3|A0A0B3AUA3_9ARCH Clavaldehyde dehydrogenase OS=archaeon GW2011_AR17 GN=QT08_C0012G0023 PE=3 SV=1 ---------------KWKMLRSEDIAEYIIALASRDILRIV-yVRILNVWRRFY---------------------------- ->tr|A5UTC3|A5UTC3_ROSS1 Short-chain dehydrogenase/reductase SDR OS=Roseiflexus sp. (strain RS-1) GN=RoseRS_1481 PE=3 SV=1 -----------GEEFRRRLMTAADVAEVILWVCTLPPTVRVDELPIMPRQIDM---------------------------- ->tr|A0A1G3BNZ2|A0A1G3BNZ2_9BACT Uncharacterized protein OS=Planctomycetes bacterium RIFCSPLOWO2_02_FULL_50_16 GN=A3I59_07175 PE=4 SV=1 -----------PEHEPEGLLTPEEVAQKILSLSDPDDGTRSGTSVHIHKRY------------------------------ ->tr|A0A1J4RR02|A0A1J4RR02_9CHLR Uncharacterized protein OS=Anaerolineae bacterium CG1_02_58_13 GN=AUJ21_11140 PE=4 SV=1 -----------ALRRYFHSMTSEEVAERVIELAKRPRRAVILpwYYKIAIWADWY---------------------------- ->tr|A0A1F9PEU7|A0A1F9PEU7_9DELT Uncharacterized protein OS=Desulfobacterales bacterium RIFOXYA12_FULL_46_15 GN=A2277_08525 PE=4 SV=1 -----------APLLDEEMIQPEDIMKTIAWVLELAPNTCVREITLECFKSIA---------------------------- ->tr|A0A1G3R3L1|A0A1G3R3L1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_16_67_19 GN=A2V99_02175 PE=4 SV=1 -----------SLDPKTRLLEPEDLALMVQYLIETPGHFSIWNMDLVALEQSF---------------------------- ->tr|A0A1F8TG15|A0A1F8TG15_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_19FT_COMBO_62_14 GN=A2Z37_10775 PE=3 SV=1 -----------WRTPVSMVLSPEHVAESIIGLTRRPRATLVLppYYRLVIWLDFI---------------------------- ->tr|A0A238VH60|A0A238VH60_9BACT NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Hymenobacter mucosus GN=SAMN06269173_101645 PE=4 SV=1 -----------GQEPDPHKMQPEDIAAAIVHALEAPQTVMISELQMRPTQPK----------------------------- ->tr|A0A1E4ZLS9|A0A1E4ZLS9_9BACT Uncharacterized protein OS=PVC group bacterium (ex Bugula neritina AB1) GN=AB834_03890 PE=3 SV=1 -LTKDSVEKYRLENTLKDLASMESICQSVYDIS--FWPQVSGQTFVLDSR------------------------------- ->tr|A0A1F6RNL5|A0A1F6RNL5_9BACT Uncharacterized protein OS=Candidatus Moranbacteria bacterium RIFCSPHIGHO2_01_FULL_55_24 GN=A2808_02535 PE=4 SV=1 -VDKDVQEDILHPKDIADLTLH---------LSGTPSRVI------FDEI------------------------------- ->tr|K2E6A9|K2E6A9_9ZZZZ 3-ketoacyl-(Acyl-carrier-protein) reductase OS=groundwater metagenome GN=fabG PE=4 SV=1 -NDDKLWKGFADHNPMKRVATVEDVADAVIPLINDPHKFLNGNFLFVNGGNHL---------------------------- ->tr|A0A1A2SLN5|A0A1A2SLN5_9MYCO Short-chain dehydrogenase OS=Mycobacterium colombiense GN=A5685_19820 PE=4 SV=1 -IYTHLasNPDWNMRVALGRGGCPVEAGELIAFLLGERAAFMTGAAINIDGGTDF---------------------------- ->tr|R0G198|R0G198_9BURK Short-chain dehydrogenase/reductase SDR OS=Herbaspirillum frisingense GSF30 GN=HFRIS_021031 PE=4 SV=1 ---AGLKEKVAAAFPARRVGRAEDIGHAALFLMT--NPYVTGTVVEVSGGETLVDS------------------------- ->tr|C9LJR4|C9LJR4_9BACT Uncharacterized protein OS=Alloprevotella tannerae ATCC 51259 GN=GCWU000325_02478 PE=4 SV=1 -FPQELKKVFSKNSPLERIVEPDEIAKAVFFMATDASSAITGETIPVTAGFEISTGQ------------------------ ->tr|A0A0B7KEH3|A0A0B7KEH3_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000012036_1 PE=4 SV=1 -FTNTELELAS-qv-LEFHRLAQPAEVAMHYVEVADPANTYMSGEVIAIAGA------------------------------- ->tr|A0A0C9S1T7|A0A0C9S1T7_9SPER TSA: Wollemia nobilis Ref_Wollemi_Transcript_22637_1458 transcribed RNA sequence OS=Wollemia nobilis PE=4 SV=1 ---DKVEQSVKDIVPLQRWLDTKnDLSAIVLYLVSDDSSFMTGTVIFVDGGQSIVRPR------------------------ ->tr|A0A0U1LXV9|A0A0U1LXV9_9EURO Carbonyl reductase, putative OS=Talaromyces islandicus GN=PISL3812_04944 PE=4 SV=1 -VPQETKDIWKDKIPLGFVSLPPLKPFsnkltsedgRVRVTNSKVHSYIsllTQQAIQLGQTY------------------------------ ->tr|W6WR65|W6WR65_9BURK 3-oxoacyl-(Acyl-carrier-protein) reductase OS=Burkholderia sp. BT03 GN=PMI06_005612 PE=3 SV=1 ----ETHKALGSLHPVGHMGEMSDIVNAVLYLDS--ASSPAvtvrSPVLHSLDLARRGRVAH----------------------- ->tr|A0A069PLA1|A0A069PLA1_9BURK 3-oxoacyl-ACP reductase OS=Caballeronia glathei GN=BG61_23560 PE=4 SV=1 ----------HRAASEGTRETIREIVDAVLDLTD--TDSMTGKVIPVGGLLADAA-------------------------- ->tr|A0A1X1Y2A4|A0A1X1Y2A4_9MYCO 3-oxoacyl-ACP reductase OS=Mycobacterium kubicae GN=AWC13_26435 PE=4 SV=1 ----VDaCAAYARMHPQNRIGGVADVVHGALYLEM--SPFVTGEILHIDGGQSAGHTNP----------------------- ->tr|K0S486|K0S486_THAOC Uncharacterized protein OS=Thalassiosira oceanica GN=THAOC_24515 PE=4 SV=1 --DPNVVDMWTPHLPVGRLGKVDDIADATLMLAT--NEWMSGSIVTVDGGMTGRANMPFRPRPARQSAPEV---------- ->tr|B7G461|B7G461_PHATC Predicted protein OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=PHATRDRAFT_47583 PE=4 SV=1 --DPSNVQAWADRIPLGKLGTVEHVAQACLPLLT--NDWITGAIWQVDGGMMARSNMPTRPRPLKFGGIC----------- ->tr|A0A0G0Z911|A0A0G0Z911_9BACT Uncharacterized protein OS=Parcubacteria group bacterium GW2011_GWA2_42_18 GN=UV08_C0007G0017 PE=4 SV=1 -ISEAEKKMCESRTMINRYVADDEIALAAIGILE--NDAITGQIITVDGGLSLQKLER----------------------- ->tr|A0A0G0TQ71|A0A0G0TQ71_9BACT 3-oxoacyl-ACP reductase OS=Candidatus Levybacteria bacterium GW2011_GWA2_40_8 GN=UU21_C0001G0025 PE=4 SV=1 -PDKKGQEELGQVHLIKRMIQPDEIAECIVFLAK--SDVICGEVFTVDGGMSLVTLG------------------------ ->tr|A0A1Q3P4J3|A0A1Q3P4J3_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium 33-17 GN=BGO27_07210 PE=4 SV=1 -PDNFMFRA--TDNVLGNIIDVAQVISTIDFLIN--NKAITGEIIRVDSGKHLQMKSD----------------------- ->tr|N1Q1E2|N1Q1E2_DOTSN Uncharacterized protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=DOTSEDRAFT_40319 PE=4 SV=1 --DNKVVERALATVPLQKVALPEDVARQVAVMASPsLSGHVNGVNLQVGQYL------------------------------ ->tr|A0A0C9U8K4|A0A0C9U8K4_9HOMO Unplaced genomic scaffold SPHSTscaffold_344, whole genome shotgun sequence OS=Sphaerobolus stellatus SS14 GN=M422DRAFT_193561 P --HALILILFlRNRTPLKKFARPEHVTHQIVILASPiLSGHISREVVVVAGGM------------------------------ ->tr|E4PIC6|E4PIC6_MARAH Short-chain dehydrogenase/reductase SDR OS=Marinobacter adhaerens (strain HP15) GN=HP15_67 PE=4 SV=1 --SEEYKEKSLNKSVLGIEPGPEVVYQGVRYLMD--NIYVTGECLNLDGGRHL---------------------------- ->tr|K0Q512|K0Q512_9RHIZ Putative short-chain type dehydrogenase/reductase OS=Rhizobium mesoamericanum STM3625 GN=BN77_p270036 PE=4 SV=1 -LDERLQRQLHRHQLLAHVGRPEDVAALVVFLLSDDAAFITGQVVCIDGGMLAHLPTYADGGNNPAERPVD---------- ->tr|W3X0E3|W3X0E3_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_08680 PE=4 SV=1 ---RDIPDWHQNGAPFQRLGLPKDLTPMVCYLLSDASASTTGADMLITELQLDYT-------------------------- ->tr|A0A0D3RJC1|A0A0D3RJC1_STRAD Ketoacyl-(Acyl-carrier-protein) reductase OS=Streptomyces alboniger GN=pamM PE=4 SV=1 --NPAFLEATNRLVPTGRMSEATEVAALVCYLISPAAAGLTGTQLRVDGGGHCLAGLP-NLAPPEHTLRGRNPAVTPCVPR ->tr|U2RM60|U2RM60_9ACTN KR domain protein OS=Propionibacterium acidifaciens F0233 GN=HMPREF0682_2684 PE=4 SV=1 --DETFLQSWLARIPMGRPGTTTEIVPLASYLLSSRSQSVTGQVIALDGGFSL-PNLP-SVQLHRrTSA------------- ->tr|A0A1C6QX72|A0A1C6QX72_9ACTN 3-oxoacyl-[acyl-carrier protein] reductase OS=Streptomyces GN=YUWDRAFT_05734 PE=4 SV=1 --GPDHRRGWISRIPAGRVGRPPEVASVLGHLLSGSAARVTGAVLRVDGGFGL-GDVA-PLRPGFpEPVAVDSVEEAR---- ->tr|A0A229T8B2|A0A229T8B2_9PSEU Short-chain dehydrogenase OS=Amycolatopsis sp. KNN50.9b GN=CF166_24080 PE=4 SV=1 --DPAFVSVSMRRVPVAHPSEPEDLAAVIAYLASPASAMISGARLRVCGGLATLGPLP-ALTGSSRHAVRATATAVAR--- ->tr|A0A1X7E0S0|A0A1X7E0S0_9RHIZ NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Rhizobium oryzae GN=SAMN02982989_3261 PE=4 SV=1 ---KTMFDNAADKLPVNLVGLPEHIAVQITAFQL--NPYITGSIVYVDGGGAL---------------------------- ->tr|A0A0J8RC22|A0A0J8RC22_COCIT 2-deoxy-D-gluconate 3-dehydrogenase OS=Coccidioides immitis H538.4 GN=CIHG_00229 PE=3 SV=1 --DAARNDGIMARIPAGSGVNLRISRAWLCFLPAKPVRMSPGRLSVSTvDGW------------------------------ ->tr|A0A0J5P2U7|A0A0J5P2U7_9PAST Short-chain dehydrogenase OS=Muribacter muris GN=RO21_11030 PE=4 SV=1 --EGEQRMKIIADIEAGIPLGhfgePIDVAYGILYLASNESRYLTGIELTIDGGILAGSEAKPK--------------------- ->tr|A0A137XH17|A0A137XH17_OCHAN Uncharacterized protein OS=Ochrobactrum anthropi GN=AYJ56_17440 PE=3 SV=1 -------EKLTAGLAMGEWVPPQEIGALIGFLATGTCRHMTGCTIDFNGASYIR--------------------------- ->tr|B3Q3G3|B3Q3G3_RHIE6 Putative 3-oxoacyl-[acyl-carrier protein] reductase protein OS=Rhizobium etli (strain CIAT 652) GN=RHECIAT_PC0000643 PE=3 SV=1 -------EAAVGDIPIGEMAEPGEIAETGGLPASSVTG--IGQRRDIRRQwrqlhqveQFQR--------------------------- ->tr|E4TV38|E4TV38_MARTH Short-chain dehydrogenase/reductase SDR OS=Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B- -------GFALDDIALTKLTEPEDVSPTIAMLMSGLMDHATGTTIDINAGSYVH--------------------------- ->tr|N4VBM4|N4VBM4_COLOR Short-chain dehydrogenase reductase sdr OS=Colletotrichum orbiculare (strain 104-T / ATCC 96160 / CBS 514.97 / LARS 414 / MAFF ---AAARKVLEAGKSThNGYGRPEDIADVAGLIVSDSAHWINGSVVAANGG------------------------------- ->tr|A0A120A3X6|A0A120A3X6_BACSE Putative 3-oxoacyl-(Acyl-carrier-protein) reductase, FabG-like OS=Bacteroides stercoris GN=fabG_1 PE=4 SV=1 --TPEGYKAMVAQEPIGRLGKVEEMVSSMLWLCSEGAGFMVGHALVMDSGQTVG--------------------------- ->tr|R5EGV3|R5EGV3_9GAMM Uncharacterized protein OS=Succinatimonas sp. CAG:777 GN=BN779_01816 PE=4 SV=1 -------YLTEGYQPYG-LIPTHVISEAICFLLGPNAKYYSGSCVKIPAGVCC---------------------------- ->tr|A0A0N1H5M1|A0A0N1H5M1_9EURO Putative NADP-dependent mannitol dehydrogenase OS=Phialophora attae GN=AB675_7294 PE=4 SV=1 ---ENVKDEAHRMAVLGRQGDVKELKAVYLWLASSAGGFATGSDVLVDGGYTLHEWGP-SEGHDR---------------- ->tr|A0A1L9SQV1|A0A1L9SQV1_9EURO Uncharacterized protein OS=Penicilliopsis zonata CBS 506.65 GN=ASPZODRAFT_129952 PE=4 SV=1 ---PNeWQKKWLDMIPANRMADPYELKGVSSAA--FFCLPFASKEIlLTSQGFCLPCLRR-FELyHRR---------------- ->tr|D6U054|D6U054_9CHLR Short-chain dehydrogenase/reductase SDR OS=Ktedonobacter racemifer DSM 44963 GN=Krac_2981 PE=4 SV=1 --TEDRLKQISTTVPLSRLGKPEEVASVVAFLASSDASYITGEEIHIDGGRGSVISQH-FLGNRERHSQGVSL-------- ->tr|A0A0F9SVM1|A0A0F9SVM1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0426100 PE=4 SV=1 --EEDELRHILSAQAIPELLTPADLAGTFLFLGSPAAAAMTGQALVVSRGEVMH--------------------------- ->tr|A0A0A1GEA1|A0A0A1GEA1_9PSED 3-hydroxybutyrate dehydrogenase OS=Pseudomonas sp. MT-1 GN=MT1_2310 PE=4 SV=1 --EAEELVAVLAAQAIPELLTPADLSGTFLFLGSPLAAALTGQALSVSHGEVMH--------------------------- ->tr|A0A063TS84|A0A063TS84_BORBO KR domain protein OS=Bordetella bronchiseptica OSU553 GN=L533_1591 PE=4 SV=1 --EPAMRAEVLQHVSLHRTVPMADIARTALFLACGTGRSITGQCMNICAGVQTL--------------------------- ->tr|A8LED9|A8LED9_FRASN Short-chain dehydrogenase/reductase SDR OS=Frankia sp. (strain EAN1pec) GN=Franean1_3203 PE=4 SV=1 ----DDVEHFTASQLTGRLIDPAEVAETIAFCCSVAGGVLTGSVVSAEGGFR----------------------------- ->tr|A0A010QZ38|A0A010QZ38_9PEZI L-xylulose reductase OS=Colletotrichum fioriniae PJ7 GN=CFIO01_09197 PE=3 SV=1 --PKELMEHWLSMIPGGRVCHPAELRGPELMIERCDRWRI-HIAVAYDQAGGSPTDWM----------------------- ->tr|F9X1G6|F9X1G6_ZYMTI Uncharacterized protein OS=Zymoseptoria tritici (strain CBS 115943 / IPO323) GN=MYCGRDRAFT_31902 PE=4 SV=1 --PKEWRDHWSLLVPAGRNADPAELKGAYVFLASDASSYMTGKSHPVLLVKAALTNRR----------------------- ->tr|A0A074Y486|A0A074Y486_9PEZI Uncharacterized protein OS=Aureobasidium subglaciale EXF-2481 GN=AUEXF2481DRAFT_43042 PE=4 SV=1 --PAELMDKWLSMVPCGRIAQPAELKAVCRKCMRSE----DRTKMIAALRVPCK--------------------------- ->tr|A0A133KEM5|A0A133KEM5_BACCO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Bacillus coagulans GN=HMPREF3213_03135 PE=4 SV=1 --LKPLIEQWNKMAPLHRMGKPEELQSICVYLAGDTSTFTTGADFIVDGAFTCI--------------------------- ->tr|S4MHF4|S4MHF4_9ACTN Putative Bacilysin biosynthesis oxidoreductase BacC OS=Streptomyces afghaniensis 772 GN=STAFG_6967 PE=3 SV=1 --RPPNAPPWRPASPPAAWSAPARSRAPSPTWRAPCPAPPraprsPSTAACRACGCA----------------------------- ->tr|L1KS66|L1KS66_9ACTN Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Streptomyces ipomoeae 91-03 GN=STRIP9103_00354 PE=4 SV=1 ---PSRIPRARSPVPPQVLVSPST-AACTVYGSGPASDLPhe----------------------------------------- ->tr|A0A060NRR7|A0A060NRR7_9BURK Dehydrogenase with different specificities related to short-chain alcohol dehydrogenase OS=Comamonadaceae bacterium A1 GN=SRAA_ -QSPENFHLASRINLRRQPIAPQDVAKTCLFMAE--TPSICGTTLCVDNGQHLVPLNQ----------------------- ->tr|A0A0N1LNK7|A0A0N1LNK7_9PROT Uncharacterized protein OS=alpha proteobacterium AAP38 GN=IP70_06530 PE=4 SV=1 -QTEEDFQTAHATAPLGRGSTPADISALVAYCLE--APLMSGRTITVDGGQHLQPRNR----------------------- ->tr|A0A0H4VFM2|A0A0H4VFM2_9SPHN Putative oxidoreductase protein OS=Erythrobacter atlanticus GN=CP97_07450 PE=4 SV=1 -QSAQEADRSHTLNLLQRRTGVAEVADAALFLAE--GPLASGQNIHVDSGQHLLDQTR----------------------- ->tr|A0A0L6T8K6|A0A0L6T8K6_9BURK Uncharacterized protein OS=Methylibium sp. NZG GN=AD742_12230 PE=4 SV=1 -IDDARLQRMAALSLTGRTVQPTDVADAVAFALG--NAALTGSTLMIDAGYHLQPMAR----------------------- ->tr|W0AJI2|W0AJI2_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_28610 PE=4 SV=1 -QSRDNFEKAHRMTALGTGVTVDDLVAALRFLIA--TPTITGQTIAIDAGQRFLGLPR----------------------- ->tr|A0A1G0Z1D5|A0A1G0Z1D5_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_44_16 GN=A2017_05610 PE=4 SV=1 -MENSKMEKTLKSVPMAKAVSMDDLTNACLFLAE--NNSITGQILYVDGGQHLHHGYN----------------------- ->tr|A0A1S6FFR3|A0A1S6FFR3_9SPHN Short-chain dehydrogenase OS=Sphingomonas sp. LM7 GN=BXU08_01235 PE=4 SV=1 -QTPEEFSEHARQNLLQRPVALDDIAATVEHLLT--CRSITGQNVFVDCGQRFLQRDG----------------------- ->tr|E4N4U3|E4N4U3_KITSK Putative fatty acid synthase OS=Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-60 --SDALRATCAAAAPLGGVGHEDDLARLVGFLASPQSRWISGQCLLADGGLSVGRAMLT---------------------- ->tr|A0A0B5EGM8|A0A0B5EGM8_STRA4 Beta-ketoacyl synthase OS=Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) GN=SLNWT_011 -----------------AAATPRALAQLTAFLLGDTAAALDGHLLTLATPAPAHEPATA---------------------- ->tr|A0A1V4A9M7|A0A1V4A9M7_9ACTN Uncharacterized protein OS=Streptomyces tsukubensis GN=B1H18_13335 PE=3 SV=1 --PAAVPGGGADTSELMrRTLSTPDAAKLIVHLLHEDTGFITGQTIVADGGISIGGMQGMRLNSR----------------- ->tr|E3RFT6|E3RFT6_PYRTT Putative uncharacterized protein OS=Pyrenophora teres f. teres (strain 0-1) GN=PTT_06605 PE=4 SV=1 -------VFGTGQVPQGRMGGFNDVGGMILFLVGKGGAYVNGAVQLSDGGRVGVFPGT----------------------- ->tr|A0A178DVJ8|A0A178DVJ8_9PLEO NAD-P-binding protein OS=Pyrenochaeta sp. DS3sAY3a GN=IQ07DRAFT_142507 PE=4 SV=1 --PEQYYVEAQATTALAEPVPVRAVAMAILSLASHNFsSHIHGQIVNVDGG------------------------------- ->tr|A0A090MI52|A0A090MI52_9HYPO WGS project CBMI000000000 data, contig CS3069_c001773 OS=Fusarium sp. FIESC_5 CS3069 GN=BN850_0067940 PE=4 SV=1 --ESgTvKWVESESTVAQKKAVDIDGIAKMCLVLASEKWsPSVTGQNVRLNGG------------------------------- ->tr|A0A1L7W069|A0A1L7W069_GIBIN Uncharacterized protein OS=Fusarium proliferatum ET1 GN=FPRO_11496 PE=4 SV=1 --SSgAlRWIESEATVAQKKAVDVEGIAKMCLVLASEKWsPSVTGQNVRLNGG------------------------------- ->tr|A0A126Z048|A0A126Z048_9MICO Uncharacterized protein OS=Frondihabitans sp. PAMC 28766 GN=AX769_09260 PE=4 SV=1 --SPEVSEQLRHLQPVsGGAQAADSVAKVVCWTLSDEALDLSGAVIPADGGWTL---------------------------- ->tr|A0A0R1JWM4|A0A0R1JWM4_9LACO Short chain dehydrogenase OS=Lactobacillus namurensis DSM 19117 GN=FD30_GL000359 PE=3 SV=1 ----------------KRFAsgpqVIARLADRAALSRRPKTRYHA-------GAGS----------------------------- ->tr|H3FJZ4|H3FJZ4_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00112153 PE=4 SV=1 ---EEAVAAAATTVPVGRCGVLEELGNISAFICSDYGNFINGAIIDIDGAQQHFNH------------------------- ->tr|A0A1X7NNJ0|A0A1X7NNJ0_AZOLI NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Azospirillum lipoferum GN=SAMN02982994_1390 PE=4 SV ---VKVGATEADQIPLRRHGRMDELRNLLVFLMADGCDYLTGQTIGIDGGHHLAAP------------------------- ->tr|V4YJZ2|V4YJZ2_9PROT 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Betaproteobacteria bacterium MOLA814 GN=fabG_3 PE=3 SV=1 -LSPKALAAKQEALLKPKVLEVEEIMHAINFFASPLARNISCQTVYFGG-------------------------------- ->tr|A7H4M9|A7H4M9_CAMJD NAD dependent epimerase/dehydratase family protein OS=Campylobacter jejuni subsp. doylei (strain ATCC BAA-1458 / RM4099 / 269.9 -VPQNKLDILLNQQAIKRFGEFEDVLNVIEFFLDEKSGFITSQVVYLGG-------------------------------- ->tr|C4RL58|C4RL58_9ACTN Short-chain dehydrogenase/reductase SDR OS=Micromonospora sp. ATCC 39149 GN=MCAG_05299 PE=4 SV=1 -VPQRKIDELVARQAIQRICTMPDIVGPVEFLIGQQSAFVTGETIFLGG-------------------------------- ->tr|A0A0M9DXE3|A0A0M9DXE3_9DELT Oxidoreductase OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_009834 PE=3 SV=1 -VNlsDEIMNDILEHTISKAWLEMEDVWHTIDFLISKKSEKISGQTIFLGG-------------------------------- ->tr|A0A1F9HB44|A0A1F9HB44_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_40_36 GN=A3I69_03160 PE=4 SV=1 -FSLEQRKKIIAGSGFQKNVTTQDVFFTLNFILSQNSHAMTGQVITLGG-------------------------------- ->tr|N8VHE4|N8VHE4_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP 102159 GN=F974_00835 PE=4 SV=1 -IPFERQKRLKEATLNHKFCQVQEIANTALWLADKAPNCLSGEVFDLNNGVNYR--------------------------- ->tr|A0A1P8KKD4|A0A1P8KKD4_9PROT Short-chain dehydrogenase OS=Arcobacter sp. LPB0137 GN=LPB137_03815 PE=4 SV=1 -NSEQRKKEFKKTVSSGRFAQPEEVAKAIVWLATECPVYINGITLDINDCSYAR--------------------------- ->tr|I0H4L0|I0H4L0_ACTM4 Putative short-chain dehydrogenase OS=Actinoplanes missouriensis (strain ATCC 14538 / DSM 43046 / CBS 188.64 / JCM 3121 / NCIMB ----HMYAAGYYYNALPtPMLEPDAVARVAVFLNSELAEFVTGQHFFVDAGHSVLPRS------------------------ ->tr|A0A1A9I2H8|A0A1A9I2H8_9BACT Uncharacterized protein OS=Niabella sp. BS26 GN=A8C56_13590 PE=4 SV=1 ----DEVAAHLaKSDALGlPWLKAEDVAPAVAFLTSSAADKITGAVYDVAGGTSPVYTS------------------------ ->tr|K6WGP0|K6WGP0_9ACTN Putative oxidoreductase OS=Gordonia rhizosphera NBRC 16068 GN=GORHZ_126_00430 PE=3 SV=1 ----ETSDEVVktTQHTLPvGSFAPQHISDALLYLVSDGAQMISGTALDVTAGMSTQWSA------------------------ ->tr|W9ARI5|W9ARI5_9MYCO Carveol dehydrogenase OS=Mycobacterium cosmeticum GN=BN977_00291 PE=3 SV=1 ----DAEEVFAKGRPRPGLLDPQDVADTVLYLVTDRVKCRSGESITLANGMD----------------------------- ->tr|A0A1E4I7A5|A0A1E4I7A5_9PSEU 3-ketoacyl-ACP reductase OS=Pseudonocardia sp. SCN 72-86 GN=ABS81_08000 PE=4 SV=1 ----HPNLGGMFTNILPlEQAEPRDISDTVLFLASDESRFFTAHELSPDAGVTEY--------------------------- ->tr|A0A1H5PYY3|A0A1H5PYY3_9ACTN SDR family mycofactocin-dependent oxidoreductase OS=Jiangella alba GN=SAMN04488561_6935 PE=4 SV=1 ----DYLAATRQWHVLRnrPALHPSAVADVVSWLCGHDARFITGTAVPVDAGHLVLPGF------------------------ ->tr|A0A0A0DXB3|A0A0A0DXB3_9SPIO Uncharacterized protein OS=Spirochaeta odontotermitis GN=JY97_11445 PE=4 SV=1 ----EAKEQFFQGHMIQdPEVTPEDIGRAVLWLASEDSRCIHGNMITVDSGWTAQAP------------------------- ->tr|A0A1Q8KNI6|A0A1Q8KNI6_9PSEU Short-chain dehydrogenase/reductase SDR OS=Pseudonocardia sp. Ae707_Ps1 GN=Ae707Ps1_2356 PE=4 SV=1 ----EVHKR-WLHDQLLaEVLSIGEITGALMWLLGDDARRVTGHCLAVDGGALAR--------------------------- ->tr|X7V9X0|X7V9X0_9MYCO (-)-trans-carveol dehydrogenase OS=Mycobacterium sp. MAC_080597_8934 GN=L841_2804 PE=3 SV=1 ------------------YVEPADISNAILFLVSTTRATSPGSHYRSTVAPSS---------------------------- ->tr|V5II76|V5II76_IXORI Putative mitochondrial/plastidial beta-ketoacyl-acp reductase OS=Ixodes ricinus PE=2 SV=1 ---QTLLQRLQYMIPLRRIADPLEISETIVFYVQPEKPYLHDRIYKLyvAGGKAC---------------------------- ->tr|A0A1A5WMN2|A0A1A5WMN2_9GAMM Dehydrogenase OS=Aeromonas dhakensis GN=A9196_03980 PE=4 SV=1 --REAMLGRAAASLPAGRHGRAEDLAAGYLLAID--NPFMTGATIDIDGGALIN--------------------------- ->tr|A0A0S4J1Y0|A0A0S4J1Y0_BODSA Short chain dehydrogenase, putative (Fragment) OS=Bodo saltans GN=BSAL_75060 PE=4 SV=1 ----GFLAT--mPSYALNRMATPDETANIFLFLASKQGLLINGTAQRADAACI----------------------------- ->tr|X8DJ73|X8DJ73_MYCXE Short chain dehydrogenase family protein OS=Mycobacterium xenopi 4042 GN=I553_1865 PE=4 SV=1 -MPEKLRDALIKAIPFRRLARPEEVAARCCSSLRMPrRSSLAR--WSVSAA--ALPWPDDKLPPIRSTEP------------ ->tr|A0A0B3BVL9|A0A0B3BVL9_9PSED 3-ketoacyl-ACP reductase OS=Pseudomonas flexibilis GN=fabG PE=4 SV=1 -IPLTIREAGRRMNALNQGGLPQDVAEAVAWLAQPSSGAVTGQVLRVCGQSLLGA-------------------------- ->tr|A0A158CH51|A0A158CH51_9BURK Acetyacetyl-CoA reductase OS=Burkholderia glebae GN=AWB82_05416 PE=4 SV=1 ---TLHQHQIVVTIPVRCLGRPDEVGLIVAWLASKESGFSAGADFSLNGGLHMG--------------------------- ->tr|I5C544|I5C544_9BACT Short-chain dehydrogenase/reductase sdr OS=Nitritalea halalkaliphila LW7 GN=A3SI_08461 PE=4 SV=1 ----EVKKNFEQMIPLGAMAPTRRWPSSppSCFLTAVNSLLVR---------------------------------------- ->tr|A0A1Q8JDP5|A0A1Q8JDP5_9PSEU 3-oxoacyl-[acyl-carrier protein] reductase OS=Pseudonocardia sp. Ae356_Ps1 GN=Ae356Ps1_0219 PE=3 SV=1 ----DVAGGIEdilergepgecwfvqpgrEPAPYGFRgvpspkgaGKPPEIGWQ----DH----------------------------------------------- ->tr|A0A0M2PER6|A0A0M2PER6_9BACI Short-chain dehydrogenase OS=Bacillus sp. SA1-12 GN=WQ54_23975 PE=4 SV=1 -----LYDSYQFKVPNAILGSHDDLAQCALYLSSDEAIYMNGADIRLDGGFMLHYVDKKMKKAD----------------- ->tr|C5EVB2|C5EVB2_9FIRM Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_05668 PE=4 SV=1 -----LYEGYQYKIPSGTVGSASDTAQLCGFLLDSRCRYVNGTEIRMDGGLLLHYIDEKANHRG----------------- ->tr|K9HAW4|K9HAW4_AGABB Uncharacterized protein OS=Agaricus bisporus var. bisporus (strain H97 / ATCC MYA-4626 / FGSC 10389) GN=AGABI2DRAFT_77756 PE=3 -MSNP-SEELRKRIPIGRFGRPQEVASIVELLVT--NAYMTNKVGTETSASLRYPTL------------------------ ->tr|A0A0D2H079|A0A0D2H079_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.5, whole genome shotgun sequence OS=Rhinocladiella ma -LPGS--QELAARVPVGRLGKPEEIAETVIWIVR--TAYVHNKVVAVDGGMFIQ--------------------------- ->tr|A0A0B7KK65|A0A0B7KK65_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000013617_1 PE=4 SV=1 ---PDLHQKWVSLILQGKMGKPEDLMGPHILVVLLKSLHYWG--------------------------------------- ->tr|F2NQD1|F2NQD1_MARHT Short-chain dehydrogenase/reductase SDR OS=Marinithermus hydrothermalis (strain DSM 14884 / JCM 11576 / T1) GN=Marky_0912 PE=3 --------EFHQRLPIGRPAPRTRSRAWCWSWRATWRRTCTGP-------------------------------------- ->tr|A0A1E5V287|A0A1E5V287_9POAL Uncharacterized protein OS=Dichanthelium oligosanthes GN=BAE44_0019709 PE=4 SV=1 ---TQLNEMINNCKAK-T-ANDDDVANAAVYLASDYGKSVTGQNLVLNNALYP---------------------------- ->tr|A0A1N6KJP9|A0A1N6KJP9_9BRAD 3-oxoacyl-[acyl-carrier protein] reductase OS=Bradyrhizobium erythrophlei GN=SAMN05443247_08379 PE=4 SV=1 --------SLAKHIPLGRLGQATDLAPMALAVLSNsRELRSSSMAACR---------------------------------- ->tr|A0A1S1HIV9|A0A1S1HIV9_9SPHN Diacetyl reductase (S)-acetoin forming OS=Sphingomonas haloaromaticamans GN=budC PE=4 SV=1 -YQPEVAAGAARANPMHRMGDPErDIGGVVLFLAGEDARYLTGNTLFVDGGahIRRRPYQRRRLGPRHLRRGLIRQAAGAASPR ->tr|A0A0K2QVI1|A0A0K2QVI1_PORUM Xanthoxin dehydrogenase OS=Porphyra umbilicalis GN=PuXanDH PE=2 SV=1 -LPL---DKIKAMIPMGRLGEAGRGGGHGHLPRhRPGRGVRDGAHV------------------------------------ ->tr|A0A066WE84|A0A066WE84_9HOMO Uncharacterized protein (Fragment) OS=Rhizoctonia solani AG-8 WAC10335 GN=RSAG8_02438 PE=4 SV=1 ---HSNGDINSDGGGSRYLDSTQDLAGVLLFLASTVGARVTGARIESEATETHNITRW----------------------- ->tr|R7D989|R7D989_9FIRM Oxidoreductase short chain dehydrogenase/reductase family protein OS=Ruminococcus obeum CAG:39 GN=BN639_01634 PE=4 SV=1 --DKVLWNEIMEQTPLKRWMTVEEAADWAYFMTV-TNRFCTGQNILIDGL------------------------------- ->tr|Q5BC99|Q5BC99_EMENI Putative oxidoreductase [Source:UniProtKB/TrEMBLAcc:Q8X186] OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / ---PEVEETWMRGALLGRLGVPDDFKAPSGLNEWSSKSAS----------------------------------------- ->tr|A0A1S1TNU9|A0A1S1TNU9_9RHIZ Short chain dehydrogenase OS=Mesorhizobium sp. ORS3428 GN=ORS3428_06565 PE=4 SV=1 --DDDDFGKQVEGLILKRGPQLPEFGATIRYLWQ--ARSVTGQMIALDGGQHLAWQTP----------------------- ->tr|A0A1Z9I990|A0A1Z9I990_9EURY Uncharacterized protein OS=Euryarchaeota archaeon TMED164 GN=CBD24_00615 PE=4 SV=1 --DEDSLKAVQSQSPLGFGPSANDVSESVVFLAN--SPSITGQTIFVDSGERFRQMRK----------------------- ->tr|A0A1Z9S3C5|A0A1Z9S3C5_9EURY Uncharacterized protein OS=Euryarchaeota archaeon TMED255 GN=CBE15_06745 PE=4 SV=1 --TDRGFALAQSQSPLGYGPTPEDIAQTVILYFS--VPSLTGQVITVDSGEHMMNRSR----------------------- ->tr|Q9XE46|Q9XE46_ARATH NAD(P)-binding Rossmann-fold superfamily protein OS=Arabidopsis thaliana GN=At2g07640 PE=4 SV=1 --PEEIENKTREYMPLYKLGEKWDIAMAALYLSCDSGKYMSGLTMVVDGGLCLSKPRHLAKEWRRGLGPGE---------- ->tr|U1QUH0|U1QUH0_9EURY Dehydrogenase OS=halophilic archaeon J07HX64 GN=J07HX64_02697 PE=4 SV=1 ---EVIEDVMLGQARTKEMMTPADVANLFVFGLSGYANHLNGADLLFDGGYTHTY-------------------------- ->tr|L9YQE2|L9YQE2_9EURY Uncharacterized protein OS=Natrinema gari JCM 14663 GN=C486_17929 PE=4 SV=1 ---EVVENVMLEHTRVTEMMEPYEVANLFVMGCSQHSKHLNGGDMTHDGGMSLTY-------------------------- ->tr|F0Z8T3|F0Z8T3_DICPU Putative uncharacterized protein OS=Dictyostelium purpureum GN=DICPUDRAFT_91189 PE=4 SV=1 ---SVAKDILLKHTVDGEFTTVEDVAEVAVNFSAIPNKCLTGQSLLVSHGWIME--------------------------- ->tr|A0A212SA62|A0A212SA62_RHOAC Enoyl-(Acyl carrier protein) reductase OS=Rhodoblastus acidophilus GN=SAMN06265338_11825 PE=4 SV=1 -MKTRFIAEHRPSSLLRRLAGVEEVANMEVYLCSAQASATNGAWV--RGGV------------------------------ ->tr|A0A146VKF3|A0A146VKF3_FUNHE L-xylulose reductase (Fragment) OS=Fundulus heteroclitus PE=3 SV=1 --DPEKARSMTSRIPLGRFAGQKQQVMCLLSVCHQITHVFSQRpvFISADAKMSSR--------------------------- ->tr|L9KZR1|L9KZR1_TUPCH L-xylulose reductase OS=Tupaia chinensis GN=TREES_T100007383 PE=3 SV=1 --DPHKAKAMLDRIPLGRFAGELGRSPAQSYIRVGGLRMYP---------------------------------------- ->tr|A4BTD2|A4BTD2_9GAMM 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Nitrococcus mobilis Nb-231 GN=NB231_07687 PE=4 SV=1 -MPAKVLDKIKAKIPLGRLADPNEIGHSVVYLFE--NDYFNGRVLEAGGGCVCREAPTASLIP------------------ ->tr|A0A0D1EBZ8|A0A0D1EBZ8_9RHOB Putative short-chain type dehydrogenase/reductase OS=Jannaschia aquimarina GN=jaqu_38910 PE=3 SV=1 --FDAVSEMIAQSTPIGiGHLEPEEVAASVMFFTTDATKNMTGEVLDVSYGSAATSV------------------------- ->tr|A0A165RX03|A0A165RX03_9RHOB (-)-trans-carveol dehydrogenase OS=Pseudovibrio sp. W74 GN=limC PE=3 SV=1 --WDMVEEFTRRQHPLPvGVLEPRDIGKTVKFLCSEDAALVSGEAIDVSAGRTANWP------------------------- ->tr|L8F581|L8F581_MYCSM 3-oxoacyl-[acyl-carrier-protein] reductase OS=Mycobacterium smegmatis MKD8 GN=D806_6906 PE=3 SV=1 --KEDLQGAKYWSTLRDvGLLPPQAMSEAVLWLASDESRWTTGLEMLVEGGHMLMPG------------------------- ->tr|Q0RX62|Q0RX62_RHOJR Short-chain dehydrogenase OS=Rhodococcus jostii (strain RHA1) GN=RHA1_ro09080 PE=3 SV=1 --IDDVAEEFRRYQPQGvPWIPPQAITDALMFLVSDGAKHMTGETLSVAAGQNANGA------------------------- ->tr|M3VHC7|M3VHC7_9ACTN Putative oxidoreductase OS=Gordonia malaquae NBRC 108250 GN=GM1_045_00110 PE=3 SV=1 --RDDVAPVFASLHAQPvPFIEPEEVTRVVLFLADELTSHITGTVVPIDAGAAARVS------------------------- ->tr|A0A1A1YF41|A0A1A1YF41_9MYCO 3-ketoacyl-ACP reductase OS=Mycobacterium sp. ACS1612 GN=A5724_02415 PE=4 SV=1 --PDDLVRRMMKGNPIPaPWIEPEDVSRGLMYLVTDR-GVITGSVLEIGLGGSARIH------------------------- ->tr|A0A1H5ID94|A0A1H5ID94_9NOCA SDR family mycofactocin-dependent oxidoreductase OS=Rhodococcus jostii GN=SAMN04490220_7601 PE=4 SV=1 --ADDVEPVFRSLHAQPvAWLDAFEITRVVLFFAAEGSAHISGTVLPVDAGNAARVT------------------------- ->tr|A0A1M3BLU6|A0A1M3BLU6_9ACTN 3-ketoacyl-ACP reductase OS=Solirubrobacterales bacterium 70-9 GN=BGO11_17895 PE=3 SV=1 --LEDALPAFQSVNVLPvPYAETDDISDAVLFLASEQARYITGATLSAAIGVNAKNI------------------------- ->tr|A0A1G1LQK7|A0A1G1LQK7_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium GWA2_47_8 GN=A2Z88_04640 PE=4 SV=1 --PEVVQKFIEEKLPRKIMGKAEEIIPLILFLCSQAASMMGGCLVPIDAGEGKAF-------------------------- ->tr|A0A1F2U7L7|A0A1F2U7L7_9BACT Uncharacterized protein OS=Acidobacteria bacterium RIFCSPLOWO2_02_FULL_59_13 GN=A3H27_13170 PE=4 SV=1 --PEAYQKFIEERLPRKVMGDASELIPMLALLCSEDASMMGGCLVPIDAGEGRAY-------------------------- ->tr|A0A1I8AFD8|A0A1I8AFD8_9BILA Uncharacterized protein OS=Steinernema glaseri PE=4 SV=1 --TPENRSRFLAGIPLGRFCTPKDVAAAALYLASDEAEFITGTCIEITGtlvelveaGCDLILTTGGTGPARRDVTPEATLDAGT---- ->tr|A0A117NKX9|A0A117NKX9_9EURO Uncharacterized protein OS=Penicillium freii GN=ACN42_g10410 PE=3 SV=1 ---PAVKDAMLDSEGINNLHFSSIDESRLlhSWKENDIAYCWRGLLLP----------------------------------- ->tr|A0A212D9W3|A0A212D9W3_CEREH DCXR OS=Cervus elaphus hippelaphus GN=Celaphus_00001494 PE=4 SV=1 --DPEFSQKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSESGILVDAgatpprpaappsglqghqatllhaldhapdaihahsqtctprptvwshlhdttrqrptslqphtcptpptprtrphsstpnmwvpgdpvppapthcvvhsplkvrssrnimdlrlagrralvtgagkGI------------------------------ ->tr|U7PL39|U7PL39_SPOS1 Uncharacterized protein OS=Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) GN=HMPREF1624_08292 PE=4 SV=1 --PETEGYDHPAFIPARRFGTDTDMAGTILYLASPAGGFCNGLTLVFDGGRLPVAT------------------------- ->tr|A0A0J8RWA2|A0A0J8RWA2_COCIT Short chain dehydrogenase/reductase family protein OS=Coccidioides immitis H538.4 GN=CIHG_06187 PE=4 SV=1 --------DPSKLIPEGRAGADTDMAGIVLFLAITLRDVdlfRLPKISLDDAKEPSlhlTSP------------------------- ->tr|A0A0C4F9K6|A0A0C4F9K6_PUCT1 Uncharacterized protein OS=Puccinia triticina (isolate 1-1 / race 1 (BBBD)) PE=3 SV=1 ---SVLKDTMGLDIPEGRAGIDKEIAAAVLYLASKNQQYTSGSVILADGGVLNLMP------------------------- ->tr|A0A1R3RFI8|A0A1R3RFI8_ASPC5 Uncharacterized protein OS=Aspergillus carbonarius (strain ITEM 5010) GN=ASPCADRAFT_209822 PE=4 SV=1 --GVSDGSFPSQMVPLTRAGSEQEFAGMVLWMASASGAYINGNITVTDGGRLSTVP------------------------- ->tr|A0A0B6AEF4|A0A0B6AEF4_BACAH Uncharacterized protein OS=Bacillus thuringiensis (strain Al Hakam) GN=BG07_2917 PE=4 SV=1 ---EDKMYQLAGTLSLNRISTPEDSAEAVLFQLT--QESITGQIYTIDNRQTL---------------------------- ->tr|G8WPK4|G8WPK4_STREN Short-chain dehydrogenase/reductase SDR OS=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) GN=SCATT_28150 PE=4 SV=1 --DPVAYERFTAEFPGRELVRPEEIADVIAFLLSDQARGVTGVNLPVDRGQNAPTPQG----------------------- ->tr|M5BJH1|M5BJH1_THACB Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IB / isolate 7/3/14) GN=BN14_01457 PE=4 SV=1 ---PELADKWASMNPLGRLGRPDELRGVVAWLASDASTFSYLLAVAITLGDGLTSN------------------------- ->tr|A0A1H2JRD2|A0A1H2JRD2_9ACTN NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Gordonia westfalica GN=SAMN04488548_1342420 PE=4 SV -ASPGVTEWISNSTPLGRMAERGGDRRGGripaqrPRLLRHRRDRAGRrrrrRLSRTAPGASKGYAEL-IHSSV----------------- ->tr|A0A024M4S1|A0A024M4S1_9MYCO Short chain dehydrogenase OS=Mycobacterium farcinogenes GN=BN975_04048 PE=4 SV=1 --DADSIAAISRNVPLGRLAKPADIGWATAFFVVFGRLlyqrcvvggarWRGAAALPVHHD------------------------------- ->tr|G8G907|G8G907_EPICO Peroxisomal trans-2-enoyl-CoA reductase (Fragment) OS=Epinephelus coioides PE=2 SV=1 -IGPTIFKTAIPLSPAKRLGVPEEISSAVCFLLSPAASFISGATLRVDAGQSLYHSMW--EIPDHSAWPEAPEGENLD--- ->tr|A0A0B0I3Y1|A0A0B0I3Y1_9BACL Levodione reductase OS=Paenibacillus sp. P1XP2 GN=lvr_1 PE=3 SV=1 ------------PAAVggaGHAGKRSRSRSLFGFGRIDPYHRHPGVHRR-SGVASPVRRLQ----PSR---------------- ->tr|A0A194VK60|A0A194VK60_9PEZI Dehydrogenase/reductase SDR family member 4 OS=Valsa mali GN=VM1G_11182 PE=4 SV=1 ---EEVMAKVAKELSVGFVASPEDVAEAYLYFIR--ADYANGATVVIGKWVFL---------------------------- ->tr|A0A1F8B9Q4|A0A1F8B9Q4_9BACT Uncharacterized protein OS=Candidatus Woesebacteria bacterium RIFCSPLOWO2_01_FULL_39_10b GN=A2892_01885 PE=3 SV=1 ----PQ--------YIGEVIDPKEIGKYAVYLCSEEANDITGKVFVLKKGKEPYEGY------------------------ ->tr|M7A8F8|M7A8F8_9ACTN Short-chain dehydrogenase OS=Gordonia sp. NB4-1Y GN=ISGA_3549 PE=3 SV=1 ---GEYTRYFISMMDDYPVATLDDISDAVLYLMSPQSRAITGMQMPIDMGNS----------------------------- ->tr|A4T1S3|A4T1S3_MYCGI Short-chain dehydrogenase/reductase SDR OS=Mycobacterium gilvum (strain PYR-GCK) GN=Mflv_5072 PE=3 SV=1 ---PTFLHSFAPMPFkpvardgkpgLQEFMTVEEVSDVVAWLAGDSSATISGSQIAVDRGTM----------------------------- ->tr|A0A0Q5QDN2|A0A0Q5QDN2_9ACTN Short-chain dehydrogenase OS=Williamsia sp. Leaf354 GN=ASG12_17890 PE=3 SV=1 ---EKYQPHFAPILNEPFFSTRDEVTSLVMYLCSDDARTITASTFSMDQGSV----------------------------- ->tr|A0A1B5ZF45|A0A1B5ZF45_9NOCA Putative NAD-dependent oxidoreductase OS=Rhodococcus sp. Br-6 GN=Br6_01820 PE=4 SV=1 ---PRYIDNYKWPLAGLSKCSVDDVSEVVLYLASDRSRTVTGSQMSLDLGIT----------------------------- ->tr|A0A0D2HH82|A0A0D2HH82_XYLBA Unplaced genomic scaffold supercont1.15, whole genome shotgun sequence OS=Cladophialophora bantiana CBS 173.52 GN=Z519_09572 PE -LPKEWTeALYARATAERRITEVHDVTDVVSWLAGPDSKLVNGNFVP----------------------------------- ->tr|F6HNU5|F6HNU5_VITVI Uncharacterized protein OS=Vitis vinifera GN=VIT_13s0019g02170 PE=3 SV=1 ---QDFFESNTPQTTRRAEGGL--IS---GGIPLPSCGFLHHRAGYLRGRWNDC--------------------------- ->tr|A0A212F231|A0A212F231_DANPL 3-dehydroecdysone 3alpha-reductase OS=Danaus plexippus plexippus GN=KGM_212779 PE=4 SV=1 -LDSDFIKNYKINTMGDRISSSEEVGHMILYLASDKAAGMTGMLTVI---------------------------------- ->tr|E7GJ29|E7GJ29_CLOSY Uncharacterized protein OS=[Clostridium] symbiosum WAL-14163 GN=HMPREF9474_00922 PE=3 SV=1 -------NISRKCGVLNRASLPEEIASLAAFLSTSTGKYVSGQTIIASACEEL---------------------------- ->tr|A5VEF2|A5VEF2_SPHWW Short-chain dehydrogenase/reductase SDR OS=Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) GN=Swit_4328 PE=3 SV=1 ---------ISAKRSHEWLKAPEDVVPLALFMACQPDVGPTAQSFSLMRrl-------------------------------- ->tr|A0A0H4KT16|A0A0H4KT16_9RHOB Dehydrogenase with variable specificity OS=Marinovum algicola DG 898 GN=MALG_00952 PE=3 SV=1 ---------PPGFPEWERLKHPDEVGELALYMATRPIGGPTGQSFSLARrpL------------------------------- ->tr|A0A0S4PIV3|A0A0S4PIV3_9BACT 3-oxoacyl-[acyl-carrier protein] reductase OS=Armatimonadetes bacterium GXS GN=GXSOP10_12229 PE=3 SV=1 ----------GYVPDRSKMIRPESVAQVVVNLLTlPPDAH-VDELILLPQE------------------------------- ->tr|A0A1F9AH68|A0A1F9AH68_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_61_14 GN=A2V67_10075 PE=3 SV=1 ----------RGWAEQSW-QPLELAGPLVTFLASgKADVLtgrwvgPKDDLPELIRriD------------------------------- ->tr|A0A178M5T7|A0A178M5T7_9CHLR Short-chain dehydrogenase OS=Chloroflexus islandicus GN=A6A03_02995 PE=3 SV=1 -------------VLNIFGTTAEETAELALRIVR---EGKNGQIFEVMPrhraI------------------------------- ->tr|A0A1V4MM28|A0A1V4MM28_9DELT Uncharacterized protein OS=delta proteobacterium ML8_D GN=AVO38_10710 PE=3 SV=1 ----------VEYNKKGYLKDPREVASLAVFLASsESDHLngyngTLGDYADLGWkr-------------------------------- ->tr|T1NTQ1|T1NTQ1_TRIUA Uncharacterized protein OS=Triticum urartu PE=4 SV=1 -SEFALREGELSRESFMLVADDDDAHGRRyVFEdVVMALLFVFGFWlktsvyCRLDNDNA----------------------------- ->tr|F8I372|F8I372_SULAT Short-chain dehydrogenase/reductase SDR OS=Sulfobacillus acidophilus (strain TPY) GN=TPY_1286 PE=4 SV=1 -LPLPQASRIQAQTRAGVWQSPEEVAEVIWRLLELPGDLMTGQVFYVNRGDVM---------------------------- ->tr|A0A1R0IR31|A0A1R0IR31_SULTH Uncharacterized protein OS=Sulfobacillus thermosulfidooxidans GN=BFX06_03180 PE=4 SV=1 -LTEEQKSRLIQQSASKKWIDPQDVAETLWDMIHNPPPS--GTVMMVN--------------------------------- ->tr|A0A1H8QTP7|A0A1H8QTP7_9ACTN Short-chain dehydrogenase OS=Streptomyces rubidus GN=SAMN05216267_103152 PE=4 SV=1 ---DARRRQLRETLPIRRVVGPEDVAAMGVHLML--NTALTGATYDVDGGQQF---------------------------- ->tr|A0A1F3T4F9|A0A1F3T4F9_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium GWB1_55_8 GN=A2X94_07910 PE=4 SV=1 ---KKARNEPggispdalakqihrrFRSRPNGQLYTPISVHAIYLLHAL--SATFTSRLLELLVARK----------------------------- ->tr|A0A154LBP0|A0A154LBP0_9PROT Uncharacterized protein OS=Thalassospira sp. MCCC 1A01148 GN=AUQ43_16105 PE=4 SV=1 -FAEGEIEKHVQQTPVGKLIALEDLVKICFDISQPHWASLNGQVIDINGGRYV---------------------------- ->tr|A0A0G2K6H4|A0A0G2K6H4_RAT Peroxisomal trans-2-enoyl-CoA reductase OS=Rattus norvegicus GN=Pecr PE=1 SV=1 -LGQTMFEMAFENIPAKRVGLPEETLPfgVLPTVPRSTPSLPGQVHINVRRQARLCT-------------------------- ->tr|D9XT94|D9XT94_9ACTN Short-chain dehydrogenase/reductase family oxidoreductase (Fragment) OS=Streptomyces griseoflavus Tu4000 GN=SSRG_05097 PE=4 SV= --GPRAGGPSSGPHPPRQVRRGRRDRRRR-RLPGQ-RRLLLR--------------------------------------- ->tr|B9T9R1|B9T9R1_RICCO Uncharacterized protein OS=Ricinus communis GN=RCOM_0057120 PE=4 SV=1 ----DIERLHISRTPLGRFADPDEMASAAIYFASDDASFITGQTLYVDGGRTVLAFVMPDKGKETSADP------------ ->tr|A0A212F231|A0A212F231_DANPL 3-dehydroecdysone 3alpha-reductase OS=Danaus plexippus plexippus GN=KGM_212779 PE=4 SV=1 ---MEELKDAKMSTISDRSSTSEEIGNLILYLASDKAVGMTGSNYVIDNGLLVLN-------------------------- ->tr|A0A1S4CVL5|A0A1S4CVL5_TOBAC tropinone reductase-like 3 isoform X2 OS=Nicotiana tabacum GN=LOC107823087 PE=4 SV=1 --------LVFRGENLRlrhySIGSEQHKT-WPRLLPIWHQ-------------------------------------------- ->tr|R2SV00|R2SV00_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_03196 PE=4 SV=1 -VNQEELNALAAGIPLGKIGDVSDISGCMEYIIN--APYVTGQTISPNGGFVM---------------------------- ->tr|A0A0L1HXQ9|A0A0L1HXQ9_9PLEO L-xylulose reductase OS=Stemphylium lycopersici GN=TW65_01850 PE=4 SV=1 ---PQVINEGLRMIPLGRQGNVKEIKGLFLQYGSTIPSLVLKLPAELRSIIYH---------------------------- ->tr|A0A0E1X5U5|A0A0E1X5U5_9RHIZ 7-alpha-hydroxysteroid dehydrogenase OS=Brucella pinnipedialis M292/94/1 GN=BALG_01829 PE=3 SV=1 -LTPEIERAMLKHTPLGRLGERRISPMRrcssvrppqhgsaVRFSRFPAAACRNSTDISLLrkqpiPT------------------------------- ->tr|W1Q812|W1Q812_OGAPD Putative oxidoreductase OS=Ogataea parapolymorpha (strain ATCC 26012 / BCRC 20466 / JCM 22074 / NRRL Y-7560 / DL-1) GN=HPODL_03 --TKERVEFFKTQSAYGRLTEISDIVPIITFLAKD-GHWITGQNLFANNGFTAPF-------------------------- ->tr|R0A7V2|R0A7V2_9FIRM Uncharacterized protein OS=[Clostridium] bolteae 90A9 GN=HMPREF1085_03792 PE=4 SV=1 --ETNRAEFNQRVERVplKRVGEPWEIGTMVAFLASDKCELAVGTCVDMTGGLLLGY-------------------------- ->tr|A0A0Q9RWC1|A0A0Q9RWC1_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil796 GN=ASH02_08400 PE=4 SV=1 -ADPvRaeTYERLRQRTPGKRLPEPAHIVAAAFALID--NPGINAANLVVDAGMHL---------------------------- ->tr|A0A161UKI5|A0A161UKI5_9MICO Putative oxidoreductase OS=Microbacterium sp. TNHR37B GN=fabG2 PE=4 SV=1 -KPEGVLSGYESRTPGGALATMLDVVDATKFLLF--NRGVSAHSLNVDRGWRI---------------------------- ->tr|A0A239ND76|A0A239ND76_9ACTN Short-chain dehydrogenase OS=Streptomyces glauciniger GN=SAMN05216252_13382 PE=4 SV=1 -NEQLqdGA---RKMTLTGRLATMADIVDGCLFLLE--NPMANGIDLTLNGGIA----------------------------- ->tr|A0A0B2WX97|A0A0B2WX97_9HYPO Oxidoreductase OS=Metarhizium album ARSEF 1941 GN=MAM_04510 PE=4 SV=1 -------IRDLYARQGLSMCGADEVARTIVWLLSQDSHPVYGANINVGAGV------------------------------ ->tr|G4MPN0|G4MPN0_MAGO7 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_02225 P -------EVAAQAQ-NAGCILPEEAAEAIVWLLSENCLQLNGIAVPIGEMD------------------------------ ->tr|R0IRG4|R0IRG4_SETT2 Uncharacterized protein OS=Setosphaeria turcica (strain 28A) GN=SETTUDRAFT_19988 PE=4 SV=1 --------QQKPGGLFANPIDSAHISKVMVWLLSDTASHVNGINMLVGATT------------------------------ ->tr|A0A0D2FQX8|A0A0D2FQX8_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.4, whole genome shotgun sequence OS=Rhinocladiella ma -------AVADMAKRGITLLEPEWVSDTIVWLLGEESAGISGVNIPIGASA------------------------------ ->tr|A0A094EMQ5|A0A094EMQ5_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. VKM F-103 GN=V499_02946 PE=4 SV=1 ----ELMAMELKKIPIGRLAESEEIAQAISYLASPMSSYMTGAGLVVDGGYTTPPRFP-FSRPYAAEPPA----------- ->tr|T1KZC5|T1KZC5_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1 --PDEIWDNFAKMMPLKRVAEPIEMAQLIALVASDVSKNMTGSIVASDSGYLLGDPYS-------SGRPLVKLLLSHHKP- ->tr|T0K262|T0K262_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_10902 PE=4 SV=1 ---EEAIAGFVQNQLVREVGTVQQTAEAYLFSMRC--SFATGQQFVIDGGYTY---------------------------- ->tr|A0A0L0NME7|A0A0L0NME7_9HYPO Glucose and ribitol dehydrogenase-like protein 1 OS=Tolypocladium ophioglossoides CBS 100239 GN=TOPH_00048 PE=4 SV=1 ---DSVTARLKGRMTTGAIGQVEDVAEAYLYLMKD--KNASGSVVETTGGTLL---------------------------- ->tr|A0A0F9X2L0|A0A0F9X2L0_TRIHA Short chain dehydrogenase OS=Trichoderma harzianum GN=THAR02_08975 PE=4 SV=1 ---EEIGKDIAKDTLTGIFAYAEDVAVRPQYILCK--RFQKEANSQRRKPTYT---------------------------- ->tr|A0A0B8MXZ2|A0A0B8MXZ2_9EURO Short-chain dehydrogenase OS=Talaromyces cellulolyticus GN=TCE0_011r00544 PE=4 SV=1 ---EDRIEAAARKALLGKLGTPEETAEAYIYLMRD--TTATGVFINNSGGELL---------------------------- ->tr|A0A0C3HAE5|A0A0C3HAE5_9PEZI Uncharacterized protein OS=Oidiodendron maius Zn GN=OIDMADRAFT_56479 PE=4 SV=1 ---SAQVAAISETLPQKKIGTVEEAAQSYIYLMKD--TNATGGVVNTKAKNY----------------------------- ->tr|Q9YC93|Q9YC93_AERPE Putative oxidoreductase OS=Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) GN=APE_1361.1 PE=4 S --LENVWRrEVEMLSPLARSGGLDEFEEVIRMLV-RSPDYMHGATVVFDGASG----------------------------- ->tr|Q9V1Q9|Q9V1Q9_PYRAB Glucose-1-dehydrogenase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=PAB0245 PE=4 SV=1 --MDEIWErEVIDRTPLKRTGRWSELGALIDFLLSENAEYMLGSTIVFDGAMT----------------------------- ->tr|A0A223SAM0|A0A223SAM0_9ACTN Uncharacterized protein OS=Nocardiopsis gilva YIM 90087 GN=CDO52_21935 PE=4 SV=1 ---EDFKKAAAEGIPVRRVGQPEDIANTVSFLTSEASGFVSGQVIYVAGGPSTDAPPAAPGRRPHGGPPAVPSPPGSPTP- ->tr|A0A1F7FGQ3|A0A1F7FGQ3_9BACT Uncharacterized protein OS=Candidatus Raymondbacteria bacterium RIFOXYD12_FULL_49_13 GN=A2519_03765 PE=4 SV=1 ---PG-Q----------TWGTIAGLLKAFRYLVE---SEATGQIMYCDQGLRLF--------------------------- ->tr|A0A0G4L408|A0A0G4L408_9PEZI Uncharacterized protein (Fragment) OS=Verticillium longisporum GN=BN1723_010999 PE=4 SV=1 ---RAKLeSIMNASTLTRSIGEPADVAEAYIYCMRD--NNVTGASIDSTSGHIL---------------------------- ->tr|A0A177C8R8|A0A177C8R8_9PLEO NAD(P)-binding protein OS=Paraphaeosphaeria sporulosa GN=CC84DRAFT_1151685 PE=4 SV=1 ---QAFFEGSKTSLFTGRVPTAEDVAESFIGIMKD--YNMDASMVRSDGGSLF---------------------------- ->tr|A0A0N0NR97|A0A0N0NR97_9EURO Glucose and ribitol dehydrogenase OS=Phialophora attae GN=AB675_8564 PE=4 SV=1 ---EQTRQYMAQHLLGKRVPKPEDAAEQYLASMRD--ANSTGTLYGTNGGELI---------------------------- ->tr|A2R8G7|A2R8G7_ASPNC Aspergillus niger contig An16c0230, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An16g07090 PE=4 SV= ---DMYMEMFRKGTVLGRVGAPEDVAEAYLWWGVR--ERGRELVVGDGGMGMR---------------------------- ->tr|A0A166VIT4|A0A166VIT4_9PEZI Short chain dehydrogenase/reductase family OS=Colletotrichum tofieldiae GN=CT0861_02648 PE=4 SV=1 ---EVMRTFLSNKSLLCRIGDAEDLAEAYLSIMKN--YFVTGTIMHVNGGLML---------------------------- ->tr|A0A078AFE5|A0A078AFE5_STYLE Dehydrogenase reductase sdr family member 4 OS=Stylonychia lemnae GN=Contig6085.g6510 PE=3 SV=1 ------QKSRKQELNPKIYGQPSQIASIVATmCSED--GS------FVNGETYF---------------------------- ->tr|W9VKY4|W9VKY4_9EURO Uncharacterized protein OS=Cladophialophora yegresii CBS 114405 GN=A1O7_09104 PE=4 SV=1 -----------EKALLRSMEGMRSVANATAWLSSPGSGWLTGLVVPVDKGRNLNCVW------------------------ ->tr|A0A101QHA0|A0A101QHA0_STRAT Uncharacterized protein OS=Streptomyces antibioticus GN=AQJ23_03780 PE=3 SV=1 -VDPERRSYM-ANRALMGLGDGQQVADTIAFLAGPAADYINATTVHADGGVRY---------------------------- ->tr|A0A024G777|A0A024G777_9STRA Uncharacterized protein OS=Albugo candida GN=BN9_031580 PE=4 SV=1 -----------------FIKYGEDATNMVLHFVSDQIRCMKGVSVVLHENA------------------------------ ->tr|A0A0F3GNH9|A0A0F3GNH9_9BACT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Candidatus Magnetobacterium bavaricum GN=MBAV_004278 PE=3 SV=1 ----------EKTNFRKKALDASEIADVIVYLLSKRSAVINGQIIVSDAGTMLNP-------------------------- ->tr|A0A1F6DUC8|A0A1F6DUC8_9BACT Uncharacterized protein OS=Candidatus Kaiserbacteria bacterium RIFCSPHIGHO2_02_FULL_55_17 GN=A3C94_01690 PE=4 SV=1 --NAKdpaalegILAAIKKRMPAHELIPSEAVAEYIVHLAAGGARWVTGQVTDFDAGYTRNI-------------------------- ->tr|A0A1J5CU48|A0A1J5CU48_9BACT Uncharacterized protein OS=bacterium CG2_30_33_46 GN=AUJ93_02465 PE=4 SV=1 ----NMLKAYKLATPF--VVDQQEVGRVCVALASGYLKSLTGSVLHADGGFHV---------------------------- ->tr|A0A1J1EJB8|A0A1J1EJB8_THETH Enoyl-ACP reductase OS=Thermus thermophilus GN=fabL PE=4 SV=1 ---TKMYDRVAQTAPSGGTSPRRRWATSASSSSPPWRAASPGRWStwtraTTSWGWSWKGSPP----------------------- ->tr|A0A1L8S1W4|A0A1L8S1W4_9ENTE Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Enterococcus caccae GN=RU98_GL000802 PE=3 SV=1 ---DQLIKISEGRTPDKAGVTIEEVGNTCAFLVSELAAGIVGDIIYVDKGVHLT--------------------------- ->tr|W2S0I5|W2S0I5_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_04044 PE=3 SV=1 -----VEGNDAEVHLSNRAGMPEDISEAVEYLLG--AGFGEFsflQSIVLRGSVP----------------------------- ->tr|A0A0P0YG49|A0A0P0YG49_9PROT Short-chain dehydrogenase/reductase SDR OS=Asaia bogorensis NBRC 16594 GN=Asbog_01041 PE=3 SV=1 --PAQAWKDRARTEVQPvGWLQPEDISPVAVFLASDASALTTGAEFEVNGGDSALM-------------------------- ->tr|A0A078ASB0|A0A078ASB0_STYLE Dehydrogenase reductase sdr family member 4 OS=Stylonychia lemnae GN=Contig14931.g15915 PE=4 SV=1 -----------TQKIPRIISEPHNVASIAAMITSDDGSFINGESHVIESKVL----------------------------- ->tr|H0E2V1|H0E2V1_9ACTN Putative rhamnulose-1-phosphate aldolase OS=Patulibacter medicamentivorans GN=PAI11_11160 PE=4 SV=1 --PDQLEEHYRQRNTLKVLILPEDIAAATLHFASPaRSGKSTGNVLNVDGGVPAAYPR------------------------ ->tr|A0A0J9EAA4|A0A0J9EAA4_9RHOB Putative oxidoreductase OS=Candidatus Rhodobacter lobularis GN=AIOL_004543 PE=4 SV=1 --EET----YMGGNLLGREVEARHVADGFVNLAL--MERTTGHVVTVDGGNTEAELR------------------------ ->tr|L8M1W1|L8M1W1_9CYAN Uncharacterized protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00010380 PE=4 SV=1 --VEE----YKTNNVLKVEVTSESVGELAVELCT-pLFANTTAAQIPIDGGNERVI-------------------------- ->tr|A0A1B5ZTD3|A0A1B5ZTD3_9FLAO Diacetyl reductase OS=Arenibacter sp. C-21 GN=budC PE=4 SV=1 --VDELPAHYAKRNLLNEIIYPEDIANGVFACVA-ILDKTTGNIINVDGGMANAFVR------------------------ ->tr|A0A1G2Y8P8|A0A1G2Y8P8_9BACT Uncharacterized protein OS=Planctomycetes bacterium GWF2_50_10 GN=A2Y07_06015 PE=4 SV=1 --PQEVIPYYVNKTHLKREIKGQDIADSVVFLCS-dKARVITGQVIVADSGQVMVR-------------------------- ->tr|A0A1M5KW73|A0A1M5KW73_9BACT Rhamnulose-1-phosphate aldolase/alcohol dehydrogenase OS=Aliifodinibius roseus GN=SAMN05443144_1358 PE=4 SV=1 --FDeeestetlreTLADFYASRTLTRQPITLDQQTEAIYSLIS-sRYENTTGHIIPVDGGLKEAFLR------------------------ ->tr|A0A227SLY5|A0A227SLY5_CRYNV Cytoplasmic protein OS=Cryptococcus neoformans var. grubii Th84 GN=C355_04872 PE=4 SV=1 -----WVKEWEKRSPVSQFVTTYEIGRFVATPLSdkiGRMGFMAGSEIAIGGAS------------------------------ ->tr|A0A0U0W5X6|A0A0U0W5X6_9MYCO Short chain dehydrogenase OS=Mycobacterium bohemicum DSM 44277 GN=BN971_00980 PE=4 SV=1 -------GALAQLGALKRFGRPSEIAELLAFCASDKPGYLTGTDIICDGGVMAAMRPKDMLKLARSQ-------------- ->tr|C1AR26|C1AR26_RHOOB Uncharacterized protein OS=Rhodococcus opacus (strain B4) GN=ROP_02560 PE=4 SV=1 -------------FAAPG-PGDREVAAVASYLCAPAGMFVTGAAYVVDGARIAMIPHSL---------------------- ->tr|I0BSM8|I0BSM8_9BACL Short-chain dehydrogenase OS=Paenibacillus mucilaginosus K02 GN=B2K_32500 PE=3 SV=1 -------------------RDPFLVAPEIVALAAPDGSRFSSRLVLAGGSHGERT-TR-YRIER----------------- ->tr|N0B188|N0B188_9BACI Short-chain dehydrogenase/reductase SDR OS=Bacillus sp. 1NLA3E GN=B1NLA3E_11190 PE=3 SV=1 -------------------DDPANVAPYILELAKRKST-HEKKVIQLEDLSHSVK-AR-K--------------------- ->tr|A0A1E5LK25|A0A1E5LK25_9BACI Short-chain dehydrogenase OS=Bacillus solimangrovi GN=BFG57_07935 PE=3 SV=1 -------------------DDPANIAPYLVELATGDYE-VQKYVFDTSSISLEKT-YH-QS-------------------- ->tr|A0A1F3ZKN9|A0A1F3ZKN9_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_62_17 GN=A3H35_08350 PE=3 SV=1 -------------------MFPHDIGRLATLMCSLPEEVNLFS---aiilpnhmpsfIGRG------------------------------- ->tr|A0A1H8PYU6|A0A1H8PYU6_9ACTN Short-chain dehydrogenase OS=Streptomyces rubidus GN=SAMN05216267_102776 PE=4 SV=1 -------------------QDPRQIGDELHRQF--VTSYEQGRLITAERSAASLL-GH-LGTED----------------- ->tr|A0A1Q8UXJ0|A0A1Q8UXJ0_BACPF Short-chain dehydrogenase OS=Bacillus pseudofirmus GN=BTR23_06150 PE=3 SV=1 -------------------EDPKDIAPILLDIASQVEL-GHGKIITADEWKLKLE-KN-LSTN------------------ ->tr|A0A178C0B4|A0A178C0B4_9EURO Uncharacterized protein OS=Fonsecaea multimorphosa GN=AYO22_06390 PE=3 SV=1 ---EP---MLAMTPAASRLGETEEMAYAAAFFCEERGRWMTGVCLAVNGGTLM---------------------------- ->tr|B5GK28|B5GK28_STRSH 3-alpha-(Or 20-beta)-hydroxysteroid dehydrogenase (Fragment) OS=Streptomyces sp. (strain SPB074) GN=SSBG_04637 PE=3 SV=2 --PPSRRASRWAGSPSRRR-SPASCSSSppTKPLTSPAPPTSRTAECSPA--------------------------------- ->tr|B2J677|B2J677_NOSP7 Short-chain dehydrogenase/reductase SDR OS=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) GN=Npun_R2173 PE=4 SV=1 ---EKLIPYWESISLGNKLCMPEDVADMVSYLLREEVKRINGSILLIDAGQSIH--------------------------- ->tr|A0A0K9N7K2|A0A0K9N7K2_9FIRM Alcohol dehydrogenase OS=Dorea sp. D27 GN=HMPREF0980_03184 PE=4 SV=1 -MTPEERAAFDAAQAKKRLIQPSEIAFWLGELLRDESTLMHGANIDATMGL------------------------------ ->tr|A0A0G4J4J7|A0A0G4J4J7_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_002436 PE=4 SV=1 -ELA--MPMTRGMLAKGRLIDPREIADVIYWICTQaQARVFHGAVLDASMGL------------------------------ ->tr|T0RYZ8|T0RYZ8_9DELT Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Bacteriovorax sp. DB6_IX GN=M901_1207 PE=3 SV=1 -LDQEQRDELISSLAKKRLIDPKEIANLCSFLISEQSQILHGAILDSSLGL------------------------------ ->tr|A0A0L9TVV8|A0A0L9TVV8_PHAAN Uncharacterized protein OS=Phaseolus angularis GN=LR48_Vigan02g046900 PE=3 SV=1 -----LKTVAMKTVPLRSYGTSDpALTSLARYLIHDSSEYVSGNNFIVDAGATI---------------------------- ->tr|A0A096RVL4|A0A096RVL4_MAIZE Uncharacterized protein OS=Zea mays GN=si606063d04 PE=3 SV=1 -----LSTVASKIVPLKEHGATDpALTSLVRFLIHEASSYVTGNIFIVDSDLLR---------------------------- ->tr|A0A0Q3FI94|A0A0Q3FI94_BRADI Uncharacterized protein OS=Brachypodium distachyon GN=BRADI_3g40050 PE=3 SV=1 -----LKTVVSKIVPLKTHGTTDpALTSLEPVKFIDNEALEA-----IMLGAHL---------------------------- ->tr|A0A1S3C2F6|A0A1S3C2F6_CUCME 3-oxoacyl-[acyl-carrier-protein] reductase FabG-like isoform X1 OS=Cucumis melo GN=LOC103495898 PE=4 SV=1 -----IKNVARRMNPLGTFGTSNpALTTTIRYLVHDSSKYVSEQERNRKkKKKSM---------------------------- ->tr|A0A094QCX0|A0A094QCX0_9ZZZZ Uncharacterized protein OS=freshwater metagenome GN=GM51_5865 PE=4 SV=1 --DPEVRAKIESQVPMRRLGTMTEFAAFCMAFLDGSSRFTTGQFVAYAGGWA----------------------------- ->tr|A0A1D8AEI2|A0A1D8AEI2_9SPHN Uncharacterized protein OS=Novosphingobium resinovorum GN=BES08_27120 PE=4 SV=1 --RhvpsGPWSRQLESESPAGRMGTMAELAAFCMPLLDGSSRYQTAQYFSFSGGWN----------------------------- ->tr|A0A1L8PH79|A0A1L8PH79_9LACT Uncharacterized protein OS=Alkalibacterium sp. 20 GN=AX762_01500 PE=4 SV=1 ----DLVKEMEKDIPMKHIAEPKEISNLLLYLSSDESIYSTGIEFVVDGGLIQVMYKAGEK-------------------- ->tr|Q8YQL6|Q8YQL6_NOSS1 All3805 protein OS=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) GN=all3805 PE=3 SV=1 -IDTPANRQAMGTENADKWVKPESIGELICFLASEKAKDIRGAAIPIYG-------------------------------- ->tr|A0A1C1CV69|A0A1C1CV69_9EURO Uncharacterized protein OS=Cladophialophora carrionii GN=CLCR_10276 PE=4 SV=1 --------ELFKAMPAARIGRAEDIVGAVLYLSSQAGGWAKTRRRLMSMEDAFAWMVA----------------------- ->tr|R7ZP94|R7ZP94_9BACT Short-chain dehydrogenase/reductase SDR OS=Lunatimonas lonarensis GN=ADIS_3602 PE=4 SV=1 ---------------FTKWVSPAEIAEAMHYAANSEA--LRNMTFKLYGG------------------------------- ->tr|A0A1Q3TBN3|A0A1Q3TBN3_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 44-61 GN=BGO52_13740 PE=4 SV=1 ---------------FSKWVTPESIADIVYAHCDPSFDALREPLIKIYNK------------------------------- ->tr|A0A0G4L4J6|A0A0G4L4J6_9PEZI Uncharacterized protein (Fragment) OS=Verticillium longisporum GN=BN1708_017529 PE=4 SV=1 --DQAKRQRREIHFPTGRFGEAVEQAQAVLFLASDEASFVNGHDMVVDGGMTKAYVTP---EGPASAAPMKENIPSS---- ->tr|A0A1X2LC17|A0A1X2LC17_9MYCO Uncharacterized protein OS=Mycobacterium vulneris GN=B8W69_03540 PE=4 SV=1 ---------WMTSQSGGRKAAPGEVADALAFLGSDAASYINGTNLLIDNGFSAAITTN---QIDYSSMPAVDALTNS---- ->tr|U1HPM8|U1HPM8_ENDPU Uncharacterized protein OS=Endocarpon pusillum (strain Z07020 / HMAS-L-300199) GN=EPUS_03294 PE=4 SV=1 -------DVQKANIGLERAGHPAEVAKVAGFLAPAASAATSPART-----SWSMV-------------------------- ->tr|H9UMQ3|H9UMQ3_SPIAZ Uncharacterized protein OS=Spirochaeta africana (strain ATCC 700263 / DSM 8902 / Z-7692) GN=Spiaf_2772 PE=4 SV=1 -LNSEQRARYSRLAGTRGLSNPDICAQLVWRIAEREEIFQNGAIINMQTYRK----------------------------- ->tr|F8EYG9|F8EYG9_TRECH Short-chain dehydrogenase/reductase SDR OS=Treponema caldarium (strain ATCC 51460 / DSM 7334 / H1) GN=Spica_0233 PE=4 SV=1 -LDEQARRYALGKAPGGILLQCEDIAETA--LAILHNPHQNGTIIALDKGLV----------------------------- ->tr|F4LL84|F4LL84_TREBD Short-chain dehydrogenase/reductase SDR OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=Trebr_2249 PE=4 S -QPDSLKAVLARKMPTGAMIAPEAIAEAVLF--LLKTPEINGALLNVDAGWV----------------------------- ->tr|A0A1G3RJ60|A0A1G3RJ60_9SPIR Uncharacterized protein (Fragment) OS=Spirochaetes bacterium RIFOXYC1_FULL_54_7 GN=A3J97_03890 PE=4 SV=1 -LDPGKRDNFAKLAPGGRLTKPDRIAAFVVNLLLGDMALVSGSVINTDDGLY----------------------------- ->tr|A0A1G3LTV5|A0A1G3LTV5_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_59_5 GN=A2Y38_19735 PE=4 SV=1 -LDDQTKIRLSAASPRGGLIPESEIAALVRYMVSGGMDLANGSIIVADRGLY----------------------------- ->tr|A0A1V6E2W9|A0A1V6E2W9_9SPIR 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Spirochaetes bacterium ADurb.Bin110 GN=fabG_6 PE=4 SV=1 -LDRETIIRHASLTATGSLSKADIIASIALNLIDAEPCIASGAVVNLDGGFA----------------------------- ->tr|B7FS72|B7FS72_PHATC Enoyl-acp reductase OS=Phaeodactylum tricornutum (strain CCAP 1055/1) GN=FABI PE=4 SV=1 ---EYAIDYSKANAPLEQDLYSDDVGNASLFLTSPMARTVTGVTLYVDNGLHS---------------------------- ->tr|Q0UVU3|Q0UVU3_PHANO Uncharacterized protein OS=Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) GN=SNOG_04121 PE=4 SV=2 --NPEAVEKNLQFPVMKRRAEAEEVAHVIAFLLSEKASFVTGAVWNIDGGWPSAPQTH--------YSFFPKALPNGPPP- ->tr|W4VHV7|W4VHV7_9BACI 3-oxoacyl-[acyl-carrier protein] reductase OS=Gracilibacillus boraciitolerans JCM 21714 GN=JCM21714_1994 PE=4 SV=1 ----ESRKKHDPYTPIGRSGTGEDIARMVLFFCENKSDMITGTVVDVNGGLDVIHQQR-K--------------------- ->tr|A0A1S9R8W1|A0A1S9R8W1_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PEBR_41300 PE=4 SV=1 ----DTIQKIASHNPFKRIADPDEIAGAVSLLWKDESRWITGQVVKVNGGIGHTLAER----------------------- ->tr|A0A0P1B2Z3|A0A0P1B2Z3_9STRA Peroxisomal trans-2-enoyl-reductase OS=Plasmopara halstedii PE=4 SV=1 ---EMFVYAAEKITAAKRMGSVEEVSASVLYYLSPAGAYITgdtmhvdggwhllGPLIDVPEH------------------------------- ->tr|A0A0S8ESH9|A0A0S8ESH9_9DELT Uncharacterized protein OS=Myxococcales bacterium SG8_38_1 GN=AMJ63_12220 PE=4 SV=1 ---PELLANAEKSNPLKRLGTAEEVSHLITYLASRYADFIAgqtfyidggasiwGEQWFLPED------------------------------- ->tr|E4X740|E4X740_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00003201001 PE=4 SV=1 ---KEIFDKSAANVPKKRLGELYEGAnlsegtlsldliPQILFNLTDAVQYTTgwketldsrtklvL--------------------------------------- ->tr|B6QAJ7|B6QAJ7_TALMQ Polysaccharide deacetylase family protein OS=Talaromyces marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333) GN=PMAA_073690 PE --ILPMYVS-TSNLRYRKhpkpsqdtSLQLKALVRATTFLASHsEAGHLSGECLGVDNVN------------------------------ ->tr|A2QAZ6|A2QAZ6_ASPNC Aspergillus niger contig An01c0400, genomic contig OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=An01g13340 PE=4 SV= ------FLI---IPEIHPltsssishSTTTDSISRTIAFLASHrAAGHLTGQCLNQNNNT------------------------------ ->tr|W7EDS8|W7EDS8_COCVI Uncharacterized protein OS=Bipolaris victoriae FI3 GN=COCVIDRAFT_18586 PE=4 SV=1 ------------------lggDATDLSIISAMNILATSsSRGSVISL-------------------------------------- ->tr|A0A0G4PIA7|A0A0G4PIA7_PENCA Glycoside hydrolase/deacetylase, beta/alpha-barrel OS=Penicillium camemberti FM 013 GN=PCAMFM013_S016g000207 PE=4 SV=1 ------------------srEASTQSIVAATAILGSAkPVRGIISL-------------------------------------- ->tr|W4JYI4|W4JYI4_9HOMO Uncharacterized protein OS=Heterobasidion irregulare TC 32-1 GN=HETIRDRAFT_435860 PE=4 SV=1 ------------ETPTLPNGTRRDMGSLALMLIA--NWFINGETVLIDGGTLLKHPS------------------------ ->tr|A0A174SJN8|A0A174SJN8_9FIRM Sorbitol-6-phosphate 2-dehydrogenase OS=Faecalibacterium prausnitzii GN=srlD PE=4 SV=1 ---EDVRKFYMDQVPMRKGTGPEDVTKAVLYLIEQ--TCETGQAVPVTGGQVMLS-------------------------- ->tr|A0A0S8HHP2|A0A0S8HHP2_9BACE Uncharacterized protein OS=Bacteroides sp. SM23_62_1 GN=AMS27_09035 PE=4 SV=1 ---EDVRNYYEQLVPMKRGCTVADIMKTIYYLIDQ--QYETGQALPVTGGQIMLN-------------------------- ->tr|X7ZXS0|X7ZXS0_MYCXE Enoyl-(Acyl carrier ) reductase family protein OS=Mycobacterium xenopi 4042 GN=I553_5517 PE=4 SV=1 ------IARVAATVPLGRLAKPADIGWAAAFLASDLASYISGATLAVHGGGEPRRIWP-RRAPTSKGATGMGLV------- ->tr|A0A0D2XP69|A0A0D2XP69_FUSO4 Uncharacterized protein OS=Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) GN=FOXG_05 --------AIAASVPVRRLGHPQEVANIAVMLDG--KNWISHRARYHLVWW------------------------------ ->tr|W1MG22|W1MG22_PSEAI Uncharacterized protein OS=Pseudomonas aeruginosa VRFPA03 GN=M770_25245 PE=3 SV=1 ---RWTSPTPCSSSPPTRRATSPGRPW--LWMAArccrRTAGWPEAA----GVR------------------------------- ->tr|A0A094DJ73|A0A094DJ73_9PEZI Uncharacterized protein (Fragment) OS=Pseudogymnoascus sp. VKM F-4515 (FW-2607) GN=V496_03342 PE=4 SV=1 -IPKETVEMQKASTPVQnRIGTVDDIAQIVLWMASEGSRWVTGQVVSASGGWAMY--------------------------- ->tr|A0A160VHR0|A0A160VHR0_9ZZZZ Oxidoreductase, short chain dehydrogenase/reductase family OS=hydrothermal vent metagenome GN=MGWOODY_Mmi1082 PE=4 SV=1 ---EAWVENTKKRNPMRRTTTPEDVAGTISMLLKPEADFINCSIIYCDGGESRSGTF------------------------ ->tr|D8SBE7|D8SBE7_SELML Putative uncharacterized protein OS=Selaginella moellendorffii GN=SELMODRAFT_444601 PE=4 SV=1 -----YEAAVLDRTPARRVGEPREVAAVAAFLALPASSYVTGQERHLLMVswcsdtLKvSGEVGHHDTLKRWS--------------- ->tr|T1GZE3|T1GZE3_MEGSC Uncharacterized protein OS=Megaselia scalaris PE=4 SV=1 --SESANEAALSKIPMQRLGTK--MVGVYSFLVFKDAAYTTGRKSSCSYYFHRRY-------------------------- ->tr|A0A0F0KLS6|A0A0F0KLS6_9MICO Putative ketoacyl reductase OS=Microbacterium foliorum GN=actIII_1 PE=4 SV=1 -------RAMGAATPVGRSGTADEVASVIGFLADEAASYITGQLITVDGGQLHHRRTR-ALRPVTKERRELTMNENT---- ->tr|K1LD52|K1LD52_9BACT Cyclopentanol dehydrogenase OS=Cecembia lonarensis LW9 GN=cpnA_3 PE=4 SV=1 -LSENWYEEIpAMYAPSGRILWPSEIAAAAVYWLADESGPISGQVVDLEQHPLMGRN------------------------- ->tr|A0A143PNZ1|A0A143PNZ1_9BACT 4-formylbenzenesulfonate dehydrogenase TsaC1/TsaC2 OS=Acidobacteria bacterium DSM 100886 GN=tsaC1_2 PE=4 SV=1 -KGDEWVAEAVKTRPFGRLLEPADTAYAVAYYVSDAGACVTGSVMDLEQYPVGAPP------------------------- ->tr|A9KFX8|A9KFX8_COXBN Short chain dehydrogenase OS=Coxiella burnetii (strain Dugway 5J108-111) GN=CBUD_1365 PE=4 SV=1 -FPENWESKIpPTYAPSGRLIHPEDVARHAVFWASDVSAPANAVVYELEQYPVIGRN------------------------- ->tr|A0A059FU65|A0A059FU65_9RHOB Short-chain dehydrogenase OS=Hyphomonas johnsonii MHS-2 GN=HJO_02710 PE=3 SV=1 ------------------QFHIDRVAPTLLYMVSDLSGDQTGKTLLAGGGWIGEVRF------------------------ ->tr|A0A1H0A4W0|A0A1H0A4W0_9PSEU NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Allokutzneria albata GN=SAMN04489726_5886 PE=4 SV=1 ------------------LFTLDNCAALVAFLVSEASAYISGKVFGVQESNVEIYQS------------------------ ->tr|A0A1Q5GPW0|A0A1Q5GPW0_9ACTN Uncharacterized protein OS=Micromonospora sp. TSRI0369 GN=AMK25_28930 PE=3 SV=1 ------------------GIAPEANVPLLLYLLSDLSVGLTGQVLRSYGSELMLTTH------------------------ ->tr|A0A074YAP8|A0A074YAP8_AURPU NAD(P)-binding protein OS=Aureobasidium pullulans EXF-150 GN=M438DRAFT_335658 PE=3 SV=1 -------EDFEGKVFAQRPGNDRDMGNAMLFVAS--NQYLSKASIRTWGSRARIADH------------------------ ->tr|A0A0E4CSX2|A0A0E4CSX2_9STRE Short chain dehydrogenase OS=Streptococcus varani GN=BN1356_01390 PE=4 SV=1 --DPVVEEGRKALTANKRIGNTMDIANAVMYLASDRSDYTNGHELRVEGGFGIMMGDQ-TPKPGGRREFAVK--------- ->tr|G8YMK6|G8YMK6_PICSO Piso0_001215 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0 ----------------RVPVPASEIFRTVKFLIE--SKWINGEDIRVDGGWRLVVNRPKGETDARSLAPGLE--------- ->tr|A0A0D0TH64|A0A0D0TH64_CRYGA Unplaced genomic scaffold supercont1.15, whole genome shotgun sequence OS=Cryptococcus bacillisporus CA1280 GN=I312_05139 PE=4 ----------------HRVSEPTEVSAAVSFILE--NPMLNDMDLRVDGGWRNSSNWg-GE-KDRESLVHMFG--------- ->tr|A0A1Y2B7F5|A0A1Y2B7F5_9TREE Uncharacterized protein OS=Naematelia encephala GN=BCR39DRAFT_528245 PE=4 SV=1 ----------------RVPLTADQITPTIHYIIE--NVGVNGIDIPVDGGWRLVSSKagLAGGEDPRSLAPGLE--------- ->tr|A0A0N1P2E6|A0A0N1P2E6_9EURO Putative NADP-dependent mannitol dehydrogenase OS=Phialophora attae GN=AB675_6410 PE=4 SV=1 -PVSDAKDQWLKQIPMGWLYSQILPRVQAL--T-DQPQVVLRVPMSLAPLW------------------------------ ->tr|A0A0F7TXT5|A0A0F7TXT5_9EURO Uncharacterized protein OS=Penicillium brasilianum GN=PMG11_10002 PE=4 SV=1 --SPEDSAIMDIAPPLGRIGNFNDLTGAVIYLLSDASAYTTGADIPITGGLHIGR-------------------------- ->tr|A0A1V1TRU0|A0A1V1TRU0_9FUNG Uncharacterized protein OS=fungal sp. No.14919 GN=ANO14919_131970 PE=4 SV=1 -MTDEMRQARINQNLMKKEGTGWDVGYGRQSYYEAIKDI------------------------------------------ ->tr|A0A0P4R5L9|A0A0P4R5L9_9ACTN Oxidoreductase OS=Streptomyces sp. NBRC 110027 GN=TPA0598_03_08090 PE=4 SV=1 -------EMYYRELPWGRPLRLDEVAAACIELATaPQWAYATGQTYPLGAA------------------------------- ->tr|A0A0H5PAZ0|A0A0H5PAZ0_NOCFR 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Nocardia farcinica GN=fabG_28 PE=4 SV=1 -------ADYYARLPWGRALSIDEVAQTTVAVVCdPSWQYVSGQIIRLDAD------------------------------- ->tr|A0A0W1A9S8|A0A0W1A9S8_9GAMM 3-oxoacyl-ACP reductase OS=Legionella steigerwaltii GN=fabG_3 PE=4 SV=1 ---PAYQEKMAQIIPQGMMGETAQVAEAMDPLLSR-TSFMTGSVITVSGGLPLMRS------------------------- ->tr|G8T8K3|G8T8K3_NIAKG Enoyl-(Acyl-carrier-protein) reductase (NADH) OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_3889 PE -----LIAQYKAFDILKMSPTLKQLGDTAAFLASDTGVAFNSHVVDVDCGKLN---------------------------- ->tr|A0A1A3EWL1|A0A1A3EWL1_9MYCO Short-chain dehydrogenase OS=Mycobacterium colombiense GN=A5623_20250 PE=4 SV=1 -----FAAKMAANSHRNRATTLVELAQAAVLVASDRASAMTGTVANLTGGIIV---------------------------- ->tr|A0A1H1TBZ0|A0A1H1TBZ0_9MICO NADP-dependent 3-hydroxy acid dehydrogenase YdfG OS=Microterricola viridarii GN=SAMN04489834_1737 PE=4 SV=1 -----FAGFLESLTTSRSLPSLDEVAEMAVFLAEGGARSMNGAVLNLTCGMSP---------------------------- ->tr|A0A1M7JTF0|A0A1M7JTF0_9BACT NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Chitinophaga jiangningensis GN=SAMN05444266_10912 P -----VAANYTRFDILKTVPTLKQLGETAAFLVSDNGMVFNSHIVDFDCGKLN---------------------------- ->tr|A0A0Q1DJ48|A0A0Q1DJ48_9FLAO Uncharacterized protein OS=Flagellimonas eckloniae GN=AAY42_01830 PE=4 SV=1 -----MQQFIVENkTAMKKLPSTENTANVVVLAASELASYMTGTVINQSVGHIL---------------------------- ->tr|A0A1V5F7G8|A0A1V5F7G8_9BACT 3-oxoacyl-(Acyl-carrier-protein) reductase FabG OS=Bacteroidetes bacterium ADurb.BinA395 GN=fabG_1 PE=4 SV=1 -VPETYQDSIKSQIPTQRFCEPEDILKTVEYIR--NTPYLNGSSIDLNGAL------------------------------ ->tr|E4ZNP1|E4ZNP1_LEPMJ Putative uncharacterized protein OS=Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) GN=LEMA_P041610. ----EMAKEHKEGLPAQRPGKDQDMAAAILFVVG--CQYLNGQTVTVDGGYAIQVG------------------------- ->tr|A0A0D2ULP9|A0A0D2ULP9_CAPO3 LtxD OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_006400 PE=4 SV=1 -LPGALEEQGKQASLFKRLGTPDDIADLVDFLVGPTGGWITSQSVHTSGGVSFS--------------------------- ->tr|A0A0N0ZWA6|A0A0N0ZWA6_9FLAO Uncharacterized protein OS=Chryseobacterium indologenes GN=AOB46_07775 PE=4 SV=1 -MDERMKDMILSGYPLKEKLEGGDVAQVIDLCI-NGGKHFNGNHLFVDASHF----------------------------- ->tr|A0A0I9S977|A0A0I9S977_BACFG Uncharacterized protein OS=Bacteroides fragilis GN=EE52_0211930 PE=4 SV=1 -VDERILEQMVKDHPLKKLLTPEEVAQNIKFFV-DASQQVNGVKLQINAGTQ----------------------------- ->tr|A0A1H5VX06|A0A1H5VX06_PRERU Acetoacetyl-CoA reductase/3-oxoacyl-[acyl-carrier protein] reductase/17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoa -VEDFQLEQMKNAHPLKELLKPQEVAEVVCQLL-NTTQQLNGVEIPINAAQH----------------------------- ->tr|A0A232M1Q4|A0A232M1Q4_9EURO Uncharacterized protein OS=Elaphomyces granulatus GN=Egran_01981 PE=4 SV=1 ---AAFRQVWADRNPMRRMGTPQELTGPVVFLCSDiGSSYVNGADLVVDGECRSAAEAE-PTSPRRNLTSSTNLILNT---- ->tr|A0A126RPL0|A0A126RPL0_9SPHN Short-chain dehydrogenase/reductase SDR OS=Sphingobium sp. TKS GN=K426_15980 PE=4 SV=1 -IDTPTNRQDMPNEDFSKWVKAEAMAEVILFLASPAVRAVTGALIPVMRG------------------------------- ->tr|H2JLE3|H2JLE3_STRHJ Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Streptomyces hygroscopicus subsp. jinggangensis (strain 5008) GN=SHJG_1710 PE= ---DTIADRWERDAPLGWdRADVRRLTGPVLFLLSDLAATVTGEIVHADGGMHAVRMGV-GGQTFRKEAA------------ ->tr|A0A0H4WRH3|A0A0H4WRH3_9DELT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Myxococcus hansupus GN=A176_000862 PE=3 SV=1 ---KALEQGWGTQAPLGWsAKNShDLVARTACAMLSDWLPSTTGEMIHVDGGYHAIGAPP-VAPEADEAPA------------ ->tr|A0A1G0ZXJ7|A0A1G0ZXJ7_9BACT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Lentisphaerae bacterium RIFOXYC12_FULL_60_16 GN=A2498_06520 PE=3 SV=1 ---KRLMDWWQRMSPLPWdPDHDrAAVADAVGFLLGPGARRITGQVIHVDGGVSAVGGDW-LEHERINRPE------------ ->tr|A0A1Y0HHY0|A0A1Y0HHY0_9PROT Enoyl-[acyl-carrier-protein] reductase [NADH] OS=Sulfurospirillum sp. SL2-1 GN=Sdiek1_0535 PE=3 SV=1 ---RMILNWNEINAPLRKnVTT-DEVGNSGMYLLSDLSSCVTGEVHYVDAGYSIMGMGM-DETDAEGHTV------------ ->tr|A0A0C3FE19|A0A0C3FE19_9HOMO Uncharacterized protein OS=Piloderma croceum F 1598 GN=PILCRDRAFT_824835 PE=4 SV=1 --PTHKIQFIANIHPQKRMGLPTDIAPMIAFLASPEAAWISGQNIHINGVISSISPR------------------------ ->tr|K0C1G5|K0C1G5_CYCSP Short-chain dehydrogenase family protein OS=Cycloclasticus sp. (strain P1) GN=Q91_1122 PE=4 SV=1 --PDVVLDEIRQQSAIHAFTLPEQVAWGICLLLAPEADAMAGSSLMLDSG------------------------------- ->tr|F3L0K5|F3L0K5_9GAMM Putative short chain dehydrogenase OS=gamma proteobacterium IMCC3088 GN=IMCC3088_941 PE=4 SV=1 --IGEVLEQMASESTLKELTSVESIVWGISVLLDPNARAMAGSTLFMDSG------------------------------- ->tr|A0A084G9E6|A0A084G9E6_9PEZI Putative short chain protein OS=Scedosporium apiospermum GN=SAPIO_CDS4163 PE=4 SV=1 -FPEERLNAAIKANKLERFATVEDVAEQVKTFVV--SKSATGQNAIIDSGFSL---------------------------- ->tr|M7SI33|M7SI33_EUTLA Putative short chain protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_7044 PE=4 SV=1 -FPEERLAMVKEANKLKRFTTMEDVAEQVRTFVV--SKTVTGQNTIIDAGFSL---------------------------- ->tr|A0A094A0X8|A0A094A0X8_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. VKM F-3775 GN=V491_03310 PE=4 SV=1 --DEARAASILSRIPAGRWGKAEDFGGVVVWLAGAGSAHIDSVHLPSLDLSLSPVQYN----------------------- ->tr|A0A1A0XKF0|A0A1A0XKF0_9ACTN Uncharacterized protein OS=Gordonia sp. 852002-50816_SCH5313054-c GN=A5788_19385 PE=4 SV=1 --------------------AADDVAKAAVHIVASDREDLHGQCLSFDGDTLAVWT------------------------- ->tr|A0A1E4GZE3|A0A1E4GZE3_9CAUL 3-hydroxyacyl-CoA dehydrogenase OS=Phenylobacterium sp. SCN 70-31 GN=ABS78_06285 PE=4 SV=1 --------------------RADQPARFSVAMVTPAAAHVSGQIFGSSGENIILYS------------------------- ->tr|A0A1E3R5F1|A0A1E3R5F1_9MYCO Uncharacterized protein OS=Mycobacterium holsaticum GN=BHQ17_24375 PE=3 SV=1 --------------------PPELCSPAAAFLAHESCPLN-GEVLMAGMGGVSRLA------------------------- ->tr|G8YDN2|G8YDN2_PICSO Piso0_002838 protein OS=Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL Y-12695) GN=Piso0 --------SYDKTILNPPMEIpkdiavaLINITNSTIMVILYGVYNKHFHINPVYMNPW----------------------------- ->tr|J5E7W1|J5E7W1_9MYCO Dehydrogenase OS=Mycobacterium colombiense CECT 3035 GN=MCOL_V220251 PE=3 SV=1 -------EAIALSNGLADWANRTKsVTASCSSHPMHRASVRaRPCTCMVPPAPP----------------------------- ->tr|A0A1F8A5A3|A0A1F8A5A3_9EURO Short-chain dehydrogenase OS=Aspergillus bombycis GN=ABOM_004989 PE=4 SV=1 --------KMQYYGGMRDWPTPRSsAGLMCtcSLMVLhtrPVSIFR---LLVL---------------------------------- ->tr|A2SW61|A2SW61_9MYCO Putative dihydrodiol dehydrogenase OS=Mycobacterium sp. CH-1 GN=phdE PE=3 SV=1 -----IADIMSTTNPLQYAQQPADHAGLYLLLASADnSRAVTGVVINSDGGLGVRGLNQ----------------------- ->tr|A0A0K1JC81|A0A0K1JC81_9RHOO TodD OS=Azoarcus sp. CIB GN=AzCIB_4413 PE=3 SV=1 -----LSELLESVLPIGRMPDVREYTGAYVFFANHGdAAPATGAVLNYDGGMGVRGLFS----------------------- ->sp|Q7N4V7|HCAB_PHOLL 3-phenylpropionate-dihydrodiol/cinnamic acid-dihydrodiol dehydrogenase OS=Photorhabdus luminescens subsp. laumondii (strain DSM -----SLESLSAILPLQFIPQPKDFTGPYVMLASRAnNRTLTGVMITADAGLSIRGIRQ----------------------- ->tr|A0A0Q6JRN1|A0A0Q6JRN1_9NOCA Uncharacterized protein OS=Rhodococcus sp. Leaf258 GN=ASH03_19375 PE=4 SV=1 -----YRQQFEWLAPLQHMPTPEEYGPLYAFLASRHNTVMTGQTVLADSGSLNRALIS----------------------- ->tr|A0A0J5Q5F4|A0A0J5Q5F4_9RHOB Uncharacterized protein OS=Puniceibacterium sp. IMCC21224 GN=IMCC21224_1574 PE=3 SV=1 -----LDDLMKQILPLEKAFYADEYAGAYVFFADRNdNGPATGAVLNFDGGIGMRGFMS----------------------- ->tr|A0A1A3JTE3|A0A1A3JTE3_9MYCO 3-(Cis-5,6-dihydroxycyclohexa-1, 3-dien-1-yl)propanoate dehydrogenase OS=Mycobacterium sp. 1165549.7 GN=A5626_01875 PE=4 SV=1 -----RAAEVAARTPLHVALTGEDHAFSYVFLTSDRTRGITGETVRPDGGFGLGAPTS----------------------- ->tr|T0J059|T0J059_9SPHN Uncharacterized protein OS=Sphingobium ummariense RL-3 GN=M529_21510 PE=4 SV=1 -----FMAMIRKVTLLDHLPTGAEYGPAYALLADPKQRILTGEIIMADQGLANRPIIS----------------------- ->tr|O69366|O69366_RHOER 2,3-dihydroxy-4-phenylhexa-4,6-diene dehydrogenase OS=Rhodococcus erythropolis GN=bphB PE=4 SV=1 -----IGEVMKQRSALHFEPAPEDYVAAYVLLAAKSqSRTVTGSVFDVSSFGTPTRPSG----------------------- ->tr|N1LZ45|N1LZ45_9NOCA 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase OS=Rhodococcus sp. EsD8 GN=EBESD8_9760 PE=4 SV=1 -----IRQMVRDNGALQIEVEPDDYVGAYLYLACRDdSATVTGTVVDVSSWGTPKRTDA----------------------- ->tr|A0A1Q5Q035|A0A1Q5Q035_9ACTO 3-(Cis-5,6-dihydroxycyclohexa-1, 3-dien-1-yl)propanoate dehydrogenase OS=Actinomyces nasicola GN=BSZ39_11395 PE=4 SV=1 -----HTGPPNPYLPLPDAPtDPSAYVAPFLMLADPRaSAMITGEIIRADGGLAARGFYP----------------------- ->tr|A0A1V4PU73|A0A1V4PU73_9ACTN 3-(Cis-5,6-dihydroxycyclohexa-1, 3-dien-1-yl)propanoate dehydrogenase OS=Gordonia sp. i37 GN=B1964_23340 PE=4 SV=1 -----GPEDMAKMGGMKFFPTAQDYVPEYLMLAS-PeSRVANGVIFETHGMLVPPPLGH----------------------- ->tr|A0A198ZL61|A0A198ZL61_ECOLX Dihydromonapterin reductase OS=Escherichia coli GN=A6I93_11755 PE=4 SV=1 --DAEYRQQALNKSLMKTAPGEKEVIDLVDYLPV--ALSPDAVSHLMAVVICV---------------------------- ->tr|A0A191ZIG0|A0A191ZIG0_9GAMM Uncharacterized protein OS=Halothiobacillus sp. LS2 GN=A9404_09950 PE=4 SV=1 --DTSYRKQRLAQNLLPFEPGAGVICHTIDFLMA--CPAIDATTIRVDNGHQG---------------------------- ->tr|A0A0X3T6X0|A0A0X3T6X0_9GAMM Short-chain dehydrogenase OS=Thiomicrospira sp. WB1 GN=AVO41_08085 PE=4 SV=1 --SESLKQTRLAENAIPEPIGLAQIWQSVSYLMQ--SPAVTGTRLEVGQLQRE---------------------------- ->tr|A0A166GT79|A0A166GT79_9GAMM Short-chain dehydrogenase OS=Thalassolituus sp. HI0120 GN=A3759_06635 PE=4 SV=1 --NEAYRNKVLSQSLIKHELGYQAIVEACDYLAN--SHAVCGNVMRVDGGRFV---------------------------- ->tr|A0A1A6KJF7|A0A1A6KJF7_9VIBR Dihydromonapterin reductase OS=Vibrio cyclitrophicus GN=A9265_00210 PE=4 SV=1 --DEAYKTKALKKALIPAEAGFEEVIDGIKFVLA--SHYMTGRTLHLDGGRHL---------------------------- ->tr|W3WSH1|W3WSH1_9PEZI Uncharacterized protein OS=Pestalotiopsis fici W106-1 GN=PFICI_12192 PE=4 SV=1 -----YAVKAAKRCTAGRGGRPEEIAGPCIMLASKAGGYMNGGFLMIEGGRFMGASIH----------------------- ->tr|X8FKB4|X8FKB4_MYCUL Enoyl-(Acyl carrier ) reductase family protein OS=Mycobacterium ulcerans str. Harvey GN=I551_0601 PE=4 SV=1 -FTAQIRQTMREDRPLKREGTPEDIAEAALYFAGERSRYVTGPFFPWMVGRW----------------------------- ->tr|A0A0U1A6S9|A0A0U1A6S9_9MYCO Putative short chain dehydrogenase/reductase OS=Mycobacterium abscessus GN=sucB PE=4 SV=1 ------ADMSGGTFTLTNIGVFGVDAGTPIINPGEAAILALGSVAKRPWVVNGELAVR----------------------- ->tr|A0A1N2N7G3|A0A1N2N7G3_9MYCO 3-ketoacyl-(Acyl-carrier-protein) reductase OS=Mycobacterium abscessus subsp. abscessus GN=SAMEA2275679_06194 PE=4 SV=1 ----QARELIGDLPENERDATGEDIARVISFLSDDNSAFINGSIIPVTGGKDILGKAY-RL-------------------- ->tr|A0A225UEE2|A0A225UEE2_9STRA Uncharacterized protein (Fragment) OS=Phytophthora megakarya GN=PHMEG_00039959 PE=4 SV=1 ------FENVKEEVPTERLGEDSDMAGGAIFLASKASAWISGQVITCDGGMVGAAETG-----LISDIPRAKITINTMS-- ->tr|A0A0F4GQU9|A0A0F4GQU9_9PEZI Uncharacterized protein OS=Zymoseptoria brevis GN=TI39_contig350g00024 PE=3 SV=1 ---DKAMDTLLSGQPSGRVGTPEDFAGLVLFLSSMGAAHMTGNVLEVDGGSTLSGFRG--KVKRKADQKLCELL------- ->tr|A0A1C7MRI6|A0A1C7MRI6_GRIFR 3-oxoacyl-[acyl-carrier-protein] reductase FabG OS=Grifola frondosa GN=fabG_1 PE=3 SV=1 -------------FPLEDRPRPTRPLVPYSFWRRPLPPLSQDIRSRSPADKASEVWT------------------------ ->tr|A0A072PQM6|A0A072PQM6_9EURO Uncharacterized protein OS=Exophiala aquamarina CBS 119918 GN=A1O9_00376 PE=4 SV=1 --SPTSREAAVRAVPLQRFGLVKDVADATAFLFGDTGNFVNGTCLDVDGGAWRVQGAQ----------------------- ->tr|A0A0E9NQX5|A0A0E9NQX5_9ASCO Uncharacterized protein OS=Saitoella complicata NRRL Y-17804 GN=G7K_6340-t1 PE=4 SV=1 --DDSRAKGILERIPAARWGTPEDFKGPVVFLASGASDYMCGEVMVVDGGWMGRQHSVTQLNILNMTKPTVLLLGKID--- ->tr|A0A0D5C4M9|A0A0D5C4M9_9ARCH Short-chain dehydrogenase/reductase SDR OS=Candidatus Nitrosopumilus adriaticus GN=NADRNF5_2106 PE=4 SV=1 ----ENVQEFVKSLPMKRLGEPDEIGNFVKAIIENKIKYLSGVTINFDGANS----------------------------- ->tr|H0YSD6|H0YSD6_TAEGU Uncharacterized protein OS=Taeniopygia guttata PE=4 SV=1 -MPQDLVDAFKP----------EYVAPLVVWLCHescaengslfeVGAGWIGKLRWERSLgaivrG------------------------------- ->tr|A0A1Q3NNU8|A0A1Q3NNU8_9GAMM Short-chain dehydrogenase OS=Acinetobacter sp. 38-8 GN=BGO19_14365 PE=4 SV=1 ---EQWLEGAAQSTMLHRLPTLSDVAETVTFLSSDYAHAMTATIVNMTAGATI---------------------------- ->tr|A0A1V0YU81|A0A1V0YU81_ACINO Short-chain dehydrogenase OS=Acinetobacter nosocomialis GN=B7L44_13430 PE=4 SV=1 ---GQWLEGAAQSTMLKRLPTLSQVAETVAFLASEHANSMTATVVNMTAGTII---------------------------- ->tr|A0A1W2FUY8|A0A1W2FUY8_KIBAR NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family OS=Kibdelosporangium aridum GN=SAMN05661093_09132 PE=4 ---PEWAGARqsItDASPLKRAATMADVGNVAAFVASDKGRSITSTQVNISVGACY---------------------------- ->tr|A0A0W7VL30|A0A0W7VL30_9HYPO Short chain dehydrogenase OS=Trichoderma gamsii GN=TGAM01_06743 PE=3 SV=1 -MHKEGLNAIKEAHPKTINVPISHVARYAAFLSEDGiGQSSNGGCVTITGNWP----------------------------- ->tr|T0KDK0|T0KDK0_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_10392 PE=3 SV=1 -FHKEGLAVVVS-tfntvhgdpaKQGWNfgWSPLEQVAKTVLVLCSDGMNTINGALVPTDMGWT----------------------------- ->tr|A0A166TX75|A0A166TX75_9PEZI Short-chain dehydrogenase (Bacilysin biosynthesis oxidoreductase) OS=Colletotrichum tofieldiae GN=CT0861_07414 PE=3 SV=1 -FHQEGVAMVSS-tfntvqgdtaQRGWNfgWSPLNQVSKTVLSLCADGIHTINGALVPTDMGWT----------------------------- ->tr|G4MQV9|G4MQV9_MAGO7 Short chain dehydrogenase/oxidoreductase OS=Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) GN=MGG_04738 PE=3 SV= -IHQEAWARASK-vml--AADmkPISMETLAGYCVKLAEDNCSLFNGSCVTVDGGFS----------------------------- ->tr|A0A135UQF8|A0A135UQF8_9PEZI Short chain dehydrogenase OS=Colletotrichum nymphaeae SA-01 GN=CNYM01_12706 PE=3 SV=1 -VNQAGMAKVTAGMPEYKrgetGLDPAAVAKYCVFLTDKDiASSANGSCVVLNRNWP----------------------------- ->tr|A0A0F4Z1Z9|A0A0F4Z1Z9_TALEM Short chain dehydrogenase/oxidoreductase OS=Rasamsonia emersonii CBS 393.64 GN=T310_1565 PE=3 SV=1 -VNTEGFQLNER-lrg--GVGmqMVDLSDVAELALYVCTAEsAKIINGAIIPGDHGWT----------------------------- ->tr|U7Q340|U7Q340_SPOS1 Uncharacterized protein OS=Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) GN=HMPREF1624_02641 PE=4 SV=1 ------QQFASVMkvn--EMSvgFSDTGRLGRLVLFLCGEDGQDINGAVIQVDRGWT----------------------------- ->tr|T0M5N1|T0M5N1_COLGC Uncharacterized protein OS=Colletotrichum gloeosporioides (strain Cg-14) GN=CGLO_00856 PE=3 SV=1 -VNQEGMMKTVAAQPEYKrgetGLDPAAVAKYCIFLTDKDiASSANGSCITFNKNWP----------------------------- ->tr|A0A0M9VTX0|A0A0M9VTX0_9HYPO Putative oxidoreductase OS=Escovopsis weberi GN=ESCO_001009 PE=4 SV=1 ---KERIDISLR----IYseesFVEEYAAAKHIASICEGDnGKMLNGSTINMCGNWP----------------------------- ->tr|W6Q838|W6Q838_PENRF Short-chain dehydrogenase/reductase SDR OS=Penicillium roqueforti (strain FM164) GN=PROQFM164_S02g002307 PE=3 SV=1 -MHMGGYEKMIG-vln--AIQapPVDVNEVAGFCVNMTYGKgAGQINGATIAIDNGWT----------------------------- ->tr|A0A0B7JJL3|A0A0B7JJL3_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000000904_1 PE=3 SV=1 -NDTEGLNLLMG-ncp--GLKdgsaMVPLDKMSSLIMFLSSDSASSLNGQILNADNGAV----------------------------- ->tr|W9VU69|W9VU69_9EURO Uncharacterized protein OS=Cladophialophora yegresii CBS 114405 GN=A1O7_06544 PE=4 SV=1 -PDKVGLDTVMP---TMAtqcgNCDPIDAANAIVFLATA--VGLNGSELRIDKGWS----------------------------- ->tr|A0A0B7KBQ5|A0A0B7KBQ5_BIOOC Uncharacterized protein OS=Bionectria ochroleuca GN=BN869_000010582_1 PE=3 SV=1 --NMEVLGKMKG-flpGYPCIrgnsPPELTT--RIDIEQSFRD-----G--------------------------------------- ->tr|A0A0U0QU74|A0A0U0QU74_MYCTX Short chain dehydrogenase/reductase oxidoreductase OS=Mycobacterium tuberculosis GN=acr1_1 PE=3 SV=1 --PADMPPPFRSLTPIPVhwvaaaVLDGVAXXXXCSWWvTRSRRGTATGWSACSRArySVA----------------------------- ->tr|A0A1F8R0W6|A0A1F8R0W6_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_58_14 GN=A2W36_05730 PE=3 SV=1 --VKR---KTGRTTPAALrl--DAAEVAQAVLSIvRRPRRGLVIPWPMRFSVwlNVL----------------------------- ->tr|A0A1F9DAW1|A0A1F9DAW1_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_16_47_11 GN=A2157_12185 PE=4 SV=1 --DIG-------KVP--RrfIHWPEEVASRLVQAiRKDRQWDYSDYATRFSAwfGTL----------------------------- ->tr|A0A1Q5M6F0|A0A1Q5M6F0_9ACTN Uncharacterized protein OS=Streptomyces sp. CB02488 GN=AMK09_33735 PE=4 SV=1 --TP----PTADQLAHA--LQPEDVAAMVAAIlQLPPRAYVPELMLCPSRl-------------------------------- ->tr|Q0CGD5|Q0CGD5_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_07257 PE=4 SV=1 -MTDEMRQARINQNLLKQEGTGWDVGYAILFLCSKEAKWITGLIMPVDGGTTAGKADR----------PALK--------- ->tr|Q9AQ15|Q9AQ15_BRASW Nitrogen fixation protein FixR OS=Bradyrhizobium sp. (strain WM9) GN=fixR PE=4 SV=1 -MSPDTEAHFVRKIPLWRVVHPRRSRRSFS-------SYVQMRQVMSLAPK------------------------------ ->tr|A0A071LVC6|A0A071LVC6_9ENTR Short-chain dehydrogenase OS=Mangrovibacter sp. MFB070 GN=DT73_10535 PE=4 SV=1 -IDKPIEEIGSKLHMKGRIINPQEIADAIYLLSLPEASAINGSTVMVDDGYASF--------------------------- ->tr|A0A0R1ZY10|A0A0R1ZY10_9LACO Short chain dehydrogenase reductase family oxidoreductase OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL001891 -LGDFAAAAGGKLHMKGRILEPEEIANTIYLVSLPEASAINGTTVFADDGYTAF--------------------------- ->tr|A0A133KS62|A0A133KS62_BACCO Oxidoreductase, short chain dehydrogenase/reductase family protein OS=Bacillus coagulans GN=HMPREF3213_01802 PE=4 SV=1 -IQAYKDagmtQKMTEQQMRKKLIRPEAIANAVYLLTLEEADVINGSVVMLDDGYASF--------------------------- ->tr|A0A090GQA7|A0A090GQA7_9RHIZ Uncharacterized protein OS=Mesorhizobium sp. ORS3359 GN=MPLA_680055 PE=4 SV=1 ------KQAAVANIPIGEMALPAEVVELVAFVMRPSQASVNGATLDVDGGSYDEHRIG-KLG------------------- ->tr|A0A0B2VP39|A0A0B2VP39_TOXCA Dehydrogenase/reductase SDR family member 4 OS=Toxocara canis GN=DHRS4 PE=3 SV=1 ---EQELKKLCAMVPAGRIGQPRDCAGIVSFLLSDRAKYITGENTLVTGGVCDMWGVA------RRCAPSLK--------- ->tr|A0A0C5XD27|A0A0C5XD27_NOCSI 3-oxoacyl-[acyl-carrier protein] reductase OS=Nocardioides simplex GN=KR76_23185 PE=4 SV=1 --RGAAEHALRVRHPSSAtYADVGAVVRAVEQLVAEPGLDRTGAVVDVSAGLAAT--------------------------- ->tr|A0A1A2Z161|A0A1A2Z161_9MYCO 3-ketoacyl-ACP reductase OS=Mycobacterium sp. E796 GN=A5706_04110 PE=4 SV=1 ---EAIVQRATRVNPIPEpWLEAEDVTRAVVHLVTDPGVLT-GVVMEIGLGSSAR--------------------------- ->tr|A0A0Q9R5S0|A0A0Q9R5S0_9ACTN Short-chain dehydrogenase OS=Nocardioides sp. Soil796 GN=ASH02_20205 PE=3 SV=1 -----------------DVYHPGNVSPLVGWLLTEG-CPENGSVWYAKGGEIRRFAGW-SYEWT----------------- ->tr|A0A0C1UQU9|A0A0C1UQU9_9ACTN Short-chain dehydrogenase OS=marine actinobacterium MedAcidi-G2A GN=MB53_05280 PE=4 SV=1 -----------------DDKSPDNVSPLVAWLVSSD-CDITGRTFEVTGGQLNVCDGW-QHGPV----------------- ->tr|A0A1V2KV17|A0A1V2KV17_9ACTN Short-chain dehydrogenase OS=Frankia sp. CcI49 GN=CcI49_04840 PE=4 SV=1 -----------------HAMDPSNSSPLVAWLASDEADHVTGQVIRSIEDRIIWMQGW-KERKV----------------- ->tr|A0A1X0D5T3|A0A1X0D5T3_9MYCO 3-oxoacyl-ACP reductase OS=Mycobacterium insubricum GN=BST26_15140 PE=4 SV=1 -----------------DPLSPEHVVELVRYLASPASDAVNAQLFVVYGPQVAMIAAP-TVAGR----------------- ->tr|A0A1S3ZTM8|A0A1S3ZTM8_TOBAC short-chain type dehydrogenase/reductase-like isoform X1 OS=Nicotiana tabacum GN=LOC107790362 PE=4 SV=1 --TEEMIKRVIDECPNGRLGQTEDVAPVVGFLAVYDGCSSLNQIIRGFEFELW---------------------------- ->tr|A0A087NFH4|A0A087NFH4_9SPHN 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinC OS=Sphingobium sp. ba1 GN=IL54_3304 PE=4 SV=1 -SGKDVXXXX---RPQQDYPAATVVEYCSAVLTPKASS----SRLHQRCGRTPDR-------------------------- ->tr|A0A1A1Y0J4|A0A1A1Y0J4_9MYCO Short-chain dehydrogenase OS=Mycobacterium sp. ACS4331 GN=A5727_06365 PE=4 SV=1 -WL-DFGADYR-ESVGVAAATPMEQAYPLLFLCSDAAKVVTGITMVTDSGYLSAG-------------------------- ->tr|A0A1A3PMH2|A0A1A3PMH2_9MYCO Short-chain dehydrogenase OS=Mycobacterium sp. 1245111.1 GN=A5658_07820 PE=4 SV=1 -WL-DFGADYR-AKVGVAAATPMEQAYPLLFLCSEAASVVNGITLVTDSGYLSAG-------------------------- ->tr|A0A0W0FW88|A0A0W0FW88_9AGAR Putative short-chain dehydrogenase OS=Moniliophthora roreri GN=WG66_6919 PE=3 SV=1 -------------SPLKRPGRKEEIAAVDLYLSFCWRLVHEWYHYSS---------------------------------- ->tr|M7SPB5|M7SPB5_EUTLA Putative short-chain dehydrogenase protein OS=Eutypa lata (strain UCR-EL1) GN=UCREL1_6707 PE=3 SV=1 -------------FTTKRWNKPQEISSASIPCPT--LSVQ----------------------------------------- ->tr|R4XL16|R4XL16_TAPDE Uncharacterized protein OS=Taphrina deformans (strain PYCC 5710 / ATCC 11124 / CBS 356.35 / IMI 108563 / JCM 9778 / NBRC 8474) -TPTKAAAALQSMLEFpNRFGNADEFGHLVKSMIE--NTYVNGDVYNISGASRL-----GKL-------------------- ->tr|A0A0L0VV94|A0A0L0VV94_9BASI Uncharacterized protein OS=Puccinia striiformis f. sp. tritici PST-78 GN=PSTG_03874 PE=4 SV=1 -ISPAVRDNLLKTVEYpFRFGDPQEFSSLVMECIR--NTYLNGTSVLFSHIQLALLSrqSYGS--------------------- ->tr|A0A0Q5YBF4|A0A0Q5YBF4_9BRAD 3-hydroxy-2-methylbutyryl-CoA dehydrogenase OS=Bradyrhizobium sp. Leaf396 GN=ASG57_15880 PE=3 SV=1 -MPPKVSQSiVDRMILYpNRMGQPHEFASLVKHIAE--NAYLNATTISIDAGARMQP--R----------------------- ->tr|A0A087NA52|A0A087NA52_9SPHN 3-hydroxyacyl-CoA dehydrogenase OS=Sphingobium sp. ba1 GN=IL54_1418 PE=3 SV=1 -LPPDLVEELVDGAEFpKRAGRAEEFADAALFLIR--NPYINAEVLRLDGGARPPARtrWTAPA-------------------- ->tr|A0A1J4MF64|A0A1J4MF64_9CRYT Uncharacterized protein OS=Cryptosporidium ubiquitum GN=cubi_00844 PE=3 SV=1 -SMSEKISStLLKS-IPlGRFGVPNEFAETVINvGIK--SEYISGEIVYLDGAWRPPFItsGSIKR-------------------- ->tr|A0A1Z5T470|A0A1Z5T470_HORWE Uncharacterized protein OS=Hortaea werneckii EXF-2000 GN=BTJ68_10651 PE=3 SV=1 -MSDKVRKSLEGVFEFpKRPGQGKEFAMMVRSCVE--NTMLNGECVRLDGATRMPS-KM----------------------- ->tr|K2DDM2|K2DDM2_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_29C00372G0001 PE=4 SV=1 --NPGLLEAVKHYAPLKKLIAPTEVAKYIIWLVNGGCHAVSGSVVDFDPGYTINRW------------------------- ->tr|L8WLX6|L8WLX6_THACA Uncharacterized protein OS=Thanatephorus cucumeris (strain AG1-IA) GN=AG1IA_08636 PE=4 SV=1 -------------IPFERSGKgksDIDMGGLALFLSSPAAYYVHGQIISIDGGFGAVNPTH--------VPPADGNIPTHHTP- ->tr|A0A1M5A568|A0A1M5A568_9BACL Uncharacterized protein OS=Seinonella peptonophila GN=SAMN05444392_1125 PE=4 SV=1 ---QEVLDQFTSTSPAKRIGTPEDVANLIVYLGSEANIFV----------------------------------------- ->tr|C1BDQ3|C1BDQ3_RHOOB Putative oxidoreductase OS=Rhodococcus opacus (strain B4) GN=ROP_pROB02-00930 PE=4 SV=1 -IEPGYHERHLAYTALGDLATPEDLGEGIAFFLEPQSDAVTGEVMRVAAGV------------------------------ ->tr|L7UK23|L7UK23_MYXSD NAD-dependent epimerase/dehydratase OS=Myxococcus stipitatus (strain DSM 14675 / JCM 12634 / Mx s8) GN=MYSTI_05527 PE=4 SV=1 --KPELRASIASKSTFGRLITPEEIAHVLYFCAT--TATVNGAVLHANLGQ------------------------------ ->tr|F3KYM2|F3KYM2_9GAMM Oxidoreductase OS=gamma proteobacterium IMCC3088 GN=IMCC3088_1975 PE=4 SV=1 --NTEVINAIGALNSFSRLVQPNEIASGVVFCHD--NPAINGSVFHLNLGQ------------------------------ ->tr|A0A085WC68|A0A085WC68_9DELT Oxidoreductase OS=Hyalangium minutum GN=DB31_1397 PE=4 SV=1 --DAKTLEVLRSITGEGRLIEPQEIARVIAFAAD--HPVLNGTLIHANLGQ------------------------------ ->tr|A0A0A8E547|A0A0A8E547_9GAMM Uncharacterized protein OS=Allofrancisella guangzhouensis GN=SD28_03255 PE=4 SV=1 --GGRHIDQAIENVAMKRIIDPKEIANFITYCVE--TPIVNGAVLHTNLGY------------------------------ ->tr|A0A1J4XB49|A0A1J4XB49_9PROT Uncharacterized protein OS=Proteobacteria bacterium CG1_02_64_396 GN=AUJ55_05285 PE=4 SV=1 --IPEHMIPVEDVT------------AAIAYILdC--SPNTAPSE--IRLRP------------------------------ ->tr|A0A0D2NFS7|A0A0D2NFS7_9CHLO 2,5-dichloro-2,5-cyclohexadiene-1, 4-dioldehydrogenase OS=Monoraphidium neglectum GN=MNEG_3995 PE=4 SV=1 -------------NPIGRIARPEEVAEAVLWLCTS-ATYTTGSHLSLDGGADCGGQGVFVHTDVRDEAAVAALAEQIRSR- ->tr|Q0RLX8|Q0RLX8_FRAAA 3-hydroxyacyl-CoA dehydrogenase OS=Frankia alni (strain ACN14a) GN=FRAAL2831 PE=4 SV=1 -IPDRAAEALTKDAAFpKRMGRPDEYARLALAIVE--NPMLNGGTIRLDAGQRF---------------------------- ->tr|A0A0C9PYW6|A0A0C9PYW6_9HYME Scu_2 protein (Fragment) OS=Fopius arisanus GN=scu_2 PE=4 SV=1 -WSQEVKTRMINSGMTpKRIGHPTEIAHIIKCVIE--NHYINAENIRIDTGFRS---------------------------- ->tr|A0A0Q9W6J7|A0A0Q9W6J7_9BACI Uncharacterized protein OS=Bacillus sp. Soil768D1 GN=ASG99_13965 PE=4 SV=1 -LKDKGLTDLYKNCQMrKEFIEPEDIAGMVCllAMEE--ANVVNGSVVMLDDGLTG---------------------------- ->tr|A0A1B3PIA2|A0A1B3PIA2_9BURK Short chain dehydrogenase family protein OS=Acidovorax sp. RAC01 GN=BSY15_3288 PE=3 SV=1 -MPTKVSQnIIDNVILFpHRMGQAQEFGGLVRHVVE--NAYLNATTISLDAGVRC---------------------------- ->tr|A0A1E4HRR1|A0A1E4HRR1_9PROT 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (Fragment) OS=Rhodospirillales bacterium SCN 65-16 GN=ABS83_01865 PE=3 SV=1 -APENVKAALAASVPFpKRLGRPEEYAQVAQTMIT--CGYFNGEDVRIDGAIRM---------------------------- ->tr|A0A1X0I808|A0A1X0I808_9MYCO Uncharacterized protein OS=Mycobacterium paraseoulense GN=BST39_17335 PE=4 SV=1 -----LVNAMQTALPDLLLIEPKDVSNAVLFLISEAGRSFTGSVLKVDAGM------------------------------ ->tr|T0HDE8|T0HDE8_9SPHN Uncharacterized protein OS=Novosphingobium lindaniclasticum LE124 GN=L284_13070 PE=4 SV=1 -IPAEAVNHLADQTVANRYLSAEEVAQAFAFLCSDRASGISGDLHHVNGGGYFSLQY------------------------ ->tr|M2N8V6|M2N8V6_BAUCO Uncharacterized protein OS=Baudoinia compniacensis (strain UAMH 10762) GN=BAUCODRAFT_123932 PE=4 SV=1 -YSPEFVQKWQADNPLQRVPEPEECADIFVALAK--NLSMTGQQIPIECGWLLTHSH------------------------ ->tr|A0A094I3B7|A0A094I3B7_9PEZI Uncharacterized protein OS=Pseudogymnoascus sp. VKM F-4519 (FW-2642) GN=V501_02963 PE=4 SV=1 -YPEATIKFMEERAYLKKVTDLEDCAQSFIDTAR--NSSMTGQKIVVGGRAVSWKEW------------------------ ->tr|N1PLT5|N1PLT5_DOTSN Uncharacterized protein OS=Dothistroma septosporum (strain NZE10 / CBS 128990) GN=DOTSEDRAFT_130457 PE=4 SV=1 -YGEERINGLKNAAALKKETEMGDCAQMFVDIAK--NTSMTGQAVHVGQSVSIWANG------------------------ ->tr|U4L2C8|U4L2C8_PYROM Similar to Granaticin polyketide synthase putative ketoacyl reductase 2 acc. no. P16543 OS=Pyronema omphalodes (strain CBS 1003 -FGEEKIKKATEKTKLGTLGSLEDCAEGYVYLAK--ADTVTGASLKIDGGAHEH--------------------------- ->tr|G0RWM3|G0RWM3_HYPJQ Predicted protein OS=Hypocrea jecorina (strain QM6a) GN=TRIREDRAFT_124136 PE=4 SV=1 -FPEEVIEGYKRISTLRDVVALDDCADAFVSLAK--NSAMTGQQIVVVDQSLAVIPK------------------------ ->tr|A1CE83|A1CE83_ASPCL NADP(+)-dependent dehydrogenase, putative OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 -FPPEKLQGFKNKAVLGKLPEVEDAAEAYVMLAK--NPSMTGQSIQIGKHSQASFYS------------------------ ->tr|B8LU00|B8LU00_TALSN Short chain dehydrogenase, putative OS=Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006) GN=TSTA_07 -FSEEYVENHINQTALKRVAELDDTADLYISLAK--NASITGQSLAVGESHFVHLFE------------------------ ->tr|W9X3T1|W9X3T1_9EURO 3-oxoacyl-[acyl-carrier protein] reductase OS=Cladophialophora psammophila CBS 110553 GN=A1O5_05399 PE=4 SV=1 -YSDERIQAVKNAAALKQETIVQMPISRLRKTRR--SQ--ASRLSLVSSGSWVLLAK------------------------ ->tr|G1XQ71|G1XQ71_ARTOA Uncharacterized protein OS=Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) GN=AOL_s00188g82 PE=4 SV=1 -FPQEAKDKYLGMTQTKKHVEAVDVADAFVFISQ--NVAMTGQKIVIDGGVVIQP-------------------------- ->tr|C4Y271|C4Y271_CLAL4 Uncharacterized protein OS=Clavispora lusitaniae (strain ATCC 42720) GN=CLUG_01212 PE=4 SV=1 -FPQEKVQQTVEASPIKKLADIDETAAQFILLCK--LATSTGTIVGIDGGIYV---------------------------- ->tr|D5GPB4|D5GPB4_TUBMM Uncharacterized protein OS=Tuber melanosporum (strain Mel28) GN=GSTUM_00011788001 PE=4 SV=1 -FPEEAIERTKERSKLKVAPTVEECADAFVLMAK--SSSMTSSTLKIDGGLYT---------------------------- ->tr|A3LSQ5|A3LSQ5_PICST Granaticin polyketide synthase putative ketoacyl reductase 2 OS=Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 1 -FPQDRIDKSKQISPINAIPDVEETAAQFVLLSK--LATSTGSIVAQDAGISL---------------------------- ->tr|A0A1A5ZTG0|A0A1A5ZTG0_9TREE Uncharacterized protein OS=Cryptococcus dejecticola CBS 10117 GN=I303_08432 PE=4 SV=1 -FTDAQIAAVKRINSLHQVTSIADVASAYVMLAQ--NGSMTGQTIEVSSGFRLGRD------------------------- ->tr|A0A1L9UGC5|A0A1L9UGC5_9EURO Uncharacterized protein OS=Aspergillus brasiliensis CBS 101740 GN=ASPBRDRAFT_31608 PE=4 SV=1 -FPAEAIERWTAKTALGKVPELEDTAQAYVMLAQ--NSSITGQEIQIAELTLQIPAS------------------------ ->tr|A0A1L9RMK3|A0A1L9RMK3_ASPWE Uncharacterized protein OS=Aspergillus wentii DTO 134E9 GN=ASPWEDRAFT_134832 PE=4 SV=1 -YGTDAIAKMKNGSILKQETLLEDCAEAFVSLSK--NTSTTGEHVLVDSGFLVGTST------------------------ ->tr|A0A1L7WN77|A0A1L7WN77_9HELO Related to cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase OS=Phialocephala subalpina GN=PAC_04112 PE=4 SV=1 -FTEEQRQGFKEMAKLKRITTPEEIAMTFVFAAK--NSGMTGERIRVDSGMVVV--------------------------- ->tr|A0A1U7LU95|A0A1U7LU95_9ASCO Granaticin polyketide synthase putative ketoacyl reductase 2 OS=Neolecta irregularis DAH-3 GN=NEOLI_002385 PE=4 SV=1 -FGEEKLKKHVASNALQKMTDLDDVAALYTMLAA--NESITGENFNVASTVL----------------------------- ->tr|A0A232LV83|A0A232LV83_9EURO Uncharacterized protein OS=Elaphomyces granulatus GN=Egran_04184 PE=4 SV=1 -FGQTQIEEWPDKLVLKRIVDLDDCAALYPAIAK--NSSMTGQSIQVDSGAIIR--------------------------- ->tr|A0A1Y1Y4L8|A0A1Y1Y4L8_9PLEO Short chain dehydrogenase/reductase OS=Clohesyomyces aquaticus GN=BCR34DRAFT_248418 PE=4 SV=1 -YPQETIDFVINKATLHHETDLQDTADVFVMLAR--NTSMTGAKVQIDAGLNIQG-------------------------- ->tr|A0A1Y2FGH8|A0A1Y2FGH8_9ASCO Uncharacterized protein OS=Protomyces lactucaedebilis GN=BCR37DRAFT_346765 PE=4 SV=1 -FDRQKMDWVTANTPTGAIATLEDCADAVHLLCA--NKSISGQTIVLDGGFTLR--------------------------- ->tr|A0A0N8P2E4|A0A0N8P2E4_9PROT Uncharacterized protein OS=SAR11 cluster bacterium PRT-SC02 GN=JI56_02095 PE=4 SV=1 -LNKRLRKKILNKIPSKKTGDVKNIFNAIQFLVD--SDYVNGSLIKIDGGY------------------------------ ->tr|A0A1Q5SKX7|A0A1Q5SKX7_9BRAD Uncharacterized protein OS=Bradyrhizobium sp. NAS80.1 GN=AC629_08705 PE=4 SV=1 -LDEEGRRRIAGRGTLRRLPEADDVASMVEYLLGEGGRNPTGTVLTVDAGNTA---------------------------- ->tr|C5FK54|C5FK54_ARTOC 3-oxoacyl-[acyl-carrier-protein] reductase OS=Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) GN=MCYG_02895 PE=4 SV=1 -LGEQFRNDTMQSIPLRRFGTIEEVADAAVFVVT--NQYANNCVLNLDGGLSA---------------------------- ->tr|A0A0C3BVY9|A0A0C3BVY9_HEBCY Uncharacterized protein OS=Hebeloma cylindrosporum h7 GN=M413DRAFT_79321 PE=4 SV=1 -Fv-----TEATCCGEYpRRPGRPEEFSHLVQSLFE--NEMMNGAVVRQDAA------------------------------- ->tr|A0A1X3HFG2|A0A1X3HFG2_9BRAD 3-hydroxyacyl-CoA dehydrogenase (Fragment) OS=Bradyrhizobium canariense GN=BSZ18_00155 PE=4 SV=1 -LNEEARASLGAQVPHpARLGDASEYGNLAVHIVE--NPM------------------------------------------ ->tr|F8TTM4|F8TTM4_9BACT Short-chain dehydrogenase (Fragment) OS=uncultured Acidobacteria bacterium C5 PE=4 SV=1 -FGEEFIEFASKLNLERQFVGVDEVASAIFGLCSGLMDGVSGQVIMVDRGGTFS--------------------------- ->tr|A0A077W3Z7|A0A077W3Z7_SALTM Uncharacterized oxidoreductase yghA OS=Salmonella typhimurium GN=yghA_2 PE=4 SV=1 -QPQEKVEKFGANAPLGRPGQPVEIAPLCHPGRSGEQLYVWsGLVF------------------------------------ ->tr|A0A1F3VAI5|A0A1F3VAI5_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYC1_FULL_39_130 GN=A2404_16800 PE=4 SV=1 -LSKQLKYDYLKHCSLRRYGKAIEVANMAVWFLEE-NSYITGKTIVLDGG------------------------------- ->tr|A0A1T1HT40|A0A1T1HT40_9PSED 3-oxoacyl-ACP reductase OS=Pseudomonas sp. MF4836 GN=MF4836_23300 PE=4 SV=1 -IPLLIREAGRRMNSLSQGGQAVDVAQTIAWLAHPASGGINGQVVRVCGQSLLG--------------------------- ->tr|A0A176I6L8|A0A176I6L8_9GAMM 3-oxoacyl-ACP reductase (Fragment) OS=Oleibacter sp. HI0075 GN=fabG PE=4 SV=1 -IPFMTREVGRRLNSLSQGGKPVDVAETIAFFGNPASNGVSGNVVRVCGQSLVG--------------------------- diff --git a/esm/examples/UniRef50_UPI0003674933.a3m b/esm/examples/UniRef50_UPI0003674933.a3m deleted file mode 100644 index 5244347..0000000 --- a/esm/examples/UniRef50_UPI0003674933.a3m +++ /dev/null @@ -1,2130 +0,0 @@ ->UniRef50_UPI0003674933 -MKKKEDILNLEHTLLPWMGRTMKVLDYFIGDFLNLKGIELTKVQWILLKKLNEQNGQPQQNLAFLTNRDKASLARLITTMEKKKLVERIPSKIDGRINHIFITKHGCEILQKSAPVIEKVVGCIQEGISPEEIETVIKVMQKVNNNINRASN ->tr|A0A1J5IWR0|A0A1J5IWR0_9PROT Uncharacterized protein OS=Zetaproteobacteria bacterium CG2_30_59_37 GN=AUK36_09885 PE=4 SV=1 -MENPQqqPVSGELGAIMPLIGFMSSHVRFHISRICSDAGHPLTPEEAGTLMIIRHFKGLPQTRLAVILGKDKAAVTRLMNALVKSGLVGRIPDEQDRRVVRAQITGLGEQAFIKLWPELTKLSDEALKDIPKQDLEQLSNVLRLINANLAA--- ->tr|K7SNK0|K7SNK0_9HELI Uncharacterized protein OS=Candidatus Sulfuricurvum sp. RIFRC-1 GN=B649_08095 PE=4 SV=1 ------------------TNLSAMAARNYLTRQLSLHGIDMTIEQFKVMVVLWKEGTSTQQNIADFVGKDKTSITRLIAGLEKRSLIGRATDENDKRCNLVTLTPQGIALEKPTMEVLQQANESLQKHFNPEELAITLRVLKQMCLSLN---- ->tr|G2H9E7|G2H9E7_9DELT MarR family protein OS=Desulfovibrio sp. A2 GN=DA2_2506 PE=4 SV=1 ------------------TFTTSRLMAAFLRRRMAQAGIDLTGEQWGVMVFVWNRGAIGQDELAHALCMDKTGMSRLLATMEGKGLVTRNPDPADARRRAVRATKQGDALKERCRAVAEEALVLLLKDVSPQDHATCMRVLATVKETLR---- ->tr|A0A238YWN1|A0A238YWN1_9DELT DNA-binding transcriptional regulator, MarR family OS=Desulfovibrio mexicanus GN=SAMN04488503_1042 PE=4 SV=1 ------------------ATQFSKAVLRRINQEFAAGGHAVTGEQWTALVHIWDAEGLTQQELGQRLIKDKTTIARLVAGLERQGYVRRKPGASDRRERLLALSERGRADMPVLAALVQGVLDQACAGIDAHELSLCRRVLARARQNLV---- ->tr|A0A212K2M8|A0A212K2M8_9BACT Putative MarR family transcriptional regulator OS=uncultured Dysgonomonas sp. GN=KL86DYS1_31248 PE=4 SV=1 ------------------IASVAAQLRRLAFRLISEKGLDITPEQWVILYYLWLDDGLSLSELTKKSKKDFANTTRIIDKLCTAKYVVKQKSITDSRSYNIFLLPRAESIRQEVITCWTEATAIFTNGLSEDEINIFLKLLAKVENNLS---- ->tr|K1Z1N7|K1Z1N7_9ZZZZ Transcriptional regulator, MarR family OS=groundwater metagenome GN=ACD_77C00282G0001 PE=4 SV=1 -----------------LVSKTSQKFKLELNRKLKKSGLDVSSDQWTVLMYLSDNNGPSQTDLAQKLYKDRANLTRILDLMEKNQLVERQRSSIDRREYNVFITEKGMSLIPQLKLIGDSVMEKALKGANAEEIIGIKHFLNKLFINLDN--- ->tr|A0A161LG42|A0A161LG42_9BACT MarR family transcriptional regulator OS=Paludibacter jiangxiensis GN=PJIAN_4298 PE=4 SV=1 -----------------LSGRVGDKIKRPFYKAFARECIAISSEQYAILACLVKQNMVTQQTLCGLTKKDKPNVTRLIDRLENKSLVQRIADAEDKRKKRICITEQGMLVYEKVNHIVSDMVSHAMKNIDEGQLVVFQDVLRHMMHNLSM--- ->tr|A0A1N7MZJ4|A0A1N7MZJ4_9BACI Transcriptional regulator, MarR family OS=Salimicrobium salexigens GN=SAMN05421758_1105 PE=4 SV=1 ---------------------ASRVMNARLNENFKKIGHTLTYEQWQIMSRLYGKEGQTQRMLAVSIERDEAGTSRLLGRMEKAGYIYRYVNPEDKRRNYIYPTEWARQEEEKLNRTALDTIDEACAGMTEEEKRSGQLFLEKIRNNLGSS-- ->tr|A0A1Y5GH82|A0A1Y5GH82_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 45_16_T64 GN=A9Q99_25160 PE=4 SV=1 ---------------------ISRYVNQWLERALSSTDT--SLQEFKIIGLLMGSDDITQKTLAEYLSVRPATLSVAITNLENKGYIQRVTSQEDKRVNYIRLTKNVDMEQG--VDILHGLEDKATKGITKKDLAVTQRVLNQIAQNLKED-- ->tr|A0A117T141|A0A117T141_9BACL Uncharacterized protein OS=Paenibacillus sp. DMB5 GN=AWJ19_10345 PE=4 SV=1 -----------SEKLSVIFYRVNRNYQYLMALH--LKPFQITPEQWNVLKYLQEQDGLTPKDLTYMADKDKTTITRIIETLVERGTVTKEMNPDDRRSFRIFLTDTGRELIREVQPIPDLVNKKVCRELSVEQIIGLKEMLYLMQTQI----- ->tr|Q7MS26|Q7MS26_WOLSU Uncharacterized protein OS=Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) GN=WS0847 P -----------KNSPGFWIGRIHHKLKNRMNQR--LKPYDLTAEQRLILLRLFEFGEMTQQQLCQKTFTEPSNITLTLRRMESHGYVRKKPHPKDKRASLIEATPKALSIQNELERIGLEITDSLLLEVDPSEKETLLRVLQAMYQKM----- ->tr|A0A010YSS6|A0A010YSS6_9BACL Transcriptional regulator OS=Saccharibacillus sacchari DSM 19268 GN=SacsacDRAFT_0185 PE=4 SV=1 -----------QDSIGFQLGVIYRKVSNRLAAN--LKDYDLTPEQWSVMCCICFKEGMNQKEIAERTVKDQPTVTRILNVLHRKGLIMRSSDRADRRAYLIYPTEKGRQVTEETSVIERHHNAAMIEDFSPEQLELLAEAFRKIERNA----- ->tr|M1PSV6|M1PSV6_DESSD Transcriptional regulator OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=UWK_02870 PE=4 SV=1 -----------RKPIGRLLYMTAQAMTLHAEKV--LKPYDMTVEQLHILKNMDENTALSHQELSKIVQKSAANVTRILDRLERKNYIRREKNPKDRRSILVLITAQGRDLVAEVSLVLEAFTKQLTRGITIEEQDLFTQILCTMQGNL----- ->tr|A0A0S2I4U6|A0A0S2I4U6_9BACT Salmolysin OS=bacterium L21-Spi-D4 GN=slyA PE=4 SV=1 -----------KKSLGLLSLAISKGLGNRLEQK--LKAqkINITADQWSVLSMLRHEGESSQKNISDVFGYDKVRVLRIVRNLEDRGILNKRVCSHDKRTRIVSLTSEGMSLYAKIHPIAEATINEATKSLSNREVRLYTEISQKIIMHL----- ->tr|M8DDE2|M8DDE2_9BACL MarR family transcriptional regulator OS=Brevibacillus borstelensis AK1 GN=I532_01995 PE=4 SV=1 -----------RDSLGHNLHRVGQLIREETAKA--L--gpFGITPEQWQLLVATAQTDGLTPSELGKRTLRDKTTISRILPGLLKKGWLKTEPHSQDARSYIVKMAPDKVKVIEETLEAVRDHFTQSVFaPFSKAEQDMFLSMVVRLRDHL----- ->tr|A0A173XS91|A0A173XS91_9FIRM Salmolysin OS=Mitsuokella jalaludinii GN=slyA_2 PE=4 SV=1 -----------DNTIGYMISRVARKIHYAVDEV--FKAYGITVEQWVALKTIAEYEPLCQKALAEKIEKNQNTVKALVTHLDDKGFIDRTPNPDDMRHMMLRTTERGRALVARLTELDEHKNFDFLGALSEAEQEDLRRMLRKIEARL----- ->tr|A0A1C0AUD3|A0A1C0AUD3_9PROT HTH-type transcriptional regulator MhqR OS=Arcobacter thereius GN=mhqR_2 PE=4 SV=1 -----------NKSLGFILNRTALASKNAFNQE--IKDYEISPEQWSVVYRVIKEPGISQKLVSDSTYKNQGNLTRMIDKLEKSDFLIKKQNSENRREIQLFPTKKAIDLSKPIIEHSTQHNNNMLDTFSTSEKEQLFNLLNKVYNNL----- ->tr|A0A1R0X1Z1|A0A1R0X1Z1_9BACL Uncharacterized protein OS=Paenibacillus odorifer GN=BJP51_25985 PE=4 SV=1 -----------MDNPGQLLIRVSLEMKKSLTKK--LLLYNVTAPQWAVLKDISIhLEGTTPAMIAERTYSDRPTITGILERLKAKGLLDIRDNPNDKRSNLVFITDSGMIIKSQIEVLSDEIMDNALKNISEQEMSTFMNVLKTIYLNI----- ->tr|A0A1Q7WIB2|A0A1Q7WIB2_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_20CM_3_68_10 GN=AUG43_03210 PE=4 SV=1 -----------EQQVSALVFHLGRELRTALDRR--LTShgLTSQQAALILLSRLLH--EPNPNKMAERLGTDTAGMTRLIDRLEKKGLIFRKTSPEDRRSIVIVLGPKSKHMLPRLIPEFRHVEDSVLDGFR----------------------- ->tr|A0A1T5BLS8|A0A1T5BLS8_9PROT Transcriptional regulator, MarR family OS=Arcobacter marinus GN=SAMN06295997_11474 PE=4 SV=1 -----------ENSLGFKISQTANRLNYQFVQL--LTQYDIAPEQRATLEIISNDNEVSQTKIASILGKNKTTICRSLNSLEKKGLIIRDCQIKDKRVNIIKLTQKGKDVLQASQNCVIEFRKKINSNLTKEEINKLFELLNKVSNTI----- ->tr|A0A1F3KA74|A0A1F3KA74_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_33_38 GN=A2W98_10055 PE=4 SV=1 ------------------VGRMMHMmFRVLKKRTGEq-ADVKLTIEQFGLLHAIsMKEEDVIQKDMAEMMGKDKSAILRIIDTLEEKELVRRVVDTNDRRKNFLMVTKKGEKVLEQCLKIEFELMEELQQGLSKSDLDTFYKVINHIRSRAEK--- ->tr|K4KI77|K4KI77_SIMAS MarR family transcriptional regulator OS=Simiduia agarivorans (strain DSM 21679 / JCM 13881 / BCRC 17597 / SA1) GN=M5M_02145 PE ---------HLHNSFAFWIGRLAQQMQEQFNRDL--KEHDISWHQWALLNVMLHGVAKTPAQAADAIGADRSTVTRMLDRLEKRGLTTREHDGLDRRVVKIALTKDAMALMTQLNQLAQAHQTQFLSELPSTEYRSLRGSLVKMLRAGGV--- ->tr|A0A150AFH7|A0A150AFH7_9BACT Uncharacterized protein OS=Flammeovirga sp. SJP92 GN=AVL50_22905 PE=4 SV=1 ---------EKRRRLTKIIAQVSRLGNYTLGRAFEREGLPISREQWDVLVMLWDKDGRAQQEFATFLLKNRASITSLIDNMEKNNLVTRVPNPNDKRSKLIYLTRKARDLKEQVVGIAQDAILSITKGIPLEDVEHAADLLTKCLENIVE--- ->tr|G4RFE5|G4RFE5_PELHB Transcriptional regulator, MarR family OS=Pelagibacterium halotolerans (strain DSM 22347 / JCM 15775 / CGMCC 1.7692 / B2) GN=KK ---------DYQAATPHWVNRLSFLIRAEVQQRFKAAGYAITAEEWAMLMLLWPNAPQSMGQLAAVSLRDRTTVTRLVDSMVAKGLLERTPAPNDRRSVLVDLGPKGRALEAPLTAIVGDFIAQATKGLSADEIARANAVLQKMTANILG--- ->tr|A0A1J4Y9F8|A0A1J4Y9F8_9PROT MarR family transcriptional regulator OS=Zetaproteobacteria bacterium CG1_02_55_237 GN=AUJ58_09410 PE=4 SV=1 ---------QLEQAIGLNVNRTAFLMTEEIARRFARHDYPLSAQDFGILFRLFKQGPRTQVEIAALMMRDKTTITRRIDGLVKKQLVERMPDPDDRRYFRVTLTEQGHRALEVMIPLVRDFQQEVLSDIPDEEKAITIRTLQQISEKLIK--- ->tr|A0A1R0WV32|A0A1R0WV32_9BACL MarR family transcriptional regulator OS=Paenibacillus odorifer GN=BSK60_09985 PE=4 SV=1 -----------------------------------FRPYNMTRSQWIAMYYIYTSESITQRELADKMSIKEPSVVRLLQKLESEGFLHRSGTHADKRVKQLELSDKGVQIYLDLLPVAEKFKDDTITNISEQDLQTFKNVLGVMVENAS---- ->tr|F2IDX4|F2IDX4_FLUTR Regulatory protein MarR OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_2531 PE=4 SV=1 ----------------YKIDRAIRTYRQFAQARLRSLGHQITIDQWLVIKCLIENPKIQQNEISEQVFKDAASVNRMINLLVESKYLKRKINKLDRRKMDILVTQKALDAIDAMDEVIPNNRSHALTGLTQEEMQIATKVMTQIATNCK---- ->tr|A0A136PBY2|A0A136PBY2_9BACT DNA-binding transcriptional repressor MarR OS=Chlorobi bacterium OLB5 GN=UZ05_CHB002000392 PE=4 SV=1 ----------------SNLEFTLKSYKKHLSSIFDKSSILITPDQWQVLDIIVNHKDIKYSEIAVISGKDIASVNRIIDLLNQKGYVSRQTDPNNRRRVILGVSNDGVKIHKRAGELINIESKKLLDGFKEKRIIKAGKDV------------ ->tr|A0A1N7ICK1|A0A1N7ICK1_9FLAO DNA-binding transcriptional regulator, MarR family OS=Chryseobacterium joostei GN=SAMN05421768_104115 PE=4 SV=1 ----------------YNIDKAIRSYRNYAQRQLKAHGFTITIDQWLIIKAILENPGITQNEIGDLVFKDNASVTRIIDLMVKSEYIIRHIHPDDRRKTNLEVTDSGKKVIKEVQNIVEKNRKAALKGVSKDELEVMYSALLTISENCL---- ->tr|A0A1D7V107|A0A1D7V107_9LEPT Uncharacterized protein OS=Leptospira alstonii GN=A0128_17685 PE=4 SV=1 ----------VKDAYGFLIVRSNRLFRLHFQRLCQRNDIDISQEQWFLLNKIAHSEGLTQGDLTDDLFGDKPNISRMVEKMEQKGWIRRVNDSTDNRILRLHLTKKGSATHERMVSIVGEERNKIYAGLSSKDFKDFERIIGILEKNL----- ->tr|A0A098F3P9|A0A098F3P9_9BACI MarR family transcriptional regulator OS=Bacillus sp. B-jedd GN=BN1002_03714 PE=4 SV=1 -----------NRHVGLLIRNADLSLANYIKK--QLEPFNLAPEQNLIMMMLWEKDGVSPNELVSCLKKDKGNIARMVASLEKKGYIKRVADPGDKRTFKIHLTEEGRRLECSVEPILQEATRTVTNGLSPEQVSQLQEMLTKIIDNLSG--- ->tr|A0A0Q4HCR7|A0A0Q4HCR7_9MICO Uncharacterized protein OS=Agromyces sp. Leaf222 GN=ASE68_09805 PE=4 SV=1 -----------SIEVGILLNQVHSVATERLNT--ALQPMNLTSRHAAVMFLIRD-GVETQRDLVRRLNTDKTGMVRMVDDLDRLGYVSRTPSTSDRRVTILTLTSAGEHALREAQQHTRRVADDVFRSVGSTELMELRSILSGVMGREIP--- ->tr|F8E9W7|F8E9W7_FLESM Transcriptional regulator, MarR family OS=Flexistipes sinusarabici (strain DSM 4947 / MAS 10) GN=Flexsi_1736 PE=4 SV=1 -----------EKDISMTLAKVFFGMKKIFTK--LWSEYDITPEQVGILTILWDEDGLSQHDIAKRSIKDAPSTARLISRLIDRGFVKCVTDRQDRRCTNVFLTEKGRKLEEPAKSIMPEYNSMIYNGISNKEKQELLGILQKMYNNIEN--- ->tr|A0A174AVI2|A0A174AVI2_SARVE Salmolysin OS=Sarcina ventriculi GN=slyA PE=4 SV=1 -----------RIKLSKWADILSNNFQAYVNL--KLKPYDLKFAEFICLLNLYENDGSHQDFIIKRKYTDKSAITRTLQSLEKKGFVRREKSEEDKRINCVYLTEKALDYKEELDKIIDEWEEFLNDCIPRDEYNKIATALEDITIKVLT--- ->tr|F8ED64|F8ED64_RUNSL Transcriptional regulator, MarR family OS=Runella slithyformis (strain ATCC 29530 / DSM 19594 / LMG 11500 / NCIMB 11436 / LSU 4 -----------EKNIGRYIGRLNYLGLKRMNELLTEAGANITADQFRLLTHLWKQDGIPQNQLALHLGRDRAGVTRMVDILENQHIITRIADTNDRRINLIYLTKTGKELETKAAECAQKYLNEMMEDFSEDEKIQFSSLLQRAVTSLKK--- ->tr|A0A0C2SYG4|A0A0C2SYG4_BACPU Uncharacterized protein OS=Bacillus pumilus GN=B4127_2035 PE=4 SV=1 -----------HDLIGYLVHRTDVKMTNYFTN--RLKPYGVTPEQWSIISILSREKGSTQKELAEGIDKNQTTVVRMIQSMERKGLVKKIYNEQDRRSHHLFLTEKGDEIKKAILPVVMDAHRTVTHQLSDEEIQQLKLLLNKLFHSDYP--- ->tr|A0A1M6WW48|A0A1M6WW48_9FIRM DNA-binding transcriptional regulator, MarR family OS=Anaerocolumna jejuensis DSM 15929 GN=SAMN02745136_03787 PE=4 SV=1 -----------TKLIGYKIIKGEVLIKRKILNAFIEKGYMITFEQWIVLNVLYAEPGIIQSEIAQRTYKDKTNVTRILDVLAKNGYIIREANDKDRRIACVYLTDAAKKMFADIIPYIEEINEHFCNGISEEELALFDDIFGRLCKNAE---- ->tr|A0A1V9JTI8|A0A1V9JTI8_VIBSP MarR family transcriptional regulator OS=Vibrio splendidus GN=BK411_02235 PE=4 SV=1 -----------QKSFGWMINVIANKSTKDFDT--ELKEHGLSIALWPTMMCLWEEEGVTQRDIAAKSKVENSTTTRTLDKLEKLELVERRADPNSRRSFRIYLTEKGKALEEQLVPIPVRLNKELMNELDAEEQQQMLKLLQKVVAAI----- ->tr|M1WNE2|M1WNE2_PSEP2 Putative Transcriptional regulator, marR family OS=Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN= -----------TETLGFQLYLSARLLKARFRRALVDAGCELTPEQHAVLRKLWECEGVHLNELAQSIFKDRHNTTRIVKNLEKKGLVYKLPHEKDARLTRCFLTEEGKQLIPGLVDIATSHLSEVFKDIDEEDRVVMQRVLGQLVMTLEN--- ->tr|A0A0M2H6V3|A0A0M2H6V3_9MICO DNA-binding transcriptional repressor MarR OS=Microbacterium trichothecenolyticum GN=RS82_04002 PE=4 SV=1 -----------------------------------LADRAARRCARThVLWLVFHEGPRTQAELATGLGVTPRNVTTLVDGLEATGFARREPHPHDRRAVLVTLTDRGEVAMRAMDAEHTRLGAQLIDGLDDATAQATLRGLNHVLDRLSRL-- ->tr|A0A1E3GA93|A0A1E3GA93_9GAMM MarR family transcriptional regulator OS=Piscirickettsia sp. Y2 GN=BGC07_07015 PE=4 SV=1 -----------------------------------S--qgLGIGPTERRALYAIYQNPGLTQVQLAEFLDIEPQGLTRILDHFVDLNWLRKEIAPKDRRARCLYLTSASNPIIEKIRAIGDEFRPQSLENISNNELENFINTIKKMKENLATI-- ->tr|A0A1B6ZE56|A0A1B6ZE56_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium EhC05 GN=A8B75_06855 PE=4 SV=1 -----------------------------------MQQLGLTRAQWQVLVRVLIIGSPTQTELADSLDIGRASAGNLIRQLEEKGYIKRYDDEDDQRVRRVIASKRAIASSEKMTQIGSDVASRAFAGIAEDELAVAAQVLGSIRRNVANL-- ->tr|A0A1D2SSV6|A0A1D2SSV6_9RHIZ Transcriptional regulator OS=Mesorhizobium sp. SCN 65-20 GN=ABS58_07645 PE=4 SV=1 -----------------------------------MRAagHGWFSEGRAGLLGHIPRRGTRQAGLIDRTGVSKQAVQQLLDGLEAEGVIERASDPDDKRGKLVLYTPKGLAALDDGDRIKLDIETRYRDHLGEGTFEALMAALSGLAEPRAK--- ->tr|D7DRT4|D7DRT4_METV3 Transcriptional regulator, MarR family OS=Methanococcus voltae (strain ATCC BAA-1334 / A3) GN=Mvol_0184 PE=4 SV=1 -----------ERSENNSINHLLYSIKTELCKKCNqsFKELGVTGSQFNVLEVLWHKDGITQSEIQRYLGIKASSVSNLIDHLEKKELIERVFDENDSRVKLIYLTKKGLELKEQGYEKCSAQTEMILSGFSDAEELELKNYLKRLISNLG---- ->tr|A0A1J0GMA2|A0A1J0GMA2_9CLOT Uncharacterized protein OS=Clostridium estertheticum subsp. estertheticum GN=A7L45_02795 PE=4 SV=1 -----------MGNEEMWIGYWLTKSVRLLNKFHDnkLQKYDLTSSQVAVLQKLWGEDGKTQKQLQENLGLTPASVSGILDTLANKGFIVRKHDEIDSRVNRIYLTLEGAKLEKLCHGIINEIEKTISDGFTCDEIKIFIAWTKKMHKNIC---- ->tr|A0A1C6HVZ3|A0A1C6HVZ3_9FIRM Regulator of autolytic activity OS=uncultured Anaerotruncus sp. GN=mgrA PE=4 SV=1 -----------ELGDMPRISYPVSTLYRRMQRYLSrkLAEegLPVEAGQLPALLHTYWHPGITQDGIAAGVGIDKGTAARALARLEELSLICRVPDEVDKRVRRIHLTEQGLAIRQQVMDIYSQMYEILYQGLSQQEIAQAAALLGQLSENMH---- ->tr|A0A1C6LW86|A0A1C6LW86_9BURK DNA-binding transcriptional regulator, MarR family OS=Variovorax sp. HW608 GN=VAR608DRAFT_0496 PE=4 SV=1 ------------------------LRRSAFDRSMKPLGI--TRSQWWVLAYLSREDGMTQSRLAEELDLGKVAIGGLIDRLQKSGLVRRVADPADRRINRVFLEPSSKRMIARLRSVEAQLNEEILEGVTERELEVAAATLATIKHNLLKY-- ->tr|K4MQ58|K4MQ58_9EURY MarR family transcriptional regulator OS=Methanolobus psychrophilus R15 GN=Mpsy_1880 PE=4 SV=1 -----------------SIGRDAFLFSREIHTFIAreMEPYGIGSGQFPFLMRLLHHDGISQEVLIRDLNCDRATGTRAINKLEENGYVLRETDPQDKRAYRVCLTDKSRQLEPVIKQMSVLINDIVFDGFTGEEKILFVQMIKRAIGNLSR--- ->tr|A0A0M9DS05|A0A0M9DS05_9BACT Uncharacterized protein OS=bacterium 336/3 GN=AD998_06295 PE=4 SV=1 -----------------AVGLYFYLLDKLYQRLLSydLDFTGLE-RYFMVLWAIDESESLTQQNLADLLKIDKASVVRIADDLEKKGFIQRVMNPMDKRAYFLELSKKGNKYIKDIHEGIDNLNSEMFIGFTQKEKEIFVELLNKAYLNLSQ--- ->tr|V5WL35|V5WL35_9SPIO Transcriptional regulator, MarR family OS=Salinispira pacifica GN=L21SP2_3021 PE=4 SV=1 -----------------SFGLWISIINRSAQSYFYhkLEPFGLGTGQQAYLLALLPGEEIVQDQLAQRLQIDRANVTRALGSLIKSGYVQRRISPEDRRARLVSLTEKGTEVRREVEGIASQWIETLQKAVSADEWNQSEQTLRKIALSLHE--- ->tr|W0EQ88|W0EQ88_9FIRM Uncharacterized protein OS=Dehalobacter restrictus DSM 9455 GN=DEHRE_03660 PE=4 SV=1 -----------------SPGSRIAVLYRMDRDFFAkkLKEYCLGTSEMAVLLQLSYYRELSQDQISTNIVMDKTTLSKIVKKLLHKGHIYMVRDTQDNRVHLLGLTQKGQEMIPVLKDATAEWVSIISKGFEPEEITLFCNILDRMIVSVEA--- ->tr|G4HL21|G4HL21_9BACL Transcriptional regulator, MarR family OS=Paenibacillus lactis 154 GN=PaelaDRAFT_4682 PE=4 SV=1 -----------------AYGKEVTAINRHLQLLLSprLAALQLGFGQHMFLLMLSRKEGMNQKTLSEQLLLDKTTTAKAIRKLELEGYVRKEMDPADLRNHQLFLTDAGKAVVPKIEEALAEVMEIGIEGMSAEEYGEFMRLLKIVLNNFDK--- ->tr|A0A101J001|A0A101J001_9EURY Transcriptional regulator, MarR family OS=Methanomicrobiales archaeon 53_19 GN=XE11_0540 PE=4 SV=1 -----------------RVTKKIGYLYWSNRTLFTkLFPHPLGPGQAAFLIYLTEDTEVRQETLASMIGVDKAIGTRVIRKLNEAGYIRRRRDPENYRAYLISLTEEGNEMKDAILEVSNFIDESLLNGFTDEERDMMHNLLDRMIVNIGQ--- ->tr|D4H6X7|D4H6X7_DENA2 Transcriptional regulator, MarR family OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_1067 PE=4 SV=1 -----------------SAGKQISHISRSISRYLDakVNSLNLSYSVIPFLTYLYEHDGVHQDELAANLHYDKSSATRAITALVKQGYVTRQIDKRNKRRNIINVTIKGYTIKDELILILRRTTQKLFNDFTDEEINLYFKLSDKIDKNLDN--- ->tr|N1Z975|N1Z975_9CLOT Uncharacterized protein OS=Clostridium sp. ASF356 GN=C820_02838 PE=4 SV=1 -----------------SIGRIVMLLSRSICNDVRyvIEPFGLTVGEESYFIALAHEDGLTQDELSSRVNVDKSATARAVKSLEAKGYIEREIDPFDRRNKKLYFTEKAKKVYISLSEALGKYNQQLTNEWTDEQYNLIYESLEMLQLKLEI--- ->tr|I2EVT9|I2EVT9_EMTOG Transcriptional regulator, MarR family OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=Emtol_2656 PE=4 SV=1 -----------------VFGSTIRALHKATALEFDKSGLEISPEQYHLLKIIASKEDSIQAELAEIMQLDKSGIMRHIDQMEARGFVQRVNDAQDRRKKYIVLTESGIQKLDNCKIALDKMANTILKGVSDAELLIFKQVLTKLKENAGG--- ->tr|A0A1F2PCW9|A0A1F2PCW9_9FIRM Transcriptional regulator SlyA OS=Acetobacterium wieringae GN=ACWI_32510 PE=4 SV=1 -----------------DFGKMIRTITANTNNYIGgmIEKFGIRQGQFEYFLLIYGSPGINQNELARLKSVGKASVTKALKILEDDGFIRRVSDDVDKRNTRCYITGKGELIVNDLLKIRAEAEKVLFDGFTEAGKAALYEHLFRLYQNSEQ--- ->tr|A0A1F9ZTU3|A0A1F9ZTU3_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_04850 PE=4 SV=1 -----------------NIGRSMSILHRQAQVFHThsLKSFGISAGEYPFLLYLYTHDGCTQDDLVNALTIDKAATARAIASLEEKGYVSRGKIDADKRCNHIKLSDKAKENEVEIRRRVYAWSEFLSEDIDPETLKIVEDTLDKMVEKVEK--- ->tr|A0A1M5TAR4|A0A1M5TAR4_9FIRM Transcriptional regulator, MarR family OS=Sporobacter termitidis DSM 10068 GN=SAMN02745823_00012 PE=4 SV=1 -----------------SLSLWFSILYRYRKNYLMkkLERYGVIGGYPYMILAIHKNAGTNQEQISNILKTDKAAVTRAVKKLEKEDYILREPDLSDKRAYRVTLTPKAEAVVPEIRKALQEWEQIAVAGIPEDMLPVLRQYVKQMSDNAVA--- ->tr|A0A1V4TJ57|A0A1V4TJ57_9EURY Transcriptional regulator SlyA OS=Methanobacterium sp. PtaB.Bin024 GN=A4E25_01137 PE=4 SV=1 -----------------PFKGIISIILRNHFVFMNkeLKHLNLTEGQVPCLVALSKEEQLTQDDLARMFHIDKGTIARSIQKLEDKKMVRRVQDPVNRRRYILYLTEKGENIIPEILDAEKKWEDTIFKDFSEEERSFLVDGVESLAKNSLE--- ->tr|A0A1V5SJG0|A0A1V5SJG0_9EURY DNA-binding transcriptional repressor MarR OS=Euryarchaeota archaeon ADurb.Bin294 GN=BWY45_02528 PE=4 SV=1 -----------------PPGPLLSIINRARVIFLNerLKPFKLSAGQYPVFMCLLKHPDITQDTMARYFHLDKGTIARTVKKMEDAEYISRRVDPDNRRAFRLSLTRKGYQIAPEIMAIDQEWEQAVSCQLTKEEKEHLQVLLRQVASSSIQ--- ->tr|J0B2J4|J0B2J4_ALCFA MarR family transcriptional regulator OS=Alcaligenes faecalis subsp. faecalis NCIB 8687 GN=QWA_06775 PE=4 SV=1 ----------------------------------TLGRYGVSEATILPIRYLAQLgEPIRQGQLARMMRLEGPTLVRLIDQLESTGLLERVPDEQDKRARLLCLTDKGRDFHAHLLELLRQSRAPLFAGIPEQDIKAALRCFDMLASNLGLKA- ->tr|U3A0J4|U3A0J4_9SPHN Putative MarR family transcriptional regulator OS=Novosphingobium tardaugens NBRC 16725 GN=NT2_02_03650 PE=4 SV=1 -----------------------------------MREVGVTGAQARLLMILAADEGRQQTHYASVLEVEPITLCRMVDRMVEADLIERSPDPNDRRARLLSRSDKARALEPVLQEKIDQLVDDIQSPFTSDELQILHRLLSRMGEQLVSPS- ->tr|A0A1G2W7L3|A0A1G2W7L3_9CAUL Uncharacterized protein OS=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 GN=A2790_08180 PE=4 SV=1 ----------------------------------RVRSLGLTRPQWRVLVYVMQNEGLSQSMLARAMDIERAPVGQLLRALEALRLVRRVRSSADQREWLIYGGEGSRDMMPQLVEAASWLRGVYFQGLTRSEEQMLHRILERMRSNLSYEL- ->tr|A0A078MGE8|A0A078MGE8_9PSED MarR family transcriptional regulator OS=Pseudomonas saudimassiliensis GN=BN1049_02062 PE=4 SV=1 ----------------------------------KMAAAGFADISWSPLIHLAESgDGVSQKALAALVGIDGSSLVRLLDTLESRGHIQRCPCPDDRRVKLVMLTADGQQMVHTIRDHLERIEREMLQDLDDEQLLAMLGGFDRIKDRLALMA- ->tr|A0A0F2PJW3|A0A0F2PJW3_9FIRM MarR family transcriptional regulator OS=Peptococcaceae bacterium BRH_c8a GN=VR67_02820 PE=4 SV=1 --------------ICYKLSKVMRKVQRYYEASL--VHFEITPVQFYVLSALLSSDGMKFKDLAKSVGIDGSTLTGILDRMARGGFVERRDDPEDRRSLLIYLTEKSKEMGPDMMKLAEKLDRDIKEQFPGAEFATFMKVLDQLSETT----- ->tr|A3ZXC9|A3ZXC9_9PLAN Regulatory protein, MarR OS=Blastopirellula marina DSM 3645 GN=DSM3645_30051 PE=4 SV=1 --------------LGVAM----RRVARLYTEEL--APFQLTPPQLYLLTCLEQNAGCKPREIARSICVDASSITSLLDRSEQAGLIQRQADPADRRSLQIFLTDLGRRRLATVAETVEALNQRIRDELlapfNDEQVDLFLTMLRGIGKDD----- ->tr|A0A0C1RYU1|A0A0C1RYU1_9DELT MarR family transcriptional regulator OS=Smithella sp. SC_K08D17 GN=DS62_08300 PE=4 SV=1 --------------VCFQLTSASQKIRRRYRDGI--AKYQLTHGQFFMLCAILEEEGLLPSHLADKTELDRPTATGLLDRLERDGWIERHTEPSDRRMYRISPSAKAIKHKGDLLNLFEQTNSHFIN--rfTPDEWEQFQEYLNRLElP------- ->tr|A0A161TB85|A0A161TB85_9BACI MarR family transcriptional regulator OS=Bacillus marisflavi GN=AV649_16890 PE=4 SV=1 --------------INFLLSASQNKVFKYFSKLL--EDCGVTPAQYGVLNCLWKEGQLSPKQIGEMVYLEASTVSGILDKMQKLELIERSIDPSNRRNILVRATHKSQAIRDEVEAVTSKMNNKILQNLSDRDTEVLKRALEVIIkSDL----- ->tr|A0A1G2VF90|A0A1G2VF90_9BACT Uncharacterized protein OS=Parcubacteria group bacterium RIFCSPHIGHO2_01_FULL_47_10b GN=A2666_01975 PE=4 SV=1 --------------IVIKFGRvq--KKLSAFYDRAF--DPFHLTLAQFLLLVVLFERNGRTVKEFGATLGLKGGAITPLLDQLERKGYIERRSDQFDRRAVQIMLTEQGRLSEQALRDLFEETNDKISRLLqakfRKEDVELLAQMVGYVDFSL----- ->tr|A0A1M6S042|A0A1M6S042_9DELT DNA-binding transcriptional regulator, MarR family OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_03356 PE=4 SV=1 --------------IMFQMAKAYQRVHAEFKSGA--AELGLTPIQCLVLQAVFEEPGLSSGEIGQRLHIDSATLSGILERLIERGWVVKNTSAKDRRVLEIHPTEQAMEQKTALDGMVESLNEKVLASFRVEEKMLLRRMLEDLAQ------- ->tr|A0A1Q9MRT0|A0A1Q9MRT0_9ARCH MarR family transcriptional regulator OS=Candidatus Lokiarchaeota archaeon CR_4 GN=RBG13Loki_3854 PE=4 SV=1 --------------TFDLLKKVRKRVSDLHRSLI--QKYGLSLSQYCILKQLWDVDEKAFKDLAECCHISRSTATGVVDTLEEKALVSRKTNPEDRRSIFVKLTDKGKSIRQVTPSQDAIVP----K--hkmQGEEIRTLNNLLAKLFkSLE----- ->tr|A0A0Q1BGA5|A0A0Q1BGA5_9FIRM Transcriptional regulator OS=Lachnospiraceae bacterium TF01-11 GN=APZ18_07035 PE=4 SV=1 ---------------------------------TSVKDTGLTSGQPKVLDYLKNHDGAVQKDIAINCHIEPASLTTILNGMENKGYITRNICTQNRKYLNVHLTKLGWKYVERLKKEFAKIENLALKTFTDTEKEQLIFLLEKLYDNLSEI-- ->tr|G7WEX4|G7WEX4_DESOD Transcriptional regulator OS=Desulfosporosinus orientis (strain ATCC 19365 / DSM 765 / NCIMB 8382 / VKM B-1628) GN=Desor_1660 P ---------------------------------ARVRECGMEKGQPRILDYVYVNDGCIQREIRDEFSLDASSISNLLAILEKDGTLRRKRNPLSSREVNVYITDKGREIQKRLEVVYDELEQITFQGFSPEEKEQCIHYLFRLTKNMMSY-- ->tr|D8IC31|D8IC31_BRAP9 Putative transcriptional regulator OS=Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000) GN=BP951000_0705 PE=4 SV=1 --------------------------YQYIGKQI--INFDITPEQLIVLKELAKEEGISQKELSIRLDKDQNTVKAMIDKLEVKSFIKRKENKLDKRAFSLYLTEKAKKELPIIENYENQVLDTIVKELNLNDAEIIKNTLKKIRSNISE--- ->tr|A0A1V5B2U9|A0A1V5B2U9_9EURY Transcriptional repressor MprA OS=Methanosaeta sp. PtaU1.Bin060 GN=A4E48_00961 PE=4 SV=1 ----------------------------MVQQII--KEFKATGQE-SALYAVVRNSGISQTEIARISIKDKANVTHIIDFLEEKGYIKRVSDHKDRRVNVIVPISGGEEVLERLIGVAQASNEAFVQDLTASERQSLKDSLRKISASLED--- ->tr|K5DAA4|K5DAA4_RHOBT MarR family transcriptional regulator OS=Rhodopirellula baltica SH28 GN=RBSH_04807 PE=4 SV=1 ------------------IGRVAYLMRTRMAAVLKQADWPFTPEETQTLVTLADVGePLSMSDLASRMVRDPTTVKRQLDRLVEHKFIQRSVSPKDARIVMVGLTARGEQQLQTVLPLLDELRKCALQGITKTQVTEIQKVLQKMQSNLA---- ->tr|K0NC11|K0NC11_DESTT Transcriptional regulator, MarR family OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=TOL2_C01210 PE=4 SV=1 ---------------------------------EKIKPLDIQPGHLPFIATLLDNEtPMIQDDIGSHVFIDKSVAARGIDSLEKKGFLNRSINPENRRQKLVELTNMSRNIKQKLFDSLNKASEELLSALSPEEQDRLMDLLDRMLHGAL---- ->tr|A0A0U5Q0J3|A0A0U5Q0J3_9RHOB DNA-binding transcriptional regulator, MarR family OS=Rhodobacteraceae bacterium HL-91 GN=Ga0058931_2886 PE=4 SV=1 ----------------------------------ALRPYGLSFAQFCMIDLIDRGGPHYPSSLARKLDIETSTMASTLKRAEGAGFIIRSPDPNDARGVVVTLTEHSREILPEARAAVLGIEEKCTGDLSGDERK-GGIEFLQRIGNSLGM-- ->tr|A0A1M3KU58|A0A1M3KU58_9RHIZ Uncharacterized protein OS=Devosia sp. 66-22 GN=BGO81_08330 PE=4 SV=1 ----------------------------------GLVPLGIAPPMFPLLVELWFGdTPVSRASLAATQEMEVADIDALVVAMAEAGLIERFAA---DPAAVLVLTAKGEAAKGPAVAAARRANAAAAAVLDEAEMAQLLGLMNRVIDALQGA-- ->tr|A0A1S1XDN6|A0A1S1XDN6_9NEIS Uncharacterized protein OS=Chromobacterium amazonense GN=BI343_09065 PE=4 SV=1 ----------------------------------RLQGTGITRSQRQILLMLHQSGDCTQKNLLGQLDMDPGQLARTLEGLEKDGYIRRRPWAANRRCMFVEMTEHCRDKLMpGLLAAVDSVDQQLFQGFSPEEQQKM-QTMLQRMQTNLSQ-- ->tr|A0A1L4A076|A0A1L4A076_9SPHN Uncharacterized protein OS=Sphingomonas sp. JJ-A5 GN=BSL82_17650 PE=4 SV=1 -----------------------------------IRDSGLRLSHWLTLKYIADGRICFIGDVYRELGITDGASTRLIDHLEQKGLVRRNRSRKDRRLVAVALQPEGERMVRQLRLRIERRWQRQLGPFCEADRIHITTALIHLIDAFRS--- ->tr|Q0G3J3|Q0G3J3_9RHIZ Transcriptional regulator, MarR family protein OS=Fulvimarina pelagi HTCC2506 GN=FP2506_15434 PE=4 SV=1 -------------QIALGLFDAARLLREAFEHAH--RDMKITWPQIRIMGRLYVQEGIAQSEIGAQLEMDPMTISRQIDRLVDLGFVERRTEQRDRRLRKLYLTRHSRILREDIEKRTQSVLNTALHGFDAERQASFLEMLKTFADNLCEP-- ->tr|B1KGY5|B1KGY5_SHEWM Transcriptional regulator, MarR family OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_4041 PE=4 SV=1 -------------ELAKLLVQNERLLDKKLESALQQRKKTLGNVQWRILTNLIEASeGLSMKDLSLLTHTNDSTLTKVVDKLVNDSLVYRRPHPKDRRKILIISSSKGKALHAKLESDVNQCYEKMFEPLSAQQMKSLQNILQTLNNEGSLT-- ->tr|A0A1C4XKM2|A0A1C4XKM2_9ACTN DNA-binding transcriptional regulator, MarR family OS=Micromonospora mirobrigensis GN=GA0070564_103165 PE=4 SV=1 ------------------MDDAaATLLAVWEAARER-TTSRLSSAQLRAVMVVEQHDGINLRRLATRLDMLLSSASRLCDRLVAAGMLEREPSRTDRREISLHLTPEARRLLAELRTDRRRRLAGVLAAMSPAGRQALLVGMREFDEVARER-- ->tr|A0A1L5M1J7|A0A1L5M1J7_9BRAD MarR family transcriptional regulator OS=Bradyrhizobium diazoefficiens GN=BD122_04640 PE=4 SV=1 -------------NFLFTLAELYRLLRVYADKEA--SRFGITRAQWAVLAKVERSEGMKQSELAELLEVQPITLTRLIDKLCDNDWIERRSDASDRRVKRLYLRKAGRQLLGKMSGLRSEITANALDGINPADAHRLLTQLEAIKENVRTA-- ->tr|A0A1V9KCX1|A0A1V9KCX1_9ACTN MarR family transcriptional regulator OS=Streptomyces sp. M41(2017) GN=B0675_10190 PE=4 SV=1 -------------QDLFsrsalAVFRLNGQYLSVAEDLA--RPAGITAAWWQVLGAVLG-EPLPVSGIARVMGITRQSVQRVADLLVDKGLAAYRPNPAHRRAKLLAPTEQGRAAVATIGPGHAAYADRIAEALGPEALAETVRVLERLSVVLDGL-- ->tr|R5MHS4|R5MHS4_9MOLU Transcriptional regulator MarR family OS=Mycoplasma sp. CAG:956 GN=BN817_01143 PE=4 SV=1 ---------------------HIINTDKLIGRYILdkfdkKARHRISPMQVMIMNYLLKNQNKkvFQQDICDTFNLRRSTVSGILTTMEKNDIIRRKVDTEDPRKNEVKLTKIFINNTKRVSNELVKMESILEQNFTQEEKKELIRLLQKLEGNLIKE-- ->tr|R7HDZ5|R7HDZ5_9MOLU MarR family transcriptional regulator OS=Mycoplasma sp. CAG:472 GN=BN672_00464 PE=4 SV=1 ---------------------DIKIFHQLVINSIGvkdmPKYPSVTTTQIQIMEYIISRPKKcaLQKEFEKVLGLSRATVSSVLITMEKNGLIVRITDNTDTRTKKIVLSSNAQRVFNSSKEKIKKIEDICLKDITEKDLNTFINVLSKMTENLKEE-- ->tr|A0A0N1MK69|A0A0N1MK69_9FLAO MarR family transcriptional regulator OS=Chryseobacterium sp. ERMR1:04 GN=AMQ68_06545 PE=4 SV=1 ------NISEIALELGLAMGEMKSRLRQKIQAKINEYDPDLSFELIEILGLLSRNNGINQQEISSKVSKDKSSITYLINSLVKRELVERVENTTDRRNKQIFLTVKGNEIVETVYPWALELYKKAADDLDEDDINRALLLVKKMTANL----- ->tr|R5USX4|R5USX4_9BACT Uncharacterized protein OS=Odoribacter laneus CAG:561 GN=BN709_00763 PE=4 SV=1 ------DIRELVVYLSKA----ERGYTKTLNRAFQQAGYDLSREQFELLQVLWEGDHINQQAISRKLQKDKYNVTKLLNTLTKRGFVQRTMSQEDRRNNFVILTEKGMQVQKALLQIEEQVHTDLTFTLTPSEIKSCMWVMRKLTDMM----- ->tr|A0A1M7AVM5|A0A1M7AVM5_9BACT Transcriptional regulator, MarR family OS=Chitinophaga jiangningensis GN=SAMN05444266_103428 PE=4 SV=1 ------EIADiLRSAVSRNITRAHTAYRLRLLAVFMEKGVDLTPDMYFILRHLWGeQDGCRQQELADKTDKDKASLTKLVDNLEKRGLVRRSMDGEDRRSKRVWLTPVGKDLKEIVYPLALQVVATAENGVDQEDIQRVKQTLDALVKNL----- ->tr|A0A0F7M0W9|A0A0F7M0W9_9GAMM Transcriptional regulator, MarR family OS=Spongiibacter sp. IMCC21906 GN=IMCC21906_00256 PE=4 SV=1 ---------------------------------IQEHQISLPINHIRVLKGICRLPDSTAQSIAHKMNQDKAQVTRVLNALLQSGFIEKSEKPSDRRSQLLIPTIAGQKMLSKIDAIEEQAAAYMTRNLNTQDLEAFVRISNAMLEKPSKA-- ->tr|J8T753|J8T753_9ENTR Multiple antibiotic resistance protein OS=Pectobacterium wasabiae CFBP 3304 GN=Y17_2786 PE=4 SV=1 ---------------------------------MKAHDINLDVVHIRLCKIIAAAGRITPQLLAKTVGRDKAQITRMVAELVKRDYVRKIDNPDDGRSVWLSLSDKGIAFTQVFLHQEKHIEAQMLQALSSDEQAMFSALLEKIAASDSAH-- ->tr|A0A0C1PUP1|A0A0C1PUP1_9GAMM MarR family transcriptional regulator OS=Pseudoalteromonas elyakovii GN=QT15_01195 PE=4 SV=1 ---------------------------------VREQGIDMVPMEIQSLHLINRTENCTAALMSELMDRDKSQLARLIKEMSKKGLIEKTKNPNDTRSHFLGLTEDGKAILKRMLVIEAGLIQKMCTDLSHEQVEVFNNIAVIMTANLARE-- ->tr|E8V5D8|E8V5D8_TERSS Transcriptional regulator, MarR family OS=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) GN=AciPR4_4151 PE=4 -----------------------------------LRPYDIGSTQWYVLYQLANEGPTMQRDLVRMLQIERATLSGVVATLVRKGLVDQAPDAVDQRQRVLRITASGKKLWKTLPDPITLILATAFDGMNPAELAVARRVLQTATQRLNAH-- ->tr|T4VQH4|T4VQH4_CLOBI MarR family protein OS=Paraclostridium bifermentans ATCC 638 GN=C672_2304 PE=4 SV=1 -----------------------------------LKDRNLGQGQLLTLMTLfklKNYDEITQEDLAKVMGINKANTSRNLAKLKESGFIVINQSKDDQRKKNIELTNKAFEEFLYLEKIMREIHNEMISGLDSDSLDSTLSTLIKMKENLLNK-- ->tr|A0A223B2C5|A0A223B2C5_9FIRM Uncharacterized protein OS=Eubacterium minutum ATCC 700079 GN=AXF21_04975 PE=4 SV=1 -----------------------------------LQIIDFSWREMVVLMVLEKKPGATQNFVGKFLQTDKSNVTHIIQGLETKTFLIRKTCEKDRRYKGLYLTSVSRKLLPWLHEQLRLWQEQCYQGLSQEEITIYQNLNQKIIDNLFAF-- ->tr|A0A085WPF3|A0A085WPF3_9DELT Transcriptional regulator, MarR family protein OS=Hyalangium minutum GN=DB31_6541 PE=4 SV=1 -------------RLRHLLIdVGRQGIFSSPLA--APAEGDMEPLHFESLWWLRAEGFLTINTLAErLGGVAMPRMSRMIDRLEEAGWVQRVKIvREDRRHVSVRLTDSGRAQAEQVDALVQARMARLLLPLAGEDRSALMDLLERWVEA------ ->tr|W0VAN4|W0VAN4_9BURK MarR family protein OS=Janthinobacterium agaricidamnosum NBRC 102515 = DSM 9628 GN=GJA_4050 PE=4 SV=1 -------------RLARMTSHIQKGLKDSTNA--ALKKHDLTDVSYMVLAVLYGTedASSNARTLGIACNEKPANLTRVCNELEQRGLIHRGSRPGDRRSVMITLTDAGRALICLALPDVYRRNVHVYDGFNAEELQQLEKMFARQLHN------ ->tr|A0A1A9DDM6|A0A1A9DDM6_9ACTN DNA-binding transcriptional regulator, MarR family OS=Streptomyces sp. OspMP-M45 GN=YUMDRAFT_06550 PE=4 SV=1 -------------HVPYLLAVASTVAARRVDE--RLAAYGLTVRQYGLLAQLSLEPELTMAELARQLGIARQSVHQLVNELVGAGHVRRRPGADDR-SRRLEITDTAHYLLTRIDGPLERVEAELLGELAPDEAETLRSLLQRVLAH------ ->tr|A0A1E7Z733|A0A1E7Z733_9ALTE Uncharacterized protein OS=Alteromonas confluentis GN=BFC18_18105 PE=4 SV=1 -------------DFGKHIAMVRNLMMSRLDE--LLKEFDLTGSQYAVIKHIAEGRADTLAKLCELLQYDKGAMSRILSRMEDKSLIIRKPCPDDGRAFRLKLTPRGKELFPQTTPKVNALFEQALAEFSAKEKEAFFSMLERCRSN------ ->tr|A0A1Q3SVD8|A0A1Q3SVD8_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 39-13 GN=BGO43_09510 PE=4 SV=1 -------------SIGYLIRRASKLVISQVEA--LFAEQDISFTQYVVLVLLRDNLASTASDICQQLGYDTGALTRVIEQLRRRELIERKRNIKDKRIISLSLSPLGRETIENFCPLVFNHYNQRLEDFSFKEIDTLLTLLTKFIAS------ ->tr|A0A149PR57|A0A149PR57_9BURK Uncharacterized protein OS=Paraburkholderia monticola GN=CI15_15230 PE=4 SV=1 -------------KLMSVLGQARQLIAGELRA--GLADAGLNLQERAVLLTLAHGSVRTPAALSKLAGVHPARMTRVLDKLESNGLIERARNGRDRRLVDVSLTREGQAVAARNARVALGAWSERLSHFSKSDFDTLSALLSRLIGH------ ->tr|A0A1L6HW43|A0A1L6HW43_9BURK Uncharacterized protein OS=Paraburkholderia sp. SOS3 GN=BTO02_09940 PE=4 SV=1 ----------------MALRRTGDLVIHEIDA--GLSDFAVNFLQLSMLVAIASGRAHSPAGIAQKLDVDRAVVTRALDKLEANHFVQRRRSVDDRRNVLVSLTEPGAISFNKLCNVASAILRARLGKVPSGECEHLQCLLALVRGV------ ->tr|A0A1Q6RTJ7|A0A1Q6RTJ7_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:176_59_8 GN=BHW34_01820 PE=4 SV=1 -------------HFGPLFGYCHHQVQKLMNR--LLRQYDVSPMQCRTLTFLHDAeGEVNQKALEKHLMVKPSTVNGIVDRLEEKEMLRRTTSKTDGRCRILELTDQGMQFYDNFTAVVRQVDTRLERDFTDEEKKLLLSLLMRVARN------ ->tr|A0A1Y0H0N9|A0A1Y0H0N9_9BACT Uncharacterized protein OS=Armatimonadetes bacterium Uphvl-Ar1 GN=CCB80_11060 PE=4 SV=1 --------------------------------------AGIRWTTFQLLAAViG-aGDQASQAEIARRLAVAPATLSEAVQTHVRQGLLIQAPAPTDRRKKILQLTPEAKRKMSKVAVHVQTLEQLLTASISPKLIAETETALEKM--------- ->tr|A0A196PK79|A0A196PK79_9RHOB Uncharacterized protein OS=Sulfitobacter pontiacus GN=A8B81_12580 PE=4 SV=1 ----------------------------------Q--HVNLTPIQYTILVIIDMEPGVEQTSIASRAGLDASTVADVVKRLVKHGMIKREVGIRDKRSRVAFITSSGKAAITDAAPLIEDAIQNMLSPLASDEQQNFLSMIDRILTHNT---- ->tr|U2NPZ7|U2NPZ7_9CLOT Transcriptional regulator OS=Clostridium intestinale URNW GN=CINTURNW_2306 PE=4 SV=1 ----------------------------------NLDKYDLTTSQWAVIKLLYNKKELTQAQIADELKSDRATAGNVILNLYEKKYVDKRIGEKDRRTYIICLTEKAMKAVNEIELIAEEVTRKALYGLDDKHIKIMYEGLNKVINNLSEG-- ->tr|R7HRQ0|R7HRQ0_9CLOT Transcriptional regulator MarR family OS=Clostridium sp. CAG:768 GN=BN776_00091 PE=4 SV=1 -------------------ARVAEL---MARNCYKIYQdtdkPILDLDEFKIISHIMDDPDLSQSDIAKLVYKGKAHVGKILNELEKKHYIKRDLTTRNNiIIKHTIITEQGKEIYFYTDERFKEINQNIKKMFSEEELNTLKALLDKLKIAMLN--- ->tr|R7LRX3|R7LRX3_9FUSO Transcriptional regulator OS=Fusobacterium sp. CAG:815 GN=BN791_00428 PE=4 SV=1 -------------------AKYCKY---LGMQIFQKLDLPISLDEFVILDILIDNEEICQRDLAKLILKDRPCTGRLLNSLEKKGFIKRFVDTKNNrLVKKMKLTSAGIETTEKVTIIIKNYMDKLPKVLSDDDKLELINSIKKFRESLEK--- ->tr|A0A1Q6TTX0|A0A1Q6TTX0_9GAMM Uncharacterized protein OS=Acinetobacter sp. CAG:196_36_41 GN=BHW62_04180 PE=4 SV=1 -------------------SRVLHE---ATRCFFELQKFPISQEEFIILDCLYINPNIIQMEIAKLILKGRAHTGKFLKSLEEKKLITRTPVKQGSkIVMQIKITDKGLKTYRKIANALDEHIKDASAGLK-IRINDVISALQTIREDAVT--- ->tr|A0A094IK15|A0A094IK15_9BACT HTH-type transcriptional regulator MgrA OS=Candidatus Izimaplasma sp. HR2 GN=mgrA PE=4 SV=1 ------------------------------------ERLNITYSQLMVLRVANQEPGITAKEILMQMDTDKATLSGVLARLERDNYIYRVKNEKDKRIQNIFVSEGSERLCTEVSVIERACISDLIDGISDTEAENFLSILDRFIANQ----- ->tr|A0A0C5BVF2|A0A0C5BVF2_9ARCH Putative Transcriptional regulator, MarR family protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1024 PE=4 SV=1 -----------TDSIGLMMKRSAKSWERATDI--EMtERFGLTGGKWKTITGLSIKEGITQKQLADMMFVEAPTLVPIIDKLEKEGYIVRKTDPNDRRNNLVFLTDKAKKTTDSIIDCISEMRDVGLEKISKKDLEITKKTLMQINANADAF-- ->tr|Q0W653|Q0W653_METAR Putative transcription regulator (MarR family) OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=RCIX763 PE -----------SEAHALLPGLVKVMWAMRVDR--PSawspAFEGLTPLDLH-ILAFIEaRPDVILKELRNYLDVPNSTLTGLIDRLEKKGLIERVISGRDRRSFGLKLTAKGADLRKEQQQVRLASASKMLGALDsDEERRAFVGMLNKIGDRLILG-- ->tr|A0A0X1SZX1|A0A0X1SZX1_PSEAA MarR family transcriptional regulator OS=Pseudomonas agarici GN=AWM79_08665 PE=4 SV=1 -----------EHRFGMQLAHMSRGWRAELDR--RLAGLSLSQARWLVLLHLARfAQAPTQRELAQSVGVEGPTLARLLDSLETQGLVQRQAVLEDRRAKKIVLCPSACPLIEQIETIATALRHELFVGIDEEELRICMRVHSRILANLEKS-- ->tr|A0A0J1HF88|A0A0J1HF88_9GAMM MarR family transcriptional regulator OS=Photobacterium ganghwense GN=ABT57_06760 PE=4 SV=1 ----------QDLSLAEQLARVSRLWRMVADR--ELAPLGLTHPRWTALWKLQRLGdNISQKTLAEALEIELASLMRTLKQLEEQGLIVRHCCDHDKRARIVSLTEEGRTLIAQMETRILQVRRNLLTDISEQELMRLSEVLETIANNALT--- ->tr|A0A0M8U120|A0A0M8U120_9ACTN Uncharacterized protein OS=Streptomyces sp. XY431 GN=ADK60_38225 PE=4 SV=1 ----------MRTSVAPKLHLTAKSCRAFFEE--RLAEAGATFAAWTVLAALKLEGPMIQRALAQYLSIEGPTLSRHLESMERRGLVVRKRTDVDRRAATVEIAPDGEEMYNRISSVAISSQQDMLKGLSDREVAQLATLLDRILENVGP--- ->tr|A0A1G0LZ37|A0A1G0LZ37_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium GWC2_71_10 GN=A2085_04985 PE=4 SV=1 ----------------------------------FARDHGLSPPEVRCLAAFGDEPELTAKQLTRRLGFCHSRLSHVLDSLEGHGLISRRINETDRRIIDVSLSGNGLDLVARLEAAVFGCYEPPLRSTPRRATETAVAVLARAFAA------ ->tr|A0A1Y5GHD3|A0A1Y5GHD3_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 45_16_T64 GN=A9Q99_25445 PE=4 SV=1 ------------------------------AKRIKRAGINLTPEESVLMNQLWDRDNQTLGELGQWSVKDSSTLTRQVDGLVKKGYVERVHGTEDRRNVFVRLSDSGKKLKIAFRKTGVANLDQDMIHHSEAEVNKALTLIMAVRERALK--- ->tr|A0A0A6V9I9|A0A0A6V9I9_9BACI MarR family transcriptional regulator OS=Bacillus ginsengihumi GN=NG54_13315 PE=4 SV=1 ---------------------------------LINGDKKITRLQWTLLCHVGKSEHCTMGNLADHFNVNMSTVSQMIDRLEKWGYVERGTSAHDARVKIVSLTEKGETIIKEVRAAYLQQLASGLNKFSEDEQDTFIGYLQQLAENLRDV-- ->tr|A0A1F9PIM9|A0A1F9PIM9_9DELT MarR family transcriptional regulator OS=Desulfuromonadales bacterium GWC2_61_20 GN=A2005_08595 PE=4 SV=1 ---------------------------------LVHEGIDLTSNQYKTLLAVAGRGECSLGDLARTLEVAMSSASQMVDRLVSSGLLLRAPAIDNRRQVVIRLSPQGVTLIAELQQATLQGYHKVLARLPEQEQEDLVTAFETIATILNKL-- ->tr|D8WWQ2|D8WWQ2_9FIRM Putative MarR family transcriptional regulator (Fragment) OS=Clostridia bacterium enrichment culture clone BF PE=4 SV=1 ------------AEVTQHLLNVYRQLYNRYNEFA--AKFELTATQLASLERLWLSEGITVGELGQIIGIERSSVTGLVNRMVAKKLIVKNQDQTDKRLMRLYLTRNAKERLATKKSEqysfSRTIGDYLESQLVSDEITQLNLLLQKVGTALEK--- ->tr|I2IH00|I2IH00_9BURK Transcriptional regulator OS=Burkholderia sp. Ch1-1 GN=BCh11DRAFT_05466 PE=4 SV=1 ------------HSLLHVMSRTNVAMWQLVTHKT-HAMGGITGMQASVLLLLMYRHSATSMDLAREYKLHSSAITRLVDRLVRLELVERIPCENDRRATYLRATSRGRRISEQLPAIFTDAFETLFDGIDERDVDTLRRCLKHILLNARA--- ->tr|A0A0P7W2E9|A0A0P7W2E9_9RHOB MarR family transcriptional regulator OS=Oceanicaulis sp. HLUCCA04 GN=HLUCCA04_11470 PE=4 SV=1 ------------RRLYLLLEITARRLHRTADARL-RREAGVSAAQSAVLFLLMRRGERRMGAISETLALGAPAVTGLITRMEAAGLVSRSTDSGDRRGAIVTLTEAGRELAVKADQVLRDINLELAERLGDEDTDRLHDLLGRLNSDEAG--- ->tr|A0A1E4LUR7|A0A1E4LUR7_9BURK Uncharacterized protein OS=Comamonadaceae bacterium SCN 68-20 GN=ABT02_07530 PE=4 SV=1 ------------PRLVYLLGSAQRRLQQWIAVQQEraalSGARPPTPAQAGVLFVLARSDGVAMGQLAEALDLAPSAASGLAQRMEALGWVARRPSPHDARTLQLWLLPAGQAQLPGLRTATQCINQRLTAGFTDAELHTVARWLEHVQTLGAP--- ->tr|A0A1N6DCJ6|A0A1N6DCJ6_9SPHN DNA-binding transcriptional regulator, MarR family OS=Sphingorhabdus marina DSM 22363 GN=SAMN02745824_1809 PE=4 SV=1 ------------------MQKAHSSLFRAADRFL-GEEVGLSTSQHAVLLILMQHDGAPISAIAGELKMGKSSLTGLIDRMEKKGLVSRRQSADDARSFEIHIRDHGRHLVRSTLPGTKRINRSILEPFSAQEQEVIARFLNHVASNADE--- ->tr|A0A1X7AN67|A0A1X7AN67_9GAMM DNA-binding transcriptional repressor MarR OS=Endozoicomonas sp. S-B4-1U GN=EHSB41UT_03344 PE=4 SV=1 ------------NNLYFLLNTAQQTLFRQVDQQA-LQLVGVSAAQITALHHLQSMNGCMQADLGDALGLGKAATSGMVSRLEKNGLVKRLPSPTDGRGYKLMLTEDGEKAIVRSRPLLNQLNVILEDGFKESELVVIRRFMHTVVDKLTA--- ->tr|A0A1W9TC88|A0A1W9TC88_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_123 GN=B6I22_06015 PE=4 SV=1 ------------DCIFFQLAKAHQAGARFWTRKL--SGFNVTAVQGMVLGFLSENDRITARKLGERTMLDSATLTGILDRIEKAEFIERRPHPEDRRALQVCLTSEGRVLGETLLERSIAANREFLGRLTDEEQMILRILLKKLRGKDSG--- ->tr|A0A0P1H3P4|A0A0P1H3P4_9RHOB Transcriptional regulator SlyA OS=Phaeobacter sp. CECT 5382 GN=slyA_2 PE=4 SV=1 -----------------LLNRIVHRYNQSVKA--DIKGAGLTTVATRIIVSLKVYGQMTVNELCVHAIAEQPAMSRALDKLEAEGRITRRVSEEDSRSRVVELTESGAALYEQVWPVLTGANETMLKGLSSEDREALQRILMTVLKNIRK--- ->tr|J0JNM3|J0JNM3_ALCFA MarR family transcriptional regulator OS=Alcaligenes faecalis subsp. faecalis NCIB 8687 GN=QWA_02660 PE=4 SV=1 -----------------QMATIIYKLDqTLRST--TLREHNMTYVHFRVLQYLWDKDGCSIGEIAKAIVVHQPVLSRVLDQMQDRGLVQRRTDETDSRYMRVFLSDTGRERYAQVWPPAKAMIDNALSVLTVDERQDLGRMLRSMATHLAN--- ->tr|A0A1E1EYR6|A0A1E1EYR6_9SPHN MarR family protein OS=Sphingobium cloacae GN=SCLO_1003120 PE=4 SV=1 -----------------LVNRLASVGLAVQNR--TLGQQGINTVMLRTLSVLHITNGLTVNEIAVQTFVDQSTASRTIDAMAASGWVERRIPETDMRRREIILTEAGRKLLRDCWPLMEGHCARLTDGIHEADLAACRRVLARMTDNLRQ--- ->tr|A0A1Q4BKR2|A0A1Q4BKR2_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_07275 PE=4 SV=1 -----------------MLNKVIKVINSALDR--ALQEHGMSVAEWRVLATLGFSKIDRPADIAKFTGIDPSTLSRAFDRLEAQGYVERSRPPGSRRGYSMSLTTLGRSVLRRAIKIVRTQHDELLQLMDKQQAKHFLKSVAFLYQKMGQ--- ->tr|A0A1H7NHM7|A0A1H7NHM7_RUMAL DNA-binding transcriptional regulator, MarR family OS=Ruminococcus albus GN=SAMN05216469_11549 PE=4 SV=1 -----------------FINDISRLFMHRVRR--ECERCGISHGHHKLLMELFQNEGATQLQLVQRTHLTAPTVSVALGKMESEGLVRREADTEDMRQVKVYLTDEGREKVGQVRSIFRGADADMVKGIPQEELDAMTATMRKILKNLLE--- ->tr|A0A1V5PQV8|A0A1V5PQV8_9CHLR Transcriptional regulator HosA OS=Chloroflexi bacterium ADurb.Bin360 GN=hosA PE=4 SV=1 -----------------LLAQVSRLHHERART--RFSALGLHRGQPQLILALSEKDGRTHTELAEYLHVTPATVTKMVQRMENSGFVQRQPDADDQRISRVTLTPAGRQAGEQLSTLFDTLDAETFAGFTSQEREFLQQLLRRVRDNLLR--- ->tr|A0A0R1SPK2|A0A0R1SPK2_9LACO Uncharacterized protein OS=Lactobacillus diolivorans DSM 14421 GN=FC85_GL002455 PE=4 SV=1 -----------------------SVINRLVRNQIThlLSSVDLSDNNFMLIVKIHDNPGLSQKMLVHQIYRNHSIITKQLAKLKKLKFVDVVVNPKNKREKQIFLTNKGESAYLEIVRVSPIVNKWIVEGLTENEAAQFTKLLKKIFENKKD--- ->tr|H3NMR1|H3NMR1_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_00622 PE=4 SV=1 -----------------------NAIHWSSIAGRCqtFEEYDILGHQVSYLIAIYKYPGLSQENLRDAMFVNKSTVARNVKTLIDKGYAKSEVDSEDKRVNRIYPTQKLIDFFPKIEKHLDEWNNEILSDLSYEEKVTFENLLKKVALKAVN--- ->tr|G8QQH9|G8QQH9_SPHPG Transcriptional regulator OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 / DSM 22778 / Grapes) GN=SpiGrapes_3163 PE=4 SV=1 -----------------------SAIAKYWCIYAHknLQSLEIVGSEHSVIMYLSIQNNISQDTLSTQLVLDKGTIAKILVKLEQKGLVSRVVNEQNKREKIVSLTEKGEEEVKSVYAIVNLWETELLEGISETDQTIFLDVLTSMTERAKS--- ->tr|F3A5U3|F3A5U3_9BACL Uncharacterized protein OS=Gemella sanguinis M325 GN=HMPREF0433_00168 PE=4 SV=1 -----------------------ITILEVMRNYTKepLAKLGITHGHFITLLYISENEGVTQAQLSEIHRKDRNIVSRNINVLEEKGFVIRKRGIVDRRSFSIHLTDLGHSVVSTHKNLIKESEQEALSNLSKDEIAIFYSLLTKIA-------- ->tr|A0A1C6IJI0|A0A1C6IJI0_9FIRM MarR family OS=uncultured Eubacterium sp. GN=SAMEA3545368_00914 PE=4 SV=1 -----------------------SQIYRRTQIYMNerMKDMELSGALAPFVMITYENGKMVQNKFCELMDMSKGTVAKTMNKLEEHGYVTRCGNVEDGRSIDVYPTDRAEEVYPYLVRAGEDWVEIMTEGMTEIERNIFLELLKEVSGNISR--- ->tr|A0A242CVR8|A0A242CVR8_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_003517 PE=4 SV=1 -----------------------SVLYRKMQMGFDklLAPLGLTNGKVMFLFCLDDNGAITQNQICKELDMDKSTVAKMLTKLEKEGFIYKRVNPDDSRAFLVELSAKAHEIMSSAREAHDTWVQLVTSDLTDIEKNIFIELVHKVSQKSIL--- ->tr|A0A1Y3TWW6|A0A1Y3TWW6_9FIRM MarR family transcriptional regulator OS=[Clostridium] lactatifermentans GN=B5G26_15435 PE=4 SV=1 -----------------------SILYRKSHMWLNncCLQHNLTAAQAVVILIICDFKQLTQDEITKRLALDKSVIAKTVTKLVELGFLIRTTNAKDKRTFDIQPTEKSWEVYPFIKEEIEATFQRMTQRMTEKERAEFKRLLSMAAEASID--- ->tr|A0A150XI61|A0A150XI61_9BACT Uncharacterized protein OS=Roseivirga spongicola GN=AWW68_06525 PE=4 SV=1 ----------------------------------GLKAYSVTPEQWQVLIILWNHGSVTPTEISRVTLQDLPSISRMLVRMEKNGWIVRVENEDDGRSFHVQLTEKGRKSKNEMIISLDNHFNSYLQEVPKELHDGIRNELLQ---------- ->tr|A0A1V6LUA3|A0A1V6LUA3_9FLAO MarR family transcriptional regulator OS=Flavobacteriaceae bacterium HSG9 GN=BUL40_03665 PE=4 SV=1 -----------------------KIQDAYLRAFDN-LDVHMTIEQWVIMHQVYNmGEEASQSEITQLNFRNRATISRVIGGLERKGWIKKTRFEGDLKRFKLELTTVGTEIVDKVLPEALRLRRLAVKDLNPTEFANFLKVLDTLGANY----- ->tr|A0A0R1LEN9|A0A0R1LEN9_9LACO Transcriptional regulator OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL001011 PE=4 SV=1 -----------------SIGLIARATSSMGN--HLFSQQNLQNNQFLYLLHILDSPGITQAELAAQLHVDPSTCLRTVRKLITGGYLVRQADPADKKRKCLVPTEQAHAFYPQLQHYEQTLLTVGTTDFSAGERLMLEELLARVATNIER--- ->tr|D4MPF6|D4MPF6_9FIRM Transcriptional regulators OS=butyrate-producing bacterium SM4/1 GN=CL3_04260 PE=4 SV=1 -----------------CMLDICRCLDAIRE--GQFAKFGLTRGQHSFLTRISENPGINQENLSYLLKVDRSTTAKALKKLIEKGYIKKIHPENNKKEWILFVTEEGASLNEKMEDLVINPLIQLYQGVSDREITRLYKTMSLMDTNIVA--- ->tr|A0A0R2FCQ7|A0A0R2FCQ7_9LACO MarR family transcriptional regulator OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL001657 PE=4 SV=1 -----------------EIGAITRLIQTKSN--AEFRGLGLGNNAFIYVIRACEQPGMFMGELADSVQIDRTTAFRTIKKMVATGWFELKADATDQRLRRVYPTKKAKAVYPRLHAFEQAQSDYLLSGLTPREQTRLTALVKKLKVEEL---- ->tr|A0A1V4SU86|A0A1V4SU86_9CLOT HTH-type transcriptional regulator SarZ OS=Clostridium thermobutyricum DSM 4928 GN=sarZ PE=4 SV=1 ----------------------------------KLCEYGIGCSEYMYIISMPIDSSVNLSYLSNELGVDPALTTKVINSLVKKELVYKHRSENDKRSFEVSLTEKGKQIKPIIRKVLDEWTELMTKGMDNKTKESIIENLEIMVENIK---- ->tr|A0A1Q4BC56|A0A1Q4BC56_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_26610 PE=4 SV=1 ------------------------------------KSFGVTHAQFAILQTVHLAPGLEQREIAEAAGYDSVTASHMIRKLEAMNLLRRDKGSRSRRGNSLHLTTAGAEKLKEMEPAIARVQERLVERLPPEKRKLFLQLLSEITGIENV--- ->tr|A0A1M5MR97|A0A1M5MR97_9BRAD Transcriptional regulator, MarR family OS=Bradyrhizobium erythrophlei GN=SAMN05444169_4183 PE=4 SV=1 ------------------------------------AQFEITPLQYSLLSALAVRGTADQTTLAVDVSLDRTTTTGALKRLQARHFIERAVRRDDRRARVCRLTQTGGALLARMETAAREAHRDTLASLSKSEQKRFVSLMQQIVAASSL--- ->tr|A0A1M2Z0H9|A0A1M2Z0H9_9RHIZ MarR family transcriptional regulator OS=Rhizobiales bacterium 65-79 GN=BGN87_20515 PE=4 SV=1 ------------------------------------GEADLKPGWFAVLSLIHDNPGITPLVLSRASGRDKSTITPVLRDLLRNHLIEQKPMPADKRSYMLSLTDAGKGRLKELTEHAMEHDRVLDEIVGDS-KPELLRILRLIISSVD---- ->tr|A0A1P8W9D6|A0A1P8W9D6_9PLAN Transcriptional regulator SlyA OS=Fuerstia marisgermanicae GN=slyA PE=4 SV=1 ----------FEESIGYWVTISALAFRKALNEDLAPHGI--TFRQSQVLGWLVLEGELSQSELAARMEVEAPTLAGLISRMEAAGLVARHSCPNDGRRKIIRIEEA-------AKPVWEKIAECArrlraaaTTGLSEEQVRQLLDWLRVVHENLSQR-- ->tr|A0A0R2LFW9|A0A0R2LFW9_9LACO Uncharacterized protein OS=Lactobacillus kimchiensis GN=IV57_GL000093 PE=4 SV=1 ----------------------------------LLKPYQITSGLWPYLAVLQASSNMTQSNLTLELRNDRAMTARSIAKLKQLNYVTGEPASHNKHMQYLRLTSKAETIMPEIRQVVDNAMLEMTRGISETDLQITQQTLQQILFNLTK--- ->tr|C6L8X2|C6L8X2_9FIRM Transcriptional regulator, MarR family OS=Marvinbryantia formatexigens DSM 14469 GN=BRYFOR_05061 PE=4 SV=1 ----------------------------------------KNATQTHILYFLFHDga-CRKiyQKDIEEALNIKSASLSVQLKKMEKSNMIARRKVSGDDRLKEVCPAPAGIALKEQINDEINLLEDILTEGICKKDLDTFYDVVRKMSENI----- ->tr|F9P7G4|F9P7G4_STRCV Transcriptional regulator, MarR family OS=Streptococcus constellatus subsp. pharyngis SK1060 = CCUG 46377 GN=ANG5_0941 PE=4 SV= -------------------------------------IEFMAGPQGQVLHFVnhREDc-GKMtfIKDIEQELGITKSVASNLMKRMVRNGLIYLEVSEADKRAKIIRLTSESKERMNKIRDFFDEMDRCLLTGISEEDLVTFFQIMGRFYQNI----- ->tr|D1AHW0|D1AHW0_SEBTE Transcriptional regulator, MarR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_1482 PE=4 SV=1 -------------------------------------DKNLTGMQLAVLLFVgyHnKLdk-NKDifPNDIEKKFNVRRSTVTTILKKLVKDGYITQIRASYDERYKRLFITEKSELIYSKIQQAQIEGEEIVSKGLSQEKIDIFFEVANKIMENI----- ->tr|A0A0P7VYU1|A0A0P7VYU1_9RHOB Transcriptional regulator, MarR family OS=Rhodobacteraceae bacterium HLUCCO07 GN=HLUCCO07_13750 PE=4 SV=1 ----------VSDYLLYLLAAASEAASAQFHAH--VRSHGLRVPEWRVLAWLHDRDGAMITRLARISLIEQSRLTRIIIQMEERGLVLRKGDTRDRRRVRVHLTEKGRGIAETLVADARAHEAALLAQLEGGDGARLKPALAALLARLDPD-- ->tr|A0A0N0IET7|A0A0N0IET7_9BURK MarR family transcriptional regulator OS=Burkholderia sp. ST111 GN=ADM96_23870 PE=4 SV=1 ----------LEQAIPFLLTRAGGRMGNAFAKA--LKPFGLNLSEWRVCASLLYVPHQTLSELSVHATSDISALSRIIDRLESQELVKREKSTTDGRSIRIALTSKGDELALRIVPVAKQHESVILSGFTANDVQVLRTMLLKVYENAGAL-- ->tr|A0A120LTW7|A0A120LTW7_9SPHN Transcriptional regulator, MarR family OS=Sphingopyxis granuli GN=SGRAN_0812 PE=4 SV=1 ----------VDRYPFYLLNRLVSRYNSIIDAR--LRAIGLDIPSWRVLMILGEESPRGAREIAQAAVINLSTMTRIIQRMTAAGLVTATPSREDARVTLVALAPAGEAQLAEARLATAPIYAHLIAGLKAEEFEQLIALLGRLHDNLEPL-- ->tr|A0A1C3WUA1|A0A1C3WUA1_9RHIZ DNA-binding transcriptional regulator, MarR family OS=Rhizobium lusitanum GN=GA0061101_11781 PE=4 SV=1 ----------LEDRLSFLTNRVASAINERFVLK--LQIHSLTIPMWRVLVVLHDFGESKLVDLSSLTSIDASTLSRLTEGMHERKLIRKVRSTKSKREIVVSLRSEGKGLVDALIPQAIELDTFMLAGLSESDMAVTRRALRSMYEQLTAA-- ->tr|A0A1Q4BBZ4|A0A1Q4BBZ4_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_25755 PE=4 SV=1 ----------VRLNVPYLLGRAANGLLGRLTEV--LKQQDLSLGMWRILALLYAQSPLRFSALFTLSSMEPSTASRFINELLQRGLIAKKKSKTDARGVLLSITRAGQQTVRSLLPQVAVMEKDTLAGFSEDEVYLARRLLQRMCDNVSPL-- ->tr|A0A1W6ZJS5|A0A1W6ZJS5_9RHIZ Uncharacterized protein OS=Pseudorhodoplanes sinuspersici GN=CAK95_00250 PE=4 SV=1 ----------LDDLLPYLMNRLIARMNQNLAEA--LRERGFTFQDWRVLAVLAAHEGANLTELAEATVIPQPSVSRLVANLTRRGYIERQNGATDSRVVHLHITAKGRGIYNKMLPLAVKEYRAATKGFSAKEYDQLRESLLRMMKNRKVS-- ->tr|A0A1U7DLH2|A0A1U7DLH2_9RHOB Uncharacterized protein OS=Xuhuaishuia manganoxidans GN=BV394_14790 PE=4 SV=1 ----------NADRMAHLLKLASKATSRALQDR--LARHDIAYSHWTILRILWNQDSLSVTELSLRASIAKPATVTAVQALDKLGYVTRRKRDGDKKTVYIELTEAGRALEAELVPLAVEVNDIALRGFRETQKAALRKMLSKVIANLDNA-- ->tr|A0A1Y1PVX2|A0A1Y1PVX2_ALCFA MarR family transcriptional regulator OS=Alcaligenes faecalis subsp. phenolicus GN=BV899_12925 PE=4 SV=1 ----------HDTFIPYLLNRSTSALNADFQTL--LRSHELTLLHWRVLAFLNETDGLGVSTLAQYTDVDQTTLSRALVVMENAGHLSRQPDPLDQRRVLIHLHEQGRQHFLRVLPAALDIHHRAIQGFSAEELTQLRQFLNRIRANINGD-- ->tr|A0A219B474|A0A219B474_9SPHN Uncharacterized protein OS=Pacificimonas flava GN=B5C34_06555 PE=4 SV=1 -----------------------------------IHGLGLNRTQWRIITQIARNPLVSQTELGTILELKKATIGLAISSLENAGYINRLRSPDDQRVWQIVLLPKVKTALPVLRDAADDVYKHLWGILSKEQQDFLIETLERMAARTSEL-- ->tr|C0QDU6|C0QDU6_DESAH MarR OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=marR PE=4 SV=1 ---------------------------SFSASLEqRLGGSGVSRVQFMALAHLIALGTMPQKDLAQLLSITSASTVRLVDRLTRDGWAERIPAQDDRRVKLIVPTPKAVEAWEVMSDHAEKITAKAYVGLTREEIDGVKAVLKKVRENLKK--- ->tr|A0A1J0WNS6|A0A1J0WNS6_9RHOB MarR family transcriptional regulator OS=Sulfitobacter sp. AM1-D1 GN=BOO69_20495 PE=4 SV=1 ---------------------------LMRGAFErEIEraQIGVTAAEARVLAHMSVCGGMRQNILADRLGCAPMSVTAFLDRLERAGLIERAADPDDRRAKIARLTPDAQPILEQIQLAGERARGIAFAGVRPEDFEVFRAVCLQLRANLEE--- ->tr|A0A1C8ZVY4|A0A1C8ZVY4_9CREN MarR family transcriptional regulator OS=Sulfolobus sp. A20 GN=BFU36_01220 PE=4 SV=1 ----------------DLIVGLTRKVNKEADKALEELGLSY--FEYKVMCALEEEGKVPMSRVAEKYMLTKAGLTSIIDRLEEKNYVTRIRSEEDRRVIYVELTDKGREKLAQSRKIFGEVIERFMKKLDNNELDNLEKILTKLIG------- ->tr|A0A1F5UXW7|A0A1F5UXW7_9BACT Uncharacterized protein OS=Candidatus Firestonebacteria bacterium RIFOXYC2_FULL_39_67 GN=A2452_10990 PE=4 SV=1 ----------------EYPKKIMKKFGSPIDEDLMKLNLDM--PHVAILDIITHSKIEPMmSEIGKKQGISKAMITRIIDTMEEKGLVSRVEDPKDRRIIRIHVTKIGKGVISKIESHHRNKLKSFLESLSSSDRNLFVNAMRvthKIFDKYGD--- ->tr|A0A1W2G4V1|A0A1W2G4V1_9EURY Transcriptional regulator, MarR family OS=Picrophilus oshimae DSM 9789 GN=SAMN02745355_1320 PE=4 SV=1 ----------------KEFIKTWKIWYRASEKNLINLGIST--VEYRILKNLYERGPLPMIELANINMVTQGWITGVVDKMEKNGYVKRDRSQNDRRVINISITEKGIEFFKHIAELHLNYIDMTLQDFTDYDMNEMIKLLQRVQENVNK--- ->tr|A0A218ZTW2|A0A218ZTW2_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon B_DKE GN=B2I17_03725 PE=4 SV=1 ----------------RTMKDVWKLWYRQAERNLSLVGLNN--MEYNVLRILSENNAISMVQLANLSMVTQGWITSMVDKLEERKLLERSRSTDDRRIIMIQITNAGKRLMSRAQQAHVKFLEESIKGLNETEISDLLGLLEKLKASLVE--- ->tr|A0A150WMT8|A0A150WMT8_BDEBC Uncharacterized protein OS=Bdellovibrio bacteriovorus GN=AZI86_01015 PE=4 SV=1 -----------------QMSRTMLSMKRYLIAEFEASQSPLSFEDWMNLLPLVENGSMSHRDLAHVLGKDKTTISRLVSQWIEKGYVKTEHDTEDQRIKHLTLSKEGKKLHNSLNSVVQKADRGFLKGLEQSEFDLFKKVLTKIQGSL----- ->tr|A0A1I3N0W8|A0A1I3N0W8_9SPIO DNA-binding transcriptional regulator, MarR family OS=Treponema bryantii GN=SAMN04487775_11182 PE=4 SV=1 ----------------------------FINEL--LKESQLTFADSIFLCNIAVNSGCSQEDISLNLHIDRAAVARSIRKMEECGFVLVSRDKNDSRKKILELSDNGKKLYGMVNSANEERLSALLKGCSQKNAEIFFSVLETCAKNSVD--- ->tr|F2BSJ9|F2BSJ9_STRSA MarR family transcriptional regulator OS=Streptococcus sanguinis SK1057 GN=HMPREF9394_1489 PE=4 SV=1 --------------------------------LLNQDPEaLYRSEQGKILTVLWNsETgCATATDIALATGLANNTRTTMLKKLEEQGLVTFSQCGLDKRKKYVKLTEQGWSQKEVGHRVSQKLDAIFYKGFSEEEIRQFESYQERILANLKEK-- ->tr|R6R607|R6R607_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:449 GN=BN661_01737 PE=4 SV=1 --------------------------------LALKF--NLTDSTMKILYAICDiGEPTQIIDICKHTATSKQTINSALRKLEIENIIYLKFS--DRKSKNVFLTDKGKILVEKTVKKIILIENEIFNSWSKEELEVYFKLLEKYNYQFKDK-- ->tr|I2J8Z9|I2J8Z9_9STRE MarR family protein OS=Streptococcus sp. SK140 GN=HMPREF1116_1098 PE=4 SV=1 --------------------------------LLNKEPDaQYRSEQGKILTILWKqELgCATATDIALATGLANNTLTSMVKKLEEQGLVTIQPCTQDKRKKYISLTDLGWAQKKLETVLVGNLERFSTKAFQIKKSENLRPIKRE-LSQI----- ->tr|A0A1G3YG68|A0A1G3YG68_9SPIO Uncharacterized protein OS=Treponema sp. GWC1_61_84 GN=A2001_14020 PE=4 SV=1 --------------------------------LMKDAGLgDIGSGEGRLVYLLWRDGPMRQGELAAKAGIDKSTLALTLARMERKDLVERRQDDDDGRAVIVSVSASAALRAPSFDLVSNEMNEFFYAGLAEGEIDAFEATLKKILLNFRNE-- ->tr|A0A143WCL8|A0A143WCL8_9LACO MarR family transcriptional regulator OS=Lactobacillus oligofermentans DSM 15707 = LMG 22743 GN=LACOL_1325 PE=4 SV=1 -------------------------------------------GQGHLLSVLMEHDNLSQKELADVVHIRAASVTDLLEKMEHEGLVIRTKDEKDRRITRVSISDKGRQFLIKNNLIRHEVNEVVYGDLNDDDLEQLDMIYQKIINSLSK--- ->tr|A0A1V5RLW4|A0A1V5RLW4_9CHLR Putative HTH-type transcriptional regulator YusO OS=Chloroflexi bacterium ADurb.Bin325 GN=yusO_1 PE=4 SV=1 ----------------------------------HIRqaateQFGIGIEQFQILRHIRRGR-SSVSELADARSISRPAVSQIVDALVNKGLIVRTPDAHDRRRTRLALTAAGDALLDAVFKDTRRWMMQLFSRLDDEELQELVRGMHSLRKAQPV--- ->tr|A0A0B8NY79|A0A0B8NY79_9VIBR Uncharacterized protein OS=Vibrio ishigakensis GN=JCM19231_748 PE=4 SV=1 ------------------------------------HKVDFSPLEHVAMSNIRELGGASQQMLVEAMQKDKTQVSRIIARLHRQDLIIKTPDPFDKRSVNLTLSDNGETLLNSLDKVESEMVENMLQGFDATEVQTLCDLLSRLNNNLK---- ->tr|A0A1C3DRE3|A0A1C3DRE3_PHODD Uncharacterized protein OS=Photobacterium damselae subsp. damselae GN=A0J46_16615 PE=4 SV=1 ------------------LARLMMMTRSQIQQQMKRHDLPCNVESVRTLDELLNHPGINSHQLCQLTGFDKAHIARKVTEFEQKQLVYRQKDPKDKRITQLYLTAEGMDVARCCITLRNQTVLELMAGIQPNALESLNIFLESFKAENQK--- ->tr|A0A133KSD5|A0A133KSD5_BACCO Transcriptional regulator, MarR family OS=Bacillus coagulans GN=HMPREF3213_01746 PE=4 SV=1 -----------------------------------LAQFGLSYSLWQVTFYVRNFGPCTLVEICKYYQVEKPNVTRIVQKLEEQGIVEQIPGK-DRREKVIRMTERGENLYRQCRAEITGLEQQAMKGIPEAEQEMVFELLPQIRDNLDH--- ->tr|A0A179SMR5|A0A179SMR5_9BACI MarR family transcriptional regulator OS=Bacillus litoralis GN=A6K24_10325 PE=4 SV=1 -----------------------------------LQKHDLYSSQWSILYCLKINGPMTQSDIWRYLVVEAPTVTRTLVKLEESGWVKRTQGS-DKRERLVSLTDKAIQHLPAVEDEVKSFEQRMVKSLSNEEKDYFFHLLNKLGTTSLE--- ->tr|A0A0M0ES55|A0A0M0ES55_9BACI Uncharacterized protein OS=Bacillus butanolivorans GN=AKG34_03605 PE=4 SV=1 -----------------------------------ITALEIYHNQWTILNYLKNCGYSTIPDICNYLDVDSVIITRSVNSMEQNTMIKQVPGK-DEQEKRIELTPKGKEVHTKCLKIAEKIEGKALDGITEEEQDLFFQTVLKILNNIRN--- ->tr|A0A0P7N220|A0A0P7N220_9BACI MarR family transcriptional regulator OS=Lysinibacillus sp. ZYM-1 GN=AO843_04610 PE=4 SV=1 -----------------------------------LEPYQLYSSQWAVLRFLKDKGPHSFVDIANFMSIEKPSVTKLVHKLLELGYVETMAGK-DKREKLVHLSAYGEELVQEIKSHLKPFFEHALAGVAQQDIEIATQVFARIYMNINQ--- ->tr|E0RIX1|E0RIX1_PAEP6 Transcriptional regulator OS=Paenibacillus polymyxa (strain E681) GN=PPE_02119 PE=4 SV=1 --------------------------RREIETA--LRPLGLTSPQSQTLYILAMSPGVTNTDLEKLLLIDKSSVTSLVNGIVKKNWAVRKSHPEDARMKQIYLTEEGLEIHKIAERTIEAIKSSVGETLSVGESETLRGLLKKILHDYR---- ->tr|G5HTX4|G5HTX4_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_06036 PE=4 SV=1 --------------------------TYYRNVK--MHALGLTSVQGDAIRAILHNPGITASRLQDLLGLSQSTTAGIVARLEHKGFLSKINNKLDGRELFLTPTQRCLNLEEQLKETALETQRLLIKGMTDEEQFEFNRLLELALTNMS---- ->tr|F9TAZ0|F9TAZ0_9VIBR MarR family transcriptional regulator OS=Vibrio tubiashii ATCC 19109 GN=IX91_23340 PE=4 SV=1 ----------------------------YVSHLL--EKCDVSFSQLPFVTCLYKNPGITQEALSRKVEVDKAMCSRVLKQLEQKGLVARKISPQDARAKLIYPTDQLIAKKRDLLRIIKEWNDILTQGLTNEEIETVKRVNQKMIENVQRK-- ->tr|A0A0D4E1D6|A0A0D4E1D6_9ACTN MarR family transcriptional regulator OS=Streptomyces lydicus GN=T261_8005 PE=4 SV=2 ----------------------------IAGQLL--RRVGLHLGQELVMMHLWELGPQRQTDLVRLIDSDAATMTRSIKRLENAGFVRRRPCPDDKRAVIIEPTAASQALRREVERIWAELEGASTGDLTPDQQAETLNTLRRIEDSLART-- ->tr|A0A1X2AX62|A0A1X2AX62_MYCPR Uncharacterized protein OS=Mycobacterium peregrinum GN=AWC21_20580 PE=4 SV=1 ----------------------------WGSEML--LELGLHPGQELILMQLYDRDGQTQSELQQALGVDHSTISRAIKRMQLSELVARAASDNDRRAKEVWLTDKGLALRKPLERLWTSLEQCAIEAVPPSRRAEFARSVAKLEQTYTSA-- ->tr|A0A1V5HUY4|A0A1V5HUY4_9SPIR MarR family protein OS=Spirochaetes bacterium ADurb.BinA120 GN=BWY96_02560 PE=4 SV=1 ----------------------------FIEREMErRGIEGMAPSFGDVFMIVAARGPLPMKEIARLTYKDKSTITGVVRALEKAGYLSRSGDPADGRAALVSITPEAVKITPALRMASTSMNERLLDGLSERDCRTLFRLLGRLGANLKSA-- ->tr|A0A0Q5TBQ7|A0A0Q5TBQ7_9BACT MarR family transcriptional regulator OS=Dyadobacter sp. Leaf189 GN=ASG33_01800 PE=4 SV=1 -------------------------------AQLVQEGIPVLAEQLPILMVVYfqE-HAMTQQDIANVLQKDKAGIQRSVQTLHKDGFLKIESDIEDKRKNMVTLTASGKFVCERIQALVIAFDNQVMEHFTEDERKTFMGFLDRVTAVIE---- ->tr|A0A0R1Y293|A0A0R1Y293_9LACO Uncharacterized protein OS=Lactobacillus pontis DSM 8475 GN=FD34_GL000153 PE=4 SV=1 -------------------------------------QPSNFRGQGRIIDLIAHHEGCAQRELAVLAGVKPGSLTEVLERLERNGYVSRQRDERDRRVIRVALTTRGRTFHADLVAKRTAFARRLLTDVSPKEREQF----IRVVDKMQT--- ->tr|A0A089LX40|A0A089LX40_9BACL MarR family transcriptional regulator OS=Paenibacillus stellifer GN=PSTEL_12650 PE=4 SV=1 -------------------------------------AEGLTSDQFTILRLIHGQEKCTSTFLAEACCVGKSSITAIVNRLVEAGLIDRTRDESDRRQVYLTISSLGSQVFDEANQNVSEILTPYLLHFDEDQIEQFISMFEKLADLMKE--- ->tr|A0A0G0LZP3|A0A0G0LZP3_9BACT Transcriptional regulator, MarR family OS=Candidatus Daviesbacteria bacterium GW2011_GWA2_38_24 GN=US86_C0003G0097 PE=4 SV=1 -------------------------------------QNHITHSQWFVLKVIDHLENPRVKDVSEALSMSSSATTQLVEPLVQAGFVLRKEDPKDRRLVQLQLSLKGKKQIAAKKEECIAEMGMIFEGLTDKELEEF----VRLHKKITL--- ->tr|A0A1W6VX04|A0A1W6VX04_GEOTD HTH-type transcriptional regulator MhqR OS=Geobacillus thermodenitrificans GN=mhqR PE=4 SV=1 -------------------------------------RVGLNLTDYKVLGIIPF-EGLTAGEIASITGLSTGMVTTVVDRLEKKNFVYRDRDPDDRRKVIIKANFEKIgSELGPYFQSFGQEIGKVVSKYSPAEMEVINDYIRKTTEVFKR--- ->tr|A0A218ZM79|A0A218ZM79_9EURY Uncharacterized protein OS=Cuniculiplasma sp. C_DKE GN=B2I18_04105 PE=4 SV=1 -------------------------------------KENLSFTGFFVLSTLSKGGRMKSSDLALRLGVTKPSISHIIDNLESKGLVIRQYGMDDRRAIYIDLSVKGKLMLEKLYNVKSMALKAMG-EIDQQTIEGFlqfVNMLAKNVHEIRE--- ->tr|A0A1W9ZB32|A0A1W9ZB32_9MYCO Uncharacterized protein OS=Mycobacterium arosiense ATCC BAA-1401 = DSM 45069 GN=BST14_20465 PE=4 SV=1 -----------------------------------FSDSGLNLAEATVLAHLV-DGALTQSELARRVGTSRARIGGLIDSLEPRGAVRRDGHPTDRRVWLVNLTDKGHAMWESTVAADRTLRKHLRKGTTAQQRERLDEVLTLIQENALAFL- ->tr|A0A0R1GMA6|A0A0R1GMA6_9LACO Uncharacterized protein OS=Lactobacillus parabrevis ATCC 53295 GN=FD07_GL001510 PE=4 SV=1 -----------------------------------LAPMGINRSAWMALYYIDQHQQIRQRDLAELVGITGPSMVKVVNQLNTADLITVAVSAQDHRARLLALTPAGTALLTKSIPLAEAFRAQVTAGIPQDDLDTLDRVMEQMMANAND--- ->tr|W6T422|W6T422_9LACO Uncharacterized protein OS=Lactobacillus fabifermentans T30PCM01 GN=LFAB_16475 PE=4 SV=1 -----------------------LKFEAARNAFYEQ--YGMTGSQADVLEFLKNQPAQtaPIGDIVGALQVSYATTSGLINRLEKKELVERIVNPDDQRSFLITLSDKTTVAeiFAAENAALSVVDQQLTRDFTPAEFVTFVRLLRQLNHN------ ->tr|A0A0R2B6X6|A0A0R2B6X6_9LACO Uncharacterized protein OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001024 PE=4 SV=1 -----------------------HQLKYQLNQALLQ--EDLTVQQWALLQQLMLERPLTAVQLANRLDMDKPTVSGIVKRLVEKDFLTKQANPTDQRSQLLNLTTAGQTAAITGQGISNQILDAIIAPLSTEDQQLLNQLLGKLIPTKE---- ->tr|A0A1F3RVU5|A0A1F3RVU5_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_16560 PE=4 SV=1 -----------------------LGMQIqQINQKM-EHEIGVSLTQWSLLRCMVDNPTISALDLAQELGVQPSTLTQILKRLERKKYIFVTKDPLDARRKLLSLTRAGNSTLLEANRTIAALEKhvKFSNTAVREISRGLTHLL------------ ->tr|A0A1Q4B8X8|A0A1Q4B8X8_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_19380 PE=4 SV=1 --------------------------------------HRITPLQFTFLWILSIEENLSQVELAQRAGITRASATDDIEALKSRKLIRGRRDATDKRKIILSMTAAGNDMVTRLADHAAVTNTTARGELSKQAYRQLFDLLAQVTSNLNAAS- ->tr|A0A1Z5IHV5|A0A1Z5IHV5_9LACO MarR family transcriptional regulator OS=Lactobacillus silagei JCM 19001 GN=marR_7 PE=4 SV=1 -----------------------------------LRHVGIYPGQENILVELLNYGELSQNDLVKRIVVNHSTIAKSVSRLVSAGLATTTKSTADGRITLVSLTSHGQLVANQVKQILDHAELTLLKGLSKSDQQTFISLASQIGSNLA---- ->tr|A0A090AAK6|A0A090AAK6_9GAMM MarR family transcriptional regulator OS=Thioploca ingrica GN=THII_0231 PE=4 SV=1 -----RDFVSQEETVLLSFMHTWQHLDRLGKLFF--PRFGLSDAQFNVLMVLwdYRETGMRQHELASLLMVNRASVGGVIDRMERQVLVQRQRDPVDRRSNYVHITAAGIALLEKIKPVYYALFPPAFANLNSHQQQEFFKLLEQFRQGILQV-- ->tr|A0A0B6WZ76|A0A0B6WZ76_9BACT Transcriptional regulator OS=Pyrinomonas methylaliphatogenes GN=PYK22_01476 PE=4 SV=1 -----KEFHRPSVELLLNLIYTYDVIRSRVAKRI--EAYGLSPAAFNALMIIshYGESGCPMCEIGDLLLVSRPNVTGLIDSLACKGLVERVEKEGDRRFRLVRLTRAGERLLDELLPSHYANVRAMFAGMSDKEKAILSKLLVKLRHEVLRS-- ->tr|A0A1F5UCM1|A0A1F5UCM1_9BACT Uncharacterized protein OS=Candidatus Firestonebacteria bacterium GWA2_43_8 GN=A2044_07410 PE=4 SV=1 -----REIETKEHECVMSIMYTSTLLYKIAYKYF--SGFNITESQFNSLMQLkySEKEGMSQIQLSRRLLVNKADVTGLVDRMEKAKLVERLSAPSDRRVKIIKITKKGLETVKTMESGYFNYVNKVMGGLGKKEIENMVQGLQSIRKNAQGV-- ->tr|D6U0F1|D6U0F1_9CHLR Transcriptional regulator, MarR family OS=Ktedonobacter racemifer DSM 44963 GN=Krac_3086 PE=4 SV=1 ------------------------------SDRQFFASYGVNTRRYWALQHLDEQQGCSMVELSRVLFTDKSNVTGIVDRLESQQLVERKTDPGDRRVILITLTAQGRQLRDHLHGLHEAHICKQLNIVDIEQLAHVRDCLRAFSENIEL--- ->tr|A0A1M3JXJ3|A0A1M3JXJ3_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 44-23 GN=BGO78_09005 PE=4 SV=1 ------------------------------GDRRFFQGFGLSQARFYALLHVQKDPGISLTELSRRLLCTKGNTTRILASLTEGGLLSRTVDPQDQRAYHLEISARGQGLFDQVRAAYQHFNQERFTALTDRQKRMLLDQLQILNDDLVR--- ->tr|A0A101VE96|A0A101VE96_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium BRH_c42 GN=APF82_09245 PE=4 SV=1 ------------------------------------WHTGMSAREWRVLGMLGIVGs-RMPSELADLTGMDRATISRATSRLVHLGYVSRLPNQADNRSQTIELTPAGEAYCQAIVPRMEHSGEECRSLFSAGEFALFIEFLDRMDAAIAD--- ->tr|A5V6K7|A5V6K7_SPHWW Transcriptional regulator, MarR family OS=Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) GN=Swit_1560 PE=4 SV=1 ----------------------------------HLKKNDFTEAQWRVLRAVAEGNCNDQRSVARAALLHPPSVTRILKELAQRGLVERGANETDGRRQIIVATARAREILDEATETNREIVRRYRATFGAERFDRMVSELRDF--------- ->tr|V6HQ14|V6HQ14_9LEPT MarR family protein OS=Leptospira inadai serovar Lyme str. 10 GN=LEP1GSC047_0610 PE=4 SV=1 -------------------SRTRDRIQKFLGRELEKQGIqDIAPAHAGVLFVLSKNGAMRMSELATILDRTNSTATALLDKMEEFGYVIRTKLDPDERVTTADLTEKGKRSVEKVIKASKITLNKLYKGLDETEKAEFVRLLSKIHANFEI--- ->tr|A0A1V4E560|A0A1V4E560_9ACTN Uncharacterized protein OS=Microbispora sp. GKU 823 GN=B1L11_29095 PE=4 SV=1 -------------------DRLREATDRV-AAALATVGNwmfapatrrrimaasGLElsLGDYTLLAQISLHAPVRLSVLAEQMEVDKSTLSPPAKRLESRGFIERQPDPADARAKLVSVTREGKLAIRRLWKARTAAVAALMEGWEPSDIEHLADGLAAFAEAIKKG-- ->tr|A0A231P1I2|A0A231P1I2_9DELT MarR family transcriptional regulator OS=Desulfovibrio sp. MES5 GN=BCS36_09910 PE=4 SV=1 -------------------AAIREQANTLILSSLSERGItDILPAHGAVLNALFKQSPMQMNELAEHIGRKKNTVTGLIATLEDRGYCRRESDPQDARAQLVFLSEKGEAMRQVQDEVSVELLQKIWTGIETQKQIECIQCLETILQNLTNN-- ->tr|R7BHQ2|R7BHQ2_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:882 GN=BN803_02038 PE=4 SV=1 ------------------LGFEIKKMDNIIFRQLKKKlvdaGfDEVTVMHGHILGYLCRHKDKDlyQKDIGEAFGIGKSSVTNILQLMEKKGYLVCRTDDNDGRCKKIVLTQKGEETHAATVKVIDMLHEELEQNVTEEEKRIFLNVIEKMKKNIN---- ->tr|A0A1C5NDN8|A0A1C5NDN8_9FIRM Homoprotocatechuate degradation operon regulator, HpaR OS=uncultured Blautia sp. GN=SAMEA3545244_00965 PE=4 SV=1 ------------------IGRELHTLDMMIGRLVNAyQskvdEkAGINRMQGWIIGYLYRHSDEDvfQKDLEAEFQMARSTASGILQSMEKKQLIIRESIPRDARLKRLVLTPKGMEFQMEIIDNFARIQKALSADIPEKKLEEFYETADMIRENVV---- ->tr|A0A242LEB8|A0A242LEB8_9ENTE Uncharacterized protein OS=Enterococcus termitis GN=A5881_002559 PE=4 SV=1 ------------------IGLKIRILANELNRKAAEIlkedDgEASSSIQMRILNFIHRrnSQQVPvyQKDIEQEFDIRRSTATGVLQTMEKRLFIERKCCEKDNRYKTIILTELGQQKVKENIVKLHKFDELLVQGISENDLTIFFKLMEKLSENSK---- ->tr|R9T4T1|R9T4T1_9EURY Transcriptional regulator OS=Candidatus Methanomassiliicoccus intestinalis Issoire-Mx1 GN=MMINT_05730 PE=4 SV=1 ----------------------------------TLKQYNLKACYLPYLVTLFQKGNATMKELTEQTGTDKSNTTRMISELRERGIVADDRKNKNSKKYNVHLTEQGRELVIKSKNEFESSIDVLFSDLSAEELSTLIKIMKKTQD------- ->tr|R6TWS4|R6TWS4_9FIRM Uncharacterized protein OS=Eubacterium rectale CAG:36 GN=BN626_01523 PE=4 SV=1 --------FTPDKYLGHKINRISRSIDRYFDRKRcsKTEC--IPRSQGMMIGYIMDNQGqnIFQKDIEAKFHLSGATVTNMLKSLEKNGYIVRTPMENDARLKRIELTQKALDHENRVRENIMVIEEAMHEGFSKEEFNMMLGFLDRVIDNMEK--- ->tr|R6Z3M4|R6Z3M4_9FIRM Uncharacterized protein OS=Roseburia sp. CAG:309 GN=BN600_01736 PE=4 SV=1 --------VIREANPVKLIMFINQIHRRKIEKLLDGTG--LHRAQHRMLMTLSDCPVTSQVELANILEVSAATVAVSLKKLEKGGYIQKTQQEQDSRVRFVELTEKGRGVVEESKEIFHQMDAKLLEGFDKEQLEVLQSLLGQMYRNAKN--- ->tr|A6LJB1|A6LJB1_THEM4 Transcriptional regulator, MarR family OS=Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429) GN=Tmel_0135 PE=4 S --------FSL---AFLLFSEIEKLKFQILRSEMEKYK--LHPGQIPMFFIINKFPGITQKEIAEHMMVNTSTVAIMLKRLEKAGFVKKEIDENDRRYFHVYLTDKAKGIHDKLIKKVKEFEKMCFSGLSDLEMKELENLLKKIVNNLEA--- ->tr|V8C438|V8C438_9FIRM Uncharacterized protein OS=Ruminococcus lactaris CC59_002D GN=HMPREF1202_01584 PE=4 SV=1 --------LGM---TAHKIG-------KLAQTMYAEYD--LNKSQSMILFQLHRDGRISQKELAQKLNVSAPSITSMIQKMEKSGYIVRNVDEKDQRMMRLDLTEKGQACIEHVKAIAEKMDEIAFTGISPEEKMLLRRILFQICENVEK--- ->tr|A0A1H6S7P6|A0A1H6S7P6_9LACO DNA-binding transcriptional regulator, MarR family OS=Sharpea azabuensis GN=SAMN04487834_10145 PE=4 SV=1 --------FAN----FRRIGIAYR---NAASRQLNDMH--ITHEQCALL-YLIEQSDMTQKEIAQKLKISEATLSGRVKRLEKMHYIERVQDQNDKRKYDLFITPSGKKALDEAKSIVDRLSKQCFEGFDDQDFALLMSLFQRVYKNLEK--- ->tr|A0A1M4M9F8|A0A1M4M9F8_9FIRM MarR family transcriptional regulator OS=Proteiniborus sp. DW1 GN=DW1_2743 PE=4 SV=1 ---------MIETDVAMQLRETYQKITQILQHKVDEYG--LTFGLLFLTMLIDKKPDASQKELAKIMRFTEGAMSGAVKRLINLKMIEQVPLESDMRYNRLVVTELGKSMIDDYRDYVVKIYQDMFKGFSQEELSKLNEVLAKLNHNLTN--- ->tr|A0A1Y4P1A0|A0A1Y4P1A0_CLOSC Uncharacterized protein OS=Clostridium saccharolyticum GN=B5F06_06290 PE=4 SV=1 --------KGLLGRVMEKCAVTARLHQNYLRREMGKTG--ISKSQRQLLLYIEKNPGATQREIAARRNVSTASVAVAVKKLEKEGYLIKDTDRTDSRRSCLRLTCGGQKVADESKRLFEYTEASMFSGFSEEEILQFENFLNRIIKNGES--- ->tr|A0A1Q6CJ62|A0A1Q6CJ62_9GAMM Uncharacterized protein OS=Thalassotalea sp. PP2-459 GN=BI291_11520 PE=4 SV=1 ------------------------------------GEFDLSRQQWRVLAILATHAPINAKSIGTLADLEKMPTSRAIKGLLAQQLIIRVNSQTDKRAQLLSLSAQGDLLFKQLVPLVSQQEEALLSVLSTQEKQCLATVFEKLAKQ------ ->tr|A0A239DQX7|A0A239DQX7_9RHOB DNA-binding transcriptional regulator, MarR family OS=Antarctobacter heliothermus GN=SAMN04488078_1011115 PE=4 SV=1 ------------------------------------AHAGITITQWRIIAVLGDTGRCTSAQLSRLTDMDKGLISRSVKSLAAERMITVTRDTSDNRALHLDLTAKGRATFEHTIPRMRSRQMGLRACLDEAEFDALMRACEKLEKA------ ->tr|D6XXH6|D6XXH6_BACIE Transcriptional regulator, MarR family OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN=Bsel_0497 PE=4 ----------------------ITLTAHLLQNEHNraLGDLDVTPAQSKALYLLNRFGSQSQTELQDRMYIKGSTMNGIIDSLQKKHLIHKEDSKTDRRVKVIWLTEEGERLEREIWEMLGALEARLMAGISPKRKQELIRTIEQLQDNLKT--- ->tr|U4KLC6|U4KLC6_ACHPJ Transcriptional regulator, MarR family OS=Acholeplasma palmae (strain ATCC 49389 / J233) GN=BN85410210 PE=4 SV=1 -----------------------------------NQKINLSNGQARVLRyiYENtkDDKEVFQKDILEAFSIRGASVNGLIEGLIKLDCIKREIDMSDKRKKKLKMTSNGNLIVLKSYEIILEFENSLKSSLQVEELEQLEKILLKLENEI----- ->tr|R9WI20|R9WI20_LACRE Transcriptional regulator, MarR family OS=Lactobacillus reuteri I5007 GN=LRI_0021 PE=4 SV=1 -----------------------------------APELDVTPQQAHTLFYIEKHAGLIQRELGDHFHLRNASVTSMVKNLERDGYIIRKADQESARIKRIFLTKKGEEKTNEVKEIFDQAYLQIIARLDERDINAIVKGMTNINNNL----- ->tr|C5QMM2|C5QMM2_9STAP Transcriptional regulator, MarR family OS=Staphylococcus caprae M23864:W1 GN=HMPREF0793_0478 PE=4 SV=1 -----------------------------------LDDFGITQEQSHTLGyiYRHQEEGMTQKTLLEAFDRKGSTVSSTLKILESKGLIYRKVNPKDTRSKLLKLTDEGITLVESFIKIFDEIEENMLKDFTDNDKEKLREYFDRMMNNL----- ->tr|A0A177XIV4|A0A177XIV4_9BACL MarR family transcriptional regulator OS=Brevibacillus sp. SKDU10 GN=AYJ08_17850 PE=4 SV=1 --------------------------------------EGITSAQYNVLELVQTQGPKTTNELASALGITVSGISKLTKKLLQKGLIEQQRSQADRRYYHIVLTEAGVDFLRKAEKSRKEIIQLIGKALSKEEIEAFSRICSKLNTYL----- ->tr|A0A1F9ZT83|A0A1F9ZT83_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_02805 PE=4 SV=1 ----------------------------------------LYPGQPRLLFFIDRQPGCTVSQLVEETGQTKEAISVSVKRLEEAGYLHKEINPMDKREKFLYLSEKGKTTADVIHNEFHRINEAMFEPLNEEEKEHLDEMFRKMSDRLHA--- ->tr|W1RZI9|W1RZI9_9SPHN MarR family transcriptional regulator OS=Sphingobium sp. C100 GN=C100_17990 PE=4 SV=1 ------------------------RFDQSVEQ------MGVSRAKFAVIALVSRKPGVSQRAIAERLQVTEVTAGRLVERLCADGFLERRGNPNNRRTYFVHLTAAAQPLLDELSVVAAAQEKQTFRGFSTDELDQLEQFLARISANIA---- ->tr|A0A1I9YEN4|A0A1I9YEN4_9BURK Uncharacterized protein OS=Paraburkholderia sprentiae WSM5005 GN=BJG93_04720 PE=4 SV=1 -----------------------------------TKCYNMTSIQFGALQVIADRPGIDQISLCQATDIDRTSIMRVLERLKSEDLITKEASTEDRRVSSISITEAGRERIDSLVARAEASQVRLLAPLTSGERQEFMRIMIKL--------- ->tr|A0A151Z0T5|A0A151Z0T5_9BACL Uncharacterized protein OS=Thermoactinomyces sp. AS95 GN=AYX07_02500 PE=4 SV=1 -----------------KQYAITRRIGQHITTALSEIGL--TRAQFHILNYIGSSDRCRATDIANMMEVKPSAVTLMIDRLEAHQWVRRSQDAFDRRVVVIELTEEGKNILSKAKKISEEVVKHYLSNLSQDDLIRLLEIYEKLERIVND--- ->tr|A0A0W8E7V8|A0A0W8E7V8_9ZZZZ Organic hydroperoxide resistance transcriptional regulator OS=hydrocarbon metagenome GN=ASZ90_017850 PE=4 SV=1 -----------------NMRAAMKKIDRLFSNKLEDIGI--SIPQSFILFCLQEENGLTLKEIGSRTLIDSSSMTVLVDKLEKDQLVKRQLDSQDRRAIRVFITEAGMEMGEKISVVISNLNTLLFDLLGEGNQKEFIHGLNNIVNGVED--- ->tr|C1ADG5|C1ADG5_GEMAT MarR family transcriptional regulator OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=GAU_350 -----------PTSSGPLVDVGelhrtLVNVLRLLRD--VDRESGVSPSRLSVLSVLVFVGPMSQAELARIEGVSAPSMSLLVRELETDGWVERTPDPVDARRTIVSASKGGRDLMLRSQRRRLDWLSAAISRLPVESQRVLAGCsthLDALIAALRETY- ->tr|A0A0P0Z6H2|A0A0P0Z6H2_9RHIZ MarR family transcriptional regulator OS=Aureimonas sp. AU22 PE=4 SV=1 -----------LTTPGHLVSLAARGFARLSEA--RLKPLGFGIGHLPVLVALRDGEASTQRELARFARIEQPPMAQMLRRMERDGLISRTPDPNDGRSQRVVLTDAALARLPQAITVLFQGNRDALEGFTDGEAEQFLNFLSRLLANLDGLT- ->tr|A0A1X2AZK6|A0A1X2AZK6_MYCPR MarR family transcriptional regulator OS=Mycobacterium peregrinum GN=AWC21_19760 PE=4 SV=1 -----------ESGAGYLVKRVQQSLRRNCDA--ALRSTGLSMAQYTALRALADHPQASAAELARLCFVTRQSLQDVLSGLRTEGLVEESPGPQRGRARALQLTAAGRRRLGQAHSAVIHVEQDMLNGLSGKEQKELATMLLRCAENLEAAA- ->tr|A0A1F3P1P7|A0A1F3P1P7_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_37_12 GN=A3G23_00480 PE=4 SV=1 -----------------------------------LKNHFVTDIHYNILRILRGQYPSALG-PTLIRQRmiRRAhQIPMqFFIALARKGWIKGIKVMQHGIQQEYVITKEGLELLDKIDPVTKEVEAKSMKNLTPVEAEQLSKLLDKLR-------- ->tr|A0A1R1M272|A0A1R1M272_9GAMM Uncharacterized protein OS=Motiliproteus sp. MSK22-1 GN=BGP75_12915 PE=4 SV=1 -----------------------------------LDPLDLTLQQLKILSIIYRSSENKAT-VNQIKQQmiDPSsNVSRLLNKLMDKGLIEKIRNREDQRVVHIHISKAGIRMMCTGKQAMDQGMS-VLGKLDLEELKQLDKLMNKLR-------- ->tr|Q11JD9|Q11JD9_CHESB Transcriptional regulator, MarR family OS=Chelativorans sp. (strain BNC1) GN=Meso_1089 PE=4 SV=1 -----------------------------------VGpASLITPVQAGVLILIAENPGVMQARLLKVLDVESATLVKSITRLAEFGYIERVRNPDDKRAFHLYLTPSGQEALKFVAAKMREREEGLRTSIDPAEYEVFRKVLLQLI-------- ->tr|A0A127MDI5|A0A127MDI5_9SPHN MarR family transcriptional regulator OS=Sphingorhabdus sp. M41 GN=AZE99_04750 PE=4 SV=1 -----------------------------------FSDLDLTQKQVSVLWLVDDHPDIAQTGLAKRMRMDRATTMAIINRLQKRGYLVRGKSKTDGRKQTLNLTDEGRTALASAKVAIQEHENWLKSRFKQKEVDLLIELLSKIH-------- ->tr|A0A1M4V417|A0A1M4V417_9GAMM DNA-binding transcriptional regulator, MarR family OS=Marinomonas polaris DSM 16579 GN=SAMN02745753_00553 PE=4 SV=1 -----------------------------------CSDLGISPGLFAIIAIVERNPGLTQTAVAQALGNDRSAMVAAVDKLEKMDILERRPAINDRRSYALFMTKKGEKFFLTLSERVMEHEQIMAARLEGDNELDwLLKTLDTLS-------- ->tr|A0A084K0B0|A0A084K0B0_9FLAO Transcriptional regulator OS=Nonlabens ulvanivorans GN=IL45_00810 PE=4 SV=1 ------------------------EMTESVSEIV--KKEGLTIQQFNVLRILRGRKGKAA-NLQDVSRKMIhsnSNTTRVIDKLISKDYVERKQCPSDRRQIELKITKKGLQVLENLDADIDARELSLINNLDEDQVKQVLEFLSK---------- ->tr|A0A1J0LLY0|A0A1J0LLY0_9FLAO Uncharacterized protein OS=Flavobacteriaceae bacterium UJ101 GN=UJ101_01754 PE=4 SV=1 ------------------------EIEQAIKKAL--KsSCGITHTQLNILSILEQEYPNPV-NSNFIKNNLIisssPDLTRLIDRLVKKELVERYTCPTNRREVNIVINPKGIETYKKAHKHAKQvTKNYFSEDLTEEEARTLYKILSK---------- ->tr|A0A1B9K957|A0A1B9K957_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G13_06475 PE=4 SV=1 ------------------------ALLENLNEIY--IKHQLDDKLFAVLLVVQWHHPEGV-KPSQISELTNfsrVQITRFVDALVANDLVARKQVPNDRRSHWLILTDKGSNFFQQQMPPLEKKVVAAWQVITAEERQQLRTILHK---------- ->tr|A0A1F1WYC0|A0A1F1WYC0_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC05H05 GN=HMPREF3151_11130 PE=4 SV=1 --------------------------------------RDTFSGQGRVLKLLALNNPVAQKELAYVLGIRSQSLAELLTKMEAKGLVSREPNPADRRTSIVSLTEDGQVAARELERSTDDEFDPFSTLSDTErteLDTILRKLIAGVEAEMSPS-- ->tr|A0A0F5PGR5|A0A0F5PGR5_9SPHN Uncharacterized protein OS=Sphingomonas sp. SRS2 GN=WP12_01960 PE=4 SV=1 ----------------------------------ALRPTGTDRARWRLLLTLWQGKPLSIKEIVEITNFNQSTVSKIIDRMKRDDWVNTESRRSDSRFTDISLTERGHQVLIELTKVASREYWRSLDGVSESDLQTTLNTLHKIMKNIAA--- ->tr|A0A1S2FNH4|A0A1S2FNH4_ACIBA MarR family transcriptional regulator (Fragment) OS=Acinetobacter baumannii GN=A7N09_34700 PE=4 SV=1 ----------------------------------SIKKLGIDNTRRKIILSTNALGEASITDIANLSTLKLTTATKAVYRLVEDGIVEVYSSTSDERISMVKLTAKGIELVEQINQISVVTLAGILNAFSEDELHNLNTQLKKLFDLMPS--- ->tr|A0A1B3M317|A0A1B3M317_9BURK Winged helix DNA-binding domain protein OS=Hydrogenophaga sp. RAC07 GN=BSY239_4416 PE=4 SV=1 ----------------------------------------MRTAEHEILMNLRRESGLSQQALAARCFTAKSHISHLLGEMASRGWVKRESDPADGRVKRLVLTPSGSRMAERTAAVQVDVVALMTAGATPDDLANVQAAMSEASRRL----- ->tr|V4PQP0|V4PQP0_9CAUL Uncharacterized protein OS=Asticcacaulis sp. AC460 GN=ABAC460_18095 PE=4 SV=1 -----------------------------------LRPMGINLTQMSLLNHFSWQPDraQSITELTDVMAINQPGVTKAIAALADRGLVEKIDDAEDARVKRVKITPAGLEALGQARQAAWPPVEAAFGSLDDEELAAFTSHLVKMKASL----- ->tr|N9PV99|N9PV99_9GAMM Uncharacterized protein OS=Acinetobacter sp. NIPH 2168 GN=F892_00818 PE=4 SV=1 -----------------------------------LSDYGLTPPQFTILKIVSVYSGCSNAEIARYASLTPQTVNLMINKLEKLEFVIKSAHPHNKKVQCIEITKDGLHILEQSSDAIEQLEAQLEHHFSSEEIYTLRKWFAFIQK------- ->tr|N8XMF2|N8XMF2_9GAMM Uncharacterized protein OS=Acinetobacter sp. CIP 56.2 GN=F966_03287 PE=4 SV=1 -----------------------------------LLELKVTSAQFAILSIIYNCPGLSNAEIARLSLLTPQTVNQIISKLESQNLLIKKKHPTNKKVQQLELTESGVECFHKCNVIIEDLEVEIKDQMPPDIESGVREWLKNIIEN------ ->tr|A0A0N0RD77|A0A0N0RD77_9CHLR Transcriptional regulator OS=Levilinea saccharolytica GN=ADN01_10040 PE=4 SV=1 -------------------QRAH-QMLRSARKIINeeLRPLNLSSAEGNILLHLFTQgqGELGQEQLVEQLDISKPAVSRALDSLEQKGYVLRQEDPSDRRVHRVRLTERARTVGPQIERAYNQLYAAAMQGISQEELAAFLHLFTRMSENFTRA-- ->tr|A0A087D9V7|A0A087D9V7_9BIFI Transcriptional regulator OS=Bifidobacterium saguini DSM 23967 GN=BISA_0706 PE=4 SV=1 -------------------DELHFLLLRAfnhSNRRIDeaIRRIGLLPGQPKIIECLAEQDGRTAKEICAECILDKSTMTGLLNRMEQRGLVRREVHETDKRSYRVFLTESGLDYATRIAAIMQQADELAMQGMSETERKTLREGLRHVIANIEQE-- ->tr|F4GQ51|F4GQ51_PUSST MarR family transcriptional regulator OS=Pusillimonas sp. (strain T7-7) GN=PT7_0834 PE=4 SV=1 -----------------------------------LDNWSITPPRFSAMIIIDKNADMKLTELAAAMGIARSGAVEVVNSLEKLGFVSRTDSTVDKRAHALALSSEGKKALSSITQAIQAHDARISTRLTADEQAELRRLLGLLG-------- ->tr|R5ZBP3|R5ZBP3_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:536 GN=BN700_00482 PE=4 SV=1 ----------------------------------------------------------TPKHIYELQMFTRGHISQSMKRLGKAGYLRMEVDKHDHRVFHCFVTEYASEILAQVDEAMESIHRKLFRQISPEQMTQFLEIAQVINRNIIEE-- ->tr|K2EV21|K2EV21_9ZZZZ Transcriptional regulator OS=groundwater metagenome GN=marR PE=4 SV=1 -------------------------------------EdNATTLLQIEALKYIHANSSVTVGSLARELDMSLSSTTQLTNRLADKGWVSREIDQNDRRVTGLSLTKLGLTQIKGLINPMISSNYKVLASIPEKDLKEMIRIFGNIADSQR---- ->tr|A0A1Q3Y4U2|A0A1Q3Y4U2_9BURK Uncharacterized protein OS=Burkholderiales bacterium 67-32 GN=BGO71_31155 PE=4 SV=1 ------------------LHRAAHIIAATFGDELKADDIPL--SVWRVLATLNDRDHQSLSELASHTGAELSYLSRTVAQAEERGFVVRSAQPGDKRATSVRVTPAGRAVVRKFSPLTQTLQKQWLADIPDADVEATFRTLRAVYQNAV---- ->tr|A0A1W1WDD3|A0A1W1WDD3_SULTA DNA-binding transcriptional regulator, MarR family OS=Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1) -----------------------------------RTEYGLSLAQIRCLFQLRS-GDQTAGELAKSLGIRATSLTRMIERLETENWVKRQNDKHDRRRIVLTLTEEAEDMLSHLDFFLDSPAAMGIKRMTPQERVEFTQALQRFLQHV----- ->tr|H8L1H4|H8L1H4_FRAAD Homoprotocatechuate degradation operon regulator, HpaR OS=Frateuria aurantia (strain ATCC 33424 / DSM 6220 / NBRC 3245 / NCIMB ----------------------------------IVAEQGLTEQQWRIIRIMLDTGPIEPYQLVSLCSISSPSLTGILGRMEQQELVKRHKMGHDHRRRLIRLTDRGQALAETIVPRINEAYRQLESRLGEPLIASLVQTLEAVNARL----- ->tr|S3BF30|S3BF30_9BURK Uncharacterized protein OS=Sutterella wadsworthensis HGA0223 GN=HMPREF1476_01317 PE=4 SV=1 ------------------AARMHEEGRRFLLTEMKKAGLDeLTTSCGDIFQVLFQ-qEGLSLTAVAQKIRRTKSTTCVMLDRLAKQGYVDRLPSESDGRASIIMLTEKGRALKPIMADISTRMNERILGSLTEDEADQLEVLLAKAVRTY----- ->tr|H1PPN2|H1PPN2_9FUSO Uncharacterized protein OS=Fusobacterium ulcerans 12-1B GN=HMPREF0402_00375 PE=4 SV=1 ------------------LSRAHHRSRIFMDEELRKKGITdLGYSHIRIMIVLYV-fKTLSMKEITEKISKDKSTVTILVNKLEKKGYVRKRVCSKDRRVMHLELGERAEEVIGVIFDVSEIFHRKVEQILEKDEINTLKRIMSKLLEKW----- ->tr|U2Q7W0|U2Q7W0_9CLOT MarR family transcriptional regulator OS=Clostridium intestinale URNW GN=CINTURNW_0223 PE=4 SV=1 ------------------FSKFLDKYNNSIEKKLKEENFIgLGASHFAILIGIiFSKeKRLCMKEIASFINKDKSTVTQLVNKLIRYDLIEKKYSESDKRMCYMMLSNKGRENEALFIKIYNESEA-ENNMITVEERQSIENIVKKLIISM----- ->tr|A0A1L8N243|A0A1L8N243_9SPIO Uncharacterized protein OS=Treponema sp. CETP13 GN=BKP49_04040 PE=4 SV=1 ------------------ISRIDSLTSVYLKNKLEKQGISgIVSSHGFILHLLTLHKKLTMGEISKLINRDKSTTTALIKKLEQGGFLRKVTCKSDSRVRYIMLTPAGLKLTATTADISKELINTAYKNFSDSEKTELYTLLLKLEENF----- ->tr|A0A162BDH7|A0A162BDH7_9GAMM Uncharacterized protein OS=Marinomonas sp. TW1 GN=OA79_11925 PE=4 SV=1 -------------------------------HLAAEADILIPVTHIRAIKCITNIENCSARDIAKRLRLDKSQVARLVKDLLEQDYIEKDKHPTNNRCQVISLTAAGKGLQQKIAHVDNQARTQMCSGMTQQEIESFIQLTELMKSNLTQ--- ->tr|R6ELJ9|R6ELJ9_9FIRM Transcriptional regulator MarR family OS=Ruminococcus sp. CAG:563 GN=BN710_01010 PE=4 SV=1 ------------------VHNELRSLSHLIYRFIENLpnkekIDSMTGTNACIIGYLTENADHDvfQKDIekAFGITR--STASKVINLMEQKGLVERHSVSCDARLKKIVMTDKSKAISHLMAEDMDLVESVLTDGFSSDEKEAMCDYIKRMKRNLKNY-- ->tr|R5HCW5|R5HCW5_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:114 GN=BN469_00927 PE=4 SV=1 ------------------QVTQLACIVNQLHRMAMRMppdvlPSGMTISQLSTIGFLYFSQQGDvyQKDIesFFKLRR--STVSSQLDTLEKKGLIQRVPVSHDARLKKLVLTEEGLRISGQVLLVLEQMNDFMIQGLSQEETVVLTNLLRKIEQNLSRI-- ->tr|A0A0T2YG83|A0A0T2YG83_9BURK Uncharacterized protein OS=Hydrogenophaga sp. Root209 GN=ASE11_14190 PE=4 SV=1 ---AKTEVLDHLHTLMHGLRR-------HLQEAARQDGDGLGPMEVRCLGYFLRHAGATQRDLVQHSGRDKAQIARIVKALHERGLLQSQPDPNDGRSQRVSVTPEGQALQRKMQLHRVRFEKSMTAGLSESERATLLALLGRLQENVGE--- ->tr|A0A1B9YJX9|A0A1B9YJX9_9BRAD Uncharacterized protein OS=Bradyrhizobium sp. LMTR 3 GN=LMTR3_09695 PE=4 SV=1 ---MDDELLDLFGAVANGLHA-------RLQGLTVLDELGLAPFQARTLSLIARYPGCSQQALSTSTGRDKAQVARAIKELETRGLITRQAHRRDWRAQSLSVTLEGKQASKLLLRHRAQAGADMLQDLNLKEREVLRCALSKMRARLGA--- ->tr|A0A1M7NRS2|A0A1M7NRS2_9BURK DNA-binding transcriptional regulator, MarR family OS=Duganella sacchari GN=SAMN05192549_104136 PE=4 SV=1 ---QSEQVFDAIHSIMHLYRA-------RQLRGLRDTPHEITHMEYKALGFFSRHPGATQGDLAAHSGRDKAQLARLLKGLRDKELLDAAADQADRRITRLTLSAQGQKIFNSLNQLGTQASSAAVDGMSAAQLTQLQALLQQIRDNLEA--- ->tr|A0A1L8MM34|A0A1L8MM34_9STRE MarR family transcriptional regulator OS=Streptococcus sp. NZ1587 GN=A9Q68_07370 PE=4 SV=1 ----------------------------------------------------------------------KSVASNLVKRMEKNGFIEVFPSQTDKRYKQVIMTQKGEDKLPLLQECRKDIENYFFKEITHEEFQVVRKVIDQLKQNMLD--- ->tr|A0A099CRU0|A0A099CRU0_9GAMM MarR family transcriptional regulator OS=Oleiagrimonas soli GN=LF63_0114275 PE=4 SV=1 -------------------------------AALQEEGVDLRFTQFLALKRLALDGPMCAGELARAVDHDAGAMTRVIDQLETKGYVRRQPHEQDRRSLRIAVTDAGMATWQHMAKAHERTLERAQQALSPAERVQLMDSLERVLAALR---- ->tr|F2IE50|F2IE50_FLUTR Regulatory protein MarR OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_0360 PE=4 SV=1 -----------------------------------MEKTPVERYYFPLYL-IGKKNGiISQQELANQLLMDKVSLVRILDALESDGFIERKTNPNDRRQHLLNITSQAE----PWIGEIEKGiketNEYFFSLLDPSLHATFELILTELITKTQE--- ->tr|A0A143YYB4|A0A143YYB4_9LACT Helix turn helix multiple antibiotic resistance protein OS=Trichococcus sp. ES5 GN=TES5_1778 PE=4 SV=1 --------------LLISLSKLSKVYRAEVKVE--MSASDFSPNELDLITFLSNNEMDTSKEIADFLGLSKSLIARSVDSLVAKGYLETNVDEGDRRYIHLVLTDRAKPIADRLRNIRKQFIASMTEGINQEQFTQFEATLEKMVANVERK-- ->tr|B9Y429|B9Y429_9FIRM Transcriptional regulator, MarR family OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00560 PE=4 SV=1 --------------MLKGYARLREAYSRFCAHS--AAGEAFSPNEMNVLIFLSNNPsINTAKELTVTLGVSKGLVCRSVDALVRRGYLTSEEDAKDHRILHLRLTQKAAPVIGQMRVSMDHFSQTVTRGISEEELAVYTRVQHQIYANIEAM-- ->tr|T0T767|T0T767_9DELT MarR family protein OS=Bacteriovorax sp. DB6_IX GN=M901_0279 PE=4 SV=1 --------------IPLSMGLMKSYIRKVCE-------AEFSFSKFRIIALTQS--gKSTVSEIAEMMHISRPAVSKLVESLVTDKYLLRHTDEEDRRVIHLTATTKGKKKFQKVRHLASQMFIENLEGLNPLEIKELSQALSILENFVLQA-- ->tr|R5KH73|R5KH73_9CLOT Transcriptional regulator MarR family OS=Clostridium sp. CAG:264 GN=BN572_01559 PE=4 SV=1 --------------IFDMTKSLMKLQEKYLESI--RIDYKLSRIEVIIITFLHNNPvHDTARDIVEFRMLQRGNVSTAIDSLADKGYLTRHPDTNDKRIIHLKLSDRSIPVVHAIEKKQDELISCIFEGFSDDEKKNFASYNKRLYDNVLSH-- ->tr|F4GH30|F4GH30_SPHCD Regulatory protein MarR OS=Sphaerochaeta coccoides (strain ATCC BAA-1237 / DSM 17374 / SPN1) GN=Spico_0275 PE=4 SV=1 --------------FYLYAKLIKRMYESALTKA--AATIKLTLPEADVLCFLRENPeFDTARDVALYRDVSRPYVSKAVELLVNKGYLIVSGDKDDRRLQHLTITERGKPAAEVLHKAQYAFYDSVTAKLTQEETSMLLTLIGKCAETLNP--- ->tr|A0A127EFK8|A0A127EFK8_CLOPF MarR family transcriptional regulator OS=Clostridium perfringens GN=BXT94_03155 PE=4 SV=1 --------------FLVSFTKAKKTYKKFISPT--LNDLGLTHNEFEILVFLQENLeYNTAKDIVEFSGLSKGLISRSIESLLKKEMLSIKKDDKDKRIFRLYISPSANETLNILNKVSNRFFKLLLEDLKDEELIFFDEVLNKMIKNLNNL-- ->tr|A0A1A0RKH0|A0A1A0RKH0_9MYCO MarR family transcriptional regulator OS=Mycobacterium sp. 852002-51961_SCH5331710 GN=A5752_20865 PE=4 SV=1 -----------------------------------LEPFGVEPRTYAVLKALSEADGQTQRQLSVQLNIHRNVMVTVIDKLENQGLVKRMPHPGDRRAFAVTLTGKARELLPKLDEQGRKQEAEITAPFTAAERKTVLRDLQRMSAA------ ->tr|C5T920|C5T920_ACIDE Transcriptional regulator, MarR family OS=Acidovorax delafieldii 2AN GN=AcdelDRAFT_3400 PE=4 SV=1 ------------------------------------DAQGLTTQQWAVLGALSRpeaADGMSVGDLARYLMVSRQNLSGLISRMERDGHLGSAPDGRDRRSRRITMTDSGRGVWVNeAQPNIRRYYGQVLADFSVGDMAHTLHYLLKLLDNMQRL-- ->tr|R6M4Y3|R6M4Y3_9FIRM Uncharacterized protein OS=Megamonas funiformis CAG:377 GN=BN632_00317 PE=4 SV=1 ----------------------------------NLVSLGVTVQQALVIAYLDKSKDKkvTQRMIEIGLNNTNPTVTNIIKSMMSKNLIYKIQDKVDKRKYYLYLTPLGLSIASECAKRMEATDIAAYKNLTEEELKTLRVLLEKVEF------- ->tr|A0A1L8REI4|A0A1L8REI4_9ENTE Uncharacterized protein OS=Enterococcus canis GN=RU97_GL002259 PE=4 SV=1 ----------------------------------QLKSFDLTFSQFRILIYLHE-QLEptSMKAVEREFSLTQQTVAGLVKRLESKGFLYTKESPTDKRAKEIRLTEKGEASYQEAAGAYYQAQTSLTKGLSAAEEMELQRMLKILLNNMS---- ->tr|W6WZ06|W6WZ06_9BURK Transcriptional regulator, MarR family OS=Burkholderia sp. BT03 GN=PMI06_003285 PE=4 SV=1 -----------RGRTVPWMARTVHRLyDAQAQKILDRENL--PIAYWYYLRVLAARGEINQLELSKRVGIASTTAVPALDNLEKRGLVQRTRDPNDRRKYFVSLKDDGKRLVDEMMPELIDMISASLDGITQRDMRVFWKVMHQIENNLNQASQ ->tr|A0A1V4ENY1|A0A1V4ENY1_9ACTN Uncharacterized protein OS=Microbispora sp. GKU 823 GN=B1L11_00020 PE=4 SV=1 -----------LATSVCWLLGDAARElTQELERVLRKDDL--RWRDYGVLVVLEAAGPLSQQEIGRRLSVDRSTMVHVIDVLEERGLVARARDAADRRAYSIRLTDSGRALLVDVLhPATEAVQERVLGGLAAEDRMHLNRVLAQLAAGR----- ->tr|R7F1R0|R7F1R0_9BACI Uncharacterized protein OS=Bacillus sp. CAG:988 GN=BN822_01037 PE=4 SV=1 ---------------LYLTKRAHPFFESRMGAITNQIG--LTPQEGHILLFLAN---NPDCNHAcdavVYRGLSKSYVSKALTSLSKKGLIVFQEDTSDHRYQKIVFTETAQEKVKVLQEGQKALFKELIQGLSKEDLDVCKKVLNQIFQNFIKL-- ->tr|E2NU45|E2NU45_9FIRM Transcriptional regulator, MarR family OS=Catenibacterium mitsuokai DSM 15897 GN=CATMIT_02120 PE=4 SV=1 ---------------WDQHKTITLYYEMLTASTCDKYN--LKKMEYDILMFLYH---NPEYNTAadivRIRKSTKSHVSTALKVLEDRGYITKKTNENNKKRVELFLEDSANEIVKEGLNVQNQFAHDMLQGLTQDEIKVCKKVFEKICRNAEEC-- ->tr|R7HVX4|R7HVX4_9CLOT Transcriptional regulator MarR family OS=Clostridium sp. CAG:411 GN=BN648_01666 PE=4 SV=1 ---------------VQPSVLIKKLLEKKIAPIMKEYD--LRIVELDILFFLSK---DEHLDTAkeimQKKHLSKAHISKSIDNLKKRNLIRISEDAQDHRILHIALDESAYKVVDKVMKVYTECLQTIHKGITEEEWETVHRVLHKMLQNIEEA-- ->tr|A0A1C6E7S8|A0A1C6E7S8_9FIRM Transcriptional repressor MprA OS=uncultured Oscillibacter sp. GN=SAMEA3545356_00076 PE=4 SV=1 ---------------LRVIQQFRRYYDRHFSELLSRTG--LSMREIHVVLFLAN---HPAHDTArdvtELRGLAKSQVSAAVDLLAARELLRRQPDKADRRVIHLALTDAGAALAREGQKLQSTCLDALFAGLTQSEAERFQELLEKVLTSAEVR-- ->tr|A0A1C6GPP6|A0A1C6GPP6_9CLOT Transcriptional regulator SlyA OS=uncultured Butyricicoccus sp. GN=SAMEA3545389_02071 PE=4 SV=1 ---------------AADAFHAGQLYRSCFRELTESCG--FTPNEMFVLLFLYRN--APEQDTAtviaQAWNVSKPLVTRSVDGLQKRGLLYCVRDENDRRLVHLHLSDEGHAAAKTLHHRCETFALTLQQGISEQEMQTLCSVMQKMQRNLNDL-- ->tr|A0A1C5NVQ6|A0A1C5NVQ6_9FIRM Transcriptional regulator SlyA OS=uncultured Blautia sp. GN=SAMEA3545264_00164 PE=4 SV=1 ---------------LISGNAYKRVYEKRLEGLKSKYG--LKRIDLDILYFLCR---YRQRNTSkeitEQNQYTKGHVSQSIERLVKKGLVRTMPDEADRRCLRIIPEESAEAVYAKMHQVREQMFGDIFRGISQKDIGAFERVSQKVYENMHEE-- ->tr|A0A1C5UL37|A0A1C5UL37_9CLOT Transcriptional regulator SlyA OS=uncultured Clostridium sp. GN=SAMEA2393091_03095 PE=4 SV=1 ---------------LFMIHNSLELYENLCQPVCRECG--IAQTALDILMFLAN---NPEYYTArdicRVRGIKANLVSFHVEKLVQEGYLEREAIPGDRRQVRLLLTGKSQRVIEQGRSVQQRYREILVSNIAPSDFETFQRCMDTIRQNIERA-- ->tr|A0A1C5QG60|A0A1C5QG60_9CLOT Salmolysin OS=uncultured Clostridium sp. GN=slyA PE=4 SV=1 ---------------VFWNMHFKELFQLVYAQYGEIHH--LTETEIQILLFLRD---DSVYNTArdicKMRGIAKSNVSNGIRMLERKGYVSIRIDEENRKIHRLSLTEKSRPIAAELWQIYEDCQMRILDGITKEEVKAVYGFFEKCDVNVVKE-- ->tr|A0A1H6GBT6|A0A1H6GBT6_9GAMM Transcriptional regulator, MarR family (Fragment) OS=methanotrophic bacterial endosymbiont of Bathymodiolus sp. GN=METH_1349140 ---------------LKLIERISTLLRAEQRKKYSSLG--LQPVHVQTLDYLANC--NRFSDTPaavtDYLGLTKGTVSQTLQVLERKGYLEKIQDLVDKRIVHLKILPLGQQLLKSITPFD---------VFTKAEQAIANKQFDSISAALYEA-- ->tr|A0A1Q6LYV6|A0A1Q6LYV6_9CLOT Uncharacterized protein OS=Clostridium sp. 44_14 GN=BHW06_03790 PE=4 SV=1 ---------------LLSGQYFKKYQEAMYSEITEKFN--MTLMEVRVLLFFDN---HGSSNTAkdlvRIFHYTKSNVSKAIDSLLLRGYLKKQYDDQDRRYIHLTVQPEAADVLEMARQCQKDMFQSVFRGISEEELQIVQKVAQKIHQNISEA-- ->tr|A0A1M4SXU9|A0A1M4SXU9_9CLOT Winged helix DNA-binding domain-containing protein OS=Lactonifactor longoviformis DSM 17459 GN=SAMN02745158_00317 PE=4 SV=1 ---------------WLLIASLKKEYFNRKKTVISRFQ--ISSAELDILLFLAN---NKRFDTSadivRLRKMQKSHVSLAVKELTQKGYLTCEMNSFNHKKLHLKLTEASKEIVQAGQTMQREYLEFIFAGFSKEERLHVLEFCSKIETNLHGK-- ->tr|A0A1Y4SJZ3|A0A1Y4SJZ3_9FIRM MarR family transcriptional regulator OS=Massiliomicrobiota sp. An134 GN=B5E79_08030 PE=4 SV=1 ---------------LGMHPYIIKKYNSLFDELLKEYQ--MTQVEIDVLAFLAN---NPEYNHAqdivNVRGISKGHVSLAIEKLVKRGLVTRNPDPVNRRWNILCVEKKAGELVKKIQNIQHAFDEQAYQNISQEDIVKYHEILQQVYHNLGGG-- ->tr|A0A136MZQ4|A0A136MZQ4_9BACT MarR family transcriptional regulator OS=Bacteroidetes bacterium OLB9 GN=UZ09_BCD002000897 PE=4 SV=1 ----------------------AKLMKLIlSRNLLSSPEIDLTVDQWVIMHLIDEHKTLSQQQLGELALKDAPTITRMLDLMETRKLIVRAPDKSDKRKFQIRLTSIGKEKYLTATPIIHSFRSDAYKGLTREELMHLENM------------- ->tr|I2F5Z8|I2F5Z8_9BACT Transcriptional regulator OS=Mesotoga prima MesG1.Ag.4.2 GN=Theba_1691 PE=4 SV=1 ----------------------------------ALEPHGITYPQFGALLVLSSRGEMTQKQLSSHLETDTTNTMVICVGLEKKQLITREQSSEDKRANIVSITAKGREIFQKSMAVLRESYGPTANSISEKKRDTVNSVLDKLLESLN---- ->tr|A0A0V8T5K4|A0A0V8T5K4_PSESD Transcriptional regulator OS=Pseudomonas sp. (strain ADP) GN=AOX63_30100 PE=4 SV=1 --PPQDHLFALTGSLQPARRAWQQAASLVLAES----GLSL-AVATPVLLVSRMGDGVLQNVLADCIGVHPAALVRTLDQAEAAGLLERRMVPGNRRLRAIHLQDAGRELAERLEKALNALRAEVLGSIPREDVETATRVLRLMEEKAR---- ->tr|A0A087NBJ0|A0A087NBJ0_9SPHN MarR-family transcriptional regulator OS=Sphingobium sp. ba1 GN=IL54_1910 PE=4 SV=1 --ADAEQELALLHLLAPVARGWRQMGDAALAQF----GVSS-SAGWCLMHLDQLEEPPRQAELALLLDISPPSLVRTLDQLQIAGWIERIADPDDKRSNRLALTEAGKALAEKIAARLAEVREGLLGGLPDGAVEVGVELLGLLSLRMA---- ->tr|F0RPZ9|F0RPZ9_DEIPM Regulatory protein MarR OS=Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VK -----TKYSEVSEEAVVSLMRTYAVVMADFDQFVRQFG--ITPAQYNILRILSGAEraGeqLGRNEIRRRLIDRvSPDVSRMLTRLEKAGLVSRDRrrrEGEDQRLVPVQITAQGLELLARVEGPLAERNMHSMAALTTAEQLQLIGLLERIRKGIRAL-- ->tr|I0II53|I0II53_PHYMF MarR family transcriptional regulator OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_27820 P -----GPFDFVQQELYLNLVRTASIAAEPVQRCLKAHG--LREPAFNVLRIVAGRGaeGLPSQAIGAHTVSRVPDITRLVDGLEKRGLVERRRCPHDRRVVHVVITAAGRRKAERASRDVDAVHRSQFPGLTEPRIARLIRLLERARERDAGE-- ->tr|A0A117UQN4|A0A117UQN4_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium RA GN=AWN76_10440 PE=4 SV=1 -----SAIDQRELEAFTRALRR---IGVVFMRIAGQHS--TahetySKQELLALGVLRVSGpcR--MGEVAEHLGVGQSAVTPLVDRLEAQGLVRRRRSDEDRRVWLVALTEKGEAVVAEEDQVYQHVATEMLAPLSASERATLIALLERVGAAVPEG-- ->tr|A0A1H1M556|A0A1H1M556_9MICO DNA-binding transcriptional regulator, MarR family OS=Brevibacterium sandarakinum GN=SAMN04489751_0547 PE=4 SV=1 -----WNDSTDGMTTVISVMRVHQLFLAKVDAALKPFA--LTFSRYEVLTLLSFTKsgTLPMSKISARLQVHATSTTNSVDRLEKAGLVKRRSHPDDRRTTLVELTDTGRALSSRATAALNDEVFS-SPALAGADLGGLLPHLESLRSELEGR-- ->tr|A0A1Q3H413|A0A1Q3H413_9BACT MarR family transcriptional regulator OS=marine bacterium AO1-C GN=BKI52_04610 PE=4 SV=1 -----RTFPDSKHKLVVNLTHTSNWIKNRYTEFLKSYD--ISTQQMNILRISRAEGdWSPMNTVKELMIEKAPNATRIADKLVTKGLIERSRSQEDRRVVFIKITQKGLDLLKEFDIAHEKSLFRFTDNITDKEAELVSNILDRLRE------- ->tr|A0A1T5JZJ0|A0A1T5JZJ0_9CLOT MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor OS=Maledivibacter halophilus GN=SAMN0219 -----NWIGEIANKTIIELQKTAGILEEIHNTFFNQFD--ISSTKFNLLVILYNSSqdGITLSEIGEEMLVTKANITGLVDRLEKQGYVSRKRHSQDRRKVIAAITKQGRKFTEKVIREYKIWSKDVMTILNDEEKKQLLNLFNKLQRGLVSK-- ->tr|A0A1V1U8S5|A0A1V1U8S5_9FIRM MarR family transcriptional regulator OS=Carboxydocella sp. ULO1 GN=ULO1_19990 PE=4 SV=1 -----EKRTVQAEEINLLLKSIIGHFRKFVSNHIKDLG--LTVPQLLLLRVLYQQPeqT--LSELCQQLGLAKSTVSDLVDRLEKQELVVKRRGEQDRRTVRISLAEKTMALGETIQAIKTDYWSALLSQLTPAEVEEILRALRKLQGLISAS-- ->tr|D4H6T8|D4H6T8_DENA2 Transcriptional regulator, MarR family OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_1028 PE=4 SV=1 ------------------------------------NEAGVTFSQFEVLVVVYHFAPMTVNSIIENTLSTIGNISLVVTNLIKDGFLKSEVHESDKRSKLITLTQKGEEFMDDFFPTHLRNIENIFSVYTQEEKELLLSLMRKLYRD------ ->tr|U3VDL9|U3VDL9_CLODI Transcriptional regulator, MarR family OS=Peptoclostridium difficile E10 GN=BN166_2230027 PE=4 SV=1 -------------ELLKWVSI----INRYNTNYIdrKLADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVKDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLA----- ->tr|A0A0R1GWB3|A0A0R1GWB3_9LACO Transcriptional regulator OS=Lactobacillus parabrevis ATCC 53295 GN=FD07_GL002101 PE=4 SV=1 -------------DIVKWLSI----ANRYTRIALdrRLQPYRLNASMYYYILRLHEQPRLTQDKLISLTYLNPSNVTRAVNQLVNLGYVRKRQSKLDRRVYELSLTKRGERLYPEIVKIRQEVANSLLTEIPAADHDALVDQIRQLALTA----- ->tr|F8HY14|F8HY14_WEIKK Transcriptional regulator OS=Weissella koreensis (strain KACC 15510) GN=WKK_00570 PE=4 SV=1 -------------DQLQSFGI----VSRVIRTELnrVLKPYGLNDSNYFFISYIADHPESSQGDLTRTMFLDHSTITRSVAKLVELGYLEKHLDEKDHRTTRLFLTNKGAEIRYEIHELTTTIFDNTFSEISSEESETIKSILLKTANHL----- ->tr|A0A0R2EZ79|A0A0R2EZ79_9LACO Uncharacterized protein OS=Lactobacillus camelliae DSM 22697 = JCM 13995 GN=FC75_GL002344 PE=4 SV=1 -------------TIMKQLHV----ASNIALRVLerRLKPLGVNSSQYFFVLKLHDDPGVTQDQLVREDSRHQSNVNREISRLVDLGFVDKRQSTTDGRRYQLWLTEAGEDLYPKVKAALDAQEKVLSECLTAadgrVTQADFLAVLHRITQLD----- ->tr|A0A1Z5J505|A0A1Z5J505_9LACO MarR family transcriptional regulator OS=Lactobacillus silagincola GN=marR_20 PE=4 SV=1 -------------DFVQQVAV----LNLVITNHIteMLAPYEVNASNYFYVMKISENPGITRSDFNQLVHLNHSSITRAVNHLIEKGLIKQSINPRDKRGTQLFLTDKGIQLNREITQKISELNANLMAKLEPQQQTIFSNIVK-LRQSI----- ->tr|A0A1K1PR94|A0A1K1PR94_9FLAO DNA-binding transcriptional regulator, MarR family OS=Sinomicrobium oceani GN=SAMN02927921_01955 PE=4 SV=1 ---------------------------------------------SQVIFLVKEQGKTTATAINKVLQLDEGYLSRIIKKLISDSLLIKEQSQTDKRCFEIMLSPKGIEEQRKMDKLSSESVRAIISHLSETEQQELAGSFQRIMALL----- ->tr|A0A1H6BYL1|A0A1H6BYL1_9GAMM DNA-binding transcriptional regulator, MarR family OS=Marinobacterium lutimaris GN=SAMN05444390_10315 PE=4 SV=1 -----------------------------IAAFKSFEGVTtgygsIPRYY-GLLELLSNNPGVTHNRLAEAVYLDKSSLVSILDMLQKEGVIKREPSDTDRRVKNLFITPKGAELLNDLNRHVTEHESMLMAGFSDEERSTLVNMLDKIDNNIR---- ->tr|A0A1C6IT89|A0A1C6IT89_9CLOT MarR family OS=uncultured Butyricicoccus sp. GN=SAMEA3545389_02699 PE=4 SV=1 ----------------------------------DLKSMGLAAEQADTLLFFHAHSGSSASDLRCSLGVTHQAARALVQRMADKGLLCVTPSPRDARYKLIALTAEGEELYETMQRNCTNFGDRLLEHIPADDREKLLAMISQALDNMEK--- ->tr|A0A1Z5IXQ4|A0A1Z5IXQ4_9LACO MarR family transcriptional regulator OS=Lactobacillus pentosiphilus GN=marR_13 PE=4 SV=1 ----------------------------------HIRDLHITTDQADALIYYHDFPDQTISDLKNFQHIRHQSAQVITQKLVDKGLVTLIKNPNDRRAKLVVLTDAGNMMRLHLKNNGSRTGEQLLNGFSDNEKQQFLTLLEKSISNLNR--- ->tr|M9R961|M9R961_9RHOB Transcriptional regulator OS=Octadecabacter antarcticus 307 GN=OAN307_c37350 PE=4 SV=1 ---------------PVSIGRQLNITASVGNAVCNqlLEPHDLTLAQWAVLSSLWQNGDMSLKDLAKLTGNAPPATSRIVERMVMGGLLLRTQNNKDRRAVSVSLSPKAEG-FRYLHTIYEDVNAVLLADLTASEQAQLFKLLRKVEENARNWV- ->tr|A0A1F4EIZ7|A0A1F4EIZ7_9BURK Uncharacterized protein OS=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960 GN=A2710_07150 PE=4 SV=1 --------------------------------------FGMGVNEWRVLSYVELFPWSTGTQMCDLMGVDKSAVSRGCAVLMEHGLIVSRPRGLRKIEY--GITPKGKVAFQQFLRVSVARQEALLTGFSNTERKLLISFMHRLLDNLPLA-- ->tr|A0A1T5GWH0|A0A1T5GWH0_9SPHN DNA-binding transcriptional regulator, MarR family OS=Sphingomonas histidinilytica GN=SAMN06295920_12226 PE=4 SV=1 --------------------------------------FGLGILEFRLLVMLAAEPDIPPSRICEVMGLDGGAVSRALRGMEARGLVVSRPDRRNPAYKLWSLTAEGARLQDEAVLVSMERDAILLADFTDAERSELIAMLRRMLARVDRL-- ->tr|A0A1R1FU34|A0A1R1FU34_9BACL MarR family transcriptional regulator OS=Paenibacillus sp. FSL R7-0337 GN=BK147_33320 PE=4 SV=1 -----HSIKTIELEMAVLFRRLTSItTFK--------KIGNLDRAAYLLLHHIeSREGTAGIKAISDEFQLDISTVSRQAASLESKGHITRVPDPVDGRAYSLQITETGKASLEENRRVRQEMIEQLLKGWSEEEGHLFGELLQKFNAAF----- ->tr|A0A1M4X0I0|A0A1M4X0I0_9BACL DNA-binding transcriptional regulator, MarR family OS=Seinonella peptonophila GN=SAMN05444392_10463 PE=4 SV=1 ----SENLNQIDHEIVMLMLRADFKkaLDR--------NKESLERSSYLILKELMESRVRGLSELAEHFQLDLSTISRQIRILEKNNYIRRFVHPQDARIKLIEITKNGIEVLQKTQKKRLKAYHELTHDWTSEEVTMFAQLLTRLNRAM----- ->tr|A0A1V4Q446|A0A1V4Q446_9ACTN Transcriptional regulator OS=Gordonia sp. i37 GN=B1964_18935 PE=4 SV=1 ----DRDIDQLFDTLARYVRIRDRAvhTtfRT--------PDGEFETAAFKGLFHL-AKRPMRSRELAAELGADPSTVSRHVSQLVDLGLIRREADPHDGRATLLVVTDAGRDRVESMRAGRRSAVNSAMSEWSADEMATLVTLLTRFVDAA----- ->tr|A0A1M6F776|A0A1M6F776_9DELT Transcriptional regulator, MarR family OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_00740 PE=4 SV=1 -----------------------------LQNAFAENEIAVSPMQARILFALKGRSPRTMTQLSKALSTDNAAITRLVEKLVKMGVVERKNSPHDRRAYLIEITPRGNEEIAKAEAVMHLVNEEFSALFTPDQKAVLQGFLSEIE-------- ->tr|A0A150YC03|A0A150YC03_9FIRM Uncharacterized protein OS=Ruminococcus sp. DSM 100440 GN=AXF09_02615 PE=4 SV=1 ------------------------------RPYFQEIGLTVGQGQPRILNSLRKYGTMTQRELADCCFVDVTTISRTVDRLVAAGLLSKQIDPECRRSCLISLTEEGRKKAVQVQHIFEKGDEIWWKSFDEEELERLYQYLLKMEQSLKGD-- ->tr|A0A1Q3YNA1|A0A1Q3YNA1_9BURK Uncharacterized protein OS=Burkholderiales bacterium 70-64 GN=BGO72_20985 PE=4 SV=1 -----------------------------------LTRSGVTIAQWRVYMCLLTHGPSHLNGIVAFTHLPQSSLSRSIAAMHDRGLVRNARNATDRRIARIEITPKGRRHLAALTEKIDAACADAF-RLSPAEEVRLIRRLDVLIARLSD--- ->tr|A0A0C2DJH5|A0A0C2DJH5_9STAP MarR family transcriptional regulator OS=Salinicoccus roseus GN=SN16_11660 PE=4 SV=1 -----------------------------------LKKYELSPLQFVALQWVDDKEGITIGELSNRLDLAHSTTTDIVDKLENGAFVKRQKYEKDKRIVLVLMQDKGHQIIKEVIAKRISYISEITSHLSADEKEMLPVILESILQESE---- ->tr|M1ZGD3|M1ZGD3_9FIRM Putative Uncharacterized HTH-type transcriptional regulator YsmB OS=[Clostridium] ultunense Esp GN=CULT_710039 PE=4 SV=1 -----------------------------------AQEYGLTYDQYHLLIYLsFSEk-PPTINEISKKFNRAQNTISEKISRLEEKELVSRVDDPKDRRVTRVIITERGLDLIHTIRQERSNRVTYIALeKMEKDEIENLLTNLSILYNNLK---- ->tr|A0A1F7RCL7|A0A1F7RCL7_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium GWA2_38_11 GN=A2042_01375 PE=4 SV=1 -----------------------------------FSNVHITGPQFATLVYLSRDn-NCTMGRLKENLDLSLSTLTGIVDRMIKAGYVERQRDGNDRRVVRVRMTKKGEEVSKELNKKRHEKIITILQLLKRedqeLLIGTFERLTSHLVQNSK---- ->tr|A0A223HV62|A0A223HV62_THETR MarR family transcriptional regulator OS=Thermoanaerobacterium thermosaccharolyticum GN=Thert_00083 PE=4 SV=1 -----------------------------------LNSKNITMSRFWVLNKLHSDe-AITMKQLQSQLLLSPSTLTGLIDNLVADDLVSRWRDTKDRRLVFLKLTVKGSNLLNEILEYRTLVLKKIVSKCTKdIDLNMLNKNLETLLKMSN---- ->tr|A0A0V8GCA6|A0A0V8GCA6_9BACL Uncharacterized protein OS=Exiguobacterium enclense GN=AS033_14280 PE=4 SV=1 -----------------------------VNAF--LKQWDLSHTNLEVLRCLQTTSCTSQKEIAERIQVTDGTISHGIKRLFDRQLITRKR---KWKTNYLLLTEKGTAILQEVLPAYERFQQEQFAALTARQQEELIRFFDKLNPA------ ->tr|A0A0R2AWG0|A0A0R2AWG0_9LACO MarR family transcriptional regulator OS=Lactobacillus murinus DSM 20452 = NBRC 14221 GN=FC48_GL001553 PE=4 SV=1 -----------------------------SATV--LQQVGITNAQYDILNYVYNHTGRTQKELATTLVVTKGNITQIITKMERLDLIKRKQ---VGKAKQLFVTENGRQIYEQITPKLEKAHADALAKLDLTEQKQLLRLLKLALRG------ ->tr|C5USK5|C5USK5_CLOBO Transcriptional regulator, MarR family OS=Clostridium botulinum E1 str. 'BoNT E Beluga' GN=CLO_1452 PE=4 SV=1 -----------------KMTTVSELANRINDEFYK--QFKLTRIQFRTLYFlhVFMKEGCSLSELSKKLHISKPSSSNLIDRMVSSGLVTRISNSEDRRSIKILITSKGIKIIEQAINRDKDFRLQILNFLSNEERQTLYKILVKMEKNMT---- ->tr|J2VFA9|J2VFA9_9RHIZ Transcriptional regulator OS=Phyllobacterium sp. YR531 GN=PMI41_02302 PE=4 SV=1 -----------------------------------LLGHGFYAGQDAVMLQLAHEDGLSPSVLAKRLGVRPPTITKTISRLQTQGFVKKEGSSTDQRQAHIFLTDTGNEAIKSIEKSIRKTEKDAMKGFDKKERKAFVKMLTRLEMNLSAA-- ->tr|A0A1N6LIT5|A0A1N6LIT5_9BURK Transcriptional regulator, MarR family OS=Burkholderia sp. GAS332 GN=SAMN05444172_5026 PE=4 SV=1 ------------------------------------AALDMTPSQYGVLYILFHSGPLEQIGIARLIGLDRSTTALVVKILSERGLLEKAKSETDQRKVEISLTEAGQQCFRQCERYAQKSVEALLAPFDPAERTQFLALLDKFVSHFND--- ->tr|A0A143Y6M7|A0A143Y6M7_9LACT Transcriptional regulator marr-type conserved site OS=Trichococcus palustris GN=Tpal_399 PE=4 SV=1 --------RALDQQLCFEVYRASNGFSKMYGRA--LKPFQLTFPQYLVLLALWDADGVLIKNIGERLGMGIGTLNPIMTRLEKQDWIKKTPSLGDKRSVIVSLTEKGKRS---KRDIALSILKEISIcNFTGIEGETLMKQLKILNRAFAAM-- ->tr|A0A0R2L779|A0A0R2L779_9LACO MarR family transcriptional regulator OS=Lactobacillus siliginis GN=IV55_GL000192 PE=4 SV=1 --------RLLDDQLCVAVYNANKRFNRFYMET--LKPYNLTFPQYIALCALWENDKQTVNEIGEKLSLDSGTLTPLLRRLEQNGWVKRTRSKSDERQVIVRLSTKAKEQ---RDEIYQHVTDCQDLlAYDDVTYADSRSAVKDLSNRLASV-- ->tr|C6XKS5|C6XKS5_HIRBI Transcriptional regulator, MarR family OS=Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) GN=Hbal_1958 PE=4 SV=1 --------AKFDQNVLPWIGRIERQFSILMKEA--LAPLDLTYPEFRLVGVLWGEEEgHPQKYLAARLGLDASAVSVTLKSLEKNKIVERVRDQNDARIVRVKCAPKAYEM---TQVLSAHSEQEmSATsGFSDTEKQQLLQLLTRVSQNLSQK-- ->tr|A0A088T4A1|A0A088T4A1_9BACT MarR family protein OS=Candidatus Izimaplasma sp. HR1 GN=KQ51_01063 PE=4 SV=1 ---------------------------------------QIKGIRFKYLKEIHKRKEVTLTELADHFSISKPTVNEVINHFKANGIIEKRKSEKDKRINYISLTDIGVVLATTNTLESRRAVDRMFDKLPKKDIKTLVKIFSKL--------- ->tr|A0A0J1HCY3|A0A0J1HCY3_9GAMM Uncharacterized protein OS=Photobacterium aquae GN=ABT56_00215 PE=4 SV=1 ------------------------------------------IEQLLMLMELNYEDGLRPSVLAERMMRSKGTISSLIKHAQRNEFIASSSDPNHKNAKRLYLTVYGKKVHDELTPIIDEELEAAMDGVPAELREEIVKVMFNVIRRNH---- ->tr|J2LHX6|J2LHX6_9BURK Transcriptional regulator OS=Herbaspirillum sp. CF444 GN=PMI16_03738 PE=4 SV=1 ---------------------------HLLQDAL--RPLEILPTEYRTLSAILRKGPLTMQELAQWTAYERTRVTRILHAMEARGWIARSASEHDKRSVVVQITDRGREMFWQAKVIVDQVTDQAMSDNSEEEIAQLRHGLTVLRKKL----- ->tr|B1YJZ3|B1YJZ3_EXIS2 Transcriptional regulator, MarR family OS=Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15) GN=Exig_2179 PE=4 S -----------------------------------LLPFSLHTGQWGLIKAVAILEPVSQVALSKYLVIEKPAVTKTVARLEELGYITRTG---SGRKRLITLTPSARHAYREIDQAVQSAHHAFLQSVSFDDQSIIAAVMtqllATHRPDEQE--- ->tr|A0A0J6WYW2|A0A0J6WYW2_9FIRM Uncharacterized protein OS=Megasphaera cerevisiae DSM 20462 GN=AB840_02550 PE=4 SV=1 -----------------------------------LRPYGITYSQWVFIVYLSHHRQTSLAPIASYYQIERPAVTAIKNMFLQRRWIQEKTGQ-DRRERIISLTKQGTDTFAEINVKIRAMEHQFLASLTTKEQTDLQKLLYTLNQKEIL--- ->tr|A0A1W2EDZ0|A0A1W2EDZ0_9FIRM DNA-binding transcriptional regulator, MarR family OS=Sporomusa malonica GN=SAMN04488500_12330 PE=4 SV=1 -----------------------------------FSPYDLHFSEWGIIITLMEREPMTQRGLAAYLNVEPAAISKSLTRMERKGLIMREVGS-DRREKRVFLTEEAKKNYQVWNNIAGEHRKAVLADLDWGKKNEIYQLLKGICQATQQ--- ->tr|A0A166BRG5|A0A166BRG5_9EURY Transcriptional regulator SlyA OS=Methanobrevibacter oralis GN=slyA_1 PE=4 SV=1 ----------------------------------KAREFSIDVIDYYIILeiIHHNNNEFIQKDFAQLFDKNESSITRALNHLEKSGYIERILceDNK---SKLVKLSPTGRNIVLEVEKEVSKFDEYIFSDFSPENVKVGIKNLIDIANNS----- ->tr|A0A1B9TYR1|A0A1B9TYR1_9RHIZ Uncharacterized protein OS=Agrobacterium rubi GN=A6U92_22375 PE=4 SV=1 -----------------------------RQRISAhLADSQLTFIDFIVLSAIAEAANIPLGVIADSLDIGPSNFSNMVSLLERRKLVKRKPNGPDKRHRAILVTKRGKAVLQRASSVWIDSEEELTKQLGDTNRRIFVlQALRDLGK------- ->tr|A0A1W9IHX8|A0A1W9IHX8_9PROT Uncharacterized protein OS=Proteobacteria bacterium SG_bin9 GN=A4S14_04690 PE=4 SV=1 -----------------------------ISELNGiLSEFDLRIMDFAVLSIVETNPGIFQNEITHIVGAEPPALVLSLDRLEKANYLFRQFSPTDRRLRTLHLTTDGRKLIKKVTAKVERQERGITNAVR-GDLAQFVAGLDDLML------- ->tr|A0A177MQF3|A0A177MQF3_METMH MarR family transcriptional regulator OS=Methylomonas methanica GN=A1342_09985 PE=4 SV=1 -------------------LRTHQAFLSYAAR--HVHRLELTLPQYDVIITLGKTAGMQPKKLGEETLITKGTLTGVVSRLEDKGLVERSASKKDGRSQIIRLTEAGRAVYEQTFPEHLAHIGRLFDDYAPEEISKLEADLQRLHQAVITA-- ->tr|Q5LVU0|Q5LVU0_RUEPO Transcriptional regulator, MarR family OS=Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) GN=SPO0605 PE=4 SV=1 -------------------LRSQQLFMRAMGP--VFRAHGLTAPQWDALETLANKGPVSMNDLMRFTLSTSGNLDVVIKNLIQAGLIEKSVDPEDKRGRILQLSPEGRRKVDDFIPIHNQALDQLFSGLGTAGKRQTITALNQLRKTLTQA-- ->tr|E6W6Y0|E6W6Y0_DESIS Regulatory protein MarR OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) GN=Selin_1490 PE=4 SV=1 -------------------TEFEKSYKRAVDR--NIKKLGVSPSQFKVLKTLGERGSLKFKDVCDATLITKGTMTGVVNRLIKAGLVEKEQDVKDTRAWILSLTPKGKVDYVSLNKNYSQLVSSIFKGETEERLKQYITQLNSLQAIINQS-- ->tr|D6U5I9|D6U5I9_9CHLR Transcriptional regulator, MarR family OS=Ktedonobacter racemifer DSM 44963 GN=Krac_0830 PE=4 SV=1 ------------------------------------VGMSQL--RRQLLTLLSEIGELSHAALQQQLAVDGATITRLVKQFESEGVLSRRLDPQDNRYTLVSLTVSGQQIVAGLRAAHRLFQTQLLNGIPREEQEMVLHVLERLHANIRA--- ->tr|A0A1V1IAA2|A0A1V1IAA2_CARML MarR family protein (Modular protein) OS=Carnobacterium maltaromaticum GN=BN1423_2290010 PE=4 SV=1 ------------------------------------TECSLT--RYEIMHILAKKERVLQGDLQRAIKIDPAAVTRHLKKLEEEKCIVRERNSQNNREVYVQITPIGLTRMQACQSKTVDTLEQVYQGITNEQRKELTGIVEKISQNIST--- ->tr|A0A1E5BYN9|A0A1E5BYN9_9GAMM Transcriptional regulator OS=Enterovibrio norvegicus FF-454 GN=A1OK_15490 PE=4 SV=1 -----------------------------------LEPFKLTYPQFVVMMSLWQEQNVSVTELAQSVGLSKATVTPIIKRLQSVGYVTKTLVEGNERQKSVALTDEGKKLARAGKKVAK-QALC-ATGLTESEADTMISLSQKIRQNL----- ->tr|A0A0S9EYH1|A0A0S9EYH1_9BURK MarR family transcriptional regulator OS=Acidovorax sp. Leaf76 GN=ASF11_23965 PE=4 SV=1 ---------EPEESVGYLMRKVMSSIRTQ-ADA-QLSTHDLTYAQWLPLFKISRCDQTTVASLARDLETDPASMTRAMDRLEAKGLVVRERSTTDRRVVRLTLTPDGDQVASRVPAVLADVLNVHLSDFSHAEWQLLLSLLRRMLVN------ ->tr|A0A0F7JK93|A0A0F7JK93_9DEIO Uncharacterized protein OS='Deinococcus soli' Cha et al. 2014 GN=SY84_05420 PE=4 SV=1 ---------------------------------ATASGADLTPTTRDllftLHRSAPPEGLTPGE-LAALLAVSPASVTGSLDRLETRGLLRRAPDPQDRRAQRIHLTDTGRDLVRMHLPVH---LRREEDLLSPLSASERQQLEQ----------- ->tr|A0A136L801|A0A136L801_9CHLR MarR family transcriptional regulator OS=Chloroflexi bacterium OLB15 GN=UZ15_CFX003002399 PE=4 SV=1 ---------------------------------RETGNEEATMRQISVLMQLRKHPVTASE-LAKRNKVSLQASSVLVQGLVERGWLTRVRDPKDRRQWLLEVTPEGIASAEAAKKQLTGIIAEILSDLPSEALKSASVFLP----------- ->tr|T0QZ00|T0QZ00_9PROT MarR family protein OS=Bacteriovorax sp. Seq25_V GN=M900_0232 PE=4 SV=1 --------------ILAANIRTTKLFDDLITKGIAQ--YGISKPQFDImvFIYFGEEKKTTVTEIAINNSVSKANVTGIMNRMITQGLIQSVVDQKDARVKNVTLTEKGEELMKTTVPVYQDLIRKTLSPFSHAEKELLLKQLKHIEGCIR---- ->tr|F2J6N6|F2J6N6_POLGS MarR family transcription regulator protein OS=Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1) GN=SL003B_410 -----------------LIRRIYQIFLYCFDEA--MAGLHLTPVTWILIATARNFPGLSVTELARRAAVDKASCGRTATMLEKRGLLLIRKSEADGRQKLLELTAAGMALAIAGEGRIELLRSLLLDQLDPDEGAQFVAQL------------ ->tr|A0A0B5DXQ0|A0A0B5DXQ0_9RHOB MarR family transcriptional regulator OS=Celeribacter indicus GN=P73_0307 PE=4 SV=1 -----------------LLRRAYQVFLFFFDDT--MKGLNMTPLLWILLTVTYCYPRRSVTDIAELSRIDKASCGRAATLLEKRGLMRIGTGEKDRRQRVLELTPHGHEVVLDGMSRTLEMQKKLLQCFDQEEARQFSHTQ------------ ->tr|R6MF15|R6MF15_9FIRM Uncharacterized protein OS=Acidaminococcus intestini CAG:325 GN=BN610_01556 PE=4 SV=1 ---------------------------------------------NRILFELYENERLSAKYLCNLLLLDKGYISRVISGFEKKNMITRKASSTDGRSQDISLTEYGIDEAKRVIEITYNKIFEMIENLNKEDCDAVCNAMICIEEKL----- ->tr|A0A1F8VGG2|A0A1F8VGG2_9BURK Uncharacterized protein OS=Curvibacter sp. GWA2_63_95 GN=A2037_00435 PE=4 SV=1 ---------NPEEDAIQAMLRMFEALKGQMTQSLAQTGIALSPLHLHILSHCKAHPGGNQQALVQASTRDKGQIARITKELEAQALLRRSPDPQDGRSQILEVTPVGLEACAVFEAQHTALVQRMFASVAPEQLAVFTAVARRATAQ------ ->tr|W7AR71|W7AR71_9LIST Putative MarR family transcriptional regulator OS=Listeria aquatica FSL S10-1188 GN=MAQA_11836 PE=4 SV=1 ----------------------------------ESDKKEITTAQLIALSTLKREPHLTLGELAERMKVSKSTASGIVDRLVRAGFLMRNRVEDNRRTLNLELTKLGEQKTAETYALFFDRLEPL-LDVGEESLLSMLETHKRIIEILER--- ->tr|A0A1F2Y5M5|A0A1F2Y5M5_9BACL Uncharacterized protein OS=Alicyclobacillus sp. RIFOXYA1_FULL_53_8 GN=A2201_08225 PE=4 SV=1 ----------------------------------VVQRFHMTASQLFILRYVDKHGPTKASDIAKSAGLSPGAVTQVCDELVRIQCIDRTRSDDDRRVVYIEVTDVGRDRLNEIRQTQFAGTEHILAQLGPEDAENFVRIVGRVVEIAEK--- ->tr|C7HW92|C7HW92_9FIRM Transcriptional regulator, MarR family OS=Anaerococcus vaginalis ATCC 51170 GN=HMPREF0078_1543 PE=4 SV=1 ---------------------------------------GVTTLQLKMIMTLSASdESVSIGNLGKSIGVNGGNISNICKKLEKQGFVDRNRSDEDERVVNVKLTQKGFDAAEKVSKYFDKIRPKEDEKRINSNLKTIINELDSLDNLLDD--- ->tr|V7I6P1|V7I6P1_9CLOT Uncharacterized protein OS=Youngiibacter fragilis 232.1 GN=T472_0203925 PE=4 SV=1 ---------------------------------------GLTPNQARIILIMSLEGSATMGRISDSASIAGGNLTNLCKVLENRGLVERGRDPDDDRKVLMRLTQSGSETAQRLDRWLTTRLEDRLPEY-RGELTEIAEALEKLSEMIIE--- ->tr|R6C7Y1|R6C7Y1_9FIRM Transcriptional regulator OS=Ruminococcus sp. CAG:579 GN=BN718_01347 PE=4 SV=1 ---------------------------------------GITNMQAMMLFMIKSEKAISVGALSSIFNMTHSNASALCKKLERDGLVCRTRSKTDERTVLITLGERGEEVLSRMLK-NGAGISDSLGEIPQDRLDTIIETMNEATHMLSQ--- ->tr|A0A1C5WFE2|A0A1C5WFE2_9CLOT Staphylococcal accessory regulator Z OS=uncultured Clostridium sp. GN=sarZ_1 PE=4 SV=1 ---------------------------------------GMTGIQGLVLMEVANDEECKLGALAQRLLMTNSNLSAIIKRMEEHGWIRRCRSPQDERIVYVRLSNEGAAILADIKKRMDAKL-DFLKQEDEESIKQMIQSLKRLDDLLQE--- ->tr|A0A1C0BSE9|A0A1C0BSE9_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_05665 PE=4 SV=1 ---------------------------------------GLSKTHTLVLREVRTCEPITLNELSSNLSKVPANMSITVSELEDQGYLERERFVDDRRVTKIRLTEKGAEAVNLFDTYMEKNLHEMIED--EKTLKDILEKLESVYEKVKK--- ->tr|A0A1B7LZU2|A0A1B7LZU2_9MICC Uncharacterized protein OS=Enteractinococcus helveticum GN=A6F49_09385 PE=4 SV=1 ---------------------------------------KLSFFEYQVLEHLSSIEG-AmsMTQLATRCNSSLSRLSHVARKLEGRQLLTRRLSEEDKRVTVAELTEEGRYLVDGIREIyRQSVETRVLQSLSPEELRQVTGLLDSMLRKNE---- ->tr|R5CF02|R5CF02_9FIRM Transcriptional regulator MarR family OS=Firmicutes bacterium CAG:791 GN=BN785_01711 PE=4 SV=1 ----------------------------------DMNESDLTFSQMEILFYLEKHADHaiNQQELCDAVQVSHPTMIGLINRMEEKDLVVRRTDPLNRRSRYIEMTQKSQEILRQTRERRHRNDRMLVKGFTDEETKELNRLLGMVYRNMQ---- ->tr|A0A0R1JZC3|A0A0R1JZC3_9LACO Uncharacterized protein OS=Lactobacillus namurensis DSM 19117 GN=FD30_GL001368 PE=4 SV=1 -----------------NIGRNLKTLNNLVEKKLNNdlrsLGVSLTGTQMSVMMWLHNNQGVPltQKQIETELKLSHPTTRGINKRLVEAGLIETQVVAEDKRQIQLQLTPKGRDLLDSYSHQLKMKVDAveakMLTGIDANTQTILLSSIRTMIRNM----- ->tr|A0A0F4KP22|A0A0F4KP22_9LACO Uncharacterized protein OS=Lactobacillus mellis GN=JG29_08470 PE=4 SV=1 -----------------SLGPLIKVANNLIEKELNNnmrqLFteFNLTGPQVALLTYLYEAQSRTvsQKELETVFVISHPTIRSIVKRLEQRQLINISTLKSDRRQTILSLSASGSTLIKNNISKIYQVMNHinqkITQDITPNEQQQLIILVQKIVHNF----- ->tr|A0A0R2A5N1|A0A0R2A5N1_9LACO MarR family transcriptional regulator OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL000434 PE=4 SV=1 -----------------LIGPKLKAVNTLFEKALSKridkTNspKRLTGGQMSVIAYLYDNPDDViyQRDLEKIFNLSRPTINGIIKRLSENGSIEIVPDEKDKRYKRIMLSKEALDAMIKYRPAFEQEVKQveneMTQGLDEKQVQDLKHLLDVCRDNL----- ->tr|W7SRH2|W7SRH2_9PSEU MarR-family transcriptional regulator OS=Kutzneria sp. 744 GN=KUTG_00610 PE=4 SV=1 --------------------------------------AGISHSHFKVLALLAGAPDHTmgLTKLSQALRFHKSRLSHALAKLEAGGLLRREDTPEKGRAYQAVLTRAGLRLVNRALPLqDAFARDTVLAGLSREQIKQLRAIAEIISGNLEH--- ->tr|A0A0Q7RR45|A0A0Q7RR45_9RHIZ Uncharacterized protein OS=Ensifer sp. Root142 GN=ASD52_25720 PE=4 SV=1 ---------------------------FDLNGAVEaLAQVDARPISLSVLLCMVEKPGLTSAEICRILGMQRANIVQFLTDLEAKGLFTREAEASDQRVQRLFPTQAGREAAADWLHRLNEHEDRMLERLDAQERAELRRLLSKVW-------- ->tr|A0A1E4MDZ0|A0A1E4MDZ0_9SPHN MarR family transcriptional regulator OS=Novosphingobium sp. SCN 66-18 GN=ABT11_12380 PE=4 SV=1 ---------------------------VADALFSEtFGEMEITAAQYAILMVVRHNPGCRTSTAGSLLGITPNNLVPLLDSLTARGYIRRTLSTTDRRVRHLRLTPRGQELCAALVARHEAIQAKLEERMGHGQVAEFLRLLTLYC-------- ->tr|A0A1U6J3D8|A0A1U6J3D8_9MICC DNA-binding transcriptional regulator, MarR family OS=Arthrobacter sp. P2b GN=SAMN06272721_12259 PE=4 SV=1 ---------------------------RMFAAFHRrFADSGLTPAAYATLATIDRNPGVRQGRIAEELGLQNSNMVNLIKSLVERGFVERHRSASDNRVFTLTLSSAGKLFIEKMNERALALDAEYTRSLSDEERRTLIELLGKMI-------- ->tr|A0A1V4IFL3|A0A1V4IFL3_9CLOT Multidrug resistance operon repressor OS=Clostridium chromiireducens GN=mexR PE=4 SV=1 -----------------------------------LSDRNMSFSDAMVLIYVSANPGTIQDDIGSNLSIDKSVVARSIKSLEALGLLTRTEDLSNQRVKKVYTTEAAKEFKTYWNKIISQWNKTILADLTPEERSMVIYANYKIKVSAI---- ->tr|V4NPX8|V4NPX8_9CAUL Uncharacterized protein OS=Asticcacaulis sp. YBE204 GN=AEYBE204_18540 PE=4 SV=1 ----------------------------------RLRDLGVSESGWMTIALIAKSeTPPSQSDLAQALSVEGASMVSMIDRLVKLGLVERVGSEADRRVKHIVLTDDGHKVFARVKQEADAFRAETVSRLDPEKLAVAADIMEQLQNFIN---- ->tr|A0A176TIB8|A0A176TIB8_9LACO Uncharacterized protein OS=Pediococcus parvulus GN=A7K95_08110 PE=4 SV=1 ------------------VNHQLHVLANMSSRRFSeaflnN---DITGKQGGILHYLLWNAgKREiyQRDVekNFSI--RRSSVTSLLKKLEDKQYITRESVEGDARLKQIVLTPRALKLRKSVIQGSYDFEDKLLQNVSAADIEVWQKVTKQMIANLSE--- ->tr|A0A1C5VQU5|A0A1C5VQU5_9FIRM Salmolysin OS=uncultured Roseburia sp. GN=slyA PE=4 SV=1 ------------------ICRNLKIFDCMMNDHRNkdmegS---GMTGRQFEVLSYLVE-HqNENvkQVMIekDFQL--SNPTVSGILKRLEQNGLICRISEDTDKRCNRIVVTKKAQRALIQAGEKWEILEEKLFDGIAKEEEQIFDEILGKLCRNITK--- ->tr|A0A1T4XPX6|A0A1T4XPX6_9FIRM DNA-binding transcriptional regulator, MarR family OS=Gemmiger formicilis GN=SAMN02745178_02161 PE=4 SV=1 ------------------FGALLNQTSRLIRRALDarinaEVSSELSGVRGMVLGDIVRAeRqGRDvyQRDIeqWFNI--RRSSVTAMLQGMEQDGFITRSAVAKDARLKRLIATEKGRACHKQIEASIARFEDDLQSGIDPQQAAAARAVLEQTLRNAQH--- ->tr|I7HEC7|I7HEC7_9HELI Putative MarR family transcriptional regulator OS=Helicobacter cinaedi CCUG 18818 = ATCC BAA-847 GN=HCBAA847_0432 PE=4 SV=1 ----------TQYLIGHHIGRTARSFQEFFIK--ELKAHNLSFEQGVILFMVSENPKIHISHIARELHKDKATISREANSLVNKGLFVKTQDSCDKRTTLLVLTPNGENALNLIKDKIKKLESLLFSRFSQDEINTCLNVLENMRLAI----- ->tr|R6PA12|R6PA12_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:274 GN=BN582_01227 PE=4 SV=1 -----------------------------------LIDVNISFMEGLMISYAGNKPDQNQETLASLSGVDKYRTAKFLSSMEERGLIVRKANPENKREKLVALSEDGKEIYEKFNKWSEEWRELCFKDFNKDEINIFMGLLDKMIKNLE---- ->tr|A0A1V0LQP4|A0A1V0LQP4_9FIRM MarR family transcriptional regulator OS=Eubacterium limosum GN=B2M23_04685 PE=4 SV=1 -----------------------------------LGGMQLNNTEQSILLYLKHNDGVNQHAIARFFQFNKTTVAKTLSALEDMGLIKRETNCESKREKRVYLTEAGNKAVVLIKESRRQLEEEVMAEFTEEEKALFDELSERIAVKVW---- ->tr|K2E8X4|K2E8X4_9ZZZZ MarR family transcriptional regulator OS=groundwater metagenome GN=ACD_18C00328G0001 PE=4 SV=1 --------------------------------------NSLSYIQFQTLSFLLKYNSPTMREISEYTHITAPSTTILINNLVRMKLVLRIHDEFDRRLIRLIITTSGKEELEKGVLAVKKHLKNVFSKLSKKDRHDFMRVLIKLSNFFNQV-- ->tr|A0A151EKN3|A0A151EKN3_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SG8-52-1 GN=AYK20_06260 PE=4 SV=1 --------------------------------------FGITGVQLMTLHFIKHNNNCKTSEIANFLSVSAPDATRIVETLVKKGFVERINDEKDRRIIRLLIKEEGKKVVETIKQELALSFSKILEKINEEDAKALLRGMKALSNALKEL-- ->tr|B8FL86|B8FL86_DESAA Transcriptional regulator, MarR family OS=Desulfatibacillum alkenivorans (strain AK-01) GN=Dalk_3031 PE=4 SV=1 -----------------------------------LEPMGLTGAQANALGILFRKKNLSLGEFAARAGIGKAAAVSMIHRLTETDFVTAVPDPNDARKNIINVTDKAIKVIAPAMTIVRHLESTVEEALGEDVLKTLVDALKVVR-------- ->tr|A0A0C1S8D8|A0A0C1S8D8_9ACTN Uncharacterized protein OS=Streptomyces sp. RSD-27 GN=PL81_27605 PE=4 SV=1 -----------------------------------LRPFKINVPQYGVLFELSRQSGLSGAALARRCMVTPQTMSSVLSTLEGRGLVERTPHPIHLQILEVRLTPAGKTLIREADVVIEEIEKLLDGCFAPGEARSFLEQLERCEKAVT---- ->tr|T4BE11|T4BE11_CLODI MarR family protein OS=Clostridioides difficile F501 GN=QOE_3967 PE=4 SV=1 -----------------------------------CQQYGLTLQQMHVLMELVRTPGLTAGQLSDRAGILRTNFPSVCRKLEDRGLIERQRSQTDRRSLKLRVTDEGRALLADVDGEV---QRRYGEAFAAEPPETFDAIIGGFRALAD---- ->tr|A0A229TC41|A0A229TC41_9PSEU MarR family transcriptional regulator OS=Amycolatopsis sp. H5 GN=CF165_13450 PE=4 SV=1 -----------------------------------LRKLGVSGSLYAVLANLQVTPGLTGAELARVVGVTPQAIAALVSKLSGRGWIERRSHPRHGNVQELHLTDRGRGELAGANRLMADLDGYLQQSLGDENYRQLRRLLGEVVELLP---- ->tr|K5AD31|K5AD31_PAEAL Transcriptional regulator protein OS=Paenibacillus alvei DSM 29 GN=PAV_1c01990 PE=4 SV=1 ---------------------------------------NVNMTQFAVLDLLFRNGSMKVTDVAKELRLTPGAVTGITDKLTQMDYVARNRDKLDRRINYLELTEAGRQKVKAVEIQREFVFARYFEGIPDEDLLHFLHICQQVNLNLD---- ->tr|A0A0V8M571|A0A0V8M571_9CHLR MarR family transcriptional regulator OS=Dehalococcoides mccartyi GN=DA01_00045 PE=4 SV=1 ---------------------------------------DVPLAQMKSLFIIIGKGEMNLGALAQSLGVTPGDVTGIVERLVEQGLISRKPGAEDRRVTWLSATDKGHALVTNLVESKSEHMADILEHMSLDGLVSLEKGLKELISAIR---- ->tr|A0A0F5Z341|A0A0F5Z341_LISSE MarR family transcriptional regulator OS=Listeria seeligeri GN=UQ68_08520 PE=4 SV=1 ------------------------IHQAISELS--TSTADISIEQFFVLREIAENDGIGASDLALCLLANKSAVTPKLKKLEEKGYIKREKNPTDKRAIILTITKKGNEVYQECEQKLENLVNDWLEILGEKDSEQFLNLYEKITKSVIQT-- ->tr|W7BRY5|W7BRY5_9LIST MarR family transcriptional regulator OS=Listeria floridensis FSL S10-1187 GN=MFLO_13183 PE=4 SV=1 ------------------------IDQAIEQVD--FYGKRISMEQFFMLRELCReENGVSATQLSCRLNVNKSAVSAKIKNLEEKGFLVRSQNPFDRRAVVLHVSDQGREIFKVCEKAMQDLIGDWLRRFGKENSEMFMTLYDRLIDLVIVN-- ->tr|R7FRU3|R7FRU3_9CLOT Transcriptional regulator OS=Clostridium sp. CAG:288 GN=BN588_01403 PE=4 SV=1 ------------------------LIQKIYTQGELNPFIQLVQSDSRILLYLFYHPSCHPSDISKSLNMSRPNVTANLKNLEDNEMIVRTLNAKNRREIYVTLTAKGMQEFNNRMSKIIGLFQDWLKLLGEEETEHLIRILEISSDMNNIG-- ->tr|A0A069RIB3|A0A069RIB3_CLOLI Uncharacterized protein OS=[Clostridium] litorale DSM 5388 GN=CLIT_8c00540 PE=4 SV=1 ------------------------DYNYFINKR--LRELQIKKNDVKVIKNINQNHGISQNEICVLLKEDKVTVAKSVKKLEALGYIKRTNENADKRIVTLYVTEEGQGVRRKIMKIFEDLKTIFMKDLSPKEQEMAVALLAKMSKNMHDE-- ->tr|A0A1W9VTC4|A0A1W9VTC4_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_7 GN=B6229_02995 PE=4 SV=1 ------------------------QIN-----Y--GDDESISFSEAQVIEEIIRHKDSNMTDLSKELGVTKAAITKTMKKLENKGFITRFKQEFNKKEIFVSITKKGHEIYKHYQEYMyTNLFGELFQmfsAVDPSHAEMIFQFFNSVDKSLSKI-- ->tr|A0A0Q7SCE6|A0A0Q7SCE6_9BURK Uncharacterized protein OS=Pelomonas sp. Root1444 GN=ASD35_25540 PE=4 SV=1 ------------HTLGYAIARAAVTTNQLFSQGVG--EpLGVRPVEFTLLQLIFSNRNTTQKRLCDLLRVPAPQMTLILDRLQERGWVERERDANDRRALHLRLTAEGERLAEESLVALQVAEQALDRVLSSGERLLLQELLAKVAR------- ->tr|A0A1B1NDX9|A0A1B1NDX9_9MICO Transcriptional regulator, MarR family OS=Serinicoccus sp. JLT9 GN=SGUI_2230 PE=4 SV=1 ------------RRAGFLLATVGRRTDAAWGGFLR--SRGMTNAEFAALAVLVDGS-ASQVELARQLAIDARNAGATVRKLRERGWLSSAADTTDRRRVVLTLTPDGQRAWDDLQAELRGSRSDYFGALDDPERAELERLLNKLNDA------ ->tr|A0A1Q9ATP7|A0A1Q9ATP7_9RHIZ Uncharacterized protein OS=Rhizobium oryzae GN=BJF93_17065 PE=4 SV=1 ------------NCLVLNTVAAARTLVRKGDARFK--PFGVTVQQFSLLAAIRFNPGEPVMSLAQKIQLDRTSLTRNLDLLERKGLVQRAADAvGNARI--CELTKEGSVLLDQLLRVWQQAQSEISQGFTEDEADTYLRLAKDFADR------ ->tr|U6S1U2|U6S1U2_ENTFL Transcriptional regulator, MarR family OS=Enterococcus faecalis VC1B-1 GN=D350_01616 PE=4 SV=1 ---------EFEIKRGETMNQQQEALKAYIGLLRtshrleqlakqDVTCYDLNITEFSVLELLLHKGPQTIQKIKEKILIASSSTTYVIDQLHKKGYVTRTPSEKDRRITYVELTEAGKTLIEEIFPTHAKRIAEAFEQLSSEELTLLQKTLRKITNE------ ->tr|A0A1B8XBQ6|A0A1B8XBQ6_LEPIR MarR family protein OS=Leptospira interrogans serovar Copenhageni/Icterohaemorrhagiae GN=A9P81_1769 PE=4 SV=1 -----------MGTHYKGNSRETAVLNAFIKLSRcsdsirqleekVFSKYGLTTGQFGCLETLLHLGPMCQKEIGQKLFSCEGNITQIVDNLEKRKLVQRVRSEEDRRYIIIHLTSEGKKLIQKAFPDLLNSLVHKFGNLSENQLLDLGDFCKEIGLK------ ->tr|A0A1F8IJA1|A0A1F8IJA1_9PROT MarR family transcriptional regulator OS=Caulobacterales bacterium RIFOXYB1_FULL_67_16 GN=A2352_01930 PE=4 SV=1 ------------------------ALQLSLDIYAEEMGADgLTQRQFAVLEAASLKAGLTQTELVRMTGIDRSTLADLVTRMTTKGLLERERSTLDARAKAVRLSAEGAARLEAARPKVETADKRIMALLPKGQREVFLSQL------------ ->tr|A0A1K1RGR6|A0A1K1RGR6_9BACL DNA-binding transcriptional regulator, MarR family OS=Paenibacillus sp. UNCCL117 GN=SAMN02799630_06089 PE=4 SV=1 ------------------------------ASYAKLADSRISSSQYFILQALVHEGPLTCSHFAHVLDVTLSAVTNLSNKLVKNGYVERIPSETDRRQVYLRITEQGREMERRLLERYELLTEGLWEEFSGPEVELLIAAYKKMIAHV----- ->tr|G8P1S4|G8P1S4_GRAMM Regulatory protein MarR OS=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8) GN=AciX8_1558 PE=4 SV=1 -----------------------------------LQPLGITAAQLRLLRAVQDAPGISGAKLADICSVTPQTGQQLMMKLESNGWITREKNPANERVLLARLTKKGEKMLQHARAIAEVAHHKLWQRIDPAKLAVFDEVLAISCEN------ ->tr|A0A0J8Z1F3|A0A0J8Z1F3_9FIRM Iron dependent repressor OS=Coprobacillus sp. 8_1_38FAA GN=HMPREF0979_00850 PE=4 SV=1 --------------------------------------------------ELEEKNQKVKvSDVSEVLNLPRPGVTRTIHAMEEKGYLKKETAKHDGRVTYVTVTKEGKMIFEKYNKDYFQKLALCLNHVSNDEADCMIQTIEKFYE------- ->tr|A0A1X7FTA2|A0A1X7FTA2_9RHIZ DNA-binding transcriptional regulator, MarR family OS=Rhizobium oryzae GN=SAMN02982989_0783 PE=4 SV=1 -----------------------------------LAPMQMTGIQYTVLSVIGSRDGLSSAELSRRFFVTPQTMNELIGGLQRRNLITRKEDPANRRILRMSLTNEGKRMIKACDAAADIIERDVFSFLPQESYEQFRDLCRQIARNLR---- ->tr|A0A1M3P5S2|A0A1M3P5S2_9SPHN Uncharacterized protein OS=Sphingobium sp. 66-54 GN=BGP16_15100 PE=4 SV=1 -------------------------------------DAGHSQVRWEILHAISVDSGqCTLMEVAGRVGLEAPSIVGAMAKLEAGGFIERRQDGNDRRSRLIFLTDKGRAAVTAMAAVVKEQRERIWQGIPDADIDAMLRVLSHLRSRLLEA-- ->tr|A0A0S3PY08|A0A0S3PY08_9BRAD MarR family protein OS=Variibacter gotjawalensis GN=GJW-30_1_03390 PE=4 SV=1 ----------------------------------ALAAHDLNAPQYSVLEAIQNNPGATNADLAREALVTAQTMGGIVQALELANCVERVP--GEARRISNRLTRTGADILRRARRDVQKLERDMVDGIDKSKLESFSKTLSAMTDKL----- ->tr|Q2LXK3|Q2LXK3_SYNAS Transcriptional regulator, marR family OS=Syntrophus aciditrophicus (strain SB) GN=SYN_00342 PE=4 SV=1 ---------------------------------------NISHAEYRALQAALDCDICSMQDIAKSAGVTKSGATRIAKRLEGKGLAKRQQDRKDGRICCVTLTEEGRTLLKRIEDRLLNKMRKILVNMDTTVREILILSLSSFVQSA----- ->tr|A0A1V5XYU3|A0A1V5XYU3_9FIRM Transcriptional repressor MprA OS=Firmicutes bacterium ADurb.Bin182 GN=mprA_3 PE=4 SV=1 ---------------------------------------DLSLVEFMALKKIQESNEITIQEVGNAINFTKSGASKIIDRLEKKGYVVRMNSPADGRVCCVLTTDKGKETVAGIMENYTLYLDDVLKGIDPQQIGQIRETLIMLVDTL----- ->tr|A0A0M9VH75|A0A0M9VH75_9FLAO MarR family transcriptional regulator OS=Flavobacterium akiainvivens GN=AM493_03885 PE=4 SV=1 -----------------------------------LDPLNLTQTQFVLLAALGwlsRENdNVTQVDIANQGNADRMMVSKVLRTLEEKKFISRHEHKTDTRAKVIKLTDEGAKVLQEALLAIENADVEFFSILGTDKLSVFNVNMV----------- ->tr|A0A0Q4S9Q7|A0A0Q4S9Q7_9FLAO MarR family transcriptional regulator OS=Flavobacterium sp. Leaf82 GN=ASF10_07455 PE=4 SV=1 -----------------------------------LEEHNITHSQFVLMASIHwltLHAqEVTQIILSAHTKIDPMTTSTVLRTLQQKSLIARKEHATDTRAKVVVLTDLGKKIIKKAIVTVEDFDRKFFAVTGV-NTKDLNQNLI----------- ->tr|Q8TU97|Q8TU97_METAC Transcriptional regulator, MarR family OS=Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) GN=MA_017 -----------------------------------LAQYRMGWVHYAILMSLFDHEGCSQESLARSGEFNKTMITRSILRLEEEDIIYRKIDLDDKRVKRLYLAKKGKKLRYKMEKIRLELNILLLKGFDSEELASVTEIMRKIALNASR--- ->tr|A0A1M6JNX9|A0A1M6JNX9_9FIRM DNA-binding transcriptional regulator, MarR family OS=Dethiosulfatibacter aminovorans DSM 17477 GN=SAMN02745751_02676 PE=4 SV=1 -----------------------------------LKAINMTTLQSIVLINIKRHEGVNQNELASVVGIDKASVSRVIRDLENRNLLFKEIDQSDRRHFRLFLTDKGKEEVEKSVEIQMRIWLDCMKEINSEELNISKEMMIKLYSNINE--- ->tr|A0A0R1ZUN2|A0A0R1ZUN2_9LACO MarR family transcriptional regulator OS=Lactobacillus malefermentans DSM 5705 = KCTC 3548 GN=FD44_GL000493 PE=4 SV=1 -------------------------------------SYGLTGVQLSTIDFLARQKNQsvLQKdiEVEFSIRRS--SATTLLQRMAQKELISLSKSAADERQKEVHLTAKSQDLIQVVGDYLEVQQNSLEANFTPTQLRAFSSILTFLKKD------ ->tr|E6LD73|E6LD73_9ENTE Transcriptional regulator OS=Enterococcus italicus DSM 15952 GN=rmaI PE=4 SV=1 -------------------------------------QYQLTGTQMSILNYLYEHSGEdiSQKdlVTEFGVKGS--TMSVIVHRMEERNLVTRQIV---GRQKYLNLTPNAQTYITAIQNFFQKDNERLIAGFDTNELAVIAKFLQQIGGK------ ->tr|A0A1U9NDK1|A0A1U9NDK1_9GAMM MarR family transcriptional regulator OS=Cellvibrio sp. PSBB023 GN=B0D95_17460 PE=4 SV=1 -----------------SLRRVIRAIDLHSRQLV--KTASVTGPQLRLLQLIRSQQGGTVKELADAMSLSQATVTSIMDRLESRDLIARVRSQTDKRKIHPQLTASGNALLDTAPTPLQDSFVRKFDQLHTWEQHMIIASLQRVAEMMD---- ->tr|K6T1R9|K6T1R9_9CLOT Transcriptional regulator OS=Clostridium sp. Maddingley MBC34-26 GN=A370_03930 PE=4 SV=1 ---------------------------------------EVTLAQCHALVEIGRAKNISLKDLSTLLILDISTMSRTVDSLVKKEFVYRATSEIDRRSVDIKLTEKGLNLFHDIEKKMNEKYKNIFNQITSEDQAIVFNGLNIIIEAITKN-- ->tr|A0A1D9BI60|A0A1D9BI60_9NEIS Uncharacterized protein OS=Jeongeupia sp. USM3 GN=BJP62_17485 PE=4 SV=1 ---------------------------------------AINLSQNSRILEMmYRVGPMTQSTLGQILNFEKSWISRMVDQLVAEGWVERTPNPQDRRSNILVLTAAGQTHAKDIGTMFDKHARDVLDRVSDEARDELLRAMTHLGNALPPR-- ->tr|A0A1R1C902|A0A1R1C902_9BACL MarR family transcriptional regulator OS=Paenibacillus sp. FSL H8-0548 GN=BK133_30500 PE=4 SV=1 ---------------------------------------DISLVQSHIIYEIDRKHNPSIQQVADSLSIDITTFSRQVQSLVKMGVVKKTPLPEDRRIYILSLTTEGKYISTVIDAQMNDYLKEVFSHMSEFERDMVINSIKLLNESMAKS-- ->tr|A0A1S1BTL6|A0A1S1BTL6_9LACT Uncharacterized protein OS=Aerococcus sp. HMSC035B07 GN=HMPREF2705_01445 PE=4 SV=1 ----------------HLIFQLANLQKKYLFER--LKEVDLNPIQAQTLHYIYREAGPIQRSLATYLGKHEATISNILNVLEDRGYLYRQTASDNSRQKQIFLTASGHEQVEKINGIFKDLEAELCSDLSSQDRAKVLQVLTDQRD------- ->tr|A0A1Q9NNI4|A0A1Q9NNI4_9ARCH HTH-type transcriptional regulator Hpr OS=Candidatus Heimdallarchaeota archaeon LC_2 GN=hpr PE=4 SV=1 ----------------------------------------LFAGQEMVLTRLAKKPNIVLNELAGFLKTKPPTVTKVTKGLQDQGFLIMTKDEKDKRVTRVNLSRKGENLQEEIARIWGIIEKETFKSFSIEERVIFKRLMQQIIENLES--- ->tr|J2YKG0|J2YKG0_9PSED Transcriptional regulator, MarR family OS=Pseudomonas chlororaphis subsp. aureofaciens 30-84 GN=Pchl3084_3461 PE=4 SV=1 ---------------------------------------NLAQTPFFVLLLLKRNpgG-LSIGALADGVAVASQTMTRAIKQMEAAGLCTKHPDPDDGRYWIVRLTPEGDSTLGRVLPKHYEWVARFMRHFNEDERELLVKLMMRVAPALRT--- ->tr|A0A1F3TSK9|A0A1F3TSK9_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium RIFCSPHIGHO2_01_FULL_40_29 GN=A2622_13935 PE=4 SV=1 ---------------------------------------GLSQARFLALIILEREnmKQQMPVEIARKMGTTKKNTARLLAFMEEDGLITIKPHEIDGRATIVKITLKGSKRLNDVLPKYYKIMNSMMKNISEKSKSTLIQILNQIET------- ->tr|A0A1N6LUB5|A0A1N6LUB5_9BURK DNA-binding transcriptional regulator, MarR family OS=Burkholderia sp. GAS332 GN=SAMN05444172_8813 PE=4 SV=1 --------------------------ARSVTKALKPFDVNLT--CWRILALLHRMGSLTTTELSDMSAIERSALGRTVDTMQASGLIRKVGRSDDQRMQDVEILEAGTRLYLEILPIVKRINDHAIWNVSAADLDRCISILKDVRSNLS---- ->tr|A0A1Y1T6H0|A0A1Y1T6H0_9FLAO Transcriptional regulator BlaI/MecI/CopY family protein OS=Zunongwangia atlantica 22II14-10F7 GN=IIF7_03951 PE=4 SV=1 -----------------------------------LAKLQLSYPEYLVMLMLWENN-eVNIGQIRRQLYLNKESLLPILNALQQKSFITLQDQDPDTLEAKVSITKTGLALKTKAKRIPFSLSR--VLNTPVEELGSMQLLIKNFLSRFEKK-- ->tr|N6W5U0|N6W5U0_9ACTO Uncharacterized protein OS=Actinomyces cardiffensis F0333 GN=HMPREF9004_1356 PE=4 SV=1 --------------------------------------FGLTLSDYNVLLALWESPHHAlrMGELAQRVIFSPSRLTYITTHLERDGWIEKTSVKEDRRSSCACLTSQGEEVVKKANALHQgMIREYLLEGFNEEEICDIVRIVQGFGDKLS---- ->tr|A0A1A0QR96|A0A1A0QR96_9MYCO Uncharacterized protein OS=Mycobacterium sp. 852014-51730_SCH5271717 GN=A5762_12855 PE=4 SV=1 --------------------------------------HDLSAMDLRVLSVLLKAPTGFvrMGDLAKEVGLLPGHLTKRVQRLEERRLVRREKYPHDRRVVMAAITDEGRTIAAKAAMTIArGVRADLGGSLSSAKVSIIEKNCGRISAQFK---- ->tr|A0A0J0UY69|A0A0J0UY69_9ACTN Transcriptional regulator OS=Actinobacteria bacterium IMCC26207 GN=IMCC26207_10683 PE=4 SV=1 --------------------------------------CDMCLSEFEILLHLSESPTKSrrMTELAELARLSPSGLTRRFDLMLKRGWVNRERCDQDRRGVTALVTKEGLKQVQMATPVYLrVQDALFFSQLVSEQLAALQGVSESIARAAE---- ->tr|A0A1S2IR30|A0A1S2IR30_9MICO Uncharacterized protein OS=Curtobacterium sp. MMLR14_010 GN=BIU98_08130 PE=4 SV=1 --------------------------------------AGISTPEFEILIGLHRQVDHRlrVRDVAAGIGWEKSRVSHQVTRMVSRGLVERTDCPTDGRGSWVVMTPDGRRAVLAGIRAHTaALEQLFWRPVADDA-DTLRSVSARLQSALG---- ->tr|A0A0S2F6I6|A0A0S2F6I6_9GAMM Transcriptional regulator marR/emrR family OS=Lysobacter antibioticus GN=LA76x_1016 PE=4 SV=1 -------ELDLEHFL-P---YRLSVLSNRVSSAIarvYSERFALSVTEWRVMAVLGRYPGLSANEVAQRTAMDKVAVSRAVARLIEAGRLERDTHDDDRRRSVLQLSLDGYKIYDEVAPMALAFEQRLLIGIEAPEREALFRLLDRLDELEM---- ->tr|A0A1M7JET2|A0A1M7JET2_9RHOB DNA-binding transcriptional regulator, MarR family OS=Roseovarius litoreus GN=SAMN05443432_108153 PE=4 SV=1 -------ALILHDFV-P---FLLNEAAETVAKRFssfYVDRYSMTRSQWRVMANLGRFGKLTATEISHHGRLEKSVVSRAVFAMEKRGWLTRHAKAGDRRVELLSLTGDGQEIYMVLVHEAKAFDDELRSFIETAQVEGFVAVLRRLNDEAE---- ->tr|A0A1E5K837|A0A1E5K837_9MICC MarR family transcriptional regulator OS=Arthrobacter sp. D4 GN=A5N13_09045 PE=4 SV=1 -----------------------------------LSDFRLRERSFSVLTLACSGLEATQREIAEFLDLDLNQVAGLVDDLEHRGLVERVPGQRNRRSRAIVSTQEGRRIHNKIRAELDVCEQQQLARLCDDEVVHLKQLLRKALW------- ->tr|A0A0R1FVD3|A0A0R1FVD3_9LACO Uncharacterized protein OS=Lactobacillus kunkeei DSM 12361 = ATCC 700308 GN=FD43_GL000325 PE=4 SV=1 --------------------------------------SEISWAEARILMDVGYMKNPTPMKIAINLDLDKSYVSRVINKLNNLKYIEKKDTKKDKRTKLLYLTNTGKQVVEQLNINSDKQIQLIIDNLSNEEQESFYQSINTLNQL------ ->tr|K6SX39|K6SX39_9CLOT Transcriptional regulator OS=Clostridium sp. Maddingley MBC34-26 GN=A370_05447 PE=4 SV=1 ----------------------------WSSVFLDYS-----KNEILAMLLIYRKNKVNMSEVAEYINAPLNTATGVISRLEKKNIAERTRDNEDKRVVMITLTENGREFILEEKKQIEYYFKEVYKSLTKEEINAAMSIVNKVVTVLK---- ->tr|A0A0L6JVS5|A0A0L6JVS5_9FIRM Transcriptional regulator, MarR family OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_5096 PE=4 SV=1 ----------------------------IINIDLELS-----KSEIVLLLQLEKQGELMMSKVSDSLNVPMSTATGIVERLVKSSYVIRDKSETDRRIVVIKLTDKGKSLVSKIHTIALGYIDDICNELEPEEIQMIIKIFYKVIDVVE---- ->tr|A0A0M4G7W8|A0A0M4G7W8_9BACI Uncharacterized protein OS=Bacillus gobiensis GN=AM592_06060 PE=4 SV=1 ----------------------------IDETLKKVT-----RSELIALIILKQRGEATMSQLASEMGLQKSTLTNIRQRLTKHGLIQHYRDANDQRIIRISLTEDGEEFADRVLETMSRVLQKIKDALTSDELEQLINLLLKVAKVVQ---- ->tr|W7QEQ8|W7QEQ8_9ALTE MarR family transcriptional regulator OS=Catenovulum agarivorans DS-2 GN=DS2_04320 PE=4 SV=1 ------------------------------KAVFKQTGYEITP--EAyFLLNLIPESGIEQGALVKKTGKDKAAITRLLDWLSGKNWIIRRVVPDNKRKAIIKISPQGKEVLVALNKALSNISQPMMKGISKNEHMVLMNaikqlddNLL----------- ->tr|A0A1C0Y6W6|A0A1C0Y6W6_9BACL Uncharacterized protein OS=Caryophanon tenue GN=A6M13_05725 PE=4 SV=1 -----------------------------------CATRKMTSMQFLMLRYIHQSKSCTSMDIVKAWNVEKPTVSEHIRRLHDKGWVAITQGA-DRRVKNLSLTTEGIAVYEDIIIEVERLQQEVTAIFTEDELDVFTRFVAKLEQQ------ ->tr|A0A243INS8|A0A243INS8_BACTU Uncharacterized protein OS=Bacillus thuringiensis serovar yunnanensis GN=BK708_39455 PE=4 SV=1 -----------------------------------LTELELYSSQFVLLNALRRIGPCTQSDLSKYLSIEPAAISNIIRRLEKGDWISKTKGT-DRRKKIISLSTKAQKNTESLDKVDQDMLSQMYQGISLDKLQISLETLLQIEKN------ ->tr|W6TRA5|W6TRA5_9SPHI Uncharacterized protein OS=Pedobacter sp. V48 GN=N824_26720 PE=4 SV=1 ---------------------------------------KFTLPEVRVMYEIHHaKKVSAKA-ITELLDMDKSYLSRVLLSFEKKGLIEKTSDHADARIQVIALSATGAKEYEKLNKASDNQIADLMKRLNNEEIKELILHMGAIQNILSKIS- ->tr|U4V0H6|U4V0H6_9RHOB Transcriptional regulator OS=Rhodobacteraceae bacterium HIMB11 GN=HIMB11_01227 PE=4 SV=1 ---------------------------------------GLVRAEYILLACLSHYDELTARDVAQISMRPRNTISRAVHRMVAEQLIERRHNRVDKREASLTITKKGQRLHERIAAYLTQRQEDVFAGLNAQERQELSKLLRKTAL------- ->tr|A0A118E5D0|A0A118E5D0_BURVI MarR family transcriptional regulator OS=Burkholderia vietnamiensis GN=WJ03_29660 PE=4 SV=1 ---------------LQQFGRTYRA---FMSAFETHVGQPMP--RWRIMVALHTLDgQASQKKLVEVLRIDPGALTRQLKSLDALGWIERASDARDNRVTNVTLTAAGRAAFDACLPRRKAFLDRTVAQLPDDVLTALSGALAMLESRIAEV-- ->tr|R6K9W9|R6K9W9_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:248 GN=BN561_00696 PE=4 SV=1 -------------------GELIKRLNDILGTCANkelkSDDMTASQIKMliiisetknesITLKELEKHFGVAQATV-----------AGIVARLEKKAMIESFYEPDDKRVKHVKLTDKGRGVCKHAWANMVKKEEWFLSSLDDDEKEELWRLLQKIYDNMRRNE- ->tr|A0A069CSD7|A0A069CSD7_9LACT MarR family transcriptional regulator OS=Weissella oryzae SG25 GN=rmaE PE=4 SV=1 -------------------------QRQQYDQLS--QEYDISRTQARTLSYVAKNPGLNQKQIAEYLSVRGSSTSDLLKDLEADDYIERYASRgTKDRSKKIYVTAKGLKLIERLDKLFIDIDGKLIAGISKEDTVNLKRILSMMDNFL----- ->tr|A0A1V3Y594|A0A1V3Y594_LACGS MarR family transcriptional regulator OS=Lactobacillus gasseri GN=BXT97_04900 PE=4 SV=1 -------------------------ENLLINQRL--SSINLRMTHAHALRYIQKHPGCIQKEVAEYLFYQPASFTNVVKLLEKRQMIERRPDPKNGLKKQLFLLPAGKDVLDQVNQAFEEVNQ-LVGTVKSDTLTKLEEISNNLEKQV----- ->tr|A0A0S2HVI7|A0A0S2HVI7_9BACT Organic hydroperoxide resistance transcriptional regulator OS=bacterium L21-Spi-D4 GN=ohrR PE=4 SV=1 ---------------------------------------GISIPQLLCLQFLHESDNFQAthKAITRYLELNSSTVTGIINRLQKKGLVARLPKQQDKRTTYIALTSTGEQMLKNSPQLLHTRLSDKLDNVSAESIEVISDSLDKIIS------- ->tr|D4H7F2|D4H7F2_DENA2 Transcriptional regulator, MarR family OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_1179 PE=4 SV=1 ---------------------------------------NVTLPQMLSLYEISQHDSMNLTELTRSVNLNNSAITGIVDRLEAKGFVNRVKKAGDRRTIYLEITPAGKEYTALLTKILEDDCFFDEKKLGKENVNDIFQSLAKITN------- ->tr|K2N7Y6|K2N7Y6_9RHIZ MarR family transcriptional regulator OS=Nitratireductor pacificus pht-3B GN=NA2_05266 PE=4 SV=1 -------IYQLRDGLGFRMSRTARVMERHYEQL--LAEIGLSRLMWCVLVMVGSYgIAAPS-AMAEFLSVNRTAISRVLREMEKQGLVLRRQQDGDRRGRDIGLTELGQHKLEVFLPKATLTTEHFKSKLTEDEFEMLKTVLDKMME------- ->tr|A0A1X7EEW8|A0A1X7EEW8_9DELT DNA-binding transcriptional regulator, MarR family OS=Desulfovibrio sp. K3S GN=SAMN06295933_2862 PE=4 SV=1 ------------------------------------SALGITYCQVGFVMTALNHPGWNQEQLSHFLVVDKGSTARSVAKLIKLKFLYREENPQNRREKLVYPTEKAEEIREDLHKALQSANQLMMSNLREPEKVVLLEMMKRMIDTGRNSL- ->tr|M3TEE9|M3TEE9_9ACTN Putative MarR family transcriptional regulator OS=Gordonia malaquae NBRC 108250 GN=GM1_012_00290 PE=4 SV=1 ------------------------------------AANGLTFTEYSLLRMVDDRPGMNAAELASTAMIDKSTASRQLGALRDRGLLARAADGRSARGQRLELTDLARTTLSDIASASEAAISARLTDWPADDVATFAALLHRYNSS------ ->tr|A0A1C2BU11|A0A1C2BU11_9PORP Uncharacterized protein OS=Macellibacteroides sp. HH-ZS GN=A9168_10855 PE=4 SV=1 -------------------GMASLALSKALNAALIENNIDLPHSQFVVLRILYFHDGMSQLDIANMVSKDAAAIKRTVDNLENKGLAVRKQV--RTLKNSVCITDKGREFMPQVLKIADKIIEEALNSFSEESREQLFSMLKMIYQNIE---- ->tr|A0A0D6ZAX6|A0A0D6ZAX6_9BACI Uncharacterized protein OS=Bacillus subterraneus GN=UB32_09825 PE=4 SV=1 --------------------------------------EKITIPQFIVLQTISKEKRCNLKDIVNELGTTTGAVSLLIDKMTKLDYVLRERDTTDRRLIWISFTKKGAELYDQITQKRNEVLEHYFSKWTEEETKTFMNLLTKAF-------- ->tr|A0A081B7W7|A0A081B7W7_9RHIZ MarR family transcriptional regulator OS=Tepidicaulis marinus GN=M2A_0634 PE=4 SV=1 -------------------------------------------GHQRLIRQLLLKDGQTQTELATAMHIHKVSVGLYINDLVEMGLVERRRHPKDGRAYCIHLTEYLHRFRPEGERVFAEIHAHAIKGLPTEEYRMLLQAMEKI--------- ->tr|A0A0F7FXJ3|A0A0F7FXJ3_9ACTN Transcriptional regulator, MarR family protein OS=Streptomyces xiamenensis GN=SXIM_33160 PE=4 SV=1 -------------------------LNDRLLAEVAA-GTGVAASSFQVLWHLLAAPSRsaPMRELTETLGFSTAGTTKVVDRLAQQGLVDRRPSRTDRRVVYAVLTEEGAATATAAARAlAGALRRHLVAPLGPEGCAALLGALLTLEDAAA---- ->tr|A0A1F8S2V6|A0A1F8S2V6_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_69_14 GN=A2Z32_05235 PE=4 SV=1 -------------------------VSRRLDEELRA-EHNISFAEYDTLLTIAQAPGRriRMGQLAQEVLLSKSGVTRLIDRLVGDGLVERSACLADARGAEAVLTERGLSRLRAASRThLRGISEHFLAVVEPDDLDALERSMTAVVRQAG---- ->tr|A0A1Y6FHZ3|A0A1Y6FHZ3_9MICO DNA-binding transcriptional regulator, MarR family OS=Agreia sp. VKM Ac-1783 GN=SAMN06295943_3071 PE=4 SV=1 -------------------------LERRLGEQLR--PFGLTHGEYAILSILEANGPTgcRMTRLGELTQNPKTRLTQQVRRLEQAHLVSRAAVEEDARGVRVVLTDEGRRVLAAAAPGhSHVVRELVVGHIGEEDARVFARVLRDIENRLD---- ->tr|E6V159|E6V159_VARPE Transcriptional regulator, MarR family OS=Variovorax paradoxus (strain EPS) GN=Varpa_4922 PE=4 SV=1 -------------------------------------GFGITHREWELIAALRQIGEATPSAFAEHLQWDRVRTSRGLGSLSQKGLVERRRDAEDGRGVHVRLSPQGQQLFDDLFPRIARLDAELVAGIDDAQAGIFLQCLSRIEL------- ->tr|A0A1F5J6P5|A0A1F5J6P5_9BACT Uncharacterized protein OS=Candidatus Dadabacteria bacterium RIFCSPHIGHO2_12_FULL_53_21 GN=A3J42_03265 PE=4 SV=1 -----------------------------------------KSNQFIVLVAVAHLESPNFTKLADFVGIDQSTLARNLITVEKQKLVSVKTG-KNRREKLITLTKKGEHKIEKSFPLWKKAQGRLVGGIGAERWRDIQNELQDV--------- ->tr|A0A1C7G8E5|A0A1C7G8E5_9FIRM Uncharacterized protein OS=Lachnoclostridium sp. YL32 GN=A4V08_19600 PE=4 SV=1 ---------------FPNLGRCISLLDRLMRMYYdrGLADFEIGWGQQFYAEYIYDHPGATAQEMVEYIRIDKATLTKIIKRLSEIGYIEIVSDQTDKRVKHLYLTPRAIPA----VKRIKEIHqdfqSTLCSGISPQDMQLTEQTMEHMMENINK--- ->tr|A0A0J9E5E7|A0A0J9E5E7_9RHOB Uncharacterized protein OS=Candidatus Rhodobacter lobularis GN=AIOL_002884 PE=4 SV=1 --------------------------------------RGLSIQEWRTLLVCTRLKDDHLRAIARWGVLDATHVSRATASLETKGLVRRYADPKDVRRKRIAITQAGEALVAEIWPEAQSLDAHIRASLGEAEYAALRTALMQILDT------ ->tr|A0A1C3STN7|A0A1C3STN7_9LACT Transcription regulator HTH, MarR-type OS=Lactococcus piscium GN=LP2241_20032 PE=4 SV=1 ---------------FQWTYREMQKqYDTLF------DSFGLTESRFLILMFLKRANENmlLPSQISEKLGASRPTVSKLLKAMEQKGLVEKHESVKDGRSSYFKMTIMGGDTLKTFMPHNFEAVKIIFGQLSKADHDSLKRLLAAINLGTET--- ->tr|A0A1D9PGX1|A0A1D9PGX1_9BACI MarR family transcriptional regulator OS=Bacillus velezensis GN=BK055_03960 PE=4 SV=1 ---------------LFDMAKKMNHvMEHYF------SSHGLSEGKFKILMFLFDAPGRslSPTELAKKSNVTKATITGLIDGLARDGFVNRSRHTGDRRKISIELTKEGKEKLMLFLPGHFSKISGVMENFTAEEKAAFTKMLEVLFDKILL--- ->tr|A0A0G9HVX9|A0A0G9HVX9_9XANT Uncharacterized protein OS=Xanthomonas hyacinthi DSM 19077 GN=Y886_35530 PE=4 SV=1 -----------------------------------LKPYGMNDSDFRTLMMLYSSEDGSAtpGELCALAEQKPTNMTRIANALAKKDLISRSHATHDRRQVLLRITPAGRRFVNRMPPPMFPPLVENFACFSSAERKTFEKLLKKLALHI----- ->tr|X1AKS9|X1AKS9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_01616 PE=4 SV=1 ----ISKIINLTRNFNKSMRHKF------HHS---IHDSGFTLPQLSVISMLEKHGEQKVSELSLKMGLSDSTVSGILDRLEQKDIIKRERTKDDRRVVRISLTGKSQKFCNDFRQKREEYFTQLLKSLSEQEIKDIIKGLEILNRVLAN--- ->tr|G0V3Q0|G0V3Q0_9CLOT Transcriptional regulator, TrmB OS=Caloramator australicus RC3 GN=CAAU_0090 PE=4 SV=1 ----ALEILEVLTSINKKVKRasKF------SPP---FKCKNKSQSAMKVMFHIMNSPPMTLKELSSLVGLANSTVCGIIDELEMEGYVKRIQDKDDRRRVIIIPTEKAELEKRNIENKFKEFLEYVLKDISAEDFEIIIKGLKKLDEIIKN--- ->tr|A0A1H5YQH5|A0A1H5YQH5_9BACL DNA-binding transcriptional regulator, MarR family OS=Paenibacillus sp. UNC499MF GN=SAMN02799616_02353 PE=4 SV=1 ----CVKVGELLRVIDTKHAKIV------NQH---YSPHNLTAPSINILLLLDKEGAMRVSDIGAALNMVDSNVSAICSRLENMELVERFRTKEDQRVVKIQLSPAAEEKMKDIIANVRDFQELFVKNSSREELEEIVRGLSLLERLLDN--- ->tr|A0A1C6FMD0|A0A1C6FMD0_9FIRM Regulator of autolytic activity OS=uncultured Flavonifractor sp. GN=mgrA PE=4 SV=1 ----SGDILMRYLKVTQHMSRLF------REH---FGRLHLTFPQALVLTVLGEEGPMPISALAERTGSANSTVSGIVDRLEKLELARRERSGEDRRVIYVAATARYEQLRKKTETDVGGYFSSVMDTLTEREKDQIIAALSRLDEALLA--- ->tr|A0A1R1BYI6|A0A1R1BYI6_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL H7-0331 GN=BK127_16855 PE=4 SV=1 ----AMHISKSIHKLTRLYNATL------EKF---MKELNLTKPQGIIIGQI-YKEPKTIGQITEAVQLSYSTVSGIIDRLERDEWIQRVRDKTDRRVIWIQRTEKMEEIKNKVEFYHEQFFHTVLSDLDTDELDKIASSLDLLNSQLEK--- ->tr|A0A0D8CR60|A0A0D8CR60_9GAMM Uncharacterized protein OS=Thalassomonas actiniarum GN=SG35_23480 PE=4 SV=1 ------------------------------------LAFKPAPMQLRAMRRIWSTGGSTLLDIARTLNRDKSQVKRLIDELCEVELVKREPNPADKRSKILKLTNKGYDFFETIEKIEAVFSEQLTAGIPAKDLEAFFRVSDRLSDNLREL-- ->tr|A0A1V5LW65|A0A1V5LW65_9BACT Organic hydroperoxide resistance transcriptional regulator OS=bacterium ADurb.Bin425 GN=ohrR PE=4 SV=1 ------------------LGYRMKVLTLALSRRFseVLSPYEVTTVQWVALCRLWRQEGITTMEIGSHVDMVGGTLTGLLDRMEERGLVSRRVDEQDKRRILVFLTARGKELYQVLPPLALAITGDTTKGLKPSDIDFMKDFLQRMITA------ ->tr|A0A1B7LWD3|A0A1B7LWD3_9MICC Uncharacterized protein OS=Enteractinococcus helveticum GN=A6F49_15980 PE=4 SV=1 ------------------------------------ANIGISAVSMRALGYIERHGPQRISHMASYESISQPAMTSAVNRLADDGLVVREPDPADARAQLVELTDQGQRMLDEYRNQVATVLQPMLENFAAADYAVIEHA------------- ->tr|A0A1F1UIN1|A0A1F1UIN1_9MICO Uncharacterized protein OS=Brevibacterium sp. HMSC08F02 GN=HMPREF3172_05360 PE=4 SV=1 ------------------------------------THGDEGWSAWRALAVIDQSERTTVGLLGQLYGCSQPAATKIAARLTADGFITRRPDPDDARASLLEITDKGRQWLVSERTSAVQKMGSTVDDLTAEDVAALTRS------------- ->tr|A0A1C5YF95|A0A1C5YF95_9FIRM Uncharacterized HTH-type transcriptional regulator yusO OS=uncultured Roseburia sp. GN=yusO_1 PE=4 SV=1 ---------------------------HYLNHFMNLQKYDLTKNQWKALIIIANSSTLSMSQLAQRMNISREQASRTIAPLADRKLVERKINAENRRQIDISLSKEGRQLFNDLKSSTSNLICRSMDKLSEEEISEFKEA------------- ->tr|A0A1C5V069|A0A1C5V069_9FIRM Transcriptional repressor MprA OS=uncultured Blautia sp. GN=SAMEA3545264_02319 PE=4 SV=1 ---------------------------KVILNTVDFKDHGFTKTQLCILLSLTAKSPLTMSELAAYIASSKEQATRAVAPLVKAGYLERIQDEKNRKLVLVQLTLYGKEMMQIEEVKLKETMAAKINNLSPEDREAFAQA------------- ->tr|A0A1A0MHV1|A0A1A0MHV1_9MYCO Uncharacterized protein OS=Mycobacterium mucogenicum GN=A5642_25030 PE=4 SV=1 ---------------------------------LERVNISEAKLDVLMIFAAQLGQSedewtvrQTPSGIAEYFGITKASATGLIDWLENRKLVTRTRHATDRRSTPVRITPEGEKLVAEALPVFEQACGGLIDVLSERDRRDLQRILDKLWIHVK---- ->tr|A0A1F9WY92|A0A1F9WY92_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFOXYA2_FULL_39_19 GN=A2252_11185 PE=4 SV=1 ------------------------------------DDQELTFIQRNILHYLRRNPNKTPSDVAENFCIKKSSITRIIDLLEKNGYVVSINDKVDKRRTFLNLTKKAQDKVKNIDNVPLQKLGKMFSVLSSKEQKVLLKGCA----------- ->tr|T0R237|T0R237_9DELT MarR family protein OS=Bacteriovorax sp. BSW11_IV GN=M899_2441 PE=4 SV=1 ------------------LNRTTITLRTVLQNFFNKRDIDLTPEQWAIMGLvWNFQDELKSKTLSEHFFRDKSTVSRNLKKLEDKELIQFNPSLEDSREKIIKATTKSKSIQKKVYKTINDVLEIAEEGISDKDLEITLKTLAKMDDNLS---- ->tr|G2FMS4|G2FMS4_9FIRM MarR family protein OS=Desulfosporosinus sp. OT GN=DOT_0999 PE=4 SV=1 ----------------------------------EWSDLTF--KQFVYLDTILKMNKPTYSEIAKKFNITKPSVTAMVNKLIGLGYLERVQSVDDRRVYHISVGAKGRIMLAIEHNSVTGFAQQITSSLTEAEATTYIALTKKINAQY----- ->tr|A0A0A2TB26|A0A0A2TB26_9BACI Uncharacterized protein OS=Pontibacillus yanchengensis Y32 GN=N782_20340 PE=4 SV=1 ----------------------------------KEYGISP--TLESLLMVIIRLEHPTTTQLAEEMDISKSAVSQMITKLEDGDFVQKVVDPEDKRVQHLELGPKGKYYAQDLKRYEDYVHSLFAKSLNETEVDQVSQSFEKILQVM----- ->tr|K1Y578|K1Y578_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_77C00064G0001 PE=4 SV=1 ----------------------------------NFSNLTH--TQMHYLETISLLSNPNITELASYMELSKPTVKVAIDKLIEKELIFKIRSDEDRRSAHIHLAEKGKLINQMHDYAHKRIAEEFGNKLNKDEIEQLINILSKVLKDK----- ->tr|A0A1B8WPL3|A0A1B8WPL3_9BACI MarR family transcriptional regulator OS=Bacillus sp. FJAT-27264 GN=A8L34_03155 PE=4 SV=1 ------------------------IMDRVVKDMSEKTG--LSeEGDFGILVRLVDLGNgvLRQQELVDSMEWTKSRLSHHLTRMEQRGLVLRKPLD-TGNGVQVIITDSGKSAVDASRPIYAKAVRkYFLDQLSDQDTELITKLAERTDKMAS---- ->tr|A0A1S2I0G5|A0A1S2I0G5_9MICO Uncharacterized protein OS=Curtobacterium sp. MCBA15_012 GN=BIV00_12970 PE=4 SV=1 ------------------------VRQRVAEDIKAGSG--LSDQEFGILTRLVELGNgeLRQNELGALLRWDRTRLSHQLTRMENRGHVGREAV---DGGVLVRVTDAGAALVRAARPIHAEAVRkHLLHRVQGVDDATLLRTLEALAVDPG---- ->tr|E3J3N6|E3J3N6_FRASU Transcriptional regulator, MarR family OS=Frankia sp. (strain EuI1c) GN=FraEuI1c_1306 PE=4 SV=1 ------------------LLRLAALSRQHCADQLSSV--GISQHQHGILCCLQEYGPACQRDIAARLSIDSGDLVAFVDGLQKDELITRQRDERDRRRQILSLTPAGARMLRHIEDLLDASEPGPLEVLPEDQRQEFLAAATLVLA------- ->tr|A0A1Q4ZCY8|A0A1Q4ZCY8_9ACTN MarR family transcriptional regulator OS=Micromonospora sp. CB01531 GN=A6A27_38470 PE=4 SV=1 ------------------ISQTAVHARRLVSEAFAVS--SARGYHYRVLAALQEFGPASQAELGRRGRMDRSDVVAAVTELAREGFVERSADPADRRRNTVTITTAGIQQLQRLDRALDTAQDELLAPLSVAERRALVALLGKVLE------- ->tr|A0A0J1FLI3|A0A0J1FLI3_9FIRM Acetyltransferase YpeA OS=Desulfosporosinus acididurans GN=ypeA_1 PE=4 SV=1 -------------------------------------EFSLAEV--RVLYDIEHMEVCTAKKLIEELKIDPGYLSRIIKRFENDSLIYRVQSPEDGRLYYLFLTDKGKNTLSKLNDLSNDQIYNLISRLPERDKMSVVESMKTVENAFS---- ->tr|A0A1J1E523|A0A1J1E523_LYSEN MarR family transcriptional regulator OS=Lysobacter enzymogenes GN=LEN_1856 PE=4 SV=1 -------------------------------------PYTLTQA--RVLFELAQREPVAAREIGETLGLDAGYLSRIVQAFVDAGLVEKQRSEHDARSFALRLTGSGRAAFAVLDRRSHETTAAMLATLSPLDRERLLRAIAEAERALT---- ->tr|A0A222PAK9|A0A222PAK9_9FUSO Uncharacterized protein OS=Leptotrichia sp. oral taxon 498 GN=BCB68_08025 PE=4 SV=1 -------------------------------------NFSLNEY--RILNEINNLRDCTSKKICRNLYLESNFVNRTLRKFQKFNLVKKKLSLLDKRLYYFDLTKEGKNKLKNFNRMSDKKTKEIFSNLDIYDRERLVKDMSSIKMILD---- ->tr|B9JJ28|B9JJ28_AGRRK Transcriptional regulator protein OS=Agrobacterium radiobacter (strain K84 / ATCC BAA-868) GN=Arad_8715 PE=4 SV=1 ---------------------------------IREAGIPLDRALFPLLVLIERLGPIGVVDLADRVGRDHTTVSRQVAKLESLDLVVRQASAVDRRVREAIIAPKGKIMTDAVDGARDRIGDAILESWDVNDIDDLVRLMRKFADALN---- ->tr|A0A0R1SJL8|A0A0R1SJL8_9LACO Transcriptional regulator OS=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 GN=FC27_GL000428 PE=4 SV=1 ---------------------------------IRIAGVDLEATSLQAFITIGRMQPTNVSDLANILGKSHSSVSRQIDKLESKEIVETENDHSDSRVRSIRLSCKGNQIIESINAARLEALKSAFSTWEEKDKQSLLSDLKHLSKTVD---- ->tr|C1CUV9|C1CUV9_DEIDV Putative transcriptional regulator, MarR family OS=Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) GN=Deide_10800 P --------------------------------------T--SLTRCQILTTVGRDGTLTLAGLSRRLNLDKGWLSRTIDDLVHSGLIHKQPSTTDKRTIDLTLTPQGQHRVAALSSELNDQSGRVIDRLPVTERHNVLRALELLA-------- ->tr|A0A0R1RXW1|A0A0R1RXW1_9LACO Uncharacterized protein OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL001780 PE=4 SV=1 ----------------------------NIFRFINTESSDLTPLNSLIVCTVACHPGIAMSDLADQLGIAKSQLSRNVLTLEKLDLVERRHNTDNRRLVNVYANPAGNAMAQAQVLKVAQHLNGLLDKLEAPEQQRLDVLLSE---------- ->tr|A0A0R2I894|A0A0R2I894_9LACO Uncharacterized protein OS=Pediococcus inopinatus GN=IV83_GL000855 PE=4 SV=1 ----------------------------AISQNRFPDKFGLTRLQAITLRNVYRQSGITMTQLAQKIGITRPQLTRIIDTLEERGLVSRHHNDDNHRVINVLRTEKGKKVVKKHMDLIQSRIQRLVDTLDDEDQKALVTHLQG---------- ->tr|J6HFU2|J6HFU2_9FIRM Transcriptional regulator, MarR family OS=Peptostreptococcaceae bacterium OBRC8 GN=HMPREF1143_0393 PE=4 SV=1 -------------------VRLIKILNISIEKRVNndFKKMNLTMQQIKILLYLKERekNTveittqKDIQNLLGVTH---PTTISIIKSLEQKKFITSKHSEIDRRLKTLHLTENAYEMTQSIVKGKINFDNDLLRGIEKNELNACIKCLNKMYENINK--- ->tr|A0A173URV0|A0A173URV0_9FIRM Transcriptional regulator SlyA OS=Roseburia intestinalis GN=ERS852572_02280 PE=4 SV=1 -------------------GLRFSILDREFKRKLEerANRMGLTAVQLRVLGELSRAesMGaceinqKDLEKALAVTH---PTMTEIIKRLEKKKAVICTQSKVDARYKKINCADEYKNIHIELKKMDWEIFNKICAGIPEEDIQTFLKASEKMLENIEK--- ->tr|Q28Q22|Q28Q22_JANSC Transcriptional regulator, MarR family OS=Jannaschia sp. (strain CCS1) GN=Jann_2273 PE=4 SV=1 -----------------------------------LTPLKLDLYSSRIIVALAERGPLKVGQLVDLMALPQSTMSHQLKRMEKDGYVQRTRSDTDNRTVVITLTDEGETVSETCNRWSDQVLNSVSEELSDSEIEALSALLQRVFKSLPQ--- ->tr|A0A1M3MMY8|A0A1M3MMY8_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 63-22 GN=BGP07_01240 PE=4 SV=1 -----------------------------------FREDGLSIPAARTMVSLLEAGgEAPVGSVSEATSIDLSTTSHILRRLEKQGYVKRERDPEDNRVVIAFLTIEGKVVAKRCRQASLDHEAILTKSMAPADVATFKRLLVEAFDNAKD--- ->tr|A0A0Q9KC00|A0A0Q9KC00_9MICO Uncharacterized protein OS=Janibacter sp. Soil728 GN=ASG73_00735 PE=4 SV=1 -----------------------------SAMWSRVIGPQLTGPQFAVLDVLDAYDGSDQASVGHAAALDASTMVDVARRLERRSLIVRTRSPIDARRKVVQITSLGESELFRVRERRVQLEQRLFAHNPR-RKDEILAELNDL--------- ->tr|A0A0M2LL26|A0A0M2LL26_9MICO Uncharacterized protein OS=Leucobacter sp. Ag1 GN=XM48_16020 PE=4 SV=1 -----------------------------TASWGRAVSAEVTSTQFGVLTFLERFPGESQKDIGAHLSMDKSNMTDVANRLTRRGYVRVLKDPRDQRRNVLVLTPEGRSLLAELRPRVDALRADTFAEFSGGELLEFLGGMDRL--------- ->tr|A0A0L8EWG8|A0A0L8EWG8_9CLOT MarR family transcriptional regulator OS=Clostridium sp. DMHC 10 GN=AGR56_17360 PE=4 SV=1 ---------------------------------------GFTTTQCYTLLEISKFGSLSMNEISEKMNLNSSTMTRILDKLVRDEYISRSKDDNDKRIVIVSLREKGIEAASKLSDSVKAYYKKIIENIPEGQVEEILKSVNILQKAFEKAN- ->tr|A0A0Q4EH42|A0A0Q4EH42_9FLAO MarR family transcriptional regulator OS=Chryseobacterium sp. Leaf201 GN=ASE55_02240 PE=4 SV=1 ---------------------------------------DSTAVQALTLLKIDPKEGTRSTNLGPKMAIEPTSLTRIIKLLEDNGYIYKEKTTTDKREVIIKLTDKGLNSRNMSKEVVVNFNKRIMEKIAPEKLETFKEVMTEIMKIAVDLN- ->tr|Q97LD5|Q97LD5_CLOAB Transcriptional regulator, MarR/EmrR family OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VK ---------------------------------------EISVVQVHAIFEIGKLREVSTNEFSKILYLDKNTVNKIVNNLVDEKFVLRHIHPENTRHVILKLTENGQKIYENIRDDFKLYCKRILDNLPEKSRESITKDFEILLKSMEDNA- ->tr|F9DXA6|F9DXA6_9BACL MarR family transcriptional regulator OS=Sporosarcina newyorkensis 2681 GN=HMPREF9372_3437 PE=4 SV=1 ------------------LRTVSGSLTQLYNRLLKPSGLKI--TQYYMLGNIFCFPNISISKLGELMLLDQTTVTRNLNILKESAYVTIMRDEYDSRTKIVSITETGIEKLNEAEPILSHVQNIVEESFGKKEYSDLVNKLEGLQK------- ->tr|A0A1D7UU03|A0A1D7UU03_9LEPT MarR family transcriptional regulator OS=Leptospira alstonii GN=A0128_03520 PE=4 SV=1 ------------------LKRASRAIAQYFDHVLDPVGLTS--ARFNILMTLGTTEGMELAPMADLLVLDRTTLLRNLEPLETLGYIKDIPSE-NKRARKVALTEKGWDALRLAYPVWKVAHDHVVQNLGVPEWKSIIKGLRTISK------- ->tr|A0A231P5P3|A0A231P5P3_9DELT Uncharacterized protein OS=Desulfovibrio sp. MES5 GN=BCS36_04935 PE=4 SV=1 ------------------VRKADRLLSQMYGRYFAKSGMRG--TQFALLRAIAAMPEPFITEIGRILGMDQTTVTRNVEKLEKAGLVETGPNPGDTRKKMVRLSASGKASLAVAEPCWAEAQQALLDGLGEDEARELLRLLAKVSA------- ->tr|A0A0N7M3F6|A0A0N7M3F6_9RHOB Homoprotocatechuate degradation operon regulator, HpaR OS=Phaeobacter sp. CECT 5382 GN=PH5382_02713 PE=4 SV=1 -------------------------------ARLKKHG--VQIEAWRVMELLDGDARLTMGELAKAALINPPTLSKLVDRMVSDGLVHRQIADEDHRQINLLLTDLGRLRMLQIREDVVQQDLQLRDQMAQEDSKQLLELLSR---------- ->tr|V6F114|V6F114_9PROT Putative Multiple antibiotic resistance protein marR OS=Magnetospirillum gryphiswaldense MSR-1 v2 GN=MGMSRv2__0761 PE=4 SV=1 -------ISPLTAHLGYWLRLV---SNHVSHAFAgKLEGRGVTVAEWVLLREVHDHRSISPSRLADRLSLTRGAVSKLADRLIDKGLLGREPSPEDGRAHSLALTADGRTLVPELAGLADSNDAEFFGDLTPDDRATMERVLKSVV-------- ->tr|A0A160PF47|A0A160PF47_9RHIZ TrmB family transcriptional regulator OS=Methylobacterium populi GN=MPPM_3194 PE=4 SV=1 -------SAEPVDPLRVWFRfiRL---SRRVTAAVAgELREIGLSIPQFDVLSTLSEREGLTQQELAARLYVTKGNVSGLIDRLVEAGLVERRAIPGDRRSHALHLTGAGSEIAARGIAAQAAYVARTLGRLDEADLRAFEELVVKWR-------- ->tr|A0A0W0YCV6|A0A0W0YCV6_9GAMM Transcriptional regulator, MarR family OS=Legionella santicrucis GN=Lsan_3442 PE=4 SV=1 -------VSPLKSHIGYHMRVV---SNEVSQAFAkKLSKYDVAVAEWVILREMYETKkSTSPSAVAEMVGLTRGAVSKLIERLLNKDLVTRTESSNDRRFQQIKLTSKAIQLVPSLADSADQNDESFFGVLSDNEKGTLIKILKKLS-------- ->tr|A0A1J0A647|A0A1J0A647_9ENTE Uncharacterized protein OS=Vagococcus teuberi GN=BHY08_05810 PE=4 SV=1 --------------------------------------LNITYEGYYCLLGLTQVPSMTMTDIATDFYFGKQQTTRIISQLVSHGLVEKTVSPLDKRITNVSISEKGMSYLKRNPFDTTDLGEDLNEKLTKEEMEELNHALDVLLKI------ ->tr|U2CT75|U2CT75_9CLOT Transcriptional regulator, MarR family OS=Clostridium sp. KLE 1755 GN=HMPREF1548_02192 PE=4 SV=1 --------------ILIGLHRVSNEIDRRTTRIVKCYG--LSMGQFAVLEALFHKGDLTIGQVQEKILSTSGTIPVIIKNLEKRGLLIRLPDAGDKRKCILHITEQGSSLIQQVYPENEAMIIESMHNWTNDEKCELLKLLKKFGGGT----- ->tr|A0A1X7MVH9|A0A1X7MVH9_9LACT Transcriptional regulator, MarR family OS=Carnobacterium iners GN=SAMN04488700_0815 PE=4 SV=1 --------------LMVVFGKMARTLQENLSKNLEELG--MPFSLYPILAYLNEVEKAKTQKLGEVAVISSGTITHTVNKLLKLNYVEKIQDEQDKRVFWIQITKEGKKRFMEVHLKHMEYLDELLKEFSEEDKTALIELMKLFGKGI----- ->tr|A0A0D2W283|A0A0D2W283_9PROT MarR family transcriptional regulator OS=Skermanella aerolata KACC 11604 GN=N826_39745 PE=4 SV=1 ----------------------------------------------------GANPGLRPSVLAHFILKDRSAMGKLLEQMERTGLLEQKVSVTERRARELYLTPKGRALAQQVREVARRQSDDFFSVLTDEEQDALMRILRKVYESY----- ->tr|A4AV27|A4AV27_MARSH Probable transcriptional regulator OS=Maribacter sp. (strain HTCC2170 / KCCM 42371) GN=FB2170_00245 PE=4 SV=1 -------------------------ADGYMRNCLKEFG--ITENQMTILFALSKLGKVEQGKIGEALVLERSTVSRNVKLLQKYKLVRRTT----AYRPEIELTNEGIDLVNKLIPHWEEVMDSLVDMMGDYGTVPLEKLEQRL--------- ->tr|A0A246FXK2|A0A246FXK2_9PSED MarR family transcriptional regulator OS=Pseudomonas sp. K2I15 GN=CEC48_18065 PE=4 SV=1 -------------------------MAQIYDEAFVPFG--LKATQYSLLNHIANGDAPKMRDLAQSLVMDLSALGHTLKPLVRDGLVVLQVDELDRRSRRVLLTDAGQRKFEEARVVSKQMAVRFDEVFGAEAACELRRSMDFI--------- ->tr|D9Y1E8|D9Y1E8_9ACTN MarR family transcriptional regulator OS=Streptomyces griseoflavus Tu4000 GN=SSRG_02836 PE=4 SV=1 ------------------------------ALLTERHQITFSA--FEVFCRLRESEePQAMRSLARLlVSVSPTRASRIVQEHIDAGHLARAADQTDGRISLISFTDAGRRYADAASRTFEQAIDQHFAGvLDEEDMNALLRIWEKLRQT------ ->tr|A0A0T1Q6P2|A0A0T1Q6P2_9ACTN MarR family transcriptional regulator OS=Streptomyces sp. Root431 GN=ASC82_13110 PE=4 SV=1 ------------------------------SDVQRDGRIPLTW--YDVLLELRGAGeqGLRMQEVAERVVLSRTRVSRLVDEMARSGLVTKQPDSTDKRVTWAVITDEGRSALRATAPAYMRGIREHFGRyLTDEEATVITTALLRVAHS------ ->tr|A0A0P6RB12|A0A0P6RB12_9RHOB MarR family transcriptional regulator OS=Phaeobacter sp. 11ANDIMAR09 GN=AN476_09850 PE=4 SV=1 ------------------------------GEFSAVHGISVNE--FLLLLHIKRSAsnRLSRVDLAKRMHVSASTITRMAAPMEKVGLVGREVDQRDARLIFVVATDAGQEKLSEALATFSKRASYLFSDrWEVDEVDQFASMLGRLIGG------ ->tr|A0A1V2NVG4|A0A1V2NVG4_9ACTN MarR family transcriptional regulator OS=Kribbella sp. ALI-6-A GN=BWI15_31785 PE=4 SV=1 ------------------------------RHSLKRSGLQMAM--FELLLRLARSHgeKQRLTSLARELTVTTGGITRLVDRAENLGLVRREPCPDDARGSFAVLTEEGKRRLREALPDHLLEIDSLWTSqLADERELVLG-RLRRVRDN------ ->tr|A0A1Y5SNJ1|A0A1Y5SNJ1_9RHOB MarR family protein OS=Tropicibacter litoreus R37 GN=TRL7639_02239 PE=4 SV=1 ------------------------------RALVMAGLPKLNW--YDVLWELEQHPdGLRPVRLEERLLFDQSSFSRQVMRMAEEGLLTREPAADDKRGKVLRITAKGRDMRARMWVIYRPHIDAGMQSaIEAGGLEDVEAASRKR--------- ->tr|A0A1I6S5X6|A0A1I6S5X6_9BACL DNA-binding transcriptional regulator, MarR family OS=Marininema halotolerans GN=SAMN05444972_106167 PE=4 SV=1 ------MTHDTIQA-FQHVVHKLRrGIQQQLEE-------NWGVADFVFLHQLHTQGPSKGSDLSSELNVTNSHVTQHVNRMVKKGWISRHRSTDDKRIVELAITPAGTEVYNEMVKRRFQYFQQLFHTLSDEELDSLLHLLQKLID------- ->tr|A0A1G6SYK6|A0A1G6SYK6_9BACI DNA-binding transcriptional regulator, MarR family OS=Bacillus aryabhattai B8W22 GN=SAMN04487777_10380 PE=4 SV=1 ------LIQDVVST-MRNQTKKMQmSVIPTLKS-------YIPLNEFLALHMLYKEGNHIVSEIAEHMHISNSSMTCISDRLMEREFVTRVRSQKDRRVVYLSITDKGKAFAEEMEKVLTKEYGEKLSHFTDEELQTFLRLLNKMDI------- ->tr|U1N2M3|U1N2M3_9BACL MarR family transcriptional regulator OS=Exiguobacterium chiriqhucha RW-2 GN=M467_06175 PE=4 SV=1 ------LVADAERG-IRMNYRGVKkNLRSMFSQ-------YLTRNEFFILRSLCQNSPQIASALSNEFQFSASMITALADELTKKGLISRERSERDRRVVELQATEEGRALFETLEDMKIEYLMDVFTDFSDDELILLSRLLDRMDA------- ->tr|A0A136WCM8|A0A136WCM8_9FIRM Transcriptional repressor MprA OS=[Clostridium] neopropionicum GN=mprA_3 PE=4 SV=1 ---------------------------------------DLTLRQLMLLIAithLNPQE-TTIVNIASALGTSKQNINRLVNYMVKSGYLSRKYGQIDKRNVNIEITNKGLSVMQKNTINSNKYFLELFKNFSKKEIKALHQTLKKLA-------- ->tr|A0A178KTE0|A0A178KTE0_ACHLA Uncharacterized protein OS=Acholeplasma laidlawii GN=A2I99_02320 PE=4 SV=1 ------------------------------------ELESLSMQQAAIVKYLIHHKDKdlNSKDLEQAFSMRGSTCSRMLKAMEQNDMVVRIDDKEDSRKKIIKPTEKSIQIIRNIKSKFDEMENRIKDNISKEELEVFFRVIDQIKQNIT---- ->tr|A0A1F1GJZ0|A0A1F1GJZ0_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC078H07 GN=HMPREF2875_07455 PE=4 SV=1 -----------------------------------LDELGITYQQYLMLMILWDSeEPVTLESMEKRLQPESGTFEGLVKGLEESGLATVEDG-------KVIITQKGSDLEPRAVCIPETILNEYrKSGVDLVEF---RESLEIVREAG----- ->tr|U7V807|U7V807_9FUSO Transcriptional regulator, MarR family OS=Cetobacterium somerae ATCC BAA-474 GN=HMPREF0202_02397 PE=4 SV=1 ----------------------------------NLKIFNLESSQGIILLKIKELKKITPTQLVDLGVIEKPAISKTLKKLEGLGYIIKSQSNQDARSFYVSLTKDGERIASHVEEFLDKLDKKFHTILTDDNIQEIKNVLDYLE-------- ->tr|A8TJ10|A8TJ10_9PROT Uncharacterized protein OS=alpha proteobacterium BAL199 GN=BAL199_16243 PE=4 SV=1 --------------------------------------YEIdlTHRAIRVLQFISHHEkAPGLDEITKFLGSAPSTASELIKRLQNKGLVVRRRSSQDERTIEIELTGSGRAALTEHTSLNPRKLQNGLQALGDLEQEYLIGFIKKVTEAI----- ->tr|D1Y2T5|D1Y2T5_9BACT Transcriptional regulator, MarR family OS=Pyramidobacter piscolens W5455 GN=HMPREF7215_2172 PE=4 SV=1 --------------------------------------GRLSAPQLRTICVIGRNEDIRMKDIADRMELTTGTVTVMIDRLQVMGLVERCRNENDRRSYKILLSERGRAYYEEHRKRQKELVRKLALKISDSDREVCERVLENFMHCI----- ->tr|A0A1V5HLA8|A0A1V5HLA8_9BACT DNA-binding transcriptional repressor MarR OS=Tenericutes bacterium ADurb.BinA124 GN=BWY97_01184 PE=4 SV=1 --------------------------------------RGIklSMKEVHILETVRNTPVPTMSAVARKLRITTGTLTASIDRLVRKKYVRRGQEEKDRRKVIIELTEPAFAVLKIHDEFHNEMIEAIFADMKIDEDEILLKSLENISNYF----- ->tr|A0A196NK31|A0A196NK31_9RHOB Uncharacterized protein OS=Sulfitobacter sp. EhC04 GN=A8B82_04975 PE=4 SV=1 -------------------------------DFRARLGDeALHPGYFTILTLIVRNPHISQTQIGTASARDKSSVTKALRWMEDEGLIVRLRSASDRRIHLSVATEKGIRQQALMEAKAIGHLQSLNDAIGSERYATFIATLKDLIR------- ->tr|A0A1F6TE13|A0A1F6TE13_9PROT Uncharacterized protein OS=Candidatus Muproteobacteria bacterium RBG_16_65_31 GN=A2V92_00925 PE=4 SV=1 -------------------------------DLARLPSDaGMTPGEFSLVTVLGANPGIDSVTLARVYRLDKATLSLTLKRLTQRGLIWSERRSEDRRYVALQLTPAGRGALRRATRRIEKQERIMDSVLEAGEKERLLELLGRISR------- ->tr|A0A0Q8QXF3|A0A0Q8QXF3_9SPHN Uncharacterized protein OS=Sphingomonas sp. Root710 GN=ASE00_07330 PE=4 SV=1 -------------------------------LFLEVSSdIDVTPVQYAALQAIRDNPDNDQRLIGGLIAVDRTTINVVSLRLEQKGWIVRHVIG--GRRLHLELTQAGRQVLIDMAKVIPAHAERILAPLEPAQRDSFMAMLKTlveQNNDLSRA-- ->tr|A0A0Q4B0P1|A0A0Q4B0P1_9EURY Uncharacterized protein OS=Methanomassiliicoccales archaeon RumEn M2 GN=AOA81_05385 PE=4 SV=1 -----------------DQHIAPRVIKQYLDSRMTarLESLGLQGSQGPYLLAIARNPGASLKEIAAHLMVDKSITTRTVGTLIDMGLVRNESA--DARRYSLVLTGEGDNAVERIEETFSEIWDALLCDLTEEEQRAFESACAKIKAR------ ->tr|A0A1S2JDM2|A0A1S2JDM2_9MICO MarR family transcriptional regulator OS=Curtobacterium sp. MMLR14_014 GN=BIV02_01250 PE=4 SV=1 -----------------ALGHAVKRAQYRNHRTMDaaLRDLGVTLVQWDALRAIDRMPRASGHDLAVATFQSDQAFGTLANRMLDRGLITRTAG--RGRRIEHAITEDGRRVLDEGHRIAEGVLDSLFAPLDEQRRAALLQLLTTLTDA------ ->tr|A0A1Q4W828|A0A1Q4W828_9ACTN Uncharacterized protein OS=Streptomyces sp. CB02923 GN=A6A06_37520 PE=4 SV=1 -----------------EIGALSRIIRHHFADRIEqvIHPLGLTLGQWTVLRELKRTPGASASELARAAVHTPQAVSRLVRTLQEEGLVERSPA--RGRMMDNHLTAKGHKVMDETFLQIEARLAPVLEKFGRADTEEFRRLSHLLIEA------ ->tr|A0A1A0JHH3|A0A1A0JHH3_9MICC MarR family transcriptional regulator OS=Kocuria sp. ICS0012 GN=A5728_08670 PE=4 SV=1 -----------------------------------HRE--LSMVHTNILSYLACVPGRRAKDIVAESGLGASGMSRHLSALEHLGYVTRTRDLEDGRAQIVEITAEGRKALEANLRADAETLVARLGDLGEDEAERTRVDLNRLTELFLT--- ->tr|A0A0G8B2J0|A0A0G8B2J0_SERMA Uncharacterized protein OS=Serratia marcescens GN=AAY84_23835 PE=4 SV=1 -----------------------------------NHG--LTLSKARVLKAIEEHEACNATDVMTVLSYSCRSVTEALESLEAAGLITRHKAPGNRKVKIITLTGQGKERLHLAMQIRNDILTALLSCLEGSELVLFSDIINKIWLNHGK--- ->tr|A0A1Q6WWH2|A0A1Q6WWH2_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_2_20CM_69_8 GN=AUH12_04105 PE=4 SV=1 -----------------------------------LGPKHLSLSHMRALGFLDATPDAHLSAVAGYVGLALPSTSSLVDGLARRGLVVRLATpPHDRRRLRLRLTGAGKGALRTGLAAARAALDARFGGLSPGERALIARAMARLRPLLT---- ->tr|U2KYH7|U2KYH7_9FIRM Uncharacterized protein OS=Peptostreptococcaceae bacterium oral taxon 113 str. W5053 GN=HMPREF1987_01486 PE=4 SV=1 ----------------------------------------------------KYPEGLTSAMLSKISDKDKSDVSRSLNAMMKSNLVEKHSVHQKGYAGIFLLTDEGKKVAYEIIKKVNFAVKMANENLSEEKRVVFYEVLEIFIDNMTKIV- ->tr|A0A0Q8PBT4|A0A0Q8PBT4_9BURK Uncharacterized protein OS=Noviherbaspirillum sp. Root189 GN=ASE07_08640 PE=4 SV=1 --------------------------------------EGINLPEWLVIYTIALYPDIGPSRIGHFTGLHKTTISRVLSQLRDKGYIEQCVDPNDGRGKILSLTSAGKKIFVRRSGWAREWSTLLTSGLSAADRRALARMLDVVIDNSR---- ->tr|A0A0Q5ZEK0|A0A0Q5ZEK0_9BURK Uncharacterized protein OS=Ramlibacter sp. Leaf400 GN=ASG30_04995 PE=4 SV=1 --------------------------------------LGLTSRQWRVLVILNRLGTSPSGEVARMANFDHSQVSRVAFELAEKGLITQASDPVDRRKQILALTPAAVECLRDGVPVSLEREARLRSRLSPADYDTFIRALGALEEEAQ---- ->tr|S6GNN7|S6GNN7_9GAMM Putative OhrR transcriptional regulator, MarR/EmrR family protein OS=Osedax symbiont Rs2 GN=OFPI_30650 PE=4 SV=1 -----------------------------------LEALNLTYPQYVVMMALWEEDGITVQVLLEKTAVNGGAMSLILKKMIDKKLLTVTPSEEDKRKKLIHLLPTGQQLQDQAAEVPT-KIQCSFPNIEKADLHQLIGLLDKVCLDLADN-- ->tr|A0A178NDY2|A0A178NDY2_STALE Uncharacterized protein OS=Staphylococcus lentus GN=AXY34_11690 PE=4 SV=1 -------------------------FHYLCKDVAQSHGISLKLA--NLLEIIYEQDGITLNNLCRKVDEDKGNLSRLVNDLMKDSYVIKKQSERDKRIYYIYITEYGKEAILNLKQVCIHNMDSLLSILSEEEQNHFIKALTKLDNHVY---- ->tr|A0A1M6G1X7|A0A1M6G1X7_DESDE DNA-binding transcriptional regulator, MarR family OS=Desulfovibrio desulfuricans GN=SAMN05660830_01444 PE=4 SV=1 --------------------------------QLSVHGINFTE--FMILQSLENAAENTMRriELANAVNLTASGVTRVLHPMERIHLIEKRSNPRDARISLVKLTSAGKTIYADALITVESCAESLMAPLTSNQIETLTGLIKKLS-------- ->tr|W9DPV6|W9DPV6_METTI Transcriptional regulator OS=Methanolobus tindarius DSM 2278 GN=MettiDRAFT_0779 PE=4 SV=1 ----------------------------------------FNTLPNKTIRLIHFKKEINPSRLGIILGVGKSTITSTIDTLEKNGLVVRNNDPDDMRKQLISLTDAGEDYHFELMDMITERVSSISDsyGMSESDlveyydhLSQMVSILNKYIFET----- ->tr|T0D2B4|T0D2B4_ALIAG Uncharacterized protein OS=Alicyclobacillus acidoterrestris (strain ATCC 49025 / DSM 3922 / CIP 106132 / NCIMB 13137 / GD3B) GN ---------------------------------------LPSCNQLLVLKELDEVERMRLTDLSAALKLSPSTITGICDVLEQKGYIRRDRDLIDRRIVYVSLTAHGRTCLRSTRDSMIARLGSVAHTFK---egdLETAVAVLNAINRSL----- ->tr|A0A1Q9HD89|A0A1Q9HD89_9VIBR MarR family transcriptional regulator OS=Vibrio ponticus GN=BIY21_03305 PE=4 SV=1 --------------------------------------------EFDYLKVIQQYpQGVRITDLAQELCVSKPSASNMVTRLAKKNLVGTIACSEDARAKRVVLTDWVIENMSFERVVYQQIATDLNAQLSKQEAKQLVQLLNKALKK------ ->tr|A0A1N6RQR1|A0A1N6RQR1_9RHIZ Transcriptional regulator, MarR family OS=Rhizobium sp. RU33A GN=SAMN05880561_102688 PE=4 SV=1 --------------------------------------------ELDYLYLVIAAeKPLRLADLADQMRVSRASASVMVRKLHLAGYLDKLSDSADGRSVLLAPTAKCSALIAEEKSIYAETADRISRALTPDELEDLDRLLKKARGS------ ->tr|A0A1R4B8Q9|A0A1R4B8Q9_9VIBR Uncharacterized protein OS=Vibrio palustris GN=VPAL9027_03350 PE=4 SV=1 --------------------------------------------DYRYLDAVLIAdCACSVDYLATQVEGDIQSTQADIDTLCEKHYLI------MSELGRVSITELGKQKLANDRRVHALMALEMTASMSDEEAHLLDSVLHRS--------- ->tr|R7MQH0|R7MQH0_9FIRM Transcriptional regulator MarR family OS=Ruminococcus sp. CAG:624 GN=BN739_00205 PE=4 SV=1 ---------------------------------------ELHFGQFAVMNYIYDHDGCTQADLAENLKVTPASIATSTKRLQKAEMITKRIDEDNLRCKHLSVTDKGKAEIVQSRRLFDDYDSRLFSDFTDEELSVFNQCLIRLIIKMSE--- ->tr|A0A0Q8DMP9|A0A0Q8DMP9_9ACTN MarR family transcriptional regulator OS=Nocardioides sp. Root614 GN=ASD81_15585 PE=4 SV=1 -----DVVRELESEVGVLIRRIRRVI----GERARAVHPELLPASYLMLAYVRDHEPIRASAMCAVFDIDKGAISRQVQHLIDLGLVDKQPDPEDGRATLLSISTEGEQRLEAVAVERRELLAERLADWSADELTAFSGSLRRYND------- ->tr|A0A0D8FSY4|A0A0D8FSY4_9ACTN MarR family protein OS=Ferrimicrobium acidiphilum DSM 19497 GN=FEAC_18720 PE=4 SV=1 -----AFLKEIEdgiRSMIRWSRRHSSLL----A---HDLYQGLDLTALTILSALADHPGSRLTNIAEWLKLDLSNASRQTSLLESAQLIERTTDPNDRRSTLLSLSPEGRKVLDKARSDSTNFMHRIYQDWETVELAQFASMITRTID------- ->tr|A0A0Q5BYA2|A0A0Q5BYA2_9MICO Uncharacterized protein OS=Rathayibacter sp. Leaf299 GN=ASF48_03720 PE=4 SV=1 -----RALAEVEEQITALAVQVRSAV----RDAAAAIDPSLPPFGLRLLRMLERCGPVHASVAAERLGVDRSAISRQVRQLAELDMVEMTVDPDDGRARFLALTALGRERMAHLGGEQRQRMHRALRTWPEEDLLAFAGYLERLTT------- ->tr|A0A101KYI7|A0A101KYI7_9MICC Uncharacterized protein OS=Arthrobacter sp. EpRS66 GN=AQ436_05840 PE=4 SV=1 -----DRYSLAEQELFSLIAVTARFK----RELAHRLNGQLTPGYLPVLGLILRNGRITQSEICEKLLVDKATLSRMISKLEQLDLVVREVNAEDRRASDLLPTDYAKERWHSGFEQWRKELRSRMSNWADDDLDTLVELLGRLNL------- ->tr|A0A126Z964|A0A126Z964_9MICO Uncharacterized protein OS=Frondihabitans sp. PAMC 28766 GN=AX769_19940 PE=4 SV=1 -------MEAVYMQMETISRRAVARN----R----RTSAPLTVVQHTLLTFIASTRDCRAIDIAAALRLNRSTISRQVGDLVELGLVAAGASDAharehedagsggPGRGQILALSARGSELLQRSLEANHHELARRLADWTDADIDVLASGLERFNA------- ->tr|A0A1F1U9J1|A0A1F1U9J1_9MICC Uncharacterized protein OS=Arthrobacter sp. HMSC08H08 GN=HMPREF3175_07580 PE=4 SV=1 -----EQLRSLTREYRILLAAARRSF----REQAAALDASLQPFDGVVASALYRRfmetgsctpdAGMTVTELSEVVDADKSMVSRAIKRLETAELLVRTADPKDARSYLLVLSDSARARFKDYVMKRQQESAVMFEDWSIEEVSRLAALLKKLND------- ->tr|A0A1R4JWE6|A0A1R4JWE6_9MICO Transcriptional regulator, MarR family OS=Mycetocola reblochoni REB411 GN=FM119_10000 PE=4 SV=1 -----EQITALESALLGIVTEAKRTI----HARAERIAPDMQRGTFTLFTQIARLEPISAGSLAELLSLDRSVVSRSAKTLVEAGLIERHPNPSDGRGAVFSASARGRAMLDEARSAESARLRTEMGNWSAADVTRLTELLSRLAA------- ->tr|A0A1Q3Q9G9|A0A1Q3Q9G9_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 69-20 GN=BGO26_02395 PE=4 SV=1 -----PPDVRGRRPLSSVLRH---AE----MLFVAEFEERIAASdfadlslahAANVLRFLYR-GPQRASQFIGSCGVSKQAVSLQIAQLEKRGYITSAPDPQDQRARILALTERGEAAEAE----VQRIFVAIEKTWTkhlgAEDAKALRRILEKLP-------- ->tr|A0A1S7S450|A0A1S7S450_9RHIZ Transcriptional regulator, MarR family OS=Agrobacterium genomosp. 7 str. Zutra 3/1 GN=AGR7C_pAt0189 PE=4 SV=1 -----RHLKELGHELNALLAASRAIT----SASAERFHPQIQPAAYQIAMVLSMLGAARGSQLSQLLETDKSAISRLLKSLCDFGLAEPVTDPDDRRSTIYRLTQEGQSRVEASIEVKIGAFYSRTEGWSDAELSQLTELLRKFNR------- ->tr|A0A1Y3LXM2|A0A1Y3LXM2_9MICC Uncharacterized protein OS=Arthrobacter agilis GN=B8W74_06590 PE=4 SV=1 -----TVLGALEESAAAMCRNEQRVC----WTLARGVSAAMEPGAYSVLAAARRLGPCRVTDLAVTLGMSASAISGHVAALAGLGFVGRVEAVEDERSRRVTLTDDGRRRVDGARTGRRTYFRAQLRGWPTVEIVELADLLARFNE------- ->tr|A0A081JIB7|A0A081JIB7_STRMC MarR family transcriptional regulator OS=Streptococcus macedonicus GN=FD61_04085 PE=4 SV=1 -----------------------------------LKPYNITIMQSWVLMFLKRTENcYTFKELEKQFEVSQPTMAGILARLDQKNMIITSKDEKDKRIKKVEISDEGRSLINRLGEHLDDSERAIVGDFSKDEQEMFHLLLERAYYNVV---- ->tr|G5KD27|G5KD27_9STRE B-block binding subunit of TFIIIC OS=Streptococcus urinalis 2285-97 GN=STRUR_0546 PE=4 SV=1 -----------------------------------LKHYDLTPSQFKILRYVNHFKEKKirQIDIEHTFNMSNPTVTGILQNLEKKEYIKRLPNPEDKRSKVIILSQKLKDQKLNFERISQEINNTFTKNLDSEQSQLLADLLHELLDGRQK--- ->tr|A0A1F8NBQ8|A0A1F8NBQ8_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_13_60_13 GN=A2Y61_05555 PE=4 SV=1 --------------------------------------ADLSGVEASLLAFVKESKGPVtPSVLARQLHREPHTVSGLVSRMEKRGLVKKEKNLGRRNLVRVTLTKKGEEAFKKQGKVSVPST-IMLTAVTDKERAALTDYLGKL----HR--- ->tr|A0A1E5TYB7|A0A1E5TYB7_STAXY Transcriptional regulator OS=Staphylococcus xylosus GN=AST15_09025 PE=4 SV=1 --------------------ITSKEVANRFNKY--LKQYDISFPNYIVLLYIENEVPVYIKTLCDELYLDSGTISPIIKRLEKKDLIRRLRTEDDERRVKVMLTTKGIK---LKEEFSKISEDVIQqFDMEKEDSLAYYQILKTFAERNIY--- ->tr|A0A0R1LUH5|A0A0R1LUH5_9LACO Uncharacterized protein OS=Lactobacillus acidifarinae DSM 19394 GN=FD25_GL002366 PE=4 SV=1 --------------------------------------GEITAHQIMALSYINQHPGAIQQDLVTLTQRRAPTVSVMLKRFERDNLIVRkIPSD-NNRNKEITLTEHGQEIVRSFQQATTATDELAIADFTPTQTAQLIALLTQMNQH------ ->tr|A5N087|A5N087_CLOK5 Predicted regulatory protein OS=Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680) GN=CKL_2521 PE=4 SV=1 --------------------------------------SELTLAQAHILSYLKRNGIVAFNELVIQLGIDKASLSRILNNLAVKDFIKIEKSHTDKRMKYISMLPLGMKAIINGDYESNKFINQILHFGYEDGNNGIAKAFKE---------- ->tr|Q30VN1|Q30VN1_DESAG GCN5-related N-acetyltransferase OS=Desulfovibrio alaskensis (strain G20) GN=Dde_3472 PE=4 SV=1 ------------------LARELRLVGSYAD------QKGLTVAEAYVLIELGEHGTLSVQQVAQLLLIDAADASRAVQSLILQKLAVLVPEGPPDRAKGVALTEAGHRRLAEVHGEMDSLVRAGLDQLTPGEQKAVADGLMTYARGLRY--- ->tr|A0A0W0YLB8|A0A0W0YLB8_9GAMM Putative transcriptional regulator, MarR family OS=Legionella shakespearei DSM 23087 GN=Lsha_2756 PE=4 SV=1 ------------------IVQELGFLDNQFS------NIG-SFSECHALYELKQSKRLTATQIGKLLKLEKSTVSRLIKSLQDKGYCLVEPDPRDIRSKLVKLSENGEKAAQHIDRVANQQVAVALELLSSEEKKQVMNGLYLYAKALKQ--- ->tr|A0A1I5T9C8|A0A1I5T9C8_9GAMM Putative acetyltransferase OS=Enterovibrio norvegicus DSM 15893 GN=SAMN03084138_03139 PE=4 SV=1 ------------------LLRHRGLLDNIYG------TSGLTTIQCHVLIELEQKN-LNADQLASRLNIDVANANRTLAILINNNNIAYHVK-SAHTQPSYQLTDTGRTRLNAHHEGINQEIALYLEQLDSDEIDVLSSSLSRYNRAMEQ--- ->tr|A0A241W3I7|A0A241W3I7_9GAMM MarR family transcriptional regulator OS=Acinetobacter sp. ANC 4558 GN=B9T31_01245 PE=4 SV=1 ------------------LVRELGMLSRKTI------GTELSPLQSHILIELNQTEQgLGVTELANILCVEKSSISRTLKTLEKSELLSRKINPTDARSVTFSLTEKGESRLIEINQYANQFTAEALMLSSEVELQQLRSTVKNFTKALKN--- ->tr|F6DR47|F6DR47_DESRL Regulatory protein MarR OS=Desulfotomaculum ruminis (strain ATCC 23193 / DSM 2154 / NCIB 8452 / DL) GN=Desru_1501 PE=4 SV=1 -------------------------------QFKELLHENITPAQFMLLKLICHKAECKAADIAQILEVSPAAATNMLERLYKNGWIERGRSEKDRRVVWLKLTPSGKELLTDVEARRIDLMLERFKNVTEEEMVFIKKIFLNV--------- ->tr|A0A0M3T477|A0A0M3T477_9MICC Transcriptional regulator OS=Arthrobacter sp. ERGS1:01 GN=AL755_10210 PE=4 SV=1 --------------LMRWVGWAqMKAGE----DWIR--ERELSHPQSFVLGYLVQNPGAIQRDIAKVTRTTAASVSSLLQGLETRGLVERRTEAGNERSKRVYATPAGVELISGFDTAMAGTEESILTPLDTDERTALHALLAKITAELPQ--- ->tr|A0A1M3EJX2|A0A1M3EJX2_9CELL Uncharacterized protein OS=Cellulomonas sp. 73-145 GN=BGO38_16760 PE=4 SV=1 --------------LIGRISSRlRQAMGDA-FDSAD--LGGLTPLQARTVGFIEAseGRGLIQKDIADVTGTRPATVSALLGTLERDGWIERRTDPSDARRKTLHVTPKARDMVKRFEAGVWASGERQLDVLDADERRTLVALLTKLDQHLSS--- ->tr|A0A175RZ09|A0A175RZ09_9MICO Transcriptional regulator OS=Curtobacterium luteum GN=NS184_04965 PE=4 SV=1 ------------------------------------DLPDIPDAQIEVLRRLDVDGWSSPTALGRALGLARSTVSNLVAAMERDGLVERRLARGDGRSTEVGLTELAQRRLAVYDESAERVLVEAMAAASAADRRVLADvgdVLARLRQRLEG--- ->tr|A0A1A5I6V6|A0A1A5I6V6_RHILI Transcriptional regulator OS=Rhizobium loti GN=BAE38_31515 PE=4 SV=1 -----------------------------------LEPVGLRITQFLTLAALSEVECVAVNALAERLDIERTAMGKMVGFLERDGFVAIEASPTDGRSRLIRLTEAGHHLHEKAAPLWQEAQKQFEELNGANSTSEMRQRLSDM--------- ->tr|E8V390|E8V390_TERSS Regulatory protein MarR OS=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) GN=AciPR4_1635 PE=4 SV=1 -----------------------------------ISPAGVNITQLAVLRCIARRVGEPLVRVAEEMEMDRTSLYRAIAPMIRDGWLTSEDA-STSRFRTAEITAKGRKLLTVANKRWERVQRNIIGKFGQREYGKLLAELDRL--------- ->tr|A0A1C0NVT2|A0A1C0NVT2_CITFR Uncharacterized protein OS=Citrobacter freundii GN=AN688_0225785 PE=4 SV=1 -----------------------------------LDAYGINIAQYSLMRLVINNNPVSLTRLGDIAGLDRSTVGRNVTVLARQGWLQVDRDGMDKRQQQVSITPEGEALIRDAFPSWQRCQHIIEERLGADNVMALQNIFHQI--------- ->tr|A0A0Q9P663|A0A0Q9P663_9GAMM Uncharacterized protein OS=Rhodanobacter sp. Soil772 GN=ASG75_10935 PE=4 SV=1 -----------------------------------LAGDDLSVVQWLLMSELARGEGCTLTHFVRATSRDAGSLSRAIHQLSQRGLLDNRRSHFDRRSSTISFTAAGRAMHERLAPDIEQLTQTINLGADAADLDRI---------------- ->tr|A0A0F7HP14|A0A0F7HP14_9STAP Uncharacterized protein OS=Salinicoccus halodurans GN=AAT16_11975 PE=4 SV=1 --------------------------------------------QLIVLNELQTFGRMTQNELAEKMVISKGAVSQIIKNLENKELVTREVEETDRRNRFLVIEEKGLETISRAEKHAEALREEYMDLIPEEELTNYLNTQRKFTDYLKS--- ->tr|A0A1E5TWT9|A0A1E5TWT9_STAXY MarR family transcriptional regulator OS=Staphylococcus xylosus GN=AST15_12190 PE=4 SV=1 --------------------------------------------QILALSKLKEEGPQKTSSLALSLGYTSGAITKLTNNLIKEDYIVREQQENDRRVILITITDRGLDVLEEAQKQGRNMRNEVYSVLNTQEVEQLLSIQKKLFERVKY--- ->tr|A0A231VR61|A0A231VR61_9MICC MarR family transcriptional regulator OS=Rothia sp. Olga GN=B9K03_10160 PE=4 SV=1 ----------------------------------------LSYVEYMVLAMLSESPELslTMTELALTTNTLPARLSRVVARLEKDSLVERSISREDRRVSICHLLPAGLERIQQVAPGhVAEVRRQIFDHLNEQQVYDLANIGTSVLGDTPSKLI ->tr|A0A1Q8INF1|A0A1Q8INF1_9BURK MarR family transcriptional regulator OS=Burkholderia sp. SRS-W-2-2016 GN=BTH42_28885 PE=4 SV=1 --------------LTYVIGSLDRILRRRMSEALAPLG--LTLAQFTALSVLDANGRASNAQVAERSFITPQSANEVMNAMSARNWVSREPDPTHGRIVLLQLTDEGRAVLRECEQAVKAIEKQMLDDIGVDTAAGVQQHLEAFVRNLR---- ->tr|A0A1Q6TSJ1|A0A1Q6TSJ1_9GAMM Uncharacterized protein OS=Acinetobacter sp. CAG:196_36_41 GN=BHW62_05185 PE=4 SV=1 ----KQDIL-LEQKIGLRLSRIGLLSKIFAGQQFVKNCFDITPEQFTVLYTLKINNGMYLRQLASVTLKDRPNITRIVSILEAKEYLTSAIDKEKRMVKKLYITEKGLDVCEKVLPSILNIWQDTVANISEEEIEKFLETLNKIEVNL----- ->tr|C6J183|C6J183_9BACL Transcriptional regulator, MarR family OS=Paenibacillus sp. oral taxon 786 str. D14 GN=POTG_02160 PE=4 SV=1 ----------------------------------------------------------------------SGAITQIVERMENKGLVRRFQLMRGSNKVNVILTDKGESVYFAYEEFFVKPFdQWIRDELNENELKSFEKGVKKLIEFLNE--- ->tr|A0A1W9TAL8|A0A1W9TAL8_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_123 GN=B6I22_06340 PE=4 SV=1 ----------------------------------------------------------------------KGGVSQNLKRLETKGLSFKEIDPENLSRSIVKLTTKGLTAYWAHKHWHESMDgGFlkYLEALKPGEIETIIQFMERVEDFLKR--- ->tr|A0A0C2E838|A0A0C2E838_9STAP Uncharacterized protein OS=Salinicoccus roseus GN=SN16_02000 PE=4 SV=1 ----------------------------------------LSREQLYIIEMVAEEPGITQKTLIGRLKREQTSISRAVQKLVDQNYLIKRQHHDDMRASYLEVTEQSRETLEELEEKICEVTDDVLEKLDRDEKKALTDILEKI--------- ->tr|A0A101VE46|A0A101VE46_9SPHN Uncharacterized protein OS=Sphingomonadales bacterium BRH_c3 GN=APF78_00605 PE=4 SV=1 -------------------------------DYALLAEGEITTAQAAALMIIGQRAPVSQREVARILEQNESAMTAMVRRLMALGYVERQRAADDVRRWDLLITTAGANALKQAGQAFGQVNRAIEARLSPHEIA----ELARLLNLLS---- ->tr|W4BAV9|W4BAV9_9BACL MarR family transcriptional regulator OS=Paenibacillus sp. FSL R5-808 GN=C169_07188 PE=4 SV=1 -----------------------------------LSKESITGSQAEVLRVLEERGPLSLKELGFLLICEGGSPSRLVNTLVQEGYIIRDTHPKDSRAVILRLSDKGVEKSKRVTLVEQELYTMISRKIDKDKLESINQILCEL--------- ->tr|A0A1Y5SE52|A0A1Y5SE52_9RHOB Transcriptional regulator SlyA OS=Pseudooctadecabacter jejudonensis GN=PSJ8397_01899 PE=4 SV=1 ----------------------------------------LSITEWRVLWDLVEAGPLTVTEMATIQRTDHALISRTIPPMIEKGYVVTTTGAEDRRTSLVAITPSGHTVFDETSATMAQRRTAIKDAFTEAELDTFLALIDRFE-------- ->tr|R7AGR8|R7AGR8_9CLOT Uncharacterized protein OS=Clostridium sp. CAG:43 GN=BN653_01749 PE=4 SV=1 ----------------------------------PSHDMKVNSLPFFALIALDSW-ADQDYTMSELADKlsiTKQQLSHMIKVLEERGLVERIHDTANRRRVYIRICDSGREMMNQMKQEMLSSTLFGLRAYTPEELASMDECLCRLM-------- ->tr|W6S022|W6S022_9CLOT Uncharacterized protein OS=Clostridium bornimense GN=CM240_3139 PE=4 SV=1 ----------------------------------EVGKVKVNSHSFNILLSLNRQ-KDKMLSMSKISNYlqtTKQQLSKLLNDLEDNGYIERIRYKTDRRNVYVKLTEYGMKYLFNLKEAFAEKLDCEISKYSNDDIDILSDVIIKLN-------- ->tr|R5WH04|R5WH04_9DELT Uncharacterized protein OS=Corallococcus sp. CAG:1435 GN=BN495_00318 PE=4 SV=1 ----------------------------------NLVSIKDIPISMTQLTCLNIINRQSQLTMSDLADElnmSNQQLTKVVDALEGFEMVERTYDPKNRRKIYAKVTQKGKDTLQKLKQELDRKLGKIMLEVSDDELDKLYECIAHIA-------- ->tr|W1UG16|W1UG16_9FIRM Uncharacterized protein OS=Intestinibacter bartlettii DORA_8_9 GN=Q606_CBAC00380G0006 PE=4 SV=1 ----------------------------------KISNFGVTYTQLFVLIYIGKNNGCSPKEIVEYLKIDAGQLNRILTKLLEKDLINQRKNNNDRRFNVLSLTESGKNIVQESQKLFYSWDTQVLSDIDENSIQELMNLMKKIIFKLNE--- ->tr|T3DAM3|T3DAM3_CLODI MarR family protein OS=Clostridioides difficile CD160 GN=QEW_3451 PE=4 SV=1 ----------------------------------CLKPYKLTNGLYFYLIYINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGEEVLGDIKNIFSKWDNSIKKEFSDEEYKELVKKLHIVKDIKTT--- ->tr|A0A1Y3RVA0|A0A1Y3RVA0_9FIRM Uncharacterized protein OS=Gemmiger sp. An87 GN=B5G38_08450 PE=4 SV=1 ----------------------------------RLKELGLSQGLLYFLLYVGRHPGCSAGELASVIGADSGHTTRSVEKLVQQGFMTRTRSQQDKRAVVLELTEQGREAFVQAGRWFYQWEAQRTQGMSPEEVTQLKGLLQKAMTGIPM--- ->tr|G9Z7X1|G9Z7X1_9ENTR Multiple antibiotic resistance protein MarR OS=Yokenella regensburgei ATCC 43003 GN=HMPREF0880_03533 PE=4 SV=1 -VKTTSDLFNEVIPLGRLIYMVNQKKDRLLNDYL--SPLDITATQFKVLCSIRCATCITPVELKKVLSVDLGALTRMLDRLLCKGWIERLPNPNDKRGVLVQLTPEGAAICEQCHQRVGQdLHQELTKNLMADEVAKLELLLKKI--------- ->tr|I2B8D4|I2B8D4_SHIBC DNA-binding transcriptional repressor OS=Shimwellia blattae (strain ATCC 29907 / DSM 4481 / JCM 1650 / NBRC 105725 / CDC 9005-7 -MKHTRDLFNEMIPLGRLIVLVNQKKDRLLSEHL--SSLDITASQFRVLCAVQCEESVSPRELSKILSVDLGALTRMLTRLACKGWLERLPNPADKRGVLLRLTPQGNAMCETCRNLVGPdLHQELTKNLTAQEVATLEYLMKKV--------- ->tr|A0A1R4I958|A0A1R4I958_9VIBR Transcriptional regulator, MarR family OS=Vibrio sp. JB196 GN=FM109_00570 PE=4 SV=1 -LGTDKeKQRLSYEEIILRIHRLSDHLAADVQHYL--EPYNLQQADFSILISLYRQGTpyiSSPTQLYQTMLFSSGGLTKVLKRVEDFALIHRIDNLKDKRSKLVQLTPLGLQHIENILDKIKQSRHQRFSCLEIQEQKEMELLLTKL--------- ->tr|Q2IZE3|Q2IZE3_RHOP2 Transcriptional regulator, MarR family OS=Rhodopseudomonas palustris (strain HaA2) GN=RPB_1709 PE=4 SV=1 ----------------------------------LLRAHGLSEQQWRILRALTEVEAIEVTELADRAFLLGPSLSRMLRDLEARKWIARKPAKDDQRRSRVSITPKGLKLIETVAPFSEQIYADIARHFGDAKLAALQDMLGALEADLT---- ->tr|A4X7E9|A4X7E9_SALTO Regulatory protein, MarR OS=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) GN=Strop_2351 PE=4 SV=1 --------------------RVMVVVQTGTARDL--AVLGLSEPDYEVLSTLSERPGHtsTLGEQADKMGWSRSRLSRHATRMAARGLLKRTPDPNDGRGCFLVLTAQGLDALKDAAPAhVESVRRHFIDRLAPEDLVAIEQIAQKLKEPQAGDDR ->tr|U7KG88|U7KG88_9CORY Uncharacterized protein OS=Corynebacterium sp. KPL1986 GN=HMPREF1287_01657 PE=4 SV=1 --------------------AMQRALHKELANALQ-AAANVSEADYAVLAVLQRRRGQstRPHELAAELGWEKSRLHRQLVRMEGRKLVTRRHAEElGPRAIEVTVTKIGEGAFAAALGShTAKVEEKVVSVLTEEELRQLGSISRKITRHLAGGA- ->tr|A0A1F1YB51|A0A1F1YB51_9CORY Transcriptional regulator OS=Corynebacterium sp. HMSC14B06 GN=HMPREF3130_03825 PE=4 SV=1 --------------------NAKRAVDRSIDLQLQ-DSLDISTADFSVLVVLSEAEDNvvRMRTLCESLEWDRSRMSHQITRMERRGLVTKERCACDNRGIDVTLTEHGRTVIEKAAPNhVKLVRHVLFDVLGENiDYQGISAVLDKIAATANAAVT ->tr|A0A0K2H370|A0A0K2H370_9CORY Uncharacterized protein OS=Corynebacterium lactis RW2-5 GN=CLAC_04455 PE=4 SV=1 -------------------------------------RTGLTFADFTLLIALHETEDGImhVDQVCDRLKWNHPRALLHTNRLVKRGLVHTEEPGEDPDsDYVIVLTGVGRHVFVEATPDyVDTVRTEVIGQLSEEDRVNMMKCFHAVL-------- ->tr|A0A1Q2HYQ8|A0A1Q2HYQ8_9CORY HTH-type transcriptional regulator MhqR OS=Corynebacterium glaucum GN=mhqR1 PE=4 SV=1 -------------------------------------SHGLGLTDFRALTLLSEAPDHElrITELSTQVGLNQSSTTRLVARLETKGLVVRDTCPDDGRGIYAVITEAGLNLVHTLAVPyVERLQTLVASTITNDPATS--RAFSTILN------- ->tr|A0A1V9BMA0|A0A1V9BMA0_9BACI Transcriptional regulator OS=Geobacillus thermocatenulatus GN=B1692_16355 PE=4 SV=1 ---------------------------------------DLTQKQ-VMLLELLRHQTMTINEIAESFSMTPSAASQLVRKMEEKAYVRRDINPADRREIIVRLGQAGQAYHKKMDEVELHLMEKYYGKLRREDLEKLKEINDKLYDLI----- ->tr|A0A0A3YIF9|A0A0A3YIF9_9ENTR Uncharacterized protein OS=Erwinia typographi GN=NG99_25650 PE=4 SV=1 -------------------------------------DENISTSLFTLMEVVSLSPGIDIRTAAQMASIEESNAVRIVMRMVRTRIMSDPRDPNDARRSLLSLTGNGQAIFEQLQARLPLVQRGLTQKLPPVAVEEFHRLTRLV--------- ->tr|A0A222TJK0|A0A222TJK0_GORRU Transcriptional regulator HosA OS=Gordonia rubripertincta GN=hosA PE=4 SV=1 --------------------------------------PDVTGPQYAVLWAIAERKVATHTEIATLASLDSSTTLDIVRRLTARGWIVPVADVVDKRSRPVRLAEPAITALRFIEPAVSGVQAKLIEPLTETAQTQFIDNLRLV--------- ->tr|A0A1I2T958|A0A1I2T958_BACME DNA-binding transcriptional regulator, MarR family OS=Bacillus megaterium GN=SAMN04487776_102881 PE=4 SV=1 ----------------------------------LLQHYGITPFQYHILLIVERARTMPVTKVADEIKASPSVITASITRLHELNLVERYHSKRDRRKVMVELTNKGKQVIQAAEKDMQQEVEKLFACYKEEEQQQFLTLCRQLDEHV----- ->tr|A0A1M6B6E2|A0A1M6B6E2_9CLOT Transcriptional regulator, MarR family OS=Lutispora thermophila DSM 19022 GN=SAMN02745176_00293 PE=4 SV=1 ----------------------------------------LNKSQQKALFIIQKKGRVMPSSLGKAMDMQKGSLTTLIDSLVEYGFVRREADCEDRRKQWIILTSQGEEYISKLMSCFEKEFERIFEKVDSQDIYKLLESIEFA--------- ->tr|R7LZM5|R7LZM5_9FIRM Uncharacterized protein OS=Acidaminococcus sp. CAG:542 GN=BN701_01713 PE=4 SV=1 -------------------------------------GVPLTMIESHTLTYIDDHPGTTVTELTHFWHKTKGAISQIVTRLEQNGLVSKQKKADNAKLVRLYTTEAGARASNAHKMYdiidITKTLGEIGEKCTPEEIDTFFRVMQVYYGVISK--- ->tr|A0A1P8XC27|A0A1P8XC27_9MYCO MarR family transcriptional regulator OS=Mycobacterium sp. MS1601 GN=BVC93_17210 PE=4 SV=1 -----------------------------------LKPLGIGMPEYVCMSQLAGRPAESNAELARRTGVSPQAMNNVVKSLQELGALTRPDSVSTGRSLPVRLTPKGRRLLVRAEAVVRKASEQILTPLSAEERVTLERLLRSLDLNAV---- ->tr|R5D6P1|R5D6P1_9FIRM Uncharacterized protein OS=Dorea sp. CAG:105 GN=BN457_00869 PE=4 SV=1 --------------------------------------------------------GLTAAGLCELCKEDKAGISRILNDLENRNFIAYEATgAAHRYRSRAHLTDVGIACAREMRSFISHALEEASKDIAEPQRKIFYKTLFTIADNLEHLSK ->tr|E7MKM3|E7MKM3_9FIRM Uncharacterized protein OS=Solobacterium moorei F0204 GN=HMPREF9430_00068 PE=4 SV=1 --------------------------------------------------------GLTNTELVECSKMDKAAVSRSLADLAKGKFIRFEYRnGKSRYGAHAVLTTTGKEVTEHIVERIGKVLTKALGHLSSEEKKFFVANMATVASAMLEIVE ->tr|A0A1E5U6G7|A0A1E5U6G7_9STAP MarR family transcriptional regulator OS=Staphylococcus succinus GN=AST12_08470 PE=4 SV=1 --------------------KSYCLMKDKYDSLLQKYDLTEAKFSIMMLLTYEKDMTLAPSDLAEKLGSKKSTITGIIKGMEKRNLIRRKVLPNDKRTNYVQLTNEGSELLKRFLPFNYDLVSKVFEVFSEEEKEQFYMLSNKLKNHLEK--- ->tr|A0A0J8WYV9|A0A0J8WYV9_9MYCO Uncharacterized protein OS=Mycobacterium conceptionense GN=ACT17_12050 PE=4 SV=1 -------------------------------------TGELTLTQCSVLYHLTEIRRARVIDLAAREHVTTATMAKAVRRLQELGMVRRQRDLSDYRSSWIEITTKGVQTQQAAVAG---LREAMVNELSAEEISALQTAL------------ ->tr|A0A0P1IQQ2|A0A0P1IQQ2_9RHOB Transcriptional repressor MprA OS=Thalassobius sp. CECT 5114 GN=TA5114_01741 PE=4 SV=1 ----------------------------------------ITVAEWRILVNLAYSNSKTVRDIQQRVHLDKAKVSRAVVGLEDRGYLTKKIDPDDRRLLHLELTEEGETLVAELVPLAQEFQSKVAEKFQDdfaTLQSQMTQLMKALSDG------ ->tr|A0A0M6ZM82|A0A0M6ZM82_9RHOB CRISPR locus-related DNA-binding protein OS=Labrenzia alba GN=LA5096_00173 PE=4 SV=1 ------------------ARRTANLLTRHYNRHMAALGLELT--QAQLLAVIADGTAPSASAIARYLGIDRSTLARNLRPLEAAGLIRRR-E-TKGRTVLPILTPAGEQKVVEIHQRWLAAQAELSAMLGPEGADAVRSHMSALRK------- ->tr|I5BAC1|I5BAC1_9SPHN Regulatory protein MarR OS=Sphingobium indicum B90A GN=SIDU_15594 PE=4 SV=1 ------------------LRAANRAVMKHYVDSMAGSPVNPV--QMSLLMRVYYLRNATMQTLAQHMETDRTTTTRNVDVLVRDGFLEIGEG-KDRRQRLVRLTERGHEALEVSIPKWRKAQDELKNALGDELWNNILREARTLIE------- ->tr|G0AAQ4|G0AAQ4_COLFT Transcriptional regulator, MarR family OS=Collimonas fungivorans (strain Ter331) GN=CFU_3524 PE=4 SV=1 ------------------LRQLTRKMTNIYDHYLAADELTIS--QYSLLARIGKYGPIGVIPLAHNMGMDRSTMSRTLKPLIGAGWIETVDlpleMLTDKRSFGVRLSAEGERKWKQSKPNWRKAQDVINTILGDQTHHALMSLVDDANV------- ->tr|A0A160TER8|A0A160TER8_9ZZZZ Transcriptional regulator, MarR family OS=hydrothermal vent metagenome GN=MGWOODY_Tha2183 PE=4 SV=1 ------------------LRKADRVINHVYNRHLAECGLSVS--QFSVMRAMHYAGTCTSQVIQDILVLDQTTLSRNLKKLVSDGMVVMKEDKGDRRRKLLSLSAKGKIMFSAGEKQWKLAQNEMRETLGNSIADQIIELSDAIVG------- ->tr|S5P7U0|S5P7U0_9PROT Transcriptional regulator OS=Arcobacter butzleri 7h1h GN=A7H1H_0190 PE=4 SV=1 ------------------MRQISRKITNIYDEFLKPSNLNVT--QYSLLSNLKRVQPIKMNDFSKVVKLDRTTLVRNLKPLINLSLIEIKSI-DKSKAQLLELSQKGIELQNEGYKYWQKAQEYIEQTINHEELEIFYTIVKKMES------- ->tr|A0A1B3ZIC0|A0A1B3ZIC0_9SPHN Uncharacterized protein OS=Sphingomonas panacis GN=AWL63_23670 PE=4 SV=1 ------------------LRKASRAFARLGDQTLAPCGMTAV--QFTILRSIENRGPdgWPLSKLAETMLMERTTLYRALSPMKRAGWIEISNP-NAGRVKVVAATAGGRLAFERANALWAQAQARILTAFGTDRWRVLSGDLTDLTG------- ->tr|A0A1Y1STQ9|A0A1Y1STQ9_9RHOB Transcriptional regulator OS=Stappia sp. 22II-S9-Z10 GN=ATO13_11326 PE=4 SV=1 ------------------LRRIARQITTIYDGALAENGVSIV--TYAVLSALSREEPLTLSALADRVGTDRTTLSRTVERMRQAELVAATPG-DDRRERRLSLTDHGRDTVAAARKSWRETETMLIERYGADRLATLHELLADLEA------- ->tr|A0A1N7BAC5|A0A1N7BAC5_9MICO MarR family transcriptional regulator, transcriptional regulator for hemolysin OS=Microbacterium sp. RURRCA19A GN=SAMN05880568_ ---------------------------------------DAPAAQWRTLKLLREHGPQRVGDLATLSRVSQPGMTRLVHQMESAGLVARGIHADDSRVSVVSATEEGLRELDRWLAALSAALAPHVADLTDAEWDAVRTsa--DALALRVGMQ-- ->tr|F6F269|F6F269_SPHCR Regulatory protein MarR OS=Sphingobium chlorophenolicum L-1 GN=Sphch_2937 PE=4 SV=1 -----------DEQLLTDLSRVITLMRRSFDRAMTEQGASLA--QTKLLTCIKAQSGtARAADIAEIMSIAPRTVTEALDGLEREGLIQRTPDKADRRVKRLTLTPAGEAAVAVTEPLRRELSAKMLAALNPSDRAHFHAALQKLLEAL----- ->tr|A0A1W9JGQ6|A0A1W9JGQ6_9PROT Uncharacterized protein OS=Proteobacteria bacterium ST_bin13 GN=BVN33_16600 PE=4 SV=1 -----------VDALLSGVIGLLRRFKLEPGLLADSvyADLHHN--DIGLLTHLQPGDGRPVRVLASEFGAPDSTISSALDRLARRGLIRRIPSETDRRSVLVSLSAEGEVLADRLLQIQRDNCRAMLAALPPGDRATLIRLAGVMVTDA----- ->tr|A0A1X9UMK1|A0A1X9UMK1_9SPHN MarR family transcriptional regulator OS=Sphingomonas sp. DC-6 GN=HY78_02760 PE=4 SV=1 -----------EEELITGLAKAYMLMHRRVNRAMTKQGASLA--RTKMLAYIRKAGGsARAADIADLFDLAPRTVTESLDSLERDQLIVRTSDPQDRRVKRLAITPLGESAIAATEPLRKELMAEICAVLSEDDRVQLHDILSRFVASL----- ->tr|W0EEP1|W0EEP1_9FIRM Transcriptional regulator OS=Desulfitobacterium metallireducens DSM 15288 GN=DESME_13870 PE=4 SV=1 -----------------------------------FSKTGISDSQFSVLLALEELGPLTMGELCKQIFTACSTATDLANRLERDELVERIKDDKDHRVVRMHLLPKGKKIVQDYIQERQHFLEAVLEESPSNEYIALLETLEGFAERMDISEN ->tr|A0A1F7BJ98|A0A1F7BJ98_9BACT Uncharacterized protein OS=Candidatus Peribacteria bacterium RIFCSPHIGHO2_01_FULL_55_13 GN=A2881_04300 PE=4 SV=1 -----------------------------------MRGMGVSMLQLHGLLTIREKPGMTMKELASHLAVTSPTATVFIGRLESQGLVERIHDTKNRKMVRVSLTAHGRELAEGAYRHFEDAFREVFGMLPKAELHTLIHIFTHLIRLHTEKTH ->tr|A0A0F4M017|A0A0F4M017_9LACO Putative transcriptional regulator, MarR family protein OS=Lactobacillus mellifer GN=JG30_00730 PE=4 SV=1 ------------------------------------KQFGLTGVQVQIIDYLNHLpqNqFVYQKDIERAFNIRRSTATSVLQKMEENELIVRNVSPSDSRVKVISALPKAEELQPQISQFLESSNAQLLSCLSTLQRHSFLKALEKMPQELAR--- ->tr|W1UZV1|W1UZV1_9LACT Uncharacterized protein OS=Leuconostoc sp. DORA_2 GN=Q611_LSC00312G0004 PE=4 SV=1 ------------------------------------QPHGLTAVQMTIIDYLSNASrVTTQHDIEQEFNIQGSTVTVMLDRMANKNLITRQKSTKDKRINEIHLTTRGFEVSDIIKGYIAEHDSRMLAPFTDAEQTVILQFLKMVGQSVTQ--- ->tr|A0A0M2U4K1|A0A0M2U4K1_9FIRM Uncharacterized protein OS=Clostridiales bacterium PH28_bin88 GN=SY88_10370 PE=4 SV=1 -----------------------------------LDKYGLPPASRAVMRQVHHNQGITVSEVSRRTGMVKSHVSKTVDSLVEQGFLEKRPDPSDQRLIRLYITEKAGEHFGQIQVEIRHRLSEVIAEFPEEKIEAITDGLRTLKAILEQG-- ->tr|A0A1T2A5G9|A0A1T2A5G9_9RHOB Uncharacterized protein OS=Thioclava sp. F28-4 GN=BMI87_05730 PE=4 SV=1 -----------------------------------LEPGPCTPIEISVMRFVGRNPGVSARAAADACRLPTSNFARVLKGLVAKGLLERRSDPQDARIAHLHPTELAEKNSLR----MREHWAAALSGVglERDKIAATTQALRRIEAHLSAA-- ->tr|R5LP39|R5LP39_9FIRM Bacterial regulatory protein MarR family OS=Eubacterium sp. CAG:115 GN=BN470_00516 PE=4 SV=1 ---------------------------------------------WILYFLRLNNGTCQQKELASSLSQPKQTTNSAVKQLERGGYVTLKCGS-DRRCRLVELTPKGSGLAVSTSDHVIAAERETWGDFTEEEQDSLIELLSKYNKRLKT--- ->tr|R5DZ77|R5DZ77_9FIRM Uncharacterized protein OS=Eubacterium sp. CAG:86 GN=BN798_00415 PE=4 SV=1 ---------------------------------------------WILYTICYYGEGVTQKTICEEWFYSAQTVNSSLKLLEKKNLIELRLAPGNKKNKQIFLTEEGKDMTNRLIVPVIEAEKLSFDAFDIQELKKMFRLSFEHVKQLEK--- ->tr|R6L8N9|R6L8N9_9FIRM Uncharacterized protein OS=Coprococcus sp. CAG:131 GN=BN485_00212 PE=4 SV=1 ---------------------------------------------WIIYILTIENkAELTQAELCDTWFIPRQTCNSAVKKLEGKGLISLTTHKGAGNIKYLSITENGVSFANKYITPLTNADISSFSSFTDEERELLLSLMQRQLDYLKK--- ->tr|A0A0E9F6J7|A0A0E9F6J7_CHLTH Transcriptional regulator Hpr OS=Chlamydia trachomatis GN=ERS095036_10918 PE=4 SV=1 ---------------------------------------------LVLSAIYDSKEECTQKKISQRWLVPKQTVNMILKDFEKQGLVELSPMRTDKRRKTICFTPKGKEYAKTILSKLRKVEMNAIDEMGIERMKRFNEDAALFVKLLGK--- ->tr|A0A1J8KNC2|A0A1J8KNC2_9FIRM Uncharacterized protein OS=Eisenbergiella tayi GN=BLA28_30880 PE=4 SV=1 ---------------------------------------------LVLLSLREGKEPCTQKQICEQWTLPKQTVHSILRNFLEREWVTFHVLENDKWNKGVSFTRSGSAFAGEVIDKLQSLECRVWERLGNEKSNALLESTILYVSYFRE--- ->tr|A0A1Y4IVB9|A0A1Y4IVB9_9FIRM Uncharacterized protein OS=Lachnoclostridium sp. An196 GN=B5F29_03465 PE=4 SV=1 ---------------------------------------------WSLLLIHDG--VETQSRISEQLFMSRQTLNSAFKQLVKKGLIVLEPYEDNQRTKRAVLTPSGDRLVEEQVTRMHRIEEQAWEKFSQEESEALARLTRKYTDVLGE--- ->tr|R7D4H5|R7D4H5_9ACTN Transcriptional regulator MarR family OS=Collinsella sp. CAG:289 GN=BN589_00478 PE=4 SV=1 ---------------------------------------NAVSGEMAVMRALMLANgELSPSQIADRAWVSAPRVANILRNLEAKDWVTREPDKADRRRVIVKITEHGLACIEEKRELSNRKTGEFLAELGPDDAHELVRLIHRMNEIIEKNQ- ->tr|R6W404|R6W404_9FIRM Uncharacterized protein OS=Ruminococcus sp. CAG:382 GN=BN636_00121 PE=4 SV=1 ---------------------------------------GFHKGGQFVLDYLANQKnGIsPQKNISRDMIVSSARITVLLKNLEEKGYIRRMKDPSDSRQELVSITESGRDAIGRLRDVLITRTAEVLEALGSHDAEEYFRIQKRIFELTYNTR- ->tr|A0A0R2AYE6|A0A0R2AYE6_9LACO Uncharacterized protein OS=Lactobacillus brantae DSM 23927 GN=FC34_GL001071 PE=4 SV=1 ---------------------------------------ENALGVDYVLFQYLDQHeNVTPSDLSQALHVTTARMTVILRRLEKANMITRSAHPTDLRKFIIALTPTGRKKLKDQETKQLTYLTDLMAYLGEEDAEAYIRIVSKLAKRRNQSK- ->tr|R6GWG8|R6GWG8_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:137 GN=BN490_01067 PE=4 SV=1 ---------------------------------------MRAQGESLVLHLLARHPdGMVAEEIRQIMDVSSARVAAILANLERKDLIIRLIEPEDRRRLRIMLTPAGQTHAETEDAYIIDRLEQSLAVLDDEEIQCCIRVLHKLENLHHR--- ->tr|A0A1C5M544|A0A1C5M544_9CLOT Transcriptional repressor MprA OS=uncultured Clostridium sp. GN=SAMEA2393091_00524 PE=4 SV=1 ---------------------------------------SSMKGEAFLLMYLWKKQdTATPGELGKAMKTSSARVAAALNNLERKGMIARKAEEKDRRKIRVELTGKGEEQAKQWQKMPLCMVTRLMEQLGEEDAKQMLHILKRINEIMPQID- ->tr|A0A1C5Y4T5|A0A1C5Y4T5_9FIRM Homoprotocatechuate degradation operon regulator, HpaR OS=uncultured Ruminococcus sp. GN=SAMEA3545434_01456 PE=4 SV=1 ---------------------------------------ELFQGESKVIVYLSTAEgIVYPSDISRDLMISRQRVTSVLSAMEKKGFVSLVRDPEDKRRVQVKLLPKGEKSIEEKQQRLEKYFSVFVDALGEENLKNLLDSSEKAVEALEHTM- ->tr|A0A0M7ARZ9|A0A0M7ARZ9_9RHOB MarR family protein OS=Labrenzia alba GN=LA5096_05189 PE=4 SV=1 ----------------------------------------LNPSQFAALSYLARANrfSRAPSHVAEYLVTTRGTASQTLKALARKGLICESRSETDKRSIRYDVTDLGKDMMKAP-SGLANVIDDLPDEivnGLTGSLKTLVREILKTRK------- ->tr|A0A1F4G2Z7|A0A1F4G2Z7_9BURK Uncharacterized protein OS=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_63_240 GN=A2711_17215 PE=4 SV=1 ----------------------------------------MDIVHLRALLFLDRANrySNTLAGLTDYLGLTKGTVSKSVALLEQAGHLRRTPDSQDRRVQHLSLTASGEDVVQRLLThlRLGDIARCMGMPqaeQATQMLRHVLSTCQRLNQ------- ->tr|A0A127PXP7|A0A127PXP7_9BURK MarR family protein OS=Collimonas pratensis GN=CPter91_0127 PE=4 SV=1 -----------------------------------YQPFDLTAPQGFVLRTVLRRPGLLSSEVASVFGIARPTATRLLDALLAKQLIERRPSAEDGREWNIFPTAAGQALDKPINAVSAEVAQRLRAQVGSDRFDDSIAALRGVRESIG---- ->tr|X0PDY1|X0PDY1_9LACO Uncharacterized protein OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=FC83_GL001073 PE=4 SV=1 --------------------------------------------QGKILVLLAQEDNLPQKEIATRLNLTPQSTAEFVGKLARKHYVHKTKSQKDRRITLIQLTGQGRDALKNIDNTIPSYL----EFLDDDEQQQFGKLLAKMNLGL----- ->tr|A0A1F1DDX6|A0A1F1DDX6_9STRE Transcriptional regulator OS=Streptococcus sp. HMSC072C09 GN=HMPREF2893_09630 PE=4 SV=1 -------------------------------------GISLTRYQ--ILQYLLEQAPCNQIAVQERLQIDPAALTRHFKILEKEGFVHRSRNPKNQREIVIHLTDTAYNWLVNRPPRYHVaVKEQMSRILNAQEQEQFSYLLDKLV-------- ->tr|A0A0C2VSU3|A0A0C2VSU3_9BACL Uncharacterized protein OS=Jeotgalibacillus soli Cunha et al. 2012 GN=KP78_03620 PE=4 SV=1 ---------------------------------------DLTPVQYTALEFIILRESVSARALSDFLKVKPAAVSSLITRLEKKNFISRMEGKADRRMINLSATSEGQEVYDRIFHRFSTMLDQIYTKLSCDDHMHFERIIRKLNEETK---- ->tr|R4K176|R4K176_CLOPA Transcriptional regulator OS=Clostridium pasteurianum BC1 GN=Clopa_1958 PE=4 SV=1 ---------------------------------------NLQPQDMYILERIYFKKKLKVKDISKEYNIPASTTTGIIDRLEDKKYIKRTRDNVDRRIVELIATEEGCEVIQNHINQDKIFAENLFNTLEENKKIAFKQLLSELINKVN---- ->tr|A0A134ALI0|A0A134ALI0_9FIRM Transcriptional regulator, MarR family OS=Peptoniphilus coxii GN=HMPREF1863_00047 PE=4 SV=1 -MKAREFLWTYWNLLKEANDTKMSLMDYFSENY------GLTQLQLLVLGKIDSLDDTSIRSIARSLHRDHGNISKICTVLERKGYVYRERSVTDSRIVHVYLTEQGEKYIDEFSSIVAPLYDKLGDHLTDGDLRFLLKSMEIIESLFNQS-- ->tr|M3VEV6|M3VEV6_9ACTN Putative MarR family transcriptional regulator (Fragment) OS=Gordonia paraffinivorans NBRC 108238 GN=GP2_023_00010 PE=4 SV=1 -----------------------------------LKPFRVSKRGLLVMITLFvdPDSSKALGQLSKILMVHPTTVTLTIDQLESAGLVERRPHPTDRRTVLASLTETGQQTMKQIADSLAESDFGF-PAAAPDSAHALTVALHQV--------- ->tr|A0A0N0YQY5|A0A0N0YQY5_9ACTN MarR family transcriptional regulator (Fragment) OS=Streptomyces sp. NRRL F-6602 GN=ADL27_41755 PE=4 SV=1 -------------------------------------------------------------------MPVPKPLSLPFDPIARADEsWRERWGPVPAMAAITSIMRAHQ--------------I---------LLAEVDAVVKP---------- ->tr|A0A1H4KVA2|A0A1H4KVA2_9NOCA DNA-binding transcriptional regulator, MarR family OS=Rhodococcus koreensis GN=SAMN04490239_0928 PE=4 SV=1 -----------------------------------LQPHGLSYPRYELLNLVAgtADGTIDKVVLDHALDRHSTTTRTMLQGLECSGLVEWYRNPQDRRSTIVSITAAGRERIQRATRVLDNAMPSDRalFDCFTDTAHSLSLTLRDF--------- ->tr|A0A1Q7QGJ3|A0A1Q7QGJ3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_40CM_2_65_8 GN=AUI42_01225 PE=4 SV=1 -----------------------------------AAQYGLSAVQAKVLLRLPAGGATTMQGLAGQLQYDASDLTESWIASSPWGAVRRQPHPEDRRVKRVELTDDGRRMRKAFWEKLTNRSG-PLRRLNSRELISLRALLATA--------- ->tr|A0A094IE95|A0A094IE95_9MOLU Transcriptional regulator SlyA OS=Mollicutes bacterium HR2 GN=slyA PE=4 SV=1 ---------------------------------------ELTKNEIKTLMQLKFRGRQSLSYYSEKIGLKKGSFTSLTDKLEEKGLIKKSYIEHDKRKKIIIPTQKGIELTDKFYNSFVNHLSIKISKLSDSDLVLMESAINILSKIDLS--- ->tr|A0A1Q9N8M6|A0A1Q9N8M6_9ARCH Uncharacterized protein OS=Candidatus Heimdallarchaeota archaeon LC_3 GN=HeimC3_02450 PE=4 SV=1 ---------------------------------------DISSKEFQILYLISNYEPCNLTKISEIVQYPNSTVCRIIDKLNEAKLIKKHdsKNNSDRRKKKLSPTEKGEKIINIFIKQHIKISTFIVGDIPNQNLALVLEKLKKFFSHF----- ->tr|A0A239ZB11|A0A239ZB11_CLOCO Transcriptional regulator OS=Clostridium cochlearium GN=SAMEA4530647_00381 PE=4 SV=1 ---------------------------------------KISPYPVIILNQLDISKPTTLTDIRERLGIPNSTISTVVDKLLEKELVRKEKDATDKRRTFLYLTEKACEEEKKIIKQHVEVFKEILCKATEDDLNTLIDATKLFIKLIEE--- ->tr|E4SHP0|E4SHP0_CALK2 Transcriptional regulator, MarR family OS=Caldicellulosiruptor kronotskyensis (strain DSM 18902 / VKM B-2412 / 2002) GN=Calkro_ ----------------------LSLFPMITKNILKkdefSEKYGLPPRFIHILHITDVFGPMNMSELAKRLNISAPNLTPIVDKLIAEGYVQRLKDESDRRISIVQTTEKGKELLSLHTQWVNQNLEKNLSRLSEDEIEELWYLLKRLKTLVLK--- ->tr|A0A101GUM0|A0A101GUM0_9FIRM Transcriptional regulator, MarR family OS=Desulfotomaculum sp. 46_80 GN=XD84_0992 PE=4 SV=1 ----------------------HIVLEYIRENFFRpvdqVTRSRLSHVQFCAMSILCRRGSLSMSELADEMRISKQQLTPLIRKLIDRKMLSRKTDPDDRRIVRLEVTGIGRSTLEDLFNELKMALVEKLKELPVAELDELGQMLKRILDILKS--- ->tr|H3KA03|H3KA03_9FIRM Uncharacterized protein OS=Megamonas funiformis YIT 11815 GN=HMPREF9454_02076 PE=4 SV=1 ----------------------FDIMMTYNHKLWRTAALPLPLNHFAVMYYLFEkEDTfATVTELAKHLSISKQQMSPIIDKLVKKEFIKKTCLSKDRRYSQISLSEKGRNFLKEHQKSQRLIFMESMTDLSDSDTEKFDQSVRLVKKMMAK--- ->tr|G2G278|G2G278_9FIRM MarR family protein OS=Desulfosporosinus sp. OT GN=DOT_6119 PE=4 SV=1 ----------------------SNLVPLFARRLLRpleqEAKNLTSPVHMHTMTVLCEKEYFTMTELSNEMTMSKQQMTPIIDKLVANGYVQRKHDTIDRRSIKICLTSVGIDFLNNINNEVTNILKKKIECLDTDDLASLNDALDNLFRIINK--- ->tr|A0A0L8F1L0|A0A0L8F1L0_9CLOT Uncharacterized protein OS=Clostridium sp. DMHC 10 GN=AGR56_14685 PE=4 SV=1 ----------------------FSVMPVFSKIILNvgdkvLKENGIAVAHIKVIYMVKRYKKINITDLGKALSSPKSNVTSWTNKLVKMGFVQRVFDEKDRRVIYIKLTDKGEAFFQFYEEALRKSFEEKLWKLSDEDLKLFKDTLDNMRKLVDK--- ->tr|A0A1C3CIE4|A0A1C3CIE4_PAEPO Transcriptional regulator OS=Paenibacillus polymyxa GN=A7312_03795 PE=4 SV=1 ----------------------LGLFPIVKKKFFTygplDFPLHLSPNNFQVLMLLREVRSSTVSDLSKQLNVSRPNMTPLLDKLVEHGLADRQSCDSDRRVVNVAITQEGDAFCEQVFHTFSNKIQERLVYLPEEDLLHLSETLNELKHILLK--- ->tr|A0A1V5PAY6|A0A1V5PAY6_9BACT Transcriptional repressor MprA OS=bacterium ADurb.Bin363 GN=mprA_5 PE=4 SV=1 ----------------------SQLCTDMAEKFFQaiyrrpSKADQIPLSHLKVLMFLSKKESFKMKDITEELGIASSSATDLIDKLIKEHLVERYRKPDDRRVVKVKLSEKGRNLIVELKEMKRKFWVTIIENISEEDREDLVRYHRKFYNIIGK--- ->tr|L7VPC8|L7VPC8_CLOSH Transcriptional regulator MarR family OS=Clostridium stercorarium subsp. stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 117 ----------------------------------VLEDSALTFHQVYVMKIIGAKTDVNLTSLCKELNLSKGAMSLTVNRLEEEGYVKKCENPSDRRNRNIVLTPKGEEVLNSTREKLREAFDKLTKDLTIEELENIKNSLMRLNETM----- ->tr|C9YJN2|C9YJN2_PEPDR MarR-family transcriptional regulator OS=Peptoclostridium difficile (strain R20291) GN=CDR20291_0782 PE=4 SV=1 ----------------------------------NFKENGLTHQQIIVIKLVAHNQELTISQLCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQESFDDIFKNCDENELSDLVKNLRNILAKV----- ->tr|G6BA47|G6BA47_CLODI Transcriptional regulator, MarR family OS=Peptoclostridium difficile 002-P50-2011 GN=HMPREF1122_02728 PE=4 SV=1 ----------------------------------------ISLVELSILEIVEQHPNSMMKEISSTLELPKSTLTSAVKRLELKKLIKRNPCIKDKRAYNLDLTELGLKAQQEHREIEATVFKNILHQLDKDEIETFIHIFSKAVNKI----- ->tr|A0A0L8EP44|A0A0L8EP44_9BURK MarR family transcriptional regulator OS=Achromobacter sp. DMS1 GN=AD428_15215 PE=4 SV=1 ----------LERFLTYRLHAVNKISDRDTARAY-LADCGIPLGEARCLAAIGRYAPLSVNELARAANLNKGQASRSAQALVERGLVEKKNSDTDGRGVVLAPTPSGQAQYERIIALISRRNAEIFGCLSAEEQRQFGDMLDRL--------- ->tr|V4YMP8|V4YMP8_9PROT DNA-binding transcriptional repressor MarR OS=Betaproteobacteria bacterium MOLA814 GN=MOLA814_00048 PE=4 SV=1 ----------LDRTFTHRLHTLSKLTDRVTQATY-ESRADIGLSEGRCLAAVGAFRPLSINDLAARANLDKAQASRAAQALVARGWVNKVTGMKDRRGVLLTLTPEGNSRWSKLKRVISDRNAEIVACLDDGEQTLFSTLLDRL--------- ->tr|A0A1L6LHG7|A0A1L6LHG7_9DELT Uncharacterized protein OS=Minicystis rosea GN=A7982_06487 PE=4 SV=1 --------------FIDTFGAVKRCITAAAGQAY--AALEIGSTQAKFLRHIGKHSRISQAELARATETDPGLTGRTLQSLIERGWVLRARSDEDRREYVLELGPEGRRAVARVEKQRLQLGERVVAALDERDLDDFDRIAKKI--------- ->tr|A0A089HKP6|A0A089HKP6_PAEDU Uncharacterized protein OS=Paenibacillus durus GN=PDUR_11910 PE=4 SV=1 --------------------------------------SGLTVHQLDILRLIRTAPRLTQKEVTERLRMPKSRVSLHIDALVDKEFAVRETSPQDRRETLLRSTPAGETLCEHYdrdDLSR-KALAGALRQFSPEEIELLLTMHERLLNEL----- ->tr|A0A1S2QNC2|A0A1S2QNC2_9BACI Uncharacterized protein OS=Bacillus sp. MUM 116 GN=BIV60_26940 PE=4 SV=1 --------------------------------------LGITTVQLKVIHKLASNPDISLGELAEKLRMTSSTASSVIERLVQIGLVERVTPPENRRVVSIHLTEKGKKILDQFyssDSIFIKKTND-VLKLSERDISELIRLQKIILKKLSI--- ->tr|A0A1Q4BE26|A0A1Q4BE26_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 62-17 GN=BGP04_12725 PE=4 SV=1 ------------YAMVQCTSRLLACRDAFGND------LSLTASQFAVLmgvAYRQNSEGVTIKELAEHVALASTHVTTEVGRLERKGLLLKRQNAADRRSVHVSLSTKGEEAIAHVSPLVRMVNDTLFEGIDPEALETARQVARQLILNSDEALA ->tr|A0A1Q4DMT0|A0A1Q4DMT0_9RHIZ Uncharacterized protein OS=Rhizobiales bacterium 64-17 GN=BGP08_17965 PE=4 SV=1 ------------ADLFAAAAGMLALRRALATT------VDLSAAEFAILlatWQQEQKGEVGISSLAREVHVAAANVTAEVGKLVRKRILHKQPHPRDTRAVLINLTDKGHEILARLTPVLQEINDRLFVGNSTRDITVVGNFLHHVADETPYSIN ->tr|A0A158L205|A0A158L205_9BURK MarR family transcriptional regulator OS=Caballeronia terrestris GN=AWB67_07256 PE=4 SV=1 ------------NGLLPFAARLLSVRDGFGTI------IGLTGIQYSLLvsvAHLSHGEAVTVNRLADHLHLSGAFVTIETGKLKKLGLIDKRSDPDDKRKMRLTMTSNGVKLLRELAATQQRINNVLFEGVTKAEFKALCSVVDRLVANGDRATL ->tr|A0A193KZ39|A0A193KZ39_9ACTN MarR family transcriptional regulator OS=Streptomyces sp. SAT1 GN=A8713_035585 PE=4 SV=1 ----------------------------------------LDRSAYVLLTRLETGEPLTLKELAHTFQADVSTINRQMSAMLRHGLVERIEATTKGGARTFRPTPLGLERLAADRAISRAGAARLIeaAGWSPERTQQFLTLMIEFNHGIEQ--- ->tr|A0A1A9DGP8|A0A1A9DGP8_9ACTN Transcriptional regulator OS=Streptomyces sp. MnatMP-M77 GN=YW3DRAFT_07040 PE=4 SV=1 ----------------------------------------LDRSAYVLLTRMETGEPLTLKELAHTFQADVSTIHRQVGTMLRHGLVERIDAATRAGARTFRPTPLGLERLEADRAISRAGAARLIeaAGWSDARTQEFLTLMVEFNHGIER--- ->tr|A0A0X8L4C4|A0A0X8L4C4_9BURK Uncharacterized protein OS=Burkholderia sp. PAMC 26561 GN=AXG89_07175 PE=4 SV=1 -----------------------------------TEQSALSPTEWRVLFAVMHAGTAIAADLSRTLQINTGYLSRLLNDFERSGLIVRSPYAGDARSRHISLAPAGESVLAATSTHVRNNVSTALEAMTPDEGSQLMASMELV--------- ->tr|J4K9M4|J4K9M4_9FIRM CodY helix-turn-helix-like domain protein OS=Peptostreptococcaceae bacterium AS15 GN=HMPREF1142_1167 PE=4 SV=1 -------------------GKLMEIVNDFSDLFSTWDCYdEFTKRDTCILTMILVHTrqgnKITTSNISDLLGITKPAISQALKKLEQGGFVRRKVNNDDRRVVYVYLTKKGEQRLRKKDELFQSHIDDALSKMEDEEVNLLIKYADKF--------- ->tr|A0A098B5G3|A0A098B5G3_DESHA MarR family transcriptional regulator OS=Desulfitobacterium hafniense GN=AT727_20975 PE=4 SV=1 -------------------VRLLESIKKFRQLSLNFRGNgEIPHREIMMLKLIKHHSgegGITISSLSAHLEISKPAVSQMINSLEDKNYVERITPKSDRRMVYVRLTELGEEALGVAFHEMQKKLEIYLEKMGEEDMATLIALLDKL--------- ->tr|A0A161YU68|A0A161YU68_9GAMM Uncharacterized protein OS=Marinomonas sp. TW1 GN=OA79_07785 PE=4 SV=1 -------------------------------------------VDWRMLFLLALRPGATAAEASKTFGVDKGTVSRSVSRLTKGGLIVSGDLHANGRSRGLFLSSSGREMHDQLLAATLDQHHFLMKGFDEAEVKVFCDFLLRFTANLEDLS- ->tr|A0A0M4GRM9|A0A0M4GRM9_9BACI Uncharacterized protein OS=Bacillus sp. FJAT-18017 GN=AM500_17370 PE=4 SV=1 --------------------------------------------------RLQEEQG---aarvSDLSSGLDILLPNMTKLLKEMEGQQLVEKYRPPIDKRVVQIRMTSQGEQYFNDRVLPYRNQVLKELDNLETADVETMIRTIHQIQDILHRVYA ->tr|R6RJQ5|R6RJQ5_9FIRM MarR family transcriptional regulator OS=Firmicutes bacterium CAG:424 GN=BN652_02031 PE=4 SV=1 --------------------------------------------------EITCKQE---sctvSNIRDRMQITMPSISKLIQELEALHMIEKEADREDRRFYQLKLTWEGTDCVKKHVLDFHKEWAKRLAYVENQKVEEAVNLFTELRNTMPGGEV ->tr|A0A1V8QE99|A0A1V8QE99_BIFLN MarR family transcriptional regulator OS=Bifidobacterium longum GN=B5780_1797 PE=4 SV=1 --------------------------------------------------HINEQNGQDIgtarvGDVSAFLGVTTPSITKLVGEMADLGLVVKHADATDRRAVTLTLTERGLDIRRIYVEEYRAHLSQLLGGLTVDQCETTVRTLTEALRLMQQDAN ->tr|A0A095BFE2|A0A095BFE2_LEUME Transcriptional regulator OS=Leuconostoc mesenteroides P45 GN=LH61_08450 PE=4 SV=1 --------------------------------------------------------------FADKAKISKPAATRIIHRFVAEKYLVKRPSTVDKRTSYLELSAEMKINCEKNRQLFDQVFLDSISVLTPEEQTVLHKIMFKINEKI----- ->tr|A0A094JPM3|A0A094JPM3_9BACL Uncharacterized protein OS=Thermoactinomyces sp. Gus2-1 GN=JS81_10410 PE=4 SV=1 ------------DNLIGLFHQIMALCHLLL--REELKKHHLTFSHALVLHFLNVKGASPLVEISKHLDIPLSSLSGMIGRLEEMGMVLRKRDQKDRRIVQIRLTDKSREMIDELSDSQRNKIYAhvKRLNLSSEEMERFIENMQRF--------- ->tr|A0A081BIE2|A0A081BIE2_9LACO MarR family transcriptional regulator OS=Lactobacillus oryzae JCM 18671 GN=LOSG293_120470 PE=4 SV=1 ------------------------------------KQANLTISEWELLNRVTA-ENNTQELLSKLMDLDTSTLSRQLKNLVTKEMLDKTATGKDHRQLIYDVTEKGDQAKASIQEQVQRLDTTIFEHWSDEEKQLLQILLNRLAKSVNR--- ->tr|A0A0R1Y958|A0A0R1Y958_9LACO Uncharacterized protein OS=Lactobacillus aviarius subsp. aviarius DSM 20655 GN=FC33_GL000504 PE=4 SV=1 ------------------------------------KNNQLTIAEWQLLQRIAD-GKNSQELLAEDLRLDTSTLSRQLSKLTTKAFVKISKVanqnnVKTRKSYQYHLSEIGQRVLSQMNTDFKEFGQKVFAQWTGEEKNFLKILINRLTQSMRQ--- ->tr|E0NDL9|E0NDL9_PEDAC Transcriptional regulator, MarR family OS=Pediococcus acidilactici DSM 20284 GN=HMPREF0623_0391 PE=4 SV=1 ------------------------------------YEMTGTVADWKMVNYVND-ARLTTLNLVELSGLDKSTVSRQLKHAIQHNFLQKQSNEIDQRKSTFTITDKGDTLRTYVNQKMAEFDRHLFDNWSEEESAMFQILINRVLKNALK--- ->tr|A0A0A1PMQ0|A0A0A1PMQ0_9BACT MarR family protein OS=bacterium YEK0313 GN=BN1110_04673 PE=4 SV=1 --------------------LAARRIARRLEQGMAEAGMPLA--QFWLMAQIASSPDDRLGALAGRMGLDPSSLSRNLKVIERRGWVEIALAEADQRRRVVWLTEQGARALEAALPAWHAAHEALAAAMPQ----GFGQGLSRL--------- ->tr|A0A158IVA2|A0A158IVA2_9BURK MarR family transcriptional regulator OS=Caballeronia cordobensis GN=AWB70_05457 PE=4 SV=1 --------------------RLSRLLTGLYNAKMKDVPLSIS--QYTLIVNIEALAPARVTEVAKALLMDRTSVTRLTEPLITRGLLMIEQSEEDRRVKNLTVTTKGRNALRASEQAWQEAQLAFYEAVGPEQWKLLRKTLRDT--------- ->tr|A0A1V6GYF6|A0A1V6GYF6_9BACT Putative HTH-type transcriptional regulator YusO OS=Thermotogae bacterium ADurb.Bin062 GN=yusO_2 PE=4 SV=1 ---------------------------------------NLKTSELFILLFLYLKGPKSMNQLSRFLNTTKSNMTALIDQMERRDLLKREHSKVDRRVIDVSLKAKGRQICEEASDGFNVLVQAFFKKVNKEDLPIISQGFMCLHRLATE--- ->tr|A0A1A0CUW7|A0A1A0CUW7_BACIU Putative HTH-type transcriptional regulator YdgG OS=Bacillus subtilis GN=SRCM101280_04193 PE=4 SV=1 ---------------------------------------HISREQADLLKILKVKGPTSPGSLAMYQNVHKSAISNRLKKLLEKGLVQWDDCpeKSDRRSKLINITPSGEHILEELDSAIFNALKPLIDDIDEEHLHSIIEIFTIL--------- ->tr|A0A060M3I9|A0A060M3I9_9BACI HTH-type transcription regulator OS=Bacillus lehensis G1 GN=BleG1_2531 PE=4 SV=1 ---------------------------------------DLSPEQLAVLIIIDLTGPLTSKEIAEYQRTHKSAVSNRLKKLQQKNLIQFKESDKDSRLKYVHFSEEGKAKMKAYQEEVHTYFTALFSDFEAQEVAQFYQLMNKI--------- ->tr|C4FBB0|C4FBB0_9ACTN Transcriptional regulator, MarR family OS=Collinsella intestinalis DSM 13280 GN=COLINT_03364 PE=4 SV=1 ----------------------------FCGHYMHFHGGGRSGQIPILCMLDRCGGTLSQQELGMRFEIKPGSLSEILSKMETAGLIERTRDTKDRRQLFVHLTDEGTRLAHLEHEKRDRFRRSAFAALTVEEQEQLAEMLEKIRVT------ ->tr|G1WKD2|G1WKD2_9ACTN Uncharacterized protein OS=Collinsella tanakaei YIT 12063 GN=HMPREF9452_01752 PE=4 SV=1 ----------------------------FCGHYMHFHRGGRSGRAPILCLLEKNGGTMSQQALGASFDLKAGSLSEILSKMEGGGLITRTRDRQDRRQLTVCLTEAGAEAARLETEARIRFRTRAFSNLTPEEQDQLADLLDRVKSR------ ->tr|A0A1X9TWY7|A0A1X9TWY7_9LACO MarR family transcriptional regulator OS=Lactobacillus delbrueckii subsp. delbrueckii GN=B9N98_09750 PE=4 SV=1 ----------------------------QMGMRYEKLHGGVRGQNRTLALLSK-NEGMKQVELARFARVRPSSISKVVDRLERYGLIERRRDNSDHRVFRLYLTEKGREQNKRNHSSWLGFVGDLMSPLSDDEKAEYLNILKKPDKQ------ ->tr|A0A0S3KCP1|A0A0S3KCP1_9ENTE MarR family transcriptional regulator OS=Enterococcus silesiacus GN=ATZ33_12005 PE=4 SV=1 --------------------------------------------------------------VSEKLSFTKPAISAMVKRLEGLDFIEKHQSSIDKRIYNLLITEKGKNIVEGDNSLYQQFTEKVRELTTEDQMKQFTCLLEKLTAQL----- ->tr|V5WH60|V5WH60_9SPIO Transcriptional regulator, MarR family OS=Salinispira pacifica GN=L21SP2_1497 PE=4 SV=1 -----------------------------------LEGEDVTSKQLFLMIVVGNFGEKGPtvTQAAEKAGSSYQNVKKLALHLERSGYLRIVSDEDDRRAKRLVMTRRAKDFWQQREQQDARNFMELFRDFRFGELEKFNEYLLRLESQIEKSIR ->tr|A0A1V6IMX4|A0A1V6IMX4_9EURY Transcriptional repressor MprA OS=Euryarchaeota archaeon ADurb.Bin023 GN=BWX56_00769 PE=4 SV=1 -----------------------------------LRKDDLTTKQWQLIAAIGKYFTYPPsiSEIAEVLSTTHQNIKQIALKLQEKEFIAIEKDQKDKRVLRLRLTEKNRRYWESNKDEDEAFIRSLFNSLTDNEIKELYYLLNKLEENINQMYD ->tr|A0A174ASP3|A0A174ASP3_9FIRM Transcriptional repressor MprA OS=Faecalicatena contorta GN=ERS852491_00823 PE=4 SV=1 -------------------------------------DEEITMKQWLLLAMAGTTEN-PMslTDLGRLMGCSRQNVKKIAHSLEQKGFLRLERREGDSRAVCVVLDEKVKAYTDRVGEMQQGVLKLLFRGFSDNETSVLYQGIMKLQENISEIEN ->tr|A0A1Y4FAJ7|A0A1Y4FAJ7_9FIRM MarR family transcriptional regulator OS=Blautia sp. An249 GN=B5F53_03105 PE=4 SV=1 --------------------------------------NEMSCKQWLLMSVLKAFDT-PPdlSTVAKAMGCSRQNVKQLARPLEQEGYIRLEKSKEDARSLCISYTEKGRQFSKENTAKGKFVHEAVFSEFSEDEIDIYYSLSIKMMNGIKHLEE ->tr|A0A0I9QG01|A0A0I9QG01_KLEVA Transcriptional regulator, MarR family OS=Klebsiella variicola GN=BN1200_880007 PE=4 SV=1 ---------------------------------------PHTWSTMLLLSAIDHaEDGITPGELARSEDFRTSNLATMLKGLEARGLIVRIKDSDDRRRVRVYLTETARQLLSENRRKRDEWLFKAMIdGLKQEEVDVLLKAGEIMK-------- ->tr|A0A0Q7KLR3|A0A0Q7KLR3_9ACTN Uncharacterized protein OS=Aeromicrobium sp. Root472D3 GN=ASD10_06945 PE=4 SV=1 ---------------------------------------DLTPTQLSVLGAICQLGEATPGAIAALERVQPPSITRTLASLVEAGMAIRTPHPDDGRQVLMSVSERGDAVLAEERDRRDLWLSHALDELTPAERRTLEEAAVLLE-------- ->tr|A0A1E7XVR0|A0A1E7XVR0_9PROT Uncharacterized protein OS=Acidithiobacillus ferrivorans GN=A4U49_03380 PE=4 SV=1 ---------------------------------------ALGLSQIGVIARLHQt-GPMTTADLARIEFMKPQSMGTNLSDLERLKLVQRERHPTDGRQVLYSLTQEGIEERNHRRSTKKAWLAGAMEi-LRPEELEILARVIPIIQ-------- ->tr|A0A097CRN5|A0A097CRN5_9ACTN MarR family transcriptional regulator OS=Verrucosispora sp. MS100047 GN=VASRM7_57 PE=4 SV=1 -----------------------------------------------------------------------------MTDLCAVAEVVADPPPSRRRP-ATRATRSGTPRRTAE--------------------------------------- ->tr|A0A1Q4ZPQ8|A0A1Q4ZPQ8_9ACTN Uncharacterized protein OS=Streptomyces sp. MJM1172 GN=AMK15_35180 PE=4 SV=1 -----------------------------------LEARASGLLHQSILKVLADLGPHARRDLAAQVDAPPAEASRVMDDLQSQGLVQALVVNVGGRQEVLALTAAGTAARATALDHVKGVQDVLLASLTKGERAQLHYLLRRV--------- ->tr|A0A1S8YPY0|A0A1S8YPY0_9ENTR MarR family transcriptional regulator OS=Izhakiella sp. D4N98 GN=BTJ39_06480 PE=4 SV=1 -----------------------------------VGDSQLTAVQFITLCALRDHGPSAQNDLVRFTAVDQATIRGVVERLKARDLVSLGPDPKDKRKVIVMLTTEGQRLTSQVTTNAMRISEMTYGQLNPAERIALVYLLRKM--------- ->tr|A0A0D8HCP0|A0A0D8HCP0_9ACTN Multiple antibiotic resistance protein MarR OS=Acidithrix ferrooxidans GN=marR PE=4 SV=1 -------------------------------------NRDIDMNTFWQLSPLR-sGVPLRPSEIANAIGLDSSTVSRALQKLEAQGLIERRIDPSDARAHLIALSAEGATVLEIVGNARREKIATVLSHCTHSEIPSEEGLIRNVDGAI----- ->tr|A0A1C4LC61|A0A1C4LC61_9ACTN DNA-binding transcriptional regulator, MarR family OS=Streptomyces sp. SolWspMP-5a-2 GN=GA0115242_112514 PE=4 SV=1 -------------------------------------GVPIDRSSLALLRALAAaPSPYRMGDLAEVLLVQASHVTRQARGLEEAGLVTTVKEPGDdHRVRRITITQNGRDVVARAEATGQLWLTGALHGFTQEQLSVAAAVIQRVTDVY----- ->tr|A0A1T4YLL5|A0A1T4YLL5_9MICO DNA-binding transcriptional regulator, MarR family OS=Agreia sp. VKM Ac-2052 GN=SAMN06295879_3549 PE=4 SV=1 -------------------------------------EVPVRDGTYPILT-TL-aSGEARSTDIAERAGVDRTTASRQLASLIAVGLVDQRTDNNDRRNSLLALTPRGVATADRISDNADDMLEQALADWSLSDREALARLLPRLLSAL----- ->tr|A0A1F4E7T4|A0A1F4E7T4_9BURK Transcriptional regulator OS=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960 GN=A2710_05040 PE=4 SV=1 ---------------------------------------------MDVLQTIFWSAGASRNALAQRLAYSKSKANAMVAALLDEGLLDEVGLQESSggrRAETLRLSETLG--------------------------------------------- ->tr|A0A1H0YKI7|A0A1H0YKI7_9MICO Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain OS=Leucobacter chromiiresistens GN=SAMN04488565_0955 ------------------------------------------SNQGALVEALRQRGALSKMQLSELTGLSAATVNRVLKGLIEHGFVAQAGTEESTggrPAVLFDVVPTAL--------------------------------------------- ->tr|A0A1Q8LRB4|A0A1Q8LRB4_9PSEU Putative ROK-family transcriptional regulator OS=Pseudonocardia sp. Ae717_Ps2 GN=Ae717Ps2_2218c PE=4 SV=1 ------------------------------------------RNRELVLSSIQQHPNVTRSQIAELLGLPRTTVTAAVASLVSDGRVEENPtRPTHRrgrPAMLLRASEAVR--------------------------------------------- ->tr|A0A126YM16|A0A126YM16_9BURK HxlR family transcriptional regulator OS=Burkholderia sp. PAMC 28687 GN=AX768_16725 PE=4 SV=1 -------------------------------------------SRWGVLVLMVLLDEQMcrFSDLRRKVdGVSEKMLAQTLQWLAADGFVVRTSYDVVPPHVDYRLTPLGKEVARQVSSLADWIEINLARIMGARA-------------------- ->tr|C7RS71|C7RS71_ACCPU Uncharacterized protein OS=Accumulibacter phosphatis (strain UW-1) GN=CAP2UW1_2608 PE=4 SV=1 ----------------------------------------------ELLRTLPANGeFFPQWEVKAalatqEKRFSDSRLSQLLGQIEDHGLIGHRKR---GKYKDWRLTESGQQVLAK---------------------------------------- ->tr|A0A0Q4I758|A0A0Q4I758_9SPHN LysR family transcriptional regulator OS=Sphingobium sp. Leaf26 GN=ASE85_12310 PE=4 SV=1 ----------------------------------------------------------SFSRVGREVHASHTTIARRLDLVEAHfgvRLFHRTTR-------RLVPTADADQLLVHVRTMLDALDL------------------------------ ->tr|A3JY52|A3JY52_9RHOB Transcriptional regulator, ArsR family protein OS=Sagittula stellata E-37 GN=SSE37_20572 PE=4 SV=1 -----------------------------------------------VIERLAR-GPAAVSDLHDGHDMALPSFLKHLNKLEAAGIVR---SIKTGRTRMVHIEPAPLAAAEDWLIRQRNIWEGRLDRL------------------------ ->tr|T3D7H3|T3D7H3_CLODI HxlR-like helix-turn-helix family protein OS=Clostridioides difficile CD160 GN=QEW_3633 PE=4 SV=1 -------------------------------------------------------------------ECSKKMLTQQLDFLIEQEIIVKKKRLVNNIvESTYFLSESGLLLLPVMEKMIM---------------------------------- ->tr|A0A1J4V5C8|A0A1J4V5C8_9BACT Uncharacterized protein OS=Candidatus Hydrogenedentes bacterium CG1_02_42_14 GN=AUJ18_06755 PE=4 SV=1 -----------------------------------------------VLKILAEKPAVSLLELkkkikltppltpphfyknGEGLGERKNyALARLIKNLVESGYAEMRQSD---NQSYLKITKKGKNKLNciklegdeaLVPRVWDGFWRIIILDIPEErknEREALRYLLKK---------- ->tr|D3F751|D3F751_CONWI Uncharacterized protein OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_0386 PE=4 SV=1 --------------------------------------KELSIGEWAVLALLCERPmhGYaiaaamaPDGEIGQIWSLGQPLTYRALSVMQRLELVEVNAFkPGDRAprRTELRANARARRMVSR---------------------------------------- ->tr|A0A0R2QSS2|A0A0R2QSS2_9ACTN Uncharacterized protein OS=Acidimicrobiia bacterium BACL6 MAG-120910-bin40 GN=ABR78_04190 PE=4 SV=1 --------------------------------------YEPSVLDQIVLAIIGEIPrhGFavskeleTDPSLAAVIRIRRPLVYRSINSLLNAKFIRETKVePGDQGspRVIYATTATGKSTTAK---------------------------------------- ->tr|A0A094QP44|A0A094QP44_9ZZZZ Uncharacterized protein OS=freshwater metagenome GN=GM51_12660 PE=4 SV=1 --------------------------------------QDAQLARDVVLALVVLTPrhGWavheelaPSGTIGRAWTLSRQLVYRAIDTLVADGFVKRATPkDG-GGadKVIVSPTAAGKRHVEM---------------------------------------- ->tr|A0A1F8L5Q4|A0A1F8L5Q4_9CHLR Uncharacterized protein OS=Chloroflexi bacterium GWB2_54_36 GN=A2X24_04360 PE=4 SV=1 --------------------------------------QAPLSTEYILLGLAAKGPvhGYdlhkqlgTLDGLSSIWRVKQSQVYALLDKLENMGYLHGEAVPGTAAvlRKQYQLTAAGQQAFEA---------------------------------------- ->tr|A0A069IL45|A0A069IL45_9BURK Uncharacterized protein OS=Cupriavidus sp. SK-3 GN=CF70_022220 PE=4 SV=1 ------------ESVLLALMDSVREWQRVLDQTL--SDVGLDYAKWILLRAIRQGEFVRHEPWLGPMLISAPQSESLLRTLHADRWIEFDPAG------QPFIPAGAVPRVERVWSGMKALHSVSVAPFSTEERTALTASLRRMKATLHDHS- ->tr|X1N2C2|X1N2C2_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_49809 PE=4 SV=1 -------------------------------------QLELNSRQIKAVAYLQKKGKIARSEYVKLTKCSPKTANNDLHEMLDKQLIKQKGGGKYTFYVLTHV-------------------------------------------------- ->tr|A0A0G0IIN7|A0A0G0IIN7_9BACT Uncharacterized protein (Fragment) OS=Microgenomates group bacterium GW2011_GWC1_37_12b GN=US39_C0019G0007 PE=4 SV=1 -------------------------------------QIALSERQMKLIEYLTEIGGAGMQDLKkQLKMVSEDTILRDLTKLIEKGILKKEGHTKASKYVVVTK-------------------------------------------------- ->tr|A0A1F5ZW50|A0A1F5ZW50_9BACT Uncharacterized protein OS=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_02_FULL_39_11 GN=A3D77_06145 PE=4 SV=1 -------------------------------------RNVLDNDELRLVDFAISLGRITSSDAVDILKVPKRTAQSKLKRLEDIKVLTKHGAGPATYYIVTPL-------------------------------------------------- ->tr|A0A1F5YFP7|A0A1F5YFP7_9BACT Uncharacterized protein OS=Candidatus Gottesmanbacteria bacterium RBG_16_38_7b GN=A2153_04225 PE=4 SV=1 -------------------------------------EKELLPHHQTIISYLKEKGFIKDRNYARLTNRAKATRILDFKKLMNMGIIERLGKGKNTYYTLKTS-------------------------------------------------- ->tr|A0A0C1GYN6|A0A0C1GYN6_9BACT Uncharacterized protein OS=Candidatus Protochlamydia amoebophila GN=DB44_GG00010 PE=4 SV=1 -------------------------------------EYKLSKRQKLALDCLLeRKENFSIRNYElLCPGINRRSLQRDLSDLIEKKLISQDGIKKASRYKVNRL-------------------------------------------------- ->tr|F8AMP4|F8AMP4_METOI Transcriptional regulator, PadR-like family OS=Methanothermococcus okinawensis (strain DSM 14208 / JCM 11175 / IH1) GN=Metok_09 ---------------------------------------------LLILYLLDKEDlhGYAlMQKLSELFINYkpsSGVIYPTLQGLKRSGYIEYVKFEADeksrnenknnenenenkknnHSKKLYRITDKGREYLKENDKKLKRIFEHInnINEFYDLGGKSLKEAMTIVIKEIPNLSE ->tr|E0SQI5|E0SQI5_IGNAA Transcriptional regulator, PadR-like family OS=Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1) GN=Igag_1439 PE=4 ---------------------------------------------YLVLYAIDNlKKayGYEiRRFIRSILKLYtpsTGILYPTLHELEKEGILMSYKEG---RRRVYMLTEYGRKLLERDREKIYSYVGKLryAtEILEKLDIDKLINIVKVLWENNIVLSP ->tr|E0SQM7|E0SQM7_IGNAA Transcriptional regulator, PadR-like family OS=Ignisphaera aggregans (strain DSM 17230 / JCM 13409 / AQ1.S1) GN=Igag_0252 PE=4 ---------------------------------------------LLILKILSESPmhAYGiLKRLREITGHEelsVGVLYPVLRTLINKGLVDIRIDRVDgEERKVYYVTDKGKKLLDERASSVDEALRVAnrFKILKSIEVDRVFRTIRSLFEIADSLSE ->tr|B8D3Z1|B8D3Z1_DESA1 Transcriptional regulator, PadR-like family OS=Desulfurococcus amylolyticus (strain DSM 18924 / JCM 16383 / VKM B-2413 / 1221n) ---------------------------------------------LLILDMSRGGRihGYYlLKKIREETGLPvnPGLIYPLLKGMVEKGLIKAEESFEKgRRKIVFRITEKGEKYLEENKQELEIARKYFekLKLAKEVGLTKLVARLIRIFEKIDQLTP ->tr|A7NQR4|A7NQR4_ROSCS Iron (Metal) dependent repressor, DtxR family OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) GN=Rcas_3874 PE=4 SV=1 -----------------------------------------SVEMYLVMTALLRSapdQPVPLSLLASKLGVSQVSANEMCHRLEERGLLSYQPY------KGVTLTPDGEEWAQRILSRRRLWVIFLVEnlGIDPEEADTLACQLEHI--------- ->tr|A0A0N2QP32|A0A0N2QP32_BORPT LysR substrate-binding domain protein OS=Bordetella pertussis H921 GN=L548_2381 PE=4 SV=1 ----------------------------------------PSFAQLGVFHAIMITSSVSRA--ARLMGMTQSAASKMLRQLEDDTGLRLF----ERQHQRLVPTPHAQGLQDSVEQLYGAYGV------------------------------ ->tr|A0A1M6VZJ8|A0A1M6VZJ8_9BACL Transcriptional regulator, LysR family OS=Alicyclobacillus sp. USBA-503 GN=SAMN05443507_1258 PE=4 SV=1 ----------------------------------------KRLELYQALVQIVENETLVQA--AQVLNTTQPTLTRQLQQLEHRlgvRLFDRIGR-------RLVMNHAGELAYQYAKRILQTEER------------------------------ ->tr|A0A0U5D108|A0A0U5D108_9EURY Homolog to phage PhiH1 repressor protein OS=Halobacterium hubeiense GN=HHUB_3508 PE=4 SV=1 ----------------------------------------MTPVDRDILERLWNERNrdlqLTPSMIAENVDWGHQAVREHVLTLHEHDLIEYA----DEDRGVYKLSKRGRKWLE----------------------------------------- ->tr|A0A1Q9NWB6|A0A1Q9NWB6_9ARCH Uncharacterized protein OS=Candidatus Heimdallarchaeota archaeon LC_3 GN=HeimC3_09400 PE=4 SV=1 ------------------------------------------------------GESMFVSKLAKNyqekfelnglKKISRSAIRKHIEILKEYGFIKPVNE--GGKPEFLQVTEIGMKAIKKFEK------------------------------------- ->tr|C9MSE6|C9MSE6_9BACT Fic family protein OS=Prevotella veroralis F0319 GN=HMPREF0973_02565 PE=4 SV=1 ---------------------------------------KWSikpslaAKLVDIIYFANNHQELTTELITREFQLTPTTAKRYLRQLVSFGFLQSEGANRNRKYRALGN-------------------------------------------------- ->tr|A0A1V6BXV5|A0A1V6BXV5_9BACT DNA-binding transcriptional activator FucR OS=Bacteroidetes bacterium ADurb.Bin139 GN=BWX93_01205 PE=4 SV=1 ---------------------------------------KISSRQAGIIDLIRIDSSVTTDDLARKICVSSKTIKRDIAVLKQQGILLREGSDKKGKWIISVP-------------------------------------------------- ->tr|A0A1V5S0Q0|A0A1V5S0Q0_9BACT Fic/DOC family protein OS=Bacteroidetes bacterium ADurb.Bin302 GN=BWY47_01161 PE=4 SV=1 ------------------------------------------vnssDMDSQLLTLIKEHPEYTYEEYAQKLNVGRATIARHIKKLS-GTMIERIGSDKNGYWVLIK--------------------------------------------------- ->tr|A0A1C5QNU2|A0A1C5QNU2_9FIRM HTH-type transcriptional activator CmpR OS=uncultured Ruminococcus sp. GN=cmpR_2 PE=4 SV=1 ----------------------------------------MDISKYALFADVADTGNFTKS--GERMGYTQPGVSHILKAMESE--FGFPLFVRTKQGV--VPTHNAEAILPLVRQLLAVNEQLE---------------------------- ->tr|A0A1V1YNW0|A0A1V1YNW0_9ACTN LysR family transcriptional regulator (Fragment) OS=Streptomyces sp. WAC00263 GN=BOG92_22825 PE=4 SV=1 ----------------------------------------LLAPRLAYFAGVARTEHVTRA--AQEMRVPQSTLSRAMVRLEQD--LGVDLFARRGRTV--SLTPAGRTFLSSVERALAEIERAA---------------------------- ->tr|A0A1M7REE0|A0A1M7REE0_9ACTN Transcriptional regulator PadR-like family protein OS=Cryptosporangium aurantiacum GN=SAMN05443668_110301 PE=4 SV=1 -----------------------------------MRDVEMTLAIARLLKAFLEDPLRPrhGYDLMRSTGFASGKIYPLLAKLQTAGWLTRERESVDpaavgrPARRLYRLSDEGTQAAWHALD------------------------------------- ->tr|A0A0K2SGW4|A0A0K2SGW4_9FIRM Uncharacterized protein OS=Limnochorda pilosa GN=LIP_0410 PE=4 SV=1 -----------------------------------------------ILRTMHEEGACTRTSLARTTKMSPATVSRIIGQLMGHGIVReesRIPSSAGRKPVLLRIDYAKLPIV------------------------------------------ ->tr|A0A0M0TMJ7|A0A0M0TMJ7_9FLAO AsnC family transcriptional regulator OS=Flavobacterium sp. VMW GN=AKO67_09385 PE=4 SV=1 ---------------------------------------SLDEFDINIIKELEKDGRMAFSAIAANLKISNTMVHQRINRLMEQGIIGGIKPIIQEKKIGFDWAS------------------------------------------------ ->tr|A0A0Q4R1A8|A0A0Q4R1A8_9SPHN PAS domain S-box protein OS=Sphingomonas sp. Leaf242 GN=ASF09_19090 PE=4 SV=1 -----------------------------------------------VAIYLAEAEGrvVGVERLASETRMAPSTTRRWITALQQEGIIWDDSNVVA----DVQFTQSGITRMEGMLASVFQ--------------------------------- ->tr|A0A0Q5UKX6|A0A0Q5UKX6_9SPHN Uncharacterized protein OS=Sphingomonas sp. Leaf198 GN=ASG20_09320 PE=4 SV=1 -----------------------------------------------LSVYVAEAESriATVDSVASQLGLNRATLDRWIRVLEAKSLVDPPDSMRE----ALQLTRSGIDDVERLLSTRSL--------------------------------- ->tr|A0A0G1MTY6|A0A0G1MTY6_9BACT Transcriptional regulator, TrmB OS=Candidatus Peregrinibacteria bacterium GW2011_GWA2_44_7 GN=UW70_C0034G0016 PE=4 SV=1 -----------------------------------LREIGFSDKEIKVYLAALKLGMQPASVLAKHLKMNRVTTYVICKKLIEKGVANALTRNN----------------------------------------------------------- ->tr|A0A0G0QY35|A0A0G0QY35_9BACT Transcriptional regulator, TrmB OS=Parcubacteria group bacterium GW2011_GWB1_40_14 GN=UT82_C0032G0017 PE=4 SV=1 -----------------------------------LENIGLSRKEAKIYLALLDYPESTLADIVRKTRMPRMTCHSILEKLFTGGFIDIIIKRK----------------------------------------------------------- ->tr|A0A1G2AQR1|A0A1G2AQR1_9BACT Uncharacterized protein OS=Candidatus Kerfeldbacteria bacterium RIFCSPHIGHO2_02_FULL_42_14 GN=A3B74_00095 PE=4 SV=1 -----------------------------------LKGLDFTDKQIDIYLYLLREVRASAKQIYESLHLNKVTAYKVLDELVEMDVIGVIHGED----------------------------------------------------------- ->tr|A0A1F5WQD6|A0A1F5WQD6_9BACT Uncharacterized protein OS=Candidatus Giovannonibacteria bacterium RIFCSPHIGHO2_12_FULL_43_15 GN=A3F23_00640 PE=4 SV=1 -----------------------------------LKKLGLSEGEAVAYSYLLENGESSVGQMIKKLPIKRGNLYNVLRGLVFKGLAEEFKKNK----------------------------------------------------------- ->tr|A0A1F8H881|A0A1F8H881_9BACT Uncharacterized protein OS=Candidatus Yanofskybacteria bacterium RIFCSPLOWO2_02_FULL_47_9b GN=A3I39_01770 PE=4 SV=1 -----------------------------------AEVFNMSLNEAKVYLALNNQGSSMVSRVGKSANLPRTAVYPPLMSLVKRGFVGTTVSGK----------------------------------------------------------- ->tr|A0A1X2BVQ3|A0A1X2BVQ3_9MYCO Transcriptional regulator OS=Mycobacterium saskatchewanense GN=AWC23_22395 PE=4 SV=1 -----------------------------------LVEAGLEPKEARFYLAALSMDSATVAQVAEASQISRTNAYDIAKRLAQRGLLSLIEGGS----------------------------------------------------------- ->tr|Q1GES2|Q1GES2_RUEST Transcriptional regulator, IclR family OS=Ruegeria sp. (strain TM1040) GN=TM1040_2112 PE=4 SV=1 ---------------------------------------------IEILETLAREGAMSLADLHRATGLPKSTLRRLLQTLIARKIVRRSLA--DKLyRTLVVFPDISGEVMPKGMLHISEAAIPRALALTKE--------------------- ->tr|H5X8L5|H5X8L5_9PSEU Transcriptional regulator OS=Saccharomonospora marina XMU15 GN=SacmaDRAFT_3156 PE=4 SV=1 ---------------------------------------------LRVLRVLQEMRAASLHDLHLATGIPKASLTRILHTCHREGLVWQRMA--DGAfLPSHIQQRRA-KIDD--AEWLVEIASPVLKRLCEQ--------------------- ->tr|A0A089J565|A0A089J565_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL P4-0081 GN=P40081_18135 PE=4 SV=1 ----------------------------------------------QLEYFLAVCEEMHFTRATDKVRISQPSLSQQIRNLEYEVGTPLF----DRIGKKIALTEAGKILKHHSQNIFYELNQ------------------------------ ->tr|F7SBJ4|F7SBJ4_9PROT Uncharacterized protein OS=Acidiphilium sp. PM GN=APM_3852 PE=4 SV=1 ----------------------------------------LTAKRWDILQAMTGHGEMAIREVARQVDRDVKAVHGDVQALLTAGVLDRTDS------------------------------------------------------------- ->tr|E7N4Q4|E7N4Q4_9FIRM Fic family protein OS=Selenomonas artemidis F0399 GN=HMPREF9555_01999 PE=4 SV=1 -------VNAAVSGTEKNLREKKDRYDVYYSRIQ--K-l-EVDRTLKELYDVLLQAtifsgaG-VSKKELMRMLDKSENTITARMKAMPS-GVlRENRT----VRPFTYALNLKVFDEP------------------------------------------ ->tr|S4HAS7|S4HAS7_GARVA Fic family protein OS=Gardnerella vaginalis JCP7275 GN=HMPREF1572_01283 PE=4 SV=1 -------IVKAQGEVFENINLQLKQTIYCMDKLFEFSKkTAISKVQYEVMTILLQNklfsynPtPMTRKQLSEYVGnaigeqVGERKIVSALNGLIELEMVDSIG----ERPLRYELSKKANEMF------------------------------------------ ->tr|W4N9C4|W4N9C4_9BIFI Cell division protein Fic OS=Bifidobacterium moukalabense DSM 27321 GN=BMOU_1172 PE=4 SV=1 -------IERAQTSLIDELGVKIDQLGKAGDLRDELENel-KLSHNATCLLYAVMQEelfdttKSMTLEEAGADLMLTKQTMRKYVEELDRAGLIEFTG----RRPLRFGASESLRGKM------------------------------------------ ->tr|T2I184|T2I184_BIFLN Fic/DOC family protein OS=Bifidobacterium longum subsp. longum CECT 7347 GN=BN57_893 PE=4 SV=1 -------VADAQKKLIDDLSEKGYMLLHAVNRL----EslkeeRQWDDVEANIIAVLVQEelfgesPhRVTRRQLGEGLGLGRKKITQGLGSLEETEAVSHKg-----TRPAFYSLTDEIRARL------------------------------------------ ->tr|A0A0H0YL18|A0A0H0YL18_LACCA Uncharacterized protein OS=Lactobacillus casei GN=AAW28_08645 PE=4 SV=1 -------IETGQKDIIAALKQSQVKLEDWFKRILA---ADFTDHQKAILAYLIQPylfgsrE-NSTmddNALKELLSrqgfngrtYSQVSIKKSIDQLEKDGWIELVK----HRPKIHAVSQRFIAYM------------------------------------------ ->tr|D5P131|D5P131_CORAM Fic family protein OS=Corynebacterium ammoniagenes DSM 20306 GN=HMPREF0281_02321 PE=4 SV=1 -------LVDAMEELLDSLVKKNSQLSIMREQVATLISedpsvdDALDEKESDILFLLGQVhlfgprSGMTMDELCQVMGRTRRSLRSVTVRLRERGLIRELK----KSPLVFALTDEAIELV------------------------------------------ ->tr|A0A0U1A2M9|A0A0U1A2M9_9MYCO Filamentation induced by cAMP protein fic OS=Mycobacterium abscessus GN=ERS075547_00755 PE=4 SV=1 -------IAEAQHRLLLDLSDRRQKIDTVAACIRVLVEdeqfplniglireaepPVDPKDIGVILFVLGQAhhfdvnRAVKLKTLADAMDRSIQFARPRLQRLDDAGIIETVT----RKPLRFRLTQRGASLL------------------------------------------ ->tr|A0A086Z272|A0A086Z272_9BIFI Fic family protein OS=Bifidobacterium actinocoloniiforme DSM 22766 GN=BACT_1326 PE=4 SV=1 -------IQEAQDDFMKAFGRQLEERTQISPLC----EsigreRGLTGPATRILESVFREavlgtrKGVGLGDLSQELGRSKQSVRIHVGELLEKGLAVYTk-----RRPLMITVSHAALGRF------------------------------------------ ->tr|A0A0F4LNB3|A0A0F4LNB3_9LACO Fic family protein OS=Lactobacillus apis GN=JF72_12890 PE=4 SV=1 -------LSDGQDEVIDQLQKARYRLDYVKKELEK---RKYSIVKFNELYIYSQAylfndfE-GSIedRELFELFKqdhISRRKFKEGLAELQNEGLIETVK----AKPLKRRITAKFLEQI------------------------------------------ ->tr|X8ITT0|X8ITT0_9FIRM Fic/DOC family protein OS=Mogibacterium timidum ATCC 33093 GN=HMPREF0581_0975 PE=4 SV=1 -------IKESAINLKAGLTEKSERLNVLKKGFLGNL-pn-GQEGKYTDLYYFLLQAslfseiG-ISTKSLIENLNVSRPTLQKRLHEIDENNLlVTEIE----DRNKFYKLNLDTLVEK------------------------------------------ ->tr|K0YID9|K0YID9_9ACTN Uncharacterized protein OS=Slackia piriformis YIT 12062 GN=HMPREF9451_01729 PE=4 SV=1 -------VLTGMERLREALAERDVNLRKYEALAWELYGe-QGDKSSYELMRILIVArlfalyG-VMSDELCEVLDITKPTLQRRFRPLKDAGLvRVERV----GHKVYYACELDELERR------------------------------------------ ->tr|U2SS80|U2SS80_9FIRM Fic family protein OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=HMPREF1985_01901 PE=4 SV=1 -------IQKSIHRVHDILQEKGKKLFSLEKAVKASP-d-IPSQKERKIYDILLQAylfsdeG-ATVEEIAHTLGQSTRTIRTHLTRYPA-DHiEVDPS----HKAHRYKLSEHFVQKL------------------------------------------ ->tr|F8DZ17|F8DZ17_CORRG Uncharacterized protein OS=Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026) GN=CRES_0597 PE=4 SV=1 -------LHEAQLDILTSLLEKRSLLESVHRRLSNEK---LSNYSHGILYSLAQVtlfgseETLTLSEIVSVSPYSWNTLRKEAELLVKKQLLIPVS----KRPLTYALAPVARKFL------------------------------------------ ->tr|T4C0E2|T4C0E2_CLODI Fic/DOC family protein OS=Peptoclostridium difficile F501 GN=QOE_2572 PE=4 SV=1 -------IVSAMESMRNSLRELRNMLEEGERMAEIVFA--KDEKAIEIASVLVTAalfafnG-ITMAELTYTFDASRQTMYKKLAPFKERGVlVAQKE----GRKTYYRMDLDALRRL------------------------------------------ ->tr|A0A0Q1DVX0|A0A0Q1DVX0_9CORY Adenosine monophosphate-protein transferase SoFic OS=Corynebacterium sp. NML 130210 GN=Cocul_01137 PE=4 SV=1 -------VHTAQRNLSAEISERKQSLDTLWSSVEQLSNr--FEEQEMAILFVLGQAhlfnseSGILHRTVVEYVPTGDRQTRRWTTRLQERGLVELRG----ERPLRYGLTAESRNLL------------------------------------------ ->tr|R7AZC4|R7AZC4_9FIRM Uncharacterized conserved protein OS=Ruminococcus sp. CAG:379 GN=BN633_01571 PE=4 SV=1 -------IRTSSESLNASLLKRLEKMTFFRNQLLKRF-pn----DRHFRVLHILMLNtlfgyrG-LTLPELAAACGMDEPLTAVLLQTLAtQTPLvVLYRE----GEHTMYEVNLERLAEI------------------------------------------ ->tr|D7BPH5|D7BPH5_ARCHD Filamentation induced by cAMP protein Fic OS=Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 845 -------IRDTQQDLILQLEEALKRLLSVQMRLDQCN---VDSDCSTILWILAQAelfsggTTMERRELEQYVEKSTPTINRYIKQLVADGWVEIVA----QRPVTIRLSDEGAPRL------------------------------------------ ->tr|A0A0R1WK16|A0A0R1WK16_9LACO Fic family protein OS=Lactobacillus nantensis DSM 16982 GN=FD31_GL002284 PE=4 SV=1 -------ILEGQISVLEKLNELLDLLNKYFAELKEILNvnDTNNDLEFNLLFVFIESklfnvdS-SLGvkdTPLINMLYkrdtrlYKKVKIREIIKKYEDSGILVKVG----QKPLQHEIDLEKLFGD------------------------------------------ ->tr|A0A1E9U2K1|A0A1E9U2K1_9CORY Cell filamentation protein Fic OS=Corynebacterium sp. HMSC074C11 GN=HMPREF2614_01865 PE=4 SV=1 -------ILNAQQYLLEELQMKSYQCERLEQRIAELSNspervlpVSLTGNEIGTLYVLAQGrlfgpeYGIKLEHVADTVGKEKRTARKYLAELEAAGLAMPTS----RRPLRFQLAPAGVDLL------------------------------------------ ->tr|A0A1F1V104|A0A1F1V104_9CORY Uncharacterized protein OS=Corynebacterium sp. HMSC08F01 GN=HMPREF3171_00860 PE=4 SV=1 -------LIDAQRDLEESLDQKHFQLHSLHEVLSSVD---RDEYECDLLYLSAQAylfspdLPFSLKDAVSAIGRSWNTIRPVAEKLEAEGLIQSAS----KSPLTLELTAQGREYL------------------------------------------ ->tr|A0A1C4H5Q0|A0A1C4H5Q0_9BIFI Fic family protein OS=Bifidobacterium commune GN=GA0061077_1140 PE=4 SV=1 -------IQIAQRRFNDNLNEKELALNTATNAM----IhyaaeQRLDPMSTDILSILIQQrlflrrEaELTRAMLAGYENVGQARIRSKLELLTRKDLISTVg-----KRPICYQLSNHACELF------------------------------------------ ->tr|A0A172S096|A0A172S096_9ACTN Fic family protein OS=Denitrobacterium detoxificans GN=AAY81_09720 PE=4 SV=1 -------IREAQLAIIKRLEACARKLDELDGIM----GnitsnVKLRSKEAQVIHLLLQYkafglfGDASVQEIADYLGVGKQQARKYIAALEERGICQKLnS----YNPITFKLTDEFIATY------------------------------------------ ->tr|A0A1Q6E1J9|A0A1Q6E1J9_9ACTN Uncharacterized protein OS=Eggerthella sp. 51_9 GN=BHV62_05600 PE=4 SV=1 -------VVDAMESMLDSLQAKQSDLADAVGAVNRAIAtk-EEDAGLWRVAFILAQAdlfsenG-ATTEELCAAAEMSEPTMARKRKLIKELGFlRETRK----GRQRFYSLNLQKMG-------------------------------------------- ->tr|A0A1Q6RGK3|A0A1Q6RGK3_9FIRM Uncharacterized protein OS=Firmicutes bacterium CAG:24053_14 GN=BHW36_09575 PE=4 SV=1 -------IEKSMSALRDALEKRSALLTHYS-LNIGSL-pd-ADSEIIYELYSVLIQArlfsenG-VSMGELCAHLNRSGETVRKKLAVVKNSGLlITKTV----KREKFYGIDLELIDNF------------------------------------------ ->tr|A0A1Q9YNN2|A0A1Q9YNN2_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=BO223_00070 PE=4 SV=1 -------LESALKHEIVKLESQLEKYEQYLSKLNNT---SLKPAEKTFLETLLAAslfslyG-ISKQQMIQITQMSQSWVDKTLKKHR--DKlNVRRE----GHAKWYSMNKEFLATL------------------------------------------ ->tr|A0A1Q6NWC6|A0A1Q6NWC6_9FIRM Uncharacterized protein OS=Eubacterium sp. 45_250 GN=BHW21_02235 PE=4 SV=1 -------VDISMKQLYDEIKNKLDKFNFYG-DLCPKL-pn-ADHKDIERLYYVLIQAalfsenG-ISQNELESFFNVSYSSVRNKLSSIPA-DLlIKNTR----ERHAYYMLDLDKVDIM------------------------------------------ ->tr|A0A1V5HVM4|A0A1V5HVM4_9BACT Adenosine monophosphate-protein transferase SoFic OS=Tenericutes bacterium ADurb.BinA155 GN=BWY98_00660 PE=4 SV=1 -------IDSGYDDTLAYLQKKQNLAEQLRAKTS----pf-VKTAAEKRLMEALLEAsvygdfG-LTVLALSEAGKVGSATVNRFLAKLKKNGVlWIRRF----GKKDYFLFPSPNTSL------------------------------------------- ->tr|A0A229W136|A0A229W136_9BIFI Cell division protein Fic OS=Bifidobacterium sp. Tam10B GN=Tam10B_0037 PE=4 SV=1 -------VNDAQRRIIDDLSEKYGAFERAKAVL----YelsreRGWSDDQVDIVGVLIQEelfgtpPhRVTRPQLQNGLKFGRKRVNTALDPLVESGAMVTMg-----MRPVRYSLADGMRRLL------------------------------------------ ->tr|A0A1Y2SZH8|A0A1Y2SZH8_9BIFI Uncharacterized protein OS=Alloscardovia macacae GN=B9G54_04580 PE=4 SV=1 -------IETAQTSLILHLREKLTILESATQFM----TqhfTDLNTTERNTLEILLQEhlfnryTsGLTRTDIMNALDVGHKKVKNTLDHLAALGYITIEg-----KRPIRYSASTKLRDEL------------------------------------------ ->tr|A0A0S1YFH6|A0A0S1YFH6_9ALTE Transcriptional regulator, Crp/Fnr OS=Alteromonas stellipolaris LMG 21856 GN=AOR13_64 PE=4 SV=1 ----------------FLTRNLAIKLHATLERLDDILRLPTHVQLAKLIYQTSVAQassvetksvqaslsqtstavALRQSDYAERLGVTVLTAHKALNKLVSLSLIRK---------------------------------------------------------------- ->tr|A0A0G3V621|A0A0G3V621_9ACTN Uncharacterized protein OS=Actinobacteria bacterium IMCC26256 GN=IMCC26256_112034 PE=4 SV=1 -----------------------------------------RLDLAPVSSGIVVEN--ELLHTLRLVGSSLDTGGSVSDSIVASGFALRR-------KDRLLLTPSGRVAAEEAAR------------------------------------- ->tr|A0A0M8PRS5|A0A0M8PRS5_RHORH Uncharacterized protein OS=Rhodococcus rhodochrous KG-21 GN=Z051_01280 PE=4 SV=1 -----------------------------------------VPHEINLLQALRLKGRIEIEALPRTLAADPASVDPLVTAHVEAGHCIHK-------GNFLRLTADGKQTLVEWTT------------------------------------- ->tr|A0A0N9HNM9|A0A0N9HNM9_9PSEU Uncharacterized protein OS=Kibdelosporangium phytohabitans GN=AOZ06_18105 PE=4 SV=1 -----------------------------------------VSIAFDVLHALAVKGMAQAGPLAVSSGVSGDELNEELARITEEGLANHMA-----GRGLWRITPDGRAKHAQLLH------------------------------------- ->tr|A0A178WSE4|A0A178WSE4_9PSEU Uncharacterized protein OS=Amycolatopsis sp. M39 GN=A4R44_08061 PE=4 SV=1 -----------------------------------------EKTDYDVLNTITLKKMATPAAVVRASGRDTAEVETAFERLAAQGLVAVA-------SGAALPTDEAEPALLDAAA------------------------------------- ->tr|A0A163Z9K0|A0A163Z9K0_MYCKA Uncharacterized protein OS=Mycobacterium kansasii GN=A4G26_11235 PE=4 SV=1 -----------------------------------------MADELTILRLVAIKGRVPTELVAGSLGVDEERAQALLDDLVEWELVKQT-------SMGYRVTAAGRARCTEFVA------------------------------------- ->tr|A0A0Q9QR53|A0A0Q9QR53_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil777 GN=ASG88_20930 PE=4 SV=1 -----------------------------------------MELRDLVLHALTVKKSGTADQIAEFLGRDSGEIATTLSAAAEDGLVAGG-------AGIHMATPAGRQVLDELYP------------------------------------- ->tr|A0A076F085|A0A076F085_RHOOP Uncharacterized protein OS=Rhodococcus opacus GN=EP51_46300 PE=4 SV=1 -----------------------------------------LDPYELTVHTLTLRQLGSAEQLAEINALPVADVETALEKAVADGAVMAA-------RGNYMITPAGREFLDGVYP------------------------------------- ->tr|A0A0A1VC53|A0A0A1VC53_9BURK Uncharacterized protein OS=Acidovorax sp. MR-S7 GN=AVS7_00918 PE=4 SV=1 -----------------------------------------NAEQHLVLHGLAIKKYAHPDAIASLLDLPPGRVKQVVDEGVAKGTVIDV-------GGKFAVSPAARLSLHANYS------------------------------------- ->tr|A0A1B1H0F7|A0A1B1H0F7_9NOCA Uncharacterized protein OS=Rhodococcus sp. 008 GN=AOT96_32130 PE=4 SV=1 -----------------------------------------PIEAFELLHLLRIRGRVAADQLDTDDAVIEALSETDLIRMTERGAVLTS-------KG---------------FQ------------------------------------- ->tr|A0A1Q7D666|A0A1Q7D666_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_2_20CM_2_66_6 GN=AUI15_15355 PE=4 SV=1 -----------------------------------------ADVPDSIVWAMTIKGSAPLDGLASAVGSNPERVQAILNRLLKEGLVERA-------GSSYRLSSKGKLKGRQLLA------------------------------------- ->tr|A0A1V0AHF6|A0A1V0AHF6_9ACTN Transcriptional regulator OS=Nonomuraea sp. ATCC 55076 GN=BKM31_55890 PE=4 SV=1 -----------------------------------------SPLDLLVLHAVRITGYADTPAIAHRYGLDAAETKEVLLDAQAYGWVQHTVAF--GDTGGWSLTERGKAENERLLA------------------------------------- ->tr|A0A1V3ZXX9|A0A1V3ZXX9_RHORH Uncharacterized protein OS=Rhodococcus rhodochrous GN=GQ85_00460 PE=4 SV=1 -----------------------------------------EKDEFEVLHGLRIKGMTQPEEIAEATGLEVDLVTEVLDGAVAQERARHRTG---GKVQGYMLTASGRDRHQSLRA------------------------------------- ->tr|E9T1Q3|E9T1Q3_RHOHA Transcriptional regulator, ArsR family OS=Rhodococcus equi ATCC 33707 GN=HMPREF0724_12100 PE=4 SV=1 -------------------------------------------------------GEHSVSALAEKYDMSFAAVQKHVSVLQNAGLLTKRRR---GREQLASGDVAAVRSVASMLTELEDVWRGRIARIDE---------------------- ->tr|A0A1E3S2Q6|A0A1E3S2Q6_9MYCO Transcriptional regulator OS=Mycobacterium holsaticum GN=BHQ17_01185 PE=4 SV=1 -------------------------------------------------------RERSVTALAAKYDMSFAAVQKHVAVLERAGLISKRRE---GREQLASGDVEAVHSVASMLTELEDVWRGRVAAIDD---------------------- ->tr|A0A1T5AJ03|A0A1T5AJ03_9SPHI DNA-binding transcriptional regulator, ArsR family OS=Pedobacter luteus GN=SAMN05661099_0771 PE=4 SV=1 -------------------------------------------------------QALTPNAMAEKFDMTRQAVSKHIKVLHECELIKPEQS---GREIYYHFNPKKMREFDNWLAQFRHNWEVQFNQLDN---------------------- ->tr|A0A1V0N4T6|A0A1V0N4T6_9EURY Transcriptional regulator OS=Ferroplasma acidiphilum GN=FAD_1280 PE=4 SV=1 --------------------------------------------SLRILYILNLED-MTGYGLSRKLYNsatgkniSNGALIPVLNRLLSDNFIDFSVR---NGKKYYHLTEKGKKFVGNVLDLNEEVRDQAIFD------------------------- ->tr|A0A0D6ULZ8|A0A0D6ULZ8_STRGR ArsR-family transcriptional regulator OS=Streptomyces griseus GN=BF14_5776 PE=4 SV=1 ----------------------------------------------RILRHLGAAGPATSTTLAAALGENTGTLSYHLRMLERSGLIEDIPERSTGRERWWRGVRGlDIRRPPQGelTEAERAMSAELDRMRMEEDVDLARQFTA----------- ->tr|U5WBV5|U5WBV5_9ACTN ArsR family transcriptional regulator OS=Actinoplanes friuliensis DSM 7358 GN=AFR_41700 PE=4 SV=1 ----------------------------------------------QLVTWLQRHGSATSADLAVEFDADRGATSYHLRQLARFGFVEEDTERSAGRRRYWRAIPQDVRLPRGPaDPELALVADELGRQWMERADRDLTAYLS----------- ->tr|A0A1H1R1J9|A0A1H1R1J9_9ACTN Helix-turn-helix domain-containing protein OS=Jiangella sp. DSM 45060 GN=SAMN04515669_0774 PE=4 SV=1 ----------------------------------------------TLLRLLREDGPATASSLGERIGQSSGVTSYHLRTMAEAGLVVEDASLGNRRDRWWRAAHEatTFSFRVPGqagDTEHLEVaeqyLRMVAQVGYERVLSWISTLVE----------- ->tr|A0A242K0P0|A0A242K0P0_9ENTE Uncharacterized protein OS=Enterococcus sp. 9E7_DIV0242 GN=A5888_003823 PE=4 SV=1 ----------------------------------------------------------NVLRAAEHIYIGHGTASTRIMNLERKlgvILLERQKG-----VRKTVLTSEGESFLPIAQQWAALWSD------------------------------ ->tr|U2TT25|U2TT25_ACISB FCD domain protein OS=Acidaminococcus sp. (strain BV3L6) GN=HMPREF1246_1747 PE=4 SV=1 ---------------------------------------------------IHQGDVITEQSIANELRISRTPVKNAISKLESENFVTTLNG---RGTLVNVLSIADMRDIYNVRTVLEVlALETTIHNLSEKMVQQACESFQNALALykkdksLVSPE- ->tr|F0RTC2|F0RTC2_SPHGB Transcriptional regulator, GntR family OS=Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy) GN=SpiBuddy_2555 PE= ---------------------------------------------------IKPGEYISEKDILESAEIGRTPFREAIIMLQAEHLVEVRPR---HGTFSTRLTRTDVIEVFSMRKMLEPvAVFTYLNRIDVSKLLENDRLMErLSKNA-EEVP- ->tr|A0A0D5NJT0|A0A0D5NJT0_9BACL Uncharacterized protein OS=Paenibacillus beijingensis GN=VN24_12020 PE=4 SV=1 ------------------------------------------------------EEYTSENNLVLEMGMSRTPIREALNRLQHEGFLKILPN---RGIVFTELLTEERNELVDMRVAVETySLRQAADRIKEDDIKELSRIIELQEEAYRAGD- ->tr|A0A1C6C032|A0A1C6C032_9FIRM Uncharacterized HTH-type transcriptional regulator ydfH OS=uncultured Roseburia sp. GN=ydfH_3 PE=4 SV=1 ---------------------------------------------------YKEGTVMVERKLCDIYNMSRSPIRNALQQLTHEGLLAFIPG---KGVVVPEFTTEDILEVYDLIEILQVyAVKSCISKCTDVTLESLHLVLDKMHKSLKEED- ->tr|E1RC57|E1RC57_SEDSS Transcriptional regulator, GntR family OS=Sediminispirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) GN=Spirs_0 ---------------------------------------------------MDWGQRIDIIQIAGNYGISRSPVVKAVDRLSMEGFIDILPN---KGSFVARPSLQRINEVTEIRLMLETySLKLSMEKERKKLLQDLQENQ--KLVAEEKNK- ->tr|A0A1G2YSU5|A0A1G2YSU5_9BACT Uncharacterized protein OS=Planctomycetes bacterium GWF2_42_9 GN=A2Y12_06945 PE=4 SV=1 ---------------------------------------------------FSGNHRWSLRTLAQKFKLSMAPVNVAVRQLENEGLLTVSPQ---KGISIKQLTIPQIKEANLIREALEIqAIRLITLKNDENITNSLYEISCKITEAlkT---S- ->tr|A0A1R3XEN9|A0A1R3XEN9_9MICO DNA-binding transcriptional regulator, GntR family OS=Microbacterium sp. RU33B GN=SAMN05880545_3197 PE=4 SV=1 ---------------------------------------------------LRPGDRLVLDEIARDLGISKIPLREALSGLEAAGLVVTSPH---AGPRVAPLPFHEIRGIYLLREQVETlGMQLAVTHIDDAVVEDLRQINEEMRTGLRESD- ->tr|A0A1L9XD90|A0A1L9XD90_ACIBA GntR family transcriptional regulator OS=Acinetobacter baumannii GN=BRY75_13495 PE=4 SV=1 ---------------------------------------------------FPAGKRLIERNLCEELGVSRSVVREVIRQLEVEGLIEVLPK---KGPIVSFLNWDIACQIYDIKLLLEQnAVVACILNIGQ-EKNiEFDKLSYTINNLsyLDEID- ->tr|A0A1W9TDD7|A0A1W9TDD7_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_123 GN=B6I22_04075 PE=4 SV=1 ---------------------------------------------------LHAGQQLYEKELMREYGIGRTPLREIFHELQRDGLIEILPK---LGTKVVSMDLKMLRETVQLRKELEGlAAELATRNIAPNQLDEFRQLLMDAENIdtsdSEALI- ->tr|A0A1V4M226|A0A1V4M226_9DELT Uncharacterized protein OS=delta proteobacterium ML8_F1 GN=AVO33_09085 PE=4 SV=1 ---------------------------------------------------LVPGSRISERKYSESLNISRAPIREALKELQEQGIITSISY---KGWFVAEYDEADYREISRLRSILEDnLIECIIThghyeDKDLSRLRTLNEELKqIASNHDLDKR- ->tr|V5DZM9|V5DZM9_9GAMM Transcriptional regulator, Crp/Fnr family OS=Methyloglobulus morosus KoM1 GN=MGMO_47c00190 PE=4 SV=1 -----------------LLGVLSEKIRHLTDKVRLMALSNVYERTVKALQAMAVvegnvsviHNRPTQQELASMVGSSREMINKIMHELTKGGYVTVED-------------------------------------------------------------- ->tr|D9PUW8|D9PUW8_METTM Transcriptional regulator OS=Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 8 -----------------------------------------SSIRFRIMVSLLR-SPKTFDEIKGEVKVSLPALYSNIKLLLEEGAITRRGN-------SYSLTSEATLKTLSALKLMNSVR------------------------------- ->tr|A0A124G2Y5|A0A124G2Y5_9EURY Transcriptional regulator, ArsR family OS=Methanosaeta harundinacea GN=XE07_1857 PE=4 SV=1 -----------------------------------------SKVRNKILLCLKD-GAKSTGDLEKEMGIRNTTILHAIKDMTDSDLVTRAEK-------GYGLTNLGKLQAYLLDEMIDFVL------------------------------- ->tr|B6YUK2|B6YUK2_THEON Uncharacterized protein OS=Thermococcus onnurineus (strain NA1) GN=TON_0551 PE=4 SV=1 -----------------------------------------SNVRHKVLLSLSE-GPKILGEIHSQVGSTKSTISHVLSDLMEEMLIIQDPET-----KQYRLTNIGHLVSLQVKNIWGALE------------------------------- ->tr|A0A1V4TEN7|A0A1V4TEN7_9EURY Uncharacterized protein OS=Methanobacterium sp. PtaB.Bin024 GN=A4E25_01387 PE=4 SV=1 -----------------------------------------------------------MEELKKETGITTSTISHNLSNMEKKSITSKIGE-------KYILSPIGNIITCNLIENIKTAG------------------------------- ->tr|A0A1V4YPF5|A0A1V4YPF5_9EURY Uncharacterized protein OS=Methanomethylovorans sp. PtaU1.Bin073 GN=A4E23_00567 PE=4 SV=1 -----------------------------------------SEKRRDLLLFLLE-QPSTLTNIRKKFDVSSPEIALRIREMESANLMYKDPST-----KMYTLTTTGKIIAKSFRPFVDMVD------------------------------- ->tr|A0A1N6HDT8|A0A1N6HDT8_9SPHN Transcriptional regulator PadR-like family protein OS=Sphingorhabdus marina DSM 22363 GN=SAMN02745824_3243 PE=4 SV=1 ----------------------------------------PSKATRSALISLlNASEGKYGYEIMREAGIGPGTLYPMLARLEDQEILVSRWQEASvegrPPRHIYELTKTGRIFAQSLVDATHL--------------------------------- ->tr|A3YEL5|A3YEL5_9GAMM Transcriptional regulator OS=Marinomonas sp. MED121 GN=MED121_04758 PE=4 SV=1 ----------------------------------------INWDDVKFFLALSRSGSARSV--AEEFGMSHSTISRRIDQLEKSLgskLFNRNVS-------GYQMTEDGLALSHYAKEAEEAMKG------------------------------ ->tr|C5ANY6|C5ANY6_BURGB Transcriptional regulator, LysR family OS=Burkholderia glumae (strain BGR1) GN=bglu_4p0520 PE=4 SV=1 ----------------------------------------TEWTDLMVFVEVARGPSLTAA--GQRLGIDLSTVRRRLATLQDTLgreLFQKQGR-------SLSLSVEGERIFHIAQRMEMLASE------------------------------ ->tr|E2CF56|E2CF56_9RHOB LysR family transcriptional regulator OS=Roseibium sp. TrichSKD4 GN=TRICHSKD4_1683 PE=4 SV=1 ----------------------------------------MQTEAIRLFVLAAEKLNISAA--GKKLDMAPAVASSKLAKLEKQLgveLLHRSTR-------KVSLSLEGAEFLFYAKEMLAQEAE------------------------------ ->tr|V8QUB8|V8QUB8_9BURK LysR family transcriptional regulator OS=Advenella kashmirensis W13003 GN=W822_08980 PE=4 SV=1 ----------------------------------------NRFDSLAVFTRVVELGSFAAA--ARDLDISPAMVGNHVRALESWFgapLLLRTTR-------QQTLTDLGHEVTKRSADVLDSMLA------------------------------ ->tr|E1V3U5|E1V3U5_HALED Transcriptional regulator, LysR family OS=Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) GN= ---------------------------------------KTTLDHWNVFKTVVEQGSFHKA--AEHLERSQSTVSYAVRKLQEQLGASLI----EIRGRKAVLTPIGELLLEDGKAIVEGMLQ------------------------------ ->tr|A0A1B9P122|A0A1B9P122_ALILO LysR family transcriptional regulator OS=Aliivibrio logei GN=A6E04_09430 PE=4 SV=1 ---------------------------------------MFNLQQLETLVLCVECGSFSAA--ARKLGKAQSAVSTAIANLEIDAGIEIF----DRSTRIPTLTPHGKRLYLQSLNLLSQakDIETMIHSFSAGVEDTLTIAINELL-------- ->tr|A0A1Q9P8D5|A0A1Q9P8D5_9ARCH Putative inorganic polyphosphate/ATP-NAD kinase OS=Candidatus Heimdallarchaeota archaeon AB_125 GN=ppnK_2 PE=4 SV=1 --------------------------------------ERVPPSAKYIFKLLLTEGEMTQKELIESTGLPNRTVRNALSILKEKGVINQRPHLRDARQSIYFVN------------------------------------------------- ->tr|A0A1M5EC75|A0A1M5EC75_9ALTE DNA-binding transcriptional regulator, LysR family OS=Aestuariibacter aggregatus GN=SAMN05216361_0336 PE=4 SV=1 ----------------------------------------MNVNDLKIVLKVAEQKSIKQA--AESMDLLVATASAAVKRVETSLGVTLFQ----RSTRKLKITSAGEQALSQLAQAVALLNQ------------------------------ ->tr|A0A1V3PZ35|A0A1V3PZ35_9GAMM Uncharacterized protein OS=Rhodanobacter sp. C03 GN=B0E48_09230 PE=4 SV=1 ----------------------------------------NRLSDMQLLVDAADLNSLSAA--GRRAGLSPAAASACLQRVEAMLGARLFE----RTTRQLRLTEEGRIYIASCRVAIETMKE------------------------------ ->tr|X1UXC5|X1UXC5_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S12H4_29384 PE=4 SV=1 ------------------------------------------ATKLELLQFIYEREVVSRFDVVEKFGYTPGGADSMLAWLKREKLVT------NDRKGEWTISDDG---------------------------------------------- ->tr|R7C2I2|R7C2I2_9BURK Transcriptional regulator ArsR family OS=Sutterella sp. CAG:397 GN=BN641_00495 PE=4 SV=1 -----------------------------------------QPVRLEILEFLAQ-CPRTVETLTDLLQIDYKNVSAHLKVLLQAGLVSVRRF---GRFRQYAISsTEVLHLVVVLQQTARVTEVAA---------------------------- ->tr|I4B9X2|I4B9X2_TURPD Transcriptional regulator, ArsR family OS=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) GN=Turpa_3442 P -----------------------------------------NPIRLEMLDYLAQ-MECSVEFLAQKCNQKIGNISQHLKTMSRAGLVRSRRE---GIFIYYAQTeVAQ-TLTDALANTAVKSSPAA---------------------------- ->tr|M5S003|M5S003_9PLAN ArsR family transcriptional regulator OS=Rhodopirellula maiorica SM1 GN=RMSM_03570 PE=4 SV=1 -----------------------------------------NPHRLKMISLLAQ-GDKPIDELAKLTNQSLAAASANVKVLRNCHLIATEKR---GRSVYCSLKdPRVAELWLRFRDLGEVVVPEI---------------------------- ->tr|A0A0J6CVH7|A0A0J6CVH7_9BACI ArsR family transcriptional regulator OS=Anaerobacillus macyae GN=AB986_15020 PE=4 SV=1 -----------------------------------------SPKRLELLDLISH-SPKSVESLSQATKMSVSNTSKHLQALLDARLVTFYKE---KNFVFYKLAsPMVVSLLLSIKAVGAEQIDEV---------------------------- ->tr|A0A089UF04|A0A089UF04_9ENTR ArsR family transcriptional regulator OS=Cedecea neteri GN=LH23_02400 PE=4 SV=1 -----------------------------------------NGARIEILEHLAG-GELSVEMLSGLTGMSTASTSQHLQNLRKGNFVASRRD---GKHIIYRLAdGPVRSVIASLRCFAEYNNEAI---------------------------- ->tr|L0HAS1|L0HAS1_METFS Uncharacterized protein OS=Methanoregula formicica (strain DSM 22288 / NBRC 105244 / SMSP) GN=Metfor_0017 PE=4 SV=1 -----------------------------------------TSASLPICEFLSSFPDASRQDIAQRLKTTGSTVSWHMRRLCEARLITSARE---GRTVRYSLTPVAVKVIGDLR-------------------------------------- ->tr|A0A0E3NUT2|A0A0E3NUT2_9EURY Uncharacterized protein OS=Methanosarcina sp. MTP4 GN=MSMTP_0786 PE=4 SV=1 ------------------------------------PEAYLPEDLKEVLELIRASGNrITQLELRKKSRYSESKVSLMLSDLEERGMIEKFKK---GRGNIIRIQDEHV--------------------------------------------- ->tr|A0A1A8Z5J1|A0A1A8Z5J1_9ACTN Transcriptional regulator, BadM/Rrf2 family OS=Micromonospora narathiwatensis GN=GA0070621_0594 PE=4 SV=1 ---------------------------------------------LRIAMLTAAsPARTTVDELATRLALPRSHVAKVVQRLQRLGVLVTLR----GRSGGVAFAERAGEL------------------------------------------- ->tr|V2VK69|V2VK69_9GAMM Uncharacterized protein OS=Acinetobacter indicus CIP 110367 GN=P253_02037 PE=4 SV=1 ---------------------------------------------LRILLYISPprDLPYTIAEIAQDLHVSQNHLVKIVHFMGKQEWLITTR----GKGGGLRLNPDARDL------------------------------------------- ->tr|B8F6L8|B8F6L8_HAEPS Transcriptional regulator OS=Haemophilus parasuis serovar 5 (strain SH0165) GN=HAPS_1390 PE=4 SV=1 ---------------------------------------------FRVLMYLAHhqDELRTIPQLAESLQVSQNHLVKVVHFMAKQGWLITAR----GKGGGIRISSLILSM------------------------------------------- ->tr|A0A0P7C006|A0A0P7C006_9ACTN Uncharacterized protein OS=Frankia sp. R43 GN=ACG83_24380 PE=4 SV=1 -----------------------------------------LRKQRVLELLAAESPL-SRAEIATRLSLTNRQATYALTRLTSDGLIDRTTKTHSDPHATYRLAKPP---------------------------------------------- ->tr|L8DF86|L8DF86_9NOCA Putative transcriptional regulator OS=Rhodococcus sp. AW25M09 GN=RHODMAR_2241 PE=4 SV=1 --------------------------------------------RESVEEAIAQMGEAGALELAERAGISRVAVVKQLNALIERGSVRADGV-PRSPKRRYVWLGHG---------------------------------------------- ->tr|C8VVL1|C8VVL1_DESAS Putative transcriptional regulator OS=Desulfotomaculum acetoxidans (strain ATCC 49208 / DSM 771 / VKM B-1644) GN=Dtox_1459 PE=4 ------------------------------------------ADSKKIWKYVRDNQPVARKEIiKALKGIFTENqIDYRLEKLVENNLIVATNLKEKASNRKYIIK------------------------------------------------- ->tr|A0A0G0MRX2|A0A0G0MRX2_9BACT Uncharacterized protein OS=Candidatus Uhrbacteria bacterium GW2011_GWF2_39_13 GN=UT30_C0037G0002 PE=4 SV=1 -------------------------------------------EEEKVLEYIRKYKSITNAQCREMLGNDDLQkASRILKRMHKNGKLKQGGER---RWAKYTLP------------------------------------------------- ->tr|A0A087CGP5|A0A087CGP5_9BIFI Transcriptional regulator OS=Bifidobacterium psychraerophilum GN=BPSY_1296 PE=4 SV=1 -----------------------------------------KNFAQRIVTLLEQRPSASVRDIMVDLHLSPIAVATGLRALLNKGLVESVTA-QPHPQKQYRLLNPH---------------------------------------------- ->tr|A0A087DTN7|A0A087DTN7_9BIFI Transcriptional regulator OS=Bifidobacterium subtile GN=BISU_2089 PE=4 SV=1 -----------------------------------------DNMRSAILAYLAERQNASTSELANAAGVSTKTIRDYISRLMEEGLAEGIGS-KYSPKRRYRLIASH---------------------------------------------- ->tr|A0A086ZVG7|A0A086ZVG7_9BIFI Transcriptional regulator OS=Bifidobacterium biavatii DSM 23969 GN=BBIA_1740 PE=4 SV=1 -----------------------------------------GDISKAITTVLERHSAMSAKEIMRELQLTPLAATAGLRELLREGRVIPVRF-QEDPAQRYRLNIGH---------------------------------------------- ->tr|F7UZ11|F7UZ11_EEGSY Uncharacterized protein OS=Eggerthella sp. (strain YY7918) GN=EGYY_05410 PE=4 SV=1 -----------------------------------------ESIEYAIIQIAEAKESVSMKELMDALKRSRPTVRKRVANLVARGVLVPTQA-KNSPQQRYRLSARF---------------------------------------------- ->tr|A0A1H2CJJ3|A0A1H2CJJ3_9ACTN ATP-dependent DNA helicase RecG OS=Actinoplanes derwentensis GN=SAMN04489716_5995 PE=4 SV=1 ------------------------------------------SNERRIWRALDDGPL-PRADIEVATGLSVDIVKRGLQSLRRKGFVTLIGQQR-SRDARWAK-------------------------------------------------- ->tr|A0A1G1LXY8|A0A1G1LXY8_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium GWA2_53_43 GN=A2Y05_00695 PE=4 SV=1 -----------------------------------------RDRRQEILAIIKGRGECGRREIKEIVPLSSAGIIYWLRKLVQEGKIEPTTDSLKDPGVKYRIKLNK---------------------------------------------- ->tr|A0A1F1J516|A0A1F1J516_9MICC Uncharacterized protein OS=Rothia sp. HMSC067H10 GN=HMPREF2756_06790 PE=4 SV=1 -----------------------------------------QGRNELILSLLRGHELSIleLLEGleKQGVRVARPTLTKDLNELVSRGSVEATAP-PRSKNRTYRIPR------------------------------------------------ ->tr|A0A1J4TL27|A0A1J4TL27_9BACT Uncharacterized protein OS=Elusimicrobia bacterium CG1_02_63_36 GN=AUJ52_01135 PE=4 SV=1 --------------------------------------------PKMVYSIIQNDGPIRALTIAEECGISKAYVKLIVRDLLKSKLIETMEKNPRSPKQAYRVKSFH---------------------------------------------- ->tr|A0A021X7F5|A0A021X7F5_9RHIZ Transcriptional regulator, GntR family OS=Shinella sp. DD12 GN=SHLA_73c000220 PE=4 SV=1 -----------------------------------------------MLGVLPAGAALTELDLAAHFACSQGTVREALLQLQEEGLVRRQGH---RGTQVSECTEAEAVEMFRVRLQVECsGIVRTLQAPSRTLVGDLKALFAEMLDAAKVGDE ->tr|A0A1S2DSW1|A0A1S2DSW1_AGRVI GntR family transcriptional regulator OS=Agrobacterium vitis GN=BBK77_10670 PE=4 SV=1 -----------------------------------------------MLGLLPAGAALTELELAAHFSCSQGTVREALLQLQEEGLVLRNGH---RGTQVSQCTEAEAVEMFRVRQQIECnGIIRVMGARSASLVPDLRGLLADMLEAAQAGDE ->tr|A0A1E2S2S1|A0A1E2S2S1_9RHIZ Uncharacterized protein OS=Methyloligella halotolerans GN=A7A08_00456 PE=4 SV=1 -----------------------------YRRFIQRAGLELRPQELWLLNRLSVIVGARSEHLAEALRHPQERLVAPLASLQRQGLVSGGDD-------SLTVTEEGRAVLIKIERARTDSLTELFSEWAPGGHYEIQRILDKFTKTLSK--- ->tr|A0A1Q8E5W1|A0A1Q8E5W1_9STRE PadR family transcriptional regulator OS=Streptococcus cuniculi GN=BU202_08905 PE=4 SV=1 -------------------------RRNGMEEKIRRVYLPMTETAFYILFALQEERhGYDITQKTkeltgGQVVISPGTMYGTLSKMEKDGLIAFIRE--EEKRKLYLITELGREILEIEKARIERLYRNSRGEKYETA-------------------- ->tr|A0A1V4HN17|A0A1V4HN17_9BACL PadR family transcriptional regulator OS=Paenibacillus ferrarius GN=BC351_21990 PE=4 SV=1 ----------------------------MNKDKIQRNYLPMSETAYYILLSLIKTRhGYGIMQHVeeitkGRIKLGPGTLYGSLSKMEKDTLIHVIAE--EDRRKVYQITALGRNILTQEIARLSELFHNSKSVEDDQH-------------------- ->tr|A0A1T8WCV3|A0A1T8WCV3_9MYCO Uncharacterized protein conserved in archaea OS=Mycobacterium abscessus subsp. massiliense GN=SAMEA2275645_05749 PE=4 SV=1 --------------------------------------------------------GLSNKDLSVGLGLTPSQVSRDIDDLVASGLVIKLENGNYAYgIKTLQIAERFRKQQERLNARLQELENRIY--------------------------- ->tr|A0A0H6ZBM4|A0A0H6ZBM4_VIBCL IclR family transcriptional regulator OS=Vibrio cholerae GN=BTY66_06300 PE=4 SV=1 -----------------------------------------TTIALVILETLFEYGikGATFRDIGFKTQIPRATLHRYLTALVDAGWVEACGS---KQNMVWKPSNHFIKLAFTYRNAVRAEVDRIgaeFRELTGEDL------------------- ->tr|A0A0B1ZK18|A0A0B1ZK18_9SPHN Uncharacterized protein OS=Novosphingobium malaysiense GN=LK12_11595 PE=4 SV=1 ---------------------------------------------LRTIDAISEQQPIGVSALAQLLGDDRSAMQRTVLTLSDAGWIRLAPGtpkkwELTPHLFSIANLArSGDALRRKARTVLNRLCEE----------------------------- ->tr|A0A0D8HQ52|A0A0D8HQ52_9NOCA Acetate operon repressor OS=Rhodococcus sp. AD45 GN=iclR_5 PE=4 SV=1 ---------------------------------------------CRLFEAIARMQPVGVSDLARDIGIDKSAAHRLAITLHSARWLERTEDgrwSISPAILPTFRESAATTLVTGTRPLLEAARDQ----------------------------- ->tr|A0A0B1ZUA1|A0A0B1ZUA1_9SPHN Uncharacterized protein OS=Novosphingobium malaysiense GN=LK12_06120 PE=4 SV=1 ---------------------------------------------LSVFESIAHAQPIGVSALARLLEADKSAVQRDLMTLADAGWIRPAPGlagqwELSPHVLTLARPPhSNESLRLRAGPILERLRTE----------------------------- ->tr|A0A1Q9QZB1|A0A1Q9QZB1_9PSED Uncharacterized protein OS=Pseudomonas sp. GM4FR GN=PSEMO_48790 PE=4 SV=1 ---------------------------------------------FRLLDELTAaRRPLGVTELAQLLQTAKPRTYRHLASMRQLGILEQDPAsekyMLGARLVAYGEAAgEQFDLRAIADPYLTRIRDA----------------------------- ->tr|A0A136Q514|A0A136Q514_9FIRM ROK family protein OS=Christensenella minuta GN=HMPREF3293_01461 PE=4 SV=1 -----------------------------------------------ILRLLKKNNVCSRAKLAKQSGLKQATITNIINDFLNWGLVNETgiiSGEKGRSSIGIQINHQNYYVI------------------------------------------ ->tr|A0A0M2NCK2|A0A0M2NCK2_9FIRM Mlc, transcriptional repressor of MalT and manXYZ operon OS=Catabacter hongkongensis GN=CHK_2297 PE=4 SV=1 -----------------------------------------------ILKLLQRNRLCSRARLAKQSGLKQATITNIINDFISWDIVRETgsiEGKKGRRSIGLTINDQKFFVV------------------------------------------ ->tr|A0A1Y4EPK4|A0A1Y4EPK4_9FIRM Uncharacterized protein OS=Anaeromassilibacillus sp. An250 GN=B5F54_16400 PE=4 SV=1 -----------------------------------------------IIDLLRQQGVCSRATLAHLSGLKQATITNIIAECITSGLVMETglmSGSKGRRSIGITLNEEHCHVI------------------------------------------ ->tr|A0A0A1Y9S2|A0A0A1Y9S2_9SPHN Uncharacterized protein OS=Sphingomonas sp. BHC-A GN=AI27_06435 PE=4 SV=1 ----------------------------------------MTERETMLVGIVRECteaalPVPSIDDIAERLGVaNGGTVPELFRRLHDMGVIINKPF---QRGRQVCLVETGK--------------------------------------------- ->tr|A0A239KC79|A0A239KC79_9SPHN Uncharacterized protein OS=Sphingomonas laterariae GN=SAMN06295912_1505 PE=4 SV=1 ---------------------------------------DPRLAEALVFTAVAEAadvgaPCPSNQDLADIIDGSVSSPPYILTRLQRQGLIAIERY---QKERRITIVETGK--------------------------------------------- ->tr|A0A0F7D195|A0A0F7D195_SERFO Uncharacterized protein OS=Serratia fonticola GN=WN53_05345 PE=4 SV=1 -----------------------------------LSIRSASLRDFEIIKAIIEKGSATQA--AESLGISQPAVSKAVASIEEKlgkTLFTREKG-------RLNPTKDALFFYEEIVNIFNSLER------------------------------ ->tr|A0A1Y6IXZ6|A0A1Y6IXZ6_9VIBR HTH-type transcriptional regulator CynR OS=Vibrio mangrovi GN=cynR_3 PE=4 SV=1 -----------------------------------LSGSWATLRELEIIKTIIEVKTVTSA--AEILGVSQPAISRALTQIETKsgvKFFNRKSG-------KLIPTSNAIALYDEILVIYNSFSK------------------------------ ->tr|A0A150JD15|A0A150JD15_9EURY Bacterial regulatory protein, arsR family OS=Arc I group archaeon ADurb1013_Bin02101 GN=AN188_00358 PE=4 SV=1 ---------------------------------------------ALILKYVISNP-SNANRISLATGIEYKTVQHHLNILEKNGLLSAIGD---KYGKTYFPSELLDRNINNFNEICKNM-------------------------------- ->tr|A0A150J328|A0A150J328_9EURY Bacterial regulatory protein, arsR family OS=Arc I group archaeon U1lsi0528_Bin055 GN=AMQ22_01305 PE=4 SV=1 ---------------------------------------------ALILKYVISSP-SNANRISIATGIEYKTVQHHLSILEKNGLLSSVGD---KYGKTYFPSELLDKNISSFNEICKNM-------------------------------- ->tr|A0A089ZUV5|A0A089ZUV5_METFO ArsR family transcriptional regulator OS=Methanobacterium formicicum GN=BRM9_0521 PE=4 SV=1 ---------------------------------------------ARIIDELNSRP-YNANQLAKCLKLDYKTVKHHLNVLIKNNIVTACGEG--HYGTVYMLSATMEKNYDSFKKIWKES-------------------------------- ->tr|A0A1J6XG86|A0A1J6XG86_9GAMM LysR family transcriptional regulator OS=Acinetobacter sp. AR2-3 GN=BFN00_13890 PE=4 SV=1 --------------------------------------------------FVKVMETGSISLAADQLFITQPAVTKRIHSLEEYFGVKLF----ESAGRGVQATHAAHSLLPKVKNWLNELGD------------------------------ ->tr|F4FEE5|F4FEE5_VERMA ArsR family transcriptional regulator OS=Verrucosispora maris (strain AB-18-032) GN=VAB18032_25565 PE=4 SV=1 ----------------------------------------LGGTRAAVLRQlgEPG--RHTTTTVSRLVGISVSSASEHTAALRGAGLVDSERV---GGAKVHRLTPLGIHLLA----------------------------------------- ->tr|J2I6V4|J2I6V4_9RHIZ Transcriptional regulator OS=Rhizobium sp. CF122 GN=PMI09_04445 PE=4 SV=1 -MDlakfEGKYIASRTQSALYLGAKFASLFRLEVQMGATARRVALDDFDRQILAILQKDNMTPQRTIGEAVNLSAPAVQRRMKRMTEAGVIQANVAIVDPAALGHPIT------------------------------------------------- ->tr|X4ZQH2|X4ZQH2_9BACL GntR family transcriptional regulator OS=Paenibacillus sabinae T27 GN=PSAB_19185 PE=4 SV=1 --------------------------------------------ELIIKREFPPEHKLSIPELSTQLGVSRTPIRDALGRLEKDGLIKTVPK---VGTFVVGVSAENVLDIMETRLMIELWVVEKLAAGKAEASPNIIANMEKIHE------- ->tr|A0A078KV78|A0A078KV78_9FIRM Transcriptional regulator, GntR family protein OS=[Clostridium] cellulosi GN=CCDG5_1993 PE=4 SV=1 --------------------------------------------DEITFLIIPPNQRISEIEVAKRFNVSRTPIRDVFKRLEVEGFLKIIPQ---KGTYVTRIDMSDLADMMYLREKIELAVVEDLCGKlSQDQIIRLQFQIAQQKK------- ->tr|A0A0F2SDK9|A0A0F2SDK9_9FIRM Uncharacterized protein OS=Peptococcaceae bacterium BRH_c23 GN=VR66_15320 PE=4 SV=1 ----------------------------------------LSNAELIILSLVNEKPsyayeiekQIETKSMRLWVRIGIASIYQVLTRLNGKGYLEFKIEREGKApeRKRYCITESGQEILKS---------------------------------------- ->tr|A0A0P0N4C5|A0A0P0N4C5_9CREN Uncharacterized protein OS=Pyrodictium delaneyi GN=Pyrde_1703 PE=4 SV=1 ----------------------------------------------ILEILSKSKNGLTFDEIYNALLEhdsnvKKETIRETLAGLVRRGIIIREPDYERKKMV------------------------------------------------------ ->tr|A0A1F7Q4V0|A0A1F7Q4V0_9BACT Uncharacterized protein OS=Candidatus Saccharibacteria bacterium RIFCSPHIGHO2_01_FULL_46_30 GN=A2791_01860 PE=4 SV=1 ------------------------------------KGQKLTGQQQRVLKLLFKFRFVSAGLLADVMGIHRVSVYEVLEQLVSKKLVAKVYEPKfriDRKPAYYYLNKSGVTAVRKLMDVKESVVHALYKN------------------------- ->tr|A0A1J5I1M5|A0A1J5I1M5_9BACT Uncharacterized protein OS=Candidatus Saccharibacteria bacterium CG2_30_41_52 GN=AUK57_00705 PE=4 SV=1 ------------------------------------RYNKLNAKQLHILTLIYKFRFISIPLLTEYQNLKSQTtLLRNLKILEEQGYIGRRFDLTfkiDRKPAYYYLAAKGIAVLKDDPRFDTGVLHSYYKN------------------------- ->tr|A0A0V8RUC4|A0A0V8RUC4_PYROC Uncharacterized protein OS=Pyrodictium occultum GN=CF15_01805 PE=4 SV=1 -------------------------------------GGGLTPSQAAVLLAVYR-GVDRVEELARALRLPRETVEDIVGELEAMGMLEEYRSGLIFKRRRLRLTRRGLDAVPEAMRLMEHAAQAA---------------------------- ->tr|A0A0F9V682|A0A0F9V682_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0180300 PE=4 SV=1 --------------------------------------------------FCSAAEAPSFREAASRLGTSPQTVTRAVQELEELlgePLFHRNTR-------QIHITGFGESMALQAREALATVDG------------------------------ ->tr|A0A0F9FD14|A0A0F9FD14_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1967630 PE=4 SV=1 ----------------------------------------LSPIQYNLIRTLESVGPLTRKDLVKQLRTPRTTIYDNLAKLQKRKLLEKFSRNIGKRGRPLVI-------------------------------------------------- ->tr|A0A0B1TZ78|A0A0B1TZ78_9DELT Zinc uptake regulation protein ZUR OS=Desulfovibrio sp. TomC GN=NY78_1664 PE=3 SV=1 -----------------------------GKTMLTRAGIDPTPLRLAVAEVLAGEGrALPAGDILTLVrrqhQANKVTLYRILDLFVEKGLARRHSS--GDRALRYCLEPG----------------------------------------------- ->tr|A0A1F1JWU9|A0A1F1JWU9_9MICO Uncharacterized protein OS=Kytococcus sp. HMSC28H12 GN=HMPREF3099_09235 PE=4 SV=1 -----------------------------AEDALRAQGVRVTKPRREVLALLAAVAdLPTADEMLERLdpaaGATRATLYRTLQVGVEVGVVCHVHT--GHTPTRYHLSAP----------------------------------------------- ->tr|A0A1G1N809|A0A1G1N809_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_02_FULL_48_11 GN=A3D10_08780 PE=3 SV=1 -----------------------------VVELLARGQVASTVHRVGVLKVISRSPkAIAPRSLLQEIrkttPIDKVTLYRILDLFVAKKILRRMTG--QKGTMCYEVMCE----------------------------------------------- ->tr|A0A1I0BQX4|A0A1I0BQX4_NITER Fur family transcriptional regulator, ferric uptake regulator OS=Nitrosomonas europaea GN=SAMN05216309_11826 PE=3 SV=1 -----------------------------AEQLIQNAGKRSTPVRSAVLGVLLNAEdVLSHSEVLEHLqqlgAFDRVTVYRALDWLVTQGLVHKVAG--AGRAWRFQVTRS----------------------------------------------- ->tr|E7NWK1|E7NWK1_TREPH Transcriptional regulator, GntR family OS=Treponema phagedenis F0421 GN=HMPREF9554_02466 PE=4 SV=1 ---------------------------------------------------IPGGYNLKQEELAKALGVSRIPIRETLMTLESLGLVYRKA------TRHFFTVDFSAEEIIRIFQVAFNFELESIRNFNNEE-------------------- ->tr|A0A1N6G374|A0A1N6G374_9RHOB LysR family transcriptional regulator, regulator for metE and metH OS=Rhodovulum sp. ES.010 GN=SAMN05444722_0130 PE=4 SV=1 ----------------------------------------LELRHLRTIKAIHDAGGLARA--AERLNITQSALSHQVKGLEEQVGMELFV----RRTKPLRLSSAGLKLLRAAERVLPEIAALQAEFdgLKSGRSGRL---------------- ->tr|A0A225LZR3|A0A225LZR3_9BURK LysR family transcriptional regulator OS=Candidimonas nitroreducens GN=CEY11_22170 PE=4 SV=1 ----------------------------------------LEIRHLETLSAIRDTGSLQEA--AEHLHVTQSALSHQLRDLEVRLKTPLLN----RRTRPARLSTAGLRLVALADEILPRVKATERELqrLAAGRTGRL---------------- ->tr|Q2Y4V6|Q2Y4V6_9ARCH Putative uncharacterized protein C5_0050 OS=uncultured archaeon GN=C5_0050 PE=4 SV=1 ---------------------------------------------LDILKVTSeGEGRAKKTRIMQYAYLDWRNFQRHFGFLQENRFISDHNDPKEG--TSYYLTEKGIDLMGRLNAV------------------------------------ ->tr|A0A133VFN4|A0A133VFN4_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382A20 GN=AKJ51_05210 PE=4 SV=1 ---------------------------------------------SDILETVKNENDCKKTTIIRLANLDWDMASKYLNDLDKDGFLESFEDESKGN-EVFELSKKGKLLLKSLKKI------------------------------------ ->tr|A0A1F8P7I2|A0A1F8P7I2_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_50_9 GN=A2144_05980 PE=4 SV=1 ---------------------------------------------ADMLRVG--ESGAGKTEIMYSANMSFNQIQKYLDYLVNQGFIAKVSLDNTM--VAYQVTESGLKLLKAIDTL------------------------------------ ->tr|A0A0R2DFZ1|A0A0R2DFZ1_9LACO Transcriptional regulator (Transcriptional regulator, lysr family) OS=Lactobacillus rennini DSM 20253 GN=FC24_GL000302 PE=4 SV= ----------------------------------------MNLNQLRYFRVIVDEKQYTKA--ASKLFISQPSLSNSMKAFEEDLGGKLFN----KRGHQIELTKYGQLIYKTVCNTLDTLDQ------------------------------ ->tr|A0A1A9CK19|A0A1A9CK19_9ACTN Transcriptional regulator, ArsR family OS=Streptomyces sp. Ncost-T6T-1 GN=YW5DRAFT_03881 PE=4 SV=1 -----------------------------------------DPTRLQILRLIERSParEACVCDLTDCLGLRQPTVSHHLKVMTDAGILTRERR---GTWAWFSVDPEGLRRIRDILE------------------------------------- ->tr|A0A167FEY3|A0A167FEY3_9GAMM Uncharacterized protein OS=Pseudoalteromonas luteoviolacea H33 GN=N476_11225 PE=4 SV=1 ---------------------------------------KLNWDDFKVAHTVAKAGSLAKA--ATILKCNHTTVLRHINRLEDALNVTLFI----RHQRGYQLTDAGQIMSETLEDLNTQFIA------------------------------ ->tr|A0A1M5KDP9|A0A1M5KDP9_9RHOB DNA-binding transcriptional regulator, LysR family OS=Thalassobius maritimus GN=SAMN04488044_0933 PE=4 SV=1 ----------------------------------------FDWNDLRHLLAVHRTGSYSEA--GRRLGVSETTVSRRIAAIEAAlrvKLIQKRGSA------GYEMTDIGHLVLEHAEAIEQQSGK------------------------------ ->tr|A0A0F9HHQ0|A0A0F9HHQ0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_2062450 PE=4 SV=1 ---------------------------------------------------IKYGDNLKIQKLAEKLCVSTMPVREALKRLQYERIVDIKPR---SCCSLRIPSKSEVIEIYELREVLELhAITKFRQNFDKSRLERLHEITESMRG------- ->tr|A0A149ZNP4|A0A149ZNP4_9NOCA Uncharacterized protein OS=Rhodococcus sp. LB1 GN=AZG88_17030 PE=4 SV=1 ----------------------------------------------TFIDALFREGPSSRAQIAKSTGISKPTISESAQRLLSTGLIVEVGQTATGMRGRS---------------------------------------------------- ->tr|A0A0X8JHH0|A0A0X8JHH0_9DELT Heavy metal resistance protein CzcA OS=Desulfovibrio fairfieldensis GN=AXF13_01455 PE=4 SV=1 --EDAAFIREHPVQIANLLRSMGIKMLIHYTFLADMGTGRHEIHLCRFILSLARKnnsqsafpCHMTQQEVADLLGIHRATLARALQRLKQHGVISS---------------------------------------------------------------- ->tr|A0A1T4VPP6|A0A1T4VPP6_9DELT cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases OS=Desulfovibrio bizertensis DSM 18034 GN= --LSEEFYRRNPEKAINLITTLAVKEAISYAYTTDVACADAMGRVCQSLLALVNEnqnqdvfsPDVTQSEIASMMGLHQTTVARAIKELRAKKIIGK---------------------------------------------------------------- ->tr|S2KKB6|S2KKB6_9GAMM Uncharacterized protein OS=Halomonas anticariensis FP35 = DSM 16096 GN=L861_09675 PE=4 SV=1 -------------------------------------GTDLTSHQMELLSRVLQHGGVLASPFGHAGEDSlLSRVLEDIGELESRGLITVKRFQDSQDPQQIELTAMGYAAL------------------------------------------ ->tr|K2QDH4|K2QDH4_9LACT Negative transcriptional regulator-copper transport operon OS=Lactococcus garvieae DCC43 GN=C426_1047 PE=4 SV=1 ----------------------------------NETEFNISNAELIVMRVIWSLGEARvdeiSCQISPDLDWSLATVKTLLGRLVKKGMLSTEKE---GRKFVYHPL------------------------------------------------- ->tr|U1HCQ4|U1HCQ4_9BRAD O-acetylhomoserine (Thiol)-lyase OS=Bradyrhizobium sp. DFCI-1 GN=C207_04181 PE=4 SV=1 ---------------------------------------------WSLLIIRDASLGRRrFGEFQASLGLAKNILATRLRTLVERDILKTVPASDGSAYQEYVLTPKGHGIFPILVALRQWTEEFDEHP------------------------- ->tr|A0A0D7Q9C9|A0A0D7Q9C9_9BRAD Transcriptional regulator OS=Bradyrhizobium sp. LTSPM299 GN=UP10_20280 PE=4 SV=1 ---------------------------------------------WSLLIVRDAFDGLRrFGDFQKNLGIAKGMLTTRLSKLLELDVLELVAASDGSAYQEYALTKKGRELFPIVVALRQWGEAHLYAR------------------------- ->tr|A0A193GBZ0|A0A193GBZ0_9BORD Transcriptional regulator OS=Bordetella flabilis GN=BAU07_07525 PE=4 SV=1 ---------------------------------------------WTLLILRDAFDGLKrFNAIQKSLGIPRNILTARLRLLVDRDILGVAPASDGSVYQEYVLTDKGRDLIPVISALRQWGEQHALAP------------------------- ->tr|U4T7R5|U4T7R5_9GAMM Transcriptional regulator, IclR family OS=Psychrobacter aquaticus CMS 56 GN=M917_0844 PE=4 SV=1 ---------------------------------------------LKVIKAMRSATfsGISVTELAKTIDTSAANICRDLDDLVSEGMAEKRDDG------RYQLSVAMLQIATAYQTDYNRMSSRL---------------------------- ->tr|L8DPL0|L8DPL0_9NOCA Transcriptional regulator, PadR family OS=Rhodococcus sp. AW25M09 GN=RHODMAR_3209 PE=4 SV=1 --------------------------------------------RAAILLLLEDRPMHGyelIQQIAEKSNGtwkpSPGSIYPALSQLEDEGLVLIDKV---AGRKTAKLTEEGRTYVDDHRADLGSPWDDVADSVGVDARDLRALIGQLM--------- ->tr|A0A164LAT7|A0A164LAT7_9NOCA PadR family transcriptional regulator OS=Rhodococcus sp. EPR-147 GN=A2J02_03105 PE=4 SV=1 --------------------------------------------RAAILLLLEERPMHGyelIQQIAEKSNGtwkpSPGSIYPALSQLEDEGLVLIDKV---AGRKTAALTDEGRTHIEAHRADLGSPWDDVAESVGVDARDLRALIGQLM--------- ->tr|A0A1J5K2V2|A0A1J5K2V2_9PROT Uncharacterized protein OS=Bacteriovorax sp. MedPE-SWde GN=BM556_16110 PE=4 SV=1 -------------------------------------------------SFVELSKTLNFSKAAKNLSMAQPGLSRQIRQLEESLQTSLFL----RDNKRVTLTQEGEYLRDHISPLLLGINDAV---------------------------- ->tr|S3V4F4|S3V4F4_9LEPT DNA-binding helix-turn-helix protein OS=Leptospira wolffii serovar Khorat str. Khorat-H2 GN=LEP1GSC061_1571 PE=4 SV=1 -----------------------------------------DPTRRSILERLSL-GPATVGELAEPFSMALPSFMQHLGVLEESSLVSSVKS---GRVRTYSLTHSTLDLGEEWFVKQRTVWER----------------------------- ->tr|A0A127F0D3|A0A127F0D3_9RHIZ ArsR family transcriptional regulator OS=Rhodoplanes sp. Z2-YC6860 GN=RHPLAN_46740 PE=4 SV=1 -----------------------------------------DPTRRAIVSRLCD-GPKSVSELSEPFELALPSLLKHLRALEQSGLISSEKI---GRVRTCRIEPRALHATEAWIRQHISAWEK----------------------------- ->tr|X8K4T5|X8K4T5_9FIRM FCD domain protein OS=Eubacterium sulci ATCC 35585 GN=HMPREF9092_1507 PE=4 SV=1 --------------------------------------------QSAILRGEFEYGeLVSEKKLAEKLGVSRTPVREAMTRLSQDRLIKDTV----NGSIILGIQPKDLRDLIIIKQRIEPlIAVSLTENMTEKELNRLKDIVDQ---------- ->tr|A0A220U3V1|A0A220U3V1_9BACI Uncharacterized protein OS=Virgibacillus sp. LM2416 GN=CFK37_10250 PE=4 SV=1 --------------------------------------------QNHLLENEFSPGeRLTESGLANMLGVSRGPIREAIRMLIHDGLLVQKG----VHIYVFDPTFDDVVDVYLCKERLEPlGAKLSAQNMSQADNEALMDIINR---------- ->tr|R7WIP2|R7WIP2_9NOCA GntR family transcriptional regulator OS=Rhodococcus rhodnii LMG 5362 GN=Rrhod_3564 PE=4 SV=1 ---------------------------------------------------------LSQVRLATELQVSRTPLREALRRLEAENLVVNQA----NRGVVVAPVALGDVEDSYAIRTLVEpsLLTATLETISQDDITAMSTALMRMKEA------ ->tr|R7WIQ2|R7WIQ2_9NOCA GntR family transcriptional regulator OS=Rhodococcus rhodnii LMG 5362 GN=Rrhod_3562 PE=4 SV=1 ---------------------------------------------------------MSQEQLAAEFEVSRTPLREALQRLEADGLLVAEA----NRGMHVAPIVNSETEESYALRLLVEppTVAAVIDHLTDADFAAMAKALEQMRRH------ ->tr|A0A0E3S1Y1|A0A0E3S1Y1_9EURY ATP-dependent DNA helicase OS=Methanosarcina lacustris Z-7289 GN=MSLAZ_0845 PE=4 SV=1 ---------------------------------------KLTETQKLMLRLVKESPYISIKEMSEIIGIRTSSIDKNIQTLKKKGLIKRVGPARGGHWEAIE--------------------------------------------------- ->tr|A0A0D2VZ17|A0A0D2VZ17_9PROT GntR family transcriptional regulator OS=Skermanella aerolata KACC 11604 GN=N826_11615 PE=4 SV=1 ----------------------------------------------------------PERDLEKQFGVSRNTLRKSLKLLQDKGRIVRHV----GRGSFVAPARQDLPqsrALDSFVPVSADSLVLRIHGASPAEIMEVRLVVE----------- ->tr|E8REJ2|E8REJ2_DESPD GntR domain protein OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1920 PE=4 SV=1 ----------------------------------------------------------PERKLAESLGVSRGSLRQAFHILAERGIIESRQ----GDGTYLLAPLGGGC----SA-EA-ILDAIGEQSGFVHDIIEFRQMIE----------- ->tr|A0A1R0YB10|A0A1R0YB10_9BACL Uncharacterized protein OS=Paenibacillus borealis GN=BSK56_22865 PE=4 SV=1 ----------------------------------------------------------TLQQLAADFSVSVTTVREALRILESQGNVSIEH----GRGMYVRNDPLLLD----DP-AV-ALEEL--ENISIVDLLEARLLIE----------- ->tr|A0A1Q9PBY0|A0A1Q9PBY0_9ARCH HTH-type transcriptional regulator OS=Candidatus Heimdallarchaeota archaeon AB_125 GN=HeimAB125_15210 PE=4 SV=1 ----------------------------------------------KILTLLGNMK-LTADELTKELGISRPAVEKHLKQMLEIGLIERKADTYPTLKYIYTIPSPGLELLSNVRDSIDTFISSLREEYT----------------------- ->tr|W6WCP5|W6WCP5_9BURK Transcriptional regulator, LysR family OS=Burkholderia sp. BT03 GN=PMI06_008851 PE=4 SV=1 ---------------------------------------AIELRQLRYFSILARELHFGRA--ADLASITQSALSQQVAKLEELVGAQLL----NRDRRGVTLTASGEALRNSADAIFAQVERGL---------------------------- ->tr|A0A0Q0XIM7|A0A0Q0XIM7_9FLAO ArsR family transcriptional regulator OS=Flagellimonas sp. DK169 GN=AAY42_13630 PE=4 SV=1 ------------------------------------------------------NDGVCVGYIQDKTGLSQSTISTYLNSMQNANLVIPTRH---GKWTYYKRNEEVIEAYVESLK------------------------------------- ->tr|A0A163Y443|A0A163Y443_9FLAO ArsR family transcriptional regulator OS=Myroides marinus GN=AV926_00925 PE=4 SV=1 ------------------------------------------------------DYGVCMSVIQKKAGLSQSTTSAYLTNMVNIGLLTSVRN---GQWTYYKRNEDKIAELAHYIQ------------------------------------- ->tr|A0A1Y2PBJ5|A0A1Y2PBJ5_9FLAO ArsR family transcriptional regulator OS=Tenacibaculum holothuriorum GN=WH52_10400 PE=4 SV=1 ------------------------------------------------------DFGVCGTFIQKKTEMSQSTISTYLNNMEKCELLISTRK---GKWTYFKRNEKTIEDYIEYLK------------------------------------- ->tr|A0A133VNG9|A0A133VNG9_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382N08 GN=AKJ56_02010 PE=4 SV=1 ------------------------------------EKLGFTERQYQILNHVQDNGETLSKEVAKKLDIDIHNASMRLKDYYENGWLSRERGA--YGRFKYTITEQGENRIDWLEE------------------------------------- ->tr|M1E6M1|M1E6M1_9FIRM Segregation and condensation protein B OS=Thermodesulfobium narugense DSM 14796 GN=Thena_1242 PE=3 SV=1 ----------------------------------SEKDnKRLSKSMLEVLAIIAYNQPISASGVSKIRG---LRSEKQVMKLFENGFIKILSF---NNApikqPLFGVSTK----------------------------------------------- ->tr|A0A0Q4BC52|A0A0Q4BC52_9EURY Uncharacterized protein OS=Methanomassiliicoccales archaeon RumEn M2 GN=AOA81_01875 PE=4 SV=1 ----------------------------------KFSDMEIPPATMRTLSTIAYNQPVLQSELFRARG---VRTYEDVRELMSMGFVAGRKT---GQTLELTTTKR----------------------------------------------- ->tr|A0A069K2J1|A0A069K2J1_9ACTN LysR family transcriptional regulator OS=Streptomyces sp. NTK 937 GN=DT87_29480 PE=4 SV=1 ---------------------------------------------------------------AERLGVSPGRVSQSIKKQERRigaPLFVRTTR-------TVRLSPLGEQLYQALKSGHRQITQGI---------------------------- ->tr|E2SQM6|E2SQM6_9FIRM Transcriptional regulator, GntR family OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_03545 PE=4 SV=1 ----------------------------------------------------------SVRAMASQIGVNPNTVAKAYQELEEQGYIYSEK----GKGCFVADNESDKLIREDKLKDFKGTVADMKQhHIEREELYKAID-------------- ->tr|W7CT63|W7CT63_9LIST GntR family transcriptional regulator OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_08280 PE=4 SV=1 ----------------------------------------------------------SIREYASMVGINPNTVSKAYQELERQHVILTIK----GKGAFVADKQNAVksiVDTQLSKQTLEATLLDFIYqGIDAEILKQWVD-------------- ->tr|A0A173XZS7|A0A173XZS7_9CLOT Uncharacterized protein OS=Clostridium paraputrificum GN=CP373A1_10020 PE=4 SV=1 ----------------------------------------------------------SVRKLSQELNVSTITIKRAYLELEKAGITYSVS----GVGTFVRVKDNEElinENKEKLFCELDDIVGKLLDgKCTKEEIIKRVN-------------- ->tr|A0A1J0A4K9|A0A1J0A4K9_9ENTE PadR family transcriptional regulator OS=Vagococcus teuberi GN=BHY08_02960 PE=4 SV=1 --------------------------------------------ELCVLYLLKNKDrygyELTQK-MNEHIVITEGALYPILRRLVKEEYCSTYlkESSSGPARKYYSLTDKGRQHLEKLFSEWNLFVESVQSLCQEED-------------------- ->tr|A0A1L8ZKN5|A0A1L8ZKN5_9BACI PadR family transcriptional regulator OS=Bacillus obstructivus GN=BLX88_13375 PE=4 SV=1 --------------------------------------------ELCVLILISKKDqygyELAQN-ISSKIEVAEGTLYPLLRRLTKDDLLTTYllESTEGPPRKYYSITTKGLEYMFDLISQWRQFSEAVNQFITEGM-------------------- ->tr|A0A160T459|A0A160T459_9CHLR HTH-type transcriptional regulator OS=Candidatus Promineofilum breve GN=CFX0092_A1597 PE=3 SV=2 ---------------------------------------GFSEVMGHLYGTLLLSPqPLSLDDLGDTLEISKGSVSMNMRDLERWGMAKEVWVRGERRKFY----------------------------------------------------- ->tr|A0A1S2W9E1|A0A1S2W9E1_9BACL Uncharacterized protein OS=Exiguobacterium sp. KRL4 GN=BLD48_05840 PE=4 SV=1 ---------------------------------------KLTKRQREVLYWRYEVD-LSQEMVSEISAVRQQSVDDVENAAFRD--------------------------------------------------------------------- ->tr|A0A1B7XPK4|A0A1B7XPK4_9FLAO Transcriptional regulator OS=Tamlana sp. s12 GN=VQ01_01055 PE=4 SV=1 ---------------------------------------QLAPVAARIFAYIVLTGksGTTFDNLVQVLCASKSTISTNLNHLQDLKKIEYFTKTGDRKKYFKVNDNSILQKIDEMIFNWTE--------------------------------- ->tr|H8I689|H8I689_METCZ Putative transcriptional regulator (IclR helix-turn-helix domain) OS=Methanocella conradii (strain DSM 24694 / JCM 17849 / CGMC ----------------------------------------LSGKYSDILELIDFRE-MSVSDISQALKINPGSAHYRLKELQRRGLVKMVREETKGNVVKKYYRAAARNIYLDGSKFK--ALRPGEASPMDGFYDRLIALLA----------- ->tr|Q0W5D1|Q0W5D1_METAR Uncharacterized protein OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=RCIX1094 PE=4 SV=1 ----------------------------------------CSPRYAEIIRIISGEE-FSVSDVARKLGANSGSVYYHMKELEKHGLVKLVREEIVGGVVKKYYRKAAMNFTFNISDPSSpSAAAAVAAGINEEFWEKLIKSLS----------- ->tr|A0A0J7Z976|A0A0J7Z976_9ACTN Uncharacterized protein OS=Streptomyces regensis GN=ACZ91_65045 PE=4 SV=1 ---------------------------------------------------ITPGTHLVEDTVAESFDVSRGPVRDALRMLRLENLVEPQR----RGVHVVGLSTTDVRELYAIRQAIEGlAVTTAIGLGEHRSGAGMAQALRGMADTATPTHA ->tr|A0A1B3NF70|A0A1B3NF70_9BRAD Uncharacterized protein OS=Bosea sp. RAC05 GN=BSY19_3933 PE=4 SV=1 ---------------------------------------------------FRNGERLNERHLAEMLGVSTTPVKDAIRKLESEGLVRTEAR---RGVFVEF-SARQALEMALGRAALESvMTHIAANRLGDADITEIGRLIEEMAHATQHSAL ->tr|I7FFX7|I7FFX7_MYCS2 GntR family transcriptional regulator OS=Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) GN=MSMEI_3867 PE=4 SV=1 ---------------------------------------------------FPAEGRMSVVSIAEQLKMSRSPVRAAVERLVTEGLLVVTA----VGIELAQLDHVDLIDGLRVRSRLEGlAARLTTDRLTDADLDRLRENLTQFDTAVRGGDT ->tr|A0A0G1ICS2|A0A0G1ICS2_9BACT Regulatory protein ArsR OS=Parcubacteria group bacterium GW2011_GWE1_43_8 GN=UW06_C0047G0006 PE=4 SV=1 ---------------------------------------------LEILLLLNRQAPLPLYQIAAKVRLSVKSTNKHLSQLLHTGFVAKNRQ---GLFVLYRLEDEAKPLVTKLLKLL----------------------------------- ->tr|A0A0G1LJI3|A0A0G1LJI3_9BACT ArsR family transcriptional regulator OS=Candidatus Giovannonibacteria bacterium GW2011_GWA1_44_25 GN=UW53_C0004G0001 PE=4 SV=1 ---------------------------------------------LKIMKLLFGCGEFTVTDISKEIGLSLKATSKHVIAMDNLGFVKNTGK---KGHVYYSIDLSQHTKVKELLKMI----------------------------------- ->tr|A0A0G1MYL7|A0A0G1MYL7_9BACT ArsR family transcriptional regulator OS=Parcubacteria group bacterium GW2011_GWC2_45_7 GN=UX17_C0020G0006 PE=4 SV=1 ---------------------------------------------LAILKAIVKHDELSVKMICQKLDKGVKLVSKHLGILAYMNIVEGQGK---LGSVWYKLHPSLRLEVKTIIHKF----------------------------------- ->tr|A0A0G1CB68|A0A0G1CB68_9BACT Transcriptional regulator, ArsR family OS=Parcubacteria group bacterium GW2011_GWD2_43_10 GN=UV57_C0027G0013 PE=4 SV=1 ---------------------------------------------LAIAVHLKRHHEATVGQLAALLKVSFPTASKHLSILAAADVVEYERR---SKEVYYYLADDIPAVASAILKYC----------------------------------- ->tr|A0A1G2L542|A0A1G2L542_9BACT Uncharacterized protein OS=Candidatus Sungbacteria bacterium RIFCSPLOWO2_01_FULL_47_10 GN=A2934_03795 PE=4 SV=1 ---------------------------------------------IAIIRYLKKEESAPVGEIASAIHLSFRSTSRHLRVLASSGILESEQK---GLTIRYGISSARGRIINTIISLL----------------------------------- ->tr|A0A1G2V4H6|A0A1G2V4H6_9BACT Uncharacterized protein OS=Candidatus Zambryskibacteria bacterium RIFOXYC1_FULL_39_10 GN=A2431_04320 PE=4 SV=1 ---------------------------------------------ILMLKILKKRNKISMGNMASQIKLSFRSTSKHFSILYTVGIVDREQH---GLTMYYSLSSKPSSIISQILSII----------------------------------- ->tr|A0A1G2D3D9|A0A1G2D3D9_9BACT Uncharacterized protein OS=Candidatus Lloydbacteria bacterium RIFCSPHIGHO2_02_FULL_50_13 GN=A3D65_03430 PE=4 SV=1 ---------------------------------------------LQIIRFLLKNKGMSVGEIAEEIETSLKSTSKHLLTLYHAEFLEKDRV---HGLTLYNLSGNLGDVERMAVNSI----------------------------------- ->tr|L8DBW1|L8DBW1_9NOCA Transcriptional regulator, AsnC family OS=Rhodococcus sp. AW25M09 GN=RHODMAR_1077 PE=4 SV=1 ---------------------------------------NIDRLDIELLGALSRNARMGIMELASTLGVARNTVQARLSRMIEEHYLAGFRPDIDLAEVGIAVQA------------------------------------------------ ->tr|A0A060HND0|A0A060HND0_9ARCH Putative transcriptional regulator, AsnC family OS=Nitrososphaera viennensis EN76 GN=NVIE_005260 PE=4 SV=1 ---------------------------------------DIDELDIRLVEILQKDSSTPSVKIAGMLRVTEGTVRNRVNKLRRLGVIRRFTISIDPMAMGQGAIA------------------------------------------------ ->tr|A0A1B1ZV97|A0A1B1ZV97_9PSEU AsnC family transcriptional regulator OS=Pseudonocardia sp. HH130630-07 GN=AFB00_01045 PE=4 SV=1 ---------------------------------------SLDALDVDLLAALRERPRAGALELSRVLTVARGTVQARLDRMERAGVITGYGPDVDLPAAGYGVQA------------------------------------------------ ->tr|A0A1S1NR53|A0A1S1NR53_9MYCO AsnC family transcriptional regulator OS=Mycobacterium sp. NE-TNMC-100812 GN=BKN37_00415 PE=4 SV=1 ---------------------------------------PIDSIDARILLLLFEHPRATTIAIADRAGISRNTAQSRIARLEASGALDSFERRVTPEALGYPLTA------------------------------------------------ ->tr|A0A0M0BN11|A0A0M0BN11_9ARCH Uncharacterized protein OS=miscellaneous Crenarchaeota group-15 archaeon DG-45 GN=AC482_05450 PE=4 SV=1 ---------------------------------------------LDILGIIGG-GTSKPTCIMYGANVSWEILQQTLAAMVSRGLVREIDARdarrRDRRtKTRYEITQKGEDIIRHFRRARG---------------------------------- ->tr|A0A1F5DM85|A0A1F5DM85_9ARCH Uncharacterized protein OS=Candidatus Bathyarchaeota archaeon RBG_13_52_12 GN=A3K78_06230 PE=4 SV=1 ---------------------------------------------QEILTHVHN-GNYLPTRLMHKTHISWVAFNRIKEPLISQGLLEEVED-pGDRRsRIKYRATEKGEKFLEYFGTAMK---------------------------------- ->tr|N9CUH4|N9CUH4_ACIJO Uncharacterized protein OS=Acinetobacter johnsonii ANC 3681 GN=F946_01379 PE=4 SV=1 ---------------------------------------------------LSKRGKTSVVDVQGMMGMTTRTVQRYLDQLVQAGYVLRD----DATPAGFIPSEKAKQLF------------------------------------------ ->tr|R5LU83|R5LU83_9SPIR D binding transcriptional repressor OS=Brachyspira sp. CAG:700 GN=BN758_01737 PE=4 SV=1 ----------------------------------------------NIIEFVYKNKNVTLDQICDNFNISKSTVRRDLSEILKDSNLQKTYGG------------------------------------------------------------ ->tr|A0A1Q2D7C8|A0A1Q2D7C8_9ENTE DeoR family transcriptional regulator OS=Vagococcus penaei GN=BW732_08495 PE=4 SV=1 ----------------------------------------------LMKHYILDRHFVSLKELERHFNVSMNTVRRDINQIIEDARFQKVYGG------------------------------------------------------------ ->tr|K2ER19|K2ER19_9ZZZZ ATP-dependent DNA helicase RecG OS=groundwater metagenome GN=ACD_21C00261G0003 PE=4 SV=1 -------------------------------------GEGSEISSEKILKCISKDKYISSKKISEAIGISPRAVEKQIAKLKSLGYLKRIGS---PKAGYWGIVTNRTKKNDK---------------------------------------- ->tr|X1JES4|X1JES4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_50807 PE=4 SV=1 -------------------------------------NEGVKFRLKKEISYLNTYKSIRRPNVERLFNISTATAERDLSILKRLNLIIFEGA---PKTGRYILTNKGKKILDS---------------------------------------- ->tr|D3EJ54|D3EJ54_GEOS4 ROK family protein OS=Geobacillus sp. (strain Y412MC10) GN=GYMC10_6270 PE=4 SV=1 -----------------------------------------SINQQKVLFLIYSEGPISRVELAEKTGLSRQTVTNIVNRLLKEKIiVTGELIdlEAGSGRKRVGLHINSGHFYAIGLELAGKYIRGKVFNLRQEAVASAERTSNK---------- ->tr|A7NGL7|A7NGL7_ROSCS ROK family protein OS=Roseiflexus castenholzii (strain DSM 13941 / HLO8) GN=Rcas_0477 PE=4 SV=1 -----------------------------------------NHNSRLVLRIIYEDEAISRADIARKTGLTRTTVSTVVGELIEQGLiEETGAGQSSGGRLPILLRVAHEAHSVLALSFEDTQIVGALVDMRGSIQRRVSLSLYG---------- ->tr|X0VS60|X0VS60_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H1_54145 PE=4 SV=1 ----------------------------------------------DLLVSLKPKDNLSIHRLSRETDITYTHLHRMLTEFERLGWITTYIE---GREKRIELTDTGKEMKNHALPIIIEL-------------------------------- ->tr|W1I3X7|W1I3X7_9BACT Uncultured bacterium plasmid pRGI01058 OS=uncultured bacterium PE=4 SV=1 ----------------------------------------LDSKQVDVLIFILENTKSsdntfigTYRKISEGANVALETVRKVMHKLQRqndqngIPFIKRIQNG------------------------------------------------------------ ->tr|A8MA70|A8MA70_CALMQ Transcriptional regulator, TrmB OS=Caldivirga maquilingensis (strain ATCC 700844 / DSM 13496 / JCM 10307 / IC-167) GN=Cmaq_0152 --------------------------------------IGLSKYQLRVYLTLVERGPLTAGLIAKYADVPSSKVYSVLKSMVRLGLIDVDSG---KRPEVFVAKP------------------------------------------------ ->tr|A0A1J5KGN8|A0A1J5KGN8_9FLAO PadR family transcriptional regulator OS=Flavobacterium sp. MedPE-SWcel GN=BM557_07405 PE=4 SV=1 ---------------------------------------------------------------KGKIDISEGALYPILHKMEADKILETEKIYIGKRvRKYYQITQSGKKVALEITNELNDFISTLSLIFNDK--------------------- ->tr|A0A1C7GSP3|A0A1C7GSP3_9FIRM Uncharacterized protein OS=Ruminiclostridium sp. KB18 GN=A4V00_16940 PE=4 SV=1 ---------------------------------------------------------------EGKLRLIENSLYGTVYRLQREGYISSKKEENVARaRVFYHLEPSGEVYLAKLIKEYESISEGIRLVIGNP--------------------- ->tr|A0A0K3B3M0|A0A0K3B3M0_9PSEU Transcriptional regulator, HxlR family OS=Kibdelosporangium sp. MJ126-NF4 PE=4 SV=1 -----------------------------------------------VMLVLREalLGTTRFEQFRTILEVADNVLSRRLTDMVDAGLLRRSRYQGKQRaHDEYVITEAGADLLPVLDALA----------------------------------- ->tr|M0NFF8|M0NFF8_9EURY Uncharacterized protein OS=Halococcus thailandensis JCM 13552 GN=C451_01743 PE=4 SV=1 ---------------------------------------------GEILWAINDQP-RTKPALTEALDTSRSTINRGVDELEEAGCIERRDS-------KYYTTLLGELSCTRYRNYRSNMSA------------------------------ ->tr|R8CLC5|R8CLC5_BACCE Uncharacterized protein OS=Bacillus cereus HuA2-9 GN=IG9_05494 PE=4 SV=1 ------------------------------------------------------------------YKSSFGSLYPALKRLEEKEWVSVKNVKGDSKnKKNYTIQNAGKVALFKWLEQPLQTTKnehlvkiFFIDYLEKDKrSNLLKEFYYHLKNQKSKLQQ ->tr|A0A0W8E581|A0A0W8E581_9ZZZZ Transcriptional regulator, padr family OS=hydrocarbon metagenome GN=ASZ90_018770 PE=4 SV=1 ------------------------------------------------------------------YNASYGSIYPILKKQEEAGLVSVEELVEGGRfKKIYQLTEKGRNTFLQWLEEPPQPITikndmlvrlFFFNNVTREKqVEITEIYLDHLKDFRQRLDD ->tr|A0A1D9P0N0|A0A1D9P0N0_9FIRM PadR family transcriptional regulator OS=Butyrivibrio hungatei GN=bhn_I1007 PE=4 SV=1 ------------------------------------------------------------------WKGSFGSIYPALGEMEKQELVKRKKSdKSSGReKIVYQITKDGKETLKAWLNDEKAINDlkyetllkmYFGGIQDRSVtIRNIEIFEQQVKENLEVLKF ->tr|A0A1F6PTI5|A0A1F6PTI5_9BACT Uncharacterized protein OS=Candidatus Melainabacteria bacterium GWA2_34_9 GN=A2039_01995 PE=4 SV=1 ------------------------------------------------------------------LSASFGSIHPAMKKLEKNGYISAKRKmSSGGQkSSTYSITIEGKEHFKKLMTSEINESPtysnqlinikmMLLDLLDENLrKNTINLIKKYYEIHLltarELLET ->tr|A0A1W1H9H9|A0A1W1H9H9_9DELT Transcriptional regulator (PadR family protein) OS=Desulfamplus magnetovallimortis GN=MTBBW1_1680008 PE=4 SV=1 ------------------------------------------------------------------FNTGFSSIYPKLKKLEKEERVRVSQVIKNGKlNKLYTLTDEGKKAFLEWLEIKPEIGRirdeallkvFFFDHLEDDKiVPQLKGYVGDLSQHVQNLLS ->tr|A0A1N6Z7U2|A0A1N6Z7U2_9BACI Transcriptional regulator, IclR family OS=Bacillus simplex GN=SAMN05878482_10366 PE=4 SV=1 ---------------------------------------------LDVLSYFTAETpEWGLRDLARKMEMNHTVLHRILKTYENKGYLIQNESTK----------------------------------------------------------- ->tr|D3ADZ4|D3ADZ4_9CLOT UbiC transcription regulator-associated domain protein OS=Hungatella hathewayi DSM 13479 GN=CLOSTHATH_01823 PE=4 SV=1 ----------------------------------------------------------AEMEFCEFCSVSRPTVRQALSELVSEGYLTRLK----GKGTYVSRPKIQAMFFNRLLSFNEEMKER----------------------------- ->tr|D1AQI9|D1AQI9_SEBTE Transcriptional regulator, GntR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3410 PE=4 SV=1 ----------------------------------------------------------KELDLCKIYNVSRPTIRKAMDILVQNGNLIRIK----GKGTYVSSdKKIKQEFTHIIQNFNAEMSQK----------------------------- ->tr|A0B595|A0B595_METTP Transcriptional regulator, PadR family OS=Methanosaeta thermophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT) GN=Mthe_006 --------------------------------------------DILILSILGERPMCGydlIKEIYRRYNVllSQGAVYPILYSMVDDGILRSEYSRGNMRTKIYTLTPKGQEVMRRKIGKMVYALEYMLSFLKGSCSE------------------ ->tr|A0A0Q9IGA4|A0A0Q9IGA4_9BRAD Uncharacterized protein OS=Bosea sp. Root381 GN=ASE63_20065 PE=4 SV=1 ---------------------------------------------------LRPGDRINENQLSIELDVSRSLIRQALRSGELSHLVEIVHN---KGAFVRKPDLTTIFDLYDVRAGLAYTAGKILArRATMEQIAELYALYEEMEARREAKDP ->tr|A0A1H5SMV5|A0A1H5SMV5_9EURY Winged helix-turn-helix DNA-binding OS=Halobellus limi GN=SAMN04488133_0019 PE=4 SV=1 ---------------------LRRRYEDAATTVFMEAASKLTTAVHDILATVVQENGATYDKLEEVTGLARSTVRYHVARLAEKGVLKRIGNP------------------------------------------------------------ ->tr|A0A0N0BNQ5|A0A0N0BNQ5_9EURY Uncharacterized protein OS=Haloarcula rubripromontorii GN=AMS69_10250 PE=4 SV=1 ---------------------MEEANEERERKILKTTYESLSAAKWDILWTVAVTEGCSYETLEEITGFSYDYVREVVQELESMDILLRVTYP------------------------------------------------------------ ->tr|K7QZ58|K7QZ58_THEOS Transcriptional regulator OS=Thermus oshimai JL-2 GN=Theos_2421 PE=4 SV=1 ---------------------------------------------LLILRALHERGqATAGELRALFGGRSLRSVYDLLRVLEEAGLVVRLARR-KGWTLAYPHPFFTAQQ---E--------------------------------------- ->tr|A0A0C2RK62|A0A0C2RK62_MICLU Uncharacterized protein OS=Micrococcus luteus GN=OC70_07895 PE=4 SV=1 ---------------------------------------------FALLDVVATDSrGMTAKEIAAALQMPLPTVYRMLKTLVASGHVVHLREE-SRYGLGYKLHALDTSLRRQV--------------------------------------- ->tr|A0A1F1W937|A0A1F1W937_9MICO Transcriptional regulator, IclR family protein OS=Brachybacterium sp. HMSC06H03 GN=HMPREF3159_14245 PE=4 SV=1 ---------------------------------------------IAVLEAVAEHGSSTARRISEATSIPLPTVYRIAQELIRSEYLVHLRTE-KRFALGYKLHRLAVGLHDDL--------------------------------------- ->tr|A0A1J4N913|A0A1J4N913_9ACTN Uncharacterized protein OS=Nocardioides luteus GN=UG56_004695 PE=4 SV=1 ---------------------------------------------ANTLAIISENPaGVSAKVLARRLEQSLSTTYYALQTLTDVGMIEHSPTTSGLYTLGPQIAALYRGYVANR--------------------------------------- ->tr|A0A1M5EPV2|A0A1M5EPV2_STRHI Transcriptional regulator, IclR family OS=Streptoalloteichus hindustanus GN=SAMN05444320_10578 PE=4 SV=1 ---------------------------------------------MDVLEAVAAADePISAKALARAVGCGLSTVYNLIAVLTGRGYLART--S-AGYVLGHQVSGLNRAFSRQM--------------------------------------- ->tr|E1QRL2|E1QRL2_VULDI Transcriptional regulator, ArsR family OS=Vulcanisaeta distributa (strain DSM 14429 / JCM 11212 / NBRC 100878 / IC-017) GN=Vdis -----------------------------------------NNVRISIMDMLSR-GPMTVTSLAQELGMLKGVVHRHVKALEDFGWIRQLSN---DEVKVMGLSREANRIY------------------------------------------ ->tr|A0A1X1W7N2|A0A1X1W7N2_9MYCO Transcriptional regulator OS=Mycobacterium iranicum GN=AWC12_27785 PE=4 SV=1 -----------------------------------LATWRLPRSTGRVYGYLLLRGdASSTEELCSRLHLSAGAVSTATRELVSWGLARTLPQAGSRRL------------------------------------------------------- ->tr|A0A0B8NEW1|A0A0B8NEW1_9NOCA Uncharacterized protein OS=Nocardia seriolae GN=NS07_v2contig00147-0010 PE=4 SV=1 ---------------------------------------------LRVIWELEP-GPLGFLELRRRMgNCSSSMLSVRLQRLTETGVVTKNADK------SYELTTVGKQLGLALESVWQ---------------------------------- ->tr|A0A1U9YWF4|A0A1U9YWF4_9RHIZ Cyn operon transcriptional activator OS=Martelella mediterranea DSM 17316 GN=cynR_5 PE=4 SV=1 ----------------------------------------HDIWRFQHFLGVVDAGSFHGA--ARAMNISQPALTKSIRLLEEAfgtELFLRLPR-------GVRLTEAGEMMHIRAREVEAAWNAAI---------------------------- ->tr|A0A1Y5TSP2|A0A1Y5TSP2_9PROT HTH-type transcriptional regulator CynR OS=Oceanibacterium hippocampi GN=cynR_4 PE=4 SV=1 ----------------------------------------IGLRKLRHVVETARFESVTRA--ADALLITQSALTRSIAEVEAElgiQLFVRLPR-------GVRTTEAGRSFVEKALRIIGDVNSLV---------------------------- ->tr|G0A909|G0A909_COLFT Transcriptional regulator, ArsR family OS=Collimonas fungivorans (strain Ter331) GN=ydfF PE=4 SV=1 ------------------------------------------PTRIQMLALLMEGRALTAKELAYGTDIKPATATAHLRQLVDDKLLDMTSQ---GRHKYFRLASP----------------------------------------------- ->tr|A0A0R1UZM1|A0A0R1UZM1_9LACO Transcriptional regulator, ArsR family OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL000674 PE=4 SV=1 -----------------------------------------NAQRTKILLFLLDNRFHTVNEITQKTDLKNNTVSFHLGKFLKAAWVICTVK---GKFHYYRLKNA----------------------------------------------- ->tr|A0A1B9L878|A0A1B9L878_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G11_09570 PE=4 SV=1 -----------------------------------------DANRVMIISELMNGRSLCASWLAKQLNLSPSATRFHLKKLEDAQLIHQRTC---GKHHYYEIKNQ----------------------------------------------- ->tr|G5HLP2|G5HLP2_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_03504 PE=4 SV=1 ---------------------------------------------FKILEVLAKnPEGLSLLALSEQTGLPSSTVHRLLHTLFALGYTEWRSSNSSPYKLTLRLFEYGCYSVenRTFIQKAHPFIKRLSEEL------------------------ ->tr|A0A1V5VBB0|A0A1V5VBB0_9BACT Acetate operon repressor OS=Lentisphaerae bacterium ADurb.Bin242 GN=iclR_1 PE=4 SV=1 ---------------------------------------------FQILEMLYEnknpDDGLGIASVSRELGLKLPTVHNLMKTLVLLGYAEQK--EDGKYRPGPKADKFGMKSDSRLLALARPLIARLVREL------------------------ ->tr|A0A081P7L1|A0A081P7L1_9BACL Uncharacterized protein OS=Paenibacillus tyrfis GN=ET33_33135 PE=4 SV=1 ----------------------------------------------RLHQVMKENPRASQRELAKILGCSPAWVSKLIRGLQMDRAKHHikGVLDDD---------------------------------------------------------- ->tr|A0A151F6Q4|A0A151F6Q4_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon DG-70 GN=AYK18_02400 PE=4 SV=1 -----------------------------------------HAHRLRILVLLLN-GPQELSHLLDAVKISKTALANHLTHMMDKGVIERSERG------TYQITADGKDLITAVATFYEQSTARELN-------------------------- ->tr|A0A1Q3YMG3|A0A1Q3YMG3_9BURK Uncharacterized protein OS=Burkholderiales bacterium 70-64 GN=BGO72_13875 PE=4 SV=1 ---------------------------------------------LALLEAFDrETPALGVTQLAAKVGLHKSTAYRLATTLAGEGFLHQDRA-TGRYSLGGRFYRIAAGFVEQD--------------------------------------- ->tr|A0A1M6CS92|A0A1M6CS92_9ACTN DNA-binding transcriptional regulator, IclR family OS=Nocardiopsis flavescens GN=SAMN05421803_101797 PE=4 SV=1 ---------------------------------------------LQIIFAVAeaEGPDMGVSELARSLNLSKTVVHRVVRTLVDDGFFQMDER-TRRYRLGPAAVSVGLSALARM--------------------------------------- ->tr|A0A0Q4FLJ7|A0A0Q4FLJ7_9FLAO Uncharacterized protein OS=Chryseobacterium sp. Leaf201 GN=ASE55_00770 PE=4 SV=1 ---------------------------------------------FSILLELHYHEKLRFKDFFEVLkGISPKVLSSELSLLEVHRLIQKNIEYTpTQDITYYALTEHAQEIWTVLNTLID---------------------------------- ->tr|A0A1Q6A6J9|A0A1Q6A6J9_9SPHI Uncharacterized protein OS=Mucilaginibacter polytrichastri GN=RG47T_5118 PE=4 SV=1 ---------------------------------------------IMIIASLSVFGEKRYTELQRIIdGIGTKMLSKELQELEINGLIKRTVMPTKPVTVKYELTAYGSTLKPIIDEMAS---------------------------------- ->tr|A0A1M4T3G9|A0A1M4T3G9_9SPHI Transcriptional regulator, HxlR family OS=Pedobacter caeni GN=SAMN04488522_10169 PE=4 SV=1 ---------------------------------------------MYVIIAIYNG-NHRYREIARSIsGITFAMLSRELESMALNKLIIRTEDPDFSKDVKYTLSAYCQSIYPLVESLID---------------------------------- ->tr|A0A061NW37|A0A061NW37_9BACL Transcriptional regulator, GntR family OS=Geomicrobium sp. JCM 19038 GN=JCM19038_2036 PE=4 SV=1 ---------------------------------------------------LTPGEKLSFRKVAHNYNVSMMPVREAMTRLHVQDLITINK----KTIRIKKLTASEVEDIFQMRFKLEAmAVEKAMFNIGDQEKDELLNTIAAM--------- ->tr|A0A1Q3SPM4|A0A1Q3SPM4_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_14165 PE=4 SV=1 -----------------------------------------------IVLAGKTPRRLSDIAIAAELRISRTPVRQALDRLAQEGLVHFDPR---RGFWTHVYTAEDVEEIYQIREATEVlALRLAAPRLKQAELENHLKTLLDIRATLPNPH- ->tr|A0A1Q5B2K2|A0A1Q5B2K2_9ACTN Uncharacterized protein OS=Micromonospora sp. CB01531 GN=A6A27_24520 PE=4 SV=1 -----------------------------------------------LAGELAPGTLYSVVELSNQLGVSRTPVREALLQLASNGMVRFERS---KGVRILELSTQDIEEIYMLRIFLEApAAYRAAQHMPQEHREAFQSAFAGMRAACEAGN- ->tr|A0A1Q4UQY2|A0A1Q4UQY2_9PROT GntR family transcriptional regulator OS=Thalassospira sp. TSL5-1 GN=LF95_15115 PE=4 SV=1 -----------------------------------------------REGRLAPGQRLTEAEFTRKLAVSRPTIREAFRQLCNDGLLQFEPH---RGASVRQLTRHELDDLFVIRASLEAlAVRLSAPLLEQApgPLLQIQASLDKAEQEGDRKK- ->tr|A0A1P9Y2H5|A0A1P9Y2H5_9BURK Uncharacterized protein OS=Burkholderia sp. KK1 GN=A9R05_21780 PE=4 SV=1 -----------------------------------------------RLGQFAGGHRLIEGDLAAELDVGRGSVREALRILAGDGVIELVPH---KGASVRRLNQGELIQIFEALTATHWeAVRICARRFEE-peIQQSISASLKRVEQVRRAEE- ->tr|A0A1V2ALY5|A0A1V2ALY5_RHIRD GntR family transcriptional regulator OS=Rhizobium radiobacter GN=BV900_11275 PE=4 SV=1 -----------------------------------------------VSGRLHGGERLLPNELAADLGISPTPVKEACLKLEADGLVVNSSR---RGMVVRDFTVEDVEELYAARMLLEKgAVEVAFDAGQLDeaLHAQLLESLAKHREFAKSaTL- ->tr|A0A089HVL7|A0A089HVL7_PAEDU Uncharacterized protein OS=Paenibacillus durus GN=PDUR_22590 PE=4 SV=1 ----------AYDDIKQRPQLCVTLLRMVLSRYRPSAApvsr--AVLAEKEVLRLAIHAAkPLRPVDVARHFEVDSKTAVQILKKLCAKGLLNPVRRGKSERAVGYELSNGVLDYY------------------------------------------ ->tr|E0I786|E0I786_9BACL Putative uncharacterized protein OS=Paenibacillus curdlanolyticus YK9 GN=PaecuDRAFT_1510 PE=4 SV=1 ----------SVDDLEEQQRRCQQMLMHILGKWYGSAGnatllEQLTPRENQLLNIIVEKGtVMTPKQVANETGMHQAYVRRLLKSMVEKGYLQPV-G-GAlaTRIRSYKPTFVYERNK------------------------------------------ ->tr|A0A0Q9TN35|A0A0Q9TN35_9BACL Uncharacterized protein OS=Paenibacillus sp. Soil787 GN=ASG93_24920 PE=4 SV=1 ----------AYDDVKNRPRMCEQLLQQCIGRHFGDVFnqeIELNFIEKEIIRFGLTLGrPIKPTDVQKQFQFRQRKAQETLKGMYQKSLLEPVGA-GHARVRGYSVAQH-VLAS------------------------------------------ ->tr|A0A0B0I218|A0A0B0I218_9BACL Uncharacterized protein OS=Paenibacillus sp. P1XP2 GN=CM49_01169 PE=4 SV=1 ----------AYLSIRDDPGVCKQLVLSFVGKFLSS-AvpFGLHWAEAETLRYAHRLLrPFTPMELSSHLQLSEHRTRVILRALLEKKLL-EVASG-KQRYRTYRLPGDHVQSP------------------------------------------ ->tr|A0A089K9W1|A0A089K9W1_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL R7-0273 GN=R70723_08285 PE=4 SV=1 ----------PYDDLESASDLTISLFKSLLAPSLLINTdeleHHYTRLERDIMRAVVRWNgMIRPVDLANGLRVHPRTIRKSLTRLCEKGKLRPVPASGSSRICRYEYVPSIMNNG------------------------------------------ ->tr|C6CV44|C6CV44_PAESJ Uncharacterized protein OS=Paenibacillus sp. (strain JDR-2) GN=Pjdr2_0878 PE=4 SV=1 ----------SAWQVEHQPQQCIVKVKQAIGHWWSLTYqrdlkqttNIWEIRKQWIIQMALRQQgKIRPGDVAQEFQISNRTAVDWLHRLETAKLLQRLP--AKHRVTTYVLADYVAST------------------------------------------- ->tr|A0A197ZYC1|A0A197ZYC1_9BACL Uncharacterized protein OS=Paenibacillus sp. 1ZS3-15 GN=A8708_25130 PE=4 SV=1 ----------SLDDIRERPRLWQALLQQLIGRLFGEHEstaSHLSGQERDILRLALRMDrPIKLADVKDVLCCGYDTARKYIKRLEEKKWLLPEVK-GAARIHTWIVDTTRRPPL------------------------------------------ ->tr|C6CW25|C6CW25_PAESJ Uncharacterized protein OS=Paenibacillus sp. (strain JDR-2) GN=Pjdr2_1213 PE=4 SV=1 ----------SYDDICDRPRMCEQIVQQFMSTWLDRHYterSSDAIIQHEVLRLALRTEkPLRAREVSTYLTVHIETARSILRELAKLNLLLPCGG-GKQRVHSYVVNKENL-DD------------------------------------------ ->tr|A0A0P9CAI7|A0A0P9CAI7_9BACL Uncharacterized protein OS=Alicyclobacillus ferrooxydans GN=AN477_17520 PE=4 SV=1 ----------TYHDITTSARQCEHIIRQARGDIIARS-tafKDTTPYERDIIRLAIRSTqPITAQDVRSYLNISRDYSFNLLHGLTERKWLLPSR--GTRRINSYVLHPSKRNIR------------------------------------------ ->tr|L0EC79|L0EC79_THECK Uncharacterized protein OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=Theco_0580 PE=4 SV=1 ----------SYDDICGRPQLCRTVIQKLLGLCYGADDk-SLPLPQRELIRRAMRHGrPFTPDDAAEWTGLSKRTVGPMLHRLRMQGYVEPA-S-GKVRIRRYALTLKAERLG------------------------------------------ ->tr|A0A1C0ZW30|A0A1C0ZW30_9BACL Uncharacterized protein OS=Paenibacillus pectinilyticus GN=A8709_31280 PE=4 SV=1 ----------SLDDVKNRPRMCEQILQQCIGKYFGDFFsqdHSMSYIEREIIRLANSIEkPIRPVDIQKSFQFGQGKSQRILKAMCAKAFLKPAGQ-GTSRIRSYSVNQTLVLAS------------------------------------------ ->tr|A0A1C1A5F0|A0A1C1A5F0_9BACL Uncharacterized protein OS=Paenibacillus pectinilyticus GN=A8709_14050 PE=4 SV=1 ----------SLDDIKYNPRKCQQTIMQAAAKWGLDDTkhlLQLIPTEYAVWKWVENQDdLVTPISVAKALRINRETSTKYLKSLVLKGLILPASR-EGKKIMRYRAKSSGRTNG------------------------------------------ ->tr|A0A1I7G6C9|A0A1I7G6C9_9BACL Uncharacterized protein OS=Alicyclobacillus macrosporangiidus GN=SAMN05421543_10223 PE=4 SV=1 ----------PTHDLANNPRHCQQTIQQLFGRLFSTQNesfHELNSLDREILRIFSKWPdLMGPKRIAELLHVSSDTASRHLRNLASKRWLDPLG--GKQRVRLYRLNPNRRLDR------------------------------------------ ->tr|A0A1Y5KJ01|A0A1Y5KJ01_9BACL Transcriptional regulator OS=Paenibacillus sp. MY03 GN=B1748_00775 PE=4 SV=1 ----------AYLSIRDEPEFCKQLLLSFVGKFLSI-NvdAGLNGLEAETVRFARRKLrPFTPNELAEHLRITDRYARMLLHRLVEGQQI-TVVGG-NIRFRTYQLNMGGLLGP------------------------------------------ ->tr|A1B2F6|A1B2F6_PARDP Transcriptional regulator, LysR family OS=Paracoccus denitrificans (strain Pd 1222) GN=Pden_1600 PE=4 SV=1 ----------------------------------------MDINHLRTFVTVVREGSITRA--SEILYRSQPAISAHIKSMEDSlgiKLFERNPR-------GMTVTQGGSRLLAVADKLLEQHQRFL---------------------------- ->tr|W0H4B3|W0H4B3_PSECI Transcriptional regulator OS=Pseudomonas cichorii JBC1 GN=PCH70_21240 PE=4 SV=1 ---------------------------------------------IQAFEQTARFGNVARA--AEQLNLTPSAVSHQLAKLESMIGRQLFL----RTARGVSLTPVGEQYLSEISGILHSFAVATERAASDISLDCLR--------------- ->tr|A0A1S1FPP0|A0A1S1FPP0_9PAST Transcriptional regulator OS=Haemophilus sp. HMSC61B11 GN=HMPREF3263_06720 PE=4 SV=1 ---------------------------------------------LKSFESAARHLSFTKA--ADELFVTQAAVSHQIKLLEDFLGVELFI----RKNRSLELTEFGKAYFVDINKVLRKLNEATERLLTLKAEPHLA--------------- ->tr|A0A0A7SZF1|A0A0A7SZF1_LACLL DeoR faimly transcriptional regulator OS=Lactococcus lactis subsp. lactis GN=E34_1882 PE=4 SV=1 --------------------------------------------KRRIVDYLKLKRRATIEELLTLMDCSISTLRRDLNELEKEKSLRRVHGG------------------------------------------------------------ ->tr|A0A226C5J2|A0A226C5J2_ENTFC DeoR family transcriptional regulator (Fragment) OS=Enterococcus faecium GN=A5848_001456 PE=4 SV=1 --------------------------------------------QERIITLLEKDFYLTNSEIANKLGVSEMTIRRDVTELAKKNKVKKLYGG------------------------------------------------------------ ->tr|A0A1C4UKQ8|A0A1C4UKQ8_9ACTN DNA-binding transcriptional regulator, PadR family OS=Micromonospora chaiyaphumensis GN=GA0070214_101786 PE=4 SV=1 -----------------------------------------------ILVSLLEQP-ASGYELARRFDRsigrfwtaTHQQIYRVLKRMEHDDWLTAEEVGQEGLpdKKVWSVTPTGRSALVA---------------------------------------- ->tr|A0A0N0KCD0|A0A0N0KCD0_9SPHN Uncharacterized protein OS=Novosphingobium sp. AAP83 GN=IP81_18090 PE=4 SV=1 ----------------------------------------ISFQQLRLFESVGRLESVRKG--SDECNLSQPAVTQALSKLERQvgfALLERRAS-------GSYLTEAGTVLHLRVCRMFAQMASAVMAIGEAKGVEQASVIVNRL--------- ->tr|W6VWU5|W6VWU5_9RHIZ Transcriptional regulator, LysR family OS=Rhizobium sp. CF080 GN=PMI07_001929 PE=4 SV=1 ----------------------------------------PNLRHLRMLQVIGRTQGIGSA--AREMNTSQPAVTLAVATVESElgiEVFERGGS-------GTFPTSAGRLLLARVSRFFDILEAALLRVAG-DAApqRRpLPPVERVM--------- ->tr|A0A0C2TM58|A0A0C2TM58_BACPU Uncharacterized protein OS=Bacillus pumilus GN=B4127_1288 PE=4 SV=1 -------------------------------------------------AHLYYTDGWTQQEIAKKLNVSRPVISKLLQKAKDVGIVEVYIKDESIHTVELE--------------------------------------------------- ->tr|A0A0K8JGR9|A0A0K8JGR9_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_2907 PE=4 SV=1 -------------------------------------------------LNMHFIEGLTQSQIAKAFHVSNTIISRKINKARDYNLIDYFFKDETSFTVNLE--------------------------------------------------- ->tr|F2J6A0|F2J6A0_POLGS Putative LysR family transcriptional regulator OS=Polymorphum gilvum (strain LMG 25793 / CGMCC 1.9160 / SL003B-26A1) GN=SL003B_ --------------VVARAARALGYIREAAQRIArrcrsegsstpDLLETHATISHLRAASLVAHTGSFSAA--ARALGQSEPSVHRAAREIEGILGVTLFD----EAYRRLQTTPAGRTLATAASLVLKELDN------------------------------ ->tr|A0A0Q6X8E0|A0A0Q6X8E0_9BURK Uncharacterized protein OS=Rhizobacter sp. Root1221 GN=ASC87_21430 PE=4 SV=1 --------------IAQRAQRLFDHLEAGATEAValmpegegrdgmqGRFCASVSAASLKALVAIAASASEAHA--AQALGQSQPSVHRALRDLESLARARLLW----KSVRGTRLTDAGEAMLRRVKLAFAEMRA------------------------------ ->tr|A0A0T6YTS4|A0A0T6YTS4_9RHIZ Uncharacterized protein OS=Sinorhizobium sp. GL2 GN=N182_21440 PE=4 SV=1 --------------YLLRIDRFFEILDNALAHAMgrlgdapdrmPKVERLMTGTQLRALVVTCEQGRVREI--AHSLGLSPASLFRSARSLEHALGKPLFD----RTAQGPIPNRTGNFLAREFRRAIREIEM------------------------------ ->tr|A0A198UE06|A0A198UE06_MORCA Transcriptional regulator associated with utilization of aromatic, LysR family OS=Moraxella catarrhalis GN=AO384_1987 PE=4 SV=1 --------------YVNRVKRSLAILKYGLIDVLrmqdfgiqksDYLFHHLTNTQLKAFITVAETSNYTHA--AKKIGTSQSSVYRSIQELQHLLNLKLFE----KTSLGLKLSKIGLIFYQSCKLATAELAQ------------------------------ ->tr|F7X832|F7X832_SINMM Transcriptional regulator OS=Sinorhizobium meliloti (strain SM11) GN=fldY PE=4 SV=1 --------------LLMRLRRMENQIASALAELFgvssqrdptlvAKCLARIGFRQIEALIALSGSGSITEA--ARSGGGSPAALHRALHDLQTNIGRAILM----RSPAGVAPNALGRRLAIRWQVALTELEQ------------------------------ ->tr|A0A1J0RZA1|A0A1J0RZA1_9ALTE LysR family transcriptional regulator OS=Alteromonas mediterranea GN=BM524_00460 PE=4 SV=1 --------------FLTRANRAFEHLHEFAFTLYstdkrkrQSLVRSITSRQLNSFVKVAETHSYTIA--AARLGLSQPTLHKSIKNLETLCEQSLFH----RSPAGVEPTWRARQLRRFANLFIAEIQQ------------------------------ ->tr|A0A1E3ZDG6|A0A1E3ZDG6_9BORD Uncharacterized protein OS=Bordetella sp. SCN 67-23 GN=ABS43_13600 PE=4 SV=1 --------------LHRRTELAFAELQQACDVLSarypesaprlrtaPFFFLAVHERRLELLFAFTERKHISTA--AAAVGVSQPAASMALYDLEASVGVPLFD----RAHAGVALNESGELLLAHVKRALAQLRL------------------------------ ->tr|A0A1E4GG92|A0A1E4GG92_9RHIZ Uncharacterized protein OS=Pelagibacterium sp. SCN 64-44 GN=ABS76_07545 PE=4 SV=1 --------------AYRRVSRFHRELGEAVMGVGagaqdae-QRLSRITNLHISTHLAMADDPMLAFV--PQALGVMPATSLRAIRELERTLGAQLYE----QTSEGRVVTRKGRELARQLGLAVREIDL------------------------------ ->tr|A0A1Y0L8B9|A0A1Y0L8B9_TATCI LysR family transcriptional regulator OS=Tatumella citrea GN=A7K98_11210 PE=4 SV=1 --------------ILPRARRAIEELHQVAVTLHklqskngnsrsmTEPLYLFNVNRLQIFVSLCQTRHMQTV--AKLLGLSQPAVSAALRVMENGAEMPLLQ----RTPQGMIPGIAGQEILPYIRRALNELRH------------------------------ ->tr|A0A081BWG4|A0A081BWG4_9BACT Uncharacterized protein OS=bacterium UASB270 GN=U27_03632 PE=4 SV=1 ------------------------------------------NTRLRIVWLLKRAGtALCVCEIMDALHESQYNISRHLKELRIAGVVQDQKQ---GRWNFYTLADSSSQFEQLVLQAVAALTSDALEL------------------------- ->tr|Q5E1H7|Q5E1H7_VIBF1 Transcriptional regulator, ArsR family OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=VF_A0049 PE=4 SV=1 ------------------------------------------PNRLRLFWLFLHVDeCIAVAEALDIIGDTQYNVSRNLKMLYRAGLLNHQKK---GKWVFYTLKEQAAPHCKALVDSVRFLPKDEFEE------------------------- ->tr|A0A1G3KSF4|A0A1G3KSF4_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_27_13 GN=A2Z98_04980 PE=4 SV=1 ------------------------------------------ETRIRILKVIIQSKtELCVCEIVDSLQIPFYTISKHIKELKNAEILSETKE---GKFVLYSFVDKKDDFLNKIIDLIKSIPDEFFSN------------------------- ->tr|A0A1F7SNS6|A0A1F7SNS6_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium RIFCSPLOWO2_12_FULL_38_15 GN=A3G31_01865 PE=4 SV=1 ------------------------------------------ENRLRIFNLVLLSNqEIFAGEISNALKKPQYTISRHIGILIKSGLIKQRRD---GARIFYSLSEKTKELRINLLQFLDMiggDFQNIFKE------------------------- diff --git a/esm/examples/contact_prediction.ipynb b/esm/examples/contact_prediction.ipynb deleted file mode 100644 index 58a71a9..0000000 --- a/esm/examples/contact_prediction.ipynb +++ /dev/null @@ -1,290 +0,0 @@ -{ - "cells": [ - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "# Contact Prediction Examples\n", - "\n", - "This example shows contact prediction with the ESM-1b and MSA Transformer models. Contact prediction is based on a logistic regression over the model's attention maps, without any finetuning of the language model. This methodology is based on our ICLR 2021 paper, \"Transformer protein language models are unsupervised structure learners.\" (https://openreview.net/pdf?id=fylclEqgvgd). A pair of amino acids is defined to be in contact when Cb-Cb distance is within 8 angstroms. " - ] - }, - { - "cell_type": "code", - "execution_count": 2, - "metadata": {}, - "outputs": [], - "source": [ - "import matplotlib.pyplot as plt\n", - "import esm\n", - "import torch\n", - "import os\n", - "from Bio import SeqIO\n", - "import itertools\n", - "from typing import List, Tuple\n", - "import string" - ] - }, - { - "cell_type": "code", - "execution_count": 3, - "metadata": {}, - "outputs": [ - { - "data": { - "text/plain": [ - "" - ] - }, - "execution_count": 3, - "metadata": {}, - "output_type": "execute_result" - } - ], - "source": [ - "torch.set_grad_enabled(False)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## Data Loading\n", - "\n", - "This sets up some sequence loading utilities for ESM-1b (`read_sequence`) and the MSA Transformer (`read_msa`)." - ] - }, - { - "cell_type": "code", - "execution_count": 4, - "metadata": {}, - "outputs": [], - "source": [ - "# This is an efficient way to delete lowercase characters and insertion characters from a string\n", - "deletekeys = dict.fromkeys(string.ascii_lowercase)\n", - "deletekeys[\".\"] = None\n", - "deletekeys[\"*\"] = None\n", - "translation = str.maketrans(deletekeys)\n", - "\n", - "def read_sequence(filename: str) -> Tuple[str, str]:\n", - " \"\"\" Reads the first (reference) sequences from a fasta or MSA file.\"\"\"\n", - " record = next(SeqIO.parse(filename, \"fasta\"))\n", - " return record.description, str(record.seq)\n", - "\n", - "def remove_insertions(sequence: str) -> str:\n", - " \"\"\" Removes any insertions into the sequence. Needed to load aligned sequences in an MSA. \"\"\"\n", - " return sequence.translate(translation)\n", - "\n", - "def read_msa(filename: str, nseq: int) -> List[Tuple[str, str]]:\n", - " \"\"\" Reads the first nseq sequences from an MSA file, automatically removes insertions.\"\"\"\n", - " return [(record.description, remove_insertions(str(record.seq)))\n", - " for record in itertools.islice(SeqIO.parse(filename, \"fasta\"), nseq)]" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## Run ESM-1b Contact Prediction" - ] - }, - { - "cell_type": "code", - "execution_count": 5, - "metadata": {}, - "outputs": [], - "source": [ - "esm1b, esm1b_alphabet = esm.pretrained.esm1b_t33_650M_UR50S()\n", - "esm1b = esm1b.eval().cuda()\n", - "esm1b_batch_converter = esm1b_alphabet.get_batch_converter()" - ] - }, - { - "cell_type": "code", - "execution_count": 6, - "metadata": {}, - "outputs": [], - "source": [ - "esm1b_data = [\n", - " read_sequence(\"1a3a_1_A.a3m\"),\n", - " read_sequence(\"5ahw_1_A.a3m\"),\n", - " read_sequence(\"1xcr_1_A.a3m\"),\n", - "]" - ] - }, - { - "cell_type": "code", - "execution_count": 7, - "metadata": {}, - "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "torch.Size([3, 315]) torch.int64\n" - ] - } - ], - "source": [ - "esm1b_batch_labels, esm1b_batch_strs, esm1b_batch_tokens = esm1b_batch_converter(esm1b_data)\n", - "esm1b_batch_tokens = esm1b_batch_tokens.cuda()\n", - "print(esm1b_batch_tokens.size(), esm1b_batch_tokens.dtype) # Should be a 2D tensor with dtype torch.int64." - ] - }, - { - "cell_type": "code", - "execution_count": 8, - "metadata": {}, - "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "CPU times: user 377 ms, sys: 117 ms, total: 494 ms\n", - "Wall time: 508 ms\n" - ] - } - ], - "source": [ - "# %%time\n", - "esm1b_contacts = esm1b.predict_contacts(esm1b_batch_tokens).cpu()" - ] - }, - { - "cell_type": "code", - "execution_count": 9, - "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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\n", - "text/plain": [ - "
" - ] - }, - "metadata": { - "needs_background": "light" - }, - "output_type": "display_data" - } - ], - "source": [ - "fig, axes = plt.subplots(figsize=(18, 6), ncols=3)\n", - "for ax, contact, sequence in zip(axes, esm1b_contacts, esm1b_batch_strs):\n", - " seqlen = len(sequence)\n", - " ax.imshow(contact[:seqlen, :seqlen], cmap=\"Blues\")\n", - "plt.show()" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## Run MSA Transformer Contact Prediction\n", - "\n", - "The MSAs used here are samples from the [`trRosetta` (v1) dataset](https://yanglab.nankai.edu.cn/trRosetta/benchmark/), also used in the MSA Transformer paper." - ] - }, - { - "cell_type": "code", - "execution_count": 10, - "metadata": {}, - "outputs": [], - "source": [ - "msa_transformer, msa_alphabet = esm.pretrained.esm_msa1b_t12_100M_UR50S()\n", - "msa_transformer = msa_transformer.eval().cuda()\n", - "msa_batch_converter = msa_alphabet.get_batch_converter()" - ] - }, - { - "cell_type": "code", - "execution_count": 11, - "metadata": {}, - "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "torch.Size([3, 64, 314]) torch.int64\n" - ] - } - ], - "source": [ - "msa_data = [\n", - " read_msa(\"1a3a_1_A.a3m\", 64),\n", - " read_msa(\"5ahw_1_A.a3m\", 64),\n", - " read_msa(\"1xcr_1_A.a3m\", 64),\n", - "]\n", - "msa_batch_labels, msa_batch_strs, msa_batch_tokens = msa_batch_converter(msa_data)\n", - "msa_batch_tokens = msa_batch_tokens.cuda()\n", - "print(msa_batch_tokens.size(), msa_batch_tokens.dtype) # Should be a 3D tensor with dtype torch.int64." - ] - }, - { - "cell_type": "code", - "execution_count": 12, - "metadata": {}, - "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "CPU times: user 8.54 s, sys: 561 ms, total: 9.1 s\n", - "Wall time: 2.3 s\n" - ] - } - ], - "source": [ - "# %%time\n", - "msa_contacts = msa_transformer.predict_contacts(msa_batch_tokens).cpu()" - ] - }, - { - "cell_type": "code", - "execution_count": 13, - "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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\n", - "text/plain": [ - "
" - ] - }, - "metadata": { - "needs_background": "light" - }, - "output_type": "display_data" - } - ], - "source": [ - "fig, axes = plt.subplots(figsize=(18, 6), ncols=3)\n", - "for ax, contact, msa in zip(axes, msa_contacts, msa_batch_strs):\n", - " seqlen = len(msa[0])\n", - " ax.imshow(contact[:seqlen, :seqlen], cmap=\"Blues\")\n", - "plt.show()" - ] - } - ], - "metadata": { - "kernelspec": { - "display_name": "Python 3", - "language": "python", - "name": "python3" - }, - "language_info": { - "codemirror_mode": { - "name": "ipython", - "version": 3 - }, - "file_extension": ".py", - "mimetype": "text/x-python", - "name": "python", - "nbconvert_exporter": "python", - "pygments_lexer": "ipython3", - "version": "3.8.5" - } - }, - "nbformat": 4, - "nbformat_minor": 4 -} diff --git a/esm/examples/esm_structural_dataset.ipynb b/esm/examples/esm_structural_dataset.ipynb deleted file mode 100644 index aa3ec94..0000000 --- a/esm/examples/esm_structural_dataset.ipynb +++ /dev/null @@ -1,332 +0,0 @@ -{ - "cells": [ - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "# Structural Split Dataset\n", - "\n", - "This shows how to load the structural holdout datasets described in Insert Section of our paper\n", - "\n", - "There are two tar files you will need. **The `StructureDataset` class will download these for you.**\n", - "- [The data splits](https://dl.fbaipublicfiles.com/fair-esm/structural-data/splits.tar.gz)\n", - "- [The pickle files containing sequence data, secondary structure labels, distance maps, and 3d coordinates](https://dl.fbaipublicfiles.com/fair-esm/structural-data/pkl.tar.gz)\n" - ] - }, - { - "cell_type": "code", - "execution_count": 1, - "metadata": {}, - "outputs": [], - "source": [ - "import sys\n", - "PATH_TO_REPO = \"../\"\n", - "sys.path.append(PATH_TO_REPO)\n" - ] - }, - { - "cell_type": "code", - "execution_count": 2, - "metadata": {}, - "outputs": [], - "source": [ - "from pathlib import Path\n", - "import seaborn as sns\n", - "import matplotlib.pyplot as plt\n", - "import os\n", - "import torch\n", - "\n", - "import esm\n", - "from esm.data import ESMStructuralSplitDataset\n" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "# Loading the splits\n", - "\n", - "Given the same root path, `ESMStructuralSplitDataset` will download the dataset only the first time it is initialized. Any other time, it will check if the folder exists and exit early." - ] - }, - { - "cell_type": "code", - "execution_count": 3, - "metadata": {}, - "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n", - "Files already downloaded and verified\n" - ] - } - ], - "source": [ - "for split_level in ['family', 'superfamily', 'fold']:\n", - " for cv_partition in ['0', '1', '2', '3', '4']:\n", - " esm_structural_train = ESMStructuralSplitDataset(\n", - " split_level=split_level, \n", - " cv_partition=cv_partition, \n", - " split='train', \n", - " root_path = os.path.expanduser('~/.cache/torch/data/esm'),\n", - " download=True\n", - " )\n", - " esm_structural_valid = ESMStructuralSplitDataset(\n", - " split_level=split_level, \n", - " cv_partition=cv_partition, \n", - " split='valid', \n", - " root_path = os.path.expanduser('~/.cache/torch/data/esm'),\n", - " download=True\n", - " )" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "# Examine a single sample\n", - "\n", - "Each element is a dict with\n", - "- `seq` : string\n", - "- `ssp` : string\n", - "- `dist` : np.array\n", - "- `coords` : np.array" - ] - }, - { - "cell_type": "code", - "execution_count": 4, - "metadata": {}, - "outputs": [ - { - "name": "stdout", - "output_type": "stream", - "text": [ - "Files already downloaded and verified\n", - "dict_keys(['seq', 'ssp', 'dist', 'coords'])\n", - "\n", - "sequence MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG\n", - "\n", - "SSP labels XHHHHHHHHHHHHHHHHH-SS-B-HHHHHHHHTS-HHHHHHHHHHHHHHT---EEETTEEE--TT\n" - ] - } - ], - "source": [ - "esm_structural_train = ESMStructuralSplitDataset(\n", - " split_level='superfamily', \n", - " cv_partition='4', \n", - " split='train', \n", - " root_path = os.path.expanduser('~/.cache/torch/data/esm'),\n", - " download=True\n", - ")\n", - "ele = esm_structural_train[0]\n", - "print(ele.keys()) \n", - "print()\n", - "print('sequence', ele['seq'])\n", - "print()\n", - "print('SSP labels', ele['ssp'])\n" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## Visualize 3d Coordinates" - ] - }, - { - "cell_type": "code", - "execution_count": 5, - "metadata": {}, - "outputs": [], - "source": [ - "coords = ele['coords']\n", - "xs = coords[:,0]\n", - "ys = coords[:,1]\n", - "zs = coords[:,2]" - ] - }, - { - "cell_type": "code", - "execution_count": 6, - "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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\n", - "text/plain": [ - "
" - ] - }, - "metadata": { - "needs_background": "light" - }, - "output_type": "display_data" - } - ], - "source": [ - "fig = plt.figure(figsize=(10,10))\n", - "ax = fig.add_subplot(111, projection='3d')\n", - "ax.set_title('3D coordinates of $C_{b}$ backbone structure')\n", - "N = ele['coords'].shape[0]\n", - "\n", - "for i in range(ele['coords'].shape[0] - 1):\n", - " ax.plot(\n", - " xs[i:i+2], ys[i:i+2], zs[i:i+2], \n", - " color=plt.cm.viridis(i/N),\n", - " marker='o'\n", - " )" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## Visualize Distance + Contact Map" - ] - }, - { - "cell_type": "code", - "execution_count": 7, - "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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\n", - "text/plain": [ - "
" - ] - }, - "metadata": { - "needs_background": "light" - }, - "output_type": "display_data" - } - ], - "source": [ - "fig, ax = plt.subplots(1, 2, figsize=(20, 9))\n", - "sns.heatmap(ele['dist'], ax=ax[0])\n", - "sns.heatmap(ele['dist'] < 8, ax=ax[1])\n", - "ax[0].set_title('Distance Map')\n", - "ax[1].set_title('Contact Map')\n", - "plt.show()" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## ESM-1b unsupervised self-attention map contact predictions" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "Note, this matches the `Quickstart` code in the README.\n", - "\n", - "The contact prediction comes from a sparse linear combination of the self-attention maps, trained with logistic regression on a few proteins, as described in our paper \"Transformer protein language models are unsupervised structure learners\"." - ] - }, - { - "cell_type": "code", - "execution_count": 8, - "metadata": {}, - "outputs": [ - { - "data": { - "image/png": "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\n", - "text/plain": [ - "
" - ] - }, - "metadata": { - "needs_background": "light" - }, - "output_type": "display_data" - }, - { - "data": { - "image/png": "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\n", - "text/plain": [ - "
" - ] - }, - "metadata": { - "needs_background": "light" - }, - "output_type": "display_data" - } - ], - "source": [ - "model, alphabet = esm.pretrained.esm1b_t33_650M_UR50S()\n", - "batch_converter = alphabet.get_batch_converter()\n", - "data = [(i, esm_structural_train[i]['seq']) for i in [0,1]]\n", - "batch_labels, batch_strs, batch_tokens = batch_converter(data)\n", - "with torch.no_grad():\n", - " results = model(batch_tokens, repr_layers=[33], return_contacts=True)\n", - "for (_, seq), attention_contacts in zip(data, results[\"contacts\"]):\n", - " plt.matshow(attention_contacts[: len(seq), : len(seq)])\n", - " plt.title(seq)" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [] - } - ], - "metadata": { - "kernelspec": { - "display_name": "Python 3", - "language": "python", - "name": "python3" - }, - "language_info": { - "codemirror_mode": { - "name": "ipython", - "version": 3 - }, - "file_extension": ".py", - "mimetype": "text/x-python", - "name": "python", - "nbconvert_exporter": "python", - "pygments_lexer": "ipython3", - "version": "3.7.9" - } - }, - "nbformat": 4, - "nbformat_minor": 4 -} diff --git a/esm/examples/few_proteins.fasta b/esm/examples/few_proteins.fasta deleted file mode 100644 index e9be9f5..0000000 --- a/esm/examples/few_proteins.fasta +++ /dev/null @@ -1,6 +0,0 @@ ->UniRef50_UPI0003108055 -MPADAREYLESKHATRRFDRPAEVAGVVAFLLSDDTSFVIGAGYLVDGGYTALRAARGRLGPRRQAAPAVKLLPNTDSPR ->UniRef50_A0A223SCH7 -MGPPRWWKGITGLAAVVHRADPEDKADLYAKMGLYLEYHPETRIVEARIKPRLHDVCESKVSEGGLEPPCP ->UniRef50_A0A090SUK6 -MKTPEDRVFRATDEYSDFVMACRYKGNEREFVIASHDKLNEAQVETLTSYLSGEWFKKTYITGIMNDSDGVLSQHEEYGDEVFCQPLDELRVDRYIMMV diff --git a/esm/examples/hhblits_uniclust_2017_10_1a3a_1_A.a3m b/esm/examples/hhblits_uniclust_2017_10_1a3a_1_A.a3m deleted file mode 100644 index 324bb4e..0000000 --- a/esm/examples/hhblits_uniclust_2017_10_1a3a_1_A.a3m +++ /dev/null @@ -1,2606 +0,0 @@ ->1a3a_1_A -LFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLAGRK ->tr|E6MGJ6|E6MGJ6_9FIRM PTS system, mannitol-specific IIC component OS=Pseudoramibacter alactolyticus ATCC 23263 GN=mtlA PE=4 SV=1 ----LIKKNIRLNRSPQTKEAIIRDIGKVFYDGGYTTEKYTEAMLEKEKVFNTAIGNNLAIPHGIEGMTGEILNSGLVIFSYPDGVDWGDG--QSVKLVIGIASVGDEHVDKLAKIAAACNTEEAVNKILAM-DVDDVYDLFK--- ->tr|D4YFK9|D4YFK9_9LACT PTS system, mannitol-specific IIC component OS=Aerococcus viridans ATCC 11563 = CCUG 4311 GN=mtlA PE=4 SV=1 ----I--Q-VPFHED---------------------------------KPSASVMAASNL----RNELKKAGSDLVAEAVPFAQLQNNS-----QTLIIVDADTVHPA---------KEVAPEAQFEEVSKLYEQNQYNKLLN--- ->tr|A0A0R2GJW7|A0A0R2GJW7_9LACO PTS system, mannitol-specific IIBC component OS=Lactobacillus acetotolerans DSM 20749 = JCM 3825 GN=FC77_GL000644 PE=4 SV=1 ----VKEVNFIRHDE---------------------------------HLGSATMATSLF----SDAMKKAGKKTPVKAVKINELDDDP-S--H--LVIVTPAAKKNL---------KLRYADIQIITVDDLLQDKKLKQIVD--- ->tr|A0A0N1CMM5|A0A0N1CMM5_9ENTE PTS sugar transporter OS=Enterococcus sp. RIT-PI-f GN=AEQ18_02700 PE=4 SV=1 ----IYIASEELAKTVDAKGAALFAVNDMLQMEQYRQLLTEGADYVLNQTRNDFIN------------------------------------------------------------------------------------------ ->tr|A0A1W7R1T6|A0A1W7R1T6_STRMG PTS system mannitol-specific EIICB component OS=Streptococcus mutans GN=mtlA PE=4 SV=1 ----IDAV-VFAHGI---------------------------------AKGSATMGQETL----RSIFKQNNVKIPVSTASYAHLSDYN-A--KNILLVTTIAQQGQA---------QQAAPNAQILVVDSLVTTPEYDKLVA--- ->tr|A0A223NA51|A0A223NA51_ENTFL PTS mannitol transporter subunit IICBA OS=Enterococcus faecalis GN=ADH73_12195 PE=4 SV=1 ----VNEI-LLVHDD---------------------------------RVGSATMGMKVL----EEILDKEKISMPIRKININELTQQT-Q----ALIVTKAELTEQA---------RKKAPKATHLSVKSMVNPQKYETVVS--- ->tr|H3K7Z9|H3K7Z9_9FIRM PTS system, fructose subfamily, IIA component OS=Megamonas funiformis YIT 11815 GN=HMPREF9454_01372 PE=4 SV=1 ----LIKDNILLNLSVSSKLDAFKELSSKLLINNCINdqKEYINALIKREQEFSTNIGFGIAIPHAKDK---SVNKASIAIGTFSPGLNYEDGEapVKLMFLLAVPTESDNLHLEILKRLSRKIIDTKFRENLLSAKTVNDIFKIME--- ->tr|A0A142B976|A0A142B976_9GAMM Fructose PTS diphosphoryl transfer protein OS=Endozoicomonas montiporae CL-33 GN=fruB PE=4 SV=1 ----LLKSHIFLQQFAPSKYQALKLACLKLVEAGMVCPGYFHGMCRRELLSSTYLDNGIAVPHSVPDt-RSEINYSGMIIIQFPRGVNWGNND--RTFLLCALAARGKEHLQMLSHLACSLDDTDLCRKLAVTEEVEHIYQSVT--- ->tr|A0A1C6GBT2|A0A1C6GBT2_9FIRM Pseudo-HPr OS=uncultured Eubacterium sp. GN=fruB PE=4 SV=1 ----LndeFQKHICLDFECTTIEEAIRKAGDLLVQCGCIKPPYIDGMIRREQEHSTHIGFGVMIPHGTEDTLDCVISPGISILKISNGVPYHGT---MITMVIGIASREEDPLQELMQITDILLTPEKCDQFLNASSKQEFIDMIN--- ->tr|R5ZC79|R5ZC79_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system OS=Lachnospiraceae bacterium CAG:25 GN=BN562_00059 PE=4 SV=1 ---NEFQKHICLDYECTTIEEAIHKAGDLLVQVGCVKPPYINGMIRREQETSTDIGLGVMIPHGTEDTLNFVLKPGISIVQIPHGVSYHGN---TIHLVIGISSREEDSLQELMQITDILLKPEKCHQFLNASSKQEFIDMINQ-- ->tr|S6G7V8|S6G7V8_9MOLU Phosphotransferase system PTS, mannitol-specific IIA component OS=Mycoplasma yeatsii 13926 GN=mtlF PE=4 SV=1 ---IKNKESVFLIDKFNSKIEAIEFVGNKMVELGYVDKQYIDSMIERDKTASVAIGNYLAIPHGNSDGFKYIKNSGILVVKLKEALTWDDEKV---NWIVALALEGDNQLEALQNLAIAFSEKSEVESMNKNlNTLDEIFDFFSN-- ->tr|A0A094P635|A0A094P635_9ACTN Uncharacterized protein OS=actinobacterium acMicro-4 GN=GM43_5035 PE=4 SV=1 ---LLQTAGIVLDATASSREEAVAVCGSLLRELGAIEPEYAEAMWEREQIFPSEIGGGFAIPHGTDKSRQYVLFDQLVFVRFLEPIAWVNE---QVSVAIGIAAAGDGHVEILGNLAEILLDDASAHVLLSSTSEEEIRSLLVK-- ->tr|A0A1B8W3N3|A0A1B8W3N3_9BACI PTS mannitol transporter subunit IIA OS=Bacillus sp. FJAT-26390 GN=A7975_20050 PE=4 SV=1 ---ILSTEKVKLNVSVKDKYEAIRMVGQMLVDAGHAPQAYIDKMIEREEALSTYIGGGLAMPHGTNDSKALIQSTGMAIIIVPAGVDFGGEE--PAQLVIGLAAVGDDHLDILTNVAVLVSEEEDMQRILNASSPQELISIFES-- ->tr|A0A1V8Z8C0|A0A1V8Z8C0_ENTGA PTS mannitol transporter subunit IIA OS=Enterococcus gallinarum GN=BH745_02185 PE=4 SV=1 ---DIPATHILLDQRFQSAEEALHEIGTFLVDQKMVQPQYINSLIQRHKKYGVYIGNFVALPHGEEEADKWINEEGICLVQVPDGVDFGDAKEsKVTTILFVVVLKE-KQLSCLQEIAFFCSDIQNIKLLSDAATIEEVQKILSL-- ->tr|A0A1Y4S5X7|A0A1Y4S5X7_9FIRM PTS mannitol transporter subunit IIA OS=Lachnoclostridium sp. An131 GN=B5E77_14105 PE=4 SV=1 ---VLTVNNIVLGADYPDRWEAIRACGEILFQQGYIRGEYIDDMMERERLFGVYMGNGIAIPHGVEGSERNILHSGISVLQLKRGVDFGTG---TAYLLFGIAGKDGEHIELLSRIAQVCMETEKVERMRITEDKEEMLQILNS-- ->tr|A0A1X1D3B0|A0A1X1D3B0_9GAMM Uncharacterized protein OS=Pantoea rwandensis GN=HA51_04045 PE=4 SV=1 --IKVTTDEITLGCKADSRAEALLIAANALINRGLVKPNFAQALLNREDETSTWVGGGVAMPHAARKNIDTVIETGYHFLQFPDGIKWER--GRVAFLVVVIAAKLNEHLDVLSGIAELLSDEMQASLLSSCKTEDEFISLLE--- ->tr|A0A0C5BG42|A0A0C5BG42_9MICO PTS mannitol transporter subunit IIA OS=Rathayibacter toxicus GN=VT73_03835 PE=4 SV=1 ----LTLGQIDPSGAATTKEAAIKEAADLLVRAEAVTSTYYQAMLAREATISTFMGNLLAIPHGTNDATREIRFSALSFVRYAQPIDWDG---HEVRFVMGIAGINNVHIEMLSKIALLFSENDEVQKLLDAPDAQTLYHLLSG-- ->tr|A0A1G4VK15|A0A1G4VK15_9MICO PTS system, mannitol-specific IIA component OS=Candidatus Aquiluna sp. UB-MaderosW2red GN=SAMN05216534_0608 PE=4 SV=1 ----IQQAGIQLAAAASSSEEAVASCGQLLFELGAIETEYAAAMWEREQIFSSAIGMGFAIPHGTDESRKFVNFDQLVFLRLENPIMWGD---EEVYCVLGIASQGDAHVDILGNLAELIQDPAHLATLMNSNSPSEILDLLLS-- ->tr|F7NGX7|F7NGX7_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Acetonema longum DSM 6540 GN=ALO_06593 PE=4 SV=1 -----ERNLIFIKTDFRDKTAVVEFLGGQLVQAGAVQPAYVQAMHQREQDVGTYITEGVAIPHGTEGSRSLVNRAAIVALKIPRGIEWSDG--KPVFLAFGIAGNEEDHVSLLSELAIMLMDADQKAKLLAAENEDDLFACLNQ-- ->tr|A0A1H3FJJ8|A0A1H3FJJ8_9FIRM PTS system, mannitol-specific IIA component OS=Lachnobacterium bovis DSM 14045 GN=SAMN02910414_00255 PE=4 SV=1 -----KKEMIFLDLDLKNKEEVIRFLGNKLYEQGNITKDYVESMIKREQEMSTYLKNGIALPHGIMSEsLEGIYENGVALAVINNEIEWDQG--NTVKIVLAIAADRITHMDILAKIAKIASDNEKINKLLTMSEDEIVLNFNK--- ->tr|A0A0K5Q8U8|A0A0K5Q8U8_ECOLX Putative DNA-binding protein OS=Escherichia coli GN=ERS085365_00947 PE=4 SV=1 -MKTFPLQSLTIIEAQQKQFALVDSI-------------------CRHFPGSEFLTGGdLGLTPGLNQPRVTQRVEQV--------------------------------------------------------------------- ->tr|A0A0B8Q9X2|A0A0B8Q9X2_9VIBR Fructose-specific phosphocarrier protein OS=Vibrio sp. JCM 19236 GN=JCM19236_1408 PE=4 SV=1 -MAE------------CKKFE------SNIRVAN-------------------LDGDGKV-----VNAKSLMKVIALGVKHGHQLqftAEGS--DAAEALASIGKAIESGLGEG----------------------------------- ->tr|A0A1B9JXI1|A0A1B9JXI1_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G12_11915 PE=4 SV=1 --LTINRSNYYLNCKAENKKDALRIISDEFIKSKNVTTDCFYALSKRENQISTYISNGVAIPHLSKDDRTIILKSDIKVFQFPQGVMWGES--HIVFITIAVLSKNdNDHIDTLKALTPLIKNDVAIDILSVTKHVDDFDKILSR-- ->tr|F5SXT3|F5SXT3_9GAMM Phosphoenolpyruvate-protein phosphotransferase of PTS system OS=Methylophaga aminisulfidivorans MP GN=MAMP_02307 PE=3 SV=1 --ELDLVQIVQLNVSATDKETVIEQATQLLVENNCVDPAFAQSMKQRETRANTFLGRGISIPHGIAEDRHLIKKDAVAILQIPQGVEWNP-G-QIAYMVVAIAAQTDGHITLLQTLTGLLQNDEQLQQLFKTDDEQLIVTSLNNS- ->tr|A0A1B8PXI6|A0A1B8PXI6_MORLA Phosphoenolpyruvate--protein phosphotransferase OS=Moraxella lacunata GN=A9309_09305 PE=3 SV=1 --LNLTATDVRMNAQATNKDEALSLLAKILSEDGLATADYLAGLQAREAQTSTYLGQGIAIPHGTPESRACVQQTGVRLVHFADGVVWNDDG-ERAYLLVGICAKSDEHLSILRQLTRTLGD-DVADDIKNAKTAEQIITIINGD- ->tr|A0A1C0BVU3|A0A1C0BVU3_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_02000 PE=4 SV=1 ----LNKDCIEVNCKKVERRQAIDDIGQTLLEAGFIEEPYIDGMHKRDESLTTFIGNDIAIPHGEYEVKPFVKQTGLAVKVYPEAIDWNG---NPVRVVIGIAAKDSDHLDILSNIAVKLGEMDVVEELVNSHDVDLIHRTLTRE- ->tr|A0A0M4M4K3|A0A0M4M4K3_9RHIZ Phosphoenolpyruvate-protein phosphotransferase of PTS system OS=Bartonella ancashensis GN=PU02_0003 PE=3 SV=1 --DILSLKSIQLSAVFSHKNDAIYAAVKLLMGSDVIKQHHLGGIIGsklITNVASIWFRSGVAVIYGITESYQLVMRDAVSVVQIPAGVEWQDER--RVYLVIAVITCADLHIKILKKIAPILFDEQKLKELSVIEDKQKIITALLG-- ->tr|A0A090RPD6|A0A090RPD6_9VIBR Fructose-specific phosphocarrier protein HPr /PTS systemfructose-specific IIA component OS=Vibrio maritimus GN=JCM19235_5680 PE -MLQLDTNTITLNQSSDNKLNAIKAIAADLTSKGLVQDGYVDGMLNREGQNSTFLGNGIAIPHGTTDTRDLVKQTGVAVHHFPNGVDWGDG--NVAYVAIGIAAKSDEHLGILKQLTKILSADGVEQKLKQAKSEKDIIALLNGDV ->tr|W1KAF3|W1KAF3_9ENTE PTS system ascorbate-specific transporter subunit IIA OS=Enterococcus durans IPLA 655 GN=H318_02540 PE=4 SV=1 ----VDKSLIQIDVEAENFEDAVRKSMEPLVAQKYVKPSYVEKILSIYRETGPYIviTTHIALPHADSE--AGALKMGMGFTKLKHPVISGNVANDPVKYLFPLSATDsTKHIQMLSKLAELLGDPSFVEGLDTVTSKEEFIALLTK-- ->tr|C4FP02|C4FP02_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Veillonella dispar ATCC 17748 GN=VEIDISOL_00624 PE=4 S ----LSEDNVSFHYPAETWEEVIRHGGQLMVDAGFTDPSYTEAMVEVVREMGPYIvlAPGLAMPHARPE--NGAKRVGTALVTLEKPLNFGSPDNDPVSVALFLCAPNkDEHIQLLTDIATLFEDDEFLDAAADFESIEDVQAFLAE-- ->tr|A5KJK6|A5KJK6_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Ruminococcus torques ATCC 27756 GN=RUMTOR_00404 PE=4 S ----LTEEMVRLDPPlLSTPEEVIEYCGNILVENKKAKAGYVKEMIDSYQRFGPYMvmAPGLALPHARPG--GNVKEPCISFVKLKEPVCFHHPCNDPVWVVFALGGVSdDGHIELLQDLSSLLAGERMIEKLAALNTYEELEKLMEK-- ->tr|L0K9H6|L0K9H6_HALHC Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Halobacteroides halobius (strain ATCC 35273 / D ----LNSKNIKTSVEVNDWEEAVEISGSMLVDNGLVKPSYIESMKDMIKKEGAYVviSPGLAIPHARPE--KGVLEPGISLITLKTPVEFGHSKNDPVKVVIAFCASDdSSHVEMMRELVTFLNANKNLQYLKEANNKDKLISYIQN-- ->tr|N1ZVP7|N1ZVP7_9LACO Uncharacterized protein OS=Lactobacillus murinus ASF361 GN=C822_01617 PE=4 SV=1 ----YDNNLVAISKKtPKDWEEAIRLSGEILKQNELITDQYVDQVINDVKEYGPYIviVPGVAMPHSSAKN-EGVLGTGIGFTLLPEAVSFEagNP-EKDAQLFFMLAAKDsAAHMENIANLSDLLMTEGLIADLKKVKTMEDYITVMEK-- ->tr|R7GA98|R7GA98_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Eubacterium dolichum CAG:375 GN=BN631_00349 PE=4 SV=1 ----LTQESVQYIE-cVESWKEAVVICVQPLIDQGKVDCEYISAVNRNIERYGSNFviYPYIILPHARPE--QGVKENAVSILLTKTPFHFDDN-KTPVRLVIVMAPMDsKSHLQILKEISGMLYDRNSIQSIMESKSKGQLYQRIRE-- ->tr|E1QXS4|E1QXS4_OLSUV Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Olsenella uli (strain ATCC 49627 / DSM 7084 / CIP 109912 / JCM 12494 ----LKRENVQVVETCGGWEDAIAVAVQPLVDGGYVTPAYVEGIIENTHKFGPYFvlAPDLALLHARPE--QGVISQQLAVTVLREGVEFKEG--EPVRVLVTLAAENpDSHIDVMRVLATMFSDPKNIEKVATASTADDIFGFFVS-- ->tr|G5IBC0|G5IBC0_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_00842 PE=4 SV=1 ----IFRDIRVCGEHFPDWKAVVDYVGETFVAKGYAKREYFEYIKKDMVENEAYMviVPHFALLHSAPE--HGALENVFHFMKLEHPVEFGHESNDPVAYVITFTSVDaDSHIAGISLLAGMLMKEGFVEELSRAGSDESLAACIRK-- ->tr|A0A174SCY9|A0A174SCY9_9FIRM Putative PTS system L-ascorbate family, IIA component OS=Flavonifractor plautii GN=ulaC PE=4 SV=1 ----ITDQSYL-EDVvCADWEELVEIGGGLLVKQGSVEPRFIQSIKDTIAEFGAYMvlVDDIAFFHGRPE--AGVKETSMSLALLRNPVYLS---EKRIKAAFTFAAVDkSSHLELMRELGGYLQDESFMDLLRNHGGKTAIMERLHK-- ->tr|Q8EVW1|Q8EVW1_MYCPE PTS system enzyme IIA component OS=Mycoplasma penetrans (strain HF-2) GN=MYPE4480 PE=4 SV=1 ----MTSNDLIAFHKgNISWQESIRLAVSLLVKNNIAESGLADEIIKSTLKYGPYYviAEKVALAHTAVC--EYNKKPGMSLVIFENAIKFSeNQ-KHEVNLLFCMSAIDsDSHMGILQKFANTLSQKDIVSKILNESDKTKIYEIFKG-- ->tr|B2Q496|B2Q496_PROST Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Providencia stuartii ATCC 25827 GN=PROSTU_01970 PE=4 S ----DDAKWIQINQVAADWKEALSIACTPLIIHGAAEPNYLQGIIKNTQSWGPYYliAPGIAMPHARPE--QGAIYNQITLTTLKQPVVFGHEDCDPVWLLMTVCATQsDDHIRLIQYIAELIDNPLLLDEIRCAKTHDDVLRLLNS-- ->tr|A0A1H1N4F5|A0A1H1N4F5_9ACTN PTS system IIA component, L-Asc family OS=Olsenella umbonata GN=SAMN04489857_1689 PE=4 SV=1 ----LKVENIQILDSVQDWREGVRVSLDPLVKGGYAEQRYADNVVKDIESVGPYVvlTDDIALIHARPE--EGAIKTQMGLLLLRKPVQFEGSD-SCVTLLFALSAEDpNSHVDAIKVLATFCMDESKVARLKESETPEEIYHLLIA-- ->tr|S5ZEX4|S5ZEX4_9CREN Uncharacterized protein OS=Thermofilum adornatus GN=N186_06725 PE=4 SV=1 ----AVEERIKVVEVVSDWKEAVILAGKLLQRDNCIEESYIEGMIKTCQELGPYIaiAPGLAIPHARPE--EGAQKTCFSILVVRKGVNFGS-HNDPVYIVVAFSSPDkKSHLKFLQVLAELFANKGEqiVNSLREAKNTYEALSILRE-- ->tr|A0A1W1YK31|A0A1W1YK31_9LACT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Aerococcus suis GN=SAMN04487984_0746 PE=4 SV=1 ----LDQMYIQIY-DsLPSWREALYLAGEPLLHANIISRHYLKQIEAAAEFLGPYMdvGRGIGFMHARPE--EN-ESWGISLLKLQEPVYLLdQT-NHPLKIVIVFKGKDaKQHLKILQVLSEWLANPLQYQFVCEATSPESIINSIKQ-- ->tr|A0A1Y0L1G2|A0A1Y0L1G2_9MOLU PTS ascorbate transporter subunit IIA OS=Spiroplasma clarkii GN=sgaA PE=4 SV=1 ----MDK-QFCKIINkTMSWAEAIKASAQTLLEENYFNENYVIEMIENVKKFGSYIviAPKIALPHASYS--KNVFKGGFSITIFPLGIDFQAS-SGPVYILVTISSTNnEEHLQRLKEISSKLSNQAVVTSLLEAQSSEIVWEKWNE-- ->tr|A0A1C6Z4I9|A0A1C6Z4I9_HAFAL PTS system, mannitol-specific IIA component/PTS system, ascorbate-specific IIA component OS=Hafnia alvei GN=BN1044_03651 PE=4 S ------ENAFHVVDSVDDWRHAIDIVTAPLTASHRIEARYCTAIKTATqELGPYYvLGAGVAMPHARPE--EGVIDTALSMVLVRGGVDFGT-GTEKVTILICLAAKDaDSHIYAIQALCEILSDGEVINEINNACDALALQEIIK--- ->tr|A0A0F4KYB4|A0A0F4KYB4_9LACO PTS Asc IIA OS=Lactobacillus mellis GN=JG29_00350 PE=4 SV=1 ----LSPKAIQFKVPVQNWQEALYVTSKPLLNMGIIKKSYIDRMIASVnQYGPYIvIAPGIALGHARPG--NDIRHTAIALATLDPAINFGNKINDPVDIVIILAASNnNDHLELLQKLVKFLNNSQNLAYLKSSSSDSDADCISRL-- ->tr|X5DVI6|X5DVI6_9CORY Putative PTS system, IIA component OS=Corynebacterium glyciniphilum AJ 3170 GN=CGLY_11135 PE=4 SV=1 ----VAEDHIVLRDAVQGWRDAIEIVGGILVDKGNATRDYVDAMIASIaGpNGTYIdLGAGIALAHARPE--NGVQSTGLSVLHLGEPVLLADDPTHPVTVFIALAAVDsRGHLDVMKNLARVLTDEDLRQTLLNATTSADIVSALSP-- ->tr|A0A0F0C3J8|A0A0F0C3J8_9CLOT Ascorbate-specific phosphotransferase enzyme IIA component OS=Clostridium sp. FS41 GN=ulaC PE=4 SV=1 ----VSLDDIELNVSAADWQDAVIKSGTILLNNGYVTREYVNAMVQTVkNLGPYIvVAPGLAMPHARST--NGVIKSGISIMTLSQPVEFGNESNDPVYLLIGLAGSNdDLHLKIMQAIATIFEDDRMLERITACDRREMVARIFND-- ->tr|A0A1N6Q7Y8|A0A1N6Q7Y8_9SPIO PTS system, ascorbate-specific IIA component OS=Spirochaeta americana GN=SAMN05920897_10448 PE=4 SV=1 ----IATRTIAVRQATSDWEAAVRLGGEMMKSAGLVEQSYIDAMVDNHkKIGPYYvLAPGIAMPHAKPE--EGVRKTGYAVVTLAQPVSFGDPENDPVDLLIFAGAISrEDHNEEVVPQVAELCDSESYvARLRGAPTVEAAISVLRD-- ->tr|A0A1R4FWA5|A0A1R4FWA5_9ACTO PTS system, mannitol-specific IIA component OS=Actinomycetales bacterium JB111 GN=CZ771_11535 PE=4 SV=1 ----IIDQGVMWNVSAESWQELTLGVGQRLIELGLCDERYPDAMVQNVvKNGPYLvIAPGLALLHARPD--EGATKNGLVMGTSANSIEFGHSTNDPVTLFIGLTATGdMEHLDMLQEVAQMLAAPGALDGLRSATSESDFVAKLRA-- ->tr|A0A1R4FDF3|A0A1R4FDF3_9MICO PTS system, IIA component OS=Agrococcus casei LMG 22410 GN=CZ674_04000 PE=4 SV=1 ----VATATYASGVYAPSWEEAVRAAGLDLVNAHAVGPAYIDEMLQIIdNYGPYCvVAPGVAVPHANAS--SLVRKDGVAVLALEEPVRFGHPHNDPVRLIVGIAATTaKRHITMLAGLAKSLDAPGVVNQIVAAGSRKEALELLGV-- ->tr|A0A1R4EW33|A0A1R4EW33_9MICO PTS system, IIA component OS=Gulosibacter sp. 10 GN=FM112_00320 PE=4 SV=1 ----FNTGMVRRGLPAAGWREAVTAAGDLLVDGRCVRRGYTEKLVDIIeRFGPYMvIAPGLALVHAQPS--ADSLQRGISAVTVPDGVDFGHSHYDPVSLVIGLSTTNaSEHLDIVAGIANDLEGSEGLvARAAAAESDEALVELVRA-- ->tr|S4ZXM2|S4ZXM2_LACCA PTS system, fructose-specific IIA component OS=Lactobacillus casei LOCK919 GN=LOCK919_2995 PE=4 SV=1 ----VIGNNINLASKAQTKDEALQELCHMLKQNGTVSdeRLFYQDVLKREKIGATGMENGIAIPHGESD---AANKVAIAVLKTRHALAWESLDDQPIRLVFLLVVpttgRDVLHLKLLSHLSAALTHREVQEKLLHENDADQFKKILE--- ->tr|E0P0N9|E0P0N9_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Selenomonas sp. oral taxon 149 str. 67H29BP GN=ptsN PE ----HENQIVFLEDSFSSKNEVIHHLTH--RENSAVRdaDQYERDVLEREASFATYTIDGVAMPHAKSE---GVSTPFVAFARLKTPVRWGTEEGEDARMVFLIGVpkvgstaDNNLHLKILAALSKKLIHDEFRAQLSTANSTKDIYALLQ--- ->tr|A0A1E9J214|A0A1E9J214_9FUSO PTS fructose transporter subunit IIB OS=Fusobacterium sp. HMSC073F01 GN=HMPREF2747_10990 PE=4 SV=1 ----INANRILLNKTMKNKNEAIKEMAKLFVEDGVVDnyDEYLKSLMDREAIAETAVGYEVGLPHGKST---AVKYPAVAFARLSKDIMWSEEEQETAKFIFMLAIptaaAGNEHINILVNLSKKILDDDFRELLSKSNDVEEIMNAIN--- ->tr|A0A1F8JTY3|A0A1F8JTY3_9BACT Uncharacterized protein OS=Chlamydiae bacterium RIFCSPLOWO2_01_FULL_28_7 GN=A2888_00675 PE=4 SV=1 ----MDVNNI-VFLTKKNRNDVISELIENLYKTQKIKnkNIFFDNIIKREKLFSTGIGMGVAIPHTKNG---DFENFFIAIGIQkKNKINWLSIDKIAVNIVFMIAGpenKQSEYLKILSKLTSLIKNESFKNKLLKFEFKEDIFAFFD--- ->tr|A0A1K2I8K0|A0A1K2I8K0_9LACO PTS system, fructose-specific IIA component OS=Lactobacillus rennini GN=LREN565_1816 PE=4 SV=1 ----FDLQNIFTDVTVTGNKNAALQKMAELFASKNQLdaKALLKGFEAREQESTTGFGSGVAIPHTKIA---GLKQPLVGMTTFTQPINWESLDEQPVTIAIALLMpiadSSKAHLSVLAKFARKLMDEQFVADLQAARHQAQSLyQVVT--- ->tr|A0A1L8P610|A0A1L8P610_9LACT Uncharacterized protein OS=Alkalibacterium sp. 20 GN=AX762_11660 PE=4 SV=1 ----ETKVILDLNNKYTDKKSFFAELCEVIHNEMDEKvlaITIKEALEEREKVVTTGFGNELAIPHGKVE---GLISPYLFFVRVKNPIEWQAMDDEKVKFIFVILVpsddKDNNHLKVLSILSYNLMDSEYQKMIKTVKDEEEAKNIIE--- ->tr|D8ID52|D8ID52_BRAP9 Putative PTS IIA-like nitrogen-regulatory protein, PtsN OS=Brachyspira pilosicoli (strain ATCC BAA-1826 / 95/1000) GN=ptsN PE=4 ------LDSVKIIDNTNNWQDAVEECFKPLLKKEYINKEYIQKVIDSGKELNFYylIGKHLAMPHAKRE--SGVFKNGITLLVVKNGVNFENHSNNPIYCLIGLAAVDnDSHIEIMSDILDIFGSEEDGVvanELRNMNSEeeii----NYlLNK-- ->tr|R6DK77|R6DK77_9CLOT Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Clostridium sp. CAG:242 GN=BN558_01795 PE=4 SV=1 ------KQSIACAVSAQNWEEASRQAAQILIDKGAIRSEYLTRMMEKLEKERSYmvLTSGVAVIHARPG--EDVCKNSISLLTLKQPVEFGNANYDPVSVVFMLAATDdNSHIRLMMAVAQKLSQPDIKEKMLAAKEIeelw----TLmQD--- ->tr|A0A0E3Z9F0|A0A0E3Z9F0_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_00290 PE=4 SV=1 ------KELINFNIQARNWEDALENTCNILEKNGYIEHKYINKLINITKEIGPYyiITSNVGIPHLRPD--EGVIKSGLAFFKLRNKVDFLG---NKIQYLIYILALNsNEHIDKIQSITSILEDKNLFESLNNNKFNiDEFIKYINN-- ->tr|A0A1B3SM11|A0A1B3SM11_9MOLU PTS system, ascorbate-specific IIA component OS=Spiroplasma helicoides GN=sgaA PE=4 SV=1 ------KENFLYVPEVKDWKELLKIGTSYLKEKNIVTNKYHEALLKEIDKLGFYfiISKEIALVHIAPG--GENLKTNLLFINLGKEINFSSDERHKVKHCFFLTAINsQDHIEILSNFAKEMSNKQFVKELDGVKDYenyl----SISKQ-- ->tr|A0A1W1X2C8|A0A1W1X2C8_9MOLU PTS system, ascorbate-specific IIA component OS=Mycoplasma agassizii GN=SAMN02745179_00613 PE=4 SV=1 ------KDLIKISDQKLNWIEAIKEGVGLLEKKKYCQMSYADSIIESTNKYGPYyvISPLLALAHALPE--GNVSKVGLSLVLYKNIVNFSDKNEHQVQLLFTLCTTSpNDHIEMLQKFVTvFNENKDLTNQIINATTVdeih----QLLKE-- ->tr|M5DZY0|M5DZY0_9FIRM Uncharacterized protein OS=Halanaerobium saccharolyticum subsp. saccharolyticum DSM 6643 GN=HSACCH_00965 PE=4 SV=1 ----LKQNQIKIIDEEIDWKEAIKQAGKLLLDKDLIEAKYIRRMIEIVEDKGPYiaIAPEICLAHAGIE--DGVNESAISLLVIRNGIKLGH-QFDPIKFIFVLAPINKKgHMPALTDIMDFANNSELMAKIAAAKSEAAAYKILE--- ->tr|S6EI85|S6EI85_9CLOT Putative PTS modulated transcriptional regulator,MtlR family OS=Clostridium chauvoei JF4335 GN=CCH01_001930 PE=4 SV=1 ----FSINNINLSIEESDWREAIRKSAKPLLEDGVINKAYIDDMVKNIEDLGPYivVDDGIAIPHAKPG--KNVKGFGFTITTFKEPISILN--KDGVKVFFTMATENEKdHIDIITQLMKLVEDEDFIELLKVSSNPVKVFQRVR--- ->tr|A0A1T4K7D6|A0A1T4K7D6_9FUSO Transcriptional antiterminator OS=Cetobacterium ceti GN=SAMN02745174_00370 PE=4 SV=1 ----LDKEGIYLNLEGMSWEESVRTAGEILLKRGSIKKEYISEMINKINIFGPYmvTDDKLALPHSKND--NTVKKTDMVLLTFKENIIF--PENTPVKTILAFSSVDGIeHLNALSQFMDLINNYRFLEKIKSGLDSKKIIDLIK--- ->tr|A0A1U6TNA6|A0A1U6TNA6_9MYCO Probable licABCH operon regulator OS=Mycobacterium abscessus subsp. abscessus GN=licR_4 PE=4 SV=1 ----WNKGTCLSESL-KYGLKVLKQQGSILNDKE-----VFAALEAR-------aEIGGLAIPETTLA--LYhtsnnqIEKPSFNIIDLPEMVSLRAmnGANEMVKRVLLLLAPLNAsseVMEVLSFLsASIIESERSIEVF-NKGNKEELLNFIS--- ->tr|A0A1W1XNX2|A0A1W1XNX2_9CLOT Transcriptional antiterminator, BglG family OS=Clostridium acidisoli DSM 12555 GN=SAMN02745134_02524 PE=4 SV=1 ----FFTEICATNVNGiiQELLEEQVKYGVIDMKT---SDGIKVMLVNR-------dKLGTIILPNKKFV--IYhcvssdIKEPMITVGKLKIPIKLINliDKKELIYTAFLMVAPLNKkdSLEVIGDLsSSIIEQVDFIDRLNESKNAEECRKIIE--- ->tr|A0A1Y4HN69|A0A1Y4HN69_9ACTN Uncharacterized protein OS=Collinsella sp. An2 GN=B5F33_04560 PE=4 SV=1 ----L-LGNVRLDKEAHSWQEAVRVSGEPLVESGAIDSGYIDLVVANITELGPYvvISQGVALPHAAGA--GHVHRTAMSCVRLAEPVAFGAADRDPVRFVFMLATVDATsHMRALVHLAELLTTPEFMQTLAETDNVQQLMDFVT--- ->tr|A0A1Q9HEQ3|A0A1Q9HEQ3_9VIBR Uncharacterized protein OS=Vibrio panuliri GN=BIY22_08585 PE=4 SV=1 ------GKRIKYSDVKLSWDDALEQSIAMLQHDGIVNQHYIEAIRSVTDEIGPYyiLTDDLAMPHARPdE--GVIAGqGGLSLLICHSPVRFDQ-EHSAVRAFIGLAAGdSEQHVLTISNLMNWLDSDDAMEKLLSVQNQSELERLVES-- ->tr|C4XFJ8|C4XFJ8_MYCFP Putative uncharacterized protein OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=MBIO_0655 PE= -----VNDSIVPHVDVKDWKDAIKKACLPLEKAKVINSKYYDCILESiKKHGPYFiLVDGLAMPHASAT-KDAVFGNGFSLITLKKPIKFEGDE-REVKILMGLAAKDgETHTSvAIPQIIAVFEDPQNIEKIAQAKTKEEIINIIKG-- ->tr|B0P4U7|B0P4U7_9CLOT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Clostridium sp. SS2/1 GN=CLOSS21_02803 PE=4 SV=1 -----DMICTRVIEEVKDYQSAIKMTCDILEEKGAVNHTYYQAILDNiEKYGGYFyLGKGICMPHART--EDGAIKSGMCVLMVKNKVRFFNNQ---VRVFITIAAKGeMEHFKNLHRIANFCNDEEKMKRLEEIKDEKELLELIGE-- ->tr|A0A1B7HJN4|A0A1B7HJN4_9ENTR PTS system ascorbate-specific IIA component OS=Buttiauxella noackiae ATCC 51607 GN=M979_3241 PE=4 SV=1 -----EAQAIQVGVRETDWKKVIRLAAQPLVDNGYILPSYYQAVINNtLEHGAYYvFEEGVAMPHARP--ECGVMKNCFSLVLLDEPIAFAD-S-EKADIVIMFAACDsNGHIEeGIRAIVNLLGDDDVMAKLRRAKGKEEVIAIL---- ->tr|A0A1C5W7K5|A0A1C5W7K5_9FIRM Mannitol-specific cryptic phosphotransferase enzyme IIA component OS=uncultured Eubacterium sp. GN=cmtB PE=4 SV=1 -----KKENIVLKRHAKDWKEAVHISLEKLVEGGYCTDQYEQGVLKNtAEYGPYYvLTEEFALVHCND--FASVNETQMAVTTLDEAIKFSEDG-YDVRILVALVAVDgDKHLDGIRAISNIFADEDKVQEIIDATEPEKVLQMFIE-- ->tr|A0A0Q4NI99|A0A0Q4NI99_9ENTR PTS fructose transporter subunit IIA OS=Erwinia sp. Leaf53 GN=ASF13_18005 PE=4 SV=1 -----ARENIFLNQAFTSKQEIFRFLAGHAVAQGWAEsaAAIEADLWQREQQYSTGFENQIAIPHAKTAN---VSQAGVIFIRLAQPIEWESLDDQPVQIIFGLLVPesgaKVLHLQIINSLASQIVEDDFRQFLFIAESENALFEFMKS-- ->tr|R2R040|R2R040_9ENTE PTS system, fructose subfamily, IIA component OS=Enterococcus raffinosus ATCC 49464 GN=UAK_02653 PE=4 SV=1 -----VNDLIVFDESIRSKKELFEKLGQLLEEEQRVSkaKKVIKDLYRREEETSTGIEDGFGIPHAKSKA---VLQPTICFAHTGKITDYVGLDGRNIEWVFAILVPqktAYIHLEILSKLSRKLMNESFRTQLKNAGSPMEVLEIMSK-- ->tr|H9ULG8|H9ULG8_SPIAZ Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Spirochaeta africana (strain ATCC 700263 / DSM -----DESLVRPGMTAENKDDVVDQMLQMLAATGKVGdvAAAREALIANEQRTATGMQHGIAIPHAKTEA---VDELLACVAVTTKPIDCSAVDGKPSRIFIMTLSPpdrvG-PHIRFLSEIGRILKSRKVRDRVLKAATPAELLQALGG-- ->tr|B1BZF5|B1BZF5_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=[Clostridium] spiroforme DSM 1552 GN=CLOSPI_00332 PE=4 -----DKECVVFDIPDTTKDNVIKTLISKLDKVGCISnvEEFYKNVLDREEICATAIGNEMGLPHGKTSN---VLRPSICFGRLLNPVIWNEKTGEKVKYVILIAVPeknsSDVHMKIISSLARKLMHTEYRNILLNGTQEEVFDFLNAT-- ->tr|A0A1G2ZJ68|A0A1G2ZJ68_9BACT Uncharacterized protein OS=Planctomycetes bacterium RBG_16_43_13 GN=A2W23_08870 PE=4 SV=1 -----SEKVILTNFKAGTKLDAVGRLVDVIIASGDIPkhhrQAVLDALIARENICSTGMEHGVAIPHATVDV---LERPAAAVAVSLEGVPFQSADGKNATIIVLLIITrkdvK-HNVRTLAGIARLLNYEDTRQHLLVAKTPSAILDVIRE-- ->tr|A0A1V5G8W5|A0A1V5G8W5_9BACT PTS system fructose-specific EIIABC component OS=candidate division BRC1 bacterium ADurb.BinA364 GN=fruA_1 PE=4 SV=1 -----IERAPLVELTAKTKEEALRQLAEAFRGEPKVAnlDRFIEAIFAREKVISTGIGIGVAVPHVKIPE---VSDFVLAFGRHREGLDFDSLDDQPVHLLAMIGASeaqaG-EFLKMLARLVRTFRARDVRRKLMQAENAEAFRAVLRE-- ->tr|A0A1V6GIS4|A0A1V6GIS4_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin070 GN=fruA_2 PE=4 SV=1 -----QKSLVCLNATESEGQEVITALIDKAVHAGLLPaehrDTAVRAVLNREMSASTALPDGIALPHGRIEC---VRDIICMLGVHPAGIAFGAPDNQPTHVFVLLLVPatvaC-NHIHFLAKLSRRLMEASVRNELLAARTRDDVMRTILS-- ->tr|D6XZQ2|D6XZQ2_BACIE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN ----LHESRIQWEQKAGDWKDAIKKSAAPLLNDGDINETYVEAMIRNiEELGPYIlIAPDVALPHARPE--HGVEKAGFTVTVFKEPVPFPKGTDQSvseARVFVCLAAVdSESHLGLLQQISGLIEDRSLIEALLQASSEADVHKALSG-- ->tr|A0A1C0ADK1|A0A1C0ADK1_9FIRM Transcriptional regulator OS=Orenia metallireducens GN=U472_00180 PE=4 SV=1 ----YLKGNINFLDEVSSWEESIKVAAKPLLKKGFITDKYIQSMIKNvYDNGPYMvIVPRIAMPHAQDK--EGVIKTGISFLKLKKPVLYPEGKEV--NISVVLAAEdNSGHLELIADLSSILADEEVRNKFENVESEEELIKIIKT-- ->tr|A0A1U7APA6|A0A1U7APA6_LISMN PTS sugar transporter subunit IIA OS=Listeria monocytogenes GN=BWI22_14415 PE=4 SV=1 ----LNKELVNLHGTAKNADEAIVQAGELLVNAGYVSEQYVEKMVESyHENGAYFvIAPQIAIPHARPT--DGVENSAVSLVVLKDGVNFGHAANDPVRLVFGLAATsSEAHLKVIQKIVSLLSNNDNIEKMIHSEDYQAIGELVEG-- ->tr|F5T9Y6|F5T9Y6_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Oribacterium sp. oral taxon 108 str. F0425 GN=HMPREF91 ---------YSFINGKDvSWQEAVRLSALPLVEDGSVDSDYYKQIVACIEKHGPYivMEHNIAMPHTTENP-IGAHRTAVGLMICENKIDFGqdTdGEKKEANLLFTLSAVNTdEHMENIAQLMDVFMNYDLIEALGKCHSAEEILEAMKK-- ->tr|G2IE46|G2IE46_9CLOT PTS system, IIA component OS=Candidatus Arthromitus sp. SFB-rat-Yit GN=RATSFB_0858 PE=4 SV=1 ---------YSFHESFDDWREAIKASYVPFLKNGIVNDFYVDAVIKSVEEYGPYivLMKDIAMPHSNVNE-DWCKETSIAFMKVKKPVIFDPnDSEKQARLFFSLSIRDNeEHIKNLQGLMEVLENEELVSELLEADNEQEFRKIVDK-- ->tr|C8NEQ4|C8NEQ4_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Granulicatella adiacens ATCC 49175 GN=HMPREF0444_0399 ---------FSFQKGSLSWEEAIKKACQPLLEQKIIEPEYPGYIISNVHEFGPYivIAPEICIPHAQEGK--GVNDTAVAFMNIEEAVDFGPGADYQPHLFFVLASTDNeKHLNNLSELVTLLDDESIINAFVEARSKEDLENILKG-- ->tr|A0A1Q6MWC4|A0A1Q6MWC4_9FIRM Uncharacterized protein OS=Clostridiales bacterium 42_27 GN=BHV90_19355 PE=4 SV=1 ---------FDVYSGF-dTWEEAVKTASSPLIRQGLVEPDYADSIIENVAENGPYifIAPHICMPHSKRT--DLVRQAAVSFVKINRPVCYDesD-PEMGAELFFAIAVKELnAHLDVMMDLADVFDDEETVRALLDAKTKEDFDKLLG--- ->tr|G7M9S6|G7M9S6_9CLOT Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Clostridium sp. DL-VIII GN=CDLVIII_4738 PE=4 SV=1 -----TINTVEFNLNLKTQGEVLEKITDILFKDNRIEdkKETLKGYIDRENECTTGIGFGLAIPHCKVE---SVIKPTIVCLKLNQAIDWNSLDEEPVNIIIGLAIPkkyeGTLHLEILGKLASNLMEDDFKRTLFNINDKNKLVTFLQE-- ->tr|I7KTP2|I7KTP2_9CLOT PTS system, fructose-specific IIA component OS=Caloramator australicus RC3 GN=CAAU_1104 PE=4 SV=1 -----NENLIVTGLEASNKEETIKKLIDMLEKEERLIsrEKFFEDVLFREQLCSTYVGQGVAIPHGKTD---AVKKTSVAIGKLAKPIEWDEKENNYVNIVFLLAVQdkdaDNQHLRILANIATKLMEKDFIDNLTSINDKDGILALFRE-- ->tr|E3DMB1|E3DMB1_HALPG Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Halanaerobium praevalens (strain ATCC 33744 / DSM 2228 / GSL) GN=Hpra -----SEDLINLDFNPVNKEDALSKMVQMFKKENKIKseTDFLNKIFKREKEGSTGFGRQIAVPHGKSK---TVKELSLAVARVKNGLKYNSLDGQKVKLIFMVADYegySPQYLKLVSTLVSLLRDNNFRTKLIEAKNKNEFIDLFRK-- ->tr|W6A8C9|W6A8C9_9MOLU PTS system fructose-specific IIA component OS=Spiroplasma culicicola AES-1 GN=fruB PE=4 SV=1 -----NINSIIIDTDFSTQEQVFSHLSKYFVKNSYCTnyEEIKVGFFEREKEGSTAFTDGIGIPHSKVN---SIIQPGIYVIKNKNGINWDSLDGKETNFFIALAIPnldsNTLHLKMLSSVARKLVDKEFKKNILNAKTKEEIFELLSL-- ->tr|A0A0R2LLZ1|A0A0R2LLZ1_9LACO Uncharacterized protein OS=Lactobacillus paucivorans GN=IV54_GL000510 PE=4 SV=1 -----NPNNISLHLECSDQEALLQKMTHWLFQSHAITneAGFLEDVDYREMLGMTGIGNEVAVPHGS-N---CVAYPTVAIATLQAPIAWKSIDDAPVRLVLLFAEPdeptpDQAHNTLLTKMIRKLSNDETLYAVKQAATVDEIVNALKE-- ->tr|R7PMI9|R7PMI9_9CLOT Uncharacterized protein OS=Clostridium clostridioforme CAG:511 GN=BN688_00912 PE=4 SV=1 -----NENAVAVNVKAQNKEEVFECVCDLLLKDGSITskEEFKQDLYIRESQGKTGIGDGIAIPHGKSL---AVKRNCISVLKLERPIQWETLDGRPAQMFIIFAINqrdkDDYFLRLMASVAKKLAQEGTCGKLMGSSTKEDILEAFY--- ->tr|A0A1R1LCC1|A0A1R1LCC1_9MICC Uncharacterized protein OS=Tersicoccus phoenicis GN=BKD30_06445 PE=4 SV=1 -----NPRMVRVGLPGQTKAEVFRSMATLFVETGKVTdlERFVEDLQTRERSISTGVGRGLAIPHGKSE---AVSTATYAIATLRDPFLWDEDDEETTKLVVMLGVPanepATTHLRLLSEFATALMDDEFRAELINAEDEADIRSALAS-- ->tr|A0A1I5TU97|A0A1I5TU97_9GAMM PTS system, fructose-specific IIA component OS=Enterovibrio norvegicus DSM 15893 GN=SAMN03084138_03341 PE=4 SV=1 -----NVEHILTDAHSTSQQQAFQFIAEHAHQLGYIDsvDGFARGLQAREAHDSTGFLGGMAVPHCKSA---HVKTPAIFVVHFANPIEWDTMDDEPVTTAVSLAIPesgAEESLMMLTKLSRAMMKPDIRNTLQQNDTQAILDTIQHV-- ->tr|A0A069ADX8|A0A069ADX8_CLODI EIIBCA-Man OS=Clostridioides difficile GN=manP_6 PE=4 SV=1 -----TEESIILDLKSTTKEGIIQELVDKLYDTGSITlkSKFIKALKHREKIGSTSIGYQMAMPHGKTK---YVKKASVVIGKSKKGVDWPSIDGLPVKVIIMFAMPqsgGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYE-- ->tr|A0A1V3NT24|A0A1V3NT24_ENTCA PTS sugar transporter OS=Enterococcus casseliflavus GN=BZK37_00465 PE=4 SV=1 -----TPDLILLNSDLADQDEVIRHIVEAAEFVGYVEdaDELYQAVRKRESEVPTAIGYDIAIPHGKTE---AVLHPFIAFLRVNKAFQWTKENEEMVRLVFLIGVPqnseGKMHLKFISQLSKKLLDDDFRDKLLSETDKNKIYEQLSS-- ->tr|A0A1W9VGW4|A0A1W9VGW4_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_59 GN=B6241_00715 PE=4 SV=1 -----KKEC-CFRLNENKKTEVLIEMMECIHQKGFIEdlENLKKEIFYREQLMSTGVGMGIGIPHVRFK---GVEKPLIAIGIKeKGVVDYDSIDNEDIKIIVMIMVGenqHKEHIRLLSQVIGRMKDAGDREKLIHASDSEEIYNLLTG-- ->tr|A0A123T4K4|A0A123T4K4_STRSU Putative PTS system, fructose-specific IIA component OS=Streptococcus suis GN=manP PE=4 SV=1 -----TLQQIFFQ-HFLEKEEVL---SEIAILAEKLGiasGNIYDELKKREEEYSTAIGHGLAIPHAKTDL---IHSPAILFFKLEQVIDWSGDEV---CMIIAILTPrseAGIHLSILSRLSRKLMHREFRERLEAAQTQQEVFDLFR--- ->tr|A0A1F7RL77|A0A1F7RL77_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium GWA2_38_11 GN=A2042_03675 PE=4 SV=1 -----LFEDQVYLDLK--AKNSFGCFLEmlrCLEDSKIIKdkAPILTALMTREELEPTSVGCNIAFPHARTFQ---LEKPILIIGRSKEGIDFYSRDGKKINFVFMLLFPrkfNELYLELVGEIMRFLSNSALLDCLQKINTPEELITLIK--- ->tr|A0A1C6HDE7|A0A1C6HDE7_9CLOT EIIABC-Fru OS=uncultured Clostridium sp. GN=fruA PE=4 SV=1 -----DENTVNLELEANDRDSVIRELAKMLNHNGLIQdlECFIQSVLEREKICSTYSTSELAVPHGISPS---VRKAGLCFGRLTSAIDWDGDQETPVRYVFLIAIPqaedeavINRHLEMISSIAVSALqednlekwgkvkdAEEFLATLETADGRG---------- ->tr|A0A1C0BWB0|A0A1C0BWB0_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_08765 PE=4 SV=1 -----NNQTVFLNVEGSTKEAILQAVTQQLETSGYVKnaKHAYNDIMKREAEISTGFVSGIAIPHTQSEA---VEKTSISIIKPVNSLSWETMDDSDVDLIFLICVPlngLDEHLKILASLAEMLMDEDVIDALHQIENEDEIVDYIR--- ->tr|A0A1F5RLG1|A0A1F5RLG1_9BACT Uncharacterized protein OS=Candidatus Eisenbacteria bacterium RBG_16_71_46 GN=A2W00_06915 PE=4 SV=1 -----DPSLFVPDLRTRRKESVLGEMIARA-HlAGAVRlpELLRETLVLRERAGSTAVGKGVAVPHARSLS---VSEPHLVVARSRRGLAWTPGDPQPVTLVLLALSPaevPAEGHLDFVARVVGATrlQR-NRQKLLEAESFDAVAAVLR--- ->tr|A0A1M6FRC1|A0A1M6FRC1_9FIRM PTS system, nitrogen regulatory IIA component OS=Propionispora hippei DSM 15287 GN=SAMN02745170_01532 PE=4 SV=1 -----ALDCIVLHVEAKHKEEVWELLAERLQHSGVIStaEQFVEDVAARESMGTTGVGHGVSIPHAKSAA---VDRAGLAIARLATPVDVNSLDGTKADLFFMVAAPldgIDLNLQMLSTIARMIRHDSFLAALRTAPTAEEMLRIIG--- ->tr|A0A1Q7V0D1|A0A1Q7V0D1_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium 13_1_20CM_3_54_17 GN=AUG52_05015 PE=4 SV=1 -----DEKRVILGLRSRKMPNALREIIDLLAQNGKIDnpEAFFEKVLAREQAHPSVVENSAVFPHARTDL---VDEIVVGIGRSRAGIPFGH-NGVRARLIFVIGVPerlVNDYLICVGTLVRLVRDDATRSALLHAQTPRELIDTLT--- ->tr|A0A1V6FHG8|A0A1V6FHG8_9BACT PTS system fructose-specific EIIABC component OS=Lentisphaerae bacterium ADurb.Bin082 GN=fruA_2 PE=4 SV=1 -----SPSLVKLDVKAQDKEELFEEMVQLFVDNGQITdrESAVATLLEREAKMTTGISRWLGLPHGKLAE---ATGILIAIGVSKKGIDYDSLDGAPVYVVITIFAEmgnPGPHIRALAEISRIFAIHGVIDKIRQAKTPQQVIEIIK--- ->tr|A0A1V5UCN0|A0A1V5UCN0_9BACT Heat-responsive suppressor HrsA OS=bacterium ADurb.Bin243 GN=hrsA PE=4 SV=1 -----DKRNIFVNFCAADKHD---AISKligIMDPGEAISdkADYMASVFEREELGTTGLGDSVAMPHGKSGA---VKKMSVALAKLSQPMDFESIDNSPVSYIFLIASPlnaDTLYIKVMASIIRSVKIHRICEKMNTLESPGEIYEMLL--- ->tr|A0A1V5S959|A0A1V5S959_9BACT PTS system mannose-specific EIIBCA component OS=Candidatus Omnitrophica bacterium ADurb.Bin292 GN=manP PE=4 SV=1 -----KENDLVAGLKASDFKDALTKLVGMIPDwRLGPKmkKDVFQLLVDCERIGTTAIGGGIALPHCLSED---VREPIVMFGVSPDGLVCPSLDGYPVHFIFMLLLPkdeQAELRKRSVLQSAKWMlsDRSLRDELLDARSSADIYDCLA--- ->tr|A0A1Y1RUZ4|A0A1Y1RUZ4_9SPIO Uncharacterized protein OS=Candidatus Marispirochaeta sp. JC444 GN=B4O97_15025 PE=4 SV=1 -----PPSSVLVPLRAETKQEAFDELFAGISMlRTLD-riHGLKEAVLRRELEGNTGIGHGVAMAHGKLQS---LTDIFLCLGISMHGIEYGSYDGEPVRLLFVAANPpsmQGVYLHMLAVLSRYLHLAAFRERIINSEGHI--ARVLL--- ->tr|A0A1D8SGQ0|A0A1D8SGQ0_VIBMI PTS ascorbate transporter subunit IIA OS=Vibrio mimicus GN=VM_17780 PE=4 SV=1 ----ITEKHVALNIATDSPQDAISQVGQLMVNNGLVEPSYIEGMLHIyEEFGPYWvLTHGLAMPHARPE--DGAIESGFVIMTLEQPLNFGHEEHDPVSIVIGMSATdQNKHIENIQQLTQVLNNKQKINMIMQAKEYPEVIEIMNR-- ->tr|A0A1R4B7V3|A0A1R4B7V3_9VIBR Ascorbate-specific phosphotransferase enzyme IIA component OS=Vibrio palustris GN=ulaC PE=4 SV=1 ----INESNIVIStAENLSVDAALDITCSTLIEQGKVETRYLEAIKAKhKEIGAFYvLAPRIAMPHARPE--EGVNEASLQVTVFKHGVDLESEDNGDVFFSVTLAAKdADNHIQTIVALSELFQNEQDIEAIIASESKREIQAILNK-- ->tr|A0A0E3UTL9|A0A0E3UTL9_9FUSO PTS fructose transporter subunit IIC OS=Sneathia amnii GN=VC03_01640 PE=4 SV=1 -----NKKLFIPELGSADKKDVIEKMVDKLYENDCITskEEFLKEVLKREEVAHTAFEGGVATPHAKS--S-VVKKASVVVGISHDGVDFSDGEEEKSKLFFLIAVpvdNPNLHIDVLAKLAGLIEDEGRINNILNADNFEEVLKNIHE-- ->tr|T4P8S7|T4P8S7_CLODI PTS system fructose-specific EIIABC component OS=Clostridioides difficile P28 GN=QSI_0017 PE=4 SV=1 -----ERKNIIITKNIQNKEQLFHYLAEYMVSQKEIDakhqEAFEQALWSREQLSVTGVGNDVAIPHVQK--E-FITRPIVIFLKSETPIAYESIEGDSVRLIFMIAVpehASAKHLNFLAELSRKLMDDDFRKHLLEASDVDALYHIISE-- ->tr|A0A1Q6T4Q0|A0A1Q6T4Q0_9FIRM Uncharacterized protein OS=Subdoligranulum sp. 60_17 GN=BHW54_03670 PE=4 SV=1 -----RPDCVALRQRADSLTGAVQQMVTLLNGTDNLTdtAVFAADVRARLALGGVCVGNGLAIPHAKS--T-AVRQLQLAALTLDPPLPCDTPDGKPLDLLVMIAApaeANDLHVQVLAELATLFLDTDFCACLRESETPEAFCRAISA-- ->tr|A0A1L3RGE1|A0A1L3RGE1_9PROT PTS system, fructose-specific IIBC component OS=Granulibacter bethesdensis GN=GbCGDNIH6_0410 PE=4 SV=1 ---------------PYRGSVAVMTILAIIDGQARRTH----ALLAAEALRKA----------ASNRNRSI--EIDLRVVGSASPEPDTRMI-----STLLLVGeaes-DSTHLDIADKLSAFPKHKTTLDTILA--DADLVLDNIGD-- ->tr|A0A1N6IJU9|A0A1N6IJU9_9LACT PTS system D-fructose-specific IIB component (F1P-forming), Frc family /PTS system D-fructose-specific IIC component (F1P-formi -----NNKKIFLDVDVETKTDLFKFAANQLYDLNLVSnkEKFVKALLNREELSPTGMGDNWAIPHGQDDS---VKAASVLYIRTKKPIVYESLEGNSADKFFFIAVpssTSSDHVKILSKIATLLMEDEFKKSMSNIKNKEDIMTLISN-- ->tr|A0A1Q8F267|A0A1Q8F267_9GAMM PTS 2-O-a-mannosyl-D-glycerate transporter subunit IIABC OS=Aeromonas veronii GN=BTN33_16205 PE=4 SV=1 -----GPHLITLQTRFADRDAAIHALADRLDQAGKLHdkAAFLAAVMAREAQGPTALGEGLAVPHGKCDA---VREAAFAVATLSEKLGWEGIDGPePVNLIFMLAIptdqAGSTHMQLLTTLTTALVDDDTREAVLAAKSAEQLMALLDG-- ->tr|A0A0T9AH71|A0A0T9AH71_STREE Transcriptional regulator, BglG family OS=Streptococcus pneumoniae GN=licR_3 PE=4 SV=1 ------KETYQVSSQKLGWKEAIRLSNTIXXXXPTL---FKELIIIRdFHFCFFfLV------------------------------------------------------------------------------------------- ->tr|E7MN36|E7MN36_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Solobacterium moorei F0204 GN=HMPREF9430_00954 PE=4 SV ------KELTIFTdKVYHDKYEAIEDIAHL--PNEFVNnsDEYAKAVIARENVIATYIGYGIAIPHAISA---AVNQAFVIYVKFLNGCPWANEdGEDRVDHMMMIGVpadkGSTQHLKILAELSKNLMHEDFREKFLNTKSPEESYELLK--- ->tr|A0A1M4ZU10|A0A1M4ZU10_9BACL PTS system, fructose-specific IIA component/PTS system, nitrogen regulatory IIA component OS=Seinonella peptonophila GN=SAMN054 ------QHLIKINTTLNTKSEIFETVCKLLEADNRLLdrQLFLNDLYEREGAGATAPGYSFAIPHAKSK---GVKTASLVFIHLENEIGWTK--SEKVKYIFAIAVpyeeAKDEHLNILAMLARKMMNEDFRKELNAAKTKEEYYRLLT--- ->tr|A0A1T4MAB6|A0A1T4MAB6_9GAMM Uncharacterized protein OS=Oceanospirillum multiglobuliferum GN=BTE48_04195 PE=4 SV=1 ---RLTDIKLPLNHDE--Q---------------ALEQAILRKLAIKKQQLQA-------------------------FTIFRRGY----------------DARNKRDIQLIYTLDvEVTGEAElLAQDSSVRATPDMTYKFVAQ-- ->tr|E3G1D2|E3G1D2_ENTLS Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Enterobacter lignolyticus (strain SCF1) GN=Entcl_2887 PE=4 SV=1 ------FSACQFRERCGTWQEAVKQACLPLEARGMVTPAYAQAIIREtEQQGPWYiLSPAFALPHARPEEGVISDKTHLSLLCLKEAVAFPEH-PEVRLVIVLAAASSIQHLEMIQRLVCWLDEAEHLSQLTRITSPAQLRSVLEV-- ->tr|A0A0U3ULG4|A0A0U3ULG4_9ENTR PTS system mannitol-specific transporter subunit IIA OS=Cedecea neteri GN=cmtB PE=4 SV=1 ------EEKIQYLDNVANWQQAIEVAGRPLLQEGAITQDYIDTIIQQkLEIGPYFvIAPRIAMPHARPEQGAKK--LALSVLKLAQGVSFDADEnDPVDILFMFSAPDSNSHIEMISQLAEVLSDEEKMAQIFSSTNQAELSTHLLS-- ->tr|A0A242NYY9|A0A242NYY9_9GAMM Uncharacterized protein OS=Gilliamella sp. A7 GN=B6D18_09545 PE=4 SV=1 ------EQHWQFSKENLDWKSAIQIVGNSLIENNHIEQRYITSIIDNvNEIGAYFiIADGFALPHARSENGVICEDTKFSLLKCTHPVIFPDG-EKISLLIMLAASDNNKHIDAMSDLIEWLDEDDRLDNLINVDNVDDFECLLFQ-- ->tr|A0A124INM4|A0A124INM4_9FIRM Uncharacterized protein OS=Clostridia bacterium BRH_c25 GN=APF77_00550 PE=4 SV=1 ------EDLILLNVEGDTRDEVLNNISIALLEKGVVKKSFASALIKRENEYPTGIPigeYNVAIPHTYP---EHNNEIAVTIAVPKKPVQFYNMGNseELlKvYVIICLSFEkMDDSVKMLSSLMTFFGNEENVKAVMVCRDTSEVLKVIRS-- ->tr|W7CJ07|W7CJ07_9LIST PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_07350 PE=4 SV= ------TKLLYVQQQEDSVETIFKTICKKAQQLGYTKASYFNALQTRELSYPTGLAlphCGIAIPHTDF---NHVKQPFISVMTLRKPVFFHAMDGvnGVaVQIVFVLGLTtTTAQLASLKAVMAICRSETRVEQLLHATDASELFAILTK-- ->tr|G4L9I9|G4L9I9_TETHN Putative arabitol-specific phosphotransferase system enzyme IIA component OS=Tetragenococcus halophilus (strain DSM 20338 / JCM ------KELVFLDIESPNANELFKIIADELQNKGFVNEKYHDGLINREKDFPTGLQledYSVSIPHTDP---ETVKKDFIAIVRPRSPIMFSLMEDndKKtPvDLCFFIGLRdGKKSPLALMELISLIQNHKLILSILNEKNREKIIEKIQE-- ->tr|A0A0E3Z9S9|A0A0E3Z9S9_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_02315 PE=4 SV=1 ------KEDIYFNVEAENREDLIRKMSKIFKEQGYIKDGYEESLIEREKNYPTGLNfekYFVAIPHTTY---SLINSQRIVFVRLKNEVEFGEMGTneKQlKvKVVLFLLIKkGEEQVTVLLNLMKILGDEDCYNTLEKSEDKEEVYNILVN-- ->tr|A8RYB6|A8RYB6_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_05080 PE=4 SV=1 ------NRYLVIHGFARDRYEAITMCGEALYKEGLVSEQFGTLCVEREKNYPTGLPteIPTAIPHAKD---ESITQNSVCFLKLDRPVSFKRMDDdtqDVsTDMIFNLAIKdPNEHLQALQNMMGFLNDSEALLKCKSLSDEELI-EYLQE-- ->tr|A0A1C6ASB9|A0A1C6ASB9_9FIRM Pseudo-HPr OS=uncultured Flavonifractor sp. GN=fruB PE=4 SV=1 ------SSCVQLDVKAQDWQDAIRKACRPLMNEGFVTEGYDEDVIARELQWATGLPtepVGVAIPHSLTP--QHVITAQIAACRLSQPVKFAQSGGtaddgKVdVSIIFVLALKdPKEQLSLLQKLMAAISNEEMLASLMGTSAPLEFSNIFNG-- ->tr|A0A1H1DN47|A0A1H1DN47_9ACTN PTS system IIA component, Gat family OS=Tsukamurella pulmonis GN=SAMN04489765_1800 PE=4 SV=1 ------THDTLLDFTAEDPATVIRAVGAVLNDAGTVTPDYVEAMLDRETQYPTGLAtepVAIAVPHATAG--DAVLHSSIGFARLSPPVAFAEMGTsdgrTVdVGFVFALAVSPDEHLGTLTSLLRLAQEESDLLSEA---TVEAITAAIGR-- ->tr|A0A1C5P2R9|A0A1C5P2R9_9CLOT Putative PTS system EIIABC component OS=uncultured Clostridium sp. GN=hrsA PE=4 SV=1 ------ENIIRIGIDAKDKDDALHKMAGLLYENQYIDdiEGFVKDVYAREAEGETGLGQGVAIPHGESK---NAQKLGVAIVTLNHPIEWETLDGGKVDTIFLFCVSSdanfaRNHMLLLSKIAARLADDDLLKQIRVASSSCEMIALLAGE- ->tr|A0A1G4FP56|A0A1G4FP56_9FIRM Putative PTS system EIIABC component OS=Sporanaerobacter sp. PP17-6a GN=hrsA PE=4 SV=1 ------EDNILLNIKLNSKEEVINKLSDLLVNSKAVSekEGFIKDIYERESRGFTYAGDYLAIPHGWSE---YVIKPAMAIAKTDTAFAWDK-DGNLVKLVIMFVIPEntemENNLKKIGKIFSALGDTKLVKKLLKLNTKKEIIEFICSI- ->tr|A0A1Q6N4L4|A0A1Q6N4L4_9FIRM PTS sugar transporter OS=Clostridiales bacterium 42_27 GN=BHV90_14280 PE=4 SV=1 ------DEMVILDCEPFKDkENMFDVMTAKFEEAGFVSdaKAYKDALEYRESLGPTYMGNFVAIPHGKCK---EVLKPGIGFCRCKKPFIYESSGEsGEVKYIFVLAISEnqenDYHLRVLATLAGMLAHEEFLELLEKAESYDDLIHGIKQL- ->tr|A0A1R1CUM7|A0A1R1CUM7_9BACL Uncharacterized protein OS=Paenibacillus sp. FSL H8-0548 GN=BK133_20045 PE=4 SV=1 -----SKQNIFLNLQSIPKTEAIQLAGEKLVELGYVAENYIASMHEKEKVKSTYLGNGVSTPHGSKIAKEAVVKSGVVILHFPNGIDYENGE--KVYIMIGIAAERSYHLDVLMKAATMFEMKGNADKVANATSIEEFIQRF---- ->tr|G1VV57|G1VV57_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_03976 PE=4 SV=1 ------RECILPHYAAQQKEDIIQELSKRMKERNLVNADFQEAVLKREQKYPTGLLIgkrNIAIPHTEP---QYVKVPCIGIATLKKSVAFHRMDACdelVdVDVVLLLALnQAHAHMEMLSRIILMCQDEAFIEELMRAEQETDIEQIVRE-- ->tr|A0A0A6VD84|A0A0A6VD84_9BACI Uncharacterized protein OS=Bacillus ginsengihumi GN=NG54_15130 PE=4 SV=1 ------KIIVNTRLQVGNCKEIIERLGVQMLEAGYVKDTYIEAVLQREDILPTGLKTglvNVAIPHTDV---THVNESAISMTTLNRPVKFYLMEDPsqeIdVDIVFLLAVkEPEEQVQLLKNLIAIFQNEELLAQMKDIEDENSLNQVIKA-- ->tr|A0A0U5NXP3|A0A0U5NXP3_9CLOT PTS system galactitol-specific transporter subunit IIA OS=Clostridium sp. C105KSO13 GN=BN3456_01882 PE=4 SV=1 ------RKDTIFFiddDKEYTDKEVLHIIGKKLLDRGYVKESFGEALLEREANYPTGLAMmpyPVAIPHTDP---GHVNEPCISIVRIKQGAVFHEMVNSesiVkVNFVFCIALqVADKQTGVLQYLMQVAGDDSIMNIIKNAKNADEIYKVVSI-- ->tr|A0A0F4WKU3|A0A0F4WKU3_9CLOT Uncharacterized protein OS=Clostridium sp. IBUN22A GN=ClosIBUN22A_CONTIG144g03033 PE=4 SV=1 ------EKDLIFKEDFVSLDQAFKCLSKKFLERGLVKQGYLEALMEREKNYPTGIDLtavfqgfpNIAIPHTES---KYCNATKVIVIKLERDIVSKDMMNPdkdLnVKYLFMILNkDGGEQSNILAKIMEFATNKENISMLAASDSLDSIYDVVNK-- ->tr|D1AKT3|D1AKT3_SEBTE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0214 ------NRCIELKSNYDSYEDLITNVSRELLKYGYVKESFLENILGREKQYPTGFELggkyNIAIPHTDM---ENVLKPVIYIVVLDRPVMFKSAEDGksdIsVDIVFVISLnEKDKHIVVLEELMKIFSKNDLIEKIKNSEDKDELIRLIYE-- ->tr|A0A0B3BAI0|A0A0B3BAI0_9THEO PTS system IIA component, Gat family OS=Thermoanaerobacter sp. YS13 GN=THYS13_18260 PE=4 SV=1 ------DVLIFTEEVEGNREEVLSHIAEILLEKGFVKKGYKESLLEREKYFPTGLYVdeelKVAIPHTEV---NFANKNVLVVVKPLNSVHFYRMDKPdveIeVDIIFALVIkDSHEYLKFLSKLTENLTNEEFVKLIKTG-NLENISAYIKN-- ->tr|S2S8D1|S2S8D1_LACPA PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein OS=Lactobacillus paracasei subsp. parac ------RNLVLNRVDAVNQKELFDLAASKLLMEGYVKQTYLEGLTTRESKFPTGLKTksiDVAIPHCDP---EYIDKDGVLVVRPIKPIIFNEMVNPtnsVqSRLIFFICStGGTEQLESLRQMMNIFKDDKFLTTLYQAEDMMPLLFSWKG-- ->tr|G5HDM8|G5HDM8_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00690 PE=4 SV=1 ------ENIFVMDGSADSWEDAIQICTERLIEEGVVKPSFKEACLKREQAFPTGLPTapGVAIPHAGN---EHVYENGICLLRLKHPVLFQRLDVPeetVpVNFVYNLATsESEGHIDILKKLMESIHSGQILKDYMDVPLEQLYDMVYKQ-- ->tr|A0A1C6B6L1|A0A1C6B6L1_9FIRM Multiphosphoryl transfer protein 1 OS=uncultured Ruminococcus sp. GN=fryA PE=4 SV=1 ------DNLVFHNLKASDNIEVLQLMGDAMIQEGYGEEGFTEAVLKREKDYPTGLDVngiGVAIPHTDA---EHVKKEGLSIAVLNPPIEFDAMGEEdcrIpVKIVIMFTVaGKDKHIDRLLQVLDMIKDEEILQGLLDAKNKKEIRTVIQK-- ->tr|A0A1J0H4N9|A0A1J0H4N9_VIRHA Uncharacterized protein OS=Virgibacillus halodenitrificans GN=BME96_15085 PE=4 SV=1 ------KDIFMMNLTVGTKEQALTAMCSMLINTGYVTADFMEEILKREQGFPTGLPVqpyGVAVPHVDS---KHVIESQVVFAALKKPVVFQQMGNNqqnIdVSFIFMLAFrDPTEHLQHLQKLFLCLQDTAFMQQLNQIKNKSHLLQLINN-- ->tr|A0A1J7VRH9|A0A1J7VRH9_STRAG PTS galactose transporter subunit IIA OS=Streptococcus agalactiae serogroup III GN=A9249_07340 PE=4 SV=1 ------TQDILFI-DAHSQEELFDLVSKALIKQHYVSPDYRQAVKEREREFPTGLKIdlkdgtpiqYVAIPHTET---QYCLVDRIFYVKNSQPITFKHMINPeeeCrVQDFFFIINsRNSNQSDILSNLITFFITKGNLDRLHELGDNKeKINHYLIE-- ->tr|A0A140DZ70|A0A140DZ70_MYCMY Mannitol-specific phosphotransferase enzyme IIA component OS=Mycoplasma mycoides subsp. mycoides GN=mtlF PE=4 SV=1 ----NIYKKIYLNKTFNSKQECLDYLKELLKQEN-VSLEYIDSINKREEDCSFNIGSKIAIPHGIYEGMLSLKNSLIVVIHLQKPLIWDNSE---VQLVIGLALKQEDQIDMLQNIAINAMNDDLFNDLLKNPTIDKVISFCT--- ->tr|A0A084U359|A0A084U359_MYCIO PTS system, mannitol-specific IIA component OS=Mycoplasma iowae DK-CPA GN=P271_228 PE=4 SV=1 ----LNTNNILIGVDIKNKNDAFNKVFECLKKQNAIEDKYLNSMIERDKNSSVAIGNFIAIAHGTVETKDLIKKDAMCILVLKNPIDWDGNE---VKVVLGLALSGDKTMDVIGNIGVAFSDEEEVKNFYYKNDltSNEVLKWLV--- ->sp|P75145|PTMA_MYCPN Mannitol-specific phosphotransferase enzyme IIA component OS=Mycoplasma pneumoniae (strain ATCC 29342 / M129) GN=mtlF PE=3 SV=1 ----LLKNNIYINVYLKNKQEIFEFVFKKFKEDGAVLDSFLPAIVERDKAASVAIGNYLFLPHPVYDEIANIQKEKMVFIGLKDVINIDGQP---IKFICGLALKGEHQMDALQSLAIAFSDPEEVEKLVKDKDltQDKVLEFLA--- ->tr|E5VQI2|E5VQI2_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase OS=Anaerostipes sp. 3_2_56FAA GN=HMPREF1011_00254 PE=4 SV=1 ------EDLIWLDETFEDKDQFFDKIGKRLYEKGKVKESFADGLKSREAVYPTGLkteSYEIAIPHTDV---EHVREASISFVRFKETVLFSHMGEPeiqvNAKFAFVLGVKEpSQQVEVLSTLVLLISNEAEMAKLEVLNAPAQICALLNE-- ->tr|A0A0K8JBW2|A0A0K8JBW2_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_1074 PE=4 SV=1 ------EKLVKVGVQVPSREALITAMGTMLVEQGFVKPSYIPALLAREKEFPTGIaaaaGVGVAIPHSDA---GHVLKTAASVWVLDKSIPFHVMGGGqedilEVNIVFMLAVHNpQEHLMFLQKLLGLFSKEDVMLKLRNAANATCIAETINL-- ->tr|A0A135PBN0|A0A135PBN0_9ACTN Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Atopobium vaginae GN=HMPREF3232_00779 PE=4 SV=1 ------REMIFPKLEFDSRTEVLQYMAHQFTKLDLAKESYAAALIEREAHFPTGIsarAFDIAIPHCAS---ENVNRTSMAVATLTHSVGWHAMDDPnkilQPTVVFMLAIKDpDKQIETLQKIMEIIQNSQLLQDISVAVTRDEIFSKLDP-- ->tr|A0A094Q411|A0A094Q411_9ACTN Uncharacterized protein OS=actinobacterium acAMD-5 GN=GM45_2780 PE=4 SV=1 ------DDFCSASLKADSALDALTQIATLGYENNLVAQSWLAAVTQREQDFPTGLpta-VPVAIPHTDS---IHVKQDGIGYFRLTQPVEFGEMGSLenkiKVSVIIPLLITNpKDQTSLLMSVIALVQDFEFMNQLILLDSKTQVANFLNE-- ->tr|G5IKK0|G5IKK0_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_04028 PE=4 SV=1 ------KKGFFQKKRYDSRQDYLSNTADMLEREGLVKEGFKKVLMDREDNYPTGIqtiTVPVSIPHAEF---SYVNQESIVVTVFEKPVLFRRMDAPeeevGAEISFMLLLRDaHSHLTVLQQLSGLLQSDKL-ARIRETDSMEKLAQILQE-- ->tr|R2QDF1|R2QDF1_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_02157 PE=4 SV=1 ------KDFLYCQYTVKNKEELFDRLTGDLMAKNIVREGFSQALKDREAEFPTGLpvk-HGVAIPHTDG---SLVNSDQLLFVTLTEPIIFNEMGGDdedtvEVNVVVMLAVKDgKKHLTVLQNLIEAIQKEGFVDQLVDATDEEQILAAVNA-- ->tr|S0JCP9|S0JCP9_9ENTE Uncharacterized protein OS=Enterococcus saccharolyticus subsp. saccharolyticus ATCC 43076 GN=OMQ_02130 PE=4 SV=1 ------KKEIMYQTNFQTKEELFQGVTAFLVDKGFATAEFEAALREREERFPTGLpse-PPAAIPHSDG---TYAKEDVIVGILNEQPLEFYQMGTNkstllHPRIVFVLLVRDkVTHLDQLQRIIEKAKDHDFLVRLQDASDEGQFTSLIQE-- ->tr|A0A0D6JLB6|A0A0D6JLB6_9EURY PTS system galactitol-specific transporter subunit IIA OS=Haloferax massiliensis GN=BN996_00126 PE=4 SV=1 ------MRTESLELTGETDEAVLTELGAYAYDRGWADESYADALLAREADYPTGLdiptmGFGIAIPHADP---DHVSEQAVLLglPPAGESVAFRSMDNPdervDAEVVVLLLVTDtEGYSSFLSNLAKLFQAEEFAELTKRRDADG-LLDLVVE-- ->tr|A0A1N6R1X4|A0A1N6R1X4_9SPIO PTS system IIA component, Gat family OS=Spirochaeta americana GN=SAMN05920897_105136 PE=4 SV=1 ------PSLVLDDLAGDSREEILRTMAEYLVKEGRCRRTFVEAILARERLYPSGLpleGPKIAIPHTDT---IHVHRSALLFVRLRTPVEFASMGDPkvtfPVQLVSMFALQNdDLVGNVLQTLITLYQRRQMLEDLLRSKDAREMYQILVS-- ->tr|A0A1Y4L6S6|A0A1Y4L6S6_9CLOT Uncharacterized protein OS=Butyricicoccus pullicaecorum GN=B5F17_09040 PE=4 SV=1 ------EKNIILDCDAQNWEQVIRIAGARLRENGYIDDAYIEAIIEREKEYPTGLptdDVITALPHANS---GAVYKTGVCAVRLAHPVDFRNMGDPeetlPVEMAFVLANAsGpDAHLEDLQELMDCFTRVGLLADLKRAQSVAAFQEVFAA-- ->tr|A0A1Y3U0P5|A0A1Y3U0P5_9ACTN PTS galactitol transporter subunit IIA OS=Enorma massiliensis GN=B5G21_07690 PE=4 SV=1 ------SLVRIFNENALDTYSVEEELAGALCAGGWVKETYANALHEREEAFPTALdaqGINVAIPHCET---EHVNQGAVAVGVLKHPVSWRRMDDSsqtcDVSLVVMLALVEaHAHLEMLQKVIAIVQDQEFVGTVIAQDEPQEVYRLLSD-- ->tr|C3WAJ2|C3WAJ2_FUSMR Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_00441 PE=4 ------KQI--IVTDLTTKQDFFKTIADLAFENNILSDkeEVILGLNERESKGSTGLLDGFAIPHAQT---PSIKKAAVVIVKSTNKVGWESLDGEPINTAICLLVpksqAGTTHIDFLTEISKLLMDDDFRANLNKLNDSHSIYEAFL--- ->tr|A0A0M2ALT6|A0A0M2ALT6_ENTFC PTS system ascorbate-specific transporter subunit IIA OS=Enterococcus faecium EnGen0153 GN=SIE_00828 PE=4 SV=1 -------EMIQLSDQPKNWQEAITFAAQPLLSLVALMYVLQRYEFllyqldkSAIFHMDVfvH-------------------------------------------------------------------------------------------- ->tr|H9UFA3|H9UFA3_SPIAZ Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Spirochaeta africana (strain ATCC 700263 / DSM ----FDNGSVVWELESETKYDAIHEVIYRSPIFRNlpGfdLDQFYQVVHHRESLQSTGFGHGVAVAHGRTPM---VADSVVALGVSRQGIDYQAMDNRPVHLLFVVATHPDqqlNYLKVLSSLITLVRQESFRREIFACLCQEEIEEKLCH-- ->tr|F2LUE8|F2LUE8_HIPMA Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Hippea maritima (strain ATCC 700847 / DSM 10411 / MH2) GN=Hipma_0503 ----IN--TVKLNINCKEKFECLKKMAEYLAKEN-NlnSEDVFSLLMAREKFGSTAVGGYFALPHAKMDS---LSKLICGIFTTEEPIDFGSLDGVPSQIFLVVLAPSSkpsILLKALAKAAKIFKDNQLKERIISEKDKEKVIEFIKN-- ->tr|A0A0F9RK65|A0A0F9RK65_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0634850 PE=4 SV=1 ----LTQDMIILELESENAEGILREMVRFLRK--KdiVskEKELYEKLVQREKLGSTAIGEGIAIPHCKIKR---VKNPVVMLAISKKSVDFCSLDGKPSNIFFMVVSSPDnpsINLQILAAIAHLVRKSgSLAKKILKAKNISAVMDVIRE-- ->tr|A0A0S7XI28|A0A0S7XI28_9BACT Uncharacterized protein OS=Latescibacteria bacterium DG_63 GN=AMJ46_00825 PE=4 SV=1 ----LNEKAICTSLKSSAKEEVIEELVNLLEEAHGidSGGEILNRVVEREAMMSTGIGNGVAIPHGKARS---IHSLLAACGIAPEGLDFQSVDGESVILFILLVSPEEfrgPHVRALANISRLLKEEDTREHLKRSASAQEFLEVLKQ-- ->tr|B6G220|B6G220_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_02182 PE=4 -----MKESIILNFDLnekyISKEELFKEITKLLHNNNCIelENKFLEELLYRESLGSTAIGNEFAIPHATYEKGANIPC--IIVCKLKYSIKWDDAGKFFVKNIILFANPKLevnkKGLKLMASICRTLANEEICIKMSNMKCSKEMANFIYD-- ->tr|G8QYK7|G8QYK7_SPHPG Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 ----LDKDLVKVPLNAIDKLGIIGELVDVVTKAKGysSqqHDDILNAVLSRESLGSTGIGNGIAIPHAKTDA---VDHVSMVVGISRIPVDFSSPDEVKSKIFFLVLAPSKeasAHVELLASIARTCTSQIFRRMLEQSKNRDEVVRLFME-- ->tr|A0A1F4X9W2|A0A1F4X9W2_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium RBG_16_50_21 GN=A2Z27_04045 PE=4 SV=1 ----IHPDLIKVELETavpeeveeilkpeirveRIKELLVKEFVEILSLSGKIqsSNKLYLDLLNRERKASTAIGHGVAIPHVRTMH---AREFVMGLAKSTEGYEFGSPDGQRVHLFFLMVSPNYddnLYLKVYKGLADLLKYEELREKLLHASSVREVIGALQK-- ->tr|A0A1G3R8N1|A0A1G3R8N1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_68_11 GN=A2177_13905 PE=4 SV=1 ----IARERIA-FIEAENKQDALAKLIALSEDDRLvIdFNQFQNAVLDREYIVTTGIGQNVAIPHIKSRW---VRDFFISIGVFRNGVEWQSLDEKPVHLAFLIAGPEEheRYLRILAKLTLIIRDKEKRKAIIGASSPDEVYRLLEN-- ->tr|A0A1G3QED9|A0A1G3QED9_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_51_14 GN=A2176_02325 PE=4 SV=1 ----LKRQNIFLKAKSTNRWDLINEMVDLAAKNREvePsdSDEIKKSLIDREKSMSTGIGNGVAIPHCTTAK---VQDIIIVISIIPRGLDFDSIDNQPVKIVILLLVPKNkltQHIKTLANIAKLMSNENLRNKLLAIKTPDGIIKTIKD-- ->tr|A0A1G1M315|A0A1G1M315_9BACT Uncharacterized protein OS=Omnitrophica bacterium RIFOXYB12_FULL_50_7 GN=A2351_03360 PE=4 SV=1 ----LHEENIVVGLDALNHEDALKKIVDVLPGWSLqGieKQKILELLILRERIGTTAIGHGIALPHCFSSE---VHEPIVAFGVSSSGVPFPSLDGRPVHFIFVLILPRNdaaERQKrqILQNIKWSLCDRYLQERLKGAQTASEIHRLIVS-- ->tr|A0A1M6M9C8|A0A1M6M9C8_9BACT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Rubritalea squalenifaciens DSM 18772 GN=SAMN02745 ----LTVEQVMLDMKSEEHWPAIVELVEHLDKEGLlaPenKEDVLAALQVREDQISTGIGSGVAIPHAFSDK---LEHVVAMFGRSKDGIDFEALDNAPVNFVLLFVVPKKdyhMHLQTLAAIAKMFNNCEVRQQLAEAETRRDILEILGS-- ->tr|A0A1Q2HQI4|A0A1Q2HQI4_9BACT EIIABC-Fru OS=Phycisphaerae bacterium L21-RPul-D3 GN=fruA_2 PE=4 SV=1 ----VCPEAIVVKLKSTDRDGVITELVDSLVESGQldKdkRDQAVKAVIDRENEASTGIGKGVAVPHVKSSL---ADTPIGAFGLSSEGIDFLSLDKQLVYSVFLVIGPEAnpdQHLLAMEIIFKNLQKDDFRSFLRQSKSTEDVVTLLEE-- ->tr|A0A1V4QT45|A0A1V4QT45_9BACT Uncharacterized protein OS=Candidatus Latescibacteria bacterium 4484_107 GN=B1H02_06030 PE=4 SV=1 ----LDASNVVLNIEGKRRTQIIEKIIQQLHHAGAAfdEEEALEKVLKREELGGTGIGFGVALPHARLNS---AEDILVGLGISKKGIDFEAMDGQPARLIFLVLAPEKeaeTYLKVMARISRLMRKEEVREELLCCDIESDVASIIEK-- ->tr|A0A1T4JW83|A0A1T4JW83_9FUSO PTS system, nitrogen regulatory IIA component OS=Cetobacterium ceti GN=SAMN02745174_00123 PE=4 SV=1 ----FNSKLITLIDNKnSSKDDILKDMVHLIKENTNyLedEEDFYNQIIEREKVGSTGIGMGIAIPHARSQA---LDKIVVAIGLLKTPVNFNSLDGEYVKVVVLVGAPKEqskEYLGLLSTLARIFRNKKSRESIMDSSTLEELIEAIAE-- ->tr|A0A1W9S016|A0A1W9S016_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium 4484_93 GN=B6D65_00270 PE=4 SV=1 ----LKEETVNLNITQgklpdkptedytnadrwRMKENVIRQIVELVEHSGLVgnKKKLLLDFVNREKRCTTAIGSGIAIPHIRTMQ---VRGFVFAIGISKDGVYFASMDGAPTHIFFILASPPYddtDYLQIYRRISELVQNQNIFFELTTAGTPGELIRIVKD-- ->tr|A0A1W9RCL1|A0A1W9RCL1_9BACT Uncharacterized protein OS=Candidatus Omnitrophica bacterium 4484_70.1 GN=B6D56_00335 PE=4 SV=1 ----LDKRDILFKIKGKGKKSVITFFVDHLISTKKvdKkyRKEIIKSLLQREEMGSTAIGGGVALPHARLES---VKKVVLCLGISPQGINFDSLDGEPVYIIALLLSHHKeagLHLKILALLARILKDKYFVQRLKEVSQQEEVISLLRR-- ->tr|A0A1V6BYM8|A0A1V6BYM8_9SPIR PTS system fructose-specific EIIABC component OS=Spirochaetes bacterium ADurb.Bin133 GN=fruA_1 PE=4 SV=1 ----LKVEHCKIGINAKSKDDILHELAEFLSASHkGIidKEDAYKSLKERENKGSTGIGKGLAVPHGQSDK---LNGIALIIAYDKNGKDFNSYDNRPTHLFFVGITSSEynpnDHLKLLKIIAAIFEKSNIAQQLETVKEPADIYNLIIK-- ->tr|A0A1V6EUJ0|A0A1V6EUJ0_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Cloacimonetes bacterium ADurb.Bin089 GN=fruA PE=4 SV=1 ----FMPELIKIVEQFENKNACLQYMANLLSESGCLsfPDRFLAAVKGREEIMSTGIGRGIAIPHARDLT---VSCLRIAVCLVKQDLEFTSLDNSPVHLVFMIAVPQSsnqDYMKILRSLSEFLRQDENREILLQAKDERDLYEKVQI-- ->tr|A0A1F6CQ84|A0A1F6CQ84_HANXR Uncharacterized protein OS=Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10) GN=A3F84_22585 PE=4 SV=1 ---------MILHLQAQKRMEAIRELASRLEGSDEIvdVKRFLSLVMQREKIETTAVGHGVAIPHAHGDC---VKSLVIGVGVSRQGIDFGAMDGEQVGIVVMIASPVRhfqDYLKAVSRVARLLNQEDCRQRILNAQGVAEVIEVFKQ-- ->tr|A0A1Z9N4K8|A0A1Z9N4K8_9FLAO Uncharacterized protein OS=Flavobacteriaceae bacterium TMED208 GN=CBD68_05510 PE=4 SV=1 ----LIPAFIELNIEVQNKFQLISSLVDKFDQKG-iLseKKEYLDAVLERENLLSTYCGYNVAIPHAVSKS---VKNSAFGFCRT-KPMEWDKNDEHVQ-FILILAIPdssNSnesKHIDMMSQIASLALEEEIRKIWKSAKSKDVITKTFN--- ->tr|K6PGJ9|K6PGJ9_LACCA PTS system, fructose-specific IIABC component OS=Lactobacillus casei 21/1 GN=LCA211_2417 PE=4 SV=1 ------NDLIILDQDYSSKREVFQAVADRLKQKGTISntSNFIDSLYAREKDGPTGMDKGVAIPHAKSS---QIKEPVFSIVRTKKPIdDWESIQPdNKVSLIFLLAIPksdaGDFQVKLLAKLSRAMLDDQFISTVMKASSTGQVMAELGR-- ->tr|D0IAK8|D0IAK8_GRIHO Phosphotransferase system fructose-specific IIB and IIC subunit OS=Grimontia hollisae CIP 101886 GN=VHA_002785 PE=4 SV=1 -------------------------MKAIIVT------------SCPSGIANTIIAAGLLEKASAALQWTVTVECQ---TTVKATEKLTQSAIEAAELIIAVgPVSdmarFTGKKVYQAELSACYSDAKQLLEHAA-----MNASVYTH-- ->tr|A0A1B7L9G8|A0A1B7L9G8_9ENTR PTS fructose transporter subunit IIBC OS=Mangrovibacter sp. MP23 GN=A9B99_04655 PE=4 SV=1 -------------------------MKTLLII------------DPGLGQARCYLAKTLVAAAA-----------------KKANLEIIDNP-NEAEMAVVVgtEIKpdtaLNGKKVFLGNIDRAVQHPELFLNEAK-----EKAVVYTA-- ->tr|A0A1L4DE60|A0A1L4DE60_BORAF PTS fructose transporter subunit IIA OS=Borreliella afzelii GN=BLA32_01095 PE=4 SV=1 -----SKNLIALNYNATSKEDVIRKMASMLNENGYLNdmEAFIKEIKKREEINGTGIEEHIAMPHAKGDF---IKKHGIAILRInGNGFDFNSSDQKLSKLFFMMALPeeiPsNAHIKAISYLSNTFSNNLLRHELMNTNNEDRFLEIIMN-- ->tr|A0A1B9LID7|A0A1B9LID7_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G11_12910 PE=4 SV=1 -------SLITLDVDCQTAEQAIERAGELLVKAQLCTDDYVSAMKQVYQNFGAYivLDNAIAMPHARPEH--GAKATGFSIITLKNPIEFGNEDFDPVTVVVAIVSNElDAHVDLIQLIATLIEND-LVSVAQRSTTPQSLVNFVE--- ->tr|E7G924|E7G924_9FIRM PTS system protein OS=Coprobacillus sp. 29_1 GN=HMPREF9488_01262 PE=4 SV=1 -----------TEKNVSSDLEAIEVAGSVLVQEGRVMPEFITACTDREKIYPTGLglpsGQAVAMPHGES---SFVKEDSISIVRTQTPVVFKRMEDPDQtvkcQLIFNLAlATGGKHITVLRKLMGLFQDEMFIQNCM-QYDNISLIK------ ->tr|A0A1Y3XXS2|A0A1Y3XXS2_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_00875 PE=4 SV=1 -----------DADAPATWEEALRTLGAAFVEHGCATPEYIEAAVTRERAFPTGLdlgAWAVALPHGDP---IGVLHGAISVGRFERPVRFRRMDDAERevevEAVFFMAvDDPERHLAVLSKLMEVIGSGSCRREMLVAYDGEAIAN------ ->tr|A0A0R1KE09|A0A0R1KE09_9LACO Phosphotransferase system mannitol fructose-specific IIA domain containing protein OS=Lactobacillus paralimentarius DSM 19674 G -----KENLIKLHVKSHDWKEAIKLSAQPLVDDEIVTSNYVNEIINSVNeYGPYfVIAPHVALAHAPGKA--GAKELAMGISVLEPAIEFNNADNDPVSYVFTLSAPdSNSHLKAMQELVYLLTDDNFYQVLSNSQKPSEILQYIKDSV ->tr|R6UZB6|R6UZB6_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium CAG:64 GN=BN746_03528 PE=4 SV=1 -----KEENVEVGVHAADWEDAIRRSAQHLLETGKIEERYIRAMIDAVHrVGPYiVLGNHVALAHARPEC--GVNELSVHFTTLQPPIPFGSEKFDPVSLIITLAAVdADSHLELISELADILMEETHVERLSSCTTEREFVELLRRMK ->tr|K1XNA3|K1XNA3_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_79C01047G0003 PE=4 SV=1 ----LINDGIVLEPKISNKWLILEQLTGFFCRQLPLSiaDQILETVLNREMIVSTGLGGGIAIPHARTDLVQ---KTELLFARFKSGVEWNSIDGSSVNFLFLVIGPtssAEEYLFVLSKISKLLSRKQNKDELLHAKSSKEIYMILSS-- ->tr|A0A0J7HTL9|A0A0J7HTL9_9BACT Phosphotransferase system mannitol/fructose-specifc IIA component OS=Chitinispirillum alkaliphilum GN=CHISP_1303 PE=4 SV=1 ----LPKNAILTDIKKTDKNEVLRDMTHFMASLYNLnhd-pEILTQKILEREAEISTGIGYGIAIPHVRLAGID---RCYMAAARSKTGIDFNAIDDQPVHMLFMLFSPvntSTEHTQILSSLSRIMTWEEIREKLLQVDEAQEFLDVLTE-- ->tr|I0XAB0|I0XAB0_9SPIO Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Treponema sp. JC4 GN=MSI_08290 PE=4 SV=1 ----ITPSDINLNLESTDKEEAFAELTEMLVKKCPGln-rTEYMKAVTERENKCSTAVFPKVAVPHAVCDSAS---KTTIVVGISHDGIEFEPLESAdntnpVVNIIFQIVFErenTGSHLNVLRDILYIVSKPEFYEKILTLKTQKEIFDLFTE-- ->tr|D3PD43|D3PD43_DEFDS PTS system, fructose-specific enzyme II, A component OS=Deferribacter desulfuricans (strain DSM 14783 / JCM 11476 / NBRC 101012 ----VDEKHVIFIDEKLDKDALLKLFAEKFRELDAISdsQAIFEALYERELLSSTAVGEEVAIPHAKLANLD---DIKMIIAISKVGQDFQAVDNLPVKLFFVVIAPankMQLHLKALARISRLVKMTDFKKRALEQDSAKKVIDILVE-- ->tr|G7Q482|G7Q482_9DELT Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfovibrio sp. FW1012B GN=DFW101_0936 PE=4 SV=1 ----LQPEFVIGELAAESKSEVLAELVAKIAAGLPGFdaKRAHQVLLDRESLGTTGIGDTVAIPHGKMESLE---KIVIAVGRSLKGVNFDALDFKPCRIFFLVLAPehvAGLHLRILAHISRLLSDESFRHAFLSAENDAALWQVLTA-- ->tr|A0A192X050|A0A192X050_9BACT Uncharacterized protein OS=Acidobacteria bacterium Mor1 GN=ABI59_16845 PE=4 SV=1 --------MVRVGLEAVDRLGLFRALVGDLAAREEFQnqQAVFDAVVHREGQRSTAVGEGFALPHATSEHVP---GLLMAAARLARPIEFEAPDKEPVDLVFLVLAPpaeMAPFLVLLGRLARVVSRKDVASDLRSAPDEESFEAKLQE-- ->tr|X0TWP6|X0TWP6_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S01H1_29742 PE=4 SV=1 ----LKENNIFFDLEPGEKRHVLEEFVSALKKRGLIs-neKVILEELLKRESLGSTGLEKGIAIPHALIENID---DPIVALALIKSGVNFDAVDQMPTYIILLLLGGkdnPGFQLRLIAHICRMVKETDFVEKAKKAESSHD--------- ->tr|A0A1G3R026|A0A1G3R026_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_68_11 GN=A2177_03875 PE=4 SV=1 ----VHPECFIHDLAAKTREEALREIVSVAAAKGIIKdqAAVLERLLERERIQSTAVGSGIAIPHCFTDEVA---DLVIVVARAPGGIAFDSFDGRPTHVVFLLMGNrqeHGLHLKALARIARLIKSTAFIDRVVAADSVEGMVRAFEE-- ->tr|A0A1F5FHA6|A0A1F5FHA6_9BACT Uncharacterized protein OS=Candidatus Coatesbacteria bacterium RBG_13_66_14 GN=A2Y64_04185 PE=4 SV=1 ----IEKKAVLLELKAGTKDELLKALIGAVGRSSRVKdpAAAREAILEREELSSTGMGYGVAMPHARVKSVT---FPVLGFARLAGGVDYGSVDSEPVRLVFLLLTPatnPELNVQLLGKISRICQREDNRRRLLGVEKTGDFLTFIRE-- ->tr|A0A1G1KR18|A0A1G1KR18_9BACT Uncharacterized protein OS=Omnitrophica bacterium RIFCSPLOWO2_01_FULL_45_24 GN=A3K16_04305 PE=4 SV=1 ----FKKDFCSLDLKAATKEGAIREIAALLSKSGKLkd-nERFVSDLLGKWRHNPGCFDKKTAIAHSLSESVD---GLVAGFGRSKNGIDFNAPDCEKANLVFLIGANprdLDIYLVMLAKLSKLLSEEFFRRELSSAVTHSEIISIIKR-- ->tr|A0A1J4V7K3|A0A1J4V7K3_9BACT Uncharacterized protein OS=Candidatus Hydrogenedentes bacterium CG1_02_42_14 GN=AUJ18_04070 PE=4 SV=1 ----LVAKAISLD-LPSDKNEAIKVAIKALTKNLSLe-eDEVFEAVMAREKALSTAIGLGVAIPHAKIKSIK---KFAYSIFCSEDPINFQAPDKTPVRIIVLLLSPenkMKEHVTLLAEISRRLKFSHVRQAILEAKTPKKVAEAFLQ-- ->tr|A0A1G3KSL9|A0A1G3KSL9_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_27_13 GN=A2Z98_13265 PE=4 SV=1 ----LSPERIMV-LEESNQKEMVEKLLTMIKGSPLIkn-fDTIKDAIWEREKIISTGIGLELAIPHTRREDIK---GFIASAVLVKKGVDWKAIDDKLVKFAILVCSPsdsHKQYLKLLAQTVLLWKDDYKRKKILESNDPFQIYNILKE-- ->tr|A0A0S8FG87|A0A0S8FG87_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium SG8_31 GN=AMJ59_09660 PE=4 SV=1 ----IEPSRVLRNVDARSKKHALDILSEMIAGAdDeLAQGAVFDSLISREKVGCTALPGGVAIPHGCIDGLE---RIIGAFVKLAHPVDYDTPDGVPVDLMFAIVLpdiAGTERKACLKEAGQIFGDPAFQRMLRSAKSSRTLYDMII--- ->tr|M1L379|M1L379_9PROT PTS system, nitrogen regulatory IIA component OS=Candidatus Kinetoplastibacterium desouzaii TCC079E GN=CDSE_0090 PE=4 SV=1 ----LPIDNILLEMSATSKKRAFENISLFFERKhDISSSAVFKSLLAREKIGSTYIGNNLAIPHGYVYDLK---KTIAAFVRLNRPIIFYNQNRQLVNTLMFFLVplnQAEEHIKILTKLTSNLLDKTTNKILQTED-KKIIYNTII--- ->tr|A0A1G0YQY1|A0A1G0YQY1_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_52_8 GN=A2X49_13160 PE=4 SV=1 ----LRQENLICGLRAASRDDALSQLCTLLAEKaGtpEEAKQWLTALLAREKIMPTVLSPGFAMPHARIANLK---NAMIAAASIPAGLDFNTKTPQPVKLLVLLLTpanDPQLHLKVIKDIAAAFIQRSAEEidAIAAIESP---SDLLA--- ->tr|A0A1V5QGE9|A0A1V5QGE9_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin345 GN=fruA_2 PE=4 SV=1 ----LKANTIRTDIGQLDKWTAIERLADLIVDSgKaTDRAALLDAILNREKQGSTGLGNGIAIPHARTDGVR---DVAVALGVSASGMDFDSADGKPCHLIFLIAAplhESTRYLEALAAVASLGERASLVAQLKSVRSVDDALAFFK--- ->tr|A0A1X4XV39|A0A1X4XV39_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfurella amilsii GN=DESAMIL20_948 PE=4 SV=1 ----NQIKDVDVNVVANDKYDLFQKISQSVALKvNVDSSIIYDLLKERELLGSTAIGNGFALPHLKLKDVK---SYIGVFV-LKAPIDFDSIDDITVSVIFVVLSpsdKPSLQLKTLTFLAKILKKSNVEHFLNK--SPQEIKDYLK--- ->tr|A0A229FVV2|A0A229FVV2_9BURK PTS sugar transporter subunit IIA OS=Polynucleobacter cosmopolitanus GN=AOC33_01325 PE=4 SV=1 ----ITPNNISLDIEVSSREELFIFIAQQFEKN-hgISANSVIACLEEREALGSTALGNGIAIPHGRVKFLE---QAHIGFVRLKESINFHATDKQPVKALVIMLVpeaATQAHLDILAKIAQTISNNKNKNILLTEPSADNIYQLLT--- ->tr|A0A1I0GHA5|A0A1I0GHA5_9FIRM PTS system, fructose-specific IIA component/PTS system, fructose-specific IIC component OS=[Clostridium] sphenoides JCM 1415 GN ----IKKEYIFTGMEFGSKDEALRSIAEQAVSLGLCRDveGTYQGFLERESQGPTGMEDGFAIPHTRC---ESVIQTGIIVMKSKNELEWESFDEKPVHIMIALIVpkenYGNEHIQILASLSRMLMKQEFRNRIMESDSAGEIYEIIH--- ->tr|A0A1V9CEJ0|A0A1V9CEJ0_9BACI PTS glucose transporter subunit IIA OS=Bacillus stratosphericus GN=B2I20_12940 PE=4 SV=1 ----FQKDHVFTQVNGRSKNEILQYISEKAEDLHITDDqsGLLTDLLKREDEVSTGLQQGFAIPHTKS---SAVQTASLLFLELEQPIDWGSFDDLPTSYLFTLLVpleeANVTHLKLLSGIATSLMEPAFIEKIQPGQTADYYYEVIE--- ->tr|A0A0H0YSM4|A0A0H0YSM4_LACCA PTS system, galactitol-specific enzyme II, A component OS=Lactobacillus casei GN=AAW28_08970 PE=4 SV=1 ----FEEAFIYPKLDAASYEDAVRKMSQNLLEKGYVTSEYPDQVLAREKNFPTGLVlanMNIGIPHTEA---EYVKKTAVAVATLKSPVKVHSMIDpeqELpVSMMFMIAVSdPKGQVTILRELMRLFQDQDLMEKIMSEDTASGIYKLLKA-- ->tr|A0A0R1F830|A0A0R1F830_LACCA Phosphotransferase system galacitol-specific IIA domain-containing protein OS=Lactobacillus casei DSM 20011 = JCM 1134 GN=FC13_ ----FSDRVITFDQTFSDRNTALKAVADQLLKAGAVVPTFEKAIIAREQTYPTGLQlndgIGVAIPHTDA---DQVIHDQIGFVSLKTPVEFRQMASatdVVsVNYLFVLALKtAHQQLDMLQKLMELFADDAEMTAFRKIKTADDFIHFMTE-- ->tr|S0S710|S0S710_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_01386 PE=4 SV=1 ----ENQKFLYYSFDEDDKETLLAKMSEVLIDAEFVHPSYQQAVIERERIFPTGLPtkgINVAIPHTDS---IHVKKEGFLVGVLEKPVTFEMMASkdvFLeVELIFMLAIKqPEDQLVMLQKLMLLCQDEQNLQLLKAKEKVVEVEQLLKT-- ->tr|A0A0Q6DM22|A0A0Q6DM22_9RHIZ Uncharacterized protein OS=Aureimonas sp. Leaf460 GN=ASG54_22145 PE=4 SV=1 ----LDRRAVLVGMPAADHGEAIDHLAARLQEIGRVHPSWGPAARTREETMPTGLPlgdLNAAIPHTDP---EHVVEAAVGLAILPEPVRFQSMDDpdtGLdVRIVFALAIKdKAEQIPLLQAVIEALSDEKRLARLAAARNPDEAFTALES-- ->tr|A0A180CNN6|A0A180CNN6_LACRH PTS glucose transporter subunit IIABC OS=Lactobacillus rhamnosus GN=PY66_05885 PE=4 SV=1 ----FNEEIMTLHSDAPDAATIITKLAHQLEAKDLVTEKFLPHVLAREEKYPTGLAagpIGVAIPHTDS---IYVKESQIAFASLAKPISFKNMVDleqDVpVLLVFMITMSsPHEQTALLSNLMNMFQDQQTLQQLNQSDTKKQVIDILNT-- ->tr|A0A1E5U458|A0A1E5U458_9STAP PTS sugar transporter subunit IIA OS=Staphylococcus succinus GN=AST12_10205 PE=4 SV=1 ----IDASNVILNLEARTSDAALSELAELMYSNGYVKSSYKDAVIAREKSFATGLPtvyCSVAIPHTDI---EHVEAKSIGVAVLKDTVPFVIMGEakeTTdVKLIFMLAMDkEDAQLSLLQKLMGIFQNDQLLKTIVNAKARNEIAQVIEQ-- ->tr|A0A1E5KZ28|A0A1E5KZ28_9ENTE Uncharacterized protein OS=Enterococcus rivorum GN=BCR26_02275 PE=4 SV=1 ----LNEELVDILTIEGDQEEYFEKVYEKLNQLDYIEDGYLDAIIEREKEYPTGLQtpfLAVAIPHTDP---EFIKKPFIYLVKLKSPITFGQMGTtdtKIqVDCTFVLGMEkGEEQLVILQSLMKMFSNEEVMNKLRTVNNERDFYQTVRF-- ->tr|A0A1M6JHC1|A0A1M6JHC1_9FIRM PTS system, galactitol-specific IIA component OS=Propionispora hippei DSM 15287 GN=SAMN02745170_02605 PE=4 SV=1 -----TAESIYYDaviLeDMNSKEEIISCLANYLQQKGYVNEQYQAATLERELEYPTGLPtkpIGVAVPHSKT---ENVIRPAIVMAISRKLVEFGEMGNagaSLqVGIVFMLALQgENRHLNFLKHIINFCKQESNVTRLYQVPAREEAYRIFQE-- ->tr|A0A1S2B5G7|A0A1S2B5G7_PLUGE PTS glucose transporter subunit IIA OS=Pluralibacter gergoviae GN=BB778_05630 PE=4 SV=1 ----FSPQRIVVFNDAISRTALLNELAQKLLDDGFVKPDFAAGVLEREDKYPTGIDmetHSVAIPHTEF---CYVNSTGFAIGINHAGVAFQRSDDpekSVePQIIVMMAIDqSCEKVIIIQSLFALLADPKKVEEICQK-PPEEIAKIFTE-- ->tr|A0A127F0X9|A0A127F0X9_9RHIZ PTS IIA-like nitrogen-regulatory protein PtsN OS=Rhodoplanes sp. Z2-YC6860 GN=RHPLAN_57030 PE=4 SV=1 ----LSIERVIPNLYAADKSDALRKLAAVAAtNSAtPA-DLVVSAVLDGAEMPAFGPGTGISLPHAFIPGLGD---PFVIFAKLNPPVDFGSTDGSKTDLVALLlspLDn-PRGHLQALACVARTLRDVHVRKLLRGAESRDSIYAVLCG-- ->tr|A0A0S8JPF6|A0A0S8JPF6_9BACT Uncharacterized protein OS=candidate division BRC1 bacterium SM23_51 GN=AMJ85_04620 PE=4 SV=1 ----MREDLICTDLVETSKETVLQALVDHLVdRGEvENGDEVVRLLMEREQLMTTGVRTDFAIPHAFSEHVHR---SVVALGYVRAGVDWQSLDQQPVRYVFLLlgpPQs-KGSHLRLLARLSRLLSSPAFVHHLAQAKSPGEMLEAVTA-- ->tr|E6W110|E6W110_DESIS Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Desulfurispirillum indicum (strain ATCC BAA-1389 / S5) ----LQQEHICTAVDATTRDELLRVAAQKINsVCAdLSAQTLFQALWEREELGSTALGSQVAIPHCKIEGLDQ---IRLFVFTSARGIDFGSPDGQPTSLFFVIlspPQr-VSEHLQVLARIARLTRSDGFVSDALAASDPVRILQCIEQ-- ->tr|A0A011RQV2|A0A011RQV2_9LACT PTS IIA-like nitrogen-regulatory protein PtsN OS=Alkalibacterium sp. AK22 GN=ADIAL_0241 PE=4 SV=1 ----SIYASVAVEVK-GSKKDVLQTVIeEVRDkSGSvFDASEVLKEVLEREALSTTGFGNGFAIPHGKSSDLSD---PLVAVVKLADPVEWEAMDDEQVDILIMLivpKEgg-AQSHLKLLSQLSYNLMDEEIQNYLRKAESNEDLVSVVSG-- ->tr|C5BSX5|C5BSX5_TERTT Nitrogen regulatory protein OS=Teredinibacter turnerae (strain ATCC 39867 / T7901) GN=TERTU_3823 PE=4 SV=1 ----LNAKRTRAKIAGGSKKRLIETLAGIFSeSDtGLDQTELFQHIFARERLGSTGIGGGIAIPHCRFNTEGA---TLCACVTLEEAIDFDAVDSKPVDLIFAMlvpENAEDEHLQTLAALAETLQRDDFVKRLRNCKTDEELFNVASG-- ->tr|A0A1E3GQS6|A0A1E3GQS6_9GAMM Nitrogen regulatory protein OS=Methylophaga muralis GN=ptsN PE=4 SV=1 ----VNADNISFHDEATSKKRVIENLSRMLAanTSAATAEKIFQVLLERERLGSTGLGKGVAIPHARVPDLTH---TVAAMLTLETPIDFESADSKPIDIAFGLlvpEDDTEHHLQHLSRLVTLFRDEDICSRIRQASSADAIFELLLS-- ->tr|A0A1F9MLI2|A0A1F9MLI2_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9 GN=A2511_17180 PE=4 SV=1 ----SGVLRVLPSLKAASKKDVLAELLEPVLaELGsIQASEVYQAIINRERLGATGIGQGAALPHALIAGFAN---HLAVCGRSGAGVSFDAADGKPIHFFLLYlapIGa-GTTYLHCLAMLAGFLRSAHVQARLLAVRDAKAIQAILDE-- ->tr|A0A1B3BCH0|A0A1B3BCH0_9GAMM Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Kangiella sediminilitoris GN=KS2013_1797 PE=4 SV=1 ----LAPERCQLGLQASSRKKALQVLANIFSqSCEsLDSFEILQALTEREQVGTTAIGNGIALPHGRLSNCEK---PIAILATLDTPVDFFASDKENIDVMFALlipKDl-DFRDLAGIEQVKTIFDNKTFCAQIRNAHNNEALFDIIEQ-- ->tr|A0A1F2QBT7|A0A1F2QBT7_9BACT Uncharacterized protein OS=Acidobacteria bacterium RBG_13_68_16 GN=A2Y78_12225 PE=4 SV=1 ----LKPEHVFLDIPAHTREEVLVYVAQRLEqAGAvQRSQDLVDLLLDRERLGATVVGDQTAIPHCKVPGLAR---VVAAFARALEPVAFDLDA-GFARLFFFIfspAEq-PSAHLQVLSSIARVLGDPNVRSAFEGASDANALTAALSR-- ->tr|A0A1T0AWK2|A0A1T0AWK2_9PAST PTS IIA-like nitrogen-regulatory protein PtsN OS=[Haemophilus] felis GN=B0188_09425 PE=4 SV=1 ----LTPGQIRHGVICSSKKRLFEIIAEIVSdYLHegDHTQCCFECLLTREKLGNSSLGNGIAMPKAKIPLGEK---PIAVFLQLTEAVEYESSDNREIDLVFALlipEKv-CADYVPHLAEMIEQLQDKNLCKQLRQAQSVEEIWRLFEH-- ->tr|A0A1V5PEH6|A0A1V5PEH6_9BACT PTS system fructose-specific EIIABC component OS=bacterium ADurb.Bin363 GN=fruA PE=4 SV=1 ----IKSENIFLDVKGKTKYDIIRNMINSSTiEEGlK--EYAYEKVKEREELQPTSVGNGIGIAHAKIEKIKE---LDILVGVLKKGVDYDAYDDKPVNIIFVIlspVEn-NREYLSVLSKISRFCRKENMIENIIQENNREYIIDLFSQ-- ->tr|A0A1W9M7E8|A0A1W9M7E8_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium IS3 GN=BWK80_41140 PE=4 SV=1 ----LRPENIFLNAELPDKDAVLRFVADACVrNRIvSEGDALYNGLRQREQSMSTGIGDGIAFPHSTHPEAAD---AAVLLIRPSKPLEFESIDSLPVGIILAIvipEHq-TALHLQILGGIARLCKNREILRTIREARDSESLWEFIRN-- ->tr|A0A1V5VBF3|A0A1V5VBF3_9BACT PTS system fructose-specific EIIABC component OS=Lentisphaerae bacterium ADurb.Bin242 GN=fruA_1 PE=4 SV=1 ----LSPERILILKGRLSKKEVLLAMIGTLAg--EyCDRDDLEWGIFHRESLMSTGIGSGIAIPHISLPNVEE---TRVAMALCPDgIADYQSQDSQPVRLVFMIvagKNq-KPPLLKVLAAIGTLFYDGRLKAAFLAAHDPKTCMEILIR-- ->tr|A0A235HB43|A0A235HB43_AZOBR Transcriptional regulator OS=Azospirillum brasilense GN=CHT98_18920 PE=4 SV=1 ----LSAHNVILDAGPANKETLLDLLATEAAsRIGTPKEDILKALQAREHIGSTALGKGVALPHTELRGTES---PLVLFARLRRPIDFEARDDEPVDLFFLVlwpTATRKGLLPVMGEICQALRDPQSLRKLRQAETPDAVVQLVRQ-- ->tr|A0A1Z9BLX6|A0A1Z9BLX6_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium TMED105 GN=CBC65_03485 PE=4 SV=1 ----LSPDFIVMHPKVSSKKELFEQLLEALKpQCtSeAQFDAASEAVWARENVMSTAVGFGFALPHGKTHEVSQ---HMGVFGVLAEPLDYDGDNKEQVQLVFLLvgpKQe-SANHIKLLSQVSKLMNKEVLRQEILRASTAQEVYGLLKE-- ->tr|A0A1H4MN36|A0A1H4MN36_9ACTN PTS system IIA component, L-Asc family OS=Atopobium minutum GN=SAMN04489746_1149 PE=4 SV=1 ------------KEEADDWKEAVRHACAPLVAHGSVPCEYSDEVVKSVEeLGPYiFLAPHIAMPHVQL---DGKTDLDVAVLKLNHPVVYDDN--HEAQLFVAFSARDGqSHIEMIQELATFLIKEKNVDALLKAKCESDIYQYIKTN- ->tr|R7G8I1|R7G8I1_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Eubacterium dolichum CAG:375 GN=BN631_00350 PE=4 SV=1 --YKFIPELVETNISAKNKEEVIRFLAKKLADRKCVSSHYSELVLQREKEYPTGLitkGAVIAIPHAFDP---ETKGNNIAIGILKTPVGFKHMEDideTVpVKIVFMLAINgSHEHMEMLKILMQLVRDEELFKKLQSISSKNEICKLLN--- ->tr|A0A0K8JD04|A0A0K8JD04_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_1470 PE=4 SV=1 --SLLTLESIHIGMPQQDRYEVLKVLSDSLKEQGFVTDGHYDALLKREMHFPTGIpagQFGIAIPHTDPA---YVRQAAIAVGILAHPVVFYQMGAettEVeVQMVFLLALTqANKQINMLQNITRLIRDGEALAFIRHSTSREEIRNKLQ--- ->tr|A0A1S8NS17|A0A1S8NS17_CLOBE Mannitol-specific phosphotransferase enzyme IIA component OS=Clostridium beijerinckii GN=mtlF_2 PE=4 SV=1 --DLVKDELIDIAQEDLEYKEVISYLGNLLLKNNYIKEDYIKDVLLREEIFPTGLelkNMGIAIPHANPD---NVLKNGIAILKLKNPVRFSNMETgdDVyVNIVFMLALKnPDDHLKMLQSLFLMFQKEEVMDELGKVQSEEYIKIIML--- ->tr|N9WNX1|N9WNX1_CLOIN PTS system, fructose subfamily, IIA component OS=[Clostridium] innocuum 2959 GN=HMPREF1094_01657 PE=4 SV=1 -----TEQHIILDMEGNTQKEILHALAEIAFREGKVSdaDTFFQELCKREQECTTGFGKGIAIPHARH---ACIKEAGILFVRMKHKIEWKSIDEKPVEAAVCLLAPddkHDFHLKALSKLARRLMHEDFVDILKTAEKQ-QILSEIID-- ->tr|A0A1G4FMQ5|A0A1G4FMQ5_9FIRM Multiphosphoryl transfer protein 1 OS=Sporanaerobacter sp. PP17-6a GN=fryA_2 PE=4 SV=1 -----KKDYIFLDIGLKDKENSIDFIAGKAVELSISNdkDQTKKDLWSRERAFNTAIDETIAIPHTKS---ESINLPAIFIIKSKNIIDWG---GKNIKLIISFLTPkenkDNIHLTMLSKISRKLVDDKFKTTLNESDDINLIYELIMS-- ->tr|U2Q4U1|U2Q4U1_9CLOT MtlR family PTS modulated transcriptional regulator OS=Clostridium intestinale URNW GN=CINTURNW_2638 PE=4 SV=1 -------EFIELNAEYNTKEELIRSIRKKLKEANYVSDGFEESILMREERFTTEVGSGVAVPHGAF---DYVNTPIMIYIKLKEAIKWKE-E--LVDKVLLFCAREKDtakFIKFFRNFYNVIETEDEKRKLESFRDKRELKSYLED-- ->tr|A0A109MS40|A0A109MS40_9BACI Uncharacterized protein OS=Bacillus simplex GN=AS888_03210 PE=4 SV=1 -------DLIFLQMELSSPEEVIESICQTIITKQLASPDITKLVIEREMASPTSYGNLIAIPHPLK---HISYETFLAFCTLKKPIKWGNE---MVQLICFFNIKKNNemdLQVLYEFLYTMINDKNIVEKLTNCRTVPEFSALLYS-- ->tr|A0A101E4V7|A0A101E4V7_9THEO PTS modulated transcriptional regulator, MtlR family OS=Caldanaerobacter subterraneus GN=XD49_1301 PE=4 SV=1 -------DLSIFQVKVKSKGEIILKLSEKLKEKGYVKDGFYESVIERESFSSTAIGNYVAIPHPYS---GFVAVPKIAVAVLDAPIKWDEAK--KVQLIFLIALDLSVredFKMIFEELSDVVENESKVQKLLKCRSFEEFVRIFRA-- ->tr|G3K4I1|G3K4I1_9LIST Putative PTS regulation protein OS=Listeria fleischmannii subsp. fleischmannii LU2006-1 PE=4 SV=1 -------KYFTILEGKRTKEQILTTLANKFEVEGNVQASFLKSVKERENIVATYLGNGLAAPHPIS---ADVKETKIAVCITKEPIIWNEEG-DEVQIILMLAVKNKEqeqLSTVYEIISQIVEIPKLAKEIREVEDFEAFIRILEY-- ->tr|F5WR13|F5WR13_ERYRF PTS modulated transcriptional regulator OS=Erysipelothrix rhusiopathiae (strain Fujisawa) GN=ERH_0136 PE=4 SV=1 -------KLFIANPDTQSPQELLELMSQKALNLGYIDKACQESIIEREVLGSTEVGNLVCIPHNIE---GSVYRPSIVVCVLDKPIPWKY-D--HVQLILMILIDQDHrthCSDLFAELYAEIDHQYKVSNIIKNKNIAYMKSLFIE-- ->tr|H3NM72|H3NM72_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_00433 PE=4 SV=1 -------ENIYPLLDFNKPKELLKFICNDLVLRSQVNKGIYESIIEREKISSSSIGNLIAIPHPLN---KMSEKTFWTIITLKDEIRWGD-N--NVRFVILLNVVNEDkmyLDTMYENLLKLINNKTYIDELLEINDSKIFYNRIKE-- ->tr|R9BZ94|R9BZ94_9BACI Transcriptional antiterminator OS=Bacillus nealsonii AAU1 GN=A499_19803 PE=4 SV=1 -------DLVQLEIDKDHPYEVIEMLGNLLFQKGLIEKEFIHSALNRERKSATAIGGNIAIPHGDP---EMVIQSAIAVAILKEPIQWGN-E--YAAVIFLLAISKQEqnlNRAVIGQIASYSENLEFSRRIAKLTDVKSVLDYIQ--- ->tr|A0A0B4S4B1|A0A0B4S4B1_9BACI Transcription antiterminator OS=Bacillus sp. WP8 GN=QR42_01365 PE=4 SV=1 -------RLTLMNADLSSKDEVLNILCSRLEAHQLVSSSFRPSVLEREQMSSTYLGSGIAMPHPLI---TNEGTSSVAIAHLKQPIDWQG-D--QVSIVFLLAIHKDDaacMNQFFEQAVDLLDNPDRIRALKQAKTFDELMDAFFQ-- ->tr|A0A0R1MGL0|A0A0R1MGL0_9LACO Uncharacterized protein OS=Lactobacillus capillatus DSM 19910 GN=FC81_GL001785 PE=4 SV=1 -------KHIFIQQKFSNKREVLHFLSNQLISQHLVEKDYENLLLQRESFASTYFGNLTAIPHPVH---MVTKKTFWTICTLERPLTWDKAG-HQVQFICLMNIKKGEknnLEQMYQRLLAFLEDKELVRKVVKANTKSEVIKLLGE-- ->tr|I7KLE5|I7KLE5_9STAP Uncharacterized protein OS=Staphylococcus equorum subsp. equorum Mu2 GN=SEQMU2_13600 PE=4 SV=1 ---------------------------------------------------------------------------------------MGD-K--DVQLVFYLGLKSQTtvdMEPIFKRISHIINDFSLVVELLNQSNEKDLKETYFD-- ->tr|A0A1B7KS79|A0A1B7KS79_GEOTM Uncharacterized protein OS=Geobacillus thermoglucosidasius GN=A7K69_08430 PE=4 SV=1 -------ELFFPEIDKKDPIDIIKSMTYILNIKGYVDDSFLDSVLEREEISPTSIGNLVAIPHPVK---PNALNSCVAIGIMKKPVKWGEH---HVQLVLLLALNEKDkdkYSDLFNQLWLLVQDKKLVADLCKSSDFAQFIKRLEK-- ->tr|A0A1D8GCK1|A0A1D8GCK1_9CLOT Uncharacterized protein OS=Geosporobacter ferrireducens GN=Gferi_02855 PE=4 SV=1 -------QFFYLKDTFENEFEAISFMAEKLQEAKIVPANYKALVIERELIASTSFGNLVALPHAVE---LNAFQTVFSVAILKKPMRWGT-H--KVQLILMSAVKRGErkmLNELINHIAAILDDSKAVNNLVMSSNFDSFKHNITR-- ->tr|A0A1F9ZPM1|A0A1F9ZPM1_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_03765 PE=4 SV=1 -------EDIHLMVDLKTKEDILSFMARHLSAKNHVTEDYLDSLWEREAMGPTVISSLIAIPHGTF---ETVLRSTVQVVTLAHPVLWDD-E--HEVRLILNVAStKEEasdYIPFFTHLADHSEDLDLWNRICAMRNKEDLAQALSE-- ->tr|A0A1E5H9I7|A0A1E5H9I7_9ENTE Uncharacterized protein OS=Enterococcus ureilyticus GN=BCR24_06980 PE=4 SV=1 -------EHFKRNIYLNSPSLYIEHLGRQLVEADYIDPHFIELIKDREKMSATSFNNSVALPHAIE---MSAKKTGIAIVLNDRPIKWEN-Q--DVQVIIMIVMNQKDmkkFRQLFDFMIDTFSNRAKLNRLLNVTHYEGFIEELFT-- ->tr|A0A109UHE4|A0A109UHE4_9FIRM Uncharacterized protein OS=Erysipelothrix larvae GN=AOC36_08310 PE=4 SV=1 -------SISVFDEKVQDQNDAISILSNIMFKQGFVDHEYRDSCLLREELSSTFIGNMVAIPHAYH---GHVLNQGIGLLVSKKPFDWNG-A--KVQLVFALAIDLKSsqdFGDIANEIITLVNQVDVLDKLFQTKDLRSFKKFIK--- ->tr|A0A1M4SPV4|A0A1M4SPV4_9FIRM Transcriptional antiterminator OS=Alkalibacter saccharofermentans DSM 14828 GN=SAMN02746064_00334 PE=4 SV=1 ------------------------VLQPSDDDKGYAAEGFIESILIREKKSSTYIGKGLAIPHSKT---EFVKKSKIAVIRLKRLMVYKH-E--MIDTIFILCIKMEGydmAANVFGQFYEMLDDDSQIAELKKAYTPQKINEVLRR-- ->tr|A0A1T5J7E7|A0A1T5J7E7_9CLOT Lichenan operon transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_00973 PE=4 SV=1 -------ELFFTDIQFESKEKVLDFLTSQMVDKGYIGKDIKKSILDREKLSSTAIGNLVAIPHALQ---VVEVPSCVCIGILDKPIVWDQNK--KVQLVMVLSISKNIsyrFTDMFGTLYQVTKSPLSVEELINQNDFDKFHIKFLS-- ->tr|A0A1T5KCP2|A0A1T5KCP2_9CLOT Lichenan operon transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_01687 PE=4 SV=1 -------ELFMISEEADTKDEIINIVANNLKDKKYAGDDFLPKVYERENVSSTALSEMVAIPHPVR---ACALKTGIAVCINKKGVCWDETK--KVHIMLMLAIKPKEykyMDGIFDLIVKILENDCITMKLLNCKSYEEFLKELKD-- ->tr|A0A1T4PYR0|A0A1T4PYR0_9BACT Transcriptional antiterminator OS=Anaerorhabdus furcosa GN=SAMN02745191_2227 PE=4 SV=1 ----------ILKCDYTNQEILFEEVEKKLKSKHYIEEGFKEDLKHRESKCSTSIGAYTAIPHANP---QFVKKSVICVVTLQKPMNWGS-E--EVDVFFFLAITKSDfssINIKLRNLYKLLYSETFHKQLLDAEKQDQVLKLVDI-- ->tr|A0A242HNS0|A0A242HNS0_9ENTE Uncharacterized protein OS=Enterococcus sp. 12E11_DIV0728 GN=A5865_001256 PE=4 SV=1 -------CVLLPNQSLSTPREIIDVFCTALSERVSLPDDFTDQVERRETLSTTEVGNQVALPHPCE---YDGEKNLLAVMSLKKPVRWKY-N--NVRLVILQAIPPYEnndAIQFQEDVTRLVCDQKAVTRLVRNLNFDTLQFELFG-- ->tr|A0A010Z078|A0A010Z078_9CLOT PTS system protein IIC component, Fru family OS=Clostridium sp. ASBs410 GN=K413DRAFT_2695 PE=4 SV=1 -------KLIKVNMQAGDKNAAIEELAELLYKEHVLKdkAIYIQNVLEREAQVPTNLENGVALPHGKSD---AVLRPAVAIGISKRGIRFEEG-SPVSHIIFLIAMPnnaDDTHITLLSGITSRLLDCDCLDYLKEAKRPEDILAALST-- ->tr|A0A0U3ECB8|A0A0U3ECB8_9MOLU Uncharacterized protein OS=Mycoplasma sp. (ex Biomphalaria glabrata) GN=ASO20_02945 PE=4 SV=1 -------HVIRI--DVSSQNELFEKIADNLHEHQVfSCdkNIIINAYKEREEQGTTNLGEGFAFPHILIN---KIKVPTILIVQLENEIMYGDSNIDLAI---VLAFPktmeGGEHLRVISKYSEKLLDEKFLKNLRKAKPAQLKKELTDF-- ->tr|I9DN41|I9DN41_9FIRM Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Pelosinus fermentans JBW45 GN=JBW_02581 PE=4 SV=1 -------SLIELHMKSKSKTEIIETLAHKAKELGYISEveGYLQDVFALDESSPISFGYGIAIPYGKSR---YVLTPFIAFARSEEAFTWDHRVDHEARLIFLIGvpeeQDDDFDVKMLTHMIGGLTNESFRRRLLQTSDAAEVVELFKE-- ->tr|A0A1L8REV5|A0A1L8REV5_ENTAV Uncharacterized protein OS=Enterococcus avium GN=RU95_GL002651 PE=4 SV=1 ---------------------------DQLIKNEQERSNYKDEINESlEQFGPYYLl-PNVILFHGKPDK--K-YSNALVIVKLNKAFTAVED-NLPVKLIVGMTAEdSNAHLKVLQHLVEKLNVYQNVVDILSAKKKEEIEKVIH--- ->tr|A0A1F9ZRT5|A0A1F9ZRT5_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_06395 PE=4 SV=1 -------KLILTGLNHLDRNEILNLACDRLESLGRVKSGFRKSVFHREQTIPTCLGNGIAIPHGKEE---FVLTSSIMILCCDHDVDWGNGSARLMFLIAVNFTGETDTKEVLTDLYNVIDTPMLIQQLKNARNADEVLALFA--- ->tr|A0A1M6K9T5|A0A1M6K9T5_9CLOT Transcriptional antiterminator OS=Clostridium caminithermale DSM 15212 GN=SAMN02745912_00341 PE=4 SV=1 -------EIFYRSKKFKHPNQIIIEMCENLEKKQYVKREFMESTLAREKIMATEVGNGIAIPHGDPK---EVIKSCIALTILENPLKWKKEMVKYVFLICIAEKDVAKTKTIFRNLYRSMDKPEFLNGLKKNRKFVKrMLDQLE--- ->tr|A0A1L6AFW0|A0A1L6AFW0_BORGR PTS fructose transporter subunit IIA OS=Borreliella garinii GN=BLA33_02260 PE=4 SV=1 ------KDLVFILPEANSKEDVIDFLVEKVNDKGYIDskKEFLQGILDREKIGDTSWENGVAIPHFIGDV---VKTSFISLLYIkGTGVKWS-EENPPVNLIFLICMSkkqqGNEHIKSIAFIAKLFEDDAFKNALSGIVTADDIYYYMEN-- ->tr|D1ARV2|D1ARV2_SEBTE PTS modulated transcriptional regulator, MtlR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3754 PE ----LPKENIKVVNSVKNWQEAMEISGRILVDNGYTEWEYVESVIDMVYKHGTYmvLKKNFILGHGNY--LEKVRKAGLSFLYIKEGVEFPENH--FINCVITLCSRDkKEHTFGLLELHRVIENCDLYKKISEKNSGDEVYREI---- ->tr|H1PQP4|H1PQP4_9FUSO Uncharacterized protein OS=Fusobacterium ulcerans 12-1B GN=HMPREF0402_00737 PE=4 SV=1 ----ISMSRIEKREKADSWEEAIKMSGEKLLHENIVSEGYLDEIIDLINKFGSYmvIQEGIILSHARG--NESVSKTGISILLLDEPVEFPENE--KVKLLITLASKDkREHLNGLMEFINTLREVKLLDTLENCQTISEIYITF---- ->tr|D1AHU1|D1AHU1_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_1463 PE=4 SV=1 ----LKEENIIFEkKKLEKWEDAVKEGFKPLEKGKYVDESYYKSIIELINNFGSYmvVSEGLAIPHAEN--MNNVHKSGISLLYLKHPVIFPGNK--KVNLLFCLSAVDkKDHVQSLEDIIRLEEEFSFRKKMAETNSKEEITEIL---- ->tr|D1AHL2|D1AHL2_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_1382 PE=4 SV=1 ----LGKENIYTNLTFDSWENALYFGGEVLEQKGAVSPDYVESIINILKTHGSYmvINEHILLAHGRN--EDNVFETSMILMTLKDYIEFPNDK--KIKIIILFSSRDnQEHLNALLKLTELLDERDLYNQIKDLETSGEIYEKI---- ->tr|C6JIT2|C6JIT2_FUSVA PRD domain protein OS=Fusobacterium varium ATCC 27725 GN=FVAG_01233 PE=4 SV=1 ----LSEKRIKLKGKAIDWRGAIREAGELLLRDECIEEEYIENMIKLVDDFGNYimLIPNVIFPHTKS--KDLVKKTAFSIVTYDKRIDFLDEG--KIGIVICFCVKDeREHLDSLIEIVEKIEENNLEEKIRKSKTAKDVIKYL---- ->tr|A0A1E9JK47|A0A1E9JK47_9FUSO Uncharacterized protein OS=Fusobacterium sp. HMSC073F01 GN=HMPREF2747_07540 PE=4 SV=1 ----LKKENILLNEKIIEWKKVIKKGMEILIKNGSVNHDYEKKLLYSVERYGSYltIYSNVCFAYSKD--KSEVRKSDVVFIELEKSINFPGNE--SINKVFVVSAINeREYLIIAENILDILTEGRLEDIINKKIK------------ ->tr|A0A0X8KAZ7|A0A0X8KAZ7_9FIRM PTS ascorbate transporter subunit IIA OS=Selenomonas sp. oral taxon 136 GN=AXE86_06280 PE=4 SV=1 ------EDLVLFDVEAADREELLTKLANVLREKGYVKDSYPQAILEREAAYPTGLntkGVAIAMPHAAAA---HAVEAAILVARLKHPVTFKEmggtGKDVPARLVFMLSIDDpEGHVIMLGKFMSIFCDEGKLVDLYETNDPKAVVEKLSK-- ->tr|A0A174HFV7|A0A174HFV7_9FIRM PTS system galactitol-specific transporter subunit IIA OS=Faecalicatena contorta GN=ERS852491_03134 PE=4 SV=1 ------KEMILTGIKARNAEDIMRRLCDRAMQMNCIEPVFVTALLEREKEYPTGLptGVPIAIPHIHDG----CLRSFFSMAVLDTPVAFGCmgdpDETVETRLVFLFGITDpSYQTAVLRKFSNIFQDDGIMNELLEIDKPEAMIQKMKE-- ->tr|A0A224WY92|A0A224WY92_9LACT Uncharacterized protein OS=Lactococcus sp. Rs-Y01 GN=RsY01_701 PE=4 SV=1 ------------DKQYLNKNQALEEISRNLIHNGFVSDEFVQDILERENDPdiSTDLPTGVSIPHGNPA---FVNKTGIFFIRNHKPIFWGKHAVKMI-IVLCIAQKDHHKINgILSDLYSIVESKKAIEMIYQFKNIDDFSSL---S- ->tr|A0A099IBH3|A0A099IBH3_CLOIN Uncharacterized protein OS=Clostridium innocuum GN=CIAN88_02695 PE=4 SV=1 ---------CILLKKDvQSKEDALHMLADCLNEEAYITDssAFLKDIHKREEEFCTYVGHETAIPHAIS---ACVSKAGIAFLRSDKAFQYGSSDET-VKLLfmLAIPKDsNEQHLRMLSALATKLMHKEFREQLLHAKSISDVYEILML-- ->tr|I4B5D2|I4B5D2_TURPD PTS system IIA component, Fru family OS=Turneriella parva (strain ATCC BAA-1111 / DSM 21527 / NCTC 11395 / H) GN=Turpa_1842 PE= -----TEANihiisaqNPGNFDlt--DKWTLLNGLRKALCER--eqvsaeLCAEIEHELLAREKLMSTGIGEQMAIPHAVIAGACKLM---TQCAILPEGIEFESIDGSKAHIVVMLVApksALQAHLKVMASIAKVFYRAEARAKVIASKTPAEALAAIMS-- ->tr|A0A1V6G051|A0A1V6G051_9BACT PTS system fructose-specific EIIABC component OS=Planctomycetes bacterium ADurb.Bin069 GN=fruA_4 PE=4 SV=1 -----SPERIVWLSSc--DRGEVLSELARLHTSFDTtiALEEVRRALVEREQLNSTGIGQGLALPHARIPKVQDFS---VILGLHKGGIDFNSFDGEPVHLFLLIIGpttANDRYIQILARASRFLRAKAA--DILAAATADEIYAMTLD-- ->tr|A0A1V5XZZ2|A0A1V5XZZ2_9BACT Mannitol-specific phosphotransferase enzyme IIA component OS=candidate division BRC1 bacterium ADurb.Bin183 GN=mtlF PE=4 SV=1 -----AEGVILCPLEet--EKWAAIEECVQALPHV--asrkiDFASAMAAIREREAQeHSTILDNGVAIPHGILPDPAPLA---GALGVSPVGVSYGV-GARKAGLIFVIVGsrsVRREYLGILAQIARLFRGLDLKNKIMQAKLPGDVLQLIRD-- ->tr|A0A1V5YUN8|A0A1V5YUN8_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Hydrogenedentes bacterium ADurb.Bin170 GN=fruA_2 PE=4 SV=1 -----EASQIRIIPAGATKHEALEILVEALCqNPAIQNKEVfTRAVHEREAIQTTGLGNGVAVPHVRIDEVSAPT---VALGIAPDGLDFQALDNRPVYIIVLFatpQDSGKTYLSLLAKVMVTLREEETFAALAACRTVEEVTSLLGI-- ->tr|A0A1V6G7I8|A0A1V6G7I8_9BACT PTS system fructose-specific EIIABC component OS=Planctomycetes bacterium ADurb.Bin069 GN=fruA_1 PE=4 SV=1 -----TDDLILADMKARDKRTAINEIVAFMCaRNGISEenaRKVEAAVLRREGRGTTGIGKGVAIPHAKNCgQVDEIV---AAFGVARGGVPFAALDGEPVRLVFLVvspRGLENDHLRVMRKIAHLARDDKTNRFLATTRDFSTLRAILDE-- ->tr|A0A1U9NLA8|A0A1U9NLA8_9BACT EIIABC-Fru OS=Phycisphaerae bacterium ST-NAGAB-D1 GN=fruA_1 PE=4 SV=1 -----VDKACIGFMDKCSKQAALNSLVDLIGkSKDVSDvDEVRTAIFHRETLMSTGIGLGLAFPHARLSSVKKPA---MAVGLCREGIdDYESLDNAAVHLVFMIvagKDQHAQYLRLLASISKKLKVENVRKSLINAPDEDSFYALLKE-- ->tr|A0A1Z8ZQW2|A0A1Z8ZQW2_9BACT Uncharacterized protein OS=Verrucomicrobiaceae bacterium TMED86 GN=CBC46_11400 PE=4 SV=1 -----SPECIILQLDKTEHEEVVLEMIGHLAeigkIASKDCYRYSQAVMERESQTGTGLGAGIAIPHARVPGLKEEV---AVYGRSEEGVDFESPDQGLAHHVCLLlvpEDGASNHLKILRELAKVFSQADLRKKIRSAQSAEEISELLCI-- ->tr|F4PFZ3|F4PFZ3_BATDJ Putative uncharacterized protein OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_93283 PE=4 SV=1 ----LTEDMIHFTSESLDWHHAISMAAKPLVNAESVEERYVDAMIKNVEEIGTYihVGKGIAIPHARPE--EGVNKIGELGVTGvevSHSDLSSATPQDADVFFLAKDIAEGgSHLGEVVVLDSIIDMDELRTKVKQVLEEKNLI------- ->tr|A0A161YB42|A0A161YB42_9ACTN PTS fructose transporter subunit IIA OS=Propionibacterium avidum GN=A2U93_08065 PE=4 SV=1 -------ELTNVNAEAADRDQVLTAMAHQLDESGVTNAGFLEALLKREENYPTGLpiSGGVAIPHTDPQYVTrdavavTTLRTPVLFGQMG-----GSeEDEVSVSVVILMALSNaDDHLSMLQNIVKSIQNGDLMQRIRsA-TKPEEiv--SIV---- ->tr|M4ZC53|M4ZC53_STREQ Putative PTS system, galactitol-specific IIA component OS=Streptococcus dysgalactiae subsp. equisimilis RE378 GN=GGS_0293 PE=4 -------EVVCLqVDNIKNAEQALAYLGNQLVATGAVKDSYVKAVIDREAIFPTGLqfeDYGVAIPHTDSEHVNhtqlalMTLTEPVSFTQMA-----TNDQPVSVRLIIMLAIKDsHEQVDMLQKLITLLQNPDVVHDLLaYGPDQKEsvlqLLSRH---- ->tr|D1AWN1|D1AWN1_STRM9 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10 -------KVFFENLEVSNKNELFEFIVENLVKLERIEKPqrILQKFHEKESELTTFLGSKFAIPHLKS---TKVLENTIVFIRLKNPLIWNEEGD-MAKYICAVLVKPrydDLYIDILMSLSRNIIDSNKANILKHSENKEEVLMLLN--- ->tr|A0A0E3UUA7|A0A0E3UUA7_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_00745 PE=4 SV=1 -------DTTLIDIDIKDKIDLFTKITKISKEKGYISDEqgVIEDFYAKEQNTETYLGTECAIPHARS---SRILKNVIFFVRVKNSIKWSDED--NAKFIFAILAKEndvDKHIDMLMAVSKKVLDPKVLDVLRKSNSREEILDILC--- ->tr|D1AVN5|D1AVN5_STRM9 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 10 -------DNIIINSNKINKENIIENMISSL--NLDIEISenIKNEIMIREKIDNTVLGFGFAIPHCKS---KYINESKVVYLKSLTNIIWDKEEE-PVNHVFMILVPEnnvGEHIDILKDISSKIIDKNFRNKLNILEDKIEIEKILN--- ->tr|I8IZ25|I8IZ25_9BACI Pts modulated transcriptional regulator, mtlr family protein OS=Fictibacillus macauensis ZFHKF-1 GN=A374_13655 PE=4 SV=1 -------TLVFIESKPCTRESIIKEQATAMQQQGYVMEGYLESVLQREQQSSTAAGGEIAIPHGNPS---FVFRTVLAITVMRTPMQWGTTS---VSLVMQLAARKEDHhqlQALFKEIFQLTENLQWIRTLQQAEDTKALYALF---- ->tr|A0A1I6U8S4|A0A1I6U8S4_9BACL Activator of the mannose operon, transcriptional antiterminator OS=Marininema halotolerans GN=SAMN05444972_11457 PE=4 SV=1 -------ERLFLQLENMERDQVLRLLADALVQAGFVDHAYVESVLKREHLSSTAIGGGVAIPHGALH---HIHHPGIAVATLKEPIQWEGEP---IHTIFLLALLPEERdrsQRIFRELVDLSADAARLDKLQTLQNPYMWIQQL---- ->tr|A0A0R2ILJ7|A0A0R2ILJ7_9LACO LicABCH operon regulator OS=Pediococcus cellicola GN=IV80_GL001815 PE=4 SV=1 -----NSQLIFFAKKTETRAAVIKNIGKQLQKLGYGKNGIIEAALNREKLASTAID-NIAMPHAPIE---FVLKPCIAIYINPQGIMWEGNK---VNIVFFLAMNreVQNKIEQIYKrFNDILENKKLLKELVGCTNAQVVLKKLGS-- ->tr|A0A0R2CYD2|A0A0R2CYD2_9LACO PRD domain protein OS=Lactobacillus rennini DSM 20253 GN=FC24_GL001921 PE=4 SV=1 -----RPDLVFKVAAAGGYRQVITKIAHQLFVNGYITdqEKVIQAAISREKLASTALD-QFALPHVSPN---LIKRPAIVLLVSQQPINWLGDqQ---VHFVFFMALNstVHQSLREIYRlINQIIDDHQLAKRLLQVEKAPQLIQVLND-- ->tr|S2PHP1|S2PHP1_LACPA Sorbitol operon transcription regulator OS=Lactobacillus paracasei subsp. paracasei Lpp123 GN=Lpp123_09916 PE=4 SV=1 -----SPTRILVSSKHLERDDAIKMIGQLLVDRDLAKIGVAESAIAREEVASTLIRQdQVAMPHAQSE---YIKKSGITLLVATHGVTWGDGE---AKFVFFIGLNqhAikNTNLDAVYHrFNQLVSSDDALSLLAKANNPKAIWHQLID-- ->tr|C2K0D8|C2K0D8_LACRH HTH domain protein OS=Lactobacillus rhamnosus LMS2-1 GN=HMPREF0539_2623 PE=4 SV=1 -----EPALIVPNLPSTDRETALSTLIQRLTQAGVFEdaSLPLKLAEDREKLATTAMG-LVAMPHISPE---MVRRPAIALGLAPDGLDWAGQK---VKVIFFLAVTatVPGDQRGIYQvINRLIDDQRFCEVLAQSQSTTEAVKALAE-- ->tr|A0A0R2E0N3|A0A0R2E0N3_9LACO LicABCH operon regulator OS=Lactobacillus mali KCTC 3596 = DSM 20444 GN=FD00_GL000666 PE=4 SV=1 -----SLNQIYVNEQLSNANQVISFLGKELINKEFAKSGVIESALEREEISSTVIK-NMAVPHSKVK---YIIKPSISILLNKNGIEWGNKK---VYLVFFIGLNnsVIEKSKEIYKyFSKLIYPE-FIKKACKCNSSEEIYELIMR-- ->tr|A0A0F4LLC3|A0A0F4LLC3_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_04320 PE=4 SV=1 -----SPETIFIGNL-SSQKDVIKYLGNKLIELGYADPEIIGSINSREKMASTALAKlNIAIPHPEPG---TVRKTNIAIYIPKHEIKWGKSK---VNLIFLMSYKkaDinVLPFDDIYHgFNLMVSSDELRVKLLSSKTKQEAYKSIYQ-- ->tr|K9ICZ1|K9ICZ1_9LACO PTS system transporter subunit IIAB OS=Pediococcus lolii NGRI 0510Q GN=PLO_1788 PE=4 SV=1 -----DTQLIQIDSVKKSYVTVLEEIVGSLTKQNILVnnPKILEMLVEREKMASTALN-AVAIPHIAPN---YVQKSAIALWLVPQGVQWLGNT---VYVVIFLALTreQVAASREVYKiLNRMVENTAFCQQLAQVATVSKAMEHIQK-- ->tr|F6IUV1|F6IUV1_LACPE Transcription regulator, mannitol operon OS=Lactobacillus pentosus MP-10 GN=LPE_01384 PE=4 SV=1 -----SPNGIITNSSATNKQAAIIQITDQLQTHGYVDKQMQASALAREQVASTIID-KFAIPHGDIN---HVLKPTIGILTSKRGIEWDHER---VHIVFFVALNrtVESQMDDIYSyFYSLIQNANRMAALTKAQDVQSIIEILAH-- ->tr|A0A0R1KCN9|A0A0R1KCN9_9LACO Uncharacterized protein OS=Lactobacillus alimentarius DSM 20249 GN=FC67_GL000169 PE=4 SV=1 -----DPRLIIFtEEKDSNYKSALLKLIEQTIKYGYSDDELYDSAIIREKLSSTATD-GMALPHGTTN---HIKKPFIGIIKSKQGIDWLGEs----VHIAFFMGLKgiDATSMKNIYHqLNNIVENKKIISNLINCDDKKKFFTYL---- ->tr|A0A0R1SYW8|A0A0R1SYW8_9LACO Transcription regulator, mannitol operon OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL001655 PE=4 SV=1 -----KRKNILFvDDPTLTPEQAITKIVNNLKQAGYVHEGMLETALKREEQSSTELR-NAAIPHGDPR---LVIIPSISILLNRSGMQWGKNh----IKAVFFIAVNeqLDSELDRLYQhFYLLVRDNQAIERIAQAHSAEEVLKIIDT-- ->tr|A0A0R2CFN9|A0A0R2CFN9_9LACO LicABCH operon regulator OS=Lactobacillus cacaonum DSM 21116 GN=FC80_GL001470 PE=4 SV=1 -----TLDNIIIKNKPVTFEDAVTEISKIAGKKKISNIGLKEAILEREKISSTFYD-EVGLPHATKE---NVKQSAVFVFISEKGIYKEYEK---VNVLFFLLLAddAKHFINEFYEfLNDIVTNKKKIKKIIKATTKAEVIHELES-- ->tr|A0A0R1GWQ5|A0A0R1GWQ5_9LACO LicABCH operon regulator OS=Lactobacillus bifermentans DSM 20003 GN=FC07_GL000227 PE=4 SV=1 -----DPTAIYWRSDLPDAPAAIRFLGQQLIQRGLATEGVLVSTLSREIFSSTVVR-QTAMPAAQVN---EVLQPSLSMLIAPKGINWYGQS---VQVVFFLALDhsAQAVLPEIYQgLTQLKTTA-FVKQLVKCTDAAAAYQLIQQ-- ->tr|A0A1E9TVV4|A0A1E9TVV4_9LACT Uncharacterized protein OS=Aerococcus sp. HMSC062A02 GN=HMPREF2626_03290 PE=4 SV=1 -----DSDLFITsSTELDTQESVIAKLISKAEEKEFISADFKTSVLNREKLSSTAIG-RIAMPHGDYH---YVKQSAVMVYKNESGIKWDKDK---VYIVFMFMVNqeIKEHLSQIYSdFNALISSESTVNNLIKSQSYKEFKTIIRE-- ->tr|F4BSP5|F4BSP5_CARS1 PTS family L-ascorbate (L-asc) porter component IIA OS=Carnobacterium sp. (strain 17-4) GN=ulaC PE=4 SV=1 -----SENHIKVIDYVENWKQAVEIASEPLIKENLISHIYVENMISSVqDNGPYMvLTDYFALMHAKP--GEGVNQQSMSLLVTRNEIDLEG---KPVKIFLILAAEdSQSHLKGLQDVIAIFMDKNKYQTILNGQKK-DIIELF---- ->tr|R2QBR0|R2QBR0_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_02548 PE=4 SV=1 ------ENRITIVDEVADYKEALQRAGQPLLTEGAVTEEYIQAVIDSHDFEDPYtiLGQEVAIPHALPSE--GVNKIGISLLIVRQGFRYSQSHS--LKIVFMIAPIDkKQHNQAIIDILTIAESPEMIEKLTNTTEKHAILTLLK--- ->tr|A0A142KJS4|A0A142KJS4_9ACTN PTS fructose transporter subunit IIA OS=Propionibacterium acidipropionici GN=AXH35_13835 PE=4 SV=1 -----APRFLVLDADTANQEDLYSVVNSHLLSQEAVHETFLEAVSARELKYPTGLdfGhCQVAIPHIDP---EHIITPGVLVCRNAQPTPFHAMDDPErtldVRLTIWPLVTdPQNQTGMLGAVIALLQEETSYQRLLTE-SPEKLEELLAG-- ->tr|F2N8J5|F2N8J5_CORGP Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / -----HTDLIILDAEVASAEEAIRLMGDRLEKLGFVTEGYADMVCDREKTYPTGLpgAsWAIALPHTDP---TLVIRPAVGVIVPREPVEFKMMGAPDttldVRLIMPLVIKdANSQLSLLKTMMGVIADAQLLERIRRSRDPREIIELLRP-- ->tr|A0A0F4LYD5|A0A0F4LYD5_9LACO PTS Gat IIA OS=Lactobacillus mellifer GN=JG30_00430 PE=4 SV=1 -----DPSLIFTDINLTTQTDLFRFMADVLQQKKYIEKPFLKAVIQREAQFPTGMqlQgCGVAIPHTDP---QFIKRSFIFFVRPQQPLLFHKMEDPQqtlnVSFVLLLGLDnSGNHLKILQRLMTMFQKQTLIQQLLSSANNAAICDLLKN-- ->tr|A0A140DVS0|A0A140DVS0_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_16130 PE=4 SV=1 -----DTSLVFLDADFSSRDDLFHTMGSWLKDNGYVNEDYREAVCRREEEFPTGLkvPgHQLAIPHTDS---EYIEKPGLVFVRPKNPLAFQEMCSGDpvdAEMIFLLLVKdKKDQMPLLSGLMARFGDGELMDRLSRETDPEVIADLLDH-- ->tr|R2QKC5|R2QKC5_9ENTE Uncharacterized protein OS=Enterococcus malodoratus ATCC 43197 GN=UAI_04404 PE=4 SV=1 -----EEKNILLNQSFSNQEEYFQKITKKLMTENMVKEGYFESITKREITYPTGLyiGeQSIAIPHTDY---QLSNVTAILVSVLKDSLPFQRMDDPEetvsVNVIIQLLFDsPDKQPQLLKELMNKVTNQDFLQAILGAKSKTEVLTAFNK-- ->tr|A0A1F1W487|A0A1F1W487_9MICO Uncharacterized protein OS=Dermabacter sp. HMSC06F07 GN=HMPREF3157_08995 PE=4 SV=1 -----RPRLYVLDVPKGEgtsFASLTRFVASHLEADGCVTSSWVGAVLAREQLYPTGLplEPPVAIPHADT---THTLKDALVVARLAEPLAFGAMGDSDagalqVRLAVFIVAGnGMAQVEALERLLSILGDGARRERLEAG-SAENARRSFEA-- ->tr|E3G412|E3G412_ENTLS Transcriptional antiterminator, BglG OS=Enterobacter lignolyticus (strain SCF1) GN=Entcl_4261 PE=4 SV=1 -----GETHVRLAAeLPASWQEAISDASSSLLCDAVIEPRYVRIMTDKISEEQPwiMLAEGVIIAHAGID--DGAADTGMALLRLPEKMDFAGYM--QADIVIVLATHNPqKHLKALAQLNEFLEFHDGGNCIRQARNKTELLNAIAI-- ->tr|A0A239V8A7|A0A239V8A7_LISWE Mannitol-specific cryptic phosphotransferase enzyme IIA component OS=Listeria welshimeri GN=cmtB_1 PE=4 SV=1 -----SSNMTRVVKSVPNWHTAIELTAAPLLEAGFIDQTYVNAMKSLYPEIAPyiVLKGNILLPHARPE--DGVNKFGLSILKVEDGLIFNGK---KIHLLVVLAPVDKkKHLTAMFQLLTIASNQQVIDKLKNATSGTAICQIFKE-- ->tr|X1ES49|X1ES49_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S03H2_15833 PE=4 SV=1 ------PELMNFDVVPGDKMKILGQLTFPMIQSKFLTrrKYFLDRLIERENMMTTGLGNGVAVPHPRQPIPNLFPESAIAIGICKEGTDFDADDGKTVYAFLTVCSSDDvHHLRILARIAKFASDKSATKKLIKARIPEEIIDILK--- ->tr|G0GDZ4|G0GDZ4_SPITZ Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) GN=S ------PECVLTGFSATREEEAFQKMVDAAFRAGRVKdpEELVRLVLIRERQCSTVMRPGVAFPHPRAVGPEVVPEYALVLAISPEGVPFSDAPGDgDVHFIALFAIPSLqLHLKILAALGELFSHEEVQERLLSARSPQEVISHIT--- ->tr|A0A1G1J4J5|A0A1G1J4J5_9BACT Uncharacterized protein OS=Omnitrophica bacterium RBG_13_46_9 GN=A2Z72_00480 PE=4 SV=1 ------ESCINMDMKSRKPDGILYELAEIAQESGIAVsiENLLIQLKKREQMLSTAIGKGVAIPPPRNPSDELFRKTGLIIGRSAKGLDFDAPDGKKVHLFFMTCATDVvLHLNLLSKIARLLDADGFIKRMIRVKSKKDIMKLLL--- ->tr|A0A1W9VNX7|A0A1W9VNX7_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_7 GN=B6229_07005 PE=4 SV=1 ------EKSIITDLKGQTTKEVIHELAEKAYINEFVAdkNIFIKQLLEREQLTSTSIGQGIALPHLRKPNGNIVTEPKIVIGVSKEGIDFDSLDGEKTTLFLLLLSDSEvVHLKLLSKITRIFGIDNAISQIKQLRKPEEFVKFFN--- ->tr|A0A0H4KJR1|A0A0H4KJR1_9BACI Uncharacterized protein OS=Bacillus endophyticus GN=BEH_10860 PE=4 SV=1 ------RNLIFTNLDMTSKDEVIEFVSASLQKRGYVRDQFYESVKNREQKASTDLGNKVAIPHGEN---QFVQKSCIAVVTLKEPIKWGRSEVSIV-FFIVLKVENKQSmRPILRELYQVLDSKRILQMMERASCEDDILHILGGK- ->tr|A0A0D0GAA6|A0A0D0GAA6_9BACI Uncharacterized protein OS=Bacillus thermoamylovorans GN=B4166_1376 PE=4 SV=1 ------PNSIFVNNHFNSMKEILEYLISYLEHEDLVTPLYRKSVFDREATSSTALETGVAIPHGNP---DYVKKTSISILVNSKKVHWGNEKVDII-ILLSVAKNDVNHiSSIISQIYDVISDRNRMETVFFGKTKENIYEYFYDH- ->tr|E7G876|E7G876_9FIRM Uncharacterized protein OS=Coprobacillus sp. 29_1 GN=HMPREF9488_00964 PE=4 SV=1 ------EKMIFWDMEFKNKDECLKFVMEKLYSAGYVKEGFEKSILEREKIGTTALDSGVAIPHASI---EYTRETKIVIVNLKHKILWNDKKIDVV-ALININQKDKANvRNLLGELYQFIRERKDVEKYFKMNTKDEFIKSINQ-- ->tr|A0A1L8WKN4|A0A1L8WKN4_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL002828 PE=4 SV=1 ------EEVIFLNETITSKEQCIRKITKALLQADLVTESFEQAIWDREKLGATDLPTGVAIPHPAP---STVKESKLVIMTVAKPIRWNLRMINTV-LMICVAEKDLKDiKGILSEIYRIVESKRNVDKTILGKTKQELMSILGGE- ->tr|A0A1L8TBZ5|A0A1L8TBZ5_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL000719 PE=4 SV=1 ------VAYIYTKKHFSDKQTCLNWLIDKLEKGEIVTRGFRKEVFDRETIGETALATGVAIPHASP---QNVLQTKIVIVTLTKPITWDKRKVHSI-LLMCIAKSDRTLvRGVMTDIHKIVQSEKQLKSIFGDREAVEIYNDIIGR- ->tr|A0A1Q2C4U3|A0A1Q2C4U3_ANAHA PRD domain protein OS=Anaerostipes hadrus GN=DO83_03100 PE=4 SV=1 ------GKFIFLKQDLDSKEKCLDFIIDVLEKDNAVYDEFREAIYKREKLGVTCLDTGVALPHADP---QTIKKSRIILLTLKHPVDWGGTLVSLI-VVTAFPEEEMNQiRDVINELYQLIGEKEDVNAFIRFETIQEVLKVFHES- ->tr|A0A0Q3QQY1|A0A0Q3QQY1_9BACI Uncharacterized protein OS=Bacillus solani GN=AN957_17115 PE=4 SV=1 ------SRYMFINEEVETKEDCLNKMIQRLEEDQIVKSSFKKSVYEREKLGNTIVQGWAAIPHAMS---TMANETKISIMKTKQPIKwNHETYVSFI-ILLAVAEEDLNQvRSLLAHLYKIIINSDRLGsghSFKSMTTPDDLIAFLLCK- ->tr|A0A1L8QQQ2|A0A1L8QQQ2_9ENTE Uncharacterized protein OS=Enterococcus aquimarinus GN=RU93_GL000482 PE=4 SV=1 ------KEFVYIDTDFSTKEELLNSVGKELVSNNYVTENFVTSLISREELGGTDLPAGVAVPHGNP---SDVKRTTIAIVKNKKKFKWDTYYVDVI-FVIGISYENRADtRKILSDIYNIIDTSKKLEDIKQAQCKEDLFIKLGSE- ->tr|A0A1T4P0Z1|A0A1T4P0Z1_9BACT Transcriptional antiterminator OS=Anaerorhabdus furcosa GN=SAMN02745191_1833 PE=4 SV=1 ------PDFIFHNKKFKTKNECLDYLIKIYQKRKYVNEEFAESIYEREKMGDTSMYTGAAIPHASP---ETVLKSQISVVTLKDKIKWGSQDVNLI-VFIAVAKDDMDRiKNVLSKLLDILESTQTIEKMVHASNKEILVEILEES- ->tr|A0A1T5L0L9|A0A1T5L0L9_9CLOT Transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_02268 PE=4 SV=1 ------LKHIYMENDFKTKEECLDYLFQNLYEDDCVDKKFRDDIYERESLGSTYLSLGVSFPHAMP---TYVRKSAISVLLLPNGVFwDEHRVY-LV-IMLAIKSDEIKEtIKDLPVLYKKVLDYQFINNLVRLNEPEDIKKMLLE-- ->tr|A0A242NUC9|A0A242NUC9_9GAMM Uncharacterized protein OS=Gilliamella sp. A-4-12 GN=B6D06_07445 PE=4 SV=1 ------ADLIELNVDIQHKSDCLNLLISKLEDKGLVTKNYRDSVLYREEIGDTSIENGIALPHGSP---MFVIKSSISIMTLKRPIKWGMIDVSII-IMVSLSEDNINSiNDVFTEIYEIVSNKQAISSLKNLINFKQLKQFLDNQ- ->tr|A0A219BEI1|A0A219BEI1_ENTHR Transcriptional regulator ManR OS=Enterococcus hirae 81-15-F4 GN=F522_01960 PE=4 SV=1 ------DGWMFLNQDFDSRESVLSFITEKYKEEQLVKDNFLEVVLQREKLGATGLSSGVAIPHANP---KYVVKTKISIITLKNKITWGDVDVRVV-LFLAIAEEDMIQvKNMIALLYDVFVSPERIKSIASKETRNEIINEIIGK- ->tr|A0A213I727|A0A213I727_STREE PRD domain/PTS system IIA domain-containing protein OS=Streptococcus pneumoniae GN=licR_4 PE=4 SV=1 ------LETIFLRKEFKNKEGLIEYVGNSLNKNKFVDYSYLESIFAREAIGITALEYGVALPHASS---KTVNRTHIAICTLSHPIDWDGIPTSLV-IFMNFEDDEVENiRYIVDKIYKKINSKEKVDKLVGCKKPEELIEEIRSI- ->tr|C2K0U1|C2K0U1_LACRH PRD domain protein OS=Lactobacillus rhamnosus LMS2-1 GN=HMPREF0539_2776 PE=4 SV=1 ------EEDIQLGVKVDTPEEAIRIAAKPLKAKGAINQHYVEKMISPDDgHSLDAyiISPGVALPHTDPKN--GAQRVAIGITTLEKPVFFSQAKSEKVKFIFVLSAVNPtDHLMVLQDLMDLLGDANFMKLLADkKTDSRKVMQYLR--- ->tr|A0A140DYU9|A0A140DYU9_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_26920 PE=4 SV=1 ------PGLIRTHVQCETRPEAVRIAYAPLQERGMITEEYIRRTIAGMDLAGPYvvIAPHTALLHTAAEH--GARQQGLSLTVFETPVVFGSPENDPVKYAYALSVPQgTpSHLTAMAGLLKLLEDPGFADICDTHD-PRRIWDSIC--- ->tr|L2Q8C9|L2Q8C9_ENTFC Uncharacterized protein OS=Enterococcus faecium EnGen0038 GN=OKI_04765 PE=4 SV=1 ------KAFIQFHLPATTYAQAVQQSAAPLLAERVLTENYLAEIIHSAAERKSWmmITDGVALPHTKPMY--GANAIGLSLGVLETPILLENG--REMRYIMVLSAIDNhQHLKAIAQLVHFLEDGAFFELLQTTDSQEKVFAYIV--- ->tr|A0A0W7V275|A0A0W7V275_9STRE Transcription antiterminator BglG OS=Streptococcus gallolyticus GN=AU078_05260 PE=4 SV=1 ------IKFIQTNVEISDYEEGICKAAKPLLQSGIIQNQYLEKLIDD-YHKGVImrLTSLFCMPHATDT---GGNNLGMSLVVLKHPFIFKDK--SSVKYILLLSAPKSsVHLLAMNQLLKLLGQENFYEALDNF-SPKDIYHYIL--- ->tr|A0A173WPL2|A0A173WPL2_RUMGN Probable licABCH operon regulator OS=Ruminococcus gnavus GN=licR PE=4 SV=1 ----LDETIILLQKKYKSMEECVKEVCAILEKDGCIEDGFYDSVISRERIAPTNIVDGIALPHGLNK---YVKENRIAIVTLKKPISWGNDRVSTIF-LVAINFSNIMVSkKALEELYFCISDEDFISELKSCMDVKEVYQLFETV- ->tr|H1BPJ2|H1BPJ2_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_02241 PE=4 SV=1 ----LDKETLLLKQDYEDKDTVLEKIHTIFMRNGYVSEGFLASMKERERMAPTEMGNGLAIPHGISK---YVKKEKILVMTLKKPIVWDKEKVDIII-CLAFNFADKERSrKLISNIYQFIKSKDTIHRVRECTTEKAFYEIVRSL- ->tr|T4N853|T4N853_CLODI PRD domain protein OS=Peptoclostridium difficile P28 GN=QSI_4338 PE=4 SV=1 ----LHEKNIYINDGKITKDEIIHQVCMGLNKEGCVDAHFETSVWEREQKGGTDIAVGGAIPHGAVS---TVRKTQLALWINKEPVKWSKYRVKVIV-FFALNSEDTAKTkVILEEAFSLIKTKEMIEKLSSMKNKKAVIKYIFGG- ->tr|A0A1G8BAF3|A0A1G8BAF3_9MICO PTS system IIA component, Gat family OS=Agrococcus jejuensis GN=SAMN04489720_0806 PE=4 SV=1 -------DACMVGVVAADAVGVLRQIADLAIRAGHAAPSFGEALVTRERAHPTGLPTlvPVAIPHADPS---HVLEAGFAVATLARPVSFGVMGTaddHvDLDVVIVLLVTEaHAQVEVLASLVDMVQRDGWDASLRAARTPAELAASFD--- ->tr|A0A1L8XB69|A0A1L8XB69_9ENTE Uncharacterized protein OS=Enterococcus saccharolyticus GN=RV16_GL001442 PE=4 SV=1 ------SKSILIEENQVTWHEALDALSQPLISEKIITPQYLTALKQEMAEIPpyMIFRNRLALPHTEPE--KGALGVAMSFGIFKEGFLTETDE--RIHIVVLLASNdKEKHIDALLELMDLSGRDDYISKLVECQTAAQAYKILH--- ->tr|A0A1L4C0S3|A0A1L4C0S3_9LACT Uncharacterized protein OS=Marinilactibacillus sp. 15R GN=BKP56_10695 PE=4 SV=1 ------TSMIRIVDKVSDWQEAMKVAAQPLLETGKISSQYLKALNNQYPVVSehIVLQRNIAIPHAESE--KGVKELGMSMLFIKEGIPNFDGS--DLHFIVVIAATdRKSHFTALMELMKLAGNDALLKELSKSGNEDEIYQVIL--- ->tr|A0A1L8WAK5|A0A1L8WAK5_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL002085 PE=4 SV=1 ------PESIILLDEEESWGSVLQKTTQNLIERDIVEPRYLTSLQEQFPVVKpnILLGNSIVIPHTVPE--NGTKNLGMCFAKVKQGFQS-GEQ--RFYYVVAISAVdKKQHIQPMMELLKIASDSKMLDKLAAADSKEEILALIA--- ->tr|A0A1V9S9N8|A0A1V9S9N8_9LACO Uncharacterized protein OS=Lactobacillus salivarius GN=B6U49_08195 PE=4 SV=1 ------PNFINVIEKIDNWDSMIELGCKPLLENNAINNNFISNLKNNINNILdyATLAKRIALPHLGKI--DGAKKIAMSLVLCRNGIKDKKGN--KYYIVVFLSAPeKIGHLKAMKQLMMIAKNDELYSKLIKCKNGDEVYKKIY--- ->tr|A0A1T4LYQ0|A0A1T4LYQ0_9ENTE Transcriptional antiterminator OS=Pilibacter termitis GN=SAMN02745116_00869 PE=4 SV=1 ------DMSIQIFQN-ESWQEVVQSLGNILIEKKIIAQRYIDEVLRQYTEITpqIALRETIALPHVASE--FEVYGTGLAMGIVKEGICFKKTQ--SIYLVILFATNtKEAIAETMLELVQLSGQTEVIEKLKKSTNAKEARGYLE--- ->tr|A0A0S4V7T5|A0A0S4V7T5_RALSL PTS system, glucose-specific IIA component OS=Ralstonia solanacearum GN=RUN1985_v1_620050 PE=3 SV=1 --------------------VLAPLSGRVVPIEDVPDPAFAQK----------MVGDGLSIDPATD-----------VVLAPIDGrvIDFHDAR-----HAIVIADASGVEIMVHVGLDTVMLAGQGFEALVGKGDTVRAGQPL---- ->tr|A0A1Z4SF75|A0A1Z4SF75_9NOSO Phosphoenolpyruvate-protein phosphotransferase OS=Nostoc sp. NIES-4103 GN=NIES4103_59140 PE=3 SV=1 ------------------------------------------------------------------MV-------GIVIV-------SHSKQ-----LalgVQELAAqmvQGNVPLAVAAGIDDA-------ENPLGTDPmqvYEAIASVF---- ->tr|A0A1A5WVY9|A0A1A5WVY9_9BACI Uncharacterized protein OS=Bacillus sp. WF146 GN=A6764_19795 PE=4 SV=1 ---------IIVTEEVVGREQILTQLGGRLVQSGAVADEYVPTILEREQQFPTGIeleSIHIAIPHA---DAAYVRKPAVAMAVVKKGVSFRSMAdpeKDLpVKIVIMLALeKSETQLRVLEQIMSFIQHADRLQELVEMESGEAVFRALK--- ->tr|A0A1L8TAT7|A0A1L8TAT7_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL000987 PE=4 SV=1 ---------HGLISEETDRDQLIHLLAAEMAKYGMVEPCYGASVLEREKEFPTGVptmPVPIAIPHS---ERSQVYKPGIGVAVLRNSVKFSSMEdptCLLdVRVVFMLAAsLNDEHLHMIKDVMEIIQDSEVVNALLAAETTKEIEAIMH--- ->tr|A0A212J6Q2|A0A212J6Q2_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=uncultured Clostridiales bacterium GN=KL86CLO1_10598 P ----LNEDGILLSASVANKEEAINMLISGPHRFGVLAdAAtCHADVLVRESQGTTALPGGIAIPHAKSRG---VASLGVNVLTVPGGVDFGAADGSKSRLVFLLVGPEHdpsGYLEMLSSLLKLFTKNDQlVERLVAAKTSGEFLSIL---- ->tr|A8RD41|A8RD41_9FIRM PRD domain protein OS=[Eubacterium] dolichum DSM 3991 GN=EUBDOL_01582 PE=4 SV=1 ---------------YATGEEAILDICSKLQQKHCVNESYAQEVMEREALSSTAF-GGFALPHS---LHMNCLRTTIYVHIQEKGIIWGKQT---IHVIFLLSVSKQERkmfREIFEYITDIINDAEKFSKIRKAKTYEEFIHLFLA-- ->tr|H1BB73|H1BB73_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_02456 PE=4 SV=1 ---------------LKVKEDILHFMCEHLEAEGYTDSSYYDRVMEREAMSCTVF-GKTAVPHA---LKACAKHSGICVYTSDHGILWEGRQ---VYIILLIAIHPEDQlrfNEFFNKITERLCEDDKTARLISCVSYEEFLEALVY-- ->tr|A0A099I3S5|A0A099I3S5_CLOIN Uncharacterized protein OS=Clostridium innocuum GN=CIAN88_17880 PE=4 SV=1 ---------------FSSASACIRAMCAKLQRHGFADERLFDEIMEREHMSSTAF-DHFAIPHS---TYMRSKKTIINILISKKPILWNSNQ---VSIVILMCFNKHDRalfQSVYETISAVLIERENVKKLTACNSYDEFIETFVS-- ->tr|A0A1T4XQU7|A0A1T4XQU7_9FIRM Lichenan operon transcriptional antiterminator OS=Gemmiger formicilis GN=SAMN02745178_02180 PE=4 SV=1 ---------------CTTREEVVHHMCSRLLALGCTTPAFEAAVMERESISSTAF-GQFAIPHT---LKMCSPRTCMAVYVSRTPICWDDTA---VNLVIMLSFNPNDRkifYDIFEPLSMILLDSNNLKGALLCRDYTAFIDFLVE-- ->tr|A0A1S8YKQ1|A0A1S8YKQ1_9ENTR Uncharacterized protein OS=Izhakiella sp. D4N98 GN=BTJ39_13245 PE=4 SV=1 ---------------FSNENQAIEFMAQALNQQGYVDENFIQDVFQREHSYPTTF-GSIAVPHS---MKMDAIKTGLCVAISEKPFPWGDNM---VNMALMFSINKAERaifYDIFDNIIVLLLEPANLKKALECRSWKEFIVTITT-- ->tr|D1APG6|D1APG6_SEBTE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3159 ----LDKKYIFLHRDFGNKEDVFHFINGILLEDGYVTEEYLPKVLERENTFPTGMElekINVAIPHIDSK---YILKENLFVITSKKGIEFNNAENNgeklNVKIIFGLLIREhNTHINFLVKLIELFQENDKLEQILESSDKDEVIKILKD-- ->tr|A0A1M6DMT1|A0A1M6DMT1_9FIRM PTS system, galactitol-specific IIA component OS=Propionispora hippei DSM 15287 GN=SAMN02745170_00935 PE=4 SV=1 ----VYPELIWVNKSFADKEDLFKTVAQSLYNKNFVTETYYESLLAREIKFPTGLDmedYYVAIPHSECG---NIKKEFISVVVLEKPVTMNKMDDPqielPVEYVFFLGMNNdQDHLKVLKEVITIIQNKHLILEMKKTSSPDQIAGLLTK-- ->tr|L1Q7J5|L1Q7J5_ANAHA PRD domain protein OS=Anaerostipes hadrus DSM 3319 GN=HMPREF0369_00714 PE=4 SV=1 ----LEDPYIRIIKDKFKWQDAIKVSGEVLLENKLIRQSYIDSIIYKTDQYGPymFITKQVFLAHSEIE--DGAQSMGLSMTIFKKPVEFITldGKQRFAKIILMLSAQDQkSHIRLLNDIMTIFSEQKNEEKLWGQKEILDVKNVLYEL- ->tr|D3AR09|D3AR09_9CLOT PTS system, Lactose/Cellobiose specific IIB subunit OS=Hungatella hathewayi DSM 13479 GN=CLOSTHATH_06065 PE=4 SV=1 ----LTEDRILFLDRngrerteekrewsgdgySTGWERALYTAASPLLERGSMSEEYVRCIVDRMVEAGPymFITRDLILAHARPE--NGVKHLDLSIGIAADGIEFEGG--KTARVIFCLVVEDQqKHMGILQDIRKTLAKPRQIDELVRAESAYEVCDILRSR- ->tr|A0A0V8QCQ4|A0A0V8QCQ4_9FIRM Transcriptional antiterminator OS=Acetivibrio ethanolgignens GN=ASU35_13220 PE=4 SV=1 ----LKKNRVQILEGHFQWQEAVRCAGKSLVEAGSIEKRYLEKIISQILYYGPfmFLNQGLVLAHAKPE--DGVNYMDVALTVFKEPVAFSEY--HYAKIIITLAVEDQeRHLGILKDIMAVFGEERHTEELALLASSEEILKYMQQY- ->tr|A0A1L8REV6|A0A1L8REV6_ENTAV Uncharacterized protein OS=Enterococcus avium GN=RU95_GL002650 PE=4 SV=1 ----IGQHNIQIAATPLGWREAVAMAAEPLRATKTIDQEYVEEMIRLVDVYGPyiVLGKNVALAHAKPE--NGVNRLGISMLVCPEGIYFDEE--NEINVLFVVASPNEyEHLNYLNDILKFAKNSDAVKSIIQTKNVTECYELAKGM- ->tr|A0A0Q1AP08|A0A0Q1AP08_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. SDB GN=APR54_07580 PE=4 SV=1 -----KLECCDIDFKAQDKNDALLKLAALLKHNdslkDTSQEKIFRSLKEREEMGSTGFGKGIAIPHCRLEGLNeFVIGLAV----CSKGVNFDSLDRKKTKLFVTIvgpLEDRSGHLQLLAKVSLILKDNIVVENLLKAKTKIGLYEEFF--- ->tr|K2QAI0|K2QAI0_9LACT PTS system, fructose-specific enzyme II, BC component OS=Lactococcus garvieae DCC43 GN=C426_2087 PE=4 SV=1 -----NPNNVFFAEENFENNEsLFHFIAKKAKDLDYVQseEECFQGLVERESQSTTAFQDSFAIPHCK---SDTVKQPQLLFIKS-SAIKWESLDGSDIEHSFALLIpstGAKEHLKYLAQIARSLIDDNFRHEIKASASPKEAYNIIK--- ->tr|A0A0R2LBS1|A0A0R2LBS1_9LACO Galactitol pts, eiia OS=Lactobacillus pobuzihii GN=IV66_GL001689 PE=4 SV=1 ------KKLIFYDVDAVDRKDLYKKISDELVKKGFVKESFYQALNAREDEFPTGIVtkhLPIALPHANPEN---VNKPFIAVVHTKKQIQIqqmGTNEEEKTKNFffLGIVE-EtqDLQVKLLQRFMEIMNDQNFVEQFVTIKNPETIYDFLIN-- ->tr|F0EJG2|F0EJG2_ENTCA Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Enterococcus casseliflavus ATCC 12755 GN=HMPREF9087_11 ------EELIILNLDSADRTELFKQMAKIFNDKGYVKEKFYDFIVEREENYPTGLDlgtHKVAIPHGDPEY---INHSFISVVTLKRPIKIkkmEDADEEIdVDLFfiLGLSD-GTQHLQILKQVIGLIQQEAFVKAIQSATSAKEVMEKISA-- ->tr|A0A1H4LX82|A0A1H4LX82_9ACTN PTS system IIA component, Gat family OS=Atopobium minutum GN=SAMN04489746_1004 PE=4 SV=1 ------PELVFFDFEATDYVDFFQKFSQIMMEKGYVKDSWCAAITERERTYATGLLfenLPVAIPHVDPQH---IIKPYIAIIKPKTSISFepmAGmVDHPIdTKLIvnLGLLKHAEGQVEVLQAMMGMFMDDNAVADILSQTTAEGMVDCFKR-- ->tr|A0A242JX10|A0A242JX10_9ENTE Uncharacterized protein OS=Enterococcus sp. 9E7_DIV0242 GN=A5888_004053 PE=4 SV=1 ------EDLIFIGQELRDRAELFKWFNGCMIEQGFVNESYYESILKREQQFPTGIQtptVGVAIPHADPDN---LNKPFIAVVRPKRGIEFepmGIAEGNIqAELIfmLGVLK-NGDQVIALQKLMNLLTNNEAVQQLLEVRTCKEMMEIIRV-- ->tr|J3TRJ7|J3TRJ7_MYCGL PTS system fructose-specific enzyme EIIABC component OS=Mycoplasma gallisepticum WI01_2001.043-13-2P GN=fruA PE=4 SV=1 ------PEFVFINLKQKNRDDILKELATRAVKLNLATnqDELYQAFLAREKESSTALPDLFGIPHARTAT---VKQPALLFAKLHQAVEWDEEK-KQVQYLFVILVPqdaSNTHLEIISNVAKLIMDKNANQKLISSNNPDEISKLIVS-- ->tr|A0A0C5X205|A0A0C5X205_9MOLU PTS fructose transporter subunit IIABC OS=Mycoplasma dispar GN=MDIS_02795 PE=4 SV=1 ------KDFVFLLQNLKTKDEVFEFIAKQSLKLNIATdeKQIIKDLQNRESQIPTGLESGFAIPHTQSES---VLKPALFFISLKDGIDWQTFDNSLAKYLFCILLPkngfDEAQVNVLAKIASLILDPKVKEI-LKSTEVDFVFANLAK-- ->tr|A0A1S9CRS5|A0A1S9CRS5_9FIRM Uncharacterized protein OS=Epulopiscium sp. Nele67-Bin004 GN=ATN35_01655 PE=4 SV=1 ------EDLVFINADFSDKKDFVEKAAEALAKKKLCTdkDAFVKDVFAREEQGDTDLpEEGVAIPHAKSSA---IKKPKIVAATLSKPWAHPDS-DNGISMVFLLAMPknaADDHISVLSSLSTLLLDENEVKALRAAKSPKEFIKLMHV-- ->tr|A0A1F4U8B4|A0A1F4U8B4_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium RBG_13_43_14 GN=A2Y85_05180 PE=4 SV=1 ------KDRVNLMIKPGKKNKVIEDLVFLIKKG-SDAELIVSTLMKREELGSTGIGKSIAIPHCRSLAVD---KLEIAVGRTTKEINYNAIDKKPVSLIFLIIAPpqdpGNQYLLTLGKIVQIAKELTKKDLVFKPQTPEEFIILIGQ-- ->tr|A0A1G0XBA6|A0A1G0XBA6_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_00055 PE=4 SV=1 ------KES-VLILEGLNKRDVINEILNAAEKVsPIARDIMDKAIWQREKMMTTGLGHHLGMPHIRHSKLG---EPILLVGVCKNEItDYASVDNLPIRVIVFLAAPegdQENYLKLLGSISSKFRDEtLIAEILENIDKPSKILTLLKK-- ->tr|A0A235BZM1|A0A235BZM1_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium JGI_Cruoil_03_44_89 GN=CH333_00330 PE=4 SV=1 ------KGRFKNHLRSREKRQAVKELFETTDQP----PPVLQRIYAREREFPTGIGCGVAIPRYLGKEVK---EATLSLGLSRGGIEFGTLDRKPVKIIWLLIFPeheRKKYTEILVRLIRLANTEEFRSQVLNVASVEELVELIKD-- ->tr|A0A1L8WCP9|A0A1L8WCP9_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL001307 PE=4 SV=1 ------EQLVWIQQDFTSREALFSFMSQQLYEKGYVNEGYQEEIISREEKFPTGLvleNYNVGIPHCDSQYVKkdfiaiVILSNYIQMNQMDK----PDNEIPVKYLFFLGLQDANNHLKILKKIMKVIKSEQLIHRAENSQSVKEISELLK--- ->tr|A0A0K9GSZ3|A0A0K9GSZ3_9BACI Uncharacterized protein OS=Bacillus loiseleuriae GN=AC625_09460 PE=4 SV=1 ------DNLVFLDKEYKDFEDVLSHVMKTLINENYAEKDFEEALLIREKEFPTGLqldGYAVAIPHGGSQYVKqdfismVTLKNPIFMNRMDN----PEESLAIDILFIIGFGKSDTHLQCLKQLMGLIQDPKVIEDLRKGTSIMSVL------- ->tr|A0A242CWK7|A0A242CWK7_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_003762 PE=4 SV=1 ------LENIKLNQQYKNREDYLKKMGEQLLSAGLVNEGYSTSIINREEIYPTGLatgEINIAIPHTDYQFSRttdifiTVLKTPIAFFRMDE----PEKTVEVSIIVQILFDNPEKQPDILKELMEIITNQRVLKEMIAAQEPKEVLQHFQ--- ->tr|A0A0A8E7M8|A0A0A8E7M8_MYCFL PTS system fructose-specific IIABC component OS=Mycoplasma flocculare ATCC 27399 GN=fruA PE=4 SV=1 ------HDTIFLDKNFDSKDKALQFLSQELKNKMYISDAiqAKKLFQKREIQSSTGIGQAIAMPHIG---DDVVLKNTIMFVR-TTNLDWNAIDNLPIKYIFAIVLskneRDNSHLEIIQKLSQLLINPKFVTNLETIKTAQEFLNLID--- ->tr|Q98R81|Q98R81_MYCPU PTS SYSTEM, FRUCTOSE-SPECIFIC IIABC COMPONENT (EIIABC-FRU) (FRUCTOSE-PERMEASE IIABC COMPONENT)(PHOSPHOTRANSFERASE ENZYME II, AB ------KNFIYFNKEFKDKNQALKFFSNQLLTQGYAHEEkkVFDLFVQRENELSTGIGDSIALPHIR---SDVMKKSTLMFAK-VKDLNWDSLDGKNVKYIFVIAMskdeGQNSHLEVIAQLSKLLLNKDFINNLNSINEAEKFISLVD--- ->tr|S1M0A2|S1M0A2_9ESCH Uncharacterized protein OS=Escherichia sp. KTE159 GN=A31E_02769 PE=4 SV=1 -------DLVFLRQRFIDSDDFFHTVNEKLLAANLVTIDFLQNIRLREREYPTGLAlesFSIAIPHTDIKFIK---EPFVAFYQLAEEMPWNEMgaDENklKIKFIILLGlVDTSSHIDFLQNLITLFSTENHADWLSKTQSSHDATNYLNK-- ->tr|H3NDR6|H3NDR6_9LACT Uncharacterized protein OS=Dolosigranulum pigrum ATCC 51524 GN=HMPREF9703_00697 PE=4 SV=1 -------NLVNIENKSTSLIDFFESASRELVEENFVEESFFEAILSREQIYPTGLVlenINIAIPHTDVDHIK---KPFIYINKMEDDIEFTQMgsDDKkvIPEYVIILGiKEPKKQVTLLSTLIELFNNSNFLDELQNCNNNDDLIKLFKN-- ->tr|V9HN81|V9HN81_9FUSO Uncharacterized protein OS=Fusobacterium ulcerans ATCC 49185 GN=FUAG_00208 PE=4 SV=1 ----INMKNIKVMEEISSFEEGIKIAGEMLIESGYITEDYIKSCIKAFNdqGAYMIIGGNTVLPHSD--NFKSVIKTGYSFLKLKKPIIVEQDDENllNIENIILLASSDgKNHRNSLLDLKNMIDKYKLEKSIHNCKTEKELLKKLT--- ->tr|D1ARA3|D1ARA3_SEBTE PTS modulated transcriptional regulator, MtlR family OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_3555 PE ----LTLGNIMVSDKKTDWIETVNTAGGILLKNGYINEGYIKNIIGNINknGVYMVLKNEFILLHAE--KQNNVFKTGIAFLRKKFPVEFPGK---yMVRNILAISCHSkEELSGSFEDILKLSENTGFLEELEDVRDSEAVFCLIK--- ->tr|C3WAJ1|C3WAJ1_FUSMR PRD domain protein OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_00440 PE=4 SV=1 ----LPAENIVITDEGFNWKNAIWKLGDLFIEKKLVSSSYIKDIIKIVEdnGAYMVVDERFGIFHAK--NNDNIFQTSLMLLVSKKQIQIKDK---KTHLILILASKDgHEHLQSLIEFSKIFESKENIDKILKLSSNKRIFDFIS--- ->tr|C3WF15|C3WF15_FUSMR PRD domain protein OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_02033 PE=4 SV=1 ----LPLKNIKLNLELKSWKEVIEKSGELLLKNQYINKKYIEEMKNKIIelGTYMVIDNKVLLPHGE--MKTNVLKTGISYIQLKNEVEFPGG---lPIKHIFALCTLNsEEHIKGLLELKELLEEKDLRIKLEKCFNEMEVISLLK--- ->tr|D1AVN6|D1AVN6_STRM9 PTS modulated transcriptional regulator, MtlR family OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 1065 ----LSSENIKLNASARNIDEALKIAVNLMVENQIVEKEYYNNIKQQIDkyGKYIQIGNMSILPHGK--IDDRVKKTGFVLVTLKDEIDFFGA---KIRIIIMLASKNkEEHLDAILDINKCLKKYNFEEELLKISNKEEISKFLK--- ->tr|C3W9R0|C3W9R0_FUSMR PTS system, Lactose/Cellobiose specific IIB subunit OS=Fusobacterium mortiferum ATCC 9817 GN=FMAG_00159 PE=4 SV=1 ----IEPFLINEIDKVDSIEEAIKICASPLFEYKYVDNSYITSLIKTSTtpkNTNIYIGEHTIFPHCS--NKNNVFDTKFSFLKLKEPIIFKNK---KCKLIICFCTNQkNIYHNFLFKLFELIEKEEEEFYK---LPLSEYYDYLN--- ->tr|A0A1T4K790|A0A1T4K790_9FUSO Transcriptional antiterminator OS=Cetobacterium ceti GN=SAMN02745174_00355 PE=4 SV=1 ----LDKNSIVRMEKISSWEEGIKIAGNILMEKGAIKETYIDGMIETIKkyGSYMVLAPGIVFPHAR--TEENVIKSSFGILQLDEGVLFPGN---kLIKTIVAFSSRDnKEHIEAFVEIVEIFNGQNFSMDNF--INKIQ--------- ->tr|F0Z0M1|F0Z0M1_9CLOT PTS system, galactitol-specific IIA component OS=Clostridium sp. D5 GN=HMPREF0240_02652 PE=4 SV=1 --------KLIFNGLEGGFENMIYTAGEKLQELGIVKSSYPEAVIIREKEYPTGLegvHGNFAIPHTYSE---HCIGSALSIIRPPKPLEFVRMDdHSKsilCGLIVLLAIDKPeKQLSMLRKLMRAMQDVEIFHILESERSSKAVVETLR--- ->tr|R8XPL6|R8XPL6_ECOLX Galactitol-specific phosphotransferase enzyme IIA component OS=Escherichia coli KTE33 GN=WEW_01241 PE=4 SV=1 --------FVRSDIFFANRREALTHIGNEMVAQGVVHDSWPQALIAREAEFPTGImleQHAIAIPHCEAI---HAKTSAIYLLRLADKINFQQADDDNevaVSLIIALIVENPqQQLKLLRCLFGKLQQPDVVETLINIPEVQ-LMEYFK--- ->tr|W7BEG0|W7BEG0_9LIST Phosphotransferase system fructose-specific component IIB OS=Listeria aquatica FSL S10-1188 GN=MAQA_02262 PE=4 SV=1 -----RNDLIFTDVQVSSQEECFEQLADIAVRSGLATNkkAVVSGFEAREKESTTGMEHGIAIPHTEL---AEIAKPALIIMKLADGVEWNSLDDSETRLVLAMLIPkggAHGHLAILSEISKLLVHESFINELMQAKTKNEIEQLFKEK- ->tr|V6IX49|V6IX49_9BACL PTS fructose transporter subunit IIABC OS=Sporolactobacillus laevolacticus DSM 442 GN=P343_13245 PE=4 SV=1 -----KKENIYFEKDINTKDKLFQFIAENTYKNGVIEDraKLIEAFQKREEQGSTGMEGGFAIPHAQS---DTILEATMLVVKLADPIsDWQTFDQKPVSFVIAFLIPpkgSEAHLHYLSDTAAKLVNKNTVNQLIDAENADLIYDLLG--- ->tr|E3H875|E3H875_ILYPC Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_1526 PE=4 S -------------LEAGNKEEAINNLADIIGEKGVVKDvhEVAHAIMAREKLASTSLGKGVAIPHCRTD---EVNETICVCGLIKNPVEWDSPDGkpvDIVFLVITPKEKPQEYLKVVRAIITTIKKLDLDGRVNHDLLRNILLT------ ->tr|A0A1V5XX12|A0A1V5XX12_9BACT PTS system fructose-specific EIIABC component OS=candidate division BRC1 bacterium ADurb.Bin183 GN=fruA_3 PE=4 SV=1 -------------FKIKSKGEAIWELIRSLHYAGHIHNpgEVLEIILKREHQGGTTLGDGISILHGRLP---YIKKPVVTMGLIPSDhkVNFGTAEDapvDIVYMVLSPQDKPEIHLQVLATLAMILSNQEARESLRHAKDEFEAFNVI---- ->tr|A0A1I0FWV2|A0A1I0FWV2_9FIRM Transcriptional antiterminator OS=[Clostridium] sphenoides JCM 1415 GN=SAMN02745906_0760 PE=4 SV=1 ------ECRILVNQTYKNWQEAIDAAGGLLVATDCVLQSYVEDMINNIKEFGSYitIGNGIALPHARNKN--NVKKTAFSLITLKKPVVFDNGKE-I-DTVISfCNVAGNDYTTALTALMELSENQSFLDYKKKVETPSQLLDYIKK-- ->tr|A0A0R1UUJ1|A0A0R1UUJ1_9LACO Uncharacterized protein OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL002133 PE=4 SV=1 ------KKLVFTDIAITDFIELIKWMSHQLYLMGYAKKGIAESAIKREQLSKTSFK-DYAVPHAQP---EFIMKPVVAVCILRQPIEWGANLVSI---VFFFGMTDTLSqKeidPIFDDFYKIVNSQRSLDSLIKAKTNHDLFIRLIGE- ->tr|A0A0R2HD20|A0A0R2HD20_PEDPE Uncharacterized protein OS=Pediococcus pentosaceus GN=IV86_GL000421 PE=4 SV=1 ------SELVFLDKKLLTKEEVINFIGEQLVKLNYAKKGVSESALERERLSSTAFE-KYATPHAKA---EFINKSAIVFIRLKNEINWLGQNVRF---IFFICVKNETPNqldQIFDTLLEIIEENKEHkEHTLKNESPDNIVCYLKEG- ->tr|K2PSP3|K2PSP3_9LACT Transcription antiterminator, BglG family OS=Lactococcus garvieae DCC43 GN=C426_2091 PE=4 SV=1 ------KEFIFLDEKINTIGQAILFLGQKLIAKGYAKEGFIESCLEREQLSFTSLD-SFSTPHPLnI---EEVNKPVIAFMRVKNELIWGKEKVKY---IFMMCVRDRSIKeleRIYSALLKIIDSPDQ--EILLRGNLDEIFDYLANN- ->tr|A0A1Y4F812|A0A1Y4F812_9FIRM Uncharacterized protein OS=Blautia sp. An249 GN=B5F53_05340 PE=4 SV=1 ------EENVILDREAKTKEEVIRILTKHILTENGVTdeTEIVKAVAQREKLAFTGIGKRTALVHAVT---AGVKETKAVFLRTVSPVDWAKGKDYPEeakmiRIALLLLIpekeQRGEDVEKVKQLVLKLGKKENARRLLEVSTKQEVLKILNG-- ->tr|I0IBG4|I0IBG4_PHYMF Putative antiporter OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_04430 PE=4 SV=1 -----SEKLYVDELRTDNARGIIAELAERATATAGLPAaEIAESAWRRERLFSTGLPGGLAIPHARLA---GLSRPMVAVGRSRDGVDFDATDGSRARLICLLLSPAedpTAQVELLRAVGETFANKETRAAALDATGYTQFRAALIV-- ->tr|A0A168HYL4|A0A168HYL4_9BURK Uncharacterized protein OS=Pandoraea pnomenusa GN=A6P55_01740 PE=4 SV=1 -----EEKDFLPNVE-----RILVAVDGsangrFAAWIAGLTAgvrGTLTTVLAPSAAPTdgGRTAREVAEPARSPA---RPAKDKSAIGADEEGAGRDAYDIALAAAQIAIPAHRgppAsrttpAPIRRARPLASCYASAPARRRRRRRTCPTAPSRKAT--- ->tr|A0A0W8G8H2|A0A0W8G8H2_9ZZZZ Uncharacterized protein OS=hydrocarbon metagenome GN=ASZ90_000699 PE=4 SV=1 -----KAETFVSPLPATGPRRIVSLLTRTAARCAGLDEnAVLAEVRSREKRLSTALGRGVAAPHARIP---GLEHPVCAVGVVPEGVGMDSPDGLPVNVFFLVLSPQaddGAHLAILADIARAARMPHFASRAARTRSIEEFLRLLEG-- ->tr|E8RD94|E8RD94_DESPD Sodium/hydrogen exchanger OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_0718 PE=4 SV=1 -----RFGLFLPELRADSIKGVIEEMTAVVGQVLGGRLepyVVSRVSCAPEDVACAAIVNDVLLLAAGVD---HISQPYVVTGLSTQGVGLSFMDTQRAHVVFLILSPKndpAIRGDMVAELSLLYRDQAMIDQTLQARSFTEFLALIRT-- ->tr|A6DSK5|A6DSK5_9BACT Probable Na/H antiporter OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_21970 PE=4 SV=1 -----GRGAFVADLKHPAPAHVIKDMVLQLNIDHEVQADIIQSTISREQLMSTGLEKGLAVPHCRTD---LVKKPILLIGLHESGADFDCFDDGKAHVIALIITPLsdpESQLELISVLASHFSSKEEMVKAMTCKSKVDMQAILNA-- ->tr|I6ZT81|I6ZT81_MELRP Putative Na/H antiporter OS=Melioribacter roseus (strain JCM 17771 / P3M-2) GN=MROS_2022 PE=4 SV=1 -----KKEAVfIADDSISDKKELIRKLSAKVAEVHGLNKdLIFDEVWKREETISTGLENHLAAPHARCD----VKYPIAGLAVHKKGIDFDSLDGKPARLIILLITPKdkpELQLEMLSGIAQKLGKSDIIDYIINLNSKEEIIKTINR-- ->tr|U7VBW2|U7VBW2_9FUSO Uncharacterized protein OS=Cetobacterium somerae ATCC BAA-474 GN=HMPREF0202_01111 PE=4 SV=1 -----VYPGIK--LEAQYKEQAISKLLDLLK----LEYreaNILENVLDREDIVCSGLQNSIAIPKGNIE---DETKTKIIYARLENPINWNSLDGKLTKNIFLILTSReeqENQIKVVKKITNFSKKCDEIKGLDELATEKNIEDYITK-- ->tr|A0A1F6GDD9|A0A1F6GDD9_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_12300 PE=4 SV=1 -----SAKTFVPKMQVNDCWEAIELLSRVAALQAGLDPlEVIEAVKSREETMSTGVAKGLALPHGRLP---KLKKPIIALGICSQGVDFHSVDNTPAYLIILILNGSqdsGVQLRLLADAARIIKEVENLEEVKNITEFSELLHWLRI-- ->tr|A0A1J5FUT6|A0A1J5FUT6_9BACT Uncharacterized protein OS=Ignavibacteria bacterium CG2_30_36_16 GN=AUK34_00745 PE=4 SV=1 -----SPSNFlYSSAT--DKETLLIELANFAAPKVKIPAkEILQKVMEREKQGATGIANYLAIPHAKIK----TNKPYVLTAKIKEGINFGSVDGINSRIVILLLTPEnknELQLQLLAETAKKFSNKEKIEELLSIDDKNIFIEMLKQ-- ->tr|A0A1J4TUW5|A0A1J4TUW5_9BACT Uncharacterized protein OS=Ignavibacteria bacterium CG1_02_37_35 GN=AUJ54_14570 PE=4 SV=1 -----QERFVfFTNES--GKEKIISRLVEVASKELKLEKeVILREVMSREKNLPTGIANYLALPHAKIK----IKDPFIGIAINKRGVNFDAADGLPCKIIILLLTPEnnnEIQLQLLSEIAAKFRSKEQVEKLLALLNARELCAELKK-- ->tr|A0A1F5P5M2|A0A1F5P5M2_9BACT Uncharacterized protein OS=Candidatus Delongbacteria bacterium GWF2_40_14 GN=A2Y39_02215 PE=4 SV=1 -----MRDGIIPELLGTTKNDIIAELCSKVTPKLTG-LtcgEINTTVLEREKLMGTGMARGLAVPHARID---GLKNPVIAFGRSAPGVDWDSADGLPAHFIFMILLPAkdeSKQIQILAGIAKTISDPVYSENLLRMNDQERIYQSLKK-- ->tr|A0A1G0W9G7|A0A1G0W9G7_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_38_69 GN=A2X47_01805 PE=4 SV=1 -----SSDSVLNDLKAANREEAIKELCATVSGRLPGSLrnkCIAAAAISRENDFGTALGEGIAVPHIHLA---GLRHPILMVGCSRNGIDWNAPDGQLVKYIFFVLSPEgahDIHVQILSTIAKAMMKVQNKLEMDNSKDDSQLYDSLKK-- ->tr|A0A1G1LLX8|A0A1G1LLX8_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium GWA2_47_8 GN=A2Z88_04395 PE=4 SV=1 -----AAKNVFLDVVGQTKEEVITNIASLLAERNIVQDenMIREAIWEREKLMTTAIGDGVAIPHARLP---NLKVPILGFFRLRHPVDFNSPDNKPVQIVFLELTDRdddGMQLNIVSQIAHFLASPHSIRRLLQCQREEDVYHVLSF-- ->tr|A0A1V5Q2C8|A0A1V5Q2C8_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin345 GN=fruA_4 PE=4 SV=1 -----PADALHLDLRARDRAGALRELCEVAALHTPG-LdlaAAHAAVAAREEAMGTSLGHGVAVPHARMD---ELKSAVVVSARSKEGIDWNAPDGQPAKLLFLVLTPThdaEMQIHILAKVAAALRTEEQRKALFEAPTPEVFYRALCR-- ->tr|A0A0T6Y7W4|A0A0T6Y7W4_9RHIZ Uncharacterized protein OS=Sinorhizobium sp. Sb3 GN=N183_28220 PE=4 SV=1 -----FENNLMLGVPAKDKRSVVQIIASHLALRtGMPFNVIFDGLMDREALGSTGFGDGFALPHALISDLSTPAR---VLVTLREPIDFDAaddEAVDIFVAVIWPQEQHDGFLQHLAKLCRLFRSKKLLVALRSARSETEASILISA-- ->tr|A0A1L3SUA0|A0A1L3SUA0_9RHIZ Uncharacterized protein OS=Mesorhizobium sp. B7 GN=BSQ44_17030 PE=4 SV=1 -----RPQDVLMRHPAQAKRPLLEAMARQLASRtGLTLVSVLSALLSREKLGATCIGQGIGMPHAMPGGLGEPAA---VLAVLEHPIPYDAsdeQCVDVVLGVVWPREGSTEFLNALARFCRHLSRPQVLKKVRAAMSAEEVLQHLGQ-- ->tr|A0A1Z2EZL6|A0A1Z2EZL6_LACCA PTS fructose transporter subunit IIA OS=Lactobacillus casei GN=BGL52_01435 PE=4 SV=1 -----VTTDVHtdVA-VPADKHAALGTIATILSTNrPISADELRDNLIAREDESSTGFGNGVAIPHAKVNGLTEPFV---GVVTFKQPVAWDSldgQPVSIAIVLVMPDQNgaDKLHLKMLSKLARKLMDDDFIKALKDAQHDGSQmTKVLDQ-- ->tr|A0A173VYL9|A0A173VYL9_9FIRM Probable licABCH operon regulator OS=[Ruminococcus] torques GN=licR_2 PE=4 SV=1 -----SEEFIIFEKKAKNRKDVLKRACQLLINKGIVQSEFARDVLEREKVEATAVGCNIAIPHGKP---EHVNRCQILVIRLDKPIEWGERMADMIF----LLAINFDSVNTtkafFHDFTKLLNENGATDRLREAASPHELCAAI---- ->tr|A0A1I0FIB3|A0A1I0FIB3_9FIRM Transcriptional antiterminator OS=[Clostridium] sphenoides JCM 1415 GN=SAMN02745906_0486 PE=4 SV=1 -----RPEFILLDVETVSKNKLIEIGFQVLRDYGCVTDRYYQEVLYRETISSTEIGNGVAIPHGIE---NSVLMPAVCMIRLKQKIDWGSAPVDIIF----MLALNFNDGETtrrfFKSFYEKAGNENIIRLLRTVRTEEEIMEIL---- ->tr|A0A099IAS6|A0A099IAS6_CLOIN Uncharacterized protein OS=Clostridium innocuum GN=CIAN88_05525 PE=4 SV=1 ---------LFYLYDTLNKEELLSKMCSHLLDLHYVAGNYYDAVLEREKYSSTYIGNHIAIPHAV---FPLAKKTTISICIMRNPVRWDNE--HEIRLVFLLSIKFSDsrYMSDLYNLFaEMVENSELAHKCIACTSYDEIIQLL---- ->tr|D2U2R6|D2U2R6_9GAMM Putative transcriptional regulator OS=Arsenophonus nasoniae GN=ARN_28930 PE=4 SV=1 ---------YFIILnEKISQEALFKKICKKLQADGYVTSDFYPSLIERESIVSTLLGEGIALPHSL---GLLANKTVVVTIISPQGIEWNAetK--EVANVIFLLAISKADyeEAIAIYELFvTFVKE-KATKRLINSRNFNDFQVIA---- ->tr|I0R2G5|I0R2G5_9MICO Uncharacterized protein OS=Candidatus Aquiluna sp. IMCC13023 GN=IMCC13023_05300 PE=4 SV=1 ----FGAGSIVAQDASPSFADAVSQSVSLLVASGKAQLSYVDEVLESLKTLGPYfvIAPGLALAHAK--PSDSVPAPGMALLKLAQPVISG-SANDPVSLVFSMCSPNaSEHMEMLADFGQIMSTDQVMTNLLNASAVSVIEDILF--- ->tr|R7G7I7|R7G7I7_9FIRM Putative phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Eubacterium dolichum CAG:375 GN=BN631_01564 PE ---------ICCNFRAKRRDDVLEKGAQMLHQQGYCTDNFYNILLHNENFVSTAIGNGVAIPHG---YKKEILRSGIAVIKLERPIDWDES--EKVELVFVLAIDldNPqEIYKFFSNFYVLIDDKERLEQIKLAENSKEVMAVIE--- ->tr|A0A1Q9JV28|A0A1Q9JV28_9FIRM PTS sugar transporter OS=Anaerostipes sp. 494a GN=BHF70_10670 PE=4 SV=1 ---------ILTDVMTATKKETIAEASKLLCQEGCLEEDVTEKVFELEERRPTTIGNQIAMAHV---YKEHVAESGIVLLKMKYPVQWSNT--SKVKLVFFIAINfeNSeEIVELFKFLYSLIDNKKAIEKIIGAKEPKEIYEILI--- ->tr|R4I1J2|R4I1J2_9GAMM PTS system, nitrogen regulatory IIA component OS=Serratia symbiotica str. 'Cinara cedri' GN=ptsN PE=4 SV=1 ------IKCTKIIIHFINKKWALNIISTLASTtLQIQQLIIFNTVLTNEYIENTNIGNSITISCRALK--NNILKTVSIFIHLKQPITFNIIDNQRVDRLFTLLKRtnqCKTYLHILFLTIKLLANNTICCYLRTE-------------- ->tr|G5ICP5|G5ICP5_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_01230 PE=4 SV=1 --FQLMSERItILKCDCRSKEEVIELLGGRLYREGFVDEGFVESVFVRENLAPTSIGYTFAIPHA---YMGHIKKQGIGLMTLKHPIPWDNGEKVQIVLMLSIDVKSSDAFKIIFSqLADLTKDLPAVEQILK--------------- ->tr|A0A174J4C9|A0A174J4C9_9FIRM Probable licABCH operon regulator OS=[Eubacterium] contortum GN=licR PE=4 SV=1 --KKFLNSSIsIMNCDLKSKEEVIKLLGGRMISEGYVDEGYIQSVFEREELSETSVGSLVAIPHA---FEGHIRKQGIGFMTLQKPIIWGS-EKVQIVFMLALDAKVENNFQRIFSdVLDLTRNIKDVEQVLR--------------- ->tr|A0A1E6VIK3|A0A1E6VIK3_LISMN Transcriptional antiterminator OS=Listeria monocytogenes GN=AJN46_07955 PE=4 SV=1 ----------FPKQNFKSKEEVITFLCEQLTAFDYCDSDYVSKVFEREQLSSTCYGNYYAIPHAI---QRSAKKNAVAVCALDKPIDWGGNRVKLVLLLTMKEERDNSFEELFGQLVTILNERSFVKKLAKQEDFQQFIELC---- ->tr|A0A1V8ZKD0|A0A1V8ZKD0_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus GN=BH739_12400 PE=4 SV=1 ------PNLFFMNEESISKELLLKKMTNKLAEEGYVSQDYFSTLWKREQETSTCVGNKTAIPHGAMKE---VNEPKIAVCTLKTKMQWSKdEEVQL---IFLLAAKMNTKvnIDKTKtfysDLIRITENEEIFEKLINSQDGVKAY------- ->tr|H1B496|H1B496_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_00029 PE=4 SV=1 -----------FQDSCENRRSLIHKYCTYLEDNGYVTEAFEASVYDRIQYSSTAIGRGVAVPHGT---KKAVKNSVILIIKLDHTITWDDQLVDL---VFFA-AIGEDISTeyskIFRRIVRIVSDDEQTHMLKSCNSLEEIRKY----- ->tr|A0A242CWE9|A0A242CWE9_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_003754 PE=4 SV=1 -----------YRDQLSTKEELITTYSALLEEKGFVDKDFGPSALTREQTIPTTLGRGIALPHGS---SDHVIHSCILIIKLEQTIEWSGHQVDL---VFLT-AVNQKDVEfhrsFFEQLFKIISNESLLNEIKSIVDVEALKKI----- ->tr|H3NPA2|H3NPA2_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_01163 PE=4 SV=1 -----TKEKILKLKEVENWEEAIKKASQILIDNRSINKQYVEDIIYNiNKIGPYvVLVDGVALPHAQ--NHNSVYKVDASLMIVEKPVEMKGKKV---DIFIVISVlDNISHLKMLATISDILDNKNNIEILRRG-DYREIRKLLL--- ->tr|A0A1S9C336|A0A1S9C336_9FIRM Uncharacterized protein OS=Epulopiscium sp. AS2M-Bin002 GN=ATN32_03240 PE=4 SV=1 --------LILLNNNAKTKDEVIKTLVNKLYKNGKLSSeeGFLKAVFDREKLSATGLEGGLAIPHGKSNFVKeasfAVMSTKN-IVG-WESLDPDNEVKYIFLLAIPEAAAGDTHLELLSELMTRMSDEEYKEKLFASKDVKQFMTNLD--- ->tr|H3KHB0|H3KHB0_9BURK Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (Fragment) OS=Sutterella parvirubra YIT 11816 GN=HMPREF94 ----VTLDAVRLDIAAASRKRLFEEASLLLESAyGVAHSEAFDALIARERLGSTCMGAGCGIPHGRIEGVTEP---CLVVLRTAEPVMLDAPDGRGVQLFFCLivpEGDSSEYLGILRECAAIMNDRPMRQALMSAPDATEVCRLIHE-- ->tr|A0A227KED5|A0A227KED5_9BURK PTS fructose transporter subunit IIA OS=Turicimonas muris GN=ADH67_11000 PE=4 SV=1 ----LKPDNILLGISASSKKRILELGAQTLSLLyHLDKKAIFDGLNARERLGSTYLGYGLAVPHCRMKDLDQP---RALFIRLNDRLENN-TESEPIEAFFFLlvpEEETDEHLQILAQISEIFSDKQEREKLKEASTVAEFAEVINQ-- ->tr|R3TT34|R3TT34_9ENTE Uncharacterized protein OS=Enterococcus phoeniculicola ATCC BAA-412 GN=UC3_01566 PE=4 SV=1 -----PVERIKVTTRKFTFQEAIQAVGEPLLKDKIIEQQFIDTIIQKY--DERYpyfvIAPQIAIPHAGYN--DGVNQLGFSLLKLKHPVRFSPR-LN-VSVLLMIAPIdNKKHQKAVQAFYDCVSDEANHQELLRQQTPEQLKKFF---- ->tr|A0A1L8WBQ1|A0A1L8WBQ1_9ENTE Uncharacterized protein OS=Enterococcus pallens GN=RV10_GL001463 PE=4 SV=1 -----PIDHIQVSNDPLSLEEAIVLCSQPLVKNRIVEASYAERIVANY--PKGEsyfsIAPKVALPHTTGM--NDVHSVGMSLLKLKEPIYFPNEKRW-VSLLMVVAPLnNDMHINAVTQFHKIVLDDKNVERLLKCREPEELRDII---- ->tr|F5YB74|F5YB74_TREAZ Fructose-specific phosphotransferase system, enzyme iiabc OS=Treponema azotonutricium (strain ATCC BAA-888 / DSM 13862 / ZAS-9) ------KDAINTDLKSKTKQDAFEELLEAIQNVQPelNTEEALEALTARESQMSTGIMPHVAVPHALCPSARGAI---GAIGISRSGIDYNALDGSPVHLIFMLLanpESCSQSLRVLKHLAQLLDTPQFAADLIRKRTVEEIQGMLNL-- ->tr|A0A1G0Z9C0|A0A1G0Z9C0_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_09980 PE=4 SV=1 ------AGRIKLHVEAEEKDEVFDELITRLVGTDHagRKDEFIKIIRERENIISTGFKDGIAIPHGRIDDLDGVV---GVLGISDKGIEYGSLDNNPARIIFMFLsskSRQDEHLAVLKRISRISDNADFRKDILLAKTPQSANKILKE-- ->tr|A0A1G3MHV8|A0A1G3MHV8_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWC1_61_12 GN=A2004_01695 PE=4 SV=1 ------QDRICLDLVDTAKPELFAVLVSKLNQTLFrplDFMMACNALQVREARLSTAIGNGIAIPHAKITGINEVL---GVVGISRTGITYKASDDKPVQLIFLLLspaDTSDKHLHALKLLATALEKTTLRDDILAGSSDTALIwRCLQA-- ->tr|A0A1F9FVT7|A0A1F9FVT7_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_44_16 GN=A3C46_04810 PE=4 SV=1 ------PESIVVPLKATTKLEVLEELVTELSKRTGiaNPKSLLHAIEEREACSSTFLPMGVAVPHARVPEVSDIT---MIAGIAPEGIMDAG---dpssltAHVFCLFFSSteeKEFGKHLKLLARIAAVFSDPDFVAKISHMTKPDQIFSAIQK-- ->tr|A0A1Y1S1X3|A0A1Y1S1X3_9SPIO Uncharacterized protein OS=Candidatus Marispirochaeta sp. JC444 GN=B4O97_04710 PE=4 SV=1 ------PDSILL-LKEAGKTDTLGQLVSSVPEAASslSGKEILEKLLAREELMSTGIGLGLGIPHIRAAGINTPV---LRIGVQPKGIpDYESIDGLPVKILFMILlkeDQQREHVALLSEIVSLMKMEHLRNQLAAISSAQQGYDLLRD-- ->tr|F7K891|F7K891_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_57FAA_CT1 GN=HMPREF0994_01864 PE=4 SV=1 ----LREENILLDVCCTDWKEVIQKATEPLLAAGSIDARYIDAMIRSYETNGAYFvyCPGVALAHAG--PEDGVRFFGLSLIRLKKPVSFGHRQHDPVTWCICLAIQeKDEQIQEVLRLMNLLGNPEKRPELDAIACSGELLQYIM--- ->tr|A0A1C5L5N9|A0A1C5L5N9_9CLOT Ascorbate-specific phosphotransferase enzyme IIA component OS=uncultured Clostridium sp. GN=ulaC PE=4 SV=1 ----LKKDHIVLDIPCTDWRDALSKAAIPLLEKGEIQPQYVDAIQHSVDVNGPYFvfCPGVALAHAA--PTDGVLEFCCSIYRPQEPVSFYHTQNDPVSLIIMIGITdVNTQVRYVSALMEVFRKKEFMERILHAQTPEKLITILL--- ->tr|A8RW19|A8RW19_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_04455 PE=4 SV=1 -------SLVYHFPERTHKKEIISFLCARLAEAGYVTKDYEQTVLDREETTSTVLELGVAIPHGAAF---CVCRPVIAAAILEEPVDWGRDRR--VDRIFLLALNlderfkAkGQIIRFYSAIVTLLDDKEAYEEFHSLRGQEEIAGYLN--- ->tr|A0A1W6WC75|A0A1W6WC75_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium CPB6 GN=B6259_00845 PE=4 SV=1 -------RFVYFC-DHAEKTALLQTMCGDLEEKGYVLPGFNESVLQREKAASTQVGRRIAIPHGSTR---YVVRPIIAVAVLKNSIPWDRQDT--ADFVFLLAIQpdsllhMkPQMMKFYKVLSALIDDEKTLNEVKKMTDRQEFADYMN--- ->tr|U7DD75|U7DD75_9BACT Uncharacterized protein OS=Chitinivibrio alkaliphilus ACht1 GN=CALK_0603 PE=4 SV=1 --------------ESEDKVSAITELAEAFCEiqKCDKAKRLIKDIIAREEAASTFVGQGVAIPQAVMNMKdEYAIMVG----RSAIGIDYGAVRNARAHIIALVISKknidDDDTFEVLSEISTFFRNET-VNKLIRSAEVERLSEVISE-- ->tr|D5SU40|D5SU40_PLAL2 Uncharacterized protein OS=Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290) GN=Plim_1190 PE=4 SV=1 --------------TAKTRQGAIRALVQAANWddDGINPENVLEAIEEREAAAQTLVANDFALPHAFIDwDGDFRIVLG----RSKTRVDYGGPAGVNVQLIVLLVIGrrlQQTHVEVLAALAELLKSPDFRQNLIDAKDIKAIDLLLMT-- ->tr|A0A1Q6UHC2|A0A1Q6UHC2_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium CAG:312_58_20 GN=BHW65_09695 PE=4 SV=1 --------------SAADFSEAVGQLLACIPDsilGGADRADVLANLIEREKSISTYLGDGICMPHTRVVgLKqKYVFAVG----RCSEaGINFEGLEDyRQTRILFLMLSDekVDNYLSVLSNLAKIFSSDDVCGRIKSSPDIAVFREAVMG-- ->tr|A0A0J7HU55|A0A0J7HU55_9BACT Diadenylate cyclase OS=Chitinispirillum alkaliphilum GN=CHISP_1305 PE=3 SV=1 --------------NTNSKDQVFKHLIRLITDefPHTNYTEIMTLVQERESLISTRVSDSIALPHARIPgFPGTVAAVA----LSKKGILYDSLDDTKIKLCILIVGDGNNHLEALSWTAKRLSDPDRFNSILNASTPQKIVSILKG-- ->tr|A0A1V6E2H1|A0A1V6E2H1_9BACT Diadenylate cyclase OS=Verrucomicrobia bacterium ADurb.Bin122 GN=BWX86_01135 PE=3 SV=1 --------------SSLDLEGALRELLAVSVSkfPDLKPEPLLRGILARESTMTTYLGLGVSLPHVRVKMKrRYILAIG----RSRLGLRHDGAREeDRIRIVVMLIAGetARDYLQVLASLARLLKEPDLVQSLSAAPDLASIYDRFVG-- ->tr|A0A1V6D3M7|A0A1V6D3M7_9BACT Diadenylate cyclase OS=Planctomycetes bacterium ADurb.Bin126 GN=manP_1 PE=3 SV=1 --------------QASSKDEALKELALALCRhdPVLDVETVMRAINDREHAVSSRIAPRIALPHALVSgYNRQTLAVG----YSPAGISWDSPGGGGVNLVVMSVCGealADAHIRMLAELAGTLQDENTLERLTGAGTNWQVYEVLRG-- ->tr|A0A1Y1S425|A0A1Y1S425_9SPIO Diadenylate cyclase OS=Candidatus Marispirochaeta sp. JC444 GN=B4O97_01265 PE=3 SV=1 --------------PAgqgVSKDEVIRRLCRAVAAdlGGMDAAQVESLVQKREASLSTRLSPLLAVPHAVIPhSKDNRMAVA----VIPDGLDWDSDRDNPVRLVMLLAGGREKHLKLLSEMAAVLQNEELLDRLISALNAAELISILRQ-- ->tr|S6CK95|S6CK95_LACCA PTS system galactitol-specific IIA component OS=Lactobacillus casei subsp. casei ATCC 393 GN=LBCZ_2702 PE=4 SV=1 -----DPSFVKHFLKAVTFPEVIDQLSANLLAKNLVTTAYLQAVKDREEKFPTGLPTepiGVAIPHTDAQ---FVKTNAVSVGILSTPIMMmvmGSENDKVEvSIIFLLSLgQSNKQLNILKRIMTVVQDQEMLNEFKTASDARV--------- ->tr|W7ZBP0|W7ZBP0_9BACI PTS system, galactitol-specific IIA component OS=Bacillus sp. JCM 19047 GN=JCM19047_483 PE=4 SV=1 -----DASFVYLNQSIHTKTELLTALGTQMETSRCATSGYTRALLQREQEHPTGIPFqptGVAIPHSDET---FIVKSKISLLTLRRPIYYeqmGTTSTFIPvSVIFLLGIkNDQAARKTVLTLLEKIQNRHFLSTIRSLSSPYE--------- ->tr|L5LB69|L5LB69_9MOLU PTS system, fructose subfamily, IIA component domain protein OS=Mycoplasma feriruminatoris GN=fruA PE=4 SV=1 -------NTSFFKQEFKTKTQIIDFLASKLKEEKIISKktVFLNAIKTRENQESTAIGNNVAIPHALN---SVVLKPTICFMSLKTPIKWNSNDNQLVDLIFMIATNdsdTNDHMDAIAGLSSKLLDDNVLEQLKQIDNFDQLIELFSD-- ->tr|A0A0W0RWS6|A0A0W0RWS6_9GAMM Nitrogen regulatory protein OS=Legionella birminghamensis GN=ptsN PE=4 SV=1 -------DCVNVDSSSKSKAAVFQKVSQLLSDNfsELNREELFSAYWKREALGSTAIGHGIAIPHVRVPGLNRV---RACFIRLLHPVDFCAEDRQLSDLIIALAVpenQSEYHLKLLREIIVQFSDQEFCRICRGLTCEKALFNLLIE-- ->tr|A0A1M7YBR3|A0A1M7YBR3_9FIRM Lichenan operon transcriptional antiterminator OS=Anaerocolumna xylanovorans DSM 12503 GN=SAMN02745217_02535 PE=4 SV=1 ----------------KNKNDAITKMTQNAISLGLAKESLTENVLQRESLSDTGFN-GVAVPHSL---REDVMKSFISFAICDTPMEWGAKQVYIIA-LIGVNQDSRKAFtEVFDFLVDVLSEMQNVKELASSADYDDFFQKLT--- ->tr|A0A109UHI4|A0A109UHI4_9FIRM Uncharacterized protein OS=Erysipelothrix sp. LV19 GN=AOC36_10080 PE=4 SV=1 --------MFFVNEAPLTKEAVLNDLITQITQHAKLPKNFRALVWERERFSTTDVLPHIAIPHPNRLVSD---DSFVACMVLDKPINWGNHE---VSILFLpcLSKEDSEKYAFIyDWIIKLSNSKETILNIQNNKTYESLVNGVlK--- ->tr|B0N4Y4|B0N4Y4_9FIRM Putative licABCH operon regulator OS=Erysipelatoclostridium ramosum DSM 1402 GN=CLORAM_01695 PE=4 SV=1 --------MVLTSINADTKEEAISFIINSTNYD----KNIIQEIIENDKVANHELDNMISILSLNGiSANN---QTEVIIGILSKPILWNEKR---VQLIIVplIGEPINSKILNLyHELAYMIKNPLYVKRIIRKKTYEEIIAIFE--- ->tr|G1VXC7|G1VXC7_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_04658 PE=4 SV=1 --------LFYTDITGSDRTEVLCSMIQKLKKDIDLPDDFLELILERESFAATDLVNGVALPHPNRPVSA---QSFVSIGVLKHPVLWETKH---VQIVFLisIAPAQEQTISVFfEMLSDFVTQEKKIRQFLKKPSYDYMIQLIC--- ->tr|E5VHL5|E5VHL5_9FIRM HTH domain-containing protein OS=Lachnospiraceae bacterium 5_1_63FAA GN=HMPREF0996_00524 PE=4 SV=1 --------LFYDNIKGETKEEILFEICKRIPEKYGIPSDFYEGLLRREEITGTDLAKHVALPHPYETTSD---ISFACISVLDHPIRWTRQD---VQVVILmaVAEDEQRDLTNFlQLISEFIANESAVLQLVEEPDFTTFVNLLS--- ->tr|A0A173V7E4|A0A173V7E4_9FIRM Probable licABCH operon regulator OS=Faecalibacterium prausnitzii GN=licR PE=4 SV=1 --------LFFPHIQAGTREEALRQICHQMAQVYPMPeEEFCASVLAREQMGGTDFGNNVAIPHPEECFVK---ENVVCVAILDKPIRWSANT---VQLVILaaIYDSASAQAQKFyQLTSSLISDRVRVKRIIAKQEYEHFMKLLL--- ->tr|C5EFX5|C5EFX5_9FIRM HTH domain protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_00820 PE=4 SV=1 --------RFLSHVPVGSKEDVLKYICDVIEKQELVDNDFYDLVLERETYIQMDYGNMITLPHPNQIASE---ESFAYVAVLERPMVWNNLP---VQVILLtsIGRKGDKekERQRFyETTARFALSREAVSQLIQAPEYEVLVRQLK--- ->tr|A0A139TBW2|A0A139TBW2_9FIRM PRD domain protein OS=Candidatus Stoquefichus sp. KLE1796 GN=HMPREF3037_01820 PE=4 SV=1 --------LFIVNLNCKDRKEIIKEMCHTISLYEDIPQTFEKSILEREAITSTEFGNHVALTHPLEPLSQ---RTFACVAVLKDAIIWKEKE---IKVVFLisIEQKKNKNIQDFyKMTSKLLMSEKYMNQFIKNPTFEDLMTILS--- ->tr|E7GFH4|E7GFH4_9FIRM Uncharacterized protein OS=Coprobacillus sp. 29_1 GN=HMPREF9488_03517 PE=4 SV=1 --------LVLLQQTFQTKEDILNDMCHKIENIYSLPFSFQKFIEEREDLSSTEVGNLVAMPHPSSLCTE---QSIVMIMTLKKSILWKNNY---VKYIFLvsGNKNSKEECEFInENIIDLIMNNQWLQELDKISSYEELIHIL---- ->tr|E7MQ19|E7MQ19_9FIRM PRD domain protein OS=Solobacterium moorei F0204 GN=HMPREF9430_01544 PE=4 SV=1 --------CFIPNLKAKTKEEALRVMSKRLMQKYEFKEDLYDSVIRREQMASTDFCYKTAMPHTDKLISE---KSHVCIGILKEPIIWDENE---IQLIFLvsVGKDRK-ESQEFySLISKFVLNEKMIDQLINTSSYEIFIKTIS--- ->tr|B0N173|B0N173_9FIRM Putative licABCH operon regulator OS=Erysipelatoclostridium ramosum DSM 1402 GN=CLORAM_00434 PE=4 SV=1 --------LFFTYESFSSKEEAIHEIINECKKSYDLPADFEQYVLQREALATTEFNDLIAFPHSNKPVSN---ATFVAVTILKKPLLWKKHK---IRIILLsaIENKAIKELDDFyKIISNIISDSTIQWNLINNPNYQYFKEIIE--- ->tr|A0A1C6ELB0|A0A1C6ELB0_9FIRM Probable licABCH operon regulator OS=uncultured Eubacterium sp. GN=licR_8 PE=4 SV=1 --------MVFWS-SSDDKNEILKHMCENAVQNYNIPDDFFHYVMKREDIGRTSFGNLITIAHPIHPIGQ---ESFVGLTILDHPIDWDGEP---AQLIFLlsMKESGENKMKDFyKAMTKLVNNTHYIELLTKTKNYDEVINILK--- ->tr|A0A1C5MHM9|A0A1C5MHM9_9ACTN Probable licABCH operon regulator OS=uncultured Collinsella sp. GN=licR PE=4 SV=1 --------WFDPHLDAETPHEAICGLAELMVERAGAPAELVELALERESAASTAFGSGLALPHPIRSLPG---PTKVCAGIPNRPIRWGDKD---VELVLLvaIGDDGR-nALDWFfSRMAELLSHEERVKRIVDDRSFEVMMQEIA--- ->tr|A0A1E8R8Y9|A0A1E8R8Y9_9FIRM Uncharacterized protein OS=Anaerococcus sp. HMSC065G05 GN=HMPREF2852_02660 PE=4 SV=1 --------LFFNIKENCNHKDILDFLSKKVNKRTGINsKIYYKELIDREELASTCFENKVAIPHPLNSVCN---ENFISVLINKNSIKWKNQK---VNIVILinINELIDNeIVENFyKILSEYLTNNDKILKSMQAENLEEFLKEFL--- ->tr|A0A242K5Y9|A0A242K5Y9_9ENTE Uncharacterized protein OS=Enterococcus sp. 9E7_DIV0242 GN=A5888_002665 PE=4 SV=1 --------LFFENIDLSTKEEVLRFLVAHIADS-DTQEHYFHSILQREQLGATEYGNQIALPHPLEPVGD---TSIVAALSLKKPILWQKKM---VRYVFLfsFSKQSEKDVLIVtDFLTELLFDINSLQQLKKNFSFPTFQTLWN--- ->tr|D1AJW2|D1AJW2_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0134 PE=4 SV=1 ------ENNIEILDRLESWSDAIKVSGELLIKQNYVTKDYIQEMKELVEKFGSYivVADGIAIPHGSIG--KNVIKDGAALLVLKEAVKFDDGE--MVNIFIPFATRGkKFHSKLLNEIFDIIKRKNLKDKILSLKTKQEIIKYL---- ->tr|A0A200IFR9|A0A200IFR9_9ENTE Uncharacterized protein OS=Enterococcus sp. 6D12_DIV0197 GN=A5867_001530 PE=4 SV=1 --------DLFVAKSSmKNKNQVLSLLCRRLEEKGYVDPAFERQVYRREEAAATAFQ-NIAIPHSV---QMDAIKTSIAVTISKTGIRWGKHTVYLVLL-IAINKADKQTfRELYESLIALFNDQPTIQEVRNCQSFEDFKKLIYS-- ->tr|A0A0E9FNJ2|A0A0E9FNJ2_CHLTH Probable licABCH operon regulator OS=Chlamydia trachomatis GN=licR_1 PE=4 SV=1 -----------IEHGHTDRLTVLQEMTKRLQLCGAVTPYFLESVLKRETMGSTEVGNGIILTHGFYEA---VKRTQIAFYKLDNPIFWNTQKVNFIV-LLAVAKVDAKNVMQMSWLYKTLNSESIIEQVHKCSCEKELYELLIN-- ->tr|L1Q846|L1Q846_ANAHA PRD domain protein OS=Anaerostipes hadrus DSM 3319 GN=HMPREF0369_00641 PE=4 SV=1 -----------VFHEQIDKIQILQEMSNYLRMCGAVTPRFFEGVLKRENMGSTEVGDGIILTHGFHED---VKRTQIAFCKLDHPIVWKTQEVDFIV-MLAVAKTDAKNVMQMNWLYKMLSNMEIVNKIRECKKDREIYETLIE-- ->tr|A0A0A1MQS9|A0A0A1MQS9_9BACI Putative licABCH operon regulator OS=Oceanobacillus oncorhynchi GN=licR_6 PE=4 SV=1 ----TAPSCIHLREKVSDWREVLSILNQSLVKQDVVEHTYETEVAQiiNEQEHHFIVAPGVAFPHLSS---TAIKKTGFAFMTLEEPISFGGTEEKVW-WIILLAAKdKIQHVTAVEMMLEVVNSKELLDKLRHERNIDVVWKWMLE-- ->tr|A0A162Q224|A0A162Q224_9BACL Uncharacterized protein OS=Paenibacillus glacialis GN=PGLA_16875 PE=4 SV=1 ----LPCTSIRLQLDSMDWESAIQMGCQLLSERSLSGLNYEERLVEmiDSNIHSFIIHDGVAFPHANMP--GDIRQTGFSLVTFREPISFGPLAHPVW-LIITLAAVdKEQHVGALSTLLDALNDEMFMTDLQQSSNSYDIWRSFRE-- ->tr|A0A0R1KDY7|A0A0R1KDY7_9LACO Uncharacterized protein OS=Lactobacillus paralimentarius DSM 19674 GN=FC78_GL000532 PE=4 SV=1 ------PELVFVNSNLQTRKQVLDFLCDKLEEQAVVRSDFREKMFEREKMYSTAIGGEIAIPHPIKFA---ANKSNVAFMQLKKPIVWDD-NDNKIQliFLLAINEEEYPKIQTLFSFLVDLqSDTRFYNAISKCKDSNEAMKVIN--- ->tr|E2SHC0|E2SHC0_9FIRM Putative licABCH operon regulator OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_00369 PE=4 SV=1 ------EQL-FINTTANSKEEIIHTLCMMLHQEQCIKDDFEASVLEREQRISTAMDGVVAIPHPLVMC---SLKSKIAVGVLQKPIAWS--EKDSAQiiLLLGLADDAKKDIEKLYDTFVAMtHNAPLQELLFHAGSLSEFLNILK--- ->tr|A0A242NLG6|A0A242NLG6_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=B6D08_00715 PE=4 SV=1 ------PENFyYFDTDKLSKKDLLVKMAVDLEKQNIVSADFVSSVLERESLQTTLINDVIAIPHSMTMI---ANRSRVSVAIFPNGIQWE--KDKKCNfiFLLAISKTDNEITDNLYDLILNLiDDKAMTKQLLKAYTFHEFKNLLS--- ->tr|A6DML2|A6DML2_9BACT Probable fructose specific permease-possibly phosphotransferase system component OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_160 ----LDEEHIITGLNAKNKWEALREMSYFLVKTNDIEidpEELLKRMEEREKEFSTGFGQSIAIPHCTVTDeesHDGKIR-G-MLAVCTPGVEFESMDDEPVEIIVMLATpesQREAHLEILSVLGRMLSDATIREQILKANCAASIYEIIHS-- ->tr|F4LRK6|F4LRK6_TEPAE PTS modulated transcriptional regulator, MtlR family OS=Tepidanaerobacter acetatoxydans (strain DSM 21804 / JCM 16047 / Re1) GN ------DEKLYFKNkGIKNKVNAIKFLGNHLEKMNICEKGFTESVLRREAISSTCFLGTFAVPHA-IELNA--KFTQFCVLIEEDGIKWDDN---NINCVFMIAVSKDDRkafMEIYSGIVQILCDKESIDKLIKAPDFSSFINHF---- ->tr|H1BBX9|H1BBX9_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_02712 PE=4 SV=1 ------SENLFFISeKINTKDLAIQFLAEQLKKDGSVNDTFIDNVLQRESLSPTCFMNSFAIPHS-FQEDS--IKNRIAILINKNGIQWNNQ---TIYAVFLIATSKNSIkrfnKLLFERIGYLF-SENNKQKYLAIDSYDSFIKYL---- ->tr|A0A0U9HG12|A0A0U9HG12_9THEO Lichenan operon transcriptional antiterminator OS=Tepidanaerobacter syntrophicus GN=TSYNT_8139 PE=4 SV=1 ------SSDLFLYTtKIKNREEAFKVMTKIMKEKGIIDERFITSLYEREALSSTGFMNSFALPHS-LEYNA--VCSKIFALVNPESIKWGDA---QVKIVFLIAISRKDRekvKPLFDFLTDIMIDEQKIYNLSKAMNFENFMQIL---- ->tr|A0A133L1Z4|A0A133L1Z4_BACCO Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bacillus coagulans GN=HMPREF3213_00215 PE=4 SV=1 -------AFIVLDADYKTQAEFFCASSAILKQREYVKPSFCKAVMEREALYPTGLAneyIQFAIPHTDAFHVEK---PFVFVTRLKNNIPFMHmgtTDIPVQaKviFMLGIK-NPEKQVGLLSDIMKCFNDGDFVRTILSIQDTHAMADYLK--- ->tr|W5SP83|W5SP83_BORAN Na(+)/H(+) antiporter OS=Borrelia anserina BA2 GN=BAN_0070400 PE=4 SV=1 -----KKENIILDLKATNKIEVLRELLGVIKVE----iDkeTILQDLMEREKLITTALKEGFAIPHLKTNLIK---KMHIAIGISHNGIDFNAIDKNLSHIFILILYPakeYINYPRILASIVGKVGS--NKKAMLKATTNKEIYNIIV--- ->tr|A0A1G1Q8F9|A0A1G1Q8F9_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 GN=A2243_07050 PE=4 SV=1 -----SSKALNVDLQGRSKEEILAELVELLIESKQLDasQkeEVVKDLLKRELMMSTGMQNGIALPHAKTIAVD---HVVAAVGISKEGVDFASLDKIPSKIFVLTLASkehPHAYLQSMSEISRFLSKEENRAKMIACTTRIQLFDVLS--- ->tr|A0A0F7E441|A0A0F7E441_MYXFU Uncharacterized protein OS=Myxococcus fulvus 124B02 GN=MFUL124B02_01000 PE=4 SV=1 -------EAICPSLRARERVGVLHELAGMMADEAGVpARELAVHLLAREQLGSTAMEGGVAVPHCRHARAGRIV-T--CLGIHRGGLAFGEPEDGLVRIYVGLVSPPdtgGLHLNVLSRIATLLHDVRVRDALMAAASPAVIRALLVR-- ->tr|A0A1F9UJQ0|A0A1F9UJQ0_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 GN=A2992_02965 PE=4 SV=1 -------QTVAFFPAGPSKRQVLGSLIGLFDLADPGa---ALKAILAREEAGSTVIAPGLALPHARITGIPRLR-A--ALGLCPGGIQYSHAVEEPVKLVLLFLGPAenmREHLAFLAGASALFQNSELVKRLLTLTSPKPVLRGLQE-- ->tr|A0A140DY33|A0A140DY33_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_24260 PE=4 SV=1 -------ENLFVRFdDPVTKDQVLDELCSRLTTAGISGPDLRESVRKREEISHTNLNDIFAIPHP---MTPEASRTRAAVAVLNHPVVWNDKG-SAVQIVFLLAFCKGEqqSIERLyDYLLEIVQSVPLQQSILKAGTFEEFQTLCL--- ->tr|R2S7W1|R2S7W1_9ENTE Uncharacterized protein OS=Enterococcus asini ATCC 700915 GN=UAS_00034 PE=4 SV=1 -------ASMFVINnQKTTRDTLINSIGNILEEQEVVNIGFTKKVLEREHIAPTNITDLIAIPHA---IDANIKQTKIFVYISQSPIIWRDD--KTVKIIFLLAVAEEDkeNLHTFfEYLSDLVENKKLQQKIGNSQNFEMFLSSLF--- ->tr|A0A1T4RE50|A0A1T4RE50_9ENTE Transcriptional antiterminator, BglG family OS=Pilibacter termitis GN=SAMN02745116_02562 PE=4 SV=1 -------EKFFFPKmNFKNKEEALSFLCNHFEN----GEKFLTSILKRERIQDTYIQNGIAVPHP---IDFYFKETKIAILSLEKAIPWNQSG-KKAELIFLIAPAKCDlkELDDFfEQLILLLNNRPLRRKIVQTNNFQELLTLFQ--- ->tr|A0A062XZH2|A0A062XZH2_9BACT Uncharacterized protein OS=Thermoanaerobaculum aquaticum GN=EG19_04805 PE=4 SV=1 ----FGPEHVLDQLTASTREEVIAEIVKFVAEKRMVTdPRWLeTALIQRERMVPTAMPNGVAFLHARHRAADKFPRQFLALARSKEGVSFGSPDERPTHLFFLLAFRRDqAHLRWLARLSWICRRRTTVSSLLQATSAEEISRQLAL-- ->tr|A0A1W9S0Y1|A0A1W9S0Y1_9BACT Uncharacterized protein OS=Candidatus Coatesbacteria bacterium 4484_99 GN=B6D57_02865 PE=4 SV=1 ----ISSKTIKIGLTGKTKDEILKEMVEVLSNSGNIKdPNRIyEAVVERERLCSTGFEHGVAIPHPRQGQPDIVENLTIAFGSSKNGVDFEALDEEPVYIFFMLAAPNDqEHLRALARLSRMLKKEEFREELNKAKTPDDVLKLISK-- ->tr|A0A1M6TWY0|A0A1M6TWY0_SELRU Transcriptional antiterminator OS=Selenomonas ruminantium GN=SAMN05216582_10985 PE=4 SV=1 ---------ENVPDKKALFRSLIQNAPQELQQQAPA---IITALCQREKLGDTCIAPGIALAHAQiPEIS--APYL--AATIIQEPVPWDQEGN-PVHIVImiLLPMiPAASSIHQLHDLMHKLADEELTDKLAAHPTPENLRQYLF--- ->tr|A0A0H0TJ97|A0A0H0TJ97_BRAHO PTS sugar transporter subunit IIA OS=Brachyspira hyodysenteriae GN=SZ53_00160 PE=4 SV=1 ------KERIFLENTSSSKEELFDFLSEKISELDPSydAENIKEGLYDREKDGNTVIADMVAMPHARMESIK---EIKVTIVSLLKPIEYSPDESiDLAYSIVAPIDANDEFIDVLTLIAMVVQDEELQNIIRNSKV------------ ->tr|B9Y3S9|B9Y3S9_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00459 PE= ------QEYIHLHCPAVTKAEVLQTASRWAAEAEIIadAALFLKGLWDREAEFSTGVGDGIAIPHCRLESIR---QPSVFFAHLENPVRWSPEEEvDLILVLAVPQSnAENTHIRLLSQLARKLVDEVFVSQLRELDQ------------ ->tr|A0A0C7L7M4|A0A0C7L7M4_KLEVA LicR protein OS=Klebsiella variicola GN=licR PE=4 SV=1 -----------IFEqSEHNKDSLIEFLARRLESTGKVDARYLPSVVEREAHASTLLADKIAIPHPM---GLVASTTQVTVAVFPQGIEWDAG--KVVKLVFMLAISEDAfvDSMIIYDYLTNILDDDIIDKLSSFDTFADFM------- ->tr|A0A0R1UZE3|A0A0R1UZE3_9LACO Uncharacterized protein OS=Lactobacillus satsumensis DSM 16230 = JCM 12392 GN=FD50_GL000512 PE=4 SV=1 ------SAELVEFnefKEPFSKLNFLKYATQILEKMHIADRQFLNELLERENMSTTAFPTGVVIPHSM---HMNALKTKILIVKFEKPVIWGGQR---IKFAFVVAQNTKDAqifNDFFQQLVEVLSDIYNVDMLYNSESSDELLNKI---- ->tr|X5NX75|X5NX75_ENTFL Transcription antiterminator, BglG family protein OS=Enterococcus faecalis CBRD01 GN=P746_01266 PE=4 SV=1 ------AKELYFSqidPADLTPEMLLDQMIQRMSIQKYCSSDFKKKCEKTRAAFSNKLSIRYRCPPCY--------------------------------------------------------------------------------- ->tr|A0A160NAA5|A0A160NAA5_ENTHR PTS fructose transporter subunit IIA OS=Enterococcus hirae GN=A6P53_11230 PE=4 SV=1 ------IEDLYFNqfdPTDQTPKMIREKLFDRLLVTGYVEEEFSQRMEKREAMSSTSFPSGIAVPHSL---EQQAKKSALSIMTLQETLKWDEYP---VQIVALVAISQDEAkefNDFFEMFIEIVSDPINVRLLAGAENFTEFILKM---- ->tr|R3WMX4|R3WMX4_9ENTE Uncharacterized protein OS=Enterococcus phoeniculicola ATCC BAA-412 GN=UC3_00114 PE=4 SV=1 ------RDNHFIVhYTGHTYEEALRAIADKLRKSQSVSDNYFDQLIERENASYTSFPSGIAIPHTL---AMDAKKTDVVILIPKESIPWGETN---VRLIVGLSISKKDRkifNKIFQRFVEVVSVKENVLMLSKQENPKQFLSRL---- ->tr|A0A173M3P3|A0A173M3P3_9LACT Putative licABCH operon regulator OS=Lactococcus garvieae GN=licR PE=4 SV=1 ------QENAFIHlKGEISKAAAFEKIGQWFFKNGFAEKEFAEKLFEREGLSSTSFSSGIALPHSI---RYEGRKTGILIFKPEKPLHWDNQI---VQLILSFTISPDDSkdfNKIFPHLIEILTEEYHVEYLRRSENRKEFLERM---- ->tr|C7HSJ3|C7HSJ3_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Anaerococcus vaginalis ATCC 51170 GN=ptsN PE=4 SV=1 -----TDKNTEFDIVVKDWEQAILETGKLLEESGYANENYKYNIINDVKNYGSYImiSPNVVIPHTRPE--NGALKIGCTIITIKNDIYFDDNNKDAIKVLIGFTAIDnKNHLEMLKNIINII-EKGLVDKLNYFLNLSKKDKLIY--- ->tr|R9LKM6|R9LKM6_9FIRM Uncharacterized protein OS=Firmicutes bacterium M10-2 GN=C815_02282 PE=4 SV=1 ----------HTTIKAQTVEEAIEKMCKPLIADHYVPEEYVQAVLERETFAPTSFYMGYALPHALNQE---AYKSAISVAWLEQPLRWGNYD---VFFILLLSIREEDrdLLRIfFDWWTQIVSDRMRYLKLMEKRTYPSFMRAL---- ->tr|B6FYB2|B6FYB2_9FIRM PRD domain protein OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_00864 PE=4 SV=1 ----------HVHETYESSDEIINKLCNELVEKDLADERYKEDVFRRESMSATSFSYGFAVPHSMEVS---TKESCLSVMVLDKPVKWGDFD---VRLIILLGIRDTDnsLLKIfFEWLSNTVTDSKKLARLLAVNNYEDFMKEV---- ->tr|A0A142KDF0|A0A142KDF0_9ACTN Uncharacterized protein OS=Propionibacterium acidipropionici GN=AXH35_00210 PE=4 SV=1 ------------NGAVTTREDAIRTLCNRFIAAHVAEADIEERVWERERISATSFPSGFAIPHPItMSG----NKSAIGVLRCGSSIDWGGQPVQLVAMFSVRPAERDLFGEIFEHFVRMLLSRPNVEALLsSADNFDAFM------- ->tr|W7CYC3|W7CYC3_9LIST Transcription antiterminator OS=Brochothrix campestris FSL F6-1037 GN=BCAMP_09175 PE=4 SV=1 ------------DVIKESKEDYIAFLGHELVDAKIITSSYYESVLEREKMSSTSFN-TVAMPHSLyRTA----KQSIFAVLYNKAPIIWDVHQVDLVLFMAISQDDSDRFNDFLQLIIEIASDPIAVRAIVEQTHYEGFM------- ->tr|A0A0M4GSV2|A0A0M4GSV2_9ACTO Uncharacterized protein OS=Actinomyces sp. oral taxon 414 GN=AM609_13030 PE=4 SV=1 ------------VEEELTQDEALERAFGLLRAAGAVGHSFLDDVRDRERRSPTAFGGRFAIPHSLyMDA----ERTALCVLVLAHPVPWGASAVDLVITLAVGPQERAVFRDVLDELVRVLSDPVGVDALVsAGIYYAGFM------- ->tr|A0A1T5K7I4|A0A1T5K7I4_9MICO Transcriptional antiterminator, BglG family OS=Okibacterium fritillariae GN=SAMN06309945_1969 PE=4 SV=1 ------------NLTVADSDTMIRTLGERMVEASVVDQGYVEGALQRERMSSTAFTEALAVPHAMtMTA----TRTAIAISVNETPLSWGEYRVNVVAFIAFSAVDRGSFQSVFDQFVEVFSNRADVQRIVrNAVDFPSFI------- ->tr|A0A221RZZ2|A0A221RZZ2_LACCU Uncharacterized protein OS=Lactobacillus curvatus GN=CGZ47_07610 PE=4 SV=1 -----QPELTIVTQERLTDQGAIELIGQRLIDQGYAKSTVVQAALAREALASTALG-RVVLPHADSQ---LITKPAIGLLIAPQSINWQHN--DKVQLVFFMALNETVHGQmrAiYHDLDQLIETPRLLKQVAQASDGTAALAILAQ-- ->tr|A0A1I3FJ93|A0A1I3FJ93_SELRU Transcriptional antiterminator OS=Selenomonas ruminantium GN=SAMN04487861_11548 PE=4 SV=1 ------EPCIRLDGEAGDWETAVTQAGNLLLAEGAVTEHYVRQMVRVVRNIGPYivVCDGVAMPHAHIE--DGARKVAVSFLRLKQPVFFSD-DKRPVDMLFAFSTTSeKAHLPLLSDLWRVFNSEHMLQALRTCPDAVTMRQQLQ--- ->tr|K1XDG6|K1XDG6_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_79C00364G0002 PE=4 SV=1 -----KSGGIYYRISGNDKKSVLMSVVENLKLPESVNREYlLEVLLAREELSSTGIGEGIAIPHVRNPIIFNIPKSLISLCFLEKPIDFGSIDDKPvHALFLMMCATPRIHLGLLSRLSYSLKDEKLKQAIINQASREEILTEFR--- ->tr|E8QXY6|E8QXY6_ISOPI PTS IIA-like nitrogen-regulatory protein PtsN OS=Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B) GN=Isop_0370 PE=4 SV= -----ECGGVYWDVPGSTPSEVLEAIVDRVPMRPDVPRDDlLALLRSREGVGSTSLGSGFAVPHPRYPLVHATVPPTLAVCHLAAPIAWDPNNPaDMvQTVFTLIAPTPRIHLRLLAKLMYALSDSAFRNVIARKASAEETITAAT--- ->tr|A0A1G0XXQ3|A0A1G0XXQ3_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_15470 PE=4 SV=1 -----RKGGIHYKVAGSTVEEILKNAVALINAPPGLDKETiVWHLLKREAMMTTALGSGIAIPHPRTPLISDISCESVSMCFLNGPVDFKALDNMPvSVLFIVLSANQPRHLQILSQISHLCRKDGFMELIKRQALREEIFDYAG--- ->tr|A0A1J5DFF8|A0A1J5DFF8_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_63_29 GN=AUK47_25160 PE=4 SV=1 -----RAGKVHRDVPSNGRESTIRAIVERTVLPASLAPAFvVAVMVARERTLWTAIGNGIAIPQVRQPIIAAGLPVTVSVSYLEQPLLFGAPDGKPiQVIFQIISPTIGEHLRVLAHLSRALLDPGFCAVIERRGSNEDLAMAAH--- ->tr|A0A1J4SVH6|A0A1J4SVH6_9BACT Uncharacterized protein OS=Elusimicrobia bacterium CG1_02_56_21 GN=AUJ51_03380 PE=4 SV=1 -----LEGNIHYGVPGGDKKAVMTAVADLLPLAKPGDKALaAQALWNREVKGSTVI-DGIAIPHTRSPLIFGSARPIATICFLKDKVFFDPGDKAPvRIVCTLVTPSIRAHLAILARVASTLHDKEFRALLDRAAPEEELLARLK--- ->tr|A0A1V5HIF2|A0A1V5HIF2_9BACT Nitrogen regulatory protein OS=Lentisphaerae bacterium ADurb.BinA184 GN=ptsN PE=4 SV=1 -----RADRFIMDMRARSASGALDELCALiSAKNLCLDTKDlRQRIDAREELLSTGVGHGIAIPHPRDPVPTLPEPVIIIVGISQKGIAFNSADGKPaHLFFLLCDQNIEMHLHMMGRLAKLLSNSETVDLLRGAKTPEEFLRVVM--- ->tr|A0A239A9Y4|A0A239A9Y4_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfovibrio mexicanus GN=SAMN04488503_1929 PE=4 SV=1 -----RAGGVMRGICANTLPELLCPVVGHmIPDAPEHQRELvLAMLLAREATGITAVGGGVLAPHVRAPLILGET-PRIVLVYPARPLPLSavpTPDNAPiEAVFVLASPTVRAHLTLLALLAAALRDADFRQAVLSRASEAALLTAAA--- ->tr|M7NM22|M7NM22_9MICC PTS system, fructose-specific enzyme II, BC component OS=Paeniglutamicibacter gangotriensis Lz1y GN=fruA_2 PE=4 SV=1 -------QMVALQMVTPTRDSTVAALAGLLQDAGRLSdlPGFLADVHRHEHQLATGLPGGIGLAHARSD---FVSAPSIAVGvmAYGQSLDFGATDGP-AHVVLLLATPassYSEHLMMLAALARSLAKDSFRESLRRANDAGVIAGLVG--- ->tr|A0A143WX38|A0A143WX38_9FIRM Putative licABCH operon regulator OS=Clostridiales bacterium CHKCI006 GN=licR PE=4 SV=1 -------EFFFEHLTGKTREEVIQEMCTKISSVHPLPETFYDLVMEREAVSPTEVGNGIAIPHPLHLVMD---ETFVAVGVLDKPIRWQKQQ---VKLVFMlcIQKDSDEALSVFnEVLSSLVLNRECVQKLEKEPCFHTLESYIHA-- ->tr|I3BR37|I3BR37_9GAMM Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Thiothrix nivea DSM 5205 GN=Thini_1212 PE=4 SV=1 ----LSPERVSCETEVSSKKRAFEQLAALLVTGyaGLEAETIFHALINREKLGSTAIGNGVAIPHACLPI-P---QPLGALLVLEDGIKMDAPDKKPVQLFLAILApanEAPNYSELITRLTGTLLQKSLIEQMCRYNDRQGMLDQFR--- ->tr|A0A1V3TS95|A0A1V3TS95_9PAST PTS sugar transporter subunit IIA OS=Pasteurellaceae bacterium 15-036681 GN=BMT54_05725 PE=4 SV=1 ----LPFENIHCDVDASSKKRVLELVGYYIAEyfnkneasqlnEnkGVCPIDCFSLLFKREKLGSTSINNGVALPHAKLAECECStiEKPVAVFLRLEKGVDYEAQDNRDVDLIYAVLFpeqSCERYKGALQKIAQQLNDKTLLKQLRAAEDSQAIWSILQ--- ->tr|G0GFU3|G0GFU3_SPITZ Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) GN=S ----LHPEYIKLKARISSFEEGVRLLLGLIRGLVdQDEKTLFSRVQEREAQAPTVLDHGLCVPHLRLDDFDDHV---IAVAVPERPFTYGGKEVDILILIISSKAQPSTYLNTLKGLATLFKDPDTREALLSAKHPEQFIRIIA--- ->tr|E0RRW0|E0RRW0_SPITD Uncharacterized protein OS=Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1) GN=STHERM_c07970 PE=4 SV=1 ----LHPEYIKLKARISSFEEGVKLLLGLIRGLVnQDEEALFSRVQEREAQAPTVLDHGLCVPHLRLDDFDDHV---IAIAVPERPFTYAGKEVRMLVLIISSKAQPSTYLNTLKGFGLLFKDPAIRESLLSAKTPEQFLRIVA--- ->tr|A0A098QSN8|A0A098QSN8_9SPIO Uncharacterized protein OS=Spirochaeta lutea GN=DC28_15415 PE=4 SV=1 ----LDDRLVLWKAKTTTLDSMVEHMLDKLYQyeDVsASRKQVTELLNARKALGGMVFETGLAIPHARIPGLRDLW---ILPGVPAEPFWENEVEVRLVVLFLVPAEVSEYYLPVLSYLTRLSRDNDVFSQWIGQPTRDAFIDYT---- ->tr|A0A1G3NWP7|A0A1G3NWP7_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_06855 PE=4 SV=1 ----LNEDYIVINGNLKNKEEIISFLIRQFERnyDFkIDSPKVINTIEERESLGGTVLPTGVWIPHGRLENFNDII---VSIYIPEEEFIQEGISVKMVVLFLIGKTTSNLYLKILSAFAQISSNESLFETILKSKDPRHFISNIE--- ->tr|A0A1G3LE82|A0A1G3LE82_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_59_5 GN=A2Y38_08375 PE=4 SV=1 ----IDPHLVLLDADVDSIDSAIEVGLKAIVElyPQeVMYDEVIQRLTERRLLGGTCFPTGISIPHARLPVFNDFI---IAAIVPHKPIISGEKcidtscadipPVRIVWLILISQTSSSIYLNTLAKLLEASKSESMMDALTSAESPSQFISIIE--- ->tr|A0A1V6K9K9|A0A1V6K9K9_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Candidatus Cloacimonetes bacterium ADurb.Bin003 GN= ----LEAHNILFENRVLTKEQVYKKLVDRLCSqyKLpVSGSKLLELILHREEEVSSAYPTGIAIPHIRMDGFNDTL---IAMAFLENPLDYNGIKVNWVVLILTDKTSSKTYLNIVAALLKLSKDKVAMKALASAGDGQSVIHYLK--- ->tr|A0A1W9VQA3|A0A1W9VQA3_9SPIO Uncharacterized protein OS=Spirochaetaceae bacterium 4572_7 GN=B6229_05490 PE=4 SV=1 ----IDSDFIITGKEFGSVVDAVNSLIELFDKkkILtASTDIVKTKTLDREKLGGTLLPPGIAMPHARVEGVDDLI---IGVWVPPKPLETDDGIVKILFFFLTSIAGSSLYLPMLSSIAKSCMDDKFFNKLISSNKDEv--HKLL---- ->tr|A0A1V6F6W9|A0A1V6F6W9_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Candidatus Cloacimonetes bacterium ADurb.Bin088 GN= ----LDARAIAFEQRVLPREQVYQEIIQRICAqrshNTpKCGQPMLDAILQREREAPMAYPSGIAIPHIRVEGLADTL---IGMTFLQNPLDYDGIKVNWVVLIFTDKSSSKIYLNIVAALLKLSRDEEAMKSLHGLHDGHDVIHWLK--- ->tr|A0A1V5V5J8|A0A1V5V5J8_9BACT CBS domain protein OS=Lentisphaerae bacterium ADurb.Bin242 GN=BWY31_01296 PE=4 SV=1 ----LNQNLIFFNVEGNDRETIYNHLISLMAKtvSLpCPPARVVSDIIAREDLINIVYEKGFAYPHIRYPQLMDLN---VVIGVLKKPVLLKQNdreETRIIVCSLVSPETSVIYLKVLAAFSRYFLlAPDAIAKLVNTGSPKAMIDFLQ--- ->tr|A0A1V5T9F4|A0A1V5T9F4_9SPIR PTS system fructose-specific EIIABC component OS=Spirochaetes bacterium ADurb.Bin269 GN=fruA_2 PE=4 SV=1 ---------------HSTRHDALVALADVLGTAPQIKnrQELSLEILKREELMSTAIGRGIAIPHVRLSsVTDLVVAVGLCKNDII---DFQTIDDVPVRLLFMIAAAYNQHayyLQTLSFFSTRLKNPALREGLLAARNPMEAYNLLIAK- ->tr|E2SP70|E2SP70_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_02962 PE=4 SV=1 ----LEQSSIVLDAsYGVNWMDAIWECAQPLLEQRCIEKNYITRMIELIHGYGPyiVISQRIAIAHAQPE--DGVLHLGISLHIYPKGLTIGNT--SIQFLFVLATPNQSDHLHILQDIMTLNEHEEYMNQIVQAENAKQVMYYLQD-- ->tr|H1BNH9|H1BNH9_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_01936 PE=4 SV=1 ----LKQQTIQILDEPMEWQQAIHKASEPLLHRAIIKKSYVQAMIDLLYDYGPyiVLANGVAIAHANPE--QGANALGLSLLINKQSITFEDDA-NVHFLFVLSNPDQDKHLHLLRDIMRLANDTALVDQLLKMDDTLAVLEGLKK-- ->tr|A0A1F9ZR07|A0A1F9ZR07_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_08395 PE=4 SV=1 ----ISLEKVRRVQRVADWQTGIALASSPLLVSNAVEQRYIDTMVANVEKFGPyiVIGPKIALAHALPQ--DGVNSLGFSLLLLDEPVSMMGR--DVSMLFVLAPIDKSSHFGIMKDLMKIISKEEHLRELENMKCEDVISFFEEI-- ->tr|A0A150KJX1|A0A150KJX1_BACCO Uncharacterized protein OS=Bacillus coagulans GN=B4099_0971 PE=4 SV=1 --LKLTEQNISILSYEISWEEVVDTIFAPLLERNAIEPCYLKAVKSAFykHYQTMLIGPDVYLPHARPDEG--VNYPDIQIVLFKKAVMFPN--HRPVSLMVALAPsADNSHVLTLSKLNDIFLDSKALRQIKSAASPKQLLKIFER-- ->tr|A0A090IT96|A0A090IT96_9BACI Uncharacterized protein OS=Bacillus thermoamylovorans GN=BT1A1_1055 PE=4 SV=1 --MTIDEKNIILIDNQIPWEDSVDITFSPIIKRGSVDQSYVQRCKQLFfeNYNKMLIGPNVYIPHAEPSNK--LKQPDIQIAVFFEPIYNPD--GSPFHVMVGLVPsNTNIHVPFLLRLNDFFIKKDSIKKLLASKNPREVLALLGS-- ->tr|R2T0U3|R2T0U3_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_02565 PE=4 SV=1 --FQLRIQQFSMIE-ADSWQEVFHFAFGKLLERGSVNERYVNRTLKLFekDYPFMMIAKDCYLPHTKPEDD--VTKPDYQVVLVKNRLQFAN--DRELKIMVALAPsKENKHVEWLLKINHALLQEENICQIEEISTIEDFYELLKS-- ->tr|A0A0M2SI08|A0A0M2SI08_9STAP Uncharacterized protein OS=Salinicoccus sediminis GN=WN59_09885 PE=4 SV=1 --GLLEEHQIKFVRDK-GIFQMAAKGLNLLKNRGSINQNYFDSTMDIFeeKYQTMIIGPNIYLPHAPVEEG--AIREDYQLLIN----------PSLEKCVLCISPeSNNAHVKKLLELNGLFTDDLFMKRLYKSN-EKDLVKLIEG-- ->tr|A0A1Q8E819|A0A1Q8E819_9STRE Uncharacterized protein OS=Streptococcus cuniculi GN=BU202_05540 PE=4 SV=1 --ILSSVSQVSIVE-EIEWRQIIHRSYEGIYSRGNVTKNYITKCQQSFyhSYTTQIISNEVLLPHSLPENG--VLEPDVQIILLKKTVIAPN--QQSYRMIIALAPgYENEHVSWLVELNKKLRISKKREEIFNAKTSQELFEKLK--- ->tr|A0A1U9K905|A0A1U9K905_9BACL Transcription antiterminator BglG OS=Novibacillus thermophilus GN=B0W44_12750 PE=4 SV=1 --DFITPDNITFKHSVSSWEEAIRLAAEPLIDSGKIEPKYVEAMVKHCdQDPYIVINPKVAIPHASPDEG--VHEVSMSLLKLDRGVHFAG--QYCIHVLVVIAAvDKHRHLKALMQLMKLAGSEEDVRHILQAASAEEIRSILKK-- ->tr|A0A1Y3PW00|A0A1Y3PW00_9BACI Uncharacterized protein OS=Caldibacillus debilis GN=BAA03_01135 PE=4 SV=1 --DLVPVEFIRLQQPARDWKEAILLASRPLLQNSIIEMSYIDSMIRVIqeYGTY-MIAPKVVIPHAKPEDG--AHKLCMSVLTLKNAVRFPK--NIFIQVLIVIAAvDRKSHIKALTQLYDLLMDKNNVETMIGTDNPMVIHRLFRE-- ->tr|A0A212JCK7|A0A212JCK7_9FIRM Putative Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=uncultured Clostridiales bacterium GN=KL86CLO ------MEFVFISDKADNWEDAIVKTSRALFDAGFVTEEFGSQCIKREREYPTGLGTQipIAIPHTD---SAFVHTSAICVLALESQVPFINMEDSESevpvEYVLNLAIKdGKNQVTILNKVLQVFNREGLPEQLER-KGNGYLKELIM--- ->tr|A0A242IXB0|A0A242IXB0_ENTFC Uncharacterized protein OS=Enterococcus faecium GN=A5852_000812 PE=4 SV=1 ------MKFKAIELNERSNIEVIKQCGLELLNEGLVGNSFIESCIEREHHFPTGLPVDppVAIPHTF---DLSVKESSVCYARLKKPVTFKQMDTQVDdlavEHVFCMALKdEHTYIEFLQKLILSIQSRNFIVQLSK-CEPEKLVDFLR--- ->tr|A0A0R1YHU8|A0A0R1YHU8_9LACO PTS system IIA OS=Lactobacillus hamsteri DSM 5661 = JCM 6256 GN=FC39_GL001041 PE=4 SV=1 -------DAVFV-SSESNQDELLKNIYDHLLESGYVKGNFLSHIIQREHDFPTGLSTKtlgsdlpnIAIPHTEG---EFVNTRLIVPVALENPIVFGNmikpnEKLEVKFLFMLLETNPDGQAQLLSQVMNFLAKTPesELKNLFSFTDPDAIYEFLTQ-- ->tr|Q97EZ7|Q97EZ7_CLOAB PTS system enzyme IIBC component (Galactitol/fructose specific) OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM -------DLIFI-EDAKDSNEIFKKIGQRLIQKGLVKDNFIDGIIEREKKYPTGMDLSviegqeynVAIPHTER---EYCLSKRIVFVKLKKEVEFKNmiapeDTLKVRYLFMIINNENDAQTNILANIMDFITNKENMDKLNKTDNEEEIFEFITD-- ->tr|A0A1W1ZCS5|A0A1W1ZCS5_9LACT PTS system IIA component, Gat family OS=Aerococcus suis GN=SAMN04487984_1272 PE=4 SV=1 -------KYCYI-TSKESSSEVFEEIGKILFEEGLVTEEFSEQIKIREKDFPTALDISpifsdvsgIAIPHTES---EYVKTQKVIPIKLNVPFKMRNmidpsSEVEVNFMFMILNNDSSGQSNILAKIMSGITSSDkkVLKEIADINNSNDVYKFAKK-- ->tr|W0FTS9|W0FTS9_9BACT Fused 2-O-a-mannosyl-D-glycerate specific PTS enzymes: IIA component/IIB component/IIC component (Fragment) OS=uncultured bacte --------------RFTSREEAIHALTQRLAALGKISstEQFLEEVYRRESLGPTALGEGFGCAAWQNcCGKRSGGLRVATLSEplQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDK- ->tr|G5IIL6|G5IIL6_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_03344 PE=4 SV=1 ------PSLIMTGATAENWEEAFRLAGNLLYREGYIEKGYISCMIQNVRNYGCYmmLCEDVALPHA--KAADGVIKTGFSFVTLKTPVILEHeQETHEIRLVVALAADNRmTHLTAMGELIELVCQDDKKEQLIQAEDAEMFIRLI---- ->tr|A0A1Q9YLB3|A0A1Q9YLB3_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=BO223_04145 PE=4 SV=1 -------DLIFLHQAFEDKETLLRFMTAWLEEKGYCSSGLYQSALRREQLTSTSIGSSIAFPHGDPEY---VNESHVVLMTLEKPMLWdGEEMADIIF-FAAFNMNSREEKRRIemfyKELIPCISDREFMTMLKTARDSVQLYKD----- ->tr|A0A0A2VZM4|A0A0A2VZM4_BEABA D-methionine-binding lipoprotein metQ OS=Beauveria bassiana D1-5 GN=BBAD15_g902 PE=4 SV=1 ----------------QDWRHAMQLAGDLLTKNGYTTNDYTKEMIHAVD----TLGPYIVVAPGIALAHsrpaPSVIKTGLSVTTLVEPINFGSEENDPVEIVFGLCATdSHSHIQIISRLVAFLDNEENIEFLKRCTNSSDVW------- ->tr|V5F357|V5F357_PHOLE PTS system, fructose-specific IIA component OS=Photobacterium leiognathi lrivu.4.1 GN=PLEI_3398 PE=4 SV=1 ---------IKINLNATSKEELFQELVNVLHTNNRISDkaQFLADIQQRESDSI-TCMDGIAYPHAKSKA---VLEPAIAVGIKKETIAYGDEDGVEPSLFFMIASPDngaDHHIYVLQELFGKFGDE-FLEAMHNATSEQQALDVL---- ->tr|A0A1S8T8J8|A0A1S8T8J8_9CLOT Putative licABCH operon regulator OS=Clostridium puniceum GN=licR_4 PE=4 SV=1 --------LFFYGLNMNSKEEVITFLSKELLRNGQVGTEFANSVFEREKISSTTFENGIAIPRPI-SNCF-CYKTIISVVILKKPILWDGQK---VKCIFLLSIREKDKKY-LIRffdLvVEHLSNKFNIEKIMEANTFDKFASII---- ->tr|C7XLV3|C7XLV3_9LACO Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus crispatus 125-2-CHN GN=HMPREF5045_02014 -------DLIDLSASVSDEQELFDLVGTRVIEKGFANLGYISGLEKRELSYPTGLkfpEIPMALPHVDPKY---IKKPFIYVIRNDKPIDVKqmgDSADmQSSNfLFLGLK-DGAKQPKLLAEIMAAFQNKQFVSAFQNADDKEAMYNLLT--- ->tr|A0A1T5L0G1|A0A1T5L0G1_9CLOT PTS system, galactitol-specific IIA component OS=Maledivibacter halophilus GN=SAMN02194393_02267 PE=4 SV=1 -------DLVFFDIETKSREELFLKIEEFLVEKKYAIKGLGQALIDREKEYPTGLalkGINIAIAHADPKY---SLDNKICAIKPQDKIVFQnieNLEKlNIDLiFILLLK-DSGNHLNILRTISSVFLDDDFIAAVKETKNSQELFQVLD--- ->tr|G7VXX9|G7VXX9_PAETH Transcriptional antiterminator OS=Paenibacillus terrae (strain HPL-003) GN=HPL003_01865 PE=4 SV=1 ----------IISnSQFTDKCEPIDYLCDLLLKNGCVKEDFYSKVVSRENSVSTGYD-GFAIPHA---ISLDAVSNEIAVLISPSGIKWDN---QNVYVVFMM-SVSPDTLvdfqELYAGLSLLLTETSVIGRLRKCKTFEQFKEIL---- ->tr|A0A139SLZ7|A0A139SLZ7_9BACT Uncharacterized protein OS=Cephaloticoccus primus GN=AXK11_06155 PE=4 SV=1 -----SPELLTLDLRATEHEAALREVAEPLRAHPDMRdyDRFFEQVIERERLDSTYLGNSVALPHARTSHvGRVVLAVG----RSAAGLRFENCES-PVHLLfvLGTPTSsPGDYLRVVSTLCKILASADNRAALLSASTPAAFLAAITT-- ->tr|B4D8Y6|B4D8Y6_9BACT Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Chthoniobacter flavus Ellin428 GN=CfE428DRAFT_5376 PE=4 SV=1 -----RPDHIALQTRAKDPKSAIDEVAGLLKSVPAVLdfQALLKGVQSSAPClPEPGGGFALCIPHTRGECvNEMVMSVG----RSEAGIVFPNVEL-PVRYVfcIAVPRAlAADYLRIVGLLARVFKDRTSEAELRAATTGTEFVDLLSR-- ->tr|A0A0C1RT36|A0A0C1RT36_9BACT PTS fructose transporter subunit IIA OS=Methylacidiphilum kamchatkense Kam1 GN=A946_09580 PE=4 SV=1 -----TQDRVLVNLSAKDKFEAITKVAKILEHSPLLQsfDAFLEAVLEAEKSGLTWFEQEVAFPHIRSQVvKELVIAAG----FFPSGVLFREAAP-LVRLIfvIGAPKKlNTNDIIVVGALARIVA--TNRQQLLKAKSAEEFVSLIAS-- ->tr|A0A1G3ZG03|A0A1G3ZG03_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium RIFCSPHIGHO2_12_FULL_41_10 GN=A3F67_10020 PE=4 SV=1 -----LLESINLSVKAKEGNTALKEVMKLLQYDPRVShwENFCQSILERPLFsLRANDQAAIMIAHGRTSSvRDLVMAAG----RNTQGITFHESEQ-PVLLLfiVGIPHElSTEYLRIMGSIARACGNPETLEKLLSTENSHDFMTTLSS-- ->tr|A0A0R2AFP4|A0A0R2AFP4_9LACO Uncharacterized protein OS=Lactobacillus vaccinostercus DSM 20634 GN=FC26_GL001418 PE=4 SV=1 ----LTTTNIVinDSPHAESWQYAIQHAFNNMLENHSISQSYVDKIIALTQQkgPYMYLGNGVFLAHAA--PQDGVKEIGLSLYISKIPIALTTSnhPQKNVNIIIGLAPIDqSSHLKVLSELFQNIQNKDWLEHLKSATTVTQVLEQIK--- ->tr|A0A0R2M295|A0A0R2M295_9LACO Uncharacterized protein OS=Lactobacillus paucivorans GN=IV54_GL000772 PE=4 SV=1 ----LTPDHIHVTSRILTWKQAIQRSFLPLLSGDYVDKSYVTEIIRKLEKngPFMIVKGGVLLAHSA--PSSKIHKLGMSLLELQHPVKMGDK---TITTIICLAPKReKQHLKALSDLLDILEDDDKYETLIHSERKSELVTLMA--- ->tr|A0A0R2BTL0|A0A0R2BTL0_9LACO Multidomain protein OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL001335 PE=4 SV=1 ----NATYTTDVIQQNTDWKNAIQISLKQLEYQNIITDEYINKIIELTESngDYMAIGKGVFLAHAA--PKAGVKHLGFSYTLFKKPFFIQNS-SKPINFVVGLAPVDqQKHLHILGNLLQFIQNEQLMDQLHKIKNYKELSMLLR--- ->tr|C9KLV3|C9KLV3_9FIRM PRD domain protein OS=Mitsuokella multacida DSM 20544 GN=MITSMUL_04187 PE=4 SV=1 ----SGEIPAAAKHAKPAWQNAIQYACQPLLQGHFIVQSYIDRIIALLARygDYMVLGKGVLLAHAK--TKDGVLASSAALTLFEKPITM-QS-GKEIRCIICLAPQNqNDHLDFLALLLQKLNDTEWCKTLFTRNSQQELESFIW--- ->tr|D3LAX1|D3LAX1_OENOE Uncharacterized protein OS=Oenococcus oeni AWRIB429 GN=AWRIB429_1501 PE=4 SV=1 ----FTKSNISFVDHANNFREALSLAFEPLIKNRSIETKYIDKIEYLTKKygPYMMIEKGVLLAHAK--PGDGVNKTDFSFLLLKKPVHLVNNnDSEAIKIIIGFATVDtSSHLEKLNDIMKILQNGKAMNNILSVSKKEQLLENSL--- ->tr|A0A0D0FFQ4|A0A0D0FFQ4_LACBR PTS system, IIA component OS=Lactobacillus brevis GN=N624_1572 PE=4 SV=1 ----ISEDHIQVLAGVSDWTVAVHQALRPLEIAGIVDPDYANHIIEATQTngPYMVLKEGIMLAHSK--PTDGVNELGMSVLVLKTPVVLSAHgQQRSLRVIFGLAPTDrQTHVQALSQLLALLQNEELYQRLILADNHDEVHHVLV--- ->tr|G7M425|G7M425_9CLOT PTS system transcriptional activator OS=Clostridium sp. DL-VIII GN=CDLVIII_4266 PE=4 SV=1 -------ELIQIRDDMLTKSDLIDEMCKLLISKGKVTEEYIISVYKRELMGGTLFDGTFGIPHGL---AEFVKKSSLAIFKLNNPILWDYD--CEVNVVIMLALK-EGDMKIVRSLFDTISMADIADGIKKAGSIKEISNLLL--- ->tr|R2T3Z8|R2T3Z8_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_01856 PE=4 SV=1 -------SLIFMDQDIQTKAAAIQFLADQLVAQGYVKPKFSETVFEREDMVPTCLETGAAIPHGYF--S-EVNVPQIAVLFPRKPIAWGNQL-A-AKVVLLLAFT-EDTSPVFSQIYSVISDKQAVEALTNLQSKEDVQACLD--- ->tr|U2TDZ2|U2TDZ2_9FIRM Sigma-54 interaction domain protein OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=HMPREF1985_01205 PE=4 SV=1 -------SNIVCGLGFSDKTQVMDRLAGLLQQHGAVEAGFLLSAYKRESTGATYLSGGIGIPHGD---AKYVKRPAIAMACLERPVLWENN--FMVDLVFLLALR-EDDQKYVNAFYRILSNKDTLSKLKAAKTPAECLTVMI--- ->tr|W6NIT1|W6NIT1_CLOTY NtrC family Transcriptional regulator, ATPase domain OS=Clostridium tyrobutyricum DIVETGP GN=CTDIVETGP_2012 PE=4 SV=1 -------NIVKLFYSIGSKEEIINIMARSMERKNYVRHEFYEDILDREDLGSSYIGNGVAIPHASY--ERNIIKPVIAVAVLKNPILWEEG--NKVDIVFILALN-GNSKKSFLKLFKTIKNTDLIESVKDMNDSKSVINKIF--- ->tr|I8RMK2|I8RMK2_9FIRM Sigma-54 factor interaction domain-containing protein OS=Pelosinus fermentans B4 GN=FB4_2527 PE=4 SV=1 -------ELIFYPNPEWSKPQVIDLLTQSLLSRDLVKPEFATDVVKRELIGVPILSLRVAIPHGED--PRYVNQTSVALAIFPEAIPWGEN--YRVNVVCLFAAA-TDGRELVQELGGKLTNDEIVDCLIEARTPAEAKRILV--- ->tr|E4RM19|E4RM19_HALHG PTS system transcriptional activator OS=Halanaerobium hydrogeniformans GN=Halsa_0651 PE=4 SV=1 -------NLIYLSPGFNSKKEAIEFLSKKMIVSGSAKDTYYNAVLEKENQGVTYVGNGIAIPHAES--K-HVNYSQFAIAILEEPIDWSGFE-V--DIICMFAFK-DLKTDHFKEFYNRLQKNiDYIKN----ADNIDLIKEVL--- ->tr|A0A0J1FJC5|A0A0J1FJC5_9FIRM Nitric oxide reductase transcription regulator NorR2 OS=Peptococcaceae bacterium CEB3 GN=norR2 PE=4 SV=1 -------DLLLPQVFSKNKENVLQSLADLMISHGYASAGYLESVMEREAFGLAVFSSRFAVPHASD--PTLVRRSGVALAVLKEPLSWGEGL-T-IDVVCMLALT-VSDAEIVYELSDLANRPERLEKLYTAKSREEMFQVLS--- ->tr|M1ZKA4|M1ZKA4_9FIRM PTS system transcriptional activator OS=[Clostridium] ultunense Esp GN=CULT_230015 PE=4 SV=1 -------DTIWPKAVFKTKMEVLDKICGKLYDRGYVNDDYKMKVYERELLGSTIYKNSIAIPHAT---TEETIKSTLGIVTLDNPVLWSED--YYANIVFFLVFK-ENCSEILSLLHSMANNKALLENILKANTSDDILHMIL--- ->tr|I8RDG9|I8RDG9_9FIRM Sigma-54 factor interaction domain-containing protein OS=Pelosinus fermentans B4 GN=FB4_1184 PE=4 SV=1 -------DFIMIDLACKTKQEVIETMSMVLFNNGFIKKGYIDSVFERENMSSTCFKKNVAIPHGLP--S-FVNETSIISAKLSQAIEWDDSK-NLVNLVFLLAVK-DDDINIINDLFRLLKQKNNIDEFLKAKNRFEFIKVLY--- ->tr|A0A0R1M9L7|A0A0R1M9L7_9LACO Transcriptional regulator OS=Lactobacillus capillatus DSM 19910 GN=FC81_GL000828 PE=4 SV=1 ---------------SVHaleqsetltEETSQKYLDQYFTF--inpnkitKILWDYCDFIQQHSDFIISNTFRVSLIMHLAG--A-------------LERYLTRSEV-E--------------VDQQKIvaiksdKLYASIKQAnELLDKTLNIKITEGETYYLV--- ->tr|A0A174I021|A0A174I021_9CLOT Transcription antiterminator OS=Clostridium paraputrificum GN=luxO_4 PE=4 SV=1 ---------------ESLiidvnrdmvLGAAADVTSKYLQC--ldvekvhPYLVDFISCIEHSNIFKLALNEIASTYVHVCC--M-------------IERILLCNNI-L--------------KSDENLeevkaklfTEFNFIKRAlRNIEVGFSIEIPDDEIYYLL--- ->tr|W7CSS1|W7CSS1_BROTH PTS system transcriptional activator OS=Brochothrix thermosphacta DSM 20171 = FSL F6-1036 GN=BTHER_00085 PE=4 SV=1 -------MV---------LQMSEESLNEFLTY--lnpskilPLLRAFIDDIELFEEINLTNGQKINMMVHIGC--A-------------LERCVLKETL-T----YYSK----PSPSQL--SKVVDYQTIaLLFSTSLQIKLPDSELFYLM--- ->tr|A0A139TGX4|A0A139TGX4_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Candidatus Stoquefichus sp. KLE1796 GN=HMPREF3037_0119 -------QCISILSGNYTkeevidnavAMMVEANCVDENYL--lsvykreAWLPT---YLQGGIGIpHGESQYVTKPVIHITK--L-------------DKPVCWDGEN-F-VDFVFTLALK-EDQTEAFEelykqmrePSFMQIlklcTSQeDILEKFMLIQY------------ ->tr|A0A174R4R0|A0A174R4R0_9CLOT Sigma-54 factor interaction domain-containing protein OS=Clostridium paraputrificum GN=qseF_2 PE=4 SV=1 -------DM---------CGKIIEAFKGEIKT--ydlastkDELIQFIYNVEEKFGLTLNLDTIVGAIMHMIS--S-------------IDRIKLGEHV-E----KYIA--I-DKL-SIDKEEISKIKEIlKPIEKKCDMEFVDDEIYYVY--- ->tr|C6PVA3|C6PVA3_9CLOT PTS system transcriptional activator OS=Clostridium carboxidivorans P7 GN=CcarbDRAFT_2720 PE=4 SV=1 --------F---------YNEIFQSLGNEIKE--lsmsdfkPLCINFLDNVRENITDNIDIYMVSGLILHLAC--A-------------IIRLINKEDT-P----KCIR--K-QKV-MSYSKEYNFLKESlRPIERFYNIKFSDDEFCHIL--- ->tr|U2N0F1|U2N0F1_9CLOT PTS system transcriptional activator OS=Clostridium intestinale URNW GN=CINTURNW_3780 PE=4 SV=1 -------LV---------QNQVFDAIKDDLEI--lyietykKYFNVFLENIRERLNIEFDLDMFVALTFHTTC--A-------------ISSIIKNNKR-K----VCKS--K-NDFKSKYQKEMDIIKEElSSIERVYSINIDEDEICFIL--- ->tr|A0A0U9HGA2|A0A0U9HGA2_9THEO Transcriptional regulator with an AAA-type ATPase domain and a DNA-binding domain OS=Tepidanaerobacter syntrophicus GN=TSYNT_91 ------------------IEQMKEVVKENTSIDSekyikdfiTF-----YKSLKKHNIILNEDMIVGFILHISC--A-------------IEKIQTGTFK-P----KINTAQI-SFLKEKYPEDFKTVASAlESMEKSFNISFPDEIYSNLV--- ->tr|A0A0U9HFI5|A0A0U9HFI5_9THEO Transcriptional regulatory protein LevR OS=Tepidanaerobacter syntrophicus GN=TSYNT_8113 PE=4 SV=1 -------------------KKIEQSLCEHLKA--vnaeecfRMSKSSVINISKALGLLIPSEVKIGIILHMAF--L-------------IEKLASGGKR-A----IFEN--L-QEYEKRHKKELVILENHlKPLEDYFNIDIGPHEYAYLC--- ->tr|R8PWL6|R8PWL6_BACCE Uncharacterized protein OS=Bacillus cereus VD136 GN=IIW_03909 PE=4 SV=1 -------------------------LGQQMQR--ddgalmiKTIRYALNTIQELISLQLNSDSLMGVILHMSC--M-------------IDRLQKGEKL-L------PYPDK-EARRQDEYWMYMKVKKAlQPIENTFDVQIPDDEVFYVM--- ->tr|A0A0K2M871|A0A0K2M871_CLOPA Transcriptional regulator OS=Clostridium pasteurianum NRRL B-598 GN=X276_02635 PE=4 SV=1 -------------------INLPKIIKENIYN--idgvelyKDVTLFLNILQEKLLIKLSDENMVGVILHLSF--V-------------IGRLRNEDNP-A----VYPQ--K-ENYLEENINLYNIIKENlNFITSKYKVEISDDEICYLM--- ->tr|T4I2J1|T4I2J1_CLODI PRD domain protein OS=Peptoclostridium difficile Y384 GN=QQG_1039 PE=4 SV=1 ----------------------VEGLKTSLKS--snynrifKDIKYVSDELFLVFNIEKKYDKVIGLMMHLAF--M-------------VDGLIGNTRE-I--------------EKLDKEktldyhKSLSKIKDIvSQLDKKYNIEINEKECYQIL--- ->tr|A0A1G4FHJ3|A0A1G4FHJ3_9FIRM Transcriptional regulatory protein ZraR OS=Sporanaerobacter sp. PP17-6a GN=zraR_1 PE=4 SV=1 -------DLIFVDKGFKSKEEILNKALCSMEQKGYVTSEYKWSVFERENLSPTLLNRYVAIPHGD---PTEVKRESIAVIKLQNSIEWCEN--IKINIIFLLAIN-DYGREKFKRLFKLVNDKRIFNRLQICKTKAEIKEVIV--- ->tr|A0A0K8JB96|A0A0K8JB96_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_0659 PE=4 SV=1 -------AKIIMAPAGKNKQELLRLLCDGIISEGYVNAGYYEAVLERENMGSYVIRQKVALPHAD---SSYVNHSVVVIAKTPEPIEWDEE--SSVSIICLLALD-INGKDGVRYLYNTFKNDNIVAQLEQAQSEQEIREVLL--- ->tr|A0A0K8JBZ5|A0A0K8JBZ5_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_0904 PE=4 SV=1 -------QNIYINLPYNNKKDVLTFLCNGLIQHKAVTAEYLLDVFQREEIFTTELDGGVAIPHAD---ESHVLASAISIATLKEPILWE-Y--KQVNIVVMLAVD-KHCFSALSSLLGFIVKADF-QKIVQLPSGRAIKEAIV--- ->tr|A0A0K8JBN2|A0A0K8JBN2_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_1075 PE=4 SV=1 -------RLIRIFHSLASKEEIIKIMTGVMCKERYVNEAFYNDVMEREAWATSYIGDGVVIPHTAT--TVNIIKPGIAIAVIKNKMDWDDAE-V--RIVFVLALK-TEHKDLFLRLYNVIKETDMVEKVCGLSDSKLMIAEVL--- ->tr|A0A1E6VFW4|A0A1E6VFW4_LISMN ArsR family transcriptional regulator OS=Listeria monocytogenes GN=AJN46_08495 PE=4 SV=1 -------------------EKLIASLEGNLQA--vssaeqlvYFLRKVISELQLQLNVILESGVDIGMILHLAF--L-------------IERVKLGAVD-R----EFPD--L-NEFAKNHMVEMQITQQMmENVEIEYDIVIPQSEIAYLT--- ->tr|G6B2D6|G6B2D6_CLODI Sigma-54 interaction domain protein OS=Clostridioides difficile 002-P50-2011 GN=HMPREF1122_00003 PE=4 SV=1 -------NL-SY------NSLIINFMTQNLEL--ldsvklfNYVNSSLFTIIELIDEDLKSKFKLGYILHCSF--M-------------IERCFKNTTF-PYNNIT--------ELI----sknhELYSLIREAfKPTEAYFNILIPDEEIAYII--- ->tr|A0A1E5GGU5|A0A1E5GGU5_9ENTE Transcription antiterminator BglG OS=Enterococcus ureasiticus GN=BCR21_06305 PE=4 SV=1 ---------------RTMkdqiakryvHGLSLKAIVNHITV--lnpqrlsIEVSQIYDDLCRQLNLSSDEKIMLRFLIHTCC--T-------------VERLVINNEY-S--------------TSDYNVsykdipNEASVIKMAfRPLEVSYNVQFSPLEIKYIY--- ->tr|A0A1B8RM12|A0A1B8RM12_9CLOT Uncharacterized protein OS=Clostridium paraputrificum GN=CP373A1_13885 PE=4 SV=1 ------------------deikndiiKFFSLQNILNQLTI--lnpdkivDEVDKIINNYEISLNKKFEGDLKLALFIHISM--L-------------IERLVLRENI-T--------------SHPDEEkfkqchsDFIELSEEIfRDVLKEYRVSLSLAEIVIIH--- ->tr|A0A1M6H7R5|A0A1M6H7R5_9CLOT Transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain OS=Geosporobacter subterraneus DSM 1795 -------ELMHLNVMAANKNEVLDRMANRMVENGYVTERYIFSIHEREIMAPTVFKNMVALPHGS---PEEIIQPAISIMTLSSPIIWDGN--QTVDCVFMLGLS-QYYKKEFRKFYSIINNEKVLEKIKKCKTVDMLMEVLL--- ->tr|A0A1M6IE13|A0A1M6IE13_9FIRM Transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain OS=Propionispora hippei DSM 15287 GN=SA -------ELVLVHPAVQGKEAVLQSLSDLLIGQQHVHENFLEGVYQREILRPTYMGNGAAMPHTD---PSFVKKPGLAIAKLATPIDWN-G--KPVQLVYMLALT-EECQTMIKELYSLICSQDFLSAVQQVKTPEQFIAAVH--- ->tr|A0A1M4U2H5|A0A1M4U2H5_9FIRM Transcriptional regulator containing an AAA-type ATPase domain and a DNA-binding domain OS=Alkalibacter saccharofermentans DSM -------EIIYMNKEIATKDEAIKFMCSDMLIKGYINESYLDGVLQRESMCPTFTENLLAIPHGY---CEDVIKPGVGIMIPKDPVDWGNG--RFVSIILLLALN-DEAKDEFQWIYKIITDREIVKKIKNQNSSRKIVEIFN--- ->tr|A0A1M5VLR4|A0A1M5VLR4_9FIRM Transcriptional regulatory protein LevR, contains PRD, AAA+ and EIIA domains OS=Sporanaerobacter acetigenes DSM 13106 GN=SAMN02 -------DE---------ENMYIEMLERVLVF--lnpiktyTIIKATFDYIVNKENIPIDDCLKVSYVVHCSC--M-------------IERIFLEESL-Y----YKEI----DILIEKEVELYNTIKKAmEIIEQSFSIYVPDTEIGYII--- ->tr|A0A1L5ZYF4|A0A1L5ZYF4_LISMN PTS sugar transporter subunit IIA OS=Listeria monocytogenes GN=BTR18_11270 PE=4 SV=1 -------IA---------KEIIEESLNEFLTY--lnpkktiEILSSFASVLEKKLGYKLDNTFKINLLIHVGC--A-------------LERMVLNDGL-I----YREP----KDMLET--NIFKALEQTnKEVIYKMNLKLTNDELCYLY--- ->tr|A0A1L8T298|A0A1L8T298_9ENTE Transcriptional antiterminator bglG:Sigma-54 factor OS=Enterococcus dispar GN=RV01_GL002586 PE=4 SV=1 ---------------TYPseaiqgekaVELINRFIHENFTF--ingdklaQPIWDFVTNLVEDVGLsTRDFGLEINLALHTAG--V-------------LERVLLKQPL-A--------------VTTTEAeqllneSLYEQVHNHiQSFGRMLRLNIPPSEEYYVL--- ->tr|A0A1L3SJ16|A0A1L3SJ16_BACIU PTS sugar transporter subunit IIA OS=Bacillus subtilis GN=BAX60_19000 PE=4 SV=1 -------AN---------iivRELCEDSLKKYLVF--lnphhiiEMLLEWLQTVQDELGAIFNNAVLIKVIMHTAF--A-------------FERVIKQNPI-AFSEE--------EEINDQMKEMVNVTERTlAPYEQKLGLRISDDEKLFIA--- ->tr|A0A1L8TNV4|A0A1L8TNV4_9ENTE Uncharacterized protein OS=Enterococcus hermanniensis GN=RV04_GL001706 PE=4 SV=1 -------------------PEMVDSLTNDFTP--eldvktlfLMIDDVLKLLRRDNELIIENTAIQALSIHIAF--L-------------VDKVKKEEER-P----LFDD--V-KYFHQENILFFNQVASKlSLIENQFSVRFTEDDIAYIV--- ->tr|A0A1M6GVS9|A0A1M6GVS9_9CLOT Sigma-54 dependent transcriptional regulator, gfr operon transcriptional activator OS=Clostridium amylolyticum GN=SAMN05444401_ ------------------dkinrevvKLFTLENVLNYLTI--lnpdkiiDQVEEAIYTLELGLGFRFQNDLRISLYIHISC--M-------------IERLVIKDPI-M--------------TYNKFQefeqchgHFIELVKKAfSVIEHFYKVEIPISEIGFIY--- ->tr|A0A1L8R2C2|A0A1L8R2C2_ENTAV Sigma-54 interaction domain protein OS=Enterococcus avium GN=RU95_GL004375 PE=4 SV=1 ------------------evvnnemiKNLSLNKIIDSLTI--ldsnkiiTQIEPCLDSLERYLNRQLNNSQKLNLYVHISC--M-------------IERLMRGKKM-D--------------SFPKDGyfgenqeQLGSLISTAfRPIEQLYNISLPIEECYYIY--- ->tr|A0A231VKZ5|A0A231VKZ5_THETR PTS sugar transporter subunit IIA OS=Thermoanaerobacterium thermosaccharolyticum GN=CE561_03490 PE=4 SV=1 -------AV---------RNLCRDSLNQFLTF--lnpdkiiNLLIRFCNRLEIELNKQFSNTMKIKLIIHTGC--A-------------LERTIINDSI-K----YKDS----VLNLNR--GIIEKVRNCsKIFSDALNINLIDDEIYLIA--- ->tr|A0A231VLX6|A0A231VLX6_THETR Transcriptional regulator OS=Thermoanaerobacterium thermosaccharolyticum GN=CE561_02695 PE=4 SV=1 -------------------VKMGNVLKENIDN--idgeelySDIQNTIMKLCDTLSICFDDDMLLGIILHFAF--M-------------VSRIKKGEKS-I----EYIG--K-DEYIKSNRSLYNAVKKAlTHLNTKYSIIIPDDEICYIM--- ->tr|A0A1Y4WSS4|A0A1Y4WSS4_BREBE Transcriptional regulator OS=Brevibacillus brevis GN=B5G50_26470 PE=4 SV=1 -------------------LKMQESLGEHLQM--vdgqdilADVRMCVGRMEERLNNYLVFDTRIGAYLHICC--L-------------VDRLKTGTQS-V----AYIQ--K-DSFLLENRKLYSLIRHElLPLEDKYEVVISEDDVCFIM--- ->tr|A0A242L8D0|A0A242L8D0_9ENTE Uncharacterized protein OS=Enterococcus sp. 6C8_DIV0013 GN=A5798_000768 PE=4 SV=1 ---------------------LSASLDGAIKS--vpslyellSETKKITEKIENDLSLVLEPGVDMGIILHLSF--L-------------VDNLLTDKHP-RLF-----------NELAEFKktyrYEMDIVKMNlIIIEKKYNIELPEDEVAYVT--- ->tr|A0A242AW76|A0A242AW76_9ENTE Uncharacterized protein OS=Enterococcus sp. 7F3_DIV0205 GN=A5821_001250 PE=4 SV=1 -------------------EGMRLNIATMLEY--kdgenliLSIREWVETMAAEINPAISYEIKIGLSCHIVC--M-------------IDRLKQGKNV-S----TFPQ--T-LTFKEKYSNEISIVQKNsQFLEAYYAISIPKDEIFYIT--- ->tr|A0A242LL83|A0A242LL83_9ENTE Sigma-54 factor interaction domain-containing protein OS=Enterococcus sp. 7D2_DIV0200 GN=A5884_000490 PE=4 SV=1 ---------------EA-qkmdesvaRKICMDYMEESFTF--inpkkiiNPLWEFADIIRTKLDLQLDYSFYVNLVMHLAG--M-------------LERVLQHDTL-S--------------LTQEELdqitsePSYDVVMKAaLYLKQLFQLELPMEEIYYII--- ->tr|A0A242B0Z3|A0A242B0Z3_ENTFC Uncharacterized protein OS=Enterococcus faecium GN=A5809_002284 PE=4 SV=1 ----------------GSshsftrnivFDMGIEAVDKYLYL--lagnkiqKSLMDFIEELECTFHKKFTYSILLKLLIHTAC--L-------------IERTLINGHE-L--------------KIISEDdtrpshEPIFHVKKAfKNIETEFGITVSYDECFFIY--- ->tr|R6RHI2|R6RHI2_9FIRM HTH domain-containing protein OS=Anaerostipes sp. CAG:276 GN=BN583_02313 PE=4 SV=1 -------EYCRFDAETDDWKEAIAMACEPLIKNGLVKPEYVEEMIHIvQNLGNYMvFIPEIAFVHGRK--D-NVRENCISLMKLKHPIDFGSKAKVDVKVIIVLGNITEN--ENLADLVRILAWENNMERIKHISSYEELLSLRS--- ->tr|B6FXG1|B6FXG1_9FIRM PRD domain protein OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_00560 PE=4 SV=1 -------SNAAFLYDADNWRDTIAEASKPLIKSGAIKEEYVDDMIKAiEDLGTYMvFIPEIAFVHASN--K-NVVNNAVSMLTLKNEIYFGDNSEVRIKSIVVLANKDEN--KNLIELINILTKNNNAEKFKNAEKYFDLKIMV---- ->tr|A0A1T5M7S6|A0A1T5M7S6_9CLOT Transcriptional antiterminator, BglG family OS=Maledivibacter halophilus GN=SAMN02194393_04059 PE=4 SV=1 -------DFVTLKYDCKNWREAIFAAADPLLKKGYIIEDYIRAMIEAvEKMGPYMvIIPGIALNHALA--EKGVLKDCLSLLTLKETIDFGDKDSESVKMIIVFGTNKSNkYFKILTDLIKVLEKKENIKKIYEAGNYEEIMDLSN--- ->tr|A0A1Y0L122|A0A1Y0L122_9MOLU Pentitol phosphotransferase enzyme II OS=Spiroplasma clarkii GN=SCLARK_001143 PE=4 SV=1 --------AVYLDNDSDDWIKNLKLGIKPLIADGVIDELWIEKLIQtTNKLGPYFvFSDLLAMPHISPDSSTK--KLATGFIYCKKPLKFFGNgYEKTCQIIVPLVTtDANSHMELLAQLVSLWNDQDFIKKL----------------- ->tr|G5F1I4|G5F1I4_9ACTN Uncharacterized protein OS=Olsenella sp. oral taxon 809 str. F0356 GN=HMPREF1008_00228 PE=4 SV=1 -----RPDLVSLGEDFATKDECLDAMLCQLETMELVQDGYRRSIFDREQMGATALESGVAIPHAAPE---EVRESSVSVMGLSQPLDWDGVS---VELVILVSLAEQdvDDfRDVITEVYKMTGTHELVHELASVPSAEEFASAFQ--- ->tr|F5YI41|F5YI41_TREPZ PTS system IIA component, fructose subfamily OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) GN=TREPR_0959 PE=4 --------GGFSPVPGSNPQELLTNLIRGLTLPRSVDaPTLLEAVLEREALMPTAIGHGIALPHPRNPLISVPGEQFVTIAYTGQDLDWNALDGkPVHTVILMVSASAKLHLHTLSRINFFCHQESFRELLTNRVSRDDFIRAIEE-- ->tr|F2NS67|F2NS67_TRES6 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Treponema succinifaciens (strain ATCC 33096 / DSM 2489 / 6091) GN=Tre --------EVLEDVPGNSCAKIFEYICDRIVVPSGLTaHQLQKELVEREKVLSTAVGNGIAIPHPRYPLVKNSSESKIVVAYLREPMDMQAPDVrKVYVMFVILSDSAQFHIKVLSALATLFKNEKFRKGIQACPSKGELLDLLRR-- ->tr|F4LLM4|F4LLM4_TREBD Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Treponema brennaborense (strain DSM 12168 / CIP 105900 / DD5/3) GN=Tr --------GVFYGVPGAAAADVYAFVCAHADFPAEISaDVFCRELISRDALMSTAVGNGIALPHPTHPLLKDASLQRIFLCFPERPLDMNAPDGrPVSSLFILLTGGSRCHLDILSQLANLFQKTSVRHLLERQADKNTLLAEMRK-- ->tr|A0A1V6EAE8|A0A1V6EAE8_9SPIR Nitrogen regulatory protein OS=Spirochaetes bacterium ADurb.Bin110 GN=ptsN PE=4 SV=1 --------ETWFIADPQNMSKVITALVFAAPIPSSINhKVLIDALLSREEMMSTAIGNGIAIPHVRLFDSTNLKEDIVVVAYLFEPVDWKAPDGkPVHTLFFVLAADETRHLQILAEIAQLASDEDFVDFLKTMPSREALIERIRQ-- ->tr|A0A061JD75|A0A061JD75_9CHLA Nitrogen regulatory IIA protein OS=Chlamydia suis MD56 GN=ptsN_1 PE=4 SV=1 --------------LVDSKEEALQYAARYIANKFELDAGVLFEMlMHRESLMSTGIGEGIALPHAK----DFLLNIGydIVVPVFLSqSVEYKALDGkPVDKLFFLFANQDRNHLNLV-------------NKIVHLGMSLEARLFLA--- ->tr|C6JQ41|C6JQ41_FUSVA CBS domain protein OS=Fusobacterium varium ATCC 27725 GN=FVAG_00122 PE=4 SV=1 ----LDPQFIFTDLKGKNPEEIITEMIERLSLKdkkiNELKDVIVKSVIKREKEISTGMGNGIAIPHARIENFNDFI---VSVAVLEEPIeveIAATHRTDKVKLVFliiSDVLKNKNILKVMSAVSKMaLKRKNLLEKIKEEKNPNKIVEYIQE-- ->tr|D1AJX9|D1AJX9_SEBTE Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0151 ----ISKELVFLNTESENVEELINNILDKAAEVdeevRNNLDKAKKAVLKREDETSTALGHGIVLPHGRIDGYDDTT---VISGTLKKPMkaiV--RNKEESIELFFiilSGLTKNRTVLKLMSLVSYLg-HQNEFLEKVKGVKSEDEFIELIQE-- ->tr|A0A0S8GCM9|A0A0S8GCM9_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SM23_46 GN=AMJ84_09655 PE=4 SV=1 ----LNEEHVLVAPPVESKEEATKQLLATFEPDldl-AARERAFKQLLEREKRITSYIDHGVAIPHAKVEGLTRVL---VGLVTSNEGFna--QDPPGATIHLLFlilTPHEKNTLMLQALAAVARLc-HTKEMRETLRRAKTPARIIKQIED-- ->tr|A0A1G0XDS0|A0A1G0XDS0_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_05830 PE=4 SV=1 ----LQREAIVTGINetGGDKRSIVAGMLDTLFANtglkdeGIEKSVLLDAIMFREEELTTAIGEGFAFPHARINETLKgSY---MLFGVSPGGVAFGSLDRKPVNFFLmsiVPGANSDMLLKSRAAFMRVm-NIPGIREKILSM-GTGEIWELLDK-- ->tr|A0A0S6VVJ8|A0A0S6VVJ8_9BACT Nitrogen regulatory IIA protein OS=Candidatus Moduliflexus flocculans GN=U14_00488 PE=4 SV=1 ----IDPKLIVVNMTATTKEEAFTALIDHAAHLdaefARQKPAIQTAIFEREQSISTAMGNGVAMPHARVEGYDNVI---VVAGVLKHSIeceLA-SKERGNVRLIFlivVGKTKNKLMLQLMAGITKLt-ENRQLFDAICREASPEKIAALIKD-- ->tr|A0A0R1VM53|A0A0R1VM53_9LACO Transcriptional regulator ManR OS=Lactobacillus ghanensis DSM 18630 GN=FC89_GL002373 PE=4 SV=1 ------GQNIFQGN-FKSYLDILNFlIGKANE-NGFIEKGFRESVLKREKLMSTYLSGKTALPHGNPSL---VKKSFLIALVLSKDTDWQGKMVNVVLL-LGIKSSDVSHSQKLMS------------------------------- ->tr|A0A1Y4W6X2|A0A1Y4W6X2_9LACO Uncharacterized protein OS=Lactobacillus gallinarum GN=B5E44_00580 PE=4 SV=1 ------KHHISFFK-DEKLPTIIDQlLDFNDWDSDEQKNCYLNTVNNRESLQSTYLGNGIAIPHGDPKM---ITNSCIAVAILNRPLNWGNNKTDIICL-LMIADQDKKTIEPFMS------------------------------- ->tr|A0A099HVR5|A0A099HVR5_9CLOT Uncharacterized protein OS=Clostridium sp. NCR GN=KD33_05970 PE=4 SV=1 ------NNNFYYKLQVKDKLELIELICNDMVKNDYITKVDKDSILKREALSSTEISNLVAVPHCISSENKNTI----AICTLKDAIKWGSASVKL--VFIAClnsEIKENK--HVFPFIHSSTKKSDIVNSLCECTSLNEFIEILM--- ->tr|B9Y3S8|B9Y3S8_9FIRM HTH domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00458 PE=4 SV=1 ------REELFFPaVEGKTKAEALDSLTASMVETGLISEAFATAIKEREAMSSTEITETVAIPHCFLSVPIDtML----AVGILKEPVMWGRSRVQL--LFIGIinpAVKKNK--CVFPMIYRLIQDPEKVQRLTRQTEADTFLRILF--- ->tr|A0A180CJR6|A0A180CJR6_LACRH Transcriptional antiterminator OS=Lactobacillus rhamnosus GN=PY66_05880 PE=4 SV=1 ------AHLIFWKDKMADKQAALDFLVSQLEATGKVEPEFRSSIFRRERLGSTELDSGTALPHAVP---TSVRSLGVAFLILQKPIHWNSVPVSIVVLACVPEAQVKIYRDLVMDIYRLVQTKQMVQMIVGLHSTDQFLELI---- ->tr|A0A1Y3VCU9|A0A1Y3VCU9_9FIRM Uncharacterized protein OS=Faecalitalea cylindroides GN=B5G15_08855 PE=4 SV=1 ------KELMFFKMKFDTKDQCLDFIIKKLESRNSVTAEFKQSVYQREKIGSPVLENGIAIPHGLP---TYVNEFTVVFVTLEKAIKWSDQYVDMVIMVVSPESETNAFEGLIMELYHISTNVEVLNGMKSIKNYEEYLSKI---- ->tr|K6Q7M8|K6Q7M8_LACCA BglG family transcriptional antiterminator / PTS system mannitol/fructose-specific IIA component OS=Lactobacillus casei 21/1 GN -------ELVQIIDTNMNWEKALRFSIKPLINEGIVTLHFEDVLVEQTkdQRSFAFFGTRMAIPHTVPE--NGALSEAFGFSIFKTPVSFPGNRS--ISIIVPISLRDtTKHLRAIHQLSHIAEDTSLIDKLINTNNSKTAYQLILE-- ->tr|A0A0F4LJA9|A0A0F4LJA9_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_09950 PE=4 SV=1 -------NYIVLnKDTNIEWKVALHKAIMPLLKDKKIEKRYEFELQRQInnPDNYSFLGTSISIPHSLPK--TGILGSGIGFLVSKTPIEMPYNKT--VNIIAPVAFSHtDNKLKAINQFTSLAMNKNIINKILSCKTSFEVYQIILK-- ->tr|E7MLV5|E7MLV5_9FIRM PRD domain protein OS=Solobacterium moorei F0204 GN=HMPREF9430_00518 PE=4 SV=1 -------DWVQITDKELDWKDAIRYAFEPMRKVNAINNQYIEKTMQSFdtQLSYSFFGTEAAIPHADEK--TLIYEEFIGFTVFQKPIQFPNGNL--VHVIAPIAILNtSKHIYAVKKLAEIVMNEENIDWIIGFTNESALYQAFIE-- ->tr|A0A1L8UNZ7|A0A1L8UNZ7_9ENTE Uncharacterized protein OS=Enterococcus malodoratus GN=RV07_GL003122 PE=4 SV=1 -------EGIILvSTKQLTWQNAMELSCQPLLKEQVINQNYQTILMSQMadEEAYYFLNNRIAIPHSSPE--NGVIKGGCSLLISVDPIIFPGNRP--IHFISPFAIGKkENYLLAINQLLQLSKDEEYQQEILLCTTEDEVRKKIKN-- ->tr|A0A241RQJ1|A0A241RQJ1_LACPE Transcriptional antiterminator OS=Lactobacillus pentosus GN=CEW82_10045 PE=4 SV=1 -------DRISVHRDVESWRQALNQAGILLQNDHKVSRKYIDTVMQVTasPKNYSFLGLETAIPHASPE--DGVLADGFSLVVVQNGVDFPGHPG--IKLIVMLAIKDtSKHLRAIKQLNELIMNQVTFNELLSCNDSNSLYKVIEN-- ->tr|A0A0T1XGX7|A0A0T1XGX7_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root482 GN=ASD31_22400 PE=4 SV=1 ----FLTMDISLSAIAPHKDAAIALAADRLAeTVDMAYGDARAALSGREALGSTALGKGVAMPHAVPWECPR---PALSLISLATPVEFDAPDHLRVDVVLALiwpRHRVGDFVRFSSLASRVVSDPAVLQAVRTSGAPGLIRSLLHA-- ->tr|S3I5A8|S3I5A8_9RHIZ PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN OS=Rhizobium grahamii CCGE 502 GN=RGCCGE502_29508 PE=4 SV=1 ----IIPEEIVINLPGGDRASALHHLATVLSrEVRVPTQTISSALLGRERMGSTAIGGGVAVPHALLTDIAE---PAKCLAILKHPIWFDAPDSEPVSVLLALlwpTSHENSYLPSLAGLMRRLRDPKLREALAAAQSVEEAALALSV-- ->tr|A0A1W6WBD5|A0A1W6WBD5_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium CPB6 GN=B6259_00850 PE=4 SV=1 ----LKPENIHFDVNPGhSKKSALKAISKLCGeHySTIKESALYKNFVGREKIESTGFGGGIAIPHAKIDNLTN---PFIAIVRFSKPVDWDSIDGKSVQVAIALvmpTVDTdNTHLEVLSHFSRKLADDEFLNRLLTEPDAVALYNYIIE-- ->tr|A0A246DPJ8|A0A246DPJ8_9RHIZ PTS lactose transporter subunit IIB OS=Rhizobium esperanzae GN=B5E41_23725 PE=4 SV=1 ----LPAENVSLDLVTKGKHSALSKIAAKIArRTALDPRMVLRAIWLRERLGSTAIGRGIAVPHAFVQPISS---PVTWFTRLAPPINFKSPDLDPVDLVFTIlwpRSKVHTFLPALSQLFRLVRVPLFREELRLARSPDEVIAILQG-- ->tr|F9NSB0|F9NSB0_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 OS=[Propionibacterium] namnetense SK182B-JCVI GN=HMPREF1162_0912 ----LSPDRFMAMPTGTGYWPATEALAAHLIDQGLADESFLATLRAREEEATMLLDGLVGFPHATIPgADRIILAMATIPR---------SPQQPGARVVFLMGVPDKTDyddtilVTVYDEIIRLTNDPDLLNRLSTLTNHEDVFWLMAS-- ->tr|A0A1R4GSU4|A0A1R4GSU4_CORGT Sorbitol operon transcription regulator OS=Corynebacterium glutamicum GN=FM102_14640 PE=4 SV=1 ----VSPEQFYVLPSLQSYEENLDAMLDNLVNRGLITADVQQGVKDREELRTTRLEGSVAFPHLSHPeIGDLVFAVGATKR---------EPEDSDVRLIFLLLLPEDVGgyddllVQLYDEIIRMAADQEQVKKVSSSTSFHDYLLHFLR-- ->tr|A0A1Y4AZ34|A0A1Y4AZ34_9FIRM Uncharacterized protein OS=Eubacterium sp. An3 GN=B5F87_09205 PE=4 SV=1 ----VEPEMLFLLPVDCTFREALDHMLDRLLEEGIIDEAFREAMLEREAKVTMLFDENIGFPHILYEGKKLIFALGVTGR---------DKAENGLKLVFFLGLPKNMDyddqilMKIYDEIISIAGNGQIMQGICECRSAKEFYSYMIK-- ->tr|E0RRQ9|E0RRQ9_SPITD Uncharacterized protein OS=Spirochaeta thermophila (strain ATCC 49972 / DSM 6192 / RI 19.B1) GN=STHERM_c22360 PE=4 SV=1 ----LKPEGIFLNMKAYKKKEElfkilVRRACEvGLVPGEMEEP-VLNELLAREAQSTTGIGEGIAIPHCKMEGLPHA---VIIAATIPEGMKYGSVDGKPVRLLFSFlfpADQGTQYLQVLAKLSRILKEEALRNRLILSSSPEEFRDILAQ-- ->tr|A0A166MZC7|A0A166MZC7_STAPS Putative transcriptional antiterminator, BglG family / PTS system, mannitol/fructose-specific IIA component OS=Staphylococcus p -------EFLGSIHQKMSRNEAIAEVMRPLEQAGMIHAQYKKEIINKlDEFGAYmVISPHIALLHGSTEFA--LKGVGMTLFHFEQGVYFGHERFDPVKVMIGLATDEPqKHLTALKELSDILMDDTMRVQLLNG-------------- ->tr|A0A0Q1AAI0|A0A0Q1AAI0_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_03095 PE=4 SV=1 -------EHLMFNMNFEHKQHLFEYLCKKAEQDGFITSweKMYKAVAEREQQGITELKSSVVLPHARGDF---ITRLFTYFVVNPQGISYQGIKGDKAKLVIFIgiPPQDKDYLKLLAAISRILSKPGFFDQLLRAEVIEDAVYTF---- ->tr|A0A1G3KIQ0|A0A1G3KIQ0_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_27_13 GN=A2Z98_02530 PE=4 SV=1 -------DLIFINPPVKTKEELFDFLAKKAFKKGLVENaeDFEYGLIDREAQGTTELKPGISIPHAKLDV---VKEPFIIICTFKKPIKFSPGFGRGVEVVFLIgsPKLDNTYINILASVARLMDKDDFIKEVKDANVSEDVIHSI---- ->tr|A4A2C5|A4A2C5_9PLAN Probable PTS system, fructose-specific IIABC component OS=Blastopirellula marina DSM 3645 GN=DSM3645_25694 PE=4 SV=1 ------PETIKTPLMGKSPRKIISELCELAAEAQLLwdPAKMSDAVLTRENMHTTALDNGVALLHPRRPLPDIISEGFLCLGRTYQGVPFGGSRGILTDVFFLIASVDdRSHLRTLARLSRVISDSAFYTKLRDAADPIATIEMIA--- ->tr|A0A1G0L1L0|A0A1G0L1L0_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium GWC2_71_9 GN=A2083_04400 PE=4 SV=1 ------EENALIAVPAGAVSDVVQALVSRVTFP-ERvdADLVVQRVVEREALCSTASPEGVALLHTARWEPRVLAaHDLLAVGRLSEPIDFGALDGGRTDMLFLILARNeRDQLVLLAKVARLCREPVFVDGLREASAAAEVVALVE--- ->tr|S4DKD4|S4DKD4_ENTFL PRD domain protein OS=Enterococcus faecalis 13-SD-W-01 GN=D920_00946 PE=4 SV=1 ----------HVHLKAETQKEVLEKMVRNAENKGLVTSSYLETVLVRENKGSTRIGKSIALPHGDMNE---IRHSFISIATLEKPVLWYTDE---VQMVILLGLKKQElgnpETKKFFSMIHYLiENQEVFQKVIKEKDKLNVLKLLS--- ->tr|A0A1I0GH96|A0A1I0GH96_9FIRM Lichenan operon transcriptional antiterminator OS=[Clostridium] sphenoides JCM 1415 GN=SAMN02745906_1190 PE=4 SV=1 ---------CFGYISAENRFQAIKELGAMLERKKGIGSQMINAIEKRERISSTEVGNLVAVPHVLMQGEFSS-CIAIGILDN--PVQWGSEMVQMVFLAC-FNQSGNQYARIFRTLYKVVHSEELVRRLIQADDFYTFQNIMCGR- ->tr|A0A1I5C7Z8|A0A1I5C7Z8_9CLOT Transcriptional antiterminator, BglG family OS=Proteiniclasticum ruminis GN=SAMN04488695_10610 PE=4 SV=1 ---------NFNIISASSKEEIINIMGLKLIKNGFTNERVIEEVLDREKMASTDIGNLVAIPHTLSSYQDKS-FISVGLLES--PVYWTKENVQLVFLVC-FNREDRENLDIFKYLYNFIKDEGAVKSMIRFSNFESFMKILKNV- ->tr|S0KTL2|S0KTL2_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_01378 PE=4 SV=1 ------PELVFLREQVENKEECLNFMIEKYQALGIAKEKFGESVWVREKLGDTSFSVSVAIPHADPS---EVNQTSIGIMTLAKKISWGINNV---NVILFFAISDTDIDvakSKITGLLEFIEKEENVEQLIQVTDKETLLELVMGE- ->tr|A0A1V5WNF5|A0A1V5WNF5_9SPIR Heat-responsive suppressor HrsA OS=Spirochaetes bacterium ADurb.Bin215 GN=hrsA PE=4 SV=1 ----------------------------------------LDGLLSREELSSTAIGHECAVPHIH---SDLVSETGIVIAVLDRSLDFGEELPvRIVCLLAGPVGETNQHLQLLSRVCQFLYDDEFRARMIACTTVDELRDLVQKR- ->tr|W1Q4X2|W1Q4X2_ABIDE PRD domain protein OS=Abiotrophia defectiva ATCC 49176 GN=GCWU000182_000569 PE=4 SV=1 ----LIKTPDQVQLTANNQDQALELVLAQASPQNLANPAFVQSVYEREQMGATSVYTGVALPHSDPK---TVTHSEIVLVSLAKPVSWGQN---QVKLIFLIAVAERDMKLfkeSLVALYALIEDQELMNQLSQCQDGASLKARLL--- ->tr|G5K9N0|G5K9N0_9STRE Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 OS=Streptococcus pseudoporcinus LQ 940-04 GN=STRPS_0774 PE=4 SV=1 ----LIGQRIYLHQDCQSLEECIAYLVEDKDTNCNYSSAYRESIMQRESLGSTSVYTGIALPHASPD---TVEVSQLSLLTLKNPIQWGAN---QVRVVMLIAIKGGEEEVykdALIHIYSKIDNQNFIRKLANAKTKDDFMCVLL--- ->tr|I9AR93|I9AR93_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Pelosinus fermentans B4 GN=FB4_1161 PE=4 SV=1 ---------------PLDWRLAVETVGRLLYQKGHIEKEYIHTMICNIEKYGPYiiVGKGVALAHAKPN--ETVLSEGLSLLVAPKGIKMDPDEKKTVYLLFAFCTQGGFDyIELFNQIASIGRNPALFSKCIQAKKTDDIYHLL---- ->tr|A0A1L4FSR9|A0A1L4FSR9_9MOLU PTS sugar transporter subunit IIA OS=Mycoplasma pullorum GN=BLA55_03355 PE=4 SV=1 --------------DKLDWVEVINKGVEILVENGYAKQTLADAILEStKQFGAYYvLERGLALLHAAP--GDYALKNGTSVMILDDFVRFNNQEDKEARIIVTLSAVDsSSHLNILQEFSHYFMNDEFKKEILQVKNIEEFWNLIDK-- ->tr|X8HNR5|X8HNR5_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 component OS=Olsenella uli MSTE5 GN=HMPREF1503_0782 PE=4 SV=1 ---------------ILDKVTAIEMLSGRLMELGIVSEAFPASVMAREEAASACFNGLFALPHATVMDAHRT---VVCTLISDAGVDWDGA---VIHLVMMIAVCDTDrsqFSVIFNDLARHLMDKESLYRLTDSTTAEEFRQMLC--- ->tr|A0A0G3EGT4|A0A0G3EGT4_9BACT EIIBCA-Man OS=Kiritimatiella glycovorans GN=manP PE=4 SV=1 -------------LGGGTPEEVLGQMCRCMEEQGFIENsdALLEQAMQREAISTTAMEHGIAFPHVrGVEGGGLTLAAGVH----RKGIHFDPDSRRLSRIFLFMTiptAASAFYLRLVSGLSESLSRKEVREEVLGAETPQELWKRL---- ->tr|A0A1G0ZRD6|A0A1G0ZRD6_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_20610 PE=4 SV=1 -------------IKAKSKEEVIEIIGHHSAKAGFVTDgaAFVKALIKRESLITTAVGSGIVFPHArDIKACGLTLAVGTV----KPGIKENGD---SLSIFFVSAvpmQTSIFYIELISKLANYFSKAENRKKILDCTKPEEMWKIM---- ->tr|A0A1B9JZ54|A0A1B9JZ54_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G12_08535 PE=4 SV=1 ----------------SQKSSIINLMATK--SEPYLSdvNKFFADVMTHEQEMETDVVPDIALPHAKS---SAVKTPFIAVAKNMNGVVWNN--SNKVKLIVLIGAPehaNKEHLTIIAKLASNLAMDEFVEDLLNS-------------- ->tr|A0A1F9AGS0|A0A1F9AGS0_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_61_14 GN=A2V67_17035 PE=4 SV=1 ---YLVPERVWIKVEVANRNDLLAYLARQTAGCALVPdeQEFFKLLIHREEEMSTGVGRGLAVPHADPP---AMKSTFLAAATLASPIDYQSFDRVSVDVVFMIFGCPddtSLHLRLLARISRIARLPGFLDRLRQVQTTPDFLRVVEEA- ->tr|A0A1M6NPT6|A0A1M6NPT6_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_02655 PE=4 SV=1 ---YMSPEQVYLDAPIRGKEEILHFVSQAFAQCGAAPdkRTVYDCMKEREDIMSTGIGGGVGIPHAACA---GVTRPAVVIARLARPVDFQALDAHPVDVIIAMVVPNarvSLHLRLLAAISRLVKSTNFLDDVRSASSSGDLFSHIKEI- ->tr|G8QTU4|G8QTU4_SPHPG Phosphotransferase system mannitol/fructose-specifc IIA component (Ntr-type) OS=Sphaerochaeta pleomorpha (strain ATCC BAA-1885 --DLLDKQCILLDMDCQDLQQILKSLLTTISEAHPQQapAPMMEKVLTNPGFSTVCMGFGCAISHARCT---EMKKTFIAVARLSPPLDLGADDKLPVALFFLLVGPQsspLFHIKILSRIARLLHASEFRKGLLQAKTSEDFHQLICNK- ->tr|A0A1G3RPQ5|A0A1G3RPQ5_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RIFOXYC1_FULL_54_7 GN=A3J97_06000 PE=4 SV=1 --SILDPACVVVDLDLRSKEEIIKALVDLLSAGGDVTnrDGLLHDVMAREALAPTGLGMSCAIPHAHSA---SVLCTAVAAARLKFPVDFGAPDGTPATLVFLMVGPKdaaGMHLKLLSKFARFLHDDAFRDAVMTTADASSFAELIYTR- ->tr|A0A1X2TGC1|A0A1X2TGC1_SALCE Phosphoenolpyruvate--protein phosphotransferase OS=Salmonella enterica subsp. arizonae serovar 50:r:z GN=R530_00730 PE=4 SV=1 ---LLALENIFVGEPLSNKEQVIQFLCGNLGVNGRTEhpFELEEDVWQREEIVTTAVGFGVAIPHTKS---QWIRHSSISIARLAQPVDWQSEMG-DVELVIMLTLGadeGINHVKVFSQLARKLVNKNFRQSLFAANDADSILALLEA-- ->tr|A0A1V3XFQ4|A0A1V3XFQ4_9SPHI Phosphoenolpyruvate--protein phosphotransferase OS=Pedobacter himalayensis GN=GY25_03695 PE=3 SV=1 ---LLALETIVVNEPLTSKEQVLQFLCGNLAIHGRTEnpLELEEDLWQREEIVTTAVGFGVAIPHTKS---QWIRHSSISIARLDKAIDWESDLG-DVELVIMLTLGaqeGINHVKVFSQLARKLVNKTFRESLFAATTPQSILDLLNA-- ->tr|A0A1S1XER9|A0A1S1XER9_9NEIS Phosphoenolpyruvate--protein phosphotransferase OS=Chromobacterium amazonense GN=BI343_00610 PE=3 SV=1 ---MLTAECLLPSVAWRSKAAALKGLVDRLWLLERCDdrYGMEEDLWLREQAYSTGLGHGFAIPHAKS---KHVLHPTLCLAKLEQPVDWGASDGQPVDMVLLIAFNasdaGAEHLKFFSRLARLVMHEDFRRQLREASDPQGLLTLLQS-- ->tr|A0A1Y6MFN4|A0A1Y6MFN4_9GAMM Phosphoenolpyruvate-protein phosphotransferase OS=Photobacterium sp. CECT 9192 GN=ptsI_2 PE=3 SV=1 ---ILVKQCVFKGADFANKEQVIQALVGNLGIQGRTDdaYKLEEDVWAREAVFSTGLGHGFAIPHTKS---DHIRHSSISIAHLDKPVDWMSDSG-EVDFVIMLTLNkdqGDQHMRIFAGLARKLIHESFRDSLRQAESPEAIIAIITE-- ->tr|A0A1T4LZ68|A0A1T4LZ68_9ENTE PTS system, galactitol-specific IIA component OS=Pilibacter termitis GN=SAMN02745116_00870 PE=4 SV=1 ---YIQPSLVFLGEEFEQSDNVFDYVHNQARKDGFVEEIFLEKIKAREVEFPTGIqleKIGVAIPHTDAE---CIREEFISVLTVPEGVSFARMDLPtsnvEAKIIFVLGLKePHAQLSMLQSLISILRQTEEIEKLQTQKEVQAFIEQIKEI- ->tr|A0A239W661|A0A239W661_LISWE Mannitol-specific phosphotransferase enzyme IIA component OS=Listeria welshimeri GN=mtlF PE=4 SV=1 ---FLKKGMVWVQSDIEKQEDLFQMVAESGKSEGYVTDDFLTRLTDREQTFPTGLkldGYGVALPHTDPE---CVTEQFIAVITVkDGGIPFKLMEDAgqtvEANLIFVLGLNePHSQLAVLQQLMGTIQDKDNVAALLRAKDEDEVKQILETI- ->tr|A0A157SD23|A0A157SD23_9BORD Nitrogen regulatory IIA protein OS=Bordetella ansorpii GN=ptsN_1 PE=4 SV=1 ---LLKDQDVLIDLDVPDKDALFDVASQGLANGCQISaQNILAALTRRERLGPTALGQEVAVPHASVE---GLDGIHVLYARLKQPCFFDGATGMPVMHALFLIVPMpanQTHLDMLAEVARLFSQPDFQKALRRAESPAGIRQAFQAY- ->tr|A0A0F9SWN9|A0A0F9SWN9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0402010 PE=4 SV=1 ---YLTPERVVVLKSVTKADALGELVDVLVATDGGVSaEELIKEVWKREDLMSTGIGNGLAIPHVRMS---GIRLAAMVVGVsRAGIDDYESLDKKPVHIIVLIAAPEgahETYIRMLAKVADVLKEDTLRQAAIEADEPATIHRILTEG- ->tr|A0A161QJF2|A0A161QJF2_9BACT Uncharacterized protein OS=candidate division Hyd24-12 bacterium Dam_1 GN=AO394_04560 PE=4 SV=1 ---MNKSCYCVWNLQS-tDRESALSELLSSVPGIGS-HsrEMLLKALQIREQAGATLVTTGIAMPHCRS---ILVDDMVIAIGKSDSG-iPWPEEPAR-VVVMFISPVKlsgPQEHMNLIAHLANQMKTN-GPEKITGADSPERLAGLLGL-- ->tr|A0A1V6FFL8|A0A1V6FFL8_9BACT PTS system fructose-specific EIIABC component OS=Lentisphaerae bacterium ADurb.Bin082 GN=fruA_3 PE=4 SV=1 ---LLPKEHVLFGLPLNiSRRELLRMLSEPLAKDGAIDdiEVFLDAVERREAEMSTQMNGGTVFPHASS---ATVQCLAITVGMAPEPGfPFDPDADEKGRVFFLIAIPaaaPAAHLPLLTHLAGFITAKGKLEKLLQADSAAAVHKMLLA-- ->tr|A0A1V5KRA7|A0A1V5KRA7_9BACT Heat-responsive suppressor HrsA OS=Verrucomicrobia bacterium ADurb.Bin474 GN=hrsA PE=4 SV=1 ----MRPDHVLCPLIA-sNAQDAIQILMDGMKGLPAIThsEDFLKEVFLREKESSTHIGHGVAIPHARS---RNVSGMVLAAGRLDQEIl-WDS-SGKPVRIVLLMGIPpqsIETYLSVMKAFAHGFRKQNLASRILQAPDTNALSQILSS-- ->tr|B0VG30|B0VG30_CLOAI Uncharacterized protein OS=Cloacimonas acidaminovorans (strain Evry) GN=CLOAM0343 PE=4 SV=1 ---YMRPENIFLDFTAENKYDAIRILSEKAKELKLVRDarWLYEVVVAREELVSTAIGNGVALLHPRHLHPSKIKAPSILFGRSSEPVDFDAPDNKPVNIFFMLLLHNdKQHLFSLSYISRLVMNQDILKGLTEAKDAQEIHQLLTV-- ->tr|A0A1V6DHB9|A0A1V6DHB9_9BACT Nitrogen regulatory protein OS=Candidatus Cloacimonetes bacterium ADurb.Bin117 GN=ptsN PE=4 SV=1 ---YMRPENIFLDFEAENKFDAIRILSVKAKELKLVRDarWLYEVVVAREELISTAIGHGVALLHPRHLHPSKIKTPSILFGRSSIPVDFDAPDNKPVNIFFMLLLHNdKQHLFSLSYISKLIMNPEILAAFSTASSVEEIHNCLTV-- ->tr|A0FL35|A0FL35_LACPA Putative PTS fructose-specific IIBC component (Fragment) OS=Lactobacillus paracasei PE=4 SV=1 ----IDIKNIDTSIEPMTKDQAIARMINKLKLNGYVQdaDTFSKAIYQRENEISTAVGYGVAIPHART---SAVKKSTISVFRDLSGIPWGQE---KVNLVFMIAAEedaSDEHLKMLSKISTFLMDESFRAKLITAADPNEMYEILVQE- ->tr|A0A0R2XK30|A0A0R2XK30_9BACT Uncharacterized protein OS=Verrucomicrobia subdivision 6 bacterium BACL9 MAG-120924-bin69 GN=ABS33_00960 PE=4 SV=1 --DLINEKNLIPNLVAKDRSLAYSSMLQVLLNNGFIKEdittSCLEGLKAREAKMTTAMGGGFALPHATIP---KLAKPCYLLARCPEGVECEAVDGKLVTLFFLILTPPdhsQEHLQTLATVAKFFNRRGIKSKILQAAGIPEILSIIRP-- ->tr|A0A1T4WNZ9|A0A1T4WNZ9_9FIRM Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Gemmiger formicilis GN=SAMN02745178_00883 PE=4 SV --ELMNPKGVLLYAKIDNSADALGILVELQEGIGVITNgnAYYNAVSYrETFGGTTAIGGGIALPHACNA---GVSAPGISALLLRRGVDWGAPDGEPVDLVFMIAVPPgseSLHLQILARLVNLLSRSDLVESLRTASNPHRFVELIAK-- ->tr|A0A0S7WK56|A0A0S7WK56_9BACT Uncharacterized protein OS=candidate division TA06 bacterium DG_26 GN=AMJ40_02565 PE=4 SV=1 ---LLSPETIAFPLHASRKESIIEELVGLAVAGGAIShkKEVVQRVKEREEILSTTVGKGVFIPRVRSR---HVSRICLCLGITRKALDLGALDGNHVRLCVFLGIPEgkiEAQVKYLVRIFRLFNQDSFRSALLKAADKKDVIEIVRSE- ->tr|H6SR97|H6SR97_PARPM PTS IIA-like nitrogen-regulatory protein PtsN OS=Pararhodospirillum photometricum DSM 122 GN=RSPPHO_03193 PE=4 SV=1 ---LITPDSILPALRVSSKKQALQELAKRAAELtEQHERAIFDVLLERERLGTTGVGNGIAIPHGKLPT---LTGLHGLFARLVEPIDFDSIDDQPVDLIFLLLAPEsagADHLKALARVSRLLRDRATCEKLRGANSAEALYTLLSQ-- ->tr|A0A0R1SY26|A0A0R1SY26_9LACO PTS system fructose-like transporter subunit EIIC OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL001656 PE=4 SV=1 ---KNIAIKTVFDIAALSKKEVLTEVTTSLFNDGIISdqAGFLHDLCYRENELSTYIGHSIGLPHTRS---KYVKRPVILVGRLSHNISWDQDHS--VNFLVLIAVpEtatGSLHLRILAHLSGLLIHDDFREKFVNASPVEAHKMLT---- ->tr|A0A0M4JIP4|A0A0M4JIP4_9MOLU PTS system, fructose-specific IIB component OS=Spiroplasma cantharicola GN=fruA PE=4 SV=1 ---IYKEKNIFLNIDLNSKDEVLKYICNKANELGIYQdtKSLLKAFYDREKQGTTGFEDGFAIPHAKV---KGITSASIICIRTLNGIEWEALDGQPSNVIIALIIPEnasKEHLDILSQTAKKLMDDKLRQKLKDAKDSKEFSKLIQVK- ->tr|A0A0K1P740|A0A0K1P740_9MOLU PTS system fructose-specific IIABC component OS=Spiroplasma turonicum GN=fruA1 PE=4 SV=1 ---SEKNLLVFINKDFSSKEDILKFISEKSSEANFIKdaDYVYKKFIERENLSSTGLQDGFAIPHIVV---EGLIEPYIICIKNNRGVFWDSLDGKNTSFIISIILPKndkSEEKDIISEITKKLYNKSFKEAIKKSQLTSQIEELLFLK- ->tr|A0A222EPW9|A0A222EPW9_9MOLU PTS system, fructose-specific IIB component OS=Spiroplasma corruscae GN=fruA PE=4 SV=1 ---NKENVLIYVNKDFKSIENLFIFISQKLYTSVGLKerNDYIN-FKSVYDDSIIAySKDNFILKKCAI---PEIKDTFIICVKNNRLIKTDKFEKTK-NFFIFVLHPIkenFISNIIFDELLKKLKNKEFRDIIKTIGLTFEIENLLISK- ->tr|A0A1T4JFQ6|A0A1T4JFQ6_ENTFC Probable PTS system regulatory protein OS=Enterococcus faecium GN=FM130_11815 PE=4 SV=1 ---LISSNVYF--DHLDSKEAAIRFLVdQQQFENEDLKQRFLHSIFEREEIQSTYLENGFAIPHGNPN---VVKQTSVAVLIADKPFSWGYQ---KADIVVLLMIREEdvkEVEPVMKMVMQGIEDKNWfISKMLEVRE------------ ->tr|A0A233IRT6|A0A233IRT6_9FIRM Uncharacterized protein OS=Paraclostridium benzoelyticum GN=AVM15_11755 PE=4 SV=1 ---IFSQDLFFIDLDFDNKYDVISYMSDKLLENNYIDEEMKNSYIEREKIATTEIGNMVAIPHGAHG---KVFKNAIAIGILKSSMNWEVG---QVRLVVMLSLQKEsilNYEDLFSNIYKRIDSIAKvISIC-ESKRYEKFISMFK--- ->tr|A0A1V6AQC1|A0A1V6AQC1_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Aminicenantes bacterium ADurb.Bin147 GN=fruA_4 PE=4 SV=1 ---YFKINQLVFELRASEKVAAVEELIDVLAKQKLVRnrKMILTRLMDRETLESTALGDGIAVPHARVDS---DGEIVIAVGRSSEGIDFSAPDKKKVHLIILIIWNPtlpGLFNHLFAGLAHFLRDPHFRRRIFEAKDKNALWEALGEI- ->tr|C6JPX1|C6JPX1_FUSVA Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Fusobacterium varium ATCC 27725 GN=FVAG_01021 PE=4 SV= -----EKKYIFRLNEKLTRDEVLETVGNKFYHDGIVTTGFVKAIQQREKDFPTGMilekGTNIAISHTDD---KYVIKDRIAIIIADNPVIFKSIENGkndiKCNIFFVMALTKeNKN-EILSAMADLFENYEDILKKFPLMTDEEILDIL---- ->tr|A0A0R2LJR0|A0A0R2LJR0_9LACO PTS system fructose-specific transporter subunit IIABC OS=Lactobacillus kimchiensis GN=IV57_GL001790 PE=4 SV=1 ---VLDPKDIVLDVKAASKNELLKYLANLVSNSntTVNTEEIYGKYLVREKNCPTDLGSGIALPHVQV---ESITKLTMLVVKLQRSIKWSKSE--SVDIVISFLVPEtdknYQYIPYLASVARLLLRPSFVQSLRQTKNKFAIVKLF---- ->tr|A0A0R1K3Y5|A0A0R1K3Y5_9LACO Uncharacterized protein OS=Lactobacillus alimentarius DSM 20249 GN=FC67_GL001714 PE=4 SV=1 ---ILDVKNIVMEVDLHSQAEVLKYLTDFYHRLnlATDSEKLYGRFLLREKESATNLGSGIVMPHAVD---SSVQKLTMIILKLENPLMWDDQ---KVSWVIALLIPEsekdFSHVKYMAGIARLLLKPTFVYALKETTTAKQVEKLF---- ->tr|A0A1A0EA54|A0A1A0EA54_RAOPL Uncharacterized protein OS=Raoultella planticola GN=AYO04_16555 PE=3 SV=1 ---LIVPEMIQWELDVTDKNEVIKKMVDNLWLHrrTDARDKLYQDIWARENPFPTVVGSGFAIPHART---SAVHVSTISVARLVNPVTWGGV---QVDTVFMLSISesgaENDHMRYFSTLARILMNDEFVSKAKATTTPDELYNLIFS-- ->tr|D7VFB9|D7VFB9_LACPN Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus plantarum subsp. plantarum ATCC 14917 = ---LINKNTIQFaTASHLDWQQAIALATLPLLSSGNVEQSYIDAMIRNVYSNGPYinIGDRIAFAHARPE--EGVNKLGMALLCLDEPIELLDNQ-HRIQLIFVLAASNdRSHLKALAELASMLGDKNRLKQLLDARKVSEVESVIAEG- ->tr|A0A1Q2D4H8|A0A1Q2D4H8_9ENTE Uncharacterized protein OS=Vagococcus penaei GN=BW732_02875 PE=4 SV=1 ----VNQDHVFLKQNLKTKEEVFKFLATTFSQKELSYSDISSELNKRELLGYTSLNTGIAIPHVPP---YLVKVSTVMFITLKKPISWGYNK---VSLILFLAIKEEdvfYAKNIIEEIQEVIESSKQIETISASSSFEEFKKKLLR-- ->tr|A0A1V4DG94|A0A1V4DG94_9ENTE Uncharacterized protein OS=Vagococcus sp. D7T301 GN=BW731_04670 PE=4 SV=1 ----SDNQYVYLRKNFDNKEEILTFLSNELENADKVTNSFRETLFQREINGSTEMDIGVAFPHADP---RTVKETKIVFLTLAKPIKWNMLD---IQIVCLVLISEDdmgQAKNIIATLYDLFKNQKKLNQLIESKCKKEFKDCLTK-- ->tr|A0A0L8EWQ4|A0A0L8EWQ4_9CLOT Uncharacterized protein OS=Clostridium sp. DMHC 10 GN=AGR56_17770 PE=4 SV=1 --DIFDEKLCFLNSEFTDFKEAIYHYGSIMEEMGYAKKGFCKSILEREEKGSTYVGKGIAIPHGES---VYVNQSKVCIVKFKEPISWEDND---LEFIIILCLNfeNiSTTKNFFKNFYTVLESDKTMLDIKNAKSAEEIINAFK--- ->tr|C4V3X4|C4V3X4_9FIRM Putative licABCH operon regulator OS=Selenomonas flueggei ATCC 43531 GN=HMPREF0908_1218 PE=4 SV=1 ----FRPEGFYVDQLFHTRDECLNFLTDEAVRNGWMDAEGKSSVFEREHMSSTAIGDFVAIPHALL---TEHMISNISVLILKEPVQWEDF---PVRVVFLLNIEQSkasLWEKMFLKLYSFIKEYHGLESLLKHKSYEQFMEDFIA-- ->tr|A0A174B9F1|A0A174B9F1_9CLOT Putative licABCH operon regulator OS=Clostridium disporicum GN=licR3 PE=4 SV=1 ----FKESLFFNHLDVDTRDEALENITSKLIDEGYITQCVKENIFKREDLASTEIGELVAIPHDMN---EEIKQSFISVSVFNKAITWDKE---KVQVVFFIGMSTVdkeEWKSYLEQIYKNIIDGEIIRKIIKCQNFEELKMLVSK-- ->tr|A0A1G4A1A1|A0A1G4A1A1_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium GWF2_62_7 GN=A2107_14510 PE=4 SV=1 ---MTQPAFIAPGLTAKSKASIIRDMVALAVSTGRVYdpHALIASVEEREALCPTAFPGGLALLHSRYQQPAFSEEPFIVLGRALQPIHFGSPDGRPTDLFFLVCCQDvKLHLHTLARICLMAQKSALLALLREADDATSMYDCLVN-- ->tr|A0A1G0YFS1|A0A1G0YFS1_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_57_35 GN=A2X46_16800 PE=4 SV=1 ---LFKPELIAPAMTSRTKASVLRDMVKLAESSGLVNypQELVRSIEERERMCSTALAGGMAILHPRNHEPYMFGDSFVALGKSIQPVPFGSPDGATTDVLFLVCCQDdRIHLHVLARVCMMCQQTSLLLELREAQDAAQMYDLLVK-- ->tr|A0A1V6FEH3|A0A1V6FEH3_9BACT Nitrogen regulatory protein OS=Lentisphaerae bacterium ADurb.Bin082 GN=ptsN PE=4 SV=1 ---LCRQEFMHPSLPGQSRSAILKALTELAETTGLLYdpKDLYERLRQREEEYSTAMSGGIAMPHPLVRDDFLFETPFVCIAKTPRPVFFGQaDDGQGTDLFFLICCLEsQQHLQTLGRVSLLCSRTSLPDDLRAAETSAEMYEALQN-- ->tr|F9QEM2|F9QEM2_9MOLU PTS system protein, fructose-specific family, iiabc component OS=Mycoplasma anatis 1340 GN=GIG_00491 PE=4 SV=1 ---LLNPKSIFINIDVNDHNDALEMIAKKLYEANFIEdkTRFLNALNYRENLMSTALNDGIAIPHGIS---STVIQPTISLAILKNGIDWKAEDNKKVNLIFTIVLSKedrEIQLDSIQVIADYSLDDNFHSEIMNAKTQEQAYEILVK-- ->tr|C4XF07|C4XF07_MYCFP Uncharacterized protein OS=Mycoplasma fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18) GN=MBIO_0464 PE=4 SV=1 ---FLNKNSIFVHSNFDKKDDVLHFLSHQLNEQNFVSdeKKIYEAFLYREELMNTAIGGGIAICQALS---STVKKDTLCILTMNndGVNDWKADDEKNVNLVFALVLSKnnrNLQIDTLQMISILALDNTLDNKIMKAKNADEIYEVMSK-- ->tr|C0CZN4|C0CZN4_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (Fragment) OS=[Clostridium asparagiforme] DSM 15981 GN=CLOSTASPAR_02461 PE=4 SV=1 ---LLDEDLIVLDYQGRDKDQVLRFMAEGLEQKGYVTEQFLEDVMARESRGSTALGFGVAIPHGVS---GYVNRPAVSVVRLEESMDWAG---EPVSLIFMLALNfkDiESTRAFFNGFYHLTCEVKIVELLRGVTSPGELIRVISEN- ->tr|R5EG99|R5EG99_9GAMM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Succinatimonas sp. CAG:777 GN=BN779_00465 PE=4 SV=1 ---AIDEHCVIYKLKANTLDEVIQVLTDRLFEVKAIKskHDLLKGINEKIAKNPAGIAHGIAIPHTRG---NYVNRSSLAVATLKTPLNCGASDNKPCDLFFLIAVPDdgVSHINLLSNLSLMLSEPGFADKLRHSGSNEEITKRL---- ->tr|A0A1C6E1H8|A0A1C6E1H8_9FIRM Probable licABCH operon regulator OS=uncultured Eubacterium sp. GN=licR_6 PE=4 SV=1 ---LFSPEFIFTDLEVKTKEECLKIMSQAMEEKHVVTEDFYDSVMDRESKTTTTIGNGVSLPHGSP---TAVNESKVGIAILKNPIMWDNE---QVQVVFLLAFRlstRDeiSRIQMFyKEYVTLIDSEEKLEKLKSMKSNIELYKYLI--- ->tr|C6B6T4|C6B6T4_RHILS Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Rhizobium leguminosarum bv. trifolii (strain WSM1325) GN=Rleg_6753 PE ---IIRPEHTFIGVSAPTKWRALQTIADKAAKAfSVDGQTILKALEAREKLGSTGIGNGIAIPHAAID---GMTSPRGLLLRFAHPLDFEAIDDIPTDIAFVLLFGennRGEYLNVLSAIARRLQSDGTLVAMRKARTVDEYYSDFIA-- ->tr|A0A1F5EXG5|A0A1F5EXG5_9BACT Uncharacterized protein OS=Candidatus Coatesbacteria bacterium RBG_13_66_14 GN=A2Y64_09070 PE=4 SV=1 ---LIPAGAINLDLTATKSHEALHEMAHLVVGQPGLPsnAEVISAIFNREMEYEAAVGSGAAIPHIMMA---GPEKPILAVGRSTNGIKFGRNGKEKVKLLFLLISPAenpHLHLHTISRIAKLLHRPEVRESL----------------- ->tr|A0A0A1MW87|A0A0A1MW87_9BACI PTS system fructose-specific EIIABC component OS=Oceanobacillus oncorhynchi GN=fruA_4 PE=4 SV=1 --DLLKKDVMILNLQGTSKEAVIDEMISSLYKNGIITeqASFKEAILAREDQSSTGLGDGIAMPHAKTA---AVTEPTVLFAKSEAGIDYDSLDGQPAHLFFMIAVPDdgsDTHLQTIAALSRLLMEPDFTGELKEAGTPDEVQALFAE-- ->tr|A0A1V5YYL7|A0A1V5YYL7_9BACT PTS system fructose-specific EIIABC component OS=Candidatus Hydrogenedentes bacterium ADurb.Bin170 GN=fruA_1 PE=4 SV=1 ---YLSADCVLPEVQTKIKADALKELTDLLIKNRKLKglEAALDQIMARESTESTGIGNGIAIPHARI---SGLKSLYCAMGRFKNGIDFSAVDRKPVYLVFAIFYPPtqqTTYLNFIATLVKMFKNKSHQEIIMKADSAADVFAALKE-- ->tr|H1B4G2|H1B4G2_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 6_1_45 GN=HMPREF0981_00095 PE=4 SV=1 ---LFDPKLFFV-KDFTEKEEIQKCLVDAA--SvLYQLDNLAEEIELREEFGSTYFGNGIAILHPMHLL---TDDSFIGEIILKKPAVWDTE-GNHVNLIFLVCIQKnnLEAFRAWDYLSPLLFNNEFKQEILSVEDYGDFKRICEE-- ->tr|R2TCV4|R2TCV4_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_00709 PE=4 SV=1 ---LFNEKLFYH-GRFSEKKEVLDKICSISVTKvGDKVFQLREAVELREGLGSSYFGNGIALPHPINPI---MAETFVSVILLKDELNWDTD-GNKVRLVMLVAIEKnnAKVFQLWNYLGKIIQEKGFVDRLIKDPTFENFKENLSQ-- ->tr|B9Y2V8|B9Y2V8_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00133 PE=4 SV=1 ---RFSSDLFWR-GQAKNRQEIVARLIAMASRSyHLP-KKFEELVLEREKLSSTYFGSQVAMPHPLYPI---TAQTFIAVAVLDKPVAWTED--QKVRIVLLVSTEMnnPKAFQLWPYLSSLISSPQQIHEILRESTYENFIAVFRA-- ->tr|A0A1C7HNZ1|A0A1C7HNZ1_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium I46 GN=A4V01_03675 PE=4 SV=1 ---LFSKSRFIS-KlSLHNKNEVIKALSTLSTNIvNE--NELYKSVTAREINGYTSYGNLIAIPHPETLL---TKKSFCSVAILTQPIPWSET--NYAQIIILCCASKqsSKDLQmLFNFISLLFNNKKEVEKIINNPTYDNFINSLQN-- ->tr|A0A1M6MLC0|A0A1M6MLC0_9FIRM PRD domain-containing protein OS=Propionispora hippei DSM 15287 GN=SAMN02745170_03475 PE=4 SV=1 ---IFYKDLFFI-SHGENREAIIRRLCQSATAHfHIEDGDLQNAVLQREQLGSTFFGNGIAAPHPISAV---SSDSFVAVAALPQPVEWDKD-KNMVKLVLMICIGKnnTKAFHLWNYLSTVFANRYFAEQLMVNPSYHNFVRLLKE-- ->tr|A0A1C5ZQN9|A0A1C5ZQN9_9FIRM Ascorbate-specific phosphotransferase enzyme IIA component OS=uncultured Flavonifractor sp. GN=ulaC PE=4 SV=1 --DLLLPGLMRIDVPCRNWQEAVYQSTQALELEGYVTEAYKHAIVRNLQEFGPAmvMFPGVLIAHASPA--DGCRKLGFGFMSLRSPVSFGNKSNDPVKLVFTLSVVDsSSHMEAMIQLFNMISEKPVRETLFRARTKQDVLSILQKE- ->tr|A0A1T4XY36|A0A1T4XY36_9CLOT Transcriptional antiterminator, BglG family OS=Caloramator quimbayensis GN=SAMN05443428_11514 PE=4 SV=1 --DLITWKTILLNAECSTWQEAIKLGTDILSENNYVDDRYYDAIMENFKNIGPYmvVAPGIVLSHARPE--DGVKKLSMSLVTLKNPVNFGSELNDPVKLIITIAAIDnESHLKALSQLMELFMNSNDMNEIYKAKTKEEIINIVTKY- ->tr|A0A143Z9W4|A0A143Z9W4_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system eiia 2 OS=Trichococcus ilyis GN=TR210_2732 PE=4 SV=1 ----FNPDHFYYINEPMTKEDLLQRMVGNLVNDHYAPDTFLASIMEREKLGQTNLNNMLAIPHPMSL---MALESVIPVAVIPEGIDWGDG--HSVKFVFLLSITKQDYentDYFYDLLLELMDQTEKQEQILNNPSFNHFMAVIEN-- ->tr|A0A0F5Z222|A0A0F5Z222_LISSE PTS sugar transporter subunit IIA OS=Listeria seeligeri GN=UQ68_12150 PE=4 SV=1 ----FFGADFFARSKLTSKSAILEEMVNSLRAQDIVGADFLSSVLERERLGSTVLGTGIAIPHPLGL---MAKDTKIVIRILDKPIKWGQK--QTIQVIFLLCISKNDYeeaINIYELLVGLVREE-YLEKLANLAGFKEFIRLAEE-- ->tr|U3GUT6|U3GUT6_9CORY Uncharacterized protein OS=Corynebacterium argentoratense DSM 44202 GN=CARG_05685 PE=4 SV=1 ------EDLVVFDVDVDDhPYAVLAFLSELLHEQQRCTdpQQLLSELWDRELKMDTGIPLGIAIPHCRS---TAITEPTVAMLRLAQGVDFSGPD-GPSDLIFCIACPatsGREHLKILSRLSRHLVDQAFVASLRSASSPDAVAARINQ-- ->tr|A0A142WP81|A0A142WP81_9PLAN Hemolysin C OS=Planctomyces sp. SH-PL14 GN=tlyC PE=4 SV=1 ---ALAAGNVLLEMKAETLEEAVRELASSIPPEsvPSFSQ-LCDLAGTHLASDVVDAANGVAIPHLRCP---GAKRPIIVIGRSTEGIRLRPEVETPTHLFFFVVTPAerpHAQSFFVEGMTTIARSEVIRGRLLIAETPVQVFEIIAA-- ->tr|M8DB60|M8DB60_9BACL Uncharacterized protein OS=Brevibacillus borstelensis AK1 GN=I532_21185 PE=4 SV=1 ---LENGLSVAGKMllselNDHLPFELVSEDVDTVGGWlySQLEEDiAVGASV-------ELEDHVFTVAQMDNH---RVTRVTIKQLVRPQAEKQEEPEMSAV-------------------------------------------------- ->tr|A0A1F9RWN5|A0A1F9RWN5_9BACT Uncharacterized protein OS=Elusimicrobia bacterium GWA2_69_24 GN=A2X36_13415 PE=4 SV=1 ---YWVPEAFDPKLEGASRSEVIARLLERLHAArPEFDRKaAYEAIWKREQGLTSAIGKELALPHGRLQ---DLNKPLIAIALSQEGIPFEAPDGRPVKIIFLILTPLkepAAQLRILANIAHLMSNAALRRRLQRARGPAQVGEILRS-- ->tr|A0A1G1BVH9|A0A1G1BVH9_9BACT Uncharacterized protein OS=Lentisphaerae bacterium RIFOXYB12_FULL_65_16 GN=A3K19_00610 PE=4 SV=1 ---FLVKEAVLTKMKARTHESAVRELAFALASHtRGLQPSmLADRAMRREREAPTAVGRGVALPHVRVE---GLPRTLVAYGNCAEGIDFKAADGHPVRHIFLILTPKenpREQLRALSRIAALATSDVLLGKLNEATTVDAVLAVVRT-- ->tr|A0A1F9VRW6|A0A1F9VRW6_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_59_9 GN=A3G41_05625 PE=4 SV=1 ---LFHEGVVVLDLKAETKKEAIAALVHALCKAkGLQNEHqIFSSVWGREISFSTGIGNSVALPHSAIA---GLSKFMLAFGLSRNGIDFQAPDKQKTHLIFMILSPMeqaGDYLQLLAKLSRLIRNSTIREQIMTTTRKETLLDLFDA-- ->tr|A0A1F5UXX9|A0A1F5UXX9_9BACT Uncharacterized protein OS=Candidatus Firestonebacteria bacterium RIFOXYC2_FULL_39_67 GN=A2452_11250 PE=4 SV=1 ---LISKKGVIADIGDIDKKEAVNRLIKKAAALyPEINEKeVSDEVWKREAMLSTAIGSELAIPHARVE----ISNTIIVFGRSKEGVEFNAPDKLPVKLIFLVLTSNsspIMQLRILAKIAKVAESYIFRQKIMEAKNEDEILNVIRL-- ->tr|A0A1G3D549|A0A1G3D549_9GAMM Uncharacterized protein OS=Pseudomonadales bacterium GWC2_63_15 GN=A2180_10220 PE=4 SV=1 ---QPGKLLVRGDTplfklERLLEIDLDHVEAETLAGLvyETLKRVpDEDEVL-------QVDGLQIVIKKMRGP---KI---VLAKVLRFPG------------------------------------------------------------- ->tr|A0A1R4R4P0|A0A1R4R4P0_CLODI Probable licABCH operon regulator OS=Clostridioides difficile GN=licR_5 PE=4 SV=1 ----FFDKNLfIVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMEL---SSIRTKICISILNEPIYWSED--STVKLIMMLAINKDDYikiNSIYDILLKIIHDNDIRDSISNCNDFDNFLSIIKS-- ->tr|K1ZMT1|K1ZMT1_9ZZZZ Uncharacterized protein OS=groundwater metagenome GN=ACD_62C00363G0005 PE=4 SV=1 ---ALAIESIHLNLKADNANDAITQALSRTPQEVLplSPKQIIQALTDRGHQIVVYLGDGIGLPHARVE---GLKKPFLMFLRLKKGITCESSH-DKARMLFVLLTPAgqpRTHQKILAALATLlQESEYVKDRLLTARTPTQIMDVIRT-- ->tr|Q17V80|Q17V80_HELAH Putative integral membrane protein with haemolysin domain OS=Helicobacter acinonychis (strain Sheeba) GN=Hac_1750 PE=4 SV=1 -------EEGVFELEGMLDLESVEEVLH------IqfDKE----------CEQVTLGGYVFS-LLERMP---MEGDTI-----ISHGYAFEVLSVDGARI----------------------------KRLKAIKENKEED------- ->tr|A0A1G0Z667|A0A1G0Z667_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_07935 PE=4 SV=1 ---ALTVDRVLLDVEGKSIIEAAEYALGRLNPNDLpmPTEKIMLSILEREKLMSSYVGQNIAIPHARLK---SLARPIVVVGRLKEPFPSPVPS-ETVDLIFILLTPAdipRVHQVLLSHIAQMLDSDFLSDRLINAKKPGELFEALKT-- ->tr|A0A1G0Y3J8|A0A1G0Y3J8_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_49_21 GN=A2X48_03015 PE=4 SV=1 ---RLTTDRVLLDVEGSSITSVAENALKRINPSDLpmPVETIMLSVSEREKIMSSYVGKNIAIPHARLK---SLARSVVVVARLKKPIPSPVPN-ETIDLLFILLTPAdtpRIHQALLSHIAQMLDSEFLADRLINAKTSSELFDALKT-- ->tr|A0A1M6N9Q2|A0A1M6N9Q2_9BACT Hemolysin, contains CBS domains OS=Rubritalea squalenifaciens DSM 18772 GN=SAMN02745181_2784 PE=4 SV=1 ---N----EQEFVVEG-------SITLNELSDHEPevDIE----------SGEVTTVGGYITQQMGRIP---EPGETLDILGYEAK---VTSTDGRRVGQV--HFRKFaeaESSEGAEEEVA----------------------------- ->tr|R6YSD2|R6YSD2_9ACTN Transcriptional antiterminator BglG OS=Collinsella sp. CAG:398 GN=BN642_01480 PE=4 SV=1 ---YLPRNLFFAHEHFEGKQEAIAVLVARMRaaYPDEIPENFEELVWQREEAAPTSFGNLVALPHPLFAV---STMTLVAVALLDEPIEWGTE-TGPVQAIFLMSFSRlpETRLdGFYRPVASLLNDGAAIEELLRTQRYEQLIGELRK-- ->tr|F2N8U7|F2N8U7_CORGP Transcriptional antiterminator, BglG OS=Coriobacterium glomerans (strain ATCC 49209 / DSM 20642 / JCM 10262 / PW2) GN=Corgl_144 ---FFKKSLFFPHMSTGTKEEALDYLIDRVAEREPVHEDFRNLVWRRERLVATSFGNGVAMPHPLEPA---AETTIVCIGLLDEPVAWDDS-GCDVRAIFLVAFAPdvDDSLkSFLSVFTDILSSARDIDLLVQHQSWKTFADIVAS-- ->tr|A0A1Y3XML8|A0A1Y3XML8_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_08235 PE=4 SV=1 ---FFREELFYPHLKAHDEAEVLDMLCRNLASIGGYGPTLRELVQAREDLMSTAYGNGVAVPHPLEAL---KGNTLACVALLDEPVAWGQE-GVSVDTVLLVAYGTddVSEMsEFHRVVVNLLFDNDGTRRLREIGDFESFSSLIGE-- ->tr|A0A243W329|A0A243W329_9ACTO Uncharacterized protein OS=Actinomyces sp. CtC 72 GN=BW737_04810 PE=4 SV=1 ---VFSPELFVPHLDARTPHEAIEVLTQCARTRYDLPAVFLDSVLRRETLAPTDFGNRVAMPHGEVAM---SEETFIAVGVLDEPIRWTR---NLVQVVCLVSISTreGKDLqQFYQDLSRYLMSEEHITTLIKSRDFSAIVRSIRE-- ->tr|A0A1V6DK19|A0A1V6DK19_9BACT PTS system fructose-specific EIIABC component OS=Verrucomicrobia bacterium ADurb.Bin122 GN=fruA_2 PE=4 SV=1 ---LLDPSRIQLQVQSTRRTAALNEVARLLSGHPDVlnYDGFYQALLERDRLDTTCLGNGIALPHARTE---HTKAIVMAVGRSTTGVRFENSGscGDTVHLMFMLGTPKnkpGDYLQVVSALCKLLKDASQREALLAATTPEEFIQLIV--- ->tr|W5XR64|W5XR64_9CORY PTS system, fructose-specific IIABC component OS=Corynebacterium casei LMG S-19264 GN=CCASEI_04140 PE=4 SV=1 ----IADDIVFLDAEFSSRDDAIAALVGAAAEAGRITnaDDVVAAALAREKQHSTGVDHHVAIPHARSA---AVSKPTLAFARLSEPgVVWAEGE-KPSRLISLIAMPEdagKAHLKLLSKLARHVMNQEFREELYAAATPADAVNKINS-- ->tr|A0A1V4R4A3|A0A1V4R4A3_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. 4484_143 GN=B1H06_06705 PE=4 SV=1 ---IIDKNLIVIDPPVKNKKELFEGMVNHAYSHDYILneKKFLDALLEREKMANTELIQGIALPHARSS---VTEKLFLSIIIIKNGIDYDNPDLGPVKIIFFFGCDnnsNKEYLQLLAKSNRLLKTAGFHSRLLACSTVEDVLALMNEY- ->tr|A0A0P0RDT8|A0A0P0RDT8_9BURK PTS IIA-like nitrogen-regulatory protein PtsN OS=Paraburkholderia caribensis MBA4 GN=K788_0005709 PE=4 SV=1 ---LLSPGNVLLDTAAVDRAALFAQVGAFCETHyGVPAGQVIEGLNTREALGSTGLGQGVAVPHSQI---AGLLTAVVLYVRPRMPLDFDAPDAKPVRDVIALLVPegaNTMHLNLLADVAQRFCDQHFRERLHACGSASEVCRLFSSA- ->tr|A0A069PV52|A0A069PV52_9BURK PTS IIA-like nitrogen-regulatory protein PtsN OS=Paraburkholderia glathei GN=BG61_32950 PE=4 SV=1 ---LLSQDDVLLGLNIADRPALFAELGHFFEQRcGLPATTTTAALAAREELGSTALGLGVALPHGHI---QSLNRPMAAYVCPADPIAFDAPDGQPVKDIIVLLVPewgNSMHLHLLADVAQRFCDHHFREQLHACADVRAVSELFRGY- ->tr|A0A163P3E1|A0A163P3E1_9ACTN PTS sugar transporter subunit IIA OS=Propionibacterium avidum GN=A2U93_08085 PE=4 SV=1 ---FLDPTLFFTGGSFDSWRETLDFMCEAMERNGIVPDGFRESVFLREGYSSTVFFRRFAVPHAMDF---LAYETKIAILIPSTPIDWEASD---VSLVLLLAINEgdyDDFVRFYQPLIRVLYDQELFTELRSISSYHEFMKFLDK-- ->tr|A0A0B7NXG8|A0A0B7NXG8_PROFF PRD domain protein OS=Propionibacterium freudenreichii subsp. freudenreichii GN=PFCIRM138_09570 PE=4 SV=1 ---FLSPELFFRDLEFASARETILNLCGHLQEAGVVPGGFTQSVLLRESYSSTIFAQRFAVPHAMEF---MASETKIAILIPKKPIDWGEdSR---VSMVLLLAIKNddyESFVAFYQAFIRALYDPDVFSRLRAAEGYVEFCRVLVD-- ->tr|U2N4E0|U2N4E0_9CLOT Transcription antiterminator OS=Clostridium intestinale URNW GN=CINTURNW_2658 PE=4 SV=1 ---LYKKDYFEIIEGHIEYRKILEDMSQKIENSGYGGENYSQYVMQREDYLSTIYLNGVALPHPIQ---MCARKNLISVAILKEPCIYEG---KEVRIIFMVSLTKDgyeLLKDVTKRLYEIMNKDELVEELCTAKSYEQFMAVLNT-- ->tr|A0A0X8GYW6|A0A0X8GYW6_9FIRM Uncharacterized protein OS=Erysipelothrix sp. LV19 GN=AOC36_02885 PE=4 SV=1 ---LFKEALFTVYHN-LSYCDIIKNMAQKIVDIGYAEPSLVDSVMRREEVMSTIFLNRVATPHPLE---MSGVTDCIHIGIVSED---LE---EMPKVIFLISLKKGqltLHQRISKFVFEVMSDADLVNNLHKANNYLEFMLLLNE-- ->tr|A0A1L8SWS7|A0A1L8SWS7_9ENTE Uncharacterized protein OS=Enterococcus devriesei GN=RV00_GL001691 PE=4 SV=1 ---LFSQSLFQIETH-RAYSDILVDLADQVEE-QVAFAGYKDSLMERENYLSTIYQNGIAIPHPLI---MSGKENRLAVCLLPEGTSGTE---RSPKIIFMVSLKAEqldVHQIISKELSKLMNHPAAIKTLVESKDYHEFYYTLKR-- ->tr|A0A1L8WX06|A0A1L8WX06_9ENTE Uncharacterized protein OS=Enterococcus raffinosus GN=RV13_GL000885 PE=4 SV=1 ---LFDRKWFQILDPPAEYLTLLENEGARLEELQWAEQGFKQSVLEREKLIDTIYQHGIAGPHPME---QAAIKEVIDVILLKRPLTYRE---KQVRVIFLINIKKDhlnLHKEISRLMIKMMDDPTLDTQLTKITNFQDFMSYMKS-- ->tr|A0A1L8V7R4|A0A1L8V7R4_9ENTE Uncharacterized protein OS=Enterococcus malodoratus GN=RV07_GL004091 PE=4 SV=1 ---LFEPEWFQIEEQADNYLQVLENEGARLEKQGWVEQGFKQSVLNRERMIDTIYQQGVAGPHPME---QMAVKEVIDVILLKKPLMYRD---KQVKIVFLINIKKDhlnLHKEISRLMIKMMDDPMLELQLTKIKNFQDFTSYMKS-- ->tr|A0A223K4T6|A0A223K4T6_LACSK Uncharacterized protein OS=Lactobacillus sakei GN=LBS_07600 PE=4 SV=1 ---LLKPNLFSVETI-QNYDVLIKKMAEKMMSKGYADDNFQKNVVLREQYMSTVYNNGIAMPHPIE---MKGKQSAIAVSVVKPELRVGK---RVVRLVFMVCLAKEdfhFYSNISNGLFQLMQDNHKISDIYHKPDLQRIINIFKE-- ->tr|A0A150LPJ3|A0A150LPJ3_9BACI Uncharacterized protein OS=Anoxybacillus flavithermus GN=B4168_1017 PE=4 SV=1 ---LLGEDRFFILDHNKDYWENICVMVDSLYEKGYVDADFKKRLKEREEKGTTIFDSYIALPHTLNC---ASENVVLSLGVFPRPLqTFSGK---EIKLVFLLGVPQHMkqdsslLVKIYDEIITVANDRQLINRLALSKSYDEISHLLEHN- ->tr|C5USF2|C5USF2_CLOBO Putative transcription antiterminator OS=Clostridium botulinum E1 str. 'BoNT E Beluga' GN=CLO_3391 PE=4 SV=1 ---MLDKKLVFYLNK-NNFMDNLEDMLDSLIKSNIVSNEYKNRVIAREKKAGTAFGGYIALPHAVDE---KVNSVIVSYGILDNLIMVDGK---EVGLIILLVIPSESqnsqdvIVKTYQEIIDLSSDKKIVQKLIKSKNYKEFKEVLGRR- ->tr|A0A165X218|A0A165X218_9BACI Transcriptional antiterminator BglG OS=Aeribacillus pallidus GN=AZI98_13955 PE=4 SV=1 ---LLNKDKFFVLDTNKGYHENVNDMIDVLVKKGYLDEGFKERLREREEKGSMVFDRYISLPHTVNY---KSNQIEMAIGVFPEKAVVDGK---EIKLVFLLGIPEKAdndaslLIKIYDEIIKIASDQKQVEELADAASYEDFTKCLEQA- ->tr|W7KTP0|W7KTP0_BACFI Transcriptional antiterminator BglG OS=Bacillus firmus DS1 GN=PBF_18169 PE=4 SV=1 ---LINKDKFFHLDSRKSYQENVMNMVDHLVDKGYLDAGFKERLTDREAKGSMVFDRYIALPHTSNT---ATDKIELSLGVFPENVLADGK---EIKLVFLLGIPKQTdydaslLVKIYDEIIRIAADDQLIDQMAHSSSYEELGKCLIYA- ->tr|F3A4X1|F3A4X1_9BACL Uncharacterized protein OS=Gemella haemolysans M341 GN=HMPREF0428_01779 PE=4 SV=1 ---SMREETFFKCDSKKTYADNIDFMIEELIKQYLVDDKFLERIREREKKSSMIFEKNVAFPHTINK---LGDDLIIALGVSEKGF-KDNE---DLKLIFMACVPEG-ekngliLAKTYDELISIIKDEKLITDISKIDNYDLLVNYFIKN- ->tr|A0A1M5ZAK0|A0A1M5ZAK0_9CLOT Lichenan operon transcriptional antiterminator OS=Clostridium intestinale DSM 6191 GN=SAMN02745941_02712 PE=4 SV=1 ---SIPQEQFFIIKR-KDYVGAIDYMVTNLSEVLTLDKDFKKRLIERENKSPTAFDNYVGLPHAVNY---GSDKFSISMGILEEPIVWGKN---EVRLIIMLIVPDENsidpdmVISVYEEILKICQNKKFIEELCKVRSYKEFLDLNRKE- ->tr|A0A1M4W0A2|A0A1M4W0A2_9FIRM Lichenan operon transcriptional antiterminator OS=Alkalibacter saccharofermentans DSM 14828 GN=SAMN02746064_01119 PE=4 SV=1 ---ATKPNLFFKTNL-DDYIDILKEIIGKLFNQREVDEGYLDRVLDREATYPTTFANGVAMPHAINK---GGERLMISIIIPEKEVNYENS---AVRIIFMLLIPEIMdespevLIKTYEEILKICQNEDLLGKVINAKDYFELTNVLVKE- ->tr|A0A221TMH7|A0A221TMH7_CLODI Transcriptional antiterminator OS=Clostridioides difficile GN=CGC51_12505 PE=4 SV=1 ---LLDEDKFMILNE-KTILASLEKMMDHLMDLGCIDEKFRKNIVNREEKSPTVFDKGLLFPHSINE---KSDKFLMAVGILEEPIEYANR---SIKIILMTMFPCENkidsdlLVKIYEEVLKIGQDVKLTNKISKCRTFLEFKKVLLKN- ->tr|A0A1F5YM94|A0A1F5YM94_9BACT Uncharacterized protein OS=Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11 GN=A3F83_02290 PE=4 SV=1 ----FNASNVNLDLEAQGKDEVLLELINLLHLDEKAKEMLFKMLKKRENLGSTGIGKGFAIPHCRSL---VVDKLNVAFARQRQGIDFNSIDDKPAHYFFLIVAPPveisNYYLPVLGKVAQFCKISDITSRLDKLTKVEDFLKLLAD-- ->tr|A0A1G3QNM8|A0A1G3QNM8_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_16_49_21 GN=A2W19_17170 PE=4 SV=1 -------------TRADEKHLVIKEILTMLEDMRRIDsaERFYAHIIHRESLENTGIGRGLAIPHIRTE---TVNDLISVFAVSRNAIEYHSYDKIPVRYILLSIVPMeesTKYLYLIGMISWIFMDEKRKKPLGQAENRTQIYNVLKKN- ->tr|A0A1V5W984|A0A1V5W984_9SPIR Nitrogen regulatory protein OS=Spirochaetes bacterium ADurb.Bin218 GN=ptsN PE=4 SV=1 -------------INSTEKQPALKELLSELQTQSLIEnsNRYYAQIAHRESLENTGIGNSLAIPHARTE---TVKELITILGICNSPLEYQSIDGRPVRYILLSLFPTslsTKYLYLIGMMARIFNNPENNSFLSQEHSPEEIYYFLNEK- ->tr|H3NQM9|H3NQM9_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_01640 PE=4 SV=1 ---ILKPEFMRFEIEAKDWKDSIVKSSRILLENDIIEERYTDAMIKNIEEYGPYivVSKGVAIPHASSE--EGVKKTAMSLIKLKNPVPFGVEGLDPIQYVISLSSLNNEHFYAFFDLVNGLQNEEIKQEFISANSSSDMEKVLKK-- ->tr|A0A1J6EXE8|A0A1J6EXE8_9STAP Transcriptional antiterminator (Fragment) OS=Staphylococcus equorum GN=A4A34_04945 PE=4 SV=1 -----LIELFAIKSNVESKDELLSEIESDLKALHYIKSDFFEKVNEREEVATTAYGNLIAVPHPVTP---SAKQSFIYIVKLDKPIQWGDKD---VQLVFCLGLKSQttvDMEPIFKRISHIINDFSLVVELLNQSNEKDLKETYFD-- ->tr|A0A239V294|A0A239V294_BACPU Transcription antiterminator BglG OS=Bacillus pumilus GN=licR_3 PE=4 SV=1 -----KKELVFTKRAFQTKEEVITFLTKKVIDMGLAPAELTPSVMEREEAAPTSFGHYTAIPHPMTP---LTEETFWAICSLEKPIIWGEKK---VQFVCLLCVEKEnakDLKGMYRLLGELVHNVKFIQHLIACDTFEDMLDIMYK-- ->tr|U2UT44|U2UT44_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 component OS=Olsenella profusa F0195 GN=HMPREF1316_0722 PE=4 SV=1 ----LRPDFFKLNFYPGNYDELIAAMVLDCLDKGLVGEGYLEKVLEREALSPTVFDNLVAVPHTVEP---AALRSFLYLVINDRPVAWGQSS---ANIILLLGISEndrESFTNFYSDFLSILSNAKNASELIGSVSYEDFMRRLT--- ->tr|A0A223L845|A0A223L845_BACCS Transcriptional antiterminator OS=Bacillus clausii GN=BC8716_18185 PE=4 SV=1 ----FDKELFMKNVYLDSDEAYIEFMSNLLHKKGYVSKEYGKSVLERERMSSTAFNNNVAVPHSMHM---DATKTGICMIILDRPVTWGKEK---VQVIVMISINKqqrELFSPFFEGVINILSEWRNVHELIKAKDYDDFMDKMM--- ->tr|Q6Y9A9|Q6Y9A9_BORHE PTS system fructose-specific IIABC component (Fragment) OS=Borrelia hermsii GN=fruA2 PE=4 SV=1 --DLFSKKLILLNYEAKSKDDVIEKMADMLNENGYLSnkENFITDIKKREEISGTGLEEYIAMPHAKG---NFVAKHGIAILRVtGEGFDFDASDSKPSRLFFMIAVPanttGDTHIKTISYLNNIFNNEILRQEIMSTNDISRFLEILL--- ->tr|A0A1W1X1Y5|A0A1W1X1Y5_9DELT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Desulfacinum hydrothermale DSM 13146 GN=SAMN02746041_00387 PE=4 SV=1 ---FLDDDLVVLDLQARDRMSALREIMEKIPQNGRIRnkEKALRDLLDREALSTTGIGGGFAVPHVLSE---EANLPTLLFARSEQGVDFQAKDGQPVHLILVAfANPRkkNFFVQCLYHAVQILKDPEQFQRLMQAATPEEVLSVLGRR- ->tr|D5H7D5|D5H7D5_SALRM Sugar phosphotransferase system protein OS=Salinibacter ruber (strain M8) GN=SRM_01019 PE=4 SV=1 ---LLDPEHVRIGLAEPSKNAVIDALVDVLAGHGAISrlDDVRAAIFAREEKMSTGVGKGLGLPHAKTPA---ASNTVAAFATTDEPVDFGAVDDVPVQILLLLVGPEehkSQHVKILGRISRLVSREPLRERLLDAETPKAVIKTLREG- ->tr|F2B1U3|F2B1U3_RHOBT Sodium/hydrogen exchanger OS=Rhodopirellula baltica WH47 GN=RBWH47_03749 PE=4 SV=1 --DFLQENRIMVDLDGDTE-EIFQKLTNLLYATTPmstPQEKFLESVRARESSQTTCLGTGLMIPHAIIDEPG-DNEVKGVLGISKKGIKLNTPDGRAVHAVLLLATPEssrKRHLEILSAFATAItRDINIREQLYRSRSAAHAYEVLH--- ->tr|M5UL15|M5UL15_9PLAN Sodium/hydrogen exchanger OS=Rhodopirellula sallentina SM41 GN=RSSM_00004 PE=4 SV=1 --DFLQEHRITVGLTGDDREATVRELTSQLYATSKmevNQEEFIQRVMARDAEHSTCLGNGLMIPHAILEDGE-GREIRGVLGISPEGLNFDTPDGRVVHAVLLLATPEverSRHLQVLSAFATAItRDANLVEQLYHARSPAHAYEILH--- ->tr|A0A0J8GC81|A0A0J8GC81_9LIST PTS system IIA 2 / PRD domain protein OS=Listeria fleischmannii 1991 GN=X560_1126 PE=4 SV=1 ---EFKEQLIVTKKHVNTWQQAIRLGTEVLFQTGCIEKRYTEKIIQNLKAFGPYmvIAPGIVLAHASPK--DGVLKDSMAVTVLEEGISFFDRYGEPVRLIFTLAFESKEARRLVEQLMKVVLNEEQVSRILSAKSHKDIYNYTKS-- ->tr|A0A0Q3WVB6|A0A0Q3WVB6_9BACI PTS fructose transporter subunit IIA OS=Bacillus shackletonii GN=AN964_02515 PE=4 SV=1 ---IFSSETIVYGEKANTWRQAIALGTNNLLSMNCIESRYYENIIKSITKYGPYmtVAPGVVLAHAGPD--DGVLKDSLAVTVLNKGVSFYDRYNIPVQVIFTMAFHSKGTHLLVERLAQLALNSDKVRLLTEASSKEEIYQLVKA-- ->tr|A0A221M9L4|A0A221M9L4_9BACI Uncharacterized protein OS=Virgibacillus necropolis GN=CFK40_04490 PE=4 SV=1 ---KFGEEHITINKGKLRWDEGIKLGTSALIDRTYVTPNYENKITHNIRKYGPYmvVAPGVMIAHAGME--DGVIEESMWLTILPYGIRLNDRFDEPITVIFTLAFKNKGTRHLMEKIANLALNKEKMNHIIELSSSEEIYDFVSA-- ->tr|A0A0V8QCH9|A0A0V8QCH9_9FIRM Uncharacterized protein OS=Acetivibrio ethanolgignens GN=ASU35_13315 PE=4 SV=1 ----VDTEHIMIVRKKTERDAILKEACEILFDGGYVKKEFFDDVIKRELIESTAIGNGVAIPHGMPE---NVIKPKVFLIQLKYPVNWEG---KMVRTIFLLALNFnniATTKAFFSDFTRITGSEERIHAIQKCETVEEIWDLLKD-- ->tr|A0A0D6DX31|A0A0D6DX31_9LACT PRD/PTS system IIA 2 domain-containing protein OS=Lactococcus piscium MKFS47 GN=LACPI_1119 PE=4 SV=1 ------------ALNDLTPVMIRKRLYQRMQQADYVDQTFLCEVEKLEKMSPTSFPSGIAVPHAVA---RVAFKSGVSIMTLRHATIWEN---YPVKLVACIAINQadaRVFNRFFEQFIMLVSDDMNAKKLSSCSSHADFISTLKA-- ->tr|U3BJS9|U3BJS9_VIBPR Uncharacterized protein OS=Vibrio proteolyticus NBRC 13287 GN=VPR01S_05_01730 PE=4 SV=1 --------------ETEDKNHLLAQSAMCANPS--RQDVLYQALQARETISSTLIGQALALPHIMHS---DVTVPTMVFQRPNAQVVWHQ-NKAPAHLVITLFIPsptDRQTLIPFTRLTRWLLSEPHQTLLLDNLDDFTLRIIIS--- ->tr|Q5DZL5|Q5DZL5_VIBF1 PTS system, IIA component OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=VF_A0711 PE=4 SV=1 --------------AVLSKFEILKGLSQLIYPK--ESDELLLALIKREERSSTAMAKQIALPHVISP---YVEKPTIAIIRSDYPVDWAS-KMGDVNVIIALVLPekpTKEMIMAATYLTRSLLSEDFSQRLVHTRQPKGLQALIL--- ->tr|F0LNV1|F0LNV1_VIBFN PTS system, nitrogen regulatory IIA component OS=Vibrio furnissii (strain DSM 14383 / NCTC 11218) GN=vfu_A00075 PE=4 SV=1 ---------------LPDKRSALTHIAALANPN--ATSDLLTQLLARECISSTAMAGGIALPHVVSE---HIQRPCFIVFSLDEGLDWQS-AHEPVHLVCAVLLPaalHREWLIAVTRLTRWFIADTSAHLLLSARREETIESIVL--- ->tr|A0A0F4NYD9|A0A0F4NYD9_9VIBR PTS system nitrogen regulatory IIA component OS=Vibrio neptunius GN=TW84_15800 PE=4 SV=1 --------------EIDTKSAAFSLATKCITSS--NPALICEQFAQRELTSSTAIGHGIALPHIMSE---AIDIPSISIVSLTEELDWNSPVQGGVSMIIAIALPhnaSRDVLLAFTRLTRSLLDPDYCQLLRTSHEPQALKALLT--- ->tr|M4U166|M4U166_9GAMM PTS system, IIA component OS=Psychromonas sp. CNPT3 GN=PCNPT3_00980 PE=4 SV=1 --------------TQYNKNKILLSLTRIISKS--SYKPLLSALLAREKISATGIGKRIAMPHILSD---LVDEPWVVVLHSEEDIDWHS-PLGDINLVLALIIPrnaSKDIFRSVISLSRALLDPNFTDLLLQTRDPQELETLLL--- ->tr|A0A1E5CIQ4|A0A1E5CIQ4_9GAMM PTS nitrogen regulatory IIA subunit OS=Enterovibrio calviensis FF-85 GN=A1OS_13850 PE=4 SV=1 --------------SNLDKHALLAEFALRVadnenrEDT--TQEALFNALYTRENVSSTCMGNGVALPHVMTP---LVSQIHVFIASTAQPLDWLS-KRGEVTRVIGVMLPkppVREHIVAFSTFSQQLLDKTFCRYLEENTSLDIVETIVL--- ->tr|A0A0R1U3K1|A0A0R1U3K1_9LACO Uncharacterized protein OS=Lactobacillus pantheris DSM 15945 = JCM 12539 = NBRC 106106 GN=FC50_GL001224 PE=4 SV=1 -----EPKLFWHLSGHTTKDEVLKPAIDEMRKQQVVNDNFYDEILERESMGSTSFK-NIAIPHPMS---FNSPKTKVAVILNEDGITWDGA---EVNMVYIISISEkykDEFRSIYENLMDFLSDDQKFKSILESRDLNSFYERL---- ->tr|A6DH31|A6DH31_9BACT Nitrogen regulatory IIA protein OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_13897 PE=4 SV=1 --DLLNPKLILCDLQSESHEMVYLEMLEALKGQCkdIAePRDILKDILEHESLVEMPYNSGFAIPHTRSA---GVNDLHLVLGIHKQGIKLQEHDLEKSKIIILFLVSKetsKIYLLILKALARYFSNPGVSDQLAECATAQEVTDVFQK-- ->tr|A0A1G0YZ22|A0A1G0YZ22_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_44_16 GN=A2017_04880 PE=4 SV=1 --SILNPDLFFSGIPADNRHAIYKNMLEKATRGIkqSIdPEKIVSEMIKREDVFSIPYEKGVALPHLRSS---MFDDLYIIVGILDSSILLKDNDKDLSRVIIMSLISEktsDTYLKALSAFSRYIIkNGGVVSSLTSCHDGNEFNALLDA-- ->tr|A0A1G0XLD5|A0A1G0XLD5_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_45_14 GN=A2020_04745 PE=4 SV=1 --SILNPDLFFKGIPVGDRQSIYKSMLEKAAGEIkqDIdPEKIASEMVKREDAFSIPYEKGAALPHLRSP---LFDDLYIIVGIPDSPVLLKNNDKDLSHVVIMSLVSEktsDTYLKTLAAFSRFVIkNGGSVSRLTSCRDGNEFNALLDA-- ->tr|A0A1F4YLK2|A0A1F4YLK2_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium RBG_16_53_22 GN=A2W25_03105 PE=4 SV=1 --DFLDPDLIDVDIKAETKFDAVKELADLFCRKFaDSdKQAILDAVLEREDLGSTSFGRGFAFPHARTD---VVTDLHIAIGIIKEGVKDKGPDDTPIRVICLLLTPRnisKLYLQTLSGLANLARRQGMLECLSAAKSPRELIAIIDE-- ->tr|I4C4T7|I4C4T7_DESTA Universal stress family protein,osmosensitive K+ channel His kinase OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DC ---LISSRRIVIWNQPVEKEYVIRTLVEVAAKDfETCDaEDTIKAVLDREKLGSTFFaNEAAAIPHARIK---GLSSPIISLGLTKQGILQDEAI-SPIGLVFLILTPaeiPSSQVEILALVSRATKDGHLYDRVAESDNPEELLSILRE-- ->tr|E1YG16|E1YG16_9DELT Putative uncharacterized protein OS=uncultured Desulfobacterium sp. GN=N47_J04910 PE=4 SV=1 ---FLKKMSVLIWNKRIEKEEAINRLLDACCSEkTELKKSAWIALLEREKQGETFVGEDVTIPHARII---DLQTPLVALGIGKAGIQDQRSE-RSARIMMLLLSPadsPESHLSMLATISKMARSDKWRKEVLSANKSSDIIKLVAE-- ->tr|A0A1X3HZN0|A0A1X3HZN0_ECOLX PTS system, fructose-specific IIA component OS=Escherichia coli M056 GN=EAMG_04644 PE=4 SV=1 -MAALTASCIDLNIQGNGTYSVLKQLATMALQNGFITDshQFLQTLLLREKMHSTGFGSGIAVPHGKS---ACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGVPQsgeEDQVKIIGTLCRKIIHQDFINQLRQ-GDADQVLALLNQ-- ->tr|A0A0Q3W0M4|A0A0Q3W0M4_9BACI Uncharacterized protein OS=Bacillus sp. FJAT-25509 GN=AN960_18690 PE=4 SV=1 ---LFHTELFYIEESKesFDYKAFIKEKAKSVVELGFAAPNYPALVVDREEKISTILQYGIAAPHALK---MVAIQDSISVVIFKNPPTIDG---KVVQILFLINLRAGdlfLHKELSRLFLHLMDHPETKQKVLKSNNFNDFQYEISK-- ->tr|N9Y3Q8|N9Y3Q8_9CLOT Uncharacterized protein OS=Clostridium colicanis 209318 GN=HMPREF1092_01712 PE=4 SV=1 ---KLDDVLFKRRKGGkdINYKNFLREEAKMLIKKDIVLEDFEELVLLREEKLSTAYKNNIAAPHGIE---MNAKKNVLSVTVFDNPIEWGD---KKITIVILIGMKKGslnLHRVIANKLFRLINDEEERNEISKCQSSEEFIKAFKI-- ->tr|A0A1Y3VII7|A0A1Y3VII7_9FIRM Uncharacterized protein OS=Faecalitalea cylindroides GN=B5G15_07090 PE=4 SV=1 -MKVIDHNFIFIDTDFKTQKELFLFLAKQVFSskRGNDLDKIVEGFYEREQEFSTAMDNYIAIPHCRNE---NILQATVIVVRNKTEIKWTDNE--NVKLIFALLVPGsnenQMHIRILAQVAQLIMEEDFIDLVNKAKGDDQIYQRLS--- ->tr|A0A011RNX5|A0A011RNX5_9LACT Transcriptional antiterminator, BglG family OS=Alkalibacterium sp. AK22 GN=ADIAL_0871 PE=4 SV=1 ----VKEAFVQVADRADSFKEAISLALKPLVDHKYIEQAYVSEVIHAFAENGSYmfVAEGIAIPHARSE---QVKETGFGILKLHEPVRYSDN--QTIDMLICFSSRDnLGHLDALINIVDYVKTPEFLSALRSIRTADELArHIL---- ->tr|A0A1L8PHB8|A0A1L8PHB8_9LACT Uncharacterized protein OS=Alkalibacterium sp. 20 GN=AX762_01720 PE=4 SV=1 ----VPKSHIQIVESVDSWKEAIVIATRPLVDNSYVAESYIENVTESFEKYGYYmfIGDEVAIPHARSDK--DVFKTGFSILILKNKVQYSED--SAIKVLICFASMDnLEHLDTLVNLIEVVKSDEFKQILNQNITEEAVFQLI---- ->tr|A0A0G7ZNG7|A0A0G7ZNG7_9MOLU | fruA / EIIABC-Fru |:139640 Forward OS=Candidatus Hepatoplasma crinochetorum GN=HEPPS_04980 PE=4 SV=1 -------EKLIVDKDFNSSEEVLHEIANLLKANNFIEDssTAYSNLLAREKQISTGVGNGIAIPHAEIK---DLEEPKIAVIRSKKGIEWNSIDSKKVNLIISILVPKenrEKHFEILTKLSSSLVEAKNIEKFKNAN-AKELVDYIE--- ->tr|A0A1L8WVS3|A0A1L8WVS3_9ENTE Uncharacterized protein OS=Enterococcus raffinosus GN=RV13_GL001139 PE=4 SV=1 ---ILTVERIKLDQSCDSWQSAVEAAGQLLLADELITSEYIQAMIQMVVDYDSYivISPGVAIPHAEFS--HGAKKIGASFVRLAEPVSFNHQKNDPVKYVIAFSLPEGVSIgTCLYYFTEILATENFLALMDQCQSEEAVMNQLRK-- ->tr|A0A0F4LIB8|A0A0F4LIB8_9LACO PTS Fru IIA OS=Lactobacillus kimbladii GN=JF75_12790 PE=4 SV=1 -------------FDVTDQKAAFQIIADIVAPKMEVsKVTVLKSLLTREKTANTALVKGIAIPHIILEL--D-FTPWLLIIKSQTLVaDWDCLDDSKVNTLICLIVPRiikksNKSFKKIIQIIDKLADDNVIAEINKAESATEIVQILKR-- ->tr|V6Z2V6|V6Z2V6_STRAG Uncharacterized protein OS=Streptococcus agalactiae LMG 14747 GN=SAG0136_01325 PE=4 SV=1 -------------MEELTKDKALLKIALFLSKEMKTdTRCILNSIVERETIANTGLEKGIAVPHVIIEN--N-AISNahLAVITFYPPVlDWLCNDETAVDIALCIVLPKsydlkTKNIEKLTKIFKSLADEEFINSLQLKRNSIDVIRKLEN-- ->tr|A0A0R1T4P9|A0A0R1T4P9_9LACO Uncharacterized protein OS=Lactobacillus saerimneri DSM 16049 GN=FC54_GL000508 PE=4 SV=1 -------------LTGANKQEALQQLAHAAATTLNLdEIEVKATLMTREALADTALISGIAIPHIIIDK--E-FTPQICVGLLASPLeDWDCLDGTKVHLLLAFAVPQrtlvhQQEIREISEMITQLADEQFCWRVSQAQTVAEVSAILSE-- ->tr|B2KDQ9|B2KDQ9_ELUMP PTS IIA-family protein OS=Elusimicrobium minutum (strain Pei191) GN=Emin_1103 PE=4 SV=1 ---LLDADSVLLVKdPNTSKELLITQLSALACKDlSAEDaKDILERVLKREQGITTTLDTGLSIPHCRVD---ELDSFKAALAVIPQGIKDPLTDNITIKVMFLFLSPSnpaffQKHLQMLAELSEKFKD-SFISKLTQAAAPQEIIKIIKE-- ->tr|A0A1F9TWZ9|A0A1F9TWZ9_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_57_9 GN=A3J74_04815 PE=4 SV=1 ---YLSEQAILIVGSKRGKNELVGLLVNDLCREnGLLSpDVFLAKVLDRERGISTTLDTGLSLPHARMD---GLDKIIAAMAIVPGGMRDPQQADLIIRAMFLFFSPNkqeffPLHLQLLRSVSLLFQP-SFIDQVARAAGPAEAFKLIRD-- ->tr|A0A1F9W9M3|A0A1F9W9M3_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RIFOXYA12_FULL_57_11 GN=A2285_03740 PE=4 SV=1 ---IINPESIIFLEGRLSKEEVVRQLTEKILPAvSGViSrKALFDRVAE-VEKLNPVLESGFYIPHAKFP---DLDGFHAVLGITPEGFPDAAT-GLTVKAVLLLLSPHkpeffQRHLNMLSLLSQTFQP-EFIERLAALKDPAEVYALIQS-- ->tr|A0A1F9S8D2|A0A1F9S8D2_9BACT Uncharacterized protein OS=Elusimicrobia bacterium GWB2_63_22 GN=A2X31_01545 PE=4 SV=1 ---IITPENVVFIEGSPSKEEAVRLLTEKMLPQvGGIiSrKALFDRVAE-VEKLNQVLESGFYIPHAKFP---ELDGFHAVLGILPEGFTDAVT-GLKVRALILLLSPHkpaffQRHLNMLSLLSQTFQP-ELIDQLAALKDPVAVLALIKS-- ->tr|A0A0S8FT88|A0A0S8FT88_9BACT Uncharacterized protein OS=candidate division WOR_3 bacterium SM23_42 GN=AMJ83_04470 PE=4 SV=1 ---YLDKDRILLNVTAEKYRDMLVRMLETSAEQDK--LCVVDNILQREKIMPTAIGKGIFLPRAVLR---DKSKSEVIIATNPSGLSFEDYGPMQAYIIVLFLFSeKDDSAAILAQTLRLLSDDTLRSDILESIAPIDVIKAISEW- ->tr|A0A0K2LEW7|A0A0K2LEW7_9LACO Uncharacterized protein OS=Lactobacillus heilongjiangensis GN=JP39_10870 PE=4 SV=1 ----FPKDNFKVVDDKVERDDIFQTVCDELESKNVIPEKFSDKLKARENMSSTAFG-RVAIPHSMQ--M-IALKTQGYVVIAPKGILWNED-NHEVNLMFLLAVNKeNkqSYRNIFDDLSQIAVDPKNIAELVKARTYEEFIKQLTN-- ->tr|A0A0R2LH36|A0A0R2LH36_9LACO Transcriptional antiterminator OS=Lactobacillus kimchiensis GN=IV57_GL000186 PE=4 SV=1 ----FPKQNFIVSQEKLNRDDLFIQISSILEKKNVVKVGFAQKLIAREKMSSTAFG-SIAIPHSLE--M-IALRTEGFVVIAPNGIDWNSD-NHNVKMMFLLAVNEtNkqAYRNIFDDFSQITVEPKNIAILLKSKTHEQFINTLVS-- ->tr|Q8Y9A2|Q8Y9A2_LISMO Lmo0630 protein OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=lmo0630 PE=4 SV=1 ---LIGIDAIQITSESLTWQTAIQRATKLLSDNHFVLPAYAENIKQIqEELGFYSVkDEEFALFHGNDS--QLVQMNSMALLINEQPVMFGEK---QAKVIFILASKDkKEQIPAIITLTKMTYQTDFISKLEQAKNPIDADRIIKKY- ->tr|A0A1C0BYI1|A0A1C0BYI1_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_01200 PE=4 SV=1 ---ILTRNMVSLVEQDMEWEEAVHESAKILIDNNYISTIYEMNIIETmKNMGFYAItDDMFSLLHGDHT--AGVNRTGMSLIVNKKKVFFDDK---GVNLIFCLASIDkREHIPAVISLIRMVKQTDFINKAKMCDNTDELYDLLLEC- ->tr|A0A1W9VTR8|A0A1W9VTR8_9BACT Uncharacterized protein OS=Candidatus Cloacimonetes bacterium 4572_65 GN=B6226_01235 PE=4 SV=1 -------------FSPTSKIDAINQMAKLLKEKKIIPetEIITNAIFERELLATTGIGKGLAIPHCRVG---SVDRVIVVASYFEKPIDWNSMDGNPVDLAFMIITPQespELHLKAISKISKAVRTLDFRKEIS---------------- ->tr|A0A1G1Q3Y8|A0A1G1Q3Y8_9BACT Uncharacterized protein OS=Omnitrophica WOR_2 bacterium RIFOXYA2_FULL_38_17 GN=A2243_07535 PE=4 SV=1 ------------------------------------KEEAFAEAMQREELQSTGLGQGRAFPHVRID---GWKDFVIALGYCKEDLPFESLDDQPVFFICLMISSKdqpYLILKAMSNIIKFLNELENIRSLFENKTPAELADIFKNK- ->tr|A0A1Y0L006|A0A1Y0L006_9MOLU PTS system, fructose-specific IIABC component OS=Spiroplasma clarkii GN=fruA PE=4 SV=1 ---VIATENIYLDIKLKDQAEVFKFIADVAAKKGICEddEGLIAKLKEREEISSTGFENGIAIPHTQFE---KILKPTVLFIRTQTGVWWDSIDGQDAKVFFCILVPKsttqNLHIEILGNLAGKLLNEQFVELISTTKDPQQIVDAIG--- ->tr|A0A235BWV3|A0A235BWV3_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium JGI_Cruoil_03_51_56 GN=CH330_02130 PE=4 SV=1 ---------------ITNQKAVFQFVARRLAEQRLINnqEVLVEEFMKREQQGSTGVGHGIALPHVATE---AVNQIVVAVVRLNQPMEWDAVDGKPVHLLVMIIAPPdqrKLYLQVLAEVARSLNQPTIRDKVLKARHPAQAVRIIA--- ->tr|A0A1W7A9U0|A0A1W7A9U0_9STAP Putative licABCH operon regulator OS=Macrococcus canis GN=licR PE=4 SV=1 -----QPFLIFTNNTTSDRYKIIEEIGKKLIGQNLVQHEFIKSVAGREYLSSTCIGSGIAIPHGKS---EYVLKSSISVYTLNHPIDWGEE---SVDLVFLIALKEedKkYYQNIYRELHTIMQDKLLLRKIKTERSSLKFLKLFKDK- ->tr|B7C836|B7C836_9FIRM PRD domain protein OS=Holdemanella biformis DSM 3989 GN=EUBIFOR_00339 PE=4 SV=1 ----IQKEHVKVYPDTKELSELLQEMSQKLHESGFISdtKGFYEDVLLREKNYPTNLGSQMMVPHALF---TFADKTGIEVALLKKPLEHDGN---QVQLVFLLALEKkrNDEMNLLFQFFnQIVSHKKYMHELLQSEDSDAFIKNLY--- ->tr|N9VZS9|N9VZS9_9CLOT Uncharacterized protein OS=Hungatella hathewayi 12489931 GN=HMPREF1093_02380 PE=4 SV=1 ----FNTQCIKIFAKDagsadwngkAPFEIVIETLSRKFKEQDKIEtvEEYVDDVLSREVNYPTVIGESVMIPHPLM---TFAKETAVAAAILKPPVTICKK---AVKVIFLLAIEGrpNDDVSILFEFFkQVAMNENLVHTLYEAKDETDFLNRLI--- ->tr|A0A1V5MXF4|A0A1V5MXF4_9BACT Inner membrane protein YbaL OS=Planctomycetes bacterium ADurb.Bin412 GN=ybaL_2 PE=3 SV=1 ---QLAPHQIILRLKARSKEEAIRELVAAAVNSsGAEKrEMITKAVLEREQIESTGIGDGMAIPHARTE---AVEGIGICLGTSLKGIDYNAVDGKPVHILLLLVANESahdLYVHTLSSIASIFTDGPFRRDIIRSVDPPQVLARIKER- ->tr|A0A0W0AV70|A0A0W0AV70_AERSA PTS fructose transporter subunit IIA OS=Aeromonas salmonicida GN=VO69_19785 PE=4 SV=1 ---------------SLDKSLALRMLVDLLPAELVRdRPALEQAIAKREQIAATIIRPGLAMPHVICP---AIRQPALSLLSCAEPIEWGSALG-PVRIIILLAIPAglaPEQLRPLTRLARAMMDEVVSTALLHASSAPARQAIVI--- ->tr|A0A0D8R7V7|A0A0D8R7V7_PHOAN PTS fructose transporter subunit IIA OS=Photobacterium angustum GN=UA32_07720 PE=4 SV=1 ---------------DNNKAQLLATMTRSLVDEKvikVDdYQEVLAAIEKRESISATVMGNGIAMPHVMID---PIIQPAMV-ISCCQKMDWHSARG-NVSKVLMMVLPKplsRSVLMAFSRFSKQLLQDHYADALRQASDSNVIQALII--- ->tr|C9P8M0|C9P8M0_VIBME Putative PTS system nitrogen regulatory IIA component OS=Vibrio metschnikovii CIP 69.14 GN=VIB_002864 PE=4 SV=1 ---------------EfANQKDCL-HYI-----AQqanSAdEPALIRQLLAREAIAATTLPPSIALPHVISE---HISTPCLCVLTLAQAINWGSTQA-ETRFIIGLILPKrnpikKEEIMAATRLTRWLIESHHQQLLFQQPNEAHLKGLLL--- ->tr|I0IH15|I0IH15_PHYMF Putative transporter OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_23940 PE=4 SV=1 ------TRATVLEAPEGAgYHGLIELASEVLAKKLPRtASFITEKFVESGNFGFAPMAYGAVLPHFRSA---DIEKPELVMIRSAKGFVTSFkadappgdagsdakkVG-STIHAMFLLVSPEahpGVHLRILAHLAGRLEKEDFMPAWLEADGEQTLKEILL--- ->tr|Q2S0A2|Q2S0A2_SALRD Cationic amino acid transporter OS=Salinibacter ruber (strain DSM 13855 / M31) GN=cat5 PE=4 SV=1 ------AESDVIHLDEPVpYADVVEDVSGRLAEELGLsTETLEHGFLEGAPYSAVSVSHGAALPYCRLD---GISESKMVMVHCQSGICVDLedeieeldRS-EPVYAFFFLVSPKddeGEHLRTLATLANRTDEEQFLVEWRAAADEQEVKESLL--- ->tr|A0A0E9LRT7|A0A0E9LRT7_9BACT Uncharacterized protein OS=Geofilum rubicundum JCM 15548 GN=JCM15548_1390 PE=4 SV=1 ------INARIVNLERKInFEALVEEVSEVFSTEMHVdKDVLVKEFYATSPIEPALVIPGVSILYAKND---GVDHPSLQIIICKNGIRKPVskgaisSE-DYIKVFFFLVNSSeesRQQLRMLSRLIDIVERDEFLEEMLRITSHREMKEFLL--- ->tr|A0A0D3LDN1|A0A0D3LDN1_9BACT Cationic amino acid transporter OS=Flammeovirgaceae bacterium 311 GN=D770_09315 PE=4 SV=1 ------ERAIVLDRKGEeEdYEEVVQQAADALADHLGGdRHTIAEHLHDELKRWLKPQTSEVAIAPVLLE---GIEQPEMVIIRGKITVD----G-KSLNGLVALVDDEdssSRLVSLLSQLEAVVFQSGFVKDWKEAENAEELKAALK--- ->tr|Q1K1W9|Q1K1W9_DESAC Amino acid permease-associated region OS=Desulfuromonas acetoxidans DSM 684 GN=Dace_2765 PE=4 SV=1 ------LRSQVIDLEEECsFEAALTIAAHKLEKVIPLtSDEIVEQIMVGTRIGATPVTRGVALPHFRST---AISQSEMVLMRARNGVRMARynpqtleeeGS-QRVKALFFLVSPDsnpSQHLRILARIAERVDEESFADQWLGAQQRNALKEALL--- ->tr|A0A120GBX0|A0A120GBX0_9SPHN Uncharacterized protein OS=Erythrobacter sp. AP23 GN=ASS64_10405 PE=4 SV=1 ------GRAAFVDYGEGrFdSARLSRELSEIAQNEFGLdEKVAQ-SIFEGDRMDVRAIRPNMYLAYKIIP---DIDESQLAIFRFSGSATVAVtGA-RKVHTLMYLLLPEepvGLDLRIVGHLAEVAQSDNFEERWLAATQREEINRILA--- ->tr|V5WEE0|V5WEE0_9SPIO Uncharacterized protein OS=Salinispira pacifica GN=L21SP2_0753 PE=4 SV=1 ------AEALTVDIDYReSVHGAFQMAGSRLAPKTGMtSEEITRLLEERESRFTTALTDFVSIPHILIP---GRDEIHLVLLRDREGLYFDDSH-PSIHAMFIIVGSEdrrDDHLKLIAGLAHVIQHKNFQDIWLSAESMNDLKDQLI--- ->tr|D0LSU2|D0LSU2_HALO1 Amino acid permease-associated region OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_4824 PE=4 SV=1 ------AGAPLVHFAESAsFEQAARQAAEALADITELpTAELCEGFCTGSRTGATPVAHGVALPHLRIP---DLVRPVMVVVRAPEGVRIDIeditgvRQ-ETAHALFFLVSPTsdpAQHLRLLAAIASVADDDDFKAGFLAAKDGHGIRALLG--- ->tr|E3HB76|E3HB76_ILYPC Amino acid permease-associated region OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_0439 PE=4 SV=1 ------KNAKILDLKGPvTLDELFDIEARHLTSVVDKpEHELIKLFNDREREFSTAITDFTAIPHIVVD---EKDLFYLMVVRCREGIRFNEKR-NSVKAVFLFISSPtlrKTHLRTLASIASLTREESYERKWMSAKNENYLRDMIL--- ->tr|A0A0D2J7S4|A0A0D2J7S4_9DELT Amino acid transporter OS=Dethiosulfatarculus sandiegensis GN=X474_09890 PE=4 SV=1 ------RQGIILDIKEAtKPEALFTLLGKELAVHHLFnQETAANLLASREEKGSTVLLQGVAISDIPHP---DPDQIVLLAARLEPGVVLQKNQ-EQTRAFFLIVLGKnktNEYLQALAALAQITHHFDFMPNWLAGRDSDRLRDVLL--- ->tr|A0A0J7HLD9|A0A0J7HLD9_9BACT Amino acid permease OS=Chitinispirillum alkaliphilum GN=CHISP_3581 PE=4 SV=1 ------INSAVIDLSSHhPgkitPALLEKVVPDCIANITGTePRSVKKHLFKMEQSRITAMEKVVI--LESTL---HVQDSHLLLVRFPSGFEADPqkypflcsCS-KPISALLVVVSKRqqmKKHLRIVGELLRRSDNSEFVAKWVTVPESDRLRELLL--- ->tr|A0A151EVM4|A0A151EVM4_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SG8-52-3 GN=AYK22_07150 PE=4 SV=1 ------KGCDVIDIYKYlPPDKLSIVIAEKLSKRMNLsEKKLYRLLIKREKDSNIVVHPGIAVISHMIK---GRDKFEIIIIRSKKGFILSDNI-DPIHAFFIIIASTdkkSLYLHTLMWIIQIAEEADFGEEWINAKNEEELRDIFL--- ->tr|S7TGJ5|S7TGJ5_9DELT Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Desulfovibrio alkalitolerans DSM 16529 GN=dsat_1824 PE= ------ERALVLDVTGGmDTNEMFSFVAERVEDVHGIsRHEVLRQLTVCCEDGIDVIVPEVAVAHVDVS---ErEGFLEMVAVRNVDGVHFPDG---RVMAFFLVLSSEderRFYIQAVAALAQIIADVEFEGKWRRAKNETSLRHLLL--- ->tr|A0A0D2GHU7|A0A0D2GHU7_9DELT Uncharacterized protein OS=Dethiosulfatarculus sandiegensis GN=X474_09895 PE=4 SV=1 ------RGSKVLEFKKIsDTNQILASISLEAATEFGIeAQELALALKKRQKSQSTEMFPGVAITDALLP---GEGRLELVLVRLAPPVSLSPAQ-SPTRALFVILFTHdrrDAYLRSLAAIAQAAGNESFSRKWDQPKDPERLREILL--- ->tr|A0A101I350|A0A101I350_9BACT Amino acid permease-associated region OS=candidate division TA06 bacterium 34_109 GN=XE03_0756 PE=4 SV=1 ------ENSKTFDIKGKyHFEDLFDLISSTTSSILGIeKEKIKENLLIREKESPTTLSNFVAIPHLLLE---GKGKFEIFFFRVKEGAVFPNE--EGIKMVVVIACTRderNFHLKSLAAIAQMVSSKKFEKEWLQARNENELKEVIL--- ->tr|U1Q4E6|U1Q4E6_9EURY Amino acid transporter OS=Halonotius sp. J07HN6 GN=J07HN6_02933 PE=4 SV=1 ------AFPKQIDADRER--SLVSLAADIVRPD---dGRVIAVRFEEVPD--QAPLTDGLTdqssadrSFETRIE---GLE----------NAVGVDIeadeivSH-DTKHAIINFADKRa-VDTILAEHEPFVFGHGSWVIR-----------STGL--- ->tr|A0A1B6YAG8|A0A1B6YAG8_9BACT Amino acid transporter OS=Balneola sp. EhC07 GN=A8B79_02335 PE=4 SV=1 ------SRSVVLDISDSeIsYRDIIKKASGNFATSFNMdEKQIFDLFWESQDIDTIPFAPSIAFNHIKLK---GDISSEIILARIPDSVFLKSdgfeslsknkqnEI-GNLRAIIFLISSSekpRQHLRILAHLAEIFDDNRFIKRWKKAKNEDEIREILL--- ->tr|A0A1M5DQQ4|A0A1M5DQQ4_9DELT Amino acid transporter OS=Desulfacinum infernum DSM 9756 GN=SAMN02745206_02493 PE=4 SV=1 ------EASHVVDLGRIhGVEELLRELNPALLERGLDrPLGVEDLEGEEPRVKFVEIFEGIGVAEAAAS----rPDVFDVVLVRSRAGISFPGAA-APLHALFFFLVGSdekDFQLKAVAALAQVLQDPKFDSRWRRARNAQALKDLIV--- ->tr|A0A1L8N2F8|A0A1L8N2F8_9SPIO Uncharacterized protein OS=Treponema sp. CETP13 GN=BKP49_03455 PE=4 SV=1 ------KQAKIIDITSShDYSSIIKVAAPDIASELHLsEDEIIEKFQEWYNSCESAVNDFLAIPHIVID---GTDTMFMYIIRSKEGIKFSETY-SSIKAVFLLCGTRddrVRHLKTIAAVASLSEQHEFKKKWLAAENTVCLKNFLV--- ->tr|A0A1L7S313|A0A1L7S313_9ZZZZ Amino acid permease OS=hydrothermal vent metagenome GN=MGWOODY_SVA2440 PE=4 SV=1 ------ARAAVLSVPAGAdIAEAADRAATVLSDRIGLlRDRVTERFLETGSLWIQPSTeHPTATPVALFE---AIDEDHLVIVRAADGIRIPAawggSG-EWVNALFFVAGTAsnpGRSLRVAGELAGHLHTGAWAIG--VAQTEAEVKTALL--- ->tr|G5IIM2|G5IIM2_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_03350 PE=4 SV=1 ---LFKPSLFFTDMEFESREAALSFMCGKLYEEGYVEEGFFESVIKREHIAPTAFEPGFAFSHGME---NNAYRTAVCTCILKNKISWGPY---QVKIVFLFALASsWNHtiIPVYNVMIDHLFQTSTIHKLAKIKDCGEFLDFL---- ->tr|D3AKB0|D3AKB0_9CLOT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Hungatella hathewayi DSM 13479 GN=CLOSTHATH_04053 PE=4 --DLLTADRIQFTDDKLDWREAIRLASAPLIEDGSITQNYVRAMIDSIETtGPYIvLTPGVALPHARPS--KGAKKLAMAMLCSRERIYFNEE--KYANLLIILSSVdGHSHINALVHLSNMFGEEETLEKFMEAQTVEEVVELIHRY- ->tr|A0A174FLI5|A0A174FLI5_9CLOT Putative PRD domain-containing protein/PTS system L-ascorbate family, IIA component OS=Hungatella hathewayi GN=ulaC_2 PE=4 SV=1 --DLLTADRIRFTDFVQDWRDAVRLAAAPLIEDGSITQNYVRAMIDSIETtGPYIiLTPGVALPHARPS--EGAKKLAMSMLCSKERIYFSDE--KYANLIIVLSSVdGHSHINALVHLSNIFGEEETLKQFMEAKNAEEVVELIRQY- ->tr|Q8KEQ6|Q8KEQ6_CHLTE PTS system, IIA component OS=Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) GN=CT0629 PE=4 SV=1 ----------LVELPDNDKSDALQFLATILEAVPSIPagSNIVEIVLEHEKNSNTSLGFGWACPHARVNFD---GDLCCAIGWSPAGIDYGIAGEPLVRLVVMFFVPEnqrNTYLKEVSTLARVLKSNPEFQNLEPIGDLDQVRNTLLD-- ->tr|A0A0P0GJ08|A0A0P0GJ08_9BACT Nitrogen regulatory protein OS=Candidatus Xiphinematobacter sp. Idaho Grape GN=ptsN_2 PE=4 SV=1 ----------LVELASSDKVASLEFLSNLIEAVPNVPpnIDVFRMVMEREVLANTAIGHAIACPHARVRQER--GSLLCTAGWSPVGIDYRAMDSVPVHLVCMYYVPSserGAFLKEMSALSHAVEKDSNMMALLKASSLEEVRGQLLG-- ->tr|A0A1V5ZR89|A0A1V5ZR89_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Candidatus Hydrogenedentes bacterium ADurb.Bin179 G ---FLEPKNILCRMQATCWQDAITELACLLHRNegGFDLNEVVASCIRREEATSTVIAPLLALPHARVK---GLDRVLVAIGTLGAGILFASPDHGPVQVVILILTPHedpGLYLQVLAALTRNLGAPGAPDQLAEYTSADEIYHAFASN- ->tr|A0A1Y4ACH9|A0A1Y4ACH9_9ACTN Uncharacterized protein OS=Collinsella sp. An307 GN=B5F89_06450 PE=4 SV=1 --SLFKPNLVFFGWECATPDEVFDHLAAELEARGLVAPTWREAVGARERVFPTGlktIGCGLALPHADAE---HTLAPFIAIARPATPVPFEPMGGigstVPADIVIALGFNHaDDQIGALQHLMGVFADEERAHAVLAAATPEELVAEL---- ->tr|A0A0N8GMY3|A0A0N8GMY3_9CHLR Uncharacterized protein OS=Ornatilinea apprima GN=ADN00_11530 PE=4 SV=1 --DLLKTSHIVIHDGFDTWQEVVYAACQPLIRDHDIEERYLRATSRIIEEHGafMGLAPGMMLLHAKPT--EGVNQLCISLMKLRQPVIFHNAETGPVDIVAVLGAVdNHSHLTALFQLYSLVQNQAFMADLRAALSPADILRTI---- ->tr|A0A1V4MTC4|A0A1V4MTC4_9BACT Uncharacterized protein OS=Candidatus Aegiribacteria bacterium MLS_C GN=AVO35_07720 PE=4 SV=1 --DALDPGLIEYRTDLSGKEGVLRRIAVLAAGSGKtgaaVEDRIFDALMERESLGSTGFGHGVAIPHCRTGSME---TFMAGLLVSSEGIDFDSIDGERVRIFPFVIGPesePRVYLRLLASIAQIFRHEDTRKAILSLRDPEEVRRLLREQ- ->tr|A0A0A8E4E8|A0A0A8E4E8_9GAMM PTS N-acetyl-D-glucosamine transporter OS=Francisella guangzhouensis GN=SD28_03970 PE=4 SV=1 ---LIDRKNIVLNLNIESKKRLIEFFANRLADAhPEVdEDKVISGIYQRERIGNTYIGKNIYIPHCRVE---GLSTTKIVIATLKNSYYDDTIS-EEIKIAVSVFFPYkisKIHMELLKQLALYLKSPQTQKYFEEADSADTLYKLIVK-- ->tr|A0A109UHJ1|A0A109UHJ1_9FIRM Uncharacterized protein OS=Erysipelothrix larvae GN=AOC36_10320 PE=4 SV=1 ------EELFVYFDERTTKDDILKKLCNITMETNMCDEDLLSALKRRESMGDIVYGNGIALYHPDHL---LSEKTTLSVGVLKYPLEWQKNK--RVRFLFIVCGSKhdEKQLPIlFDKVSSIMRSKEALNQLLKTPDSQTFMNIFEN-- ->tr|F3AR55|F3AR55_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 3_1_46FAA GN=HMPREF1025_00288 PE=4 SV=1 -------KMYLYIDQYMEKIELLNYLCDLCREKRFITEQEAEGIVGRENLVSTEIVEGIAMPHGLIEG-----SSFLVFALLKEPIIWGRT---SVKLVVMGCFQRgDERmKEELEYIFHLFLNLEDKNRLLSCKSAEEIERCMEV-- ->tr|U2U0B9|U2U0B9_9ACTN Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 component OS=Coriobacteriaceae bacterium BV3Ac1 GN=HMPREF1248_050 ----------TPSSEINHYTSVVSRMAKELVDCGLAQSGFHDLVLEREQYASTVYLNGVCIPHPMEP---VGNQDVVSVCVVEHGLTHGSK---EVCLIFLVCLRK-EHINmyqPIaRRLYALMRNRQLVNRLMSVVDGREFIQVFEWA- ->tr|A6DFY2|A6DFY2_9BACT PTS system, fructose-specific enzyme II, BC component OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_18218 PE=4 SV=1 ----LFHDRVLLNVELRTKEDAIKMLCSELMKNGDITdlQATISLVLEREKLSTTGIGDEIAIPHCRSA---DVEYPMavFAYIREGESIDWDSVDGAGVRYIILLVSPlnePQMHIEAMKNITKSLMKPGFIDGLQVAAKRKTTLEWL---- ->tr|A0A212JD17|A0A212JD17_9FIRM Uncharacterized protein OS=uncultured Clostridiales bacterium GN=KL86CLO1_10873 PE=4 SV=1 ----IMEKQILLDFEAKSWQEAIRMSGELLKRGGYVNQNYIDKMVELVeENGPYIlFMPGFALAHASPD--DGASKLGVSLVRLKRPILFEGSD-IPIKYVVCLSITDkDSHISLMYQIYKSLTYEELFDNLSKCSTQTQIIELLRA-- ->tr|E2SHI6|E2SHI6_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_00435 PE=4 SV=1 ----LDPRLSMFQIRAADKNSLLHMLCESLIREGYGNQYIYESLLRREEVSGTAIGNLIAIPHPFPE---DILKSGIGIAVLKKPVLWDDE---KVQIVFLLCISTAenKNLeIIMEDIFEIAQNTELVMELKNTKDLPAFIQSIEK-- ->tr|A0A0C5VE93|A0A0C5VE93_9GAMM Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Gynuella sunshinyii YC6258 GN=YC6258_05592 PE=4 S --NLITKEMVLLDIEAPTKQELIHHLCGQLFLVKRTdsPALLYQDVISREEKVSTFAGASMAIPHALS---HYISEPSLCFARVKSdEFTWDGAD-EAVRFVFMHVVPVQsSdlqrlresQSKVFSAIAELITLTDVQSMWAQTGDKDEILSSL---- ->tr|V5RLA3|V5RLA3_SPIAP PTS system fructose-specific IIA component OS=Spiroplasma apis B31 GN=fruB1 PE=4 SV=1 ---IINTEYIFLNIDIKSKEELFSHISNNAYKWEIVKsiPELIESFKERETLSSTALGGGFAIPHARNP---KIAKPAVFVYRFTKPIVWDDEN--EVEVAIVLLVPEgtGTYLDILSGIATKLMSEKNKDFLKNCQNKTEITSFLIS-- ->tr|B9Y2S2|B9Y2S2_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00097 PE=4 SV=1 -------PELYLEISASSRQEALMKQIEHIQKSLPLPADFYDSVAARERMGTTEYNNKIAIPHPLNP--E-QLPNFISICKLKKPVTWNA---KPVQIIFLVCINENqaLTRIFFDKISKIIQNSHLAFELLETRNYDEFMAKFS--- ->tr|A0A242DPJ4|A0A242DPJ4_9ENTE Uncharacterized protein OS=Enterococcus sp. 3C8_DIV0646 GN=A5876_003301 PE=4 SV=1 ---YLKPDFIRRTSEKLTWQQAVKFACHPLLEDQMITELFIQDCLDQIeeQGYAGYLGSQTCIPHTAPQ--NGVLKDGISLLIAAEPIAFPNG--KKIHFIYPLSFYDlTKHLKAVNQLADISNDSTFLNRLKESSDTKTAYQLIRQ-- ->tr|A0A1F7RXN0|A0A1F7RXN0_9BACT Uncharacterized protein OS=Candidatus Schekmanbacteria bacterium RBG_13_48_7 GN=A2161_08085 PE=4 SV=1 ------------ELDTVDRIEAIKQLCEKLKThPGMLDyKKFCAEVLKRENLKSTAIGNFLAIPHARSE---SVNQIVLAVGKSSKALNFEIHNGSPINYIVLIGTPMdqvKGYLKLLARIVRMFKNNSDRETLLDSKTSTDIAAIFRA-- ->tr|A0A172Q5N8|A0A172Q5N8_9STRE Uncharacterized protein OS=Streptococcus pantholopis GN=A0O21_01450 PE=4 SV=1 ---------IYLNQNLLSRDDVYQFLAEKINkRTGLTKVNILSKFRLRESKGNIQIAEKVVFPHFIAD----KADNSFMILRLQKPIeEWSETI-SDISLIVAMTAKGDLTlaeKQTFAHFIRRLASKDFLEDLLTLNESN-LRTILNEE- ->tr|F8HEE3|F8HEE3_STRE5 Putative PTS system, EIIA component OS=Streptococcus salivarius (strain 57.I) GN=Ssal_01504 PE=4 SV=1 ---------VYANKEFQNQTEVYDFLAKKISLDKAEQEVIIQRFVNREQIGSIQISEKVIMPHFVAS----GYGNHIFLIRPKIPIsNWSTQI-GDVSIIIVIIFEENVSseiKSRLNNLIKNLMNPEFITLLEKESQNN-LINKLNEL- ->tr|A0A135YYH4|A0A135YYH4_9STRE Uncharacterized protein OS=Streptococcus pasteurianus GN=HMPREF3205_00371 PE=4 SV=1 ---------YVSNQNFNNRQEVYGYLASQIDSQTLSQQEIESKFLEREAMGNIEIAQGVVLPHFTNE----NVQDKIFIVRLSEPIlNWSKGI-AKVNIVIALVINSQTAfkiRPQIQNLIQHLIDEQFIELLMTGSQLE-IKNYLKQ-- ->tr|A0A1L8TEK6|A0A1L8TEK6_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL003649 PE=4 SV=1 ---------MFLNQELTNKAQLQRFIAMFAN--PEEADALIDLLQQREKVGNTMIAEHVILPHLESPK---IKQSQVLLIRLAAPVDLDEET-PEVQLVVTILLKSQESqeiKKQIAQFTRRLADEDFLEALLTVESDTRFNQLLEDN- ->tr|A0A239SXJ7|A0A239SXJ7_9STRE Putative PTS system, EIIA component OS=Streptococcus merionis GN=SAMEA4412692_01440 PE=4 SV=1 ---------FYSGESFPDRDSVYDFLVSKLCETAEGQLLLKDKLYYREEIGSIQIEEQVVLPHLQYE----GPWQGIIILRLKTPIkIWSEGI-DSVKLVICLVISEEMEenaKKKIRSFVRKLSRRDFFQFLLQKEESI-IEAYLEQG- ->tr|A0A239WLU2|A0A239WLU2_STRAI PTS system transporter subunit IIA OS=Streptococcus acidominimus GN=alsA1 PE=4 SV=1 ---------IYLEQPLTDKKSALKFLYDNCNiKDHISHNFFLENLEKREKQGSIEIAEGVILPHFEHEA---LTRTKIIIIRPLESIkNWSSTI-SKVDLVIALLYKAGDSln--EIKMLMKMLAKDSVIESLKNEEIEI-VNQIIRSK- ->tr|I6SA90|I6SA90_ENTHA PTS system, EIIA component OS=Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / ---------YVPPTVFHSRNEVYEWLAQQVDSEMGIkKEQIVQALLEREETGDIQIDEGVLLPHIENQ---LVKATKVIILPLEQRIaNWNPAI-QQVELILAVFLAPQEKietKRQIANFMRLLADEQVIKTLKEGKR------------ ->tr|C7T9J6|C7T9J6_LACRG PTS system transporter subunit IIA OS=Lactobacillus rhamnosus (strain ATCC 53103 / GG) GN=LRHM_0380 PE=4 SV=1 ---------VFTNVNLKTREEVYQFVVKQEFPSDIEnAKKLSRELVDREAQGNIQIAESIVLPHAECN---YIQRSKLLLIKTQRSIdTWSSDI-HDIKVVIVMLLKSDESrnvKMQFVDIMRQLGKDELIEQLLSEDD------------ ->tr|A0A091C344|A0A091C344_9ENTE Uncharacterized protein OS=Tetragenococcus muriaticus 3MR10-3 GN=TMU3MR103_0538 PE=4 SV=1 ---------VYPKKSFSSKDEVLTFLGKESSRLVGIpAMEFKEQLLKREEQGSIEIAPGILLPHFESP---SFTQSKVLLLSLNPEVkGWNSEI-NNVKLVIVILLKAEEErpvKQEIAAFTRKLADDKYLDELMKLGN------------ ->tr|A0A0E9GFD3|A0A0E9GFD3_CHLTH Multiphosphoryl transfer protein 1 OS=Chlamydia trachomatis GN=fryA_1 PE=4 SV=1 ---------QFFQQPFRSRQECYEFLVGQLGE---DeSTQFLHLLEERERLASVEIFPGVVMPHLESN---RLKESQIIILQLQDSIQWLNTT-RDVRLIILLAMKKDEEveiKRQLIAFVHQLADEEFIQALLENQT------------ ->tr|A0A033UEJ8|A0A033UEJ8_STAAU Uncharacterized protein OS=Staphylococcus aureus C0673 GN=V070_02364 PE=4 SV=1 ---------EIKTTN-IMYQDVIEEIGSQLKKdQYIQsESVFIEEVHEREQHGNIEIFPEVILPHIQSE---NILKTKIFLIKNETNLmNWHDR---SLKLIILLNLKPQEDqavLQDIQAFMRKLADEDFVESLL---------------- ->tr|V8BSF0|V8BSF0_9FIRM Uncharacterized protein OS=Ruminococcus lactaris CC59_002D GN=HMPREF1202_02161 PE=4 SV=1 ----LPASHIQLGVECQDWKEIVENMGRWMYEHGYVEKRYVASMIENtEKNGPYIvVLPGFAIPHDGQG--KGSIISGMYLVSLRRPIPFGVEKLDPVEFVCCFSAVDlKVHMKAFFSLISMFRNNTFKRKLRECKTSQDAAHLIEEY- ->tr|A0A0E2UEN6|A0A0E2UEN6_9STRE Transcription antiterminator OS=Streptococcus parauberis GN=SS13_contig00003-0102 PE=4 SV=1 --------------PRETYQDYLKEMAKHLQETQLVDFEFEDRILKREEKQTTQFGNLVAFPHTINH---IDGNIILMLGLLEEPFKGTN---NLVEFIFMLAIPKtiegikeAELLELYDDIFRIAGSDSLKNELRKIDNEESFISFTKDR- ->tr|D4ELP3|D4ELP3_ENTFL HTH domain protein OS=Enterococcus faecalis S613 GN=HMPREF9376_01564 PE=4 SV=1 --------------NTQGYRANIQKMIADLEAEKLVDPQFIERIFTREDQQTTIFESGIAFPHTINQ---ALPTIILSIGVFEESLVTPE---GKVDVILLLGIPEeltatveAELLQLYDRLFTIAGDERLRNELRKQRDVLAVKEWMQRK- ->tr|F2I6T5|F2I6T5_AERUA PRD domain protein OS=Aerococcus urinae (strain ACS-120-V-Col10a) GN=HMPREF9243_0306 PE=4 SV=1 --------------QGESYEDLLRVMTDQVIEETGISSDFQQAIFDREAISDTVFDQGIAMPHTVVD---DFGQIILLIGQVEADIQEKG---RPIDLVFLLGIPSqtnqvmdELLINIYEAIFSVANNQDLKALLKTTHSLEDIQDILQGD- ->tr|A0A133Y3N6|A0A133Y3N6_9LACT PRD domain protein OS=Aerococcus christensenii GN=HMPREF3187_00356 PE=4 SV=1 --------------EVSDYKSCLSIMCQQLYDKGLIAKNFAEKIFQREALSPTIFDNGVAMPHAMNN---HKNKTVLAIGQLHPALKTTA---YSVELIFMLAIPEleqettnEVLVQVYEFIFSAANHLNKRHKLLQTTSSKELLHIIQKG- ->tr|S1NS87|S1NS87_9ENTE Uncharacterized protein OS=Enterococcus columbae DSM 7374 = ATCC 51263 GN=I568_01556 PE=4 SV=1 --------------SKASYEQILASLVQPYVLQGILDADFYVHLLEREKKSSTIYEQKIAFPHTLNS---SSQRVQLIVGIPKEAIQTAQ---GEIDLITLLAIPKeltkvaeDELMKVYGKIFELVSDAEKMQQLEQIQDEQSMWQFIDRK- ->tr|R2RCT9|R2RCT9_9ENTE Uncharacterized protein OS=Enterococcus raffinosus ATCC 49464 GN=UAK_04223 PE=4 SV=1 --------------KQLAYEENLILLLEKLRVQQLIDDSFRDYILTKAQEESAIIDNGIAFPHGINR---QSEEILVTIGIYPDG--RST---EDIELIFMVAIPEnltlaveEELLSFYDTIFVISSSETLREQVKQIQTKEEYRQLLVNG- ->tr|E4KN50|E4KN50_9LACT PRD domain protein OS=Eremococcus coleocola ACS-139-V-Col8 GN=HMPREF9257_0027 PE=4 SV=1 --------------TLDSYQAALSWMIQRFEESVTLDTSYRKTVMNQERLHATIFQNGLAFPHGINK---GTESIQMMLGILSKPILVNE---IEVKGIFMLVIGQeldpkteKDLVDIYDIVFRLANEQDFQTSIESFKGKEDFLHYLIER- ->tr|A0A242CAJ8|A0A242CAJ8_ENTFC Lichenan operon transcriptional antiterminator OS=Enterococcus faecium GN=A5801_001231 PE=4 SV=1 --------------EKKTYQEYLNKLVAPLIRGYYVDEKFEKRILKRESQQSTFVNKEFAFPHTTNQ---LSQHIVLSVGLITDQGLAET---GGNGVIFLFAIPEemtaeveNELFELYDILFELIKM-GIDEFIELAPTQESFLKLIKSK- ->tr|A0A091C8I4|A0A091C8I4_9ENTE Transcriptional antiterminator OS=Tetragenococcus muriaticus 3MR10-3 GN=TMU3MR103_0138 PE=4 SV=1 ----ISKDGLIVEENAVSWHEALEQLSQPLIKQKVIEPRYLTALKQELPEIPPYIvfRHQLALPHTEPE--KGAYGVAISFGVFKQGILSTTE--DPIHFIVLLASNNkEKHIDALLEIMDLAGRDAVLSDLLACKDKDEVWRLLRL-- ->tr|A0A0J1F5D9|A0A0J1F5D9_9BACL Uncharacterized protein OS=Paenibacillus sp. VT-400 GN=EL84_01015 PE=4 SV=1 -----SPDDVFF-LNEDNPIDLLKKLTEL----GD-IQHLYTSIVEREKMSSTNIGNLVAMPHPFDC--GDNKKLRVLVAINKQKMLWGDQ---MAQIIFLFIPPKnqkVNNTKFFEEIYDVFKQTNMTEKLLHITNYDEFLEVWSS-- ->tr|A0A0J1ID34|A0A0J1ID34_BACCI Uncharacterized protein OS=Bacillus circulans GN=ABW02_18830 PE=4 SV=1 -----SENRFIL-LDENNKHDFLLRLTEK----VK-MEYLLDGILTREEMSSTEVGNYVAMPHPIAR--TENEETMIYIAINHKPIPWGKT---NVQLVFLILPSEvdrENHYKVFKQLYQLVKSKDKVQELIQTKDFHSFMEVLHT-- ->tr|A0A1G7A9D2|A0A1G7A9D2_9BACI Transcriptional antiterminator, BglG family OS=Bacillus aryabhattai B8W22 GN=SAMN04487777_10713 PE=4 SV=1 -----SPNDLYF-LDEETQKGLLKTLTNV----GG-VQHLYTSINEREKMSSTNIGNLVAMPHPFDY--GNNEKLRVLVAINKQKILWGDK---MAQIIFLFIPPKnqrVNNTKFFEEIHDVFKQTNMTEKLLNVANYDEFLEVWSS-- ->tr|A0A1L8SPV9|A0A1L8SPV9_9ENTE Uncharacterized protein OS=Enterococcus devriesei GN=RV00_GL000919 PE=4 SV=1 -----VtKIDYFTREKYTNKEKLLRGLLSS----IG-TPEMMESILDREEFSTTDISDGIAIPHPLLT--SNLEKTKIAVAIQEKPLDWGSQ---FVDLIIMIVPGKddqKMTSRIMEEIYHIIKDPELLETAKKATNLEEFNQIIEN-- ->tr|A0A087E9K5|A0A087E9K5_9BIFI Putative phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bifidobacterium tsurumiense GN=BITS_1324 PE=4 ---------------AHTKAELLRKVVQELESRGLVTdsAEIITLLHERENLGSTLLTERLAIPHAQSE---AITKAAIVYVATEDPIaDWQSAS----RFIFTFLPeaPDRGDAYAIRDFFIRLADDDVAEALGE-CDEEQVLELL---- ->tr|A0A0R2FR01|A0A0R2FR01_9LACO Uncharacterized protein OS=Lactobacillus mali GN=IV36_GL002327 PE=4 SV=1 ---------------NTKKKELINDVVDYLLKKNLIYscDEVAKAINYRESLNSTIIAHNLAAPHAKSG---AIRQTILLFIKLKEgeFVtDWTEndksID----RFIFTLIPekCSLNDLQALKNFYIHLSKNNVMQLFCR-GKKDEIRKLL---- ->tr|D0DS12|D0DS12_LACFE Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus fermentum 28-3-CHN GN=HMPREF0513_00451 P ---------------SGTKEGFMDWEANFLAQEGIVGniQSVKQALKEREDAGSTLITEQLALPHFKID---EAKEAAIIFVQSAQPIaEWELgisID----RFLCIVVPdsKNKKDLEQLKNFFVWMASDGILEELSL-GSKEVVQGLI---- ->tr|A0A1S9CGZ6|A0A1S9CGZ6_9FIRM Uncharacterized protein OS=Epulopiscium sp. Nele67-Bin005 GN=ATN36_06420 PE=4 SV=1 --------LFIPNLALSSKDEIIIYLTNLLEKENYVSEDFREGVFQREDLVSTDLEAGIAFPHSLK---NIAYKTSMVIAILTEPIIWNTK---KVKVVCMYANSCndIEQSNLFiKLFMSNIDNYTFVESLKKCKTYKQCQQTLLK-- ->tr|A0A1F5R4S6|A0A1F5R4S6_9BACT Uncharacterized protein OS=Candidatus Edwardsbacteria bacterium GWF2_54_11 GN=A2024_01540 PE=4 SV=1 ---YLKSDLIMLEAEVSDKKQLFEKAVDLAVEKGYVFdrEAFLESLWHREQDSPTTLGQGVAIPHSRSGA--ATDEVVIIYISLKRPIPgYVCDDRQPVKIVLMISAGEniQGYLKVLKLIGQAMGRESVRQQLKQADSPGKVMDVFH--- ->tr|A0A1R1HKQ7|A0A1R1HKQ7_PAEMA Transcriptional antiterminator BglG OS=Paenibacillus macerans GN=BK140_24000 PE=4 SV=1 ----FSEDLFYGALSAGTKQEAIHKMCSRIAETGITPPDFEELCLIRENLGSTAFGNLIALVHPIELC---SAVTKVGVGILKKQIDWAGV---PVKVVFVIAQAKsSEARDLLLLIQEIVHDSPLMIRLCEAESFAGFKRILL--- ->tr|A0A1Q8RET3|A0A1Q8RET3_9STRE Uncharacterized protein OS=Streptococcus sp. 'caviae' GN=BMI76_07885 PE=4 SV=1 ---FLTSDRIELEVEANDWQDSIYKVGEKLIAKGDITEDYLKVVISNIKENGPYvvISQGFAFPHAPFG--DYNRKTSMSLIRLKNMIYFDDEEHdnpqdiatMPVKYVCMLSITDrRKHLRAIFNLFNLLKDKDFREKMDSCQTAQEIHNLIYER- ->tr|A0A1Z1W5G6|A0A1Z1W5G6_9ACTN PTS sugar transporter OS=Streptomyces alboflavus GN=SMD44_01091 PE=4 SV=1 ---LLPVEAIRLDVAAEDWRAAIGAAGELLVATGSSTDAYTAEMIRTVVDSGPYivVAPGFAFAHARPS--PAVLRTGMAWVRLARPVEFGHETNDPVGLVVALAAEDaSAHTEAMASLARLLADPETTEALRVAPTPGAVRAILVG-- ->tr|E2SRN2|E2SRN2_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_03926 PE=4 SV=1 ----FDENLIFLEQSVENKEELLKQICDKLLKNGYVKEPFFSSVMQREREISTEIGSGVAIPHGNA---QYVNDTVIVYAGLQKTIPWGRDE--YVQHVFLPVISasNkNEverSIkNFYRRLIALIEHGEI-RRLLDMRDASEVIAHF---- ->tr|A0A1C6F0L2|A0A1C6F0L2_9FIRM Ascorbate-specific phosphotransferase enzyme IIA component OS=uncultured Eubacterium sp. GN=ulaC_2 PE=4 SV=1 ---LLSKERIELDYPAKDWEDAIRCAGKLLYDTKTVTEQYVEEMVNSVKKHGPYIvvCKGMALPHADCS--KGAIEEAASLVRLKTPIEFGSVYNDPVRYVIGMSIKSAEsINQAIYDMMKIFGDENNMNKFDSLPDEQAVLDMINS-- ->tr|G0EQW7|G0EQW7_BRAIP Putative Phosphotransferase system mannitol/fructose-specific IIA domain protein OS=Brachyspira intermedia (strain ATCC 51140 / ---YINNSYVILDLKADNKEEAISEMLIYSEANGLRiNiAQIIESMYKKEDIISSGLGYGVAFPHVRTN---QVEDNDIIFAVSKKGLNYSALDKKPVHLLTMFLTNknsNEKYLGLLSLFTKISRMSMYPVVLLESKTIEEFKEKLI--- ->tr|D5U9U1|D5U9U1_BRAM5 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Brachyspira murdochii (strain ATCC 51284 / DSM 12563 / 56-150) GN=Bmu ---YIDNSYVILDLKASDKNEAISEMLIYSESKGLRiNiAQTIESMYKKEDIISSGLGYGVAFPHVRTN---EVEDNDIIFAVSKKGLNYFALDKKPVHLLTMFLTNknsNEKYLGLLSLFTKISRMSMYPVILLESKTEEEFKTKMK--- ->tr|C5EW03|C5EW03_9FIRM PRD domain protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_05773 PE=4 SV=1 ------PGLVAFGYSAADKMEAIRLGSDMLKKLGYVTDGFVDSVIKREMAVSTEVGFGFAIPHGSP---KFVRHSGIAVVRLDKTVLWHSGE--AVDTIFLIAACtDkrPqdmDELKGFYKiLAVLLDEEGPRKRFKSLNKAQDICNYINGK- ->tr|D5EHU9|D5EHU9_CORAD Sodium/hydrogen exchanger OS=Coraliomargarita akajimensis (strain DSM 45221 / IAM 15411 / JCM 23193 / KCTC 12865 / 04OKA010-24) -----------MELDCNNILDLYVKLGELASKQieGITAEQIHERLTDQSKVFPAFLGHGIAIPHIYCE---DLNYRVCFLAKLKQGIDIPG-QDEPIDFVFFLVSPRgdsDGHLATLAEIARLCRVDRSRKRIKSISSHEDAIAAVS--- ->tr|B5JJ49|B5JJ49_9BACT Transporter, CPA2 family OS=Verrucomicrobiae bacterium DG1235 GN=VDG1235_1849 PE=4 SV=1 -----------YRLaKLKDLDTIYHKLCDQAVLKdpRLDRPTLIEDLEEMARRRSPIFGDDVSALHLYSP---VLERTLCFLAWLETPVTSRS-GRTQVEFVFLLISPTndsEEPLPLLAQFVHLCHDHDALEAWAAKQETTDPI------- ->tr|A0A1V6G6R9|A0A1V6G6R9_9BACT K(+)/H(+) antiporter NhaP2 OS=Planctomycetes bacterium ADurb.Bin069 GN=nhaP2 PE=4 SV=1 -----------LDVHADSLEDLCGVLAAAAARRcpGISEQELAGDLRQKNHALLPYLGGGVALPHIYDA---AARRRVCIAARLARGLVLPD-AAEPIRLVFFVISPPddpKGHLATLAAISRFCVQERHRRALLEAAGAPAMKAYLR--- ->tr|A0A1Z9H9U2|A0A1Z9H9U2_9BACT Uncharacterized protein OS=Phycisphaera sp. TMED151 GN=CBD11_05060 PE=3 SV=1 -----------GPLQSNGIDGILHELMDRLVAArpDINREEILADLLSREQLNPTFVGDGVCIPHTHAR---GLDERVCVLGIAPEGTSYgP----HKVRLVFLLISPTgdpESHLATLAEIGRTCLDPSIRQALMEAQSGTKALQIIR--- ->tr|A0A1Y0L013|A0A1Y0L013_9MOLU PTS system, fructose-specific IIABC component OS=Spiroplasma clarkii GN=SCLARK_00694 PE=4 SV=1 ---------------TINRDQALKEIANLITDSEVINSNIVDGFIKREEIISTGIGNQIAIPHCQV---AGITDDYLVFLKVKKQIDWNSLDEKPVEYIFGIVTQenSDKHLEIIAFISNLLIDAAVKSKIINVKSQKDFVKLILD-- ->tr|C0QXL6|C0QXL6_BRAHW Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Brachyspira hyodysenteriae (strain ATCC 49526 / W --DKITKEHVFEDLESKDKESLFKVLSEKIAPVASAsADAIFDAFKKREDEYTTNIGNGVAVPHGRIQ---GYGKTDIFVGFLKNEINYDSDSDekSPVKLIFAILSDldnPQDYLLNLSQIFFLVNQKEILDKVMATKSYDELASVLES-- ->tr|A0A1R7II73|A0A1R7II73_CLODI Transcription antiterminator OS=Clostridioides difficile GN=mtlA_2 PE=4 SV=1 ------------ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDM---KYIKQSVLCFARLKTPIKIRNG--KDIKIILLLAYKKDDdrkvFRELFKEISNLTEDENMLDILSKCD------------- ->tr|A0A1L8TIS7|A0A1L8TIS7_9ENTE Uncharacterized protein OS=Enterococcus gilvus GN=RV02_GL001501 PE=4 SV=1 ----FDQRLISLEIEGENEEKVFENVAAHLEKLGFVNEGYLNGITARERQFPTGLitqHLNIALPHSDPE---YVDKPFVYIARLKDEVTVKQMGDSqkmGVKNLFFLGIKDpKGQVGLLQAFMELFMKEEFVAAFMQEQEEEKIYQMFVQ-- ->tr|R9J783|R9J783_9FIRM Uncharacterized protein OS=Lachnospiraceae bacterium 28-4 GN=C807_02470 PE=4 SV=1 ----IDPRLFERNHYENSIEQMIQYMAQKIIEMGFAPEEFTASVLEREAITHTSFDNKVAIPHSIVC---STEKNISFIIINEKPMKWGLFD---VQLIMMIGVNHNqrkDFKYIYSNLLERFEDQNIVKRLLNSRNYHEFIEILI--- ->tr|A0A1V6GDH7|A0A1V6GDH7_9BACT High-affinity Na(+)/H(+) antiporter NhaS3 OS=Verrucomicrobia bacterium ADurb.Bin070 GN=nhaS3_2 PE=4 SV=1 ---RLPADRIIARLRATTKEAAIAELIDLLHAQGGIRDraEASRAVLDREHAMSTGLGHGIATPHGRTD---AVDHVVCALGVSRPGLDFGGMDNRPVNLVLLTLFPasqNGRYVSFLAAALATLNDPALMSELVQCETPGAIHDVLMR-- ->tr|G5K553|G5K553_9STRE Phosphoenolpyruvate-dependent sugar PTS family porter, EIIA 2 OS=Streptococcus ictaluri 707-05 GN=STRIC_1941 PE=4 SV=1 ----LVDDNLYLRQQLLDKEAAISFLVEQGSTVNNASPRYLASIIAREAMGSTSVCTGVALPHAAPE---HVSQSQLMLMSLEEPILWGTN---WVSLIILIAIKEgeeERYKDALIYLYSKIDDRDFIDTLAKMEDEDLFMKTLFE-- ->tr|A0A1F9ZQC0|A0A1F9ZQC0_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_10345 PE=4 SV=1 ----------YPSIRVKKSEECIRYLCGRLKEGSFVDDAFEASVLERESLIPTSIQTGVALPHATI---VHALKTSVAIATLQEAIEWGNQK---VSVVLLFAIAkeDIHYLNYFyAIISRFAMDEANIQRLAKCATFDAVIALLYE-- ->tr|A0A1G2Z853|A0A1G2Z853_9BACT Uncharacterized protein OS=Planctomycetes bacterium RBG_13_60_9 GN=A2Y76_01215 PE=4 SV=1 ---LFSPAGVICQTQETERDKILLDMLRLLADRRSIgDvEDAFDAVLARENDLPTIVAPGMAMPHARLE---ALDQIVVAVATSQEGVVYDPNRPdTRVKLIVLTLAPkaaPGAYLQAIGCLARICQDPATADLVASLRTPEQVWAFFDK-- ->tr|C0CWF4|C0CWF4_9FIRM HTH domain protein OS=[Clostridium asparagiforme] DSM 15981 GN=CLOSTASPAR_01320 PE=4 SV=1 ----FHKELYFRNVAQDSAQAYIKFMGGHCLEHGYVKEAFIQDVLLRESVSSTAFTDTLAVPHAIS---QFAEQSFICVVHNNMPIRWNHK---AIHFILLVGITQEemkYFKSSFDLIIELFNSTSRTIELLKTNTFEEFCGRM---- ->tr|U1Y1B4|U1Y1B4_9ACTN PRD domain protein OS=Atopobium sp. oral taxon 810 str. F0209 GN=HMPREF9069_00538 PE=4 SV=1 ----MSPELYLRNLHVSSATd-CIQRLGDHCIAEGVATPELIDDILTREHLSNTAFTDLLAVPHPIT---VSAQRSFACMLHNDEPIPWNgSR---KVNFVVMIGMTKGdtpFFQDILDLVIDLFLSPEKSQAALRTDSYEEFVRIL---- ->tr|A0A242JN64|A0A242JN64_ENTFC BglG family transcriptional antiterminator OS=Enterococcus faecium GN=A5839_001450 PE=4 SV=1 ---------IFPQLEWTDPVDILNFMGNVLVEHHYVEPEFVDSVLERDRHASTRVAPFVTIPHGNP---LYVKHSMISIATMKEPVLWHGE---QIRIVLLLAIKRKdlKHaefKKIFSVIHYLEKQPEQMAQLMQSNHPLEILTLLSSY- ->tr|A0A1U9YPI1|A0A1U9YPI1_9BACL Uncharacterized protein OS=Paenibacillus larvae subsp. pulvifaciens GN=B5S25_12745 PE=4 SV=1 ----LDKSMIKIHTEKVHGKYLLVEMAEQLREKGFVKEGYTESMLKREAMSSTSIGGGILLPHGEY---TLVNRSRVLLHKLKYPLTLENE---SIYFVFMLALKSEdlEGLeQLFYELGDIVDDPVFLEKLKAQHTPADLYDC----- ->tr|A8S5N7|A8S5N7_CLOBW Uncharacterized protein OS=Clostridium bolteae (strain ATCC BAA-613 / WAL 16351) GN=CLOBOL_07266 PE=4 SV=1 ---LFKKELFFPHTNFLSREEVIQFLCERMEASNYVDKAFHQEILYHEQVAPSAYR-NVALPHPLTADESLTRVSSIAVAINDHPIPWDTN---QVDFIFLLSLRGedRqLFKDVFTIISSFLQSDSNCRLLKSCDSFDTFVNLII--- ->tr|B9Y3X0|B9Y3X0_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00500 PE=4 SV=1 ---FFHPDLFFACRQFATHTDAIEVMCAAMTAGGYVDEDYRQQIDYHEKLSPSAYG-NIAIPHPLDNKA---KSSAIAVSVNPRPIQWGAN---QVNLVFMLSLMEkdKeQFSNIFDFIVHIMKDEETFRKMMEVTSFEEFTSLLV--- ->tr|G5HDZ6|G5HDZ6_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00808 PE=4 SV=1 ---LLDESLVAVNVHARNCYDAIQLAGDLLKKKGYITQRHIDEMIRIKrKLGGyMVIDKGVALPHLLAP---ELSGPCMSVITLDKPVRFNHADNDPVDLIVMLLSNhNTAHIKVLEELVDLLGDAKKREAIRLSTSAYELLSII---- ->tr|A0A0K8JHQ7|A0A0K8JHQ7_9FIRM Uncharacterized protein OS=Propionispora sp. Iso2/2 GN=P22_2895 PE=4 SV=1 ------ENLFEYFDMETDYLVCIQALTKRLKQENVITdeQKFYESVVQRENLYSTILDGMIAIPHPLES---FSKTTVVSVGILKEAVKYCG---KKVKLILLFAVNTreSEKLKMLfAMLEELLDSQDKLNELTKCTSYEEFMEKME--- ->tr|B0MD50|B0MD50_9FIRM PRD domain protein OS=Anaerostipes caccae DSM 14662 GN=ANACAC_01493 PE=4 SV=1 ---IISPHLIALDLYAGTWKDAVQLGGSLLMQEGLMTQEYIDSIVKNIEINGPYfvFWPHIALAHANASA--EFMPFSASLIRLKQPVFFGNEQNDPVKYIFTFIASDtsENDEKIL-SVINVASSPTLFQHLDEAKTPEEVYGIIHE-- ->tr|A0A1M5BX77|A0A1M5BX77_9CLOT Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Lactonifactor longoviformis DSM 17459 GN=SAMN02745158_03860 PE=4 SV=1 ---ILPEKNIILESGCRSKDEVIAYAAELVLGdcSGRAKEKLKQEIWERERLAYTGIGSHIALVHAESV---TVDCPVTACIRLKKYIDWAPGKAypplhKMVKLVFVFAVPKEegPETEVLKDMVRKLGKKETVDRLMRAEQSREIIGIF---- ->tr|A0A1T4LVV3|A0A1T4LVV3_9ACTN Transcriptional antiterminator OS=Coriobacteriaceae bacterium KH1P3 GN=SAMN06298223_0830 PE=4 SV=1 ---FISADDVQIASSSSGWEAAIGKAARPLVSRGSLEQRYVQRMVRAVKEYGTYmvMTPGTAYVHAGTN--DGINEDCTALLHLRSPVIFGDENAKPVRDVVVIGVKSSES-KALISIAKILSKETNRRRLEES-------------- ->tr|A0A1Y3SKR5|A0A1Y3SKR5_9FIRM Uncharacterized protein OS=Pseudoflavonifractor sp. An85 GN=B5G37_06605 PE=4 SV=1 ---YILPENIQILDHCSSWNDAIKIASAPLLQRGDIEQRYVDQMINAVNNYGTYmvLTPEVTYVHAGVN--DGIQRNCAAMLLLRTPILFGNFDRKRIRAVVVLGINNRQEDSELINLAYILGNEDNLQRLKDQ-------------- ->tr|A0A0T8I7K7|A0A0T8I7K7_STREE PTS system transporter subunit IIA OS=Streptococcus pneumoniae GN=ERS021354_07329 PE=4 SV=1 --------MLAvlktaYQLKHakggrkpklsleDLLMATLQYVREXLEEREIVTPTYREALITREKSFPTGLDmeflgkdlPNVAIPHTDIV---HNLAEKVVVVRLEKPVTFHNMIApdKevEVSLLFFIINNsSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAE-- ->tr|A0A0R1F5Q6|A0A0R1F5Q6_9LACO LicABCH operon regulator OS=Lactobacillus coryniformis subsp. coryniformis KCTC 3167 = DSM 20001 GN=FD22_GL002407 PE=4 SV=1 ----VLKNSVLVHGQFSNKTEVIKQLLVQLKQ-----PEMLDNVMERERLSSTDVGTFTALPHPLIM--KTDCPFSMGIAVLDKPIQWGER---EVSLVILPLPNSNNHLEYERVfgiLQKIIVNEDNLAQLKRLQVPTDFMKLI---- ->tr|A0A1U3S5U3|A0A1U3S5U3_9MYCO Probable licABCH operon regulator OS=Mycobacterium abscessus subsp. massiliense GN=licR PE=4 SV=1 ----LSKDDILSkiqlsvEsnfklnhsnhilPIFEKSKEILDYH--HATL-----DGYIESAIDREKQSSTYIGKGIALPHGNPE--KVL-KSHMIIFKPSQPITWKQH---EVKLVFFLAMSKK-DLNINRKiIQSIAqLEEDDIHQLcllDDLQLKNTLYARF---- ->tr|A0A089XY57|A0A089XY57_9LACO Putative galactitol operon regulator (Transcriptional antiterminator), BglG family / PTS system, mannitol/fructose-specific IIA ----KPYIKVIFTHQQYSWTRLIAKISEPMIKSKIVNDAFFLALKKEYCDQPDYIllNRQIPLLHLDPD--VYPQQLGLTLLVSANPVKYGSA---KVNVVALLTTPNkTDHLPLLYQVKNMAKDTTFIHTLSQSANTKEAEKLVQK-- ->tr|A0A0E9E4S8|A0A0E9E4S8_CHLTH Probable licABCH operon regulator OS=Chlamydia trachomatis GN=licR_2 PE=4 SV=1 ----IKNENIVLAEDRLSWESILNQSSQALVNQKIISSDYNELLLQEYLDQPSYImlRQRILLPHLDPA--IVDQKLGVFITVLKQEITYHGK---KIHVVALLTTPDkTSHLPILYHINRMANDAEFIEELVKLEDVNEISKAIRN-- ->tr|F3L6J4|F3L6J4_STRPO PRD domain protein OS=Streptococcus porcinus str. Jelinkova 176 GN=STRPO_1597 PE=4 SV=1 ----LEESSIQIIDYRINWNDALKLVCHPLILDKKITDDYARALQEEYKEKPIHImlKSKLLLPHLDPY--IYQQKLGFSLLVLKDGILYNDQ---MIHFILLMTTPDkTSHLPFLLELRDLVAKENFSDLLLEANSADDIIKQIKY-- ->tr|A0A0R1NCD0|A0A0R1NCD0_9LACO Uncharacterized protein OS=Lactobacillus perolens DSM 12744 GN=FD09_GL000280 PE=4 SV=1 ----LPESLIFREQYFNGAQSCITWLCEQMNHQGYVSTTFKDDVLKREALSSTAFVKDIAVPHPLKPV---TAHTTIAFVLNHKPMQWGDS---YVRIIVLLGLSPNDHdefQVIFDALIAALSNADTVQKLLDTQSYTEIIDILRDS- ->tr|A0A1G1BBY7|A0A1G1BBY7_9BACT Uncharacterized protein OS=Melioribacter sp. GWF2_38_21 GN=A2X65_03855 PE=4 SV=1 ----LDKDSFHYSCEL-AESSYIAQMISQIRFEKNVDsEIIVQLLKSRESMMSTAIGNGISLPHPRVPLMVGRNKPLINFFFPIKQLDLKSIDGKPVHTIILLISQTiKQHLSLIAHLSFLLSNQAFRFALENRLDSREILDIIKK-- ->tr|A0A1W9RYS6|A0A1W9RYS6_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium 4484_93 GN=B6D65_02580 PE=4 SV=1 ---LISRNVVLLGFSAGDKESAIRVLVDELTEQESLPdpRGALSALLEREKN-MTTGTEEVAFPHARLDSL---SDLYLLFAISPDGVDWGAIDRKKVHFIYLVLAPPsknSLMINLNAAFSELLSAKDARKILLSAKAPADVVDYIDS-- ->tr|A0A1V5FN42|A0A1V5FN42_9BACT PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=candidate division BRC1 bacterium ADurb.BinA292 GN= ---LLNENHVLIGEAVQTMEEALRRMVRAFGAAVAPDqvDPLVHSLLAReEQH-PTVIDDRVCIPHMRMESL---DVFLLGLLVPEHPIPHPNPEQGPVALIFMILAPQtknTMMLQTLAAIARLLKSRETKQAILSVRSAPRLLRWIED-- ->tr|A0A177Q2L6|A0A177Q2L6_9PLAN Uncharacterized protein (Fragment) OS=Planctomycetaceae bacterium SCGC AG-212-D15 GN=AYO40_04405 PE=4 SV=1 -----LPEAILPDLRARSKAEAIRAMVESLGHALALSaeqiAATVTALLRREELGSTGMGRGVAVPHCSVP---FVAELVGGLALSREGVPFDSVDGRPAHFLVLMLAPAdrpGPRLKALERISQSLRQPrTYQGDLFRCRTVEEILAYAK--- ->tr|A0A1F8JM20|A0A1F8JM20_9BACT Uncharacterized protein OS=Chlamydiae bacterium RIFCSPHIGHO2_12_FULL_49_11 GN=A3F09_05690 PE=4 SV=1 ----LPPEQIFFFD-HGDRMEVIEKLCKGLLPEKLI-PAARSKILEREGEASTAIGKKVALPHASIDALDD---FILGVAVSpHAPItGWETFDMEPLHIVVMILAPSgrrESYLEILSEISKKLGQRRVVDEILKARTREEVAKIFH--- ->tr|B1ZSD8|B1ZSD8_OPITP Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1) GN=Oter_2455 ----LRIGGIWRDVPAGSVRDVLSRVVEKLPGaTPTVRQFLAQRVQAPGGITWAAVGHGLALPHLRSHVALGREAGLLAMLFLRDPVSLDgeeAPDGVPVnRLLFFVAPTPRAHLELLAHLSAALSRGSLRQLVRDAAGDQEIFAAVAA-- ->tr|W0J5V3|W0J5V3_9BACT PTS sugar transporter subunit IIA OS=Opitutaceae bacterium TAV5 GN=OPIT5_19310 PE=4 SV=1 ----LRAGGIWRDVSADGLTGVLDQVVATLPGaTDPIRRLIVQRLHTRGGITFAPIGDGLAMPHPSARVALGRDSGTLALLLLREPLALSeeAPDGVPItRLFFFIAPSPRAHLDFLGKLCRLLGRGPLRAAVLRGAEDAEIHATLAE-- ->tr|A0A1G3ZGH0|A0A1G3ZGH0_9BACT PTS sugar transporter subunit IIA OS=Verrucomicrobia bacterium GWF2_62_7 GN=A2107_07520 PE=4 SV=1 ----LRAGGIWRDVPSSGAIEVLERVIASLSSiPQPVRALLAQRLRAKGGVNWAPIGGGFALPHFSTRVTLGRDAGVITLLLLRDALTLTepPSDGVPVtRLFFFIPPSPRAHLDTLARLSRAIAHGPLLGLVERSAPDEELFQTLAA-- ->tr|A0A1M6GML9|A0A1M6GML9_9DELT PTS IIA-like nitrogen-regulatory protein PtsN OS=Desulfatibacillum alkenivorans DSM 16219 GN=SAMN02745216_01050 PE=4 SV=1 ----MRRGGVFKDVEGGTVDEALTQAASL-SPvAGDHLQAFTQQLLERERLCSTGQGKGVAIPHVRSQTEDAGAEASVTTCFLKEPLDFNAIDGKPVtTLFLLISPSVDVHLRLLSRLAFCLRDDSFVEFLNQRPTSDDLLGKVQE-- ->tr|A0A0E2EKS0|A0A0E2EKS0_STRMG Putative transcriptional regulator OS=Streptococcus mutans 2ST1 GN=SMU29_02201 PE=4 SV=1 ----FSKDAFLQL-SDVSKEEVLKKMILSISKGekSHFADKMEELIYQRETMSSVVFSDTIAVPHPIKAV---GNRHHIAVAMIKDGLFWNQDY-PKMKLVFLTSMSiyDNDGLPELaSCIATLVDRPDIQQKMLTCQSFEQFKKLFLK-- ->tr|C2BGB6|C2BGB6_9FIRM PTS system, Lactose/Cellobiose specific IIB subunit OS=Anaerococcus lactolyticus ATCC 51172 GN=HMPREF0072_1386 PE=4 SV=1 ----FSEKNFLINKnP-CTKDEVLNLIYKSLAL-tPEMEEIFRDQTLLRENFGSIVFKTLVAIPHPISPI---KDKAEIFTVISKADISWGKDS-DKLKIVFYISPPgkNDPDFEKIiKVFTKILKDDSLIQALINIENFIDFKELILN-- ->tr|S0J0C7|S0J0C7_9ENTE Uncharacterized protein OS=Enterococcus saccharolyticus subsp. saccharolyticus ATCC 43076 GN=OMQ_02559 PE=4 SV=1 ----FAPELFLYLPGKSVKEQVIKELVARVEKIegSPLSERLMKQLQLRDTYSSVAFSSSLAVPHPIEPV---TQNAHVAVAIAPEGIFWDDEH-PAVQLVFLSLPDkaRQVQIDKInQMFVPILEDKEFGDSLVASQSFDEFMKKFVS-- ->tr|A0A175CQ94|A0A175CQ94_LEUGE Transcriptional antiterminator of lichenan operon, BglG family OS=Leuconostoc gelidum subsp. gasicomitatum GN=PB1A_1596 PE=4 SV ----TDSSRFKIWDeP-TYRKDVLDQLSDMITTDepSDFKQELLDQIAHRELLSAITFSDVIAVPHPARAM---SRVPKIAIGVIPSGLKWSTDY-PSIKLVFLLSPSylNNQGLTETtQTIVYLAENPEKQAELILAKDFSEFRKKFML-- ->tr|A0A011SIB4|A0A011SIB4_9LACT Transcriptional antiterminator of lichenan operon, BglG family OS=Alkalibacterium sp. AK22 GN=ADIAL_0783 PE=4 SV=1 ----FSPELFEVSDTVMDREEAVEVLIEKCTRVdeQIDADFLNRQLRLREGFSSVVFTKHIAVPHPVEGV---GDFSKVAVLVTPNGINWDGVS-EQVQLTILMVPDrfGHSHLDQVsKALLPVLENESYLEELIQAKDYPTFKETLLS-- ->tr|C0MDB9|C0MDB9_STRS7 Putative regulatory protein OS=Streptococcus equi subsp. zooepidemicus (strain H70) GN=SZO_06860 PE=4 SV=1 ----FSPKRFLYVKeK-LSKKALLLKMIACLDEAmdEAFVEAFYHQIVLRENYSSIVFGEVLAFPHPANPM---TYSEQVVVAVCQEPIDWDESH-RAVHFIFLLSPSkgRNSYLKYIsLSLVSFVNQAELQQALLEEPSYVQFVTLFTP-- ->tr|A0A160JSD9|A0A160JSD9_STRSU Transcription antiterminator BglG OS=Streptococcus suis GN=A6M16_09980 PE=4 SV=1 ----FAPHRIIYLEeG-CDREVALKQLVTTLNESiePDFVNRFIEQVNLRESYSPVVFGDRLAFPHPALPM---SYSEQIVVGIYKNAVDWGHGK--QVQFVFLLSPSkgRNAFLKYIsPCLVDFVQDRVLQERLLHHPNYKELIDIFIP-- ->tr|A0A178NVG3|A0A178NVG3_STALE Uncharacterized protein OS=Staphylococcus lentus GN=AXY34_05090 PE=4 SV=1 ----CSDYLFNYIEgS-IDKESIYNRLIQQLSIKedRDFECKLRNQLAYREELSTVLFSEAVAVPHTAQPV---GDYSSIAVAIIPEGIYWNDAY-QNIKVVIMLSPSkyNDNELKTIiDVIVNLIDSEENIQKLMECKTYQMFKDFMIN-- ->tr|A0A147IAR3|A0A147IAR3_STASC Uncharacterized protein OS=Staphylococcus sciuri GN=NS1R_14350 PE=4 SV=1 ----CSEHAFNYIEeA-TTKHQLYQLLIKQLSIKeePCFEEKLKRQLRYREELSTVVFSDEVAVPHTAQPV---GDYSSIAVALVPGGVYWNEQF-PNIKLIIMLSPSkyNDNELKTIiDIIVNLIDSDDKISELMNCKDYNSFKNYMIG-- ->tr|A0A139NCX0|A0A139NCX0_9STRE Transcriptional antiterminator of lichenan operon, BglG family OS=Streptococcus sp. DD10 GN=STRDD10_01410 PE=4 SV=1 ----FSEQHFQIY-HSGDKEVVLENMVQDLLVGdeEIRRDDFLALLAEREAIGTVVFSERIAVPHPCEPL---TRQAQVAVAICKEPLVWEEGR-EKIQLIFLLSPSiyNNEGFKVVtQKILAVTENEKIQEELVACEDFSTFLSLLKK-- ->tr|A0A1E9PP80|A0A1E9PP80_9LACT Uncharacterized protein OS=Aerococcus sp. HMSC062B07 GN=HMPREF2680_02985 PE=4 SV=1 ----FSEDRFIVTHkENINKEKMLSHMIALLEDNpqTNFNEMFLREIKIRETYGPIIFNNILAIPHPTKPL---TKDEKIVVAIIKKGLYWDSEN-PNIRFIFLLSPSitNNKNMRQVsNSLAKIIENKSLEDELLNINNYNDFKNIMLK-- ->tr|A0A1E8GN68|A0A1E8GN68_9LACT Transcription antiterminator BglG OS=Anthococcus sp. DF1 GN=BG261_02725 PE=4 SV=1 ----LSKEMFEIFEgENISKKCILDELLAKASQSerEDYKERMIEQINQRESMGQILFSETVAVPHPVLPV---GMTTKVAIGVIPKGFSWNDEY-ANVKFVFLISPSyiENENLISItKAIVKLVESENLQNDILQDITFEHFRNNFLR-- ->tr|A0A1S8KQE0|A0A1S8KQE0_9LACT Uncharacterized protein OS=Dolosigranulum pigrum GN=BWX42_09775 PE=4 SV=1 ----FRPELFSTKKNISTKEEVISQLVKVAVEYdpSINKTFLEGQLKLRESFGSVLFTKTLAIPHPIEGV---AEESKAAIILTPEGIKWSEDA-SEVLMTILLLPDryGGEDITELsKILTTLIEKPDKIELLSKVESFSEFIDNFKL-- ->tr|A0A242CYF6|A0A242CYF6_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_004465 PE=4 SV=1 ----VSEELFFVANEYADKTMILTEMLRRIEQKeeRVLKETFMKQIKLRESYSSVAFSNYLAVPHPIEPL---TNAAHVAIAIQPEGFYWDQAH-PNIQLVVLLSPDkfGHLNMDVIsQALEPILDNREFQQAILKCTSCQSFMEILKN-- ->tr|R9LTE6|R9LTE6_9FIRM Uncharacterized protein OS=Firmicutes bacterium M10-2 GN=C815_00211 PE=4 SV=1 ----FHPSLFFDHLPPMSRQEVLSVLSNRLWREGFVDETARDSFWQREQLGTTEIGNLLAVPHCMA---GTVVRPAIAVAVLEKPIVWEYG---MVQVVLMIAVSKEflkKENGFFLRLYQRLNTTMKIKEFINTRHLDLLMDAF---- ->tr|A0A1V6CQY0|A0A1V6CQY0_9BACT PTS system mannose-specific EIIBCA component OS=Planctomycetes bacterium ADurb.Bin126 GN=manP_2 PE=4 SV=1 -------RTVAVDLTAESKEQAIEMLVDALVDARQVPlarrDEVIAAVMRRERCGATYIGHGTAIPHAALC---GFRGLVGMLGVFPDGVPFGKAEDEGAKFLFLLLTPKEsyeVYLPILARIARFMNEPDHRRQLTQAATSADVVALLGQ-- ->tr|B9YAP5|B9YAP5_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_02902 PE=4 SV=1 ----FDDQLFFCNHGLTTEVEILTFFDQLLQQRGVIDNQFMDSVRQRESLSSTAFFNRFAVPHSLEK---DALLTKVVYYYSDEPIRWYDS---RVNLVLLILSRSDdeQASKIYNLIFDILIDESCYKKMILCRSRQELMDFLEAN- ->tr|A0A0E3ZC50|A0A0E3ZC50_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_05505 PE=4 SV=1 ----------VHIDKTVTKDEVIRILCNMIKKHTNTTFPIYQKVLEREKLGFTEILNNIAIPHPMTKD---FNFNKVAIAVLDNKIKWDKK---FVNIVLLVCINDfdRYSEIIYSNIFNLFFSKEKLERLQKNPTYSNFMNLLKEG- ->tr|D1AWK7|D1AWK7_STRM9 PTS modulated transcriptional regulator, MtlR family OS=Streptobacillus moniliformis (strain ATCC 14647 / DSM 12112 / NCTC 1065 ----------IYLDEIKNKDEIIKLVSDKLMKIPNMNNDIEALIHKREKLGMTEISNEVAIPHPIGVI---EGVNVIGVCISKNPVKWINN---EVNIILFLCLDNknNKNEKIYEAFTKIVGNKEIINDILLNPTYDNFINILEHI- ->tr|A0A1B3XNV9|A0A1B3XNV9_9BACI Uncharacterized protein OS=Bacillus muralis GN=ABE28_011110 PE=4 SV=1 ----------------------gkFVWLQAIISQSHVviSPEGLIEAFKERERKGSFAIG-PIGILHSRT---SDVRALFVHIISLKEAVPWHAEngQKQSVDTLLLLAAPpdaPREHFPLLGELISGLLDDELAGAISSG-NKELALNA----- ->tr|A0A1M4YKT4|A0A1M4YKT4_9FIRM Transcriptional antiterminator, BglG family OS=Alkalibacter saccharofermentans DSM 14828 GN=SAMN02746064_01796 PE=4 SV=1 -------------------RD-elLKYIARYVSG-QDraRVEKLFEDIKRREDLMGTAIKSkNLALVHAKS---ESVDEVIAGVFRTKSPVAFTDAegNKELVDTVLMLLMGcdtPREHKEMLSQLSAMIVEaEDFIPMLRIG-DEEEIKEV----- ->tr|A0A1Q5P042|A0A1Q5P042_9BACI Uncharacterized protein OS=Domibacillus mangrovi GN=BLL40_14940 PE=4 SV=1 -------------------PVTIPSILNQIKDAQEisDLGKLSKDLEKREQQGGFVIG-DLAMVHAKS---EGVNNLLVVVFRMKELVLWPfADdeEQQSINTVLLLATPkeaPKEHIEMISEISSMLIEESFVSVLKES-TADVVKST----- ->tr|A0A243VZI1|A0A243VZI1_9ACTO Uncharacterized protein OS=Actinomyces sp. CtC 72 GN=BW737_13105 PE=4 SV=1 -----DPELFTRIPGGQDRDAALETAVSLLARAGAVGPEFLDQVKEREQLSTTAFASGAAIPHTIE---MTAARTAIAVCLADRSVDWDG---TPVRLVAMLCLSAdsrDAFGDVFDAVIKALVDPAKVARLAVADSYDAFVATM---- ->tr|A0A1R2E6V8|A0A1R2E6V8_CLODI Uncharacterized protein OS=Clostridioides difficile GN=BER30_002517 PE=4 SV=1 ----LDEDLVIFEPDIYFKKDLLEYVCSILINKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDS---STVNSTRFVFVKLKNPIDWGVG---NVNFIFMPVFQAN-DKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIF--- ->tr|A0A1A9YQS4|A0A1A9YQS4_GLOFF Uncharacterized protein OS=Glossina fuscipes fuscipes PE=4 SV=1 ----FTEATTFLKTAASDKTAVFKTLATALGNSKIVTneEQLIKALEKRETEGPTGVGDGLAIPHCSN--------------------------QKPVDVIFMITTPEkggEQHLQALAHLASFLGKSEVVAKIRAAKSFDDIITAFV--- ->tr|A0A1M5T5U3|A0A1M5T5U3_9FIRM Transcriptional antiterminator OS=Sporanaerobacter acetigenes DSM 13106 GN=SAMN02745180_00381 PE=4 SV=1 ---LFSEERFFTDLKNQDKYDLIDEIGEKLIAQNAIDKNTLNEVIKREHVSSTKIGNLVAIPHCVSS---SQSSSLIAVGLTEEPVVWDDE---KIQMIIFICFSEndTSSIKVFNYLYDLVRDEATIMNIVKNKSYDYLYEILFR-- ->tr|G1VPL8|G1VPL8_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_01949 PE=4 SV=1 -----KKELFFNCVEGKTRQEVIHNICCRMQKHYDKPIGMLEeKILERENLYPTDYGNFIAFPHPMEA---CTEETFISVSVLKDAVKWSEK---RVRIVFVISYGKgyveEEKIKNLNTLtFRLFSNREAVKRILENPVYETVIEQLI--- ->tr|A0A1L8SAJ9|A0A1L8SAJ9_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus GN=RU99_GL001825 PE=4 SV=1 ---MMRPELIQLNKKARTWEEAFYLAANPLIERKIITRNYIDSIIQQTRSEGAYmvIFDQVALPHTVPE--AGAKKLGMGLTTLESEVYVLGT--IPVKYIFTLSALdSKQHLNAMTQFITLIESKDFFRELEKHECPETVYQWFAE-- ->tr|W7BU39|W7BU39_LISGR PTS modulated transcriptional regulator MtlR family protein OS=Listeria grayi FSL F6-1183 GN=LMUR_06729 PE=4 SV=1 -----------FHSDLSTREAILNEFSNKAAALGLCDDDFSASVLKREYRASTSIGRGMAIPHGNS---LSVRENAVFIIKNKRKVSWGVDE---VDTVILLVIhfSEgKKDGEFLGRLYNCMEKTDLIRNATGEESLEKIKKY----- ->tr|U2ILZ3|U2ILZ3_9STRE Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Streptococcus sobrinus W1703 GN=HMPREF1557_01383 PE=4 SV=1 ----LKSNYISVIPGVDTIEDVVKKSAQPLLNDKIITREYLNRVLRNLANhrQNYQIAPGILLPHASPE---GVNQIGLSFVILDKSIDTSYG---KIGLVIFLAAvDNTQHLLVMKDLLKLLSDANFIEEIRSQKSSEDILNLIQT-- ->tr|A0A0R1IEQ1|A0A0R1IEQ1_9LACO PRD domain protein OS=Lactobacillus paralimentarius DSM 13961 = JCM 10707 GN=FC97_GL000087 PE=4 SV=1 -RELLTLRNIKImhVNKNTTWLDVLHTGCRMLSQQEIIEPRYENEIVKLIKKYGPYmlISDDIFMAHASPK--NGSNRVGISMVLLDNPVIIAEKNQkVNVSCMFVLSPGsNHEHDRVLEELISIVRNTEKINKILVSKDKLEIRKLM---- ->tr|A0A087Q9U8|A0A087Q9U8_LACGS Putative PRD domain protein OS=Lactobacillus gasseri SV-16A-US GN=HMPREF5175_01914 PE=4 SV=1 -MDLLNRSSIKIidNLMnGTDLNPIIKELSEELEKNNIVTSGYCDDILSLIDKYGPYmlLSSDTFLAHAAPS--KHTRKIGIEIGILKRPIKISVNNIeEKIKCVIVLVPGfHQEHDKALAQLINIITNRRLYDQILSETDTDKMYKLI---- ->tr|A0A0R2AMB6|A0A0R2AMB6_9LACO Uncharacterized protein OS=Lactobacillus agilis DSM 20509 GN=FC14_GL001451 PE=4 SV=1 -VDLMSQNDIIF--SkESTIQRVIEEGTSVLERKGVVTKDYLSEINRLISQYGNYmhLSNGVFLAHAEPQ--DGVLKTGLSLVISKKGIPLSDG--SVVKLVFVLAPGtSEEHSKALSEIVSIARSKEKVQAIVDIGDRNEIYQYL---- ->tr|A0A1F9VF44|A0A1F9VF44_9BACT Uncharacterized protein OS=Elusimicrobia bacterium RBG_16_66_12 GN=A2V88_03045 PE=4 SV=1 ---------VEANLPTGDRRTAVRHLLAKLKALrpSLDAEGAFTAVWDRELKFASAVGRGVMVPHARL---SGLGEPLIAVGRYAKPAPFPTPDGVAVRLVFLVLSPAEtpiIQLKILQRIASLVTNENIRRKLWRAKTDEALFTLLST-- ->tr|A0A1G3KQX9|A0A1G3KQX9_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWB1_36_13 GN=A2Y41_13700 PE=4 SV=1 ---LIQEDSLIFNLKASTKNEAILEIIQTFSPDKKKNQEIYDAVIERENIGSTlIENTGVVFPHVRSA---ALDDFYIGIGISEKGIETENNLGGMEKafLFLVVAAHplkNQLMLNIRSSLLKLLKTDpALFE---KLKKPAGRDEFLS--- ->tr|A0A1G2ZEK4|A0A1G2ZEK4_9BACT Uncharacterized protein OS=Planctomycetes bacterium RBG_16_43_13 GN=A2W23_06755 PE=4 SV=1 ---LLDTRLIKCGLEAQDKDSALTELVKLLIGydATISEQGILSALADREKLGPFSLGKGIGFPHARTD---SVKDLLIVMGTSQNGIDFRSPDGQKAKviILFIIPKKhSNLYLHAFAAFLNFFSLEvNLLKV-ASAKTPAEVIGYIE--- ->tr|A0A1Q8EAX0|A0A1Q8EAX0_9STRE Uncharacterized protein OS=Streptococcus cuniculi GN=BU202_01220 PE=4 SV=1 -----DETFFYPQLKVETATEAITVMVDKLKRYSIVDDSFLESCLQREACSATSFDYSLAIPHPLVL---NSRQSVISIAHLDHPIEWGGS---RVEMVMLLALNeaDREFMTIfFDWLARIISDQDSIRTLVSIDNRDQFIQYIVQ-- ->tr|A0A0H0YJE9|A0A0H0YJE9_LACCA Transcriptional antiterminator OS=Lactobacillus casei GN=AAW28_13850 PE=4 SV=1 ---LLVPSLFFQQSTPTDYRGLLTTVTATMAE--YCgQADYAASVLQREDFLPTIYDNGIAIPHPLSF---NAKKNAVAVILLPNGATNTA---RSVQLVWLIALKQDqlpLHRTLTMQLAALMQKADVINKLVQQTEFSSFHQILRT-- ->tr|A0A0R1NBK3|A0A0R1NBK3_9LACO Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Lactobacillus rapi DSM 19907 = JCM 15042 GN=FD12_GL001 ------EDSVIFAEKQYTKRELFESVCNQLAKSRVLSdaSEVVKQLLEREEISDTRIDDLIAMPHCES---SAVIFPKIILVNCRKfPIFWDHDV-MVTGIVFLFIPtSDSDEIKEIPHFVKKLADPNVTKELFESNNRTQFI------- ->tr|A0A0R2LQZ5|A0A0R2LQZ5_9LACO Uncharacterized protein OS=Lactobacillus paucivorans GN=IV54_GL000501 PE=4 SV=1 ------GTQAILVKRHLTKQQLFKRVCQALGDQAVITepEVAVAALEERERLAETLITERVAMPHCQS---AVIKQSKVVLVNCKRfPITWDDVGHQVEGLVILLLaKdAPQDQLQRITDFVRQLADSDVADSLFEEEPTAADS------- ->tr|A0A0R1QB96|A0A0R1QB96_9LACO Uncharacterized protein OS=Lactobacillus nagelii DSM 13675 GN=FD45_GL000569 PE=4 SV=1 ----LSEEHFQISRSFADKKSFIEQRGNDLLKTGYIEADFLGDVLKRESMSSTNMLNGVAIPHSLQ---IGANRSIIDITIFPSGVVWDQNA-APVEIVVLSCIKASDqaiFGDFMDHLVKITSNSKLFNRLKESRSFNDFLHELR--- ->tr|A0A1E8VUI2|A0A1E8VUI2_9ACTN Uncharacterized protein OS=Olsenella sp. HMSC062G07 GN=HMPREF2826_04895 PE=4 SV=1 ----LNSDGVRIENGPLRWKDAILLASERLQKGGFVQESYVEKAISNVEEYGSYivVNQGIALAHAGSE--DGVEKDGISLLICPDGIQFDDID-DAVHLMFFFSQtKGgEAYLGLFQEVIKLGNNRIDLASIRFSKSSEEAYQRIV--- ->tr|A0A0V8CQL1|A0A0V8CQL1_LACLL Uncharacterized protein OS=Lactococcus lactis subsp. lactis GN=KF282_1792 PE=4 SV=1 -----NPSHFMVIEEKKSKETVLEEISNILYKDKSVTIDFFNDLLAREALSSIVINDSIALPHPLN---DSVIKSTIFVAVVPRGLEWDENT--NVKFIFLLVIKSNevEELqNVYETLLDFIYSNDKQESLIKNPNYNNLLNIFT--- ->tr|E3GMB9|E3GMB9_EUBLK Transcriptional antiterminator OS=Eubacterium limosum (strain KIST612) GN=ELI_1876 PE=4 SV=1 ---HLTENDITIIDHIEDWSKALHLCSQVLIGKNVINTAYCEEIENSIHLYGAHfiLRNSMAIPHAGEK--AGVLGSGMHVLYIKDGVIFPDN--LKVRMIFFIASKEkELLINTVMRINAFSNDLNFYDVFDQKiKEGRCLAAYLKN-- ->tr|D1AKT2|D1AKT2_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_0213 PE=4 SV=1 ---FITKEEVSILDSVKDWQESIKTAGNLLLKNKKITEKYIDEIIHITETFGAHfvFQNEVAIPHGDAS--KNVNISSVSILKLRKAVLFPGE--KKVSLIFFISAKRkKDHVKSIEDIIKLMKNTEFIEKTNTVKNTEEFLELIKL-- ->tr|A0A1F3IV10|A0A1F3IV10_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_33_16 GN=A2W99_01860 PE=4 SV=1 ---FFSPENIEFYGDPINTDQLVLKLLQNLALnYGIGNvVSLFNNIYQNNRTKLLTNNCKPKIVTFPLH---NTDKTLIAIAIAKNNTD--NPPSESSELLIIITYPkanPDIILKVKKAFNDYFINPDFINEILQSKNSKSIWNIFDQ-- ->tr|A0A1E7E268|A0A1E7E268_LISMN PTS fructose transporter subunit IIA OS=Listeria monocytogenes GN=AJL15_11565 PE=4 SV=1 -----HEDLFLTNYEYDQKYNAIDFLSEYCISKGYVPTSFTEKLFSREQLFSTAIPTGIALPHPIK---NVAIKSGIFICIMKKPITWDNH---KVSLIMIPMIEelDGTEAPLINDFLSlIASNKSYVEQISKCSTYHECVELLQ--- ->tr|A0A1E7E129|A0A1E7E129_LISMN PTS fructose transporter subunit IIA OS=Listeria monocytogenes GN=AJL08_00810 PE=4 SV=1 -----HEELFLTDYAYEQKYNAIEFLSQYCIDKGYVPERFTEKLYNREQLFSTAIPTGIALPHPIK---NVAHKSGIFICILKKPCAWDTH---KVSLIMIPMIEelDGTEAPLINDFLSlIASNKSYVEQISACSTYRECVELLQ--- ->tr|A0A0E2VCH3|A0A0E2VCH3_OENOE PTS fructose transporter subunit IIA OS=Oenococcus oeni GN=EL27_07185 PE=4 SV=1 ---------LFRELNSVDKITSIKELSSLLSENRLLKekQDFLRLIYEREKQGNTLIAPRIAMPHAEG---ISVRKTGMAIGKSTKLINWNNN--QFVEMILLVSINPADeiNNEKLIRIIRELGKEEKTVHLIDSTKTNILR------- ->tr|A0A0R1R905|A0A0R1R905_9LACO Uncharacterized protein OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL001081 PE=4 SV=1 ---------FFMSLSSSDsSLDAFQTMAQRLSQLQRVSdvDAFTDLIVKREAQGLTMIAPQILMPHAVG---SVVLKNTVLVGLFPTLQHWNRG--LSVRLIVMLATPNAAaaqNDPQLMTLLTKLADEQVTEKLVAQKTVSQVQ------- ->tr|A0A1Q3RJU6|A0A1Q3RJU6_9FIRM Uncharacterized protein OS=Clostridiales bacterium 38-18 GN=BGO41_12430 PE=4 SV=1 ---YFSEEHYFREVDLETKEEVIEYMLQSMSIE---DVDTRRKILQREKTSSTERGNSVAIPHTNYL---FIESPRIAICLLKKPIIWHRE---YCQLVFLVLNGKqEkEPFIALSIAKAATGNIQFVYDMIRTKNFKEAHEVLE--- ->tr|A0A1T4K9F4|A0A1T4K9F4_9BACT Transcriptional antiterminator OS=Anaerorhabdus furcosa GN=SAMN02745191_0410 PE=4 SV=1 ---CLDKNCCLFDVDAQTSEKVITKLSKQMIENAKITNGFEQMVLQREEISSTERGNNVVIAHSLFP---ASEKTIIGVAILKHPITWGQE---NAQLVFMVSNGNnEeQMFTVLQWLQLLVQDFEFVHECLNAKNFEEIRLAIE--- ->tr|E3FEW0|E3FEW0_STIAD Transcriptional regulator OS=Stigmatella aurantiaca (strain DW4/3-1) GN=STAUR_1137 PE=4 SV=1 ---LLTPERLVLQLSCANLDDALDVAAGRLAPAcpGMGAGELAARLRQREEDVSSAVGNGVAVPRVFQTE---R-PALATLVTLARPLQVETPDGLPLRLVVALMGPerGRSSLMQLAHVARLAN-QGLADQLAGAQHPHEVFQRLQT-- ->tr|B1C8U8|B1C8U8_9FIRM PRD domain protein OS=Anaerofustis stercorihominis DSM 17244 GN=ANASTE_01716 PE=4 SV=1 ---SINPSLIKITDDITSWEEVLRQGGDLLINAGYASKDFSDDLIKSANLNGPYfvIRKGVGLAHALSK--DSNYESAISLTVLKNGVKFNHPYNDPVKLLFSLVIKDsKSYLNIFNDVLKLSTNKDFTHGVINAKSEKEVYDIIVK-- ->tr|A0A1C6HDQ3|A0A1C6HDQ3_9CLOT Probable licABCH operon regulator OS=uncultured Clostridium sp. GN=licR PE=4 SV=1 ---LLRPSGILTGVHSCSKNEILKKLCTLMETSGNVTNAFYNTVLYRESLCSTYIGNGLVFTHGDSE---QVHQSALSIALLDTPIPWDDAE---VDLIFVYAFNLedleRNSIkmdDFFSIFIDITNENDRMNELRKQQDPDAFYNTFL--- ->tr|A0A0G9FFJ3|A0A0G9FFJ3_LACPN Sorbitol operon transcription regulator OS=Lactobacillus plantarum GN=IV39_GL000235 PE=4 SV=1 -----------------TYVTGVKKLINQEIQHGQLTPDFMQAWLNREQQSSSIFGDGVALPHVIDK--SGLNRILVTVGVFEKPVVFDNQ---KVNVVFLVAIPYkldATLSKILAQVYDLIrsitANSNIYNNLKNYDENQGLN------- ->tr|A0A0R1Y5T3|A0A0R1Y5T3_9LACO Sorbitol operon transcription regulator OS=Lactobacillus composti DSM 18527 = JCM 14202 GN=FC83_GL002145 PE=4 SV=1 -----------------DYFKGSEWLIQQEIELGQVNESFVDRWYKREQKKLNIYENGVAIPHVIDD--SGAPRVLLTIGYYEREITYAKR---KVQLVFLIGIPQkvdGQLSKALSQVYDFIfsvsQNQRIYHNLLHFDNKRPLA------- ->tr|W0HMW3|W0HMW3_9ENTR PTS modulated transcriptional antiterminator OS=Sodalis praecaptivus GN=manR PE=4 SV=1 ------PEMTFAIDDSVDKETVLTTLCHAAVRQGLIDPGYLQSLLAREKISSTEIAPGVVLTHGDPA---LVKRNFISLTRLAAPACWREG--RACDVIVLVAFKKaadgkiDSsIAGFYSMLARLVDNECAMKSLRQCKTPGELYRYFIS-- ->tr|A0A0R2C500|A0A0R2C500_9LACO Uncharacterized protein OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL001743 PE=4 SV=1 ----LSRDLFFNHMQFKTKQEALDFGAQQFESQGYTDDKFIHEILKREKLAATNFG-NVAIPHTMRM---KAKHTVMLVIMNDKPIKWSAES--SCRLIIMIAVSNKaVHvfGELLQVMISALSIKHNVELLLACDDYDQFATQF---- ->tr|B9XR60|B9XR60_PEDPL Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD0708 PE=4 SV=1 ------EGLIVPDLKARDMAGVILELSNAFQKHDPVWnaQRLNQAALGREEQMSTAMNFLTAFPHVRSK---DCPKMQFALGRASEPMEWGRPGSLKVQFVFLNAIPATealGYLKLLSGASKLGKEAALLEQFKAAATARELYQLLQK-- ->tr|B1ZR78|B1ZR78_OPITP Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1) GN=Oter_1280 ------DRLCVPACRGRDATSVLLELSLAFAEAGVVSdsLSLYNAALNEYFLTDRDVLGSVAYPVCRLS---AIEAPVFAVARSREPYTWRD-GFSSVRWVFLILTPQVqsrRLSRLLAAISELAHDDAALASLALAGNRDELLERLRT-- ->tr|A0A0R1JB71|A0A0R1JB71_9LACO Uncharacterized protein OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL001796 PE=4 SV=1 ---KLNKNNVFANLPMSNYdeVKALSLISYAVAKkLNISEQEVKSSFLSREATCSSSIGEKIAIPKASA---SEVSEPQIFAFTSEMPIDWVSVDDKPVNIFLAIVAKS---------------------------------------- ->tr|A0A0R1RLD4|A0A0R1RLD4_9LACO Uncharacterized protein OS=Lactobacillus rossiae DSM 15814 GN=FD35_GL002530 PE=4 SV=1 ---KLFRKNVYTDVELADNneIAALKLIAHTAADkLGVDEQELKSGLIVREAMSTSAM-GDIAVPHANA---SDIANPTVLAFTFAEPIIWGEAPTHSVDTVIALIMPR---------------------------------------- ->tr|A0A0R2C5P0|A0A0R2C5P0_9LACO Uncharacterized protein OS=Lactobacillus thailandensis DSM 22698 = JCM 13996 GN=FD19_GL001337 PE=4 SV=1 ---LLKKKNVVANVALDENneLAALKAIANRVAGkLDLAEQELKSGFFASGAQDAVIIGDEAVILRATS---STLTHPEAVVLSFDSPVQWGD-DNSSVDIAIAIVLPV---------------------------------------- ->tr|F0H1Z7|F0H1Z7_9FIRM Glycerol kinase OS=Anaerococcus hydrogenalis ACS-025-V-Sch4 GN=glpK PE=3 SV=1 ---IIKKDNIKFTDLKLDWKKALYLSAKPLLDDGSIKEGFIENIIENiEKNGPYiNLGKGIAIAHTKDS--SFVNEDSLSLLRLSCPVIVSNDEKNPIYNLFTLATTGsDKHLNYLSSLTKNLSDESILKEFEDATSRSHIHKLLNN-- ->tr|C4V0J7|C4V0J7_9FIRM PRD domain protein OS=Selenomonas flueggei ATCC 43531 GN=HMPREF0908_0041 PE=4 SV=1 ---------------AASIEQLANAAAHLLLA--EDAaaKDFADELLRRERIAPTWAa-PQMILLHGCFA---RQERARFGVMHLAHPLPYGG----gAVQTALVMLVPageAEMERQILGHVAAQIADRPTFADILARGDAAGIRRELEY-- ->tr|U2URG9|U2URG9_9FIRM PRD domain protein OS=Mitsuokella sp. oral taxon 131 str. W9106 GN=HMPREF1985_00647 PE=4 SV=1 ---------------VSDAKRLCMIAAEQICT--DRTarNSIMDAFLQRESKGSTIIkGHGIMVLHARTK---ASPAPRAGVLRLSAPFVSES----gIVRTVLVLLAVmeKEESAEAVGAISTGLFERDGFLSVLHDGEHGAVFQAISD-- ->tr|A0A075K8M0|A0A075K8M0_9FIRM PTS modulated transcriptional regulator, MtlR family OS=Pelosinus sp. UFO1 GN=UFO1_0939 PE=4 SV=1 ---------------SKTIEEMIQGVSSLLGT--NDEmvSQLAAALQDREEKGGTFItGHGFVLLHCRTE---AVKKLHFGVVQNAKQIYAMNGKGQkeEVTLGIIMIAPeksSEHAIETISHLSKMLVERPDFIRLLQEGAEKDAVREVSN-- ->tr|A0A173ZN06|A0A173ZN06_9FIRM Probable licABCH operon regulator OS=Mitsuokella jalaludinii GN=licR_1 PE=4 SV=1 ---------------TPHIEDICRAAGRAVSE--DVAaqQGIAEALLARESKGETILrGNAMVLLHARTD---FAPGLHFGILHLEQPMLYPEQD--geAVRTAVVMLAPqesSCEALETIGTVSAALLERWGLIALLNEGNQDAIYQELEH-- ->tr|A0A023X0C3|A0A023X0C3_9ACTN PRD domain OS=Rubrobacter radiotolerans GN=RradSPS_0353 PE=4 SV=1 ---------------GGSEDEAARLMCRSLVARGLAAdeAGLAQALTERARRGGIGIpGTAVALFHARER---SVERPSFSVHELDEPIMLEGMDGErmAVRRALLMVAPldlSSVGLETVSEISAAMVERPAVRETFERGDEENVLDVLRT-- ->tr|I4D6N2|I4D6N2_DESAJ Transcriptional antiterminator OS=Desulfosporosinus acidiphilus (strain DSM 22704 / JCM 16185 / SJ4) GN=Desaci_2512 PE=4 SV=1 ---------------STQVNCIIKGLLNELVEKKllNRQqaLSLRQTLLDREKLGAIIIpKKNFAIYHCASS---EITEPMIAVARLDKPANLINLLGKneKVTTAFLMLAPlyVKESLEIIGDISSSIIESSDFVTEINRSSNVeDCRALLEE-- ->tr|A0A0B5AMH0|A0A0B5AMH0_9BACL Uncharacterized protein OS=Jeotgalibacillus malaysiensis GN=JMA_05300 PE=4 SV=1 ---------------HKKFEKVLSKIDASLYEEELIHkkGAVTKSLTERESLGGMAIpDTGLALYHCKDQ---AVRQPVFRLYDLTSPYMLKGMDGEptEVSRLILMISPadpDHKGAEVLSSISGSLVEEEYTMHLIRNGNQQEVFQFLQK-- ->tr|A0A162MTH3|A0A162MTH3_9FIRM Transcriptional regulator MtlR OS=Thermovenabulum gondwanense GN=mtlR PE=4 SV=1 ---------------KKNIEGLMDEVIKYFN---dVVVdgNLLKEDLKRRMELSGCGVpGTGVYLLHAKSR---SVREPLFGVFGTKEKMFLKNMDGQkeGYRDFVLMLLPtegYKKTAEVFARISVLILEDKEFLTALKGQNESLFIKILLK-- ->tr|L0EGU6|L0EGU6_THECK Transcriptional antiterminator OS=Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4) GN=Theco_2760 PE=4 SV=1 ---------------ADDKQHLVDRIIAYAGE--nfSVSdpDLLKRDLENRERLGPLLMePERLAMLHCRSE---GIDEMAICLFRLGREVNWDI-EGRpaLVRTVLTMLGPlhgPKENFELASEISMSLIEEP-FIRSLTHGSPGEAKEAMQF-- ->tr|A0A0X8GZK5|A0A0X8GZK5_9FIRM Uncharacterized protein OS=Erysipelothrix sp. LV19 GN=AOC36_04930 PE=4 SV=1 ---------------SNSIEDYIRAMCLvAMTQ--SESepELVVKSMLNGGHKNSFAIpNTHLAFFHERSA---GIKKSTLKVFPLTQPIQILGLDNRnhWVNTFILLLAPeklEQYELELLSFTSSLIIDNEEAPGIFEMGDQNEITTYLVS-- ->tr|F8F340|F8F340_TRECH PTS modulated transcriptional regulator, MtlR family OS=Treponema caldarium (strain ATCC 51460 / DSM 7334 / H1) GN=Spica_2252 P ---------------GKDWNEVLQQLIYACKGLGCINdeEAAFAALAQRSTDHGILLpDNRSLFLHARST---AVTRPCFTIHRLREPLVVDAV-QWssAPRTILLMLAPqnlNDRDLSLLNEISVSLLDTTILE-YLEQETEQ---------- ->tr|A0A061NYM8|A0A061NYM8_9BACL Mannitol operon activator, BglG family OS=Geomicrobium sp. JCM 19038 GN=JCM19038_1455 PE=4 SV=1 ----------------RDVWQGIEASVEEMHRLGFVDhvDAIVTMLKERERVGGLAIpNTDIALYHGRND---AVRDPFFNVIDLEEAISLPSMIEGheWVKRIVVYAAPkeiTPHHLSFLSYVSTLFIGSEQDVKVFSEGKREELLALLEE-- ->tr|J9HV15|J9HV15_9BACL Transcriptional antiterminator, BglG OS=Alicyclobacillus hesperidum URH17-3-68 GN=URH17368_1109 PE=4 SV=1 ---------------GGKLADVIEQAAQDAVQVGHAVdaAGVKQAILQRERLGSIVLpGKGLAVLHARSN---ALTDCHIAVYRLRQAIAVKGVGVQkeQVDTVLVLLAKideELEVIELLGRLSAALVTDDDLVDALRTFDIDGLQREMLT-- ->tr|C8WQV6|C8WQV6_ALIAD Transcriptional antiterminator, BglG OS=Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / JC ---------------AQTMDDVIQLVGLDLVRQGRASdaGPIVAAIERRERLGSVVLpGRQLAVLHARTD---GIDGPFVGVYRLERPMWTRGVGEDePVAVVLVLLARvqeDPGAIDGLGRISAALVESEALVEALKSADEEEVRRRLYD-- ->tr|A0A1B7KN40|A0A1B7KN40_GEOTM PTS sugar transporter OS=Geobacillus thermoglucosidasius GN=A7K69_13955 PE=4 SV=1 ---------------SHSIKEVLAEACHQLWQKGIIRdsGKVLAELLRRERLGGLGIpETPLVLYHARSP---AVLFPSFTIYRLTKCQTVKGMHDQpvDVNTILLLLAPdsaSQETLSVLSHISTLVIKDEDSIALFAKGDREQAHSFLSH-- ->tr|A0A1H1P8U0|A0A1H1P8U0_9BACL Mannitol operon transcriptional antiterminator OS=Paenibacillaceae bacterium GAS479 GN=SAMN05444162_0666 PE=4 SV=1 ----------------eESLETLLLVACSRQELREAVLdpSVIAMQLIQREMQGTQLIpGTDLALFHTRSE---LVTQPVLMLFELEQPLDMEENdahdtDD-gtYLKRFLLMLAPrtlNRESLEVLSEISATLLDQ-AMIDTLATGKEQVIRKRLAA-- ->tr|A0A1N7IZX3|A0A1N7IZX3_9BACI Transcriptional antiterminator, BglG family OS=Salimicrobium flavidum GN=SAMN05421687_10384 PE=4 SV=1 ---------------GRDSNEFLHHIIGELAEKDLLPydPRVVQQLLDREEVGGLGIpGTSAALFHTRTE---SAGSISFTVHFLEHPVTVNSMDGDsiDADTVLLMLTPpepPEESLETLSFISSLFVEEEESREVLESKEEARLKQYFSR-- ->tr|A0A1M5BDK7|A0A1M5BDK7_9BACL Transcriptional antiterminator, BglG family OS=Seinonella peptonophila GN=SAMN05444392_12125 PE=4 SV=1 ---------------GWSNEEVIRQIGHDLISEGflRD-gqSWFEQTLL---------QlENGLSVYQFKGD---EIEQPFFAVYELQESIHK------GVDQLIILLTPkdaKKEVQELMLTL-ESLCQQSGAIEKLATNDPEIIRTYFLQ-- ->tr|A0A1H6GMQ3|A0A1H6GMQ3_SELRU Transcriptional antiterminator, BglG family OS=Selenomonas ruminantium GN=SAMN05216583_10613 PE=4 SV=1 ---------------AMTVQEAAAAIGKRVAE--DHAqaKEIEKALLAREDQGSTAIlGSHMIMLHCRSK---AVESLRLGIVHLGEYFLYPAEP--geKIRTAIVLLAPescSCYELETIGHLSSILLERWGLLEVLHEGDERHIHGELIR-- ->tr|A0A1Q3RQR7|A0A1Q3RQR7_9FIRM Uncharacterized protein OS=Clostridiales bacterium 38-18 GN=BGO41_03070 PE=4 SV=1 ---------------AKNSEQLLKQIADANAT--DSKhkKQIISVLQEREKLGSTVLqGEGIALIHGKSE---VIKEMTFSVWRLVKPITMQAF-RRneLVDKAVVMLIPenaSKVQLEVMSLLSKALVEDNLMIQMISDADEKLLLDHIKG-- ->tr|A0A1U9K8S4|A0A1U9K8S4_9BACL Transcriptional antiterminator OS=Novibacillus thermophilus GN=B0W44_12370 PE=4 SV=1 ---------------NVSLEDGLNDICRDFERSGLLSgaNSVVEGLLAREQAGGVAIpETSLALFHVRTE---EIEKPCVSMCELKVPALRKGMDGMrvPVKRALVLLAPlsmSEQRLSLMSSISALLIKSEAHTTVFEKGSETEIRALLAE-- ->tr|A0A212KA00|A0A212KA00_9FIRM Uncharacterized protein OS=uncultured Clostridiales bacterium GN=KL86CLO1_12464 PE=4 SV=1 ---------------LKSTEELIEFTAETVGR--SDLqrAAIARSLFARERYGSTLTpDGRCMLLHCRTP---GVSQAYLGVVWLDGCITVAD----gqRPRSALIMLAPqdgPRQAVDVLSAVGSSTVEYPWLVDALCTGDRDQCYAAVEQ-- ->tr|Q3Y3R3|Q3Y3R3_ENTFC PTS family porter component IIA OS=Enterococcus faecium DO GN=HMPREF0351_13057 PE=4 SV=1 ---IFDASMLKYHQAAQTWQNAIRISGQELLAKHSIEEQYVNNIISNIENFGPYmiIAPGVLLAHAGEQ--DGVLNNGFSMHVFHEPITFPGENVFPVSVIMTIAVKDRTSYHVVERIVQWVLDEETIFSLADEKNRQRIEQMIR--- ->tr|A0A1Q8E771|A0A1Q8E771_9STRE Uncharacterized protein OS=Streptococcus cuniculi GN=BU202_06155 PE=4 SV=1 ---VFDPTMLVYHQNheGLAWREAVQLSSECLLEHGSIEERYTQKIIRNIEQFGMYmvIAPGVMLVHAGAE--DGVRQNGLSMHVFEEPVIFPSTDGMPIQVIVVVAMDKQNSYPVIEGLIHWITQEESLFTLRDSGNRLKCIQKIN--- ->tr|S2LDZ6|S2LDZ6_LACPA Nitrogen regulatory protein (Enzyme IIA-NTR) OS=Lactobacillus paracasei subsp. tolerans Lpl7 GN=Lpl7_2300 PE=4 SV=1 ---------------IVNKTTILRTISDALSKvSGQSAPQIQSAFMEREGVGNTALESGIAIPHAVLD---GRQVPVLGVLSYPSGVkDWKDLNGQPVTQVLAILMGKdeitEQEANDIKRFFVKLASSDFLRKIARSKDSQTVVAVIKQ-- ->tr|A0A135YLK1|A0A135YLK1_9LACO PRD domain protein (Fragment) OS=Lactobacillus crispatus GN=HMPREF3209_02578 PE=4 SV=1 ------ENNFYIDNKHKNYKAVIAELSTKMSKSGIVGKDFENKLLEREKISSTAFG-LVAIPHAIDY---DSKFSQWFIYINPKGVDWLGQ---KIYLVFVLAYSskdDDEFRKVFDDLSTIVIDDKRVADLINSKNYNDFVNRITK-- ->tr|A0A1L8ZNA7|A0A1L8ZNA7_9BACI Uncharacterized protein OS=Bacillus sp. VT-16-70 GN=BLX88_08575 PE=4 SV=1 ---LLRPNLFFRNVEIESDIELITFLAQSIIQQGYAPDEFLPLTIKREKISSTAFGGMIALPHPFNP---CGYENVIAIALLKKPILWGETK-EKVQAVFLLSLKKdNEqEIqDLYDRLLLIMDQPSLQTQINKQESFTDFVAFW---- ->tr|A0A242DEP6|A0A242DEP6_9ENTE Uncharacterized protein OS=Enterococcus sp. 3H8_DIV0648 GN=A5875_002372 PE=4 SV=1 ------ENYIVKIKRVTDWAEAINCAAVPMIESGGILPDYPAKIIANYHEMiPhIVFGKEIAVPHANFE--SAVNQLGMCLLVVEEGVRFTEH--QYVHLILLLATPDkNSHLSAMLQLLDLSANDLDVQQIITAETKEEIHSILRKY- ->tr|Q8EVW2|Q8EVW2_MYCPE Transcriptional antiterminator BglG family OS=Mycoplasma penetrans (strain HF-2) GN=MYPE4470 PE=4 SV=1 -----KRDFINiFDEKNLSWEKAIKLCTDSLIKSKRINVNYIKAIINNINKYNSVitLSNKIAMPHASY--LDGVNKLSFTFNIFKHPVVFPGKSKFNISLIIILAPEDnEKHIKPLFELVDILKQEENVNRLLKMKDTNEIYQFILEG- ->tr|A0A1C5Y755|A0A1C5Y755_9CLOT Probable licABCH operon regulator OS=uncultured Clostridium sp. GN=licR_5 PE=4 SV=1 -------KFCQAGVEAETWEEGVWIAAEPLIREQYIRESYICEIIRvnREYNNFYLMGEELSMPHAAPS--AGVLRLAFSMATLKKPVKVPARNGKtaEVRVILILAAVDtKQHAGALEEVADIFDRQDAVERLLNSQSSENLYKVFQE-- ->tr|B9Y9G7|B9Y9G7_9FIRM Putative licABCH operon regulator (Fragment) OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_02473 PE=4 SV=1 -------------GRLNDKNQLLKKLCELAAQKyNFDLSELLASVLEREKLGFTSYGNYVAVPHTMTRI---SDETFITAGLLHTPLKWDED--NVVYLVILISLGKkENHdlYSLYSSLSKLISNKDFIETLIKTPSIDKLLDFIQ--- ->tr|A0A1Y4SGA3|A0A1Y4SGA3_9FIRM Uncharacterized protein OS=Lachnoclostridium sp. An131 GN=B5E77_00740 PE=4 SV=1 --------------ENMDWRDAIFQAAFPLLSGRYIDRSYIDAMIMNVEMFGmyTWFGNGVYLAHAKAE--NNVYRSGVALMTIRKGIMFREQ--KKVFLLIVFASIdQKEHLSVLKEVVKLCNNVDKIQALLECQDEEALYQTI---- ->tr|G1WK34|G1WK34_9ACTN Uncharacterized protein OS=Collinsella tanakaei YIT 12063 GN=HMPREF9452_01697 PE=4 SV=1 ------QEFFSIEPDVANWREAIDLMGGRLVDEGYAFDDFCERLLEREEMSSSAYC-DIALPHPVD---MDARRTAVSVALFPRGLSWQGR---TVHAVLMLAIKRDDrafFSELFNHIAVVLTIPGAMRSISRATTYQQFLDAML--- ->tr|A0A243VZS8|A0A243VZS8_9ACTO Uncharacterized protein OS=Actinomyces sp. CtC 72 GN=BW737_12455 PE=4 SV=1 -----TDERLFVHTkSQLDRDDALRTCHSLLAREAAVDDQHLEDVFDRERRASTAFGGRFAMPHSLYM---DAARTALAVLTSTRPIPWGGH---EVNLVIMMAVSPrDraVFRDVLDELVRILSDPAGVDALIGAGTsYSRLMETL---- ->tr|C5EEI0|C5EEI0_9FIRM PRD domain protein OS=Clostridiales bacterium 1_7_47FAA GN=CBFG_00739 PE=4 SV=1 ------QELFFPDIKAADKPDALRQIIERVGKAVKLKESFYESVMEREKIVATELPNGFAFPHPLGT--DMAECSFFSISVLSNPIRWKHR---KIQIVLLTYVKGkvTSDLEQfYESFATLVSNKEYAVSLIENPTYEKLVEV----- ->tr|U1LYE9|U1LYE9_9BACL Uncharacterized protein OS=Exiguobacterium pavilionensis RW-2 GN=M467_10625 PE=4 SV=1 -----------------------------LMEQVNIDPTYAETVYARERTGPTSIGQSVAIPHGNPE---HATTNRIDVLVSNEPIEWGQE---KIQLVFLLQFRDSDatfSSHLFEEIAALTENPTLVRKLIGTKDDTAFRKLL---- ->tr|F0Z0M0|F0Z0M0_9CLOT Putative phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Clostridium sp. D5 GN=HMPREF0240_02651 PE=4 SV=1 ----LNEGVVQVKFQAESWQEAVREGVSLLEKTGAVEASYADNIVSNILQmGPYmAIMPQVFFSHAENN--GNVYSAAISILTLEKGVTVGRDDCDPIRLVITLAAPDsTAHLRAVAQLFSILRKRDNVDKIINSKNCASIVKIIMQQ- ->tr|A0A1K8HIZ4|A0A1K8HIZ4_STAAU Putative transcriptional antiterminator, BglG family / PTS system, mannitol/fructose-specific IIA component OS=Staphylococcus aureus GN=ulaC PE=4 SV=1 --DLLPEHRIIINKQPLSIESAITVAVQPLINDGIVNSNYTAAILKQLEQFGSYmvISPHIALIHAGTDYV--QNGVGFALTYFTEGIFFGSKANDSVHLVITLATDhPNAHLKALGQLSECLSNDLYRQDFLD--------------- ->tr|R5EHY1|R5EHY1_9GAMM Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 OS=Succinatimonas sp. CAG:777 GN=BN779_00897 PE=4 SV=1 ----LPKTQILSPLFCFSKKRLFEEIAEC---AAFITkktsKEIIVALNEREKLGTTVFFQGVAIPHAVIQ---SSTPTFAVLSILDKPITFNSIDAdeQLVDIAFSLFISpkDdVEKVeSLLKSLTIVLSNVDLLNAMRLSKNEKHkVETIL---- ->tr|S6CIV2|S6CIV2_LACCA Transcriptional antiterminator OS=Lactobacillus casei subsp. casei ATCC 393 GN=LBCZ_0237 PE=4 SV=1 ------------HINESSSEEAIEYLLRKSEY-----LNLLPYFQKRESMSPTDIGHLVAMPHPFLKG--AETTAKVIVGINRQEIPWGHQ---KVRLVVIYIPAadLKTNKNFFNDVYEHTSDLAEVHALLETKTKQEFIDVWNR-- ->tr|C1A8X6|C1A8X6_GEMAT Uncharacterized protein OS=Gemmatimonas aurantiaca (strain T-27 / DSM 14586 / JCM 11422 / NBRC 100505) GN=GAU_1644 PE=4 SV=1 --DLLSAARLRVPMSAATLADAAHELARCLEEGGSLShPELLQERIEEARpEDVVGLADRAFVVHYRTE---AVKDLVVALGRAVKPVCRVLDdeEKQCARIVILVCSPPrqlARHLQVVGAFARALSKPAHVDALLAADTPGAVMGLP---- ->tr|A0A0S8HC16|A0A0S8HC16_9BACT Uncharacterized protein OS=Gemmatimonas sp. SM23_52 GN=AMS25_05530 PE=4 SV=1 --RLLPPDRIVVGLKATTCEGAVAQLLDRLAAAGLISdRGAVDELVAADVsaGELLNLGPRTLLAHYRTD---AARELAVAIATSATPFAFAPAKADEAVVFVLIVAPRsaaKYHLKTLAALSRLLGTPEVVDALAKATSAEEVVELI---- ->tr|W0RIA0|W0RIA0_9BACT CBS domain containing protein OS=Gemmatirosa kalamazoonesis GN=J421_3277 PE=4 SV=1 --DLIVAERIVVPLQADDLPGAARELLARLVASGAVSqPERLRERVEEERpEDLVGMGNKAFLLHYRSD---AVRELVVALGTAPSPIERELGeseETQSARIILLVAAPPrqaSLYLATVGAFARLLSKPQVVDAVLAQPTADGLAALP---- ->tr|A0A202DI68|A0A202DI68_9BACT Uncharacterized protein OS=bacterium F11 GN=BVX98_07205 PE=4 SV=1 ----LTAGTILFLEPSEKKSMVLKPLVQRICENDPsVPlQRAFQSVMEREKVTSTFTQTGIALPHARLPK---LTRIHAALGVLPHGFQSPKEGAPLTNFIFLFLSPEgelSRHLQVLSKASWLFQNNTLKESLFQTNDPTKALSLIQA-- ->tr|A0A1V8YY66|A0A1V8YY66_ENTGA PRD domain protein OS=Enterococcus gallinarum GN=BH745_13345 PE=4 SV=1 -----KEPLFICDQDFETKEEVLHFLCHCINEQYQMPNNFEALVFEREAFFGTDFLPMVAFPHPNVLI---GSETVIAVAHLKKPIFWYKQ---SVRLVFLLVIAEQDHLKAksLnDHLIKICTSSEKVNELIATNDFITFIHHLK--- ->tr|G5IMN2|G5IMN2_9CLOT Uncharacterized protein OS=Hungatella hathewayi WAL-18680 GN=HMPREF9473_04760 PE=4 SV=1 ----FQKELFFNDIQAADKDEIIREMVARISRVRTISDDFLASVLEREQMQDTSFG-SVAFPHTNGI---ISNEDIISCAVLPQPVNWGNS---RVQIVILVSYREdfvKKHDTFFEFVLELIKKQGMVNKLKTEP------------- ->tr|A0A0U5K1I8|A0A0U5K1I8_9CLOT Putative licABCH operon regulator OS=Clostridium sp. C105KSO14 GN=licR_4 PE=4 SV=1 -----RPERFLPHISGNTKQEVLANIYKVIQSQEKVDDDFLELVMEREQLIQMNYGTQIAIPHPLHIA---SEHSFAYVAILPEPVSWNGS---PVQVVLLISIGrtgDSEEMrRLFyETTARFSLNKTAVEALIESPYYSTFIQLLKN-- ->tr|B9YDX3|B9YDX3_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_04047 PE=4 SV=1 -----SEKLFYRNIQIEGYENIINMMTDDAQKLGLCHSEFKKEVFDREQLSSTAYDSSIAIPHSLY---SNCKNSFMAIMINDEQVYWDDH---KVNIVLLIGVKTgdENFfKTIVDNIIPFFSENSNILKCLSINTYDDFVEKLSN-- ->tr|W1XN09|W1XN09_9ZZZZ Nitrogen regulatory protein (Fragment) OS=human gut metagenome GN=Q604_UNBC13982G0001 PE=4 SV=1 -------------------------------------QRLVGAAVGVDKHRAVGLDHDEALGSGKVG----VQAT-------GVVHGAGGNDNQPVDLLFALLVPAdqtKTHLHTLSLVAKRLADKTICRRLRAAQS------------ ->tr|A0A1D7QZQ5|A0A1D7QZQ5_9BACI Putative licABCH operon regulator OS=Bacillus beveridgei GN=licR PE=4 SV=1 ---LLPENRITITDEELNCEESVFQSVELLEHKLCVLPDYKHAVINRLKSNGPYmlVTHHVALLHAKPE--EGALEPSMSLLLCKKGVNFNKPGFDPVYLIFSFAATDdYSHLQALSELLLVVGEQRHVNALREMQDTREIRPYLQ--- ->tr|A0A139TLX1|A0A139TLX1_9BACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Akkermansia sp. KLE1798 GN=HMPREF3039_03180 PE=4 SV=1 -------------QPDTTQEQALETLVDSMAEVldERQSRHIKNAVLLREETQTTYLDHGLAVPHGRTTA---LDSMYVSVGISPEGIRWPDGA-QTAHLIVMLGVPTvmvTGYLTTMQKLLRWHKNAPLGP------------------- ->tr|A0A1C7PCG1|A0A1C7PCG1_9BACT Phosphotransferase/anion transporter OS=Akkermansia glycaniphila GN=AC781_05895 PE=4 SV=1 -------------GPVQTRAEALNVLSEGATEGlsPVLSAKVLAHAEVREESVPTYLENGLAVPHARVAG---LPGISLMAAYLPDGVPWPDEA-SMADLVIFIAVPMsqvSDYLFIIRKIIRWHKSVPCAE------------------- ->tr|A0A1W1IGC6|A0A1W1IGC6_9LACT Phosphotransferase/anion transporter OS=Trichococcus pasteurii GN=TPAS_1629 PE=4 SV=1 --------------EVHGKSELFDYVSGYLLKAGKIDsaEVLQEELRWRESMGNTLIEEDFAVPHIESS---NVNETSMILTRLKYPvLNWKDDY--SANTILFMLIKKEeepEILQDVKRIIKSLAYEETIELLKQA-EKRKIDIVL---- ->tr|A0A0E3ZBC1|A0A0E3ZBC1_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_02310 PE=4 SV=1 ---ILKEENIIFNYDAKDIYDALEKGCSLLEG-EFTDKSYTKDILSIYEKNNSHiiRYNGLILPHTKNN--NNVHKTGVSIISLKEPVNIKETG-EMIDTVVSFSIKDeKKSLDIISNLINMVFKSEFK-EILNEKNKYKIVEYLKN-- ->tr|A0A0P8GBG1|A0A0P8GBG1_ECOLX Transcriptional regulator (Fragment) OS=Escherichia coli GN=AN669_27725 PE=4 SV=1 ------------I--------FERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALNLPXTWVAER---LPrLKQRY--------------------ERTcCLA-sRP-------------------------GLGHF-------- ->tr|A0A0L0GZT3|A0A0L0GZT3_9ENTR Frv operon regulatory protein OS=Trabulsiella odontotermitis GN=GM31_15860 PE=4 SV=1 ------------NARDEAWQSVMANICKRLTNDGHLTVDEAWRIEQREREGENLIVNQLAIPHCWSERQ---THFRGYFITLAQSVSVNNE---PVSHVLIAcASASaRQELKIFSYLASVLYRYPP-TTISGLSGYEDFLALLRG-- ->tr|R2T7G5|R2T7G5_9ENTE Uncharacterized protein OS=Enterococcus pallens ATCC BAA-351 GN=UAU_00858 PE=4 SV=1 ------------VQKNESWFEILERICSRLEESLVISREEATKIIEREKSGNPLLINNYSVPHCISKRE---NFVICIYIHLDKPVMVETT---MVSHVLLTmMNPNvNKSINIFKFLYRYLQEHEE--QLATIETYDEFIRFVEK-- ->tr|A0A1G3MTI1|A0A1G3MTI1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWC2_52_13 GN=A2Y31_12505 PE=4 SV=1 ----VSEDSIFLDRDFKTVREVHEFLSDEFSKDlGMERDTILGLLEEREQLSSTWIGHNTLLPHNHSP---EIKGISMIFIRCGAPLVLGDG--NRVKYIFSILTSGsnqDLYLGILQGIGKVIGKRS--GELDNCQTPAEVLDILSDS- ->tr|A0A1V6JK76|A0A1V6JK76_9BACT Putative amino acid permease YhdG OS=Bacteroidetes bacterium ADurb.Bin008 GN=yhdG PE=4 SV=1 --------------DSsIGLKKLVGSIAHDICHDfgTVDAKVLTKKLLKSSIVDPILIAPHVTILHGNLE---SLVRPALHVITSLTGIEKTAGkeeaNgNDYIRVLFILVCPGknpKLKFRLLSRLMDIVDRYNFIEKICSLTNEREIKEYLLH-- ->tr|A0A1Z9BMG2|A0A1Z9BMG2_9BACT Amino acid transporter OS=Rhodothermaceae bacterium TMED105 GN=CBC65_04160 PE=4 SV=1 --------------QFkKDYESLLTQVANHMTSRiNCDANLLRAR-FAEGPDDHAMtLAEGVCLHHVRIP---NATSSEMVLV----RLAKPTVfkeLgDESLHAIIFLASSThnaTQHLRILAHLAEVIDNGSFLAHWDKAKDETDLREILLR-- ->tr|A0A1N6XSC7|A0A1N6XSC7_9BACI Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) OS=Domibacillus enclensis GN=SAMN05443094_10541 PE=4 SV=1 ---------------SESKESALNKMSVSLSANDIIEDsaFFYKEIMEREQLGNTHIGSGAALVHSIA---QTVKQEGIYLYYLSNPLtHWHFNETHPIKLIVLYAIQSvdSVNLKCFRKFSSLCADDELLQELIDQQySVEAIKKY----- ->tr|H3NPQ9|H3NPQ9_9FIRM Uncharacterized protein OS=Helcococcus kunzii ATCC 51366 GN=HMPREF9709_01331 PE=4 SV=1 -------NSIYLkHLKVKTKNEILKSLSLEASKYiNLEKEYIYTQFQNRERLGNTSFSNGVAIPHILEP----VNtDTFMIISSLDKPIIWDDN---KVKIIISLFIGKdNGDMTLfYDKLGTYLNNIEAINNSANFQEIEEFLELFLN-- ->tr|A0A1D4VHX8|A0A1D4VHX8_STAAU PTS system mannitol (Cryptic)-specific transporter subunit IIA OS=Staphylococcus aureus GN=ulaC PE=4 SV=1 --------------HVENIDEAIAKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSE--KHVHKTAMSMMILQEPIYMSDG--TAIHIIVPIAAVDkVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEILKN-- ->tr|E5VW69|E5VW69_9FIRM HTH domain-containing protein OS=Anaerostipes sp. 3_2_56FAA GN=HMPREF1011_02244 PE=4 SV=1 --------------DTQDWKYIIELLFSDFSENRYVSENYLADVLQRESILSFSLQPSVTIAYSMKA----SSKTVLSIATLEHRIKINSH---KTRIVILAAFRLE-ERTMLFRLINeLLYSGANLNDSRFLKTKEEFLDFFER-- ->tr|A0A1Q9JIE6|A0A1Q9JIE6_9FIRM Uncharacterized protein OS=Eubacterium sp. 68-3-10 GN=BHK98_07595 PE=4 SV=1 --------------GHGDPYSIFRDMAADFINAGFVTSDFLNDIIRHEENSTYAICPGVAYIYSLIP----AEKSAMSILTLDHRITWNTH---KIRVFIMTCFTLE-DMPITFRLANlFYDEAYDLPKIKMEENPDVLTRYYLS-- ->tr|A0A0R2BZW3|A0A0R2BZW3_9LACO Uncharacterized protein OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL001297 PE=4 SV=1 --------LILWNKKmPTDKESFLKAISDYLANEQLIAnsQKLLIDLKKRESVGNTIVYPGLAIPHTQS---SSVQETIMLIASLKEKVSWSEGE-TVSKVIFMLLPvhPQKSDLLELKKLFVQVADDEFMVKVLTG-SRKDIQQL----- ->tr|A0A0E9FFJ9|A0A0E9FFJ9_CHLTH PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC OS=Chlamydia trachomatis GN=ERS095036_14029 PE=4 SV=1 --------------------------------------TWLXSLLKREELESTEIGKKFALVHGNQ---KYIKNSSLSFIKLREPIKWKVD---TVQYIFVIAAKAEDYskysMKEFFKIINIVLNNGD---LEAIDNYEDLLNLFF--- ->tr|S0L4R9|S0L4R9_ENTAV Uncharacterized protein OS=Enterococcus avium ATCC 14025 GN=OMU_00045 PE=4 SV=1 ----LSAHQVHFKKTVDSFDTILDILASGMLIEGSISPNYITALKKEGFHEHLIIKDGIALPHIKDD--QHIYATSISLLKLEQPILLANEE---ISIFILLAADeKKEHLRAFEELFCILENEKLYDALLQISDYDSLNKVLKE-- ->tr|G1VUB2|G1VUB2_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium 2_2_44A GN=HMPREF9022_03593 PE=4 SV=1 -------------NTCESVSDFFLQSCQTLQDLHYVSDTFYDQLMERERLLSTSFETGIALPHTTE---NNARKSGILFAKFHTPMQWHKN---KIKCAFLIVTAkEDIHlLNIIyKVIVDISSSNQHVNRLYKCQTSEDVKRLIF--- ->tr|A0A0R1HNU5|A0A0R1HNU5_9LACO Uncharacterized protein OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL001420 PE=4 SV=1 --------------EITDIETFMQVVEEIALRKKLIQagNNLRVDIKAREAMGNTRVGVDTVMPHVKA---EYVIKPTVLIIRVRQPLTWQDQ--LPARVFIILLVRePDPFL---EDFIIRLVNEDFIDELADFNQPPES-------- ->tr|A0A1X7QHY6|A0A1X7QHY6_LACCU Putative PTS system, galactitol specific IIAB component OS=Lactobacillus curvatus GN=LCUFL03_220002 PE=4 SV=1 --------------RVT-KKDIFQIIRNSATQTKTIDlsDTIIQDLILREKDSSTRIAKHTVMPHVIA---DYVQKNMILIIRLDHPVQWLDK--GEVQTIIVLLIRqNDSYL---ETFLEMCCDELFLKELSQAQYSVAD-------- ->tr|I5BSZ2|I5BSZ2_9RHIZ PTS transporter subunit IIA-like nitrogen-regulatory protein PtsN OS=Nitratireductor aquibiodomus RA22 GN=A33O_18659 PE=4 SV=1 --------------TSITRKAALWALAAQVAtfRPGLSKIDIASALYARERLGTTAIGGGVALPHTVL---SGLEESMIVVRRLERPVEFEAADGLAVDTLVALMGGrHDiKWLrTALLRLNRLGKDTSLAQRLREATTRSEAVAAIK--- ->tr|B0M9X7|B0M9X7_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Anaerostipes caccae DSM 14662 GN=ANACAC_00350 PE=4 SV=1 -------DLLFFEEaAGKGWRQIIKKMGKHLECRGCISEQYTEDAIASVDEWGPYmvFIPGIAFVHAGPE---HVRIPGAALTVLDQEIPFGEEGNTYVKCIVMFAVED-EGNRLLTDLVSILERGDNVRKLLEAEAADDL-------- ->tr|D4H3L5|D4H3L5_DENA2 Putative PTS IIA-like nitrogen-regulatory protein PtsN OS=Denitrovibrio acetiphilus (strain DSM 12809 / N2460) GN=Dacet_2355 PE ----ICDSTIMYRLCGANRDEILNQILTILGRFTTEeKINIKKNLLFKESIISSSLS-GVAVMVADYDQQVNHSKTVFAVAYLDTPLDFKAIDGKKTDIAILIIPANKTEQLILtTRLNGLLNSDEFVKTLRSAPTRSTLIQRIRE-- ->tr|A0A1F9MDX6|A0A1F9MDX6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFOXYD12_FULL_50_9 GN=A2511_09815 PE=4 SV=1 ----LANGAVLYRIHGNNRDEIIDELLAALPYSSTFdANTVKVSILARESLVSSSLD-GIAYMTTAGSLPVFFEKTMVLMAFLEKPVDFKALDSRSAEAIFLVLPANTIEQEILdRKLRRLSMSPRFLTGIHQQMTRKLLLDFIAQ-- ->tr|A0A0R1JGV2|A0A0R1JGV2_9LACO Uncharacterized protein OS=Lactobacillus nasuensis JCM 17158 GN=FD02_GL000582 PE=4 SV=1 --------------AGQTVQAAMTDLGRYFQEHAIIAepAAFARAVAKREALGSTYIGAGIATPHYVAP----GLTPTLVIARSQSPLAWPDG--HTVHLCLVLVLPPGGADAQMIKLMTALADATWLQRLSTATLP----------- ->tr|A0A0A2W0E1|A0A0A2W0E1_BEABA Stationary phase-inducible protein CsiE OS=Beauveria bassiana D1-5 GN=BBAD15_g904 PE=4 SV=1 ----------NFTSRHLSWQQSIRKAAQPLREKGIIDAQYVRNMVKQIEdHGiTTYLTPDILLLHDAPP--AGATEGALSLLKLKYPLHFELSELSlTPRLIVIFVPTsNLSHIQLLEEFNALISDDKRLEQLLNADSLSQVKCCIH--- ->tr|A0A1B9KG08|A0A1B9KG08_9GAMM Uncharacterized protein OS=Gilliamella apicola GN=A9G13_00590 PE=4 SV=1 ----------GISRSQLNWHKAIDLVGQPLIKRGLIKTNYLQEIKENINkFGmYMYLTPNIVLLHASPI--DNQHLPYLSLLKVTKPIPFKIGQKSaAASIIFLLVPEkTASHIKLLEQLNVLLTNEQKLNDLLKANNIDSIERVLF--- ->tr|A0A142WR71|A0A142WR71_9PLAN Inner membrane protein YbaL OS=Planctomyces sp. SH-PL14 GN=ybaL_1 PE=3 SV=1 ----LLPDHAVFDLQAATSEDAIAILARRIPPTLLPEgQDIAALAVARERELSTDVGLGVAIPHARCP---GLSRPLLIFGRAASpGIRFSVQSSEPVTLLFLLVTPLekpELQVVLLGKLAGLAGNPEIRRQLGEAFTGEEVHQLLQE-- ->tr|G5HDN2|G5HDN2_9FIRM Uncharacterized protein OS=[Clostridium] citroniae WAL-17108 GN=HMPREF9469_00694 PE=4 SV=1 ----FKPEYVQKVTRCDNWEQALKLAAEPLIQDHRLSREYVDATIENCKINGPYfiLREGFCIAHALPD--KGLIKPCLGLLFIQEGVDFGHEFFGPVHMLFYTCFREsgQWNLKILRSLISLAEDNVKCGEIA-AQDCQRMYEG----- ->tr|A0A1B3CFQ0|A0A1B3CFQ0_9PSED PTS fructose transporter subunit IIBC OS=Pseudomonas corrugata GN=AXG94_19535 PE=4 SV=1 -------------------------------------------------------------------------------------ATLEA-----AEWVLLVAS-GpvdLSRFvgkrlfrstpaLALQDVDSVLRRGAEEAA---------VLVES-D-- ->tr|R4I1J0|R4I1J0_9GAMM Fused fructose-specific PTS enzymes OS=Serratia symbiotica str. 'Cinara cedri' GN=fruA PE=4 SV=1 --------------------------------------------------------------------------------------SLAD-----AELVIIVGK-TtlaNAILndklvyigelkHAIRKPQAFLKQAKILAK---------IYQAP-N-- ->tr|A0A1B9NRN3|A0A1B9NRN3_9GAMM PTS fructose transporter subunit EIIBC OS=Gilliamella apicola GN=A9G44_12205 PE=4 SV=1 --------------------------------------------------------------------------------------NATS-----ADVIVAVGS-GtisDKAVvgkkvyavddlnQIFANPKQILTDAQSKAS---------VYQQT-A-- ->tr|A0A1Q9GJ63|A0A1Q9GJ63_9GAMM PTS fructose transporter subunit IIBC OS=Photobacterium sp. 13-12 GN=BIT28_13865 PE=4 SV=1 -------------------------------------------------------------------------------------AQISE-----AECIVIAAN-TavdTTRFkgkkvyqsgvdACLADPKAYLEQAIAQAS---------VLKNV-Q-- ->tr|A0A1Q9YDF7|A0A1Q9YDF7_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium NYU-BL-F16 GN=BM735_06990 PE=4 SV=1 ------DECFEIEPEGKSPQEILKAMSLRLAKLNLAPGKLMESVLERESLCSTAYE-GFAIPHPLHP---CAFRPSISVALFPDGFNWNGT---IIYCVFLMSLRNDDlslFREVYEPLINLLVHPGLPEILSKSKNLESFKKT----- ->tr|A0A1Q7KS53|A0A1Q7KS53_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium 13_1_40CM_3_71_4 GN=AUJ03_00040 PE=4 SV=1 ---RLRPELVHVAPPWRTFGATVTGLVDSLVSAGTLdaevRDDAVRAVMTREDESSTAlLDIGVGVPHARLA---GLRQAVVALAVSRAGLYEPVP-TVPVATVAlVLSPPSatADHLRILTDIATLLRSPELRAALLAAPDADAALAAL---- ->tr|E6D927|E6D927_CUTAC Uncharacterized protein OS=Propionibacterium acnes HL110PA4 GN=HMPREF9578_02005 PE=4 SV=1 -MSMLSPDRFMAMPAGTDYWSATEALVAYLVDQGLVDETFLTTLRARENEATMLLDGLVGFPHATIP---GAERIVLAMATIPRR-----PEQPGARVVFLMGVPDKtDyddtiLITVYDEIIRLTNDPDLLNRLSQLTSYEDVFWLMAS-- ->tr|A0A143Z020|A0A143Z020_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system eiia 2 OS=Trichococcus palustris GN=Tpal_2789 PE=4 SV=1 ---------------QMGYFDYVEEIMIYLSKRYKLSDDILDRFIEKEERHTMIYENKVAFPHLTDP---NVDKLIFVLGKIKADK-----RYDGFSLMLFLITPEkitEQqekiLMQVYDFVFKVINDTVLIDKLQQISDVQGFIEMLEKR- ->tr|H3NFI2|H3NFI2_9LACT Uncharacterized protein OS=Dolosigranulum pigrum ATCC 51524 GN=HMPREF9703_01313 PE=4 SV=1 ---------------EFTYEEKVLVALREIEDDPTLINKLFNIFKEKESENSMVYENNIYFPHITNP---SGDNIKIVVS------------NEVDQLFVFLSIPAkmtDSqeylLTKIYDKIFNLIATQELKSI--DTTSFEKFMNYGDDR- ->tr|A0A1T4P9S1|A0A1T4P9S1_9FIRM Lichenan operon transcriptional antiterminator OS=Garciella nitratireducens DSM 15102 GN=SAMN02745973_01991 PE=4 SV=1 ---------------KDDYVTAVSHMIHELVKKGQLDGSFYQRWKDREQIQEMIFDKGIAIPHAVNK---NHEKFVLSVGIYDKEIK---QNNKRVKVIFLMGIPEkidKEnqkiLTFTYDKIFSIGINEVLYQEMLEVQGVEEIKKFLLRK- ->tr|A0A1E5DZG0|A0A1E5DZG0_9VIBR Uncharacterized protein OS=Vibrio rumoiensis 1S-45 GN=A1QC_12240 PE=4 SV=1 -------------------------------------EIIETQLKQRESMSSTGMKNGIAFPHIVS---EGVTDPQLFCVTTTTPIQWGSNFG-PVTHIMCLILPKpfqKEAFLGVKNLASKLVNEDFQQFITQQNTGAELQVI----- ->tr|A0A1V3HDD2|A0A1V3HDD2_9GAMM Uncharacterized protein OS=Salinivibrio sp. MA351 GN=BZG78_02320 PE=4 SV=1 ---------------ATQCESLFREIVERVAEKDT-SMQAHAAFMAREAHSSTYLGDQVALPHIID---SSVPHPAIIVTRCQPAMTWLNQE--SVSLCIAIAIPCdieRTTLRAISRLSRRLSSSAFRRWLTHCDDIPT--------- ->tr|X1FNZ1|X1FNZ1_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S03H2_03767 PE=4 SV=1 ----LKKENIEISLMGKTREELCMELLTLLEKGNKIQdKNFiLKSIITRDKVIDSYMGKGVIFVRLPL---ETQKNISLAMGVNKEGLDEEVFDREKIKIFLIIITPDsenEEYINLVSEMSSLLNQGSIREDILDAKDAERVKKILLG-- ->tr|A0A0E3ZB98|A0A0E3ZB98_9FUSO Uncharacterized protein OS=Sneathia amnii GN=VC03_00295 PE=4 SV=1 -----------CKIKFNTWEDTIRYGVSKMVELGIVNDDYANKIIDTINEYGSYmiITKNIALPHAKVEN--ENYKTGVYIIYLKYPIIFPGR--KRVKLLFFVHINCDDSRELIDNILQIIDNGQDLNKIQNV-------------- ->tr|C2BFG8|C2BFG8_9FIRM Putative ATP synthase F1, delta subunit OS=Anaerococcus lactolyticus ATCC 51172 GN=HMPREF0072_1088 PE=4 SV=1 -------KNLFFDIDVASKEEFFNVSQKLILKNNsEMTDKKLDVVENYDYSVSTDIGNLVAIPHAVLE---GDFKSFVAIFRLKNQIIWNKE---NVKFVFLIVINKkeKFYIDELKYLYNYILDPSNLSFMINASNYDEFVERI---- ->tr|A0A1V4RIJ0|A0A1V4RIJ0_9BACT Uncharacterized protein OS=Gemmatimonadaceae bacterium 4484_173 GN=B1H09_03165 PE=4 SV=1 ---LLSDSEIRFPEKTSTRSSILRYISLKAVELGAIYdaAELREQLELREEVVSTALRCGAALIHPLEINRMYIEKELLLLVIPPRPLPFGESSGRLTSLFFLLLFPNsHRHVHILARLNRLLRSSAFIETVLCARSHEEVLDLVYR-- ->tr|A0A095XWB0|A0A095XWB0_9FIRM Uncharacterized protein OS=Peptostreptococcus sp. MV1 GN=HMPREF1639_02535 PE=4 SV=1 --------------TISGGNELIGACTNLISRDKSERDRIYTALKDRCDINMPYFeDLGLYLMHCKI---KGVK-SRLGFMNVVEEFESLSGYngkriQKKIKSVV-VLILEerdLYAKDLFASISSRLVeDDEFLEAIS-CLDRSKIQYIVD--- ->tr|N1ZJ96|N1ZJ96_9CLOT Uncharacterized protein OS=Clostridium sp. ASF356 GN=C820_01111 PE=4 SV=1 --------------QIADIWDIIPLAGRMFTKEKKMADAVIMALKSREMKSETYIsSLEIMLFHCKT---DVVNHCRFGYIGLRKPFC-RKDGTGWVKGAVVMLTPEygtKVCLEVISTISSALIeNEKLITYLH-SIHQEAFVITLE--- ->tr|B0A809|B0A809_9FIRM PRD domain protein OS=Intestinibacter bartlettii DSM 16795 GN=CLOBAR_00753 PE=4 SV=1 --------------DCDDLEELINYSSFIFANNSKSALQIQKDLKRRINISTPFVdGIDIALLHCMT---EEVENIRYASIRLSNEIMIDKE--NKTKYALFMLIPKeaqTYQRELLSNISENLIeNDEFVDCIK-HGDKEDIKGKFK--- ->tr|U2NQY7|U2NQY7_9CLOT Transcription antiterminator OS=Clostridium intestinale URNW GN=CINTURNW_1729 PE=4 SV=1 --------------RFDNIEGIILEASKIAAKSANEEEVIYKALKEREKMSSTVItGKKFVLVHSSV---P-IPTYTFGVIRLKSGLSC-KNGngdEETINMAVIMILSSnhsKEYMEVMSYISRTIIdRDKFLKQIN-EEKFDFLYAQLC--- ->tr|U2NJM4|U2NJM4_9CLOT Transcription antiterminator OS=Clostridium intestinale URNW GN=CINTURNW_3555 PE=4 SV=1 --------------EITTKEELIEKTSILFSKDNNEKALIKAGLLYREKLGSTFIeELGISLLHCTL---DSFEGVKFGLIRPKKEVE--DF--PNLKVVVVIIVPKknnTILLKTVSEISEAIIqDENLVKDFI-VKDKEQLLNYLE--- ->tr|V9H696|V9H696_9CLOT Uncharacterized protein OS=Clostridium sp. 7_2_43FAA GN=CSBG_00131 PE=4 SV=1 --------------DIGDLEEIIEEASKLFSKDRKEAEEIKNKILDREKVNSTYLkDLNILLLHCKC---KCLDSGRFGYLKIKGQFK-NEK--GVIKGVLISIIPEdykEITSELMSKINGAIIeNERFLNILN-EKDSKEASQEVE--- ->tr|E4RK49|E4RK49_HALHG Transcriptional antiterminator, BglG OS=Halanaerobium hydrogeniformans GN=Halsa_1170 PE=4 SV=1 --------------KYKNLEQLLSDAAELLADNGDEKKVIQKDLSLREEKGSTVLeHNKILLLHCRS---KVVEEVKFIVIRPENKFKI-LNEdknKAEIEIVVVMAAPLkgaEQGREVLSEISRLLIeSTSFIKAIN-SGLKNEVYFEMA--- ->tr|F9VJ29|F9VJ29_ARTSS BglG family transcriptional antiterminator OS=Arthromitus sp. (strain SFB-mouse-Japan) GN=SFBM_0210 PE=4 SV=1 --------------TYGSIQNVIRDF--VYKTLSYNRDEIFHEILRKEMISSSYVkELGIIILHTIS---KFSKDIYIGSYILSKDIPI-YN--GNLNIIFYFIIPEelntKVLRKVIGELTSNLVkDDTFIDILK-KQDILIIREYIR--- ->tr|H3KAU2|H3KAU2_9FIRM Uncharacterized protein OS=Megamonas funiformis YIT 11815 GN=HMPREF9454_02365 PE=4 SV=1 --------------NVNSKEELCSFVSIYLLK-ENISQILEADLKSREEKGSTIIk--DLMLLHTKS---KVIQNLTVGIIQLEKSLKI---NEKEISTVLILLVPDkvdEKALETMGVLSESIIeNTNLLDILH-QGSKAEIYLELE--- ->tr|A0A1J0GDT3|A0A1J0GDT3_9CLOT Uncharacterized protein OS=Clostridium estertheticum subsp. estertheticum GN=A7L45_05265 PE=4 SV=1 --------------EMSSVDALIIEASKAIEKDSETTEKIRMALESREKKGNTVVtGHEMILLHCRT---DIVQKLYFGAVKLSKGLEC-LNGegkIENIKLGIIMLAPEecsALQIEVIGYVSKMLIeRVDFLKYLK-DGERDYAFNELN--- ->tr|A0A1D8GKY6|A0A1D8GKY6_9CLOT Uncharacterized protein OS=Geosporobacter ferrireducens GN=Gferi_19700 PE=4 SV=1 --------------DVKDVDSLIQEICIEFVDNTEERTRLYTDLKNREQLGSTLLkQKEIMLLHCRT---STVKELHFTVFRLQKPIYT-RGMngeTERIQAGTVMLAPYdaeKIGLEVLSEITKGLVeNDHFSSSII-EGEREEIYNDLS--- ->tr|A0A1E3KZT0|A0A1E3KZT0_9BACL Transcriptional regulator MtlR OS=Paenibacillus sp. TI45-13ar GN=PTI45_04275 PE=4 SV=1 --------------SATSVTDLIHQIATTFTASAERADVLEQELHERERLGETVLsQDGLILLHCRS---SVVPKLFLGVMRFAHPISA---AsqSVDLYAAIVLLAPKdssKSYLEAVNEVSKSLIdRPGFVTRVV-SGSAVELTAEIS--- ->tr|A0A1C0ABM8|A0A1C0ABM8_9FIRM Uncharacterized protein OS=Orenia metallireducens GN=U472_04290 PE=4 SV=1 --------------AIKNYDQIIKEVSKkDFIPLNTDSKAVYNALKAREEKGSTIIpEMKLTLLHART---DGIQKPFIGLVILDEAILL-SGPnnlKQEVDRIIVLLAPKeliSEEIQLISSFSASIIeNKDFHNVIR-EGNQEELIDYLR--- ->tr|A0A0K8JIB7|A0A0K8JIB7_9FIRM Uncharacterized protein OS=Propionispora sp. 2/2-37 GN=P22_3478 PE=4 SV=1 --------------SARTKLTLIEYIAKnMA-AEESYRELILKRLLKREEYGSTVIdEGGLVLFHCKI---KDC--LKIGVIRLLSPIEA-VSGdvQSAISTAFVILMPDdadDRIVEMLSAISKGLIvNKNFLQEVC-KGTKEAVLKHLS--- ->tr|A0A1M6GC20|A0A1M6GC20_9FIRM Mannitol operon transcriptional antiterminator OS=Dethiosulfatibacter aminovorans DSM 17477 GN=SAMN02745751_01689 PE=4 SV=1 --------------KAGSMKEIIDYSSSLIGRNPEEVDILIKAFAEREEKGTTILsKKGMLLLHCRA---DISMEVCLKILSLSNPIEL---KqgdEQLIDTIVIMVGPVvinQKILDTMSEITRSIIa-SDFSELIL-SKREEEIEFELN--- ->tr|A0A1T5IPA2|A0A1T5IPA2_9CLOT Mannitol operon transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_00599 PE=4 SV=1 --------------DFDNHNELIKYVSTLIGESKEDIDIIERDLLAREEQGSTVLeGKRMMLLHCRT---NGVNSLKFGVVRLFEEkpIFC-KSGrgeEEILT-VLVMMYSSsknKGHLEVISEISRNLIdEPKFVDILA-KGTKKEIFISIK--- ->tr|L8EYL4|L8EYL4_STRRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Streptomyces rimosus subsp. rimosus ATCC 10970 GN=SRIM ----LPKQQIHPHAQAITANELLETLTHDLHAAGTISdpHTFTRALHTCLTHGTHGFH-GIALLTTRN---RTVNTPAAAFARISPDLAWHGADNHQIRDVFLLTAPHkpkhhSGCLQTYSTLARHTAHAGFRRMLAGACTAEELYELFC--- ->tr|A0A0M9XFG3|A0A0M9XFG3_STRRM Uncharacterized protein OS=Streptomyces rimosus subsp. rimosus GN=ADK43_15685 PE=4 SV=1 ----LPRQRIHPYARTETTDELLRTLTHGLHAEGTISdpDTFTQTLHTRLAHGPTGFH-GIALLAARS---RTITTPAAAFARIPRNLTWPSADDHTIHDVFLLAVLHrlidTGCIQTYAVLARHTAHPGFRRMLSASRTTDELYELFR--- ->tr|A0A1M7E3T1|A0A1M7E3T1_9BACI Transcriptional antiterminator, BglG family OS=Bacillus rhizosphaerae GN=SAMN05192535_3705 PE=4 SV=1 ---------CFFRLNGQTKEELLRLLVKKAG-----AEVYLPSIESREQLSATDIGNRMAVPHPLISI--DAPETKIFVGMNSRAVQWGER---TVQMVFLLLVSErdTvLYESIFREIYQLSKTARLQDM----KSYQGFRNSL---- ->tr|A0A0S4M0F5|A0A0S4M0F5_9BACT Putative PTS system sugar transporter subunit IIA OS=bacterium 2013Arg42i GN=Ark11_0450 PE=4 SV=1 ---LLPPANVLVDVEVNSVKKLFELMGVFFENRYSLsKDVVYQALFARERLGSTMLakSSGWAMPHAVIT---SISEVLCGLVLLRNSIVFDQRGWRASVFLFVLIPPSwRDRVSCVYNEWRLLSEQkDVVETVEGMDNPSALYQYLFH-- ->tr|A0A0J1FR43|A0A0J1FR43_9FIRM Transcriptional regulator MtlR OS=Desulfosporosinus acididurans GN=mtlR PE=4 SV=1 -------------LQAETYQDTIQDIVQGIHATHLIAdrARIYDLIAKREEKGNVIIpGRHIALIHFRAE---EISEPFVSAFRLKHFIEIKGIGYssENVDTFFVMLARKDesnYILELLGKISvALVENDYFAEVLRFG-DLKDIRSEL---- ->tr|E6U8C8|E6U8C8_ETHHY Transcriptional antiterminator, BglG OS=Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3) GN=Eth -------------VTATNMPGLIHTIASRLLEKSVVTdrEEIEHRILKREKIGSVVIpNSRLALLHTRSE---TVAEPYIGIYRLRGQMLLHNPHSndEPVDTFVVLLAKETahpLVLESLGNLSmSLVDRPALIETLRTG-LPEEVRQKI---- ->tr|A0A1W6WB45|A0A1W6WB45_9FIRM Uncharacterized protein OS=Ruminococcaceae bacterium CPB6 GN=B6259_00375 PE=4 SV=1 -------------IPKEPFEQMVDRIAAELFRQHRIAdpKEITHLILQREKTGSIVVpQTKVSLLHVRSD---LVHSPFVGVYRIaEGEICMRGVGFvwEPVNTFLVMLARSSetaSVLEKMGRMSvALIEDKTFPKMLRTG-TLGELKTKL---- ->tr|A0A1J6FDH0|A0A1J6FDH0_9STAP Uncharacterized protein OS=Staphylococcus equorum GN=A4A34_02950 PE=4 SV=1 -----------ISTNETDKVRLLSDLENQLIDEKILGkqNSLKKDIEFREEKGNLEIYPKVLLPHIKQ---QYVKKSKIIIIKNhSSLIKWGDQM---LKVVILVLVSndiSENEQKRIRIFMRDLADETYINKLIE--------------- ->tr|A0A0F4L7Z4|A0A0F4L7Z4_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_19430 PE=4 SV=1 ---KFSNDHCWFLSEVNNKQQVLEKISKILSDKQLVFPNYVNVIKKRERIGSTYIGENVALVHGIYK--EKHLVPSLNIFKLKKAINWSKNE--KVDLIINFVATknsEKDFKFIFQRMGKSIDDIQFWNSLKAIP------------- ->tr|A0A1V4RK22|A0A1V4RK22_9BACT Uncharacterized protein OS=Gemmatimonadaceae bacterium 4484_173 GN=B1H09_01670 PE=4 SV=1 --DILTKETIEVNVDLKNKKQLITEIAVIACK-------------------------HPAMKGIAPSEVEKLLSFAVGIITTRKGIDFNSIDNEKVNIFPFVIGPednPKEHLKVLSGMARLLRNPETRSTIRKAVSPQELYDFLEG-- ->tr|K8DVF8|K8DVF8_STAXY Putative regulator of sorbitol operon OS=Staphylococcus xylosus PE=4 SV=1 -VDFLTEQDVYHVNENMTYEEVIAYLSNELINENRVDYTFISKILEREKHKSTVTG-SLGFPHTSH----LYHGIWLKLAIINQPLQDYEM----VKLVVLVATPEAEvneaiLIRLYEEILAITTKSYIINQICKDTDYITLAHILNNE- ->tr|A0A143PD21|A0A143PD21_9STAP Uncharacterized protein OS=Staphylococcus condimenti GN=A4G25_08570 PE=4 SV=1 -LDFINERDFYHLSDADDYYSVIHFLASEMIDEQRVDSKFDQTIIEREKLKSTINK-AVGFPHATH----SMEGIQIKVAILDNTIKSYPD----LKIVILIATPKTIsneaiLIRIYEEVLSITKNTYLTKKITSQTDFEDFVYLLNEE- ->tr|A0A239Y7P0|A0A239Y7P0_9STAP Putative regulator of sorbitol operon OS=Staphylococcus stepanovicii GN=srlM PE=4 SV=1 -LGSMLENNFVYLTSNASYQDVIQEMVTGLPVSLDEQLIIQENLLIREDKKSTVYG-EMAFPHTSY----SGNKLMVKAGIITKHIEEEPH----LKLVILLITPNESvndamLIKLYEEILSVASNKYLLSKLNSETSYESFINILKLE- ->tr|A0A1R7MD26|A0A1R7MD26_CLODI Putative transcription antiterminator OS=Clostridioides difficile GN=licR_11 PE=4 SV=1 --DLIGTDTIRIIDGDMKWEDAVKISSNILANCDFVSAQYAENIIDILKNVGFYavKDNEFALLHGNDS--SLVKVSSISLLICKEAVSFGDKK---VKIIFCLASRDkKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYE ->tr|A0A0R1RYR8|A0A0R1RYR8_9LACO Uncharacterized protein OS=Lactobacillus fuchuensis DSM 14340 = JCM 11249 GN=FC69_GL001288 PE=4 SV=1 -LHLFNEENFSIVTDEHDYLALLKKKGLRLESMGAATPDFSKSVIDREQKISTVYDFGVAGPHPMA---SFAKKEVIDVTIVTNEMQYQQKE---VKIIFLINIRQGHltlHQEISRMMIELIKDRELRELMYQVKDYPSFISYIT--- ->tr|D7CUJ1|D7CUJ1_TRURR Sodium/hydrogen exchanger OS=Truepera radiovictrix (strain DSM 17093 / CIP 108686 / LMG 22925 / RQ-24) GN=Trad_2672 PE=4 SV=1 -FALLHREHVLLDLQTPSYAEAIERLLYTAIPKGGVQtQRVLRMLVEDDIGFSSEVLPGVLISHARE---RGIRQPTLCLGISRQGLSHYSSS-HTIYVIVLLLSPaelpMQAHLARLSEVSQQLAHAGQISRLVSCKTPEEVLAWFAQSR ->tr|A0A098QVP3|A0A098QVP3_9SPIO Uncharacterized protein OS=Spirochaeta lutea GN=DC28_11860 PE=4 SV=1 -QLDEPPVTYLFGFPNPQIKELCSELIARM--PDIAPsSRLIQDLLRISQEEPVLLVDQVVLIHSHR---KEVHKTQIAIGTADQDIRLPLVD-QSIRVVVLLLNPldqdPSVHLQILSRIARMIHRPEYLPALLSSRSQEEFQEKLSRIR ->tr|A0A0P7ZAK7|A0A0P7ZAK7_9BACT CPA2 family monovalent cation:protein antiporter OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_01730 PE=4 SV=1 -FGLLSPDAVSMSNENQDILTLIRQLIGSRLRIDGNKlESICAAVMDNSLEYIPEIVPGIAILDAHI---PDISETVVIIHISNDGIHIPKTS-GPTRITVLVLNPdhigIDLHYRRLNAVARIFRGEGIVERLTSARNEQEVLAVLQDTG ->tr|A0A0J7HQQ5|A0A0J7HQQ5_9BACT Na+/H+ antiporter OS=Chitinispirillum alkaliphilum GN=CHISP_1926 PE=4 SV=1 -KSVFRPQRMLFNMNTSSLNEMVFKLLQNEFRNDKALhNRLTSILCKIGREEPVELLQDVLLLHTYV---PYLSETITFLGVSKKPLDVPLAS-GSPHIVIVLLDPvgqdPANHLRALSDIANLIRLPSIVDILKEVKDYGQLVEKTNQIN ->tr|E3HBH2|E3HBH2_ILYPC Sodium/hydrogen exchanger OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_2016 PE=4 SV=1 -IRRLSKNNFLFDFSENNPEKLLKIITDKF--SDEREsREVYEDLKDVLKKYPVELTHETLLIHTYM---ESIDDYQVYIATNKNKFSVENVK-SNPKVIIVLLSPksdpMNRHLKVLSEIAKIVTDKKMLSDILGSCSYSEFLERINQR- ->tr|U7D4W1|U7D4W1_9BACT Sodium/hydrogen exchanger OS=Chitinivibrio alkaliphilus ACht1 GN=CALK_2173 PE=4 SV=1 -FEPIQEPT----------GTPLPQVLTALaenISPSKEDsMELFGLLMSCAEAYPVEISPGIVLLHAHT---CTVTTPRVFLFHQEKSETLTPID-KKVRLLIIVLNPfygdAQQHLKTLARIARIFAQKENQEAVETYADAESLISHLKISH ->tr|A1BHK1|A1BHK1_CHLPD Transporter, CPA2 family OS=Chlorobium phaeobacteroides (strain DSM 266) GN=Cpha266_1862 PE=4 SV=1 -T--EKKSMFNFS----YLGTLVDKIPKGGkrgLFTGKRNsSDTAA-------------------------------------------------------------------------------------------------------- ->tr|B3EE21|B3EE21_CHLL2 Sodium/hydrogen exchanger OS=Chlorobium limicola (strain DSM 245 / NBRC 103803 / 6330) GN=Clim_1681 PE=4 SV=1 -L--SGGIQFSMV----PLRSQVESMLKRVsfkRISLRRNrKEPQ--------------------------------------------------------------------------------------------------------- ->tr|A4SFP4|A4SFP4_CHLPM Transporter, CPA2 family OS=Chlorobium phaeovibrioides (strain DSM 265 / 1930) GN=Cvib_1291 PE=4 SV=1 -K--GLDTLE-------RFGKIFGEAYRK-gWKPLQRQtEK----------------------------------------------------------------------------------------------------------- ->tr|A0A0L8VB39|A0A0L8VB39_9BACT K(+)/H(+) antiporter OS=Sunxiuqinia dokdonensis GN=NC99_14920 PE=4 SV=1 -MEPFMEHVEHLD----DFRKMIGQFFKKK-------------------------------------------------------------------------------------------------------------------- ->tr|G9S5J6|G9S5J6_9PORP Uncharacterized protein OS=Tannerella sp. 6_1_58FAA_CT1 GN=HMPREF1033_02032 PE=4 SV=1 -M-DVQRDYTRFI----GLRLFLENLLKKKkrWGHR--NqKKDK--------------------------------------------------------------------------------------------------------- ->tr|A0A1G3P9C2|A0A1G3P9C2_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_00460 PE=4 SV=1 ---LHAIDYADFNIESSDIQKGIRTLLSKMYTGSIC-EALINEMVRVSNEEPVELCDGVILLHAHV---SEIKEYRIFFGVNKNGFDLPSCP-GKFHAFFMLLAPkeqsPEKHLAILAAVAKLVQAKQFLEKIESSQSLDEFKASFKDGT ->tr|A0A1G1C3E7|A0A1G1C3E7_9BACT Uncharacterized protein OS=Lentisphaerae bacterium RIFOXYB12_FULL_65_16 GN=A3K19_20240 PE=4 SV=1 -ENLLRADHVAFGLGSVGLAEAVDTVLGRCLAPNMALpAEKWQELRDALLPSRLELRPGVVLLHVHS---EDVDVPVVLWALSEAGFADSVTS-APARVLLVLLSPaslpPDQHLQMLSSLARTILAAPNPAAIAPVRSIEDLRKALTPSG ->tr|A0A1G0Z3R5|A0A1G0Z3R5_9BACT Uncharacterized protein OS=Lentisphaerae bacterium GWF2_50_93 GN=A2X45_04290 PE=4 SV=1 -GKLMSPDRMVFGLEYENPEKAVKIILSNFLKGRSSDpESTASMLADELLPTALEIIEGTVLLHVHC---ENTDEPTVLLGTCSTGIPFSGID-NPAKSIFILLSPasdnPEEHLQILSDIARFALSMKNSDILHKAKNLPELETLLMIHK ->tr|A0A1F3F5U0|A0A1F3F5U0_9BACT Sodium:proton antiporter OS=Bacteroidetes bacterium GWA2_30_7 GN=A2046_13315 PE=4 SV=1 -NGLIEKGVNRIT----IGAKNISKIFKKEsdsSEI----------------------------------------------------------------------------------------------------------------- ->tr|A0A1V6BWV7|A0A1V6BWV7_9SPIR Glutathione-regulated potassium-efflux system protein KefC OS=Spirochaetes bacterium ADurb.Bin133 GN=kefC PE=4 SV=1 -FHFIENRNFYFNLNNLPIKNAFNYILKEKFGKTPEVlNELSDILSDIAINEPLTLLPGVILVHTHI---SQIEGHIIYVGVNRSGFDIPNIP-EKINIMLVLLTSteqpPEYHLNLLKEIVHLLKIENFVESVSKSNSFKEFEKTFKAGC ->tr|A0A1V4MXW7|A0A1V4MXW7_9BACT Uncharacterized protein OS=Candidatus Aegiribacteria bacterium MLS_C GN=AVO35_11095 PE=4 SV=1 -REIFPPGRVLLHMTETDGEEALRILIKKGYGQDEALeEE----CLRQLRESPLWLSGDCVMVHTHE---AGPPAPMALLATARNGFDLNGRT---ARILLLLLGTpgetPEEHLGRLAVVAGMLHGKETASAVVETSDYDTLSRMLSDNT ->tr|A0A1V5Q8H2|A0A1V5Q8H2_9BACT Glutathione-regulated potassium-efflux system protein KefC OS=Verrucomicrobia bacterium ADurb.Bin345 GN=kefC PE=4 SV=1 -SALLRSDRFFPGLDDMSVESAVGTMVRAALPQHPSVaDRLARQLADVAKQYPVEFAPGVLLLHSHA---GEWGEALVMAGVSRKGIAVPGLE-SPVKLLLLVVADrhqrNEEYLRVLADISRVLQRPGIIARLMDISSPVELDRVLADTE ->tr|N2ANE5|N2ANE5_9FIRM Uncharacterized protein OS=Eubacterium plexicaudatum ASF492 GN=C823_02279 PE=4 SV=1 --------DFFRVDNRISFGELLIAIGEKMSPYSDCQEIIREDILKREQIASQVFAEfGFALFHART---KGVTRPAFSVCMTKDLGVFADAYFKGIRIVFIMLAPADDHIKingdIMGYISSMLIEDYEFIDIVVRGDKEEIRSALSG-- ->tr|A0A0V8QCG4|A0A0V8QCG4_9FIRM Transcription antiterminator BglG OS=Acetivibrio ethanolgignens GN=ASU35_03260 PE=4 SV=1 --------TAIKVDNNIGFDELLLAVSEGLTPYHDRQSMIQEDIRHRESLGTQVFSElGFALLHTRT---RGVLRPNFSLCFTKDKGVFANPFFNGIGAVVIMLLPEDEHIRenreILGYLSKQFIEEPDFMDIILRGELEEIREEVSR-- ->tr|A0A099I5T6|A0A099I5T6_CLOIN Sugar lyase OS=Clostridium innocuum GN=CIAN88_15625 PE=4 SV=1 --------LLHISDSDTLSQLLI--ESAEyIGKDAAAVEQIRADLQKRESMGPVIMQDlQFALLHAAT---SAVDTMEILLQYPRH---AWSAEAKNLKFAVVMLVNTQAGR-vrkeLLSLFSRGLVESETLLEAVCTQDIERIEEALSQ-- ->tr|C4G9M5|C4G9M5_9FIRM Putative licABCH operon regulator OS=Shuttleworthia satelles DSM 14600 GN=GCWU000342_00678 PE=4 SV=1 --------CDYETDPKISFPDLVYQLADRVTESQAVAEKIAGKIQRREHLNSQIFPElDLALLHCRS---RMIREPVFISCRPSGDRSFADPDFKGIRAVIFMVMPEDEQLRmhmqILGQISASVIRDEAFVGAILHGDEELVKKELKK-- ->tr|G0VNS3|G0VNS3_MEGEL Uncharacterized protein OS=Megasphaera elsdenii DSM 20460 GN=MELS_0879 PE=4 SV=1 --------QQFTVPASSTFAQVVHTLAAAATKGEEDTALLFDAIIRRECLNSQIFPDqGFALLHCRT---QTIRQSLFYTCVPDGP-AFEDDYFKGIATVLLLIMPEDEYRQvhtdVLGFISSSLVSDDAFYQAILGHDPEKIRCHLQR-- ->tr|E5VQQ7|E5VQQ7_9FIRM PRD domain-containing protein OS=Anaerostipes sp. 3_2_56FAA GN=HMPREF1011_00329 PE=4 SV=1 --------RIYPADASEGKEEVLRKLLGHTDMGEKQKDRCLEAVMEREKDGPVALKDrKFLIFHCNI---PGNNTPVLMFFTLDHK-KGTHPDFQDFDKGALMIVDKKQDK-ktrdTLAVISEGFVNDERILESLEKKDPKALRCQIRE-- ->tr|E2SNI3|E2SNI3_9FIRM PRD domain protein OS=Erysipelotrichaceae bacterium 3_1_53 GN=HMPREF0983_02702 PE=4 SV=1 --------HLHTTQQTTLSDILM--ESAQyLGRDEITAAQIREDLQKREAMGSVIMQDlHFALLHALT---PGVDHMEILLQYPQT---AWDEDLHNLKFVAVMVLHTESSR-irkeLLSVFSRGLVESEPLLHAVIAQDQQKIEEALSQ-- ->tr|R9LMQ4|R9LMQ4_9FIRM Uncharacterized protein OS=Firmicutes bacterium M10-2 GN=C815_01788 PE=4 SV=1 --------VFVTVPSQMDLSQLIEEASVL---AKGSPSQIVKDLHRREELGSILIPElGFGLLHTKT---TGIEKPQVQFLWPDQ---QYFTQYENIEVVFVLLLPYEANS-ydqkLLSLISTHMMEDDRLREAVFAHEERHIQQVLSS-- ->tr|F5YNL6|F5YNL6_TREPZ HTH domain protein OS=Treponema primitia (strain ATCC BAA-887 / DSM 12427 / ZAS-2) GN=TREPR_2966 PE=4 SV=1 --------TVIRINADCSFDYLFRFASDRFAPLAR--ETIYNKLMDREKISSQVIPDlGVILLHTRS---DAITIPVFAILKPD-GEKFKDEYFRGAKSCVVMLLPEAAPA-emtdLMGGLSSALIDVPAFLDAIHDGNEKVIKALLEA-- ->tr|A6LQT2|A6LQT2_CLOB8 Transcriptional antiterminator, BglG OS=Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052) GN=Cbei_0524 PE=4 SV=1 --------DLYTLSSEITIDEAMKFVSETIGGNEESKNYIYNDLMKREQVSTQVIKEfEFVLLHART---KGVEASKFILIKPD-SAQFDDEYFSNSKVIVVMLIPEDDPRGilAISSISSALFDDDLFLNDIKSGKKEIIQSYIEK-- ->tr|A0A140DX49|A0A140DX49_9FIRM Uncharacterized protein OS=Faecalibaculum rodentium GN=AALO17_20920 PE=4 SV=1 --------VRIPTGTVYDPAVLIHEAACSl----QGDTEILEQDLWRREQLGAVRAPEeGFALFHART---GGTARIQAAILLPAGG-Q----YDNGLRGVLVTVLPADHTP-pmqqLLAQVNRQMGQDAGFRQVLLSGPAQAAREATDR-- ->tr|A0A1F9ZPP6|A0A1F9ZPP6_9FIRM Uncharacterized protein OS=Firmicutes bacterium GWF2_51_9 GN=A2Y20_03615 PE=4 SV=1 --------DIVVLDPTIPMTKIFSTIGYRIGKDKKSGKLIVDDLRQREKMGSIHLEEeQVILLHAKT---AGVGSPICMVFRSN-ASSFQDPEMNGMKTIVVLLAPVNVNP-iiqeLMSRISAGLLEDPSFLFAIHREESARLRESIEA-- ->tr|A0A1C0BVU8|A0A1C0BVU8_9FIRM Uncharacterized protein OS=Erysipelotrichaceae bacterium MTC7 GN=A4S06_01995 PE=4 SV=1 --------SIETLDYRSNKEDVMK-ACASmVSQRADHQEELVLALKKREALNTTVFSDlGLALFHGQG---AYVEQGVVKLIRPNHE-AFICEELSNIYFVFAMFLPENSNR-eqlqMLSMLSRKLIEDDNFYQACMSEPHAIVYQKLEM-- ->tr|A0A1H7HQY4|A0A1H7HQY4_9FIRM Mannitol operon transcriptional antiterminator OS=Pseudobutyrivibrio ruminis GN=SAMN02910377_01096 PE=4 SV=1 --------HHLKIFPLTSFEELVNSLSSDITESPKAAVILASEIMAREQIMSQVFPEvGIALLHARS---RAVKECIVVTASCENGQELAGEGLNGVKAVLCMVMPLDEHRKenseMLGRISSAIIDDESFLSAIQNGREDTIRNKLQK-- ->tr|A0A1M7GWE9|A0A1M7GWE9_9FIRM Mannitol operon transcriptional antiterminator OS=Caldanaerovirga acetigignens GN=SAMN05660826_00492 PE=4 SV=1 --------SLEK-VNTGTFEELLDAIGEKIKSKPGiiSVSEVKRDINERELKSGTAVPGaGISVLHART---VGVEKPFLGLFRLEKPLKmkSMDGGIEDVKACLLMLLPKKSSPKemeIMGRISAALIEEEGFAELLKDGADVEVIRSFIR-- ->tr|A0A1G7PWP0|A0A1G7PWP0_THETY Transcriptional antiterminator, BglG family OS=Thermoanaerobacter thermohydrosulfuricus GN=SAMN04244560_01438 PE=4 SV=1 --------TYMTAkgeNSSQIIEYILKNLIDENLINENQKEQIKGRLLKRESLGKIVLPNkGFVIYHCTI---ENIDFPLVVVGKVIEEVKmkNLVGDYEKIRTAFLMVAPEGDREGieVLGDLSMSLIEREDLVNTLNEAQSqKEVKEKIKE-- ->tr|A0A1U7NF42|A0A1U7NF42_9FIRM Uncharacterized protein OS=Ileibacterium valens GN=BO222_07980 PE=4 SV=1 --------KVVVAQKDSDPDSLIWQAARQf----EGNSSQIYEDLLRREKMGSVIAEDyGFVMFHAAS---SATKAPQFILLFPQEE-TFFAREYSSLHFIAAAIIPLEANK-yereNMSLISSSLIEEEAFLYSIISRDKKRIYDHLVR-- ->tr|A0A1Y4QPV3|A0A1Y4QPV3_9FIRM Uncharacterized protein OS=[Clostridium] spiroforme GN=B5E91_01050 PE=4 SV=1 --------KLYILQHEISKQELIESSCKL----TSNDPLLISQILEREQRGSNVYNNfGFALLHVST---KLVNNCLIRIFKANQS-EFSSDELKNVKVVLLMLIPDNATD-iqkkIMSYISAQLIENNDFFNQLVNGDIEKIKEAFNK-- ->tr|A0A0Q1AV10|A0A0Q1AV10_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_00030 PE=4 SV=1 ---------------------------------------MIDLACSREDLQETVLGKGVVLPHCRI---RGIREVLIIVGLSDQPFKWGKQE-DKAKIVILLISPavnPNLHLKALSFLAYQFRTKKDCIDVNSKNMEELVKEVILEKR ->tr|A0A1F2Z7S3|A0A1F2Z7S3_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_46_13 GN=A3B66_07455 PE=4 SV=1 ----IDFTAAHFGVKGDNPLQVIKNLAFTISrDTHNPSTILHSQLDGLLKNSMIGIGEGVGVFDWVS---KDIDTPYIMCSMLENSVTFPSVDDKSLDIILVLISPEKNgplHLQSLSRLTRMFRDAQFLASLRSVHSCDGMLSILCHD- ->tr|A0A1Y3Y046|A0A1Y3Y046_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_00860 PE=4 SV=1 --DSVPRRFVRAHIQAPNWESAVRLATGPMLQAGAMTEEYLQGIFDLSRRYQQFgvICPGLCMPHANA---DPDNELSLSLVTFERPFDVDMGQEHrvPIKVMFVIAPVDgSRHSRIVDELITLCDSFpKFVDDLAAAESSDELYRSFLR-- ->tr|U4TTY7|U4TTY7_9LACO Uncharacterized protein OS=Lactobacillus shenzhenensis LY-73 GN=L248_0506 PE=4 SV=1 ----------------------LTAVGTWLAKQKVAPnsQQFMETVLTREQAGSTSIGGGLMVPHYMQ---PGLSPARLVAVPIHAAESWPGLDGQPIRLLLITCFDPDQPQPAFQALLRGLASPTAAAKLVRQPDAG---------- ->tr|A0A0Q9VZJ9|A0A0Q9VZJ9_9BACI Uncharacterized protein OS=Bacillus sp. Soil768D1 GN=ASG99_18470 PE=4 SV=1 ----LHPSYILIQPKRLENEHSFEEMLAK-----MIDGTTSYKGfIEKKIVSETKVNNQFSVFLIDQ---KVVNETAVGINIIK-GVTPTDSK-----LEIVIAFKdRLSLNELLTEVFSLSIHKVVFERIIQAGTLSELEQILI--- ->tr|A0A0D7X175|A0A0D7X175_9BACL Uncharacterized protein OS=Paenibacillus terrae GN=QD47_13100 PE=4 SV=1 ----LLPELCVAGAKVSSREEAVANLTNRMHEMGFINSEFEATVFRREALTPTSLGNGVAIPHGEV---DHVLQSKIAVMSIPEGVDWGGEQ-----VyiVFLIALkLdDELSaKEILNDLYNLLDSDYNMNRLRICQDHQRLYELLA--- ->tr|D1AMM5|D1AMM5_SEBTE Transcriptional antiterminator, BglG OS=Sebaldella termitidis (strain ATCC 33386 / NCTC 11300) GN=Sterm_2754 PE=4 SV=1 ----LNKRYIQIENEIFSEKTNVKKLIKK-----IINENY-LEIrNAKEYISEIHINESFSVYLIKK---DIVTKTCVGFRIKS-SA-AGEYK-----ADIIIGVKdNDEIhRQLLREIFELYNNKELLKKICFCRNTNEISELIN--- ->tr|I9NQ37|I9NQ37_9FIRM Transcriptional antiterminator, BglG OS=Pelosinus fermentans JBW45 GN=JBW_04352 PE=4 SV=1 ----ISATDIYINTEDAFII-----NDLE-----HNNGQ-------KLSFYNVGFGREIQILLAGN---SNVKRFAIQIMNNT-E---DGNC-----IKFYILNPDYEHvKNIVVEIYHLYEAKNEMNYLLECTRTIDVQRFFN--- ->tr|B6G219|B6G219_9FIRM PTS system, Lactose/Cellobiose specific IIB subunit OS=[Clostridium] hiranonis DSM 13275 GN=CLOHIR_02181 PE=4 SV=1 ----FS------KYEVLKKE-----VLHD-----Y-------------NIPKFEFKDGLNIYINKN---NN-NK---NKVFIG-K---QNKK-----IEIFIDSNNDSYiKNTIIKTYSLYKDKNIDSLFME--------------- ->tr|A0A1R7D8P2|A0A1R7D8P2_CLODI Transcription antiterminator OS=Clostridioides difficile GN=licR_3 PE=4 SV=1 ----YLEDNIYFNFDVMQME-----SLIG-----VDLGS---------KYKSISLGKDLNIYIHNQ---SKLNK---GIMNVN-N---INRT-----IDIYLETSNQSFlKNILMEISNLYRQKSYINYIIDCKSKEDIKILFK--- ->tr|A0A1M5BY17|A0A1M5BY17_9CLOT Transcriptional antiterminator OS=Lactonifactor longoviformis DSM 17459 GN=SAMN02745158_03861 PE=4 SV=1 ----LPGGHITFGY---------------------WNGASARG---QKICESYLLPQCLAVVWKRK---DEKTE--VF-LTV----DTENEM-----LRI-DLLPgRVEHqKELLRELYRLTLEEKNVRAITRCRTQEEVQKCLR--- ->tr|A0A0Z8FYK7|A0A0Z8FYK7_STRSU BglG family transcription antiterminator, PTS system IIA component OS=Streptococcus suis GN=licR_3 PE=4 SV=1 ---------------GNTEEEVIRELIYHQIGKNAQAEQLIKEVADREKITTTSLAHNIAIPHTLS---KDLKCSSIIVGIHGKGILWGDKQ---VQLIILSLFSdkDKAGGEIFRKLYHFATNRDIVEKTIQERTTYYLVHYLEGDS ->tr|F4PG21|F4PG21_BATDJ Putative uncharacterized protein (Fragment) OS=Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) GN=BATDEDRAFT_29046 P -IFDFEPQHILLTEREMSWKEALEMALLPMKRRKSVTDKYCMKVKELFQNEGDRmmIGPSVYLPHASTN--NGVLYEDFSILLCKHKVEAPNGE--LIKMMIVLAPEDgNNHVSTLLFLNEIFLDEVKADKISGAETEQEFIELIHSFK ->tr|A0A0R1WUZ3|A0A0R1WUZ3_9LACO Uncharacterized protein OS=Lactobacillus kefiranofaciens subsp. kefiranofaciens DSM 5016 = JCM 6985 GN=FC93_GL000530 PE=4 SV=1 ---------VRYDLNEDSYYKSVKELVELLSKDNELTLDFYQRWTERKKKSNNVISNGIAIPHAVDN--SGRERILLSFGIIKKRVVYKKTK---LRFIALLGIPenlDSSLVKATSELYDFVsmivRNQVLLENAEKYNNERSFIQMLEG-- ->tr|A0A1Z9M1E3|A0A1Z9M1E3_9BACT Uncharacterized protein OS=bacterium TMED198 GN=CBD58_03510 PE=4 SV=1 --DIIDPNNIIVPIKSTIKEHAIQELLRHMEKNGNLSstAKLNDFINSQEKAFSSAAGKGVAFPSCGS---IEVENVIAVLGVSKNGVAFNAPDGLKCHLILLTLSSkkdPTKRRRLVHMFQDMISNIEIKYSMMEDGSVESIHNTI---- ->tr|A0A0H4T8B8|A0A0H4T8B8_9DELT ATPase P OS=uncultured delta proteobacterium Rifle_16ft_4_minimus_37851 PE=4 SV=1 ----LSA--ISLDVKSkdhdGVLTE-MSSLL--fKDIPGAVGDkTFCDL-KEHESMEGVLFGTNSAIFHCLS---EGVDDVMIAVSISGRGIPHPKKkkyR---INIFFLIVSPmkeSGTHLRIMSRVEGFLLDR-SFRHAVLSAKTADEVKKAVKRE ->tr|R8ZRM8|R8ZRM8_9LEPT Putative calcium-translocating P-type ATPase, PMCA-type OS=Leptospira yanagawae serovar Saopaulo str. Sao Paulo = ATCC 700523 G ----LNVDSIQILKDVkhwGDIQIALMKKIPELEIQKEIQYRFH----SIPNHTFETIGDQILIPHFRS---ANIKTPELFLFILPEGIKVGEKK---IQLVLFQMIPeqlPSLHLRLLHGLSSLLPQ--IFEKLMLCNQAVDVLSVVQLGE ->tr|A0A1F9JY90|A0A1F9JY90_9DELT Metal-transporting ATPase OS=Deltaproteobacteria bacterium RIFCSPLOWO2_12_55_13 GN=A2W73_11970 PE=4 SV=1 ----LKPEKIVIGLK-GELPQVLDRLFNRssfPDRVEEFRSALV----KGNSNPYSYIGNDIAVPHVRL---EGLSRPEMILGLSRAGMRLNGNV---VKILLFFATPaeqTEEHLQLLQRLTSLLPA--IKDELLAQRDTTSALKIIAKGE ->tr|A0A1V8ZJY0|A0A1V8ZJY0_ENTCA Uncharacterized protein OS=Enterococcus casseliflavus GN=BH739_12590 PE=4 SV=1 ----LLNSHVIRIDQKCSWEHSLRLAGKVLTHNECIEQSYVEEVVENVKQNGPYivISEGVALAHANNR--GNVHRSTISLLTNKQKISYGSEDYFQVTYVFFVALVrSEEYLEIVEDIM----------------------------- ->tr|A0A0F4LNM5|A0A0F4LNM5_9LACO PRD domain protein OS=Lactobacillus kimbladii GN=JF75_02650 PE=4 SV=1 ---ILPERRIAFENGTYSWQESVKVTGRLLEKDHIADEKYTHKMCMQIEKYGPYmkIMDNVMLLHAKPDNPTKFSVPGMSLVCFTPPVKFSNDI--KAKYVFSLYAPNsNSQLKALTQLTEIFSNRFLLEKFEHAENAPTFIKLFDS-- ->tr|Q034D2|Q034D2_LACP3 Transcriptional antiterminator, BglG family OS=Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441) GN=LSEI_2725 PE=4 SV=1 ------------NPANMSYEDVLRATLQGDSDAGIVDPGFIDRLIKHESTTKFVLDNGVAIPHAIAD--IDHDRLFLHLSVLKHAITVGGKS---VSYIFVIGIPrvlGKRALEDLSMLYDLLfllaVNETAMNNLRKISGSQDPLTVVTEG- ->tr|H1LIY2|H1LIY2_9LACO Uncharacterized protein OS=Lactobacillus kisonensis F0435 GN=HMPREF9104_02574 PE=4 SV=1 ------------------QEDALTELERAVTQQHVIDkpiDQLVDDIKKREQLGSTEIYPGIMMPHINEP---YVNQTTVVVTRFTQQAKLLGHSGIRAAIFVLT----NGATDALAEFMHLLVDPRPFEYLLD--------------- ->tr|A0A1M7LKX7|A0A1M7LKX7_9BACT PTS system, nitrogen regulatory IIA component OS=Fibrobacter sp. UWR3 GN=SAMN05720472_2228 PE=4 SV=1 -----------------------------------------NSLSERVKQGI-YMGDGLLLPHTRI---AGLERPLMAFCVCPAGFtGIEIRGGEKAQFMCVLLSPAESamaHTQAIAGVAKLILDPEWKARALAAPDDAGVKALF---- ->tr|A0A109RDP2|A0A109RDP2_9LACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Aerococcus christensenii GN=AWM71_02255 PE=4 SV=1 -------------------------------------------MREREELGSVQIGSYTVMPHMEA---EEIPSSKIYLFLLEKPFYWNDQASQIrIILTLFICPKKDSHKEKIRQVIRHFAEPHIEQKLLNSKDNHEVFNLLTN-- ->tr|W7CEE7|W7CEE7_9LIST Frv operon regulatory protein OS=Listeria weihenstephanensis FSL R9-0317 GN=PWEIH_10278 PE=4 SV=1 ------------NAPEEDWNTIVQGICRELEARDILSSDEAMKIQEREQKGNNLVINHLALPHCTT---QRNQAFFAVFVHLAEAVLVDGTL--VHNALVACVNPNvSTELKVFSYLYYVLNEHDS-EDILSLTDYAAFIDCIEG-- ->tr|A0A0C1YY96|A0A0C1YY96_9BURK Phosphoenolpyruvate-protein phosphotransferase OS=Burkholderia sp. MR1 GN=BurMR1_1444 PE=3 SV=1 -MAPVSGVMVQLESVPDPVF-----AQKMAGDGVSIDPTSDELLAPlsgtvtqlhRATHAATiTGASGLQVLIHIGLDTVMLRGEGFTPLV-KEGDTVTT-GQPLIRfdpVIVGARAVSL-----LTEM--VIANGELVTRYMPAtglvtagKDVALSVEFVGGKS ->tr|A0A1Z4PS59|A0A1Z4PS59_9CYAN Phosphoenolpyruvate-protein phosphotransferase OS=Scytonema sp. NIES-4073 GN=NIES4073_16110 PE=3 SV=1 -FNKVDGVVVvGIVIVSHskklaeGVRELAaqmvQGKVPLAVAAGIDDPENPLgtdAMQVYEAI-ASiYSDEGVVVLMDLGSAVM---SAEMALEFLPEELRDKVHlcEAPLVEgaiaAAVAAAA--GSHIQQVIAE----ARGALVAKATQ-lgVTHNLTPNPSPQAE ->tr|A0A212LI09|A0A212LI09_9RHIZ Multiphosphoryl transfer protein OS=uncultured Pleomorphomonas sp. GN=fruB PE=3 SV=1 -KPLLAPELTRLKAAPADKEAAIRQACALLADAGYIDPAYADSMMRREAVAETYLGQGVAIPHGMNADRGLIRHNGLAILQIPGGLAWNE--GQIVKLVVAIAAQSDDHIAVLRRLTRLFQDEAALEALFVTDDPLAIIAALDETA ->tr|A0A179YFI7|A0A179YFI7_LACRH PTS system sugar-specific IIA component OS=Lactobacillus rhamnosus GN=PY91_05325 PE=4 SV=1 --------------------------------------LVQQLVTRREREGETYIGYGAVILHLIS---ERVPQTTVLLVKSQTPLDWTSryaNQIHHVNKFVILAISPhDLDGASFRPVMEELADEASINQLFEME------------- ->tr|A0A075LLW0|A0A075LLW0_9BACI Uncharacterized protein OS=Terribacillus aidingensis GN=GZ22_14515 PE=4 SV=1 -----------TYQMQ---ADLFSQIDQHAVDHTVINkhGTLASLLRQRDELGGMGIpDTRMALYHSRS---TEIEQPAFWMMALSSPIMIKGMDNQVmeADRLFILAAPDNLPLScyELfSKISILILEEhIQHMIRSA--DQEALSKELAQL- ->tr|U1EDY0|U1EDY0_9STAP PTS lactose transporter subunit IIB OS=Staphylococcus sp. EGD-HP3 GN=N039_10140 PE=4 SV=1 -----------VNIEYTDVTEINDYLTTHLYQQQIINdvQSFADELQQRSLTQNYILdPYPIAIPHLKH---RLILRPYILVTILNQPMEVIDDQNDKhtIQYLLAMFAPEDDFSAEIiSRFSSAFANHlTELETLML--YPERIRELVKQS- ->tr|A0A0D6XPQ9|A0A0D6XPQ9_9STAP PTS lactose transporter subunit IIB OS=Staphylococcus microti GN=TP70_11000 PE=4 SV=1 -----------IIVSTAHCQNLDTALAHYLAELKVINntLEVSHLLKQRNQTQNFSLaPYPVAIPHLKD---KLIVKPHFSISKLAQPITSPD----QppIHYVVCAMLPENSQLTPLvSHLYSYITEHlEDIDTWMS--DQTEVEHALKQQ- ->tr|A0A178PK70|A0A178PK70_STALE PTS lactose transporter subunit IIB OS=Staphylococcus lentus GN=AXY37_01960 PE=4 SV=1 -----------MIFEQRKVTNLTRYLVQTLTKHHVLEnsNDFIEKFEQRTALQGFALtGYPVAIPHLSD---ESIKKPQLIITELIKPLSLKTIENKEqeVNWLVSMFIPANSEQGQLmSEVSSLITEHlDDINHLLN--DRVLIENTLKSF- ->tr|A0A0M2SN61|A0A0M2SN61_9STAP Uncharacterized protein OS=Salinicoccus sediminis GN=WN59_05685 PE=4 SV=1 -----------AFTESDTPLGTMDSVRNMLAEHSSLErhaaLDTVRRLAERFKITGHVIgEAGFSYPHIKS---PFIRSHQLIIVHNSAGITDRNYNGDAvtVNYQIILLVPEESLISDLiSEISVLLGEHhEDIGSLLK--EPSMLDVLFKNY- ->tr|A0A1S1F3H9|A0A1S1F3H9_9STAP PTS lactose transporter subunit IIB OS=Staphylococcus sp. HMSC070A03 GN=HMPREF2798_12590 PE=4 SV=1 -----------IYVEDATITNWQDYLAKRLAKHKSILskSQFKQVLKTYAEDRSITLaPYPIGLPHLKH---ALIVKPMVMITRLKQPLTIVE-QNQEhtINYLISMFLPEDNPSSPIvSAISEVITCNlHRIDELMQ--NPNEIIDEMKKA- ->tr|A0A1Q9ID52|A0A1Q9ID52_STAPS PTS lactose transporter subunit IIB OS=Staphylococcus pseudintermedius GN=UH47_12840 PE=4 SV=1 -----------FEVFHTDLTDWSYDIAQHLYHKKITHdlIAVQQLLKERHDKQSFVLsPFRVAIPHFIS---AHVEIPYIGVWHLATPYDFDE----GltVDTLFCVFLPEDTHLQPLvSEIYSQLSLAlDEHNDALT--DAEHIEQWIKQS- ->tr|A0A1W7A967|A0A1W7A967_9STAP Transcriptional regulator MtlR OS=Macrococcus canis GN=mtlR PE=4 SV=1 -----------IQFAVMEDEDFIAFAA--SKMQDKVNdlEAFQEALSYRNHLQGFLLtDSTIAIPHIVH---ESIHTAAIILAHNKNGVELKNMDGVMshAHYLVYMFLPEDTLLRPLiSEMSLLVMEYvSSPEKLFN--DEPFVIEYMKQA- ->tr|S4ZQ50|S4ZQ50_LACCA PTS system, galactose-specific IIA component OS=Lactobacillus casei LOCK919 GN=LOCK919_2816 PE=4 SV=1 -MTDLITPELVYFLNTPTQAAFFKTISTTLVDQQIMAPAGKEALITREQTFPSGMQlnevadglPNIAIPHLEG---ELVKQTRLVVVHFAIPVAFKDLADAsrilPVNWVFMLMNAEpQKQPERMAQLIRALTQSpaAQLKRLFAAKKAAQVARL----- ->tr|A0A0E2BMB0|A0A0E2BMB0_LACCA PTS system mannitol-specific IIA component OS=Lactobacillus casei A2-362 GN=LCAA2362_0629 PE=4 SV=1 -----------IKLGQeaKTKEEAIRQA------GQLLVdnGNVEPAYIDSMldrnrdvsvyMGNFIAIpHGTeagMKYIKSTA---ISIVQYPWGVDWsddpadenlVTVVFGIAGLNGEHLkl----------------LSQIALYCSDVENVQKLADAQTPEEIVNLLKE-- ->tr|A0A178HEG7|A0A178HEG7_9LACT Uncharacterized protein OS=Aerococcus urinae GN=A1D21_03560 PE=4 SV=1 -----------VNNTGkakLDLKSLLDQQIGQLR-GQQVGdsQQVSEAVMRRFEESAIGIpHSGIGLFHTSH---AEVFQPYFVIYDLAEGYPILGMDHQMMtlrRLLLLLAPNPltPWLQEVMGAISSSVIENDANLSLYDRGDEGLLKQLLNN-- ->tr|U5SAV6|U5SAV6_9LACT Transcriptional regulator OS=Carnobacterium inhibens subsp. gilichinskyi GN=Q783_09575 PE=4 SV=1 -----------VVGN-QPLEETLLWICRQLQDIGVLIeaENVQQKLIERVNIAPVGIpGTQMGLFHVRN---IDVASSYFGIYELEQEVPIVGIDRKDMvlkRILIMVAPYPlnVIERELLGLVSSMVIENDSTTALFDKGEEEAVRKKIEK-- ->tr|A0A0H4QND6|A0A0H4QND6_9LACO Uncharacterized protein OS=Lactobacillus ginsenosidimutans GN=ABM34_12515 PE=4 SV=1 -----------IDNRMFNLQQTLLLLSRRLRPE-FVSnpDQVATALYQRMQKAPVGLpNTTMALIHTTN---EGVRRPFFALYDLTNPILIKGMDYKSMnlqRCLFMIAPKDlpQFSTDLLGSISSSIIDNELNLRTYQQGSPEEIKQLIAK-- ->tr|A0A1F1QMI0|A0A1F1QMI0_9LACO Transcriptional regulator OS=Lactobacillus sp. HMSC08B12 GN=HMPREF3168_04975 PE=4 SV=1 -----------IGSQGMDMNAVLSAIVTAVPDE-YVKdrLEVAQRLKKRLDLAPLGLpGSHLALLHTRT---RAVSKCFFAIYDLAEPIAMTAMDQSKImvkRQLLLLAPEDlpEASANVLGMISSFLVMSDQTLQLFESGNCQEIAAAIAQ-- ->tr|A0A1Z2F6I6|A0A1Z2F6I6_LACCA Uncharacterized protein OS=Lactobacillus casei GN=BGL52_14505 PE=4 SV=1 -----------MTAPVTTIAAAIDAILSRLPT--VVAeaPVVKEALLKRLELAPVGIpDTGLAMIHTSS---QGVTTPYIGVFDLTSSLPLPAMDMGTIqlqRILLLLTPNPvsQETLTLLSAVSAKLVASPADLRLFEKGNYSQLYQVMTE-- ->tr|A0A174WWS3|A0A174WWS3_9CLOT Putative licABCH operon regulator OS=Hungatella hathewayi GN=licR3_2 PE=4 SV=1 ----LKPEFGIFGLEGKSREEVMENLYRCLAARGLIAteLDWKNAFRANE------VGNGIAHIQDLG---RILKNAGCYVCILKTPILWEQDI---IKVLVMIKTKrdGDKNLSLLcRIVSNWASSPEKVEHFLKSQSYDVFCGDIKS-- ->tr|A0A1Q9JT30|A0A1Q9JT30_9FIRM Uncharacterized protein OS=Anaerostipes sp. 494a GN=BHF70_06835 PE=4 SV=1 ----FSPASICFDKKYDSWENAAKAAGILLSLEGSIKESQINEVIEYLKSNGKNaiLCQGVIIAFLERE----VKRESASLIRLKELVLYTGEH--PVFYFAVFGIQDgQSINHIIYNLVSLFGNKELRTEIDKVKTPEEMFAVMREME ->tr|A0A1V6GWR2|A0A1V6GWR2_9BACT High-affinity Na(+)/H(+) antiporter NhaS3 OS=Verrucomicrobia bacterium ADurb.Bin070 GN=nhaS3_1 PE=4 SV=1 ----LPWQSVSLDLAPADQAQALSLLLALCARSGAVSalEELHAQMQARAPLIPERIGDDVALFTVES---PGVFRVALALGVSAQGVA--CACGSRCRVCVLALYPPsaaEDMARVKAALARALDAQGL-AALLAAQSSSEAREALLR-- ->tr|A0A202DG93|A0A202DG93_9BACT Uncharacterized protein OS=bacterium E08(2017) GN=BVX97_06030 PE=4 SV=1 -------RKTVIDMSKVEQEKAASLSqylipELICPDlkggtkteviqellnlldeRKLINnmRRARADIMNREKQMSSGMAHGVAIPHART---DAVSSLVCAVGVKRDGLDFGSLDGEPARIIVLTLSPKdtaAPHVRFMAMISRALNDNGR-AMVLEAREPGEIMTALLS-- ->tr|A0A0R2KVG1|A0A0R2KVG1_9LACO Uncharacterized protein OS=Pediococcus stilesii GN=IV81_GL000506 PE=4 SV=1 ---------------------------------GINAKEALASIEKRNLSGTTKIEKDFYLPHVET-NAQ------------EQGILLIHyydlnNT---KQTALVMVVNSRNPDKKLEEIMGILLNSKNINKMKHCNSNEEFRRLIQE-- ->tr|K0DBV4|K0DBV4_LEUCJ Uncharacterized protein OS=Leuconostoc carnosum (strain JB16) GN=C270_02615 PE=4 SV=1 ---------------------------------NLVQHVVEQAIIQRNQLGSVQIAPDIDLPHVVLPNLS------------YQGILLLRSW---DKLHLIMIIDNQYPSKNIITVLNFFLSDTGLKKLRTIITQQDLTYIIKE-- ->tr|A0A0R1J1X5|A0A0R1J1X5_9LACO Transcription regulator OS=Lactobacillus tucceti DSM 20183 GN=FC72_GL000956 PE=4 SV=1 -----PNNYLNLANSNGNYLSNLKIGLSEFKNRDLLSDDLIQTLINREEAGNQLIIDGvIAVPHATAN----IKFGNIFAIKLDNPVNLNNNL---INLILNVVINDqeEESRQIFSYLYKIFHNTPK-EKIKQISSYDDLLKILN--- ->tr|A0A069EWY9|A0A069EWY9_9BACL Uncharacterized protein OS=Exiguobacterium sp. AB2 GN=DI14_12620 PE=4 SV=1 --------------DQMTFDRAVQAIGLELEGRGIVDGTFTRAVLEQERTIPSGVA-DVAVPVAVIDvPRHVTREDGITLLHLNHPFDVLSITGEPvrAEMLFFVTATTEARREAFHKLMdDLLMDDETLQALAHIKSRSGLYHL----- ->tr|A0A1G1SII3|A0A1G1SII3_9BACL Uncharacterized protein OS=Exiguobacterium sp. SH31 GN=A6395_12230 PE=4 SV=1 --------------DQPTFERAVLAIGLELEGKGIVDDTFAQVIIEQEHTIPSGVT-DVAIPVAVIDvPNRISKRDGITLLHLNRPFDMRTIAGELvcAEMIFIITATTDEKKQTFHKLIdDLLMDDESLQALVHVQSRTGLYHL----- ->tr|T1KJ99|T1KJ99_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1 ----VTETKVILDVPETSVHRILEVGLLKIFGRAFDVNQFRSVLCISEDV--PKLKetfQSLTYDHngffafdqswicvtGSL---PFLSQRLTGIIRLDSPVNFGDNA-AEIRFIIMVLVPikekgTKNAFETGRTFATLFTSAEFRNNLLQAKKASDFLAVIRRR- ->tr|A0A0R3X0G3|A0A0R3X0G3_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=3 ----IKGATLLLDLEASSIEEIIHDMLEAVFTEtpghlnhaattptgisgihrhfltpnhsphgstlecedshnatnassinnsgghvhgrshtltrttgsglfatttklsalnkDELIEEAKKALLLEIKQNdlaYRRLSktiKSVSFHEnegitmdqswicalCSL---KNIQKRYLALARLAYPVNLGRSN-EGTQIILLVISPqkekkTKCEIELGRTFATILSDLEFRRQLIYAQDEEEVKALLCAR- ->tr|A0A0K0FXR3|A0A0K0FXR3_9BILA Uncharacterized protein OS=Strongyloides venezuelensis PE=4 SV=1 ----ISNASIIINEESTSLDKIINNLVCEIIFKndlknLSYVEDIREKIFNHSNYLevnkyleLLHLKnliTSAQII-genifidqkcltiyCDI---EKVSHHYVGICKLQSPTNFGTFL-ESLQYVSFILGPssskpIKTPFEVGRSVSTILSHESLRLDLEDITTKEDFISKITEY- ->tr|V4CPR9|V4CPR9_LOTGI Uncharacterized protein (Fragment) OS=Lottia gigantea GN=LOTGIDRAFT_136234 PE=4 SV=1 ----LKKTVLLLDLEKTNMDEIIDEIVNKMLKSestkNSSLEQTKSAIFTHDFGMlhfsFHQMSrtlQSTSISEgggfdydqnwvltmCSV---PSVQTRHVGIARLSSPANLGNTA-QEVYFVIVILTPtkekgTKNELEIGRTFATLFADSNLRLRLLNANTEAEFNQVLEQQ- ->tr|A8XQS1|A8XQS1_CAEBR Protein CBR-ABTS-2 OS=Caenorhabditis briggsae GN=abts-2 PE=4 SV=2 ----IQRGIIHRNMDHSHI----HTILLTLFSElssqfpreRFDLALFKNAVFSVSDRDarAPRLHqklQSY--SGtdffdvnqtwivtqlvilsfslflinrfsAQL---DGLKQSHMALATLENATNLGLEM-EEARIVVLILSPsyekhTKSAAEIARTFGTLLMNDSLRQSMTDAADDDQIRDLLTDS- ->tr|T1JUK2|T1JUK2_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=2 ------QDVMNGD------sDDKMDEiELENTGMKeetkaKLDLDEIMGSIFCEKES--RVIInriQGVLESNssptvfdqswvcilGSG---VSVKKHMIALGITEAPLNLGHGM-EQIRFILIILTPtievsagikkhTKSSYEIGRTFSTLLMHHSLRFDLLDSSK-ESIKEILTDK- ->tr|A0A1S3IGM1|A0A1S3IGM1_LINUN sodium bicarbonate transporter-like protein 11 OS=Lingula unguis GN=LOC106163546 PE=4 SV=1 ----IENAHVLLDVHESRLDDITRNMLSTTFGSsaEFDTDKLMDAIFTHDNV--HCLSktiQGTSDLGgggfdydqswvvvlGLI---PELKSQTIAICSLKHAANLGHTS-QEVKFVIYVLADesgSKEALVTGQALATIFADLRFRQELHDVHNVAGFKQLLLEH- ->tr|H9G8A5|H9G8A5_ANOCA Solute carrier family 4 member 11 OS=Anolis carolinensis GN=SLC4A11 PE=4 SV=1 ----LARASIILDETATSLDDVLREMLKHFAEDsdnaepscnfdki-------MSTLFTDSGTPregnVHLLSdtiQGVTATVtgvqyqqswlcimTTL---TTTEKKHLYSALLTPKGTQGGSH-AHIKVMILQIKPqnimlYNKltekAVQYTVTLCSIYYIYKFRTKTINFKVVQGIKSMMKHK- ->tr|A0A1Z8M876|A0A1Z8M876_9PLAN Uncharacterized protein OS=Rhodopirellula sp. TMED11 GN=CBB71_15795 PE=4 SV=1 ----ISQGSCLLNLDATSMDQVVESSIDILIQSg--RLPEYQRELVIEGVHQrEQMVPtaiGSAS---avphFYD---DRIEKPLMVFVRLKRGVNFGAPDGIPTRYVFLLIGPtdqa-ASHLDSLASIARMMSDNVCQFELTYAESVEDVLGVIERH- ->tr|A0A1U9YRZ3|A0A1U9YRZ3_9BACL Uncharacterized protein OS=Paenibacillus larvae subsp. pulvifaciens GN=B5S25_17975 PE=4 SV=1 -----NSEHTFQLSRISSLDEALNLLAAPLLQKNYIQASYMAQIRKEiVDEQKWYfIYPKVLLLHTDYR--YGSFKPGVSVLYTASGLIMKDEPFLEAELIILLSTDEKmTHVPLLFDLDKLMQS-SFLSELAKGVLMETAFYHA---- ->tr|A0A0Q1ACL1|A0A0Q1ACL1_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_01185 PE=4 SV=1 ------------------------------------------------------MGGGIAFPHGRI---NLIKTPLVAVGLSpKKGIPFPSKSGSRkisTYLIFMLLLPssdypvniagkSKQYINAISSVAKFLRTIKSKKLVKSFKSEPDFLNFVEKY- ->tr|A0A0C2D533|A0A0C2D533_9DELT Sulfate transporter family protein in cluster with carbonic anhydrase OS=Enhygromyxa salina GN=DB30_05862 PE=4 SV=1 ----IPAENIELRSSAATLDEVIELAAPRLASLvGLDTEPVLEALSAA-SDGHVPLGDGVSLPHAAI---EGIERSVVVVVTTTTPLTIGDDQ---TDIFFVLLSPagdTAEHLRSLAHIGRMCHRSPLLDELRRAPKPE---------- ->tr|A0A0R2HU27|A0A0R2HU27_9ACTN Uncharacterized protein OS=Atopobium minutum GN=IV72_GL000271 PE=4 SV=1 -----KENYVALQTKGLSYEATLTKGLDMLVSCGRMSKEEATATLARELQADRLEFNGVAVPHCVTK--TPSHSFRLFAICPTTAV--PTPQEAIKLILIVFASKHqDDKNTIFSYLYSTLSSQASIE------------------- ->tr|A0A133XVQ3|A0A133XVQ3_9ACTN HTH domain protein OS=Atopobium deltae GN=HMPREF3192_00640 PE=4 SV=1 -----EQNFCRLAVVgdadvadcvaavglNASYEQLLKRGLDMFVQRECMSKTEARKVLDREQSSDRLYFKGVAIPHSVTE--TYASQFRLFAIAPDRAVFadaNTAPDKPISLILVVLASQHlQDKNSIFSYLYTVLNTQAQIQ------------------- ->tr|A0A1Y4BGW2|A0A1Y4BGW2_9ACTN Uncharacterized protein OS=Olsenella sp. An293 GN=B5F85_03225 PE=4 SV=1 -----EESYFHLSVEpGQVYLSVLEDVLGRLVDEHRITADEADLIRQRERAGKRLNLGGIAFPHAITP--VESDEFRLAVACLDEPV--TDTDDRIELVIVVLASQSqADKSSIFTYLLSVIEDARARG------------------- ->tr|K4IJV5|K4IJV5_BIFAP Putative PTS IIA-like protein OS=Bifidobacterium asteroides (strain PRL2011) GN=BAST_0019 PE=4 SV=1 ----------------ESMHALFVCICRHLQSKGIIRsvDLLAKELLAREVSGSTVIADHLANPHAQGP---FVDECVLFYLRLSRPVpKWDGLH--EVSRVLLTLIPQNpsmEDLQYLRDLYRRMGGERVLDLL----------------- ->tr|A0A0Q0WEC6|A0A0Q0WEC6_9DELT Uncharacterized protein OS=Desulfuromonas sp. SDB GN=APR63_02155 PE=4 SV=1 --DILKEQNITICQEKMDYPQVIQCLIDLVDIDQDQQQQIVNFINSNEKLTSSTLGKGVMLFKAWP---VQIQSTHCSLLIFPQGCEIEAFDDQIITICGLIAAPqekEQQYHQLLISWLRMLNESSLRDDFIECDTPQEVINLIREEE ->tr|A0A1G3Q9J7|A0A1G3Q9J7_9SPIR F0F1 ATP synthase subunit alpha OS=Spirochaetes bacterium GWF1_41_5 GN=A2096_16900 PE=4 SV=1 ----LAEKCLIIDYkGKPSIRNVFKSASAALAEslQNTNEKEVLQKLLEREQSSSTALSEFMALPHIIT---GGTSQFQMVMVRAGAGIKFTDQH-PSVKALFFLAGSmdqRHFHLVVISALAQIVQHPSFESSWTQASGSSELRKIVLS-- ->tr|A0A0A2W1K0|A0A0A2W1K0_BEABA Phosphoenolpyruvate-protein phosphotransferase OS=Beauveria bassiana D1-5 GN=BBAD15_g233 PE=4 SV=1 ------PDVVFAekivGDGIAIkptGNKMVAPVDGTIGKIFETNHAFsiESDSGIE-----LFVHFGIDTVELKGegfkriaEEGQRVKKGDVVIE-FDLPLleekakstltsVVISNMDE-IKELIKL-------------------------------------------- ->tr|A0A1Y4CF67|A0A1Y4CF67_9ACTN Uncharacterized protein OS=Olsenella sp. An285 GN=B5F79_09945 PE=4 SV=1 -LDLLGERCFGVCDEVEGMDELILLGGGLLHKAGLCDEEYPRQMVSAAHCFGPLttilIAPGIIMPHAGIS--DHVRGTGFSFVRIRRPIYVNGKE---VFCALSLCTRDKlVNQRAIQQVGMLLSRSDFIDRVRAVGTYEEFAETVSQ-- ->tr|D6XZQ1|D6XZQ1_BACIE Transcriptional antiterminator, BglG OS=Bacillus selenitireducens (strain ATCC 700615 / DSM 15326 / MLS10) GN=Bsel_0902 PE=4 SV ---------VSAAKGPDRLEQIMDEGISLLEDDGLVTEGFYDDIHHTvfQKKYLYEIIPGLLFIHGNS---DHVLKAGFSLVQLKEPYVVEGKL--HSTAVLFMATPDkDAHIPQLQYLYQIFMNERKVKDLLDWTT------------ ->tr|B9Y4E8|B9Y4E8_9FIRM PRD domain protein OS=Holdemania filiformis DSM 12042 GN=HOLDEFILI_00679 PE=4 SV=1 ----FSPRYFNGSLKGSVRDEVFREVAKAFDNWKEILAM----FWEAEHILSHETTKGVVFLHTLKP----LPESFIYIGFLKKPIIWNKLW---AQAVIFVNINGDlDSLRLGYDFISEMINDPREPFSGKITEYEDLIEVLSKN- ->tr|H1BMU6|H1BMU6_9FIRM Uncharacterized protein OS=Eubacterium sp. 3_1_31 GN=HMPREF0984_01703 PE=4 SV=1 ----LLPSLYQEGLLCKNKQDVYKELEKLLAaMWGEAEATK---LVNGIYHLGNEVGNDIICLHSRYD----YHTPFIAFLSLKNHMLWEKQH---VRYIFFMNMNAEsDKemVHHMYHLISNWAdVKTRITYYAKNQDYQELIESLDNS- ->tr|N9VDC9|N9VDC9_CLOIN Uncharacterized protein OS=[Clostridium] innocuum 2959 GN=HMPREF1094_00865 PE=4 SV=1 ----IRKEYFFTNLECNTQEDVLISLANLLAsEMGQGISNS---IMNGICLSFSEVGNGCVILHTLYD----LAIPCVAIMLLKAPVLWNHSY---ISTVVFCNVSVLEYslIEQIYQKISQWCeKDHRYI-----KNYEQLIKSFE--- ->tr|A0A1T5MMD7|A0A1T5MMD7_9CLOT Transcriptional antiterminator OS=Maledivibacter halophilus GN=SAMN02194393_05030 PE=4 SV=1 ----FCKDYLITGIKGNSRKEILKQIYTKLIeL--KVAKRK---ELSKMPFVSHEIGNRVVNLQDLYK----VCHkEVCLIVVLEKPILWEKSI---VEVFFLIKTKKDgDKdlF-ILCDLFSKFAsDKEKIKDLIDKKDYESFMKDILEY- ->tr|A0A0F4M0J2|A0A0F4M0J2_9LACO PTS IIA domain transcriptional regulator OS=Lactobacillus mellifer GN=JG30_00460 PE=4 SV=1 -LRLLHPENTIFTSQFLNWETAYLMIGKLLQKHAYIKHSYWTAAINNIVSYGPYivLRDNLAIAHAQNN--HSVLADTIGLVYAQKGIGFDSKN--KVQFLLFVALQsDDDYLAVINAILNVYDNYNFFETIQD--------------- ->tr|A0A0L8ATL5|A0A0L8ATL5_9BURK PTS mannose transporter subunit IIC OS=Limnohabitans planktonicus II-D5 GN=H663_19215 PE=3 SV=1 -------------------------------------------MGASRGQLVIMAPLsGVLVSLDSVP--DPVFAQ----KLVGDGVSIDPTSD-------VLLAPVAGTITQLHKS------------------------------ ->tr|A0A235IIU5|A0A235IIU5_9NOSO Phosphoenolpyruvate--protein phosphotransferase OS=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A GN=ptsP PE=4 SV=1 -------------------------------------------LGVRELAAQMVQGQvPIAVAAGIEDPE------------NPLG---TDPIQVYE--AIASVFSDDGVLVLMDLG------------------------------ ->tr|A0A1F6GF09|A0A1F6GF09_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_03755 PE=4 SV=1 --------------------------------------KLLAALDQREAEFSSLIGYQISLPHVYC---KETREPLMIVAKAMGHLASPVGG-EPISTIFMIISPKDQpevHLEQISKVAKFISKEKNRFALAAAKDEAELFYALERG- ->tr|A0A183V6W6|A0A183V6W6_TOXCA Uncharacterized protein OS=Toxocara canis PE=4 SV=1 ----LNKSVLLLDLQETSLEEIFAKIIH---EMDIQEPEFtseqvrsvlftqdagnqfhiLSRTVQSICTTGtiggsfd---ydQTWICALCMLN----TVQHRHVAIARLSHPTNLGRTM-QDLRFIIIVIAPsratwTL------------GSDSSWRKPLSSS---GELPSLFIN-- ->tr|A0A1V9XTB9|A0A1V9XTB9_9ACAR Anion exchange protein-like (Fragment) OS=Tropilaelaps mercedesae GN=BIW11_07582 PE=4 SV=1 ----L---SIILDSQEMELVAIVK---QLLGKMFNENTALitatleniffce---TDNAISDLLmsasaqqsKGIvfdSSYLCIPCSMP----TdFAKRFVGVCRLATAVNFGTSA-DRVRFIVVVVTPvnvkaTKTSLEVMRTFSTLLSNPWIRHRLTTEArTENDLKAILTD-- ->tr|F6IXS1|F6IXS1_LACPE Transcription regulator OS=Lactobacillus pentosus MP-10 GN=LPE_02508 PE=4 SV=1 ----LQANHFYHVSGKHqNVSQVLKAGLVNFSDRGLLTSEQSVSLVAREEAGNQLVLNHVSLPHASA---KLSETYKIFAITFDGVLEIDNT---PIYVILIVLANEkqTDSGQIFGYLYTKLKQLND-TQLQNIDDYQTLIKYLG--- ->tr|A0A0R2N289|A0A0R2N289_9LACO Frv operon regulatory protein OS=Lactobacillus saniviri JCM 17471 = DSM 24301 GN=IV56_GL000437 PE=4 SV=1 ----LPPNHFVSLPLIKRFDVALKKGLDIFVERQLLTAEDEKAIIDREAAGNQLILNHVSLPHTTS---THFAEYGIFAIKLANEVTVADT---TVQLLVVVLANTsqVERNTIFSYFYQTLRKQPL-KSINAAHEYEDVLSLLG--- ->tr|A0A1A8XE12|A0A1A8XE12_9PROT Multiphosphoryl transfer protein OS=Candidatus Accumulibacter sp. S1 GN=fruB(HI PE=4 SV=1 -MMPTVATRLEIVAPlsgvlVPLESVPDPVFAQKM------------------------VGDGVSLDPTTGDLLAPVAGTVTQLHKAhhALTITTGQ--GIEVLLHIGID------------------------------------------- ->tr|H7F4P9|H7F4P9_9LIST Transcriptional antiterminator, BglG OS=Listeria fleischmannii subsp. coloradonensis GN=KKC_06027 PE=4 SV=1 -----------GSDMTRNKEDNLRSFSQSIANKkpDLSSDKIFKKLSSLEARQKIISgGTNSAYFLVN-D---NVQTASTHIFTLNHSIDFQIEDGLKspVSTVMVFMLPyklNAELLEITTYLLTVLTEDDAAILLAESGDETKIISLFTTY- ->tr|A0A0R2I9X9|A0A0R2I9X9_CARML Uncharacterized protein OS=Carnobacterium maltaromaticum DSM 20342 GN=IV70_GL000323 PE=4 SV=1 -----------IQQVVKNIEEVSEVITKVIYQNqpKSRMDYLINALTVEEQQGGVGIpGTTLALFFIRNE---MISRPLFQIFTLRNHVRLQATDKTEieISTVLVLLAPeklATGSIDILSRLSTLMIESDEVIQSFESGDRNKITSLVIQK- ->tr|A0A1E5G819|A0A1E5G819_9ENTE Transcriptional regulator OS=Enterococcus plantarum GN=BCR22_07635 PE=4 SV=1 -----------LNENLGTMEDAVRVICTQLLEKapEIDVEALVSTFLYDGNWKAFGLpGTKIGLFHARNE---SIKEPVFQLFSLEQSLSIETMNHTKmpIDRIVLLVVPekfSQEGLEVISYISTLFVDDQDMIQQVEDGVKEEVTTYIAQK- ->tr|A0A1S7FSL8|A0A1S7FSL8_9LIST Transcriptional regulator OS=Listeria weihenstephanensis GN=UE46_04490 PE=4 SV=1 -----------MEETQHNLEDTLRAVCMAMFEQerDIQVEILLKSLLEREKWSGFGIpETKLALFHVRNE---FVHQPVFQIFSLQDAVDVPAMGGGNvaATTLLVLLAPeklAPQGLEVMSFISAMAIENEGTTRLLESGNGAEITTFVIGK- ->tr|B3S4Z9|B3S4Z9_TRIAD Putative uncharacterized protein OS=Trichoplax adhaerens GN=TRIADDRAFT_59409 PE=4 SV=1 ----LTESTILLDIAQTDLESIVEKMLTKLFDKEQLQCSMSEAVISllskdievckfRNLMQGTEYseGGGIAITQQYLVafcQLQTLTGRHVAIGRLKEPTNLGPTS-QEVNFIILILTStkekgTKNAVEVARTFATVFADEEFRQILMDATNDEEFKKFLNE-- ->tr|A0A087CGX0|A0A087CGX0_9BIFI PTS system, IIA component OS=Bifidobacterium psychraerophilum GN=BPSY_1370 PE=4 SV=1 ------------NWQVHDKAALLSRVSQYLLDERMIVdsDAITWALTTREDLGNDLVAPNVAIPHAQH---AAVEHAVMLMVKLRHPLlDWCPGA-DVDRYVFSLIPttPSARDAGELKEFYTDIADDQVMDRL-SLGDQREIRTIFASRR ->tr|A0A0E2XEV7|A0A0E2XEV7_OENOE Uncharacterized protein OS=Oenococcus oeni GN=EL27_04075 PE=4 SV=1 --LLVGNNVIFINNHTSDFFSVLISGLKKLIADKAISKNEGQMILEREREGNQLLINGVSIPHVTIPN-TSDNYRILAIVPKEKPILNNENV--YLLLIVLVGQMQIDKSSIFSYLFHLLKNKNY-QSIIDLRNRKDVIKLLTD-- ->tr|U3JVM2|U3JVM2_FICAL Uncharacterized protein OS=Ficedula albicollis GN=SLC4A11 PE=4 SV=1 ----LARASIILDETATSLDDVLREMLKHFAEDPEnmepscnfekiMSTLFTDSGTPREGngthdvsestgmnvqtgpshlkfhllsdtiqgvtATVTGVQYQQSWLCIICT-IKSLQRRHVCISRLERPQNWGENS-CEVRFVILVLAPpkmksTKTATEVGRTFATMFSDITFRQKLLETKTEEEFKEALVHQR ->tr|A0A0P6IPS9|A0A0P6IPS9_9CRUS Sodium bicarbonate transporter protein 11 OS=Daphnia magna PE=4 SV=1 ----LEQCVLLLDDEAAQTSTPV-DLVDLLLGKMDlpvavveeaKTILVTHDIV----pslaktiqatyStrdNVNIFDYDESWLCTMGD-IPSLAQRRIAIMRLKHPTNMGETC-HDVQLFVLILCPgkekgTKNGLETSRTFATLLADVNLRRQLLEVTNEEEFKELVLKRA ->tr|A0A183BP25|A0A183BP25_GLOPA Uncharacterized protein OS=Globodera pallida PE=4 SV=1 ----LDRCAILLHVTETLLEDVVLKMVEEKPEYHGpgegvaiendrlefvsfrqiCDKLFVSIDT----rtsltstefalrvhlqgvlTdEQLGVVEDQRWLVLYCS-IDRLSRPRVSFARLAKPTNFGNAN-L------------------------------------------------WPKS ->tr|R7Q0Y4|R7Q0Y4_CHOCR Putative sodium bicarbonate cotransporter OS=Chondrus crispus GN=CHC_T00008463001 PE=4 SV=1 ----AQTAPLLLNLPPAPPRRILRLLLNHLVDAGQipataineaVHALFGEPNSSAPNnscaqnsedafdtlhqrppglpLdadnnsrdpqtsrdtnfrhpadqLPGHWHKnvlGSGFIipfARLNA-LNTCDRCVVAIARLTSSCNLGVANGSLVRFVVLVLGPvkelkeTKTPFEIARTLSAMFQDDQFYSDARLASSDGHFRDAIRKYL ->tr|A0A0R2GUD8|A0A0R2GUD8_9LACO Uncharacterized protein OS=Lactobacillus acetotolerans DSM 20749 = JCM 3825 GN=FC77_GL000643 PE=4 SV=1 -----------LKHNSSRIEDVIKQCLDNCDSDIVKDkKIVADKLFKRIKLTPVGIPGsNLALFHTSS---KGISRCSFTIFDLENDLTLQAMDHIDiqVKRILLMLGPamlSTAEQKVMSLVSSMIITNDDNLHLFSVGQQEQIKNAIAVQ- ->tr|A0A0R1ME33|A0A0R1ME33_9LACO Transcription regulator OS=Lactobacillus capillatus DSM 19910 GN=FC81_GL000811 PE=4 SV=1 -----------LNNNNEKLAELLVQVLAKVPTAVVKEpQQVVHEMLKRVKAAPVGIPNaSISLVHATD---KSVLKPFFSVYELRAPLTMKAMDQTPiqVKRILLMIGPapmTDFQNNLMGTISGAIVMNNRYTAIFEKGNVDKIKNLIAAQ- ->tr|A0A0L7Y262|A0A0L7Y262_LACPN Mannitol operon activator BglG family OS=Lactobacillus plantarum GN=AVR82_02345 PE=4 SV=1 -----------IRNDDETVAEMLVKITRHIDSNLIHDpLEVAGRLLHRLGLAPVGIPNtNLALVHTLS---QEVTAPYCAIFELDQPLPFKSMDNQSirLQRIVLMLGPaniSDFENRLMGKLSALVIESQANTQTFMTGDRQQLYQLISKA- ->tr|A0A222W5Y7|A0A222W5Y7_9LACO Uncharacterized protein OS=Lactobacillus agilis GN=BEN83_09315 PE=4 SV=1 -----------VANQGSDLGASIEETLAHIPGEIINDkEKVTLALLRRINLAPIGIPDtNLALLHTSD---AGVNQCYFGIYELAHPIKMLGMDREEmqVSRYTLMVAPkevTDLEQKVLGIISSSIVMNSENTNVFETGTSEAVQELLANQ- ->tr|A0A139TKJ4|A0A139TKJ4_9FIRM PRD domain protein OS=Candidatus Stoquefichus sp. KLE1796 GN=HMPREF3037_00318 PE=4 SV=1 --DFIKPKNILLNSSMESKTEVLQYISKVFQL-------SFSELDLKENVGNMAMEGHIAIPQMIG----YSDIVEEMLITFNKPIIWDH---EFIQCVLFVSLPKRfflRYQGYYSLLQKLVMDQEAIEKILSFQKTKEVEEFLSRYH ->tr|G9R068|G9R068_9FIRM Uncharacterized protein OS=Coprobacillus sp. 3_3_56FAA GN=HMPREF1021_01312 PE=4 SV=1 --DFLKKEDTYFI-DCETKDDVISYIFEHESV-------SFETFYHTNPLIGFETSLQTVIHYMPI----YNQKSSINAYLLSKPIVWKN---KLVKIIFVLKLGID-SEQLLQSLQEFFFQKECMDTFLNNM--------ILEEG ->tr|A0A1C1ZYI2|A0A1C1ZYI2_LACRE Uncharacterized protein OS=Lactobacillus reuteri GN=BBP13_12895 PE=4 SV=1 --SIFDNLRIYRESSQIDHERIIAGMVAAAEREALVSnkEAIVQTLKEREEQGGLGIpETSMALFHCRHE---GVGKLLFQISHLHYPCQVKGMDGKMmeVRNLLLMLAPENltiREQEILSLISTNLIEDKEAMMIFSSSNEEMIRKNLED-- ->tr|A0A099YCT2|A0A099YCT2_9LACO Uncharacterized protein OS=Lactobacillus mucosae GN=LX03_02675 PE=4 SV=1 -----------------NRDEWLKHVAGIIPDFVDDSTPLIHALSNREEIGSTRLAEKLVMPHVVMP---GIADSYLIVSQLESPVEWFDNHSVDTGTFLIV----EGNDEAISNFVVHMADDSFVERLCERGIEKKTIESLLKE- ->tr|A0A0R1V5S9|A0A0R1V5S9_9LACO Uncharacterized protein OS=Lactobacillus gastricus DSM 16045 GN=FC60_GL000937 PE=4 SV=1 --------------QVKDYQDWLYQLGHLMTKEPDLQNELIQQLVGREQVGSTIIDPGIIMPHIINE---NLFDHVVIVSHLQTPLKLADQN-VTTAVILLM----RTIDTQIDSFMKALISDDHLQQLKE--------------- ->tr|A0A1M6NUR2|A0A1M6NUR2_9FIRM Mannitol operon transcriptional antiterminator OS=Anaerocolumna jejuensis DSM 15929 GN=SAMN02745136_01459 PE=4 SV=1 -LQIIDNFLFIEQVAAENEEMLSHFVSRSLAVSGADRFQMEKNMENKEQKGSAILsRKRMVLYHLRS---EAVREPGMAVLRLKSSIGSIGKDGniQKADTFIFLSMPvdtEGCVLELINEITRKIISSDFSLTLKQSGREEIIIEL----- ->tr|A0A1T4KXV1|A0A1T4KXV1_9FIRM Mannitol operon transcriptional antiterminator OS=Garciella nitratireducens DSM 15102 GN=SAMN02745973_00716 PE=4 SV=1 -LQILNNFFLMEYEKFENIYQLIDTLSYKISEKEENAIQIKHDLIEREKYGGTILtGFHAILLHCRT---SGVKQLFFGLIRIKKSLICSNREEke-PIELAIIMLIPennNQFQREIMSFISSKIIEeAGLLQDLKQAQQEKVYTRL----- ->tr|A0A0H3YIY0|A0A0H3YIY0_SCHMD Slc4a-9 (Fragment) OS=Schmidtea mediterranea GN=slc4a-9 PE=2 SV=1 ---FLKEATIILDMEEFQPIKIVEKILYKIISDKEIEigQSHVKEMIAEAKealftqveisnysyqrltrtikgillnpVDGTTFNQPWICAMCSF---SSITKRFISITRLKYPVNFGRNG-IRVNFVILVLTPKkekesKSDFELSRTFATLFSSIEYRNEFMNTDSPDVFRQYLKSE- ->tr|A0A1S9C1Q1|A0A1S9C1Q1_9FIRM Uncharacterized protein OS=Epulopiscium sp. AS2M-Bin002 GN=ATN32_03235 PE=4 SV=1 --NLINNIFFYKSNDITSKLEIIQKISILLGETEADILAIQKGLQERELISSTYIrESNVYLFHCKT---SGVTHSKFGFFKLTNP--FQNKSGYWVCGGILLLIPEnstKFQIDIFTMISKSLTDERIMEKLITVESKVEVVSVIESS- ->tr|A0A1C5TZU9|A0A1C5TZU9_9FIRM Probable licABCH operon regulator OS=uncultured Eubacterium sp. GN=licR_3 PE=4 SV=1 ---LLDHIRIGRAPVLQERQEILAYAASLFSDTPEMESHFYEIMKKRDQIADTYMkPFHALLLHGKS---PDIMHPCFGYVHLEPPIYENAR---IILGAIVTFIPEndpdQVSAPIVSEIIGALMEQPELLKALREDDDERFTLLLE--- ->tr|A0A1Q6MYZ8|A0A1Q6MYZ8_9FIRM PRD domain protein (Fragment) OS=Clostridiales bacterium Nov_37_41 GN=BHV95_06040 PE=4 SV=1 ---VLDNIKISTGENIKNKKQLIEYAGELFARNETTATEITFALNKRENIASTFIpSMNALFLHCET---KGIRHCRFGFVYLNDEIIEDGK---PIKGAILMLVPQgdgsKVYREVMSEISGALAEKDQIITYLFDK------------- ->tr|A0A1Q6L9Z6|A0A1Q6L9Z6_9FIRM Uncharacterized protein OS=Clostridiales bacterium 36_14 GN=BHV87_05315 PE=4 SV=1 --DLLDNASWIESSNCSDFFDALKLLYNELTKELPLDVSFLASIMQRESILTFAHHPHVSFVYQIG----DYEKTSACAMTLDHRIKYHDN---KIRIIVLVAIAKNDSNFIFKMLNELFNSDFNLNDLKFLKTKKEILNALKTY- ->tr|A0A160PSR3|A0A160PSR3_CORGT Uncharacterized protein OS=Corynebacterium glutamicum GN=N24_3085 PE=4 SV=1 ------------------KDKSLKELVDAAVRFDPTStEDILEKIQHRDQIGSTEVAPGFFIPHVVT---DSVPRIQLVLGTEGE-----------VTWLLVLMPSNavPESKRALSLLMRQLAYEEEVSRIRSFSSTEQFQHYLAVIE ->tr|A0A1T4N5D5|A0A1T4N5D5_9ENTE Lichenan operon transcriptional antiterminator OS=Pilibacter termitis GN=SAMN02745116_01312 PE=4 SV=1 --------------EGISYEENLERCIECLSNQGILDEQFYERLSEREKLRTTVEP-PFAFPHTIN---SKSEQLVLIFGKSSEGLESHFG---KVHFFLLLCIPeemdeekERVLLQVYEVVFRLFRRYILQNGKKQLPTIDELKDLVEAS- ->tr|A0A0R2BSI9|A0A0R2BSI9_9LACO Uncharacterized protein OS=Lactobacillus coleohominis DSM 14060 GN=FC35_GL001757 PE=4 SV=1 -------------VDVKNYSGWRKLVIKKLMLSDKLSADLLVQLQERDRLGSIQVDEHVIMPHVVS---NKLPKSWLIISQVDRPIKYGTSNDITTGIYIFSRPKDSS----ISSSVDCLADESVMKALQNPKlSYQQLMELLR--- ->tr|A0A1V6EQF1|A0A1V6EQF1_9BACT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Candidatus Hydrogenedentes bacterium ADurb.Bin101 GN=B -------------DQAQPLDMALQTMAARLCDRDAPRNDILELLRQAAANYPVELVPGIVMLHAHS---DSVGSTTILVGAGGAGWSFPGVE-TPAGTILALISPrsksPEIHLAALSQLARACREGEFTRAIREPMSAEDIAGVLK--- ->tr|A0A086BPF9|A0A086BPF9_9BIFI Putative phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bifidobacterium bombi DSM 19703 GN=BBOMB_1226 -----------FLKDCTDLDRALHVLSEYVCRAGLGKeaSRIENDLGSRCRAGDVMLSHGLVNPHAQS---SNVLVSTMIYVKFAKPLRANAVyastvESGFSRMLLTMLSTSptQEEVREVCGWYRSMADDEILALLAN-GTQQEIRRLLLEEG ->tr|A0A1C4AA63|A0A1C4AA63_9BIFI Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=Bifidobacterium bohemicum GN=GA0061078_0836 PE=4 SV=1 -----------SGIDIVDKAGLLMWVASYADRRGVTAdgRRLARVLEDRENAGDTRLAIGLANPHAQD---RVVNSATLLFVKLLRPLADWRPGDCIDRFLFTLLPERvaFNEAARIKAFYRLIANETAMNVLRV-GDQEEIQSILPTER ->tr|A0A1D4SJJ3|A0A1D4SJJ3_STAAU PTS system mannitol (Cryptic)-specific transporter subunit IIA OS=Staphylococcus aureus GN=SAMEA1708664_00507 PE=4 SV=1 ------------------------YIADYLYQCDAINdpTSFAELLEQRLIDNPGWIlsPYPVAIPHLRD---NMIKHPMVLITVLEEPLILPSiqNDNQTIKYMISMFIPDNDFMASLvSDLSEFLSLKlESIDTFME--NPQELETLLRNK- ->tr|U2QJ27|U2QJ27_9BACL HTH domain protein OS=Gemella bergeriae ATCC 700627 GN=HMPREF1983_01334 PE=4 SV=1 -----NVYVSELFTADTDIKNMLVDIFKKVNLKSGNQQNIIENLIGRHEKSSVVIpKTKLALFHTLE---NSLTEPFVIICNLKNEIELINVSLNKemVRTFFIMVSPNeERYTNFLGQISIAILNDEVLIKAINSKNRE---------- ->tr|A0A1M6VIK5|A0A1M6VIK5_9FIRM Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 OS=[Clostridium] lactatifermentans DSM 14214 GN=SAMN02745138_02381 PE=4 SV=1 ---LLDHVQLLVLPYAQDKQELLYVASGMFTETKEARELIADSLAKREQISSTYIrDFQMMLLHCKT---GGVKHCCFGYIRLKRPLFQSEG---VIEGAIVMLVPkegDSLEAGLMSEISSGLLEDEAFFSAVQKKGRISIIESLEKR- ->tr|A0A200IXP4|A0A200IXP4_ENTFC Transcriptional antiterminator bglG OS=Enterococcus faecium GN=A5806_002131 PE=4 SV=1 ---LLGRFFIQELDNPETISETIRSLFPYFPEGLVTDeEVVHRRLLKRYEQAPIGIpHTNMGLFHASS---SLISKPIFCIFNLKHPLTIEGMDRQPVdlsRMLVMLAPSPiqEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLA--- ->tr|A0A116RD67|A0A116RD67_STRSU Mannitol operon transcriptional antiterminator OS=Streptococcus suis GN=mtlR PE=4 SV=1 -------------GQQTSFDEAVVATVGELEH--VADrAYLADKLLTRFSVSPLAIpQTNLALIHTQS---SQVRHSQFVIVELENSVSALSMNNQQeaVQRILVMLTPlgvEAEVRELMTAISQSIIENKLYTEIYRTGNQEIIYQLLNS-- ->tr|V6Z174|V6Z174_STRAG Phosphotransferase OS=Streptococcus agalactiae LMG 14747 GN=SAG0136_05145 PE=4 SV=1 -------------DNAKHFDQSVATIVAQLPG--ISDtNYLTQKLIQRFHQSPMAIpDTGLMLLHTQS---HTVETSGFYICDLTKTISAVSMNQQTenVSRVLIMLTKtseNDSVRDLMTAIGQSIIENHLYTEIYKTGNKAIIYQLLNQ-- ->tr|S7TXT7|S7TXT7_DESML ATPase, P-type (Transporting), HAD superfamily, subfamily IC OS=Desulfococcus multivorans DSM 2059 GN=dsmv_1861 PE=4 SV=1 ----LQPDHVHLDVRG-ALEPVLRRMAGGLPH----GEELLERLQPLLEDMDTLLlmpSDDVVLPHFRM---AGLEEPQLALGISRRGIACRGK---SPRIILFLVSPeedPSGHLKLLQRVSALLPELAKR--LAAVRSPSQAIRILAEGE ->tr|A0A0T6A6K4|A0A0T6A6K4_9BACT ATPase P OS=candidate division NC10 bacterium CSP1-5 GN=XU15_C0003G0049 PE=4 SV=1 ----LEADLILLDAEQGsgeFLHPlaERIVAAREVPQ----RDDFLAEV-------SkDLVenrIEDVSLGHALL---DEFDRMAI-------AIAISGtS---FQAITILVLSPlkeSGTHFQVVSKLEGMLQERAFREALRSACTPEAVIQVFER-E diff --git a/esm/examples/hhblits_uniclust_2017_10_1xcr_1_A.a3m b/esm/examples/hhblits_uniclust_2017_10_1xcr_1_A.a3m deleted file mode 100644 index db80f9f..0000000 --- a/esm/examples/hhblits_uniclust_2017_10_1xcr_1_A.a3m +++ /dev/null @@ -1,502 +0,0 @@ ->1xcr_1_A -CAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD ->tr|T1J6L6|T1J6L6_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1 ---KLELYQPEANELRSVLEKGLKNSFEEASVQIIDCPNLKKEPFNLAAKGICGRPTLIDVGGVRNLQPVPLRNKIYNLDKLTQIAHNPEAFLMGAGGGPFHITSVNCEVSILTRWDphKNSS--FLQCFLvfrtlSRVrilssltsvlisrchkdrpqmpdpgysalgprtawleilhiiaglkfmanirtsatghgrnlsyiarlDP-VNEYKLl--QMPE--NRECGLMLNALVCEGKEGKVMQVKAKKRTQDTNFITAMRETLKVAYGDKPIGFGGVFLLQSGNAKLHIMP-DFPIYPLNDDATVNSWLKFYDMHAPLACLSTFVTNDPlNMDLRIEHTHCYSDHGQGGHYHHDTTPDTAEYLGYFVLCNTLYRIDKPAMLHRRK-- ->tr|A0A0P5YSQ6|A0A0P5YSQ6_9CRUS Ester hydrolase OS=Daphnia magna PE=4 SV=1 ---NCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTVQRDRTYDLADLPGLMNVKDgtILMIGAGAGPWQHLNTNCEMMTNLSLTleEGKSNIVNGTRLATVdpagqrmlhvvxxxxxxxxxxxxxnivngtrlatvDP-AGQRMLHVVPPE--QTRCSLLNNLLISRGQPStPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSVHGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSETHRVGRD ->tr|A0A177FAU3|A0A177FAU3_9EURO Uncharacterized protein OS=Fonsecaea monophora GN=AYO21_04498 PE=4 SV=1 ---KVELAPPSLSALAQGIVSGLCSNFSISDCSVANPPDLTAAPYHLAGPGLSGSPRIVDVGGPPNLSPTPNMTKKYDLTAIAGQVGmSPa-tGFMLGAGAGPFYVLGQNSELMPNFAYGtaAG-ggeDVVRNRTHY---akiT-PSD----tVCCAQIPqASTGFAFMCNLFCSDGVPGQCLHVTARSRTGPLNFTESIQHGLQATFGDk-LISLGGVFLIKKGKARLHVMP-DFPTQPFNSRADVERWLRYFDMsfdagggadtgakdkhaegggsggggdgdgDGPLVCLSVLHSGDDaGLGLRMEHTHCFTvpsspssadadanlnkdrETTKGGHYHYDLdeTMDEIEYEGWFNVAETLYRVDQPGGSTA---- ->tr|B4LCD4|B4LCD4_DROVI Uncharacterized protein OS=Drosophila virilis GN=Dvir\GJ12897 PE=4 SV=1 ---EKPLHVPTLEELQQVIQGALRKNFATASVQVGDCPDLKAPQYGLVESGLGGRATLLEVGGPPHLLPLVQRDKLYNIKEIARRIQgA-GkIFAVGAGAGPYPIRSSNCEGIYNLSVSaSD--ELTNGSYT---atvRGEQEECVLe-RIPST--EARCALLLNLYLSRGEAGPVLKISAKQRKGELNFIECIRKGLEEHYGDRVVGLGGIFVIKKGAAHQHVMR-DFSKTPIHTDAEVNEWLKFYDMPAQLNALGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDTVEYEAYLNVAERVVRVDKPLATHKVGRD ->tr|A0A183SZ16|A0A183SZ16_SCHSO Uncharacterized protein OS=Schistocephalus solidus PE=4 SV=1 ---VLRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISASKlQT-GQLIGAGAGPFFTAGKNCEammgnrdpnelfntstnyidwsyyylkgsrqlashelkstrdfqmftlMAAIVKVAenD---VRSNNTLH---gvyNKSED------KPGVLkaTDNNFALLGHFLATEGNPGKVLAVDVSVRAKDGSIYTFLREALTAKFGNesAPVALGGAFVLDNSKGRFHVMP-DFPKKPVDSPAKISSWLKFYEMSPPVMGVGTIVSHDPvGYFLSTlEFVDCLLdrfn---NSSS-YGE--P---EFQTVLIVTPFFMRGNN---------- ->tr|A0A158R7K1|A0A158R7K1_TAEAS Uncharacterized protein OS=Taenia asiatica PE=4 SV=1 ---NHSVHEVQKEELVEVLREGLKDCFQSVKVNVVPCPDLTALPFGLLRPGLAGQSVACDVGSMAYLLPVADTSKRYSFDQVVDLSKvSG-GHLFGAGGGPFFTHGKSCEMAASLEFAngK---ICSNSTLH---gvyDEQTG------APQVIkaTDNNFGLVGQLLSTEGLPGSVIEVDVTGRLKEGSVYVFLREALTAAYGKldKPVVLGGVFVLTDSKARFHVlvsvnwvphvtisssmisylelftvdenlkapsliinqQP-NFPPYPVDTPARMAEFIKAFEMDPPVLGMGTLVSHDPyGIDLKLEHFHCYNeakn---LAGHFYWD-tEPEKAHYRLYLTVAKSLLRIDPKKKA------ ->tr|M3B464|M3B464_PSEFD Uncharacterized protein OS=Pseudocercospora fijiensis (strain CIRAD86) GN=MYCFIDRAFT_214637 PE=4 SV=1 ---KHPIAPPSLEELVDVLTPALRANFEKAKVSVERCPDLRHPPYYLAAPGLSGDECVADIGGQPNLFPEPRLECKYSLIEIAKEMQmDP-dgGHLLGAGAGPFHRIGLNSELAPNLSWSnnFEN--VVNQTYY---tkfDDSN-----grhAAVCERSPTTDCALMMNLYGSSGLPGDVIKISARARTGHhKSFTECIRKTLAEKYGDdRPISMGGIFLIKAGKAHFHVMP-DFPPKKqmpFKNAKQLn-DWLTYHDFEAPIVCLTVFHSADPgkKLGLRMEHTHCFSidga--NRGGHYHYDLpagdGVd-EVEYEAYFNTAKTIYRIDTPEVTLERDLH ->tr|A0A068Y3Y1|A0A068Y3Y1_ECHMU Ester hydrolase C11orf54 OS=Echinococcus multilocularis GN=EmuJ_000699900 PE=4 SV=1 ---NHNAYDVQEDELAEVLREGLKDCFRSVKVNVVPCPDLTASPFGLLRPGLAGKSVVCDVGSMTYLLPVADTSKRYSFCQVIESSGvCG-GQLLGAGGGPFFTHGKSCEMAASLQFAngK---IASNSTLH---gvyDEQTR------TPQVInaTDNNFGLVGQLLSTEGLPGSVVEVDVAGRLKEGSVYVFLREALTAAYEKldKPVALGGVFVLTDSKARFHVlQP-NFPPYPVDTPARRAEFIKIFEMDPPVLGMGTLVSHDPyGIDLKLEHFHCYNeakt---LAGHFYWD-tDPEKAHYRLYLTAAKSLLRIDPKKKA------ ->tr|F0XT09|F0XT09_GROCL Mgc81809 protein OS=Grosmannia clavigera (strain kw1407 / UAMH 11150) GN=CMQ_5752 PE=4 SV=1 ---RHALSPPLLHEVAAVLATALPRNYRCSSATVVECPDLRTAPFGLAAAGLSGRPTVADVGGQGNLFPTPRRDKNYGLVDVAARMQlDE-qrGALLGAGAGPNRVHGINSELAASLSWQggQEAk-NITDCSRS---iriAA-------dnhghdHVQCVLSGSTECALMANLYGSLGLPGPVLRVTARGRHGNaASFPEFLRATLHDAYGPdRQVSLGGVFLFKTGRARFHVMP-DFPPASalpFADRQAVe-RWLTFHDFAAPIVCLSVFHSADPhQLGLRIEHTHGFAadr--PAGGHYHYDHlardgHDdDEVEYEAYFNVADALVQIDPARANYEGRGE ->tr|A0A0D1ZUB3|A0A0D1ZUB3_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_01807 PE=4 SV=1 ---HRALSPPSLSSLAASISSGLSTNFAHWSCDVETPPDLTLPPYHLAAPGLSGSTRVADVGGPPYLESKLDLTRKYDLAAIAQDVNlPAs-gGFLLGAGAGPFFHLGHNSELMPNYAYGtaADPcsstssPAIRNRTHY---akiT-PSN----dPVCCPLPSSTGFGLMCNLYCSQGLPGPALHIKAKARTGPLNFTQSIQDGLKATFGEn-LISLGGVFILKSAKAKMHVMP-DFPKNPFQSRKELVEWLRFFDMefggsndpTGPLICLSVLHSGDDgGFDLRHEHTHCFTvdsggdldrETSKGGHYHFDLdeTKDQVEYEGWFNVAEDLYRVDQPGQ------- ->tr|A0A151JWH1|A0A151JWH1_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex septentrionalis GN=ALC56_06926 PE=4 SV=1 ---PIDLYVPDKTELAIVLQNELSTDFEEVKVEWVDCPDLTQEPFNLAAPGLCGDTALLDIGGIWNLFPFPIKDKIIYFQSILEKLDrTQs-dNLIIGGGLRTERPTNLLGELIMNVLISpaANEtmT-VKNKSRF---aliklIQNRKH---f--SLKFVtdPNPYCNIYGNFFISKGLREQVLKIHVKHRTGRDF-IVSLQHAIKRfSKCSq-LMGFGGTFIIKNGKTIQHIiRN-Y-WEVPIRKKKDIHNCIKYlKIQNSPIVAFATFVSSDRHKvmslkkfqDVYLNQWhv---Hansn---DSGGYYHETvPNnTNTEYLGYFSPATKLYRINPVSEFDEMRNF ->tr|A0A0N1H4U3|A0A0N1H4U3_9EURO Ester hydrolase-like protein OS=Phialophora attae GN=AB675_7754 PE=4 SV=1 ---KLELSSTTLADLASVISSGLRNSFSRSSCTVTITADLRLPPYHLAAPGLSGSPRVVDIGSPPSPPTQPHQKIRPP---LHRQTDrPPa-ipRAAHRRRRGPFHTVGKNCELAPNIAYSdG--gRKVVNRTHY---tklEPGSD----gslvPQCLQIEeESTGFALMANLYGSQGLPGEALHITATARTGShASFTDAIQDAIREHYGPdhPLISLGGVFVLKRGKANFHVMP-DFPGPKepeLDSDEAIAKWLRYFDFEAPVVALSVLHTCGEdvvkELGLRVEHSHCFSeaedgskdqGTGRGGHYHYDVdeTKDVVEYEGWFNVAEWVYRVDRPGPEV----- ->tr|T1L2K8|T1L2K8_TETUR Uncharacterized protein OS=Tetranychus urticae PE=4 SV=1 ---TYDLDQLPLDELSSTLQDHLSKFYGHVEVSVVDCPDLSKEPFNLAGSGLGGKTALADIGGVPYLMPVPYHpAPIYSFVNLGKRMGfQDa--HLMGAACVPFQITGSIAEFMPNISYSidE-TgkTLVNHGSYY---semVDDKK----YIMRP-LASDCTNTLANVFISENKPSKVIKIVASKRVDkRgESLTVAIRDILRIAYPEk-AISMGGMFLVRKGKIYIHVMP-NdFSKTPCDTEEKANEWLNFFEASAPIVGLVTLHSKDPGFNLRDEHTHCIGkg---EGGHYHHD-tTPDTIEYEAYLNIAQQIVRVDQPVVGNEMLKV ->tr|A0A0D1YEH9|A0A0D1YEH9_9EURO Uncharacterized protein OS=Exophiala sideris GN=PV11_06775 PE=4 SV=1 ---KLFLSPPPLAELATSISAGLSTNFSSSSCTIETPPDLTLAPFHLAGPGLTGSPRVVEVGDRSYLV-KRDLTRKYDLRAVARQIDmNPs-tGLMIGAGAGPFFVLGQNSELMPNFAYGtaAGSnaQSVRNRTHY---aklK-PDG----sVQCSALSPTSSFGLMGNLFCSDGEVGPCLHIRAKSRTGALNFTETIQEALKTSFGDKLISIGGVFLITSGRVNVHVMP-DFPAQPFKDRAAMTTWLRYFDMdtadGKPLVCLSVLHSGDDgGWGLRVEHTHCFTessdsQTDKGGHYHYDVddTKDTIEYHAWFNVAEYVYRIDYPAEHQRNTV- ->tr|A0A0L1JF69|A0A0L1JF69_ASPNO Uncharacterized protein OS=Aspergillus nomius NRRL 13137 GN=ANOM_001485 PE=4 SV=1 ---KLALNPPPLCELSQVIGERLSRNFGHVVANVVPCPDLRQPPFYLAGEGLCGSECIADVGGPPHLRPCPRLDKKYSLPTIMRMIEtRQ-rSFVLGAAAGPFHVVGQNSELMPNLARGhD--GEWLNETHY---akvN-EEG----qCHLAKVPdDSKDFGLMANLFASEGLPGDVIHIRAKGRTGGLNFTEAIQHALKTEYGAq-PISIGGVFLVRSGKTKLHVMT-DFSRDPCPGP--DHEWFKFYDSSAPLICLTVFHSVDSeSWDLRMEHTHCFSthg---MGGHYHYD-tTAEEVEYEAWLNTAKLLYRIDQPGQ------- ->tr|A0A0D2X135|A0A0D2X135_CAPO3 Ester hydrolase C11 OS=Capsaspora owczarzaki (strain ATCC 30864) GN=CAOG_001469 PE=4 SV=1 ---KKALHVPSLDELSAVLQHALQANFANASATpVEVCPDLTAAPYHLAAPGINGSPRLADVGGVPYLIPTANRNVLFDLQEVATKVDLPGAFFIGAGAGSWKYIGTNCELMPNVHLGaS------NNLTTTAIVA-HDKCEL--RPYD--TTQVGVLCNVLASEGVRGPVVHVKASVRTGPKDFLSCLHQAIVSRYGQQGVGLGGVFVIREGKAKIHVMP-DFSPVPLCSDAEVDQWLKFYEMQSPLVCLSTMVSGDLGLDLRLTHTHCFSNHGEGGHYHYDTTPEVVEYEGYLVPAEHIYRIGRPQPCMSPVHG ->tr|A0A167MH11|A0A167MH11_9PEZI Mgc81809 protein OS=Sporothrix insectorum RCEF 264 GN=SPI_08962 PE=4 SV=1 ---RLELSPPSLQEIAQVLAAALPRNYVASSATVVDCPDLRKPPFHLAAEGLCGGEVAADVGGHTHLVPRPRLDKNYSLPALAKLMQlSP-drGSLIGAGAGPNHVHGYNSELSPNLSWKdgFEHv--TRNLTHS---trvVGDR----AGVACGLSNSADCSLMVNLFGSEGRPGPVIKVTARGRCGNaASFTEFLQAALREAYGPdRQVSLGGIFLLKAGRAHFHVMP-HFPTptDDrppFEDQKTLd-TWLTFHDFAGPIVCLSVLHSADPqKLGIRLEHTHCFSgnk--PEGGHYHYDLgDEeSQVEYEGYFNVAHAFVRIDKPKPGAGDSQA ->tr|A0A0D2FGD0|A0A0D2FGD0_9EURO Rhinocladiella mackenziei CBS 650.93 unplaced genomic scaffold supercont1.8, whole genome shotgun sequence OS=Rhinocladiella ma ---KVQLDPPTLTALLPAIRAGFSSNFKNSIIEITQSPDLRQPPYYLATPGLSGHPRIADVGGQLFLAPGPDFSKKYDLLSVARQMEmSTe-cGQLIGAAAGPFYSLQINTELAPNIHWKldRDQatDVLYNETHY---tkiIASEP----gYRCSKIDhETTGFGLMGNLYGSDGLPGDLLHIVAKSRSGPLNFAATIQDALAKYFGDk-LISLGGVFVVTHGKIKVHVMP-DFPERKFERRADVGPWLRYFNLEAPLVCLSVLHSGNDrGLSLRMEHTHCFSinedgHAVSGGHYHYDLddTKDEVEYEGWFNIATVLYRIDQPPK------- ->tr|E2C2B0|E2C2B0_HARSA Ester hydrolase C11orf54-like protein OS=Harpegnathos saltator GN=EAI_16865 PE=4 SV=1 ---KKILYQPPVTELISVLTDGLTANFEKVIVKLGRCPRDPERQPNQ--YDLCGDPTILEIGGPAYLLPLAQKDKFYNIETLLRRIDyHG-sAFVIGAGAGLWPHTtdGSNCELIIHHHINtqI--GSVVNNSRY---afvDKCTGECVVa-QHLSHNeqHQATCPILANLYVCKGEPGMVIKVYAKKRTGKLDFIASMQKALGNYY-KdELVGLGGMFTMRNGKIKQHVMP-DYSNTPLTTEAQLNDWLHFYEMKTPLTAVGTFVSAETELDLRVQHFHSFAhn-NKMAGHYHIDTTPDTIEYEGYFNIASVLYRVDQPTNKLQFGKD ->tr|E4XHQ4|E4XHQ4_OIKDI Uncharacterized protein OS=Oikopleura dioica GN=GSOID_T00011035001 PE=4 SV=1 ---SKEIPPPPLEDIRVALEKALSENYKEAQVEIVDCPNLTEAPFGLAAPGLGGKTALADVGGVPYLVPGPAKwlERVYNLDHTAS----QvdIpgALVIGAGAGSKHDVGVNSELIPNIRTRggE--NKRRNLTHC---sriDPADDSKS-LLLRYEEdlNSADFTLLGNLFFSEGkSSSKVLKVTTKTRTG---TEGSIVTCMRKGLAEafsVPVGMGGTFLQAAGTVKYHVMP-EFSACPLDSDDKVNAWLRYFNFEAPFVNMATFISKDPDLDLRVEHTHGYStvnq---TGGHYHYD-vTPETIEYVGYFTPAQKIYRIDAPTETHMIGRD ->tr|A0A0G4NWG9|A0A0G4NWG9_PENCA Uncharacterized protein OS=Penicillium camemberti FM 013 GN=PCAMFM013_S002g000337 PE=4 SV=1 ---KHLRDPPPLEELAAVIEKALLSNFKTASATVAECPDLKQPPFHLAASGLSGSPRIADIGGQQHLFPRPILNAKYSLLSLAQDMEmSP-maGFLLGAGAAPFQDIGQNAELAPNLSWRssE--kapsfdepslLTFDNGTRV---ikvQ--GD----rdqTPVCDRTSSTNCALMVNLFGSDGDTGPVLKINAKARKGEe-NFTDCIRYGLQKVYGDsKPISLGGVFLLKSGKARFHIMP-DFPPEDqlpYRDRKQLeTEWLSYHIFQAPIVCLTVMHSSDPeGLGLRMEHTHCFGvngn--PKGGHYHYDIqdgd--EEVEYEAYFNVASVVYRVDRPGI------- ->tr|A0A131ZWZ3|A0A131ZWZ3_SARSC Ester hydrolase C11orf54-like protein OS=Sarcoptes scabiei GN=QR98_0016170 PE=4 SV=1 ---TIQLNEINLDELSNRLLDGLRNKFEHCSVSVVDCPDLTRPPFNLAASGLCGRTAIADVGGVPYLLPLVKRDKIYSFKQIANIVDpGQq-CFILGASAGPFHKIGHNSELMPNVLLEksADEgfKIRNDLTHL---aeiHDQNN-----R-FRLLksDHSEFGLLGDLFVSEGKPGKVLRIEVQNRKIidnndindeEkASFTTIIRKILQESYPNq-LISLGGVFLIEQGEAILHIMP-DFSDVPLNTEQEVNDWLRFFPMKSPLRCLTTMHSVVDgYRNLRSEHTHCFSdhn---QGGHYHNDIdp--KRIKYLAYLNTAKIIYRIDKPSITNISK-- ->tr|W9DVQ5|W9DVQ5_PELUQ Uncharacterized protein OS=Candidatus Pelagibacter ubique HIMB083 GN=Pelub83DRAFT_0385 PE=4 SV=1 ---KGTFTNHSLEDIASALKKGLSENFKNVEVEVVDCPNLRE--WDCPSEGISGNQKIIDVGGEPYMHDPNFIGAEFDYEEISKMIGsEKs--YALGAGSGAMSCLDGHCGeLVINENLItdE------SRSII---arvSPDK-------KCIVEkySARKHGGLGNIYYTDGKQGKVIKIKIRGRSGDqGSLPQVMRSSLSKNLKIkdnEHLSLAGVFRVLNGKIRSHVQP-DYKDIKheyYdpKQMKCVKDFLQFYEPvGPKLQCYTVLWTGDPtGGELNLresgEHThfHSYEhd--KDAGHYHFD-vTPEEIEYEGYFNTATEVHRVNNIYKELLSKNS ->tr|A0A0C9Q6Z5|A0A0C9Q6Z5_9HYME CK054 protein OS=Fopius arisanus GN=CK054 PE=4 SV=1 ---QRQLFAPSLQEIKNVLSPALAENFSEVSIEVVDCPDLTQQPFTLAAAGLGGSKTILEVGGPSFLLPSVQRDKVYELKSILNRINnGKmEkkGFVIGAGAGPWPRLSRNCEMMMNVIVSpT---DLKNETRL---swvGPNE-KCILe-ESLEN--DLRFALLANLYLSEGKPGKVLKVHAKKRTGNLDFIATMQKALESHY-KdKLVGLGGTFLLKQGKAKQHVMR-DFSSVPLTTEKALNDWLKFYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPETVEYLGYFSVAELLYRIDQPAVGVTFGKD ->tr|U4UGN1|U4UGN1_DENPD Uncharacterized protein OS=Dendroctonus ponderosae GN=D910_06428 PE=4 SV=1 ---TKSLYQPPLTEVAEVFRSYLPTNFQEVNVSVVECPDLTSKPFLLAAGGLNGNAKLLEIGGTQYLLPLVTREKLYDLLDIAKSVAl---epAFLIGAGAGPHPFIGGNCEGIVNLKIEkG---VADQQTRT---skvEGAdE-YMVVq-ILPNN--ETRIALLGNIFASEGKPGKVIKVHVKKRTGAKNFIETLRNAIEEKYGKdQLVGIGGAFLIAEGKAKQHVMR-DFSKTPLTSEDDVNNWLKFYEMSAPLTALGTFTSNDGaDLDLRVQHFHSFSTHGEAGHYHYDTTPDTVEYLGYFNVAQEVVRVDKPESGSKLGRD ->tr|A0A150UWN0|A0A150UWN0_9PEZI Uncharacterized protein OS=Acidomyces richmondensis BFW GN=M433DRAFT_7096 PE=4 SV=1 ---VHPLSPPPLDELARVLTSALEENYAYASATVVDCPDLSLSPFYLAGSGLCGCECVADIGGQPHLFPRPKLDKKYSLIECARDMKmNP-eyGMLIGAGAGPFHVIGGNSELASNLSWSggFNN--VQNLTRF---akiN--------gtaEIMVRKSPSTDCALMMNLFGSSGHSGHVLKIMAKSRRGSeKSFTECIRRALNNTYGSsTQISMGGVFLIRKGKALFHIMP-DFPNEDrlpFKDRHDLn-RWLTYHGFSAPIVCLTVFHSADPeSLGLRMEHTHCFStek--NEGGHYHHDLppdeADlEEIEYEAYLNTAKTLYRIDQPETFLGQHHR ->tr|G6CSG4|G6CSG4_DANPL Uncharacterized protein OS=Danaus plexippus GN=KGM_07584 PE=4 SV=1 ---EKSLHAPPLEEIVEVLSQKLPSNFEYVRVSAEESPDLTRSPYNLTSPGLCGDAKLVELGGPPYLVPTVRRDKLYSLTDLLRHLRr---dpALLAGAGAGPWPYLGVNCEGIINVYVKdS---AVSQGSHV---vsvSPVgapkgQSSFVQe-KLPAS--ETRTALLGNYLLSNGEPGMVIKVVAKKRIGEKNFITAIREALKEHY-GdKVVGLGGTFALLEGRAKHHVMP-DFSATPLCSDSDVDSWLHYFEHSAPLAHVGTLVTGDLGLDLRVQHFHGVSEHGQGGHYHYDTTPLAAHYEGYFTVAGSVIRVDAPENTHAIGRD ->tr|B3PAK2|B3PAK2_DROER Uncharacterized protein (Fragment) OS=Drosophila erecta GN=Dere\GG19819 PE=4 SV=2 ---EKPLYVPPLSELQNVIQVALAANFANVDVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLLPLVQRDKLYNIAEMTRKIQgP-GtVFAVGAGAGPWPIRGSNCEGIFNLSVNeKD--ELTNGSYT---atvRGEQEECVLe-KIPHT--EPRCALLLN------------------------------------------------------------------------------------------------------------------------------------------------------------ ->tr|A0A1B0ESX2|A0A1B0ESX2_LUTLO Uncharacterized protein OS=Lutzomyia longipalpis PE=4 SV=1 ---SKDLFIPDNKELKEALTIGLKKNFQEVSVDFVECPDLSGAPFNLANSGLCGNATIVEYGGAPYLLPLVQRDKLYDINEICLKICrERqMshYLAVGAGAGPYVLCNSNCEGIFNLAGGlDG--KIVSKSHL---alvDK-DKQCERr-NIPAS--ETRTALLGNIYLSEGKTGQVLKIHCKKRTGSNNFITQIRESLASHFVDKDIGLGGTFLLKSGKAHQHVMQ-DFSVTPIYTEEELNTWLKFYDMPAPLVAVGTLVTNEMDLDLRLQHFHSFSPSHWGGHYHYDTTPDTVEYEGYFGIGEKLYRIDKPKETHKFGRD ->tr|A0A084WLJ3|A0A084WLJ3_ANOSI AGAP006729-PA-like protein OS=Anopheles sinensis GN=ZHAS_00019143 PE=4 SV=1 ---EKALHTPSLGEIRDVLATGLKSSFATVNVEVVECPDLTKAPFHLAGRGLNGSPTLVEIGGPPYLLPNVDRSKLYDLVSVSQRALhD-tKkeFIAIGAGAGPFPLVNSNCEGMFNLRYTpPG--TVVSESHL---aviSPTDRTVTVh-KIPNT--ETRCALLGNILVAEGKPGQVLKVSCKRRTGKKDFIASIRTCLEGHYGERTVGLGGVFLLQTGKAKQHVMS-PFSETPINTEEELNEWLNFYDMPAPLINVGTLVTTECDLDLRLQHFHSFSTHGHGGHYHIDTTPDIVEYEGYFIVGERIVRVDKPVNTHKFGRD ->tr|A0A171AA04|A0A171AA04_TRIIF Ester hydrolase c11orf54-like protein OS=Triatoma infestans PE=4 SV=1 ---SVKLDCPKLEDVANALQKGLPQYFAETEVAVVDCPDLREEPFNLAAKGLGGKTVVIDIGGPGFLFPLHDETKIYDMKkDIANTVGm---ksCFIIGAGAGPWPYIGKNCEMMANILINdsTSS-I-VQKTYI---akv-NDkTEDIEVe-LLPNS--EMRFSLLANLFACEGTSSKVLKVFCKKRKQDENFITSISTTLEKAF-PnKTLGLGGTFLLKEGKARQHCMP-EFSKVPIRSNDDLNNWLKFYEMSAPLVAVGTLLSKDIpDLHVRVQHFHSFSNHGEGGHYHYDTTPETVEYLGYFNLGQTLCRIDQPEKKQYFDKN ->tr|A0A0K8TRB6|A0A0K8TRB6_TABBR Putative ester hydrolase c11orf54-like protein OS=Tabanus bromius PE=2 SV=1 ---EKPLHVPTFEEVQEVLLKELPTNFAEVSVEVVDCPNLSNPPFHLVKPGLNGSPTLIEVGGAPYLLPLVDRSKVYDIEKVARKAVgK-dVdLLAIGAGAGPYMLPGVNCEGIYNVNVKrDG--TLESGSYY---syvKGTEESCQAv-KIPHN--EARFALLANIFASEGNPGKVLRVYCKTRTGNQNYIESIRLALAKKYPEQCVGLGGAFLLKSGAAKQHVMR-DFSTTPIHTEEELNTWLKFYNMPAPLVAVGTLVTNEYDLDLRLQHFHSFSKSHWAGHYHIDTTPDYVEYEGYFTFGEKIVRVDKPVNTHKFGRD ->tr|A0A0P7B8H3|A0A0P7B8H3_9HYPO Uncharacterized protein OS=Neonectria ditissima GN=AK830_g8244 PE=4 SV=1 ---KLALSPPPLSDLATAIAAGLRTNFTTSTVSVSTPPDLRNAPFFLAGPGLSGNARVADIGGVQNLRPTPNLDAKYDLLGIARLMGmSDe-gGLLVGAGAGPFHHLGYNSELMPNIAYGsaSD-GVINNCTHY---akiT-QDG----gVRCEKIGESVGFALMANLFGCDGETGPILHVTARGRKARQSFTESIRAGIRAVYGDk-LVSLGGVFVIHKGKTKLHVMP-DFSDKPLRSPDDLDGWLRYFDTDPPLVCLSVFHSGDDgDLGLRMEHTHCFAgeggaVDCRGGHYHGDVdeTMQDVEYEAWFNVGEVLYRIGQPDGE------ ->tr|T1HIK3|T1HIK3_RHOPR Uncharacterized protein OS=Rhodnius prolixus PE=4 SV=1 ---TLKLDCPELEEVANALQKGLTQYFAEVEVAAVECPDLREKPFNLAAKGLGGKSAVIDIGGPAFLLPLPDESKIYDIKDIAKIVDlKS-CFVVGAGAGPWPYIGKNCEIMANVLIDscANStV---QKTHI---akvNNKTENCEV----EVLpsEETRCTLMANLYACEGTPSK-------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A060WWJ2|A0A060WWJ2_ONCMY Uncharacterized protein OS=Oncorhynchus mykiss GN=GSONMT00039591001 PE=4 SV=1 ---KFQLYVPILEELCDVLQRGLKNNFADAQVCVVDCPDLTQDPFKFPVKGLCGKPRITDVGGVPYLVPLVKVDKEYNMNTVSKEL----------elpgafilgaGAVSSKNVGMNAEMMPLVLTEaeGR--PAVNS------swfssiNPDNNQCLLe---KYSDkfSDCDFGLLANLYACEGKPGKVIEVRAKRRIGEESLVGALRKTMEEHYPDk-SLALGGTFLIQKGKAKIHIMPREFSACPLNSNDDVNKWLKHFEVSAPLICQSVMVSRDPGLDLRVEHTHCFSHHGEGGHYYIDTTPDTVEYLGYFMPAEFVYRIDRPSETHEVGRD ->tr|C3YJ39|C3YJ39_BRAFL Putative uncharacterized protein OS=Branchiostoma floridae GN=BRAFLDRAFT_126899 PE=4 SV=1 ---RKEAFVPPLDELASVLQAGLSSNYLDAKVKVVDCPDLTQPPFTLAAPGLCGSPRVADVGGVPYLIPSPQLDKKYNLEQVAGQV----------dlpgafvlgaGAGAAHVVGVNCEMMPNIRTTggAH--SRNNQ------trvsrvNTEDGTCILe---HYEDtyQCRDFCLLANLFFCEGKPGKVLEVKAKVRTGQENFVSCMRKTLEQQYGDr-PVALGGTFLLEKGQAKIHIMP-GFSKTPLQSEEDVNNWLNFFEMSGPLINLSVFVSRDPGLDLRVEHTHCFSHHGEGGHYHYDTTPEEVEYRGYFLPAEYIYRVDRPKVSHMIGRD ->tr|A0A177BUL9|A0A177BUL9_9PLEO Uncharacterized protein OS=Paraphaeosphaeria sporulosa GN=CC84DRAFT_1132340 PE=4 SV=1 ---KVPLSPPTLREIAVALQFPLAANYSHSTVDVVQCPDLRKAPFYLATAGLSGAEKISDVGGQPNLFPTPRLDCKWNLLDIARAMEmAP-hgGGLLGAGAGPFHIVGHNCELVPNIAWNdgFE--NATNSTYL---aqiRQ-------gEPSVEKSPSLDCALMINLYGSLGHSGPVIKITARGRVGDeKSITELMRKALANAYGDRMVSLGGVFAVKKGTSKYHIMP-DFPPEEelpFKNAKQLn-DWLTYHEFEAPVVCLSVLHSADPgkKLGLRMEHTHCASmdgr--DVGGHYHGDIng--EEVEYEGYFNVAKTLYRIEKPEVTLERDLH ->tr|D6X2L2|D6X2L2_TRICA Ester hydrolase C11orf54 homolog-like Protein OS=Tribolium castaneum GN=TcasGA2_TC010676 PE=4 SV=2 ---KKSLDRPPLEELAKVLNKGLQSNFEHVTVEVVDCPDLTQQPFTLAKKGLGGSPKLVEVGGVPYLLPLVKREKVYDLKKIATMIGs---dpAFIIGAGAGPHPYAGVNCEGILNMNIAkG---VVDQQTRI---skvNPSneE-VPIQe-ILPNN--ETRVALLANLFFSSGEPGKVLKIHAKKRTGPLDFIASIRQTLVNEY-KnKVVGLGGAFLLKEGKAKQHVMR-DFSKTPINTDEELNNWLKFYNMRAPLVAVGTLINNDHGLDLRVQHFHSFSHHGEAGHYHIDVTPETAEYLGYFNTGEEIYRVDRPVETHQFGRD ->tr|G1K3I6|G1K3I6_XENTR Uncharacterized protein (Fragment) OS=Xenopus tropicalis GN=c11orf54 PE=4 SV=1 ---NCSFHVPSLEEICSVLKSGLLKNFADVSVIVTECPDLSKEPFEFPVKGLCGKSRIADVGGVPYLVPKPRLDKVYNVNAVAKKI----------glpgayilgaGATSHKSLGMNAELIFSVQAEneSI--QAVNK------syvasvNPGDGSCLLe---KYRDrnNDNDFGLLSNLYACEGKPGKVIEVSVKRRIGQDNFVSCMRKSLKTHYGEk-AVGLGGTFLLKEGKAKLHVMPREYSACPLNTDEDVNGWLKFYEMKAPLICQSVFVSHDPGYDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFHPAELLYRIDKPSATHMVGRD ->tr|C4WVQ1|C4WVQ1_ACYPI ACYPI24700 protein OS=Acyrthosiphon pisum GN=ACYPI24700 PE=2 SV=1 ---RFKLNTPPLRCIIEAILPELLDNFENASVEVVQCPDLTQPPFNLTSEGLCGDENVFDIGDVTNLLPSLKREKLYNVKDLKQITGsDP-LFIIGACAGPYPFFGADSECVENVKMTgdRVEng----THVHM---tksD-DVPECFH----KSLpdDEMRFSMMANFFTSNGFKGEVLKIVCEVRKGPLSYSTCIKEAL-VkHFGNe-IIALGGVILIENGKVKVHViKP-SLTKIPIKSEKELGNLLHFIELSPPLVGVGCIVSHDPGLNLRLQHFhl---Ytdhn---QGGHYYNDTePEt--IKYTGYFGVSKQFTKID----------- ->tr|A0A0C2IGB5|A0A0C2IGB5_9PEZI Uncharacterized protein OS=Sporothrix brasiliensis 5110 GN=SPBR_07633 PE=4 SV=1 ---KYELSPPPLDELAAVLQTGLQQHFESVSVHVTRSPELREAPFHLAAAGISGRERIGDVGGPQNLRPLPRLDHKYHLREIMDLMEmQD-GLVIGAGAGPFHHVGGNTELMPNLSYTdG---VANNQTRF---ariVPATETDSVrdiatgtlaHRCRPLPapKSADSALLTNLYASDGAPGDVLKMVAHGRKPDsPDFTAAIQDVLRSTYSQ-PVSLGGVFVLRRGRALLHVMS-DFKTEP-RLPGNQDNWLTFFDVAAPLTCLSVVHARDPGLRLHLEHTHCFSerg---EGGHFHHD-sTPADAEYEAYFNTAKVIYRIDGPGE------- ->tr|R4WD98|R4WD98_RIPPE Uncharacterized protein OS=Riptortus pedestris PE=2 SV=1 ---SRDLHVPSLEDAQKALSKGLKNVFAEVSVDIVDCPDLSAEPFNLACKGLGGTTSVVEVGGPPYLLPKVDRQKVYDVKDIVKAIGl---qqCFVIGAGAGPWPFIGKNAEMVANVYIDgnNVK----SLTHI---aklKDDgTNNIEVs-VLPNT--ETRFALLANLFFSEGVQSKVLKVHCKKRTGSDNFVTAMRNALHDDF-PdKVVGVGGAFLLKSGKALQHVMP-DFSKSPLNSDEELNKWLEFYSMSAPLVAVGTLVSSDIpELDLRVQHFHSFSSHGEAGHYHQDTTPNEVEYLGYFNLGQKIYRIDKPPLTHSWGRD ->tr|K4FSW3|K4FSW3_CALMI Ester hydrolase C11orf54-like protein isoform 1 OS=Callorhinchus milii PE=2 SV=1 ---KFSLHVVGLEELCEVLQDGLKTNFAEVQVTVVDCPDLTKEPFTFAAPGICGNPRLADVGGVPYLIPVPQTQKVYNLNAVAQDV----------qlpgafiigaGAVSSKAVGMNGEFMPNIITEkdGK--PAVSH------sycatiNPANGKCVLe---KYTEtyKTMDFEMLANLYISEGQPGKVIEVKATRRTGESDFVKCMREALGYRYGDk-PVGMGGVFIIQKGKAKLHVMP-AFSSTPLESDREVTKWLKFFDMNSPLICQSTFVSHDPGLELRVEHTHCFSQHGEGGHYHYDTTPNIIQYLGYFLPAEHLYRIDRPNKSASAAFD ->tr|A0A0G4GDI3|A0A0G4GDI3_VITBC Uncharacterized protein OS=Vitrella brassicaformis (strain CCMP3155) GN=Vbra_17462 PE=4 SV=1 ---RHKLDPPPLDELANALSDGLARFFADVLVEVVDCPDLTAAPFGCAFSALGGDPCIIDVGGVDNLFPCARRGKYFDLSAIEQQIGaGRs--CFIGAGAGPFQEVQHNCEWICNVRLPeaNES-------RC---avmEGTDK----GSGYTIErpKTTCFGILGNLYACKGEPCKVLHIKAGRRTGkdpSgKDLPQCLASILASSFPSr-PVSLGGVMAMHAGKARLHIMS-DFTDDPIRSNDAIENWLNYFEVPAPMTFMFVSTSIDPGMDLRTVHTHGWHegk---YGGHYHND-tTPDEVSYEVYVNVAECIYRIDRVSQTPDFNRP ->tr|A0A0L8G520|A0A0L8G520_OCTBM Uncharacterized protein OS=Octopus bimaculoides GN=OCBIM_22000243mg PE=4 SV=1 ---KLPLKIPDEAELVSVLSKGLLKNFQDVSVNIVDCPDLREKPFQLAAEGICGNPCVADIGGPPFLLPTVHKEKIYNIKTISEISGQQDGFFIGAGAGPAHLIGVNSEMMCNVNLNkPD----GCQTYIAKVnPE-NGCFNLk--Q-IE--HSSFMLMANLLCCEGKQGKVIEVKASKRIGDDNFPTAIRKTLKSQYGSEPVALGGVFIIENGKAKLHIMP-DFSCKPINNVTELNNWLRFYEANAPLVCLGELISHDPDLDLREEHFHCFSPHGQGGHYHYDVTPEEVSYRAYFSVAKTLYRIDKPEHPLNFGKD ->tr|V4AUJ8|V4AUJ8_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_214298 PE=4 SV=1 ---KADLHVPTLEEAAKVLEKGLKNNFENVSVSVVDCPDLTQKPFNLSSPGICGNERLADVGGPPYLVPQYNKDKIYDVGKVSEEVGLPGAFVIGAGAGPWPLVGVNSEMICNVKLGkNG-QPTVNNTYIAKVgEK-DGKCQQm--QIKD--STEFCLMANLLCSEGKQGKVLQVKASKRTGPENFMSSLRKTLDSHYENKSVALGGVFLVETGKATLHIMP-DFSKVPLKSDGEVDEWLQYFEMDAPLVCLGELVSRDVNLDLRTEHFHCFSDHGQGGHYHYDTTPDTVSYRGYFTIPHSVYRLDQPKSNISM--- ->tr|E0VTT7|E0VTT7_PEDHC Putative uncharacterized protein OS=Pediculus humanus subsp. corporis GN=Phum_PHUM437900 PE=4 SV=1 ---TFDLSIVPLEDLAAGLNEHLKYNFEKVKVEVKDCPDLTQPPFTLACKGLTGNERIVEIGGVPYLLPKPRKDKLYDLKDLSKILNl---dpCYITGAGAGPWPYAGTNCEMIINMEHNgD---KVNNKTRI---akvNVTdG-KCIQe-VLPND--ECRNAVLSNLYCSSGEQGKVLEISCSKRIGNDDFITSIRKILGENF-KdKILGLGGVFVIKKGKVKQHVMP-DFSNREISSEDDLNKWLKFYEMNTPLIAVGTLVNNDPGLDLRVQHFHSFSHHGEGGHYHIDTTPNDVEYLAYFGLGEKLYRIDRPSQTHNYGRD ->tr|U6NKE0|U6NKE0_HAECO Uncharacterized protein OS=Haemonchus contortus GN=HCOI_00338900 PE=4 SV=1 ---IIETLKPSNEELLAIFEGALKENFKDVEIKLCQCPDLTAEPYNMTSTGFGRKMVIAEVGGPGNLFPVIHKEKDFDLKEICNGCEaPAs--FVFGPGAGPWQVVGRNCEMVADANFSssK---VA---TKI---aslPPG------htPTAYKMEviSSPKFSLMANLAVSAEpGPAQVVYCKASVRTGKDNFPETIRKGLAKHYGDk-CVSVAGVFMMLKGEAKLHVMP-DFPGCNFSSREELeKQWLRFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSshg---DAGHYHYD-tTPDTVVYEGYFTAAEKIYRFDEV--------- ->tr|A0A131YK09|A0A131YK09_RHIAP Uncharacterized protein OS=Rhipicephalus appendiculatus PE=4 SV=1 ---KHQLHCPSLEDVAKVLNDGLKSTFEHVEVSVVDCPDLKEKPFMLASEGICGKPCLADVGGVPYLVPIVQKDKIYNLEQVVKQTNISDPLVIGAGAGPFNVVGVNSEMMHNMK---YGDKPFNNSHYAKINE-DGSYELGRFTTS--CCEFGLMANLMISEGKPGKVIRVSAKKRTGADNFVTAMRKALAAHYGTNPVGLGGAFLLAKGKAKLHVMP-KFSTAPLLTNEAMNSWLKFFEMEAPLVCLSVFVSHDPGWDLRIEHTHCFSDHKQGGHYHYDTTPEEVEYLGYFNVAECMFRIDAPASTHQIGRD ->tr|W2RXT3|W2RXT3_9EURO Uncharacterized protein OS=Cyphellophora europaea CBS 101466 GN=HMPREF1541_03070 PE=4 SV=1 ---KRELSPPPLDELAGIIAAGLESNFEQSSVQVEPCTDLRKAPFYLAGEGLNGSTRVGDVGGPPHLAP-PDFSKKYDFMEISKLMEmPQe-kGFLLGAGAGPFYVLGCNAELIPNISY-EN-GEITNLTHY---akiA-KDD----qVECQKIETSTGFAFMANLFGSEGLPGPALHIKASSRKGAPNFTETIQAAVQEKYGDk-LVSLGGVFVIKRGRANLHVMG-DFPEKPLQ-RQDVDDWLRRFEFDAPLICLSVLHTGDDqGMALRPEHTHCFSvgg--KNGGHYHFDVedTKADVEYEAWYNVAEAVFRIDSPGRRY----- ->tr|A0A0X3PUS6|A0A0X3PUS6_SCHSO Ester hydrolase C11orf54 homolog OS=Schistocephalus solidus GN=CK054 PE=4 SV=1 ---VLRTFEASLEDIAAAFETGLKSCFQNVSVSVADCPDLTNKPFALPSSGLLGNNTVCDVGSFSYLIPVADTSRRYTFSEVISASKlQT-GQLIGAGAGPFFTAGKNCEMAAIVKVAenD---VRSNNTLH---gvyNKSED------KPGVLkaTDNNFALLGHFLATEGNPGKVLAVDVSVRAKDGSIYTFLREALTAKFGNesAPVALGGAFVLDNSKGRFHVMP-DFPKEPVDSPAKISSWLKFYEMSPPVMGVGTIVSHDPdKMDLKLEHFHCYSenga---EAGHFYYD-tQPETAHYRVYLAPAKSILRIDRAIK------- ->tr|A0A0P4WGG9|A0A0P4WGG9_9EUCA Uncharacterized protein OS=Scylla olivacea PE=4 SV=1 ---HKPLHVPPLEEVSSVLEAALKKNFAEAAVSVVECPNLTKTPYNLGAAGLCGSPRLADVGGVPYLMPTAQKDKLYDIKDLAGCVDLPNSFIVGAGAGPHKYIGVNSELMANVV---VGNEACNGSRAAKVDD-AGKCELLRLPQE--QTGCALMLNMFASEGKGGKVLKVQAKKRIGDKNLVSCLRQALENHYGDQPVGLGGTFRLLQGKAKIHVMP-DFSPVPLTCDNDVNKWLNFYDMEAPMVFLSTLISRDPGLDLRVEHSHGYGD-DRGGHYHYDTTPDTVEYEAYYNVAEFIYRVDKPVATHGFGRN ->tr|A0A087T5J9|A0A087T5J9_9ARAC Ester hydrolase (Fragment) OS=Stegodyphus mimosarum GN=X975_12710 PE=4 SV=1 ---KHNLHKPNLNEVAKVLQAGLSNTFSHISVDVVDCPDLKGKPYMLAAEGICGNPCLADVGGVPYLIPVARADKVYNLREIAKQIELPNALIIGAGAGPRHHVGTNCEMMPNIK---FNENEFNNTHIAKIGK-DGNCELVHLKD---SEEFCLLGNLFASEGKSGKVIKVTAQHRMTSENFVSVMRKTLAEHYKDQPVGIGGVFNIQVGKAKLHIMP-DYSKTPLKTDEDVNNWLKFYNQPAPLICLSTFISHDPGLDLRVEHTHCFSDHDVGGHYHEDTTPDIVKYEGYFNVADFIYRIDPPAETHQVGRD ->tr|A9UWD0|A9UWD0_MONBE Predicted protein OS=Monosiga brevicollis GN=20550 PE=4 SV=1 ---SRDFHVPSLDEVAGVFEAGLRANFATATASVVDCPDLTQAPFHLASEGICGSPRLADVGGVPNLVPLVNRDKVYNFVDVAKQIDLPGAFFLGAGAGSSRLAGVNCEMMPNTHIAtH----TI-KSYFAKVdPE-DGSMVL--NPYS--SNEFGLLGNFLASEGRPGKVIKVEAETRTGDKNFVTCMREALHAHFGDaMPVAIGGSFVIEAGNAKLHVMP-DFSKTPLQSDDEVAQWLKFYECQPPLTCLSVFVSHDPGMDLRVDHTHCFSQHGQGGHYHYDVTPKAVKYTGYFVVAEKVFRVDAPKETHTIGRD ->tr|A0A0B7ARP3|A0A0B7ARP3_9EUPU Uncharacterized protein OS=Arion vulgaris GN=ORF132368 PE=4 SV=1 ---KMALHQPSLSEVAEVLQKGLAQNFSFSEVSVVDCPDLTKPPFDLAAEGLGGQPRIVDIGGPDYLKPWPQKNRLYNFESIADLAELPGSFLIGAGAGPHLNVGVNCELVCNAKLGlNA----RNRTRIVKVdEK-VGTFKLe--E-ET--SGEFSLMGNFLISEGKPGKVLEIKAKNRTGTENFVSSIHKTLTAHYGDKAVGVGGTFLFQTGKANIHVMP-DFPTTPFENNEQIDSWLRYYEMDAPLINVGEIVSADPeNLNLRREHFHCFSNHGQGGHYHYDTTPDNASYLAYFNLGEVLYRIDLPEAK------ ->tr|A0A163MLZ4|A0A163MLZ4_DIDRA Nucleus OS=Didymella rabiei GN=ST47_g4 PE=4 SV=1 ---KIDLKPPPLEDLIDCIRSGLGQSFKSISVSVDQCPDLRQAPYHLAFTGLCERPRIADVGGQPNLAPTPDLTKKYDLLEIARLMEMPEgqGALLGAAAGPFHVVGMNSELMPNLSWKnK---EVSNETHFAKVRS-DGSAVC--EKLS--SHDCGLMANLFGSLGRPGPLLHITASSRTGPLNFTEAIRGALQDAFGTRTISLGGVFLISEGKAKLHVMP-DFSPTPLVTDKQKEEWLKFYEMKAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPADVKYEAWFNIAEVLYRIDRP--------- ->tr|Q5BYZ9|Q5BYZ9_SCHJA SJCHGC06040 protein (Fragment) OS=Schistosoma japonicum PE=2 SV=2 ---EFVLHKPSYHEVSAALESHLKDCFESVKCSITDCPDLSDTPFCLTLKGLCGKGTICDVGSFDYLLPVPKTDRHYDLLDVFKSAGiTV-GAVIGAGAGPFFLTGSNSEMVINISSEngK---VSKNSSLL---gsyDKENN------KPLITkaDNTKFALLGQMYMCEGKSGPVIELCVSGRIRDGKLDAMIREALHKKYGHlsSSVGLGGVIIQEKGKSLYHVLP-EFSQEPIDSNEKLRNWIKMFEMESPVISVGIVVSHDPhHLGLRLEHFHCFNqdht---NCGHCHFD-tHGPSVSYRAYFALAEHLVRIDQPK-------- ->tr|T2M672|T2M672_HYDVU Ester hydrolase C11orf54 OS=Hydra vulgaris GN=C11orf54 PE=2 SV=1 ---EKELFQPPLKEVCDVFLSGLLKNFKNASVTIEECPDLTKEPWTLASNGICGTPYLLDVGGVPYLTPNPQFHKIYNYETIAKVLPFDNVLILGSGAGPFHKIGYNCELMANMYISkV----FKNESRIASIDK-NGSYEL--QINQ--EKEFGILGNFLASEGVPGKVIKVNASVRKGGKNFIECIRESLRAKYPDNMIGMGGVFVIKSGKAKIHVMP-DFSCSPLNTKEDVDNWLRFFEMSSPLVCLSVFYNIDQGMDLRIDHTHCFSHHGDGGHYHFDTTPDDVSYEGFFVLAEKVLRIDRPC-------- ->tr|A0A026WXA5|A0A026WXA5_CERBI Ester hydrolase C11orf54-like protein (Fragment) OS=Cerapachys biroi GN=X777_14112 PE=4 SV=1 -----------------VLERGLSMNLKKVKIEWMDCPDLRL--YGFVAPGLCGTPALLEIGSLSYFCPTPRLDKKYYFRELLSLLNlTGq-dNFIVGAGTHIDPPT-----------------------------------------YDLaeFNSLCVIQGNFFLSERRPGKVLQVTAHCRTGPLNFVSAIQELFNLmrTETDp-LIGLGGMFMVSGSPTLHHImPA-YSRVTNLYTMKQVQQWLRYRKLIEPVTAVGTIMISLLLMdahdysrffqlpYLTKSHFhsHTLNqprs---CGGHFYTNCvnTNyLDAFYVGYFSFAEKLYCVDPPSRRDIHTNI ->tr|A0A0M9WC82|A0A0M9WC82_9EURO Uncharacterized protein OS=Penicillium nordicum GN=ACN38_g9838 PE=4 SV=1 ---KHLRDPPPLDELAAVIEKALLSNFKTASAIVAECPDLKQQPFNLAASGLSGSPRIADIGGQQHLFPRPNLNAKYSLLSLAQDMEmSP-kaGFLLGAGAAPFQDIGQNAELAPNLSWRsnS--napgfddpslLTFDNGTRV---ikvQRDGD----gdhTPLCDRTSSTNCALMANLFGSDGGTGPVLKINARARKGDe-NFTDCIRYGLQKVYGDsKPISLGGVFLLKSGKAKFHIMP-DFPPEDqlpFRDRRQLeTEWLSYHIFQAPVVCLTVMHSSDPdGLGLRMEHTHCFGangt--TKGGHYHYDIqdgd--EEVECDPSYLLKNILKDV------------ ->tr|A0A0N4U0N2|A0A0N4U0N2_DRAME Uncharacterized protein OS=Dracunculus medinensis PE=4 SV=1 ---------------mfcnWTWIKGILWNdsgGYRKMPSHKYQVSDFRQAPYLMTGSGIGSGLRIVEVGGIGNIYPVIKCDKFFDLKAICTKSDmPNa--FVFGPGAGPWHVIGSNCEMVADANFVnpS---NPVIASKI---iki---------nadNKAYELSttNSSYFSLMANLALSNAnEPADVVHIHVKKRLTDTNFPESVRRTVGAYYGKn-LVSIAGIFLVKAGKIKMHVMP-NFPSPNYcwKSADEVREWLKYFEMSAPVICACVIHSTNNeERKLRMEHTHCYSehg---DGGHYHCD-lSPEIVEYEGYFAPAESVYRIDLV--------- ->tr|A7SA42|A7SA42_NEMVE Predicted protein (Fragment) OS=Nematostella vectensis GN=v1g110650 PE=4 SV=1 ----------------TVLQDGLTKNFSHATVTVVECPDFRQPPWNFPAT--GKNLLIVDVGGPAYLLPLPQLNKIYDMNDVAAKADLPGGYVIGAGAGSHTSVGVNCEMIANVCTGtET-SNPVIQSKITKVnPE-DGSCVFq--D-YD--VCDFSLLANCLITEGKPGKVLKVEASKRTGDENFVTCMRLALGSYYGNRAVGIGGTFMIAKGKANFHIMP-EFSKTPLNSPEEVNNWLKFYDMSAPLVCLGVLESYDPGLDLRVEHFHGYNNHGEGGHYHYDTTPNEVEYVGYFTPAERLYRMDRPPKL------ ->tr|F2U224|F2U224_SALR5 Uncharacterized protein OS=Salpingoeca rosetta (strain ATCC 50818 / BSB-021) GN=PTSG_02390 PE=4 SV=1 ---SQVLETPPLEDVAKALETGLKGCFEQASVSVVDCPDLTAEPYHLAAPGISGSTRLVDVGGVPNLMPLVDRSKVYNFKQVAKDIGLPGAFFIGAGAGSSRLAGVNCEMMPNTNIAtQ----EI-RSYFAKVrPE-TGDMVL--EHYE--SNEFGLLGNFLASEGKQGAVLRVEASVRTGDDNFVTCMRQSLQAAFGDKPVGLGGVFVIEAGDAKLHVMV-RGVHCAA-------------------------NGDAVGWILRVEHTHCFSQHGQGGHYHYDTTPANVKYVGYFSVAEHIYRVDAPKVTHQIGRD ->tr|A0A194X4L4|A0A194X4L4_9HELO DUF1907-domain-containing protein (Fragment) OS=Phialocephala scopiformis GN=LY89DRAFT_620264 PE=4 SV=1 ---THPLPPTSLSNLISPLLTSLKQNFTDATISLVPCPNLTQPPFHLAAPGLSGHEAIVDIGGPAYLHPVPDFSKKYDLGRIVASLSsGEekGkgRLAIGAGAGPFHIVGQNSELIPNFYISaS--gNVTKNLTHY---akiDPSTQ----tCIAGPVPgASTAGALMANLFLSDGDPGPVLRITARNRIGDKSFTEAMRMGIEE----REISMGGVFVVEGAKVWAHVMP-DFCGER-LEDAEVGKWLRFFEWgGEGLVFLSCFHGVDFGVGVRVEHTH----------------------------------------------- ->tr|A0A017S4R7|A0A017S4R7_9EURO Uncharacterized protein OS=Aspergillus ruber CBS 135680 GN=EURHEDRAFT_518530 PE=4 SV=1 ---EITRHQLSLHELAEVLESALPKNYVTSSTTVVDCPNLPQSPFSLACEGLSGCQVIADIGVQPSLFPQPRLDEQYSLIVCVRLMGlDPe-qGAVVGAGAGPIHVHGTNSEIAPNLSWQgG--fGNVDNLTRA---arlVTTLA----gsrtRICCPYSDSTECLLMMSLYGSMGLPGPVLKVTARGQRGEsNSFTEFMRSALQDIYAQt----------------QFHVMP-SLPHSDelpFKSQAALDGSLSYYDISAPMVCLLVFHSADPnQLGVRMEHTQFQQg-------------------------------------------- ->tr|A0A1B6KUZ4|A0A1B6KUZ4_9HEMI Uncharacterized protein OS=Graphocephala atropunctata GN=g.45688 PE=4 SV=1 ---QKPLYCPSLDDVAQALKVGLSENFETVEVSVVDCPDLTQKPFSLASQGLNGSTTILEVGGVPFLMPLVDRSKVYDFKDMNQVTGv---npAFIVGAGAGPFRHAGVNCELVANLVVKdG---QVSSMSQI---aklKDEskGNEFVTe-TLQDS--VSTFALLANLFVSEGKPGKVLRVHCAKRKGKADFVTAARESLLKGF-PgKSIGVGGTFLVSGSKVKQHIMA-DFTSTPLDSEEKVDNWLRFYSMSPPLVGLGTFVTNDPGLNLRVIHFHSLSDHGEAGHYHYDTEPEKVEYLAYFNLGAKVVRVDRPQDESKLGHN ->tr|A0A1B6EDV6|A0A1B6EDV6_9HEMI Uncharacterized protein OS=Clastoptera arizonana GN=g.17798 PE=4 SV=1 ---EKSLAQPPLNLIAKAINDGLTKDFEYVQAEVVDCPDLTKAPFHLAAEGLGGSETIVEFGGVPYLMPLVQRDKVYDLKDLIQIIGi---dpVFVVGAGAGPHVYVQKNSELVTNISISkN---NIINLSRI---aklKDEqlNNDFEV-EILKE--ETRCSLLANLYTCQGKSSKVLKIHCKKRIGKNDFVSAVKQTLASTF-KdQCIGMGGTFLITGSKAKQHVMP-DFSKTPILNDDQVNEWLRFYEMGPPLVAVGTFVTKDPGLDLRLQHFHSFGtneSHPEAGHYHIDTNPDTVEYLAYLNTGSKVVRIDRPHETHQVGRD ->tr|A0A1C1XPK4|A0A1C1XPK4_9PEZI Uncharacterized protein OS=Diaporthe helianthi GN=DHEL01_13389 PE=4 SV=1 ---RVLLQPPSLNEVAAAVHNGLGSNFGTWSASVSTPPDLRQPPFHLAGRGLSGNPRVADIGGQSNLFPEVNLDKRYDLLKLSKQMEm--t-sGVLIGAGAGPFFDLGRNIELMPNIAFGsaSD-GDVSNCTRY---akvL-DDG----sALCEKIGTSTGCGLMCNVFGCDGETGSLLHVKAKGRTGKLNFTEAIQKGLADTYGDr-LISLGGVFVVCSGKLKMHVMP-DFPDEPLTSRQDVDQWLHWYDMDSPMVCLSVLHSGDDkGLGLRKEHTHCFGadagggeDSRRGGHYHFDLdeTTETVEYEGWFNVAEILYKID----------- ->tr|A0A1B6H7P9|A0A1B6H7P9_9HEMI Uncharacterized protein (Fragment) OS=Homalodisca liturata GN=g.15904 PE=4 SV=1 ---EKPLFVPPVEDVVQALQDGLASYFGSVSVESVECPDLTAEPFCLVTQGLCGSPRVVEVGGVSNFMPLYNPDKIYDLKDFNQLLAv---dpVVALGTGAGPFLDNHRCCELLANARISnG---EVQSLNRI---akvTNEnDRGYIVq-FLPKN--ETKFVLMANLFVSNGKPGKVLKIHCKNRIRDEDFPAAVRKCLAEKF-KgKELGLGGVFLVEGSKVCQHIPPEQFSKVPITSPEQLNNWLKFFNMNPPLVFVGTILTHDMGLEMILQHFHSFSSHGEGGHYHFDTDPHTVDYLAYFSLAEKAVHVDRPQCTStlKVDNI ->tr|A0A1I7RT80|A0A1I7RT80_BURXY Uncharacterized protein OS=Bursaphelenchus xylophilus PE=4 SV=1 ---KLDLLSPELEELAPILNVEMENYFQEIDVDIVDCPDLTKPPFNMTSRGFGPDLRIAEVGGVGNLFPKIRRDKLYNLKSICDLCElPNg--SVFGPGAGPRTSVGVNCEMVADANFGegT---VN---SKI---gkiDGQ--------SFVQEttCDPCFGLLANLGVSSGeT-DLVLKITARNRLTDYSFPHAIQQALFNHYRAk-IVSMAGIFIQKTGDAKVHIMP-DFPERDFSCWEE-eKSWLRYFKVRSPLICCSVLHSVNPGIDLRLEHTHCYSdhg---DVGHYYTD-iDPETAQFEGYFSPAKFLYRIDQIDSKGREK-- ->tr|A0A1B7YUZ9|A0A1B7YUZ9_COLHI Ester hydrolase c11orf54-like protein OS=Colletotrichum higginsianum (strain IMI 349063) GN=CH63R_00888 PE=4 SV=1 ---TFPLSPPSLEEIAAHLQAPLAANYTHASVGVVRCPDLRAAPFHLATEGLSGDEKIADVGGQPNLFPRPRLDTIWSLPEVARAIGmSP-erGGLIGAGAGPFHVLGQNSELAPNLGWSggLGEn-EIDNQSRV---iliERGSDGGDGttgkknAVSVRAAPSTDCGLMANLFASRGEPGPVLRIAARGRKGPeKSFTECIRQGLRAAYGGeRTVSLGGAFVVRAGRATYHVMP-DFPPERdlpFRDRRAVe-DWLTFHDFDAPVVGLSVLHSADPagGMALRMEHTHAFSaage--DAGGHYHFEAeg-EgDVIEYEGYFNTAKAIYRVDRPAGSS----- ->tr|A0A1I7RT20|A0A1I7RT20_BURXY Uncharacterized protein OS=Bursaphelenchus xylophilus PE=4 SV=1 ---VLDLAPPSLDELKAVIENGLHDYFVESSVTITDCPDFKTEPYNLEGSGLSPDLRIVDCGGHGNFFPKFQRHKQFDLKKISKTSElPQg--WIFGPGAAPRETVGVNAELVANANFNtnK---VN---CYN---grlTPD------GKGYLEGthSDTCFKMIANLALCSDeAGHRVLRISAKKRTGDGSFTEIIQKILASHYRNk-LVCLAGIWRFEKGRGYFHIVP-DYPEKDFEKLDDIwKNWLHFFELPAPMTMTTVIHSNDIGLDVPVEHTHGFSgrg---HCGHYHGD-vTPSEAVYDGYFLPATKLYRIDNTKHLS----- ->tr|A0A1S3J6D6|A0A1S3J6D6_LINUN ester hydrolase C11orf54 homolog isoform X1 OS=Lingula unguis GN=LOC106170181 PE=4 SV=1 ---KTRLYTPSLEEVAQVLQEGLSKNYSTVQASVTECPDLTKKPFMLAGEGLCGNPRLADIGGVPNLIPLAKREKIYNFEKIAGQLDLSNAFMIGAGCGPAHVMKVNTEMMPNLSVDgGGDGKVNNQTYLGRLnPD-EKSYDLf--V-SP--TTDFNLMANVFCSEGKPGKVIEVKVQKRVGEENFMSCMRKVLAAHYGTKPVALGGVFLVEKGKVKIHIMR-DFSKVPLNSDEEVNKWLTFHEASAPLVVIGELISHDPDLDLRVEHFHLFSDHGEGGHYHTDTTPDIIEYRAYLNVAEFMYRIDRPTETHNIGRD ->tr|W4Z4L2|W4Z4L2_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus PE=4 SV=1 --------------MVNILQTGLKICFETAEVNVVDCPDLTQQPFHLAAPGLCGSPRLTDVGGVPYLVPLAQKEKKYNLDTVAEQVDLPGAFILGAgagphaavgtnnekynldtvaeqvdlpgafilgaGAGPHAAVGTNNEMIANIRTRsAD-SEGDNQTRLSSIlPE-DGSYCLk--C-SP--TRDFNLLANLMASEGKPGKVLEVKCQTRRSPDNFVSLMRHFIHKHYGKdKFIGLGGVFVIEEGKAKIHIMP-DFSKKPLDTEEDVNKWLKFFEFKAPLICCSVFVTHDPGMDLRLEHTHCFSHHGQGGHYHHDVTPKTVSYRGYFVPAEWMYRIDPPTITHNIGRD ->tr|A0A1L9Q4X5|A0A1L9Q4X5_ASPVE Uncharacterized protein OS=Aspergillus versicolor CBS 583.65 GN=ASPVEDRAFT_57805 PE=4 SV=1 ---KYPLSPPSLEELADNLQAPLAANYEHSSVSIVQCPDLRQAPFHLASEGLSGNEKIADIGGQGHLFPRPLLDRIYTMDKIAEAMDmSP-skGSLIGAGAGPFHRVGRNCELSPNISWKqgYE--NVDNKTCF---aqiSPNT-----gDVSIKKSPSLECALMANLYGSESEPGPVIKITARKRRGQeRSFTECIRKALVAAFGDlKTISLGGAFLIKTGKARYHVMP-DFPPDNelpFKDSRQLn-DWLTYHDFDGPIVCMTVLHSSDPgkAMGLRMEHTHGYSpqgg--DCGGHYHYDVdg-DENIEYEGYFNTAKAIYRIDMPSVRLERDLH ->tr|A0A1L7WYC4|A0A1L7WYC4_9HELO Uncharacterized protein OS=Phialocephala subalpina GN=PAC_07660 PE=4 SV=1 ---KHALDPPPLVELASVISKGLQANYKSSTVSIIPCPDLTASPFHLAAPGLSGHESIADIGGPPFLHPLPDFSKKYSLPDILSHCGdGEk-ggRFAIGAGAGPFHVVGQNSELAPNISVDgD--GEVNNLTKY---akiGKNGE----VISGPVPeGSTDCCLMANLFISSGLPGNVLKITAKSELApnisvdgdgEvNNLTKYA------KIGKngEVIS-G---PVPEGSTDCCLMA-NlfissgLPGNVL-KITAKKTWS-----------------NGCdsstWLGLRMEHTHCFAngkgKDGKGGHYHGDTedTKDEVEYEGYFNIARIIYRIDRPGGGHE---- ->tr|A0A1S3CZ75|A0A1S3CZ75_DIACI ester hydrolase C11orf54 homolog OS=Diaphorina citri GN=LOC103507401 PE=4 SV=1 ---RRDLFVPPVDDVISVLNQGLGKYFKEVSVSFTECPNLTSHPFNLTSAGLSGSPSLVEYGGASFLEPIANKSKIYDLKDLVNVTQtKP-TFAVGAGAGSWRFAGTNCEERRQTMLFsaTTTakTETLTKLAL---kkepvyigvDDTKEEATVagle--QGYVVcpSEKRFLLLFTFLKKNHigeivawhvLLLQVIKIKVQTRIGKEDFVTSVRNVL-AaHYKDq-PVGLGGVILIENAPAKHHVMP-DFSTTPLETKDQLNEWLVFKDLTPPLISVGTVISADVVSfDIKAKS------------------------------------------------- ->tr|A0A1V9XJ15|A0A1V9XJ15_9ACAR Ester hydrolase C11orf54-like OS=Tropilaelaps mercedesae GN=BIW11_09664 PE=4 SV=1 ---IHEYHVPPLENVAKVLQEGLQKSFTEVSVTVEDCPDLKKAPFHLAAEGLSGLPRICDIGGVPYLIPLAQPEKRYNYEEVASLAGVPDGFFVGAGAGPCHIIGTNSELMPNIKCSgGSGSLTRNETHYARICE-DGKSHLmEKVPNG--TADFCLMGNVFLSQGKPGKALRLRLKRRTGSDNLTTAIRKILLETFGPdKPVGLGGVFLISKGKAKLHIMP-AFSKTALTSDEDVDKWLHYFEFRAPLICLSVMSSCDPGWDLRIDHTHCFSTHGAGGHYHCDTTPDEVEYECWFNVAEKLVRVDQPKETHQIGRD ->tr|A0A1W2WJF0|A0A1W2WJF0_CIOIN ester hydrolase C11orf54 homolog OS=Ciona intestinalis GN=LOC100177644 PE=4 SV=1 ---NVALHVPSMEELAEVVGVGLKKNYKEWSCSVVDCPDLSKAPFGLASNGICGRTRLVDVGGVPNLVPVSQyMEKVYNLQDISERVGTPGCFILGAGAGSKHVVGCNCELMPNFRCEgG-ERERVNLCHVARVKS-DGGYLLqnyENDHGS--SSEFSLLANLFCSDGKQGKVLEVRGKCRIGEKDLVGCMRGALKEHFGPnRPIGMGGTFLVNKGKIKIHVMP-DFSETPLTSDNDVNNWLKFYEVTSPFMCLSTFITEDCGLDLRVEHTHGYNaNSGVGGHYHYDVTPDEVEYIGYFTPAEFIYRVDRPSTTHNIGRD ->tr|A0A1W5A4D0|A0A1W5A4D0_9TELE ester hydrolase C11orf54 homolog isoform X1 OS=Scleropages formosus GN=cunh11orf54 PE=4 SV=1 ---KYELDVPPLQELCDVLHNGLKNNFADAQVRVVECPDLSQAPFHFPANGLCGSPRIMDVGGVPYLIPLVQLDKVYNMNTVAKEV----------elpgafilgaGAASSRTLGMNAELMPLVVTEieGR--SALNG------syfsyiNPADGTCLQe---KYSDrfDDCDFGLLANLYACEGKAGQVLEVKASRRTGEDSFVTCLRKTLEKFYSDk-CLGLGGTFIMQNGEAKIHIMPQEFSTCPLSSDEEVNKWLKHYTVRAPLICQSVLVSRDPGLDLRLEHTHCFSHHGEGGHYYIDTTPDVVVYLGYFLPAEFIYRIDRPSNTHRIGRD ->tr|A0A1D1VWM8|A0A1D1VWM8_RAMVA Uncharacterized protein OS=Ramazzottius varieornatus GN=RvY_15923 PE=4 SV=1 ---RYSLEVPSLEDLVDVFRIALEANFRNVAVRIVDCPDLTEPPYGMAAKGISKSTKISDVGGVRYLTPLPQLDHKYDLQTIAKESElSPPYFIMGAGCGPYQDVGCNCELMANVAVSsAGV------------vknesriaklDK-DGKCQI--ERLQ--TTNLAILGNFFLSAGEPGKVVEIRAEGRTGSENFVSILRQAVRARYQEKPVGIGGVFLVEKGSLNIHVMP-DFSKAPLETEGTVDQWLKYFTQPAPMVFMSVFVSEDPGWDLRCEHTHGYGvpdaegss-QNRGGHYHYDTTPDEVEYVGYFGCAETLYRIDRPPSSS----- ->tr|A0A1W0WDZ8|A0A1W0WDZ8_HYPDU Ester hydrolase C11orf54-like protein OS=Hypsibius dujardini GN=BV898_12290 PE=4 SV=1 ---KLELRTVGLDDIATVFQAALEANFTEVSVAVVDCPDLTLPPYRMAARGLSGSTKIADVGGVRYLTPTPQLDHIYSLRDVGKLTGsNDGCFVIGAGAGPFQETGCNCELMADAFISteADH------------skivsqtaklNK-DGKCVV--TSLT--TPSLAILGNFFVSKGEPGKVIEIRAKRRTGADDLIACLRKSLARQFGGTPVGVGGVFLVQKGRVNIHVMP-DFSKTPLATQDEVDKWLQYFEFPAPMIFQSVFVSEDPGLDLRLEHSHGHSlldekgecEHSHGGHYHYDTTPDEVEYVGFFNAAEALYRIDRPKGQ------ ->tr|A0A1V8UU19|A0A1V8UU19_9PEZI Uncharacterized protein OS=Rachicladosporium sp. CCFEE 5018 GN=B0A51_04439 PE=4 SV=1 ---KYTLTPPPLEDLATRLQSALAKNYGHSSVTVSQCPDLRLPPFYLATQGLSSNECIADVGGQANLFPKPRLECKYSLLEIAKAMEmGP-evGSLIGAGAGPFHVVGQNCELAPTLSWKgsFE--NIENRTYV---akiAKDS-----gEAIVSKYPSTDCALMVNLFGSSGLPGPVLKITARGRQGSeGSFPKCIRTALHEAYGDsKPVSLGGVFLVKSGKARYHIMP-DFPS--kpFGSRDDVe-DWLAYHTFAAPMVCLTVMHSADPg-LGLRMEHTHCFApnrr--NAGGHYHNDVesEDgEEIEYEAYFNTAKAIYRIDAPS-------- ->tr|A0A1V6T965|A0A1V6T965_9EURO Uncharacterized protein OS=Penicillium steckii GN=PENSTE_c010G10284 PE=4 SV=1 ---IYPRDPPSLLDLAEVIQRSLQFNFTEASVGVEQCPDLREEPFGLAAPGISGNPCIADIGGQPNLFPTPNFNAQYSLLELATDMQiSP-fgGSLIGAGAAPFQDIGHNAELAPNISWKpaGNHqkpdfsdhstLEIRNNTRI---ievNDE------kLPSCDGTSSTNCALMANIYGSNGQPGLVLKVKARGRIGDq-NFTNCIRHGLRDTYGDsRPISLGGVFLLKKGKAKFHVMP-DFPSKKdlpFRDREQLeKEWLTYHVFKAPIVCLTVFHSADPeLLDLRMEHTHCFDaegd--KKGGHYHYDIqedd--FEVEYEAYLHPASTIYRIDRPAS------- ->tr|A0A210QIS0|A0A210QIS0_MIZYE Ester hydrolase C11orf54-like OS=Mizuhopecten yessoensis GN=KP79_PYT16172 PE=4 SV=1 ---KASTHVPSLDEVAKALSGGLSQNFANVSTSVVDCPDLTKKPFMLVSEGLGGNPRLADVGGPGFLTPTPQTDKKFTFAQIAKLAELPGAFMIGAGAGPCQHVGCNSELMNNILLDsNG-GVVRNNAHIAKVnPE-NNACVLe--K-LS--CPEFNLMGNFLISEGKSGKVLEVKAGKRTGEENFVSCMRKTLKSYYGDKIVALGGVFLIEKGKANLHIMP-DFAKEPLHTNEEVKNWLKFYDMSAPLVCVGELVSHDPGMDLRVEHFHCFSEHGEGGHYHWDTTPEDVQYRGYFVLADYIYRVDQPPNITDLAR- ->tr|A0A1Y2LVB8|A0A1Y2LVB8_EPING Uncharacterized protein OS=Epicoccum nigrum GN=B5807_06372 PE=4 SV=1 ---KLDLHPIPLQELSDAIKTGLAHQFESTSVSVEQCPDLQQTPYNLAFAGLCGSPRIADVGGQPNLAPTPDFSKKYDLLDIARLMELPKeqGALLGAAAGPFHVVGTNSELMPILQWNgA---EVVNQTHFAKVKD-DGSALC--EKLA--SHDCALMANLFGCEGLPGDVLHITASSRTGSLNFTEAIRRSLEDAYGQKTISLGGVFLISKGKAKLHIMP-DFSFVPLITDEQKQKWLKFYETEAPLVCLSVLHSHDPGLDLRIEHTHCFSDHGEGGHYHYDTTPKDVQYEAWFNVAKILYRIDRP--------- ->tr|A0A1Y1K938|A0A1Y1K938_PHOPY Uncharacterized protein OS=Photinus pyralis PE=4 SV=1 ---CKPLHVPPLEEIADVLNKGLKKHFQDVKVEVVNCPDLTQMPFTLANKGLNGNTHMMDVGGPPYLVPFVQYDKVYDLCDIPDVVKm---ksAFIIGAGAGPHPYATVNCEAIMNINIEnS---LVKQQTRI---vkvNQTdG-TPVQe-QLPTT--ETRFALLGNFFICEGKPGQVLQVHVKKRVGCMDFIASIRGVLADHY-GnRILGLGGTFLLREGKAKQHVMP-HFSETAINSDDEINQWLKFYEMSAPLIANGTLITGDYDLDLRVQHFHSFSYHGEGGHYHIDTTPDTVEYLGYFNLAQDIYRVDKPEHTHKVGRD ->tr|A0A232ENF9|A0A232ENF9_9HYME Uncharacterized protein OS=Trichomalopsis sarcophagae GN=TSAR_003978 PE=4 SV=1 ---PQINHNAIFMFVIAVFLKALKENFEEAEVQVVDCPDLTEEPFTLAAPGLGGRLNIVEVGGPSFLLPSVQKDKVYDVQPLLKEIKyG--drAFVAGAGAGPWPYKNSNCEMMMNVMINsS---KLKNQTRI---ssvNTEdE-TCVLe-TLKGN--ETRFALLANLFLCEGITGKVLKVHAKKRIGKKDFIATMQQALAEHY-TdKLVGLGGSFVMKEGKAKQHIMP-DFSEKPLNSVKELDDWLHYYDMSAPLIAVGTFVSAETDLDLRVQHFHSFSHHGEGGHYHIDTTPDTVEYLGYFNLGEVLYRVDKPPVALQFGKD ->tr|E9IBH5|E9IBH5_SOLIN Uncharacterized protein (Fragment) OS=Solenopsis invicta GN=SINV_12208 PE=4 SV=1 ---SRALHQPPLDELMNVLAGGLTANFEEATVEMADCPNFSGRPYYFFKEGLCGNPIILEVGSPSYLLPTVQRDKYYDIKSLLQQLNyNH-dTLIIGAGAGAWPLRDSNCELIMKLNLKlnDN-FQVRNGTHY---afvDKNNQGCKLe-RLAENDNITTFALLANLYVCEGKPGKVIKVRAKKRTGKLDFIACMQKALEKHY-EnKLVGLGGMFEMKNGKVKQHIMP-DFSDTPLTTEADLNNWLRFYDMETPLIAVGTFVSAETDLDLRVQHFHSAFdkDPGLGGHYHIDTTPDTIEYEGYFNVATTLYRVDQPPNKVQFGKD ->tr|J9K119|J9K119_ACYPI Uncharacterized protein OS=Acyrthosiphon pisum GN=LOC100165490 PE=4 SV=1 ---RIDLNVPTLDRIIEALLPELSNNFETVSVDAVQCPNLTCSPFNLAAEGLNGDEMVIDIGSPSFLLPLVNLNKVYDIRDFAKVTGt---dpLFVIGAGAGPWPHVGVNCEFIGNVRLTsdDSV-NNNNSSHL---ykv-DPqTGSQVHh-RLPQD--ETRFALLANFYTSRGMTGEVLKIVCETRNGPLDFVTSIRKALAKYF-GdKPVGLGGVILIETSKVKVHVMP-DFSKIPLDSEADLNNWLKFFEVSTPLVALGYLVSHD-pGLDLRPQHFHLFGNHGEGGHYHHDTEPTTVKYTAYLNVAKKLIRVDQPETALLFGKD ->tr|A0A0A1WF70|A0A0A1WF70_ZEUCU Ester hydrolase C11orf54 OS=Zeugodacus cucurbitae GN=C11orf54 PE=4 SV=1 ---EKPLYVPPLHELKEIIQSALAQNFENVTVEVGDCPDLTDPFYGLVSSGLGGSPLLLEIGGPPFLLPLVQRSKVYNVKEIAQKALpG-kGkILAIGAGAGPFPLRNSNCEGIFNMAIDeEG--NLKNGSYT---akvHGAEELCVLe-RIPDS--DPRCALLLNLFISRGAPGPVVKVKCSKRTGEQNFVECIRKGLESHYKEQCVGMGGIFVLKKGAAHQHVMR-DFSKTPLNTEEELNDWLKFYNMPAQLNALGTLITHENDLDLRLQHFHSFSKSNWGGHYHHDTTPEVAEYEAYLNVAERVVRVDRPLETHKVGRD ->tr|A0A226EZ34|A0A226EZ34_FOLCA Uncharacterized protein OS=Folsomia candida GN=Fcan01_03965 PE=4 SV=1 ---EFVLPSVDIEDICKALNENLKAYFQNVDVNVVDCPNLAEPPYNLATNGIGGYCVIADIGGVPYLIPLVQRDKVYDLRTLIPECVgADkfPegWYISGAGAGPFKSQGSNCELIVNMYLSpdD--KVVNR-SKV---alTSSQNETD-LTVKTLSdTETDSSLLVNVLVSSGaGKVLDIKVSHKLDPA-TNFTTILRDCLNKKF--tasTPVGLGGLFTVDRAPTKIHVMR-DFSTKPLLTDNDVEEWLKFFRVEPPFMSQSILVSTDPGLDLRVEHSHGWTthsgpa---QAGHYHYD-tAPQDVQYHGIYAVASKIVRIDRPKETHNIGRD ->tr|A0A1Z5SX21|A0A1Z5SX21_HORWE Uncharacterized protein OS=Hortaea werneckii EXF-2000 GN=BTJ68_11441 PE=4 SV=1 ---THPLSPPTLEEICSTIRPALRANYKESTIDIVTCPDLTAPPFHLASQGLSGNESIADIGGQAHLFPRPLKEKQYSLIDCAKSMGmSQ-qrGLLMGAGAAPWHVIGQNAELAPNVSWEgsMDEeg-KVRNQTFV---trvESQG-----gHVRCERLPSMEFALMMNLYGCEGITGDVLRVTAKGRRGEqGSFTECLRQALHAEYGEeRQ------------------------------------------FSAPMVCLSVLHSADPeKLGLRMEHTHCFStdk--DEGGHYHHEIlpdgSDeEEIEYEAYFNTAKLLYRIDMPS-------- ->tr|C7ZLH7|C7ZLH7_NECH7 Uncharacterized protein OS=Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI) GN=NECHADRAFT_88680 PE=4 SV ---QLRLSPPFLEDIAQTLAKALPSNYITSSATV---TDLRQAPFKVTGEGLTGSETAADIGGQVDLLPQPYLHKTYSLIETAKLMGlSP-gkGAIIGAGAGPFLVDGTNSELAHHLSWGngFD--SVTNLTRA---aqlRKEG-----salPVCCPLSGSTDSGLMMNLYGSKGLPGPVIKPSARGRQGDvSSCADFIRQSLAKAYGVdLQVSLRSVFIIKSGKAKFHVIP-PFPKvdPPpfkFRNQEHLd-GWLSYHTFGGPMIRLAVLHCGDPeKIGIRLEHTHCYSner--GEGAHYHYDLqdsp-EnEEVEYERYFNTIKTFHQINYARTD------ ->tr|A0A0P4YAU6|A0A0P4YAU6_9CRUS Ester hydrolase (Fragment) OS=Daphnia magna PE=4 SV=1 --ENCQLHVPPLSELADVLRQGLESHFAHVQVEVVDCPDLSSSPFHLAAPGLGGEPCLVDLGGVPYLVPTVQRDRTYDLADLPGLMNVKDGtiLMIGAGAGPWQHLNTNCEMMTNLSLTLEEgkSNIVNGTRLATVD-PAGQRMLHVVPPE--QTRCSLLNNLLISRGQPStPVLRIRCQKRTGPNNFVTCMRNTVAQHYGDKPVGIGGVFMLDNGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPVLFYFMCFFfvlfHCSMtVRYIALLIKSSINPQIQVLGAY-----SCWTMARPGSIYS---- ->tr|A0A0G4FHT6|A0A0G4FHT6_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_17070 PE=4 SV=1 --EVQSLNVPSLTEVKEVLSRSLPAFFEEVEVEVTPCPDLRESPYLSSFQGLSspGDGNvILDVGGVdnllpr------PNKKKLYDLSDLVRQAveklGLTSHptCLVGAGAGPCHVYGMNSELICNTCITGSStsKVal-------MIPQEETGKEKHEVK--DDVSNKSSVLLNVMLTEGKPGEVLRIRLRGRAGkDergKDVPQCIADCLKAHYGEsRPVSLGGLLVLKKGRARLHCMP-DFSKEPIRTPEGVDEWLRWMEGEAPMRFMFVATSADPGMDLRLVHThgwge----agGRRYGGHYHNDTTPEAVEYEMVCMTAGAIARLDRVTQTPN---- ->tr|E9FYW1|E9FYW1_DAPPU Putative uncharacterized protein OS=Daphnia pulex GN=DAPPUDRAFT_43127 PE=4 SV=1 --ESCQLHVPPLDELAHVLRQGLALHFAFVQVDVVDCPDLSQSPFHLTAPGLGGDPSLVDLGGVPYLVPTVHRDRIYDLADLPAAMNVKDGtvSMIGAGAGPWQHLETNCEMMTNLSLSLEAgkSSslvVDNGTRLATVD-PSGRRILHVVPPK--QTRCSLLNNLLVSRGLPRtPVLRIRCQKRTGPDNFVTCMRNTVRQRYGHQPVGMGGVFMLENGQARLHIMP-DFSPCPLQTDADVNNWLHFYNATGPLINLSVFISHDPGLDLRVEHTHCFSt-HGEGGHYHEDVSPETVVYEGYFTPAERLFRIDRPSQTHG---- ->tr|A0A1D2MLD3|A0A1D2MLD3_ORCCI Ester hydrolase C11orf54 (Fragment) OS=Orchesella cincta GN=Ocin01_12942 PE=4 SV=1 --DEFQLEKLELETIQNALNKNLPKFFEKVSVSVSDCPDLTQQPYNLATEGIGGKGSvLIDIGGPpylipl------VNREKVYDLAKIIPEHvgkeDYPDGwYASGAGAGPWPSQGSNCEMVINLKLDKDGgvVSnk----SKVALTS-SGAEEDLTVKELGNEESRCALLANLLVSGGKG-KIIEIKCTKRIDkSSNFTAAIRQALKEEFGEeKPVGLGGLFTVTLSDTKIHVMR-DFSNTPLESDDDVNNWLKFFHIKPPMLFQSVLVSSDPGLDLRIEHAhgw-NLNgERSEAGHYHYDDMPDTVEYHGIYAVAQKIIRIDRPQETHQ---- ->tr|A0A1I8J432|A0A1I8J432_9PLAT Uncharacterized protein OS=Macrostomum lignano PE=4 SV=1 --RRFRLHRPDLVAVADCLDRACRDAFEDASVELiDSCPDLSEPPFCLASRGICggGGensGPvLSIAGGVpyllptp------QVEQRRYDLRNLLKATGHPDGLIIGAGAASSTRFGRNAELVANLGPLGNGcrVAsl-------RADGEDDGTENLANCRLsRPDFAEAGLMVDSLCSSGQTDgPVFRLRASRWRPeTatpdwsaaktrGRLAELLQRALAKEfSGCkLPVGLGGVFRLSGAAARMHVMP-DFSPTPLTCSAEVNSWLRFFNMPPPIVCCGVLISHDPHsWGLRLEHYhgwnp----sSEQCGGHYHYDASPDTAEYLGYFSLATSLLRMDPPGGVDS---- ->tr|A0A1X7V9X8|A0A1X7V9X8_AMPQE Uncharacterized protein OS=Amphimedon queenslandica PE=4 SV=1 --EKRQLHTPDLSHVAQVIESGLKENFKEASVNVVDCPDLTSSPWQLAAPGLGGAPRLLDVGGVpylmpli-------QREKVYDLAQVASLAGLPNGFILGAGAGSYRVAGVNCEMMANIKFSDPDsgAPhnigsysakv---------ST-EDGSAIIEKFP----YTEAGPLANLLLCEGTPGaPVLEIKARKRVGEENFVTCMRKSLAAYFGEGPVGLGGVFMIKKGKAKLHIMP-DFSQTPLTTNEGVNKWLQFYNMSSPLTCLSVFISCDPGLDLRVEHTHCFSSHGDGGHYHYDVTPQEVEYHGYYVIAEEIVRIDRPIKTHQ---- ->tr|A0A1U7UAF8|A0A1U7UAF8_TARSY ester hydrolase C11orf54 homolog isoform X2 OS=Tarsius syrichta GN=LOC103266437 PE=4 SV=1 --SEFSFHVPSLEELAGVLQKGLQDNFAEVQVSVVDCPDLTKEPFTFPVNGICGKTRIAEVGGVpyllpl------VNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHRPpvngsyf-------ARVNPEDGGCLLEKYSEKYHDFGCALLANLFASEGQAGKVIEVKAKRRTGQLNFVTCMRQTLEKHYGDKPVGMGGTFVIQKGKVKSHIMPAEFSSCPLNSDEEMNKWLHFYEMKAPLVCLPVFVSRDPTLPPVPTDYkrkaaRLFLpGRGQIN-LKEELSskPGTV-AQAY-----NLGT------------- ->tr|A0A1V8SQ10|A0A1V8SQ10_9PEZI Uncharacterized protein OS=Rachicladosporium antarcticum GN=B0A48_13383 PE=4 SV=1 --SKHTLKPPPLEDIATKLQSALANNYRHSSVTATECPDLRHAPFHLATQGLSGNECIADVGGQanlfpt------PRLECKYSLLDVAKAMEMDPEggSLVGAGAGPFHVVGQNCELAPNLSWKGSFdnVE--NRTYVAKIAKDSGEAMVSRC---S-STDCALMVNLFGSSGMPGPVLKITARGRKGkEGSLPECIRTALHAAYGDsQPVSLGGVFLVKSGKARYHIMP-DFPSAPFENRDDVEKWLTYHTFAAPTICLTVMHSADPGLGLRMEHTHCFAsdGQNAGGHYHNDVEsdLSD---------------------------- ->tr|T1L1G0|T1L1G0_TETUR Uncharacterized protein OS=Tetranychus urticae GN=107369328 PE=4 SV=1 --KTCDLEPISLKELSTTLQDHLSKIYGHVKVSVVNCPDLSKEPFNLAGSYLGgkTA--IADLGGIpylvpvg------YAAAPIYPLIHLAKKMGFQDAHLMGAACVPFQITGSIADFMPNISYSTDEqtGKttVNHGSYYSEMVDDKKHIMR-----HLASDCVTVLANVFISENKPSKEIKIVASKRVDkRgESLTIAIRDILRIAYPEKAISMGGMFLARKGKINIHVMPNDFSKTPCDTEEKVNEWLKYFEASAPIVGLVTLHSKDPGFNFRDEHThc----iGKGEGGHYHHDTTPDTIEYEAYLNIAQKIVRIDQPALNNE---- ->tr|R7V6P0|R7V6P0_CAPTE Uncharacterized protein OS=Capitella teleta GN=CAPTEDRAFT_151463 PE=4 SV=1 ----------------------------------------------------SGE---LPVQKAPLHCPPLdeVAKEIFDLSKVPEWTELPDAFMLGAGAGPRHVEGINCEMMTNLQVTPDGV--NNQSYIAKVGTEDNKYIVKKV---DNTTDCCLLMNLFVCEGKPSKVLEVKASKRTGPQNYMLCLRDVLAKHYGTQPVGLGGTFLMRKGSAKIHIMPD-YSDIPLESDAAVDAWLKFYEMKAPMIFMGYVISHDPDMDLRVEHFHGFSQHGDGGHYHYDTTPDEVEYVGYFNLGESMYRVDRPSVTHGIGRD ->tr|A0A095BUD1|A0A095BUD1_SCHHA Ester hydrolase C11orf54-like protein OS=Schistosoma haematobium GN=MS3_00610 PE=4 SV=1 ----------------------------------------------------SGKAIICDVGSFDYLLPVPkkdrvcivlsdLLAKHYDLLDVFRSAGVAAGAVIGAGAGPFFLTGSNSEMVINISSESG--VVKNGSLFGLYDKENNKPLLTK----ADNTKFALLGQMFMCEGKPGPVIELNVSGRIQDGKFDAMIREALHVKYGHlnNAVGLGGVIVQEKGKSLYHVLPE-FSQEPIDSGEKLRNWIKMFEMESPVISVGIAVSHDPHhLGLRLEHFHCFNQNqTNCGHCHFDTYGPTVSYRCYFSIANHLLRIDQPSKSL----- ->tr|A0A0B1S6J6|A0A0B1S6J6_OESDE Uncharacterized protein OS=Oesophagostomum dentatum GN=OESDEN_19781 PE=4 SV=1 ----------------------------------------------------GRNMVIAEVGGLGNLYPG-fHKEKHYD----------------------------------------LK-VA---SKITTLAENKSVP---FETKTINSTKFTLTGNFIVTAEPGPaEVVHIKCSERTGKLCFPDTLRESLEQRYGKECVVLGGLFRLLRGKARVHIAPE-FPEKPWKSMDEVEHWYQPFVVSAPLLCASVMHSYD-PgFKLRMQHTHCISDHNDAGHFENDATPEEAEYEGWFTAAEKMYRIDEI--------- ->tr|A0A0B1TGM0|A0A0B1TGM0_OESDE Uncharacterized protein OS=Oesophagostomum dentatum GN=OESDEN_04825 PE=4 SV=1 ----------------------------------------------------DRNLTIAEVGGPGNLFPT-iHKEKEFDLKKICEECHAPSAFVFGPGAGPWQVVGKNCEMVADANFAIPK-VA---TKVAFINDGQSTT---YKQSTIDSSKFSLMANLAVSGEPGPgEVVHCKCSVRVGKENFPEAIRKGLAEHYGEklfysRCVSLGGIFLLREGEAKLHVMPD-FPGCPFKSTEEIDKWLRFFTMKAPLVCASVFHSYD-PgHKLRMEHTHCYSEHGDAGHYHYDTTPETVVYEGWFAAAEKIYRIDEV--------- ->tr|A0A0N4VEE8|A0A0N4VEE8_ENTVE Uncharacterized protein OS=Enterobius vermicularis PE=4 SV=1 ----------------------------------------------------GSSLRIAEVGGVSNLFPT-pQKNKYYNLKELAETCELSDGFIFGPGGGPRHIIGTNCEMVADACFEKGKEKvA---VKMGVVTTKVPQG---HEMITTEKPEFCLMANLGVCKGSIPtSVLKIKARKRLGDLNFPEAVRRAIATHYKDQLVSCAGIFLLKGSKARIHVMPD-FPSGSFASAEEMEKWLKIFEIDGPIVAASVIHSKSVDnYKLRLEHTHCYNKH-EAGHYYCDTDPESVEYEGYFAVASAVYRIDLA--------- ->tr|T1GCC9|T1GCC9_MEGSC Uncharacterized protein OS=Megaselia scalaris PE=4 SV=1 ----------------------------------------------------------MEVGGPPYLLPLVdr--TKLYDIKTLSqRALGNKEIFAIGAGAGPFPLRGTNCEGIYNLKISADGKV-TNKSYSAKVHGPEENCVLEQIP-D-TETKFGLLLNLFLSEGKSGKVLKVHCKKRTGPLNFIESIRYALLDFYKEKCVGLGGMFMIKSGKAHQHVMRD-FSKTPIYSEEELNQWLKFYEMPAQLNGVGTLITHENDLDLRLQHFHSFSSSNWGGHYHYDTTPDTVEYEGYFNVGEKVIRVDKPVNTHKFGRD ->tr|A0A0C2CUP1|A0A0C2CUP1_9BILA Uncharacterized protein OS=Ancylostoma duodenale GN=ANCDUO_09117 PE=4 SV=1 ----------------------------------------------------GRKLVIAEVGGPGNLFPK-iRKEKEFDLQDVCKECHAPSSFVFGPGAGPWPVVGRNCEMVADANFASSK-VA---TKIASLVEGHTTP---YKMSIIDSPKFSLMANLAVSGEPGPaEVVHCKCSVRVGKDNFPETIRKGLAKHYGKMCVSLGGIFLMREGEAKLHVMPD-FPGCPFKAREEVDKWLRFFTMKAPLVCASVFHSYD-PgHNLRLEHTHCYSEHGDAGHYHYDTTPDTVVYEGWFTAAEKIYRIDEI--------- ->tr|W2T636|W2T636_NECAM Uncharacterized protein OS=Necator americanus GN=NECAME_11122 PE=4 SV=1 ----------------------------------------------------GRKLVIAEVGGPGNLFPT-lHKEKEFDLHQICKDCNAPSSFVFGPGAGPWQVVGKNCEMVADANFASSK-IA---TKVASIEEGQSKP---YKVDVINSPKFSLMANLAVSGEPGPaEVVHVKCSVRSGQDNFPETIRKGLAKHYGEKCVSLCGIFLLREGEAKLHVMPD-FPGCPFKAEEGVNKWLRFFTMKAPLVCASVFHSYD-PgHKFRMEHTHCYSDHGDGGHYHYDTTPDTVVYEGCMETSPSPSNPP----------- ->tr|A0A0B1TDA4|A0A0B1TDA4_OESDE Uncharacterized protein OS=Oesophagostomum dentatum GN=OESDEN_04823 PE=4 SV=1 ----------------------------------------------------GGRTEmesarSWQEGSPQNLVEGSslqeagifhcepfnFCLLSDTVQKICEECHAPSAFVFGPGAGPWQVVGKNCEMVADANFATPK-VA---TKVAFINDGQPSA---YKQSTIDSSKFSLMANLAVSGEPGPgEVGK--------------------------sRCVSLGGIFLLREGEAKLHVMPD-FPGCPFKSTEEIDKWLRFFTMKAPLVCASVFHSYD-PgHKLRMEHTHCYSEHGDAGHYHYDTTPETVVYEGWFAAAEKIYRIDEV--------- ->tr|G7YEP6|G7YEP6_CLOSI Ester hydrolase C11orf54 homolog OS=Clonorchis sinensis GN=CLF_106094 PE=4 SV=1 -------------------------------------------------------MTECED----------lvnailatlesRSLLRYDLLDAFSLSHIGSGLIMGAAAGPHFVAGINSELVANLSAIDGK-VLQNGSYCGSYDAKNNLPVSTL----SETSLFAMVGQMFLCEGKRGKVIQLTVSGRTREGKFDALLREALASKYAAldRPVGVGGVVVQETGKCLFHVLPE-FCAEPLDTPEKLKQWLKFFEMEAPVVAVGTALSHDPQkWKIRLEHFHCFNNDrTKSGHCHFDCDGPTASYTAYLVPGKRLLRVDPPN-------- ->tr|A0A182ZLD2|A0A182ZLD2_BIOGL Uncharacterized protein OS=Biomphalaria glabrata PE=4 SV=1 -----------------------------------------------------------------------------------------------AGAGPNHKVGINCELICNVKVGEG--A-INKTRIAKIDETTGSYVLEEET-S-------AIVHALKFHLKKNQVLQIKAKNRIGIENFVSCIHKTLTAHYGDKAVGLGGTFLLQTGKANIHVMPD-FLDEPLITDEQTNAWLKFFEMDAPLIHVGEIVSADPQkLHLRQEHFHCFSHHGQGGHYHYDTTPDDAAYLAYFSVAEFVYRIDLPETRNFIF-- ->tr|A0A1L1SSF8|A0A1L1SSF8_MOUSE Protein 4931406C07Rik OS=Mus musculus GN=4931406C07Rik PE=4 SV=1 ----------------------------------------------------CGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKVIKLPGAFILGAGAGPFQTLGFNSEFMPIVQ--TASEHnqPVNGSYFAHKNPADGACLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGELNFVSCMRQTLEEHYGDKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD ->tr|A0A0D2YJX9|A0A0D2YJX9_FUSO4 Uncharacterized protein OS=Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) PE=4 SV=1 ------------------------------------------------------------------------MDCVWSMTELAeaMDMDPAKGGLLGAGAGPHPVIGQNCELAPNIGWQGSFENVKNESRYAKIDKETSAVHVDK----SPSLDCALMINLFGSSGNPGPVIKITARKRTGSeRSFAECIRKGLRLAYGDeQTVSLGGLFLVKKGKAKYHIMPD-FPTekdLPFNNRKDVDSWLTFHDFDAPMLCLSVLHSADREgrMGLRIEHTHCYAADgkNAGGHYHYDLddTEDDIEYEAYFNTAKMIYRLDRPN-------- ->tr|A0A1L8H894|A0A1L8H894_XENLA Uncharacterized protein (Fragment) OS=Xenopus laevis GN=XELAEV_18015384mg PE=4 SV=1 ----------------------------------------------------VIETECPDLSKEPF------EFPVYNVNSVARKIGLPGAYILGAGATSHKSLGMNADKKTRLAEQAESAGtvAVNKSYVASVNPGVGSCLLEKYRDRNNDNNFGLLYNLYACEGKTGK------------------------------------------------------SACQLNSDEDVNGWLKFYEMTAPLICQLVFVSHDPGYDLCLEHTHCYSHHVEGGHYHYDTTPNTLEYLGYFHPAEFLYRIDKPSDTHMVGRD ->tr|L8YBB9|L8YBB9_TUPCH Uncharacterized protein OS=Tupaia chinensis GN=TREES_T100004622 PE=4 SV=1 ----------------AVLQKGLKTNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLINRE---------------------------------------------------------------------------------------------KVIEVKAKRRTGQLNFVTCMRQTLGNHYGDKPVGMGGTFIVQKGKVKTHIM---------------------------------------GFDLRLEHTHFFSHHGEGGHYHYDTTPETVEYLGYFLPAELLYRIDQPKETHLIGRD ->tr|A0A0B2VAD5|A0A0B2VAD5_TOXCA Ester hydrolase C11orf54 OS=Toxocara canis GN=Tcan_18580 PE=4 SV=1 ---KLSLKVPPLEELSSILDPALRKNFGQISIDIVDCPNLREAPFSMTGAGIGNGLRIAEVGGIPNLYPRG-GKKIFNLKKVCETCEMPHAFVFGPGAGPFEAVGHSSELVANANFIE-HEYKVA-NKVSWVVPSGKG-----YTMSTiDSSDFEITANLAISDGCPGrKVLRIRAAKRNGEMNYPEAIQKALGAHYGDTLVSLAGLFVLQKGKVRMHVLP-DYPESPRKADEKKDDWlqyMRYFEMDAPIVFASVVHSNDvGGYKLRVEHTHGYSEHGDSGHYHIDTTPNTVEYEGYFSPANIVYRIDMV--------- ->tr|A0A0M3I6F9|A0A0M3I6F9_ASCLU Uncharacterized protein OS=Ascaris lumbricoides PE=4 SV=1 ---KIVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADADFTTDHQNNVA-TKVSRVVPNGKG-----YEMSTiDNADFVLMANLAISDGFPAgKVLRVHAAKRNGEMNYPGAIRKALIGYYGNSLISLAGVFLVKKGKVRMHVMP-DFPGCPWETIEEMdKEWLKYFEMKAPLVCASVLHSNDiGGYKLRLEHTHCYSEHGDAGHYHYDTTPDEVEYEGYFAPAKFIYRVDML--------- ->tr|A0A0M3KCR7|A0A0M3KCR7_ANISI Uncharacterized protein OS=Anisakis simplex PE=4 SV=1 ---KINLVVPSLDELKSVLHDSMVKNYESVSIDIVECPNLRESPFRMTGSGIGNNLRIAEVGGIPNLYPHG-TKKIFNLKKVCETCELPEAFVFGPGAGPFDAIGHSSELVADANLIK-SQFKIA-NKVSWIVSSANG-----YTMSTtDSTDFEITANLAISDGCANrKI---CATKRIGELGYAESIQRAIESYYGRnhQLVSLAGLFLLHKGDVYMHILP-DYPVSPRKQDEKFfR------ESERKTTGXSVVHSHDnDGYKLRVEHTHGYNESNKsGGHYHIDTTPEIAQYEGYFAPAHCIYRIDKI--------- ->tr|E3N569|E3N569_CAERE Putative uncharacterized protein OS=Caenorhabditis remanei GN=CRE_19401 PE=4 SV=1 ---VIENHVPSLEELKEvrlvircsklqptqVFQKSLDANFETVQVDVVDCPNLSEPPFHQTSSGFGQNLKIAEVGGPGNLFPGFHTDHQFDIRTIGKVCEHPEASVFGPGAGPWPVVKKNCEMVADVNLKTG---KTA-TKIAeiy-----QEK-----YRQRTiEEPKFSLMANLALSDADKSaKVVHFKASVRTGEKNVTHCIRDGLQEHFGERPVSLAGQFIIHTGQAKLHVMP-HFPGCPFANNEEVDKWLNYFTMDAPLVCATVMHSYDPGHNLRLEHTHCYSEHGDAGHYHYDVTPATVAYEGWFAPAGKVYRIDEV--------- ->tr|H3G356|H3G356_PRIPA Uncharacterized protein OS=Pristionchus pacificus GN=WBGene00118571 PE=4 SV=1 ---RLETHVPSLEAIADAFRSKLPSNFETVTVDIVECPDLSSAPFNLTSPGFGKNLVIAEVGGPGNLFPTIHKEKAFDITKICSTCEQPRAFAFGPGAGPWPIVGVNCEMVADVNCADN---KVG-TRTAkieg------DS-----YKVEQiDSSTFSLMANLAVSEPQGGqRVVHIKAKRRTGKTNFPDSLRQSIVKAFDGKLVSLGGFFVLHSGRAKLHVMP-DFPGCFETEeevrltnephevnaFQIVSQWLRYFEMNAPLVCATVMHSNEgNGHKLRVEHTHCYSAHGDGGHYHYDTTPDEVEYEGWFAPASAVYRIDEI--------- ->tr|A0A183V321|A0A183V321_TOXCA Uncharacterized protein OS=Toxocara canis PE=4 SV=1 ---KIILNAPSLEELRPILENALKKNFEQVSVDIVECPNFKAPPFSMSGAGIGNDLRIGEIGGIGNLYPSPRTDKVFDLKEICVTCEIPEAFIFGPGAGPFHVVGHNCEMVADANFIE-RQNNVA-TKIAEITASGKG-----YRMSTiDKTGFALMANLAISDGRPNgKVLRIRATKRNGEMNYPESIRKALTAHYGETLVSLAGVFVLKKGKVHMHVMP-DFPGCPWKTHEQVNEWLKYFEMNAPLVCTSVLHSNDvGGHKLRLEHTHCFSEHGDAGHYHYDTTPNDVDYDGYFAPANVIYRIDMV--------- ->tr|A8XV43|A8XV43_CAEBR Protein CBG19223 OS=Caenorhabditis briggsae GN=CBG19223 PE=4 SV=1 ---VIENYVPSLEELKEVFQSSLKLNFETVEVDIVNCPDLSKSPFHQTSSGFGQNLRIAEVGGPGNLYPGFHINHQFDIKTIGKVCEHPEASVFGPGAGPWPVVRQNCEMVADVNLKTG---RVG-TRIAeidt---KNEKL-----YVQRTiDVPKFSLMANLALSDADKSsKVVHFKASGRTGQKNVTNCIRDGLQEHFGEKVVSLAGQFIIHSGQAKLHVMP-HFPGCPFENNEEVDKWLNYFTMSAPLVCSTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPDSVSYEGWFAPANRIYRIDEV--------- ->tr|Q3Y402|Q3Y402_CAEEL Uncharacterized protein OS=Caenorhabditis elegans GN=C24B5.4 PE=1 SV=2 ---VIDNHVPSLEELKMVFQTSLLSNFENVEVNIVDCPDLSKPPFNQKSSGFGHNLRIAEVGGPGNLYPGFHIDHQFDIPKIGKVCEHPEAAVFGPGAGPWPIVGQNCEMVADVNLKTG---EVG-TRIAeins---NSDKR-----YVQRIiDEPKFSLMANLALSDADKSsTVVHFKASVRKGEKNLTNCIRDGLQEHFGKKIVSLAGQFIIQTGKARLHVMP-DFPGCPFENNAEVDKWLNYFEMSAPLICATVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEI--------- ->tr|A0A183FJK9|A0A183FJK9_HELBK Uncharacterized protein OS=Heligmosomoides bakeri PE=4 SV=1 ---VINTLKPSNNELRSVIETALWKNFKNVQVAVSNSPDLSKPPFRMTSNGFGKKLTIAEVGGMGNLFPVLRKE-EYDIREICSLCDKKSAFVFGPGACPKSVMGTTGELVADVNLSTN---KAR-CQSPsishgmaaravaskvttIVNDECLP-----YKTTAiDSTKFSLMANLAISEEPGPaEVVRATFLVA----------PPTVSRAHTCSCVSLAGIFLLLRGQASAHIVP-DFPTGNFKSIEEEEQWLRKFTLKAPLVCTSVFHSYDAGHRLRMVHTHCYSDHNDAGHFYTDITPESAVYEGWFTAAEQVYRIDKV--------- ->tr|A0A0D8Y0E7|A0A0D8Y0E7_DICVI Uncharacterized protein OS=Dictyocaulus viviparus GN=DICVIV_03527 PE=4 SV=1 ---IIETLKPSNRELRPIVETALKTNFKNVSVEVVSCPDLSIEPFSMTSTGFGRKLVIAEVGGIGNLFPIIHKEKEFDLQEICDSCQAASSFVFGPGAGPWKLVGKNCEMIADANFSIS---KVA-TKIVsisssdpPSY-----------TLSIlNSPKFSLMANLALSEPG---TGECTANVRFELEMIIflklyEEGLLNITEKSVVLCVSLAGIFLLREGEAKVHVMP-GFPGCSFNTKEEINKWLRFFTMKAPLVCASVVHSYDAGYKLRMEHTHCYSSHGDGGHYHYDTTPDTVVYEGWFTAAEKIFRIDEV--------- ->tr|U6NTY2|U6NTY2_HAECO Uncharacterized protein OS=Haemonchus contortus GN=HCOI_00414200 PE=4 SV=1 ---IINTLKPSNNELRSVIENALWKNYKNVQVTVDTSPDLSKPPFRMTANGFGKKLSIAEVGGMGNLLPILRKD-KLY------NTEKKSAFVFGPCASPASIVGATGEFIIDANFATS---KV------agkvtiQQKGHTSP-----YKMLIfDTPKFDLMANLAISEEQGPgEVVHVKCSERKGEDNL-pGCIRKELARHYGPSCVSLAGIFLLLQGKADVHIVP-DYPTDNFKSMDEVRKWFHMFNVKAPLVCATVFHSYDPGHNLRMEHTHCYSDHNDGGHYHTDTTPDTVAYEGWFTAAEKIYRVDQV--------- ->tr|A0A158PFA5|A0A158PFA5_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis PE=4 SV=1 ---LIETLKPSNSELLPIVESALKSNFKNVTVEVGPCPDLSAEPFSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDL-KICKVCQSPFSFVFGPGAGPWKVVGRNCEMVADANLTTA---KVI-LSS-gyvdpLNRRYMLI-----FHYIIlNASRSL-----LFSLCR---LVHCKCSVRIGKDN--fpe-TIRKALAKHYGERCVSLAGIFLLREGEAKLHIMP-DFPGCQFSSSEEVDKWLQFFTMKAPLVCASVFHSYDPGHKLRMEHTHCYSSHGDAGHYYYDTTPDTVAYEGWFTAAEKIYRIDEI--------- ->tr|G0NTX6|G0NTX6_CAEBE Putative uncharacterized protein OS=Caenorhabditis brenneri GN=CAEBREN_29657 PE=4 SV=1 ---VIENYVPSLNELKEVFKSALTSNFETVEVDIVDCPDLSKSPFNQTSSGFGCNLRIAEVGGPGNLYPGFHIDHQFDISTIGKVCEHPEASVFGPGAGPWPVVGQNCEMVADVNLKTG---KVG-TRIAecdv---KTKDL-----RS-KSiDVQNS-YISKYQPG---------------KERKTLQTVLeKDYRNTSERSEVVSLAGQFIIHTGQAKLHVMP-HFPGCPFKNNEEVDKWLNYFIMNAPLVCTTVMHSYDPGHNLRLEHTHCYSDHGDAGHYHYDVTPETVSYEGWFAPASKIYRIDEV--------- ->tr|A0A1R3R7E5|A0A1R3R7E5_9EURO Uncharacterized protein OS=Aspergillus carbonarius ITEM 5010 GN=ASPCADRAFT_179137 PE=4 SV=1 ---CFILQPPPLEELRDVIQNGLRNAFETAFVEVTTCPDLSQSPFHLSAPGLCGDEKIADVGGPAYLQPVSDLTKKYTIPKILDLVGMeGQGFAIGAAGGPFHVVGKNSELVPNLARDANGKWQNL-SRYVhIDDDEKMN-----LSMVPkDTKDCGLMANLFISRGHQGESLHIRAKGRRGQLNFPETIQELLRVNYGGRPVSLGGVFLVKQGKAKLHVMT-DFSTSSCPG---PdHEWFRYYEADAPIVCLTAFHSVDyLDWNLRMEHTHCFSESGVGGHYHYDTTPDDVEYEAWLNTAKAVYRIDQP--------- ->tr|A0A146MXI0|A0A146MXI0_FUNHE Ester hydrolase OS=Fundulus heteroclitus PE=4 SV=1 -----QLHAPALEELRGVLQAGLETNFAEVQVSVVECPDLTTEPFLFPVKGLCGNPRITDVGGVPYLIPLPQKHKEYNMNIISKELELPGAFILGAAAAPSRIIGMNAELMPLVLTEAEGRPAVNGSYFSSINPADGQCLQEKYSDKFSDCNFGLLGNLYACEGKPGKVIEVRAKKRTGSNSLVTALRKTLEAQYPEKSLALGGTFVIQKGKAKIHIMPREFSACPLNTNDDVNNWLKHFEVSAPLVCQSVLVSRDPV-------------------------------------------------------- ->tr|E2A095|E2A095_CAMFO Ester hydrolase C11orf54-like protein OS=Camponotus floridanus GN=EAG_15254 PE=4 SV=1 -----DILEPEMEKLAEYLQVEFNKFYNEATVKVVNCPDLRKAPFHLVAPGLCGNTALLEVGSLSNLFPFPRMEKKYDFISFLEtsGRSNDDNFIIGASLYPSSNGHMGELIMNASFspLDEEGMRVKNRSYVAFLAqDHTGENVKLDILNDYNRVKCFLHGNFFISEGKPGRVLEIHAKARREDKELTKVIQHTLQKYYEATstLVGLGGTFVVHNGLVRHHLMPDIGQISleNCSDESRIRNWVKTRILTTPLVAVGTIVNKSSF-------------------------------------------------------- ->tr|A0A1B6G5D9|A0A1B6G5D9_9HEMI Uncharacterized protein (Fragment) OS=Cuerna arida GN=g.40942 PE=4 SV=1 ----KPLYCPSLTDAAEALKDGLSETFETVEVSVVDCPDLTQKPFSLASQGLGGSPTILEVGGVPFLMPLVDRSKVYDFKDMNKVTGVNPAFIIGAGAGPFTYAGVNCELVANLVVKDGeVR-QLSQIAKLKDESKGDEFVTETL--QDSVSSFALLANLFVSEGKPGKVIRVHCANRKGKSDFVTAARDSLLKGFPGKAIGVGGTFLVNGSKVKQHIMA-DFTTTPLDSEEKVT-------------------------------------------------------------------------------- ->tr|A0A1S9RUH1|A0A1S9RUH1_9EURO Ester hydrolase c11orf54-like protein OS=Penicillium brasilianum GN=PEBR_10800 PE=4 SV=1 ----HPRDPPPLGELAAIIQRSLLANFASASVSVVECPDLRQPPFYLASSGLSGNPCIADVGGQANLFPRPNFDAKFNLRSLAKDMQMTegeGGFLIGAGAAPFHDTGYNAELAVNLYTPPGpHVgtsdpdvdRVRNGSRIIQVNPDGSS---CCE--PIGSLNCGLMVNLFGSTGDTGPVLKITARARTGDKNFTNCIRLGLADHYGDsRPISLGGVFLLKAGKAKFHIMP-DFPQEddlPFQDrEKLEKNWLTYHDFEAPVICLTVMH------------------------------------------------------------- ->tr|A0A1X7RMD4|A0A1X7RMD4_ZYMTR Uncharacterized protein OS=Zymoseptoria tritici ST99CH_3D7 GN=ZT3D7_G3732 PE=4 SV=1 ----HTLSPPSLEELAQVLSPALKANFKTSSVTVERCPDLRKPPFYLATEGLSGQESVADIGGQPNLFPQPRLECKYSLLEIAKEMEMSgsKGQLLGAGAGPFHVIGMNSELSPNLSWEKS--fdnvnNLTYYTKIEEDHGKPIA---RCE--KSPCADCALMMNLYGSTGNSGPVLKITARTRTGSqKSFTECIRRALFDKYGDaHPISIGGVFVMKTGKAQFHVMP-DFPPAeqlPWTQgSQ-VNDWLTWHEFIAPIVCLTVFH------------------------------------------------------------- ->tr|T1J8W5|T1J8W5_STRMM Uncharacterized protein OS=Strigamia maritima PE=4 SV=1 --------QPEANELQSVLEKGLKNSFEEASVQIIDCPNLEKEPFNLAAKGICGRPTLIDVGGVRNLQPVPMRNKVYNLDELTQMTHNPDAFLMGAGGGPFHVTRVNCEFMANIRTSVT-GHGRNLSYIARLDSETEYKLLQIP----ENRECGLMLNALVCEGTKGKVMYVRAKKRTRDTNFITAMRETLKVAYGNKPIGLGGVFLLQKGNAKLHIMP-DFPIYPLIDEATVNSWLKFYDMHAPLVCLSTFVTHDPlEMDLRIEHTHCYSNHGQGGHYHYDTTPDTVEYMGYFVPCSTLYRIDKPPV------- ->tr|A0A0L7L9M9|A0A0L7L9M9_9NEOP Ester hydrolase C11orf54-like protein OS=Operophtera brumata GN=OBRU01_09397 PE=4 SV=1 ---EKALYVPPLEEVVDVLARGLPDTFETVSVSVVDAPDLTQEPFSLTSPG---DVKLVEIGGPPYLVPLVKRDKIYDLHLLLQHLKRDPGflagagagpwpylgvncerprfsgghggwalavpgsqlrgiliahlkrdpgfragagagpwpylgvncerprlpggrggwalavprsqlrgtliahlkrdpgflagtgagpwpylgvncerprlpggrggwalavpgsqlrgtliahlkrdpgFLAGAGAGPWPYLGVNCEGI--INLSVRNGSVEQGTRIVSVEPVGAakgssGFLQQRLPN--TETRTALLGNYLLSEGKPGK--------------------------------------------AKFHVMP-DFSGTALCSDSDVDGWLHYFELSAPIVNVGTLVTGDLGLDLRVQHFHGFSAHGHGGHYHYDTTPDAAHYEGYFSLAHSVVRIDPPAETHALGRD ->tr|A0A0N1I8F1|A0A0N1I8F1_PAPMA Ester hydrolase C11orf54-like OS=Papilio machaon GN=RR48_02211 PE=4 SV=1 ---TKALYVPPLEEMAdaefcqlienvqdkreliamcvAVLSHELRSTFETVEVSVVDCPDLTQPPFDLQAPGISGNATLVEIGGPPYLMPLVQRDKVYDLAALLRHLRRDP-aLLTGAGAGPWPYIGVNCEGI--INLRMQDGAVRQGTRVVSVQPVGAakgssGYLQRRLPD--AETRTALLGNYLLSDGAPGKVLRVVAKRRVGADNFITAIRRALQARYGERGVGLGGAFVLREGRVKHHVMP-DFSSTALCSDEDIDRWLHYFEMRAPIVHVGTLVTADLGLDLRVQHFHGFSAHGDGGHYHYDTTPDSVHYEGYFTPADTIVRVDAPRDTHAFGRD ->tr|H9J011|H9J011_BOMMO Uncharacterized protein OS=Bombyx mori GN=LOC101745847 PE=4 SV=1 ---EKELYTPPLDEVACVLSNGLTTNFKFVEVSVADSPDLTEPPYYLKSPGLTGDAKLVEIGGPPYLVPQVKRDKIYDLAKLLEHLNRDP-aFLAGAGAGPWPYLGVNCEGI--VNLSVRNGTVDQGTRIVSVHPVGApkgssGYLQQQLPN--DETRTALLGNYLLTEGKPGKVIKVVAKNRTGKSNFITSIRETLKTHYGDKVVGLGGAFVLRAGRGYFHVMP-DFSRAPLCSDAAVDSWLHYFELDAPLTVVGTLVTGDLGLDLRVQHFHGFSGGgggaGAGGHYHYDTTPEDVHYEGYFTVASSLIRVDPPVETHTFGRD ->tr|A0A1W4XLR3|A0A1W4XLR3_AGRPL ester hydrolase C11orf54 homolog OS=Agrilus planipennis GN=LOC108745268 PE=4 SV=1 ---YKPLYKPPLQELADVLNQNLTYNFAEVHAEVVDCPDLRKEPFTLASEGLGGNPRVVEIGGVPYLAPIAQLNKVYDLKDIERFSGL---ksaFIVGAGAGPHPYAGVNCEGI--INMNVKDGKVEQQTRISKVVPSDGSQVQEILPN--SETRIALLANLFYSEGKPGKVLKVHVKKRIGSDDFVTSIRETlAKRYFDDKIIGLGGTFLLKEGKAKQHVMP-AFSKTPLNSGKDIDNWLKFYNMSAPLIAVGTLETGDPGLDLRVQHFHSFSHHGEAGHYHIDTTPETVEYLGFFNIGEYVYRVDAPAVSHSFGRD ->tr|A0A1W4VTT6|A0A1W4VTT6_DROFC ester hydrolase C11orf54 homolog OS=Drosophila ficusphila GN=LOC108100296 PE=4 SV=1 ---EKPLHVPCLSEIQRVIQGALSENFKTVDVSVGPCPDLEEPQFGLVESGLGGNPTLLEAGGPPYLRPLVQREKLYNLKEITRKAQGS--geiFAIGPGAGPWPIRNSNCEGI--FNFSLSEKDElKQGSYTATV-----rgdqeECVLERIPE--TEARCALILNLFLSEGKPGEVLRISAKQRTGKENFVECIRKGLEQHFGDKVVGLGGIFVVKKGCVHQHVMR-DFSKTPIHTQEQIQEWLKFYEMPAQLNAVGTLVTKDLGLDLRLQHFHSFSFENWGGHYHYDTTPDVVEYEAYLNVAERVIRVDRPVVTDQLGRD ->tr|A0A182FFU6|A0A182FFU6_ANOAL Uncharacterized protein OS=Anopheles albimanus PE=4 SV=1 ---EKPLHMPTLQELRDVLAVGLKSSFTTVDVEVVECPDLTRAPFHLAGAGLCGSATLVEIGGPPYLLPTVDRSKLYDVIEVSKRALphganSPKSFItIGAGAGPFPLVDSNCEGMFNVHY-SPPGTIVSESHLAIVAPDAGTMSIRKIPN--TETRCALLANLLVSEGKPGPVLKVHCKRRTGNKDFIASIRTCLADRYGDdRTVGLGGVFLLVEGKAKQHVMS-PFSATPIHTEEQLNEWLNFYDMPAPLINLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPDAVEYEGYFVVGERIVRVDKPVVTHKFGRD ->tr|A0A182MQZ2|A0A182MQZ2_9DIPT Uncharacterized protein OS=Anopheles culicifacies PE=4 SV=1 -----------------VLAVGLKSCFATVNVEVVECPDLSKAPFHLAGCGLNGTPALVEIGGPPYLLPTVDRTKLYDVVSIAKRALhdDQKAFIaIGAGAGPFPLVNSNCEGMFNLHY-SPPGIVMSESHLAMVSPERE-VIVRKVPN--TETRCALLGNLLVSEGNAGPVLKVSCKRRTGNKDFIASIRTCLEDRYGEKTVGMGGVFLLQAGKAKQHVMS-PFSTTPIHTEEQLNQWLNFYDMPAPLINLGTLVTNECDLDLRLQHFHSFSTHGHGGHYHIDTTPEVVEYEGYFVVGERIVRVDKPVHTHKFGRD ->tr|A0A0A9XUG4|A0A0A9XUG4_LYGHE Cytoplasmic tRNA 2-thiolation protein 1 OS=Lygus hesperus GN=GF12710 PE=3 SV=1 ------LDTPSLAEVRDVLARDLKKTFDYVDVQVVDCPDLTEEPFFLAGKGLGGETSLIDLGGPPYLLPLVKRDKVYDFKQLVKQLKVTPSLLMGACAGPWPYFGKNCEGVCNVLVDGDN-YFKSCSYVGKVTDGDEklECLPIPDSE----TRFALMANLYCSQGKPGKVLKVNCKKRTGKKDFITAIRTGLAAGFPNKYVGLGGAFLLKEGRAKQHVMR-DFSKTPINTEEELNNWLTFHDMSAPLVAVGTLISNEvPDFDLRVQHFHSFSKHNEAGHYHYDTTPETVEYLGYFNVAERLHRVDKPKQTHQLGRD ->tr|A0A1J1I839|A0A1J1I839_9DIPT CLUMA_CG009848, isoform A OS=Clunio marinus GN=CLUMA_CG009848 PE=4 SV=1 ----KELFVPEMETLCSVIETGLKSNFSDVSVSVVDCPNLSQAPFHLASSGLGGDATLVEFGSPVYLLPLVNKSKIYDIVELLRNISSyesKEFFTCGAGAGPFPIFNQNCEGMLNIRVGSDGTL-KNETHVARIVP--GGVELSKVPD--QETRCALLGNLYLSEGKAGKVLKVTAKRRTGSENFISSMRLALAEYFtDDKTVGLGGTFLIKEGKAKQHVM-DEFSKVPLYTEDDVNKWLTFHEMSAPLIAVGTFVTNEADLDLRLQHFHSFSKHGEGGHYHYDVTPDTVEYEGYFAVGRRIIRIDKPEQ------- ->tr|W2TIQ2|W2TIQ2_NECAM Uncharacterized protein OS=Necator americanus GN=NECAME_17820 PE=4 SV=1 -----------------------------------------------------------------------------------------------------------------------------------------------------------MGDLGVSAqPGPGEVVHIKCSQRIGKESFPQCIQESLARHYGQSCVSLAGIFALLRGNASVHIAP-DFPDKSFRSREEFDQWLQIFNLSAPLICASVINSYDPGFGLRMHHTHCYSSHNDAGHFNNDITPETVEYEGWFTAAEKIYRID----------- ->tr|A0A1E1WGP1|A0A1E1WGP1_PECGO Uncharacterized protein (Fragment) OS=Pectinophora gossypiella GN=g.19230 PE=4 SV=1 -----------------------------------------------------------------------------------------------------------------------------------------------RRLPPTETRTALLGNYLLC-dGRPGKVIKVVAKKRIGESNFITAIRETLKNHYGEKVVGMGGTFVVRAGRVKHHVMP-DFSAAPLCSDSDVDAWLHYFEMRAPITHVGTLVTGDHGLDLRVQHFHGWGEHGDGGHYHYDVTPASVEYEAYLTPAASVVRVDAP--------- ->tr|A0A1Y3ANJ6|A0A1Y3ANJ6_EURMA Ester hydrolase C11orf54-like protein (Fragment) OS=Euroglyphus maynei GN=BLA29_006393 PE=4 SV=1 -----------------------------------------------------------------------------------------------------------------------------------------------RLDKCKYPEFGLLGNLFISEGKPGKVIEIIVEKRLGKENFPESIQKILRENFPNKPISLGGVFIIEKGRTKLHIMP-DFSPEPLRTNDDVDKWLRYFDMDPPLICLTTLHSIDPGLDLRMEHTHCFSDHNQGGHYHYDITPDIVRYTGYLQIVEAIYRIDRP--------- ->tr|A0A0G4IS31|A0A0G4IS31_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_006131 PE=4 SV=1 -----DLFAPALDDAVAPIAAFLRDRYEHASVEVVECPNLLS--WGLAMPGLGGQPRLVDVGGVPNLLDPAHQDKSFAIGDILDCAGLPTGCVLGAASGDAAWAKGNTELMPCASRH------TCRSKSARVG-ADGRCVLDEYDWDRVGF----LANLFVCQGVPGPVLEVRARGRRLPEdhsdNFVGNIRGALLQRFPGRAIGLGGAFTMKKGLFKAHVMPD-FKDTVMVDGPEVQEWLKYYEMGPGATFLSTMLTQDPTpdgaLNLRLEHTHFFNQTaGEGGHYHYGTS-LDVDYVGYFALAERVYRMEN---------- ->tr|A0A0P8YN63|A0A0P8YN63_9PROT Uncharacterized protein OS=SAR11 cluster bacterium PRT-SC02 GN=JI56_00575 PE=4 SV=1 -----KFNNPSLEILAEALKKGLKANYQEVTVEIINCPNLRE--WNCPSEGISGNERIIDVGGEPYMHDKQFIGTEFDYEEIAKNIGSEKSYALGAGSGAMSCLGGHCGELIInenLITN------ESNSIIAQVN-KNKECVTKKYTEKKHGG----LANIFFSDGKIGKVIKIKLKKRIGKQgs-LPQAMRSALFeniIIQKNRHVALGGVFRVLHGGVKSHVQPD-YEDIKYEYyDSklmkCTKDFLQFYEpVGPKLQCYSVLWTGDPTggdLNLREsgEHTHFHSyNNkPEAGHYHFDVTPNDIEYECYFNIAHEVFRVNN---------- ->tr|A0A1C2AY87|A0A1C2AY87_9PROT Uncharacterized protein OS=Pelagibacteraceae bacterium GOM-A3 GN=AKH20_00875 PE=4 SV=1 -----IFKKFKLEEISNALEKGLSKNYDSVKAEVIDCPNLRN--WDCPSEGMSGNQRIIDVGGEPYMHDPKYLGTEFDYFEISKMIGSERSYALGAGSGAMSCLDGHCGELVInenFITK------ENKSLIARVG-KDKQCIVEDYTASKHGG----LGNVYYSDGVKGKVVYLKIKKRIGKQgs-LPQSIRAVLSenlKIGNKDHIALAGVFRVLNGKIRSHVQPD-YKDIKHEYyDPelmkCTKDFLQFYEpVGPKLQCYTVLWTGDPTggeLNLREsgEHTHFHSyEHkNDAGHYHFDVSPDEIEYEGYFNIAQEVYRVNN---------- ->tr|A0A1J1I839|A0A1J1I839_9DIPT CLUMA_CG009848, isoform A OS=Clunio marinus GN=CLUMA_CG009848 PE=4 SV=1 ----KETHKPSLDEIRNVLEEALKKNFNEVSVEIVDNPDLKSEPFYLASSGISGNPLIIEYGNDDYLLPLVDKSKVYNLIPTIREIetyKEKNFYVCGAGAGPFPLYDQNCEGiynMKVFKNG----TIDNQSHIARTQ---G-SGTETLKLPNNETRAALLGNLFLSEGNDGKVLKVIAKNRTGEENFISAMRLGLSEKYSeDEVVGLGGVFVMKKGIANIHVMD-RFSENPINTDEELNNWLTFHEMPAPLIALGNFVSHQTDFKLRYHHFHCFSKHNHGGHYHYDVTPDIVEYEGYFNIAERIILIDKSF-------- ->tr|B4H5I4|B4H5I4_DROPE GL16084 OS=Drosophila persimilis GN=Dper\GL16084 PE=4 SV=1 --------------------------------------------------------------------------------------------------------------------KPLHVPPLpelqnviQGALRGNFAPSWRACVLEKIPHT--EPRCALLLNLFLSQGAPGQVLKISAKQRTGEQNFIECIRKGLEDHYGDRVVGLGGIFLIKKGAVHQHVMR-DFSSTPIHTDEEVNEWLKFYDMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPLSTHKVGRD ->tr|A0A1B0FJ72|A0A1B0FJ72_GLOMM Uncharacterized protein OS=Glossina morsitans morsitans PE=4 SV=1 --------------------------------------------------------------------------------------------------------------------KSLHKPPLeelqnglGGCptllelggapyllpkvqkdklydikaicrksmgegkilavgagagpyplrttncegifnlsisaqdeikngsYTAKITGLQEDCLLEPIPDT--ETRCALLLNLYVCRGEPGPVLKITCKKRTGHMNFIECIRKGLYEKYQDKC------------------------------------------MPGTLHAVGTLVTHEHDLDLRLQHFHSFSRTKWGGHYHYDTTPDTIEYEAYFNVAERIVRVDKPKTTHKFGRD ->tr|A0A158P7C4|A0A158P7C4_ANGCA Uncharacterized protein OS=Angiostrongylus cantonensis PE=4 SV=1 ----IETLKPSNSELLPIVESALKSNFKDVTVEVGPCPgkivcvreqqlpfpvvvDLSVEPFSMTSSGFGQNLVIAEVGGPGNLFPKINKEKEFDLKEICNTCQSPFSFVFGPGAGPWKVVGRNCEMVADAnfatakvATK-----------IASLPPgyS-PPYKMGV----IDSPKFSLMANLAVSEPGPGEVLHCKCSVRIGKDNFPETIRKALAKHYGKRCVSLAGIFLLGEGEAKLHVMPD-FPGCQFSSTEEVSL------------------------------------------------------------------------------- ->tr|F1LEY2|F1LEY2_ASCSU Ester hydrolase OS=Ascaris suum PE=2 SV=1 ----IVLKTPPLEELSSILCAELKKNFVDVSVDIVDCPNLRAPPFRMSGAGIGNDLRIGEVGGIGNLFPSPKTDKFFNLKKICETCEMPKAFVFGPGAGPFHIVGNNCEMVADAdfttdhqnnvATK-----------VSRVVPNGKGYEMST----IDNADFVLMANLAISDGFpAGKVLRVHAAKRNGEMNYPGAIRKALIGYYDGqrMAEVFRN-----ESAISMCIGIA-FE------------------------------------------------------------------------------------------- ->tr|H2VJ38|H2VJ38_CAEJA Uncharacterized protein OS=Caenorhabditis japonica PE=4 SV=2 ----IENHVPSLDELKEVFIKSLTENFETVTVDITTCPDLSKPPFNQTSSGFGENLRIAEVGGPGNLFPGFHIDHQFDITTIGKVCELPEASVFGPGAGPWPVVGQNSEMVADVnlktgrsATR-----------IAEIKPgnGNKKYLQRS----IDQPKFSLMANLALSNADkSASVVHFKVSVRKGEKNLTLCIRDGLQKHFGDK-------------------------------------------------------------------------------------------------------------------- ->tr|A0A1F5LXL7|A0A1F5LXL7_9EURO Uncharacterized protein OS=Penicillium arizonense GN=PENARI_c001G10941 PE=4 SV=1 ----HPRDPPPLDELAAIIERSLLCNFSTASVSVVQCPDLRHAPFNLAGSGLSGNTRIADIGGQQHLFPQPVLDAKYSMLSLAKDMEMSsaKGFILGAGAAPFQDIGQNAELAPNLsweaknntsdLTD-----------TNSLNVesGtrvikisqDNSPKCEQ----LPSTNCALMINLFGSNGETGAVLKISARTRTGEENFTNCIRNGLRDAYGDsRPISLGGAFLLKSGSAKFHIMPD-FPAEDQLpfrDRQQLEK------------------------------------------------------------------------------- ->tr|A0A1V6PWG5|A0A1V6PWG5_9EURO Uncharacterized protein OS=Penicillium antarcticum GN=PENANT_c028G11198 PE=4 SV=1 ----HLRDPPPLDDLATVIERSLLSNFATASASVVQCPDLREAPFNLAGSGLSGNARIGDVGGQQHLFPQPVLDAKYSVLSLAKDMEMSptRGFILGAGAAPFQDIGQNAELAPNLswkandsasdFTD-----------KSSLSLenGtrvikinqENSPKCEK----LPSTNSALMINLFGSDGETGPVLKVSARTRTGEENFTNCIRNGLRDTYGEsSPVSLGGAFLLKSGSAKFHVMPD-FPPEDQLpfrDRQQLEK------------------------------------------------------------------------------- ->tr|A0A147B707|A0A147B707_9ACAR Ester hydrolase c11orf54 homolog (Fragment) OS=Carios mimon PE=4 SV=1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPVGLGGVFLLKQGKAKLHVMP-HFSTKPLTTADDVNGWLKFFNMSAPLVCLGTLMSHDPGWDLRVEHFHCFSDHGEGGHYHYDVTPEEVEYLGYFSVAEYMYRIDAPDVTHNIGRD ->tr|K7I0V9|K7I0V9_CAEJA Uncharacterized protein OS=Caenorhabditis japonica PE=4 SV=1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------XVVSLAGQFIIHTGKAKLHVMP-DFPGCPFADNAEVDKWLNYFEMDAPLVCATVMHSSDPGHNLRLEHTHCYSDHGDAGHYHYDVTPLEVSYEGWFAPASKVFRIDEVSGR------ ->tr|S4P157|S4P157_9NEOP Ester hydrolase OS=Pararge aegeria PE=4 SV=1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MP-DFSATPVRTDAEVDAWLHYFDMRAPITHVGTLVSGDLGLDLRVQHFHGFSQHGDGGHYHYDTTPGEVHYEGYFALAGSVVRVDAPAETHAVGRD ->tr|Q5AY31|Q5AY31_EMENI Uncharacterized protein OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) GN=AN6799.2 PE=4 SV=1 --------PPPLSELGSIIARALQQNFAHASASVTQCPDLRKPPYGLAASGLSGNPRIADVGGQANLFPSPNFNAKYSLLSLARDMEMsaERGFVLGAGAAPFQDIGHNAELAPNVAWQAreGVKELDlgNPDCVDIVNETRIVevVAGEVDSVSCWrapSANCALMVNLFGSSGLPGPVLKITARGRTGPANFTSSIRAGLLAAYGDsHPISMGGVFLLKAGKARFHVMPDFPAPedLPFKDRRvLEQEWLKYHTSEAPVVCLTVFHSADPeGLQLRMEHTHCFDLEGcrKGGHYHYDLETDnggEVEYEAYLNVAEVVYRIDRP--------- ->tr|A0A136IYY9|A0A136IYY9_9PEZI Uncharacterized protein OS=Microdochium bolleyi GN=Micbo1qcDRAFT_196324 PE=4 SV=1 ----YPLSPPSLSALAAVLQPALSRNYAHCSVSVSPCPDLRQPPFHLAAQGLSGDEKIAEVGGQSNLFPSPDLSAVWSLPEIARDAmgmDAARGMLLGAGAGPYRDVGQNSEWAPCYSWEDN--KVRNESRCALVRKDTGKVEVR----KQDSLGCALMCNLFGSRGEPGDVLRITARRRTGDAaSFTECVQAALREAYGDAegstVVSLGGVVLIKKGLAKYHVMPDFpdEKDRPFRDLDQLMKWLTWHEYRGPIVGLTVLHSADPGGkvGLRLEHTHTFSATGEdaGGHYHYDIEDeggEDVEYEAYFNTAK----------------- ->tr|Q0CB59|Q0CB59_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_09075 PE=4 SV=1 --------PPALEELAAIIQQSLQSNFETASASVVQCPDLRQPPFKLAAPGLCGEACIGDVGARGNLFPRPNLNAKYSLLSLAEDMKMSteKGFLIGAGAAPFQDIGQNAELAVNLswQGRSDGAEFNEPSSLVVENKTHVVRISQDSTSTCKtttSTNCALMMNLFGCHGEAGPVLKVTARSRRGKDNFTNCIRHGLYAAYGDtRPVSLGGVFLLKSGKAKFHIMPDFPPedQLPFPDREYmEQRWITYHVFKAPIVCLTVLHSADPeGLGLRMEHTHCFEieGHRQGGHYHHDINdgGDEVEYEAYLNAASLLYRIQ----------- ->tr|A0A016RWU6|A0A016RWU6_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0351.g3242 PE=4 SV=1 --------KPSNNELRSVIETILWKNFKNVQVEVASSPDLTAAPFRMTSNGFGKNLVIAEVGGMGNLYPDLHKEKQYDIQEICEKCGAPKAFVFGPGACPSRVIGAGELVADA--NLSENKVTSK------VTTLVKN-HFLKYKTKIiNSTKFSLMGNLVVSEQpGPSEVVHVKCSERTGEDSLPGCIRKGMAEHYGQSCVSLAGIFLLLRGKADVHIIPD-YPEKPFNSMDEVEKWFQIFNVSAPLVCASVLHSYDPGYKLRIQHTHCYSDHDDAGHFYNDTTPKIAEYEGWFTAAEKIYRIDE---------- ->tr|A0A068X426|A0A068X426_ECHGR Ester hydrolase C11orf54 protein OS=Echinococcus granulosus GN=EgrG_000294200 PE=4 SV=1 ------------YDVCSTLECYLTPYFGHLTAKVVECPNLNQRPFYLGRSGICGDSTIANVGSLDYLLPCADPSRLYDIMDITKYTGHCQGMILGGGVGPFQCYKKPCEVSTEITYST-RGLQCNRSLIGFCSKECGSP----SSERASNTLLSSLGQIFITEAMPGKVVEIVAHKRIGGPSIIDLMQAALYDKFSkqELPMALGGVFYLQNSGAQASVLC-ELPQEPYHTFPCLKKYQTSFNIDGPIIGVGTVLSHDPkKMGFSMASFYCWNAsRLLTGHFENDICPEKATYTVYLTPAKKLYRQDKPVHN------ ->tr|A0A0R3WZJ8|A0A0R3WZJ8_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1 ---------------VEVFRNRLKEYFKSTKVNVVPCPDLTSPPFGLLRPGLAGQSVVCDVGSMSYLLPVADTSKKYSFDQVVESSGVHSGHLLGAGGGPFFTHGKTCEMAASLQYEN-DKIISNSTLHGVYGEQTGTP----QVIKATDNNFGLVGQLLSTEGLPGSVVvcihtiflflslyifwhqviEVDVADRLKEGSVHVFLREALTDAYGklDKPVALGGVFVLTDSRARFHVLQPNFPPHPVDTPARMAEFIKVFEMDPPVLGMGTLISHDPyGIDLKLEHFHCYNEaKNLAGHFYWDTEPEKAHYRLYLTVAKGLLRIDPKKKT------ ->tr|A0A0X3PY77|A0A0X3PY77_SCHSO Ester hydrolase C11orf54 homolog OS=Schistocephalus solidus GN=CK054 PE=4 SV=1 ------------VEIARELKRGLQPLFGFVDAKVVECPNLTRKPFNLPRSGISGENTIACVGSHDYILPSISCRKQYDLMDVANACKVRAGEILGGGTGPYPTTGHPCEMVAELCYCN-GSISCNRTLHAYSDKSGSAP----NLIKATDTKFHSSAQLFVSEGNEGWVIEVIAKRRLCEGSIGKFLHQALQSRYGrgDEPMALGGVFLLEGSGAKYHVLS-ELPNEPYHTFPDLKSYLKCFEMKAPIIGMGTVLSHDPnDLGLHMHSFHIYNVeRNVAGHLETDTDPEAASYRIFLHPASHICRMDKPVY------- ->tr|Q0MQZ2|Q0MQZ2_TALMA Mitogen-activated protein kinase OS=Talaromyces marneffei PE=3 SV=1 ----ISRSPPTLSELAEKLQGSLSANYERSSVTVVPCLDLREPPFLLAHEGLSGDEKVADVGGQTHLYPRPMRDKTYALISISREMEIEvgesheQVMIIGAGAGSSDIVGQNCEMAINFGWRygggggggggggggvPQGSWRHNGGRYVKIEPGTDSVLLEKTDSA--RWWFGLMGNLFASDGGPGDVLKITARKRVGEEgSFTECIRKALHAAYGDSQIvSLGGVFVIKSGKARYHIMPDFPpEELPFRDRQRFNDWLTYHDFKGPMTCLTVLHSVDPDkkLGLRMEHTHALSTVGEnaGGHYHYDVEEekEEIEYEGYFNTAKALYRIDKPEF------- ->tr|A0A1Z5TUE2|A0A1Z5TUE2_HORWE Peptidylprolyl isomerase OS=Hortaea werneckii EXF-2000 GN=BTJ68_00352 PE=4 SV=1 -------SPPTLGEICSTLRPALKANYSDSSIEIVTCPDLTAPPFHLASQGLSGKESIADIGGQAHLFPRPLKEKKYSLVDCAKSMGMSqqRGLLIGAGAAPWHVIGQNAELAPNVSWEGsmdEESRVRNQTFVTRVESHGGQVRC----ERLPSMEFALMMNLFGCEGVTGDVLRVTAKGRRGQqGSFTECLRQALHAEYGGeRQVSLGGVFVMKKGKAVFHVMPDFPpeEALPFPSHDAVNEWLTFRQFSAPIVCLSVLHSADPEkLGLRMEHTHCFSTdKDEGGHYHHDILPD----------------------------- ->tr|A0A074ZFU1|A0A074ZFU1_9TREM Uncharacterized protein OS=Opisthorchis viverrini GN=T265_14086 PE=4 SV=1 --------CPGLGNLTGFMS----GCFSKVACQVVDCPNLKDPAYALNSAGLCGSETLCDIGSFDYLLPVPNKEKRYDLLDAFSLSHVGSGFIMGAAAGPHFVAGINSELVANLS-ATDGKVLQNGSYCGSYDAKN-NLPVSTLSET---SLFAMVGQMFLCEGKPGKVIQLTVSGRTREGKFDALLREALASKYGalDRPVGVGGVVVQETGKCLFHVLP-EFCEEPLDTPEKLKQWLKFFEMEAPVVAVGTALSHDPQkWKIRLEHFHCFNRDRtKSGHCHFDSDGPTASYTAYLVPGKRLLRVDPPK-------- ->tr|A0A0R3U295|A0A0R3U295_9CEST Uncharacterized protein OS=Mesocestoides corti PE=4 SV=1 ----------------------LAPYFRHLTTKVVECPNLGAKPFYLGRAGISGDATLANVGSYDYLIPCADHGKMYNFVDVARYSGISFGMVLGGGIGPFQAYQKP----------CECEVP--------------------ISERASNNFFSATGQFFITEATPGKVIELKAAGRVNCHNIFDLIQKALYNKYSksSSPVALGGVFFLQNSAVEVNLLN-DLPKEPYHTFPCFKEFQTTFKIEGPIIGTGTIVSHDPnNQDLVTQSFYCWDTeKQLTGHFENDICPDMANYTVYLYPARNILRLDKPY-------- ->tr|A0A0R3U4D3|A0A0R3U4D3_9CEST Uncharacterized protein OS=Mesocestoides corti PE=4 SV=1 ----------------------IKDHFKSVNVRIVPCPDLKASPFRLLCSGLSGQNIVCDVGGMSYLLPVPDKTKMAANVRFEDSK-ISSNSTLHG------VYDES------------TRSP--------------------QVLAATDNNFALLAHLLATEGLPGDVIEVDASGRLKEGAPYVFLREALTSAYGklDKPVALGGVFMLTGSKGRFHvlfieaavplLQP-DFPDHPVDSPSRVAEFLKFFEMEPPVMGMGTLVSHDPfGIDLKLDHFHCYNEkRDLAGHFYWDTEPQTAHYKFYLTVAKSLLRIDPKP-------- ->tr|A0A1L1ST86|A0A1L1ST86_MOUSE Uncharacterized protein OS=Mus musculus GN=4931406C07Rik PE=1 SV=1 -CSEFSFHMPSLEELAEVLQKGLTDNFADVQVSVVDCPDLTKEPFTFPVRA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|C5M1Q2|C5M1Q2_PERM5 Putative uncharacterized protein OS=Perkinsus marinus (strain ATCC 50983 / TXsc) GN=Pmar_PMAR027336 PE=4 SV=1 ----------TIDEVADALRDGLAKVFKKIDVDVVDCPDLRQAPYLCskPGLGSPGKGSVVDCGGCALLYPKVDITKEYDMRQIASIVDnythvgggdeeayppssaestvagsptersnslpshhTPQAFhILGAGACAYSVTGQNGELA--INCADEGDPHTACGI---V---CEDSLPEK--KNYHSYLSGPLCNVFKCSGAPGKVLRVHAAARMDPEvgsDIVETMKSILETAFPRDVLGLGGVVLVKKGKVMIHVMH-DFTVKPIRSQKFIdSEWLRMKEADTPFTNYTVFVTNPPAtLDLRPSHTHGFNDK-VAGHYHYDTTPLRVDYECYLQLADNIYRVDRAS-------- ->tr|A0A016S224|A0A016S224_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0312.g2179 PE=4 SV=1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVRTQKVDKWLRFFTMKAPLVCASVFHSYDPGHKLRLEHTHCYSEHGDAGHYHYDTTPETVVYEGWFTAAEKIYRIDE---------- ->tr|A0A1B6FX27|A0A1B6FX27_9HEMI Uncharacterized protein (Fragment) OS=Cuerna arida GN=g.40946 PE=4 SV=1 -------------------------------------------------------------------MPLVDRSKVYDFKDMNKVTGVNPAFIIGAGAGPFTYAGVNCELVANLVVKDgEVR---QLSQIAKLKDESKGdeFVTETLQDSVS--SFALLANLFVSEGKPGKVIRVHCANRKGKSDFVTAARDSLLKGFPGKAIGVGGTFLVNGSKVKQHIM-ADFTTTPLDSEEKV--------------------------------------------------------------------------------- ->tr|A0A1B0DGT9|A0A1B0DGT9_PHLPP Uncharacterized protein OS=Phlebotomus papatasi PE=4 SV=1 ---QKELFVPDTQELKEVLTLGLKKNFEEVSVDFVECPDLSKEPFNLASSGLCGNPTIIEYGGAPFLLPLVQRDKLYDLDEICQKICRFrnisEYLAVGAGAGPYVLCNTNAEGIFNLKR-NADGSIVSKSHLALVNAEKN-CERRSIP--SSETRSALLGNVYLSEGKGGQ-------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|T1GJ03|T1GJ03_MEGSC Uncharacterized protein OS=Megaselia scalaris PE=4 SV=1 ---EKSLHVPELDEIVQVLQSALSRNFQEVTVEIVDCPNLTAEPYSLVCEGLNGSLTLMELGGFATLLPLEDKGKVYDIVETSRKIMKGkDLAIIGTGAGPVSLEKSNCEIILNMNI-PLKGNLENKSIAIRINEDDE-ISLDPIN--D-QQIFSYLVNIFLCEGKSGK-------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A016S2V2|A0A016S2V2_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0306.g1982 PE=4 SV=1 ----INTLKPSNHELRSVIEAALWKNFKNVQVEVEKCPDLTAAPFHMTSPGFGRNLVIAEVGGWGNLFPNLHKEKLYDIKEICNTCGAPKAFVFGPGGCPPSAVGVNGELVADANL-S--ENKVSSKVTIQLDHY-T-SPYKTLF--VNSTKFVLMGNLAITPEPGP--------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A0R3PRG0|A0A0R3PRG0_ANGCS Uncharacterized protein OS=Angiostrongylus costaricensis PE=4 SV=1 --------------------------------------DLSVEPCSMTSSGFGQKLVIADVGGPGNLFPKIHKEKEFDLKEICKACQSPFSFVFGPGAGPWKVVGRNCEMVSDANLTTAKVaTKIASLPPGHSPP-YKMDVID--S-----PKFNLMANLAMSEPGSGEVVHCKYSVRIGKDNFPETIRKALVKHYGES----------------------------------------------------------------------------LGHYYYDTTPDTVAYEGWFTAAEKIYRIDE---------- ->tr|A0A0N4X8W7|A0A0N4X8W7_HAEPC Uncharacterized protein OS=Haemonchus placei PE=4 SV=1 ----------------------------------------------MTSTGFGRKMVIAEVGGPGNLFPVIHKEKDFDLKEICNGCEAPSSFIFGPGAGPWQVVGRNCEMVADANFSSSKViTAIC-------------HVIS--S-----PKFSLMANLAVSaEPGPAEVVYCKASVRTGKDNFPETIRKGLAKHYGNKCVSVAGVFMMLKGEAKLHVMPDFPGCNFSSREELEKQWLRFFTMRAPLVCASVFHSYDPGHKLRMEHTHCYSNHGDAGHYHYDTTPDTVVYEGYFTAAEKIYRFDE---------- ->tr|A0A0N4YTH1|A0A0N4YTH1_NIPBR Uncharacterized protein OS=Nippostrongylus brasiliensis PE=4 SV=1 ----------------------------------------------MSSNGFGKNISIAEVGGMGNLFPRLHKEKEYDIKEICELCDKKSAFVFGPGACPKSVMGTTGELVADV-------aSKVTNLVNNHSSP-YKTCEID--S-----PKFNLMANLAISeQPEPAEVGNLTV--RVDGSDVPEKL-----------WPE----------------------------------------------------------------------GNLERHYYNDVSPKTVTYEGWFAAAERIYRIDE---------- ->tr|A0A016S202|A0A016S202_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=Acey_s0312.g2181 PE=4 SV=1 --------KPSNAELRSVIEDALKTNFKNVEVDVTTCPDLSAAPFSMTSNGFGRKLVIAEVGGPGNLFPNLHKEKEFDLQDVCKECHAPSSFVFGPGAGPWPVVGRNCEMVADANFASSKVATKIASLvEGHSTPYK-------MS-IIDSPKFSLMANLAVSgEPGPAEVVHCKCSVRVGKDNFPETIRKGLAKHYGKMCVSLGGVFLMREGEAKLHVMP-DFPGCPFKAREEVCA------------------------------------------------------------------------------- ->tr|R7THP4|R7THP4_CAPTE Uncharacterized protein (Fragment) OS=Capitella teleta GN=CAPTEDRAFT_97025 PE=4 SV=1 ------------PNIASVLQDGLSRNFGQVEVSVVDCPNLTQEPFGLACEGLGGHPRLADIGGVPNLVPLAQKKKViFDLSKVPEWTELPDAFMLGAGAGPRHVEGIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A068XCH7|A0A068XCH7_HYMMI Ester hydrolase C11orf54 OS=Hymenolepis microstoma GN=HmN_000758700 PE=4 SV=1 ------------------------------------------APLVFKPARLSGQNVVCDVGSMKYLLPVIDKSKRYSFDEVAELSKIIHGQLLGAGAGPFFIHNKSCEMAANV-EFSDSKIISNSTLHGVYNET----TYEPEVIRATDNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSAYVFLREALTSAFGKlaKPVALGGVFALNDSKARFHVLC-GLPDHPVDTPEKVAAFVKHFEMEPPVLGVGTLVSHDPyNVDLKLEHFHCYNEaQTLAGHFYWDTEPEKAHYRFYLAVAKNLLRIDP---------- ->tr|A0A0R3T6Y0|A0A0R3T6Y0_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1 ------------------------------------------APFKLNLSGLTGQNVLCDVGSMKYLLPVPDKSKRYSFDKVAELSKVVQGQLLGAGAGPFFTHNKSCEMAANV-KFSGSKVISNSTLHGVYNET-------PEVIRATDNNFALLAHLLSTEGLPGSVIEVDVSGRLKEGSTYVFLREALKAAFSKlpNPVALGGVFVLNDSKARFHVLC-GLPDDPVDTPEKVAAFVKHFEMEPPILGVGTLVSHDPyNVDLKLEHFHCYNEaQTLAGHFYWDTEPENAHYHFYLVVAKNLLRIDP---------- ->tr|A0A1I7XMR5|A0A1I7XMR5_HETBA Uncharacterized protein OS=Heterorhabditis bacteriophora PE=4 SV=1 --------------------------------------YLSKAPFNMTSRGFGNGLRIAEIGGPSNLFPKLHKEKAFDLNEVCATCDAPHAAVFGPGAGPWPVVGVNCEMVADANL-S--QGKVNAIYLTFlilishsvlskvtfvhnlyIQTATKIAYIeenssNKYQTKIIDsTKFSLMANLAVSENdDPSEVVHFKCSIRTGQLNLPETIRRAIAEHYTDKPVSLAGLFILHEGEAKLHVMP-DFPSCPFNNTDEVI-------------------------------------------------------------------------------- ->tr|A0A0R3SZD7|A0A0R3SZD7_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1 ----YGVHEVSMEEVAKILQNGLKDCFKEVRVNVANCPDLTKAPFRLSLAGLSGQNVVCDVGSMKYLLPVADKSKKYSFDKVAELSKVIQGQLLGAGAGPFFTHNKNCEMAANVN-FSDSKVIsnstLHGVYDETTNKPE--------VIRATDNNFALLAHLLSTEGLQGSVS------------------------------------------------------------------------------------------------------------------------------------------------ ->tr|A0A0J7NBA3|A0A0J7NBA3_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_10415 PE=4 SV=1 -----------PDKLAHVLEDGLKRTFVNVSVKWVECPDLTQEPFNLAAPGLCGKPALMEVGDLSYLNPNPRKDKIYHINPILKF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A0J7KEV3|A0A0J7KEV3_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_11667 PE=4 SV=1 -----HLNLPDLSEVKNVLEPALREYFNEANVSVVPCPDLRESPFHLAAPGLSGETIIMKMGGTEFL--WI-------------------------------------------------------------NPT------HN--------------MDKSCNGDPGYVLKVNAKGRRTNVNFPTAIQTGLQRRYEpNDFIGLGGTFVIKNGIVRNRLRCP---SLDLNSPSEL-----IHHTSTPLVAVGTILSRKTHtsyyfeeglFEGnaeptillhqlqesefetEVFHTFACNRVDVGGHFLNDFSPLDTEYEGYFNLATKFIRVT----------- ->tr|A0A0J7K1W2|A0A0J7K1W2_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_18048 PE=4 SV=1 -----SINTATLKDVRDVL-YNLREYFNKFEIDVGSCPPLTARPYNFDFNGLSGLNILEQNFPMEKMT-NI-------------------------------------------------------------TPLDESdpvrpiRLHTK--------------YKFFTEDRPGMVLEMYARGRKTNQSIITLMQNILHRRFSh--KMGLGGILIVKGGQLLQYNPK-----FTCEATYH------HIKCDSEITCSGAIVNDPVQilghhdglLmttnrymfDI--------HSEHGNGFFVNDITPKETEYYGIFNVADAVCRW------------ ->tr|A0A0J7K5S5|A0A0J7K5S5_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_15835 PE=4 SV=1 -----SWNSATLKDVRDVL-YKLHDYFDHFEIALVACPCLKKSPYNLDFAGLSGNMYIEELKSPVN---ML-------------------------------------------------------------HPNITVpqagpiPFRSN--------------RNFYSDGKPGMVLKIRARGRRTDHSIITLIQSILHKRFSy--KMGLGGVLLMIGGRVARHIPET----FPLVLSER------YLDCNPAVSAICTIVNNPVLflyqeddlPedgdlyylDTnnsptviqn---YESHCFFGNEHGLFVNDVTPKDTEYVGYFNVAEKVYRV------------ ->tr|A0A1A9UK18|A0A1A9UK18_GLOAU Uncharacterized protein OS=Glossina austeni PE=4 SV=1 -------------------------------------KSLHKPPLEELQNGLGGCPTLLELGGAPYLLPKVQKDKLYDIKAICRKSMVG----AGAGPYPLRNTNCEGIFNLSISAQDE---IKNGSYTAKITGLQEDCLLEPIPD--TETRCALLLNLYVCRGEPGPVLKITCKKRTGHMNFIECIRKGLYEKYEDKCV------------------------------------------------------------------------------------------------------------------ ->tr|A0A0C2GJL4|A0A0C2GJL4_9BILA Uncharacterized protein (Fragment) OS=Ancylostoma duodenale GN=ANCDUO_10715 PE=4 SV=1 -------------------------------------KNLTAAPFRMTSNGFGRNLVIAEVGGMGNLYPELHKEKQYDIQEICEKCGAPKAFVFGPGACPSRVVGAGEL-----VADAN---LSENKVSSKVTTLVKDHFLKYKTKIINSTKFS-LMGNLVVSEQPGP---SECSERTGEDSLPGCIRKGMGEHYGQ--------------------------------------------------------------------------------------------------------------------- ->tr|A0A0J7L9H0|A0A0J7L9H0_LASNI Ester hydrolase c11orf54-like protein OS=Lasius niger GN=RF55_650 PE=4 SV=1 ---ETDLFVPEAKGLARTLQNGLRKHFAEATVEWVDCSDLTQEPFNLAAP---------------AFL----------------------------------------------------------------DEDTGMCALESITNSNPDYY--PYGNLFISEGQPGQVLKVQAKKRIN-MGFLSALQNALYYEYSfNnprQLVGLGGTFVMKNGRAKHHVLPYSWN-ARLKAAADIHNWLHYFVLDAPLIAVGTLVSSS---------------------------------------------------------- ->tr|A0A068XJ06|A0A068XJ06_HYMMI Ester hydrolase C11orf54 protein OS=Hymenolepis microstoma GN=HmN_000316500 PE=4 SV=1 ----------------------------------------------------------------------------------AQASRQVQGMIIGGGLGPFQTYNRPCEVAADITFTSR-GLESNNSLV---GFADKGEELPEF-RSASNSYIATMGQFFVTEAKPGKVIQIEAKGRNGGQNIFDMIQGALYEKYRGeeLPMGVGGVFFLNDSSAQVSLLN-AIPGESYHTYPCVRSYKTPFSINGPIVGAGTIISHDPtslGYMMKSFYCWNTART-LMGQFEYDNNPANAHFQIYLTVATQIYRHDRPV-------- ->tr|A0A0R3SGI5|A0A0R3SGI5_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1 ----------------------------------------------------------------------------------AQASRLVQGMIIGGGLGPFQTYNRPCEVAADITFTTR-GLESNHSLV---GFGDVESESSKF-CRATNSYIASMGQFFVTEAKPGKVIQIEAKDRRGGQNIFDMIQRALYEEYNGeeLPMGVGGVFCLQNSSAKVSLLN-EVPSETYHTFPCVRKYKTSFSIEGPIIGAGTIVSHDPttlGYMMKSFYCWNTART-LMGQFEEDDDPANACFQIYLTVATQIYRHDKPV-------- ->tr|A0A0R3X4K6|A0A0R3X4K6_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1 ----------------------------------------------------------------------------------------------------------LST---EITFSTR-GLQCNRSLI---GFYSKECGSPTS-ERASNTLLSSVGQIFITEAMPGKVIEIVAHKRIGGPSIFDLIQASLYDKFSKqdLPMALGCVFYLQNSGVQASVLC-ELPQEPYHTFPCLKKYQASFTIDGPIIGVGTVLSHDPkkmGFSMSTFNCWNASRL-LTGQFENDVCPEKATYTVYLTPAKKLYRQDKPV-------- ->tr|A0A0R3VSV7|A0A0R3VSV7_TAEAS Uncharacterized protein OS=Taenia asiatica PE=4 SV=1 ---------------------------------------------------------------------------------------------MRAGKE------AINTERSKMQWQR--AEGIIGKSM---ATDHAVCGSPAS-ERASNTLISSMGQLFITEAMPGKVIEIVAHRRIGEPSIFDLIQASLYNKFSKqeLPMALGCVFYLQNSGALANVLC-EIPQEPYHTFPCLKKYQASFNIDGPVIGVGTVLSHDPkkmGFSMASFHCWNASRL-LTGHFENDVCPEKATYTVYLTPAKKLYRQDKPV-------- ->tr|A0A183SVC8|A0A183SVC8_SCHSO Uncharacterized protein OS=Schistocephalus solidus PE=4 SV=1 ----------------------------------------------------------------------------------ANACKVRAGEILGGGTGPYPT-----------------------------------------------------------TGHPCEVIEVIAKRRLCEGSIGKFLHQALQSRYGRgdEPMALGGVFLLEGSGAKYHVLS-ELPNEPYHTFPDLKSYLKCFEMKAPIIGMGTVLSHDPvrlpfififlpsgrvplkegslkqndlGLHMHSFHIYNVERN-VAGHLETDTDPEAASYRIFLHPASHICRMDKPV-------- ->tr|A0A026W8V3|A0A026W8V3_CERBI Ester hydrolase C11orf54 OS=Cerapachys biroi GN=X777_08556 PE=4 SV=1 -------------------THALSMNFSEVAVECIDCPDLRQY--RLVAPGLCGNPAILEIGSLSYLFPQARLDKKYYFKNILRQLNLTsqDNFIIGAGNHSYPPNYDHSElyanFMLS------RASPTDGSMGV-QNASnalwFGGKEFEelKWRYVCEtNPMCAIQGNFFVSQGEPGNIFRINAVNRTGPLDFVSSIQMSLKRMrqkTDPHLIGLGGIFTTSDDNaILHHGIPGKRNATEFYTMNQVQQWLKYKTITEPIIAVGTIMSE----------------------------------------------------------- ->tr|A0A158NTI0|A0A158NTI0_ATTCE Uncharacterized protein OS=Atta cephalotes PE=4 SV=1 -----DLYVPEQTELATVLQNELSTDFEEVTVEWVDCPDLTQEPFNLATPGLCGDTALLDXGGISNLFPFPLKDKIYFQNILQKLDRtQSDNLIIEGGLCTKQSnellveLIMNASFSPAANGTM---TVKNKSSFASIEITQKKKYFVLKSLTDTNPYCNIYGNFFVSKGLREQVLKVHAKHRTGR-DFIVALQHAI--------------------------------------------------------------------------------------------------------------------------- ->tr|A0A0D6LKB6|A0A0D6LKB6_9BILA Uncharacterized protein OS=Ancylostoma ceylanicum GN=ANCCEY_08542 PE=4 SV=1 --------KPSNHELRSVIEAALWKNFKNVQVEVEKCPDLTAAPFHMTSPGFGRNLVIAEVGGWGNLFPNLHKEKLYDI-------KLD------HYTSPYKTLFVNSTK------------------F------------------------VLMGNLAiTPEPGPAEVVHIKCSQRTGKDSFPGCIRKHMAQHYGQ--------------------------------------------------------------------------------------------------------------------- ->tr|A0A026VSB4|A0A026VSB4_OOCBI Ester hydrolase C11orf54-like protein (Fragment) OS=Ooceraea biroi GN=X777_00054 PE=4 SV=1 -----KLHLPDPNRVIDILDHGLRLNFEEVTVDWMDCPDLRK--FGLAAPGLCGNPVLLELGNLSYLSPWPRQNKIYSFKHILSQLDLLGqdNFIIGAGK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ->tr|A0A026W8V3|A0A026W8V3_CERBI Ester hydrolase C11orf54 OS=Cerapachys biroi GN=X777_08556 PE=4 SV=1 ----IDLHVPDPTTITNVLTHALSMNFSEVAVECIDCPDLRQY--RLVAPGLCGNPAILEIGSLSYLFPQPRLDKKYYFKNILRQLNLTsqDNFIIGAGNHSY---------------------PPN--Y-D---------------------HSELYANFMFSPTRPAGSMDVQNKRITVWstMENNNCMHEVCKINPLCAIQGLGGIFATFHESNLYHIMPAFSKATDLYTMNQIQQWLKYS-------------------------------------------------------------------------- ->tr|A0A1I7T578|A0A1I7T578_9PELO Uncharacterized protein OS=Caenorhabditis tropicalis PE=4 SV=1 ------------QETFQVFQTALDNNFEAVQVDIVECPDLSKPPFNQKSSGFGQNLKIAEVGGPGNLYPGFHIDHQFDISTIGKVCEHPEASIFGPGAGPWPVVGQNCEMVAD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A151XCV3|A0A151XCV3_9HYME Uncharacterized protein OS=Trachymyrmex zeteki GN=ALC60_02839 PE=4 SV=1 ---EIPLLTPTISEIAEVLHNEMQPLFHEVNVDIASCPCLTVAPYNLAGVGLCGNTSVIMYYPE-NSEGW--NHRTKNIRDMLT-ASCRDSFVIGATYAT-------KPSMP---------------YYGHLIMN---------------------ATYRAPNGI-------RN---ESRIISA------------NK--ALGGVLRIKNGRVACNVMWDDY----------EEPMPRFYDFIqqqqCPeidvesdMVAVGTMLSEKPELltnqeqryGLNLykrSEFHCFSNIETGGQFISDTTPDTTEYEGYFNVAEQI--------------- ->tr|A0A151J8Z9|A0A151J8Z9_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex cornetzi GN=ALC57_06156 PE=4 SV=1 ---IYPMMPPNILEIADVLQNGMQPLFHDVRVDIASCPDLTTAPYNLAGVGLGGNTSLVEFLRHDVHTPW--KHRTRDILKVFT-GSIRDSFIIGSTFAT-------KPTMP---------------YYGHLIMN---------------------AMYTAPMGI-------RN---ESRLIFA------------ELRngqtriekltdpnqmiytckgnffisegregpvirvrakgrkksdtdiitsmqtvlyehygrnwktVALGGVLKMTNGRVACNLMWDEY----------QEPILSFPDFVraqqCTeiclesdMVAVGTIFNRQPLLfnqeqryDLNLynrSEFHCFNNYGAGGQFISDTTPDTTEYEGYFNVAENI--------------- ->tr|A0A151JUE1|A0A151JUE1_9HYME Uncharacterized protein OS=Trachymyrmex septentrionalis GN=ALC56_09563 PE=4 SV=1 ---TFPTNPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTTIIEFLHINDNVPW--NHKTRDIREILT-SSCRDSFIIGSSYAS-------KPHMP---------------RYGHLIMN---------------------ATYRAPMDL-------KN---ESRLIFA------------ERRneqttiekltdpnkmiatqgnmfvsEALGGVLKMKYGSVACNLMWDDY----------QEPLLPFYEFIrrqqCTeihlesdMVAVGTIVNTEPRLwaqeqryNVNLynrFAFHCFSDDGVGGQFVSDTTPDTTEYEGYFNVAENI--------------- ->tr|A0A195EDN7|A0A195EDN7_9HYME Uncharacterized protein OS=Trachymyrmex cornetzi GN=ALC57_04705 PE=4 SV=1 ---IHPLTPLNLSEIAEVLQNGMQSLFHDVRVDITRCPYLTTAPYNLAGVGLCGNTAVVEFLRHDQNVPW--NRRTKDIQQLLT-CSIRDSFIIGSTYAT-------KPNMP---------------YYGHLIMN---------------------ATYKAPMGI-------RN---ESRLIFA------------ELRngqtriekltepnqmiytnkgiffvsEALGGVLKMTNGSVACNLMWDEY----------QEPISPFPDFVreqqCPeiclesdMVAVGTILNNEPKLteeqryGIVSylsQL--CGD-------------------------------------------- ->tr|A0A151JUC6|A0A151JUC6_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex septentrionalis GN=ALC56_09908 PE=4 SV=1 ---TFPTNPPTLSEIAEVLQNGMQPLFQQLTVDIANCPCLTKPPYNLAGVGLGGNTSIIDFVHYSEILPW--YRRRVNIQEILT-SSCPDSFVIGSSYAT-------KPHMP---------------HYGHLIMN---------------------ATYRAPMDL-------KN---ESRLIFA------------ERRngqttiekltdpnqmkatqgimfvsEALGGVLKMKYGSVACNLMWDDY----------QEPLLPFYEFIkrqqCPeihlesdMVAVGTIINNEPGLwtqeqryNIVSylsRLCGQ---------------------------------------------- ->tr|A0A0N5AJK7|A0A0N5AJK7_9BILA Uncharacterized protein OS=Syphacia muris PE=4 SV=1 ------TLVPPLNDFGKAIQEYMKKNFSGVFVEVVpECPDIG---------------------GNAHLCPVPRPDIYYKL-------EFSKGFMFGPGAGPCYVIGVNSEMVAD---ASFSEAPENVAI----------------------------KVGFTS-----------GKKEVGCKMMIT-----------DKPeFCILGNLAIRKIRAF-----GRLSN--------VALTEQYFELDSPVVCTTVIHIRDVnQCNLRLDYTHCYTDSNAG-QFYGDTEPERMEYVDYFVIAEAVYRIDK---------- ->tr|A0A1E1W1F6|A0A1E1W1F6_PECGO Uncharacterized protein (Fragment) OS=Pectinophora gossypiella GN=g.16499 PE=4 SV=1 ---EKPLHVPPLQEIADVLSGGLPATFESVSAAVVECPDLTQPPYNLTSPGLSGDAKLVEIGGPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A183PEH6|A0A183PEH6_9TREM Uncharacterized protein OS=Schistosoma mattheei PE=4 SV=1 --------------------------------------------------WLSGKTIICDVGSFDYLLPVPKKDrvcivlsdllaKHYDLLDVFRNAGVAAGAVIGAGAGPFFLTGSNSEMV--INISSESGVVKNGSLFGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|W2TK28|W2TK28_NECAM Uncharacterized protein OS=Necator americanus GN=NECAME_17819 PE=4 SV=1 --------------------------------STENIPDLTAAPFHMTSNGFGREFSVAAVGSLDNLYPCPNREKMYDLKDVCKKCEAPNAFVFGAGGCPPKVAGKNGELVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|S4PZU3|S4PZU3_9NEOP Ester hydrolase-like protein (Fragment) OS=Pararge aegeria PE=4 SV=1 ------LYTPPLEEIVDVLSRRLPATFEHVEVSAEDCPDLTQQPFNLSAPGLAGDAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A151JTQ9|A0A151JTQ9_9HYME Ester hydrolase C11orf54 like protein (Fragment) OS=Trachymyrmex septentrionalis GN=ALC56_11238 PE=4 SV=1 ----------------QLLQNGMQPLFQQVTVDIASCPCLTKPPYNLAGVGLCGNTTIIDLVYRSEIIPW-NRRKV-DIRKILRSS-CRDSFVIGSSYATkprmphYGHLIMNATYRAPMD-------IKNESRLIFAERRNGQTTIEKLTDPN--QMKATQGIMFVSEGRAGLVIRVRAKGRkTINTDIITSMQTILFERYRrNENKDIGGVLKMKYGSVACNLMWDDYQ------------------------------------------------------------------------------------------- ->tr|A0A1I8J519|A0A1I8J519_9PLAT Uncharacterized protein OS=Macrostomum lignano PE=3 SV=1 ----FRLHRPDLAAVADCLDRACRDAFEDASVELIDsCPDLSEPPFCLAGRGICGGGG-------ENSGP-VEQ-RRYDLRNLLKATGHLDGLIIGAGAASSTRFGRNAELVAN------LGPLGNGCRVASLR-ADGEDNGTENLANCrlsrPDFAEAgLMVDSLCSSGQtDGPVLRLRASRW----------------------------------------------------------------------------------------------------------------------------------------- ->tr|F4X816|F4X816_ACREC Ester hydrolase C11orf54-like protein (Fragment) OS=Acromyrmex echinatior GN=G5I_14552 PE=4 SV=1 --RVYPLEIPTLLEIAEVLQNGMQPLFQRVNVDIASCPNLSTAPYNLAGVGLGGYTSIVELFLLEPNVPWNQR--TRDFQEIFTTS-CRDAFVIGTSYATKPSMPYYGHLIMNATYRAP-MDIRNESRLIFAERGNGQTRIEKLTD-PNQMKYTNKGIFFVSEGRGGHVIRVRAKGRKT---INTDIITVLYEKYENDNKFVGGVLKMTNGSVACNLMWDDY-EEPLGSFDDIIRRQQCaeIHLESDMIAIGTIINDKPVL------------------------------------------------------- ->tr|A0A151JZ30|A0A151JZ30_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex septentrionalis GN=ALC56_03953 PE=4 SV=1 ---TIPANPPTLSEIAEVLQNGMQPLFQQLNVDIASCPRLTTAPYNLAGVGLGGNTSIIEYLHRNDNAPW--NHITWDIREILTTS-CRDSFVIGSSYAAKPHMPHYGHLIMNATYRapmdlkNESrlifterrngqttiekltdpnqmiaiqgnmfvsegragrvirvrakgrkfintdiitsmqmilyeryrrcenkyvesdmvavgtivnteprlwaqeqrynVLimnatyrapmdLKNESRLIFAERRNGQTTIEKLTD--PNQMKATQGIMFVSEGRAGLVIRVRAKGRKTiNTDIITSMQTILYERYKRnENKVVDGVLKMKYGSVACNLMWDDYQ-EPV---------LPFYEFikrqqcpeiylESDMVAVGTIINYEPKL------------------------------------------------------- ->tr|F4X033|F4X033_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_11615 PE=4 SV=1 ---VYPLVPLTLLEVVEVLQNGMQPLFHDVKVDIARCPYLTTAPYNLAGIGLGGNTSVVEFVH--DGIPW--NYKTRNIQDVLTTS-CRNSFIIGSTYATKPHMPYYGHLIMNATYRapmdirNESrlifaerrngqtriekltdpnqmiytnkgsffvsealggvlkitngivacnlmwddyeepmlesfhdfirrqqcpeihlqsdmiavgtiindklkfitaerrydILimnatyrapidIKNESRLIFIERRNRQTKIEKLTD--PNQMIYtNKGSFFVSEGREGLVIRVCAKGRKTiNTDIITSMQMVLYEKYCRnEDKVFGGILKMTNGSVACNLLWDHYE-EPI---------LEsFHDFirrqqcpeiylESDMIAVGTIINDKPQL------------------------------------------------------- ->tr|A0A195CWL7|A0A195CWL7_9HYME Uncharacterized protein OS=Cyphomyrmex costatus GN=ALC62_04540 PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTYGQVACNVMYDEYPEMlPFYDFFL-QQQCSEINLESDMIAVGVIFNSFPVrmteqprygVSIyNRNEFHCFSDFGAGGQFINDISPDTTEYEGYFNVAEKLIIP------------ ->tr|A0A151WZ88|A0A151WZ88_9HYME Ester hydrolase C11orf54 like protein OS=Trachymyrmex zeteki GN=ALC60_07638 PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNGRVACNVMWDEYEEPmPlFDDFVK-QLQCPEIDLESDMVAVGTILNEKPQlltdqeqrygLNLyNRSEFHCFSNYEAGGQFISDTTPDTTEYEGYFNVAEQMNLI------------ ->tr|A0A195CV39|A0A195CV39_9HYME Uncharacterized protein OS=Cyphomyrmex costatus GN=ALC62_04539 PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRYGQVACNVMCDEYPGRiLsFNNFFL-QQQCIEITLESDLIAVGVIFNNIPLpladqeqrygINLyNRSEFHCFSNYGAGGQFISDTTPNTTEYEGYFNVAKKLIDV------------ ->tr|A0A151WZT1|A0A151WZT1_9HYME Uncharacterized protein OS=Trachymyrmex zeteki GN=ALC60_07639 PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGGVLRMRNGRVACNVMWDEY-EEPMPPFYDFVKQLQCPeiDLESDMVAVGTILNDKPEllpqeqrygLNLyKRSEFHCFSNSEAGGQFISDTTPDTTEYEGYFNIAKKLN-------------- ->tr|A0A195ET10|A0A195ET10_9HYME Uncharacterized protein (Fragment) OS=Trachymyrmex septentrionalis GN=ALC56_14249 PE=4 SV=1 -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LFVSEGGVLKMKYGSVACNLMWDDYQEPmlPFDDFIRGQQCS-EIYLESDMIAVGAIMNDKPELLtqeqrygtnvYNRSEFHCFSNYGAGGQFINDTTPDMTEYEGYFNVAEKY--------------- ->tr|A0A183X9N9|A0A183X9N9_TRIRE Uncharacterized protein OS=Trichobilharzia regenti PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLVIWLKLIVLTSLIIFcfilinlFSVLSSTQHRLGLRLEHFHCFNQdQTNCGHCHFDTHGPTVAYRAYFSLAEKLIRIDQPNK------- ->tr|A0A195CVI4|A0A195CVI4_9HYME Pro-resilin OS=Cyphomyrmex costatus GN=ALC62_04538 PE=4 SV=1 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEGGVLRMRYGQVACNVMWDEYPNGMLQ----FGNFyfeQRCIEmtLESDLIAVGVIVNNAPypfsaqryGINLYnKCEFHCFSNYGSGGQFISDTTPDTTEYEGYFNVVENLIHVPNVN-------- ->tr|A0A151JPR3|A0A151JPR3_9HYME Uncharacterized protein OS=Trachymyrmex cornetzi GN=ALC57_01503 PE=4 SV=1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FISEGGVLKMTNGRVGCNLIWDEYRDRIL-PFPDFVKAQQCteICLESDMVAVGTIINHQPLqfnqeqrygVNLYdRSEFHCFNNYGAGGQFITDTTPDTTEYEGYFNVAENS--------------- ->tr|F4WZJ6|F4WZJ6_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_11421 PE=4 SV=1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVSEGGVLKMTNGIVACNLMWDDYEEPMLESFHDFIRRQQCpeIHLQSDMIAVGTIINDKLKfitaerrydVDLYeyRSEFQCFSNYEAGGQFISDTTPDITEYEGYFNIAKNM--------------- ->tr|F4W740|F4W740_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_01248 PE=4 SV=1 --RVYPLASPTLLEIAEVLQNGMQSLFQRLNVDIASCPHLSTAPYNLIGVGLCGNTSIVELYPFQENVPWSQRT--RDFREIFTTSCC-DSFVIGTSYAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A026VU98|A0A026VU98_CERBI Uncharacterized protein OS=Cerapachys biroi GN=X777_00165 PE=4 SV=1 -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FRVVNIPTLHHIMP-AFgSKTNLCTTTRGYKWLTYSKVVEPLTAVGTIMSEGGYynnicsnyeynTYITKSHFHSYNRsTEEGGHYYGDYDPTFVssnsfgSYIGYFSFADKLYVMDPPDRTHNI--- ->tr|A0A0C2CLF8|A0A0C2CLF8_9BILA Uncharacterized protein (Fragment) OS=Ancylostoma duodenale GN=ANCDUO_19282 PE=4 SV=1 ---------------------------------------LTAAPFRMTSNGFGRNLVIAE--------------------EICEKCGAPKAFVFGPGACPSRVVGA-GELVADANLSEN---IVT-SKVTTLVK---DHILKYKTKMINSTKFSLMGNLVVSEL-PGP-SEVDMTSRLDQVDFV---------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A151JT76|A0A151JT76_9HYME Uncharacterized protein OS=Trachymyrmex septentrionalis GN=ALC56_13780 PE=4 SV=1 -----PKNPPALSEIAEVLQNGMQPLFQQVTVDIASCPCLTKPPYNLAGVGLGGNTSIIEFLRHNEDAPWNHIT--RDIRVILSSS-CRDSFIIGSSYASKP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A026W8I3|A0A026W8I3_CERBI Uncharacterized protein OS=Cerapachys biroi GN=X777_08555 PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDpRMIGLGGIIFLNDNIpTLHHVTPSCYSLSNLHTMNQVQEWLQYKTTLEPVTAIGTIMSEGGYyknLcpsstenpYITKSHFHSRMPSGSGGHLYTDFVdnnYSDAYYVGFFSFAEKLYCVDPPSHQD----- ->tr|A0A183B0J5|A0A183B0J5_9TREM Uncharacterized protein OS=Echinostoma caproni PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSLFSQNQQWKLRLEHFHCFNRdRTKAGHCHFDTDGTAASYRAYLVPGRKLLRVDKPQ-------- ->tr|F4WYH8|F4WYH8_ACREC Putative uncharacterized protein OS=Acromyrmex echinatior GN=G5I_11031 PE=4 SV=1 ---------------------------------------------------------------------------------------------------------------------------RNESRLIFAERGNGQTRIEKLTD-PNQMKFTNNGIFFVSEGRTGLVIRVRAKGRKTiNTDIITSMQTVLYEKYKRnEDKVVGGVLKMTNGSVACNLMWDDY-EEPLESFGDIIRSQQCaeIHLESDMIAVGIITNDMPQL------------------------------------------------------- ->tr|A0A183QJR6|A0A183QJR6_9TREM Uncharacterized protein OS=Schistosoma rodhaini PE=4 SV=1 ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QEHFHCFNQdQTNCGHCHFDTHGPTVSYRGYFAIAEHLLRIDQPSK------- ->tr|A0A151WZ90|A0A151WZ90_9HYME Uncharacterized protein OS=Trachymyrmex zeteki GN=ALC60_07640 PE=4 SV=1 ---RIPLSAPIISEIAEVLQNGMQPLFHEVNVDVASCPCLTGAPYNLAGVGLCGNTSVMKYRRFitENLEE--RNHTTRNIRDILTTSC-HDSFIIGSTYA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A151JY44|A0A151JY44_9HYME Sterol O-acyltransferase 1 OS=Trachymyrmex septentrionalis GN=ALC56_04665 PE=4 SV=1 --RQYSLNEPTLSKIAEVLQNGMQPLFQQLNV-IASCPCLTTAPYNLAGVGLGGNTSIIEFLYLNDNVPWNRR--TRDIREILTTS-CNDSFVIGSSYATKPHI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ ->tr|A0A0C2GEL8|A0A0C2GEL8_9BILA Uncharacterized protein OS=Ancylostoma duodenale GN=ANCDUO_14299 PE=4 SV=1 -----------------------------------------------------------------------------RAQEVCNTCGAPKAFVFGPGGCPPSAVGVNGELVADANLSENK--VA--SKVT-IQL-D-NYTTPYKTLLVNSTKFVLMGNLAITPePGPAEV------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A0C2G9J1|A0A0C2G9J1_9BILA Uncharacterized protein OS=Ancylostoma duodenale GN=ANCDUO_14297 PE=4 SV=1 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETFGPALRTMLLKRSVAfSCVSLAGIFLLLRGKADVHIAP-DFPDKPFKSMEE---------------------------------------------------------------------------------- ->tr|A0A183RET9|A0A183RET9_9TREM Uncharacterized protein OS=Schistosoma rodhaini PE=4 SV=1 -------------------------------------------------------------------------------------------------------------------ISSENGVVKNGSLFGSYDKENNKPLLT----KADNTKFALLGQMFMCEGKPGPVSEMN--------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A026W9R7|A0A026W9R7_CERBI Uncharacterized protein OS=Cerapachys biroi GN=X777_08554 PE=4 SV=1 -----------------------------------------------------------------------------------------DNFIIGAGKHSAPPYYNHGQLFANLMFSRA--NPTNRSI-GLTNKNTASWSFmENitYMQNTweDNPTCSTQGNFFLSEGKPGKVLRVVF-------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A151JY71|A0A151JY71_9HYME Uncharacterized protein OS=Trachymyrmex septentrionalis GN=ALC56_04664 PE=4 SV=1 -----HLTSSTFAEIAEnmFLQNGMQSLFHDVKVDIARCPYLTTAPYNLSG--------------VEN---W--NHRTCNIQDVITIS-CHDFFIIGS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- ->tr|A0A183CMN1|A0A183CMN1_GLOPA Uncharacterized protein OS=Globodera pallida PE=4 SV=1 -----ELIKPNVAELIPELRSVLRPAFSSVHCDLATCPSLNQAPFNLPVQGPGPNFTF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- diff --git a/esm/examples/hhblits_uniclust_2017_10_5ahw_1_A.a3m b/esm/examples/hhblits_uniclust_2017_10_5ahw_1_A.a3m deleted file mode 100644 index ae44844..0000000 --- a/esm/examples/hhblits_uniclust_2017_10_5ahw_1_A.a3m +++ /dev/null @@ -1,3262 +0,0 @@ ->5ahw_1_A -SAYQTVVVGTDGSDSSLRAVDRAGQIAAASNAKLIIATAYFPAPIYAILREANDRAKAAGATDIEERPVVGAPVDALVELADEVKADLLVVGNVGLSTIAGRLLGSVPANVARRSKTDVLIVHTS ->tr|A0A191HSK0|A0A191HSK0_9FIRM Uncharacterized protein OS=endosymbiont 'TC1' of Trimyema compressum GN=AZF37_00820 PE=4 SV=1 ---YKNIVVGVDTSPQAYEVFKKAMDVAKTEGSTLHIVSAVPFIPDTdvinttielgvtpsvrqeqefaveikerrAILETYVA-eAKEYGV-eTVTLTIESDHSKNLILTELEDFEGALIVIGASTKTPLKRFMIGSTAKYLATHAPCNILIVKSY ->tr|A0A1G0MC00|A0A1G0MC00_9DELT Universal stress protein OS=Geobacteraceae bacterium GWC2_55_20 GN=A2X82_10850 PE=4 SV=1 ---RKKILVAIDGSPQSDKAAEEAVRLAAGNQSQFKSPVFALLVLPNaptstytdfvpsapmtetekwddlrrrifFVVEKCAA---EHNIPl-EMIVE-YGDPAEKMISFAKREGIDVIVIGSSSKGFIQRRIKGSISHKIASSAPCSVYIVRG- ->tr|A0A1Y4FWL9|A0A1Y4FWL9_9ACTN Uncharacterized protein OS=Gordonibacter sp. An230 GN=B5F40_12895 PE=4 SV=1 --GGRRVFAALDETPAREAVARAALELAEDSGGHLLFGHIADALsreaamtdlealrrsaeerlehHLADVLKAARGSRRLAS---FELIVEAGPAAQTVvRSLMLPFEPDLVVCGRCREARLHCRIATGVGAALLRAAPCSVLIVE-- ->tr|A0A0X9VCG1|A0A0X9VCG1_9BACL Universal stress family protein OS=Kurthia sp. 11kri321 GN=ASO14_1320 PE=3 SV=1 ---TKKVVVAYNDTDLSNDVLDYVHEILEMHaEIELNIVYAYEHPLE-npspfqrnyddgapemlayaeQIIQKAKNRF---VDlpNHVEGFVYDTGPAAAILSHAHDHHADLIVIGNRGTRGLREL-VSSVSRTIQTKSHIPVLTF--- ->tr|A0A0C5BVJ8|A0A0C5BVJ8_9ARCH Universal stress family protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1069 PE=4 SV=1 ---TKRIMVCLDGSKNSLRGLDKAISFAKQSDTIIVGVH--SDtsfsafsavrapilP-mkkwkqkAKALMNIAKKKVEKNKIEFEGIVIAGHTSGIDLTtfANNPANKIDQIVIGSRGMGFPKELFFGSTSNFVLHKAKAPVTIVK-- ->tr|A0A0F2Q180|A0A0F2Q180_9CLOT Uncharacterized protein OS=Clostridiaceae bacterium BRH_c20a GN=VR72_21865 PE=3 SV=1 ---FKKILFPTSGSPVSEKIALTIVNLISDTKN-AEITIVYVLQVTpfhrtvsYqledkgidsskLaledikdILEKATKVFRENNI-PYTi-rV-ELGEPVEMILKIAEe-TKSDLMVVGFHGHSTLSDYLFKGNITNeLIDKTNCPILVVK-- ->tr|A0A0P7XFL6|A0A0P7XFL6_9BACT UspA family universal stress protein OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_06575 PE=4 SV=1 --LPQNWLIATDGSKYATMSVEYAARLYaCMSpRPNVLLLNIIPdpRRKgavdheteagSRRVLAESRQFFLDlagSDE-TVSTMVGIGEPRQIIVETVKANKIDHLIMGGADYqWRITDLLSGGVTNYIIEHVSCVITLIK-- ->tr|A0A127QJP0|A0A127QJP0_9BURK Universal stress family protein OS=Collimonas arenae GN=CAter282_2255 PE=3 SV=1 --MLKRILVAIDGSELGNNALRHGCALAKEQGCEIRALYINvdpflafpllgvvyFQrEQMLQAaaeqaagvRAVAL-kVFDAFELRgdvQILDLQEKGkRVADLIREVSSRWNASVVVMGSHGLQGMQRLMLGSVAEHFLRIADCPVLIMKS- ->tr|R8DTA9|R8DTA9_BACCE Uncharacterized protein OS=Bacillus cereus VD133 GN=IIU_05957 PE=3 SV=1 ----MNIVVPMDLSSHAQLALKEATQLFKGANFII--LIVVdiidepenvfDwQGNMY--ESkihlfkEINAFIE--RqkemfP-NAsIEFdVCSGEAKHEIIHYARQhNEIDCVVIGATSKRALSKVILGSTTDYVVKHINHNILVVR-- ->tr|A0A1E8D0Z5|A0A1E8D0Z5_9MICO Uncharacterized protein OS=Humibacillus sp. DSM 29435 GN=BA895_00715 PE=3 SV=1 ---KNCVIVAVDDSSASRAAHRWAASYARATATDLCAVHVLDWPIGLVGHpgeprtrlyvparhvapsyRRRLHRVLDdsdstvDeatgpaadsetdiDScAASSLHFAQGPVGEVLVRLS--THATLLVIGTREPLrDGHRLVTGSASHYCVSHATCPVVTVPE- ->tr|A0A1F2QI41|A0A1F2QI41_9BACT Uncharacterized protein OS=Acidobacteria bacterium RIFCSPHIGHO2_01_FULL_67_28 GN=A2620_02860 PE=4 SV=1 --APKKILVSLKQASDAGELINLA-RHVAAPGARITALHVVEVPAATPlgaedraldapaeAVERAVKKlark--HRGVKIAVRLLRARHAGKAIADELKEGKFDLAVMSYHHKRSLAELLLGTTASYLAKHAPCRLLMSVP- ->tr|D3BL96|D3BL96_POLPA Uncharacterized protein OS=Polysphondylium pallidum GN=PPL_09328 PE=4 SV=1 ----MKYLIAIDGSDHAHNAFMKAVALYKPGDEI-YTLIaidlVHFMMAApklaeetttladmKekmlangnKLSGQYAELADEHNIAKYKTLLLEGNPRELIVKeVA-ERKIDILIIGQVGLINNPNISMGSTSTYCIRNCQCDVLLFWS- ->tr|M5J4E9|M5J4E9_9LACO Universal stress protein OS=Lactobacillus saerimneri 30a GN=D271_07799 PE=3 SV=1 -ERYQNILVEIDGSKQSYEAFRRALEIAQRDQAKVYAVIiinnslSLLRTVAinvaydin-iqtnaqSNLDRCRVIAHNTGFQDLHTMILEGRSKATMLRdFIADHDIDLFLAGSKRKQFLDLLFTDSIATKVANFTNCDVSIVK-- ->tr|A0A1H6IYN5|A0A1H6IYN5_9MYCO Universal stress protein family protein OS=Mycobacterium rutilum GN=SAMN04489835_1231 PE=4 SV=1 ----RLGVVVGIGTGVSTTATQWATHHAATHRIPLTLVTTGTTASQtiktgwdslpl------------------VRAIAVDAPLEHTLIQLSAQ--AEIVALGNDCPSTH------RTLSALVRRGHSNVASIPE- ->tr|A0A1G9JQQ8|A0A1G9JQQ8_9GAMM Nucleotide-binding universal stress protein, UspA family OS=Dyella jiangningensis GN=SAMN04487785_11934 PE=3 SV=1 ---FKRILLPIDGSEQSLRAASTGIALAAQGEHQAFGLEVLCPTPSItlvadAIvhdssnhtdrairkahddLAEVAGMARDAEVAFADIYVFDQRPYTAIIAAAHSAGCDLIVIGAGEYARGRGAQLSREVSLLVNSAEMPVLVCP-- ->tr|D6SKL4|D6SKL4_9DELT UspA domain protein OS=Desulfonatronospira thiodismutans ASO3-1 GN=Dthio_PD2634 PE=4 SV=1 -----NLLVPHDGSEFANKTMDKAIDFCRKLGGGkVYSVVvvpdLciSFVgrdecNLLestlqkegNEIKNNVQGRLTEKG-VDGQVMIKSGAPEKVILETADEVDADYIVMGASGSHGAdARGVLGGVTCKVINTGKRSVIVI--- ->tr|S7ITH0|S7ITH0_9FIRM Universal stress family protein OS=Megasphaera sp. NM10 GN=NM10_10615 PE=3 SV=1 --SYQHILVPIDGSDHSKQALQHAIDIARITGGAITLLSVAnMADIInqfgqmentseLTMDEMtasaqanstglLKKFAAMIPASlSVQSIFELSAPEAAILAEQKSQSADLICMGRGGGQALKNFLLGSAQHLRHHPRTLPGPLGP-- ->tr|A0A0P7ZZC8|A0A0P7ZZC8_9CYAN Universal stress protein family protein OS=Phormidium sp. OSCR GN=HLUCCO16_10015 PE=3 SV=1 --DPYRLLVGLDQTTLADQVFQQALTLAQDRQGELYLVHCLNLEFqgqlgtlldvgMglqsrinldelqqsqqvkqlkaaRRWLRQLCEQAAQRQV-PCDYRLDRRSPGPLLCYLAQDWSADLVVVGNGKKEVWQALILGSVSKYVIEHSPCPTLVIPG- ->tr|A0A1V4RF00|A0A1V4RF00_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. 4484_143 GN=B1H06_00300 PE=3 SV=1 ----KSLVVAIEFPIKRRELVDIAKKMAVEFKAKLHIVHSesvdsyiqhivvednlqLTDEIMQQykenfkkQLNDLQDELSADKI-EAECILIEGPSVDGILKIAKEVKAEMIIIGSHEHGKFYHLIFGSTHNLLIKKSTIPILIIP-- ->tr|A0A1G0CQW6|A0A1G0CQW6_9PROT Uncharacterized protein OS=Gallionellales bacterium GWA2_60_18 GN=A2Z95_05360 PE=4 SV=1 ---QHEILASVGDTPLAQEIAKLAGGIAAACDLPLTIVGIAERQDArsraESLNTLYVALASALAKR-VQGRVCDGDPAAQTNAVAREISADLVIIGRQRYHLLP-FMHgkTSIMQKIIGANEVPTLVVP-- ->tr|A0A1H0SY73|A0A1H0SY73_9ACTN Universal stress protein family protein OS=Nakamurella panacisegetis GN=SAMN04515671_4338 PE=4 SV=1 ---ARTVAVGATSSPGGRAALKFASHEAIRMTASL--VAVIGADRHseqaRAILQNLEHvENECPGLP-IEIHWEKGDVAPALIRIS--QTSQIVVLGTHHSPDRWSIRLGPVTDLVLGHTACPVITVA-- ->tr|V4YM98|V4YM98_9ARCH Universal stress protein UspA related nucleotide-binding protein OS=uncultured archaeon A07HR60 GN=A07HR60_00401 PE=4 SV=1 --MYDEILVPYDGSDEAMKGADDAIQLAAAVGASIRALYVinisgtpRSVYISqdDDElkedFRSYgrevATDLcDRASEEGVDCstVIRSGDVATEIVDYADAEEMDLIMMGSGYKGA-IGSLLGGKASKVVRNATVPVTTCRVT ->tr|D4YMY3|D4YMY3_9MICO Universal stress family protein OS=Brevibacterium mcbrellneri ATCC 49030 GN=HMPREF0183_1240 PE=3 SV=1 ----DSVVVGIDDSESAREAAHFAVAHFADArEIVLVAVIPdGTRpVLPApgdvttPytgslpavqpaipseedrkkceaMLDDLRTQlesThkdsETTSA-PIKTRVMAGDPAEQLATLGD--DAGLLVIGHHGADQKFAGRIGRTSRGLPGHSLCPVLIYR-- ->tr|A0A1C4ZUP3|A0A1C4ZUP3_9ACTN Nucleotide-binding universal stress protein, UspA family OS=Micromonospora purpureochromogenes GN=GA0074696_4920 PE=3 SV=1 ----APVVAGISVLPQAMEVVREATRAAAAHRRNLVLLHAFNWQAafeatsvaeprAeaEEMIARAAATAAEIEpAVSVSGEIVEGPPLDALIRRSES--AFLVAVGDGGMTTCGDCVPPDaPAVQLAARAGCPVLVVRR- ->tr|A0A0K1ECK5|A0A0K1ECK5_CHOCO Universal stress protein OS=Chondromyces crocatus GN=CMC5_027430 PE=3 SV=1 --SYRKPALALELDQAACDVITLLLQTLPSPCPPVAVVHAYNA-PYQNLIYpslseeegagyrnQCrqqaiqgvAKLLaaavdqvDDPEatEVPWKTYIRHGSPRDVIPKVVETANIDLLVLGTRGYAGIAHAFLGTVAGEVLREVGCDVLVVPP- ->tr|A0A0D2WBF3|A0A0D2WBF3_9PROT Uncharacterized protein OS=Skermanella aerolata KACC 11604 GN=N826_05990 PE=3 SV=1 --LYRRVLFAIDATNPSARAAYAARNLPFLEAADISVLHAFWAP-GKGKLRqagvnpariaqyveetalEAATDlvsfLHQEGRHdpIEKIVFTEGEPVSAIREAAARWRSQLAVIGIQRRTGLRRLLCPSSAKQILRQVTCDILAVPL- ->tr|A0A1I3P7Q1|A0A1I3P7Q1_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Celeribacter halophilus GN=SAMN04488138_102224 PE=3 SV=1 --PYKSVLCGIDLSPSCLAAGKAALEI--VPEAKFATFHAVHIP-YRGMLApeasekqlapfvkDANAEldkwWESSAIPkgLPKPTVTPSSVQDAFQGAMEESEADLFALGAHGRMPLSPTLLGGFTEYQIRNPRTDLLIVRD- ->tr|A0A1V5WZC7|A0A1V5WZC7_9DELT Universal stress protein family protein OS=Deltaproteobacteria bacterium ADurb.Bin207 GN=BWY17_04855 PE=3 SV=1 ---MKTIVAAIDFSDTTTIVIDTAVQLAHALHAEIVLFHATPPSGTwlmAGLDGltaaGMLHPVlwerqqqdilqqhldnliTqvQKQGLTVRSHTTSAVQRNAICQALESLHPDFIVIGSHRHGSLYELLGPGICSRIVRRAPCPVVVVHS- ->tr|K2J6P1|K2J6P1_9PROT Universal stress family protein 3 OS=Oceanibaculum indicum P24 GN=P24_00155 PE=3 SV=1 ---IGTILTATDLSPRAGAAVQRALALKREHACALVIAHIIDRPTSSLdverRSRTAFKTIDGQlQelppeeREDIAIKVTTGTPQWELGRLAHMHRSELVVLGRHEPRGGHDLLVGSTAEGLARDGNCSLLVVAD- ->tr|A0A1K2HSG8|A0A1K2HSG8_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Vasilyevaea enhydra GN=SAMN02983003_0158 PE=4 SV=1 ---LRHITLATDLTARSDRATERAIQLAAQFQAKLLVVHAVEAAVSaiwdggpsWRraldLAEMARRRLFGDlPlsqSVDIDVVVERGDPFEVVLRTCTDAGSDLLVTGVAREEIYGSSRAGRMVEQLASRAPAPLLVVKR- ->tr|A3TMN9|A3TMN9_9MICO Universal stress protein family protein OS=Janibacter sp. HTCC2649 GN=JNB_12573 PE=3 SV=1 ----GAIVVGVHNRPSDDNAISQGIRQARLSHRPLHLIHALSpgivpwtaeyie--TKNLALKECRDRAAEKASdLDISCTl-HVDEPAGVLVEASR--SAALVILGSSGHSRSVDVARTAITRKVISHAASPVLVTP-- ->tr|E6QN35|E6QN35_9ZZZZ Uncharacterized protein OS=mine drainage metagenome GN=CARN6_2142 PE=4 SV=1 --PLRHILCAISLHSPAMLVAELATRIAADHGAELTLLHVMPTREEArldpgysa---TTLEARmrsllspPAQRQLR-IESISTTGDTAEEIVYQSNLRQSDLLVFGAHEASTLSTLVRQGVINRVLGQALCPVMTLAD- ->tr|A0A1E4K1H9|A0A1E4K1H9_9PROT Uncharacterized protein OS=Thiobacillus sp. SCN 63-374 GN=ABS92_16150 PE=3 SV=1 ---YRRPLAAVDFSPDSHAALAWAAHLSAD--GSAEALHVLPNEDERhlrgvglsaeav---RQRRVDmraiaknlmanlladM---PAQ-AAGHIEIGPAAKIILERAAERRADSLFWAGKVPAGWR---SGCWAA---------------- ->tr|A0A1Q3TUX5|A0A1Q3TUX5_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_00640 PE=3 SV=1 --GWPRLLLPLDMTDKAEAALNLSLELARRLRASLYLLKVNNPVPHShnlsgdpdalakldlYGKSEANFYleqieklAEEKGVE-VVKIVLVGNPETEIRSFADLFAPDALIMATHAAGTnlAGTSNPPSLTLEIMRRSHIPVFMVPL- ->tr|E3GX85|E3GX85_METFV UspA domain protein OS=Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S) GN=Mfer_1294 PE=4 SV=1 ---FKKIMIATDGSENAEKAAKVGIDLAKSVGGKVIAVYVMDERLMqpydvmedegKNALKRIQKIGRKKNVV-VDEILILGNPIEDLPKIANKVNADIVVLASQSKGKFERIILGSTTKSMLENCNVPLLITP-- ->tr|W6WZR5|W6WZR5_9BURK Nucleotide-binding universal stress protein, UspA family OS=Burkholderia sp. BT03 GN=PMI06_008774 PE=4 SV=1 --VNQAILIYYDGSTEGKRALYRAGEMAFSPGAEIHVLavvdvmsaivsSAGLlSDiacsdivkKTWSVLDEALDHLSAKDIA-ACGHLGYGQVVECIARYANLVDADVIIIGYRLRRGLsT-WWRSNRAhIELLEHAVGRAIMAV-- ->tr|A0A0C2BZ21|A0A0C2BZ21_9BURK Universal stress protein OS=Noviherbaspirillum autotrophicum GN=TSA66_24450 PE=4 SV=1 --MYRKILVAYNGTPESRGALQECIRLEPGPATEIHLLavvtpmpiviaAEFAaavpTIeeeeaeqrTMKQVLESGRLMLADAGLK-VIPHLEVGEPANIIAGMVQKLGIELVIVGHSRHKSFaMRWWRGAMDAVLVEKVHCAVMVAA-- ->tr|N0B4E8|N0B4E8_9RHIZ UspA domain-containing protein OS=Hyphomicrobium denitrificans 1NES1 GN=HYPDE_31043 PE=3 SV=1 ----HKILCAVDGTSHSDKAVQFAAELANRLGSKLTIASVNVMiggarsgamyikedREVQQVLDVAENAATGAGAKNVDTAFLRSREAaAGVVAYAEQEDYDIIVTGTGDKHGLSRLVLGSVAADIAGRAHCTVIVA--- ->tr|A0A136NCC1|A0A136NCC1_9BACT UspA domain-containing protein OS=Bacteroidetes bacterium OLB11 GN=UZ11_BCD004000521 PE=3 SV=1 --FKKFYYAQQIFSAESKEAIRYAVKMGNQSQTVIHLIHTLEAPIvmdsnsamyyqkMIDTLNAsaendmNnLLAELREKYSGYQFTGvvkDNADSAESIVEFAKSIEAEAIIMSSHGRRGIKRLLMGSVTESVMRLSDIPVVIIR-- ->tr|A0A1S2I591|A0A1S2I591_9MICO Uncharacterized protein OS=Curtobacterium sp. MCBA15_013 GN=BIV01_18315 PE=4 SV=1 ---MTAYTVAIDDSVAGWKTVDWAVDAVEPAVDDVRLLTVSEFfgeaLTrSEHRLDAAEQRLRTvHPGLSVTHDVTGGPTADRLVADA--ALGDVLVIGAPQVHTLTAAITGRVAERIVAHATTPVVVVP-- ->tr|W8WT07|W8WT07_CASDE Universal stress protein, UspA family OS=Castellaniella defragrans 65Phen GN=BN940_00861 PE=3 SV=1 ----KDIVLATDGSAYSLQAARYIAQ-SGLLPAGGVVRILhvmaglparvshFVDaAAIQDWYNEESAKVLeptaeilRQAGVPHETESRVGFAPQEITRYADEVDAHMIVMGAHGRGVLLDAVIGSVAGRVLALTQRPVLLIQH- ->tr|A0A0B7A582|A0A0B7A582_9EUPU Uncharacterized protein (Fragment) OS=Arion vulgaris GN=ORF94165 PE=4 SV=1 -----PRIERYGGVACRPYVTCKGFSKHVYKLGDEVVLVYVPEGHGllsaskwenavytlsrdvMmAASEEEEQKIKTDL-erfavklhelglEGKVRNVMASKPEEGILRACEEENAEMVVVGSRGKGTLRRTFLGSVSDYLVRHATCPVVVCKR- ->tr|A0A1Y2CNP5|A0A1Y2CNP5_9FUNG Adenine nucleotide alpha hydrolases-like protein OS=Rhizoclosmatium globosum GN=BCR33DRAFT_657677 PE=4 SV=1 ---TRVICVALDESKYAEAAFNWCLKHLCRNSAesnglidEIVLLHVRQLPLKlstslgddmipdatvysneeyVnWANQQSLVGSQELLKkygnrlmdlnkgVVIRCVSLTGDPRAELVDAAKNLKAEMMVVGTRGMGLIRKAMIGSVSDHLLHHLECPVIVVRA- ->tr|A0A0L0FI71|A0A0L0FI71_9EUKA Uncharacterized protein OS=Sphaeroforma arctica JP610 GN=SARC_11021 PE=4 SV=1 --APRTIVVAVNNSEGGVYAVEWAFKDFVRPTDNVILVNvvdt-ythYiPNFgtTVTfdMATNHVQKEvvenaqtllaylakqMsMrPGQI----eTKVIAGDARDVMVELTEEQDIDVVILGTSNKTLLRRKLVGSVGSYLVEHCKCSVIIAK-- ->tr|A0A0F8XZU9|A0A0F8XZU9_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_3154580 PE=4 SV=1 --------VPYDDSKYSERAFSLALDLANHYGASITTITIVYENpaTDLDirHQTSFDkdkikkinekfkllqEIATKFGITLKNDIAKRREILDPILTYITENKMDLVVMGSRSRSGPNQFVLGSIALGVCKSAKCPVMLV--- ->tr|A0A1X1TZ47|A0A1X1TZ47_9MYCO Uncharacterized protein OS=Mycobacterium engbaekii GN=AWC02_06095 PE=4 SV=1 ----GLVLAVVDGSSAGDGVLELGAAEARLRGLPLRVFALPQHRPAapgesdVPSDPPLPTAVDRWlsRCrqehpdLDVDSVGYHEGLLNCferLQRSGS--AIQLAVVAPRRPGPLD-VLLAPAGRAVVESAGSAVLVCDR- ->tr|A0A1W2DDH8|A0A1W2DDH8_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Fulvimarina manganoxydans GN=SAMN06297251_11449 PE=3 SV=1 ----TTLIIGIDGSKAGERALAHGKRLSRLIGdCTLLLVYVIEWSPYKfqsaeenamrhkrreeeieiakmRVIEPLLSALKSEGLD-ADCRVRHGDAAEILNAVALEHRAEQIVVARGSESGFASRVFGTVAIKLVSSASVPVTVV--- ->tr|A0A1Q4E5I8|A0A1Q4E5I8_9SPHN Uncharacterized protein OS=Sphingomonas sp. 67-41 GN=BGP17_16030 PE=3 SV=1 --MFHHIVHANDGSENSLTALRTAIELAAVADTGLDVLFvediaprtGMIADVtAheteeRRHI-GRHKALAERiaarSGVTLKTHVFTGHPVGHIVAFTREAKADLLVIGATEHADLWEHLFGRRSDRMTHKVDCSVLIVR-- ->tr|A0A0E9M5T9|A0A0E9M5T9_9PROT Universal stress proteinc/MT2061 OS=Ferriphaselus amnicola GN=OYT1_00927 PE=3 SV=1 ---FERILLATEHTEFDVGAERVAFALSKHCGLPLDGVFPMRSNPEYEIEapqlvvkaeREAAAKIAqicaAAESqgVELNVSARRGeMRYREVVEEATRLHSDIIVVRRRGKRGfLAQLMIGEMVSKIVGHAPCSVLTVP-- ->tr|A0A075WVZ0|A0A075WVZ0_9BACT Uncharacterized protein OS=Thermodesulfobacterium commune DSM 2178 GN=HL41_08290 PE=3 SV=1 ---MEKILIATDGSQAAEKAAKLGVKWAKIFNSKLYGLSVAEVIPLGPELmevypklieileKKAYEAVDfikkEASQegLTCETFVLSSsDPLEIILDKVQRLGISMLMMGRKH-------TLGRVSRSLIGKSPSPVTVVP-- ->tr|Q7UER0|Q7UER0_RHOBA Uncharacterized protein OS=Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) GN=uspA PE=3 SV=1 -----RTLIGIDSSAPARDALQALSKSTLAEACEVSLATIVPEPPLYTIDDtsmpwipqEVFDSRLEIEntqlkqlQqefgeRfsSCEFSVSQGHPGRGLIEMSERFDADWIVIGSVGHSAFSRILLGSTSDYVANRSTRTCLVHR-- ->tr|A0A0Q9U9Y2|A0A0Q9U9Y2_9MICO Uncharacterized protein OS=Terrabacter sp. Soil811 GN=ASH01_11225 PE=3 SV=1 ----GEVVCAIAGGDGEEHAARVERIVSAASRIAVACSASLRLV-----tvtrggVSDAaRQRIPYAvaSLtsrhpaLVVTVEILTGDPVTVLAEATR--HSGLLVVGAPLRGGATAVLSGQASYRLIRDATCPVMLVP-- ->tr|W5TKI3|W5TKI3_9NOCA Universal stress protein OS=Nocardia nova SH22a GN=NONO_c49000 PE=3 SV=1 ----RPVAVGVNDE---NAPIDLAFDEASLRGVAVMAVRACDEMAGAF-awtgepgrIRTDeTRALTEHlaPWtrrrpeVGLTTTVVFDNPAHALLEQSD--DAQLIVVGRHGWNGLTAMAGRSTRTTLLHRSLCPTLIVPE- ->tr|A0A1E3SV79|A0A1E3SV79_9MYCO Uncharacterized protein OS=Mycobacterium sherrisii GN=BHQ21_12540 PE=3 SV=1 ----LPVLVPVESCPSCEVAVDVGFQEASRRGVDLVTVYSPNRAIQRERfpvaggVLAPiGELADEYlqPHrgrypdVTVRSVQSYACSDVPLREVSR--ATQLIVICDRAAQGFSGLRLGPLTCTVLGSVRAPVLVARR- ->tr|R4LEX6|R4LEX6_9ACTN Uncharacterized protein OS=Actinoplanes sp. N902-109 GN=L083_3413 PE=3 SV=1 ---AGPVVAGVDGSASGPATLDVALQEASLRKTSLVALHAWADADMSPLdpphggdgdhrrGLARGQRALAealAGAgerypdVAVRREVLHGDAGMLLTAWSQ--AAQLLVIGDRHHHGPGSFALGPVGRRLIFHAGCPTTVVNA- ->tr|A0A0K2RCI1|A0A0K2RCI1_9MICC Universal stress protein Rv2623/MT2698 OS=Arthrobacter sp. Hiyo8 GN=AHiyo8_08540 PE=4 SV=1 ---RRGIVVGADGSEESTQAVSFAAEEADKDSQELTVVHAVLAP-PliQ--rvmpasdvaetVLEEERIVLAetvAGLaenypdMVVHQALVsNNEPGKHSWTPPP--MPHCWCWEAvegaaSNASSWDRLP-------TPYSGPCPAQ----- ->tr|A0A0Q9Q7R8|A0A0Q9Q7R8_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil777 GN=ASG88_15200 PE=4 SV=1 ---RRV-VVGLRWPPhEDEALLEEAFAAAERWHCDLEVVHAGRAQGSrrDPPtprghdpgWVPGLTALVEehlVVPrrrhprVHVRVDVVr-SSPAEALMDSVG--PGTVLLVSRT-SDASSAPALGPTSRGVLHLARCAVELVPA- ->tr|A0A0E9N1Q2|A0A0E9N1Q2_9BACT Usp family protein OS=Flavihumibacter petaseus NBRC 106054 GN=FPE01S_02_08090 PE=3 SV=1 ----YNFLVPIDFSHTAKNAAKFAIDMARdLNDVQVTLYHLLDPIaagsdgTPldidL--ddRIKVaEVALSnlatelgA--PANTRTIAADGvFLIDDLAEFVQQEGIDMVFIGLTGASGIEHLLMGSNAIRMANEAVAPVMIIP-- ->tr|A0A1M3IF86|A0A1M3IF86_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 43-93 GN=BGO70_03900 PE=4 SV=1 ----SLIITATDFSTIANDAVHYACRLAHAYNATVTVVHAYNIPvtfnenPMpvm-PIeesRAIAQKSLDemvAslsktYPGLQINSHLTFGDITEGMIDFAKNNKPWMAVVGNSLS-EDDTYWFGGNLLQLMRDTPFPVLAIP-- ->tr|A0A0Q5TTF3|A0A0Q5TTF3_9BACT Universal stress protein UspA OS=Dyadobacter sp. Leaf189 GN=ASG33_06035 PE=3 SV=1 ----NRLLIPIDFSENAEHALNAAKIIAEKGATELLILHAYQPYIadvnltpggvlpgvggadflaMTTdleddyrnRLDQYADNLVAQGYN-ARALWMLGSVQSVVEEAIEEHQPAMVIVGRTGTGGFLDKLIGSSATHIALQSKCPVLVIPP- ->tr|D2B9A2|D2B9A2_STRRD Uncharacterized protein OS=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) GN=Sros_9016 PE=3 SV=1 ----GRVVVGVEGANVERSGLGTAFEEAKLRHATLLAIClcpegled--------tRPLAARFHSTISvweekYPQVNVETMIETRPHTAVMHSAAE--HADLLVVNDREQDDPVELPLGLVSQSLLRGASCTVTVIPS- ->tr|A1T5M8|A1T5M8_MYCVP UspA domain protein OS=Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1) GN=Mvan_1649 PE=3 SV=1 --ERPRVLAAIAPDTGFrdtatlnRTVVEYALSMAAIEEGVPVLLQAFKP-LVLHV---ThdldvetqdvveqrrtevIadlhRMVRDLGEDprEVEVNANLGSIDHVLPDFIVSRGIDLVVIGVSGRRGLARWIFGNSAERLLPRLPCSVLAVKL- ->tr|A0A0Q7EZP1|A0A0Q7EZP1_9CAUL Uncharacterized protein OS=Phenylobacterium sp. Root1290 GN=ASC79_18585 PE=3 SV=1 --AFRQAVFATDMSEASAASHAVAVSMF--PEPVYAYLYAFDA-PL--AGL-vEdrgeftadaaraaEkeleAFAMALPVHrdagTPALVTKYGAPARTLCEHVALVGADLVVMTASSRGLFAELLLGSVVKDALECLTSDVLLVPE- ->tr|A0A024IYT7|A0A024IYT7_RHIRD UspA domain protein OS=Rhizobium radiobacter GN=BN949_03726 PE=3 SV=1 --TRDRIVVAIDLSPAASGVLATAVRFF--RPESLVLFHAIEP-TYKNWVD-dKeaysrqiskeaVkqvrSLSDDFTQHggarEIQIVTLEGDPVQQLAAYVDDNDIDLVIAGTEGRHQIMNLFVDSVAGHNPHEVQCDIMIVPR- ->tr|A0A1Q8TAY8|A0A1Q8TAY8_9GAMM Universal stress protein OS=Chromohalobacter japonicus GN=BTW10_12815 PE=4 SV=1 --AWQDVLVPVDFSLASRHTLRDVLTHF--PQARLTLLHAWHL-PGddemGSDSGYArwrerelaarrirlEaeidKLMEEVGD-vpELELVLEQGDPGEVLMDYLRRQPPDLLALGHQDLALFGRHQPAPLIERLLAEAHVDMMVCRA- ->tr|A0A240UPD6|A0A240UPD6_9GAMM Universal stress protein OS=Kushneria marisflavi GN=B9H00_07590 PE=4 SV=1 --DWQDILVPVDFSLASRHTLKEVLMRF--PNVRLTLLHAWDM-PVamelCEGTNYQhwrdlerqrlrqqlEleteRLMADLHA-kpDLELVLQQGDPSQVLLDRLRQQPPDLLALGSHIRVGIGRAT-DSLLERLLTETRGDLMLCRT- ->tr|Q020X8|Q020X8_SOLUE UspA domain protein OS=Solibacter usitatus (strain Ellin6076) GN=Acid_3539 PE=3 SV=1 --GFHQVLCAIDLALHSREVLAWADWFAREYAAALTIVHAIPSAATrrggfyFDpdFgVELTRH---A--SERIEllkedlnikaaVDIEGGETPLVVANAAESLKASVLIIGR-GSTPRAHGHLPTNAYAIVRESPCPVFTI--- ->tr|A0A1Y1RDZ7|A0A1Y1RDZ7_9BACT Uncharacterized protein OS=Candidatus Cloacimonetes bacterium 4572_55 GN=B6244_13325 PE=3 SV=1 --DINHVLFPTTGSALCYHVFPYALDVAYRFNAKLTLLHTIFDSGPrFTdrIfPTHHFNl-DSL--RDDQVeqVTVYAETAADGILHYSRVNSVDLIIMPSKLARGH---HLGRTTDAVLVGSECPVLTVNP- ->tr|A0A1Y3XWX6|A0A1Y3XWX6_9ACTN Uncharacterized protein OS=[Collinsella] massiliensis GN=B5G02_04375 PE=3 SV=1 --YFRNILVPYDESDHALSALHTALAMVGDePDAKVHVVTIiparALPGVPFTgdgfdvsptvvnpesydqLMDVLVSrtrtDLQQ-VVkeslDGarckvSVDAVIDASPVEGIANYVENNNIDLVVMGRRGVGALRGM-LGSVSYGVLRSVDVPILTV--- ->tr|A0A1F8RZF7|A0A1F8RZF7_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_70_13 GN=A2V84_05320 PE=4 SV=1 -MAGMRFLFATDGSTGAGQALRLLTSSFEPSGvESVEVISVVPLVLRgPDAGpsdaahavieqgqRDAaeqhvhgaAELLRGAGFEAV-ETVRVGHPAETIVTHGIAHRADLIVLGTRGLSGLRRRVVGSVSGKVARYAPSSVLVART- ->tr|M0GWR2|M0GWR2_HALL2 UspA domain-containing protein OS=Haloferax lucentense (strain DSM 14919 / JCM 9276 / NCIMB 13854 / Aa 2.2) GN=C456_03136 PE=4 --PYENILIPTDGSATATHAAEHVVDFAASLDATVHVLSvvddRVLgldsratasgnesEQAATDAVDTVVSEAEARGVTNTVRHVEYGTPVEKIRDCIEANDIQPSGWGRWGGVARIVSCLAVSLKRLCARHQCPS------ ->tr|J0S2J1|J0S2J1_9EURY UspA domain-containing protein OS=Methanofollis liminatans DSM 4140 GN=Metli_2190 PE=4 SV=1 ---MDSMLVPLEIHGAAAAMAPAVEEIARLGVERVELLYVinIRETagdpgi--HahdrEVMDGWTKRLETCGVPDVGAEVVAGIPWIEILERAEAAPPSLIVMGSHGRSLIPRVVLGSQTENVLAHATVPLLILR-- ->tr|A0A139CNB7|A0A139CNB7_9EURY UspA domain protein OS=Methanohalophilus sp. T328-1 GN=AWU58_1426 PE=4 SV=1 ---IQTILIPTDFTIESEKLLSCIAELKNTGLKKAILLHVvdIFKSqglapMFEenakKKIAEYKQLLEEMGID-TVTHVVEGDVNKTIIKVADEENVDCIVMGATTSGVIKGKLTGRTTNYISRRSDKILLIEK-- ->tr|M1E8X6|M1E8X6_9FIRM UspA domain-containing protein OS=Thermodesulfobium narugense DSM 14796 GN=Thena_1837 PE=3 SV=1 ---IERVVVALDFSEQSSKLFNAVNDFKRFGIREIHLVHVvsPDALevnkei--VkiasDHFSLYIKNYLSEGVN-VFLEILIGNVVEQIRDYCEEINANLFFASEHGEGFFKDIFVGSNLFNFIRTIKRPIYVER-- ->tr|D0LIT9|D0LIT9_HALO1 UspA domain protein OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_0327 PE=3 SV=1 --GYQRILVGMDFSSTAQEALRYAVALAAPGAVvDLLHCwrlplASVPYFPAGDVgasIEGPLrTYTEElgqklasehsTPTCAVNYHSVEAAPTQGISEWLEARPYDLTVVGSHGNRGMRRFLLGSVAEATVRHANTSVLVVHA- ->tr|W0JM47|W0JM47_DESAE Uncharacterized protein OS=Desulfurella acetivorans A63 GN=DESACE_06730 PE=3 SV=1 ---LSKLLVAVDSSPYSTNAIKFALDFGKKFDCIVDAlhvvdtmqlegpfiydlSGVLGFEPfinfsaelkktleekGRSILQAFSEMAQNENVKF-NSFIEVGIIPITIVETSY--EYDMVFIGKKGInASFERGILGSNIESTIRKIKKPIFVA--- ->tr|A0A1G3Z2V4|A0A1G3Z2V4_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium GWC2_42_7 GN=A2007_05095 PE=3 SV=1 ---MEKLLVCTDGSHDSEVCYAYAAWLAKRTHALIDVlyvsdlrqfemsmvtdfSGSLGVQPfqgvfsqlqdiekekTKLIGSRVHKVFKKYGIEE-DRVKfhqRTGFLTDCFeeFSEDTE-GFDVICLGKRGEnARIATEHLGSTMERVIRSATKPCLVT--- ->tr|D5AWB8|D5AWB8_RICPP Universal stress protein UspA-like nucleotide-binding protein OS=Rickettsia prowazekii (strain Rp22) GN=uspA PE=3 SV=1 ---FKNILIPIDLNDKksIKSIFPKALMLAINFQAKLHFMYvipefgtkmfeDYLPKNWRIeKKEKYQTQIKDIIKQYipdtieTDNYIGSGAVYDEIIKRSNEIKADLIIISAV-RLQLKDYMLGPNASKIVRHSDISVLVLR-- ->tr|A0A1A8T9R5|A0A1A8T9R5_9GAMM Universal stress protein F OS=Marinomonas spartinae GN=uspF PE=4 SV=1 ---YKCILVPVDWGHEhsWQSLLSASIDLARRHHAQLMVAFidpnsdtptlaNFLPKGTSHl----LEERPNPFIAEHisknirVPFQAEQGQIYSEILYIASVLNIGLIFMALH-TPNLANQLIGANAKKVVRHPQYSGMVCK-- ->tr|A0A1V3ISZ7|A0A1V3ISZ7_9PAST Universal stress protein UspA OS=Rodentibacter rarus GN=BKK50_00290 PE=4 SV=1 ---YNNLLLVIDLNNPatAKTVVDNALQLTANNpEAVYRVVTivepvddsfisAFLPKNFDKsLINEVKNALHRFTEKHfpitakVQHIVAHGTIYEEIIRISEEKAVDLIIMLASSKSsvK-----FSNNTRRVVKYGTKPMLILK-- ->tr|A0A0J8YH01|A0A0J8YH01_9BACT Uncharacterized protein OS=bacteria symbiont BFo2 of Frankliniella occidentalis GN=AI29_05400 PE=3 SV=1 ---MNTVIMAIDHQNNlSATIGQLTLQEALLRNASVVVLcclpTEGGVegEVmniecaidqvvqQYgqpkdplncaeTAVRAALVLFQQSGI-LAWGLLCRGEPAAVIVEQANKLSASMIIMGRRHLSLFNRLFKGSVSAEVLETASCPVLID--- ->tr|A0A0W0WWG1|A0A0W0WWG1_9GAMM Universal stress protein OS=Legionella nautarum GN=uspA_2 PE=3 SV=1 ---YTTILHPTDLRENHFDMSKQAVQIASQFNAKLHLLHVIEPPATYQLaqglgftelavpvKEDAETVmkylGEALDIPPEQQHVQVGPIKQQIMAMVNNLGCNLVIIGSHTPRAV-PAFLGSTAYAVIHQAPCDVLTIRAQ ->tr|A1RV78|A1RV78_PYRIL UspA domain protein OS=Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) GN=Pisl_1709 PE=4 SV=1 ----RRILVPISPMNPvrLRELLNVAADFGERYGADIVFLYVSISENDptaEQLKTTVEEFMN-K--KGikHFfkvrkM-GEGETVASEIVKELSENSYDMVILLSRGYYGASALLYNSTSVAVALAANTSVLIL--- ->tr|A0A101XFW2|A0A101XFW2_9CREN Uncharacterized protein OS=Thermocladium sp. ECH_B GN=AT710_08665 PE=4 SV=1 ----RHVAAVLDGSRASLRALPVLKDFAQRYGSRITVIYQGSDDEFl---SLVKESMS-GAGIT-YTv------EKPSDLLEFIRNKAPDLLVLPLEGRTGAEALESAGPILSALAYTESSILVL--- ->tr|A0A1Y5DFB3|A0A1Y5DFB3_9GAMM Universal stress protein OS=Marinomonas sp. 42_23_T18 GN=A9Q77_08705 PE=3 SV=1 ---VKTILFACDLEDKTQESLALVMSLAVTQNAKIIFMHAiepmnhqaqsminnYLPIKELQALRqDALNsvkdametQITIFyenhaaetkLTEKPEYLIVQDDASSAIKHAIKDYQVDMVVMNSRTHSKLGQMIIGSTANKVIHQSKVPVLVIP-- ->tr|I3ZGU7|I3ZGU7_TERRK Universal stress protein UspA-like protein OS=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) GN=Terro_2200 PE=3 --DAGPIVYATDFHEGVEESMAYAAFLSHQQQVPLHAIHVLPKSSI-DtknhiVA-KIMQtalaDLqItsGKEALQPSSHAVFAkDVSKAIVEYAREVHASAIVLGVNRRSSFASHLPLRRTSRVVILAPCPVFTLAH- ->tr|A0A0P1J4X4|A0A0P1J4X4_9GAMM Universal stress protein OS=Alcanivorax dieselolei GN=BN2364_3825 PE=3 SV=1 --ALEHVLMATDLSKYASGAENLLRELSTQAKRIDLLtVLTPDGLnntPAlpVMALAALNHIRDYLPDEAgeVSVLTERGAPAETILRIAAERDCSLILIGKHGQGWLESKLVGTTATEVCEAAQRPVLVAP-- ->tr|C5A3N9|C5A3N9_THEGJ Universal stress protein (UspA) OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) GN=uspA-1 PE=4 SV=1 --IFSRPLVALDFSKCSIRIVKTVKKFEELIESGILLhSVDYGGIdelEHniEIARKNLEKTAKGIKAE-FELEVMVGTASQAIIGTALAKKATIIVIGKKGRSFLKDLILGSTAERVMRDSKIPVLLVP-- ->tr|H0J6E2|H0J6E2_9GAMM UspA domain-containing protein OS=Halomonas sp. GFAJ-1 GN=MOY_16078 PE=3 SV=1 --SYTTVVLATDMSAAASKAERLFHSLALHFQHRVAIiAESLLETdgyGFEEAQLHLTALAARIPKL-DT-VIVAGEFKQAIINEANAWHADLIIVGQQGHSRLRERLLGSTAKALLEGAACPVILVP-- ->tr|A0A0C9MH31|A0A0C9MH31_9FUNG Uncharacterized protein OS=Mucor ambiguus GN=MAM1_0021d01840 PE=4 SV=1 ----RRVLIGYDHTEVSNAAMEWIVnKRAVFADDEITLAIIVNDdaiaveGtfglesavagPAGWladDYReriskverESTAAlnavvkwFASKGIT-VVPRILSGEPGETLKDFAEANKVDLVIVGSRGLGFFKRyVQRAEILPeQPTEHIylKIGNLLAL-- ->tr|A0A0A8WNC1|A0A0A8WNC1_9DELT Universal stress protein OS=Geobacter sp. OR-1 GN=OR1_00553 PE=3 SV=1 ---FDNILFPTDFSEGAERVIPYLCKITSEMKSPVTIFHVIAETEIDpakkeqredterFLLDAKRQRILKGCgsgnasepasgevtenscesIQGISVELAWGNPGQQICTKAIEGIFSVVIMGSGGKGVTKEFFLGSIAKEVARHADVPVIFIP-- ->tr|A0A126V0V3|A0A126V0V3_9RHOB Uncharacterized protein OS=Halocynthiibacter arcticus GN=RC74_09655 PE=3 SV=1 --KGCDVMIFLEGAHVETSAPFHAQKVANAFSGKVVLVHIMADPhDGkgpid--pvdwdiKKQKTMKDLAErarpfagEDGPECEVKLLEGQCIGQVSDFVDHRQGGIAA---ALRSTDGLgWQSSDTACGVLLSQSAAILMIPA- ->tr|L8M5Y5|L8M5Y5_9CYAN Universal stress protein UspA-like protein OS=Xenococcus sp. PCC 7305 GN=Xen7305DRAFT_00049870 PE=3 SV=1 -------MIAVEKPPLAFKVADTGFALAKALNAQVLLMHINPPALLYSpdsgtspdqikyqMNREAENflqKLvKLYGDnLEVSSFILEGNTEHEIIKAINDIKPDILILGTHGKKAWQELLLGSVSEDIIRHSTCPVMLIRE- ->tr|A0A061N3J7|A0A061N3J7_9BACL Universal stress protein family OS=Geomicrobium sp. JCM 19055 GN=JCM19055_1562 PE=4 SV=1 --AYQNILVCLDSENEpTFHAYNEAISFAKNESATLYLCSIINTKAYGAMSRYDknlvpqvkqmatdylshlHQKATTAGVNA-KLIVDTGLPVQKIVKsVVPRYNIDLIIHGATGGNKIEKALEGSISKGLIKKKPSRLFSCKA- ->tr|A0A1V5SXW2|A0A1V5SXW2_9EURY Universal stress protein OS=Euryarchaeota archaeon ADurb.Bin294 GN=BWY45_00816 PE=4 SV=1 ---FTKVLIPYDFSDDAEYIIRCLKNIPRIREVILVHVtrSLYLVSSPERenpEADYARLRlekvrdlIEMPRSKvrIIVEEITGGEISDAVIRVAEREQVSLILMGRRGRGVIETILLGSTAWDILRFCPSSLLLIH-- ->tr|A0A0Q8QMS8|A0A0Q8QMS8_9BURK Uncharacterized protein OS=Noviherbaspirillum sp. Root189 GN=ASE07_22755 PE=3 SV=1 ---IETILVATDYSEQARRAETRAAMLSVELKVSTLEILavqetrmglntpatasQSTELDTTavdNVLVENrlpVSLIQSVEALQCIRSLAVGKPASAIARRADELNADLTIVAARSKTFVPDFFTRDDNDELVRLCNRPVLLVHT- ->tr|A0A1M5LAU9|A0A1M5LAU9_9BURK Nucleotide-binding universal stress protein, UspA family OS=Massilia sp. CF038 GN=SAMN05428948_1307 PE=3 SV=1 ---SKKMLLVTSEACLSQRAALRAALLSGDLQLDGFDMLnikrsalglcagNTEYSQIevrGhavSAWIDGkrtpvd--VLDDANVLAPIWHTARSTAAELVAETARAQRAELTVLAPQRRHSLLALLAPSHSRAILRQSQNSVLFVHC- ->tr|A0A0K8PHZ8|A0A0K8PHZ8_STRAJ Putative UspA domain-containing protein OS=Streptomyces azureus GN=SAZU_2257 PE=3 SV=1 ----NRVVVGVDTDDASLQALDVAFLEAGLRGARLDMVHCASDTATSPTGAVttvpvdptwvrSGQREffdtELGRRrdrhpgVEVNLRIEHASPGQLLVEAST--GACNTTASVLSRhtgydADITRAILQACATA---CEACADE-CSA- ->tr|A0A0Q5ADI8|A0A0Q5ADI8_9MICO Uncharacterized protein OS=Rathayibacter sp. Leaf294 GN=ASF42_13820 PE=4 SV=1 ----AQVVVGVNGSSASLAALEFAAAEADRRRETLLVVRSWHLPAVEEdsadrpagrvaHELEDHRLRvLdaVAPVreqfprLRVELRFAHGDTVQGLLASAS--DAGLLVLGTDASA--LRRAGERIGHALVLTTHTALAVIPP- ->tr|A0A101FTJ8|A0A101FTJ8_9EURY Universal stress protein OS=Methanosaeta harundinacea GN=XD72_1476 PE=4 SV=1 ---FSKVLCTTDFSEASKSAISVIRDLK-DAVGEVILEYVVSRGETQeeieGYVAEAKEKletikedLVGAG-LKVRTHVDVGNPRDQITRAVLWCLRHHSFENHTG--------ISIYMFDLNPSHQGANLNY--- ->tr|A0A125QJR7|A0A125QJR7_9SPHN Uncharacterized protein OS=Erythrobacter sp. YT30 GN=AUC45_10555 PE=3 SV=1 -SPYRHLIAGTDFSANSRYAILEAAKRFP--NAQLHVAHGW-RVPFQGFQRdtyvreeieeDARSAMEAfmadlakanPALANATSNVAKGNAYEVMAREFdaycDIGGEGLVVVGSHGESGFRQAALGSQTSDMLRYLQNDVMVVNT- ->tr|L8JSU8|L8JSU8_9BACT Universal stress protein family OS=Fulvivirga imtechensis AK7 GN=C900_02169 PE=3 SV=1 ------------------------MEMVARAKAEVVVLHAayvpvlYDPGYAggtplaydisflNRIEEDTKRGYEKMknesGVRGVSVSLDivHDNLISAIQHHVDRKQTDLIIMGTSGASGIREVFIGSNTEKIVRFAQAPVLAVH-- ->tr|A3CVG2|A3CVG2_METMJ GCN5-related N-acetyltransferase OS=Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) GN=Memar_1433 PE=4 SV=1 -----KVLIPTDFSAASVTMAERVGEVPGVREVVLVHAQRSAALssADEDALRRMRELVQRQGFPVEVVvAEDDGTDLpARILRTALATGANLVAMGVRDQGLLRNLFSGNVAATVLRDARVHVLIVPQ- ->tr|A0A0W0SKE5|A0A0W0SKE5_9GAMM Universal stress family protein OS=Legionella cincinnatiensis GN=Lcin_2100 PE=3 SV=1 --AYNRIVIATDLTEASKETVQFTFNRFPKAIFQLLHIiNIHnqqffnptdiseefvdpKQPKTKSIFEKLDDFLNQCQVDksKFEKKIMGGYYADCIIRQTQKWNADLLAFGTQSKSRLHYLLMGSVAKRILHLSTVDMLAIP-- ->tr|A0A1I7G2U8|A0A1I7G2U8_9PROT Nucleotide-binding universal stress protein, UspA family OS=Nitrosospira multiformis GN=SAMN05216417_10396 PE=4 SV=1 --KYKHVLVPVDFSKNSLNALEMALKAVMDASIHVLHAvEMPlgqkmkqagfdaeqvehfRSQILIHAREGMEKIVSDYAHGdrRVASLIEYGHAPDMIREKAQALDIDLIVIGKRGQTELDEALFGSVTKHVLYETPCDVLVVN-- ->tr|A4BHU3|A4BHU3_9GAMM Uncharacterized protein OS=Reinekea blandensis MED297 GN=MED297_09416 PE=4 SV=1 ---YQHILAPIDVSVptIGEQILEKALFHLRYGNADITLLAVAPVKAD--enAIDEIRSQlmafAEHHIaanEGRIHLKVSQGLPSDQVLKTATDIQAGAIFIGSHR-GGgsqLGRPTLGSTAAKICSQAECDVVVV--- ->tr|A0A1W6PGG7|A0A1W6PGG7_RHIET Universal stress UspA-like protein OS=Rhizobium etli GN=TAL182_PA00100 PE=4 SV=1 ---YRTIVCGIGMDSrqTAKHLLRRAAALVD-EGGTIVVMHVIENIPRHHltdipeefeaaAIIDAERKlaslCKGAGhsgdd------RGSH---RRCRLAARV--GRKGESHPGVI-PDITDYVFPSIVEKVVRHAGCSVLID--- ->tr|A0A0F2ITJ7|A0A0F2ITJ7_9BACT Universal stress protein UspA OS=Candidatus Magnetoovum chiemensis GN=MCHI_004097 PE=3 SV=1 -NLFDKILICIDNGRLSDVMSDMTTKIAAGFGSAVVGLHAYNAVmhedafrimeptlpAQYqkeeilQKQRNSHTdlisvgmekislsylkpieqIFNGAGIE-YRSKVKEGKNFKALNQMIAEEDGDLVVIGSSSFNGNgngnGKGYLGSVCLRVLRDSGrRDVLVVK-- ->tr|A0A143PTH8|A0A143PTH8_9BACT Universal stress protein family protein OS=Acidobacteria bacterium DSM 100886 GN=LuPra_04718 PE=3 SV=1 --AMEEVLAPIEFHDHAFDDASLADRVARASHARLRLlhvvaggeE----SRwtvlqPtMaslledeLSGLRasvtGAAHQALERLAESLGGTPgptlevve--GPVAERIAQVANRAEVDLVVLALRGVPGLLGTRVGTVAYRVLCASPVPVLAVPHE ->tr|M7DGU3|M7DGU3_9ALTE UspA domain-containing protein OS=Marinobacter santoriniensis NKSG1 GN=MSNKSG1_03245 PE=3 SV=1 ---FNKVLVGVDFSPA-ESAlLSCLPELKRWGTDTLVMahmvPVGYTSISGYgheadylKDLEKTAEPLRQAGLTV-ETLVRdSTHPAKAFAALAGEMDANMILVGSRSHNFLHKLFLGSFATEVLQHSRVPVLIERI- ->tr|A1WZS8|A1WZS8_HALHL UspA domain protein OS=Halorhodospira halophila (strain DSM 244 / SL1) GN=Hhal_2427 PE=3 SV=1 ---FDHTVVAVHFESP-YQPlLDAVSELHKFGAKQFTLvdvlRIDDPDDLSEghraearRRLAQKQSDLQAAGYQV-DIQQPIGFPAPELAKIGRGYGAQLILLGSRGEGLLREFYHGSTVLELARQTALPVLMERI- ->tr|S0G1B8|S0G1B8_9DELT UspA domain-containing protein OS=Desulfotignum phosphitoxidans DSM 13687 GN=Dpo_1c02770 PE=4 SV=1 --KVQNILFASDLSVDMKPVFEQAVTMATYTGANLIVLHVmeeaspsaqrqvkmAFGENLYKEIRAKHksgaqDlligknvdalrirqaiagFFEDHEKvSADAVSPikkilvaESHSIADEIVSSAVDEDCAFIVMGCRQQGLVAQAMGDKLVRKVLKRSSVPVFVVPR- ->tr|A0A099SES6|A0A099SES6_9FIRM Uncharacterized protein OS=Desulfosporosinus sp. HMP52 GN=DP73_08025 PE=3 SV=1 ---YHKIVVPVDSAGHSKNALIHAIKLAQQTSSKPMVIYinpiipLYLnfglvPVRKYVPLENsdAldilKDIIADMGipPDAIDRRAATGDPTTLIIKIAAEERADLIVMDNKLFGRLAGF--RNISNSVIKHATCPVLVVK-- ->tr|A0A0A2RPZ3|A0A0A2RPZ3_MORMO Universal stress protein G OS=Morganella morganii GN=LR61_04095 PE=3 SV=1 ---HKVILVPIDLNHNYLtdKVISEINEFSVNKNTHFYFLTVISPAEKYNeygvgypmitEdTKFEDETSKTIekelkevvSkfgipDNQVSLLVKIGSAADIIIDVSQQIKADLIIIGSRNP-SFKTHILGSTASSLAHYAKTSVFIV--- ->tr|A0A1H5VSY5|A0A1H5VSY5_9BACT Universal stress protein family protein OS=Bryocella elongata GN=SAMN05421819_1297 PE=4 SV=1 ---YDRIAVIYDDSPESTRALSAALPIARMFNATLEVIVMmartpAYTAYAQAVIPeagellaedriasygglqeRAMKSARDAGV-EPEFHLFESDEHHDVITRLKDSKTALLILGLHHKGPVISRLWRSVY-SFAEDAPCSVLGVH-- ->tr|V5XJR2|V5XJR2_MYCNE Uncharacterized protein OS=Mycobacterium neoaurum VKM Ac-1815D GN=D174_16925 PE=4 SV=1 -----PIVVGIDRIYDPTSALTSAFDVAQRKAVGVVALHRGDAERAL------------lREFqqrfptVPTvwSCLRSHRRYQAAAIEECS--RAQLFVVPAGCMRGM----AGRVVMNVVHQARVPMVSVT-- ->tr|A0A1K6C921|A0A1K6C921_MYCTX Universal stress protein OS=Mycobacterium tuberculosis GN=SAMEA2682775_03682 PE=4 SV=1 -----WIVVRMTDAPDNEAVLEYAAREAKLRQAPILALGGRPEELREIP-----DGEFErrvQDWhhrhpdvrvypit--------------TLPD-------------------------------HHSHGYCPVPGRP-- ->tr|S9QF85|S9QF85_9RHOB Universal stress protein family 4 OS=Litoreibacter arenae DSM 19593 GN=thalar_02482 PE=3 SV=1 --PYARAVVATNGTDEALDLMRFVSQQLPGVKLRLLQVVHIPRQLKEAMLRTGAGKVafadhreqlilkaeehlRllVSKsDVSIQPAVAKGDPAKTLVAYCQDQNMDLIAMGQARKNLVSRAFIGSVSRRVLRDADCDVLIS--- ->tr|A0A117LBZ9|A0A117LBZ9_9BACT Universal stress protein family OS=Thermodesulfobacterium commune GN=XD67_1102 PE=4 SV=1 -----RLGCLIDFSETSKSCLKMASLLSKKDVLEISCLNVIQPPDFLKKTVltsdliEEEKEQRYALWkkli-ANFSdeqdfvqkikfEVMVGNRLEKIEEFVKNQPIDLVIMGKKGKMVQKG--LGSIAREVVRRIEIPMLIVD-- ->tr|V4Y949|V4Y949_9ARCH Universal stress protein UspA related nucleotide-binding protein OS=uncultured archaeon A07HN63 GN=A07HN63_00943 PE=4 SV=1 -----RAIYATDLSAASEAAIENetcLGCLD-RIGIEEIHLVTVIPSNMHVgmpgmkykerrqaGLDRYAGVMEAAGFD-TETHIMRGKPFRRINGLAESEAADVTIVGSRGQSPLENRVIGSTARNLSRTTVVPLLVN--- ->tr|A0A1F9PAW1|A0A1F9PAW1_9DELT Uncharacterized protein OS=Desulfobacca sp. RBG_16_60_12 GN=A2139_05820 PE=4 SV=1 ---FKTIVLATDLSSAWDEIVACAGEFKALGASEIILThvitVLFLGGMDGalraeaqPKLEKQKQFLQGQGFKVSVEMP-VGLPAFSLNDVALRHGADLIVLGSHGKSLWREAVLGCFTCAVLYHTQYPTLLLN-- ->tr|A0A1V4Y4N1|A0A1V4Y4N1_9DELT Putative universal stress protein OS=Syntrophus sp. PtaB.Bin075 GN=A4E74_02028 PE=3 SV=1 ---YEKIVVASDLSEAANHVINSIQDLKKFGTREVILFhalgIRHFHALQYdlarfaePALAEQEELLRRSGFSVKVAIG-PDGVVRELQKVVEEEKASLVVIGTHGRGMAFDALIGGQAHKIMHSATFPLLVIR-- ->tr|L0GXL2|L0GXL2_9GAMM Universal stress protein OS=Thioflavicoccus mobilis 8321 GN=Thimo_1966 PE=3 SV=1 -SLYQHLLLAVDFAPESEPVVARAERMRDRFAARLTLLHivesvpTAieyMPMSYssdgilpdgLELEGELLRaaRTQIDaVGERLGVppgdrLIKIGTTGYTIDETAAELGVDLIIVGNKGRHGLHALLAPSTSKAVLRAQNCDVLCVHL- ->tr|A0A1M7Y8Y9|A0A1M7Y8Y9_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_02698 PE=3 SV=1 ---MQTILAAVDVSRAShlaFKqalvlassmrAELVTVAVTPRyeGNMNRLTLkdad-TKMSVPFLKCLEDAADYAASLGLKIStvHR---VGQPSEEIVRVAEEVNAKYVLLGSPHRSQVERVLLGRTIAKVIEESPCDVLLIPE- ->tr|A0A126ZC68|A0A126ZC68_9BURK Uncharacterized protein OS=Variovorax sp. PAMC 28711 GN=AX767_10525 PE=3 SV=1 --HYKTILAVTDLSASGNEAVQRAAVVAANCGAELRLMYVpvadnpVWPYYGAHLSELARTVASAAGLSVRV-ARRCGASPEDI--AAEANCADLLVSTYRRERQVGTFFKGEWHQRVMRLTRCPLLLTR-- ->tr|A0A0A1VKM0|A0A0A1VKM0_9BURK Uncharacterized protein OS=Acidovorax sp. MR-S7 GN=AVS7_03454 PE=3 SV=1 --AYAHVLVAVDFSAASDALVRYAGGLEAAAAVELFHAADRRcESTAqaLRDYRhevrrQAQGRRVRLsDVFEARRNRvgmavGAGDRARQLAVQQESAGADLVALAHRRRGLLGDLLRGRATRRVLDGVGCDVLVYP-- ->tr|A0A1V2NLN6|A0A1V2NLN6_9MICO Uncharacterized protein OS=Microbacterium sp. CSI-V GN=CSIV_07420 PE=3 SV=1 ----EKIVLGVDDSAAARSALAWVVDRCIQRAAEVDVVhvVGPAEAHttpQQDPLANARRVLRAAVpEQSATCHRAQGGVAKTLAGVS--AHADLLVIGVDPEHPIRAALGGWLPVRVIARTEPPVCIVP-- ->tr|F5SM83|F5SM83_9GAMM Universal stress protein UspA OS=Psychrobacter sp. 1501(2011) GN=HMPREF9373_0166 PE=3 SV=1 ----ESFMIAFDGSETAKRAVQIICDNEIAKnlVGHIVMVDNKDT-ANETELYKAHKKMSDEGFN-ITAHLIdskkIGDgdVVSALTSFRNDHNISIFVIGAYGHSKWRRFFVGSTTTKLLTKTTAPVILL--- ->tr|A0A0F9R2J3|A0A0F9R2J3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0629130 PE=4 SV=1 ----RHLMLAYNGSPLSKKAIDIINKDMFsTQslNIHIVSVQKNNE-DAQQLVNEVETALSSSKCI-VKTTALTGDPLVKLSQYQQEHHIDLTMMGAFSHGKIHGFMFGSFTTQMLLDGDSNYFLL--- ->tr|F5SQ36|F5SQ36_9GAMM Universal stress protein UspA OS=Psychrobacter sp. 1501(2011) GN=HMPREF9373_1169 PE=4 SV=1 ----KTALFGFDNRPTCHALLDWLCSTSLVRnlNLHVVMVGEQTE-RNKEALREAYARLTQSGIS-CKKALIEGRdVTAALMFYQQHHYLEMLITGAFGESRLHELLHGSNTRKLLKASRTPYLLY--- ->tr|A0A0D7F665|A0A0D7F665_9PSED Universal stress protein UspA OS=Pseudomonas oryzihabitans GN=UM91_23195 PE=3 SV=1 ----RQFTIAYDGREATHQGILALARSPLLAgmSGTLLRVGEDDP-ILRKRLDDLALLLRSAGCR-VDTTVAHGDv-ERIVPRHLDERRADLLIMGAYSHSSVWRFLRGSRTTQLLHKTEVPMLLL--- ->tr|A0A1F4MNE1|A0A1F4MNE1_9BURK Uncharacterized protein OS=Burkholderiales bacterium RIFCSPLOWO2_12_FULL_64_99 GN=A3G29_17740 PE=4 SV=1 ----SAFALAYHGGPESLQLVDAVAKCELLHglPCHLVHAGARNA-DIQAEMTQAAQRLADAGVS-THIVIES-GdVEQVMARHLTIQQLPLLVMSAFTHTGWRQKLLGTTTSTLLRRTPTSVLVL--- ->tr|A0A142Y2Z2|A0A142Y2Z2_9PLAN Putative universal stress protein OS=Pirellula sp. SH-Sr6A GN=VN12_15620 PE=3 SV=1 ---ELRICVGIDDSDRSSNAFSKFCEAGWTVPAQVDFVGVVRLPYTYSdipIAIDtsnskksmqaklaqTVVQCQHRFPAA-SIHVEEANHVgDTLVRFATKHHSDLMMLGDTGKGLMGRFLLGSVTRYVLRNAPCSIWISR-- ->tr|B4U6G6|B4U6G6_HYDS0 UspA domain protein OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=HY04AAS1_1621 PE=3 SV=1 ----ENIMICHDGKDEDDKLLDFTKNLNNVYNAKIFLYHADEFGSKkEKLEKLS---K------DYSFelIVEKAIAEEGIVSNAEKLKIDLVIMGSHKK-KLVHFFMGSTTTFVFHYIKTNILVV--- ->tr|R7IIC3|R7IIC3_9BURK Universal stress family protein OS=Sutterella sp. CAG:351 GN=BN620_01779 PE=3 SV=1 ----LRVGVAVDGSAYGEAAVRYTLKHRKlfGDHASFTIINAvndYrgaamtnvtgIALPTlsdkdIDQLEkNefedtvskVRPIFAAEGI-TPDEVKLVGTPADEIAAYARANGIGILVMGSHGYNRLKTAVMGSTAAALAAHGIVPLLIVKS- ->tr|A0A1D2SH06|A0A1D2SH06_9BURK Uncharacterized protein OS=Lautropia sp. SCN 69-89 GN=ABS56_09975 PE=3 SV=1 ---INSVLLPLDGTQVSEAMASQAAGMAQWLGADLSLVQAISPEArpgadipvgdvmESSYVRGRADDYRtRYGV-RTSWEVLHGDPADAIARYLDGRRDVLLAMVTRARRPLEAAILGSVTAGCLQKCGVPIVTRLP- ->tr|A0A0B8QKL0|A0A0B8QKL0_9VIBR Universal stress protein E OS=Vibrio ishigakensis GN=JCM19241_3560 PE=4 SV=1 -----------------HRMVRKTLDLAERLNATPHLVNSYPITPPNITVelpefdptiysdsvrghhlKSMKPFAKSMVSMKSKPSLSKAYHKM-------------------------------------------------- ->tr|R5ESS3|R5ESS3_9GAMM Universal stress family protein OS=Succinatimonas sp. CAG:777 GN=BN779_00568 PE=4 SV=1 -----------------LRLLREAQRLSLFTGCKIALINAITPIIPPVAVdlpgytpdsvydnalkegcKRALSFATRHKIAPNDCHICEGNLDDVIYDECKKLNPTALFIGTSARKGIASALIGNICERVSDNLSCDVVVIT-- ->tr|Q1N6N3|Q1N6N3_9GAMM UspA-related nucleotide-binding protein OS=Bermanella marisrubri GN=RED65_09214 PE=4 SV=1 -----------------EHIFEFSELLNKDNLYKVHLVNSYP---imSMALAslpdtpipedlqqyvleqheEASRELAEKYNIANDLIHIREGEAEEVIIQLTQETDADVVLIGLLAEADFQSVILGSTLEHVLDNTSSDVLGIK-- ->tr|H1Z207|H1Z207_9EURY UspA domain-containing protein OS=Methanoplanus limicola DSM 2279 GN=Metlim_2296 PE=4 SV=1 --LFRRVLYLTDFSEEAKRCIPFIEWMASAKPDQLVILhvqDTRRLWPatqeqinefnekDTRRLAELKEQMNNYGISQIVTELVTGNAIDEILGVADSFKPTIIVMGAKGRTGALKALLGGVAEAVVHRADAHVLVVR-- ->tr|S6BXM0|S6BXM0_9GAMM Universal stress protein A OS=endosymbiont of unidentified scaly snail isolate Monju GN=uspA PE=3 SV=1 ---FKKILYPVDLAHveFAAGFASEVERVAETFGAEIEVMTvmpgfgmaivaSYFPPDAEQRaRREVERQLGEFASSAFSRpvkiRVEQGTHWKRILSVAKEDAVDLVIMPHCDKGWAESVLVGSCAQKVAERAPCSVLLLR-- ->tr|A0A1E5SUY7|A0A1E5SUY7_9BACT Uncharacterized protein OS=Fabibacter sp. 4D4 GN=BFP97_15930 PE=3 SV=1 ----KNIVVPIDFTKQSVTALENAIHMAERLEMGIILMHSLELpAgfstspvvGaNYQNLHVQRDAAQERlhdlikevaIDSNMNctTKVTYGNLSHAIKRITEEHEIGLVVMASSGKSGFLENLTGSQSYNVAKHVDCPVVVL--- ->tr|A0A0M6XRY6|A0A0M6XRY6_9RHOB Uncharacterized protein OS=Jannaschia rubra GN=uspA2 PE=3 SV=1 ----GPIIVATDLSPRSDRAMLRAARIAKEQDAPLHILHILdeeLPAAILHGHAEDaKKTLQsrvdqTPEIADRspRVDIEVGHLSRLLPGILSDRKPGLLVLGSHRDRGLAELIGQPSLSRIMAVSDVPILLAV-- ->tr|A0A0P1IGI4|A0A0P1IGI4_9RHOB Universal stress protein UspC OS=Phaeobacter sp. CECT 7735 GN=PH7735_03621 PE=3 SV=1 --DYTSVLGLVSYSRACATVVDAALTLAPEAEVKAIHALHvpyaGLTGGDTDsemakaVRQEAEAEAAKWLEtvpsenDNFEHTIVTGGLRGILMQTVADTKPDMLAIGAHTRSGLFLHRIGGFAAELVREPPTDLLIAPPT ->tr|A0A1G7QRK9|A0A1G7QRK9_RHOCA Nucleotide-binding universal stress protein, UspA family OS=Rhodobacter capsulatus GN=SAMN04244550_03263 PE=4 SV=1 --DYARVLAPVCFSPSCASALMAVRAIAPRAELRSFHAVPipfsGLTGDGPGsamareLCAEATAERDRWQAsfdqrpDPINIEIISGYLSEI-MARLTVDRPDLIAVGAHTRSGFVPNVLGSFVTDLIVTPPCDVLVVRA- ->tr|A0A158CY26|A0A158CY26_9BURK UspA domain-containing protein OS=Burkholderia sp. LMG 29324 GN=AWB81_04516 PE=4 SV=1 -FSIDRILLCYDGTASGQASLRCGSALVRQLNAEAHLlavlecccgaGGFDPLPAvefdldektAMAILHEGVERLRASTAAAT-GHLLLGNPVDEVSRLANIVRADLIVIGQSPGSAFARGWTSDNSTLLLRRVTCGVLFESA- ->tr|A0A158I9T3|A0A158I9T3_9BURK UspA domain-containing protein OS=Paraburkholderia sordidicola GN=AWB64_05753 PE=4 SV=1 -FDYRRILTCYDGTAEMTAALHHATSLGKSLAAELHVlvvidtaamvaSTLGMPSEgaylniehaARETLRRGLDLAEERGMDAH-GHIAIGNIADNVQHYAQALHADFVVLGHRRRSAFARIWHGPAPhQTLIGRCGASAVITVT- ->tr|T2G9V6|T2G9V6_DESGI Putative UspA domain-containing protein OS=Desulfovibrio gigas DSM 1382 = ATCC 19364 GN=DGI_1090 PE=4 SV=1 ---PKTILWPTDLSSESIASAPKVMALSQQYNAAVVMLyvavdlCSYFPAYGnFPsnevvdhfrlwEIKHARALMEDvcekdfKACPHLELELANGDPVEEIFKMAARKNADLIVMTATHGRHGKDgPGLGHVAEAVATRGALPVLFVT-- ->tr|E9TN36|E9TN36_ECOLX Universal stress family protein (Fragment) OS=Escherichia coli MS 117-3 GN=HMPREF9542_05267 PE=3 SV=1 --MYKTIIMPVDVFEMelSDKAVRHAEFLAQDDGVIhLLHVLPGSASLSLHRFaadvrrfeehlqHEAEERLQTMVShFTIDPsrikqHVRFGSVRDEVNELAEELGADVVVIGSRN-PSISTHLLGSNASSVIRHANLPVPVVSM- ->tr|A0A0S8B2P1|A0A0S8B2P1_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_28 GN=AMS20_06300 PE=3 SV=1 ---GEAVIVGVDATPAGALAAATGWTVARAAGVPCRVVHVtptPSAAPRGgiepaqpdlidGLIADARSHVvdalSGHVPDDVLqtIEVLVGNPAWELRRVVADTSAGLLVLGGKHHAPPVRWFGGSTAHNAVRTIDVPVLVAA-- ->tr|A0A1Y1I1X5|A0A1Y1I1X5_KLEFL Universal stress protein family protein OS=Klebsormidium flaccidum GN=KFL_001700170 PE=4 SV=1 ---ARTVLCAIDGSEHSHRAFHFALHkIICGPEDRVILFHALKPLNIFnhpvilnmtteerAAVVRQSEAaARES-LKVFQEraastgvrtelVVVVGDPREQVSKYVSEHPVDMVVLGARGAADsstpphNNRFRLGSVSSHLVQHCPVPTVVVPE- ->tr|S6A802|S6A802_9SPIO UspA domain-containing protein OS=Treponema pedis str. T A4 GN=TPE_0483 PE=4 SV=1 --LFQNILVIITGSEASINAAKYAILMAKLYRCKVHAIyvvdTATIKqltlNRIFieeegleyknslqetgsRYLSYVHELGAEKNIE-VITEITQGSVSAEVLNYADKHKIDAILLACEDAQTDns-KDMLAKTFHSILTNSECSLLLVN-- ->tr|I6XYH1|I6XYH1_PSEPQ Universal stress family protein OS=Pseudopropionibacterium propionicum (strain F0230a) GN=HMPREF9154_1950 PE=3 SV=1 -----LIGVGLNTSRVNHSTLAAAFEQAQLLGARLEIVHALQPP-IGLfgpklgpadleeLIRFTRGGIEAMaseqiktfPGVPYEVVVVAATPINEFVTRSE--NYDLLVLGA-GEEAIPGFGLGGLLRGLMAHSLCPLYITH-- ->tr|A0A0A2HQW0|A0A0A2HQW0_9DELT Uncharacterized protein OS=Desulfobulbus sp. Tol-SR GN=JT06_18760 PE=3 SV=1 ---FSCPMLATDWSEPSENALDALLAMKgvtqrviVAHNIDSKLTKNRSKTDIRGLeeesrkrLEKYCDTLKKNG---LTAEPHlsFGHTATEIIRLSREHRATMIILGRTGKDWFQEYWFGGVSHRVAENSELPVMLVP-- ->tr|A0A0F9YCL4|A0A0F9YCL4_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0106340 PE=4 SV=1 ---MEKIVVAIDDSEGSFLALTFGQRFAAQLGADLNAVSVVPTqGDTAARLSTLQARIAVHHLGAVTLDVVNHHSAkEYLGELA-SDEDVGLCMMAHGRRPVSEMLIGSVTAGVVRRALRPVYLC--- ->tr|A0A085WLS5|A0A085WLS5_9DELT Universal stress protein family protein OS=Hyalangium minutum GN=DB31_7875 PE=4 SV=1 -----VAMVGVDASDEADGSVAFIRALREVGPCDVIATYVCSPAEErtrlgihspvrvelldpvvrgiqaldpyveRVLVREVRERLGEVpGEGNVEIHlePGYGRRDEHLLHVARKRGVDLVVVGTHQR-VGLQRWWHgSVSAGVMRHAEQSVVCVPA- ->tr|A0A1S2VCB0|A0A1S2VCB0_9BACT Uncharacterized protein OS=Arsenicibacter rosenii GN=BLX24_25335 PE=4 SV=1 ------ILLASDFSDASEHAFRYALNILGYVPCDCTLLHAFPiqletaHTPFY-EADIVQQRSLEMlstLGRQLKAERnyrwhrfapqtYPGNSLSAIQHASGQEKYDWIIVGASGRG--LNPWLGSTSSNLLREARTNLMVVPA- ->tr|A0A087BDB4|A0A087BDB4_9BIFI Universal stress protein OS=Bifidobacterium merycicum GN=BMERY_0504 PE=3 SV=1 -----DIVVGVDGSDESFAALKWAMREASLTGQNINavFGWTHSwdtnsdepdseeswahvRHEIADELRSWVEQASDGidfDPERLKMTSVRASGTSALLQIGK--DSQQIVVGRRSLGRVTRWFMGSLSASLAETAQVPVTVVRI- ->tr|A0A0P7YJL7|A0A0P7YJL7_9ALTE Universal stress protein family protein OS=Marinobacter excellens HL-55 GN=HLUCCX14_01565 PE=3 SV=1 ------ILLATDGSKASFNAQTAFEKLMANQRAGRVVWAHSEQPEQSdeATEQQINELAERLP--NVHRNILIGRPVDQILQTINDTRPLLTIMGKRGSTPIQEIMIGSTTEHVAAASPYPVLMM--- ->tr|A0A0G3M6N9|A0A0G3M6N9_9FLAO Uncharacterized protein OS=Chryseobacterium gallinarum GN=OK18_08285 PE=3 SV=1 -----TIIVCTDFSQEAENATHYAASMAKENEYTLILFTLQSVSIhalnaqasaefFYAQTLKNQKKIADKAAElsdlyriPVNHHLASGNFIEELQNAIHTHNGDFIVMGMTQ-KTIEQKLLGTLVGQTIHRIEKPTLII--- ->tr|A0A218ZRR9|A0A218ZRR9_9EURY Universal stress protein OS=Thermoplasmatales archaeon B_DKE GN=B2I17_09550 PE=4 SV=1 ------AIIAFDDSDAARAALKFSMKFKDVIDEIIVVyvspsligvtptFDTYIPASVYQrqeetsdsIIESAKSIMGNTSSKITFV--NIDSKgetvPRAIMRTAKERGVDLIITGTRKLSGLSKAILGSVSSEIVKLSTIPVLITPPV ->tr|K0NJN0|K0NJN0_DESTT Universal stress protein family protein OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=TOL2_C19120 PE=3 SV=1 ---FSRIVFGTNFSEASMAAFEFAYQLADYIGCKLHIFHALNLDSsgtqnvlgqkqIEDQIQEAKNRIDQEYVSQMHNFDnydiavWEGSPYIELLKFSREARSDLIVMGHNNMYSdPDEVSFGPTIEQVVLRSACPVISV--- ->tr|K8ZMD8|K8ZMD8_9ENTE Universal stress protein family OS=Catellicoccus marimammalium M35/04/3 GN=C683_0484 PE=3 SV=1 -SKYKNILIAIDGSEMSDAVMEAAKEIIHEDSNVYVETIVDYPGTLGAInedaiiesdyekaekdLAEIIARHpdLKLLVKSFVAEVQVGNPHKMLaREIPDELGIDVIVIGKTTKTSLMDKiFIGSTAKAIVADARCDVIVVKT- ->tr|A0A179D327|A0A179D327_9BACT Universal stress protein OS=Thermosulfurimonas dismutans GN=TDIS_1490 PE=3 SV=1 ------ILVPLGKDGSYEALLNFVVCMLKGLPegiVKKVyllhvVSSDALKKasrrdlrleslvkdskllkelyqeylkkEAEPFLAEASEKLKKELPNlPVEEVVLSGDPPAEIARFAYEKACGAEIIARRARSHISEIVLGSCTQALIHRPG--------- ->tr|A0A1B9F883|A0A1B9F883_9DELT Universal stress protein OS=Dissulfuribacter thermophilus GN=DBT_0609 PE=3 SV=1 ------FLLPVDVKKPSYRVAGLVGCLAANLGqrLDSItiltvMAGSYLTShiknidiradrllnsdlikdlrkqhiekEVLPILHEIKEKLVSAGASsPIDEKIEDGDPVERITQVAKEGGYTQIFLERRGVSTAQEIFLGSVSAGLLHKDI--------- ->tr|D2S7D8|D2S7D8_GEOOG UspA domain protein OS=Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) GN=Gobs_0660 PE=3 SV=1 ------AVIGLGEHEDDEPVALFAAEEALRTGRPLLVLHTRSDDggeW-----AADSPRWAErWPDLRLTHTPVPGPTGGRVLAAA--CPTPLLAMTAGHGg---lLHRPMDGLHRWLLRHCTSPMAFV--- ->tr|A0A090J5C6|A0A090J5C6_9BURK Universal stress protein UspA and related nucleotide-binding proteins OS=Paraburkholderia glathei GN=BGLT_01853 PE=3 SV=1 -IGFHRILLCVDSTTVVAASAMLVRTLAGTGAQVQIVGVLENARAAIPlgpladfnqnaaharLLREVNARVAEACQLvnesgaAVFTKVvdliaDGGDAAHAIANAAQTWEADLMILGARHHRGLVRWVERAAGAPDMRIGGCTILVV--- ->tr|R7X7A2|R7X7A2_9BURK UspA domain-containing protein OS=Pandoraea sp. SD6-2 GN=C266_02276 PE=3 SV=1 --------MAVDPAGASQNAVAYTTRLCTHETQVLVLGFFEDPAAFLAphsrtpadmrqafneLQEDELLALERAKVAlqrsgaSVHHRLlgralGNRDISAGIGRVSNEWNADLVVVGAEPADGLIATLTTRVSGVLAEHTHRAILVI--- ->tr|A0A0L0SHN6|A0A0L0SHN6_ALLMA Uncharacterized protein OS=Allomyces macrogynus ATCC 38327 GN=AMAG_07281 PE=4 SV=1 ----YVVLTAVDASAPSWHAVDFAANLVAHLSNYRLLVVYVTAlNRTSRfpyldhldkaynleiqhEAKSAIQECQAYLHRfddnvsyELIEIEGEGEVGPLLEKYIDehVPDCNLVVLGTHGHQGLKKMLYGSVSEYCITHLRVPVTVVK-- ->tr|G2LLF9|G2LLF9_CHLTF Universal stress protein UspA-like nucleotide-binding protein OS=Chloracidobacterium thermophilum (strain B) GN=Cabther_B0433 P ------ILVGVDETPASEVVVAALAARHFPPQTQVKLVTATGVFeyfssdilgssvavvpsdtidelrRtAAEAATAVQEKLLAaypdWKVTLSREV-IEGDPKSVLLDIAEKWPADAIMLGTRDLSGAERFFIGSVSSAIVAHAPCTVEVI--- ->tr|E6YSA7|E6YSA7_9RHIZ Putative universal stress protein OS=Bartonella sp. AR 15-3 GN=BAR15_160083 PE=3 SV=1 ----QRILIAFDGGPLIMKAIDFICTQEFFKNVTFILGMAEQQIQiIQNSFDETLARLQSAGF-NAEPLRTEINFEQMVLHNIEPLNLNMLIMGAFHRSKVHNFLFGSKSQAIIHNTPIPVMIM--- ->tr|A0A1R0F8Y9|A0A1R0F8Y9_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Bartonella apis GN=PEB0149_007980 PE=4 SV=1 ----KKALFLYDSEFKWKLITDYFNHFHLFSDKTIVLACSKYASSsVSEDIEKLVRELASAKI-QVSPLLLDDDRDGENInRIVDENNIDMIILSAFNKDKITSLIYGSIPGSLIQKLKVPTLIV--- ->tr|Q2FQE4|Q2FQE4_METHJ UspA OS=Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1) GN=Mhun_1767 PE=4 SV=1 ---FSRVLVPVDLTPESWTAVEQLAKIPDVGEIIVafVISRGETERELERIRIQAEQDIQERCKQiqtagaEIRHRILEGDLVSRILDYAQEADVSLISTVPTEKGFFAEMLHGSFSCELARLATKPVLVI--- ->tr|A0A1V4ZVQ1|A0A1V4ZVQ1_9EURY Universal stress protein OS=Methanoregulaceae archaeon PtaU1.Bin066 GN=A4E41_02078 PE=4 SV=1 ---LSHLMVCTDFSRPEIVSLSM-EDLPFASRVTLlhVVSTGDTREEVNLHSSDAWTRLKELREAysrlkiPVRATVCEGDTAEEIIRHARENQVSLIVMKSSGKRGFIRNFIGSTTTHVTRNADIPVLVL--- ->tr|A0A1V6AR50|A0A1V6AR50_9BACT Universal stress protein UspE OS=Bacteroidetes bacterium ADurb.Bin145 GN=BWX96_03333 PE=3 SV=1 ---FTNVMLCKDFSSPGIEDLCM-DIYPYVTSVELfhAVTRGDSEEEVNHAVKDAKEELEKVAITcngkdiTCNIHVRVGDAADEIIRFSEEKNISLIVAKSTGRQGIVKKIVGGTTEAIARSARKPLLVL--- ->tr|A0A1M3FT72|A0A1M3FT72_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 46-32 GN=BGO54_00150 PE=3 SV=1 ----KDVIIPVDFSETSLHAARYAAAMLSGRTDTRVILYHMFEEEAeadttEQYLQTLKTELEQKGVSNIECVKELgDDLIDNLGRLAYQKTAELIVMGITEKEEWRQIFSGSKSLKMVQQNVCPVMII--- ->tr|A0A0Q5ADI8|A0A0Q5ADI8_9MICO Uncharacterized protein OS=Rathayibacter sp. Leaf294 GN=ASF42_13820 PE=4 SV=1 -----TTLVAWAGTTAALTALDWAITREYLLDHHVILCHVAAPADERaiskaALDELAATLQQDRAGIRFSAELLHGDPVEQLERRC-RQDGTLLVVGTDTRNEHSGRFENSLGMRITQRGEIAVVIV--- ->tr|A0A1B6XIQ2|A0A1B6XIQ2_9MICO Uncharacterized protein OS=Plantibacter sp. H53 GN=A4X17_00375 PE=3 SV=1 -----QTIIAWDGSDAARRASTWAASRAAATSDALRVVQVVDRSSA-ddgesleravaSTEDEASRLRVLHPELLVRADVVIGDRYAELRGF--SDDTRLVALGTDEYGSPTRSSGWSLGSRLAAASSGPVAVI--- ->tr|A0A081G1I7|A0A081G1I7_9GAMM Universal stress protein F OS=Marinobacterium sp. AK27 GN=ADIMK_1095 PE=3 SV=1 ------IPMDPDHADLFDAQVKAAQRLLA-DGGTISTIYVN---QNYVhhvlaatssdrpteieqaILKQVKALFEAEVPKEqrGHVYSRRG-VvHDEIIKKAKAIKADLIIMAAckKPLERY---FLGSNTRKVMMDASCSVFVQ--- ->tr|A0A0W0Z2S2|A0A0W0Z2S2_9GAMM Universal stress protein family protein OS=Legionella shakespearei DSM 23087 GN=Lsha_0702 PE=3 SV=1 ----KHIVIASDFSKYAEYALQRAISLAERHHIPLHFIHVLQQPLSVDFGQylseqpkdflSLEKEMLDKLSVLIMKYPtnvsvnlsvLAGRAADEITQYTEQNQGNLIIAGAQGQYYINEYVLGTTSSHLIEQGKTPVLLI--- ->tr|A0A068NY33|A0A068NY33_9BACT UspA domain-containing protein OS=Fimbriimonas ginsengisoli Gsoil 348 GN=OP10G_3231 PE=3 SV=1 -----RGVFAVDHREEPEEFVDALLQLKPGGIGCLDVLTINEAGHRELASVSRLPAPVADVCSWIDegirsknvaladrlsslgadcrAVVMEGDmPACAIAIAANRAHADFIVVGAKRHGFLDRHLGRSVSKGLLASDRRALLVL--- ->tr|A0A136KUB6|A0A136KUB6_9BACT Stress response protein NhaX OS=Armatimonadetes bacterium OLB18 GN=nhaX PE=4 SV=1 -----SAVLATDHSPYCDACIERFFSWEANGVRRMTVLTSLDRGTAPQQVgPAEASERLTGSLPDVKdqlrarneelclrfrsegieceSVLVEDHPQSAIAQTMSDTEADLLLLGARGHGFWDRIRLGSVSHYQVVATPHNVLVI--- ->tr|I4BYD5|I4BYD5_ACEMN Universal stress protein UspA-like protein OS=Acetomicrobium mobile (strain ATCC BAA-54 / DSM 13181 / NGA) GN=Anamo_1698 PE=3 S -QMARKILVGVDLSKMSESLIAYSHSIAHRLNDEVIYIHVLPRLsSLWrgyepwippQigdeVKQIAHKKIsywiqkaEDQfkdlPVHEHKILIEEGSPGEVIIQKAKEENVSLIIVAYKGHSTMEHILIGSTTTTIARHAPCSVLIYRPG ->tr|A0A0K8QXC7|A0A0K8QXC7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Bacteroidales bacterium 6E GN=BA6E_106139 PE=3 SV=1 --EIREILCPVDFSDPARRALKNAILLAINFEAKLHILSVFEPFFTTsprfmldsdeeneKLYHefeqRMNQFLGEFDLkrVNHSIEIQKGIPHEKILESIQANGVDFLVMGTNGRSEFSRLIMGSVTEKVIRQLPCSFVTTKT- ->tr|A0A1P8WCF3|A0A1P8WCF3_9PLAN Universal stress global response regulator UspA OS=Fuerstia marisgermanicae GN=Fuma_01329 PE=4 SV=1 -PRFQHILVPVDLTPKNRVALDIAFELATDNKARVSLLHVTQTINtadetlaFYDRLqQRVRDDLeslsqrfSDAGL-AVEVKVPLGQPLKEIVSFAATHQVDLIVMSSHPVDKEdLLQSWGTLSYKVSVACPCPILLMK-- ->tr|A0A0S8KZ47|A0A0S8KZ47_9BACE Uncharacterized protein OS=Bacteroides sp. SM1_62 GN=AMS23_01915 PE=3 SV=1 ---MKNIIIPIDFSEDSLKGIELALLFARKQYTNIQLVYVQKKSSDynspgyfEEENKWAEKKFKeiieRFeprleNDSKLRYIIKSGKIYKEIVSQVESYKEAMVIASTHGASGFEEFFMGSNAFKIISATERPVLTTRK- ->tr|A0A1V6I7Z7|A0A1V6I7Z7_9BACT Universal stress protein UspE OS=Bacteroidetes bacterium ADurb.Bin028 GN=BWX59_00368 PE=3 SV=1 ---MQRIIVPIDFSEESIKGLELGIIYANKFNADLQMVFVQKKKTGrfhielRKQYDAAMEEFEdllrKYkdklhKDCDFSYIIKSGRVHEEVARQAEAFDDSIIICSTNGESGFSDFIIGSNAYKIVQTADRPVITVTT- ->tr|A0A0S8H5N4|A0A0S8H5N4_9BACE Uncharacterized protein OS=Bacteroides sp. SM23_62_1 GN=AMS27_16870 PE=4 SV=1 --SNLNFLVAFDFRPEAEAALDYALVVGRKIKTDIHILYVLEEESPMlKmvltdaqrkMlQRGAKDNLNDiikqksanQDI-KLYPVIKKGKVYNRIVETSTELGSSMIFMGRTDSMDMVKNFTGTNTMHIVRNSDIPAVTLKR- ->tr|A0A1F3K591|A0A1F3K591_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_40_13 GN=A2W88_12905 PE=4 SV=1 --TTNHLLVPVDYSDKSVYGLQMAAKLLKLFGGKITIINVVKGVDPIwTefftdeereSlLAKLRAHLKQfaakyidgQVY-PMDCVVAKGKLCDTILKTAEDLNATYIIMGTSTIDNIKKWIIGTNALRIVTEAKCPVITIKQ- ->tr|A0A1J5APR0|A0A1J5APR0_9BACT Uncharacterized protein OS=Bacteroidetes bacterium CG2_30_33_31 GN=AUJ98_05635 PE=3 SV=1 --TNMNILVPIDFREQSLNALNIAIGLAKTLKLKISLLYVHQDKGALtSlfsseqtaLfDEAVLEKLQDlakinaekNNV-VIDSKlVHHNSVHTAILDYADKNSTEIIVMGRGQ--KDNDVVIGANTLRILRSSNVPVITVDQ- ->tr|A0A1M6ING0|A0A1M6ING0_9BACT Nucleotide-binding universal stress protein, UspA family OS=Tangfeifania diversioriginum GN=SAMN05444280_11763 PE=3 SV=1 --MNKTILVPVDFKQPSADAASYGCKMAQKMGAGLLLLYVIDTPGILaQffssgdHlvkvTDEAKEKLIElaksmnskfPEI-KTSTRIARGKPYEKILETCRNEDTRMIILGENHQCGDPEDELGTTVYHVTLKSRVPVLTLKG- ->tr|A0A1V6I4K8|A0A1V6I4K8_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin028 GN=BWX59_01356 PE=3 SV=1 --SKKRILVPTNFTSETEIAFEQSVLFSLKTDADIILFHVIPSLKMInSnssn-IDRVQEELSIlaekyfkeTGK-NAQTRIEVGKVLQQILMLEKEIKPSYIFLGSDVSK----GEVSSLTLKLVNSVECPIIIFLR- ->tr|A0A1G2WGS0|A0A1G2WGS0_9DELT Universal stress protein UspA OS=Desulfuromonadaceae bacterium GWC2_58_13 GN=A2X84_02525 PE=3 SV=1 --MDDKILVPLNGSSTAIRTVQGIIREKSRFFGILTLLHVIDEEKfsyrmipdFqVemirenarksakHLLEEHQESLQRAGL-RTEIRIVSGSPRQVACRIANDENFSLVILGRRGAGEIRDVLFGTLTNYALHNVRCAVMLF--- ->tr|A0A173MHB4|A0A173MHB4_9BACT Universal stress protein UspA OS=Filimonas lacunae GN=FLA_2887 PE=4 SV=1 ---METIIIATDFSHAATNAALYAAELANALQKELLILYIDTLPVTyadvpiptrlEEMTEMGEMEIKKlqerlilhtTGNISITTEIQMGTFFTTLTSVCERVHPYAVVMGSQGTTASERFFFGGHTVHAMKHLKWPLITVPPQ ->tr|A0A0Q4DRS3|A0A0Q4DRS3_9FLAO Uncharacterized protein OS=Chryseobacterium sp. Leaf201 GN=ASE55_13655 PE=3 SV=1 --SINTILVTTDFSGKSGNAVTMASHMAARHAAHLILFHTVNNYFMtdrtgkqvissetvQDHYLRAEQSlkdlensLRAqHPQLNIEILIKNDTLIAGLNEIIGLRDVDVVISGTSGTQKLKQLILGSMSYEILTGAHCSVMLVPE- ->tr|C6X5L3|C6X5L3_FLAB3 UspA OS=Flavobacteriaceae bacterium (strain 3519-10) GN=FIC_01253 PE=3 SV=1 --ILKTLLVPTGFSAKCENALRLAAEMAQRHDAKIILFHVVPLQYLidrtgrqiiggdttQITIEQAAEKllsykeaLVAnHPGLQIETHVKTGMLPDVVNDLTVSASADLVILGTSGEQKWKQMILGSYSYDILRDAPCPVLLVPQ- ->tr|A0A0W0GJ14|A0A0W0GJ14_9CHLR Universal stress protein UspA or related nucleotide-binding protein OS=Dehalogenimonas alkenigignens GN=DEALK_13600 PE=3 SV=1 -MTYSKILIPLDGSESAELALPYAKMLAE-KTTALVLFSVCPEDeLRlcrlnSAYLGIQAGVLAQEGF-KAISHTEPGDLAEKIKDYVANEHVDLITVCRQGYSDLSREE--KVLHN-LVSENCSLILIKP- ->tr|A0A0Q0D968|A0A0Q0D968_9PSED Universal stress protein family OS=Pseudomonas syringae pv. viburni GN=ALO40_04922 PE=4 SV=1 --MVRSMLYATDLGLYAPYVMQHALALARTFNAGLYVVHVVEPMGLFaesvlqsylgeEalqelhgkgvhaFLEGIEQRmldgFREeLGeghsdLSlIRTVRVVQGEPASVILEQAHKLEVDLLVLGRHSASAQEGASIGRTAARVLQSSGVPVYLVPI- ->tr|K9YFE3|K9YFE3_HALP7 UspA domain-containing protein OS=Halothece sp. (strain PCC 7418) GN=PCC7418_3059 PE=3 SV=1 --MYRKILVPLDGSKTAEAIIPHVKNLAKHDEATVFFAQVIEPATRSGivnfeqeqeitfkpqKLDHAKTylkswqdQFTEEGL-SSEILLLRGVAVDAIVHAINEMDMDLLAITNQGRSGLKKALYGSVSAALLNCAPCPILVGNPD ->tr|A0A0W0GGR0|A0A0W0GGR0_9CHLR Universal stress protein UspA or related nucleotide-binding protein OS=Dehalogenimonas alkenigignens GN=DEALK_05870 PE=3 SV=1 -KQFRTLLIPVAGGPEDEEALELACQLsRALGGIKLVVTNIISIDRSlpldaeveseiakaEGILARFENLGKKYGC-SLETNLLQaRAVAPAIVDEAIEQKADAIIIGSSYKMRYGEFSLGEVVPYLLQHSPCRVILSHH- ->tr|A0A160VBY3|A0A160VBY3_9ZZZZ Universal stress protein family OS=hydrothermal vent metagenome GN=MGWOODY_Clf415 PE=4 SV=1 ---------------------------mARESKTELHAVYIIEVPLElsleaerpedinkgEEILARIEAIASEEKyK-GLQARFLRaRQAGPALVVESEDHFMDLLIVGIPYDRRFGSCNLGTTASYIFNNASCQVMFWRE- ->tr|A0A150QJG6|A0A150QJG6_SORCE Uncharacterized protein OS=Sorangium cellulosum GN=BE15_29465 PE=3 SV=1 --AYSRPAVALDLEQGSTEVLALMLRLIPAPRPRATVIHAFDTPY-RgViypsLSEEDAeewrnelgQTATQqiakliaaslaqakvrpAEAPPWKTHVRCGSARLVIEKAVKKADSDLLVLGTHGYSGVAHVILGTVAGDVLREVACDVLVVPV- ->tr|A0A063Y9C0|A0A063Y9C0_9GAMM Universal stress protein family 3 OS=Nitrincola lacisaponensis GN=ADINL_0001 PE=3 SV=1 --MSIKIILPLDLQdrDSAIAGLVRAKTYLGDRPVEMYFMSILPKPVPllgaylpKEEIASALrvleDEMrllvKQVMpeIGPFFTKATEGVIFKEILKYAREVQPDLIMLPSHSHSKVENILIGSVTSKVVERADCSVLVIR-- ->tr|A0A142HYN0|A0A142HYN0_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PAMC 26640 GN=A0256_22330 PE=3 SV=1 ---MKKILIPTDFSANATHAAEYGYQLAQQLKADVVLCNAVIIPAeapqaglvvwpmeeTTVLLRNSEvelkklkTSMQQHdhsdKFhPAITYIEQAGMLTDVVNDIVKTQHTELVVMATHGSDSLSAFLLGDHCSKMIDNSLKSLLLIPQA ->tr|A0A0R2VIG7|A0A0R2VIG7_9SPHI Uncharacterized protein (Fragment) OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_14065 PE=3 SV=1 ---MLKIIAATDFSPASKHALEFIINATSNLQREIVILNVVHLdgpPPASMissIIEslktKAYFDYQslseeimeKYGeHLPMRFHAEVgGPAHKVIEKVARDENADLIVLGMKGMSDMQK-VfLGSVAASTAMHSKFPIMIVPSG ->tr|A0A1H5ZPW4|A0A1H5ZPW4_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Chryseobacterium humi GN=SAMN05421847_2124 PE=3 SV=1 ---MEKILVTTDFSDHSKSGLRFAIQLAAQNDYLLTFLNVHHLqipSAWDVlseneYQDeqkrIVHAKLIqfveniyeAIHlkPKHVQYAVELsPLPESSVLEFAENHNFNYICISARGAGILNK-ILGTITSNLINQSKVPVIVVPHD ->tr|A0A0J8DC56|A0A0J8DC56_CLOCY Uncharacterized protein OS=Clostridium cylindrosporum DSM 605 GN=CLCY_3c01600 PE=3 SV=1 -MKIKNILIPLDESEKTLESVNTVKSLFNHQEVVIHVVHVVNRYKIAlsepsnphedqlkslNILNKAEKMLS--GY-KVNKITQIAtelSIAMDILKVINENNIDAVFMTKTGKGFFDKYIIGSETSRLLKISPVPVIVTP-- ->tr|E7QMJ4|E7QMJ4_9EURY UspA domain protein OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_00050 PE=4 SV=1 ----MVIVAAIDRTERATDVLAEATILAEKFEEEVHVLHVMKRSEAIQIEEdstnkdeavstaELReqaaQPAKslvdtNPTGVGTTTVGRIGDPASEIVEYADDHQARYVVISPRRRSQTGKLLFGSVAQTVLLNASCPVVSFAD- ->tr|M7NNV2|M7NNV2_9BACT Universal stress protein family protein OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_01422 PE=3 SV=1 --RLRNLLIPVDFTPHADNALRYAIALARSIPMtRLYILHTYHIPAAVtgagamavapYYESElrqsTEEKfqelearmLKNCRV-PYEFVGEYGPAVPDICEASARLEADLIILPAHPTNRLDEYF-GNVTTATIRSSPVPVLVVPPH ->tr|A0A1G1KNE7|A0A1G1KNE7_9BACT Uncharacterized protein OS=Omnitrophica bacterium RIFCSPLOWO2_12_FULL_45_13 GN=A3G36_05740 PE=4 SV=1 -MAVKNIVVSVAGENGGISTVKYAIYLARLLSSKLTAIYVVNERILNEllvrkifveaeahsyardleersrrLLERVREMAHSKGV-ECETILLKGAIHEEIINHTRAMKADMLVMGELKEVLSLKEIFYDEGERIFREAPCPVVVVKN- ->tr|A0A1V6GAQ8|A0A1V6GAQ8_9DELT Universal stress protein family protein OS=Deltaproteobacteria bacterium ADurb.Bin072 GN=BWX71_02265 PE=4 SV=1 ----MKIMMYYDGTDCTKEALPVVMMRAKAFGAEVHVVAslPSGEEKDLKTIDRmnvdldyIQSVFETQQV-PCETHLlITGrGAGEDIGAFARKHEVDEIVIATDRRTMMERLMANWMARRVMSDTRCPVLLT--- ->tr|A0A1W9IU67|A0A1W9IU67_9BACT Uncharacterized protein OS=Nitrospira sp. ST-bin5 GN=BVN29_17950 PE=4 SV=1 --KLRRVLVPVSAEYSPQLAIDTTAQLASALGCdnlTVIVVQVGDDRTLHSL-H----YPIKTGW-LWHTMACQGNVVEVILAMGKDFDVDLIVMTTSKQQTLLDLMRGSTTERVLRGARCPLLALPV- ->tr|A0A167JNZ1|A0A167JNZ1_PHYB8 Uncharacterized protein OS=Phycomyces blakesleeanus (strain ATCC 8743b / DSM 1359 / FGSC 10004 / NBRC 33097 / NRRL 1555) GN=PHY --SSRQIVLSIDPlSEEADYTVQWVAENFLRKTDNIYIFMVLVveDDndvsdeleavvFDDgtlsdiqketaaqnsLAMANIVKRLNAKGFNNVSYRIYkamASKACDTLVQYIDSQKTDCLVMGSRSLSGWKRFFMGSFSDYVQSQAKCPVLIVK-- ->tr|A0A0S7YTU6|A0A0S7YTU6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_04200 PE=3 SV=1 --KPITILCAIDFSKFSKQLIRYATQLAGRLSADLVVFHSVCFPRsaSQdtaasgqvgdgkEGVQRARELIDELmaGqQLPWRSEIRIGEPVVELKALVRELPIDMVLTASYDLSGWKRLLLGTVVEELAQTLSVPMLVVKP- ->tr|A0A150XJK6|A0A150XJK6_9BACT Uncharacterized protein OS=Roseivirga echinicomitans GN=AWN68_04325 PE=3 SV=1 --MYSRILVPIDFTEKSHRALEVACQIAKKLNSEVYMMHIVKAALsvyldelgeyksktptGQQFLDDIlslneekmkrlIQKYEDRGI-TIHSKLKVHDTPNEIAKLVAEEAFDLTVVGNYEHERFDEVFKRTHPEKIAALAKNPVLTINN- ->tr|A0A0C5BVM2|A0A0C5BVM2_9ARCH UspA domain-containing protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1094 PE=4 SV=1 --KIKKILIPYDATPSSEKAVKKIFPLIDKDCSKIIFLTCIHDKATFgffktksdrkEMeqekeknkkyHERLKKEADKLGI-QASSKIIkSDLESKSIIEFAKDQNVDLIVMSKSKIgTHAERLYYNSTVDAVFKKAPCPFLYI--- ->tr|U5C5W6|U5C5W6_9BACT Uncharacterized protein OS=Rhodonellum psychrophilum GCM71 = DSM 17998 GN=P872_02975 PE=3 SV=1 --VPKKVLIPLDFSEHSNLTFKFAQKLFEETNTEILALHIYEVPTGYyktgksyeEfaaIMKgHAKKdyekFLQKYKHQHFECLflMdEKENSGKFITRMAQEHQANWIIMGSRGRTSSASVLLGSVAENLVEaNNMLPMLIFKK- ->tr|A0A150AKP4|A0A150AKP4_9BACT Uncharacterized protein OS=Flammeovirga sp. SJP92 GN=AVL50_12125 PE=3 SV=1 --KEPKALIPINFSETSKDALQQVEEiAGHIHELKSLAINCFRIPNGYsttgksydEmveILTdVSQKkldhFVKSAVDDhniETKPIlIeEDDTTADAIYKAAKDENADVIIIGSKSRTFMASMVLGSTAEKLLLsDINIPILIYKN- ->tr|A0A1E5T1I9|A0A1E5T1I9_9BACT Universal stress protein OS=Fabibacter misakiensis GN=BFP71_17730 PE=4 SV=1 --NTTLLHVPCDFSPHSKIAMEEAIRvARKYKNVKIICQNVFTVPGGYhysgktyeEfaeVMReNAMKdyqkFMSEIDHDgiDLEVVysLdTNDNPVTDIIDFAQKNNPGAIFIGVKGRTSTAALFIGSRAEQLIQyNSDIPMMVVRP- ->tr|A0A1Q5PHB4|A0A1Q5PHB4_9BACT Universal stress protein UspA OS=Pontibacter sp. S10-8 GN=A3841_11375 PE=4 SV=1 --QLRNLVVSTDFSDYSVMAVERVLEiANEKPDIKVVLLHAYQVPTSYrtlgmsykSfdeRMRgFAQAkyekQIQRFPQLqgrAEFALvrLeDEDDIGELVVLEAKRNRADLLVIGAKGMSAAALFVLGSVTEKILRhDLDIPLLVFKK- ->tr|A0A0S2HZP5|A0A0S2HZP5_9BACT Universal stress protein family protein OS=Salinivirga cyanobacteriivorans GN=L21SP5_01849 PE=4 SV=1 --KIEHVMVRMDFTKIAGITMKMAEQlQEL-TGAKISCHHVYKLPLKYfpqnrpedDeklqmHVEkHSKKeyekFAKRLKIDtkAIPCTwtLdVENEEAHILYNQALNIQADMILIGSKIKSEMADVILDTTSEKLAGpEKNIPVFVVKD- ->tr|K2EYN8|K2EYN8_9ZZZZ Universal stress protein UspA-like protein OS=groundwater metagenome GN=ACD_20C00187G0004 PE=4 SV=1 --GTKEVLFAVDGSEFSYHAVKQAISILNLDNSAIEILTVMAGAESLpleitmdnEWLqnslrkqkeiaeeilQNTKKLFQDHNIPVKSTVIQEGDASEKILDYLEENRHDLLIMGSHGREGVSDFLLGSVSKRVLDHSISPVLIIPI- ->tr|R7LWL1|R7LWL1_9FUSO Universal stress protein UspA-like protein OS=Fusobacterium sp. CAG:815 GN=BN791_00576 PE=3 SV=1 --DSKKILFTIDSLDTTPKVVSKCIETMNLSDKDIYLTTVYEVPDYLflegnldsNWIieveqkqekaamlllNQFEKIFIESNLNIKDKVILRGTPAQEIIKYASINEIDLIVSGVRDKKGLSRIFLGSVSKRILENTNSDSLIIRI- ->tr|X1N8A4|X1N8A4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_51924 PE=4 SV=1 --MINKILLPLDCSDVAEEVFPYGEELARKLGCDVILFNACVPEYRLarnmrRlYLKKTaelmQNRLRKYrlkGtGPRVLSEFVHDEFAKGICKYVAANDINLVIMAAHGFTSIRVRPVGSIVDKIFRLLKCPALLVRTD ->tr|A0A090VCV5|A0A090VCV5_9FLAO UspA protein OS=Algibacter lectus GN=JCM19300_276 PE=4 SV=1 ---MKTILYATDCTKNDASALKYAYRFSYIMKADLHVLHVYDFPPIHlsviqpiEklqnrMKQEKKDIVKKfcetHlknefRETPIKIHAVENtSVEDAIIDTAKKLSPDLVILGMKDDHSHRGFFASNIANELLDRVNFPVMMIPNG ->tr|A0A090VXL0|A0A090VXL0_9FLAO Putative universal stress protein UspA OS=Jejuia pallidilutea GN=JCM19301_1083 PE=4 SV=1 ---MKTILYATDCTVNDIASLKYAYRFSTIMKADLHIVHVYEFPPIAnatlhapEllkkrMHIEKTKLVENfckvNlkhefQQKPVTTHVIESgSVSESIQRLSNVLMPDLVIIGMKDHHSTREFFSGNIANALLDTIEMPLLIVPNG ->tr|A0A0U5KCF9|A0A0U5KCF9_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Rhodobacteraceae bacterium HL-91 GN=Ga0058931_0603 PE=4 SV=1 ----MEIMLAYDHSRNARIALDALRDMFGQIKPTITLVSVVEDVGSatsgaddlfNEqyatqkaGVEAAAAELMAEGF-EARVVLAQGDARKMILRATEERKPDLLVMARHShqPDDgplgfiarridalveeFDHMTFGSVSAFLARRAKCPILIIPT- ->tr|A0A1W9LTN3|A0A1W9LTN3_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium IS3 GN=BWK80_53830 PE=4 SV=1 --QEYDVLVAIDQSENALKVAEYVGKMMRShPTVRVTILNIIRPPSPDimpdreerliyvekkrsdvnALINKARGILMSFGIPetQIFTKIqvceEPVSVADQILHEKRECGYGTIVVGKRGMSKKEEFLFGSVSRKIVRECqKSAVWVVV-- ->tr|Q0W0J6|Q0W0J6_METAR Predicted universal stress protein A OS=Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50) GN=uspA-8 PE=4 SV=1 --KYGRILIPISGYKHALRAIKMAELLAKKYGSEITVMYVGTEKDdPRQVITPVTSDLKGNGL-KHRAIFRTGPVVETILAEAE-KNYDLIAIGATERQQPYNFVTGSTADRLIKKSSCPVLMIKT- ->tr|S7VU52|S7VU52_9FLAO Putative universal stress protein UspA OS=Winogradskyella psychrotolerans RS-3 GN=ADIWIN_2210 PE=3 SV=1 --IMKKILLLTDFSKNATNAIRYAMQFFESEKCTFYILYVHKISGYVsddllmspkdsihdSITKKPKeklnaliEKLKNEtktNDYQFEILIDFDVFTDAINQVVKKFSIDFVIMGSNGVSNVKEVVFGSNTINVIEKVNCKTIVIPSN ->tr|M7NCY6|M7NCY6_9FLAO Uncharacterized protein OS=Xanthomarina gelatinilytica GN=D778_02238 PE=3 SV=1 --HMKHILLLTDFSESAKNATNYALQLFQDQASCFYMLHIPQKSVYTtsdlmaagtssiynSLVKKAKtkldkyvKTLESNssnKKISFETIVDYDVLTDSVNQIISSKKIDLIVMGTNGVTGAKEVVFGSNTINVIRKVDCATLVIPKG ->tr|A0A1E2Z1P1|A0A1E2Z1P1_9GAMM Universal stress protein UspA OS=Serratia sp. ISTD04 GN=BBC05_08500 PE=4 SV=1 --MIKRVLLAVDCFEHSGNALDFMARLQG-SIGDVIVLTVVDNAFTLsrsglrfdseEreeypaaqreealaekQVGQVTRALKQQGF-NAQGLLAAGTPIEVIPEQMALFNCDLLIISHRHLSSLGRWLNASVTRGLLDEIGQPVLVIPR- ->tr|A0A1Z8M0K9|A0A1Z8M0K9_9FLAO Universal stress protein UspA OS=Muricauda sp. TMED12 GN=CBB72_09850 PE=4 SV=1 --SLKKILIPFDFSEASINALEYVVNFIGTERsIGILGLYVGNMpiseTDNEKLEKDFSKVMDSfdvKLKIAPEFTTDTGEVIGTILSAQEKSNADLIMMGTMGDKI--TDEAITNTSKLVLKANCPVISVPY- ->tr|B4U9B0|B4U9B0_HYDS0 UspA domain protein OS=Hydrogenobaculum sp. (strain Y04AAS1) GN=HY04AAS1_1035 PE=4 SV=1 ----MKYLVSVDFSDITNLVVRSAKVFATKLNVELELLHIIAPFTYlpyPeglsidivdmDIIKKaeenaknlALEKLSALaeylDPVKTTYKVLIDTPFAEIVSQEA-EnnNMDGIFLGGHSKNLIEKILVGSTTEDVVKNSKVSLVVIKA- ->tr|U1PUH0|U1PUH0_9EURY Universal stress protein UspA related nucleotide-binding protein OS=Haloquadratum walsbyi J07HQW2 GN=J07HQW2_02488 PE=4 SV=1 -HMFETILIATDGSESVRRAVDTGLDMASRFDATVHCLYVIDESDVNtdtqkpgsdhdhdhpAMYehgQEAVETVAERTDGEIITTIERGDPPSVIEAYAGDIDADVIAMGTRGRHGENRFLIGSVAEELVRTVEIPVLTVRQ- ->tr|A0A0U4W0T7|A0A0U4W0T7_9BACT Uncharacterized protein OS=Caldimicrobium thiodismutans GN=THC_0367 PE=4 SV=1 --GYRKILIIYRNSPE---FLRESFKLAKKEGTWVVVLKPLPTYEGElhltgiknleEILEgyklkeykQIKELTEEERV-LAKIRVEEIEKEEDILDIAIEENCDLIVIEPKKPTLFERLlsLKDRLIELLIDQSPCPVFIIR-- ->tr|F4B076|F4B076_DOKS4 Uncharacterized protein OS=Dokdonia sp. (strain 4H-3-7-5) GN=Krodi_2351 PE=3 SV=1 ---MKHILIPVDFSDQSWNTALCAFNLHKSAGVRFYIFFSEQHDYATgeatvicehpaQQLSSWVKKLEKlkGSGQVIIPLKWESDFISDMRGAVADNNIDLIVMSTHYPNIFCDVLKGSHVREVITRLKCPVLIVPR- ->tr|A0A090PKP0|A0A090PKP0_9FLAO Universal stress protein OS=Nonlabens ulvanivorans GN=JCM19297_807 PE=4 SV=1 ---MKHILIPVDHSDPSWAAVHCAISMHRDAGICFYLLHRESLNLQLdeevvklktdyNTLQARIESTKKllSPHQKLISLSSDGTFIAQVKEAVYENDIDLIVCSDLYPFDQKAKVDLTYTKAIITRVKCPVLIVPQ- ->tr|A0A136JRC0|A0A136JRC0_9BACT Putative universal stress protein OS=Nitrospira sp. OLB3 GN=UZ03_NOB001003104 PE=3 SV=1 ----MRWLVALDESEFSERIIGWMRAFPHSKQTAVTVVHVLAPLDVPEtigltgqqlllqqqgamveaLLQRVRRLLE-ESFADVEVILREGVPSREILQVIQERRPDLVVSGMQGLYRSPGFTIGGVAQRLLSYAPCSLMLVPG- ->tr|A0A0Q5WA42|A0A0Q5WA42_9ACTN Uncharacterized protein OS=Modestobacter sp. Leaf380 GN=ASG41_14210 PE=3 SV=1 ---PAPVVIAVNDRPEGSAALTWGLKRARRLQTTAVLVPSTGDTpsaPVHLsvaTRDLIESATAAAGV-DYVLHEQPEDVAQALITLS--EGADMVVLPVRRRSVTMKFLLGSNAMRVIAEAHCPVVTVK-- ->tr|A0A1N4YLG8|A0A1N4YLG8_9MYCO Universal stress protein UspA-like protein OS=Mycobacterium abscessus subsp. abscessus GN=SAMEA2071243_04046 PE=3 SV=1 ---EKTVVLGLR-EDASENVIAEAVREAKLRQAALRVVMFSADDpssPNYSgvsQVKEIARELIDAGV-EFEIFRPASDVGEQVLELARQHNAELIVLSIRKRSPMLKMLLGSATQHVLLGADCPVLSLR-- ->tr|A0A1V4RTG7|A0A1V4RTG7_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4484_190.1 GN=B1H11_10170 PE=3 SV=1 --LTKRITIPLDGSQNALRSLDYLNFIYGPKhNLEIILIYILPQLPSFmtdktsfdketwirirgveeksiqmaeRILEQAKNVLIEKGFPeeRIKAQYkkQETGVASAICNMAKMKQIDTLLITRRGRSNIKTFFMGGVSKQLLDSCqVCPVWIVGS- ->tr|A0A1V4RTG3|A0A1V4RTG3_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4484_190.1 GN=B1H11_10165 PE=3 SV=1 --AGNKILIAVDGSDQSLYAVRYVSKMMAPKKTEIVLYHSIRKISEAfwemgvkpissqklssiraweisqekkihEFLSLSRQIFLDNGFPeeSVKINIheTRKGIARDVYNESK-SGYTGVVAGRMGLNVLKDLVLGSVAAKLVEKLhDTPVCLVGG- ->tr|M0LXI4|M0LXI4_9EURY UspA domain-containing protein OS=Halobiforma lacisalsi AJ5 GN=C445_00535 PE=4 SV=1 --TVDTVLAPVDGSDESATAVEYAVAVADRYDADVHALFVLGRGVVRgldagtvdeddvaektqGFFNDIGSIADDYGValstsvdDGFSQTRKTRHPGNVVLDTADELDADFIVLPREPVTEPSAEVLEKAAEYVLSYASQPVLSV--- ->tr|B1X544|B1X544_PAUCH Uncharacterized protein OS=Paulinella chromatophora GN=PCC_0638 PE=4 SV=1 --MFKNLLIADSDKGHVEDMVRMLRDIPQLSQANLNFLYVVTEQAGEGveeNWKkvadsveVMTKRLGMS-PSEVNVIIRQGDKKQTVLKVADELDVDLIVMSSRGLGRLQSILSNSASQYVFQLSTRPMLLVRED ->tr|A0A1X0UKS6|A0A1X0UKS6_9NOCA Universal stress protein UspA OS=Rhodococcus sp. 1163 GN=BJD99_04455 PE=4 SV=1 ---TAELVVGWDGRPPSTSAVEYAVDLAERITAHLHVVHIVDIDDlpidpdssdYETELRatldeqarHARELLDGLDA-SWTYHAWHGSPADLLDTVADEYKALMVIIGSPRGgfmSFLDSIGGVSVSHRLISRHRHPLLLVPE- ->tr|A0A0P7XIR2|A0A0P7XIR2_9BACT CPA2 family monovalent cation:protein antiporter OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_03730 PE=3 SV=1 --QPKRVLVPTNGSKAARNAAEMAFMVGRAlENCEVIAMNVSSNERARlgielqDnRDfdrkkiaHEIVAELKKSGEafgVSTEALVVHGEsPEQAITLVAEENNIDLIMVGTSVRPASSRLYMGPRVENIIQHARCPVVIFNA- ->tr|A0A0S8DAQ4|A0A0S8DAQ4_9BACT Universal stress protein OS=Nitrospira bacterium SG8_35_1 GN=AMK70_10760 PE=4 SV=1 --DIKRILVVSRSTIDCRKAVHYGVSLSWKYTAELYVMHVVHDPLIfgkwnlpfpsieeeyRNMLKKAKSELNeiitkekSKGL-TIKELIKEGKPSEVVLNAVKEENIDLIIMITHEEGLLEHFIFGRSNKEIVRALPCSILLVRK- ->tr|A0A151ZFX4|A0A151ZFX4_9MYCE Uncharacterized protein OS=Dictyostelium lacteum GN=DLAC_05412 PE=4 SV=1 ----MKYLVCVDGSAEARKALSKAITMVST-EDSMYFLNVYPPLPSEngicpssnctltkmviEmfsgvpdLvdeddpIKQQKKsnkkkslalkefnFIKSQQINekcNVHYlLVASPDISDTITKIAEHYCVDAIVMGCRGLGL-QKLLIGSISSQVLQMSNCSVLIVR-- ->tr|F3Z023|F3Z023_DESAF UspA domain-containing protein OS=Desulfovibrio africanus str. Walvis Bay GN=Desaf_3776 PE=4 SV=1 -GMFTRILVALKYNDTGRHALSVAAELARIHGAELIAFHALDYRLlaegvSaaerDQACDAAHRRFEQeFGpifreGGASDFVCLPADPAMAVCRLAREREADLIVLGCHQRGQGSgLSRMDYTGMTIMDKAPCPVLLVPY- ->tr|A0A1B6Y6S8|A0A1B6Y6S8_9BACT Uncharacterized protein OS=Balneola sp. EhC07 GN=A8B79_11195 PE=3 SV=1 --KVNRILIPTDFSEQSKSALKLAGFFTKIYGSTIDLIHIVPFSMYmsesmdklglpfdmdkdlyPKVVEKAKSELDELASdfimekYLGKTHVQVdRKPSSAIAEFANKEGYDLILMSAKGAHE-TNFFKGSITDKVIRKAHAPVFTVSR- ->tr|A0A0S8K5M6|A0A0S8K5M6_9BACE Uncharacterized protein OS=Bacteroides sp. SM23_62 GN=AMS26_01970 PE=3 SV=1 ---LKKILLPVNPEYYTRETLDFTIQLAKLYQSEIIPIHIIGKEAEFmsirdiahkiaeEHIKKVQSRIKKEGINTVDPVIDFGNHFDRIAIAALKYDVNVILFGIRIGTEQEGSSLNLNIEKVIRHCDKPVWAVKE- ->tr|A0A0S8A2Z2|A0A0S8A2Z2_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_17 GN=AMS18_05200 PE=3 SV=1 ---LETILLTTDFGKGSAPAMDAAVALAQTFESKLVLLHVIAESLLPflsdqgdiaeieKRLHEVAKQIEAQGVGAPEIFLGKGVPAEVICGEAARRDANLIVIGCGARERGGKCRPGVTADRLLRRAITPVWIARM- ->tr|W5H054|W5H054_WHEAT Uncharacterized protein OS=Triticum aestivum PE=4 SV=1 ---GRDLLVAIDFGPNSRHAFRWALAHLARIADTLHLVHAVSSVHNelvYNKSQELMDELAVeaFKEslVHTKARIVEGDAGNVICREAERLKPAAVIIGTRGRSLIQSVLQGSVSEYCFHNCKAAPVIIVP- ->tr|S0G776|S0G776_9DELT UspA-like protein OS=Desulfotignum phosphitoxidans DSM 13687 GN=Dpo_2c03320 PE=4 SV=1 --MFNKILVPVDIDYPkaSKAVYDNAAELASLSGAQIRIVSVMPGFTMpivasfvtEEIKKQAQAHFQkalddfvAAncKGANVSYKVLVGKHYEEILKMADKWGSDLIVVYHNRNRTVNEAFSSTCAQRVVKEANCSVLRLRN- ->tr|A0A0S7BM31|A0A0S7BM31_9CHLR Universal stress protein family OS=Flexilinea flocculi GN=ATC1_131391 PE=4 SV=1 --EIKQVVLAFSQSPKAREAMCFADILSKSTNCKISVVISGKDETRrNSAYEEVKKYYIRQNV-EADYFVIDNEPEVAILQTADQIHADLIVMGGFSRSLLQRIFKRSTIDKIFVATKKPVIICK-- ->tr|A0A0C7CIR0|A0A0C7CIR0_9FUNG Uncharacterized protein OS=Rhizopus microsporus GN=RMATCC62417_17281 PE=4 SV=1 --ESRIVAIAYDYSNYGDAMIAKSIHSDLlRPNDDIRILYVMNQNDYHNlftpmltvygtnrnyddsqdaylrnavdtFMWEIITVLNKRGFHNVSSEILRGDPKEVIVDYCRAVKPVYLLTGTRGLGAVKRICFELLSKALPLSCASD------- ->tr|A0A0C9MT24|A0A0C9MT24_9FUNG Uncharacterized protein OS=Mucor ambiguus GN=MAM1_0127c06026 PE=4 SV=1 --KRRVVVVAYDHSNYGDAMISKSIRLGLiRPRDDIRLLHIVSQSDYRNlfapmlsatgtsggvhasdldsnmasvadaMIYEVINSLRKIGFSHIKSEILRGDPKESITDYCRMSKPAYLLTGSRGLGAVKRTVMGSVSSYLTKHCPCPVLICKL- ->tr|A0A015IKS6|A0A015IKS6_9GLOM Uncharacterized protein OS=Rhizophagus irregularis DAOM 197198w GN=RirG_231490 PE=4 SV=1 --KNYNILVAVEETSISNNAIEYAFDLCSRLKdsYSLSIIYVIAlnPEtnvPFLhnldkannlDILLDAkeavnkiREYLKKFdntyPNVQYDliEHKGYGVVGKILTEYISQNQLDlnLLIVGSRNLDGLQKVVLSSTSDYLARHVHCPVTIVKQ- ->tr|D4W223|D4W223_9FIRM Universal stress family protein OS=Turicibacter sanguinis PC909 GN=CUW_0860 PE=3 SV=1 --MYRNILVAVDDSEKSKLALNSAIHsavvFNSKLTichIKKNTIIYTPidPTgmlstTHIfkqdfsnymDEELEKykemalNQGVKEV------eiVQTYSSSPGLAIAEVIAP-GYEvdLIVCGASNKSGFDRFLLGSVSFDIVKHAKCDVNIIRN- ->tr|A0A1Y1Z5U5|A0A1Y1Z5U5_9FUNG Adenine nucleotide alpha hydrolases-like protein OS=Basidiobolus meristosporus CBS 931.73 GN=K493DRAFT_404268 PE=4 SV=1 --IPYTLVVALDSGELSRKTANYAIDLVTRLAcpYKLYFIHAIGlnPAqslPFLddldkannyDIEEKGervvaenLKWLEQ-ykNKVQYEwvTLKEAGECGVIIEKYINS-LPHvdIVITGTRNYEGVKKFIMGSLSEYLVHHIKYPVVVIKS- ->tr|A0A1F4RRL1|A0A1F4RRL1_9BACT Uncharacterized protein OS=candidate division KSB1 bacterium RBG_16_48_16 GN=A2V82_10390 PE=4 SV=1 --FFKRAVVAAAFSPRLVAVLNESQRILKILGAWPIIVHIGEENPS--NRSKLEDAVARSEFrdhPP-VLIVRAGQPSDVLMDVVLEYEADLIIAGALKKERLFKYYLGSIARNLARYSRCSVLLL--- ->tr|A0A0W1RE19|A0A0W1RE19_9EURY Universal stress protein OS=Haloferax sp. SB3 GN=AUR65_05020 PE=4 SV=1 --TYRRIALLASDAPSSEPTATLARRIAAATRGTLEPLAVVDERDAAiaspetrRALeREARTRVKDvvaaaarDAV-ESGGTVRTGVPTAELLAHVERTGADAVVLGVGGNGrsgrsggdggsdgsdengesgdaprPSEHRATEVVANRTVRHAAVPTLVVPTP ->tr|A0A139GSJ5|A0A139GSJ5_MICAE Universal stress protein UspA OS=Microcystis aeruginosa NIES-88 GN=OA58_06605 PE=3 SV=1 --KIKKVMVALDKSSSADLALDLAIYLLRDyPSAELILARVNPDLKpefaptspkemeENPILRPAVAKVKRMNI-PYRCLVTGGKPGEQLCKLVDDYNVDLLLLGSPDRRPsvakslpdLDRLLGTSLSDYVRVNVNCPVLLARK- ->tr|Z9JS94|Z9JS94_9MICO Universal stress protein OS=Brachybacterium phenoliresistens GN=BF93_17865 PE=4 SV=1 ----MAVVVGFIPTPVGFAALEAAQREAERRGGPLIIVNVVRDGMQgdprhadQGQLERAQDMVRRASVRiAVRQEHTDDDISDVLLQVVEEEKAELLVLGIRRERDMASHLLGVTVQKLLTSSPSDVLVV--- ->tr|Q55FP9|Q55FP9_DICDI Uncharacterized protein OS=Dictyostelium discoideum GN=DDB0189712 PE=4 SV=1 ----NRYMICLDGSQVSERAFHWLEALAMCDLThqtEIFLFHAVDRKAVtkleldtnpnctrhelaEKALDEYTKSLAVNNVI-SHKLLIdtKESVKDVIIKEIEKNKIDMVVLGHEDKGRIERLLDGrgSVCEYLLKNVDIPITIFK-- ->tr|A0A1M5M3K1|A0A1M5M3K1_9FLAO Universal stress protein family protein OS=Salegentibacter echinorum GN=SAMN05444483_1243 PE=4 SV=1 --MEKKVLVPTNFSKHAWNALVYGLNLYRDIPCTFFILNTYEASNRLsfpktkkGESEDAKLesekglqkilqGLNfrKeNLQHKFEVISSKKDLTKAIQETVDQHNIDLVLMAAHGAKVSINTAFENEISEVTDVIQnCSFLILPE- ->tr|W8T8A6|W8T8A6_EUBAC Uncharacterized protein OS=Peptoclostridium acidaminophilum DSM 3953 GN=EAL2_c18130 PE=4 SV=1 --MIQSILLPVEGIEFSKRAYKIALDIAQKYGAFVTILHIDKRPAYapvepvkakpPkkgnvsEfkhaarskgkndIANSAKAYFGAHGI-KVQVIVTYSDTVQAILEHAASGKYDVVIMCNYEDSLIKKFATSFTIKRIIAKSQIPVLVVQA- ->tr|Q7MSX9|Q7MSX9_WOLSU Uncharacterized protein OS=Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W) GN=WS0007 P -SSKFPLLVATDLSPTGKVVLEKAFKLAKRYHKPLFILHVSETTLFAPkiieltQIEANLCKlLEPFyaRypEVKATLLCRQGGIEESIISAIKETQASLLLIGTSGEDnLLREFFLGSHCRKIIRSSTIPVLVVKN- ->tr|W6EUE6|W6EUE6_SULMU USP-like domain-containing protein OS=Sulfurospirillum multivorans DSM 12446 GN=SMUL_2828 PE=4 SV=1 -MEKLTMLVATDFAESSAAVLKKAIDFAQKTQATLHVVHVVENTFFQKnqnidfIKEHCWDSMLSHyPsLHKEHFYCFEGNVETVVAIVAQTIGAKIVLIGDNRDKhPLEAIFISSDTKAIIRESHTPVLVAKN- ->tr|A0A193LDE9|A0A193LDE9_9GAMM Uncharacterized protein OS=Woeseia oceani GN=BA177_04385 PE=4 SV=1 --DQGCILAAIGMPDRgplltelDSYILAKAAAIALAEFRELHVVHAWQLSHEghmRsfgtKaanlevdrMIAReaalrtnglrrAIEATTSEsAriatdFLAPHLHIIKGHTENVVPELADRLGAGLIVMGTAARTGLSGLWIGNTAEKVLSRSDRSFLIVKAP ->tr|A0A0S4I322|A0A0S4I322_9PSED Universal stress protein E OS=Pseudomonas sp. URMO17WK12:I11 GN=uspE_5 PE=4 SV=1 ---PRKIVAAVDPFHRngqyksfNDRILQEAQKLASTCHAELDVIYAHDLSSISadefgfangstffssSKAKmlfdaqaDAFRElSERNGIPPERQHLIMGNPVKVLASYAAAYETDVIVMGRIGHRTMDR-FIGSTVEQLLFKMPCSIWVI--- ->tr|A0A1C7ZAP5|A0A1C7ZAP5_PSESX Universal stress protein OS=Pseudomonas syringae GN=AFK24_06080 PE=4 SV=1 ---PRRILAAVDPFHRdgryqdfNDRILHEAVKLATACDARVDVLYAHDLSSISsaefgfddgsaffssKVAKtlfeaqgEAFNElADRNSIPPEQRHMIMGAPANVLSAYASAHDIDVVVMGRVGHRKPGR-LVGSTVESLLYKVPCSIWVI--- ->tr|A0A1J5DLV9|A0A1J5DLV9_9DELT Iron/manganese transporter OS=Deltaproteobacteria bacterium CG2_30_66_27 GN=AUK27_01645 PE=4 SV=1 --PFRKIAAALDFGEADAEVLSRAAGLATANRCPLLLVHCVESAGAaamggeitdteskkdLERLQRYTLVLGKHDI-QAEAELGFGDPVRVLPEIVRRHGVELIVVGAHGHKGLSDWLHGSTIDELRHRLNISVLVAGR- ->tr|K8EZM2|K8EZM2_9CHLO Uncharacterized protein OS=Bathycoccus prasinos GN=Bathy02g01870 PE=4 SV=1 --SRRRRVLlPVDITSSSEEMCAWACENFFRPSDIVTVLSVAKKQIVPhgssyfglshdhseaEAVLHAQEWIethikprlEKCGC-GVEVIvklleTDKHHVAEAIIEESKRvdenensrYKFEAIVLASHKRGAIKEFFLGSVANYVLHHANIAVVVQRM- ->tr|I0Z066|I0Z066_COCSC Uncharacterized protein OS=Coccomyxa subellipsoidea (strain C-169) GN=COCSUDRAFT_62559 PE=4 SV=1 --------MgtPGDCTHDAEDAADWAAVNLFKPGDEFHLVHVIKDESEQlrefyqekSLEVAANRFIqerfvpklVAAGI-IVVVDivrkpSDEAHPASAIVKKADEIDAACIVCVPHEHEFVEAAFHTSIAKWIVLNSKRAVTVLHP- ->tr|A3ZQS7|A3ZQS7_9PLAN Uncharacterized protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_20637 PE=4 SV=1 ---QDVVVITYDGSIPSSHALHMWTLLKLRRpETQVHVVSVDRDLAIaQKHCEEAAVLLQYHQVQATlHPVQLTSKVVTHLSETIAEIAPRTVVMGAYGSGGFREALFGSSTNRMLENSESLLFLY--- ->tr|A0A1G0CM58|A0A1G0CM58_9FLAO Uncharacterized protein OS=Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24 GN=A3E30_02200 PE=3 SV=1 ---HNLYIVPHDLTPVGDTALEYALFLGNHVRTEVMVLNLVDNKAKiAPTQQKLEAIVASKqipASVNVTVNVALGDIFTDISKIANKEHAQLIIMGTHGAKGFQ-KLTGSYAMKVITSCDVPFMIVQD- ->tr|A0A183R8G3|A0A183R8G3_9TREM Uncharacterized protein OS=Schistosoma rodhaini PE=4 SV=1 ---LRKVLIPLDNSNESKKALNWYKENMKRDGDLVIFVHVIDPILPsalsalshecesmpagssfhvpEESMKSAKILCQemvneatKYGIKS-EAVIqIDNKAGPALVKTINERKINVVVMSKRGLGFWKLNFTPSWHILSD--SRLNSRMHQP- ->tr|A0A0R3SUQ1|A0A0R3SUQ1_HYMDI Uncharacterized protein OS=Hymenolepis diminuta PE=4 SV=1 ---DRVFLFPVDDKRTTQRAFLWFINTFVQSRDEVVVLHVIKPIDDvveelgysvfssypaptrglvmDNRVAEARKICStylefahSRGLTGIRGSIsTHEKVEEAIVKSAMVNKATTIVMPTRGLGRWRLFWGNSVSGFVSKHSTIPLIIIPP- ->tr|A0A202DW36|A0A202DW36_9BACT Uncharacterized protein OS=bacterium J17 GN=BVY02_01060 PE=4 SV=1 ----SSLVIGYDGSAASERVIRLAANIAEAMDLgTVHLLTIDSDLErAEKVQAPGLDYLSAYDF-DLVPVCLDGEAAEEIISYAKEVDASIVALGAFGTNRFIEKVFGSTTQTVLDGAPSAVLLVS-- ->tr|A0A0J1FNY3|A0A0J1FNY3_9FIRM Universal stress protein family protein OS=Desulfosporosinus acididurans GN=DEAC_c27610 PE=3 SV=1 ---NFNVLLYSDGSRQSISAAVYAASLINNiPNMKLTILQIHESHERfmgsefswielrrkykriyweseselswsqtylkipdDDWFKrmlnseedcgdqyarivsKTNRIFVESSH-SIKHQILysninksdISDTADLILNYSSRNSFNLIIIGLQGFSMFNGLIFGGLAHKVQNKSSIPVLLIK-- ->tr|F2ICK3|F2ICK3_FLUTR UspA domain-containing protein OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_3502 PE=3 SV=1 ---RNLYIVPHDLTEVGNTALDYALFLGRHVRTDIMLLNLVDNKAKIaGVEAKLWDIIkakVIPESVEMFVLVAVGDIFTDISKIANREHAQLILMGTHGAKGFQK-LTGSFAMKVITSCDVPFIIVQK- ->tr|A0A1Q9GFD6|A0A1Q9GFD6_9GAMM Universal stress protein UspA OS=Photobacterium sp. 13-12 GN=BIT28_25240 PE=4 SV=1 --MFSKIMVPVDLRHEeqLTKSLDVVAKLAKVYGSKVVFVGVSLAAPTeisrnpeeyKAKLALfTQEQSDLHNIDaESHP-IFSVDptadLNKKLLDAIDEIGADLILMATHIPN-VSDYIFANHGNYISDHADISVFLVRG- ->tr|A0A0U2XLX3|A0A0U2XLX3_9BURK Uncharacterized protein OS=Pandoraea norimbergensis GN=AT302_16845 PE=4 SV=1 ---PLDILVPVSGTDYSRHAAELAITLARATNAPVTALHVSARMApgmmhkrwrprSLRpdaaeaaMLENLQALAERNGV-TLRTRLLAGgKVDEAVLHQIHHGKHNLLVLGVQPRF-GDRLNFGAISHRLLEERRCSVIVLSA- ->tr|A0A0J1GWN9|A0A0J1GWN9_9GAMM Universal stress protein family 1 OS=Photobacterium aquae GN=ABT56_16125 PE=4 SV=1 --PVKQVVAAIDLANQdyqefNAKIVDLAVEFCSVTGAELTLVHAWRLESegFlrkwsgYEdldiallsqqMRSERLERLKSllipYenSPIVKHIKLLEGETREVLPRYVATSDTDLVILGSLSRTGIAGFLMGNTAESMLNTMSCSVITLKPD ->tr|A0A177QC71|A0A177QC71_9BACT Uncharacterized protein OS=Nitrospira sp. SCGC AG-212-E16 GN=AYO43_08365 PE=3 SV=1 --SFRKIFHPTDFSAGDAAAFAHAVKLACLVQGELTMMHVDPAIERkdFEDFPRIRPLlvrwgvlqegcskddVAKLGVQIKRVRAVADNTTGALLQQLTAHPTELLVLSTHQREGLARLTHHAVAEPLARGTHARTLFVPAG ->tr|M5SZ63|M5SZ63_9PLAN Universal stress protein OS=Rhodopirellula sp. SWK7 GN=RRSWK_05272 PE=3 SV=1 --LARFILHPTDFSTESSVALAHAVHIAVNNKATLELLHVETDPaaneddqddvPDedWNQFPSIRTMletwglipsgdarsdVTDLGIEISEVVSYGADVPEVIAEYCQRRPIDMVVLSTSGRDGFASLLMPSTAERVANKMSnllIPTLFVPKH ->tr|A0A1Y1QIR7|A0A1Y1QIR7_9GAMM Uncharacterized protein OS=Thiothrix lacustris GN=BWK73_31120 PE=3 SV=1 --QFRTLFHPTDLSAASEVAFVHALKLAVMNKSSLTLLHVAGKHAHvhSNHFPSVRETlegwgeipphsdkaaVFALGVTIHKVVSKPEDPVRACQRYLESHSIDLVILAVHQHNSRMGWLHASIGQPIVRNSGETALMLPHG ->tr|A0A133VL21|A0A133VL21_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382A20 GN=AKJ51_01975 PE=4 SV=1 --MLEKVLAPIDSIKwdNTKTAVESVMKIGRSYRvngsPELNFLHVFHAKPKIPMaerdritdLkkreikedfETIKEMCKENGLENVRTVTRTGKPAKEIVKYAEEKNVDVIVMGSGKlhdrttTGKIHKFFYGSVTERVIHEAPCSILVAKPG ->tr|V4C3I4|V4C3I4_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_231833 PE=4 SV=1 --KTSTVLLAVDNSSNAEYCMNFYLQRLHKQGNKLVILHVPEYWGDmarmmsparlTEVYNesqkrakVIGEKFHtiaaKNSVSDIEFvTKDGNDPWHVIVDVAKDKKVDFIVMGSRGMDFLTRASIGSVQANQIAPFEVGCLFQ--- ->tr|M5RSV9|M5RSV9_9PLAN Universal stress protein OS=Rhodopirellula maiorica SM1 GN=RMSM_00711 PE=3 SV=1 --DPMKITIGYNDCEGSAEAICEFTKLDWDTTAAISLLGVVPVFQGFspdlmpnivqyrseqrvAAmryLQSGRERLVSehsqLSTDQISCDvVDTDHVGNAIIERLEEEKSDLIVIGDSHRSRISRMILGSVSRFVLHHAHCSMWIARD- ->tr|I2K7U4|I2K7U4_9PROT UspA domain-containing protein OS=Sulfurovum sp. AR GN=SULAR_03582 PE=3 SV=1 --ELKRILVGLDVTEKSNNVLKRALSVANEHKADLFIVHAVQTPWLGVPsyfggkdvvidhqsiAQKIEKKikpLNREFKVNCFVFVKEGNPQDVILYESKLNQIDMIIIGAHSKAKGKKGFLGTTAQKVAHLSHLPVLIVKN- ->tr|G0HR54|G0HR54_HALHT Universal stress protein OS=Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-17 -----TILVAIANDSVSPAVIDTAVRLADGLDEELYVVHLVDEDTadgtAMQLRDEMRERFRDATIVatvAIEhvgrSAMRSGTrIGNELLELAADVDVRHIVMGHEPKGLAGRLREGDAAVAVIDAADVPVTIVPE- ->tr|A0A0S8KP93|A0A0S8KP93_9BACE Uncharacterized protein OS=Bacteroides sp. SM1_62 GN=AMS23_06320 PE=3 SV=1 --KNRQILVPLDLSKAIQSKISKAIEFAGILHSDVSVLTILRSDGSnleaqyRRRLDEIREIFNNAGV-TCKVKLVKSkhPVPQEILSF-AkSTRVDLILIMTQQETHYTDRFVGSAAQEIINQSEFPVLSIRP- ->tr|A0A0R2VHU5|A0A0R2VHU5_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_11340 PE=3 SV=1 --QFKNLLLPIDLSRHTNEKVERILRFAQEFHCHIHLLAVSEFLeeLTfskkelLERLEASAQYFKAAGL-RCSTEIIRHdLVSHSVVAYATEIKADALVVMAEHKSIITSMLLGDRTNKVVATSPIPVISFRP- ->tr|A0A0S2I4Z2|A0A0S2I4Z2_9BACT Universal stress protein F OS=Salinivirga cyanobacteriivorans GN=L21SP5_03721 PE=3 SV=1 --NLDKIILPLDLTKETREKVTDAVHLAKRFHSKIYAVSFSSTRDDgvvghlKGQLRQVSDFVEKAGI-EIETDFRFYdgNRRKKFLEYVQDKDADLVIITTHQQPEIVRFFMGSFAKEVVHSAPVPVLSIVP- ->tr|K0NDJ0|K0NDJ0_DESTT Uncharacterized response regulator receiver domain protein combined with universal stress protein domain OS=Desulfobacula toluo ----MKILVGYNGGEVGRLALSLARDYALKNNAFVYIITSMQGGTSEKqsDILKAEenlefaKKLMEhSKVkYDAQQSVRGLSPGEDLVKFAQENDIDHIFLGIKKTSRTQKAFLGSTSRHVILKAPCPVTTVKF- ->tr|Q0AC76|Q0AC76_ALKEH UspA domain protein OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_0206 PE=3 SV=1 ---VALVILPVDGSPACVAAAGHAGLLAQVLHARLQLVHVMPPIPAEfsdlpanrkpetdqdraEQLENArqafekaRAILDPSLEPEClTLEPddesLVHRPGRVVADHVRRQSDCLLVLGARHMSDLVKLVEGSVSNEILHRVQCPVTVVHD- ->tr|A0A179EJU5|A0A179EJU5_9EURY UspA domain-containing protein OS=Haloterrigena sp. H13 GN=HTG_09925 PE=4 SV=1 --DPAHVLVPTLGRPREDEALAYACETF--PDAEITLLAVVTPLDAplseggvlerdDERTAAARESatelLASVddptATERVRIETAEGRPGTVVPRYASDEGVDHVVLCGSg-SgsVGFFRRFLGrGIAATVVERTAEPVTVLE-- ->tr|K9YJJ2|K9YJJ2_CYASC UspA domain-containing protein OS=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) GN=Cyast_0598 PE=4 SV=1 --MLQRCLICTDLKDGLHKLTRFVASFEHSGLKEITFLHSVPVWTegeipriDYERIEEVKNFLSSQlenvpDTIKVNIEVISGDATPNIIETVEKYNIDFVILGTAVRTAIQEGLFGSTATKLTKKLKVPLMILRP- ->tr|A0A152A6F1|A0A152A6F1_9MYCE Uncharacterized protein OS=Dictyostelium lacteum GN=DLAC_01821 PE=4 SV=1 ---MVNFMIAVE-SSDIEHTLNEVVSHIFnKQNDHLFFITIVEDItnfpssPMStvfiaDSMKiierKHKDilieccnKAQGLGLSNIKALLGHGSnAGDHICKAAKEKQIDYLVVGRRSMGSIKRIFMGSTSKYILEHAPCNVICIKD- ->tr|Q556D4|Q556D4_DICDI Uncharacterized protein OS=Dictyostelium discoideum GN=DDB0203317 PE=4 SV=1 ---MVNYMIAVDEGSNTEHSIKEIINHVFqKDKDLLYLISVAEDPitfpssAISavvvsETLKaierKHKSilinranLCKNLGVQNVKALLGHGNhVGEAVIKAAVEKDIHYLVVGRRGIGPIKRIFIGSTSRYILEHAKCNVICIKD- ->tr|A0A0H3ADA2|A0A0H3ADA2_DESVV Uncharacterized protein OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4) GN=Dvul_2842 PE=4 SV=1 ---MRRILLGSDGSVEARHAEDHVIATLRREGGSVMALHVVDTDLMhyglvdqlatqsdketfLnyvreqgeseceARLGGFVERARKSGV-HALLGVRWGEPLREVLAAATENGADEIVLPPHSW--GMDFTTPHLAERLNRSSPCKITIM--- ->tr|A0A1F9KDG4|A0A1F9KDG4_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_12_FULL_60_19 GN=A3F90_01050 PE=4 SV=1 --NIRRVVFASDFSPESRKAFRRFCETFAPMNAEIFLYHAVPRPPKwtiqsgTNLFvgdatksrqeklsmrkKLARPFLeeaTAAKA-RVEISVeeVEGKIHEAIVRKAVKERASVIGMASRT-GTVAATLLGSATRGVVRHSPVSVWVFRA- ->tr|A0A0D6AGR5|A0A0D6AGR5_9CHRO Na+/H+-exchanging protein OS=Geminocystis sp. NIES-3708 GN=GM3708_2417 PE=4 SV=1 ----LRLLAAIDNSPLTNTVLLKVAELARRSNAEVIVLHVVEQDDPQilQYLEaQTQTLLAD--I-RYRFITTVGVIPEEIVKVADYYKVVELIIGKRGHNHWENVLISSKSQTVLETSAIPVILV--- ->tr|A0A1H4KZJ3|A0A1H4KZJ3_9BACT Nucleotide-binding universal stress protein, UspA family OS=Terriglobus roseus GN=SAMN05443244_1417 PE=3 SV=1 --KPQAVVLGTDLTATSGVVAGTAIEIARRLDVELCILHVFQYLIhhryrmpvsWmlEEVrrdinakLRRLKKRAEDSQCSASTKVIESEDPAGSLLKESARFERAILVLGTHARDPIERFFLGSVAEQVLRTTRFPVITVGP- ->tr|A0A0R1L5R6|A0A0R1L5R6_9LACO UspA family nucleotide-binding protein OS=Lactobacillus koreensis JCM 16448 GN=FC99_GL001273 PE=4 SV=1 --FFRRILITIDEddRPSTSRAFRFALTMARDYQAHLGIASVLESDDIsiYeslmptklnekrdhlrSIVQEYAAKAKAFGVNDVRSIVAEGgDVDDVVLQkIIPDFQPDLVVCGADVDFASHG-HPGAIGLRLAKKSDVSVIVIR-- ->tr|A0A0G9GN94|A0A0G9GN94_LACPN Universal stress protein UspA OS=Lactobacillus plantarum GN=WP50_26545 PE=4 SV=1 --VYRRILLTVDEddNTSSERAFRYATTLAHDYDVPLGICSVLESEDIniFdsltpskiqakrkhveDVVAEYVQLAEQRGVNQVEPLVYEGgDVDDVILEqVIPEFKPDLLVTGSISIHFNEE-INYGKSKN-ARATCLSANFTD-- ->tr|K1YED0|K1YED0_9ZZZZ Universal stress protein Usp OS=groundwater metagenome GN=ACD_73C00798G0008 PE=4 SV=1 --PPQKIVVPVTFEEKTFEVLKNLLFQFPEAQTEYHLLHILSEPDLYGVykdilnnpldmnvdlLvKMAQQGLdnlaKKVFQIDITKKILQGDMAEETRNYAQLIGADLIAIPTHHRGGIKHFFLGSEAEKLVREVNNNVLCIS-- ->tr|F1WN98|F1WN98_MORCA Universal stress family protein OS=Moraxella catarrhalis 12P80B1 GN=E9O_03364 PE=4 SV=1 --MYQHVLLVTDLKDDTDLVAQKAKWiLDLQPQAQLSVLHIVEETMLgfgYelipasalhehiddERCQTARIRLadvlARNHLQAHHINIKTaISGRKGIVDYCQAHAVDLVVIGRHKRTGLSAWIAGATADSILPDIDSDLLVVQL- ->tr|A0A229H3U9|A0A229H3U9_9GAMM Universal stress protein OS=Moraxella sp. VT-16-12 GN=CEW93_00610 PE=4 SV=1 --MYQHALMVTDLNDDTDLVAQKAKWiLESSPATQLSVLHVVEETMLgfgYelipatalheeiddERCRMARTRLaevlARNNLQAHDAKIKTaISGRKGIIDYCKSHAIDLVIIGRHKRTGLSAWLTGATADSILPDVDADFLVVQL- ->tr|A0A1F3WY99|A0A1F3WY99_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RBG_16_58_11 GN=A2Z01_10690 PE=4 SV=1 -LTAKTILLAYHGTEGAKRAEALAYEIISREGGRIVHLLIVPeDVWvgmqgddWlnnastrdtyGSYVegvleKDAaeqVAVVeahcKQHGL-AYTPILRLGDPADCVIAAAREEKVDLVVIGPPRSKKESGLRSRMELDTLGRGLPVPYVVACG- ->tr|Q1CX24|Q1CX24_MYXXD Uncharacterized protein OS=Myxococcus xanthus (strain DK 1622) GN=MXAN_6935 PE=4 SV=1 ---VSRLVLGTDFSLRSEFALARALRLPLAHGSVFCVLHVAPVLDGQegpggtlsgaRCLRKAvssvCRRLRNRVDIDVREELGRGDPVEVASAVARMSGAELVVLGRPHvTYPVRALAEDSTVRRMVRHLGVSVLVVVPH ->tr|W7BXN1|W7BXN1_9LIST Universal stress family protein OS=Listeria grandensis FSL F6-0971 GN=PGRAN_00015 PE=3 SV=1 -----KIGVLIADDQLSKKIMEKTIGLCREFavPPEITLIHVVNMKGIAedievgvdleGdLITDAQKMlaekgtvLEAARF-GYKTAILNGFPAKEVTKYANDGKLDMIIMGHHDLSLMQKVTIGSVAKKIIEDATFPVLLI--- ->tr|A0A1J4SWM4|A0A1J4SWM4_9BACT Uncharacterized protein OS=Elusimicrobia bacterium CG1_02_56_21 GN=AUJ51_05065 PE=3 SV=1 --KIKRILVPLSGSLVSDVSFYAALKIASKFGSKIIPAHVAKDGAAAglrgaAFLNQVCAQWSSDAY-SLEPLLVHGEVKKELVSLCEKGNFDLICLSSTKFNPLAKLSGDSFSFNIIYATTPPIILMRP- ->tr|L0FWR3|L0FWR3_ECHVK Universal stress protein UspA-like protein OS=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) GN=Echvi_0795 P --TFAKITLALDFSSYTEKLLQLGTSLSKKVHSEILPVHVIKLGvqyfPYIknykKiseeLEKEALKDFKklqKrFHLhAPLTIVKDNEQHiSRLIYQNAVLNASNLIIVGNKGKKNEGDLLIGSVAEQLIAYDkNLPVWIVK-- ->tr|A6GC05|A6GC05_9DELT Uncharacterized protein OS=Plesiocystis pacifica SIR-1 GN=PPSIR1_24204 PE=4 SV=1 ----GPIVCAVTPEPASLAAARYAMQLGKAIDRPVVYIQAIALSVPMglpyvpeSAWVdlheqhmgRSQEtlaqWCDKNGLEG-EQKVISGPVVYELIATARRLDGCMIVCGSRQLSTAERLWTASTGMGLAAGSHLPVAIVPPE ->tr|A0A1F7MKP7|A0A1F7MKP7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RBG_16_73_20 GN=A2W08_01830 PE=4 SV=1 ----GAVTALSALTDDSTEACRFAAAFAERAARPLALAHVANDPRLDaaahiprSTLDrmaadfaaAGRAelphWLEVNDLRPMVAIVLQGDLVSSALAFADVQRAPFVVVGAHAPTGLDRVFAPRVGRELAAVSRVPVAIVPPV ->tr|A0A1G8Y0D6|A0A1G8Y0D6_9EURY Nucleotide-binding universal stress protein, UspA family OS=Methanoculleus thermophilus GN=SAMN04488571_102148 PE=4 SV=1 ----MKILVLIDGSKWSQKAALHAIKLAKRKNAEVVLFSVLDIAEAKamafnfctqsgicemlkdyegRIWNDmkksiaddqnnILTRYRGEKI-LCSGKIVEGNIRDEVIKEANSGGYGLVVMGAFGRSGKNR--ISALLEQIGGAVKPPLLVVR-- ->tr|A0A0F7HNB1|A0A0F7HNB1_9STAP Universal stress protein OS=Salinicoccus halodurans GN=AAT16_10625 PE=3 SV=1 --MYKNILLPYDFGNSFTNVPDELVKLTGQnEDAVITIFNVISETDQADnvkyhgkhfedIckdkvedLKPFTDQLNERGL-KYRTSFKTGRIIPELMNEVHENDYEIVVMSNKRSKRDIKHVLGHVTHKLAKRVNIPVLIIK-- ->tr|C0QFQ3|C0QFQ3_DESAH UspA13 OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=uspA13 PE=3 SV=1 ---HKNVLIAFDGTREVVEAVRRMSRLISNRGYQLLLCHASKNSAdMdk-plslkndQFFKQSVECLTSAGFTegQLTCELIssEGDLTENIVNRAREGGYESILVGRRNLTFLKQFFHGRVGDKIFQAAGnQVVWVV--- ->tr|B2A6S3|B2A6S3_NATTJ UspA domain protein OS=Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) GN=Nther_0609 PE=3 SV=1 --MFKKALMPLTLREQQDEFLSSVSLLAKLSTNTVHLCHVIDSGFTkyslvSNKIKLYKNILADKfpSL-NVSSEILSGHAGSKIIESAKTSESEFIYLPASQRHRLGQLLIGSTASDVVRLSDRPVFVHK-- ->tr|H1Z0P2|H1Z0P2_9EURY UspA domain-containing protein OS=Methanoplanus limicola DSM 2279 GN=Metlim_1188 PE=4 SV=1 --MFERTLIPVAKGEKTEEIIKITDTLANLGMNSAVLFNVHEPESIfsknsYSWFDNMMEELEGAGL-PVEAKTGTGHTASAIAEAAMFENADAVYMKTRRKWHIETMLLGSVSRDLLRMTEIPTFVHK-- ->tr|A0A1Q2HRU1|A0A1Q2HRU1_9BACT Universal stress protein F OS=Phycisphaerae bacterium L21-RPul-D3 GN=L21SP3_02006 PE=4 SV=1 --MFNTAVIKLDLKEPAEKLLEMAEFMQHFGTKTLHIISTADNHG-nrksiNAKTEEAAEKFRSLGY-SCQVHIRRGNPATQTLKLAEEIKADYIGLYWIPASVIRRALLGSVDAEILWRSSMPVFVYK-- ->tr|A0A226BUS2|A0A226BUS2_9FIRM Uncharacterized protein OS=Natranaerobius trueperi GN=CDO51_12285 PE=4 SV=1 --MLQKALLPITLQESKTDILFYVTLISKLGTKRVHMCHVVDSGFAnykqlSNRIQVFEQWINENffNL-EITSEITSGHTASKLLSSAKNSRVNYIYLPASKRHRLGKILLGSTAADIVRLTDLPVFVHK-- ->tr|A0A0Q6PJ06|A0A0Q6PJ06_9MICO Uncharacterized protein OS=Microbacterium sp. Root322 GN=ASC55_02280 PE=4 SV=1 --MPARYVLALKGRGGEETAHAWAESHAAAAGVPVVRVHVATGD-DAD-F------AHPEPHRTTDVILPRGPVPEHLARFLQ--DDDALVISTGKTGFIHSRVFGTMSLRIAAVARCAVVVVPH- ->tr|A0A1H4IRX6|A0A1H4IRX6_9MICO Universal stress protein family protein OS=Microbacterium hydrocarbonoxydans GN=SAMN04489807_0214 PE=4 SV=1 --SRSRRIVGIDGTATAETALRWAARRSTDDGAPLLLAHVGPFLGQS---DASvledarAIIGAEHAGLAVESRDLRSPVWKALSEIAD--PDDVIVIGADTAGLGRSRVSGALSVQLAIRSQCAVAVIPD- ->tr|M3PVV8|M3PVV8_HELPX Universal stress family protein OS=Helicobacter pylori GAM96Ai GN=HMPREF1430_00225 PE=4 SV=1 ---LMNILFGISDTQECYNAIKFAVKLAHSlKEVRFTLLHVSMEVFIYsesgmmdyGqtealeeekakaLLKQFEDAFKKENI-ECESVLKSGDLIDVVLDMAK--DYDLLLIGASESNLL-YRLFISHQNSLVEQSSIPVVIAK-- ->tr|A0A0Q4B780|A0A0Q4B780_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_04980 PE=4 SV=1 --DIRTILFPLDTTFESRQKTPYVARLAKDWNADVKILAVMESANKavraklQSYLAQVESYLDDRKVRHAAQTVQDADLVDLTLEQAASTPNSLIAITTRDKEAPRIFLVGNKPQRLISQSPVPVVAVAP- ->tr|A0A132I2L9|A0A132I2L9_9BACT UspA domain-containing protein OS=bacterium F083 GN=F083_350 PE=3 SV=1 --SLEHIVVPIRVSTSSREKIRPASMMARIFGSHVHILGLQDIPAEeqtlHAYMKQSADYLEAEHIPHTMTVRKSTNACDTILSYAYEINADLLVIHTEQDKFVKQLFLGTNAQQIVHKSQIPVLSLHP- ->tr|A0A1F5IWH4|A0A1F5IWH4_9BACT Uncharacterized protein OS=Candidatus Dadabacteria bacterium RIFCSPHIGHO2_12_FULL_53_21 GN=A3J42_03200 PE=3 SV=1 --GFKRIIVPVDLSHGLGKSFDYAVDLAAAFGSTVHVANVVETGYQkypselAEQLRgFAHRELKEtvgsTRLkDDLIINtVIAPNGWRGIVDFAFEKKADLIVIMTYGGGRFKKEFIGSVAEKVIQEAHCPVITMTP- ->tr|A0A1F6VHY9|A0A1F6VHY9_9PROT Uncharacterized protein OS=Candidatus Muproteobacteria bacterium RBG_16_60_9 GN=A2W18_07160 PE=3 SV=1 --TMVRVLIPVDGSRNAQQAVRHVVKDYMKNnELEIHLLNVQPPFSRHvasfvrkrdrdayhreqaeQALSDARALLAQYQV-PFHTHVAIGERAPIITDTARRLNCHHIVIGTARKNSLTRMLQDSVTNRVLELTTVPVEVVAGD ->tr|A0A0H0XLP7|A0A0H0XLP7_9SPHN Uncharacterized protein OS=Erythrobacter marinus GN=AAV99_12700 PE=3 SV=1 --NEPRLLACIDDLDGVHSLAPHALAVACSLGLKVTFARVIELRRHfsspadpitWHsRQCAERENLRKlvsgQSrepaeggalpaprsgtDQAIDSVLLAGNPGEELADWAKAHDTSVIAMHRRD--SHNGPGLGATAQALMNDGNSSLLLVPPK ->tr|A0A0F7KUE2|A0A0F7KUE2_9SPHN Putative universal stress protein OS=Altererythrobacter atlanticus GN=WYH_02931 PE=3 SV=1 --SGASILACVDDAPASAAVVLHAFAVGRGLELPITLARVVETSPQiglpadpveWRhRRNEYRSQLRRiaalPPgaSSPAGSILLTGAPADRLSDWAIEHRVPLLALATHGHSSARQNGLGPTAQRILQRAATSLLLVPPG ->tr|A0A074N683|A0A074N683_9SPHN Uncharacterized protein OS=Erythrobacter litoralis GN=EH32_12085 PE=3 SV=1 --DAAAIIACLDLSPHSQRVARLAAFLARETDRPLILFHAVSDEQPagglpdpleWHlRRSRARRFLEEmaasIEnfPGEIGIGIKEGQWQAGLAELCAMSGPATAVIGKSSV-GDH----VHLSASLLESGAGSLLVVPAS ->tr|W0A2I3|W0A2I3_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_01915 PE=3 SV=1 --GGFNIVACVGRGPHADFIVPHALAVGKALGAPVTLLQVLEAQAVrdprpdpieWDmRRHDARKLLGGlamvAGdpSGRADIALAEGRTVDEICRYANGKAECVIILGRGAGEDVDPRRIGSTVHNVAGRAPGSILLVPND ->tr|D9PJA7|D9PJA7_9ZZZZ Universal stress protein OS=sediment metagenome GN=LDC_1616 PE=4 SV=1 --MYQGILAAVNEFINSELAARYAIALAKSCRAKLFLVFIAEDRIDKDAFrhaESALgrlfMEAQGQGI-EVESITEKGSPLRTISAIVKKEQIDILFAASRREDVSKRFFQRTLARDFMLRLPCSVAMVRV- ->tr|A0A1G1FME7|A0A1G1FME7_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_42_7 GN=A2X59_04115 PE=4 SV=1 --MYKKILSAVNEHLNSEISARYALELARVTSSRIYLCYIAEKNVSEKAFrqaEETVrrlfLRAEDMGL-KVESIFDTGDPVTKIREIVKTEKIDIVFSATRREDVQKRFYAGTIARRLSLNLPCSVALVRV- ->tr|A0A1G0LBI3|A0A1G0LBI3_9DELT Uncharacterized protein OS=Geobacteraceae bacterium GWB2_52_12 GN=A2X80_04820 PE=4 SV=1 --NYRTIFTVVNEHTVSTVAGHYAIALAAAGPSRLVLYSALQKEASPASIhraERHLeqlfKEASTLAL-PVTRITESGLITRLLPLRADAEHTDLVLYPLTPDEQYHNLLRQQPVHTLLRSIRSDLAIMRI- ->tr|A0A0D8CNF4|A0A0D8CNF4_9GAMM Uncharacterized protein OS=Thalassomonas actiniarum GN=SG35_29030 PE=3 SV=1 --SADAILLALDFLASStekqqlnKKLLEFARDYADKMAIELHCCFAISPPKVLSdtgfidpeeYAQKStalaketaSVLLEPYQIAQQHQHIKIGSSDKVITGIAQKINAGVIIIGSMGKSAMSGKVIGNTCEQVLHISKKDVLVLGL- ->tr|A0Z498|A0Z498_9GAMM Uncharacterized protein OS=marine gamma proteobacterium HTCC2080 GN=MGP2080_09818 PE=4 SV=1 --KGSAIMATVDLEATAkakqalnVDVITSARHYAEMLQVDLSVLCVIDVPTLLVdldlidakaYAKERikelqpalTALAKKTGLPLSKFQLKRGPVAKTIVSEAAELKAQLVVMGTVGRRGVRAQVLGNTAEEALQLLKTDTLTLKP- ->tr|Q1NMS2|Q1NMS2_9DELT UspA OS=delta proteobacterium MLMS-1 GN=MldDRAFT_1145 PE=3 SV=1 -TLERKILVALDGSRHSRHTLHYLALLFARrPEVHFHLFSLVGGVNlppggeWLeeserlnmlspqsrqkltthqGYLRQGSEFLASRGVEpgRLssEVKISGDSLAEAIIREARRINCDAMALGRRGMTRVEEMLLGSISNHIFEKCHdIPLWVIDG- ->tr|A0A0M4I965|A0A0M4I965_9BACT Uncharacterized protein OS=Hymenobacter sp. DG25A GN=AM218_15800 PE=4 SV=1 ---MKTILIPLTLTASDEYALAYANKLAVRWRANLVLLYCQPGPALsstdeDallTRMQNHVERMRyqqlvrQDARrLHYHFRALAGSLPEHIAEVVSQNAADLVVMSLEQTHCPAQAMTDNHPVRVSSLVRCPVLVVPPG ->tr|A0A1S8W7D8|A0A1S8W7D8_9FUNG Uncharacterized protein OS=Batrachochytrium salamandrivorans GN=BSLG_00800 PE=4 SV=1 ---SRTLLIATDFSFSSTSVLDWAAQNLTKNGDHIIIIHSIQDVYsgsvVYhddvsycsdidEathisndinfaqvEMESATSFLKEcvygfeksliaSNVtdYSIQKVVSNGPPGPVIVAKAEEYNPDMIVIGTNGRTMLSELIMGSVSSYVSCHFKqCPIIMIQC- ->tr|W7YDM1|W7YDM1_9BACT Universal stress protein UspE OS=Saccharicrinis fermentans DSM 9555 = JCM 21142 GN=JCM21142_31209 PE=3 SV=1 --GINKIVLPISQRKSSRQKVPAVVGLAKLFDAQIYVVGVKEKGYSLansrvkVFVKQTVKFIEKNTdIKVDSQLITEGKRADVLLKYASTIDADILATGMHHSGNPFENIIKPFVNQLINESDCPVLAVPT- ->tr|A0A1I1YMF1|A0A1I1YMF1_9BACT Nucleotide-binding universal stress protein, UspA family OS=Thermophagus xiamenensis GN=SAMN05444380_10846 PE=4 SV=1 --NPHKVLLPIDYHKLARKIVPVVAGFAKLLKAEVSVVALQKKSKWLipgrsnIYARQAERYIQNNTsLNVSVTNFNWQGDVKNILSFAREQSASVIAIHLIKSTNPFESFFRPFANEILNTSDIPVLIVPV- ->tr|C0ARF0|C0ARF0_9ENTR Universal stress family protein OS=Proteus penneri ATCC 35198 GN=PROPEN_00370 PE=3 SV=1 --MANKYLVAIDLLEdSRIQRMIEDiHFLARKPENYFHFITVMPNLRSletyglncdsPSVIEkkqQAlvllTEKLEqcvtqQFNLpkEQYQCHAVIGTPNYNILELAEKIDADTIIIGSSSRNQR-NILLGSTADYIVNNTSRSVMVIR-- ->tr|A0A0P0CYW8|A0A0P0CYW8_9BACT Universal stress protein family protein OS=Rufibacter tibetensis GN=DC20_14375 PE=4 SV=1 --DIQKVLVPIDFSDTSVHALRLSKNLSDQSNLQLEIMHVYRLPRQfFpliseeKAVkkavEIVKKkfadLQKKHQeIANVPYTLVRaanKSIAERITLHLEKGGHDLLVLGLKGNNPLPSLSLGSVPTEMYNtDIKVPLWLVY-- ->tr|A0A0W8FKL1|A0A0W8FKL1_9ZZZZ Uncharacterized protein OS=hydrocarbon metagenome GN=ASZ90_008795 PE=4 SV=1 --KFKNILYAIDLDSKNISSLGKALEFAQFLNCSIHILYVNDIGAGYRhptDREDAVAlKVKEvipeSmlENLDIIYAVSKGNTAEEVVKYAQGNDIDLIIVGHKHRGKLYSSVFDSTDVNIVDTAMLPVLVIPE- ->tr|A0A1G3QYV6|A0A1G3QYV6_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_16_49_21 GN=A2W19_10325 PE=4 SV=1 --NIKNILYPINLDSKNVSLVVKALEIAKEFKSRLHILYVNDPDAGYRhptDREDAVAlRVQEtappEllESTTVTYAVSKGKLDNEVTEYCKNNNIDLIITEHKHKNKLYSMLFDTPDENIIDAINLPVLVIPK- ->tr|W7QWB8|W7QWB8_9FLAO UspA domain-containing protein OS=Cellulophaga geojensis KL-A GN=KLA_10573 PE=3 SV=1 ---MKNILVPIGTSTESHETLQYAVDFAKNFDATIYVMEIFNVKSaGAgslanatDKiEKNSREQLLdvvskvdKKGT-EIKIATYQGDIIEGLKKIDKQfLGIDLIVMAPRSNDINESNYLGNTSGKIIKQTDIPTLIVPK- ->tr|I3C3R7|I3C3R7_9FLAO Universal stress protein UspA-like protein OS=Joostella marina DSM 19592 GN=JoomaDRAFT_1244 PE=3 SV=1 ---MKNILVPIGTSSNTINTLQYAIDFAKFFDSKIYLMQAFTFINKAgsianveDVvAKNTTEQLEevlnkvdKKGV-SVTITAYNGEVLDGIKAVDQQYGIDLLIMEPRSTDIREEVFLGKTTGKIVKQTNIPTLIVPE- ->tr|A0A177NS60|A0A177NS60_9GAMM Sulfate transporter OS=Methylomonas lenta GN=A1359_20595 PE=3 SV=1 --RIQRIIAPIDFSPVSADSLTQAAAIAAQYKvPEILAIHVYDDESVVRYEehelikrgEEkvrFAEIMgsvDTHGV-RINPLFmESIKAAEEILTEAANYQADLIVISTRGHSKAASILLGSVTSSVMSDAKIPVLAIKH- ->tr|A0A0S8B8W9|A0A0S8B8W9_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12300 PE=3 SV=1 --KLDRMLLAYDGSPKASEALFVATYFAARWGAALSVLTVETNNTDVNALNRARTYIEQNGVSGANFILKSGPIGDAILETVLSEDIHLLIMGGFGLRSVRRLVLGSTVEQMLQQMRQPILICR-- ->tr|A0A0J1K718|A0A0J1K718_9GAMM Universal stress protein family 1 OS=Photobacterium ganghwense GN=ABT57_06140 PE=4 SV=1 -MSFQHLLLPVSPEQTLGDAYHEALQIADTKSAKVTLVTVIENIDELkeishysctalSLLDKVtkvshqalerhVHCLKVkYPSIKFSVIVRLGIPFVEIIKVANEFKADLIVIDTRCQNKTQACQRGSTIRHLMRKSAIPIWSCAI- ->tr|F9T245|F9T245_9VIBR Universal stress protein family 1 OS=Vibrio tubiashii ATCC 19109 GN=IX91_16790 PE=4 SV=1 -MTFTQLLVPIAPGQEIDDSHHQAFQFANNCSANVTLLLVIKELAEFkeifhlsgsslNVLDQAthhfkdhlaqqARTLSEqYANIRFTTKVRVGTPFIEIIQEADESNSSMIIINSYRESKQDACERGSNTLNLMRKSEVPIWSLSR- ->tr|A6BZN4|A6BZN4_9PLAN Universal stress protein UspA OS=Gimesia maris DSM 8797 GN=PM8797T_21648 PE=3 SV=1 -QSINSILVGVDLthadrlvasdlNEQTAEAVERAIWVARMFNAKLEFFAAIDLSAH-tkHLIQEDkdhlhknvtdeaNAVMqtlieQAkAQGVDSSSKVALGPPWREIILEVIKNNHDMVLVGT-RPHGFTGRLFGGTVMNLFRQCPCPVYAVKV- ->tr|A0A178K215|A0A178K215_9GAMM Universal stress protein OS=Photobacterium jeanii GN=A3K86_19470 PE=3 SV=1 -MNFSHLLIPIVPEQAIKESFEQVFNIADQQASHVTLLAVIEELAEFkeiyrysgttlNILDKAtqvyhdalkqhVQTLKHrYHNIHFHTQIRIGIPSIEIIKQAQASHASMVVIDSHRENKTIACQRGSNTLNLMRKSEVPIWSIST- ->tr|E1TJC1|E1TJC1_BURSG Uncharacterized protein OS=Burkholderia sp. (strain CCGE1003) GN=BC1003_3802 PE=4 SV=1 -TTLSHMLLLYDGTAESQAALSRCKQLSLALKAHVDVVSVVDPDSAnancagmlselayayleelgRRTLSTAVDELIQHGV-TAHGYLSVGCKADAIFRHAVSSPPDIVVIGHRLQRGLARWWRErPVHVDLADRLRGSTIVT--- ->tr|A0A1G3QGC1|A0A1G3QGC1_9SPIR Uncharacterized protein OS=Spirochaetes bacterium RBG_13_51_14 GN=A2176_13250 PE=4 SV=1 ---FSHVIYATDWTAASEKALQLLLHFNKIL-GELEIVNVINRKLTVKDMRELkekmartRKKCLDAEI-DAEAHVYAGNTPVEILTAAKDYKGTIIFVGGRsKKNPIKRILAGSSTCKIAENAPVPVFVIP-- ->tr|A0A0F7PBQ2|A0A0F7PBQ2_9EURY UspA domain-containing protein OS=Halanaeroarchaeum sulfurireducens GN=uspA6 PE=4 SV=1 ----MKVLLGIEGGENSIGVLRRTVERAQRAGDDLTVAILEDEgADqsADAFESDVRSTLAEADC-EADIRRLEENGGSELVRTAERDGFDRIVLGDGKQTPMEKIRLSHLAEYVLLNSPVTVTLVR-- ->tr|A0A126QLZ3|A0A126QLZ3_9DELT Universal stress protein UspA OS=Pseudodesulfovibrio indicus GN=AWY79_07325 PE=3 SV=1 --MFKDIIVGVTPTGIDACAVKAAIRFAERFESQLYLTHVAGME-qgWGsiehlapsgetdQIGTKIremyAEYLG--ITPGAQVVVVPGIPHSELLRLARQKNTDLIVMGPHTQEYEekrskMWGMAGSTLERVSQRARCPVMIVHK- ->tr|L8HAR3|L8HAR3_ACACA Cyst specific protein CSP 21, putative OS=Acanthamoeba castellanii str. Neff GN=ACA1_327930 PE=4 SV=1 -------IVCVDGSEGADRAMQFALRESPP-DHRLMLLFGAYVPHKEelswgtfsvSSMREghywdkelpdvyikYTDMCQKAGRK-CDfihFHFdRMSKFGDSVCSIADRHHAQNVILARRRQseRSFLGRFLGSGSQAVVDRCGdIPITLVTV- ->tr|A0A1Q7EIB4|A0A1Q7EIB4_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_40CM_66_12 GN=AUH32_07015 PE=4 SV=1 --MFSKILVAVGGPDDAEETLSVVSGLAKAFNSEVLVVHMRERVVTSaatieketipeafrfgvkiadQLVQ---AGIKAKAD---IRGHRPDRLAEFILDEAKKFNAELIIIGGHHAHGMRDRIFGDIGKTLAHGSECPLLLM--- ->tr|A0A062UMJ1|A0A062UMJ1_9RHOB Uncharacterized protein OS=Hyphomonas beringensis GN=HY29_00985 PE=4 SV=1 -FAPKNILVLVDMkhKDHADKALNLAGWMAKAMSSNLTLMTVAFPLGKhisdvpekrkPEFLEYVRRQSEKLDVTIEPLFTIHESVVHEVVRVAEKRKIDLIILQSGP-TKMVEHVLGSKASSISLKSKCSVFVVR-- ->tr|A0A1E5SPN0|A0A1E5SPN0_9BACT Uncharacterized protein OS=Fabibacter sp. 4D4 GN=BFP97_05545 PE=3 SV=1 -MAIDRIIIPTDFSTCADRALELALSMATKDLSELIICHINPVAAGgdamffinaeildrtekevDQSFRELLDKFPKLKQVSHKFVQTTGFSVDKIRDVAEEEMADLMIMGTKGRNNRIGEFFGSVASGIMKRSDIPILIVPEN ->tr|A0A1G1FXR3|A0A1G1FXR3_9BACT Uncharacterized protein OS=Nitrospirae bacterium RBG_13_39_12 GN=A2Y97_03440 PE=3 SV=1 --QWKNIILVTDYSLKDKTVIDEALKLSKIYESNLIIVSGdTGEKNRDEDINIIMKQAEKEGI-AVEALSASGKLPDFIAALAKKRDADIIITGSPVNGGSRYFFKGSLIDQIFDRSICAVLVIKR- ->tr|A0A0F9Z5J2|A0A0F9Z5J2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0005440 PE=4 SV=1 -----------------HQLTDVAHSLAKLTGGDVRLFHSCYQAPVSGVYPLvvdkalyrekTAGLLAAFSLPEDALCISDEIVTQALPAYLKQQQASVLVMGAVSRSALDRFFVGSTAEKLLDRVDQDVLVVKPA ->tr|W4LK00|W4LK00_9BACT Uncharacterized protein (Fragment) OS=Candidatus Entotheonella sp. TSY1 GN=ETSY1_19485 PE=3 SV=1 -RDIRKPLLATDGSLSAMAALSTAIDFAVQLKLPLSVVHCASPPNRHDAFLDAIERKVASQGIACDVDICQGNAHEDLVRYACERDHDLLLMGAFGHRQIVEWLLGSTTQYLLRTSPIPLVLCHAD ->tr|A0A1F2WKD3|A0A1F2WKD3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_13_55_18 GN=A2Y75_07730 PE=3 SV=1 -KGKRDVVVPLDGSETSAQALGAAKAISEILGGALHIVHVSEMRIP---KKDLPALLKIEDESKYDIRKLSGEIVPAVLEFALETEARLIVMSSHGTSFKTQDILGSKAKGIAQHTTIPIMIIRAG ->tr|A0A0S8KMW0|A0A0S8KMW0_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SM23_84 GN=AMJ93_05240 PE=3 SV=1 --TYSRLLCPLDCSQRAEHPLPLASMLARSHRATLILAHVMRRPEMprrrplsdeeraarervvelnRTEARRYLDEMRSAMAaeqVDIQTRLLLSdGPAQTLHHLVREEQIDLVIMSAHGYTGSTSSTYGSLALDFIAYGTTPLLIA--- ->tr|A0A0D5C3Z8|A0A0D5C3Z8_9ARCH Putative Universal stress family protein OS=Candidatus Nitrosopumilus adriaticus GN=NADRNF5_1846 PE=4 SV=1 -NNYKKILVLHGGFEAGDSALAHGINLAKLSNGSVTILHVVNIPKYpmesisnklerielqkklqdtafhmkktmEQEFQKKIKKYNKNKVK-TSLVVLIGPTLQKVLEYEKKNNFNLIVMGKSKGSRSveSRSVVGGLTIKLLEQLRCPTLML--- ->tr|K9H3F2|K9H3F2_9PROT Uncharacterized protein OS=Caenispirillum salinarum AK4 GN=C882_3146 PE=4 SV=1 -RGRRAIVVGLDASPLSVSGLRMAAVVARRWGVRVEAVHVEDAAVARlsshpgvvtvcgltarsrplalapetitaalsaqaRAARDAVEAAKallrrragEGGEAELVFRSRRGGVTRELRAVAD--EaaPSLLVVGWTGQSRARwhrahGIRLGSTARALVQDPSADRVLVVRG ->tr|B4S4N7|B4S4N7_PROA2 UspA domain protein OS=Prosthecochloris aestuarii (strain DSM 271 / SK 413) GN=Paes_1921 PE=3 SV=1 -LSIKRITVALDGSSHSKASLNIATDIARALNAEINGIYVEDVNLLRmaalpfaeeidrlsgrrepvdsaglerslqlqaRQAGQMLRQAAERFRLVHSFRTLRGQVAAQVLAEAL--SSDLLVLGKTGKTPVCRKKMGTTAKAVITSGTTSILLMRPG ->tr|A0A0C1RJ58|A0A0C1RJ58_9BACT Universal stress protein UspA OS=Methylacidiphilum kamchatkense Kam1 GN=A946_09470 PE=4 SV=1 --MISKILL-FE---NVPFSLRMAALLASKLRAELLGLFIEDVNLLRlsslpfafeteihsaltrslepesllrrfrtmaSQMEQQIAAIAKELNIPWSFQTARGFLWMELIEAAK--NCDLIIVSQKGPFSNFLSFYEDPLFQLLEEAKKPVLFLPSD ->tr|A0A1F3TX13|A0A1F3TX13_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFCSPHIGHO2_01_FULL_40_29 GN=A2622_00285 PE=3 SV=1 -RTIKNILVAVDLSKYSQTVVQQARVLAKKINAPLTFVYAFKDTEMFEspfgvrkaevikYYDQLIRQKYALDE-SIPVVVKFGKPYKQIIAAAKNLKFPLIVAGHRGQSTWTQFFMGSAAEQLGLESPYPVWIHRGE ->tr|A0A098S8Q2|A0A098S8Q2_9BACT Uncharacterized protein OS=Phaeodactylibacter xiamenensis GN=IX84_07375 PE=3 SV=1 ---MRRLLVATDFSPAARTAFEYTLQLAAHLQAEVHLLFINkvvsaetslpeqhrralierDNREYGKKLQRWARHYPDQPReyvaaPNLHFHVRPGKAASGIIQAASELQVEAIVLGGREKHNIREHLFGSVTTQLIGRSPCPMLIIP-- ->tr|A0A1N6IH68|A0A1N6IH68_9BRAD Uncharacterized protein OS=Bradyrhizobium erythrophlei GN=SAMN05443247_03853 PE=4 SV=1 --KLDHVMVCWDGSRAAARAVADAMPFLTRSG-KASIVVADIQSAKSAdlPGADIATHLTRHGVNVTIERIPVskIDVSNTILSYAADTDPDLSGIPGCGNLFLAGRHVVCLPR---------------- ->tr|R5H3U2|R5H3U2_9SPIR Universal stress protein UspA-like protein OS=Brachyspira sp. CAG:484 GN=BN676_00975 PE=3 SV=1 ----MRVLFCTDGSKISFNALHNFAGWA--RDAVVDVISVIDWTFLPDgicveeegfasscanmadnILDCVQKEIDNSNLTFGQRIKHCGEAVESILEQIKTENYDMVLMGSHGKKGLQSW-LGSVSRDVINNISISSYISKE- ->tr|A3ZQS7|A3ZQS7_9PLAN Uncharacterized protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_20637 PE=4 SV=1 --MIRSVLLALDASEASQAALQLTIRFCRDhsqredmsnVAIHLTGVAVVDTPNICgpmavplgavtykkdrdevllakanaeaeVILAKFEADCAAAGV-PHTAVRSEGLPYEQIEAVSR--THDLIMIGQDTNFHYEThKTISETVRRLLLDNARPVVVMPKS ->tr|H0I2T1|H0I2T1_9RHIZ Universal stress protein UspA and related nucleotide-binding protein OS=Mesorhizobium alhagi CCNWXJ12-2 GN=MAXJ12_33934 PE=3 SV --MLRSILVALDGSPSSVEAGLLALELGKRHRAHVEGLGIVNSAWIQrpepvpiggmaykkaldltllktasdrvnAVLRTFGERAKDADFAAFETKRVDGDPRIQIEFQAT--AHDLVVLGRNSLFDVDGelYEMPLHIDKVIRGEPRPVLLVPPG ->tr|A0A1G3HWM9|A0A1G3HWM9_9RHOO Uncharacterized protein OS=Rhodocyclales bacterium RIFCSPLOWO2_02_FULL_63_24 GN=A3H93_14320 PE=4 SV=1 ---GTHPLIAWNNAREAARALNDALPLIENCD-EAMVLSFTARhEEGESCCTEVARHLATHGIKaKTEVmLVQDFGIMDMLLNRVTDRGADLLVMGAHGHIGFPFVSRGAGTRHILRHMTVPVLM---- ->tr|D6SQ42|D6SQ42_9DELT UspA domain protein OS=Desulfonatronospira thiodismutans ASO3-1 GN=Dthio_PD2259 PE=3 SV=1 ---MHRIVFATDFQQAAEKCCQPVFFLGE-LVPELVVLHVgeraADPYSEQLRREHVNAKLEElkeqysGYYRKVRQISRIGSPASHILDVVDEIQADAVILGRLNEPFPLH-VMGSTCARVVSRVNSSVLLIP-- ->tr|A0A1H2UUW6|A0A1H2UUW6_9PROT Nucleotide-binding universal stress protein, UspA family OS=Nitrosomonas communis GN=SAMN05421882_101813 PE=4 SV=1 ----------------MITALLDAVNIASNHNAALCIVHSEDGSDIEVDEKTDITILEKAktylNELNVETRLLDAKkeegingISNAIAAATFEWGADALVVGTTNGRGFEYFYVGSVAEQLIAKVGSLILLVRPK ->tr|A0A135GTS6|A0A135GTS6_9NOCA Universal stress protein OS=Rhodococcus sp. SC4 GN=AXA44_46010 PE=4 SV=1 ----MTVLVAVTDTPEGAHALTVGKEEAERLRTELLVLNLSLTEFA-------PTEIAVAS--GVDVLDRAGrearDPAVAVLDLIQERpDIERLVVLTGQGKKGTVDRTSLLAQVLV--RPARWRR---- ->tr|A7I3R2|A7I3R2_CAMHC Universal stress protein family OS=Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) GN=CHAB381_163 -SPIKSVLLAFDGTLSSVKIAGFIHNSPLFSNAKKYIINISEDEEKsKEALKIAKDIIGEEN---AKYVYINGTDaGEEIIKFRRANKLDLIATGSFSKNFLKKLIVGSVSQEVITNALVPILVVA-- ->tr|A0A0K1HDR5|A0A0K1HDR5_9PROT Universal stress protein OS=Campylobacter ureolyticus RIGS 9880 GN=CUREO_0067 PE=3 SV=1 -SEIKSALVAFDGGDAAIKTLHSIKDSKIFGQDLeYHVLNINKDEKKsKEILDIARDILKNEN---AKFVSLNGEVADELISYRRANNLDLFVMGSFSKGIFATLFFGSTSKNVVEKALVPVFVAQ-- ->tr|M1E4C9|M1E4C9_9FIRM UspA domain-containing protein OS=Thermodesulfobium narugense DSM 14796 GN=Thena_0371 PE=4 SV=1 --MSKTILAAIRDVMSDRSVLKMAIDLAKDEGAKLVICHVINRSEDlgvfnpaaeaalvykaERMLEEAIDIAKKNNV-DAIKVVKVGRPSERISELAKQLNASNIVLGNRKLKGIRNWLFSEFSTGFNLKNTTLVSVEK-- ->tr|A0A1N7S2F7|A0A1N7S2F7_9BURK UspA domain protein OS=Paraburkholderia ribeironis GN=BN2475_310075 PE=3 SV=1 --GIDRILVAVDLSPASLRAAEFVRNIAP-TNAHIRLVSVADNPRSLsslppkasaelyaaraELLRDAADALVQAKHvfsgrdlpleeDLIDLSKRGSDIATALIDAADDWCADLLIVGARQHHGLLRWVEGTVSRPLTIHSRCSLLIVPPS ->tr|A0A0S6VTT2|A0A0S6VTT2_9BACT Uncharacterized protein OS=bacterium UASB14 GN=U14_00353 PE=4 SV=1 -DALKHALLLYNGSPKANEALFVSAYLALHWDWDLEILLTTR---DPLLRSFIAQYVSRRNL-RATILRNtLDEQEDALSTLLSDHQRDIVIAGSSEALPIT------------KTISLPILIC--- ->tr|A0A170PJY1|A0A170PJY1_9CHLR Putative UspA domain protein OS=Candidatus Promineofilum breve GN=CFX0092_b0579 PE=4 SV=1 -ELPRRALLVHDTRRPLDEAIFIAAYLAERWGVALTVLPLSNGRNTHEIAAHISDYLALHEV-AAAFLDPiRPDAraVDRIIATGLGGGYDLLIMTGPARGQRTNYnqQLTAMNGAILQRWPHAALIAT-- ->tr|R6I411|R6I411_9FIRM Universal stress family protein OS=Phascolarctobacterium sp. CAG:207 GN=BN533_02138 PE=3 SV=1 --MFTRVLLAMDLTPKSEILLPCLYSLCPDTNTEIILAYVFDEEEDadpysssykkvYSKLQGYANELMRNGYEAVSIEMPWGEVFEEITRVGNDKEVDLTLVASHGKGFFRSALLGSTTFDLARSSKRPLFVAKTD ->tr|A0A0S7WZZ9|A0A0S7WZZ9_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium DG_8 GN=AMJ42_06340 PE=4 SV=1 ----KKVMLVLSTTTSSTPFITYSLDYAKKEGAELIVCFIIDEKVSKtvssiltyigfmgekmgenlrktllseyegrakDKLEEVDKLSKKKEV-DCRCILLEGDVVNETIKLAKKEGPEILfIMPPTEKSDVYQTFFGDAINKILRASPCPIKIINGG ->tr|A0A0F9QTN0|A0A0F9QTN0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0975500 PE=4 SV=1 ----EKFLLSLAARYYNEDLVKYALAFAKQREATLSVLFVLDEELTNgiidqlidvgfigdkpseelrgavlneyeeqakKQLDSIKTIAEKEGV-KISTSVVNGDFVDTTLARAIDNAVDLIILNRERKGAVSKLFKGSPVDKLIKNAPCEVKVFES- ->tr|A0A1K1NCH1|A0A1K1NCH1_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Sinomicrobium oceani GN=SAMN02927921_01137 PE=3 SV=1 --------------------------MAKLYNSEIHFFHLMKTPVDWvkldkqkekrypetlkeigvvkSKLRELEKKAEHEGLK-CRTFLQFDSGQKDILEHSGHFHHDFIVTGSSGTRGGIRELMGSNVEKIVRKADVPVVVVKDE ->tr|A0A1G1T3E6|A0A1G1T3E6_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8643 GN=BEN47_14895 PE=4 SV=1 --TPLTFIAFADGQASPHHCLRYANTLARAVAGQVVQLRVSEPSvtvpgrlmaepcapddlLCQATTAAELASVAQELRARCVAQVIPDLPPALVRELADRHHPLVFVLSQRYPDDEGDESLATTCAKLLQT-SYPVLVVPLT ->tr|A0A1G1TDB9|A0A1G1TDB9_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8648 GN=BEN48_07865 PE=4 SV=1 --KPLTFVAFAEDTAAPNHCLCYASTLAQSVNGQVLQLRVSGQSmttpgtltaslfepdgqQCQSTAT-DQASEAYKLHEHPAAQLPPDLPPALVQDLAKHHHPLMFVISQGPPDD-EDEEVVDACADLLQT-NYPVLVLPLA ->tr|A0A0C2FBT6|A0A0C2FBT6_9ACTN Universal stress protein UspA OS=Streptomonospora alba GN=LP52_24045 PE=3 SV=1 -SSITRLVVPLDGSREAESAVDPALRIARTLQVPVELLTVHDP-VRGRWARNVDETAAASAYDHVEVTVVgSGWAGDVIVDMIAEQAGTVVCMATHNRDRFSRLVAGSVTEYVLHTAPGPVLMVGPS ->tr|A0A1J0G0P6|A0A1J0G0P6_NOCDA Universal stress protein UspA OS=Nocardiopsis dassonvillei GN=A9R04_09575 PE=4 SV=1 -RSITRFLVPLDGTAGAAAALGPALRAAHVLRVPLELLTVRDR-VNRAWAEDVDAVAAGLDYDRVEVSMVgSGWPGDVIVDAVAEQPGTVVCMATHDRDRFSRLVAGSVTGHVLRQAAAPVLMIGPG ->tr|A0A1X3KLV2|A0A1X3KLV2_ECOLX Putative universal stress protein G OS=Escherichia coli H605 GN=EATG_02895 PE=4 SV=1 --MYRNIVIPVNVFSRddREQAFCHAQFFANVSSGHVHLLGFIPEYVRilergyvsdmhrleYVLRDQALRRLATlaeqlvLPEGFIHTYVYLGTLPEGVKELAEQQLEDVIVLGATQELG---------FVDMLRQFSVPLLLI--- ->tr|A0A0G4IV06|A0A0G4IV06_PLABS Uncharacterized protein OS=Plasmodiophora brassicae GN=PBRA_007098 PE=4 SV=1 -PHHRRVFVFVspdYDHEPSLLAWEWAQANVIRDGDLVAVVTVVPRPPGStvvpavgmlgaaslafeldalqeqrriqladarKTLARYAESVTPRGWRLETRAIEQadLSIPETIVAWSTKHHADEGVVGTRNLSGFKRTLMalvgkGSVSNQLAQHMPCPIVIVKP- ->tr|J3EVM6|J3EVM6_9EURY Universal stress protein uspa-like protein OS=Halogranum salarium B-1 GN=HSB1_31700 PE=4 SV=1 ---MTTFVLATNSVHTSALLCDYLDDRLQ-AGDTVYAVNSQRGGddtSAaevrdgEDALNAVTARLSGVADVETHQFVRENSPAEDVVGYAEEVDADELVIGVRKRNPTSKVVFGSVAQDILLTANRPMVVVP-- ->tr|A0A161SI63|A0A161SI63_9NEIS Uncharacterized protein OS=Crenobacter luteus GN=AVW16_08365 PE=3 SV=1 ----GFVVLAYDGSTSAARALQQFAFLGVGHERPRKVVAIHPDAAEaGRLADEGAAYLASHGLPaQPVPIASAARPRQLLLAELDSQHASLLVMGTFGHRSWLDRLFGAATETMIARCTCPVLLCH-- ->tr|A0A1W9V7I0|A0A1W9V7I0_9CHLR Uncharacterized protein OS=Anaerolineaceae bacterium 4572_5.1 GN=B6I38_04810 PE=3 SV=1 --MTKKILIPLTKSASSHKILDEIEKLVPIDNSKLILYYVTKPPKGSGfaapdyrsdyaleaagepvgpkkhpvfssqeedslesdvevALLSVTNKLKAKGYDVSTQVCFVDSVVSEIVRVVKRDKIDMIAMSTRARVGMSRFFFADIAQKVMQKVDIPVLMIHP- ->tr|V8D2L7|V8D2L7_9ACTN Universal stress protein OS=Williamsia sp. D3 GN=W823_07180 PE=4 SV=1 -APAVTVVVGYQPGRGGDEAIELGSGLADALGTSLVLVIATPKPWKTPsmarvdaefaeyaqrygddAEAAARTHLRTRaPGTGVSFRRVSEgSVSKSLHVALDELDADVLVLGTTHGDDGGQMSLGATTSRLMHSSSVPLALAPRG ->tr|Q0A8H2|Q0A8H2_ALKEH UspA domain protein OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_1516 PE=3 SV=1 -RLFRQALVLLDASLSSNEALQAALGLFARGEVALRGLYVEDRDLLRsaalpftrevggysgvcrplasdtlearlrdraQLIRTVLKRVARDYHHHLELEVTRDRVVSAALSLVR--DNDLLVIGRTGWASGQARALGSNARQLVRLAPCSLLIGTW- ->tr|A0A0K0XTD1|A0A0K0XTD1_9GAMM Uncharacterized protein OS=Wenzhouxiangella marina GN=WM2015_533 PE=4 SV=1 -LAGGRIVVLFDGSPGSQAALLQGLAMAQAQQRELVALYLEEAAQIAaaglavagevgavsgqlrplnaeaqaqalrirrRRAQACLDHLMGGPGHSLALDVRQGEAVGVLEALLG--PEDCVVAGRAGFATRHPGRLGRLARRLLSQLLRPTLLAST- ->tr|A0A1M4SIM2|A0A1M4SIM2_9GAMM Uncharacterized protein OS=Halomonas ilicicola DSM 19980 GN=SAMN02745148_00122 PE=4 SV=1 -RLIQRVVVLLDGGRRAQLLLDEVAQLAKREDAELVGLFVEDTELLRaaslpcggeiglisgslrpvapealerrlrqqaDRLQSLLAATAGRHALRWRLEINRDHLEAAALAATM--ADDLLVLYRAGWRHPPEGGFTSrTLSRMLGAAHCRVMMLGE- ->tr|A0A231MZZ0|A0A231MZZ0_9GAMM Uncharacterized protein OS=Zobellella denitrificans GN=CGX12_07370 PE=4 SV=1 --MIRHIVWYLDLSQAELEMLERVAEFAARHGARLRAVFIEDESLLRsaelpctrevslttgrvreldperirlqlrrrrEHIRQRLQQLARNRALEWSLEVEYGRREQLLARPPAS-RDEVPVLVLD-PATELPTWDRP--------PEHEVLLLSR- ->tr|A0A142VXJ3|A0A142VXJ3_9SPHN Uncharacterized protein OS=Sphingopyxis terrae NBRC 15098 GN=AOA14_07385 PE=3 SV=1 --MFRSILVIVDPDRraEATRLLEVAAELRRSFDATLTLATVMSEWSvmlraersvgaaglFEAAEARLAALAHSvAAVGDARYRVETGRAHRGILNAAASVNADLILLPSRA-PKWQDRLFGTTAMRVARNSSSSVFIIRD- ->tr|A0A0S8DDG7|A0A0S8DDG7_9BACT Uncharacterized protein OS=Nitrospira bacterium SG8_35_1 GN=AMK70_09315 PE=3 SV=1 -KRFKNILLITNKNDINSSNIIRAVSLARSNKANLTIADVVPGLPlmqrqlipspgiasvLSGLAEKRLNELTFmaqelSAKMDITPLVLQGTPYLEIIRVVMQQRFDLLIKISEPEESFTAKIFDSTDFRLLRKCPCPVWLLKPD ->tr|A0A081N3M5|A0A081N3M5_9GAMM Uncharacterized protein OS=Endozoicomonas montiporae GN=GZ77_21840 PE=3 SV=1 -HAFKTILLAVTRLHSSELELSQTFRLVSDNNARLIIAVFDQSLDvlqrlqflplegklEALCRKQLEEYTEElrakawEEGVQAETCIVPGKPRQVIGGLINEYGVDLVVKLADPCGPLARNQLTGNDLALLRKCPVPVLMMASR ->tr|A0A0S2T976|A0A0S2T976_9GAMM Uncharacterized protein OS=Candidatus Tenderia electrophaga GN=Tel_00190 PE=3 SV=1 -KRFNNILFVSEEPLDhNPAAFERAVALAEQHQARLSVVDVVPESParlqsiadelspamlMDALREERRDALAQlvaahGRGLAIDIQVLSGPHFLAVIRAVLRNGHDLVIKAAHDDTTFKERIFGSQDTHLLRKCPCPVWLLRPP ->tr|A0A1M4XDD2|A0A1M4XDD2_9BACT Nucleotide-binding universal stress protein, UspA family OS=Flavisolibacter ginsengisoli DSM 18119 GN=SAMN02745131_01425 PE=4 S --SFKTILVPVDFSINTEVAIKKALEVVDRQTGTIHLLHVnhqmksniitvvkrnyqdgyt---LPAEQMLSDWKKCMEDSiPTLKVDISLEHHSSIqMCIEKKTMQLKADLVVIGKKSNHFWLPFLNTVLPNELCEVTGSAVLTVKPG ->tr|A0A1J5TJ63|A0A1J5TJ63_9ZZZZ Universal stress protein family protein OS=mine drainage metagenome GN=GALL_29360 PE=4 SV=1 -MSYNNIVVAVDGSDASQEALDHAVDLARQSNASLTGIFIIDTQWAdfigndwqsakgarqgfldyirkeqEEQAEAAHAQFEQAtqGMEQSCFSVHAGDPTEVLLAQASSDNTGILVAGRRVFQVSGRPSLKSLAATLEKKASRPLILFP-- ->tr|K9GS05|K9GS05_9PROT Universal stress protein UspA OS=Caenispirillum salinarum AK4 GN=C882_1385 PE=4 SV=1 -QGRRAFLVVVDDSPEMTAAARFAARRAARSGGRVALLSVVEPVDGghwmfvgnlmaeearedaERRLQQVAATVHACSGERPELIVREGSLKEQLFKLIEEDdEISILVLGVAANGEGPGPLVQSLTGKNAGKLRIPVTIVPGD ->tr|M4VEP8|M4VEP8_9PROT Universal stress protein UspA-related nucleotide-binding protein OS=Micavibrio aeruginosavorus EPB GN=A11S_886 PE=4 SV=1 -GDGGVYLVVADESEEFNLALRYAARMAQSNRGHVGILHVISLDDVqqwsgvenrmkrelreqsEKFIWSMAKRVNELNGMIPAIYVREGDAKHDvMIDLINEDmTIKMLVLGASASSSGPGPTVAYFTGKGLAKMRVPVVVVPGH ->tr|L8JXP5|L8JXP5_9BACT Uncharacterized protein OS=Fulvivirga imtechensis AK7 GN=C900_01992 PE=4 SV=1 -AMFKRIIFPTDFSESSAKAFSYVLDVVRSHQSELIILYTYRlisgadgryygnkisikrerEEEANKQFEQLKQCYPELSDFEHHFLTEVGFVSDRISLAVERFNIDLVVLSESIQQQLKEKWEM-SDENLPGRFHCPVLLVP-- ->tr|A0A1W9WS53|A0A1W9WS53_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_89 GN=B6230_04815 PE=4 SV=1 --MYKKILFGTCLTEYCSNIFNYALNLAQENDAKLWIYYGLGRLNLDEagaeqaikkaeadVAQAYVQQMKDRDFNNYAINVSDGDVVSELSKLARNASIDLMVMGTSTEVPLamggssDVRPLGATIADALLWAPCPVMIIPPS ->tr|A0A199V333|A0A199V333_ANACO Uncharacterized protein OS=Ananas comosus GN=ACMD2_24843 PE=4 SV=1 ------VVVAVDSREESMKALRWALDNLRlGQPPPEPRAD---PGNCVKNLYHAIKNVT--------------NSRNMWYHLSSSFKMTGKYSSPLVREYRKRMFLGSVSKYCVNHVSCPVLVIKG- ->tr|A0A1V4TSB4|A0A1V4TSB4_9EURY Universal stress protein OS=Methanomassiliicoccales archaeon PtaB.Bin215 GN=A4E30_00615 PE=4 SV=1 --MLDRVLVTIDLTKASKVMLPFVQQLIDAGARKMTLFHVVQSSKYsmadDARFQEVKQKMEAYQGKldakdcEIDVHLHFGTTTYNILEAAREIDATLIVLGTTGKGYLRGVALGSTSEEVVKGSTRPLLLIPS- ->tr|A0A1M6E548|A0A1M6E548_DESDE Nucleotide-binding universal stress protein, UspA family OS=Desulfovibrio desulfuricans GN=SAMN05660830_01053 PE=3 SV=1 --SVQNIFLAYDGSAEAGIAARQACALAERYGSRLTAGIAYEMDMEafslspvvesaavektELAVESIKNIVASADVRDFDVAVRYGNPPhEVLVEEAQKSDAGLIVIGACSRSKLSHLLVGGVVHKLVYSSACPVLIVKEQ ->tr|A0A1C6L655|A0A1C6L655_9FIRM Universal stress protein family OS=uncultured Eubacterium sp. GN=SAMEA3545368_03795 PE=3 SV=1 ---MRKLLLPIDGSERSMKAAELVRLLYDKEDVEVILMTVRNDCEFvneESELETIREESLEifsnaekilAGY-HMKKIVDFGHIGNAILRQIEDEKITAVVMTRSTREGYFKH-LGSVTSYVLKYARCLIVIVP-- ->tr|B6AR26|B6AR26_9BACT Probable universal stress protein (UspA) OS=Leptospirillum sp. Group II '5-way CG' GN=CGL2_11238045 PE=3 SV=1 --PFKSLVLPYDLTPVPPGTMETLKNILHGEGATLHVFHVLDIYEETpmgyplppeysaemekvvcQEVKKLADLYRADGI-ETTSGVYRGRVDRTIIEVALHQKADGILLLSHGKGILGRILLGSASNSVLHHSPLPVILIKPD ->tr|F2NEX9|F2NEX9_DESAR UspA domain-containing protein OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_0432 PE=3 SV=1 -RPIQKILVAYRGSQCDQGALQFIAPLFAKQKPEITIMHVQETELGesEEFAQACVltgeDTLREWGY-TPIKKVAKGDFVDEILKAVAVQRYDLLVLGAYGHQRPKYLkIISDEALNLVRLTTRPVLVYRD- ->tr|A0A1X0L114|A0A1X0L114_MYCKA Uncharacterized protein OS=Mycobacterium kansasii GN=B1987_25685 PE=3 SV=1 ---MKPVVVGIDGSTAAITAALWGTDEAVSAAVPLRLISVIKTTHPcpedyerdlrhaVTSLRAAQAAVAATGKPiKVDTDTPRGPAGAVLVEASR--DAGLICVGSAGIGRYARSILGSAASELAEKAHCPVAVIRPD ->tr|A0A1L5PCH5|A0A1L5PCH5_RHIET Universal stress protein A OS=Rhizobium etli 8C-3 GN=AM571_PC00068 PE=3 SV=1 -GRIDTVAVAWDGSATLARALTGARVFLDK-ASRAVLISITDDKAIDADLrDRFAAVIRGAGLAieIVDAQSQGDPVATKIQSVAAQSRADLLITGGFGHSRLRELILGGVTRSLLNGLEVPVLL---- ->tr|A5UUW5|A5UUW5_ROSS1 UspA domain protein OS=Roseiflexus sp. (strain RS-1) GN=RoseRS_2033 PE=4 SV=1 ----MNLLIYAGPGPWRNEALATAAQFAGRVATLVTLVTGGGMSNA-PLLDDALARLRLPPDVEVRRRVVEGTPQEAIMTVVDEMTYHLVIFGRFQ-RPLERLLPLRRSDALTRRLRSAVLRVHG- ->tr|R7KMG7|R7KMG7_9BURK Universal stress family protein OS=Sutterella sp. CAG:521 GN=BN692_00345 PE=3 SV=1 -----HVGLSVDDSPFGPKCADYLIAHRHFFGkdATFEIINVVPDDPlyapdfvnegpippqmtweeiqgleFEASVKSPVEKFDIAGV-PVKAVKLIGNPEDVLPKYADE-HLDVMVMGTHGKGALRSLVFGSSTRAMIAATNLPILVVPNV ->tr|C6XIF3|C6XIF3_HIRBI Uncharacterized protein OS=Hirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) GN=Hbal_3092 PE=4 SV=1 ---TRKFLTLADDTQECFSAILFAAMRAKRVGAGLVIMRAVQVSGMghwrgldedmrteamdnaLAEVKSIARLIKDRIDIEAEIIVEIGKPEQAISRITNkDKTIKVIVLGSGSGRAGPGPLVSRIGRGkALTERPVAITIIPGN ->tr|A0A0K8P8C2|A0A0K8P8C2_IDESA Serine/threonine protein kinase OS=Ideonella sakaiensis (strain 201-F6) GN=ISF6_0199 PE=4 SV=1 ------VMVALPWRDASDATLYALRESVARSlglrpGARLACVSVLPPGGARGgpgpdgdgdgaagvpshrhllaRLHEWAAPLDQDAH-PTSCHVLEHgDVARALLDYAVGNHVGLLVMGAATHGLALQPVVPTLPIRVAMAAPCTVMLVKPA ->tr|A0A0S8BK38|A0A0S8BK38_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SG8_45 GN=AMJ68_03980 PE=4 SV=1 ------ILAAINLSSGD-ALNIEILRRAQQMaglqHSYITVVNVT-AVDVGMasgernaqlineqlvkarkKIATLIPRTGLTAA-QVGINVLIGdDPVGVIHRCVNDYGIDLVVIGCPEKNRLRKFIHGSTGYKILTSVKRSVFVVHAP ->tr|A0A0S8KWX3|A0A0S8KWX3_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SM1_46 GN=AMJ72_13555 PE=3 SV=1 ------IVVALDSASGGrvETINRALLDATLRLarmqPSMITVLTVLAPQDTGMadgareaqiinasyhsarnRINRLLPPSGSMSA-PIGINVRTGNVVEAISTCVADYGADLLVIGARERNALSRFLLGSTTYKVLTTLSCPVFVVRER ->tr|A0A177Q4K7|A0A177Q4K7_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCGC AG-212-E04 GN=AYO41_00930 PE=4 SV=1 ------IMVAIDTVHPDDERHAALRRATEQVlagtaEFRLVCISVLGLFGDAGgtvpadadadlhlehliRLRHWVDPLKLPTQ-RLSLHVLESlSPSAGLLDFARRNHADLIILGAPGAAQRGMAWWRSVASTVAANAPCSVHLVRVP ->tr|M7MXH6|M7MXH6_9BACT Universal stress protein F OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_03732 PE=3 SV=1 -YPIKRILVALDLTDMDVTLIQYAAFIAKNTPAEkIYFVNIIRNFHIPesvlkefpglmdtaiaerkeKMKAVVDAHFHAGEailtRFKIQYLVKDGAPARKLLQMSQDSDIDLIIAGRKVSLEG----SGVLVQRLARRAACNLLIVPEG ->tr|A3I339|A3I339_9BACT Putative universal stress protein OS=Algoriphagus machipongonensis GN=ALPR1_14244 PE=3 SV=1 -YLIKKLIVCLDQSPLDQTLVQYAEFIASVNQTKkIYFVNVIKNLTVPkevieefpnlvenminerkeAMENLVKENFKSTKGISFNYVVKEGSLSKKILKLADEKSADMVLIGRKVELPG----TGVASLRLARRASCSLLIVPEG ->tr|A0A1M6G641|A0A1M6G641_9BACT Nucleotide-binding universal stress protein, UspA family OS=Tangfeifania diversioriginum GN=SAMN05444280_11046 PE=4 SV=1 -YQLDNILVCLDLSDMDDSLIRYSNYLVEKFKPTtVTFLHVMKSYDIPeeiisafphlnepisevvkeELTEKINELFKHDKTTKTIISVKEGTTTDTIVRYAREQNITLTLMGKKIGYEG----QGGIVRKVLNIVPSSVLLISET ->tr|A0A1S1YZM7|A0A1S1YZM7_9BACT Uncharacterized protein OS=Flammeovirga pacifica GN=NH26_08910 PE=4 SV=1 -DKTQTALLPLDLTYIDDAIISYSLKASPLSQVKkIILMHVLKDNTEKdeveykgkllsrhdmaeaKMRDLVEKHKDLNDrNIVFEIHVSASNdPTSKILKYSKKKKVELIIAGKKNIAEG----SGTIARLLTRYAFCTVLTVSEN ->tr|A0A1S1Z4W5|A0A1S1Z4W5_9BACT Uncharacterized protein OS=Flammeovirga pacifica GN=NH26_19270 PE=3 SV=1 -SVFKRTIIALDGTDKDIPLLKHASKYIQRNEIEkIYFIHVQESLDLPeeviekypdmlspldesikkDMEELISEHLPFAKELNHELMIEEGDPAETIIKISKRKQASLVILGKTDKKNK----TGAIARKIASFSPASIMFAPEL ->tr|A0A0D3CND1|A0A0D3CND1_BRAOL Uncharacterized protein OS=Brassica oleracea var. oleracea GN=106292758 PE=4 SV=1 -REPTRVMVAVNESTikgkphpsiSSKRAFEWTLEKMVRSNAsdfKILLLHVHVVDEDgfdevdsiyaspddfkdmresnkskgLHLLEFFVNKCHEFGVS-CEAWIKKGDPKDVICQEVSRVRPDLLVLGSRGLGRFQKVFVGTVSGFCVKHAECPVLTIKRN ->tr|A0A077KJ32|A0A077KJ32_9FLAO Putative universal stress protein OS=Chryseobacterium sp. StRB126 GN=CHSO_2369 PE=4 SV=1 ---MRTILVPIDFTPTTENAVKAAAEWAKYYEyQNIILLKIAGESEFDylhiaeghsfvneesvnsllerteLRFDQLSQVVAEISPEvKVSRLLSDWAITRSINEVLKNePSIEMIILGSDDSTSSNESFVSENIIRIARTSPVKALIVPNS ->tr|A0A1C4DI76|A0A1C4DI76_9BACT Nucleotide-binding universal stress protein, UspA family OS=Chitinophaga costaii GN=GA0116948_105289 PE=4 SV=1 ---MKTLLIPVDFTTTTDNAVTFGGAWAKRYDyERIILLKTFYDNVFDnivvsaeyapvnqeyraqerqearEKLDQLCERLRSLaGPGvTVVTAESEAPLLRSILELVQAERPEMILLGSDDYKHTTGSFIAGHVISIAKASPVRVLIVPAS ->tr|A0A0P0GHF1|A0A0P0GHF1_9BACT Universal stress protein family protein OS=Candidatus Xiphinematobacter sp. Idaho Grape GN=AMD24_00191 PE=3 SV=1 -PMYHNILIPLENSIADSTILEHVCRLAHSIGGYLHLLHVASGWVARnydqlnlteseemkndlRYLESVAQALRKGGL-ECSYELAMGEPSNEIIRIAKEREVDLIAMSTHGHRFLGDFIYGNTVDRVRHLVGVPVLLLKAA ->tr|F8L8B1|F8L8B1_SIMNZ Putative amino acid permease OS=Simkania negevensis (strain ATCC VR-1471 / Z) GN=SNE_A11570 PE=4 SV=1 --KYQNILVPTRG-GRETETVQMACEIAKIHGAKVTALHVIEVPFSlpletplyhrtivaESILKRAEAIGREFNIRMDLKVINARAVDVAITDLVEKEHYDLLVMGTTMTKGGTAKGYGGVVERILKNATCPVWLCFSA ->tr|H0EBI1|H0EBI1_9ACTN Amino acid permease-associated region OS=Patulibacter medicamentivorans GN=PAI11_42120 PE=4 SV=1 --AYGSILVPLLGTALDDDVVQTAGRLAGGDdetdieegYAVIEAVWIHVLPMSlpidgpladgrikeAKqALSRAKAVGEEYeGVRVATSAVRARALGKAIVDEAARRGCQAIVMVAPPPtgrarsgragaalGArgg-RGDVLNEASRYVVDKARCQVILTAPA ->tr|I0INL6|I0INL6_LEPFC Amino acid permease OS=Leptospirillum ferrooxidans (strain C2-3) GN=LFE_1174 PE=4 SV=1 --VPHRNILVATSPHAPSPILHDIAKIAKSDKARVTVVTVLEIPLSlplnaplpeeeaiaQNTLELCQAIGVEGDILLDTLLIRSRSIGDSLVQVYTRHKADTLVFNDTNSsvsKSidaAIVRSGVPVTVWKIQSIMGRSGKKPGD ->tr|A0A1Q3NC28|A0A1Q3NC28_9ACTN Universal stress protein UspA OS=Solirubrobacterales bacterium 67-14 GN=BGO23_10950 PE=4 SV=1 --EYKSVIVAFPADqPFSEEVMATAAKLTSDRRRGIHITALLTVPTHlplessmakeekeaQSKIERAKLI---AGLRVSGRVerVRPGQEGYFLARQARTSKAAAIVIGLNSRrgVPq-YGKTL----ETVLRERPCRVIVVSED ->tr|A0A1Q3NC98|A0A1Q3NC98_9ACTN Uncharacterized protein OS=Solirubrobacterales bacterium 67-14 GN=BGO23_10940 PE=4 SV=1 --DFHNILVPIFGTRIDDDIVSTAGRMAAEGdpeqsdaHAVMTILYLIEIPLNraikdplpeevadaAQrATKRAKEVADEYeDVEVRVEIERVRKKGTGIVFAARRLGVDAIVMGAEPPspikggarlGGigdYRPEEIGPITAYVLKRAPCRVLLTAPG ->tr|A0A1G0DTV8|A0A1G0DTV8_9PROT Universal stress protein UspA OS=Gallionellales bacterium RIFCSPLOWO2_02_58_13 GN=A2Z65_06135 PE=3 SV=1 -RLYRNILVALDSSDYANAAMRDAAELACMAdAPVITGSHVYAAKLHDmrfrqmegglpeqfrqeqelerqrdvhddlitrglsiitdSYLDQAANECARLGI-EFKRSSLEGKNYRELVRETNSGRYDLLVMGALGLGAIKGSRLGTVCRRSARRSAIDTLVIKNT ->tr|A0A1Y3LUR6|A0A1Y3LUR6_9MICC Uncharacterized protein OS=Arthrobacter agilis GN=B8W73_09955 PE=3 SV=1 -KRNRPIVVAVRDTATGGPAVLWAARRAESLGVPLTLVHAVPDPALMPpgspygdvvvggrevLRAEANRISADFPALHVGTYLHCGDVVEALLGLAA--ESPLLILGSDRMDAVSGEFRGSVSLQVALGSRVPVVVVPSD ->tr|A0A0J1DBL1|A0A0J1DBL1_9BURK Uncharacterized protein OS=Massilia sp. WF1 GN=AB595_11200 PE=4 SV=1 -KPYAHAVFPSDFSPDSLDTLQAALRLL--PATRLTIVHAFHVPGEgqmraarvrdeaigacrrkaelaaQEAFAALAARLQPHPA-RLSLVLLPRPTGLAVAEYVNAVDADIIVLSGSQRWLVDDWSWQHRARELIEKTSSDLLMVTP- ->tr|A0A1M3QTS6|A0A1M3QTS6_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 40-81 GN=BGP13_06525 PE=4 SV=1 -NNFYNILIPIDFTVKNKWAITKAIELANSFNCNIHLVHVVFKPVFPlinidasnftpyashINMQTCREKLAElkaiykkqmVGEGEIEISLLQGHPQKQLKQYIENYKMDLVVMGLAKFNLFDRIISSISISLLAKKISVPILAIRSS ->tr|A0A009ZYP5|A0A009ZYP5_9GAMM Universal stress family protein OS=Acinetobacter sp. 479375 GN=J500_0057 PE=3 SV=1 -KAPTRFIFAYEYSPTCVKMMHRIAQSDLLRTLQCHLLYVGDHP---QVLKDPEEFLSHAGI-EVVTVYRYGDVAENILEYQREHGIQMIVLGAFSHSKIHQFFLGSIATSIFRNATVPLLVAK-- ->tr|A0A0X6ZKR0|A0A0X6ZKR0_9ENTR Universal stress protein OS=Enterobacter cloacae complex GN=ABF69_0212020 PE=3 SV=1 -MSYSHVLVSVAVSPESHQLVARAVSIARPHNARISLITLAAEPEMynqLAapmledirevLQEETQQFLRDlaekAQYPIHETVIATGELNAHILDMCRKQQIDLVICGNHNHSFFSR--AACAAKSIVASSQVDVLLVP-- ->tr|A0A1S8CMI6|A0A1S8CMI6_9GAMM Universal stress protein OS=Rahnella sp. J11-6 GN=BMI79_06440 PE=3 SV=1 -MGYYNVLVAVAVAADSHRLVEKAVSIVRPYNGQITLVSMIANPEIynnFAgpmfgdlralMEEETLLFMEElrsrTDYPIDNTRIIHGELGDCLTYANQRQPFDLVICGNHSDSMLSK--VTCSAVRFINTSRIDVLIIP-- ->tr|A0A0E4ANK4|A0A0E4ANK4_BURCE Uncharacterized protein OS=Burkholderia cepacia GN=XM57_23745 PE=4 SV=1 --MSKTVVVAINHNFT-DSFLASALETARHCDARIAAVHVVDLTHCYaglgdsnyglvvgamlaygrAALARAMTTLNDNPR-GADAHLLtlpvRGsHIGREIASVCEASNAELVLLGARKRVWW-QVIGEDVAATLRKATRTPVQIVRAA ->tr|A0A1P8KC54|A0A1P8KC54_9BURK Uncharacterized protein OS=Rhodoferax saidenbachensis GN=RS694_14050 PE=4 SV=1 --MYRKILVLVDNRQVTQSAIDQAIGLAQVHRADIFFFSVLPNYVYPavdmlpvadmsaddfraqaseeasRMLSAASAWAERCGVHNHRAMGAGADGAHCVAEAAVKRHCDLIVVGTEEQNAVVRLLSGSIVPGLISAATVPVLVCRE- ->tr|A0A0R1Q637|A0A0R1Q637_9LACO Uncharacterized protein OS=Lactobacillus nagelii DSM 13675 GN=FD45_GL000139 PE=3 SV=1 -----------------ITALERTAEYANKNNIQLDILYVLDPAIAGfgntqielsseslyhleeksiGQLEIIKRRLIISGSSiyQVHVHLRIGDPRIIVAqEFPTEYQNDLIVLSSSRKNHLQRFFTGSVSSYVIKNAQADVVVMH-- ->tr|H5SES2|H5SES2_9CHLR UspA domain protein OS=uncultured Chloroflexi bacterium GN=HGMM_F17E05C18 PE=4 SV=1 --PPQEVLICVGGIGYEVTAERIGLQLARHFQAHVTLFTVIPHADLDyplvhqvqeheqdlwetdtpigRALRRGLEQAHSLGL-EVAVKVRHGEVVEEILKEIRQHKPQLICMGSPFSSqSLRHYYMPNVTAEVAESGLAPVLTAR-- ->tr|A0A0C1KWP0|A0A0C1KWP0_9PSED Universal stress protein OS=Pseudomonas sp. C5pp GN=RR51_05970 PE=4 SV=1 -AMPANILVAVDVAKADLaqqalnhALVEAGRQLASPCNGQVHLLSVYDLPlamlanpdlaaPWAEQVRESLQLpfdelADIHGIPYAQRYFIEGAPLRVIQSLVPTLKVDVVVVGVVQPRRWAK-LIGDTTERLVNDAPCSVLAVRPP ->tr|A0A150XP44|A0A150XP44_9BACT Uncharacterized protein OS=Roseivirga ehrenbergii GN=MB14_15415 PE=3 SV=1 -FEVKNILIPTNLTDDYTAAMPDLLKFAESYNAKLTLVYVNTQAHFkttLQANKLKVEFLEKHGLENHAVEIFnAKSINRGILYAAEFFNSDMIALFSYHTENIKTLLVGNITEYLITKSKVPVLTLN-- ->tr|A0A150XBG0|A0A150XBG0_9BACT Uncharacterized protein OS=Roseivirga spongicola GN=AWW68_09685 PE=3 SV=1 -FAPNKILIPTNLEDDCSQRMSDLLALAEKFNSELQFVYVNTPAFFhtsPQIRKKSHLWFQRNGLKGYEIEVFnTKQLQKGILNAADFYESDMIALFSKHSESIKDLIKGNITEYLITRSDIPVMTFN-- ->tr|A0A1M4XRG6|A0A1M4XRG6_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfacinum infernum DSM 9756 GN=SAMN02745206_01092 PE=3 SV=1 --LDKCVLVAVDGSERCLQAVSRFASFLRgRKDCCFVLLHCVQQNLLLypgelwdaetslriakdtqekicrSITEPCRKALRETHFAeeqvETVCCFDSLDPGMDILRTAERHKIRTIAVGRRGLTPAENLLLGSVSSRVAQYAEhRTVWVMDP- ->tr|A0A1N6L1Y7|A0A1N6L1Y7_9BRAD Nucleotide-binding universal stress protein, UspA family OS=Bradyrhizobium erythrophlei GN=SAMN05443247_09407 PE=4 SV=1 --AFKEIVIAWDHTAPAARAVGDALPLLTNAT-QVRIVTATDRVTDaqRGSGAALRRHLAEHSIEARLDTIRIEgsSVGKVFEAYIDQNAIDLLVMGGYRHSPVNEWFWGGMTNTIINDPPCWVFL---- ->tr|A0A0S8FD65|A0A0S8FD65_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium SG8_31 GN=AMJ59_16185 PE=4 SV=1 -WPPKKLLVGLDPVHDGSVLVERAAELGRRFGATIILFDCVQNQYVSrryfrdghalnharqtlvkghrDRLERLAQRMIVGNL-SVIVDATWDAPLdDGLIRAASRHDADWILVGIGYHRIPRLPFLASTDGSLIRQATCPLLLVQQ- ->tr|A0A0C5V4K3|A0A0C5V4K3_9GAMM Universal stress protein UspA and related nucleotide-binding protein OS=Gynuella sunshinyii YC6258 GN=YC6258_02377 PE=4 SV=1 -FRINNVVVLIDPAEDNQSALKKAQIITTTVNGKLTLFASGYNSTLAnhsnvnpensekakaaflqrirANLEEKADTIRQEGL-SIECVAVWDKHPsQAIIKYLETNSVDLVIKNTHHQNVMQRTFFSHTDWDLIRYSPAPLLLTKN- ->tr|W9V8E0|W9V8E0_9GAMM Universal stress protein E OS=Nitrincola nitratireducens GN=uspE PE=3 SV=1 -NSLSKILVNITQEQDKYLLPEKAIRLAQALSAKIEFFKCGYQPHYSsmnllgndileklqhnrlrdleGSLNELLATLKKDYD-NLSVDVAWDRGIaEGLLTKVERSNPDLVLHEVAEHPHLLHRLLVPHDWQILRECMAPLMLCKS- ->tr|A0A1N6PXZ9|A0A1N6PXZ9_9GAMM Universal stress protein E OS=Marinobacterium stanieri GN=SAMN05421647_102114 PE=3 SV=1 -ESYARFLVHLKQDEHRGELLVKLRKLLQA-DSQVELFSHHYSAAVEgstlfdpekhqhaiqsllrqieKGLQSHTDKLEQLGV-KAGADVSWGRDEaETLVRKVMRYKPDLVMHAPDTHPDLLQRILGAPEWRLLRLCPAPLLLSKK- ->tr|A0A1B8RW00|A0A1B8RW00_9RHOB Uncharacterized protein OS=Leisingera sp. JC1 GN=A9D60_23785 PE=4 SV=1 --PYRRILVALETGDTlVDEILSTAVEFSHEANSSIRFLTVVSHVPEEvsdiallpavdpnipldhrekiakaevaKAKSAGRHLLDSFePLGESKHVVRRGVLEDEIIKYATQWPADLLVMGAHNRSWFKKILSNPSSTRVLDGVGCAVLIVP-- ->tr|A0A1F2VER2|A0A1F2VER2_9BACT Uncharacterized protein (Fragment) OS=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_67_14b GN=A3J29_18280 PE=4 SV=1 --PFRRIMVCVDGSEMGETVVLHATMVAAAFGAPLTILHVLEteshgdtppsdPLDWGVRQRAARAYLDRlvslAGHIDVRAELIQGRAAEQICCWALQHGADLTVLASHGEHGRSEWTLSSTARKLVDGVPGSLMLIPAD ->tr|F2NEY0|F2NEY0_DESAR Uncharacterized protein OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_0433 PE=4 SV=1 ----MKILFAGDEHPYSAYALKEVIRLARNTWADVTMLAVAPGDKGvpksdhlliqalqgyrehflksseaegspyarkewrYEWLPLKNGVWEELlvcrgDKRDVRVCFRVGNIVQEIVAEAKDEETDLIIVGCTKGR--ECIWQDAAAvpQKVVNDADCSVLLVKEE ->tr|A0A1Q6DKL3|A0A1Q6DKL3_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium DB1 GN=BM485_10700 PE=4 SV=1 ----MRIIAAFDHHSYSERIIADLADIAANTWADITILGVQQADGGggpddyfagtfrhyreeflrrvsggelpyggvtgyEEYHSLGKGRWEINnqgwegdVRKKLLVRIRTGDPMKEILAESREQKSDLIILGCTKGL--DCQWQGEVDlpRKIAAKAGCSVLVIKEM ->tr|A0A1S8WKA9|A0A1S8WKA9_9TREM Universal stress family protein (Fragment) OS=Opisthorchis viverrini GN=X801_09324 PE=4 SV=1 -SSARSVLIAVDDSPPSKNAFKYYMRWLSRSDDAVTLYYALEPSSLPsvpltnlgtiphdewskiihsklecvrRLESQYVTDLQTKGLNYQFVYETADQVGKSIVSKAEKYRARLVVMGSRGLGALQRTLMGSVSDYVLHNASTAVCVIPHN ->tr|E4U688|E4U688_OCEP5 UspA domain-containing protein OS=Oceanithermus profundus (strain DSM 14977 / NBRC 100410 / VKM B-2274 / 506) GN=Ocepr_0502 PE= -RPFKHFLVSTALADPSRRALEFAKKIADAVGARITLMHSVEPIAEppipihmpdpryieerQALIEQLAKQLHEFAAPyGARPLLKEAKPVDAICQVVAEEDIDAVFIGKSRQSRF----MGSVTREVLERAQVPVFVHP-- ->tr|Q12XP0|Q12XP0_METBU Universal Stress Protein-like protein OS=Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M) GN=Mbur_08 ---YKNILVPIDEKQLSKRVIDHALHVADKESGKLIIVYVERKKTLecifpkelakkmmvivkeniESNMEYALENAKISGIAVENIILDNDEIAKDLIRISEEKSVNLTVMGSES---LKARSPWEYhpmayrSRYRTCSCHHRRRLIHAF ->tr|E6VTX7|E6VTX7_DESAO UspA domain-containing protein OS=Desulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2) GN=Daes_0040 PE=4 SV=1 -------LVCVQETKRSQAMLDRAVRYAKACDCPSTLLSVAPDEAGresaQRAVNEADAYFREHGVTPHELLVEVGNPAEIITEIGY--DFSLIVMAESAKPWFAKTFS--VAHEVAARARNSVLIVK-- ->tr|M1WTF8|M1WTF8_PSEP2 UspA domain protein OS=Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN=BN4_12302 PE=4 SV=1 -------IVCVQDTDVCWKMLPKAIRYSITCDCPISLLAVAEDEEGkasaQKAVEKAAEMYRQAGMEPHELLVEIGDPADIITEIGY--DFSLIIMAESEKPWFAKVFS--VAHEVAAKARNSVLIIK-- ->tr|A0A1B7XDM5|A0A1B7XDM5_9DELT Uncharacterized protein OS=Halodesulfovibrio spirochaetisodalis GN=SP90_08160 PE=3 SV=1 --MYKKMLVAFDGARTSMDIVRQAAQFARSENSMVDIVTVCPEYQGDlrihgdtsvlydmyesirNALNEAVQQCEEIGVK-AQGHFCVGNPSDILVEQVGALGSDIVALGTHSSQLLQSIVVGSVAGTVVQQTASDLLIITGN ->tr|I5B460|I5B460_9DELT Universal stress protein UspA-like protein OS=Desulfobacter postgatei 2ac9 GN=DespoDRAFT_02417 PE=3 SV=1 -TDIKTIMACVDLSDYSPMTLGYTLGLAQQGDIKITICSVIPLREVtpvfmtgtiyhcREDTTEYLEELKENRKaeinalinklimercpqfsSKIDIRVSTGHPADAILDMVERINPDLVVMANKGRSNLSNFMFGSAAEYVFRYCTAPLLSVRD- ->tr|A0A0J1GRW3|A0A0J1GRW3_9GAMM Universal stress protein OS=Photobacterium aphoticum GN=ABT58_02935 PE=3 SV=1 -MNYKHVMLAVNLDDNAPFLVQKAAQEAKLHGALFSVIHIDPDFSAlyegvrefdasnetaeqSESVLAMTELLAGTDYPVHKHIFYAGYVEDQIIRAIETFEVDLLVIGHHE-STIFRQLTMSASEPLLRRMPCDIQFVKLE ->tr|S5DP01|S5DP01_9ACTN MedDCM-OCT-S31-C51-cds20 OS=Candidatus Actinomarina minuta PE=4 SV=1 -YPYKTIGLLINSNFDENSSNSIAFDLASAMSANLVAININQPKFLqqdnekqlAGTLEKLQDLALSHEV-QLDIETHEGNEAKIFSEQTS--KFDLSIVSSSAT---QTWQGRKIVEFVSKNSKCSVLYIP-- ->tr|A4Y6Q5|A4Y6Q5_SHEPC UspA domain protein OS=Shewanella putrefaciens (strain CN-32 / ATCC BAA-453) GN=Sputcn32_1915 PE=4 SV=1 -NKANTILMAVDLDASNpqkkslnDLVVEQAKMLANATGAELHLAHVIRVPPIlrdmdviniheviESAHQKHADKLKVLGLAPENIHLIAGDPELCLFELSCRLKSRYLVIGARQRQGLLGYVLGNTAEAILSRMRSNVLVVPKN ->tr|A8G0E4|A8G0E4_SHESH Uncharacterized protein OS=Shewanella sediminis (strain HAW-EB3) GN=Ssed_3963 PE=4 SV=1 -HRGNAILMAVDLGSDNvlkqqlnQAVISHGKALAKATGSKLHLAFVIRVPRVlrdmdlintstivKDAYQEHQKQLAKLNMDPECIHIIAGDPDLCLYELSCRLKARYLVLGARQRQGILGYVIGNMAESILSRTRSNVLIIPAD ->tr|E7QZL0|E7QZL0_9EURY UspA domain protein OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_21097 PE=4 SV=1 --MSETILLPLRNYRPWAEAVAGAAAAVESSDVTALLLHVFDEEERASTRAnidddgsmtvddlaarksgivAAREILQDAGV-SVEVRGREQveTTADSILTVSDEADVDRLYLYGRKRSPTGKAVFGSTLQRVLLNATVPVTVVPSN ->tr|A0A0W1RE08|A0A0W1RE08_9EURY Uncharacterized protein OS=Halobacteriaceae archaeon SB9 GN=AUR64_03730 PE=4 SV=1 --MSERVLVPASRFDPWARAVADTVTSMEAsATAVPHLVHVFDEIEWNSTVQqsdaatvpdpdelaerksaimAAATIFDDAGF-DYTVIGIESeTPSRALLDLVDEANIDRIYMYGRKRSPAGKTVFGSRLQTILANSPVPVIVLPAD ->tr|A0A1X7L5D7|A0A1X7L5D7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Dethiosulfovibrio salsuginis GN=SAMN06275492_1478 PE=4 SV=1 --SL-SLMNAMDFSNHAINAYEKLLELLSGEPNsfkKLTLVHIHDDKNLElllkvanaeqieplieiekKRLEKMKEEALRAGIESVNISMKKGIPTESILDLIEEEHTSLVVLGAQGQGASEKYRVGKNAYRIAQEAKCCVLIVP-- ->tr|L8JKF6|L8JKF6_9BACT Uncharacterized protein OS=Fulvivirga imtechensis AK7 GN=C900_05326 PE=3 SV=1 -SDYNTIILGLDTERDskdnFSQAAAYLNDLADSLGARIDIVNIVKPGTNDKVkiERKLIDFAARYGIKDHSVTIVESdDKEKGLINFARTHSAGLLAVFSHAEDGFFRIFRDNLSEELTMSSDVPVLTIN-- ->tr|A0A0D3LHX3|A0A0D3LHX3_9BACT Universal stress protein UspA-like protein OS=Flammeovirgaceae bacterium 311 GN=D770_16095 PE=3 SV=1 -TDIRNIVLATDMNDKAHNGLRHIKVLADRLRAHLHLVYVTKSGKIQQRRSDVETYARNQGLANYTIEAIEDsDIEDGIKRYAAKVGADLIAVITHGRNGLSAMLSHSVAEDVIREASVPVLTVN-- ->tr|A0A1R1IPA4|A0A1R1IPA4_9CAUL Uncharacterized protein OS=Brevundimonas sp. ZS04 GN=BJP32_00545 PE=4 SV=1 -SDQPVILVPLDGMADALPALSVAKVFSGLEHAAVRILHVAEQASAAEELAPRLGLAAEDLR-GASLETRSGEPAAAILAAAGDLLARLIVLCTHTAPGSPAGKVGGTALSVLRGASCPVILVNP- ->tr|A0A1F3RP01|A0A1F3RP01_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_16030 PE=4 SV=1 -ERFSMVYVPLDRNEASKQVIPLASALAEAADATLCFIHAATHNEAATDLLEHLHVTRGQIR-NAMFDQFPGRPEDVIPATVNQHPHSIIVMPMSAHPEGGIQELGPVSLAVIKKADCPVVFAPP- ->tr|D4YQK1|D4YQK1_9MICO Universal stress family protein OS=Brevibacterium mcbrellneri ATCC 49030 GN=HMPREF0183_2211 PE=4 SV=1 -----VVVVGVSDTSNSPKALAWAMDMVRARGGRLIAVRASTAGGGFnayasppttgrRPLEPEVAKLKADvisvlgaeavegPESVVDVHVFRGETSRVLRNVSK--NASLLVLDAPRNPVTQ----PLLAPRVVYNVDCPVVMMPPT ->tr|A0A062V7G2|A0A062V7G2_9EURY Universal stress protein UspA-like protein OS=Candidatus Methanoperedens nitroreducens GN=ANME2D_01773 PE=4 SV=1 ---GKSMLLPVASRELvTDELITLTSCLAKFYEHRVEIFHVVELqrwytlpwkelytmRhHGEEEMMPVAKVLREQGI-DVDVRAVISEsSINAIPKEAAIGRHSLALMRASRRGILKQVVYGNPIERMLSSILCDVLIWRP- ->tr|A0A1G0LBI3|A0A1G0LBI3_9DELT Uncharacterized protein OS=Geobacteraceae bacterium GWB2_52_12 GN=A2X80_04820 PE=4 SV=1 ---PRRILVPLGRIVAePAPRIRFIAALHASFHGGVILFHLAADtlPeSTPRDITLFRSELHRHHV-ATLERFATGHIGRGITAEAATGRNDLIVLGASERSILRQLFYGNPAGDVMHQPPCNAILFRA- ->tr|L0IFD4|L0IFD4_HALRX Amino acid transporter OS=Halovivax ruber (strain DSM 18193 / JCM 13892 / XH-70) GN=Halru_2090 PE=4 SV=1 -REFdtSRILLPTAGGPDSDLSADVARTLQRTNDADVELLYVVDDPsERDEGEAFLSAWAEEHGLSDAGRTIDTsGDVEEAIRRESS--DRTLLLIGATERGLLSRLVDRSLVYDVVDEVECSVLLAERP ->tr|V5A6V2|V5A6V2_9ARCH Amino acid/polyamine/organocation transporter, APC superfamily OS=uncultured archaeon A07HR60 GN=A07HR60_01332 PE=4 SV=1 -PE-dsiGTPVALAGPGPHAPAAAERAAEFAEVNDSTPVLLNVQSPGhsaglsAEERGHRAIEWIADRAGLESDrydAEVVVAd-DTEAAIVEAVQ--AHGTVCVGLSEKSDNSRILFGSIAERISQTRAGNVGIIRGA ->tr|L0AMJ0|L0AMJ0_NATGS Amino acid permease-associated protein OS=Natronobacterium gregoryi (strain ATCC 43098 / DSM 3393 / CCM 3738 / CIP 104747 / JCM -DGFddaDEIAVVANRGAYDPLKLLFADAVAEETGAELNLLQAIAADapetQRETIERYHEELFSLLTVPARSTVIETDDEIAGLTRFVG--DADLLVTG-VDRTGMSARFLGRPGNRLVERVDTTAVMVQTR ->tr|A0A0E3LNZ5|A0A0E3LNZ5_METBA Amino acid permease OS=Methanosarcina barkeri MS GN=MSBRM_2633 PE=4 SV=1 -HLPdsiHKILVGY-NGKEnSVYGLSLAEKLAVNTGAGIEIISIISPDesqeNRQKITDELESLVGkISSIPVSFRVLTKYSIEDALLEASN--NNDLTIIG-DSSERFKISLLGTLSQRIARHSKKPIVIVKKS ->tr|L9WU80|L9WU80_9EURY Amino acid permease OS=Natronolimnobius innermongolicus JCM 12255 GN=C493_15308 PE=4 SV=1 -RGTaeiDDIVVATETGPYDRAEVELADAIATVTGASLTLVKAVPDDaseeAVASARGYLDELTAVLSSPAETELLRTADVDAALVDRAD--RTDLLVMGAPTHPDRVSAFFGRTTDAVVAETETSVLVVKEP ->tr|A0A133ULK7|A0A133ULK7_9EURY Amino acid transporter OS=candidate divison MSBL1 archaeon SCGC-AAA259I07 GN=AKJ36_01545 PE=4 SV=1 -GREkiGRVLALVGEGPNAPLAVRRAHELDKkAGVGELTIVNVQKGEkeeeeLQNQGMRMIEKTTNKARLESSeykSKVIIGe-DVEKAILKEVQ--NYDTICIGGTEHSVLSHTIFGSLPEKIGETAEGSVVMVKGY ->tr|M1Y0T9|M1Y0T9_NATM8 Transport protein (Probable substrate cationic amino acids) OS=Natronomonas moolapensis (strain DSM 18674 / JCM 14361 / 8.8.11) -LHYdtaSHIGVVTDEGPFDPPKVGLTDALAMAVDGTVTFYFPMPVDapesRRNTVEDYLSELADLCEAPVETKIIEPGT-DDAMERAAR--ESDVLIVS-GVQRGLTDRLFGRasR---VTAGSKHGTL--VVY ->tr|A0A0W1RMB3|A0A0W1RMB3_9EURY Amino acid transporter OS=Haloferax sp. SB29 GN=AUR66_19010 PE=4 SV=1 -LGYdepKQVMLTGATSPYSPLAVSIAERVAAANRGTISIQNTTEESdepdLWEVIDEYRSDLAAVLSVPVRTETL----FTDGGR--RI--HPDVVVQP-SPDRGIRTAVHGTL--SSTPSHNCTTLTVYSH ->tr|Q2LGP0|Q2LGP0_9ZZZZ Amino acid transporter OS=uncultured prokaryote 2E01B PE=4 SV=1 -LGYdepDRVVLTGDGGPYPPLVVNVAAAVADANNGEISLWRGDRPAt-ADEAGDYRAELTDLLSVPVAPTPTEWEPRTDGGV--PA--EPDVVVHR-GPDLGLRGAVDSG---GARPAVGCTTITVYPH ->tr|A0A238XU53|A0A238XU53_HALVU Amino acid/polyamine/organocation transporter, APC superfamily OS=Halorubrum vacuolatum GN=SAMN06264855_1232 PE=4 SV=1 -RGFdpSHVLVPTAGGSDSDLSAEVARVLRDGRGSEIELLYVVDDEaKRAAGAEFLGRWAQEHDLGNANLSVDVdGDVEAAIARRSR--DSSMVIVGATERGLLSRLFSGSLVYDIVNEVDTSVLLCERP ->tr|A0A1Y3GB49|A0A1Y3GB49_9EURY Amino acid transporter fused to UspA-like domain OS=Methanonatronarchaeum thermophilum GN=AMET1_0294 PE=4 SV=1 -RGFnptkhNKILLPTrLSS--kIGLTLDLSSAIARKGNGFIELLRIINPRassnEIEKIKEFQKRSEKRIKEESSSRIIKSKDVTKALINESR--KFDLVVMSASQESALKGFLFGTIPNEVADKTDTSVLIVQEK ->tr|A0A1F8R3D7|A0A1F8R3D7_9CHLR Uncharacterized protein (Fragment) OS=Chloroflexi bacterium RBG_16_58_14 GN=A2W36_06660 PE=4 SV=1 ----MHLLLCTDGTPASAPATTFGAFLATSLRAKVTVLQAPAGHPWEHLAARAAEAvrdeLAEAGL-DCQVVSRSEFPRQAIVSQSAKGQYDIVVLGLLERGNWlRRWLRGPSTRRVLQQVATPVLVVPAD ->tr|A0A0R3TLP3|A0A0R3TLP3_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1 ----RKVLFPLDKSSKVRAAIEWFFSFGYRQSDSIIFVNIVHPKYSRgvinlesssfnpsedfkldfdevhEIEDEYKEFARKAGVKFSTTCIADTDIAGELNMLADQEKADLIVTTALG----------ESIYDLIGDTKIPVLIVPS- ->tr|A0A0T9KF37|A0A0T9KF37_MYCTX Universal stress protein family protein OS=Mycobacterium tuberculosis GN=ERS075342_01446 PE=3 SV=1 --RIARMTLAYRRRPDADGPLTAAAALAERLGAELRLLTLLIRPPGlaarfrapggvldrqlAQAEEDLRYAAGLLgRGTPVERRTAIGTDIAKTLGTVDMLHGEVLACLSGRDGPLRKVFLGESSGKILRAAPCPVLVLPHG ->tr|K9AEU4|K9AEU4_9MICO Uncharacterized protein OS=Brevibacterium casei S18 GN=C272_13528 PE=4 SV=1 --KLKRITAAYSGSSTSADLILGAAMVSAESGIPFRIASFAPRSRVlsaasigrdveagivdewtRVVRRDTDRILCSIdeldiRPGETEVAIGTGPSWAAALTSIGWEDPEVMMLGSSGLGTLKRVSLGSHATRILQNSPVPVVVVPRR ->tr|A0A0B2B7V3|A0A0B2B7V3_9ACTN Uncharacterized protein OS=Mumia flava GN=LK11_47290 PE=4 SV=1 --RVERLVLGLDAEPSDEGAVEGALALARWLGASIALVTFGVRRLPalpfgggrradaevfavwrEDVERVHAEAAERIaaaGVEVGEQVVAVADSWRRVAERFRWEEGDLLVLGSSHEGPVERVFLGSTAARIAGHVPVGVVALPRR ->tr|A0A142H9M0|A0A142H9M0_9BACT Uncharacterized protein OS=Hymenobacter sp. PAMC 26554 GN=A0257_23110 PE=4 SV=1 --APRRILLAADREAFALAPAAlALRELLALPGTELFVAHVSGGVEDDAGCAAALRAVQDSGLVAglpipKLRGYNQDDYAEGVLDAVRDTQADLVVVFARQRSYLGELFHHSVTARLLADCPVPILVLPTT ->tr|A0A1G1T781|A0A1G1T781_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8648 GN=BEN48_12345 PE=4 SV=1 --PPRRVLIAADRESFALAPEAeVLRPLLALPGVEVVVAHISSGVEDDEGCALALRAVQASGLVEglpvpELRGYQHENYAQGVLAAALDTRADLVVVMARQRSYLSDLFHRSITAQLLQSCPVPVLVLPTA ->tr|A0A1G1TDA6|A0A1G1TDA6_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8648 GN=BEN48_07855 PE=4 SV=1 --VPRRLLLAVDGAPFDLHPLPdHVRQLLASPQATLDAVFIPDGKPARPDAITVLSTIRLDDAVPamplsRLHVHHAPDVAAGILAEAKRLRADMLVVVARQHSLVGSLFHSSITARLLEQSPIPVLALPAR ->tr|A0A1E4AFE0|A0A1E4AFE0_9RHIZ Uncharacterized protein OS=Devosia sp. SCN 66-27 GN=ABS47_13820 PE=3 SV=1 ----MKIVAFVDSSLYAHSVIDHTIWLALERRASVELVHIVSPNEVAasniapihpggavllerddtlnaklaelerqgrERLEQAHRALNQAGVNDVQVRLCEGHTAQTMVQATQ--SASIAIVGKRGEHaDLARLPLGANLERLVRGSKVPVLAVSRS ->tr|A0A1M3KL28|A0A1M3KL28_9RHIZ Uncharacterized protein OS=Devosia sp. 66-22 GN=BGO81_05390 PE=4 SV=1 -RPLASWLLAVGKDNEVSRGLDDLVQSRMLEALPGEVVHVGELTELiRSDLESIGLRLTHAGHR-VSITVLDGEPVRAVAERLATAESQLVVVGKFGRSRVLPMIFGDGVArDLTKVNQGPVLVL--- ->tr|A0A0S7ZP89|A0A0S7ZP89_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium SG8_11 GN=AMJ53_16945 PE=4 SV=1 ---MPGIICAVRGGPSSQPTIHRAITLAQEVGQPIHFLYVVNLDFLERtatsrthtitkelrqmgdfILLTVQAQAQSQGVV-ADGSIREGNVSEEIIHLCQETKADYIVLGSPEGDRednaFTQEHLNQFAQLIEDTSGAKAILVEGT ->tr|A0A1C2JD64|A0A1C2JD64_ACITH Universal stress protein OS=Acidithiobacillus thiooxidans GN=A6M23_18315 PE=4 SV=1 -MSDPVLLTAIDGSQNALLAAAVAARFSRLLGARLGLVTSLHVAKDplgfggglfsrdltdrllaearleaESNLRAVAERIEEHCDIgLPEYFLLEGDPEQEIPHLVQsLPETIMVVVGQRGFGTESKprglpHLLGGLGAKLSLALAVPVLLVPPD ->tr|A9AW06|A9AW06_HERA2 UspA domain protein OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_0596 PE=4 SV=1 -MKPFNLMIYLDGSSAARRMVAYLAPLARKSHVKTTFLVDEAHQDEAEMYFfNAEQLLQSDQAP--TRTIRGATPERAIVLETRASQPDLVAFGPLRKEGWRRWLGQSAIGSLARRLTCSMLLMQG- ->tr|A0A1H1UYQ3|A0A1H1UYQ3_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Gillisia sp. Hel1_33_143 GN=SAMN04487764_3031 PE=4 SV=1 ---MNKIVCATDFTRNSIAALQYAFKMSNLLKKELIVLNICNPEEDdeyhsasdnQAILDTRVQLLQEYCSihlkanfdsLQIRAIIKKGkNIPKKICNFIKDLDIAFLIMGTHGNSPFKAKNFGSITNAMIAASTFPILAIPPT ->tr|A0A1W9UJQ0|A0A1W9UJQ0_9DELT Uncharacterized protein OS=Desulfobacteraceae bacterium 4572_35.2 GN=B6I37_08745 PE=4 SV=1 -CPVSKVLIPVDGSAYALAAVHEAAALSSQLGtniASITLLRVVDiskhrektaelDQDADRILSEARQILLDAGIDeqKIVSRAHYGTPADSILALSVETDANLIMIGRRGRSASKELLMGSVSSAVLHRCGGSTVAIISS ->tr|A0A1G0ZW29|A0A1G0ZW29_9BACT Uncharacterized protein OS=Lentisphaerae bacterium RIFOXYC12_FULL_60_16 GN=A2498_01365 PE=4 SV=1 -RVFHRVWVPVAGGRNSAFAFEVATMLADPADGVIVVLNVRsGGeSITFDLEPFIDEQASRLNFPRERVVSRTvesRRVADTVVEEIERagDRCDLVVLGASPRSLFNPFTRESMPNLVARRCTKPMAIVNRV ->tr|A0A1Q7KHX9|A0A1Q7KHX9_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon 13_1_40CM_3_50_5 GN=AUJ08_00300 PE=4 SV=1 -VDKKNMVVVYDGREHSELVLKATS-------wlehsGRfkVNLLSISkGGGEKNSV-AMQQDFLSQLGVELKETqltASSSrsaDIVLSA--ISSF--QPDLVVMGATLGGFSVFnnPDFLALLDQ----LNCPVIIARGF ->tr|G2HBX5|G2HBX5_9DELT Uncharacterized protein OS=Desulfovibrio sp. A2 GN=DA2_3282 PE=4 SV=1 ----SNVLLCVDGSGENLRMADHVGfMLATPgaENHTVTLLHCREPEngagrgatgahgpvgphgladgplPGEEAIAAAREAVLANGVDesRVRVLMVRAsdrtgrtdrsDKAETILRVAEQDRFAVVAVGRRTalpDTLMRRMFGRSVSERLHDRVNRFSLWV--- ->tr|C0QL51|C0QL51_DESAH Putative universal stress protein UspA OS=Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) GN=HRM2_10250 PE ----KNVLLYLDGSESCLRMADHVGfILSHENRHRLDILTCEKSSDITRAVEKCKSMLLDYGFPadLVRHKSVITdNVAGAILDGVNDEQYAAVALGRSGtkRNLLQRLFKGPVCSILFKELNETALWI--- ->tr|A0A1V0DC09|A0A1V0DC09_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium RA GN=AWN76_004780 PE=3 SV=1 -RPIRRVLLACDGSAPSIQTMQRFAQLQPfGTDLTVDLVHIREDTGEAArhradlLLHRTRTYLEAHGFQTLNETSMEGdHTAERLLRHAEHHEADLIVAGAHSVSAVRRIAFGSTTHALLDQSTIPLFLYH-- ->tr|A0A024M608|A0A024M608_9MYCO Universal stress protein family protein OS=Mycobacterium farcinogenes GN=BN975_04534 PE=3 SV=1 ----MTILAAFSASRHSSAPLNLAVQLARTTGEQVIAAAVVERSWPprddpveseyvayvraqaTQALQRAVAVL--PVDLDVTSVVHEStSIPTGLIELADAHRVTLVTVGSSSSGMIGRVTLGSVTERLVHTARVPVAFAPRG ->tr|A0A0Q9DRF6|A0A0Q9DRF6_9MICO Uncharacterized protein OS=Microbacterium sp. Root280D1 GN=ASE34_04575 PE=4 SV=1 ----RGIVAGVKDDDLMTAIVGAAAGEARARQEPIELIHSSFSGVipatvetrATIAARVAAVESMVDAGTRVRTRYTQRPPAEALLDASR--NAALLVVGVGHPRG-AGHALGAVTHDVLVNIDAPVLVVRRS ->tr|A0A1V4QAC8|A0A1V4QAC8_9ACTN Universal stress protein UspA OS=Gordonia sp. i37 GN=B1964_07285 PE=4 SV=1 -MPSRKLLAAYLPTPGGEDALALGIALAGPFHAALDVCMVLPPPPQGgdggadpvrktteMLDAQAADWLSEAvgripDEVVAEGHIAFHeNAAEGLVAEAESTGSAAIIVGGSGGGIRGRHALGSVVNDLLHISTKPVVITPLG ->tr|A0A0C2N8E2|A0A0C2N8E2_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_01625 PE=4 SV=1 ----KKILFTVCEEPNSRQAFDYYATKIHERSNPIVLMNVVVPSFSFadgripplyhedkqsggvtqeklkkteDLLDGYLERCKELKLRctKETVILKHNKVSDEISSYAKG-KFDLIVMSGGKHSTFERIFLGSTTLNTIQKSSVPVMVIP-- ->tr|A0A0W0VR38|A0A0W0VR38_9GAMM Uncharacterized protein OS=Legionella londiniensis GN=Llon_0448 PE=4 SV=1 -QANARVAVAVDPNDEesegknlSLNLLEISHSLAKHFSGNLDIISCWHFPFEDylrdniwvkvpehelkkmiheekeRTMSQLKALMKEVNVSgeKHQIHLLKGKPEKQIPDFIDENKIDLLVMGTVARTGIKGFIIGNTAENILQELDCSLLALKPQ ->tr|E8RCR5|E8RCR5_DESPD UspA domain-containing protein OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1706 PE=4 SV=1 -RKEIRVAVAVNPGNRetaerdlSIRLLQHARSLADTCSGELDILSCWDFEFERylrgntrvdipedtmrntvqtaqtSHQAELNLVIEASGIGgSFEVHRLRGRAEKMIPFFVKSKHVDILVMGTVARTGIFGYLMGNTAENIMDELECALLALKPG ->tr|A0A1Z4VI32|A0A1Z4VI32_9CYAN UspA domain-containing protein OS=Raphidiopsis curvata NIES-932 GN=NIES932_26940 PE=3 SV=1 -KMIQKILLAVSGLGHAEEMMKNLKELPSIQSAKVTVLHVVPSQSTAaamtekweeggKILANAIQSLNFDPSQ-VSSILRQGDPKDVVCQVADEIGVDLIVMGSRGLKRLESILSNSVSQYVFQLSSRPMLLVKDD ->tr|A0A1F3RS21|A0A1F3RS21_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_15735 PE=3 SV=1 -GKWSRLLYPTDFGKHSERVFTRVIALARILKAEIMVYHEARSPRNiqarrrtiefntavdsvpsawvdswvarRTRMQEYVDRARKSGVIaNAFLDVGGLPLHEAILRAARKLNARLIATASFS-GPVKSAISGAVTKRVVNNSHCPVWILHEK ->tr|E8T453|E8T453_THEA1 Uncharacterized protein OS=Thermovibrio ammonificans (strain DSM 15698 / JCM 12110 / HB-1) GN=Theam_1419 PE=4 SV=1 -MLFQKVLYPFDMRKSSLSVKPYILKLKEAGCKEVHMLYVLIPSDWgllprdeydceeklevlkgaldegygdavvriYRRMKEVAKEFEEAGI-SVRVVLVPGELDETIAEYAKKHNISLVTLGITSES-LSFFRVGR-LLDIIKEVQQPVLIVKA- ->tr|A0A1D2WLB6|A0A1D2WLB6_9EURY Uncharacterized protein OS=Methanobrevibacter sp. A27 GN=A9505_07740 PE=4 SV=1 --MYKKILVPTDGSEASFKEVISASNLLAE-DGEIIVLSVAKQLkqhplqikkdikktneTFIEYAKENVEEMKKKfdSNIKVSTKVVVGFPAEAICDVAEKEGVELIVISSAGERGFSKRIIGSVAGKVCSISNINVLLISNE ->tr|A0A101VY77|A0A101VY77_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium BRH_c36 GN=APF80_03725 PE=4 SV=1 -----SIVVCFDGSEESHRALRYAVRIGSGTDADLTLLYVRPFDqglrtsgldlsvvrenilswgldlPGMRVLKEGRDALVELGWldseweqehahaqvrgdplgdnaivysspsgRSVVLRLLVAqSVADGVLDECELGQYNLCIVGWPASGGASgvGYITHEIATRIAREHTGTVLVSR-- ->tr|A0A1Q2M890|A0A1Q2M890_9GAMM Universal stress protein OS=Microbulbifer agarilyticus GN=Mag101_15435 PE=4 SV=1 ----KVVLATVNYQAqttqqrqLNRQITERASYIAEVYGAELHLVNAFLDSMLYPDRGALAKLASKTGVPTDRIHVKQGYTNEVVAEIAKEINAELVVMGTLNQYGETGSlLRGNTAERVIGSLDIDVMVCNA- ->tr|A0A0C2FBT6|A0A0C2FBT6_9ACTN Universal stress protein UspA OS=Streptomonospora alba GN=LP52_24045 PE=3 SV=1 -DSFRRAMVCLDHGARDDTGIALAQSWADQLKLELELVHVASTEDDveasEERTARIADRMADGGASVGHTQLRGSAPAEEVAKLLSRHPGSIAVLANRGRVGIARSILGSVSSRLLETSPAPLVLTRVP ->tr|A0A1W9HFZ8|A0A1W9HFZ8_9PROT Uncharacterized protein OS=Proteobacteria bacterium SG_bin7 GN=A4S09_05410 PE=3 SV=1 --RFQNVIYPTDLSSHSQKTLNAFLPVAKLMNAKIHLLHGLQGSMtnAtlayeglsdvafnfytqemkrikksrEKQIGAWAKICKSHGVNtTTEIAEDQTQVLDTVLKVAKRKKANLIAMATTS-GPFENLMTGGITRQVVRYADIPVWIMH-- ->tr|A0A0C1LMH3|A0A0C1LMH3_9BACT Uncharacterized protein OS=Flavihumibacter solisilvae GN=OI18_01870 PE=3 SV=1 ---MANILVPFDFSVNATTALDQACLVAVKKRLSIEVLHIVNFKTASEypadwgvdphspdlhmirkklnehVDERKRTCSAVEV--PIEISVKESVMVnGGIINHMLHKKSDLIMMGTHGTTNAIERFWGTNSSTMINHSLFPVMVVPPQ ->tr|A0A1M7IXT7|A0A1M7IXT7_9GAMM Universal stress protein family protein OS=Rhodanobacter sp. OK091 GN=SAMN05428972_3627 PE=3 SV=1 --SFEHVVIGCNGSIESIRAIHAALPFLRMAKHVTLVDGDVRSSndaDSCLPHFDPFVYLLRHRITAKPQYIRasSDLAGDILLKKARNAQVDLLVMGAYSRSPARERVFGGATRRVLEEADIPVLMQH-- ->tr|A0A1F8NKU9|A0A1F8NKU9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_47_49 GN=A2Y53_00170 PE=4 SV=1 ------LLICTDGSSGSILSADLVSKLKFPTNIQITVLGVSENKsdldNIVASMDLIDKKFG-TTYV-VDRRIRNGKPIEEIMSEVLESKYDLVVVGGGRGQLDLlHPQLGSTTSKLARKLHTHFLVARN- ->tr|U1NXK6|U1NXK6_9EURY Universal stress protein UspA related nucleotide-binding protein OS=halophilic archaeon J07HX64 GN=J07HX64_00610 PE=4 SV=1 ---FQRMLYATDFSANAEQPFE-AFRYLRHASEEATLVHVETPRDPgretgnsQERLTDLATQLEAWDI-ETRTDLRQGDPTEGILAAESEHNPTTTLIGSRGHSRLRRLLLGNVSEDVVAQATGDVVLVPPE ->tr|A0A075TTI2|A0A075TTI2_9CORY Uncharacterized protein OS=Corynebacterium atypicum GN=CATYP_10235 PE=4 SV=1 -----RILVSFRADSl-THDAVEIAAWLARTdfPPVRVRALSTFVRPWPatslkklggkyvdwfrreaRAAEKRVKAAFTDAGIPekfwddp-VAVFADGPSEHALITAAADKFGADIIAVESDDAAEKGRLKVSNTADALLHSSPRPVCLAPRK ->tr|F8E3G8|F8E3G8_CORRG Universal stress protein OS=Corynebacterium resistens (strain DSM 45100 / JCM 12819 / GTC 2026) GN=uspA3 PE=4 SV=1 -----RVLMAWRPQSTSDEAAEVAAWVGRTEEIRVRAATVIPRAWEiqpgaqefqeyrnwvmaetQACMNAALSALGKAGLPqgmlaeeDPAVVDIAPTETKVLIKAAEDFEADFLLLGSHPAAPRSRFRMGSTADALLHCAPLPVLLAPRS ->tr|K1YIB3|K1YIB3_9ZZZZ UspA protein (Fragment) OS=groundwater metagenome GN=ACD_73C00108G0001 PE=4 SV=1 ---IRKIFVPIDGSEGSLEALSIAMKLAHQMKAEVQPVSISEFAYVpslsyvdpksynqdllkrRKKEIDFCLKKMSVDDKVLPAIVKMGNAAHDLPLLVKKTKSDLVVMSTHSRKGLVFTLLGKVAAHMIHHSPSSVFL---- ->tr|U2FI96|U2FI96_9PROT Uncharacterized protein OS=Campylobacter concisus ATCC 51561 GN=ATCC51561_1301 PE=3 SV=1 ----DNILVSWTGTTQSSRALTGAIDLLKSAK-KVQCITSKASLGDNaeLNLKKLEEYFKVHNISaSFEVIATTTIPGEALLKAANDRNADLIVASRYGENGLMEMVLGGTSRFFLEHTNIPVYL---- ->tr|A0A1F8T8N3|A0A1F8T8N3_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_19FT_COMBO_62_14 GN=A2Z37_08365 PE=4 SV=1 -DQVRRILICTGAELPSMETLRVGGQLASHGSAELTLLHVMSQIALQpestadelfasaegamesgtregLHFKEAIRILRDMGV-TakITPRLRHGLVVDEILSELDEGDYDLLAIGAHRRpGLtrWLEVMLDDVAEQLMSHAPCSVLVVRPA ->tr|G8T6W2|G8T6W2_NIAKG Uncharacterized protein OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_1596 PE=4 SV=1 -FVMSTVLVVTNFSDASHNALAYTCSLLQNTQAHLVLMNIYDFPGNMtgdaiaiaamseiiehdaALLEREFQWVQTNyPALQVDTEMVTGVFQEELQRKVIESNAVLVVMGAGG-NYTNLLSWDANIINSFIDLPVPMLVIPST ->tr|A0A0Q7VSJ2|A0A0Q7VSJ2_9BURK Universal stress protein OS=Duganella sp. Root1480D1 GN=ASD58_11425 PE=3 SV=1 -MGFKTVVVHVNSSAETERRVRLAAQIVRMSKGRLVGAAMSGISRLLyadhattmgvsmaaqcidearenarANLRRFETQCQMLDLPSFESRLLDDQAADGLVLQSR--YGDLVVLGQVNPDGPVSPLEEETPEYVAMNSARPVLVVPYA ->tr|A0A0Q6VVP8|A0A0Q6VVP8_9BURK Universal stress protein OS=Massilia sp. Root351 GN=ASD15_10515 PE=3 SV=1 -MTYRTILVHADLSRHAPQRIRFAATLARTFDAHLVGGAMTGVSRFLmpasiamggpmiaeqvdlmresaeRALAQFDTLADQTGAPSFERRLVRDEFDGGMALQAR--YADLVVLSQTDPDNPVPGDWNDLPEYVLLNAVRPVLLVPYA ->tr|A0A1F4JUA0|A0A1F4JUA0_9BURK Universal stress protein OS=Burkholderiales bacterium RIFCSPLOWO2_02_FULL_57_36 GN=A3I66_04740 PE=4 SV=1 -MSYKIILVHVDESRHAKARMEFAASMAMDADAHLIGGATTGMSREFiewigfdekaldldrlsdmlreraeQSLTQFEIIVRRTGVASFEKRLIEDDLSAGIAMQAR--FSDLVILTQSDPRDSASGVSGSFPETVVMESGAPALILPYV ->tr|A0A1E4ZYR7|A0A1E4ZYR7_9GAMM Uncharacterized protein OS=Chromatiales bacterium (ex Bugula neritina AB1) GN=AB833_13085 PE=3 SV=1 -MSYKAITTYIDDTPECEAWCEYAIDLALQHNARLVAVAARNLASHLiatdylalnsrwvselqeridknvsKIAALFERQCEKKGLTRAEVRVITGTPVDAMKHEAL--FSDLIVLGQYQKYQEqntngASLSRAGLQESLLMSSARPILYVPTQ ->tr|A0A1E3CYQ0|A0A1E3CYQ0_9RHOB Universal stress protein OS=Rhodobacter johrii GN=A9O63_04885 PE=3 SV=1 -MAYKSLLTVATSPERVEPAITVASRLALSGDAHLDVLALGIDGTQVayynmggtavvlqmaleraeqeaqAVEKAAAAALSAQPaMLRASVEsavAQMGGLAGLVALRSR--FADLVVQSRPYgKGRG--AESEAVVEAALFEGQAPVLVIPDD ->tr|A0A1E4NNL9|A0A1E4NNL9_9GAMM Uncharacterized protein OS=Rhodanobacter sp. SCN 66-43 GN=ABT18_04710 PE=3 SV=1 ---MKDILIHVRDFGKRTPAAHFGVRLAATLGASVTGVYACPRPLYIapaygpelmaeavnnarelvkdavQAKQSFLDWAASLGVSQSEWLVAEGPVGDALAQAAT--RHDLLVLDHAEDDRG---SAW-DIPGVILKTDVPCIVLPHH ->tr|A0A1Q4FA59|A0A1Q4FA59_9GAMM Uncharacterized protein OS=Xanthomonadales bacterium 63-13 GN=BGP25_04550 PE=4 SV=1 -MSEFDVVIHLRNCEIAGPAVEAGLALAKRLEAHVLGLHVVALSTAAfvspeavavqvnetshlleearARAPWWREELDRHGLQGEFQ-VVQGDAIDALCHASR--WSDLVITERPCANPD-APVGWGIASRTVFGSSAPVVVVPEG ->tr|T0RAW4|T0RAW4_9DELT Universal stress family protein OS=Bacteriovorax sp. Seq25_V GN=M900_1267 PE=4 SV=1 ---MEKAVIFATLETEVLEQLKKVKQHLDAEKSTVHIVHCHKIQMYInelsvftfpteneipqmteATNQVLEQFAKELGIKNYTVETLfDHDPKERCLNYLKDKNATLCVLGAKKKSGFETLFEGSFISYMNKFSPCDILTLRP- ->tr|A0A0W1SNR1|A0A0W1SNR1_9EURY Universal stress protein UspA OS=Haloferax sp. SB29 GN=AUR66_12555 PE=4 SV=1 ---FSRPLLPLANEDDAEVTCGVAFPRIAANDGTAFVVHVIEKAGGapdkagveqreevaDEVFDVAHRAADDVGV-DIDTELRFDtNVGDAILDAARDVDASAIVFTPRGGRSWWDLFSGDVRDRLIRKSDRPVVVLPHG ->tr|C7NMS5|C7NMS5_HALUD UspA domain protein OS=Halorhabdus utahensis (strain DSM 12940 / JCM 11049 / AX-2) GN=Huta_1212 PE=4 SV=1 ---FGRVVVPVASRDDAAATAAALAPYIDAPDRTVIAVHVIEKADGaldkasveqreadaEAMFGIVTEGLDGVDA-ALETEIRYGtDIAGTLVETADDVAASAIVFTPRGGSRWKQLLSGDVTHNLVHESDVPVVVLPDR ->tr|K7KAH2|K7KAH2_SOYBN Uncharacterized protein OS=Glycine max PE=4 SV=1 -FAGEKQNSTFQFLAssfrYGKGTNCWAVDNLINKGDQIILITVQPPQAHHTRKELFEDTssplvpleelrelnftkqyeIAGDPEAKAVAKVYWGDPREKLCNAVEDLHLDFLVVGSRGLGPIKRVLLGSVSNNVMTNASCPVTVVKGK ->tr|A0A0F6G8B0|A0A0F6G8B0_BURPE Universal stress family protein OS=Burkholderia pseudomallei MSHR2543 GN=BG16_3856 PE=4 SV=1 --MYRHFLVPVDDTDAGIDTVAYALEFARSIGARITFVQTRIEFeaadaarrigeterkeqtqrtddagksgecgrsdesvrpaptpdaaarpaaeatpaarAPELPIAKAEAAARAQGV-PCDSVRAAGATtADALAGAMLAHDCDLLCVGPALGDAAAAPPH-ACVADRLAARGIAVLTCAFR ->tr|A0A095YLL3|A0A095YLL3_9CORY Uncharacterized protein OS=Corynebacterium tuscaniense DNF00037 GN=HMPREF2129_04810 PE=4 SV=1 -KGITRVNFAFLDTKEaarsSTRGIGLAAALALTLDVELRIMAFSPEEtynfdddlthrplvdEWNEASLALLDRAWDVVMNvaqdlnikdphaelknfEVETRVSAGEGWCTVVDSQQWKKGDLLFVDSSPQSKTrsGYVHVGPHTAEFLSYAPVPVIVLRG- ->tr|A0A0B6TQ15|A0A0B6TQ15_9CORY Universal stress protein OS=Corynebacterium marinum DSM 44953 GN=uspA PE=4 SV=1 -RGVTRVNYAFLESEIdeNDPSLHFAAQLADSWGVDLRVLAFSPSGladqpfhdkfdfsrelvdEWREHSLAVLDRSHDVIADlfpdlAVESEIGSGKGWQGAIDALKWKKGDLLVLGSTPPGTLERVFVGSTATDFLRHVHVPVLIHPA- ->tr|A0A1X7IW16|A0A1X7IW16_9CORY Nucleotide-binding universal stress protein, UspA family OS=Corynebacterium pollutisoli GN=SAMN06295981_0990 PE=4 SV=1 -RGVTRVSYAFLETEIdeNDPSLHYAADLADTWEVDMRILAFSPSGiadqafhdkldfsrelidEWREHSLAVLDRSHDVVAEqhpdlSVESDIGSGTGWAGAIDALKWRKGDLLVLASTPPGPLERVFVGSTATEFLRHVHMPVIIHPT- ->tr|A0A1V5BMI4|A0A1V5BMI4_9FIRM Stress response protein NhaX OS=Pelotomaculum sp. PtaU1.Bin035 GN=nhaX PE=3 SV=1 --MFNKVLVVYDGSPEAKKALQDGLKLAKIAGAECHLVRVIKKPKHvsneafqqeaaseptlgQKELVGARFLASQAGF-DLPTHTILGDSCEVLKNFVQKGMYDLVVVTPKQDNTLKDVFFGGYVEKLLRNSDISVLVVK-- ->tr|A0A1L6I6B0|A0A1L6I6B0_9BURK Uncharacterized protein OS=Paraburkholderia sp. SOS3 GN=BTO02_28655 PE=4 SV=1 --PPHRFFVASDDSDASRVSVDEVARLMQ-AGDALRVARVVLDPVGAPPVDTLDSVVLQAAGH--------GNLAHAIVGAALEWRADLLVLGTHAGEPSGKWRFASIAEQVAQLGALPLLMVP-- ->tr|F8C3X0|F8C3X0_THEGP UspA domain-containing protein OS=Thermodesulfobacterium geofontis (strain OPF15) GN=TOPB45_1619 PE=4 SV=1 -----HLLVCYDGTPSSTKIILYLKELFSNTPLELTLLKIISHPSasqgietdlykklqkeafleekakevflqAERELKEVSERLKEHLPAKIYTKVLfkYGDIAEGIINFSKENLFDAILVGRRGLSKIATYILGGVTHKLIVSSLIPVWLIRGD ->tr|A0A0U4N1Z4|A0A0U4N1Z4_9BACT Uncharacterized protein OS=Caldimicrobium thiodismutans GN=THC_0868 PE=4 SV=1 -----HFLLCYDECPACRNILTYLKHLFEGREIELSLLHVITIPTslllpqrdylreikreeeiekfcrenqerVRKRFEEIIQDLLKSLQVKAHFYIEfaESDRALALLQFLKDKNFDAVIAGKRGLGRLASIWAGSLTQKLILYTHQPLWIVRGK ->tr|N1WQ46|N1WQ46_9FLAO Universal stress protein OS=Psychroflexus gondwanensis ACAM 44 GN=pgond44_08827 PE=3 SV=1 -FPFKNIVFVSDFKEDISSVFEEVKKMAEKCHAKIHLLNINTTSDVnsvENGLQPIRDFLKDFSKpEDYAIHVYNEsSVLSGIEKFEESNEVDLIVMYTHSRKGLSSIFSNSIAESITNHSKKPVMTVH-- ->tr|K6VWB3|K6VWB3_9ACTN Putative major facilitator superfamily transporter OS=Gordonia rhizosphera NBRC 16068 GN=GORHZ_125_00830 PE=3 SV=1 ----SPVCFAYDGSDLADSAITRAAEYFD-YGRDAVVVCVWQPADVgfttgerhldpnnassvcgvaEQTAQRGADLAEKAGFRARGIAVEAAPTWRGILRAAAEHDASMIIIAPHRRTGILGHLQGSVAEAVAANASIPVLMMPSC ->tr|A0A1E7H2E5|A0A1E7H2E5_9DELT Uncharacterized protein OS=Desulfobacterales bacterium C00003106 GN=BA868_04670 PE=3 SV=1 ---FERILFTTDWSPTSLRALEYILGFKKLVK-ELDIVNVIYDKLTVRAIRELKKRLIEtrarclDEDIEAEYHLYAGETASEIILAAEEYDSTAIVMGLTHNQRFRDIFRGRPSCRVASRASLPTLIVP-- ->tr|A0A1F9AZN6|A0A1F9AZN6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_49_15 GN=A2V65_05540 PE=4 SV=1 ----SKIMASVDGSESSLKAVDHALYMIHSHpDAKLTLYHVKPMLkDYceidftktgettdnllemgdrrclADFYGHVRRKIKEYQMDEHRIEYvevdGKLSVGKTILSTAQHQGFGNLVIGRRGID--RSFYTGSVSNYIIKNGGdMAIWVVP-- ->tr|A0A076MWN7|A0A076MWN7_AMYME Universal stress protein family OS=Amycolatopsis methanolica 239 GN=AMETH_3063 PE=3 SV=1 -SAQDAIVAGIDGSDHSLRALRWAAANARRRHAPLHVVYAFAPLAGFygagmpvlqnaydelvraveRTLAEAVRTAREVAGDEVTITSEMPDEPAAPLLVSRSRGARMIVLGSSGAGGFTGMLAGSTTLGVSAHAHCSVVVVRG- ->tr|A0A1D2U069|A0A1D2U069_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCN 57-15 GN=ABS95_03165 PE=3 SV=1 ----RSILVPFDFSKTSVEILRGIVPFAKSTGASIHLLHVIEPSLSsddshgrlDDELADVSESMLKiwagrivRGEARTFASTRIGLVVDEVISRAASIGGDLIVVGADGYHSPRAITLRSAAERICRFAPCPTLIIPES ->tr|A0A1R4KR67|A0A1R4KR67_9SPHI Putative universal stress protein UspA OS=Sphingobacterium faecium PCAi_F2.5 GN=FM120_18125 PE=4 SV=1 ---METIIFLTDFSIAARHAFDQLLTIAKRTKINnVIIYHSLAYFNNkfyntgdfmlpppvidemeiedvKGKLRLLKQEFLTVsPVTEVSAHYDLLTVMDGVLRISENEKIDLIVVGLRGSDDGGKNSVGSTTVDLIESHAFNLLLVPE- ->tr|A0A1L9C479|A0A1L9C479_9EURY UspA domain protein OS=Methanohalophilus portucalensis FDF-1 GN=MPF_1138 PE=4 SV=1 --KFSKVMVPLDFSDNSSKILDVLWQMTDVIH-EVVFVHIIENTKNKPQLEhkkkESFDKLYEIGNDlekklVVNYVVKEGKPAKVLDELAEEMGITLIMITTHGTESLKDILLGSTAENLLRNTVKPILLIPAD ->tr|A0A1L3Q365|A0A1L3Q365_9EURY Universal stress protein OS=Methanohalophilus halophilus GN=BHR79_07110 PE=4 SV=1 --KFSKVMVPLDFSDNSNKILDMLRQMTDIIH-EVVLVHIIENAKNKTQLEnkkkESLEKLYEIGNDleknlVVNYVVKEGKPTKILDELAEEMDITLIMITTHGVESFKDILLGSTAENLLRSTAKPILLIPAD ->tr|B8KHM0|B8KHM0_9GAMM Putative universal stress protein OS=gamma proteobacterium NOR5-3 GN=NOR53_2249 PE=4 SV=1 ----------------AMTLAEAALGLAQTRGGNVHVVHAWLPYGAEllddadleltdserqvyrqqqrsdseQWFKRVVQRIESVADEplRVKAHLMESPAVPAVERMVKDTNAGLLVLGTVGTSANPGVLIGATTESILAGIGTPVLALKPP ->tr|A0A1F3RV15|A0A1F3RV15_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_01365 PE=4 SV=1 -KCISKILWPVDPYELESaiqkSAAEALNGFLAASQAELEPVYILNPRQLDlgldapeqwleqyrpvaeGALKSFLEGrvvsSLSGNPWKFKVLVQASasnsAAVKTLNHHVNATGAEMIFLGTHGRKGMPRLFLGSFAETLLLESKIPVLVVNSK ->tr|A0A1F3Y6S1|A0A1F3Y6S1_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 GN=A2603_16235 PE=4 SV=1 -QPIRKIVVAFEPSPESPenrlGS-ELATVFTS---------ELLAPDLKFvttvgkrdiepgetarqfaaKLIHS----LRQASAPIKSIEVIPTreglkDAVEALYDYAVRVNADLIIAPNHGRRGLSRLRRGSFVESLVMTSAIPVLTLGPR ->tr|A0A1V5S0R4|A0A1V5S0R4_9BACT Universal stress protein OS=Bacteroidetes bacterium ADurb.Bin302 GN=BWY47_01244 PE=3 SV=1 --KRKYILVPFDYSDYSIKASLLAFDLANKFNIEIIFLHAYQDEESnvseaannAKDFYDKEIKAGRLPDAAYSFILRKGVPEDEIKRFIRRDEPLVIIMGTRGKDRKINDLIGSVTAEVMDISEAPVFAVPES ->tr|T0DI51|T0DI51_9PROT Universal stress family protein OS=Bacteriovorax sp. BAL6_X GN=M902_2855 PE=4 SV=1 ---MNKLMICVDITDESINAYKNQLKDFdWNRWDEVHLVHGFETQVYADtfyfasyplegqmgdieksvsdlLLGLSNEIVAEDYKGKVLGKCLfASSAKVALKEYAEENKIDEMIIETRGKHGIAALFSSSFAEYMVGHAPCRLMILRE- ->tr|A0A0S7YUR7|A0A0S7YUR7_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_06330 PE=4 SV=1 -MAGKRLLLPQNFTPNDRKALDFVVdTFGQLEDVEVTLFHAYTPLPPvevshstvtdklrgnmsflqqqvqekEAGMEAIKAQLVEKGFAEASVRQvfrpRKKDIAGELLDLYGEKHFDCLVLNRKP-GKVSRFFTGSVSHKVL------------- ->tr|A0A1E4BB62|A0A1E4BB62_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium SCN 70-22 GN=ABS52_05570 PE=3 SV=1 --LTGPIIVATDGTASASAAIKAAALMADRTGAHVTVLAVLEPLPLvaadyglllppaetdearrQALAQRVRDQLSETvgARPNWDVQVRDGDPAAVIARMGREAKARMIIAGIGHHDLLDRMFGGETALHTLRLSRVPVLAVPPG ->tr|K9SAA1|K9SAA1_9CYAN Transporter, CPA2 family OS=Geitlerinema sp. PCC 7407 GN=GEI7407_2607 PE=4 SV=1 -QHPFTIVVPVSNPNTQKNLIEMAALLAKQAQGRIVPLAIALGHTQspteeltsaftqgQNLVQRAVELSREHGI-EAQPLVRiDNNVAQGVSLASLEQDAQLIVMGWGDQTSLRTWLFGNMIDNVLWASHCTVAVTR-- ->tr|Q4C0C2|Q4C0C2_CROWT UspA:Sodium/hydrogen exchanger OS=Crocosphaera watsonii WH 8501 GN=CwatDRAFT_2422 PE=4 SV=1 -NDHFTVLIPIYNPYTQRDLIEMGALLAKKESGIIVPVSIAAAHVHmddpqvdgnlkqsQILLDRAIEISQEFEV-SAQPIIRiDDDAAQGISRSAKEKNANLIIMGWSENTGLKARLFGTILDTVFWSSHCPVAVMR-- ->tr|A0A0W0ZCF7|A0A0W0ZCF7_9GAMM Na(+)/H(+) antiporter OS=Legionella steelei GN=Lste_3088 PE=4 SV=1 -PLFKRIITPVERNDFPDNVISFSARLARYGNGKLFILNIAeNEREIqekrerlr-------AGPMKDPDT-DIELINQiEKNISKIILNEVIESETSFIIMNWSLEEHKRGRIFSSNIDHVMWTSTVPVAAAL-- ->tr|A0A1D2U069|A0A1D2U069_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCN 57-15 GN=ABS95_03165 PE=3 SV=1 -SKWKHVLMPLDFSPASSLALKYAAAITIENRADLTVVHSARNWAGLPTHDRSLLSMREARRqqvqqwirgelnfqLPCKVTVRLGSSSlASILSEANQERSDLVVLPTRAGQWLQRFRMDSVTEGVLRHSPCPILSIQEN ->tr|W2UDX1|W2UDX1_9GAMM Universal stress protein E OS=Gammaproteobacteria bacterium MOLA455 GN=uspE_2 PE=4 SV=1 ---MKNMLVVLDGSSSDEHVLRQAIQLAATSGGNIHLFMTVYDSIEElnryvgfdnyqevkqAILDEAEVKLRRLTDkfgDHFTSTMHWGrRWHFHVISEAKKISADLVIKAVQRHSRIAEFLHTPEDWHLLRGASCPVWLVNDS ->tr|A0A1Y5FY46|A0A1Y5FY46_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 50_400_T64 GN=A9Q88_07905 PE=4 SV=1 ---MENILAVITHWDDAEAVLGEAEKLAARLHTGLEVLVPVHDQLGElskylnwqdfsqlqgEIVAAERTRLESLCAdKDYRLHVEWTtKVHATIVEKAQNYGAGLIVMMASHDPLLSVLIHTPDDWHLFRDTPCPVLAMVKD ->tr|A0A081T746|A0A081T746_9SPHN Universal stress protein UspA OS=Sphingobium lucknowense F2 GN=AL00_01970 PE=3 SV=1 --SFSRAVLGWKLGPEATRALHALIALVE-PAAAIDVVTAGMTLPEctreLGAHHEVRRHLTRHGLTaDSHWLVDDEHiEAQTLTEHAQKIGADLLAVGGFSHSKMRDIVLGSVTRDLVERSDLPTLIVG-- ->tr|A3TKL9|A3TKL9_9MICO Uncharacterized protein OS=Janibacter sp. HTCC2649 GN=JNB_02110 PE=3 SV=1 ------VVVGCDGSWDSFRAVDLAAREALGHGCRLTVLVVPRDDPPGsdePLSGYSA--AEDRGRsraqvtahlareralaaapdLGVDIV-VDAVDGPAVEALAQ--RAMMLVLGGRGRGGQRALSLSSPSDELVRHLRVPILIPGVR ->tr|K7YYK8|K7YYK8_BDEBC Universal stress protein OS=Bdellovibrio bacteriovorus str. Tiberius GN=Bdt_3123 PE=3 SV=1 -KKDLRIAIVTDLTKKCRASETYGVSLAKRLGAHVVLYHSVAETlrtveqymfaageatpsidtiyadikkDAQNSMEKKLERLRSKGI-SCEGFIEQEKTPlvDTFLAGPAG-HCDLICMGDESYGGLLGTLLGSNLRDMIAKSPVPVIVVR-- ->tr|A0A1V6C181|A0A1V6C181_9BACT Sensor protein KdpD OS=bacterium ADurb.Bin132 GN=kdpD PE=4 SV=1 ----PRLLVCVSPSPTSARLIRLAKQLAPGIDAEWYAIHVEERNAPdltsdaSETLASNLGLAEKLGGE--VVTTVGSNIADEVIRFAREKNIIIILIGYGPRQKFS-FNRKNLVNEVVRKSGnIHILVVTDS ->tr|A0A1W2G5L6|A0A1W2G5L6_9BACT Nucleotide-binding universal stress protein, UspA family OS=Reichenbachiella faecimaris GN=SAMN04488029_0298 PE=3 SV=1 -MKINTILVPMDYSPCAKNAFETALILAKKAQANIQVVSVSHMPHIhaevvgaasiiqpllqeyhEQLDQQFEELISSSNIEEVSVTNTkyNAPLHDAIYSCTIQNECDLIVTGTKSQQDWLTQLVGSNSMDMVERAKIPVLVIPE- ->tr|A0A0D2UED4|A0A0D2UED4_9PROT Uncharacterized protein OS=Skermanella aerolata KACC 11604 GN=N826_30575 PE=4 SV=1 ----EHVAVLWDGRRDTALAVRGAVSVLAIARQVTVLAAPERgsPDILRPAPFSIQDYLSGHGIQAELKRLDPEatLGFGAVLDSVVGHGADLLVAGAPEHALVPVHLGRPNRLDLLHRSPVPVLLAH-- ->tr|A4RXV5|A4RXV5_OSTLU Uncharacterized protein OS=Ostreococcus lucimarinus (strain CCE9901) GN=OSTLU_31831 PE=4 SV=1 ----FgcgrSICIAVDGAH-VKSLVHYVMREIMRKTDIVQIVHCAADENAStlarvsaeleEIREELKTFL-DDENQLDSVLLDfTGDIREKVLEHVDERmsSkaIDLLVIGNRTRRAvLSRNIIGSTAQYILQYAHVPVLMVPDA ->tr|A0A1M3PL91|A0A1M3PL91_9SPHN Uncharacterized protein OS=Sphingobium sp. 66-54 GN=BGP16_17465 PE=3 SV=1 --SYRRIVVPLDGSCWAESVLPMAARLAKAADAELLLAHVVPNPELTEirplepedlllrqhvverneatargYLARIRTNLEAMGLRARVCSTRGDDVRSALAQLIQSEAADLVVLSARGQGANhhHQMRYGSVASFLMAHCTVPMLILQSE ->tr|A0A0A1YLA9|A0A0A1YLA9_9PSED Universal stress protein UspA OS=Pseudomonas taeanensis MS-3 GN=TMS3_0113365 PE=4 SV=1 -KTIHRTLVVIDPLQSEAQILERAKSIADLTQSHLHLLTCNKKSDLSSHLLDMQEALIDQGFSVSAQQAWNGNPHKTIIAVQQEQGCSLVIKQHQPDNPLTKSFLSPDDWALLRYCPCPILIVKAA ->tr|J8UWZ9|J8UWZ9_PSEPU UspA domain-containing protein OS=Pseudomonas putida S11 GN=PPS11_22539 PE=4 SV=1 ----------MAQHQHDDLALTKAKQIADLTHAHLHLLLCAKPNGHSSYLKLMQEQLVQEGYDVSAQQAWHDNPCKTVFAVQQAEGCDLVIKQHRADSALKKGATHS------------------- ->tr|A0A1R1LLF4|A0A1R1LLF4_9GAMM Uncharacterized protein OS=Motiliproteus sp. MSK22-1 GN=BGP75_20880 PE=4 SV=1 -PFNNRLLIVLRAGHKEQPALNRGCLIASRLGAQIHLIADERprHQKHKDWLQSYVDQLTAEGFQAQEAVWGKGDLIDNVLAAVRKEAHGLVIKYSDRSRPLAEALYTPRDWKLLRYVSCPVLIVRQQ ->tr|A0A1V5RJD3|A0A1V5RJD3_9CHLR Universal stress protein E OS=Chloroflexi bacterium ADurb.Bin325 GN=uspE PE=4 SV=1 -MSGARYLVIVDPAATGHPAFDRALLAARDSRGHIHLFGFSShpPlaangesssdaqeryrSEALATLGELAAHAEAQGIGVSMELGSSADVRQEMVQAAARSRADMVFKYSSE---RTLAHRDPGDWLLMRLAPCPVLMVKNV ->tr|A0A0F7ST98|A0A0F7ST98_PHARH UspA OS=Phaffia rhodozyma PE=4 SV=1 -SgedEGMKIVLGYDTTVDALLAFNHVLNRmSLHPNDHVYMAQVLPLTSAsassslfsspqstpnthtaqavsyegahgdeddtnlstlsskdrelvilRRIRKATMEKLTTEGIKllskgcKVTPVIvHSEQPAKALCTLAERHDADLIVIGRRKLSKLHRvVGAGSVGNYCLLHGGCNVLIVQ-- ->tr|A0A0M2Z6R0|A0A0M2Z6R0_9ACTN MFS transporter OS=Streptomyces sp. MUSC119T GN=AAW13_12710 PE=4 SV=1 --GAGPVVVAVGNHGRAAAIVDAAARLARDTGSPLEVVHVQRTAVVEEqaadtesatearaAVTAHLDRLAAQGFAatgqVLDSVGDHAAAGRVLARHATEVHARAVAVGRSPRGPLAQFADGSLTTALARAASCTVVLVDPA ->tr|A0A0Q9S1K4|A0A0Q9S1K4_9ACTN MFS transporter OS=Nocardioides sp. Soil796 GN=ASH02_24720 PE=4 SV=1 --QHRPVVIAIAAAEDARDLVAAAAELARMTGSPIELVHVHETTIVEEfaidaadwgwerqALRRHIDWLTQHGSTasglLLHSVGDHAAAGRVLARHANNVDARTVAIGNSPHGAAVQFAEGSLTHALIASARCPVVHLRPG ->tr|A0A0M9ZRJ6|A0A0M9ZRJ6_9ACTN MFS transporter OS=Streptomyces sp. AS58 GN=ADL00_08675 PE=4 SV=1 --GPPPVIVAVGAHEGAAAIVDAAALLAEDSDSPLEVVHVRRTAVVEEqavdteteeraraAVTAHLDRLAAHGIAatgqILTSVGDHAAAGRVLARHAADVRARTVAIGRSPRGAVVQFADGSLTTALTHAAECTVVLVAPD ->tr|A0A066ZYG0|A0A066ZYG0_HYDMR Uncharacterized protein OS=Hydrogenovibrio marinus GN=EI16_03585 PE=4 SV=1 --KGKEKLLLVIFDKAEESLLDRAVEQAKSRKLFVHVAYIHTYDVFDEdiaepesyeasekLLKKALCHFEDKGVYaegeVVESS--KVRLYDSLEAILHKVQPGYLMLPKGMKDKVKTLA--------STRGGQSPFLVIQ- ->tr|A0A1H6DQV2|A0A1H6DQV2_9GAMM Predicted arabinose efflux permease, MFS family OS=Marinobacterium lutimaris GN=SAMN05444390_108111 PE=4 SV=1 --HKDELIVALAGDSTDNAVLERAIQVATQSRQPVRVLHVRTFEALAEgaldteslarseqLVSTARARLEQAGLSvsveVLEAA--AVHLTTRILEQIERLKPAGVILGRGPERTLAHILHGSLVDGLNRRAGEDIELMVVP ->tr|A0A0G3EIP4|A0A0G3EIP4_9BACT Putative amino acid permease YhdG OS=Verrucomicrobia bacterium L21-Fru-AB GN=yhdG_1 PE=4 SV=1 -----RIMLSVANPDNVLPLMRNTYRICQAREARVELIHMIPVSDYvplrdvPNFADEGREGIVEAmlyltQIFPVGTTIRYCrNIARGLVSAVRQHRADMLIMGWHGRPRRRLFSFGRTIDPVIERSPSRVVVMKN- ->tr|A0A1Q7KHX9|A0A1Q7KHX9_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon 13_1_40CM_3_50_5 GN=AUJ08_00300 PE=4 SV=1 -----RILIPYTPE-NPDRLIKYAIRIAKETAGEVNILRVITVPHQtplsagVAFADTAKRSFEPLekmldsETVPNHYLVRVShDTTEAILATIEEQKIDLLVTDFETLRHDKKLLTLTTCKVLAINAEDDALQLEP- ->tr|W1KYL5|W1KYL5_9SPHN Uncharacterized protein OS=Sphingobium chinhatense IP26 GN=M527_15240 PE=4 SV=1 -VMGGTIAVAWDGGREASRALRRSVPLLKQA-DRVILVMVPHGMGRSCDGVRAIRYLKDQGIRaDTQVVHTPGDASSAIVDAVTKMDANILVAGAFGHPRLHRFIFGGTTQYLLESKRRPPLFLSH- ->tr|A0A1V5IQR1|A0A1V5IQR1_9ACTN Putative amino acid permease YhdG OS=Actinobacteria bacterium ADurb.BinA094 GN=yhdG PE=4 SV=1 ---RARIMMtaavPTEprpapGDHAapggpaapggraAPagpaasggekpadsvRRRVEALPFGRRFASWQPRRGVGDEEEGeg-----------PGSGV-----------------CGPSEGGHD---------PAR-------------------------- ->tr|W5XW21|W5XW21_9CORY Universal stress protein OS=Corynebacterium casei LMG S-19264 GN=CCASEI_13035 PE=3 SV=1 -NNAQTMLIAYDGSDRAVRAMEYAARFL--QPGTVEILTAWEPVARQaarvvtrtglqqaamepeaveddpayeealAICREGVKVAEDLGLAgRAHLVESATTIASAIVDAADELDVDIIVTGTRALKGFRGWWNNSTAEHIVRHAGRPVFIVPPE ->tr|A0A0C1IAC0|A0A0C1IAC0_9BACT Uncharacterized protein OS=Flavihumibacter sp. ZG627 GN=HY58_08030 PE=4 SV=1 ---LKQILVVIDFSDTSRSVIENIIPIANEMDCDVHLLHIVKPsilpvlvnsqftiatrghyvaessNTLMQWQTSFISQVKKGRY--LFTHCVQGNEEKQIREYALRHHIDLVVLTHHRPYPWSKLLTRINIDRLAGRVQCPVLNMPDP ->tr|A0A162NMY5|A0A162NMY5_9BACT Uncharacterized protein OS=Flavihumibacter sp. CACIAM 22H1 GN=A1D16_05125 PE=4 SV=1 ---LKQILVVVDFSGKSRQILESIIPMANELKCDIHLLYISQPsvlpftinaqqviavksdqvawatSRMMALQGEFIHLMDKGRF--IYSHVAEGSMERTIRTFTMKHEIDLTILTYRRRFAWSKWLNRININRLTKKIQCPILNIPES ->tr|A0A0P7XUF8|A0A0P7XUF8_9SPHN Universal stress protein family protein OS=Porphyrobacter sp. HL-46 GN=HLUCCX21_07585 PE=3 SV=1 --MYRSLLIALDTQDEagARLMAARCATRLVSPECAVHLAYVRTPLPRSyrrempknweaNERAEAEQWLRNFaehaeiSASVAGIHSPVGSVAQEVTRLAAALGIEAICVTAHRM-DPGRFLLGTNTQAIVRDALCDVIVVRD- ->tr|B9XRL9|B9XRL9_PEDPL UspA domain protein OS=Pedosphaera parvula (strain Ellin514) GN=Cflav_PD0421 PE=4 SV=1 ------VLLPFDESPENDETVTLGISMAREMHAQLLLLHAVLLNLSpygpinlrkieaalcEEVIAQAEKTMLSAQEQGVSAIfaLEEGAPAAVINRAAARWQPDLIVMSAHQHDHFlSQIFRRRTIDKVIRHVKCPVLVLQTN ->tr|A0A1M5YCF2|A0A1M5YCF2_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfofustis glycolicus DSM 9705 GN=SAMN02745124_03851 PE=4 SV=1 -DGNRKVLIAVNGSDDSMTAVRYISESLPKRGSELTLYQVMSAIPEEfwdlerdpvwikkvevirsweveqkrrssAFMEQARAVFETSGFPadavSFKIGEQKEGIARDLISECKN-NYDVLVIGRGESAHDTNMPLGGVTSKLLANVSsTSVWMM--- ->tr|S7TE90|S7TE90_9DELT UspA domain-containing protein OS=Desulfovibrio alkalitolerans DSM 16529 GN=dsat_2374 PE=4 SV=1 ---FSRILAATDFSRESDHAVRYAAELAEGLEAKLRILHVVESPRPltDEAVGDIRRTLAAHYAKDVAgrpfeaFDVSSGEPRQTIVEHALDTEADLIVMAHRRAeNSVFEPEADSVLAYVSQNAACPTLSLNRS ->tr|A0A1V4AVS7|A0A1V4AVS7_9BACT Uncharacterized protein OS=Candidatus Brocadia caroliniensis GN=AYP45_04460 PE=3 SV=1 ----GKVVIAVDGSAASVAGFTSAIHFAKSFNLKLIAVSVFDPHYhrvafesianvlsqeagqifrfkeqetlheeiidkglakiYQNHLDTVSRMAGDAGV-ELDTILMDGKPYDKILRFLQKENPSTLILGRTGVHNTNGLDIGSTTENLLRLAPCNVLLAGGS ->tr|E1R5P3|E1R5P3_SPISS UspA domain protein OS=Spirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) GN=Spirs_1531 PE=3 SV=1 --AIERILFPYDRSRSAENALRYYINNFHETTDQLIMMTASEGNSEYDSYEQERRFLEEHGV-TPKMLFTEGSPVHEVLAAAKREKSDMIMIGSHGRNKIV------------------------- ->tr|A8V474|A8V474_9AQUI Uncharacterized protein (Fragment) OS=Hydrogenivirga sp. 128-5-R1-1 GN=HG1285_10310 PE=3 SV=1 --EIKNVVLFFDGREKSIHAVNYLNGLYKDLGLNSVKIvSVleedsvEMKNHIKDLLNTHAQFKYEAQF-F-------------------------------------------------------------- ->tr|A0A0G3EBC2|A0A0G3EBC2_9BACT Universal stress protein family protein OS=Kiritimatiella glycovorans GN=L21SP4_00519 PE=4 SV=1 --RLEHILCAVDFSRESERAFRTAWKLARRSGAELSCYHLYDTTRSYypfasfrepagsrrrrkrrfrSFLARFDLQKKTIPCTFEQQRDARENEAERLLRDAENKACDLVMVGAKGRPASVTSLLGNVTENLRRTDLnVPVMILPHV ->tr|A0A0D3HVJ0|A0A0D3HVJ0_9ORYZ Uncharacterized protein OS=Oryza barthii PE=4 SV=1 ----MTMVVGVDESEHSYYALQWTLRHFfataaggQPPQYRLVVVNAKPTAASAvglagpgaadvlpfveadlkkssmRVIEKARELCAQ--VSDALFEVLEGDARNVLCESVERHQAEMLVVGSHGYGAIKRHLQHDGMDLARMyilpplgswieksvtpagSPLCSSIYCT-- ->tr|A0A0B5H133|A0A0B5H133_9EURY Uncharacterized protein OS=Haloarcula sp. CBA1115 GN=SG26_17500 PE=4 SV=1 -SGISSVLVPIAEGTHSALGVVVGGALAMGADAPVDLFHVSETKDetavarASTLFETARSRLP-EAVTVDTWHLEAPDVAEAIINESA--HYNVTVMGKPTQSRLREFVTGSVTAAVTDESENAVLTVQRD ->tr|W7STA3|W7STA3_9PSEU Uncharacterized protein OS=Kutzneria sp. 744 GN=KUTG_02438 PE=3 SV=1 --ENRCVTAMVSGGVDDETVVAHAAAMATSHHSRMEVVHAEPPTAMDDCVFAEKVRIATLRLR-TTVTTVRTLPHEVIANSD---GSDLIVLGRGQSA-GRPSNPGVVTKTALHHAPCPVLVVHPA ->tr|A0A0Q4BAC1|A0A0Q4BAC1_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_00660 PE=3 SV=1 --LFQHLVLPMGARPEEMTKLQWVVSRTAGFHTHVHVLAEYYPDKGLtnklsSNLAFMKRLFDGQGIAyTVEQASKSGSFKVQLQEYAQKVGADLFMIVIYQSTTGIMPVLNTMDQEMIANSLnIPVLCLNP- ->tr|A0A1F3NHW3|A0A1F3NHW3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RBG_13_42_15 GN=A2Y71_14810 PE=4 SV=1 --VFRNIIVPITYRREVKECISWAHFCSRMFNTKFILVRAKYTDANFkrgveSNTYFLSKYFTTKNVRfEIKVADGENNFGDEIINHARQVEADAILVMTTRDIGFADYVLGPQEQYIIANIEkIPVICINP- ->tr|A0A1F3CYV6|A0A1F3CYV6_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWA2_32_17 GN=A2X08_08170 PE=4 SV=1 --KIVDIVVPFDIEEKSRIQLNWVVLLSKYFDSNINILKPFISNNFKnekmkKNMCFIRQILDEKNIVfGIRTSKRETKFNNAIYEFANEINADTIFIMSYQ---FKEFILKASK-----FGMkVPVLCINP- ->tr|A0A1J5BE82|A0A1J5BE82_9BACT Uncharacterized protein OS=Bacteroidetes bacterium CG2_30_32_10 GN=AUJ97_01515 PE=3 SV=1 --GYEKFVVPIDITANSIQKIKWAVRLALHFNSTIHLIYVDTK-IKYhqqiyKNVALVKELFEKKNINyIEKKVICtKNEFVNEVLTYSDQINADLLLIINEANKLVPSFMKVSAIEKIIFNIYkIPVMCIIP- ->tr|A0A1V6I757|A0A1V6I757_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin028 GN=BWX59_00601 PE=4 SV=1 --EYDRILIPIDQDNTARIKIQWIRYINTLFKSKVYMITYNVSDSYGqknisSNIRFAENLFEKELIDyEIEVLESSRNFADSIFTYANEVESDLIMLMSDKYRSYVK---QIKKAENLELYKkIPIMCVNK- ->tr|Q3Z8N3|Q3Z8N3_DEHM1 Universal stress protein family OS=Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195) GN=DET0674 PE=3 SV=1 ---FGNILLPLDGSLFSEACLKQVSVLARDFKSKLTLLVVIQPPcipsdrspsiqpswdeyyqalleelkqQAQAYLERLTGELRENGIETEFRMEVSDNIPETILSTAEDINASLISFTTHNRSGIEKWYYGSVAAGLIENSPRPMLLWRNS ->tr|M0PHV5|M0PHV5_9EURY UspA domain protein OS=Halorubrum kocurii JCM 14978 GN=C468_02345 PE=4 SV=1 -ERVESVLVALRGTVGVGRNTRLVTGLFADAGVDVTLYHALDegetRDDGESFLNGVKTDLVERGIAAdriETLVEDADASIDAIAGHGE--AHDVVVMGETD-PSVTTFVFGMPSEQVAERFLGPVLVVQRE ->tr|A0A1I3CWU3|A0A1I3CWU3_9EURY Uncharacterized protein OS=Halorubrum aquaticum GN=SAMN04488066_1337 PE=4 SV=1 -EGIDRILVPIPAVAEFSRLPAFVNVLCEDSTREVTLFHVAEgdegRARAESIVAETREGMIEAGLDAelvDTRVVEGEEHDEEILRLAD--EYDAVVMYQAE-SRLGDRIFGTLPDRIADRTGDPVIVVRRD ->tr|A0A238WGM9|A0A238WGM9_HALVU Uncharacterized protein OS=Halorubrum vacuolatum GN=SAMN06264855_10769 PE=4 SV=1 -PPpsgTTRGIVLVKPDADLERMVTTLGTLFGETGVELRLFHAVEdqderlSDSTEYMLRGMVDHLAALGIDRerlTWDQSTDRDRLDVILSEAA--EYDFIVLSETQ-PNLRERVFGTVQSQLATTTGKPLLTVRAR ->tr|A0A1Y3GI80|A0A1Y3GI80_9EURY Nucleotide-binding protein UspA family OS=Methanonatronarchaeum thermophilum GN=AMET1_0797 PE=4 SV=1 -PPQKNILLVYRYIENLEKAGALINQFGLGGSE-IGLMLV---EPDETTLDQGVSKLMKQGVKLeniKERIETDREDIVNEIENRsA--DYGLLMIGRVD-RDLKDLILGDISKKIKEATYGPVILIEGM ->tr|A0A0S9NMI1|A0A0S9NMI1_9CAUL Uncharacterized protein OS=Brevundimonas sp. Leaf280 GN=ASF31_04675 PE=4 SV=1 -MAIKSLLVSASGDPGRDARRNLACDLASAFDAHILGIGASALVSlpidpygvnamsgqlqqlyremAETDIRTSKARFSEivgRRAPQSIWLQAIDNPATVINTAAK--AADLVLVAAHG---VGAPSRAPRAVDVVTGCGRPVLVVPKT ->tr|A0A170PSA4|A0A170PSA4_9ZZZZ Universal stress protein UspA and related nucleotide-binding proteins OS=hydrothermal vent metagenome GN=MGWOODY_XGa1796 PE=4 S -IRHYTILLPFNNAQPTATVLDAARQMAGPQ-GYVEGAFC-R-QMlpiiagegitlpgdylaefeeeGRQQAEAGRLKYLElleakdiplgdleASGLRAGWTEMVGSGPEGIGEYAR--LFDLVILGRSIGDSA--VDWKTTAEAVMFDSGRPLLIVSDE ->tr|C3KMY4|C3KMY4_SINFN UspA-like protein OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234) GN=NGR_b00860 PE=3 SV=1 --MIKVVLVRLDGTSGDEFRLAASESLAKLFDSHLVGLILNTLPEpalaesgvsvefwtrllqqaRERGKELESDLRSRlraisPSAELRRFDVYAHEQARVASRESR--AADVFLALRLSDADK-TVELHDVVEEILFESGRHLFLVADQ ->tr|A0A126RLI2|A0A126RLI2_9SPHN Universal stress protein family protein OS=Sphingobium sp. TKS GN=K426_09755 PE=4 SV=1 -MSYARLMVHLELGKSNAALLTVAGDLAERSHASLVGIAAAQPLVatpyagafisgeaieldraeIEREAKVAQSEFQTilsGRVADLEWRCMETTalLSDYLASEAR--SVDVIVTAPDRGGGLLPDTRRTSVGDLVMRAGRPVIIVPTH ->tr|A0A090GE88|A0A090GE88_9RHIZ UspA domain-containing protein OS=Mesorhizobium sp. ORS3359 GN=MPLA_1360076 PE=4 SV=1 -MSYKSILLSLNIDGPIEPITRIGVNLAKRFDARLIGFCAADAPLpvtmapegaaiaadvweqsrdeIRRRLTSLNGEFDGlva-GAVKTDWHGDIENPNHAVARRAR--MADIVVTSASQGASTGDSYRTVDPGSLVLRAGRPVLVAAQG ->tr|A0A0Q6YXS6|A0A0Q6YXS6_9BRAD Uncharacterized protein OS=Afipia sp. Root123D2 GN=ASC80_10400 PE=4 SV=1 -MAYKSIMVFLGLEQVNEAALRVSCDLADRFDSRIIGVTSGVPYVpvhlngmvaasmleadydeLALATARCESRFRDaikPCGQPFVWRESTEMPADFLAAEAC--SADVVIAELSENSPLMSGQRWLDFGDALMKAGRPFIIVPPR ->tr|A0A160UVI7|A0A160UVI7_9BRAD Universal stress protein family tandem domain CDS OS=Bradyrhizobium sp. G22 GN=BN2626_G22_4168 PE=4 SV=1 -MFFANVMVYVDPEQQEEGQIAVAESIARGFGASILGISAVAIEPpfvaegviieqttaedlerIRARLSAKEAWFRRivrLPSEKVEWRSAIAFPTEFLVEQAR--AADLIVVKRKQ--LWTNHPRYLDSAGAMLRMGRPTLSVPDG ->tr|N0B1I5|N0B1I5_9RHIZ UspA domain-containing protein OS=Hyphomicrobium denitrificans 1NES1 GN=HYPDE_25668 PE=4 SV=1 -------MLSLNDEPRVPNLVSAALSL-MGDNAHIIGLYAMPAV-vppqeiigagdrswldeqlraFEEQAGRVKNKFEGlfkDRPATHEWRFDnssfDATVADSVIEHGR--AADLIVTSRASRNGW----IDDVAERAAIESGRPVIVLPEE ->tr|B4RIM5|B4RIM5_PHEZH Universal stress protein UspA OS=Phenylobacterium zucineum (strain HLK1) GN=PHZ_p0257 PE=4 SV=1 -MTYADIVVDATPSPTVRQTLEVAAEFAEAYGGSLSV--------aafawprastlneallgnaggsalqalaFGEVLESTQAIHGEvfaDRQVVTDWCSGISDPNLILNEHLL--TADLAILGA--SASG--QFARVDATALAAHSGAPVLQIGSR ->tr|A0A1F8ID86|A0A1F8ID86_9PROT Uncharacterized protein OS=Caulobacterales bacterium GWE1_67_11 GN=A2093_02135 PE=3 SV=1 -MTLRSVMFHLDDGDAPLRFAPPFLQFARDYQVRDLVAAAPGRLPdpfvaaafplaqaqarereMYDLIESLQQALCEaaDGFALDFRSAGVLDVTAFLLDQAA--RCDLIVTRQHRALDT--DLGQADLSRLVLQAGRPVLAVPRS ->tr|A0A196NBP4|A0A196NBP4_9SPHN Uncharacterized protein OS=Sphingomonas sp. TDK1 GN=A7X12_17230 PE=3 SV=1 ---MRSILLPLCDPALDRHAISIGTDLADRLDAQVTALLPLTDFAslpvhghypytagwdefiegtqasAERREVEARQAFEAheresgVPT-RLSLRTVYGNEDAVVARAAL--THDLVLFARQSTDEDDPLPTSSLLKTTLETAGRPVLVVNGD ->tr|A0A1F2ZV60|A0A1F2ZV60_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_66_14 GN=A3D94_15195 PE=4 SV=1 --MIKSILAVSEGGPDAAMSFRLAARVAANFDGTVDALHLPVGPAggivgglamsgeampllididderLEARAKESERAYKEiva-PIKGATYTAAQTATLDTLVAMGR--CADILVLGRPGADPE--NVAPATVEAALYECARAVMIAPPT ->tr|A0A1I1GVB8|A0A1I1GVB8_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Devosia psychrophila GN=SAMN04488059_102315 PE=3 SV=1 -EQNARLLFLLPVATYpdptTKLGLGSALAMASRFGAGVTAVVQEVDITpihsavgeavlgvsrlageaearSRDRVREIREWMQDradrlaVPIELQTIRSRPEGFADDLFPAAR--CHDLTISILDTSD----PQRLAETEALIFETGGAVMVIPAT ->tr|A0A1V2ADK1|A0A1V2ADK1_RHIRD Uncharacterized protein OS=Rhizobium radiobacter GN=BV900_26935 PE=4 SV=1 -MSFATLLQITTGE--pASPESNMDFNLADAMESHLSVLLIGIASPppvgahmesvsaawlderQADQDRLARQVFALenylkgkisSFDIEEAYTE-IFNLDNVVGYRAQ--FADAVAIGPDILND--PGVRDAILDGALFHAGVPILVDPLR ->tr|A0A127VH80|A0A127VH80_9SPHI Uncharacterized protein OS=Pedobacter cryoconitis GN=AY601_3738 PE=3 SV=1 -KKLDKFVFATDMEDSDLNIIQALAEFAKPSHAEITLAHIQHPDTPEadtkklvtGFLEDVANKINYPKI--YYRAVEHTPVKAGLKWLAENVTCNVFVMVHRHKTFLEQLFNLSNTQKMAANTNLPLLIFPCA ->tr|H1YD67|H1YD67_9SPHI UspA domain-containing protein OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_2986 PE=3 SV=1 -INLKTIVFSVDLKKYYPKAVGFLIDIARIHQSQIITLHIGTNSDINpsQFVNMIQNVFEYTHV--ASKQIPGEDVGEKLEEFLLLAHPDLTVMVHHQRSIFGEFIPGSNSKKMLYRHKTPLLILRD- ->tr|A0A0P0NIL1|A0A0P0NIL1_9SPHI Uncharacterized protein OS=Pedobacter sp. PACM 27299 GN=AQ505_17045 PE=3 SV=1 -RDFGKIAFATNFEHpqQDVEDICNLISLASVFGSDILMTHVHIALTQSvdhqlianELLTGIIQKANYPNI--FYRSVENEDTRTGLDLFFDDEQIGLLVMVHRPHDFIDVILRGSRTQKMAARITIPLLVLPDG ->tr|A0A172TR59|A0A172TR59_9BACT Uncharacterized protein OS=Flavisolibacter sp. LCS9 GN=SY85_02680 PE=4 SV=1 -KGIEEIVFCFDASASSLFAIKEFTYLFPQFQsKKITVLEVRNDiLEEMGEDVAKTREWLEAHYQNVHFRFLEGDVKDELFTYFLLKKDTFIVMGSFGRNMISQLYKKSASETIIKTIDLPIFITHH- ->tr|A0A1F3TX13|A0A1F3TX13_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFCSPHIGHO2_01_FULL_40_29 GN=A2622_00285 PE=3 SV=1 ---PEKILIPCDLSERSHHAVHQVQPFLRAFKAKSELYHVVPQPLPILDFQSYVQFSEKikrseaqkrkafkKKHPQLKIVDSEGGVVEQIQKRLE--NFDLLAISPKTSLKAKP-FFGSVTSKLLRSGDKPILIAP-- ->tr|E7QZB8|E7QZB8_9EURY UspA domain protein OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_20627 PE=4 SV=1 ---MKRGVIAIDETEAHETLLREAGQWAAAADAKLVVLTFLDESEYEkgvetlesvgkvenvsydtgavteaaaDDAAAFAAGVLDGMGVEFTTVAAVvgdKERGSRVVEAGEKYDCDHAFVVGTGRSPTGKALFGDFAQQVILNFGGLVTIT--- ->tr|A0A1G7NCX7|A0A1G7NCX7_9EURY Uncharacterized protein OS=Halorubrum xinjiangense GN=SAMN04488067_107135 PE=4 SV=1 ---MTRGLVSLEATDAHRDLLAEAAASARGSDDDLVVLWHLDADKYDedvttleavgrienveydhssivdgatAKARSFVTDVLGDSDVDVQIAVSVgseDDRAERVLDAAAEHDCGHVFVLGDSRSPTGKAVFGDFAQQVVLNFEGYTTVR--- ->tr|A0A231MZ04|A0A231MZ04_9GAMM Universal stress global response regulator UspA OS=Zobellella denitrificans GN=CGX12_09040 PE=4 SV=1 -MPYRNILVALELNHREKPLLKRAVELAECHGAALHLVHVEPDVSGiyvgslnmdlrqlkvklrLESGHEIMKMLTDTQHHISSVSLPSGDVRQAVRLAVKEKNADLLICGHQLEHHFLGHLF-SHTVGFLDIDGCDLLVVK-- ->tr|A0A0X8X107|A0A0X8X107_9SPHI Universal stress protein family protein OS=Mucilaginibacter gotjawali GN=MgSA37_02006 PE=3 SV=1 -EELKKVVFATDFDESDMLAIHYLAKLSKLLNFELEIIHIIHPDKSgkekSQKEIELEEQVSRLKYPSVTYHDIKGnDVAENILRIYKESGAGLLAMIHHQHSFIMRMLHQSTTKKLLDNQEVPLMIFPS- ->tr|A0A1C2GR19|A0A1C2GR19_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PPCGB 2223 GN=BEL04_06450 PE=3 SV=1 -KPIWKIIFATALHDRDIAAASYLVNLARVLGAHLEIVHMLPLAGGeteEWQEARFMHLLENFKYPLITYHRMRAkSISAHLQHEGKEYGADTLALIHYHHGFLTGLFAHGTIRQLLAHHNLPVLVLPA- ->tr|A0A1Q3UIV8|A0A1Q3UIV8_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. 44-25 GN=BGO48_10230 PE=3 SV=1 -NALKKVTLAIPFELADINAINYLTGLGKQLNFHLEIVHVSLLEKSedTIKKNAIVSHINAIKQDNITYLEIRGkNVVKRLNRLCKDKNSDLLALVHYQQGFLSGPFDRSTTVAALDNQRIPLLVIPS- ->tr|A0A1J5DFN3|A0A1J5DFN3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_63_29 GN=AUK47_23075 PE=4 SV=1 -PPLRHLMATSDFSEDSERGVRWAYQLSRALECSLQLFHAADIPPAaivpgeppywipkiaieeleQRSLVRLKEFVEAEKFDSVSYRCQaSTVVAETIAEAAEAQNIDILVVPSHSRGVVEAFFVGSTTLRVLRLSRVPLLVLPRT ->tr|A0A1W9GKD2|A0A1W9GKD2_9BACT Universal stress protein UspA OS=Nitrospira sp. SG-bin2 GN=A4E20_00915 PE=4 SV=1 --MYKTIYIPVDNSDHSNTAVDIGVHMAKAFGSKIVGSHVYAAKMHDkrfkqmeaglpeeyhdekeldrqrqihdslitrglqiitdSYLDYVDKKCNEANL-PIERRSLEGRNWKVLAEDINTNGYELVIMGALGVGAVKDSVIGSNTERVVRRVRNSDMLIIKN ->tr|A0A1F3SLJ9|A0A1F3SLJ9_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA2_49_15 GN=A2X86_07670 PE=3 SV=1 -----SLLIGTDFRENSKNALRTGLIWAKQMILESHVTYVHSSPVSRKALKSAhiidqtsEEYLEAsliekiknqvsvldptgSKVQNIHYKILYGQPAIELARQATEMNPELLVLGTKERGPLGQIFLGSVTEKIIQTCTYPVLAVRD- ->tr|A0A1J1A9T6|A0A1J1A9T6_9EURY Universal stress protein UspA OS=Halodesulfurarchaeum formicicum GN=uspA2 PE=4 SV=1 -GSDGDVMVAVEDPAQVAQLVRTARDIAQGYGGTVRLVTVVVKPYESpfgmfsdetivqefaadsHELLDRAP--DPEGV-EVVRDLVVArSVEKGLVSAVKRTNPAALVIGWDSDPRRSDALLGTTVDHVLEHAPTDVYV---- ->tr|A0A1G3TJ38|A0A1G3TJ38_9HELI Uncharacterized protein OS=Sulfurimonas sp. RIFOXYB12_FULL_35_9 GN=A2345_07345 PE=4 SV=1 ----NTVMVCIDHHEESMDAVRYAKRLSDSLRAEFIALQITSEVH-gntrkSEQIRKHLKLAERLGAN--VISKISGDKTDAVIEAIEEYGVTELVMTRPKS-RFLGLLFPNLTKSVMDRKPqCTIDIVPFE ->tr|A0A0P7Z5A9|A0A0P7Z5A9_9CYAN Universal stress protein family protein OS=Phormidium sp. OSCR GN=HLUCCO16_14120 PE=4 SV=1 ---LRYLLIAYDDSNTAKTLVKQISETARNrpenSLEQCLVAWAVESKSRreipqsqtiedaEEKLAAVKQELEQLNLT-VATEVRQEERLQAMMSLAMEYDISAIAVNSPSVPRLLEWSRPNFANLLLRRSWHPVLFFPDP ->tr|K9Z2I1|K9Z2I1_CYAAP UspA domain-containing protein OS=Cyanobacterium aponinum (strain PCC 10605) GN=Cyan10605_0444 PE=4 SV=1 ---NSFWLVPYNHAPHHRYILEKIRGYVEIdkgnTLKECLFLSVIDEVSRseiltenkvkeaENKLAEIQKSFVSSPIN-VQTLVKRGNILEETFKIAFAHDVSAIALADNLKEdsifnRLVQLAVGNNANYLLNCSWFPLIYFPMN ->tr|K1KUM2|K1KUM2_9BACT Uncharacterized protein OS=Cecembia lonarensis LW9 GN=B879_03538 PE=4 SV=1 --QLLKIYVMVDFSDYTESTLKMVKDWVAGKKAEIKVLHQLDFHLPTlanhdlrlkllydhkrELLNQWFRLREEIFGSsdAISFEILEEPILEYLKK---TDQDAMIFMGLKGGGILKQIFLGSMVSEVIERINYITVAVPST ->tr|A0A136MPN9|A0A136MPN9_9BACT Uncharacterized protein OS=Chlorobi bacterium OLB6 GN=UZ06_CHB003000288 PE=4 SV=1 --MKKRFIVLVDFSRFSAPLMRYVSSWSLEADAEVLLMHQPTPFYPIfitpetrrtitrhtkaEALKKMDLLATSSIDHrvTVKLLAPIKPLWYILNRTLKQPYDSIVVTGLEDAGFLRQLLDPKSPVQVIENTSNLVAAIPGG ->tr|S2E1W8|S2E1W8_9BACT Uncharacterized protein OS=Indibacter alkaliphilus LW1 GN=A33Q_1125 PE=4 SV=1 --MSLKLIVPIDFSKYSLQQLRLAAAWKEKYGIEIMILHKVDLVFPSlanadlrlkmeynlkrEAKNNINELL-eevGLDIN----NETqiiSGSLIEFFKNSPKVSKDDIIVLGIKGLDTFSRILIGSTATQLIDNLEHVIIGIPLD ->tr|S7WRC8|S7WRC8_9BACT Uncharacterized protein OS=Cyclobacterium qasimii M12-11B GN=ADICYQ_1779 PE=4 SV=1 ----------------------MACSWQEIFNLDLVFVHKMDGIAPTlpisnkkeideiiefnkk----ESKTKFLkylqegALSPDsnKTSFEAVSSQLAHFL--EGFLKPNDIVLLGLKGTRFLKKILIGSTASTLINQLNHIVIALPRT ->tr|A0A1M7P7A4|A0A1M7P7A4_9BACT Uncharacterized protein OS=Cyclobacterium lianum GN=SAMN04488057_10794 PE=4 SV=1 ---MKRLIALLDFSEYSVPLIQMAYQWKVHYGMKLVFVNRVPGMIPTvadkttrkqlisfeke----EAKKNFLdlldktNLNHSDDIFLAIDKPLVPFL--KTYLEPNDVLFLGLKGTGPLKKFLIGSTATNIINQLNHLFVGIPKT ->tr|A0A1M7ZXG7|A0A1M7ZXG7_9FLAO Uncharacterized protein OS=Flavobacterium cucumis GN=SAMN05443547_1910 PE=4 SV=1 --MRNRTITLFEFSEDNEKLINFSNNLATEINSNLLLVHQTDCLIPSftdsetkkkilevekkEAIAKINEIIDL---KthDIECEITEKNVVNYLESLHDSSVCDWVIVKQKEKEEFERFFTKSTILKIIEETNSLLIALPQD ->tr|A0A1M6ER69|A0A1M6ER69_9FLAO Uncharacterized protein OS=Aequorivita viscosa GN=SAMN04487908_106133 PE=4 SV=1 ------------MIGAKKPMQKFYCII-------------KHPFLPTfaeneardyiiqqendKARAKLKALAEELIPDfiEVSFYVSEIDFHQTLPQLLSEPFENLIFIGLQGTGVLKKLFLGSVALRIIGNTDNTVVAMPKG ->tr|A0A1M7XXG1|A0A1M7XXG1_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_00449 PE=4 SV=1 -QQKGNILFATDLSINMHKVFEQAALMAINFNTKVTILHVLVDNPEAKrhmmsifgddqyqnirrehqeraqkvltgkntearkiqqaltkvfFEQERKLNFTDTDTFIDKILIAEGpSIADEIYSTATDEGCRCIVMGCPSQGLLSGALGDKILKKVLKVSKIPVLVVP-- ->tr|N1MKL9|N1MKL9_9SPHN Putative universal stress protein OS=Sphingobium japonicum BiD32 GN=EBBID32_16180 PE=3 SV=1 -RRYRDIVIATDFTEASLQALQTVAAFF--PTSDLTLFHGYDIPYAGFIVDRdieselrsiekeittkfmADARITPNVKSRTAVMIEHGSPDALLGDFIDEHSSDLTVIGSHGRGAIFDALIGSNAKRLVERLEGDLLIIR-- ->tr|K8GGZ4|K8GGZ4_9CYAN Universal stress protein UspA-like protein OS=Oscillatoriales cyanobacterium JSC-12 GN=OsccyDRAFT_2720 PE=3 SV=1 --SLRHVLLVVDNSSATQQALAVIYQLVGAGIHQLTLLHVQPPLNVsylvspfvarsssrqlnqslqdaqreqgEAILQRALTAIVIPSL-EVQTRLRIGDPGPTICQVATDLDTNLIILGSDPArrsllsplqamrvphrprpesnniSILRNTRLSVTEDYVIHYAPCPVLLCRTN ->tr|I4Y9R3|I4Y9R3_WALMC Adenine nucleotide alpha hydrolases-like protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_69627 -NDpenhDRRVLIAYDESSESKGALQHYIDYIAQDNDHIFLVTVLRPLErhldysvycaeeeatdagrkidprigaFFRDRNDALKRLKEEREritpllaprnITLTLHVAHGDPRETIPRVSKWHSAQLIIVGKRTLGRWQKIFHPSVSLAVIEHTKTSVLVV--- ->tr|A0A1M5YCF2|A0A1M5YCF2_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfofustis glycolicus DSM 9705 GN=SAMN02745124_03851 PE=4 SV=1 ----TRILIALDSSPRAIHLAEHAAKMFDCRKLSITLFHAVRGISVSmqglesifpddyaknitqdaqakidPIFDRAKSVLIEAGVAadNIAIKTVNGVSSraTAIVEEAAKTGCGTIVCGRRGVTQVADFSMGRVANKLTQLVH--------- ->tr|A0A0R1ISH1|A0A0R1ISH1_9LACO Universal stress protein UspA family nucleotide-binding protein OS=Lactobacillus farciminis KCTC 3681 = DSM 20184 GN=FC68_GL000 --------MAIDGSQNSNRAFNQAVQLAQRCNANLYLTRVVedyylneddgilqmvnyeDDPEVVAARDDLNQKFMMTVYPITDTFLRIGDPKKIIADYlVRGLKIDLLVIGKFGKNNNRRTNLGKIARFLKNNVSCQVLIV--- ->tr|A0A1X4GL98|A0A1X4GL98_9EURY Universal stress protein UspA OS=Halorubrum ezzemoulense DSM 17463 GN=B9H04_10255 PE=4 SV=1 -GRFERVLVVATDDPAGRAAVSTAVDLAATHGAVVDALYVVDTAEAWdvvverrertgeELVEAAEDAGAAVGV-DVEKWFRYGTTHREAVDFAAAHDADLVVVGSARRTGLDRLLRPDpVPARVRRGADVPVMVVGPD ->tr|U4L883|U4L883_PYROM Similar to Universal stress protein A family protein C25B2.10 acc. no. O74782 OS=Pyronema omphalodes (strain CBS 100304) GN=PCO -RRSRTFLCGTDQNDYSEFALEWLIDELVDDGDEIVCLRVVDKDSkissdqamqeklyrqeATKLLDQIIEKNEDEKAVSIILEFAVGKVHETIQRMIHIYEPVILIVGTRGRslGGLQGLLPGSVSKYCLQHSPVPVIVVRPS ->tr|A0A160NTH1|A0A160NTH1_STRLU UspA domain containing protein OS=Streptomyces laurentii GN=SLA_0833 PE=3 SV=1 ---PSSVRRGRRGRQQGLPG-----GRRLRRGGGEPARGTTACPLGvvplllshdnvaqelsersRLLAESVAGCSERYPDVDIEQEVVRGHPVEELTRASR--ESLALVIGRRGHGG--------------------------- ->tr|U9SX93|U9SX93_RHIID Uncharacterized protein OS=Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) GN=GLOINDRAFT_284888 PE=4 SV --MGKKYLIPLDGSDHSKYSLLWAFENLINPNIDSVLLLSVGVLSAgtpceysavtrnilngdneidlerQKAEEKAKEIVNDGKLivknllktqeLPIECFVSsNSDPGRYIVNLSREQKIDVLVMGHRGTSSPDATNTGTVAQHCMHSAGCTVVITR-- ->tr|A0A167HII5|A0A167HII5_9FLAO Uncharacterized protein OS=Ulvibacter sp. LPB0005 GN=ULVI_08680 PE=4 SV=1 ---MKKILIPIDFTFKSYDAIDYAVSFFKREKCHFYFLNTYSYDieglnavnllqagddffekPKRESEMSLGRVIQKITSKcenkrhQFNAISEYANLIEGVRKAIKELDIDLVVIAGKVQTKRATDTYSKNTKRILDNIReCPVMIIPAS ->tr|A0A1X7L5D7|A0A1X7L5D7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Dethiosulfovibrio salsuginis GN=SAMN06275492_1478 PE=4 SV=1 --MFKRVLIAIDLKQNPDDLISCISNLKLKSIEKVLLLNVIDDRINpsfdkdviAAKLEEYGLKLGLPGD-KIETQISTGLPFDEIICQANRWEASVIAIGPGHGPTWASSWIGSTALRILEYSPIPIMTCNSG ->tr|C6L1E5|C6L1E5_9BACT Universal stress protein family domain protein UspA OS=uncultured bacterium PE=3 SV=1 -MSIRNILLAHSGTSGFPSSLGHAIRVAKKHNAWLTCIYSGSTSFFDqvlvlsdelreklgavrtAKIDDLRQQFDQEAAAagigeKAQFLLPATVGKLTISDVAR--NFDFVVTGYHA-KLPNDEYRAASPDLIALQSGRPVLVVPDG ->tr|A0A154KWK1|A0A154KWK1_9PROT Uncharacterized protein OS=Thalassospira xiamenensis GN=AUP41_16485 PE=4 SV=1 -MALKDILVPYNGQNTANCALKQAILLAEKHAAHVTACFPYDPPAVVstarqlmskrleeqfhqivdrmevEARSAIRQAFDEQVAGvsvpeRVHSLEIIGNSDIAVTKAAR--HFDVTFIGQNL-SGYSDGSNMIHPDVIALRSGKPVLVVPHR ->tr|A0A1B0ZMG7|A0A1B0ZMG7_9RHOB Uncharacterized protein OS=Phaeobacter gallaeciensis GN=JL2886_00442 PE=4 SV=1 -MAMRNIVMPIAPGRYDPSSLRRAITLAKRLPCHLDVVFLLPDPKETfiytgiepteqdgplsdirdrmedhgrSAAEASRRLFAKLRKEaglelrqkpslastaSGAWHRIKGEPQEMITPLAR--RADATIFTPETARY--TLMADNVLEAALLRSGRPVLYLPGE ->tr|B0BZR2|B0BZR2_ACAM1 Cl-channel, voltage gated, putative OS=Acaryochloris marina (strain MBIC 11017) GN=AM1_0946 PE=4 SV=1 ----GRILLPLANPDTAEPLLKVAVAMAQALNYELECLHIIRLPRNrlpaetpvqtvkgRRLLQKAIRYGQRHQV-SVHTQIIaAQDVAQAILEVEQTEHINLLLMGWQGQFFSGGQIGNPTVRTILQQAKSQVLVIR-- ->tr|A0A075FHV8|A0A075FHV8_9ARCH Cl-channel voltage-gated family protein (TC.CIC) OS=uncultured marine thaumarchaeote AD1000_100_C06 GN=TC.CIC PE=4 SV=1 ----SRVLVILQEDSEinRRSLVSLAAIIAKKKAFDLECLHVQANTKSdndhRLLVQQAEAVARELVV-TVHTSVRlAKHQATAVGEIIDRRPIEMVVLALNSATDL------IELELIVEQTTCPILASS-- ->tr|J6J0I3|J6J0I3_9RHOB Putative stress protein UspA OS=Rhodovulum sp. PH10 GN=A33M_4302 PE=4 SV=1 ---GRRPIFAWGETAGAARALTDALPLLSpDADALVLYAYERDQ--RNDFAERVIPHLERHGVKarFEPFVLEEETVMDVLLNFASDHGADLMTLGIAGRAGAGRFERGRGGMPTLRQLTVPVLC---- ->tr|A0A0D1ZCM9|A0A0D1ZCM9_9EURO Uncharacterized protein OS=Exophiala mesophila GN=PV10_03736 PE=4 SV=1 -RAGRLYLVCSDLSTEASYAMEWVVGTMLRDGDTLLAVYAIEDENAGktteadreilqaegtqagkdatdvmatltrqttqgggtsvgldlrnkyipatEaqsltgsvdarktskkqmerlraveeITGNFIKLVRKTTLQ-VRCMVEvihCKSPKHLILGAIDTLDPTLCVVGTRGRSSLKGVLLGSFSNYLVTKSSVPVMVAR-- ->tr|Q0CYD5|Q0CYD5_ASPTN Uncharacterized protein OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) GN=ATEG_01299 PE=4 SV=1 -RRRRKYMVATDLSEESVYALEWTIGTILRDGDTMFAVCAIYDESASsatqngdgakamqdvaavvgsqteettlkpnndsgtnlprailgrlgtGtdskpgsvdsrgmskteservravesISQTCVRLLRKTLLQ-VRVAVEvihCKSPKHMITEAIDGLDPTLVIVVCSWVRSQTT--------W--------------- ->tr|A0A1V6I5F1|A0A1V6I5F1_9BACT Universal stress protein UspE OS=Bacteroidetes bacterium ADurb.Bin035 GN=BWX61_00762 PE=3 SV=1 -DRIKSILLPIDSTAETTNKLPWAIEIAKYSNAEIHIFGAYITDlstmknKVDKNIVMIENELEKENIKFKSFKKSITNYTSDLISYIEDNNIDLAIIMTEQENRNTNVLLGQYAMQMINHCPVPVLSVHQD ->tr|A0A1E3WB02|A0A1E3WB02_9RHIZ Uncharacterized protein OS=Methyloceanibacter marginalis GN=AUC71_12265 PE=4 SV=1 ----ETVVIAWKDAPEAVRAIAAAAPFLEAAK-RVRLISIAEDGeEEEdDTASAMTGYLAMAGLPVEMETVPLgGrEVGDACSRPPA---------AAFSSSWAGMGTGGGANGSSAARrsmscatRTSPC------ ->tr|A0A1J5BRL5|A0A1J5BRL5_9BACT Uncharacterized protein OS=Caldisericum sp. CG2_30_36_11 GN=AUJ99_00915 PE=4 SV=1 --MFKKIMIMVDNSSIMEDVVQYVTNLF--PDAFYYLYGVINLGAFsgyysrivsqqmreisSETLKTLSLLLESKGIK-FNLFLDEGDPVSTSLAFARKNEVDLFVLETHAGLSVNKIKLGKTTLSVIQHSHIPLFLVGED ->tr|J3N5A3|J3N5A3_ORYBR Uncharacterized protein OS=Oryza brachyantha GN=102703338 PE=3 SV=1 -RYRQLHETEMHPAGTHPANdDDHHDL------------------------------------pn---------------------------------------------------------------- ->tr|A0A1M3DT88|A0A1M3DT88_9FLAO Uncharacterized protein OS=Chryseobacterium sp. 39-10 GN=BGO40_07230 PE=4 SV=1 -NAIKNILIPLDFTRRNEKFLNIAAAVANRHGAKVHVLNVIPFSllgtgsvssgkfffhenamieSAEKQLATYRMVMRKITNEDVIAQHAIGAVATEVLKYSKQKNIDLILMPVQYPKRRPG-FISSNTYEIISNSAVPVMTIPEN ->tr|A0A0Q5ZDC9|A0A0Q5ZDC9_9BURK Uncharacterized protein OS=Ramlibacter sp. Leaf400 GN=ASG30_08695 PE=3 SV=1 -TEIRQLLVHLDAGRRIRETVSCARRLAADHGACIAAVHAPVPAMAElpivpglgpaaqsflefqkerrRAVHASFERAMRdpGPAVEATWGEVNEFPLaGTFAEAAF--SADLLVLTQPDPQHRAEDVPHDFNEAVVAASGKPSLILPPS ->tr|A0A246Q1Q0|A0A246Q1Q0_9BURK Universal stress protein OS=Achromobacter sp. HZ28 GN=CEY04_28060 PE=4 SV=1 --MYKRIAVHVDRDGAFERRIAAAVGLAQAHNGEVVGVYVQDPPYVYgynesltptavlevqrrlinderQQVQRTFEHLTASAGVPNSWSSVEGLRDVELAVQAR--SSDILILSQPDADFSrRSSIEPYQLETVIMTAGRPVIVVPYD ->tr|A0A0N0TBD5|A0A0N0TBD5_9NOCA Universal stress protein UspA OS=Nocardia sp. NRRL S-836 GN=ADL03_01870 PE=3 SV=1 -MSSRPIVVGVDGTPASDQALEWALDEAAVRGCPVHVVHAWTFEALtdwtetTEQRTRAESEAlidkavqaaaeKRQEMPEIVRQSLRGEAAETLERALE--GAAMVVVASHTGHRLRQIVLGSTSMHVVRHAHAPIVVIPVD ->tr|B6EGV0|B6EGV0_ALISL Universal stress protein OS=Aliivibrio salmonicida (strain LFI1238) GN=VSAL_I2982 PE=3 SV=1 -KLYQTILLALNPDDSkAHKLMVKAGVLAKQNDAELHVIFVEVGIGDvnymdvelelesshnaleFKRIEQLSILSKESPYPVRAVHIADGNIVKHISEIGDKINTDLVIIGYHKSKIH---WGRTLGDEVSDKLKCDVMIAQ-- ->tr|A0A132N7F7|A0A132N7F7_HYDSH Histidine kinase OS=Hydrogenibacillus schlegelii GN=TR75_07135 PE=4 SV=1 ----PKILVLVSDGGNAERLIRRGWRIAQRMKAELFILHVPTKPadRLseaeRKKLREIEALAKILGGKFFIRAAGGRPVIDVIVEFIKENAITQVVLGQTGMSRWQEILRGSLANRIMERTRfVDVLIVGNG ->tr|A0A1R1R2C7|A0A1R1R2C7_9BACI Histidine kinase OS=Bacillus paralicheniformis GN=BVL54_12525 PE=4 SV=1 ----EKILVCVQHGKNAEKLIRRGWRIASRLKADLLVLNVSRTSkeQLapteRDKIGQWETLCAQFGAEFIFKHSNKRRISETITDTAKQHGITQIVLGQSARSRWEEIRKGSIVNSIMRHTDgIDLHIVSDE ->tr|A0A1S1FST7|A0A1S1FST7_9BACI Histidine kinase OS=Bacillus sp. HMSC76G11 GN=HMPREF3291_02140 PE=4 SV=1 ----EKILVCVGYGPTAEKLIRRGWRMANRLKAQLFILNVTKNSpeAFtqeiRERTEQWKILASQFNAVFLLEQEASRKPAQVIIDIAKQHHITQILLGQSARTRWEEIRKGSIVNTIMRKTEnIDIHIVSDG ->tr|D2S2I9|D2S2I9_HALTV Uncharacterized protein OS=Haloterrigena turkmenica (strain ATCC 51198 / DSM 5511 / NCIMB 13204 / VKM B-1734) GN=Htur_4822 PE=4 --MGGHVLVVISRTAPSTDILEYAFQKY--PNAKITVIHVTTARSPFdpfrnrdpceyvipelgseqseellpapdlftraqqkraeNVFSRAYELSERYDK-AIESVVRSGDETEEVVTYAENHAVDQIIIAENSLIEL-PLFHQNVSESVAHTTSIPV------ ->tr|Q9HIM9|Q9HIM9_THEAC Uncharacterized protein OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) GN=Ta130 --KFDRIAVPMAEGRSSRRVLHIAFAFASAMGSEITAITVRDQAKDITWTNkitvvtNAYKEGLSQNIKVVPKILTSSDVKSALVEELNRHSYDIVIIASEKRSIITRITSGPVSNYVIKKSNIPTALV--- ->tr|A0A0D2GK78|A0A0D2GK78_9DELT Universal stress protein OS=Dethiosulfatarculus sandiegensis GN=X474_05390 PE=3 SV=1 -KRFRTILFCADEVEKPGSVYALLEDLGEVKGIRLHVLHVLPSLHRYmptetildqssgqvtqassEFMEKTLSKLRrcyphpEGQPGKYRYKVCVGTAYVEILRYIRENPVDLIVLGAMGPSKYGRTHYGSTVEKVCAKARCPVVIV--- ->tr|M0M3F7|M0M3F7_9EURY Amino acid permease-associated protein OS=Halobiforma nitratireducens JCM 10879 GN=C446_07397 PE=4 SV=1 -----NLLVAITEATperARRDMLRVALDLGRLRSTAVSVVEFSDEPehilpsrhsrvrstaLPAWFPDdpedapdwfpsealegdlrtsggepvaATLEDPDGHDTQVDYRRIVSEDHKEAIVDFATFEGIDLILTQRHASNGi-PGFLGTDETAWLRQNAPCDVALVED- ->tr|A0A102CZ79|A0A102CZ79_9BACT Universal stress protein OS=Rhodothermaceae bacterium RA GN=AWN76_01955 PE=4 SV=1 -----RLMVALANPHHEADLLRLARFVatGRTAGGDVVGIHLHRVPlqtpldvarerldervsVERTIARllqqetlPAADGLPLARTRITTVTDVAHDVFGSLISETQRREADLLLMGWQGGFT-VGRIYNSPVQRILAEVRADVAVLKN- ->tr|X1A1K0|X1A1K0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=S01H4_00620 PE=4 SV=1 -----KILVPVKNPKTAKSLISLAGFIarGNEKL-TVTALKIVKVSqnisisaaqkyilkkpnYRKIL-Hmvenfa------KKKDISIHTILQAAYGITSGILSMVREINPRIIILGWRGPIT-FHRIYENPTKDIIEKSNCDVAVLMD- ->tr|U1PGC3|U1PGC3_9EURY Amino acid transporter OS=halophilic archaeon J07HX64 GN=J07HX64_01185 PE=4 SV=1 -----RVLVALWDSGetdHRSsnreDLLDMIsVLESHSLDVDVQVVEFEQARketfskqhtE-----Iaadtpaw-----IQ-AYDDVSYRRVTARDVRQSIVEYASYNDIDIVAHGFVPDAG-PVGIVADDLEWAIKNTPCNSVVLAG- ->tr|A0A1I0JP09|A0A1I0JP09_9EURY Amino acid transporter OS=Haloterrigena hispanica GN=SAMN04488694_15310 PE=4 SV=1 -----HVLVETFEGEtn--PLLCTLMNAFAEEFDADLEVLAISKIPpqtpivepvshaDADWKEPiesaht-----LDRDEHTVSFEQIRTHDRGAALIDAIR-EKTELVLIDWHDPIR-KYHFRESHVDEILRSpLPVRLAVLKY- ->tr|A0A238VWT7|A0A238VWT7_HALVU Amino acid transporter OS=Halorubrum vacuolatum GN=SAMN06264855_104170 PE=4 SV=1 -----DVLVALTESTtpeAARDMTRIGLDISRLRGGLIDVVRFDSHPhrvftahtdrleeptgtLGDWLGFgeeppswfpmesaeesagsradgsgsrdtdsttsrgdggtealahppeEPLRVEEPERGRLQRHVVSTENVVDSVAAYAAHEGIDLVLAERQTADL-HRALFGGETAELLREVPCGIALVED- ->tr|Q6FCQ8|Q6FCQ8_ACIAD Uncharacterized protein OS=Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) GN=ACIAD1277 PE=4 SV=1 ----MKFLVGYSNDSSGKDALKLGVALAEMTQGKLIVCHIVAKTWHNialakfdedydqflcdeaqKALDDAKLAV-PSHIEARYIARTALSISEGLKQTAKELSVDCMVISGARIAIKGQFFSGTVADELLNQLSLPVALAPKG ->tr|A0A0H4W541|A0A0H4W541_9BACT Universal stress protein UspA OS=Rufibacter sp. DG31D GN=TH63_07600 PE=3 SV=1 --PIHNILWVADFAYEKQPqrSISLIKVLQRIFGAKIHLLQILQKEDAHqelALRENMMRFANNLQLENYELHFHRDfKVPTGVRNFNQESEKNLVVIGTHARKGVNHLFYGSIAETLVNHCIRPLLTYH-- ->tr|A0A1J4LQE8|A0A1J4LQE8_9EURY Universal stress protein UspA OS=Natrialba sp. SSL1 GN=BBD46_19905 PE=4 SV=1 --DIDSILVPIAGGPHEGLALETASALATQHDAVVHLLHVRSETDPAQREGEANALLLNAsdefdSETEIRREVAvDDHVAGAITDRTT--AHDVTILGVSRGGFVRRTLLGTISEAVGRNASGTVFLAKRY ->tr|A0A226WLU6|A0A226WLU6_9BURK Universal stress protein UspA OS=Caballeronia sordidicola GN=BSU04_43250 PE=4 SV=1 --GFKRILLCVDPTAASARAAAFVPHLANK-ETRVRIVGVVENAHAviplgplaafhlsaanalllqdvENACAASQELFASSGAKleirIIDLITHGGGVVHALAKAAQDWRADLLVMGSRQHQGLLHWVEGAVSEPLMKFAACAILVLPE- ->tr|A0A150IFA8|A0A150IFA8_9RHOO Uncharacterized protein OS=Sterolibacterium denitrificans GN=ACY05_00260 PE=4 SV=1 --MLQKLLIPVKNGEDARQAVAYAIRRRAEGvQVAVCLLHVEESGPGGDpgvvwhellektrhsrprPFDIALRLLFGLDI-DVAAYVRKGAVAFTILDAAEELDCQEIVMPAPHSGLlpFRWLSRNVVDTLLARQRSVRVVAVNRD ->tr|W0SIV1|W0SIV1_9PROT Uncharacterized protein OS=Sulfuritalea hydrogenivorans sk43H GN=SUTH_02057 PE=4 SV=1 --KVRRLLIPVKSAKDAGHAVAYAIRRRAEGlGMAVCLLHVEESPTQWQalsanaearavkrrradhIFAPAMRMLEGLDI-EFAAYVRSGPIVFTILDAAEELACDEIVVPEPGRGVFSLLSRRVVPVLMARQRSARLVAVTNA ->tr|M5WBX5|M5WBX5_PRUPE Uncharacterized protein OS=Prunus persica GN=PRUPE_ppa011515mg PE=4 SV=1 -MDVRRIVVVVEDVEAARTALKWALDNLVRYGDLITLLHVFSTSrsRNknktrllrlkgFQLALSFKDICNTFPNTKVEMIVTEGDQdGKKIAAVVTEIGASTLVLGLHDHSFLYRLAMAHGSSSIANKLNCRILGIKQP ->tr|A0A1K1QRL1|A0A1K1QRL1_DESDE Uncharacterized protein OS=Desulfovibrio desulfuricans GN=SAMN02910291_02149 PE=4 SV=1 -SAPKNILLLLDEES---PAAAEAVRIARESGAALTALFVLDSTWNdyvghdwlsgsgsradfidymqqeeeKSAARAFTRLREFAGDQmEIHCLTTSGNVIDHARQEMVR-GYDLFVAANPLRRGLER--IRGNVGALCENAPCRILLVPAA ->tr|A0A098LK72|A0A098LK72_9BACT UspA domain-containing protein OS=Sporocytophaga myxococcoides GN=MYP_3823 PE=3 SV=1 ---MEKLLLASDFSDSSNNALDFAKGIAAKAVSEVLIFNSAPLPVLEptiptfmmeeiledqeysakEKLRESCDLVSSERYfdgsrVSCGYKFSSGVAVNEIAEVAQKENVELVVMGAYD-NSITSKWIGSTTISTLDHVACPVLAVPTD ->tr|A0A1R4JYV8|A0A1R4JYV8_9MICC UspA OS=Micrococcus lylae GN=FM125_11410 PE=3 SV=1 ----MTILVGYAPRAESRAALNKAIDIARTTGERIVVVNAGPGGEHrssnllnEAQQRDLQQVLDGCGVDaEFRQYARGRSTAAEMKEVAAELEPSIVVIGLRRRGAVGRFMMGSVSDELLRELDQPVLCVK-- ->tr|A0A158RF96|A0A158RF96_HYDTA Uncharacterized protein OS=Hydatigena taeniaeformis PE=4 SV=1 -RRVRKILFPIDDSENCSIAFKWYLNYVRLPGDFITFVHVVEPLYTSGEMRidmenpevrfedvpktvesvmnrskalglNYMSLAKEAGLESRAFLHVDTQPGRAILTSAKNHNVDMIVMESKGQGILSGASLSRVSDYVVHNLTVPVVIVHAE ->tr|A0A1G2PXS6|A0A1G2PXS6_9BACT Uncharacterized protein OS=Candidatus Terrybacteria bacterium RIFCSPLOWO2_01_FULL_58_14 GN=A2991_03220 PE=4 SV=1 -----RVFVPVARDEDMRGMLEIGIALAKGREAaDISLVHIDETPGDhragreaehiate-PLLVRLVDRGREEGVGVEGSIIESDDPTRTALGIIAIHRMNLLVAGWDGHA-RQGRIFSSKVDAMLREARCDTIVVK-- ->tr|A0A1G1ZRY8|A0A1G1ZRY8_9BACT Uncharacterized protein (Fragment) OS=Candidatus Harrisonbacteria bacterium RIFCSPLOWO2_02_FULL_41_13b GN=A3I24_02355 PE=4 SV=1 -----RILMPIAPHLSldeIKNLAEIAFVLTSKYDGELVIVTVHEIHHAlpldqsmihpdliakeKEIFNQLqqwvakynqKTGPEVKDINFHSLILIGRDVVDVILEVIKMEDCDLLMLNWSGYRDGLNVILSRKIDRILRESKCDLLVVK-- ->tr|Q1NSH8|Q1NSH8_9DELT UspA OS=delta proteobacterium MLMS-1 GN=MldDRAFT_5054 PE=4 SV=1 -----NVMYATSFRQAHGVCVNFIKHPAFQAK-RLILLHVGRRAPDPEAEGKRLEQIKInleqlardcqDGFATIEKKEVVGLgVARKILRQARTSNIDLLIIGKVDTGGLLSSFTGSTAEAIYNSAPCSVLVIPG- ->tr|A0A1N6WCH0|A0A1N6WCH0_9SPIO Nucleotide-binding universal stress protein, UspA family OS=Alkalispirochaeta americana GN=SAMN05920897_11718 PE=4 SV=1 -----VVLYATALQRQDEYVLPLLSWPRLKVD-RLVLVHAGPRAPDPVAEHHRDQDVSRrlgalarscdIPGCLVDTRSVTGNARREILRIARHEGARLLVVGKSEKQGSLAEMVGSVAEAVAYNAGQSVLIAGQ- ->tr|A0A0H3K5J5|A0A0H3K5J5_SYNP6 Potassium-transporting ATPase D chain OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=kdpD PE=4 SV=1 ----ERVLVCLSTHPQSIRLLRRAARLSGAMDARLYVLFVADPqrfltKAEVLQLETCDRLCGMFE---GAFLRVE-stDVVGAIVKVATEQRVTQVVIGESPTSRRLWWWQRPLTDRLLQRLRgqgIDLHIISFP ->tr|E8V6Y1|E8V6Y1_TERSS Osmosensitive K channel signal transduction histidine kinase, sensor subunit KdpD OS=Terriglobus saanensis (strain ATCC BAA-185 ----ERVAVCISANPEARDLIARGARLAEGLNGELYVLHLTNErdnePERRKTLDAHLQFAMNLG---ANIVHLT-gkSVASATAAYVTEHRITQAIFGRSALHGLKKYLYYLAIQKFMSEAPhVDLHIITQD ->tr|Q7X1J7|Q7X1J7_9BACT Lfe123p5 (Fragment) OS=Leptospirillum ferrooxidans PE=4 SV=1 ----GCVLVGVSDRPEDAALVRRGAVLSDRLNLELKILYVRKEade---GLHSQVLVDLTRSFG---GVFLSEV-spqKWESHFIRRCQEIGPSLVLLGQSAWRPGFE----STAEMIARNLNqFPLLIIPLD ->tr|G4HHP8|G4HHP8_9BACL Osmosensitive K channel signal transduction histidine kinase, sensor subunit KdpD OS=Paenibacillus lactis 154 GN=PaelaDRAFT_350 ----EVIYVLVGSGPESERIIRRGFRIAYRLKAAWYVTPLPDRsedgkLSMPARRDPFQAMTERLG---GIFRPLELqgkqayDLPALLIAAADEVKATQLIIAQPPG-nGFPGSSQMRFAKQLLRRARhMDVLVISDG ->tr|A0A0S8B8W9|A0A0S8B8W9_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12300 PE=3 SV=1 ---FADILVLLEGIEDDWKVLDTVIKMASWDKDRIFGLHVVKdrsqvnSPAVQYICTEFERRCQAAGL-VGEFAVEVGILFERIVERAA--WADLVVINLTHPPQSQPLaRLRPGWNQLIQRCPRPILTLPN- ->tr|A0A098LFC6|A0A098LFC6_9BACT Uncharacterized protein OS=Sporocytophaga myxococcoides GN=MYP_2421 PE=3 SV=1 --MISKIVCPTDYSDNSFNAIKYLKDLAALSNANIELVHVETPIPH-SLSSEMEELLQDIK---HEKLVLWGNVTDEIVNEITKTHADIVGISSLGKNKEENFFISKVTLSIVNQSSFPILIIPPD ->tr|X8J719|X8J719_9FIRM Universal stress family protein OS=Mogibacterium timidum ATCC 33093 GN=HMPREF0581_1288 PE=3 SV=1 ---MKRILVPVDGSPRSLIALEQLKNTFSPKAFEVVLVMVRENTGYaltmaeeaeirEELDKRLTSIAKTIDNYKVITRSAIGRAGARVIEAAKECGVEMIVMTKSTKPGSGSS-IGLTASYIIRHAQCDVMIVKET ->tr|A0A126YU99|A0A126YU99_9BURK Uncharacterized protein OS=Burkholderia sp. PAMC 28687 GN=AX768_29730 PE=4 SV=1 -----RLLIPIINACVVTEAVRHATVLSKnTRDVTVELLEILPPPDqgrvvafhsisdqradelraGEAAVLASRAMLSQANI-LFTLTRVFGIPEQIIAAFVREHECNAVLIDTSSPNAFRTL---SLVTRIWRLTTIPITLLH-- ->tr|A0A1G1ZIB1|A0A1G1ZIB1_9BACT Uncharacterized protein OS=Candidatus Harrisonbacteria bacterium RIFCSPHIGHO2_02_FULL_42_16 GN=A3B92_01290 PE=4 SV=1 -SL-LLAAHPSGNSPYLKLMGEIFSSLKNYYKAKTELTSILAADTPFYLKPDPQILLKPLGLKRKDfeeiEFFKAKSVITAIIDEAKIKEISLVIIGATRPKFLGEIRFGNIPELLSKHLNTSLMIVRG- ->tr|A0A1G2DCL3|A0A1G2DCL3_9BACT Uncharacterized protein OS=Candidatus Lloydbacteria bacterium RIFCSPHIGHO2_02_FULL_54_17 GN=A3C93_05460 PE=4 SV=1 -MDRVFIPVAVDANPNLRFTGKVATALYRTFGAKVTVAMVVPEDVRgkgdEYYRSILEERVVELKMKIPGgvesKVIFSDYVASGIL-KSTEGAYDVVLLPAARGGITKVIGVGSIPEQVAKQCRrKTVLIAKG- ->tr|A0A1S8VRW8|A0A1S8VRW8_9FUNG Uncharacterized protein OS=Batrachochytrium salamandrivorans GN=BSLG_05077 PE=4 SV=1 ------SIVCIDRFPDSETTFDWACHNLvspppveHmsdsPPSEGLVLLHVVSPKELAlfwkstspvwtsmgksdahspiarhiddsirseytgkheptatdlkialdqiaskllsYYTARVIATQQSLNFPLRAVAILSNSPKDAICSTSSTAHPKCMVVGRKRAISFKSLTLGSTALHCLRHCKCTVVVVS-- ->tr|H0F862|H0F862_9BURK Uncharacterized protein OS=Achromobacter arsenitoxydans SY8 GN=KYC_14802 PE=4 SV=1 --MFTRILVDFDPEHLSHSSLLGLLDLAAANHSALTFLALRPKLDELlcasedefvedvrrqiaDEWGVIMSLARQRGL-DPRLEVLAGDPIEALLGYGREIDADLIVAGKSHSGGIRNAVLGLPWKDFLTRADVAVLILP-- ->tr|A0A084IKH2|A0A084IKH2_9GAMM Universal stress protein UspA OS=Salinisphaera hydrothermalis C41B8 GN=C41B8_10815 PE=4 SV=1 --GYETVLLDASSVQHRETIWDYTLRLAVQHGAYVTAIHQGA--peighsgdpgqldvyserretelvhKFE----ALARRY--AGVQ-YEWRS--deGDRVERVARHGL--YADLIVMGQFDPSDR-GGlGTYEDPVEIALMSGRPVLVLPRS ->tr|A0A1E3VTM3|A0A1E3VTM3_9RHIZ Uncharacterized protein OS=Methyloceanibacter stevinii GN=AUC70_13995 PE=3 SV=1 --AIKDLIISFDSLTAPDAQLPYAVEATEALGAHAIGVAHVPAGetaprae-AQRAMDRFASAGDQRGIS-WETRLATcatGKFAEQLSVQAR--HADLTIIGQPSSEGANGKHQTALYEELLFHSGRPVLVVPWA ->tr|A0A1F2YR00|A0A1F2YR00_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium GWF2_58_20 GN=A2018_04675 PE=4 SV=1 --AIRTILMHLTAEASAKARLEVGIALAHRFSAHLDIVFNVRPAhipaasagrgayvhymteainnahqMAGEIAHGIDTCCKG--LS-WSWGVVNeehSI---PLKARAN--TSDLLILPSAPMTYF-EDhFRWHLADCMAVDSACPTLVLPEG ->tr|A0A1P8S6Y8|A0A1P8S6Y8_9RHIZ Universal stress protein OS=Brucella sp. 09RB8910 GN=BKD02_11640 PE=4 SV=1 --SYKTVVAYSRSEAELKRVLSAiGLLRQKVPDIHVIGLYAIPSPivyadpngfidpgmfelhdkqhkeLSERLKHVFEEEMRRQGIN-YEFRVTRsdtGTAADGVLASCL--GAELLIAGQPDPND--PATNDETADTIVFNASCPVLLVPYA ->tr|A0A231UUB6|A0A231UUB6_9RHIZ Uncharacterized protein OS=Notoacmeibacter marinus GN=B7H23_14785 PE=4 SV=1 ---MTTMMLDLTCPEALDPLMKVAAPLAKRLPGRIVGAHISPAFegvapiepfalsdayydevrsryerdigkRAKEVDQALTKALSAEDLQ-G--nlTHATagpNGIGAKLARLSR--NYDFVLALQKGKVN-----VAIPPEVLALDSGRPVLVVPEA ->tr|A0A0N9Z679|A0A0N9Z679_9ARCH Universal stress protein family protein OS=Thaumarchaeota archaeon MY3 GN=NMY3_03478 PE=4 SV=1 -PSFRKILVTHDGKDKSNKAINYAIYLSKLSGAEITILQIINdvkkqdnvnniEGDLIDSMEEKIKKIKHAGCEKVSYKFKTGNTIDEIVDEINEMNYDLVVLTSSHLSSWMESLF-SNTRKIISNIHTSVLI---- ->tr|A0A1M6CVU9|A0A1M6CVU9_9BACT Nucleotide-binding universal stress protein, UspA family OS=Tangfeifania diversioriginum GN=SAMN05444280_104106 PE=4 SV=1 -GEIKKIVIPVDISQSTKKKLLWATYFAKKYGATIKIVSSLSlnisakKSLAWKNAEKLKQILLERNIK-CDVDILkakGKEKHEVILDYIKKENPGLIILRTHQESNMAGTQIGKFVSEIVHGSQIPVFTVNR- ->tr|A0A0F4FN82|A0A0F4FN82_RHIRD Sensor histidine kinase KdpD OS=Rhizobium radiobacter GN=SY94_3784 PE=4 SV=1 ----DRVLVCLDHGRNGPGLVRYARRQADRLRAPWTALHLDTPRSQqlseaeKDRLAGTMRLAQQLGGE--TVTLPALDLTREIIAYANANNFTHIIIGRPRKSWWQRIFQRSLTHDLIDHAGdISVHVISGD ->tr|M3EWT7|M3EWT7_LEPIR Osmosensitive K+ channel His kinase sensor domain protein OS=Leptospira interrogans serovar Lora str. TE 1992 GN=LEP1GSC067_471 ----EKILVSIGSSPNSYSLLRYAKRLAYERNGELFAIYNQTRENLtkenLSQLEKNLSFARELGCE--ILYAADEDTAEAILRISGQKSITRVVIEKSDTNWWWRWnSTASK---LARIPSnFELCLVPYS ->tr|A0A0S8FUG6|A0A0S8FUG6_9BACT Uncharacterized protein OS=candidate division WOR_3 bacterium SM23_42 GN=AMJ83_02680 PE=4 SV=1 --NFTRSLlVLTEDADQS--ILSVAVQFCKNSGSRLFVLFVIEPDRIsrlaslthqkvkvlhkkteedgWKLLYLIEDEAVENGV-WTSLHLEQGNLLQMTKHYVDAYEIDVLLIKKKEGSKR---IFVSCSVPVIGL----------- ->tr|A0A0S8JVW0|A0A0S8JVW0_9BACT Uncharacterized protein OS=candidate division WOR_3 bacterium SM1_77 GN=AMJ74_04610 PE=4 SV=1 --KFDKVLlVLTDDADQS--IMPDAVQFCKNAGSRLFVLFVIEHNRIarlasltqqkvkvvlnkteeegWKLLYLVEDDAVENGV-WTSLHLEEGHLPQVANHYIESYGIDAMLVKRKDEFRR---IFSTCPVPIVGL----------- ->tr|A0A235BX87|A0A235BX87_9BACT Uncharacterized protein OS=candidate division WOR-3 bacterium JGI_Cruoil_03_51_56 GN=CH330_01575 PE=4 SV=1 --MFDRILlFVEDK-NTPKETIIWTIALARQLGSRLIAVYIVDTNALpegkeqlslieekaWKILYEIEDDAFEQNI-KVSLLLEQGDPLEKLLTLCKSYEIQLVVLGSKSLPPL----------KLMER----------- ->tr|A0A1M3M9R3|A0A1M3M9R3_9BACT Uncharacterized protein OS=Paludibacter sp. 47-17 GN=BGP01_09530 PE=4 SV=1 -----RLLVAVGHTARSAELLVYASELAKTMHAsSIQAVYVENTYEl-tqrqRKELDYNARIAKQLGI-EFRIIS-NYDTVKGIAGFALQEHITHIVIDKPKTFNlLSLLRWGNFVINLIRNSEhIHVCIFGFD ->tr|F8E9Q2|F8E9Q2_FLESM Uncharacterized protein OS=Flexistipes sinusarabici (strain DSM 4947 / MAS 10) GN=Flexsi_0554 PE=3 SV=1 -KIINHILLCLDLSEIDEDIVHYSAVIAKSFSVEkITLTHIIQPSDLPkkdedslnevknsidemisiEFENFLKKELGENMIINIYTQIAEDEGLEIIVSNVEDMNVDMLVIGQK----YGEYRQKFHSRKPFAESDCDVLFVPEN ->tr|A7H942|A7H942_ANADF UspA domain protein OS=Anaeromyxobacter sp. (strain Fw109-5) GN=Anae109_1029 PE=4 SV=1 ----MNWIVGIDLRPLSHGALQFAAWLAANagagGADRFVPVHVLEEEHLRtmlryhhldevidAAREEAKRTLLREGRAewLGDLQIVQAvNAERSLEFVRAAAGAEAMVIGRAAAREGHRiVRLGRVARRLLRNLPSPVVVVPPD ->tr|A0A0C2D2E0|A0A0C2D2E0_9DELT Universal stress protein family protein OS=Enhygromyxa salina GN=DB30_03147 PE=4 SV=1 ----SKWAIGVELHEAHLGPVRFASALARTDEDLALGIHALPDLElLHplvnqaeakqmheKVASQITALMAQAGHNpaQVRVELVEDaEIERGLAEASVRLGVDALVIGRRANRDEDPiVRLGEVARKILRRLPVPVVVVPPD ->tr|A0A1F7MKP7|A0A1F7MKP7_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RBG_16_73_20 GN=A2W08_01830 PE=4 SV=1 ----MKWILGLDLGPRSRGALQFARWIAEAthGSDDFVAVHVLDVDHLWgvlkyhhlseiieVANAAAHRELERAWPGgsLPVIEVRQAlTVEDGLAEARARHRAEGLVIGRAASTEGHHlVRLGRVARRVLRQLASPVVIAPPD ->tr|A0A0D8DB91|A0A0D8DB91_9GAMM Uncharacterized protein OS=Thalassomonas viridans GN=SG34_18885 PE=4 SV=1 --EYQNIMAAVDLKKPpngefylDKEIIDTCVMLSEYLETSAHINHVYDPKGQElwqgnnlsllgfnmpsyispvppsqlesYHRTEFYRLIEHYAFDDTNIHLDTGIPGNRLTRNVIKHKIDLLIAGVRCHSGF----IGNTTGNIVDHVNCDILALKA- ->tr|A0A1E3G7W1|A0A1E3G7W1_9GAMM Uncharacterized protein OS=Piscirickettsia sp. Y2 GN=BGC07_01290 PE=4 SV=1 -MNYKKALFATDLRWKSFSAADQAVHVAQCLGIEdLTALYVIENRKFLSKVFYQEEEhlaycklseLASFSHI-RNYLIEEGDARKVVLEFINEHDIDLLFINAHCHSGFDR--LGSVGYALVNQAPCPVWLLP-- ->tr|U3QIX7|U3QIX7_RALPI Universal stress protein UspA OS=Ralstonia pickettii DTP0602 GN=N234_08495 PE=4 SV=1 -MDFRSILVDLSADAARSARIETAARAAAKFGGSVVGL-TATGTNlepfrgageeagqyaalaasqLHKLVAGHKEALDTLteqvsPDIPTRHIVIDAESGWALADEGR--FADLILPAPPSADADVPALLAGVAEYAMLNAGRPILLVPGA ->tr|D7A0E4|D7A0E4_STAND UspA domain protein OS=Starkeya novella (strain ATCC 8093 / DSM 506 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIB 9113) GN=Snov_21 -MSIRTVLLHAAPDSGFNDRLAFAVALARQSGAAIKGLYTLYPAGvprvgralsiyvnelvreAKEKEGGLKAQFEQAtaaAGLAASWETIEGEVASSLREAVA--FADITVVSETPYGTVDDQLAATLPEHLAMACNGPVAVVPTG ->tr|K0N308|K0N308_DESTT Uncharacterized protein OS=Desulfobacula toluolica (strain DSM 7467 / Tol2) GN=TOL2_C03290 PE=4 SV=1 --MKTNVLIGVSDSVIFREVLNRFIILPfDKAKLTITLVHVFRKATnseqllgnnyifrqierFANLLDLTKNILIQNGYQEEQVAVklietPYPTVSEGLIDQFKKGDYHMAVLGRKRMSKAEEFVLGDPCTKLIRYLEnTCVLIIKG- ->tr|A0A090LZQ2|A0A090LZQ2_OSTTA Universal stress protein A OS=Ostreococcus tauri GN=OT_ostta04g00015 PE=4 SV=1 --PRRTILCPVNDDDISAAAVKWAVkNIYRDRRDTIHLLKILPPAHWSftyayaprptrerldktemkQFVRDEAKRAIQARFgrdlamrkVPYVIDLTTGQssnvaIGELICAISEAVQASVICMATHNRGAMRRFFVGSVANYCLRNSKVPVVMIRPE ->tr|A0A1V5KQD3|A0A1V5KQD3_9BACT Universal stress protein family protein OS=Verrucomicrobia bacterium ADurb.Bin474 GN=BWY82_01878 PE=3 SV=1 ---QGPLIACVDSSGYLEPVIQHAIWWNSQISaSGIVVANVSDLRCFDqpvvnelggalgvqpfqglvaelqriesmrveTIRSRATALVEASGGGiRWRFDNRMGVPADVIQPFQS--CALGVVLGKRGDGyGYASEHLGSNLDRILRSSQLPCLI---- ->tr|A0A1G8E6X9|A0A1G8E6X9_9BRAD Uncharacterized protein OS=Bradyrhizobium ottawaense GN=SAMN05444163_0660 PE=4 SV=1 --DFGHILIAWSGSRESARALSESIPFLCLAEEVTVVVVTSEHPTEEEAVFgvDAVNHLRHHEIHAALHRIKssHKEVATQLMAEAERRKANLIVMGGYGHLPLQSGYRRFLRSR---SRSRPCRYGDP- ->tr|A0A0Q8B4A0|A0A0Q8B4A0_9RHIZ Uncharacterized protein OS=Rhizobium sp. Root564 GN=ASD74_20840 PE=4 SV=1 ---LGrSIAVLWKDDEETRSCLQKAALWLR-SAVTISILVER-AGDIEA-AVAFLGIVEPSPH-A---HIetGLVKHGKDFIEKAKILGADTLLMGAYRHGQFVEAVFGGDTKAVLDGTDLPVFLSH-- ->tr|A0A1R1SC18|A0A1R1SC18_9ACTN Stress-inducible protein OS=Streptomyces sparsogenes DSM 40356 GN=SPAR_29331 PE=4 SV=1 --QLRPVLLGLDTATPDPALIEFAFEAAARRAVTLRVLHGWNPPYYYayamapdpavtetvaqadaaALAETLQPWRQKYPDVVVVAESRCCSPSLALIDASR--EASLVVLGRRIRRSSVGAHIGGVTHAVLHHATAPVAVVAHD ->tr|A0A0U4C8W9|A0A0U4C8W9_9BACT Uncharacterized protein OS=Hymenobacter sp. DG5B GN=AUC43_17660 PE=4 SV=1 --MKPTFIVLTDLSPAAHRAAHLAALLAAPVGGQLHLLYLEQEPVFTpemgmvvipedfytqekLEADAALAELARTLPVPATASACRGSLHDVLGELISERQPQLLVMALYEEHDLLDALLLDQALPVLRDSGLPVLLVPEC ->tr|W8F4L1|W8F4L1_9BACT Uncharacterized protein OS=Hymenobacter swuensis DY53 GN=Hsw_1931 PE=4 SV=1 --MKPSLVVLTDFSPAAERARAYAAALAGPLGAELHLVHVVAPLPPIptesgvmlmpptdaryvQETRQSLAQVAAGLPVSATAELLETTWDAAIEQAIEQYRPQLIVAGLSATHGWLDEWLSNRTRSLAHQTGCPLLLVPES ->tr|A0A142HKN7|A0A142HKN7_9BACT Uncharacterized protein OS=Hymenobacter sp. PAMC 26554 GN=A0257_21670 PE=4 SV=1 --MNPSLLVLANVPEAAPHMARYAAALGQPLGLRLALLHCGLCAPLPepksmgeeaalpsrneVQTLAALRALARRLPVPAEVAEAGGQLEDDVAAAANRYQPLLVAMGLGPRQHLLDELLRTQVLPVLRATGRPVLLVPAA ->tr|G6EK59|G6EK59_9SPHN Universal stress protein, UspA OS=Novosphingobium pentaromativorans US6-1 GN=NSU_4730 PE=4 SV=1 --GFQRILIAWKDCREARLALTAALPFFCRAH-TIMIVGLGEE-APTGCLEAVQGYLAAHDIDAKYFHAAapKGNGARWIAEFAEREGYDLLVTGARARGRWKERIFGGMTEDL-RAMNLNWLLAN-- ->tr|A0LLQ4|A0LLQ4_SYNFM UspA domain protein OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_2678 PE=3 SV=1 -NETGKVLIAMEDAPESRELTAYAAEfVAPSRRMRFTFLHLMPPVPPTfwdnghilgsaerkdrqsriekwrsewmdrvsKFMSDGKELLQRQGTPgtNLDTLVLptKLGIARDLLNEIAEHQFQMVIMGKKSFHERKPFLMGSHASKVMQNVKCVVL----- ->tr|A0A1F6GAF6|A0A1F6GAF6_9PROT Uncharacterized protein OS=Candidatus Lambdaproteobacteria bacterium RIFOXYD2_FULL_50_16 GN=A2527_07940 PE=4 SV=1 --MKRQILVPLDSSAVGREVIHLADQWAHLFDAELVFMQVNPVLRDVADQDLLESVILSERVTaPYRAIASYGNPSQEIIEQEKVVDPWIVMMAAHSHSMMARILLGSNTDYVVNQCKSNLFVYKRS ->tr|A0A1W9S094|A0A1W9S094_9BACT Uncharacterized protein (Fragment) OS=Candidatus Coatesbacteria bacterium 4484_99 GN=B6D57_04000 PE=4 SV=1 -EKVKRIVYAAEDSADAKYALSILPAFQDEFNVHIVALHVI-KGSPQvfehlSGQIFLDELLKDCPIKIERKIIVAESVEEGIINFVE--PTDLLVMGLGSSSFLERILFSSVSEEVSERLEGPVIMIS-- ->tr|D0LX45|D0LX45_HALO1 Amino acid permease-associated region OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_3585 PE=4 SV=1 -ADARRVLVPIGGrGGQHEMRARLLGSIVRTAPREVVFLQVVAEGAGADEIEQARRQAESLvrwnlTGQHEVAVVAASDVATAVVEAAA--NCDLLVMGLQAErnpfgVGRGRAAFGELSLEIARRASCATILLSG- ->tr|A0A0P8AKV1|A0A0P8AKV1_9BACT APC superfamily amino acid-polyamine transporter OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_04845 PE=4 SV=1 -SQARKILIPVAGfDKHDLLRARIAASIWRSYQPEITFQQLVPAGVSKKELRTQRRLLHRFaeeiiPTGFKTSIKQSTDIPATLVHEVS--QHDLVIIGLGR-LLPGDKAFGPIPMDIIKKTNTAAIFISH- ->tr|Q7UFY5|Q7UFY5_RHOBA Cationic amino acid transporter (Cat-1) OS=Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1) GN=RB8254 PE=4 SV=1 -DQSQQILVPVGGrGGHDYLLTRLLSSLSREQQRQVKFLRVIPTDTLRADQKRIRKELDRTtrvnaGRVCEREVVRSNDPVKTIADRAG--TAGLIILGAQR-LGPRQKLFGDFTRKVALESDCPVIIISR- ->tr|A0A1V4QQ77|A0A1V4QQ77_9BACT Uncharacterized protein OS=Planctomycetales bacterium 4484_113 GN=B1H03_06510 PE=4 SV=1 -PVVKRVLVPVANPVQARLSMAVAAAVAGqRSDMQIDLVNLVPVGTPAEVREQRLQELHDRmlrvrgelppdsplEEARDQLLVegttynlvqyEAESVVKKLAALST--NYDAMVIGGTSGr-VWRSHVFGRIPRYVAEHAKCPVVLVKM- ->tr|A0A0E3ZFB7|A0A0E3ZFB7_9BACT Uncharacterized protein OS=Pontibacter korlensis GN=PKOR_10120 PE=3 SV=1 -HSLRRILYATDFDKTDAQALATLLQLFEPFNPEVLCAHIGTEGSETEdshKMEQLQARLYTaLPNHNLQFVILPsSdDVADTLQEFVEREQLELIAINNHQRTLFSSIFKPSLSKKLVLEAHVPMLIFHSP ->tr|A0A1V6HFL4|A0A1V6HFL4_9BACT Uncharacterized protein OS=Bacteroidetes bacterium ADurb.Bin041 GN=BWX63_01536 PE=3 SV=1 -HGFDNMLYATDFNDEDVYDLQRLIDLISNYNPVIHCLHINFDADHSAdieKMESLKSHFREkSYYGKLIFKVIEDvDFLQGINNYVSENKIDIIAIVNHRRGFLKRLFTKDHTRELLFHSDLPLKIFPGV ->tr|A0A1Q9TJM3|A0A1Q9TJM3_9MICO Uncharacterized protein OS=Kytococcus sp. CUA-901 GN=BJF82_04635 PE=4 SV=1 --PVTSLLFVLDAAPGHHVAREYVVDLAVHRSATVHLVYVALESTRttpmavnpdqrrrlaqeaQAAMDDEVTRLADLGVTDVQTHLRAGDTASHVLGLADDLGVDLVVIGDQADSRVLRALVGErPATRLARRAPCSVLVAKEG ->tr|A0A1M3ICR5|A0A1M3ICR5_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 43-93 GN=BGO70_14415 PE=3 SV=1 -----KVLIAVDYSQQTERVLEAAKVLigARVPQPDVTVVYIIDEMWLstatggegevfntlRDDSKKINELAIKHLGNNVVYLEEYGIPTVKINEVLDSTPHDLLVFGMKGRSALADVFMGSMASHLLHRVKTPMLVVP-- ->tr|A0A017HER8|A0A017HER8_9RHOB Uncharacterized protein OS=Loktanella hongkongensis DSM 17492 GN=Lokhon_01615 PE=4 SV=1 -KHMKTIVAATDFSKAGNQAVLRGAAIAAHTGGRLHIFHAANFRIAAEqkahfnalvegYFDTLRARIQCRYGSSLQVSHTYSGDWQDIYAILKRKKANLLVAGQHVHPNGIDMFHGTFVERLTADCPVPVLV---- ->tr|W5WFI6|W5WFI6_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_3565 PE=4 SV=1 -REVGPITVGTDGSYWGGLALQWAARYACTLGTKLRVLRPGTNAELPADVPLDLGLthtMHLYPLLPVICTPITVDPLAEFAEAST--GSELLVLGCRGHLHRCTIGLGSLVLPTVSTAHCDVLVVRG- ->tr|A0A166RIC4|A0A166RIC4_9EURY Uncharacterized protein OS=Haladaptatus sp. R4 GN=A4G99_15750 PE=4 SV=1 ----RNVLVHLTGSEIDQCLIREAGTYVTGTGGKLVLVNTMAPNEFMErqqahaqidhlptyticqaeescrqhALKRGRQALVAFGI-DYTAVGMVGRETDSLLTTAQQYDCGHLFLGDQQQSLLRRFTALSFSQVITRKFDGLVTVLRS- ->tr|A0A1G7RID8|A0A1G7RID8_9EURY Universal stress protein family protein OS=Halorubrum xinjiangense GN=SAMN04488067_11564 PE=4 SV=1 ----NNILVAVDSTDANGYVMERAIESARLEESTLVVAHVMSTAQFDDhlgaigtipelrkdgatftvdqareraravATRAARAAVGDLDI-AYVTVGAVGQVDATLLEIADQHDCGTIMLAEQRSWWRRRLGWGD--KRLARSFEGRVIRVPR- ->tr|A0A101DZK8|A0A101DZK8_ARCFL Uncharacterized protein OS=Archaeoglobus fulgidus GN=XD40_1966 PE=4 SV=1 -----KVLLIVDDSELSDKATECAIDLHLsGLKSKIYVFYIKDEEPVAfpseglerkkyapmvskaeKVIIQTTEKLKDAGIDYEVLGYHIGIADEEIKRIEETFKPDIIVYGAEKKSRFRKLIQGGCEENIVFETDAPVIVVK-- ->tr|O30112|O30112_ARCFU Uncharacterized protein OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) GN=AF_0125 PE -----RVILVIDDTDCGRVAAERLVFMARaGFRGDVFVVFGKDIEISPiasyekemkiytslrvkasKFVEFYRERLEEAGLEVKQVKIILGNVSEEVLRLEKLLNPDLIVFGMEKRGFLKRLLRGDPYKEIIYETKAPVMVCK-- ->tr|D2RFF7|D2RFF7_ARCPA Uncharacterized protein OS=Archaeoglobus profundus (strain DSM 5631 / JCM 9629 / NBRC 100127 / Av18) GN=Arcpr_1807 PE=4 SV=1 -----DVLVVVDDRWN--RVPESLK-NLGkRFKAKLHLLFVRNLQITPevltelekkysslkekalKKLQSLAEELKSYGFGTDIVGVHYGIAHERILRESERIKPDYILVRARRRPRLWRILGDYYYDDLFRSSKIPVLVGR-- ->tr|A0A1G0CM58|A0A1G0CM58_9FLAO Uncharacterized protein OS=Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24 GN=A3E30_02200 PE=3 SV=1 --EIKNIVVPIDLTKESLQIVSPAGDLARIFDATVHVIGERHNDEGLSQQTKnrvllIRNKYDEKGAKcEVHLLKNGGSYSKKIMQYVSEVGVNVIAIAYHSESLLP--QFDSFAQSLITNDLKlPCMILAA- ->tr|A0A1Q3ZEK1|A0A1Q3ZEK1_9BACT Uncharacterized protein OS=Flavobacteriia bacterium 40-80 GN=BGO87_08685 PE=4 SV=1 --AIKHIAVPIDISSESLQITNIAADLGKMLNAKLSVIYEPVHDFTLNNRMNirlgiVRESYDNKGVDyEISELKGSGSSLKKINHFMADNECDLVAIAYFSNALFP--QFDTFAQNLITNKQKlPCLIVSA- ->tr|M1PR57|M1PR57_DESSD Universal stress protein UspA-like protein OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=UWK_02326 PE=3 SV=1 ----KKFLVPVDGSVNSLMAIDHLCHIFAeRTDIEICLFHCtaifgkeihCKPELFYKKWGKDwsdthlsgtdclfngpQQLLLNAGIPEKQIQILPEstdiEEAHSIIREAKKRDCGTIVMGRRG-KATSKGLFGGVSDRAIKHFQ--------- ->tr|A0A0U5J571|A0A0U5J571_9GAMM UspA domain protein OS=Thiocapsa sp. KS1 GN=THIOKS11770032 PE=4 SV=1 ------LHFAYDGSINGDWVSHYAVQLASALHdRTLRLIHVRSEQILPAMLEDKLGRILRECAHqRVRLIkeilpPAEHTLETAIRSAVPAGPEHFLLCGTPARAPGHGALRETIAGRLLRSGHCNILAVR-- ->tr|A0A0A2HTT4|A0A0A2HTT4_9DELT Uncharacterized protein OS=Desulfobulbus sp. Tol-SR GN=JT06_10255 PE=4 SV=1 ------IYLAYDGSINADWVSRYAIRIAATFHnRRIILIHILDHSASRRRIDEKIAAIARECEVhGIECRsvihDLDRDVFSSLLRLIPAGDNSYCLCGARIASRGRGFLAGTVSERLLRSRLFNVMAIR-- ->tr|W0F7U1|W0F7U1_9BACT Uncharacterized protein OS=Niabella soli DSM 19437 GN=NIASO_09330 PE=4 SV=1 ---PEHIIGATDGSAESMHALTQFCKMFPQYsALPAKFVYVKNEHNKKIPDRRLLKEYVSLHFKEAEILKLHWDHQKLFTTWLGCYKNALVVTGAFGRSALSNLLQKSFAAQVIREQAARVFIAH-- ->tr|A0A1A9I2B8|A0A1A9I2B8_9BACT Uncharacterized protein OS=Niabella sp. BS26 GN=A8C56_07420 PE=4 SV=1 ---PERIIAAYDGTDESMHAIIQFCKTLPLFqSLPAEFVYIKNENNDRIPNQELLQEYINAHFENAAVLKLHWEPGRLLTRWMECHRNPLLITGAFGRSALSNLLHKSFAELIVSKTGCFVFIAR-- ->tr|A0A0N0UYA2|A0A0N0UYA2_9BACT Uncharacterized protein OS=bacterium 336/3 GN=AD998_09710 PE=3 SV=1 --NIKHIVFASEFEQEPDKVMQELNDWQSITGAKVTLLKVNHPSFTLNreemesslNEFALRNHIKNYGVD----AYTDIDPTHGIIHYAEHNKADLIFVGTDFYKGLLERLWHRRTQVaeeVATHTAIPVVSYH-- ->tr|A0A136PAP3|A0A136PAP3_9BACT Stress protein UspA-like protein (Fragment) OS=Chlorobi bacterium OLB5 GN=UZ05_CHB002000538 PE=3 SV=1 --EFRKIVFATDLEHKARKVINQAWAFLKMYNAKIDILRINTLKDSIRstyAIGQMRNISKKYNaefdFV----LAEAKTPEEGINEYCVKTKADLLVIGVHRKKGFKRLFTDRISESitrT-------------- ->tr|A0A147JXQ8|A0A147JXQ8_9EURY Uncharacterized protein OS=Hadesarchaea archaeon YNP_45 GN=APZ16_02575 PE=4 SV=1 --MFKTMVLCVTEATP-EEVVKVAIRLCSK-ETKIYALHVvrllseFSKKEALERFSWVIDAFERAGLKSQLEIIESTDVGKAIVSFAKKNACDVIVTGTIPRKGLLGAFTESISDYVIKYAPCTVILVRKS ->tr|A0A1H5VWQ1|A0A1H5VWQ1_9BACT Nucleotide-binding universal stress protein, UspA family OS=Bryocella elongata GN=SAMN05421819_1348 PE=4 SV=1 ---PRHILHPVSFEGGYEVAVSQVSELAKAAEAHLTLLHVLDDSPENKvnpgrILQWAhhalgqLATASGLLPEHVHLQVVEGRVADQVVRIARQAAADWIVFATDEQTS-ASLLNESRSFRVMAEAECPVMLLRS- ->tr|A0A1Q4GFY7|A0A1Q4GFY7_9PROT Uncharacterized protein OS=Thiobacillus sp. 63-78 GN=BGP20_09345 PE=3 SV=1 --GVAVDL-TERSAATIRKAGELApnatTCLLHALqAPNHERLrqlgasdeHIKRSRSEFydravreigkliadrqderisrVVELDYPPAMIRRWTEK--------------------LHFDLIVMGKRGGRLGS------VVRHVLHNSASDILVVG-- ->tr|A0A0S8F6W2|A0A0S8F6W2_9GAMM Uncharacterized protein OS=Thiotrichales bacterium SG8_50 GN=AMS22_00710 PE=4 SV=1 --MSETVLTIIELDNYPEEVVARAAWLARLMNCDLELLLCDPTTSFLsevfiissevrdlakdieeaqkTTLLDLAKTAESSGL-KVITHISHERPVaDGIISRAMDLEPMFVVKGTHYHSPAERATFADTDWQLMKKLDYPLWFVKP- ->tr|R9AHQ6|R9AHQ6_WALI9 Uncharacterized protein OS=Wallemia ichthyophaga (strain EXF-994 / CBS 113033) GN=J056_003901 PE=4 SV=1 --PSRKILLAFNGTEEAIHTLNYLKNKILRNGDHLFIAHILEMPADDQqthesnliqlkqirdhvldNLRAISNDILHSNLHITTTLLVinHADAKIAICRIADHHAVDLIVVGRRRRDEGGGGIPGACSTYILKQSRNPVLIVNKS ->tr|A0A1B7UQT5|A0A1B7UQT5_9GAMM Histidine kinase OS=Rheinheimera sp. SA_1 GN=A5320_05625 PE=4 SV=1 ----DKLLVLISNQRDHEYLIRIGRRVAEKRQMPWLVVWVDTGKlqyqSMQQRLQSAFALARELGAQ--TDILRGPSTLQMVLPYIVEHRINSVLVGAGTRRPWQ-PWRKPLYQQLINSgLPLEVSVYRAD ->tr|W1FW48|W1FW48_ECOLX Universal stress protein F OS=Escherichia coli ISC11 PE=4 SV=1 --MYRSILVPIDISETdlTRHVVPQVQAHA--KTAKVHFLAVIPTVPFYaslglaystefpdrsGLQAKASEKLEEIikqfniPAGRSQTHVVLRPAEGSDPQVGRGGGR--------------------------------------- ->tr|A0A0Q2UM69|A0A0Q2UM69_9RHOB Uncharacterized protein OS=Loktanella sp. 5RATIMAR09 GN=AN191_16685 PE=4 SV=1 -----MISILTDLHPRSDRVLDRSALIADELSSDLDIVHAINPDSdfaeatakleapqFSDDDGNLRTALAIKNPIRMQWVGLRGAAPDSLVTYIADKRPDLIIVGTGREFTLSKLAIGSTVDRIVARASPAILIVK-- ->tr|A0A1Q7JC59|A0A1Q7JC59_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_1_40CM_4_69_8 GN=AUH78_13495 PE=4 SV=1 -SPMQSCAVAFDGGDTSRRALDLAARFASIFESTVHVIHATPDHEAGVRVVGTAEAVLSMLGVSFVTHIEGGSPGEVVARVIARTKCDALFAGAHleRRSGRPSQPVVSHAEEILRHTDIPVVIQP-- ->tr|A0A1Q6WTY4|A0A1Q6WTY4_9BACT Uncharacterized protein OS=Gemmatimonadetes bacterium 13_2_20CM_70_9 GN=AUH07_00350 PE=4 SV=1 -SPMQSCAVAFDGRDTSRRALELAMQFASVVEGTIHLIYATDDREAGLKVVGVAEATLSMQRVAFVTHVEPGKPGEVVARVIKRTHCDALFAGAHmtHQQGRPSAVVVSHAEEILRHTDIPVVIQP-- ->tr|A0A133VR25|A0A133VR25_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382M17 GN=AKJ55_00305 PE=4 SV=1 ----KRILIPVGYKGYdyTKR-LSVTAKIIKETGAECVLTHVNQEEESeeeaEEILQSSKELMRNMGVNSETKILRNEDISEALIEESS--DYDLIVLGPTNEYVFSRYLFGWMTDEIVNNVECSALVFK-- ->tr|A0A151AA93|A0A151AA93_9EURY Putative fructoselysine transporter OS=Halalkalicoccus paucihalophilus GN=HAPAU_36010 PE=4 SV=1 -----QVVVAISNPETAKRLVTFGSRIARHHNGEVLLTTVVTVPVQtpleeganyitnqRELLAEAMRYVP-EDIPAHRVVTIGRNVGRSIVNLAQERDSELVILGWRGRSKPTkPPILGTTIDYIVENTPCDLVIAKTE ->tr|I0A231|I0A231_FERFK Cationic amino acid transporter (Cat-1) OS=Fervidicoccus fontis (strain DSM 19380 / JCM 18336 / VKM B-2539 / Kam940) GN=FFONT_1 -----RIMVLLP-PEIRTNLIQLASDIAKAKNGEINLLKIIKTPYQlsvkdyrneavkkdVRSLKDIIDHLNETGIHARYSIKAARSKTEAIIASIDEERIDLLIMSAEDAMKLN---------SVMRLSTCDILIVNTE ->tr|A0A075FWJ2|A0A075FWJ2_9ARCH Cationic amino acid transporter OS=uncultured marine thaumarchaeote AD1000_72_F04 PE=4 SV=1 -----RIMIVFD-KRNATKFYKIAKAISEQNDGEITVLNIVNVPRQtplslshgigdngLKAIEEFKRAIP-GSLRNRFLVRLAHDPTEAILSTAEEQDINTMLVDF--SFLRNNR-------KLLSLTTCDIIGIRLR ->tr|A0A1J4WK74|A0A1J4WK74_9BACT Uncharacterized protein OS=Parcubacteria group bacterium CG1_02_39_15 GN=AUJ31_01070 PE=4 SV=1 -----RILLPIYPDTNWKDLLNLALVFAKQKDAEIFILSVRQIPLPlpliaeeeeieddKRFLEEALNLCKDCGVNVHAVLMTSRSISEAIISMIQREKPSLLLMGWKGYARLTkagQKIFGRDLDIILREVNCDLIVTRLE ->tr|A0A1G1ZN13|A0A1G1ZN13_9BACT Uncharacterized protein OS=Candidatus Harrisonbacteria bacterium RIFCSPLOWO2_01_FULL_44_18 GN=A3A16_01580 PE=4 SV=1 -----RILLPIA-PHLSleeiKNLAENAFVLTSKYDGELVIVTIHEIAAAlplnpamieegllqreKEIFAQLhqwveeynkKTGPEVKNINFHSLILIGRDIVDVLLDVIKMEDCDLLALNWTGYVEGQDAILSRKIDRILRESKCDLLVVKNP ->tr|A0A1G2PFL6|A0A1G2PFL6_9BACT Uncharacterized protein OS=Candidatus Terrybacteria bacterium RIFCSPHIGHO2_01_FULL_43_35 GN=A2828_04165 PE=4 SV=1 -----RIVVPIVGTASLheaaLRLEVVKAMAKRYLPATIYVIGIHNVPPSrtfesvikhpngqesgeldhehsfvHEVAKKIKESMP-DDVDVDASIRLarSGGEADAILNVVERYHADLLVLGWRGWTKTQGQRLGSTLDPILYRHSCDMIIVKQG ->tr|A0A1F3Y6S1|A0A1F3Y6S1_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 GN=A2603_16235 PE=3 SV=1 -RPIRRILFPSDFRSDSKRVLDRVIGLAGQLNAKITIFHAATmprageiplskpaavrfedleiPPAWRDYHEQRRQEAEAFTDHIRVSRVdaealfdSSGQPVGEVIQlIAAAEDVDLIAISARS-GPISTYFKGRITQRLIRQAHCPVWVLHEN ->tr|U2YNY7|U2YNY7_9SPHN Uncharacterized protein OS=Novosphingobium tardaugens NBRC 16725 GN=NT2_10_00550 PE=4 SV=1 ---MKSIIIHIGLDPEVETRYQAAVDVVQAFQGHLTCVQTATpVDAYmpvdpfggaafmadsyerakqaeEETRVRLEERLRTEGI-SWDWHCHAGAPARLLANHSW--LSDLIVVSAPPANWAARLGTPPVAADVAVNAHAPVLVMPEG ->tr|Q2GAV5|Q2GAV5_NOVAD UspA OS=Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CIP 105152 / NBRC 16084 / F199) GN=Saro_0571 PE=3 SV= ---MRSILCPVDASETLDDRVETALALARATKGHVTF-QISTpFAQMavwepfggatisaaaiadaregdEKLQRQLDARMASQDV-PFDVTIEDSGHVEAAAAAAR--FADIVVDTLDHP----------SLEELVLGLRSPVLAVPRG ->tr|Q0FZV1|Q0FZV1_9RHIZ Uncharacterized protein OS=Fulvimarina pelagi HTCC2506 GN=FP2506_04656 PE=4 SV=1 -RMYTRILVPIDLDHRekLEKAMKTAADLAKHYQASIVYVGVGSSAPSgsahtpeeykKAVERFAKSQSDTYGVSATGEAVIVHDPSveldRAILKAIERNGSDLVVMATHV-PGIPDHFYAAHGAKVASRASVSVMLVR-- ->tr|A0A1H8EIT7|A0A1H8EIT7_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Pseudorhodobacter antarcticus GN=SAMN05216227_10093 PE=4 SV=1 -SMYKHIMVPVDLAHIdkSETAFVIVADLAKLYDAIVTYVAITSNVPGaiahnpeefaHKLADFAKAQSDQRGHRTAAHSVVSSDPTvdldKKLAGTVDELGADLIVMATHI-PNMADMLLPSHGGALARHTGASVFLVR-- ->tr|A0A1E7QGD3|A0A1E7QGD3_9FLAO Universal stress protein OS=Salegentibacter salarius GN=BHS39_10245 PE=3 SV=1 ---MKNLLVAIDRRQDAEQLMTQAIKIAKLTDAKIWIMHVTEADPDDflareagpqyvyekrakerknasLEIQKWVEEVKEKYSIDIEGLVINGEVTKSIKNIVDERNIDLVVAGHKKKSLLYGLFTANKKKDLIDDLKVPLLAIP-- ->tr|A0A1I7GG94|A0A1I7GG94_9BACT Nucleotide-binding universal stress protein, UspA family OS=Pontibacter akesuensis GN=SAMN04487941_0989 PE=4 SV=1 ----KRVLVPVKFDKAGKKLLRYAGHLANALGAELLLLQNSHTNELtftqqssflqqlrtFSMRILGEEQMSGAKQVPFQCVVRPGQLRECINVIIREYAIDMVLMETCVLHQEEGHNDPDNAAAIMELVKCPVMVVPCT ->tr|I7A1Y7|I7A1Y7_MELRP Putative universal stress protein OS=Melioribacter roseus (strain JCM 17771 / P3M-2) GN=MROS_2021 PE=4 SV=1 --KFNKICVDVDYTPLNEIAVKKAYKLALLENTEeFILVREFQVPGLAitvsdggdsedteskrliwqkeeeMKLKLFAEELNLTEIK-PKLVCRYGREGWELQQYVRESGSDLLVVALPPNkLKFFDRIFKHDLEFIFSQLPCSLLIIR-- ->tr|A0A090WQW1|A0A090WQW1_9FLAO Uncharacterized protein OS=Algibacter lectus GN=JCM19274_1067 PE=4 SV=1 --PCQHIVVNGLKDPKTESTITAAFYVANQLKAKkVTIVEEINEEQVTvkvdddkslrratiikeriklrenSRIKEIISHIPVectTEKS-IKLQPIFGKKGYSIGHYAQIMRADLLVMNAPTKMTFWDRLFPHDIEHILTELPTDVLILQ-- ->tr|A0A0F2N8L5|A0A0F2N8L5_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium BRH_c16a GN=VR65_24145 PE=4 SV=1 --TFKRIMVDCVDHPKTLHTLDTAFYFGSQTGAGeICVVGEVDPAGLVmalsgdttqerdlvkeqlvieaeENIKEKIASCNTRGMH-IQNSVLFGRPGFMIRKFAEDRRANLLVINSPDSrYGLMDRIFTHDMEYILEHLPCHILIVH-- ->tr|C0BIZ3|C0BIZ3_FLABM Uncharacterized protein OS=Flavobacteria bacterium (strain MS024-2A) GN=Flav2ADRAFT_0805 PE=4 SV=1 --PCKHIVVNGFDSPQTHETVEAAFYVGTSLNTEkITLVEEISESRVAiavnddrslrkatlrkekidreekLRVTDIVEKIPAtkrDGLK-WETQSIFGRRGYSIGHYARVVRADLLVMNAQEERRFYHRFFPRDLEHILAELPTDVLIIH-- ->tr|A0A1M7ZGM6|A0A1M7ZGM6_9BACT Nucleotide-binding universal stress protein, UspA family OS=Algoriphagus zhangzhouensis GN=SAMN04488108_2991 PE=3 SV=1 --EFSKVVINGTQLEITPVVIEQGLEFSKTVKADqVSILNEIKMYGLQmgtasedsedeiaqtrrqlvqneiDYVEQILQKLDKGNLR-INIKVTGGKWAVELARFCEKTDADLLVVGDE-RkLNFFDRIFPHDLEELLSTLPCNLLIVK-- ->tr|A0A1Q7S457|A0A1Q7S457_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium 13_1_20CM_4_55_9 GN=AUG90_00050 PE=4 SV=1 --PLRRIVFVANYSDHAQRAFQQALKLAAAESSErLYAVRVYTTFDEVrattfvdngdgtprprtfdeedAALEKFVLAAGETEVP-IEARCIRGNTGFAASDFIDSVEADLLVVPVHKSe--TSAERLPNHLAWIADVIPCNLWLIR-- ->tr|M0CQ39|M0CQ39_9EURY UspA domain-containing protein OS=Haloterrigena salina JCM 13891 GN=C477_00985 PE=4 SV=1 --MDRSILVPYDGSRRSQSALRYAADVF--DGETITALHVLDPFATipdsekqvRERYERAQDVLETVPAVaderstTISSEFVYGHAIHAILRYADLYTIDRIVIDGSYRADTADAPLGNVSEALVRRTRAPITVLRSA ->tr|A9W3K8|A9W3K8_METEP UspA domain protein OS=Methylobacterium extorquens (strain PA1) GN=Mext_1765 PE=4 SV=1 -PAMKTLLVPVTLHDALPSVFATAVLVARRFGSLIEGVALRPALAEYvpvdmvggmtwlrdeeadqAEAQDAGQRFVaameaaglprrepgascapdavPNAGPRYRWQPDVPPGDAFLGQYAR--LFSATVVGRPGADDGSP--RMTTFETALFESGRPILLAPPA ->tr|R5QNR7|R5QNR7_9PROT Universal stress protein UspA and related nucleotide-binding protein OS=Acetobacter sp. CAG:977 GN=BN820_01398 PE=3 SV=1 -SGFKEILVCSDATENIEATLETALLAARRFNSHIDAVHIHKEPTCVlpvpvvtsdmagfvvndvvtaeetalaETADKTRRIFEkfiekedirpqaepdlNSNEVTAEFRELYGSADEILSWASR--VSDLTVLPRPDTEALSEDA-FEMMNAVLMESGSAVLVSPLT ->tr|B8IKU8|B8IKU8_METNO UspA domain protein OS=Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060) GN=Mnod_1305 PE=3 SV=1 -MPMRCLLVPTGPDTDPRPRLDLALRLSDRLKAHIALTILCPSAEDVlasipevaiaagvtrerleqetrEAIEAARIAFDawcagadvvnrpaddiCPGLEDASFTVRLGPIDASLARAGR--LSDLILVDRPDWSDPFAAV---AFDTAVFATGRPTLVVPPA ->tr|A0A1B9Z0S7|A0A1B9Z0S7_9BRAD Universal stress protein UspA OS=Bradyrhizobium sp. LMTR 3 GN=LMTR3_15715 PE=4 SV=1 --MFRNILVHIPSERPVRPVIDVAVSLTIARRSHLDAVAIGYESMGAagmiaegggaavaavmgaeqeraqERANAAIGVFEieaklani--AYGIRTFTAIPAEAGQTIGALSR--LYDMTIVLQPDPVKASY--DNEIPQQILFNSGGPMLMVPYI ->tr|A0A1N7MBT2|A0A1N7MBT2_9PROT Universal stress protein family protein OS=Insolitispirillum peregrinum GN=SAMN05421779_10410 PE=4 SV=1 -TGVKTLLAVVPDVEGGLPTLETACIIGRDLACHVRVLHVRPDPSSAlplmgeamsgamidqmmatcekegtARAVRVRGIFDqliarydipqtdeppGPSEMSAAYIELIGQEDEAAVSYGR--MADVVVIGRPQDG-DDEPALQATLNAVLMETGRPVIVAPRQ ->tr|A0A1N6L8T9|A0A1N6L8T9_9BRAD Nucleotide-binding universal stress protein, UspA family OS=Bradyrhizobium erythrophlei GN=SAMN05443247_10475 PE=4 SV=1 -MSIKRILVPLPGSANHTGQIETALSAAKALGAHVQALFISQPPPVTrapggltvtemgrtvtapsinwhaeereRTARDAREVFVqacarvgipmlsandePGSPLAASWRKAEGSYVEIAVQRAA--AFDLMVAASA--T--VMESLVAIAEQSLLRTRRPVLLAPAR ->tr|A0A1U9KTZ2|A0A1U9KTZ2_9PROT Universal stress protein UspA OS=Neoasaia chiangmaiensis GN=A0U93_04155 PE=3 SV=1 -NDIRNILLPLNGNGDIDAALQLGLLYAKHFKAHLSAVTIGDDPNETaalageglsgsminemmaaaehesqRRLLQVHLKFDnfvrehnvanrrnalpsdlpPNGQVSASLETLTGSEHEAVTWRAR--LADMTLMPHLAKNDDAR--ASETLHAVLFDSGRPLVIAPPK ->tr|A0A1X7DKL8|A0A1X7DKL8_9PROT Nucleotide-binding universal stress protein, UspA family OS=Azospirillum oryzae GN=SAMN02982917_0648 PE=3 SV=1 --MYRKILVPLSNAAgSMDAALDAALFIGRVFGARVEVLYARPSPENLilvlgkgfagtmlenamrevqakiaRDCQAAHERMQghlrqaaaAGRDPEIVWREVDGPADKTIATEGR--FADLLLFAKPKHDGVTDNVWRSMFDAALFGTARPVILTPFT ->tr|A0A1Y5EEI4|A0A1Y5EEI4_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium 46_93_T64 GN=A9Q83_02710 PE=3 SV=1 -MSIKAILVPVYGSDtgCDSSALNSALTFSERFSGHVDALHVKRDPRAAasfvgegmttsmiesvidmaekdgqRREKSAALLFNelcsshgtviagdekisASTASTARFIMRSGNQEDLLPEYGR--MFDVIVVCKKTK--ERSSDNDHVINSAILETGCPVLVVNDA ->tr|A0A1J4XZE6|A0A1J4XZE6_9BACT Uncharacterized protein OS=Candidatus Marinimicrobia bacterium CG1_02_48_14 GN=AUJ47_03500 PE=3 SV=1 -----KLLLCVDDSNRTRLAVKTAAVVAAALNLEVVVLTVSKTTRFgpgyTAAHNWAMDYLAQKEI-KHTGIKRTGDPVTTFINEQG--TDKIIVMGSSSGS---------------------------- ->tr|A0A1Z9NGG4|A0A1Z9NGG4_9BACT Uncharacterized protein OS=bacterium TMED217 GN=CBD77_03740 PE=4 SV=1 -----RVLLPINNEDGSMKAAKYGIRVALAYDIGIDILTVSNDQKSindeNKQVDKIKKIIRRSGV-EYVHEKEQGNTVEKVIEKAG--DDKIIVMRSSDMS---------------------------- ->tr|A0A1M3MSW4|A0A1M3MSW4_9DELT Uncharacterized protein OS=Myxococcales bacterium 68-20 GN=BGO98_23735 PE=3 SV=1 -RPYRHLVVAIDAASDLRRLLEAAKIVA--PGAQLSLLHAYEDPYETgllldgsshanlragrtqvrrEARAALMPVLAKAGLEQYEVLLRNGNSRRVLeFEDRERSGRDALFVLERERSVVEHLMSGGVCRWLIARGESDVLLV--- ->tr|A0A0Q9EUN3|A0A0Q9EUN3_9GAMM Uncharacterized protein OS=Lysobacter sp. Root96 GN=ASE45_05555 PE=4 SV=1 -AMFKDILVPQLWGDISMAALRVACSIAVPLQGHVTALVGGSVASsiADareyrpagdyrsmcdslevtadEVARGIEDELKFSGV---SWGIRRnsaywLTASEIAIRHAR--YADLLVIEQPQAGLsPRRRFFSE----VLSGAGRPVLLVPDS ->tr|A0A1Q6XW91|A0A1Q6XW91_9BACT Uncharacterized protein OS=Acidobacteria bacterium 13_2_20CM_58_27 GN=AUH13_16020 PE=3 SV=1 -AELGEIIVFIDGHTEAPSILEFAGLLAEEHGAHLIGVFMQPAPKvttaQTfargkgirevmqvqeqeigGIEAHHRALFEDTLRR-HAVQSGSewrslPYLSSDVGVHAY--YADLVMISRPePAGDtaGPPGLAES----LVLSSARPILLIPPH ->tr|L0IFC6|L0IFC6_HALRX Universal stress family protein OS=Halovivax ruber (strain DSM 18193 / JCM 13892 / XH-70) GN=Halru_2976 PE=4 SV=1 ----MTFVVPFDGSDLAEAALVRAVEYGAALDVAVTAVTVVPERTRYarekswigrdenydpgrvveSLRGRVETLAPEASFDfeRIREFPPEAEIAEHIGALALEHDPAVVFLGSDNVGRVVTP-LASVGVHVAAEDDYDVFIVRR- ->tr|W0K441|W0K441_9EURY Universal stress protein OS=Halobacterium sp. DL1 GN=HALDL1_10225 PE=4 SV=1 ----MTLVVPFDGSELAAAALVRAAEFSAVLEEPVLAVSVVPEgGASFarerdlidadeqfemetvvaRLREAVRSLCPDAEFRhlVVDRYARAGTVAKRVRRVAREAEASMVFIGSENAGRMVTT-VSCVGASVAADDAYDVVIVRH- ->tr|A0A1H3ATT7|A0A1H3ATT7_HALVA Universal stress protein family protein OS=Haloarcula vallismortis GN=SAMN05443574_1314 PE=4 SV=1 ----MTLVVPFDGSELAEAALVRATEFSTVFEEDVLAVSVIRKgNVKYarehdwigpneefdletvvtALHKQVMALCPSSDFRhtVLDRYAPAGAVAKAIRKMAKREDASMVFIGSENAGHLVTS-ISSVGGSIASDDAYDVVIVRH- ->tr|F4L4B8|F4L4B8_HALH1 UspA domain-containing protein OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_3939 PE=4 SV=1 ---MDSILCLTDFHHNSAQPFRYGLHLTRHLHNELYVAHVEDSADFPtvedsvnldeniateqlDALQKLRQFIQTNTPEedqklPVRGVIVGDNLWDGIEVLTGKYDADLIIMGMRNRMGLAGRIFGGLASKMINLAEVPVLMTPPG ->tr|A0A133USI7|A0A133USI7_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA259J03 GN=AKJ39_03705 PE=4 SV=1 ----ERVLIPYFGENLPKRAETRALEKLEK-GGELFLLHILDEAPTRslryrtgqfgdgsemvktfrktmknvqekkagKYIDEVKSRAGKKGIS-VKPLFTSGSPGEETVKAVEKHSIQLVIVEDL-RDTVTEIFAGDEIDYISNKAPCKVETVSS- ->tr|A0A0Q3HU24|A0A0Q3HU24_9FLAO Uncharacterized protein OS=Chryseobacterium aquaticum GN=AR438_10465 PE=3 SV=1 -YEFKKILFPVRVLDHLNDKLELTLSLAKKNKSIINILGISDQNDVTsltTAYLDVKKKLFIKSADYTSDFLLTEDKAVHISKFSKEENADLIVLNYEDEESWKSFFSENFLKKIINNTEIPLFFLKP- ->tr|A0A0Q4DRS3|A0A0Q4DRS3_9FLAO Uncharacterized protein OS=Chryseobacterium sp. Leaf201 GN=ASE55_13655 PE=3 SV=1 -HTFENILVPVRILDNLTEKLDLSMAIAKKNRGVISLLGICAEHDIPeikSAYLELQKTLAENTRQYHAEFMITRDKAIRISEFSRDDQADLIILNDKDEDSWKSFFSENFFKQMVNNTDVPLFFFRN- ->tr|I2EZ46|I2EZ46_EMTOG UspA domain-containing protein OS=Emticicia oligotrophica (strain DSM 17448 / GPTSA100-15) GN=Emtol_3823 PE=3 SV=1 -SSFQQVLFPIGNTSANVDfdNYWALKNMIPSDDLEIDLLGISRFEDYEtsdRVKEKVSELsnfIKKDGLKASFQNIFCDNITRFILEYASINQSDLIVINPNIDSDWEKFVLGNNMRKIINQAQCPILLIKP- ->tr|A0A1Q3X269|A0A1Q3X269_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 46-16 GN=BGO69_14430 PE=4 SV=1 -LDFRNILFPVRPVLNALSKYKMVFPIIKKNNARVLLMGAINEQESEkvkTIKQMVDSTavqMKSQNIHVDRKLYFGKGIAREIIATSNRKNTDLLVITAALRRGLKQFFVPGFVQKMINESVIPVLCVKP- ->tr|A0A151G8R8|A0A151G8R8_LACPN Nucleotide-binding protein OS=Lactobacillus plantarum GN=AYO51_07960 PE=4 SV=1 ------ILVAIDNHISAFKITQYAIELANALDKSLYFVHILDDSLPkykrnprnpwersnldalsEFYLKDCANMALDTNVNHVFHSLIYGRTKNTLVRLSNMKNVALTIVGASGYDNLYNNRIGHIAQYVSCWSKGTVIIVR-- ->tr|K7YYK8|K7YYK8_BDEBC Universal stress protein OS=Bdellovibrio bacteriovorus str. Tiberius GN=Bdt_3123 PE=3 SV=1 -MINHSLLIADELEHkdeaslkRSQVNRRFASDLSVRLNCPVSLLYVKTLKDIPGrlalsyaekakvishKHHQLAPVMNNFAV-PGKLIVKFGSPVKEISAAVKDNSVEALIVGSRALKGMDRFFLGSVAEEVVRNVKRPVYILGPG ->tr|A0A1G6C471|A0A1G6C471_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Flavobacteriaceae bacterium MAR_2010_188 GN=SAMN03097699_0454 PE=4 SV=1 -NKIKKILIPISFSEGSANSLRQSFSLF--ENTELILLHCYPPYAYNReydfgqisydkgiegmLVEFYRKHRAKKIAQNIKLIAREGSVSETIAEISG--DYDLVVMSKRKLQETGGYWFSDRVIFIAFYSHCPVLLLP-- ->tr|A0A024IYW4|A0A024IYW4_RHIRD Universal stress family protein OS=Rhizobium radiobacter GN=BN949_03751 PE=3 SV=1 -KTPKDIVVYIDTADVSVCRvyIDYAVSLASAWDAHVVVAFVPEDLIATpshgfargqainsmitsfegrrhdaeeQLRGLLSDVASATGVN-CELRICSGETGEALMLHAR--HAALAIVGTGRDPDR-AETALTVSEDIIFASGRPSILLPTF ->tr|I0ANE9|I0ANE9_IGNAJ Kef-type K+ transport system, membrane component OS=Ignavibacterium album (strain DSM 19864 / JCM 16511 / NBRC 101810 / Mat9-16 -SKINRVLVPVRLRSDFDVtniktiETKLLEKINSKKPLMVTLLTVVSENEKMIAQNFLNNLQSKLETLKVDKRIIVSeKPLESILNNLKT-GYDLLVVGATEKVNTNDSVINPFIDHLIKLAPCYSLIISSS ->tr|A0A1Q4SG75|A0A1Q4SG75_9CYAN Sodium:proton antiporter OS=Scytonema sp. HK-05 GN=NIES2130_06145 PE=4 SV=1 -KRIRRVLMPSQGGPNITLAAQLVSHLAHQNSLEVTVLFAESdkkprrksvstvatAVKETTAEAAVATVAEKIqlptdAPVPVQTKIESGtNKAEVILKEACK-GYDLIVLGATERQRSRGALFNLLVDRVVQEAPCATMVVKSN ->tr|A0A0D6NH87|A0A0D6NH87_9PROT Universal stress protein UspA OS=Acetobacter orientalis 21F-2 GN=Abor_001_083 PE=4 SV=1 ----SSILVVWDNSVCAHKMLQASRTVLARASLLHLLAPHGQELPYSLLPPVMMEEH------RLGQPFSLPRVMHTVATAKLAYPADLVVLGFDldctHNTQSGGGIANSSAGAALQAARVPLLV---- ->tr|A0A1F3KAA9|A0A1F3KAA9_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_43_11 GN=A2X09_13325 PE=4 SV=1 -NHFDKVMLPLNVFRRWRNKLETAIRICRLFKCTLFITetnpGVVHPEEYRNRIEEIARILTEADIDfILVPGQPDGDYDKVILNKAISARIKMIVLMSDEEEGGNHFKPGPWDEKLIfNEEQIPVLCLNP- ->tr|A0A1F3KPS6|A0A1F3KPS6_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_43_11 GN=A2X09_16540 PE=4 SV=1 -NeGYQRIVFPISNDMEVRQMVRLAISLQKRFGATLLLIqdyedEPRFKAQLEIKTQQILEELRRYDVQyRL--sRSEEGDFAANVISFAAVENADLILVMSLADGETPGFFFNTWSEKIMfNTAQVPVLCLNP- ->tr|A0A1V6JFT3|A0A1V6JFT3_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin012 GN=BWX51_00447 PE=4 SV=1 -NKFSPMLFPVNLFRGWAKKAKALTHLSQWFGKQVIVVenhsSVMFASEIERERYRFSEKLNSFGLEcTFASYLLQGSYTNQLAYYAKRYKAGLLVLMNDEEEESLHFRPGLSETKIIrSKIGLPVLCVSP- ->tr|A0A1G0VA43|A0A1G0VA43_9BACT Uncharacterized protein (Fragment) OS=Ignavibacteria bacterium RIFOXYB2_FULL_36_7 GN=A2330_07370 PE=4 SV=1 -HSFKKLGLAITSSPTGIALLKEAKRLKDIFNAELFLIHVEEKTPEAEKSLKSIIDNSGLSFQDTQLIWASGDPANTILNTSKNAGVDLLVAGALEKEGFIKYYIGSVARKIMRESSSSLLILK-- ->tr|A0A1X6XNV0|A0A1X6XNV0_9MICO Osmosensitive K+ channel histidine kinase KdpD OS=Brachybacterium faecium GN=FM106_19630 PE=4 SV=1 ----VKLLTYLDEEHiqGTEKCLRWTARLAAAFRSEWTLLVIENEEDEHDehddlmreQRFKVMKLAQSLGAD--IVTLSGHDTLDTLTHYAKMTGITDIIIAKQRNHSHVHRLFKqELEDDLIQrLPQVDLHIIPYH ->tr|A0A0Q8N302|A0A0Q8N302_9CAUL Uncharacterized protein OS=Phenylobacterium sp. Root700 GN=ASE02_11480 PE=4 SV=1 -------MVVVGGEPASMRRVHQVIDLAGRLGAGVTGAFLRPMFPLSdygaggawmsqgllqeaveahalvvdrteARAQRAFLAAAELQHLAADWIVLDTV--QQLVERAR--LSDLVVVPPGPLPEGGEVTI--SAGQLGLACGGPLLVIPDH ->tr|A0A0Q6NJ39|A0A0Q6NJ39_9RHIZ Uncharacterized protein OS=Mesorhizobium sp. Root102 GN=ASD12_05920 PE=4 SV=1 -MGYKDILVFLDGSVGNVARVDFALSLAKAHGARLTGVDVDSAAAFAGEWSERAKSLEEtfhasanrFGV-DVRFKVADRTSQEWKNYYTP--YADLVIATQPHREVAD-MILPEVPGDLLTSAGVPMILLPRD ->tr|A0A239SJ76|A0A239SJ76_9BURK Universal stress protein family OS=Pandoraea sputorum GN=SAMEA4530655_02403 PE=4 SV=1 -MSLRKICVHVDDTATGAARLRFSAELARQHEARLSGIYLPHRpgavhsgqlqssgehFQTEAHSRTALQAAEHlfsklcaeADI-VGDWRTPYGAAPTLLANAAR--ATDLCIVGQPDAPGGVAALGLDGLGDVIRWAGVPVMGVPHN ->tr|A0A239HGP7|A0A239HGP7_9BACT Nucleotide-binding universal stress protein, UspA family OS=Granulicella rosea GN=SAMN05421770_102394 PE=4 SV=1 ---VQEILLFSDFTPESTSAAPYALMLGQEFGLPVDVCQLLPvvvEDNPRLRRQLAEDYCQSmkhvladenAVWCQPAFQLERGMQLEQIVDRAKSHHAGLIVLGAHTESLVGRHLHTSFAYQVLGRATCPVFTIPRL ->tr|W0A6M1|W0A6M1_9SPHN Uncharacterized protein OS=Sphingomonas sanxanigenens DSM 19645 = NX02 GN=NX02_09315 PE=4 SV=1 --MVKSILLHIHDDCGQAERLAVALDLARAHQSHITCVQVTPFNSYvvgdpfgglyasselldalqardDEERERIEQRLKSEDI-SWDWEHADGNAADALVSCGR--LADVLILSRQNKGQDDTPEPLPIVADVAIHARAPVLVVPPG ->tr|W1KL11|W1KL11_9SPHN Uncharacterized protein OS=Sphingobium chinhatense IP26 GN=M527_02575 PE=3 SV=1 --AIRDLLAVVDTSDCDEQFVQDALSFAELHQARLTLLVLSviPSPEYgnmygppfivlrdflgavEAKQQRIAGWASRAGI-EIRTVSDlPEGIYTSASVHAR--YADLVLFGPQDA-YGYPLIRRQIIESVLFESGRPVLVLPRE ->tr|A0A1M2ZMU4|A0A1M2ZMU4_9SPHN Uncharacterized protein OS=Sphingomonas sp. 66-10 GN=BGN95_11390 PE=3 SV=1 ---MKNILLLVHDDDGQEARLSAALAVRTALDGHLVCLDVIVTSDGfyrmgggpigmlvleerqkeeRHNKAAVHARLVADNI-PFSWNDSVGELDTILIDAAG--LADLVVLNSYLSDDIADPDMAAKIRAILRRVSTPILAVPRH ->tr|F2IEF2|F2IEF2_FLUTR UspA domain-containing protein OS=Fluviicola taffensis (strain DSM 16823 / NCIMB 13979 / RW262) GN=Fluta_1482 PE=3 SV=1 -HKIKTIVMTVDLSRESVQVVKYASRVAKTFNSKMYLVGQKYSDEGlmqkiEVNLKVANGYLKDHGLEANIHLLENTNFEKNLIGYCKEIKADLLAATCYQ-DGFSLFS-TNLVQSLSENELsIPVMTLDG- ->tr|A0A1V6BKZ1|A0A1V6BKZ1_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin141 GN=BWX95_00446 PE=3 SV=1 -RPVKKMIIPVDFTREVKQVLSVVIRYAHLFNAEVILFEQLNRDSFiqhriTNNLNYFTSVLNDEKIVFKIVKKEfSlDDKCEVVTKEAAETNADIIVTTIDPDKGITDYIMGVEEQKLLANELqLPVLCVNI- ->tr|A0A1Z9FZC6|A0A1Z9FZC6_9FLAO Uncharacterized protein OS=Crocinitomicaceae bacterium TMED135 GN=CBC95_03110 PE=3 SV=1 -NGYDNIVVPLDLNFETKQKLELVAKISHYFDSQVHLITKDEDDDFiknklKANQLWAVNYLKEKNVKHSSHLVEkGATLTEGIFKLSKEVDADLIAIMNLQDDTLLGILENSFQEEIVANDLkVPVLSVHP- ->tr|A0A1S2DGL6|A0A1S2DGL6_9GAMM Uncharacterized protein OS=Salinicola sp. MIT1003 GN=BC443_05995 PE=4 SV=1 --MQNSILIPMGKKSASMAALRKARGIAQHDHTRLYLLHVVEPRETgdvlgaatgaathaldkedvaraEAFLEERWNRLNEPMA-AVNFLIKDGKLSETIAEEARRLKVDTIIMGTSKSSPKWEGMIG----KIRKSTPCKLTIVDEE ->tr|A0A1J5DYA1|A0A1J5DYA1_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_63_29 GN=AUK47_07050 PE=4 SV=1 ----NQILVAFDDSRYSGRALAYAIAVANSGGAKIALAHAIPPLARYfkevlfpyaamgvdeveieaELLDNAKARLGEAALklvgadskVEFETHVTTGaSPATGLVQLVDQLDASIVFCGAFGDTSPILGRIGATAQGIIANAHKPIFVVRD- ->tr|D1Z015|D1Z015_METPS Putative universal stress protein OS=Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE) GN=MCP_1965 P -NLYNKILIPITRTSNMKFLVNFVDHFLK-PGGEITFLHIIASDLFAispaewrramSTISTTHLLTATEGMRVDYRVKNSLSVASGILEEADAGDYDLILLATSTYRKRLKHIFGSNLDEIVKKARVETIVFR-- ->tr|D1YW66|D1YW66_METPS Putative universal stress protein OS=Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 / SANAE) GN=MCP_0616 P -ILHDSVVVPISRPETIESIVNIACDMLA-DDGTLRLLYVIEVPyQLPlefaetrktkatELLAMAADHSRKRGFTPRQEVVVARDIPQAILDMADRYKADLILMGSSQRSVPEKVLFGSIVGRVLREAPCEVIVYS-- ->tr|K1KKU6|K1KKU6_9BURK Uncharacterized protein OS=Sutterella wadsworthensis 2_1_59BFAA GN=HMPREF9465_00072 PE=4 SV=1 ----TGFVLV-VERPDVQEVIREASRLARNFSGDWHVLWLGKPGESrehRCRVAETLAFAESLGAV--TAMTSGSFA-AEVSAYVREHNLSMIAIADMG-llaTM-----RRrHLLRHVAP-K-ITFVILSSN ->tr|A0A1R0ISP4|A0A1R0ISP4_SULTH Uncharacterized protein OS=Sulfobacillus thermosulfidooxidans GN=BFX06_14765 PE=3 SV=1 ---MQRVMVAVNGSQASLEAVKAACTLIN-PEGEIIAVDVEDIAQFYqdyalnayggalvlephdydqewekearqvhsRVEAIAQQYQVKLRWEVLRLEPGQGSVAEMINQAALKHHVRAIFVGRHRGAQFMEGLLGSVPRWLVTHSSLPVVVVPP- ->tr|M0CM35|M0CM35_9EURY Uncharacterized protein OS=Halosimplex carlsbadense 2-9-1 GN=C475_13717 PE=4 SV=1 -ETIDSILLPVGTGPHAALAAEAARAVARHADASVTVLHVVSPDAAAEETADGEDLLTFADHVlgpdvRSETELKAAaDTTDEIVRRAK--EYDFVSIGAPEQkSGLKEIVFGSVQQTLSELNGVTVLMSRDS ->tr|L0JMZ6|L0JMZ6_NATP1 Universal stress protein UspA-like protein OS=Natrinema pellirubrum (strain DSM 15624 / CIP 106293 / JCM 10476 / NCIMB 786 / 15 -NQPTDILLAVGTGPHSVLGAETARAVAKASGASVHALHLITSSDDGPARQKGRKALSLAEYVlsdlpNVECETREVeTATDELLTEID--NYDLSLIGTPTKsSLLSRLFAQPTSEKVITQSTTSVITVRQP ->tr|A0A0S7BM31|A0A0S7BM31_9CHLR Universal stress protein family OS=Flexilinea flocculi GN=ATC1_131391 PE=4 SV=1 ---IHRMMIAVADLEADKEYLRSAIQFSKKYGAWVGIVHVVKRQTMlhsewmKKYQAEIEDMLETEGV-QGKFFPLYGNLTKILSERAF--WSDLSLFKLKYRPQLKKiTLTEDGWNAIIMRIPGPICVIPE- ->tr|A0A1V5Q4C4|A0A1V5Q4C4_9CHLR Stress response protein NhaX OS=Chloroflexi bacterium ADurb.Bin344 GN=nhaX PE=3 SV=1 ---IQRMMISVRDPIEDFDYLQSAVCFCKQFNAWAGIVHVVKRPSMldsewiRKYEQDIQTLLEKENV-KGKFFVLKGNLLKNLSDRAF--WSDISLFKMNYRPSPSRyRSLGSGWNSIFMRVPGPIFVTPD- ->tr|A0A150WP32|A0A150WP32_BDEBC Uncharacterized protein OS=Bdellovibrio bacteriovorus GN=AZI86_02415 PE=4 SV=1 -----RVVLAVDTEAPpTKKALRRFARLVRPLGTPVDILHVQRKANFvasligastgpkesEAILASTLEDLRSLNLDgKIHTIEEEDSVAATIAKFANNQGAWITATSSPTRDIRHRLVWGSTTQNLLEELSCPLLVLRSS ->tr|M1P219|M1P219_DESSD Kef-type K+ transport system, membrane component OS=Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1) GN=UWK_00939 PE=4 SV= ----EKILVPVTDMDDLAEVYPVVAALDTVGEHQIQLLYLISSDTDQDDINAHTERVyhwlkEQPKRVHLSVKAVPTDSRvECIQQEAE--KHDIVVMGAIRAQGVRKFFFGSLADSLAKKLKKPFIVVYD- ->tr|A0A1M7Y761|A0A1M7Y761_9DELT Kef-type K+ transport system, membrane component KefB OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_02318 PE=4 SV=1 ----ENILVVFTEIDELAAMYEIIAALDSIGEHKLRLMYLVPSDAEEKEIRFLEKEVanwleKQSNGLRATILVSPVDSRlDAIEDAAE--DADVVVMTAGEASGVERILFGSLVDSVAVKVRKTLIVVYN- ->tr|A0A1W9M9W4|A0A1W9M9W4_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium A2 GN=BWK76_10440 PE=4 SV=1 ----DRVLVPYVHAEELEIVLPLLEALATVVHPRLTFLHLMSSDSSEEELEQARDEQarwlyARFLDARVRQRIEASDCRtESIRRELY--RHDLIVMAGQRQPGLARFLFGSLGLATARSCRCNLLLVIA- ->tr|A0A170PE19|A0A170PE19_9CHLR Pyruvate-flavodoxin oxidoreductase OS=Ardenticatena sp. Cfx-K GN=CFX0092_a0442 PE=3 SV=2 ----GPIIALYDGSATGLRALRLAAELAE-QGGDLRVLLWASDEEEAFERREFAAQLLEESGVEAQIQHLSGDLPLRVLQWVNRQKGNLLLLGGGD-----NHLPPDIFSLLLDEAEQHILVI--- ->tr|K9H3F2|K9H3F2_9PROT Uncharacterized protein OS=Caenispirillum salinarum AK4 GN=C882_3146 PE=4 SV=1 ----APLLVPFDGSDAARRALDAACTLAE-DGPAERVAVLAFGDADALA--AAARDICAAHGTVPRVQALP---PLTLARLVRIadFPEALLVLPAQL-----PMTLGLSTPDLIDRLGCSVLLV--- ->tr|C8X118|C8X118_DESRD UspA domain protein OS=Desulfohalobium retbaense (strain ATCC 49708 / DSM 5692 / JCM 16813 / HR100) GN=Dret_0824 PE=3 SV=1 ----DPVLVIYTGSPLSKQALHMARWLMHDQKRRLKVLVPAEQNATMEPRRQEIHGLMADVTDRIQLQSFPVRSIEAFVHLLQEEGRGPLVLPCDE-----Y-WLGPQLEGLVSRLPNPILLV--- ->tr|B3EN43|B3EN43_CHLPB Uncharacterized protein OS=Chlorobium phaeobacteroides (strain BS1) GN=Cphamn1_2124 PE=4 SV=1 ----GPILVLYDGSRGSKRALETACSIAS-AKNTLHIFLIANTESAASRLREETASIIGDRKKKTELHVLPWTDSAMLAQCIHMTGPGLVVLSDSS-----EAISPESVYRLIDATNYPVLLV--- ->tr|E1YLQ4|E1YLQ4_9DELT Putative uncharacterized protein OS=uncultured Desulfobacterium sp. GN=N47_E45490 PE=4 SV=1 ----KPVAAVYNGTGSGQKTLDTSVYLAQSYDAPLTVILLGDSDADIEHKQRRAEEMLQYSGIRVDFRHLIKPIMAELSVYIRQVEMGPVVLPNME-----DLFEGEELCGLVEEIDNPVLLI--- ->tr|A0A0S8BWL9|A0A0S8BWL9_9DELT Uncharacterized protein OS=Myxococcales bacterium SG8_38 GN=AMJ62_07475 PE=4 SV=1 ----RPVAVLLDQADSGSRALEAGIELAEASSRPLLVFLADPSPRAWNEVRRRLQSF----GPKRaAIHRVREAEREVLAAAIRRASPTVLIVAAGE-----GGFEELRLTSLRQELRCPVVVV--- ->tr|A0A0C1RJ58|A0A0C1RJ58_9BACT Universal stress protein UspA OS=Methylacidiphilum kamchatkense Kam1 GN=A946_09470 PE=4 SV=1 ----PPFGVLINPSKDFLPILTFAANLAKKFNGGLTLFVFNGTLSSAQK--NYVE-ALASDMAQLsVIEG-LGKDPMALASTIAEEKIGLLIFSMSG-----IDLKKATLKDLLRKLNCLVLLS--- ->tr|T1B519|T1B519_9ZZZZ Universal stress protein OS=mine drainage metagenome GN=B1B_06500 PE=4 SV=1 --MYRQLLIPVKEASEVEPTIDIGARLLE-PNGEIRILHIIPTTRMPQVTREWRASVNivvpahetgAALDVRVEPEVRANvDVPGEILESAEAHEVDAILMTLAGDRRSRNPFVGHTASAVLHHARCDVVIVN-- ->tr|Q1NSH8|Q1NSH8_9DELT UspA OS=delta proteobacterium MLMS-1 GN=MldDRAFT_5054 PE=4 SV=1 --MLQNFLFPVHPGKSPTQKLLAMAQFAGLFKAEkIYLLLVTSPNNSkqIKWLKELEQELLELGL-PVERLHRHGHIPSQITAAART-TTSIICFFKKWKNPLQKALAGSIVSDVIRMSDEPVLIYK-- ->tr|C8X5G2|C8X5G2_DESRD UspA domain protein OS=Desulfohalobium retbaense (strain ATCC 49708 / DSM 5692 / JCM 16813 / HR100) GN=Dret_2377 PE=3 SV=1 --MLRNFLFPVYA-KSPVNTVLAQAEFIRSFEPEkVYLLYVASGNSSrpIKRIDRIEKGMRELGL-PVERLVRYGHVPSQVVTTAEA-TQSIICFTKKWKNPIKKAVAGSVISDVVRMSDEPIMIYK-- ->tr|A0A1F8NIQ9|A0A1F8NIQ9_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_13_66_10 GN=A2Z66_05255 PE=4 SV=1 -----RLLICIDPRVPDRATFEYGHRLAQAAAGPATLLGVVSDRARDAEARSVLEPLMNEanrVTPNFQMRVRVGIASSEILLEAQEAHDELIILGVRRARR-GHAAPGSTARAVLEQSEAPVLLVQKP ->tr|H6SLE9|H6SLE9_RHOPH UspA OS=Pararhodospirillum photometricum DSM 122 GN=RSPPHO_02188 PE=3 SV=1 -TLTMKVVVHVDAGESWPRRAEAALRFvSLRGGGRILGVYGqmatvlpayayhGDKAAIGdEAAPQRQKFFEMLsgieGISPDWHTIHSANPDFIASELTAnAQYADLTILGQNDPR-TADRVPADLAEQVVLNCGRPVLLIP-- ->tr|A0A0S8IBX2|A0A0S8IBX2_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SM23_ 63 GN=AMJ88_01975 PE=4 SV=1 ----GYSLIGIGREPRDPNHMRYAEAISRAMGLCPVLFHVSPPDESLEEGERLLANARSMlSSKDVEVLHVEGNVENGIVNELKRRPYQLLVMETSFSDP--DQPASQLSKRLANRAKVSVLLVRNP ->tr|A0A1F8Q2L0|A0A1F8Q2L0_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_54_11 GN=A2136_10760 PE=4 SV=1 ----MRILILVTKMPEDGPLVSFGGLVAKLTQSSLTLLHVAPSKAKQERTDQVLNQAADLlAGLEVERRLCWGKPATMAILEMRQGNYDLIVIGARQASTAMEQSLSLASRAILQRAPCSVLVVRGG ->tr|A0A1M7QDL1|A0A1M7QDL1_9BACT Uncharacterized protein OS=Chitinophaga sp. CF418 GN=SAMN05216311_108110 PE=4 SV=1 -VPIRKSILLYDGQPSSVYAIKMFSYLLPVLNAlPSEVITVKNSDDDLHLPDnRLMKEFMKRHQPDAAYTVLKGDAEEEILLRLRSEdATAVIVAGAYKRGVVSRFFRHSMVDVLMRELRWPLFIAHQ- ->tr|W9RI82|W9RI82_9ROSA Putative urea active transporter 1 OS=Morus notabilis GN=L484_025992 PE=3 SV=1 -LRLHSIILSMPEA------------------ERIYLQQ---------kdkaKKKDIFDHQDNqavpSNSSSRTRSVL-------------------------------------------------------- ->tr|A0A1Y2BAZ9|A0A1Y2BAZ9_9TREE Na+/solute symporter OS=Naematelia encephala GN=BCR39DRAFT_557944 PE=3 SV=1 -LSTYVGFSHQPTYMST--------VPFLmGVDAS---DVVVIWEYALQnllgtgsnhsk------------------------------------------------------------------------------ ->tr|A0A1Y1HVH9|A0A1Y1HVH9_KLEFL Urea transporter OS=Klebsormidium flaccidum GN=KFL_001180190 PE=3 SV=1 -AKIDAILRSNPEY------------------EKAYTHV---------kakeMSPPPKD----------------------------------------------------------------------- ->tr|A0A139DDT4|A0A139DDT4_9ALTE UspA domain-containing protein OS=Marinobacter sp. T13-3 GN=AWU57_4082 PE=4 SV=1 -------LIAIDPEDDheGKRALDAGLDLLDE-DGELHLASVYSPGGGgffphvaeeapeekEAEVHKKLDLLVRKYLPmnrEATIHVVAGNIGEKLVALAGQLSSDLVVLVSRGSNKRWS-LRKATVEYVAVNAPCRVIVLPA- ->tr|W4GLI4|W4GLI4_9STRA Uncharacterized protein OS=Aphanomyces astaci GN=H257_06567 PE=4 SV=1 --PTTSFCICVDGSRVARVACDVGVSLR--RQGMVHVCCIDEFSTESRyspefITKDITALCRQQGVPDGKFVVRAqaqrltqSTISSQLLELRDSCRADFIVVGAVGTKGPQPSQLGSNTMRAIRGSPVPVIIVPP- ->tr|A0A1V9YYM6|A0A1V9YYM6_9STRA Uncharacterized protein OS=Thraustotheca clavata GN=THRCLA_09149 PE=4 SV=1 --ATPSFGIFVDGSRNARLACDVALSLR--RSGEVHICFIDEFAANASysldfVVDDFTQYCRQNQVPKSKMSVKSqavrmtQSMTTQLVELSDNLNVNFAVLGTFGGKGPQPTQIGNTAMGVVLQSSTSVILVPP- ->tr|A0A0T5ZN84|A0A0T5ZN84_9BACT Universal stress protein UspA-like protein (Fragment) OS=Candidatus Dadabacteria bacterium CSP1-2 GN=XU11_C0057G0001 PE=4 SV=1 -RRYQTIVIAMALDERDVTTLRHAAYFAQAAGSQtVYMAHVTPTFDLPPEAAvqspdvvlpidediehrlrqiYTEQQIEFPPGTRIECAVRQGSMVPEIVRLAAQKSADLVCLSRRPHEDHDP--LSDSAVKVLRIAPCSSFLIPAS ->tr|A0A150G4J9|A0A150G4J9_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_67g295 PE=4 SV=1 -LQYNRVLLTIldanpFLSDGSRTAVATAALMARQYKSKVTVLVVDEPGtenqDPTRRLESITWHLRERGCENFELVEKAITspASVLVGDFADEIAADMVVLSSEAVHAKHVD-----ANQLAEFVSCPVLLLP-- ->tr|A0A0C1XIB5|A0A0C1XIB5_9CYAN Uncharacterized protein OS=Hassallia byssoidea VB512170 GN=PI95_37035 PE=3 SV=1 -RGFQKIAFAFDYWRTLSLPTEPLAWLLQTFQSELTVLQVMEESISaeaEAELRQLQHTFSTAANRNITFHtVHAGRVPEALNNYVLHNEPDLLALCATHDSLLRRMFHRSTIRHLSSVTKCPLYIFPFE ->tr|A0A1F3Q664|A0A1F3Q664_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_35_15 GN=A3F72_14365 PE=3 SV=1 -GTISKIVFAWSYETNYPVLISMLNELITIFNPKIiftpliTFLHVSK-HPSplsNETFLLLKKEIGSEikEKIKIEFEeIVSDDIPESINNYMEKSKSDILMMTVMDRGLIGNIFHHSVSRKITGIAEYPFLVMHV- ->tr|A0A076HW10|A0A076HW10_9BACT Uncharacterized protein OS=Hymenobacter sp. APR13 GN=N008_18315 PE=4 SV=1 -----RLVFSADFSTLPLHTLPRLSALAEAFPGTLDLVQFYAPTERSRRlaLKQAQTRALRQLTwPHVHTHLLeDESALEGVSEFCARQQAQLLIVAPASRAELLHYFDACYTTTQAYHTRIPVLVVRSA ->tr|A0A0H4VMH5|A0A0H4VMH5_9BACT Uncharacterized protein OS=Rufibacter sp. DG31D GN=TH63_03855 PE=4 SV=1 -----KIVYSLNFHDIDTSVIQRVQALARPFGASIVLLYLHGKIETVELcqLQKKAARLKEQFPyAEMSAVFQeEEDLLEGLNDFAEGHSPDLFVMATRDTHLVHEYFSGHYRKTRAYHLNTPFLNLYQA ->tr|A0A127B3C3|A0A127B3C3_9BACT Uncharacterized protein OS=Rufibacter sp. DG15C GN=TH61_12065 PE=4 SV=1 -----EIVFSLDVTDTNEAVMKRVQKLAQKFNVHLTLLHLHSQLDGVSFcqVKKAAATLKTELPyPNLDIVCQeEDDLLEGLNSFSGRATPDLFVLATRDTHLLQEYFSSDYRKTSPGHLRTPLLNLYQA ->tr|A0A1G1T7A2|A0A1G1T7A2_9BACT Uncharacterized protein OS=Hymenobacter sp. CCM 8643 GN=BEN47_12300 PE=4 SV=1 -----RLVFSADFDALNLHLLPRLSGLANAFPGPLDLVQFYPRTARPRRrqLKQALGRAAAQLTwPTITEHLVeDEAPLEGVSEYCARTLAQLLIIAPANTAQLLRYFDLCYTQTQAYHTQIPVLVLQAT ->tr|A0A1M6QC97|A0A1M6QC97_9FIRM Nucleotide-binding universal stress protein, UspA family OS=Desulfotomaculum aeronauticum DSM 10349 GN=SAMN02745123_00964 PE=4 SV=1 -----RILVPFNGTDSSWKAINYALDMAKRNNLIRITVIAVDSRDYRfmsvnpnnnpfsiiddfynyliNQTKKIKDLFLKESV-PLNVMIEKGDVAKSILKAVDDLYIDHIIMGRGKLSTL-EVILGSIIYKVIADIKIPVTLLR-- ->tr|A0A1F9FUF8|A0A1F9FUF8_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_44_16 GN=A3C46_05570 PE=4 SV=1 ---VKTILMPIHLSPSFQKVAERGITFLKAFGEkyHVLLLHAYLVPHVDqkeliqkndevkrqsheglEALKKTLKNIVSNGNMTFETRSHLGTWENVISNVAATEKVALVLLPFGDDD------FMRRISHMLERISCPLLLLPSS ->tr|A0A1I0SZY4|A0A1I0SZY4_9NOCA Nucleotide-binding universal stress protein, UspA family OS=Rhodococcus kroppenstedtii GN=SAMN05444374_103185 PE=3 SV=1 --SPVNIAVLHAPTPEGDAALTAASQRARETSAPLTVLIVHHESPATEVAAAAVRESVADSVRatvgDTETRYrelgpsNGADAIATLIDHIDDANYDLIVLGTKRRSTVGKLLLGRDIQRIVLEVTAPILLVKP- ->tr|A0A0B6KI38|A0A0B6KI38_FRANO Universal stress family protein OS=Francisella novicida GN=CH70_191 PE=4 SV=1 ----PYVLVCCGYDEATPSLLRKGKLLATTLNARLIAVFVQKPNkvatkLNFGVIRRYKMLASSLGYN--IDHILGDRLSDSILEYAKSIGATDLVIGKSIRPKWKDKLfGSVVYDIIRNNNNgMQVHIVSIN ->tr|A0A1W7A1I5|A0A1W7A1I5_9STAP Sensor protein KdpD OS=Macrococcus caseolyticus GN=kdpD PE=4 SV=1 ----QIIAVGMTSSPTSHEVIRAGARMAKAFKAELVGIVVENEDsIDSVVLNENLKLLDALGGR--YVKLYGDEV-EQIGDWCRLNRVDKLVLGRSLKQKWF--Q-DDIITKINKNYQeINVIIISNA ->tr|A0A1F3T9F3|A0A1F3T9F3_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYA1_FULL_36_14 GN=A2202_08540 PE=4 SV=1 ----FRILVPILPSSDGEYLIRMTRRISSGLNAQWIAAQIDGQRknneNEDRHQKKNALLAKQLGAE--VTSIHDTSFLQGMRRLVKEYQITHLVISKKQKMLLk-------QLSALSKSFPdVDIILLSSD ->tr|A0A1T5AN72|A0A1T5AN72_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Pedobacter luteus GN=SAMN05661099_0888 PE=3 SV=1 -RAIKNVLIPVNFSASATHAIETGIGMCMRHGATLHLLQVNRDSVMphpagrnallmdlrlqarkndQDALEWKAKSIAQDYRISCFFHLREGQFAKTVASVAKDFYCDMILLERQIPSSFAGLINTHSAYQILFQTDCPVMVIPA- ->tr|A0A0E9LZQ8|A0A0E9LZQ8_9BACT UspA protein OS=Geofilum rubicundum JCM 15548 GN=JCM15548_13104 PE=3 SV=1 -SEIHKIVVPLDVNEKDQSGLEKIADFAQALQARVNLLYVDMDGetPPDLAIEKMRDLAKEYHLANYAISVVSSHTLeEGIQGFVRKNNPDMIAVLSQGKGKIKKLIFGSSTQDIIKEADIPVFITK-- ->tr|A0A1Q7QFN8|A0A1Q7QFN8_9ACTN Uncharacterized protein OS=Actinobacteria bacterium 13_1_40CM_2_65_8 GN=AUI42_02840 PE=4 SV=1 ---PRSILASIRGGASSRVVASTAAMLADAYGSELTLVHIQTDSQHpdrsrreWQFFEQIVEELHRPST-KVRLH-RHDNPAGGILLEAV--GHDLVIIGSRLSPSNPNILVGRSLLRMVRQLDCPVVMVRPK ->tr|A0A1M3EFP7|A0A1M3EFP7_9CELL Uncharacterized protein OS=Cellulomonas sp. 73-145 GN=BGO38_03590 PE=4 SV=1 ------------------ACVDAAAGL---GLTDVRLVHVLDEETEAgweggplglmgrgrrrpddrlgrtcnpldeagsHLLTAAAARLGGRS-GGagspgsgPEVLQLHGRTETVVLDACA--GADLLICARDGVrTERGPHSLSKVTRYVVDHAPCAVLLVWPE ->tr|A0A0D5YPT8|A0A0D5YPT8_9FLAO Universal stress protein OS=Muricauda lutaonensis GN=VC82_569 PE=3 SV=1 -TKMENILFPTDYWSKyKIKELRSLIEIAEEYMAKITVLHVKElpENDLTDKQEQNKKHLKNClkEVPYQFTEIQGKLMPDAILEHIEDHDFQLLAMMNKEHSFFERLLIKQNVDQIGFHVKIPFLIIRD- ->tr|A0A084THB5|A0A084THB5_9FLAO Uncharacterized protein OS=Mangrovimonas yunxiaonensis GN=IA57_11740 PE=3 SV=1 -KGLRDVGFATDFSITdYGDGLALLKDVATAHNAKISLVHVLkKEKELTPEQLTSQDALEAYlnPLHVTLFMLTDVPIEIGTRIFSESRQLDMMCVIAKKHSFFEKVFNKSQSKSISHHAKVPLIIFNE- ->tr|F4B079|F4B079_DOKS4 UspA domain-containing protein OS=Dokdonia sp. (strain 4H-3-7-5) GN=Krodi_2354 PE=3 SV=1 -NEPDSIGFATDFARPySHEDLQPLIELTKLWKATVRMVEVYeK-PEITQVKKDHLQQLEDLlsGVDYRFHTVPeFSSLENCINVFDDe-LNIDLLVMIDYPKTFFERLTREPVVKKMTFHTTLPFLILPS- ->tr|A0A0F9LNJ3|A0A0F9LNJ3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1559730 PE=4 SV=1 -EVPGKILFPTDYEIEfAKDCLRFLLKIAQQHSSKIEVLNVSYGNELSEAQQDNKRNLVKVlkDFNHSFHDLPEQNVIQAINNFQLNHKTNLLVMVKNKHTFVERMFFEPLIKKIGLHIRIPFMVIPE- ->tr|A0A150XUP0|A0A150XUP0_9BACT Uncharacterized protein OS=Roseivirga echinicomitans GN=AWN68_14540 PE=3 SV=1 -HKLRSLLFAADFEHIeDIDALGIIKALANMFTAEIQILHIGeGWAELNRMKTKEAAKVVEYfgQTDHSYYFIKeKLDVEDAIDQHLEHHRNELLILIARKHHFPGNLFKKRVTKKTVMRTTLPLLTIPD- ->tr|A0A0F2NT36|A0A0F2NT36_9FLAO Uncharacterized protein OS=Flavobacteriales bacterium BRH_c54 GN=VR77_12375 PE=3 SV=1 -SSPSTISIATDFKEIkKKNIFATLQPLVKDFKPEITLFNVTeEMKSIGTDEKQMAQSIANIldVADIKTSYFKHEDVIYGTKEYVKQHNTSLMVLVNKKRNFFEDLFHISFTKQISFHAEIPLLILHD- ->tr|A0A0A2MR00|A0A0A2MR00_9FLAO Uncharacterized protein OS=Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790 GN=Q766_03090 PE=3 SV=1 -TSIKKMLFLTQYEKFeM-DILQKAKEIADIFGAHIDVLQIKlHHEPIEAII---IDKWKEHfnK-ADINFHVLaTNAIEETALDYIELNHVNMVTMPVHHKKFFKRLFSFSLSTQMAFHSKVPVMSLHA- ->tr|A0A090PYY2|A0A090PYY2_9FLAO UspA protein OS=Nonlabens ulvanivorans GN=JCM19298_278 PE=4 SV=1 ---------------------------------MLHLLYIAQFDKLSQRQIEVKEFWESRfrESETKYTRHDLGDGTTVINNFINKNDIDLLVLVNSKHSFLESFLKTTTIDALGLNLKIPFLILQN- ->tr|A0A1I9XH78|A0A1I9XH78_9FLAO Universal stress protein OS=Maribacter sp. 1_2014MBL_MicDiv GN=YQ22_01440 PE=4 SV=1 -ENIQEIGFPSDLNIAyDIKVLETIKDIILLKRSALRLLYISgTNEALSQNQTKVKNFILDYfkDNVCTYHNITGKSIDESVQCFTESRNLDMVIMVAKNLNFLERILFRPTVEKISYHTKAPFLVIHE- ->tr|A0A1H1LMK6|A0A1H1LMK6_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Gramella sp. MAR_2010_102 GN=SAMN04488552_0890 PE=4 SV=1 -NPLYHIAFASELIYEfNPESLKTIKAIAEKSGARITVIHDGkETEMSQRQWKN-YNSFKSNfeGLEVSLAFSSnHIEVSKSIAEFVKHNKVEMLCMEYYKHSFVSNLFIEPVVEKIDRHLSFPFLILPA- ->tr|A0A1U7DN26|A0A1U7DN26_9FLAO Uncharacterized protein OS=Seonamhaeicola sp. S2-3 GN=BWZ22_01065 PE=3 SV=1 -SSLKKIAFTTNHINIfTIEELETLKWLVAFCKSELYILHVAdEH-HLAQKQMQNMEFFDAYfpNAFHDFIDVNYKDMFDTVHKYLTDNNINLLSMISEKHSFLERLFTRHALETFAFSIDVPFLVMER- ->tr|A0A1T0CK26|A0A1T0CK26_9GAMM Uncharacterized protein OS=Moraxella lincolnii GN=B0682_01600 PE=4 SV=1 --TPSSALLAFDNKPTCHRLLDWVVEMPLLRGMTLHVVMVAEITNSnQDALREAYVKLTQAGYKCKKQLIHSRHVASALLYYQQEHKLDMLVSGAFGQSRLRQWLQGSDTEHLLQGSDTAYLLFP-- ->tr|A0A173ME75|A0A173ME75_9BACT Universal stress protein OS=Filimonas lacunae GN=FLA_1808 PE=4 SV=1 -LYVRRIGLACDFNNVADItPAPAITALVKDFNAALHILNVGKETELASDIVRESEVLESllGEVKPQYHFIAHNDTNQALMDFVENYHIHLLLVLPRERDFADKLLHKSHTRELVLKSNVPVMALHK- ->tr|A0A1M3FZH3|A0A1M3FZH3_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 46-32 GN=BGO54_17670 PE=3 SV=1 -SKLKRIGLGIELNEVIKTiPVDFIKRLQQQFHAALYVFHISIVPgaPLAGERKEEAGWLSEilKEMDPEYHYLYQENVEEGLCRYAEKYQLDMLIVFPHRRNFFKQLFFPGHTRALALHSNIPVLFFHD- ->tr|A0A1M5CDA6|A0A1M5CDA6_9BACT Nucleotide-binding universal stress protein, UspA family OS=Flavisolibacter ginsengisoli DSM 18119 GN=SAMN02745131_02885 PE=3 S -APISNIALAYDGSGL-NGTEQKIREFVQALHARLHVIHVQVSGke---------SPGIKDllPELTPQHQTIRNEDFVSGIEKYIHSHHIDLLIVLPHKHNIIERLFYRTHTSEVLQKVTIPIMAFPE- ->tr|A0A1F2X8H9|A0A1F2X8H9_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_16_68_21 GN=A2Z12_07430 PE=4 SV=1 ----MRIVIATAGVLSPEPVARFAERLAGD-GGKVYVTTVIEVPRSFldeirseqwhpltegspgwsmeedaviaryveergeRITEPLLAALIARGLDAEVVFLEGEDPAGTIIAAADRIDADLLIMGATK-HLFDEAAWESVSTRVVREAGRPVLVVPT- ->tr|U0EKD9|U0EKD9_9VIBR Uncharacterized protein OS=Vibrio coralliilyticus OCN008 GN=N779_21135 PE=3 SV=1 --PRRPVMILMDGSPSDTLAVDYAHQFLQPQNHRLLLVTVNVVEGVEgegvretpvqemGQLKHYLQKLSERGFDvmsEAISDVLPMQVAKTIIRRGEALDAQLLVMVKHSHaSFIQRALSFSVTQEVTEQARCPVLVIP-- ->tr|E3PY31|E3PY31_CLOSD UspA OS=Clostridium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / NCIB 10654) GN=CLOST_1226 PE=4 SV=1 -MIKQKIMVCVTEQKTCERLIKKGIELTKDNDTEIFVLHVATKDIKViedpraaEELEYIFEESKKYGAS--VTVLKSNDILKTLSKFAIENDIDYMILGETRLQNEKDSVIFKLRKELGAT-KTQIEVVP-- ->tr|A0A1C6FH22|A0A1C6FH22_9FIRM Uncharacterized protein OS=uncultured Ruminococcus sp. GN=SAMEA3545435_01169 PE=4 SV=1 -NTKSAVLACVTSQYNCDRIIRIAKEIADSSDCELRVMSVLKPMSDYssvsDEIEYLYLIAKESGAD--MTVMFSDDAPKVTAEFVGDNNVERIVTGMHDGKD--NSFLVKFNELSPT---TPITMVS-- ->tr|M0N024|M0N024_HALMO Uncharacterized protein OS=Halococcus morrhuae DSM 1307 GN=C448_00857 PE=4 SV=1 ---MTLVVVPVryPLSEHSRRTLKTAIDVADEHDAALSVLHIDLYHSSKRVTQSALKNAVEEafgPLSNTRYAVRPGFLVeETILDEIALEDADIVVIGRKQTSRWRRMV---------------------- ->tr|A0A191TM91|A0A191TM91_9BACT Uncharacterized protein OS=Arachidicoccus sp. BS20 GN=A9P82_11360 PE=4 SV=1 ---MKTIIVPVDFSDESKEAAFYAAEMAKQSSQSVMLVHIMPryiqseSGRREEFLSETKRKLNQLRLrtemrgkdkIHVCTRIYSGSFFHEINKLIKSLDFFAIVVSGKYKNKTGTA-LRTKIIDTARNCNIPLIIIPQS ->tr|H7FW26|H7FW26_9FLAO Putative universal stress protein UspA OS=Flavobacterium frigoris PS1 GN=HJ01_03373 PE=3 SV=1 -RPIKNIGFTTRYRNKDKKALSSVLEIAKKLNAKVKCLYVKSS-TSDVTCETINLWEKVYGSEPISFEIVNSdDIKETVLAFVSANNIDVLTMLTYKRGFFDGLFVPSYGDKSQYDIDIPILAIHSD ->tr|F0NXI6|F0NXI6_WEEVC UspA domain-containing protein OS=Weeksella virosa (strain ATCC 43766 / DSM 16922 / JCM 21250 / NBRC 16016 / NCTC 11634 / CL345 -KPEKRLGFASRLLEKERRTLEKLIVLAKRNGGPLELVHIAKDNiLDSDAALVKNFWEREFKDDELEITVLVNkDINKGIADFVTQKNIDVLCLIHRDMNSIERIFKGNYSKKLLQSLQIPILVYPEI ->tr|A0A1H5Z6L4|A0A1H5Z6L4_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Sphingobacterium lactis GN=SAMN05421877_106249 PE=3 SV=1 -QGINRAVFTTLFREKDKSALREMLIMSNAIDAKIDCVHVLHNRNVADVLLQTEAWQQEFKDENIEYILLDEveSVENTIANYILENNIDIMGVVKRNRSFFDRLFNSSISNNLAFHSKVPILVFHEE ->tr|A0A1M5HHV0|A0A1M5HHV0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Flavobacterium fluvii GN=SAMN05443549_102240 PE=3 SV=1 -KNIKTIGYVNHYTAKDKETLGVVLDMAKMINATVKSLYVRTH-KSEIDAGTKKKWEENFSEEPIAFFEVRNeEIKQMTLDFISHQEIDVLTMLTYKNNIFEGMFVPTYAKKNVSEFEIPILVIHA- ->tr|A0A1H6S0B0|A0A1H6S0B0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Myroides marinus GN=SAMN04488018_102245 PE=3 SV=1 -KQLENIIFTSRFELEEESTLDDIIKGAEANNAHVKVVHVKSK-GCTSCEEVYNKWKEKYKDSPVSFHLFNAeNIEKTLLDFIEHEKVDTVATIKRNKSFIENILSKSITQHLAKHLKVPFFVYKSK ->tr|A0A159ZVD0|A0A159ZVD0_PSEFL Universal stress protein OS=Pseudomonas fluorescens GN=TK06_07655 PE=4 SV=1 -SQYQRLLLILNPAQRHSPALHHAAALAAASGAHLHVTALIPSLDILslleegpreearqnylqdhrHWLEDEADKMRRRGLRITTEVEWAQKMGKQILQHVTQIQPDLLIKQVQHEPMLKRAFFTPLDWQLLRNCPVPMYLVGAT ->tr|A0A1W9F2R2|A0A1W9F2R2_9GAMM Universal stress protein UspA OS=Serratia nematodiphila DZ0503SBS1 GN=AK51_23625 PE=4 SV=1 -MAYRHIVVATDLSEDAEFLLGKGARLAAALNAKLSLIYIdihragyyvdlgvgdynYTDRTFSERVKNMLNAIKGQSSYPVEEVIVsRGALTEELNRVAKEKGFDLVIFGHHHDVWSR---LVSSARQAINELNVDLLVVP-- ->tr|F4C431|F4C431_SPHS2 UspA domain-containing protein OS=Sphingobacterium sp. (strain 21) GN=Sph21_3250 PE=4 SV=1 --QPKRILGTIDFSKYSNRVYTLGEAFSKG-IPDGRFscihvakapVHFFLGLNQSEINRLLQEETEAkkskwlrqyQIEGKIETVRADGkHIASAILAHAQNYKMDMIIMGVKGSSSLTNLFVGGVTNEIFHH----------- ->tr|A0A0P0NG16|A0A0P0NG16_9SPHI Uncharacterized protein OS=Pedobacter sp. PACM 27299 GN=AQ505_11090 PE=4 SV=1 --KPTKVIEAIDFSKYTAKVMQWGSLIKKYNqIPELTFqpinisklsWKFFPGLSTAEIKKNTQEDLKLksekwaklyPTATPLKVIPAEDkNIASALMYHVKKERADVLIMGVQGVTSVTTLFMGSVANEVLYL----------- ->tr|A0A1W9L9T6|A0A1W9L9T6_9GAMM Uncharacterized protein OS=Beggiatoa sp. IS2 GN=BWK79_03510 PE=3 SV=1 -KHFKNILICTHPEFTDVEIVDRAAKIAKGSGAAVKVMHVIADYPEdmnswwnvrnpkelhekilrerQNFVEGIVERVKAAGVTNIESALRwskEGQEFLVVVREVLKHEHDLVVITSRRKNRLAKLVLECPSLDLFRHCPCALWVTQS- ->tr|B9LQ45|B9LQ45_HALLT Amino acid permease-associated region OS=Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) GN=Hlac_1 --ALDVVNIGAGGGPHHMDLLSLIDRMGER-DAEIHVINITPEGGEG-RPENTEATVSGLPNAsSVQIHnTTAQTIADGLVDRAR--ENGgILIIGATRTRRLRRRVFGSTPDNVIKLAqgsGVPVLVYSSP ->tr|A0A1J5N292|A0A1J5N292_9DELT Universal stress protein family protein OS=Desulfovibrio dechloracetivorans GN=BerOc1_00854 PE=4 SV=1 ---MKNVLIVVDKSESSLWLAYYAMGLTRRMAVNVSILLVVDEEidgragdneewigSPEKRLESILAEGRSEGT-RLDYYVVRGRMEEEIPKFIRENSVTKLFIGAPpSGRRSLYLKLMRVIDAVNTTTRCEVEVVQK- ->tr|A0A1X7DEE7|A0A1X7DEE7_9DELT Uncharacterized protein OS=Desulfovibrio sp. K3S GN=SAMN06295933_1788 PE=4 SV=1 ---MNNVLIAVDTSESSFWLAYYAIALTKRIPMDVSILMIEDENhkiksgkgdewigLPEKRLESLLAEGHSDKS-HINFYSTKGNFEDEVIQFILENKITTLFIGQPePRRAKLDTQFMALLERIGSRTDCHIEVVQK- ->tr|A0A1V5H4Q2|A0A1V5H4Q2_9DELT Universal stress protein family protein OS=Deltaproteobacteria bacterium ADurb.BinA179 GN=BWZ01_01869 PE=4 SV=1 -KKPRRLLCYIDFSDHSYYIVEYAFELAKLVDAELFVLHSvtdikkaagfYVPHINTDLLEDQVAKAARdkmyaichqvvgEEIDADHRLVTQGNPVEDINRVIEEKGIELLILSHEMSRGSLSGFRSDHVERFMKNATIPFLVLP-- ->tr|E4T1V1|E4T1V1_PALPW Uncharacterized protein OS=Paludibacter propionicigenes (strain DSM 17365 / JCM 13257 / WB4) GN=Palpr_0536 PE=4 SV=1 --DLKRVLLPIGFLEEELEKAQFAAAFGRFCNSEIKMLLANDYGSKAAANAEKMKSLFDKFDFKYSLDKATKDsfkVEQESVQLAENMNAGIIIVSASRDYGLDDIIFGPKEYHVVNKSTIPVLLVNP- ->tr|A0A0R3TY69|A0A0R3TY69_HYMNN Uncharacterized protein OS=Hymenolepis nana PE=4 SV=1 ----RSILFPVLDNSVGERLFNWYCQYFRRPEDQLTVLSIVEPTLQMQkagvssddplveaamvvgrnIVRRFLQRAHERSIPCRGVVQLDISPALSIVRTARERGTQIILMCPRGNvaGESEKVEFDSVTEYVLRHCPdIALAIVPPT ->tr|K6YAG5|K6YAG5_9ALTE Uncharacterized protein OS=Aliiglaciecola lipolytica E3 GN=GLIP_1016 PE=4 SV=1 ----LEVLACVDISDDdfdnhvlNRKILAVSDKLSQSINAQMHVIDCYDGEIGTmhidynnkrgfkreatiqqKHIEKLELYIKEYALSNDVLHSVEGLPDEAVPDKAASLNAEVAVIGNNEDKHFMDKMFGDTAMALAEAMPCDILVLKP- ->tr|A0A0K1IRS4|A0A0K1IRS4_9EURY Amino acid transporter OS=Haloferax gibbonsii GN=ABY42_05205 PE=4 SV=1 -----HALVAISHdiSKARERAlIQVASRLARANDGRVTVARFETVPDQtslayasavespadVEFERQTDELDDEFGVPIRCGTIVTHDTRHAVVNYADNQDVDFLLVEHPTGtKRVSERLFGTDTSWILRHAPCEAGLLKGP ->tr|T0SN40|T0SN40_9DELT Amino acid permease OS=Bacteriovorax sp. Seq25_V GN=M900_1362 PE=4 SV=1 -----QIVITLLGKERSPEMlVEMGVALS-ENDDLIEVAHLTEAPEQsdlsdfieeppelKSLRRRVIAMAIEKGKPLTFDPVVTHDISKTIFELSQRMHSKWLFMEWSG-KSRGTITLHSPITWLKAHLECHLVIFKDK ->tr|A0A1H4KZJ3|A0A1H4KZJ3_9BACT Nucleotide-binding universal stress protein, UspA family OS=Terriglobus roseus GN=SAMN05443244_1417 PE=3 SV=1 -MGNDQLMFATDLTERSLEPIPLLAALMTPST-HLTVVHVTESVLEtdaRAAMDTVRARMALYLPDqamkhQVKWKVIHSsEVTKALIEAATEDKAELLIMGMHRSGELNAHLPLKTGFQIIIGAPCAVLSV--- ->tr|A0A1M6JJJ8|A0A1M6JJJ8_9BACT Nucleotide-binding universal stress protein, UspA family OS=Reichenbachiella agariperforans GN=SAMN04488028_101218 PE=3 SV=1 ----GELLVLIGIRDYRTESIARIREFAEVMRMNVHIAHVTEPHDLlhKSISDRLEDFARAHGFTDYKVHVIeSGQKVEQVQAFVEAWHIDVVASISEGDSGIARLIYGSDTEDFINHVDKPVLAVTM- ->tr|A0A1P8XFQ9|A0A1P8XFQ9_9MYCO Uncharacterized protein OS=Mycobacterium sp. MS1601 GN=BVC93_25095 PE=4 SV=1 ------MVVGVDGSAGSMAAVRWAAGEAAGLRLPLRLVYAIDPDDAttalptgtarlrssaQSTLEQAENEAQRvAPQLDVECLMVNGRPAVTLAGLG---RPAMICVGASAPAVPHPGHHANVVTELILAADCPVVVFQDE ->tr|A0A0L0DCK5|A0A0L0DCK5_THETB Uncharacterized protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_06119 PE=4 SV=1 ----NKFLVCVNGSKHSKWAMRYTMEIMQE-NDRLYLFHAYSPKENPKYKDEALALVEElvteakyanEWLSIASILLPTKKVKEAICDMALALDMSFVVLGTTRRARIVSKFAGNTGLHVVHHSPLPVIVVTDS ->tr|H1Y839|H1Y839_9SPHI Uncharacterized protein OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_7017 PE=4 SV=1 ---MKKISVVFDGLKFANNTLTYGIKLGENSNALLSGVflesflynsYTLADlvgtqglsqvkmkhllekdeKMRVKSVEAFEQACKKAEI-NYSVHHHPSFAIPEVLRESI--YSDLLLISADETfSHVADQQPTQFIRELLAGIQCPVLILP-- ->tr|V4BJ62|V4BJ62_LOTGI Uncharacterized protein OS=Lottia gigantea GN=LOTGIDRAFT_165224 PE=4 SV=1 --MKQKILIASDGERDSEWAFDWYCNNLHRPGNNVIIVSCTEIGVklatiapeaiingdetaievfieeenkiLAEKVSKYQKKLRSAMLVGKVLTSCHTSPSEVILNTAASEEVNMIIIGSKG-CGLNRQGVGSVCNYLVSHSTIPVIVCRH- ->tr|L9XA51|L9XA51_9EURY Sodium/hydrogen exchanger OS=Natronococcus jeotgali DSM 18795 GN=C492_12265 PE=4 SV=1 -ETPQRILVPVSSESrHAESLLDLAFAIRDPrVREPVHAVSVVRPESlartrsrvaaAEDRLADLEEYAAGAEV-PIEGHARIDhNVASGLVRSALENRISTLVIGWDGARSREQQVFGHTIDQVLRRTTQLTLVGR-- ->tr|Q8KDB0|Q8KDB0_CHLTE Na+/H+ antiporter, putative OS=Chlorobium tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) GN=CT1144 PE=4 SV=1 -DADEQILLPIAENKPSERVLELAVMIREKrSLNPLTILTVVPNDHeaelnvkkAKKELAPTVDFAASFDT-SLNIVATIDyNICSGISRAVKESQSNLIIFDWPSRQGFLGRMINDATESIVECTCKTTMICH-- ->tr|A0A170YDP3|A0A170YDP3_9PORP Kef-type K+ transport system OS=Paludibacter jiangxiensis GN=PJIAN_1306 PE=4 SV=1 -KRRERIMFTVANPHTLDHLVEFSIAIKNPrSKEDLYALRVVNDNDeahkeqGDRLLLQAAKVASVADQ-WVERISRYDvNVASGILYSAKEYAITDVVIGLHQKLKSRDTLFGLMTEMLLKGVSCSLFIYK-- ->tr|Q3ARA8|Q3ARA8_CHLCH Transporter, CPA2 family OS=Chlorobium chlorochromatii (strain CaD3) GN=Cag_1205 PE=4 SV=1 -APTNRFLLHINHMGTVKELVNVSGMMVTGkMPYSLYGAYIATTREmevnheyrAEKMLERAVISAGAADR-HVTPLLRYDtSIANGLAGVICEQKISDLFVCVEPSSDFPDTLSINKPDNILGRCGVTTFIYR-- ->tr|L1MQ19|L1MQ19_9BACT Transporter, CPA2 family OS=Prevotella sp. oral taxon 473 str. F0040 GN=HMPREF9999_00407 PE=4 SV=1 -EEKDSLVVALANPRMVIPMTNMALMLRSAsATSQLTAVSVVLSD-dteeratAQQGLDYAAKMAATVGV-RMQTHCRRSvNAVTGIVHTAGEHEATDILIGLHQKKSISATFFGKFATDLFDAASQQIMVYR-- ->tr|R4Z0V6|R4Z0V6_9ACTN Putative Na+/H+ antiporter CPA2 family OS=Candidatus Microthrix parvicella RN1 GN=BN381_410038 PE=4 SV=1 -APAEKVLVPVGDPKRSMDVLRLAGMLAAPDTGTVVPVSVLDLEAtqadvkarRAE-LAEAERTILGEGA-EATSVVRLDlTPSAGMLHASVEQAATAVLVGWKGFANRNGSAFGQRVDALLAASPVPVVVAR-- ->tr|A0A1F3JNN3|A0A1F3JNN3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_40_13 GN=A2W88_16320 PE=4 SV=1 -IKEDRILVPVSNPNNLKYLIDFSIILKKSsKEIPIYPLTVISDPKkaqsmmdsFHKKVETYMVDAASTEH-VLHPVVKRDiSVVSGILSAASQNHITRIIIGWNGKITTSNYFLGTLLENLVRKANQMIVVIK-- ->tr|A0A1G3PF26|A0A1G3PF26_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_09390 PE=4 SV=1 -DNTGTFLISIANPVTAERLLDTTILLSNKnSV--INALSIVNDDYntsqniisSKKFHDLLQEKNITANR-VINSVIRVDiNVAGGIIRASKELQTRTLVVGQNRKEKVSDLLFGSMMSKLIDQHPYRIIMCN-- ->tr|D7BNJ2|D7BNJ2_ARCHD Uncharacterized protein OS=Arcanobacterium haemolyticum (strain ATCC 9345 / DSM 20595 / NBRC 15585 / NCTC 8452 / 11018) GN=Arch ----MSVVVPIVQGNRCSQIINRGIAFAESHDVPVVVLlstslDTTTQDDIDDEIDHLTDLLDEKDVAfRIVTRLDNADLATKIRETAIESEASIIIISLAPKPHHGSYQLGHQVQKLLVDAPCEVLVMRDT ->tr|M0NDS8|M0NDS8_9EURY Cationic amino acid transporter OS=Halococcus thailandensis JCM 13552 GN=C451_03784 PE=4 SV=1 ----ARVLVPIHEwlpLADAERLLETAAAIAREQDAEMLVASLAVFARQtpldavqdnedaalaaRESAQEYVETAREFDISASGVAVLTHDETHSILELIEERECDGVILAVDPTTtQRRRLLSGDTVESVVARAECEVFV---- ->tr|A0A173MGW9|A0A173MGW9_9BACT Uncharacterized protein OS=Filimonas lacunae GN=FLA_2882 PE=4 SV=1 ---MKKIIAAFDGFDYSTSTARYAIQLCKECNAHLVGVFLDDVTYhsyklsEItgnggirtekwdmleagdkekreEAASNFEHACQQAKI-EYSIHHNKYVAIHELLHESI--YADLLIVNKTeSFSAYDEKTPTFFMHELLSNVQCPVLVTPLT ->tr|G8TNF4|G8TNF4_NIAKG Uncharacterized protein OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_3571 PE=4 SV=1 ---MKKILLVLDAAHIDTEIIHFACNFASLSHSTLTGLFYGNYEEEQpevkmefgapyieeppvysmgpnitlqqleEHMTQFKSTCAVRGV-RCDVHFDNTSYGsESIITESR--FADFLIIKASaTRERKLKDTPTPFVKDVLAAAECPVLVAPAS ->tr|A0A1A9HZZ0|A0A1A9HZZ0_9BACT Uncharacterized protein OS=Niabella sp. BS26 GN=A8C56_07425 PE=4 SV=1 ---MKNILFITNAVSMNWKVLDFACFIAGAAHSSLKGIFVEVATVSKtyilesddeppcgdilggsdimgfetrqgrkdTNIQRFKEYCEKKNI-PCSTLCVEGEPMKAVLVESR--FADLIIAGAAtSAEENRNQFPAEFMKRLLQKAECPLIIAPDH ->tr|A1S3H4|A1S3H4_SHEAM Uncharacterized protein OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=Sama_0722 PE=3 SV=1 -GHFSRVLVATDDGLHAKPALRKAVHLANQSHADLTMLRVQLPKQAGlsqwlqqlltAPNiSHQRQKHPSYPDKDIRLVLKhchAPTLANAVLDELSQRDYDLLILEHHEYSALRCEFGHTEDWQLLQQVPIPVLFVSNE ->tr|B1KGK6|B1KGK6_SHEWM UspA domain protein OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_1041 PE=4 SV=1 -SSYQHILGVFSPYLSSQHALIKALILADKSKSKLTLIQLTTPKFNFmkstnnstdmQPLAENEDLIFQYQNLGLEIEIKevkSNSVSTEVLAEVEQAQYDLVIVNYKHHHPIFHEFFFAEEWSLLRQKQISVMLVGDK ->tr|B8CJZ1|B8CJZ1_SHEPW UspA (Universal stress protein) OS=Shewanella piezotolerans (strain WP3 / JCM 13877) GN=swp_0886 PE=4 SV=1 -ISYHHTLALVDNNSVAQFALNKALQLACKTKAKVTALKVEKPYNNFlnrlglipdnalDPMLFVNKLLSKYQRLGVEVEVKqikNTKDHIAILNETNASDYDLVMINNQHHNTIVSEFLPSCEEHLLRESNLPILIVGNK ->tr|A0A1F3KIP4|A0A1F3KIP4_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_35_48 GN=A2X01_14975 PE=4 SV=1 -CNMKNILIPTDLTDCTKNTISYAIALGVKSNTKLFFYHTETSQERSNkeyaikfIKDIFNEQHLNFEKSQVEFIIEnVAFSNAQIKSTIEKFNIDLVIMGASH-EGLKTTFFGSHVSKLINDVSCPVLSIPHD ->tr|A0A1U1C454|A0A1U1C454_9MYCO Universal stress protein OS=Mycobacterium abscessus subsp. abscessus GN=SAMEA2275847_02068 PE=4 SV=1 -LRIREVTCAMGTRPGARVLLDTALRICKRAETPLRLVSLVSIDPIpggdddqsarERATIHAQQSLETAKLVlppdfPVTSTVAEGPTVEAAVNKLDWHEGDIIMVGSSRLAQPRRLFLGSTAAKMLRVLQVPMVVIPKE ->tr|F8UI20|F8UI20_9ZZZZ UspA domain-containing protein OS=uncultured microorganism GN=LDC_03295 PE=4 SV=1 --MLQRVLVVFENEKVSEKALVYARELALRMDCEVTLLMLVEMPFQNgshlapkreaireiekrmgKVLAERSAEFLKKGI-VVSAALRIGAPAQELMKFlAERHPFQVVIWGGADDFTERgSVPKNHWMNKMAAKLEGSLIIVSH- ->tr|A0A1W9PS81|A0A1W9PS81_9DELT Uncharacterized protein OS=Desulfococcus sp. 4484_241 GN=B5M56_09520 PE=4 SV=1 --SPKWVLLVLEDGMVPEESLCHTIGLARRLGCSVSVLMLMEENVYGtpagyeqgcKDLEQALDRIRSEGL-DVRHSLEHGEKASGLLKHiALIPSLSALVWGGKEDIASTrkKRKGDHWFERVRPAVPCPIVSPRV- ->tr|A0A1P8WKS5|A0A1P8WKS5_9PLAN Universal stress protein E OS=Fuerstia marisgermanicae GN=uspE PE=4 SV=1 -HSVKKITVGVEMPEtrpwnaaniaaPSRLAVRQAFGVAEAMGVAVTLVSVLPEISYgffgsdeavesqaetdrteaAAVLEDLKQQYSEKSSRplEVTTTVAFGRPWFQILKAAGTARDNLILCGTRHKGAVSRLLFGSTGLKLLRNAVGPVWLVNP- ->tr|H5SES2|H5SES2_9CHLR UspA domain protein OS=uncultured Chloroflexi bacterium GN=HGMM_F17E05C18 PE=4 SV=1 ----LKLSVYTNGHSATWPALQYGAHLAEALGQPLQLIAIDESDQpllpeaahpLEAFLEQARKLFQEHHV-MYELEIHRGHAEDIIPARVNASAEGLHLVAPLGRPPLRRLFWGRSFRHIMARAVAPLLYVP-- ->tr|A0A0P6Y2Y7|A0A0P6Y2Y7_9CHLR Uncharacterized protein OS=Bellilinea caldifistulae GN=AC812_00130 PE=4 SV=1 ----PPLLIALQSSHPSFPALEYGENLAKVLRTPVRLLCMRQAGSsalLEEQVQRSALALKELDV-LVDIRWADGDLVKAVLREVNQMPEAMLVISDKYRPIWRRWVRFGRFRRLQASLTSPILRVR-- ->tr|A0A1J4ZKY6|A0A1J4ZKY6_9CHLR Uncharacterized protein OS=Anaerolineae bacterium CG2_30_57_67 GN=AUK01_00785 PE=4 SV=1 ----PKLCVFTNGFEGNWPSIEYAAWMAEAMQAKITLTGTQEKDAenfsVEAIFSRAVSLFQQKNI-DYALNLGDDSIENLMARTAQSDSDALFVFSPLGRSRLRRMAQGRSFRQIMVQVDAPLLYVP-- ->tr|T2G8H3|T2G8H3_DESGI Putative UspA domain-containing protein OS=Desulfovibrio gigas DSM 1382 = ATCC 19364 GN=DGI_1013 PE=4 SV=1 --MNRHFLVTVSDDPQAMHAIRFLGHFFHrKDGLECTLFYVAPRDHDsptamikpdarelakgTAALEAARDKLHHMGWPaehlHIKTMTQRQSRAMEIVDEASRGRYDAVVLGRRGITSFEAFMGSSISHEILEERIsFPLWLCRM- ->tr|G2HBX5|G2HBX5_9DELT Uncharacterized protein OS=Desulfovibrio sp. A2 GN=DA2_3282 PE=4 SV=1 --MERHLLLTMGGDGGESWNLRFVAGFFRnKSSLRLTLFYVVPDAYSsglgevilsdaqmrqgMEQLARARKWAVEHGFAsenvETRAVPRQFGVVRDIVEEAHRGMYDAVVSGRRYLGWLEQTYTTSVSRGLLGEEIaFPLWVCHQ- ->tr|A0A1Q9S2U0|A0A1Q9S2U0_9PSEU Uncharacterized protein OS=Pseudonocardia sp. CNS-004 GN=BJF90_24850 PE=4 SV=1 -AGTGRVVAAVRDLPNDVAVLTEAALAAMALDATVVPVHCVPLSFGErsvgltdalarghEVLDAAVAQLAADaPDIPVAPRLLRVHPHELVGEGL---DADVLVLGGPRQRIPAR--VGLVGCSAVQHAPCPVLLAARP ->tr|A0A1F9ASE0|A0A1F9ASE0_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_52_11b GN=A2162_06210 PE=4 SV=1 --KIRKILIPFGTSIHTRLATEIAPALGAHFGAKLSVVVVFDPDTPvygrDKRLSEVRQVMEQSSVWADLKVVTEKDVLKGVLKEAA--DADLVLMGGRTGDFLELLLSKSLSEEITEQVKCPVLWVRE- ->tr|A0A1W9PS31|A0A1W9PS31_9CHLR Uncharacterized protein (Fragment) OS=Anaerolinea sp. 4484_236 GN=B5M51_08395 PE=4 SV=1 -RTIEKVVILLDGSVYAAQAIPTAKRICRSMGASLTLLSSVKAYSHgpqeqfeaelssrEGYLAALVQQMRSNDY-TVDYAIRRGSIAEVTHAFVEANDIDLVITTTRGKSGQKHWMKGGVSSKLMSKLSIPVLLVQGE ->tr|A0A1A7V2K6|A0A1A7V2K6_9VIBR Universal stress protein OS=Vibrio mediterranei GN=VME0621_04734 PE=3 SV=1 -MKYKNILLAIDFEHSDAELIKNATDLAFSLGATISLVYVHPNVEYNpyslaywgdiyrefvaeleqkHDTKELEFIVSAYPISKENIYIKNGDVSREMHAVIEIVDADLIILGKHHS---VVNMEGTLERSMRSVAGLDVLLV--- ->tr|A0A0G3ED81|A0A0G3ED81_9BACT Universal stress protein family protein OS=Verrucomicrobia bacterium L21-Fru-AB GN=L21SP4_00017 PE=4 SV=1 --MSAPVMLALSTFRQSDKAVSRAVDRAATENRPLVIVYVVDVNLARyfigtdlgmypelqqryeddvlrehgriaaERMEHIIREAQDHGV-EVRSAIHTGRFAKECLRIAAEERPSVIITTRSNRPQWVKHFFGSPVDELEESADGPVEEY--- ->tr|A0A162HG07|A0A162HG07_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium GWC2_55_46 GN=A2V21_202245 PE=4 SV=1 ---MKKVLLVLSGHAKAQEAVTFAVKKAKDCNGALIALYLLETGAAsdvfdtftdigfigdkpsaqvseaimkeyrqrgYEELGKVQIKAMEEGV-AFEPLLERGEPVEKVLSIIEKMEITTAVLVKRKRRAFFKYFSRSFADDIAEKASCEVVVF--- ->tr|A0A1G1IJ80|A0A1G1IJ80_9BACT Uncharacterized protein OS=Omnitrophica bacterium GWA2_50_21 GN=A2036_00800 PE=3 SV=1 --PFRRVLLASAGGRLSDRALGIAVRLGISGSCKVEVLTVSPaSSPALRMVHDKAKYFFDKYNVKATYKIEQGHMKKTILRSCESKETSLLVLGANETDHWKDHRFRSFSEDVVDAAICPVLVVK-- ->tr|A0A172TWW6|A0A172TWW6_9BACT Uncharacterized protein OS=Flavisolibacter sp. LCS9 GN=SY85_14040 PE=4 SV=1 ---MNKVLLILDGLQVPGYLMDAAANIGKMAN--CHIHAIFLNKAPIdpeynyffpndlilvdnplrgeniaaenseiisATIQTFKDVSDLAGL-SYTIDERNDYSLDELLELTA--FSDLLLADAKSNfY-------EYLLSDLLTDSHCPVLLTKQT ->tr|H8KQC9|H8KQC9_SOLCM Uncharacterized protein OS=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) GN=Solca_14 ---MKKIVLIFDGSNFSEAAFDFACHMNSMNP--VLLTGVFLSNRDYatafqygfggglvftdwglgeddeqrakISIKRFEALCLNNGI-DFRIHNGLgAYALSEINKESR--FADLVIISSDLFyKNVGGEQPNEYMRSVLRDTECPIILVPEeK ->tr|A0A1Y2K4C2|A0A1Y2K4C2_9PROT Putative UspA domain-containing protein OS=Magnetofaba australis IT-1 GN=MAIT1_03663 PE=4 SV=1 ---MKSIIALTDLTDSCKPVIALSEELAKGMGWRLYVMHVVPPHDAKggpayvgnevddgqprrdaaaalkelrHKLHAQRDELIARGV-DCHAVMVEGQLEEKLLKEVDAINPEFVIIGRHCHDMLYKVIFGNRSDKLLDKLKQPLMVVP-- ->tr|I4ANH4|I4ANH4_FLELS Universal stress protein UspA-like protein OS=Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / S ---MKTLLVPTNFSLSSAKSLQYSTLLAKEFGSKIIVHHTYPQNSPVHWLSDLENQLHAfvseydfehytgsEDYLKIETSIQQGREKENIINIIKKHDADILILSAKDRTQWEGIPFEMLISQTLEQTLSSVLIVPSE ->tr|F4QTG9|F4QTG9_9CAUL Universal stress family protein OS=Asticcacaulis biprosthecum C19 GN=ABI_44660 PE=4 SV=1 -VSPKLRLHLFGGHAHELNALSLALAMARHDGAHLRILHIAETPFLPeisglgaygagaeanlhepdhvQLAQDAAAYVRAyclhekvpllrpgdspvAGQASAEFRNVSGTPATVVMQQAL--SCDLVVSDWNHQPD----EDLSTTRSVLFGARRPIMLLPR- ->tr|V4R5S4|V4R5S4_9CAUL Uncharacterized protein OS=Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896 GN=ABENE_17820 PE=3 SV=1 -MSIKSILCVYSGNADEANALITAFNLTHTVKGSLRVLHLAEPPILYaatigagyasgqypdgaavkileqsarELTETALKSVTNlsqahsvelvedsvkavAGLAQASFRTLVGTTAECLPKDGR--SVDIIVVGYDNSPD----GNLETVLTALFKTGSPVLAIPR- ->tr|A0A075AYS1|A0A075AYS1_9FUNG Uncharacterized protein OS=Rozella allomycis CSF55 GN=O9G_004665 PE=4 SV=1 ----RSLIMAIDNDESSLKALQWCIKNNFIHSYDnLLLVHSIESGEtkinqeslvdfkacaggdvqsFFKSFNSVCEQLKVNGiFDNAKLLISNNSIGEVLVESCRKFGAELLIVGSKPAGSFIRALAPNVNDYVVRHATCSVLIVKTH ->tr|F6DVC5|F6DVC5_DESRL UspA domain-containing protein OS=Desulfotomaculum ruminis (strain ATCC 23193 / DSM 2154 / NCIB 8452 / DL) GN=Desru_2024 PE=4 S --MYNNILIAIQGEEG-PQFLQKALELIHPAQGTITILHIKETGLTHygyvdqlassiskeqfidyihelaenqqkKIQEQIIEQGDRWNL-NFAWRVREGSPAQELRKEVAALNYDLLILGTKPKAPGNT--SSKVKEAMLKVFDGSILIIK-- ->tr|A0A0D3L9X6|A0A0D3L9X6_9BACT Universal stress protein family protein OS=Flammeovirgaceae bacterium 311 GN=D770_02370 PE=4 SV=1 --SIDAMMVCLHLSDIDNKLVAFTQSICQRLQVKkVYFVHNVKTAELSEDFRetfgdvdlskeveaSIADIVAEHftGGCEHEILVSEEPNTEMMMTDlVKRYGVKLTLLGKRMSEKS----TGALGTRLLHILPCSILVFPET ->tr|A0A1N7CN11|A0A1N7CN11_9EURY Nucleotide-binding universal stress protein, UspA family OS=Natronorubrum thiooxidans GN=SAMN05421752_101464 PE=4 SV=1 -RMCMNVLVGLVGSDESIKTLRRTIDRTEEVGDDLTVAIVDKPEakrSQAEMTQQAETLLTDAAV-DAEVITLEGDPGSSLVDYAEQGEYDQLVIGGGTLSPMGKIQLGPITEFVLLNAPTTVKLVR-- ->tr|M7N2R3|M7N2R3_9BACT Universal stress protein family protein OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_03292 PE=3 SV=1 -RRPRKLVFATDLKPFdNPKPVENLLGIARWLQTDIVLLHVHESREGLSPKKEKELQQLQGYfqQQPSVVLQQADDKEEAILQLARQEQPDWLMAVSHHYGLLEGLFHSSLTKKLARETDIPLLV---- ->tr|L8JLT6|L8JLT6_9BACT UspA OS=Fulvivirga imtechensis AK7 GN=C900_00446 PE=4 SV=1 -NQAKGILVPVDFTEAARHAVMNAIELAKQLNTDVYLVNFIPPVkkkrvrkagadieaisidlsssinllrENEQRLADMLKEMDKADV-TVHSEIKIDKLASGVKKQLKNKHIDLIVIGITEAHTVGDSFYKASKARDLIEVTCPIMVCNNH ->tr|A0A1Y0H995|A0A1Y0H995_9BACT Uncharacterized protein OS=Armatimonadetes bacterium Uphvl-Ar2 GN=CCB81_08315 PE=4 SV=1 -------VFASDLSPYSQKAWQQFGRMQAHGLSKVIAVTVVDTRPVDfgpllpdptpfmpnlpvldrdALLQRLKEACPAPAGMNVEHVIVDGTPAESLEPYMQSVGADLLVLGAQGHTWADRVAIGSVALHMTMWGSSTLLLVRP- ->tr|A0A059LNL4|A0A059LNL4_9CHLO Uncharacterized protein OS=Helicosporidium sp. ATCC 50920 GN=H632_c551p2 PE=4 SV=1 -PPPRRIAIAYSSFAVGRALMAFARERLLTPRDAVYVVHSFPRESQPgalagnvmaqtrklvramtlsrtlspdapadrgrhAVTEDNSMDFGAAELAGYDVQLGVvlrGDPRHALAAFCEAEAVDLLLVGARRGSRLRKSLSGgSVSAALADSGACPVLVVP-- ->tr|A0A0S8AR74|A0A0S8AR74_9BACT Uncharacterized protein OS=Nitrospira bacterium SG8_35_4 GN=AMK71_06125 PE=4 SV=1 ----RTIMLALTGDSEDEKAFRFAINACQRVRADLEILYSGQKKDR--VPEWIRSELRSEGIA-YSFIKVDGCVREAVQKHTAkRSDILFVVVESSDRLHMECKKSQKMISKSWKDLQCPLVVVSEL ->tr|A0A1G1GZP4|A0A1G1GZP4_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_57_9 GN=A2078_04815 PE=4 SV=1 ----RRVLLALKQGRIDAKTVKYAVNSAKRIGADLDILFVSSSEGQADpLLEELESGLTAEGVT-YRLIRKQGCLKEAVIDYTNrEKEILFAVVESPESLDADCRKKDSMLSELWQKLKCPLVVVMDQ ->tr|A0A1F9MMV7|A0A1F9MMV7_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFOXYD12_FULL_53_23 GN=A2520_11300 PE=4 SV=1 ----KRVLLGTDKPELATRTISYALHLCQRLGGSLEIFHMLRLPENETehlmrqekePLAALNIALQQKGVV-YQPINGPGCLADEMLRHASvRRDILCVVFDALEPDSAICRKAKENMIAKFQALHCPVVMYAGS ->tr|K0PQM1|K0PQM1_9RHIZ Uncharacterized protein OS=Rhizobium mesoamericanum STM3625 GN=BN77_3294 PE=4 SV=1 ----DHVLIGWKPHEHSRRTMVAARRWLVAAN-RITVLCVDDM-PSRHYETTAREICRHLGVEaeIVVTSSAGRSVGNTILDFGTSVNASCILIGAFKHGYLLELLLGRVTYRLLSHANVPLLM---- ->tr|A0A099K829|A0A099K829_COLPS UspA domain-containing protein OS=Colwellia psychrerythraea GN=GAB14E_0779 PE=4 SV=1 -KFIKSILVVMDDNSDRQTALIQAINIAEKTSATIELFLVVYKNEFvshwnfnqeqldalqkeyiaskLRWLETYLPEVKALDIV-VHFDVVwHADVSCAVLTKAAKVNASMVVKSTQKSSMINKMFFTPCDWQLLEHCPVPLLLTKN- ->tr|B3PLH3|B3PLH3_CELJU Universal stress protein family OS=Cellvibrio japonicus (strain Ueda107) GN=CJA_2593 PE=3 SV=1 -SKPEKIFVVVDPNDTTHIALERVIITSTLRDVkpKVHAFVAVDPNAVDTrtvnenvfrdlswFESAIKNPLINAGI-DFNLEVSwSSEWQKSIMESAKRFDADLIYLPVHATTASSRFLFTESKWELLKGAYCPVVLIRPG ->tr|A0A0F2NXK8|A0A0F2NXK8_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium BRH_c0 GN=VR73_09865 PE=4 SV=1 -ALEEKLLIVVNPAASKQPALDRAVNIAqA-giYEFspEIHLLVTVDQSSTDAradndavyrdgqwLNA-VTQQLQSGGI-EPHIRISwSKDWADSILYSAGVLGVSSIVVSHPGK--SANRAFSDEFWYLVRNAPIPVSVVQSA ->tr|A0A0E0QZH8|A0A0E0QZH8_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=4 SV=1 -----------DGEANARLSQRWGWSAVYGAASMMEAVRAAQAENARNLLVRARLVCERRGVA-AATVAVEGEPREALCRAAEDAGAGLLVVGSRGLGALKRYAHAVTHTPHAHAHTTS------- ->tr|A0A077ZYH0|A0A077ZYH0_STYLE Universal stress protein OS=Stylonychia lemnae GN=Contig6737.g7209 PE=4 SV=1 -------MVAVDGSEASHNAYEVVTqSLFHFPEDILTIAHVFNRSKSYlpfnmhaDTIRQTYDSLIIGYGARAKLLWEENDPQyttkEHVLNLAKSNNVDLLVVGMHGRKGPKAdpTVLGSAVQHLSLNTFCPVLMLKD- ->tr|A0A1L6L4G6|A0A1L6L4G6_9DELT Universal stress protein OS=Minicystis rosea GN=A7982_01999 PE=4 SV=1 -SSSRAIVAATDFSCATFPTLTRAFELGARLHAPVTFVHSVDTIMALvasstfgvaavmlggmlrdavaKRGEILQNVAERLGGGVDTIVLARENAAGAILEVARQRDADLIVVGSHRPDALGWLASGGTVEAVATTARRCVLTVP-- ->tr|I7M3S2|I7M3S2_TETTS Universal stress family protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00459310 PE=4 SV=1 -----NFLVCIDGSNKSYKALNYALNLAQNPNDKITICYAPTPDKQkftRTIDAKLQEDLEQAKHINWKFVELTPsyNATEQIIKHVNscgnEDQFQFVIIGNNGYRAQieDKSFFGRTAEEITIHSNSNIIIIT-- ->tr|I7LX58|I7LX58_TETTS Universal stress family protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00657540 PE=4 SV=2 -----TFLVGIDGSKKSLKCLHIAASLANNPNDKLIACFAPSPDRIkqiDEINQKVQNEMAQINFQNWQYVSLQPnyDSGEAIINYVNlneEVDVQFVIVKYNLYLCIkvIELFLTDRQQRFQSRKRKESILWQ-- ->tr|I0IAW0|I0IAW0_PHYMF UspA family protein OS=Phycisphaera mikurensis (strain NBRC 102666 / KCTC 22515 / FYK2301M01) GN=PSMK_02390 PE=4 SV=1 ------MLVSVSSPWASEKLVGPIADLAARLNAEVLVAHVATLQDDDDAESDATERgeqtlglltkgLREAGVECDGVMLLSDDTPKAILNTARAKGCTCIVLGLTGKGVLKRLIAGDVPANLIRQTDLPVLLLPAN ->tr|A0A059LE41|A0A059LE41_9CHLO Uncharacterized protein OS=Helicosporidium sp. ATCC 50920 GN=H632_c3150p0 PE=4 SV=1 --------------------IWSIKNLRPEPKGGLYVLHVLpdmfaspaagpayfgdaaDPLVEDALLREAWANLEDvfvskgrqMGVEVTPVLIKESEtkhVGSALVKKAEELEACPLVLAKHTKPNWQQVLLGSTSKFCALNCHRPVLLLHP- ->tr|A0A061SK27|A0A061SK27_9CHLO Universal stress protein OS=Tetraselmis sp. GSL018 GN=TSPGSL018_570 PE=4 SV=1 --MGKTVMICVeDHFKSSRPAFEWSLNHIVEEDDELHVVTVLPSMAYSavtpavplatagavtavtnqweaqrrvseehaaETLKEASQVVESHNLKlkGFHTHALPACggacgAGSTLVEYANSRHIDVAVLGSRGHGAFKRSLmsvvgLGSVSDHCVHDLHCPVLVVRQG ->tr|A0A221T141|A0A221T141_9DEIO Uncharacterized protein OS=Deinococcus ficus GN=DFI_15750 PE=4 SV=1 --MIQRILLPLKDLTGDPWPLHWTRQAF--PHVDLCLLHVLVPERREltpfpmmaygsalsttrtaaSSVMRAIEVREALRWLGHGEVILADQAAPAIVQYAETGAFDAIVLGRgpSSRGALERVLGGSVTARVARTAPVPVLLVPEG ->tr|A0A1Y1WL25|A0A1Y1WL25_9FUNG Uncharacterized protein (Fragment) OS=Linderina pennispora GN=DL89DRAFT_202430 PE=4 SV=1 ------VAIAIKDSPQTIDIIEWAIRQALVPGrDKVVLINVRPAVNGLigdlvssnsdkevaerekshELLKKYASIIKAEGYPIKGVSIRSVDIRGELVRKLMELKCDVLIMGRNASKSMKGRFIGCKVNYLIENSPCPVTV---- ->tr|A0A150GUF6|A0A150GUF6_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_7g945 PE=4 SV=1 -----HIAVGVDGSQMSNLAMNTALGLFNsRRGDKFTVIHVSDssktylskhlqPSHLKNFYTDMAHGARVTAEWLCREKEEGRSTCECLTRLADRHAVDLLVLGSWGRKGEKIDMLGSVSSFSLRQAHASIAIVRST ->tr|D8UBU5|D8UBU5_VOLCA Putative uncharacterized protein OS=Volvox carteri f. nagariensis GN=VOLCADRAFT_107074 PE=4 SV=1 -----SIACAVDGSQMSDRAMAVGLSLFNnRRGDKFTVIHISDatktylskhllPPHLKNYYIDMAHGARVTAEWLCREKEEGRSTCECLTRLADKRGVELLIMGSWGRKGEKLDVLGTVSDFSLRQSHCSICIVRST ->tr|A0A1Q3QKI2|A0A1Q3QKI2_9BACT Uncharacterized protein OS=Acidobacteriales bacterium 59-55 GN=BGO25_01670 PE=4 SV=1 -FSFDSIIFATDLAPDAARKAALAVALAQDSLGKIYLCHFMQHPGRTSpdasaqrlKFEAALEKLVpalSYDWCYSNCIVEYGEAASRILDTAKRVKAELIVLGAKKGPRLLTRFEDGIVSNVLALAECPVMTI--- ->tr|A8M6X6|A8M6X6_SALAI UspA domain protein OS=Salinispora arenicola (strain CNS-205) GN=Sare_4576 PE=3 SV=1 --QLRHVRGFVTAGIRSPTGAGsILVAAAREARWRAGTLIAVHARPLgnvdAQLLHAATARLNDQGHewlaaqlaatgVHAVPEVVVGAPENALLQHSA--HAALLVLGAHQSSGLWTGQPGTTITHCIRQAPCPVMVVPN- ->tr|A0A0S8AI22|A0A0S8AI22_9DELT Uncharacterized protein OS=Desulfobacterales bacterium SG8_35 GN=AMJ60_06580 PE=4 SV=1 ----KKVLVVLEDEDLNLRLLNYAHDLCKRLGGQLEILHKQGPGREDISRSEILQEItkSKDDIV-CTSLAPSESLDDKLIEYGRkRRDILCVVLRIDLMGNKPvkKMKENASSPDWImQKLNCPVMVYS-- ->tr|A0A023NS95|A0A023NS95_9GAMM Uncharacterized protein OS=Dyella jiangningensis GN=CH75_08325 PE=4 SV=1 --MFKDISVLMMGIASDEALLAAAAQLSRHFQARLSPIQVVDLPELpyntwailpdpgitkahdairqqaAELAERAGRQLAGMQLdaAPFQRMEAlYTDPWTVAAKECF--CTDLIIA-GRSGTGPPAQRETQGIATLILQSGRPILLLPGE ->tr|A0A0Q8DA66|A0A0Q8DA66_9GAMM Uncharacterized protein OS=Lysobacter sp. Root604 GN=ASD69_05405 PE=4 SV=1 --MYKDLMIPMTGAGADEDALALAIALAKSHGAHLTVLEMVDLPMPlthpwglmpdatmyeahailrergAKNLARLQARLAVESVsSEARLIEAlYSEASRSAARHAY--DADLTIVAGAVGDNADSVVPHAYFVDLLLESGRPVLVVPPR ->tr|A0A1Q3SL13|A0A1Q3SL13_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_01720 PE=4 SV=1 --MIRTIVVPVDRTEEAKPILNIAAWLSLLLGARVRLLGISNETPlsvkeihpphgditllegsdvyrerlnnqlpyplylqekaetpveevtfsseeeqdMENYLSHLQEELTGSylhyvlPPGRVSSCIEKGPVAQALKDLGREEPIDLVVLPSHRENVLHQLLFSSQPNRVVRQDQLPVLVVPQN ->tr|A0A085TT37|A0A085TT37_9RHOB Universal stress protein OS=Thioclava atlantica GN=DW2_15500 PE=4 SV=1 -MIPKTISTAFLSSSETRWLAPAAARLCRHFDAHLVGVHGLGPLLPMggdlvsdpvilpemlewqsqeaEAIRETFEAALKAEDIAGEFRSPADDgdaREDFLIDGCR--SADVILSAHIP-RQGGRANDIRLQEQLIRQAGRPVVVMDEA ->tr|B1KGK6|B1KGK6_SHEWM UspA domain protein OS=Shewanella woodyi (strain ATCC 51908 / MS32) GN=Swoo_1041 PE=4 SV=1 -----------------KKLLDDSEEIASLLDNNIHLINCFHNNNLSmevsisnstvnhrdtkaQHWLDLIDSAQDYDLEDEQLHLIEGLPDHIIPTIAEQYHVNMVIVGASEHQGWLSQLKGHTSEQIIDQLHCDILAIKPT ->tr|A0A0M2PX44|A0A0M2PX44_PROHO Sodium:proton antiporter OS=Prochlorothrix hollandica PCC 9006 GN=PROH_00765 PE=3 SV=1 -QQIQRILVPVkDLLPRTLRTVRFAQWLGETNGGTVVLLHICVAWTPPEQITAFETSLNQWveqqsgtLNPgrsggetlepnpgatvqvtTLTGESiTGEEVASIILNQAQ--QFDLVVLRSVRRRTAGGFAVSTVTNQVMDNFGGSIVLF--- ->tr|Q3AX75|Q3AX75_SYNS9 Possible Na+/H+ antiporter, CPA2 family OS=Synechococcus sp. (strain CC9902) GN=Syncc9902_1401 PE=3 SV=1 -QPLGRILVPIkDLSASAReqfeLALRVINSSPNLHRTRITLLHVHDPRSDHQDRTWMEEQLIRWrpaaipAER-FHTVLvRGPGIDGAIHRLSR--EHDLVILRTQRRRVaGLPIPGSDRTSKLIKQLPCASMVI--- ->tr|K9TE37|K9TE37_9CYAN Kef-type K+ transport system, membrane component OS=Oscillatoria acuminata PCC 6304 GN=Oscil6304_0661 PE=4 SV=1 -VNIHRLLVPVkNLSPQTLRTVRFAQLFADANSGEITLLHVCARRTPVEQIHRFETDLARLvkrdnssIK--ISITSiPDDDVVKVIMKAAQ--SVDMVILRSIRRRTAGGLTVSNVTTQVIEELKCSLILF--- ->tr|K9WKA7|K9WKA7_9CYAN Kef-type K+ transport system, membrane component OS=Microcoleus sp. PCC 7113 GN=Mic7113_4564 PE=4 SV=1 -KNTGRVLFAAaDQQTSL-vafqQTVTLAKNIA--TELKATLELVMLVTSPGSSPFNP--ESVGLSSD-TPVSLIRGNFVRKVSQMLQ--MDDLLILTAHTQPNsLLGLPGQLVQPeAIARIHPDTSMIV--- ->tr|A0A0W0ZCF7|A0A0W0ZCF7_9GAMM Na(+)/H(+) antiporter OS=Legionella steelei GN=Lste_3088 PE=4 SV=1 -KGINRVITVIgAHAIGV-kfneQYLDVVVDIS--KALGLPLTIMTTNYYHNKLNSKF--EKI-KDLD-FQFIKINGDIIEAVSEMAK--ENDLIIIPSMNLQK-RFDTNKNHIPyALLQQ-TESSLII--- ->tr|A0A1F8KUD7|A0A1F8KUD7_9CHLR Uncharacterized protein OS=Chloroflexi bacterium GWB2_54_36 GN=A2X24_05865 PE=4 SV=1 -NSVQRVVVVIpSNTILP-vtigRTMELVSTLS--KAVNVPTLMLVDRSYQEKMTGLA--KTIEVNQP-IEIRQIEGNLLQFILHQVD--EADLIVVPSSGSRK-IFQSKLGDLPeRLTQTVAGN-VMV--- ->tr|A0A1C4DAB2|A0A1C4DAB2_9BACT Transporter, CPA2 family OS=Chitinophaga costaii GN=GA0116948_105164 PE=4 SV=1 -NITQRLVLVLpHNACYE-agfqHYLQKAVMLS--KQAGARMVVCCTPETRVRIEAWLRATRTSVSLT-YRAFGEAEDLL-ELAGELS--DDDLLMMVTARKGTLSYSKYLDNLPaRLSRSFKNNNIIL--- ->tr|A0A1D9PBJ6|A0A1D9PBJ6_9FLAO Sodium:proton antiporter OS=Flavobacterium sp. PK15 GN=BIW12_11120 PE=4 SV=1 -VLHKRILVVVpPLAEHE-ngfdLWVVKIAKLA--QELSIPLFLECNPATQKAVEKFSVEMKLNIKMT-INIFEDWEDFL-VLSRKIN--EDDLFVLISARKGSASYMNLLEKLPfKLGKHFPDNNKFV--- ->tr|A0A1F2X9Z6|A0A1F2X9Z6_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_16_68_21 GN=A2Z12_07940 PE=4 SV=1 -RRI---VVAAgNGETSAAlplrDAVELGVR------LRSGG--VPLVILSDDLAVSR--AVLGVHHH-KHLREVTGDRIDAVCSVAT--DGDLVILPGPHSDRdGA---------ALAQRLPAVSLVV--- ->tr|A0A1Z4JMC2|A0A1Z4JMC2_LEPBY Sodium/hydrogen exchanger OS=Leptolyngbya boryana NIES-2135 GN=NIES2135_47710 PE=4 SV=1 -SQFQKILIPIeNLTLRSISALQFALNIATATNGQMTLMHVCGRTTSASKIAWIRSQLDLLveklapqVEQiATEIVIiPEDDIGRAIVAASK--SFDLLILRSSQTPNtAGGLILGNLVSQISVQIQCSMILF--- ->tr|A0A136L0F9|A0A136L0F9_9CHLR Putative glycosyltransferase OS=Chloroflexi bacterium OLB14 GN=UZ14_CFX002000801 PE=3 SV=1 -SKPQNILVPARGGPHADLAMRVGLGLNRSGVSLLHIRKAGDP--INVAFKGLERVVQQMPEVEKQFE-VTNEAANLIIEKSK--QADLIVLGTTAQPMSSSASLGYVADQVLREANATVIAVKRA ->tr|G8QZW2|G8QZW2_OWEHD Universal stress protein UspA-like protein OS=Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL B-23963 / UST20020801) GN=Oweho_0540 PE=4 SV=1 ---MKVISALIDFTETSKKAVQYAAWIAKHEGAKVNLVHIEASKS--DNQEEIENRLIDFSGiedqnVPYTVSLGDGNYLKKIPTLLQRNQADFVVIGTHGVKGIFQTLFGANVLILVQSLGISALVVQDH ->tr|I3YRQ8|I3YRQ8_AEQSU Universal stress protein UspA-like protein OS=Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3) GN=Aeqs --IPLKMAFATDYNEFYQlSKLKPITRLVRQYNSQLHIIHVGLEANLDEKQQQNFEKFKNDLTEydtAFHFVPKNGNISKSLHAFIDEREIDLFTLIYHKHAFIKQLFREPVVSRVGKHAHVPTLVIP-- ->tr|Q26DI6|Q26DI6_FLABB Uncharacterized protein OS=Flavobacteria bacterium (strain BBFL7) GN=BBFL7_00758 PE=4 SV=1 --SPKSIAYATDFKKDDQlQNVTFLKMIIKEHNSKLQLVHFHKQSDIQNDVESQFSHLKSHLNDvefVTHWISSEDSIESNLKQFCETQHIDLVTLMYHKYSFLKGLVKTSTVEKLSFHTDLPLLIFP-- ->tr|A0A0F9IMW3|A0A0F9IMW3_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_1559740 PE=4 SV=1 --PISQIVYITSFLHNLKkDRLKTLKSIASNYKASLCILHIDNGTVMNTIQERNKEFLSTYLEAtklSFKTVPCDSSKVKTLVQFAKRHKVDLLVMYYHPHLFFDELFREPVLLDLSLYTEIPLLILP-- ->tr|R2PQU8|R2PQU8_9ENTE Uncharacterized protein OS=Enterococcus asini ATCC 700915 GN=UAS_01831 PE=4 SV=1 ----MNILVTLDSLHDSGAYLEKSFKLIQKLqGKQVLLLDVVDTAELEtieavaatfdeelvaskkvALADLVKELQGRYPALAITGSIKTGNPKSCIVKAAKDSQADLVISGSHHYSNVEYlLYHGSVSAYLAKHLPCDLFIIKNP ->tr|A0A0D2VG88|A0A0D2VG88_GOSRA Uncharacterized protein OS=Gossypium raimondii GN=B456_011G001800 PE=4 SV=1 -AGNGLVAVAIDKDKGSQNALRWAVEHLLSRGQAVVLIHVTKPTYETsslaptkytmdrqtkELFLSFHCFCTRKDIQCLDIILEDTDVVKALTEYVSHAAIEKLVLGAASRSGFMRKFRADIPSCVTKAAPdfCTVYTI--- ->tr|R0I8I6|R0I8I6_9BRAS Uncharacterized protein OS=Capsella rubella GN=CARUB_v10016139mg PE=4 SV=1 -VAVKGLIGDKL-GgAGSRRAVRWAVDNLLPKad--RFVLVHVIPTITSIptptgerlpveeveervvemyvrdvkkgfeKVFVPFLKMCKSTSV-tksttILRKHFSDSYPNQVLTVWLWDHSLQTYSPGKNYiARCLDRr-TRGPgVPLTVLKYVPgtCEVYIV--- ->tr|M0TMW9|M0TMW9_MUSAM Uncharacterized protein OS=Musa acuminata subsp. malaccensis PE=4 SV=1 -RPPASTAVAIDKDKNSQQAVKWAIDHLLLGSYAVILIHVKTKPPLNrrypspfgcscvrtyettsdaireqaenemsQLFLPFRGFCARKGVHMTEVVLEDNDVSKAIIDYINTNYIQNIVVGASSRNALTKKFRNPdVPTNIGKLAPefCAVYVI--- ->tr|A0A178U8X4|A0A178U8X4_ARATH Uncharacterized protein OS=Arabidopsis thaliana GN=AXX17_At5g61050 PE=4 SV=1 -DGALIVAVAIKGNnSKTKGVVRWALQEFASQeHVVFKLLHVQPRDSN-svsttrkdlttsvykkdvdrktrEMLLPSRDMFVHREV-qLDIMVLESDDIADAISKAVQDHGISELVIGASSsIIF-SWk-LKRSnLSSRIADATPrfCSVHVI--- ->tr|A2XBG2|A2XBG2_ORYSI Putative uncharacterized protein OS=Oryza sativa subsp. indica GN=OsI_09613 PE=4 SV=1 -APPLTVGLALT-DsKSSTYALQWALSRFKFTkdddAPIFLLIHVLTKLLTVptpmgnhipidkvrtdvadayfkdvhhqaqQMLLLYKNMCHQNKV-kAQVLLIKGNDVSQTVSTVVSDYQIKILIVGVTAr----TRk-PFGNrTSSKICKNVPsfCTAYLV--- ->tr|A0A1J7I7M9|A0A1J7I7M9_LUPAN Uncharacterized protein OS=Lupinus angustifolius GN=TanjilG_32960 PE=4 SV=1 -GVNGLVAVAIDKEKGSQNALKWTIDHLLNRSSTVFLIHVKLKPGSLstspslfgqrsgmqigdegpvgktdpdalnkNIFLPYRVFCTRKDIQCKDVLLEDVDVSKALIEYVSNAGIEHLVLGSSTKAGLFKKFKVLdIPGIVSKGAPdfCTVYVV--- ->tr|A0A066ZAC1|A0A066ZAC1_9ACTN Uncharacterized protein OS=Kitasatospora cheerisanensis KCTC 2395 GN=KCH_10170 PE=3 SV=1 -SPEPEVAVGFDALEPADAVLEFAFEEAQLRGARVRVVHGWELPPTYGyagwipveserqelgalavgmVSDAVAPWREKYPRTLVLEDVRTGGGAAALVEASA--QSDLVVVGRRSRTLNLGPKLGSVAHAVIHHAQAPVAVVPHD ->tr|F0T9L5|F0T9L5_METLA UspA domain-containing protein OS=Methanobacterium lacus (strain AL-21) GN=Metbo_0511 PE=4 SV=1 --MFQKILVPINPIEDQDLLVKTAYNLGIERDSEVKFVYFGDDPKAISQLEFYIEKCTQKGLNAsyyfEKFVGTKEEIPEKIAKISE--EYDLVIMGHLKYDKIYRFVHQSTASDLINLVTIPVMIIPDS ->tr|A0A0S3PKE6|A0A0S3PKE6_9NOSO Putative chloride channel protein OS=Nostoc sp. NIES-3756 GN=NOS3756_52310 PE=4 SV=1 -LQFNRWLVPMAGGPNARIAIKLLPALVTLGnEPQIRLTRVFKPLdfqPDMTVLEQAIRQLMRRRqlSSTVIAApVQADSVVEGVIKLVKTEGYDVVVLGASREGLLQQAIQGNIPEAIASGIDSTVILVRGA ->tr|A0A086CIK4|A0A086CIK4_9CHRO Chloride channel protein EriC OS=Candidatus Atelocyanobacterium thalassa isolate SIO64986 GN=ucyna2_00076 PE=4 SV=1 --KCNNWLIPISYESNAKQILKLLSELIQLYssqnPPKITLCYTFSLNskrLAHKLLEKKAKLLAKKLNCEIFPIfTRSRSTLKTVFELSSTKTYKVIVLGINQKELSNYVVQQKISKLINQHNNSTIVIIKES ->tr|K9YCG4|K9YCG4_HALP7 Cl-channel voltage-gated family protein OS=Halothece sp. (strain PCC 7418) GN=PCC7418_1597 PE=4 SV=1 --ASQRWLIPLAVEqTNIKPLMSLLPQLSAVGnAPEYLFCTINATEkenPFQ----GTVQQLSKQLQAPVQSLtLPTPTTENQVLQLATEKECDVIVLLttfkaTSPSFSLDTSFENNFPAIVAKRFSGTVILIRPA ->tr|Q8KPT6|Q8KPT6_SYNE7 Putative chloride channel protein OS=Synechococcus elongatus (strain PCC 7942) GN=SED0022 PE=4 SV=1 -LPLRHWLIPLSAQVPQTGLAEPLEQILQLItDPDISLCQIDLPRqtVSANRLQQLQRRLENRLRQPIQADlICARSVTAVLLDVMQSRGIEAVMLSMTLEQLPTTTLWK----DLLAQAPQTVIIQRR- ->tr|A0A075FHV8|A0A075FHV8_9ARCH Cl-channel voltage-gated family protein (TC.CIC) OS=uncultured marine thaumarchaeote AD1000_100_C06 GN=TC.CIC PE=4 SV=1 -------VLSTVGLDQEQTAVAHAtGELFRQSsgakDATLKVIAVESE-----------------------------KTSKIIEQFSQRDHsaDELAILALSRQNFLALIKNAEVRELL--KCQVPIIFSVGQ ->tr|K9SWU9|K9SWU9_9SYNE Chloride channel protein EriC OS=Synechococcus sp. PCC 7502 GN=Syn7502_02411 PE=4 SV=1 --LSHRWLIVVADCSSPDRAFNLLPHLIAS-DAQVHLCHIFHKPnfeEGL----INPQNLARKLKNPIESTaVCAKSIADAVVDIAKQENSDVIVLITKPHEI----------KQIADAVDCRLIFIGCG ->tr|A0A218PXP5|A0A218PXP5_9CYAN Cl-channel voltage-gated family protein OS=Nodularia sp. NIES-3585 GN=NIES3585_04030 PE=4 SV=1 -PHSPLP------TPHSPLPIPHSPIQPLAShNGWRT------------------------------------------------------------------------------------------ ->tr|A0A1Y0MS94|A0A1Y0MS94_9FLAO Uncharacterized protein OS=Gilvibacter sp. SZ-19 GN=BTO09_09050 PE=3 SV=1 ---MRKILIATDFSKNAAHAAQYAARCFANESVHYHLVYVSDCHSKPgrkppklpckgekcasnriklQQFNVNFQKHLDPKRHRADVHFLDLPPVEALRKMVLKHDIELIVIGCC--SEEKQPQLGRFAQDVIIRVQCPFLIVPP- ->tr|A0A0L0M1W3|A0A0L0M1W3_9BURK Uncharacterized protein OS=Candidatus Paraburkholderia kirkii GN=BPUN_1703 PE=4 SV=1 --MYKHILVAV-GPGFSESALDTAISRALECNARLTALHVVDQVPWWavvtadcnraqtlaviddharAVTRHSARLIERAGIDGTVRSIElppNASLGETIAKASMALGADLIVLGGEADTGWRHG-GQRLRDAVCARTKCDVLIASP- ->tr|A0A137XH88|A0A137XH88_OCHAN Uncharacterized protein OS=Ochrobactrum anthropi GN=AYJ56_17935 PE=3 SV=1 -SNPRKIMIAWKDSKQSRKALQDAIPWLSQADA-VRLVRIGSPQLLE--IDWAVNQLKEVGV-NCDTVnaplLVDETVGTQLIKEAQKMKADWIVMGAYKYGQTLERLFGGVTETLLSHSPVPLFMAR-- ->tr|A0A0L6JRN1|A0A0L6JRN1_9FIRM UspA domain-containing protein OS=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 GN=Bccel_3619 PE=4 SV=1 -MMYKKILIPIDGKKPSEDIVDFICSIQGVTDLEITIIYVIEVPRSLPlhaelpdkvesaryAIATANEIAARHGVNIDTSIIYSRTAEDSILMTAEDIKADVIAIAQDNQ---KLRIFSNMASSIYQRAKCSVWLFNS- ->tr|A0A0D9WGU1|A0A0D9WGU1_9ORYZ Uncharacterized protein OS=Leersia perrieri PE=4 SV=1 --GRKRVMVVVDQSSGSKHAMMWALTHVASKGDFLTLLHVIPHAGagtggdasAAALANSLGSLCKAcKPEVEVEALVIQGPKLGTVLSQVKKLEASVLVLSQCKPSPFCCFMRSsgeEFVEECINSADCLTLAVR-- ->tr|A0A0Q4B9L4|A0A0Q4B9L4_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_00690 PE=4 SV=1 ----KTIIVPWDSSQGCEYALEHAFQLAQAVGDNVMILQLVKRPGMLltrakrsefeqqlaeqrQQLEREAQRLNMEFAEKRAAIIqnlktktaaagrefqevtitsmvlDYRSLVRSLNELVLTLSVNLFVTSQYYQLSRTTrLDLLPILRkmKSSKVDTTPFIIVNKP ->tr|A0A1F3JS14|A0A1F3JS14_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWF2_40_13 GN=A2W88_12260 PE=4 SV=1 ----DMIIIPWDYTESCELALLHGIQIAKEVNNHIMLARFLESPGFFtgksvkeriiteekEKLRVVGQRIMEQHQINPFVTVELGFSRNHFFKLIRDANANLVISGKTYKVTDKIqFKPKDIVNR-LRGLDIPFIVCQEK ->tr|U5E8J1|U5E8J1_NOCAS Usp family protein OS=Nocardia asteroides NBRC 15531 GN=NCAST_32_08940 PE=3 SV=1 -------VVDP-ASSGPGDALAAAVRAAYERATDVVVIELARPVV---raspengadVEATITELRRRFPTVRISVLSYFGHARTALEKFGG--TAQLIVVPRDP-QALRPFLHGM-ARTALWHTRCAVTVVPPS ->tr|A0A0J8UHU3|A0A0J8UHU3_9MYCO Uncharacterized protein OS=Mycobacterium heckeshornense GN=BMW24_14685 PE=3 SV=1 -------IVA---EADNGGVLRRAFDEARLRAAPLRVIASWRAEAPD-dvgdesrlvqahLTRRVAAWRRRYPDVDVEPVAVRGSICRYLAENAE--SIQLFVSGSHS-RVCELGRADNAGCSVLTVHHDHL------ ->tr|A0A1V4PQI6|A0A1V4PQI6_9MYCO Uncharacterized protein OS=Mycobacterium sp. AT1 GN=B1790_16935 PE=3 SV=1 -------VMAVHGGPDDDRIVDYALNEARLRRAPVLAVDV--------shngdyasdaadLRHRVSRWQEHHPSVHVYPVHAPATIAGFLSQQdDL--RVQLAVLGSAD-VRHVVTILGSDRETGRPTSGCSVLVVR-- ->tr|A0A0F2PH26|A0A0F2PH26_9FIRM Universal stress protein OS=Peptococcaceae bacterium BRH_c8a GN=VR67_03890 PE=4 SV=1 --MEKQILFISDGSASATKAGAIAIELAATRQSDLRAVFILDEGWGSllgdewintsdtrmkffswfegelktraeQVLNQFSNQAVSSGVK-VETAILTGKTEKVIAEAANNERTVLLVLPNPNSTEPaAAAGLRFNLHHLAKKVTCPILLGPQ- ->tr|F4L4B8|F4L4B8_HALH1 UspA domain-containing protein OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_3939 PE=4 SV=1 --PIKSVVYATDFDVANLASIEKMVAWCQALDANLYLVHVNDDPADNAWAKQQMEKImraleEDNEDQRVRFTILEGdDIMDHLEHYMQEVKADLIALTAYRKGFWDRILRSGLAHEVIQEVNIPVLIFKS- ->tr|W2UDX1|W2UDX1_9GAMM Universal stress protein E OS=Gammaproteobacteria bacterium MOLA455 GN=uspE_2 PE=4 SV=1 -----------NHRLLGERVLQKASELATALNIELHVVSVVPDWSQTqaivgpmpgmpgqfptviadmgaqaleHAEDVIRETLVKLAIDSDVIEVRRGFADIELADAVG--DSGALVIGSAAARKLTAkvadKLFGNTSEKVIHHVRGDVLVVH-- ->tr|A0A0S8JE77|A0A0S8JE77_9BACT Uncharacterized protein (Fragment) OS=bacterium SM23_57 GN=AMJ86_07110 PE=4 SV=1 -----RILIVANGSLPGKDVLMFSKQFVQSASEPPTLLTVLNPWMDHppcqnNGITNFAHEDKKYPY--LHSKTVIGQPVEGVIREIKECGYDLVFVGVQGNPLLRRIFHSSSAMRIAELAPCPVVVVKG- ->tr|A0A0N9YTF0|A0A0N9YTF0_9ARCH Putative amino acid permease YhdG OS=Thaumarchaeota archaeon MY3 GN=yhdG_1 PE=4 SV=1 --IRKNMVILYDDGDNSNEILRVTDYFANSGNFNLIVVA-LNRNTkmINEKKTEFNNTAERkeyksdYLARKEYFKqagvdfneiyvSGE------IEKDA--MQFGKLLLESvlvynPDliitessLGKYSLLSKSKFANLLIYQVRCPVIVVKDV ->tr|A0A151AA93|A0A151AA93_9EURY Putative fructoselysine transporter OS=Halalkalicoccus paucihalophilus GN=HAPAU_36010 PE=4 SV=1 ---PRNILLPTVGGPHAAFIENIATAFTDDERVSLTLLYVDENDTdaVESLLLDRQTALQGsgVNAS-----iaSISATNvSEAIIQFAEAGEYDTIMMGItr--GRILQRSEIGHIAEDVGEQFSGEVLLGKYY ->tr|A0A0T5ZFI7|A0A0T5ZFI7_9ARCH Amino acid permease OS=Thaumarchaeota archaeon CSP1-1 GN=XU09_C0005G0047 PE=4 SV=1 --ELQNIVVSYDKGRHSNLGLEMANSLSKSLNSNIRIVRGIVES--PEEERDILGIINEkmfdLDMKKIPVErvypktdnaMQS------LLQNFDSGKPEMIIVGAGNqsdqafsPKTMEVVEKSS----------NTVFVIRDS ->tr|V6ARK1|V6ARK1_9ARCH Putative amino acid permease OS=Thaumarchaeota archaeon N4 GN=NITUZ_30058 PE=4 SV=1 --DFQNIVVSYDKGRHSNLGLRIANSISKSFGSKIRVVRGVVES--PEDELEVMNAINEmmfdLEMKNVQFEkvypktknvAPS------LLEVFDKVESEIIILGAGNqadsafsPKTLEVLSRTK----------KSVMVIRDH ->tr|A0A0S8B0K7|A0A0S8B0K7_9BACT Uncharacterized protein OS=Gemmatimonas sp. SG8_28 GN=AMS20_08270 PE=4 SV=1 --GPRGVVLPTTKGANAELAAELVPAFGSWFDVPVRAVTVIPSEVpqHEADqfIAEAQETLTTagfpGELKVVRRR---DVV-TGLAQ--LLRVRDLVVMGAp--sTAPIAALFGDTVPAALARRGQHPVVVVRDV ->tr|A0A075WM74|A0A075WM74_ARCFL Amino acid transporter OS=Archaeoglobus fulgidus DSM 8774 GN=AFULGI_00018630 PE=4 SV=1 --EFRDVLISTIGGPHAKLGYEIARALVEDKSGRIKLLYVGSSEKerEKAEkvFEEAMEILNGLNVERE---FAISSSpSDVVAR--EAESFDLVIVGAse--RTFLKNFLTGLFPEKVVMKTSKTVAMTRKW ->tr|I0A231|I0A231_FERFK Cationic amino acid transporter (Cat-1) OS=Fervidicoccus fontis (strain DSM 19380 / JCM 18336 / VKM B-2539 / Kam940) GN=FFONT_1 ---SKKIIA----------------ILSEDEKYIVDEVKEIFPDReiEEIIiekepnTNNISKTLNE------------------VLS--KESDTAIILMSFniwe-KltkyKWTMKKL---IFPYFVFKRGSFSIDVLRQ- ->tr|A0A1F8YIL6|A0A1F8YIL6_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium GWC2_65_14 GN=A2X88_08585 PE=4 SV=1 ---VKRILLAVEDTLSCRLAINIAPALSEELKSPVTILRTIDPDAgkAEEQgvAAWMEDVIKDlpfrvpVEKQVIRSH---KVA-KTILE--NVRETDLLLMGAsr--hVGAISSLFGTDVTEAVVEKAGVPVLLLKRY ->tr|A0A1J4WK74|A0A1J4WK74_9BACT Uncharacterized protein OS=Parcubacteria group bacterium CG1_02_39_15 GN=AUJ31_01070 PE=4 SV=1 ---LKTILLPCAPGPHLRILGQTAKVIAEAFDSKIKAVFVTTKREaeKSDPEEKLNQCVSAmeipsqipLKTQVLYAEq-SSPRDiAYQIVQ--ESQNHGCILIASar--TRLFHEMIFGNVPEVVTRNSTCSLIMVKSQ ->tr|A0A1G2PKG9|A0A1G2PKG9_9BACT Uncharacterized protein OS=Candidatus Terrybacteria bacterium RIFCSPHIGHO2_01_FULL_48_17 GN=A2806_03865 PE=4 SV=1 --KRVLVCIPPEGGRHLRYVGRVANSLAGTFGGTINVVGVISPGLpeQQHVaqEQNMLRNIARmrlkvpASVH-----LLRHLSpSQAILE--IEEDFDVIVMGAar--ERFFAEMRAGSVASRVARETQKTAIIVKGH ->tr|A0A1Q7NXL1|A0A1Q7NXL1_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon 13_1_40CM_2_39_13_2 GN=AUI61_03835 PE=4 SV=1 --EISNLVVSYDKGRHSDLGLEIAHSFSNTLGSKIRIIRGVVES--PEEERDILSRINEkmfdLDLRKVPVErvyttsldiTKD------LLQNLN-QKPEIVIVGAGNqadqafsPKTIEIVEKSL----------YSVFVVRNS ->tr|M0GAP3|M0GAP3_HALPT Cationic amino acid transporter OS=Haloferax prahovense (strain DSM 18310 / JCM 13924 / TL6) GN=C457_11301 PE=4 SV=1 ---PGRVLVPTAGGANSELADLFAVAYAATGADVTLFHVVTDGDVdtAESFLADKQESLAEseIDVD-----taVQEGEDiAKTILQYARSEGFESVIIGAag--EGILRRVLFGEVPETVGEEFDGEVVMVRKH ->tr|A0A151AAQ8|A0A151AAQ8_9EURY Universal stress protein family protein OS=Halalkalicoccus paucihalophilus GN=HAPAU_30600 PE=4 SV=1 --MGNSILVPINSIPPTIAALNHVLTLE--GSHEITVLQVCPiierddsirqtvipeaideqreasGQTAEQVFSKATDYAAEHDV-TLETVIDSGHPAERISAYAATNDITRIVIGTQEQSLLSRILRGSLPNAIMKRSSVPVTTI--- ->tr|I7M3S2|I7M3S2_TETTS Universal stress family protein OS=Tetrahymena thermophila (strain SB210) GN=TTHERM_00459310 PE=4 SV=1 --EFKNLLVAVDGSDYSRKAYEQSLEFLEQKKDQFDQLIIAHITNrnkkylpekmqaetiYDQYKLECDEKFAHNKYKLVFEEKNPNQPScrEQIISLCGQLQISFLFLGFYGRKGVKEqrG-LTQTVSQACYHSKVPLVIVK-- ->tr|A0A0G4G4H5|A0A0G4G4H5_9ALVE Uncharacterized protein OS=Chromera velia CCMP2878 GN=Cvel_543 PE=4 SV=1 -----SFLVCVDASKASVKALQAAMTLSRSKDDKIVIVHLAALDQEslhqdcrkEAVEKKYQAIMVAHmsDMPNVELKIMENTPdmslSRHIVDLIEQDgSFDFVCVGADQMKSRLSdksldnedtWHVGSVSDHVIKHSPCTVVVARN- ->tr|A0A1F3B377|A0A1F3B377_9PROT Uncharacterized protein OS=Alphaproteobacteria bacterium RIFOXYD12_FULL_60_8 GN=A2516_00215 PE=4 SV=1 -SGIKSILVHLAPDQDHMARLRAGYNLCKRFNAHMSVLAINTHPHLPsgsegrvaslsfleqerevaaeknkAMESELDQWRQESEIT-YDWRQAEGDHLEALVEESL--YHDLAIVSQSEPSSLEDMLFVGLPDHLPLLAACPVIVLP-- ->tr|A0A1E7IR31|A0A1E7IR31_9DELT Uncharacterized protein OS=Desulfuromonadales bacterium C00003107 GN=BA869_04910 PE=4 SV=1 ---YEQVLVLLDASDTAESVGKYSVQIAHLCGADMYLLVLEEVPGE---LIDGIRKLGEKGNVHIIEKWVEGNPMIEAVKEVKSGNYGLTVLSWKGTGVIRA----DMIKKIVNDAPCSVLTV--- ->tr|A0A0Q4B8L6|A0A0Q4B8L6_9BACE Uncharacterized protein OS=Candidatus Bacteroides periocalifornicus GN=AL399_02070 PE=4 SV=1 -----TILVPTEFTPECDYALELAVLLAERSSASLTVLHIPEPGEDTAGAQQQLAHFTHEvpNDLPLRVLTVPGEVAETIARVAVDESAEFIVLGSEQVGDPEGQ-KQSETLRIFRYGTVPFIVV--- ->tr|A0A1D2R636|A0A1D2R636_9EURY Uncharacterized protein OS=Candidatus Altiarchaeales archaeon WOR_SM1_86-2 GN=A7316_06470 PE=4 SV=1 -MIVNTIICATKGSEGCKLAENKAIEIAKKNNSKLVFLYVIDIKFMEKssgggewteddvtsglkniggvILDLASEKAVEAGMSqdNVLIEEREGDIASQIKKSVDENNADLVIVGHPAtdmgfleRHLLRRDGMENFINQLKEKIGCEIMIV--- ->tr|A0A181ZDK1|A0A181ZDK1_9MICO Universal stress protein family protein OS=Curtobacterium sp. 9128 GN=GA0004736_2397 PE=4 SV=1 --QWTSVTLAADAAHPHDEAVRWIAARAGTGIRQVRVVGVDPalegrvGTDGKRVAEHVADETRSAlPGVDVEVVRHAGPAAAALLTESD--TTDLLVIGTFRSRRGST--VGGEAARVAGRAAVPTVVVPDG ->tr|A0A0F9J9G4|A0A0F9J9G4_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=LCGC14_1481290 PE=4 SV=1 ---PKEIALASDFKKsYDASVLLSVRTMANLCGAALRIVHIDEEEKLDDHQKFNLDSLLTFFGPlahSVERIPNFISKTKIIQLFLEKSDIDMLCMVGYEHGLLEKMLREPVIENMVLKIDIPFFIVPE- ->tr|L0DJT2|L0DJT2_SINAD Amino acid transporter OS=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) GN=Sinac_4719 PE=4 -KPKMHIMVPTQGNT---RLIEFAIEECKSRQAELQILFIrhlavtpmgpttiptlAEDEQALQLFERLRTQAHDSGVPLRLLYGVARDIPDAILDMAVTHGANMLLLGLTRRGALWKAMKGDVIQGVAEHLP--------- ->tr|A0A1G3ZK49|A0A1G3ZK49_9BACT Universal stress protein UspA OS=Verrucomicrobia bacterium RIFCSPHIGHO2_12_FULL_41_10 GN=A3F67_06995 PE=4 SV=1 -HHGGPILAAVRGLG---KTLEFAVSEAKETGRPLYVMFVreqlviapgdrkrkwHDDPEAKNIFDTLKEE--GLGDSILPCYAVSDSPPDTIADLASTVGAERVIIGASQRGTLVNMLRGDMVTKLSKLIP--------- ->tr|A0A1J4VRC8|A0A1J4VRC8_9BACT Uncharacterized protein OS=Candidatus Omnitrophica bacterium CG1_02_46_14 GN=AUJ72_04095 PE=4 SV=1 -LYKGSTLVALKTVS---AS---LVEQAVLYvkgktENVIYSLFVeemppgwaypeavEPSKEAIKVLKRAVQEFEKRGITSVPLWSFGDNAGALIVKTAKVLNLGTVMIGTTKRGPVERLLKSQVLKTISDQLP--------- ->tr|A0A1M3CQG7|A0A1M3CQG7_9CHLA Uncharacterized protein OS=Chlamydiales bacterium 38-26 GN=BGO14_04630 PE=4 SV=1 -ATNKSWMVAITGLS---KSLEYALEESQIHQIPLYILFIreqkvvtesdhqknwLDDPEACKVFDYIIAR--EPRMPMEFVYTITAHTAHSVSEIAQEKKVSHIILGRARKASlsFLHVVRGTTVRDLARLIP--------- ->tr|A0A023D1H9|A0A023D1H9_ACIMT Uncharacterized protein OS=Acidomonas methanolica NBRC 104435 GN=Amme_005_008 PE=4 SV=1 -------VIGWRPSAALDKTIAAAMKLL--ETADHVTFLIGDESHEETALPDFARTLEAKGVAvaVTRFQVESGQLGEQIREHALAANADLLIMGSYPRRHFLEWLFGPPTQDMFTRTTLPIL----- ->tr|A0A0R3NCH3|A0A0R3NCH3_9BRAD Uncharacterized protein OS=Bradyrhizobium retamae GN=CQ13_14715 PE=3 SV=1 --VIRDIVVNLVTSNSRDPAAAYAISVARMFDAQLAGIAMCHSPAIvaggmeavpadlieslheesvraaNGAIERFKQAAAQAHLPAeaQMVETSIEGIPRTFGRIAR--TFDLAIVAQAEPEVT--TSTGLAAEAAMFESGRPIVVVPS- ->tr|E0TFD8|E0TFD8_PARBH Universal stress protein family protein OS=Parvularcula bermudensis (strain ATCC BAA-594 / HTCC2503 / KCTC 12087) GN=PB2503_074 --AIGTVIVPAFDPKGVQQAVSAALPFVESQGAHLVGLHLREryPASqVpeynwhaavlkefeagvaaraDEIRHAFEVAKGSAD---ATWLQPEGSEGLDFGPALR--AADLIVVPSPKCCDR--PDAAGLIEDILIGSGRPVLLAPG- ->tr|A0A1B1UTK0|A0A1B1UTK0_9BRAD Uncharacterized protein OS=Bradyrhizobium icense GN=LMTR13_34315 PE=3 SV=1 --MIKDIVVNLATGNSRDPTTAYAISVARMFDAQIAGIAMCHSPAIvaggmeavpadvieslreesaraaNGAIERFKQAAAQAHLPAeaQMVEASIGGTPRIFGHIAR--TFDLAIVAQTQPEAV--TSTDVAAEAAMFESGRPIVVVPS- ->tr|A0A219B3J9|A0A219B3J9_9SPHN Uncharacterized protein OS=Pacificimonas flava GN=B5C34_02240 PE=3 SV=1 ---MRRIIVHAFDDAGFETRMEAAMAFARTYDADLTIMHIRPdfTS--vgepyaaglftgaafaeaeerlkaDERK--FREVADRL-LKGedvtYDWEIRSGLPEREFAREGV--LGDLLMLSPLKDDFSGQA-GDTFVGRMLANATCPVFMAVS- ->tr|E1SMW8|E1SMW8_FERBD UspA domain protein OS=Ferrimonas balearica (strain DSM 9799 / CCM 4581 / PAT) GN=Fbal_2435 PE=4 SV=1 -----------------AKVVRTAMTLSKRLKGQLTLVHSCYTPSFmikyramiqSTHQRVIHDFLAKHHLQRLNWHLLLGEPADTLSDYCRTHQSDLLVMGLVARGLIKKRITGSTTDQLMSERACDLYLIP-- ->tr|A0A126S4U4|A0A126S4U4_PSEPU Universal stress protein family 5 OS=Pseudomonas putida GN=AWT69_002500 PE=4 SV=1 -GQYRHLLVLLTEVDPHSAALRRGLALAQLSGASVHVLGLFTPNQqhllreerlnvaditrqyehYRVQLKGLIERYHGSAIALTVDSLNAEDVRSQAIDYISELRPDMVIKDSEALSAWGRLFGIPLDCALMRGFKGVSQFVPTA ->tr|A0A1H0I0V9|A0A1H0I0V9_9PSED Universal stress protein E OS=Pseudomonas reinekei GN=BVK86_07325 PE=4 SV=1 -RPLRLLFLAPFSQAAHCPGLEYAGDLARALGVPLHIAAFTDLHGaesagpagaecpdvvrqsvlalRQKWLKDESARLQEKGVDVHPEIVRASSSATEFAACAQRLEADLIIKDMQARPGQAHCGLSPQDWEFLSVSPVSVLYVQPG ->tr|G2HX61|G2HX61_9PROT Putative uncharacterized protein OS=Arcobacter sp. L GN=ABLL_1839 PE=4 SV=1 -PEYKNILIPTDLSKSSKKNIEYLVNLF--PEANFHIEHYYKTFFEDrvklygfdedeihdfvdfyatEAEHDLNKFINNLDipkdI-KLFTKAKKFiDIKTMVDESIEYKTIDLLSLSVGSSLSIFSF-------DLLEHSTKDVIIYK-- ->tr|A0A099U6Y7|A0A099U6Y7_9HELI Uncharacterized protein OS=Helicobacter apodemus GN=LS72_07235 PE=3 SV=1 -PDYINAFSPTDFSNNSLKLAKVTKKLF--DNIKITFYHMINRPFEIrlghygaddeqiskynksaeeKAKEQSKKFLKELDKNNVNMVLDSGiLTYTRLLSVAESKNSSLVVLPTSGKVSFFAL-------DVLEHSNLDVLICK-- ->tr|C5ZYG2|C5ZYG2_9HELI Putative uncharacterized protein OS=Helicobacter canadensis MIT 98-5491 GN=HCAN_1475 PE=3 SV=1 -PDYTNIFSPTDFSEASSKIAKITKKFF--PTAHLIFYHMISRPFEIrlghygandeqisnfnqtlenKTKELAKKFLKNFPEHKNEVVLDSGiLSYTRLLSVAENKNASLIALPTSGKVSFFAL-------DVLENSKIDVFIWK-- ->tr|A0A1Q9UHQ6|A0A1Q9UHQ6_9NOCA Uncharacterized protein OS=Rhodococcus sp. CUA-806 GN=BJF84_07570 PE=4 SV=1 ----GRFVVVIDGSPTDTDQVKWAVGLAQRAQAHLEIVHASSVTEWSaamaasletsdypsRIRNAAQQRLEEAvqsaheldPGIEVDSKIVELSAAKMAESISA--DATLLILAADKSGPLRDIAFGHSATTVINAASCPTLVWRR- ->tr|A0A0A5I952|A0A0A5I952_9VIBR Uncharacterized protein OS=Vibrio tubiashii GN=NM22_12210 PE=4 SV=1 -----------------KAIINKSLDIGSRINASTTLIYCQYVAPYlhhyandilTHQKIAINDFLKLSKYSQLPLRLIRANPEEGLPMAVEAVEPAILALGACKRTALSRYWFGSTVDVLMAKPPCDLLLI--- ->tr|A0A061PJI7|A0A061PJI7_9VIBR Uncharacterized protein OS=Vibrio sp. JCM 19053 GN=JCM19053_1549 PE=4 SV=1 -----------------KAIVSRGSKLEQTLSGKMTLVYCRYVAPYlsryraeilSNQKAGITDFISAQKLTRVPLLLPEGNPETALPKAVKQSQAAILIMGACKRSMSSQFGLAAL------------------ ->tr|A0A0A6QSU5|A0A0A6QSU5_9VIBR Uncharacterized protein OS=Vibrio caribbeanicus GN=NM09_05300 PE=4 SV=1 -----------------KAIIDRSLETGAKLNASTTLVYCQYVAPYlnrysqeilANQKHAIKEFLNNNKFYQLPLRLIKANPEEGLPDAVDAIGASILAMGACKRIALSRYWSGSTVDVLLANPPCDLMLV--- ->tr|A0A0C2MYR4|A0A0C2MYR4_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_15253 PE=4 SV=1 --PKRTIIIGVNKEEGSKRALEFYLnVMCDVELDHVYLCHFYEPPplpffsikhplniPWQDWERALRERVETVNKfmnecqwlcerkrVSCTTFTSFTSPHKGLMELAKEVNASMIVIGKKS-NLLEEILGKNVSSYVAHHCHIPVTLV--- ->tr|A0A0C2MI60|A0A0C2MI60_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_15252 PE=4 SV=1 --SRRIVMIAVNKKPESKKVIQLYLdNMCDKDHDLVYLCHIYKAPslstyplsslksiPWQKWEKKLSQRINEINTfmneyqcmcdvkrVPSLVYITYGKRKKGLLELSKILKASMIFMGKKR-GFFSKFFGG-LPVGVAHNCRIPITIV--- ->tr|V6ATI9|V6ATI9_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon N4 GN=NITUZ_40011 PE=4 SV=1 -TMFKHILVVFVGPKIKAKSFLVGLGIAKKFNSNIFAVDCVYKHPPRfhffetkadkesvakqkakslESLKKLQTFANNANVQVTTKLVLTDAITDWVTDYVKSNRIDLLIMDYPHEPQYDIDLSADIIRAILEKVSVPVLSLRD- ->tr|A0A0D5C417|A0A0D5C417_9ARCH Uncharacterized protein OS=Candidatus Nitrosopumilus adriaticus GN=NADRNF5_1768 PE=4 SV=1 -KIFKNIAVAIITPTHTKKSFDVGLELAKKIGSDLTIIECMYKIQPKlyffetksdkkvaqqqisklkAELEKWKKIAKEQGINVKTKFALTDSISHWVIDYVKVNKIDLLIVDYPKLSMVEMSMYDDIINTIHHESHCHLLTTKP- ->tr|A0A0D8FVB1|A0A0D8FVB1_9ACTN Universal stress protein family protein OS=Ferrimicrobium acidiphilum DSM 19497 GN=FEAC_13910 PE=4 SV=1 -----HLLVPVGSTQDDSAALFWAAaDLANRLELQVTILHCREWDLAKgvkyfmetkdeatSIITSAMKWFSALNIPaqGVLCDVERGSIGKAIATTSTDYHIDSVMVGLRHKRRLLPGLMGSTVTQVERLVNCPVIVIK-- ->tr|A0A133VR25|A0A133VR25_9EURY Uncharacterized protein OS=candidate divison MSBL1 archaeon SCGC-AAA382M17 GN=AKJ55_00305 PE=4 SV=1 --NLENLLVPVRHPDDVNRVTELASLLLD--RGRITFLTVVEKGSFpssqknwrisSDAIERHSRKFKNRWVEIVPRIRYSDSVWEGVLEQAEIDDSDLILIGWGGKITFRS-LRQTPMERIFANSDRDVIAFKSR ->tr|A0A1Z9BLU9|A0A1Z9BLU9_9BACT Uncharacterized protein OS=Rhodothermaceae bacterium TMED105 GN=CBC65_03370 PE=4 SV=1 ----STVWIVVDFSDTTEPALDMGFRLARAMGASVKLTHIVKPPYEFsgrkesqleagkegarhtlSVIKEDYAAREPYQHIPIELHLEEGSTVATVLSLVKSDPTSLLVLGFEVDESGPRGLFGNITNQLLVESPVPVIAISSN ->tr|A0A1F7N2C1|A0A1F7N2C1_9BACT Uncharacterized protein OS=Candidatus Rokubacteria bacterium RIFCSPHIGHO2_02_FULL_73_26 GN=A3D33_00355 PE=4 SV=1 ------VVVAVDGARGGRTALALTLAFPWPAGTRVTSVTARRTAATRgrppyvlaavergvRRVAARARRALAQRWPDAAAVLVDREPVPGILAEARRLRAAAIVVGWHSHSAFRRLLMGDVARGVVRGAPCAVLVAK-- ->tr|A0A1M4U5Q8|A0A1M4U5Q8_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Psychroflexus salarius GN=SAMN05444278_102193 PE=4 SV=1 ----MNVLLLTDFSSTANHVMKYASILLRDKPAKITLMHVKKPCSgdscsgkcntiFESKLNKDLKVFKDQNNPlhQLNTHFIEGQYLDSIRDFVKRQDIDLIIVGNSHQHQIEDeIDLDKKTVDVITKVNCPVLLVS-- ->tr|A0A0J5QYD3|A0A0J5QYD3_9BACI Uncharacterized protein OS=Bacillus pseudalcaliphilus GN=AB990_13640 PE=4 SV=1 -RNHEKVLVFLEFDMYSPTTILRGAKVAKAFECDFEVLFLHEAE-NTyhdgpeVELmnTESKKLSEDLGAKHFQIKEFPTYnKAfKHLVSYIKEGGFTQIVLTHVAESRFEEMLHGSFPNLLMKEMP--------- ->tr|A0A061N2C7|A0A061N2C7_9BACL Osmosensitive K+ channel histidine kinase KdpD OS=Geomicrobium sp. JCM 19055 GN=JCM19055_1807 PE=4 SV=1 -PKENHTLVCVQHGKNGLRFIEQALQTIDHTLHHTTIFLFDNMACEEdeahriVGMSLFQKLALKYEADLL-ISEGKPLTNrKLIAETAKEVQATHLIVGQSIESLWRKWIGKSTIDHLSKDIP--------- ->tr|A0A061NSB9|A0A061NSB9_9BACL Osmosensitive K+ channel histidine kinase KdpD OS=Geomicrobium sp. JCM 19037 GN=JCM19037_4007 PE=4 SV=1 --MTEHTMICVKHGQNGLGFIQEALTHIED-EHRLTIYLFDNMACEEdhehriVGMSLFQKLAEKHSADLL-ISDGRALTTaKRLAETAKEIGATHIIIGEYSEGLWRKFLGRSTADHLTDHLP--------- ->tr|A0A0F4SD49|A0A0F4SD49_9GAMM Uncharacterized protein OS=Pseudoalteromonas sp. S2292 GN=TW82_04610 PE=3 SV=1 -MDKKKLLVLIDSVNCAKTALLHAKQKALQDSKHIDIVAFSYEDTGnilfslspeqvlaiqdkqlsllRATLEPLLKKELTD-CEYTFQTVWHESPEQWLNNEINATNYDMAIKTRHIDAQT---QFSELDWQLIRFSPIPLYLA--- ->tr|A0A0S3AUY5|A0A0S3AUY5_9GAMM Uncharacterized protein OS=Pseudoalteromonas issachenkonii GN=PI2015_1758 PE=3 SV=1 -MDKKKLLVLIDSVEFAKTSLQHAKQKALQGNKHIDIVAFSFEETGnilfslspeqllslqdkclsslRAQLEPLISAELEG-CSYTFQTAWHEAPEQWLNEDINTDDYEMVIKTRHIDSDS---QFSELDWQLIRFTPIALYLA--- ->tr|K6X0G2|K6X0G2_9ALTE Uncharacterized protein OS=Paraglaciecola agarilytica NO2 GN=GAGA_2360 PE=3 SV=1 -MNVSHILVIADRKESLQKAVGHGAILASQFNASVHVAGFCYERLSiladntpkqeldnakqkiiqtsQAWLDETVAESSLP-SSTTDEMVWSKDIAGWVTQHCADHQYDLIIKTGHRSEHA---FYVPTDWHLLRNGSAPLLLV--- ->tr|A4A3Q5|A4A3Q5_9GAMM Universal stress protein UspA OS=Congregibacter litoralis KT71 GN=KT71_16701 PE=3 SV=2 ---MSKILIVADKGK-SCVATSRGLELAAKLGYDVEIVAFVYAPLNridggkteqaelkqqildkrRAQMLERIDAFAKKEQKVALKVVWLKTVHPWIVKRTTNGNFAAVVKTTHATGSL---GYTSTDWHVLRECPLPVLMV--- ->tr|B7RUG6|B7RUG6_9GAMM Universal stress protein family protein OS=marine gamma proteobacterium HTCC2148 GN=GPB2148_3506 PE=4 SV=1 ---MSKLLVIADVKG-DGIATPRGLELANKLGLNAEVYAFVYAPLSrlkvtaaekavikkrllaerEAEVGSRISKFSRDDQKVKLKVLWEKDVADWVSKKCSKSNYQMVVKTGSQTESF---AHASADWQLLRECPAPVVIV--- ->tr|D1CB38|D1CB38_THET1 UspA domain protein OS=Thermobaculum terrenum (strain ATCC BAA-798 / YNP1) GN=Tter_1087 PE=4 SV=1 ----MKALVPITGQEEEEQIIEMLRSLPK-SIEELIVLHVQDPSPektfemlelghhhiskyrleevqktqeayAQQAVNRAIDTIRRYVNILATGIILKGRANEEIMRAIQKEGAELVILFAKK-NASGPKSIGKTARFVLDHAPCSVLLIR-- ->tr|A0A0D6YIB7|A0A0D6YIB7_MASLA Universal stress family protein OS=Mastigocladus laminosus UU774 GN=SP67_12755 PE=4 SV=1 -----NFIVGYNSSPNSHTALDISLLMAHQTrlatnsHVLVQAVYVLEEYYTndffdisptqefqtsesfeqfstycpinlpsknvqtpvltqtnkfaqaERILWQARCLAEEWQSY-FKAHLRFGCVADELKKVVASEAATILFLGCKSAKHP-------IVQKLGSNFPCSVVGIPTC ->tr|A0A1Q4RDM2|A0A1Q4RDM2_9CYAN Uncharacterized protein OS=Calothrix sp. HK-06 GN=NIES2101_36560 PE=4 SV=1 -----KFIVGYNSSRQSHTALDIALCMAHQArlasnmQITVQAVYVVEDNQScyiqetyssihqpvyadivstsvltearlkseclmimeqtDAILCQARSLAEEWQVD-FDCLLRFGCAASELKQIVELEGADVLFLGCNSVKHP-------IIKSFGADLQCTILGIPSS ->tr|A0A1Z4QPH5|A0A1Z4QPH5_9NOST Uncharacterized protein OS=Cylindrospermum sp. NIES-4074 GN=NIES4074_46240 PE=4 SV=1 -----NLIVAYDASPNSHTALDIAFWIAHQTrlatnaQVSVQAAYVLEDNPRklysdifsveqdplplecsvsdvsksvtlvltqpkltavatnlpgesltpikqaDRILWQARSLAEEWQGT-FKSHLRFGCISTELKKVVESEAADILFVGCKSADHP-------MIEKLGANFPCAVVGIPSC ->tr|A0A1F3XYJ6|A0A1F3XYJ6_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 GN=A2603_13585 PE=4 SV=1 -RKFNSVLVPMSGEIRTSHALTLGIKLASEFAVPLDLIYVVDPETvseecpcpllsflddayheYPRMLEELIAEASpltsiEEKASIRDFHFCTGEAAREIVNQMKKRHTSLVAIEWHGRLTRGHA---RVLKHILRQAHCLILLVKTE ->tr|A0A1F3Q5G3|A0A1F3Q5G3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFCSPLOWO2_12_FULL_35_15 GN=A3F72_05235 PE=4 SV=1 ------ILTALDFSKCSDNALNYALKSYNDYNAKIIFLHAIQSGYIETNIEKLVDKdpkitkhnienklqtiiskkiKKYKSKCDYEIITEFSLPLDLILKTLHKVKPFFILLGSKKTISFVQNFFKNDTIKIIEQAKCPVIVIPEG ->tr|A0A1Y0GZE1|A0A1Y0GZE1_9BACT Uncharacterized protein OS=Armatimonadetes bacterium Uphvl-Ar1 GN=CCB80_08300 PE=4 SV=1 ----MRILVGIDTMQAWQGAANLLVRLFPD-GFEAELVHCIESLLPDssfpsvsldhpiatiyqefrrqgqEALDLATAFLSQHNVQ-CHQSIREGNVRNVFTEIAEKSNCDLIAIRSSIKSPSESLIFGSTAKALVLSANIPLLIVKNE ->tr|A0A099Q1T2|A0A099Q1T2_9XANT Uncharacterized protein OS=Xanthomonas sp. Nyagatare GN=NC00_07525 PE=4 SV=1 ---PTHLIFATNFSETCHAAIPTVAQLVDRLRARLTILHVHAKGKRAQARQSLDAFFAEAsNYPGCERALASGPAAAGIVSFCRSRDDALLIMPPSERTGLPRPLHVSLRARVLERVATPMLTLP-- ->tr|A0A0Q5GH87|A0A0Q5GH87_9XANT Uncharacterized protein OS=Xanthomonas sp. Leaf131 GN=ASF73_07840 PE=4 SV=1 ---PTHLIFATNFSETCHAAIPTVAQLVDRLRARLTILHVHAKGKRAQAQQSLDSFFAEAsNYPSCERSLSSGPAAAGIVSFCRSRNDALLIMPPSERTGLPRPLHVSLRARVLQRVATPMLTLP-- ->tr|A0A1G3Q770|A0A1G3Q770_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_49_6 GN=A2014_11450 PE=4 SV=1 ---MQKIYIPICGATEAKRAIQKGIETAKRFDLEVVVINVVDQESInklqrykifideesamftdslkrdaEKYLHYAEKIAEQTGI-AVTKVLLEGDPFSEILEYIKNDSADikLVCIAKRRESQDCRDLFGVVERKLLSQTDFDLIV---- ->tr|W5WY28|W5WY28_BDEBC Putative universal stress protein OS=Bdellovibrio bacteriovorus W GN=BDW_04870 PE=4 SV=1 ---LKTMLFASDFERTTTKDIEHILSICKSLKANLVVFHHANisykepsqesspkSSAYRRKVNEMKSWIEITSKKskvscEVLVKSDFKSVTEHIKSIVKTKKCDLIFVRAKA-SAKKTLMGGSITRAVVRESTLPVYILKN- ->tr|A0A0S2HRI5|A0A0S2HRI5_STRVZ Universal stress protein UspA-related nucleotide-binding protein OS=Streptomyces venezuelae GN=AQF52_6940 PE=4 SV=1 ---MRGTM--ICGTPRRIGTVSFG------RQLPTSARPSYPESyeTETiamvpvftvsldgwakRLVHQEQTHLKELvPGLANAGNPVADDARNAPQRVAS--ESEQTVLGSLGLTPAVS----SASPAVVARAARPEVLVRGE ->tr|A0A0U5J571|A0A0U5J571_9GAMM UspA domain protein OS=Thiocapsa sp. KS1 GN=THIOKS11770032 PE=4 SV=1 ---PRRLLIPVTERPDGFRSGMPFLRLFAPQVTRLHIILIARVGRRRflrmshegaerllgpgqayceRVEKEIVEQLGLGPEVMDAQVVVSDQVAREILIAAHRTKSRLVYLGVSERHPAERFLYGDPVEQVLRDASCDVAIYRG- ->tr|A0A1B9ZBL7|A0A1B9ZBL7_9BRAD Uncharacterized protein OS=Bradyrhizobium paxllaeri GN=LMTR21_11820 PE=4 SV=1 ----MRLLAVVDSTESTNRIVDFITAFSEgRAATEAVVLNVQSKRLDARlrgyqnfkkdeiderlinefafpILNSVTGRLEKAGIL-CSSKAEIGDPVTTILRCAAENACNVILVGAQPSKGFDSWlpntmrvwLRSDLALRLIALAPASIVVVK-- ->tr|A0A1G1FV62|A0A1G1FV62_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWD2_57_9 GN=A2010_10945 PE=4 SV=1 ----MKILTLYDGTMQSKAALRYGLRKVREKGGSLTVLQVFQTDLFVDydagpraqdiaraesarHRRDAEAIISAAGNEgiSVNVRSEEGEPVEEAARVAESEQPDLVLASPRYKA-------------LVRRTSRPVYIIPGT ->tr|A0A0F9XLD2|A0A0F9XLD2_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0202220 PE=4 SV=1 -QAIRDIAVHVDGSDGDAAKTSHADMIATMFDAPLIALLMNYLQAAPippgpgrswlnaelrkrgveqgdAAEIRARERLAGLRA-PSEIRRIDYAYQelgARIGPPAR--SVDLVVVGRPHG---DGGQWPEMFEAVIFDAGAPAYVVPPN ->tr|A0A0F9UIU0|A0A0F9UIU0_9ZZZZ Uncharacterized protein OS=marine sediment metagenome GN=LCGC14_0216880 PE=4 SV=1 -HGIADLAVHLDGGNQDAAKIAHLQTIRAIFGAHAEAFFANPIPTAFipigpgyeglpaeiwaegaaagdVAEKTIRARLDKLDF-AVELRRVDGMPHelaPATATLAR--SLDLFLLGRPNG---DR-WLADILEAVLFDAGAAALVIPPD ->tr|A0A165Q8D8|A0A165Q8D8_9RHOB Universal stress protein family protein OS=Pseudovibrio sp. W74 GN=PsW74_03445 PE=3 SV=1 -MSIK-TVVTLTDTSGDQVASRVAVELSKLTDAYLIGVVPNYEtSYYLctagpmppdyelrlqeqsaatlnKSLEGFAKHFDGAGI-DGETRVTDITLGgtfDELMHLGR--LSDVTVIRQDDPA-KPEPMRAAMIEAMVFDTGVATLIVPHA ->tr|A0A1B1AH29|A0A1B1AH29_9CAUL Uncharacterized protein OS=Caulobacteraceae bacterium OTSz_A_272 GN=ATE48_07915 PE=3 SV=1 -MVWRDILVFADGSQEGLSRVALAHNLAHRREAHLEARLITLAPEPPlgetsfaveravaalrqaaheraMSAVRAVEEMEKPGQ-RFSVYHDECSWGevaHLGAAAAL--TSDLAIVAQPREG-RDGDLDRRILEAALFRAGTPCLIAPPW ->tr|A0A0R2VI64|A0A0R2VI64_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium BACL12 MAG-120813-bin55 GN=ABR95_09185 PE=3 SV=1 --PFQKIIFPFECTAKDLDIIQFCIKLAEIFHSTIYLIHFLLEGAVInkTILDKINTRFHKEiSEERLQIHILADkNITGGISKFAERVSADTVVMVTHNRGLMATLFHMSTTRKMVLYNNTPLLAFKAE ->tr|A0A1Q3W9B1|A0A1Q3W9B1_9BACT Uncharacterized protein OS=Spirosoma sp. 48-14 GN=BGO59_25445 PE=4 SV=1 --PLRTIVYASDYLPGDIDNLQKLVPIAQAFNSNITVIHITRDESDEavKTLADFEQQVNAEvGPSNIRFRLVKGtSVEKTLEQYLDENKVDLLVMSAHQRSLPEKLFGKSMTRIMTLYSHISLMIFHQK ->tr|A0A1Q4F3Y2|A0A1Q4F3Y2_9SPHI Uncharacterized protein OS=Sphingobacteriales bacterium 44-15 GN=BGP14_16920 PE=4 SV=1 -RMPAKVVLTTDLKEVKeKISSSSIFKFLDAIQAKLLVVNVARKDKDVSHLRTEIMDLHSllDRYTPEIHYINHPDTIEAIDEFAQHHQAGIVITFHEQQNRPAALFHKSVSKKLAWHSRLPLLVIP-- ->tr|A0A1V3MSD1|A0A1V3MSD1_9SPHI Uncharacterized protein OS=Sphingobacterium sp. CZ-UAM GN=BWD42_24440 PE=3 SV=1 -RIPRKMLIATNLKEVKlKLDRLLINAAEVLRKSEVYVVHVTKEDPASKAVRTEINLMNEllASYHPIYSYILHSDIAIGINQYINENHIDMMVTFHRDKGLLSRIFNTSIAQKMAWKSQAAMMVIP-- ->tr|A0A1G1FV62|A0A1G1FV62_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWD2_57_9 GN=A2010_10945 PE=4 SV=1 ---PGTILVPVDSSETVKADRDMICAEARETGSAVLFLGVVPVHLYSsaerdeleqvrkktaSVIKSVQKWLGEQGI-KASEVFRAGYPDEEILKAAEEFSVSLIMLPAGGKTPSELAKAAAILLDEPERVKRPVYLMPA- ->tr|A0A1G1FDT1|A0A1G1FDT1_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_57_13 GN=A2X56_05655 PE=4 SV=1 ---PGTILIPVDNACAAPGTVEYVAREAIATASEVVVLGIVPVHIYSssekkelaavkkrtaDCVRRTKKLIHERGI-PVTDAIRAGFPDEEILKAADIHDASLIILPAGSAVPSELSKAASVLLDEPHRLRRTLFLVPA- ->tr|I0INM1|I0INM1_LEPFC Putative osmosensitive K+ channel signal transduction histidine kinase, sensor subunit OS=Leptospirillum ferrooxidans (strain C ---YERITVLVSeHTPSLERLVGYAGNLSRRMGGELLVLHLRKISflgkrspPDQEILSRFQQEARGAGGKFSILW---tRNPGWTLWRFIQRTKTTRLVMGHAGTQSP---WRKSLVRSVLRYFSrIDVEIH--- ->tr|E6PCU7|E6PCU7_9ZZZZ Putative Potassium-transporting P-type ATPase D chain OS=mine drainage metagenome GN=CARN1_2168 PE=4 SV=1 ---AERVSTavtFVPAIPSAQAYVERSAAVADALDLALEVRPLGDAD-----IADLNDAARRNNAELLSEPIDPaT------IDLE-RVRASLLI-----------VPRGAFARRIVNHALeRDVFVI--- ->tr|A0A0C2A3G0|A0A0C2A3G0_9DELT Universal stress protein UspA OS=Enhygromyxa salina GN=DB30_02346 PE=3 SV=1 ------MIVPYDFSAHARRACALAMQGFPfGMDAQIEMLHVIDADLYAnvlahkhvpdddaidsylaDELTRIHAELAVAHAKhstpprllEPKRVIVRGRPHASIDARLHEPDVIGGLLGGQGHGGATEKLLGRTAQRVIRHASVPLLVVKR- ->tr|W5Y4M6|W5Y4M6_9CORY Uncharacterized protein OS=Corynebacterium vitaeruminis DSM 20294 GN=B843_12195 PE=4 SV=1 --PVSRITCMYDPQHGDFQLFRYALERAIEMGVELRVVTLDVGDDIKgspgahpdaanslRRLGIDVDGLVRGGH--LSFLKATGQNTPRAIAELTWREGEVTMIGSTREAADGRVSAGPFATKLISYIPTPIVMATA- ->tr|A0A0B8YKB4|A0A0B8YKB4_9SPHI Uncharacterized protein OS=Pedobacter glucosidilyticus GN=PBAC_04690 PE=4 SV=1 ---IKNILVPTNLTVGSLSVVQYALHQFKGYAFNITLLHVLPLPDAisdllmlsrksdenehiPAEFHAAVQRLTLLfplRISSIQIEHQYGLSASILSQIITSKEIDLIL---HCKTVFKSAAnsDEQKLLKLLDESAYPVLYVPE- ->tr|A0A1M6V3V6|A0A1M6V3V6_9BACT Universal stress protein family protein OS=Hymenobacter psychrotolerans DSM 18569 GN=SAMN02746009_01489 PE=4 SV=1 ---MKRIVIPTDLSLYSVHLIRYALNLLQGQTCHITLLQLTPLPDSitdlltlprpdraplerNPEFGKAIARLQRHyalEIEAIQVAHLYYDGAQQLKQYLQELSIDLVL---APVPLTRPAKGAAHLHRLLTNAPCPVLYIPE- ->tr|A0A0Q5W5W4|A0A0Q5W5W4_9ACTN Uncharacterized protein OS=Modestobacter sp. Leaf380 GN=ASG41_17495 PE=4 SV=1 -RPRPWILVVVEETDADHGALVWALREAARREATVVAVRVLDDAAdgplldgltlpagdahTAALDDAVLRAVVETGIQgRTRTAVLDPHVFAALTGAAR--GADLVLMGGRGKTLLRR------------------------ ->tr|A0A0G4H4U6|A0A0G4H4U6_VITBC Uncharacterized protein OS=Vitrella brassicaformis (strain CCMP3155) GN=Vbra_10573 PE=4 SV=1 -----TFFVGVDGSEASHQAVDLVMKYSMpKSKNRMVVAHVYDESKTYlprpmqqaVLLAEMENRLitsfpaARYELK-WTAKRPEHGIKEELVHSANETMADFVVVGFYGRkgRKV-DHSIGSSADYSMRNASASSIVVKDT ->tr|A0A098SAQ1|A0A098SAQ1_9BACT Uncharacterized protein OS=Phaeodactylibacter xiamenensis GN=IX84_10050 PE=4 SV=1 --QPKRIAVSLGSRLNLNLMVRLAGALATQFGGTVTFLNILPKDFTAAQQAEsGKIFIEAIQRHSARAlyntqVMASDNPIDTLVEKSG--EFDILIVGTTKVGFLQRMVVGNFTTQLTERAHCSVAIVR-- ->tr|A0A098LIS7|A0A098LIS7_9BACT Uncharacterized protein OS=Sporocytophaga myxococcoides GN=MYP_3588 PE=3 SV=1 -RPLKTIVYACAISVRDHNNINELSEYAKEFDAEIIILNVRDklEQEYPEIAAVMLDEIMDHvHYKNIKLITKTGTNVSAIIKkFIDEIDTDLVVMATHHRNFLEAILSGSTTEKVLNISSHPMLIFH-- ->tr|A0A1F4EZL4|A0A1F4EZL4_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_12_FULL_67_28 GN=A3F77_05940 PE=4 SV=1 -NAMLRVLIPVDASRNCQFAVKHVISQFMNNTAmEIHLLNVRPPFSShiarfvsrkarhdyhrdegEKALAPVRQMLNNFGI-PHAAHIELGDKAKIITDAARRLRCDQIVMSTARKNSLTRLVESSVTNRVLELTTVPVEVIAGD ->tr|W7QJR7|W7QJR7_9FLAO Uncharacterized protein OS=Cellulophaga geojensis KL-A GN=KLA_10533 PE=4 SV=1 -----KILVLSDLKKTTVSTVKSTVNLAKMINGDVSFFHVKKASDVvvrdnqlsamraineqynstDRIISAIIKPISKVQNIKIKYSFSFGNVKNEIAKQIEEQQPDIIVLGKRK-PKMINVIGDHVTDFVLKNYKGVIMIAAND ->tr|A0A0F7PBM0|A0A0F7PBM0_9EURY Uncharacterized protein OS=Halanaeroarchaeum sulfurireducens GN=HLASA_1055 PE=4 SV=1 ---MGTIFVAYGGPGNKNAVLEFAVEQAAASEHDLLVYHVLEDEQEsSQEIREEVERVVESVDPSVTYEVqfntrsevsdrtnisKQKRLTSAIQESDR--DYEYVVMGCVERPTIEGIVHASMTEAVLEMHSTPVMLVP-- ->tr|M1WY31|M1WY31_DESPC Uncharacterized protein OS=Desulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) GN=BN4_20026 PE=4 SV=1 -MDMLKALVPVEMTLASNVALRYLCQKSDLLGIGVQPIHIEEPDHKrhssqtgwirkswesglrQAGLEEVRRILKSEKLDcfvLPNPIIRVGSREDKILEELRLGWYDLFVEGELA-NFNTGEFRKRLRSRFYKQMPCPVLIVRN- ->tr|A0A239JW64|A0A239JW64_9BACT Nucleotide-binding universal stress protein, UspA family OS=Pontibacter ummariensis GN=SAMN06296052_12421 PE=4 SV=1 -KGLKSVVFAADLAKSPAVAvLDSLRDYLKAFRSTLQVLYLYSKDQQQAEQEKSLAALEDmgKAFSDLDYRVtfqQREDTAEAIKQFIQEQQADLLVLAPQKRGFLEDLLNKSVTQRMMAKTFIPLLALPPL ->tr|A0A142HM76|A0A142HM76_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PAMC 26640 GN=A0256_00405 PE=3 SV=1 -KEIKHVLYASDLTDYESE-LAKVVAFARPIHASVDLMHISYPFEFAFDKELMEATLKKKADYDVTIVKRQRDITNALLEdiddAIKVSKPSLLVLFTHQsRSMFEKLFYPSNAEEYSFYGKIPLLTFN-- ->tr|A0A0B8YEI5|A0A0B8YEI5_9SPHI Universal stress protein family protein OS=Pedobacter glucosidilyticus GN=PBAC_10000 PE=3 SV=1 -RDIESVLYASDLINLDKE-LDQVIDFAKPIDAKIEVVHFGFPSDIAKKVKLAEEKVKNHSDYPVEFHVQPSDFIKSLVNnietAVKRSKPSMLVMFTDQkISFFKKMLFSGNTEEFALNTRVPLLVYP-- ->tr|A0A1G3J2N3|A0A1G3J2N3_9BACT Uncharacterized protein OS=Sphingobacteriia bacterium RIFOXYC2_FULL_35_18 GN=A2472_04910 PE=4 SV=1 -KAIKKITYVSDFENLVTE-LSKVTKLNSLLKGQTEALHYARMGVNHPDTLKKIKIFSKANYIGIKPNVLETNIEYSLVDrltkYIGKQHPDLIILFTRQkKGFFEQLFLPSKAAELTFSTKIPTLIYP-- ->tr|C4FLJ6|C4FLJ6_9AQUI Uncharacterized protein OS=Sulfurihydrogenibium yellowstonense SS-5 GN=SULYE_1450 PE=4 SV=1 --EITKIFINFQFNNISLKALEIAKDLANKYNSQLIIFHEIEDVYMMkkiaasfglpvppdleeknktSAKSRIEDLLTNFSNDVKIIVDISESVKNSLPKFIKEESPDLVII---------------------------------- ->tr|A7I3R2|A7I3R2_CAMHC Universal stress protein family OS=Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 / CH001A) GN=CHAB381_163 ----MKVVVCIKNNQICDNVRDYGIYVAKILKSQISFVAIMENQELgdsfyglaaggivlgekdmilsnyqnleqenneetlkkiQEYLDKCVKKANLEGLKAEQT-LKKGDFIDIISTYKN--EADMFITAARYD---ESDDIDFNANMLIKELKVPVLLVNKE ->tr|A0A0A8H016|A0A0A8H016_9PROT Putative universal stress protein UspA OS=Campylobacter insulaenigrae NCTC 12927 GN=CINS_0260 PE=3 SV=1 ----QKILVCIDILEPCKNSVDYGIYFAKKLNLPLMFLYVVESNFTntelacsfgigssgcviedlveeqtqknenlckesKKILKELSLYAKDKGVAECFGVQRDGDLEEILKDYDG--KMRLVIAGLKGNG--EKQKIGKHIEELVRALNVPILLINSA ->tr|A0A161SI63|A0A161SI63_9NEIS Uncharacterized protein OS=Crenobacter luteus GN=AVW16_08365 PE=3 SV=1 --MLKNLLLVLDAGPIAEQARELALSLAQTHGAGLTALSLIDTAPLHageaapaggsaflearnakweaewlegarERIVHMREAAAAAGVTVSSVLAEDDQPDVALLNQAR--MHDLVVASSDCHLGAESrPHDTHWLSRYLADAPRPLLLLTPA ->tr|E6VEH0|E6VEH0_RHOPX UspA domain protein OS=Rhodopseudomonas palustris (strain DX-1) GN=Rpdx1_2411 PE=3 SV=1 --MLKRTLILLGQTESSVSARDYAFRLAQRTGTDLAGLAGLDLRSIEtpmlggigtsaykaqleqelksqaeatrQRLHEEFERECRERALPFEWLSFEGDPIEAFQLATE--TRDLVVAGHDTGYGGDLtEPLSEILAKLLLRSPRPLIVCPDR ->tr|A0A0M9UDA6|A0A0M9UDA6_9CHLR Glucosyl-3-phosphoglycerate synthase OS=Ardenticatena maritima GN=ARMA_2221 PE=4 SV=1 --EVKNILVPIRGSKESALLIETALALTEALNSRITLLFAEESQSEErdEAIWQEIERSTRGHRLVTRRLRVIGDVVSAVRQIAG--EYDLIMVGVaEQRAGSGARRVGAIARGITEAVNTPIILVKTE ->tr|A0A1Q3SN51|A0A1Q3SN51_9CHLR Uncharacterized protein OS=Chloroflexi bacterium 54-19 GN=BGO39_26475 PE=4 SV=1 --PIKQILLPVRGGSYSTLALSLVSNLAEEWSAGITVMHNLGNNSGLadSFrpsQAQSFSAFSDGYEvedeslttlqalalelpPNAKLVAMQGKLIQGIVQEAH--HHDLIVVGAsETRERMDEQASGeKIAEKIARETRRPLLVVKTA ->tr|A0A0E0N3D3|A0A0E0N3D3_ORYRU Uncharacterized protein OS=Oryza rufipogon PE=4 SV=1 -SPHRRIAIAVDLSDESAYAVRWAVQNYLRPGDAVVLLHVRPTSVLYgadwgsipvsvsddadgevapaasaeelqkkreedfdaftsTKAEDLAQPLVDAQIPFKIHVVKDHDMKERLCLEAERLGLSAMIMGSRGFGASRKggkGRLGSVPTGRQQGqqMSCTLCLR--- ->tr|A3DKX5|A3DKX5_STAMF Uncharacterized protein OS=Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1) GN=Smar_0172 PE=4 SV=1 --NIKKILIPAIKNEIISFATEYGITLF--PDAVYHLVSVIPSMKRrslytrlyvgsfrkiaEDAFQDIEIVLNKHDCTAIKKAILKGNPVKEIRKYVKQYKIDLVIITSSATPTPPPKLIGSTATKIIGSLEIPILIITP- ->tr|N6V2C7|N6V2C7_9RHIZ Uncharacterized protein OS=Rhizobium freirei PRF 81 GN=RHSP_54571 PE=4 SV=1 -MNFRTILAPIGVNH-LEKDLRQAIVFSEAAQAHLSILVVAMAAPPPvggygefvsaawleeregdltklaDAVETAKASLSqsGLSYDVQDLYTEYAWAGEDIAPCAL--YADLVLVGAGAA--ADVQFSKRVIDGALFQSPTALLFNPTD ->tr|K0Q5Y1|K0Q5Y1_9RHIZ Putative universal stress protein OS=Rhizobium mesoamericanum STM3625 GN=BN77_p10193 PE=3 SV=1 -MSIKTVMCVFGVDR-WDQDVKSAIEFCETQGAHMTALVICMGSVPAiatyeaisttwlegqqkeidrlaDETKAVREILErtELSFDIQEIYTEFAWADDDIAQHAL--YADLVLVGAQAA--GNEDLQRRIVDGALFESPTPILINPRT ->tr|W8RPI4|W8RPI4_9RHOB Universal stress protein family protein OS=Roseibacterium elongatum DSM 19469 GN=roselon_00641 PE=3 SV=1 -MAYKSILTVLTDDKDVAPVLDAVAPFAAAAEAHLDVLCLGIDr-TQTgyyfagattlmhdetlaqaqaeatRIEQAARTHLAqsDISWGVEALVAQSASVTPVVARRAR--FADLVMLPKPYG--ADLpSDAPVMVESAMFQGNAPVIVLADE ->tr|A0A0Q7VAT4|A0A0Q7VAT4_9RHIZ Universal stress protein OS=Mesorhizobium sp. Root552 GN=ASD50_05125 PE=3 SV=1 -MTFKTILTVAGPESSCEGDLKLAADLCEQAEAHLSVLVMTLAAPPPigeyaavvsdswlqereadlkhlnARKAEISTFVAgsAVSGNVVSEYPEAGWAEEMVGRRAR--YADLTLAGPELL--KTETLKEKVIEGALFWSGKPLLLVPEG ->tr|H0HDV6|H0HDV6_RHIRD Uncharacterized protein OS=Agrobacterium tumefaciens 5A GN=AT5A_19281 PE=3 SV=1 -MSVKTILAVIGAHD-AAADISQAIDLARELDSHLSILVLGAALSPVtadypvttvwleerqneidelmKIRKEAENLCNinGVTYDVDQLYEDRFIIENNLCMRAM--CADIVVAGNGIR--KDIDLRKTVMAATIFDARSPLMFMATQ ->tr|A0A1M3A4J9|A0A1M3A4J9_9CAUL Uncharacterized protein OS=Brevundimonas sp. 67-6 GN=BGO02_16050 PE=4 SV=1 -MPWTSLIVYVDDEADNPARLTE--ACALAG--AHGARLIGvsaCAp-ETPvadaygagillgevmaaqqarnettlkSAEQRFRGAIEaaGVEGEWRGDVGDP---TGLTLRHLR--AADAALVGRDAG--GAsawraPhpadl----------AMRAGRPIVVLPPN ->tr|A0A1Q5PJB1|A0A1Q5PJB1_9ACTO Uncharacterized protein OS=Actinomyces sp. VUL4_2 GN=BSR29_08315 PE=4 SV=1 ----MSVVLGYFKNPESEQALQTAMALASQEQLKLHILAPTPNDNHeiEAENQALWEQVENTEI-EFEVHRVAGEAElsKQILALAQEQQARYIVMGIQS-AAAGAVQIGPNARQILLNASCPVVTVTAN ->tr|A0A1S3XTP0|A0A1S3XTP0_TOBAC uncharacterized protein LOC107768687 OS=Nicotiana tabacum GN=LOC107768687 PE=4 SV=1 -NSTRKVMVVADPTRESAAALQYALSHAVAENDMLILLHVGNPNAWrnllgsiikkplpnsatssfsstststtslpsqseegrgihnnpfgaffkkslasyasppsssmlsnvaedggvrgcggkgyMDFLGTMKHACEVAQPKikvCTETVEMDGNAkekASIILAKAASLGIDVLVIGQRRSLsnvILRPRRSVSlrglgldMAEYLIENSKCTCVAV--- ->tr|G7L828|G7L828_MEDTR Adenine nucleotide alpha hydrolase superfamily protein OS=Medicago truncatula GN=11426587 PE=4 SV=1 -NQSRKVMVVADPTRESAGALQYALCHAVMEQDELILLHVIEnTSSWrntlstflkmpslgtsttaslndiggggggggggggaaagggagggsaaegetvVDFLEEMKNACKAAQPKlkvRTMKVEIDN--gkdrANTILLHTLDQRVDVVVIGQKRTLsstLLGYKRPTgGslkgvkmfdTAEFLIQNTpgTCTCVAV--- ->tr|M0BEV4|M0BEV4_9EURY Formate/nitrite transporter OS=Halovivax asiaticus JCM 14624 GN=C479_11395 PE=4 SV=1 -----RVLVPISNPRTERDLVELACTLAGSReSGAVHVVHFVQAPEHgafhgdpeqhdrivdasERQLEAFEPMGEHHDIEFQTSTVVTPRSFEDVFDTANRLSPDLVLMGWGRDTVWSSARAERPLDELTNQLPTDFLIVRD- ->tr|A0A1H9YVX4|A0A1H9YVX4_9EURY Formate/nitrite transporter FocA, FNT family OS=Haloterrigena hispanica GN=SAMN04488694_101269 PE=4 SV=1 -----RVVVPIANPRTESTIVDLACTLASSHeNATVHAVHIVQMPGRasmrygagqtdrivsesEQRMETVRQRARSYDVDYETSTVVSHRSFEDVLHTAERERADLVVLGWGDDRPWGKGRAEGRIDELTSNLPCDFLILKD- ->tr|A0A088F480|A0A088F480_9SPHI Uncharacterized protein OS=Sphingobacterium sp. ML3W GN=KO02_18485 PE=3 SV=1 --KMQSILIPTDLSSNFSKVKNKVEDLLPTGSPfQVSIIKSFNIPSVFfpfiddqetkvkaeklimVQYEALKKKLKISDTWSFKAVYQNGkSISDIILRENKNCRADMLVMAAKGASTIATIFLGSTTNEIINRDPFQVLYI--- ->tr|A0A1M5GM13|A0A1M5GM13_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Flavobacterium segetis GN=SAMN05444396_10410 PE=3 SV=1 --SWDRILVPTDLSAMFRTIHAKMEVLKRINPPvNFRIVKSFNIPTVFfpyidiedqkvikeaekhinKQFIDAKKKYKISDDDVFVAVFRGKnSIVEIIKKESKAFNADLILMSAKGDSSVSSILIGSTINELINSAPFKAIYI--- ->tr|A0A0E0VS00|A0A0E0VS00_STAA5 KdpD OS=Staphylococcus aureus subsp. aureus 71193 GN=ST398NM01_2120 PE=4 SV=1 ----PHIAVAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFEISrqykdsQKQVHQHLMLAKSLGAK--VKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRNKRRDFFNKPLIDHLMSFEHsYNIEIVPIK ->tr|A7RSL4|A7RSL4_NEMVE Predicted protein OS=Nematostella vectensis GN=v1g240412 PE=4 SV=1 ----RTVAMPVDGSQRSKDAFIWFCKHIIQEGDHVLLIHVWFVPSFNHdrltwpaikgpyedwmydkrvaedsvdemldwYISCNKNVSKSINKIPLNHGADKKTQCEEICKAAKEHSADMMVMSHKGDTTNADpGVLGLTTDYCVCNAGIPVCVL--- ->tr|A0A1X7LQG3|A0A1X7LQG3_9BACL Nucleotide-binding universal stress protein, UspA family OS=Paenibacillus sp. 11 GN=SAMN06295960_3978 PE=4 SV=1 -MMSNKILAVIDSTSLSQQAIEIAFQVAQKKRTALDIVFCEHHHRSifnfgftmiaslsysgyvpidqyaaedllviqaedQDKLNQLQRDAVLAGI-DASIFRVEGSPSPVIAELTEQYSYKLIVIGDRRVQRNRKRLFKHVRRKMEQSPRCPILIM--- ->tr|A0A090WAU6|A0A090WAU6_9FLAO UspA protein OS=Algibacter lectus GN=JCM19300_4468 PE=4 SV=1 ----DNIVFLVDYKEDEIIPLGHVIEKSQEFNSKLHVIHFdlAHVESISPLMETFKQSLDLAHLNNVEFISIDSiNLKKSLTEYCINNKIDMVCLINHKRNFYQRLFSFSLTEDLLNNFDIPIMAIYRD ->tr|A0A0S8BSJ3|A0A0S8BSJ3_9DELT Uncharacterized protein OS=Myxococcales bacterium SG8_38 GN=AMJ62_13770 PE=4 SV=1 -NPMSTVLTVTDLTAASYQLVGLAASIAGPSDGQVILVSTYGGGGTSrrseppfaeranpewwrqqlearlrqegQLLERQRQWCADRGVRCRAELYEDGRWPELVLQSAQRSPVDLILVGMHQMSSPYQ-ISPDEVRRLAEAAPCPVSMVR-- ->tr|V4QMM8|V4QMM8_9CAUL Universal stress protein UspA OS=Asticcacaulis sp. YBE204 GN=AEYBE204_04005 PE=4 SV=1 -QSWARISIPVSGSASEEVSVGIAASVAEGFGAQLNFLFAPPDPAElapwlgegfmgtvqvaamdglksaaEEAEAIARETFDGLDYDGKVFLPLKSPVWQCLAVETR--LSDLVVFGDESARGRG--LLSEAFQQVLMEERAGVFIARQ- ->tr|I4YHF5|I4YHF5_WALMC Uncharacterized protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_62762 PE=4 SV=1 ----NKVLIGWKNSPDGNKALEHYLNKLAKPQDHVILLVVLPTTLFkssgfgtddkkmerkalrdlrehaQQLASEKIKLIEAKGA-TASLEIVHGERRYVIEWLALRRKVDLIILGRKKAHAPAKGLskvflghpIGSTVQHVLHKVSVPVLVVN-- ->tr|A0A1F8RBR7|A0A1F8RBR7_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_63_12 GN=A2W37_07805 PE=3 SV=1 -----SFLILTDGSASAQAALELGGQIARLAHARVTILGYGPTTDVlQRHLQEAKEKLGSGLAS-LEIRATLDLPHVAVAHEVERQVYDLAVLGFDASR---PPGGVALAENILRSGEHHLLLVSGT ->tr|A0A1Q6W979|A0A1Q6W979_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 13_2_20CM_66_19 GN=AUH10_13910 PE=4 SV=1 -----SFTACAVSAALAEAL-SRQPLLAELaarMHTRIA--------------PRVEPHLG----V-PDAPSATDEPSVGA---------------TAIAG---GSDCSRRAEWLLRRGAREVLVLPEQ ->tr|H2BY19|H2BY19_9FLAO UspA domain-containing protein OS=Gillisia limnaea DSM 15749 GN=Gilli_2607 PE=3 SV=1 -KGLEKILISMDYDQVlDPSEIEPLRKIISGSQIFVEFLQLKKDDFDELLWKDQSEKLNKTfSDLNFTFQTITGVHFvAAVSSMVQIQKPDLLLLHAEKEKFLDGIFYASNISSVINKIKIPVLILHP- ->tr|K4IW68|K4IW68_PSYTT Universal stress protein, UspA family OS=Psychroflexus torquis (strain ATCC 700755 / ACAM 623) GN=P700755_003030 PE=3 SV=1 -SRIKEILFSMQNEEElSFKGMDIFKDILTMHKCRLNVLELDDTRQTQASEKVDNQSIHKLfLDYPYTYFHLNTIPGlIALNTTTQLLKIDLHAVSIEKETFLKRLLFGSDTSQLAYGTHIPLLFLHK- ->tr|Q26DH5|Q26DH5_FLABB Uncharacterized protein OS=Flavobacteria bacterium (strain BBFL7) GN=BBFL7_00769 PE=3 SV=1 -HKPTAVQYVLDYDDVfKVCGKELFLEIVTKFASTINVIRFNHGFQLEPINYrEERESFINFcMPSPVIYELHKDQEPlKIIKKSLSSRNYQLQAISVKSQSFLERMISESHISEIVNAATLPLLVLRD- ->tr|A0A162F9S6|A0A162F9S6_9FLAO Uncharacterized protein OS=Aquimarina sp. RZW4-3-2 GN=AWE51_10270 PE=3 SV=1 -KELKTVLYTIDYNDYfNQDGIEPLLDTVQKHKASLRILKIKEDETVTIADFDDKKHMKEFfKGINHTFHSIINVPTaLAIASFIQIMNVDMTAMFIQRETFLDRFFNGSETSKISYGTRVPLLIMHT- ->tr|A8UL12|A8UL12_9FLAO Universal stress protein OS=Flavobacteriales bacterium ALC-1 GN=FBALC1_06638 PE=3 SV=1 -KKPKAVLLPLDSFDSlSGKAFSDALKFIKVNNSTLHILRINPNGIEPDTQSKDFEHIDFHlKDITNTYNVVNNVPMhFAVSSYIQTNAIDLSILIEQKESIFERFFMGSSTTKIGNHLKAPLLVFHS- ->tr|A6ENG3|A6ENG3_9BACT Universal stress protein OS=unidentified eubacterium SCB49 GN=SCB49_03624 PE=3 SV=1 -EGVNSALFSTHNCEDfSLEGVSVFKEMLNIHQAELNVLDIKDEGVVVNS-KENDTYLKRLfTDYPYSYFLINSMPGlIAVNTATQLLKVDLHAVFIEKETFLKRLLFGSNVSQLAYKTLVPLLFLHR- ->tr|A0A098LNG8|A0A098LNG8_9FLAO Putative universal stress protein UspA OS=Jejuia pallidilutea GN=JCM19538_3049 PE=3 SV=1 -KKPNDVLLPLDVPDStSGMAFTAIVEFTEKFCKTLHILRIQPYAKNSKEEKRDRAHLDTLKQTNYVYHKINNVPIpYVVACYSQTHNIDLIAIIAKRESLFDRFFSGSPTTQITHKIKVPLLVSHS- ->tr|A0A0D5YQX0|A0A0D5YQX0_9FLAO Uncharacterized protein OS=Muricauda lutaonensis GN=VC82_568 PE=3 SV=1 -QMPKKMIFANDLKKPiGTTALKVLKDLIKCHDIALTMVYFDRGNAMNEEQKANRKLYEDNfVGLKYRFEEVPLKTsIsSAMKSMlSQRNDVDMVIFKKNRHSFFEKLLREPIIRKVAFSAKIPLLILPD- ->tr|A0A090X525|A0A090X525_9FLAO Putative universal stress protein UspA OS=Algibacter lectus GN=JCM19274_3350 PE=3 SV=1 -TPIKELLLSVGPRDViDGNQFTDLLEFMETYQLHLNVLRLMPNKENLDIVKQDRSSLS---ILNCKYNVVNMVPIdYAVLGYLQTNTVDFMALFVRHEGFLEHLFSKGNTKINISKLPKPILVLHN- ->tr|A0A0C5CD30|A0A0C5CD30_9ARCH Uncharacterized protein OS=Candidatus Nitrosopumilus piranensis GN=NPIRD3C_1892 PE=4 SV=1 ---PKHIMVPFRPSDVFFRAFDEAVTIAKQNNARITVVKVIDYRAglgidmmmaadilsrecdlhkFDGILTGLQKQAILSDVNlDVKIMDLHLSPAKAFVDFAYQNDVDMMVMGCIKKKGLTKHFRSDISDEIMDLSPpCNVVLV--- ->tr|V4M6B6|V4M6B6_EUTSA Uncharacterized protein OS=Eutrema salsugineum GN=EUTSA_v10022572mg PE=4 SV=1 -----FVAVAVKgiigdklGGAGSRRAVRWAVDNLLPKAHRFVMIHVIPTIstiptptgerlpveeveerlvemyvrDVKQEFETVFVPFLKMCKSapcts---------pNAAATARGFLKDGAASFH-------N---------VQSKTLSDPRqsIE--AG--- ->tr|A0A0Q6CQ94|A0A0Q6CQ94_9RHIZ Universal stress protein UspA OS=Methylobacterium sp. Leaf456 GN=ASG52_19455 PE=3 SV=1 -TGVRDVMVAltEEGRG-deVASSLGYGLTLARDAGAHLTVESASIRFVTTglvlgnfvdelvgaenrrmaslarSTAERIAQDAARAGVVCTTESPSLQYdrLVARLSALAR--LHDLTILDAEPLAVLPD---RDVIEGLLFESGRPLIVVPPG ->tr|A0A0Q6ZFL4|A0A0Q6ZFL4_9BRAD Universal stress protein UspA OS=Afipia sp. Root123D2 GN=ASC80_10380 PE=3 SV=1 -MSFKDVLV-aLTTYPErtPNSSIEDAVQVAVALSARVSAIACEVRVPAPasplgtallnipamvaaelrksaanakDVLAGFQDAAERQNVLQDTILEKCSTanEPDVLVDYAR--LRDLTVVPMTNT-DGNE---RWYAETLIFDSGRPVIALPPE ->tr|A0A0B1Q5D1|A0A0B1Q5D1_9RHIZ Uncharacterized protein OS=Aureimonas altamirensis GN=LA66_11565 PE=3 SV=1 -PAYKTVMLTllPEADARnaASPATAMAIAITSHFEGRLTIDFL--SPQPAwipyslvtdmpgqmlaeqtrkleaqahASMDLAAGAARQAGIHPETQLISLDFlaLVGRAALRAQ--LQDVVVVDAGGSSLRDE---REIVEALLFRSGRPVIRVPAA ->tr|A0A090N6E7|A0A090N6E7_AFIFE Universal stress protein family protein OS=Afipia felis GN=BN961_00093 PE=4 SV=1 -MIIQDAML-vLKAYPTptSEEVIASGIQLAGSLNCRISAFVPETLIQVPgsflgnslinisgmaalemdkskrnaaTLIKLFRDLAERNGIQHEVIKERELAgrIPALTAEYAR--LKDLILLPVSQN-DLVD---QWDTETIIFNSARPVLLLPER ->tr|A0A1B2EYL1|A0A1B2EYL1_9RHIZ Universal stress protein UspA OS=Microvirga ossetica GN=BB934_43465 PE=4 SV=1 -QNIRSILIGitEEGDA-eeRSSALTYGLALARQANAHVTVQAASLKLTVThafisafaeglvaaenrrldglarAVADSSQRAAAASGLACTAQAPQLAYpdLIRSFSSLAR--AHDLTVLDAEPIALALD---RGLIEAVLTDSGRPLIVVPQG ->tr|A0A1G7QRD9|A0A1G7QRD9_RHOCA Universal stress protein family protein OS=Rhodobacter capsulatus GN=SAMN04244550_03262 PE=4 SV=1 -MADRIAYI-pLNTCPEgpSDAATLATIGLAGTLDCRMHVATFAVNIPPVasplggflinvkgmacaiedrskaecdRLRALIEAAARDS-SDV-TFVHHQPVmgAaLDWATTESR--YFDLALTPWSPD-SAST---QDMAQSLVFGTGLPVVLVPPS ->tr|A0A1W9KAZ3|A0A1W9KAZ3_9PROT Uncharacterized protein OS=Proteobacteria bacterium ST_bin15 GN=BVN31_11645 PE=4 SV=1 -KSFKPITNLtcMVRVYDepSRAALDQALAIAQHSKAHLIVMIAAAKVSVPfspagawfasplvgdlnhqtmtkakEVAQEVRAKAMAAGISADIQIMFDHVenVAEKAIKAAR--ISDLVVVDQSRGRLDTT---GILFEAALFHTGRPVIVASPR ->tr|A0A1W1YSM9|A0A1W1YSM9_9RHIZ Nucleotide-binding universal stress protein, UspA family OS=Rhizobium sp. RU36D GN=SAMN05880593_1014 PE=4 SV=1 -SRTRVCYV-pVVTYPDvvPDDAVLAAIDFARALPCRLHVTAFSVDVPHIasplgdllidipdmirtvevrsahdcrRIQELVVGRVEGL-VEA-EFS-IQPQsgYpGFAAAREAR--YFDLSLLPWAKG-ATSV---QQVAQTVVFESGRPAIIVPPG ->tr|A0A1A9HYN2|A0A1A9HYN2_9BACT Uncharacterized protein OS=Niabella ginsenosidivorans GN=A8C56_04650 PE=3 SV=1 ---LGKIALASDLELLKEETLHQLQAFMKTTGADSLQVVTVNKEVNNPASEERVSAIKALlqPLSPTFHFIKAENVAAGLETFVAQNNISLLVFTHHERGFFSGLFHKSVGKKIAWNTTVPVLRLK-- ->tr|C0QUL6|C0QUL6_PERMH TrkA-N domain family protein OS=Persephonella marina (strain DSM 14350 / EX-H1) GN=PERMA_0592 PE=4 SV=1 -FPYSEITISLN-CPDPAFNLEIGIELSRLMKLPFEVLYITMPQElrgdeEEEKLRERHEIVSDFEQiykTNIKYKVLEGNPVKETLKFMSDEsKRKNLFITTYDKNEEISIFKPHVQYHITKSIKNSVLLLP-- ->tr|F0S364|F0S364_DESTD TrkA-N domain protein OS=Desulfurobacterium thermolithotrophum (strain DSM 11699 / BSA) GN=Dester_0635 PE=4 SV=1 -TPVNKILVPVSGSFSSFRALEVGIELSILLDAKLTALYVRLNN-SDEKVNYLKDKIVKFSSmykISIDFLVRTGNPVNEFAKISKNY---DLSIVGARKGRKTNWFNPYPPYHMIHRSNCSSILVC-- ->tr|A0A1F2WKD3|A0A1F2WKD3_9ACTN Uncharacterized protein OS=Actinobacteria bacterium RBG_13_55_18 GN=A2Y75_07730 PE=3 SV=1 --RPAKMLVPLDGMPLPEYVSDTIFSIAEALHTDLDLLNIaaagkkpprvpgafpspayldHPYYDWPAWCSEFVKRILEEREPQVELTLfsKGGDPVRVTLQFALENSDDIVALHWRGLMSKKHA---ETVKGILRNAEKPVLLVRH- ->tr|U1PAD6|U1PAD6_9EURY Uncharacterized protein OS=Haloquadratum walsbyi J07HQW1 GN=J07HQW1_00535 PE=4 SV=1 -NSLDRLFVALGDGPEFDRILSFVADLLAAVDASVILFHTRE-----ETLTNATDQLVKRGVDsnRIYQQVSGGdNVRQRVVELED--KCDLLVIGEETPDPLNKtPVLETASTKMPLNTNDPAFIVRS- ->tr|A0A0S9LPP1|A0A0S9LPP1_9BURK Uncharacterized protein OS=Pseudorhodoferax sp. Leaf265 GN=ASF45_30210 PE=4 SV=1 ---HRSALVATGLDAEaAGPLLHAARWLCRPDG--VLACHVLDPTIQRhlhaadlplatvqswmetagrRAELALGQQLVQAGLPAGQALVLQGPALARLLHAQHSRAASLLVVGKPRRSRWADLLRPALARQLAARVASDVLWLPT- ->tr|A0A0S7YWS3|A0A0S7YWS3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_03420 PE=4 SV=1 ---MMKLLVYTDGKPAAAKALAFAAELKKRLVSELAVITVRSGTHATEepppvgidfpltdrnslpeglqALVDAIDVLEATGLmhrprsiriqdiarghlfvcrtvadERIAFYESFGHFIDSLNHEIERHQYSLLIISPQCLGKLQRLVKGDPVRKLALDLHTSVLVVRGG ->tr|A0A1V9FEJ0|A0A1V9FEJ0_9BACT Uncharacterized protein OS=Niastella populi GN=A4R26_25415 PE=4 SV=1 -SEFRKILFPVRPTLFSSKLFDVICELTRHNtqKCMLQLLGVVPGELkntisiLSKTVQEAKKQYNKEKFDIALSNGKSNDIAEYVLQRSKAINADLVVISQGLDLPSNPFFIGPFSQRIINHAKTPVL----- ->tr|A0A1F8P6A3|A0A1F8P6A3_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_48_7 GN=A2Z02_05505 PE=3 SV=1 --MFDKILVVMGLLSRTWSAIPYVRHLARGFGSEIYFLGVSTESQPvwdqslLGYIEGISRSLEEENII-VKTDFIHGNPAVEVVKYSKKNNISLIVTTAGTTNEITCSILSNISRRMGMELSIPILTVPP- ->tr|D0LX45|D0LX45_HALO1 Amino acid permease-associated region OS=Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2) GN=Hoch_3585 PE=4 SV=1 ------VLLPVANPGHARALVAVANALVPSNIGRVLLLTVLPRPQQdvaavgpdgataadaddilrrlkdaQEVVKNALTASYATGQAPEALITAAREPWREIERVASAHACECLLLGMSHGATTED---VVQVEGLINRVDCDVGILY-- ->tr|A0A1J5SVR0|A0A1J5SVR0_9EURY Uncharacterized protein OS=Marine Group III euryarchaeote CG-Bathy2 GN=BEU05_02935 PE=4 SV=1 --MFSKLLLPLDPSKRLKAATDYSLTLARRLKLPLVAAYIANPAKTGAgselqdpekcffplGERELKRFAASVSDVEMEPLLRCGERNVVLAHMVAeEQAGDTLVLGPFR-SRLTRFFTGSEVERILEDVQCHAFVVRHE ->tr|A6DMJ0|A6DMJ0_9BACT UspA OS=Lentisphaera araneosa HTCC2155 GN=LNTAR_15962 PE=3 SV=1 -MHIDNIITGVFSEHHFSMAVRESQKLANVFKAKVRPVHVIETLGLNpfypreteesrlealnKFKADVDHLYNKHGANHIEEPVVqIGRIHNELVNVANDYDNPLIVVGRHT-EGVMHKFLTTEAERIIAHSNTPVWVHPH- ->tr|A0A090VCV5|A0A090VCV5_9FLAO UspA protein OS=Algibacter lectus GN=JCM19300_276 PE=4 SV=1 -TCISTIVYATDFEQQDIIPITKLIEIVRPFEALIEIVHIYHTDTTtaRERMEQFKNMLLEQvSYEDMTFKTIaSDKIKSGIISVINSENASMLAMLERKHEFRlDNPFRKDLVKEIKTRVDIPVI----- ->tr|A0A0R2F9H5|A0A0R2F9H5_9LACO Uncharacterized protein OS=Lactobacillus similis DSM 23365 = JCM 2765 GN=FD14_GL000446 PE=4 SV=1 ------IVVALENSQNAHQIFNYALQLAKDYNKSVYGIYIINTVRELDctvdqrefwidsqeslakfNMEKRSQIAVRQGQ-HFISSITYGDPAVQIAKYVNLDNVCQLVMGRIGDRNLADDELGHKVASILKGIKKPVTLV--- ->tr|A0A0R2B7B0|A0A0R2B7B0_LACCL Uncharacterized protein OS=Lactobacillus collinoides DSM 20515 = JCM 1123 GN=FC82_GL002500 PE=4 SV=1 ------VVVAMENTKNANRIFKYAIELAEERHKAVYGIYVIDTVQNLPydedqwetwietqealgtfNMQRHSEMAAEADI-RFIWSVMYGDPVRKIARFANLDNVCHLVMGAYGERHLAMDLLGHKVPEILSHVRENVTLV--- ->tr|Q9HIM9|Q9HIM9_THEAC Uncharacterized protein OS=Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) GN=Ta130 --PYKTIYIPLSESVNTRGSVAFGLFLKKVTGAKVIFSDLrafdqNPTHKFSYVFDYMNEIIENFGGDiTVRKGGTSSDLKESILSEASNADADALVLGVRS-GPNGKIRVSSEIKDLMKTGEFDSILFK-- ->tr|A0A0D5ZHX2|A0A0D5ZHX2_9ARCH Uncharacterized protein OS=uncultured archaeon GN=IX51_10875 PE=4 SV=1 --PYRSIFLPVSENVNTRTAVSFALNLKIATGAKLYLADLrgydtKIRHGFKLLFDHFEEMLERFGRDiVVIKGGFSETLKEELKSLSERLSPDATVLGVRS-DTSGKIRMSSNVKATIKENPGDTILIK-- ->tr|V4HFX5|V4HFX5_9EURY Amino acid permease-associated protein OS=Candidatus Halobonum tyrrellensis G22 GN=K933_06148 PE=4 SV=1 -----RVLVPVRRMQDAPMYARLAARMGELYdePTEVWFLNVTEIPEQtyseqvfdvaqarVDRLEDVLAGVdDLDATFVVEGHVSR-DIAFDVLKTTRETEADRILMGYPSQHYK-------LAHELEYGSPCDVLFV--- ->tr|A0A0H2KME4|A0A0H2KME4_9MICO Uncharacterized protein OS=Cellulosimicrobium funkei GN=FB00_13090 PE=3 SV=1 ---PHHVVLALSDEDRQDDLVRYAVEEARLAGCPLRVVHAVQTPALVhalyedwgagepwksvatSRISAMVTPVAARAGVHTFLYVAEGPVADKVLSQVS--TKDVLVVGGRHHHPATARALGSVADRLLRRSPGTVIVVHPS ->tr|A0A0Q2UM69|A0A0Q2UM69_9RHOB Uncharacterized protein OS=Loktanella sp. 5RATIMAR09 GN=AN191_16685 PE=4 SV=1 --AYRHCAVAFDGSPEASEALRMALRVAPTARLTIVLTHDDSRSSArsdaeiriRSHVSSILAEFAERPAE-FELAPSDEAIVDAMKQVVEKLNVDLAAFGRTHRKGLAKLVQGGNTYMLLSHLTCDTLI---- ->tr|A0A1N7DRI1|A0A1N7DRI1_9EURY Universal stress protein family protein OS=Haloterrigena daqingensis GN=BB347_05555 PE=4 SV=1 -----RIFLPDFPDAtdDvTEQVLAFACSIKHRYGDEpVHLLRIQSTEARAgagdsdadsst--PGQFSGLEAAENTAINSDTTESEDVPATVAQTVDETETDLVVMGHEPSHASEGATFGRTADHVLAETSLPTYLVH-- ->tr|I4YDU6|I4YDU6_WALMC Uncharacterized protein OS=Wallemia mellicola (strain ATCC MYA-4683 / CBS 633.66) GN=WALSEDRAFT_60177 PE=4 SV=1 ----RSIMLAWTLDPAAQTALEYYITTLAMPHDLVHIVNVDTKGTGnlELELKERINQLEtqvAEGIQ-VISHTLSGETSSALVEFADKYSPDMVVLGRRNLGHWKRIASDegfSLSSHLATHIESPVVIVK-- ->tr|A0A136GVW8|A0A136GVW8_9GAMM Uncharacterized protein OS=Alcanivorax sp. Nap_24 GN=AXW13_09060 PE=3 SV=1 -MDGNGILVFLDRDLkAPQPALTKGLKLARAAGLPLTVMVNSDSAAMrravgldEERRQAAEKQIRKAwdkridalcGDHQVDKRIVsSRDSEQALRDTVRDCRPVLSVVHTSEEGRLRRHLFTPRDWLLIRHAPGAVLCVHSD ->tr|A0A1V5MFK3|A0A1V5MFK3_9BACT Universal stress protein family protein OS=bacterium ADurb.Bin425 GN=BWY75_00195 PE=4 SV=1 -----KYVVAFSSPKRSSKTIETAVSQARSTDAEIVLVRLIPDPGkvgivaqlissdrpldkARMQIDQCVEELKARGIK-ASGIVKMGEVAQGIIDTAKELGADMLYVGTTSVGGRQFFMMkkDPIVHYLVEHCPISLCLVRHD ->tr|A0A0P7XGL0|A0A0P7XGL0_9ALTE Universal stress protein family protein OS=Marinobacter sp. HL-58 GN=HLUCCO03_17045 PE=4 SV=1 ----NRIVVFLNdHDEANHRAALAAAEISRHDQQPVTIILGADGEPAGDQLDAIRQDLDVLGA-GTRLRVLADSNPLSIARMLREERASQLVISRESA-----LFHEPGADRLLAALSLPVTVTP-- ->tr|Q0A8H2|Q0A8H2_ALKEH UspA domain protein OS=Alkalilimnicola ehrlichii (strain ATCC BAA-1101 / DSM 17681 / MLHE-1) GN=Mlg_1516 PE=3 SV=1 -----PITAVIVrADEQAEAALRVALSVVGNRARALNVLVLPPEGgpVTDARLGEIAEWLEDQGV-SAHLRVVYPPDENGLLRALLQEQTGAVVITRNAH-----ETQADreMVSRLLERVDLPLLLLR-- ->tr|A4BTM8|A4BTM8_9GAMM Uncharacterized protein OS=Nitrococcus mobilis Nb-231 GN=NB231_00325 PE=4 SV=1 ----RPILVLYEgP-ETGDRALDTAALMARDANQALTILLPPSAEtQVERLEQTARNWARRHKT-AVSFMRLPSADAPILVQALRQTGGQVLILSRASH-----AVQNPAHRSLLDEIVLPVVVVP-- ->tr|A0A110B593|A0A110B593_HALHR UspA domain protein OS=Halorhodospira halochloris GN=HH1059_1540 PE=3 SV=1 ----TQLRAALlieaDsTSHSGLETLRLAHAMLGEHETLATVVVEPEND-SELIDKQLRPWLLDHYP-RARLISTTDIDAEQIAGIVADDCIGKLILSRRSQ-----LIHYEAAELLVDRLRIPLLVLP-- ->tr|A0A0S8BGF3|A0A0S8BGF3_9PROT Uncharacterized protein OS=Acidithiobacillales bacterium SG8_45 GN=AMJ68_10675 PE=3 SV=1 ----DAVVVLFDGSDESVRGLELARSMAASHEDPLSVVLLTRDAdIEKLQQQALEYVGATADV-DIRALPVSQ--LDQLPAILNITKCGVFLVPRSIS-----QTIDLLDIERLAHLRCPVMLLS-- ->tr|A0A0K0XTD1|A0A0K0XTD1_9GAMM Uncharacterized protein OS=Wenzhouxiangella marina GN=WM2015_533 PE=4 SV=1 ----GPMVLVLDsE-AGVERLLQQALRQARASRRDLIVLADPDLD----GLDALNTALAEQGM-QLHL--ARIRGPLSLLKWLQDLGGAQLLLDRGSP-----LLARMLNEQWLINLDRPLLILG-- ->tr|A0A0W1RWW1|A0A0W1RWW1_9GAMM Uncharacterized protein OS=Halothiobacillus sp. XI15 GN=AUR63_07605 PE=4 SV=1 ----AAIVALIGePQTSG-TIIETARLLARASDRGVRALLLPGADpA---ELPVLSSAPPADCP-AMTVERLAGRGLEALRRALRKQPAAALVLDDQAA-----LAFGIPMADLIADLDTPIIRIP-- ->tr|F9UGX3|F9UGX3_9GAMM Putative uncharacterized protein OS=Thiocapsa marina 5811 GN=ThimaDRAFT_4176 PE=4 SV=1 ----PLVGVLYSGSEGATRALAIALELVVRHAANLVVILQPEISaDTATLRGRVLEQLATLHE-QTRLVSLEGADAAGLSATVGKLGIDLLILDETNP-----LLARASLWNSLESLGCPVVIGR-- ->tr|I0HYZ4|I0HYZ4_CALAS Uncharacterized protein OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=CLDAP_01920 PE=4 SV= -----PFTVVHLGDAPSTHAVRLAAQLAKPRGASIHILALPQSRqQADEIAQEVAAS----GL-ECTVSTA--PSTEAMTALLTQIERGAVILPVSVA-------------PWLDLLSVTAIVTP-- ->tr|U7P8R8|U7P8R8_9GAMM Uncharacterized protein OS=Halomonas sp. PBN3 GN=Q671_17575 PE=4 SV=1 ----GPLRYFRGeAPALPWG-----------------------------ETPEEAVRRHPLFL---GREELAPMDAPALERFLARARRGALVITRARL-----ITLLEQDVDLLARIPVPVVVVP-- ->tr|A0A1F6TPK7|A0A1F6TPK7_9PROT Uncharacterized protein OS=Candidatus Muproteobacteria bacterium RIFCSPHIGHO2_01_FULL_65_16 GN=A2637_03690 PE=3 SV=1 ----SPVVALYDGSPASVQALELAARLLPDEEQRISVLVVADDPqQARRLEAEAAARLKKNGV-QARFRLLAEADGASLRRAIQSETPGTLVLAAGMT-----ALRDETIQELLEAGDCAVLLVR-- ->tr|A0A1E4I9K5|A0A1E4I9K5_9PROT Uncharacterized protein OS=Thiobacillus sp. SCN 63-1177 GN=ABS89_00460 PE=4 SV=1 ----GPVMVLFENVSASASSLAMGVMLARRNGAELVVLVSAASKdAYRAACAIARSALKDRGA-AGRCVWLPTLDEASLIQTAKNEMAGCLVLADRER-----FLRQAGFERMLDEIECPIVLTH-- ->tr|A0A1F4BA54|A0A1F4BA54_9PROT Uncharacterized protein OS=Betaproteobacteria bacterium RIFCSPLOWO2_02_FULL_65_24 GN=A3I01_15995 PE=4 SV=1 ----PRFVAVCTAAARPEELALSLNGLLRSSAEPVDIVLLCEDPvLAAQWERKARALLAETGG-PHKLRIAVAKDHAELLQLLSRRAGGSVQRFRERH-----Q----------------------- ->tr|A0A231MZZ0|A0A231MZZ0_9GAMM Uncharacterized protein OS=Zobellella denitrificans GN=CGX12_07370 PE=4 SV=1 ----EMVLAVWEEAARDAPVLARAEQLARQQQLPLWITVPAAGA------DELGPALEPRGL-KGAMLPITDWSLPGVM-AAASDRASLLVLHRDSP-----LLAGARMKNINAALLVA----P-- ->tr|F4L309|F4L309_HALH1 UspA domain-containing protein OS=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) GN=Halhy_2801 PE=3 -------LVALEMGKADESVLHFVHFLTQTLPIKaITFVHVLPKVDLFfndftqnmqnliknyghqdevlDQMRNKVSSfVDAENGPRLHFSIREGNPLEEVLQEARLSGADLLLVGQRSGTGN----HGILARNLVRKSVGNTLIIPE- ->tr|A0A0J1DBL1|A0A0J1DBL1_9BURK Uncharacterized protein OS=Massilia sp. WF1 GN=AB595_11200 PE=4 SV=1 --MPKPVLVISESPHPVAHAAARAAMLAAALQCRrmEFLCAARGAGTLCKGMEEVEHAGAAaqlrFGV-HCSAQFDTGAFPAALMQ--RALDADPLLIAAAwqAHEWWPILHNFNLLRDVSRASLTPVLLVR-- ->tr|A0A0P7WFI7|A0A0P7WFI7_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium HLUCCA01 GN=HLUCCA01_09575 PE=4 SV=1 --SMEHITVPVDFSAQSANATALALDLAGGSYDKVTLQHIYSPMKEFfpympaekekkaardKAIKAAAGFIREYKLNpDVDIELtlfREDRMSDEIYNLCNQRKSDLIVVGYRARKNLLASLKDNLPERMSGYGfGIPLLIVKN- ->tr|A0A1R4B6J8|A0A1R4B6J8_9VIBR Universal stress protein family protein OS=Vibrio sp. CECT 9027 GN=VPAL9027_02534 PE=4 SV=1 -KAPSRCIVAFDGRSHNLAFIRKILLMPLLHSMPLDLVIVNANEEERHYFQDAEAYWVANGK-EVSVTELQGNVAQELANYQLSRPDSLLVISASPHSRFLRFWLGSHTKDILCAAEGPVLIISN- ->tr|A0A1W1BCG6|A0A1W1BCG6_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MNB_SV-12-734 PE=4 SV=1 -REYKNILIPTDLSEKSKKSIEFIKNS---FDANLALVHGYESVTAtmsmydisyvnmveyqkenRDIALELFGAFQKEVGVEGELTDANFSLPHGVLEYIEDKKPDLVLVTSH--SSEESFFVGSMSSYLAKESPYDILI---- ->tr|A0A0S8CZ36|A0A0S8CZ36_9DELT Uncharacterized protein OS=Desulfobacterales bacterium SG8_35_2 GN=AMJ61_02320 PE=4 SV=1 ----MNVIAAINGQVTSEVAALYSLHFARIQGLPLILLHVANPDDSIAAVEKSMANIERAAAEydiVPERIILEGPPAETVKRYLSENKSEILFCSTRYRqrKKFFNLAFSEKLRSMSLPADLAEV----- ->tr|A0A1D2U0S4|A0A1D2U0S4_9BACT Uncharacterized protein OS=Verrucomicrobia bacterium SCN 57-15 GN=ABS95_02065 PE=4 SV=1 --GFRKIMVIIASEDTAAHCLDSAMMFFSTETSEIHFMSLAPRvAPELPHARPVRNGLATRKYPkPVEVFLHESvsiEPEQDIRRLAYSFEIDLIVMIAHPGPGLLSVFLKRADERILRAAPCPVVAVP-- ->tr|V2TQ14|V2TQ14_9GAMM Uncharacterized protein OS=Acinetobacter nectaris CIP 110549 GN=P256_00581 PE=3 SV=1 ---MKRVIACVDSSPCINAIAEAASWIAKRTQRELVLLQVLDYYPASyhlgeisgvigfesnamllkelaeleekqstlavdysnNLLKHLITTIKEKHGIDASVIQEKGDFLEQSLGVLR--EDDIVLIGKVGESAAEKnKVLGSNVENFVRGANCTVMTVSDH ->tr|A0A1H1KYR0|A0A1H1KYR0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Gillisia sp. Hel1_33_143 GN=SAMN04487764_0160 PE=3 SV=1 -RLLNEIIIASDFQEDSKPTFDLLFKFALSIKLRVKLLYINVPYNFketPEIELSIQKFMEDKVVDRVETFIVdALNEKRGIAIYLAKEKPDLIATITHGRSVINNLFSPSITESLLSTFNYPVLSINMN ->tr|A0A0C2MJ77|A0A0C2MJ77_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_06520 PE=4 SV=1 ---MKNILLPIDFSCDVQQAVDFVINFVPKpyklvfvnayvceldgvfkefeyhiSDDQLHLILATVSTDFQDKLSKMEIIKKKYSILcSVETKILFAKgmgVREAVSHYLKEQKFDMMVIGSKNPSSFFGYIFKSFAADMLSESKVPTTIIH-- ->tr|A0A1R3X844|A0A1R3X844_9RHOB Nucleotide-binding universal stress protein, UspA family OS=Pontibaca methylaminivorans GN=SAMN05421849_2573 PE=4 SV=1 -----HVLIASEGRAVSDRVISRAADLLPGGKGRVTVLTVArlwgtsfglpnpglrpskrEMDEQKEIMTSALDRLEALGIEADGHIVTTRHPAKSIRRKLHKGDFDAIVMGADPRRPWfmRGFMWSQEPWRVKATMPVPVHLVCPD ->tr|A0A0F5HLT3|A0A0F5HLT3_9BACI Uncharacterized protein OS=Bacillaceae bacterium MTCC 8252 GN=QY95_03960 PE=4 SV=1 --MYSSILVYADDAEHALEAVKHVQ--QPSHKLEeVTFLYIHPVSAHLpeslpdrirlveqlyahsDFFHEAKDYLDKLNIK-HKTVIRMGNPAQEISLITQFDRYDCLVVAKAA--------SEEAAAAITQKAKCPVVHVD-- ->tr|G6F1J7|G6F1J7_9PROT Uncharacterized protein OS=Commensalibacter intestini A911 GN=CIN_14930 PE=4 SV=1 -MENTKVVACIDQSTYSAYVTDYAAWITNSIHKPLELFHIGDCPPInaptdtaqktprRKLLNIYYERALEKGVDPslLQIHEEYGSFKEKVIRYED--NIDLLVMGRRGENTEKKhqDAIGKSIQKILRVLHKPVLTV--- ->tr|W7DSX7|W7DSX7_9PROT UspA OS=Commensalibacter sp. MX01 GN=COMX_08555 PE=4 SV=1 -MENTKIVACIDQSTYSAYVTDYAAWIANSIKQPLELLHIGDCPVPssqidvnkktprRVLLNTYYERALATGIDPslVEIHEEYGYFKDKIIEYEA--NIELLILGRRGEDTQ-KhqEIIGNSLTQIIRTLHKPILTI--- ->tr|A0A1G3GYI1|A0A1G3GYI1_9RHOO Uncharacterized protein OS=Rhodocyclales bacterium GWA2_65_19 GN=A2040_12110 PE=4 SV=1 --KYRRILALVDANSDSAAVAQRAVQLSRFYGATLALAMVVESTPDLksnhapsfvtdemhqarmrDIRCKLEQMMSEIGCdCGCEIIIACGSEPEVVADLTCSWRPNLVLVDCRARHGLEQ---------NSKRADYDVLTVQYS ->tr|A0A0D2JBC4|A0A0D2JBC4_9DELT Uncharacterized protein OS=Dethiosulfatarculus sandiegensis GN=X474_03805 PE=4 SV=1 ----NKVLIPCDLSPFTLMQIRAALhAFHGRSDVDFSFVHVTDSTGTAIERWQKIIKNFEMDPSTSLKVIKPGkelNVAETLLGEVRKGDYGSLILGRRGgLARVRRRIFGSVSERLLDQLP--------- ->tr|A0A1W1WXQ5|A0A1W1WXQ5_9DELT Universal stress protein family protein OS=Desulfacinum hydrothermale DSM 13146 GN=SAMN02746041_00097 PE=4 SV=1 ---MERIVVTVSDeGMEALGALARGISLARRIGARLYVLSLERPGsraagassrlfsvgdEVAERMQMLIEGARADGV-SVDIHISEGSYEEALVRFCREYRVTLWIVGIPDKHRRDHHEALMRIHKIRARLGCAVEIVHP- ->tr|A0A0K8QYA0|A0A0K8QYA0_9BACT Uncharacterized protein OS=Bacteroidales bacterium 6E GN=BA6E_10964 PE=4 SV=1 -LTFKKVLIPVDMRKQNKDSLLWSAYFGRHLQSEVIAIGANDNSkearkSIAAHLLSFKNHLTKTGVAHKIYKGSKGSLAiqREAFETAQAFRADLMILLGSSYVTWLDQLIGLPEEKIIKKAIdFPVLIVNP- ->tr|A0A0L8V2U5|A0A0L8V2U5_9BACT Uncharacterized protein OS=Sunxiuqinia dokdonensis GN=NC99_43820 PE=4 SV=1 -LRYKNVLLPVDFRKVMKDTSLWASYFARFNKADVTIFPATEKNkenatMIRKNVKFIKHLLANLKLGFQIKNSSKGSFGlpFDALQRCHDKQHDLLIMPSSKNISLIDLIIGLPEAKIIKKANhLPVLCINP- ->tr|A0A0D8JD36|A0A0D8JD36_9BACT Uncharacterized protein OS=Draconibacterium sediminis GN=LH29_11445 PE=4 SV=1 -MDYNHLLQPIDLRKEISDSSLWCSYFGRFNAAQIVTISANDKTreakqNVLKNTELTRKLYEKFKIVHKRFRGSKSSLRnvFEALELALASDCNLLVILGSSNITPLDLLIGLPERKVIKGAGkLPVMVINP- ->tr|A0A1F3F8H3|A0A1F3F8H3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWB2_41_8 GN=A2066_14230 PE=4 SV=1 -LQYKNVLVPVDYRKASKETSLWASYFGRFNHSLIQVIYARESDrdnenQLMRNVKFFQKFLSSLNVRLSLTEGKSSSWGicKETLENAQKLKGDVMIFSGSSTITLIDLMIGLPEKRIVQKAGnLPVMLINP- ->tr|A0A0Q7JT55|A0A0Q7JT55_9ACTN Uncharacterized protein OS=Angustibacter sp. Root456 GN=ASD06_14420 PE=3 SV=1 ----NRVLVTSVHGAAAGPAVQWAVQRAVSRHHPVHLLDRWSVHAMgpgltvgheyDAARQEALERhseameelrAVVAGRVPVTGELVEGRGVDVEYARSN--AGDLLVVEWDDTEH----------RPSLRYERCPVVMVPAP ->tr|B5IBQ1|B5IBQ1_ACIB4 Universal stress protein family OS=Aciduliprofundum boonei (strain DSM 19572 / T469) GN=ABOONEI_2194 PE=4 SV=1 -SEIKKVLLLTDGTAKSKRAENYAILLASSFGAGMEVLYIKDKKD-GEHVKKLDNVVWKASHWNIEVKKNIESMenKDALLSHFN--RNDIVVMGVGKKILFWRK-IGHIAMFVATHSPIPVIFVNS- ->tr|A0A124FMZ8|A0A124FMZ8_9CHLR Cationic amino acid transporter (Fragment) OS=Anaerolinea thermophila GN=XD73_0779 PE=4 SV=1 -NGLQNILVPIGNGPNARLALKLASDIAFQQNVNVTAIRILPQKASKETQEDELSQMQEIAESEIGSippymemrTILSNNVLDGIVGETEKKQYDLMIIGAAEEVYSPDYIFGKLNDVLVEEVSCSVLIVRR- ->tr|R7ZMP6|R7ZMP6_9BACT Uncharacterized protein OS=Lunatimonas lonarensis GN=ADIS_4455 PE=4 SV=1 ---PDKLIVFTDFSEPSQHAVQVSVELAKRLKRPLEVFHVLTAPPIPSmagvamrnellesakaeaelTLSSLVKRLEEAHKATVvkSSVIAKLGFEEAVERTAQASPNCLLIFGKKKRSALERMFVGSGLTSLLRRGEvgVPMLLVSPG ->tr|T2KKN5|T2KKN5_9FLAO Universal stress protein, UspA family OS=Formosa agariphila KMM 3901 GN=BN863_12740 PE=4 SV=1 -FKIQKIALVIGEDLiHDSKLLEVLLQVARRFKAKVDVLTVKQGVAEYgytivdEKNENAIMYYLENFYS-HHHFVDGPDIPTSIFKYAEEKNIDLISILPRNHTKGKTSSEGALTKALSEVSKTPLLVID-- ->tr|D1PEF3|D1PEF3_9BACT Transporter, CPA2 family OS=Prevotella copri DSM 18205 GN=PREVCOP_05601 PE=4 SV=1 ----EKILVPVKYPEYADNLMNLAFLVRNqKLNRGLICLNVVYEDKDmrynqeqgRRILEHCSQLAAATDVMTQTQVRIAANIANGIKHAFNEFQCSEIIIGMHMHPEVSPKFWGEFHQSLFNGLSRQIIMARI- ->tr|A0A083WNL0|A0A083WNL0_9FLAO Sodium:proton antiporter OS=Chryseobacterium antarcticum GN=HY04_04940 PE=4 SV=1 ----ENILLAVNHVKTVDPMTNLALLIKSkNTTENLFAVNIINEEKNdsskknaETLLDQVVEIGASADVKITPVTRYDTDIIEGINNVIKEYAITDLMIGIDEEKRFSPNFIYNLYSGYLNNNAANILVYHA- ->tr|A0A1G3P9C2|A0A1G3P9C2_9SPIR Uncharacterized protein OS=Spirochaetes bacterium GWF1_31_7 GN=A2015_00460 PE=4 SV=1 ----QRIMIAVSNNKTASELMNFAFLLRTkNSVEAVYPILVVDNSDDidlqiakgEKMLAPIVVQAISADIPVTPVTRADGNPSVGIIRAVSDLRISDIIMGWSDKAGFYSSILGGVTERVVKQIRQSVFITKL- ->tr|U5CA60|U5CA60_9PORP Uncharacterized protein OS=Coprobacter fastidiosus NSB1 GN=NSB1T_01535 PE=4 SV=1 -----KLLISINESPHMESFIRRSKNLSYTLGVPLYAVYFDSTGQLtnkeQEQLNKNISMAYRLGV--FVIRSTGENWVSSMLDVIRIEKITHLIFERLPNeKYIKRIFRRSELDRLISKCKnLDIYILSNE ->tr|M6Z007|M6Z007_9LEPT Osmosensitive K+ channel His kinase sensor domain protein OS=Leptospira santarosai str. 200702252 GN=LEP1GSC120_1133 PE=4 SV=1 -----KILAVINDGITSYSLLRYAKRLAYERNGELFAIYNQTRENLtkesLGQLEKNLNFARELGC--EILYAADKNPADSILRICEQKSITRVVMEKPSASRWNrWTSPAYKLAAVP---SrFELCLVPYD ->tr|A0A0D2VAI4|A0A0D2VAI4_GOSRA Uncharacterized protein OS=Gossypium raimondii GN=B456_013G072800 PE=4 SV=1 ----RRIAITVDLSDESAYAVRWSVQNYLRPGdavillhihptsvlygadlgSVKQKLKNEFDL-MTTKVNTLAQPLVDAQIPFKIHIVKDHDLKERLCLEVERLGLSAVIMGSRGFGAARRTskgRLGSVSDYCVHHCIEETkkKKITGE ->tr|A0A218Y2P6|A0A218Y2P6_PUNGR Uncharacterized protein OS=Punica granatum GN=CDL15_Pgr000272 PE=4 SV=1 ----RKIGIAVDLSDESAYAVRWAVQNYLRSGdavillhvrptsvlygadwgamdlsmregddeVSQQKLEDDFDTFTSTKANDLAQPLVDAHIPFKIHIVKDHDMKERLCLEVERLGLGAVIMGSRGFGASRKTakgRLGSVSDYCVHHCVCPVivVRYPYE ->tr|A0A0U2XLX3|A0A0U2XLX3_9BURK Uncharacterized protein OS=Pandoraea norimbergensis GN=AT302_16845 PE=4 SV=1 -PNVERILAAVDGSANGRFAAWIAGLTAGVRGTLTTVLAPAPDDAEEGtpdrsekkradaddtaneegagrhaydialsaamlaiprapgtpgvddkakdrkdaakEEKHPDdtakVLRREAErlvlrertgkapqktpelphgpvdndagdangaataasvdddrqrdadpapkhepvgeahddkrvsnatedgefvASDPsdaareqeAKQADTSHEATRISDEIGK-GYGFVIAGFDAPGEESD--------SDVPPLPLPTGVlpLTKA ->tr|V7FJM2|V7FJM2_9RHIZ Potassium transporter OS=Mesorhizobium sp. LSHC420B00 GN=X759_17930 PE=3 SV=1 -SRLERLLVLVDDSRIGKFTAHLAGLVGGGSGMPTTLLRLPTTLLQPKdgridrpsdskGQERALQEIKKGAkksaqavkriedtlvgKFHLTARTELEATGETIAEEARK-GYGLLLVGLDNVLT--------------ADGAFAPALndIAAG ->tr|B4D484|B4D484_9BACT Sodium/hydrogen exchanger OS=Chthoniobacter flavus Ellin428 GN=CfE428DRAFT_3722 PE=3 SV=1 -PRLQRALVAVDRSAAGEFAAMLAGWLIGSRHLSATIMETGEADSRPEeafspskrllesasg----------AAHkievreekemkehpperdpldaaahaahtqqlrIQDLitlmpakkRAHGGEDPMADSILTEAKN-SYELIYLAVGGYLLD-------------GSSKFPASVekIVRD ->tr|A0A192M7M8|A0A192M7M8_9RHIZ Na+/H+ antiporter protein OS=Rhizobium sp. N113 GN=AMJ96_PD00096 PE=4 SV=1 -SKFERILLAVDNSASSGLATRIAAHFTALRKMPITVLNIDGKPQGPEaqsggnkdeagrTIDNTAmaiaEQVRESAqrtvgrvgsqeaaidgDLHVTTSGTSGDLEALLAESAEK-GHDMLFVGVEPTAA--------------PEGGLDQKIsrMSKS ->tr|H2CKE1|H2CKE1_9LEPT Transporter, CPA2 family OS=Leptonema illini DSM 21528 GN=Lepil_3589 PE=3 SV=1 -HSLNRVLLPVRIDPEGassrIIEAGILNLLGSTNRLQIELLNIPYKAAEKQqgl-------------dylkkirpLFH-vekmILRAvPGKEPAAIILDEARA-GCDLLMLGAPRDN-DLRGGGLfnPIIDTIVRQSPCPTLVVSKG ->tr|A0A0F6W0E4|A0A0F6W0E4_9DELT Na(+)/H(+) antiporter OS=Sandaracinus amylolyticus GN=DB32_001372 PE=4 SV=1 -LRLRRAVLVPSDGTASl-LAARLLGLIGVRTPLEVSIVDRTGGESAAVryaeslak-----------------HPKGeLRTAQDEKTARRVEE-DADLLAMGAPPPR-KGISRFLfgPRIDRKVLEAKQPVLVVDAA ->tr|A0A1N7EAW0|A0A1N7EAW0_9EURY Transporter, CPA2 family OS=Haladaptatus litoreus GN=SAMN05421858_4179 PE=4 SV=1 -GSVSRVLLPTRCSVHAq-LAAQLLGHIGRNRDIEVTNMYVVGASESETdslagrirrrlskytsskytsdapsprsng-------------gpsatnspdpttnavaedcldnttrQLSLsqemvhNRVRpRRGTVGETVTRELHR-GYDFLALGMGIADGESGRNPGdengtgrktrdgngrplfeLGIEDVLRATSTPVMAVNAN ->tr|G8TB22|G8TB22_NIAKG UspA domain-containing protein OS=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) GN=Niako_5130 PE=4 SV=1 -SHFKKIVLPLTDEVPVRR-IKFATLLARTFQSTVYLVSLRKDGNAaEQVVNKTLEVIQSLSTIPVQCFLLEGkNLAKSTLDFSKRINADLIMANPLKEFHMPGWWNRITRKLLSYGSKIPVITVDKN ->tr|A0A1F3PPT3|A0A1F3PPT3_9BACT Uncharacterized protein OS=Bacteroidetes bacterium RIFOXYA12_FULL_38_20 GN=A2281_13820 PE=4 SV=1 -NKLQHILVYTDFTEVGDNAVKHAAEMARIFNKNLTILHVIDDNTNtlfkknteekvEQKLEEIAASVRQGCPFEVKTMYEEGCACKIINGTSETIDAVMVVLGVHEKNMI-QYITPKYALKKIAKSRIPYLLIN-- ->tr|A0A0L0D8W0|A0A0L0D8W0_THETB Uncharacterized protein OS=Thecamonas trahens ATCC 50062 GN=AMSG_00598 PE=4 SV=1 ------IAMAFDGSPVSLRALRMAHGYARKMGSSLHVCSVLTATRGESALTELmasalevepnLDALQAIGV-DVAFLDREGSVAETIMAHIEPLAPLATVLCTAT-IFHSEHLLGSVSRRMVRRGKFNILLVKPT ->tr|E6PH52|E6PH52_9ZZZZ Uncharacterized protein OS=mine drainage metagenome GN=CARN1_1188 PE=4 SV=1 -RMVGSIIVVFAENIASQHMMALAAKLAKGERSELLAIYVVSVPYSLppdaemtdeerralDALGAAQAIAAKADINLRTETVKARSTKQAVLDIAKRERANLIVLGSFREGKYTAAPLSRTIEEIAAEAKCDVLI---- ->tr|A4CPK3|A4CPK3_ROBBH Uncharacterized protein OS=Robiginitalea biformata (strain ATCC BAA-864 / HTCC2501 / KCTC 12146) GN=RB2501_02830 PE=4 SV=1 --------------------MEYALLNYPGEPIHVVLVHGFRSPDSkwgliqfstrsevrklrSEDFENALNRICRThgkSIGSVQTLLFTGRNTHAFKNAIEPLEITDAVVPENGT----------------------------- ->tr|A0A1M5QKL6|A0A1M5QKL6_9BACT Uncharacterized protein OS=Chryseolinea serpens GN=SAMN04488109_2859 PE=4 SV=1 --MRKTILIPTDFTITPLLLLKHVAATSA-VELDVIFLYCTSLPDSitdllfyspkkiieaavTTAFSEGCAVIQNKypeKIQSIRFELFHARSVDAFQIMAEMNGIDEAILAHTPA----------------------------- ->tr|A0A1M7B975|A0A1M7B975_9FLAO Uncharacterized protein OS=Chishuiella changwenlii GN=SAMN05443634_11090 PE=4 SV=1 --GNKRVFIPTDFSIQSLSVINQLVKESSNTVFDIVLIHGYQPSNTitdllffsknkmieklqKSAFVKAYEVIKNAnqsTISSIKLDIIPFKRNLYIKNFFENSNIDSFIIPSTQQ----------------------------- ->tr|A0A1Q3N001|A0A1Q3N001_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 47-18 GN=BGO09_12360 PE=4 SV=1 --MAQTILIPTDFSIDSIQVLREYLDRNAaQAGLQIVFAAGYDTGSSitsllfhsrsrilqkmnLESFNEALHIIENKysnLIRGIRIEFFSGWNQSSFRNFLAGNRIDHIVYTSDMR----------------------------- ->tr|C7P3H1|C7P3H1_HALMD Uncharacterized protein OS=Halomicrobium mukohataei (strain ATCC 700874 / DSM 12286 / JCM 9738 / NCIMB 13541) GN=Hmuk_1528 PE=4 --QWERALVPVRRAsDVAHSMIDFAIRLTGATG-EVAVCTCIGPSANRRRAESMLSNLANPFAAPIETRVARQEIVPFLRGTAP--AYDLVLIGASRDRSAASRFVAPPTFESIAEMDTDVAIVDRG ->tr|A0A0E9LZQ8|A0A0E9LZQ8_9BACT UspA protein OS=Geofilum rubicundum JCM 15548 GN=JCM15548_13104 PE=3 SV=1 -MATQKILVSTELDELSAKITEFAVGLSAQLGAsELILLNVIIPARVHTfsttgdistydthnvnlfntelmkkhqlLVNEEAMKYSSAQI-NVKPVVRFNESKTNLNSLIESFKASLVVIGSRDEDSLLSQIFGSHSDEIVKKTDYPAIVLKED ->tr|R5ENE1|R5ENE1_9GAMM Universal stress family protein OS=Succinatimonas sp. CAG:777 GN=BN779_01157 PE=4 SV=1 ----QSVILAIDFTDaaqvgkLDDYLFDAASSFAKSFDGTVHIANCVTPKNPglmggnlsqskivssgglesrvGVHFKLAEEFALKHKVPLENVHVVEGRIDEEIPRLCEKFNARMVCMGTTPRSTFLGSINSSAGEIVLEQIKGDIFIVNS- ->tr|A0A1Y1IE37|A0A1Y1IE37_KLEFL Uncharacterized protein OS=Klebsormidium flaccidum GN=KFL_004110010 PE=4 SV=1 ----KLVMLAVDSSLESRGAVMWAARSLINAGDEVVIFHAIKTLKEIptamgmvpfsganpemqrahmlvteenakKMAATHAAYCQTQKI-EAKTEVIWGQRRQAILDRVVQLGVTHLVMGTgKGSRRLSFLRKESLTATVSREARCQVFLV--- ->tr|A0A150PR90|A0A150PR90_SORCE Universal stress family protein OS=Sorangium cellulosum GN=BE08_45690 PE=4 SV=1 --RNRSVLVALHGERVHLGAVDLGRIIAGALRAPLHGLFVCSEPIDPSDVPAHLGVDPEALH-GVVLHVDASDDlPGALAEATERGDAAFVVVASePEELTDNRLGVGRLAARALEAAACGVVVIHP- ->tr|A0A150QCH1|A0A150QCH1_SORCE Universal stress family protein OS=Sorangium cellulosum GN=BE15_25600 PE=4 SV=1 --RNRNVLVALHGRRVHLGAVELGRLIAGALRAPLHGLVVSSEPIEPSDVPAHLGVDPEALR-GVVLHVHASDDlPGALASATERREAAFVVVASePEELTDNPLGVGCLAARALEAAACGVVVIGP- ->tr|B5WNY7|B5WNY7_9BURK UspA domain protein OS=Burkholderia sp. H160 GN=BH160DRAFT_4790 PE=3 SV=1 -NTFRRVMIASAGGAGLPSGTRVAQQFAA-ADARFRLVNIVCNPAAlyptlmlsypdwceahramlhgaQLALREAVTALHGVVAatdaEIVDLTVLHHGAAEALAHPAAQWNADLVVVAAHARE--HRWDSRIDPEELVASIGRPVLYLPPS ->tr|A0LHM7|A0LHM7_SYNFM Uncharacterized protein OS=Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) GN=Sfum_1237 PE=4 SV=1 --DPERAAICVLNEDASLRIADHAAFMLADTTVEITLLHASRTVPrmisahpagvmgeelgswlktpagqvIEPFLAESRQILRTAGIDESRVRVtlipDKGNTAMEILSHCREQGIGIVALGHSEPAGTWGFFKNSVTRKVLSEFK--------- ->tr|A0A0S8ITX3|A0A0S8ITX3_9BACT Uncharacterized protein OS=candidate division Zixibacteria bacterium SM23_73_3 GN=AMJ91_02360 PE=4 SV=1 -RKEYKILVPVANPGTLGMLMMTACAIAKKFDGEVIGLSVVEVPHRtplrkgladfsqqRLLLSRAENIARQERVKFDKLIKLSHRLSYGILETAEEEDCNFIIMGRSKPEKTLEKILTTVMDIVLKEAPCNVAIVC-- ->tr|A9B6K9|A9B6K9_HERA2 ABC transporter related OS=Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785) GN=Haur_0260 PE=3 SV=1 -KPCNKALICVSDGEPSKEDVAFAGRLLGSVGASATLVSVASHSNDIERLERFLQTsaasLRRHEVV-TETKVLVGNVAQTINAEIKRGGYDLVIVGAPLGAYSSNYDLGSVVGPLLSQISVPVLIIRSS ->tr|A0A223NY28|A0A223NY28_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Mucilaginibacter sp. BJC16-A31 GN=MuYL_2875 PE=4 SV=1 -MLMKNILFLNELKSQDDSTAKNALRLAYALRCDLILLCPFNEEGILknisddhgvcesfdlsrkelllnierqlKMLQPILDSSEGFRPQ-LQYLIKEGSIENSIAQIIKNDAVYMILIGTHHCMDFSNFLFGKYVNQIADQAKCPVLLIPSN ->tr|A0A124F8K7|A0A124F8K7_9DELT Uncharacterized protein OS=Desulfonauticus sp. 38_4375 GN=XD41_2003 PE=3 SV=1 -KRIKRVLLLLDGSKLSWQILRFGQWLARIFSAEVKPVYIEEPSLLPQkiyarevrffsfqvqrenffwqkevrfKEERVRKFLGQGEVSDLHLAKVQGNGEEVLLNQVT--SGDLVILGKRGWSKRGFFCVGSTATQLLKKGRASVLLL--- ->tr|A0A1C2GQZ8|A0A1C2GQZ8_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PPCGB 2223 GN=BEL04_06210 PE=4 SV=1 --GFKNLVFATDLSDGSVSALNSLCDMAKYFDSEIIITHISDRGLLAHNNTVLEKYFDRVDAEitypkKRFKIIKDTNILRGLKTIPQKLNADILAMVHRKRNYLQRLFNKSVSHAMVNYPVGPMIIFPA- ->tr|M0CWH1|M0CWH1_9EURY Cationic amino acid transporter OS=Halosimplex carlsbadense 2-9-1 GN=C475_06615 PE=4 SV=1 -----RVLYPVFGSESEAV-IHIGASVAQGTDAELVVGALDDvagEPSFDASRDLAKTVFRaqtdcALDVH-VQAVPLAGsSVLEGIVSGADTYDAGVVVLGD----EVTEPRESKLAGRIA----GDTVVVN-- ->tr|D4GQ75|D4GQ75_HALVD Cationic amino acid transporter, putative OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2 -----QILVPLLTREVPVLTdqLKVATTLARVTGASLTVIN-----PFPDPEQAP-NVYRheatdcENASlldwvfeqtdeslPQVESDFLYAwDVVRGVLQAVRRRDVDTLLVPSSSGT---SRLRKRMTEQLATHADADVIVVN-- ->tr|E7QSK7|E7QSK7_9EURY Cationic amino acid transporter, putative OS=Haladaptatus paucihalophilus DX253 GN=ZOD2009_08913 PE=4 SV=1 -----NVVVLSDGG---DAErtVSFAATLADARGGELILVNAAVrssGTPLN----LAGDVLNerqaaarrTLRTtvdsafdvr--TRAAARVGrNYLTIARTASEEFSAGVVVVDESESM-TSTAFGRSVSTRVGGHVDCDVISVG-- ->tr|A0A0B5H133|A0A0B5H133_9EURY Uncharacterized protein OS=Haloarcula sp. CBA1115 GN=SG26_17500 PE=4 SV=1 -----RILYPIFGTHDDF-TFETALNIADGVGGELLVLDLFTgdaTRSSETTS-----VGR---KllqarldetHTADAHliVEETdTPLKTAINVAQQRHVQLAVLDEHTPELFGEGLRGDAADRMRKKASCDVVSVT-- ->tr|M0L3Z0|M0L3Z0_HALJP Uncharacterized protein OS=Haloarcula japonica DSM 6131 GN=C444_17252 PE=4 SV=1 -----RILYPIFSTHDNF-TFETAMNIAEGVEGELLVLDLLDdnsIHSAETTS-----IGR---KllqahidedHTVDAHliVEETdSPLSTAITVAQQRNIQLVVFDEHTPELLGEGIRGDAADQMRKKASCDVVSVT-- ->tr|U1Q481|U1Q481_9EURY Universal stress protein UspA related nucleotide-binding protein OS=Halonotius sp. J07HN6 GN=J07HN6_02857 PE=4 SV=1 -----RVRA-----------AAVANAIATDRDAELLLTESVDvgeST--EAMLPLP-----ssHRDSHSIGATLLETsNTIQPIVNE---QDPSVLVMERASGTTFFSDLRASMAERLAA--ETDVLTVD-- ->tr|A0A0U5H0S3|A0A0U5H0S3_9EURY UspA domain protein OS=Halobacterium hubeiense GN=HHUB_2109 PE=4 SV=1 -----RVLVPFCEAANRA-EtSRLGASITFGSDGELYILHATDgeaSADAD--------ELRheaELELelreefsvPVTQFETEYSsGVLDSFVDS---HSITATVV-DREERGFFSRGRDEQTVA--S--GCHNVVGT-- ->tr|A0A100VYP0|A0A100VYP0_9MYCO Universal stress protein UspA-like protein OS=Mycobacterium brisbanense GN=RMCB_2516 PE=4 SV=1 ----KWIVVVLDETDSALDALRAAMREAGLRDAPVLVLESWshgrhtdtantARHPVRTVLEEYLTGPGASVDVQLSTLPMPTHLLHLLHQCV---SIDQLLVVAADHHALVEELTSPRAREILRGTDCSLLFTR-- ->tr|A0A0U1A6B5|A0A0U1A6B5_9MYCO UspA domain-containing protein OS=Mycobacterium abscessus GN=ERS075544_02233 PE=4 SV=1 ----GVVLIEFEDAPDSHAVLQHGLDAAAERDAVAQVVGHLpssptgsqtkddSAAILNARLERHLEPWRrKYPDTHVEVHLLHGGLPKYLSQQG---DSIQMAVIGRGRSGGLNELLRQQQATSNPGTGCTLMICG-- ->tr|A0A1A2S973|A0A1A2S973_9MYCO Uncharacterized protein OS=Mycobacterium sp. E2479 GN=A5686_21410 PE=4 SV=1 ----PGIVVEVDNSPDSAKLLGIAMEEARMRNATVHAIVCRrsvshdvavegkHDLRAVADLDRRLAGCRrRYPHVQVEAAAAHNTLLEFLGCNR---GSVQLAIVGSQNREHLQELVGPVGSAVLQAAGCSLLVVN-- ->tr|A0A0D3L9M9|A0A0D3L9M9_9BACT Uncharacterized protein OS=Flammeovirgaceae bacterium 311 GN=D770_00590 PE=4 SV=1 -NEIKKILIPIDFSAVSLNAIRHANSILQEHPAEVVLVYVNTPErklreqEILNSFRKFEENHLTGIFFSYSFDVRHGKLLNVLANVTLCHTPDYTIMGLRER----------------------------- ->tr|A0A162NFU4|A0A162NFU4_9BACT Uncharacterized protein OS=Flavihumibacter sp. CACIAM 22H1 GN=A1D16_06550 PE=3 SV=1 ---PQHLVLATDYQLADKKALPLLTAIASVFGADITVTRIISGHITreetakeqARFSEYSNLLQKDFAASSLSFQLITSsSIIDTLEHLEEEIPYDLLTMVRLKKTFLQRFFTESFTRNMAYLTRHPFLVMADD ->tr|A0A167WBT7|A0A167WBT7_9FLAO Uncharacterized protein OS=Flavobacterium fryxellicola GN=FBFR_11765 PE=3 SV=1 ---PKKITYASNYHKKDKKVLSYLLEINKLFNATISILHVDKGIMAftadEDFDKYKNTIENHFKDFEFSFKHITGeNVAKIILEETVADKTDLIvINPFKRKGFWNRIFYASITKKTAYLITKPLLSIPVQ ->tr|A0A0S1SEC4|A0A0S1SEC4_9FLAO Uncharacterized protein OS=Sediminicola sp. YIK13 GN=SB49_10610 PE=3 SV=1 ---LGHMVYSTDLQHVNEEI-ASVIPFAKLMDSWIHVLHINRGKEGfeGDLEEEEERLRKEFSYQKIKFREFKSsSIIEGINKFISVVEADMVVMFTHHTNFLEKVFQKSVTQNTAFQTRIPLLTFQKE ->tr|A0A1E7IR31|A0A1E7IR31_9DELT Uncharacterized protein OS=Desulfuromonadales bacterium C00003107 GN=BA869_04910 PE=4 SV=1 --PFKKILVPIRSKDTIKKAFKEALLISSVAMGEITVVLTGETD-----GQEMEFMAREMGV-PLKIFQEKDEQrgvirkylrnpsciiLDTVKEHFY--YPDCIMVDPEELGIIDRLLGRGIILRLIREASLPVLVART- ->tr|A0A1F2P7P5|A0A1F2P7P5_9EURY TrkA-N domain containing protein OS=Candidatus Syntrophoarchaeum caldarius GN=SCAL_001665 PE=4 SV=1 --PFDRLLVPHIAKTTAEKAFKEALLIASASRKKakIEVVSYDRSE-----QKMMEKKAKKWDV-P-FEFLlDEGELIDMLKHNIH--NTDCIIVDDEKITILDRIFPRNIILNLMRSVTSPVLVARS- ->tr|A0A1E5T128|A0A1E5T128_9BACT Uncharacterized protein OS=Fabibacter misakiensis GN=BFP71_16480 PE=3 SV=1 -KKFSKWMVGIDVTKNEVNLLRNVSELANQFtPDAIHIVHISKeldipkevlvdiPDLMMPDIKQAQASLEEmvakyfHPEQPVEIHVLSGNQLTELLRFENTHKIDLAILGRRNMNR-----VGVLSKKMVRKSACNVMLMPD- ->tr|A0A1R1YNL7|A0A1R1YNL7_9FUNG Uncharacterized protein OS=Smittium culicis GN=AYI69_g2058 PE=4 SV=1 ----RVVMVCVSGSKTsSEQVVDKSVKMVLNKNSDLVILLHVRKSNEncgytgqdefipgqadmnntfkaesYEILTNYGNKLKNLGYVIRAISVAGDDPGSEIAKKVSELSIDLLVVGKPEKSGISYFLSGNSCEKLFKQCDCTITLIKID ->tr|A0A0M3C3C6|A0A0M3C3C6_9SPHI Uncharacterized protein OS=Sphingobacterium sp. IITKGP-BTPF85 GN=L950_0227890 PE=4 SV=1 ---YKKVLLAVDLSHLHERLpVKMIFQMQELLSLEWHVVNVSIQGqHSAAQLIEEQSFLHSSldSLEPTYSYLEGEDIVEKINTYVEDHHIDLLVTAPRKLGFLATLFRKVLLKVSCSHQSTNIDV---- ->tr|A0A1V8RPF5|A0A1V8RPF5_9RHIZ Uncharacterized protein OS=Pseudaminobacter manganicus GN=BFN67_20225 PE=4 SV=1 ---PRQVLVASEGRRISEDVIQLAARIARGHDGRVRVLSVARLWGTsfglpnpglkpsrremaeqEDNVAQAIERLEALDVIADGHIVVTRHPAKSILREAGRLNCAAIVMGADPRRNpvVGSMMWSQEPHRVRRSAPIPVHLVGAS ->tr|I4VHZ4|I4VHZ4_9GAMM Universal stress protein UspA OS=Rhodanobacter sp. 115 GN=UU5_20535 PE=4 SV=1 ---MLDIIVKVDHAPSHPAWLDGVLALARRQQAFLTGLQVTVACLDtsdtiarsagdnddrAHGRRWWLELCRKADV-NGEWEVIHTAIPEVFAKRSC--LADFGICELRIGAADAPAGLHEVTH-TLFAHAVPMLLVPDI ->tr|M5D5K1|M5D5K1_STEMA Uncharacterized protein OS=Stenotrophomonas maltophilia SKK35 GN=SMSKK35_3908 PE=3 SV=1 ---LRDIAVLFDAGDTGHRVLNIAARLAQVQQAHLIAVSTAQHPSDiasgfargagiaaaldhearadaACTAQLMQNLRAAaepLRI-STELRIVSDyLGGADLSLHSL--YCDLIVAGYPQT-PGAPSGWHPLG--TLRQTGVPMLLVPPH ->tr|I4VHZ3|I4VHZ3_9GAMM Universal stress protein UspA-like nucleotide-binding protein OS=Rhodanobacter sp. 115 GN=UU5_20530 PE=3 SV=1 ---MLDVLVNVDEARDDAAIIRLGMDIGRRHRGFVTGLRIVDAYPLaiaipgalvvldaeereaKEQRAWWDGLCRRHKV-AGAWEVIRGIRLPILARRSC--LADLTIDRLPSAGNGMLVSMDNVTR-TLLAGTSPMLLVPSV ->tr|A0A101JB32|A0A101JB32_9ACTN Uncharacterized protein OS=Actinoplanes awajinensis subsp. mycoplanecinus GN=ADL15_45800 PE=4 SV=1 --RGTVVAAAIDDDAHADEVLAHADRRARERGATLRAVHVWTGRGAVvgglrvrphglsyadlLLSTALYDGLDPGDAAAAEREILHDrDPARALRRLSR--ELSLLVVAAASEQVTPARPFGSTVGGLIGRTTCPLIVVSTG ->tr|V4J6T1|V4J6T1_9DELT Uncharacterized protein OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_04585 PE=4 SV=1 --QLSRLLLPVDSLAAFERTLPLAEVLIRAMAVerkKVALLHVVSGSYLRDymegisvdrgdlpdteqmkqlrrrheenvvkpLMRQAGVLLHKTSGIeQAATIIEHGDPIKVIGEVCREGSFSTVVMSRQNEAERGGKLTGSVTAGLLHR----------- ->tr|A0A1M5WS29|A0A1M5WS29_9DELT Nucleotide-binding universal stress protein, UspA family OS=Desulfofustis glycolicus DSM 9705 GN=SAMN02745124_02506 PE=3 SV=1 --PLSRLLLPVGTMETFERAAPLAGLLIRTMEIgadRVDLVHVVAGSFLGKrfksvdltagetvsteelqrlradylaetaepLLATCTRMVQQESAGrIPAQLLRDGDPAKVIGSLCAEHGYSTLIMSRRRIPAGTGWLTGSVTASLLHR----------- ->tr|I7LJB1|I7LJB1_METBM Uncharacterized protein OS=Methanoculleus bourgensis (strain ATCC 43281 / DSM 3045 / OCM 15 / MS2) GN=BN140_0879 PE=4 SV=1 -PEVRSILIPLDLF--VHDISDEAIDVLSTYNATISLAYITDARVIElleqaldhasteefrakkeeygrELLERTAAKLKGHGI-TTQTRMFVGHKGDDVVRMAK--NYDLVALCRRyADGESTDVSISPTVLRICQRVATPALI---- ->tr|O59574|O59574_PYRHO Uncharacterized protein OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) GN=PH1911 PE= -PTVTRILIPLDRY--SDPLPESVIEYISSFPgSRVGLIYVIDEDVCRviretigdkdaeifrekefkkgeETLNATKKLIEDLNL-NHiiSSQIKIGNKATIIEHESE--DYDILIVSRYyGATMVKTYQVSPIVFRILQNVEKPVII---- ->tr|A0A0Q9S274|A0A0Q9S274_9ACTN Uncharacterized protein OS=Nocardioides sp. Soil796 GN=ASH02_01290 PE=4 SV=1 -------LVAVDGSDASVQCLVWALHHAAVHQLTVEVVTIWPSRHTvfvhevaghfsaprwkardaqRQVIRKALAQVPRGSI--HAARLENGRVLDSIVQASA--RCELVVLGAASGDEPHPL-----TTRVAEQAECQVVVV--- ->tr|A0A1M6BAZ5|A0A1M6BAZ5_DESDE Nucleotide-binding universal stress protein, UspA family OS=Desulfovibrio desulfuricans GN=SAMN05660830_00010 PE=4 SV=1 -----RILVAYDASQSARDALTYCRELVELIADkcggkyTILVLTIEQLPACSlfssmgawkeqcakahkkqlLVHEQIVDEVKQSGLdpscitnkfvtlderdEPLEDSERKRLIAKAILKELKQGHYNTLVIGRRGVTRSDAYLFGSVSQYLLQEAKKCVI----- ->tr|C6HXJ0|C6HXJ0_9BACT Putative uncharacterized protein OS=Leptospirillum ferrodiazotrophum GN=UBAL3_92050190 PE=3 SV=1 ---YRRILIGSDLSRFPADIIEEIRKLAAHGDPifpeEIHLAFVLEalqdipidlPMAGLNLLPVAEEALGRLNLiardlgsmpTRISTGVYHGKADKILASLAAVLKFDLILVVSHGRPLINRLMTGSLPGSLVHISPVSVLVIKD- ->tr|I7Z9G3|I7Z9G3_9GAMM Uncharacterized protein OS=Hydrocarboniphaga effusa AP103 GN=WQQ_35170 PE=4 SV=1 ----------ISGQETRLDHVREAAALAQRRGAELHLMHALPEVSEgmliealysdrplsesvaGQRLADIASQLG-NEL-PIRLHIGTGEPESVLRKLLKRTQASILVVDRG--AVMRKRLMQASFNSKLADSPCLLICVPPR ->tr|A0A0Q5GH87|A0A0Q5GH87_9XANT Uncharacterized protein OS=Xanthomonas sp. Leaf131 GN=ASF73_07840 PE=4 SV=1 ----------ITGRETSLDSLRDAAALARRRGADLHLLHVMPDISEgllmdslfndqpltesaaSHWLSELAAQLQDDDL-CVRIHVAVGNPRREIAGLLKRARADVLVVEHD--AVVRRGVWRSSLHTALAKTPCVLICLPPG ->tr|A0A0F2QXJ2|A0A0F2QXJ2_9DELT Universal stress protein UspA OS=Desulfatitalea sp. BRH_c12 GN=VR64_13310 PE=4 SV=1 -KAWHGITVFYGGSSNAETALRWGVHLSEKSGRPLDLFTYADIrnaDRPDARLQASGLWDRVRPLLRTWHKIDQGGFKESLYAVD---HDALLVVGAYGHGLLKDFVYGSKMEVIQRWMPNNMLLIGPH ->tr|A0A1F3IXP0|A0A1F3IXP0_9BACT Uncharacterized protein OS=Bacteroidetes bacterium GWE2_42_42 GN=A2W94_08960 PE=4 SV=1 -----NILIPYYFDVLSDFALQEGIALSKAFKTGLVLFHCNPDESIKLRLAEIANNIISNHEIHTECFIPTGKADELMFALAHKTESILIIIGHNSNNSSLGFSLGKTL-RVMRKSRTPFLMVPEG ->tr|A0A1V6HY24|A0A1V6HY24_9BACT Uncharacterized protein OS=Bacteroidetes bacterium ADurb.Bin035 GN=BWX61_01318 PE=4 SV=1 -----SVFLILNENNFSTAALAQSIIYAKSFGAQLTI--CASPGFNKDILKKLINYVNNEFKIPAMGLQLDMPLKEWLIQASSKYEAIFFVVSLIDNKTSLGTNISQTL-HFFRNSRVPLILVPNK ->tr|A0A1Y6CLA0|A0A1Y6CLA0_9PROT Nucleotide-binding universal stress protein, UspA family OS=Pseudobacteriovorax antillogorgiicola GN=SAMN06296036_12681 PE=4 SV=1 -----RALLALSLSGNEDHVIRYAISLCERSDMDLELCHILPNTTPYvyesayfpeslypvkdpmirqaraeDKMNEIMARFNSDCI--VARTIRRGWFEDELVDLVDHHQASLIIVGRENDYRSIVKRMTSGLVSLVKTAHVPVLMVPRG ->tr|A0A170QBR0|A0A170QBR0_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MGWOODY_Mmi1610 PE=4 SV=1 ----MKILIAVSSKEYSGPTLSVGMNISRAFKAPTTIVDVGEKInefstkdvgmaherieswdfyrPGVDVLEWAFDYLADKEFiersdieagfpkntlvdiggnrcevylkgtvcDNVNLILRNGDIIAELKDEVQKHHYDVTIIGGSQKRRM--------AHDLIQYIDSSIFVVN-- ->tr|A0A1Z9L3U7|A0A1Z9L3U7_9BACT Uncharacterized protein OS=bacterium TMED190 GN=CBD50_04825 PE=4 SV=1 ----MKFLLAISSKDFSGDTLHIGSQIALAFNAQLSIVYVGPKPkdlylnrvkqaqqnlekweiyhPGIEVLKWAFEKLKDSGFiksknlndfnpanilessgrykiilptsygQKIDLILREGDLIEQLRSEFKQEKYTIGIIGGSKQRNK--------SNDILQFLPSSIFITN-- ->tr|R4Z4M1|R4Z4M1_9ACTN Uncharacterized protein OS=Candidatus Microthrix parvicella RN1 GN=BN381_80175 PE=4 SV=1 ---MNAITVAFGTHDSSIEPLTWSARLAQHLEAPLQVLSIVAPVSAEappeffaeldqRRRQDIEQATKNAGAASADVVVLnEHKPLAAIASYVNEHQPTMCVVGTHDSHEPGGLGEGNPAHHLLHHCHVPVAMVGPG ->tr|A0A0G2ZV39|A0A0G2ZV39_9DELT Sodium/hydrogen exchanger OS=Archangium gephyra GN=AA314_07089 PE=4 SV=1 -----TVMMCVSHGQSGAGMVTLGRALTGapQEPSQLYALHLIRPTERASFHLRHDPekasgdslapligRASGLGLQVRPLSFVSTEPGPDICRTAEAKQADLILLGWHKPLFS-RTLLGGTVHEVMQAASTGV------ ->tr|Q54CP6|Q54CP6_DICDI Nhe3 OS=Dictyostelium discoideum GN=nhe3 PE=2 SV=1 -----NILLYISNTRVGTALTNIAAAITPsdeesKKKYRVKSLFLHPISDRPSSYFYSTSnniknlpaqkreaveaiqnDSQEVGLPFKPIF-inS-TDPAQDISSVAkKNQWPDLILLGYTRSEVANegisSlgqsggffggggsggsdgqAFYGKVIVKVLQTCKSCV------ ->tr|F0ZZ47|F0ZZ47_DICPU Putative uncharacterized protein OS=Dictyostelium purpureum GN=DICPUDRAFT_58099 PE=4 SV=1 -----NILLYVSTNRVATAMTHIAAAITPstedsKKKYQVKSLFLNSTSNRYSSYFYS-SnninnlppqkkeiyrslqsESNEVGVKFKPLF-vnA-TDAAEGVTTIAKRQWPDVVLLGYSDRGDDQt-vdeshhagteTFYSKLIIKTLQTVKSCV------ ->tr|A0A0H3K1R5|A0A0H3K1R5_SYNP6 Na+/H+ antiporter OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) GN=nhaS4 PE=4 SV=1 -----QVLVPLANPQTQRQLLSVAADLALsdRGMGVIYPTNLLEINNDYGFDDMPVEveaelqnlhqgmarllgELRLPPAVVLPIIRSSGNVGRDLCQLADQAQADLILAGWHRSTVG-DSRLGGRVGYLLNHAPTDV------ ->tr|A0A1G0Y1C0|A0A1G0Y1C0_9BACT Transporter OS=Lentisphaerae bacterium GWF2_49_21 GN=A2X48_09720 PE=4 SV=1 -----RILISFGPALTGVRLLRLAGEISPksEHQSNITALHLTQGTDMHPIHADGYAqesfqplldEAKVSGIKIETLYKVTDDIEQEILDISDSQNYDLILIGSGKSIYK-GsllgsligmmnilsfrnilrvikgkppiikkdSLIHEKARHLIENAPCTV------ ->tr|A0A1H6API0|A0A1H6API0_BACT4 Transporter, CPA2 family OS=Bacteroides thetaiotaomicron GN=SAMN05216253_11377 PE=4 SV=1 -----KLIFCFGRPESGRSLLSIYDLLFGkqLKKEHVIAAHYTVGTDLNPLDAQHYEsesfallnqRAVELNIQVDNHYRVTDKLVQEMIHFIRKEHPDMLLLGAGSHYRPEmpgtPgailwlTLFRDKIDDIMEQVKCPV------ ->tr|A0A1J3HPP3|A0A1J3HPP3_NOCCA Cation/H(+) antiporter 19 OS=Noccaea caerulescens GN=LC_TR7375_c2_g1_i1_g.25089 PE=4 SV=1 -----RILTCFHSSRNIPTLINLIESSRGtgqKGRLCVYAMHLMELSERSSAIAMVHKarnnglpiwnkierstdqmviafeaYQHLRAVAVRPMTAisDLTSIHVDICQSAHQKRVAMILLPFHKHQRAD-gamesigHGFHLVNQRVLQRAPCSV------ ->tr|A0A1J3CRQ1|A0A1J3CRQ1_NOCCA Cation/H(+) antiporter 20 (Fragment) OS=Noccaea caerulescens GN=GA_TR19490_c0_g1_i1_g.64483 PE=4 SV=1 -----RILACLHGPANVSSLISLVESIRTtkILQLKLFVMHLMELTERSSSIIMLQRarkngfpfvhryrdgechssviggfqaYRQLGRVAVRPITAvsPLPTMHEDICHMAETKRVTMIILPFHKRWNVD-hhqdggdgnvpenvgHGWRLVNQRVLKNAPCSV------ ->tr|K7VU58|K7VU58_MAIZE Uncharacterized protein OS=Zea mays GN=ZEAMMB73_283365 PE=4 SV=1 -----RMMACFHSTRNIPTIINLMESSRGtrKRGITVYAMHLVELSERSSAICMVHKarrngmpfwnrrrngdgggdqlvvafetYQQLSRVSIRAMTAisDLETIHEDVVTSAHQKRAALIVLPFHKLHQID-ghmeslgDQYQHINQRVLHHAPCSV------ ->tr|A0A1C7MYR1|A0A1C7MYR1_9FUNG K(+)/H(+) antiporter 1 OS=Choanephora cucurbitarum GN=kha1_1 PE=4 SV=1 -----CLLSLVNKAESIPAVMALIQLMKNnpLSSIEIHALRLLELTERASAVMKYKDmqydpvlnvlftFAQLSHLHALLktHLDycLSTDYIKTVCRYRSEVNADMVVLPLMDPEA-----DLELIHELFG--iqHAPV------ ->tr|A0A1J7IAM1|A0A1J7IAM1_9PEZI Putative K(+)/H(+) antiporter protein OS=Coniochaeta ligniaria NRRL 30616 GN=CONLIGDRAFT_584407 PE=4 SV=1 -----RRLLVYLRLDSLPSLFTFITLLGAetshaaqeaaaasatedtvhirKRPLEVHGLRIIELTERTSSVMQVTEgeeyysahdpvvnafrtFSQLHDVAAAGRVAvvPVDSYPETLMSQAADVSSDFALIPWSEYGSVTedqsVpyainaserfksGTHLDFIQKTLARAtqTCNT------ ->tr|A0A1M5E002|A0A1M5E002_9PORP Transporter, CPA2 family OS=Dysgonomonas macrotermitis GN=SAMN05444362_109107 PE=4 SV=1 -----KILVSFEESIVGRKLLLIANSFVKkdQQYSEIDMVHISPGNGLYQHDMEDEEhdvfepvifASKALNQPITTIFEVASNPTRKIAKMANEGSYDFLLINAHNSIYGGkGnilgymlgvsnkilhiptriyswmtktkkaaktnsISLDEGTRSILTHSNAPV------ ->tr|A0A1T4L2X6|A0A1T4L2X6_9PORP Transporter, CPA2 family OS=Porphyromonas circumdentaria GN=SAMN02745171_00287 PE=4 SV=1 -----RILLAFGRSDTGPTLLRLAHQVFSrkDLSNGLSLLHITMSYNISVIDEETFFeenfeesieEGKRLSLNVHPIHKVSDQATSEIIHCANNGEHKFLLVGAGLNLSDSeidKsiisehqslqkfwgklsvntpeallnarTMFNDKMARFAEDSKCSL------ ->tr|M0QDD0|M0QDD0_9ACTN Uncharacterized protein OS=Gordonia soli NBRC 108243 GN=GS4_03_00660 PE=4 SV=1 -SGSGPIILGYNGSDASMAAIEATARLAG-RGAEVAVVSAVVRRGSRpqptplhdvlkaeayllsdhaavgELVRRGRETAVAHGLRPLEPIIAEGDPVRALVGAVRDLGASTVVIGRPDDP--GRRVPGPLARALRRHLPDDVDIVATD ->tr|A0A017HER8|A0A017HER8_9RHOB Uncharacterized protein OS=Loktanella hongkongensis DSM 17492 GN=Lokhon_01615 PE=4 SV=1 -TPYRRVLVAVAPGPASETAIPVIRAIA--PHSAIELIQVVPLDRDAetlcgsasgaatsvtpEQDTRAIEDLREKMGLALNTEMPdlKGDPRIKIRQKVSSDRTELIVFVNAGA-------VLDLKDSFIRTPPCDLLVCPT- ->tr|H1YAQ6|H1YAQ6_9SPHI UspA domain-containing protein OS=Mucilaginibacter paludis DSM 18603 GN=Mucpa_5443 PE=4 SV=1 ---MKPILVINDHSPQAEHAARMALLMAQRLHADLLLANCHAYEWQMlekavagsfnkdtgyhhyendlrDELYRLSHTSTGFKPE-ISPIDLSGSSEAALAGFVMGHEVEMIICGVGPGTGSRESHISSGS--LLRKVNCPILLVPYG ->tr|A0A223NQ26|A0A223NQ26_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. BJC16-A31 GN=MuYL_0070 PE=4 SV=1 ---MKTILVINDYSAEAANAAKMALNIGRKVAADIIIANTVKVNEKTqvkgglqmagsstivpdepevnlvTQLESINGSEDDYKPV-ITVIDASLFSETNLAELIIKNDIWLMVKGIRNNPGanQSGYSLNAQA--VLNRVRCPLMLVPES ->tr|I4AN61|I4AN61_FLELS Universal stress protein UspA-like protein OS=Flexibacter litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / S ---MEHILVPINFTPATEISLAHAVGIAQTSHKVIIMCYFVTSTVplganavlhkreikekYKKAYMEMRVLLSQYenhtyngtgQPVMIEPLVMEGHPDDATEKIMQDNSIAMIVLSHKDSNEIKDLFLNN---KVVKEANCPILTIPKD ->tr|A0A150GUF6|A0A150GUF6_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_7g945 PE=4 SV=1 --RPARYLFATDGSHAAHLAFCFLVNYLMRPADRVTVVTVTGTDGASEakllsGYSDYMRKHKVTGDVSVKCIDRlSNTVPEGIVEAVADHGCDVLAVGISGYGRKK---LGSVSTDISTRASCTTIIIKDS ->tr|A0A1C9W7N8|A0A1C9W7N8_9GAMM High-affinity choline transport protein OS=Microbulbifer sp. CCB-MM1 GN=betT_1 PE=3 SV=1 -APIS-ARNPVV----WQRRLKNALQLPTLAEVHEFIHDVGKP-SLEEFAEEMRksgytatvtEGenhyvelevlhgeelsfiyglqpkatlkpetdnpdkvlDDSRDDGSSDV---YFRADVHLFEGGQDYD----VMGWTKDQI-----LTDMVSQYERHLQYlhtlr-------- ->tr|A0A1Q9UQ09|A0A1Q9UQ09_9MICO High-affinity choline transporter BetT OS=Serinicoccus sp. CNJ-927 GN=BJF86_05925 PE=3 SV=1 -SSL---VGREASAVPWRLRLARTFGTVSVPQAQERMSGVVVP-ALESVRDALLeqgvqaevlVTevdpgarvvqtatlqvsgeseasgfsypvqirrtpaptfgtrsldaRDRTTRLQVA------------HPIAGGYD----LMGYDAEDV-----CHDVLDQYERWAVSsamvaE-----G- ->tr|A0A229GH17|A0A229GH17_9GAMM Choline transporter OS=Psychrobacter sp. DAB_AL32B GN=CAN34_08310 PE=4 SV=1 -IPPH-LLKPSA----WRERIDYMADQPTRDKVLSYIKETIMP-SMVEVSEKFTetgwtthvnYDainnravlelqrgdgvefwyevrlsehdtpdyytEEGADKLPQQH---DHRAEVYLRRGGQTYD----LYGYESESV-----INDIIDQFEKYLHFvnvspDILPWRM- ->tr|A0A238HDZ3|A0A238HDZ3_9NEIS Glycine betaine transporter OpuD OS=Kingella sp. CHUV31 GN=opuD PE=4 SV=1 -PSSS-MWTGEK----WRERLAHMLNQAEEKDILLFLKRTALP-AMYQLQNELIsnygfhaqvvKHfddevpavelvihketmrdfvygirsvakevaenlvad-EHLPNFQNAV---TYEPITYFSDGRQGYD----VGYMSQNEL-----IADILKQYERYLSLlgdvgQELMSHE- ->tr|A0A0X8X2E9|A0A0X8X2E9_9SPHI Uncharacterized protein OS=Mucilaginibacter gotjawali GN=MgSA37_02552 PE=4 SV=1 ---MRNIMLFIDDVAGAEALAKKALKIACQCKANLQLCNVAANMAHKkelvghngdddefletdkfglkadelGQQLQAIYYPEGTFIPAVEYCEISNFNPVIIKEMVVKHNIWLIIMDEKQLRHIKNQDTGNYALKEISSLNCPVLIMP-- ->tr|A0A1M6MTU0|A0A1M6MTU0_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter aquivivus GN=SAMN04488007_1749 PE=3 SV=1 --DFEQVVLPIDFEItYDDTTLFKISNYITSKSTHINLLYVTKsKIPLLEEIEVLQKQFAKRlslkiPNNVSFHRVVSKKIEHGIQSFSKSINADLIIMISKDYNLLQKIFLDTTVEEVSFKTSIPLLSLQG- ->tr|A0A1T4ZUU3|A0A1T4ZUU3_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter arcticus GN=SAMN05660866_00296 PE=3 SV=1 --GFKQVILPVDFEMaYDDATLNKIANYITSDKAHINLLYVTKsPIPLLEEIEVLQKHLAQRlseklMNTVSFHRVVSRKVEDGVHSFAEGLNANFIIMISKDYNLFQKLFLDTTVEEVSFDTSIPLLSLQG- ->tr|A0A1H4R6P1|A0A1H4R6P1_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter dokdonensis GN=SAMN05192540_2776 PE=3 SV=1 --KPSKIGFPTDYNIfYTYPILKSLTEVLQISNATLDVVHVTQaKTNFSNTQIANKAYLHDYlkemfTGFHCFKEIQGLNIKETITTYLTDNSVEMLTMAAKNINLFQQLFFNPSKSQLNHQSSVPLLVLHE- ->tr|A0A1W6MPI9|A0A1W6MPI9_9FLAO Uncharacterized protein OS=Nonlabens spongiae GN=BST97_13785 PE=4 SV=1 --DTHEVVLTTDYKLkYHKNQIEQFKQVIHFLQGHLCILHVAEEKELNTSESKNREWLEGQfqGIPHTFHHVTGHDVKEGVRHFIESRDSSMLAFGNRKHSFLSKLFSTNMAMEFGMFSDIPLFVMSG- ->tr|K6GS65|K6GS65_9DELT Universal stress family protein OS=Desulfovibrio magneticus str. Maddingley MBC34 GN=B193_1447 PE=4 SV=1 ---MERILVGIDASHPFWEALDRALCLGPRIQARVSVLVVFPPNEGqggeagQAILRRVESEIAAAATTgaTVELFVTEGRFDQAMVSAAGQLKTTLLVAAATGRDEQGGERETENLGRILAGVDCRVELVSPK ->tr|A0A0Q5ZJ20|A0A0Q5ZJ20_9BURK Uncharacterized protein OS=Ramlibacter sp. Leaf400 GN=ASG30_20520 PE=4 SV=1 -GLPRGILAVVDAGAGGTHAAWRAALVARDHGRPLHLVTIQprardala----AKPLLQDLAGQLEQRiQVRATTAVVAGALR-ECLVELAA--HRELVVVPWqRS----ASWSdkvLGTPPERMLRWLAAPLLIVR-- ->tr|A0A0S4PKT0|A0A0S4PKT0_9BACT Nucleotide-binding universal stress protein, UspA family OS=Armatimonadetes bacterium DC GN=DCOP10_116128 PE=4 SV=1 ---PTHLLVPFANTPEDRELLRHAVRMAQVFEAHLTVLCFVEVSRGvnleqcppekmrrgEEFALEAREIIEELGFGNYTIQTRpTHHCGFAIVEAVREYGCDMVCIAAEYRRVLGRQLLTETVETVLRKVPVQVCL---- ->tr|T2KLA5|T2KLA5_9FLAO Universal stress protein, UspA family OS=Formosa agariphila KMM 3901 GN=BN863_15110 PE=4 SV=1 -KNFKEIGISTDFDISfTEKGLSPLLDIATSQKATVSICHVMDRAKKLTSSQNEKKEALKVmlKDCSAGYFTLTGIGVsTGIRAFVQSRKLDMLCVIAKEQDFLKRLLNQSYSKSITHRANVPLLILN-- ->tr|M7MDU6|M7MDU6_9FLAO Putative universal stress protein UspA OS=Xanthomarina gelatinilytica GN=D778_00795 PE=3 SV=1 -MDLSEIGFATDLSIEnYGDDLDLLKEIAMAHNAIISAVHITNKSTNLSPDLLANKLALEMtlKPIKMDFYLINDVPVeVGTRVFSESRKLGMLCIINKKRSFFEKLFNRSNSKSISSHLNVPLIIFN-- ->tr|A0A1V3WTJ2|A0A1V3WTJ2_MYCKA Universal stress protein OS=Mycobacterium kansasii GN=BZL30_6625 PE=3 SV=1 ------VLVGIDGSPASERATAIAFEEASWRGAELVALHAWTDAEvpgtpsrewtgltrtsWSTLQSEADETLAErlagwrdrYPDVDVERVVVVNRPRSTSSSARN--QRSWWSSEATGVVA--------------------------- ->tr|A0A1Y6BSI5|A0A1Y6BSI5_9PROT Nucleotide-binding universal stress protein, UspA family OS=Pseudobacteriovorax antillogorgiicola GN=SAMN06296036_108126 PE=4 SV=1 ----KSILLGLSLYEDETHLVRFTQSLCQSLRAKLLLTHILKPFHYYayageapvfpldtygpimdeldeENAQKLLSKIQEGLDVESDIIVKRDSLIEGIEEVAEKGKAGLIVLGSNYSNSVWQGLSTSIS--LMRGSSFPVLVVPQG ->tr|S3VE70|S3VE70_9LEPT Transporter, CPA2 family OS=Leptospira fainei serovar Hurstbridge str. BUT 6 GN=LEP1GSC058_1872 PE=4 SV=1 -----GILVAFALHSRGIDLLRLANGLfpAGNKAKEVTALHMSPDSSIsgkvaqryeKTSFEPLHKLSKELGLKLKTLYKPSDNVAKDILRTIQSGNYNMFLTGGAR-SLFSDDVLGGKIRTLLSESNGNA------ ->tr|A0A1M3E4N7|A0A1M3E4N7_9BACT Cation/H(+) antiporter OS=Bacteroidetes bacterium 43-16 GN=BGO31_05365 PE=4 SV=1 -----KVLYAFDEPEAGRQLVKIGAAIfnG--AETQYTAAHFAEAEDMhlydiaayeNKVFQPAVQVAKKQDLSLKTHFAAAGDVDTALIEKTHKGKYDMLLMECSP-SIYDGTALGkilgftsriinldklyrsiarkaevaswnvidESISSIADRLNIDF------ ->tr|D3DIU8|D3DIU8_HYDTT Putative uncharacterized protein OS=Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) GN=HTH_1297 PE=4 SV=1 -PQISSLCIPVDFSERTLKQWNFLEYLKEHFSLNFRLVYALNVARLKnklsseeyqkllkDKKDEAVHLLKEmFGDKQLELDLLEEDPYNGLSKHINSGDYNLLLISKRGKGMAK--FVGSVSQHLTRTVRCPLIVL--- ->sp|P36204|PGKT_THEMA Bifunctional PGK/TIM OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) GN=pgk/tpi PE=1 SV=4 ----GNWKMHKTISEAKKFVSLLVNELHDVKEFEIVVCPPFTALSEVGEILSGRNI--KLGAQNVFYEDQGAFTGEISPLMLQEIGVEYVIVGHSERRRIFKEDDEFINRKVKAVLEkgmTPILCVGET ->tr|A0A1Q9P009|A0A1Q9P009_9ARCH Inner membrane transport protein YbaT OS=Candidatus Heimdallarchaeota archaeon LC_3 GN=ybaT PE=4 SV=1 --DMDNILVPVSGKSYETQNLLVTAYLARKYRVKITLLHIAKNGKIgknkknGKAFKTAESIFKEFKV-EYDTVTRPGnHVDRQIVDVYKNGNYQLISLSSRRKHGFfTRMFEKSISANVVKNVSCSVLQVHPP ->tr|G6F1J7|G6F1J7_9PROT Uncharacterized protein OS=Commensalibacter intestini A911 GN=CIN_14930 PE=4 SV=1 -KTPQNSMLAFSGSEISKRLVKHLAQEKYCLSIPLYLVMSGKPTNErQKELDWAHQILENAGYNVISSFILgGGTIEDTIIRTVQEQCIDILFMSAFENNSLYNLIFGSKTVDLLRYLNIPIL----- ->tr|D7VZW6|D7VZW6_9FLAO Uncharacterized protein OS=Chryseobacterium gleum ATCC 35910 GN=HMPREF0204_12965 PE=4 SV=1 -----KILLPVDFYSTSDNTFLYAIAFAEQFNADVHILTVLEDTAEPEQNNQFRKGLKEREIelfyqqiksykntseVNLSFGLTKESFTDAIINYLQNNAIDFLIIGYDTNGIKSNSQIRQEISEKNYKVNVPIIIVP-- ->tr|Q3SFP5|Q3SFP5_THIDA Uncharacterized protein OS=Thiobacillus denitrificans (strain ATCC 25259) GN=Tbd_2608 PE=4 SV=1 -RPYRRVLALIGFDADDALVARKAAAFANLNGAELDFLHLIAPDAVldggyaggspaatasaleQAALRRLQFLAAQCGAGEARCHAVHGPRRQRFTDHLAAREAGLVVTT--------------------------------- ->tr|A0A1M6NIN1|A0A1M6NIN1_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Maribacter aquivivus GN=SAMN04488007_2069 PE=4 SV=1 -NHPKEIVLTTNFNTKiKSSEIKYLVEIAKLSNANIQVLSLTQPNKLSFSQKRNKVFIRSQlkGVEYKFNTLRNVKMAIALSCFVEIRASNMISYVDKKPSFWERLgFGKLSLSKLGYYANVPVLALHA- ->tr|A0A1G7E1A4|A0A1G7E1A4_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Cellulophaga baltica GN=SAMN04487992_1029 PE=4 SV=1 -NQPEEIVLATNFNTDfDISEIKYLVEIAKMSNARIQILSLTDDSVMTAQQKNNKSLLEKYlvGLDYIFNVLHNVKMSAALSCFVEIKHSNMISYVDKKPSVWETLgFVRPSLGKLGYFNDVPVLALHG- ->tr|A0A1M6GC06|A0A1M6GC06_9FLAO Nucleotide-binding universal stress protein, UspA family OS=Pseudozobellia thermophila GN=SAMN04488513_102756 PE=3 SV=1 -TDLKKLVFATDFKHAfSPIELLPLIDIAKLWNATLNVVHIKTEESLSEEQETNKAILRNVlkGSKHLFFEIKQRdSVANTLIEIEKtNKSMGMMALLMTDHGFFQKLVRPNIIKSVAFKTEKPLIVLPQ- ->tr|A0A068U895|A0A068U895_COFCA Uncharacterized protein OS=Coffea canephora GN=GSCOC_T00017969001 PE=4 SV=1 ----AVYYVALVqGGqqgnggskraadqdSASMDALLWTLNHAATanndptTTPLLFLVHVFPEIKHiptplgmmplsqvnpeqkeiymaqergkrTQFLDKFLNACSSaAEVKVDTILIESDMEAKAILDLIPILNIRKLVLGTTKAilRKVRSKRSASgVIDQIVKGAPefCEVKVI--- ->tr|A0A1U8GL57|A0A1U8GL57_CAPAN U-box domain-containing protein 36-like isoform X2 OS=Capsicum annuum GN=LOC107870100 PE=4 SV=1 ----DVVYVVVWnKInnvsdheGPSMDALLWTLNHVVInqNSTNVFLIHIFPQTNFiptpwqvneehkekymtqerskrRQFLQKFVDICSSSKVKVDTILIESDMEAKAILNLIPICNVRKLILGTTKAnlKRMKSRKGNGTTDEILQNAPefCEVKII--- ->tr|A0A106BSS6|A0A106BSS6_THIDE Uncharacterized protein OS=Thiobacillus denitrificans GN=ABW22_03485 PE=4 SV=1 -KTYRRILVPIPANGQGDILLQRAAELAQGPRTQMLVVRVLDTRSGFepdgpaavlpgeaaarrapDVKKRLELQLARNNLGWAEAKVVWGETKVLLADVIRTWEPDLVV----------------------------------- ->tr|A0A090P451|A0A090P451_9VIBR Universal stress protein E OS=Vibrio ponticus GN=JCM19238_811 PE=4 SV=1 -SIYNNILVVANINSDEQPALARAMQLAAksRSRSHVTFFLSIYDFSYDmtsmlsidernamrkgvihqreQWMRSVAEPYLNDSIDFDVVVVWHNRPYEAVIAQVFAGEHDIVIKGTRKHDVLESVIFTPTDWHLLRKCLRLF------ ->tr|A0A1M5WAZ9|A0A1M5WAZ9_9BRAD Nucleotide-binding universal stress protein, UspA family OS=Bradyrhizobium erythrophlei GN=SAMN05443248_6457 PE=4 SV=1 -MTYATVMVSLALDRSNDTRLEIAGQLAKRFNVVEIAEDDVHRPAELSGVNDVVAWLSRHGVVaSGQAPSECGDVPTQLDRIASELGAGLIIAGAYGHSRLREWVFGGVTKGLVNPSGRCTLLSR-- ->tr|A4A1T6|A4A1T6_9PLAN Uncharacterized protein OS=Blastopirellula marina DSM 3645 GN=DSM3645_29491 PE=4 SV=1 --ELDRVLLIYDGSNASSRSIRSFLsQHAAYLGNQYRLLCVGEAASPQSGAYRAMLQYCRSRMETLEVGCLPGSPVKTAAKYAQKWEADLLVLGVARTSSWWGSPFGQLGSDILQHTELAI------ ->tr|A0A1P8F7Q6|A0A1P8F7Q6_9CHLR Universal stress protein family protein OS=Dehalogenimonas formicexedens GN=Dform_01176 PE=4 SV=1 ---IKRILVPLDGTPYAQQILSVARRIGENFKADIVLFSAVKSAGRtaadiENQKKEASKYLDGvaamlYGLNVTTIISEANDFTTAIDWAAFQTKSDMVTMVTN--SRVTEWAENSISRKILNTGATSMLIVHR- ->tr|A0A0S7YWS3|A0A0S7YWS3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium SG8_13 GN=AMJ54_03420 PE=4 SV=1 --PDSRYVVCADGSPSAQRQFPLLKGLLHSIRGPVDLVWVKKPDvkkqdieAAEKCLQHAWNWLETCDRAGAVHRLEGENLVDLIVDAAG--TSSVIVMGASLRHDVYRRMLGSLPMQVLSKTKSSILLAK-- ->tr|K1ZU53|K1ZU53_9ZZZZ UspA protein OS=groundwater metagenome GN=ACD_73C00798G0007 PE=4 SV=1 --GIKNVLVLVDEFPFSLDAIKQGVQFAADLRATLYFFHLNDPSGEtlnsFESIKQSLQIPPHQGGD--QWLIEEGDFFEMIDQVIAEHQIDLVVFGTHINADHPE--SGQRTLAIINKIAIPCLILHPH ->tr|A0A1Q9D3B5|A0A1Q9D3B5_SYMMI Uncharacterized protein OS=Symbiodinium microadriaticum GN=AK812_SmicGene28871 PE=4 SV=1 -----RVLVSVDGSDQSSCAFEWVLHGFTQSDREtdLLIVHYYDDTKEYlppkwrrnAIQADAEAKCTSYLVSkRYAISVRQRSPGVKIgvllCQDIKDQGTSFCVMGFAGRKGKDRHIIGSNVLEVMQRGKCSCVVFKEA ->tr|A0A0M9E149|A0A0M9E149_9DELT UspA domain protein OS=Candidatus Magnetomorum sp. HK-1 GN=MHK_007849 PE=4 SV=1 ---MKKVLLAINGVTPSTKIFHYALQLCQRTTATLVVLQIIGKRHASgyfdkirkkagavkqffensmiaatyaeagehdialeliglakKNIQKMLQECRNAGV-SYQLVFKKGEPEKEIINYVCqNRDVIFTIYDSPIIQQADKDqlkERKRQMSIMEKNLPTPLFVCNDE ->tr|A0A1J4V530|A0A1J4V530_9BACT Uncharacterized protein OS=Nitrospirae bacterium CG1_02_44_142 GN=AUJ60_02095 PE=4 SV=1 ---KEKLLFVTKGGEDCDKGFSYVLELAKSLNAGIELLMIYGKGVLDkyedvmaavafaeagdhetvrelmnaqgkkikdtaeKKINELTEKCRDANI-DFSSEVKTGEAIEVVKDFIKnKPCIDMILLSPNLSGD----KKLLDVRKMLKNITKPIVTMMAA ->tr|A0A1V5G2H5|A0A1V5G2H5_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.BinA261 GN=BWZ06_01223 PE=4 SV=1 -SEMNKIAFLTNFREREFVAFERLMKLIGDRQIEVYILHISKKDDLWNeiKLSGMKNYLKEKyPLLEIHYKLLDsanDRLEVAIDNFVKENQIDMISMSSSRRNIFARMFNPGLARRVIFHSKTPLLVLKN- ->tr|A1SI72|A1SI72_NOCSJ UspA domain protein OS=Nocardioides sp. (strain ATCC BAA-499 / JS614) GN=Noca_1997 PE=4 SV=1 ------VVVLCDGSPESQSILAYAWGQADRRGLPLTVVHCLPDPPADlhprdislmdatarmeaslgpsllgferLLLSDLVRDMRSRWPGVDVRLVVEDDAIDRWLERAR-QQADLLVVGARHARRLSELVIGSSTPEE---VECVTVVLPL- ->tr|R7B8B9|R7B8B9_9CLOT UspA domain-containing protein OS=Clostridium sp. CAG:505 GN=BN684_01391 PE=4 SV=1 -TKKENILVLVTAGKESKRFMELAKDAAEAGNGDLYILHVaqgeniLESGEMY-EMQRLADYGCRLGG--QVCLCCEQDVAAYISRFAREKDITGVLLE--------------------------------- ->tr|A0A142HW04|A0A142HW04_9SPHI Uncharacterized protein OS=Mucilaginibacter sp. PAMC 26640 GN=A0256_17385 PE=4 SV=1 ---ATNILIPTDFSLTSLKVIPALLQQQPAQQFNIVLVNFLGlsdsitdllmlsrrsrereliTQEFMDECTKLSRQYADQIL-CLQTEFFYGTTIAVFKNYLEAREITQIAKLNNYKIEKLTT-LSYDPDLLLERSKYKVVSLAP- ->tr|A0A0D0GHB1|A0A0D0GHB1_9SPHI Contig57, whole genome shotgun sequence OS=Pedobacter sp. NL19 GN=TH53_13420 PE=4 SV=1 ---MKTILIPTDFNEASVYLSENILKNFKNESVKIIFFHAYKltdsisdllmlsrrsteygqiPESFHRACYDFKKTHQGKIA-AIGIEYFYGSTMAAFRNFAEAHEVDFIYCPEAYSFRQISK-YSINPDVFLNKSGIPVINTVM- ->tr|A0A1G3XV10|A0A1G3XV10_9ARCH Uncharacterized protein OS=Thaumarchaeota archaeon RBG_16_49_8 GN=A3K61_03070 PE=4 SV=1 -----PIMLPLAFESREWNTVHIALFLAEYSGSQVNILHVNSRIDNTEKRDEFLKKLKSIAAelkikysvnyaKAKSAEPGVSEIADTIVSQSEKMGCQAIVMSANRESFFRE-FFGRISDKVARKSKRTVLLV--- ->tr|A0A0C1TPY1|A0A0C1TPY1_9CYAN Uncharacterized protein (Fragment) OS=Aphanocapsa montana BDHKU210001 GN=QP59_12135 PE=3 SV=1 --EIDDIAFAVNYQDEEVEAFQKVVDICRPFNAKIHCVNVdlSHTEDYRKEMDQFKEKLVAYDN-TTFEVIESTDIREGLTKYMETHSVDVLVMVTHKRNFFQELLRYSHAKEMSYHCNMPLLSIPSH ->tr|A0A0M0KBY3|A0A0M0KBY3_9EUKA Uncharacterized protein OS=Chrysochromulina sp. CCMP291 GN=Ctob_011840 PE=4 SV=1 ---PKKFVVAIDGSKLGFRAAKLAACFCDvRAGDKVKMVIVrtgkLDATQANALLKNAETMLKEGCFPQMNIdraevlEIQTGkSLAETLCSAAAADKGGMLVMGAGGMRLEEEWklkkkttpaaMTGSVALECMAKCKVPVIITKP- ->tr|A0A1G0AHB1|A0A1G0AHB1_9EURY Uncharacterized protein OS=Euryarchaeota archaeon RBG_19FT_COMBO_69_17 GN=A3K59_06350 PE=4 SV=1 -TPLQRLVVLTSPIWPLSGIDELALILAEEDHPAIEVLGLAGDPAEAERLKQEAESFLAeghaRGHSIEHRILYSRQWESVALQESA--EASVLLVRASSPGGLRKFALGPVEDRIVKLARCPVLLLR-- ->tr|A0A1F9Z760|A0A1F9Z760_9EURY Uncharacterized protein OS=Euryarchaeota archaeon RBG_16_67_27 GN=A3K66_00595 PE=4 SV=1 -ERPERILVMNAPEWHVSYATGYAILLAKKHKARITVFTAAQTDTEMAKETAYSARLAEmcrtHGVAFEEKFLKTRSIADAVVAEAA--TYDLVVLGASSEWRLTQFAFGPMQDQIARRIAAPTLMVR-- ->tr|A0A1F9Z5N0|A0A1F9Z5N0_9EURY Uncharacterized protein OS=Euryarchaeota archaeon RBG_16_67_27 GN=A3K66_07650 PE=4 SV=1 -RPLKKLVILTSPIWSILGIDELALVLAESDLPTIEIVSLAADPSDAERIKKEVAPFLEtchsRGIAVEHKVLYSTQWESVALHEGA--DASALLIRASSPGGLKKFTLNPVEDRIVKLAPCPVLILK-- ->tr|A0A0S2KBJ6|A0A0S2KBJ6_9GAMM Uncharacterized protein OS=Pseudohongiella spirulinae GN=PS2015_811 PE=3 SV=1 -NKMDRILVIVDPDNDKDFVIERAILLAFYYRAQVLLLmnkpNVLDQQDaatssltsrffssqkklfaehYQAKLDALKERFEAQGISAETQFSTDKNSAAMLLRKIREFKPDITLKSVQQQGRLARILITNTDWKLVKNCPYPLLLVKA- ->tr|R5AQ38|R5AQ38_9BACT Uncharacterized protein OS=Prevotella sp. CAG:1031 GN=BN456_01294 PE=4 SV=1 --HPPRTLITVANPITAPSLVELAMMIHQgGKSTPDSPIYALYvrGSDHSDasraigrnALSVAEKAAAAVDSTLIPIERYDVSITAGVLNTVAERDISEIIIGLHGRTRITDSFFGQKIEQLVRSTNRMIVVSR-- ->tr|A0A0E9ED82|A0A0E9ED82_CHLTH Uncharacterized protein OS=Chlamydia trachomatis GN=ERS095036_03343 PE=4 SV=1 --DDEHILVPIKYPNYAEQLIGLAILMKSrKLNRPLTAINVVYEDEQMRvnqekgkhLLEQVTRYAAGSDVQVQSQVRIAVNIANGIKHAFQEFHANEIIIGMHTHAEVSKKFWGQFHQSLFNGLNCQIIMAR-- ->tr|A0A1D8MY72|A0A1D8MY72_9GAMM Universal stress protein UspA OS=Edwardsiella hoshinae GN=A9798_08235 PE=4 SV=1 --MYSNIMILLDLkaaSQADAQLLDKGMQLADRFDASVHPVHVVldiepgengNQSLYFKQLEEQANNLQHARGAacPEIAIIISNDFSSSLQDFIRQKKIDLIILGHHNSAFAQKFVsFLSVAKNTIDTINIDTLIVPLS ->tr|A0A0F2NK40|A0A0F2NK40_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium BRH_c16a GN=VR65_08735 PE=4 SV=1 -AERQRVLFYNDGSSLSLGTAKWFVGKHNLSKMSIVLLMVATQDREEMLADTMADKqqrereqarkqsfidirqvlieggIPEKNIETVVTTVNEKVPIsDKIIEYLSEHEFDFLLLCKHNKRKSEEFLFGDTAIQVLRKTTTPLLIVKGT ->tr|A0A1E5HB21|A0A1E5HB21_9ENTE Uncharacterized protein OS=Enterococcus ureilyticus GN=BCR24_03195 PE=4 SV=1 --MYKKIVTVVDVFGEPNGVLAEVITMSQRENSELHLLINKPEIEaleqlnylpydsgmympyeydmikendenYQKDVDKVISKVKAEGVDKLVTTIYSGSTKSFINKYIEKNSMDLIVLGSYD-ELLSKRELESVAKHVIKNTTSNLLILR-- ->tr|C5X6K0|C5X6K0_SORBI Uncharacterized protein OS=Sorghum bicolor GN=SORBI_3002G136800 PE=4 SV=1 ---GGKLYVAVGKDrKDGKSNVSAAqSLGLVGGDLKLVLLHVHQPADRImnglgckvlasqleekelkayrqieqeemdRLLNTYVNHCRSyLKVEAETLIIEKNNVANGIVELINQHRITKLVMGMSSFSTKRKVPKSKVAAIVHQQAKpyCQIFFI--- ->tr|A0A136K239|A0A136K239_9BACT Uspa domain-containing protein OS=Chlorobi bacterium OLB4 GN=UZ04_CHB001001429 PE=3 SV=1 --DIRKIVFYSDYSDNELNDLAKLSAIFVKFQPKIVCVIFKETRQElesETIYNIENQIRRANDDCEFEIKkIVTDDEIESLNTIAQYDSADIIAITTHQRNLIDTFFNPSKAKQLSFNSFIPLLAMS-- ->tr|A3QEY7|A3QEY7_SHELP Uncharacterized protein OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=Shew_2169 PE=4 SV=1 --SYQRLLVVVDEHDFSLKAVSRAVYLASKTHAAIIVMMLEHSHFVNRLVDtfeadgnegqtqpltkerklsclnAFISQAAQSGL-SISKASIACHSSDDVLQFCDDFKVDAVILAASRHKLWNWLTIKPLDVRLIRESSRPVVVVKDH ->tr|A0A1T5B637|A0A1T5B637_9BACT Nucleotide-binding universal stress protein, UspA family OS=Dyadobacter psychrophilus GN=SAMN05660293_00041 PE=3 SV=1 -SGFKNIIYATQFDPQETDILHQIKVLTEQLGAKLILVKVnsFHEPESHANQAHMFRTIQELDMADVDVVIVEDvSFIEGINKFCDRQGADLLIVSNRERHFLQQYLTNpSMTKRLVVETHLPLLVYH-- ->tr|A0A1A9I3M8|A0A1A9I3M8_9BACT Uncharacterized protein OS=Niabella ginsenosidivorans GN=A8C56_09440 PE=4 SV=1 ---FYKILFPVRDVEGVKEKLVHSRPFIQKDNSELHIVCLGQPDSYKVNEVIELAQNQQIQFSISDFDADSKkNIAPGVILAAKERQADMIVINATSEKQWYNIFGENYTEYILKEAAMAVLSITH- ->tr|A0A1W9V7M3|A0A1W9V7M3_9CHLR Uncharacterized protein OS=Anaerolineaceae bacterium 4572_5.2 GN=B6243_07990 PE=4 SV=1 -GSPQRILIPVAGGPNAIQAVEIAHRLN--PQAEITLLFVAT-RHLEAEIDVGRKRLSAVsdffpDIKTIHEVVVADNPIKGILREAKD-GYNLLIIGaSAEKNIFDRFIFGNIPKAIFHRSPIPTIILR-- ->tr|A0A0H3I9E4|A0A0H3I9E4_PECSS Universal stress protein A OS=Pectobacterium sp. (strain SCC3193) GN=W5S_3461 PE=4 SV=1 -KIYTHALVLVQGKEDGVPLLALAATLSRLLQMKITLAHICNDYREMnyisdglmddavskdvvQVKALFSELASSVTEHVDARELVTMRRFEEVQKCITDTGVDLVIAGHRNRFMG---ALTSRSAEYVNHLNVDVLI---- ->tr|Q1JZA5|Q1JZA5_DESAC Uncharacterized protein OS=Desulfuromonas acetoxidans DSM 684 GN=Dace_1524 PE=4 SV=1 -MDCQTIVVNYTHPDRDAEALSTALELAYRHESELLLLHSNGACckeacqrnylFSEEELVQQVNKANGYGVPVVVKIVDEQSPLEEAIRHLD--NHDLLVVGDSHADCFSNRVNNVSASRV-------------- ->tr|A0A200PPS5|A0A200PPS5_9MAGN UspA OS=Macleaya cordata GN=BVC80_23g8 PE=4 SV=1 ------IVVAFDDTAESMVALEHVLNFSAKKPFNKIVIALIQSPEQgsvaceeEVLTQKAKELCISKSVKDmPHFEVVNGDTMTVLCEIAKKHRARVLAVGGHY-GGLAAGSGDLEGVALVNAAPCNVMIVPRN ->tr|A0A1W9UDQ5|A0A1W9UDQ5_9CHLR Uncharacterized protein (Fragment) OS=Anaerolineaceae bacterium 4572_32.2 GN=B6I35_11675 PE=4 SV=1 --MFADLVVAINGAEAGWRALEHALFVAQHEGARVHGLHVAASETQREskdtqtIRVEFDRRCQEADV-PGELAVEVGKVPRSVCWRAR--WADLVILSLSYPPAARPiARLGSGLSAIIRCSPRPVLMVPET ->tr|I4VI44|I4VI44_9GAMM Uncharacterized protein OS=Rhodanobacter sp. 115 GN=UU5_20800 PE=4 SV=1 -TRPNDVLALVTSTDPWGPSVDAAIALAARWAANLTGCYIDPSLRHAaepdreapglpqlhdmdhAEHAAFASHAHDLGVRDARWTVTRRNIPLTLRTLGA--WHDLVVVEHDIVAGDQL---LDILGEAMLTSRMPCLLLPPG ->tr|A0A137P2I4|A0A137P2I4_CONC2 Uncharacterized protein OS=Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638) GN=CONCODRAFT_71613 PE=4 SV=1 -SRKRKILFVYEEPTDSRQSFEWCESNLFRPGQDYVCLFAIDPNAnkfmdtslfwtaaaedyevedserdkikkenfVEKELEAIKIKLSAKNIPCQKLQSLNGDPKTLILKQAENMLADLIVVPPSHPNYFSKTVFGTLEDYIVKNSLCTVVV---- ->tr|A0A1F3SY20|A0A1F3SY20_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium RBG_16_40_8 GN=A2Z20_08710 PE=3 SV=1 -SEIKNIMYATDGSDESFYAFLKLVVLAARLKCSITLLTILPTPTRWarpyvrfnsvrytkmvlkKFSTWILKAKKKGVIAYVEVVRSEENVVQAIVGVAHK-KTDIIALSARSTAAPLATIMG-VSHKLVYLAKEPVLILKS- ->tr|M0MK22|M0MK22_9EURY Universal stress protein OS=Halococcus saccharolyticus DSM 5350 GN=C449_04807 PE=4 SV=1 --------MAYATGSVRrfgacEDGAGSRPRVRGRTNEDLLTLIVVPPDEVFARNRGWITSDEAFDPERVGSELetavnevapdvtvrieateemsslasTEMDISRTIRQVAHEIDASVVFVGSENAGRVTSP-VTSVGTPVSKDPGYDVYIVRHA ->tr|A0A0L0HMK6|A0A0L0HMK6_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_01737 PE=4 SV=1 ----RKILYCLDDTEADYNHLEWVLKHYLHSNDELTAVNVRHTPmptgrsldawaeykhaekdkAYKDIQVKLQQVCSKAGKSfPLTVIVEcEEKAGKYLVNLANDTKPDVILVGSLERKGIiSRLFHTGVGHYVAKHASMPVVAVKD- ->tr|A0A136P710|A0A136P710_9BACT Universal stress protein family protein (Fragment) OS=Chlorobi bacterium OLB7 GN=UZ07_CHB004002570 PE=4 SV=1 ----MNVLLAFDGSKSSVAALHDLATAGLDADTRFLVVTVAEVWHPLepesleqeplpefiptglrslherssrelsrafQIADEGADLLRNsFPAATINAQAYADSPSLGILAQAEEWRAEMIVVGAQGRSMLGAIAAGKRLAQSVGRGALP------- ->tr|A8TY69|A8TY69_9PROT Transposase Tn3 OS=alpha proteobacterium BAL199 GN=BAL199_22817 PE=4 SV=1 ----EEVVIGLDGSLAASNAFKSYVRMGLWARARLHFVHAVEDHWPdreaaiSSMMDDALAYAHRFGR-RAVAHVMAGSTLDAMNRIIQETGATAAVLGSNRRRLFADRRLTATTKKLIRDNGMSVLIV--- ->tr|W5W9K7|W5W9K7_9PSEU Uncharacterized protein OS=Kutzneria albida DSM 43870 GN=KALB_3847 PE=4 SV=1 ----QPLLVGTDGTASSEPALEWAFAAADCIGCGVRVVFSPAAATEsaklrESMLTTVTALTAHHRALDVRLHSRDSSLLEALSWHSQ--SASMTVLGPRNGTVTAA------TERVLLRSNCAIVLVPQ- ->tr|A0A150G9H7|A0A150G9H7_GONPE Uncharacterized protein OS=Gonium pectorale GN=GPECTOR_46g284 PE=4 SV=1 --PQNVIVVAVTDDPASTLAVRTAMAIMKPGADCLHVLTIAKDISAtaQAVARNVAERYESmasatLGDVRSIVQVKQKSIVEDILEYIESVRAMLVITGSMSLAAVQTSVVGSVALSLARDCTRPILVVKSN ->tr|A0A1J5BBC1|A0A1J5BBC1_9BACT Uncharacterized protein OS=Armatimonadetes bacterium CG2_30_66_41 GN=AUJ96_11135 PE=4 SV=1 -FPFKRLLVPVAGPVNVELIADIVPALKRAGEAFVTFMQMAPPEADQAAARELLRALLAEHNLAEAGELVvraTENVQRALVRESA--KYDLTVVGAPRQHLFAR-IFGDVAERVARESDKSVMIIRG- ->tr|I0I8Y9|I0I8Y9_CALAS Putative universal stress protein OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=CLDAP_36870 PE=3 SV=1 -----RMVAATDGVVFGQRAVKLASELQPLLVGDLTVVVIASEREGAERAQQVMVETAAmlATEPKPELVPLVGYPDEVLLKYLETHPTDLLIIGAFADRGAGGvSAVGPTAHRIVQEAPTSVLLVKGH ->tr|A0A1B2E036|A0A1B2E036_9BACL Histidine kinase OS=Paenibacillus ihbetae GN=BBD41_12445 PE=4 SV=1 ------IYVLVGSGPESERIIRRGFRIAYRLKAAWYVTPLPDRA--edcKPSMPAR-DPIQAMterlgGIFRPLELLgkRVYDLPAILIAAADEVKATQLIIAQPPGNGFPGASQMRFAKQLLRRARhMDVLVI--- ->tr|A0A077KJ32|A0A077KJ32_9FLAO Putative universal stress protein OS=Chryseobacterium sp. StRB126 GN=CHSO_2369 PE=4 SV=1 -NSIHNIVIPCDINGiKKLERLFHHKSIIQKHDVHLSFLNINTKEKTEInsDKKKELEDYIRQHLTEIPSSIHysyDENVINGILTFAASNNTDLIIALPGKHSFLYYMASRSISEGLYQNTNLPVLILK-- ->tr|D7W1U3|D7W1U3_9FLAO Universal stress family protein OS=Chryseobacterium gleum ATCC 35910 GN=HMPREF0204_13373 PE=4 SV=1 -TPVKNIFIPCDINGiKRLERLFHHKSLIHKQDVHLSFLNINTREKEDENKKKELEDYIREHLTEIPSSIYyshDENVINGILTFAATHEADLIIALPGKHSFLYYLASRSISEGIYQNTHQPVLILK-- ->tr|A0A0Q5U1S4|A0A0Q5U1S4_9SPHI Uncharacterized protein OS=Pedobacter sp. Leaf194 GN=ASG14_12280 PE=3 SV=1 -QPITHAVVSFDEHSsTEIYYLNRLKHLQNNKNPTP-FEREKPGyhPEDIVpeSH---NYTLLNSILRSFRYYVYeqgTYDQPIGLSKFADSYYSQLIIAMPGNKGFFYNLTHKDISEKLVMDGHKPVLVLP-- ->tr|A0A061PD46|A0A061PD46_9BACL Uncharacterized protein OS=Geomicrobium sp. JCM 19039 GN=JCM19039_2592 PE=4 SV=1 -TDTDPVLIFLDFHEEALSCVTKGATIAEAEGRDIVLLHGIDMRKYTvverndptlrtqiisertEWLKTFEHQLRQNGQHVRATDLTFKDPRKIISAR----YAPFIVVALKRVHRSAK-IQKSLSDVLIDRPPCDMLIVH-- ->tr|A0A061NPG0|A0A061NPG0_9BACL Uncharacterized protein OS=Geomicrobium sp. JCM 19038 GN=JCM19038_228 PE=4 SV=1 -MPNLPLIIYVDYGNHSFAAVKKGATIAKQRNKDVILAHSIDQRKDSvtdrndiqskqqliqqrtAWLNDYKAYLLDEGIEVINIDLTFDKPSKRINEL----NADLIVAVKT---DRWG-IVKHYSHDLFQNPPYTLLGVH-- ->tr|W8EYJ7|W8EYJ7_9BACT Uncharacterized protein OS=Hymenobacter swuensis DY53 GN=Hsw_1242 PE=4 SV=1 --------VLTDFSAAATNALHYAVVLGRHVGGQVRLWHVLPEAAGFdapyfgglrearpvaeaQYLLQELVKRVQQHL-PCSAALITEKPTQKLTALIGTGSGNVVVVGNGNPVKAMRHAGTSTALHLIKTLAQPLLVVPNT ->tr|A0A0W8EMD0|A0A0W8EMD0_9BACT Uncharacterized protein OS=Cytophagales bacterium MC1A GN=ASU33_19250 PE=4 SV=1 ---------MADFSGAAANALEYASFLARQLtarqlSVRLRVLSVAADLSTtqglSaaptlpplellNQRLALLERLQNASI-PYTHELLQQPVAECLPDMMSAALPTVFICGRTD---TTAPSAEQTLLHLIRLVTHPMLLVPEQ ->tr|A8HRL3|A8HRL3_CHLRE Predicted protein OS=Chlamydomonas reinhardtii GN=CHLREDRAFT_187858 PE=4 SV=1 --PARAVLLAVAMDEASLAAVNYAIHELYRKGDQFHLVHVARILSPSitihhqyhatynvpelgpgidqrAFLERLKEEIKDKFTNPMDALGIPHNlhlfldtdnapasaVCETVFKVADQVDAAMVVLAAHGKGeegsrdPLLGLYLGSVADFATRNSARPVLVVRS- ->tr|A0A0Q9Z8D5|A0A0Q9Z8D5_9FLAO Uncharacterized protein OS=Salegentibacter mishustinae GN=APR42_04570 PE=4 SV=1 ---KMEMVLATRFDKSfSIAEINFLIDMTKKFKASIRILYIQDTEDLSEEQENKKEELHEHfEKISHSFHTLTNiEVTKGIHSFIQSRNSDILVLNHKKRGFFRNLFSKSLLKELGKKPQIPIIFMPA- ->tr|A0A1V9ZR02|A0A1V9ZR02_9STRA Uncharacterized protein OS=Thraustotheca clavata GN=THRCLA_05962 PE=4 SV=1 -------------------------------------MQQQGYPQQYDQYGQPQ--------QQYSQpqqqyg-----QQQQY---GQPQ--------QQYGQQQQYGQPQQYDQQYAQQaqygqapqAAYgAPNQYGQGY ->tr|A0A0F0GY48|A0A0F0GY48_NOCAE Uncharacterized protein OS=Lechevalieria aerocolonigenes GN=UK23_17635 PE=4 SV=1 ---------------GGEGVLRRAITFCRVRQVTrLRVLTRPYNGAAGSLDATADLVHAACPGVIVELVRETRSVGEEVRLF----PSDLIVVSGREGAAAEG--LQPAAGAALRQARCPVLFSCS- ->tr|A0A151E1L9|A0A151E1L9_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon SM1-50 GN=AYK25_07180 PE=4 SV=1 --LFRSILVPISSEFYPPAVFQISAFLAKAFHSTVTSIYITEKRILDDfdrlsdahlsfyereeaqhnirskhlaqaeqiVFRDAKGFFKKREI-PLQTKYLEGEFSEVIKNEIETNHYDLIIMGYGRACLIDY--------RLIDEISLPIWIESGA ->tr|A0A1Q6DRV2|A0A1Q6DRV2_9EURY Nucleotide-binding protein UspA family OS=Candidatus Methanohalarchaeum thermophilum GN=BTN85_1755 PE=4 SV=1 -----KILVLLAYPEIQENLINFAKASANSYkESSIIGFNFINLPEQTpltrrdklnspkveipdkkiveiqkAILKIARDKITSDNFDFDSKAMAGRKFEKTVINYVKKQNIDQIYMGWDGERSQNKLIFGSKVDKILKYVPCKVNIIKPG ->tr|A0A1W9R852|A0A1W9R852_9BACT Uncharacterized protein OS=Candidatus Omnitrophica bacterium 4484_70.1 GN=B6D56_04375 PE=4 SV=1 ----KKILFLVFTVKAKDELIDKVLEFAERIGARIIALNVVDFGMIRhlsqklekreaevsvdleeegwMYLYYVEERAKDRGI-MINIVQEEGVVERELIKASEKFAVDLVVISREEHQGIAN--FNKFIESLLLRVKCPLLIL--- ->tr|E8RAY7|E8RAY7_DESPD Uncharacterized protein OS=Desulfobulbus propionicus (strain ATCC 33891 / DSM 2032 / 1pr3) GN=Despr_1476 PE=4 SV=1 -QDRPYILVVTRNGHLSEHVMDYALNVAHRLGYGIVTVHVDTLPFYkdsgrrcrlfaaamEESTALFRGKAKTKKV-AIEHLREEGKVGVVVSRLCHaKKRIEFVIIDKGIR-----------LGEVAKHSPVPVFPV--- ->tr|F2NHG3|F2NHG3_DESAR Uncharacterized protein OS=Desulfobacca acetoxidans (strain ATCC 700848 / DSM 11109 / ASRB2) GN=Desac_1218 PE=4 SV=1 -PHSRKILLVSDGEKFDRAATEYALNVAQRLNNDIIAMNVCPSlaPLKnrfspfrlsrqelfkrraASGFTDLQRQAAAKGV-QCWHLINFGELNQAVEELNQeVKRIEFVITGAETG-----------DEKGTEAVTLPMFLI--- ->tr|A0A1M7Y912|A0A1M7Y912_9DELT Uncharacterized protein OS=Desulfopila aestuarii DSM 18488 GN=SAMN02745220_02700 PE=4 SV=1 -GNRGCILVVTSQAHPAQHVMDYVISVADRLGSKIIMASVNPRPLLrensflsrtvrvavSPEADIFRAKAQGRGI-AYECIAESGKIDKVISRLCHiVKRVEFVVIDQGIR-----------MEEVAAGSPVPVFSV--- ->tr|A0A1J5R473|A0A1J5R473_9ZZZZ Universal stress protein family protein OS=mine drainage metagenome GN=GALL_273590 PE=4 SV=1 ---FKNILIPVNKGMDASVAVKKALELKDEKEQvRIHFLMYRNESFEYnflnffkkkkssgnssyntlfeTRFPSFKKEIEEQcdNCSLVIDTIPQKNITKGLIKYINENSIDLFLFCQKRATHGLGFSKKINFNKIARQSSCSVLSITPG ->tr|A0A0H3T1L7|A0A0H3T1L7_9GAMM Uncharacterized protein OS=Photobacterium kishitanii GN=UA38_06495 PE=4 SV=1 --MYKKVLYALDID--SKPYLLKAIALAEQLNAELFVGYATNIDDQLfsddayfghqlgddlvntekdELENKIKDLITGTSLNKDHVYIVSGPVGMAIERLATHLSVDLVVMANSHHYFS---FLSKNGFLIKLATRHDFLSFS-- ->tr|A0A1A7USV2|A0A1A7USV2_9VIBR Universal stress protein family protein OS=Vibrio mediterranei GN=VME0621_01253 PE=4 SV=1 --MSNPVIYALNLH--SPQSLKRAASIARRFEGPFYVCYVTDLEEELeddteyfgevdaqayvnkkhsELKAKIHAMIDKASLQCEDVYILNGPIALTINELAEKVSAQLIIVSKTHHKYL---KWADHQRDIESRSHCDVYVMN-- ->tr|A0A135I702|A0A135I702_9GAMM Uncharacterized protein OS=Enterovibrio coralii GN=ATN88_00150 PE=4 SV=1 --MYSKILYALDIN--SKPHLEKAIEISRQLNAELYIGFATYLGESYeedevyfgkltgdqivddkknALEEKIESLISGTDINKEQIYIVDGPVGKAIDKLATSLNVELVMVAKSHHHFS---LMMKNDTLIRLTTHYDFLSFS-- ->tr|O28746|O28746_ARCFU Uncharacterized protein OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) GN=AF_1526 PE ---MERILLVLDDTGRGEIAFQKLKKLAEdGLRGEVYILYIREMEVPPfvpeekelaayhrlmtqsmKKLEGFKNQLEKAGLKVSDVSVVFGKYADRLLLVEKQIKPDLIVVGFKGGllkRVIGGFFGKDPCEVLLKKSKASLLICRG- ->tr|A0A0S2SFZ3|A0A0S2SFZ3_9GAMM Uncharacterized protein OS=Aeromonas schubertii GN=ATO46_02520 PE=4 SV=1 --MKNGIVLLLEGKAYERETLAKASRLAHAMGSPLTLLHLTHSSQVRnehielpaaersaraelAAKAGISELVATLSHPAEYQCLAVDDVVRDLAAWLASHPCDLLLVGSRHH-----WMEGSLARQLLYKLPVDIQICHE- ->tr|X1N7A9|X1N7A9_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_24280 PE=4 SV=1 --PVKKIVFATDLKElhNYKLYLNEVIRVAEIFDASIHFLHISNrekahPPESREVYKAIMEIIEWNKR-HVFRTCFGKDIISMVEEYIKKNEVELLAVVKHHHYFPETLFHKSFSNEVSLRSKVPVLVMREQ ->tr|A0A1W9QT36|A0A1W9QT36_9BACT Uncharacterized protein OS=Bacteroidetes bacterium 4484_249 GN=B6D61_10330 PE=4 SV=1 -QKLSNIIIALDQTDMSIGILHKAMDFCSLIDPKpaVTCLHIGHLPYYSELGEVAVEDYREFGNtdfkkisevffekqkesfenfieknlkgydnikPNIEFIGEKRvKPYHALKDYIDSGKADLLIMGTKSHSGFDNFLLGSFAEKMIMKT---------- ->tr|A0A1J5R473|A0A1J5R473_9ZZZZ Universal stress protein family protein OS=mine drainage metagenome GN=GALL_273590 PE=4 SV=1 -HSVKSIILPVG-SFIPEKKIQIAIAFAQKYNGLIHLVTMLDNSDEGhskmkvDIFYKTYKILQECGYTPQYKILSKYESHEILLRYAENANADLILLNPEKRSFLSTITVNAIVDFISPHSHLQVLMTKPN ->tr|I4C0D0|I4C0D0_DESTA Uncharacterized protein OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) GN=Desti_0279 PE=4 SV=1 ---MNGIGLCAIFSRQGDWAFDYALNLARHYKCKLNIFHFLESPYMLrrdvvfvdaektetapvtpeliaKKDKELRESFEDRlgDYVEVGFRLCEGNDEWELRKCFKKGDYEILVIGYNAKHAA---FGGTtTIEEFGAKFKGPLVLIGPD ->tr|I4CBA5|I4CBA5_DESTA Uncharacterized protein OS=Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1) GN=Desti_4209 PE=4 SV=1 ---MNGIGLCAVFSRQGDWAFDYALSLARHHKTKLNIFHFLESPYMLrrdvvfvdaekkettivnpdfiaKKDKEMREKYDDRlgDYVEVGFRLCEGNDELELRKCFKKGDYEILVIGYNEKGAS---FGGTtTIEEFCKKFKGPVILVGPE ->tr|E4NUY7|E4NUY7_HALBP Uncharacterized protein OS=Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 / PR3) GN=Hbor_34550 PE=4 SV --SLSSCLVPVARGPHLDTTLNIARVIGETHDAWIDFFHVVDNDESRSETDALFEYCTNHlgDFDEFDTWRYEGwSPAQAIVDQSS--YYDATVIAAPQKSRLREFVDGSTTEVVQSLCENTVVTVRSG ->tr|A0A1F3RTF0|A0A1F3RTF0_9PROT Uncharacterized protein OS=Bdellovibrionales bacterium GWA1_52_35 GN=A2X97_16640 PE=4 SV=1 -QPFDSIVVPMKGDPmRMDAALTYSLQIGGRARIPLDILHVSPKQLGPdssaigqlsdefyheyprrieEMIAEASPLSSVRERTIIRDFLQvRGDMTHEIFRSIKKHKSGLLVIEWDGKFARGR---SELIRAIILASHRPVLVVKP- ->tr|A0A1Q8B9W3|A0A1Q8B9W3_9BACT Uncharacterized protein OS=Acidobacteria bacterium 13_1_20CM_2_55_15 GN=AUG08_06900 PE=4 SV=1 ----ERILVGITPRSDARPILESGRRNADRFHGELFVAYVRQANLSpedEAALEENLAIARELDA-TIKVLDGQRDPARALIAFARDTGITQIFIGHSMRKGFWQRLRGNPVERLIDLAEgIDVRVFPQR ->tr|A0A1W9F1U1|A0A1W9F1U1_9GAMM Uncharacterized protein OS=Serratia nematodiphila DZ0503SBS1 GN=AK51_06495 PE=4 SV=1 ----DSILLCVGHNSGNEKLVRIAARLAARLGCHWHAVYVETPKLHrlpENqrrAILRALRLAQELAP-KPPPWPIR--PKSA-QCCATPANITSaksssaaaasnagscaaaspIASAGWARISI----W--------------------- ->tr|A0A1Y3GDF1|A0A1Y3GDF1_9EURY Nucleotide-binding protein UspA family OS=Methanonatronarchaeum thermophilum GN=AMET1_0138 PE=4 SV=1 -----KVVVPVRNPSTEFCLLKMAGAIIGGGVGELVVVNVVEVPPQIslsqsieaesrgldvqkkilDQAENLVGSLDRLGDVSLRTRAIVGrDVGSSVLRVLEEEDADHLVIGWDGEVSKKDYVLGSKIDPIVRGACCEVTVVKDG ->tr|A0A1Q6W979|A0A1Q6W979_9GAMM Uncharacterized protein OS=Gammaproteobacteria bacterium 13_2_20CM_66_19 GN=AUH10_13910 PE=3 SV=1 ---PQRVLIHWMSDASRSATLAVSASVLRHVAAEAVYVSIFPEERAGEQRHGLRELLDArseaqlaHGL-EMRTELRFGDVASELARRLAEAPAQMLIVGLSDLTGFAASF------RVLLETGqWPVLIVYRA ->tr|A0A1M5IRQ2|A0A1M5IRQ2_9FLAO Universal stress protein family protein OS=Spongiibacterium flavum GN=SAMN04488116_0889 PE=4 SV=1 ----KKISVIADISANLENVIANATELAKAIKGTVEVLYVKAPTDIvkgdnqlsamrtlhrdtrdtESKLRSAVEKFSSKTGSKVTYKIAYGNTKNTIKAYLEKEQPHTVVLGKPK-SKFPGIPASGIPSFIMTACDANVLVTGDD ->tr|D3F9J2|D3F9J2_CONWI Uncharacterized protein OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_0726 PE=4 SV=1 -PGPRRVLFPFLGRSLSKPALQAALRLARAEGATLVPVYLAEVPRHLpldcalpgqsavalALLDAIEQDARRCGV-PVDARIEKGrDSRHALREMMAHERYDRIVLAAETANGGDG-FSPDETAWLLANAPGEIVVLRPD ->tr|A0A0Q5UP24|A0A0Q5UP24_9FLAO Uncharacterized protein OS=Flavobacterium sp. Leaf359 GN=ASG38_04645 PE=4 SV=1 ---MKNLLIPSTLEKDTINAIKVAIQQSKGKSCTIYLALVSEIPDTYssaaflrniksdmsvsqkSILHSCRELVAASQNCSLKIHNQYGISAPVMKNLMEHLNIELTILTPSYKNTERR--IHNQFLQILANCKCPIL----- ->tr|A0A0N7K954|A0A0N7K954_FLAPS Uncharacterized protein OS=Flavobacterium psychrophilum GN=AMR72_12550 PE=4 SV=1 ---MKNILVPTTLQHDTLYSVKAAIKQSAGANCVITMVLLNEAPEAeSaayflrktkytnttaqsTVLENCRKAAYATDNCRLEIHNQYGLSAPLLKNLLEHLGTNLIIIPASYKKETGK--IHHHFLGLLANSRIPML----- ->tr|A0A1D9PAS8|A0A1D9PAS8_9FLAO Uncharacterized protein OS=Flavobacterium sp. PK15 GN=BIW12_09365 PE=4 SV=1 ---MKNVLIPSTLEPDTINAVKIAIQQSKGKKCTLFLVLVEEIPDSYssttflrsmksemtasqkKVLEYCRELITISQNCNLKIHYQYGISAPLMRNLIQHLEIELTILSPSYRKDERK--IHNQFVQILSNCKCPIL----- ->tr|M5TCJ1|M5TCJ1_9PLAN Uncharacterized protein OS=Rhodopirellula sp. SWK7 GN=RRSWK_06068 PE=4 SV=1 --RPARVMLVLDGSDQDPTSIASANHLRNVCNTETLVLDARETATDDSspdanaapptpssphpPSDLATQTAGQITG-ARAISRPSGESFEAILDSLKTHDVNLLIVPCPFGRSFGKVgadSVGTVVDVLLSRCSVPFLVIRHP ->tr|M2B4S6|M2B4S6_9PLAN Uncharacterized protein OS=Rhodopirellula europaea 6C GN=RE6C_02097 PE=4 SV=1 --RPSRVMLVLDGSPQDATSIETAKTLREEFNTETLVLDARDAAQPTDaATEDAIQAARQMSG-ARAIARGEGEAFEVILQALRTHDVNMVLVPCPFGRSFERVgtdSVGTVMDVLLSRCPVPILVTRRE ->tr|A0A1F3SGP4|A0A1F3SGP4_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA2_49_15 GN=A2X86_10535 PE=4 SV=1 --QFKKVSVLLDPTQNYDRQLGQVVKLIKRLKAKLHIICLVDVQFLglnleafpftpspleiqnktsqvllqkaELFLKELESGLKKDGI-EVEHTVHvtlNEENIYGLDKLLHEQAPNLVMISPRS-QFLGHFSLGSTTHYLMKHNNCNFYLLP-- ->tr|T0DM36|T0DM36_9PROT Uncharacterized protein OS=Bacteriovorax sp. BAL6_X GN=M902_2373 PE=4 SV=1 --NFKRITYLIPYESLDKDDLAKVANLARCNNAKVHMDCIVPLNFVsynlevfpegpypreiianemselhkgaEDELQKAVAILKEEGV-NANYTLKmilNADPGQRLEELVKEEKTDLVVIKPQH-YIFDHLSLGSITLDIMKNTDCNLYLLH-- ->tr|A0A1D6Q6L6|A0A1D6Q6L6_MAIZE U-box domain-containing protein 33 OS=Zea mays GN=ZEAMMB73_Zm00001d051397 PE=4 SV=1 ----DRVFVAVPEDAKnGKSTLLWALENPAKDCAGVVVAHVHCpaqmipmmgakvhhstvnpqrvneyrkkvRAEVEEKLDEYVLVCRRQKVSCQKVVIEMDDAVRGLEQLITLHGVAKLVMGAAADKHYSKkmkSLKSKTALRLTEVAApsCKIWFT--- ->tr|A0A1S3V5X5|A0A1S3V5X5_VIGRR U-box domain-containing protein 33 isoform X1 OS=Vigna radiata var. radiata GN=LOC106772098 PE=4 SV=1 ----DTVYVAVGNNAEkTQQLLHWTVNNFS--GKNVCLLHIHRphslnsfscatdknlsgyepkdlpiqafqdqgNQSVHELLDQYILDLVPAGVRACKLLIEMDDIEKGITEAIAQHSIRWLVVGAAADGYNMGklaKQDSEKAIFIREQALlsCNIWFI--- ->tr|A0A1F3SGP4|A0A1F3SGP4_9DELT Uncharacterized protein OS=Bdellovibrionales bacterium GWA2_49_15 GN=A2X86_10535 PE=4 SV=1 ---MKKFIVNTDLYESSDANVYTSYHLAKLLGLKPQLFFVDTISPMidktfhpesihtsyatdlvwqkkyeVTVLEKISQQLERLSLAkeDFDLEVFEGAISDGVKSLKRHEDIELLSVGASEHGEINRLFFNTFAEKIFFNLHKETLVVRKK ->tr|A0A1G1EVG9|A0A1G1EVG9_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWB2_47_37 GN=A2X55_03945 PE=4 SV=1 --GKKQLLFVTYHDENVEAGLSYAVDLAKTMNEDISILMLFRRKAMErledymtavafaeegefktareligedlkrrnesyeEKAGLLMKRCSDAGV-SVDVGASAADIVSAVRNLLRQNsKIDMVLLSPAVTEGGN--ISSKELNRLVKTSSRPVVTM--- ->tr|A0A1G1F872|A0A1G1F872_9BACT Uncharacterized protein OS=Nitrospirae bacterium GWC2_57_13 GN=A2X56_11390 PE=4 SV=1 --KKRKLLFVTYGEEGLEAGFSYAVELAKALYENIALLLLRKNGVKDsfenlmsavtfaeagehetamsmlktvsqnsleRKVSELVDQCGREGV-GVSVHTSDSDAVKGIKMFLKEHsGVDKVVLSPVVTEDGQ--VSSRDLNRLVRTASRPIVTM--- ->tr|A0A1F2TNI3|A0A1F2TNI3_9BACT Uncharacterized protein OS=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_66_21 GN=A3G21_12945 PE=4 SV=1 ---MREILLHGGSDEAFDRSAVFARRLAQSFGARLHVVYTVEDPLSAgwtaemgverlpeihqaieaearDRLARLIPMDEQERL-NVEIVVRTGAAGHELVRYTREASIDLAIVTAAPADDR----GVALARALLDHGRCAVLVLR-- ->tr|A0A0L8VCY8|A0A0L8VCY8_9BACT Triose-phosphate isomerase OS=Sunxiuqinia dokdonensis GN=NC99_11360 PE=4 SV=1 ---LNNYLYATAFHAEDLKAIKHLSETTAGADGKnLTIFHNMETLDFESKLKWIgFKTLVKDSVSGFHLKFEhanEKNVRDALKKYLTNESLDVIVILKEKKGFFEDLFSSSETHYVLTHFDKPVLIYHEE ->tr|A0A176WKN5|A0A176WKN5_MARPO Uncharacterized protein OS=Marchantia polymorpha subsp. ruderalis GN=AXG93_4773s1670 PE=4 SV=1 -QSPETIVVGVSLGQESQDLLAWACNTAAQSGDHIIALHVIDHSAIIakelqdgglekykssvafgltSLLDPLKELCTEKEL-TTQVRVVCGeTLDKVLVEEAAALGATLLVLSTSGR-RVAPWRIQGTASYCSRHAApgCSVVVVSNK ->tr|U5VIX3|U5VIX3_9PSED Universal stress protein, UspA family OS=Pseudomonas sp. VLB120 GN=PVLB_14405 PE=4 SV=1 -MKINHLLLIAPCDDRYSPAVEQSAELAMALDASVSLAALRAPSLGgqkpsvESYLKQRASHLASRGLRVSPDVTVLKPTANGVAAQVTRCGADLVVMDHAADEAAHQANLDL---QLLEKAPCPVLFAREQ ->tr|A0A1M6HEE7|A0A1M6HEE7_9BACT Uncharacterized hydrophobic domain-containing protein OS=Rubritalea squalenifaciens DSM 18772 GN=SAMN02745181_1452 PE=4 SV=1 ----GKVLLPCAGGPHSRRGLKIAADS---VGMDVTAFFVEPDVDDvsrAVGGVHLERYVKRAGVDPMSVERKvslNSDVYGAIRKEVETGEYGLMLIGASGASSIRRKLFGTVPDRLLRG----------- ->tr|B9WHV3|B9WHV3_CANDC Uncharacterized protein OS=Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841) GN=Cd36_5370 --MFRTILVYISGRIHTWVALDWILSKFIEDGDHIIIIASIDPCLLNtkdykdrsrrstsrtrmslspakigsqsslirgntlspqrsrtdesqpfqptsdiydpfirlkeksrpenivkianNLMDYIMKVINPKIITRITVELVEGDTKGVLQDMYRLYEPSLVCTGAKPNarvgAPLRSWQSSKLTDRLIKNFPLPVIAVPA- ->tr|A0A0A6KCP8|A0A0A6KCP8_CANAX Uncharacterized protein OS=Candida albicans P75010 GN=MGE_04316 PE=4 SV=1 --MFRTILVYVSGRIHTWVALDWILSKFIEDGDHVIIIASINPCLLSgsnkdrsrratsrtrmslspakigsqssvirgntlspqrsrtdepqstrqdsidpfirlkeksrpenivkiahNLMDYVMKVINPKIIARITVELVEGDTKEVLQDMYRLYEPNLVCTGAKPNarmgAPLRSWQSSKLTDRLIKNFPLPVIAVPA- ->tr|M3JYF5|M3JYF5_CANMX Uncharacterized protein (Fragment) OS=Candida maltosa (strain Xu316) GN=G210_1498 PE=4 SV=1 --MFRDIIVYISGRIHTWVALDWILSKFIENGDHVIIVAAVSPKLVDdkgrtgrsgtispqrgrtlsprrgastfspardedpvsrlldrsrpenicqigaNIMDYSLKIINPNIIAKITVEVVVGRTKDVLQDMYRLYEPNLVCTGSKPNmrlgAPLRSWQSSKITDRLVKNFPLPLIAVPA- ->tr|A0A183B1T5|A0A183B1T5_9TREM Uncharacterized protein OS=Echinostoma caproni PE=4 SV=1 ---PTTIIIPIDRNHPTLRTLELYYRTISSENYRIIFVHVIQPGNTNslfgirasmvssvtgnpvpikkKVLVEAKLLCREhvqhaqsHGLKAKSVIYVNSHVGPALIQAAARYRAD----------LF-------------------------- ->tr|R4M6T0|R4M6T0_MYCTX Sensor protein OS=Mycobacterium tuberculosis CAS/NITR204 GN=J113_07245 PE=4 SV=1 ----ERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGLAgvsapqLGRPR--LDKPRCDQ-PAlvLRRHAAGLRPRDERHAARRRHIAAIAMGTP------------------------------- ->tr|A0A1F9H889|A0A1F9H889_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RIFCSPLOWO2_02_FULL_40_36 GN=A3I69_09695 PE=4 SV=1 --KEKVVVLAVSKERKSQEAMHWAFHHAKETHKKVRAVYVVHQDESdgKKYLEDFEKQARTFQV-GYDSRLMMGDYLKACEDLSKEGESAVIVFLEKQKGFFKKLFEGSELDGLRMRFVCEMKVYR-- ->tr|A0A1V2M220|A0A1V2M220_9FIRM Uncharacterized protein OS=Epulopiscium sp. SCG-B11WGA-EpuloA1 GN=AN396_00600 PE=4 SV=1 ----KTILFSIS-NTIDMEALLYAQNEAIKEDAKLIVLYITSPLTFSscytypsvlysvanlniDNIEVAHEALSQKissilEDCPHQVICLIGPQIDSILNVAKEYNVEKIILPYES-SIIDKLSNKSMKLKLAKKCDIPIDIFGS- ->tr|E3H640|E3H640_ILYPC Uncharacterized protein OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_0009 PE=4 SV=1 --MLRKVVILFGNELNTENLLKTGKALKEKYNCEIKGLYVRDLRKHEiippsveglvvdpssryiveewekfesEQITILKDKFKSYFD-ENNLIVKDGVTPDTALEELK--GFDLLVLGKGER-------ISPDLKFILKNHYKPIIIVS-- ->tr|A0A0R1HUR8|A0A0R1HUR8_9LACO Uncharacterized protein OS=Lactobacillus kimchicus JCM 15530 GN=FC96_GL002467 PE=4 SV=1 ----KQIVVGVDGGHQAKGALDNAVKLSRAGQIPITLVQVVDPELTkhvanpqsylkhltETVEQELKALCEQLPADiKHSYQMTIGDPVNTLISYLKE-STNYLLVAQSNGGGYNIQKIGHVAKALMSNGHRNL------ ->tr|A0A1L8TP69|A0A1L8TP69_9ENTE Uncharacterized protein OS=Enterococcus hermanniensis GN=RV04_GL001236 PE=4 SV=1 --MSTKILVLVGSDGKPENAFRKAVELAEKEKSELHVLIYNTTLKENialeeseefsledgymgeltmpdiqlmedldeenqAEIKEFVSSINLSNPDNLIVSYVSYGLKKAVLNYANEKAIDLVILGQEE-TLYTRLTFDSLIKHVANKSASNLLIIK-- ->tr|A0A1E7H405|A0A1E7H405_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium S3730MH12 GN=BA862_01005 PE=4 SV=1 ------------DSAKSDTMVAELKKQALVCSADVTLLHVVEEESDShvrrygiavegeklmARLEETVQLFRRYGI-DPTIRLVRGEVVAVLAELCTELDAELLVLGSSR-KKEGILRSASVRRRLEKNCPCPLTV---- ->tr|A0A1G9NBS3|A0A1G9NBS3_9SPHI Nucleotide-binding universal stress protein, UspA family OS=Pedobacter steynii GN=SAMN05421820_102272 PE=4 SV=1 ---MKTILVLTDFSKNALIAAEEAALLAGRLNANLLLVYTDYGIPVStfypgifhgggdhswelhceremnkikNHLSRLFSLIDSNQCRpIISSRVSQGDLTGQVVNLLKDGNIALMAIGAATGIKTYPILSETEVYSMIETVGCRVLTFPEN ->tr|A8UV70|A8UV70_9AQUI Uncharacterized protein OS=Hydrogenivirga sp. 128-5-R1-1 GN=HG1285_16011 PE=4 SV=1 ---MRIVLILSDSSSECKKALETLDRYGEAFSADIGVFVILEDLYRlesasvslgvplppdtvksakertENKIKTLWRHIKKDEKAHIDIKAVAGELGEEVVKFVGEEKPDMILWGCQPTPVLCR---------VIDEINVPSLIIK-- ->tr|A0A1X7DKY1|A0A1X7DKY1_9PSED Universal stress protein family protein OS=Pseudomonas sp. URMO17WK12:I5 GN=SAMN02745903_01863 PE=4 SV=1 ----------LDDGDANAAVVEATRLITHARKAKMHLFCVYDQAALlrhsehyslaeipsyESLASAFKRFVAQLGIPDAYHQLIVGSCAHTLCAYANRCGYDTVVITSPHRAWQFA-----TLEYLLSSLKCSLLVVP-- ->tr|I3UFD2|I3UFD2_ADVKW Osmosensitive K+ channel histidine kinase kdpD OS=Advenella kashmirensis (strain DSM 17095 / LMG 22695 / WT001) GN=TKWG_19630 P ----EGILVVVDTALTpnaAQALIRHGSRLSGQMSCPMHVMFLREAANSRGPARSngdwqLLLQQAEQLQATTTEHYCNGDVMPDIVAYCRSQNLSRLLLDRSVLRRYWWRL--SPLVRVGQLGPdIDVIIYGG- ->tr|T4NTG6|T4NTG6_CLODI Universal stress family protein OS=Clostridioides difficile P28 GN=QSI_1894 PE=4 SV=1 ----EHILLCLSPSRSNALVIRTAARMASAFFAEFTALYVE-NVNEEPLCREDLEQLEQNRRlaqhfHANIVSVAGENIAQQISEYAKISGVSKIVIGRSSPRPHS--RARTLIDQLTLLAPdLEIYIIPD- ->tr|R4KCJ4|R4KCJ4_9FIRM Universal stress family protein OS=Desulfotomaculum gibsoniae DSM 7213 GN=Desgi_1404 PE=4 SV=1 ---MTRMLLAVNGAQYSTGAIKKAIWLSKLEDAQLDVLYVNPPCNQMypdipqlcfwmpdfeykmvtqrlrnkVLDGEIIPIFKEAGL-DPRVVVTSRDQDEKIKEMSTENHYDKIFIASPSR----------------------------- ->tr|A0A0F2PD24|A0A0F2PD24_9FIRM Uncharacterized protein OS=Peptococcaceae bacterium BRH_c8a GN=VR67_14490 PE=4 SV=1 ---MAKMLLVVNGADYSMEAVRKAVWLAKKDGAQVEVLYVNPTCVQLypnvpglcfwmpefeykirarqlmerVLNEDIKPILDEAQL-DIQMLTTEHDQDTEIKRLSEVNSYDKIFITGHSK----------------------------- ->tr|A0A1S2Y2I8|A0A1S2Y2I8_CICAR probable receptor-like serine/threonine-protein kinase At5g57670 OS=Cicer arietinum GN=LOC101490391 PE=4 SV=1 --GARTVVVAVKMESHthSIQLLTWSLVNVARPGDLLLALHVLRNdeivnRDGksslfslvkafDSVLSAYEGFCNLKQV-DLKLKICRGsSVRRILVREANEYCASHVIVGKPQGlSKIRP--SISIARYCAKKLSkdCCVLAVDNG ->tr|A0A1S3B0F0|A0A1S3B0F0_CUCME LRR receptor-like serine/threonine-protein kinase GSO1 isoform X1 OS=Cucumis melo GN=LOC103484690 PE=4 SV=1 --KGQPTFSGIIVDGGGARWLDGGDVQSAKWRHHLVAIHICEDldDG----LKFSESFP-VMKT-NEIRGSDSGeTFAKKLMKRLAKQRGMAVMLEFDPFGPLGN--LVSLAKCYFNQLPatSIVLAVHKG ->tr|A0A1Y1WLQ2|A0A1Y1WLQ2_9FUNG Uncharacterized protein OS=Linderina pennispora GN=DL89DRAFT_264304 PE=4 SV=1 -NRPYTIVVRIDDSREGYAAAEYACSLCLKLKVKYRLIFLYVVALYKrsnlnlinrqteqlnaeirenaedsmmkckQFLSRFESLLSFEWI-SIKDEGNVGPIAAKFIKKELQTVVDLVVVGRSADTALKTIVGGHVSDYFMKTLEVPLMVVKDE ->tr|A0A1R4IMD4|A0A1R4IMD4_9SPHI Uncharacterized protein OS=Sphingobacterium sp. JB170 GN=FM107_02595 PE=4 SV=1 ---MKAIIITTDFSESSLNAAKYAAAaeqitrstpvseirfWLERLTTKLLVLNVAGEGKRfdrdiTPKQYKMQDLLDGFYLE--NRYTENHNIADEIEDVAEDHHAGLIITIPKSYRFFEELFHRGVSKRLIRKLDIPSLLL--- ->tr|A0A0L8VCY8|A0A0L8VCY8_9BACT Triose-phosphate isomerase OS=Sunxiuqinia dokdonensis GN=NC99_11360 PE=4 SV=1 -------MLLLDTRKNMENLICSAFSLSNQLKRKLKIVYVLDIHWVGtgvtggelggptvpgisetymvveksirkdfeqaesEMRKTVAKYFEKYPQNvHYEIEVAEANRLDVVSKTVKR-EEDVLLLMSNYNTYSGLSTGTINYPNIIDKVPCPVLIIPDR ->tr|A0A0L0HL67|A0A0L0HL67_SPIPN Uncharacterized protein OS=Spizellomyces punctatus DAOM BR117 GN=SPPG_03425 PE=4 SV=1 ----RKLMVAVDAADQeGLRTLDWACKEMVQPGDTLVVVRVVKEQKGFkggyaaasemmksiesraheeadritCHALRALGQQSKKCI-DLYVKYRTGDPRSQIRELVGTEHPDVLIVGNNRKRVSNTFFHGGEQSFLPEGSNVPVV----- ->tr|A0A183C9W3|A0A183C9W3_GLOPA Uncharacterized protein OS=Globodera pallida PE=4 SV=1 ----RRVLVAIDGGGQSEYLVRVGRRIAERRDAPWTVVTVQRRREDDSTRREIDAAFALARRLGGEAELLHGpSIADALLDHAAHNSVSTLVLGRTRERPFARMLNRTLTQQLIQR----------- ->tr|K9YCQ0|K9YCQ0_HALP7 Uncharacterized protein OS=Halothece sp. (strain PCC 7418) GN=PCC7418_2568 PE=4 SV=1 ---MLKILLYVDVNQLdyNLNFLNRAIAYASALNGKFLLMTVLPDYDSYflspllpdqfkekadakvrEALEEFVARYLPEAL-MENIILRYGLVHTQILAVAEEEKVDLIFLNCDR-AEPVDYLLGTIEGRVNRRAPCDIVFFHR- ->tr|A0A1F9ELP3|A0A1F9ELP3_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_19FT_COMBO_46_12 GN=A2026_22455 PE=4 SV=1 -MTISKILIAVSATKDAPVLILDVFQIIEKNKASVKVLFISYLSDLFkkslgpntlhhwmkeekECIEKVISYFARMDI-PYHSKVIIVPPWEIIFYEMSEEGSDLIILQSELLERWkKDKANCALCSDVLSKSRCPILVIHST ->tr|F6DDM1|F6DDM1_THETG TrkA-C domain protein OS=Thermus thermophilus (strain SG0.5JP17-16) GN=Ththe16_0342 PE=4 SV=1 -HPYRSILVSAN-TEALSPLLASAMDLARIFGSEVYVLFVSRVEAFMppeekellENLKLLVERARKTSGLEVHLIRKEGNPVRETLKLLK-GKFNLLALGYTP-GRRTAFFRPYVPQLLAQASPVSTLLVPE- ->tr|A0A1V4Y793|A0A1V4Y793_9DELT Universal stress protein family protein OS=Syntrophus sp. PtaB.Bin075 GN=A4E74_01336 PE=4 SV=1 --------LIYNGCSEGDHSLDLAVSLSRQASWPLTILLPSEDPFRidslNRQLEDYFDQLTGEPLIDWDTVVLSGQQGEAAFRFLLDGSIELLVMSRPD--------LDSSMVMLLNKSPIPVIVTR-- ->tr|A0A0F2N781|A0A0F2N781_9FIRM Uncharacterized protein OS=Peptococcaceae bacterium BRH_c4a GN=VR68_15735 PE=4 SV=1 --MFKSILLVIGEDSGNSEIIPAAVNLAAVYGASLTAVFIAGHDYECmlgdewisdsgmlnrffsymesemnrrtvHVLDEVTEKCNNLGL-QVTVMQKTGNPGSAVISLYEEMGPFDLVVINKSLINRGDNRVKKGMDSVIRSLVCPMLIYPEQ ->tr|A0A1Q9N892|A0A1Q9N892_9ARCH Uncharacterized protein OS=Candidatus Odinarchaeota archaeon LCB_4 GN=OdinLCB4_15270 PE=4 SV=1 -----KVLLPVSVKVNRELLLRSFEILKGLKNLDLIVFHVLELPMTAsldisehnqkvqelnQQLEPTIKWIEEQSFKIKSKIVVARHVSEAIVEEANSGNYDLVVLLKREPpKGVRRLFYRSHTDYVTGKLNCAALIL--- ->tr|T0Y1I1|T0Y1I1_9ZZZZ Universal stress protein UspE (Fragment) OS=mine drainage metagenome GN=B1A_22114 PE=4 SV=1 -----RIAAAVDVSEEeteglAASIVRIARRLALATGGELDLIYAEHLSAEhaesRTHAGRLRNLARQADLDEHHAYILAGPPERELAAFAAGRDYDVLALGALTHRKVAVQLVGNLTATLVEALDSDFLLIKPD ->tr|A0A1F8PCV4|A0A1F8PCV4_9CHLR Uncharacterized protein OS=Chloroflexi bacterium RBG_16_48_8 GN=A2Z14_01725 PE=4 SV=1 --PIEKILLILRCENRDHIAVDWVVKMGLPSKAVVTMSVPLPPIPRmyqglsgmsvqipkmlkgnsalEKHLQSLTARLASHGI-EVKLNILEGDTKRIIQQEVMEGEYDLVSVAAKPESWLKRTLLSSVVNPVLEYARIPIFIAKP- ->tr|T0MWF5|T0MWF5_9EURY Uncharacterized protein OS=Thermoplasmatales archaeon I-plasma GN=AMDU3_IPLC00002G0307 PE=4 SV=1 ---MKDVMVAIDSPEYLERALREVVYLFPEAE-RFDLVYLMPVNYShfwvpdqqkresskRKIEEKIREVFSSNRSIaaKFRIEIIENDPDRELMELSRRENVDAIVIERWSHWKGGHSITKRVAIKTISNSGIPVTILN-- ->tr|A0A0S8B7V2|A0A0S8B7V2_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12960 PE=4 SV=1 --AFGRDLVKGTGGRVRALG----IIRGRA---------------SDeakskayesvr----TNVARLEDATG--IEIEIVEVvSAQEDLYQAFG--QYDLMILGASEEGFLRPTTFTGFPADTVAGAEHAGMVIKK- ->tr|F4KNS9|F4KNS9_PORAD Sodium/hydrogen exchanger OS=Porphyromonas asaccharolytica (strain ATCC 25260 / DSM 20707 / BCRC 10618 / JCM 6326 / LMG 13178 / -----QVLISFGRAETGVTLLEFFHRLCGGTspQVACTLMHVTTDTDIstidadhyyASSFAAPMEMAKQLDLSVERKYEIAESVPEAVLSHANHIQSNLLLLGASV-NLSQDKKDRDlvaysdkltrrwkvvtgrrrqakkeqsshsfeeIIATFAHEAPCSV------ ->tr|A0A0U2XUN4|A0A0U2XUN4_9FLAO Transporter OS=Myroides odoratimimus GN=AS202_13570 PE=4 SV=1 -----QVSLFFEDKTSLAPLMRLASSFVGKNnaDTGITAMHLVDSIEVnaftsteyeNEIFEAVQEEATALDQEVQTYYKVSNDIESDVVNVVNEQISDLLLIEVGY-SIYRGSLLGNilgfttriinpdvllnkvtgkekffenswfnaRTQQILNRSKVPV------ ->tr|K1HXH2|K1HXH2_MYROD Uncharacterized protein OS=Myroides odoratus CIP 103059 GN=HMPREF9716_01196 PE=4 SV=1 -----QVFLFFENKLSLAPLMKLANAFTGKSsvDTRITAMHMIDSQELnsfntqdyeEEIFEAVQEQATEMDQEVQTYYKVSNDIESDVVGMVHQETCDLLLIEMGY-SIYRGSVLGNilgfttriinpdvllnkvtgreklfenswfnaRTQQIMNRTKVPL------ ->tr|R5GGA1|R5GGA1_9PORP Sodium/hydrogen antiporter OS=Porphyromonas sp. CAG:1061 GN=BN460_00182 PE=4 SV=1 -----HILFSFARSKMGLTMLHIVESLFAKPeeSVELVGLHLTVGSDTsksdaelyrSQNFAPIQSHADASGYGVEEYYEVTDDPLHSIAKATRVKGADLLLVGAGL-ELSANPEDKAmrerhlkfgrsfskifsqtinffnlhnlfedHTEDFVRIPHCAI------ ->tr|A0A0G0U8M5|A0A0G0U8M5_9BACT Uncharacterized protein OS=Candidatus Uhrbacteria bacterium GW2011_GWF2_40_263 GN=UT94_C0056G0006 PE=4 SV=1 -RGEGPLMIPFGVGPTALQVLSSCLPLIKIFGQPVLFYHTTWEKKGmsssqprdhmcraaYDVLAQLCAKAHAEGIAYGEYIEKVSFVESGIVRAALEQGVSLLIMGRAKDVG-----RGSYVDQVLERSPIPVLVM--- ->tr|M7N716|M7N716_9BACT Uncharacterized protein OS=Cesiribacter andamanensis AMV16 GN=ADICEAN_00437 PE=4 SV=1 -MRCKKILIGFGSTIYSELEVDFTIRYLAQPKMLLVGAVLNDLQGLPqhepcedskckgsaqacvqkkvgkdrqRLHAYLHERCEALCC-RAVVHQDGGTTLDALMHETR--YADLLVISQETYLASTtSGGQLVPVSRVLENCDCPVLVVPPH ->tr|A0A0D3LJZ7|A0A0D3LJZ7_9BACT Uncharacterized protein OS=Flammeovirgaceae bacterium 311 GN=D770_20760 PE=4 SV=1 -MRCKKIIIGFGSSEFSELEIDFTLRYLAQPKMLVVGTVITDLLVPNghtacseggctgegqscvhkntqrdrtRLYHYLQEQCKDLGA-KSVIHQESGSTLEVLMHQTR--YADLLVLSQETYLASVAGPLPLPVSKMLETCSCPVFVLPAK ->tr|E3H640|E3H640_ILYPC Uncharacterized protein OS=Ilyobacter polytropus (strain DSM 2926 / CuHBu1) GN=Ilyop_0009 PE=4 SV=1 --KFDKVMIANDKSFKINKSFFRFMSIFEDIkEFDSYSVGLEDEE-----DNSFSEYLQGSDK-VIRTKECQGDELEVLIEEAK--EHNLLIMGNLTHSYLVEKITGHIGVKLIESLKIPIFIA--- ->tr|A0A0X8JUM2|A0A0X8JUM2_9FUSO GntR family transcriptional regulator OS=Leptotrichia sp. oral taxon 847 GN=AXF11_05505 PE=4 SV=1 --ELENILLLDDGAYNANKTLFTFLYMFGEQKINVLRVNSD--I-----EKEEDGLVQRFGK-NYNLIYKKGETFKTLLQETK--NYDFILMGDLRYTIMVEKITGKLGIRLLENVKKPIFIV--- ->tr|A0A1C6FQB5|A0A1C6FQB5_9FIRM Uncharacterized protein OS=uncultured Ruminococcus sp. GN=SAMEA3545392_02234 PE=4 SV=1 -KATESILVCVNHPDFSKELIAYGKRLSLEMNLPLQVVNIQPSANGYcargHEIELFYQQCKEAGAE--LTILFDDDFAGATAKFARKTGAKQVVTQLFSsesGG---------------------------- ->tr|A0A1M5KI47|A0A1M5KI47_9BACT Universal stress protein family protein OS=Aliifodinibius roseus GN=SAMN05443144_13219 PE=4 SV=1 -----TVLVPIHKAELFKTLLPSAIEAAKKYNGKVLLLNVIKKPYLAspqkaeekrpkrtSFLSEGMSMLHQAECKREIQIEISPDISRTIKRIAQMRAVHLIVMGSNGN---QRAIFKNEIPYNLQQLACSIMVARGT ->tr|X1PQS7|X1PQS7_9ZZZZ Uncharacterized protein (Fragment) OS=marine sediment metagenome GN=S06H3_45391 PE=4 SV=1 -SDISTVLYATDYQETDPFHINRLIELLHPFSEVIRCVHVTTGSKAENkplNLEKLKNFFDSHSPAiQISFHEWKGeNVRKGLLEFAGVYEVDLMTMLLQKRNFLENLTHFSKSRNVVHDSKIPIIIMHEH ->tr|Q3A854|Q3A854_PELCD TrkA domain protein OS=Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1) GN=Pcar_0177 PE=4 SV=1 --PYQRMALPCMAEGQLQASMQTALEIAAPLHFNLEALVCKPSEYIasndelsgCERICKTIDRLRHIYRTEIHETLVEGNPIAVFSEALQEHKLLVANIGEWRQPRlWPDWLDPDVPWHVVDRANISTLLLPAD ->tr|A0A0B5FLX5|A0A0B5FLX5_9DELT Uncharacterized protein OS=Geoalkalibacter subterraneus GN=GSUB_02365 PE=4 SV=1 --PWEKVAVPCTDPENVQHVLETALEMSSAIKYEIEALLVRPSDYIatdeeqdaFTVMKKTVSDLSYIYKATIHATELSGNPIRSFCDHAKDYSLVVSDLTAWSDRGfIRSLFNPDVAWNIVRKTPVSVMVVPPP ->tr|Q1YZ12|Q1YZ12_9GAMM Uncharacterized protein OS=Photobacterium profundum 3TCK GN=P3TCK_07801 PE=4 SV=1 --KNKTIIVAADiHNDSSFKLISEACDMADQWDADLHLAYSIDMPAAFtdptvyaywpqlqgalkelpysEFEHDKSFIIDTFPFEANHIHIMTGDVALRVAELAKSIDASLIVTGKSHHKF---HITHNHAKQILQAVDTDILFLK-- ->tr|D3FFI9|D3FFI9_CONWI Uncharacterized protein OS=Conexibacter woesei (strain DSM 14684 / JCM 11494 / NBRC 100937 / ID131577) GN=Cwoe_5377 PE=4 SV=1 -PEPARILLVANRTAATDGLRDAVRARAARGPVRFHLVVPAHPHGLhkvvdpqegdhgeaQQRLEQALPQLSaAAGA-PVTGHVGDAEPLMAIEDALNQAHYDEIVISTLP-RRISRWLHLDLVSKAR-GSGLPVTHV--- ->tr|A0A239DA77|A0A239DA77_9ACTN Uncharacterized protein OS=Geodermatophilus pulveris GN=SAMN06893096_10362 PE=4 SV=1 -TDERRVLVLANQTLCGDRLVEVVTERVAAGPHAFHVVVPATPVREqegppgtgdddvltapvrayalaQQRLDRAVEQIRAAGA-SASGEVGDADPLVAAELALEHFPADEVLVLTLP-QRFSRWLRGGLPSRVGRASGLPVQHV--- ->tr|A0A085FS36|A0A085FS36_9BURK Universal stress family protein OS=Massilia sp. LC238 GN=FG94_01145 PE=4 SV=1 ---YRRALVLVDPAVSITETLAHLGGVA--PGAEIVLLAALERKGENrlrasgagedrieaSVQQQREDALQGMGAPDGVVRIVEHGYAPTVLQYAErRLQPDLLVLPNERTARLRRLFLRSLVGEALARSDCDILALPAG ->tr|A0A109CWN2|A0A109CWN2_9BACT Uncharacterized protein OS=Nitrospirae bacterium HCH-1 GN=ASN18_0146 PE=4 SV=1 --SKGKVTVIVYPGFTYKESITYGSDAAKMLDSVLNIKAVVPEFGISertalsmyefgvhgkiqaqaereaeAFFDSVKGFCKTSAI-EAVFDKGIGAIDDVIEEIKAEaHGINTiIVVPMPTNNMTHIAYNDEndyriEKTNNNPLKSCNVVLV--- ->tr|A0A1R1YKG7|A0A1R1YKG7_9FUNG Uncharacterized protein OS=Smittium culicis GN=AYI69_g3165 PE=4 SV=1 -------------------AAWTALNICHKDNDHIFLTCCIKEDKIfdpavvseiinnifsdeevkidkksivEAHFEKIKDMLVAKGI-SASVDIHVGNDSTATD-IIHAHRANLVVAQPAEMSALGKTFSLDWAETLSRSSICPITIVRGN ->tr|A0A1G2D0X6|A0A1G2D0X6_9BACT Uncharacterized protein OS=Candidatus Lloydbacteria bacterium RIFCSPHIGHO2_02_FULL_50_13 GN=A3D65_05230 PE=4 SV=1 ------ILVPLGDGDSSIVAAARGIALAQTLGTEVIFWHTTWKNVHEksadprkhvyptaeAILSEAEQMGRAANVTREACRVEcAETVVESIIRVALRSGTSLVVMPRGKRKK-----YGAYADRVRaRNCPVPLLILARE ->tr|A0A1V6CQY0|A0A1V6CQY0_9BACT PTS system mannose-specific EIIBCA component OS=Planctomycetes bacterium ADurb.Bin126 GN=manP_2 PE=4 SV=1 -RMVRRVLVPAGGGAHALEGIRIADVLAKAWSLDRQVLRIIHPGPEfwerradlkrrcRHIRNATLLYLDVAEVEMPVKVRLGGDVADEIICHSR--LGDLIVIGGSSQWLMENHASASIPSRVASGVSGPVLMV--- ->tr|B8CYW6|B8CYW6_HALOH Uncharacterized protein OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) GN=Hore_17360 PE=4 SV=1 ---VTKIMLILFSMAQMSKSIDYSLKLASENEASLDVKFIIEEKIPRtlsslvmytgflgekmgediektlleeyynrarKVLTEIKKRAKESDI-DYDTEIVKNGSLTYCYQEIKNNNIDYLIINYTRDRFISEQVLDYYLEDFLSDLEIPYELFYDG ->tr|A0A1W9P5Y0|A0A1W9P5Y0_9BACT Uncharacterized protein OS=Candidatus Cloacimonas sp. 4484_209 GN=B5M53_06570 PE=4 SV=1 ---MKKLMLVLSNISFSASSVNYAIERAEKEEFELVAVFVLDEEIPEsvssllmyigflgpkptddlkatllseykkraaSELEHVEKLAGEKNI-PMKKVLRKGKFVDEVLKVQEEEKADLVVTSKSRSPMLSQILSSYNLDELKNRLNEKLVVIEE- ->tr|A0A151CE28|A0A151CE28_9PROT Uncharacterized protein OS=Sulfurovum riftiae GN=AS592_03335 PE=4 SV=1 -EKIEKVLVVIQETDKIESLLRQAIRLCEGHAAVMEILYIHQSPLFElpdyfkrsetegldseRVEKEIETTLERLGNTsSYAIFIKESETVDQVLALDKGEGQTCIISFYHEE----------ITPVLARKVSSPLLVMKSE ->tr|A0A1W1CKN1|A0A1W1CKN1_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MNB_SV-14-730 PE=4 SV=1 -HIFKRMVVVANDIENIDTLLEKAVACSKQHQTTLEVLFVHEEPLFKlpdyflsdekiskskidknKIKKSIQEKLTALNYNkTVSILVLVDDTLDQVLEYGKENKDILFITAYHKE----------LNRKLLQKSPYSFWIVKNK ->tr|A0A0S8B7V2|A0A0S8B7V2_9CHLR Uncharacterized protein OS=Anaerolineae bacterium SG8_19 GN=AMJ56_12960 PE=4 SV=1 -----LVYVPDVERARPLITAG--ALLARSRKVPMLVLQVIETAGAsipvgkqpdtqhAlSLQDQLLENNRLDDIHIIPLVRLAPTVRQGIMATIWDEQVATALVSWPADEDEGKGLSIEEVMRLVRRAPCEVVVLRDK ->tr|A0A1F2R8G3|A0A1F2R8G3_9BACT Uncharacterized protein OS=Acidobacteria bacterium RBG_16_68_9 GN=A3J75_00495 PE=4 SV=1 ------MLLLTPPNRDPQAAAREAIAMAKSRGGELVIAVVLDPEVIErlstrldevglmgervsdtvrntlareyrsradTLAAHIVEEAQREGV-LSEVVIEEGDPSAICSRLVRKHQITLAILVAERRSWLTRLLSGSAAR---------------- ->tr|B1L589|B1L589_KORCO Nucleotide-binding protein, UspA family OS=Korarchaeum cryptofilum (strain OPF8) GN=Kcr_0872 PE=4 SV=1 --NPRRILFPVVEDFSPDKLRALISGTIGISNAEITLLHVVRVPmtapldeetfsgelaEWEGKLRRLAEQLEGGGLRARVRVVLSRSILTGIEECLQGHDMLLLVRGTFG-GTFRKVIARISIEKLSEKYRTPIIVISRN ->tr|A0A1U8J2A8|A0A1U8J2A8_GOSHI U-box domain-containing protein 35-like OS=Gossypium hirsutum GN=LOC107902882 PE=4 SV=1 -KRNESVAVAIDKDKGRQHALKWAVAHLISRGQSITLLHVKTKPSSIptpsgshvkmsdvndevakaykqqlesqakEVFLPFRCFCSRKDIKCNEVILEDTDISKALIDYVSSFPVETLVLGAPSRSGFvRRFRTAEVTTNVSKGAPdyCTIYVIGKG ->tr|A0A101IMX2|A0A101IMX2_9CHLR ABC transporter related OS=Anaerolinaceae bacterium 46_22 GN=XE06_0165 PE=3 SV=1 -PRLGKALICLESGEPGKDNVAFAGRLLRHLGADATLMTVITNEAQddsqqrriERFLTAGKNSLARFGV-DANIQIRTGPLISAIQEEMKTEAYDLLVLGAPLPNAYGKVDLHGTIGTILNSVEnCSFLIIRS- ->tr|A0A1L9C4Z8|A0A1L9C4Z8_9EURY Uncharacterized protein OS=Methanohalophilus portucalensis FDF-1 GN=MPF_0351 PE=4 SV=1 ---INTVLVAFSATSIHRNLAKAALDMAEEKDARLIILNVRDKNMAEkvarvtkdqgfmgrgvveklaadikrdrdeliaQRLGMVEEEAGKRGI-EFETVKVKGDFVKQVIETAGMYGADVVMVASSSV----------VN-DIEKKIDAEVYSF--- ->tr|I0I708|I0I708_CALAS Uncharacterized protein OS=Caldilinea aerophila (strain DSM 14535 / JCM 11387 / NBRC 104270 / STL-6-O1) GN=CLDAP_30060 PE=4 SV=1 -PRLKHILVVLRGHGADMQALSWAAAIARAESTGVALLVLNEMGGCDlhalldpettigRHLAAVTRLATAKGI-EPSLRIRQGAPLRQIVDEAATQRYDMVVLCAESQGEFAATVLRELA----------------- ->tr|A0A0C2VNM3|A0A0C2VNM3_9PROT Uncharacterized protein OS=Sulfurovum sp. FS06-10 GN=KU29_08070 PE=4 SV=1 -EHYENIVLPIDLKEHSRTCIEATQHIF--PNSKLSLVYDYRYILDvlalredylnvvplttgvdmefneelkAQQKETFDAYVTEFNA-TGYFMEGEGLLDEDLIAYIQKEGFDLTVLYHNDEELF---FSPTLILDLLEELSTDFLMWS-- ->tr|A0A1W1BTJ7|A0A1W1BTJ7_9ZZZZ Uncharacterized protein OS=hydrothermal vent metagenome GN=MNB_SV-3-841 PE=4 SV=1 -KNYQKMALIVDVGTPSLSCIERAKSCF--PKIDIELFYDYRYIVDpsmeadlqniqiieEAQREGFKKLKEESGL-DGKFFIDGDFLGKQISDYLQEKNFDIIYACSHEDGFF---VSDNLSNTILKDLSYDMLIVN-- ->tr|A0A1J5DZ02|A0A1J5DZ02_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium CG2_30_66_27 GN=AUK27_02155 PE=4 SV=1 -RPVRTIVAGCGGGSRSERVVGAMARLSLWKSSPRGILLAVDDDPEggRERIATPRRILADAGYPVWEEKILPGPRAETVLSFCESVDADVVVLGGWGEHRWDDLLGLSVTGRMLADGQRHLFLY--- ->tr|A0A1Q6DRV2|A0A1Q6DRV2_9EURY Nucleotide-binding protein UspA family OS=Candidatus Methanohalarchaeum thermophilum GN=BTN85_1755 PE=4 SV=1 --KIGKVAAFIKKEKDSntLETLKRANQFQTESqESKLNIIHINGKNNSkNKTRERLKEKIEEANISREDYKLRiynRENIVESIINESK--NFDTVCLGSTQLSRFKKPTFGSIPKKIALNSNENVVIIK-- ->tr|A0A087GUI4|A0A087GUI4_ARAAL Uncharacterized protein OS=Arabis alpina GN=AALP_AA5G026200 PE=3 SV=1 ---MKNVMVIIDESNSSYDLLIWVLANLKDTieSSKFFIFAKQPQNSFTptsvlsssvgsaqmfypfssnaelmglaqaknmkialGILDKAKKICLNHGI-KAETLTDVGDPKTIIRKTIQEQKIDLLVMSDQQTRTLKK---------CLNNTNCSLLVARNG ->tr|A0A1V5NJ37|A0A1V5NJ37_9BACT Universal stress protein family protein OS=Bacteroidetes bacterium ADurb.Bin397 GN=BWY67_02110 PE=4 SV=1 -KPATKLVYTTDLKDDNIKAVNDLIPFASSMNSELIFLFVDDkihtdSEKISEDMSSKIRQLVQYPK-TSGYICTDPNVMNGISLFIEKQHVDMIAMLTHPRKFPQMLWDKSLTKKFSYHPNVPLLVLHAN ->tr|C5LZK0|C5LZK0_PERM5 Putative uncharacterized protein OS=Perkinsus marinus (strain ATCC 50983 / TXsc) GN=Pmar_PMAR003859 PE=4 SV=1 --------------------------------------SIDESNDYERRFKNIASEYPQLET-TFDVAEATKDIRDTLMEYCSETEPDLVAIGSGGSTHYLK--LASLVEYVVRESPCDVLILREN ->tr|A0A0Q0YYL6|A0A0Q0YYL6_LEULA Uncharacterized protein OS=Leuconostoc lactis GN=AN225_03740 PE=4 SV=1 --QMRHFLVAISKSLSSDNAIRWAYRQASAFDAPWTVVHVQQSGKSlAPAVQRHMSLAKKLGAK--TVILQGDHVVATLIAYIRETQVANLIIGKHVTRAWYQFGRSDIEDQILAAVPaLDIQIIPN- ->tr|A0A1F9BKY4|A0A1F9BKY4_9DELT Uncharacterized protein OS=Deltaproteobacteria bacterium RBG_13_60_28 GN=A2Z73_01380 PE=4 SV=1 --MAKKVLVAVNLKIPTPWAVFYGVHLAARLKAPLVLMAVFPGGvkkksktslaleaelpeEQRLWLEQVVEQCQQEEI-RLEIFLSSGPFFEEVAQFLASHrGIQFLVVGVPRDSPVTEREGSDAALKRIHHVfPGEILLVREQ ->tr|A0A1B7LG75|A0A1B7LG75_9FIRM Uncharacterized protein OS=Desulfotomaculum sp. LMa1 GN=A6M21_07440 PE=4 SV=1 -----NALLFTDLSQPSLSCAAYTAIMAKnNPEMKLTIITGSNENCAkknssdhwsgydvkfpqeQKILDRVKQVLENKGYNYEEWQADNCaRLAKKLVNYARDNNISTIIMPNHCKEDLKSMPVGHLASSVICLSEIPVVLVR-- ->tr|A0A1G9CAC8|A0A1G9CAC8_9GAMM Universal stress protein family protein OS=Dyella jiangningensis GN=SAMN04487785_10826 PE=4 SV=1 -RQLGHILAVYDGSPETILAVEHALLLARRIRASVFILGLYPPLDRAadapairaamvDELIAYIHAGRRLGL-DVDAQCPDEVSHGSVERFIADLHIDQIVVPKVGEH--SRPWTAALVRDLLQSCTVPLVIC--- ->tr|A0A1B7XBT7|A0A1B7XBT7_9DELT Uncharacterized protein OS=Halodesulfovibrio spirochaetisodalis GN=SP90_10635 PE=4 SV=1 -HGRRNVLLCVDGSRSSRNITEHVAKMLAGNPLHtITVLHVAPGKKYTtaspsvaflnkqfrnqrkaqcfisktshRVVAEAVELLVANGVREEAIETRlahSNDPASVIMETSDQGNFAVVAMGRSGTgnSFMRHMLMGSSVAHVWKKLNNACL----- ->tr|A0A1E2ZJJ4|A0A1E2ZJJ4_9GAMM Uncharacterized protein OS=Candidatus Thiodiazotropha endolucinida GN=CODIS_02010 PE=4 SV=1 -SKPLRVGAILDTGMASQKLLETITELGKSPDIGLTLFLTPDEETPQKAALQSYLSQQDPHQ-LINVVYINDLEPAALANQLKRSACDLLMISEQSP-----LLQGPTIKQILERLPYPTVVVR-- ->tr|F9UGX3|F9UGX3_9GAMM Uncharacterized protein OS=Thiocapsa marina 5811 GN=ThimaDRAFT_4176 PE=4 SV=1 -NGGPLVGVLYSGSEGATRALAIALELVVRHAANLVVILQPEISADT-ATLRGRvLEqLATLHE-QTRLVSLEGADAAGLSATVGKLGIDLLILDETNP-----LLARASLWNSLESLGCPVVIGR-- ->tr|A0A0F2J325|A0A0F2J325_9BACT UspA domain protein OS=Candidatus Magnetoovum chiemensis GN=MCHI_000422 PE=4 SV=1 -----KILCAVNGSERSFNALRSACRIAVKNSLSLNAFYVNSSCMYcpeltrwsyierriekeqdalsAEIYRKNRDIGKEFNI-NIDCLTSSGEVDAEINAFLNENGiYKMLVIGHNNKS----IFSENIVKNIIVNCNIPVLTTSSD ->tr|B9LVS4|B9LVS4_HALLT Uncharacterized protein OS=Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34) GN=Hlac_3261 PE=4 SV=1 -NALGRVLIASRHTKNAEAKVNTLLNIVDRDELlSVDLIHVADPDDPegeaegESVLKSMSSILTDQGIPsiRINQEVRKGsDVSFELRQAAR--NYDLFVMGATE-QDVGDEVFGPVGDYIVHEQDVAVLTLR-- ->tr|A0A1G2H7M4|A0A1G2H7M4_9BACT Uncharacterized protein OS=Candidatus Spechtbacteria bacterium RIFCSPHIGHO2_01_FULL_43_30 GN=A2827_00030 PE=4 SV=1 -RNPVRVLVPFrvkSHNQNNRLLAETVTAFSKFFDGKPTFLVIDDD-KKGSARQKIEKDLRDIGIPedlaGDIRIIHAGVVADRILEMSK--DFDVVIMGSSRGGSFSEITLGQTAELVLERCETTTIVVRHH ->tr|A0A075AII1|A0A075AII1_9TREM Uncharacterized protein OS=Opisthorchis viverrini GN=T265_02177 PE=4 SV=1 ----RKVCIPVNPKQDLRQIFHWYDEHIRHANDSLLFVSIVKPQFAIpvlagtaieisradvkrakEICREAMQLAKKHGLRANSYVYIGMNQKKTLTQFLREFKPDLVLVEKQVKNIILRKLTGdSQVKAVMASQNCVLVALPP- ->tr|K1YD23|K1YD23_9ZZZZ Uncharacterized protein (Fragment) OS=groundwater metagenome GN=ACD_75C01983G0001 PE=4 SV=1 --MKKHFLVTISNDTDNLYGVRFACSFFDiLSEHTLTLLHICRLDSSDmqktltemwknpdddlrdkipigarRAIEKSKELLSQSKISidqviTKTVAERYGKVRDILNEGAE--GlYDAIILGRRAAYSLQWVFEKPageIAHAMIRNSCCasPLWICPE- ->tr|V4IY43|V4IY43_9DELT Uncharacterized protein OS=uncultured Desulfofustis sp. PB-SRB1 GN=N839_15480 PE=4 SV=1 --MKKKFLVTVSNDFDQLTAIEFLCSFFLpQSRHQLTLYHICRLDSNDmnkallqmwdepdarvakrlsfgarKSLDRATDMLGSSQMSvddiiTKTVAERFGKVKDILSEGAG--GlYDAIILGKRASYALQWFFERPadeIAQAIVNDPSFstPLWICPE- ->tr|A0A0F2NFB5|A0A0F2NFB5_9DELT Uncharacterized protein OS=Desulfobulbaceae bacterium BRH_c16a GN=VR65_11495 PE=4 SV=1 --MKKHFLVTISNDAEILYGIRFICSFFEdISNHQVTLLHICRRDAADmagtlsqmwngpsdgiqgrltvqakKSIDKAKEIFSRHRMSieqvmTKTCAERYGKVKDILTEGAK--GYDAVVLGRRASYSLQWMFERPadeTALAIIRDNCCttPLWICPE- ->tr|A0A0K9PK62|A0A0K9PK62_ZOSMR Protein kinase family protein, putative, expressed OS=Zostera marina GN=ZOSMA_235G00060 PE=4 SV=1 ----KKIFVGLSLNTDGRELLSWTIAKLAGAGDHVVAVHVCRKSDVqnrsvelDEYIRGFDALCRSKEVTLMGRIAEGTSKKKQLLKEANFFNATVVVVGVEKRLSSFWMPTALVAKYYKKKLKstMDFFAVHDG ->tr|M0LS16|M0LS16_9EURY Universal stress protein UspA OS=Halobiforma lacisalsi AJ5 GN=C445_05903 PE=4 SV=1 ---MQVYLVGTDSVHATAAVCDYLERRGAGDGKEIEVIAVAASGDEDgdrvgdrvgdrvgdrvgdgeepgerdAREALNVARVRLPFVDTLRTEYRDTALAPALAEVAAEHEVDEVIVGRTTSsseteaNGDGSTGAGSVVDGVLEGTSRPVVVVP-- ->tr|U7JFC7|U7JFC7_9ACTN Uncharacterized protein OS=Propionibacterium sp. KPL1844 GN=HMPREF1275_01426 PE=4 SV=1 -PMSDHPLVVAVFPGIPVRIIEAALEHARAHRCELVMAYVDESRVPVadgegsvplipdeertpcherevDLRTALEQVMSAHPDITWQFRYLAGLTDRELAHLAHTVNAGAFMVGTRAPGFRwqaKEWFDGSVAIQLSRRQRRPIIIVP-- ->tr|A0A1Y2CCD7|A0A1Y2CCD7_9FUNG Uncharacterized protein OS=Rhizoclosmatium globosum GN=BCR33DRAFT_717010 PE=4 SV=1 ---PQTVLVALDPTSPNEHTLRWVLsNLVKTERDVIVIITVIATEADREQTENAWNTLVSglslntmtKPV-PVILTAPTSSIGPRICAAVTDMNPSVLALGSSRNQLSSE---PSITNYCLANADCKVVVVRND ->tr|A0A0C2MW94|A0A0C2MW94_THEKT Uncharacterized protein OS=Thelohanellus kitauei GN=RF11_03286 PE=4 SV=1 ------IVVGLDTSDYAEQVIEYVVKYIYRPGHHIIALAHFLGTKHIgshyiwnhveidcrtfcpkgkkkledslAKLENIEKMLNENKV-RYIRYFESGskKKEDYLWDIAREIGAQCIVVGISHLSMLKD-LRSHRGYDLSAKSGIPVFIVK-- ->tr|G4SVR7|G4SVR7_META2 Uncharacterized protein OS=Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z) GN=MEALZ_2446 PE=4 ----------YDGMEGSERAFKLAIDIAESQKSGLNIIlQRQSDNRIAEMEQQVKALLAGSNL-ASHFFIQSSRSYDSIMQYVLERGCSIVVLRADRTDPEAS---QSAASLFADRLGCPVLLV--- ->tr|A0A1Y1HQR0|A0A1Y1HQR0_KLEFL Uncharacterized protein OS=Klebsormidium flaccidum GN=KFL_000670320 PE=4 SV=1 -----RVLIAVNDSPESRAALEWATENLIREGDQVLLYHLVKTPKLIpvttgmvpylkvapemqrahnavavhnatSLLRSCQRFCISKKVFAKVEVGRCDQREAELLRKVEQNGITHLVMGTSQPAKFslRPRKKPGLTARICQAASCHVILVDE- diff --git a/esm/examples/some_proteins.fasta b/esm/examples/some_proteins.fasta deleted file mode 100644 index 6b85419..0000000 --- a/esm/examples/some_proteins.fasta +++ /dev/null @@ -1,30 +0,0 @@ ->UniRef50_A0A1E3NP16 -AVIYYRFRSQKPDHIATIKFDGTGLTVFELKRDIILANNLLHSTDVDIVLYSTEDIQDTKSWGYQNGGSSSAGERELDDDNEVVPRSTTVLVRRTMTPKKNKGNVQRYVAGKPRLQVSGTNSVNKSISLGNNVGGTMNFGDAATNGDEDDMIKKMFSVQDEQWSQQQDVMATATRVDNFRTNVNEPVPEYYICYKCGEKGKHHIKNCPKNNDPNWEGVRVRKTTGIPKSHLKAIENPEDTIRDSNSSGNTTYMVNDEGKYVVAVADTKAWEKYQKTKKGESGGYLNGDVDVDDGELKDPETGKLWKSPVRIPCCNKIFSRKIIEDKLIDSDFTCPSCGKEQIYLDTLVADEELQAKVDEYVKNLSENKNNDGNSPKRRQVNPAGATANTSQLPQIPMMPMPPINMQMPPMNIGMPPFMPFMPMPGMNP ->UniRef50_UPI000836A30F -MTLRTLLALSILALAAAATVQARPGAPPCSPLGLKYQPGACEKWKREHPDVNPDGVVQTVTIVNNSSSVLGGYVTFWHANNEHTDVDLPGVKPGETWTANGSWTVGQAPYYLLYSSFQDSYGDPVTFYAVPISKYPALAKKLPPEPDNCQSNHFRMVFGDGPQYVYEQHSGAVVTGGQTDKNTLCQILGCPTGGSTAGGLNTQNRTTSRSAPQPVYFRSCDP ->UniRef50_A0A2G8L8Y3 -MAQKRYEENLSPYAELFRSKLIEDFHLLESFDEHGKSDAPKYYSKDFEDPARQDKMMLENPHGLVKFQVYSRKEPGEHFMLVLILSNSIALGLQAEVSESDDPKFAGLKLALDIFDYCSLFLFMVEIILKWIDNFWSFWSDNWNIFDFAVTVGSFVPEIINFFAGDIGGSMVRVIVRNLRVFRILRSLKMVSRFRQVRLIALAIGKAFSAITFIMLLLFTFLYIFAITGIIFFDTYTRSERQDLKYKDSFRSLPRAMITLFQLFTLDQWYKLLNDMWKVMDSMIPLGYIILWICIGSFIFRNVFVGIMVNNFQSIRNDLFEEVKEQEAARQIIQDTEKFNEELSRQEKKLNANRRGTLYQSPTVQPPKPNQPQPSQLAGLDNSETDEQSVSQEDESNTDGQTSLSGTDSYDLLGESSDSLFRRSSDGMIDKDKLSTNWEKTVHDNLTLLTSTPSETLWPRDTLFRYFQLMESLMENLQERQDLQDLAYHSLLQIFDSFDTSA ->UniRef50_A0A1D5ZRM3 -MPCVAHECHPRLPAANHCRSLSCLGTPAAGWSSGDDDREEDELDTKQVILNEMRNREMRKRSSRCSVDSPTLSGAFAWSFTPLHPRSSIEKVSCTEEEKEAASDSDNESEAFFSVKSFFTRSTSRAATVASSTDMDPPATWEGLRGCEGWPFGLCP ->UniRef50_UPI0003108055 -MPADAREYLESKHATRRFDRPAEVAGVVAFLLSDDTSFVIGAGYLVDGGYTALRAARGRLGPRRQAAPAVKLLPNTDSPR ->UniRef50_A0A223SCH7 -MGPPRWWKGITGLAAVVHRADPEDKADLYAKMGLYLEYHPETRIVEARIKPRLHDVCESKVSEGGLEPPCP ->UniRef50_A0A090SUK6 -MKTPEDRVFRATDEYSDFVMACRYKGNEREFVIASHDKLNEAQVETLTSYLSGEWFKKTYITGIMNDSDGVLSQHEEYGDEVFCQPLDELRVDRYIMMV ->UniRef50_V4AGU2 -MHLGSIYLMVVLLIYFAYTDDRKERENVDVINPEENLVQDDEQYVGDSTENIEKSGSEEEEEDKEAIEEEEDEEEELNYRYIPEPAQDIVDNGKKYIQVHCSFKQDESLIRHPSNCSRYFVCSYGVVEEMPVCDDGEVFSIQVSECVKKGSENDDCDKLPFDSPPEITRGTQPSLIWHPRHKSPRSQFRQPTTLQMKVPHIELESFTCSATGKVLSHHSENCAWYYNCSAHPDAVMQTFYSGFIMECPYPQLFSTETKQCEDFEDVKCGDRYEPKSPCDYRANHCHETSHCIPCWVRYASCLELPDGLNPWSELEWKPFFVECYKERTVFQGVCDKSAVFSPLTRACETPYSIPRQHGGWRPVCDGRRDGIYADEYGRCDIYYVCKGYIFTGFFRCEKGEMFNPVISICQKPEAVPYPCGDLEMPNICESSLNGYHLDMFGRCTHYFECKDQQLEGISMCPSGIFNPELQICESSRDQPKPCGNLTNLCTHKNDGFHSDENDCTKVFQCERGLTMTSYDCSGSVRTECDVCNTPTECNDKPNGLYPNLKEGVGYYYDCVRSQIQNHYKCDKEKGGPIFNPVKQRCFYPEDLCKEVFSLKIAW ->UniRef50_R5PKX9 -MQGGEQDVFEHRQVREKVIALKNHADAAAQGAAEFERLSFEQDVAALDGFETDQAAQKRGFAAARRPENHRDFFVVKREVDAVENHSVAELLYETARFQNNVIGHFYAFHFFSRALAASDTGQHARK ->UniRef50_UPI0003674933 -MKKKEDILNLEHTLLPWMGRTMKVLDYFIGDFLNLKGIELTKVQWILLKKLNEQNGQPQQNLAFLTNRDKASLARLITTMEKKKLVERIPSKIDGRINHIFITKHGCEILQKSAPVIEKVVGCIQEGISPEEIETVIKVMQKVNNNINRASN ->UniRef50_E9K9Y4 -MADNVLMAYHIVHDPDERAKHVLNTKKLYKWRITEKTKGTPVVGNVALVQTQFAKRTPVMIYATKEVANDLSDLQPVKVFTNNRDQETVNQTFDDLMR ->UniRef50_A0A2C9LWN7 -MGKITGLLFFLFTSVRVTPSMKNTVNDIYRVRKDVLTKYRNTEEYDLGQRKGPLKQMDTRETRTPYGHFNSDTAFISPKNILKATRPLAFHLGNLKNQTSPCSTWNLTVDCSYKSLDHIESSWFPSNTTVLLLNNNKLVTLHNETFAQLTNLTRLDLSSNDIRRIDAGAFQGLHNLQELNLHMHCCNFTDHYSLESVFAPLRNLRILNAMHNSDVGVLTYSYTFLTRLPLLQSLSIDFDLDTLYCGPEFNDLKNLTFLQFSGQVMYIDDRSFQNVAQLKNLSMDHLSNINNISHNAFKPLSNLKVLTMYHVLLYVQEILSLLEPFQGRNMTEITLDTTTRTLTQVNPTRNGILTNHDTKYLMNICLESFTLIDNRIFYIKPDAVQNIYTWKKCLMHLYIASNPIQGNNFALIRLFTLDNLKSFTFINMFRACHEFQPFPQSSPPATRNVASSSISSQNNHYQKDTTSNQQQMIRHSPFSPYLDMIDENPYQLNIPNYIFISPSLQYMNFQRLVMSQSFEYHFILVGAQNVTSLDISDSGFYRFNGLMEGVSAIKTLIISGNDVSVLSVSFFDTFVSLENFAISSCKLDRDFISLNSRRIFQNHTRLQELDISSNSLNYLSQNTFSYNNRLMWLNMSGNQFKDIPFDLTNTPELQFLDIRFNSLTTIDETTAQQMDHLVTKSGKLEILLEGNVLSCSCSDLSFMRWMRMTLVTFDQNGNFTCMNTDGERKYTLDYSNLDSLWRECWGSFFLYFALIMLCLYCIGVFAVFITMRNKNFIVSFFLQLFGGFKLHSRRDYPVGVYIGYSDKDYQFPCKELRSFIESSLKLKTFLIDRDLIASVDKASGIIEALNASWRILLVCSKSFLKEDDWSMFTMRSAIYTQTPANPARVVVLVHKDCLPLLPPALLSSVNDENICAVSEWAMNYEMMQMLTTRLH ->UniRef50_Q9REE6 -MSLRGRELLTSEERLELVRIPEDISEQELGRNFTLSNFDLELIKNRRRDYNRLGFAVQLCVLRFPGWSLNDAEPIPKKVLQHLARQLHVDPDCFSLYSSREA ->UniRef50_A0A226D4M8 -MQKVINFPIWRRYYFSECGNCNDFRPDGVKKVHPPQEKSRTMDDEILAAPEVTIPFEPSDPSEVVVNLISSEEEDDDDVIQIVEEKSVDKAERQRRRQKKKDLWAARKLQRNKGQNVPLQTAWQRGPRPQETSSFPTPPQQSGGAQQKPLSPILISTAGSPNTSGAPTPANVSQQPTPTPSFVHTTASTSTHPEISLNINSDLALLIRLGPDGRPILTRVENVEQNNTSTSTPTTTRKLPPAPPPPKISFDTQTGESLLNGELITRPIIDITTDSPPSITHAATVSPQTSRTSGPPTLSPISPPPRTTQSNPAHPPPRYEPRKSRHPPRDPLASSSSSSSSSPSPPPTSRARHTSSANIPPPLEPLFLNTTQLIHLIKTCRKCEKSFPTRCDGVIHQKKEHNRKHCPVCFLTLSRHGNTYKDHLNMYHALEGDKEMVVCPFCAVEHSFDGLYNHIGRSHLIPVESKGESEHEVIFSVAPSPQSNGHQTRSVTQGNTPPKNDTNSPPNLEKRRPGPASKTRKTTNDPVPSTSRTGLICHKYVPDVETPPSKAGRNFESRAGRNFESRNVYPPATNRLNPPRNKSPPRNKNLPRNKSPPRNKSLPRNKTPPPSSSRSSSSRSVSNNLRRKNPTPPPPTQPPPKKVAKPDEAGINEKIQAAIKAVNARVHIERSVHHPNNRSDREIPSTSRTVTSRHKVPTSKTSGNTSVRKDPSPPPPLQTPPKTTNLELSKVQKARIVEDVRSIVRDVRITRVLDDGEVPSTSRAVEEEKKKEEKKNETRARLPRSSRVGERSSGYFQMAEGIDFSPENPTPRSKDLKAIHISKLNLIYQQLKCYPDTSVIANVAKECGVEIPVVAKWFTKKHMEYCQKTQQRKRKRKPPELR ->UniRef50_UPI000B82D8F0 -MGGLHLIELRNVNIEFDKKLIEDGTIKIYDGKITAIIGESGSGKTSLLYLLGLISSNHRYLYSFDDVTLDLSNDFEMSRIRKQKIGYIFQDNNLVENLTIFENIRLSATIAGINITDKEIKSYLEFVELGYIDSNHYPRKLSGGERQRVAIACALAKQPELILADEPTSALDTVNSEIIMGIFKKIAHKDKKKIVIATHNDRIYNEADVIYEIKNNKIQLVKGESSNESSKKEPEDYDNNVKLTPRFYFDYAIKTSRKGRFAKNLMIVLSAIAIAFSSVMYNFGDTFVKEQEKLMDAISDKEIFVVNMTAPLNTILDIDENLSIQDKDAELLRNISYVDTIYPYFEFRSIGYPLINETEASEGYIVVSKGQKEEKYTFAESKDNPYDKYVIIPYYPEQNLERRLKEKLSDESSDKVYISSQLAQLLGIENLKESVSLRVLTYVPIAQHETQMTVRPEGIVYEIDIDLSKVVELDLKIEGILDESVRNRYSNSGNNAIYVPYHKMQMILTQTQNSATIDTNLEYIEWRPSAFVVFAKSYNDVGLVIERVSSINPNFRAVSEYQDIESMNAIVKNTREIGLVIVIVILIIIFLLMSIIHMNHILDRKYEISLLKANGLTKIELTKLVSVESLRHVFLVSLISSVISLVVTKVMNLLFEEIA diff --git a/esm/examples/sup_variant_prediction.ipynb b/esm/examples/sup_variant_prediction.ipynb deleted file mode 100644 index 24cd324..0000000 --- a/esm/examples/sup_variant_prediction.ipynb +++ /dev/null @@ -1,487 +0,0 @@ -{ - "cells": [ - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "[![Open In Colab](https://colab.research.google.com/assets/colab-badge.svg)](https://colab.research.google.com/github/facebookresearch/esm/blob/master/examples/variant_prediction.ipynb)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "# Variant prediction with ESM\n", - "\n", - "This tutorial demonstrates how to train a simple variant predictor, i.e. we predict the biological activity of mutations of a protein, using fixed embeddings from ESM. You can adopt a similar protocol to train a model for any downstream task, even with limited data.\n", - "\n", - "We will use a simple classifier in sklearn (or \"head\" on top of the transformer features) to predict the mutation effect from precomputed ESM embeddings. The embeddings for your dataset can be dumped once using a GPU. Then, the rest of your analysis can be done on CPU. \n", - "\n", - "### Background\n", - "\n", - "In this particular example, we will train a model to predict the activity of ß-lactamase variants.\n", - "\n", - "We provide the training in `examples/P62593.fasta`, a FASTA file where each entry contains:\n", - "- the mutated ß-lactamase sequence, where a single residue is mutated (swapped with another amino acid)\n", - "- the target value in the last field of the header, describing the scaled effect of the mutation\n", - "\n", - "The [data originally comes](https://github.com/FowlerLab/Envision2017/blob/master/data/dmsTraining_2017-02-20.csv) from a deep mutational scan and was released with the Envision paper (Gray, et al. 2018)\n", - "\n", - "### Goals\n", - "- Obtain an embedding (fixed-dimensional vector representation) for each mutated sequence.\n", - "- Train a regression model in sklearn that can predict the \"effect\" score given the embedding.\n", - "\n", - "\n", - "### Prerequisites\n", - "- You will need the following modules : tqdm, matplotlib, numpy, pandas, seaborn, scipy, scikit-learn\n", - "- You have obtained sequence embeddings for ß-lactamase as described in the README, either by:\n", - " - running `python extract.py esm1_t34_670M_UR50S examples/P62593.fasta examples/P62593_reprs/ --repr_layers 34 --include mean` OR \n", - " - for your convenience we precomputed the embeddings and you can download them from [here](https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz) - see below to download this right here from in this notebook\n" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### Table of Contents\n", - "1. [Prelims](#prelims)\n", - "1. [Loading Embeddings](#load_embeddings)\n", - "1. [Visualizing Embeddings](#viz_embeddings)\n", - "1. [Initializing / Running Grid Search](#grid_search)\n", - "1. [Browse Grid Search Results](#browse)\n", - "1. [Evaluating Results](#eval)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "\n", - "## Prelims" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "If you are using colab, then uncomment and run the cell below.\n", - "It will pip install the `esm` code, fetch the fasta file and the pre-computed embeddings." - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "# !pip install git+https://github.com/facebookresearch/esm.git\n", - "# !curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz\n", - "# !tar -xzf P62593_reprs.tar.gz\n", - "# !curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593.fasta\n", - "# !pwd\n", - "# !ls" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "As an alternative to pip installing, you can just put the repo on your python path:" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "# import sys\n", - "# PATH_TO_REPO = \"../\"\n", - "# sys.path.append(PATH_TO_REPO)" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "import random\n", - "from collections import Counter\n", - "from tqdm import tqdm\n", - "\n", - "import torch\n", - "import matplotlib.pyplot as plt\n", - "import numpy as np\n", - "import pandas as pd\n", - "import seaborn as sns\n", - "\n", - "import esm" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "import scipy\n", - "from sklearn.model_selection import GridSearchCV, train_test_split\n", - "from sklearn.decomposition import PCA\n", - "from sklearn.neighbors import KNeighborsClassifier, KNeighborsRegressor\n", - "from sklearn.svm import SVC, SVR\n", - "from sklearn.ensemble import RandomForestClassifier, RandomForestRegressor\n", - "from sklearn.naive_bayes import GaussianNB\n", - "from sklearn.linear_model import LogisticRegression, SGDRegressor" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "## Add the path to your embeddings here:\n" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "FASTA_PATH = \"./P62593.fasta\" # Path to P62593.fasta\n", - "EMB_PATH = \"./P62593_reprs/\" # Path to directory of embeddings for P62593.fasta\n", - "EMB_LAYER = 34" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "\n", - "## Load embeddings (Xs) and target effects (ys)\n", - "Our FASTA file is formatted as such:\n", - "```\n", - ">{index}|{mutation_id}|{effect}\n", - "{seq}\n", - "```\n", - "We will be extracting the effect from each entry.\n", - "\n", - "Our embeddings are stored with the file name from fasta header: `{index}|{mutation_id}|{effect}.pt`" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "ys = []\n", - "Xs = []\n", - "for header, _seq in esm.data.read_fasta(FASTA_PATH):\n", - " scaled_effect = header.split('|')[-1]\n", - " ys.append(float(scaled_effect))\n", - " fn = f'{EMB_PATH}/{header[1:]}.pt'\n", - " embs = torch.load(fn)\n", - " Xs.append(embs['mean_representations'][EMB_LAYER])\n", - "Xs = torch.stack(Xs, dim=0).numpy()\n", - "print(len(ys))\n", - "print(Xs.shape)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### Train / Test Split\n", - "\n", - "Here we choose to follow the Envision paper, using 80% of the data for training, but we actually found that pre-trained ESM embeddings require fewer downstream training examples to reach the same level of performance." - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "train_size = 0.8\n", - "Xs_train, Xs_test, ys_train, ys_test = train_test_split(Xs, ys, train_size=train_size, random_state=42)" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "Xs_train.shape, Xs_test.shape, len(ys_train), len(ys_test)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### PCA\n", - "\n", - "Principal Component Analysis is a popular technique for dimensionality reduction. Given `n_features` (1280 in our case), PCA computes a new set of `X` that \"best explain the data.\" We've found that this enables downstream models to be trained faster with minimal loss in performance. \n", - "\n", - "Here, we set `X` to 60, but feel free to change it!\n" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "pca = PCA(60)\n", - "Xs_train_pca = pca.fit_transform(Xs_train)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "\n", - "## Visualize Embeddings\n", - "\n", - "Here, we plot the first two principal components on the x- and y- axes. Each point is then colored by its scaled effect (what we want to predict).\n", - "\n", - "Visually, we can see a separation based on color/effect, suggesting that our representations are useful for this task, without any task-specific training!" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "fig_dims = (7, 6)\n", - "fig, ax = plt.subplots(figsize=fig_dims)\n", - "sc = ax.scatter(Xs_train_pca[:,0], Xs_train_pca[:,1], c=ys_train, marker='.')\n", - "ax.set_xlabel('PCA first principal component')\n", - "ax.set_ylabel('PCA second principal component')\n", - "plt.colorbar(sc, label='Variant Effect')" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "\n", - "\n", - "## Initialize / Run GridSearch\n", - "\n", - "We will run grid search for three different regression models:\n", - "1. [K-nearest-neighbors](https://scikit-learn.org/stable/modules/generated/sklearn.neighbors.KNeighborsRegressor.html)\n", - "2. [SVM](https://scikit-learn.org/stable/modules/generated/sklearn.svm.SVR.html?highlight=svr#sklearn.svm.SVR)\n", - "3. [Random Forest Regressor](https://scikit-learn.org/stable/modules/generated/sklearn.ensemble.RandomForestRegressor.html?highlight=randomforestregressor#sklearn.ensemble.RandomForestRegressor)\n", - "\n", - "Here, we will be using the PCA-projected features because we observe it does just as well as `Xs` while allowing for faster training. You can easily swap it out for `Xs`." - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### Initialize grids for different regression techniques" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "knn_grid = {\n", - " 'n_neighbors': [5, 10],\n", - " 'weights': ['uniform', 'distance'],\n", - " 'algorithm': ['ball_tree', 'kd_tree', 'brute'],\n", - " 'leaf_size' : [15, 30],\n", - " 'p' : [1, 2],\n", - "}\n", - "\n", - "svm_grid = {\n", - " 'C' : [0.1, 1.0, 10.0],\n", - " 'kernel' :['linear', 'poly', 'rbf', 'sigmoid'],\n", - " 'degree' : [3],\n", - " 'gamma': ['scale'],\n", - "}\n", - "\n", - "rfr_grid = {\n", - " 'n_estimators' : [20],\n", - " 'criterion' : ['mse', 'mae'],\n", - " 'max_features': ['sqrt', 'log2'],\n", - " 'min_samples_split' : [5, 10],\n", - " 'min_samples_leaf': [1, 4]\n", - "}" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "cls_list = [KNeighborsRegressor, SVR, RandomForestRegressor]\n", - "param_grid_list = [knn_grid, svm_grid, rfr_grid]" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### Run Grid Search \n", - "\n", - "(will take a few minutes on a single core)" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "result_list = []\n", - "grid_list = []\n", - "for cls_name, param_grid in zip(cls_list, param_grid_list):\n", - " print(cls_name)\n", - " grid = GridSearchCV(\n", - " estimator = cls_name(), \n", - " param_grid = param_grid,\n", - " scoring = 'r2',\n", - " verbose = 1,\n", - " n_jobs = -1 # use all available cores\n", - " )\n", - " grid.fit(Xs_train_pca, ys_train)\n", - " result_list.append(pd.DataFrame.from_dict(grid.cv_results_))\n", - " grid_list.append(grid)" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "\n", - "## Browse the Sweep Results\n", - "\n", - "The following tables show the top 5 parameter settings, based on `mean_test_score`. Given our setup, this should really be thought of as `validation_score`." - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### K Nearest Neighbors" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "result_list[0].sort_values('rank_test_score')[:5]" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### SVM" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "result_list[1].sort_values('rank_test_score')" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "### Random Forest" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "result_list[2].sort_values('rank_test_score')[:5]" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "\n", - "## Evaluation\n", - "\n", - "Now that we have run grid search, each `grid` object contains a `best_estimator_`.\n", - "\n", - "We can use this to evaluate the correlation between our predictions and the true effect scores on the held-out validation set." - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [ - "Xs_test_pca = pca.transform(Xs_test)\n", - "for grid in grid_list:\n", - " print(grid.best_estimator_)\n", - " print()\n", - " preds = grid.predict(Xs_test_pca)\n", - " print(f'{scipy.stats.spearmanr(ys_test, preds)}')\n", - " print('\\n', '-' * 80, '\\n')\n" - ] - }, - { - "cell_type": "markdown", - "metadata": {}, - "source": [ - "The SVM performs the best on the `test` set, with a spearman rho of 0.80! \n", - "\n", - "This is in line with our grid-search results, where it also had the best `validation` performance.\n", - "\n", - "In conclusion, our downstream model was able to use fixed pre-trained ESM embedding representations and obtain a decent result.\n", - "\n", - "(For reference, we report correlation of 0.89 in Table 7 of [the paper](https://www.biorxiv.org/content/10.1101/622803v3), but this was achieved by fine-tuning the model)" - ] - }, - { - "cell_type": "code", - "execution_count": null, - "metadata": {}, - "outputs": [], - "source": [] - } - ], - "metadata": { - "kernelspec": { - "display_name": "Python 3", - "language": "python", - "name": "python3" - }, - "language_info": { - "codemirror_mode": { - "name": "ipython", - "version": 3 - }, - "file_extension": ".py", - "mimetype": "text/x-python", - "name": "python", - "nbconvert_exporter": "python", - "pygments_lexer": "ipython3", - "version": "3.8.5" - } - }, - "nbformat": 4, - "nbformat_minor": 4 -} diff --git a/esm/extract.py b/esm/extract.py deleted file mode 100644 index a8a3903..0000000 --- a/esm/extract.py +++ /dev/null @@ -1,146 +0,0 @@ -#!/usr/bin/env python3 -u -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import argparse -import pathlib - -import torch - -from esm import Alphabet, FastaBatchedDataset, ProteinBertModel, pretrained - - -def create_parser(): - parser = argparse.ArgumentParser( - description="Extract per-token representations and model outputs for sequences in a FASTA file" # noqa - ) - - parser.add_argument( - "model_location", - type=str, - help="PyTorch model file OR name of pretrained model to download (see README for models)", - ) - parser.add_argument( - "fasta_file", - type=pathlib.Path, - help="FASTA file on which to extract representations", - ) - parser.add_argument( - "output_dir", - type=pathlib.Path, - help="output directory for extracted representations", - ) - - parser.add_argument( - "--toks_per_batch", type=int, default=4096, help="maximum batch size" - ) - parser.add_argument( - "--repr_layers", - type=int, - default=[-1], - nargs="+", - help="layers indices from which to extract representations (0 to num_layers, inclusive)", - ) - parser.add_argument( - "--include", - type=str, - nargs="+", - choices=["mean", "per_tok", "bos", "contacts"], - help="specify which representations to return", - required=True, - ) - parser.add_argument( - "--truncate", - action="store_true", - help="Truncate sequences longer than 1024 to match the training setup", - ) - - parser.add_argument( - "--nogpu", action="store_true", help="Do not use GPU even if available" - ) - return parser - - -def main(args): - model, alphabet = pretrained.load_model_and_alphabet(args.model_location) - model.eval() - if torch.cuda.is_available() and not args.nogpu: - model = model.cuda() - print("Transferred model to GPU") - - dataset = FastaBatchedDataset.from_file(args.fasta_file) - batches = dataset.get_batch_indices(args.toks_per_batch, extra_toks_per_seq=1) - data_loader = torch.utils.data.DataLoader( - dataset, collate_fn=alphabet.get_batch_converter(), batch_sampler=batches - ) - print(f"Read {args.fasta_file} with {len(dataset)} sequences") - - args.output_dir.mkdir(parents=True, exist_ok=True) - return_contacts = "contacts" in args.include - - assert all( - -(model.num_layers + 1) <= i <= model.num_layers for i in args.repr_layers - ) - repr_layers = [ - (i + model.num_layers + 1) % (model.num_layers + 1) for i in args.repr_layers - ] - - with torch.no_grad(): - for batch_idx, (labels, strs, toks) in enumerate(data_loader): - print( - f"Processing {batch_idx + 1} of {len(batches)} batches ({toks.size(0)} sequences)" - ) - if torch.cuda.is_available() and not args.nogpu: - toks = toks.to(device="cuda", non_blocking=True) - - # The model is trained on truncated sequences and passing longer ones in at - # infernce will cause an error. See https://github.com/facebookresearch/esm/issues/21 - if args.truncate: - toks = toks[:, :1022] - - out = model(toks, repr_layers=repr_layers, return_contacts=return_contacts) - - logits = out["logits"].to(device="cpu") - representations = { - layer: t.to(device="cpu") for layer, t in out["representations"].items() - } - if return_contacts: - contacts = out["contacts"].to(device="cpu") - - for i, label in enumerate(labels): - args.output_file = args.output_dir / f"{label}.pt" - args.output_file.parent.mkdir(parents=True, exist_ok=True) - result = {"label": label} - # Call clone on tensors to ensure tensors are not views into a larger representation - # See https://github.com/pytorch/pytorch/issues/1995 - if "per_tok" in args.include: - result["representations"] = { - layer: t[i, 1 : len(strs[i]) + 1].clone() - for layer, t in representations.items() - } - if "mean" in args.include: - result["mean_representations"] = { - layer: t[i, 1 : len(strs[i]) + 1].mean(0).clone() - for layer, t in representations.items() - } - if "bos" in args.include: - result["bos_representations"] = { - layer: t[i, 0].clone() for layer, t in representations.items() - } - if return_contacts: - result["contacts"] = contacts[ - i, : len(strs[i]), : len(strs[i]) - ].clone() - - torch.save( - result, - args.output_file, - ) - - -if __name__ == "__main__": - parser = create_parser() - args = parser.parse_args() - main(args) diff --git a/esm/hubconf.py b/esm/hubconf.py deleted file mode 100644 index 95368e9..0000000 --- a/esm/hubconf.py +++ /dev/null @@ -1,14 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -dependencies = ["torch"] - -from esm.pretrained import (esm1_t6_43M_UR50S, esm1_t12_85M_UR50S, - esm1_t34_670M_UR50D, esm1_t34_670M_UR50S, - esm1_t34_670M_UR100, esm1b_t33_650M_UR50S, - esm1v_t33_650M_UR90S, esm1v_t33_650M_UR90S_1, - esm1v_t33_650M_UR90S_2, esm1v_t33_650M_UR90S_3, - esm1v_t33_650M_UR90S_4, esm1v_t33_650M_UR90S_5, - esm_msa1_t12_100M_UR50S, esm_msa1b_t12_100M_UR50S) diff --git a/esm/pyproject.toml b/esm/pyproject.toml deleted file mode 100644 index 95693a4..0000000 --- a/esm/pyproject.toml +++ /dev/null @@ -1,12 +0,0 @@ -[tool.black] -line-length = 99 -exclude = ''' -/( - \.git - | __pycache__ - | build - | dist - | experimental - | third_party -)/ -''' diff --git a/esm/setup.py b/esm/setup.py deleted file mode 100644 index c1723b4..0000000 --- a/esm/setup.py +++ /dev/null @@ -1,27 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -from setuptools import setup - -with open("esm/version.py") as infile: - exec(infile.read()) - -with open("README.md") as f: - readme = f.read() - - -setup( - name="fair-esm", - version=version, - description="Evolutionary Scale Modeling (esm): Pretrained language models for proteins. From Facebook AI Research.", - long_description=readme, - long_description_content_type="text/markdown", - author="Facebook AI Research", - url="https://github.com/facebookresearch/esm", - license="MIT", - packages=["esm"], - data_files=[("source_docs/esm", ["LICENSE", "README.md", "CODE_OF_CONDUCT.rst"])], - zip_safe=True, -) diff --git a/esm/tests/test_alphabet.py b/esm/tests/test_alphabet.py deleted file mode 100644 index a3545ec..0000000 --- a/esm/tests/test_alphabet.py +++ /dev/null @@ -1,60 +0,0 @@ -def _test_esm1b(alphabet): - import torch - - batch_converter = alphabet.get_batch_converter() - - data = [ - ("protein1", "MKTVRQG"), - ("protein2 with mask", "KALTAISQP"), - ("protein3", "K A I S Q"), - ] - _, _, batch_tokens = batch_converter(data) - expected_tokens = torch.tensor( - [ - [0, 20, 15, 11, 7, 10, 16, 6, 2, 1, 1, 1], - [0, 15, 5, 4, 11, 5, 32, 12, 8, 16, 14, 2], - [0, 15, 5, 32, 12, 8, 16, 2, 1, 1, 1, 1], - ] - ) - assert torch.allclose(batch_tokens, expected_tokens) - - -def test_esm1b_alphabet(): - import esm - - _, alphabet = esm.pretrained.esm1b_t33_650M_UR50S() - _test_esm1b(alphabet) - - -def test_esm1v_alphabet(): - import esm - - _, alphabet = esm.pretrained.esm1v_t33_650M_UR90S_1() - _test_esm1b(alphabet) - - -def test_esm1_msa1b_alphabet(): - import torch - - import esm - - # Load ESM-1b model - _, alphabet = esm.pretrained.esm_msa1b_t12_100M_UR50S() - batch_converter = alphabet.get_batch_converter() - - data = [ - ("protein1", "MKTVRQG"), - ("protein2", "KALTRAI"), - ("protein3", "KAAISQQ"), - ] - _, _, batch_tokens = batch_converter(data) - expected_tokens = torch.tensor( - [ - [ - [0, 20, 15, 11, 7, 10, 16, 6], - [0, 15, 5, 4, 11, 10, 5, 12], - [0, 15, 5, 5, 12, 8, 16, 16], - ] - ] - ) - assert torch.allclose(batch_tokens, expected_tokens) diff --git a/esm/tests/test_load_all.py b/esm/tests/test_load_all.py deleted file mode 100644 index d896029..0000000 --- a/esm/tests/test_load_all.py +++ /dev/null @@ -1,51 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -from pathlib import Path - -import pytest -import torch - -import esm - -# Directly from hubconf.py -model_names = """ - esm1_t6_43M_UR50S, - esm1_t12_85M_UR50S, - esm1_t34_670M_UR50S, - esm1_t34_670M_UR50D, - esm1_t34_670M_UR100, - esm1b_t33_650M_UR50S, - esm_msa1_t12_100M_UR50S, - esm_msa1b_t12_100M_UR50S, - esm1v_t33_650M_UR90S, - esm1v_t33_650M_UR90S_1, - esm1v_t33_650M_UR90S_2, - esm1v_t33_650M_UR90S_3, - esm1v_t33_650M_UR90S_4, - esm1v_t33_650M_UR90S_5, -""" -model_names = [mn.strip() for mn in model_names.strip(" ,\n").split(",")] - - -@pytest.mark.parametrize("model_name", model_names) -def test_load_hub_fwd_model(model_name: str) -> None: - model, alphabet = getattr(esm.pretrained, model_name)() - # batch_size = 2, seq_len = 3, tokens within vocab - dummy_inp = torch.tensor([[0, 1, 2], [3, 4, 5]]) - if "esm_msa" in model_name: - dummy_inp = dummy_inp.unsqueeze(0) - output = model(dummy_inp) # dict - logits = output["logits"].squeeze(0) - assert logits.shape == (2, 3, len(alphabet)) - - -@pytest.mark.parametrize("model_name", model_names) -def test_load_local(model_name: str) -> None: - # Assumes everything has already been loaded & cached. - local_path = Path.home() / ".cache/torch/hub/checkpoints" / (model_name + ".pt") - if model_name.endswith("esm1v_t33_650M_UR90S"): - return # skip; needs to get rerouted to specific instance - model, alphabet = esm.pretrained.load_model_and_alphabet_local(local_path) diff --git a/esm/tests/test_notebooks.py b/esm/tests/test_notebooks.py deleted file mode 100644 index fac8401..0000000 --- a/esm/tests/test_notebooks.py +++ /dev/null @@ -1,65 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import os -import subprocess -from pathlib import Path - -import pytest - -notebook_dir = Path(__file__).parents[1] / "examples" -notebook_fns = notebook_dir.glob("*.ipynb") - - -def convert_notebook_to_py(nb_fn: Path, py_fn: Path) -> None: - """ - From https://stackoverflow.com/questions/17077494/how-do-i-convert-a-ipython-notebook-into-a-python-file-via-commandline - """ - import nbformat - from nbconvert import PythonExporter - - with open(nb_fn) as fh: - nb = nbformat.reads(fh.read(), nbformat.NO_CONVERT) - - exporter = PythonExporter() - source, meta = exporter.from_notebook_node(nb) - - # Skip the magic, which gets converted to `get_ipython()` - source.replace("get_ipython", "# get_ipython") - - with open(py_fn, "w+") as fh: - fh.writelines(source) - - -def run_multiple(cmds): - for cmd in cmds.strip().split("\n"): - print(cmd) - subprocess.run(cmd.strip(), shell=True, check=True) - - -def do_setup(nb_name): - """Do any setup work; see intro of the notebook""" - if nb_name == "sup_variant_prediction": - cmds = """ - curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593_reprs.tar.gz - tar -xzf P62593_reprs.tar.gz - curl -O https://dl.fbaipublicfiles.com/fair-esm/examples/P62593.fasta - """ - run_multiple(cmds) - else: - print(f"No setup work for {nb_name}") - - -@pytest.mark.parametrize("nb_fn", list(notebook_fns)) -def test_run_notebook(nb_fn: Path, tmp_path: Path): - """Simply make sure the notebooks run from a-z""" - py_fn = tmp_path / (nb_fn.stem + ".py") - print(py_fn) - convert_notebook_to_py(nb_fn, py_fn) - os.chdir(notebook_dir) - do_setup(nb_fn.stem) - _globals = {} - exec(py_fn.read_text(), _globals) - # No asserts, just running is enough for now diff --git a/esm/tests/test_readme.py b/esm/tests/test_readme.py deleted file mode 100644 index a11fcf8..0000000 --- a/esm/tests/test_readme.py +++ /dev/null @@ -1,182 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import shutil -import subprocess -import sys -import tempfile -from pathlib import Path - -import requests -import torch - -import esm - - -def test_readme_1(): - import torch - - model, alphabet = torch.hub.load( - "facebookresearch/esm:main", "esm1b_t33_650M_UR50S" - ) - - -def test_readme_2(): - import torch - - import esm - - # Load ESM-1b model - model, alphabet = esm.pretrained.esm1b_t33_650M_UR50S() - batch_converter = alphabet.get_batch_converter() - - # Prepare data (first 2 sequences from ESMStructuralSplitDataset superfamily / 4) - data = [ - ( - "protein1", - "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG", - ), - ( - "protein2", - "KALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE", - ), - ( - "protein2 with mask", - "KALTARQQEVFDLIRDISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEE", - ), - ("protein3", "K A I S Q"), - ] - batch_labels, batch_strs, batch_tokens = batch_converter(data) - - # Extract per-residue representations (on CPU) - with torch.no_grad(): - results = model(batch_tokens, repr_layers=[33], return_contacts=True) - token_representations = results["representations"][33] - - # Generate per-sequence representations via averaging - # NOTE: token 0 is always a beginning-of-sequence token, so the first residue is token 1. - sequence_representations = [] - for i, (_, seq) in enumerate(data): - sequence_representations.append( - token_representations[i, 1 : len(seq) + 1].mean(0) - ) - - # Look at the unsupervised self-attention map contact predictions - import matplotlib.pyplot as plt - - for (_, seq), attention_contacts in zip(data, results["contacts"]): - plt.matshow(attention_contacts[: len(seq), : len(seq)]) - plt.title(seq) - plt.show() - - -def _run_py_cmd(cmd): - this_python = sys.executable - cmd.replace("python", this_python) - subprocess.run(cmd, shell=True, check=True) - - -def test_readme_3(): - # NOTE modification on copy paste from README for speed: - # * some_proteins -> few_proteins (subset) - # * I computed reference values a while ago for: esm1b -> esm1 and layers 33 -> 34 - cmd = """ -python extract.py esm1b_t33_650M_UR50S examples/some_proteins.fasta examples/some_proteins_emb_esm1b/ \ - --repr_layers 0 32 33 --include mean per_tok -""" - _run_py_cmd(cmd) - confirm_all_tensors_equal( - "examples/few_proteins_emb_esm1/", - "https://dl.fbaipublicfiles.com/fair-esm/tests/some_proteins_emb_esm1_t34_670M_UR50S_ref", - ) - - -def assert_pt_file_equal(f, fref): - a = torch.load(f) - b = torch.load(fref) - # set intersection of dict keys: - which_layers = a["representations"].keys() & b["representations"].keys() - assert which_layers, "Expected at least one layer appearing in both dumps" - for layer in which_layers: - assert torch.allclose( - a["representations"][layer], b["representations"][layer], atol=1e-3 - ) - - -def confirm_all_tensors_equal(local_dir: str, ref_dir: str) -> None: - # TODO use pytest built-in fixtures for tmp_path https://docs.pytest.org/en/6.2.x/fixture.html#fixtures - for fn in Path(local_dir).glob("*.pt"): - with tempfile.NamedTemporaryFile(mode="w+b", prefix=fn.name) as f: - ref_url = f"{ref_dir}/{fn.name}" - with requests.get(ref_url, stream=True) as r: - shutil.copyfileobj(r.raw, f) - f.seek(0) - assert_pt_file_equal(fn, f) - - -def test_msa_transformers(): - _test_msa_transformer(*esm.pretrained.esm_msa1_t12_100M_UR50S()) - _test_msa_transformer(*esm.pretrained.esm_msa1b_t12_100M_UR50S()) - - -def _test_msa_transformer(model, alphabet): - batch_converter = alphabet.get_batch_converter() - # Make an "MSA" of size 3 - data = [ - ( - "protein1", - "MKTVRQERLKSIVRILERSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG", - ), - ( - "protein2", - "MHTVRQSRLKSIVRILEMSKEPVSGAQLAEELSVSRQVIVQDIAYLRSLGYNIVATPRGYVLAGG", - ), - ( - "protein3", - "MHTVRQSRLKSIVRILEMSKEPVSGAQL---LSVSRQVIVQDIAYLRSLGYNIVAT----VLAGG", - ), - ] - batch_labels, batch_strs, batch_tokens = batch_converter(data) - - with torch.no_grad(): - results = model(batch_tokens, repr_layers=[12], return_contacts=True) - token_representations = results["representations"][12] - assert token_representations.shape == (1, 3, 66, 768) - - -def test_variant_readme_1(): - cmd = """ -python variant-prediction/predict.py \ - --model-location esm1v_t33_650M_UR90S_1 esm1v_t33_650M_UR90S_2 esm1v_t33_650M_UR90S_3 esm1v_t33_650M_UR90S_4 esm1v_t33_650M_UR90S_5 \ - --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ - --dms-input ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv \ - --mutation-col mutant \ - --dms-output ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv \ - --offset-idx 24 \ - --scoring-strategy wt-marginals - """ - _run_py_cmd(cmd) - - -def test_variant_readme_2(): - cmd = """ -python variant-prediction/predict.py \ - --model-location esm_msa1b_t12_100M_UR50S \ - --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ - --dms-input ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv \ - --mutation-col mutant \ - --dms-output ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv \ - --offset-idx 24 \ - --scoring-strategy masked-marginals \ - --msa-path ./variant-prediction/examples/BLAT_ECOLX_1_b0.5.a3m - """ - _run_py_cmd(cmd) - - -if __name__ == "__main__": - confirm_all_tensors_equal( - "examples/few_proteins_emb_esm1/", - "https://dl.fbaipublicfiles.com/fair-esm/tests/some_proteins_emb_esm1_t34_670M_UR50S_ref/", - ) diff --git a/esm/variant-prediction/README.md b/esm/variant-prediction/README.md deleted file mode 100644 index c140104..0000000 --- a/esm/variant-prediction/README.md +++ /dev/null @@ -1,31 +0,0 @@ -# Zero-shot variant prediction with protein language models - -This folder contains code and pre-trained weights for the ESM-1v models described in -[Language models enable zero-shot prediction of the effects of mutations on protein function. (Meier et al. 2021)](https://www.biorxiv.org/content/10.1101/2021.07.09.450648v1). - -### Labeling a deep mutational scan with model predictions - -Given a deep mutational scan and its associated sequence, the effects of mutations can be predicted using an ensemble of five ESM-1v models: -``` -python variant-prediction/predict.py \ - --model-location esm1v_t33_650M_UR90S_1 esm1v_t33_650M_UR90S_2 esm1v_t33_650M_UR90S_3 esm1v_t33_650M_UR90S_4 esm1v_t33_650M_UR90S_5 \ - --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ - --dms-input ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv \ - --mutation-col mutant \ - --dms-output ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv \ - --offset-idx 24 \ - --scoring-strategy wt-marginals -``` - -Similarly, one could use the MSA Transformer: -``` -python variant-prediction/predict.py \ - --model-location esm_msa1b_t12_100M_UR50S \ - --sequence HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW \ - --dms-input ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv \ - --mutation-col mutant \ - --dms-output ./variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv \ - --offset-idx 24 \ - --scoring-strategy masked-marginals \ - --msa-path ./variant-prediction/examples/BLAT_ECOLX_1_b0.5.a3m -``` diff --git a/esm/variant-prediction/__init__.py b/esm/variant-prediction/__init__.py deleted file mode 100644 index e69de29..0000000 diff --git a/esm/variant-prediction/examples/BLAT_ECOLX_1_b0.5.a3m b/esm/variant-prediction/examples/BLAT_ECOLX_1_b0.5.a3m deleted file mode 100644 index 82bd334..0000000 --- a/esm/variant-prediction/examples/BLAT_ECOLX_1_b0.5.a3m +++ /dev/null @@ -1,153366 +0,0 @@ ->BLAT_ECOLX/24-286 -hpETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Uncharacterized protein n=326 Tax=root TaxID=1 RepID=A0A077REW6_WHEAT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPD------------- ------------------------ ->[subseq from] Uncharacterized protein n=326 Tax=root TaxID=1 RepID=A0A077REW6_WHEAT ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005DE4B21 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAXS- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005DE4B21 ------------------------------------------------------------- ----ALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] BETA-LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0004437F73 ---ALNDEFAALEKQYGGRLGVYALDTGTGRTI-AYRADERFPMCSTFKALAAAAVLAQVD -AGKESLDRRITYTKDDLVDYSPVTEKHVGTGMTLAELCEAAITYSDNTAANLLLDEIGGP -KGLTAFLRSIGDDVTRLDRWEPELNEALPGDPRDTTTPAAMAATLRALLLGDALSPASRA -QLTDWMRGNTTGDKLIRAGLPAGWRVGDKTGTGSYGTRNDIAIIWPPNRAPIVLAIYSTG -STADAKERNALIAEAAKIVAE-- ->[subseq from] BETA-LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0004437F29 ---ALSEQLAELEKRSGGRLGVAVLDTATGRRI-AYRGDERFPMCSTFKALLAAAVLAQVD -QGKERLDRRITYSKADLVDYSPVTEKHVGGGMTVAELCEAAITYSDNTAANLLLEALGGP -AALTAFLRSIGDEVTRLDRWEPELNEALPGDPRDTTTPRAMAATLRKLLLGDALSPASRE -QLVDWLLANKTGDKRLRAGLPADWRVGDKTGTGGHGTTNDIAVIWPPNRAPIVVAVYYTE -SQADAEARDAVIAEVGRLVAEAf ->[subseq from] GNCA BETA LACTAMASE n=2 Tax=synthetic construct TaxID=32630 RepID=UPI000957C7BE ---QLSEQLAELEKRSGGRLGVAVLDTATGRRI-AYRGDERFPMCSTFKALLAAAVLARVD -QGKERLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITLSDNTAANLLLEALGGP -AALTAFLRSIGDEVTRLDRWEPELNEAAPGDPRDTTTPAAMAATLRTLLLGDALSPASRQ -QLVDWLVANKTGDKRLRAGLPADWRVGDKTGTGGHGTTNDIAVIWPPGRAPIVVTVYLTE -SQVDADARDAVIAEVGRLVVEAf ->[subseq from] GNCA4 LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0009468CF7 ---ALSEQLAELEKRSGGRLGVAVLDTATGRRF-GYRGDERFPMCSTFKALLAAAVLARVD -QGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGP -AALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQ -QLVDWLIANKTGDKRLRAGLPADWRVGDKTGTGEHGTTNDIAVIWPPNRAPILVAVYLTE -SQVDADARDAVIAEVARLVVAAf ->[subseq from] GNCA LACTAMASE W229D n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0007A93677 ---QLSEQLAELEKRSGGRLGVAVLDTATGRRI-AYRGDERFPMCSTFKALLAAAVLARVD -QGKERLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITLSDNTAANLLLEALGGP -AALTAFLRSIGDEVTRLDRWEPELNEAAPGDPRDTTTPAAMAATLRTLLLGDALSPASRQ -QLVDWLVANKTGDKRLRAGLPADDRVGDKTGTGGHGTTNDIAVIWPPGRAPIVVTVYLTE -SQVDADARDAVIAEVGRLVVEAf ->[subseq from] GNCA4 LACTAMASE W229D AND F290W n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0009388698 ---ALSEQLAELEKRSGGRLGVAVLDTATGRRF-GYRGDERFPMCSTFKALLAAAVLARVD -QGKENLDRRITYGKEDLVDYSPVTEKHVGDGMTVAELCEAAITYSDNTAANLLLEALGGP -AALTAFLRSIGDNVTRLDRWEPELNTAAPGDPRDTTTPAAMAATLRTLLLGDVLSPASRQ -QLVDWLIANKTGDKRLRAGLPADDRVGDKTGTGEHGTTNDIAVIWPPNRAPILVAVYLTE -SQVDADARDAVIAEVARLVVAAw ->[subseq from] Beta-lactamase n=41 Tax=root TaxID=1 RepID=Q52089_9ZZZZ ------------------------------------------------------------- ----------------------------LADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=UPI000D1B824A ----AAQMFAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTQADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPPAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIALAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Burkholderia TaxID=32008 RepID=F0GIV5_9BURK ----AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLVEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) TaxID=271848 RepID=UPI000980150C ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRL------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=A0A1B4I592_9BURK ----AAQMFAELERSAGGRVGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYSQADLVNYSPVSEKHVGTGMTVAALCEAAIQYSDNSAANLLLKMLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPPAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRTPIALAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007593DDF ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLCAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9131 TaxID=2184571 RepID=A0A3N8AB34_9BURK -----ATSFAALERAAGGRLGVCAIDTAGGRRV-QHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVAVAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAAARIAVATf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000CEBB9BD ---ALADMCARLEAGSGGRLGVCVLDTASGRMI-GHRLDERFPMCSTFKALAAGLVLARVD -RKQENLDRRVSYAKSDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA -QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPPQRAPLIVTVYLTG -ATVSRDQQNKIIADVGAAVAD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000757D79E ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075C4B1B ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000F50CFCC ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DC2EFD ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DEF938 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSLGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0004F8B564 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075679A2 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSA -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVTWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFD2CD ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00CCF5 ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans CGD1 TaxID=513051 RepID=B9AYU4_9BURK ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSO22-1 TaxID=716789 RepID=A0A2U1WMN1_9PROT ---DLGGTLAALEKRIDARLGVAVLDTATGRSW-GHRADERFPMCSTFKALACGAVLARVD -EGKERLDRRVRYTAGDLVTYSPATKEGVGAGMTVAEICEAAMTLSDNTAANLILDSLGGP -VALTAFVRSLGDAVTRLDRRETELNTAIPGDPRDTTTPAAMAGSLRALAVGDHLSASSRE -QFNAWMVATRTGDARLRAGLPKDWRIGDKTGTGDHGTANDVAVIWPPGRKPLVVSVYVTQ -TKASLDDRNAAIAEVGRLV---- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cepacia complex TaxID=87882 RepID=A0A087NXY8_BURPY ---AAAAALAHLERDAGGRLGVCAIDTASGRRV-AHRAAERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVTEKHVGAGMTVAELCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQ -ARADARAKDDVIADVARVVVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DE8F05 ------ASFAALEREAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIA---- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000F582E9A -----ATSFAALERAAGGRLGVCAIDTAGGRRV-QHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVAVAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075ABC6A -----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -TRADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI001248539F -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0006C7CDCB ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLCAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A125K4J2_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1Y1BME3_9BURK ----AAATFAQLERDAGGRLGVCAIDTASGRRV-AHRADERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVTGKHVDAGMTVAELCEATIQYSDNAAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPTRAPIVLVVYYTQ -AHADARAKDDVIADVARVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132E9M4_9BURK ----AYDALQALERDAGGRLGVYAIDTASGRSV-AYRPNERFPFCSTFKAMLGAAVLAQSV -ARPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLVEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAHAKDDVIAAVARIVAAAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia GG4 TaxID=1009846 RepID=J7J6R5_BURCE -----ATTFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYGQSDLVNYSPVSGKHVGTGMTVAELCAAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLHALTLGEALPPAQRA -QLVAWLRGNQVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKPKDDVIAAAARIAAATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A3P0CDT7_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. JP2-270 TaxID=2217913 RepID=A0A2U9SSR5_9BURK ---AAAATFADLERDAGGRLGVCAIDTASGRRV-AHRAAERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVTEKHVGVGMTVAELCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQ -ARADARAKDDVIADVARVVVAAf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3R9BAB6_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRII-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Caballeronia arationis TaxID=1777142 RepID=A0A158C2S8_9BURK --qSAASQLKALEAASNGRLGVAALNTGDGAIV-NYRADERFPFCSTFKVLLASAILTRSA -HEDGLLDQRIRYTQSDLVNYSPVSEKHVADGMTVAELCAAAIQYSDNSAANLLIRLLGGP -PAVTAFARSIGDDEFRLDRMETELNTAIPGDLRDTTTPAAMARSLQRLALGNALGARERD -QLQAWMRGNTTGDARIRAGVPRDWQVADKTGTGDYGTSNDVAVLWPPSKPPIVVVIYFTQ -REQDAKARSDVLASAAKIVARKf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007526BF2 ------ASFAALEREAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRVA---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. BR0M22 TaxID=2269369 RepID=UPI0013DF4E0D ---ALSEPCARLEAESGGRLGVGVLDTASGRTI-GHRLDERFPMCSTFKVLAAGLVLARVD -RKQESLDRRVSYAKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP -AGLTTFARSLGDDTTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA -QLITWLKANTTGGTRLRAGVPTGWTVGDKTGTGDRGTANDVAVIWPPQRAPLIVTVYLTG -ATVARDQQNKIIADVGAEVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3Q9FEF4_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075FFF57 ----AGQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia (strain AU 1054) TaxID=331271 RepID=A0A0H2XVR0_BURCA ----AATTLADLERDAGGRLGVCAIDTASGRII-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGGYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sacheonensis TaxID=443615 RepID=UPI0013D0C5DC ---DANSRLQALESVHGGRLGVSIFDTGTGKRI-GHRADERFPMCSTFKFLAAAQVLARVD -RGEERLDRRVVYTKDDLVAYSPVTEKHVGTGMTLAELCHATVTVSDNTAGNLLLASFGGP -AGLTAFARSLGDGVTRLDRWETELNEAVPGDPRDTTSPAAMLEDMRSLLLGDTLSPASRK -QLADWLVATTTGDKRIRGGLPKEWRAGDKTGTSNNGVTNDIAIVWPPGRAPLLVTAYYAE -YPQPQEARNAVIAEVGRIAA--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF887E ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV -EHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075ACFD5 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007593C38 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000757E74C -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007537933 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=A0A1B4C0W4_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLEQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132EYV1_9BURK ----AYDALQALEREAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLVQWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFC82A ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRMLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAIS-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F59FBBC ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075F42DC -----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5ACA6B -----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075A852B ------TSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI00075D8726 ----AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLLEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI000841559E ----AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLLEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] Beta-lactamase n=2 Tax=Halomonas muralis TaxID=119000 RepID=A0A1G9S152_9GAMM ----LLEKLVEIEERLDARIGVAVLDIQTGRRW-EYRADERFPMTSTFKALACGAVLARVD -AGQEDLDRRIRIEASDIVTYSPVTENHVGEEMTLGELCKATITTSDNTAGNLILETLDGP -SGVTEFARSLGDSMTRLDRWETELNEATPGDPRDTTTPNAMTANLHKLVLGDTLSQQSRD -QLTTWLVANKTGDEKLRAGLPNDWRVGDKTGGGNHGTTNDVAVIWPPGREPLIVSVYITQ -TKASVDERNAAIADIGRAIH--- ->[subseq from] class A beta-lactamase n=1 Tax=Microvirga massiliensis TaxID=1033741 RepID=UPI00062B5C0E ---DLSREIARIESGLEARLGVAVLDTATGQRM-SHRGSERFPMCSTFKMLACAAVLRRVD -AGQEDLERRIRFGASDVVTYSPVTKDRVGDGMTLAELCEAAMTQSDNTAGNLILKTLGGP -SGVTTFARSLGDLVTRLDRWETDLNEAAPGDPRDTTTPDAMTANLHSLAVDNGLSPQSRD -QLTAWLVANKTGDARLRAGLPKNWRIGDKTGSGERGTANDVAVIWPPQRKPLIVSVYLTE -TKASSDERNAAIAEIGRAV---- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI000754056F ----AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLVQWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075D3B85 -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075BA194 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGNALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKARDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00098187F9 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075B6A1E -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU18528 TaxID=2015350 RepID=A0A2G1SC76_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5B275B ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -GRPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIAVAVYYTQ -ARADARSQDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=A0A323UF44_RHOPL ---ALADRCARLEADSGGRLGVGVLDTASGRIV-GHRLDERFPMCSTFKVLAAGLVLSRVD -RKQESLDRRVSYTKSDLVTYSPATEKHIEGGMTIAELCAAAITLSDNTAANLLLGSFGGP -AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDTLSPTSRA -QLIAWLKANTTGGTRLRAGVPAGWTVGDKTGTGDRGTANDVAVLWPPQRAPLIVTVYLTG -ATAARDQQSAIIAAVGAAVATKw ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9D8P5_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075A009B -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981E40D ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans CF2 TaxID=985078 RepID=J4JN58_9BURK ------ASFAALERAAGGRLGVCAIDAATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDEVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. HAN2018 TaxID=2233539 RepID=UPI000E649071 ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A2Z5MZZ9_BURPY ----AAAALADLERDAGGRLGVCAIDTASGRVV-EHRANERFPFCSTFKTMLSAAVLAQSV -ERPGLLQQRVTYGKADLVNYSPVTEKHVGAGMTVAELCAAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTAVPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWPTSRAPIVLVVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A1W0YMY5_9BURK ------ASFAALERAAGGRLGVCAIDAATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. NFACC38-1 TaxID=1566268 RepID=A0A1H9YVQ3_9BURK ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5E9EFD ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075BB301 ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075CFA54 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWSPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0008913132 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAILSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. USM B20 TaxID=1571773 RepID=A0A4R9MJE6_9BURK -----ATSFAALERAAGGRLGVCAIDTAGGRRV-QHRADERFPFCSTFKAMLGAAVLAQSV -ERPGLLQQRVDVAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLMLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVAMf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia dolosa TaxID=152500 RepID=A0A345IT63_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSI -AQPALLQQRVAYGKADLVSYSPVTEQHVGAGMTVAELCAATIQYSDNTAANVLMKLIGGP -QAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRALMLGDALPSAQRA -QFVEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVAWPPSGAPIVLAVYYTQ -ARADARAKDDVIAAAARIAV--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075B6772 ---AAEATFADLERDAGGRLGVCAIDTTSGRII-GHRSGERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNAAANLLMKLLGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007579C92 ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWLPSRVPIAVAVYYTQ -TRADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A103ZRW5_BURCE ---AAEATFADLERDAGGRLGVCAIDTTSGRVI-GHRSGERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNAAANLLMKLLGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075D0CBC -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPGQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075AEF6D -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1072 TaxID=1637871 RepID=UPI000756D485 ----AATTLADLERDAGGRLGVCAIDTASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVGALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRALTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TQADARAKDDVIASAARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. CF125 TaxID=1855303 RepID=A0A1H1H9J1_9GAMM ----ASGRLQALESLHGGRLGVSILDTGTGKRI-GHRADERFPMCSTFKFLAAAQVLSRVD -RGEERLDRRIVYAKDDLVAYSPVTEKHVATGMTLAELCRATITVSDNTAGNLLLASFGGP -AGLTRFAQSLGDSVTRLDRWETELNEAVPGDPRDTTSPAAMLDDMRSLLLGDTLSPASRK -QLTDWLIATTTGDKRIRGGLPKEWRAGDKTGTSNNGVTNDIAIVWPPGRAPLLVAAYYAE -YAQPKEARNAVIAEVGRIAA--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. BE17 TaxID=2656644 RepID=UPI00128C859B ---AAAAALAELERDAGGRLGVCAIDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVTEKHVGAGMTVAELCEATIQYSDNAAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -RLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDVGVVWSPSRAPIVLAVYYTQ -AHADARAKDDVIADVARVVVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075CC449 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI000757EE5F -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPSAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=C1J897_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRII-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTVYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI0007689856 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sp. OV555 TaxID=2135497 RepID=A0A2U0WHG1_9BURK --qSAASQLKALEAASNGRLGVAALNTADGAIV-NYRADERFPFCSTFKVLLASAILTRSA -HEDGLLDERIRYTQSDLVNYSPVSEKHVADGMTVADLCAAAIQYSDNSAANLLIRLLGGP -SAVTAFARSIGDDEFRLDRTETELNTAIPGDLRDTTTPAAMLRSLQRLALGNALGARERD -QLQAWMRGNTTGDARIRAGVPRDWQVADKTGTGDYGTSNDVAVLWPPSKAPIVVVIYFTQ -REQDAKARSDVLASAAKIVAGKf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00E009 ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPLAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=4 Tax=Burkholderia cepacia complex TaxID=87882 RepID=O08350_BURCE ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAANLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAATRIA---- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075A62A8 -----ATSFAALERAAGGRLGVCAIDTASGRQA-WHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFE03F ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGQSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0008F4C1E3 ------QMLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5AE451 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTRADLVSYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5AA01F -----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -TRADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium erythrophlei TaxID=1437360 RepID=A0A1M5I8Q3_9BRAD --dNLAKELARLEAESGGRLGVAVLDTSTGAMA-GHRADQPFPMCSTFKVLAVAAILRRVD -AQGEKLERRIGFTKADLVSYSPVTERHLGGDMSLAELCEAAITRSDNTAANLLLANIGGP -ANLTAFVRTLGDQVTRLDRIEPELNEATPGDPRDTTTPNAMLSNLQKLVLGEVLSSASRD -RLTAWMIGNKTGDARLRAGLPAGWRVGDKTGSGARGTANDVAVIWPAERAPVIVAVYLTG -ASGSNDQQNATIAAVARAVS--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9LQS6_9BURK ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000CE1C5BC ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A109EHH5_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075BE4BE ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0067BB ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A286P6D6_9BURK ------QVLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRALMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALVVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A088V0N6_9BURK ----AYDALQALEREAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLLEWLRGNKVGDKRIRAGVLAGWQVGDKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F59E2C4 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A2S9M8Z7_9BURK ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFA5EF ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFRFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5AC330 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVKYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARARDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=UPI00080B0DFA ----AAATFAQLERDAGGRLGVCAIDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVTGKHVDTGMTVAELCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDSTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIVLVVYYTQ -AHADARPKEDVIADVARVVVE-- ->[subseq from] ENCA BETA-LACTAMASE n=1 Tax=synthetic construct TaxID=32630 RepID=UPI0002B63CCF -hpQTLEQIKESESQLSGRVGMVELDLASGRTL-SYRADERFPMMSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVEYSPVTEKHLADGMTVAELCAAAITMSDNTAANLLLATIGGP -AGLTAFLRNIGDNVTRLDRWETELNEALPGDERDTTTPAAMAATLRKLLTGEILSAASRQ -QLITWMVADKVAGPLLRSVLPAGWFIADKTGAGERGSRGIIAVLGPDGKPSRIVVIYLTE -TQASMDERNQQIAEIGAALIEHw ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00051017C5 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPEAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A318I1A7_BURPY ---AAAATLAHLERDAGGRLGVCAIDTASGRRV-EHRAAERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKPDLVNYSPVTERHVGAGMTVAELCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLALGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWAPSRAPIVLAVYYTQ -ARADARAKDDVIADVARVVVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000752B602 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF6BDD ------ASFAALERAAGGRLGVCAIDAATGRRA-LYRADERFPFCSTIKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDEVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EF9387A ------------------------------------------------------------- -----------HYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0011CBDCC9 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQFSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia (strain MC0-3) TaxID=406425 RepID=B1K831_BURCC ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRMRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00075D1824 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075D02CA -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRVPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075DBE4C -----ATSFAALERAAGGRLGVCAIDTASGRQA-WHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRT -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075CDA08 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLATWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A0G3WX80_BURPY ----AAATFAQLERDAGGRLGVCAIDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVTGKHVDTGMTVAELCEATIQYSDNAAANLLMKLIGGP -SAVTAYARSIGDSTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIVLVVYYTQ -AHADARPKEDVIADVARVVVE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. BE12 TaxID=2082394 RepID=UPI000CF47F45 ----AAATIADLERDAGGRLGVCAIDTASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSGKHVGTGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWEPELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPTGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia complex TaxID=87882 RepID=UPI00075956FD ----AATTLADLERDAGGRLGVCAIDTASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVGALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRALTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -AQADARAKDDVIASVARIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0003F9130F ----AAATLADLERDAGGRLGVCAIDAASGRAI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGTGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA -QLITWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0011ABBE23 -----GQTLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=C1J8A0_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00075456EF -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEATIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDHGTTNDAGVIWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075C42E3 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0009E0F836 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans CGD2 TaxID=513052 RepID=B9BS30_9BURK ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVMWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0009E0DC2B ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVMWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D004034 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007529BB0 ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -TRADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F60014C ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -TRADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia dolosa AU0158 TaxID=350701 RepID=A2WFY8_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSI -AQPALLQQRVAYGKADLVSYSPVTEQHVGAGMTVAELCAATIQYSDNTAANVLMKLIGGP -QAVTAYARSIGDATFRLDRWETELNTALPGDPRDTTTPAAMAASLRALMLGDALPSAQRA -QFVEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVAWPPSGAPIVLAVYYTQ -ARADARAKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU28863 TaxID=2015352 RepID=UPI000B79F216 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRASERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0008416FCA -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia reimsis TaxID=2234132 RepID=A0A365QZ51_9BURK ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000754EE01 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000277CA0F ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE6CDA ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D002920 ------ASLAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU17457 TaxID=2015349 RepID=UPI000B79F483 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRASERFPFCSTFKAMLSATVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. LA-2-3-30-S1-D2 TaxID=1637862 RepID=A0A1B4ETC7_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. HI2761 TaxID=2015360 RepID=A0A228QA03_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGTGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPTGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5B5EBD ----AAAMLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0006AC9657 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAILSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F594E81 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSGKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A1V2XBA9_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00078BCEFD ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI00075C46CE ----AYDALQALERDAGGRLGVYAVDTASGRSV-EHRPNERFPFCSTFKAMLAAAVLAQSV -ERPALLQQRVTYGKADLVNYSPVSGKHVDTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -LAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLALGDALPAAQRA -QLVEWLRGNKVGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -ARADARAKDDVIAAVARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. CCA53 TaxID=1776288 RepID=UPI00080B1005 ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A104LDA2_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -EQPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVAWLRCNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075BC7C7 -----GQMLAELESSLGGRLGVCAIDTASGRVI-THRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075F4877 ------EMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981D5D7 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGGYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N8ZSQ1_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRASERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLTLGDALPAAQRA -QFVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFB513 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000753509D ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. ABCPW 11 TaxID=1637859 RepID=A0A103B6S2_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVGALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRALTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -AQADARAKDDVIASAARIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D3338AF ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGAYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A107PQ27_BURCE -----GQMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVHAf ->[subseq from] PenA family class A beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0002344058 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVTQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU6039 TaxID=2015344 RepID=A0A228PHG2_9BURK ------QMLAELERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTRADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F599506 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007580E34 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000759EE17 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000751FEB7 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVIQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F564DF1 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVAYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMATSLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=B8R6A5_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000484E52E -----AATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTRADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas duriflava TaxID=459528 RepID=A0A562QL37_9PSED ---ATEQRLARLEQELNGRLGVFAWDTGAGTVL-RYRADERFPMNSTFKVMLAAAILAQNE -KAHGLLEQHIRYTEHDLVTYSPITEKHLAQGMTIAELCAAAIQYSDNTAANLLMAHLGGP -AAVTAFARSIDDEMFRLDRWETELNTAIPGDPRDTSTPEAMGYSLQRLALGDALSAASRE -QLQAWLRGNTTGNTRIRAGVPSDWQVGDKTGTGDYGTASDIAVLWPPGRAPMIIAIYTAQ -TEPTAKARNDVIASAARVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000C9B0EE5 ----LTQRFAELEKQLDARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYTADDLVTYSPVTERHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDHHTRLDRWETELNEASPGDPRDTTTPAAMAANLQRLVLGDSLSAASRE -QLVAWMLASQTGAAKLRAGLPPGWRIGDKTGSGERGTTNEVAVIWPPQRKPVIACVYLTQ -TQASADARNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A4S3HX95_BURCE ------QMLAELESSVGGRLGVCAIDTASGRVI-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9004 TaxID=2184559 RepID=A0A3P0SIV7_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIALATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0007542FCB ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF9303 ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A5P2K0U9_9BURK ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000841C7DB ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVMWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008418F4E -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALLTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDEAFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -AHADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. SRS-25 TaxID=2094190 RepID=A0A4R4C1P1_9BURK ----AAQMLAELERSAGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007558954 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1826 TaxID=1637875 RepID=UPI000751FFF9 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A1V2VWQ1_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE5840 ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDRRIRAGVPTGWRVGDKTGTGDYGTTNDVGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075FAEB1 -----ATSFAALERAAGGRLGVCAIDTASGRQA-WHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F596C46 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAAYYTQ -TRADARAKDDMIASVARIVAQTf ->[subseq from] Beta-lactamase enzyme family n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A5P8VE29_BURCE ------QMLAELESSVGGRLGVCAIDTASGRVI-THRADERFPFCSTFKAMLSAAVLAQSV -ARPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMELLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000752C178 ------ASFAALERAAGGRLGVCAIDTGTGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPEAMAASVRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000665F193 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVTQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU16741 TaxID=2015347 RepID=A0A228HKA1_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSERHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -PAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDVGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000E5AECEA ---ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD -RKQEKLDRRVSYAKADLVTYSPATEKHVEDGMTIAELCKAAITLSDNTAANLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA -QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPPQRTPLIVTVYLTG -ATVVRDQQNKIIADVGAAVAD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F59A2C7 ----AAQMLAELERSVGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. YR577 TaxID=1884373 RepID=A0A1I7EDY1_9RHIZ ---DAAAQLRALEKKYGGRLGVAILDTASGTRI-EHRADERFALCSTFKVLASAAVLARVD -KGEEKLDRRITYEKKDLVTYSPVTEKHVGKKMTLAELCEAAITLSDNTAGNLLLASFGGP -AGLTAYARTLGDEVTRLDRIETALNEAKTGDPRDTTTPAAMLADLQKLVLGDALSPASRD -QLKTWLLANKTGDKRLRAHLPKDWKVGDKTGTGDNGSANDVGILWPPKRGPIIVSSYFTE -SSASTDEKNIVHAEVGRIAA--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00084673D7 ----AAATLADLERDAGGRLGVCAIDTASGRDI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A4Q2AEF3_9BURK ------TSFDALERAAGGRLGVCAIDTASGRRA-LYRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYGKADLVKYSPVSEKHVDTGMTVADLCAAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGEALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIVLTVYYTQ -TRADARAKEDVIAAATRIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000CFFA38B ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A498RWF3_9BURK -----AAALADLERDAGGRLGVCAIDTASGRSV-EHRPNERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYSKADLVNYSPVTEKHVDTGMTVAAMCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARSKDDVIASAARIVARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI00064F0B97 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYTRSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000759AFC1 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAEWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00048637BA ----AATTLADLERDAGGRLGVCAIDTVSGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDEAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075C4E24 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075F0500 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -EQPGLLQQRVTYTKADLVNYSPVSEKHVGAAMTVAALCEATIQYSDNSAANLLMKLVGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRE -QLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A095EC36_BURCE ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAEWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D004F65 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELKTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F56F5CB ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTRANLVSYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0008417161 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSGKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007B7E3C8 -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRICAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] class A beta-lactamase n=1 Tax=Acidobacteriaceae bacterium KBS 89 TaxID=1267534 RepID=UPI00035F7867 --dQLNRELEKIEAASGGRLGVAILDTATGARI-LHRGDERFPMCSTFKLVACAAVLAKVD -AGKQRLDQRIIFQKTDLVTYSPITQTHTGAPMTLGEICAAAIDYSDNTAANLILDNLGGP -AGFTQFARSIGDPVTRLDRIETALNESLPNDPRDTTTPSAMVTNLNSLLLGSALSPPSRD -QLTQWLLANTTGGTRLRAGVPATWRVGDKTGTGDQGSTNDIGILWPPNAKPILVCVYLTG -TKASADERNATIASVGRAVAA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5A3E13 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTAPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU31280 TaxID=2015353 RepID=UPI000B7A20FB ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAAERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAHARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -ARADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A095DJB8_BURCE ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLARSV -ERPGLLQQRVTYTQADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A1V6L286_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRTPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia JBK9 TaxID=1395570 RepID=A0A0U4CD75_BURCE -----VAAFADLERNAGGRLGVCAIDTASGRRI-EHRSGERFPFCSTFKAMLSAAVLAQSV -DRPGLLQQRVTYTRADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGEALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPASRAPIVLVVYYTQ -TQADARAKDDVIASVARIVAQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A3P0WRM2_BURCE ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTFTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE9097 ------ASFAALERAAGGRLGVCAIDAATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0003C47E21 ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAALLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAAYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. AU31652 TaxID=2015354 RepID=UPI000B79D645 ------QMLAELERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTQADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000980ED6A ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNLAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVTQTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. FL-7-2-10-S1-D7 TaxID=1637866 RepID=A0A103L2Y5_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRLA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGEALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0009E0E129 ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. NRF60-BP8 TaxID=1637853 RepID=UPI00075C3F3B ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASAARIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A2X1GQN3_BURCE ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000751F368 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BCEE6 -----ASSLAELERAAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI00124683C5 -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVSTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPDAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000C9C0815 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNLAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGGYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVTQTf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EF7B767 ------------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000759A109 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSREPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=A0A103KF24_9BURK ----AAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV -DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAEQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARAKDGVIASVAQIVARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. 28_3 TaxID=2183921 RepID=A0A364GRC7_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00078B40E7 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAFTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVTQTf ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain TIE-1) TaxID=395960 RepID=B3Q9A2_RHOPT ---ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD -RKQEKLDRRVSYAKSNLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSPASRA -QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGSRGTANDIAVLWPPQRAPLIVTVYLTG -ATVVRDQQNKIIADVGAAVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1D7ZLC0_9BURK -----AAALADLERDAGGRLGVCAIDTASGRIV-EHRPNERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYSKADLVNYSPVTEKHVDTGMTVAAMCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARSKDDVIASAARIVARAf ->[subseq from] Beta-lactamase n=1 Tax=Caballeronia telluris TaxID=326475 RepID=A0A158IF65_9BURK --qSAASQLKALEAASNGRLGVAALNTGDGAIV-NYRADERFPFCSTFKVLLASAILTRST -HEDGLLDQRIRYTQSDLVNYSPVSEKHVADGMTVAELCAAAIQYSDNSAANLLIRLLGGS -SAVTAFARSIGDDEFRLDRTETELNTAIPGDLRDTTTPAAMLRSLKRLALGDALGARERD -QLQAWMRGNTTGDARIRAGVPLDWQVADKTGTGDYGTSNDVAVLWPPSKAPIVVVIYFTQ -REQDAKARNDVLASAAKIVAGKf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9FPW0_9BURK ----AATTLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTRADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWAVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQ-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007574A9F -----ASSLAELERTAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A105VSS3_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVPIAQSDLVNYSPVSGKRVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVARf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A3N7PT91_9BURK ------TSLTELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALLTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCAATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. HI2500 TaxID=2015358 RepID=UPI000B7A6289 ------QMLAELERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEATIQFSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. D-99 TaxID=2717316 RepID=UPI001424218F ------QMLAELESSVGGRLGVCAIDIASGRVV-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVDEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASVRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQ-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A2S5E6M4_9BURK ------QMLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMASSMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWTPSGAPIALAVYYTQ -ARADARAKDDVIASAARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119M6D0_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALLTQRVTYRQADLPEWSPVTEKHVDTGMTVDELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -AHADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI000F5A1168 ----AAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV -DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARAKDGVIASVAQIVARTf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1Z3Z1E8_BURCE ------QMLAELESSVGGRLGVCAIDTASGRII-EHRADERFPFCSTFKAMLSAAVLAQSV -GRPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -TRADARSKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075AEE21 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C6714 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5EAD20 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSREPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D1EBD -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPEPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A0J5X269_BURCE ------TSFDALERAAGGRLGVCAIDTASGRRA-LYRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYGKADLVKYSPVSEKHVDTGMTVADLCAAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWPPSRAPIVLTVYYTQ -TRADARAKEDVIAAATRIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104TUA0_9BURK -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007568858 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLLGNKTGDKRIRAGVPKGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007546CA6 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFC6A7 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPLAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C52CA -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI00066611A5 -----AAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV -DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARAKDGVIASVAQIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000755ECD6 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQHA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007530F3C -----ASSLAELERAAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATARYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981E96F ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTVLPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754E1B7 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDVRDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B8320 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BE8E6 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075A9809 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPGGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007551BAE -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B2224 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0006256D8D ----AAQMLAELERSAGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSMB1835 TaxID=1637876 RepID=A0A104CLD7_9BURK -----ATMLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLVVYYTQ -TRADARAKDDVIASVARIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754A9DF -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A3N8QH59_9BURK ----AAQMLAELERSVGGRLGVCAIDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMCGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119UZC5_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007594A10 -----ASSLAELERAAGGRLGVHVLDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000667E7C6 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKLGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVTQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000760749A -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075502FE -----ATSFAELERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVNYSPVSGKHVGAGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTSPAAMAASMRVLTLGDALPPVQCA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007551A4B -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDVGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EBA14 -----ASSLAELERAAGGRLGVHALDTATGRHV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007541252 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKREDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D000495 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FBE38 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752C89F -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A2S9NIW3_9BURK ------QVLAELERSAGGRLGVCAIDIATGRRA-EHRTDERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPDDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000757259D ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGRPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00DD56 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT -QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI00084F61AB ---AAAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAAVLAQSV -DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARAKDGVIASVAQIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F0E0D -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFAQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007529B65 -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F8A55 -----ASSLAELERATGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLGWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BBE5D -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0013F46BA1 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLRQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPSDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075397B4 -----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAQSA -ARPALLARHVMYRQADLVGWSPVTEKHVDAGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKGRDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A108CUI1_9BURK -----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAQSA -ARPALLARHVMYRQADLVGWSPVTEKHVDAGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKGRDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=C1J899_9BURK ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTVYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00AF05 ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRAGERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETEPNTALPGDLRDTTTPEAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. HI2714 TaxID=2015359 RepID=A0A228QUB7_9BURK ------QMLAELERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPVALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007583503 -----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAQSA -ARPALLARHVMYRQADLVGWSPVTEKHVDAGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKGRDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0005D785D7 -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000DC5441C ------QMLAELESSVGGRLGVCAIDTASGRVI-THRADERFPFCSTFKAMLSAAVLAQSV -GRPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRVPIAVAVYYTQ -ARADARSKDDVIASVARIVVQAf ->[subseq from] Beta-lactamase n=1 Tax=Halomonas anticariensis (strain DSM 16096 / FP35) TaxID=1121939 RepID=S2KQ94_HALAF --dELSRKLTEIEERLRARMGIAILDTETQRQW-TQRADERFPMCSTFKLLASAAVLTRVD -AGQEDLNRRIRFEASDVVTYSPVTEHRVGGEMTLAELCEAALTMSDNTAGNILLESLGGP -SGVTEFARSLGDSMTRLDRWETELNEAIPGDPRDTTTPAAMTANLRSLILGDRLSQTSRD -QLTTWLVSNKTGDARLRAGLPTNWRIGDKTGGGEYGTTNDVAVIWPPSRKPLIVSVYITE -TEASFDDRNAAIADVGRAV---- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E8C87 -----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075CF839 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRT -QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. EAR18 TaxID=2518972 RepID=UPI00109CCD6D ----FGERLADLESRLDARIGVAVLDTQTGLRW-GYRADERFPMSSTFKVLACGAVLARVD -AGKESLDRRLRFEAGDLVTYSPVTEHRTGGEMTLAELCEATITTSDNTAGNLILGTLGGP -AGLTDFMRTLGDDATRLDRWETALNEATPGDPRDTTTPRAMTDSLHALLLGDRLSPSSRE -RLIDWLVANQTGDAKLRAGLPEGWRIGDKTGGGGHGTNNDVAIIWPPGRQPAIVSVYLTG -SQADFEARNAAIADVARAL---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8992 TaxID=2184554 RepID=A0A3N8I6T0_9BURK ------AALADLERDAGGRLGVYAIDTARGRVV-EHRSGERFPFCSTFKAMLSAAVLAQSV -DRPGLLQQHVTYTQADLVNYSPVSGKHVGTGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGEALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARAKDDVIASVARIVAQTf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CI-41S TaxID=2511167 RepID=UPI0010B437D7 --qRLQQAFSRIEQDTGGRLGIAALDTESGLRA-SLRGDERFPMCSTFKALASAAVLRRVD -RGESSLDQRVRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMLLREIGGP -EGLTSFFRAIGDNVSRLDRWELALNEAVPGDPRDTTSPTAMLKNLQRVLLGDALSATSRK -TLTDWMVANKTGDARLRAGVPADWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ATAPADKCNEAIASVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. Chol1 TaxID=440512 RepID=K5YH17_9PSED ----LTQRFAELEKQLDARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYSADDLVTYSPVTERHVNDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFTRTLGDRHTRLDRWETELNEASPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD -QLIGWMLASQTGAAKLRAGLPQGWRIGDKTGSGERGTTNEIAVIWPPQRKPLIACVYLTQ -TQASADARNAALAAIGRALAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rugamonas sp. FT29W TaxID=2660639 RepID=A0A6A7N753_9GAMM ------ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP ----ALLKKRVAYRKSDLVAYSPITEQHVGKGMTVAALCEATIQYSDNAAANLLMKQIGGP -AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLNKLVLGDALGAAQRK -QLKDWMLGNTTGDTRIRAGVPAGWQVADKTGTGDYGTTNDIGVIWQPGKAPIVLVVYLTQ -PGKDDKARSEILAEASKIVVEAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D89A2 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRT -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0013E03BC8 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFYSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPLAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. BJB412 TaxID=1871178 RepID=UPI000C1039BF ---TAEARLAALESGWGGRLGVFAIDTANERGI-GFRAGERFAFCSTFKVMLATAVLERSK -QAPELLQQRIKYAKSELVNYSPITEDHVDDGMSVAELCAAAIQYSDNTAANLLIKLLGGT -AAVTAYARAIGDQEFRLDRWETELNTAIPGDPRDTTTPAAMGRSLRRLAVGDALPAPLRA -QLQDWMRGNTTGDARIRAGVPAGWQVGDKTGTGDYASANDIGVVWPPQRAPIVLAVYTAQ -ADKDAKANSEVIAAATRIVLEH- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F5832FE ----AAQMLAELERSVGGRLGVCASDIATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE6543 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLKWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE1133 -----ASSLAELERTAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119LN97_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D3A17 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754EF12 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758E6C9 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=A0A3G3HBY0_BURL3 ----AAATFARLEHDAGGRLGVCAIDTASGRRL-VHRADERFPFCSTFKAMLSAAVLAQSI -KRPALLQQRVTYTKADLVKYSPVSEKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDRAFRLDRWETELNTALPGDQRDTTTPAAMAASMRALMVGDALPAAQRA -QLVTWMRGNKVGGKRIRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIVLVVYYTQ -ASADASAKDDVIAGVASVVATAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI001326A505 -----ATSFEALERAAGGRLGVCAIDTGTGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMKLLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRVLALGDALPAPQRA -QFVTWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVTLAVYYTQ -AHADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752F28D -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759B14E -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E70B9 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSMB617WGS TaxID=1637831 RepID=A0A1B4SHA2_9BURK ---AAERQLRELESTFDGRLGFVALDTATGTRI-AYRADERFPFCSTFKTMLSAAILARSA -GDAELLQRRVRYTKRDLVNYSPITEKHVGKGMTIAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGAAQRA -QLDAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVFVVYTTM -REKNAQARSDVIASAARIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9012 TaxID=2184562 RepID=A0A3N8E6L5_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRHA-RHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDMTTPDAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIALATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E33F5 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAATTRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8963 TaxID=2184547 RepID=A0A3N8LA60_9BURK -------SLASLERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKALLSAAVLAQSV -ERPALLQQRVAYRQADLVRYSPVTERHVGAGMTVAELCAAAVQYSDNSAANLLLKLIGGP -AALTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMSASLRVLALGDALPASQRA -QLADWLRGNRTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDAGVLWPPARGPVVLTVYYTQ -AQADAKAKDDVIASATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007566D6D -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAATTRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0013F4F6E8 ----LTQRFAELEKQLDARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYTADDLVTYSPVTERHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDHHTRLDRWETELNEASPGDPRDTTTPAAMAANLQRLVLGDSLSAASRE -QLVAWMLASQTGAAKLRAGLPPGWRIGDKTGPGERGTTNEVAVIWPPQRKPVIACVYLTQ -TQASADARNAALAAIGRALAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007581EA7 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F56903F ------QMLAELERSAGGRLGVCAIDVATGRRA-EHRAEERFPFCSTFKAMLSAAVLAQSV -DRPALLQKRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVTWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -TRADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FFFA89 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia puraquae TaxID=1904757 RepID=A0A1X1PKW2_9BURK ---AAEAALADLERDAGGRLGVCAIDTARGRIV-EHRSSERFPFCSTFKAMLSAAVLAQSV -DRPGLLQQHVTYTQADLVNYSPVSGKHVGTGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGEALPAAQRA -QLVSWLRGNKVGDKRIRAGVPAGWKVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -MQADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751CE3E -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A107KA39_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0002EB9F67 -----ATSLAELERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALLTQRVTYRQADLPEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDNTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTRWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A105YNW7_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRHADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5A5172 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKTMLSAAVLAQSV -ERPGLLQQRVKYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -RLVAWLRGNKVGDKRIRAGVPAEWTVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia oklahomensis TaxID=342113 RepID=UPI00016A3D03 ---AAERQLSELESSFGGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAILARSA -GDATLLQRRIPYAKRDLVSYSPVTEKHVGDGMTVAELCAAALQYSDNTAANLLIALLGGP -QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASLRRLLVGDALGAAQRA -QLDTWMLGNTTGAARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM -RDKNAQARNDVLASAARIAARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000758DA73 -----ATSFAALERAAGGRLGVCAIDTASGRQA-RHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTIAQSDLVSYSPVSGKHVGVGMTVAELCEAEIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIASAARIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075C4B5D ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKYVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9143 TaxID=2184574 RepID=A0A3N7ZYD0_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTVAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPRSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007598E4B -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGNALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia catarinensis TaxID=1108140 RepID=A0A1J9PAI1_9BURK -----------SERDAGGRLGVCAIDTASGRSV-EHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQRRVTYGKADLVNYSPVTEKHVGAGMTVAGLCEATIQYSDNSAANLLIKLIGGP -PAVTAYARSIGDDRFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGEALPAAQRA -QLVTWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGIVWPPSRAPIVLVVYYTQ -AQADARAKDDVIASAARIAVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000752D2B3 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRLETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARIVVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E3F05 -----ASSLAELERATGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADVKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0188ED ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPHAQRA -QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075220F3 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEQHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAATTRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium macuxiense TaxID=1755647 RepID=UPI0011BFA7EA --qRLQQEFARIELATTGRLGVAALDMETGLRA-SQRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAITLSDNTAANLLLREIGGP -AGLTSFFRSVGDNVSRLDRWEVELNEAMPGDPRDTTSPVAMLKDLQRVVLGDALQANSRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVAVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753B635 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRAEERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D37C8 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B32CA -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAVATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000B7A629B ------QMLAELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVEDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPIALAVYYTQ -ARADARAKDDVIASAARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0089C8 ------ASFAALERAAGGRLGVCAIDTATGRRA-LYRAGERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDSTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPEAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8998 TaxID=2184557 RepID=A0A3N8GT26_9BURK ------TSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTVAQSDLVNYSPVSGKHVGTGMTVGELCEAAIQYSDNSAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPRSRAPIVLVVYYTQ -ARADAKAKDDVIAATARIAVAMf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755B4E6 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDRRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARANAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium macuxiense TaxID=1755647 RepID=A0A560M4X3_9BRAD --qRLQQEFARIELATTGRLGVAALDMETGLRA-SQRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAITLSDNTAANLLLREIGGP -AGLTSFFRSVGDNVSRLDRWEVELNEAMPGDPRDTTSPVAMLKDLQRVVLGDALQANSRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVAVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSh2 TaxID=1506588 RepID=A0A084DC39_9BURK ----AAQLLADLERDAGGRLGVCAIDVASGRQA-AYRADERFPFCSTFKTLLSGAVLAQSV -ERPALLQQRVTYGKADLVNYSPVTEQHVGTGMTVAALCEAALQHSDNSAANLLMKLLGGP -SAVTAYARSIGDDVFRLDRWETELNTALPGDLRDTTTPAAMVASVRALMLGDALPAAQRA -QLVAWMRGNQVGGKRFRAGVPAGWTVADKTGTGDYGTTNDVGVVWSPSRAPVVLVVYYTQ -AGADARPKEDVIASAARIVIQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B34D7 -----ASSLAELERAAGGRLGVHVLDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKRVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E9D4F -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADVKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007578982 -----ATSLAELERAAGGRLGVHALDTVTGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A071MA41_9BURK ----AAAALADLERDAGGRLGVCAIDTASGRVI-AHRPDERFPFCSTFKAMLSAVVLAQSV -DRPGWLQQRVTYTKADLVNYSPVSGKHVGSGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPAEQRA -QLVAWLRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARAKDGVIASVAQIVARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00057F6F42 ------ASFAALERAAGGRLGVCAIDAATGRRA-LHRADERFPFCSTFKAMLAAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERYVDTGMAVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATQIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A658CYX0_9BURK ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVHYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075F9860 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFAA24 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLRQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -RLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007593895 ------ASFAALERAAGGRLGVCAIDTATSRRA-LHRGDERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPPAQRA -QLIEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI0014202DD9 ----TYDALAALERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVMYTKADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPVALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000B7A1838 -----GQTLVELERSAGGRLGVCAIDIATGRRA-EHRADERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARTIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVGDKTGTGDYGTTNDAGVVWTPSGAPIALAVYYTQ -ARADARAKDDVIASAARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=Q399I5_BURL3 ------DALAVLERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTKADLVNYSPVSGKHVDDGMTVAALCEAAIQYSDNSAANLLIKLLGGP -SAVTAYARSIGDDTFRLDRWETELNDAVPGDPRDTTTPAAMAASLNALMLGGALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIALIVYYTQ -ASADARAKEDVIASVARIVVQ-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751B685 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAVATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU17325 TaxID=2015348 RepID=A0A228IJ53_9BURK -----FEALAALERDAGGRLGVCAIDTASGRRA-EHRVNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYAKADLVNYSPVTEKHVDAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVTWMRGNKVGDKRIRAGVPAGWKVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -ARADAKSKDDVIAGVARIVAKAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000752B56B ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADARAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007567C8D ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase OXY-1 n=1 Tax=Enterobacterales bacterium 8AC TaxID=2653184 RepID=A0A654BMP5_9GAMM --qQAQQQLAALEKASGGRLGVVAINTADGTTL-QLNGGQRFPFCSTFKVIAASAILHHSL -NNNGLMQQRIRYQKSDLVAYSPITEKHLDGGMTVAELCAAALQYSDNTAVNLLMKQLGGP -EAITAYARSIGDSTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPQAQRE -QLVAWMKGNTTGGKRIRAGVPAGAIVADKTGGGDYGTTNDIGIVWRENRAPLAIVVYFTQ -PQQDAKANNEVIAAAARIVNQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C9757 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASVRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A1R1J976_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARPDAKRKDDVIAAATRIAI--- ->[subseq from] Class A beta-lactamase n=1 Tax=Serratia oryzae TaxID=2034155 RepID=A0A1S8CQC7_9GAMM --qQAQQQLAALEKASGGRLGVVAINTADGTTL-QLNGGQRFPFCSTFKVIAASAILHHSL -NNNGFMQQRIRYQKSDLVAYSPITEKHLDGGMTVAELCAAALQYSDNTAVNLLMKQLGGP -AAITAYARSIGDSTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPQAQRE -QLVAWMKGNTTGGKRIRAGVPAGAIVADKTGGGDYGTTNDIGIVWRENRAPLAIVVYFTQ -PQQDAKANNEVIAAAARIVSQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0009820474 ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAASLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000982228D ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWGTELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757E2D7 -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAVSLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0004D73547 -----FEALAALERDAGGRLGVCAIDTASGRRA-EHRVNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYAKADLVNYSPVTEKHVDAGMTVAALCEAAIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASMRELMVGETLPAAQRA -QLVTWMRGNKVGDKRIRAGVPAGWKVGDKTGTGDYGTTNDAGVIWPTSGAPIVLVVYYTQ -ARADAKSKDDVIAGVARIVAKAf ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8695 TaxID=2609281 RepID=UPI001420611B ---DAHASLAALEKAAGGRLGVAALDTGTGRQL-GHRASERFPMCSTFKAIAAAAILAHAS -KVPGLLAQRVRYTRADLVTYSPITEQELDKGMTVAELCEATIQYSDNAAANLLMKLIGGP -AGVTAFARSVGDATFRLDRWETELNTAIPGDPRDTTTPQAMTTLLRRVALDDGLPPAQRD -QLQEWMRGNTTGAARIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ -AAPDAKANSEILAAATRIVMEHf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007563B86 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119HGA0_9BURK -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000DACA787 ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPLCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVHYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000841CDF8 ------DALAELERSAGGRLGVCAIDIASGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQKRVRYTKADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVMWSPSGAPVALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia thailandensis TaxID=57975 RepID=A0A659JMJ0_BURTH ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALDTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) TaxID=271848 RepID=UPI00098014B6 ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007583351 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520G0T8_9BURK ---ALSTQLAAIEKASGGRLGVGILDTAAGHSA-GHRQDERFPLCSTFKFLAGAAVLARVD -QRKERLDRRVTFERRDLVTYSPVTEKHVGPGITVAELCDAAITLSDNTAGNLLLASLGGP -QGLTAFMRSIGDTHTRLDRTEPTLNEARAGDPRDTTTPGAMARSMQKILLGDALTPASRA -QLLQWLDANKTGGERIRAGLPADWKVGDKTGSGANGATNDVAILRPPARAPILLAIYLTE -TQASAPARNKTLASVAQAVA--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756D903 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVSEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000754B8D7 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075472C9 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754E976 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B82C7 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADATRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753168B -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. HMSC10F09 TaxID=1581083 RepID=UPI0008A1EBFE ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDSTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDVGVMWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE6CC7 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAIMIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075823A2 ------TSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B6B85 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. RF2-non_BP3 TaxID=1637844 RepID=A0A102EVG8_9BURK -----ATSFAALERAAGGRLGVCAIDTASGLHA-LHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -EAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPVQRA -RLIAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BB1B1 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKRVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWEVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000759D102 ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTFTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPGGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARAKDDVIASVARILVQAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A108IZ65_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADATRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Serratia sp. Ag1 TaxID=1524467 RepID=A0A087L3C7_9GAMM --qQAQQQLAALEKASGGRLGVVALNTADGQML-QLNAEQRFPFCSTFKVIAASAILHHSL -SHGGFMQQRIRYQQSDLVTYSPITEQHLDSGMTIAELCAAALQYSDNTAVNLLMKQLGGP -AAITAYARSIGDTTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPKAQRE -QLVAWMKANTTGDKRIRAGVPAGARVADKTGGGDYGTTNDIGIVWQANRAPLVIVVYFTQ -PQQDAKAKNEVIASAAQIVSQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759C902 -----ATSLAELERAAGGRLGVHAFDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLDWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARVDAKRKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. BR0G17 TaxID=2269368 RepID=UPI0013DF26C6 ---ALADTCTRLEAGSGGRLGVGLLDTAGGRMI-GHRLDERFPMCSTFKALAAGVVLARVD -RKQENLDRRVNYTKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP -AGLTSFARSLGDETTRLDRIETELNQALPGDPRDTTSPRAMAQTLRALTLGDALSATSRA -QLIAWLKANTTGGTRLRAGVPSGWAVADKTGTGDHGTANDVAVLWPPQRAPLIVTVYLTG -AAVARDQQNKIIADIGAAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis TaxID=57975 RepID=A0A2N8R726_BURTH ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia thailandensis TaxID=57975 RepID=UPI00016A8E6C ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756F314 -----ATSLAELERAAGGRLGVHALDIATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756C6EB -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAVATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. GV090 TaxID=2135673 RepID=A0A4R2WHV7_9BURK ------SAFAALEKDLGGRLGISAVNLATGKQV-GHRSGERFPMCSTFKAMVAAAILQRSA -SDPALLKRRISYTKADLVPHAPVTEKHIDQGMTVEELCAAMVQYSDNPAANLLMKVLGGP -EAVTAFARSIGDTDFRLDRWETELNSAIPGDPRDTTTPQAMMRSLQALVMGDALPAPQRQ -QLKDWLVGNTTGAKLIRAGVPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH -EKADAKYREDIIAGATSTA---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. 2002721687 TaxID=1468409 RepID=A0A0D5L6X1_9BURK ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKMMLSAAVLARSA -DDAALLQRRIPYAKRDLVRYSPITERHVGAGMTVAELCAATLQYSDNTAANLLIDLLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLAGDALGAAQRA -QLNAWMLGNKTGDARLRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSQNAPVRDDVIAAAARIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000980EB5C ----AAATLADLERDAGGRLGVCAIDTASGRVI-EHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYTKADLVNYSPVSEKHVGAGMTVAALCEATIQYSDSSAANLLMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWVVGDKTGTGDYGTTNDAGVIWPTSRAPIVLAVYYTQ -TRADARAKDDVIASVARIVAQTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007569088 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE99DA -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRAEERFPFCSTFKAILIAAVLAESV -ACPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F4FE2 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -TRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAVATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFEBD6D ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVNYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKRIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLSEWLRGNKVGDKRIRAGVPTAWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -ARADAKAKDDVIAAATRIAI--- ->[subseq from] LUT family class A extended-spectrum beta-lactamase n=1 Tax=Chitinimonas sp. BJB300 TaxID=1559339 RepID=A0A2G3K1G1_9BURK ----TKARLQKLESDFGGRLGVFAVDAANGAVL-SYRADERFPFCSTFKVLAASAILNKSG -DVAGLMQQRINYSQSDLVNYSPITEKHVADGMTIAELCAAAIQYSDNTAANLLIKTLGGP -DAITAFARSIGDTKFRLDRWETALNTAIPGDPRDTSTPEAMGRSLQRLVLGDALAREQCE -QLRDWLYGNTTGAARIKASIPADWKIGDKTGTGSYGTANDIAFVWPPQRKPVVIAIYTTQ -DKEDAQARNDVIASAARILVD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A117XR52_9BURK ------TSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFAQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759A5D6 -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFMQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754C0B3 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARSALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADATRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D6C95 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRT -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVU6_9BACT ----LATKLAEIEARLGARLGVAILDTQTGRHW-EHRADERFPLCSTFKVLACGAILARAD -VGQEDLDRRIRFEASDVVTYSPVTQNRVGGEMTLAELCEAAITQSDNTAGNLILESLGGP -HSVTEFARSLGDSVTRLDRWETDLNEAKPGDPRDTTTPKAVLADLQSLILENVLSRQSRE -QLARWMVANKTGDAKLRAGLPDDWRIGDKTGGGDYGTMNDVAVIWPPDREPLIISVYMTE -SEASFDDRNAAVADIGRAV---- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D6BDB -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGL -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia paludis TaxID=1506587 RepID=UPI0004DB7204 ----AAQLLADLERDAGGRLGVCAIDVASGRQA-AYRADERFPFCSTFKTLLSGAVLAQSV -ERPALLQQRVTYGKADLVNYSPVTEQHVGTGMTVAALCEAALQHSDNSAANLLMKLLGGP -SAVTAYARSIGDDVFRLDRWETELNTALPGDLRDTTTPAAMVASVRALMLGDALPAAQRA -QLVAWMRGNQVGGKRFRAGVPAGWTVADKTGTGDYGTTNDVGVVWSPSRAPAVLVVYYTQ -AGADARPKEDVIASAARIVIQAf ->[subseq from] class A beta-lactamase n=1 Tax=Xenophilus azovorans TaxID=151755 RepID=UPI000A8CD459 ----ARERLAAIESGFDGRLGVFAIDTADGATL-AHRGDERFPLCSTFKLVAAAALLARST -AEPRLMSERVHYTRAELASWSPVAEKHVARGMTYEELCAAAVMYSDNTAANLMLRRLGGP -AALTDYARGLGDAAFRLDRWEPELNTAIPGDPRDTTTPAAMARTVRRLVLDDALPAPQRA -QLEAWLRGNTTGATRIRAGVPSTWAVGDKTGAGDYGTNNDVGVLWPPGRAPIVLAVYTTQ -RQPDAKARNDVIAEAARAVAQ-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756320B -----ASSLAELERAAGGRLGVHALDTATGRRV-LHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAVATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI0011F00B60 --kRLADAIAALETRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRRIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPTVGDP -AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGTRGTANDVGIVWPEGRAPLLIASYLTE -TADAFKERDAIHAGVARAVAD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE0756 -----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia thailandensis TaxID=57975 RepID=Q2T5A3_BURTA ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EB3E0 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPRARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BED4D -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAVVLAESV -ARPALFTRRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia complex TaxID=87882 RepID=UPI00075BEAE2 -----ATSFAALERAAGGRLGVCAIDTASGLHA-LHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -EAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPVQRA -RLIAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751AFE6 -----ASSLAELERAAGGRLGVHVLDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVTAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075FC8A7 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPVLLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007594016 ------TSLAEFERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A6B9AWB4_PSEST --eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYTADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD -QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ -TQASAEERNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A1B4LN50_9BURK -----AATFAALERAAGGRLGVYALDTATGRRV-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYVQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKGRDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007550135 ------TSLAELERAEGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000CF0C82C ------QMLAELESSVGGRLGVCAIDAASGRVI-AHRADERFPFCSTFKAMLSAAVLAQSV -ERPALLQQRVTYTRADLVNYSPVSEKHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPCDLRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSRAPIAVAVYYTQ -ARADARSKDDVIASVARILVQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000760B681 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADGRFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754A0BC ------TSLAELERAAGGRLGVHALDTATGWRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDRGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007551C3E -----ATSLAELERAAGGRLGVHALDTVTGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075415F6 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000755708C ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPSAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F5620A2 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADARAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB0856 TaxID=1637869 RepID=UPI00075B6F39 -----ATSFAALERAAGGRLGVCAIDTASGLHA-LHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTIAQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -EAVTAYARSIGDDMFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRVGVPAGWQVADKTGTGDYGTTNDAGVIWPPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075DAB9C ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYHQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Serratia oryzae TaxID=2034155 RepID=UPI0012E2BD6C --qQAQQQLAALEKASGGRLGVVAINTADGTTL-QLNGGQRFPFCSTFKVIAASAILHHSL -NNNGFMQQRIRYQKSDLVAYSPITEKHLDSGMTVAELCAAALQYSDNTAVNLLMKQLGGP -EAITAYARSIGDSTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGNALPQAQRE -QLVAWMKGNTTGGKRIRAGVPAGAIVADKTGGGDYGTTNDIGIVWRENRAPLAIVVYFTQ -PRQDAKANNEVIAAAARIVNQAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075721B3 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRVDERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757D4A6 -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRLEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDVGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075ABDC5 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHCADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752FA4B -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRLEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1B4Q267_BURCE -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAMLSAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -SAVTAFARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMLGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAI--- ->[subseq from] UPI00132CDA17 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00132CDA17 ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAADLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] class A beta-lactamase n=1 Tax=Rugamonas rubra TaxID=758825 RepID=UPI000B879395 ---TAEARLAALESGWGGRLGVFAIDTANERSI-GFRAGERFAFCSTFKVMLAAAVLERSK -QVPDLLQQRIKYAKSELVNYSPITEDHVEDGMSVAELCAAGIQYSDNTAANLLIKLLGGT -AAVTAYARAIGDQEFRLDRWETELNTAIPGDPRDTTTPAAMGRSLRRLAVGEALPAPLRA -QLQDWMRGNTTGDARIRAGVPAGWQVGDKTGTGDYASANDIGVVWPPQRAPIVLAVYTAQ -ADKDAKANSEVIAAATRIVLEH- ->[subseq from] Beta-lactamase n=6 Tax=Klebsiella TaxID=570 RepID=Q5PXN8_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAARIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075949B1 ------TSLAELERAEGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFAQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Rugamonas rubra TaxID=758825 RepID=A0A1I4SPD7_9GAMM ---TAEARLAALESGWGGRLGVFAIDTANERSI-GFRAGERFAFCSTFKVMLAAAVLERSK -QVPDLLQQRIKYAKSELVNYSPITEDHVEDGMSVAELCAAGIQYSDNTAANLLIKLLGGT -AAVTAYARAIGDQEFRLDRWETELNTAIPGDPRDTTTPAAMGRSLRRLAVGEALPAPLRA -QLQDWMRGNTTGDARIRAGVPAGWQVGDKTGTGDYASANDIGVVWPPQRAPIVLAVYTAQ -ADKDAKANSEVIAAATRIVLEH- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EA2BD -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRLEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDVGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Nafp2/4-1b TaxID=2116686 RepID=A0A495YSC9_9BURK -----AKSFASLERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV -EHPGLLQQRVTYGQADLVNYSPVSSKHVGTGMTVAELCEAAIQYSDNAAANLAMKLLGGP -AAVTAYARTIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -TRADAKAKDDVIAAAARIAVATf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium viridifuturi TaxID=1654716 RepID=UPI00067EDDC8 --qRLQEEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVMLGDVLQAASRQ -KLVDWMVANKTGDTRLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A118HZB6_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARPDAKRKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium sp. a22-2 TaxID=2283840 RepID=UPI00144582A9 ----MAATLQEIERRIAARLGVAILDMETGRQW-SHRGDERFPMCSTFKAIASAAVLARVD -AGQEDLERRIKISADDIIAHAPAAEKRIGGFMTMGELCAAAVTLSDNTAANLILKSLGGP -EGFTRFLRSIGDKTTRLDRWEPELNEAKPGDPRDTTTPAAMAKTLQTLVTGDALTPQSRQ -QLSAWMIANTTGAGKLRAGLPRDWVVGDKTGSGRLGTANDIAVLWPPERKPIFVAVYITE -TKATMDDRNAAMAEIARTMV--- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ04_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A4P9DY74_PSEST --eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD -QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ -TQASAEERNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A8DS72_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=A0A1B4P284_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVMYGQADLVNYSPVSGKHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRALVLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPPGSQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -AQPEAKAQEDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. DFCI-1 TaxID=1230476 RepID=U1I9A1_9BRAD --qRLQEEFARIELATSGRLGVAALDMETGLRA-NRRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAITLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVVLGDVLQAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A345IT65_9BURK ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADARAKDDVIAAATRIAV--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9126 TaxID=2184570 RepID=A0A3N8BD33_9BURK ----AATSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPSCSTFKAMLIAAVLAQSV -TRPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMKLLGGP -AAVTAFARAIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVTLAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000D1A767A ---ALADTCARLEAGSSGRLGVGVLDTASGRMI-GHRLDERFPMCSTFKALAAGLVLARVD -RRQDNLDRRVNYTKSDLVTYSPATEKHVEGGMTIAELCEAAVTLSDNTAGNLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQTLRALTLADALSATSRA -QLIAWLKANTTGGTRLRAGVPSGWVVADKTGTGDHGTANDVAVLWPPQRAPLIVTVYLTG -AAVARDQQNKIIADVGAAVAD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D005AB9 ------ASFAALERAAGGRLGVCAIDTATGRRT-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDSTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPTGWRVGDKTGTGDYGTTNDAGVLWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F1C23 -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMTASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007526A06 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGVALPAPQRA -QFAQWLLGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. SRS-46 TaxID=2094191 RepID=A0A4R4CHE4_9BURK ------TSLEALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLTQSV -ARPALLAQRLMVRQADMVGYSPVTEKHVGTEMTVGELCEATAQYSDNAAANLLMKLLGGP -SAVTAFMRTIGDDTFRLDRWETDLNTALPGDPRDTTTPAAMAASLRVLALGDALPAPQRA -QFTAWLRGNKTGDRRIRAGVPAGWQVGEKTGTGDYGTTNDIGVLWPPARGPIALAVYYTQ -ASPDAKAKDGVIAAAARIVIA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757EE52 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGL -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Massilia TaxID=2609279 RepID=UPI000D3197BC ------SAFAALEKDLGGRLGISAVNLATGKQV-GHRSGERFPMCSTFKAMVAAAILQRSA -SDPALLKRRISYTKADLVPHAPVTERHIDQGMTVEELCAAMVQYSDNPAANLLMKVLGGP -EAVTAFARSIGDTDFRLDRWETELNSAIPGDPRDTTTPHAMMRSLQALVVGDALPAPQRQ -QLKDWLVGNTTGAKLIRAGVPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH -EQADAKYREDIIAGATSTA---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A118Q2C0_BURPY ------TSFDALERAAGGRLGVCAIDTATGRRV-QYRADERFPFCSTFKAMLIAAVLAQSV -TRPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGGALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A107APN2_9BURK ------TSFDALEHAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium sp. LTSP885 TaxID=1619232 RepID=A0A0D7NQZ6_9BRAD --qRLQQEFARIELATSGRLGVAALDTETGLRA-SLRGDERFPMCSTFKALATAAVLHRVD -RGESSLDQRVQIQAKDILAYAPITKEHVGSDMTLSELCEAAITQSDNTAANLLLRELGGP -AGLTNFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPAAMLKNLQRVVLGDVLQATSRQ -KLADWMVANKTGDARLRAGVPRDWRVGDKTGTGDRGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPAAKCDEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Afipia sp. 1NLS2 TaxID=666684 RepID=D6VB26_9BRAD --qDLKSKISRIESRVKGRLGVAVLDTGSDRRF-GYRKDERFPMCSTFKLMAAAAILKRVE -QGQETLERRVHFSQSDLVTYSPATEKHLESGMTVAELCEAAITLSDNTAGNLMLGMLGGP -PGVTAFARALGDPLTRLDRTELALNEAVPGDPRDTTTPAAMAEDLRKLMFGGALAKASSE -QLKAWLLANKTGDARLRARLPAGWRVGDKTGSGERGSTNDVGILWPPDAAPLIAAVYLTQ -TAASMNERNEALAAVGEAVAAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759011D -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAVLIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPVPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADATRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. DCY119 TaxID=2108445 RepID=A0A3A3I1R5_9RHIZ ---DAAAQLRALEKKYGGRLGVAILDTASGTRI-EHRADERFALCSTFKVLASAAVLARVD -KGEEKLDRRITYEKKDLVTYSPVTEKHVGKKMALAELCEAAITLSDNTAGNLLLASFGGP -AGLTAYARTLGDEVTRLDRIETALNEAKTGDPRDTTTPAAMLADLQKLVLGDGLSPASRD -QLKTWLLANKTGDKRLRAYLPKDWKVGDKTGTGDNGSANDVGILWPPKHGPIIVSSYFTE -SSASTDEKNIVHAEVGRIAA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1S7BHJ3_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D4L6Q1_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -EGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. BDU8 TaxID=1385592 RepID=A0A1B4FTV3_9BURK ----AERQLGELESSFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAILARSA -GDATLLRRRIPYAKRDLVSYSPITEKHVGEGMTVAELCAAMLQYSDNTAANLLIALLGGP -QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGAAQRA -QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM -RDKNAQARDDVLASAARIAARTf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757778F -----ATSLAELERAAGGRLGVHALDTVTGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADATRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobiaceae TaxID=41294 RepID=A0A336JT72_9BRAD --eQFAAKLADLEAGSGGRLGVGVLDTANGRMT-GHRLDERFPMCSTFKALAAGLVLARVD -RGQESLDRRVRYAASDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAGNLLLASFGGP -VGLTAFARSLGDETTRLDRIETELNEALPGDPRDTTSPRAMAQDLRALTLGDALSATSRA -QLIAWLKANTTGGTRLRAGVPAGWAVGDKTGTGDHATANDVAVLWPPQRPPLIVTVYLTG -ATVARDQQNKIIAAVGAEVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=H6V561_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007544704 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPVPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADATRKDDVIAAATRIAI--- ->[subseq from] class A extended-spectrum beta-lactamase CTX-M-140 n=1 Tax=Proteus mirabilis TaxID=584 RepID=UPI0007A58C76 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075B825B ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F7EA1 -----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDRRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVTAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000988A2CF --eDLTHRFAALEKQLEARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD -QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ -TQASAEERNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Chania multitudinisentens RB-25 TaxID=1441930 RepID=W0LJ18_9GAMM ----AQQQLAALEKASGGRLGVVVIDTAGGETL-QLNGEQRFPFCSTFKMMVAGAILHHSV -SNPGFMQQPVRYSKSDLVAHSPVTEKHLNRGMSVAELCAATIQYSDNAAANLLMKQLGGP -AAITAFARSIGDTAFRLDRWETELNSAIPGDERDTTTPAAMASSLQKLALGNALPEAQRE -QLVIWMKGNTTGDQRIRAGVPAGAIVADKTGGGSYGTTNDIGIVWQEKRAPLVIAIYFTQ -PQQDAKANNEVIASATRIASQAf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0006B990F5 --eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD -QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ -TRASAEERNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DPN4_9PSEU -----TDRLAELERRFDARLGVYALDTGSGREV-AHRADERFAMCSTFKALAAAAVLDATP ---PEHLDQRVHYAQADLVDYSPVTEQHVADGMTIRELCDAAVRFSDNTAGNLLLADLGGP -GGITALARSLGDDVTRLDRIEPELNTAIPGDERDTTSPRAMAGCLDALVLGDRLGPDDRA -LLTGWLVGNTTGDARIRAGVPDGWRVGDKTGTGSYGTTNDVGVVWPPDRAPIVLVLLSSR -TTEDADNEDALLAEATRVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=H6V562_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARSIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI0008418112 ---DAQRALRELEASFDGRIGVAALDTATNAKI-AYRADERFAFCSTFKMMLSAAVLARSA -AEPDLLPRRIVYAKRDLVEYSPITGKHAGAGMTTAELCAAALQYSDNTAANLLISLLGGP -QAVTAYARSIGDAEFRLDRRETELNTAIPGDLRDTTTPSAMAASLRRLLLGDALGQAQRE -QLNAWMLGNTTGNERIRAGVPPAWRVADKTGTGDYGTANDIGVLYPPGRAPIVLAIYTTG -RAQQARARNDVIASAARIVARAf ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A2T2Y7V0_9ENTR ---AVQQKLAALEKSSGGRLGVALIDTEDNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFAREIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium mercantei TaxID=1904807 RepID=UPI000B5ADCA9 --qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVMLGDVLQAASRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDVGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVS--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841C062 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNYSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGNYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BHI2_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARSIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008420CD1 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFWLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. HMP271 TaxID=1487922 RepID=A0A099RVB7_9PSED --eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYTTDDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRD -QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ -TQASAEDRNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. TSV86 TaxID=1385594 RepID=A0A103ED48_9BURK ---DAQRSLRELEASFDGRIGVAALDTATNAKI-AHRADERFAFCSTFKMMLSAAVLARSA -AEPDLLPRRIAYAKRDLVEYSPITGKHVGAGMTAAELCAAALQYSDNTAANLLISLLGGP -QAVTAYARSIGDAVFRLDRWETELNTAIPGDLRDTTTPSAMAASLHRLLLGDALGQVQRE -QLNGWMLDNTTGNERIRAGVPTAWRVADKTGTGDYGTANDIGVLYPPGRAPIVLAIYTTG -RVQQARARNDVIASAARIVARAf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium mercantei TaxID=1904807 RepID=UPI0009786C1C --qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVMLGDVLQAASRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDVGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVS--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075F7D2B ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ -ARADARAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Variovorax TaxID=663243 RepID=A0A109BSD1_9BURK ---DLARQFAEIEKKTGGRLGVHVLDTATARRA-GHRQDERFAMCSTFKFLAAALVLARVD -QGKERLERRITYARDELVTYSPVTEKHAGTDMSMAQLCEAAVTLSDNTAANLMLASVGGP -AGLTAFMRSLGDPHTRLDRIEPGLNEARAGDPRDTTTPAAMVDSMQKILLGDALSPGSRA -LLLQWLDDNKTGGERIRAGLPADWKVGDKTGTGENGAANDIAILRPPGRPPVLLSVYLTE -TKASMADRNAAHAAVAAAVV--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075C799B -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKTMLGAAVLARSV -EHPGLLQQRVTYAQADLVNYSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTSYARSIGDDTFRLDRWETALNTALPGDPRDTTTPAAMAASIRALTLGDALPAPQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D009FAF ------ASFAALERAAGGRLGVCAIDTATGRRA-LHRADERFPFCSTFKAMLGAAVLAQSV -AHPGLLQQRVTYGRSDLVSYSPVTERHVDTGMTVAELCAATIQYSDNTAANELMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLVLGDALPAAQRA -QLIEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVMWPPSRAPIVLAVYYTQ -TRADAKAKDDVIATATRIAI--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C6EC0 -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMMVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=W0T351_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Caballeronia choica TaxID=326476 RepID=A0A158KK39_9BURK ----SASRLKALEDASNGRLGVAAFNTADGAQL-SYRADERFPFCSTFKLLLTSAILARSA -HDDGLLARRITYAQGDLVNYSPVSEKHVADGMTVAELCAAALQYSDNSAANLLIRLLGGP -SAVTAFARSIGDHEFRLDRMETELNTAIPGDLRDTTTPAAMARDLQRLALGDALGTAQRD -QLQTWMRGNTTGDARVRAGVPRDWQVADKTGTGDYGTSNDIAVLWPPAKPPIVVVIYFTQ -REPDAKARNDVIASAAKIIAGRf ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium zhangyense TaxID=1776730 RepID=UPI0013EC91E8 ---DAAAQLRALEKKYGGRLGVAILDTANGTRI-EHRADERFALCSTFKVLASAAVLARVD -KGEEKLDRRITYEKKDLVTYSPETEKHAGKKMTLAELCEAAITLSDNTAGNLLLASFGGP -AGLTAYARTLGDEVTRLDRIETALNEAKTGDPRDTTSPAAMLADLQKLVLGDALSPASRD -QLKTWLLANKTGDKRLRAHLPKDWKVGDKTGTGDNGSANDVGILWPPKRGPIIVSSYFAE -SSASTDEKNTVHAEVGRIAA--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007564A1D -----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -SRPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDRRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVTAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. R5(2019) TaxID=2697566 RepID=UPI001411F7E2 -------RCAALEKQLNGRLGVFALDTGNDTQL-GYRATERFAVCSTFKMMLAAAVLKFSE -RKPGVLQQRLRYSKSELVSYSPVTERYIDEGMTVAELCAAAVQYSDNTAANLLIKLLGGP -SAVTEFARSIGDQAFRLDRWETELNTAIPGDPRDTSTPAAMGRSLQRLVLGNALEPAQAA -QLQAWLRGNTTGDERIRAGVPSGWQVGDKTGTGDYASASDIGVVWPPQRAPIVVAIYTTQ -PEKDAKPRNDIIAEAARVVAD-- ->[subseq from] Beta-lactamase n=10 Tax=Bacteria TaxID=2 RepID=Q9L5C6_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTKDNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFAREIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=A0A2R4GPD3_RHOPL ---ALADRCARLEAGSGGRLGVGVLDTAGGSMI-GHRLDERFPMCSTFKALAAGLVLARVD -RKQESLDRRVSYAKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP -AGLTAFARSLGDDTTRLDRIETELSQALPGDPRDTTSPRAMAQTLRALTLGDALSATSRA -QLIAWLKANTTGGTRLRAGVPSGWVVADKTGTGDNGTANDVAVFWPPQRAPLLVTVYLTG -ATVARDQQNKIIADVGVAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A560BJX7_AZOBR --kRLADAIAALEKRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGSERLDRRIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMAQSMERLMLGDALTAASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TPDSFKERDATHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSHR3999 TaxID=1542965 RepID=A0A0D0FMP9_9BURK -----ASSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAVVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSISDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Andreprevotia chitinilytica TaxID=396808 RepID=UPI000556022C ---SMQARFAKLEADLNGRLGVFAVNTANGAQL-QYRADERFAFCSTFKMMLASAILARSA -QVDGLLQQRIPYAQGDLVSYSPITEKHVGEGMAVADLCAAAVQYSDNTAANLLIKLLGGP -AAVTAFARSIGDRVFRLDRWETALNTAIPGDPRDTTTPKAMGLSLQRLALGDALTPPLAT -QLQDWLRGNTTGAARIRAGVPADWQVGDKTGTGDYGSANDIGVVWPPQGAPIVIAIYTTL -REKDGKARNDVIAAAARVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. IDO3 TaxID=1705310 RepID=A0A2A4CHA6_9BURK -----TTTFAALERAAGGRLGVCAIDTASGRRA-QHRADARFPFCSTFKTMLSAAVLAQSV -ERPGLLQQRVMIGQGDLVNYSPVSSKHVGTGMTVAALCEAAIQYSDNSAANLLMKMIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASLRVLTLGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVMWPPSGAPVVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000536CB97 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0006222E5C -----AATFAALERAAGGRLGVCAIDTASGWRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. PBL-H6 TaxID=434009 RepID=UPI0013A58E12 ---ALARQFAEIEKKTGGRLGVHVLDTANGRRA-GHRQDERFAMCSTFKFVAAALVLARVD -RGQERLDRRVAYSRNDLVTYSPVTEKHAGTDMTMAQLCEAAVTLSDNTAGNLMLASFGGP -AGLTAFMRSLGDAHTRLDRIETALNEARAGDPRDTTTPAAMVGSMQKILLGDALSPASRT -QLLQWLDGNKTGGERIGAGLPADWKVGDKTGTGENGAANDIAILRPPGRAPILLSVYLTE -TKASMADRNAAHAAVAAAVV--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007574EB7 -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKRVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMVASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] UPI00065004F1 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00065004F1 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas yeongjuensis TaxID=377616 RepID=UPI001390BD6C -------QLEALEHRYGGRLGVSILDTGSGKRI-GHRADERFPMCSTFKFLAAAQVLTRVD -RGEEKLERRIVFAKKDLVAYSPMTEKHAGAPMTLAELCHAAITLSDNTAGNLLLDSFGGP -AGLTAFARTLGDTVTRLDRRETELNEAIPGDPRDTTTPAAMLDDMRRLLLGDALSPASRK -QLADWLLANTTGAARLRAGLPGDWRVGDKTGTGANGASNDIAIVWPPDRAPLLVTAYYAE -SSIPQETRNAVLVEVGRIAA--- ->[subseq from] Beta-lactamase Toho-1 n=3 Tax=Escherichia coli TaxID=562 RepID=UPI0001B04C54 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAENRNDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A385FUV0_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAVLQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI000757CD4C -----ATSFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVMYGQADLVNYSPVSGKHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRALVLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPPGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -AQPEAKAQEDVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000756828D -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004F59A9C -----ATSFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVMYGQADLVNYSPVSGKHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP -AAVTAFARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRALVLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPPGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -AQPEAKAQEDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A3N8RBQ2_9BURK ------QMLADLERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVTYTQADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGWTVADKTGTGDYGTTNDAGVVWSPSRAPIALVVYYTQ -ASADARAKEDVVASVARIVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A2T0NYI7_RHITR --qRLQEEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSAMTLAELCEAAVTLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVELNEAMPGDPRDTTSPVAMLKDLQRVMLGDVLQAASRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=F1CLN0_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRE -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P8NAV4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDKTFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F57C891 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADALAKDDVIAAATRIAI--- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI000BA179AB ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E75C5 -----ASSLAELERTAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEVTAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRASVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKGKDDVIAAATRIAVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Capsulimonas corticalis TaxID=2219043 RepID=A0A402CT55_9BACT ---SAQAQFASLEKSLNGRLGVYALNTADGSQM-SYRADERFPLCSTFKIMLASAILHRSA -RTPELLGRRIRYTAQDLVTYSPITEKHVGDGMTIAELCAAALQYSDNTAANQLMKILGGP -AAVTAFSRLIGDRVFHLDRWETELNTAIPGDLRDTSTPRAMGRSLKRLALGDALPPHQRR -QLQEWMRGNTTGKKRIAAGVPANWLVGDKTGTGDYGSANDVAILWPPRHAPILLAIYTTQ -HEKNAKAREDVIASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9017 TaxID=2184565 RepID=A0A3P0NIN3_9BURK -----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRAGERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVMVGQGDLVNYSPMSSKHVGTGMTVAALCEAAIQYSDNSAANLLMKMIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDQRDTTTPAAMAASLRVLALGDALPAAQRA -QLVAWLRGNKVGDKRIRAGVPAGWQVADKTGTGDYGTTNDAGVMWPPSGAPVVLVVYYTQ -TRADAKAKDAVIAAAARIAVATf ->[subseq from] Beta-lactamase n=5 Tax=Klebsiella TaxID=570 RepID=Q206M3_KLEPN --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKLLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000975B6F3 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIIYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=UPI0002D93B0D ------TSFDALERAAGGRLGVCAIDTATGRRV-QYRADERFPFCSTFKAMLIAAVLAQSV -TRPALLVQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLALGGALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G4RJI0_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9125 TaxID=2184569 RepID=A0A3N8BY78_9BURK ----AATSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -TRPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMTLLGGP -AAVTAFARAIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGAPAGWQVGDKTGTGDYGTTNDVGVLWPPAREPVTLAVYYTQ -ARADAQAKDDVIAAATRIAL--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007582E69 -----ASSLAELERAAVGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKLVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8T2W7_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAEHRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1W1H4E2_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHSf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ23_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A346D4G3_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAEHRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAG1_KLEPN --nAVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=7 Tax=Enterobacterales TaxID=91347 RepID=Q4LB53_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU29985 TaxID=2153378 RepID=A0A2R7YEI3_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSI -AQPALLQQRVAYGKADLVSYSPVTEQHVGAGMTVAELCAATIQYSDNTAANVLMKLIGGP -QAVTAYARSIGDATFRLDSWETELNT-LPGDPRDTTTPAAMAASLRALMLGDALPSAQRA -QFVEWLRGNKVGDKRIRAGVPAGWRVGDKTGTGDYGTTNDAGVAWPPSGAPIVLAVYYTQ -ARADARAKDDVIAAATRIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754CE3B -----ASSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMMVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALVLGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWSPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAVA-- ->[subseq from] Beta-lactamase n=2 Tax=pseudomallei group TaxID=111527 RepID=A0A291CER7_BURTH ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKMMLSAAVLARSA -DDAALLQRRIPYAKRDLVRYSPITERHVGAGMTVAELCAATLQYSDNTAANLLIDLLGGT -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLAGDALGAAQRA -QLNAWMLGNKTGDARLRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSQNAPVRDDVIAAAARIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007581400 ------TSFDALECAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2S1PK93_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0007058CA7 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGGYGTANDIGVAYPPNRAPIVFIIYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=32 Tax=root TaxID=1 RepID=Q840M4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1Z1Z4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=D2KL97_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAENRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=A0A1A9KHQ2_9PSED ---STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD -RGEEQLARRIVYGQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -TGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQPASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPASAEKREAVLAEVGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S6KJQ0_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3G2I6P7_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=51 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9L5C7_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] UPI001019E979 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI001019E979 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=A3NJ57_BURP6 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIIYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A345IT62_9BURK -----AAALADLERNAGGRLGVCAIDTASGRSV-EHRPNERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYSKADLVNYSPVTERHVDTGMTVAAMCEAAIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDLRDTTTPAAMAASTRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGMPAGWTVGDKTGTGDYGTTNDAGVIWPASGAPIVLVVYYTQ -AQADARSKDDVIASAARIV---- ->[subseq from] LUT family class A beta-lactamase n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=A0A5P2SA86_PSELU ---SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVATGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ESQQAEARNDVLADAARIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. VT-16-41 TaxID=1953765 RepID=A0A1V2VB31_9BURK ---SIVQKLAQLEADIGGRLGVSLVDTVHGRQW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGRERLARRIVYRQQDLVPYSPTTGKHTGGALSMAQLCEAAITLSDNTAANLMLASMGGP -AGLTGFVRTLGDELTRLDRNEPTLNEAIPGDPRDTTTPAAMTADLRQVVLGNALAPASRE -QITQWLLANQTGDKRVRAGLPAGWKVGDKTGTGDRGTANDVGVVWTPQGAPLLFAVYLTE -NTAEAARRDAVHAEVGRLIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella derby TaxID=28144 RepID=B6E9R8_SALDE ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVAWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase (Fragment) n=118 Tax=Bacteria TaxID=2 RepID=A2TCA1_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104JDJ7_9BURK -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAETV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDESFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVLTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLAVYYTQ -ARADAKRKDDVIAAATRFAI--- ->[subseq from] Beta-lactamase n=17 Tax=Gammaproteobacteria TaxID=1236 RepID=C8CP57_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=R4I5F6_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRHDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A142IX48_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAKSRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Azospirillum brasilense TaxID=192 RepID=G8AUN0_AZOBR --kRLADAIASLEKRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRRIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TPDAFKERDAIHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. HH01 TaxID=1198452 RepID=L9PCN3_9BURK ------ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP ----ALLKKRVAYRKSDLVTYSPITEKHVGKGMTVAALCEATIQYSDNAAANLLMKQIGGP -AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPDAMAESLNKLLLGDALGAAQRK -QLKDWMLGNTTGDTRIRAGVPAGSVVADKTGTGDYGTTNDIGVIWQPGKAPIVLVVYLTQ -PGKDDKARSEILAEASKIVVEAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. BR0C11 TaxID=2269370 RepID=UPI0013E073C0 ---ALADTCARLEAGSGGRLGVGVLDTAGVRTI-GHRLDERFPMCSTFKALAAGVVLARVD -RKQESLGRRVNYTKSDLVTYSPATEKHVEGGMTIAELCEAAITLSDNTAGNLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNQALPGDPRDTTSPRAMAQTLRALTLGDALSATSRA -QLIAWLKANTTGGTRLRAGVPSGWAVADKTGTGDNGTANDVAVLWPPQHAPLIVTVCLTG -AAVARDQQNKIIADVGAAVAD-- ->[subseq from] UPI0012F477AB UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012F477AB ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGAGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075CDA67 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAVSLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADALAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0006526492 ---SVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAERRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q2L9X2_ECOLX ---AMQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q939K2_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAK-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI001248D7FD -----AASFAALERAAGGRLGVCAIDTASGRRA-LHRADERFPFCSTFKAMLSAAVLAQSV -ERPGLLQQRVTYGQADLVDYSPVSARHVGTGMTVAQLCEAAIQYSDNSAANLAMKLIGGP -PAVTAYARSIGDDAFRLDRWETELNTALPGDVRDTTTPAAMAASLRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWPPSRAPIVLAVYYTQ -ARPDAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase LUT-5 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LP01_PSELU ---SFQDRLAKLEQKLNGRLGVCAIDTADGAQL-GYRANERFAMNSTFKVMLASAFLAQSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVATGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ENQQAEARNDVLADAARIVAE-- ->[subseq from] LUT family class A beta-lactamase n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=UPI000F7B0D93 ---SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVATGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ENPQAEARNDVLADAARIVAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CC45B ------TSLAELELAEGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=I0DEV3_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A560D427_AZOBR --kRLADAIAALETRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAILKRVD -EGRERLERRIPVTKADLVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPTAMVHSMERLMLGDALTPASRE -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGARGTANDVGIVWPEGRAPLLIASYLTE -TADGFKERDAIHADVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Shigella sp. SH284 TaxID=1074436 RepID=G3EPW3_9ENTR ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKRSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU15512 TaxID=2015345 RepID=A0A228GHS1_9BURK ------QMLAELERSAGGRLGVCAIDIATGRRV-EHRQNERFPFCSTFKAMLSAAVLAQSV -DRPALLQQRVMYTQADLVNYSPVSGKHVDDGMTVAALCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGEALPAAQRA -QLVAWMRGNKVGDKRIRAGVPARWTVGDKTGTGDYGTTNDAGVVWSPAGASVALAVYYTQ -ARADARAKDDVIASVARIVVRAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264) TaxID=271848 RepID=UPI00098014DD ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTT----------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=3 Tax=Pseudomonas TaxID=286 RepID=N2IP96_9PSED ---SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ENQQAEARNDVLADAARIVAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005368FF4 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -SEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDERIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9002 TaxID=2184558 RepID=UPI000F5F882E ----AATSFDALERAAGGRLGVCAIDTATGRRV-LHRADERFPFCSTFKAMLIAAVLAQSV -TRPALLAQRVTYRQADLVRYSPVTEKHVGAGMTVGELCEATAQYSDNSAANLLMKLLGGP -AAVTAFARAIGDDTFRLDRWETELNTALPGDARDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGAPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVTLAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. JL972 TaxID=2652396 RepID=UPI0012D981AC --eDLTHRFAALEKQLQARLGVAIIDSQSGRQW-LHRADERFPLCSTFKLLAGAAVLRRVD -AGADSLQTRIRYSADDLVTYSPVTEQHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDRFTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAASRG -QLIAWMLASQTGAAKLRAGLPPTWRLGDKTGSGERGTTNEIAVIWPPQRQPVIACVYLTQ -TQASAEERNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. CG23_2 TaxID=1706231 RepID=A0A0S4P1X0_9BURK ------PRLAALEKAAGGRLGVAALDTGNGRQV-GHRADQRFPMCSTFKAIAAAAILAHGK -NVPGLLAQRIRYTKADLVTYSPITEQELDKGMTVAELCEATIQYSDNAAANLLMKLIGGP -AGVTAFARSVGDTTFRLDRWETELNTAIPGDPRDTTTPQAMATLLRRVALDDGLAPAQRD -QLQEWMRGNTTGAARISAGVPAGWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ -AAPDAKANSEILAAATRIVMEDf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. Tr-862 TaxID=2608331 RepID=UPI0014198451 -----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EQPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEATIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASLRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKPKDDVIAAAARIAVA-- ->[subseq from] UPI00132CDA14 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00132CDA14 ---AAEQQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFYSTFKTMLSAAVLARSA -GDAALLQRRIPYAKRDLVRYSPITEKHVGAGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGTAQRA -QLNAWMLGNKTGDARIRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSRNAQARDDVIASAARIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Collimonas sp. OK242 TaxID=1798195 RepID=A0A1H3B4T4_9BURK ----VARQLREIEARSGGRLGVAVLDTHNGQAH-AYRGDERFPMCSTFKLLAAGLTLKRVD -RGQEQLTRRIRYDAADLVAYSPATEKHTGAGMSVAQLCEAAITLSDNTAANLLLHSLGGP -AHLTAYVRSLGDQVTRLDRIEPELNQASPGDPRDTTSPNAMLSTMRQLVLGTALSADARQ -QLTNWLLANTTGDQRLRAYLPAGWRVADKTGSGVHGTTNDIGILFPPDRAPLVVTAYLTG -TKASAATRDAALAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=R4I5F7_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLRGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella derby TaxID=28144 RepID=B6E9R7_SALDE ---AVQQKLAALEKSSGGRLGVALIDTADNTHV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] BETA-LACTAMASE TOHO-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00001D8713 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAERRRDILAAAAKIVTHGf ->[subseq from] beta-lactamase CTX-M-27 n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0000508B91 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKHADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B8BB2FE ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRWEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753EB08 ------TSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFAQRVTYRQADLLEWSPVTEKNVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDETFRLDRWEPELNTALPGDARDTTTPAAMAASLRALAFGDALPAPQRA -QYAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=K7WEV5_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGSYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNW0_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A4D8RNY7_AZOBR --kRLADAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKQVD -EGRERLDRRIRVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTSASRD -QLIAWMVANRTGDKRLRAGLPKGWRIGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TPDTFKERDATHAGVARAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CI-1B TaxID=2511166 RepID=A0A508T6I6_9BRAD --qRLQQAFSRIEQGTGGRLGVAALDSETGLRA-GLRGDERFPMCSTFKALASAAVLRRVD -RGESSLDQRVRFEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILHEIGGP -EGLTSFFRAIGDNVSRLDRWELALNEAVPGDPRDTTSPTAMLKNLQRVLLGDALSATSRK -TLTDWMVANKTGDARLRAGVPADWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ATAPADKCNEAIASVARAVA--- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759A0AE -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAAILLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTINDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Afipia felis TaxID=1035 RepID=A0A380WBR3_AFIFE --eNLKDRISRIEAKVEGRLGVAVLDTGSGRSF-GYRENERFPMCSTFKLMAAAAILKRVE -QKQETLEWRVHFTKSDLVTYSPVTEKHIESGMTVAELCEAAITLSDNTAGNLMLAMLGGP -SGVTAFARALGDPLTRLDRTEPTLNEAVPGDVRDTTTPAAMAENLQKLIFGHALAKASSA -QLQAWLLANKTGDARLRARLPSGWRVGDKTGSGERGSTNDIGILWPPDSAPIIVAAYLTE -TAAPADKRNAALAEVGDAAA--- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=F1DG66_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRE -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q934I0_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTFKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075D220B -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETEVNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKPKDEVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2U8T0X7_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM3_ECOLX ---AVRQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B0FTT8_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFSQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] inhibitor-resistant class A extended-spectrum beta-lactamase CTX-M-219 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000CA39C7A ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVIYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBP4_9BACT ---AVQQKLAALEKSSGGRLGVALIDIADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. GV097 TaxID=2135674 RepID=A0A4R3UTE4_9BURK ------SAFAALEKDLGGRLGISAVNLATGKQV-GHRSGERFPMCSTFKAMVAAAILQRSA -SDPALLKRRISYTKADLVPHAPVTEKHIDRGMTAEELCAAMVQYSDNPAANLLMKVLGGP -EAVTAFARSIGDTDFRLDRWETELNSAIPGDPRDTTTPQAMMRSLQGLVVGDALPAPQRQ -QLKDWLVGNTTGAKLIRAGVPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH -EQADAKYREDIIAGATSTA---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. UFLA03-84 TaxID=418599 RepID=A0A2A2VEY6_9BRAD --qRLQEEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD -HGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCEAAVTLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVTMLKNLQRVMLGDALQAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R9S6T8_KLEPN --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRE -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium sp. LTSPM299 TaxID=1619233 RepID=A0A0D7QH22_9BRAD --qRLQQEFARIELATSGRLGVAALDTETGLRA-SLRGDERFPMCSTFKALATAAVLHRVD -RGESSLDQRVQIQAKDILTYAPITREHVGSDMTLSELCEAAITQSDNTAANLLLRELGGP -AGLTSFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPAAMLKNLQRVVLGDVLQATSRQ -KLTDWMVATKTGDARLRAGAPRDWRVGDKTGTGDRGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPAAKCDEVIANVARAVAN-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092A2AD8 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAEHRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=46 Tax=Bacteria TaxID=2 RepID=A3RJI2_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A386JTM5_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRIEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. HH101 TaxID=1781066 RepID=A0A1E7WQM9_9BURK ------ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP ----ALLKKRVAYRKTDLVTYSPITEKHVGQGMTVAALCEATIQYSDNAAANLLMKQIGGP -AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLQKLLLGDALGAAQRK -QLKDWMLGNTTGDTRIRAGVPAGSLVADKTGTGDYGTTNDIGVIWQPNKAPIVLVVYLTQ -PGKDDKARSEILAEASKIVVEAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000759A40E -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDETFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Cupriavidus basilensis OR16 TaxID=1127483 RepID=H1S0N1_9BURK -haAAQDRLAALESAAGGRLGVAALNTASGAQL-SHRANERFALCSTFKVLAVSAILRRSA -TEGGMLQRRIAYTKAELVAYSPITEKHAGAGLTVAELCAAALQYSDNTAANLLMQLLGGP -AAVTAFARAIGDDTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQRLTLGDALGGAERE -RLVAWMRGNTTGATRIRAGVPADWLVADKTGSGDYGTANDIGVAWPPGKPPIVLAIYFTQ -PGKDAVYRNDVLASAARIAAE-- ->[subseq from] Beta-lactamase LUT-4 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LP00_PSELU ---SFQDRLAKLEQKLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ESQQAEARNDVLADAARIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E2IZP4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075CCDD4 ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETGLNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=5 Tax=Enterobacterales TaxID=91347 RepID=D0EW47_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075E9A0D -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonadales TaxID=72274 RepID=Q4F896_ACIBA --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGGYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAERRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH165 TaxID=1074431 RepID=G3EPV8_9ENTR ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEEHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BHI4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase Toho-1 n=3 Tax=Enterobacteriaceae TaxID=543 RepID=BLT1_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAERRRDILAAAAKIVTHGf ->[subseq from] UPI000FE1826D UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FE1826D ---ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDDRFPMCSTFKVLAAGLVLARVD -RKQENLDRRVSYAKSDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNEALAGDPRDTTSPRAMAQDLRALTLGDALSPASRA -QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPLQRAPLIVTVYLTG -ATVVRDQQNKIIADVGAAVA--- ->[subseq from] UPI001161557A UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001161557A ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGNKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. BH-1 TaxID=2058884 RepID=A0A2N6J8G9_9BURK ---SVVQKLARLEADIGGRLGVSLVDTVHGRQW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGRERLARRIVYRKQDLVPYSPTTGKHTGGALSMAQLCEAAITLSDNTAANLMLTSMGGP -AGLTGFVRTLGDDLTRLDRNEPTLNEAIPGDPRDTTTPAAMTDDLRQVVLGNALAPASRE -QITQWLLANQTGDKRVRAGLPAGWKVGDKTGTGDRGTANDVGVVWTPQGAPLLFAVYLTE -NTAEAARRDAVHAEVGRLIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT103W TaxID=2660640 RepID=UPI00128D1FF4 ------ALLAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP ----ALLKKRVVYRKTDLVTYSPITEKHVGKGMTVAALCEATIQYSDNAAANLLMKQIGGP -AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLQKLLLGDALGAAQRK -QLKDWMLGNTTGDTRIRAGVPAGSLVADKTGTGDYGTTNDIGVIWQPNKAPIVLVVYLTQ -PGKDDKARSEILAEASKIVVEAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000757C214 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5A4UAP9_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRHDVLASAARIIAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Cupriavidus basilensis TaxID=68895 RepID=A0A643FN87_9BURK ---AAQDRLAALESAARGRLGIAALNTANGARL-SHRANERFALCSTFKVIAASAVLQRSA -TQAGLLQRRIAYKKDELVAYSPITEKHVGDGLTVAELCAAALQYSDNTAANLLMKLLGGP -AAVTAFARAIGDDQFRLDRWETELNTALPGDPRDTSTPAAMAASLQRLTLGDALGGAERE -QLVAWMRGNTTGATRIRAGVPADWQAAEKTGSGDYGTANDIGVAWPPGKPPIVLAIYFTQ -PGKDAAYRNDVLASAARIAAE-- ->[subseq from] Beta-lactamase LUT-2 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LNZ8_PSELU ---SFQDRLAKLEQQLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRTPVVLALYSAL -ENQQAEARNDVLADAARIVAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000978064C ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -SEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Providencia rettgeri TaxID=587 RepID=G9JVK3_PRORE --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGGYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000536A31E ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -SEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A3FFV8_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAENRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DV04_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Providencia stuartii TaxID=588 RepID=C5MRF6_PROST --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase CTX-M-2 n=76 Tax=Bacteria TaxID=2 RepID=BLC2_SALTM --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A244B8Y3_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase CTX-M-97 n=1 Tax=Escherichia coli TaxID=562 RepID=BLC97_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A1A5D1T5_9PSED ---STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD -RGEEQLARRIVYGQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLTSLGGP -TGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQPASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPAPAEKRDALLAEVGRLA---- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F8066D5 ------TSFDALERAAGGRLGVCAIDTATGRRV-QYRADERFPFCSTFKAMLIAAVLAQSV -TRPALLVQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGGALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPAGGPVALAVYYTQ -ARADAQAKDDVIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Agona TaxID=58095 RepID=B6E9S0_SALET ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPFAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DK91_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNTVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3X3S6E6_SALER ---SVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN24_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENQTPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2R4G6X4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNW6_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTH -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Jeongeupia sp. USM3 TaxID=1906741 RepID=A0A1D9BCU2_9NEIS ---AASAQFSALEKKYRGRLGVCLLDTASGVQT-GYRADERFAFCSTFKVMLAGAILERST -RVAGLLQQRISYKQSEVVSYSPVSGKHVADGMTVSGLCAAAVQYSDNTAANLLIKLLGGP -AAVTAFARSIGDREFRLDRWETALNSAIPGDPRDTTTPAAMARSLQTLALGDALPLPQRT -QLQDWLRGNTTGDKRIRAGVPAGWRVGDKTGSGDYGTTNDIAVLWPPGRAPVVLAVYFTQ -PDAKAKWQDEVIAAATRIAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. HH105 TaxID=1781067 RepID=A0A1E7VAM9_9BURK --------LAKLEAESGGRLGVAALNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAREP ----ALLKKRVAYRKTDLVTYSPITEKHVGQGMTVAALCEATIQYSDNAAANLLMKQIGGP -AAVTAFARSIGDTEFRLDRIETELNTALPGDPRDTTTPEAMAESLQKLLLGDALGAAQRK -QLKDWMLGNTTGDTRIRAGVPAGSLVADKTGTGDYGTTNDIGVIWQPNKAPIVLVVYLTQ -PGKDDKARSEILAEASKIVVEAf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. SK17 TaxID=2057741 RepID=A0A2K8YN58_9BRAD --qRLQQELARIELATTGRLGVAAFDMETGLRA-NHRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRVQIEAKDILAYAPVTKQHVGTSMTVSELCVAVGTLSDNTAANLLLREIGGP -AGLTAFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVAFGDVLQPASRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIIVTVYLTG -ASAPMDKCNEVIANVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Caballeronia TaxID=2646786 RepID=UPI0013EC416B ---TAEDQLKQLESSAGGRLGVAALNTADGKQV-NYRADERFPLCSTFKLVLVSAVLKQSE -LQKGLLERRIHYTQSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLIKLVGGP -ETVTAFARSIGDTQFHLDRWEPELNTAIPGDPRDTSTPAAMAQSLQRVTLGDALGASQRS -QLQTWLLGNTTGADKIAAALPAHWMVGDKTGSGDYGTTNDIGVIWPPGKPPIVLAIYLTQ -REQGAKARDDVVASAARIVVGAf ->[subseq from] Beta-lactamase n=1 Tax=Cupriavidus sp. SK-3 TaxID=1470558 RepID=A0A069I8A9_9BURK ---AAQDRLAALESAAGGRLGVAALNTASGARI-SHRASERFALCSTFKVLAASAILQRSA -AESGLLQRRIAYTKDELVAYSPVTGKHTGDGMTVSELCAAALQYSDNTAANLLMKILGGP -AAVTAFARSIGDDAFRLDRWETELNTAIPGDPRDTSTPAAMSRSLQRLALGDALGAAERG -RLVAWMRGNTTGATRIRAGVPADWQVADKTGSGDYGAANDIAVAWPPGKPPVVMAIYFTQ -GDKDAAYRNDVLATAARIVAE-- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00004EAC5B --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSCDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAERRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Shigella sp. SH257 TaxID=1074435 RepID=G3EPW2_9ENTR ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) TaxID=258594 RepID=Q6NCV7_RHOPA ---ALADMCARLEAGSGGRLGVGVLDTASGRMI-GHRLDDRFPMCSTFKVLAAGLVLARVD -RKQENLDRRVSYAKSDLVTYSPATEKHVEDGMTIAELCEAAITLSDNTAANLLLASFGGP -AGLTAFARSLGDETTRLDRIETELNEALAGDPRDTTSPRAMAQDLRALTLGDALSPASRA -QLITWLKANTTGGTRLRAGVPPGWTVGDKTGTGGRGTANDIAVLWPLQRAPLIVTVYLTG -ATVVRDQQNKIIADVGAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Cupriavidus basilensis TaxID=68895 RepID=UPI000307A36E -haAAQDRLAALESAAGGRLGVAALNTASGAQL-SHRANERFALCSTFKVLAVSAILRRSA -TEGGMLQRRIAYTKAELVAYSPITEKHAGAGLTVAELCAAALQYSDNTAANLLMQLLGGP -AAVTAFARAIGDDTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQRLTLGDALGGAERE -RLVAWMRGNTTGATRIRAGVPADWLVADKTGSGDYGTANDIGVAWPPGKPPIVLAIYFTQ -PGKDAVYRNDVLASAARIAAE-- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=J7KCB4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1E1G7Y0_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGGGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera sp. N03-0461 TaxID=280338 RepID=Q6IUM8_9ENTR ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -RQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI000486BDD9 --qRLQQEFARIELATSGRLGVAVLDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRVQIEAKDILAYAPVTKGRVGSAMTLSELCAAAIKLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia sp. MSMB1589WGS TaxID=1636425 RepID=UPI0007B93839 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRADERFPFCSTFKMMLSAAVLARSA -DDAALLQRRIPYAKRDLVRYSPITERHVGASMTVAELCAATLQYSDNTAANLLIDLLGGT -QAVTAYARSIGDATFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLAGDALGAAQRA -QLNAWMLGNKTGDARLRAGVPAGWRVADKTGTGDYGTGNDIGVAYPPDRAPIVFVVYTTM -RSQNAPVRDDVIAAAARIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. AP07 TaxID=1144304 RepID=J2ZR77_9CAUL -----SRSIIALEARSGGRLGVAALDTQTGATF-AHRADERFAMCSTFKALVAGLVLARVD -QGKERLDRRIAYGKDVLVTHSPVTERHVGDSMTVGALCEATVTVSDNAAANLLLDTFGGP -SAVTAFVRALGDKVTRLDRREPELNVVRPGEQHDTTSPRAMLGSLRALTLGAALSPASRQ -QMVDWLLANQTGDKRLRAGLPAGWKVGDKTGSWGDGTTNDIAVIWPPGRAPILIAAYLTQ -AKVDSAARDAVIAEVARIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=Q7X209_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDESFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A1G5NI34_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas sp. B29 TaxID=95607 RepID=UPI000348E3EA ---ELADPCARLESGSGGRLGVCMLDTATGVVR-GHRLDDRFPLCSTFKVLAAGLVLSRVD -QHQEQLDRRVNYQKQDLVTYSPATEKHVADGMTMAELCAAAITLSDNTAGNLLLASFGGP -PALTAFARGLGDDVTRLDRNETELNEALPGDPRDTTTPRAMAATMRKLVLGDVLSPASRE -QLVAWLKANTTGGTRLRAGVPRGWVVGDKTGTGERGTANDAAVLWPPQRPPVIVAVYLTG -ATVAREQQNATIAAAGAAVVATy ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A560CLJ2_AZOBR --kRLADAIAALERRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRTIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLDDALTPASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE -TADAFKERDAIHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q936V5_PROMI --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDFLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0H3YEU2_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGEYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A023PYF0_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVIAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z3GWX4_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVYYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium pachyrhizi TaxID=280333 RepID=UPI0012FAEFCB --qRLQQEFARIELATSGRLGVAVLDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRVQIEAKDILAYAPVTKGRVGSAMTLSELCAAAIKLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005317EB8 ---AAERQLRELESTFDGRLGFVALDTATGARV-AYRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q937J1_ECOLX -----QQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera sp. N03-0462 TaxID=280336 RepID=Q6IUN6_9ENTR ---AVQQKLATLEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIRPTDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Kluyvera TaxID=2619995 RepID=Q5PU98_9ENTR ---AVQQKLATLEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIRPTDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium TaxID=374 RepID=UPI000465B64E --qRLQQELARIELATTGRLGVAAFDMETGLRA-NHRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRVQIEAKDILAYAPVTKQHVGTSMTVSELCVAVGTLSDNTAANLLLREIGGP -AGLTAFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVAFGDMLQPASRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIIVTVYLTG -ASAPMDKCNEVIANVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A4U6S4A9_BRAEL --qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRMQIEAKDILAYAPVTKAHVGSAMTLSELCAAAVTLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVELNEAMPGDQRDTTSPVAMLKDLQRVLLGDVLSAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGAFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAIAN-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092DDC43 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPQAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TS44 TaxID=477228 RepID=I4JJC6_PSEST --eDLTQRFAELEKQLDARLGVAIIDSQSGRQW-LQRADERFPLCSTFKLLAGAAVLLRVD -VGADSLQTRIRYGADDLVTYSPVTERHVDDGMTLAALCEAAITLSDNTAGNLLLRHLGGP -GAIGDFARTLGDHHTRLDRWETELNEARPGDPRDTTTPAAMAANLQRLVLGDSLSAPSRD -QLIAWMLASQTGAAKLRAGLPQDWRIGDKTGSGERGTTNEVAVIWPPQRKPVIACVYLTQ -TQASADARNAALAAIGRALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A077JMT3_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAKLSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759515E -----ATSLAELERAAGGRLGVHALDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDRRIRVGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARADAKRKDDVTAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EA7F0FC ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000EA7F100 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYSPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A0D1MKS1_BRAEL --qRLQQELARIELATTGRLGVAAFDMETGLRA-NHRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRVQIEAKDILAYAPVTKQHVGTSMTVSELCVAVGTLSDNTAANLLLREIGGP -AGLTAFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVAFGDMLQPASRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIIVTVYLTG -ASAPMDKCNEVIANVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A4D8PNY7_AZOBR --kRLTDAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRPIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPTAMVHSMERLMLGDALTPASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TPDTFKERDAIHAGVARAVAD-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000A1A157B ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. K1S02-6 TaxID=2320866 RepID=A0A418XI78_9PSED -----HLQLQQLERAFNGRLGLFALNTGHGAQL-GYRATERFPVCSTFKVLLAAAILQRST -QTPGLMQQRIQYIKRDLVSYSPISEKHLETGMTVAELCAAAVQYSDNTASNLLMKLLGGP -AGVTAYARSIGDAEFRLDRWETDLNTAIPGDPRDTSTPEAMGRSVQRLALGDALQAPQRE -QLQTWLRGNTTGATRIRAGVPSAWQVGDKTGTGDYGTTNDIAVLWPPQRAPVVVAVYVTQ -QAQDAKARNDVVASAARIVV--- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F09695E ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia cepacia complex TaxID=87882 RepID=UPI000754C3B0 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKTMLGAAVLARSV -EHPGLLQQRVTYAQADLVSSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNV9_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTGIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Microvirga subterranea TaxID=186651 RepID=A0A370HUN4_9RHIZ ---DPKARLADLERRHGGRLGVAILDTQTGRRI-EHRAGERFAMCSTFKAVAAALVLARVD -RGEERLDRHMTFTKADLVRWSPVTEKHVGTGMTMAQICEAAITSSDNTAGNLMLESFGGP -AALTAYARTLGDSMTRLDRIETALNEATPGDPRDTTTPAAMLGTMEKLLLGEALSGPSRE -QLTAWLVANKTGDRRIRAALPRDWRVGDKTGTGDNGAANDIAILWPPGRGSILIAAYYAE -AKATDEQRNAVLADVGRVAA--- ->[subseq from] class A extended-spectrum beta-lactamase CTX-M-235 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001413AE1F ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D1MAH3_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRT -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. JKS000303 TaxID=1938747 RepID=A0A2A9LTL7_9BURK ------TSFAALERAAGGRLGVCAIDAASGRRA-QYRADERFPFCSTFKTMLSAAVLAQSV -ERPGLLQQRVTYGQGDLVNYSPVSSKHVGTGMTVAALCEAAIQYSDNSAANLLMKMIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASVHVLTLGDALPGVQRA -QLVAWLRGNKVGDKRIRAGVPTGWQVADKTGTGDYGTTNDAGVMWPPSGAPIVLVVYYTQ -TRADAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A2Z4TXQ8_SERMA ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A124PVX4_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWEIEVNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKDEVIAAAARIAVAAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007535DF2 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWEIEVNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKDEVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B8BB34A ---AVQQKLAALEKSSGGRLGVAAIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sullae TaxID=50338 RepID=UPI000B351DFD --dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYHESKLVSYSPETEKHVGGEMSVAELCKAAITLSDNTAGNLLLESFGGP -EALTKWLRSIGDRSTRLDRWETALNEGKKDDPRDTTTPDAMLDTLGNVALGSVLSEPSRN -TLIGWMMANTTGGARLRAGLPGSWKVGDKTGTGNXG------------------------ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=L8B2Q9_PROMI --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium tropiciagri TaxID=312253 RepID=UPI00067B29C3 --qRLQQEFARIELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQVEAKDILAYAPVAKQHVGSGMTLAELCGAAITLSDNTAANLLLREIGGP -AGLTSFFRTIGDNISRLDRWEVELNEAVPGDPRDTTSPVAMLKNLQRVVLGDILQANSRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=A0A3W6LF28_SALER ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNATGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=4 Tax=Burkholderia pseudomallei TaxID=28450 RepID=H9CTS4_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS96.2 TaxID=1680160 RepID=A0A1Q5QVQ9_9BRAD --qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMLSAAVLHRVD -RGESSLDQRMQIEAKDILAYAPVAKQHVGSAMTVAELCEAAITLSDNTAANLLLREIGGP -AGMTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTGPVAMLKNLQRVVLGDVLQANSRQ -RLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPTEKCNEVIANVARAVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A5B0KZZ9_AZOBR --kRLADAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRTIPVTKADMVPYAPFAETRLGGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE -RLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TADTFKERDATHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Afipia felis TaxID=1035 RepID=A0A090MSH8_AFIFE --qDLKSKISRIESRVKGRLGVAVLDTGSDRRF-GYRKDERFPMCSTFKLMAAAAILKRVE -QGQETLERRVHFSQSDLVTYSPATEKHLESGMTVAELCEAAITLSDNTAGNLMLGMLGGP -PGVTAFARALGDPLTRLDRTELALNEAVPGDPRGTTTPAAMAEDLRKLMFGGALAKASSE -QLKAWLLANKTGDARLRARLPAGWRVGDKTGSGERGSTNDVGILWPPDAAPLIAAVYLTQ -TAASMNERNEALAAVGEAVAAAf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. R5 TaxID=1855320 RepID=A0A1G6R4M3_9BRAD --qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRVQIEAKDILAYAPVTKAHVGSAMTLSELCAAAITLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDQRDTTSPVAMLKDLQRVVLGDVLQTVSRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q8VKT5_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ -PDQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001505B76 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B0BF90_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVTAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNDTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A2V4G2K8_SERMA --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRPEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=B3LE90_9ENTR --nSVQQQLKALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTRGf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F2520FC ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYSPIAEKHVNGTMSLAELSAAAVQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH58 TaxID=664962 RepID=A0A2S1XDI8_9PROT --kRLADAIAALETRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAILKQVD -EGRERLDRRIRVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMGRLMLGDALTPASRE -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE -TADSFKDRDATHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=B3LE88_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=UPI0013E0E4D9 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTTFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia violaceinigra TaxID=2045208 RepID=A0A2D2DED5_9BURK ----TQARLAALEKAAGGRLGVAAVDTGNGRQM-GHRASERFPMCSTFKAIASAAILAHAR -NVPGLLEQRIRYTKADLVTYSPITEQELDKGMTVAELCEATIQYSDNAAANLLMKLIGGP -AGVTAFARSVGDTTFRLDRWETELNSAIPGDPRDTTTPEAMATLLRRVALDDGLPPAQRD -LLQAWMRGNTTGAARIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ -AAPDAKANSDILAAATRIVMEE- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=UPI000E2E674D ---STLERLKQLERDSGGRLGVAVLDTGNGRRF-GLREDERFPLCSTFKLLLAACVLARVD -RGEEQLARRIVYGQADLVEYSPVSERHIGQPMSVADLCEAAITLSDNGAANLLLASLGGP -AGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPAPAEKRDAVLAEVGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiaceae bacterium 16 TaxID=1619952 RepID=A0A0F0FEC0_9BURK ---AAQDRLAALESAAGGRLGVAALNTANGARI-SHRASERFPLCSTFKVLAASAILQRSA -AESGLLQRRIAYTKDELVAYSPVTGKHAGEGMTVSDLCAAALQYSDNTAANLLMHILGGP -AAVTAFARSIGDDAFRLDRWETELNTAIPGDPRDTSTPASMSRSLRRLALGDALGAAERG -RLVAWMRGNTTGATRIRAGVPADWQVADKTGSGDYGAANDVAVAWPPGKPPVVMAIYFTQ -GDKDAAYRNDVLATAARIVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Microvirgula aerodenitrificans TaxID=57480 RepID=A0A2U3TGW8_9NEIS ----LTTRVAAIEQSLDARLGVAVIDTGTGREW-AYRGNERFPMMSTFKPLLCSLLLSQVD -QGREMLDRRIEIRPDDLLEHAPVAGKHVGKAMSLGELCEAAITQSDNTAANLVLERVGGP -ARVTAFLRSLGDSKTRLDRNEPTLNEARPGDERDTTMPVAMAGSLKQLVLGQTLSPASRR -QLTDWLVANRTGDAKIRAGLPAGWRVGDKTGSGANGSMNDVAVIWPAGRKPVVLAIFITG -TGASVAARNAAMADITRALVD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q2XT31_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia oklahomensis TaxID=342113 RepID=A0A381IF48_9BURK ---AAERQLSELESSFGGRLGFVALDTATGARI-AHRAAERFPFCSTFKTMLSAAILARSA -GDATLLQRRIPYAKRDLVSYSPVTEKHVGDGMTVAELCAAALQYSDNTAANLLIALLGGP -QAVTAYARSIGDTTFRLDRRETELNTAIPGDERDTTTPAAMAASLRRLLVGDALGAAQRA -QLDTWMLGNTTGAARIRAGVPADWRVADKTGTGDFGTGNDIGVAYPPSRAPIVIVIYTTM -RDKNAQARNDVLASAARIAARTf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ86_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SGPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ21_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTDGw ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Salmonella infantis TaxID=595 RepID=A0A5X6CG23_SALIN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFSRAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2H4FY00_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDRTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Microvirgula sp. AG722 TaxID=2183901 RepID=A0A329BCF5_9NEIS ----LTTRVAAIEQSLNARLGVAVIDTGTGREW-AYRGNERFPMMSTFKPLLCSLLLSQVD -QGREMLDRRIEIRPDDLLEHAPVAGKHVGKAMSLGELCEAAITQSDNTAANLVLERVGGP -ARVTAFLRSLGDSKTRLDRNEPTLNEARPGDERDTTMPVAMAGSLKQLVLGQTLSPASRR -QLTDWLVANRTGDAKIRAGLPAGWRVGDKTGSGANGSMNDVAVIWPAGRKPVVLAIFITG -TGASVAARNAAMADITRALVD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075C1044 -----AATFAALERAAGGRLGICAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria IOP40-10 TaxID=396596 RepID=B1FL89_9BURK -----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EQPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPVGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI000571A012 --qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMASAAVLHRVD -RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP -AGFTSFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ -KLIDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIADVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z1VQJ7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVIYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM5_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLSHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0U2T6D5_PROMI --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQSVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000978A2A6 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTAPPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. 117 TaxID=1125973 RepID=UPI000493BAFE --eALTASLRGIEAKTGGRLGVALIDGTDGAVE-GYREAERFPMCSTFKALAAAAVLARVD -AGSERIDRVVRYTRADLVTYSPAAEKHVDDGMTLDALCEAAVTLSDNTAGNLLLKAIGGP -AGLTAYARSLGDRLTRLDRWETALNEAAPGDERDTTTPAAMAGNLRRLVLGDALQPASRA -RLTGWLVGNKTGDTRLRAGVPGDWRVGDKTGTGENGTANDVGIAWPPRRAPLVVAIYLTQ -SRGDAASRNAAIAEAARAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q934I1_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTT -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A4GWT3_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A3N2SDD8_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAENRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A235HDW6_AZOBR ---RLADAIAALEKRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAVLKRVD -DGRERLDRPIPVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDQKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD -RLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE -TADGFKERDAIHAGVGRAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN23_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SNKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei (strain 1710b) TaxID=320372 RepID=Q3JFF0_BURP1 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei (strain K96243) TaxID=272560 RepID=UPI00032D6826 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum frisingense TaxID=92645 RepID=UPI0005876466 ---SIVQKLARLEADIGGRLGVSLVDTVHGRQW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGRERLARRIVYRKQDLVPYSPTTGKHTGGALSMAQLCEAAITLSDNTAANLMLASMGGP -AGLTGFVRTQGDELTRLDRNEPTLNEAIPGDPRDTTTPAAMTADLRQVVLGNALAPASRE -QITQWLLANQTGDKRVRAGLPAGWKVGDKTGTGDRGTANDVGVVWTPQGAPLLFAVYLTE -NTAEAARRDAVHAEVGRLIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia singularis TaxID=1503053 RepID=A0A118DPT1_9BURK ---DAQRALRELEASFDGRIGVAALDTATNAKI-AYRADERFAFCSTFKMMLSAAVLARSA -AEPDLLPRRIVYAKRDLVEYSPITGKHAGAGMTTAELCAAALQYSDNTAANLLISLLGGT -QAVTAYARSIGDAEFRLDRRETELNTAIPGDLRDTTTPSAMAASLRRLLLGDALGQAQRE -QLNAWMLGNTTGNERIRAGVPPAWRVADKTGTGDYGTANDIGVLYPPGRAPVVLAIYTTG -RAQQARARNDVIASAARIVARAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0P0IV60_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEHTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000753B7E5 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTSRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q842S3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYSPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4BV97_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYSPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q939N4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] UPI00144A4CA8 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI00144A4CA8 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=B1H5V3_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=4 Tax=Burkholderia pseudomallei TaxID=28450 RepID=A8ELB7_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007621BEF -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVTWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVVAAAARIAVATf ->[subseq from] CTX-M-14 Class A Beta-Lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005D2D2AF ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=29 Tax=Enterobacterales TaxID=91347 RepID=Q9L5C8_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A081Y9J5_9PSED ---STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD -RGEEQLARRIVYSQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -SGLTDWLRSTGDNVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPAPAEKRDALLAEVGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZW7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTDGw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAF8_KLEPN --nAVQQKLAALEKSSGGRLGVPLIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium manausense TaxID=989370 RepID=A0A0R3DZN2_9BRAD ------EAIKQLEQKSGGRLGVSVLDTNSGVPI-HHRGDERFPMCSTFKVLAAAAILKDVG -SKLEGLERRVRIEQADLVEYSPVTSKHVGGEMSLRELCEAAITLSDNTAGNALLKNIGGP -AGLTSFARSLGDETTRLDRIETELNEAAPGDPRDTTTPNAMAANFRRLLLGDALVPEGRD -QLIKWLVANKTGDSRLRAGLPQGWRVGDKTGSGQRETANDVAIVWPPERSPIIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=H7CHS5_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEATLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase Toho-1 n=3 Tax=Escherichia coli TaxID=562 RepID=UPI0001B04C53 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTAPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAENRNDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E0AF02_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F1DTB3_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDRTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRHDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI00119DB802 --kRLADAIAALERRSGGRLGVAVLDTGTGQRF-GHRADERFPMCSTFKFLLAGAILKRVD -EGRERLDRHIPVTKADLVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD -RLVAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TADSFKERDAIHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A0N7I8Z4_AZOBR --kRLAGAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFAMCSTFKFLLAGAILKQVD -EGRERLDRRIPVSKADMVPYAPFVETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE -TPDSFKERDAIHAGVARAVAD-- ->[subseq from] Beta-lactamase LUT-3 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LNZ9_PSELU ---SFQDRLAKLEQKLNGRLGVCAIDTANGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLMYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ENQQAEARNDVLADAARIVAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000977F335 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRITARAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas TaxID=1073 RepID=UPI00115DF2E5 ---AIAARFAELEARSGGRLGVCVLDSSNGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD -RKQESLDRRVSYTKSDLVTYSPATETRVEGGMTIAELCEAAITLSDNTAGNLLLGSFGGP -AGLTAFARSLGDQTTRLDRIETELNEALPGDARDTTSPRAIAQDLHALALGDALTPSSRA -LLVGWMKANTTGGARIRAGVPSGWSVADKTGTGERGTANDIAVLWPPQRAPLIVTVYLTG -ATVSRDQQNRLIAAAGAEA---- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. PI1 TaxID=1582493 RepID=UPI0005B9DD60 ---STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD -RGEEQLARRIVYSQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -SGLTDWLRSTGDNVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPAPAEKRDALLAEVGRLA---- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00087267AC --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKLLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAXLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L053_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIRAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=B6E9R9_SALET ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTPAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAF9_KLEPN ---AVQQKLAALEKSSGGRLGVPLIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas fungivorans (strain Ter331) TaxID=1005048 RepID=G0AJJ5_COLFT -----AGQLRQIEAKSGGRLGVAILDTVTGQSH-SYRGDERFPMCSTFKLLAAGLTLHRVD -QGREQLARRIRFEKADLVPYSPATEKHAGGDMSVAELCEATLTLSDNTAANLLLHSFGGP -PQLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPSAMLSTMQQLLLGNALSADSRK -QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGAYGSTNDIGMLFPPGRAPLLVAAYLTG -TKASEATRNATLAEVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Edaphovirga cremea TaxID=2267246 RepID=UPI000DF01D96 ---EIQQKLADLEKSSGGRLGVALINTADNSRI-VYRGDERFPMCSTSKVMAASAVLKQSE -TQKDVLNQRVKISKSDLVNYNPITEKHLDTGMTLGELSAATLQYSDNTAMNKLITHLGGT -QGVTAFARSIGDKTFRLDRTEPELNTAIPGDERDTSTPLAMAESLRKLTLGDALAKPQRA -QLVEWLKGNTTGAASIRAGLPETWVVGDKTGSGDYGTTNDIAIIWPTNKAPLILVTYFTQ -TEQNAKSRKDVLADAARIVTQ-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=S0F1K6_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=UPI000641F99A ---AIAARFAELEARSGGRLGVCVLDSSNGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD -RKQESLDRRVSYTKSDLVTYSPATETRVEGGMTIAELCEAAITLSDNTASNLLLGSFGGP -AGLTAFARSLGDQTTRLDRIETELNEALPGDARDTTSPRAIAQDLHALALGDALTPSSRA -LLVAWMKANTTGGARIRAGVPSGWNVADKTGTGERGTANDIAVLWPPQRAPLIVTVYLTG -ATVSRDQQNRLIAAAGAEA---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. KJ006 TaxID=416344 RepID=I2DXP2_9BURK -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G0XMH2_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTQNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F05A0E5 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSV -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0005D8B0F4 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Skermanella stibiiresistens SB22 TaxID=1385369 RepID=W9GWJ4_9PROT ------ADLARIETGISGRLGVAVHDTGTGRRL-EYRSGQRFPMCSTFKVVASAALLTRVD -AGREKLDRRIRFGAGDLVTYSPVTKDRVGGDMTLAELCEAGITQSDNTAANLLLANIGGP -AGMTEYARSLGDAMTRLDRIETELNESTPGDPRDTTTPAAMTETLRKLVLGDALSPASRD -HLAAWLVANKTGDARLRAGVPKDWRVGDKTGSGDHGTANDIGVFWPPGRAPLVVSVYLTE -TKASMDDRSAAIAAVARVVT--- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0003C0A7A9 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -SEPALLQRRIAYAKGDLIRYSPIIEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Cupriavidus basilensis TaxID=68895 RepID=A0A0C4YHK8_9BURK ---AAQDRLAALELAAGGRLGIAALNTANGARL-SHRANERFALCSTFKVIAASAVLQRSA -TQAGLLQRRITYKKDELVAYSPITEKHVGGGLTVAELCAAALQYSDNTAANLLMKLLGGP -AAVAAFARTIGDDQFRLDRWETELNTALPGDPRDTSTPAAMAASLQRLTLGDALGGVERE -QLVAWMRGNTTGATRIRAGVPVDWQVADKTGTGDYGTANDIGVAWPPGKPPIVLAIYFTQ -PGKDTAYRNDVLASAARIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ16_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPITEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI0003A98B5D --kRLAGAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFAMCSTFKFLLAGAILKQVD -EGRERLDRRIPVSKADMVPYAPFVETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE -TPDSFKERDAIHAGVARAVAD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075C0533 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKTMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETEVNTALPGDLRDTTTPAAMAASIRALTLGDALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A060DLH1_AZOBR --kQLADAIAALEKRSGGRLGVAVLDTGTGQCF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRTIPVTKADMVPYAPFAETRLGGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE -RLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TADTFKERDATHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas fungivorans TaxID=158899 RepID=A0A419U0J9_9BURK ----VARQLRQIEAKSGGRLGVAILDTVTGQSH-AYRGDERFPMCSTFKLLAAGLTLHRVD -QGREQLARRIRFEKADLVPYSPATEKHVGGDMSVAELCEAPLTLSDNTAANLLLHSFGGP -PRLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPNAMLSTMQQLLLGNALSADSRK -QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGGYGSTNDIGMLFPPGRAPLLVATYLTG -TKASEATRNATLAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A4D8QHC2_AZOBR --kRLADAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFPMCSTFKFLLAGAVLKRVD -EGRERLDRPIPVTKADMVPYAPFAETRLDGLPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGNALTPASRE -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TPDTFKERDATHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q0GM96_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTQAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas heilongjiangensis TaxID=1387883 RepID=A0A2N7TJF2_9GAMM ----LTDKVIEIEERLGARIGVAVLDTQTGHRW-EHRGNERFPMSSTFKTLACGAVLARVD -TGEEALDRRIRFAAGDVVTYSPVTEHRVGGDMTLAELCEATITTSDNTAGNLILETLGGP -GGLTEFMRSLGDTTTRLDRWETELNEATPGDPRDTTTPVAMADSLHALLFEERLSPSSRD -QLAAWLVANTTGDAKLRAGLPRNWRIGDKTGGGGHGTNNDVAVIWPPDREPAIVSVYLTE -SEASFDDRNAAIAEIGRLVK--- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F06407E ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTAM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=13 Tax=Proteobacteria TaxID=1224 RepID=H6V563_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter cloacae TaxID=550 RepID=C5MRF5_ENTCL --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTETTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDB361 ---SLEAAFKELEKATGARLGVSAHDTGSGKRI-DYREKELFAMCSTFKFFAAAAILARVD -QKKEQLDRIVTYKKSDLVDYSPVTEKHVGEGMSLAAICEAAITYSDNTAGNLMLDALGGS -KGLTDYARSLGDTITRLDRRETELNEATPGDPRDTTTPAAMRENLEKTVLGTALSEQSRK -QLADWLIGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD -PKGTADSRNAIHQKVASLIAEH- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8RKB1_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=7 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A223B3Y7_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MAG2_ECOLX ---AVQQKLAALEKSSGRRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=F1CLM9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELIAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. Y2R2 TaxID=2562282 RepID=A0A5C1NN05_9GAMM --dELSRALEDTEARLGARLGVSILDTETGKLW-QHRNDERFPLNSTFKALASAAVLARVD -AGEEDLDRRITFTESDLVDWSPVTEKHVGDEMTLGELCQAALQWSDNSAANLVLDAIGGP -QGLTEYMRTLGDDVTRLDRWETELNEGTPGDPRDTSTPEAMRQSLQKVLLGEALSAESRQ -QLEDWMLGDKVADDLLRAAIPQDWRIADKTGAGGYGSRNIVAVIWPPQRQPVIAAIYITE -TEASMDESNVAIADIGRALVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Chimaeribacter arupi TaxID=2060066 RepID=A0A2N5ENL6_9GAMM --dTLTAQLAELERNANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV -TQPALLEKRIRYDRAALQSYAPVTGKHLAGGMTVAELCAAAIEWSDNTAANLLLTEIGGP -QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ -QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ -PKADAEARRDVLATATRLVLASf ->[subseq from] class A beta-lactamase n=1 Tax=Chimaeribacter arupi TaxID=2060066 RepID=UPI000C7D9850 --dTLTAQLAELERSANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV -TQPALLEKRIRYDRAALQSYAPVTGKHLAGGMTVAELCAAAIEWSDNTAANLLLTEIGGP -QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ -QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ -PKADAEARRDVLATATRLVLASf ->[subseq from] class A beta-lactamase n=1 Tax=Azohydromonas lata TaxID=45677 RepID=UPI00082ABC71 ---ALTRALPALEQRLGGRLGVYVLDTQSGRQW-TWRADERFPMCSTFKVLACGAVLARVD -AGEEALGRRIRFKAEDLVTYSPVTELHASGDMPLGALCEAAMTRSDNTAANLILRSLGGP -AAVTAFARTLGDPATRLDRWETALNEARPGDPRDTTTPAAIGRNLRALLLGPHLAPASRE -QLARWLQANRTGDARLRAGLPAAWRVGDKTGSGDFGTSNDVAVIWPPGRAPVIASVYVTE -CGAAFEDRNAAIADVARAL---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium erythrophlei TaxID=1437360 RepID=A0A1H4WJF5_9BRAD --rQLQEEFARIELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAMLHRVD -RGESSLDQRVQVEAKDILAYAPVAKQHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVALNEAVPGDPRDTTSPVAMLKSLQRVVIGDVLQAASRQ -KLVDWMVANKTGDARLRAGVPRDWKVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAH-- ->[subseq from] Beta-lactamase n=11 Tax=pseudomallei group TaxID=111527 RepID=H9CTS3_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=I0DH95_ECOLX ---AVQQKLAALEKSSEGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKLSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria MEX-5 TaxID=396597 RepID=B1T356_9BURK -----ATSFAALEHAAGGRLGVCAIDAASGRRA-QHRADERFPFCSTFKAMLSAAVLAHSV -ERPGLLQQRVTYGQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKPKDDVIAAAARIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM4_ECOLX ---AVRQKLAALEKSSGGRQGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1W5RXG1_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841F2B4 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNYSPVSGRHVATGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTSYARSIRDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLAVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5D8SME3_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHXNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAXRRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase LUT-6 n=1 Tax=Pseudomonas luteola TaxID=47886 RepID=C0LP02_PSELU ---SFQDRLAKLEQKLNGRLGVCAIDTADGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVSTGMTVAELCAAGIQYSDNTAANVLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTSTPQAMAMSLQRLALSDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRRAPVVLALYSAL -ESQQAEARNDVLADAARIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Nitrobacter sp. 62-13 TaxID=1895797 RepID=A0A1Q3K7H5_9BRAD ---RFVEELKRLEGGSGGRLGVAMLDTGTGQCV-GHRMDERFPMCSTFKVLASGAVLHSVD -AGKESLARRIYFTDSDLVTHSPETQKHVGPVMTVAELCEAAMTLSDNTAGNLLLASIGGP -QGLTAFVRSLGDEVTRLDRIETELNEAAPDDLRDTTTPDAMAADLRALALGDVLSTKSRT -QLVSWLAANTTGSKRLRAGLPAGWRVGDKTGTGEQGTANDVAVIWPPDRAPFVITAYLTG -AAAPVERQDAVMAAVGRAVT--- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F0705D2 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLERREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium uaiense TaxID=2594946 RepID=UPI0013B8E911 --qRLQQEFARIELATTGRLGVAALDMETGLRA-SRRGDERFPMCSTFKAMASAAVLHRVD -RGESSLDQRVQVEAKDILVYAPVAKQHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRREVELNEAVPGDPRDTTSPVAMLKDLQRVVLGDVLQPMSRQ -KLTDWMLANKTGDARLRAGLPRDWRVGDKTGSGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. ABCPW 14 TaxID=1637860 RepID=A0A132CES7_9BURK ---AAERQLGELESSFDGRLGFVALDTATGARI-AHRANERFPFCSTFKTMLSAAILARSA -GDATLLRRRIPYAKRDLVSYSPITEKRVGDGMTVAELCAAMLQYSDNTAANLLIALLGGP -QAVTAYARSIGDTTLRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGAAQRA -QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM -RDKNAQARDDVLASAARIAARTf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DD804EF ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q3HLW4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI001439BB01 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAXLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000EF21488 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0009765C3C ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000110AD3 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTAPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAERRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT75_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAATVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTDGw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q2XPY6_SALET ---DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVIYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersiniaceae TaxID=1903411 RepID=UPI00093367D9 --dTLTAQLAELERNANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV -TQPALLEKRIRYDRAALQSYAPVTGKHLAEGMTVAELCAAAIEWSDNTAANLLLTEIGGP -QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ -QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ -PKADAEARRDVLATATRLVLASf ->[subseq from] Beta-lactamase CTX-M-14 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) TaxID=1125630 RepID=UPI000572ABBE ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Trinickia symbiotica TaxID=863227 RepID=A0A2N7X035_9BURK -----KTKLAAIEKQFGGRLGVYALDTGSGTEI-RHRADERFPFCSTFKMVLASAVLAKSV -QEPGLMEQRMQYAQSDLVSYSPISRKHVADGMTVAELCRAAVELSDNTAANQLIKLLGGP -AAVTAFARSIGDNTFRLDRWETELNTAIPGDPRDTTTSRAMAHTLQAVALGNALPETQRD -TLQTWLRGCQTGAKRIRAAVPAGWDVGDKTGTGDHGTANDVAVIWPPSRKPIVLAIYHTQ -EKPDTRGRDEAIADAARVVVA-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F04F1D1 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTAM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=E3PQJ5_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAALLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z3GWX3_KLEPN --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGIGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N077_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001186BE4F ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD849D4 ---SLEAAFKELEKATGARLGVSAHDTGSGKRI-DYREKELFAMCSTFKFFAAAAILARVD -QKKEQLDRIVTYKKSDLVDYSPVTEKHVGEGMSLAAICEAAITYSDNTAGNLMLDALGGS -KGLTDYARSLGDTITRLDRRETELNEATPGDPRDTTTPAAMRENLEKTVLGTALSEQSRK -QLSDWLIGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD -PKGTADSRNAIHQKVASLIAEH- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A345IT60_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGGYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=A0A4Z0IKT2_9PSED ---STLERLKQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACVLARVD -RGEEQLARRIVYSQADLVEYSPVSERHVGQPLSVAELCEAAITLSDNGAANLLLASLGGP -AGLTDWLRSTGDDISRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDILQPASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPAPAEKREAVLAEVGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTV9_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILATYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5P8NAT3_KLEPN --eDVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I3VNW5_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -AQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVDDKTGSGDYGTTNDIAVIWPQGRAPLALVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI000E0C0F01 --kRLADAIAALEKRSGGRLGVAVLDTGTGQRF-GQRADERFPMCSTFKFLLASAVLKRVD -EGRERLDRRIAVTKADMVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRD -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLITSYLTE -TPDSFKERDATHAGVARAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Shigella sp. SH202 TaxID=1074432 RepID=G3EPV9_9ENTR ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGQ -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000755DDCF -----AATFAALERAAGGRLGVCAIDTASGRRA-RHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNYSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETEVNTALPGDLRDTTTPAAMAASIRALTLGDASPPAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADARAKDEVIAAAARIAVAAf ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q5KT52_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTESTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Class A beta-lactamase n=1 Tax=Trinickia symbiotica TaxID=863227 RepID=A0A2T3Y1E2_9BURK ----SRTKLAAIEKQFGGRLGVYALDTGSGTEI-RHRADERFPFCSTFKMVLASAVLAKSV -HEAGLMQRRIQYAQSDLVSYSPISGKHVADGMTVDELCRAAVELSDNTAANQLIKLLGGP -AAVTAFARSIGDKTFRLDRWETELNTAIPGDPRDTTTPTAMAHTLRAVALGNALPDMQRD -MLQTWLRGCQTGAKRIRAAVPAGWDVGDKTGTGDHGTANDIAVIWPPSRKPIVLAIYHTQ -EKPDTRGRDEAIADAARVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. B65 TaxID=137708 RepID=UPI0003497D75 ---AISARLARLEADVGGRLGVSLVDTAGARQW-GYRADERFPMCSTFKWLAAAAVLRRVD -EGREQLTRRIVYHQRDLIPYSPTTGKHVGGTLSLAQLCEAAVTLSDNTAANLMLASMGGP -AGMTAFVRTLGDALTRLDRNEPALNQAVPGDPRDTTTPAAMTADLQRLVLGDALTPASRA -QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTPQGKPLLFAVYLTE -NAADDARRDALHAEVGRLIAQ-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00052AC912 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPLVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005314B91 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPLVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Q8EPK3_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDDTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAEHRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. lig30 TaxID=1192124 RepID=A0A063B5R1_9BURK -----ANSFAELERAAGGRLGVCAIDTGSGRRA-QHRADERFPFCSTFKTMLGAAVLARSV -ERPALLQQRVTYGPGDLVRYSPVTEMHVGTGMTVAELCAAAIQYSDNSAANLLMKLIGGP -SGVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASVRALALGDALPAAQRA -RLVEWLCGNKVGDKRFRAGVPPGWQVGDKTGTGDYGTTNDAGVMWPPSRAPIVLAVYYTQ -ARADATAKDDVIASAARIAVAAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=UPI0005F591D3 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] UPI0011C3427D UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0011C3427D ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. CY15W TaxID=2692172 RepID=UPI00136D9D7A -----TAQLALLEKESGGRLGVAALNTGDGRQL-LHRADERFPVCSTFKMMLSAAVLARDP ----ALLKKRIPYEKSDLVPHAPITSKHVGEGMTVAELCEATLQYSDNPAANLLMKQLGGP -AAVTAYARSIGDSEFRLERWETELNTAIPGDPRDTTTPEAMARSLQKLVLGDALPPTQRK -QLKDWMLGNTTGATRIRAGVPPGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ -PGKDDKSHPEIHGEVAKVVIEAf ->[subseq from] Beta-lactamase n=1 Tax=Collimonas sp. PA-H2 TaxID=1881062 RepID=A0A2A9K3V0_9BURK ---AIVEQLRQIEAKSGGRLGVAIFDSGSGQTY-AYRGGERFPMCSTFKLLASALVLKRVD -QGKEQLARRIRYQKADLVPYSPVTEQHTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP -AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGRNLSTSSRE -QLTDWLLANKTGDKRLRALLPAGWRVADKTGTGDQGTANDIGMLLPPGRAPLLVASYLTG -APAPAAARDAVHAQVGRLAA--- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia sp. BDU5 TaxID=1385590 RepID=UPI000758BCDB ---AAERQLGELESSFDGRLGFVALDTATGACI-AHRADERFPFCSTFKTMLSAAILARSA -GDATLLRRRIPYEKRDLVSYSPITEKHVGEGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDTMFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGVAQRA -QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM -RDKNAQARNDVLASAARIAARTf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. BDU6 TaxID=1385591 RepID=A0A1B4FLI7_9BURK ---AAERQLGELESSFDGRLGFVALDTATGACI-AHRADERFPFCSTFKTMLSAAILARSA -GDATLLRRRIPYEKRDLVSYSPITEKHVGEGMTVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDTMFRLDRRETELNTAIPGDERDTTTPAAMAASVRRLLVGDALGVAQRA -QLDTWMLGNTTGGARIRAGVPADWRVADKTGTGDYGTGNDIGVAYPPNRAPIVIVIYTTM -RDKNAQARNDVLASAARIAARTf ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A2R3SK14_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAESIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQW5_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPNAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2H4FXZ9_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDDTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0008A254D4 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNNNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Cy-637 TaxID=2608327 RepID=UPI00141E4CFF ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFPLCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGGYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNAAIAAVARIVTATf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00053205A8 ---AAERQLRELESTFDGRLGFVAFDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ49_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A173GH11_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A060KQ56_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L009_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ03_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZD6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZZ1_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L064_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A223A5R2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. ESBL358B15_13_3E TaxID=1563525 RepID=A0A0A0R195_9ESCH ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAAR------ ->[subseq from] Beta-lactamase CTX-M-14 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) TaxID=1125630 RepID=UPI000572AB9D ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGAGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q6DQV0_ENTCL ---DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1T3S7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L035_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. PBS-H4 TaxID=434008 RepID=UPI001315E90D ----LARQLAEIEKKIGGRLGVHVLDTANGRHA-GHREDERFALCSTFKFLAAALVLARVD -QGKERLDRRVVYSRDDLVTYSPATEKHAGTDMTMAQLCEAAVTLSDNTAGNLMLASFGGP -AGLTAFMRSLGDAHTRLDRIETALNEAREGDPRDTTTPAAMVASMQKILLGDALSTASRA -QLLQWLDDNKTGGQRIRAGVPADWKVGDKTGTGENGAANDIAILRPPGRSPILLSVYLTE -TRASIADRNAAHAAVAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ62_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNAAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTNGw ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain DX-1) TaxID=652103 RepID=E6VH66_RHOPX ---AIAARFAELEARSGGRLGVCVLDSSNGRMI-GHRLDERFPMCSTFKVLAAGLVLARVD -RKQESLDRRVSYTKSDLVTYSPATETRVEGGMTIAELCEAAITLSDNTAGNLLLGSFGGP -AGLTAFARSLGDQTTRLDRIETELNEALPGDARDTTSPRTIAQDLRALALGDALTPSSRA -LLVAWMKANTTGGARIRAGVPSGWIVADKTGTGERGTANDIAVLWPPQRAPLIVTVYLTG -ATVSRDQQNRLIAAAGAEA---- ->[subseq from] class A beta-lactamase n=1 Tax=Chimaeribacter arupi TaxID=2060066 RepID=UPI000C7BF24E --dTLTAQLAELERNANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQRSV -TQPALLEKRIRYDRAALQSYAPVTGKHLAEGMTVAELCAAAIEWSDNTAANLLLTEIGGP -QSITKLARSLGDDKTRLDRWEPELNTAIPGDERDTSTPRAMARNLQHLALGEALPQAQQQ -QLIGWLKNSQTGAKSIRAGVPAGWDVGDKTGSGDYGTTNDLAVIWPPHGKPLVLAIYFTQ -PKADAEARRDVLATATRLVLALf ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia sprentiae WSM5005 TaxID=754502 RepID=A0A1I9YU65_9BURK ---EAQRRLGALESATGGRLGVAALNTADGTQV-QHRADERFPFCSTFKVMAASAILKRSE -TENGLRRQHIAYTKDELVAYSPITAEHAGTGMTVSELCAAALQHSDNTAGNLLIKMLGGP -AAVTAFARSIGDDPFRLDRWETELNTAIPGDPRDTTTPAAMAGSLQRLALGDALGAPERA -MLIEWMRGNTTGAAKIRAGVPAAWSVADKTGGGDYGTTNDIAVMWPPGKPPIVLAVYFTQ -PDKDAPVRNDVVATAARIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTK6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000C27EF6E ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTAM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000976DA72 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFYSTFKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQF0_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVSYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Ap-962 TaxID=2608333 RepID=UPI00141F3E55 ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFPLCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGGYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNAAIAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTQ9_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000893E48E ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q8RLA1_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRRESELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2R3SK19_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8376 ---AVQQKLAALEKSSTGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTAPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. L27(2015) TaxID=1641858 RepID=UPI00131B1F60 -----TAQLATLEKNSGGRLGVTALDTANGMLI-RYRADERFPFCSTSKVMVAAAILERST -RQTGLMHKRIHYAKSDLVHYSPISEKHVADGMTVAELCAAAIQYSDNSSANLLMKILGGP -PAVTAFARSIGDKEFRLDRWETELNSAIPGDRRDTTTPAAMAISLRSLMLGDILPAAQRQ -QLQDWLRGNTTGANRIRAGVPADWRVGDKTGTGDYGTANDIAVLWPPARKPIVLTIYHTQ -LQTDAKPRDDVIAAATRIVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00061C60C8 --dALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALSPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ27_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHIGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B2CR57_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTELTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. RA8 TaxID=662548 RepID=UPI0013186E7B ---DLARQFAGIEKKTGGRLGVHVLDTANGRRA-GHRQDERFAMCSTFKFLAAALVLARVD -QGKEKLDRRLTYSRQELAPHSPATEKHAGGDMTMAQLCEATITLSDNTAANLMLASFGGP -AGLTAYMRSLGDPHTRLDRIEPGLNEARAGDPRDTTTPAAMVGSMQKILLGDALSPGSRA -LLLQWLDDNKTGGERIRAGLPADWKVGDKTGTGENGAANDIAILRPPGRPPILLSVYLTE -TKASMADRNAAHAAVAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A159ZKX3_ECOLX ---DVQQRLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P8NAV8_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00128E86B6 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Kluyvera cryocrescens TaxID=580 RepID=Q8VVP3_KLUCR ---SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP -QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA -QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ -PQPEAESRRDVLASAAKIVTE-- ->[subseq from] class A extended-spectrum beta-lactamase KLUC-5 n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000C285D5D ---SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP -QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA -QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ -PQPEAESRRDVLASAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTK2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0H4IS11_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A193H694_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L007_9BACT ---DVQQRLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3B8DM63_9ENTR ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00123BE7BC ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Q1MQ14_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=K9UTH3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8G9E9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ68_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQB4_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZA5_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZB3_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQC7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A5JUR0_PROMI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ75_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0H4IVL4_KLEOX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZA9_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=33 Tax=Bacteria TaxID=2 RepID=Q6BBP7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ89_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ07_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D097FA4 ---SVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCATSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAENRNDILAAAAKIVTHGf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F2BD9C8 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=25 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2R3SK21_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9142 TaxID=2184573 RepID=A0A3N8AJI1_9BURK -----ATSFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAQSV -ARPGLLQQRVMVGQSDLVNYSPVSGKHVGTGMTVAALCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPGAQRA -QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLVVYYTQ -ARADAKAKDDVIAAAARIAVATf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000F05815C ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPIAEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium 64-17 TaxID=1895814 RepID=A0A1Q4DJN8_9RHIZ ---SFTTTVRTLERRSGGRLGVAVIDTQSGKQS-GWRADERFPMCSTFKLVAAAAVLRRVD -RGAEQLDRRVVIRHRDIITYSPVTKERIGQAISIAELCEAAVTLSDNTAANLILKSLGGP -RAFTAFARSLGDHATRLDRIEPHLNSAIPGDRRDTTTPAAMAKTVRALVLGDALSAASRV -QLVAWLRGNKTGDTRLRAGLPDGWICGDKTGTGVRGTSNDIGVLWPPQQAPLVVTAYLTG -STGDAKARDAILADVARAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=J7IB33_ECOLX ---SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP -QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA -QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLVLVTYFTQ -PQPEAESRRDVLASAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=C5IUN2_ENTCL ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLALGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. TaxID=1890675 RepID=A0A2E7NXD3_9BURK ---ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP -AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. DXTD-1 TaxID=2495592 RepID=A0A429WLF3_9BURK ---SAEAQLAALESSVGARLGVAALDTGSGARV-QHRATERFALCSTFKTMLAAAILARSA -RDSSLLERRVSYSRSDILTNSPITEKNLGQGMTVSALCAATMQYSDNAAANLLMKILGGP -AAVTAFARSIGDQTFRLDRWETELNSAIPGDLRDTTTPEAMAASLQRLVLGDALSAAQRS -QLEAWLLGNTTGAARIRAGVPADWKVGDKTGLGSYGTNNDTGVLWPPSGAPVVLAVYLTF -PKEDAPARNDVIASAARIVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum huttiense TaxID=863372 RepID=A0A4P7AC91_9BURK ---ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP -AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00111D507D ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAGMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQE2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVAWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L001_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAKSRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9KVM2_9BURK -----ATSFAALEHAAGGRLGVCAIDTASGRHA-QHRADERFPFCSTFKAMLGAAVLARSV -EQPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGGYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKAKDDVIAAAARIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1LLA5_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8W9A7_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTL3_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A2H5BF61_PSEAI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C337F0C --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLQKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0P0HZ66_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGNSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp9031 TaxID=2184566 RepID=A0A3P0MST6_9BURK ------TSFVALERAAGGRLGVCAIDTASGRRA-QHRASERFPFCSTFKAMLGAAVLAQSV -ERPGLLQQRVMIGQSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA -QLVAWLRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVIWLPSRAPIVLVVYYTQ -TRADAKAKDDVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=U3N3M8_ECOLX ---NVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] LUT family class A beta-lactamase n=1 Tax=Pseudomonas sp. LTJR-52 TaxID=2479392 RepID=A0A3G2NCV6_9PSED ---SFQDRLAKLEQKLNGRLGVCAIDTADGAQL-GYRANERFAMNSTFKVMLASAFLARSQ -DEPGLLEERLTYTRADLVTYSPVTEKHVVTGMTVAELCAAGIQYSDNTAANMLMKKLGGP -EAVTAFARSIGDTHFRLDRWETELNSAIPGDPRDTNTPQAMAMSLQRLALGDMLAADKQH -QLQAWLKGNTTGGKRIRAGVPAGWQVGDKTGTGDYGSANDVAILWPPRHAPVVLALYSAL -ENPQAEARNDVLADAARIVAE-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00050F52B9 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q83ZQ7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001C05CC7 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q66W71_KLEPN ---DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZY9_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT80W TaxID=2666084 RepID=UPI0012B0D30A ------AQLARLEQESGGRLGVAALNTADGRQV-LHRGDDRFPFCSTFKMMLAAAVLAREP ----SLLKRRIQYEKSDLVPHSPVTGKHVADGMTVAELCEATLQYSDNAAANLLMKQIGGP -AAVTAFARSIGDNEFRQERWETELNSALPGDTRDTTTPLAMARSLQKLVLGEALPQASRR -QLKDWMVGNTTGNARIRAGVPAGCLVADKTGAGDYGTVNDIAVIWPPGRAPIVLAVYLTQ -PGKDDKGRGDIHAEVAKVVIEAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella infantis TaxID=595 RepID=C3VMM9_SALIN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRHDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Herbaspirillum TaxID=963 RepID=A0A495Q0T5_9BURK ---ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP -AGMTRFVRSLGDDLTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0009776230 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTAPPGDERDTTTPAAMAASVHRLRVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Class A extended-spectrum beta-lactamase CTX-M-154 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A650DI89_KLEPN ---DVQQKLAKLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTW6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. DN04 TaxID=2561932 RepID=A0A4Y9SJK4_9BURK --------LARLEQECGGRLGVAALNTGDGRQL-LHRADERFPMCSTFKMMASAAVLARDP ----ALLKKRIRYDKADLVPHAPVTGKHVGEGMTVAELCEATLQYSDNPAANLLMKELGGP -AAVTAFARGIGDTDFRLERWETELNSAIPGDPRDTTTPLAMAKSLHKLVLGDALPPPARK -QLKDWMLGNTTGAARIRAGVPSGWPVADKTGAGDYGTVNDIAILWPPGKAPIVLAVYVTQ -PGKDDKAHPEVHGEVAKIVIEAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ24_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] Beta-lactamase CTX-M-14 n=2 Tax=Klebsiella pneumoniae subsp. pneumoniae (strain HS11286) TaxID=1125630 RepID=UPI000572AB9F ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGAGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRADVLASAARIIAE-- ->[subseq from] Beta-lactamase n=668 Tax=root TaxID=1 RepID=C7S9T0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] UPI00126783C6 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI00126783C6 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella sp. ARS06-441 TaxID=474576 RepID=A8IW71_9ENTR ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDDTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L043_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGATNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTC7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWDVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL05_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas humi TaxID=1826671 RepID=UPI000853BF7E ---STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD -RGEEQLARRIVYGQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -AGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDILQPASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDLAILRPPGRSPILVAAYLTG -SPAPAEKRDALLAEVGRLA---- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00050F99D3 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAEVCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q0Z958_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=Q6ZXB6_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZB6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=Q75NB4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D0F40D4 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGAETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8692 TaxID=2607910 RepID=UPI00141DC001 ---EAQAELVALEAAAGGRLGVGAIDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK -NVPGWLDQRVRYTKADLVTYSPITEKHLDDGMTVGELCAATIQYSDNAAANLLMAKIGGP -GGVTGFARSMGDTVFRLDRWETELNTAIPGDPRDTTTPAAMAALLRRVALDDGLPAAQRD -QLQNWMRGNTTGAARIRAAVPASWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ -ADAQAKANSDILAQATRIVMAAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A2Z4Q2E9_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRHVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia sp. R10 TaxID=2082624 RepID=UPI000D03C4D9 ---DVQQKLAELERQSGGRLGVALINTADNSQL-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L046_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL25_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL06_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=A0A0E1UDG8_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0009786D27 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRRESELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=11 Tax=Enterobacteriaceae TaxID=543 RepID=Q845L5_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTQ6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L004_9BACT ---DVQQKLAELERQSGGRLGVALINTAGNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ83_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKESDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=B0LV41_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum seropedicae TaxID=964 RepID=UPI0008481BFC ---ALTARLSRLEADIGGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -QGQEQLTRRIVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP -AGLTRFVRTLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLTQWLIANQTGAKRVRAGLPASWKVGDKTGTGRLGTANDIGVVWTAQGAPLLFAVYLTE -NAATDAGRDAVHAEVGRLI---- ->[subseq from] Beta-lactamase n=2 Tax=Halomonas elongata TaxID=2746 RepID=E1V6J8_HALED ----LEAELASLEQRLDARLGVAVTDTGSGRHW-GHREDERFPMASTFKVLACAALLDRVD -AGQEELQRRVIYEQDDLVTYSPVTKEHVGEPMTLGSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFTRSLGDDMTRLDRWETKLNEAIPGDPRDTTTPAAMAADLQALFLGDRLSEESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGAHGSTNNVAVAWPSDGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLVAR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ63_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGAMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ96_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASATKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00123BFF3F ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PPPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans TaxID=80842 RepID=A0A328IZU6_9BURK ---AISARLARLEADVGGRLGVSLVDTAGARQW-GYRADERFPMCSTFKWLAAAALLRRVD -EGREQLTRRIVYHQRDLIPYSPTTGKHVGGTLSLAQLCEAAVTLSDNTAANLMLASMGGP -AGMTAFVRTLGDALTRLDRNEPALNQAVPGDPRDTTTPAAMTADLQRLVLGDALTPASRA -QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTPQGKPLLFAVYLTE -NAADDARRDALHAEVGRLIAQ-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BF5B6 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAYVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000994A0FA ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGPMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A5B8KR99_ENTCL ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAANIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WYA8_9BACT --eQFATELQRLERDSGGRLGVVLLDTATGKRA-GHRMDERFPMCSTFKVLAASAILHNVD -AGKESLERRVYFNETDLVTYSPETKKHVGPSMTIAELCKAAITLSDNTAGNLLLASIGGP -KGFTDFARSLGDKMTRLDRIETALNEALPDDPRDTTTPNAMASDLQSLVLGKTLSAKSRA -QLVEWLAANTTGGKRLRAGLPTGWHVGDKTGTGDRGTANDIAVIWPTGRAPVIVTVYLTG -ATASADQQSAVIAGVGRAV---- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132F8656 ---AVQQKMAAREKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0009266322 -----QQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKFIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPADPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAEHRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A8BHZ3_ENTCL ---SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SQHDLLNQRIEIKKGDLTNYNPIAEKHVGRSMSLSELSAAALQYSDNVAMNKLIAQLGGP -QGVTAFARKIGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA -QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ -PQPEAESRRDVLASAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT87_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVSGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH20 TaxID=652754 RepID=A0A2U1WWS0_9PROT ---ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAVLKAVD -QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP -AGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ -TAEGFKQQDSIHAEVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9P045_9BURK -----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -ERPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKPKDDVIAAAARIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI0013FDC1CD -----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -ERPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKPKDDVIAAAARIAVA-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001073F173 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAERRRDVLASAAKIVTD-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI000A1DFC96 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRASIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A482GLY3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium paxllaeri TaxID=190148 RepID=UPI0011478E8E --qRLIDEIKRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKALAAAAILARVD -AGKEQLTRRITFEASALVTYSPVTEKHVGGDMTLAEICEAAVTLSDNTAGNLLLAALGGP -PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPNAMASSLQALVVGTALSAPSRE -QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPHGKAPIVITGYLTG -ATVPAAQQNAVWASVARAVS--- ->[subseq from] Uncharacterized protein n=1 Tax=Glaciimonas sp. PCH181 TaxID=2133943 RepID=A0A2T6F253_9BURK ---SAQMQLAALETQTGDRLGVHAINTADGGQL-GHRADERFPFCSTFKVLAISAILARSA -HEDGLLQQRIHYSPSEMVSYSPITERHVADGMTIAELCAAALQYSDNTAANLLIKALGSP -ASVTAFARTIGDNTFRLDRWETALNSAIPGDPRDTTTPAAMAHSLQRLALGDGLAPPQRA -QLQQWLQGNTTGAKRIRAGVPADWQVGDKTGSGDYGATNDVAVLWPPGKPPIIVALYFTQ -REKEAKSREDVLASAARIVVKAf ->[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A2TLT3_SALTM ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q5NQR5_9BACT ---AARAQLGQLEKRFGGRIRVFALNTADGSGL-SYRADERFPVCSTFKVLAAAALLRKSG -RVPGLMQQRIKYQQGNLVSHSPITEKHVSGGMTVAELCAAAIQYSDNTAGNLMLRMLGGP -SALTAFSRSIGDSQFRLDRWETALNTAIPGDSRDTSTPRAMALNLERLVLGDALKSQQRK -QLREWMLGNTTGTKRIKAGLPANWLIGDKTGGGDYGTANDVGVLWPPHRKPIIVAIYTTQ -PKKDATAQNEVIADVARIVVK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ67_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGAMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQC0_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQM-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI00052A4BEB ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYSPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUJ3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0P0GRE4_PROMI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSCDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=A0A2U9NK71_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSCGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ60_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAERHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. MHTC-1 TaxID=2495593 RepID=A0A3R9ZDQ1_9BURK ---ALSKQLADIEKASGGRLGVGVLDTGNGRRA-GHREDERFPLCSTFKFLAAAFVLARVD -QRKERLERRVVYGPRDLVTHSPVTEKHADGTMTVAQLCEATLTLSDNTAANLLLQSFGGP -KGLTAFMRSIGDAKTRLDRFETALNEARPGDLRDTTTPAAMSRSMQKILLGDILTQPSRA -QLLQWLDGNKTGDERIRAGLPADWKVGDRTGSGQNGTTNDIAILRPPGRAPILLSVYLTE -TAAAPAARNAALASVAAAVA--- ->[subseq from] class A extended-spectrum beta-lactamase CTX-M-226 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0010A73CF3 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0K0TQJ3_PROMI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127R6W9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=60 Tax=Bacteria TaxID=2 RepID=Q0GA57_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=UPI001009EB2B ---QLIEAFEQLELKSAGRLGVSVLDTTTGAQI-HHRGDERFPMCSTFKVLAAAAILKGVG -SKLEGLERRVRIEQADLVEYSPVTSKHVGGDMSLRELCEAAITMSDNTAGNALLKNIGGP -AGLTSFARSLGDKTTRLDRIETELNEATPGDPRDTTTPNAMATNFRRLLLGDVLLTEGRD -QLGKWLIANKTGDSRLRAGVPKGWRVGDKTGAGEHGTTNDVAIVWPPERSPVIIAVYLTG -SALDPNGRNDVIASVGSAVAK-- ->[subseq from] UPI00144A4CB9 UniRef100 entry n=2 Tax=unknown TaxID=N/A RepID=UPI00144A4CB9 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTASTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=S6FS81_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGNGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075803D1 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRVLTLGDALPAAQRA -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPILLTVYYTQ -ARADAKAKENVIAAAARIAVAAf ->[subseq from] class A beta-lactamase n=1 Tax=Duganella ginsengisoli TaxID=1462440 RepID=UPI0012D4AAB8 --qSATDKLAALEKSAGGRLGVAVLDTGSGRQV-LHRADERFAFCSTFKTMVAAAILARSE -KEPDLLARRIRYTQADLVTYSPETEEHVKDGMTVAELCEATIQVSDNSAANLLMKVLGGP -PAVTAYARSIGDQQFRLDRWETELNSAIPGDTRDTTTPAAMMQSVNRLLLGDALAAPQRK -QLVDWMVGTLTGNERIRAGSPAGATVADKTGTGAYGVTNDIGVVWPQGRAPLVVVVYYAG -PDKDSKARSDVVATATKIALD-- ->[subseq from] class A extended-spectrum beta-lactamase CTX-M-234 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00140EA5CE ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFPMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ38_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIEKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8374 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTASTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DDD15F7 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLALGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH361 TaxID=1074437 RepID=G3EPW4_9ENTR ---DVQQKLAELERQSGGRLGVALINTADNSRI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVT--- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001185F320 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWLKGNTTGAASIRAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8D3A8_KLEPN ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLEQSE -TQKQLLNQPVEIQPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDHTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B0ZTA3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPNAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas sp. OK412 TaxID=1801619 RepID=A0A1I1MPX9_9BURK ----IARQLRQIEIRSGGRLGVAILDTLTGQSH-AYRGDERFPMCSTFKLLAAGLTLKRVD -QGQEQLARRIRYEAAELVPYSPVTEKHVGGGMSIAELCEATLTLSDNTAANLLLHSFGGP -ARLTAYVRSLGDKATRLDRIEPDLNQATPGDPRDTTSPGAMLSTMHQLLIGNALSADSRK -QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGAYGSTNDIGILFPPDRAPLLVASYLTA -TKASEATRNAALAEVGRLAA--- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001185801F ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTM0_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -RLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6R3N1_ECOLX ---DVQQKLAELEQQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSCDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z1VQJ2_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRIEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001C05CF6 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9GMV9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIHAGLPASWVVGDKTGSGGYGATNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8694 TaxID=2609280 RepID=UPI001420A245 ---EAQAELAALEAAAGGRLGVGAIDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK -HVPGWLDQRVYYTKADLVTYSPITEKHLDDGMTVGELCAATIQYSDNAAANLLMAMIGGP -GGVTGFARSMGDTVFRLDRWETELNTAIPGDPRDTATPAAMAALLRRVALDDGLPAAQRD -QLQNWMRGNTTGDTRIRAAVPASWAVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ -ADQQAKADSEILAQATRIVMAAf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013D370D8 ---AVQQKLAALEKSSAGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=Q934I2_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRRESELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia mallei TaxID=13373 RepID=UPI000E6CAD3D ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASAPRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT65_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRANERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTT7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAERHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQD7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1W6AKZ1_PSEAI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRXVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia singularis TaxID=1503053 RepID=A0A238H4H6_9BURK ---DAQRALRELEASFDGRIGVAALDTATNAKI-AYRADERFAFCSTFKMMLSAAVLARSA -AEPDLLPRRIAYAKRDLVEYSPITGKHAGAGMTTAELCAAALQYSDNTAANLLISLLGGT -QAVTAYARSIGDAEFRLDRRETALNTAIPGDLRDTTTPSAMAASLRRLLLGDALGQAQRE -QLNAWMLGNTTGNERIRAGVPPAWRVADKTGTGDYGTANDIGVLYPPGRVPIVLAIYTTG -RAQQARARNDVIASAARIVARAf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C294F2D ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGXYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1B2MYQ2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAATVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0S1Z227_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFAQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6TGK7_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVIAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQ33_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIATD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTF3_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDEMFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZX0_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQHSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0005370826 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLMALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATWIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A1KQS3_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Methyloligella halotolerans TaxID=1177755 RepID=A0A1E2RWN7_9RHIZ --dELAKRFAELESSTDGRLGVAVFDSGSAKRS-SYRGDERFPMCSTFKYLAAGAVLKRVD -EGKASLDEKIPITKADMLEYAPVTEKHIGEEMSLEALCEAIVTWSDNPAANLVLKRLGGP -EAVTEFARSLGDEVTRLDRYELALNDVPPGDTRDTTSPRAMANNLDRLVRTDALSDASRR -QLIAWLVDNHTGDNRIRAGLPKDWKVGDKTGTGPRGSTNDVGVAWPPDGKPVFIAVYLTD -TEMPIAKREAVLASVARTVAE-- ->[subseq from] Beta-lactamase (Fragment) n=36 Tax=Bacteria TaxID=2 RepID=A0A0F6T6C9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase CTX-M-1 n=16 Tax=Enterobacterales TaxID=91347 RepID=BLC1_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=A0A127MX92_9PSED ---STLERLKRLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD -RGEEQLARRIVYGQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -TGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDILQPASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPAPAEKRDALLAEVGRLA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5B7LK14_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKTVTD-- ->[subseq from] Beta-lactamase n=14 Tax=Gammaproteobacteria TaxID=1236 RepID=Q842A4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. T529 TaxID=2491343 RepID=A0A561C1H7_9BURK ----AQAQLAALERSVGGRLGVVAFDTATGARV-QHRATERFPMCSTFKMMASAAILDRSS -REPGLLERRVSYARSDILPNSPVTEKHLGEGMTVSALCAATIQYSDNAAANLLMKMLGGP -SAVTAFARSIGDPVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS -QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF -PAQDAPGRNDVIASAARIAVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=E5Q8Z8_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A173GH44_ECOLX ---DVQQKLAELERQSGGRLGVALINTADTSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1S6KJQ6_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQVGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia pseudomallei TaxID=28450 RepID=H9CTS7_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFYSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Bradyrhizobium TaxID=2631580 RepID=UPI0009F9D49D --qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRID -RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP -AGLTGFFRTIGDNVSRLDRWELALNEAVSGDPRDTTSPVAMLKDLQRVVLGDVLSAASRQ -KLIDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTAYLTG -ASAPIEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium lablabi TaxID=722472 RepID=A0A0R3M8N7_9BRAD --qRLIDEIKRLESESGGRLGVCVLDTATDTRH-VHRGDERFPMCSTFKALAAAAILARVD -AGKEQLTRRITYDASALVTYSPVTEKHVGDGMTLAEICEAAVTLSDNTAGNLLLAALSGP -PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPSAMASSLQALVVGTALSAPSRE -QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITGYLTG -ATVPAAQQNAIWASVARAVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8693 TaxID=2609000 RepID=UPI0014202A1A ---EAQARLAALEVAYGGRLGVGALDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK -NVPGWLEQRVRYTKADLVTYSPITEKHLDDGMTVGELCAATIAYSDNAAANLLMAKIGGP -GGVTGFARSVGDTVFRLDRWETELNTAIPGDPRDTSTPAAMAALLRRVALDDGLPPAQRD -QLQNWMRGNTTGDTRIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPRGAPVVLALYYTQ -ADPQAKANSEILAAATRIVMGAf ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A3RLQ6_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=F8UXB4_PROMI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0S1Z1Z9_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTTFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2Z5WNL3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGSYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ42_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNAAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI000F814F13 -----ATSFAALEHAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -DRPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -ARADAKPKDDVIAAAARIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140CVN0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -TQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAG0_KLEPN ---AVQQKLAALEKSSGRRLGVPLIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT79_9BACT ----VQRKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. (strain M1) TaxID=95619 RepID=W5IZ45_PSEUO ---STLERLQQLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD -RGEEQLARRIVYSQADLVEYSPVSERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -AGLTDWLRSTGDDVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLADVLQPASRD -RLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPVPAEKRDALLAEVGRLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas caseinilytica TaxID=438744 RepID=UPI0007E5B626 ----LEAELASLEQRLDGRLGVTVTDTGSGRHW-GHREDERFPMASTFKVLACAALLDRVD -AGQEELQRRVIYEKDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQVLFLGDRLSKESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLVTR-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. UFLA 03-321 TaxID=1783512 RepID=A0A1R1QKS8_9BRAD --qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRID -RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP -AGLTGFFRTIGDNVSRLDRWELALNEAVSGDPRDTTSPVAMLKDLQRVVLGDVLSAASRQ -KLIDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTAYLTG -ASAPIEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Andreprevotia lacus DSM 23236 TaxID=1121001 RepID=A0A1W1XZV0_9NEIS ---KAAAALAALEQQAGGRLGVYAWDTGSGAIV-NHRADQRFPFCSTFKLMLAGAILARSA -QQPALLTKRIHYRRAQLISHSPQTGQHLDDGMTVAELCAATLQYSDNAAANLLLAQLGGP -AALTAFARSIGDRSFRLDRTEPTLNTAVPGDVRDTTTPAAMARSLHALTLGNALPAAQRQ -QLQDWLRGNTTGDKRIRAGVPAGWAVGDKTGSGAYGTTNDIAVLWPASSAPIVLAIYYTQ -DQPKADWRDAVLAQATRAVLQ-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZZ5_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDCAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6C8RAC7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASXAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum aquaticum TaxID=568783 RepID=A0A225SVK4_9BURK ---TLTAPLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -QGREQLERRIVYRQQDLVPYSPTTGKHTGGELSVAQLCEAAVTLSDNTAANLMLASMDGP -AGLTRYIRTLGDELTRLDRNEPTLNEATPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLTQWLVANQTGDKRVRAGLPKNWKVGDKTGTGRLGTANDVGVVWTDKGAPLLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DAC7B93 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLERTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas eurihalina TaxID=42566 RepID=A0A5D9D8P0_HALER ----LEAELASLEQRLDGRLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD -AGQEELQRRVIYEQDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQALFLGDRLSEESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=E2ITW2_SHISO ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAA------- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella flabilis TaxID=463014 RepID=A0A193GEX3_9BORD ---ALHAAFGSLEKSYASRLGVCAIDTANGREI-RHRAEERFPFCSTFKAMAAAAVLARAS -ADPGLLARRIPYTRADLVTYSPITEKHAGAGMTVAELCAATVQYSDNTAGNLLIKLLGGP -PALTAFMRGVGNRSFRLDRWETDLNTAIPGDPRDTATPSDMAHSLNKLVLGGALPAAGRA -QLKEWLVGNTTGDRRIRAGVPDGWQVGDKTGTGSYGTANDIAVLWPPARPPIVLAVYSTQ -PSKTGKPSDALIAEATRVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. Root655 TaxID=1736578 RepID=A0A0Q8FY08_9CAUL -----SRSIIALEARSGGRLGVAALDTQTGATF-AHRGDQRFAMCSTFKALVAGLVLARVD -QGKERLDRRLRYGKQALVAHSPATERHVGDGMTIGALCAATVTLSDNAAANLLLDGFGGP -PALTAFLRGLGDPATRLDRREPELNEARPGDPRDTTTPTAMLGSLRALTLGAALSPASRA -QLVAWLVANQTGGARLRAGLPTGWRVGDKTGSDGEHTTNDIAVIWPPGRAPILITAYLTQ -AKVDSAGRDAVIAEVARIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BFZ7_ECOLX ---XVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGXYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M-9 extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001D34111 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2R3SK13_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVIWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN25_9ENTR --nSVQQQLEALEKSSGGRLGVALINTAGNSHI-LYRADERFAKCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=A0A1G9HRK0_9PSED --eAFERRLARIEDDIGGRLGVALLDLGTGLRA-GWRQDERFPMCSTFKFLAAAAILARQD -QGLDSLERRVKFAAADLVEYSPATGPRADGEMTLAELCEAAVTLSDNTAGNLMLNSLGGP -EGLTAFARSLGDDITRLDRYETALNEALPGDPRDTTTPAAMLADMRELLLGTALSPASRE -RLLGWLVANKTGDARLRAGLPKDWRVGDKTGSGDRGTANDIAILWPPRREPMLVTVYLTG -SDADMNRRNAAIAEVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. CF079 TaxID=1882774 RepID=A0A1G7CTL4_9BURK ---NLSKQLADIEKASGGRLGVGVLDTANGRRA-GHREDERFPLNSTFKFLAAALVLARVD -RRKEQLERRVVIRPGDLVTYSPVTEKHVGAGMTVAELCEATMTLSDNTAGNLLLASFGGA -PGLTAFMRSIGDTNTRLDRTEPALNEGRPGDPRDTTTPAAMTRSMQKILLGDVLSPASRA -QLLQWLDANKTGDERIRAGVPADWKVGDKTGSGEN-GANDVAILRPPGRAPILLSVYLTQ -TRAPAAVRNRALASVAAVAAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTM4_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETLRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. C9 TaxID=142585 RepID=A0A2A6NN08_9BRAD --kRLQEEFARIELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRVQVEAKDILAYAPVAKQHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVALNEAVPGDLRDTTSPVAMLKSLQRVVIGDVLQAASRQ -KLMGWMVANKTGDTRLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPTDKCDEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=2 Tax=Halomonas caseinilytica TaxID=438744 RepID=A0A1M6VA64_9GAMM ----LEAELASLEQRLDGRLGVTVTDTGSGRHW-GHREDERFPMASTFKVLACAALLDRVD -AGQEELQRRVIYEKDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQVLFLGDRLSKESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLVTR-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A2Z6TLY2_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNQVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENGMAGAARIAVGTf ->[subseq from] Beta-lactamase n=1 Tax=Bosea sp. Tri-44 TaxID=1972137 RepID=A0A4Q1VT64_9BRAD --eEVREALFALDRRHGGRLGVAILDSGSGRVI-AHRGQERFAMCSTFKFVAAAFVLARVD -RGEESLDRRVSYTKTDLVTYSPVTEKHVDTGLTVAELCDAAVTLSDNAAGNLLLDSFGGP -KGLTSYMRSLGDDSSRLDRRELELNEATPGDPRDTTTPVAMAQILRQTVLGAALSPASRH -QLTAWLVANKTGDKRLRAGVPKGWRVGDRTGTGSNNATNDIGVIWPPGRAPLIVTAYYAE -SRGSLPEREAVLAEVGRLAT--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8362 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCGTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTU2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTASPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Providencia rettgeri TaxID=587 RepID=C7FE03_PRORE ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKAMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00076319CD ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWKVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L060_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLVSHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium GAS191 TaxID=1882830 RepID=A0A1H5JPA0_9RHIZ ---KLAEEFARLEGKSGGRLGVAMLDTGTGMRA-GHRQEERFPMCSTFKLLAAAAVLDRVD -AGKESLDRRIRFEAADILSNAPITKDHIGGDMTIAELCAAAITLSDNTAANLLLASFGGP -AGLTAYVRKLGDSTTRLDRNEPSLNTAVPGDPRDTTTPSAMLSTLQALTLGQALSVSSRE -RLIGWLVANKTGDARLRAGLPKTWRVGDKTGAGAHGTTNDVAIAWPPGRAPLLICTYLTG -SSANDDGRNAILAAVALAIAAGf ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI0013755FF0 ---ALQRGIQQLEKNAGGRVGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BHI3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTSSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE46_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAA------- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI00141E3A4F ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNAAIAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A165TI35_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTSAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Bosea sp. CF476 TaxID=2135474 RepID=A0A318X3S3_9BRAD --eEVREALFALDRKHGGRLGVAILDSGSGRVV-AHRGEERFAMCSTFKFAAAAYVLARVD -RGEEELERRVSYSKADLITYSPVTEKHVDRGMTIAELCDAAVTLSDNAAGNLLLDSFGGP -KGLTAYMRALGDEASRLDRRELDLNEATPGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ -QLTAWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE -SRASFPEREAVLAEVGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTD7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRLDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G9FYZ9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIQGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q4JNX3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AKY5_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASXAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTF0_9BACT ---DVQQKLAELERQSGGRLGMALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000D782462 -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASIRALTLGDALPPAQRA -QLVAWMRGNQVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENGMAGAARIAVGTf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F749CFB ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALWPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI000993FFC5 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTISLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000B7ECB55 ---ALQRDIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE -SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARRDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas caseinilytica TaxID=438744 RepID=UPI0008492A6C ----LEAELASLEQRLDGRLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD -AGQEGLQRRVIYEQDDLVTYSPVTQEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFARSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQMLFLGDRLSKESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGEHGSTNNVAVAWPSDGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLVTR-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. STM 3843 TaxID=551947 RepID=H0TZ06_9BRAD ---EIDVTIAEIEAKSGGRLGVALLDTASGELT-GHRLDERFPMCSTFKVLAVAAVLARVD -AGQEQLGRRIPITQADLLSYAPVTKTHLDSGMTVAELCEAAITLSDNTAANLLLASFDGP -PALTRYLQSLGDSVTRVDRIEPDLNEATPGDPRDTTTPAAMAKTVAKLVTGSALSATSRE -MLIGWMIDCKTGAARLRAGLPSGWRIGDKTGSGSHGSANDVAVIWPQNRAPLIVTSYLTE -TDLSDEKRNAVHAEIGRIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ44_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -AGVTALARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000E233E68 ---ALQRGIQQLEKNTGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTQ2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRTMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. WT00C TaxID=1892903 RepID=UPI000949C822 --dALTARLSRLEADIAGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -QGQEQLTRRVVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP -AGLTRFVRTLGDELTRLDRNEPTLNEAVPDDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLTQWLIANQTGDKRVRAGLPASWKVGDKTGTGRLGTANDIGVVWTTQGAPLLFAVYLTE -NAATDAGRDAVHAEVGRLI---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Morganella morganii TaxID=582 RepID=I7ABV1_MORMO ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIV---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A345T8M3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASITAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. SOD TaxID=2495579 RepID=A0A430HLS1_9BURK ---EAQARLAALETAAGGRLGVDAIDTGDGRRL-GHRADQRFPMCSTFKAIAAAAILAHGK -NVPGWLDQRVRYGKADLVSYSPLTEKHVDAGMTIGELCAATIQYSDNAAANLLMKLIGGP -DGVTGFARSVGDTVFRLDRWETELNTAIPGDPRDTSTPAAMASLLRRVALDDGLPAAQRD -QLQNWMRGNTTGDTRIRAGVPAGWAVADKTGTGAYGSSNDIGIVFPPQGAPVVLALYYTQ -ADPQAKANSEILAAATKVVMAAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZC0_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVIWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=A0A2U1DHE1_PANAN ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000D7539B0 ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00061C5136 ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPAGWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAVARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2PT38_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEQTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=I1V556_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -TSVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Abditibacterium utsteinense TaxID=1960156 RepID=A0A2S8SXL9_9BACT -----KARLAKLEREFGGRLGVFAVNSANGERL-IYRADERFPVCSTFKVLLASAILKRSV -QVPGLLHQRIKYQPSQLVSYSPITEKHVAQGMTVAQLCAAALQYSDNTASNLLMKILGGP -RAVTAFARAIGDSEFRLDRWETALNTAIPGDLRDTSTPQAMGRSVQRLVAGNVLAPQHRA -QLQRWMQGNTTGDTRIKAGIPANWKIGDKTGTGDYGTANDIAVVWPPHHEPVILTIYTTQ -HQKEAKARNDVIASAAKVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCBAU 051011 TaxID=858422 RepID=UPI001374285C --qRLIDEIKRLESESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKALAAAAILARVD -AGKEQLTRRITFEASALVTYSPVTEKHVGGDMTLAEICEAAVTLSDNTAGNLLLSALGGP -PGLTAFARSLGDQITRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALVVGTALSAPSRE -QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITGYLTG -ATVPAAQQNAIWASVARAVS--- ->[subseq from] Class A beta-lactamase n=1 Tax=Ewingella americana TaxID=41202 RepID=A0A502G9Q0_9GAMM ---AIQQKLAALEKNSGGRLGVVLINTADNTRI-EYRGDERFPMCSTSKVMAASAILKQSE -TEKELLNQRVEIKKSDLVNYNPIAEKHLDTGMTLAELSAAALQYSDNTAMNKLIAQLGGP -VGVTKFARSIGDTTFRLDRTEPTLNTAIPGDKRDTTSPLAMATSLHNLTLGKALGEPQRA -QLVEWLKGNTTGAESIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENHPPLVVVTYFTQ -PHQNAKARKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000CF56AB1 ---ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQNLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=C3TTN7_BURPE ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFYSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGP -QTVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) TaxID=1301098 RepID=A0A024HKE1_PSEKB --kALEAQLAKLERGSGGRLGVAVLDTGSGKRF-GHRADERFPMCSTFKALLAAAVLARVD -AGKEDLARRIIYGREALVDYSPVAEKHVGEPLSVAELCKAAVTLSDNGAANLLLESLGGP -AGLTAWLRTTGDTVTRLDRNEPDLNEGTPGDPRDTTTPTAMLETLQHLLLGNVLKASSRD -QLKAWLLANQTGDARLRAGVPMDWKVGDKTGTGPTGTSNDIAILYPPGRAPLLVTAYLTR -ATVSPEQRDKVLAEVGRLAA--- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0006177D13 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLARSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPATMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. DHOD12 TaxID=2571746 RepID=A0A4V1EII3_9BURK ---TVQAELAKLEASSGGRLGLAAIDTGSGARL-LHRADERFAFCSTFKVIAASAILKRSE -NEPGLLERRVIYSTQDLVTYSPITKPNVASGMTVAELCAAAIDYSDNTAGNLLMKILGGP -QAVTAFARSIGNETFRLDRWETELNTAIPGDLRDTSTPASMAHSLQQLALGDALAPRQRE -QLQAWLRANTTGGKRIRAGVPADWQVGDKTGTGDYGTTNDIGVVWRPSGAPLVIAIYFTQ -PRQDASPRDDVLAAAARIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z1VNJ2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDRTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium GAS113 TaxID=1884352 RepID=A0A1H1K181_9RHIZ ---KLAEEFARLEGKSGGRLGVAVLDTGTGMRA-GHREEERFPMCSTFKLLAAAAVLDRVD -AGKESLDRRIRFEAADILSNAPITKDHIGGDMTIAELCAAAITLSDNTAANLLLASFGGP -GGLTAYVRKLGDSTTRLDRNEPSLNTAVPGDPRDTTTPSAMLSTLQALTLGQALSVSSRE -RLIGWLVANKTGDARLRAGLPKTWRVGDKTGAGAHGTTNDVAIAWPPGRTPLLICTYLTG -SSANDDGRNAILAAVALAVAAGf ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. TaxID=1882437 RepID=A0A350CRQ7_9BURK ---TVTADFAALEAGLDGELGVAAIDTATGRTI-GHRQDQRFPMCSTFKVVLAAAVLARAA -REPGLLDRRLPLPKSVFVDWSPITGKHVDGDMSVAQLCAATLQYSDNTAGNVLLREVGGP -AGLTRHARALGDEHFRLDRWETELNTATPGDERDTTTPLAMARTLRKLLLLDGLPPAGRN -TLRDWMLGNTTGAARIRAGVPAGWQVADKTGTGSYGSASDIAVVYPPGKAPIVLAIYTRQ -SEKNAKARNDIIAEAAQIAVS-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI001370E264 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKFDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Class A extended-spectrum beta-lactamase CTX-M-143 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A650A8E7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLSTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000F5405EC ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=C1J898_BURVI -----AATFAALERAAGGRLGVCAIDTASGRRA-QHRADERFPFCSTFKAMLGAAVLARSV -EHPGLLQQRVTYAQADLVNSSPVSGRHVDTGMTVAQLCEAAIQYSDNTAANLAMKLIGGP -AAVTAYARSIGDDTFRLDRWETALNTALPGDLRDTTTPAAMAASIRVLTLGDALPAAQRT -QLVAWMRGNKVGDKRIRAGVPAGSQVADKTGTGDYGTTNDAGVVWLPSRAPIVLTVYYTQ -ARADAKAKENVIAAAARIAVATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1Z261_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLTELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTW2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFATCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Duganella sacchari TaxID=551987 RepID=A0A1M7NTN5_9BURK -----TAQLALLEKESGGLLGVAALNTGDGRQL-LHRADERFPVCSTFKMMLSAAVLARDP ----ALLKKRIPYEKSDLVPHAPITSKHVGEGMTVAELCEATLQYSDNPAANLLMKQLGGP -AAVTAYARSIGDSEFRLERWETELNTAIPGDPRDTTTPEAMARSLQKLVLGDALPPTQRK -QLKDWMLGNTTGATRIRAGVPAGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ -PGKDDKSHPEIHGEVAKIVIEAf ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. Sh1 TaxID=2607285 RepID=A0A5A9EWB3_9PROT ---ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAVLKTVD -QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP -AGLTAFMRGIGDRTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ -TAEGFKQQDSIHAEVARTVA--- ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium sp. OV277 TaxID=1882772 RepID=A0A1H0PBH6_9RHIZ ---SLEAAFKDLEKATGTRLGVSAHDTGSGKRI-DYREKELFAMCSTFKFFAAAAILARVD -QKKEQLDRIVTYKKSDLVDYSPVTEKHVGEGMSLAAICEAAITYSDNSAGNLMLDALGGS -KGLTEYARSLGDTITRLDRRETELNEATPGDPRDTTTPAAMRENLEKTVLGTALSEQSRK -QLADWLIGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD -PKGTADSRNAIHQKVASLIAEH- ->[subseq from] Beta-lactamase n=1 Tax=Buttiauxella brennerae ATCC 51605 TaxID=1354251 RepID=A0A1B7IRG5_9ENTR ----IGKKLAELEKSTGGRLGVVLINTADNSQI-VYRGDERFPMCSTSKVMAASAILKQSE -TQTGLLNQRVEIKKSDLVNYNPITEKHLDGGMTIAELTDATLRYSDNTAMNKLIAQLGGP -DKVTQFARSIGDKTFRLDRTEPTLNTAIPGDERDTTTPAAMAKTLQNLTLDNALAEPQRK -QLVEWMKKNTTGGASIRAGLPTTWTVADKTGSGSYGTTNDIAVIWPENQPPLVLVTYFTQ -PQKEAKSRNDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ56_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKRVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDILASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F82FDF5 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQCSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=UPI001150273A ------DHLAALEGRFDARLGVYALDTGSGREL-AHRADERFAMCSTFKALAAAAVLDATP ---PEYLDHRVHYQQADLAAYSPVAERHVADGMTIRELCDAAVRFSDNTAGNLLLEELGGP -GGITAFARSLGDDVTRLDRTEPELNTAIPGDERDTTSPRAIAGCVDALVLGDRLDPADRA -LLTEWLVGNTTGAARIRAGVPQGWRVGDKTGTGDYATANDVGVVWPPDRAPIVLAILTSR -ATEDADVDEALLAEATRVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans TaxID=80842 RepID=UPI00030ED6FE ---AISARLARLEAGIGGRLGVSLVDTAGARQW-GYRADERFPMCSTFKWLAAAALLRRVD -EGREQLTRRIVYHQRDLIPYSPTTGKHVGGTLSLAQLCEAAVTLSDNTAANLMLASMGGP -AGMTAFVRTLGDALTRLDRNEPALNQAVPDDPRDTTTPAAMTADLQRLVLGDALTPASRA -QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTPQGKPLLFAVYLTE -NAADDARRDALHAEVGRLIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543DNQ8_9PSEU ------DHLAALEGRFDARLGVYALDTGSGREL-AHRADERFAMCSTFKALAAAAVLDATP ---PEYLDHRVHYQQADLAAYSPVAERHVADGMTIRELCDAAVRFSDNTAGNLLLEELGGP -GGITAFARSLGDDVTRLDRTEPELNTAIPGDERDTTSPRAIAGCVDALVLGDRLDPADRA -LLTEWLVGNTTGAARIRAGVPQGWRVGDKTGTGDYATANDVGVVWPPDRAPIVLAILTSR -ATEDADVDEALLAEATRVVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Halomonas elongata TaxID=2746 RepID=A0A1B8P6S8_HALEL ----LEAELASLEQRLDARLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD -AGQEELQRRVIYEQDDLVTYSPVTKEHVGEPMTLDSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFARSLGDDMTRLDRWETKLNEAIPGDPRDTTTPAAMAADLQALFLGDRLSEESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGAHGSTNNVAVAWPADGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=E0WC49_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGTGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSO5 TaxID=716760 RepID=A0A2U1YM52_9PROT --dALAAKMTELEARSGGRLGVAVLDSGNGKLH-GWRGDERFPMCSTFKFLLAAAVLKTVD -QGKDRLDRRIPVTKADLVPYAPFSETRLDGTPTVAELCEAALTLSDNVAANLLLPGIGNP -AGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGSYGSANDIAIVWPEGRAPLLVACYLTQ -TAEGFKQQDSIHAEVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT53_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRVDERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTF6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRLDVLASAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Aquamicrobium sp. LC103 TaxID=1120658 RepID=A0A4U6C258_9RHIZ ---ELADRLRDIETAAGGRLGVAILDTGNGVRV-EHRAHERFAMCSTFKFLAAACVLARVD -RGEEQLDRRVTFAKDDLVTWSPVTEKHAGDGMTMTQLCHAAVTVSDNTAGNLLLTSFGGP -AGLTAFARSLGDELTRLDRIEPGLNEATKGDPRDTTTPAAMLGNLDRTVLGDALSPASRD -RLGAWLRANTTGDKRLKAGLPAGWTIGDKTGTGGNGATNDVGVIWPPEHAPIIVSAYLAE -TTIAPEKREAALREVGRIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A2A7SFF6_BURGA ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNAILAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A0S1Z249_ENTCL ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARLLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L057_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTSNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Chitinimonas sp. R3-44 TaxID=2594795 RepID=A0A516SCU7_9MICO ---TAQAQLAQLELAFKGRIGFFAIDTGNGSSL-GYRADERFPMCSTFKMMLAAAILARST -QTDGLLKQRIQYGQHDLLPHSPITEQHLKDGMPVADLCAATVQYSDNGAANLLMKILGGP -AALTAFAQSIGDHTFRLDRWETELNTAIPGDGRDTTTPAAMGRSLQGLALGNALPPPQRE -QLQTWLLGNTTGATRIQAGVPAGWRVGDKTGTGSYGTANDIAVLWPAHRAPVVVTVFTTQ -KEQHAKARNDVIASAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=C0LRU8_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDETFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI00075D3F96 ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNATLAAVARIVTATf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia gladioli (strain BSR3) TaxID=999541 RepID=F2LLP9_BURGS ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNATLAAVARIVTATf ->[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. AU12 TaxID=1638161 RepID=UPI0007808677 --------TERIETRLGARLGVFALDTGSGRRW-EHRANERFPMCSTFKVVACGAVLARVD -AGAENLDRRIRFETSDLVPYSPETERHVGGDMTLRAICEAAMTQSDNTAANLILASLGGP -AAVTAYARSIGDQETRLDRIETALNEATPGDPRDTTTPAAMAGNLRALAFGDALSPTSRV -VLTGWMVANRTGGAKLRAGLPDGWRVGDKTGGGDHGTMNDVAVIWPAGGEPVIIAVYMTE -TAASFDDRNAGIAEIGRGL---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. PIC25 TaxID=1958773 RepID=A0A2A2ECJ8_9PSED --qDIERRLAGIEEGVGGRLGVALLDLGTGLRA-GWRQDERFPMCSTFKFLAAAAILARQD -QGLDSLGRRVKFTTANLVEYSPATGPRADGEMTLAELCEAAVTLSDNTAGNLMLNSLGGP -EGLTAFARSLGDEVTRLDRYETALNEALPGDPRDTTTPAAMLDDMRKLLLGSALSPASRE -RLLGWLVANKTGAARLRAGLPKDWRVGDKTGSGDRGTANDIAILWPPGREPVLVTVYLTG -SDTDMNRRNAAIAEVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A097KV69_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSVAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum seropedicae TaxID=964 RepID=A0A4R8NC96_HERSE ---ALTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -EGKEQLARRIVYRQQDLVPYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP -AGMTRFVRSLGDDLTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAALLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. RIT 412 TaxID=2202161 RepID=A0A329IUJ5_9PSED --tDLERQLAALERRHGGRLGVAMLDTGNQRLI-AHRADERFAMCSTFKALAAAYVLARVD -RGEEDLSRRVVYGPEQLVPYSPVTQKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP -QGLTDWLRRAGDPVTRLDRREPTLNENRPGDVRDTTTPLAMLRTLQTLALGEALSGASRD -QLIAWLVSNTTGDQKLRAGLPAGWRVGDKTGSGSNNASNDIAIVWPPNRPPLIVTVYYSG -STADAGQVNALMAEIGNYAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI00047FB2A9 --qRLSDEIKRLESESGGRLGVCVLDTATNTRH-DHRGDERFPMCSTFKMLAAAAILARVD -AGHEQLTRRITFDASALVVYSPITEKRVGGDMTLAEICEAAVTLSDNTAGNLLLASIGGP -PGLTAFARSLGDQVTRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALVLGTALSAASRE -QLTAWLIANKTGDTRLRAGLAKDWRVGDKTGTGARGTNNDVAVTWPPGKAPIVITAYLTG -STVSAAQQNAILASVARAVS--- ->[subseq from] Beta-lactamase n=1 Tax=Bosea sp. Tri-39 TaxID=1867714 RepID=A0A4Q1TXN4_9BRAD --eEVREALFALDRKHGGRLGVAILDSGTGRVI-AHRGEERFAMCSTFKFVAAAFVLARVD -RGEEELERRVSYSKADLVTYSPVTEKHVEKGLTVAEICEAAVTLSDNTAGNLLLDSFGGP -KGLTGYMRSLGDEASRLDRRELELNEATPGDPRDTTTPVAMASVLRQTVLGGALSPASRQ -QLTAWLVANKTGDKRLRAGTPKGWRIGDKTGTGNNNATNDVGVIWPPGRAPLVVTAYYAE -AQVSFAEREAVLAEVGRLAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL01_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAXKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum seropedicae (strain SmR1) TaxID=757424 RepID=D8J247_HERSS ---ALTARLSRLEADIGGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -QGQEQLTRRIVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP -AGLTRFVRTLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLTQWLIANQTGAKRVRAGLPASWKVGDKTGTGRLGTANDIGVVWTAQGAPLLFAVYLTE -NAATDAGRDAVHTEVGRLI---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTG5_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAGLSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. aSej3 TaxID=2605638 RepID=A0A5S4YXG9_9BRAD ----LEEELARIERDSLGRLGVAVLDTETGLET-GLRAGERFPMCSTFKCLASAAVLKRVD -RAELGLEQLIRFEAKDVVQYSPATKDRVAAGMTLAEICEAALTQSDNTAGNLLLRQIGGP -DGLTSFLRSLGDNVSRLDRWEVELNEALPDDPRDTTSPAAMLQNLHRLMVGDALSAASRQ -RLTDWMVANKTGDTRLRAGVPRGWRVADKTGAGDRGTTNDVGVFWPPGRKPVLVAAYLTG -SQGSPEKRNATIAEVGRLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTS9_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGGKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZY0_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFATCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A9XG17_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTESTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudoduganella danionis TaxID=1890295 RepID=A0A6A8VZ43_9BURK -----TALLARLESESGGRLGVFALNTADGQHV-QHRADERFPFCSTFKMMLAGAVLARGP ----ALLAQRIPYGSADLLPHSPITGKHVGRGMTVAALCAATIQYSDNAAANLLIARLGGV -AAVTAFARSIGDQAFRLDRLETELNTALPGDLRDTTTPAAMAESLNRLVLGNALTTAARK -QLKDWLLGNTTGDTRIRAGVPSGWLVADKTGTGDYGSTNDIGVIWPPGKEPIVLAVYFTQ -PGKDDKARNEVIAEATRIALAAf ->[subseq from] Beta-lactamase n=1 Tax=Bosea lupini TaxID=1036779 RepID=A0A1H7UUZ2_9BRAD ---KLREGLFALDRKHGGRLGVAILDSGNGRIV-AHRGEERFAMCSTFKFVAAACVLARVD -RGEEELERRVSYSKADLVTYSPVTEKHVEKGLTLAEICDAAVTLSDNTAGNLLLDSFGGP -KGLTAYMRSLGDDASRLDRREPDLNEARTGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ -QLTTWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE -ASAAFPEREAVLAEVGRLA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5MYM2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKSVTN-- ->[subseq from] PenI family class A extended-spectrum beta-lactamase n=1 Tax=Burkholderia pseudomallei TaxID=28450 RepID=UPI0006806B83 ---AAERQLRELESTFDGRLGFVALDTATGARI-AHRGDERFPFCSTSKMMLCAAVLACSA -GEPALLQRRIAYAKGDLIRYSPITEQHVGAGMSVAELCAATLQYSDNTAANLLIALLGGL -QAVTAYARSIGDATFRLDRREPELNTALPGDERDTTTPAAMAASVHRLLVGDALGAAQRA -QLNAWMLGNKTGDARIRAGVPADWRVADKTGTGDYGTANDIGVAYPPNRAPIVFIVYTTM -RNPNAQARDDVIASATRIAARAf ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. FBZP-16 TaxID=2065382 RepID=UPI000C31B657 ---KLREGLFALDRKHGGRLGVAILDSGNGRIV-AHRGEERFAMCSTFKFVAAACVLARVD -RGEEELERRVSYSKADLVTYSPVTEKHVKKGLTLAEICDAAVTLSDNTAGNLLLDSFGGP -KGLTAYMRSLGDDASRLDRREPDLNEARTGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ -QLTTWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE -ASAAFPEREAVLAEVGRLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=UPI000E6A04F8 --kRLAGAIAALEKRSGGRLGVAVLDTGTGQSF-GHRADERFAMCSTFKFLLAGAILKQVD -EGRERLDRRIPVSKADMVPYAPFVETRLDGPPTVVELCEATMTLSDNVAANLLLPAVGDP -AGLTAFLRTLGDRKTRLDRNEPSLNSAIPGDPRDTTTPAAMVHSMERLMLGDALTPASRE -QLIAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDIGIVWPEGRAPLLIASYLTE -TADGFKERDATHAGVARAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 7(2017) TaxID=1404411 RepID=UPI0014091DA5 ---RLQQEFARIELATSGRLGVAAHDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD -RDESSLDQRVQIEAKDILAYAPVTKEHVGSSMTLSELCEAAITLSDNTAANLLLREIGGP -AGLTSFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPVAMLKNLQRVAIGDVLQATSRQ -RLIDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZW1_9BACT ---DAQQKLAELERQSGGRLGVALINTADNSQI-LYRANERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLATWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A2R3SK36_PROMI ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L041_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTSDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia sp. DD3 TaxID=1410619 RepID=A0A083ZY90_9GAMM --qQAQQQLAALEKQHMGRLGVFAIDTTSSNTL-QLNAHQRFAFCSTFKVIAVAAILHHSL -SHPGFLDQRIHYQASDLVTYSPITEKHLDSGMTIAELCAAALQYSDNTAGNMLMKQLGGP -AAITAYARSLGDTTFRLDRWETELNSAIPGDERDTTTPAAMAASLQKLTLGTALPEAQRQ -QLVNWMKGNTTGNKRIRAGMPPDAVIADKTGGGDYGTTNDIGVVWLSGRAPWLVVIYFTQ -PNQHATANNEAVAAAARIISQAf ->[subseq from] Beta-lactamase n=3 Tax=Pantoea ananas TaxID=553 RepID=A0A0H3KVV5_PANAA ---ALQRGIQQLEKNAGGRLGVAVTDTTDGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. B40 TaxID=95608 RepID=UPI0003492979 ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKSNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P8NAU0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNIAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQA5_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKPDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILITYFTQ -PRPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. BJB480 TaxID=1871181 RepID=A0A3E1S8I8_9BURK ------ALLAKLEADSGGRLGVAAMNTADGRRL-LHRADERFPFCSTFKMMLAAAVLAK-- --GPALLKKRVRYSKADMVTYSPVTEKHIGRGMTVAALCEATIQTSDNTAANLLMKQIGGP -AAVTAFARSIGDMEFRLERMETELNTALPGDPRDTTTPASMVESLHKLVLGDGLGAAQRK -QLKDWMLGTTTGDTRIRAGVPAGSQVADKTGTGDYGTTNDIGVIWQPGKAPVALVVYLTQ -PGKDDKARSEIIAEAARIVVEAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQW2_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTAPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ85_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDCGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium GAS188 TaxID=1884351 RepID=A0A1H5FAC5_9RHIZ ---KLAEEFARLEGKSGGRLGVAMLDTGTGMRA-GHRQEERFPMCSTFKLLAAAAVLDRVD -AGKESLDRRIRFEAADILSNAPITKDHIGGDMTIAELCAAAITLSDNTAANLLLASFGGP -AGLTAYVRKLGDSTTRLDRNEPSLNTAVPGDPRDTTTPSAMLSTLQALTLGQALSVSSRE -RLIGWLVANKTGDARLRAGLPKTWRVGDKTGTGALGTTNDVAIAWPPGRAPLLICTYLTG -SSANDDGRNAILAAVALAIAAGf ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSA2s TaxID=709810 RepID=A0A4P7Z5E8_9PROT ---ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAVLKTVD -QGKDRLDRRIPVTKADLVPYAPFSETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP -AGLTTFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ -TAEGFKQQDSIHAEVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Skermanella pratensis TaxID=2233999 RepID=UPI0013015891 ---DLAGKLTEVERRLGARFGADILDTESGRRW-AHRAEERFPLCSTFKAIACGAVLAKVD -AGREDLERRIRFEAGDVVTYSPVTQDRVGGDMTLAEICEAAMTRSDNTAGNIILDSLGGP -AGVTEFARSLGDTVTRLDRWETDLNEATPGDPRDTTSPAAMVANLESLVLGDTLSRPSRD -RLTAWLVSNKTGDAKLRAGLPKDWRIGDKTGGGDHGTMNDVAVIWPPGRKPVIVSIYMTE -TKASFDDRNAAIAEIGRAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. FT127W TaxID=2660641 RepID=UPI00136A04F6 -------AFAALEKDLGGRLGVAAINLSNGKQA-GHRAGERFPLCSTFKAVLAAAILQRSA -SDPSLLQRRIHYTEKDLVPHAPITGERIAKGMTVEELCAATVQYSDNPAANLLMKVLGGP -EAVTAFARSVGDTEFRLDRWETELNTAIPGDPRDTTTPQAMMRSLQALVVGDALPAPQRQ -QLKEWLVGNTTGGKMIRAGTPAGWTVGDKTGGGAYGARNDIAVIWPPGKAPIVIAIYTAH -SQEDAKYREDIIAGATRAAI--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q6W8V9_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGSGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A023PZG3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDLRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Duganella TaxID=2636909 RepID=UPI0012B06126 --------LARLEKESGGRLGVAALNTADGRQL-AHRADERFPMCSTFKMMAAAAILSRDP ----SLLKKHIQYEKSDLVSHSPVTGKHVAEGMTVAELCEATLQYSDNAAANLLMKQLGGP -AAVTAYARSIGDNEFRLDRWETELNSALPGDARDTTTPLSMARSLQKLVLGDALPAPHRR -LLKDWMIGNTTGATRIRAGVPSGWTVADKTGAGDYGSVNDIAVLWPPGRAPIILAVYLTQ -PGKDDKLRPEIHGEVARVVIEAf ->[subseq from] UPI00144A4C37 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00144A4C37 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCXTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. AMG 501 TaxID=2008894 RepID=UPI000B5AB183 ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWAVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum huttiense TaxID=863372 RepID=A0A561KWY6_9BURK ---TLTATLSRLEADIGGRLGVSLVDTAGGRHW-GYRADERFPMCSTFKLLAAAAVLRRVD -EGKEQLERRIVYRQQDLVPYSPTTGKHTGGELSLAQLCEAAVTLSDNTAANLMLASMNGP -AGLTHYIRTLGDELTRLDRNEPTLNEATPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLTQWLVANQTGDKRVRAGLPKSWKVGDKTGTGRLGTANDVGVVWTDKGAPLLFAVYLTE -NAATDARRDTVHAEVGRLI---- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5MAF7_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDGTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Aurantimonas aggregata TaxID=2047720 RepID=UPI0013D83F87 ----FARRLAEIEDGLTARLGVAVLDTETGQRW-TRRGNERFPMCSTFKAVASGAVLARVD -AGEEDLGRRIVFAKSDLVPYSPGTENRVGGDMTLAELCEAAVTLSDNTAANLILASLGGP -SAVTAFARSLGDTATRLDRIEPDLNEATPGDPRDTTTPDGMVTSLAALTVDGSLSPASTR -QFADWMLANKTGDTRLRAGVPRDWRVGDKTGTGAYGTANDIAILYPPNRKPVIVSVYITE -TEATIDDRNAAIADVGRALA--- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum oryzae TaxID=286727 RepID=A0A5A9G1E5_9PROT ---ALAGKMTELEARSGGRLGVAVLDTANGKLH-GWRGDERFPMCSTFKFLLAAAILKTVD -QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGIGNP -AGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERILVGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVACYLTQ -TAEGFKQQDSIHAEVARTVA--- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. PAMC 28711 TaxID=1795631 RepID=A0A126ZLY4_9BURK ---DLKAALQRIEQASGGRLGVCMLDTASGRRI-GYRAAERFPMCSTFKLLAAARVLHRVD -AGQEELARAVTVARADIVPHSPLTEPHVGGTMTLGALCEATITQSDNAAANLMLASFGGP -TALTAYVRSLGDRTTRLDRNEPSLNEAIAGDPRDTTTPAAMLGLTRKLVLGDALKPASRE -QLRDWLLANKTGDRKLRAGLPAGWKVGDKTGGGAFGTNNDVGVVWPPNRPPVLVAAYLTQ -TAAALEQRDAALAAVAALI---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A2TK51_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas citronellolis TaxID=53408 RepID=UPI000718463C ---STLERLKRLERDSGGRLGVAVLDTGDGRRF-GLREDERFPLCSTFKLLLAACILARVD -RGEEQLARRIVYSQADLVEYSPASERHVGQPMSVAELCEAAITLSDNGAANLLLASLGGP -TGLTDWLRSTGDGVSRLDRNEPTLNQALPGDPRDTSTPRAMVATLQRLLLGDVLQAASRD -QLNAWLAANKTGDKRIRAGLPTGWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPVPAEKRDALLAEVGRLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoduganella sp. FT93W TaxID=2692177 RepID=UPI0013614818 -----AALLARLESDSGGRLGVFALNTADGQHV-QHRADERFPFCSTFKMMLAGAVLARGP ----ALLAQRVPYSNADLLPHSPVTGKHVGRGMTVAALCAATIQYSDNAAANLLIARLGGV -AAVTAFARSIGDQAFRLDRMETELNTALPGDLRDTTTPAAMAESLNRLVLGSALTTAARK -QLKDWLLGNTTGDTRIRAGVPGGWLVADKTGTGDYGSTNDIGVIWPPGQEPIVLAVYFTQ -PGKDDKARNEVIAEATRIALAAf ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000735ECBD ---ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE -SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARRDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00048A8C37 ---ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE -SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARRDVLAGAAKIVASGy ->[subseq from] Class A beta-lactamase n=3 Tax=Rahnella TaxID=34037 RepID=A0A5J6DYQ3_RAHAQ ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLTKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. SJZ115 TaxID=2572882 RepID=A0A560VI34_9BURK ---DAARQIAALESSFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=2 Tax=Yersiniaceae TaxID=1903411 RepID=A0A0H5LUL8_YERIN -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAAAALLKKSE -TQQALMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia massiliensis TaxID=419257 RepID=UPI00119D2E98 -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAAAALLKKSE -TQQALMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI00050F7284 ---DAARQIAALESGFGGRVGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8RMW4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTETTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Caballeronia sordidicola TaxID=196367 RepID=UPI0004D03980 ---SAEDQLKQLESNAGGRLGVAALNTADGKRV-DFRADERFPLCSTFKLVLVSAVLEQSA -LQKGLLDRRIHYTQSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLMKLVGGP -ETVTAFARSIGDNQFHLDRWEPELNTAIPGDPRDTSTPTAMAQSLQRVALGDALGASQRS -QLQTWLLGNTTGAGKIAAALPAHWMIGDKTGSGDYGTTNDIGVLWPPGKPPVVLTIYLTQ -REQDAKARNDVVASATRIVVGAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0F7VH92_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLVELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=A0A561FTU4_9BURK ----IARQLRQIEIRSGGRLGVAILDTLTGQSH-AYRGDERFPMCSTFKLLAAGLTLKRVD -QGQEQLARRIRYEAAELVPYSPITEKHVGGGMSMAELCEATLTLSDNTAANLLLHSFGGP -ARLTAYVRSLDDKVTRLDRIEPDLNQATPGDPRDTTSPVAMLSTMHQLLMGNALSADSRK -QLTTWLLANKTGDKRLRALLPAGWRVGDKTGSGAYGSTNDIGILFPPDRAPLLVASYLTA -TKASEAMRNAALAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia hierapolitana TaxID=1128676 RepID=A0A561T5F0_9PSEU ---AVADRLAELERRFDSRLGLYALDTGSGREL-AHRADERFAMCSVFKALAAAAVLHRTP ---PEYLDRRVHFSEADLIDPSPIAERHVAGGMTVRELCDAAVRYSDNAAGNLLLADVGGP -AGITEFARSLGDQVTRLDRTEPELNTAVPGDERDTTTPRAIAGTFRTLVLGDHLDPADRT -QFTEWLVGNRTGDERIRAGLPAGWRVGDKTGTGSYGTANDVAVVWPPDAAPIALAVLTSR -AAENATRDNALLAEAAAVVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB2FEE ---DLAGAFKAIEAEAGARLGVSAHDTGSDNRI-EYRQHERFAMCSTFKFLAAAAVLARVD -HEQERLERIVTYKKSDLVPYSPVTEKHVGKGMPLKAICEAAITMSDNTAGNLILDSLGGP -KGLTKYARSLGDATFRLDRRETELNEAKPGDDRDTITPSAILKDLQKTALGDALSKSSRD -QLTAWMLASKTGDKRLRAGLPKDWSVGDKTGTSDSGMANDIAVIWPPNRKPILLAVYLYD -PKGTADSRNDIHKKVAQLIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5B8WCP8_PSEAI --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDSTEPTLNTA-PGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=UPI000EACABD9 ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase n=17 Tax=Rahnella TaxID=34037 RepID=H8P0C7_RAHAQ ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase n=2 Tax=Saezia sanguinis TaxID=1965230 RepID=A0A433SCU1_9BURK ---DIQEQLAALERSAQGRLGVAALDMASGSTV-LYRSDERFAMCSTFKMVAVAAVLHYSM -HDDSLMAQQIVYEAADLVSYSPVTEKHAGSGMSVAQLCAAALQYSDNTAANLLVQLVGGP -QAVTAFARSVGDEVFRLDRWEPELNSAIPGDERDTTSPLAMMLSTRKLLLGDALGEAQRA -QLQDWMRGNAVGGQRIRAGVPPGWIVADKTGSGAYGVSNDVGVLWTPQQNPLVLAVFFTR -PVPDAKPDDAVVAQAARLVT--- ->[subseq from] Beta-lactamase OXY-1 n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A095FAQ8_BURGA ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=K7QZZ2_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZC4_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLVAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRLDVLASAAKIVTD-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Enterobacter sp. HMSC055A11 TaxID=1715020 RepID=UPI0008A63133 --nAIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. CF402 TaxID=1855289 RepID=A0A1H7PWU6_9BURK -------LLAGLEKEYGGRLGVAALNTADGRQV-LHRADERFPFCSTFKMMLSAAILSREP ----ALLKKRIKYHKSDLVSYSPVTSKHVADGMTVAELCEATLQISDNAAANLLMKQIGGP -AAVTAFARSIGDTEFRQERWETALNTALPGDVRDTTTPLAMAKSLQKLVLGEALPAAARK -QLKDWMLGNTTGATRIRAGVPAGWPVADKTGSGDYGTVNDIAVIWPPGKAPIVLAVYTTQ -PNKDDKTRPEIHGEAAKIVIEAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. RW407 TaxID=2202894 RepID=A0A2V2SWW6_9PSED ------ERLKQLERDSGGRLGVAVLDSGDGRRF-GLREDERFPLCSTFKLLLAAAVLARVD -RGEEQLARRIVYGRGDLVPYSPVSERHVGKPLSVAELCEAAITLSDNGAANLLLASLGGP -AGLTDWLRSTGDEVSRLDRNEPTLNEALPGDPRDTSTPRAMVATLQRLLLGDVLQPASRA -QLDAWLAANKTGDKRIRAGLPPLWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPASAEKREAVLAEVGRLA---- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=UPI00080825E6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=10 Tax=Bacteria TaxID=2 RepID=A0A127T7D6_9BACT ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU5_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase OXY-2 n=15 Tax=Bacteria TaxID=2 RepID=BLO2_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q30B66_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTESTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2H4H177_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDRTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Nitrobacter winogradskyi (strain ATCC 25391 / DSM 10237 / CIP 104748 / NCIMB 11846 / Nb-255) TaxID=323098 RepID=Q3SVS3_NITWN ----FVEELKRLENQTGGRLGVALLDAGTGQHV-GHRMDEPFPMCSTFKVLAAGALLQGVD -AGKEDLARRIYFNEADLVAHSPETRKHVGPTMTVAELCKAAITLSDNTAGNLLLASIGGP -QGLTAFARRLGDEVTRLDRIETELNESVPGDPRDTTTPSAMAANLRALALGDVLSVKSRT -QLVGWLVANTTGDKRLCAGLPAGWRAGDKTGTGERGTANDVAVIWPPDRAPFVVTAYLTG -ATVPADRQNAVMAAIGRAVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000BBD0B4C ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KT62_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPHDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAAIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTS2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAVNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAVAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000DC3834E ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDAHFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAINKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q5U8Y9_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLDRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=5 Tax=Enterobacteriaceae TaxID=543 RepID=B8XLJ7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLDRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Cellvibrio japonicus (strain Ueda107) TaxID=498211 RepID=B3PDF2_CELJU --tQLETPFQSLEQQHRGRLGIAALDTHTGKRI-AYRALECFAMCSTFKVILAGAILAQST -QQKGLLDKRIHYTAQDLVPYSPITEQHLHTGMTLGELCTASLQYSDNTAANLLMHQLGGP -QAVTAYARTLGDNDFQLERWETALNSAIPGDKRDTTTPQAMLHSLQQLTLGNALASQAQT -QLITWMKGNTTGNKRIRKALPQGWQAGDKTGSGDYGTSNDIAILFPPKRKPILLAIYFTQ -PTQDAPWNNDVIVEASRLVLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A1E3EFK2_BRAEL --qQLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP -AGLTGFFHTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVLGDVLQTVSRQ -KLVDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A4Q4JUJ3_BRAEL --qQLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP -AGLTGFFHTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVLGDVLQTVSRQ -KLVDWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A542BQU4_SERFO ---ATQQKLADLEKRSGGRLGVALINTADNSQI-HYRGNERFAMCSTSKVMAVSAVLKQSE -TQKNLLNRRVEIKKSDLVNYNPITEKHLDTGMTLAELSAATLQYSDNTAMNKLLSTLGGP -AKVTQFARSIGDVTFRLDRPEPELNTAIPGDERDTSSPLAMAKSLHNLTLGNALGEPQRA -QLIAWMKGNTTGAESIRAGLPATWVVGDKTGSGDYGTTNDIAIVWPENRAPLILVTYFTQ -PQQDAKGRKDVLAAATKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia cypriaca TaxID=882449 RepID=A0A543GFB9_9PSEU ------DRLAELEQRFDARLGVYAVDTGTGREL-AHRADERFAMCSVFKALAAAAVLHRTP ---PEYLDERVRFTQADLVDPSPVAAQHVADGMTIRELCDAAVRYSDNTAGNLLLADVGGP -PGITAFARSLGDQVSRLDRAEPELNTAIPGDERDTTTPRAIAGSFRALVLGDHLDPADRD -LFTQWLVGNTTGDERIRAGMPPGWRVGDKTGTGSYGTANDVAILWPPDGAPIALAVLTSR -AAEDATRDYALLAQAAAVVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ34_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIRPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013D3E6A7 --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-SYRANERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKIVTDGy ->[subseq from] Beta-lactamase n=17 Tax=Bacteria TaxID=2 RepID=D3INY1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520FUS7_9BURK -----ADSLAALETDTGGRLGVMALDTASGRQV-AHRAQERFALCSTFKVLAAAAVLRDGT ----ASLGQRVRYRREDLVTYSPVTGKHVTEGMTVGELCAAALQYSDNTAGNLLIDRLGGP -AAVTAYARSIGDASFRLDRRETELNTAIPGDPRDTGTPGSMARNLQRLLLGDALPPAGRA -QLEAWMRGNTTGATRIRAGVPGGWAVADKTGAGDYGVVNDIGIAWPPDRAPIVLAIYFTQ -ERKDAPMRSEVVATAARIAVN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0WRK7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKPIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] FONA family class A beta-lactamase n=1 Tax=unclassified Serratia TaxID=2647522 RepID=UPI00046AF204 --nTIQQQLADLEKSSGGRLGVALIDTADNSQI-LYRADERFAMCSTSKVMAVSALLKQSE -TDKNLLDRRMAIKQSDLVNYNPIAEKHLDTGMTLGEFSAATIQYSDNTAMNKILEHLGGP -AKVTTFARSIGDKTFRLDRTEPTLNTAIPGDERDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPAKWIVGDKTGSGDYGTTNDIAVIWPSNNAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTEGf ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RT60_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLILVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQF6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSGLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans M1 TaxID=1078773 RepID=A0A0U3LLP2_9BURK ---AISARLARLEADIGGRLGVSLVDTVGARQW-GYRADERFPMCSTFKWLAAAAVLRRVD -EGREQLTRRIVYHQRDLMPYSPTTGKHVDGTLSLAQLCEAAVTLSDNTAANLMLASMGGP -AGMTAFVRTLGDALTRLDRNEPTLNQAVPGDPRDTTTPAAMTADLQRLVLGDALTPTSRA -QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVAWTPQGKPLLFAVYLTE -NAADDARRDALHAEVGRLIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium soli TaxID=553447 RepID=UPI00124554D4 --eALRRRFAEIEARSGGRLGVGVLDLQTGLRA-GHRAEERFPLCSTFKLLAAAAVLARVD -AGRESLERRVTYNAADLVAYSPVTEPRVGEGMALEALCAAAITLSDNTAGNLLLSAIGGP -SGLTAYLRSLGDPVTRLDRTEPDLNEARPEDPRDTTTPGAMLDTLQRLLRGSALSDASRA -RLLGWLRDNKTGATRLRARLPADWRVGDKTGTGENGTANDVGLLAPPVGEPILVTAYLTG -STASSEARNAAIAEVAQAL---- ->[subseq from] Beta-lactamase n=1 Tax=[Pseudomonas] mesoacidophila TaxID=265293 RepID=A0A2A4FJL4_9BURK ------TSLAELERAVGGRLGVCALDTATGRRV-EHRAGERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTVRQTDPVGWSPVTKKHVGTSMTVGELCEATAQYSDNGAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWELELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPPGWQVGDKTGTGDYGTLNDIGVLWPPARGPIVLTVYYTQ -AHADAKRDDGVIVAATRIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4FF82_KLEOX ---AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Roseomonas genomospecies 6 TaxID=214106 RepID=UPI0011F2B2E3 --kRLDDAIAALETRSGGRLGVAVLDTGTGQRF-GRRADERFPMCSTFKFLLAGAILKRVD -EGRERLDRRIPVTKTDLVPYAPFAETRLDGPPTVAELCEATMTLSDNVAANLLLPAVDGP -AGLTAFLRTLGDTQTRLDRNEPSLNSAIPGDPRDTTTPTAMVHSMERLMLGDALTPASRG -QLVAWMVANRTGDKRLRAGLPKGWRVGDKTGTGVRGTANDVAIVWPEGRAPLLIASYLTE -TADGFKERDAIHAGVARAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000B60AC7C ---ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLIRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI0012F7C557 ---SAEAQLAALESSVGARLGVAALDTGSGARV-LHRATERFALCSTFKAMLAAAILARSA -RDGSLLERRVSYGKSDLLPNSPITEKNLGQGMTVSALCAATMQYSDNAAANLLMKILGGP -AAVTAFARSIGDQSFRLDRWETELNSAIPGDLRDTTTPEAMAASLQRLVLGDALGAAQRS -QLEAWLLGNTTGATRIRAGVPADWKVGDKTGLGSYGSNNDTGVLWPPAGAPVVLAVYLTF -PREDAPARNDVIASAARIVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=UPI000BABE246 --eAFERRLARIEDDIGGRLGVALLDLGTGLRA-GWRQDERFPMCSTFKFLAAAAILARQD -QGLDSLERRVKFAAADLVEYSPGTGPRADGEMTLAELCEAAVTLSDNTAGNLMLNSLGGP -EGLTAFARSLGDDITRLDRYETALNEALPGDPRDTTTPAAMLADMRELLLGTALSPASRE -RLLGWLVANKTGDARLRAGLPKDWRVGDKTGSGDRGTANDIAILWPPRREPMLVTVYLTG -SDADMNRRNAAIAEVGKLISD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=K7QSJ9_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGHLGGP -EKVTAFAHSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Collimonas fungivorans TaxID=158899 RepID=UPI0007786C8A ----VTRQLRQIEAKSGGRLGVAILDTASGQSH-AYRGDELFPMCSTFKLLAAGLTLHRVD -QAQEQLARRIRYETAELVPYSPATEKHAGGDMSVAELCEATLTLSDNTAANLLLHSFGGP -TQLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPSAMLSTMQQLLLGNALSADSRK -QLATWLLANKTGDKRLRALLPAGWRVADKTGSGAYGSTNDIGMLLPPGRAPLLVAAYLTG -TKASEATRNATLAEVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodoplanes serenus TaxID=200615 RepID=UPI0012D71CE1 --eTLAAAFARIERESGGRLGVAVRDTGAGLRA-GHREDERFPLCSTFKLVAAAAVLARVD -AGRERLDRRVAIPRDGLVTYSPVTERHAGEEMTLEALCEAAMVLSDNTAGNLLLEAIGGP -AGLTDFARSLGDPVTRLDRIEPFLNESAPGDPRDTTSPAAMLETVRRLALGDALAAGSRE -KLVAWMVGNRTGDARLRAGVPAGWRVGDKTGTGDRGTANDVGVIWPPGRPPVVVAVYLTE -TEAAPAVRNGAHAAVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTR7_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYGDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C0L620_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYGDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. T529 TaxID=2491343 RepID=A0A3P3ETY2_9BURK ---KAEAQLAALERSVGGRLGLVAFDTATGARV-QHRATERFPMCSTFKMMASAAILARSS -REPGLLERRVSYARSDILPNSPITEKHLGQGMTVSALCAATIQYSDNAAANLLMKILGGP -SAVTEFARSIGDPVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS -QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF -PTPDAQGRNDVIASAARIAAD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTL6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVIAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH219 TaxID=1074433 RepID=G3EPW0_9ENTR ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDRTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. ESBL53bB15_13_1E TaxID=1535134 RepID=A0A0A0R6B0_9ESCH ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAK------ ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0001C05D21 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTESTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q938A8_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4FPH5_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z1VNS7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDDVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A481S261_KLEVA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEHGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=J7II96_ENTCL ---SVEQKLAALEQRSGGRLGVALIDTADGSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SQHDLLNQRIEIKKGDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIAQLGGP -QGVTAFARKIGDETFRLDLTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDAQRA -QLVTWMKGNTTGTASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ -PQPEAESRRDVLASAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) TaxID=339670 RepID=Q0B7G1_BURCM -----ATSFAALEHAAGGHLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -ERPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPPAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -TRADAKPKDDVIAAAARIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. WS11 TaxID=1105204 RepID=A0A2P8KSB2_9BURK ----LARQLAEIEKKVGGRLGVHVLDTADGRRA-GHRQDERFALCSTFKFLAAALVLARVD -QGKERLDRRVTYARDDLVPYSPATEKHAGGEMTMAQLCEAAVTLSDNTAANLMLASFGGP -AGLTAYMRSLGDTHTRLDRIEPGLNEARAEDPRDTTTPAAIVDSMQKTLLGNALAPASRV -RLLQWLDDNKTGGQRIRAGLPADWKVGDKTGTGENGATNDIAILRPPGRAPVLLSVYLTE -TKSSMADRNAAHAAVAAAAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A3G3LGS6_BURGA ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKLVLVSAVLARAT -GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000D737A48 ---ALQRGIQQLEKNAGGRLGVAVNDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE -SANGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARRDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=A0A246WTY0_9BURK ---AFVNKMARLEADAGARLGVSIVNTGSGQAW-GYRADERFPMCSTFKFLAAAAVLKRVD -RGEERLERRIVYGKEILQEYSPTTAKHVGGDMSISQLCEAAMTLSDNTAANLMLDTMGGP -AGLTAFIRTLGDGETRLDRNEPTLNESIPGDPRDTTTPAAMTADLRRIVLGDALNPASRM -LITDWLVRNKTGDKRVRAGLPASWKVGDKTGTGDQGSTNTVGVIWPPTGAPLLFAVYLTE -TRASDTVRNGVHAAVGKLIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT92W TaxID=2666085 RepID=UPI0012AF1F4C ----PQDQLAALERSAGGRLGVAVLDTGSGKQV-LHRAGERFAFCSTFKTMVAAAILARGT -KEPDLLARRIHYTKADLVTYSPATEQHVADGMTVAALCEAAIQLSDNSAANLLMKILGGP -QAVTAYARAIGDQEFRLDRWETELNTAIPGDARDTTTPAAMMQSVNRLLLGDALGAPQRK -QLVDWMVGTVTGNERIRAGSPAGATVADKTGTGSYGVTNDIGVVWPKGKAPVVVVVYYTG -TDKDSKARSDVIASATRIAL--- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI00066522B9 ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RLU6_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI0003B214CE ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLIRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. AG702 TaxID=2183907 RepID=UPI000D71653F ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLIRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] Beta-lactamase n=31 Tax=Enterobacteriaceae TaxID=543 RepID=A0A4Q0DL01_ECOLX --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKIVTDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A345IT66_BURPY ------DALAALERSAGGRLGVCAIDIASGRRV-AHRQDERFPFCSTFKAMLSAAVLARSV -ERPALLQQRVTYTRADLVNYSPVSEQHVGEGMTVAALCEAAIQYSDNSAANLLMKLLGGP -PAVTAYARSIGDDTFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLMVGDALPAAQRA -QLVAWMRGNKVGDKRLRAGVPAGWTVGDKTGTGDYGTTNDAGVVWSPSGAPIALAVYYTQ -ARADAR----------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. SH223 TaxID=1074434 RepID=G3EPW1_9ENTR ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRAEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIV---- ->[subseq from] Beta-lactamase n=1 Tax=Hahella chejuensis (strain KCTC 2396) TaxID=349521 RepID=Q2SJQ2_HAHCH ---QLEKVFAKLEERLDARMGVMVLDTQTGRTW-GQRGQERFPLCSTFKVLACAALLAKVD -AGEENLERRVPIHARDIVTYSPVTKDRIGGEMTLRELCQAAMTKSDNTAANLVLKAVGGP -PRLTEYLRGLGDETTRLDRWETELNEATPGDPRDTTSPAAMASTLQTLFLNSPLSRASRQ -QLTAWFLANETGDAKLRAGLPQDWRIGDRTGGGAYGSTNDVAVIWPPGREPLIVTVYITE -TEAAFDDRNKAIADVGRAVGAAf ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. PH10 TaxID=1187851 RepID=J5PPT3_9RHOB ----LAETFAALEQQSGGRLGVALLDTRTGARA-GHRADERFPMCSTVKLLVTGATLAKVD -RGDDRLDRTIPVAESDLLAHAPVTRRHAGGDMTVEALCAAAMTVSDNTAANLLLDALGGP -AGATAFVRSLGDTVTRLDRKEPALNEALPGDPRDTTTPKAMLADLDALALGNALAPPSRE -KLVGWMVANETGGARLRAGVPDGWRVGDKTGAGGNGTSNDVAIFWPPGRPPVLVAVFLTG -SSAPPARRDEIIAAVGRAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium macuxiense TaxID=1755647 RepID=A0A109JNN0_9BRAD --qRLQEEFARIELATSGRLGVAVLDMETGLRA-SRRGDERFPMCSTFKVLASAAVLHRVD -RGESSLDQRVQFEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILREIGGP -AGLTSFFRTIGDNVSRLDRWEVALNEGVSGDPRDTTSPVAMLKSLQRVVLDDVLQAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPRRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVAA-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI000D701DFA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALWPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes elegans TaxID=29408 RepID=A0A327JY80_9RHIZ ---DLADDFARIERDSGGRLGVAVIDAATGART-GHRADERFAMCSTFKLLLAAAVLARVD -AGRETLDRRIPIDPAALLDWAPLTRPNAGGTMTVAALAEAAMVMSDNTAANLLLDTLGGP -LGLTAWLRLLGDPVTRLDRTEPTLNEALPGDPRDTTTPAAMAADIERLVLGDALSPASRD -TLTGWLVGNRTGAARLRAGLPKDFRVGDKTGTGERGATNDVGLFWPPERRPVIVAVYLTE -TTAPAAARDATIAAVAKAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I6SSC9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTLRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTP3_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRALLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KQ72_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT107W TaxID=2692168 RepID=UPI00136E9988 ------ALLAKLEADSGGRLGVAAMNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAK-- --GPALLKKHVRYSKADMVTYSPVTEKHIGRGMTVAALCEATIQTSDNTAANLLMKQIGGP -AAVTAFARSIGDMEFRLDRMETELNTALPGDPRDTTTPASMVESLHKLVLGDGLGAAQRK -QLKDWMLGNTTGDTRIRAGVPAGSQVADKTGTGDYGTTNDIGVIWQPGKAPVALVVYLTQ -PGKDDKARSEVIAEATRIVVEAf ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=UPI0009A235A8 ---AFVNKMARLEADAGARLGVSIVDTGSGQAW-GYRADERFPMCSTFKFLAAAAVLKRVD -RGEERLERRIVYGKEILQEYSPTTSKHIGGDMSISQLCEAAMTLSDNTAANLMLETMGGP -AGLTAFIRTLGDGETRLDRNEPTLNESIPGDPRDTTTPAAMTADLRRIVLGDALNPASRM -LITDWLVRNKTGDKRVRAGLPASWKVGDKTGTGDQGSTNTVGVIWPPTGAPLLFAVYLTE -TRASDTVRNGVHAAVGKLIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sphagni TaxID=1903179 RepID=A0A1S1WY95_9NEIS -----GARLARLEKDFGGRLGVFAIDTADGATL-GHRAGERFPFCSTFKAMLAGAILARSE -RQPQLLAQRIHYQKSGLVEYSPVTERHLEDGMTVAELCAATVQYSDNSAANLLLQLLGGP -AELTAYMRSIGDGSFRLERWEPELNGAIPGEERDTTTPQAMAQSLRQLALGDGLASPQRR -QLVDWLCGNTTGAEKIKAGVPADWLVGDKTGAGRYGSSNDIAVLWPQGRPPIVLAVYTTQ -PRRDAKPRHDVVASAARIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI000232305A ---ALQRGIQQLEKNAGGRLGVAVTDTADGTVF-TYRGDARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKADLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTCLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARKDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea ananas TaxID=553 RepID=UPI00051DEE3A ---ALQRGIQQLEKNAGGRLGVAVTDTADGAVF-TYRGEARFPLCSTSKVFAVAAILKKSE -SADGLMSEKIAIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNTAMNALLTRLGGP -QQVNAFARSIGDSTFRLDRKEPELNTAIPGDKRDTTSPDAMMQSLKKLVLGKALAPAQRQ -QLTDWMKGNTTGANSIRAGLPASWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDKHAAARRDVLAGAAKIVASGy ->[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT81W TaxID=2692166 RepID=UPI00136B1977 ------ALLAKLEADSGGRLGVAAMNTTDGRRL-LHRADERFPFCSTFKMMLSAAVLAK-- --GPALLKKRVRYSKADMVTYSPVTEKHIGQGMTVAALCEATIQTSDNTAANLLMKQIGGP -AAVTAFARSIGDMEFRLDRMETELNTALPGDPRDTTTPASMVESLHKLVLGDGLGTAQRK -QLKDWMLGNTTGDTRIRAGVPPGSQVADKTGTGDYGTTNDIGVIWQPGKAPVALVVYFTQ -PGKDDKARSEIIAEATKIVVEAf ->[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KQE6_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVPKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRT -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755CE41 -----DASLAALERDAGGRLGVCAIDAATGRRV-QHRADERFAFCSTFKAMLSAAVLARSI -ERPALLRERVTYRKADLVTYSPVTERHVGSGMTVAELCAATVQHSDNSAANLLMKLIGGP -QAVTAFARSIGDDMFRLDRWETDLNAAMPDDPRDTTTAGAMAASLRVLALGDALPLRQRA -QFVAWLRGNTTGDRRIRAGAPAGWPVGDKTGTGGYGTTNDIGVVWPPARGAIALAVFYTQ -ARADAKPNEHVIAEATRIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium embrapense TaxID=630921 RepID=UPI0009FD38A9 --qRLQDEFARIELATSGRLGVAALDMETGLRA-SLRGDERFPMCSTFKALASAAVLLRVD -RGESSLDQRVRFEAKDILANSPVTKDHVESGMTLAELCEAAITRSDNTAGNMILREIGGP -AGLTAFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVIGDVLQAASRQ -KLADWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase (Fragment) n=9 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0QZM8_9ESCH ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAK------ ->[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes roseus TaxID=29409 RepID=A0A327KWQ7_9RHIZ ----MAEAFARIERESGGLLGVAVIDTGSGARS-GHRADERFAMCSTFKLLAAAAVLARVD -AGKDALDRTIRIEETALVEYSPLTKPHVGGEMTLEALCEAAMVVSDNTAGNLLLESLDGP -AGFTAWVRTLGDAVTRLDRIEPHLNEAAPGDPRDTTTPAAMAANLQKLALGTMLPLPLRD -KLTGWLVGNRTGDTRLRAGVPRDWRVGDKTGTGERGSTNDVGILWPPNREPIVVAVYLTE -TTAAPEARNAVIAAVGKAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F031C9C ----AIQRLKQLETTFAGRLGVVALNTGNGEVL-SYRGDEPFPLCSTFKAMLAGAILQRSV -LTPGLLDERITYRKSDLVSYSPVSEKHVQDGMTVAELCAATVQYSDNSAANLLMKLLDGP -EGLTTFARSIGDHHFRLERWETELNSAIPGDLRDTTTPLAMAHSLQRLVVGDALPESQRQ -QLQTWLRGNTTGATRIRAGVPANWQVGDKTGTGDYGTTNDVAVLWPPGKAPVVLTLYLTQ -TSKDASPRNETLAAATRVVVD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0R787_9ESCH ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAK------ ->[subseq from] Beta-lactamase n=2 Tax=Noviherbaspirillum humi TaxID=1688639 RepID=A0A239JQV1_9BURK -------RLEELEKAFGGRLGLFALDTGSGASL-GYRDAERFPLCSTFKVMAAAALLRASE -RRPGLLAQRVHYRQSDLVEYSPLTEGHVDDGMTVAALCAAAIQYSDNTAANLLLQVLGGP -DEVTAFTRSIGDARFRLDRWETALNSAIPGDPRDTSTPAAMATSLQRLVLGEALAPAQRS -LLRDWLRGNTTGAARIQAALPARWIIGDKTGTGSYGTANDVAVLWPLRRAPIVLAIYSTH -PQEDAKGRSDIVAAAARIAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A1 TaxID=148446 RepID=UPI000469EAD3 ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFPLCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRRDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAHARSIGDATFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PDKGAKYDNATLAAVARIVTATf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0007DE1B65 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEANKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=E0WC50_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAATKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=W0FF77_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGHTHGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I4JT62_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTSSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia massiliensis TaxID=419257 RepID=UPI0011A775B0 -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAAAALLKKSK -TQQALMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLMLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007937AC6 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNLIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. WP5 TaxID=1500266 RepID=UPI0005617CD2 ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVSLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU3_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=[Erwinia] teleogrylli TaxID=1384589 RepID=UPI00073D4546 ----AQQQLQALESAAGGRLGVYAIDTASGKTV-AWRADERFPFCSTFKTIAASALLKRSE -SAPDFLNQRIHYSHSDIVNWSPVTEKHLSEGMTLAELSAAALQYSDNTAVNLMVDALGGI -DKVNEFARSIGDNTFRLDRRETELNSAIPGDERDTTTPAAMSHSLQKLALGNALGETQRS -QLVTWMKGNTTGARRIQAGVPSTWTVADKTGAGDYGTTNDIAVIWPEQGGPLVVSIYYTR -EQQNSPINNDIIAAATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M5JAJ8_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A2I4KG55_ENTCL ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTSSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSA6c TaxID=709813 RepID=A0A2U1WFA9_9PROT ---AFAARMTELEGRTGGRLGVAVLDSANGRLH-GWRGDERFPMCSTFKFLLAAAVLKTVD -QGKDRLDRRIPVTKADLVPYAPFSETRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGNP -AGLTAFLRGIGDKVTRLDRNEPALNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPESRK -QLTDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTH -TAKDFKQQDAIHADVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTU5_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRALLILVTYFTQ -PQPRAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus australis TaxID=286156 RepID=A0A1C0U8Q6_9GAMM ---SLHKQLAELENSAKGRLGVTLINTANGQAI-QYRGDERFPFCSTFKLIVVAAVLHKSM -SQSELLAKHISYSEADLLSYAPIARKHLKQGMSITQLCAATLQYSDNTAANLLIKELGGV -EAVNDFTQSLGDHTFRLDRWEPDLNSAIPDDPRDTTTPAAMATSVNKIVFGEVLAVSQRG -QLIDWLKGNTTGDASIRAGVPTGWVVGDKTGSGDYGTTNDVAILWPPKGAPVVLAVYFTQ -HQQDAESRRDVLASATRLVMEH- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=J7I3K6_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMGSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase CTX-M-5 n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=BLC5_SALTM --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYLADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKASDLVNYNPIAEKHVNGTMTLAELGAGALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKCWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14) TaxID=323097 RepID=Q1QR11_NITHX ----FVDELKRLETESGGRLGVTLLDTGTGQCV-GHRMDERFPLCSTFKVLASGAVLQGVD -AGKESLARRIYFNEADLVTHSPETHKRVGPIITVAELCKAAITLSDNTAGNLLLASIGGP -QGLTAFVRKLGDDVTRLDRIETELNEAAPGDPRDTTTPNAMASDLRALAVGDVLSAKSRA -QLVGWLAANTTGGKRLRAGLPAGWRVGDKTGTGERGTANDVAVIWPPDRAPFIITAYLTG -ATVSADRQNAVMAAVGRAVAT-- ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus daejeonensis TaxID=135193 RepID=UPI000373BDDC ----------NAAEEQGVRVSVNIQDLSGNQRL-SLGSTESYMPASTIKLALATALMQQVD -KGDLSLTDEVEVSPSDVVGGTGSLQKETPQQVTLERLARLMITQSDNTATNVLIDVV-GL -DTVQQLMDELGLTVMHLGRKMFAPAP--TPEQDNYIDASDLTTLLEEVYQGDVLSEASSE -QLITWMSEQEV-DTKFGSALP-QAPIAHKTGENAN-VTHDAGYFLVPGRE-LAISVLTQV -TTEAQAIGNPIVQRIAKAVYNY- ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus daejeonensis TaxID=135193 RepID=UPI000373BDDC -------------SERGIRVSVAIKDLSGSKEL-HLGSRQPYMPASTIKLALATALMQQVD -KGELSLSNEVEVSPSDVVGGTGSLQKETPQQVTLERLARLIITQSDNTATNVLIDVV-GL -DTVQQLMDELGLTVMHLGRKMFAPAP--TPEQDNYINAADLTTLLEEIYQGDVLSEASSE -QLITWMSEQEV-DTKFGSALP-QAPIAHKTGENAN-VTHDAGYFLVPGRE-LAISVLTEV -TTEAQAIGNPIVQDIARTVY--- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum seropedicae TaxID=964 RepID=A0A5B8E7R3_HERSE ---ALTARLSRLEADIGGRLGVSLLDTASGRHW-GYRADERFPMCSTFKFLAAAAVLRRVD -QGQEQLTRRIVYQKQDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMGGP -AGLTRFVRTLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLTQWLIANQTGAKRVRAGLPASWKVGDKTGTGRLGTANDIGVVGTAQGAPLLFAVYLTE -NAATDAGRDAVHAEVGRLI---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9E4L3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASVIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q5DUK0_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFAHSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=A0A4Q0RCQ9_9BRAD ------EAFEQLELKCAGRLGVSVLDTTTGAQI-HHRGDERFPMCSTFKVLAAAAILKGVG -SKLEGLERRVRIEQADLVEYSPVTSKHVGGDMSLRELCEAAITMSDNTAGNALLKNIGGP -AGLTSFARSLGDKTTRLDRIETELNEATPGDPRDTTTPNAMATNFRRLLLGDVLLTEGRD -QLGKWLIANKTGDSRLRAGVPKGWRVGDKTGAGEHGTTNDVAIVWPPERSPVIIAAYLTG -SALDPNGRNDVIASVGSAIAK-- ->[subseq from] Beta-lactamase n=2 Tax=Variovorax paradoxus TaxID=34073 RepID=T1XD52_VARPD ---SAEAQLAALERSVGGRLGLVAFDTATGARV-QHRATERFPMCSTFKMMASAAILARST -REPGLLERRVSYGRSDILSNSPITEKHLGQGMTVSALCAATIQYSDNAAANLLMKILGGP -SAVTAFARSIGDPVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS -QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF -PTPDAAGRNDVIASAARIAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum palustre TaxID=2044885 RepID=A0A2B8BEF0_9PROT ---AFAARMTELEGRTGGRLGVAVLDSANGRLQ-DWRGDERFPMCSTFKFLLAAAVLKTVD -QGKERLDRRIPVTKADLVPYAPFSETRLNGTPTVSELCEAAMTLSDNVAANLLLPGVGNP -AGLTAFLRGIGDKVTRLDRNEPSLNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPESRK -QLTDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTH -TAKDFKQQDAIHADVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1T3T0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYTDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Gha TaxID=1855318 RepID=A0A1I3J4I0_9BRAD -----VEAIKQLELKSGGRLGVSVLDTATGTPI-HHRGDERFPMCSTFKVLAAAAILKDVG -SKLEGLERRVRIEQADLVEYSPVTSKHVGGGMSLRELCEAAITMSDNTAGNALLKNIGGP -AGLTSFARSLGDQMTRLDRIETELNEAAPGDPRDTTTPNAMAANFSRLLLGDVLLPEGRE -QLGKWLIANKTGDTRLRAGLPRGWHVGDKTGAGEHGTTNDVAIVWPPERSPLVIAVYLTG -ASLDPNGRNDVIAAVGREV---- ->[subseq from] Beta-lactamase n=1 Tax=Chimaeribacter californicus TaxID=2060067 RepID=A0A2N5E243_9GAMM ---TLAAQLAELERSANGRLGVALIDTGSQREI-TYRGEERFAMASTFKVLAAGAVLQHSV -TQPDLLAKRIRYDRAALLSYAPVTGKHLAEGMTVAELCAAAIEWSDNTAANLLLTEIGGP -QRITKLARSLHDDKTRLDRWEPALNTAIPGDERDTSTPQAMARNLQHLALGDALPPAQQQ -QMIGWLKNSQTGAKSIRAGVPAGWEVGDKTGSGDYGTTNDLAIIWPPHGKPLVLAIYFTQ -PKADAEARRDVLATATRQVLAAf ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8733 TaxID=2609282 RepID=UPI00141ECFA8 ---DAQARLAALEAAAGGRLGVGALDTGDGRRL-GHRADERFPMCSTFKAIAAAAILAHGK -NVPGWLDQRVRYTKADLVTYSPITENHVDDGMTVGALCAATIQYSDNAAANLLMALIKGP -GGVTGFARSVGDTVFRLDRWETELNTAIPGDPRDTSTPAAMAALLRRVALDDGLPPAQRD -QLQNWMRGNTTGDTRIRAGVPAGWPVADKTGTGAYGSSNDIGIVFPPKGAPVVLALYYTQ -AYPQAKANSEILAAATRIVMGAf ->[subseq from] class A beta-lactamase n=1 Tax=Chelativorans sp. lm93 TaxID=2681485 RepID=UPI001358C063 --nQLRERIAALEKQSGGRLGLALLDTRSGTSI-AHRADERFAMCSTFKLLACAAVLARVD -AGKERLDRRIVYSKVDLVEWSPVTEKHADGSMALADICEAAMTLSDNTAGNLLLQSLGGP -AGLTAFARSLGDEVSRLDRYETALNDVSPGDPRDTTTPAAMLSNLRKIVLGTALSAPSRK -QITQWLLANKTGDRRLRAGLPSGWRVGDKTGTNRD-GANDIAIAWPPDRAPIVISAYLAE -MDVPMRERDAVIEKLGAIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9G4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLPNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAA------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1VVP0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTPPRAVAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000E2E41E2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVAYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002C5E13C ---ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A159ZLT4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDHVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. PDC64 TaxID=1881046 RepID=A0A1G6UC65_9BURK ---AAARALADLERRAGGRLGVAAWRRGGAQAI-AWRDDERFPFCSTAKVMVVATVLAQAS -RTPGLLDERVRYRKTDLVSWSPVTERHVDDGMTVADLCAAALQVSDNSACNLLLDRIGGP -AAVTAFARRVGDTAFRLDRRETDLNTAIPGDPRDTTTPRAMAKSLEALLLEQALAPEARR -RLLDWMLANTTGKERIQAGFPADWRVADKTGTGAYGTTNDVGIVFPPQGQPVIVAIYYTG -SSPDAQSDSKVAADAAAIVAR-- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4G457_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAATKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A345IT61_9BURK -----ATSFAALEHAAGGRLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -DRPGLLQQRVTYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -TRADAKPKDDVIAAAARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. DSM 18164 TaxID=1881058 RepID=A0A1I1LKN9_9BRAD --eEVRAALFALDRKHGGRLGVAILDSGNGRIV-AHRGEERFAMCSTFKFVAAAFALARVD -RGEEELERRVSYSKADLITYSPVTEKHVDKGLTVAEICDAAVTLSDNTAGNLLLDSFGGP -KGLTEYMRSLGDEASRLDRREPELNEARTGDPRDTTTPVAMAGVLRQTVLGAALSPASRQ -QVTAWLVANKTGDKRLRAGVPKGWRIGDKTGTGNNNATNDIGVIWPPGRAPLVVTAYYTE -SRSSFPEREAVLAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I8ANM0_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKTGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Aurantimonas sp. 22II-16-19i TaxID=1317114 RepID=A0A1X0T1M1_9RHIZ ---AITETIAAVEKRLGARVGAMIVDTQSGQTW-SHRAQERFPLNSTFKAFACAAVLAEVD -AGKAALDQHITFTADDLVTYSPVTEQRVETGMTLGEICDAAMTTSDNTAGNLVIESLGGP -DGVTRFMRQIGDAETRLDRTEPTLNEAAPGDLRDTTTPEAAATSLRELVLGDALSPRSRR -QLEAWLLGNKVGDPLLRAGLPKDWTIADRTGAGGHGSRSIVAIAWPPERKPVVAAIYLTG -TEASMEARSAAIAEIGTAIAR-- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A0C5C269_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000BF218AD ---DAARQIAALESSFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYMRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=B2CMB0_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DE02F34 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYCDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Citrobacter sedlakii TaxID=67826 RepID=Q93PQ0_9ENTR --qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE -THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP -GNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLRKLTLGDALAGPQRA -QLVDWLKGNTTGGQSIRAGLPAHWVVGDKTGAGDYGTTNDIAVIWPEDRAPLVLVTYFTQ -PQQDAKWRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZRE8_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAARIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRR-------------- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea allii TaxID=574096 RepID=A0A2V2BQP3_9GAMM ---ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE -TASGLLNENVTIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNAAMNKLLTRLGGP -QKVTRFARSIGDTTFRLDRTEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ -QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDPHAASRKAVLAGAAKIIASGy ->[subseq from] Beta-lactamase (Fragment) n=7 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0R7A2_9ESCH ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAK------ ->[subseq from] Beta-lactamase (Fragment) n=11 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A0A0R200_9ESCH ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAK------ ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. CCM 8734 TaxID=2609283 RepID=UPI00141EC5F7 ---EAQAELAALEAAAGGRLGVGAIDTGDARRL-GHRADERFPMCSTFKAIAAAAILAHGK -NVPGWLDQRVRYTKADLVTYSPITEQHLDDGMTVGELCAATIQYSDNAAANLLMAMIGGP -GGVTGFARSMGDTVFRLDRWETELNTAIPGDPRDTTTPAAMAALLRRVALDDGLPAAQRD -QLQNWMRGNTTGDTRIRAAVPASWAVADKTGTGAYGSSNDIGIVFRPKGGPVVLALYYTQ -ADAQAKANSDILAQATRIVMAAf ->[subseq from] Beta-lactamase n=2 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A0T9UJT5_YERFR -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILATYFTQ -PVKDAQNRREILAEAAKIAVSPf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M3R8A5_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAATKIVTE-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E83C7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVLYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. MC02 TaxID=2561931 RepID=A0A4Y9SIT0_9BURK -------ELAKLEAKAGGRLGVAAYEAGKAPRV-AHRADERFPMCSTFKTMAAGAVLKRSA -TDAGLLTRRVTYAKSDLVTYSPITEKHVAEGMTVAELCAAALQYSDNTAGNLLMQLVGGP -QGVTAFARSIGDEVFRLDRWETALNTAIPGDERDTTSPAAMARSYERLLLGDALPPAQRM -QLRDWMLGNTTGASRIRAGVPPEWKVADKTGTGDYGTTNDAGIAWPAADRALVMVIYFTQ -PSKGADAQSGVIAEAARLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Nitrobacter vulgaris TaxID=29421 RepID=A0A1V4I2E9_NITVU -heKFVDELKRLENESGGRLGVTLLDTSTGQRV-GQRMDERFPMCSTFKVLAAGAVLQGVD -AGKENLSRRIYFSETDLVTHSPETQKHVGPHMTVAELCKAAITLSDNTAGNLLLASIGGP -QGLTAFVRGLGDDMTRLDRAETALNEALPGDPRDTTTPNAMASDLRALVLDGMLSAESRA -QLAGWLAANTTGGKRLRAGLPAAWRVGDKTGSGERGTANDVAVIWPPDRAPFIVTAYLTG -ATASADRQNAVIAAVGRAVTTAf ->[subseq from] Beta-lactamase n=6 Tax=Yersinia enterocolitica TaxID=630 RepID=BLAC_YEREN ---SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASVTKIILS-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI000327E34D ---SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASVTKIILS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodospirillaceae bacterium SYSU D60006 TaxID=2268029 RepID=UPI000E65A649 --dELAAEFARIEREVAGRLGVAVLDTMSGEAA-GHRSDERFPLCSTFKLLAGAAILARVD -AGEESLERRIQFGAGDLVTYSPATEKRTGEPMTLAELCEAAITLSDNTAGNLLLETLAGP -AGFTAYARSLGDSATRLDRIEPALNEAIPGDARDTTTPAAMTANLNALILGDALSSASRN -RLTHWMIANKTGDARLRAGLPKDWRVGDKTGSGDRGTTNDIGVAWRPDQGPIIIAAYLTQ -TTAPTDQRNAALAAVARAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A515L5U7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTSSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DDDAED --pETLVKIKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase RAHN-2 n=2 Tax=Rahnella TaxID=34037 RepID=E3U909_9GAMM ---SVQQQLTALEKESGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLTRSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAKSRRDVLASAAKIVTP-- ->[subseq from] Class A beta-lactamase n=1 Tax=Massilia lutea TaxID=321985 RepID=A0A4V0Z2Y9_9BURK ----ADAGFAAIERDLKGRLGVAAIDTATGKIV-GNRLDERFPMCSTFKAILAAQALHRAA -REPGFLERRLRYARADLVSHSPVTGKHVDTGMTVAELCAATVQYSDNTAANTLMKELGGP -AGLTAFARGLGDEAFRLDRWELALNSAIPGDERDTTTPLAMARTLQKLVVGTALPAPQRQ -QLKDWLLGNTTGGNRLRAAVPAAWQVGDKTGTGTYGVTNDIGIVYPPGRAPLVVVVFTHR -DDKEADAREDVVADAARAAIR-- ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. SAP-35 TaxID=2703883 RepID=UPI00140B41B7 -----EARLARLEQASGGRLGVAAIHTGDGRVL-AHRGDERFPFCSTFKMMLAAAVLARDP ----ALLTKRIRYTKDDLVPHAPVTARHLDDGMTVAELCAATLQYSDNPAANLLMKQIGGP -AAVTAYARSIGDAEFRQERWETELNSAIPGDPRDTTTPAAMARSLHKLVLGDALPPPQRQ -QLKDWMLGNTTGATRIRAGVPAAWPLADKTGAGDYGTVNDIAVVWPPGAAPIVLAVYLTQ -PGKDDKIRPEFHGEVAKIVIEAf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas knackmussii TaxID=65741 RepID=UPI001362523F --kALEAQLAKLELDSGGRLGVAVLDTGTGQGF-GHRADERFPMCSTFKALLAAAVLARVD -AGKEDLARHIVYGREALVDYSPVAEKHVGEPLSVAELCKAAVTLSDNGAANLLLESLGGP -AGLTAWLRTTGDTVTRLDRNEPALNEGTPGDPRDTTTPTAMLETLQRLLLGDVLKLGSRD -QLKAWLLANQTGNARIRAGVPKDWKVGDKTGTGPTGTSNDIAILYPPGRSPILVTAYLTR -STASPQQQDKVLAEVGRLAAK-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KMX4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0008FD5C8B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRCIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=1 Tax=Massilia flava TaxID=871742 RepID=A0A562PGY1_9BURK --------LADIERDLHGRLGVCALDLGSGKTV-GHRQDERFPMCSSFKALLAAQALARAA -REPGFLDKRLRYAKADLVSYSPVTEKHVEQGMTVAELCTAVVQVSDNTAANTLMKELGGP -AALTAWVRGLGDPTFRLDRWETELNTAIPGDERDTTSPLAMARTLGKLVTGDALPAAQRE -QLKQWMIGTTTGDRRIRAAAPAGWTVGDKTGTGNYGVTNDIGFLLPPGRAPIVIVVYMHQ -PALEAKTREDIVAAATRAAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A345IT64_BURGA ---DAARQIAALESSFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVT--- ->[subseq from] Class A beta-lactamase Sed1 n=2 Tax=Citrobacter sedlakii TaxID=67826 RepID=UPI000181D192 --qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE -THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP -GNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLRKLTLGDALAGPQRA -QLVDWLKGNTTGGQSIRAGLPAHWVVGDKTGACDYGTTNDIAVIWPEDRAPLVLVTYFTQ -PQQDAKWRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q4TZY8_PROMI --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKGLLSQRVEIKPSDLVNYNPIAEKHVNGTMTFGELIAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter thiooxydans TaxID=416169 RepID=UPI000D387319 ----ASARLVALERRHGGRLGVAVLDTGSGRRI-GHRVDERFAMCSTFKLLAAAAVLARVD -RGVERLERRVVFDKDALVTYSPVTSHRVGAPMTMAELCHAAITMSDNTAGNLLLHSLGGP -AGWTAYARSLGDGVSRLDRIETELNEARPGDPRDTTTPAAMLANLHALLLGTALSDASRG -QLAGWLRANTTGDARLRAGVPAGWRVGDKTGSGNHAATNDVAIIWPPQRKPLLVAAYYAE -STADADARNVVLAEVGRIAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI0010FF0F93 -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQNRREILAEAAKIAVSPf ->[subseq from] Beta-lactamase CTX-M-6 n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=BLC6_SALTM --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYVADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIRASDLVNYNPIAEKHVNGTMTLAQLGAGALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWGVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q9LAC0_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=10 Tax=Enterobacteriaceae TaxID=543 RepID=G1CCP7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000A10048B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris TaxID=1076 RepID=A0A0D7EIM5_RHOPL ------AAMKRIEASSGGRLGVAVLDSASGARM-GYRDNEAFPMCSTFKVLAAGAVLTQVD -AGHARLSDRVRFTRDAVVTYSPITKDRIGGEMTLAELCDAAIRYSDNTAGNLLLGQIGGP -PGLTQFARTLGDPVTRLDRTETDLNEAGPGDPRDTTTPAAMLSNLKNLVLGSALSESSRD -QLVAWLKGNTTGGTRLRAGLPTDWVVGDKTGSGGRGSTNDIAVIWPAERKPIVVTAYLTG -TEAPAEQRNAALASVGRAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium zundukense TaxID=1867719 RepID=A0A2N9VQX4_9RHIZ ---DLAAAFKTLEEKTGARLGVSARDTGSDNRI-DYRENERFAMCSTFKFLAAAAVLARVD -QKQEQLERMILIKKSDLVTYSPVTEKYVGKGMSIEAICEAAVTLSDNTAGNLMLDTLGGP -KALTKYARSLGDATFRLDRWETELNEAKPGDPRDTITPAAILKDLQKTMLEDALSRSSRD -QLVEWMLGSKTGDKRLRAGLPKDWNVGDKTGTSDSGMANDLAVIWPPDRKPILLAVYLYD -PKGTADSRNEIHKKVASLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q5XLZ5_ECOLX --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKNVLSQKVEIKSSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKIVTDGy ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=B3GA03_MORMO --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKNVLSQKVEIKSSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAENRRDVLAAAAKIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI00039DA7E2 ---DAARQIAALESGFGERIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAA -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PDKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1B3ILG4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYTDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Kluyvera sp. PO2S7 TaxID=2705459 RepID=UPI001425C4B5 --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKIVTDGy ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. JS1663 TaxID=1851577 RepID=A0A244EEW4_9BURK ------GRLAEIEKASGGRLGVAVLDSGSGRLA-GHRQDERFPLCSTFKALAAALVLARVD -RGQETLERRVRYARDELVTYSPATEKHAGEDMTMAQLCEAAVTLSDNTAGNLMLASFGGP -AGLTAFMRSIGDAHTRLDRIETALNEARAGDARDTTTPAAMAANMQKILLGGVLSPASRA -QLMQWLDDNKTGDQRIRAGLPAGWRVGDKTGSGENGTANDVAILRPPGRAPVLLSVYLTA -TRAPMAERNATIAAVGAAAA--- ->[subseq from] Beta-lactamase n=2 Tax=Salmonella TaxID=590 RepID=Q6T5A3_SALTM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI00068022AA -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQNRREILAEAAKIAVSPf ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. Root351 TaxID=1736522 RepID=A0A0Q6WJS8_9BURK -------AFAALEKDLGGRLGVCAINLANGRQV-GHRTGERFPVCSTFKAMLAGAILQRSA -SDATLLNRRIGYTRQDLVPHAPITEKNLAQGMTVAELCAATVQYSDNPAANLLMKVLGGP -EAVTAFARSIGDTAFRLDRWETELNSAIPGDPRDTTTPLAMMRSLQALVVGDALPAPQRQ -QLKDWLVGNTTGGKLIRAGTPAGWTVGDKTGGGAYGARNDVAVIWPPGQAPIVIAVYTAH -NKEDAGYREDIIAGAASAAI--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium 62-17 TaxID=1895810 RepID=A0A1Q4BCJ7_9RHIZ ---QLTTQFRHIERDSKGRLGIFVLDTQRDRYV-GYRQGERFPMCSTFKLVLAAAVLKRAD -QGKEKLDRPIPVKASDIVPNSPGTEKKVGDSMTLAELCAATTTLSDNAAANLILATLGGP -KGMTAFARSIGDTAFRLDRIEPMMSNATPRDLRDTTTPQAMAETVQKLVLGDVLSEASRA -QLTAWLVGNKTGDTRLRAGVPGDWRVGDKTGAGGHGTTNDVGLFWAPQRKPIIVSVYLTG -SRATSDERNAAIAAVARAVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. OXWO6B1 TaxID=1835724 RepID=UPI0009EE1EA1 ---ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE -TASGLLNENVTIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNAAMNKLLTRLGGP -QKVTHFARSIGDTTFRLDRTEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ -QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDPHAASRKAVLAGAAKIIASGy ->[subseq from] Beta-lactamase n=2 Tax=Yersinia massiliensis TaxID=419257 RepID=A0A0T9RGU3_9GAMM -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI00067E5F04 -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI001432DFD0 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETSCLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes piscinae TaxID=444923 RepID=A0A3S4B147_9RHIZ --eTLAAAFARIERESGGRLGVAVRDTGSGLRA-GHREDERFPLCSTFKLVAAAAVLARVD -AGQERLDRRVAIPPRDLVTYSPVTERHAGEEMTLAALCEAAMVLSDNTAGNLLLEAIGGP -AGLTDFARSLGDPATRLDRIEPFLNESVPGDPRDTTTPAAMLETVRRLALGDALAAGSRE -KLVAWMVGNRTGDARLRAGVPEGWRVGDKTGTGDRGTANDVGVIWPPGRPPVVVAVYLTE -TEAAPAVRNGAHAAVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q6W8V8_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTESTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGSGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. Root351 TaxID=1736522 RepID=UPI0009E67E3B ------TAFAALEKDLGGRLGVCAINLANGRQV-GHRTGERFPVCSTFKAMLAGAILQRSA -SDATLLNRRIGYTRQDLVPHAPITEKNLAQGMTVAELCAATVQYSDNPAANLLMKVLGGP -EAVTAFARSIGDTAFRLDRWETELNSAIPGDPRDTTTPLAMMRSLQALVVGDALPAPQRQ -QLKDWLVGNTTGGKLIRAGTPAGWTVGDKTGGGAYGARNDVAVIWPPGQAPIVIAVYTAH -NKEDAGYREDIIAGAASAAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas abietaniphila TaxID=89065 RepID=UPI0007826B32 ---SIEQTLAELERRHGGRLGVAILDTGHQRLI-AHRGDERFAMCSTFKALAAAYVLARVD -RKEEDLSRMIVYGKEQLVPYSPLTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP -PALTAWLRSTGDQVTRLDRREPDLNENRAGDPQDTTTPIAMLQSLRTLILGDVLSGASRD -QLIAWLVSNTTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAVIWPPNRAPLIVTVYYTG -AKATGDQINALMADVGRLVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum chlorophenolicum TaxID=211589 RepID=UPI00067A826E -----VQKMAKLESGVGGRLGVSILDTAKGRQW-GYRADERFPMCSTFKFLATAAVLKRVD -QGEERLERRIVYTKKSLVPYSPTTGKHTGGNLSMSQLCEAAMTLSDNTAANLMLESLGGP -AGLTAFIRSLGDDMTRLDRNEPTLNESLPGDPRDTTTPAAMVADLRKIVLGNALNPASRT -LITQWLLDNQTGTKRVRAGLPKGWKVGDKTGTGSHGSTNTVGVAWTPQGVPLLFAVYLTE -TDADEAKRNGLHAAVGRLIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain MC40-6) TaxID=398577 RepID=B1YZ28_BURA4 -----ATSFAALEHAAGGRLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -DRPGLLQQRVSYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -TRADAKPKDDVIAAAARIAVA-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia sp. KBS0801 TaxID=1179675 RepID=UPI00110D3BED -----ATSFAALEHAAGGRLGVCAIDSASGRRA-QHRADERFPFCSTFKAMLGAAVLAHSV -DRPGLLQQRVSYGPSDLVNYSPVSGKHVGTGMTVAELCEAAIQYSDNSAANLAMKLIGGP -SAVTAYARSIGDDAFRLDRWETELNTALPGDPRDTTTPAAMAASMRVLTLGDALPSAQRA -QFVAWLRGNKVGDKRIRAGVPAGSQVGDKTGTGDYGTTNDAGVIWLPSRAPIVLAVYYTQ -TRADAKPKDDVIAAAARIAVA-- ->[subseq from] Beta-lactamase n=4 Tax=Morganellaceae TaxID=1903414 RepID=Q9R429_MORMO ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=12 Tax=Bacteria TaxID=2 RepID=Q9EYX1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2R3NWP2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A1YTM6_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C1BEC70 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000FA94ECB ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013314893 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. CG3 TaxID=1075768 RepID=UPI0004764BCE ------AQLAELEKTLGGRLGVFALDTGDGSQL-SHRAGERFAFCSTAKVMIASAILARSA -QVAGRLRQRVRYAKGELVNYSPITERHVGDGMTVAELCAAGIQYSDNTSANLLIKILGGP -AAVTAYARSIGDTTFRLDRLETELNSAIPGDPRDTTTPEAMGLSLRRVALGDALAPASRE -LLQDWLRGNTTGAKRIRAAVPADWQVGDKTGTGDYGTANDVGVVWRPNRAPVVVSIYTTH -AEKDAKASDEVIAAAARIVV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6AL57_KLEPN ---DVQQKLAELERQSGGRLGVALINTAXNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAXNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFXQ -PQPKAESRRDVLASAXKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium 2SD TaxID=2502200 RepID=UPI0010F6827A ---KVREALFALDRKHGGRLGVAILDSGNNRIV-AHRGEERFAMCSTFKFVAAACVLSRVD -RGEEELERRVSYSKDDLITYSPVTEKHVEKGLTVAELCDAAVTLSDNTAGNLLLDSFGGP -KGLTDYMRSLGDEASRLDRREPELNEARQGDPRDTTTPVAMAGVLRQTVLGGALSPASRQ -QLTAWLVANKTGDKRLRAGVPKGWRIGEKTGTGNNNATNDIGVIWPPGRAPLVVTAYYAE -ASVAFPEREAVLAEVGRLV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Neisseria gonorrhoeae TaxID=485 RepID=A0A0A0VDI5_NEIGO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPATMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQV9_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTAPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASGAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q6PP90_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. CF444 TaxID=1144319 RepID=J2LRH1_9BURK ----VVSQLAKLEASVGGRLGVDIVDSATQRRW-GYRADERFAMCSTFKFLACAAVLKRVD -AGQERLDRRIIYGNDVLVAYSPTTGKHAGGDLTLAQLCEAALTLSDNTAANLILQSLGGL -EPFNQFVKSLGDKQTRLDRFETELNTAIPGDSRDTTTPAAMSDNLQRILLGDVLSPASRE -QLIAWMRRNKTGDRRVRAGMQPGWTVGDKTGSGDYGTTNTIAIIWPPQGKPLLASIYLTR -TKAPEDRRNAVLAEVGKIIV--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7DA77F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus chibensis TaxID=59846 RepID=UPI000FDA9143 -----------AAEAHGVGVSVDIKDLSGHETI-ELGSQDAYYSASIIKLALIATLMQEVD -SGQHSLDEKLTVKPEDVVGGAGSLQKKFPQDVTIGRLAKLMIIQSDNTATNALIGLV-GF -DKVNAFIKSQGFTITHLGRKMMTPAKS--PAEDNYASAPEMLTLLDRIYNAEVVSAKSRD -QILEWMKAQEV-NTKFGAVLR-GKPIAHKTGELGY-VSHDVGYFLIPGR-EIAIAVLTKV -LKKAEEQGNPYVQRIAKATYNY- ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus chibensis TaxID=59846 RepID=UPI000FDA9143 -----------TAESKGIRVSVGIKDLSGGAEV-HLGSLQSYMPASTIKMALVSTLMQQVD -KGALTLDQKVTVKPDDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL -DKVQALMDQLGLQTMHLGRKMFAAA--PTPEQDNYIDAADLVTLLAKIYNHEFLSAQSSN -QIISWMKAQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDVGYFLVPGH-EIAISVMTEV -TTEAQAIGNPVVQSIAKAVYS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N5Y1_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=6 Tax=Enterobacteriaceae TaxID=543 RepID=A0A5X8L928_SALTM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9E9T4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N600_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=C4NV37_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter sp. 50677481 TaxID=1736699 RepID=A0A0V9JS97_9ENTR --qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE -THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP -GNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLRKLTLGDALAGPQRA -QLVDWLKGNTTGGQSIRAGLPARWVVGDKTGAGDYGTTNDIAVIWPEDRAPLVLVTYFTQ -PRQDAKWRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella sp. NCTC 9189 TaxID=2583577 RepID=A0A509C742_9ENTR -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N5Y6_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q2V899_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAEPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A378CM31_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. B21 TaxID=2607496 RepID=A0A5A9FAU2_9PROT ----LAERLAALEERTGGRLGVAVLDTGSGRLQ-GWRVDERFPMCSTFKFLLAAAVLKAVD -QGKERLDRRIPVTQADMVPYAPFAEKRLNGTPMVAELCEATMTLSDNVAANLLLPGVGDP -AGLTAFLRGFGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPDSRR -QLADWMIANKTGDKRLRAGVPAGWRVGDKTGTGTNGTANDIAILWPENRPPLLVASYLTQ -TAKDFKQHDSIHAEVARAVA--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007E5319C ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00061469B4 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Shigella flexneri 4c TaxID=1617964 RepID=A0A0C5PJE3_SHIFL ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Beijerinckia sp. 28-YEA-48 TaxID=1882748 RepID=A0A1H4WRC5_9RHIZ ---KLDAAFRQIERDSGGRLGVFVLDTQSGLHA-GCRQNERFPMCSTFKLVLAAAVLKRVD -QGKETLDRRIHIAATDIISNSPATEKHVGDTMTLAELCEATTTLSDNAAANLILATLGGP -QGMTAFARSIGDKVLRLDRFETAMSDARPGDKRDTTSPQVMTETIQKLVLGDVLSEASKT -QLIAWLVGNKTGDTRLRAGVPKDWRVGDKTGTGGYGTTNDIGLFWPPHRKPIIVSAYLTG -SKATSDERNATMAAVARAIAT-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0006CA6B0D ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F51B019 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0011196DCD ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI001072A181 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9ANM2_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM-94 ES-beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFEA ---ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. SRS16 TaxID=282217 RepID=UPI001316118E ---DLPAQLAEIERGSGGRLGVGVLDTATGQRA-GHREDERFPMCSTFKLLASALVLARVD -RHEERLERRVLFGARDLVDGSPITGQHVGGNMTMAELCEAAITRSDNTAGNMLLASFGGP -KAFTTYARSLGDTLTRLDRNETSLNEARPGDPRDTTTPAAMLGNLQKILVGDALSPSSRA -QLLRWLDANKTGDERMRARLPAGWKVGDKTGSGERGATNDIGILRPPGRAPILVTIYLTE -TEAPANARNATIASAGAAIA--- ->[subseq from] TEM family class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000FD807C4 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000E1CF3CC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=H9BJT1_SHISO ---ETLVKVKDAEDQLGARVGYIELDLNSGKIFeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000253B3F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQRDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9AFC8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTGGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A318G5R6_KLEOX --dAIQQKLADLEKSTGGRLGVALIDTSDNSQV-LYRGDERFAMCSTGKVMAAAAVLKQSE -ADNQVLNKRLEIKKSDLVIWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP -DKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGSALGEQQRA -QLVTWLKGNTTGGQSIRAGLPANWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter spathiphylli B39 TaxID=1163407 RepID=I4VWB8_9GAMM ---AVAAHLAALERQHGGRLGVAMLDTGSGQHV-GHRADERFLMCSTFKLLAAAAVLARVD -QGSEQLDRRITYGKDVLLEWAPETSRHVGAQMTVGELCQAAITVSDNTAANLLLTSLGGP -AAVTAFVRTLGDPLTRLDRIEPELNRTRPGDLRDTTTPAAMLADMQALLLGDALSPASRG -QLIEWLCGNTTGKQQLRAGLPAGWRIGDKTGSGAQQETNDIAIIWPPQRKPLLVTAYYTG -SAADKDGRHAVLAAVGRLAA--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001111FAFB ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Salmonella paratyphi A TaxID=54388 RepID=A0A5I3QY74_SALPT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas sp. CQN31 TaxID=2184016 RepID=A0A317F9S8_9PROT ---QLEAALREIEAARGGRLGVAVLDSASGEAA-GHRATERFPLTSTFKLLAAGAVLAQVD -AGRMRLDDRIRYRREEVVTYSPVTERHAGADMTVGQLCEATMTLSDNTAANLLLRGLGGP -AGLTAWLRGIGDDVTRLDRWETALNEARPGDPRDTTTPAAMLATMQRLTLGDVLSPGSRA -HLLAWLRANRTGGTRLRAGLPPRWQAGERTGTGPNGTSNDVGLVWPPSGAPLLVAAYLTE -GAADMATRDAALADVGASVAAAw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=O34176_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9A2K7_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASRVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=Q8GNP9_9ENTR --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKIVTD-- ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=E0AF28_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=3 Tax=Neisseria gonorrhoeae TaxID=485 RepID=UPI0007DD53FC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0C5BXY6_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1U9XRB9_SHISO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A286SCJ7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0004617675 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD7879 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase TEM n=320 Tax=root TaxID=1 RepID=BLAT_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DDCCF3 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2971A2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8JH98_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Neisseria gonorrhoeae TaxID=485 RepID=Q27W39_NEIGO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=N0D6W6_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A2J0QVT1_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010AB34B7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Proteus mirabilis TaxID=584 RepID=B9DR46_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNIGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C7C8381 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=L0GCN8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTV -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. F49 TaxID=1777131 RepID=A0A2R2IVY8_9NEIS ---SAAARLAALEADFGGRLGVCALDTASGAEL-GHRAGERFPFCSTFKAMLVGAVLARSA -KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKLLGGP -AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPNAQR -QLVEWLRGNTTGAEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPVVLTVFTTQ -TREDAKQRHQVVAAAARIAAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Collimonas pratensis TaxID=279113 RepID=UPI00143D0FB6 ------EQLRQIEAKSGGRLGVAIFDSHSGQTY-AYRGGERFPMCSTFKLLASAFVLKRVD -QGKEQLTRRIRYQKADLVPYSPVTEHHTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP -AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGGNLSGTSRQ -QLTDWLLANKTGDKRLRALLPSGWRVADKTGTGDQGTANDIGMLLSPDGAPLLVASYLTG -APGPAAARDAVHAQVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KSD2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCNAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002513C27 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A8DZJ3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAKTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=U3N8Z2_KLEPN ---ETLVKVKDAEDQLDARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum thiophilum TaxID=528244 RepID=A0A0F2KSK1_9PROT -----AGRMAALEKRGGGRLGVAVLDTGTGRRL-AWRGDERFPMCSTFKFLLAAAVLRTVD -RGTERLDRRIPVTKADLVPYAPFAETRLDGTPTVAELCEAALTLSDNVAANLLLPGVGNP -AGLTAFLRDLGDRKTRLDRNEPSLNTAIPGDPRDTTTPVAMTHSMERLLVGDALRPDTRR -QLTDWMIANKTGDKRIRAGLPAGWRVGDKTGTGRNGTANDIAILWPGNRPPVLVASYLTG -TAEGFKQHDAIHADVARAVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q56H91_ENTCL ---ETLVKVEDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI00080677F1 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Bacteria TaxID=2 RepID=UPI000E292EB1 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Halomonas elongata TaxID=2746 RepID=A0A329Q237_HALEL ----LEAELASLEQRLDARLGVAVTDTGSGRHW-GHREDERFPMTSTFKVLACAALLDRVD -AGQEELQRRVIYEQDDLVTYSPVTKEHVGEPMTLGSLCEAAMGYSDNSAANMVLKAIGGP -SAVTDFTRSLGDDMTRLDRWETKLNEATPGDPRDTTTPAAMAADLQALFLGDRLLEESRE -RLTDWFLGNRTGDARLRAGLPDDWRIGDRTGSGAHGSTNNVAVAWPADGEPVIISAYLTE -FEGDMDQRNAAIAEVGKLVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. S171 TaxID=1641860 RepID=UPI00131C51E8 ---AAEDQLKQLESSAGGRLGVAALNTADGKRV-NYRADERFPLCSTFKLMLVSAVLEQSA -LQQGLLERRIRYTQSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAGNLLMKLVGGP -ETVTAFARSIGDNQFHLDRWEPELNTAIPGDPRDTSTPAAMAQSLQRVTLGDALGASQRS -QLQTWLLGNTTGADKIAAALPAHWMIGNKTGLGDYGTTNDIGVLWPPGKPPVILTIYLTQ -RKPDAKARNDVVASAARIVVGAf ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=B0JD04_ECOLX ---DTLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A77_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075AA0EF -----ATSLAELERAAGGRLGVHALDTATGRRV-QHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVGELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLWPPARGPIVLTVYYTQ -ARAP------------------- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6UK85_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDNVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Massilia sp. Root418 TaxID=1736532 RepID=A0A0Q7F4U0_9BURK ------SAFASLEKDLGGRLGIAAINLATGKQV-GHRAGERFPVCSTFKAVLAGAILHRSV -SDPALLQRRISYTSKDMVPHAPITEKNIAQGMTVAELCAATVQYSDNPAANLLMKVLGGP -EAVTAYARSIGDTDFRLDRWETELNSAIPGDPRDTTTPLAMMRSLQALVVGDALPATQRQ -QLKDWLVGNTTGGKLIRAGTPAGWTVGDKTGGGAYGARNDIAVIWPPGQAPIVIAVYTAH -DSKDAKYREDIIAGATSAAI--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes piscinae TaxID=444923 RepID=A0A327K6Q8_9RHIZ --eTLAAAFARIERESGGRLGVAVRDTGAGLRA-GHREDERFPLCSTFKLVAAAAVLARVD -AGQERLDRRVAIPPRDLVTYSPVTERHAGEEMTLAALCEAAMVLSDNTAGNLLLEAIGGP -AGLTDFARSLGDPVTRLDRIEPFLNESAPGDPRDTTSPAAMLETVRRLALGDALAAGSRE -KLVAWMVGNRTGDARLRAGMPEGWRVGDKTGTGDRGTANDVGVIWPPGRPPVVVAVYLTE -TEAAPAVRNAAHAAVARAVVA-- ->[subseq from] Class A beta-lactamase n=5 Tax=unclassified Herbaspirillum TaxID=2624150 RepID=A0A5F0LKQ0_9BURK ---SLVARLAKLEASVAGRLGVEILDSGSGRRW-GYRADERFPMCSTFKFLAASAVLRRVD -TGAEQLDRRIVYGEDVLVNYSPTTGKHVGGDLSLAQLCEAAITLSDNTAANLMLRSLGGL -DAFNKFVRSLGDDTTRLDRFETELNTSIPGDPRDTTTPTAMTGNLQKILLGDALSAASRR -QITAWMLANKTGDRRVRAGMQPGWKVGDKTGSGDYGTTNTVAIIWPPQGAPLLASIYLTE -TKASEEQRNTVLAEVGKLIV--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. AM6 TaxID=2661553 RepID=A0A5K7Y3K3_9GAMM ------SAIQAIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD -EGQESLSRKVAIRPADLVTYSPITEHHTRDGLTLEALCHATITTSDNTAGNLILDALGGP -AALTAYLRRLNDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL -ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE -SEADLAARNAAIADVGRLLVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=UPI0013E0EA56 ---TIEEQLTTLEKNSQGRLGVALINTKDNSQV-TYRGDERFAMASTSKVMAVAAVLKESE -KQSGLLDNPITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQNAKYRKDIIAKAAEIVTKEf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SK35_9BACT ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAICSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum oryzae TaxID=286727 RepID=A0A1X7EGH9_9PROT --dALAAKMTELEARSGGRLGVAVLDSGNGTLH-DWRGNERFPMCSTFKFLLAAAVLKTVD -QGKDRLDRRIPVTKADLVPYAPFAETRLNGTPTVAELCEAAVTLSDNVAANLLLPGIGNP -VGLTAFMRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMQRLMLGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAIVWPEGRAPLLVASYLTQ -TAEGFKQQDSIHAEVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum thiophilum TaxID=528244 RepID=UPI0006987310 -----AGRMAALEKRGGGRLGVAVLDTGTGRRL-AWRGDERFPMCSTFKFLLAAAVLRTVD -RGTERLDRRIPVTKADLVPYAPFAETRLDGTPTVAELCEAALTLSDNVAANLLLPGVGNP -AGLTAFLRDLGDRKTRLDRNEPSLNTAIPGDPRDTTTPVAMTHSMERLLVGDALRPDTRR -QLTDWMIANKTGDKRIRAGLPAGWRVGDKTGTGRNGTANDIAILWPGNRPPVLVASYLTG -TAEGFKQHDAIHADVARAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6PP91_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=D2D0D5_RAOTE -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase TEM n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A6D1S5A6_RAOTE -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase class A/beta-lactamase class A CTX-M n=2 Tax=Serratia fonticola TaxID=47917 RepID=A0A0U4IW52_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A126E3J8_ECOLX ---ETLVKVKDAEDRLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGREQLGRRIHYSQSDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT135W TaxID=2692175 RepID=UPI00136E3978 --------LARLEKESAGRLGVAALNTADGRTV-LHRADERFPFCSTFKMMLSAAILSREP ----ALLKKRIAYDKSDLVSYSPVTSKHVGEGMTVAELCEATLQISDNAAANLLMKQIGGP -AAVTAYARSIGDTEYRQERWETELNTALPGDPRDTTTPLAMAKSLQKLVLGEALPTAARK -QLKDWMLGNTTGATRIRSGVPAGWPVADKTGSGDYGSVNDIAVIWPPGKAPIVLAVYITQ -PNKDDKTRPEIHGDVAKIVIEAf ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C810935 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTNPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=5 Tax=Enterobacterales TaxID=91347 RepID=D9U8W0_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Hyphomicrobium sp. xq TaxID=2665159 RepID=UPI0012B957CE ---DLNARLAEIEAAAQGRLGVAILDTKTGELF-GRREFERFPLCSTFKVLAAALVLQRVD -SGEEKLDRRVVFSANDVVEYSPVTKDRAGAEMTMAELCTAAITQSDNTAGNLMLASFGGP -EALTQWLRTLGDAATRLDRTEPALNEVPPGDPRDGTTPRAMAYTLQRILLGNVLSKSSEK -LLIGWLTANTTGGARLRAGLPADWRVGDKTGTGARGATNDVAIVWPPDHPPIVIAVYLAD -TEAPIDVRNAAIADVGRATAALf ->[subseq from] Beta-lactamase n=1 Tax=Hahella sp. KA22 TaxID=1628392 RepID=A0A3T0VK73_9GAMM ---QLEKVFAKLEDRLGARMGVMVLDTQTGRTW-EQRGQERFPLCSTFKVLACAALLAKVD -AGEENLTRRVQIQARDIVTYSPVTKDRIGGEMTLGELCHAAMTKSDNTAANLVLKAVGGP -PKLTEYLRGLGDEITRLDRWETELNEATPGDPRDTTSPAAMASTLRKLFLDSPLSPASRQ -QLTNWFLANETGDAKLRAGLPQDWRIGDRTGGGAYGSTNDVAVIWPTGREPLIVAVYITE -TEAAFDDRNKTIADVGRAVGAAf ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. CFA14(1/10) TaxID=2511203 RepID=UPI001021A918 ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRHVSIKKSDLVNYNPITEKHLGKGMTIGELAAAALQYSDNTAMNKLIGQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVALGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLILITYFTQ -PEKNAKSRRDVLASAAKIVTQGy ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. UNPA324 TaxID=1141174 RepID=UPI0011514958 ----LFDAVQQLEIKSGGRLGVAVLDTKTGASV-HHKGDERFPMCSTFKVLASAAILKGAG -DKLDQLDRRIRIEQADIVENSPVTREHVGPDMSLRELCEAAMTRSDNTAGNLLLKNMGGT -AGLTAFARSLGDNVTRLDRTETELNEAAPGDPRDTTTPNAMAENFRRLLFGNELMPESRD -QLAKWLIANKTGDKRLRAGLPQNWRVGDKTGAGEYGTTNDVAVVWPPLRSPLIIAVYLTG -ASLDMNGQNEVIASAGREVAREf ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1P8SN36_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli 909945-2 TaxID=1269007 RepID=V0AKS9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPKERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM-94 ES-beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002C5E125 ---ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001033EE7C ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASVGCGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A142EC40_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DCF92F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPDDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=8 Tax=root TaxID=1 RepID=Q0H0C0_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. meg3 TaxID=2025949 RepID=A0A223P8F3_9BURK ----IVSQLAKLEASVGGRLGVDIIDSATQRRW-GYRADERFPMCSTFKFLASAAVLKRVD -AGQEQLDRRIIYGNDVLVSYSPTTSKHVGGDLTLGQLCEAALTLSDNTAANLILKSLGGL -EPFNKFIKSLGDKQTRLDRFETELNTAIPGDPRDTTTPAAMSDNLQHVLLGDVLSPSSRA -QLIAWMRSNKTGDRRVRAGMQHGWTVGDKTGSGDYGTTNTIAIIWPPQGKPLLASIYLTR -TKAPEDQRNAVLAEVGKIIV--- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=O32372_CAPOC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus cinerea TaxID=471575 RepID=UPI00140E7205 ---SLHKQLAELENSAKGRLGVTLINTANGQAI-QYRGDERFPFCSTFKLIVVAAVLHKSM -SQSELLAKHISYSEADLLSYAPIARKHLNQGMSITQLCAATLQYSDNTAANLLIKEVGGL -EAVNHFTQSLGDHTFRLDRLEPDLNSAIPDDPRDTTTPAAMAASVNKIVFGEVLAALQRE -QLIDWLKGNTTGDASIRAGVPTGWVVGDKTGSGDYGTTNDVAILWPPKGAPVVLAVYFTQ -HQQDAESRRDVLASATRLVMEH- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8KMX3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTG1_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVVMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRLDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=H9BJT2_SHISO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKSSHIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E085B7 --eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIRELGGI -AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE -QLAIWLKGNTTGGETIRAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ -REKDAKARRDVLAEATKMVLSH- ->[subseq from] Beta-lactamase n=8 Tax=Bacteria TaxID=2 RepID=D3KDJ9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q6UVM7_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGTSLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Cupriavidus pinatubonensis TaxID=248026 RepID=UPI0011286AEC ---DAESRLAALERSAGGRLGVFARHTGDGRQV-RHRAEERFPFCSTFKVILAGAVLQRSA -GAPGLLDEHVRYTRQDLVAYSPITEKRVADGMTIAQLCAAAIQYSDNGAANLLMHRLGGP -AAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRN -QLQAWLRGNTTGAARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQ -AAPDAKWSNETIASAARIAL--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000D318E9D ---ETLVKVKDAEDELGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium aquaticum TaxID=270351 RepID=A0A0J6S105_9RHIZ ---DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADELFPLCSTFKALAAAAVLARAD -KGQDDLNRRITYTRDALLSYAPVTGKHVETGMTLAELCAAAVVWSDNTAANLMLDRLGGP -AGITAFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDTILLGQVLSAESRA -RLTGWMQESPTGLKRLRAGLPEGWRTADKTGTGDNGTANVVALIRRPDGAPILAAVYLTG -SPAEPAARDALHAEIGRLIARSf ->[subseq from] Beta-lactamase FONA-3 n=2 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR1_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=UPI0007DCD4B8 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTIRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia sp. 3ACOL1 TaxID=2448483 RepID=A0A3G2FEH8_9GAMM ---NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Cobetia amphilecti TaxID=1055104 RepID=UPI000A079ACA ------SAIQAIESEVGARIGVTVLDTADGTRF-SWRGDERFPMSSTFKVLACGHMLSRVD -EGQESLSRKVEIRPADLVTYSPITENHTRDGLTLEALCHATITTSDNTAGNLILDTLGGP -AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL -ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE -SEAELAARNAAIADVGRLLVK-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002510F41 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella victoriana TaxID=1510570 RepID=UPI00103BBDCD ---SVQQQLAALEKDSGGRLGVMLINTADNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLTRRISLKKSDLVNYNPITEKHLDTGMTIGELAAAALQYSDNTAMNKLIEQLGGP -QKVTAYARTLGDSTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGTALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAKSRRDVLASAAKIVMQGy ->[subseq from] Beta-lactamase class A n=2 Tax=Rahnella aquatilis TaxID=34038 RepID=H2J1V6_RAHAC ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRHVSLKKSDLVNYNPITEKHLNTGMTVGELAAAALQYSDNTAMNKLIGQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVALGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase n=1 Tax=Yersinia nurmii TaxID=685706 RepID=A0A0T9L3L6_9GAMM --qSLSEQLAALEEKAQGRLGVSLINTQSGKEL-QYRGNEAFPFCSTFKLVLAAAILRQSM -SQPALLEKHITYSEADLLSYAPIARENLGKGMTVAALCAAALQYSDNTAANLLIQQLGGL -EGVNKFTQSLGDTAFRLDRWEPELNSAIPGDPRDTTTPSSMAALVKKIQFGDGLAPAQQQ -QLAQWLKGNTTGNASIRAGVPAGWVVGDKTGSGDYGTTNDVAILWPPTGAPLILAVYFTQ -HKKDAESRRDVLAEATRIILAEy ->[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI0013776F39 ---NIEQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTIWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTEGf ->[subseq from] Beta-lactamase n=1 Tax=Providencia stuartii TaxID=588 RepID=A0A2S1T433_PROST --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKGLLSQRVEIKPSDLINYSPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DD737D ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFFHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A5B8KR36_PROST ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9AGJ5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia lacunae TaxID=2211104 RepID=A0A370NB37_9BURK ---RIRQQLAQIEAETGGRLGVAILDTASGLHA-GLRMDERFPMCSTFKLLAAAAMLARTD -RGQEDLQRRILFSKADLLPNSPVTGEHTRERMSVADLCNAAITRSDNTAANLLLASFGGP -AGLTAFARSVGDSVTRLDRIEPTLNEAIPGDPRDTTTPNAMLGNLRELLLGERLSASSRE -QLKAWLVANQTGDERIRAKLPKDWRVGDKTGTGDRGTANDVAILWPPGRAPILVSVYLTE -TSGNAKRNNAAIAKVGALV---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9EIA5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLMRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMAERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=UPI0007DD5517 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSTLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G8A3R7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATTEERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0002F6E49C ---SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAARMNKLVLGDALRPAQRS -QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASVTKIILS-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea allii TaxID=574096 RepID=UPI000BB44634 ---ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE -TASGLLNENVAIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNAAMNKLLTRLGGP -QKVTRFARSIGDTTFRLDRTEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ -QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDPHAASRKEVLAGAAKIIASGy ->[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI001415429B ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLGTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVT--- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E83CC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DCE91F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTMIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI0004217104 ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase FONA-6 n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIQ6_SERFO ---NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A448SRU8_SERFO ---NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Uppsala TaxID=2565143 RepID=A0A5I6H430_SALET ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKILLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=UPI000E069F69 ---TIEEQLTTLEKNSQGRLGVALINTKDNSQV-TYRGDERFAMASTSKVMAVAAVLKESE -KQSGLLDNHITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQNAKYRKDIIAKAAEIVTKEf ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B4E8387 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSCLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEICASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=A0A0A1FDD8_9BURK ----IVAQLRQIESTTGGRLGVAIFDSRSGKTY-AYRGDERFPMCSTFKLLASALVLKRVD -QGKEQLARRIRYKASDLVPYSPATEHHTGGDMSVGELCEAAITLSDNTAANLLLQSFGGP -AQLTAYMRASGDKMTRLDRIEPHLNESAPGDPRDTTTPNAMVHSLREILLGDNLSASSRQ -QLTDWLLANKTGDKRLRALLPAGWHVADKTGTGDQGTANDIGMLLPPGGAPLLVASYLTG -TKASAAARDAVHAEVGRLAA--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0009E3695C ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ70_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAVKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESCLDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. SJZ147 TaxID=2572896 RepID=UPI0011AAECE8 ---ALQRDIQQLEQTAGGRLGVAVTDTADGAVF-TYRGNTRFPLCSTSKVFAVAAILKKSE -TASGLLNENVAIHKTDLVNYNPITEKHVGATMTVAELSAAALQYSDNVAMNKLLTRLGGP -KKVTRFARSIGDTTFRLDRKEPDLNTAIPGDKRDTTSPAAMMQSLQKLVLGSALAPAQRQ -QLSDWMKGNTTGANSLRAGLPADWTVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -PDPHAASRKAVLAGAAKIIASGy ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0006822DC1 -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDTLAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI0011D2A648 -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDVRDTTTPQAMANTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. NFACC02 TaxID=1566250 RepID=A0A1H9MK48_9PSED ---SIEQTLAELERRHGGRLGVAILDTGHQRLI-AHRGDERFAMCSTFKALTAAYVLARVD -RKEEDLSRVIVYGKEQLVPYSPLTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP -PALTAWLRSTGDQVTRLDRREPDLNENHAGDPQDTTTPIAMLQSLRTLILGDVLSGASRD -QLIAWLVSNTTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAVIWPPNRAPLIVTVYYTG -AKATGDQINALMADVGRLVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Geothrix fermentans TaxID=44676 RepID=UPI000411D01D -----PARLAALEARAGGRLGVAALDTGTGRRI-AHRGEERFPMCSTFKVLLAGAVLARVE -KGQERLDRPIAYTKSDLLEYAPVAAARLAEGMTVEALCAAAVEASDNTAANLLLQALGGP -GEVTAFARGLGDPVTRLDRTEPTLNTALPGDPRDTTTPAAMVESLKAMLLGGGLEPDSCQ -RLEGWMRGSLTGGDRLRAGLPATWTIGDKTGTGDRGTVNDVAILRPPGRAPILVAAYYTG -SRAPLKDRNAVLAEVGRIVAAAf ->[subseq from] class A beta-lactamase n=1 Tax=Jiella sp. R10 TaxID=2606717 RepID=UPI00131C4CF6 --dALAAQLSEIEAGLGARLGVSILDTGSGKRW-EHRASERFPLCSTFKALGAAAVLARVD -TGEESLDRRVRFAASDLVTYSPVTETQAGGAMTMAEICHAAVTRSDNTAGNLILKSLDGP -AGFTRFLRSIGDAQTRLDRWETELNDVPPGDPRDTTTPAAMTDSLARVVLGDVLSPASRE -TLSGWLVANTTGDKRLRAGLPKSWRVGDKTGTGDRGVANDVAVIWPPTGAPIVASVYIAD -TTASLDARNAAFAEIAAG----- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GD10_KLEPN --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIRAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00122E0724 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTX -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTB2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADGRFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALRYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRGTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera intermedia TaxID=61648 RepID=Q5MD18_KLUIN --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYFTQ -PEQKAESRRDVLA---------- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BC059 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQQ -QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6IT48_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERETTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI000F7067D5 ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAILKQSE -SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAATKIVTE-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C6C8872 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00001113F3 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKAGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase TEM-102 n=1 Tax=Plasmid pWW100 TaxID=167474 RepID=Q91UY8_9ZZZZ ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAVGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E5LP65_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q4U457_ENTCL ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGVTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L7B531_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQVTMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZB6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVMLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=B5THT3_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGGILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodoplanes sp. Z2-YC6860 TaxID=674703 RepID=A0A127ER68_9RHIZ ---TLKAELTRIELESGGRLGVAVLDTGSGARV-DHRGDERFPMCSTFKLLGAAAVLKRVD -GGQEKLERRIVFSAKDIVANSPITEKHVGGDMTLAEICEAAMTVSDNTAGNLILKSLSGP -KGITDFARTLGDSMTRLDRFETELNEALPSDPRDTTTPLSMLGNVQKLVLGDALSAGSKD -QLTKWLLANKTGDTRVRAGLPAGWRTGDKTGSGERGTTNDIGVLWPPDGAPIVVTIYLTG -TQASAENRNATLAAVGRAIVS-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P9E6A6_ECOLX -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. GW103 TaxID=1175306 RepID=I3CQ40_9BURK ---TLTDTLSRLEADIGGRLGVSLVDTAGARHW-GYRADERFPMCSTFKFLAAAAVLHRVD -QGKEQLSRRIVYHQKDLVPYSPTTGKHTGGALSMAQLCEAAMTLSDNTAANLMLASMNGP -AGLTRFVRTLGDDLTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRRLLLDDALAPASRQ -QLTQWLVANRTGDQRVRAGLPAGWKVGDKTGTGRLGTANDVGVVWTDKGAPLLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A291NXX5_9ENTR --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP -GKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGNALGDTQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -PKPKAESRGDVLAAAARIVTDGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ97_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPAAWVVGDKTDSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. YR568 TaxID=1855301 RepID=A0A1I7H6I5_9BURK ---AVSARLKALERESGGRLGVSVLDTANGARW-GHRAGERFPMCSTFKLLAAALVLHRVD -AGQEQLARKVIVKASDIITHSPTTKQYVGPQITIAQLCEATITLSDNAAANLLLATFGGP -QGLTAYTRSLGDTMTRLDRNEPSLNEATTGDKRDTTTPDAMVTTIQKIALGTVLSEASRK -QITQWLLDNKTGDNRLRALLPAGWRVGDKTGTGGHGSTNDVGILWPPGRAPLVVAAYLTG -TSRPIAQREAVLAKVGELAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum rubrisubalbicans TaxID=80842 RepID=UPI00077C3A24 ---AISARLARLEADIGGRLGVSLVDTVGARQW-GYRADERFPMCSTFKWLAAAAVLRRVD -EGREQLTRRIVYHQRDLIPYSPTTGKHVDGTLSLAQLCEAAVTLSDNTAANLMLASMGGP -AGMTAFVRTLGDALTLLDRNEPTLNQAVPGDPRDTTTPAAMTADLQRLVLGDVLTPASRA -QLTQWLLANQTGDKRVRAGLPAGWKVGDKTGTGRLGTANDVGVAWTPQGKPLLFAVYLTE -NAADDARRDALHAEVGRLIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2S1T3T7_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQSTMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0007DE0EF1 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGHEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Cobetia sp. TaxID=1873876 RepID=A0A2E4Q4C2_9GAMM ------SAIQAIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD -EGQESLSRKVAIRPADLVTYSPITEHHTRDGLTLEALCHATITTSDNTAGNLILDALGGP -AALTAYLRRLNDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL -ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE -SEADLAARNAAIADVGRLLVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum autotrophicum TaxID=180195 RepID=UPI0012ECD314 ---SAQKKLAALEKESGGRLGVAALNTADGAQL-LHRGDERFAFCSTFKVIAASAILTRSN -ADAGLLQRRIRYTKAEMVNYSPITEKHLADGMTVAELCAAALQYSDNSAVNLLMKILGGP -EAVTAYARSIGDREFRLERWETMLNSAIPGDPRDTSTPVAMMHDLQRLVLGDALTPAQRE -QLRIWLLGNTTGATRIHAGVPAGWQVGDKTGTGDYGTTNDIGVVWPSGTAPLVIALYFTQ -NTQDAAPRNDVLASATRVVIDAf ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root318D1 TaxID=1736513 RepID=A0A0Q6N2I5_9BURK ---SAEAELAALESSVGGRLGVAALDTATGARV-QHRAAERFPLCSTFKTMLAAAILDRST -RDGSLLERRVSYGKGDILPHSPITEKYLGQGMTVSAMCAATIQYSDNAAANLLMKILGGP -SAVTAYARSIGDQAFRLDRWETELNSAIPGDPRDTTTPEAMAASLQRLVLGDALGAAKRS -QLETWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDTGVLWPPVGAPLVLAVYLTF -PTKDAEGRNDVIASAARIAVN-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0011C9592E -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SFO family class A extended-spectrum beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A1Q5VB22_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMVIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTSWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH64 TaxID=652740 RepID=A0A2U1XMM0_9PROT ---AFAARMSELEGRTGGRLGVAVLDSANGRLQ-DWRGDERFPMCSTFKFLLAAAVLKSVD -QGKDRLDRRIAVTKADLVPYAPFSETRLNGTPTLAELCEAAVTLSDNVAANLLLPGVGNP -AGLTAFLRGIGDKVTRLDRNEPSLNTAIPGDPRDTTTPAAMVRSMERLLVGDVLRPDSRK -QLTDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTH -TAKDFKQQDAIHADVARAVA--- ->[subseq from] Class A beta-lactamase SFO-1 n=5 Tax=Enterobacteriaceae TaxID=543 RepID=A0A126E3U4_ECOLX ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP -AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092C7AEC ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLHNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLA---------- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P1MSP3_ECOLX ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -MDKNLLAKRMEIKQSDLVNYSPIAEKHLDTGMTLAELSAATIQYSDNTAMNKILEHLGGP -AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPATWVVGDKTGGGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RMN1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHHTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=Q8GP08_PSEAI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001072674F ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] FONA family class A beta-lactamase n=1 Tax=Enterobacter ludwigii TaxID=299767 RepID=UPI000A3AC462 ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP -AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C4PE86_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=5 Tax=Enterobacterales TaxID=91347 RepID=Q8VP43_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Brucella melitensis TaxID=29459 RepID=UPI001071E4F4 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A3P0CSY7_9BURK ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAASLRVLALGDALPAPQRA -QFAAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWSPAGGPVALAVYYTQ -AKDD------VIAAATRIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Fulvimarina sp. TaxID=1969479 RepID=A0A2E1HKF6_9RHIZ ---AITETIAAVEKRLGARVGAVIIDTQSGRTW-SHRAQERFPLNSTFKAFACAAVLAEVD -AGKAALDKHITFTADDLVTYSPVTETRVEAGMTLGEVCDAAMTMSDNTAGNLVIESLGGP -DGVTRFMRQIGDAETRLDRTEPTLNEATPGDPRDTTTPEAAATSLRELVLGDALSPRSRR -QLETWLLGNKVGDPLLRAGLSKDWTIADRTGAGGHGSRSIVAIAWPPERKPVVAAIYLTG -TEASMEERSAAIAEIGTAIAR-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6W7J4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEQNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=B6E296_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Elstera cyanobacteriorum TaxID=2022747 RepID=A0A255XSG8_9PROT ---TLTQTIIDLETRLQGRFGVLIHDTETGKRW-QHRADERFPMCSTFKYVLAAAILARVE -AGEDKLDRRLPITAADLVPYAPVTQPQVGKTLTLAELCHAAVTVSDNTAANLLLRVLGGP -AALTGFLRRIGDNVTRLDRWEPELNSALPGDPRDTTTPAAMTRTLENLLLGPALTPASKT -QLTLWLIANTTGDAKVRAGLPKSWRVGDKTGSGARGTMNDVVAIWPPQRKPVLLSLYLTE -TKASMEDRNAAFAAVGTAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000CFE7B69 ---DAARQIAALESGFGGLIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADKTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHD0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=Q8VN22_9ENTR --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSVDYGPTTHIAIIWPENHAPLVLVTYFTQ -PDQKAESRRDVLAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q1UDC3_RHILE ---DIQRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTAWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTAPVKELNPVFAEVGRMIVE-- ->[subseq from] Extended spectrum beta-lactamase TEM-63 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFEF ---ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI0010E5F4AD -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPVRIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1B2H7A9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDDMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2R4PD66_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -GQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9RN48_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASQQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT55W TaxID=2666083 RepID=UPI0012AFAF71 --------LARLEKESGGRLGVAALNTADGRQL-TYRADERFPMCSTFKMMAAAAILARDP ----ALLKKRIQYEKSDLVPNSPVTSKHVAEGMAVAELCEATLQYSDNAAANLLMKQIGGP -VAVTAYARSIGDNEFRLERWETELNSAIPGDARDTTTPLSMARSLHKLVLGEALPAPQRR -LLKEWMVGNTTGATRIRAGVPAGWTVADKTGAGDYGSVNDIAVIWPPGRAPIVLAVYLTQ -PGKDDKLRPEIHGEVARVAIEAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A4Y5UM98_PSEAI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLRNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Verrucomicrobium spinosum TaxID=2736 RepID=UPI000492C51E ------SKLEGVEGSSGARLGVYALDLESGMEV-SRRTEERFPVCSTFKVMLTAAILKQSV -QDAGLMTRRVSYAKEDLVTYSPVTEKHVEGGMTVEALCAAAMQYSDNTAANLLMKILGGP -GAVTAYARSIGDTQFRLDRWETELNTALPGDPRDTSNPAAMGHSLQKLALGDGLPEAQRA -KLVEWLQGNTTGDKRIRAAVPPGWKVGDKTGSGDYGTANDIAILWPPGRKPIVLAIYHTQ -KAADAKWQNEVVAAAARVVLEAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D9IQH0_ECOLX --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0E3XAI9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=15 Tax=Bacteria TaxID=2 RepID=D2I9G2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0P0H9J6_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8KQ59_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A4Y5ZMM5_9ENTR ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQQA -QLVTWMKGNTTGAASIQAGLPASRVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A286SCJ4_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKRw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI000E69F2B3 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAALIKHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=I6VD99_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q844X1_KLEOX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SS60_9BACT ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWVIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Cobetia sp. UCD-24C TaxID=1716176 RepID=A0A0N8HJC7_9GAMM ------SAIQDIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD -EGQESLSRKVAIRPADLVTYSPITENHTQDGLTLEALCHATITTSDNTAGNLILDTLGGP -AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL -ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE -SEAELAARNAAIADVGRLLVK-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2I8ANK3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTIPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=M5B5Q1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia plantarii TaxID=41899 RepID=A0A0B6S782_9BURK ------RQLAALDGSFDGRIGVAALDTGSGARL-LHRADERFAFCSTFKTILVSAVLTRAA -GDPRLLSSVIRYRAQDLVRYSPVSEKHVDTGMSVAGLCAAALQYSDNSAANLLIRMVGGP -AAVTAYARSIGDRRFRLDRIETELNDAVPGDERDTTTPAAMLDTLRRVTLGDALDASSRA -RLISWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLVVYTTR -DRKDAEYDNAAIASAARIVTAAf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E353152 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=J9YNF9_ECOLX ---ETVVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -GQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase FONA-2 n=2 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR2_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDPRDTSSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] BETA-LACTAMASE TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000112089 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAAERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangdongense TaxID=1325090 RepID=A0A410V6N9_9BRAD ------EALKQLESKSGGRLGVSVLDTTTGIPI-HHKGDERFPMCSTFKVLAAAAILKDVG -SKLEGLERRVRIEQADLVASSPVTSKHVGGDMTLRELCDAAITMSDNTAGNALLKNIGGP -AGLTSFARSLGDDITRLDRTETELNEATPDDPRDTTTPNAMAANYRRLLLGDVLPPEGRD -QLGKWLIANKTGDTRLRAGLPQGWRVGDKTGAGEHGTCNDVAIVWPRERSPLIIAVYLTG -ATLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. yr520 TaxID=1761779 RepID=A0A329D8P7_9BURK ----AASRLKALEDASNGRLGVSALNTADGARI-DYRADERFPFCSTFKVVLSSAILTRSA -RDEGLLARRIRYAQSDIIANSPVTSKHVADGMTVGELCAAALQYSDNAAANLLIRLLGEP -ADVTAYARSIGDTEFRLDRMETELNTAIPGDPRDTTTPAAMALTLQRLALGNALGVAQRD -QLQAWMRANTTGDKRIRAGVPRDWQVADKTGTGDYGTSNDIAVLWPPARPPIVLVIYFTQ -REQDAKARDDVLASAAKIVAEKf ->[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A4Q5Q991_9GAMM --dLLTQRLAELEKKLGGRLGVFILDTQTGKHW-AQRANERFPMCSTFKLIACGAVLAKVD -AGKEDLNRRVYFEKNDLVANSPITEKHAGSEMTFAEICEAAITRSDNTAANIILKSLNGP -SAVTAFARTLGDSVSQLDRYETELNEATPGDIRDTTSPSAMAGNVNKLLLGNTLTIKSRE -QLKTWLVANKTGDAKLRAGLPKEWIVGDKTGAGSYGTTNDVAIIWPTNRKPIITSIYITE -PKVSFDECNAAFAEIGRAITA-- ->[subseq from] class A beta-lactamase n=1 Tax=Duganella radicis TaxID=551988 RepID=UPI0012D738B0 --------LARLEKESGGRLGVAALNTADGRQL-LHRADERFPFCSTFKMMLSAALLAREP ----ALLKKRIAVDKSDLVPHAPITSKHVGEGMTVAELCEATLQYSDNPAANLLMKQIGGP -AAVTAYARSIGDNEFRLERWETELNTALPGDTRDTTTPLAMAKSLQKLVLGDALPSPARK -QLKDWMLGNTTGATRIRAGVPSGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ -PGKDDKLRPEIHGEAARIVIEAf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DDA6C2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAILSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A565FB41_KLEPN ---ETLVKVKDAEDQLGAQVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter sedlakii TaxID=67826 RepID=UPI0005A60EA7 --qQVQKKLAALEKQSGGRLGVALINTADNSQV-LYRADERFAMCSTSKVMTAAAVLKQSE -THDGILQQKMTIKKADLTNWNPVTEKYVGNTMTLAELSAATLQYSDNTAMNKLLAHLGGP -GNVTAFARSIGDTTFRLDRKEPELNTAIPDDERDTTSPLAMAKSLRKLTLGDALAGPQRA -QLVDWLKGNTTGGQSIRAGLPARWVVGDKTGAGDYGTTNDIAVIWPEDRAPLVLVTYFTQ -PRQDAKWRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=X5JYP1_ENTCL ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVMYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A173GQ32_9ENTR --nDIQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP -GKVTAFARVIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGNALGDTQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -PKPKAESRRDVLAAAARIVTDGy ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0B4UAY9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERSRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9AEY6_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTDELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium vignae TaxID=1549949 RepID=A0A4Q0R5M8_9BRAD ---ALIEAIKQLELKSGGRLGVSVLDTATGVPI-HYRGDERFPMCSTFKVLAAAAILKDAG -SRPERLERRVRIEQADIVENSPITREHVGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTNFARSLGDILTRLDRTETELNEAAPGDPRDTTTPNAMAANFRRLLLGDVLLPEGRD -QLGKWLIANKTGDTRLRAGLPQSWRVGDKTGAGEHGTTNDVAIVWPPEHSPLIIAVYLTG -ASLDSGGRNDVIASVGRAVAKGf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346ARK8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A/beta-lactamase class A CTX-M n=1 Tax=Rahnella sp. BIGb0236 TaxID=2485117 RepID=A0A4R7GN14_9GAMM ---SVQQQLAALEKDSGGRLGVMLINTADNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLTRRISLKKSDLVNYNPITEKHLDTGMTIGELAAAALQYSDNTAMNKLIEQLGGP -QKVTAYARTLGDNTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGTALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAKSRRDVLASAAKIVTQGy ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2A6EA8 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLAQVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Meiothermus ruber TaxID=277 RepID=UPI0001922F8F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRLIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=B3LE91_9ENTR --nDIQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP -GKVTAFARVIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGNALGDTQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -PEPKAESRRDVLAAAARIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. RFA10(1/100) TaxID=2511202 RepID=UPI00101F0650 ---SVQQQLAALEKDSGGRLGVMLINTEDNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRHVSIKKSDLVNYNPIAEKHLGTGMTIGELAAAALQYSDNTAMNKLIGQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVALGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLILITYFTQ -PEKNAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase TEM n=17 Tax=cellular organisms TaxID=131567 RepID=A0A0F8NV65_METMZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium jicamae TaxID=280332 RepID=A0A0R3LP72_9BRAD --qRLIDEIKRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKALAAAAILARVD -AGKEQLTRRVTFEASALVTYSPVTEKHAGRDMTLAEICEAAVTLSDNTAGNLQLASIGGP -SGLTSFARSLGDQITRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALVVGTALSAPSRE -QLTAWLVANKTGDTRLRAGLPKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITGYLTG -ATVPAAQQNAIWASVARAVS--- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=A0A1N6RYZ4_9BURK ---EAHAALQALDDRFDGRLGVFALDTGSGATL-GHRGGERFPMCSSFKAVLAASMLARSS -RQPDWLAHRVRYAKADLVSYSPVTERHVGEGMTVAELCAATVQYSDNGAANLLMAQSGGP -QALTAFARSQGDSTFRLDRIEPALNSAIPGDERDTTTPEAMARLLQRLVLGEGLPPQERQ -QLADWLRGNTTGARRIRAGMPAAWTVGDKTGTGAHGSASDIGIVWRPGAAPLALAIYTTR -PAADAPADEAVIAEAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0C5C5N5_PROMI --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE -TQKGLLSQRVEIKPSDLVNYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] Beta-lactamase n=3 Tax=Escherichia coli TaxID=562 RepID=Q8GA85_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2DBC17 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] inhibitor-resistant class A broad-spectrum beta-lactamase TEM-31 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00042DA861 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSCGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=UPI0006203D3B ---SLHKQLTELENSTKGRLGVALINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM -SQPELLAKHIHYRESDLLSYAPIARKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL -EAVNRFTQGIGDPAFRLDRREPDLNSAIPGDLRDTTTPAAMAASVRKIVLGEVLGASQRE -QLIVWLKGNTTGDASIRAGTPADWVVGDKTGGGDYGTTNDVAVLWPPKGAPVVLAVYFTQ -PQQDAESRRDVLAAATRLVMAH- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI000FFB086C --eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIKELGGI -AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE -QLAIWLKGNTTGGETIRAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ -REKDAKPRRDVLAEATKMVLSH- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002CA84F9 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMGTTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT9W TaxID=2692178 RepID=UPI00136D7DEE --------LARLEKESGGRLGVAALNTADGRLV-LHRADERFPFCSTFKMMLSAAILAREP ----SLLKKRIQYEKSDLVPHSPITGKRLAEGMTVAELCEATLQISDNAAANLLMKQIGGP -AAVTAYARSIGDTEFRLERWETELNTAIPGDVRDTTTPLAMAKSLQKLVLGDALPAAQRK -QLKDWMLGNPTGATRIRAGVPSGWPVADKTGAGDYGTVNDIAVIWPPGKAPIVLAVYLTQ -PNKDDKSRPDIHGEVAKVVIEAf ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. TW-1 TaxID=2717319 RepID=UPI00141FAC03 ----ATRALADLERRAGGRLGVAAWRHGGAPVL-AWRGDERFPFCSTAKVMVAGAVLARAT -REPGLLDERVRYRAADLVAWSPVTEKHVDEGMTIAGLCAAALQASDNSACNLLLDRIGGP -AAVTAFARRIGDTAFRLDRRETALNTAIPGDPRDTTTPRAMARSLQALLLEEALAPEARR -RLLDWMLGNTTGKERIEAGVPAGWRVADKTGTGSYGTTNDVGIVFPPQGASIVVAIYYAG -ATPDAHSDSKVVADAAAIVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI0009B8C160 --qRLQQEFARIELATSGRLGVAALDMETGLRA-SRRGDERFPMCSTFKALASAAVLHRGD -RGESSLDQQIRFEAKDILANSPVTKEHVASGMTLAELCEAAITRSDNTAGNMILREIGGP -AGLTGFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVLGNVLQTVSRQ -KLADWMVANKTGDARLRAGVPRDWRVADKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMEKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. ORS 3257 TaxID=167468 RepID=A0A2U3Q2U2_9BRAD ---ALIEAIKQLELKSGGRLGVSVLDTATGVPI-HYRGDERFPMCSTFKVLAAAAILKDAG -SRPERLERRVRIEQADIVENSPITREHVGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTSFARSLGDILTRLDRTETELNEAAPGDPRDTTTPNAMAANFRRLLLGDVLLPEGRD -QLGKWLIANKTGDTRLRAGLPQSWRVGDKTGAGEHGTTNDVAIVWPPEHSPLIIAVYLTG -ASLDSGGRNDVIASVGRAVAKGf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00102E861F ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q93GI3_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=G1FK69_SALER ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Cupriavidus pinatubonensis TaxID=248026 RepID=Q470Y4_CUPPJ ---DAESRLATLERSAGGRLGVFARHTGDSRQV-RHRAEERFPFCSTFKVILAGAVLQRSA -GAPGLLDEHVRYTRQDLVAYSPITEKHVADGMTIAQLCAAAIQYSDNGAANLLMHRLGGP -AAVTGFARSIGDQTFRLDRWETELNTAIPGDPRDTSTPAAMAASLQALALDGALPPVQRN -QLQAWLRGNTTGAARIQAGMPAGWQIGDKTGSGDYGTTNDIAVLWPLAGAPIVVAIYFTQ -AAPDAKWSNETIASAARIAL--- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=R4NFA1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDFVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Serratia fonticola AU-P3(3) TaxID=1332070 RepID=U2M054_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPMAMAKSLQNLTLGKALAEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas pratensis TaxID=279113 RepID=A0A127Q7C5_9BURK ------EQLRQIEAKSGGRLGVAIFDSHSGQTY-AYRGGERFPMCSTFKLLASAFVLKRVD -QGKEQLTRRIRYQKADLVPYSPVTEHHTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP -AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGGNLSGTSRQ -QLTDWLLVNKTGDKRLRALLPSGWRVADKTGTGDQGTANDIGMLLSPDGAPLLVASYLTG -TPGPAAARDAVHAQVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas fungivorans TaxID=158899 RepID=A0A127P9K0_9BURK ---------RQIEAKSGGRLGVAILDTASGQSH-AYRGDELFPMCSTFKLLAAGLTLHRVD -QAQEQLARRIRYETAELVPYSPATEKHAGGDMSVAELCEATLTLSDNTAANLLLHSFGGP -TQLTAYLRSLGDKVTRLDRIEPDLNQATPGDPRDTTSPSAMLSTMQQLLLGNALSADSRK -QLATWLLANKTGDKRLRALLPAGWRVADKTGSGAYGSTNDIGMLLPPGRAPLLVAAYLTG -TKASEATRNATLAEVGRLAA--- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX85_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0007CCDF69 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain BisB18) TaxID=316056 RepID=Q214B0_RHOPB ---ALAASFAKIEATSGGRLGVAVLDTKSAALV-GYRLDERFPMCSTFKLIAAAAILARVD -AGTERLDRRLRIAPEDILSYAPTTKQHVGKDLSVAELCEAAIVLSDNTAANLLLTRLGGP -AALTRYARSLGDEATRLDRMEPDLNEATPGDPRDTTTPAAMARAVQAVAVGTALSPGSRD -RLITWLIDCKTGGARLRAGLPSSWRVGDKTGSGSHGSSNDVAVIWPQDRAPLIIAAYLTE -TAGSDDQRNATHASVARSIA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3G2M3D8_9BACT ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q0GMA4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEEHFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B40419E ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLAGGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] CTX-M type extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6J8G6_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCCTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGKTTGAASIQAGLPASWVVGDKTGSGDYGTTNDTAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Enhydrobacter sp. CC-CFT640 TaxID=2586908 RepID=A0A5C8PFG6_9PROT ---TLADTFKKIEADSGGRLGVAVLDTQTGTSA-GHRADELFAMCSSFKMLAAAAVLARVD -AGKEKLDRRVPVQASDIIPYSPAVKERVGGTMSLAELCAATVTLSDNAAANLILATFGGP -AAVTAFVRSIGDGVTRLDRTEPTLNEARADDPRDTTSPAAMAATIQKLVLGTALSAASRE -QLTAWLVGNKTGDARLRAGVPRDWRVGDKTGTCNSNTANDVGLAWPPGRQPVIMSVYLTG -ATVNADRQNAAIASVARAVAT-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D6D2D9 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase FONA-5 n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIQ8_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAISLQNLTLGKALAEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A9J5X3_HAEPA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9FAA2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F68E8ED ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTRQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000EF9DE41 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGVRGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD62F5 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGVSLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Blastochloris tepida TaxID=2233851 RepID=UPI0013EF2297 ---SLAAQLAGLERAHGGRLGVAILDTGSGRAA-AHRGDERFALCSTFKLLAAGLVLARVD -RGEERLDRRIAYDAAALVPYSPITGPHAGEGLTVGALCEAAVTLSDNTAANLLLDSFGGP -AALTAYLRSLGDAATRLDRREPALNEATPGDARDTTTPLAMLQTLRTLVLGEALSDPSRA -QLAAWLRANRTGDKRLRAGVPKNWQVGDKTGSGGHAATNDVGILWPPGGPPILVAAYYAE -SPAIEDARAAVLAEVGRLA---- ->[subseq from] class A extended-spectrum beta-lactamase TEM-5 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00042D5403 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. OV458 TaxID=1855290 RepID=A0A1G7US83_9BURK --------LARLEKESGGRLGVAALNTADGRQI-LHRADERFPLYSTFKMMLAAAVLSREP ----ALTKKRIQYDKGDLVPHSPVTGKHVADGMTVAELCEATLQYSDNAAANLLMKQIGGP -AAVTAYARSIGDNEFRLDRWETELNTALPGDVRDTTTPLAMALSLQKLVLGESLPTSQRR -QLKDWMIGNTTGATRIRAGVPAGWTVADKTGAGDYGTVNDIAVIWPAGKAPIVLAVYLTQ -PNKDDKYRAEIHGEVAKVVIEAf ->[subseq from] Beta-lactamase n=1 Tax=Blastochloris tepida TaxID=2233851 RepID=A0A348G1S1_9RHIZ ---SLAAQLAGLERAHGGRLGVAILDTGSGRAA-AHRGDERFALCSTFKLLAAGLVLARVD -RGEERLDRRIAYDAAALVPYSPITGPHAGEGLTVGALCEAAVTLSDNTAANLLLDSFGGP -AALTAYLRSLGDAATRLDRREPALNEATPGDARDTTTPLAMLQTLRTLVLGEALSDPSRA -QLAAWLRANRTGDKRLRAGVPKNWQVGDKTGSGGHAATNDVGILWPPGGPPILVAAYYAE -SPAIEDARAAVLAEVGRLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. SJZ099 TaxID=2572916 RepID=UPI0011A69C0D -----VQQMAKLESGVNGRLGVFILDTAKGRQW-GYRADERFPMCSTFKFLASAAVLKRVD -QGEERLERRIVYTKESLVPYSPATGKHTGGNLSMSQLCEAAMTLSDNTAANLMLESLGGP -AGLTAFIRSLGDDLTRLDRNEPTLNESLPGDPRDTTTPAAMVADLRKIVLGNALNPASRT -LITQWLLDNQTGAKRVRAGLPTGWKVGDKTGTGSHGSTNTVGVAWTPQGVPLLFAVYLTE -TGADEAQRNGLHAAIGKLIAA-- ->[subseq from] Beta-lactamase SFO-1 n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A3G1NHF3_CITFR ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVIAVSALLKQSE -MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP -AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX91_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2MJV7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00141A51A4 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A345N859_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H2ERK9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8FEBC ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZR6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8RNX7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=68 Tax=Bacteria TaxID=2 RepID=Q7X575_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010354915 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013748C39 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX83_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8F9B7 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. GV023 TaxID=2135490 RepID=A0A3D9JT79_9BURK --------LARLEKESGGRLGVAAFNTADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP ----SLLEKRIRYEKSDLVPHSPVTGKHVAEGMTVEALCEATLQYSDNTAANLLMKQIGGP -AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR -QLKDWMIGNTTGATRIRAGVPAGWIVADKTGAGDYGTVNDIAVIWPPGRPPMLLAVYVTL -PGKDDKARVELHGEVAKVAIEAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00080289D7 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTH5_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI0003608796 ---NAQAQLAALESSVGGRLGLAAFDTASGARV-QHRATERFPMCSTFKMMASAAILARSS -REPGLLEQRVSYARSDILPNSPITEKNLGQGMAVSALCAATIQYSDNAAANLLMKILGGP -SAVTEFARSIGDAVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLGAAQRS -QLAAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIAVLWPPAGAPLVMAVYLTF -PQPDAPGRNDVIASAARIAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=S4TWB0_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0007DCEA2F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTMG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E9AE1F ---SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2W1_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVGDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010ABBBC7 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEARPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A081M7B9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140G9J4_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTAGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVL----------- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A242M2Z2_9BURK ---KISKRLARIEASTSGRLGVSVLDTGSGAHA-GLRADEAFPMCSTFKFLAAGFVLARVD -KGEEDLRRKIVYSKSDLVDYSPVTQHHADSALSVAALCEAAITLSDNTAANLLLASFGGP -AALTAFVRTLGDTQTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA -QLRDWLIANKTGAKRIREKLPKDWRVGDKTGTGSHGSTNDIAIIWPPKRAPLLVTAYLTQ -TSAQTARREAAIADIGGLVVSSf ->[subseq from] Class A beta-lactamase n=1 Tax=Yersinia massiliensis TaxID=419257 RepID=A0A2R4NWH8_9GAMM -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNAAMNLILTQLGGP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQNRREILAEAAKIAVSPf ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. GDM18 TaxID=2545469 RepID=A0A4R1C7B6_9GAMM ------SAIQDIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD -EGQESLSRKVAIRPADLVTYSPITENHTQDGLTLEALCHATITTSDNTAGNLILDTLGGP -AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL -ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE -SEAELAARNAAIADVGRLLVK-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter shengliensis TaxID=1389223 RepID=A0A2T1KNZ8_9ALTE -hnSLIKTVEKVADDLEARVGFAACDLESGQRW-EYHADQRFAMSSTFKTLACAALLHRVD -AGQENLAKKVNVSESDLVTYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE -QLRDWLKGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ -TEASFEERNAAIAEIGKAIV--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B2D13 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARNTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVEDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=S5FWH2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=Q2XPR0_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8KRH0_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Epibacterium mobile TaxID=379347 RepID=UPI00080739CC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPGAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E1FEE9D ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E3482D ---SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001110E054 ------EQIKQSENQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A097A289_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVFIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D9Z4Z4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=Q8GHI3_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSCGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G9FYZ8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNNERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus funiculus TaxID=137993 RepID=UPI00101D5BA7 ---ATSRKFVQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYTSTFKALAAAVVLQQNS ---IDKLDEVITYTKDDLVTYSPITEKHVDTGMTLREICDAAIRYSDNTAGNLLMQKLGGP -NGFEKALRQIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNDKRT -ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTH -DTKNATYNNELIAKAAKIALNVf ->[subseq from] Beta-lactamase L2 n=5 Tax=unclassified Bosea TaxID=2653178 RepID=A0A653PVI7_9BRAD ---KVREALFALDRKHGGRLGVAILDSSNGRIV-AHRGEERFAMCSTFKLVAAAFALARVD -RGEEELERRVSYSKADLITYSPVTEKHVEKGLTIAEICDAAVTLSDNTAGNLLLDSFGGP -QGLTDYMRSLGDEASRLDRREPDLNEAKTGDPRDTTTPVAMAGVLRQIVLGGALSPASRQ -QLTTWLVANKTGDKRLRAGVPKGWRIGEKTGTGNNNATNDVGVIWPPGRAPLVVTAYYAE -SSAAFPEREAVLAEVGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q933Z8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKLw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. th.b2 TaxID=172088 RepID=UPI000A06DF7E ---RLQQEFARVELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRVQIEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILREIGGP -AGLTSFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVIGDVLQATSRQ -RLIAWMVANKTGDARLRAGVPRDWRVGDKSGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus (strain S110) TaxID=543728 RepID=C5CR04_VARPS ---SAEAQLAALERSVGGRLGLAAFDTATGARV-QHRATERFPMCSTFKMMASAAILARSS -REPGLLEQRVSYARSDILPNSPITEKNLGQGMAVSALCAATIQYSDNAAANLLMKILGGP -SAVTEFARSIGDAVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLAAAQRS -QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIGVLWPPAGAPLVMAVYLTF -PTPDAPGRNDVIASAARIASD-- ->[subseq from] Beta-lactamase n=2 Tax=Serratia fonticola TaxID=47917 RepID=BLAC_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAISLQNLTLGKALAEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E40979 --eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIKELGGI -AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE -QLAIWLKGNTTGGETIRAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ -REKDAKVRRDVLAEATKMVLSH- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MUM 13 TaxID=1678001 RepID=A0A1S2RAA5_9BACI --aAAGRKFKQLEKKFDARLGVYAIDTGTNRTV-VYRPDERFAYASTYKALAAGLVLQQNS ---IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAANLLLQKLGGP -NGFEKALRKIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNDKRK -ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGSGDYGTRNDIAIVWPPNRDPIVITILSTR -DTKNATYNNELIAKAAKVALNTf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I616_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLaAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. PAMC 28687 TaxID=1795874 RepID=UPI000784351A ---KISKRLARIEASTSGRLGVSVLDTGSGAHA-GLRADEAFPMCSTFKFLAAGFVLARVD -KGEEDLKRKIVYSKSDLVDYSPVTQHHADSALSVAALCDAAITLSDNTAANLLLASFGGP -AALTAFVRTLGDTQTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA -QLRDWLIANKTGAKRIREKLPKDWRVGDKTGTGSHGSTNDIAIIWPPKRAPLLVTAYLTQ -TSAQTARREAAIADIGGLVVSSf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUK7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Providencia stuartii TaxID=588 RepID=V5LEG1_PROST ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVENSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RN76_9BACT ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEKLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q4F7H1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLPDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00128DECD7 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNDTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075MBC8_ECOLX ---ETLVKVKDAEDQLGARVGYIEMDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase CTX-M-4 n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=BLC4_SALTM --nSVQQQLEALEKSSGGRLGVAQINTADNSQI-LYVADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIRASDLVNYNPIAEKHVNGTMTLAELGAGALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNSAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGMPKSWGVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS018417 TaxID=2033491 RepID=A0A2A8S968_9BACI ---ATSRKFVQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYTSTFKALAAGAVLQQNS ---IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLQKLGGP -NGFEKALRQIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLSNDKRT -ILTDWMRGNLTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTH -DTKNATYNNELIAQAAKVALNAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L7B4G6_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A9L1_SHISO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=K4Q514_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTL8_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSAHSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=Q46029_CITKO ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGAGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 6(2017) TaxID=1197460 RepID=UPI0013E0F6B7 ---RLQQEFARVELATSGRLGVAALDMETGLRA-SQRGDERFPMCSTFKALASAAVLHRVD -RGESSLDQRVQIEAKDILANSPVTKEHVASGMTLAEICEAAITRSDNTAGNMILREIGGP -AGLTSFFRTIGDNVSRLDRWELALNEGVSGDPRDTTSPVAMLKNLQRVVIGDVLQATSRQ -RLIAWMVANKTGDARLRAGVPRDWRVGDKSGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMDKCNEVIANVARAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0E3JSK4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] SFO family class A extended-spectrum beta-lactamase n=1 Tax=Serratia sp. 14-2641 TaxID=1841657 RepID=A0A1C7W9S8_9GAMM ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTLGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWGVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0U3S9M4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI00044975E3 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMXTTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00081BEFE9 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAVLIEHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI000BE34AE8 ---AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDTTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGTGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B409F9A ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLASVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=8 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q79JA5_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=I6ZQ49_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNIGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium nanningense TaxID=1325118 RepID=A0A4Q0RZJ8_9BRAD ----LFDAVQQLEIKSGGRIGVAVLDTKTGASV-HHKGDERFPMCSTFKVLASAAILKGAG -DKLDRLDRRIRIEQADIVENSPVTREHVGPDMSLRELCEAAMTRSDNTAGNLLLKNMGGT -AGLTAFARSLGDNVTRLDRTETELNEAAPGDPRDTTTPNAMAENFRRLLFGNELMPESRD -QLAKWLIANKTGDKRLRAGLPQNWRVGDKTGAGEHGTTNDVAVVWPPLRSPLIIAVYLTG -ASLDMNGQNEVIASAGREVAREf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q4F7H2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLMRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL93_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] class A beta-lactamase n=1 Tax=Nevskia soli TaxID=418856 RepID=UPI0004A7104E ------ARFAAIEKRVAGRLGVAALDTASGRRI-GHRAAERFPLCSTFKFLAVAAVLKRVD -EGRENLDRRIGYSQGDLLEYAPITRQHEKEGMTVSALCAAAIEYSDNTAANLLLQSLGGP -SAIGRYAATLGDGVTRLDRTEPSLNEAVPGDPRDTTSPAAMVGDLRAILLGKALSPASLQ -NIQTWLVANTTGGSRLRAGLPADWRVGDKTGTGGHGATNDIAILWPPGREPILVAAYLTE -TAAPAAERNRALAEVGRIIAGSf ->[subseq from] Beta-lactamase FONA-4 n=3 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR0_SERFO ---NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q9RIR3_SERFO ---NIQQQLSELEKSSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CE58_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT134W TaxID=2692171 RepID=UPI00136DD812 --------LARLEMESGGRLGVAAFNTADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP ----SLLEKRIRYEKSDLVPHSPVTGKHVADGMTVEALCEATLQYSDNTAANLLMKQIGGP -AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR -QLKDWMIGNTTGAARIRAGVPAGWVVADKTGAGDYGTVNDIAVIWPPGRPPILLAVYVTL -PGKDDKARVELHGEVAKVAIEAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Neisseria gonorrhoeae TaxID=485 RepID=A0A1W5T935_NEIGO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPATMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Collimonas pratensis TaxID=279113 RepID=A0A127R1V8_9BURK ------EQLRQIEAKSGGRLGVAIFDSHSGQTY-AYRGGERFPMCSTFKLLASAFVLKRVD -QGKEQLTRRIRYQKADLVPYSPVTEHRTGAGMTVAELCEAAITQSDNTAANLLLHSFGGP -AQLTAYMRASGDKMTRLDRIEPHLNEAAPGDPRDTTTPSAMVSSLREILLGGNLSGTSRQ -QLTDWLLANKTGDKRLRALLPSGWRVADKTGTGDQGTANDIGMLLSPDGAPLLVASYLTG -APGPAAARDAVHAQVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2P9DUS6_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A3FFR8_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVALCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase TEM-238 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5S9EDG4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella huaxiensis TaxID=2153354 RepID=UPI000DD30D38 ---AIQRKLTDLEKSSGGRLGVALINTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE -VDNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP -DKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAEILHKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPAGWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=Q6PP89_KLEAE ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sartisoli TaxID=83784 RepID=A0A1H4HJU3_9BURK -----EAKLAALETSMAGRLGVAALNTANGATL-MHRADERFAFCSTCKVMIVSAILTRSA -KEPGFLQQRVRYTKADLVAYSPVTEQHVAEGMTIGELCAAGIDYSDNTSANLLIRIVGGP -AAVTAFARSIGDDTFRLDRWETELNTAIPDDPRDTTTPAAMLASVQRLALGDALGAPQRN -QLQAWMRANTTGGERIRAGVPAGWDVIDKTGTGDYGATNDVAVIWPPAKPPVVLVTYLSQ -RDRDAKSRSDVLAAAARIVVAAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9R2G5_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGVGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium cajani TaxID=1928661 RepID=UPI0012F8699B ---RLLDAIKQLEIRSGGRLGVAVLDTRTGASI-HHKGDERFPMCSTFKALASAAILKGAG -DKLDRLDRRIRIEQADIVENSPVTREHVGSDMSLRELCEAAMTRSDNTAANLLLKNMGGP -AGLTAFARSLGDKVTRLDRTETQLNEAAPGDPRDTTSPNAMAGNFRRLLFGNELMPEARD -QLAKWLIANKTGDYRLRAGLPQNWRVGDKTGAGGNGTNNDVAVVWPPQRSPLIIAVYLTG -ASLDMNGQNEVIASAGREVAREf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0011F3AC38 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGPRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S6KJQ2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] inhibitor-resistant class A broad-spectrum beta-lactamase TEM-37 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00042D3DC6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0G3IAZ6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALLEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007DDFF40 ---ETLVKVKDAEDQLGERVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus rhizosphaerae TaxID=297318 RepID=A0A1R1E524_9BACL -------------EEHGVGVSVDIEDLSGHETI-ELGSRDAYYSASIIKLALIATLMQEVD -AGQHSLDEMLTVKPEDVVGGAGSLQNKFPQEVTIGRLAKLMITQSDNTATNVLIGLV-GF -DKVNAFIKSQGFTVTHLGRKMMTPAKS--PAEDNYTSAPEMLTLLDRIYNAKVVSAKSRE -QILEWMKAQEV-NTKFGAVLQ-GKPIAHKTGELGD-VSHDVGYFLIPGR-EIAIAVLTKV -LKKAQELDNPYVQRIAKATYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus rhizosphaerae TaxID=297318 RepID=A0A1R1E524_9BACL --------------REGIRVSVGIKDLSGSAEV-LLGSLQSYMPASTIKMALVSTLMQQVD -KGTLTLDQKVTVEPDDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL -DKVQALMDQLGLKTMHLGRKMFAAA--PTPEQDNYIDAADLVTLLAKIYNHEFLSAQSSE -QIIHWMKAQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDVGYFLVPGK-EIAISVMTEV -TTEAQTIGNPVVQSVAKAVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q46954_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. NFR16 TaxID=1566248 RepID=A0A1H7BZX5_9PSED ---SLEQRLAALERRHGGRLGVAIFDTASERMI-SHRGDERFALCSTFKCLAVACVLARVD -RQQEDLSRLLVYGKEQLVPYSPTTEKHADGSLSVGSVCEAAITLSDNTAANLLLDSLGGP -QALTAWLRTIGDPATRLDRREPELNENRPGDLQDTTTPHAMLQTLNRLVLGDILSPASRD -QLIAWLVNNKTGDDKLRAGLPEGWRVGDKTGSNARNASNDVAVIWPPRRPPIIVTVYCSD -ARGSSDQLDALIADVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=G1FTI5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A5GXS5_KLEPN ---ETLVKVKDAEDKLGARVGYIEMDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=D2K8A9_ELIME ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLICGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3P5G766_ECOLX ---------KDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B3B5U5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAEIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Stella vacuolata TaxID=217070 RepID=UPI001152F881 ---ATQARLADLEARHGGRLGVSVLDTGSGQRI-EHRANERFAMCSTFKLLAASMVLSRVD -RAEERLDRRIRFTAADVVDYSPVTGPRAGGPMTMGEVCEAAMTQSDNTAGNLMLQSFGGP -AALTAYARSLGDPVTRLDRMETALNEAAPGDPRDTTTPAAMVDNLAQLALGPALSEPSRA -QLITWMVGNRTGDRRLRAGFPEGWRVGDKTGTGGHGSAADIAVVWRPERTPLVVAVYCAE -ATAPPERRNSLFEEVARVIA--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F6670D0 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPARMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Citrobacter rodentium TaxID=67825 RepID=A0A482PIC7_CITRO --qQVQQKLAALEKQSGGRLGVALINTADNSQL-LYRGDERFAMCSTSKVMVAAAVLKQSE -TRPAILQQKIPIKKADLTNWNPVTEKYVGKEMTLAELSAATLQYSDNTAMNKLIAHLGGP -GKVTAFARSTGDTTFRLDRQEPELNTAIPGDERDTSSPRAMADSLRNLTLGDALADTQRA -QLVAWLKGNTTGGQSIRAGVPAHWVVGDKTGAGEYGTTNDIAIIWPENRPPLILVTYFTQ -RQQDAKWRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum lipoferum (strain 4B) TaxID=862719 RepID=G7ZBA1_AZOL4 ----LAERLAVLEERTGGRLGVAMLDTGSGRLQ-GWRVDERFPMCSTFKFLLAAAVLKGVD -QGRERLDRRIPVTSADLVPYAPFAETRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGDP -AGLTAFLRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERLLLGDVLRPDSRR -QLSDWMIANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPENRPPLLVASYLTQ -TAKEFKQHDSIHAEVARAVA--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00096BC36E ------EQIKQSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A1YTM7_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI96_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKRSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=A0A0E3UVG0_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A0G4Q215_PROVU ---TIEEQLTTLEKNSQGRLGVALINTKDNSQV-TYRGDERFAMASTSKVMAVAAVLKESE -KQSGLLDNPITIKKTDLVPYSPITEKHLATGMTLAQLSVATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQNAKYRKDIIAKAAEIVTKEf ->[subseq from] class A extended-spectrum beta-lactamase TEM-6 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000016F27B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N0A6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKADRIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0014122B53 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID=Q6SQJ9_STREE ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAIATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. PS24 TaxID=2609961 RepID=UPI00140CAC78 -----SALFETLEGTAGGRLGVCAWNTADGRRI-LYRAEERFPFCSTFKVILAGAILAHSA -RVDGFLQRQVHYTKNDLVTYSPVTEKHLTDGLTVAELCAAALQYSDNTASNLLMKLLGGP -EAVTTFARSIGDRDFRLDRWETALNSALPGDPRDTTSPVAMAQSLHALALGDSLAVAQRE -QLQAWLRGNTTGAKRIRAGVPTDWQVGDKTGTGDYGTTNDVAVIWPSAGGPIVLAVYYTQ -LAADAKPRDDVIAAATRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9L8E2_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q2V9Y4_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3HUP1_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=C9DT08_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000DC7BF0C ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTAQRLSARSQQ -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli (strain B / BL21-DE3) TaxID=469008 RepID=UPI000181CC64 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRSEERFPMMSTFKVLLCGAILSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-42376 TaxID=2014076 RepID=A0A3G6UU07_9BACI ---ATRQKFGQLEKQFDARLGVYAIDTGTNRTV-VYRPDERFAYASTFKALAAGVLLKQNP ---IDSLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAANLLLQKLGGP -NGFEKGLREIGDHVTEADRFETDLNTAIPGDIRDTSTARALATSLKAFTVDGVLPNEKRA -ILTDWMRRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAVIWPPNRDPIIIAILSTR -DTKDATYDNELIAKAAKVALNAf ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q06DP4_ENTCL ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQSDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=Q9S679_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSLGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q0GMA6_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIDEIGASLIKHw ->[subseq from] Beta-lactamase n=6 Tax=Bacteria TaxID=2 RepID=A0A3Q8AXR7_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Yersinia enterocolitica TaxID=630 RepID=Q58G58_YEREN ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0002E6CCBB ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A649UII2_ECOLX --------LAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKI----- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E7AXL5_ECOLX --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI001249FB31 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SFO family class A extended-spectrum beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A292AHS8_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRADERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPITWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia phosphatilytica TaxID=2026176 RepID=A0A2S8H9V9_9BURK ------DAFADLERRAGGRLGVAAWRRGGGPVL-AWRGDERFPFCSTAKVMVAATVLARES -REPGLLDERVRYKKADLVSWSPVTEQYIDDGMTVAGLCAAALQHSDNSACNLLLDRIGGP -AAVTAFARRIGDTAFRLDRRETELNAALPGDARDTTTPRAMAHSLEALLVDEALAPDARR -RLLDWMLANTTGKERIQAGVPAGWRVADKTGTGAYGTTNDVGIVFPPQGQPVIVAIYYTQ -SAPDAQSDSKVVADAAAIVAQ-- ->[subseq from] BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000110CCD ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia heleia TaxID=634127 RepID=UPI0005AB4CA6 ---SLEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMQERFPMCSTFKVLLASAVLTRKD -HGKEDLARKIVYSPAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP -SAITAFARSIGDPVTRLDRNETTLNDAIPGDPRDTTTPAAMVANLRELLLGERLSSASRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIVWPTGRAPILVTAYLTG -AAASSAQRDAAIAQVGAVVA--- ->[subseq from] Uncharacterized protein (Fragment) n=4 Tax=marine sediment metagenome TaxID=412755 RepID=X1GP87_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Thalassospira lucentensis TaxID=168935 RepID=UPI000DED4AD7 ---DIVQTVRDLEGRLDARIGIAVMDTQNNQNW-HYRGDERFPMTSTFKALACAAILSRVD -EGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLILDALGGP -DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ -HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ -TDASFDARNAAIAEIGNAIA--- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q58G80_ECOLX --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=Erwinia toletana TaxID=92490 RepID=UPI00034C8963 --eTLAQQLRALEKSANGRLGVALIDSGSLREL-HYRSDERFAMASTFKALLAAAMLQQSV -KQPDLLKKRINYKQSDLVTYSPVTEKNLKQGMTIAELCAAAIELSDNAAANLLLREIGGP -QAITRLARESGDMKTRLDRWEPLLNSAIPGDARDTTTPRAMASNLQQLALGQALPAARQQ -LLITWLKQSQTGAESIRAGVPQGWVVGDKTGAGAYGTTNDVAIIWPPKGKPLILAIYFTQ -KHQHAEARRDVLASATRLVLAEw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Y6M3H9_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMEDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Yersinia hibernica TaxID=2339259 RepID=A0A481QBP2_9GAMM ----VGKQLAELERTANGRLGIAMINTANDHKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLDKHIHYHESDLLSYAPITRKNLAHGMTVSQLCAATVQYSDNTAANLLIKELGGL -AAVNQFARDIGDQMFRLDRQEPDLNTALPNDPRDTTTPAAMAASLQKLVLGDALLPAQRQ -QLATWLTGNTTGDATIRAGAPKDWMVGDKTGSGDYGTTNDIAVLWPPEGAPVVLVVYFTQ -REKDAQPRHDVLASATKILLSQf ->[subseq from] TEM-94 ES-beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFBF ---ETLVKVKDAEDQLGGRVGYIELDLASGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium phaseoli Brasil 5 TaxID=526949 RepID=A0A1W6GFA6_9RHIZ ---NIERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFTLARVD -KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEDIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAD -ATAPMKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=H7CHH5_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQAIMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A3FFR4_ACIBA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDARVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=Q1KY81_KLEAE ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGVRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A4S2I2N0_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0014330057 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFCTTWGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD01B6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRLIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000BF1D70A ---AIQQKLANLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVLNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=H6D9D5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEPLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase TEM-12 n=5 Tax=Enterobacteriaceae TaxID=543 RepID=BLAT_KLEOX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9S678_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=UPI00093FD87A ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005DF661A ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPLCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Bacteria TaxID=2 RepID=UPI000D1E9889 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8L1Y1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLGRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A370FP56_9BURK ---EAQAALKALDEGFDGRLGVFALDTGSGATL-SHRAGERFPMCSSFKAVLAASMLDRSR -RQPDWLSHRVRYAKADLVSYSPVTERHVGEGMTVAELCAATVQYSDNGAANLLMAQSGGP -QALTAFARSQGDDSFRLDRIEPALNSAIPGDERDTTTPEAMARLLQRLVVGEGLPPRERQ -QLGDWLRGNTTGARRIRAGVPAAWTVGDKTGTGAHGSASDIGVVWRPGRAPLTLAIYTTR -PKADAPADEAVIAEAARIVA--- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=D3VY77_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. PBL-E5 TaxID=434014 RepID=UPI00131863FA ---DLPAQLAEIERGSGGRLGVGVLDTATGQRA-GHREDERFPMCSTFKLLASALVLARVD -RHEERLERRVVFGARDLVDGSPITGQHAGGNMTMAELCEAAITRSDNTAGNMLLASFGGP -KVFTTYARSLGDTLTRLDRNETSLNEARPGDPRDTTTPAAMLGNLQKILVGDALSPSSRA -QLLRWLDANKTGDERMRARLPAGWKVGDKTGSGERGATNDIGILRPPGRAPILVTIYLTE -TEAPANARNATIASAGAAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. TaxID=1912094 RepID=A0A2E9W9V9_9PROT ---DIVQTVRDLEGRLDARIGIAVMDTQSNQNW-HYRGDERFPMTSTFKALACAAILSRVD -EGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLIMDALGGP -DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ -HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ -TDASFDARNAAIAEIGNAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A80_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127S9W4_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERYRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPK7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMVVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD3696 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVESSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0006BA0FF2 ---ETLVKVKDAEDQLGARVGYIELDLISGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=D0ES28_PROMI --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQSLRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=Reyranella massiliensis TaxID=445220 RepID=UPI0002D26626 ---DATPRFADLERRNGGRLGVAAFDSASGRRI-GHRSEERFPMCSTFKFLAAAFVLARVD -RGEERLDRRIVYSTQDLVTYSPVTKDHVGPALSVAELCDATMTLSDNTAGNLLLASFGGP -AGLTAYARSLGDQTTRLDRIETALNEGLPGDPRDTTSPVAMLGTMHRLLLGDALSAASRE -RLTGWLVANKTGDKRLRAGMP-GWKVGDKTGTGGNGSANDIAIVWPTGRAPLLVTVYYTG -STISDEARNEVIAEAGRIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALB2_ECOLX ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=D5LY09_SERMA ---ETLVKVKDAEEQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM-1 BETA-LACTAMASE n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000111743 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX89_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -TGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A4Y5ZN65_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFFAQHGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F62A9D0 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=bacterium 2013Ark19i TaxID=1561004 RepID=UPI000B80AB1B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00124A5D22 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI0007846F3E ---KAEAQLAALERSVGGRLGLAAFDTATGARV-QHRATERFPMCSTFKMMVSAAILARSS -REPGLLERRVSYARSDILPNSPITEKNLGQGMAVSALCAATIQYSDNAAANLLMKILGGP -PAVTEFARSIGDAVFRLDRWETELNSAIPGDPRDTTSPEAMAASLQRLVLGDGLAAAQRS -QLEAWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDIGVLWPPAGAPLVMAVYLTF -PTPDAPGRNDVIASAARIASD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9R771_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=O53043_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0U3EBL2_9GAMM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. SJZ130 TaxID=2572918 RepID=A0A542MJK4_9BURK -----VQQMAKLESGVNGRLGVFILDTAKGRQW-GYRADERFPMCSTFKFLASAAVLKRID -QGEERLERRIVYTKESLVPYSPTTGKHTGGNLSMSQLCEAAMTLSDNTAANLMLESLGGP -AGLTAFIRSLGDDLTRLDRNEPTLNESLPGDPRDTTTPAAMVADLRKIVLGNALNPASRT -LITQWLLDNQTGAKRVRAGLPTGWKVGDKTGTGSHGSTNTVGVAWTPQGVPLLFAVYLTE -TGADEAQRNGLHAAIGKLIAA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTM7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMSVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus pacificus TaxID=2026187 RepID=A0A3P1B1Y1_9BACI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Phyllobacterium sp. YR620 TaxID=1881066 RepID=A0A1H0V405_9RHIZ ---DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD -RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP -KGLTQYARSLGDATFRLDRRETELNEATPGDPRDTITPAHILKDLQKTVLGNALSKSSRD -QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD -PKGTADSRNEIHRKVASLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira lucentensis MCCC 1A00383 = DSM 14000 TaxID=1123365 RepID=A0A367VXU7_9PROT ---DIVQTVRDLEGRLDARIGIAVMDTQNNQNW-HYRGDERFPMTSTFKALACAAILSRVD -EGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLILDALGGP -DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ -HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ -TDASFDARNAAIAEIGNAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium TaxID=1909293 RepID=A0A354UWI0_9PROT ---TFARKLAGIEGAIAGRLGVAVREIGTGRHY-GYRADERFPLCSTFKVLACAAVLKRVD -GGQEDLNRRIRFGPGDLVTYSPVTKDHVGGDMTLGALCTAAMTQSDNTAGNLILASLGGP -GAVTAFARSIGDQVTRLDRTEPDLNTAIPGDPHDTTTPGAMAADLGRLVTEGCLSRNSRH -QLVTWLISNQTGGAKLRAGVPAGWRVGDKTGGGAWGTTNDVAVIWPPPRDPFVVCVYLTE -TKASFDARNATIAAVGRAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU6_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM14_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGATSIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q937J3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGA -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UCV1_9BACT ---DAATRIAAIEARIGGRIGVAALDTGNSKHV-EHRADERFPMCSTFKFLAAAAVLKRVD -EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLNAIGGP -AGLTNFVRTLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDMQRLLLGDALSEASRR -QLEDWLQRNETGGPMIRAGIPKNWVLGDKTGRGSNGATNDIAILRPPDRAPILLAIYFIG -STTPAKDREAAIAEVAKIVAESf ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=A0A2S1LUN0_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=163 Tax=root TaxID=1 RepID=Q79DR3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q8RPY9_ENTCL ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAVTMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium icense TaxID=1274631 RepID=A0A1B1UST1_9BRAD --qRLIDEIKRLERESGGRLGVCVLDTATDARH-VHRGDERFPMCSTFKMLAAAAILAQVD -AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLASIDGP -PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPNAMASNLQALILGTALSAASRE -QLTAWLVANKTGDTRLRAGLAKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITAYLTG -ATVSAAQQNATLASVARAVS--- ->[subseq from] class A extended-spectrum beta-lactamase TEM-16 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000016F836 ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Chimaeribacter coloradensis TaxID=2060068 RepID=A0A2N5E5S9_9GAMM ---TLAARLADLEHSANGRLGVTLIDTGNQQAI-SYRGDKRFAMASTFKVLLAGAVLQRSV -AQPGLLEKRIRYDRAVLQSYSPVTGKHLDDGMTIAELCAAAIEWSDNTAANLLLTELGGP -QTITRLARSLHDDKTRLDRWEPELNTAIPGDERDSSTPQAMAHNLQKLALGDALPPAQQQ -QLIAWLKGSQTGAKTIRAGVPAGWEVGDKTGSGEYGTTNDLAIIWPPHGKPLVLALYFTQ -QKADAQARRDVLATATRWVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUL1_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVLLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. SF2003 TaxID=2136172 RepID=UPI000D1BF112 ------SAIQDIESEVGARIGVTVLDTADGTRF-SWRGNERFPMSSTFKVLACGHLLSRVD -EGHESLSRKVAIRPADLVTYSPITENHTQDGLTLEALCHATITTSDNTAGNLILDTLGGP -AALTAYLRRLDDDSTRLDRRETALNEATPGDPRDTTTPHAMAATLQRLLVGDALSEPSRL -ALQGWMLANTTGDDKLRAALPDDWQIADKTGGGGYGTNNDVAILWPPLRAPLIVAVYLTE -SEAELAARNAAIADVGRLLVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q0GMA5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMAVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000A07E20A ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C7AUD6_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Undibacterium parvum TaxID=401471 RepID=A0A3Q9BPK5_9BURK -----RKKLRALEQSFDGRLGLFAINTANGMSI-GLRESERFPLCSTFKMMLAAAVLDKSR -QSAGLLEQVITYTEKDLLDYSPVTEQHLADGMTVAQLCAATVNFSDNAAANLLMKLLGGP -AVVTAFARSIGDQSFRLDRWEPDLNSAIPGDLRDTTTPEAMAVSLQRLTLGDALPKAERE -QLQTWLRASTTGASRIKAGLPADWQSGDKTGTGSYGTAHDIAVIWPPNRAPVVLAIYTKQ -HKKNANGRSDIVAAAAKIVS--- ->[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZD2_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCITSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLALAAKIVTN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Duganella sp. CY42W TaxID=2692169 RepID=A0A6B1IXA8_9BURK --------LARLEKESGGRLGVAAFNTADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP ----SLLEKRIRYEKSDLVPHSPVTGKRVAEGMTVEALCEATLQYSDNTAANLLMKQIGGP -AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR -QLKDWMIGNTTGATRIRAGVPAGWIVADKTGAGDYGTVNDIAVIWPPGRPPILLAVYVTL -PGKDDKARVELHGEVAKVAIEAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q93K43_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Proteobacteria TaxID=1224 RepID=UPI000011F58A ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSLRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLATIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGSLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0M3E4G9_VIBPH ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=UPI0007334E3E ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Bifidobacterium dentium TaxID=1689 RepID=UPI000C1C47A7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A120HUS0_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001071D71D ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Borrelia coriaceae Co53 TaxID=1313292 RepID=W5SXK0_9SPIR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Caballeronia udeis TaxID=1232866 RepID=UPI001060BF04 -----QDQLKQLESSAGGRLGVAALNTADGKQV-NYRADERFPLCSTFKLMLVSAVLEQSE -SQKGLLERRIHYARSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLMKLVGGP -ETVTAYARSIGDNQFHLDRWEPDLNSAIPGDPRDTSTPAAMARSLQRVTLGDALGTSQRS -QLQTWLLGNTTGAGKIAAALPAHWMIGDKTGSGDYGTTNDIGVIWPAGKPPIVLAIYLTQ -REQDAKARDDVVASAARIVVGAf ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI00094B8D3E ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGS -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAVMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIVLAH- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. 18069 TaxID=2681415 RepID=UPI00135783DB ---RFQQAVHQIEIDSGGRLGVAVLDTHSGLAY-AHRGMERFPMCSTFKFLAAALVLARVD -QGQEQLTRRIAVQASDIVPHAPATQPRVGGLMTMAELCDAAVTLSDNPAANLLLQSFGGP -QALTAYARSLGDDFTRLDRIEPDLNEALPGDPRDTTTPEAMLQTLRKIVLGDALSPTSRA -QIVRWLQDNKTGDRKLRAQLPAGWRVGDKTGGGGYGTNNDIGVLWPPGRAPILVSSYLTQ -TTADQATRDRALAQVGRLAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPN5_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Desulfovibrio alcoholivorans TaxID=81406 RepID=UPI0004973D7A --kALHAQLAALSREAGGRLGVAFLDPATGRRF-AFRGGERFPFCSTFKLVLVAAVLRKSQ -DEPGLLAQQVAYGQGDLLAWAPATRKALEQGMTVGELCAAAITVSDNTAANLLLDRIGGP -RALTAYARSLGDTAFRLDRREPELNTAVPGDPRDTTTPAAMARTVEKLVLGDALAAPQRR -QLADWLKGNTTGGESIRAGVPAGWTVGDKTGSGAYGTTNDVAVLWPPQGGPVVLAVYYTQ -PRKDAPARKDVLAAATRLVL--- ->[subseq from] Beta-lactamase class A n=3 Tax=Burkholderiales TaxID=80840 RepID=A0A4R1P271_9BURK -----QDQLKQLESSVGGRLGVAALNTADGKQV-NYRADERFPLCSTFKLMLVSAVLEQSE -SQKGLLERRIHYARSELLSWAPITKKQIATGMTVAELCAAALQYSDNTAANLLMKLVGGP -ETVTAYARSIGDNQFHLDRWEPDLNSAIPGDPRDTSTPAAMARSLQRVTLGDALGTSQRS -QLQTWLLGNTTGAGKIAAALPAHWMIGDKTGSGDYGTTNDIGVIWPAGKPPIVLAIYLTQ -REQDAKARDDVVASAARIVVGAf ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira lucentensis TaxID=168935 RepID=A0A358HR17_9PROT ---NIVQTVRDLEGRLDARIGIAIMDTQSNQNW-HYRGDERFPMTSTFKALACAAILSRVD -QGKENLERKVVFAKSDLVTYSPVTEKHVGAPMTIGALCDATMSLSDNTAGNLIMDALGGP -DGVTAFLRDIGDNTTRLDRREPELNEAVPGDLRDTTTPDAIARTLRDLVLGDVLSDPSRQ -HLKSWLVGNKVGGPLIRAGMPDDWVIGDRTGAGGYGSRGNIGIIWPTGRKPLVVAVYITQ -TDASFDARNAAIAEIGNAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000F530C32 ---DAARQIAALESGFGGRIGVSAIDTGSGRRI-LHRADERFALCSTFKVVLVSAVLARAT -GDARLLSSVIRYTRHDLVSYSPVTEKNLATGMTVAALCAAAIQYSDNTAANLLIRLIGDP -AAVTAYARSIGDASFRLDRLETELNEAVPGDERDTTTPAAMADTLRRVTLGDGLDPSGRA -QLVTWMLGNTTGETRIRAGVPAGWRVADTTGSGDYGTANDVAVLYSPSRQPVVLTVYTTR -PGKDAKYDNATLAAVARIVTATf ->[subseq from] Beta-lactamase n=1 Tax=bacterium A52C2 TaxID=1855383 RepID=A0A1H9K0F3_9BACT --dALAASFASIEKRLQARLGVAILDTETRRAW-KHRAAERFPLCSTFKLLAAGAVLAKVD -AGDEDPARRIRFGKADVVTYSPVTQHHVGDGMTLAEISAAALTQSDNTAGNLILDSIGGP -EAVTRFARSLGDEVTRLDRRETALNEATPGDPRDTTSPEAMVADLGALLLGPTLSGRSRE -QLAAWMVANETGGAKLRAGLPKDWRVGDKTGGGDHGAMADVAIAWPPNRKPVIAAVYITE -TEASFDDRNAAIAEIGRALA--- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0009B6836C ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTK-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=Q9ZFV9_MORMO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=A0A6B1TZ46_CITAM ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9RMS4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSGGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT109W TaxID=2692170 RepID=UPI00136D9D31 --------LARLEMESGGRLGVAALNMADGRQL-LHRADERFPLCSTFKMMLAAAVLARDP ----SLLEKRIRYEKSDLVPHSPVTGKHVADGMTVEALCEATLQYSDNTAANLLMKQIGGP -AAVTAYARSIGDSEFRLDRWETELNSAIPGDVRDTTTPQAMAKSLQKLVMGEALPLHCRR -QLKDWMIGNTTGAARIRAGVPAGWVVADKTGAGDYGTVNDIAVIWPPGRPPILLAVYVTL -PGKDDKARVELHGEVTKVAIEAf ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0B4U9Z7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus stellifer TaxID=169760 RepID=A0A089LYY6_9BACL ------------AEEHGVGVSVDIEDLSGHETI-ELGSQDAYYSASIIKLALIATLMQEVD -AGQHTLDETLTVKPEDVVGGAGSLQKKFPQDVTIGRLAKLMITQSDNTATNVLIGLV-GF -DKVNAFIKSQGFTVTHLGRKMMTPAKS--PAEDNYTSAPEMLTLLDRIYNAEVVSAKSRD -QILEWMKAQEV-NTKFGAVLQ-GKPIAHKTGELGD-VSHDVGYFLIPGR-EIAIAVLTKV -LKKAQELDNPYVQRIAKATYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus stellifer TaxID=169760 RepID=A0A089LYY6_9BACL -----------AAEREGIRVSVDIKDLSGGAEV-LLGSRQSYMPASTIKMALVSTLMQQVD -KGALTLGQKVTVEPDDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL -DKVQALMDQLGLKTMHLGRKMFAAAP--TPAQDNYIDAADLVTLLAKIYNHEFLSTQSSE -QIINWMKAQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDVGYFLVPGK-EVAISVMTEV -TTEAQAIGNPVVQSVAKAVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=BLAC_CITKO ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTCPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGAGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=Q0VTQ9_SHISO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas delhiensis TaxID=366289 RepID=A0A239MIR4_9PSED ------ERLKQLERDSGGRLGVAVLDSGDGRRF-GLREDERFPLCSTFKLLLAAAVLARVD -RGEEQLARRIVYGRGDLVPYSPVSERHVGKPLSIAELCEAAVTLSDNGAANLLLASLGGP -AGLTAWLRGTGDEVSRLDRNEPTLNEALPDDPRDTSTPRAMVATLQRLLLGDVLQSTSRA -QLDAWLAANRTGDKRIRAGLPPLWKVGDKTGTGERGTSNDVAILRPPGRAPILVAAYLTG -SPASAEKRDAVLAEVGRLA---- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00128F50F7 ---ETLVKVKDAEDQLGARVGYIELDLNSDKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=4 Tax=root TaxID=1 RepID=D9HTE8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIVEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q5PSW6_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSRGIIAALGPDGKPSRIVVIYTTG -GQATMDERNRQIAEIGASLIKHw ->[subseq from] FONA family class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=A0A4P8U435_SERFO ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -TDKNLLAKRMEIIQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGDKTGSGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=A0A2S9JE22_9RHIZ ----FETAFKDLEKASGARLGVSVHDTGSGKRI-GYREKELFAMCSTFKFFAAAAILSRVD -QKKEKLDRVIRYGKSDLVTYSPVTEKHVADGMTLSAICEAAITWSDNAAGNLMLDALGGS -QGMTDYARSLGDTISRLDRREPELNEAKPGDPRDTTTPAAMRENLEKTVLGTALSEPSRK -QLTDWLVGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD -PKGTPDSRNLIHQKVARLVADH- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoduganella sp. CY13W TaxID=2692176 RepID=UPI00136E10CB --------LTRLESDAGGRLGVFALNTADGQHA-QHRADERFPFCSTFKLMLAGAILARGP ----ALLKQRIRYSSSDLVSYSPISGKYAGKGMTVAALCAATLQYSDNTAANLLIQQLGGV -AAVTAFARSIGDQAFRLDRMETQLNTALPGDLRDTTTPAAMAESLNRLVLGDALAPLARK -QLKDWLLGNTTGDTRIRAGVPSGWLVGDKTGTGDYGSTNDIGIIWPPGKAPIVLAVYYTQ -QGKDDKARSEVIAEAARIALAAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas soli TaxID=1306993 RepID=A0A1H9E6N6_9PSED ----LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAILAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -SGLTAFTRSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG -TKADAPWNSETIAAATRVVVEAw ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas soli TaxID=1306993 RepID=UPI0009E049DD ----LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAILAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -SGLTAFTRSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG -TKADAPWNSETIAAATRVVVEAw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000846A7E5 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGVVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=E5Q900_ECOLX ------KQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium icense TaxID=1274631 RepID=UPI0009F27367 --qRLIDEIKRLERESGGRLGVCVLDTATDARH-VHRGDERFPMCSTFKMLAAAAILAQVD -AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLASIDGP -PGLTAFARSLGDQVTRLDRNEPSLNEALPDDPRDTTTPNAMASNLQALILGTALSAASRE -QLTAWLVANKTGDTRLRAGLAKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITAYLTG -ATVSAAQQNATLASVARAVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax gelatiniphagus TaxID=1194167 RepID=UPI00110D693F -----IDTVKQVENRLQARVGVAISDTDSGRRW-RYQADQRFPFASTFKVLACGALLHKVD -AGEEQLNRRVRYTKDDLVTYSPTTEQHVEDGMTLAALCEATITLSDNTAANLVLNAIDGP -AGLTAFLRGTGDTVTRLDRYETELNEGTPGDLRDTTTPDAMLDTLYTLLFGEVLSADSRR -QLLDWMKADRVADDLLRAGVPDNWTVADKTGAGGHGSRSIIAVMWPPQRGPVLAAIYLTE -ADASMDQRNAAIAEIGKALA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodospirillales bacterium URHD0017 TaxID=1380357 RepID=A0A1H8WN31_9PROT ---DATSRLAELERRNGGRLGVAAIDTASGHRV-DHRAEELFPLCSTFKFLAAALVLTRVD -RGEEKLDRRVVFAEKDLVTYSPVTKEHVTPGMSVAEICDAAVTLSDNTAGNLMLASFGGP -AGLTAYMRSLGDRTTRLDRIETELNEAKPGDPRDTTTPAAMLDTMQRLLIGDALSASSRD -RLIGWLLASKTGGKRLRAGLPADWRVGDKTGGGNNGTANDVAIAFPPGRAPILIAAYYTE -STISDDARNTVIAEAGRLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica I TaxID=59201 RepID=A0A3Z4SE10_SALET ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A9QW43_KLEPN ---ETLVKVKDAEDQVGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQTAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. CF313 TaxID=1144315 RepID=J2KK32_9BURK ---SAEAQLAELERASGGRLGVAGFHTGRGARI-QHRAHERFPLCSTFKLMLAAAVLERSA -KDASLLARRIGYGKADLVSWSPITEKHVADGMTVAELCAATVQYSDNAAANLLLKMLGGP -ATVTAFARGIGDQAFRLDRTEPELNTAIPGDLRDTTTPAAMSDSVQRLALGDALGTAQRD -QLTTWLLGNTTSAERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPVVLSVYLTF -PQKDAKGRSDVIASATRIVVA-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q6QR76_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Mesorhizobium sp. GR13 TaxID=2562308 RepID=UPI0010C0D850 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGVSLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000D3211A7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLQNLGDDVTRLDRWEPELNEAITNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8RNX6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000929FFE2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIDASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B41A5E9 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2WEB9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A79_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEQNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=bacterium RRLBTPL IV-3 TaxID=342579 RepID=Q3S2X0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGHSLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q8KRG9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGGRGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0008FC96A0 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMETTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. 770b2 TaxID=1566271 RepID=A0A1I5QU73_9BURK --qEASAQIAALESASGGRLGVVGFNTATGARV-QHRADERFPFCSTFKLMLAAVVLERSA -KEGGLLARRVSYSKGDLVTYSPITEKNIATGMTVAELCAAAVQYSDNTAANLLMKMLGGP -PAVTAFARSSGDDAFRLERWETELNTAIPGDLRDTTTPAAMAASVERLVLGNALGAAQRQ -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVLAVYLTF -PEKDAKGRNDVVASATRIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. BJB475 TaxID=2233914 RepID=A0A3E1RY90_9BURK -----AALLAKLEGESGGRLGVAALNTGDGRRL-LHRADERFPFCSTFKTMLSAAVLTREP ----ALLKKRVRYTKKDLVTYSPVTEKHVGKGMTVAALCEATLQTSDNAAANLLMQQIGGP -AAVTAFARSIGDMEFRLDRIETELNTALPGDPRDTTTPASMAESLHKLLLGDGLGAPQRK -QLKDWMLGNTTGDTRIRAGVPSGSLVADKTGTGDYGSTNDIGVIWQPGKAPIVLVIYLTQ -PGKDDKARSEILAEATRIVVEAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013303031 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QMLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=P78144_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEQNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A2S8Q369_PHOLU ---SLHKQLTELENSTKGRLGVALINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM -SQPELLAKHIHYRESDLLSYAPIARKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL -EAVNRFTQGIGDPAFRLDRREPDLNSAIPGDLRDTTTPTAMAASVKKIVLGEVLGASQRE -QLIVWLKGNTTGDASIRAGTPADWVVGDKTGGGDYGTTNDVAVLWPPKGAPVVLAVYFTQ -PQQDAESRRDVLAAATRLVMAH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=V5LVW5_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEFSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A4U9D1D7_RAOTE -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVVELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDVRDTTTPQAMANTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase SHV-2 n=13 Tax=Gammaproteobacteria TaxID=1236 RepID=BLA2_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0009AAC897 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE9_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B5A5T0_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEQNRQIAEIGASLIKLw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B4531 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNETLPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1S7BI72_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTNGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGTSLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5XUL7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERVVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter sp. LQ44 TaxID=1749259 RepID=A0A142FMG0_9ALTE -hnSLIKTVEKVADDLEAHVGFAAYDVESGQRW-EYHADQRFAMSSTFKTPACAALLHRVD -TGQANLSRKVHVSESDLVTYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE -QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ -TEASFEERNAAIAEIGKAIV--- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q5H739_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAVPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. RIT623 TaxID=2559075 RepID=A0A4Y8SML0_9PSED ---TVQHQLQQLEHSAGITLGLWALDTGSGKQL-AYRAEQRFAFCSTFKAVLAGAILHRSE -TDSGLLNRRIAYAAEQLVVYSPITEKHVGAGMTVAELCAATLQYSDNTAGNLLLEQVGGP -AGLTAFARQLGDPTFRLDRNEPTLNTALPDDPRDTTTPLAMGVTLQRLLLGDALAPAGRE -QLQAWLKGNTTGDARIRAGVPKGWIVGDKTGSGDYGVANDVGIVWPKGRAPWILVVFSRG -PQQSSPWNHEPIAAATRLVVQAw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=A0A2S4RYP2_CITAM ---TIKQKLTALEKSSGGRLGVALIDTADDSQL-LYRGDERFAMCSTSKVITAAAVLKQSE -DDKNVLHQKMSIKKSDLTNWNPITEKNVDGEMTLAELSAAALQYSDNTAMNKLIDHLGGT -DNVTAFARSIGDTTFRLDRTEPTLNTAIPGDERDTSTPLAMAKSLRNLTLGNALGATQRA -QLVEWMKGNTTGGKSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLILVTYFTQ -PQQDAKDRKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E10279 ---SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMIVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAVWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASVTKIILS-- ->[subseq from] Beta-lactamase n=26 Tax=Bacteria TaxID=2 RepID=A0A1B7K3V6_9ENTR --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKDLLSQRVEIKSSDLINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP -GKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] Beta-lactamase n=1 Tax=Duganella sp. CF517 TaxID=1881038 RepID=A0A1H8EDL4_9BURK -------RLVRLEAQSGGRLGVAALDTADGRQL-LHRADERFPFCSTFKMMLSAAVLAREP ----SVLQQTIRYDKAELVAHSPITERHLDGGMTIEALCAATIQYSDNTAANLLIRHLGGP -EEVTAYARSIGDRQFRLDRWETALNSAIPGDPRDTTTPAAMMASLHKLTVGEALPPAKRK -ILTDWLIGNTTGATRIRAGVPSNWTVGDKTGAGDYGTINDIAILWPPNKPPIVLAVYLTQ -PGKDDKARAEILGQAAKIVIDAf ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E44BE2 ---SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B9U2I6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -MPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. CCOS 191 TaxID=1649877 RepID=A0A0F7Y4A0_9PSED ----LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG -AKADAPWNSETIAAATRVVVEAw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B8XLK1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERIRQIAEIGASLIKHw ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0004503F16 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Vibrio ishigakensis TaxID=1481914 RepID=A0A0B8P936_9VIBR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0B028_9BURK ---RFRTEIARIEAASGGRLGVAILDTHDGVFY-GHREDERFPMCSTFKFLLAAHVLARVD -RKEERLDRRVAVRTVDLVAYSPATQPHADGEMSIAALCDASVTLSDNTAANLLLASAGGP -AGLTAYLRQLGDAHTRLDRNEPSLNTARPGDPRDTTTPAAMLGSMRKLVLGDALSPASRT -QLTRWLVDNKTGDARLRAGIPKGWKVGDKTGSGAYGTNNDIGVIWPSGRDPVLVTAYLTG -TVEPVATRERALAEVGKLVT--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G0Z390_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7E7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI0002CC593A ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMETTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. M2T2B2 TaxID=682998 RepID=A0A2U9SAX9_9PROT ----LAARMAALEGRTGGRLGVAMLDTGTGRLQ-GWRMDERFPMCSTFKFLLAAAVLKAVD -QGREKLDRRIPVTEADLVPYAPFAETRLNGTPTVAELCEATMTLSDNVAANLLLPGVGNP -AGLTAFLRGIGDGITRLDRNEPTLNSAIPGDPRDTTTPAAMARSMERLMVGEVLRPESRR -QLIDWMIANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPDNRPPLLVASYLTQ -TAKGFKQHDSIHAEVARAVAE-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0001BE674B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELGEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Pop5 TaxID=1223565 RepID=K0VP01_9RHIZ --dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-SYRGSEAFPMCSTFKALAAGFVLARVD -KGQESLDRRVTYGKEKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPEAMLDTLGNLTLGSILAETSCD -RLIAWLVASTTGKERLRAGLPEDWKVGDKTGTGPNGSLGDIAVIWPPDRSPIVAAVYIAE -ATASAKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium subtsugae TaxID=251747 RepID=UPI000640D036 ---SAAARLSALEADFGGRLGVCALDTASGAEL-GHRAGERFPFCSTFKAMLVGAVLARSA -KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKWLGGP -AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPHAQR -QLVEWLRGNTTGDEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPAVLTVFTTQ -AREDAKQRHQVVAAAARIAAD-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI00061C4462 ---SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E1771C ---SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A7ISS0_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGANERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Rahnella woolbedingensis TaxID=1510574 RepID=A0A419N222_9GAMM ---SIQQQLTALEKDSGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE -SNKALLDQHVALKKSDLVNYNPITEKHLNDGMTIGELAAAALQYSDNAAMNKLIEHLGGP -HKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAETQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PQKDAKSRRDVLASAAKIVTQGy ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0006581777 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=B6VB30_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Cobetia marina TaxID=28258 RepID=UPI0008662192 ------ANLQEIEQRVGARLGVTVLDTANGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD -ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP -VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL -TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE -SEAERAVRDAAIADVGRLLVS-- ->[subseq from] Beta-lactamase n=1 Tax=Dokdonella koreensis DS-123 TaxID=1300342 RepID=A0A161HIN5_9GAMM ------DRLAELERASGGRLGVAVLDTATGRSL-GWRDEERFAMCSTFKFLLAAAVLQRVD -RGELTLDRRLPIRKDDLIHHSPVTERHVGSHLAVADLCEATMTLSDNAAANLLLPLVGGP -AGLTATLRAWGDATTRLDRPEPHLNDVPPGDPRDTTTPREMAAHVQRLVLGDLLQPASRE -RLTGWLAGNRTGDHRLRAGLPKGWRVGDKTGSGP-GTTNDVAIVWPEGRAPFALACYLTG -SSLKDDGRNAILASVAREVAG-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C0BE023 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYKTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q2PXM9_ACIBA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPDNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=4 Tax=Leminorella grimontii TaxID=82981 RepID=A0A085HAX1_9GAMM ----IQQKLANLEKSAGGRLGVALIDTEDNSRV-LYRGDERFAMCSTSKVMAVAAVLKQSE -TDKGVLSKKIKIKKADLVNWNPITEKHVNSSMTLEELSAATLQYSDNVAMNKIIAHLGGP -NKVTAFARSIDDTTFRLDRTEPSLNTAIPGDERDTTTPLAMAESLRNLTLGNALGETQRA -QLVEWLKGNTTGGESIRAGLPKAWIVGDKTGSGDYGTTNDIAVIWPENRAPLILVTYFTQ -PKQDAKSRRDVLAAAAKIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Legionella rubrilucens TaxID=458 RepID=A0A0W0XXD6_9GAMM ---SLQQKLAALEASTGGRLGIAAINQANGMTI-QYHARQAFPLCSTSKAMGVAALLSRSM -RDKTLLQEKIHYSKQDLVVHSPETEKHLADGMTLAELCEATITQSDNAAINLILKKMGGP -KAVTAFARSIGDNQFRLDRFEPELNTAIPGDPRDTTTPKAMALSLQKLTTTDTLAAPERQ -LLIKWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTTNDIGVIWPPHCQPVTLAVYFTQ -PKVDATPNNDVIAAATRIVISAf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00101F16F7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLF--- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A6XFB8_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8JH97_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIHTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=UPI00102A6AAA ----FETAFKDLEKASGARLGVSVHDTGSGKRI-GYREKELFAMCSTFKFFAAAAILARVD -QKKEKLDRVIRYGKSDLVTYSPVTEKHVADGMTLSAICDAAITWSDNAAGNLMLDALGGS -QGMTDYARSLGDTISRLDRREPELNEAKPGDPRDTTTPAAMRENLEKTVLGTALSEPSRK -QLTDWLVGNKVGDKRLRAGLPKDWKVGDKTGTSDSGMANDVAVIWPPDRKPIVLTVYLYD -PKGTPDSRNLIHQKVARLVADH- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B40503D ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=B7FDE2_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=UPI000662E90F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSPAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q2WEB7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella sp. HMSC16A12 TaxID=1581108 RepID=UPI0008A1C68C ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter sp. CFNIH10 TaxID=1920110 RepID=A0A3Q8DCH8_9ENTR ---QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A381G8S3_CITAM ---QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter sp. MGH 55 TaxID=1439319 RepID=UPI0004A084BA ---QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium retamae TaxID=1300035 RepID=UPI0007C6D4E4 ----LIDEIRRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKMLAAAAILARVD -AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLAGIGGP -PGLTAFVRSLGDQVTRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALILGKALSAASRE -QLTAWLVANKTGDARLRAGFAKDWRIGDKTGTGARGTNNDVAVIWPPRKAPIVITAYLTG -ATVSAAQQNATLASVARAVS--- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum lipoferum TaxID=193 RepID=A0A5A9GFE3_AZOLI ---AFAARMTELEGRTGGRLGVAVLDSGTGRLH-GWRGDERFPMCSTFKFLLAAAVLKSVD -QGKDRLDRQIPVTKADLVPYAPFSEKRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGNP -AGLTVFLRRIGDRITRLDRNEPTLNTAIPGDPRDTTTPAAMVHSMERLLVGDVLRPDSRR -QLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTQ -TAEGFKQQDAIHAEVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=U5KKE2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWGIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B6FA355 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Proteus TaxID=583 RepID=A0A2J9LCP9_PROMI --nTIEEQLNTLEKYSQGRLGVALINTKDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDNSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIAKAAEIVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium retamae TaxID=1300035 RepID=A0A0R3MC94_9BRAD ----LIDEIRRLERESGGRLGVCVLDTATGARH-VHRGDERFPMCSTFKMLAAAAILARVD -AGKEQLTRRITFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLAGIGGP -PGLTAFVRSLGDQVTRLDRDEPSLNEALPDDPRDTTTPNAMASNLQALILGKALSAASRE -QLTAWLVANKTGDARLRAGFAKDWRIGDKTGTGARGTNNDVAVIWPPRKAPIVITAYLTG -ATVSAAQQNATLASVARAVS--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE83_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKNE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9R746_KLEPN ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGGSERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D6CD3A ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=W8E5Z0_ECOLX ---ETLVKVKDAEDQLGAPVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q8KSA6_ECOLX --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGGYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=U5U781_PSEAI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A/beta-lactamase class A CTX-M n=10 Tax=Bacteria TaxID=2 RepID=A0A4R2ZCR7_9GAMM ---SVQQQLTALEKESGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PEKDAKSRRDVLASAAKIVTQGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL84_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=C5IXH9_PROMI --nDVQQKLAALEKSSGGRLGVALINTADNTQT-LYRADERFAMCSTSKVMAVAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLVLVTYFTQ -SEPKAESRRDVLAAAARIVTDGy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI000B891C33 ---ATHREFAQLEKNFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKDDLVTYSPVTEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFKKLAGP -KGFEKALRQIGDRVTMADRFETELNEAIPGDIRDTSTPKALATDLKAFTVGNALPADKRK -ILTDWMRGNTTGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] TEM family class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0007DDBF91 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLGEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001144B8FD ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=209 Tax=root TaxID=1 RepID=Q7X574_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0003FE868C ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000797DC5A ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q6V3W5_ACIBA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000450B0DD ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6KB04_KLEOX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001330A9A1 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGNPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI0006E65094 ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=4 Tax=Enterobacterales TaxID=91347 RepID=Q7BP43_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI001374BC08 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDKRNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=A0A0G3SBL4_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=8 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A068F3Z2_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase OXY-1 n=13 Tax=Bacteria TaxID=2 RepID=BLO1_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI00042D3CCF ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASRRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2MJC2_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASRRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DCF298 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Escherichia coli TaxID=562 RepID=Q934D7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKLw ->[subseq from] Beta-lactamase n=1 Tax=mixed culture bacterium PE_gF3SD01_32 TaxID=663178 RepID=C8C169_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIDDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. NR 4-1 TaxID=1678028 RepID=A0A0K1JUJ2_9BURK ---TAEAQLAALEKAAGGRLGVAAWRTDSAKRI-GHRSEERFPLCSTFKAMLAAAVLARSA -NDEELLGKSVRYRADELVTYSPVTEKHVDDGMTVAALCAATLQYSDNSAANFLMRMMGGP -QALTAYMRSIGNPVFQLERWETELNTAIPGDTRDTANPASMARSLQALLLGDALPAPQRR -QLDTWMRGNTTGDQRIRAGVPAGWSVADKTGAGAHGTVNDIGIAYPPSGAPIVIAVYYTR -EQKDAPTNQDIIAAATRIVM--- ->[subseq from] class A beta-lactamase n=1 Tax=Cobetia sp. MM1IDA2H-1 TaxID=1268241 RepID=UPI000985AC0E ------ANLQEIEQRVGARLGVTVLDTADGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD -ARQESLSRKVEIRPADLVSYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP -VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL -TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE -SEAERAVRDAAIADVGRLLVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000757F666 -----ASSLAELERAAGGRLGVHVLDTATGRRV-RHRADERFPFCSTFKAILIAAVLAESV -ARPALFTQRVTYRQADLLEWSPVTEKHVDTGMTVSELCEATAQYSDNAAANLLMKLLGGP -AAVTAFARSIGDDTFRLDRWEPELNTALPGDARDTTTPAAMAASLRALALGDALPAPQRA -QFAQWLRGNKTGDKRIRAGVPTGWQVGDKTGTGDYGTTNDIGVLG-----PIVLTVYYTQ -ARADAKRKDDVIAAATRIAI--- ->[subseq from] Uncharacterized protein n=1 Tax=Eimeria acervulina TaxID=5801 RepID=U6GQT8_EIMAC -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. ZXX171 TaxID=2695858 RepID=UPI001370DB43 -----IDTVKQVENRLQARVGVAVSDLGGDRTW-RHNADQRFPLASTFKVLACGALLHKVD -AGDESLERVIHFKKQDLVTYSPETQQHLDSGMTLGALCEAAITQSDNTAANLLLDRLDGP -AGLTRFLRGIGDDTTRLDRRETELNEGTPGDPRDTTTPDAMLATLRVLVFGDVLSESSRQ -QLLQWMKDDKIADALLRAGIPDDWTIGDKTGAGGHGSRAIIAVMWPPQQEPVLAAIYITE -TDASMDQRNAAIAEIGRALA--- ->[subseq from] TEM family class A beta-lactamase n=2 Tax=cellular organisms TaxID=131567 RepID=UPI0007AE5081 ---ETLVKVKDAEDQLGARVGYIELDINSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=A0A649UHK0_KLEAE ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. RV1423 TaxID=1443993 RepID=UPI0004B0392D ----VVSRLAKLEAGVNGRLGVEILDTASGKHW-GYRADERFPMCSTFKFLAASAVLKRVD -AGAEQLDRRIVYGEDVLVSYSPTTAKHVGGDLSLAQLCEAAITLSDNTAANLILRSIGGL -EPFNDFVASLGDGVTRLSRFETELNSAIPGDPRDTTTPAAMTANLHKVLLGDVLSPASRR -QITAWMAANKTGDQRLRAGMAPGWKVGDKTGSGDHGTTNTVAIIWPPQGKPLLASIYLTE -TKAPAERRNAVLADVGKLIV--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F4ZCJ5_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLREIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase SHV-13 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA13_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010134DC3 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVYDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI00070C3E4B -haKIQQKLMALEKESGGRLGVTLINTADNSQI-HYRADERFPMCSTSKVMAASALLKKSE -TQKGLMDERIHFKKSDLVTWSPITEKKLQEGMTWAELSAATLQYSDNTAMNLILTQLGSP -AKLTEFARSIGDKSFRLDRPEPELNTAIPGDERDTSTPQAMAESLQNLTLGDALAKSQRA -QLVGWLKGNTTGAASIRAGLPATWQVGDKTGAGEYGTTNDIAVIWPDNHAPLILVTYFTQ -PVKDAQSRREILAEAAKIAVSPf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM37_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTATPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI00065A8599 ---SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLARGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATQIILS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella senftenberg TaxID=28150 RepID=U6BP97_SALSE ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAS----- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q8RJ46_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Photorhabdus asymbiotica TaxID=291112 RepID=B6VKV8_PHOAA ---SLYKQLAELENSTKGRLGVTLINTANGQEI-QYRGDERFPFCSTFKLIVVAAVLHKSM -SQSELLAKHINYSETDLLSYAPIARKHLNQGMSITQLCAATLQYSDNTAVNLLIKELGGV -EAVNHFTQSLGDHTFRLDRWEPDLNSAIPDDHRDTTTPAAMAASVKKIVFGEVLAELQRD -LLIDWLKGNTTGDASIRAGVPTGWVVGDKTGGGDYGTTNDVAILWPPKGAPVILAVYFTQ -PQKDAESRRDVLASATRLVMEH- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBB3D0 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSPRSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Caballeronia terrestris TaxID=1226301 RepID=A0A158HLE8_9BURK ---SAASRLKALEDASKGRLGVSALNTADGSRI-DYRADERFAFCSTFKVVLSSAILTRSA -RDEGLLARRIRYGQSDIVANSPVTSKHVADGMTVGELCAAALQYSDNAAANLLIRLHGEP -ADVTAYARSIGDTEFRLDRMETELNTAIPGDPRDTTTPAAMALTLQRLALGNALGVAQRD -QLQTWMRANTTGDKRIRAGVPRDWQVADKTGTGDYGTSNDIAVLWPPAKPPIVLVIYFTQ -REQDAKARDDVLASAARIVAEKf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0008464001 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Nissabacter sp. SGAir0207 TaxID=2126321 RepID=A0A4P8SMN7_9GAMM -hsQLQQQLAELEQRSGGRLGVALIDTADNWQF-SYRGAERFPMCSTSKVMVAGKLLKQSE -HEPGLLGQRVDIHDSDLVNYNPITQQHVGGSMSWGELSAAALQYSDNTAMNKLLGGLGGP -QHITAFARTLGDSQFRLDRTEPTLNTALPGDPRDTTTPVAMAESLRKLALGSALAAPQRE -QLVVWMKGNTTGKASIRAGLPAEWQTADKTGSGDYGTTNDIAVIWPKNHAPLVLVTYFTQ -PLPDAAGNKAVLADAARIVTQGy ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2S1JDQ1_ECOLX ---NIQQQLSELEKNSGGRLGVALIDTADNSQI-LYRGDERFPMCSTSKVMAVSALLKQSE -MDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAELSAAAIQYSDNTAMNKILEHLGGP -AKVTEYARTIGDKTFRLDRTEPTLNTAIPSDKRDTTSPLAMAKSLQTLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPATWVVGDKTGIGDYGTTNDIAVIWPANHAPLVLVTYFTQ -PQQNAEARKDVLAAAAKIVTE-- ->[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KTY4_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFATCITSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTN-- ->[subseq from] PenA family class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000841FF7C ------TSFDALERAAGGRLGVCAIDTATGRRV-QHRADERFPFCSTFKAMLIAAVLAQSV -ARPALLAQRVTYRQADLVRYSPVTEQHVGAGMTVGELCEATAQYSDNSAANLLMKVLGGP -SAVTAFARTIGDDTFRLDRWETELNTALPGDTRDTTTPAAMAVSLRVLALGDAL----RA -QFVAWLRGNKTGDKRIRAGVPAGWQVGDKTGTGDYGTTNDVGVLWPPARGPVALAVYYTQ -ARADALAKDDVIAAATRIAI--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI00082801BC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERKRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX88_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEVLPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus bovis TaxID=1616788 RepID=A0A172ZME5_9BACL ---SLASRFRALEQQHQARLGVYAIDTGTGKVV-AYRHNERFAFASTYKALAAAAVLQQNS ---IADLDRVITYSADDLVEYSPVTEKHVDTGMTLREICEAAIQYSDNTAGNILFQELNGP -AGFQQTLRQLEDRTTRSERIEPELNAAVPGDARDTSTPRALVRDLRLFTTGKVLSQDKRQ -LLAEWMKGNTTGNDLIRAAVPKGWVVGDKTGSASYGTRNDIAVVWPPGRAPIIIAVLTGH -TDKEAKADNELVAKAAKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=Q5I5D9_SALER ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPIDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kerstersia gyiorum TaxID=206506 RepID=A0A649UIV6_9BURK ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase n=4 Tax=root TaxID=1 RepID=A0A4U9LD97_ECOLX -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E05418 ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL62_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAS----- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. MOS003 TaxID=2133946 RepID=A0A2T2PZ56_9BRAD ------EAIKQLELKSGGRLGVSVLDTTTRVPI-HHKGDERFPMCSTFKVLASAAILKAAS -SKLETLERRVRIDQADLVENSPITREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTSFARSLGDDITRLDRTETELNEATPGDPRDTTTPNAMAANYRRLLLGDVLPPEGRD -QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTTNDVAIVWPPKRSPLIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E490C6 ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDASIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] SED family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00128D753B ---QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKWRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sonorensis L12 TaxID=1274524 RepID=M5PIH6_9BACI ---ALNDAFAKLEDQFDARLGVYALDTGTNQTI-AYRADERFAYASTHKALAVGALLQQKS ---ITDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP -DGFKKSLRKIGDKVTNPERFEPELNEVKPGETHDTSTPKALATSLKAFTIGDALPKEKRM -MLIDWLKRNTTGDALIRAGVPKGWEVGDKTGAGSYGTRNDIAVIWPPKGDPIVLAILSSR -DQKDAEYDDKLIAQAAKEVID-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter hydrocarbonoclasticus TaxID=2743 RepID=A0A1M2V1K3_MARHY -hnSLIKTVEKVADDLEAHVGFAAYDMESGQRW-EYHADQRFAMSSTFKTLACAALLHQVD -RGQVNLGRKVHVSESDLVTYSPITEKHTGGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EAVTSFARDLGDDVTRLDRWETELNEALPGDTRDTTTPNAMVRNLQTLLLGDALSEPSRE -QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ -TEASFEERNAAIAEIGEAIV--- ->[subseq from] Beta-lactamase n=2 Tax=Caballeronia udeis TaxID=1232866 RepID=A0A158HC11_9BURK -----QDQLKQLESSAGGRLGVAALNTADGKLV-NYRADERFPLCSTFKLMLVSAVLEQSE -SQKGLLERRIHYARSELLSWAPITKKQVATGMTVAELCAATLQYSDNTAANLLMKLVGGP -ETVTAYARSIGDNQFHLDRREPDLNSAIPGDPRDTSTPAAMAHSLQRVTLGDALGASQRS -QLQTWLLGNTTGAGKIAAAMPAHWMIGDKTGSGDYGTTNDIGVIWPPGKPPIVLAIYLTQ -REQDAKARDDVVASAARIVVAAf ->[subseq from] SHV-12 n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A6C0L4K1_KLEOX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C6C884B ---ETLVKVKDAKDQLGKRVGYIELDLASGKILvSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTAASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Uncharacterized protein n=2 Tax=cellular organisms TaxID=131567 RepID=A0A2A2K9F8_9BILA ----LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAILAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -SGLTAFTRSLGDPRFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQDWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWIVVVFSRG -TKADAPWNSETIAAATRVVVEAw ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q4JL90_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A0A0CVB0_PHOLU ---SLHKQLAELENSTKGRLGVMLINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM -SQPELLAKHIHYRESDLLSYAPITHKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL -EAVNRFTQGIDDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVLGASQRE -QLIVWLKGNTTGDASIRAGAPAGWIVGDKTGAGDYGTTNDVAVLWPPKGAPVVLAVYFTQ -PQQDAESRRDVLAAATRLVMAH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD2B591 --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=A0A3W2F3P6_SALER ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTVELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. H4 TaxID=2035449 RepID=UPI000D0FF826 --dDVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005FD0364 ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBB6EA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Kluyvera cryocrescens TaxID=580 RepID=UPI00068B26B2 ---SVEQKLAALEKASGGRLGVALIDTADDSQM-LYRADERFAMCSTSKVMAAAGVLKKSE -TEHNLLNKRVKINKSDLTNYNPIAEKHVGGSMSLSELSAAALQYSDNVAMNKLIEQLGGP -DGVTAFARQVGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALGDTQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLVLVTYFTQ -TQPKAESRRDVLASAAKIVTE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B5E53 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=Q5QQ30_KLEPN ---ETLVKVKPAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B4203F2 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMEDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3Q9HH75_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAS----- ->[subseq from] Class A beta-lactamase SHV-224 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTK0_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAALARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0012B9D1BB ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHPQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. ZN5 TaxID=2697019 RepID=UPI0013E12865 --nTIEEQLSTLEKYSQGRLGVALINTEDNAQI-TYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIAKAAEIVTK-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00051AABC2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPLTSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P9E6B0_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Cobetia marina TaxID=28258 RepID=A0A4Y4GNA4_COBMA ------ANLQEIEQRVGARLGVTVLDTADGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD -ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP -VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL -TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE -SEAERTVRDAAIADVGRLLVS-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007DD69E6 ---ETLVKVKDAEDQLGAREGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Leminorella richardii TaxID=158841 RepID=A0A2X4XUF8_9GAMM --dALQQKLADLEKSTGGRLGVALINTADNSQI-VYRGDERFAMCSTSKVMAAAAVLKQSE -TDSRVLSKKVAITKADLTNWSPIAKKHLGAGMTLAEMSAATLQYSDNTAMNKILTHLGGP -EKVTAFARSIGDTTYRLDRTEPALNSALPGDPRDTTTPLAMAKSLRSLTLDNALGETQRA -QLVEWMKGNTTGDASIRAGLPKNWIVGDKTGSGDYGTTNDIAVIWPENRAPLILVTYFTQ -PQQNAKARRDVLASAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A2W5EE87_AZOBR ----LPARFAAIERRVGGRLGVAVLDTATGQRA-GHRETEPFPLTSTFKLLAAAAVLARAD -AGQARLGQRIHYGREKLVTYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQLGGP -AGLTAWLRSIGDEVTRLDRWETALNEAVPGDPRDTTSPAAMLASLRKVTLGEVLSDEGRA -RLTGWLRANRTGDQRLRAGLPEGWQAGDKTGAGERGTNNDVGLLWPPGGAPILVAAYSTG -SAADGAARDAALAEVATAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q9F0F5_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLHCWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. UYPR1.413 TaxID=1080179 RepID=UPI000490347F ---AFEKQLAQIEAQVGGRLGVAILDTASGKQH-GWRMNERFPMCSTFKVLLASAVLTRKD -QGKEELGRKVVYAKDVVVANSPVSGPRAGGDMTVSELCEAAITRSDNTAANLLLESIGGP -AALTAFVRGMGDKVTRLDRNEPTLNEALDGDPRDTTTPAAMLADLRALLLGEHLSAASRE -QLTAWLVANKTGDARLRAGLPKDARVGDKTGTGERGTSNDIAIVWPAGRPPILVTVYLTG -ATASAAQRDAAIAKVGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. CFH 70021 TaxID=2202148 RepID=A0A2S2CMP3_9PROT ---ALRDAMAALERRSGGRLGVAVLDTGSGRRF-DWRGGERFPMCSTFKFLLAAAVLKRVD -QGRDSLERRIPVTAADLVPYAPFAEGRVNGTPTVAELCEAAVTLSDNVAANLLLSAVGDP -AGLTAFVRTLGDTHSRLDRNEPELNSSIPGDPRDTTTPNAMVHSMGRLMLGDALRPASRD -QLIAWMVANRTGDKRLRAGLPQGWRVGDKTGTGN-GSFNDIAIVWPAGKPPLLVASYLTQ -TPKGFAQGDAVHADVAKAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL19 TaxID=2603896 RepID=A0A5C8UFV9_9RHIZ --rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAVLARVD -RGEDGLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLRTMGGP -AGLTGHIRGFGDATTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG -ARTSSEARSATIASVARAVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Herbaspirillum hiltneri TaxID=341045 RepID=A0A561JZ53_9BURK ----VVSRLAKLEASVAGRLGVEILDSGTGRRW-GYRADERFPMCSTFKFPAASAVLRRVD -TGAEQLDRRIVYGEDVLVNYSPTTSKHVGGDLSLAQLCEAAITLSDNTAANLILHSLGGL -GPFNKFVRSLGDDTTRLDRFETELNTSIPGDPRDTTTPTAMTGNLQKILLGDALSAASRR -QITAWMLANKTGDRRVRAGMQPGWKVGDKTGSGDYGTTNTVAIIWPPQGAPLLASIYLTE -TRAPEEQRNAVLAEVGKLIV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 103mf TaxID=1761751 RepID=A0A1I6TEM7_9BACI ---ATHREFAQLEKNFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKDDLVTYSPVTEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFKKLAGP -KGFEKALRQIGDRVTMADRFETELNEAIPGDIRDTSTPKALATDLKAFTVGNALPADKRK -ILTDWMRGNTTGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93MS4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKLw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE68_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDEAFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CDAD3AB -------KVKDVEDQVGAGVGYIEVDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1I6W9Y5_9BACI ---ATHRELVQLEKKFDARIGVYAIDTGTNRTV-AYRPNERFAYASTFKALAAGAVLQQNS ---IDKLDEVITYTKDDLVTYSPITEKHVDTGMTLGEIAEAAICYSDNTAGNLLLKKLNGP -NGFEKALRQIGDRVTMADRFEPDLNEATPGDIRDTSTPKALATNLKAFTIGNALPTDKRK -ILTDWMRGNTTGDQLIRAGVPKGWEVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYNNELIAQAAKITIN-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C7F41E5 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHPADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A193CHV5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira xianhensis MCCC 1A02616 TaxID=1177929 RepID=A0A367UCN7_9PROT ---RLMDAIHAVETRLGARVGVSILNVENGREW-QYREDERFPLTSTFKLLACAAVLHKVD -FGTETLDRRITYGAEDLVPYSPITEKHVDGGMTIGELCEATLHLSDNTAANLILDALGGP -GKLTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRALLAYLLLGDALSPESRQ -LLEDWLMGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIAAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] Beta-lactamase n=1 Tax=Blastochloris viridis TaxID=1079 RepID=A0A0H5BBF8_BLAVI ---ATERALADLERRFGGRLGVAILDTGSARRA-SHRGSERFALCSTFKVLAAAVVLARVE -RGDDSLDRRILYRRDDLVPYSPVTERRLADGMTLGELCEATMTLSDNTAANLLLDSFGGP -AAVTAMLRGLGDGATRLDRREPALNDVPPGEERDTTTPQAMGDTLLRLVVGNALAPASRH -RLIEWLVNCKTGDQRLRAGVPAAWRVGDKTGSGPRGEANDVAVMWPPGRAPMVVTAYYVN -PAGSADARNAVLAEVGRLVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia nodosa TaxID=392320 RepID=UPI00048A18AF ---TLEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMHERFPMCSTFKVLLASAVLTRKD -HGKEDLARKVVYTPAQVVSYSPVSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP -SAITTFARSIGDPVTRLDRNETTLNEAIPGDPRDTTTPAAMVANLRELLLGERLSAASRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDRGTANDVAIVWPTGRAPILVTTYLTG -ATASSAQRDAAIARVGVWVA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C5C1Y7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYTPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Curvibacter gracilis TaxID=230310 RepID=UPI000488E180 ------GQWQALERESQGRLGVAVFDTQSGAWL-GHRLDERFAMCSTFKWLAAAQVLRRVD -QGLERLDRRIEFGREALLPWSPVTEKHAGGAMTVGELCHAAITVSDNAAANLLLRSFGGP -EGLTRFARQLGDPVTRLDRWEPELNEATPGDPRDTSSPRAMVELLRQAVLGPALSAGSRQ -QLAQWLQATQTNLKRLAADLPAAWRVGSKTGTGAHGSTNDVGLYWPPDRGPIVVAVFLTE -SKASLEAREAVIAQVARRVH--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL87_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLIKH- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00098385B7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNSQIAEIGASLI--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL80_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLIKH- ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q6UK84_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGEHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. URHB0020 TaxID=1380385 RepID=UPI000482AF5E ---ELSQRFAKIEKTSGARLGVLVLDTGSGVRA-GHREDERFPMCSTFKFLAAAAILARVD -QQRERLDRRVVFHERELVDNSPVTEKHVGGAMTVAALCEAAITRSDNTAGNLMLASIGGP -AGLTRYTRSLGDKQSRLDRTETALNEARPGDPRDTTTPAAMLGDMQKILLGAALSLPSRA -QLLRWLDANQTGGQRLRAGVPADWVVGDKTGSGDQGTANVIAILRPPGRAPILAAVYLTE -STASMEFRNATIASVGAAFAK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A221SNF6_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQKDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGA------ ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A7LLU6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNRAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9R770_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG -GQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RIY3_9BACT ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sophoriradicis TaxID=1535245 RepID=UPI000BBD5FBC ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. IE4771 TaxID=1301032 RepID=A0A060HY47_9RHIZ ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. WYCCWR10014 TaxID=1825933 RepID=A0A198YLE4_9RHIZ ---NIDRRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVNYGKDKLVDYSPISEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQTGSLGDIAVIWPPDRGPIVAAVYISQ -ATVPAKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CB00B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKXAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B958953 ------EQIKQSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9J1_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDGQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia plantarii TaxID=41899 RepID=UPI0006D8AC7A ------RQLAALDGSFDGRIGVAALDTGSGARL-LHRADERFAFCSTFKTILVSAVLTRAA -GDPRLLSSVIRYRAQDLVRYSPVSEKHVDTGMSVAGLCAAALQYSDNSAANLLIRMVGGP -AAVTAYARSIGDRRFRLDRIETELNDAVPGDERDTTTPAAMLDTLRRVTLGDALDASGRA -RLISWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLVVYTTR -DRKDAEYDNAAIASAARIVTAAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q93K44_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082D4C0 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKSGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A9A1_SHISO -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q71LW4_KLEPN ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADRVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Ghvi TaxID=1855319 RepID=A0A1I5K9T4_9BRAD ------DAIKQLELKSGGRLGVSVLDTNTGVPI-HHRGDERFPMCSTFKVLASAAVLKAAG -SKLEGLERRVRIEQADLVEYSPVTGKHVGGEMSLRELCEAAITMSDNTAGNALLKNIGDP -AGLTSFARSLGDDITRLDRIETELNEATPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD -QLGKWLIANKTGDTRLRAGLPHGWRVGDKTGAGEHGTTNDVAIVWPPERSPLIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A218MJA3_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGSLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT58W TaxID=2654254 RepID=UPI001264F619 ----PQQQLAALEQAAGGRLGISAVNARTGATV-AHRADERFPMCSTFKAMLAAAILARQA -GDATLLAQRISYQKSELVTYSPITEKHLADGMTVAELCAATVQYSDNSAANFLMKLLGGP -QAVTAFARSIGNDVFQLERWETELNSAIPGEVRDTTSPTAMTHSLQQLLLGEALPASQRQ -QLESWMRGNTTGDQRIRAGLPAGWSAADKTGSGAYGTVNDIGVAWSPDGTPLVIAIYYTR -EVKNAPTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium gallicum TaxID=56730 RepID=A0A1L5NG50_9RHIZ --dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP -KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE -KLIEWMLANTTGDARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE -ATAPVKELNLVFAEVAKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F8SQ10_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AALTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPHNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPP4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLSLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium subtsugae TaxID=251747 RepID=UPI0006416144 ---SAAARLAALEADFGGRLGVCALDTASGAEL-GHRAGERFPFCSTFKAMLVGAVLARSA -KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKLLGGP -AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPHAQR -QLVEWLRGNTTGAEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPAVLTVFTTQ -ALEDAKQRHQVVAAAARIAAD-- ->[subseq from] Beta-lactamase n=2 Tax=Proteus vulgaris TaxID=585 RepID=Q52615_PROVU --nTIEEQLNTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDNSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQNAKYRKDIIAKAAEIVTK-- ->[subseq from] class A beta-lactamase n=1 Tax=Verrucomicrobium sp. BvORR034 TaxID=1396418 RepID=UPI000679BC29 -----VSKLEGIEGQDGARLGVYALDLESGMEI-KHRAEERFPVCSTFKVILTSAILKQSV -QDAGLMTRRISYAKHELVTYSPVTEKHVEDGMTVEALCAAAMQYSDNTAANLLMKILGGP -GAVTAYARSIGDTQFRLDRWETELNTALPGDPRDTSTPAAMGHSLQKLAWGDGLPEAQRA -KLVEWMLGNTTGDKRIRVAVPPDWKVGDKTGSGDYGTANDIAILWPPGRKPIVLAIYHTQ -KAADAKWQNEAIAAAARVVLEAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A142FK11_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMSATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=UPI000F66FBA4 ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRMDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=C4NZW3_SALTM ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLEREIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=Q6PW40_CITKO ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A177262 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=I3WA87_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Escherichia coli TaxID=562 RepID=A0A2H4FYM3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B8CDA28 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPVGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Salmonella derby TaxID=28144 RepID=Q4GX46_SALDE ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDCWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A0B4UA24_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=Q3HLW6_SHIFL ---ETLVKVKDAEDQLGARVGYIELDLNGGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root434 TaxID=1736536 RepID=A0A0Q7HDK9_9BURK ---SAEAQLAELERASGGRLGVAGFHTGSGARI-QHRAHERFPLCSTFKLMLAAAVLERSA -KDVSLLARHIGYGKADLVSWSPITEKHVADGMTVAELCAATVQYSDNGAANLLLKMLGGP -ATVTAFARGIGDQAFRLDRTEPELNTAIPGDLRDTTTPAAMSDSVQRLALGDALGTAQRE -QLKDWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPVVLSVYLTF -PQKDAKGRNDVIASATRIVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Cobetia marina TaxID=28258 RepID=A0A4U1M2X5_COBMA ------ANLQEIEQRVGARLGVTVLDTADGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD -ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP -VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL -TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE -SEAERTVRDAAIADVGRLLVS-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6WSQ7_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTGKRGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A3FFR3_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQHLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0001FD28D0 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVEYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. 54 TaxID=2035212 RepID=A0A2G6X6R7_9BURK ---DAEAQLAELERACGGRLGVAGFHTGSGTRL-QHRAHERFPLCSTFKLMLAAAVLERSA -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMRDWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL92_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella spallanzanii TaxID=2587528 RepID=A0A5P1KAR8_9ENTR --nAIQQKLADLEKNTGGRLGVALIDTTDNSQV-LYRGDEHFAMCSTGKVMAAAAVLKQSE -ADNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP -EKVTAFAHSIGDVTFRLDRTEPTLNTAIPGDERDTTTPLAMAESLHKLTLGYALGEQQRA -QLVTWLKGNTTGGQSISAGLPAGWVVGDKTGAGEYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=B2LUM6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000B49405B ---AIHQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGEQSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8VP57_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDKQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGGRGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. PMC12 TaxID=2126319 RepID=A0A2P1V6Y4_9BURK ---SAEAQLAELERSCGGRLGVVAFNTDSGARL-QHRAHERFPFCSTFKLMLAATVLERSA -KDPSLLARRISYGKADIIPNSPVTEKHVSDGMTVAALCAATIQYSDNAAANLLMKMLGGP -ADVTAFARTIGDQVFRLDRWETELNTAIPGDLRDTTTPAAMADSVQRLVLGDALAGAQRS -QLQTWLLGNTTSAERFMAAVPPGWKVGDKTGAGSYGTNNDVGVMWPPAGAPLVVAVYLTF -PDKDAKNRNDVVAAAARIAVN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=H6D900_9BACT -----LLKVKDAEDQLGARVGYIELDLNSNKILeSFRPEERFPMMSTFKVLLCGAVLSRAD -AKQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium pachyrhizi TaxID=280333 RepID=UPI00128EC656 ------------------RLGVAVLDMETGLRA-SRRGDERFPMCSTFKAMASAAVLHRVD -RGETSLEQRVQIEAKDILAYAPVTKGRVGSAMTLSELCAAAITLSDNTAANLLLREIGGP -AGFTSFFRTIGDNVSRLDRWEVELNEAVPGDPRDTTSPVAMLKDLQRVLLGDVLSAASRQ -KLVDWMVANKTGDARLRAGVPRDWRVGDKTGTGERGTYNDIGVFWPPGRKPIVVTVYLTG -ASAPMETCNEVIANVARAVAN-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000669003D ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella spallanzanii TaxID=2587528 RepID=A0A5P1KAV5_9ENTR --nAIQQKLADLEKSTGGRLGVALIDTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNKDVVNKRLEIKASDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP -EKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PLQDAKSRKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Luteimonas sp. LNNU 24178 TaxID=2605430 RepID=UPI0011F04262 -----APALAELERDSGGRLGVAVLDSGSGQQA-GRHADERFPMCSTFKFLLAAAVLQQVD -RGRERLDRNVPIAESDLVPHSPQTEKHVGAEMRVGDLCRATMIRSDNAAANLLLRTLGGP -AGLTRFVRELGDPHTRLDRWEPELNSAVPGDPRDTTTPAAMARNLQRLLLGDVLHDASRA -LLTGWLVDNRTGDARLRAGLPKRWRVGDKTGTSILGTANDIAIVWPPGRSPLLITCYLTG -AAPDIGAMDAVHTAIARAVAATy ->[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=D2D0D6_RAOTE -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGT -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLHNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea TaxID=53335 RepID=UPI00067C4E8C ----LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE -TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP -HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALGPAQRQ -QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -TDKHAASRKDVLASAAKIIASGy ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8GNS6_KLEOX --nAIQQKLADLEKSTGGRLGVALIDTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNKDVVNKRLEIKASDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP -EKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PLQDAKSRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A7P2_SHISO -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUL0_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCTAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q9RMS2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea stewartii TaxID=66269 RepID=UPI00068CC1D7 ----LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE -TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP -HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALAPAQRQ -QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -TDKHAASRKDVLASAAKIIASGy ->[subseq from] Beta-lactamase n=1 Tax=Pantoea sp. PNA 03-3 TaxID=2135460 RepID=A0A2V3QGU9_9GAMM ----LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE -TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP -HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALAPAQRQ -QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -TDKHAASRKDVLASAAKIIASGy ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter sp. JT3 TaxID=1451265 RepID=UPI0005C523EE ---QVQEKLTALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6GWS9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E90A47 ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRYVLASATKIILS-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2F4_9BACT ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q09Q13_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2B887D ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSQALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALA9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRXD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase n=1 Tax=bacterium RRLBTTh23 TaxID=342578 RepID=Q3S2X1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMEERNRQIAEIGLSLIKHw ->[subseq from] TEM family class A beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=UPI000DE5E0F6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00004C2C83 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVAASPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXQ3_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLAPRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGGRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N2H6_KLEPN ------EQIKQSESQLSGRVGMIEMDQASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter amalonaticus Y19 TaxID=1261127 RepID=M1K0S5_CITAM --tQIQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKAMVAAAVLKQSE -TQHDILQQKMAIKKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT -GNVTAFARSIGDTTFRLDRTEPELNTAIPGDERDTTTPLAMAKSLHKLTLGDALADTQRA -QLVAWLKGNTTGGQSIRAGLPENWVVGDKTGGGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PQQDAKGRKDVLAAAAKIVTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea stewartii TaxID=66269 RepID=UPI0006D0552F ----LAQPVRQLEHAAGGRLGVAAIDTGDGSVF-TYRGNERFPLCSTSKVFTVAAILKKAE -TAQGLLNENIAIRHADLVNYNPVTEKQVGGTMTVAELSAAALQYSDNAAMNKLLTHLGGP -HAVTAFARSIGDNTFRLDRTEPTLNTAIPGDTRDTTSPTAMAQSLQKLVLGTALAPAQRQ -QLADWMKGNTTGTYSIRAGLPADWVVADKTGSGDYGTTNDIAVIWPPHHAPLVLVTYYTQ -TDKHAASRKDVLASAAKIIASGy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013BB1053 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZFW7_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKXLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAINKLIAQLGGP -GGVTAFARAIGDETFXLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRR-------------- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8RSU7_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115BCABF ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQHLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T607_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTPMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI00119F37F9 -----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPATQRE -QLTQWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ -REKDAKPRRDVLAAATKIVL--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6A2TGG8_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAAPIEHw ->[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A2V4T430_9PSED ------ARLKQLEGSFAGRLGVVALNTGNGEVL-SYRGEERFPLCSTFKAMLAAAILQRSS -LTPGLLQERIRYQKSDLVSYSPISEQHLQDGMTVAELCAATVQYSDNGAANLLMKLLDGP -EGVTTFARSIGDHHFRLERWETELNTAIPGDLRDTTTPLAMVHSLHKLVLGEALPAPQRQ -QLQDWLRGNTTGGTRIRAGVPATWQVGDKTGTGDYGTSNDVAVLWPPGKAPVVLALYLTQ -DAKDASPRNETLVAATRIVVD-- ->[subseq from] Extended spectrum beta-lactamase CTX-M n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060L031_9BACT ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCNTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPCDTTSPRAMAQTLRNLTLGKALGDSQRA -QLATWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLAPAAKIVTD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Serratia sp. Leaf51 TaxID=1736224 RepID=A0A0Q4MHQ4_9GAMM --kAVQQKLAELEKSTGGRLGVAMIDTASNTQT-LYRADERFAMCSTSKVMAASGILKASE -TDKNLLNKHVDIKKSDLVNYNPITEKHLDSGMTLGELGAAAIQYSDNVAMNKLIAHLGGP -AKVTQFARSLGDETFRLDRTEPSLNTAIPGDKRDTTSPLAMAESLRKLTLGNALAEPQRA -QLVEWLKGNTTGAASIRAGLPATWQVGDKTGSGDYGTTNDIAVIWPDNHAPLILVTYFTQ -PQQDAKARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Ewingella sp. SMO-1 TaxID=1332052 RepID=R4V074_9GAMM --kAVQQKLADLEKSTGGRLGVAMINTADNSQT-VYRGEERFAMCSTSKVMAASAYLKASE -QDKNLLNKHVDIKKSDLVNYNPITEKHLDTGMTLGELGAAAIEYSDNVAMNKLIAQLGGP -AKVTQFARSIGDETFRLDRTEPTLNTAIPGDKRDTTSPLAMAQSLRKLALGDALAEPQRA -QLVAWLKGNTTGAASIRAGLPASWTVGDKTGSGDYGTTNDIAVVWPDNHAPLILVTYFTQ -PQQDAKARKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FEE35 ------EAIEQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG -SKPEALERRVRIEQADLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTSFARSLGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD -QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium leguminosarum TaxID=384 RepID=Q1MJL1_RHIL3 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 TaxID=484021 RepID=A0A4P1LYI7_KLEPN ------EQIKQRESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTALLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A5Q3LGS1_RHIML --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0007D6ECB0 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI91_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNLQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A3E1SYG1_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPANWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5R1MD38_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGA------ ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia canariae TaxID=2607663 RepID=UPI001318F282 ---TLDKQLAELERGANGRLGIAMINTANGTKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -SQPNLLDKHINYHESDLLSYAPITRKNLAHGMTVAQLCAATVQYSDNTAANLLIKELGGV -EAVNQFARSIGDQMFRLDRWEPDLNTAVPNDPRDTTTPAAMAMSMNKLVLGDALLPAQRN -QLAVWLKGNTTGDATIRAGAPKDWVVGDKTGSGDYGTTNDIAVLWPTQGAPVVLVVYFTQ -REKDAKPRHDVLASATKIML--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium amphicarpaeae TaxID=1404768 RepID=A0A2U8PT95_9BRAD ---SLIEAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLASAAILKAAG -SKLEALERRVRIEQADLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTSFARSLGDDITRLDRTETELNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD -QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI000471B3F0 --dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGTLGDIAVIWPPDRGPIVAAVYIAE -ATAPVTELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. F16(2018) TaxID=2093746 RepID=UPI001119AF78 ----LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQAWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -AKADAPWNSETIAAATRVVVDAw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A851_SHISO -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASL---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=R4HET6_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium valentinum TaxID=1518501 RepID=A0A0R3LV23_9BRAD ---RLIGEIKRLESESGGRLGVCVLETATGTRH-VHRGDERFPMCSTFKALAAAAILARVD -AGNEQLTRRITFDASALVVNSPVTEKRVGGDMTVAEICDAAVTRSDNTAGNLLLAGIGGP -SGLTAFARSLGDEVTRLDRDEPSLNEALPGDPRDTTTPNAMASNLQALILGKALSAASRE -QLTAWLIANKTGDTRLRAGFAKGWRVGDKTGTGGRGTNNHVAVVWPPSAAPMVIAVYLTG -ATVSFEQQNAIVASVARAVS--- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A2W7KNE3_9PSED ----LRKALQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQAWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -AKADAPWNSETIAAATRVVVDAw ->[subseq from] class A beta-lactamase n=1 Tax=Streptococcus pyogenes TaxID=1314 RepID=UPI0011E6A449 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKQLTDGMTVRELCSAAITMSDNTAANLLLTTIGGT -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001031C303 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISL-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI000665E6E8 ---AIQQKLADLEKRSGGRLGIALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F0293DD -----LQRLIQLETTFAGRLGVVAINTGNGDVL-SYRGDEAFPLCSTFKAMLAAAILQRSV -LTPGLLEKRITYRKSDLVTYSPISEKHVQDGMTVAELCAATVQYSDNSAANLLLTLLDGP -EGLTTFARSIGDQHFRLERWETELNSAIPGDLRDTTTPLAMARSLQRLVIGDALPHMQRE -QLQAWLRGNTTGATRIRAGVPAAWQVGDKTGTGDYGTTNDVAVLWPPGKAPVVLTVYLTQ -NSKDASPRNETLAAATRAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTB8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BD799 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2BD30B ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115B6402 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I607_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase SHV-1 n=247 Tax=Bacteria TaxID=2 RepID=BLA1_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=14 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3Q8GRH3_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E029A93 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BD7F015 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q83YP9_ACIBA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLHKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011592A76 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001330315D ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A broad-spectrum beta-lactamase SHV-171 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000802882E ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2A5798 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A26B829 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUK9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADQRFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A9QW44_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSASSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A060KZ93_9BACT ---DVQQKLAELGRQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNLIAEKHVDGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNPTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A9ZTC6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0A1IR40_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P9EDA2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase protein n=1 Tax=Rhizobium etli CNPAF512 TaxID=993047 RepID=F2AJL3_RHIET ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCEAAVTLSDNTAGNLLLESFGGP -AGLNDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -KLIAWLVASTTGKERLRAGLPADWKIGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPMKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A2S8QYA3_PHOLU ---SLHKQLAELENSTKGRLGVMLINTANGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM -SQPELLAKHIHYRESDLLSYAPITHKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL -EAVNRFTQGIDDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVLGASQRE -QLIVWLKGNTTGDASIRAGAPAGWIVGDKTGAGDYGTTNDVAVLWPPKGAPVVLAVYFTH -PQQDAESRRDVLAAATRLVMAH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3G2M3D6_9BACT ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3G2M3L2_9BACT ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8RT90_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGADERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum humicireducens TaxID=1226968 RepID=A0A2R4VTL9_9PROT ----LAGRMAALEGRTGGRLGVAMLDTGTGRLQ-GWRVDERFPMCSTFKFLLAAAVLKAVD -QGRERLDRRIPVTSADLVPYAPFAETRLNGTPTVAELCEATMTLSDNVAANLLLPGVGNP -AGLTAFLRGIGDKTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMERLLVGDALRPDSSR -QLADWMIANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPENRPPLLVASYLTQ -TAKDFNQHDSIHAEVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C1KAC8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. T3 TaxID=638269 RepID=UPI000EAF694F ----FEQRLARIEADIGGRLGVAMLDTASGLQA-GRRQDERFPLCSTFKFLAAAALLARQD -RGEDHLSERVVFSAADLVEYSPVTEGRVGGTMTLADICEAAVTRSDNTAGNLMLARLGGP -AGLTAFVRSLGDRQTRLDRYETALNEARPGDPRDTTTPAAMLADMRELLLGTALSPASRE -QLTAWLVANETGDARLRAGLPTAWRIGDKTGSGERGTANDIAILWPTAREPVLVTVYLTG -SETDMNRRNAAVAEVGAALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. Tv2a-2 TaxID=113395 RepID=UPI0003F9193B ----LAEAFARVEADSGGRLGAGVLDTGTGATA-GHRQDELFPMCSTFKFLCVAAMLARVD -AGKEQLTRRIPVTSADLLDYAPVTKQHAGNDMTVAELCEAAVILSDNTAANLLLASMGGP -SAITQYARAIGDSVTRLDRTEPELNTAEAGDPRDTTTPAAMACNLQTLALGVALLPASRD -QLNKWLVGCKTGDARLRAGLPKDWRVGDKTGSGAHGTSNDIAVIWPAGRAPIMITAYLTQ -CPAGDDKRNAAIAAISKAVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter sp. LZ-6 TaxID=2570350 RepID=UPI001108151B -hnALIKTVEKVADDIEARVGFAAYDLESGQRW-EYRADQRFAMSSTFKTLACASLLHRVD -TGQANLGRKVHVSESDLVSYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EEVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEQSRE -QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ -TEASFEERNAAIAEIGEAIV--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9RMS3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella huaxiensis TaxID=2153354 RepID=A0A5P1KAU8_9ENTR ---AIQRKLTDLEKSSGGRLGVALINTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE -VDNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP -DKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA -QLVTWLKGNTTGGQSISAGLPAGWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE73_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQALRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6C7H2A2_ECOLX --------------GSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGIGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM40_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWLKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Alphaproteobacteria bacterium TaxID=91750 RepID=A0A212JU75_9PROT ---AAEDPFAAIEARIGGRLGVAILDTGSGASW-ARRDDERFPLCSTFKVLAVGAVLARVD -AGAEDLDEPVPIAAAEVVEYSPVTGRRAGGEMRLAEICEAALTRSDNTAGNLLLKRIGGP -AGLTAFARTLDDAVTRLDRWETDLNAAIPGDPRDTTTPEAMVDDLGALLLGDRLSPTSAE -RLIAWMRANATGDAKLRAGLPAGWQVADKTGGGDHGATADVAVIWPPTGDPLIVAVYIHE -SPASFDARNAAIAEVARR----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=R9UV61_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMXSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRXEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=2 Tax=Rhizobium meliloti TaxID=382 RepID=A0A3S2Q8E2_RHIML --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSEEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A516EKB2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella sp. Larv3_ips TaxID=1896943 RepID=UPI000EFB5767 --kAVQQKLAELEKSTGGRLGVAMIDTASNTQT-LYRADERFAMCSTSKVMAASGILKASE -TDKNLLNKHVDIKKSDLVNYNPITEKHLDSGMTLGELGAAAIQYSDNVAMNKLIAQLGGP -AKVTQFARSLGDETFRLDRTEPSLNTAIPGDNRDTTSPLAMAESLRKLTLGNALAEPQRA -QLVEWLKGNTTGAASIRAGLPATWQVGDKTGSGDYGTTNDIAVIWPDNHAPLILVTYFTQ -PQQDAKARKDVLAAAAKIVME-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTG5_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPAIMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B9512EA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSLRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter excellens TaxID=218670 RepID=UPI0007731AA7 -hnALIKTVEKVADDLEAHVGFAAYDVESGQRW-EYHADQRFAMSSTFKTLACAALLHQVD -RGQVNLGRKVHVSESDLVTYSPITEKHADGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE -QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPERQPIIVALYLTQ -TEASFEERNAAIAEIGEAIV--- ->[subseq from] Beta-lactamase n=1 Tax=Erwinia iniecta TaxID=1560201 RepID=A0A0L7T6H9_9GAMM ---TLAAQLSALEASANGRLGVALIDSGSSRQL-SYRGEERFAMASTFKALAAAAVLQRSV -EQPALLNKRIVYQQSELITYSPVTEKHLQQGMTVAELCAAAVELSDNTAGNILLREIGGP -QGITQLARRLGDNQTRLDRREPALNSAIPGDVRDTSTPLAMAGNLNQLALGKALPSAQQQ -LLIQWLKQSKTGAQSIRAGVPQGWQVGDKTGAGGYGTTNDLAILWPPQGKPLVLAVYFTQ -HNPQAEARRDVLASATRLVLAAw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii complex sp. CFNIH2 TaxID=2066049 RepID=A0A2K9P8P5_9ENTR ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKAMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT -RSVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000DABDFB ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVKYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. OV467 TaxID=2135592 RepID=A0A2V5B7I3_9PSED ----FHQRLEQLEATFAGRLGVVALNSNTGEVL-SYRGEERFPLCSTFKAMLAGAILQRST -LTPGLLGERIAYRKSDLVAYSPISEKHVQDGMTVAELCAATVQYSDNGAANLLMKLVDGP -EGVTTFARSIGDKHFRLERWETELNSAIPGDLRDTTTPLAMAHSLHRMVLGDALPAAQRQ -QLQEWLKGNTTGATRIRAGLPASWPVGDKTGTGDYGTTNDVAVIWPTAKAPLVLAIYLTQ -TRKDAAALNEPLAAATRIVLD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012328145 ------EQIKHSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Yersinia TaxID=2653513 RepID=UPI0011A5A6D1 ---TLDKQLAELERGANGRLGIAMINTANGTKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -SQPNLLDKHINYHESDLLSYAPITRKNLAHGMTVAQLCAATVQYSDNTAANLLIKELGGV -EAVNQFARSIGDQIFRLDRWEPDLNTAVPNDPRDTTTPAAMAMSMNKLVLGDALLPAQRN -QLAVWLKGNTTGDATIRAGAPKDWVVGDKTGSGDYGTTNDIAVLWPTQGAPVVLVVYFTQ -REKDAKPRHDVLASATKIML--- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=A0A2J9S9L3_YEREN ---SLDNQLAELEKSSNGRLGLALINTDKGTKV-HYRGGQRFPFCSTFKLMLAAAVLGHSQ -SQPNLLSKHIIYRESDLLDYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -EAVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LKKEAEPRRDVLAAATKIVLAH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0N9XKX3_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADELFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144121C7 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPLSEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATASAKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI0007859A79 ---DAETQLAELERACGGRLGVAGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSETVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKNRNDVVAEATRIAVR-- ->[subseq from] Beta-lactamase n=1 Tax=bacterium RRLBTPL III-2 TaxID=342580 RepID=Q3S2W9_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGLSLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0007CC169B ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGSRGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0012FB4DBD ---RLLEAIRQLESKSSGRLGVTVLDTQTGVSI-HHRGDERFPMCSTFKVLASAAILKRLG -DKLDGLDRRVRIEQSDIVENSQITREHVGPEMSLRELCEAAITRSDNTAGNLLLRNIGGT -AGLTAFARSLGDDVTRLDRVETELNEAAPGDVRDTTSPNAMAENYRRLVLGNALPPAARE -QLSKWMIANKTGDSRLRAGLPQGWRVGDKTGTGGHGTNNDVAIAWPPQRSALIVAVYLTG -ASVDFSGQNEVIASVGREVGKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rugamonas sp. FT82W TaxID=2692167 RepID=UPI00136D139E ------ALLAKLEVDSGGRLGVAAMNTADGRRL-LHRADERFPFCSTFKMMLSAAVLAK-- --GPALLKKRVRYSKADMVTYSPVTEDHIGRGMTVAALCEATIQTSDNTAANLLMKQIGGP -AAVTAFARSIGDMEFRLDRMETELNTALPGDPRDTTTPASMLESLHKLVLGDGLGAAQRK -QLKDWMLGTTTGDTRIRAGVPAGSQVADKTGTGSYGTTNDIGVIWQPGKAPVALVVYFTQ -PGKDDKARSEVIAEATRIVVE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8C4CA ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEYw ->[subseq from] class A beta-lactamase n=1 Tax=Curvibacter lanceolatus TaxID=86182 RepID=UPI0003A8CB0A ------GQWQALERESQGRLGVAVFDTQSGAWL-GHRLDERFAMCSTFKWLAAAQVLRRVD -QGLERLDRRIEFGREALLPWSPVTEKHAGGAMTVGELCHAAITVSDNAAANLLLRSFGGP -EGLTRFARQLGDPVTRLDRWEPELNEAIPGDPRDTSSPRAMVELLRQAVLGPALSVGSRQ -QLAQWLQATQTNVKRLAAGLPASWRVGSKTGTGAHGSTNDVGLYWPPDRGPIVVAVFLTE -SKASLEAREAVLAQVARRV---- ->[subseq from] Beta-lactamase SHV-8 n=1 Tax=Escherichia coli TaxID=562 RepID=BLA8_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARNTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella TaxID=160674 RepID=UPI000597F839 -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPLAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] Beta-lactamase n=9 Tax=Bacteria TaxID=2 RepID=A0A141RKP3_9BACT ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A5HJU3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DFFA30F ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSSFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Enterococcus faecalis TaxID=1351 RepID=A3FFR6_ENTFL ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -SPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=Q5DUJ2_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3KE69_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNNGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGA------ ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI00136BF30D ---AIQQKLADLEKRSGGRLGVALINTADNSHT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPIAEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI001389BD67 ---AIQQKLADLEKRSGGRLGVALINTADNSHT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPIAEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E3E2061 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYHQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL73_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLI--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6ALA0_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLI--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D70EB2 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQISDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPHNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus alvei TaxID=44250 RepID=A0A383RBG2_PAEAL --nQVHQQFVQLEKKYDARLGVYAIDTGTNQSI-TYRSNERFAYASTFKALAAGVLLQQNS ---IKQLDKVITYTKDDLVEYSPVTEKHVDTGMTLGELAEAAVRSSDNTAANLFLKELDGP -KGFEKALRQIGDQVTHADRFETELNEAAPGDIRDTSTPQALADDLKALTVGNALPPDKRK -LLTDWMRGNATGDKLIRAGVPKDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR -DKKDAAYQNELIAEAAKVTMK-- ->[subseq from] Beta-lactamase n=11 Tax=Enterobacteriaceae TaxID=543 RepID=A0A0B4U9F2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A extended-spectrum beta-lactamase TEM-8 n=1 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000016F834 ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD8401A --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000418F11C --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377TVL0_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPHNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=S6CQJ5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGEQGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7F06B --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGSMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005DD5755 ---SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLARGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALRPAQRS -QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATQIILS-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9AJR6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtARRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus heterorhabditis TaxID=880156 RepID=UPI0006C59345 ---SLHKQLAELENSAKGRLGVTLINTVNGQAI-QYRGDERFPFCSTFKLIVAAAVLHKSM -SQSDLLAKHINYSEVDLLSYAPIARKHLDQGMSITQLCAATLQYSDNTAANLLIKELGGV -AAINHFTQSLGDHTFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVNKIAFGAVLAASQRD -QLIDWLKGNTTGDASIRAGAPAGWVVGDKTGGGDYGTTNDVAILWPPKGAPVILAVYFTQ -FQQDAESRRDVLASATRLVMEH- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=F6MFV3_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium sp. CL33Tsu TaxID=1798191 RepID=UPI000B81EF52 ---DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD -RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP -KGLTQYARSLGDATFRLDRRETELNEAAPGDPRDTITPAHILKDLQKTVLGNALAKSSRD -QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD -PKGTADSRNEIHRKVASLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Jiella sp. 40Bstr34 TaxID=2696469 RepID=UPI0013BC71B9 ----VTTAIAKAESELGARVGAMIVDTRSGKTW-SVRAQERFPLNSTFKAFACAAVLGGVD -AGEAALDQQITFTADDLVTYSPVTETRIETGMTLGEVCDAAMTMSDNTAGNLVIESLGGP -DGVTRFMRQIGDAETRLDRTEPTLNEATPGDPRDTTTPEAAARSLEKLVLGDALSPKSRR -QLERWLVGNKVGDPLLRAGFPKSWKVADRTGAGGHGSRSIVAVAWPPERRPIVAAIYLTG -TEASMEARSAAIADIGKAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=A0A127QL76_9BURK ----FVKKMRQIEAQSGGRLGVAILDTQTGLAH-SYRGDERFPMCSTFKLLAAGFTLKRVD -LGQEQLTRRIRFNAADLMSYSPVTEKHVGGDMSVAELCEAAITLSDNTAANLLLHSFGGP -SLLTAYLRSLDDKVTRLDRIEPDLNESTPGDPRDTTSPKAMLSTMRQLVLGTALAPGSRE -QLTNWLLANKTGDKRLRALLPSGWRVADKTGSGSHGSTNDIGVLFPPNRAPVLVASYLTG -TKANAATREVALAEVGHLT---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. M1 TaxID=2035453 RepID=UPI000BE7DE50 ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEASCN -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9I3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVAAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAACIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000659D03E ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAGLIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G1EC65_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYSQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Reyranella sp. TaxID=1929291 RepID=A0A521QLV9_9PROT ---DATVKFAELERRNGGRLGVAAFDSASGRRI-GYRGEERFPMCSTFKFLASAFALARVD -RGEERLDRRIVYSAQDLVTYSPITKDHVGPALSVAELCDATMTLSDNTAGNLLLASFGGP -AGLTAYARSLGDQTTRLDRIETALNEGLPGDPRDTTSPVAMLGTMQRLLLGDALSAASRE -RLTGWLLANKTGDKRLRAGMP-GWKVGDKTGTGGNGSANDIAIVWPTGRAPLLVTVYYTG -STISDEARNDVIAEAGRIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A0M4G455_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium valentinum TaxID=1518501 RepID=UPI0009E77C19 ---RLIGEIKRLESESGGRLGVCVLETATGTRH-VHRGDERFPMCSTFKALAAAAILARVD -AGNEQLTRRITFDASALVVNSPVTEKRVGGDMTVAEICDAAVTRSDNTAGNLLLAGIGGP -SGLTAFARSLGDEVTRLDRDEPSLNEALPGDPRDTTTPNAMASNLQALILGKALSAASRE -QLTAWLIANKTGDTRLRAGFAKGWRVGDKTGTGGRGTNNHVAVVWPPSAAPMVIAVYLTG -ATVSFEQQNAIVASVARAVS--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A6B3K0A9_RHILE ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKVLAAAFVLARAD -KGEESFDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter amalonaticus TaxID=35703 RepID=A0A2U4DMF8_CITAM ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT -RSVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZS0_KLEPN ------EQIKQSEGQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B6975F ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVXRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000447071A ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKQLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C1F7365 ---ETLVKVKDAEDQLGARVGYIEMDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013B70E9D ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=A4LAC3_ACIHA ---KTLVKVKDAENQLGARVGYIELDLNSGKILeSFRPEKRFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQSDVVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Cereibacter changlensis TaxID=402884 RepID=A0A4U0Z3Q0_9RHOB ------SAFKALEEQGGGRLGVAVLDTETGDTS-FWRGDERFAMASSFKAPLCGAVLARVD -AGDEQLDRPIPISADDLIPYAPTVEKHIGGSLTVAQLCEATITLSDNVAANLLLDTLGGP -SGLTAFLRSIGDDVTRLDRFEPELNEATLGDPRDTTTPRAMADTLNSLLLGGVLSVESRT -QLADWLKANQTGDDRIRAGLPEGWQIGDKTGTSGTGTFADIAILYPPQGKPILMAVYLAE -TDVSTKEANGVHAGVAQLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE36E2D ---DLAAAFKTLEERTGARLGVAAHDTGSDNRI-GYREDERFAMCSTFKFLAAAAVLARVD -REEEELNRIVKFKKSDLVDYSPVTEKHLDSGMSLAAICEAAVTMSDNTAGNLMLDNIGGP -KGLTEYARRLGDATFRLDRRETDLNEAKPGDPRDTITPIAILKDLQKTAIGDALGKSSRD -QLIEWLLGSKTGDKRLRAGLPKDWSVGDKTGTSDSGMANDIAVIWPPERKPILLAVYLYD -PKGTPDSRNEIHQKVAKLVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=UPI000CF40EB1 ----AAPALARVEAQLGGRLGVAALDTATGARV-GHRAAERFAMCSTFKALLAASLLARVD -QGKLTLDRRVTYRASDLLEHAPVTRAHLAEGLTVEELCAAAVEISDNTAANLLLAQIGGP -AGLTAYIRSLGDQVTRFDRNEPTLNTNVPGDPRDTTSPDAMTDTIRVLLVGDALSEASRA -RLKSWMVRSTTGLARLRAGLPKDWVVGDKTGTGENGAANDVAVAWPPSRAPIVIACFVDA -PSASVDARNAAHAEAARIVAEVf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Mycoplasma mycoides TaxID=2102 RepID=UPI001019DE04 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGXVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Rahnella inusitata TaxID=58169 RepID=A0A419M6P6_9GAMM --kAVQQKLADLEKSTGGRLGVAMINTADNSQT-VYRGEERFAMCSTSKVMAASGVLKASE -QDKNLLNKHVDIKKSDLVNYNPITEKHLDTGMTLGELGAAAIEYSDNVAMNKLIAQLGGP -AKVTQFARSIGDETFRLDRTEPTLNTAIPGDKRDTTSPLAMAQSLRKLALGDALAEPQRA -QLVAWLKGNTTGAASIRAGLPASWTVGDKTGSGDYGTTNDIAVVWPDNHAPLILVTYFTQ -PQQDAKARKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=G1JY45_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2R8G1S5_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEESFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6AL88_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Uncharacterized protein (Fragment) n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1IDJ4_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00129DA628 ------EQIKLSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q5DUI8_KLEOX ---AIQQKLANLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium tarhaniae TaxID=1187852 RepID=A0A0J6T156_9RHIZ ---DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKALAAAAVLARAD -TGKDDLNRRITYGRDAVLSYAPVTAKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP -GGITAFAHAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGQALTDKSRA -RLAGWMNESPTGLKRVRAGLPEGWRVADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIARSf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2D95B9 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWEKELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium yanglingense TaxID=61013 RepID=A0A245Z7K2_9RHIZ --dDIERRLAELENRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP -KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE -KLIEWMLANTTGDARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE -ATAPVKELNLVFAEVAKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTA8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPADWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] BETA-LACTAMASE TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000011206D ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDATAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0013EF5EFB ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000D579BD ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVYNSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q840S0_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTIGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Terriglobus albidus TaxID=1592106 RepID=A0A5B9EF56_9BACT -------FLAQLEKEKGGRLGVSVLDTQTGAHA-GHRAGEAFPMCSTFKLSLAAQVLARVD -HGEEKLDRLVTYTQADLLSYAPVTKEHVATGMTVGALCEAAITLSDNTAANLLLVTVGGP -AGFTRWLRSLGDTATRLDRNEPTLNSAEPGDQRDTTTPSAMLATLQKLTLGNVLSPASRK -QLNDWMLATQTGLKKIKAGLPADWKEGDKTGSGDNSTTNDIAVLYPPDRKPVLITVYYTG -SKLETDQSNLVFQEIGRK----- ->[subseq from] Beta-lactamase n=2 Tax=Variovorax sp. OV700 TaxID=1882826 RepID=A0A1G8KY70_9BURK ---SAEAQLAALESSVGGRLGVAAFDTATGARV-QHRATERFPLCSTFKTMLAAAILERSA -RDSALLERRVSYGKSDILPHSPITEKYLEQGMAVSAMCAATIQYSDNAAANLLMKILGGP -SAVTAFARSIGDQAFRLDRWETELNSAIPGDPRDTTTPEAMAASLQRLVLGDGLGATQRG -QLQNWLLGNTTGATRIRAGVPADWKVGDKTGAGSYGTVNDTGVLWPPVGAPLVLAVYLTF -PTKDAEGRNDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A485UQB8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3S4T2_KLEPN ------EQIKLSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rubeoparvulum massiliense TaxID=1631346 RepID=UPI0009757614 ---ETSRKFMQLEKEFDVRLGVYAIDTSTNRTV-AYRPDERFAYTSTFKVLAAGAVLQQNS ---IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLQKLGGP -NGFEKALRQIDDNVTEADRFEIDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNDKRT -ILTDWMRENTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTR -DTKNATYNNELIAKAAKVALNAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE6D769 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRFAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDD8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVGYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D3AD2AA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERLPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0006459C33 ------EQIKLSESQLSGRVGMIEMDLTSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010327675 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q8RMG3_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIVEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A089MWI9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALID-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A292CDR2_PROVU --nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIAKAAEIVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus glycinifermentans TaxID=1664069 RepID=A0A1C3SFF6_9BACI ------NQFSRLEDQYDARLGVFALDTGTNKTV-AYRADERFAYASTHKALAVGALLQQKS ---IADLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP -SGFKQSLREIGDNVTNPERIEPDLNEVKPGETHDTSTPKALAKSLQAFTIGDALPKEKRE -MLVDWLKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEVAKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003FC61A4 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTLPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=UPI00048EDF1A -hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAAAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -TKQDAPWNSETIAAATRVVVEAw ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=UPI00083DE284 -hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAAAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -TKQDAPWNSETIAAATRVVVEAw ->[subseq from] Beta-lactamase n=6 Tax=Gammaproteobacteria TaxID=1236 RepID=Q8KRG7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009C44BE8 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Collimonas arenae TaxID=279058 RepID=UPI0007782166 ----FVKKMRQIEAQSGGRLGVAILDTQTGLAH-SYRGDERFPMCSTFKLLAAGFTLKRVD -LGQEQLTRRIRFNAADLMSYSPVTEKHVGGDMSVAELCEAAITLSDNTAANLLLHSFGGP -SLLTAYLRSLDDKVTRLDRIEPDLNESTPGDPRDTTSPKAMLSTMRQLVLGTALAPGSRE -QLTNWLLANKTGDKRLRALLPSGWRVADKTGSGSHGSTNDIGVLFPPNRAPVLVASYLTG -TKANAATREVALAEVGHLT---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE79_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEMHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ESJ9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIE-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus delbrueckii subsp. bulgaricus TaxID=1585 RepID=A0A5C7G8U0_LACDE ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGECGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A5N8G2N8_9ENTR ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A6B8MHP4_KLEOX ---TIQQKLAELEKSSGGRLGVALINTADNSQT-LYRGNERFAMCSTGKVMAAAAVLKESE -NNKDVVNKRLEIKESDLVVWSPISEKHLKNGMTLAELSAATLQYSDNTAMNKIIGYLGGP -DNVTAFARSIGDTTFRLDRTEPTLNTAIPGDERDTTTPQAMAESLQKLTLGNALGEQQRA -RLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENQAPLVLVTYFTQ -PQQDAKNRKDVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A2Z3EW51_9ENTR ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Enterobacteriaceae bacterium ML5 TaxID=2507584 RepID=A0A4S3LL16_9ENTR --kAVQQKLAELEKSTGGRLGVAMIDTASNTQT-LYRADERFAMCSTSKVMAASGILKASE -TDKNLLNKHVDIKKADLVNYNPITEKHLDSGMTLGELGAAAIQYSDNVAMNKLIAQLGGP -AKVTQFARSLGDETFRLDRTEPSLNTAIPGDKRDTTSPLAMAESLRKLTLGNALAEPQRA -QLVEWLKGNTTGAASIRAGLPATWQVGDKTGSGDYGTTNDIAVIWPDNHAPLILVTYFTQ -PQQDAKARKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI00005F9E03 ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LKKEAEPRRDVLAAATKIVLAH- ->[subseq from] Beta-lactamase n=1 Tax=Solimonas aquatica TaxID=489703 RepID=A0A1H9I0M1_9GAMM ---ALLTQLGQIEQSVNGRLGVAIEDSHSGRRW-QYRGDERFPMCSTFKLLACAALLARVD -AGLAQLQQLQAYGEDELVRYSPVTQDYAGKGLSWAQLCEAALTRSDNTAGNLILRAIGGP -AGLTAFARSLGDALTRLDRWETELNEARPGDPRDSTTPLAMNANLRTLLLGERLKPASRE -QLIAWLLANQTGDARLRAGLPRDWRVGDKTGAGEQGTNNDIAIAWPPQRAPLLISVYLTQ -SPASFEARNQALAAVAQALVRH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0007EB8FCB ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAASFALARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPMKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) TaxID=393305 RepID=UPI0006DBD7C2 ---SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLACGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATQIILS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDA824A --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia aspalathi TaxID=1324617 RepID=A0A1I7E7D4_9BURK ---AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD -RGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSPSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARSNAAIANVGALIV--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RHY2_9BACT ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPPSWGVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B6427 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIHLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPN9_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKCE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRVPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E0962C4 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKLVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A125R6L3_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMTDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B2EE39 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEAAYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus heterorhabditis TaxID=880156 RepID=A0A5B0VHH5_9GAMM ---SLHKQLAELESSAKGRLGVTLINTVNGQAI-QYRGDERFPFCSTFKLIVAAAVLHKSM -SQSDLLAKHINYSEVDLLSYAPIARKHLDQGMSITQLCAATLQYSDNTAANLLIKELGGV -AAINHFTQSLGDHTFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVNKIAFGAVLAASQRD -QLIDWLKGNTTGDASIRAGAPAGWVVGDKTGGGDYGTTNDVAILWPPKGAPVILVVYFTQ -FQQDAESRRDVLASATRLVMEH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ2_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKRVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia plantarii TaxID=41899 RepID=UPI0008707720 ------RQLAALDGSFDGRIGVAALDTGSGARL-LHRADERFAFCSTFKTILVSALLTRAA -GDPRLLSSVIRYRAQDLVRYSPVSEKHVDTGMSVAGLCAAALQYSDNSAANLLIRMVGGP -AAVTAYARSIGDRRFRLDRIETELNDAVPGDERDTTTPAAMLDTLRRVTLGDALDASGRA -RLISWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLVVYTTR -DRKDAEYDNAAIASAARIVTAAf ->[subseq from] Beta-lactamase n=1 Tax=Jiella endophytica TaxID=2558362 RepID=A0A4Y8RIS9_9RHIZ ------RAVEKAGSDLGARVGVMIVDTQSGKVW-SARADERFPLNSTFKAFGCAAVLGQVD -AGEASLNETITYSADDLVTYSPVTEKHVDTGMTLGEICDAAMSMSDNTAGNLVIESLGGP -DGVTQFMRAIGDGETRLDRTEPTLNEAAPGDPRDTTTPKAAAASLQTLVLGDALSETSRQ -QLKSWLIGNKVGDPLLRAGFPKDWAVADRTGAGGHGSRSVIAVAWPPERKPIVAAIYLTG -TEASMEARSAAIAEIGKAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum hiltneri TaxID=341045 RepID=UPI00069E976B ----VVSRLAKLEASVAGRLGVEILDSGTGRRW-GYRADERFPMCSTFKFLAASAVLRRVD -TGAEQLDRRIVYGEDVLVNYSPTTSKHVGGDLSLAQLCEAAITLSDNTAANLILHSLGGL -GPFNKFVRSLGDDTTRLDRFETELNTSIPGDPRDTTTPTAMTGNLQKVLLGDALSAASRR -QITAWMLANKTGDRRVRAGMQPGWKVGDKTGSGDYGTTNTVAIIWPPQGAPLLASIYLTE -TRAPEEQRNAVLAEVGKLIV--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A385FUJ6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDARVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium azibense TaxID=1136135 RepID=A0A4R8A9G7_9RHIZ --dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGELCKAAITLSDNTAGNLLLESVGGP -KALTKWLRSIGDRASRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE -KLIEWMLANTTGNARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE -ATAPVKELNPVFAEVAKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4S350_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVDGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium gallicum bv. gallicum R602 TaxID=1418105 RepID=A0A0B4X006_9RHIZ --dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYDQDKLVSYSPETEKHVGGEMSVGELCKAAITLSDNTAGNLLLESVGGP -KALTKWLRSIGDRASRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE -KLIEWMLANTTGNARLRAGLPGAWKVGDKTGTGDNGTAADIAIIWPKGRGPILVTAYIAE -ATAPVKELNPVFAEVAKIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=UPI000648C5F0 --dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -AAAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005CDCEBC ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6AL65_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLIKH- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCBF5F2 ---TLDQQFKQLENDFGARLGVYALDTATGLTI-RYREDERFAYASTSKALAVGAVLAQSP ---VEELDKRITYTSDDLVSYSPITKDHVGKGMTIRELCDAAVRYSDNTAANLLFKELGGP -EGFAKVLKEIGDDVTNPVRIEPDLNEATPGDLRDTSTPKALATSLQAFTLGEVLSADKRS -ILINWMKENTTGDELIRAGAPTGWVVGDKSGAGSFGTRNDIAVVWPPDRAPVVISILSSR -DTKDAKYDNALIAQAAKIALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0E3GM50_PSEAI ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMVATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2B5688 ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRANERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A209APQ5_YERFR --eSLDKQLAELERKSNGLLGIAMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHIKYHESDLLSYAPITRKNLAQGMSVSELCAATIQYSDNTAANLLIKELGGI -AAVNEFARSIGDHTFRLDRLEPDLNTALPNDPRDTTTPAAMAASLNKLVLGDALPAAQRE -QLAIWLKGNTTGGETICAGAPADWIVGDKTGGGDYGTTNDIAVLWPPTGAPIILVIYFTQ -REKDAKPRRDVLAEATKMVLSH- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010344399 ------EQIKLSESQLSGRVGMIEMDLSSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGEQGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q5DUJ0_KLEOX ---AIQQKLADLEKRSGGRLGVALINTTDDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTD5_KLEPN ------EQIKLSESQLSGRVGMIGMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Superficieibacter electus TaxID=2022662 RepID=A0A2P5GGS6_9ENTR ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQLAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FDC25 ------EAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG -SKLEALERRVRIEQADLVEYSPVTREHIGGKMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTSFARSIGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD -QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. KO164 TaxID=1798192 RepID=A0A1B9VH43_9PROT ---RLLDAVQTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD -RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP -DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLLGDALSLESRQ -ILEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIVAIYITQ -TSASMEERNAAIADLGQEIA--- ->[subseq from] Beta-lactamase n=1 Tax=Cobetia crustatorum TaxID=553385 RepID=A0A558HM76_9GAMM -----QEALRAIEKKVDARIGVTVLDTADGSRF-SYRGDERFPMSSTFKALACGSLLALVD -DKQESLQRKVKIMPDDVVTYSPVTETQTEGDMTLSELCSATITTSDNTAGNLILAALGGP -QGLTGYLRSLGDEKTRLDRTETALNEATPGDVRDTTTPTAMVMTLEKLLLGDALSETSRL -KLQGWLLANTTGDDKLRAALPADWQIGDKTGGGGYGTNNDIAIIWPPGNAPLIVAVYLTK -STASIAERNAAIADIGRLLVS-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Campylobacter hepaticus TaxID=1813019 RepID=UPI00104EC8C8 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNXERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ5_KLEPN ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase protein n=2 Tax=Rhizobium TaxID=379 RepID=B3PTM9_RHIE6 ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATTPAKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Leptolyngbya sp. NIES-2104 TaxID=1552121 RepID=A0A0N7Z4R7_9CYAN ---SAQTQFAKLERTLAGRLGVFALNTANRAQL-SYRANEPFPLCSTFKILLTSAILKRST -QVEGLMQQRIRYQQRDLVTYSPITEQHVKEGMTVAALCAAAMQYSDNTASNLLMKILGGP -GSVTAFARSIGDRQFRLDRWETALNSSIPGDRRDTSTPAAMGLSLQQLALGNALEPHLQA -QLQAWLRGNTTGAARIRAGVPANWQVGDKTGTGDYGTANDVAVLWSPQRSPVVVAIYTTQ -GEKDAKARNDIIASAARIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0M4FM41_KLEOX ---TIQQKLADLEKSSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI000BE8A457 --dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVTELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDE1_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKAGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas graminis TaxID=158627 RepID=A0A4R7W6G9_9PSED ----IQQQLADLERRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAAHVLARVD -QKQEDLSRRIVYSAEQLVAYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANLLLDSMGGP -DGLTAWLRSIGDTQTRLDRREPDLNENRPGDLRDTTTPVAMLQTLNTLVLGDELRLASRD -QLTAWLVNNQTGDKKLRAGIPGGWRVGDKTGSGANNASNDVAVIWPGDRPPILVTVYYTG -SKASGDQSNALMADIGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia kristensenii TaxID=28152 RepID=A0A0T9T9C2_YERKR ---SLDNQLAELERTANGRLGVALINTANGSKV-QYRGGQRFPFCSTFKLMLTAAVLGQSQ -SLLGLLDKHIRYHESDLLSYAPITRKNLAQGMTVSQLCAATIQYSDNTAANLLIKELGGL -EAINQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASIHKLVLGEALKTPQRE -QLVVWLKGNTTGDATIRAGVPTDWIVGDKTGSGDYGTTNDVAVIWPSQGAPLVLVLYFTQ -RQKDAESRRDVLASATKIVLSH- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A6A7ZWF0_RHIML --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005CDCEC6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRYYGELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia azotifigens TaxID=2057004 RepID=A0A5C6VQB2_9BURK ---AFKKQLAQIEAQVGGRLGVAILDTASGKQH-GWRMNERFPMCSTFKVLLASAVLTRKD -QGKEELGRKVVYAKDVVVANSPVSGPRAGGDMTVSELCEAAITRSDNTAANLLLESIGGP -AALTAFVRGMGDKVTRLDRNEPTLNEALDGDPRDTTTPAAMLADLRALLLGEHLSAASRE -QLTAWLVANKTGDARLRAGLPKDARVGDKTGTGERGTSNDIAIVWPAGRPPILVTVYLTG -ATASAAQRDAAIAKVGALAAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A3S0QDQ6_9RHIZ --dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGATRLDRTEPTLNEGKKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGTLGDIAVIWPPDRGPIVAAVYIAE -ATAPVTELNPVFAEVGRMIVE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2A5B02 ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRN -TPATMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=B8R7R2_9BACT ---TLAAQLSALEASANGRLGVALIDSGSSRQL-SYRGEERFAMASTFKALAAAAVLQRSV -EQPALLNKRIIYQQSELITYSPVTEKHLQQGMTVAELCAAAVELSDNTAGNILLREIGGP -QGITQLARRLGDNQTRLDRREPALNSAIPGDVRDTSTPLAMAGNLNQLALGKALPSAQQQ -LLIQWLKQSKTGAQSIRAGVPQGWQVGDKTGAGGYGTTNDLAILWPPQGKPLVLAVYFTQ -HNPQAEARRDVLASATRLVLAAw ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000D654FC1 ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella huaxiensis TaxID=2153354 RepID=A0A564GUD4_9ENTR ---AIQRKLTDLEKSSGGRLGVALINTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE -ADNQVLNKRLEIKKSDLVVWSPVTEKHLQSGMTLAELSAATLQYSDNTAMNKMIGYLGGP -DKVTAFARSIDDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA -QLVTWLKGNTTGGQSISAGLPAGWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Caballeronia sordidicola TaxID=196367 RepID=A0A242N2B9_9BURK ---KISKRLARIEASTSGRLGVSVLDTGSGAHA-GLRADEAFPMCSTFKFLAAGFVLARVD -KGEEDLKRKIVYSKSDLVDYSPVTQHHADSALSVAALCDAAITLSDNTAANLLLASFGGP -AALTAFVRTLGDTQTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA -QLRDWLIANKTGAKRIREKLPKDWRVGDKTGTGSHGSTNDIAIIWPPKRAPLLVTAYLTL -TSAQTARREAAIADIGGLVVSSf ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=F8TCS6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q0PGR7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3LUK8_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWCADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005DC22EA ---SLDKQLAALEHSANGRLGIAMINTANGTKI-LYRGAQRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLVKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDASIRTGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q6R7N4_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIAEKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A120HUS1_ACIBA ---ETLVKVKDAEDXLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAS----- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDBBC84 --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESLGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK -RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DHOC27 TaxID=2303330 RepID=A0A372K7X0_9BURK ------ARFAQLEGTFGGRLGVYALDTGNGARI-MYRESERFPFCSTFKVILAGAILTMSE -RNEGLLKRRIKYSQKEVVHYSPISEKHVADGMTIEELCRAALQYSDNTAANMLIAQAGGP -SGVTSFAHSIGVDEFRLDRWETALNDAIPGDPRDTATPAAMAHALQVLTLGDALPAALRE -TLQTWLRGNTTGTKRIAAGVPAGWQVGDKTGTGDYGTGNDLAILWPPGRKPVILAVYHTN -SDANAQPNDQVIAEAAKIVAA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sp. BL10I2N1 TaxID=1938796 RepID=A0A4R6ERV6_9BURK ---SAQDRLTVLETSSGGRLGVAALSTAGSTQL-DYRANERFAVCSTSKVLIASAILKRSE -KEAGLLEQRIHYTKSDLVAYSPVSERHMDSGMTVAELCAAALDYSDNTSANLLMKLLGGP -SAVTAFARSIGDETFRLDRWETELNSAIPGDLRDTSTPAAMAQSLQRVALGDALAAPQRN -QLQAWLRANTTGSMRIRAGAPADWIVGDKTGTGDFGTTNDIAVLWPPAKPPVIVALYFTQ -REKDAKPRNDVLASAARIVVESf ->[subseq from] class A beta-lactamase n=1 Tax=Proteus cibarius TaxID=626774 RepID=UPI000D68BA63 --nTIEEQLNTLEKYSQGRLGVALIDTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIVKATEILTKEf ->[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000950CE19 --nTIEEQLNTLEKYSQGRLGVALIDTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIVKATEILTKEf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A347VB55_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEAAYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YPM8_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKSDTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase n=2 Tax=Yersinia enterocolitica TaxID=630 RepID=A0A485DJC8_YEREN ---SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITCKNLARGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATQIILS-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. PDO1-076 TaxID=1125979 RepID=H4EZM6_9RHIZ ---QFAQALEAIEARIQARLGAFVLDTETGTTL-GYRADERFPMCSTFKAIAAAAVLSRVD -AGKEDLSRRLHWKKADLIAHSPVTEKHVKDGLTLTELCHAATTVSDNTAANLMLEAIGGP -SGFTAFVRSVGDPVTRIDRMEPALNSAKPGDKRDTTSPAAMAALLKTLVLDDALSPASRD -QLGQWMVANTTGGTKLRAGLPRGFTVGDRTGAGANGTNNVVAVIWPPQRKPLVATVFITE -TQTPRPETDPAMAEIGRLLT--- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus cibarius TaxID=626774 RepID=UPI00131FB24E --nTIEEQLNTLEKYSQGRLGVALIDTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIVKATEILTKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001441C409 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q09Q12_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGGSLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter superfactus TaxID=1774969 RepID=A0A1E3VVX1_9RHIZ --eALARAFAEIEGHVGGRLGVAVLDTGSGLSA-DLRGDERFPLCSTFKWLAAAALLSRVD -AGTESLGRPIGIRAQDIVTYSPATEKHVGGTMTLGEICAAAITLSDNTAGNLMLGALGGP -EAVTAYARSLGDQTTRLDRTEPTLNDVPPGDPRDTTTPLCMLGDLQAVLVGEALSEASRA -QLIAWLLANTTGETRLRAGLPSTWRVGDKTGTCNANTANDVGIVWPPDRAPILIAAYLAE -TTASREAQNAALADVGRAVAT-- ->[subseq from] Beta-lactamase n=6 Tax=Proteobacteria TaxID=1224 RepID=R4RPE6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAKRNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4B TaxID=2714925 RepID=UPI001408335B ---SVSEPWSRIEKQSTGRMGVAVLDTAHGGWD-GQRLDERFPMCSTFKWLAAAHVLQRVD -QGREQLDRRIRFERKALIDYSPVTEPQAGKNMTLAELCHAAITVSDNTAANLLLETLGGP -QGMTAFARSLGDDVTRLDRWEPDLNESKPGDPRDTTSPRAMATLLQQLVLGDVLSPRSRE -QLVQWMRATSTNRNRLAAGLPQGWKIGSKTGSSGTGSVNDVGVFWPPNRPPIIAAVYVTQ -GTGSTKSIEPAIAAVAQHIT--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI000C1CA0B1 ------DEFIQLENKFGARLGVYAIDTGTSRTI-AYRPEERFAFASTYKALAAGAVLQQSS ---IANLDKVITYTKEDLVTYSPITEKHVETGMTLRDICDAAIRYSDNTAGNLLLKELGGP -KGFETVLKKIGDNVTTSARFETDLNQAIPGDTRDTSTPKALATTLQAFTVGDVLPTDKRK -LLTDWLRGNTTGAKLIRAGVPEGWQVGDKTGAGSYGTRNDIAIVWPPNRDPIIIAILSSR -DKQDSAYNDDLIAQAAKITMD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A4U9LAJ1_ECOLX ---------KDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A654NBN4_9RHIZ ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=A0A0T9M378_YERIN ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVIYFTQ -LKKEAEPRRDVLAAATKIVLAH- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) TaxID=393305 RepID=A1JML9_YERE8 ---SLDKQLAALEHSANGRLGIAMINSGAGTKI-LYRGAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLACGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALRPAQRS -QLAAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATQIILS-- ->[subseq from] class A beta-lactamase SHV-116 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00042D6680 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWHADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000671E4AF ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERQIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDARVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RE33_9BACT ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIPDKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000EF28063 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTSASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3YA66_KLEPN ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMLDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A291NXZ6_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMVSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLVDGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D620_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C0LSK2_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A220NZ16_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI001399448B ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus pacificus TaxID=2026187 RepID=A0A5C4ZJQ8_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI86_ECOLX ---DVQQKLAELEWQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000DC7E176 ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPASMAERNQQIARIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A25DB63 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEPw ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. YMA4 TaxID=1593482 RepID=UPI000DD1355C ------SAFAALERKFKGRVGVAAIDTASGKVI-GNRQDERFPFCSTFKTIVAAAVLARSA -TEPGFLGKRLRYTQADIKPHSPVSEKHVEAGMTAAELCAATIQYSDNAAANILMRELGGP -AAITAYARTLGDTTFRLDRWETELNSAIPGDERDTTTPLAMARTLQKLLVGDGLPPAQRQ -QLKDWMVGNTTGDTRIRAGVPKGAVVADKTGTSGYGVANDMGVIYLPQRAPIVLVVFTHG -ATEQAEARSESVAEATSVALR-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI000FF8CB60 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Herminiimonas sp. KBW02 TaxID=2153363 RepID=A0A3N7A510_9BURK --qTAQEELKKIEVRSGGRLGVSAINMASDQRV-EYRAEERFPFCSTFKVMVAAAVLQRST -SDTSLLQKRIRYKKEDTEKYAPITQKYLADGMTVSELCAATLQYSDNAAANFLMKELGGP -AAVTAYMRSIGDNVFRLDRWEPELNSALPGDERDTSTPAAMENSLEKLALGRALPQPQRE -QLMNWLKGNTTGGKRMLAGVPGGWQVADKTGTGSYGTTNDIGILLPPGGSALVTAIYFTQ -NGKDAAPREDVIASATRIVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8KRG8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATFGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7AD308 ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00044E93B6 ------EQIKQSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0R7FDJ3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE0_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARMD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RTG7_9BACT ---DAANQIAAIEARLGSRIGVAALDTGSGKRL-DYRAEERFPMCSTFKFLAATAVLKRVD -KKQDRLDRFISYDAKDILEYAPITKAHLKEGMTLGALCEAAIEQSDNTAGNLLLDAIGGP -AGVTNFARSLVDQVTRLDRKEPDLNSAIPGDERDTTTPGSMLADMTRILTGDVLSRSSRR -QLKDWLQRNKTGETMIRAGVPTDWIIGDKTGRGANGATNDIAIMRPPDRAPMLLAIYSLG -STATANDRAAAIAEVAKIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia aleksiciae TaxID=263819 RepID=UPI001427B427 ---SLDNQLAELERTANGRLGVALINTANGSKV-QYRGGQRFPFCSTFKLMLTAAVLGQSQ -SLLGLLDKHIRYHESDLLSYAPITRKNLAQGMTVSQLCAATIQYSDNTAANLLIKELGGL -EAINQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASIHKLVLGEALKTPQRE -QLVVWLKGNTTGDATIRAGVPTDWIVGDKTGSGDYGTTNDVAVIWPSQGAPLVLVLYFTQ -RQNDAESRRDVLASATKIVLSH- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. M10 TaxID=1324586 RepID=A0A2A6L7R8_9RHIZ ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPNAMLDTLGNLTLGSVLTEASCN -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9K582_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDELNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A3FFR2_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGTVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B529681 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q9L760_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. FW305-17 TaxID=2070681 RepID=A0A2N8FF90_9PSED ----LRKPLQQLEATTGSTIGLWALDTGSGQQL-AWRAEERFAFCSTFKAVLAGAILHRSQ -AEPGLLERRIAYGAEQLVVYSPVTEKHVGAGMTVAGLCAAAVQYSDNTAGNLLLELVGGP -PGLTAFARSLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLGDGLAAAERQ -QLQAWLKGNTTGDARIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -AKADAPWNSETIAAATRVVVDAw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI00077C9547 -----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVLQQNS ---LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP -DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT -ILTDWMRGNTTGDELIRAAVPMGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR -DTEDATYDNDLIAKAAKVVLKEf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQZ8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVMIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. SDF0028 TaxID=2133754 RepID=A0A544VGT8_9BACL --nQVHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYASTFKALAAGVLLQKNS ---IEQLDKVITYTKDDLVEYSPITEKHVDTGMTLEELAEAAIRFSDNTAVNLFLKELDGP -KGFEKALRQIGDQVTHADRYETELNEAVPGDIRDTSTPQALADDLKAFTLGNALPLDKRK -LLTDWMRGNATGDKLIRAGVPKDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR -DKKDAAYHNELIAEAAKVTMN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI000554E4F0 -----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALATGLVLQQNS ---LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP -DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT -ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR -DTEDATYDNDLIAKAAKVVLKEf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A2K9YZQ7_RHILE ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L3IN55_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNGAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A444HVY2_RHILE ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A0A564NJ72_9ENTR --nAIQQKLADLEKSTGGRLGVALIDTTDNSQI-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNKDVVNKMLEIKASDLVVWSPVTEKHLQSGMTLAELSAAALQYSDNTAMNKMIGYLGGP -EKVTAFARSIGDVTFRLDRTEPALNTAIPGDERDTTTPLAMAESLHKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PLQDAKSRKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 88A TaxID=1131813 RepID=UPI000362BD2E --rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAVLARVD -RGEDGLDRRLRYEPREIVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP -AGLTGHIRGFGDATTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPQDWRIGDKTGSGENDTANDVAVIWPPRRAPLVLTVYLTG -ARTSPEARSATIASVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiaceae bacterium CPCC 101076 TaxID=2172049 RepID=UPI000E0DBE1A -----EAELADLERRSGGRLGVSVLDLGSIRRF-GYRPDERFAMCSTFKLLAAGYVLARVD -RGEERLDRRIVVRESDLVPYAPAVEKRLGGDMTMSELCDAAITLSDNAAANLILASYGGP -AGLTAYLRSIGDDVTRLDRNEPTLNEATPGDPRDTTSPAAILDTTRKLVLGDALSASSRE -QLKAWLIANTTGGARIRAGVPKDWIVGDKTGTGDKATSNDVAVLWPPGREPVLLTVYFTG -SALSRDTQSKVIADAASIVVR-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI00092F20DD ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDVRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H6UQL7_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITXSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase SHV-2 n=15 Tax=root TaxID=1 RepID=BLA2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDE0_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. TSH100 TaxID=652764 RepID=A0A4P7YKP3_9PROT ---AFAARMADLEGRTGGRLGVAMLDSGSGRLH-GWRGDERFPMCSTFKFLLAAAVLKTVD -QGKDLLDRQIPVTKADLVPYAPFSETRLNGTPTVAELCEAAMTLSDNVAANLLLPGVGNP -AGLTAFLRGIGDRTTRLDRNEPTLNTAIPGDPRDTTTPAAMVRSMQRLLVGDVLRPDSRR -LLIDWMVANKTGDKRLRAGLPAGWRVGDKTGTGTNGTANDIAILWPEGRAPLLVASYLTQ -TAEGFRQQDAIHADVARAVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI00028F5A93 ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8I448_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDGRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000CA1B93D ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERFVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX90_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGSP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI000BE9765B ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLPADWKIGDKTGTGQNGSLGDIAVIWPPNRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Kaistia soli DSM 19436 TaxID=1122133 RepID=A0A1M5LJT5_9RHIZ ---DLDSKLAEIEASLAARVGVAILDTGSKRHW-LHRADERFPLCSTFKVLAAAAILRQVD -SGTDSLSRRVIIRQGDLVDYSPVTQRRTEGKMTLAEICAAALTTSDNTAGNMMLKAIGGP -AGLTSFARSIGDDTTRLDRWETALNEASPGDARDTTTPVAMARSLQAILLGPVLSARSKK -QLATWMVANRTGDAKLRAGLPARWLIGDKTGGGNHGTMNDIAIIVPPAREPVFVAVYITE -TAASFDARNAAIASIGRAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D696469 --nTIEAQLSELEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -TKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGLSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKNRKDIIAKAAEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia sp. E1130 TaxID=2041645 RepID=A0A5F1HSI2_9ESCH ------VKVKDAEGKLGARVGYIELDLNSGKILeSYRSEERFPMMSTFKVLLCGAVLSRVD -AGQEQLSRRIRYSQNDLVEYSPVTEKHLSDGMTVKELCSAAITMSDNTAGNLLLKTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPDDERDTTMPAAIAATLRKLLTGTLLTPASRQ -QLINWMEADKVAGPLLRSALPTGWFIADKSGAGERGSRGIIAVLGPDRKPSRIVVIYTAG -SQATMDERNRQIAEIGASLIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0004ED735B ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRAAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00108406A3 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase SHV-29 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA29_KLEPN ------EQIKQSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D9IAH7_KLEPN ---AIQQKLADLEKHSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDERDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=A0A2U3D278_9RHIZ ---NIERRLAEVEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPISEEHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPMKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L2T6_9BACT ---QVQEKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTMVAAAVLKQSE -TQHDILQQKMVIKKADLTNWNPVTEKYVDKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -SNVTAFARSIGDTTFRLDRKEPELNTAIPGDERDTTSPLAMAKSLHKLTLGDALAGAQRA -QLVEWLKGNTTGGQSIRAGLPEGWVVGDKTGGGDYGTTNDIAVIWTEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella africana TaxID=2489010 RepID=A0A455M837_9ENTR ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVLLCGAVLARVD -AGDEQLERRIHYRQQDLVAYSPVSEKHLADGMTVGELCTAAITMSDNSAANLLLGTVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVVPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Proteus columbae TaxID=1987580 RepID=UPI000C1E4497 --nTIEEQLSTLEKYSQGRLGVALINTKDNSQI-TFRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVAYSPITEKHLITGMSLAQLSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIAKAAEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. ST111 TaxID=1682204 RepID=A0A0N0ZGY4_9BURK ---AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD -SGQEDLERRVVFSKSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARSNAAIANVGALIV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A2Z4YKM9_RHILE ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Class A beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A657NJH1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Class A beta-lactamase RAHN-1 n=7 Tax=Rahnella TaxID=34037 RepID=E5DWJ0_9GAMM ---SVQQQLTALEKESGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE -VKKNLLTQHVALKQSDLVNYNPITEKHLNDGMTIGELAAAALQYSDNAAMNKLIEHLGGP -HKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PEKDAKSRRDVLASAAKIVTQGy ->[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium sp. SYP-B3895 TaxID=2663240 RepID=UPI001299DA1C ---DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD -RKEEKLDRVIKYGKGDLVAGSPNTGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP -KGLTQYARSLGDATFRLDRRETELNEATPGDPRDTITPAHILKDLQKTVLGNALAKSSRD -QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSHKPILLAVYLYD -PKGTADSRNEIHRKVASLVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9H7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSPAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Herminiimonas arsenitoxidans TaxID=1809410 RepID=UPI000970442E ---AIQQELEKLEASAHGRFGVSAINTANGARV-QYRADERFPFCSTFKAIAAAAILKKSE -SNHQLLQQRVSYTKEEVEKYAPITAKHIADGMTITELCAATLQYSDNAAANFLMKELGGP -AAVTAYARTIGDDTFRLDRWEPELNTAIPGDLRDTSTPAAMQMSLQKLTLGNALALPQRE -QFVAWLQGNTTGGKRILAGVPKGWIVGDKTGTGSYGTTNDVGVIWPAKGAPIVAAIYFTQ -NEKDARPRDEVIASAARILVS-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00073ADB88 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=5 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377X909_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGLNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5D3K437_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQKIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A1V2BH63_RAOTE -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRIRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSMLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEDRNRQIAGIGETLVKHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002CA5FFD ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMRDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=A0A0T9URP1_YERIN ---SLDKQLAELEQSANGRLGIAMINTANGSKI-LYRGAQRFPFCSTFKFMLVAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKQLGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALLPAQRS -QLATWLKGNTTGDATIRAGAPADWMVGDKTGSGDYGTTNDIAVLWPTKSAPIVLVVYFTQ -REKNAKSRHDVLASATKIILS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rahnella bruchi TaxID=1510573 RepID=UPI000EA01EA5 ---SIQQQLTALEKESGGRLGVMLIDTADNSQI-AYRADERFAMCSTSKFMAASAILKESE -VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP -QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHGTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PQQDAKSRRDVLASAAKIVTQGy ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001033461F ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFLADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. CCGE1001 TaxID=640510 RepID=E8YVR7_9BURK ---AIRARLEDIQAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -RGEEDLQRRIVYSKSELVPYSPATSKHTRELMSVAQLCKAAITLSDNTAANLLLQTFGGP -AGLTAFVRSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSASRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGEHGTANDVAILWPPGRGPILVAVYLTE -TAGDAARGNAAIANVGALVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010312F7B ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYITE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=B5D619_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] class A broad-spectrum beta-lactamase OKP-A-17 n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0003BE8F2F ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082EC33 ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000669A3B7 ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLAGGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPASMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ4_9BACT -hpETLAKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVAIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. TJ1640 TaxID=2050968 RepID=UPI000D694C3C --nTIEAQLSELEKYNQGRLGVALINTEDNPQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKAAEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8YCY4_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000648CB1C ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102F9E9C ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Acidipila rosea TaxID=768535 RepID=A0A4R1KZA3_9BACT --kSFRAQMEDLEKASGGRLGVAYLDTAHGTRA-GYREDERFPMCSTFKVLAAGKILLQVD -HGREHLDRMVHYTQKEIVSYSPFTATRVGNGASLREICVAALTLSDNTAANLMLASIGGP -AAVTAFARSLGDKVTRLDRTEPALNEALPGDPRDTTSPAAMVADLQTLLLGRTLSPGAKT -QLAEWMKQCKTGGERLRAGVPADWMVGDKTGSGDRGTANDIAILWPPHASPVMVAVYLTE -AKVGPAQRNETIAAVGRAIA--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2D85B9 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLNRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf456 TaxID=1736382 RepID=A0A0Q6C6L3_9RHIZ ----FEDILARIEGRSGGRLGVAVLDTASGELT-GRRLDERFPLCSTFKTLAAAAVLARVD -GGQESLDRRIVFEREALVPYSPVTEARVGGSMSLAELCEAAVTRSDNAAANLLLRTLGGP -AGLTAHLHAFGDRTTRLDRTEPTLNEAAPGDPRDTTSPAAMVRLLAGLTLGSALSQPSRD -RLTGWLLANTTGGARLRAGLPPGWRIGEKTGTGENGTTNDAGVIWPPDGAAQVVAVYLTG -SDRPLADREAALANVAKAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q9Z4Q6_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAMLARVD -AGDKQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Acidobacteriaceae bacterium TAA 166 TaxID=278963 RepID=UPI0005BC1573 ----LADTLRSLERRSQGRLGVAVQ-LPSGESA-QLRGDERFPMCSTFKFLAASLVLERVD -QGKEHLDRAISYSRSDLVSYSPETEKHAGGSMTVAELCKAALTLSDNTAANLLLSSFGGP -PAVTAFVRSIGDATTRLDRNEPTLNEATPGDPRDTTTPNVMLRNLRRILLEDVLKPSSRQ -QLTDWMLANTTGNAKYRAGLPSGWKVVDKTGSGSRGTNNDIGVLWPPAGKPILVTSYLTA -TPLSTDAANAIHAEVARAVAVSy ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira permensis NBRC 106175 TaxID=1353532 RepID=A0A074JM51_9PROT ---RLLDAIHTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD -RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP -DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLLGDALSLESRQ -ILEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIVAIYITH -TSASMEERNAAIADLGQEIA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL54_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLI--- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. RO1 TaxID=2066034 RepID=A0A2N4SCQ0_9BURK ---QAEAQLAELERACGGRLGVAGFHTGSGARL-QHRAHERFPLCSTFKLMLAAAVLERST -TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -TAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009B3E6FE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI000BB3752A ---DAETQLAELERTCGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERST -TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKNRNDVVAEATRIAVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A36C115 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTJ0_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCVAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002775483 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMVSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=2 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00037BDB45 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase BlaA n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=UPI0005E0F0DA ---SLDKQLAALEHSANGRLGIAMINTGNCTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDAKPRRDVLASATKIILS-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1) TaxID=269796 RepID=Q2RXW2_RHORT --dALTARLIETEQRLGARLGATILDTHTGRNW-RYRAGERFPLCSTFKVIACGALLARVD -AGTEDLSQRVTFPESAVVAYSPVTKGRGEAGMTLAEICEAAITRSDNTAGNILLDRLGGP -AGVTTFARALGDTTTRLDRRETDLNEATPGDPRDTTTPEAMAKLMATLVLGKGLSVTSRD -RLTNWLLANKTGEAKLRAGLPKDWRIGDKTGGGDHGTMNDVAVVWPPGRQPLIIALYMTQ -TTASFEDRNRAIADIGRTLA--- ->[subseq from] Beta-lactamase n=3 Tax=Burkholderia glumae TaxID=337 RepID=C5AIM9_BURGB ---AARRQLAALDASFGGRIGVAALDSGSGARL-LHRADERFAFCSTFKTVLVAAVLTRAA -GDPRLLSSVIRYRRQDLVRYSPVSERHVETGMSVAGLCAAALQYSDNSAANLLIRMLGGP -AAVTAYARSIGDRWFRLDRLETDLNDAVPGDERDTTTPAAMLETLRRVTLGDALDAAGRA -RLVGWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLAVYTTR -DRKDAGYDNAAIASAARIVTAAf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Methylobacterium TaxID=2615210 RepID=A0A0Q4U2E5_9RHIZ --eNLADRFAQIEATSGGRLGIGLLDTGSGTQA-AHRGAERFPMCSTFKVLAAGAVLARID -QGEDSLDRRLRYAASEVVPYSPMSGPRADGEMTLAELCEAAVTLSDNTAANLLLGTMGGP -AGLTAQIRAFSDATTRLDRIEPDLNEAVPGDPRDTTTPLAMAQTLRRLVLADALSPSSRA -LLTAWLVGCRTGDARLRAGLPKEWRIGDKTGSGENDTANDIAVIWPPRRAPLVLTVYLTG -AKTSPEARSATIASVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0B5NNS5_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKRATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella oxytoca TaxID=571 RepID=Q5DUJ7_KLEOX ---AIQQKLADLEKHSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009B586AB --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000365D8C0 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0007EA32CA ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LS80_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAGNLLLTTVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTC6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAVTLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. viciae (strain WSM1455) TaxID=755176 RepID=J0BUK4_RHIL1 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCG -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar vazensis TaxID=180867 RepID=A0A243D5L1_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. DSM 27956 TaxID=1955699 RepID=A0A231RKC5_9BACI -----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVLQQNS ---LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP -DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT -ILTDWMRGNTTGDELIRAAVPMGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR -DTEDAAYDNELIAKAAKVALKEf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2C5252 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVVYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N0A9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWVVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Shewanella fodinae TaxID=552357 RepID=A0A4V2RSE7_9GAMM -hqAIQQQLSALEATTGGRLGIALIDTGTNARL-LYRGDERFPMCSTSKVMVVAAVLKQSE -QQQTLLTHKLAIKPTDLVNYNPVTEKHVNSEMTVAELSAAALQYSDNTAMNKLLSLLGGT -ARVTQFARDIGDQVFRLDRIEPELNTAIPGDERDSTSPLAMAQSLRQLTLGSALADPQRL -QLVEWLKGNTTGAASIRAGLPESWVVGDKTGSGEYGTTNDIAIIWPEAHAPLILVTYFTQ -QQQDAKARKDVLAAATQIVMRH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL50_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRXD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLIKH- ->[subseq from] Beta-lactamase SHV-5 n=22 Tax=Bacteria TaxID=2 RepID=BLA5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q4TVR4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q5YCY3_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2W6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D9559DF ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRTDERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. V-88 TaxID=1938744 RepID=A0A1U6JS66_9BACI -----AHKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVLQQNS ---LDELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEELGGP -DGFENGLRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPDSKRT -ILTDWMRGNTTGDELIRAAVPMGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR -DTEDAAYDNELIAKAAKVALKEf ->[subseq from] Beta-lactamase n=1 Tax=Morganella morganii TaxID=582 RepID=Q6EH43_MORMO ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAL-GPDGKPSRIVVIYTTG -SQATMDEANRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY8_KLEPN ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKALLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=unclassified Photorhabdus TaxID=2620880 RepID=A0A329WKE7_9GAMM ---SLHKQLAELENSIKGRLGVALINTANGQEI-QYRGDERFPFCSTFKLILVAAVLHKSM -SQSELLAKHIHYRESDLLSYAPIARKNIHQGMSVTQLCAATVQYSDNTAANLLIKELGGL -EAVNRFVQGIGDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVLAAPQRE -QLIAWLKGNTTGDASIRAGVPAGWVVGDKTGMGDYGTTNDVAVLWSPKGVPVVLAVYFTQ -PQQDAESRRDVLASATRLVMAH- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=C3GJ41_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKRATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9I0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADECFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3KE68_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRXD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPXAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenoliruptrix BR3459a TaxID=1229205 RepID=K0DV60_9BURK ---AIRARLEDIQAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -RGEEDLQRRIVYSKSELVPYSPATSKHTRELMSIAQLCKAAITLSDNTAANLLLQTFGGP -AGLTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSASRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGEHGTANDVAILWPPGRGPILVAVYLTE -TAGDAARGNAAIANVGALVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A0A0M3R8A6_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter pasteurianus TaxID=438 RepID=Q0VJ94_ACEPA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIE------- ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F21C5 ----LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKVRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRS------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F21C5 ------------------------------------------------------------- -------------------------------------------------AANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000AD04548 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVPRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Cobetia sp. ICG0124 TaxID=2053669 RepID=UPI000FDA4F69 ---------QEIEQRVGARLGVTVLDTANGRRV-SWRGDERFPMSSTFKVLACGNLLSRVD -ARQESLSRKVEIRPADLVTYSPVTERQVEGDMTLAALCRATITTSDNTAGNLILDAIGGP -VGLTNYLRTLKDDITRLDRRETALNEATPGDPRDTTTPDAMASTLQRLLLGEALSEASRL -TLQGWMLANTTGSDKLRAALPDDWQIADKTGGGGHGTNNDIAIIWPPNHAPLIVAVYLTE -SEAERAVRDAAIADVGRLLVS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI70_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQPGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 77 TaxID=1101192 RepID=UPI00037A6602 ----LADRFARIEQASGGRLGIGLLDTGGGAPV-AHRGGEPFPMCSTFKVLAAGAVLARVD -RGEDSLDRRLRYTLGEVVAYSPMSGPRAGGEMTLAELCEAAVTVSDNTAANLLLGTMGGP -AGLTAQLRDFGDATSRLDRTEPDLNEAVPGDPRDTTTPLAMAETLRRLVLGDALSPVSRA -LLTAWLVGCRTGDARLRAGLPKEWRIGDKTGSGEYDTANDVAVIWPPRRAPLVLTVYLTE -AKASPEARSAAIASVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013C578F6 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAASVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UI74_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus oleronius TaxID=38875 RepID=UPI000990C629 ---STNRKFAQLEKKFDARLGVYAIDTGTNKTI-TYRPDERFAYASTYKALAAGAVLQQYS ---MAQLDEVIHYSKDDLVSYSPITEQHIDTGMSLKEICEAAIRYSDNTAGNLLFHKLGGP -SGFEESLRQIGDHVTIANRFETELNEAIPGDLRDTSTPRALATSLKAFTLSDLLPAKKRV -ILANWMKGNTTGDKLIRAGAPKGWEVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYNDELIARAAKLVFK-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A7LIT2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Oxalobacteraceae bacterium AB_14 TaxID=1158293 RepID=UPI000368B126 -----ASLLAKLEGESGGRLGVAALNTADGRQL-LHRADERFPFCSTFKMMLSAAVLAREP ----ALLRKRVRYTRKDLVTYSPVTEKHVGTGMTVAALCEATLQTSDNTAANLLMQLIGGP -AAVTAFARSIGDMEFRLDRIETALNSALPGDPRDTTTPASMAESLHKLLLGDGLGVAQRK -QLKDWMLGNTTGDTRIRAGVPSASLVADKTGTGDYGSTNDIGVIWQPGKAPIILVIYLTQ -PGKDDKARSEILAEATRIVVEAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. Bc-h TaxID=1943632 RepID=A0A1V9UNN3_9PSED ---SIERQLAALERRHGGRLGVAILDTGTQRLI-SHRGDERFAMCSTFKALTAAHVLARVD -RKEEDLSRVIVYGQDQLVTYSPVTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP -KGLTAWLRTIGDQTTRLDRREPELNENRPGDLQDTTTPIAMLHSLRTLVIGDVLSGASKV -QLIAWLVSNKTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAIIWPTGRPPLIVTVYYSE -SKASSEQINSLMAEVGRLVAK-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q2YHZ4_KLEPN ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] class A extended-spectrum beta-lactamase OXY-1-6 n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI000016F82E ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVPVTYFTQ -PQQDAKSRKKVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Enterobacterales TaxID=91347 RepID=B8YHZ8_KLEPN ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus obstructivus TaxID=1914540 RepID=A0A1L8ZP65_9BACI ---STNRKFAQLEKKFDARLGVYAIDTGTNKTI-TYRPDERFAYASTYKALAAGAVLQQYS ---MAQLDEVIHYSKDNLVSYSPITEQHIDTGMSLKEICEAAIRYSDNTAGNLLFHKLGGP -SGFEESLRQIGDHVTIANRFETELNEAIPGDLRDTSTPRALATSLKAFTLSDLLPAKKRV -ILTDWMKGNTTGDKLIRAGAPKGWEVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYNDELIARAAKLVFK-- ->[subseq from] Beta-lactamase n=2 Tax=Bordetella bronchiseptica TaxID=518 RepID=A0A5A4M9B6_BORBO ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALHPASRQ -RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase SHV-46 n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=BLA46_KLEOX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLNSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00103A6392 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVLAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I6N3_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQPERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTTFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00035CC86D ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI000D19893C ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGP -KQLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTC4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGLGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014420E9C ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENLDRRVNYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005E764A0 ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPVKGAPLVLVVYFTQ -LKKEAEPRRDVLAAATKIVLAH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144101D8 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPLSEKHAGTDMTLAELCEAAVKVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGRERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATASAKELNPVFAEVGRMIVE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D19F156 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGVRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAT9_9ENTR --dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q8GM80_KLEOX --dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter vibrioides TaxID=155892 RepID=A0A290MLG6_CAUVI ---DLTSRINALEKASGGRLGVAVLDTHTGRRF-AWRGDQRFRMCSTFKTPLAAAILRRVD -QGRERLDRRIRYGRDVLIAHSPAVDKHLGQGMTVGALCEATITLSDNAAANLLLDALGGP -SALTRFLRAIGDETTRCDRREPELNGGAPDDPRDTTTPVAIVETWRTLLLDDVLTPASRH -QLAEWVVANRTGDRRLRAGLPRGWRVGDKTGSDGRAITNDVAIAWPPGRKPLLLAVFHDQ -GAPDDAARNAVLADTARAVVA-- ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002184FA8 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDHWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0006C39AD4 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DEKGAAYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6Z9I8_ECOLX ---DVQQKLAELERLSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTATPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE4B8D4 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E7CER3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMLSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax cavernicola TaxID=1675792 RepID=A0A3A1WEF3_9BURK ---DAEAQLAELERACGGRLGVTGFHTESGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVREMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDSTFRLDRMEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGAPQRD -QMREWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLAVYLTF -PDKDAKNRNDVVASATRIAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar mexicanensis TaxID=180868 RepID=A0A242WEJ4_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010827373 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMLSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 6HR-1 TaxID=1141884 RepID=A0A4Z0NKY3_9RHIZ ---DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAVAAAAVLARAD -TGQDDLNRRITYTRDDILSYAPVTAKHVETGMTLAELCAAAVVWSDNTAANLMLATLGGP -EGITAFARAHGDTVTRLDRTEPTLNTAIRGDLRDTTTPAAMVGLLDTLLLGQALSAASRA -RLTGWMQESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIARSf ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A444IN82_RHILE ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus halotolerans TaxID=260554 RepID=UPI000BFF07C6 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000A111E8C ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00122D23A5 ------------EDQLGARVGYIELDLNSGKILeSFRLEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E414C6 ----LGNQLAELERNSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPGLLDKHIKYHESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ASVNAFARSIGDQVFRLDRLEPDLNTALPNDPRDTTTPAAMADSMNKLVLGDALPAAQRE -QLALWLKGNTTGANTIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVLVIYFTQ -REKDAKPRRDVLAAATKIVLSH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus halotolerans TaxID=260554 RepID=UPI0009F1B4AA ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00040AEAFF --dDVTERLRQLEERTGGRLGVAVLDTETNISF-VHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2R2IPE8_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI00131F6698 ------HKFMQLEKKFDARLGVYAIDTGTNQTL-AYRPDERFAYSSTFKALAAGLVLKQNS ---MDELDEVITYTRDDLVTYSPITEQYVDTGMTLREISDAAIRYSDNTAGNLLLQELGGP -DGFENALRQLGDHVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLLEDKRA -LLTDWMRGNTTGDELIRAGVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRAPIIIAILSSR -DTEDAAYDNELIAKAAKVVLKEf ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. A3 TaxID=1337054 RepID=A0A0P9DTZ5_9BACL ------DEFIQLENKFGARLGVYAIDTGTSRTI-AYRPEERFAFASTYKALAAGAVLQQSS ---IANLDKVITYTKEDLVTYSPITEKHVETGMTLRDICDAAIRYSDNTAGNLLLKELGGP -KGFETVLKKIGDNVTTSARFETELNQAIPGDTRDTSTPIALATTLQAFTVGDVLSTDKRK -LLTDWLRGNTTGAKLIRAGAPEGWQVGDKTGAASYGTRNDIAIVWPPNRDPIIIAILSSR -DKQDSAYNDDLIAQAAKIAMDAf ->[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A209AJR3_YERFR -----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPAAQRE -QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ -REKDAKPRRDVLAAATKIVL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A292G2V0_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAES---------------- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=UPI0007853550 -hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -TKQDAPWNSETIAAATRIVVEAw ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Leaf177 TaxID=1736287 RepID=A0A0Q5PHC1_9BURK ----VGEELARIEARSGGRLGVSILDTGSGKRA-GLRADEAFPMCSTFKFLAASFVLARVD -QGQEDLKRKIVYSKSDLVEYSPVTQHHTGPALSVGDLCAAAITLSDNTAGNLLLASFGGP -PALTAFLRTLGDQFTRLDRNEPTLNESTPGDPRDTTTPNAMLANMRTLLLTDRLSVSSCA -QLRDWLIANQTGGKRIRAKLPKDWRVGDKTGTGSHGSTNDIAIIWPPGRPPLLVSAYLTQ -TNAETARREAAIADVGKLLV--- ->[subseq from] Class A beta-lactamase n=8 Tax=Rhizobiales TaxID=356 RepID=A0A222H047_RHIML --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK -RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKB6_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D4QFM2_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDGVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDC6324 --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK -RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DD34A4F ------EQIKQSESQLSGRVGMIEMDLASGRXLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVXRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Rhizobium leguminosarum TaxID=384 RepID=C6ASM4_RHILS ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTNWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLNTLGNLTLGSVLAEASCD -RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5VCA8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMISTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A0G4QB59_PROVU --nTIEAQLSELEKYNQGRLGVALINTEDNSEI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKAAEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B8Y883_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIELw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5Q3M162_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Massilia umbonata TaxID=864828 RepID=A0A4P8HM84_9BURK ----ATGSFAAIERDLKGRLGVAVIDTATGTAS-GHRLDERFPMCSTFKALLAAQALARDA -REPGFAERRLRYAKADLVGHSPVTGKHVDTGMTVAELCAATVQYSDNAAANTLMKELGGP -AGLTAFMRGIGDTTFRLDRWELELNTAIPGDERDTTTPLAMARTLQKLVLGDALPAPQRQ -RLKQWLVGNTTGDRRIRAAVPANWQVGDKTGTGAYGVTNDIGIVFPPGRAPLVVVVFTHQ -PDKDADSREDVVVAGAR------ ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002A54C26 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9GMT4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVE -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia rhynchosiae TaxID=487049 RepID=A0A2N7WND9_9BURK ---AIRARLKQIEAESGGRLGVSIIDTASGLHA-GLHADERFPMCSTFKLLTAGAILSRAD -RGEEDLQRRIVYSQSELVSYSPATSKHTRERMTVAELCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSSSRA -KLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVAVYLTE -TAGNAARCNAAIADVGALVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q7WYH2_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQL -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTC5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGWALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=UPI0007F8AE3B ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRVARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A2J0YUH7_RHIML --eDVTERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEKLERRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -EGLTSWLRSIGDETTRLDRTEPELNEARKGDPRDTTTPAAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIAVAWPQGRGPILICVYMGE -AKAPLDDLNPVFADIGSIVAD-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0007D0C6F0 ---AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEP--NTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGTGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM3983 TaxID=1038867 RepID=UPI0003FE0F03 ------KAIEQLELKSGGRLGVSVLDATTGIPI-HHKGDERFPMCSTFKVLASAAILKNAG -SKLELLERRVRFEQADIVENSPVTREHVGGEMSLRELCDAAITMSDNTAGNALLNNIGGP -AGLTSFARSLGDKMTRLDRTETELNEATPGDPRDTTTPNAMAANLKRLLLGDALLPEGRD -QLAKWLIANKTGNSRLRAGLPQGWRVGDKTGAGEHGTTNDVAIVWPPERSPLIVAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W5VPT5_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASL---- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1Z1VQL0_KLEPN -----LEQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A1T3V451_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=D5LGB4_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAELDQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=UPI000287A7D0 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASLQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0011C8A891 ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQHIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain 03BB102) TaxID=572264 RepID=A0A125U4Q9_BACC3 --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5VXW0_9BURK -------------AEAGGRLGVMALDTGTGSRW-AWRADERFPACSTFKVLAAAAVLARSV -DDAGLLTRRVRYPASELVTYSPVTEKHLADGMTIAELCAAALQYSDNTAGNLLLRQIGGP -AGVTNYARSIGDSTFRLDRWETELNTAIPGDPRDTCTPAGMAHNLQRLLLGDALAPAPRA -QLQAWMRGNTTGATRIRAGVPAAWAVADKTGSGDYGSVGDIGVTWRPDAAPIVLALYFAQ -ATKDASMRSDVLAAAARIVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2S9HMF8_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5P8NAY5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWHADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAKRNQQIAGIGAALIEHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI001402FDFB ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZI82_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNRTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003672711 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf85 TaxID=1736241 RepID=A0A0Q4UAD0_9RHIZ --rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAALARVD -RGEDGLDRRLRYELREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP -AGLTGHIRRFGDATTRLDRTEPDLNEAAPGDPRDTTTPRAMAETLRHLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG -ARTSSEARSATIASVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4RRV8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRCVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A640LDP3_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia sp. IP36721 TaxID=2161716 RepID=UPI000EB3F433 ----LSEQLTALEEKAQGRLGVSLINIQSGKEL-QYRGNEAFPFCSTFKLVLAAAILRQSM -SQPVLLEKHITYSEADLLSYAPIARENLGKGMTIAALCAAALQYSDNTAANLLIQQLGGL -EGVNKFTQSLGDTAFRLDRWEPELNSAIPGDPRDTTTPSSMAALVKKIQFGDGLAPAQQQ -QLAQWLKGNTTGNASIRAGVPADWLVGDKTGSGDYGTTNDVAVLWPPTGAPLILAVYFTQ -HKKDAESRRDVLAEATRIILAQy ->[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2A7DAM0_BACAN --qATYKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKEFTVGNALPDHKRN -ILTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKDAPYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. A9 TaxID=1284352 RepID=UPI0003721328 ---SLASSFRALEQQHQARLGVYAIDTGTGKVV-AYRHNERFAFASTYKALAAAAVLQQNS ---IADLDRVITYSAKDLVEYSPVTEKHVDTGMTLREICEAAIQYSDNTAGNILFQELNGP -AGFQQALRQLEDRTTRSERIEPELNAAVPGDPRDTSTPRALARDLRLFTTGKVLSQDKRQ -LLAEWMKGNTTGDDLIRAAAPKGWIVGDKTGSASYGTRNDIAVVWPPGRSPIIITVLTGH -TDKNAKVDNELVAKAAKMVFD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A1J9W355_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAITTNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I6N7_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9F918_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX87_KLEPN ------EQIKLSESQLSGRVGMIEMDLASSRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Yersinia entomophaga TaxID=935293 RepID=A0A3S6EXT5_YERET ----LSEQLTALEEKAQGRLGVSLINIQSGKEL-QYRGNEAFPFCSTFKLVLAAAILRQSM -SQPALLEKHITYSEADLLSYAPIARENLGKGMTIAALCAAALQYSDNTAANLLIQQLGGL -EGVNKFTQSLGDTAFRLDRWEPELNSAIPGDPRDTTTPSSMAALVKKIQFGDGLAPAQQQ -QLAQWLKGNTTGNASIRAGVPADWLVGDKTGSGDYGTTNDVAVLWPPTGAPLILAVYFTQ -HKKDAESRRDVLAEATRIILAQy ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum rhizosphaerae TaxID=346179 RepID=UPI00067D026F ----VVSRLAKLEASVGGRLGVDIIDSATQRRW-GYRAGERFPMCSTFKFLASAAVLKRVD -AGQEQLERRIIYGNDVLVSYSPTTSKHVGGNLTLGQLCEAALTLSDNTAANLILKSLGGL -EPFNKFIKSLGDRQTRLDRFETELNTAIPGDLRDTTTPAAMSDNLQRILLGDVLSPSSRE -QLIAWMRSNKTGDRRVRAGMQPGWSVGDKTGSGDYGTTNTIAIIWPPQGKPLLASVYLTR -TKAPEEQRNSVLAEVGKLIV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R634 TaxID=1764274 RepID=A0A246SJ26_9RHIZ ---NVERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVSYGKEKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSCS -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYITE -ATVPAKDLNPIFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A9CSQ3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALSGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B2BII5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALSGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus namnaonensis TaxID=1851568 RepID=A0A1B8YD02_9GAMM ---SLHKQLTELENSTKGRLGVALINTENGQEI-QYRGDERFPFCSTFKLILAAAVLHKSM -SQPELLAKHIHYRESDLLSYAPIAHKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL -EAVNRFTQGIGDPAFRLDRREPDLNSAIPGDLRDTTTPAAMAASVKKIVLGEVFGASQRE -QLIVWLKGNTTGDASIRAGAPAGWVVGDKTGAGDYGTTNDVAVLWPLKGAPVVLAVYFTQ -PQQDAESRRDVLAAATRLVMAH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDA97F5 --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLARTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E90138 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAVAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDD9_KLEPN ----------ESESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=A0A5P2MT43_BORBO ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -QLADWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS015802 TaxID=2033486 RepID=A0A2A8VDE6_9BACI -----NQKFMQLEKKFDARLGVYAIDTGTNRTV-VYRPDERFAYTSTYKALAAGAVLQQHS ---MDELDEVITYTKDDLVTYSPITEQYVDTGMTLREICDAVIRYSDNTAGNLLFQELGGP -DGFENALRQIGDHVTEADRFETELNSAIPGDIRDTSTARALATNLKAFTVDDVLPVDKRT -ILTDWMRKNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSSR -DTKDAAYDNELIAKAAKVVLNSf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium etli TaxID=29449 RepID=UPI00057FBAC9 ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGHIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A483KAC9_9ENTR ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLHQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNSKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00112A2B1F ------EAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG -SKLEALERRVRIEQGDLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTSFARSLGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD -QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAVYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI000290600C ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI000461EDFB ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=E5KCK0_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEI-------- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0011A43884 ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDTLAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVIYFTQ -LKKEAEPRRDVLAAATKIVLAH- ->[subseq from] class A beta-lactamase n=1 Tax=Candidatus Fukatsuia symbiotica TaxID=1878942 RepID=UPI00093528D5 ---SIQEKLSELEKISGGRLGLFAINTANNLTV-QYRAVERFPVTSTFKVLAVAAILKQSV -TDRQLLQQRITYNPKDLVSYSPITEKHLG--MTVEELCAATIQYSDNTAVNLLMKLLGGP -KAVTEFARSIGDHTFRLDRWETDLNSAIPGDLRDTSTPVAMAKSVQRLVLGDALPPAQRE -KLQVWLKGNTTGDASIRAGIPEGWVVGDKTGGGDYGTTNDIGVLWPPTAAPIVVAIYFTQ -NEKDAQTRKDVIASATRILISAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6YE63_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVTAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTASPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E2C92E --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=2 Tax=Marinobacter lipolyticus TaxID=209639 RepID=R8AY12_9ALTE -hnSLIKTVESIASEIEARVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD -AGQENLERTVSFSESDLVTYSPITEKYAGGQMTLSDLCEAALTRSDNTAANLILRSLGGP -EKVTSFARRLGDDVTRLDRWETELNEAAPGDNRDTTTPNAMVKNLQSLLLGDALSGKSRE -QLHDWLKRNQVADGLFRAVVPEGWIVADRTGAGGFGSRSITAIIWPPERQPIVVALYLTQ -TEASFSERNEAIAEIGEAIV--- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GF08_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=K7U492_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A384X512_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWHADERFPMMSTFKVVLCGAVLARMD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A329F905_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGALLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0011197AF1 ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=F6K6C7_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY74_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=A0A2U8QB09_9BRAD ------EAIKQLELKSGGRLGVSVLDTMTGVPI-HHKGDERFPMCSTFKVLAAAAILKAAG -SKLEALERRVRIEQADLVEYSPVTREHIGGEMTLRELCDAAITRSDNTAGNALLKNIGGP -AGLTGFARSLGDDITRLDRTETGLNEAKPGDPRDTTTPNAMAANYRRLLLGDVLLPEGRD -QLGQWLIANKTGDTRLRAGLPQGWRVGDKTGAGENGTANDVAIVWPPKRSPLIIAIYLTG -ASLDPNGRNDVIASVGREVGKAf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium loessense TaxID=158890 RepID=A0A1G4PDG6_9RHIZ --dDIEHRLAELEKRTGGRLGISVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYNQEKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP -KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE -KLIEWMLANTTGDARLRAGLPRAWKVGDKTGTGDNGSAADIAIIWPKGRGPILVTTYIAE -ATAPVKELNPVFVEVAKIVA--- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M9T8M5_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAASQRQ -QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q1WBU3_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALI--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bradyrhizobium sp. LMTR 3 TaxID=189873 RepID=A0A1B9YX55_9BRAD --qRLIDEIRRLERGSGGRLGVCVLDTATDTRH-AHRGDERFPMCSTFKMLAASAILARVD -AGKEQLTRRVTFDASALIVYSPVTEKRVGGDMTLAEICEAAVTLSDNTAGNLLLAGIGGP -PGLTAFVRSLGDQVTRLDRDEPSLNEALPDDIRDTTTPNAMASNLQALILGKALSAASRE -QLTAWLVANKTGDARLRAGFAKDWRVGDKTGTGARGTNNDVAVIWPPGKAPIVITAYLTG -ATVSAAQQNATLASVARAVS--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000B0DC1CF ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPSDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=R4RZD7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQHLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium plurifarium TaxID=69974 RepID=A0A2T3ETP8_MESPL ---DVMERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEELDRRITFGEEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEATKGDPRDTTTPAAMLDTLGKLVLGSVLSEEGRK -QLIDWLVANKTGDSRLRAGLPKDWRIGDKTGTSMTGAASDIAAAWPRGRGPILICVYTGE -AKAPLDDVNPVFADIGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=[Empedobacter] haloabium TaxID=592317 RepID=A0A5C7CEW2_9FLAO ------SAFAALERKFKGRVGVAAIDTASGKVI-GNRQDERFPFCSTFKTIVAAAVLARSA -TEPGFLGKRLRYTQADIKPHSPVSEKHVEAGMTAAELCAATIQYSDNAAANILMRELGGP -AAITAYARTLGDTTFRLDRWETELNSAIPGDERDTTTPLAMARTLQKLLVGDGLPPAQRQ -QLKDWMVGNTTGATRIRAGVPKGAVVADKTGTSGYGVANDMGVIYLPQRAPIVLVVFTHG -ATEQAEARSESVAEATSVALR-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000B414920 ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0007CD0252 ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F54395A ------------ESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. TaxID=1872122 RepID=A0A519IFX5_9BURK ------EALARIEASVGGRVGVAVLDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD -QGQDKLDRRITYAKKDLVTYSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP -AALTAYVRSLGDSITRLDRNEPALNEAKPGDPRDTTTPQAMVHCIQALALGDALSPASRE -KLQGWLLANKTGDRRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPHGRKPVVVSCYLTG -GEAPPEQREAAMAEIGALVAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3MVZ3_9BURK -----SARLAALESESGGRLGVSVREPGRAAPW-GHRQDERFPMCSTFKLIAASGVLALSA -SDTGLLDRRIAYTKAELVSYSPVTQQHAGDGMTVAQLCAAALQYSDNTAGNLLIRLLGGT -EAVTAYARSIGDNAFRLDRWETELNTAIPGDWRDTTTPAAMAMSLERVALGDALGAPQRA -QLVAWLRGNTTGAARIRAGVPADWQVGDKTGGGDWGTTNDVAVLWPPGRPPLVVAMYFTQ -PQQDAAARSDVLAAAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. DrBHI1 TaxID=2006091 RepID=A0A246GWL9_9PSED -hdPLRQAMQQLEAASGSTIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -TKQDAPWNSETIAAATRVVVEAw ->[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium subtsugae TaxID=251747 RepID=UPI0006411387 ---SAAARLAALEADFGGRLGVCALDTASGAEL-GHRVGERFPFCSTFKAMLVGAVLARSA -KQPGLLAERIHYARRDLVEYSPRTEPHLADGMTVAELCAAAVQYSDNSAANFLLKLLGGP -AALTAYMRSIGDESFLLERWEPELNRAVPGEARDTSTPQAMAQSLRRLALGDALAPHAQR -QLVEWLRGNTTGAEKIRAGVPAGWVVGDKTGNGRYGSSNDIAVLWPPGRAPAVLTVFTTQ -ALEDAKQRHQVVAAAARIAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. Pch-P TaxID=2082385 RepID=A0A5Q3HAM9_9BURK ---AVTARLQAIERESGGRLGVSILETGNGARW-GYRAGERFPMCSTFKLLAAALILHRVD -KGQEQLDRKIIVKPSDIITHSPTTKQYVGTQITIAQLCEATVTLSDNAAGNLLLESFGGP -AGLTAYTRSLGDTMTRLDRNEPSLNEATAGDKRDTTTPDAMVSTIQKIVLGTALSEASRK -QMTQWLLDNKTGDTRLRALLRPGWRVGDKTGTGGHGSTNDVGILWPPGRAPVVVAAYLTG -TSRPIAQREATLAKVGELAA--- ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A367W4M1_9PROT ---RLLDAVQTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD -RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP -DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLLGDALSLESRQ -ILEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIAAIYITQ -TSASMEERNAAIADLGQEIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus genomosp. 5 TaxID=1311788 RepID=UPI000D68C69C --nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKVSE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVIYFTQ -QEQDAKYRKDIIAKAAEIVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=V5N0U5_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMTDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7B649C ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRISYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00050C8427 ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Reyranella sp. TaxID=1929291 RepID=A0A521QRY0_9PROT ------SALRELERRNGGRLGVALLDTASGRRV-AHRGDERFPMCSTFKFLAAALMLARVD -RGEERLDRRVVFAESDLVPYSPATKEHAGPGMTVDAICAAAMTLSDNTAGNLMLASFGGS -AGLTAFVRGLGDPMTRLDRIETELNEGAPGDPRDTTSPLAMLGTMQKLVAGNVLSAGSRE -RLIGWLVANKTGDKRLRAGLPASWRVGDKTGTGGNGSANDIAVAWPPGRAPVFIAAYYTG -STISDEARSAAIAEAGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8YW28_RHILE ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Metallibacterium scheffleri TaxID=993689 RepID=A0A4S3KLR3_9GAMM ---RLQRQFARIEAASGGRLGVAMLDLRTGLHA-SHRGGERFPMCSTWKVLAVAAMLQRVD -AGQERLDRRIRFDAHQLVSWSPVTERHVGGEMRVDALCAAALEISDNTAANLLLEALGGP -AAITRFARGLDDRVTRLDRYETALNEATPGDPCDTTAPDAMAGDLRRLLLGDALHADSRA -RLLAWMEACRTGDGKLRAGVPAHWRVADKTGSGGYGSSNDVGLLMPPGQRPVVVAVYLTQ -TRVAEAQRHAAIAAVARAIVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4C1F70 --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAKAAEVVVNAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE6B231 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGFGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudorhodoferax sp. Leaf267 TaxID=1736316 RepID=A0A0Q4Y0N9_9BURK ---AARAAFTRLEADLGGRLGVFAIDTADGATL-GHRADERFAMASSFKAILAAAMLARSV -QEPALLQRLVRYTERDLLPHSPVTGQHVAQGMTVAALCAATVQYSDNAAANLLLEVLGGP -AALTAYTRTLGDTQFRLDRTEPALNSAQASDPRDTTTPQAMARTLRTLVLGDALPAPQRA -QFKDWLLGNTTGGARIRAGVPAGWAVGDKTGTGNHGAASDIGVVWPPGRAPLVVVVYTWR -EAADAKAREDVIADATRVVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0F4D8 ---DLAAAFKTLEEKTGARLGVSAHDTGSDSRI-EYRENERFAMCSTFKFLASAAVLARVD -QKQEQLDRMILIKKSDLVAYSPVTEKYVGKPMSIEAICEAAVTLSDNTAGNLMLDTLGGP -KGLTKYARSLGDATFRLDRWETELNEAKPSDARDTITPAAILKDMQKTVLGDALSKSSRD -QLVEWLLGNKTGDKRLRAGLPKDWSVGDRTGTSDSGMANDLAVIWPPDRKPILLAVYLYD -PKGTADSRNTIHKKVAALVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus genomosp. 4 TaxID=1311818 RepID=UPI000D68A444 ---TIEEQLAILEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE -KQAGLLNNYITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQNAKYRKDVIVKATEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q93A78_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRCEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEQNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7ANY8_KLEPN ---ETLVKVKDAEDQLGARVGYIXLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXXXXSLIKHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010135F69 ---------QQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3S8XG03_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSAFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLCKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Carbapenem-hydrolyzing beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M9T6C6_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010319F6B ----IDLRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 5 TaxID=1395608 RepID=UPI000B9E0880 -----QRLLARLEARDGGRLGVSVLDTGSGWAL-AHRSDERFPMCSTFKWVAAAAVLARVG -RGQDSLDRHIRYGATDLVPYSPVTKPQVAQGMTLGALCEAAVVWSDNTAANLMLSTLGGP -PGITAYARSQGDDQTRLDRIEPALNEAQPGDPRDTTTPQAMLRLLRRVLLEGGLEAPQRD -QLTAWLRGCRTGDTRLRAGLPADWVVGNKTGAGEHGTNNDVAVIWPPRGAPILVTAYLTN -SPASRDAQNALLAETARIVAH-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD8_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHSMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio fructosivorans JJ TaxID=596151 RepID=E1JVD7_DESFR ---SLTRQIASLEQRAHGHLGVALLNASGALAF-TYRGQERFPFCSTFKFLVAAAVLQKSL -ADPALLDTRIRYGEGDLLSYAPVTRKNVARGMTVAELCAAALQVSDNTAANLLIRQLGGT -RAVNAFARSLGDTAFRLDHLEPDLNAAIPGDPHDTSTPEAMARSMREIALGKVLGPAQRD -RFVAWIKGNTTGDTSIRAGVPPGWTVGDKTGGGAYGTSNDVAVIWPPHGKPIVLAIYFTQ -QQKDAPARRDVLADAARLVVKHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZM32_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKPIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. Acro-835 TaxID=2608357 RepID=UPI00141D8EA2 --eKIQQQLHQLETQSGGRLGVVLIDSADNTQI-RYRANERFPMCSTSKVMAVAALLQQSE -KNSAVLQQRLAINASDLVNYNPITEKQVGSSMTLAELSAAALQYSDNAAMNLILDHLGGP -AKVTAFAKEMGDSDFRLDRKEPELNSAIPGDPRDTTTPLSMAHSLQKLTLGKALAAPQRE -QLVQWMKGNTTGRQSIAAGLPSGWKVGDKTGSCDYGGTNDIAVIWREKGAPLILTTFFVQ -PQPDAKSRRDVLAAAAKIVTAQy ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDLVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae (strain WSM419) TaxID=366394 RepID=A6U720_SINMW ---DVTERLRQLEERTGGRLGVAVLDMETNISF-GYRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG -QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE -AKAPVSDLNPVFAEIGKIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C5C1Z0_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=Q6RCP6_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0012373A51 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGXLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium variabile TaxID=298794 RepID=A0A0J6T0T2_9RHIZ ---DAAARLAQLERRDGGTLGVEVRDTATGRRF-GHRADERFPMCSTFKALAAAAVLARAD -QGKEDLNRRISYGRDDLLSYAPVTAKHVEAGMTLAELCAAAVVWSDNTAANLMLTTLGGP -EGITAFARAHGDTVTRLDRTEPTLNTAIAGDVRDTTSPAAMVGLLDHVLLGRALSAESRA -RLTGWMHESPTGLKRVRAGLPAEWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIARSf ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI000E6BF6C5 ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLATAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI00037E0EC2 ---DVTERLRQLEERTGGRLGVAVLDMETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG -QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE -AKAPVSDLNPVFAEIGKIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4Q9ZPF8_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010401029 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAELGRMVVE-- ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0002184FA7 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDSWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax anthurii TaxID=78229 RepID=A0A328YWW9_9BURK --eSLEQALGRIESAVGGRLGVAVLDTQTGRQA-AHRGDERFPLCSTFKLLLAAQVLHRVD -QGQERLDRRVTYRRADLVEYSPATASHADAGMTVGQLCEAAVTLSDNTAANLLLASQGGP -LALTAWLRTLGDGHTRLDRGEPELNDVPPGEVRDTTTPWAMVRTVQAIALGPALTEAGRE -QVRAWLVGNRTGDKRLRAGMPAGWRIGEKTGTGPRGTSNDAGLFWPPGRGPVMVSCYLTG -SPASAERRDAAIAEVGALAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010327588 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GFRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPAKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0011A94589 -----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPAAQRE -QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPAQGAPIVMVVYFTQ -REKDAKPRRDVLATATKIVL--- ->[subseq from] Class A broad-spectrum beta-lactamase OXY-4.2 n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAS4_9ENTR --dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVFKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=H2ETE8_ECOLX ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD -TPATIAERNQQIAAIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Serratia rubidaea TaxID=61652 RepID=A0A447QJ63_SERRU --pATLDTIKDAESRLHGRVGYAELDLASGNMMdSYRADERFPMMSTFKVILCGAVLARVD -AGQEQLDRRIRYRQNDLVEYSPVTEKHLAEGMNVGELCHAAITMSDNTAANLLLSTLGGP -SGLTAFLRKTGDSVSRLDRWETALNEALPGDERDTTTPESMARTLHNLLTGDALSAESRR -QLMRWMEMDNVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG -TKATMDERNKQIADIGAALINHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus 03BB108 TaxID=451709 RepID=A0A0B5ZH41_BACCE --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf85 TaxID=1736241 RepID=UPI000B03100F --rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAALARVD -RGEDGLDRRLRYELREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP -AGLTGHIRRFGDATTRLDRTEPDLNEAAPGDPRDTTTPRAMAETLRHLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG -ARTSSEARSATIASVARAVA--- ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000576766 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWATELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C3FJ81_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0000519015 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMGTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase SHV-1 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000576765 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWATELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9K5K0_KLEPN ---DVQQKLAGLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSPAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRHVLA---------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZA4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSAFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TSASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. TaxID=376 RepID=A0A525IEQ0_BRASZ ----AEALIAVIEQAAGGRLGVAVIDSGSKRSI-GHRADERFPMCSTFKVLAAGAVLKRVD -AGTERLDRRLPYGPSDLLDYAPIAKSHVGEGMSLADACAAAIQWSDNTAANLVLATIGGP -AGVTDFARSLGDVVTRLDRNEPSLNSAIPGDPRDTTSPYAMARDLQALLLGDALSEASRK -QLEAWMVGNQTGGPRLRAGLPADWGIGDKTGSGDHGVANTIAILRPPGRAPLFVAVYYAE -SDRSMDDRNAVNRDVALVIA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A5C5A4S4_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. KBS0712 TaxID=2578111 RepID=A0A554S2M4_9BURK ---DAETQLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASLLGRRVSVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTSPAAMADTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A640LXU0_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY9_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A221SNH6_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=Q6REX6_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGASKRGARGIVALLGPNNKAERIVVIYLRD -TPANMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=4 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTE5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPMIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium sp. UNC302MFCol5.2 TaxID=1449065 RepID=UPI0012DD7A6D ---DLDAAFKGLDEKTGARLGVAALDTASDSKI-EYRAHERFAMCSTFKFLAAAAVLAKVD -RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP -KGLTQYARSLGDATFRLDRRETELNEAAPGDPRDTITPAHILKDLQKTVLGNALAKSSRD -QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD -PKGTADSRNEIHRKVASLVAE-- ->[subseq from] Beta-lactamase n=6 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9FD24_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0009F6C565 --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BGSC 6E1 TaxID=526970 RepID=C2NHX5_BACCE --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0005ABAC56 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000949A6B1 ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLGRAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTLPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF970DE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q6GWS8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSREPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERDRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Andreprevotia sp. IGB-42 TaxID=2497473 RepID=UPI00135C3D25 --------LAALEKQAGGRLGVCAIHTADGVQT-GYRVDERFPFCSTFKLMLASAVLARSV -HATGLLQQRIRYGKRDLVSYSPISEKHLGEGMTVAELCAATIQYSDNAAANLLIQLLGGP -AAVTRFARSIGNNTFRLDRRETALNTAIPGDARDTVTPAAMARSVQALALGNALPATQRE -QLQAWLRGNTTGGKRILAGVPAGWAVGDKTGTGAYGTTNDIGVIWPASGAPIVLAVYYTQ -HGADAKPKDEVIAEATRIVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI0003632B26 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CF122 TaxID=1144312 RepID=J3BR40_9RHIZ --dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRVVYDQDKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDSMVDTLGNLTLGSALSEPSRD -KLVEWMVANTTGGARLRAGLPDAWKIGDKTGTGNNGSAADIAIVWPPGHGAILVAAYVTQ -AKAPASEINPIFAEVGKIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CB01531 TaxID=1718947 RepID=A0A1Q5AT61_9ACTN -------DFARLEAEFDARLGVYAIDTGTGRTV-EHRADDRFGYASTFKALAAAAMLDAAS ---TAELNQVVRYARADLVTHSPITERHVGTGMTLRELGDAAVRYSDNTAANLLLKRLGGP -AGFERALRDLGDQVTDPERIETDLNEAAPGDRRDTSTPRALATDLRAYVLGDALSAEDRA -VLTGWLKGNTTGDKLIRAGVPAGWQVGDKTGSGGYGTRNDTAVIWPPDGAPIVLAVLSSR -DEQDAEYDDKLIAQAAKLTVE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D358B59 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQHLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNRQIAGIGAALIEHw ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000986911D ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRPIHYSQNDMVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLERWELELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SN1 TaxID=2055158 RepID=A0A2M8T1I8_9BACI ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEEALRQIGDKVTVADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKEWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. finitimus TaxID=29337 RepID=A0A243GK21_BACTF --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS ---TEKLNDVITYTKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP -KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SH7-1 TaxID=2217818 RepID=UPI0011CC72C1 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7AD333 ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 18065 TaxID=2681411 RepID=UPI0013586BE8 ---QFAQALEAIEARIQARLGAFVLDTETGMTL-GYRADERFPMCSTFKAIAAAAVLSRVD -AGREDLSRRLHWKKADLIAHSPVTEKHVKAGLTLAELCHAATTVSDNTAANLLLEAIGGP -AGFTAFVRSLGDPVTRIDRMEPALNSAKPGDKRDTTSPAAMAALLKALVLDDALSPTSRD -QLGQWMIANTTGGLKLRAGLPRGFTIGDRTGAGANGTNNVIAVIWPPERKPLVATVFITE -TKTPRPETDPAMAEIGRLLT--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FE02263 --dDVTERLRQLEERTGGRLGVAVLDTETDISF-GHRETERFAMCSTFKALAAACALARVD -RGKEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGLVLSQEGRK -RLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=UPI0007217C87 ---DLARQLARIEAQAGGRLGVAILDTASSKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEATITRSDNTAANLLLDSIGGP -AALTAFARSIGDRVTRLDRNEPTLNEATQGDPRDTTTPAAMLADLRALLLGEHLSAASRE -QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVVWPEGRAPVLVVAYLTG -ATATATQRDAAIAQVGALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTB7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AELTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=5 Tax=Bacillus anthracis TaxID=1392 RepID=A0A0F7RBX2_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=5 Tax=Bordetella TaxID=517 RepID=A0A5Q1KKV8_BORPP ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQSASRQ -RLADWLLASQTGDTRLRAGLPAGWRIGDKTGAGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis (strain Al Hakam) TaxID=412694 RepID=A0REB0_BACAH --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A380PPG3_YERFR ----LGNQLAELERNSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPGLLDKHIKYHESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ASVNAFARSIGDQVFRLDRLEPDLNTALPNDPRDTTTPAAMADSMNKLVLGDALPVAQRE -QLTLWLKGNTTGANTIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVLVIYFTQ -REKDAKPRRDVLAAATKIVLSH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAW0_9ENTR --dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQNIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=2 Tax=Kribbella sp. VKM Ac-2575 TaxID=2512212 RepID=A0A4R7TFP3_9ACTN --------FSALEKQYDARLGVYALDTGTGRTV-TYRADERFAYASTSKALSVGALLSDGR -----NLDKLIRYTEADLVTYSPITEKHVATGMTLRQICDAALRYSDNTAANLLFRELGGP -AGLQARLHRLGDRTTHVDRTEPTLNEATPGDIRDTTTPRAIATSLRAYTLGQALPIARRA -LLIDWMRRNTTGDTLIRAGVPKNWKVGDKTGSGGYGTRNDIAVVWPPGRSPIVLAIMSSR -ATADAKYDDALLAAATELVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. Root482 TaxID=1736543 RepID=A0A0T1X667_9RHIZ --kSIDERLAALEKRTGGRLGVSVLDKRTNISF-GCRMDERFAMCSTFKMLAGAFALARVD -KGEEDLDRRITYRKADLSPYSPVTEKHTGKKMAVAELCEAAITLSDNTAANLLLESFGGP -AGLTAWLRSIGDPVTRLDRNEPEMNRVKNGDPRDTTTPQAMLETLDRLVLGDVLKPASRE -QLIAWLVANKTGDERLRAGLPSGWTVGDKTGTSGKGELGDVAIIWPSKERPILVSVYIAD -GVGKTKTLNPVFAEIGRMVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sinorhizobium sp. M4_45 TaxID=2037901 RepID=A0A2N8K3N7_9RHIZ ---DVTERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGREVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -EGLTSWLRSIGDETTRLDRTEPELNEARKGDPRDTTTPAAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIAVAWPQGRGPILICVYMGE -AKAPLDDLNPVFADIGSIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. YR634 TaxID=1884385 RepID=UPI00089C7381 ---SAEAQLAALESASDGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERST -KDSGLLSRNISYSKADLVAYSPITEKHVATGMTVAAMCAATVQYSDNAAANLLLKVLGGP -PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD -QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASATRIAVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q9A141_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax caeni TaxID=343013 RepID=A0A1I7H289_9BURK ---SLLSALRGVEQDVGGRLGVAVLDTGTGRLA-AHRGGERFALCSTFKLLLAAQVLHRVD -QGVEHLAQRVAYGQADLLDYAPVTRQHAGGALTVAELCEAAMAWSDNTAANLLLARQGGP -QALTDWLRTLGDPATRLDRNEPALNDVPPGDVRDTTTPEAMARTLQAVALGEVLTPASRE -RLQGWMLGCRTGDQRLRAGMPPGWRIGEKTGTGPRGTSNDIGVLWPPGRAPVVLACYLTG -STADGARRDAALAAVGRSVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A0T9TEX9_YERFR -----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAASMNKLVLGDALPATQRE -QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ -REKDAKPRRDVLAAATKIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B7FDD7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPAIMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A168KQ64_KLEOX -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVARPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLVRHw ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella TaxID=517 RepID=UPI00052923F3 ---QAQRQLALLEQRHGARLGVQVQDRDSGGAF-SHRADERFPLCSTFKLLAAAAVLARAD -RGDDSLARLIRYGATDIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRVTRLDRIETALNEARPGDPRDTTTPAAMAGNLERLLLGDALQPASRQ -RLADWLLASRTGDTRLRAGLPSGWRIGDKTGAGGNGTNNDVGVIWPRDGAPVLITAYLTQ -SSASRETQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q846Q1_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETERNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum halopraeferens TaxID=34010 RepID=UPI000424AE35 -------ALADVERRLDARLGAAILDTQTGRRW-SHRADERFPMCSTFKALACAALLVRVD -AGREDLGQRVRFTAADLVTWSPVTRERAGGDMTLDELCVATMTQSDNTAANLILTRLGGP -SAVTDFARTLGDGVTRLDRMETDLNSAIPGDPRDTTTPAAMLANLQALVTGDALSGPSRE -RFTDWLVANRTGEARLRAGLPGGWRTGDRTGAGANGTNNVVAVIWPPGRAPVFATVYITR -TKATFETTNAAMADIGRALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00040FD53D ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMIVE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000B4153B3 ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIQHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar andalousiensis BGSC 4AW1 TaxID=527032 RepID=C3G367_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. JKLM13E TaxID=2582918 RepID=UPI0011064CA0 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005E1EFBF -----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ESVNAFARSIGDQAFRLDRLEPDLNSALPNDPRDTTTPAAMAASMNKLVLGDALPATQRE -QLTLWLKGNTTGAETIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ -REKDAKPRRDVLAAATKIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sophoriradicis TaxID=1535245 RepID=A0A2A5KNE4_9RHIZ ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KDDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEASCD -RLINWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000808B31E ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKEVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D6EAFCE --nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKATEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S6YTK7_9XANT ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGVTAFLRGIGDAHTRSDRREPEMNRFTPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus penneri TaxID=102862 RepID=A0A379EM03_9GAMM --nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKATEIVTKEf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sonorensis TaxID=119858 RepID=UPI000497895C ---ALNDAFAKLEDQFDARLGVYALDTGTNQTI-AYRADERFAYASTHKALAVGALLQQKS ---ITDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP -DGFKKSLGKIGDKVTNPERFEPELNEVKPGETHDTSTPKALATSLKAFTIGDALPKEKRM -MLIDWLKRNTTGDALIRAGVPKGWEVGDKTGAGSYGTRNDIAVIWPPKGDPIVLAILSSR -DQKDAEYDDKLIAQAAKEVID-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ3_KLEPN ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE3A284 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. PEPV16 TaxID=1820614 RepID=UPI00124CD752 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=2 Tax=Paraburkholderia ginsengisoli TaxID=311231 RepID=UPI0005A7DD79 --eAIRARLAQIEATSGGRLGVSIMDTTSGLRA-GLRGDERFPMCSTFKLLAAGAVLTRVD -RGQEDLQRRMVFSASDLVPNSPGTSRHTRELMSVAELCKAALTLSDNTAANLLLASFGGP -AAVTAFARSLGDGVTRLDRIEPELNEAIPGDPRDTTTPNAMLGNLRELVLGDHLSKGSRA -QLLAWLAANETGAARLRAKLPKDWGVGDKTGTGERGTANDIAILWPPGRGPVLVTVYLTE -TDGDATRSNAAIASVGALVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI000BE7B904 --dDIQHRIAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSIFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVTELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=C2VTY7_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPRDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Proteus penneri TaxID=102862 RepID=Q8VTN0_9GAMM --nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKATEIVTKEf ->[subseq from] Beta-lactamase (Fragment) n=179 Tax=root TaxID=1 RepID=J7K3B2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEI-------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00048098E2 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSENHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGNTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=A0A443VPZ4_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAERIVVIYLTG -TPATMDERNKQIAAIGATLVTHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C0L621_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWKTELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTH7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQISDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0009B90691 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SH5-2 TaxID=2217834 RepID=UPI0011EBB58D --qATYKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGILLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFRKIGGP -KGYERALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKGFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8P5B8_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D689980 --nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ -QEQDAKYRKDIIVKATEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. es.034 TaxID=1761763 RepID=A0A2A9BTR6_9BACI ------HKFMQLEKKFDARLGVYAIDTGTKRTV-VYRPDERFAYTSTYKALAAGAVLQQNS ---MDELDEVITYTKDDLVTYSPITEQHVDTGMTLRGICDAAIRYSDNTAGNLLFQELGGP -DGFENAMRQIGDPVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPEDKRT -ILTDWMKRNTTGDELIRAAVPKGWVVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAVLSSR -DTKDAAYDNELIAKAAKVTVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00143F7F37 ---NIERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAAFVLVRAD -KGEENLDRRVSYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=X5D266_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTEGKTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRXDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8VP67_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHFADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLSAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD4886 ---DLDAAFKGLEEKTGARLGVAALDTASDSKI-EYGAHERFAMCSTFKFLAAAAVLAKVD -RKEEKLDRVIKYGKGDLVAGSPATGKHVDEGMTLAALCEAAITLSDNTAGNLLLDNLGGP -KGLTQYARSLGDATFRLDRRETELNEAAPGDPRDTITPAHILKDLQKTVLGNALAKSSRD -QLIEWLLANKTGDKRLRGGLPKGWSVGDKTGTSDSGMANDIAVIWPPSRKPILLAVYLYD -PKGTADSRNEIHRKVASLVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=Q6HIK9_BACHK --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0C5C5N2_KLEPN ------EQIKLSESQLSGHVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain AH820) TaxID=405535 RepID=B7JPL5_BACC0 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A6B3JR28_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI000B65D898 ---SLDNQLAELEKSSNGRLGLALIYTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LEKEAEPRRDVLAAATKIVLAH- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0S3C5I0_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS ---TEKLNDVITYTKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP -KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Roseomonas sp. M0104 TaxID=2545983 RepID=UPI001369418E ---ELARTFARIEAAHGGRLGVAVLDTGSGRQA-GHRQDERFPMCSTFKLLAAGAVLARAD -AGQERLDRRVRYGKEELVTYSPVTEKHAGSEMTMAELCEAAITLSDNGAGNLMLDSLGGP -AGLTRWLRGLGDGVSRLDRRETELNEARPGDPRDTTTPAAMLADIRALTLGEALSGAARA -QLRAWLRGCRTGNATLRARLPQGWVVEDKTGSGANGTRNDAGLLCPPGGPPVLVAAYLTG -SPADGAARDAVLAEVGAAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus stackebrandtii TaxID=1123042 RepID=UPI001408FACC ---SLHQQLAELENSTKGRLGVTLINTANGQEL-QYRGNERFPFCSTFKLMLVAAVLHKSM -SQSELLAKHINYRESDLQSYAPIARKNLNQGMSITQLCAATLQYSDNTAANLLIKELGGL -AAVNHFAQGLGDKAFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVKKIVLGETLAEPQRE -QLVVWLKGNTTGNASIRAGAPTGWVVGDKTGSGDYGTRNDVAVLWPPEGSPVVLAIYFTQ -HQKDAESRNDVLASATRLVMEH- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2B6C3T5_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI000BE8FA39 ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLYTLGNLTLGSVLAEASSD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia madseniana TaxID=2599607 RepID=UPI0012B43530 ---AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAASFVLTRVD -HGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARCNAAIADVGALIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia aleksiciae TaxID=263819 RepID=UPI0005DF8DAE ---SLDNQLAELERTANGRLGVALINTANGSKV-QYRGGQRFPFCSTFKLMLTTAVLGQSQ -SLLGLLDKHIRYHESDLLSYAPITRKNLAQGMTVSQLCAATIQYSDNTAANLLIKELGGL -EAINQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASIHKLVLGEALKTPQRE -QLVVWLKGNTTGDATIRAGVPTDWIVGDKTGSGDYGTTNDVAVIWPSQGAPLVLVLYFTQ -RQKDAEPRRDVLASATKIVLSH- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. BAV 3049 TaxID=2654188 RepID=UPI00131E31FF ---DIQQKLADLEKDAGGRLGVALINTADNSQI-LFRGNERFPLCSTSKVMAASAILKQSE --TKNLMNHRVKIKKSDLVNYNPITEKYVGKEMTLGELSAAALQYSDNTAMNKLISHLGGT -DKVTRFARSIGDKTFRLDRTEPTLNTAIPADKRDTTTPLAMANSLHRLTLGKALGEAQRA -QLVEWMKGNTTGAQSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPPNHAPLILVTYFTQ -PVQDAKARRDVLASAAKIVT--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0004489267 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus mucilaginosus 3016 TaxID=1116391 RepID=H6NFE0_9BACL ---SAKQPFAQLESEYKARLGVYAVDTGTGRTI-EYRPDERFAYASTFKALACGAVLKAKP ---LEGLEDRVTYTSGELVTYSPVTEKHVSTGMTLRELCDAAIRYSDNTAGNLLLKQLGGP -KGFEAALKEAGDAVTKAERYETELNEAVPGDDRDTSTPRALASSLRAFTLGDALSADKRD -VLTDWLRRNTTGGELIRAAVPEGWVVGDKTGAGSYGTRNDIAVIWPPDGPPIVMAVLSSR -DTKDAAYDNALIAKAAKAALD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0004F56FDE ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus xerothermodurans TaxID=1977292 RepID=A0A2W1NRK9_9BACL ----TEQSFAQLEQQFAAHLGVFAIDTGTGRTV-AYQADKRFAYTSTFKALAAGAVLLNSS ---TEELDENITYSADDLVTYSPVTEKHVTTGMTLREICDAAVRYSDNTAGNLLLKRLGGP -AGFEAALRQIGDTVTQADRYEIDLNEAVPGDDRDTSTARALATSLQAFALSDVLPENERS -ILTDWLKRNTTGAELIRAGVPQGWTVGDKTGAGGYGTRNDIGIVWPPNGDPIVMAVLSSR -DTQDAAYDNALIAHATKVAVN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD6B17 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAXAIARNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 6 TaxID=463024 RepID=A0A261VWQ4_9BORD ---QAQRQLALLEQRHGARLGVQVQDRDSGGAF-SHRADERFPLCSTFKLLAAAAVLARAD -RGDDSLARLIRYGATDIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRVTRLDRIETALNEARPGDPRDTTTPAAMAGNLERLLLGDALQPASRQ -RLADWLLASRTGDTRLRAGLPSGWRIGDKTGAGGHGTNNDVGVIWPRDGAPVLITAYLTQ -SSASRETQNAVLAEVGRIAAH-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI00081CF7A4 ---QAQRQLALLEQRHGARLGVQVQDRDSGGAF-SHRADERFPLCSTFKLLAAAAVLARAD -RGDDSLARLIRYGATDIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRVTRLDRIETALNEARPGDPRDTTTPAAMAGNLERLLLGDALQPASRQ -RLADWLLASRTGDTRLRAGLPSGWRIGDKTGAGGHGTNNDVGVIWPRDGAPVLITAYLTQ -SSASRETQNAVLAEVGRIAAH-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102FF756 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I612_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCAA0 --dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLMAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYLTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum huttiense TaxID=863372 RepID=UPI0003F7ADF7 ------SRLAKLEAGVAGRLGVEILDSGSGRRW-GYRADRRFPMCSTFKFLAASAVLRRVD -TGAEQLDRRIVYGEDVLVNYSPTTGKHTGGDLSLAQLCEAAITLSDNTAANLMLESMDGP -AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE -NAATDARRDAVHAEVGRLI---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus dielmoensis TaxID=1347369 RepID=UPI000945271E ---QLNREFANLESQFDARLGVYAIDTGTNRTV-SYRPNERFAYASTYKALAAGALLQQSS ---MDQLDELVTYNSEDIVSYSPVTELHVDTGMTLREVIDAAVRYSDNTAGNLLLKKLGGP -EGFEAALRQIGDHTTMADRYETELNAAIPGDKRDTSTPKALAASLEAFAVDDVLPAGKRA -LLTDWMQGNATGDALIRAGAPTDWEVADKSGAGSYGTRNDIAVVWPPNRAPIVIAVLSSR -DTQNAAYDNALIAEAAKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia rubidaea TaxID=61652 RepID=A0A3S4WU26_SERRU --pATLDTIKDAESRLHGRVGYAELDLASGKMMdSYRADERFPMMSTFKVSLCAAVLARVD -AGQEQLERRIRYRQNDLVEYSPVTEKHLAEGMNVGELCHAAITMSDNTAANLLLSTLGGP -SGLTAFLRKTGDSVSRLDRWETALNEALPGDERDTTTPESMARTLHNLLTGDALSAESRR -QLMRWMEMDNVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG -TKATMDERNKQIADIGAALINHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A1J9WHJ1_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIVRNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A154IJB8_RHILE ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVSWPPDRGPIVAAVYISE -TTVSAKELNPVFAEVGRMIVE-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0012B8E727 ---AIQQKLANLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRADLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia agricolaris TaxID=2152888 RepID=UPI001292B7F4 --eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLAAGLVLTRVD -HGQENLERRVVFSKSDLVPYSPATSRHTRELMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGVTRLDRNEPALNEATPGDPRDTTTPNAMLGNLRELLLDERLSSPSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE -TSGDAARCNAAIANVGAVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0005DC6285 ----LGNQLAELERNSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPGLLDKHIKYHESDLLSYAPITRKNLAHGMTVSQLCAATMQYSDNTAANLLIKELGGV -ASVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMADSMNKLVLGDALPAAQRE -QLALWLKGNTTGANTIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVLVIYFTQ -REKDAKPRRDVLAAATKIVLSH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDAD570 --kDIDKQLASLEKRTGGRLGVCVLDTKSNASF-GHRQDERFAMCSTFKALAAAFVLARVD -KGEEKLGRRIAIAKADLHSHSPVAEKHVGDTMTVGELCDAAVTYSDNAAANLLLASFGGP -DGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMIRTLGKLLLEDVLSPSSRD -QFTAWLVANRTGGRRLRAGLPAGWTIGEKTGTSGHGEVGDVGFMRPRDGHTILASVYIAE -ATKPMKELEPIFAEVGKLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus camelliae TaxID=1707093 RepID=A0A2N3LLX8_9BACI ---AINQKFVHLEKKFDARLGVYAIDTGTKRTI-AYRSDERFAYASTYKVLAAGVVLQQNS ---IDRLDEVIHYSKDDLVSYSPITEQHVDTGMTLKEICDAAIRYSDNTAGNLLLEKLGGP -KGFEKSLREIGDTITRSDRFETELNEATPGDLRDTSTPKALAKSLKAFTVTNVLPSDKRR -ILTDWMRGNTTGDKLIRAGAPKGWAVGDKSGAGSYGTRNDIAIVWPPHKKPIIIAILSSH -KTKDATYNDELIENAAKVALNAf ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q1WBU2_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAAL---- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) TaxID=396598 RepID=B1FU45_PARG4 ---AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -RGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV -QLLAWLAANETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG -TAGDAARNNAAIANVGALVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CCGE 510 TaxID=1132836 RepID=J6DX46_9RHIZ --dNIQRRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARAD -KGEESLDRRVTYGKEKLVDYSPLSEKHAGTDMTIAELCAAAVTVSDNTAGNLLLESFGGP -AALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASSD -RLIAWLVASTTGGERLRAGLPKDWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLATIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. b13 TaxID=1761774 RepID=A0A1R3VNU1_9BURK ------EALAVLEARMGGRLGVCAIDTGSGARL-VHRAEERFPFCSTFKAVLAAAVLARSG -DTPDWLSQRVRYGSADVVSYSPISGQHVGAGMRIDEMCAATLQYSDNTAANQLMKVLGGI -DAVTAFARSVGDATFRLDRWEPELNTAIPGDVRDTSTPAAMADTLRAVMLGNVLRPWQQQ -RLQQWMLGNRTGDKRIRAGVAAQWRVADKTGTGEYGTTNDIGVLWPPERAPIVLSIYFTQ -PQQDAPARDEAIEQATRIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. IMH TaxID=1267600 RepID=UPI00046ABEC5 -hqATLDKVREAEHLLKARVGYAELDLTSGQLLeSYQADARFPVMSTFKVLLCGAVLARVD -AGQEQLDRRIKYRESDLITYSPVTEKHLAEGMTVSELCSAAITMSDNTAANLLLSTLGGP -QALTAFLRKIGDPVTRLDRWEPALNQALPGDERDTSTPEAMAKTLRQLLTGEVLSVSSRQ -QLMEWMVADKVAGPLIRSVLPEGWFIADKTGAGERGSRGIVAALGPDGKASRLVVIYLTE -SQATMDERNKQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A0B4R7I2_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEP--NTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLILVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia graminis TaxID=60548 RepID=UPI000DEF0CA9 ---AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -RGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV -QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG -TAGDAARNNAAIANVGALVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=UPI00037BF958 ---SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST -RDSSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI0002900D41 ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -QLADWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009769CC1 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8TG68_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLSPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAAL---- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTG2_KLEPN ------EQIKLSESQLSGRVGMIEMDPASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATFGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. G2661 TaxID=2698874 RepID=UPI001379070E --nTIEAQLSELEKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKHRKDIIAKATEIVTKEf ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=UPI0007CC3D0D ---AIHQKLTALEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEP--NTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKNRKEVLAAAAKIVTE-- ->[subseq from] TEM-1 beta-lactamase n=1 Tax=Methylobacterium sp. TaxID=409 RepID=A0A389MUP9_9RHIZ ---ALARRLGEIERASGGRLGVAMRDTGTGLTV-GHRADECFPLCSTFKLLAAGAALARVD -AGRESLERRVPYTAADLVDYSPVTKARVGEGMALGALCEAALTLSDNTAGNLILASLGGP -AGLNAWLRGLGDPVTRLDRIEPDLNEARPGDARDTTTPAAMLADLDRLALGTALTSASRG -TLVAWLRANRTGGARLRAGLPPAWQVGDKTGSGDRGTTNDVGLLWPPGGAPILVAAYLTE -TDAPQERRNASLAEVGRAVASH- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243BM28_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPEDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B59601 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYQPNERFAFASTYKALAAGVLLQQNS ---TEKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNKLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009753A7D --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B5992A --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. R339 TaxID=1764273 RepID=UPI000B5306D9 ---NVERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLERRVSYGKEKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSCS -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPAKDLNPIFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000406C23A ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRSEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii TaxID=386 RepID=A0A1B8RE65_RHILT ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRSEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q5DUJ5_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFALSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=A0A2Z5MLW6_9BURK ---TIRARLREIEAHSGGRLGVAIVDTTSGLHA-GVHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE -TAGDAARCNAAIASVGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C03 TaxID=1945858 RepID=A0A1V3Q011_9GAMM ----AQARLAALERQHGGRLGVAILDTGNGRRI-GHRADERFLMCSTFKLLAVAAVLARVD -REAERLDRRIVFDQEAVLAYAPVTSHRVGAPMTVAELCQAAITVSDNTAANLLLTSLGGP -TAVTAYVRSLGDGVTRLDRIEPELNVASPGDLRDTTTPSAMLADLSTLLLGDALSAASRE -QLAAWLRATSTGTEQLRAGMPAGWRVGDKTGSGAQRETNDIAIIWPPQRKPLLVTAYYAG -SAASNDERHAVLAEVGRIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q83W48_PSEAI ---ETLVKVKDAEDKLGVRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASKRGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] Beta-lactamase KPC-8 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B6V684_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas bohemica TaxID=2044872 RepID=UPI000DA61DEC ----IKQKLAELELRHGGRLGVAILDTASQRLI-DHRGNERFALCSTFKALAVAHVLARVD -RKEEDLSRMIVYGQEQLVTYSPITEKHTGEGLSVGSICEAAITLSDNTAANLLLDSFGGP -ESLTDWLRSTGDEVTHLDHREPKLNENRPGDPRDTTTPVAMLHSLRRLALGDALSDASRD -QLIAWLVSNKTGDQKLRAGLPKGWRVGDKTGSGSNNAGNDVAVIWPPNRPPLIVTVYYTD -SKASSEQINGVMAEIGKWVA--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001261AD9B ------EQIKLSESQLSGRVGMIEMDLASGRTLtTWRADERFPIMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B8YHZ7_KLEPN ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATIAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3M0DDG8_KLEPN ------EQVTRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLLRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A328WCW7_PAELA ---------------DGIELYVGVQDLSGGGKI-QAGSSNVYYAASTIKMAIVTALMQDIE -AGKYALEQTVQVKPEQVVGGAGSLKDKFPQEITIERLAGLMITQSDNTATNALIDLL-GF -ERINAFIDEQGFKTMQLGRKMMTPAKS--PAADNYVNGEELLTLLERIYTGEIVSAQSRD -QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-VAVTVLTKV -NKKAQELGNPVVQRAAKAVYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A328WCW7_PAELA ------------AEEKGIRVSVGLKDLSDDREL-LLGSRQSYMPASTIKMALVSALMKEVD -AGRLTLEQKVKVEQEDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL -NKVQALLDELGLDVMHLGRKMFAAA--PTPEQDNYINAEDLVHLLANIHSGEFLSENSRD -QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLQPGR-EIAISVLTEV -TTEAQAIGNPVVQEIAKAVYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q7X5A6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -HLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus glycinifermentans TaxID=1664069 RepID=A0A0T6BTP5_9BACI -----SNQFSRLEDQYDARLGVFALDTGTNKTV-TYRADERFAYASTHKALAVGALLKQTS ---IADLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP -SGFKQSLREIGDNVTNPERIEPDLNEVKPGETHDTSTPKALAKSLQAFTVGDALPKEKRE -MLVDWLKRNTTGDALIRVGVPKGWEVADKTGAGSYGTRNDIAVIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEAAKEVIK-- ->[subseq from] Beta-lactamase n=2 Tax=Methylobacterium haplocladii TaxID=1176176 RepID=A0A512IMI4_9RHIZ ---SAEEAFARIEAAVGGRLGVATLDTGSGRRL-SYRAEARFPLCSTFKLLAAAAILAQVD -KRREQLDRRVPYTTADLVDYSPTTKIRAAEGMPLADICEAAITLSDNTAGNLMLAQIGGP -AGLTAFLRAGDDAVTRLDRIEPDLNEALPDDPRDTTSPRAMVSDLERLVVGDALSAGSRG -QLTAWLLANQTGGTRLRAGMPRDWRVGDKTGTGDRGTANDVGILLPPGGAPILAAVYLTE -STGSAEQRNAAIADTARTIVR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces kanamyceticus TaxID=1967 RepID=A0A5J6GAM9_STRKN ---DVRRRLRELEKGYPGRIGVHALHTGTGATV-AYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDVLIRYGRDDLVEYSPRTEMHLETGMTVRELCDATLTYSDNSAANLLMRRIGGP -TGITEFARSIGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTENLRRLVLGDALHPLDRD -QLIRWLLENTTGDKRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKRAPLVVSVYTTR -LDPDTPGEDRIAEDITRIVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG6_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKB5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH2_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CC9620 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFLMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=bacterium M00.F.Ca.ET.191.01.1.1 TaxID=2563911 RepID=A0A4S0JKF0_9BACT ---AIRARLAEIEAQSGGRLGVSIVDTTSGLHA-GLRADERFPMCSTFKLLAAGAVLARVD -RGEENLQRRIVYSQSELVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRALVMGEQLSSTSRV -QLLAWLAANETGGARIRARLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILLAVYLTG -TAGNAARSNAAIADVGALVVE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2B82CA ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGH -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q6W9D3_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLIRHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI0005F7C708 -hdATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLLSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNRQIAGIGETLVKHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q6W7F2_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLVTHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8EQ15_BACCE ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGEVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWKVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=A3FFR5_CITFR ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARLQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=H9AXM1_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSRNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDCWEPELNEAIPHDERDTTMPAAVATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A444P8M7_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALASAFVLARAD -KGEENLDRRVSYSKEKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -KLIAWLVESTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora mirobrigensis TaxID=262898 RepID=A0A1C4YY61_9ACTN -----DNEFRQLEEKFDARLGVYAIDTGTGRTV-RYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITEQHVDDGMTLRAIADAAVRYSDNTAGNLMLRRLGGP -QKFEKELREIGDKVTDPARWETALNEARPGDRRDTSTPRAMAGSLRAYAVGNALEPADRA -VLNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDADYDNVLIAEATKVVLAGw ->[subseq from] Beta-lactamase SHV-4 n=2 Tax=Enterobacteriaceae TaxID=543 RepID=BLA4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQL -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q4L202_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -PPATMDERNKQIAAIGATLVTHw ->[subseq from] class A beta-lactamase n=1 Tax=Proteus TaxID=583 RepID=UPI000D69BD2C --nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTIGMTLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVIYFTQ -QEQDAKYRKDIIAKAAEIVTK-- ->[subseq from] SHV family class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BDEEFE1 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAPVGGP -AGLTAFLRQIGDTVPRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. JPY366 TaxID=668820 RepID=UPI00048EC465 ---AIRARLEDIQAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -RGEEDLQRRIVYSKSELVPYSPATSKHTRELMSVAQLCKAAITLSDNTAANLLLQTFGGP -AGLTAFVRSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLSSASRA -QLLAWLAANETGGARIRAKLPKNWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTE -TAGDAARGNAALANVGALVVE-- ->[subseq from] Beta-lactamase n=8 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q939H4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase SHV-3 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQL -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=A0A1P8JQI2_9BURK ---RFRQRMQAIEQASGGRLGVAVRDTHSGAAF-AHRGGERFPLCSTFKFLAAAQVLARVD -SGAEQLDRRIAVLASDLVPYAPVTQPRVGGEMTVAELCDAAVTLSDNVAGNLLLRSFGGP -AALTAYLRGLGDGQTRLDRIEPELNQALPGDPRDTTTPEAMLQTLHRIVLGDALSPPSRA -QITRWLVDNKTGDRKIRAALPAGWRVGDKTGAGAFGTNNDIAVLWPPGRLPVLVTAYLTD -TSADQAVRDQALAEVGRLVV--- ->[subseq from] Beta-lactamase n=2 Tax=Citrobacter TaxID=544 RepID=A0A4P7Q172_CITFR --pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSQRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE -SQATMEERNRQIAGIGATLIQHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B0FP98_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGENVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTNQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A164DHN1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis nigrescens TaxID=381445 RepID=UPI000369B36A ----IYRELRALEQRHSARLGVYAVNTKTGATV-AYRAQERFPLCSTFKTLAAAAVLRDLD -RDGEFLDKVIRYTEKDLVNGSPITKDHVGEGMRVGDLCAAAICYSDNTAGNLLLRQLGGP -GGVTGFCRSIGDHRTRLDRWEPELNTAIPGDPRDTTTPGAIGRDYGRLVLGDALDPGDRA -RLTGWLKANTTSGKRFGAGLPDDWELGDKTGSGDYGTTNDVGVAWTADGTPIVLAVLSTK -HTQDAAYDDLLIADTARL----- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RGY2_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q2VCD9_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGSVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLIRHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A090YAH1_BACMY ---ATHREFAQLEKKFNARLGVYAIDTGTNQAV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLDEVITYTKDDLVEYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPTDKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DKEDATYDNELIAQAAKVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Y6AX36_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium BLR1 TaxID=506512 RepID=B5L5U5_9BACT --qDASAQLAALEAASGSRLGVVGFNTATGARV-QHRAEERFPFCSTFKLMLAAAVLERSA -KEGDLLARRVNYSKGDLVSYSPITEKNVATGMTVAELCAATVQYSDNGAANLLMKILGGP -SAVTAFARASGDEVFRLDRWETELNTAIPGDLRDTTTPAAMAASVQRLVLGNALGAAQRE -QLKTWLLGNTTSTQRFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVLAVYLTF -PQKEAKGRSDVVASATRIAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=A0A2V4KK02_9PSED ----LRQAMQQLEAASGSSIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRSV -SEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGMTLQRLLLTDGLPAAAQQ -QLQAWLKGNTTGDTRIRAGVPKDWVVGDKTGSGDYGVANDVAVIWPKDRAPWILVVFSRG -TKQDAPWNSETIAAATRIVVEAw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella TaxID=160674 RepID=UPI00062BE110 -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGSVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLVTHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A142K3H5_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIAEKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. 250J TaxID=1478142 RepID=A0A0L6FU89_9PSED --nSLRQAMQQLEAASGSSIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -VEPGLLARRIAYGTEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGMTLQRLLLTDGLPAAAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRS -TKQDAPWNSETIAAATRVVVEAw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014411CFB ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000D745CF0 ------EQITRSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -LLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. BK151 TaxID=2512132 RepID=A0A4R1ZKR6_9BURK ---SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST -RDGSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Competibacteraceae bacterium TaxID=2053538 RepID=A0A433I2A2_9GAMM -----QEQLAQLEKTAGGRLGVCAIDMSHGAQI-SHRGDERFPLCSTFKVILVAAILTRSS -RVDGLMQRRVYYKRSDLAAYSPMTERHIVDGMTVADLCAAALQYSDNTAANILIGIVGGP -AAVTEYARSIGNAEFRLDRWETDLNSSTPGDLRDTATPASMARSLQALSCGDALPPAQTQ -QLNEWLRGNTTGAKRIRAAVPADWSVGDKTGSGDYGVTNDIAVLWPPQRQPIVVALYYTQ -DEPKAPWRDEVIAAAARIVVDGf ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. BK370 TaxID=2512126 RepID=UPI0010526D06 ---SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST -RDGSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZC1_KLEPN ------EQIKLSESQLSGSVGMVEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413) TaxID=219305 RepID=C4RM91_MICS3 ------AELAALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTFKALAAGALLAATS ---DAELDRVVRYERADLVPHSPVTEQHVAGGMTLRAVADAAVRYSDNTAANLMLAELGGP -AGFERALRGIGDTVTDPARTETSLNEAAPGDVRDTSTPRAMATSLRAYALGDALSAADRT -VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDGAPIVLAVMSRR -AAKDAQPDDALIAEAARVTVD-- ->[subseq from] Beta-lactamase KPC-6 n=4 Tax=Enterobacterales TaxID=91347 RepID=B2CYF2_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A640J386_9BURK ---DAETKLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012EA6ADA ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGT -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRNLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=UPI0011A34345 -----GNQLAELERKSNGRLGVTMINTANGRKI-QYRGTQRFPFCSTFKFMLAAAVLGKSQ -TQPDLLNKHIKYRESDLLSYAPITRKNLAHGMTVSQLCTATMQYSDNTAANLLIKELGGV -ESVNAFARSIGDQAFRLDRLEPDLNTALPNDPRDTTTPAAMAGSMNKLVLGDALPAAQRE -QLTLWLKGNTTGAEAIQAGAPADWIVGDKTGSGDYGTTNDIAVLWPTQGAPIVMVVYFTQ -RENDAKPRRDVLAAATKIVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=UPI0014418288 ---NIEHRLATLEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGADMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q2VCE4_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLITHw ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2S1R3D7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEHLGRRIHYSQNDLVESPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEANRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I622_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H9CTU8_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B432296 ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000CEDB9BB ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A1E7U0B5_9BURK ---DAETQLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASMLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=UPI000F49C8C2 -heATVNQVKAAERQLEARVGYAELDLASGRLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNAAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPLAMAKTLHNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMDERNRQIAEIGETLVKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=UPI0013BCB733 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENLDRPVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. MWU13-2610 TaxID=2077146 RepID=A0A2K4MR30_9NEIS -----EQKIARLERDFGGQIGVYALDTGSGATV-SYRADERFPLCSSFKGFLAASALAHSQ -SKPGFLDQTLHYGKEDLIVWSPISEKHQASGMTVAGLCAATVQYSDNAAANVLMKQLDGP -AGLTAFMRSIGDSTFRLERWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAPQRQ -QLVDWLKGNTTGNQRIRAAVPAGWSVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA -SKKDIKHSDAVIADAAKAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A250DIU2_9BURK ----AETQLAELERACGGRLGVSGLHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -SAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] Beta-lactamase n=9 Tax=Enterobacterales TaxID=91347 RepID=A0A0G3QXS5_KLEOX ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia bonniea TaxID=2152891 RepID=UPI001290B981 ----ALTQLQELERSSGGRLGVLALDLTGHVPL-SYRADERFPLCSTFKTMLAAAILQRSR -SAPSLLAQQVQYRSGELASYSPVTRQHVEDGMSVGALCAAALQYSDNTAANLLLKILGGP -AAVTAFARSLGDNLFRLDRWEPELNSATPGDPRDTSTPAAMAHSLQRLLLGDALGAAQRT -QLRDWMQANTTGAARIHAGVPPTWQVADKTGTGDYGTTGDIAVLWPPGMPPVTLALYFTQ -PGKDAKARDDVLAAATRVLVS-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. JKLM12A2 TaxID=2583231 RepID=A0A5R9P7D0_9RHIZ ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTGMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPAHWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK376 TaxID=2512149 RepID=A0A4R3G5Z3_9RHIZ ---DADKQLAELEKKTGGRLGVAVLDTETNISL-GYRENERFFMCSTYKALAAGFVLARVD -KGEEKLDRRVMFGKDALVSYSPVTEKHAGTDMTVAELCEAAITMSDNTAGNLLLDSFGGP -SALTAWLRATGDDETRLDRREPDLNEAKKGDLQDTTTPDSMLDTIGLLTLGDTLSEASRN -HLIDWMVADKVGDARLRAGVPKDWKIGDKTGTGNNGALGDIAVIWPPDRGPFIVAVYIAE -ATAPMKDLNDVFAAVGKLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. N122 TaxID=1764272 RepID=UPI000B5A85A4 ---NIEKRLAALEKRTGGRLGVSVLDTQTSISF-NYRGDEAFPMCSTFKALAAGFALARAD -KGEESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPAKELNPVFAELGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I7ABU5_ECOLX ---DVQQKLAELERQSEGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAE----------------- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. OV446 TaxID=2135496 RepID=A0A2V3RBQ2_9BURK ---TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIMWPPSRGPILVAVYLTE -TADDAARRNASIADVGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A2S1LUS9_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMEDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5B3HZY6_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar guiyangiensis TaxID=180871 RepID=A0A242XUQ6_BACTU --qATYKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVINYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKEFTVGNALPDHKRN -ILTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKDAPYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Stappia sp. BW2 TaxID=2592622 RepID=A0A5D0W7B5_9RHOB ----LDKTVADAENRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGDLQPEHRVKIRKEDLVTYSPVTEKKIGSGMTYLELCDAAITISDNAAANLVLEAVGGP -QGLTEYLRSIGDTITRLDRAEPTLNEGQPGDDRDTTTPAAAVATLQKLVLGDALSPTART -RLTDWLLDNQVGKATLRAGLPEEWPVADKTGAGGNGSRNNIGVIWPDDRKPVVIAVYITQ -TAASFDDRNRAIADIAAALAD-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Yersinia TaxID=629 RepID=UPI00067091B8 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. OK233 TaxID=1882795 RepID=A0A2C9BXP5_9BURK ---AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD -HGQEDLERRIVFSKSDLVPYSPATSQHIRERMSVADLCKAAITLSDNTAANLLLLSFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARCNAAIANVGALVVA-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000FA45589 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELL-LASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. J15 TaxID=2035450 RepID=A0A2A6JQB8_9RHIZ ---NVERRLAALEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVSYGKEKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSCN -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPAKDLNPIFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. N4311 TaxID=1703972 RepID=A0A235ATA3_9RHIZ ---NIEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGDEAFPMCSTFKALAAGFALARAD -KGDESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPAKDLNPVFAEVGRMIVE-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0A1C3V8_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPGSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZR2_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVVLLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. BH2 TaxID=2528958 RepID=A0A4Y7QSG0_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTKQTV-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia bryophila TaxID=420952 RepID=A0A329CL71_9BURK ---TIRRRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLVAGAVLTRVD -RGQESLERRIVFSQRDLVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARDLGDGITRLDRIEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSSSSRA -QLLAWLVANETGGARLRAKLPRDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVVVYLTG -TNGDAARCNAAIAEVGALVVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 17Sr1-39 TaxID=2583531 RepID=A0A5C4LEG6_9RHIZ ---DAAARLAQLERRDGGRLGVEIRDTATGRRF-GHRADERFPLCSTFKAIAAAAVLARAD -KGQDDLNRRMTYGRDALLSYAPVTSKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP -AGITDFARAHGDTVTRLDRTEPTLNTALPGDPRDTTSPAAMVGLLDHVLLGRALSGESRA -RLLGWMQESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEIGRLIARSf ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. T31 TaxID=2054594 RepID=UPI000C292501 --eATVAMVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLTGRVLSPASQQ -QLLHWMVEDKVAGSLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG -TPASMDERNKQIAAIGKTLVAHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBC2DC ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0P0IGT7_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase LEN-30 n=1 Tax=Klebsiella TaxID=570 RepID=UPI0009BB5352 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D613_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-23 n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2Z4BW68_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. NEAU-SY24 TaxID=2292265 RepID=UPI000E23377C ---AIEAELASIEQGVGARLGVAIHDLETGLRT-GRRCSERFPMCSTFKLMLAASVLARVD -RRQEELERRIVFGADRIEQYAPVTRQHVGAPMSVAELCDAAVTMSDNTAANVLLDTIGGP -PGFTAFMRGLGDTVTRLDRTEPTVNTATPGDPRDTTTPVAMLGSLRKVLLGDALSPAARA -QLLAWGAGNRVGDARLRAGVPRDWRVADKTGTGERGTTNDIGILWPQDRAPILVTVYLTE -TDAPDRAREAAIADVARTVARH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A384WDR9_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQRERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia dilworthii TaxID=948106 RepID=UPI00040F9DB2 ---AIRARLKQIEAESGGRLGVSIVDTASGLHA-GLHADERFPMCSTFKVLAAAAILARVD -RREEDLQRRIVYSQSELVSNSPATSKHTRERMSVAELCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVLGERLASSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTG -TAGNAARCNAAIANVGALVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1F8026 ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGQLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGVTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP13_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=unclassified Klebsiella TaxID=2608929 RepID=UPI000C2993E0 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP11_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2DBB64 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTIPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=Q8L2F9_SALTM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAELSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTSELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERSRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. L1A1 TaxID=2502246 RepID=UPI0010F6A2AF ---SFEDALAEIEVRSGGRLGVAVLDTGSGELT-GRRIDERFPLCSTFKALAAAAVLARVD -AQEERLDRRVVFGREALVPYSPVTEPRIGGSMSLAELCEAAVIRSDNTAGNLLLQAIGGP -AGLTAQLRAFGDDVTRLDRTEPTLNEALPGDPRDTTSPGAMARTLAGLTLGSALTQPSRD -RLTAWLLDNRTGGKRLRAGLPSGWRIGEKTGTGEYGTTNDVGVIWPPEGAAQVVAVYLTA -TDRPLSEREDAIAAVARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. G2669 TaxID=2698881 RepID=UPI001412B6B3 ---TIEEQLTILEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE -KQAGLLNNYITIKKADLVPYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQNAKYRKDIIVKATEIVTKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A142YTR5_9BURK ---DLARQLARIEAQAGGRLGVAILDTAGTKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEAAITRSDNTAANLLLDSIGGP -AALTAFARSIGDRVTRLDRNEPSLNEATQGDPRDTTTPAAMLADLRALLLGEHLSSASRE -QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVVWPEGRAPILVVAYLTG -ATATATQRDAAIAQVGALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A286S471_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVDLLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase SHV-24 n=1 Tax=Escherichia coli TaxID=562 RepID=BLA24_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARGTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I6M7_KLEPN ------EQIKLSESQPSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3F057_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011EAFCE8 ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A3R9EF50_BACSP --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0011A3E0F9 ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPLDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LKKEAEPRRDVLAAATKIVLAH- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000F8CBD76 ----LRAQWAEIERRSGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] UPI001156C740 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001156C740 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] OXY family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI00025002AB ---AIHQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKYLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodospirillales bacterium 39-66-50 TaxID=1970570 RepID=A0A259MSY3_9PROT -----VSSLRELERRNGGRLGVAMFDTASGRRV-AYRGDERFPMCSTFKFLAAALMLARVD -RGEESLDRRIVFAASDLVTYSPATREHGGPAMTVDAICAAAVTLSDNTAGNLMLASFGGP -AGLTAFARVLGDTVTRLDRIETALNEGTPGDPRDTTSPLAMLATMQKLVAGDVLSSASRE -RLIGWLVANKTGDKRLRAGVPAAWRIGDKTGTGGNGSANDIAVAWPPGRAPVFVTAYYTG -STISDEARSAVIAEAGRIAT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDSKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CF394 TaxID=1500304 RepID=UPI00055BFDA3 --dEINRRMEALEKEIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEPDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWVRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVEWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPLSEINPVFAQVGKIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010396F36 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWVRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC-7 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B3GS81_KLEPN -----AEPFAKLEQDFGGSIGVYAIDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI001297FD9F ---DVTERLRQLEERTGGRLGVAVLDMETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLERRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG -QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE -AKAPVSDLNPVFAEIGKIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8J3I6_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Stella humosa TaxID=94 RepID=A0A3N1L1Y6_9PROT ---ATQARLIELEARHGGRLGVSVLDTGSGQRT-EHRANERFAMCSTFKLLAAAMVLERVD -RNEERLDRRILFGSSDVVDYSPATGPRAGGEMTMGEVCEAAMTLSDNTAGNLMLNSFGGP -AAVTTYARGLGDTVTRLDRMETALNEAATGDPRDTTSPAAMVDNLARLTLGPALSEPSRA -QLITWMVANRTGDRRLRAGFPDGWRVGDKTGTGGNGTAADIGVVWRPDRSPLVIAVYCAE -VTASAERRNALFEQVARVI---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. WSM2232 TaxID=944436 RepID=UPI0003FB9919 ---AIRARLTEIEAQSGGRLGVSIIDTTSGLHA-GLRADERFPMCSTFKLLAAGAVLARVD -RGEENLQRRIVYSQSELVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLQTFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVMGEQLTSASRV -QLLAWLAANETGGARIRARLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTG -TAGNAARSNAAIADVGALVVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4455E3 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIILAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSHIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B51831 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWGVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVVNAf ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii TaxID=386 RepID=A0A3E1BR83_RHILT ---NIEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGDEAFPMCSTFKAPAAGFALARAD -KGDESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2V5_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=6 Tax=Enterobacteriaceae TaxID=543 RepID=Q46759_ECOLX ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus dendritiformis TaxID=130049 RepID=H3SDM0_9BACL ---AAHREFAQLEKKFDARLGVYAIDTGTNQTV-AYRPNERFAYASTYKALAAGALLQQNS ---NDQLDEVITYTKDDLVEYSPVTEKHVAAGMTLGEIAEAAVRYSDNTAGNLLFKELDGP -KGFEKALRQIGDRVTQADRFETELNEAIPGDIRDTSTAKALATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRGGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNSAPIIIAILSSR -DKKDATYNNELIAQAAKVTMNAf ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. BIGb0149 TaxID=2485116 RepID=UPI0010607399 -hdATVNQVKAAERQLKARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVDYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -KGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMKERNRQIAGIGETLVKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=A0A1J9YMX5_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00069477F9 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kirstenboschensis TaxID=1245436 RepID=UPI000A88DFF2 ----IRARLQEIEADSGGRLGVSIVDTASGLHA-GLHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVSNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRNEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTG -TAGDAARCNATIADVGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter gillenii TaxID=67828 RepID=A0A3E2KSF3_9ENTR --pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSQRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITE -SQATMEERNRQIAGIGATLIQHw ->[subseq from] Beta-lactamase n=1 Tax=Roseiarcus fermentans TaxID=1473586 RepID=A0A366FRM0_9RHIZ ---AAADRLAALERSAGGRLGVAVLDTSSGETL-LRRADERFPMCSTFKLIAAAAVLKRVD -AGQETLTRFVPYRQADLLGYAPVTKAQVDAGMTLADLCAAAIDWSDNTAANLILDAIGGP -AGFTAFARLLGDSVTRLDRNEPTLNTAIPGDPRDTTTPLAMARDLQAVLLGDVLSEESRR -RLEAWLIADRVGDKRLRAGLPPDWGIGDKTGSGDHGTANTIAILRPPNRAPLLAAVYYTE -GPDSMDARNAVNRQVGEIVAATf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI00034A6AC3 ---EAQAALKALDEGFDGRLGVFALDTGSGATL-GQRAGERFPMCSSFKAVLAASMLDRSR -RQPDWLSHRVRYAKADLVSYSPVTERHVGEGMTVAELCAATVQYSDNGAANLLMAQSGGP -QALTAFARSHGDDSFRLDRIEPALNSAIPGDERDTTTPEAMARLLQRLVVAEGLPPRERQ -QLADWLRGNTTGARRIRAGVPAAWTVGDKTGTGAHGSASDIGVVWRPGMAPLALAIYTTR -PKADAPADEAVIAEAARIVA--- ->[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0ZX80_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI000F70A6F3 -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGSLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium crusticola TaxID=1697972 RepID=UPI000FFCA952 ---DAAARLAQLERRDGGRLGVEVRDTGTGRRF-GHRADERFPLCSTFKALAAAAILARVD -RAEESLERRMTYAQADLDAYAPVTGRHVADGMTLADICAAAVVWSDNTAGNLMLRALGGP -EGVTAFARAHGDTLTRLDRTEPTLNTAIPGDPRDTTTPAAMLGLLEAVLLGEALSPASRA -RLAGWMTESPTGAKRLRAGVPADWQVADKTGTGENGTANVVALVRRPGGAPLLASVYLTG -SPAEPDARNALHAEVGRLIARTf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F86945F ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTLLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. OV084 TaxID=1882777 RepID=UPI0008BDC7FB ---SAEAQLAALESASGGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERST -KDSGLLSRNISYSKADLVAYSPITEKHIATGMTVAAMCAATVQYSDNAAANLLLKVLGGP -PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD -QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pasteurii TaxID=2587529 RepID=A0A5P1KAW6_9ENTR --dTLQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -LQQDAKSRKEVLAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=A0A209A3W8_YERIN ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LKKAAEPRRDVLAAATKIVLAH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BEDB623 ---TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGVLLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVID-- ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000470FDC ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMGDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium grahamii CCGE 502 TaxID=990285 RepID=S3I2C2_9RHIZ --dEINRRMEALEKEIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRIVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -RLAAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVLWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. SCN 67-85 TaxID=1660152 RepID=A0A1E4IVX1_9BURK ---SAEAQLAELERACGGRLGVVAFNTASGARL-QHRPHERFPFCSTFKLMLSAAVLERSA -KDASLLSRRVVYSRADIIPNSPVTEKHVADGMTVAALCAAAIQYSDNAAANLLMKVLGGP -ADVTAFARTIGDQAFRLDRWETELNTAIPGDLRDTTTPAAMADSVQRLVLGDALGAAQRS -QLQTWLLGNTTSAERFMAAVPPGWKVGDKTGGGSYGTNNDVGVMWPPAGAPLVVSVYLTF -PDKDAKTRNDVVASAARIAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1L4A9_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000978902F --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010300F17 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4G2W9_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AC298C --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00027FCE6F ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMCTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. viciae TaxID=387 RepID=A0A4R0CBX1_RHILV ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAILDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNSVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q2YHY7_KLEPN ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVMIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A127SJH6_9BACT ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=A0A6B2GWP2_9RHIZ ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D74461B ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RP93_9BACT ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 42MFCr.1 TaxID=1048680 RepID=UPI0003637824 --dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYLTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Kluyvera intermedia TaxID=61648 RepID=A0A1X0XGT3_KLUIN -hpATQESAKQAEDQLNARVGYAELDLASGQMRgSYRPQERFPMMSTFKVLLCGAVLARVD -AGQEQLARRIQYRQQDLVEYSPVTEKHPTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKTGDRVTRLDRWETALNEALPDDERDTTTPEAMAQTLRQLLTGKILTPASQQ -QLMAWMEADKVGGPLIRSVIPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRIVVIYLTG -TKATMDERNKKIADIGDSLIKHw ->[subseq from] UPI0011C34229 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0011C34229 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D74085C ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-45 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A515L5V3_ENTCL -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDKPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Oligotropha carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) TaxID=504832 RepID=B6JGD8_OLICO --qDFEAKIRLIEGKVKGRLGVTALDTGSQRRF-EYRADERFAMCSTFKLLAAAAILKRVD -EGQEQLARRVRYTASDLVTYSPVTEKHIADGMTLAELCEAAITLSDNTAGNLMLAAIGGP -AGLTAYARTLGDSLTRLDRIETALNEAAPGDARDTTVPAAMAADIRKLLFGDALASASKD -QLKTWLLANKTGDMRLRARLPAGWRVGDKTGSGERGTTNDVGFLLRPAASPIIVAAYLTE -TAAPMSARNEALAAVGEAVAAAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodospirillales bacterium URHD0088 TaxID=1380394 RepID=UPI0012DDC9A7 -----AERLAGLEAGGGGRLGVAILDTADGTYL-GRRADQRFALCSTFKLLAAAAVLQRVD -DGAERLDRRIAFTAQDLDAYAPVTKKHVGPGMTLVELCAAAVEWSDNTAANLLLQTIGGP -AGLTGYARTLGDTVTRLDRTEPALNSAIPGDERDTTSPAAMLQDLRRLLVEDALSPASRQ -RLEGWMRQTKTGTKRLRAGLPAGWRVGDKTGTGENGTTNDVAILRPKGRAALLAAVYLTE -MPGPAARRDAVHAAIGRLVAETf ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root411 TaxID=1736530 RepID=A0A0Q7C1W3_9BURK ---SAEAQLAELERASGGRLGVAGFHTGSAARI-QHRAHERFPLCSTFKLMLAAAVLEHSA -KDASLLARRIGYGKADLVSWSPITEKHMADGMTVAELCAATVQYSDNGAANLLLKMLGGP -ATVTAFARGIGDQAFRLDRTEPELNTAIPGDLRDTTTPAAMSDSVQRLALGDALGTAQRE -QLKDWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPLVLSVYLTF -PQKDAKGRSDVIASATRIVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas brassicacearum TaxID=930166 RepID=A0A423H5I1_9PSED ---ELYKQLAELESSAKGRLGVALINTANGHDI-QYRGGERFPFCSTFKLMLAAAVLHKSM -AEPGVLDKHIAYGEADLLSYAPIAKQNLKQGMSVAQLCAATLQYSDNTAANLLIKELGGV -AAVNQFAKSLGDPAFRLDRKEPELNTAIPDDPRDTTTPAAMAASVQKVVLGDALATAQRE -QLAIWLKGNTTGDASIRAGTPTGWVVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ -LQKDAEARRDVLASATRLVMAH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q7X4G3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGL -AGLTAFLRQIGDNVTRLDRWETELNEALPADARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7B447_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGERCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEF3A18 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas halocynthiae TaxID=176290 RepID=UPI0004217BE3 --nELINSVRQIEANLNARVGIAVYDLESKRNW-QYHADDRFPLSSTFKTLACAALLQQAD -TGQQQLAQTVTFTESELVSYSPVTEAFVGTEMTLSALCEATLSMSDNSAANFILDAIGGP -QAVTQFARSIGDNVTRLDRWETELNEAIPGDERDTTTPNAMAMNLEKLVLGEALSPASRQ -QLKHWLTNNQVGDALFRASVPDDWTVADRTGAGGYGSRSIAALLWPPQRKPVVATLYITE -TEASFEDRNAAIAEIGAAIVT-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1V2HAU8_BACCE --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-56 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6C0VU04_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax cattleyae TaxID=80868 RepID=A0A1H0SY22_9BURK ---ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYRKSDLMEYSPETERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LALTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTRGEALSAAARA -RMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDAGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAAIARVGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP07_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGNAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-38 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G3C0M5_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Carbapenemase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A075X1C7_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase KPC-3 n=25 Tax=Gammaproteobacteria TaxID=1236 RepID=B9VVU9_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. M47T1 TaxID=1179778 RepID=I4N6C4_9PSED --------FQALESNLGGRLGVWALDTATGATL-GYREEERFAFCSTFKVMLAGAILHRNE -QQPGLLQQRIAYRQGQLVSYSPVTERHVATGMTVAQLCAAGLQYSDNTAANLLLGVVGGT -AVLTAFARSLNDPAFRLDRYETALNSALPGDVRDTTTPRAMASSLQHLALGDGLAAPSRA -QLQQWLRGNTTGEARIRAGVPSGWAVGDKTGSGDYGVANDVAVIWPAARAPWVLAVYTRA -TARNAQPRSEVIAEATRLVVKAw ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. arracaciae TaxID=487851 RepID=A0A2S6ZP74_9XANT ----LRAQWAEIERRTGGRLGISLLDTGTGRRI-GQREDERFPLCSTFKFVLAAAVLQQVD -QGKLALAQRVTIRAADMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLLPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGIDTRNDIAIVWPPGRAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00036B8E49 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLDRRVSYGKDRLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Phytobacter ursingii TaxID=1972431 RepID=A0A0G3QHV2_9GAMM -hpATQESVKQAEDQLNARVGYAELDLTNGQMRgSYRPQERFPMMSTFKVLLCGAVLARVD -AGQEQLARRIQYRQQDLVEYSPVTEKHLTDGMTMAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKTGDRVTRLDRWETALNEALPGDERDTTTPEAMAQTLRQLLTGKILTPASQQ -QLMAWMEADKVGGPLIRSVIPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRIVVIYLTG -TKATMDERNKKIADIGDSLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacterales bacterium CwR94 TaxID=2025587 RepID=A0A2I0G0U2_9GAMM ---TTVDKVKQVEHQLNPRVGYAEIDLSSGQLLqSYRAHERFPMMSTFKVLLCGAVLARVD -AGKEQLGRRIHYRQQDLITYSPVTEKHLDRGMTVAELCDATITLSDNTAANLLLTALGGP -QALTTFLRSTGDGITRLDRWEPELNDALPGDPRDTTTPAAMAQTLRQLLTGNSLSEASKQ -QLLRWMEEDKVAGPLLRSVLPKGWFIADKTGAGERGSRGIIAALGPDGKPSRIVVIYLTG -SSANMDERNQKIAEIGDALIKNw ->[subseq from] Beta-lactamase class A n=2 Tax=Paenibacillus TaxID=44249 RepID=A0A1G7MSA9_9BACL --nQVHQQFVQLEKKYDARLGVYAIDTGTNQSI-TYRSNERFAHASTFKALAAGVLLQQNS ---IKQLDKVITYTKDDLVEYSPVTEKHVDTGMKLGELAEAAVRFSDNTAGNLILKELDGP -KGFEKALRQIGDQVTHADRFETELNEAAPGDIRDTSTPQALADDLKALTVGNALPPDKRK -LLTDWMRGNATGDKLIRAGVPKDWEVADKSGAGGYGTRNDIAIIWPPNRAPIIIAVLSSR -DKKDAAYHNELIAEAAKVTMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia glumae TaxID=337 RepID=UPI000F5E171F ---AARRQLAALDASFGGRIGVAALDSGSGARL-LHRADERFAFCSTFKTVLVAAVLTRAA -GDPRLLSSVIRYRRQDLVRYSPVSERHVETGMSVAGLCAAALQYSDNSAANLLIRMLGGP -AAVTAYARSIGDRWFRLDRLETDLNDAVPGDERDTTTPAAMLETLRRVTLGDALDAAGRA -RLVGWMLGNTTGDARIRAGVPAGWRVADKTGSGDYGSANDVAVIYPPRRAPIVLAVYTTR -DRKGAGYDNAAIASAARIVTAAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SJS TaxID=1423321 RepID=A0A176J6D6_9BACI ----TGQKFMQLEKKFDARLGVYAIDTSTNHTV-VYRPDERFAYASTFKALAAGVLLKQNS ---IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREISDAAIRYSDNTAANLLLQELGGP -NGFEKGLRGIGDKVTEADRFETDLNSAIPGDIRDTSTARALATSLKAFTVDDVLPNDKRT -ILTDWMRRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPDRDPIIIAILSTR -DTKDATYNNELIAKAAKVALNSf ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00062C9472 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI0013F617AB -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGSVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -APATMDERNKQIAAIGATLVTHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus (strain EPS) TaxID=595537 RepID=E6UY86_VARPE ----AFAQLAALERASGGRLGVVGFNTATGARV-QHRADERFPLCSTFKLVLAAAVLGRSA -KENGFLARRVNYTKGDLVTYSPITEKNVATGMTVAELCAATVQYSDNGAANLLMKMLGGP -AAVTTFARSAGDDVFSLERWETELNTAIPGDLRDTTTPAAMAASVERLVLGNALGAAQRE -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVLAVYLTF -PDKDAKGRNDVVASATRIAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A2T3YB89_9BURK ---DLARQLARIEAQAGGRLGVAILDTASSKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEAAITRSDNTAANLLLDSIGGP -AALTAFARSIGDRVTRLDRNEPSLNEATQNDPRDTTTPAAMLADLRALLLGEHLSSASRE -QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVVWPEGRAPVLVVAYLTG -ATATATQRDAAIAQVGALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1T2Q3L5_BACCE --qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIIN-- ->[subseq from] Beta-lactamase n=1 Tax=Haemophilus parainfluenzae TaxID=729 RepID=G9BBW8_HAEPA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRLEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F2B0519 ------EQITLSESQLAGRVGYVEMDLASDRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Chelativorans sp. J32 TaxID=935840 RepID=UPI000484C232 --qAVSDRLALLEKRSGGRLGVAILDVRTGLMA-THRADERFAMCSTFKAIAAAAVLARVD -AGRDDLERRITYGKDKLIVWSPVTEKHAGGRMTLGALCDAAVTMSDNTAGNLLLESLGGP -EGLTAFFRSLGDDVSRLDRWEPDLNNVPPGDPRDTTTPAAMLRSLQKVVLGDALSQTSRQ -RLADWLIANQTGDARLRAGFPDGWRIGDKTGTGTT-VASDIAVAWTPEGATLLISAYLEA -PELSASDRDKIFKEIGEIAAE-- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000F054AE7 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAAL---- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YK09_9BACT ---DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD -EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -SGLTNFVRSLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDALSEASRR -QLEDWLQRNETGGPMIRAGVPKNWILGDKTGRGSNGATNDIAIMRPPDRAPILLAIYSVG -STATPTDRAAAVAEVAKIVAESf ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI0010AE3B0F -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSTSQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLIRHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000CCC5002 --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium mongolense USDA 1844 TaxID=1079460 RepID=A0A559SQW3_9RHIZ --dDIERRLAELEKRTGGRLGISVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGDENLERRVIYSQDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVAGP -KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNLALGSVLSEPSRE -KLIEWMLANTTGDARLRAGLPGAWKVGDKTGTGDNGSAADIAIIWPKGRGPILVTAYIAE -ATAPVKELNPVFAEVAKIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0009BA2A92 --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEGLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -DGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLTPVFADIGRTAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. CF316 TaxID=1144317 RepID=J1EJC0_9BURK ----WLAELQRIEASVGGRVGVAALDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD -QGHDKLDRRITYARKDLVTHSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP -PALTAYVRSLGDSITRLDRNEPSLNEARPGDPRDTTTPVAMVHCIQALALGQALSPASRD -KLQGWLLANKTGDKRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPPERKPIVVSCYLTG -GEAPPEQRDAAMAEIGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A485TCF8_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDKVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4KXH0_BACCE ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWKVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATKIVLD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009F08B86 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELXAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Verrucomicrobium sp. BvORR106 TaxID=1403819 RepID=UPI00056DD302 ------SKLEGIEGPDGARLGVYALDIESGMEV-KHRSEERFPVCSTFKMILTSAILKQSV -QDAGLMTRRISYAKEELVTYSPVTEKHVKDGMTVEALCAAAMQYSDNTAANLLMKILGGP -GAVTAFARSIGDSQFRLDRWETELNTALPGDPRDTSSPAAMGHSLRKLALGDGLPETQRA -KLVEWLQGNTTGDKRIRVAVPPDWKVGDKTGSGDYGTANDVAILWPPGRKPIVLAIYHTQ -KAADAKWQNEVIAAAARVVLEAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4RZE1_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASTAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALI--- ->[subseq from] Class A beta-lactamase Bla1 n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=A0A6B3KL77_9BACI ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A3P8IYB9_RAOTE -heATVNQVKTAERQLEARVGYAELDLASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEQLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAAPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNRQIAGIGETLIKHw ->[subseq from] Beta-lactamase KPC-12 n=2 Tax=Enterobacteriaceae TaxID=543 RepID=F2XNH2_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELEMNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001012F88F -------------RQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus dauci TaxID=1567106 RepID=UPI00061905CE ---SLASSFRMLEQQHQARLGVYAIDTGTGKVV-AYRHNERFAFASTYKALAAAAVLQQNS ---IADLDRVITYSAKDLVEYSPVTEKHVDTGMTLREICEAAIQYSDNTAGNILFQELNGP -AGFQQALRQLEDRTTRSERIEPELNAAVPGDPRDTSTPRALARDLRLFTTGKVLSQDKRQ -LLAEWMKGNTTGDDLIRAAAPKGWIVGDKTGSASYGTRNDIAVVWPPGRSPIIITVLTSH -TDKNAKVDNELVAKATKMVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus dendritiformis TaxID=130049 RepID=A0A4R5YUD2_9BACL ---AAHREFAQLEKKFDARLGVYAIDTGTNQTV-AYRPNERFAYASTYKALAAGALLQQNS ---IDQLDEVITYTKDDLVEYSPVTEKHVAAGMTLGEIAEAAVRYSDNTAGNLLFKELDGP -KGFEKALRQIGDRVTQADRVETELNEAIPGDIRDTSTAKALATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAVVWPPNSAPIIIAILSSR -DKKDAAYNNELIAQAAKVTMNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00099535D2 --qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIIN-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-43 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A482GPY8_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLRKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. Lac2 TaxID=2594423 RepID=A0A6B0KUS1_9ENTR -heATVATVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG -TPASMDERNKQIAAIGKTLVAHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI0010343F80 -heATVATVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG -TPASMDERNKQIAAIGKTLVAHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderiaceae TaxID=119060 RepID=UPI0009F1A6D1 ----IRQRLKDIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAAAVLARTD -RGQEDLQRRIVFSQRDLVSYSPATSQHIRERMSVAQLCKAAITLSDNTAANLLLASMGGP -AGLTAFARSLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGERLSSSSKA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDRGTANDVAILWPPGRGPVLVAVYLTE -TSGNAARCNAAIANVGALVVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8826B --qATHKEFSQLEKKFDARLGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP -KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRE -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D83189 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSDAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q5GJ47_RAOOR -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTIGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] Beta-lactamase n=1 Tax=Massilia lurida TaxID=1036180 RepID=A0A562RKS1_9BURK -------DFAAIERDLGGRLGVAAIDLATGRIA-GNRQDERFPMASTFKATLAAAMLARDA -REPGFIDKRLRYTKADLLSYAPVTSKHVEDGMTVAELCAATVQLSDNTAANVLLKELGGP -QAVTAFARSIGDTTFRLDRWEPELNAALAGDARDTTTPLAMARTLQKLLVGDGLPAPQRR -QLNDWMIGTTTGDKRIRAAAPAGWQVGDKTGTGGYGSTNDIGIAYPPGRGPVVIAIYTHQ -PAKDAPVREDIVAAAARAAF--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia hayleyella TaxID=2152889 RepID=UPI0012912B05 ----AHASLAELERASNGRLGVFALATAGPTLL-SYRADERFPLCSTFKVMLIGAVLARSR -QTEGLLTQHILYGAGDLVAYSPITQPHAGNGMNVAALCAAALQYSDNTAANLLLNIVGGP -AAVTAFARAIGDDTFRLDRIEPELNTAVPGDPRDTSSPAAMARSLQRLVLGDVLGAPQRQ -QLNDWMRGNTTGHARIRAGVPAAWPVADKTGTGDYGTTNDIAVLWPTGLPPVVLAIYFTQ -HKQDAKMRDDMLAAVAQVLAATf ->[subseq from] Class A beta-lactamase LEN-27 n=1 Tax=Enterobacteriaceae bacterium 8376wD9 TaxID=2684233 RepID=A0A6B0EQV0_9ENTR ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8BT24_9BACT ---ELDRRFGQLEKTVGGRLGVATLDTGSGAGS-DHRAGERFPMCSTFKLLAVAGVLARVD -RGRERLDRRIAFSTADLLEYAPVTRARVAEGMPIADLCEAAITVSDNTAANLLLATLGGP -AGLTAYARSLGDNVTRLDRIEPALNEAVPGDPRDTTTPAAMLGDLKALLVGTALARASRE -RLIAWLVATKTGDRRLRAGVPAGWRVGDKTGSGEHGTTNDIGIVWPPGGGAVLVAAYLTE -TSRDTPACEAVLAGVGRMLA--- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=Q64HI6_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q5XPR7_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014420A3F ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSETFPMCSTFKALAAAFVLARAD -KGEENIDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus m1293 TaxID=526973 RepID=C2MKX2_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. TND4EL3 TaxID=1907311 RepID=A0A1N6TLC8_9BURK ---AAQTQLAALEQAAGGRLGVAAWRQGSEQRL-AYRADERFPLASTFKAMLAAAVLARSA -SQPGLLEQQVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTILGGP -QAVTAFARSIGNTVFRLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDSWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPGGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. 679 TaxID=2496119 RepID=A0A3S0AV21_9BURK ---SAEAQLAALESASGGRLGVVGFNTGSGARI-QHRPHERFPLCSTFKLTLAAAVLERST -RDSSLLSRHLNYSKSDLIAYSPITEKHVSTGMTVAAMCAATIQYSDNAAANLLLKELGGP -AAVTAFARGIGDQVFRLDRMEPELNTSIPGDPRDTTTPAAMSDSLQRLVLGDALGAAQRE -QLKTWLLGNTTNTERFLAGVPTGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVVASATRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R693 TaxID=1764276 RepID=A0A246TY13_9RHIZ --dEINRRMDALEKAIGGRIGVSAIDTDTNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTQGSALSEPSRD -KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVIWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102FA3F7 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLERRVTYGKDKLVDYSPLSEKHAGSDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F524155 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A3R7HSN8_9BURK --eAIRQRLAQIEVESGGRLGVSILDTMSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD -HGQEDLDRRVVFSNSDLVPYSPATGQHTRERMSVADLCKAALTLSDNTAANLLLASLGGP -AAVTAFARSIGDGVTRLDRNEPTVNEATPGDPRDTTTPGAMLGNLRELLLGERLSSPSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTG -TSGDAARSNAAIANVGALVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=Q4L201_RAOPL -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPAAMDERNKQIAAIGATLVTHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus MSX-D12 TaxID=1053222 RepID=J8DBE0_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00101C1C71 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSASSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000A17884D -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase LEN-34 n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00067205DE ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGIEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A126S6F1_PSEPU -hdPLRQAMQQLEAASGSIIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -TKQDAPWNSETIAAATRIVVEAw ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium brassicacearum TaxID=314235 RepID=A0A2P7BX07_9RHIZ ---DLSAAFKSLEEKTGARLGVSAHDTGSDNRI-GYRENERFAMCSTFKFLASAAVLARVD -RKEDKLDRMILVKKSDILPNSPATEKNAGKSMSLAALCEAAITLSDNTAGNLILDSLGGP -KGLTEYARGLGDATFRLDRWETELNEAKPGDPRDTITPVAILKDMQKIVLGDALSKSSRD -QLIEWLLANKTGGKRLRAGLPEDWSVGDKTGTSDSGMANDIAVIWPPDRKPILLAVYLYD -PKGTADSRNTIHKKVAALVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144219D9 ---NIERRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEATVTVSDNTAGNLLLESFGGP -AALTEWVRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q1WBU0_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGR------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus manliponensis TaxID=574376 RepID=A0A073JWR5_9BACI ----IHQGFVQLERKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAILQQNS ---IEKLNEVITYTEEDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNILFEELDGP -KGFERTLRQIGDKVTIADRFETELNEAIPGDIRDTSTPKTLATNLKAFTVGSALSADKRK -ILIDWMSGNATGDKLIRAGVPENWEVADKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQATKVTVN-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=101 Tax=Proteobacteria TaxID=1224 RepID=BLKPC_KLEOX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-26 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B2AIG7_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A0H4IUK8_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-30 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1S6KJP8_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A482M1W9_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase KPC-24 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4TDC5_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Class A carbapenemase KPC-2 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000181D380 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M4HN29_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDLWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D3JYW1_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. CA142267 TaxID=2050965 RepID=UPI000D6DDB80 --nTVEEQLNTLEKYSQGRLGVALINTEDNSQI-IYRGEERFAMASTSKVMAVAAVLKASE -KQAGLLDKNITIKKSDLVAYSPITEKHLTTGMTLAELSAATLQYSDNTAMNKILDYLEGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEQDAKYRKDIIAKAAEIVTK-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-20 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2C9PIR8_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax radicis TaxID=758826 RepID=A0A561BDN3_9BURK ----WLAELKRIEASVGGRVGVAALDTHTGRQI-AHRGSERFPMASTFKLLLAAQTLRRVD -QGHDKLDRRITYARKDLVTHSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP -PALTAYVRSLGDSITRLDRNEPSLNEAKPGDPRDTTTPVAMVHCIQALALGQALSPASRE -KLQGWLLANKTGDKRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPPERKPVVVSCYLTG -GEAPPEQRDAAMAEIGALVAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax avenae TaxID=80867 RepID=F0Q2B9_ACIAP ---ALARAVQEIEASVGGRLGVALLDMATGRQR-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGKSDLMEYSPATERHVGGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSSAARA -QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7HZA9_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtARRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A9H5_SHISO -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERIRQIAEIGA------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A163LUA3_9BACI ---DLDETFATIESDYDARVGVYAIDTGSDETI-DYRSEERFAFASTYKALAAALVLKQNT ---MEKLEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQKFLREIGDDVTQSDRYETALNEFIPGNTRDTSTPAALATSLQGFAVGDLLTDDKRA -RLLDWMKGNATGDTLIRAGAPDGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH -DTEDADYDDALIAEVAEVTLK-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus sp. CD3 TaxID=1921565 RepID=A0A5J6RWQ9_9GAMM --nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWVIGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ -QEQDAKYRKDIIVKATEIVTKPf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A561MCE8_9BURK ----IRQRLKDIEAESGGRLGVSIVDTTSGLNA-GLRTDERFPMCSTFKLLAAAAVLARTD -RGQEDLQRRIVFSQRDLVSYSPATSQHIRERMSVAQLCKAAITLSDNTAANLLLASMGGP -AGLTAFARSLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGERLSSSSKA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDRGTANDVAILWPPGRGPVLVAVYLTE -TSGNAARCNAAIANVGALVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q4L200_RAOOR -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A127T5V1_9BACT -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] Beta-lactamase n=1 Tax=Mycetohabitans endofungorum TaxID=417203 RepID=A0A2P5KC24_9BURK ------EALAVLEARMSGRLGVCAIDTGSGARL-VHRAEERFPFCSTFKAVLAAAVLARSG -DTPDWLSQRVRYGSADVVSYSPISGQHVGAGMRIDEMCAATLQYSDNTAANQLMKVLGGI -DAVTAFARSVGDATFRLDRWEPELNTAIPGDVRDTSTPAAMADTLRAVMLGNVLRPWQQQ -RLQQWMLGNRTGDKRIRAGVTAQWRVADKTGTGEYGTTNDIGVLWPPGRAPIVLSIYFTQ -PQQDAPARDEAIEHATRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY77_KLEPN ------EQITRSESQLAGRVGYVEMDLVSGRTLaAWRANERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIAEKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPASMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia rhizoxinica TaxID=412963 RepID=E5AR55_PARRH ------EALAALEARMRGRLGVCAIDTGSGAQL-VHRAAERFPFCSTFKAVLAAAVLARSG -DTPDWLSQRVRYGLADVVSYSPISGQHAGDGMRIDEMCAATLQYSDNTAANQLMKVLGGP -DAVTAFARSVGDATFRLDRWEPDLNTAIPGDVRDTSTPAAMANTLRAVMLGDGLRPWQRQ -RLQQWMLDNRTGDKRIRAGVPAQWRVADKTGTGEHGTTNDIGVLWPPGRAPIVLSVYFTQ -PRRDAPACDEAIEQATRIVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q939H5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAVITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=UPI0011A9C5B0 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKGAIYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000522FD2F ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGNTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTVGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=B6D1Z4_ACIBA ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAAKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=5 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GMX3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0007756FE9 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSAEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLH-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=A0A379FDS5_PROVU ---TIEEQLSTLEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE -KQAGLLDKHMTIKKTDLVTYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP -SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPLAMATSLQLLTLGDALGQYQRQ -QLITWLKGNTTGDQSIKAGLPNNWVVGDKTGSGDYGTTNDIAIIWPENQAPLILVVYFTQ -QKQNAKPRKDIIVKATEIVTKEy ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces spinoverrucosus TaxID=284043 RepID=A0A4Y3VL17_9ACTN -------RYAALERRHGARLGVFALATGTGATL-NYRADDRFALCSTFKALAAAAVLHEHP ---LSHLNQRVTYTRAELQSYSPISEDHIETGMTVRELCDAAVRYSDNTAGNLLMRDVGGP -AGLTAYLRGLGDKVSRMDHYEPELNGMAPGDPRDTTTPRAIATTYRDLVLGDALTPDRRA -LLKDWLVRNTTGAKRIRAGVPKGWTVADKTGTGEYGRANDIGIVWPPHTEPLVLAVMTDR -SGHDTPPREALLAEATRLVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A142FK12_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVARLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEDF5A4 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVCD-- ->[subseq from] Carbapenemase KPC-2 n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=G8HAR0_PSEAI -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. YR266 TaxID=1884386 RepID=UPI00089803D1 ---SAEAQLAALESASGGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERGT -KDSGLLSRNISYSKADLVAYSPITEKHVATGMTVAAMCAATVQYSDNAAANLLLKVLGGP -PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD -QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASATRIAVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001443A7D9 --qATHKEFSQLEKKFDARLGVYAIDTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=2 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000C7D9149 ------EQITLSESQLAGRVGYVEMDLASDRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIAKIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0012997D37 ------EQIKLSESQLAGRVGYLEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=UPI00129C4EB9 --pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYLTE -SQATMEERNRQIAGIGATLIQHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5A93C ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010308B20 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD -RLVAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=UPI000A0572A8 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0008FE64BA ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIGHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella sp. YJ TaxID=1850565 RepID=UPI000A18D793 -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLHHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLVTHw ->[subseq from] class A beta-lactamase n=1 Tax=Thalassospira sp. MIT1004 TaxID=1882733 RepID=UPI0008DD15F3 --dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD -LGTETLDRRIIYGVEDLVTYSPTTEKHVNGGMTIGELCEATLHLSDNTAANLILDTLGGP -DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium altiplani TaxID=1864509 RepID=A0A109JJA7_9RHIZ --dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITPSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI0004593F0D ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAE -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -RLADWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A2Z4N5Z5_9ENTR ---ETLVKVKDAEDKLGARVGYIELDPNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMRTTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRCALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM2297 TaxID=754762 RepID=J0VYI5_RHILT ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEAKKDDPRDTTSPDAMLDTLGNLTLGSILTEAACD -RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATASAKELNPIFAEVGKMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium sophorae TaxID=1520277 RepID=A0A2P7ATM7_9RHIZ ---DLAAAFKTLEEKTGARLGVSAHDTGRDSRI-EYRENERFAMCSTFKFLASAAVLARVD -QRQEQLDRMILIKKSDLVAYSPVTEKYVGKPMSIEAICEAAVTLSDNTAGNLMLDTLGGP -KGLTKYARSLGDATFRLDRWETELNEAKPSDARDTITPAAILKDMQKTVLGDALSKSSRD -QLVEWLLGNKTGDKRLRAGLPKDWSVGDRTGTSDSGMANDLAVIWPPDRKPILLAVYLYD -PKGTADSRNTIHKKVAALVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. M47T1 TaxID=1179778 RepID=UPI0009DA4111 --------FQALESNLGGRLGVWALDTATGATL-GYREEERFAFCSTFKVMLAGAILHRNE -QQPGLLQQRIAYRQGQLVSYSPVTERHVATGMTVAQLCAAGLQYSDNTAANLLLGVVGGT -AVLTAFARSLNDPAFRLDRYETALNSALPGDVRDTTTPRAMASSLQHLALGDGLAAPSRA -QLQQWLRGNTTGEARIRAGVPSGWAVGDKTGSGDYGVANDVAVIWPAARAPWVLAVYTRA -TARNAQPRSEVIAEATRLVVKAw ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005DB3E8F ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRD -QLALWLKGNTTGAAAIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LKKAAEPRRDVLAAATKIVLAH- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q0GM99_ENTGA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAKPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADTSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK068 TaxID=2512130 RepID=A0A4R1YBI6_9RHIZ --dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRVVYDQDKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDSMVDTLGNLTLGSALSEPSRD -KLVEWMVANTTGGARLRAGLPDAWKIGDKTGTGNNGSAADIAIAWPPGHGAILVAAYVTQ -AKAPASEINPIFAEVGKIVAD-- ->[subseq from] Broad-spectrum beta-lactamase SHV-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0000EFE329 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMVSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWATELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Methylobacterium platani TaxID=427683 RepID=A0A179S0S6_9RHIZ ---DATARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAIAAAAVLARVD -KGRDDLNRRISYGRDALLSYAPVTSKHVETGMTLAELCAAAVVWSDNTAANLMLDTLDGP -GGITAFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGQALSAESRA -RLIGWMQESTTGLKRVRAGLPEGWRTGDKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIARSf ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-42 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A411KB40_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPAGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2B0W9N6_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNIIFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00076616EE ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLMQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6Y6_9BACT ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -IGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter gillenii TaxID=67828 RepID=A4KCT8_9ENTR --pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITE -SQATMAERNRQIAGIGATLIQHw ->[subseq from] class A beta-lactamase n=1 Tax=Neptuniibacter pectenicola TaxID=1806669 RepID=UPI000832DE18 -hrSLIQTVERIAGEIEAQVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD -AGQESLDRRVSFSESDLVTYSPITEKHAGGQMSLADLCEAALTMSDNTAANLVLQALGGP -EKVTLFARGLGDDVTRLDRWETELNEAVPGDNRDTTTPNEMVKNLQNLLLGDVLSRKSRD -QLYDWLKRNQVADGLFRAAVPEGWIVADRTGAGGFGSRSITAIFWPPERQPIVVALYLTQ -TEASFSERNKAITEIGEAIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI00047F5CC4 ---TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLIVAGAILARVD -RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE -TAGDAARCNAAIASVGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora auratinigra TaxID=261654 RepID=A0A1A8Z4V4_9ACTN -----EHAFRQLEERFDARLGVYAIDTGTGRTV-QYRADERFAYASTFKALAAAEILDETT ---DAELDRVVRYSADDLVTYSPITEQHVAEGMTLRAIADAAVRYSDNTAANLMFRHLGGP -QKIEKELREIGDKVTDPARYETELNEARPGDRRDTSTPRALAHDLRAYAVGNALDPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDADYDNALIAEATKAALADw ->[subseq from] class A beta-lactamase n=1 Tax=Methylocapsa sp. S129 TaxID=1641869 RepID=UPI00131EB64E ---RANDEIAALEAREGGRLGVAVLDSASGLSL-AHRAEERFPMCSTFKLLAAAAVLSRVD -AGSEQLDRKVPYGAADLLEYAPVTKAHLADGMSVGDLCAAAIDWSDNTAANLLLQIIGGP -AGFTGYARSLGDSVTRLDRNEPTLNTSIPGDERDTTTPLAMARAMQAVLLDKKLSEASRR -QLEAWLMGDKVGDKRIRAGLPPSWRIGDKTGSGDNGSTNAIAIIWPPDRAPLLATVYYTG -STASVDARNGVHKDIGAIIAKTf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A0F73B4 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGE--SRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Erwinia sp. ErVv1 TaxID=1603299 RepID=UPI0008335E7A ----IQQKLAVLEKNAGGRLGVALIDTADNSQV-AYRGDERFPLCSTSKVMAVAAVLKKSE -ADDNLLQKRLAIKTSELVNYNPITEKHLNSGMTLGELSAAALQYSDNTAMNKLVGYLGGP -AKVTDYARSLGDALFRLDRTEPTLNTAIPGDARDTTTPVAMADSLRKLTLGHALKAAQRT -QLIEWMKGNTTGSESIRAGLPASWSVGDKTGSGDYGSTNDIAVIWPENRAPVILVTYFTQ -PRQDASSRKDVLAAAARIAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UHP6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD9_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYPQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A3S2VHD7_RHIML ---DVTERLRRLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGREVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGNLLLESFGGP -EGLTSWLRSIGDETTRLDRTEPELNEARKGDPRDTTTPAAMLDTLGKLVLGPVLSQEGRQ -QLIDWLVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIAVAWPQGRGPILICVYMGE -AKAPLGDLNPVFADIGSIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517IA09_BREBE ---AMDQKFAALETKFDARLGVYAIDTETDVVV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADATIRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTMSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLSSEKQT -ILIEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIIIAVLSSR -DKQDATYDDALIAEATKVAVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0009B5696E --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNKAPIILAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A367X640_9PROT --dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD -LGTETLDRRIIYGVEDLVTYSPTTEKHVDGGMTIGELCEATLHLSDNTAANLILDALGGP -DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI0013977C6F -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLIRHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010318498 ----IDLRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRIIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B0FTU2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASXRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas frederiksbergensis TaxID=104087 RepID=A0A1J0EFU1_9PSED ---ELYNKLAELESSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM -AESGLLEKHIAYGEADLLSYAPIAKQNLKQGMSIAQLCAATLQYSDNTAANLLIKVLGGV -AAVNQFAKSLGDPAFRLDRWEPELNTAIPDDLRDTTTPAAMAASVQKVVLGAALATAQRE -QLATWLKGNTTGDASIRAGTPAGWVVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ -HQKDAEARRDVLAAATRLVMSH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0G3ICX4_KLEPN ------EQIKLSESQLSGRVGMIEMDLVSGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8XGV6_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALASAFVLARAD -KGEENLDRRVSYGKDTLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D1624BC ---ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001368BA11 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTALLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVQPAGWFIADKTGAGERGARGIVALLGPNNKAGRIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kirstenboschensis TaxID=1245436 RepID=UPI000B01DBD1 ---TIRARLQEIEADSGGRLGVSIVDTASGLHA-GLHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVSNSPATSKHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRNEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTG -TAGDAARCNAAIADVGVLVAQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF8_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -RLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Variovorax TaxID=663243 RepID=UPI00089614F9 ---SAEAQLAELERTSGSRLGVVGFNTGSGARV-QHRPHERFPLCSTFKLMLAAAVLERST -KDGSLLSRNLSYGKSDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -AAVTAFARGIGDQVFRLDRMEPELNTSIPGDPRDTTTPAAMSDSLQRLVLGDALGAAQRD -QLKTWLLGNTTNTERFLAGVPAGWKVGDKTGAGSYGTTNDVGVLWPPAGAPIVLSVYLTF -PRKDAKGRNDVVASATRIAA--- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A371UQF3_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLLDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATKIVLD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00132F604E ------EQIKQSESQLSGRVGMIEMDQASGRTLtAWRADERFPMMSTFKVVLCGAVLARGD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1IDR9_BACCE ---TVNHSFAKLEKEFDAKLGIYALDTDTNQIV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDKLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI6_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPHLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii (strain WSM2304) TaxID=395492 RepID=B5ZUP0_RHILW --dNIQKRLAALEKRTGGRLGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGLVLARAD -KGEESLDRRVTYGKDKLVDYSPLSEKHADADMTITELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPKLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLSEASSD -RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIME-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI001431B246 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVEIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPARAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00040EE991 --dDVTERLRQLEERTGGRLGVAVLDTETNISF-GHREAERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTVAELCEAAITISDNAAGTLLLESFGGP -QGLTSWLRSIGDETTRLDRTEPDLNEARKGDPRDTTTPGAMLDTLGKLVLGPVLSQEGRK -QLIDWLVANKTGDARLRAGLPQDWRIGDKTGTSMTGAVSDIAVAWPEGRGPILICVYTGE -AKAPLDDLNPVFADIGRIVAD-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8T1_9BACT ---SIAKKLSKLETSFDGQIGILAINTANNQRI-QYRADERFPIQSTFKVMAVSAILKQSM -TDKHLLQQKVTYTKQDLVFWSPITEKHLADGMTISELCAAAMMYSDNTATNLIVKKLGGP -SAVTTFARSIGDNTFRIDSWEPELNSN-SSDPRDTSTPTAMEKSLQKLTLGNVLASPQRE -QLVTWMKGNTTGDARIRAGVPKGWIVADKTGAGDYGISNDIGIIWPPSCAPIVVTIYSVH -NNKDTARRDDVIASATRMLIHEf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP12_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -TGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Methylobacterium TaxID=407 RepID=A0A0C6FFB3_9RHIZ ---DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD -KGQDDLNRRISYGRDDLLSYAPVTSKNVETGMTLAELCAAAVVWSDNTAANLMLATMGGP -AGITAFARAHGDGVTRLDRTEPTLNTAIAGDPRDTTTPAAMVGLLDNVLLGQALSAESRG -KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDTLHAEVGRLIARSf ->[subseq from] UPI0011C34287 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0011C34287 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. YR752 TaxID=1884383 RepID=A0A286AZS7_9BURK ---SAEAQLAALESASGGRLGVVGFHTGSGARI-QHRPHERFPLCSTFKLMLAAAVLERST -KDSGLLSRNISYGKSDLVAYSPITEKHIATGMTVAAMCAATVQYSDNAAANLLLKVLGGP -PAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMADSVQRLALGDALGTVQRD -QLQTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASATRIAVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A3C72FE --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000975E02A --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=Q2YHX9_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BFD3909 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATKIVLD-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D01D65 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQRLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013BCCA3F ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas oleivorans TaxID=1735121 RepID=A0A2T5G341_9SPHN ---ALNARIARIEAESGGRLGVFLLDSGSGPRF-GYRARELFPMCSTFKFLLAAMILARVD -RGKERLDRRIRFGPEAIVTYAPITGKHVGGDMSIAELCEATMTLSDNVAANLLLDTIGGP -TALTAWLRTIGDKVTRLDRNEPSLNEARAGDPRDTTTPLAMLGNLRKLLIGRTLSAPSRA -LLTSWMVGNRTGDRRLRAGLPSGWRVGDKTGTGENGTYNDIAIIWPPERPPLLMTAYLTQ -ARPD--RGDATLAEVARAMAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=A0A290HL33_9PSED -hdPLRQAMQQLEAASGSIIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHRNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGRAPWILVVFSRG -TKQDAPWNSETIAAATRVVVEAw ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. 1180 TaxID=2587049 RepID=UPI00119BED18 ---SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST -RDGSLLSRNLIYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -ATVTAFARGIGDQTFRLDRTEPELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000E0F08A8 ---EIDRRIGELEKRIGGRIGVSAIDTETNVSF-GYRETESFPMCSTFKVLAAGMVLSRVD -KGQENLERRIVYDKDKLVTYSPETEQHVGGEMSVGELCKAAITLSDNTAGNLLLESIGGP -KELTNWLRTLGDGSTRLDRWETDLNEAKKGDRRDTTTPDAMLDTLGNLALGSVLSEPSQN -TLVEWMVANTTGAARLRAGLPESWKIGDKTGTGNNGTAGDIAIAWPPGHGPILIATYVAE -AQVPVSEINPIFAEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. RP3T TaxID=2135446 RepID=A0A2T3VNW1_9ACTN -----EQAFRQLEERFDARLGVYAVDTGTGRTV-QYRADERFAYASTFKALAAAEVLDGTT ---DAELDRVVRYSADDLVTYSPVTEQHVATGMTLRAIADAAVRYSDNTAGNLMLRHLGGP -QKFEKELRGIGDKVTDPARYETALNEARPGDRRDTSTPRAMAGSLRAYTVGTALEPADRD -TLNGWLRGNTTGGELIRAGVPAGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAILSSR -DQEDADYDNALIAEATKAAVADw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI00104A2918 -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGATLVRHw ->[subseq from] Class A beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A5Q0MA57_VARPD ----AGAQLAELERACGGRLGVAGFHTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPAAMSDSVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] Beta-lactamase KPC-4 n=5 Tax=Enterobacteriaceae TaxID=543 RepID=B1PL86_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium ENNIH2 TaxID=1920109 RepID=A0A2I8QHC4_9ENTR ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SALTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE -TQATMDERNKKIADIGASLIKHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella planticola TaxID=575 RepID=UPI0010D25799 -hqATVTTVKQAESQLQGRVGYAELDLASGQLLaGYRSDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTDGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAERIVVIYLTG -TPATMDERNKQIAAIGVTLVTHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBA01F --dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRMLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLAAWMEANTTGAARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=UPI000D5F7C7C ---ALENELAAIEAQAGGRLGVAMLDTANGQTR-GWRMHERFPMCSTFKLLLASAVLTRKD -RGKEDLARKVVYTQAQVVSYSPLSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP -PALTAFARGIGDPLTRLDRNETTLNEAIPGDPRDTTTPAAMLADMRALLLGERLSAGSRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDRGTANDIAIIWPAGRAPLLVTTYLTG -ATASPAQRDAAIAKVGAWVAK-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D616_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSPRSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae (strain 342) TaxID=507522 RepID=B5XQY6_KLEP3 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSPRSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium 228 TaxID=2083153 RepID=A0A2S5KL09_9PROT ---GLAEAVRNGERKLQGKIGVSLLDTDTGMGW-SHRGDERFAMCSTFKVLACSAILKQVD -DGRLSLTQRLTFNQQDVVSYSPISKAFAGKPMSLGEICHAAMTYSDNTAANLIISQLGGP -QAVTDFARSIGDGVSRLDRWETALNTAIDNDPRDTTTPEAMTSNLQRLLLGDVLSTASQQ -QLGQWLRDNTTGGSRIRKGIPETWQVGDKTGSGDNGTANDVAILWPPGQKPLLLSIYITQ -AKADWNACSAVIAGISAAIAAEy ->[subseq from] Beta-lactamase n=1 Tax=Serratia rubidaea TaxID=61652 RepID=A0A1L2F514_SERRU --pATLDTIKDAESRLHGRVGYAELDLVSGKMMdSYRSDERFPMMSTFKVILCGAVLARVD -AGQEQLDRRIRYRQNDLVEYSPVTEKHLAEGMNVGELCHAAITMSDNTAANLLISTLGGP -SGLTAFLRKTGDSVSRLDRWETALNEALPGDERDTTTPESMARTLHNLLTGDALSAESRR -QLMRWMEMDNVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG -TKATMDERNKQIADIGAALINHw ->[subseq from] Class A beta-lactamase n=1 Tax=Edaphobacter sp. 12200R-103 TaxID=2703788 RepID=A0A6B9YYE1_9BACT --eDLAQEFAKIEAGSKGRLGVAVA-LPSGSRM-QHRGEERFPMCSTFKFLAASLVLQRVD -AGREHLDRQVSFSKNDLVTYSPETEKHAGGSMSVAELCKAALTLSDNTAANLLLASFGGP -PAVTGFARSIGDTMTRLDRTETSLNEATPGDPRDTTTPNAMLRNLEKILLGAVLKPSSRK -RLTEWMLANTTGKAKFVAGLPPDWKVADKTGSGEHGSNNDIGVLYPPSGRPVLVASYLTE -TEISNDERNAIHAEIARAIA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=UPI000A00B47B ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTKSDRLETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG9_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILkSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYPQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000F8D3824 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B52E4F ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDKVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A097BQY7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERCARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Acidobacteriaceae bacterium KBS 146 TaxID=639030 RepID=UPI000553155B --dDLAAALAAAEAKSKGRLGVAIL-FPSGKRM-AHRGDERFPMCSTFKFLAASLVLQRVD -QGKERLDRAVKYSRSDLVEYSPETEKHAGGSMTIAELCKAALTLSDNGAANLLLASFGGP -PAITAFARSLGDTMTRLDRTETTLNEAIPGDPRDTTTPNEMVANLKKIFFGTVLKTDSRK -QLADWMLANTTGKTKFVAGLPADWKVADKTGSGSHGSNNDIGVLYPPTGKPILIASYLTQ -TAISTEERNAIHADVARAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=L7QJB7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERMSQIVDMGGSLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF9259A -----KHHFVKLEDKFDARLGVFALDTGTNQTV-TYRADERFTYASTSKALAVGALLQQKT ---IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP -NGLEKALRDVGDNVTMPEQFEPELNEVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGEPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. DB0501 TaxID=2709665 RepID=UPI0013EA3F95 ---DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPMCSTFKAVAAAAVLARVD -KGQDDLNRRITYGRNALLSYAPVTGKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP -AGITAFARAHGDTVTRLDRTEPTLNTALAGDPRDTTSPAAMVGLLDNVLLGRALSGDSRA -KLVGWMQESPTGLKRVRAGLPDGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDAVHAEIGRLIARSf ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEEDFFD ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium ENNIH1 TaxID=2066051 RepID=A0A2I8QFX2_9ENTR --pATLESVKQAEDQLNARVGYAELDLANGQMRgSYRPQERFPMMSTFKVLLCGAILARVD -AGQEQLARRIQYRQQDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQTLRQLLTGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRVIVIYLTG -TQATMDERNKKIADIGASLITHw ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000939A028 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGAANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=BLAC_PROVU --nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAILKESE -KQAGLLDKNIIITKSDLVAYSPITEKHLATGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ -QEQDAKYRKDIIVKATEIVTKEf ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia aggregata (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614) TaxID=384765 RepID=A0NLL2_LABAI ----LEKTVQDAESRLSARIGVAVLDSETGKTF-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPDRRVKIRKEDLVSYSPVTEKKVGSGMTYLELCDAAITISDNAAANLVLEAVGGP -QGLTDYLRGIGDTITRLDRTEPALNEGQAGDSRDTTTPAAAVATLQKLVLGDALSPSARD -QLTGWLLDNQVGKATLRAGLPEEWPVADKTGAGGNGSRNNIGVIWPDDRQPVVIAVYITQ -TDASFDDRNKAIADIGAALAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=A0A640JJY9_9BURK ---DAETQLAELERACGGRLGVSGFHTGSGARL-QHRAHERFPLCSTFKLVLAAAVLERSA -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVNEMCAATMQYSDNAAANLLLKVLGGP -AAVTAFARRIGDTTFRLDRTEPELNTSIPGDPRDTTTPAAMSDTVQRLALGDALGAPQRE -QMREWLLGNTTSTERFLAGVPKGWRVGDKTGAGSYGSTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000FBC16B7 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFAQ-HGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD5_9BACT ---ETLVKVKGAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain AH187) TaxID=405534 RepID=B7HS58_BACC7 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=A0A1R1QG29_9BACI -------DFAKLEDQFDARLGVFAWDTGTSETI-AYRADERFAYASTHKALAVGALLQKKS ---IADLDKRITYTREDLVNYNPITEKHVDTGMTLKELCDASLRYSDNTAENLILKQLGGP -AGLKKSLREIGDNVTNPERFEPELNEVKPGETHDTSTPRALAESLQTYTIGDALPKEKRS -MLIDWLKRNTTGDTLIRAGVPKGWEVADKTGSGSYGARNDIAVIWPPKGDPIVLAILTSR -DQKDADSNDKLIAQAAKEVIETf ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D1632D0 ---ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGQSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX82_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ZX81_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BF62D19 ---TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0003735CAF ---TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00103B981E ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAN -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus pseudomycoides TaxID=64104 RepID=C3BTF1_9BACI ---TVNHSFTKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRE -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVID-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. Root473 TaxID=1736541 RepID=A0A0Q7LRS7_9BURK ----AQAQLAELERACGGRLGVAGFHTRSGARL-QHRAHERFPLCSTFKLMLAAAVLERST -TDASLLGRRISVGKGDLVSHSPVAEKHLATGMTVREMCAATMQYSDNAAANLLLKVLGGP -AVVTAFARRIGDTTFRLDRTEPELNTAIPGDPRDTTTPTAMSDSVQRLALGDALGAPQRE -QMCEWLLGNTTSTERFLAGVPAGWRVGDKTGAGSYGTTNDVGVLWPPSGAPLVLSVYLTF -PDKDAKGRNDVVASATRIAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Undibacterium sp. B2R-29 TaxID=2528175 RepID=UPI00138A0276 -----RQELARLEKSFSGSIGVYLLDPHTRRHF-SYQGEKRFAFCSTFKALLGAAILHKSS -QDGDLLEREITLNSSDFVTYSPVTEKHKDGSMRIADLCAATIQTSDNTAANALLRELGGP -AALTAYMRSIGDNAFRLDRWETELNSALPGDLRDTSTPSAMANSLHKLVLGNALAEPQKH -MLKEWLIGNTTGNTRIRAGLPQGWLVGDKTGTGDYGSAHDIAVVWPPSRAPFVLAIYTCR -KKKDSEARSDIIAEVTRVLVQQw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sp. Sh_2011b TaxID=1076164 RepID=G3ESI3_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRELLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGVIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGA------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q1WBU1_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGA------ ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000DE624C6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMDADKVAGPLLLSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001030FF05 ----IDLRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFADVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 9120 TaxID=1500897 RepID=UPI000551541C ---TIRRRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLAAGAVLTRVD -RGQEDLARRVVFSQRDLVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARDLGDGITRLDRIEPMLNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSSSSRA -QLLAWLVANETGGARIRAKLPQEWGVGDKTGTGDHGTANDIAILWPPGRGPVLVAVYLTG -TNGDAARCNAAIAEVGALVVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. TaxID=1912094 RepID=A0A2E2T5W8_9PROT --dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD -LGTETLDRRIIYGVEDLVTYSPTTEKHVNGGMTIGELCEATLHLSDNTAANLILDALGGP -DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0009BAB105 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -APASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00104070FB ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TPVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. 369 TaxID=1705714 RepID=UPI000F7F0C7E ---SAEAQLAELERASGGRLGVAGFNTGSGVRL-QHRAHERFPLCSTFKLMLAAAVLERST -RDGSLLSRNLSYGKGDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -ATVTAFARGIGDQTFRLDRTETELNTSIPGDPRDTTTPSAMSDSIQRLVLGDALGAAQRD -QLKTWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Phytobacter ursingii TaxID=1972431 RepID=UPI001158A877 -hpATQESVKQAEDQLNARVGYAELDLTNGQMRgSYRPQERFPMMSTFKVLLCGVVLARVD -AGQEQLARRIQYRQQDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQTLRQLLTGKILTPASQQ -QLMAWMEADKVGGPLIRSVIPTGWFIADKTGAGGRGSRGIVAALGPDGKPTRIVVIFLTG -TQATMDERNKKIADIGASLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA8959 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8HZD4_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D3A62B2 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSVANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodospirillales bacterium 69-11 TaxID=1895825 RepID=A0A1Q3UZN6_9PROT ----AEETFAMLEAQSGGRLGVAALDTGSGRQF-GTRATERFPLCSTFKLLLAGSVLARVD -AGQEKLDRIVQFTRAQLVPYSPATGPAADGPMRVGALCEAAVTLSDNTAANLLLGSMGGP -AGLTRFIRSLGDEVTRLDRTEPTLNEAVPGDPRDTTTPADMVRDMQRLVLGDALSRASRG -QLVTWLRANKTGDKRLRAGVPPGWQVGDKTGTGERGTANDAGILWPPGGAPILVAAYLTG -ATRTPAERDATLAGVGRIVAA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI00057802A2 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEVAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Neorhizobium sp. P12A TaxID=2268027 RepID=UPI0011ED946F ---DADKQLAELEKKTGGRLGVAVLDTETNISL-GYRENERFFMCSTYKALAAGFVLARAD -KGEEKLDRRVMFGKDALVSYSPVTEKHAGTDMTVAELCEAAITMSDNTAGNLLLDSFGGP -SALTAWLRATGDDETRLDRREPDLNEAKKGDLQDTTTPDSMLDTIGLLTLGDTLSEASRN -HLIDWMVADKVGDARLRAGVPKDWKIGDKTGTGNNGALGDIAVIWPPDRGPFIVAVYIAE -ATAPMKDLNDVFAAVGKLV---- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A3S3ZWP3_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Micromonospora TaxID=2617518 RepID=A0A2G6XDN6_9ACTN ---DWDHEFRRLEERFDARLGVYAIDTGTGQTV-QYRADERFAYASTFKALAAAEILDETT ---DAELDRVVRYSADDLVTYSPITEQHVAEGMTMRAIADAAVRYSDNTAANLMLRHLGGP -QKFEKELRKIGDKVTDPARYETELNEGRPGDRRDTSTPQAMAGSLRAYTVGDALEPSDRD -TLNGWLRGNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPNRAPIVLAVLSSR -DEKDADYDDALIAEATKVVMASw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) TaxID=358681 RepID=C0Z7D8_BREBN ----MDIKFAALEKQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDGVTKSERYETELNEAKPEDTRDTSTPKALATSLRAYTVGNALSSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKIVVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Massilia albidiflava TaxID=321983 RepID=A0A411WZK6_9BURK --------FSDVERDLRGRLGVAVIDTATGKTT-GHRLGERFPMCSTFKAVLAAQALAREA -REPGFLARRLRYAKADLVSHSPITGKHVDTGMTVADLCAATVQYSDNTAANALMKELGGP -AGLTAFMRGLGDTQFRLDRWETELNTAIPGDDRDTTTPWAMARTLEKLVIGDALPAPQRQ -QLKDWLLGNTTGGKRIRAAVPAGWQVGDKTGTGAYGVTNDIGIVYPPGRAPLVVVIFTHL -AEKDGDNRDDIVVAAAR------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0U3A6C6_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKQLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf106 TaxID=1736255 RepID=UPI000B1B3F02 --rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAVLARVD -RGEDGLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMDGP -AGLTGHIRGFGDSTTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPQDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG -ARTSSEARSATIASVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf93 TaxID=1736249 RepID=A0A0Q4XFK2_9RHIZ ---DLAGRFASIEEASGGRLGIGLLDTGSGAHA-AHRGDEHFPLCSTFKVLAAGAVLARVD -RGEDRLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP -AGLTGHIRGFGDATTRLDRTEPDLNEAASGDPRDTTTPLAMAETLRRLVLADALSPASRA -LITAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRAPLVLTVYLTG -ARTSPEARSATIASVARAVA--- ->[subseq from] Beta-lactamase n=2 Tax=Bordetella bronchialis TaxID=463025 RepID=A0A193G5K4_9BORD -------EYAALEQSHRRRLGVYAVDTGSGQEV-AYRAGERFAFCSTFKAILAAAVLAQDA -GKPGLLRQRVAYTKSDLVSYSPVTGEHAGAGMTIAELCAAAVQYSDNTAANLLLHRLGGP -AALTAFARQAGNASFRMDRYETQLNTAIPGDERDTSTPADMAGLLRALVLGDALPAPARA -QLKTWLVGNKTGAQRIRAAVPGGWAVGDKTGTGDYGSANDIGIIWPPSRPPIVMAIYTGS -RDKRAKADEGLIAEAARIAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia silvatlantica TaxID=321895 RepID=A0A2V4TUB7_9BURK ---SLEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMQERFPMCSTFKVLLASAVLTRKD -HGKEDLARKIVYSPAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP -AAITAFARSIGDPVTRLDRNETTLNDAIPGDPRDTTTPAAMVANLRELLLGERLASVSRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIIWPTGRAPILVTAYLTG -ATASPAQRDAAIAQVGV------ ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. fragariae TaxID=487822 RepID=A0A2N9D6I3_9XANT ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI000B7AE852 ---TLKSQFETLENKSGGRLGVMVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium grahamii TaxID=1120045 RepID=A0A370KTR4_9RHIZ --dEINRRMEALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRIVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLAAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVLWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVTD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii TaxID=386 RepID=A0A3E1BUP3_RHILT ---NIEKRLVALEKRTGGRLGVSVLDTQTSISF-GYRGDEAFPMCSTFKALAAGFALARAD -KGEESLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPAKELNPAFAEVGRMIVE-- ->[subseq from] class A broad-spectrum beta-lactamase OKP-B-40 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE71B9D ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI000459C232 ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -RLAGWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPVLISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A147GUH3_9BURK ---EAEAALQALDAGFDGALGVFALDTGTGATL-GHRAAQRFPMCSSFKAVLAAAMLGRSV -RQPGWLAERVRYTRAELVPYSPITERHVGEGMTVAALCAATVQYSDNGAANLLMARSGGP -QAVTAFARSQGDTVFRLDRIEPALNTAEPGDERDTTTPEAMARLLQRLVLGDGLPPPQRG -QLADWLRGNTTGARRIRAGMPALWTVGDKTGTGRHGSASDVGVVWRPGAAPLVLAVYTTR -PQPDAPADEAVIADAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AD24 TaxID=1528693 RepID=UPI000B5DFCBD ---AIRQRLAQIEAESGGRLGVSIVDTSSGLHA-GLRTDERFPMCSTFKVLAAGAVLTRVD -RAQEDLARRVVFSQRDLVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLATFGGP -AALTAFARDLGDGITRLDRIEPTLNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSSSSRA -QLLAWLVANETGGARLRAKLPQDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVAVYLTG -TNGDAARCNAAIAEVGALVVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1D3RIG5_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDSGMTIGEIAEAAIRYSDNTAGNILFNKIGGP -KGYEKALRRMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -NEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sp. AG TaxID=2681969 RepID=UPI0012EB5E43 ---AIKDDFAKLEDKFDSKLGVFALDTGTNQTV-VYHPDERFAYASTHKALAVGALLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASIRYSDNTAANLILKELGGP -TGFKKILDEIGDNVTNPERYEPELNEVNPGETYDTSTPRALATSLQAFTLGDTLPAEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGSGSYGTRNDIGIIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005E457E3 ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWPAKGAPLVLVVYFTQ -LKKAAEPRRDVLAAATEIVLAH- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A0D0MS60_VARPD --qDASAQLAALEAASGGRLGVVGFNTATGARV-QHRADERFAFCSTFKLMLAAAVLERSA -KEGGLLARRVNYSKGDIIANSPITEKNVATGMTVADLCAATIQYSDNAAANLLMKVIGGP -PAVTAFARSSGDDAFRLDRWETELNTAIPGDLRDTTTPAAMAASVERLVLGNALGTSQRE -QLKTWLLGNTTSKERFVAGVPAGWKVGDKTGAGSYGTNNDVGVLWPPAGAPLVLAVYLTF -PEKDAKVRNDVVASATRIAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Paracraurococcus ruber TaxID=77675 RepID=UPI001057FE9F ------DAVARIEAASGGRLGLAVLDTGSGARL-AHRGAERFPLCSTFKLLAAAAVLARVD -AGEEWLDRLVRFGREALVTYSPATEPQAGGPMTLAALCEAAMTLSDNTAGNLLLAAIGGP -EGLTAFARRLGDPATRLDRIETTLNEARPGDPRDTTTPAAMLADLQALLQGDALSPAGRA -QLLAWLEGTRTGDTRIRAGLPAGWRFGDKTGSGDNGTTNDVGLFWPPGRPPVLFAAYLTQ -TAAPTDQRNATHAAIGRALA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=A0A3T0I6A4_9BACI ---QIHRKFADLEHKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTFKALAAGALLQHYS ---LDQLDELVKYSREDIVTYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLNKLGGP -KGFETALRQIGDNVTQADRYETELNSAVPGDTRDTSTPKALAASLRAFAVSDLLSAEKRT -ILIDWMKGNATGDALIRAGVPNGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Marinobacter hydrocarbonoclasticus TaxID=2743 RepID=A1TZK3_MARHV ---SLIKTVKKVADDLEARVGFAAYDLESGQRW-EYHADQRFAMSSTFKTLACAALLHRVD -TGQANLARKVNVSESDLVTYSPITETYADGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLGDALSEPSRE -QLRDWLEGNQVADGLFRAAVPEGWVVADRTGAGGFGSRSITAVIWPPERQPIVVALYLTQ -TDASFAERNAAIAEIGEAIV--- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YLB6_9BACT ---DAAARIAAIETRIGGRIGVAALDTSNDKHHlEYRAKERFPMCSTFKFLAAAAVLQRVD -EKKEKLERFVPYNAKDILEYAPVTKEHLNEGMTLGALCQAAIEQSDNTAGNLLLNAIGGP -AGLTDFVRTLGDRVTRLDRIEPELNSAIPGDERDTTTPAAISSDMQRLLLGDSLSETSRR -QLDDWLQRNETGGPMIRAGVPKTWSVGDKTGRGANGATNDIAIMRPPGRAPILLAIYSVG -STATANDRAAAIAEVTKVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0G8BZB2_9BACI ---TVNHSFAKLEKEFDAKLGIYALNTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGEVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=A0A328XQT9_9BURK ---ALENELAAIEAQAGGRLGVAMLDTANGQTR-GWRMHERFPMCSTFKLLLASAVLTRKD -RGKEDLARKVVYTQAQVVSYSPLSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP -PALTAFARGIGDPLTRLDRNETTLNEAIPGDPRDTTTPAAMLSDMRALLLGERLSAGSRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDRGTANDIAIIWPAGRAPLLVTTYLTG -ATASPAQRDAAIAKVGAWVAK-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000D13AFDE ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2DE94A ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMSATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATALRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium gnaphalii TaxID=1010610 RepID=A0A512JEH2_9RHIZ -----EEVFAQIERSVGGRLGVAALEAGTGRGL-RYRAGERFPLCSTFKLLAAAAVLSRVD -AGQESLERRIAYTASDLVDYSPTTAARVTEGIPLADLCEAAITLSDNTAGNLMLSRIGGP -SGLTRYLRERGDTVTRLDRTEPALNEALPGDPRDTTSPDAMVANLDRFVLGDALATSSRA -RLQEWLLANRTGATRFRAGLPPDWRVGDKTGTGERGTANDVGLLYPPDGAPILAAVYLTE -STGSPEQRNASIAQVARTIAN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RKK2_9BACT -------QIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas parafulva TaxID=157782 RepID=UPI00041D9E9D ---DIDSDLSTVEHSFKVTLGVWAIDTASGKTV-AYRAEDRFAFCSTFKVILAAAILAKSA -EDQALLDRRITYAPDQLVTYSPITEQHVQAGMTVRELCAAALQYSDNTAGNLLLELVGGP -AGLTAYARTLGDPVFRSDRNEPSLNTALPGDPRDTTTPLAMGVTLQKLLLGSALGEDARQ -QLQGWLKGNTTGDKRIRAGVPQGWLVGDKTGSGDYGVANDVAVVWPPGKAPWIVVVFSRA -EAKASEWNNDAIAASMKAVA--- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-37 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346ARK9_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRRELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QLVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI0006B304C0 ---ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGTLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0P0IUA6_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGHTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1J1E8D3_LYSEN ---ALRARLAELEKRSGGRLGVSALDTADGRRF-DVRGDERFAMCSTFKFLLAAAVLRKAD -RGELDMQQRLAVPKSALISHSPITTPIAEAGASLAQLCEATMTISDNAAANLLLPLVGNP -AGLTRFLRGIGDSVTRLDRNEPELNTALPGDPRDTTAPNAMLASMRTLLLGDALSAASRR -QLTDWLIANQTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPQGRKPVFITTYLTQ -AQGEDDARSAILADAARALAQHw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BFL9_BREBE ---AMDQKFAALENKFDVRLGVYAIDTETDVVV-AYREDERFAFASTYKALAAAAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATNLRAYTVGDVLSSDKQT -ILIEWLKGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5F280 --nDINRQLASLEKRTGGRLGVSVLDTKSNASF-GHRQDERFAMCSTFKALAAAFVLARVD -KGQETLGRRIVVSKADLHAHSPVAEKHVGNGMTVGELCDAAVTYSDNAAANLILASFGGP -AGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMMRTLGKLLLEDVLSPSSRD -QFAAWLVANRTGDRRLRAGLPAKWTIGEKTGTSGHGEAGDVGFMRPPKGQTILASVYIAE -APKPVKELEPIFAEVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Azohydromonas sp. 13393 TaxID=2590212 RepID=UPI0012FCF95F ---ALSRALPVMEERLGARLGVHILDTHTGHQW-THRAGERFPMCSTFKVLACAAVLARVD -AGADNLKRRIRFQGSDLVTYSPVTEPHAGRELLLSELCEAAMTRSDNTAGNLILRSLGGP -AAVTAFARSLGDEATRLDRWETALNEARPGDPRDTTTPAAMSTCLQALVLDQRLAPESRG -QFVRWLLANRTGDARLKAGLPATWRIGDKTGSGDFGTANDVAVIWPPGRSAVIASVYITQ -TVASFDDRNAAIAEIARVL---- ->[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3LN01_9BURK ------DAWAAIERSSGGRLGVAVMQ-ADGRID-GHRLDERFPMCSTFKWLAAAHVLHRVD -RGEERLDRRIRYGREVLLPHSPVTERHVGDGMTLAELCHATITISDNAAGNLILASFGGP -AGLTRYARGLGDEVTRLDRWETELNEARPGDPRDTTSPRAMARLLHATLVGDALSPRSRT -QLAQWLEATSTNGQRLRAGLPPGWRMGSKTGTGARGTTNDVGIYWPPGRPPVVVAVYLTQ -SEAPEAARNGAVAQVARRVH--- ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia sp. BL8N3 TaxID=1938808 RepID=A0A4R1IIP0_9BURK ---SVDARFADLERASGGRLGVCAIDTANGAQI-SYRSDERFPFCSTFKLMLAAAALAHGT -LVAGFMQQRVRYARRDLVTYSPVSSRHVESGMTVEELCAAAIQYSDNTSANLLMNMLGGP -AAVTAFARSIGDAEFRLDRRETELNTAIPGDARDTSTPAAMAQSVRALCVGDALPAPQRA -QLQDWLRGNTTGAKRIRAGVPPGWQVGDKTGTGERGTANDVGVLWLAARKPVVLAVYHTQ -QVVHAQPNDAIIAAATRVVMRAf ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000F23DDE8 ------EQIKQSESQLSGRVGMIEMDLASGRAD-RRRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BP57_KLEPN -------KVKDAEDQLGARVGYIELDLNSGKIXeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGXXQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRXLCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIXDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium 65-37 TaxID=1895711 RepID=A0A1Q3KN46_9PROT ------SKFSDLEARNGGRLGVAAFDTTSGRRV-GHRSDDRFPICSTFKLPAAALVLARVD -RGEEQLGRRVVYSEKDIVVNSPVTASHAGAGLSMAELCEAAMTQSDNTAANLMLASFGGP -AALTAYLRSLGDMTTRLDRIEPDLNEALPDDPRDTTTPAAMVATMERLLLRAVLSASSRK -MLTGWLVANKTGDKRLRAGLPADWRVGDRTGTGANGTANDVAIVWPGDDPPILMAVYYTG -STISDEARNTVVAEAGSIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE3_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYAPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEE463E ---AMYKNFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -NEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonadaceae bacterium SCN 68-20 TaxID=1660161 RepID=A0A1E4LJ31_9BURK ---ALLRALRGIEQGVGGRLGVAALDTGTGRLA-AHRGGERFALCSTFKLLLAAQALHRVD -RGVEQLEHRIAYGQADLLEYAPVTRPHAGGALTVAELCEAAMAWSDNTAANLLLARQGGP -QALTDWLRTLGDPATRLDRNEPALNDVPPGDVRDTTTPEAMARTLQAVALGEALTPASRE -RLQGWMLGCRTGDQRLRAGMPPGWRIGEKTGTGPRGTSNDIGVLWPPGRAPVALACYLTG -STADGARRDAAIAEVGRRVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. X2(2017) TaxID=2025586 RepID=UPI000BA84313 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A2S4FQU5_9BACI ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144219AC ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSG -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4ZEF9_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E19A05 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNQ -GKEDAKYDDKLIAEATKIVLH-- ->[subseq from] Beta-lactamase n=1 Tax=Idiomarina aestuarii TaxID=624146 RepID=A0A2T4D0J2_9GAMM ---RLLDAIHTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD -RESETLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP -DVLTAYLRDIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLFGDALSLESRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIAAIYITQ -TSASMGERNAAIADLGQEIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. Cy-639 TaxID=2608360 RepID=UPI0014206914 --nSLQRQLQQLEHAAGITLGLWALDTGSGKRL-AYRADKRFAFCSTFKAVLVGAVLHKSQ -TDPKLLERQIPYDIGQLVVYSPVTEKHTGAGMTVAELCAAALQYSDNTAGNLLLELVGGP -AGLTAFARRLGDPSFRLDRNEPTLNSALPGDPRDTTTAQAMGVTLQRLLLTNGLPAGAQD -QLRDWLKGNTTGDSRIRAGVPQGWVVGDKTGSGDYGVANDVAIIWPKGRAPWILVVFSRA -QEKSAAWNSEVIAQATRVVVDTw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MZ04 TaxID=2559236 RepID=A0A4R9EYL7_9ACTN ---EARRRLRELEKDYPGRIGVHALDTGSGATV-GHREHERFAIASTFKVLAAAEILRRAD -KEPGLLDVLVEYTRDDLVTASPRTELHLETGMTVRELCDATITYSDNAAANLLMRRMGGP -AGITAFARSLGDSRTRLDRWEPELNTNIPGDPRDTTTPAAMTENLRRLVLGDALHPLDRG -QLTRWLLENTTGDKRIRAGLPKGWRVGDKTGTPAYGGVNDVAVTWPPDRAPLVISVYTTR -LDPDTPGEDRIAEDITRVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102F6903 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGNTRLDRTEPTLNEGQKGDPRDTTTPDAMLDTVGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010324A59 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGSDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGNTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTVGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL53_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYXQNDLVEYSPVTEKHXTDGMTVRELCSAAITMSDNTAANLXLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAXIGASLIKH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF4F68C ---TVNHSFAKLEKEFDAKLGIYAFDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IENLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -NEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFTLGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0013CB744D --dNIERRLAALEKRTGGRLGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGFVLARVD -KGEESLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSILTEASSD -RLIAWLVASTTGGERLRAGLPKEWNVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE -ATAPAKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia alba TaxID=311410 RepID=A0A0M6Z0S0_9RHOB ------ETAQDVENRLSARIGVAVVETETGRTW-NYRGDERFPLNSTFKAFLCAALLDAGD -KGEIDLAQSVTVHDSDLVAYSPVTEKRVGGDFTLLELCEATATISDNAAANLVLKELGGP -DSLTRFMRRIGDKTTRLDRFEPELNSAIPGDERDTTTPLAAASSLQKLLLGDELTAASRK -QLTSWLVGNKVGTSTLRAGLPKEWIVADKTGAGDYGSRSNIAVIWPENRAPVVIAVYITQ -TKASFEDRNRAIADIARALVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4BC2C5 --qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Class A beta-lactamase Bla1 n=2 Tax=Bacillus albus TaxID=2026189 RepID=A0A654SAU5_9BACI --qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014423394 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENIDRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD8F174 --dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -EELTKWLRTLGDRSTRLDRWETALNEAKDRDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYLTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Caballeronia glathei TaxID=60547 RepID=A0A069PUZ8_9BURK ---SVDARFADLERASGGRLGVCAIDTANGAQI-SYRSDERFPFCSTFKLMLAAAALAHGT -LVAGFMQQRVRYARRDLVTYSPVSSRHVESGMTVEELCAAAIQYSDNTSANLLMNMLGGP -AAVTAFARSIGDAEFRLDRRETELNTAIPGDARDTSTPAAMAQSVRALCVGDALPAPQRA -QLQDWLRGNTTGAKRIRAGVPPGWQVGDKTGTGERGTANDVGVLWLAARKPVVLAVYHTQ -QVVHAQPNDAIIAAATRVVMRAf ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. TNe-862 TaxID=416944 RepID=A0A1G6HBN2_9BURK -hgALEKQLAAIEAQTGGRLGVAMLDTASGRAQ-GWRMHERFPMCSTFKLLLASAVLTRKD -HGGEDLARKIVYSHAQVVSYSPVSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP -AAVTAFARSIGDPVTRLDRNETTLNEAIAGDPRDTTTPAAMLADMRELLVGERLSAASRE -QLIAWLVANQTGDARLRAGLPKDWRTGDKTGTGDHGTANDIAIVWPVGRAPILVATYLTG -ATASPAQRDGAIAKVGAVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium anhuiense TaxID=1184720 RepID=UPI0007BE9995 --dDIQHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSSFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGTDMTVAELCEAAVSVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVTELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141ABF4F ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A5C1G375_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVKAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000409F1E7 --tEIKADFAKLEDQFDAKLGVYAVDTGTNQTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAQNLILKQIGGP -DSLKKALREIGDDVTNPERYEPELNEVNPGETHDTSTAKALAKSLQAFALEDTLPKEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGSASYGTRNDIAIIWPPKGDPIVLAILSSR -DQKDAKYDDKLIAEAAKEVIKAf ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Yersinia pseudotuberculosis TaxID=633 RepID=UPI00067B8013 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase KPC-10 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C6JUP9_ACIBA -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHZ0_KLEPN ------EQITLSESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDERLDRRIRYPQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHALSDRSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPAAMAERNQQIAKIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Marinobacter TaxID=2742 RepID=A0A5P9EKB4_9ALTE -hnALIKTVEKVADDLEARVGFAAYDLESGQRW-EYRADQRFAMSSTFKTLACAALLHRVD -TGQANLARKVNVSESELVTYSPITEKHADGEMTLSDLCEATLTTSDNTAANLVLRELGGP -EAVTSFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVRNLQTLLLDDALSEPSRE -QLRDWLEGNQVADGLFRAAVPEGWTVADRTGAGGFGSRSITAVIWPPECQPIIVALYLTQ -TEASFEERNAAIAEIGEAIV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=A0SXM1_SALTM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1Y6B165_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q6REX4_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus mucilaginosus (strain KNP414) TaxID=1036673 RepID=F8F5G2_PAEMK ---SAKQPFAQLESEYKARLGVYAVDTGTGRTI-EYRPDERFAYASTFKALACGAVLKAKP ---LEGLEDRVTYTSGELVTYSPVTEKHVSTGMTLRELCDAAIRYSDNTAGNLLLKQLGGP -KGFEAALKEAGDAVTKAERYETELNEAVPGDDRDTSTPRALASSLRAYTLGDALSADKRD -VLTDWLRRNTTGGELIRAAVPEGWVVGDKTGAGSYGTRNDIAVIWPPDGPPIVMAVLSSR -DTKDSAYDNALIAKAAKAALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromonas hydrophila TaxID=644 RepID=A0A649UHL3_AERHY --------IKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLAIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UIF6_ACIBA ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D614_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPVSMAERNQHIAGIGAALIEHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2ACA57 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPVSMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas oryzae TaxID=1608942 RepID=A0A5B2TK97_9PROT ----LEGAFARIEAEVGGRLGVAVLDTGGGHYA-GHRADERFPLTSTFKLLAAAATLARVD -AGKERLDRRVRFGRDKLVTYSPVTEPHAGGNMTVAALCEATVTLSDNTAGNLLLEGLGGP -AGLTQWLRSIGDSTTRLDRWETALNEARPGDPRDTTTPAAMLGDLQLLLLGEVLSAGSRA -RLTQWLRDNKTGDARLRAGLPQGWQAGEKTGSGGLGSTNDAGLIWPPGGAPVLVAAYLTG -SAAPLAAREAALAGVARAIT--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011559FC9 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBB966 --dEINRRMDALEEAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDDDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Stigmatella erecta TaxID=83460 RepID=A0A1I0L484_9DELT -------RLAELERRHGGRLGVAVLDTASGARV-LHRADERFPLCSTFKFLAAAQVLARVD -RGEEQLGRRIVFSEADLVSYSPVTKEHVGGDMTLEAICEAAITLSDNTAGNLLLDSFGGP -AALTRYVRTLGDRKTRLDRRETELNEAKPGDPRDTTTPAAMLQDMQRLLVGDALSAGSRE -RLVAWLTASKTGAKRLRAGVPPDWRAGDKTGTSGNGVVNDIAIFWPPDRAPLLVSAYYRG -PEG---TGDAVLEAVGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium bangladeshense TaxID=1138189 RepID=UPI0007E5BB87 ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEVSCN -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3YA68_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JS97_9ACTN -------EFGHLEAKFGARLGVYALDTGSGRTV-EHRANERFAYASTFKALAAGAVLAETS ---TAELDQVVRFTAADLVTYSPVTEKRVETGMSLRELADAAVRYSDNTAGNMLLKRLGGP -DGLERALRGLGDRTTDPERTETSLNEATPGDTRDTSTPRALVGDLRAYVLGEALDAEDRA -VLTGWLRSNTTGDKLIRAGVPAGWVVGDKTGSGGYGTRNDIAVVWPPDREPIVLAILSTR -DKQDATYDDALIAEAARVVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. HB1 TaxID=1678678 RepID=UPI0006B3EDCB ---AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -GGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV -QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG -TAGDAARNNAAIANVGALVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE4_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNGERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A2A6FZA2_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase OXY-2 n=1 Tax=Methylobacterium bullatum TaxID=570505 RepID=A0A679J068_9RHIZ ---DLADRFAQIEEASGGRLGIGLLDTGSGTQA-AHRGGERFPMCSTFKVLAAGAVLARVD -RGEDGLDRRLRYEPREVVPYSPVSGPRAGGEMTIAELCEVAVTLSDNTAANLLLGTMGGP -AGLTGHIRGFGDATTRLDRTEPDLNEAAPGDARDTTTPLAMAETLRRLVLADALSPASRA -LITAWLVGCRTGDARLRAGLPQDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTVYLTG -ARTSPEARSATIASVARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas massiliensis TaxID=522492 RepID=UPI00058D22E0 ------VALAALEREFNGRLGLCALDPRHGRAL-RWRADEAFPLCSTFKVVLAAAILKQVG ---LSGLGRRVRYQQSDLVTYSPVTEQHLATGMTLAELCAAGLQYSDNTAGNLLLREVGGP -AGLTAFARQLGDNSLRLDRWETELNSAIPGDPRDTTTPGAMAATLQTLLLGQGLDARLQA -QLTDWLLANTTGDARIRAGVPHGWKVADKTGSGDYGTANDVGVIWPAKDRPVVIALYSTQ -PAAAAEPRSDVLARMARIVAN-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-54 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9KGH5_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRSEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001030061A ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTYGKDKLVDYSPLSEKHAGTDMTIAELCEAAVIVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=A0A5P1YE31_STRTE -------NLTALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAALLDRRP ---GARLDERITYGAADLVPYSPVTEKHTGKGMTVRELCDAAVRYSDNTAANLMLRELGGP -RALTAYVRGLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPGAGRA -QLTDWLVRNTTGDRRIRAGAPRGWTVGDKTGTGEWGRANDAAVLWPGNGSPMVLSVLTER -PDRDAAASDELVAEAARRVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium aegyptiacum TaxID=1764550 RepID=UPI0007E59A51 ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD -KGDEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -KLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPAKELNPIFAEIGKMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BED92FC -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGALLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B500B7 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEEALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEEHFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Class A beta-lactamase SHV-179 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5N016_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMNTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I1X1_9BACL ---AMDQKFAALENKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFEAALRQIGDGVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGNVLPSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSKR -DKQDAAYDDALIAEATKIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus khanii NC19 TaxID=1004151 RepID=W3V4K1_9GAMM ---SLHQQLAELENRTKGRLGVTLINTANGQEI-QYRGNERFPFCSTFKLMLVAAVLHKSM -SQSELLAKHINYSESDLQSYAPIARKNLNQGMNITQLCAATLQYSDNTAANLLIKELGGL -AAVNHFAQGLGDRAFRLDRWEPDLNSAIPDDPRDTTTPAAMATSVKKIVLGETLAAPQRE -QLVGWLKGNTTGDASIRAGTPDGWVVGDKTGGGDYGTSNDVAILWPPEGSPVVLAVYFTQ -HQKDAESRRDVLASTTRLVMKH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BED7D9D -----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFTYASTSKALAVGALLQQKT ---IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP -NGLEKALRDVGDNVTMPEQFEPELNEVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGDPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A059X6G7_9BACT ---TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q6EH44_PROMI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAL-GPDGKPSRIVVIYTTG -SQATMDEANRQIAEIGASLIKHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-39 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G3MDR1_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSTIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter denitrificans TaxID=666685 RepID=A0A2W5MUQ1_9GAMM ------ERLRELERADGGRLGVAVLDTASGRFA-GWREDERYPMCSTFKFLLAGAVLARVD -RGEFGLDRRIPISRDDLIAHSPVTERHVGPALTVAQLCEATMTQSDNAAANLLLPLVGEP -AGLTAVLRSWGDATTRLDRPEPHLNDVPPGDTRDTTTPRAMTEHLRHLVLGNTLTPASRT -QLTAWLVANRTGDHRLRAGLPKDWRVGDKTGSGP-GTTNDVAVLWPPGRAPLLVAAYLTG -SPQADDRRNATLAAVAREIA--- ->[subseq from] Beta-lactamase n=1 Tax=Metakosakonia sp. MRY16-398 TaxID=2487150 RepID=A0A348DKF8_9ENTR ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE -TQATMDERNKKIADIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas entomophila TaxID=312306 RepID=A0A3S8UPE7_9PSED --sSLAHELEALEHSLDVTLGLWALDTGTGKIV-SYRAGERFAFCSTFKVVLAAAILAKSA -DDRGLLDRRITYSEDQLVVYSPVTEKHVGDGMTVSALCAATLQYSDNTAGNILLEQVGGP -VGLTAFARNLGDPAFRLDRNEPELNTALPDDPRDTTTPLAMGMTLQKLLLGNSLAEAGRL -QLQEWLKGNTTGDKRIRAGVPQGWVVGDKTGSGDYGVANDVAVIWPPGKAPWILVVFTRG -QQKASSWSNEAISSSARAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000B43A3BE -----NHDFAKLEEEYDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNQKVTYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAANLILTQLGGP -AGFKKALDKIGDHVTNPERFEPDLNEVNPGETHDTSTPKALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDTLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKEDPIVLAVLSSR -DKKDADYNDKLIAEATKVVIK-- ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=unclassified Raoultella TaxID=2627600 RepID=UPI00135A7F26 -heATVKQVKAAERLLEARVGYAELDIASGRLLtSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEQLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLSGSVLSAASRQ -QLRSWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMKERNRQIAEIGETLVKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus idriensis TaxID=324768 RepID=UPI0012B0C2F3 -----NHDFDKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAANLILKQLGGP -TGFKKALEEIGDNVTNPERYEPDLNEVNPGETHDTSTPRALAASLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLSVLSSR -DKKDADYNDELIAEATKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014414B05 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENIDRRVSYGKDKLVDYSPISEKHAGADMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. GZT TaxID=936600 RepID=A0A154B6A4_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAIYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=BLAB_PROVU --nTIEEQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPKNHAPLILVVYFTQ -QEQDAKYRKDIIVKATEIVTK-- ->[subseq from] class A broad-spectrum beta-lactamase OKP-B-34 n=1 Tax=Klebsiella TaxID=570 RepID=UPI000B40E904 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAVIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q5PU78_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAVIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Massilia armeniaca TaxID=2072590 RepID=A0A2R4CAG3_9BURK -------PFQRIEDRWGGRLGVAAIDTGNGAVV-GHRQDERFPFCSTFKTVVAAAVLARSV -TEPGFLDKRLRYTQADIKPHSPVSEKHVASGMTAAELCAATIQYSDNAAANILMRELGGP -AAITAYARSLGDTTFRLDRWETELNSAIPGDQRDTTTPLAMARTLEKLLVGDGLPPAQRQ -QLKDWMVGNTTGDTRIRAGVVKGALVADKTGTSGYGVANDIGVIYLPERAPIVLVVFTHG -TDERAEAQSEPVAEATRVAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF4_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEMHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H6UQJ9_KLEPN --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAIIWPENHAPLVLVTYLPN ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas cremoricolorata TaxID=157783 RepID=UPI0009DD54D8 ---SADSRFQRIEREHGITLGVFALDTGSGRQL-AYRADQRLPMCSTFKVMLAGAVLQRSQ -TERELLARVIRYPASALVVYSPVTERQVGQGMRVAELCAAALQYSDNTAANLLLELLGGP -AELTAFARRLGDPVFRLDRIEPDLNSALPDDPRDTSSAQAMALSLQRLALGDALDHAGRG -QLQTWLKGNTTGAKRIRAGVPAGWTVGDKTGSGDYGVANDVALLWPAGRAPWVLAVLSRS -AEAKAAWRDAALAEATRVVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0010321A1A ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFELARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AP36_KLEPN ---DVQQKLAELERQSGSRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAE----------------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium vallis TaxID=634290 RepID=A0A3S0Y7Q1_9RHIZ --dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEESLDRRVTYGKEKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTAPDAMLDTLGNLTLGSILTEASCD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE -ATVPAKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1I2WXL5_BACME -----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFTYASTSKALAVGALLQQKT ---IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDATLRYSDNTAMNLILKQIGGP -NGLEKALRDVGDNVTMPERFEPELNEVKPGETHDTSTPRALATSLQSFTLGDALPVEKRG -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPPKGDPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. F56 TaxID=1581850 RepID=UPI0009F41ECD ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEVCEAAIRYSDNTAGNLLFKKLNGP -KGFEEALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A5C5AVW4_9BACI --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia sp. SOS3 TaxID=1926494 RepID=A0A1L6I5G8_9BURK ---ALSTALRNIEAERGGRLGVAVLDSQTGKSA-GYRADERFPMCSTFKLLAAAAVLSRID -RGDDRLDRRIRFAASDVVVNSPVTQNRSAPEMTLAEICEAAMTYSDNTAGNLMLTSIGGP -KALTAYARSLGDTVTRLDRTEPELNEALPDDPRDTTSPAAMLSNLRDLVTGNALQRESRD -RLSGWLIGNKTGGSRLRAGLPREWRVGDKTGAGERGTTNDVAVVWPSEGRPLFISIYLTG -DRIDGKHQNATIASVGAALA--- ->[subseq from] KPC-5 protein n=7 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A0E3ZB52_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A179BY70_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFALARTD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCAAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=BLAC_BACAM -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKP ---IEKLNDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILTKR -FTKDAEYDNALIAEAAKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Phytobacter sp. SCO41 TaxID=1756993 RepID=UPI000D500151 ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPNGKPARIVVIYITE -TQATMDERNKKIADIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013C5DB7C ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFALARTD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCAAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRVIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. Bisph2 TaxID=1274400 RepID=UPI00057C08D0 ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SALTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE -TQATMDDRNKKIADIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 5 TaxID=1395608 RepID=A0A261TL50_9BORD -----QRLLARLEARDGGRLGVSVLDTGSGWAL-AHRSDERFPMCSTFKWVAAAAVLARVG -RGQDSLDRHIRYGATDLVPYSPVTKPQVAQGMTLGALCEAAVVWSDNTAANLMLSTLGGP -PGITAYARSQGDDQTRLDRIEPALNEAQPGDPRDTTTPQAMLRLLRRVLLEGGLEAPQRD -QLTAWLRGCRTGYTRLRAGLPADWIVGNKTGAGEHGTNNDVAVIWPPRGAPILVTAYLTN -SPASRDAQNALLAETARIVVH-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. FWC2 TaxID=69664 RepID=A0A2G5QSZ2_9CAUL ---ALNSRINELEQRSGGRLGVAVLDTHDGRRF-AWRGDERFRMCSTFKMPLAAAILRRVD -QGRERLDRRVTYGREVLMGNSPVVEKHLDRGMTIGELCAATITYSDNAAANLLLDALGAP -TDLTRFLRALGDQTTRCDRREPELNTGAPDDPRDTTTPTAIAETWKTLLTTDTLSAASRK -QLTAWVVANRTGGKRLRAGLPRSWTVGDKTGNNGQDQTNDIAVIWPPKRKPLFVAAFHDQ -GSADDDVRSAVLADVARAVVS-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8F0L4_BACCE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000DE58443 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNFKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q5GJ46_RAOOR -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARILRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] Beta-lactamase n=1 Tax=Bordetella sp. H567 TaxID=1697043 RepID=A0A1B2R9I9_9BORD ---AIDAEFARLERSHQRRLGLYALETGTGREI-AYRANERFAFCSTFKAVLAAATLAQDA -AQPGLLERRIIYTQHDLASYSPVTKERLGGGMTVAELCAAAVQYSDNTAANLLLHRLGGP -RALTAYARDVGNKSFRLDRYETALNTAIPGDERDTSTPADMGRMLEALVLGNALPAEART -RLKTWLLGNKTGDHRIRAAVPAGWQVADKTGTGDYGSANDFGIVWPPGRPPIVLAIYTGS -RDTHAKADESLIAEAARIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Geobacter lovleyi TaxID=313985 RepID=B3E6E6_GEOLS -----GEQISMIEKRHGGRLGIAALNTATGMRI-EYRSAERFAMCSTFKFILVAAVLKQVD -EKKISLDRGIPYTTADLLDWAPITKKHVSDGMTVERLCAAAIEYSDNTAANLLLDLLGGP -KAVTAYARSLGDSVTRLDRNEPSLNDNLPNDDRDTTSPSSMVETMNKVLSGHALSPSSRK -ILENYLLANTTGANRLRAGIPLDWRVGDKTGTGSNGAVNDIAVMWPPDRSPIFVAVYYSG -SPSPNSDREAVLAEVGKLIAIEf ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=X5JZE0_ENTCL ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D612_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013DC0172 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -KLIAWLVASATGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. AU40 TaxID=1637747 RepID=UPI000782672C ---ALNALLADIEKRFSARLGAFVHDTGSGRRW-ARRADERFPLCSTFKVVAAAGLLARVD -RGEADLSRRVVIAKSDLVTYSPVTEKQVGGEMTLAEICAAAITRSDNTAGNVLIDQLGGP -EGVTRFARSLGDETFRLDRRETDLNEATPGDPRDTTSPAAMTKTLHALLFEDHLKDVSRW -RLAEWMVANQTGGAKLRAGLPKSWHIGDKTGGGDHGTMNDIAVLWPPEGAPIVASLYLTE -TEASFDERNAAFAEIGNALA--- ->[subseq from] Beta-lactamase n=1 Tax=Neptuniibacter sp. Phe_28 TaxID=1795871 RepID=A0A136H9X2_9GAMM -hrSLIQTVERIAGEIEAQVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD -AGQESLDRRVSFSESDLVTYSPITEKHAGGQMSLADLCEAALTMSDNTAANLVLQALGGP -EKVTLFARVLGDDVTRLDRWETELNEAVPGDNRDTTTPNAMVKNLHNLLLGDVLSRKSRD -QLYDWLKRNQVADGLFRAAVPEGWIVADRTGAGGFGSRSITAIFWPPERQPIVVALYLTQ -TEASFSERNKAITEIGEAIV--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082C8FB ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGYARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia sp. TaxID=1926495 RepID=A0A522MU36_9BURK --kAIESELAAIERSVDGRLGVAILDLETGMRA-GHRAGERFPTCSTFKLMLAAQVLARVD -HGQERLDRRIVFGADRIERYAPVASKHIGEPMTVGELCDAIVTMSDNTAANLLLDTVNGP -AGLTAFMRQLGDTVTRLDRNEPSLNEAIPGDPRDTTTPLAMLGNVQTVLLGNALTAASRA -RLLAWGAGNRTGDARLRVGVPRAWRVADKTGTGERGTTNDIGLLWPEDGAPIVVTAYLTQ -TGAPARARDAAIADIARAISKH- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI000AF5648E ----FARAVQEVEASVGGRLGVALLDVATGRQD-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYRKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LALTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -RMLAWLVGNRTGDRRLRAGMPEGWRVGEKTGTGPRGTSNDIGLFWPPDRDAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. (strain B510) TaxID=137722 RepID=D3NZG0_AZOS1 ----LAAGMAALEERSGGRLGVAVLDTATGRLR-GWRGDERFPMCSTFKFLLAAAVLKSVD -QGKDRLDRRIPVTKADLLPYAPFSETRLTGTPTLAELCEAAVTLSDNTAANLLLPGVGDP -AGLTAFLRGIGDQTTRLDRNEPTLNSAIPGDPRDTTTPAAMVRGMERLLIGDVLRLDSRW -RLVDWLIANKTGDKRLRAGLPAGWRVGDKTGTGANGTANDIAIVWPDGRAPVLIASYLTQ -TAKGFKAQDSIHAEVARTVA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. juglandis TaxID=195709 RepID=A0A383T1L5_XANCJ ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00094ABD5A ---TVNHSFAKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDQRIVYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKMVLD-- ->[subseq from] Beta-lactamase TEM, Beta-lactamase PSE-4 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0003D6D8A2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009AC787D --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI2_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPASWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1T3P4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -ADDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YPT7_9BACL ---TLDQQFKQLEKDFDARLGVYALETGTGMTI-RYRDDERFAYASTFKALAVGAVLVQSP ---TEELDKRITYTSNDLISHSPITKEHVENGMTIRELCDAAVRYSDNTAANLLLKELGGP -EGFAKVLKQIGDDVTNPVRMELELNEATPGDIRDTSTPKALANSLQAFTLGEVLPADKRF -ILTNWMKENTTGDELIRAGAPTGWVVGDKTGAGSFGTRNDIAVVWPPDRAPIVIAILSSR -DTKDAKANDALIAKAAKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1A9PUF6_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVYPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH9_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTALLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0006526185 --dDIQRRLAALEKRTGGRLGVSVLDTETSISF-GYRGSGAFPMCSTFKALAAGFVLARAD -KGEESLDRRVTYGKDKLVDYSPISEKHAGADMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPEAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -AAAPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UXQ4_9BACI ----MDIKFAALEKQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDGVTKSERYETELNEAKPEDLRDTSTPKALATSLRAYTVGNALSSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthobacter sp. SG518 TaxID=2587119 RepID=UPI0014478E8D ----LEQAFAALEAESGGRLGVAVL-TATGASA-GYRADERFPLCSTFKALAAAAILARVD -AGTEQLERRIPVAQADILSYAPVAKQHVGGEMTIADLCAAAVLVSDNTAANLLLEALGGP -AALTAFVRTLGDTSTRLDRVEPELNEATPGDPRDTTTPAAMARDMLVLSAGTALSTASRE -RLNGWLIACTTGTAKLRAGLPADWRAGDKTGSGSHGTSNDVAVIWPPGRPPLVIASYLTQ -APGDDARRNGIHASVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B75F7 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RCI6_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. GV060 TaxID=2135696 RepID=A0A4R1V2B4_9BURK ---AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -GGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV -QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPILVAVYLTG -TAGDAARNNAAIANVGALVVE-- ->[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=Methylobacterium bullatum TaxID=570505 RepID=A0A679JZ07_9RHIZ --rDLADRFARIEEASGGRLGIGLLDTGSGAHA-AHRGDERFPLCSTFKVLAAGAALARVD -RGEDGLDRRLRYELREVVPYSPVSGPRAGGEMTIAELCEAAVTLSDNTAANLLLGTMGGP -AGLTGHIRRFGDATTRLDRTEPDLNEAAPGDPRDTTTPRAMAETLRRLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPPRRPPLVLTGYLTG -ARTSSEARSATIASVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Root219 TaxID=1736493 RepID=A0A0Q8T3N0_9BURK -----LADLKRIEASVGGRVGVAALDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD -QGHDKLDRRVTYAKKDLVTYSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP -PALTAYVRSLGDSITRLDRIEPELNEAKPGDPRDTTTPVAMVHCIQALALGQALSPASRE -KLQGWLLANKTGDKRLRARLPEGWKAGEKTGTASRSTSNDAGVFWPPARKPIVVSCYLTG -GEAPPEQRDAAMAEIGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RGT5_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Aureimonas ureilytica TaxID=401562 RepID=UPI00036ED242 -----DAVLAGIERRFSGRLGVYVIDTATERRW-GRRADERFPMCSTFKLMAAAGLLSRVD -AGTESLSRRVVIQPTDIVTYSPVTEHRVGGEMTLAEICEAALTQSDNTAGNVLIDALGGP -AGVTDFARSIDDDTFRLDRRETELNEARPGDPRDTTTPAAMAKSLAALVQEDALSDASRH -QLVEWLVANRTGDAKLRAGLPKTWRIGDKTGGGAFGTMNDVAVIWPEHRPPIVASIYLTE -TQASFDDRNAGFAEIGHALAD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RQ38_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A0A141RGV8_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIYYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4V1TL22_9BURK ----LRAQWAEIERSSGGRLGISLLDSGTGKRI-GLREDERFPLCSTFKFVLAAAVLQRVD -KGELTLAQRVKIRAADMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -AGLTAFLRGIGDARTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNVLKPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAAVKAVAQAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica (strain GUH-2) TaxID=1127134 RepID=H6R1V0_NOCCG ------PRFAELETTSGARLGVFAVDTGSGRTV-AHRADERFPMASTFKGLACGALLREHP -LSTGYFDQVIHYSAAELVEYSPVTETRVETGMTVRELCDAAITVSDNTAGNQLLKLLGGP -EGFTASLRSLGDATSRLDRWETDLNTAIPGDERDTTTPAALAADYRALVVGDVLGAPERD -QLKAWLVANTTGATRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK -SEQDAEPDNALLAEATRVVVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A02BC62 --qATHKEFSQLEKKFDARVGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQYS ---TENLNDVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1C3PVY4_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRALLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. WSM2230 TaxID=944435 RepID=UPI000401624A ---AIRARLTEIESQSGGRLGVSIIDTTSGLQA-GLHADERFPMCSTFKLLAAGAILARVD -RGEENLQRRIVYSQSELVPNSPATSMHTRERMSIAALCEAAITLSDNTAANLLLQTFGGP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELVMGERLTSASRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTE -TAGNTARSNAAIADVGALVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=J7I2U9_KLEPN ------EQIKLSESRLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTASLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00077A2976 ---TLKRQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVMD-- ->[subseq from] Mutant KPC family beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A6B7HYP7_ENTCL -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCY-GTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F51A251 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRSVVIYTTG -SQATMDERNRQIAGIG------- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520E9B3_9BURK ---NLVARLRQIETASGGRLGVCILNTADGQRF-GLRADERFPMCSTFKLLAAALVLQRVD -SQQDTLDRRIAIERSAIVPHSPLTEPQVGRSMTLGALCEATITQSDNAAANLMLASFGGP -AGLTAYVRSLGDPLTRLDRNEPGLNEAIAGDPRDTTTPAAMLGLMQQLVLGDALAPASRA -QLSDWLVANKTGDRKIRAGLPAGWKVGDKTGGGAFGTNNDVAIVWPPGRPPMLVTVYLTQ -TPATLAQRDATLAAVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHX7_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPANMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAVIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S7AH87_9XANT ----LRAQWAQIERGSGGRLGISLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVFQRVD -QGRLTLAQQVKIRAADMVSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRYVEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDACLRAGLPRGWKIGDKTGNNGTDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDATLKAVAAAVRDSf ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Nocardia asteroides TaxID=1824 RepID=BLAC_NOCAS ------PRFAELETTSGARLGVFAVDTGSGRTV-AHRADERFPMASTFKGLACGALLREHP -LSTGYFDQVIHYSAAELVEYSPVTETRVETGMTVRELCDAAITVSDNTAGNQLLKLLGGP -EGFTASLRSLGDATSRLDRWETDLNTAIPGDERDTTTPAALAADYRALVVGDVLGAPERD -QLKAWLVANTTGATRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK -SEQDAEPDNALLAEATRVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEF0512 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLVQRVEIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A1T2PIB0_BACCE --qATHKEFSQLEKKFDARLGVYAIDTDTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A386JTF3_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSPRLSVRSQR -QLLQWMVDDGVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. YR750 TaxID=1884384 RepID=A0A1H7Q5E8_9BURK ---SAEAQLAELERTSGSRLGVVGFNTGSGARV-QHRPHERFPLCSTFKLMLAAAVLERST -KDGSLLSRNLSYGKSDLIDHSPITEKHVATGMTVAAMCAATIQYSDNAAANLLLKELGGP -AAVTAFARGIGDQVFRLDRMEPELNTSIPGDPRDTTTPAAMSDSLQRLVLGDALGAAQRD -QLKTWLLGNTTNTDRFLSGVPAGWKVGDKTGAGSYGTTNDVGVLWPPAGAPIVLSVYLTF -PRKDAKGRNDVVASATRIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A0B4XWW8_9PROT ---RLLDAIHTVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAVLHKVD -RESEMLDRRITYRSDDLVTYSPITEKHVDSGMTIGELCEAALHLSDNTAANLVLDVLGGP -DVLTAYLREIGDDVTRLDRIEPDLNAATPGDARDTTTPNAMRATLTYLLFGDALSLESRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPERKPVIAAIYITQ -TSASMGERNAAIADLGQEIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCC9D6 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRTETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 78 TaxID=2135631 RepID=A0A2U0SU20_9BURK ---AAHTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYDKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003603C0C ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLILGSVLTEASSG -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium phaseoli TaxID=396 RepID=UPI0007EAE84D ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPISEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLLADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATTPAKDLNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF30303 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKKDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=A0A4V2TJC8_RAOOR -heATVKQVKAAERLLEARVGYVELDIASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEQLDRRVRYRQQDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLSGSVLSAASRQ -QLRNWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNRQIAEIGEMLVKHw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7UWB7_9BACL ---QIDQKFADLEKKFEARLGVYAIDTNTNQVV-AFRSDERFAFASTFKALVVGALLHQKS ---LDELDKVIKYTSSDLVTYSPITEKHVSTGMTLREISDAAIRYSDNTAGNLLFKELGGP -KGFEAALRKIGDQVTTSERNEPELNEAIPGDIRDTSTPKALATSLMAYTVGDVLTEDKQK -ILNDWLQRNTTGDKLIRAGLPKEWKVGDKTGAASYGTRNDIAVIWPPDKKPIVLAVLSSR -DTKDATYDNALIAEATKLVMD-- ->[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI00085379B7 ---AMDQKFAALENKFDVRLGVYAIDTETDVVV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYEPELNEAKPEDIRDTSTPKALATSLRAYTVGDVMSSDKQT -ILIEWLKGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL10I2N1 TaxID=1938796 RepID=A0A4R6F7M3_9BURK ---STEAQLATLEKSSGGRLGLFALNTATGEQT-RYRADERFPFCSTFKVILAGAILTRST -RVPGFMQQCVNYAQSELVHYSPVTAEHVGDGMTVAELCRAAIQYSDNTSANLLMKMLGGP -AAVTSFARSIGNSEFRLDRWETELNSVVPGDQRDTSTPAAMARSLQTLALGDTLPPPQRA -QLLDWLRGNKMGAKRIGAAVPADWQIGDKTGTGDYGTANDIAVLWPPAREPVVLAIYHTQ -LAADAKSRDDVIAVAARIVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Herminiimonas fonticola TaxID=303380 RepID=A0A4R6G6W2_9BURK ---AANNELEKLEASANGRLGVAAINTGNGMRV-QYRADERFPFCSTFKTIVAAAILQKSA -TDKGLLAKRIHYNKDELVKYAPITQKYIADGMTIAELCAATLQYSDNAAANFLMKELGGP -AAVTAYARSIGDDTFRLDRWEPELNSAIPCDERDTTTSAAMEKSLQQLMLGDALAVSQRV -QLVAWLKGNTTGGKRMLAGVPKDWIVGDKTGTGSYGTTNDAGVLWPVNGAPIVAVVYFTQ -NDKTAAPRDDVIAAATRIVIAAf ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D749FF8 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. populi TaxID=487823 RepID=A0A2S7B4U3_9XANT ----LRAQWAEIERSSGGRLGISLLDSGTGKRI-GLREDERFPLCSTFKFVLAAAVLQRVD -KGELTLAQRVKIRAADMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -AGLTAFLRGIGDARTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNLLKPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAAVKAVAQAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. C16 TaxID=2487400 RepID=A0A3S0Q2K0_9RHIZ --dNVEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVGKMIVE-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-36 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z5FPM1_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLERWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009B570D5 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRGSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RFN3_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL83_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTXGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAXXTTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase (Fragment) n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=G9G8D3_PSEAI -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPSDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. IBUN TaxID=1042326 RepID=UPI000413B245 --dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNVAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8FCR9_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLDYf ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEED68F ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase LEN-31 n=1 Tax=Klebsiella TaxID=570 RepID=UPI00032DDE2A ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTHLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] OFF7_DB12V4 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFAD -----AAKVKDAADQLGARVGYIELDLNSGKILaSFRSEERFPMMSTFKVLLAGAILSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP -KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKGw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3P4IN76_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVSGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus ATCC 4342 TaxID=526977 RepID=C2QT98_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=3 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2N7V2J1_XANCJ ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE8_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHCSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0011E934EE -----AHKFMQLEKKFDARLGVYAIDTGTNRTV-VYRPDERFAYSSTFKALAAGAVLQQNS ---IEELDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLEEIGGP -DGFENALRQIGDHVTEADRFETDLNSAIPGDIRDTSTARALAINLKAFTVDDVLPIDKRT -ILTDWMKGNTTGDELIRASVPKGWEAGDKTGAGGYGTRNDIAIVWPPNRDPIIITILSSR -DTENATYHNELIAKAAKVVLNSf ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora globbae TaxID=1894969 RepID=A0A420F021_9ACTN -------DFGRLEARFDARLGVYAVDTGTGRTI-EHRADERFGYASTFKALAAGALLAATS ---TTELDRVVRYTEADLVTHSPVTERHVKTGMTLRELGDAAVRYSDNTAANLLLRRLGGP -AGFERALRELGDRVTDPERFETDLNEATPGDRRDTSTPRALASDLRAYILGDALAPEDRA -VLTGWLKGNTTGDTLIRAGVPAGWQVGDKTGSGGYGTRNDIAVVWPPDGAPIVLAILSSR -EEKDASSDDTLIAEAAKATIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B451C70 ---TVNHSFAKLEKEFEAKLGIYALDTDTNQTV-KYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGDWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDF554D ---QFRPALEAIETRIQARLGAFVLDTETGTTL-GYRADERFPMCSTFKAIAAAAVLSRVD -AGKEDLSRRLHWKKADLIAHSPVTEKHVEAGLTLAELCHAATTVSDNTAANLLLEAIGGP -AGFTAFVRSVGDPVTRIDRMEPALNSAKPGDTRDTTSPSAMAALLKSLVLDDALSPASRD -QLGQWMIANTTGGSKLRAGLPRGFIVGDRTGAGANGTNNVVAVIWPPERKPLVATVFITE -TRTPRPETDPAMAEIGRL----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF1_9BACT ---ETLVKVRDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGPRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102F5E76 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFALARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDATTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. 3376 TaxID=2663862 RepID=UPI00142F4D06 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -PGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase LEN-55 n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000BA1327B ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D618_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2BD875 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] OFF7_DB08V4 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFBE -------QVAAAADQLGARVGYIELDLNSGKILeSFRSEERFPMMSTFKVLLAGAILSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP -KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKNw ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus mucilaginosus TaxID=61624 RepID=I0BH80_9BACL ---SAKQPFARLESEYKARLGVYAVDTGTGRTI-EFRPDERFAYASTFKALACGAVLKAKP ---LEGLEDRVTYTSGELVTYSPVTEKHVSTGMTLRELCDAAIRYSDNTAGNLLLKQLGGP -KGFEAALKEAGDAVTKAERYETELNEAVPGDDRDTSTPRALASSLRAFTLGDALSADKRD -VLADWLRRNTTGGELIRAAVPEGWVVGDKTGAGSYGTRNDIAVIWPPDGPPIVMAVLSSR -DTKDAAYDNALIAKAAKAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter farmeri TaxID=67824 RepID=A0A223JSU2_9ENTR ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRADERFAMCSTSKTIVVAAVLKQSE -TQHDILQQKMTIKKTDLTNWNPVTEKQVNKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -GNVTAFARSIGDATFRLDRTEPELNTAIPGDERDTTSPLAMAKSLHKLTLGNALADMQRA -QLVAWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEFCD86 ---AMYKNFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEVTYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH6_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGVTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141BF4B5 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQLASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-51 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A650DI28_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARNTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGHGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKNSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas azotifigens TaxID=291995 RepID=UPI0004265009 ---AFERRLARIEAEVCGRLGVALLDTDDGLRA-GRRQDERFPLCSTFKFLAAAALLARQD -RGELSLAQRVVFGEADLVEYSPVTGARTGGEMTLAEICEAAVTRSDNTAGNLMLAHLGGP -QGLTAFARGLGDRQTRLDRLETELNEALPGDPRDTTTPAAMLADMRELLLGTHLSPASRE -QLQAWLIANRTGDARLRAGVPKDWRAGDKTGSGERGTANDIAIFWPPTRGPVLVAVYLTG -SAADMDRRNAAIVQVGTALAE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000859D685 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMGDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1C4DFF5_BACCE ---TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A242ZFI8_9BACI ---TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. THAF187b TaxID=2587864 RepID=A0A5P9BXV5_9RHOB ----LEKTVAGAESRLSARIGVAVLDTETGKTW-TYRADERFPLNSTFKAFLCAALLEKGE -QGEVQLERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -EGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARA -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter sp. 10-1 TaxID=559104 RepID=A0A267RL20_9ENTR -hdATVNKVKAAESQLKARVGYAELDLASGQLLaSYRPDERFPMMSTFKVPLCAAVLARVD -AGEEKLDRRVRYRQQDLVEYSPVTEKHLADGMTVAELCAAAITLSDNSAANLLLASVGGP -EGLTAFLRRSGDQTSRLDRLETELNEALPGDARDTTTPQAMAKTLRNLLTGSVLSASSRQ -QLRRWMVDDKVAGPLLRSALPNGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNREIAGIGETLIKHw ->[subseq from] Beta-lactamase n=3 Tax=Xanthomonas arboricola pv. pruni TaxID=69929 RepID=W4SHG2_9XANT ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIHNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B5A120_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI000C06EE12 --qTLKSQFETLESKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATQFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPVDWIVADKTGSGDYGTTNDIAIIWPKNQAPIILTAYFTQ -NDKDAVARKDVLASAAKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0XTV2_BACCE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNRKPIVLAILSNH -DKEDAKSDDKLIAEATQIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchialis TaxID=463025 RepID=UPI0009F6432D -------EYAALEQSHRRRLGVYALDTGSGQEV-AYRAGERFAFCSTFKAILAAAVLAQDA -GKPGLLRQRVAYTKSDLVSYSPVTGEHAGAGMTIAELCAAAVQYSDNTAANLLLHRLGGP -AALTAFARQAGNPSFRMDRYETALNTAIPGDERDTSTPADMAGLLRALVLGDALPAPARA -QLKTWLLGNKTGAHRIRAAVPGGWAVGDKTGTGDYGSANDVGIIWPPSRPPIVMAIYTGS -RDKRAKADEGLIAEAARIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus glycinifermentans TaxID=1664069 RepID=UPI000653CAC5 -----SNQFSRLEDQYDARLGVFALDTGTNKTV-TYRADERFAYASTHKALAVGALLKQTS ---IADLNQRITYTRDDLVNYNPITEKHVDTGMTLKELCDASIRYSDNTAGNLILKQIGGP -SGFKQSLREIGDNVTNPERIEPDLNEVKPGETHDTSTPKALAKSLQAFTVGDALPKEKRE -MLVDWLKRNTTGDALIRVGVPKGWEVADKTGAGSYGTRNDIAVIWPSKGDPIVLAVLSSR -DKKDADYNDKLIAEAAKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bk TaxID=1938441 RepID=UPI000B48E883 ---TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVGDLCKAAITLSDNTAANLLLASFGGP -AALTAFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE -TAGDAVRCNAAIASVGALVAQ-- ->[subseq from] Class A beta-lactamase TEL-1 n=2 Tax=unclassified Citrobacter TaxID=2644389 RepID=A0A650EM83_9ENTR ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRGDERFAMCSTSKTIVVAAVLKQSE -TQRDILQQKMAINKADLTNWNPVTEKYVDKEMTLAELSAAALQYSDNTAMNKLLEHLGGT -GNVTAFARSIGDTTFRLDRTEPELNTAIPSDERDTTSPLAMAKSLHKLTLGDALAGMQRA -QLVAWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000271AE47 ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLERKIVYSKDVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRKEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Legionella taurinensis TaxID=70611 RepID=A0A3A5L4J6_9GAMM ---SLQQKLAALEASAGGRLGIAAINQANGMTI-QYHARQAFPLCSTSKAMSVAALLSQNM -RNKTLLQEKIHYSKQDLVVHSPETEKHLADGMTLAELCEATITQSDNAALNLILKKIGGP -GAVTAFARSIGDKQFRLDRFEPDLNTAIPGDPRDTTTPKAMALSLQKLTTD-TLAAPERQ -LLITWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTSNDIGVIWPPHCQPVTLAVYFTQ -PKVDATPNNDVIAAATRIVISAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000374CAD5 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSETFPMCSTFKALAAAFVLARAD -KGEENIDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLKEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus var. anthracis (strain CI) TaxID=637380 RepID=D8GY68_BACAI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLVEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Haliea sp. TaxID=1932666 RepID=A0A519HD37_9GAMM ---AAQARLAALETASGGRLGVFALNTADGSVI-SHRGDERFPLCSTFKAIAAAAILERNM -REPGLLSQRIKYTQVELVTYSPITEKHLADGMTVAELCAAAIQYSDNTAGNMLIKVLGGP -PAVTAFTRSIGDNAFRLDRWETELNTAIPGDARDTTTPAAMAATLQKLVLGDTLAPPQRE -QLQAWLRGNTTGATRIRAGVPAGWIVGDKTGGGDYGANNDVAVLWPPGKPPIVLALYMTQ ------------------------ ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000F297080 -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRAD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIATIGETLVRHw ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1D9N9L5_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQ-IAGIGAALIEHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D75085B ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D617_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5C2D365_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSTIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGAANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000C85B9E2 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -MGELTLAQRVKIHASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDTHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3R967_9BURK ---AAHDALRQLESDMGGRLGVAAFDGRPGSLAlLHRADERFPMCSTFKVIAAAGVLARSA -REPGLLNQRTRYTREDLVTYSPVTEKHVADGMTVAELCAAALQYSDNTAGNLLIRLLDGP -AGVTRYARSIGDEGFRLDRWETELNTALPGDPRDSTTPASMARSLQRLLLQNGLPAAQRA -QLEQWMRGNTTGATRIQAGVPAGWAVADKTGAGAWGTTNDVGVVWRADGSPLVLAIYLAQ -PRADAPMRNDTVAAAARIAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus hauseri ZMd44 TaxID=1312367 RepID=V6MJL4_PROHU --nTIEEQLSTLEKYGKGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNITIKKSDLVVYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTALHGDPRDTTSPIAMAKSLQALTLGDALGLSQRQ -QLVTWLQGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKAAEIVTKPf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0004C542C7 ---EVSRRLQALESEHGARLGVFARNLDTGETV-VRRADERFPMCSLFKPVAAAAILRDHD -RNGAFLARRIRYSETDLVTHSPITKDHVAEGMTVGELCDAAIRFSDNTAANLLLRELGGP -RAVTRFCRSVGDRTTRLDRWEPELNTAEPWRVEDTTSPRAIARTYTRITIGDALSPADRE -RLTGWMLANTTSGERFRAGLPAAWDLADKTGGGDYGTNNDAGVAWTPDRTPIVLAVLTTK -PAPDAAPDNALIAETAELLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000C8306A1 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTSTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1H2RD10_LYSEN ---ALRARLAELEKRSGGRLGVSALDTADGRRF-DVRGDERFAMCSTFKFLLAAAVLRKAD -LGELDMQQRLAVPKSALISHSPITTPIAEAGASLAQLCEATMTISDNAAANLLLPLVGNP -AGLTRFLRGIGDKVTRLDRNEPELNTALPGDPRDTTSPNAMLASMRTLLLGDALSAASRR -QLTDWLIANQTGDKRLRAGLPKSWRIGDKTGSGN-GTTNDIAIIWPQGRKPVFITTYLTQ -AQGEDDARSAILADAARALAQHw ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia nodosa TaxID=392320 RepID=UPI0008414357 ---AVEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMHERFPMCSTFKVLLASAVLTRKD -HGKEDLARKIVYSLAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP -PAITAFARSIGDPVTRLDRNETTLNEAIPGDPRDTTMPAAMVANLRELLLGERLSAASRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIVWPTERAPILVTTYLTG -ATASSAQRDAAIAQVGVWA---- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AEAE2A --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLVEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWMKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. EL159 TaxID=1566270 RepID=A0A1G4XX81_9BURK ---SAEAQLAALESASGGRLGVVAFNTASGARV-QHRAHERFPFCSTFKLMLSAAILERSA -KDASLFTRRVNYSKGDLVSYSPVTEKNLATGMTVAELCAATAQYSDNGAANLLLKILGGP -PALTAFARSIGDQTFRLDRWETELNTAIPGDLRDTTTPAAMADSVQRLVLGDALGSAQRE -QLRTWLLGNTTSKERFLAGVPADWKVGDKTGSGDYGTTNDIGVLWPPAGAPLVVTVYLTF -PQKDAKGRNDVVASATRIVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. 35 TaxID=2035210 RepID=UPI000C181BE8 ---AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYDKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2F9K3_BACCE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPKRFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPVVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Gibbsiella quercinecans TaxID=929813 RepID=A0A250B928_9ENTR -hqATLDKVKEAEGLLNARVGYAELDLTSGNLLeSYRPQEHFPMMSTFKVLLCGAVLSRVD -SGHEQLDRRIQYHQRDLVEHSPVTEQHLSDGMTVAELCRAAITMSDNTAANLLLSTIGGP -RELTAFLRKTGDKVTRLDRWEPELNEALPGDERDTTTPKVMAQTLRQLLTGKTLTATSQK -QLMDWMEADKVAGPLLRSVLPAGWFIADKTGAGERGSRGIVAALGPDGKPSRIVVIYLTG -TQATMDERNKQIAEIGELLIKYw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sullae TaxID=50338 RepID=A0A4R3QLS6_RHISU --dDIERRLAELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYDESKLVSYSPETEKHVGGEMSVAELCKAAITLSDNTAGNLLLESFGGP -EALTKWLRSIGDRSTRLDRWETALNEGKKDDPRDTTTPDAMLDTLGNVALGSVLSEPSRN -TLIGWMMANTTGGARLRAGLPGSWKVGDKTGTGNNGTAADIAITWPKGRGPILVTTYIAE -ATAPVKELNPVFAEVAKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia pekkanenii TaxID=1288385 RepID=A0A0T9NHX1_9GAMM ---SLDNQLAELEQTSNGRLGIALINTANGKKV-QYRGGQRFPFCSTFKLMLAATVLGHSQ -FQPNLLNKHLRYHENDLLSYAPITRKNLAQGMTISQLCAATLQYSDNTAANLLIKELGGL -GSVNQFARSIGDQTFRLDRWEPDLNSALPNDPRDTTTPVAMAASLQKLVLGDALAAPQRE -QLARWLKGNTTGGETIRAGAPADWVVGDKTGSGDYGTTNDVAVLWPTQGAPLVLVIYFTQ -RNKEATSRRDVLASATKIVLSH- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 17-SMS-01 TaxID=2039284 RepID=A0A2G6Q9Z8_9BACI --qATHKEFSQLEKKFDARLGVYAIDTSTNQTI-SYRPNERFAFASTYKALVAGVLLQQNS ---TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVQKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Glaciimonas immobilis TaxID=728004 RepID=UPI0014399D3D ----AKNKIEKIERDFDGRLGVSVRDTATGRQL-GHRADERFPFCSTFKVIAASAILTKSV -QVPGLMERVIRFRQSDLVTYSPVTEKHVDTGMTVADLCAAGIQYSDNTAANLMIKLIGGP -AAVSAYARTIGDTAFRLDRWETALNTAIPGDLRDTSTPFAMCQSLNRLLLGDAMSFAHRE -QLRSWLSGNTTGAQRIKAGIPGDWLIGDKTGSGDYGTANDLAVLWPPKRAPVIVAIYTTQ -HAKEIASRSDIIASATRVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI00056A589C --dEINRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRVVYDQDKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP -PELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLALGSALSEPSRD -KLTEWMVANTTGGARLRAGLPGAWRIGDKTGTGNNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPLSEINPVFAEVGRIVAD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A0J7DJ89_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5NL20_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase KPC-15 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=M1NGU8_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVRWSPISEKYLTTGMTVLELSAAAVQYSDNAAANLLLKELGGP -AKLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D10A78E ---AMDQKFAALETKFDARLGVYAIDTETDVVV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATNLRAYTVGDVLSSDKQT -ILIEWLKGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDTLIAEATKVAVE-- ->[subseq from] Beta-lactamase n=3 Tax=Klebsiella TaxID=570 RepID=Q939H3_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A1L3ZAF3_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSESFPMCSTFKALAAAFVLARAD -KGEENLDRPVSYGEDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPVDWTVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0012989DAC --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A broad-spectrum beta-lactamase OKP-B-22 n=1 Tax=Klebsiella TaxID=570 RepID=UPI000F01C784 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMTERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. glycines TaxID=473421 RepID=A0A517GRB7_XANCG ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMVYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDATLKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella bronchiseptica TaxID=518 RepID=UPI00028A58B2 ---QAQRQLALLEQRHGVRLGVQVHDRDSDRAF-SHRADERFPMCSTFKLLAAGAVLARAD -RGDDSLRRLIRYGAADIVAYSPVTGPRQAEGMTLEQLCEAAVTRSDNTAGNLLLSTLGGP -PGLTAYARGLGDRMTRLDRIETALNEARPGDPRDTTTPAAMAGNLQRLLLGDALQPASRQ -RLAGWLLASQTGDTRLRAGLPAGWRIGDKTGVGGHGTNNDIGVIWPRDGAPALISAYLTQ -SSASREAQNAVLAEVGRIAAH-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007E8FA21 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVXLCGAVLARXD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATXGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLXSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus hwajinpoensis TaxID=208199 RepID=UPI0013705C2B ----TGRKFMQLEKKFDARLGVFAIDTSTNRTV-VYRPDERFAYTSTYKAVAAGLVLQQNS ---IDKLDEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLQKLGGP -NGFEKALRQIGDNVTEADRFETDLNSAIPGDIRDTSTARALATNLKAFTVDDVLPNGKRA -ILTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSTR -DTKNATYNNDLIAKTAKVALNAf ->[subseq from] Beta-lactamase n=1 Tax=Rhodovastum atsumiense TaxID=504468 RepID=A0A5M6IQK2_9PROT -----EARLAALEREHGGRLGVAVLDVATGHRI-AYRAEERFPLCSTFKVLAAALVLARVD -RGKERLDRRVVFSREDIRPWSPVTEKHPGAPMTLAELCEAAVTLSDNTAGNLLLGSFGGP -AGLTGFARALGDDVTRLDRFETALNEGTPGDPRDTTTPAAMLGNMRRIMVGDALSESSRT -QLAGWLLGSRTGGRRLRAGFPPDWRVGDKTGGNGTGVANDIAIAWPPGGGALLVAAYYAE -SPGPEERRNAVLAEVGRIAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8C2AB ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPVVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=A0A4R0A414_9RHIZ ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLGRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEE1C1A ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAASVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00020599E6 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKP ---IEKLNDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDAEYDNALIAEAAKVALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSAFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Class A beta-lactamase n=1 Tax=Rahnella sp. AA TaxID=2057180 RepID=A0A2N0W036_9GAMM ---TVQQQLAALEKDSGGRLGVMLINTADNSQI-AYRADERFAMCSTSKFMAASAILKQSE -TQKDLLAQPVSIKKSDLVNYNPIAEKHVNGTMTLGELAAAALQYSDNVGMNKLIEHLGGP -QKVTEYARTLGDDTFRLDRTEPTLNTAIPGDERDTSTPRAMALSLQKNALGDGLARPQQA -QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PQQDAKSRRDVLSSAAKIVTQGy ->[subseq from] Beta-lactamase n=1 Tax=Pragia sp. CF-458 TaxID=2498113 RepID=A0A411WK11_9GAMM ---TIQQSLADLEKSSGGRLGVVLINTADNSQI-VYRGDERFPMCSTSKMMVVAGVLKQSE -SQKGLLDQQVDIKKKDLVSHSPIAEKRLNNKMSLAELSAATLQYSDNAAMNKLIEQLGGT -KKATAFARSIGDKTFRLDRTEPTLNTAIPGDKRDTTTPLAMALSLQKLTLGDALAAPQRD -QLVEWLKGNTTGAASIRAGLPTEWVVGDKTGSGSYGTTNDIAVIWPKDKAPLILVTYFTQ -NEKEAKSRREVLASAAKIITQ-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000BBAD118 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGTNALVPWSPISEKYLPTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELPTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium acidisoli TaxID=1538158 RepID=A0A0N1DNN0_9RHIZ --dNIQKRLAALEKRTGGRFGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGFVLARAD -RGEESLDRRVTYGKDKLVDYSPLSEKHADADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASAD -RLVAWLVASTTGSERLRAGLPAGWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF701F9 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNY ---TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=A0A5C8IWN5_BACAM -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKQKP ---IEKLNDVIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDAEYDNALIAEAAKVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus paranthracis TaxID=2026186 RepID=A0A4P9F0E4_9BACI --qATHKEFSQLEKKFDARLGVYAINTGTKQTI-AYRPNERFAFASTYKAFAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATDLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RDQ7_9BACT -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTPLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HBCD-sjtu TaxID=2053832 RepID=A0A2K9A302_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTKQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TMKLDKVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDWVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIVAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Aureimonas sp. AU20 TaxID=1349819 RepID=A0A0S2EK77_9RHIZ ---ALNALLADIEKRFSARLGAFVHDTGSGRRW-ARRADERFPLCSTFKVVAAGGLLAQVD -RGEADLSRRVVIAKSDLVTYSPVTEKQVGGEMTLAEICAAAITRSDNTAGNVLIDQLGGP -EGVTRFARSLGDETFRLDRRETDLNEATPGDPRDTTSPAAMTKTLHALLFEDHLKDVSRW -RLAEWMVANQTGGAKLRAGLPKSWHIGDKTGGGDHGTMNDIAVLWPPEGAPIVASLYLTE -TEASFDERNAAFAEIGNALA--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E58AD9E ---ETLVKVKDAEDQLGARVGYIELISTAVRSFeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B4BF51D --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAKAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. (strain CCGE1003) TaxID=640512 RepID=E1TJ23_BURSG ---AIRARLVEIEAQSGGRLGVSIVDTTSGLHA-GLRADERFPMCSTFKLLAAGAVLARVD -RGEENLQRRIVYSQSELVPNSPATSRHTRERMSIAELCKAAITLSDNTAANLLLQSFGGP -AALTAFARSLGDGMTRLDRNEPTLNEAAPGDPRDTTTPNAMLGNLRALVMGEQLSSTSRV -QLLAWLAANETGGARIRARLPKDWGVGDKTGTGGHGTANDVAILWPPGRGPILVAVYLTG -TAGTAARCNAAIADVGALVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1L2K8_BACCE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPEHFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces tubercidicus TaxID=47759 RepID=A0A640UR18_9ACTN ----SAREFKALERKFDARLGVYALNTGTGREV-SYNADQRFAHASTFKAMAAGAVLRKYS ---LHGMDKVIKYSRDDLVPYSPVTEKHVDTGMTLRELCDAAVRYSDNTAANLLFDALGGP -KGLDSVLEELGDHTTRMVRREPELNEWAPNDTRDTTTPRAFAKDLRTFVLGDVLPRPERA -QLTKWLQTNTTGATLIKAGVPKNWVVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR -TEKDGERNDALVAQAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q5S1P8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSVANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TLASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BFB8C17 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKRPIVLAILSNH -EKEDAKYDDMLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7CWQ7_BACCE ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKRPIVLAILSNH -EKEDAKYDDMLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD71813 ---DVEARLAELEKRTGGRLGVSVLDTATNISF-GCREDERFAMCSSFKALAAGFILARVD -QGAETLDRRIVVAQKDIIAHSPVTEKHLGGEMTIADLCAATMTTSDNAAANLLLESFGGP -SALTAWLRMIGDETTRLDRNEPTLNEAKKGDPRDTTTPAAMLETLGNLAFGPALTADSRK -RLIEWMVANTTGDKRIRAGLPKGWKVGDKTGTNATGSASDIAIVWPEGRAPLLIAVYIAE -ATAPLSVLNTVFADVGRMAAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC5_9BACT -----LVKANDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRFVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola subsp. tropicalensis TaxID=2489014 RepID=A0A455LP02_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGNAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D17DC58 ---ALARAVQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGQSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGMPGGP -LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X1B2_9BACT -----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFTYASTSKALAVGALLQQKT ---IEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP -NGLEKALRDVGDNATMPEQFEPELNEVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGEPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D626_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL21I4N1 TaxID=1938801 RepID=A0A2S8RZY6_9BURK ---TIRRRLARIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLAAGAVLTRVD -RGQESLARRIVFSQRDVVPNSPATSRHTRERMSIADLCKAAITLSDNTAANLLLSTFGGP -AGLTAFARDLGDGITRLDRIEPTLNEAIPGDPRDTSTPNAMLGNLRELVLGEHLSASSRA -QLLAWLVANETGGARIRAKLPQDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVAVYLTG -TDGDAARCNAAIAQVGALVVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio sp. TaxID=885 RepID=A0A3D4GKK6_9DELT --kALQAQLAALSREAGGRLGVAFLDPATGRRF-AFRGGERFPFCSTFKFVLAAAVLRKSQ -DEPGLLAQPEAYGQGDLLAWAPATRKALEQGMTVGELCAAAITVSDNTAANLLLDRIGGP -KALTAFARGLGDTAFRLDRREPELNTAVPGDARDTTTPLAMARTMAKLVLGDALAAPQRR -QLADWLKGNTTGGESIRAGVPAGWTVGDKTGGGAYGTTNDVAVLWPPQGGPVVLAVYFTQ -PRKDALARKDVLAAATRLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=UPI0012902E9C ---AVEQEFNRLQTQHDARLGIYAVDTGSGKSI-AFRADERFAYASTFKALAAAAVLDTTT ---PQQLDEVVRYTAEDMLANSPITEQHLDTGMTLRDLCDAAVRYSDNTAGNLLLRHVGGP -AGLDAALTAIGDDVTSVDRYEPDLNSAIPGDVRDTSTPRAMAGNLRQYVLGDALAEDDRA -VLTDWLRRNTTGATLIRAGVPGDWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSR -DEPRAKRADALLADAARVAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A3N2RKG9_LYSEN ---ALRAQLRELERRSGGRLGVSALDTGDGRRF-DVRGDERFAMCSTFKFLLSAAVLHKVD -RGDLDLQQRIAVTKSALVPHAPFTGPIAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP -AGLTRFLRGIGDPTTRLDRNEPELNSAAPGDPRDTTSPNAMLASMRTLLLGDALSAASRK -QLADWLIANKTGDKRLRAGLPKDWRIGDKTGSGNT-STNDIAIVWPDGRKPVLMTVYLTQ -AQGEDEQRSVILAETARALAAHw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella sp. H-Nf2 TaxID=2054599 RepID=UPI000C288D5E ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATIGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQH -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAER-------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BF49C3F --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IHTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Root217 TaxID=1736492 RepID=A0A0Q8SBG3_9BURK -----LADLKRIEASVGGRVGVAALDTHTGRQI-AHRGGERFPMASTFKLLLAAQTLRRVD -QGHDKLDRRVTYTKKDLVTYSPVTEPHADGALTVEELCAGTMTLSDNTAANLLLASNGGP -PALTAYVRSLGDSITRLDRNEPSLNEAKPGDPRDTTTSVAMVHCIQALALGQALSPASRE -KLQGWLLGNKTGDKRLRARLPEGWKAGEKTGTASRGTSNDAGVFWPPARKPIVVSCYLTG -GEAPPEQRDAAMAEIGALVAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. AFS094611 TaxID=2033516 RepID=A0A2A7DZS2_9BACI -----YKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKSFTVGNALPDHKRY -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKDAPYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=J0VK68_RHILT --dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD -RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKELNPVFAEVGKMIVE-- ->[subseq from] Beta-lactamase 1 n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=A0A5P9PXT8_9PSEU ---AVEQEFNRLQTQHDARLGIYAVDTGSGKSI-AFRADERFAYASTFKALAAAAVLDTTT ---PQQLDEVVRYTAEDMLANSPITEQHLDTGMTLRDLCDAAVRYSDNTAGNLLLRHVGGP -AGLDAALTAIGDDVTSVDRYEPDLNSAIPGDVRDTSTPRAMAGNLRQYVLGDALAEDDRA -VLTDWLRRNTTGATLIRAGVPGDWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSR -DEPRAKRADALLADAARVAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7ISN1_BACCE ---TVNHSFSKLEKEFNAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFTLGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATQIVLD-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D744E27 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLLRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium etli TaxID=29449 RepID=UPI000A28FA5F ---NVEHRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEENLERRVTYGREKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATASVKDLNSIFAEVGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella electrica TaxID=1259973 RepID=A0A514ER89_9ENTR -heATVATVKHAESQLQGRVGYAELDLASGQLLaGYRPDERFPMMSTFKVLLCGAVLSRVD -AGEEQLDRRIHYRQQDLVEYSPVTEKHLTAGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTAFLRHSGDQTSRLDRWETELNEARPGDVRDTTTAQAMARTLRNLLIGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAGRIVVIYLTG -TPASMDERNKQIAAIGKTLVAHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2W5A7_BACCE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATQIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MBB9_9BACL ---AMDQKFAALENKFDARLGVYAIDTETDLAV-AYHEDERFAFASTYKALAAAAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDGVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGNVLSSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7X9Z6_9BACL ---AMDQKFAALENKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDGVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGNVLPSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSKR -DKQDAAYDDALIAEATKIAVD-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=Q6R5M7_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2D1F9C ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A0E3UEI1_9XANT ----LRAQWAEIERRSGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQLASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC-13 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=F2X6V8_ENTCL -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLGTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase KPC-11 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D7RIC6_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVLWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0007CC300D ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDMRDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Allonocardiopsis opalescens TaxID=1144618 RepID=A0A2T0QEZ7_9ACTN ----FEPQFQQLESEYDALLGVYAVDTGTERTI-SYNADQRFAYASTFKALAVGAVLQQNT ---IEELEEVITYTSDDLVNHTPITEQHVDTGMTLRELCDAAIRYSDNTAANMLFEELGGP -SGLDAALEGIGDDVTHVDRIEPHLSDYEPGDIRDTSTPQAMATSLRAYTLGEVLPPDERA -ILVDMLRGNTTGDELIRAGVPADWEVGDKTGSGSYGTRNDIAILWPPDREPIVVAIMTSN -DDPDAEYDNALIADAATVIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A4Q8XWD1_RHILE ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGDENLDRRVSYGKDKLVDYSPISEKHAGTDMILAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=Q63B80_BACCZ --qATHKEFSQLEKKFDAQLGVYAIDTGSNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRKMGDRITMSDRLETELNEAIPGDIRDTSTAKAVAMNLKAFTAGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas abietaniphila TaxID=89065 RepID=A0A1G7SCN8_9PSED ---SIEQGLAELERRHGGRLGVAILDTGSQRLI-AHRGDERFAMCSTFKALAAAYVLARVD -RKEEDLSRVIVYGKDQLVPYSPTTEKHTGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP -PALTAWLRSTGDQVTRLDRREPDLNENRAGDPQDTTTPIAMLQSLRTLILGDVLSGASRD -QLIAWLVSNTTGDKKLRAGLPKAWRVGDKTGSNAKNASNDVAIVWPTGRPPLVVSVYYDH -PRLGDDQVNTVIADVARLIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium oligotrophicum S58 TaxID=1245469 RepID=M4Z7N3_9BRAD ---DLQATIAGIEADSGGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILGKVD -VGTEQLARRIPIAQGDILSYAPVTKAYVGTSLSVGELCDAAVTLSDNTAANLLLATLGGP -AGLTRAIRGFGDAVTRLDRIEPELNESVPGDPRDTTTPAAMAQTLAKLTTGNALLPASRD -QLTAWLIACKTGGARLRAGLPAEWRVGDKTGTGEHGSANDVAVIWPSGRAPVIVTSYLTE -TKAGDDRRNAVHAAVGRAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001030EC10 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGDENLDRRVNYGKDKLVDYSPISEKHAGTDMILAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASCD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=A0A285RSF4_9PROT --dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTVKLLACAAILHKVD -LGTETLDRRIIYGVEDLVTYSPTTEKHVDGGMTIGELCEATLHLSDNTAANLILDALGGP -DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces thermoviolaceus TaxID=1952 RepID=UPI00143A7602 --qEAADRLGALEDRYGARLGVHARNVRTGQVV-AHRADEVFAMCSVFKTFAAAAVLADQD --RCTPLDRLVAYPPADLLPNSPRTEEHVDTGMTVDDLCAAAIRYSDNTAGNLLLRQIGGP -AGLTRFFRSLGDRVSRLDRWEPDLNTAVPGDPRDTTTPQALGRLLERLTLGDALAAADRA -RLVDWMKGNTTGDGRIRAGVPEGWTVADKTGTGSYASAHDVGVAWTTRSTPVVLVVLSSK -ETADAPVDEALLADAARVVAD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C796C80 ------EQIKLSESQLSGRVGMIEMGLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B6E133_KLEPN ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000A764367 --qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVIMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus vulgaris TaxID=585 RepID=UPI0013D55BB1 ---TIEEQLSTLEKNSQGRLGVALINTKDNSQI-TYRGDERFAMASTSKVMAVAAVLKESE -KQAGLLDKHMTIKKTDLVTYSPITEKHLATGMTLAQLSAATLQYSDNTAMNKILDYLGGP -SKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPLTMATSLQLLTLGDALGQYQRQ -QLITWLKGNTTGDQSIKAGLPNNWVVGDKTGSGDYGTTNDIAIIWPENQAPLILVVYFTQ -QKQNAKPRKDIIVKATEIVTKEy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea TaxID=53335 RepID=UPI0006DD4147 ---TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPFTQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=L0LIB6_RHITR ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAIKEDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEIGKIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. 7Q-K02 TaxID=2571747 RepID=UPI001315EDDF ---ALEKPLAAIEAQVGGRLGVAMLDTASGHVG-GWRLHERFPMCSTFKVLLASAVLTRKD -HGKEDLARKVVYTHAQVVSYSPVSGPRAGGEMTVAELCEAALTRSDNTAANLLLESIGGP -PAITAFARSLGDPVTRLDRNETTLNEAIPGDPRDTTMPAAMVANLRELLLGERLSSASRE -QLIAWLVANKTGDARLRAGLPKDWRLGDKTGTGDRGTANDVAIIWPTGRAPVLVTTYLTG -ATASSAQRDAAIAQVGVLLAHRy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE2B5A5 --dEINRRMDALEKAIGGRIGVSAIDTETNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMLDTLGNLTLGSALSEPSRD -KLVAWMVANTTGGARLRAGLPDTWKIGDKTGTGSNGSAADIAVVWPPGHGAILVAAYLTQ -AKAPVSEINPVFAEVGKIVG--- ->[subseq from] SED family class A beta-lactamase n=1 Tax=Citrobacter farmeri TaxID=67824 RepID=UPI000F65CED2 ---QVQQKLAALEKQSGGRLGVALINTADRSQI-LYRADERFAMCSTSKTIVVAAVLKQSE -TQHDILQQKMTIKKTDLTNWNPVTEKQVNKEMTLAELSAATLQYSDNTAMNKLLEHLGGT -GNVTAFARSIGDATFRLDRTEPELNTAIPGDERDTTSPLAMAKSLHKLTLGNALADMQRA -QLVAWLKGNTTGGQSIRAGLPESWVVGDKTGGGDYGTTNDIAVIWPEDRAPLILVTYFTQ -PQQDAKGRKDILAAAAKIVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora citrea TaxID=47855 RepID=A0A1C6UQV2_9ACTN -----EHEFRQLEKRFDARLGVYAIDTGSGRTV-EYRADERFAYASTFKALAAAEILDETT ---DAELDRVVRYSADDLVTYSPITERHVATGMTLRAIADAAVRYSDNTAANLMLRHLGGP -QKFEKELREVGDKVTDPARYETELNEARPGDRRDTSTARALAESLRAYAVGDALEPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDASYDNALIAEATKAVLAGw ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2E2AE5 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSTRSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E36D4F --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKHN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. GV021 TaxID=2135749 RepID=A0A2T5ZJ55_9PSED ---AIQQQLADLESRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAAHVLARVD -RKQEDLSRRIVYSAEQLVAYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANLLLDSMGGP -EGLTAWLRSIGDTRTRLDRREPDLNENRPQDLRDTTTPVAMLHTLNTLVLGDELTLPSRD -QLTAWLVNNQTGDKKLRAGVSGGWRVGDKTGSGSNNATNDVAVIWPGDRPPILVTAYYTG -SKASADQINAVMADIGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=Phytobacter diazotrophicus TaxID=395631 RepID=A0A4R4AYV1_9GAMM ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTLAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE -TQATMDDRNKKIADIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. tmac-D7 TaxID=2591462 RepID=UPI001144BF69 -----DQAFVQLEDEYDARLGVYAIDTGTGRTI-AYRPDERFAYASTYKALAAGAVLLKSS ---IEELDEIITYSSNDLVTYSPITEKHVSTGMTLREISDAAVRYSDNTAGNLLFKRLGGP -AGFEAILKQIGDTVTQADRYETELNEAVPGDDRDSSTPRALATSLHAFTVGDALPANKRT -ILTDWLRGNTTGDELIRAGVPEGWTVGDKTGAGNYGARNDIGIVWPPNGDPIVIAILSSR -DTKDAGYDNSLIAQAAKTALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. CDB3 TaxID=360310 RepID=A0A1V9W5V4_9BACI ---ATYQEFSQLEKEFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYSKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAKVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI00037C3C79 ---TIRARLREIEADSGGRLGVAIVDTTSGLHT-GLHADERFPMCSTFKLLVAGAILARVD -RGEENLQRRIVYSQSELVPNSPATSKHTRARMSVGDLCKAAITLSDNTAANLLLASFGGP -AALTEFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGHGPILVAVYLTE -TAGDAARCNAAIASVGALVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas melonis TaxID=56456 RepID=A0A2S7DHQ4_9XANT ---MLRAQWAEIERGTGGRLGISVLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD -QGKLSLAQPVGIRASDMLAHAPVTERHVGGSLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTAFLRSIGDAKTRSDRYEPEMNRFAPGEPRDTTTPAAMASTLRTLLLGDALAPASRK -QLTDWMIDNRTGDDCLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPKGPPLLLTTYLNG -AKVDDAARDAALKQVAATVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE6_9BACT ---ETLVKVKDAGDQLGARVGYIELDLNSGKILeSFRPKERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. K2R01-6 TaxID=2320861 RepID=A0A418W7H8_9SPHN ----FARRIAALEAANGGRLGVAVLDTSSGARF-SHRGDERFPMCSTFKFLLAAATLARVD -RGQEKFDRRIRYAADQIVTHSPVTSEHVGAPLTVGELCAATMTTSDNTAANLLLTALGGP -TAFNAFARNLGDRYTRIDRIEPWLNEAMPGDLRDTTTPAAMLGNLRRLLTRSTLTPGSRD -ILIGWLVANQTGGTRLRAGVPADWRVGDKTGAGERGTVNDIGILWPAGRAPILVASYLTA -SPLPFETNSAVHADVARAIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK315 TaxID=2512135 RepID=A0A4R3GEY1_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGNNRLRAGLPKDWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEIGKIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 105MF TaxID=1151120 RepID=UPI00037EC1F9 ---TVNHSFARLEKEFDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGILLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium giardinii TaxID=56731 RepID=UPI00035E8157 --nDINRQLASLEKRTGGRLGVSVLDTKSNVSF-GHRQDERFAMCSTFKALAAAFVLARVD -KGQETLGRRIVVSKADLHAHSPVAEKHVGDGMTVGELCDAAVTYSDNAAANLILASFGGP -DGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMMRTLGKLLLEDVLSPSSRD -QFAAWLVANRTGDRRLRAGLPTNWTIGEKTGTSGHGEAGDVGFMRPPKGQTILASVYIAE -APKPVKELEPIFAEVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax sp. OK605 TaxID=1855317 RepID=UPI0008EB3AC7 ----AEAQLAELERASGGRIGVAGLHTGSGARF-QHRAHERFPMCSTFKLMLAAAVLERSA -KDASLLSRQLSYGKSDLIANSPVTEKHVATGMNVADLCAATIQYSDNAAANVLLKLLGGP -PEVTAFSRRIGDQTFRLDRTEPELNTSIPGDLRDTTTPAAMSDSVQRLVLGDALGAPQRD -QLKTWLLGNTTNKERFLAGVPAGWKVGDKTGGGSYGSNNDVGVLWPPAGAPLVLSVYLTF -PEKDAKTRNDVVASATRIAVT-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009ABFFF8 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKDATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0014422AF1 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAALCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVATVYISE -TTVPVTELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B51AEC --qATHKEFSKLEQKFDARLGVYAIDTGSNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVNYSPVTEKYVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAAIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] 3G61_DB15V4 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFC1 ------VKVKDAADQLGARVGYIELDLNSGKILeSFRSEERFPMMSTFKVLLAGAILSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP -KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG -SQATMDELNRQIAEIGASLIKGw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. E(2018) TaxID=2502239 RepID=UPI0010F8445D ---KTEKKFMQLEKQFDARLGIYAIDTHTNRTV-TYRPDERFAYTSTFKALAAGVVLQQKS ---IEELEEVITYTEDDLVTYSPITEQYVDTGMTLREICDAAIRYSDNTAGNLLLQELGGP -NGFEKALRDIGDNVTEADRYETDLNSAIPGDIRDTSTARALAINLKAFTADDVLPNDKRT -ILTDWLRRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNREPIIIAILSSR -DTQNATYENELIAKAAKVALNAf ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4F6K8_9BURK ---ALARAMQEIEASVGGRLGVALLDMATGRQG-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGQSDLMEYSPATERHVGGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LGLTAWLRSLGDSQTRLDRMEPALKDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -QMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 4M9327F10 TaxID=2502223 RepID=UPI0010F7144B -----EARLAQLEQSAGGRLGVFALNTADGTQI-GHRADERFPFCSTFKVILIGAILARSA -QAAGLMQQRIHYTAGEVVHYSAVTAEHVSDGMTVAELCAAAIQRSDNTAANLLIRLLGGP -DAVTAYARSLGNPVFRLDRLETALNDAVPGDPRDTASPAAMARSLQALTLGEALPLAQRT -QLLDWLRGNRMGAQRIRAALPAGWTSGDKTGTGDYGTANDLGLIWPPSRAPILLGIYHTQ -AQQDAKARDDVIAAAARIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain Q1) TaxID=361100 RepID=B9J113_BACCQ --qATHKEFSQLEKKFDARLGLYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HY001 TaxID=2597691 RepID=A0A556CAI5_9BACI ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIEDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000E2CC650 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAELPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAVIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=Q5GJ48_RAOOR -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLNVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=unclassified Raoultella TaxID=2627600 RepID=UPI0013309E41 -hdATVNQVKAAERQLKARVGYAELDLASGRLLaSYRPGEHFPMMSTFKVPLCAAVLARVD -AGEEKLDRRIRYRQQDLVDYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTSTPQAMAKTLRNLLTGSVLSAASRQ -QLRSWMVDDKVAGPLLRSTLPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNRQIAGIGETLVKHw ->[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter sp. wls613 TaxID=2576436 RepID=UPI0010CA8DE3 --pTTLNKVKEAESQLTARVGYAELDLTSGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKELLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE -SQATLEERNRQIAGIGATLIQHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella sp. BIGb0138 TaxID=2485115 RepID=A0A4R3ZF99_9ENTR -heATVSKVKEAESQLQARVGYAELDLSSGRLLtGYRSAERFPMMSTFKVLLCGAVLSRVD -TGEEKLDRRIDYRQQDLVEYSPVTEKHLSDGLTVAELCAAAITLSDNTAANLLLATLGGP -QGLTAFLRRSGDRTSRLDRWETALNEALPGDARDTTTPEAMAQTLRQLLTGNVLSAASQR -QLQRWMVDDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIVAALGPDGKASRIVVIYLTE -TKASMDERNKQIAAIGETLVQRw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00027AAF2B -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEGLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC00469 TaxID=2487415 RepID=A0A3R9SQI6_9ACTN --qEAADRLGALEDRYGARLGVHARNVRTGQVV-AHRADEVFAMCSVFKTFAAAAVLADQD --RCTPLDRLVAYPPADLLPNSPRTEEHVDTGMTVDDLCAAAIRYSDNTAGNLLLRQIGGP -AGLTRFFRSLGDRVSRLDRWEPDLNTAVPGDPRDTTTPQALGRLLERLTLGDALAAADRA -RLVDWMKGNTTGDGRIRAGVPQGWTVADKTGTGSYASAHDVGVAWTTRSTPVVLVVLSSK -ETADAPVDEALLADAARVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF31A57 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGALLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013252704 ------------ESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -XGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1E2I3_BACCE -----YKEFSQLEKKYDARLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN -IFTEWMKGNATGDKLIRAGVPTNWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAKVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. S1 TaxID=1641859 RepID=UPI00131D52A8 ---AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD -HGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAALTLSDNTAANLLLASFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPSAMLGNLRELLLGERLSSLSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE -TSGDAARCNAAIASVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Shigella sp. FC1967 TaxID=1898041 RepID=UPI00086F3D4A --nTIEAQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAILKESE -KQAGLLDKNITITKSDLVAYSPITEKHLVTGMSLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQVLALGDALGGSQRQ -QLVTWLKGNTTGDHSIKAGLPKQWIVGDKTGSGDYGTTNDIAVIWPDNHAPLILVVYFTQ -QRQDAKHRKDIIAKVVEIVTKPf ->[subseq from] class A broad-spectrum beta-lactamase OKP-B-21 n=1 Tax=Klebsiella TaxID=570 RepID=UPI000B4184C2 ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNEQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A162P3V9_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIEDRVTKSDRLETELNEAIPGDKRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q3YA67_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNEQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. b14 TaxID=1761775 RepID=A0A1R3VVL8_9BURK ------EALAVLEARMGGRLGVCAIDTGSGARL-VHRAEERFPFCSTFKAVLAAAVLARSG -DTSDWLSQRVRYGSADVVSYSPISGQHVGAGMRIDEMCAATLQYSDNTAANQLMKVLDGI -DAVTAFARSVGDATFRLDRWEPELNTAIPGDVRDTSTPAAMADTLRAVMLGNVLRPWQQQ -RLQQWMLGNRTGDKRIRAGVAAQWRVADKTGTGEYGTTNDIGVLWPPERAPIVLSIYFTQ -PQQDAPARDEAIEQATRIVVD-- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A5Q2F6E6_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEDBACE ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTSDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Citrobacter portucalensis TaxID=1639133 RepID=UPI0008F83F29 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTSGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Rhizobium TaxID=2613769 RepID=A0A437N5N5_9RHIZ --dDIEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFALARAD -KGEESLDRRVTYGRDKLVDYSPLSEKHAGADMTITELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSILTEASSD -RLIAWLVASTTGGERLRAGLPKEWKVGDKTGTGQNGSLGDIAVIWPPDRSPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI000B3F91C6 ---TIRARLREIEADSGGRLGVAIVDTTSGLHA-GLHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVGDLCKAAITLSDNTAANLLLASFGGP -AALTEFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE -TAGDAVRCNAAIASVGALVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI0003708DC8 ----FARAVQEAEASVGGRLGVALLDVATGRQD-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYRKSDLMEYSPATERHVDGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LALTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSSAARA -RMLGWLVGNRTGDRRLRAGMPEGWRVGEKTGTGPRGTSNDIGLFWPPDRDAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium indicum TaxID=1775910 RepID=A0A0J6RJ49_9RHIZ ---DAVARLAQFERRDGGRLGVEVRDTATGRRF-GHRADELFPMCSTFKAVAAAAVLARAD -KGQDDLNRRIAYTRDDLLSYAPVTSKHVESGLTLAELCAAAVVWSDNTAANLMLATLGGP -GGITTFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGKALSAESRT -KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIARSf ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia TaxID=1822464 RepID=I5CU60_9BURK ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRTIAYSKEVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGDHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVAAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4L245_BACCE -hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRQ -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK -EEKEATYDNQLIAEAAEMIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=R4S362_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSACWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSLRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSSVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. OK202 TaxID=1884311 RepID=A0A1H7E6S3_9BURK ----AEAQLAELERASGGRIGVAGLHTGSGARF-QHRAHERFPMCSTFKLMLAAAVLERSA -KDASLLSRQLSYGKSDLIANSPITEKHVATGMNVADLCAATIQYSDNAAANVLLKLLGGP -PEVTAFSRRIGDQTFRLDRTEPELNTSIPGDLRDTTTPAAMSDSVQRLVLGDALGAPQRD -QLKTWLLGNTTNKERFLAGVPAGWKVGDKTGGGSYGSNNDVGVLWPPAGAPLVLSVYLTF -PEKDAKTRNDVVASATRIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A443WXH8_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY1_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. TaxID=391 RepID=A0A5C7U540_RHISP ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADADMTVAQLCGAAITLSDNTAGNLLLESFGGP -AALTAWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLVNWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVGRIVT--- ->[subseq from] class A broad-spectrum beta-lactamase OKP-B-36 n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI00073B170F ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=J8X555_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDVKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679H1W8_9BACI -----NNSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVGTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFILGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBB9BE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKESLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATQIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BF4356D ---TVNHSFARLEKEFDAKLGIYALDTGTNQII-TYRSDERFAYASTHKALAVGILLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase SHV-34 n=1 Tax=Escherichia coli TaxID=562 RepID=BLA34_ECOLX ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADGRFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase LEN-58 n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2CB9BC ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLFDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Shigella sp. FC1655 TaxID=1898038 RepID=A0A1D3DEB3_9ENTR --nTIEAQLSTLEKYSQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAILKESE -KQAGLLDKNITITKSDLVAYSPITEKHLVTGMSLAELSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQVLALGDALGGSQRQ -QLVTWLKGNTTGDHSIKAGLPKQWIVGDKTGSGDYGTTNDIAVIWPDNHAPLILVVYFTQ -QRQDAKHRKDIIAKVVEIVTKPf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_331 TaxID=1969379 RepID=A0A328LVH6_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILTSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1JIQ2_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVGTGMTLGAIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDNRDTSTAKAMATNLKDFTVGNALPDDKRS -ILTDWMRGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8RST3_BACCE ---TVNHSFAKLEKEFDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDERIVYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVPPGDTHDTSTPKALATSLQAFALGDVLSTEKRE -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD102 TaxID=1053228 RepID=J8JHT5_BACCE --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKHN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009BA7A54 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=UPI000A0612D4 ---QIHRKFADLEHKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTFKALAAGALLQHYS ---LDQLDELVKYSREDIVTYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLKKLGGP -KGFETALRQIGDNVTQADRYETELNSAVPGDPRDTSTPKALAASLRAFAVSDLLPSEKRT -ILIDWMRGNATGDALIRAGAPKGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAILSSR -DTQNATYDNALIAEAAKVALN-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-27 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1P8C558_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPRSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033E6E3 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B1AQH6_BACCE -hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRQ -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK -EEKEATYDNQLIAEAAEMIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Thalassospira xiamenensis TaxID=220697 RepID=UPI000DED6607 --dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD -LGTETLDRRIIYSVEDLVTYSPTTEKHVDSGMAIGELCEATLHLSDNTAANLILDALGGP -DELTAYLRDIGDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ -LLEDWLTGNQVGGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH4_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00143185C3 ----LRAQWAEIERGTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPARAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. H4 TaxID=2035449 RepID=A0A2A6R6S8_9RHIZ ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVTYGKDKLVDYSPISEKHAGADMTIAELCDAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPAAMLDTLGNLTLGSVLTEASCN -RLIACLVASTTGGERLRAGLPADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKDLNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZRK9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNXGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQI----------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium esperanzae TaxID=1967781 RepID=A0A246DT74_9RHIZ ---NIERRLATLEKRIGGRLGVSVLDTQTSISF-GYRGGETFPMCSTFKALAAGFVLARVD -KGQESLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLAEPSSD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPAKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2H3NF61_9BACI ------DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSKH -DKEDAKYDDKLIAEATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylibium sp. CF468 TaxID=1500262 RepID=UPI000647C16D ------PRWAAIEAESGGRLGIAVLDTATGRFD-GHRLGERFPMCSTFKWLAAALALQRVD -AGLERLDRRVAVRREMLVNHSPVSEKHVGGNMSIAELCEAAVLVSDNAAANLLLASFGGP -AAITRYARTLGDTQTRLDRTEPALNEARPGDPRDTTTPRSMAIALQSALLGTALSEASRA -RLVAWMEAVRTGTDRLRAGLPPGWRAADKTGTGARGTTNDVAVVWPPNRAPLVITAYLTD -SQADAKRLNAALAAVAREAA--- ->[subseq from] Beta-lactamase n=1 Tax=Curvibacter sp. TaxID=1888168 RepID=A0A353Y3B1_9BURK ---------REIEAEASGRLGVAVLDTATGHLQ-GHRLDERFPLCSTFKWLLGAHVLRRVD -LGLERLDRVIVYGPDAIIPWSPVTAQRVGQGMTLAELCEATITLSDNAAANLILQTLGGP -QGWTQYVRSLGDTVTRLDRTEPELNAATPGDPRDTTSPRAMVALLQGVVLGDALTPASRA -QLVTWMQATQTSGQRLGAQLPAGWRLGSKTGTGARGSTNDVGVYWPPDRAPIVVAAYLTQ -SPAAEATRNRAIARVARAVIS-- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens BA1 TaxID=1393736 RepID=A0A022PLW1_PHOLU ---SLHKQLAELENSTKGRLGVTLINTVNGQEI-QYRGDERFPFCSTFKLILVAAVLHKSM -SQSELLAKHIHYRESDLLSYAPIARKNLNQGMSVAQLCAATVQYSDNTAANLLIKELGGL -EVVNHFTQGIDDPAFRLDRCEPDLNSAIPGDLRDTTTPAAMATSVRKIVLGEVLAAPQRE -QLIVWLKGNTTGDASIRAGAPADWVVGDKTGGGDYGTTNDVAVLWPPKGAPVVLAVYFTQ -PQQDAESRRDVLASATRLVMAH- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. GAS332 TaxID=1882750 RepID=A0A1N6LHK4_9BURK ---AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD -HGQEDLERRVVFSKSDLVPYSPATSQHTRERMSVADLCKAALTLSDNTAANLLLASFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPSAMLGNLRELLLGERLSSLSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE -TSGDAARCNAAIASVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA58A2 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---MEDLNQRILYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKFDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q1WBW3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASWQ -QLIDWVEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5E4AA ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKIVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEIGKIVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFRVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHPTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY6_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. viciae TaxID=387 RepID=A0A4R0BL75_RHILV ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFSMCSTFKALAAAFVLARAD -KGEENLDRPVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB24CE ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKIVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEIGKIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudolabrys taiwanensis TaxID=331696 RepID=A0A345ZT82_9RHIZ ----AETKLRALEHQHGGRLGVFVRDTGSQAQL-AHRADERFPMCSTFKFLLAAAVLKRVD -DGKTRLDHEIDYGDKDLLDYAPVAKQHVASGLSVAALCAAAVVWSDNTAANLLLNHLGGP -QAVTAYAHSLGDMLTRLDRMEPALNTVPAGDPRDTTSPRAMVGDLQAILVGDALSPVSRQ -RLEDWMVAAQTGRERLRAGVPATWRVGDKTGTGPNGSTNTIAILRPPQRAPLLAAIYYTS -SKAPLKDREAVHAEIGRLIVESf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A5B0VV53_RHITR ---DVDKQLTDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHVGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGPILVTTFIAE -ATASARDIEAVFAEVSKIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC69MF TaxID=1449047 RepID=UPI0012E00CDF ----TNQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDKLIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Chelativorans sp. lm92 TaxID=2681495 RepID=UPI0013D2BB13 ---DAEAKLAALERAHDGRLGVAILNLATGARA-GHRSDERFLMCSTFKALAAALVLARVD -RGEEALDRRITFSKADIAAWSPATETRVGGKMTVAELCEAAVTLSDNTAANLLLRSFGGP -QALTAYARSLGDEVTRLDRFEPALNEHGPDDIRDTTSPAAMLETLRTLLFADVLSKPSRS -RLAAWLIANKTGGARLRAGLPENWLVGDKTGTSGSGAVNDIGVAWPPDRAPIVVTAYCEL -PAISGDERNAVIAEIGRIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001249AFD0 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-SYRPNKRFAYASTYKALAAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDNVTVANRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVDDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A150TNI2_SORCE ----AAPALARIEAQVGGRLGVAALDTATGARI-AHRAAERFAMCSTFKTLLAACILARVD -QGQLRLDHRVTYRASDLLDHAPVTRAHLAQGLTVEELCAAVVEISDNTAANLLLAQIGGP -AGLTAYLRGLGDEVTRLDRNELALNENVPGDPRDTSTPDAMTDTVRAILVGDALQRASRE -RLASWMVRSTTGLARLRAGLPKDWVIGDKTGTGN-GIANDVAVAWPPSRPPIVIACFVDA -PSASADARNAAHADVARAVAEAf ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia terrae TaxID=311230 RepID=A0A2I8EIK4_9BURK ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKDQLERKIVYSKDVVVANSPVSGPRAGSDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRTTRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE -QLTAWLAANKTGDTRLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=A0A658AX17_9ENTR ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRHIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium S05 TaxID=2052938 RepID=A0A2S0V8X0_9ENTR ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRHIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. Irchel s3a18 TaxID=2009053 RepID=UPI000BA39F7F ----LSRTLTEIETHLNARLGATIIDTESGKVW-SHRADERFPMTSTFKAFACAGLLARID -AGKEDPNRRVVVHEDDLVTYSPVTEQRVGGDMTLSELCEAAMSMSDNTAANIILGTLGGP -DGFTRFMRSLGDDITRLDRWETALNEAMPDDPRDSTTPEAIARSLQELVLGTKLSPSSRQ -QLENWLVGNKVGGPLLRAGLPANWRIADRTGAGGYGSRSIVAVIWPPERKPAVVAIYITE -TEASMDERNAGIAEIGRMLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG2_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDMVEYSPVTEKHLTDGMTVRGLCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAEPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F044B34 ----IQQQLADLEHRHGGRLGVAILNTASQRLI-SHRGDERFALCSTFKCLAAACVLSRVD -QTQEDLARRIAYSAEQLVPYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANVLLDSLGGP -DALTAWLRSIGDTQTRLDRREPELNENRPGDPRDTTTPVAMLHTLNTLVLGSELTLPSRD -QLTAWLVNNQTGDKKLRAGVPAHWRVGDKTGSGANNASNDVAVIWPGDRSPILVTAYYTG -SKASGDQINVLMADIGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE53E26 --dEINRRMEALEKEIGGRIGVSAIDTETSISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQENLERRVVYEQDKLVTYSPETEKHVGGEMSIGELCEAAITLSDNTAGNLLLESFGGP -AELTKWVRTIGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLVEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVLWPPGHGAILVAAYVTQ -AKAPLSEINPVFAEVGKIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 174MFSha1.1 TaxID=1502749 RepID=A0A1I7KMR3_9RHIZ ---DAVARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD -AGKEDLNRRIAFSRDALLSYAPVTTKHVETGMTLAELCGAAVVWSDNTAANLMLDTLGGP -GGITAFARAHGDTVTRLDRTEPTLNTAIAGDVRDTTSPAAMVGLLENVLLGRALSAESRD -RLIGWMHDSPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEIGRLIARSf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus bacterium TaxID=2053512 RepID=A0A506QPE0_9BACI --qATHKEFSQLEKKYDARLGLYAIDTGTNEII-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYKKEDLVNYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIVVILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HMSC76G11 TaxID=1608910 RepID=A0A1S1FP27_9BACI -----NHDFDKLGEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAANLILKQLGGP -TGFKKALEEIGDNVTNPERYEPDLNEVNPGETHDTSTPRALAASLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDELIAEATKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF62AE6 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSNERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -DKEDAKYDDKLIAEATQIVLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. ap11 TaxID=1761799 RepID=A0A1H8VK65_9RHIZ ---DAAARLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD -KGQDDLNRRISYGRDDLLSYAPVTSKNVATGMTLAELCAAAVVWSDNTAANLMLATMGGP -AGITAFGRAHGDGVTRLDRTEPTLNTAIAGDPRDTTTPAAMVGLLDNVLLGQALSAESRG -KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDTLHAEVGRLIARSf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00032E0E11 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDKGMALKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium indicum TaxID=1775910 RepID=A0A147FEF5_9RHIZ ---DAVARLAQFERRDGGRLGVEVRDTATGRRF-GHRADELFPMCSTFKAVAAAAVLARAD -KGQDDLNRRIAYTRDDLLSYAPVTSKHVESGLTLAELCAAAVVWSDNTAANLMLATLGGP -GGITTFARAHGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAMVGLLDNVLLGKALSAESRT -KLVGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIARSf ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia strydomiana TaxID=1245417 RepID=A0A4R0X0B9_9BURK ---TIRARLREIEADSGGRLGVAIVDTTSGLHT-GLHADERFPMCSTFKLLVAGAILARVD -RGEEDLQRRIVYSQSELVPNSPATSKHTRERMSVGDLCKAAITLSDNTAANLLLASFGGP -AALTEFARSLGDGITRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELVLGEHLTSSSRA -QLLAWLAANETGGERIRAKLPKDWGVGDKTGTGDHGTANDVAIVWPPGRGPILVAVYLTE -TAGDAVRCNAAIASVGALVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI000F5DBA6E ---TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWLKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A679JI96_VARPD ---SAESQLAELERASGGRLGVTGFDTGTGARI-QHRAHERFPMCSTFKLMLAAAVLERSA -KEPDLLARQLSYGRSDLIANSPITEKHVTTGMRVAELCAATIQYSDNAAANVLLRLLGGP -GEVTAFSRRIGDQVFRLDRTEPELNTSIPGDMRDTTTPSAMSDSVQRLVLGDALGAPQRD -LLKTWLLGNTTSKERFMAGVPAGWKVGDKTGAGSYGSNNDVGVLWPPAGAPLVLSVYLTF -SQKDAKTRNDVVAAATRIAVT-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFD0 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMXTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0007ECC635 ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLVQRVKIRASDMLEHAPVTERHVGGLLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. SLFW TaxID=2683259 RepID=UPI001412A41A ---SLQQRLADLEHRHGGRLGVAILDIGSQRLV-SHRGDERFAMCSTFKALAAAHVLARVD -RKEEDLSRLIVYGKDQLVPYSPTTEKHTGEALSVGSICEAAVTLSDNTAANLLLDSFGGP -AGLTQWLRWTGDEVTRLDRREPELNENRAGDPQDTTSPIAMLQTLRSLIFGDVLTGASRD -QLIAWLVSNTTGDKKLRAGLPKKWRVGDKTGSNAKNADNDVAVIWPSSRAPLIVTVYYSE -SRANAEQVNAVMADIGRIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J8HJS9_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKDATYDNKLIADAAEVIVK-- ->[subseq from] Carbapenemase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0A8P2Z6_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPRSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB33FA ---DVEARLAELEKRTGGRLGVSVLDTATNISF-GCREDERFAMCSSFKALAAGFILARVD -QGAETLDRRIVVAQKDIIAHSPVTEKHLGGEMTIADLCAATMTTSDNAAANLLLESFGGP -SALTAWLRMIGDETTRLDRNEPTLNEAKKGDPRDTTTPAAMLETLGNLAFGPALTADSRK -RLIEWMVANTTGDERIRAGLPKGWKVGDKTGTNATGSASDIAVVWPEGRAPLLIAVYIAE -ATAPLSVLNTVFADVGRVAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=UPI001441830A ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLGRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKSDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013DA0307 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTFGNLTLGSVLTEASCD -KLIAWLVASATGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. ERR 942 TaxID=2572676 RepID=A0A560LPX8_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKEDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATADAKDVEAVFAEVSKIIVD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium multihospitium TaxID=410764 RepID=A0A1C3V044_9RHIZ ---DVDKQLVDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAAGFVLARVD -QGTEKLDRRITYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVSKIIVD-- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A4R3R406_9RHIZ --dDIERRLGELEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYDRDKLVSYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESVGGP -KALTKWLRSIGDRATRLDRWETALNEGKKGDPRDTTTPDAMLDTLGNVALGSVLSEPSRE -KLIAWMLANTTGNARLRAGLPGDWKVGDKTGTGDNGSAADIAIIWPKGRGPVLVTAYIAE -ARAPVKELNLVFVEVAKIVA--- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000667C644 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHXRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. ATCC 53434 TaxID=2059672 RepID=A0A2H5DZ93_9NEIS ----AAETFAKIEKDFGGTIGVHAIDTGSGAVV-SYRAEERFPLCSSFKGFVAAATLARSQ -QQAGLLDKRIAYGEDALISWSPITRKHQATGMTVAGLCAATVQYSDNAAGNLLLKELGGP -AGLTAFMRSIGDRTFRLDRWEPELNTAIPDDARDTSSPRAVAESLRKLALGSALAAPQRR -QLNDWLKGNTTGDKRIRAEVPAGWKVGDKTGTCGYGTANDYAVIWPKGRAPIVLAVYTKG -RDKNLKPSDAVIAAAAKAALE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BAE7F87 --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMEDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B0FA7 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAVAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8RPD3_BACCE ----THREFVQLEKKFDARIGVYAIDTGTNRTV-AYRPDERFAYTSTFKALAAGAVLQQNS ---IDQLNKVITYTKDDLVTYSPITEKHLDTGMTLWEIADAAIRYSDNTAGNLLFKELDGP -KGFEKKLRQIGDRVTKVNRFEPDLNEATPGDIRDTSTAKALATNLKAFTVDNVLPTDKRK -ILTDWMRGNTTGDQLIRAGVPKDWEVGDKTGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKNATYNNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Providencia stuartii TaxID=588 RepID=O68473_PROST ---ETLVKVKDAEDKLGARVGYIELDPNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMRTTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRCALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Kluyvera sp. Nf5 TaxID=2116543 RepID=UPI000D178FD7 ------ETVKKAEDQLNARVGYAELSLSNGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDRMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE -TQATMDERNKKIADIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Sinorhizobium sp. A49 TaxID=1945861 RepID=A0A1V3QQX0_9RHIZ ---DVDARLAELEKRTGGRLGVSVLDMDTNISF-GCREDERFAMCSSFKTLAAGFILARAD -QGAEKLDRRLVVAQKDIIAHSPITEKHVGGEMTIADLCAATMTTSDNAAANLLLESFGGP -QALTAWLRTIGDDTTRLDRNEPTLNEAKMGDPRDTTTPAAMLETLGNLAFGPALTEPSRK -LLIEWMVANTTGDQRIRAGLPKGWKVGDKTGTNSTGSASDIAIVWPEGRGPLLIAVYIAE -ATAPLAELNTVFADVGRMAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SN10 TaxID=2056493 RepID=A0A2N1JYT8_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQYS ---TEKLNDVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSNK -DEKGATYDNQLIAEAAGVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF91C1B -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKTLATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. Irchel s3b6 TaxID=2009078 RepID=UPI000BA444D0 ----LSRTLTEIETHLNARLGATIIDTESGKVW-SHRADERFPMTSTFKAFACAGLLARID -AGKEDPNRRVVVHEDDLVTYSPVTEQRVGGDMTLSELCEAAMSMSDNTAANIILGTLGGP -DGFTRFMRSLGDDITRLDRWETALNEAMPDDPRDSTTPEAIARSLQELVLGTKLSPSSRQ -QLENWLVGNKVGGPLLRAGLPANWRIADRTGAGGYGSRSIVAVIWPPERKPAVVAIYITE -TDASMDERNAGIAEIGRMLA--- ->[subseq from] Beta-lactamase n=1 Tax=Hydrogenophaga sp. LA-38 TaxID=2294117 RepID=A0A372ELX0_9BURK ---ALDAAARALEAKSRGRLGVHILDTADGREW-GHRSDERFLMLSTFKTLAAALVLRRAD -QGKAPLSKRVRYRQRDLVQWSPVTEKHVGGRLSLAQLCEATITTSDNTAANLILREVGGP -AALTAFLRGVGDPVTRLDRMEPELNEPSPGEDLDTTTPRAMARTLRTLLLGEALSPASRE -QLAAWLKANTTGDRRLRAGVPPSWGIGEKTGTAGE-SANDAGIVWPPGRAPLLVSAYLAD -SPAGAAAREQALAGVGRLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Hydrogenophaga sp. 70-12 TaxID=1895769 RepID=A0A1Q3QHQ4_9BURK ---ALDAAARALEAKSRGRLGVHILDTADGREW-GHRSDERFLMLSTFKTLAAALVLRRTD -QGKAPLSKRVRYRQRDLVQWSPVTEKHVGGRLSLAQLCEATITTSDNTAANLILREVGGP -SALTAFLRGIGDPVTRLDRMEPELNEPSPGEDLDTTTPRAMARTLRTLLLGDALSPASRE -QLAAWLKANTTGDRRLRAGVPPSWGIGEKTGTAGE-SANDAGIVWPPGRAPLLVSAYLAD -SPAGAAAREQALAGVGRLLA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7D9T1_BACAN ---TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTDKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDANYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium mesoamericanum TaxID=1079800 RepID=UPI000421354C ---DINRRMDALEKAIGGHIGVSAIDTDTNISF-GYRETERFPICSTFKVLAAGLVLARVD -KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEVKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVVWPPGHGAILVAVYVTQ -AKAPVSEINPVFAEVGKVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium hidalgonense TaxID=1538159 RepID=UPI000FEC8014 --dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD -RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKDLNPVFAEVGKMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. JKLM19E TaxID=2583232 RepID=A0A5R9N1R3_9RHIZ --dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD -RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKDLNPVFAEVGKMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM597 TaxID=754764 RepID=I9N6U1_RHILT --dDIQKRLAALEKRTGGRLGVSVLDTGTSISF-NYRGSEAFPMCSTFKALAAGFVLARAD -KGEESLDRRVTYGKDKLVDYSPLSEKHADADMTITELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLTEASAD -RLIAWLVASTTGGERLRAGLPSEWKVGDKTGTGPNGSLGDIAVIWPPNRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDA8373 --nDIEKQLAALEKRTGGRLGVFVLDTKNNVSF-AHRPDERFAMCSTFKALAAAFVLARAD -MGEEKLDRRVPVLKKDLLSYSPVVEKHVGGGMTVRELCDAAVTYSDNAAANLLLASFGGP -KGLTTWLRSIGDETTRLDRTEPELNEAKVGDPRDTTTPMAMTQTLGRLLLQDVLSPSSRD -QFTAWLVANTTGDRRLRAGLPQDWTIGEKTGTSGRGEAGDIGFMRPREGHTILASVYIAE -GKKPTKELEPVFAEVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylibium sp. YR605 TaxID=1500265 RepID=UPI0006461962 -------RWAAIEADSGGRLGIAVLDTGTGRFD-GHRLDERFPMCSTFKLLAASLALQRVD -AGLERLDRRVAVRRGMLINHSPVSEKHVGDHMSIAELCEAAVVVSDNAAANLLLASFGGP -AAITRYARTLGDTQTRLDRTEPALNEARPGDPRDTTTPRSMAIALQSALLGSALSDASRA -RLVAWMEAVRTGTDRLRAGLPPGWRVADKTGTGARGSTNDVAVVWPPNRAPLVITAYLTD -SKADAKRLNAALAAVAREAAGRf ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI00128D9D3A ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -NAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000987BC53 --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0009BDFCE2 --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSNK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0011A18FF3 ---TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTDKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDANYDDKLIAEATKIVLD-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D746BE6 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E2D11E ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0A1ISX2_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8DKN6_9BACL ---ALDPQFGQLEKDFGARLGVYAIDTGSGREI-TYRGEERFAFASTFKALAAGAVLKQST ---DEQLHVVINYTSDDLVTYSPVTEKHVQTGMTLSEISEAAIRYSDNTAGNLLLKQLGGP -EGFEKILRELGDQVTSPVRYETELNEAIPGDTRDTSTPKALAGTLQKLTLGDVLPQEKRS -MLINWMLGNETGDKLIRAGAPKDWVVADKSGAGSYGTRNDIAVIWPANGDPIVMAILSST -DKQDAPYDNALIEKAAKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F03E51A ----IQQQLADLEHRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAACVLSRVD -QKQEDLARRIVYSAEQLVPYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANVLLDSLGGP -DALTAWLRSIGDTQTRLDRREPELNENRPGDPRDTTTPVAMLHTLDTLVLGSELTLPSRD -QLTAWLVNNQTGDKKLRAGVPAHWRVGDKTGSGANNGSNDVAVIWPGDRSPILVTAYYTG -SKASGDQINVLMADIGRLVA--- ->[subseq from] PLA/ORN/TER family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000CF30E09 -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYRAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -LGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00102FE186 ---NIEHRLAALEKRTGGRLGVSVLDTDTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVTHGKDKLVDYSPLSEKHAGTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -AALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAVLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMVVE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D6FDF39 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAVIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Ensifer adhaerens TaxID=106592 RepID=UPI000CF037DA ---DIDRRLAELEGRTGGRLGVSVLDTQTNISF-GRRENERFAMCSSFKALAAGFILARVD -QGTETLDRRIPFQEKDLVTYSPVTEKHVGGAMTIAELCAATITTSDNTAANLLLDSFGGP -SALTAWLRSIGDENTRLDRIEPALNEAKKGDPRDTTTPAAMLDTLGKLTVGSALTESSRK -QLNAWMVANTTGDLRIRAGLPAAWRVGDKTGTNATGEASDIAIVWPEGRSPLLITVYIAE -ATAEVKDLNPIFAEVGRMAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Proteus sp. FJ2001126-3 TaxID=2050966 RepID=UPI000D6921A0 --nTIEEQLSTLEKYGKGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVATVLKESE -KQAGLLDKNITIKKSDLVVYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -AKVTQFARSINDVTYRLDRKEPELNTALHGDPRDTTSPIAMAKSLQALTLGDALGLSQRQ -QLVTWLQGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKAAEIVTKPf ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. BK460 TaxID=2512152 RepID=A0A4Q7LFI8_9BURK ---SAETQLAALESASGGRLGVVGLHTGSGARI-QHRAHERFPLCSTFKLMLAAAVLERST -QDGGLLSRNLSYGKIDLIAHSPVTEKHVATGMTVGALCAATIQYSDNAAANVLLKMLGGP -AAVTAFARRIGDQAFRLDRTEPELNTSIPGDLRDTTTPAAMTDSVQRLALGDALPTVQRD -QLRTWLLGNTTSTERFLAGVPAGWKVGDKTGAGSYGSTNDVGVLWPPAGAPIVLSVYLTF -PQKDAKGRNDVIASATRIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2B8I2G5_BACAN --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVQKRN -ILTEWMKGNATGDKLIRAGVPTNWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DDNGATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B4AFA1C ------DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. MHM7A TaxID=2583233 RepID=A0A5R9NNT0_9RHIZ ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKAPAAGFVLARVD -KGDEKLDRRVTYGRDKLVDYSPLSEKHAGVDMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASSTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVSKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI00064FEB97 ---DLDETFATIESDYDARVGVYAIDTGSDQTI-EYRSEERFAFASTYKALAAALVLKQNS ---MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGDLLTDDKRE -LLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH -DTEDAEYDDALIAEVAEATLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B43A680 -----NNSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---TEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVNPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWIEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium phaseoli Ch24-10 TaxID=1128399 RepID=A0A0M3GLP2_9RHIZ ---NVERRLAELEKRTGGRLGVSVLDTQTSITF-GYRGSEAFPMCSTFKALAAGFALARVD -KGDESLDRRVTYGKEKLVDYSPTSEKHAGADMTIAELCDAAVTLSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGIKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -KLIAWLVASTTGKERLRAGLLADWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATTPAKDLNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8348B --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -NGYEKALRQLGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAQKSK -ILTEWMKGNATGDKLIRAGVPTDWVVVDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNDf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYLPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium terrae TaxID=2202827 RepID=A0A2U8WQH1_9RHIZ ---DAAAKLAQLERRDGGRLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD -KGQDDLDRRIAYGRDALLSYAPVTSKNVETGMTLAELCAAAVVWSDNTAANLMLDTMGGP -EGITTFARAHGDTVTRLDRTEPTLNTAIPGDVRDTTSPAAMVGLLDNVLLGNALSAGSRA -RLTGWMHESPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEVGRLIAR-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. NFR17 TaxID=1566260 RepID=A0A329ALZ8_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEIGKIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=A0A419ZZV6_9BURK ---AIRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD -HGQENLERRVVFSNSDLVPYSPATSQHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -VALTAFARCIGDGITRLDRNEPTLNAATPGDPRDTTTPNAMLGNLRELLLGERLSASSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVAVYLTE -TSGDAARCNAAIANVGALVA--- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax citrulli TaxID=80869 RepID=A0A481SPD1_ACIAI ----FARAVQEVEASVGGRLGVALLDMATGRQD-AHRGDERFPLCSTFKLLLAAHVLRRVD -QGHERLDRRISYRKSDLVEYSPATERHADGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LELTAWLRSLGDTQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -RMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDAGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAAIARVGTLAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00059D4CD3 --qATHKEFSQLEKKFDARLGLYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I6ZG87_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium etli (strain CFN 42 / ATCC 51251) TaxID=347834 RepID=Q2KAW1_RHIEC ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEENLERRVTYGRDKLVDHSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATASVKDLNSIFAEVGKMITE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B4ZZ63_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIA---------- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033A462 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATIAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudomonas TaxID=2583993 RepID=UPI000CD0915F ---ELYKKLAELENSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM -AEPGLLEKHIAYAEADLLSYAPIAKQNLEQGMSIAQLCAATLQYSDNTAANLLIKELGGV -AAVNLFAKGLGDPAFRLDRQEPELNTAIPEDPRDTTTPAAMAASVQKVVLGDALATAQRE -QLATWLKGNTTGDASIRAGTPTGWIVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ -HQKDAEARRDVLASATRLVMAH- ->[subseq from] Beta-lactamase n=1 Tax=Legionella erythra TaxID=448 RepID=A0A0W0TKI6_LEGER ---SLQQKLAALEASNGGRLGIAAINQANGMVI-QYHARQRFPLCSTSKAISVAALLRKSM -NDKTLLHEKIHYNKQDLVVHSPETEKHLADGMTLAELSEATITLSDNTALNLILKKLGGP -QAITAFARSIGDNEFRLDRFEPELNTAIPGDARDTTTPKAMALSLQKLITTDTLASPERQ -LLITWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTSNDIGVIWPPHCQPVTLVVYFTQ -PKVDARPNNEVIAAATRIVISAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AF3DCF ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011DC87D7 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQGMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B4XCQ7_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q2XT35_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALLAGWFIADKSGAGERGSLGIIEALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF9_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNAAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDEHDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00063E91CD ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGKLTLAQQVKIRASDMLEHAPVTERHVGESLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGETCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C9B153D ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALI--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) TaxID=391038 RepID=B2JHB5_PARP8 ---ALDKRFAQIEAETGGRLGVAILDTANGQLQ-GWRARERFPMCSTFKFLLASAVLMRKD -QGKEQLGRRIVYAKDAVVANSPVSGPRAGGDMTVSELCEAALTRSDNTAANLLLESIGGP -PALTVFARGIGDGVTRLDRNEPTLNEAIEGDPRDTTTPAAMIADMRAMLLGEHLSAASRQ -HLTVWLVANKTGDTRLRAGLPPDWRVGDKTGTGERGTSNDIAIVWPAGRPPVLVAVYLTG -ATTSAAQRDAAIAKVGALVA--- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium TaxID=379 RepID=A0A4R0B1Y1_RHILV --dNIQKRLAALEKRTGGRLGVSVLDTDTSISF-NYRGSEAFPMCSTFKALAAGFVLARAD -KGEESLDRRVTYGKDKLVDYSPLSEKHAGADMTVAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLSESSAD -RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVATVYIAE -ASVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_2_54_15_9cls TaxID=1805418 RepID=A0A1Q6WYY9_9BACT ---DAADQIAAIEARLGGRIGVAGLDTGNGKRI-DYRAEERFPLCSTFKFLAAAAVLKRVD -EKKDKLDRFVSYDAKDILEYAPVTKAHLGNGMTLGALCAAAIEQSDNTGGNLLLEAIGGP -VGLTNFARDLGDRMTRLDRKEPELNSAIPGDDRDTTTPASMLGDIRQLLVGNTLSASSRQ -QLQEWLQANETGAAMIRAGIPTNWIVGDKTGRGANGATNDVAIVHPPDRAPIVLAIYCVG -STASANDRAAAVAEAAKVVAESf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDC0BD8 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGAEKLDRRITYGKDKVVTYSPETEKHAGGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAAKGDPRDTTTPDAMLDSIGLLTLGNTLSDTSRE -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVATFVAE -ATAPAKDVEAVFAEIGKIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BGI3_9BACT ---DVADRIAAIEGRIGCRIGVAALDTGNRKRL-DYRADERFPMCSTFKFLAAAAVLKRVD -EKQEKLERFVPYDAKEILEYAPVTKEHLKDGMTLGALCEAAIEQSDNTAGNLLLDAIGGP -AGLTNFARDLGDRITRLDRKEPDLNSAIPGDERDTTTPGSMLGEMTRLLTGDVLSQLSRR -QLEDWLQGNKTGAAMIRAGIPANWIIGDKTGRGANGATNDIAIMHPPGRAPILLAIYSVG -STATADDRAAAIAEAAKIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL18I3N2 TaxID=1938799 RepID=A0A2T0L7G1_9BURK ---AIRRRLAEIEAASGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD -RGEENLQRRVVFSQSDVVSNSPATGKHARELMSVAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARSLGDGVTRLDRIEPTLNEGTPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTG -TDGDAARSNAAIADVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBE0FB --dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLAAGMVLARVD -GGDENLERRVTYDQEKIVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLDSLGGP -EALTKWLRSIGDTSSRLDRIETELNEAKKDDPRDTTTPDAMLHTLGNLALGTVLSEPSRQ -QLIDWMTANTTGAARLRAGLPEEWKVGDKTGTGSNGSAADIAIIWPEESSPILVAVYVAE -ANAPVSELNDVFAEVAKLAA--- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella sp. K-Nf6 TaxID=2054595 RepID=UPI000C2898B9 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSDKHLVDGMTIGELCAAAITMSDNSAGNLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGNAERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D0195C0 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---KEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000CDB5715 -----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEEMGDDVTNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDNLIAEATKEVIK-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=Q2YHY3_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD078E -hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK -EEKEATYDNQLIAEAAEMIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003E2CB53 --dNVEKRLAALEKRTGGRLGVSVLDTETSISF-NYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPFSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTSPDAMLDTLGNLTLGSILTEASCD -RLIAWLVASTTGGERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPVKDLNPVFAEVGKMIVE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E2DC9C4 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDHWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=UPI0009D72648 ----TAPALARIEAQLGGRLGVAALDTANGARI-GHRAGERFAMCSTFKSLLAACVLARVD -QGQLTLDRRIAYRESDLLEHAPVARARLAEGLTVEELCAAAVEVSDNTAANLLLAQIGGP -AGLTAYLRGLGDQVTRLDRDEPALNTNLPGDPRDTSTPDAMTDTYRSLLVGDALREASRA -RLKAWMVRATTGLARLRAGLPRDWVVGDKTGTGENGIANDVAVAWPPSRAPIVVACFVEA -PSASVDARNAAHAEVARLVAAAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0008F58539 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNDVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDAEYDNALIAEAAKVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium aethiopicum TaxID=1138170 RepID=A0A1C3Y8T1_9RHIZ ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD -KGDEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -KLIAWLVASTTGGERLRASLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATVPAKELNPIFAEIGKMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B51C55 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00103F8875 ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFSMCSTFKALAAAFVLARAD -KGEENLDRPVSYGKDRLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0009A9C9D9 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -PGLTAFIRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLA---- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A495H0X1_9BURK ---AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD -HGQEDLERRVVFSKSDLVPYSPATSQHTRERMSVADLCKAALTLSDNTAANLLLASFGGP -AALTAFARSIGDGITRLDRNEPTLNEATPGDPRDTTTPSAMLGNLRELLLGERLSSLSRA -QLLAWLAANRTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE -TSGDAARCNAAIASVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF2C7B1 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia ignorata TaxID=145285 RepID=UPI00082D37C6 ------TQFAALESKYTARLGLSVTDTGTGATV-AYRADERFPIASTFKGLACGALLQAHP -LSTGYFDQVIHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP -AGFTAFLRTLGDNVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAEPERT -QLADWLKANTTGGKRIKAGLPTDWTVGDKTGSPAYGSALDVAIAWPPNRPPLVLAVLSTK -SEQDAEPSNELLAEATKAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter marginalis TaxID=1774971 RepID=A0A1E3W8X7_9RHIZ --kSLEQTFAAIEAKVGGRLGVAAYDTGSGLKA-AWRGDERFPLCSTFKWLAGAAILARVD -QGKETLKRKVPIRAEEIVTYSPATEKHVGETMPLEQICEAAIALSDNTAGNLMLAALGGP -EGFNAYVRSLGDGVTHLDRIEPALNEAAPEDPRDTTTPLAMIADLDAALVGDALSRASRN -KLTAWLIGNETGDARLRAGLPENWRVGDKTGTCNARTANDVAIAWPPSGKPVLIAVYLAE -SDVSPEAQNKAIADVARAVAT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ0_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLFRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTAIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDGRDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D624_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000C77DB24 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5S4Z009_9BACI ---DLDETFATIESEYDARVGVYAIDTGSDQTI-DYRSEERFAFASTYKALAAALVLKQNT ---MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAIRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALAMSLQGFAVGDLLTDDKRE -RLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH -DTEDAEYDDALIAEVAEATLN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum bv. trifolii WSM1689 TaxID=754523 RepID=W0IAJ4_RHILT ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLDRPVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPADRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000E4EE96E ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -LLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI07_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A0B5S764_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005CDCEDA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMGTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HG88_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSPNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2CC11A ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWEMALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG3_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLPLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF686AA ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKNS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001034683A ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQHDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-46 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5B8WEV9_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELEPNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A4P2QKS1_SORCE ----AAPALARIEAQLGGRVGVAALDTATGARV-GHRAAERFAMCSTFKALLAACVLARVD -QGQLRLDHRVTYRESDLLEHAPVTRARVAEGLTVEDLCAAVIEISDNTAANLLLAQIGGP -AGLTAYLRGLGDEVTRLDRNEPALNENVPGDPRDTTTPDAMTDTARAILIGDALQRASRE -RLASWMVRSTTGLARLRAGLPKDWIVGDKTGTGM-GIANDVAVAWRPSRAPIVIACFVDA -PSASADARNAAHADVARVVAEAf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Q4LKB6_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKAIAAGVLLQKNS ---TEKLNEVITYTKEDLVDYSPVTEKHVGTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDMVTLSDRFETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALSDDKRN -ILTDWMRGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Prosthecobacter debontii TaxID=48467 RepID=A0A1T4YQW7_9BACT ---SAHRQLAELEFESQGRLGIAAWTASSRRSV-RYRPNERFPFCSTFKFLAAAAILKRTE -QDPTELDRHIRYSKQDLVSYSPITEKQAGRSMSLAQLCAAALQYSDNTAGNLLIKELGGT -QAMTAFARSIGDSTFRLDRWETELNTAIPGDVRDITSPAAMAHDLQRLLLGHGLSPQQRN -QLSTWMRGNTTGAARIRAAVPSDWEVADKTGSGDYGTTNDIGILFPPNQSPIILAIYFTQ -KTSQAPMRNDIIAAATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Q9HYG7_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000BB85D27 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVXGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQI----------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWVEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC8266 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQIV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIVWMKRNTTGDKLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Trinickia caryophylli TaxID=28094 RepID=A0A1X7FSF0_TRICW ---DAAQALAALERISGGRLGLCAIDTARGATL-GYRASERFPFCSTFKLMLAATVLARSV -EEPALLEHRIRYARTDLVNYSPETGKHVDDGMTVSELCRVTVQWSDNTAANLLIDLLGGS -QAVTAYARGIGDREFRLDRRETTLNTAIPGDLRDTTTPAAMAQSTRSLVLGSALPAPQQA -RLRDWLLGCKTGDRRIRAAVPAGWQVGDKTGTGDYGTANDVGVLWPPAEKPLVLAIYHTH -TDSAAKARDDVIASAARIAIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0006CAD317 ----LRAQWAEIERGTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Phytobacter palmae TaxID=1855371 RepID=UPI0008ECB3FF ---VTQETVKKAEDQLNARVGYAEVALANGQILgSYRPQERFPMLSTFKVLLCGAILSRVD -AGQEQLARRIRYRQQDLVEYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDQVTRLDRWETALNEALPGDERDTTTPEAMAQILRQLLTGKILTPASQK -QLIAWMEADKVGGPLIRSVLPSGWYIADKTGAGGRGSRGIVAALGPDGKPTRIVVIYITG -TQATMDERNKKIADIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. DE0042 TaxID=2584950 RepID=UPI0011AA81B5 ---TVNHSFSKLEKEFDVKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPEHFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPRGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK1 TaxID=1628193 RepID=A0A0J6K8B5_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ -AKPGLLDKRIRYSKTTLPNWSPLTTQHQANGMTVAELSAATVQYSDNGAANLLLKEINGP -AALTAFMRSIGDTTFRLDRLEPELNSAIPGDPRDTSTPKAVAESMQKLALGKALAAPQRQ -QLADWLKGNTTGKARIRAAVPDGWEVGDKTGTCGYGTANDYAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEE17E0 ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLVQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLAAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA86C5 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas mucosa TaxID=207340 RepID=A0A4Y1MSQ5_9PROT ------AVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD -AGQARLDQRIRYGREKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP -AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA -HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGAGERGTNNDAGLLWPPGEAPILVAAYSTG -STAPSTERDAALAEVAAAIVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q84H47_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQQIAGIGAAL---- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A387A347_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B5PYY6_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF53E98 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. DHF22 TaxID=2571748 RepID=UPI0013172108 --sALEQQLAAIESQAGGRLGVAILDTANGRVE-GWRLHERFPMCSTFKVLLASAVLTRKD -RGEEDLARKIAYTQAQVVSYSPVSGPRAGSDMTVAELCEAALTRSDNTAANLLLDSLGGP -AAITAFARGLGDPHTRLDRNETTLNEALEHDPRDTTTPAAYIADMRELLLGERLTQASRE -QLIAWLVANQTGDARLRAGLPKDWRVGDKTGTGDRGTANDVAIVWPPNRAPLLVTAYLTG -ALATPAQRDATLAKVGALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia ignorata TaxID=145285 RepID=A0A4R6PV82_9NOCA ------TQFAALESKYTARLGLSVTDTGTGATV-AYRADERFPIASTFKGLACGALLQAHP -LSTGYFDQVIHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP -AGFTAFLRTLGDNVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAEPERT -QLADWLKANTTGGKRIKAGLPTDWTVGDKTGSPAYGSALDVAIAWPPNRPPLVLAVLSTK -SEQDAEPSNELLAEATKAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDC002 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETTLNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb209 TaxID=1848605 RepID=A0A2S8UU15_9BACI ------HSFVQLEKEYDAKLGIYALDTGTSQTV-TYRSDERFAYASTHKVLAVGALLQKNS ---IEALDQRIKYTSEDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQTYALGDILSTEKRN -FLIDLMKRNTTGDNLIRAGVPREWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLVILSNH -AKEDAKHDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2A7Z4F9_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7IXD9_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKYVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIITILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase CRH-1 n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A5S9EKA3_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ -DKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CED9528 ----LRAQWAEIERRTGGRLGISLLDSATGRHL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI26_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007CBEB2E ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAELPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00099508CE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ8_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIRYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIITALGPDSKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=2 Tax=Viridibacillus sp. OK051 TaxID=1884360 RepID=A0A2N0F505_9BACL ---TTMEKFEQLEKEYDARLGVYAIDTGTKKTV-EFREDERFAYTSTFKALAAGAVLQQNS ---IEELNKIVTYTSDDLVTYSPITEKYVDTGMTLKEISEAAIRYSDNTAGNLLFKELGGP -EGFETSLKKLGDQVTNAERIETGLNEAVPGETRDTSTPKALANDLQAYTLGDVLTHEKQT -MLVDWLKRNTTGDNLIRAGVPKGWEVGDKTGGGGYGTRNDIAIVWPPNREPIVLAILSSR -DKQDATYNDELIAQATKVVMNVf ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A486UH21_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora siamensis TaxID=299152 RepID=A0A1C5I8Q1_9ACTN -----EHEFRQLEERFDARLGVYAIDTGTGRTV-QYRADDRFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITGRHVDEGMTLRAIADAAVRYSDNTAGNLMLRQLGGP -QKFEKELREVGDKVTDPARWETALNEARPGDRRDTSTPRAMAGSLRAYAVGDALEPADRD -ILTGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRVPIVLAVLSSR -DEKDADYDNALIAEATKVALAGw ->[subseq from] class A beta-lactamase LEN-51 n=1 Tax=Klebsiella sp. P1CD1 TaxID=2267618 RepID=UPI000F4DF0CB ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Eumeta variegata TaxID=151549 RepID=A0A4C1YE18_EUMVA --qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPVTRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRNEPGLNTAIPGDDRDTTTPSAMAESLKKVVLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -HDKDAATRKDVLASAAKLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00141B6701 ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGELTLAQRVKIRASDMVEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPDDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDSCLRAGLSRGWKIGDKTGNNGTDTRNDIAIVWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0013FDB62B ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTPPSLSARSQQ -QLLQWMVDDRVAGPLIRAELPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAVIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B84D1BE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter nanhaiticus D15-8W TaxID=626887 RepID=N6VZT2_9ALTE ---AFTHAVADLESAKGGRLGVAVWDTETGDRF-GHRADERFAMTSTFKWVLVAAVLSRVD -AGEETLDRQVRYDDSDILSYAPIAKQHLPEGMTVAELSDAAIRYSDNTAANLLLETLGGP -EGLTDYMRTLGDEVSRLDRYEPELNANLPGDERDTTTPSAMLNAMQAALVGDALSPASKK -RLHDWLIRNTTGDAKLRAGLDPDWTVGDKTGSGARGASNDVAIVWHSDGGPILIAVYYSD -SALSNEAQSAVHAEVGRLVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD107 TaxID=1053229 RepID=J8JV93_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas lutea TaxID=243924 RepID=UPI0009DFFE20 --qTIAQRLVELERRHGGRLGVAILNTASQRLI-DHRGNERFALCSTFKCLAAACVLARVD -QQQEALSRRIVYGREQLVPYSPTTESHAGGQLSVGSLCEAALTLSDNTAANLLLDSIGGP -QALTQWLRSIGDTQTRLDRREPELNENRPGDERDTTTPMALVQTLNTLILGDVLSLPSRD -QLTAWLVNNQTGDKKLRAGLPRGWRVGDKTGSGANNASNDVAILWPGDRAPVLVSVYYTG -SIAGGDQINALMAEIGSLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar navarrensis TaxID=339658 RepID=A0A243AR07_BACTU ------DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTKKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2C231F ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNGAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLLRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum brasilense TaxID=192 RepID=A0A2W5TF38_AZOBR ----LPAAFAGIERRVGGRLGVAVLDTATGQRA-GYRETERFPLTSTFKLLAAAAVLARAD -AGQARLEQRIRYGREKLVTYSPETEKHAGEEMTLAAICEAAITLSDNTAGNLMLEQLGGP -AGLTAWLRSIGDEVTRLDRWETALNEAKPGDPRDTTSPAAMLASLQRVTLGEALSDKAQA -HLSGWLRASRTGDKRLRAGLPAGWQAGEKTGAGERGTNNDTGLLWPPGGAPILVAAYSTG -STAPGPERDAALAEVATAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHX8_KLEPN ------EQIKISESQLAGRVGYIEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas lutea TaxID=243924 RepID=A0A098T0P8_9PSED --qTIAQRLVELERRHGGRLGVAILNTASQRLI-DHRGNERFALCSTFKCLAAACVLARVD -QQQEALSRRIVYGREQLVPYSPTTESHAGGQLSVGSLCEAALTLSDNTAANLLLDSIGGP -QALTQWLRSIGDTQTRLDRREPELNENRPGDERDTTTPMALVQTLNTLILGDVLSLPSRD -QLTAWLVNNQTGDKKLRAGLPRGWRVGDKTGSGANNASNDVAILWPGDRAPVLVSVYYTG -SIAGGDQINALMAEIGSLAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI000BF5DCD4 --qATHKEFSQLEKKFDARLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNA ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMRDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTNWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAAAAKVIVN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI00119F2106 --qATYKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVINYTKEDLVDYSPVTEKHVDTGMILGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKEFTVGNALPDHKRN -ILTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKDAPYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus gaemokensis TaxID=574375 RepID=UPI00079B2846 ---ATHREFVQLEQKFDARIGVYAIDTGTNRTV-AYRPNERFAYASTYKALAAGAVLQQNS ---IDKLDEVITYTKDDLVTYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNLLFNKLDGP -NGFEKALKQIGDRVTKADRYETDLNEATPGDIRDTSTAKALATDLKAFTVDDVLSADKRK -ILTDWMRGNTTGDQLIRAGVPKDWEVGDKSGAASYGTRNDIAIVWPPNREPIIIAILSSR -DTQDATYNNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A150Q6J4_SORCE ----TAPALARIEAQLGGRLGVAALDTANGARI-GHRAGERFAMCSTFKSLLAACVLARVD -QGQLTLDRRIAYRESDLLEHAPVARARLAEGLTVEELCAAAVEVSDNTAANLLLAQIGGP -AGLTAYLRGLGDQVTRLDRDEPALNTNLPGDPRDTSTPDAMTDTYRSLLVGDALREASRA -RLKAWMVRATTGLARLRAGLPRDWVVGDKTGTGENGIANDVAVAWPPSRAPIVVACFVEA -PSASVDARNAAHAEVARLVAAAf ->[subseq from] Beta-lactamase n=2 Tax=Stigmatella aurantiaca TaxID=41 RepID=A0A1H8D7F7_STIAU -----RSRLAELERRHGGTLGVAVLDTASGELV-LHRADERFPLCSTFKFLAAARVLARVD -RGEEQLGRRIVFSEADLVSYSPVTKEHVGGEMTLEAICEAAITLSDNTAGNLLLDSFGGP -AALTRYVRTLGDKKTRLDRRETELNEAKPGDPRDTTTPAAMLQDMQRLLVGDALSASSRE -RLVAWLTASKTGAKRLRAGVPPDWRAGDKTGTSGNGVVSDIAIFWPPDRAPLLVSAYYRG -PEG---TGDAVLEAVGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 10 TaxID=1101191 RepID=UPI000488CC78 --qDLADRFVHIEEASGGRLGIGLLDTGSGAQA-AHRGAERFPLCSTFKILAAGAVLARVD -RGEDSFDRRLRYEPREVVPYSPLSGPRAGGEMTIAELCEAAVTVSDNTAANLLLGTMGGP -AGLTARIRAFGDEASRLDRTEPDLNEAAPGDPRDTTTPLAMAETLRRLVLADALSPASRA -LLTAWLVGCRTGDARLRAGLPKDWRIGDKTGSGENDTANDVAVIWPARRPPLVLTVYLTG -ARTSPEARSATIASVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caffeinilytica TaxID=1761016 RepID=A0A346B6H1_9BURK ---AMRQRLAQIEAESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD -RGQEALERRVVFSKGDLVPYSPATSRHTRERMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFVRSIGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTAYLTE -ASGDTARCNAAIAKVGALVA--- ->[subseq from] class A beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=UPI00099F259F ---DVRRRLRELEKSYPGRIGVHALHTGTGATV-GYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDVLIRYGRDDLVEHSPRTELHLETGMTVRELCDATLTYSDNAAANLLMRRIGGP -SGITEFARSIGDAHTRLDRWETDLNTNIPGDRRDTTTPAAMTGNLRGLVLGDALHPLDRD -QLIRWLLENTTGDKRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKRAPLVISVYTTR -RDPDTPGEDRIAEDITRIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Phenylobacterium TaxID=2640670 RepID=UPI00083AA7D7 ---SADAALADLERRHGGRLGVVIWRPADGLRI-ARRADERFAMCSTFKTLAAAAVLARVD -RGREDLARRIVFGKDQVVTYSPVTGPRVGGEMTLSEICAAAIRYSDNTAGNLLLDSLGGP -AGLTRFARGLGDGITRLDRYETLLNEATPGDPRDTTSPEAMARNLRKLLLGPALSPESRR -RLSQWMASNTTGDARIRRGIPMGWVVMDKTGAGENGANNDVAVVLPPSGQPAIVTVYYAE -SQATGAQRNAVIADVARVAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5410A ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKIVTYSPETEKHADGDMTVAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEIGKIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai B8W22 TaxID=1358420 RepID=A0A1G7DEL2_9BACI -----KHHFVKLEDKFDARLGVFALDTGTNQTV-TYRADERFIYASTSKALAVGTLLQQKT ---IEDLNQRITYTQDDLVNYNPITEEHVDTGMTLKELCDATLRYSDNTAMNLILKQIGGP -NGLEKALRDVGDNVTMPERFEPELNEVKPGETHDTSTPRALATSLQSFTLGDALPVEKRG -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPPKGDPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] Beta-lactamase n=1 Tax=Bacillus tropicus TaxID=2026188 RepID=A0A4Y6FAD3_9BACI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTA-NLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Ensifer adhaerens TaxID=106592 RepID=A0A0L8BQ93_ENSAD ---SVDARLAELEKRTGGRLGVSVLDMETNISF-GCREDERFAMCSSFKTLAAGFILARAD -QGAEKLDRRIVVAQKDIIAHSPVTEKHIGGKMTIAELCAATMTTSDNAAANLLLERFGGP -PALTAWLRTIGDETTRLDRNEPGLNEAQKGDPRDTTTPAAMLETLGKLAFGPALTETSRK -LLVEWMVANTTGDLRIRAGLPKGWRVGDKTGTNGNGAASDIAIVWPEGRGPLLLAVYIAE -ATAPLAELNAVFADVGRMAAE-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_1_20CM_3_54_17 TaxID=1805405 RepID=A0A1Q7UYU7_9BACT ---DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD -EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -SGLTNFVRSLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDALSEASRR -QLEDWLQRNETVGPMIRAGVPKNWILGDKTGRGSNGATNDIAIMRPPGRAPILLAIYSVG -STATPNDRAAAVAEVTKIVVESf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar navarrensis TaxID=339658 RepID=A0A243A300_BACTU ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009918E22 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. H3(2019) TaxID=2598724 RepID=A0A558F0F2_9PSED ---ELYKKLAELENSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM -AEPGLLEKHIAYAEADLLSYAPIAKQNLKQGMSVAQLCAATLQYSDNTAANLLIKELGGV -AAVNLFAKGLGDPAFRLDRREPELNTAIPDDPRDTTTPAAMAASVQKVVLGDALATAQRE -QLATWLKGNTTGDASIRAGTPAGWIVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ -YQKDAEARRDVLATATRLVMAH- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFEA18A -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---ANKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0004D6AF5B ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTALLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A broad-spectrum beta-lactamase OKP-B-45 n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000651787B ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-35 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2U9IB43_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELEPNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI0011A77F71 ---SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA -SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV -ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE -QLAVWLKGNTTGGETIRAGAPAEWVVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ -REKDAKPRRDVLAAATKILLSH- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RQ59_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLAGVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI00144230F5 ---NIEHRLADLEKRTGGRLGVSVLDTETSISF-GYRGSETFPMCSTFKALAAAFVLARAD -KGEENIYRRVSYGKDKLVDYSPISEKHAGADMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPNAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A679GZL5_9BACI ------DSFVKLEKEFDAKLGIYVLDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD021 TaxID=1053224 RepID=R8HNN6_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T942_9BACT ------------EDQLGARVGYIELDLDSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLRNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000C7A2B48 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHISGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. GW458P TaxID=1981504 RepID=UPI000A31ED6A ---AAQTQLAALEQVAGGRLGVAAWRQGSEQRV-AYRADERFPLCSTFKAMLAGAVLARSA -SQPGLLEQQVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDSWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPGGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. L43 TaxID=2035452 RepID=A0A2A6HXG7_9RHIZ --dNIQRRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARAD -KGEEKLDRRVSYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -VALTDWLRSIGDGTTRLDRTEPTLNEGKKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVASTTGGERLRAGLPAEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPVFAEVGRMIIE-- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus sp. LC231 TaxID=1120679 RepID=A0A1S2F1S2_9BACL -----------------IELYVGVQDLSGGGKI-QAGSSNVYYAASTIKMAIVTALMQDIE -AGKYALEQTVQVKPEQVVGGAGSLKDKFPQEITIERLAGLMITQSDNTATNALIDLL-GF -ERINTLIDEQGFETMQLGRKMMTPAKS--PAADNYVNGEELLTLLERIYAGEIVSAQSRD -QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-VAVTVLTKV -TKKAQELGNPVVQRAAKAVYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus sp. LC231 TaxID=1120679 RepID=A0A1S2F1S2_9BACL ------------AEEKGIRVSVGLKDLSDDREL-LLGSRQSYMPASTIKMALVSALMKEVD -AGRLTLEQKVKVEQEDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL -NKVQALMDELGLDVMHLGRKMFAAA--PTPEQDNYINAEDLVHLLANIHSGEFLSDNSRD -QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLLPGRE-IAISVLTEV -TTEAQAIGNPVVQEIAKAVYE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000992529E ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-TYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000B1CC87E -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVPAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. ARR65 TaxID=1040989 RepID=UPI0004631E50 ----LPDAFAEAEADSGGRLGVAVLDSAAGAAI-GHRENEHFPMCSTFKVLAVAAVLSRID -AGKEQITRRIRIAPGDLLAYAPVTQQHVGADMSVADLCEAALTLSDNTAANLLLASLGGP -SAVTQYARALGDDLTRLDRVEPDLNTADAGDLRDTTTPLAMARNLTALATGTALSPASRE -LLINWLIGCKTGDAKLRAGLPKTWRVGDKTGSGAHGTSNDVAVIWPPGRAPLIVTMYLTE -TALPDDKRNATFAAIGREI---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4R1EFZ5_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---IEKLNEVVTYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRLETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDQKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A5R8P8B6_9NOCA ------PRFAALETTTAARLGVFAVDTGSERTV-AHRADERFPMASTFKGLACGALLREHP -LSTGYFDQVIHFSAEELVEYSPVTETRVESGMTVAELCDAAITVSDNTAGNQLLKLLGGP -QGFTAFLRSLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA -QLTAWLVANTTGDTRIRAGLPEDWTVGDKTGSPAYGSALDVAVTWPPGRAPIVIAVLSTK -SEQDAEPDNRLVADATRTVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEE8935 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIHASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQLASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax konjaci TaxID=32040 RepID=A0A1I1SZQ7_9BURK ----LQEALQRIEASVGGRLGVGLLDVEAGRQA-AYRGDELFPLCSTFKLLLAAQVLRRVD -QGQERLDRRITYRKVDLVDYSPATAPHADGEMTVAQLCEAAVTLSDNTAANLLLDSQGGP -QGLTAWLRSLGDAHTRLDRKEPELNDVPEGEVRDTTTPRAMARTIWAITHGEALSAAGRR -QITDWLVGNRTGDKRLRAGMPQGWRIGEKTGTGPRGTSNDAGLFWPPGRKPVMVSSYLTG -SPAEPARRDEAIAQVGALAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000F8DF1C0 ----LRAQWAEIEHRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLTAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1J9V3Q1_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEMAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. 602-1 TaxID=2492472 RepID=A0A3R8MA35_9CAUL ---ALSSRINELERRSGGRLGVAVLDTQDGRRF-AWRGDERFRMCSTFKMPLAAAILRRVD -QGRERLDRRVTYGREVLMGNSPAVEKHLAQGMTIGELCAATITLSDNAAANLLLDALGAP -TDLTRFLRALGDQTTRCDRREPELNTGAPDDPRDTTTPAAIVETWKTLLTTDALSTASRK -RLTAWVVANRTGDKRLRAGLPRGWKVGDKTGNNGQDQTNDIAVIWPPGRKPLFVSAFHDQ -GSADDDVRSAVLADVARAVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=A0A386V1Q2_9BACI ----TYKDFSQLEKKFDARLGVYAIDTGTNQKI-SYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYKKEDLVDYSPVTEKHVDTGMTIGQIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=Q4L1Z9_RAOOR -heATVTTVKQAESQLQGRVGYAELDLASGQLLsGYCAGERFPMMSTFKVLLCGAVLSRVD -TGEEQLDRRIHYRQQDLVEYSPVTEKHLADGLTVGELCAAAITLSDNTAANLLLTTLGGP -QGLTTFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPEAMARTLRNLLTGRVLSPASQQ -QLQRWMVEDKVAGPLLRSALPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTA -TPASMDERNKQIAAIGETLVRHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. MWU14-2602 TaxID=2073169 RepID=A0A2S5DA09_9NEIS -------KFAKLEKDFGGSIGVYAIDAGSGATL-SYRADERFPLCSSFKGFLAAAVLAQEQ -KQAGLLDKRVSYGKEALISWSPITEKHQAKGMTVAGLSAATVQYSDNAAANILLKELGGP -AQLTAFMRSIGDQTFRLDRREPELNTAIPGDARDTSSPRAVAESLRKLTLGSALAAPQRQ -QLIDWLKGNTTGDKRIRAAVPAGWAVGDKTGTCGYGTANDYAVIWPTGRAPVVLAVYTKA -QDKALKSSDAAIAAAAKAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis MBA4 TaxID=1323664 RepID=A0A0P0RAH1_9BURK ---ALERQLAEIEARTGGRLGVAILDTAGAKQQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMAVGELCEAAITRSDNTAANLLLDSIGGP -AALTAFARSIGDRITRLDRNEPTLNEATQADPRDTTTPAAMLADLRTLLLGEHLSAASRE -QLTAWLAANKTGDTRLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATASATQRDAAIAQVGTLVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C3D872_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGVPTDWEVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Aureimonas ureilytica TaxID=401562 RepID=A0A175RTX0_9RHIZ ---DLDALWAEIESRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD -AGQENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALTQSDNTAGNVLIDLLGGP -EGVTRTARGFGDESFRLDRRETALNEAKPGDPRDTTSPAAMTKTLHALLFGKALKPDSRR -QLADWMVANRTGDAKLRAGLPKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILISLYLTE -TKASFDERNAAFAEIGRAL---- ->[subseq from] Mutant KPC family beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A6B7HYA8_ENTCL -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARHTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5NIJ0_9BACI --nKVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKNVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLRELGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDSLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPTVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI001034D81C ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSACSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia insulsa TaxID=1441714 RepID=A0A2T1ASV5_9BURK --eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLTAGFVLMRVD -HGQETLERRVVFSKGDLERYSPATSRHTRELMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGDLRELLLGERLSAPSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGSGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARCNAAIADVGEVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9YNH7_BACMY -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTRQDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00099264CE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKKATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. WMMC415 TaxID=2675222 RepID=UPI0012B4835F -----DREFRRLEERFDARLGVYAIDTGTGRTV-GYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITERHVADGMTLRAIADAAVRYSDNTAGNLLLRRLGGP -QKFEKELREVGDKVTDPARYETALNEARPGDRRDTSTARAMAQDLRAYAVGDALEPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DQKDAGYDNALIARAAEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio sp. (strain FO-BEG1) TaxID=911045 RepID=G8PND4_PSEUV ---ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ETRADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAFSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA -QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPKTGKPYLTAVYMTG -SDADFKKRNAVIAEIGKAIVE-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00133002E8 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD2755 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sullae TaxID=50338 RepID=A0A2N0D2D8_RHISU --dDIERRLAGLEKRTGGRLGVSVIDTETKVTL-GYRETERFPMCSTFKVLASAMVLSRVD -KGEENLERRVIYHESKLVSYSPETEKHVGGEMSVAELCKAAITLSDNTAGNLLLESFGGP -EALTKWLRSIGDRSTRLDRWETALNEGKKDDPRDTTTPDAMLDTLGNVALGSVLSEPSRN -TLIGWMMANTTGGARLRAGLPGSWKVGDKTGTGNNGTAADIAITWPKGRGPILVTTYIAE -ATAPVKELNPVFAEVAKIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Cobetia sp. L2A1 TaxID=2686360 RepID=UPI00131E1D0B -----QDSVRTIEQEVDARMGVAVLDTADGTRF-TYRGDERFPMSSTFKALACGSMLALVD -AEQESLQRKVKIKPEAVVTYSPVTETQTEGDLTLSELCNAAVTISDNTAGNLILDAVGGP -AGLTAYLRSLGDDTTRLDRTETSLNEATPGDVRDTTTPNAMVTTLQKLLLGDALSEDSRI -KLQSWLLANTTGEGKLRDALPAGWQIGDKTGGGGHGTNNDVAIIWPPGHAPLIVAVYLTE -SDASLAQRNAAIAGIGRLLVT-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. YR213 TaxID=1881027 RepID=A0A1G8FDT2_9BURK ---AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuB1-1 TaxID=1053207 RepID=J9C608_BACCE -----NDSFANLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF35914 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALVVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pragia sp. CF-509 TaxID=2589859 RepID=UPI00112C3AAC ----IQQNLADLEKSTGGRLGVVLINTADNSQI-IYRGDERFPMCSTSKMMVVAGVLKQSE -SQKGLLDQQVDIKKKDLVSHSPIAEKRLNNKMSLAELSAATLKYSDNAAMNKLIEQLGGP -QKATAFARSIGDQSFRLDRTEPTLNTAIPGDKRDTTTPLAMAVSLQKLTLGEALAAPQRA -QLVEWLKGNTTGAASIRAGLPAEWVVGDKTGSGSYGTTNDIAVIWPKDKAPLILVTYFTQ -NEKNAKSRREVLASAAKIV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYPPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHATRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. URHA0054 TaxID=1298859 RepID=UPI0004257CE4 ---AIRARLEEIEAQSGGRLGVSIVDTTSGLHA-GLHADERFPMCSTFKLLAAGAILARVD -RGEEDLQRRIVYPESELVPYSPATSKHTRERMSIAELCKAAITLSDNTAANLLLQSFGSP -AALTAFARSLGDGITRLDRNEPTLNEATPGDPRDTTTPNAMLGNMRELLLGERLKSSSRV -QLLAWLAGNETGGARLRAKLPKDWGVGDKTGTGDHGTANDVAIFWPPGRGPVLVAVYLTG -TAGDAARNNAAIANVGALVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis UCMB5033 TaxID=1338518 RepID=S6FQZ7_9BACI ----LNQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAETAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. San01 TaxID=2494256 RepID=A0A3S2YZ26_9ACTN ---DARRRLRELEAGYPGRIGVHALDTGTGACL-AYRADERFAIASTFKVLAAAAVLRRAR -EEPGLLDVLVRYTRDDLVAASPRTTMHLETGMTVRELCDATITYSDNTAGNLLLRRIGGP -SGVTAFARSLGDRETRLDRWETDLNTNLPGDPRDTTTPAAMTADLRALVLGDALHPLDRG -QLTRWLVENTTGDKRIRAGLPPGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVISVYTTR -LDADTPGEDRIAADITRIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1Y6AQI4_BACCE -hqATHKEFSKLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS ---TEKLNDVITYTKDDLVEYSPVTEKYVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNVLPVHKRN -ILIEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Janthinobacterium TaxID=2610881 RepID=A0A2G3KKX9_9BURK ---AAQTQLAALEQVAGGRLGVAAWRQGSEQRV-AYRADERFPLCSTFKAMLAGAVLARSA -SQPGLLEQQVRYEKKELVTYSPITEKHLADGMRVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDSWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPGGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. SA187 TaxID=1914861 RepID=UPI0009345718 ----TLSAVKQAETTLAARVGYAELDLASGKVLnSYRQDERFPMMSTFKVLLCGAVLARVD -AGQEQLNRRLTWQKADLITYSPVTEKHLADGMTVAELCDAAITLSDNTAANLLLSTLGGP -QKLTDFIRKTGDGTTRLDRVEPELNEALPGDVRDTTTPTAMAKTLRQLLTGDTLTAASRQ -QLARWMEEDKVAGPLLRSVLPAGWYIADKTGAGERGSRGIVAALGPDGTPSRIVVIYVTG -SKATMDERNKAIAAIGEAVIKQw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF65F29 ------DSIVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000F5B8FC3 ----LNQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium ecuadorense TaxID=1671795 RepID=UPI0006734470 --dDIEKRLAALEKRTGGRLGVSVLDTQTSISF-NYRGSEAFPMCSTFKALAAGFALARAD -KGQESLDRRVTYGRDKLVDYSPLSEKHAGADMTITELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSILTEASSD -RLIAWLVASTTGGERLRAGLPKEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus proteolyticus TaxID=2026192 RepID=UPI000A03F9C8 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIVEAAVRSSDNTAGNILLNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATTLKAFTVGKALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKEDTYDNQLIAEAAKVVIN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B2JY17_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A0N9WJ97_PSEFL ---ELYKKLAELENSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM -AEPGLLEKHIAYAEADLLSYAPIAKQNLEQGMSIAQLCAATLQYSDNTAANLLIKELGGV -AAVNLFAKGLGDPAFRLDRQEPELNTAIPEDQRDTTTPAAMAASVQKVVLGDALATPQRE -QLVTWLKGNTTGDASIRAGTPTGWIVGDKTGSGDYGTTNDVAVLWPQTGAPVVLAVYFTQ -HQKDAEARRDVLASATRLVMAH- ->[subseq from] Beta-lactamase n=1 Tax=Izhakiella australiensis TaxID=1926881 RepID=A0A1S8YML9_9ENTR --sDLHQQLEALEKQHNGRLGMTLIDTASGHSL-QYRGNERFPMCSTSKALLAAAVLNLSL -RQPDLLERRIHWDKSEKLSWMPVTEKHQDSGMTVSELCQAMIQYSDNLAANLMLKLVGGP -AAVTAQARALGDQVTRLDRTEPTLNSAIPGDERDTTTPLAMARDLQKLAFGSGLPPRERQ -LWIGWLRGNTTGKQSIAAGVPSGWQVGDKTGSGDYGTTNDAALLWPPQRQPLVLTVYFTQ -PEKAAPSNRAVLAESARLTLAAw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00084CD7A2 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. EKM20T TaxID=2708059 RepID=UPI00142E615A ---TLKSQFETLENKSVGRLGVTVVDTSDGSEY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=A0A4R5ZRM4_9NOCA ---HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTYKALAAGALLQHYS ---IDQLDELVTYTSEDIVSYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLKKLGGP -EGFETTLRQIGDNVTQVDRYEPDLNSAVPGDKRDTSTPKSLATSLQAFAVSDFLSTEKRK -ILTDWMRGNTTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAILSSR -YTENATYDNALVAEAAKVAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia guartelaensis TaxID=2546446 RepID=A0A4V2ZWI5_9BURK ---AVEKQLAAIEAQAGGRLGVAMLDTANGHVR-GWRMHERFPMCSTFKVLLASAVLTRKD -HGKEDLARKIVYSTAQVVSYSPVSGPRAGSGMTVAELCEAALTRSDNTAANLLLESIGGP -PAITAFARSIGDPVTRLDRNETTLNEAIPGDPRDTTMPAAMVANLRELLLGERLSAASRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIVWPTGRAPILVTTYLTG -AMASSAQRDAAIARVGV------ ->[subseq from] Beta-lactamase TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00062CAFE3 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMXTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWNPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKXAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A291RJM4_9NOCA ----ATTEFASLETEYGARLGVYAVDTGSGRTV-AHRADERFAYASTLKSLAAGAVLQSVP ---PAGLDERITYTRADLVPNSPVAEQHVDGGMTLRETLDAAVRYSDNTAANLLVAKLGGP -KGLQRRLRDLGDTVTQVDRTEPDLNEATPGDPRDTSTPTAFAADLRRYVLGPVLTDPARA -LLTEMLRANTTGGELIRAGVPAGWVVGDKTGLGSYGSRNDVAVLWPPHAAPIVLVVFTTR -PDKDASYDNALIAKAAAAAVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1S9X099_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB1D15 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGKDKLVAYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SRB_28 TaxID=1969378 RepID=UPI000DC4594F ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WG11_9BACT ----LSDAMAALERRSGGRLGVAVLDTGSGRRF-DWRGNEMFPMCSTFKFLLAAAILKRVD -EGRESLTRRIPVSPGDLIPYAPFAETRVNGTPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFVRSLGDERTRLDRNEPTLNSSIPGDPRDTTTPNAMVHSMDRLMVGDALRPSSRE -QLIGWMVGNKTGDKRLRAGLPRDWRVGDKTGTGN-GSFNDIAIVWPGASPPILIASYVTQ -TPEGFKQGDAIHAEVARAAAGAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1S9TE91_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIADAAEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacillus licheniformis TaxID=1402 RepID=P94458_BACLI --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVVK-- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. (strain FO-BEG1) TaxID=911045 RepID=UPI0002FA5D02 ---ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ETRADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAFSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA -QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPKTGKPYLTAVYMTG -SDADFKKRNAVIAEIGKAIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus pacificus TaxID=2026187 RepID=A0A3P1BPS1_9BACI -hqATHKEFSKLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQYS ---TEKLNDVITYTKDDLVEYSPVTEKYVDTGMKLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNVLPVHKRN -ILIEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=2 Tax=Skermanella aerolata TaxID=393310 RepID=A0A512DMQ9_9PROT ----LSDVMAALERRSGGRLGVAMLDTGSGRRF-DWRGDEMFPMCSTFKFLLAAAILKRVD -EGRESLTRRIPVSPGDLIPYAPFAETRVNGTPTVAELCEATMTLSDNVAANLLLPAVGDP -AGLTAFVRSLGDERTRLDRNEPTLNSSIPGDPRDTTTPNAMVHSMNRLMVGDALRPSSRE -QLIDWMVGNKTGDKRLRAGLPRDWRVGDKTGTGN-GSINDIGIAWPGARPPILIASYITQ -TPEGFKQGDAIHADVARAATGAf ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009BAABA8 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQFGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000B517F44 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNDVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDANYDNALIAEAAKVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. medellin TaxID=79672 RepID=A0A243NKQ9_BACTV ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=A0A369CNM5_BACAM -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. RUPDJ TaxID=1907305 RepID=A0A1N7D655_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC367F ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=B5ULZ6_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella TaxID=570 RepID=A0A4U9BNP2_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0006A88175 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A5B9HV90_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0012F96446 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium svalbardensis TaxID=368607 RepID=A0A290WSX4_9BURK ---AAQTQLAALEQAAGGRLGVAAWRQGSELRV-TYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKNADTNQAIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 112mf TaxID=1761752 RepID=A0A1H4CV12_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF3F694 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD014 TaxID=1053223 RepID=J8GPN4_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. BJB304 TaxID=1572871 RepID=A0A2G3M8D2_9BURK ---AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNNAIPGEVRDTTSPASMAHSLQQLLLGNSLPAPQRQ -QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00065D48DD --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0007ED6069 ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLVQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDASLKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. BK463 TaxID=2587008 RepID=UPI000DE10D41 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHAGGDMTIGELCAAAITLSDNTAGNLLLESFGGP -AVLTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATASAKDVEAVFAEIAKIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000DF1429C -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000DE8A1F8 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0011A6C8E1 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD79981 --dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-TNRETERFPLLSTFKVLAAGMVLARVD -GGDENLERRVTYDQDKLVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLDSLGGP -EALTKWLRSIGDTSSRLDRIETELNEARKDDPRDTTTPDAMLDTLGNLALGTVLSEPSRQ -QLIDWMIANTTGAARLRAGLPEEWKVGDKTGTGSNGSAADIAIIWPEESSPILVAVYVAE -ATAPVSELNDVFAEVAKLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000F8E88EF -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. RUPDJ TaxID=1907305 RepID=UPI001115678F -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A437SHI4_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMRDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0011DF58C2 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BA751ED -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0010ABE063 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A376I5A8_ECOLX --pTTLNKVKEAESQLTARVGYAELDLISGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILRTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE -SQATLEERNRQIAGIGATLIQHw ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. 11515TR TaxID=2028343 RepID=A0A248W450_9RHIZ ---DVDKQLADLEKRTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVSYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGDNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATASAKDVEAVFAEISKIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001444187F -----NNSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---TEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVNPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B9D365 ------EQIKISESQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1E8B8G5_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLKEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTAGNALPTDKRK -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5J3Q0_9ACTN -----EHEFRQLEEKFDARLGVYAIDTGSGRTV-GYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPVTERHVATGMTLRAIADAAVRYSDNTAGNLMLRQLGGP -QKFEKELREVGDKVTDPARYETALNEARPGDRRDTSTARALAGTLRAYAVGDALEPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDASYDNALIAEATKAVLASw ->[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter sp. wls718 TaxID=2576418 RepID=UPI0010C96F0E --pTTLNKVKEAESQLTARVGYAELDLISGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILRTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYVTE -SQATLEERNRQIAGIGATLIQHw ->[subseq from] Beta-lactamase n=1 Tax=Methylorubrum salsuginis TaxID=414703 RepID=A0A1I4MGC4_9RHIZ -----EDTLAQIEGRVGGRLGVALLDTASGELT-GRRIDERFPLCSTFKVLAAAAVLARVD -GGQESLERRIVFGREALVPYSPVTEPRIDGSMSLAELCEVAVTRSDNTAGNLLLQALGGP -PGLTAHLRSLGDRVTRLDRTEPTLNEAAPDDPRDTTSPAAMVRVLAGLTLGSALSQPSRD -RLNGWLRDNRTGGARLRAGLPPGWRIGEKTGTGERGTTNDVGVLWPPDGAAQVVAVYLTG -SDRPLAEREAALAAVAKAVVE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI000F05B74B ---ETLVKVKDAEDQLGARVGYIGLDLNSGKILeSFLPEERFPMMSTFKVLLCGAVLSRID -AGQEQHGRRIHYSQNDLVEYSPVTEKHLTGGLTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00124AAC2B -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00123716A4 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8IM46_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0010A3977D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A150BSY9_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Legionella taurinensis TaxID=70611 RepID=A0A4T0YGN7_9GAMM ---SLQQKLAALEASAGGRLGIAAINQANGMTI-QYHARQAFPLCSTSKAMSVAALLSQNM -RNKTLLQEKIHYSKQDLVVHSPETEKHLADGMTLAELCEATITQSDNAALNLILKKIGGP -GAVTAFARSIGDKQFRLDRFEPDLNTGIPGDPRDTTTPKAMALSLQKLTTD-TLAAPERQ -LLITWLRNNTTGGARIRAGLPEGWVVGDKTGTGDYGTSNDIGVIWPPHCQPVTLAVYFTQ -PKVDATPNNDVIAAATRIVISAf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2PY73_9BACL ----MDLKFAALEKKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDALSAEKQT -ILIEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPSNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVD-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax valerianellae TaxID=187868 RepID=A0A1G6IGI5_9BURK ------QQLESSLEGRGARLGVAMLDTGSGLSL-GWRQDERFPMASTFKLLLAAWMLERVD -RGQEALDRRVHFEPSALVAYSPVTEKHVGAVITVGELCDATVTLSDNTAANLLLARHGGP -QGYTAFVRGLGDAVTRLDRTEPTLNEATPGDPRDTTTPLAMLQSLRKVALGDALQPASRA -QLVEWIVGTKTGDKRLRAGVP-GWRVGDKTGTGNQGSSNDIGVLWPPGGAPIVVTCYMTQ -TTTAPEKRDATIAEVARQVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. ERR1071 TaxID=2572677 RepID=UPI00119C4300 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGTYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVSKIIVD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7F9J3_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium etli bv. mimosae str. Mim1 TaxID=1328306 RepID=S5RUX8_RHIET ---NVEHRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEENLERRVTYGRDKLVDHSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTEWLRAIGDGTTRLDRTEPTLNEGRKDDPRDTTSPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATASVKDLNSIFAEVGKMITE-- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase KPC-55 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001435C375 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVNTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1W6AGX8_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TGKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-28 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L3HS68_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGV-YANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Class A beta-lactamase n=5 Tax=Streptomyces TaxID=1883 RepID=A0A5P2BMS0_STRVZ ---DAAHRLRALEESYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDVLIRYGRDDLVTYSPRTEMHLETGMTVRELCDATITYSDNSAANLLMRRIGGP -AGVTEFARSLGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTANLRELVLGKALHPLDRG -QLIRWLVENTTGDKRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKQAPLVVSVYTTR -LDPDTPGEDRIAEDITRIAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001363C342 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPEGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI000701581A ----MDLKFDALEKKFNVRLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPVTEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLSSDKQT -ILIKWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00069E0E9A ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAVMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1DC51_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLKEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTAGNALPTDKRK -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0DBX4_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ -AKPGLLDKRIRYSKTALPNWSPITTKNQANGMTVAELSAATVQYSDNGAANLLLKEINGP -AALTAFMRTIGDASFRLDRLEPELNSAVPGDPRDTSTPKAVAESMQKLALGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDYAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] Beta-lactamase n=1 Tax=Massilia plicata TaxID=321984 RepID=A0A4P7B939_9BURK -------TFYSIERNLGGRLGVATIDTATGEND-GHRRDERFPMCSTFKTIVAAAVLARSV -TERGFLRKRLRYTQADIRPHSPVSEKHVADGMTTADLCAATIQYSDNAAANILMQELGGP -AAITAYARTLGDTTFRLDRWETELNTAIPGDERDTTTPLAMARTLKKLLLDDGLPPAQRQ -QLKDWMVGNTTGDTRIRAGAPKGAMVADKTGTSGYGVANDIGVVWVPDRAPVVVVVFTHS -MDKAAEARSEIVAAATRVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=P95675_KLEPN ------EQIKLSESQLSGRVGMIEMDLASRTLT-AWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLRTVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRNVLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 769 TaxID=1262452 RepID=A0A0A8ECN3_9ACTN ------GEFKKLERKFDARLGVYAIDTGTGREV-AYNDAERFAHASTFKALAAGAVLRKYA ---PSGMDKVIKYSKDDLVDYSPVTEKHVETGMTLRELCDAAVRYSDNTAGNLLFDALGGP -KGLNATLKEIGDDATRMERREPELNRWAPGEQRDTSTPRALAKDLRAFVLGNVLGKGERA -QLAKWLQTNTTGAELIRAGMPKDWKVGDKTGAGSYGTRNDIAVVWRPDAAPIVVAIMSNR -STEDAHYDNKLIAEAASVVAH-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=A0A1Q5M7D5_9ACTN -------SLTDLEREYGARLGVYALATGTGATV-VHRADERFALCSTFKTLAAAAVLDRHP ---VTRLDRRVTYTRADLVAYSPVTEKHVGTGMSLRDLCDAAVRYSDNTAANLLLRELGGP -RALTAHLRGLGDRVSRLDHDEPELNSNPPGDPRDTTSPRAVAADYRALVLDDALPAAKRE -LLTDWLVRNTTGDLRVRAGVPRDWKVGDKTGTGDWGRANDVAVLWPPRGAPLVIAVLTER -PDRGADPSDALVAEATRRVL--- ->[subseq from] Beta-lactamase n=1 Tax=Jishengella endophytica TaxID=515350 RepID=A0A2W2CJX9_9ACTN -------DFAPLEGEFDARLGVYALDTGTGRTV-AHRPDERFAYASTFKALAAAAVLADTS ---TEELDQIVKYSRDDLVTYSPITEQHVETGMSLRAIADAAVRYSDNTAGNLLLDRLGGP -AGFQQVLRDIGDEVTEPARWETELNEATPGDTRDTSTPRALATSLKTYAVDDALTAEDRA -VLVDWLKGNTTGDKTIRAGTPDGWQVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -SDKDAERDDALLARATELTL--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243IMP3_BACHU ---ATHREFAQLEKQFDARLGVYAIDTGTNRTV-SYKHNERFAFASTYKALAAGAVLQQNS ---IDELDKVITYTKDDLVAYSPITEKHVDTGMTLGEIADAAVRYSDNTAGNLLFKELDGP -KGFEKVLRQIGDKITHADRFETDLNEATPGDIRDTSTPKALATDLKAFTVGNALPADKRK -ILTDWMSGNATGDKLIRAGVPQDWVVADKSGAASYGTRNDIAIVWPPNRAPIIIAILSSR -DKTDATYNNELIAQAATVTVN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519Z4S6_9BURK ----AEDLLAQLETASGGRLGVAAFDVANNARI-LHRAEERFPLCSTFKVIAVSAILSRST -KDDALLKQRVAIESSEVVANSPITGKHVGAGMSVADLCAAALQYSDNTAANLLVKLLGGP -SAVTAFARLAGDDTFRLDRWETELNSAIPGDPRDTSTPANMARSLQGLALDNVLADPQRD -QLQAWLKGNTTGAARIRAGVPSDWVVGDKTGAGAHGTTNDIAVLWPTQGSPIVLAIYFTQ -PDKNAPMRNDVIADASRIVVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00111FD723 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A443G660_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9XHN4_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIAEATKIVLD-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Chryseobacterium gallinarum TaxID=1324352 RepID=UPI00143CE137 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQ------------ ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=UPI000E04CF54 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -LLLQWMVDDRMAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9AEN8_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS094611 TaxID=2033516 RepID=A0A2A7DZP0_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9XE94_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-TYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIADAAEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UIG8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGVVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTTFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0011A3E474 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobacter sp. Root29 TaxID=1736511 RepID=A0A0Q6M020_9BURK -------RWAAIEAESGGRLGVAVLDTANGQVD-GHRLDERFPMCSTFKWLAASLALQRVD -AGLERLDRRVAVRREMLVSNSPVSEKHVGGDMSIAELCEAAVLVSDNAAANLLLASFGGP -AAITRHARSLGDMKTRLDRTEPALNEARPGDPRDTTTPHAMAIALRSALLGTALSDASRA -RLVQWMEAVRTGVDRLRAGVPPGWRVADKTGTGARGSTNDVAVIWPPQRAPLVVTAYLTD -SKADAARRNAALAAVAREAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. (strain BR816) TaxID=1057002 RepID=UPI0003805C7E ---DVTSRLAALEKRTGGRLGVAVLDTETNISF-GHRQTERFAMCSTFKALAAACALARVD -RGEEKLERRITFGKDVLLPHSPVTEKYAGGNMTVAELCDAAITISDNAAANLLLESFGGP -AGLTAWLRSIGDKTTRLDRTEPDLNEAKFGDPRDTTTPAAMLETLGKLAFGSVLSEGSRQ -QLVEWMVANTTGDARLRAGLPGDWRIGDKTGTSSTGAVSDIAFAVPKGRGPILISVYTGE -ATVKPAELNPVFAEVGKIVA--- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI00084CB3D2 ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTTFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Xylophilus sp. Leaf220 TaxID=1735686 RepID=A0A0Q4H1E5_9BURK ---EARAAFARIETAADGRLGVCAFRTDGGPVV-QHRAQERFPACSTFKTLAAAAVLARSD -AVPGLMDRVVRYGPADLVNYSPVTSKQVGEGMTYAALCAAALQYSDNTAGNLLLREIGGP -EGLTRYARGLGDTEFRLDRWETALNDAVPGDPRDTCTPGGMARNLQRLLLGDALAPAHRA -RLTEWMRGNTTGGARIRAGVPAGWPVADKTGSGDYGTVNDIGVAWPPAGSPLVIAVYFTR -AVPDAPLRHDVVADAARAVVR-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009BF1371 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R72 TaxID=1764278 RepID=A0A246U819_9RHIZ --dEINRRMDALEKAIGGRIGVSAIDTDTNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDDTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLTQGSALSEPSRD -KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVIWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001082A507 ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGGRGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000159752D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus tropicus TaxID=2026188 RepID=UPI000BF79145 --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMSDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2DB95C ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAVTLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. 7MK8-2 TaxID=2419777 RepID=A0A494X6L9_9BURK ---QIEARLAQIEREVDGRLGVAIYDSASGLTA-GHRMHELFPMCSTFKFLAAAAVLARVD -RREEDLARRIMYARSDVVIASPATEKHTDTGMTMGELCEAAITLSDDTAGNLLLASFGGP -AQLTAFVRQLGDTVTRLDRNEPTVNEAIPGDPRDTTTPIAMLADMRNVLLGDVLTAQSRA -QMIAWLVGCQTGGAKLRAKLPKDWRVGDKTGGGEHGTHNDIAIMWPPERAPIFVAAYLTQ -TDAPFARCDAALADVGEAVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42) TaxID=326423 RepID=A7Z3J5_BACVZ -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Catellatospora sp. H14505 TaxID=1969805 RepID=UPI001183A4E9 ----AATAFADLETRFDARLGVYAIDTGTGRTV-EHRADERFAYASTFKALAAAAVLDTTT ---AEQLDRVVHYTDADLVTYSPVTEKHVQTGMSLRDLADAAVRYSDNTAGNLLLDHLGGP -DGFEKALRGLGDQTTDVARREPELNQATPGDTRDTSTPRALVDDLRAYTLGDGLADDDRT -VLNDWLRGNTTGAKLIRAGVPAGWQVGDKTGAAAYGTRNDIAVIWPTDGAPIVLAILSSH -DEQDAKYDDALIAQAAAAAI--- ->[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D112268 ----MDIKFAALENKFDARLGVYAIDTETDLAV-AYRQDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLPSDKQT -ILIEWLQGNTTGDKLIRAGLPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Aureimonas ureilytica TaxID=401562 RepID=A0A175R6F5_9RHIZ ---DLDALWAEIENRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD -AGQENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALTQSDNTAGNVLIDLLGGP -EGVTRTARGFGDESFRLDRRETALNEAKPGDPRDTTSPAAMTKTLHALLFGEALKPDSRR -QLADWMVANRTGDAKLRAGLPKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILISLYLTE -TKASFDERNAAFAEVGRAL---- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 17Sr1-1 TaxID=2202826 RepID=A0A2U8X864_9RHIZ ---DTVARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPMCSTFKAIAAAAVLARAD -AGKDDLNRRIAYGRDALLSYAPVTTKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP -GGITAFARAHGDTVTRLDRTEPTLNTAIAGDVRDTTSPAAMVGLLENVLLGRALSAESRA -RLIGWMHDSPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEIGRLIAR-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007ABDA07 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEMAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A5Q3KQ94_9BACI ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces formicae TaxID=1616117 RepID=A0A291QG68_9ACTN ---DVRRRLRELEKGYPGRIGVHALHTGTGATV-GYRADERFAIASTFKVLAGAAILRRAR -EEPGLLDVLIRYGRDDLVTHSPRTEMHLETGMTVRELCDATITYSDNAAANLLMRRIGGP -SGITEFARSIGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTENLRKLVIGDALHPLDRD -QLIRWLLENTTGDQRIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPKGAPLVVSVYTTR -LDPDTPGEDRIAEDITRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. corylina TaxID=487821 RepID=A0A2S7CG57_9XANT ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIHNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI0011A8A998 -----SRSIVALEARSGGRLGVAVLDTANGKTF-TYRGDERFAMCSTFKALVAGLVLKRVD -QGQERLDRRIPYGPGVLLAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLHTFGGP -PALTAFLRGLGDTVTRLDGYEPGLNVVRPGEIHDTTSPSAMLATLRALTLGPVLSAASRQ -QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWSVGTTNDIAVTWPPGRPPLLITAYLSR -STLDDDGRNAVIAEVARLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus wulumuqiensis TaxID=1567107 RepID=UPI0006197A67 ----VVTSLKHLEQQHKGRVGVYAVDTGTGRVV-AYRHNERFAFASTYKALAAAAVLQQSS ---ISDLDRVITYSADDLVEYSPITEKHVETGMTLREICLAAIQYSDNTAGNILFQELNGP -AGFQQALRQIGDTVTRSERIEPELNEIVPGDSRDTSTPRALARDLRLITTGKVLTQDKRQ -LLTEWMKGNTTGDQLIRAAVPKGWVVGDKTGSAAYGTRNDIAIIWPPDRAPIIMAILTDH -DDKDAKTDNELVAKAARITLK-- ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=I1YAX3_ECOLX --------------------GYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Desulforhopalus sp. IMCC35007 TaxID=2569543 RepID=A0A4V5NS63_9DELT --pGLTETIQQIEKNLDARIGVAVYEEGTGRNW-QYHADDRFPMSSTFKTLACSTLLSRVD -AGQEKLDRSVVFEEKDLVTYSPVTKTRVGASMSLSELCEATMSMSDNSAANFILRNIGGP -EAVTTFVRSVGDTITRLDRWEPDLNEATPGDVRDTTTPNAMVQTLKSLVFGDTLNLRSRE -QLINWLKGNKVGDALFRAGVPSTWVVADKTGAGGHGSRSIAAIMWPPKSQPIIATVYITE -TEATFDARNAAIAEIGEVIAR-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. C5 TaxID=2035448 RepID=A0A2A6JGF4_9RHIZ ---NVERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGGERLRAGLPQEWKVGDKTGTGPNGSLGDIAVIWPPDRGPIAAAVYIAE -ATVPVKDLNPIFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. J33 TaxID=935836 RepID=UPI0004B08B11 ----IEEAFTQLESKFDARLGVYAIDTETEKSI-AYRADERFAFASTYKALAAGAMLKQKS ---LNDLDEIITYTKDDLVTYSPITEKHVDTGMSLRDIADAAIRYSDNTAGNLLLKELGGP -AGFETALREIGDKVTESDRFEPDLNFTVPGDSRDTSTPRALATSLQAFAASDLLPSEKRA -LMTDLLVGNTTGDTLIRAGVPEGWVVGDKSGAGTYGTRNDIAIVWPPNSDPIIIAILSDR -STEDAAYDDALIAEAAKIVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0P0IBD9_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMSATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. SYJ TaxID=2529386 RepID=UPI000B43EF9D --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVRNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0007F910AE ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTALPSYPRDATAARGMAQTLRNPTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AC02A6 -----NQKFVQLEKKFDARLGVYAIDTGSNQTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=A0A1W6HH11_BACVA -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF9E835 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=8 Tax=Bacillus TaxID=1386 RepID=A0A5B2T408_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7E4FF ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA6778 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILTNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0005CE21C6 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Roseomonas TaxID=2617492 RepID=A0A1Q2YQ29_9PROT ----LPAVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD -AGQARLDQRIRYGREKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP -AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA -HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGAGERGTNNDAGLLWPPGEAPILVAAYSTG -GTAPSTERDAALAEVAAAIVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. LUNF1 TaxID=2709781 RepID=A0A6C1CMU7_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora humi TaxID=745366 RepID=A0A1C5JNY2_9ACTN -----DREFRRLEQEFDARLGVYAVDTGTGRTM-GYRADERFAYASTFKALAAAEILDETT ---DAELDKVVRYSADDLVTYSPITEQHVDEGMTLRAIADAAVRYSDNTAGNLMLRRLGGP -QKFEKELREVGDKVTDPARWETDLNEARPGDRRDTSTPRALAGSLRAYAVGDALEPADRD -VLNGWLRGNTTGAELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDAEYDNALIARATEVALAGw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00128FB05C -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD592E8 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGRDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella quasivariicola TaxID=2026240 RepID=UPI001181F252 ------EQIKISESQLSGRVGYVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVERLDRRIHYRQQDLVAYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLDTLGGP -AGLTAFLRTIGDNVTRLDRRETQLNEALPGDVRDTTTPASMAATLRKLLTAKHLSARSQQ -QLVQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD -TPATIAERNQQIAAIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D663E90 -----NQKFVQLEKKFDARIGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] Putative carpapenem-hydrolyzing beta-lactamase KPC-14 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=K4NUK1_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGV-YANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE57A77 --nDIEKQLAALEKRTGGRLGVFVLDTKNNVSF-AHRPDERFAMCSTFKALAAAFVLARAD -MGEEKLDRRIPVSKKDLLSYSPVVEKHVGDGMTVRELCDAAVTYSDNAAANLLLASFGGP -KGLTTWLRSIGDLTTRLDRTEPELNEAKVGDPRDTTTPMAMTETLGRLLLQDVLSPSSRE -QFAAWLVANTTGDRRLRAGLPQDWTIGEKTGTSGRGEAGDIGFMRPRDGHTILASVYIAE -GKKPTKELEPVFADVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BSE7F TaxID=2175092 RepID=UPI000D6104C8 -------SLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRA -LLTDWLVRNKTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Raoultella sp. BIGb0399 TaxID=2485119 RepID=A0A3N2EV52_9ENTR -heATISRVKTAESQLQGRVGYAELDLTTGRLLaGYRADQRFPMMSTFKVLLCGAVLARVD -SGEEKLDRRIHYRQQDLVEYSPQTEKHLDDGLTVGELCAATITLSDNTAANLLLTAIGGP -QGLTAFLRRSGDRTSRLDRREPELNAAVPGDVRDTTTPQAMATTLRRLLTGGVLSASSQQ -QLQRWMIDDQVAGPLLRASLPSGWFIADKTGAGQRGSRGIIAALGPDGKPSRIVVIYLTD -TDATMAVRNQQIAEIGATLVENw ->[subseq from] Beta-lactamase n=3 Tax=Hydrogenophaga TaxID=47420 RepID=A0A1L1P864_HYDIT ---ELDAAVRELESQSRGRLGVHFIDTGDGREW-GYRSDERFLMLSTFKTLASALVLERAD -QGKAPLSKRVRYHQRDLVQWSPVTEKHVGGQLSLAQLCEATITTSDNTAANLILREVGGP -AALTAFLRRIGDPVTRLDRTEPELNEPSPGEDLDTTTPRAMARSLRTLLLGEALSPASRE -QLAAWLKANTTGDKRLRAGVPPSWGIGEKTGTAGP-SANDAGIVWPPGAAPILVSAYLAD -SPASAAVRERTLAGVGRLLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZR62_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSXI-LYRADERFAMCSTSKEMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAE----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI00061CCFD1 ---SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA -SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV -ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE -QLAVWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKTAPIVLVIYFTQ -REKDAKPRRDVLAAATKILLSH- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. JE062 TaxID=439495 RepID=UPI00055DF5C9 ---ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ESRADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA -QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLAAVYMTG -SDANFKKRNAVIAEIGKAIIE-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter sp. yr284 TaxID=1761791 RepID=A0A1H3PNL6_9GAMM ---ALRAKLAELEKRSGGRLGVSALDSGDGRRF-DVRGGERFAMCSTFKFLLSAAVLHKVD -RGDLDLQQRIAVPKSALVPHAPFTGPLAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP -DGLTRFLRGIGDPTTRLDRNEPELNTAIPGDPRDTTSPNAMLASMRALLLGDALSAASRT -QLADWLIANKTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPSGRKPVFIVTYLTQ -ATGEDEQRSAILADAARALFEHw ->[subseq from] Beta-lactamase n=2 Tax=Acetobacteraceae bacterium AT-5844 TaxID=1054213 RepID=H0A5X7_9PROT ------ATFARIEAERGGRLGVAVLDTGSGRKA-GHRVDERFPMGSTFKTLASAAILARVD -AGKESLQRRIRFSRADLVTYSPVTEKNVGGDMTLAALCEATITTSDNTAGNLLLNALGGP -AALTAWLRSLGDNVTRLDRMETALNEARPDDPRDTTSPSAMAADIHALTLGEALSQGSRQ -QLIRWLRDNKTGDARLRARLPAGWTAAEKTGTSGNNTSNDVGLLFPPGGAPIVVAAYLTQ -GAAKGAIRDAALADVGAAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. S-93 TaxID=2653122 RepID=UPI001260437A ---DVDKQLADLEQKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEISKIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. BK100 TaxID=2512181 RepID=A0A4R1ZW83_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodospirillaceae bacterium TaxID=1898112 RepID=A0A5C7NPY1_9PROT ---RLQAELAKIEASSGGRLGVAIRDTAIGMTV-GHREKERFPICSTFKFLAAAAVLKRVD -MHQENLDRRIVFSRKDLVHYSPVTEQRTGGEMTVAEICDAAVAMSDNSAGNLLLRSLGGP -SGITLFTRSLGDNMTRLDRWETDLGEATPGDPRDTTTPASMLNNLQKLLVKTTLSEPSQA -QLLEWLVACKTGDNRLRAKLPKDWRVGDKTGSGNHGSANDVAILMPPDRAPILVTVYLTQ -TDASPSDRDAAIAEVGHLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=A0A0U1HQ02_YERRO ---SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA -SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV -ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE -QLAVWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ -REKDAKPRRDVLAAATKILLSH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00102EBB88 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNKRFAYASTYKALSAGAVLQQNS ---IDKLNEVITYTKNDLVTYSPVTEKHVDTGMTLGEICEAAIRYSDNTAGNLLFKKLNGP -KGFEEALRQIGDKVTVANRFETDLNEAIPGDIRDTSTAKTLATDIKAFTVGNALPADKRK -ILTDWMRGNATGDKLIRAGVPKDWEVGDKSGAGSYGTRNDIAIIWPPNRAPIIIAILSSR -DKKDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHY5_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5BB78 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGNNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI001047BFDD -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Gluconobacter wancherniae NBRC 103581 TaxID=656744 RepID=A0A511B0D5_9PROT ---DVHRKLAWIERKSGGRLGVCAYLSGTTRPAvTYRGGERFPMCSTCKALLSAAVLARVD -RGRESLSRKILIRPQDLMHYSPITQPHIGTALTLGDMCSAAVSYSDNTAANALLRVLGGP -AMVTAFARSIGDTVTRLDRWEPALNEALPGDPRDTTTPEAMSRNLTQLLSGDALSSASRR -TLLEWMVANQTGDARIRAGVPKSWRVGDKTGTGSRGTINDIAFIMPPEKTPFALSIYLTG -SPLSANAGNAIIAEIARTIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=D5LIR5_ENTCL ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELRAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGTGAAPIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae 30660/NJST258_1 TaxID=1420012 RepID=A0A0E1CLX4_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGT-ELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4L6J3_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00119EEEE5 -----NQSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -NEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. LP_7_YM TaxID=2485137 RepID=A0A4R7WV13_9PSED ----IEQQLAELELRHGGRLGVAILDTGSQRLI-THRGDERFALCSTFKALAVAHVLARVD -RKEEDLSRLIVYGKDQLVTYSPVTEKHAGNPLSVGSICEAAITLSDNTAANLLLDSFAGP -EGLTDWLRSMGDQTTRLDRREPELNENRPGDLRDTTTPVAMLQSLRTLVLGNALSAASRD -QLVAWLGSNKTGDQKLRAGLPKGWRVGDKTGLGANNASNDVAVIWPSERAPLIVTLYSTG -SHANAEQINALMADVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000C75AAF4 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0011ACA0E0 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -VLTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF918F5 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. LP_7_YM TaxID=2485137 RepID=UPI0010611361 ----IEQQLAELELRHGGRLGVAILDTGSQRLI-THRGDERFALCSTFKALAVAHVLARVD -RKEEDLSRLIVYGKDQLVTYSPVTEKHAGNPLSVGSICEAAITLSDNTAANLLLDSFAGP -EGLTDWLRSMGDQTTRLDRREPELNENRPGDLRDTTTPVAMLQSLRTLVLGNALSAASRD -QLVAWLGSNKTGDQKLRAGLPKGWRVGDKTGLGANNASNDVAVIWPSERAPLIVTLYSTG -SHANAEQINALMADVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. R635 TaxID=1764275 RepID=A0A246TBV4_9RHIZ ---NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRGGEAFPMCSTFKALAAGFVLARVD -KGEESLDRRVSYGKEKLVDYSPVSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSILTEASCN -RLIAWLVASTTGKERLRAGLPQDWKAGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -AIVPAKELNPIFAEVGRMIAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. YR290 TaxID=1882799 RepID=A0A2C8Y6M9_9BURK ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -RGKEQLGRTIVYSKEAVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRVGDKTGTGERGTSNDIAVIWPEGRAPILVAAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009B510BA --qATHKEFSQLEKKFEARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYENALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAKNLKDFTVGNALPDYKRK -VLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIVAILSSK -DEKEATYDNQLIAEATEVVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium tibeticum TaxID=501024 RepID=A0A1H8FXD3_9RHIZ --dEINRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETERFPLCSTFKVLAAGLVLARVD -KGQDTLERRVVYDQAKLVTYSPETEKHVGGEMSLSELCEAAITLSDNTAGNLLLESFGGP -PELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLALGSALSEPSRD -KLTEWMVANTTGGARLRAGLPGTWRIGDKTGTGNNGSAADIALVWPPGHGAILVAAYVTQ -ARAPLSEINPVFAEVGRIVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacilli bacterium VT-13-104 TaxID=1637974 RepID=A0A0K0GDZ5_9FIRM ---KIDNQFSQLEEEFDAELGVYAVDTETNQAI-EYQSEERFAFASTYKALAAAIVLQQNS ---MEELNQVITYTKEDLVPYSPVTEKHVDSGMTLLNLAEAAVRTSDNTAGNLLFNAIGGP -KEFEQTLREIGDNDTQAERYEPDLNQFSPEDPRDTSTPKALATSLQAFALGDLLPNEKRE -QFTDWLQGNATGDTLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNREPIVIAIMSRH -DTEDATYDDALIAQAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. LS-2 TaxID=2315859 RepID=A0A3A6RM48_9PSED ---SIEAQLAALELRHGGRLGVAILDTGNQRLV-SHRGEERFALCSTFKALAAAYVLARVD -LKDEDLSRLIVYGQDQLVTYSPVTEQHAGEGLSVGSICEAAVTLSDNTAANLLLDSFGGP -PGLTAWLRSIGDQTTRLDRHEPELNENRPGDLQDTTTPIAMLQSLRTLLLGEVLSGASRD -QLSAWLASNKTGDQKLRAGLPKGWRVGDKTGSGSNNASNDVAIVWPTDRPPLIVTVYYSE -SKATSEQINSLMAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BEE1A58 -----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFIYASTSKALAVGALLQQKT ---IDDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP -NGLEKSLRDVGDNVTMPEQFEPELNDVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGDPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. PML113 TaxID=1899350 RepID=UPI000879024D ---ALDAAARALEAKSRGRLGVHILDTADGREW-GHRSDERFLMLSTFKTLAAALVLRRTD -QGKAPLSKRVRYRQRDLVQWSPVTEKHVGGRLSLAQLCEATITTSDNTAANLILREVGGP -AALTAFLRGIGDPVTRLDRMEPELNEPSPGEDLDTTTPRAMARTLRTLLLGDALSPASRE -QLAAWLKANTTGDRRLRAGVPPIWGIGEKTGTAGE-SANDAGIVWPPGRAPLLVSAYLAD -SPAGAAAREQALAGVGRLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00099C0B9F -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSNKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A2B8JYJ1_BACME -----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFIYASTSKALAVGALLQQKT ---IDDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP -NGLEKSLRDVGDNVTMPEQFEPELNDVKPGETHDTSTPRALATSLQSFTLGDVLPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGSGSYGTRNDIAIIWPPKGDPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0006680D59 ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY76_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI001440FE84 ---NVERRLAELEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDESLDRRVSYGKDKLVDYSPISEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAILDTLGNVTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio sp. JE062 TaxID=439495 RepID=B6QWS2_9RHOB ---ELLDTVNRLENEVGGRIGVVLQHTGSDWAI-ESRADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA -QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLAAVYMTG -SDANFKKRNAVIAEIGKAIIE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A3R7E0T2_9BURK ---AIRQRLAQIEVESGGRLGVSILDTTSGLHA-GLRTDERFPMCSTFKLLAAGLVLTRVD -RGQEDLERCIVFSKSDLMPYSPATSEHTRERMSVADLCKAALTLSDNTAANLLLASFGGP -AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGNLRELLLGERLSSLSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPILVTVYLTE -TSGDAARCNAAIASVGALVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium mesoamericanum STM3625 TaxID=1211777 RepID=K0PE23_9RHIZ ---DINRRMDALEKAIGGHIGVSAIDTDTNISF-GYRETERFPICSTFKVLAAGLVLARVD -KGQETLERRVVYEKDKLVTYSPETEKHVGGEMSLSELCQAAITLSDNTAGNLLLESFGGP -AELTKWLRTLGDRSTRLDRWETALNEVKDGDPQDTTTPDAMVDTLGNLTLGSALSEPSRD -KLIEWMVANTTGGARLRAGLPDTWKIGDKTGTANNGSAADIAVVWPPGHGAILVAAYVTQ -AKAPVSEINPVFAEVGKIVAD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00099244DA ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2A7CHS8_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKHDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. VMFN-A1 TaxID=2135607 RepID=A0A2V1ZAP8_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SMS_SU21 TaxID=2069440 RepID=A0A2U2EX30_9ACTN -------SLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GTRLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRA -LLTDWLVRNKTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033E322 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae subsp. similipneumoniae TaxID=1463164 RepID=A0A455LWB5_9ENTR ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D16A7BD ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMVDRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F615_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVAIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B2GRM4_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSERFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWEVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000C228E44 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYDNALIAEAAKAALN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A6A8LHP4_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00100ADA6F -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYDNALIAEAAKAALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B44776F -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000BA60ED6 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000D6AF686 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI001039783B -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00118657E4 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9YFA7_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVVIN-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001033F4B6 ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRLIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00046EC1EC -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0005187735 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001118123A -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00128F8CE7 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=A0A0N0TN39_9ACTN -----DHEFRRLEERFDARLGVYAIDTGTGRTV-QYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITEQHVADGMTLRAIADAAVRYSDNTAGNLLLRQLGGP -QKFEKELREIGDKVTDPERYETALNEAKPGDRRDTSTARALAGSLRAYAVGDALESADRD -ILNGWLRGNTTGDELIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDADYDNALIARATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. CF318 TaxID=1144318 RepID=J2LB99_9BURK ---SATRRLAAIEKTSGGRLGVSILDTGSGAKY-GYRAGERFPMCSTFKLLAAALVLHRVD -AGQEQLDRRIPIAAGDILPHSPTTQQHIGPQLPMAALCEASIIVSDNAAANLMLASFGGP -DGLTTYLRGLGDKMTRLDRTEPELNESAPGDVRDTTTPDAMLATVHKLTLGSALSDASRQ -LLVQWLQANTTGDRRLRALLPPGWRVGDKTGTGAHGSTNDVGLIWPPGRPPLLVAAYLTG -TQQPAAQRDVALAKVGQLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00049836B4 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLDEVITYTKDDLVEYSPITEKHMDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNALPTDKRK -ILTDWMRGNATGDKLIRSGVPKDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DKEDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Verrucomicrobia (miscellaneous) TaxID=417295 RepID=A0A1Q6V7G7_9BACT ---DAADQIAAIEARLGGRIGVAGLDTGNGKRI-DYRAEERFPLCSTFKFLAAAAVLKRVD -EKKDKLDRFVSYDAKDILEYAPVTKAHLGNGMTLGALCAAAIEQSDNTGGNLLLEAIGGP -VGLTNFARDLGDRMTRLDRKEPELNSAIPGDDRDTTTPASMLGDIRQLLVGNTLSASSRQ -QLQEWLQANETGAAMIRAGIPTNWIVGDKTGRGANGATNDVAIVHPPDRAPILLAIYCVG -STASANDRAAAVAEAAKVVAESf ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI000E0BFEEF ---SVRDALAALERTSGGRLGVCAIDTEGGRAI-GYRADERFAVCSTFKVVLAAAILARSL -DVPGLMQRRIRYTKQDLAHYSPVSSKHVRDGMTVAELCQAAIQYSDNTAANQLMKVLGGP -QAVTAYAHATGNTAFRLDRWETELNTAIPGDLRDTSTPAAMAHTLETLTVGQALPAAQRD -QLVTWLRGNTTGAHRIRAGVPGDWAVGDKTGTGDYGTTNDLAILWPPRRAPVMLAVYFTQ -REPKAKARDDVIAAAARIVA--- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0011A212D2 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2) TaxID=395965 RepID=B8EL76_METSB ---ELQGALADLEQKHGGRLGVAILDTATMRLI-ARRGDERFPLCSTFKFLAAAFVLARVD -RKEESLARRIIYASDVLVAHSPITGKYVGGDLTVGEICEAAVTVSDNTAGNLLLDSFGGP -AGLTAYVRSLGDNFTRIDRRETELNEAAPGDPRDTTTPLAMLEILHKTVLGTSLSAPSRQ -QMIAWLVANTTGGQRLRSGAPKGWRVGDKTGSGENNTTNDIAIIWPPQRAPLIVTAYYTE -ARASAVERDAVLSEVGRLAAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA63517 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A411A4U6_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Lentibacillus halodurans TaxID=237679 RepID=A0A1I0Y6W0_9BACI ---SITDDFAKLEDEFDARLGVFALDTGTNETV-TYRPDERFAYASTFKVLAVGALLQQKS ---IADLNQRITYTRDDLVNYNPITKKHVDTGMTLKELCDAALRYSDNTAANLILEQLEGP -SGLKKSLREIGDHVTEPARIEPALNEVKPGETHDTSTPKALADSLQAFTVGDVLPTEKRV -MLIDWMKRNTTGDTLIRAGVPESWEVADKTGAASYGTRNDIAIIWPPEGDPIVLAILSSR -DKKDAEYKDKLIAQATEEVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A4V6F1F1_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=A0A2I7TEY5_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI001249B30D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium laguerreae TaxID=1076926 RepID=A0A1S9H449_9RHIZ ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLGRRVSYGRDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTETSSD -RLIAWLVASTTGKVRLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPIFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000E22C3FB -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BB769C3 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000AA07041 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A6C1WDG0_BACLI --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas formosensis TaxID=861534 RepID=UPI0012F75850 ------DRFQILEKIGGGRLGVAVYDGETQRYN-GWRGHERFPMCSTFKLLAAALVLHRVD -RGVESLDRRVTYGQDSIVAYSPVTEQRIASGMTVGELCEAAITRSDNTAGNLLLASFGGP -PALTAFARRLGGGRTRLDRTETELNSALPGDRRDTTTPRDMVDMMRRLFFGRALSAPSRT -ILLGWLGANQTGARRLRAGLPSGWTIGDKTGTGDNGTANDVAILWPPGRRPMLIAVYLTQ -APGASASLDAIIAEVARTAT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T9B8_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCRAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000CD585AD -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Stella sp. ATCC 35155 TaxID=2558175 RepID=UPI00113CCFCD ---ATAARLADLEARHGGRLGVSALDTGTGRRI-EHRADERFPMCSTFKLLAAACVLSRVD -RGEERLDRRVVFQASDLVAYSPATEKRVGGDMTMAEICAAAMTLSDNTAGNLLLASFGGP -PALTAYARSLGDRVTRLDRIETALNEGAPGDPRDTTTPGAMLDDLCALVLGTALSEPSRA -QLTTWLLDNRTGDRRLRAGFPGGWRVGDKTGTGGNGAAADVAVVWRPELPPLAVAVYWAE -ADVPFEGRNAIFEAVARIL---- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A1I4HKX1_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001370DC69 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI0010334513 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPVVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE4FFAD ---DIEKQLAALEKRTGGRLGVYVLDTKTKVTF-AHRPDERFAMCSTFKALAAAFVLARVD -KGEEKLDRRIPISKKHLLSYSPVVEKHVGSGMTVGELCAATVTYSDNAAGNLLLASFGGP -KGLTDWLRSVGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLLEDVLSPASRD -QFSAWLVANTTGDRRLRAGLPKGWIIGEKTGTSGRGEAGDIGFMRPAEGHTILASVYIAE -GKKKTKELEPVFAEVGKLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS075960 TaxID=2034282 RepID=A0A2B4LHF5_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTI-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNLITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Dankookia rubra TaxID=1442381 RepID=A0A4R5QKH0_9PROT ----AAEALAALEARHGGRLGVAVLDTGSGQRL-AHRAGERFPLTSTFKFLAAGRVLARVD -RGEEGLDRMVAYTKADLVTYSPVTGQQA--AMSIGALCDAAVTFSDNTAGNLLLDSFGGP -AGLTAWLRGLGDAVTRLDRRETALNEARPGDPRDTTTPTAMLGLMQVLLLGEALAAASRA -QLAAWLVGCRTGDRRLRAGVPAGWRVGDKTGSGEIGTANDIGILWPPGRSPILVAAYSTG -SAAPEEARSAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BEBF425 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLDEVITYTKDDLVEYSPITEKHMDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFTVGNVLPTDKRK -ILTDWMRGNATGDKLIRSGVPKDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DKEDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A120EBT6_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BA2C435 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR -FTEDANYDNALIAEAAKAALN-- ->[subseq from] Beta-lactamase n=2 Tax=Roseomonas gilardii TaxID=257708 RepID=A0A1L7AIX8_9PROT ----LPAAFAGIERRVGGRLGVAVLDTTTGQRA-GYRETERFPLTSTFKLLAAAAVLARAD -AGQARLEQRIRYGREKLVTYSPETEKHAGEEMTLAAICEAAITLSDNTAGNLMLEQLGGP -AGLTAWLRSIGDEVTRLDRWETALNEAKPGDPRDTTSPAAMLASLQRVTLGEALSDKAQA -HLSGWLRASRTGDKRLRAGLPAGWQAGEKTGAGERGTNNDTGLLWPPGGAPILVAAYSTG -STAPGTERDAALAEVATAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000D6ADB69 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR -FTEDANYDNALIAEAAKAALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AM1(2019) TaxID=2665175 RepID=UPI0013634C24 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B8C692D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHMDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B8BDFF5 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000C1C6927 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYNNALIAETAKVALN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=A0A244DTI8_9BURK ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRTIAYSKEVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDSAIAQVGALVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. OV484 TaxID=1500308 RepID=UPI0006455538 ---ALNSRINDLEQRSGGRLGVAVLDTQTGRRF-AWRGDDRFRMCSTFKMPLAAAILRRVD -QGREQLDRRITYGRDVLMGNSPVVEKHLGEGMTVAALCEATITWSDNAAANLLLDALGGP -ASLTRFLRAIGDQTTRCDRREPELNTGAPDDPRDTTTPSAILGTWKTLLLDDALSPASRK -QLTAWVVANRTGDKRLRAGLPSGWRVGDKTGNNGKDTTNDIAIAWPRGRKPILIAAFHDR -GSADDDARSAVHADLARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. YR710 TaxID=1882773 RepID=A0A1G6IF48_9SPHN ---DISTQLADLERQSGGRLGVAMLDCGNGRLV-GWRLDDRFPMCSTFKVMLAALILHRVA -IGEERLDRRIVVGTADLLSYAPVTSKYVGDPMTIEALCEAAVTMSDNTAANVLLTTSGGP -TALTRFARGIGDRETRLDRIEPALNEARAGDPRDTTTPAAMARSLRKLALGSALPADGRA -LLTRWLIGCRTGAARLRAGLPAGWAVGDKTGTGGRGSTNDIAVIWPTGRDPVIVAAYMTG -VTLGADAREAILASVGRLAAAQf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFB569 ---DIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRVKYGKEKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D623_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEEBCEB ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRYAEGDPRDTTTPAAMAVTLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI0003B1E939 ---TLKSQFETLENKSGGRLGVTVVDTSDGSEY-SWRGNEIFPLCSTSKLMAVAAILKKNE -SDHSLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATHFARTIGDKAFRLDRKEPELNTAIPDDVRDTTTPSAMADTLNKLVLGTALKGEQRA -KLSEWMKGNTTGANSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKDQAPIILTTYFTQ -KDKDAVARKDVLASAAKLVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis albispora TaxID=1804986 RepID=A0A344LM52_9PSEU ---AVEQEFTRLQTQHDARLGLYALDTGSGKSV-AFRADERFAYASTFKALAAAAVLDNTT ---PQQLDEVVHYTADDMLENSPISKQHLDTGMTLRDLCDAAIRYSDNTAGNLLLRRLGGP -AGLDAALTAIGDDVTSADRYEPDLNSAIPGDTRDTSTPRAMAGNLRQYVLGDALAEDDRT -LLTDWLRRNTTGATVIRAGVPADWIVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAIMTSR -DEPRAKRADALLADAARVAVS-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00077AE8C1 ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQKNS ---TEKLNEVVTYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRLETELNEAIPGDNRDTSTAKAIATNLKDFTVGNALPDKKRN -ILTDWMRGNATGDKLIRAGVPKDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. S184 TaxID=1641862 RepID=UPI00131A96BE -----AAQLATLERQRGGRLGVAILDTDNGRRI-GHRADERFLMCSTFKLLAVAAVLARVD -RGVERLDRRIVFGKEAVLAYAPVTSQRVGAPMTVAELCQAAITLSDNTAANLLLASLGGP -AAVTAYVRSLGDDVTRLDRIEPELNVGRPGDLRDTTTPSAMLADLHTLLLGEVLSATSRE -QLTTWLCATSTGTEQLRAGMPAGWRVGDKTGSGANRETNDIAIIWPQKRKPLLVTAYYAG -STADTGERHAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EXF4_9BURK ---ALARAVQEVEASVGGRLGVALLDMATGRQD-AHRGDERFPLCSTFKLVLAAHVLRRVD -QGQERLDRRITYGKSDLMEYSPATERHADGDMTVEQLCEAAVTLSDNTAANLLLGTQGGP -LGLTAWLRSLGDSQTRLDRMEPALNDVPPGEVRDTTTPRAMARTVWAVTQGEALSAAARA -RMLAWLVGNRTGDRRLRAGMPEGWRIGEKTGTGPRGTSNDIGLFWPPDRGAVMVSCYLTG -SPAPAEQRDAALARVGALAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000CE00184 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000FFB8A21 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA525C4 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIIWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas mucosa TaxID=207340 RepID=A0A1S8D217_9PROT ------AVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD -AGQARLDQRIRYGRDKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP -AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA -HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGAGERGTNNDAGLLWPPGEAPILVAAYSTG -SMAPSTERDAALAEVAAAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0012D981B6 -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAFASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BA523BC -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B4484C2 -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B9270AD -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000E433FBA -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI000BA75BB9 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAHNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF60919 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKADAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8AI20_9BACI ---TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFGLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSFGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BEB8D08 ---ATHREFAQLEKKFDARLGVYAIDTGTNQTV-TYRPNERFAYASTYKALAAGAVLQQNS ---IDKLDEVITYTKDDLVEYSPITEKHMDTGMTLGEIAEAAIRYSDNTAGNLLFKKLDGP -KGFEKALRQIGDKVTMADRFETDLNEAIPGDIRDTSTAKTLATDLKAFAVGNVLPTDKRK -ILTDWMRGNATGDKLIRSGVPKDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DKEDATYDNELIAQAAKVTIN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root1203 TaxID=1736427 RepID=A0A0Q6S9J1_9RHIZ ---EIDRRIGELEKRIGGRIGVSAIDTQTNVSF-GYRETESFPMCSTFKVLAAGMVLSRVD -KGQENLERRIVYDKDKLVTYSPETEQHVGGEMSVGELCKAAITLSDNTAGNLLLESVGGP -KELTNWLRTLGDGSTRLDRWETDLNEAKKDDRRDTTTPDAMLDTLGNLALGSVLSEPSQN -TLVEWMVANTTGAARLRAGLPDSWKIGDKTGTGNNGTAADIAIAWPPGHGPVLITTYVAE -AQVPVSEINPIFAEVGRIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A076VE11_ECOLX --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLDLLNFFTQ -PPSRAES---------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI000DE9EC76 ------HKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVVQQNS ---MDELDEVITYTRDDLVTYSPITEQYVDTGMTLREISDAAIRYSDNTAGNLLLQELGGP -DGFENVLRKIGDHVTEADRYETDLNSAIPGDIRDTSTARALATNLKALTVDGVLPHDKRT -LLTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR -DTEDAAYDNELIARAAKVTLTAf ->[subseq from] GIL family class A beta-lactamase n=1 Tax=Citrobacter TaxID=544 RepID=UPI000BBD050A --pTTLNKVKEAESVLPARVGYAELDLISGEILeSYRLQERFPMMSTFKVLLCGAVLARVD -AGKERLDRRIPFSRRDLVEYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLTAIGGP -QGLTAFLRTTGDRVTRLDRWEPELNEALPGDKRDTTTPENMAQTLRQLLTGKILTTTSQQ -QLTHWMVTDKVAGPLLRSVLPAGWFIADKTGAGARGSRGIVAALGPDGKPSRIVVIYITE -SQATMEARNRQIAGIGATLIQHw ->[subseq from] Beta-lactamase n=3 Tax=Rhizobium fredii TaxID=380 RepID=A0A0T6Z3T6_RHIFR ---DVTELLAELEKRTGGRLGVAVLDTETNTSF-GYRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGEMTIAELCDAAITISDNAAGNLLLESFGGP -AGLTSWLRSIGDEATRLDRTEPDLNEARFGDPRDTTTPAAMIGTLGKLAFGSVLSESSRQ -QLIEWMVANTTGDARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPESRGPILIAVYTGE -AKLRPAELNPIFAEIGRIVA--- ->[subseq from] Class A beta-lactamase n=3 Tax=Rhizobium fredii TaxID=380 RepID=A0A2A6LX54_RHIFR ---DVTELLAELEKRTGGRLGVAVLDTETNTSF-GYRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGEMTIAELCDAAITISDNAAGNLLLESFGGP -AGLTSWLRSIGDEATRLDRTEPDLNEARFGDPRDTTTPAAMIGTLGKLAFGSVLSESSRQ -QLIEWMVANTTGDARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPESRGPILIAVYTGE -AKLRPAELNPIFAEIGRIVA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000472BBC5 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A366ES13_9BACI ------HKFMQLEKKFDARLGVYAIDTGTNRTV-AYRPDERFAYSSTFKALAAGLVVQQNS ---MDELDEVITYTRDDLVTYSPITEQYVDTGMTLREISDAAIRYSDNTAGNLLLQELGGP -DGFENVLRKIGDHVTEADRYETDLNSAIPGDIRDTSTARALATNLKALTVDGVLPHDKRT -LLTDWMRGNTTGDELIRAAVPKGWEVGDKTGAGGYGTRNDIAIVWPPNRDPIIIAILSSR -DTEDAAYDNELIARAAKVTLTAf ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. (strain Marseille) TaxID=375286 RepID=A6SVG3_JANMA ---TAQEELKRIESAARGRLGVSALNMANDNRV-EYRAEERFPLCSTFKVMVAAAILQRSA -SEAQLLQKRIRYKKDQVEKYAPVTQKHLADGMTIAELCAATLQYSDNAAANFLMTELGGP -AAVTAYMRSIGDDVFRLDRWEPELNSAIPGDERDTSTPAAVERSLEKIALGNALANPQRE -QLVSWLKGNTTGSKRMLAGVPRGWIVGDKTGTGSYGTTNDAGILWTAKGTAIVAAIYFTQ -NDKDAAAREDVIAAATRIVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BF308D4 -------SFIKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000568C149 ---EIDRRVGELEKRIGGRIGVSVIDTETNISF-GHRETESFPMCSTFKVLAAGLVLARVD -KGQENLERRIVYNKDKLVTYSPETEQHVGGEMSVGELCKAAITLSDNTAGNLLLESLGGP -KELTNWLRTLGDGSTRLDRWETDLNEAKKGDQRDTTTPDSMLDTLGNLALGSVLSEPSRN -TLIEWMVANTTGAARLRAGLPDSWKIGDKTGTGNNGTAADIAIAWPPGHGPVLVTTYVAE -AQVPVSEINPIFAEVGRIVTE-- ->[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium sp. Panama TaxID=2161826 RepID=A0A2T5NIF4_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ -AKPGLLDKRIRYSKTTLPNWSPITTKNQANGMTVAELNAASVQYSDNGAANLLLEEINGP -AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESMQKLTLGKVLPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWDVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus siamensis TaxID=480071 RepID=UPI000987D2EF -----DEKFAQLENEFDARIGVYAIDTGTKQTV-AYHPNERFAYTSTFKVLAAAILLKQND ---IQELERVIPYTKDDLVTYSPVTEKHVDDGMTLLEISEAAIRKSDNTAGNLLLEAIGGP -DKFEQALRNIGDDVTQPERYETELNEFKPGNKRDTSTPKAMAANLKKVALSDFLSKNKRE -LLIDWMKGNATGDALIRAGAPEGWKVGDKSGAGSYGTRNDIAIVWPPNREPIVIAVMSRH -NKEDAEYDDALVAKAAEITL--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas mosselii TaxID=78327 RepID=A0A1X1P3L1_9PSED -hdPLRQAMQQLEAASGSIIGLWALDTGSGRQL-AWRGEERFAFCSTFKAVLAGAVLHHNE -AEPGLLARRIAYGAEQLVVYSPVTEKHVGPGMTVAELCAAAVQYSDNTAGNLLLELVGGP -PGLTAFVRGLGDPTFRLDRNEPTLNTALPGDPRDTTTPLAMGVTLQRLLLTDGLPAGAQQ -QLQAWLKGNTTGDARIRAGLPKDWVVGDKTGSGDYGVANDVAVIWPKGLAPWILVVFSRG -TKQDAPWNSETIAAATRIVVEAw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5C2D2V6_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELEPNSTIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium amazonense TaxID=1382803 RepID=A0A2S9X8A1_9NEIS ----ADQKIARLERVFGGQIGVYALDTGSGAAV-SYRADERFPLCSSFKGFLAASALAHSQ -SKPGYLDQILHYGKEELIAWSPISEKHQSSGMTVAGLCAATVQYSDNAAANVLMKQLDGP -AGLTAFMRAIGDSTFRLDRWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAHQRQ -QLVDWLKGNTTGNQRIRAAVPAGWSVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA -SKKDIKHSDAVIADAAKAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243G2D4_BACTU ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTRKDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] BETA-LACTAMASE n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI00001130B4 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5Z9Q5_9BACT ---DFANRIRSIEQRTGARIGVTALDTGSGKGI-DYRSEERFPMCSTFKFLAAAVVLKRVD -DRQEKLDRFVSYGAKDILEYAPVTKAHLKDGMTLGALCAAAIEQSDNTAGNLLLDTIGGP -VGLTNFVRSIGDEMTRLDRKEPELNSAIPGDERDTTTPAAMCADIQRLVLDNVLSESSRH -QLEDWLRHNETGALMIRAGVPKTWTVGDKTGRCGNGATNDVAIIRPPGRAPVVFAIYSIG -STSSADDRAAIVADAARVVV--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD3BBB ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNTTGDKLIRAGVPTDWEVGDKSGAGSYGTRNDITIVWPPNRAPIVIAILSSK -DEKEATYDNQLIAEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. populi TaxID=487823 RepID=A0A2S6Z7W7_9XANT ----LRAQWAEIERSSGGRLGISLLDTGTGKRI-GQREDERFPMCSTFKFVLAAAVLQRVE -QGRLTLAQRVKIRTADMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAYTRSDRHEPEMNRFALDDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGTDTRNDIAIIWPPAGAPLLLTAYLNG -AKVGDAARDAALKAVAQAVATY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKH5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMVSTFKVLLRGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI0004A137CA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVDGP -AGLTAFLRQIGDNVTRLDRWETVLNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1KNM5_BACCE -hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDWVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRQ -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK -EEKEATYDNQLIAEAAEMIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Actinorugispora endophytica TaxID=1605990 RepID=A0A4R6V530_9ACTN -----EEEFERLEGEFDARLGVYAVDTGTDEAV-AFNADERFAYASTHKAFSVAAVLRQNS ---VEELDEVVTYTEDDLVDHSPVTERHVDTGMTLREIGDAAVRYSDNTAANLLFEELGGP -EGLDAALEEVGDDVTQVDRIETELNEAVPGDPRDTSTPRAMATTLREYALGDALPAGKRV -ILTDMLQGNTTGDALIRAGVPDGWEVGDKTGAGGYGTRNDIAVLWPPHGDPVVLAVMSSR -DAEDAEHDDALIAEAAEVVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4U2TXD5_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKRSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00111D1656 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEIITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMRDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00109411F7 --qTLTSQLEILESKSGGRLGLAVIDTSDGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPVTRKHIGSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRNEPGLNTAIPGDERDTTTPSAMAESLKKVFLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -HDKDAATRKDVLASAAKLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AB9D3E -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---KEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A377QLQ1_9BURK ---AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI0001A5526B ---SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA -SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV -ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMAASMNALVLGDALPAAQRE -QLALWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ -REKDAKPRRDVLAAATKILLSH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A172WCE9_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP -QLLQWMVDDRVAGPLIRSVLPAGWFTADKTGAGKRGARGIVALLGPNTKAKRIVVIYLRD -TPASMAERNQQIAGIGAALI--- ->[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus xylanilyticus TaxID=582475 RepID=A0A0K9F523_9BACI -----IDKFEQLEKKYDARLGVYAIDTGTKKTV-EFREDERFAYTSTFKALAAGAVLQQNS ---IEELNKIVTYTSDDLVTYSPITEKYVDTGMTLKDISEAAIRYSDNTAGNLLFKELGGP -EGFETSLKKLGDQVTNAERIETGLNEAVPGETRDTSTPKALANDLQAYALGEVLTHEKQT -MLVDWLKRNTTGDNLIRAGVPKGWEVGDKTGGGGYGTRNDIAIVWPPNREPIVIAILSSR -DKQDATYNDELIAQASEVVMNVf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00138E6CA7 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYESDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013C94D14 ------PRFAELETTSGARLGVFAVDTGSGRTV-AHRADERFPMASTFKGLACGALLREHP -LSTGYFDQVIHYSAAELVEYSPVTETRVETGMTVRELCDAAITVSDNTAGNQLLKLLGGP -EGFTASLRSLGDVTSRLDRWETDLNTAIPGDERDTTTPAALAADYRALVVGDVLGAPERD -QLKAWLVANTTGATRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK -SEQDAEPDNALLAGATRVVVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. LB(2018) TaxID=2293324 RepID=UPI000E2EE1D2 -hqATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAVLSSK -EEKEATYDNQLIAEAAEMIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CIAT894 TaxID=2020312 RepID=A0A1W6KJG2_9RHIZ --dNVEKRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGEEKLDRRVTYGKDKLVDYSPLSEKHADADMTITELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLVAWLVASTTGGERLRAGMPAEWKVGDKTGTGPNGSFGDIAVIWPPDRGPIVAAVYIAE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus albus TaxID=2026189 RepID=UPI0014195243 --qATHKEFSQLEKKFDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens Y2 TaxID=1126211 RepID=I2C3T3_BACAM -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B07B46 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAAAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobacter sp. SG703 TaxID=2587140 RepID=UPI0014462546 -------RWAAIEAESGGRLGVAVLDTATGQVD-GHRLDERFPMCSTFKWLAASLALQRVD -TGIERLDRRIVVRREVLLSNSPVTEKHVGGDMSIAELCEAAVLVSDNAAANLLLASFGGP -AAITRHARALGDTKTRLDRTEPALNEARPGDPRDTTTPHAMAVALRSALLGTALSDASRA -RLVQWMEAVRTGVDRLRAGVPPGWRVADKTGTGARGSTNDVAVIWPPQRAPLVVTAYLTD -SKADAARRNAALAAAAKEAV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1S9TUL5_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4X4H6_BREBE ----MDIKFAALEKQFGARLGVYAIDTETDLAV-AYRQDEQFAFASTYKALAAGAVLHQKP ---LEELNKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTKSERYETELNEAKPEDLRDTSTPKALATSLRAYTVGNALSSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWIVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI000C19A6DF ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALISEAAKAALD-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-29 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A288UKE4_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000B45220C -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D725277 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMQGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE3E9D2 ---DIEKQLAALEKRTGGRLGVYVLDTKTKVTF-AHRPDERFAMCSTFKALAAAFVLARVD -KGEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVGELCAATVTYSDNAAGNLLLASFGGP -KGLTDWLRSIGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLLEDVLSPGSRD -QFSAWLVANTTGDRRLRAGLPKGWIIGEKTGTSGRGEAGDIGFMRPSEGNTILASVYIAE -GKKKTKELEPVFAEVGKLIA--- ->[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=R7Z7I5_LYSSH ---TTMEKFEQLEKEYDARLGVYAIDTGTKKIV-EFREDERFAYTSTFKALAAAAVLQQNS ---IEELNKIVTYTSNDLVTYSPITEKYVDTGMTLKDISEAAIRYSDNTAGNLLFKELGGP -EGFETSLKKLGDQVTNAERIETGLNEAVPGETRDTSTPKALANDLQAYTLGDVLTHEKQT -MLVDWLKRNTTGDNLIRAGVPKGWEVGDKTGGGGYGTRNDIAIVWPPNREPIVLAILSSR -DKQDANYNDELIAQATKVVMNVf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A0D0QU86_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKITLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A150B9E0_BACCE -----YKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMSDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALSDHKRN -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIVAILSNK -DEKEAIYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF81ACA -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia coubleae TaxID=356147 RepID=UPI00083120DB ------TQYATLESKYSARLGLSVTDTGTGATV-AYRADERFPIASTFKGLACGALLKAHP -LSTGYFDQVIHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP -AGFTAFLRTLGDNVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAEPERT -QLADWLKANTTGGKRIKAGLPADWTVGDKTGSPAYGSALDVAIAWPPNRPPLVLAVLSTK -SEQDAEPSNELLAEATKAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD8ABDC --------FVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q2YHX6_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaTWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1N6VH18_BACCE -----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTATNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia rohdei TaxID=29485 RepID=UPI000B70AFF4 ---SLDKQLAELEQQSQGLLGITVINTGNGRKI-QYRGTQRFPFCSTFKFILAAAVLNKSA -SQPKLLDKHLHYHERDLLSYAPITRKNLAHGMSVSQLCAATVQYSDNTAANLLIQELGGV -ESVNQFARSIGDQTFRLDRLEPELNSALPNDPRDTTTPSAMANSMNALVLGDALPAAQRE -QLALWLKGNTTGGETIRAGAPAEWIVGDKTGTGDYGTTNDIAVLWPTKAAPIVLVIYFTQ -REKDAKPRRDVLAAATKILLSH- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J8R4H6_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPKLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243N7Q8_BACTV --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=A0A328AQU5_9CAUL -----APSFTMLEARSGGRLGVHAVNLVTGKRL-AHRADERFAMCSTFKALAAAAVLARVD -AGQERLDRGVPITRADMRPHAPVTETYLDRGVSLEALCKAAVEQSDNPAANLMLKTVGGP -EGLTAWLRGIGDRATRLDRWETELNSAIKGDPRDTTTPAAMTATLGKLAVGEVLKAASRE -KLVGWMIASPTGANRLRKHLPAGWRAGDKTGTGANGSTNDVAVFWPPTGGPIVVACYITE -TSAELAVREGVMAEVGRIVAQ-- ->[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI001407F418 -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -AKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLEEINGP -AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESMQKLTLGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDYAVIWPPKRAPIVLTVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CCGE532 TaxID=2364272 RepID=A0A387GND0_9RHIZ ---DVDKQLTDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATASAKDVEAVFAEVSKIVT--- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0011DC992D ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLPAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A36DE8A -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6AEG0_9BACI -hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD67A5A --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGKDKLVTYSPETEKHAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRTETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAVIWPPKRGPIVAAVYIGE -ATVKVDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011A7D318 --qATHKEFSQLEKKYDARLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITFMKEDLVDYSPITEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDNRDTSTAKAIATNLKSFTVGNALPVHKRY -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPDRAPIIIAILSSK -DEKDAPYDNQLIAEATEVIVN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCD4_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP -QLLQWMVDDRVAGPLIRSVLPAGWFTADKNGASKRGARGIVALLGPNNQAKRIVVIYLRN -TPANMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-920 TaxID=1463921 RepID=UPI0004C8B3A3 ---DARRRLRELEKGYPGRIGLHALNTGTGATL-GYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDTVIRYGRDDLVTYSPRCEMHLATGMTVRELCDATITYSDNAAGNLLMRRIGGP -SGITRFARSLGDPHTRLDRWETDLNTNIPGDPRDTTTPAAMTANLRKLVLGDALAPLDRD -QLIRWLVENTTGDKRIRAGLPEGWRVGDKTGSPAYGGINDVAVAWPPKGAPLVISVYTTR -LDPDTPGEDRIAADMTRIAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0008FE5329 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGALLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=2 Tax=Prauserella muralis TaxID=588067 RepID=A0A561FK76_9PSEU ---EHERALRQLERRFGARLGVVAEHTGTGRTL-RHRPAERFAMCSTFKVLAAAAVLRRSE -DERRLLRRRIGISAADLVPYSPVCERYAGSGLTVADLCEAAVSHSDNTAANKLLELVGGP -RGVTALAHAAGDTVTRLDRVEPDLNSAVPGDPRDTTTPANIAATYRALVLGDVLAAPGRE -RLRAWMLATTTSADKMRAGVPESWRVADKTGSGGYGTGNDVGIVWPPSGSPLVIAVLSTR -GERDADADPALIAEVTTIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8R2N8_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. LK2 TaxID=1628206 RepID=A0A0J6KWS9_9BACI ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI0005372474 ---AAQTQLAALEKAAGGRLGVAAWRQGSDLRI-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI0011EB3E20 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000DE1CE69 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAETAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8PZ17_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -RGYEKALRQIGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNTTGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPQNRAPIVIAILSSK -DEKEATYDNQLIAEAAEVVID-- ->[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-44 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4Y5JTU1_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAV------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF4A610 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTDPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. BJB446 TaxID=2048009 RepID=UPI000C109AC9 ---AAQAQLAALEQAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000F5277D1 -----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTRGDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEEMGDNVTNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPFVLAVLSSR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002EE964D --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_8 TaxID=1969377 RepID=A0A328L4S0_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIITILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A329YJ80_RHITR ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGTEKLDRRVIYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTAWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPILVTTFVAE -ATASAKDIEAVFAEVSKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9T8H5_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00066531A5 --qATHKEFSQLEKKFDARVGVYAIDTGTNQKI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI0013D52160 ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLANGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BDRD-ST196 TaxID=526976 RepID=C2SKH1_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1S9YQW4_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium currus TaxID=2051553 RepID=A0A2R4WJE4_9RHIZ ---DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAVAAAAVLARAD -EGQDDLNRRITYGSDAVLSYAPVTGKHVETGMTLAELCAAAVVWSDNTAANLMLDTLGGP -AGITAFARAHGDMVTRLDRTEPTLNTAIPGDVRDTTSPAAMVGLLDNILLGRALSARSRA -RLIGWMQDSPTGLKRVRAGLPEGWRTADKTGTGDNGTANVVALIHRPDGAPILAAVYLTG -SPAEPAARDALHAEIGRLIAR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I7ACB5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLXNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQI----------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1K2S8_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVID-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKD1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPIDERDTTMPVAMATTLRKPLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF710A2 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542SHY7_9BACL ----MDIKFAALENKFDARLGVYAIDTETDLAV-AYRQDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLPSDKQT -ILIEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF6A19E -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEDA6B2 ----LRAQWAEIERRTGGRLGISLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGELTLAQRVKIRASDMVEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPDDPRDTTTPAAMAATLRTLLLGNTLQPASRK -QLTDWMIDNRTGDSCLRAGLSRGWKIGDKTGNNGTDTRNDIAIVWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. LX32 TaxID=2170551 RepID=A0A328AKU4_9CAUL ---DATARIRKLETDLGGRIGVSAVDTGSGRRL-GYRAGERFPMCSTFKALAAAAILHRVD -TDCDALDRRILIRKSDPKGWSPVTETHVGQDMTLEALCAAAVCYSDNGAGNLLLGALGGP -AGLTGYVRSLGDKVTRLDRWELELNRVPPGDPRDTTSPAAMQATLAKVALGKALAPASRD -KLVGWLVANTTGDDRLRAGVPKAWKVGDKTGTGDGGGVNDIAVLWPPGRAPIMAAVYTVG -SAKPAAARSAAIAEIGRIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI0004D7B732 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKVRASDMLEHAPVTERHIGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRREPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLADWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNV -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9Q5U3_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000650BEEE ------EQIKISESQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTPPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. MP5059B TaxID=1766683 RepID=UPI000875A1CE ---AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Thermobifida halotolerans TaxID=483545 RepID=A0A399G6J2_9ACTN ---AVDAEFARLEEEFGARLGVYAVDTGTDEVV-AYNADERFAYASTFKALAVGAVLRRNP ---VEELQEVVTYTAEDLVAHSPITEQHVDTGMTLREVCDAALRYSDNTAANLLFDELGGP -EGLEAVLREIGDDVTNVDRIETELNEAVPGDARDTSTPRAMATSLGEFALGGALPGDRQE -ILIDMMRRNTTGGTLIRAGVPQDWEVGDRTGAGGYGTRNAIAVLWPPNGGPVLLAVMSSR -DTEDAEYDDALVAETASVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=A0A2D3TFV0_9ENTR -hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD -AGLEQLDRRIKYRQSDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP -KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILSVKSRQ -QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE -TQATMDERNKQIAEIGASLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011A1A1D6 ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQENS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSERFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWEVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEVAEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG3X2-1 TaxID=1053183 RepID=J7V3D8_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKKDAKYDDKLIADATKIVLD-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B7E69F ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPVSMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBC5A2 ------DSFVKLEKEFDAKLGIYALDTDTSQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium amazonense TaxID=1382803 RepID=UPI0008DADBAA ----ADQKIARLERVFGGQIGVYALDTGSGAAV-SYRADERFPLCSSFKGFLAASALAHSQ -SKPGFLDQILHYGKEELIAWSPISEKHQSSGMTVAGLCAATVQYSDNAAANVLMKQLDGP -AGLTAFMRAIGDSTFRLDRWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAHQRQ -QLVDWLKGNTTGNQRIRAAVPAGWSVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA -SKKDIKHSDAVIADAAKAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar mexicanensis TaxID=180868 RepID=A0A242WGG5_BACTU ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IENLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWKVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A411G932_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIA---------- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B8DIH4_BACTU --qATHREFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D615_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLVRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4B3E2_BACTU ---TVNHSFAKLEKEFEAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTRDDLVNYNPITEKYVDTGMTLKELSDASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. RA13 TaxID=1502762 RepID=UPI0005634609 ---AAQAQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTMFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas dyei TaxID=743699 RepID=A0A2S7BYT2_9XANT ----LRAEWAEIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD -KGELTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP -AGLTAFLRGIGDTHTRSDRHEPEMNRYAEGEPRDTTTPAAMAATLRTLLLGNALQPASRK -QLADWMIDNRTGDTCLRAGLPHDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAAAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BEAF525 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTKDTNYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q84H48_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQQIAGIGAAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000B3494AC ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRTIAYSKEVVVANSPVSGPRAGGDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus khanii subsp. guanajuatensis TaxID=2100166 RepID=A0A4R4JB50_9GAMM ---SLHQQLAELENRTKGRLGVTLINTANGQEI-QYRGNERFPFCSTFKLMLVAAVLHKSM -SQSELLAKHINYSESDLQSYAPIARKNLNQGMNITQLCAATLQYSDNTAANLLIKELGGL -KAVNRFAQGLDDRAFRLDRWEPDLNSAIPDDPRDTTTPAAMATSVKKIVLGETLAAPQRE -QLVVWLKGNTTGDASIRAGTPDGWVVGDKTGGGDYGTSNDVAVLWPPEGSPVVLAVYFTQ -HQKDAESRRDVLASTTRLVMEH- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A371UVI5_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS075960 TaxID=2034282 RepID=A0A2B4P2W8_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCD424 ---DVDKQLADLEQKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVSKIIVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar zhaodongensis TaxID=180896 RepID=A0A243M3Z7_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0013C1D463 ---NIEHRLAALEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARGD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAILDTLGNVTLGSVLAEASSD -RLIAWLVASATGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI0006C546F1 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRN -ILTKWRKGNATGDKLIRAGVPTNWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSNK -KEKGATDDNQLIAEAAEVIVNAf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces xinghaiensis TaxID=1038928 RepID=A0A3M8EUT1_9ACTN ---EVSRRLRALESEHGARLGVFARNLDTGETV-VRRADERFPMCSLFKPVAAAAILRDHD -RNGDFLARRIRYGTTDLVDHSPVTGKHVAQGMTVGELCDAAIRFSDNTAANLLLRELGGP -RAVTRFCRSVGDRTTRLDRWETELNSAEPWRVEDTTSPRAIARTYTRLIVGDALPPADRE -RLTDWMLANTTSDERFRAGLPAGWALADKTGGGHYGTNNNAGVAWTPDRTPIVLAVLTTK -PAPDAAPDNELIAKTAELLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEDBB03 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8ESS1_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1BRF5_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q93LJ5_PROMI ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGASERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEI-------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFCDB51 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGL -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B2LG81_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGL -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI000BAC8D12 --qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPITRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRNEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -HDKDAATRKDVLASAAMLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012EAED63 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -VLTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEBDDB0 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00094307C4 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M824_9BURK ----WRSALQAVESTLGGRLGVAMLDTATGRAL-GWRQDERFPMASTFKLVLAGWMLERVD -RGQESLTNRVQYERSALVPYSPVTEKHTGAVMTVGELCEATVTLSDNTAANLLLARHGGP -AGFTAFAQSLGDTHTRLDRTEPTLNEAAPGDPRDTTTPFAMLHTLRKLVLGDALSPASRA -QLTQWIVDNKTGDKRLRAGVP-GWKVGDKTGTGALGSSNDIGVLWPPAGAPVLVTCYMTG -VPAAPEVRDAAIAQVARHVA--- ->[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3KWS0_9BURK ----WRTALKAIESTLGGRLGVAMLDTGTGRAL-GWRQDERFPMASTFKLVLAGWMLARVD -EGQESLQNRVRYEHSALVPYSPATEKHAGANMTVGELCEATVTLSDNTAANLLLARHGGP -AGFTAFTRSLGDAQTRLDRTEPTLNEAIAGDPRDTTTPMAMLHTLRKLVLGDALSAASRM -QLTQWIVDNKTGDKRLRAGVP-GWKVGDKTGTGANGSSNDIGVLWPPGGAPVLVTCYMTG -VPAAPEVRDAAIAQVAREVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4U2XCJ7_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-TYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A402GGN1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNA ---MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009423289 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLQYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009AFB425 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00061E08F2 -----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTRGDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEEMGDNVTNPERFEPDLNEVHPGETHDTSTPKALATSLQDFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q9S534_KLEOX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF7F746 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009E46493 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Leaf160 TaxID=1736280 RepID=A0A0Q5M5W3_9BURK -----QAALGAVEAGLGGRLGAAMLDTGTGRLL-SWRGDERFPMASTFKLMLAGWMLERVD -RGQESLAQRVRYERDALVPYSPVTEKHVGADITVAELCEATVTLSDNTAANLLLARHGGP -EGFTGFARSLGDAVTRLDRTEPTLNEALPGDPRDTTTPVAMLHSLRTLVLGQALSPASRA -QLTEWIVNNKTGDKRLRAGVP-GWKVGDKTGTGSNGSSNDIGVLWPAGGAPVVVTCYMTG -VPASPEVRDAAIAQVARHVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. UMTAT18 TaxID=1565146 RepID=A0A0F5RXC1_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKVGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter vibrioides OR37 TaxID=1292034 RepID=R0E6D7_CAUVI ---SLSLRINALEKRGGGRLGVAVLDTQDGRRF-AARGDERFLMCSTFKMLLAGLVLRRVD -QKRERLDRRVQYGPEVLVDYSPETKKHVGPGMTIANLCQAVITLSDNTAANLLLDAVDGP -VSVTRFARALGDPVTRLDRIEPALNTARPGDLRDTTSPKAMLETLRTLTVGDALTAESRA -RLVGWLVANQTGDARLRAGLPKTWKIGDKTGSDGRHTTNDIAVIWPPGRAPLLITTYLTG -AKLDDEGRDAVLADVARAVV--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI00124E1FFC --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Alkanindiges sp. H1 TaxID=1907941 RepID=A0A1S8CWW5_9GAMM --qQVSQFLAQLEAQSHGRLGVSAINTANQLRI-DYQANQRFPLCSTFKLVAVAAILHQSM -RDPSVLQQRIQYSMQQVNDYAPITAQHVDSGMTVSELCAACISYSDNTAANLLLHILGGP -AALTRFTRSIGDEVFRLDRWEPALNTAIPNDTRDTSTPAAMADTLQRLLVGNVLAPTQRE -LLLYWLKNNTTGNSRIRAGVPKDWVVGDKTGTGAYGTSNDVGILWPAQQQPIILAIYFTR -PEKTAKPYDEVIAAASRIISQ-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164MBV5_9NOCA -----EAEFASLETEYDARLGVYALDTGSGRIV-AHRADERFPYASTVKSLAAGAILRSLP ---PGALDERLTYSRADLVSGSPVTEKHVDDGMTLREAVDAAVRYSDNTAANLLFAKLGGP -KGLQQNLRDLGDTVTQVDRTEPDLNEATPGDPRDTSTPTAFAADLRRYVLGQALADPARA -LLTDMLRANTTGAELIRAGVPAGWVVGDKTGLASYGSRNDVAVLWPPNAAPIVLVVFTTR -PDKDASYDNALIAKAAAAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. SG-MS1 TaxID=2023741 RepID=UPI001445C8E6 ---AIRERLARIEAASGGRLGVSIVDTTTSLHA-GLRADERFPMCSTFKLLAAGAVLTRVD -HGQEDLQRRVVFSASDLVPNSPGTRELTGDAMSIGELCEAALTLSDNTAANLLLASFGGP -AAVTAFARSLGDGITRLDRIEPALNEAIPGDPRDTTSPNAMLGNLRELVLGEHLSAASRA -QLLAWLAANQTGGSRLRAKLPEDWGVGDKTGTGERGTANDIAILWPPGRGPVLVTVYLTE -TDGDAARSNAAIANVGALVAE-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI000665DA7D ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAINMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRRLLTTPSLSARSQQ -LLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Raoultella terrigena TaxID=577 RepID=A0A3N2DWT7_RAOTE -heATVKQVKAAERLLEARVGYVELDIASGRLLaSYRPGERFPMMSTFKVPLCAAVLARVD -AGEEQLDRRVRYRQHDLVEYSPVTEKHLADGMTVAGLCAAAITLSDNTAANLLLASVGGP -QGLTAFLRRSGDQTSRLDRWETELNEALPGDARDTTTPQAMAKTLRNLLSGSVLSAASRQ -QLRNWMVDDKVAGPLLRSALPHGWFIADKTGAGNRGSRGIIAALGPDGQPARIVIIYLTG -TEASMEERNLQIAEIGETLVKHw ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas wuyuanensis TaxID=1073196 RepID=A0A286CYI4_9GAMM ---ALPKRLRAIEKDSGGRLGVAVLDSGSGQQA-NWRGDERFAMCSTFKFLLAAAVLARVE -KGEEALERRIPILASDLVSHSPVTEKLVGGEASIAQLCEATMIVSDNAAANLLLPLVGGP -EGLTRFVRTLGDTRTRLDRTEPSLNSAIPGDPRDTTTPLAMLHSMQRLLLGDALADASRQ -QLLVWLRGNLTGDNRLRAGLPAGWQAGDKTGTANNGTSNDIAILWPPGRAPLLLTCYLTE -SPLASAARDGIHKAVAAAVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D04D5C ---EIDRRIGALEKRIGGRIGVSVIDTQTNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYDKAQLIDYSPETEKHVGGEMSVGELCKAAITLSDNTAANLLLETLGGP -KELTNWLRTLGDGSTRLDRIEPDLNEAKKDDPRDTTTPDAMLDTLGNLTLGTVLSEPSQN -TLVEWMVANTTGSERLRKGLPDGWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYINE -ATATTDEINPVFGEVATIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A9A5E5_BACCE ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKSDDKLIVEATQIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea sp. JKS000250 TaxID=1938795 RepID=A0A2V3SE58_9GAMM --qTLTSQLETLENKSGGRLGLAVIDTSDDSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPVTRKHIGSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRHEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -HDKDAATRKDVLASAAKLVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=C2PFA6_9BACI ---AMYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-31 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5C0DL16_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DHOM06 TaxID=2291023 RepID=A0A3D8JVH4_9BURK ---AIESESASIENGVDGRLGVAIQDLETGLQA-GHRSGESFAMCSTFKLMLAASVLARVD -RREEDPERRIVYGADQLDEYAPITRENVGGQMTVGALCDAAVAMSDNTAANLLLETIGGP -PGFTAFMRQLGDTVTRLDRTEPSLNTAIPGDVRDTTTPAAMLGSMRKVLLGDALSAVSRA -QLLAWAVGNRTGATRLRAGVPRGWRVADKTGSGERGTTNDIGVLWPQDRAPILVTVYLTE -TRADLRAREGAIAEVARAISR-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus alvei TaxID=44250 RepID=UPI0009D9DFB3 --nQAHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYTSTFKALAAGVLLQKNE ---IEQLDKVITYTKDDLVEYSPITEKHVHTGMTLGELAEAAVRFSDNTAVNLFLKELDGP -KGFEKALRQIGDQVTHADRYETELNEATPGDIRDTSTPQALADDLKAFTVGNALPADKQN -LLMNWMRGNATGDKLIRAGVPIDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR -DKKDAAYHNELIAEAAKVTMK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00035F908C ------DELRALERRYGARLGVYAHNVRTGQTV-AHRAQERFAMCSTFKTVAAAAVLRDQA --HCAPLDKVIHYPAADLVPYSPKTKEHVDSGMTVGDLCAAAIQYSDNTAGNLLLRQIGGP -AGLTRFFRSIGDPVSRLDRWEPDLNSARPGDLRDTTTPEAIGRSYGQLTVGRALAADDRE -RLVDWLRGNTTSAQRFRAGLPHRWVVGDKTGTGDYASANDVGVAWTTRKTPIVLAVLTSK -TSKDAPVDDALIADAARIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Burkholderia verschuerenii TaxID=242163 RepID=A0A0L0MG07_9BURK ---AIEHQFASIESETGGRLGVAILDTASGTHY-AYRANERFPMCSTFKFLLAAAILERQD -RAEESLDRRIAFTKDDVVANSPVSGPRAGGAMTVAELCEAAITRSDNTAANLLLASIGGP -TALTAFARQIGDRTTRLDRIEPALNEAIDGDLRDTTTPSAMLTDMREILLSQRLSSSSRD -RLVAWLVANQTGGTRLRAGLPSNWRIGDKTGTGEQGTANDIAIVWPTGRAPILVAAYLTQ -AVAAPAQRDAAFRQIGALAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BEE73C0 --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000CCBEAD0 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNA ---MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8ZPJ0_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYGDKLIAEATKIVLD-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-41 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5B7LI76_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8B9F7 ------DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDAGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVYPGDVHDTSTPKALATSLQAFALGGVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2J9D765_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWAVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009D2B693 --qATHREFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEVAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY4_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLADLSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPXVLVTYFTQ -PQQDAK----------------- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0S3BXC1_BACTU -----NDSFAKLEKKFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEMYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKKNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS073361 TaxID=2033511 RepID=A0A2B2BUP8_9BACI ---HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPQERFAYASTYKVLAAGALLQHYS ---IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLKKLGGP -EGFETALRQIGDNITQVDRYETDLNSAVPGDTRDTSTPKALAASLKAFAVSDLLPAEKRT -ILTDWMWGNTTGDALIRAGAPTGWEVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAVLSKR -DTQNATYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI00061869DC --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKVGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD142 TaxID=718224 RepID=J7X5R0_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAAAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000E2CB1FC ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGCP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0012F8CCEA --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMEGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium tubonense TaxID=484088 RepID=A0A2W4DMA5_9RHIZ ---NAEKQLADLEKKIGGRLGVSVLDTETNISL-GYRETERFPLCSTYKLLAAGFVLSRVD -RGAEKLDRRVTFGKDVLVTYSPVTEKHADTDMTIAELCEAAITMSDNTAGNLLLDSFGGP -PVLTAWLRTLNDTETRLDRKETEVNEAKKGDPRDTTTPDSMLDTVGGLTLGDTLSDASRE -ALAGWMVANTTGGQRLRAGLPTEWKVGDKTGTGDNGSYADVAIIWPADRGPILIAAYVTE -ATAPIADVNTVFAEVGKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8QW79_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKKDAKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA7E86 ---TVNHSFSKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLDGP -SEFKKSLREIGDTVTNPKRFEPELNEVHPGDTHDTSTPKALASSLQAFALGDVLSTEKRS -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPVVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1B1L601_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2V2H3Q1_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI000550E8EF ------RGINALEVRSGGRLGVAVLDTATGKTF-GHRADERFAMCSTFKALVAGLVLKRVD -QGLERLDRGIPYGPGVLVAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLHTFGGP -PALTAFLRGLGDKVTRLDGYEPGLNVVRPGEIHDTTSPSAMLATLRALTLGPVLSPASRQ -QLIAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGIGTTNDIAVIWPPGRPPLLITAYLSR -SPLDNDGRNAVIAEVARLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001428CA57 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. TaxID=1872427 RepID=A0A2E9RJP7_9GAMM ------STVQEIESRLNARVGIAMSDQETGRAW-RHHADQRFPLASTFKVLACGALLHKVD -AGDDRLDRMIHYGEADLVTYSPATGEHVDTGMTLGALCEAAITLSDNTAANLVLDAIDGP -AGLTRFLRGSGDNVTRLDRREPALNEATPGDPRDTTTPDAILETLRELLFGDTLTEPSRQ -QLLQWMKDDQVADAQLRAGIPDDWTIGDKTGAGGHGSRAIIAVMWPPQRGPILAAIYITE -TDATLEQRNAAIADIGRALA--- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=A0A2R4JD10_9GAMM --qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPVTRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRNEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -RDKDAATRKDVLASAAMLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia mimosarum TaxID=312026 RepID=UPI00047F147B ---AFEKQLAAIEAQVGGRLGVAMLDTASAHVR-GRRMHERFPMCSTFKLLLASAVMARKD -HGEEDLARRVVYSPAQVVSYSPVSGSRAGGEMTVAELCEAALTRSDNTAANLLLESVGGP -SAITAFARGLGDPLTRLDRNETSLNEAIPGDPRDTTTPAAMVANLHELLLGERLSAASRE -QLIAWLVANETGDARLRAGLPKEWRVGDKTGTGDRGTANDIAIVWPTGRAPILVATYLTG -ATASSAQRDAAIAKVGACMA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI000D327A77 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVVIN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009BB9B5B ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVVIN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0U2SP59_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. JFL15 TaxID=1679193 RepID=UPI0012E13B9A ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPGRAPIVLAILSNR -FTEDANYHNALISEAAKAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. melhusii TaxID=487834 RepID=A0A1T1P937_9XANT ---MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQRDDERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG -AKVDDAARDAALKAVAVAVH--- ->[subseq from] BBI family class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D8A259 ----MDIKFAALEKQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDGVTKSERYETELNEAKPEDLRDTSTSKALATSLRAYTVGNALSSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium erythrophlei TaxID=1437360 RepID=A0A1M7UV24_9BRAD --eKLSRNFAELEKERGGRLGVAVADTQNGNSA-VYRGDERFPICSTFKTLAVAALLARVD -AGQERLDRRLRFEAKDVVVYSPVSKNRAGGEMSLAEICEAAITLSDNTAGNLLLANLGGP -EGLTAYMRSLGDTVTRLDRNEPDLNEALPGDVRDTTSPFAMLSDLRTLVIGNALTAASKE -RLVGWLVGNKTGDARLRAGFPRDWRVGDKTGSGEKGTANDIAVVWPSNRSPLFVSVYLTG -GSPEADHRNATLAAVARLVA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001298A475 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEVTEVIVK-- ->[subseq from] class A beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011A9B347 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKRSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF5E9B6 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELAAASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. N35-10-4 TaxID=1866315 RepID=A0A1J9TDQ7_9BACI --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGS -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus sp. CM-4 TaxID=1354277 RepID=UPI0003887512 --tEIKDRFQSLEDEFDATLGVYALDMGTNESI-AYRSDERFAYTSTHKVLAVGALLQQKS ---IAELDERITYTNDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAANLIFNQIGGP -SGLKKVLRNIGDDVTDPQRIEPALNDFTPGEPADTSTPKALVNSLQAFTLGDALPKEKRL -LLMDWMKRNTTGDHLIRAGVPDDWEVADKTGAGSYGTRNDIAIIWPPEGDPIVLAILSKR -DQKDAEYDDKLIAETTKAVIDH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI0003F97F41 ---NIEHRLATLEKRTGGRLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARTD -KGEENLDRRVNYGKGKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTNWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAILDTLGNLTLGSVLTETSSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0012E0E7F8 ---DLDETFATIESEYDARVGVYAIDTGSDQTI-DYRSEERFAFASTYKALAAALVLKQNT ---MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGDQLTDDKRE -RLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH -DTEDAEYDDALIAEVAEATLN-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=I6ZFS9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. TER-1 TaxID=2499852 RepID=A0A437NXE9_9RHIZ ---DAADALAALERKDGGRLGVAVLDTGSGRRL-EHRAGERFPLCSTFKAVAAAAVLARAD -AGEDSLERRIAYGPGDLLDYAPVTRERVREGMSLADLCAAAVVWSDNTAANLMLATFGGP -EGLTAFIRRQGDAVTRLDRTEPTLNEAAPGDPRDTTSPTAMVGLLGRLLLGDALAPASRE -RLIGWMVASPTGAKRLRAGLPPDWVVGDKTGTGENGTANVVALVRRPNAAPLLAAVYLTG -SPATPDARNALHAEVGRLVAATf ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira lucentensis TaxID=168935 RepID=A0A154L2A3_9PROT --dRLTDAIHAVETRLDARVGVSILNVENGREW-QYRADERFPLTSTFKLLACAAILHKVD -LGTETLDRRIIYGVEDLVTYSPTTEKHVDSGMTIGELCEATLHLSDNTAANLILDALGGP -DELTAYLRDIDDDVTRLDRIEPDLNTAKPGDPRDTTTPDAMRASLAYLLLGDALSADSRQ -LLEDWLTGNQVSGPLLRAGLPDDWKIADRTGAGGFGSRAIVAVIWPPEQKPVIVAIYITQ -TSASMDERNAAIADLGQEIA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8HNT0_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTNFTQ -P---------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. NBRC 111133 TaxID=1661048 RepID=UPI000761399F ---SLQHEFSALERSLDVTLGLWAHDTGTGKTL-SYRAEERFAFCSTFKVVLAAAILAKSS -ADKGLLERKISYSEDDLVTYSPVTERHLANGMTVSELCAATLQYSDNTAGNLLLEQIGGP -AGLTDFARHVGDASFRLDRTEPELNTALPDDPRDTTTPLAMGVTLQKLLLGNSLPEGARR -QLQEWLKGNTTGDKRIRAGVPQGWAVGDKTGSGDYGVANDVAVIWPSGKAPWVVTIFTRG -QRKESPWNNEIISS--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1X6Q8Q5_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1ZT22_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIVEAAVRSSDNTAGNILLNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKEDTYDNQLIAEAAKVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=B5D625_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0004974B7D ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7UMZ3_9BACL ---AMDQKFAALENKFDVRLGVYAIDTDTNLAV-AYREDERFAFASTYKALAAGAVLHQKS ---LEELDKVISYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQIGDDVTTSERYETELNEAKPEDIRDTSSPKALATTLRAYTVGDVLSSDKQT -IITEWLQGNTTGDKLIRAGVPKDWKVGDKTGAASYGTRNDMGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF5B019 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD52FC1 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTVAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGSNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVGKIIVD-- ->[subseq from] Beta-lactamase n=7 Tax=Bacillus cereus group TaxID=86661 RepID=R8K5S2_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B4XIS2_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8R6_9BACT ------------EDQLGARVGYTELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC41MFS5 TaxID=1449046 RepID=UPI000479B864 ---QIHREFAELENKYDARLGVYAIDTGTHRTV-SYRPKERFAYASTYKALAAGALLQHYS ---IEQLDQLVTYKSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -EGFETALRQIGDNVTQVDRYEPDLNSAVPGDTRDTSTPKALATSLKAFAVSDLLPNEKRK -ILTDWMWGNSTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DAQNATYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001145EF16 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD666F4 --eDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -RGDETLDRRITYGREKLVTYSPETEKHAGGEMTLAEICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN -RLVDWMVANTTGAARLRAGLPRDWRIGDKTGTGDNGAAGDIAIIWPPGRGPIVAAVYMAE -TTVKMDEFNPVFAEIGRMIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. THG-D6.12 TaxID=2484251 RepID=UPI00130331EB ---AINQKFVHLEKKFDARLGVYAIDTGTKRTI-AYRSDERFAYASTYKVLAAGVVLQQNS ---IDRLDEVIHYSKDDLVSYSPITEQHVDTGMTLKEICDAAIRYSDNTAGNLLLEKLGGP -KGFEKSLREIGDTITRSDRFETELNEATPGDLRDTSTPKALAKSLKAFTVNNVLPSDKRR -ILTDWMRGNTTGDKLIRAGAPKGWAVGDKSGAGSYGTRNDIAIVWPPHKKPIIIAILSSH -KTKDATYNDELIENAAKVALNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AC9819 ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. Marseille-P3787 TaxID=2079532 RepID=UPI000D0E6D83 ---AIESSFVQLEEEYGAKLGVFAIDTGTGRSI-AYRPDERFAYASTYKALAAGLILMNSS ---ADELDQVITYTKDDLVSYSPVTEKHVKTGMTIRDICEAAVRYSDNTAGNVLLKKLGGP -EGYEKALKQIGDQVTQADRYEPELNEAVPGDTRDTSTPRSLATTLSSFIVGNVLTDDKRS -ILIDWMSGNATGDELIRAGAPKDWKVADKSGAGNFGTRNDIAIVWPPNGSPIIVAIMSNR -DVQDADYDNALIAQAAKVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2A7Z2E8_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKKDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus massiliensis TaxID=1462526 RepID=A0A024Q8U8_9BACI ---EIKDRFQSLEDEFDATLGVYALDMGTNESI-AYRSDERFAYTSTHKVLAVGALLQQKS ---IAELDERITYTNDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAANLIFNQIGGP -SGLKKVLRNIGDDVTDPQRIEPALNDFTPGEPADTSTPKALVNSLQAFTLGDALPKEKRL -LLMDWMKRNTTGDHLIRAGVPDDWEVADKTGAGSYGTRNDIAIIWPPEGDPIVLAILSKR -DQKDAEYDDKLIAETTKAVIDH- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3U3T8_BACCE ---ATYKEFSQLEKKFDAQLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRFSDNTAGNILFNKLGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKEDTYDNQLIAEAAKVVIN-- ->[subseq from] Beta-lactamase n=2 Tax=[Polyangium] brachysporum TaxID=413882 RepID=A0A0G3BG19_9BURK ----FEAQCKALEAEVGGRLGVALLSTSTGVSA-GYRADERFPMCSTFKWLAAAYLLSRVD -AGMERLDRRIGYGSNVLIDHSPVTSQHVAGGMTLAQLCEATITVSDNAAANLILDTFGGP -AALTRYLRSLGDNVTRLDRTEPALNHVPPGDERDTTTPAAMTSDLRRLLLGTALSTASRD -QLTRWMLATQTSGTRLRANLPPRWQLADKTGTAN-GTANDVGVFWSPAGEAIALSVYLTE -CRAPAAQQNAAIAEVARWVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00113FA9D1 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMQGNATGDELIRAGAPSGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013D726F3 -------SLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRA -LLTDWLVRNKTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium hainanense TaxID=52131 RepID=A0A1C3UFT2_9RHIZ ---DVDKQLADLEKRTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAAGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCNAAVTLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPDRGAILVTTFVAE -ATAPAKDVEAVFAEVGNIVV--- ->[subseq from] inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-33 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C32FA0F -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus licheniformis TaxID=1402 RepID=A0A1Q9FXS5_BACLI -----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRIAYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEEMGDDVTNPERFEPDLNEVHPSETHDTSTPKALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0007791762 ----MKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas graminis TaxID=158627 RepID=A0A1I0IJV2_9PSED ---AIQQQLADLESRHGGRLGVAILDTASQRLI-SHRGDERFALCSTFKCLAAAHVLARVD -RKQEDLSRRIVYSAEQLVAYSPTTELHVGGQLSVGSLCEAAMTLSDNTAANLLLDSMGGP -EGLTAWLRLIGDTRTRLDRREPDLNENRPQDLRDTTTPVAMLHTLNTLVLGDELTLPSRD -QLTAWLVNNQTGDKKLRAGVSGGWRVGDKTGSGSNNATNDVAVIWPGDRPPILVTAYYTG -SKASADQINAVMADIGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=J9AUM8_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B5LXC0_9BACI -----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPQLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKENAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7X087_9BACI ---ATNREFTQLEKKFDARLGVYAIDTGTNQTI-TYRPNERFAYASTYKALAAGTVLHINS ---MDKLNKVIHYTKDDLVEYSPITEKHVDTGMTLGEIAEAAVRYSDNTAGNLLFKTLNGP -QGFEKALRQMGDKVTCANRFEPELNEAIPGDIRDTSTPKALATDLKDFTVGNALPAEKRK -ILTDWMRGNATGDKLIRAGVPKDWKVGDKSGAGDYGTRNDIAVVWPPNRAPLIIAILSSR -DKKDATYDNELIVQATKVIMN-- ->[subseq from] class A beta-lactamase n=1 Tax=Grimontella sp. AG753 TaxID=2183905 RepID=UPI000D761D1F ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMMSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTLAELCSAAITMSDNTAGNLLLSAIGGP -SELTAFLRKAGDRVTRLDRWETALNEALPGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSPGIVAALGPDGKPARIVVIYITE -TQATMDDRNKKIADIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus alvei TaxID=44250 RepID=UPI0013D9215E --nQAHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYTSTFKALAAGVLLQKNE ---IEQLDKVITYTKDDLVEYSPITEKHVHTGMTLGELAEAAVRFSDNTAVNLFLKELDGP -KGFEKALRQIGDQVTHADRYETELNEATPGDIRDTSTPQALADDLKAFTVGNALPADKQN -LLMNWMRGNATGDKLIRAGVPIDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR -DKKDAAYHNELIAEAAKVTMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007C84394 ---SAQPQFVELERALNGRLGVFALNTADGARL-GYRAEERFPVCSTFKVLVAAGILERST -QIAGLMQQRINYLPSDLVTHSPVTEKHLVTGMTVAELCDAVMRYSDNTATNLLMKILGGP -AGVTDFARSIGDREFRLDRWEANLGTAIPGDPRDTSTPEAMGRSLQRLVLEDALGVRQRK -QLQVWLRSNTTGANCIRAGVPSDWQVGDKTGAGAYGTRNDVAVLWPPHRPPVILTVYSTQ -HEKDAKWREDIIASAARIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1QP29_BACCE ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKAIAAGVLLQKNS ---TEKLNEVITYTKEDLVDYSPVTEKHVGTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTLSDRFETELNEAIPGDNRDTSTAKAIATNLKNFTIGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. KBW07 TaxID=2153358 RepID=A0A3N7CAY0_9BURK ---SAEAQLAALETASGGRLGVVAFNSTSGARV-QHRAHERFPFCSTFKLMLAAAILERSA -KDASLLTRHVNYSKGDIISYSPITEKNLATGMTVAALCAATVQYSDNAAANLLMKILGGP -PAVTAFARSIGDQAFRLDRWETELNTAIPGDLRDTTTPAAMADSVHRLALGDALGTAQRD -QLQAWLLGNTTSTERFLAGVPAGWKVGDKTGSGSYGTTNDVGVLWPPAGAPLVVAVYLTF -PDKDAKGRNDVIASAVRIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / VKM B-1802 / 2st14) TaxID=644282 RepID=E1QJV5_DESB2 ---AAATRLAAIETSLDGRLGLFALNTADGRTL-AHRSDERFAMCSTFKLVLAGAILAQSA -QTPGLLERRVAYGPEALVSYSPITQKHAAGGMTVAALCAAAVRHSDNTAANLLLDQLDGP -AALTTFARTIGDNHFRLDRREPELNTAIPGDPRDTTTPAAMGRSLQRLALGRALPAEGRA -LLCAWLRGCVTGAARIRAGVPAGWVVGDKTGTGAYGVANDVAVLWPAAGPPVLLAIYTAR -RQKDAAPRNDVIVAAAKVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. Leaf131 TaxID=1736270 RepID=A0A0Q5GHU7_9XANT ----LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKLSLAQPVKIRASDMLSHAPVTERHVGGTLSVGELCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTRGWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011560A1A --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. YK2 TaxID=1860096 RepID=A0A1E4Y0Q5_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTVAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRE -QLVNWLVANTTGSNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVGKIIVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Roseomonas deserti TaxID=1817963 RepID=UPI001331BC45 -----PRRFAQIEAARGGRLGVAVLDTGTGRQA-GYRQDERFPILSTYKTLAAAAVLARAD -AGMDSMERRVRFTRDDLVTYSPVTEKHVGQGMTLAALCEAAIVTSDNTAGNLLFDAVEGP -AGLTAWLRTIGDPVTRLDRLETALNEALPGDPRDTTTPAAMVLDLQALALGSVLSSSSRE -RLVAWLRGCRTGDARLRARLPQGWTAGEKTGTGERNSSNDAGLLWPPNGPPVLVAAYLTG -GAADGAVRDAALADIGAAVAE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00080F686C --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKAIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKC1_9BACT ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNGLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGLDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Methylosinus sporium TaxID=428 RepID=A0A2U1SNZ8_METSR ---ELSARVEAIERRAGGRLGVAVLS-GDGRRF-AHRADERFPMCSTFKALAVAAVLKRID -AGALSLERKIAYGQADLLDYAPATRAHVADGMSLRDLCAAAMQLSDNTAANLILGALGGP -QAVTETARSLGDEATRLDRDEPTLNSAIPGDPRDTTTPMAMARDLRELIMGRALSETSRL -LLEDWMIGNKTGAKRLRAGLPPDWGVGDKTGSGENGAANTIAIFRPPRRAPLFVAVYLAE -AGGSKEERDAVHHDVAKSIAETf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A8DZJ2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADRTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIG------- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas pisi TaxID=56457 RepID=A0A2S7CZG5_9XANT ----LRTQWAEIERGTGGRLGISLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGTLTLAQRVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGLTAFLRSIGDAQTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDACLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGLPLLLATYLNG -AKVDEAARDAALKAVAQAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00077A362C -----DDSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAAGALLRQNS ---IEALNERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDATYDDKLIADATKIVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD146 TaxID=1053236 RepID=R8N2P9_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGDWEVADKTGSGSYGTRNDIAIIWPPNKKPLILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] BETA-LACTAMASE TEM n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000181CFD6 ---------------RPCRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGRRGSRGIIAALGPDGKPSRIVVIYTTG -SRKKTDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0004BAFBA2 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNEIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -TLTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BED8499 -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DQEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. A4 TaxID=1225184 RepID=UPI00068758BF --eKIQQQLRQLETQSGGRLGVVLIDSADNSQI-RYRANERFPMCSTSKVMAVAALLQQSE -KNSAVLQQRLAINASDLVNYNPITEKQVGSSMTLAELSAATLQYSDNAAMNLILDHLGGP -GKVTAFAQKTGDRDFRLDRREPELNSAIPGDPRDTTTPLSMAQSLQKLTLCKALAAPQRE -QLVQWMKGNTTGSQSIAAGLPSGWQVGDKTGSCDYGGTNDIAVIWREKGAPLILTTFFVQ -PQPDAKSRRDVLAAAAKIVTAQy ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI0007E5A1C4 --qTLKSQFETLENKSGGRLGVTVIDTSDGSTY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDPGLLDKKIHINKSDMVNYNPITQKHIGSSMTVAELSAAALQYSDNAAMNKLLAYLGGP -QQATRFARTTGDKAFRLDRKEPELNTAIPGDARDTTTPSAIADTLNNLVLGTALKEEQRI -KLSEWMKGNTTGVNSIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIILTTYFTQ -HAKDATARKDVLASAAKLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000F60361E -----NQKFVQLEKKFDARLGVYAIETGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=C3H194_BACTU --qATHKEFSQLEKKFDARLGVYVIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00143694B5 ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAVPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. T12 TaxID=477697 RepID=A0A560WEQ6_9ACTN -------NLTALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAALLDRRP ---GARLDERITYGEADLVPYSPVTEKHTGKGMTVRELCDVAVRYSDNTAANLMLRDLGGP -RALTAYLRGLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVLGDALPGAGRA -QLTDWLVRNTTGDRRIRAGAPRGWTVGDKTGSGEWGRANDAAVLWPGNGSPLVLSVLTER -PDRDAAASDVLVAEAARRVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF9F9AC -----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb209 TaxID=1848605 RepID=A0A2S8UH07_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00111FF7D7 --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDIGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEATPGDIRDTSTAKAIATNLKAFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RE76_9BACT ---EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -VGLTNFARAIGDKVTRLDRKEPELNTAGPGDERDTTTPAAMLADMLQLLLGNTLSPSSRH -QLEQWLQANETGASMIRAGVPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG -STATANDRAAVLAEAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A168W1T2_9BACI ----TAKKFMQLEKKFDARLGLYAIDTHTNRTV-TYRPDERFAYTSTFKALASGLILQQKS ---IDELNEVITYTKDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLKELGGP -NGFEKALREMGDNVTKADRYETDLNSAIPGDIRDTSTARALATNLKSFTVDDELPNDKRE -ILTDWLQRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNREPIIIAILSSR -DTQNATYENELIAEAAKVALDAf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7BWY2_9BACI -----NNSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI00124DE10A ---TVNHPFSKLEKEFDSKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALTTSLQAFGLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDANYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0012D9E646 ------QKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0002458CD5 ------QKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3F332 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALVVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. commiphoreae TaxID=1101443 RepID=A0A3G2W3N9_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=UPI00088523A0 ---ALEKQLAQIEGQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLERKIVYSKDVVVANSPVSGPRAGSDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEALEADPRDTTTPAAMLADMRALLLGEHLSAASRE -QLTAWLAANKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVAAYLTG -ATATSTQRDAAIAQVGVLVA--- ->[subseq from] Beta-lactamase TEM,Beta-lactamase PSE-4 n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00067E6531 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPLTSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CNB394 TaxID=1169151 RepID=UPI0003AB48E6 ------QAFRLLEEKFDARLGVYAIDTGTGRTV-AYRPDERFAYASTYKALAAAEILDETT ---DAELDRVVRYSADDLVTYSPITEQHVATGMTLRAITDAAVRYSDNTAANLMLRHLGGP -QRFERELRGIGDKVTDPERYETELNEARPGDRRDTSTPRALAGSLRAYTVGDALEPPDRA -TLNDWLRRNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDADYDDALIAEATRVVTAGw ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000DEEAF6F ---ALEKQLARIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRTIVYSKEAVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A6B8YMQ4_BACCE -----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Yersinia intermedia TaxID=631 RepID=Q1W758_YERIN ---SLDKQLAALEHSANGRLGIAMINTGNGTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKDANPVPDVL----------- ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=A0A1H6PA63_9BURK ---ALEKQLARIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRTIVYSKEAVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEATEADPRDTTTPAAMLADMRALLLGGHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SRB_28 TaxID=1969378 RepID=UPI000DC30EC5 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus alvei (strain ATCC 6344 / DSM 29 / NBRC 3343 / NCIMB 9371 / NCTC 6352) TaxID=1206781 RepID=K4Z7G8_PAEA2 --nQAHQQFVQLEKKYDARLGVYAIDTGTNQTI-TYRSNERFAYTSTFKALAAGVLLQKNE ---IEQLDKVITYTKDDLVEYSPITEKHVHTGMTLGELAEAAVRFSDNTAVNLFLKELDGP -KGFEKALRQIGDQVTHADRYETELNEATPGDIRDTSTPQALADDLKAFTVGNALPADKQN -LLMNWMRGNATGDKLIRAGVPIDWEVADKSGAGGYGTRNDIAIVWPPNRAPIIIAVLSSR -DKKDAAYHNELIAEAAKVTMK-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0009B99C46 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMLSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVVLLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0008727FD5 ------EQIKXSESQLXGRVGMIEMDLASGRTLxAWRAXERFPXMSTFKVXLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar toumanoffi TaxID=180862 RepID=A0A243E3C2_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVNDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF60933 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFPYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2B1TQ48_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. T33-2 TaxID=2054168 RepID=A0A2N5H4G2_9BACI ---QIVREFAKLERKFDARLGVYAIDTGTHRTV-AYRPDERFAYASTYKALAAGALLKHYS ---IDQLDELVTYKREDIVSYSPVTELHVDTGMTLREVSEAAVRYSDNTAGNLLLKKLGGP -EGFETMLRQIGDNVTQVDRYETDLNEAVPGDTRDTSTPRAIANSLRAFAITDLLPAEKRT -ILTAWMRGNATGDALIRAGAPKGWVVDDKSGAGSYGTRNDIAIVWPPNRSPIVIAVLSSR -DTQNATYDNALIAEAAKAAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHZ7_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFSLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A0G8EMV7_BACCE --qATHKEFSQLEKKFNARLGVYVIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI00143DD343 ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTPPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=9 Tax=Bacillus TaxID=1386 RepID=A0A1H6U3I4_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. OK665 TaxID=1500305 RepID=UPI00056D89B7 ---DIEKQLAALEKRTGGRLGVYVLDTKTKVTF-AHRPDERFAMCSTFKALAAAFVLARVD -RGEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVGELCAATVTYSDNAAGNLLLASFGGP -KGLTDWLRSTGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLLEDVLSPASRD -QFSAWLVANTTGDRRLRAGLPKDWIIGEKTGTSGRGEAGDIGFMHPTEGHTILASVYIAE -GKKPTKELEPVFAEVGKLIA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8N2F7_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000E35979D --qAMHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ZS0098 TaxID=1904044 RepID=A0A421P574_9ACTN -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA -LLTDWLVRNRTGDRRIRAGAPRGWRVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE239FD ---EIDRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETESFPMCSTFKVLAAGFVLARVD -KGEENLERRVVYDKDKLVTHSPETEKHVGGEMSVGELCQAAITQSDNTAGNLLLESFGGP -KELTNWLRTLGDGSTRLDRWETDLNEAKKGDQRDTTTPDAMLDTLGNLTLGSVLSEPSQS -KLVEWMVANTTGGTRLRTGLPDTWKIGDKTGTGNNGTAADIAVAWPPGHGPILMTVYVAD -ATAEISEINAIFGEVGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A2N8Q9F8_9BURK --eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLTAGFVLMRVD -HGQETLERRVVFSKGDLERYSPATSRHTRELMSVADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGDLRELLLGERLSAPSRA -QLLAWLAANQTSGERIRAKLPKDWGVGDKTGSGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARCNAAIADVGEVVVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000872E4C8 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. TaxID=1872427 RepID=A0A2E5TE13_9GAMM ------STVQEIESRLNARVGIAVSDQETGRAW-RYHADQRFPLASTFKVLACGALLHKVD -AGDDRLDRMIDYGEADLVTYSPATGEHVDTGMTLGALCEAAITLSDNTAANLVLDAIDGP -AGLTRFLRGSGDNVTRLDRREPALNEATPGDPRDTTTPDAILETLRELLFGDTLTEPSRR -QLLQWMKGDQVADALLRAGIPDDWTIGDKTGAGGHGSRAIIAVMWPPQRGPILAAIYITE -TDATLEQRNAAIADIGRALA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=G9Q704_9BACI -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea vagans (strain C9-1) TaxID=712898 RepID=D6YR32_PANVC --qTLTSQLETLESNSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPVTRKHIGSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRHEPGLNTAIPGDERDTTTPSAMAESLKKVVLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -HDKDAATRKDVLASAAMLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. K24 TaxID=1472716 RepID=UPI0004AB0FB4 --eAIRQRLAQIEAESGGRLGVSILDTTSGLHT-GLRTDERFPMCSTFKLLTAGFVLMRVD -HGQETLERRVVFSKGDLERYSPATSRHTRELMSAADLCKAAITLSDNTAANLLLASFGGP -AALTAFARSIGDGVTRLDRNEPTLNEATPGDPRDTTTPNAMLGDLRELLLGERLSAPSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGSGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARCNAAIADVGEVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B5A4F39 ------DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDAGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVYPGDVHDTSTPKALATSLQAFALGGILSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0009C0C6A2 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora halophytica TaxID=47864 RepID=A0A1C5HVZ3_9ACTN ------AEFAALEQRYDARLGVYALDTGSGRTL-AYRADERFAYASTFKALAAGALLAATS ---DAELDRVVRYGREDLVMHSPVTEKHVADGMTLREAADAAVRYSDNTAANLVLAELGGP -AGFERALRGIGDTVTDPARTEPALNEAAPGDVRDTSTPRAMADSLQAYAIGGALSVEDQR -VLLDWLKRNTTGANLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDAAPIVLAVMSRR -DTKDARHDDALIAEATRVTLK-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A0S2DMN2_LYSEN --eALRAKLAELEKRSGGRLGVSALDTGDGRRF-DLRGDERFAMCSTFKFLLSAAVLHKVD -RGDLDLRQRIAVPKSALLPHAPFTAPIAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP -AGLTRFLRGIGDAVTRLDRNEPELNTAIPGDPRDTTSPNAMLASMRTLLLGDALGAASRK -QLTDWLIANKTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPTGRKPVFVVTYLTQ -ARGEDEQRSAILADCARALAAHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346QRV7_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIATLGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5LR19_9BACT ---DFTNRILSIEQRTGARIGVAALDTGNGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD -NGQEKLHRFVFYGANDILEYAPVTKAHLKDGMTLGALCAAAIEQSDNTAGNLLLDTIGGP -VGLTNFARSVSDETTRLDRKEPELNSAIPGDERDTTTPAAMCADMQRFLLGNVLSESSQN -QLQDWLRQNETGSLMIRASVPKTWTVGDKTGGCGNGATNDVAIIRPPGRAPILVAIYSIG -STSSADDRAAIVAEPARAVVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00136E7BD1 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDQVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A2B4BB70_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF4404A -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A423GKV5_9PSED ---ELYKKLAELEDSAKGRLGVALINTANGHEI-QYRGGERFPFCSTFKLMLAAAVLHKSM -AEPGLLEKHIAYAEADLLSYAPIAKQNLKQGMSVAQLCAAALQYSDNTAANLLIKELGGV -AAVNLFVKGLGDPAFRLDRQEPELNTAIPDDPRDTTTPAAMAASVQKVVLGGALATPQRE -QLATWLKGNTTGDASIRAGTPAGWIVGDKTGSGDYGTTNDAAVLWPQTGAPVVLAVYFTQ -HQKDAEARRDVLATATRLVMAH- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. K2I17 TaxID=2014743 RepID=A0A246PJC3_9BACI -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2B9U885_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNEIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000A80BE43 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNNVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDANYDNALIAEAAKVALD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J8LLS3_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYNNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora olivasterospora TaxID=1880 RepID=A0A562IF15_MICOL ---------GRLEARFGARLGVYAVDTGSGRTV-AYRPDERFAYASTIKALAAAAVLDETS ---SAQLDEVVRYKMSDLVPYSPVTGKHVADGMTLRALADAAVRYSDNTAGNLLLARLGGP -EGLERALRGIGDRVTEVARVEPDLNAATPGDVRDTSTARALATDLRAYALGDALSAEDRA -VLVDWLKGNATGATLIRAGVPAGWEVADKSGTGGYGTRNDIAVVWPTGGDPIVLAVLSRR -DDKDASYDDALIAQAAKVAVA-- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DE76B06 ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLHQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI00112349FB -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAVAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A243ERY1_BACUK ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELANASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 TaxID=1801944 RepID=A0A1G2W7J1_9CAUL ---AADAALADLEQRHGGRLGVVIWRPADGLRI-ARRADERFAMCSTFKTLAAAAVLARVD -RGREDLERRVVFGKDQVVTYSPVTGPRVGGDMTLAEICAAAIRFSDNTAGNLLLDSLGGP -AGLTRFARGLGDEITRLDRYETLLNEATPGDPRDTTSPDAMARNLRKLLLGPTLSSESRR -RLSQWMASNTTGDARIRRGIPTGWVVMDKTGAGENGANNDVAVILPPSGRPAIVTVYYAE -SQATGAQRNAVIADVARVAAR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Yersinia intermedia TaxID=631 RepID=Q1W757_YERIN ---SLDKQLAALEHSANGRLGIAMINTGNCTKI-LYRGARRFPFCSTFKFMLAAAVLGQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLLKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTALPNDPRDTTTPAAMAASINKLVLGDALHPAQRS -QLTAWLKGNTTGDATIRAGAPTDWIVGDKTGSGDYGTTNDIAVLWPTKGAPIVLVVYFTQ -REKNAKPRRDVLA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013D09F2D ------PRFAALETTAGARLGVFAVDTGSERTV-AYRQDERFPMASTFKGLACGALLREHP -LSTGYFDQVIHFSAAELVEYSPVTETRVESGMTVAELCHAAITVSDNTAGNQLLKLLGGP -QGFTAFLRSLGDETSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA -QLTSWLVANTTGGSRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSTK -SEQDAEPDNGLLADATRAVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0010BE7195 -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar kim TaxID=180847 RepID=A0A243AES4_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A443TI66_BACMY ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKGDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPAHKRN -ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAASYGTRNDIAIVWPPNRAPIIIAILSSR -DEKEATYDNQLIAEATEIIVNAf ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI000BE7006C ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKIVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMVERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Ensifer alkalisoli TaxID=1752398 RepID=A0A1E3V6B3_9RHIZ --dDVAKQLEELEKRTGGRLGVSVLDTRTNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEALDRRIAFGRDVLLPHSPVTGKHVGGNMTVAALCEAAITISDNAAANLLLESFGGP -AGLTSWLRSIGDEATRLDRMEPELNEAAFGDPRDTTTPAAMLETLRKLAFGSVLSESSRQ -RLVGWMVANKTGGARLRAGLPRDWRIGDKTGTSMAGAVSDIGFAWPDGRGPILVAVYTGE -AKAPLDALNPVFAEIGRIIA--- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A221BYY2_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=3 Tax=Bacillaceae TaxID=186817 RepID=A0A1Y0TYS1_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B4B7061 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A4R3SDD7_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIADAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseorubens TaxID=66897 RepID=A0A656REK9_9ACTN -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERISYGAADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA -LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRANDVAVLWPGGGSPLVLSVLTDR -PDRDASGQDELVAEATRRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora marina TaxID=307120 RepID=A0A1C4XDA7_9ACTN ------QAFRLLEEKFDARLGVYAIDTGTGRTV-AYRPDERFAYASTYKALAAAEILDETT ---DTELDRVVRYSADDLVTYSPITEQHVATGMTLRAITDAAVRYSDNTAANLMLRHLGGP -QRFERELRGIGDKVTDPERYETELNEARPGDRRDTSTPRALAGSLRAYTVGDALEPPDRA -TLNDWLRRNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDADYDDALIAEATRVVTAGw ->[subseq from] Beta-lactamase n=1 Tax=Herbihabitans rhizosphaerae TaxID=1872711 RepID=A0A4Q7KMF8_9PSEU ---DLGQRFAALEQQYGARLGVYAINTRTGVTV-THRADERFPMCSTFKTLAAAAILRDRD -QHGEFLAKVIPYARADLVANSPVTEKHVGAGMRVDQLCAAAIQYSDNTAANLMLREIGGP -AGVTAFCRSIGDPATRLDRWETALNSALPGDPRDTTTPAAIGRDYDQLVLGRALSREDAA -LLTGWLCGNTTSSKRFRAGLPVGWRLGDKTGGGDYGTNNDVGVTWTTRGTPLVLVALSTR -HTQDAAPQDALLADTARLLA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009ADABA7 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. NH11B TaxID=1866314 RepID=UPI0009F9BB65 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVINYTKDDLVEYSPVTEKHVDTGMTLGEIVEATVRSSDNTAGNILLNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKEDTYDNQLIAEAAKVVIN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E4E49E ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A160H0Y6_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B4DB372 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D3E1920 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia silvatlantica TaxID=321895 RepID=UPI000D5CC207 ---SLEKPLAAIEAQAGGRLGVAMLDTANGHVR-GWRMQERFPMCSTFKVLLASAVLTRKD -HGKEDLARKIVYSPAQVVSYSPVSGPRAGSEMTVAELCEAALTRSDNTAANLLLESIGGP -AAITAFARSIGDPVTRLDRNETTLNDAIPGDPRDTTTPAAMVANLRELLLRERLASVSRE -QLIAWLVANKTGDARLRAGLPKDWRVGDKTGTGDHGTANDVAIIWPTGRAPILVTAYLTG -ATASPSQRDAAIAQVGV------ ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S7BJL4_9XANT ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVTIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -PGLTTFLRGIGDAHTRSDRREPEMNRYAEGDARDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGETCLRAGLPRGWKIGDKTGSNGSDTRNDIAIIWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679H866_9BACI -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar pakistani str. T13001 TaxID=527027 RepID=C3E3Q8_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYNNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=3 Tax=Xanthomonas TaxID=338 RepID=A0A1S1XKL8_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2B3B8X7_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=A0A1B1C4W1_RHILE ---NIDRRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENIDRRVSYGKDKLVDYSPISEKHADTDMTLAALCEAAVTVSDNTAGNLLLESFGGP -AGLTNWLRSIGDGTTRLDRTEPTLNEGRRGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGNIAVIWPPDRGPIVAAVYISE -TTVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI0004A21FA8 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011445C1E ----TYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKAIAAGVLLQKNS ---TEKLNEVITYTKEDLVDYSPVTEKHVGTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTLSDRFETELNEAIPGDNRDTSTAKAIATNLKNFTIGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas graminis TaxID=158627 RepID=A0A1C2E2J1_9PSED ---AIAQQLAELERRHGGRLGVAILDTSSQRLI-SHRGDERFPLCSTFKCLAAACVLARVD -QKHEDLSRRIVYSAEQLVAYSPTTELHAGGQLSVGSLCEAAMTLSDNTAANLLLDSVGGP -EGLTAWLRSMGDTQTRLDRREPELNENRPDDLRDTTTPVAMLQTLNTLVLGEKLTPASRD -QLTAWLVNNQTGDKKLRAGVPVSWRVGDKTGSGANNASNDVAVIWPGERGPMLVTAYYTC -SKASGDQINALMTDIGRLAA--- ->[subseq from] Beta-lactamase n=2 Tax=Paludibacterium purpuratum TaxID=1144873 RepID=A0A4R7B2X1_9NEIS --qAIRQHLSQLERSTNGRLGVALIDTADNSRV-GYRADERFPLCSTSKVMAAAALLKLSE -SQRGLMQRDIAIERSDLVNYNPVTEKYVGGRMTLAALSAAAVQYSDNVAMNKLIEQLGGP -QAVTRYSRTLGDRAFRLDRKEPGLNSAIPGDERDTTTPAAMAESLRKLTLGDALQAPQRE -QLVNWMKGSTTGAASIRAGLPASWAVGDKTGSGAYGTTNDIAVIWPTGRAPLILVTYFTQ -KAPKALARRDVLASAAHIVIQ-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B430894 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAXXX-LQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHQIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEAAYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. OLGA172 TaxID=1804984 RepID=A0A160FUW9_9BURK ---AIRQRLAQIEVESGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKLLAAGFVLTRVD -HGQEDLERRIVFSKSDLVPYSPATSQHTRERMSVADLCKAAMTLSDNTAANLLLASFGGP -SALTAFARSIGDGITRLDRNEPTLNEATPGDSRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANQTGGERIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPILVTVYLTE -TSGDAARCNAASASVGALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Reyranella sp. CPCC 100927 TaxID=2599616 RepID=A0A5C5SUV3_9PROT -------ACRRIEAKVGGRLGVAVMDTTSGTRA-SHRGGERFPILSTFKALACGAVLKRVD -DGKETLGRRIQYSAGDLVPHSPTTKAHVADGMTLADLCTATMTLSDNTAGNLILQALEGP -EGLTRFVRGLDDKITRLDRWEVALNEAATGDPRDTTTPDSMAENLRKLVLGDTLSASSRN -QLTAWLVANKTGDARLRAGLPKTWRVGDRTGTGDNGATNDVAVAWPPGRGPIIICVYLTE -TRAALDDRNAAIAAIGWTVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter fonticola TaxID=2603215 RepID=UPI0011E88C9C ----FDEAMAEIESQNGGRLGVAVLDTASGERL-TYRANERFAMTSTFKWVLVAAVLSRVD -AGEDALDRQIQYDESDILSYAPIAKQHLPAGMTVAELSDAAIRYSDNTAANLLLETLGGP -AGLTAYIRTLGDDMTRLDRNEPGLNTNRPGDKRDTTTPAAMVGLMRLALVGDALSAASRQ -QLQDWLIRNTTGDTKLRAGLDPDWTVGDKTGAGDRGASNDVAIVWPKKGAPILIAVYYSG -TMLPNEALNAVHAEVGRVIAGVf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B52F65 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0012B9C763 ------EQIKISEGQLAGRVGYVEMDLARGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5M8SFT9_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SGFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0G4D0X4_BACTO -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK11 TaxID=1628212 RepID=A0A0J6NMN1_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -QQPGLLDKRIRYSKTALPNWSPITTKQQANGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDASFRLDRLEPELNSAIPGDPRDTSTPKAVAESMQKLALGKALPEAQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSNEVIAAAARAALEAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011A09D4B --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IATLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobacter sp. OV335 TaxID=1500264 RepID=A0A1M7ISV9_9BURK ----ADARWAAIEADVGGRLGAAVLDTGSGRVD-GHRLDERFPMCSTFKWLAASLVLQRVD -AGLERLDRRIVVRREVLIANSPVSEQHVGGDMSIAELCEATVLVSDNAAANLLLASFGGP -PAITRHARSLGDTKTRLDRTEPALNEARPGDPRDTTTPRSMATALRSALLGTALSDASRA -RLVAWMEAVRTGTDRLRAGLPPDWRVADKTGTGARGSTNDVAVAWPPNRAPLVITAYLTD -SKADAKRRNAALAAVAREAA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RBZ2_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQMGDNVPRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI24_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDXAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. THAF35 TaxID=2587854 RepID=UPI00126887C3 ----LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARA -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI000BF933F0 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A0J6ZMN3_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus TaxID=1396 RepID=R8S2C7_BACCE -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8GCP6_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVQKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPQNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Duganella sp. Leaf61 TaxID=1736227 RepID=A0A0Q4P523_9BURK -----AAQLARLEADTKGRLGVAAINTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP ----SLLDKRIRYTAADLVSHSPVTEQNLADGMTVGELCAATIQYSDNAAANLLMKQIKGP -AGVTAYARSIGDKAFRLDRWETELNTAIPGDPRDTTTPLAMMKSLQSFTLGPALTVDKRN -LMTEWLIGNTTGDTRIRAGVPYDWQVGDKTGTGSYGSTIDIGVVWPAGKAPVVMALYFTQ -PGKDDKANSEILASAARVVVEAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI00111D8366 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A1S9YVE7_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001444039B -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2T5NY59_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPMCSSFKGFLAAGVLAQSQ -DKPSLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALDKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=J3ZVN2_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=17 Tax=Bacillus TaxID=1386 RepID=A0A0Q0V245_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0002794A92 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. SNU WT3 TaxID=2590869 RepID=A0A4Y6RJB9_9BURK ---AAHTQLAALEQAAGGRLGVAAWRQGSELRV-TYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAAALQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAHGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3109E -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0013314A7F -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ZZV12-4809 TaxID=2575830 RepID=UPI00135A5632 ----TNQKFKQLEKKFDARLGVYAYDTGTKKKI-AYRSNERFAYASTFKPLAAAILLERKS ---LEEMDEIITYTSDDLVTYSPVTEKHVDTGMTLRELCEAAIRYSDNTAGNIILEELGGP -EGFKAALKEMGDTVTRPERFETDLNEAKPGDIQDTSTPKALAASLQKVLIGDFLTEEKRN -ILTDWMRGNATGDPLIRAGVPSGWEVADKSGAAGYGTRNDIAIIWPPDREPIIMTILSSR -KTKDAEFDNALIAEAAEMTIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B4BA30_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus AH1272 TaxID=526993 RepID=C2Z896_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000E23DE59 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNDIIRYTKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSFGTRNDIGIVWPPDRAPIVLAILSKR -FTKDANYDNALIAEAAKVAFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000992149D -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALVTSLKAYALGDILSIEKRN -FLIDLMKKNTTGDNLIRSGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. CP4 TaxID=1674922 RepID=UPI0007852749 ----LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSTTARA -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. CF099 TaxID=1882791 RepID=A0A658UKH1_9BURK ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKEQLGRTIAYSKEVVVANSPVSGPRAGDDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEAMEADPRDTTTPAAMLADMRALLLGGHLSAASRE -QLTAWLAGNKTGDARLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. N35-10-4 TaxID=1866315 RepID=UPI0009F8121B --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGS -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5P9YC78_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFMLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI00072A49A8 --nDIEQQLTALEKRTGGRLGVYVLDTKTKASF-AHRPDERFAMCSTFKALAAAFALARAD -KGEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVRELCDATVRYSDNAAGNLLLASFGGP -KGLTDWLRSIGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLIGDVLSPASRD -QFSAWLVANTTGDRRLRAGLPKDWTIGEKTGTSGRGEAGDIGFMRPAEGHTILASVYIAE -GTKPTKELEPVFAEVGKLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora azurea NA-128 TaxID=882081 RepID=H8G598_9PSEU ----VQGELRALEARHAARLGVYGINTRSGAVV-SYRAHERFPMCSTFKTLAAAAVLRDLD -RDGEVLDSWVHYTEDDLVVGSPVTERHVGTGMRVADLCAAAVSESDNTAANLLLDRIGGP -RGVTRFCRSLGDRLTRLDRYEPDLNSALPGDLRDTTTPAAIAEDYRRLVVGTALDRGDRA -RLTTWLTESVTSDTRFRAGLPSHWRVADKTGSGSYGTANDVGVAWTDDGTPLVLAVLSTK -HTPDAEWDDALVARTARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3FB10 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. ORS 285 TaxID=115808 RepID=A0A1Y6KF39_9BRAD ---DLQATIAGIETDSGGRLGVALLDTANAALS-GHRLDERFPMCSTFKALLAAAILTKVD -AGAEQLSRRLPITQADILSYAPVTKAYVGTSLSVGELCEAAVTLSDNTAANLLLATLGGP -AGLTRAVRGFGDAITRLDRIEPELNESVPGDPRDTTTPAAMAQTLAKLTTGNTLSAASRD -VLNGWLIGCKTGAARLRAGLPASWRVGDKTGTGDNGSSNDVAVIWPAGRAPVIVTSYLTE -TKAGDDKRNAVHAAVGRAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9BHS8_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. S66 TaxID=1842608 RepID=A0A3B0A754_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001155B6C9 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011ED41C5 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter hydrocarbonoclasticus TaxID=2743 RepID=A0A455W4T9_MARHY -hnALIKTVEKVADDLEALVGFAAYDLESDQRW-EYHADQRFAMSSTFKTLACAALLHRVD -AGQENLARKVNVSESDLVTYSPITEKHAGGEMTLSDLCEATLTTSDNTAANLVLRALGGP -EAVTSFARHLGDDVTRLDRWETELNEALPSDNRDTTTPNAMVRNLQALLLGNALSEPSRE -QLRDWLEGNQVAGGLFRAAVPEGWIVADRTGAGGFGSRSITAVIWPPERQPIVVALYLTQ -TDASFGERNAAIAEIGEAIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004C200EF -------DFRQLEKRFGARLGVYAIDTGTGRTV-RYRADERFAYASTFKALAAAEILDETT ---DSELDRVVRYSADDLVTYSPITEQHVTEGMTLRAIADAAVRYSDNTAGNLLLRQLGGP -QKFEKELREVGDKVTDPARYETELNEARPGDRRDTSTAAALAEDLRAYAVGDALEPADRD -VLNGWLRGNTTGGDLIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DQKDADYDDALIAQAAEVVI--- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus TaxID=1396 RepID=A0A5S4HTN7_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HF61_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIRYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8R8_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQAAMDERNRQIAE--------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HID4_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -TGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ab134 TaxID=1898042 RepID=UPI00117A42CF ---ELLDTVNRLEQEVGGRIGVVLQHTGSDWAI-ETRADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEAKPGDARDTTSPRAVVQTLDRLLFEEVLQPSSRA -QLQQWMVDDKVADALIRKHLPAGWRIADKSGGGYNGSRGIIAVIWSETGEAYLTAVYMTG -SNADFKKRNAVIAEIGKAIIE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A5R8NCK8_9NOCA ------PRFAALETTAGARLGVFAVNTGSERTV-AHRADERFPMASTFKGLACGALLREHP -LSTGYFDQVIHYSAEELVDYSPVTETRVESGMTVAELCHAAITASDNTAGNQLLKLLGGP -QGFTAFLRSLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA -QLTAWLVANTTGDTRIRAGLPEDWTVGDKTGSPAYGSALDVAVTWPSGRAPIVIAVLSTK -SEQDAEPDNRLVADATRTVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000E27098A -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALTTDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=S3JEY9_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA73C74 -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALTTDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000B4DEBA8 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPEDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=13 Tax=Bacillus TaxID=1386 RepID=A0A5F0X974_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A249XB53_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD8C508 --eDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -RGDETLDRRITYGREKLVTYSPETEKHAGGEMTLADICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN -RLVDWMVANTTGAARLRAGLPRDWRIGDKTGTGDNGAAGDIAIIWPPGRGPIVAAVYMAE -TTVKMDEFNPVFAEIGRMIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J8K162_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=7 Tax=Bacillus TaxID=1386 RepID=A0A2A8E5G7_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1S7F5Y6_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XRK6_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4R1EGR5_BACCE -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIAEATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC 00631 TaxID=2203201 RepID=A0A428W3K6_9ACTN ---EASRRLRALESEHGARLGVFARNLDTGETV-VRRADERFPMCSLFKPVAAAAILRDHD -RRGEFLARRIRYGTTDLVEHSPITGKHVAQGMTVGELCDAAIRYSDNTAANLLLRELGGP -RAVTRFCRSVGDRTTRLDRWETELNSAEPWRVEDTTSPRAIARTYTRLIVGDTLSSADRE -RLTGWMLANTTSGERFRAGLPADWDLADKTGGGAYGTNNNAGVAWTPDRAPIVLAVLTTK -PAPDAAPDNELIAETAELLA--- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Ensifer sp. M14 TaxID=2203782 RepID=A0A395LE97_9RHIZ ---DVDARLAELEKRTGGRLGVSVLDMDTNISF-GCREDERFAMCSSFKTLAAGFILARAD -QGAEKLDRRLVVAQKDIIAHSPITEKHVGGEMTIADLCASTMTTSDNAAANLLLESFGGP -QALTAWLRTIGDDTTRLDRNEPTLNEAKIGDPRDTTTPAAMLETLGNLAFGPALTEPSRK -LLIEWMVANTTGDQRIRAGLPKGWKVGDKTGTNSTGSASDIAIVWPEGRGPLLIAVYIAE -ATAPLAELNTVFADVGRMAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora pattaloongensis TaxID=405436 RepID=A0A1H3RXP3_9ACTN ---SAQRTFAQLEAGFDARLGVYAIDTGSGRTV-QHRADERFAYASTFKALLAAVILDVTS ---PAGLDRVIRYTEADLVTHSPITEQHVGEGMTLRALADAAVRYSDNTAANLLLRYLGGP -HRFEKALRAIGDRTTEADRYETALNEAVPGDKRDTSTPRALAADLRAYAVGRGLDRDDRD -ILNAWLRGNTTGDELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DQKDAGYDNALIAEATRLVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS094611 TaxID=2033516 RepID=A0A2A7DZH1_9BACI ---TVNHPFSKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHLGDTHDTSTPKALATSLQAFGLGDVLSTDKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDANYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase 1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=BLA1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTEWMKGNATGDKLIRAGVPTDWVDADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2VDV3_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A0J7HAJ3_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2BY31_STRVZ ----ALRRLRALEESYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKALLAAAVLRRAR -EEPGLLDVLIRYGRDDLVTHSPRTEMHLETGMTVRELCDATVTYSDNAAANLLMRRIGGP -VGVTEFARSLGDTRTRLDRWETDLNSNIPGDRRDTTTPAAMTANLRKLVLGKALHPLDRG -QLIRWLVENTTGDKRIRAGVPKDWRVGDKTGSPAYGGVNDVAVAWPPKQAPLVVSVYTTR -LDPDTPGEDRIAEDITRIVVD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8GC16_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. SSI4214 TaxID=2575739 RepID=UPI00143B62FC ---SLSLRINALEKRGGGRLGVAVLDTQDGRRF-AARGDERFLMCSTFKMLLAGLVLRRVD -QKRERLDRRVQYGPEVLVDYSPETKKHVGPGMTIANLCQAVITLSDNTAANLLLDAVDGP -VSVTRFARALGDPVTRLDRIEPALNTARPGDLRDTTSPKAMLETLRTLTVGDALTAESRA -RLVGWLVANQTGDARLRAGLPKTWKIGDKTGSDGRHTANDIAVIWPPGRAPLLITTYLTG -AKLDDDGRDAVLADVARAVVT-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2XBX2_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. KC721 TaxID=2530380 RepID=A0A4R4KQU3_9ACTN ----ASADFASLEQRFDATLGVYAIDTGTGRTL-AHRADERFAYASTVKALAAGALLDVTS ---DAELDRVVRYRRADLVTYSPITEQHVDTGMTLRAVADAAVRHSDNTAANLIFAELGGP -DGFERELREIGDTVTEPARIETALNEAAPGDVRDTSTPRAMATSLRAYALGDALSAADRA -VLVDWLRRNTTGAKLIRAGVPADWQVGDKTGSGGYGTRNDIAVLWPPRGAPIVLAVLSRR -DTKDAAYDDALIAEAAKLAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD92F26 --nDINRQLASLEKRTGGRLGVSVLDTKSNVSF-GHRQDERFAMCSTVKALAAAFVLARVD -KGQETLGRRIDVSKADLHAHSPVAEKHVGDGMTVGELCDAAVTYSDNAAANLILASFGGP -AGLTAWLRSIGDETTRLDRTEPALNEAKPGDPRDTTTPAAMMRTLGKLLLEDVLSPSSRD -QFAAWLVANRTGDRRLRAGLPTNWTIGEKTGTSGHGEAGDVGFMRPPKSQTILASVYIAE -APKPVKELEPIFAEVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000815F2E5 -----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI00064F4650 ---DLDETFATIESEYDARVGVYAIDTGSDQTI-DYRSEERFAFASTYKALAAALVLKQNT ---MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPIALATSLQGFAVGDLLTDDKRE -LLLDWMQGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPNREPIILVIMTRH -DTEDAQYDDALIAEVAEVTLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=UPI00055E55F4 ----WSAQLRVLEKNSGGRLGVGMLDTGSGQHF-DWRGRERFPMCSTFKFLLAAAVLREVE -RGKFDLEKKIPIAKSDLIAYSPVTEPLAGSSASVAQLCEATMTLSDNTAANLLLPLVGGP -AGLTAFLRGIGDPTTRLDRKEPELNSAIPGDPRDTTSPLAMVATMRKLLLQDGLKPASRQ -QLTSWLVANRTGDKRLRAGVPKGSRVGDKTGTADT-TSNDLAIIWLPERAPILLTCYLTG -STLDGPGRDAIHAAVARLVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AB6F53 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHITKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio denitrificans TaxID=258256 RepID=UPI000FFBEC5C ---ELLDTVNRLEQEVGGRIGVVLQHTGSDWAI-EARADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEANPGDARDTTSPRAVVQTLDRLLFEEVLQLASRA -QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLTAVYMTG -SDANFKKRNAVIAEIGKAIIE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. N113 TaxID=1703960 RepID=A0A192LTR1_9RHIZ ---NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRASEAFPMCSTFKALAAGFVLARVD -KGQESLERRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSVLAEPSSE -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C3Z4M1_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4L015_BACCE -----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFA3FB9 -----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock4-2 TaxID=526987 RepID=C2WPJ9_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGKTHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI000DE92309 ----TYKEFFQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFSFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI00080C63B4 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKKP ---IEKLNDVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKTFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDANYDNALIAEAAKVALD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243DAQ4_BACTU --qATHKEFSQIEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. WMMA1996 TaxID=2039878 RepID=UPI000BF6DF10 -----DRAFRHLEETFDARLGVYAIDTGTGRTV-GYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITEKHVADGMTLRALADAAVRYSDNTAGNLLLRRLGGP -QRFEKELRGVGDKVTAPARYETALNEARPGDRRDTSTARALAQDLRAYAVGDALDPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVVWPPDRAPIVLAVLSSR -DQKDADYDNALIARAAEVAI--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1E8BNH7_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI001117E61B -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb56 TaxID=1827287 RepID=A0A2S9I3C6_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0013D2B4F1 -----NQKFVQFEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI0012E7B5DE ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALISEAAKAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI0010391485 -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPEDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A5P0YA13_9BACI ----TAKKFMQLEKKFDARLGIYAIDTHTNRTV-TYRPDERFAYTSTFKALASGLILQQKS ---IDKLNEVITYTEDDLVTYSPITEQHVDTGMTLREICDAAIRYSDNTAGNLLLKELGGP -NGFEKALREMGDNVTKADRYETDLNSAIPGDIRDTSTARALATNLKSFTVDDELPNDKRE -ILTDWLQRNTTGDELIRAAVPKGWEVGDKTGAGDYGTRNDIAIVWPPNRDPIIIAILSSR -DTQNATYENELIAKAAKVALNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD81D17 --eDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -RGDETLDRRITYGREKLVTYSPETEKHAGGEMTLADICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN -RLVDWMVANTTGAARLRAGLPRDWRIGDKTGTGDNGAASDIAIIWPPGRGPIVAAVYMAE -TTVKMDEFNPVFAEIGRMIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. Root133 TaxID=1736455 RepID=UPI0006F5DC2E ---DATQALAGLERRAGGRLGVAAWRRGGADVI-AWRGDERFPFCSTAKVMVVGTVLTLAA -RTPALLDERVRYKKADLVSWSPVTEQHVDDGMTIADLCAAALQVSDNSACNLLLDRIGGP -AAVTAFARRIGDTAFRLDRRETELNAAIPGDPRDTTTPRAMARSLEALLLEEALAPDARR -RLLDWMLANTTGKERIQAGFPADCRVADKTGTGAHGTTNDVGLVFPPQGQPVIVAVYYTG -SKSDS----KVVADAAAIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium favelukesii TaxID=348824 RepID=W6R6G1_9RHIZ --dEINRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETERFPLSSTFKVLAAGLVLARVD -KGQETLERRVVYDQAKLVTYSPETEKHVGGEMSLSELCAAAITLSDNTAGNLLLESFGGP -PELTKWLRTLGDRSTRLDRWETALNEAKDGDPQDTTTPDAMVDTLGNLALGSALSEPSRD -KLTEWMVANTTGGARLRAGLPGAWRIGDKTGTGNNGSAADIAIVWPPGHGAILVAAYVTQ -AKAPLSEINPVFAEVGRIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00111A540E -----NQKFVQLEKKFDARLGLYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8QDG0_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALVTSLKAYALGDILSIEKRN -FLIDLMKKNTTGDNLIRSGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=6 Tax=Xanthomonas TaxID=338 RepID=A0A0A3XJ82_XANCH ----LRAQWAQIERGTGGRLGVCLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTRWMIDNRTGDDCLRAGLAADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces marokkonensis TaxID=324855 RepID=UPI0011F1FB0C --------LAELEREYGARLGVYAVATGTGATV-IHRADERFAFCSVFKTLAAAAVLDRGP ---RARLDERVTYTRADLAAHSPVTERHADTGMTLRRLCDAAVRHSDNTAANLLLREVGGP -RAVTAYLRGLGDSVSRLDHYEPELNRNPPGDPRDTTTPRAVAADYRALVLGDALPAAERT -TLTDWLVRSTTGGRRIRAGVPRGWTVGDKTGTGSWGRANDVAVLWPGRGAPLVMAVMTDR -PGRDAAPSDALIAEAARRVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG6O-2 TaxID=1053193 RepID=J9BEQ4_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0DFD7 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRITYGKDKLVTYSPETEKQAGGDMTMAEICKAAITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLIDWMIANTTGGARLRAGLPGDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium freirei PRF 81 TaxID=363754 RepID=N6U0H5_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GLRQEERFPLCSTYKALAAGFVLARVD -QGVEKLDRRVTYGKEVVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESVGGP -AALTSWLRVTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLINWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVGKIIVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0005C87D2A ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1T3VJX5_LYSEN --eALRAKLAELEKRSGGRLGVSALDTGDGRRF-DLRGDERFAMCSTFKFLLSAAVLHKVD -RGDLDLRQRIAVPKSALLPHAPFTAPIAEAGASVAQLCEATMTLSDNPAANLLLPLVGNP -AGLTRFLRGIGDAVTRLDRNEPELNTAIPGDPRDTTSPNAMLASMRTLLLGDALGAASRK -QLTDWLIANKTGDKRLRAGLPKDWRIGDKTGSGN-GTTNDIAIVWPTGRKPVFVVTYLTQ -ARGEDEQRSAILADCARALAERw ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BE24D5 -----TPQFAELETTYDARLGVFAVDTGSGRSV-AHREGERFPMASTFKGLACGALLRDHP -LSTGYFDQVIHFPASDLVEYSPVTETRVETGMTVAELCDAAITVSDNTAGNQLLKLLGGP -EGFTAFLRSIGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRTLVVGDTLAEPERA -QLTSWLVANTTGDTRIRAGLPGDWKVADKTGSPAYGSALDVAVTWPPGRAPIVIAVMSTK -SEQDAEPDNALLADATRAAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012F5144E -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKV----- ->[subseq from] Beta-lactamase n=1 Tax=Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT) TaxID=572265 RepID=C4K574_HAMD5 -hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD -AGLEQLDRRIKYRQSDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP -KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILSVKSRQ -QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE -TQATMDERNKQIAEIGASLIKNw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock3-28 TaxID=526983 RepID=C2UW73_BACCE -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQQKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPREWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NMN5_9ACTN -----DHEFRRLEERFDARLGVYAIDTGTGKTV-QYRAEERFAYASTFKALAAAEILDETT ---DAELDRVVRYSADDLVNYSPITEQHVAEGMTMRAIADAAVRYSDNTTANLMLRHLGGP -QKFEKELRKIGDKVTDPARYETELNEGRPGDRRDTSTPRAMAGSLRAYTVGDALEPTDRD -TLNGWLRGNTTGGALIRAGVPDGWVVGDKTGSGGYGTRNDIAVIWPPNRAPIILAVLSSR -DEKDADYDDALIAEATKVVMANw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2WPN3_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-53 n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A6A9RRF8_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Albidiferax sp. OV413 TaxID=1855285 RepID=A0A1H0SBA4_9BURK ---SASQQLQALETAATGRLGVAAFG-AGGASL-LHRAEERFPACSTFKLLLASAILARSA -QDPGLLQQRIRYTAADLVSYSPITEKHVADGQTVAELCAAALQYSDNSASNLLMRTLGGP -PAVTAYAHAIGDTSFRLDRWETDLNSAIPGDTHDTCTPAGMARSLQTLLLGDALALPQRT -QLKDWMLGNTTGATRIRAGVPADWRVADKTGAGSYGTTNDIGVVWSPAGTPVVLAVYFTQ -PDKGAPMRNDVVAATTRIAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. D3 TaxID=1638164 RepID=UPI000786019A ---DLDALWAEIENRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD -AGQENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALSQSDNTAGNVLIDLLGGP -EGVTRTARGFGDESFRLDRRETALNEAKPGDPRDTTSPAAMTKTLHALLFGEALKPDSRR -QLADWMVANRTGDAKLRAGLPKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILVSLYLTE -TKASFDARNAAFAEVGRAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCBBF3 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGTEKLDRRVIYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPILVTTFVAE -ATASAKDIEAVFAEVSKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G5-5 TaxID=2485160 RepID=A0A3N4UVE4_9ACTN ------HQLHRLEHQHGARLGVFAHNVRTRKTV-AHRADERFPICSVFKTLTAGAVLRDLD -HDGEVLARRIHYTRADLVDGAPITDEHLANGMTVEELCDAAVRYSDNSAANLLLRLLGGP -TAITRFARSLGDRVTRLDRWEPELNSAEPGRITDTTSPRAIGRDYGRLVLGEALNRRDRD -LLTHWLLNNTTGANRIRRGLPDTWTVGDKTGSGSYGTTNDVGIAWTPEGAPIVLAVLSTT -PDQDRPWDDALIAEAAALVAD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F942_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSHVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLXAGLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A1W6WPL7_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia aggregata TaxID=187304 RepID=UPI00094AE6AD ----LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -EGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGNALSSTARA -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacteriaceae bacterium A-F18 TaxID=2045202 RepID=UPI0013EC2226 ------ETVKKAEDQLNARVGYAELSLANGQMLgSYRPQERFPMTSTFKVLLCGAVLSRVD -AGQEQLARRIQYRKQDLVAYSPVTEKHLTDGMTVAELCSAAITMSDNTAGNLLLSAIGGP -SALTAFLRKAGDRVTRLDRWETALNEALLGDERDTTTPEAMAQMLRQLLNGKILTPASQQ -QLMAWMEADKVGGPLIRSVMPAGWFIADKTGAGERGSRGIVAALGPDGKPARIVVIYITE -TQATMDDRNKKIADIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus haynesii TaxID=1925021 RepID=A0A1R1RJQ5_9BACI --tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-TYRPDERFAFASTIKVLTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKLGDEVTNPERYEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWDVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B0SGY8_BACTU ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. glycines str. 8ra TaxID=1401257 RepID=A0A1D9EGD0_XANCG ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A3A5HYD6_BACIU -----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEEMGDDITNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPIEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3879 TaxID=2029406 RepID=UPI000BB07203 ----ATKAVEALESRNGGRLGVMILDVGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD -DGKAKLDDRIVYAASDVEPYSPITKDHVGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP -QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRALLGDARRILLGDALSPASRK -RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG -STAPRASREAVHRDMARIIVETf ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=A0A1I1ZDK8_9BURK -----RSGMQALEATLGARLGVAVLDTATGRAW-GWREDERFPMASTFKMALAGWMLALVD -QGRESLAQRVHFEREALVPYSPATEKHAGPGMTVGELCEAAVTLSDNTAANLLLARHGGP -AGYTAFLRSVGDEVTRLDRTEPALNEALPGDPRDTTTPAAMGRTLQRLALGDALSAASRA -QLMAWLVGNKTGDRRLRAGVP-GWRVGDKTGTGALGSSNDIGVLWPPGGAPLVVACYMTG -GAAAPAVRDAAIAQVARQAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A657V0B1_9BACI ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2B9WY18_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8L1P9_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKHDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Trinickia soli TaxID=380675 RepID=A0A2N7WGH8_9BURK --kAIEAELASIERSVDGRLGVALLDMETGMRA-GHRVGERFPICSTFKLMLAANVLARVD -RGEENLERRIVFGQDRIDQYAPVTRERTGAPMTIAELCDAIVTMSDNTAANLLLDTVGGS -AGFTAFMRRLGDTVTRLDRNEPSLNEAIPGDPRDTTTPIAMLNDLREVLLGDALTAASRA -RLLAWGVGNRTGDTRLRAGVPGNWRVADKTGTGERGTTNDVGLLWPQERQPIVVTVYLTQ -SPAPVRAREAALADVARAIVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI0011C905C5 --qTLTSQLETLESKSGGRLGLAVIDTADGSKY-AWRGNERFPLCSTSKVMAVAAILKKNE -RDPHLLDKKIHISKSDMVNYNPVTRKHIDSYMSVAELSAAALQYSDNAAMNKLLSYLGGP -QQATHFARTIGDKDFRLDRNEPGLNTAIPGDDRDTTTPSAMAESLKKVVLGTALKEEQRA -KLSDWMKGNTTGSDSIKAGLPDDWIVADKTGSGDYGSTNDIAVIWPKNHAPVILTTYFTQ -RDKDAATRKDVLASAAMLVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MB366 TaxID=1663555 RepID=A0A1Q9KJ80_9BACI -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCEBBD ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEYFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVSKIIVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. kyushuensis TaxID=44161 RepID=A0A243F4V0_BACTY -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. 61 TaxID=2035209 RepID=UPI000C710F73 ---AAHTQLAALEQAAGGRLGVAAWRQGSELRI-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio denitrificans TaxID=258256 RepID=A0A1I7BJ51_9RHOB ---ELLDTVNRLEQEVGGRIGVVLQHTGSDWAI-EARADERFPMASTFKALLCGAVLARVD -RGEERLGEVVAYSKAELVSYSPVTKKHVAEGMRVGELCEATVTMSDNTAANLLLKRVDGP -KGLTRFLRGLGDRVTRLDRREPEMNEANPGDARDTTSPRAVVQTLDRLLFEEVLQLASRA -QLQQWMVDDKVADALIRKHLPSDWRIADKSGAGHNGSRGIIAAIWPETGEPYLTAVYMTG -SDANFKKRNAVIAEIGKAIIE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. S-62 TaxID=2653123 RepID=A0A5J4M314_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEYFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVSKIIVD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium tumorigenes TaxID=2041385 RepID=A0A2W4BE57_9RHIZ ---DAGAQLAALEKRTGGRLGVAVLDTETNISL-GNRETERFPMFSTWKALAAGFVLARVD -QGKEKLDRRVSFGKEALVAYSPVAEKHAGTDMTIAELCEAAVTVSDNTAANLLLDSFGGP -AALTDWLRTTGDTETRLDRREPELNEAKKDDPRDTTTPDAMLDTLGLLTLGNTLSDASST -MLTGWLVAATTGKDRLRAGLPAEWKVGDKTGTGAQGMAADIAIVWPPERGPILVAAYITD -ATAPAAEINAVFAEIGKMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-29814 TaxID=1729688 RepID=UPI000834BEAE ---QLHREFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS ---IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVAEAAVRYSDNTAGNLLLKKLGGP -EGFEKALRQIGDNITQVDRYETDLNSAIPGDNRDTSTPKALATSLKAFAVSDLLPTEKRA -ILTDWMRGNATGDALIRAGAPAGWVVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNTLIAEAAKVALN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B0LQI5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDDRN-------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-1 TaxID=1053201 RepID=J9CI51_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6RUS8_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKCN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HNS054 TaxID=1662446 RepID=UPI000653A85B -------NLAALEREYGARLGVFAVDTGTGTTV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRHSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA -LLTDWLVRNTTGDRRIRAGAPRGWKVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B4ZZH9_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-9 TaxID=1053204 RepID=R8D0R0_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGQIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia dipogonis TaxID=1211383 RepID=A0A4Y8MQL2_9BURK ---AIRRRLAEIEAASGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD -RGEENLQRRVVFSQSDVVSNSPATSKHTRELMSVAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARGLGDGVTRLDRIEPTLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGDAARSNAAIADVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia mimosarum TaxID=312026 RepID=UPI00041523D8 ---AFEKQLAAIEAQVGGRLGVAMLDTASAHVR-GRRMHERFPMCSTFKLLLASAVLARKD -HGEEDLARRVVYSPAQVVSYSPVSGSRAGGEMTVAELCEAALTRSDNTAANLLLESVGGP -SAITAFARGLGDPLTRLDRNETSLNEAIPGDPRDTTTPAAMVANLHELLLGERLSAASRE -QLIAWLVANETGDARLRAGLPKEWRVGDKTGTGDRGTANDIAIVWPTGRAPILVATYLTG -ATASSAQCDAAIAKVGACLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 5B6 TaxID=1127743 RepID=I2HPT2_9BACI -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDEMIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000E4FC149 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase CRP-1 n=1 Tax=Chromobacterium piscinae TaxID=686831 RepID=UPI0005833D78 ----ADQKIARLERVFGGQIGVYALDTGSGAAV-SYRADERFPLCSSFKGFLAASALAHSQ -SKPGFLDQILHYGKEELIAWSPISEKHQSSGMTVAGLCAATVQYSDNAAANVLMKQLDGP -AGLTAFMRAIGDSTFRLDRWEPELNTAIPGDARDTSTPRAVAESLQKLTLGTALAAHQRQ -QLVDWLKGNTTGNQRIRAAVPAGWLVGDKTGTCGYGTANDYAVIWPTGRAPIVMAVYTRA -SKKDIKHSDAVIADAAKAALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Cyanobium sp. Copco_Reservoir_LC18 TaxID=1328305 RepID=UPI00135C96EF ---AAEAALAALEARSGGRLGVFAIDTASGARI-GHRAGERFPLCSTFKAILAGAVLHRSQ -RQPGFLEQRIRFGRQDLVSHSPVAEQHLEGGLTVAEMAAATVQTSDNTAANQLMARLGGP -AGLTAFARSIGNRTFRLDRWETALNSAIPGDPRDTDTPAGMGTSLQALVLGTALGPPQRQ -RLQDWLIGTTTGDRRVRAGVPSGWRVGDKTGTCGYGTANDVAVLWPPDRAPIVLAVFHTQ -ADPAAAAQDGVIAEAAAIVAGAf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia caishijiensis TaxID=184756 RepID=UPI000833BA8D -----TTQFAALESKYGARLGLSVTDTGSGATV-AYRADERFPIASTFKGLACGALLQAHP -LSTGYFDQVVHYTAADLVEYSPETEKHVDTGMTVAALCHATITLSDNTAGNLVLRLLGGP -AGFTAFLRTLGDNVTRLDRWETELNTAVPGDERDTTTPAALAADYRALVVGNALAEPERA -QLAEWLKANTTGGKRIEAGLPADWIVGDKTGSPAYGSALDVAVAWPPNRPPLVLAVLSTK -SEQDAEPSNELLAEASRAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009955981 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLKKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A1S1U7I8_9BURK ---AAHTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAILAAAVLARSV -SQPGLLDQHVRFEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLENSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013D8DEF3 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRHSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNRNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA -LLTDWLVRNTTGDRRIRAGAPRGWKVGDKTGSGEWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDALVAEAARRVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. SG570 TaxID=2587113 RepID=UPI001445458C ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP -AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSFSDIAVVWPPDRGPILVTTFVAE -GTAPAKDIEAVFADVGKIVT--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A1Z2LE20_9ACTN -----SLRLAELEREHDARVGVFGHHVRTGRTV-RYRAGETFPMCSVFKTLAAAAVLRDLD -RDGEFLAKRLRYTRQDVDEWAPETGKHIADGMTVAELCDAALTRSDNAAANLLLRELGGP -AAVTRFCRSVGDRTTRLDRWEPELNSAEPWRVEDTTTPYAIGRTYARLVLGNALSPRDRR -QLTAWLRANTTSDHRFREGLPAGWTLGDKTGTGDYGTANDVGIAWAPDGSPVVLAVLTTK -HTQEAKADDALIADVARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4U2NBZ4_BACCE ------DSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC0BBE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYTSTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces alboniger TaxID=132473 RepID=A0A5J6HUU0_STRAD ---DARRRLRELEKGYPGRIGLHALNTGTGATL-GYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDTVIRYGRDDLVTYSPRCEMHLATGMTVRELCDATVTYSDNAAGNLLMRRIGGP -SGITRFARSLGDPHTRLDRWETDLNTNIPGDPRDTTTPAAMTANLRKLVLGDALAPLDRD -QLIRWLVENTTGDARIRAGLPEGWRVGDKTGSPAYGGVNDIAVAWPPKGAPLIISVYTTR -LDPDTPGEDRIAADMTRVAVD-- ->[subseq from] Beta-lactamase (Putative hydrolase) n=1 Tax=Bacillus sp. 71 TaxID=593090 RepID=A0A654B0N2_9BACI -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPLILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CB01635 TaxID=2020326 RepID=A0A2M9JS88_9ACTN ----ARRRLRELEAGYPGRIGVHALHTGTGAVL-AHRAHERFAIASTFKVLAASAILHRAR -QEPGLLDALIRYGRDDLVAASPRTEMHLETGMTVRELCDAAITYSDNTAANLLMRRIGGP -AGVTAFARSLGDSVTRLDRWETDLNTNIPGDRRDTTTPAAMTADLRALVLGDALHPLDRG -QLTRWLVENTTGDKRIRAGLPPGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVISVYTTR -LDADTPGEDRIAADITRIAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI001115832F -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDEMIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0010FBEB2D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRTGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BC3B98 -----TPQFAELETTYDARLGVFAVDTRSGRSV-SHREGERFPMASTFKGLACGALLRDHP -LSTGYFDQVIHFPASDLVEYSPVTETRVETGMTVAELCDAAITVSDNTAGNQLLKLLGGP -EGFTAFLRSIGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRTLVVGDTLAEPERA -QLTSWLVANTTGDTRIRAGLPGDWKVADKTGSPAYGSALDVAVTWPPGRAPIVIAVMSTK -SEQDAEPDNALLADATRAAI--- ->[subseq from] inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-32 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00093994C8 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGMANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD8B3B --kDIDKQLAALEKQTGGRLGVYVLDTKTKASF-AHRQDERFAMCSTFKAVAAAFVLARVD -KGEERLDRRISISKKHLLSYSPVVEKHVGGGMTVGELCDATVTYSDNAAANLLLASFGGP -KGLTDWLRSIGDATTRLDRIEPELNEAKIGDPRDTTTPKAMTQTLGTLLLQDVLSPASRD -QFSAWLVANTTGDRRLRAGLPKAWTIGEKTGTSGRGEAGDIGFMRPVEGHTILASVYIAE -GKKPTEELEPVFGEVGKLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E9NST5_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMAIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0XSK5_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DDKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI000761353D -----DEKFAEIEKEFNARLGVYAIDTGTNQRL-QYNPDDRFAYASTFKVLASAILLKQNS ---IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP -EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE -LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH -EEADAEYDDALIAKAAEIALN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5N2_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTERHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia aggregata TaxID=187304 RepID=A0A0M6Y628_9RHOB ----LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGNALSSTARA -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharomonospora saliphila TaxID=369829 RepID=UPI0012FC4322 -----RARLHALERRHGARLGVYAANVRTGATV-SHRAGERFALCSTFKPLAAAAILRDRD -HHGEFLARTIHYTEHDLVEYSPVTEEHVGTGMRVDALCAAAIRYSDNTAGNLLLRQIGGP -AGLTAFCRSLGDPVTRLDRWETDLNSALPGDPRDTTTPAAIGRDYARLVLGDALGREDNA -LLTEWLLGNTTSGDRFRAGLPDGWRIGDKTGSGDYGTANDVGLAWTTLGTPLVLAVLSTK -HAPEADWDDELIAETARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Leaf406 TaxID=1736368 RepID=A0A0Q6L611_9BACI ------ETFANIEDKYDARVGIYAIDTGSDRTI-DYRSEERFAFTSTYKALAAALVLKQNT ---MEELEEVITYTEDDLVSYSPITEKHVETGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFKQSLREIGDDVTQADRYETALNEFTPGDPRDTSTPEALATSLQGFAVGDLLSDDKRK -ILIDWMKGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIIMAIMTRH -DTEDADYDDALIAEVAEVTLE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. RAU2J TaxID=1938810 RepID=A0A495TY53_9BURK --eAIRERLARIEAASGGRLGVSIVDTTTSLHA-GLRADERFPMCSTFKLLAAGAVLTRVD -LGQEDLQRRVVFSASDLVPNSPGTSRHTRELMSIGELCKAALTLSDNTAANLLLASFGGP -AAVTAFARSLGDGITRLDRIEPALNEAIPGDPRDTTTPNAMLGNLRELVLGEHLSAASRT -QLLAWLVANQTGGSRLRAKLPEDWGVGDKTGTGERGTANDIAILWPPGRGPVLVTVYLTE -ADGDAARSNAAIANVGALVAE-- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A4D7HIG1_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNKVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Duganella sp. FT27W TaxID=2654636 RepID=UPI00128CD8E8 -----AAQLARLEADTRGRLGVAAINTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP ----SLLDKRIRYTAADLVSHSPVTEQNLADGMTVGELCAATIQYSDNAAANLLMKQIKGP -AGVTAYARAIGDKAFRLDRWETELNTAIPGDPRDTTTPLAMMKSLQSFTLGPALTVDKRK -LMTEWLIGNTTGDTRIRAGVPYDWQVGDKTGTGSYGSTIDIGVVWPTGKAPVVIALYFTQ -PGKDDKANSEILASAARVVVEAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC322MFChir4.1 TaxID=1449045 RepID=UPI0009DF2EE5 ---ATHQEFAQLEKKFDARLGVYAIDTGTNRTV-SYKQNERFAFASTYKALAAGAVLLQNP ---IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNFLFKELDGP -KGFEKALKQIGDGVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTVGNVLPADKRK -ILTDWMRRNATGDKLIRAGLPKDWEVADKSGAGSYGTRNDIAIVWPPNRKPIIIAILSSR -DTKDATYDNELIAQTATITIN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2C2T5T1_BACCE ---ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP ---IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP -EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTVGNALPADKRK -ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYDNELIAQAATITIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Leaf75 TaxID=1736235 RepID=A0A0Q6I169_9BACI -----KHHFVKLEDKFDARLGVFALDTSTNQTV-TYRADERFIYASTSKALAVGALLQQKT ---IDDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAMNLILKQIGGP -NGLEKSLRDVGDNVTMPEQFEPELNDVKPGETHDTSTPRALATSLQSFTLGDALPVEKRG -LLIDWMKRNTTGDSLIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPPKGDPIMLAILSSR -DKKDANYNDKLIAEATKEVINAy ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. GV004 TaxID=2135501 RepID=A0A2W7IKT7_9BURK ----AEAQLAELERACGGRLGVAGFHTASGARV-LHRAHERFPLCSTFKLMLSATVLERSA -KDPGLLSRRLRYGQADLIANSPVTEQHVATGMSVAELCAATLQYSDNAAANVLLRQLGGP -GEVTAFARRIGDAAFRLDRTEPELNTSIPGDPRDTTTPAAMSDSVQRLVLGDALGAPQRE -QLKAWLLGNTTSKERFLAGVPAGWKVADKTGAGSYGSNNDVGVLWPPAGAPLVLSVYLTF -AQKDAKTRNDVVAAATRIAV--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0012988D38 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGNKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter rhizosphaerae TaxID=2010972 RepID=A0A561NXD1_9CAUL -----SRSIVALEARSGGRLGVAVLDTANGKTF-AHRGDERFAMCSTFKALVAGLVLKRVD -QGQERLDRRIPYGPGVLLAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLHTFGGP -PALTAFLRGLGDTATRLDGYEPGLNVVRPGEIHDTTSPSAMLATLRALTLGPVLSAASRQ -QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWSVGTTNDIAVTWPPRRPPLLITAYLSR -STLDDDGRNAVIAEVARLVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2C1QKT9_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATAVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000744C265 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVRPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI000E5BABC8 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALSNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI0006E57649 ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLARQVKIRASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=UPI0014282CE5 ----ADSEFASLETEYGARLGVYALDTGSGRTV-AHRADERFAYASTLKSLAAGAVLHAVP ---PAGLDERITYTRADLVPNSPVAEQHVDGGMTLRETLDAAVRYSDNTAANLLFAKLGGP -KGLERNLRDLGDTVTQVDRTEPDLNEATPGDPRDTSTPTAFAADLRQYVLGPVLTDPARA -LLADMLRANTTGAELIRAGVPAGWVVGDKTGLAAYGSRNDVAVLWPPNAAPIVLVVFTTR -PTEDATYDNALIAKAAAAAVQ-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B42D680 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAANLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. YIM 132548 TaxID=2615211 RepID=UPI00124723C3 --eALRRHFAEIEGRSASRLGVAVLDRRTGLRA-GHRADERFPLCSTFKLLAAAAVLARVD -AGRESLERRVVFSAADLVPYSPATERRVGADMPLDEICAAAITLSDNTAGNLMLGAIDGP -AGLTAYLRSLGDPVTRLDRTEPDLNEARPGDPRDTTSPAAMLDTLQRLLLGPALSAASRA -RLVGWLRDNETGETRLRARLPRDWRVGDKTGTGENGTANDVGILSPPGGD-ILVAAYLTE -STAPSQARNATIAEVGQAL---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XQ78_BACCE -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5WWN2_9BACT ---DAAARVAAIEARIGGRIGVAALDTSNGKRF-DHRAEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVSYGAKDILEHAPVTKERLKDAMTLGALCEAAIEQSDNTAANLLLDAIGGP -ASLTQFARKLGDQITRLDRKEPDLNSAIAGDERDTTTPGAMCLDMQRLLVASVLSESSRR -QLEDWLLRNKTGGLMIRAGVPKTWSVGDKSGRCANGATNDIAIIRPPDRAPILLAIYSVG -STAPANNREMAIAEVAKIVAELf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI000A211530 ---NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGQESLERRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKEDPRDTTAPDAMLDTLGNLTLGSVLAEPSSE -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVGKMITE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B5QQ29_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDTKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0006AD7971 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQTFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A385TW86_PAELA ------------AAEDGIELSVGIQDLSGGGKI-QVGSSDVYYAASTIKIAIVTALMQDIE -AGKYALEQIIQVQPEQVVGGAGSLKDKFPLDITIESLARLMITQSDNTATNALIDLL-GF -ERINAFIEEQGFETMQLGRKMMTPAKS--PAADNYVDGEELLTLLERIYAGEILTAKSRD -QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-AAVTVLTKV -TKKAQELGNPIVQRAAKAVYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A385TW86_PAELA -------------EDKGIRVSVGLKDLSGDREL-LLGSRQSYMPASTIKMALVSALMKEVD -AGRLTLEETVKVEKEDVVGGTGSLQKETPQDVTIERLAKLMITQSDNTATNVLIDVV-GL -DEVQNLMDELGLDVMHLGRKMFAAA--PTPEQDNYIDAEDLVHLLAYIHSGSFLSDNSRD -QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLLPGRE-IAISVLTEV -TTEAQAIGNPVVQEIAKAVYE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0U2TZA9_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B454DE9 -----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 75 TaxID=2135628 RepID=A0A4R8KLK0_9BURK ---AAHTQLAALEQAAGGRLGVAAWRQGSELRI-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8ER34_BACCE -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter sp. BW6 TaxID=2592624 RepID=A0A5D0VRR0_9ALTE -hsSLIQTVARIAGEIEAQVGFAAYDLESGQRW-EYQADQRFAMSSTFKTLACAALLHRVD -AGQESLERTVSFSESDLVTYSPITEKYAGGQMTLSDLCEAALTMSDNTAANLVLRALGGP -EKVTSFARDLGDDITRLDRWETELNAAVPGDNRDTTTPNAMVKSLQNLLLGDVLSGKSRD -QLHDWLKRNQVADGLFRAAVPEGWIVADRTGAGGFGSRSITAINWPPERQPIVVALYLTQ -TEASFSERNEAITEIGEAIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium fredii TaxID=380 RepID=UPI00059560EE ---DVTELLAELEKRTGGRLGVAVLDTETNTSF-GYRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKDVLLPHSPVTEKHVGGEMTIAELCDAAITISDNAAGNLLLESFGGP -AGLTSWLRSIGDEATRLDRMEPDLNEASFGDPRDTTTPAAMIGTLGKLGFGSVLSESSRQ -QLIEWMVANTTGDARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPEGRGPILIAVYTGE -AKLRPAELNPIFAEIGRIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8X5_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQDDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATALRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas mucosa TaxID=207340 RepID=A0A379MZJ5_9PROT ----LPAVFAGIERRVGGRLGVAVLDTATGQRA-GHREAERFPLTSTFKLLAAAAVLSRVD -AGQARLDQRIRYGREKLVAYSPETEKHAGEEMTLAAICEAAVTLSDNTAGNLMLEQIGGP -AGLTAWLRSIGDTVTRLDRWETALNEAEPGDPRDTTSPAAMLASLQRVTLGEALSVGGQA -HLTGWLRANKTGDKRLRAGLPGGWQAGDKTGVGERGTNNDAGLLWPPGEAPILVAAYSTG -GTAPSTERDAALAEVAAAIVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8S3_9BACT ------------EDQLGARVGYIELDLNGGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A0Q6TXS4_9CAUL ---ALNSRINDLEQRSGGRLGVAVLDTQTGRRF-AWRGDDRFRMCSTFKMPLAAAVLRRVD -QGREQLDRRITYGRDVLMGNSPVVEKHLGEGMMVAALCEATITWSDNASANLLLDALGGP -ASLTRFLRAIGDQTTRCDRREPELNTGAPDDPRDTTTPSAILGTWKTLLLGDALSPASRK -QLTAWLVANRTGNKRLRAGLPRGWRVGDKTGNNGKDTTNDIAIAWPRGRKPILIAAFHDR -GSADDDARNAVHAELAHAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. NBRC 111119 TaxID=1661034 RepID=UPI0007618871 ---DIDSDLSTVEHSFKVTLGVWAIDTASGKTV-AYRAEDRFAFCSTFKVILAAAILAKSA -EDQALLDRRITYAPDQLVTYSPITEQHVQAGMTVRELCAAALQYSDNTAGNLLLELVGGP -PGLTAYARTLGDPAFRSDRNEPSLNTALPGDPRDTTTPLAMGVTLQKLLLGSGLAEGARQ -QLQGWLKGNTTGDKRIRAGVPQGWLVGDKTGSGDYGVANDVAVIWPPGKAPWIVVVFSRA -EAKASEWNNDAIAASMKAVV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8S8_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCGAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD93FE7 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGGLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKEFAVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKSAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00031461E4 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGKTHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis YBT-1518 TaxID=529122 RepID=V5MB54_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IATLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNTTGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. J37 TaxID=935837 RepID=UPI0004799EE3 ----SQDEFSKLEEKYDAKLGVYALDTGTDETI-SYRPDERFAYASTSKALAVGVLLQQKS ---IEDLNEKITYSRDDLVTYSPITEEHVDTGMTLRDLSDASLRYSDNTAANLIFETIGGP -EEFKHALRQIGDDVTNPERMEPELNEVAPGETHDTSTAKALAASLQTFALEDALPPEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAASYGTRNDIAIIWPPNEDPIVLTILSSR -NEKDAPYDDELIAEATKVVLAAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-4 TaxID=1053203 RepID=J8CUJ7_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKLLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B51DF1 -----NHNFAKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFACASTHKALAVGALLQQKS ---IEELNQRITYTRGDLVNYNPITEKHVDTGMALKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEEMGDNVTNPERFEPDLNEVHPGETHDTSTPKALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEATKVVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas phaseoli TaxID=1985254 RepID=UPI0003200A18 ---MLQAQWAQIERGTGGRLGVCLLDSATGKRL-GQREDERFPMCSTFKFVLVAAVLQRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTRWMIDNRTGDDCLRAGLAADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. SLB01 TaxID=2610882 RepID=UPI001245E1B6 ---AAQTQLAALEKAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKDLVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATHIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Yersinia frederiksenii TaxID=29484 RepID=A0A0T9Q3R2_YERFR ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLVAAVLGHSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -EMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTPPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAPTDWVIGDKTGSGDYGTTNDVAVLWQAKGAPLVLVVYFTQ -LKKAAEPRRDVLAAATKIVLAH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8U3_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDGRDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 64 TaxID=2035208 RepID=A0A2N0HYE9_9BURK -----HTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTMFQLERWETELNSAIPGEVRDTASPASMAHSLQQVLLGNSLPAAQRQ -QLDAWMRGNTTGDKRIRAGVPAGWKVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=A0A423CK81_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERK-------------- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus temperata TaxID=574560 RepID=A0A4R7Q3X4_PHOTE ---SLHQQLAELENSTKGRLGVTLINTANGQEI-QYRGNERFPFCSTFKLILVATVLHKSM -SQSKLLAKHINYHESDLLSYAPIAHKNLNQGMSITQLCAATLQYSDNTAANLLIKELGGV -EAVNHFTQSLGDPAFRLDRWEPDLNSAIPDDPRDTTTPAAMAASVKKIVLGETLAAPQRE -QLTVWLKGNTTGNASIRAGAPVGWVVGDKTGSGDYGTNNDVAVLWPPEGSPVILAVYFTQ -HQKDAESRRDVLASATRLVMAH- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BCC1885 TaxID=2562669 RepID=UPI0011821F15 ---SVAAQLAKLEHEAGGRLGVCLLNTADGTWL-GHRADERFPFCSTFKVILSGAILARST -QTAGLLQRRIRYTQSDLVHYSPVSETHITDGMTVAELCAAALQYSDNTAANQLIKLLGGT -AAVTAYARLIGNDVFRLDRTETSLNDAVPGDPRDTATPASMVRSLQALTLGEALPVAQRA -QLIEWLRGNRTGAHRIAAALPAGWTIGDKTGTGDYGTANDLALIWPPARPPLVLGIYHTQ -AAQDAQPRDEVIAAAARIVV--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI00044F85F2 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKPLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVPRLDRWETELNEALPGDARDTTPPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWVIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J8AYM5_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF91AF9 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFTLGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1G4EHS1_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0005C54B12 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IATLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNTTGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7VZV4_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009BE1196 -hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYAKEDLVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=unclassified Bacillus TaxID=185979 RepID=UPI00124E32E6 ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MCT4_9BACI ----MDIKFAALENQFGARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYTKDDLVTYSPITEKHVATGMNLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQMGDSVTTSERYETELNEAKPEDTRDTSTPKALATSLRAYTVGNALSSDKQK -ILIEWLQGNTTGAKLIRAGVPKDWIVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKIAVD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2H2WCK0_BACCE --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP -KGFEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar vazensis TaxID=180867 RepID=A0A243CP90_BACTU ----VNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IENLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. X TaxID=2048901 RepID=A0A2G5REK9_9CAUL --kALSSRINELERASGGRIGVAVLDTHDDRRF-AWRGDERFRMCSTIKAPLSAAILRRVD -QGRERLDRRVTYGPEVLMGNSPIVEKHVQDGMTIGQLCEATITLSDNAAANLLFEALGGP -AALTRFLRAVGDQTTRSDRPEPELNTGAPDDPRDTTTPAAMVATWKALLLDDALSPASRQ -QLRAWLIANKTGNRRLRAGLPRGWRVGDKTGNNGKDITNDVAIAWPPGREPVIIAAFHDR -GG-DDDARNSVHAEVARAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=A0A4Q0WSG1_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. HUB-I-004 TaxID=2568878 RepID=A0A4S4HTJ3_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKELTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWGVADKSGAGSYGTRNDIAIVWPPNKASIIIAILSSK -DEKGATYDNQLIAEAAEVIVNAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001145C5A0 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDPVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=UPI000BA295F9 -hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD -AGLEQLDRRIKYRQNDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP -KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILSVKSRQ -QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE -TQATMDERNKQIAEIGASLIKNw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FAB9_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKPGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. 011 TaxID=2171494 RepID=A0A2T7HB33_9RHOB ----LAAAVDHIGSRLPARVGVAVLDTETGKSW-SHLGDERFPLNSTFKAFLCAALLDKGE -AGDLDPGSRVKIHREDLVSYSPVTEKKVGSGMTLLELCEATVTISDNAAANLVFEQIGGP -DGLNGFLRRIGDMHTRLDRLEPGLNSGHPGDDRDTTTPVAAAATLEKLLLGDALSTGARA -QLIRWMEGNKVGDSTLRAGLPQEWRIADKTGAGGNGSRNDIGVIWPTGRAPVVIAVYITG -TSASFEARNAAIAEIGAALAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF56371 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Duganella sp. Leaf126 TaxID=1736266 RepID=A0A0Q5DM64_9BURK -----AAQLARLETDSKGRLGVAAINTADGAIL-SHRGDERFPLCSSFKAMLAAAILHQEP ----SLLDRRIRYKAADLVTYSPVTGQNLADGMTVGELCAAAIQYSDNTAANLLMKLVKGP -AGVTAFARTIGDKAFRLDRWETDLSTAIPGDPRDTTTPLAMMKSLQGVTLGPALTVDKRK -QLTEWLVGNTTGDTRIRAGVPFDWQVGDKTGTGAHGTTIDIGVVWPPGKAPVVMALYFTQ -PGRDDAANAEILAAAARVVVEAf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8VQV7_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSPRSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGQ------ ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella quasivariicola TaxID=2026240 RepID=UPI000E2CF52B ------EQIKISESQLSGRVGYVEMDLASGRTLaAWRADERFPLTSTFKVLLCGAVLARVD -AGVERLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITMSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRRETQLNEALPGDVRDTTTPASMAATLRKLLTAKHLSARSQQ -QLVQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD -TPATIAERNQQIAAIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001427AB38 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKTIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8S6_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAASLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AC44/96 TaxID=1841654 RepID=A0A1B9SP10_9RHIZ ---EIDRRIGALEKAIGGRIGVSAIDTQTNISF-GYRETESFPMCSTFKVLAAGFVLARVD -KGEENLERRVVYDKDKLVTHSPETEKHVGGEMSVGELCQAAITQSDNTAGNLLLESFGGP -KELTNWLRTVGDGSTRLDRWETDLNEAKKGDQRDTTTPDAMLDTLGNLTLGSVLSEPSQN -KLVEWMVANTTGGTRLRTGLPDTWKIGDKTGTGNNGTAADIAVAWPPGHGPILMTVYVAD -ATAEISEINAIFGEVGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D0DC1F ---EIDRRIGALEKRIGGRIGVSVIDTQTNISF-GYRETETFPMFSTVKVLAAAMVLSRVD -KGEENLERRVVYDKSQLIDYSPETEKHIGGEMSVGELCKAAITLSDNTAANLLLETLGGP -KELTNWLRTLGDGSTRLDRIEPDLNEAKKDDPRDTTTPDAMLDTLGNLTLGTVLSEPSQN -TLVEWMVANTTGNERLRKGLPDGWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYINE -ATATTAEINPVFGEVAAIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D9UT59_BACMY ----TYKEFFQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFSFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00046F965E ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADERFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI000836A71B -------RLRALERKHGARLGVYALDTGTGGTV-AYRADERFAFCSTFKALAAAAVLHRNP ---LSHLDTRVTYTEADVNSISPITRDHVATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -RKLTAYLRELGDSVSRMDNYEPELNSDRPKDPRDTTTPRAIASDYRELVLGDALTADKRA -LLKGWLVRNTTGDERIRAGLPKGWKVADKTGTGNYGRVNDIAVVWPPHAAPLVLAVMSDR -RGYNAPRENVLIAEAARQVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0007C1D88D -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A0B5S8D6_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 11 TaxID=1416808 RepID=A0A261UE73_9BORD -------EYAHLERAHRRRLGVYAVDTATGREV-TYRAHERFAFCSTFKAVLAGAILSQDA -AQPGLLDQRILYTAHELASYSPVTEKHVHGGMTIAQLCAAAIQYSDNTAANLLLHRLGGP -RALTAYARGLGNPTFRLDRFETALNTSIPGDERDTSTPADMARTLETLVLGDALPPGARA -RLKTWLLGNKTGDRRIRAAVPPGWQVADKTGTGDYASANDFGVIWPADRPPVVLAIYTAS -RDPHAKADESLIAEAARIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb56 TaxID=1827287 RepID=A0A2S9I2B4_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus penneri ATCC 35198 TaxID=471881 RepID=C0B2Q3_9GAMM -----------LKKYNQGRLGVALINTEDNSQI-TYRGEERFAMASTSKVMAVAAVLKESE -KQAGLLDKNIAIKKSDLVAYSPITEKHLVTGMSLAQLSAATLQYSDNTAMNKILDYLGGP -SSVTQFARSINDVTYRLDRKEPELNTAIHGDPRDTTSPIAMAKSLQALTLGDALGQSQRQ -QLVTWLKGNTTGDHSIKAGLPKHWIVGDKTGSGDYGTTNDIAVIWPENHAPLILVVYFTQ -QEKDAKYRKDIIAKATEIVTKEf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BECE3D4 -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKAS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3U3H6_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKLLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-1 TaxID=1053201 RepID=J9C1S8_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG5X1-1 TaxID=1053189 RepID=J8AYF6_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. DMF TaxID=400837 RepID=A0A4Y8NS21_9RHOB ---NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLERKS ---LEELDEVITYTRDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLMLEELGGP -EGFEAALKEIGDTVTKPERFETDLNEAEPGDIRDTSTPKALAASLQKVLIGDFLTEEKRN -ILTEWMRGNATGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR -DSKDAEYDNALIAEAAEMTIK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Leaf453 TaxID=1736380 RepID=A0A0Q6H772_9RHIZ ---DADVRLAALEKATGGRLGVSVIDVAMNISF-GRRQDERFAMCSTFKMLAAACILARVD -NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP -EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKLLLDDALSEKSRD -QLTAWLVGNKTGDKRLRAGLPKGWTVGDKTGTSATGAIGDVAIVWPSPNRPILITAYIAE -ATKPAKELEYIFAEIGKMV---- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000E0A5B5C -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRHSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA -LLTDWLVRNTTGDRRIRAGAPRGWKVGDKTGSGEWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A1B3ISJ2_CITFR -----------------------NWDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI00124D7F77 -----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDAGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDIVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Limnobaculum parvum TaxID=2172103 RepID=A0A2Y9TV69_9ENTR ----IQHNLADLEKSTGGRLGVVLINTADNSRI-AYRGDERFPMCSTSKMMVVSGVLKQSE -VQKDLLNKQVDIRESDLVNYNPITEKRLNTKMSLAELSAATLQYSDNAAMNKLIAQLGGT -KKATAFARSIGDTAFRLDRTEPTLNTAIPGDKRDTTTPLAMAASLQKLTLGDALAAPQRA -QLVEWLKGNTTGAASIRAGLPAEWVVGDKTGSGSYGTTNDIAVIWPKDKAPLILVTYFTQ -NDKEAESRREVLASAAKIVTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI000648410E ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP -AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSFADIAVVWPPDRGPILVTTFVAE -GTAPAKDIEAVFADVGKIVT--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. 491mf TaxID=1761755 RepID=A0A1I1HUZ8_9BACI ---ATHQEFAQLEKKFDARLGVYAIDTGTNRTV-SYKQNERFAFASTYKALAAGAVLLQNP ---IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNFLFKELDGP -KGFEKALKQIGDGVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTVGNVLPADKRK -ILTDWMRGNATGDKLIRAGLPKDWEVADKSGAGSYGTRNDIAIVWPPNRKPIIIAILSSR -DTKDATYDNELIAQTATITIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus pseudomycoides TaxID=64104 RepID=UPI000BECCF80 ---TVNHSFAKLEKEFDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDERIVYTSEELVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRAIGDTITNPERFEPELNEVPPGDTHDTSTPKALATSLQAFALGDVLSTEKRE -LLIDWMKRNTTGGNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=A0A1J9UUJ4_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKRSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=A0A4V7TLS1_BACAM -----KQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNNVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTKDVNYDNALIAEAAKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. 9096 TaxID=1500894 RepID=UPI0005694A80 -------GFAALEREFGGELGVAAIDGASGRTI-GYRQDRRFPMCSTFKTVLVAAILACAE -REPGLLERQVALPKQVFVNYSPVTGKHAGGALSVAELCAAALQYSDNTAANALLREVNGP -AALTRYARTLGDTDFRLDRWETELNSAIPGDPRDTTTPLAMARTLRTLLLGDGLAPDAQA -RLRAWMLGNTTGKDRIRAAAPAGWKVADKTGTGSYGSAGDIAVLFPPQRAPVVLAIYTRR -AAKDAQGRSDIIARAARIALE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A1E8ALW7_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -LLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. vasculorum TaxID=325777 RepID=A0A098PXI9_9XANT ---ELREQWARIEQGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVKIHTSDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTALLRGIGDARTRTDRYEPQMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAQAVAAWw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001427A948 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2A8QC79_BACCE -----NDSFAKLEKEYDAKLGIYALDTGTNQTF-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A454M7S1_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFASGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter persicus TaxID=930118 RepID=A0A1I3SAM0_9ALTE ---SLIKTVERIADELGARVGFSAYDVESDQHW-EYHADQRFAMSSTFKTLACAALLQRVD -AGQENLDRKVSFSESDLVTYSPVTEKYAGGQLTLSDLCEAALTMSDNTAANLILRVLGGP -AQVTSFARGLGDGVTRLDRWETELNEAAPSDQRDTTTPNAMVKNLQSLLLGDALSVKSRD -QLRDWLERNQVADGLFRAVVPEGWIVADRTGAGGFGSRSITAIIWPPERQPIIVALYLTE -TEASFSKRNDAIAEIGKALI--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000E4B10E6 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD115 TaxID=1053230 RepID=J8KM50_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYVLGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Alteromonadaceae bacterium TaxID=1916082 RepID=A0A2E5MQ19_9ALTE ----LIATVDRTANELQANVGFAAYDLESGQRW-EYQADQRFPLSSTFKTLACAALLHRVD -AGDENLDREVSVSKSDIVTYSPVTETFAGGQMTLAALCEAALTMSDNTAANLILRALGGP -AEVTAFARFLKDDVTRLDRWETELNDAAPGDQRDTTTPNAMVKNLQSLLLGDVLSTESRA -QLLDWLERNQVADGLFRAVVPEGWVVADRTGAGGFGSRSITAIIWPPEREPIIVALYITQ -TDASFPARNEAIAEIGKAIV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 5mfcol3.1 TaxID=1761756 RepID=A0A1I4CVE9_9BACI --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -GEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF44ACF ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPSNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0007E08E73 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPKHFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKKNTTGDSLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase n=2 Tax=Variovorax TaxID=34072 RepID=A0A0P9AEC2_VARPD ---DAEARLAALERDCGGRLGVHALDTASGARI-AHRGNELFPMCSTFKLMLAAAILQRGT -AEPALLERRLSYTRAHLLPNSPITEKHLADGMTVAELCAATLQYSDNAAANLLLHQLGGP -AGVTAYARSIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALAAPQRA -RLEAWLRGNTTSKERFLAGVPAGWAVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF -PGKGAKTRNDVVASAVRIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus caeni TaxID=405946 RepID=A0A0N0M595_9BACI ---KIDNQFSQLEEEFDAELGVYAVDTETNQAI-EYQSEERFAFASTYKALAAAIVLQQNS ---MEELNQVITYTKEDLVPYSPVTEKHVDSGMTLLNLAEAAVRTSDNTAGNLLFNAIGGP -KEFEQTLREIGDNDTQAERYEPDLNQFSPEDPRDTSTPKALATSLQAFALGDLLPNEKRE -QFTDWLQGNATGDTLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNREPIVIAIMSRH -DTEDATYDDALIAEAVKIALN-- ->[subseq from] Beta-lactamase SHV-1 n=2 Tax=Klebsiella TaxID=570 RepID=A0A6C2V8W7_9ENTR ------EQIKISESQLSGRVGYVEMDLASGRTLaAWRADERFPLTSTFKVLLCGAVLARVD -AGVERLDRRIHYRQQDLVAYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLDTLGGP -AGLTAFLRTIGDNVTRLDRRETQLNEALPGDVRDTTTPASMAATLRKLLTAKHLSARSQQ -QLVQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKAERIVVIYMRD -TPATIAERNQQIAAIGAALIEHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F966_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIAVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=B4YF43_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGAA----- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI001145431F --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0013D07DCF --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00065BCA48 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001290702E --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---INSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS059628 TaxID=2033508 RepID=A0A2B4FK75_9BACI --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVINFSKEDLVDYSPVTEKHVDTGMTLGKIAEAAVRYSDNTAGNILFHQIGGP -KGYENALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPIQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSNK -DEKGATYDNQLIAEAAEVVVNAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDF781A ---DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP -AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSVLAEDSAN -QLVDWMVANTTGGARLRAGLPSGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE -MTVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDED4F2 ---DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP -AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSVLAEDSAN -QLVDWMVANTTGGARLRAGLPSGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE -MTVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF58519 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2CSH4_STRVZ ---DAARRLRALEESYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDVLIRYGRDDLITYSPRTEMHLETGMTVRELCDATITYSDNSAANLLMRRIGGP -AGVTEFARSLGDSRTRLDRWETDLNTNIPGDRRDTTTPAAMTANLRKLVLGKALHPLDRG -QLTRWLVENTTGDKRIRAGVPKEWRVGDKTGSPAYGGVNDVAVAWPPKQAPLVISVYTTR -LDPDTPGEDRIAEDITRIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium americanum CCGM7 TaxID=1408224 RepID=A0A1L3L1C2_9RHIZ ---DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGDMTVAELCDAAVTISDNAAANLLLESFGGP -AGLTSWLRSIGDRTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR -QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE -AKVEPAELNPVFAEVGKIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2K8TR97_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQSFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B401C1 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTVKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRSGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNKLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00119CB1E0 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQKS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8V7_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGLLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI0014197402 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGISLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Phyllobacteriaceae TaxID=69277 RepID=Q11G68_CHESB -----SERLAALEKRSGGRLGVAILDTRTGLKA-THRADERFAMCSTFKALAAAAVLARAD -AGKEDLNRRISYGREKLIFWSPVTKNHADGPMTLAELCEAAVTMSDNTAGNLLLESLGGP -KGLTAFFRSLGDEVSRLDRWEPELNDVPPGDLRDTTTPEAMLGSLRSVVLGDALSPNSRQ -RLAGWLIGCKTGDKRLRAGFPAGWTVGDKTGTGST-VASDIAVAWARSGATLVVSAYLEA -PQLPAPKRDGIFREIGEIAS--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA4-10 TaxID=1053206 RepID=J8DP84_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodoferax sp. YR267 TaxID=2135500 RepID=A0A2U0YV57_9BURK ---SASQQLQALETAAAGRLGVAAFGAGSARLL--HRAGERFPACSTFKLVLASAILARSV -QDTGLLQQRIHYAASDLVSYSPITEKHVASGQTVAELCAAALQYSDNSASNLLMRLLGGP -PAVTAFAHAIGDSSFRLDRWETDLNSAIPGDPRDTCTPAGMAHSLQALLLGDALALPQRR -QLKDWMLGNTTGATRIRAGVPADWRVADKTGAGSYGTTNDIGVVWSPAGTPVVLAIYFTQ -PYQSAPMRNDVVAAATRIALQ-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243FFN1_BACTY --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIAEVTEVIVK-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF39861 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLITTIGGP -KELTAFMHNMGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola pv. guizotiae TaxID=487867 RepID=A0A2S7A6K2_9XANT ----LRAQWAEIERGSGGRLGISLLDSATGKRL-GRREDERFPMCSTFKFVLAAAVLQRVD -KGELTLAHRITIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGVTAFLRGIGDAHTRSDRHEPEMNRFALDDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGATCLRAGLPRGWKIGDKTGSNGSDTRNDIAIVWPPAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 166amftsu TaxID=1761753 RepID=UPI000B8234AF ---ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP ---IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP -EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALANDLKAFTVGNALPADKRK -ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYDNELIAQAATITIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFC1FD0 ------DSFVKLEKEFDAKLGIYALDTDMNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVVAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001443D68E -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B44EA1A -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00124EFB29 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQSFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C4DFB1_BACMY -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00114577AF --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF735B0 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLVILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus TaxID=1396 RepID=Q81DA0_BACCR --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4Q2K0_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus oncorhynchi TaxID=545501 RepID=A0A0A1MQB6_9BACI ----SEEVFKELEDEFDTRLGVYAIDTETNQTV-AYRADERFAYASTFKVLAAAAILQTAS ---REDLEKVITYTEDELVTYSPVTENHVDDGMKLKEIMEAAIRYSDNTAGNLLLEELGGP -DGLEERLREIGDETIEADRMEPDLNEAAPGDTKDTSTPKALAESLQKYVLSDLLSEDKRD -LLTDWMTGNESGDTLIRAGVPEGWEVIDKSGAGGYGTRNDIAVVWPPDHAPIVISILSSR -DTEDADFDDAVIAKAARGVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2T0DNI3_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A5C1FVF3_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSNERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001145DEA4 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens group TaxID=1938374 RepID=UPI001111F53B -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRVPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1G6IFW2_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPEHFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKKNTTGDSLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Chelativorans multitrophicus TaxID=449973 RepID=UPI00140C5E4B -----SERLAALEKRSGGRLGVAILDTRTGLKA-THRADERFAMCSTFKALAAAAVLARAD -AGKEDLNRRISYGREKLIFWSPVTKNHADGPMTLAELCEAAVTMSDNTAGNLLLESLGGP -KGLTAFFRSLGDEVSRLDRWEPELNDVPPGDLRDTTTPEAMLGSLRSVVLGDALSPNSRQ -RLAGWLIGCKTGDKRLRAGFPAGWTVGDKTGTGST-VASDIAVAWARSGATLVVSAYLEA -PQLPAPKRDGIFREIGEIAS--- ->[subseq from] OKP family class A broad-spectrum beta-lactamase n=1 Tax=Klebsiella quasipneumoniae TaxID=1463165 RepID=UPI001438455E ------EQIKISEGQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVGDP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0006203D79 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A2L2K0E5_9NOCA -------RFAELETTAGARVGVFAVDTGSERTV-AHREHERFPMASTFKGLACGALLREHP -LSTGYFDQVIHFSAAELVEYSPVTETRVETGMTVAELCDAAITVSDNTAGNQLLKLLGGP -QGFTAFLRSLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVDDVLGEPERA -QLTSWLVANTTGGTRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLTTK -SEQDAEPDNELVADATRAVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009CE5FF3 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVNDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI0005CB7D6D --qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A141RQC0_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A521NT36_9BURK ---DAEARLAALERDCGGRLGVHALDTGSGARI-AHRGNELFPMCSTFKLMLAAAILQRGT -AEPALLERRLSYTRAHLLPNSPITEKHLADGMTVAELCAATLQYSDNAAANLLMHQLGGP -AGVTAYARAIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALAAPQRA -RLEAWLRGNTTSKERFLAGVPAGWTVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF -PGKGAKTRNDVVASAVRIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. L-9-10 TaxID=1478131 RepID=A0A4V1VMC8_9ACTN -----AGELKELERTFDARLGVYAIDTGTGREV-AYRDGERFGYASTFKALAAGAVLRKYS ---LSGMDRVITYSKEDLVANSPVTEKHVETGMSLKELCDATIRYSDNTAANLLFDQLGGP -KGLQAVLRGIGDDVTLMERREPELSRWVPGDTRDTSTPRALAKDLRAFVLGDVLGKGERA -QLTEWLRTNTTGDELIRAGVPKGWVVGDKTGSGSHGARNDIAVVWPPDSAPIVMAIMSNR -PDKDAAYDNKLIAEAASVVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Aquincola tertiaricarbonis TaxID=391953 RepID=UPI000614A914 --------WAAIEAGVGGRLGVSVLDTGSGQVT-GHRLDERFPMCSTFKWLAAAHVLQRVD -AGLERLDRRIVYGPEVLIAHSPVTQRHADGSMTLAALCEATVTVSDNAAANLILQTLGGP -AGLTAFVRTLGDAHTRLDRTEPELNEATPGDPRDTTTPRAMAGALQRAVLGDALSPAGRQ -QLAAWLEAASTGFKRLRAAVPAGWRAGDKTGTGSRGTANDVAVFWPPAAPPLVVCAYLTD -SSAAPAQRDAALAEVGRQAVQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FBZ9_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDDMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD3C6A ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8Q3_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASQQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFAAEDF ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWKPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00110BCA4D ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIV----PNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2A8HEU7_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDALNEVIKFTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. CF142 TaxID=1144314 RepID=J2B1G2_9RHIZ --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRVTYGKEKLVTYSPETEKHAGGDMTMAEICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYMAE -TMVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A221BPV1_BACCE -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFALGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI000997F8E7 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPNGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. Root1472 TaxID=1736470 RepID=A0A0Q7WIF7_9CAUL ------RGMAALEARSGGRLGVAVLDTADGRTF-AYRGDERFAMCSTFKALVAGLVLKRVD -QGQERLDRRIVYGRNVLLAHSPATEKHVADGMTVGALCEATVTLSDNAAANILLYTFGGP -PALTAFLRGLGDKVTRLDGYEPNLNVVRPGELHDTTSPNAMLGALRALALGPVLSSASRQ -QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGDGTTNDIAVIWPPGRPPLLITAYLSR -STLADDGRNAVIAEVARLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BED7BD8 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDHVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0011AA8223 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMVLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Ensifer sp. LCM 4579 TaxID=1848292 RepID=A0A1S1TJR0_9RHIZ --dDVAKQLEELERQTGGRLGVSVLDTETNISF-GHRETERFAMCSTFKALAAACALARVD -RGEEALDRPITFGRDVLLPHSPVTEKHVGGNMTVAALCEAAITISDNAAANLLLESFGGP -AGLTSWLRSIGDETTRLDRMEPELNEAAFGDPRDTTTPAAILETLGKLAFGSVLSESSRQ -QLVGWMVANKTGDARLRAGLPKDWRIGDKTGTSMTGAVSDIGFAWPDGRRPILVAAYTGE -AKAPLDILNPVFAEIGGIIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT13W TaxID=2654252 RepID=UPI001264777E ---TAQTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQQVRYEKKELVTYSPITEKHLADGMTVAELCAATLQYSDNSAANFLMKILGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGEVRDTASPTSMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptoalloteichus hindustanus TaxID=2017 RepID=A0A1M5CIF5_STRHI ---AVHDELRELERQHGARLGVHATNTRTGATV-AYRAGERFPMCSTFKTLAAAAILRDLD -RDGEFLDRLIRYTEADIVENSVITAKRVATGMRIRELCWAAICHSDNTAGNLLLRQIGGP -AGVTRFCRSLGDPHTRLDRYEAELNTAIPGDPRDTTTPAAIGRDYRHLVLGDALNCQDRE -QLTAWLKANTTSSKRFRAALPPSWELGDKTGSGRYGTVNDVGVTWTPDGTPIVLAVLTTK -HEENATPDNELIVDTARLLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649UHG8_ECOLX --------LAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTASARQLGDETFRLDRTEPTLNTAIPGDPGDTTPPRAMAQTLRNLTLGKALGDSKRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLAS--------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AC74_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNXKAERIVVIYLRD -TPASMAERNQQI----------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C3E3J2_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HF66_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDEHDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus muralis TaxID=264697 RepID=A0A1B3XTP4_9BACI ------HDFAKLEEKFDAKLGIFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IKDLDQRINYTSDDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAGNLILKQLGGP -AGFKKALKEMGDDVTNPERIEPDLNEVNPGETHDTSTPRALASSLQALTLGDALPKEKRE -MFIDWMKRNTTGDALIRAGVPKDWAVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDAEYDDKLIAEATKEVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI000541A728 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRPDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVNDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VDM053 TaxID=1053249 RepID=R8PHP6_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C4DAE5_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAANLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8Q0_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAGLGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000E0F81C3 ---DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP -AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSVLAEDSAN -QLVDWMMANTTGAARLRAGLPSGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE -MTVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF47705 ------HSFAKLEKEYNAKLGIYALDTDTNKTV-AYHSDDRFAFASTSKSLAVGALLRTSS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREIGDTVTTSERFEPELNEVHPGETHDTSTPKAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B4PFL3_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -LLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=C2SKW4_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSNERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus necropolis TaxID=163877 RepID=A0A221MFF2_9BACI -----DEKFAQLENEFDARIGVYAIDTGTNQTV-KYHPDERFAYSSTFKVLAAAILLKQND ---IKDLEKVVTYTKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -DKFKQALRNIGDDVTQPERYETELNEFTPGNKRDTSTPSTMAINLKKVALGDFLPNEKRE -LLIDWMKGNATGDALIRAGAPQGWKVADKSGAGSYGTRNDIAIVWPPNREPIVIAVMSRH -DKENAEYNDALVAKAAEITL--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 7K534 TaxID=2530366 RepID=A0A4R4MQT2_9ACTN ---EVAKQIRRLERTRDMRIGAYAVDTGTGRAV-GHRMDETFPFASTFKAIACGAVLRKAR -SDPGLLDRVIRYKESDLSAHSPITEKHVKTGMTVADLCHATITQSDNTAGNLVLKQIGGP -AGFTAFLRSLGDQVTRSDRWEPGLNEWRPGEKRDTTAPRAWAGTLQALTVGDALAPADRK -QLTAWMKATVTGDKRIRAGLPDGWTAGDKTGTGGYGSANDIAIAWPPSGPPVVMAIMTTK -QTPDAAADEQAIARTTTILL--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. NZIPFR-PS5 TaxID=1230465 RepID=A0A2G4DUT6_9PSED ---AIAQQLAELERRHGGRLGVAMLDTSSQRLI-SHRGDERFALCSTFKCLAAACVLARVD -QKHEDLSRRILYSAEQLVAYSPTTELHAGGQLSVGSLCEAAMTLSDNTAANLLLDSVGGP -EGLTAWLRSIGDTQTRLDRREPGLNENRPDDLRDTTTPVAMLQTLNTLVLGEKLTPASRD -QLTAWLVNNQTGDKKLRAGIPVSWRVGDKTGSGANNASNDVAVIWPGERGPMLVTAYYTG -SKASGDQINALMADIGRLAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009C4C313 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. VMFN-G11Ma TaxID=2135609 RepID=A0A2T5BJM3_9ACTN -------PLRELERRHDARLGVFAHNLRTRRTV-AHRADERFPMLSTFKTLAAAAVLRDLD -RHGEVLARRIHYTRADLVDGAPITGKNLAHGMTVAELCDAAIRYSDNSAGNFLLRLLGGP -TAITRFARSLGDRVTRLDRWEPELNSAEPGRRSDTTSPRAIGGSYARLVLGSALNAPDRA -RLTHWLLTNTTGDHRIRAGLPDSWTVGDKTGSGSYGTTNDVAVAWTDDGDPVVVAVLSTR -PQQDAAWDDALQAEAAAIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00080F69D7 -----DDSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFALGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000C83C3EA ----TNKKFVQLEKKFDVRLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGNKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF58360 -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKEWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A5C4YKP3_BACCE -----DNSFAKLEKEYDARLGIYALDTGTNQTV-SYQSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cabrialesii TaxID=2487276 RepID=UPI0010117748 -----NHNFSKLEEEYDVKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTRGDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -AGFKKALEEMGDNVTNPERFEPDLNEVNPGETHDTSTAKALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2K8TT78_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVGTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -GEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001374ADC5 -----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHSNDRFAFASTSKSLATGALLHQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLRELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY1_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPEDHAPLVLVTYFTQ -PH--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7L210_BACCE --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYATRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Cronobacter sakazakii TaxID=28141 RepID=UPI000CFDD93D ------------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNSAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Stappia indica TaxID=538381 RepID=UPI0013033319 ---DIEGRLAALERKQGGRLGIAIHDVASGQTF-GNRADERFLMASTFKLMIAAFVLSRAD -REEEQLDRRIPFTTRDLVSWSPGTEKHAGGPLTVAELCEATMTMSDNTAANLLLKSFGGP -AALTAFARSLGDEITRHDRMEPELNADGPGDERDTTTPAAMAQTLRKLLFGDALSRRSRD -QLTAWLVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSSRGALIVTAYCEM -PQAEAKVRDATMAEIARIAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFC90CF ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0013D33ED5 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KSFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A168BD92_BACCE -----HDSFAKLEKKYNAKLGIYALDTGTNQTV-AYHSNDRFAFASTSKSLATGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLRELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8X1_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLPRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum So0157-2 TaxID=1254432 RepID=S4XWZ0_SORCE ----AAPALARIEAQVGGRLGVAALDTATGARI-GHRAAERFAMCSTFKTLLAACILARVD -QGQLRLDHRVTYRASDLLDHAPVTRAHLAQGLTVEELCAAVVEISDNTAANLLLAQIGGP -AGLTAYLRGLGDPVTRLDRNELALNENVPGDPRDTSTPDAMTDTVRAILVGDALQRASRE -RLASWMVRSTTGFARLRAGLPKDWVIGDKTGTGI-GIANDVAVAWPPSRAPIVIACFVDA -PSASADARNAAHADVARVVAEAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF9464B -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATNLQSFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD142 TaxID=718224 RepID=J7WUA1_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDRKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKLLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Caulobacter sp. 17J65-9 TaxID=2709382 RepID=A0A6B3UFS7_9CAUL ------PRIAEIEARVGGRLGVAALDLQNGRRF-AHRGDELFPMCSTFKFLLASQVLARVD -RGEERLDRRVPVAASDIVSWSPATKERVGAHMSVEELCAAAVSQSDNAAANLMLGFSGGP -QALTAFARSLGDEVTRLDRTEPGLNMGRPGDPRDTTSPRAMLKSMGAIVLGPTLTETSRG -RLTGWMKATTTGGRRLRAGLPSAWTIGDKTGTGERGTANDIAVAWPPSGGPVLITAYLTG -AEADAKARDQALADVGRVVGETw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKF6_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMGTLKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTMRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Mutant KPC family beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A6B7HYH4_ENTCL -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Prauserella endophytica TaxID=1592324 RepID=UPI0010BE4B6C ---TAEREFGELEQRFDARLGVYAVDTGTGREI-SHRADARFAYCSTFKALATAALLSERT ---IAELDEVVPYTVDDLVTFSPVTEKHAGAGLPLRELMDAAVRYSDNTAGNLLLRELGGP -KGLQAALREVGDQTTHVDRFEPELNEATPGDIRDTSTPRALATTLRAYALGDALTADKRA -ILIDMLRRNLTGDELVRAGVPDGWVVGDKTGTGGYGTRNDIAVVWPPDRAPIVIAIMSSR -AEQEAEPDNALLAEATKTVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia mexicana TaxID=279262 RepID=A0A370H285_9NOCA -------HFTDLEAKHDARLGVFAVDTGTGRTV-ATREGERFPMASTFKGLACGAVLQAHP -LSSGYFDQVIHYPATDLVEYSPETEKHVDTGMTVAELCDAAITQSDNTAGNQILKLIGGP -AGFTAFLRSLGDTTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDALPAPERE -RLTSWLLANTTGGKRIRAGLPADWKVGDKTGSPAYGGALDVAIVWPPDRAPLVIAVLTAK -SEQHAQADNELVAAATREAV--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=B7IXB0_BACC2 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKCK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium bangladeshense TaxID=1138189 RepID=UPI0007E538A9 --eNIERRLAALERRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDEKLDRRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -PGLTEWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASSTGKERLRAGLPQDWKVGDKTGTGPNGSLGDVAVIWPPDRGPIVAAVYIAE -ATAPVKDLNTIFAEVSKMITE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FC11_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSHVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=2 Tax=Cohaesibacter gelatinilyticus TaxID=372072 RepID=A0A285PBP1_9RHIZ --qELNRTISSWEKHLNARIGVLLSEMESDWSI-AHRADERFPMSSTFKSLLCGAVLARVD -ANEENLSNKITFTRKDLVSYSPVTKKRVKDGMSVSELCEATITISDNTAANLLLKRIDGP -KGLTKFLRKMGDTTTRLDRWETELNEGKPGDARDTTTPRAILGSLEKLAFGNVLKQKSSR -QLRQWMIDDKVADALIRAHLPKGWTIGDKTGAGGYGTRGIIAFIEKPDGKRYLAAIYMTE -NKADFPMRNKVISDIGRAMIT-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI0009ACEFA2 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTIADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=A0A1J0GZT9_VIRHA -----DEKFAEIEKEYNARLGVYAINTGTNQRV-QYNSDDRFAYASTFKVLAAAILLKQNS ---IEDLEKVVTFSKDDLVSYSPVTEKHVDTGMTLGEISEAAIRHSDNTAANLLLEEIGGP -KQFKQALRDLGDSVTQPMRFETELNEFTPGKKHDTSTPKAMAKTLKKVALDDFLPEDKRE -LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH -EEEDAEYDDALIAKAAEIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK418 TaxID=2512120 RepID=A0A4R3GR92_9RHIZ --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -RGDEKLDRRVTYGKEKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAEDSAN -QLVDWMVANTTGGGRLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVATVYMAE -TTVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia aggregata TaxID=187304 RepID=UPI000986F0EB ----LEKTVTSAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVRIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARV -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XBR4_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDVKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009950312 -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSSPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 166amftsu TaxID=1761753 RepID=A0A1H3QIR1_9BACI ---ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP ---IDKLNEVITYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP -EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALANDLKAFTVGNALPADKRK -ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYDNELIAQAATITIN-- ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A4R7RDF3_9BURK -----EAQLATLEQSSGGRLGVFALNTADGKQT-GYRADERFPFCSTFKVILIGAILARST -QVSGLLQQRIQYSQSDVVHYSAVTAQHVGDGMTVGELCVAAIQHSDNTAANLLIKLLGGP -QAVTAYARLTGNPVFRLDRMETSLNDAVPGDPRDTATPAAMARSLQTLTLGEALPVPQRT -QLLDWLRGNQMGSKRIGAALPAGWSMGDKTGTGDYGTANDLALIWPPSRPPILLAIYQTQ -REQDAKARDDVIAAAARIVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A370BA1 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKNSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0G8BZK7_9BACI ---AMYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Ensifer alkalisoli TaxID=1752398 RepID=A0A5P6NJW4_9RHIZ --dDVAKQLEELEKRTGGRLGVSVLDTRTNISF-GHRETERFAMCSTFKALAAACALARID -RGEEALDRRIAFGRDVLLPHSPVTGKHVGGNMTVAALCEAAITISDNAAANLLLESFGGP -AGLTSWLRSIGDEATRLDRMEPELNEAAFGDPRDTTTPAAMLETLRKLAFGSVLSESSRQ -RLVGWMVANKTGGARLRAGLPRDWRIGDKTGTSMAGAVSDIGFAWPDGRGPILVAVYTGE -AKAPLDALNPVFAEIGRIIA--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. T12-10 TaxID=2024610 RepID=A0A5A7W5T4_9BURK --kAIEAELASIERSVDGRLGVALLDMETGMRA-GHRVGERFPICSTFKQMLAANVLARVD -RGEENLERRIVFGQDRIDQYAPVTRERTGAPMTIAELCDAIVTMSDNTAANLLLDTVGGP -AGFTAFMRRLGDTVTRLDRNEPSLNEAIPGDPRDTTTPIAMLNDLREVLLGDALTAASRA -RLLAWGVGNRTGDTRLRVGVPGNWRVADKTGTGERGTTNDVGLLWPQDRQPIVVTVYLTQ -SPAPLRAREAAVADVARAIVR-- ->[subseq from] Ampicillin resistance protein n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00025EFB0D ----------------GARVGYIELDLNSGKVLeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVGELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLSGELLTLASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGEHGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASL---- ->[subseq from] Beta-lactamase n=1 Tax=Herminiimonas arsenicoxydans TaxID=204773 RepID=A4G2R9_HERAR ---AIQQEFSRLEASARGRLGLSAFNTGNGMRV-QYRAYERFPVCSTFKTIVAAAILQKST -TDKRLLNKRIRYNKDEVEQYAPITQKHIADGMSIAELCAATLQYSDNAAANFLMQELGGP -AAVTAYARTIGDDTFRLDRWEPELNTAIPGDLRDTSTPAAMGKSVQRLTLGDALALPQRE -QLVNWLKGNTTGGKRMQAGVPQDWIVGDKTGTGYYGTTNDAGVIWPATGAPIVAAIYFTQ -NEKEARPRDDIIASATRIVVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009ADB12E ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGGYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lactamdurans TaxID=1913 RepID=BLAC_AMYLA ---AVEQEFTRLQTQYDARLGLYAVDTGSGESV-AFRADERFAFASTFKALAAAAVLDSTT ---PQQLDQVVRYSKDELLENSPITKDHVATGMTLRELCDAAVRFSDNTAGNLLLKHVGGP -QGLDAALTAVGDEVTSADRWEPELNSAVPGDVRDTSTPRALAHDLRQFVLGDALAEDDRA -LLTDWLRRNTTGGTVIRAGVPADWVVGDKTGSGYYGGRNDIAVLWPPNRAPIVMAVMTSR -EEPRAKRADALLADAARVAVT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1B2VWF2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNXERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIA---------- ->[subseq from] UPI001411B27B UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001411B27B --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRTPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8D6P3_BACCE -----NHSFVKLEKEYDAKLGIYALNTGTNQTV-TYRSDERFAYASTHKALAVGALLQKNS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Class A beta-lactamase KPC-40 n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A4Y6E759_9ENTR -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGSANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodobiaceae bacterium TaxID=2026785 RepID=A0A2Z4UK77_9RHIZ ----ILETVRTVESRLGGRVGISIHDTGSGQRW-EHRSDERFPMSSTFKAFACAAVLSRIE -GGAERLHRVIEIEEEDLVTYSPVTETRVNTVMTIAELCEATITLSDNTAGNLILKSIGGP -KAFTDYMRSIGDETTRLDRWETDLNEGKPGDRRDTTTPRAATTSLGRLLLGPTLSESSRE -QLTTWMENDKVADALLRSVLPVGWRIADKTGAGGHGARSIIAVIWPPAESPILISIYMAE -SDASFAERNEAIAEIGAAIVT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A3S7Q8I3_9ENTR ----VQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPISEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA -QLVAWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKA------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0009B1E29E -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDPRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H5S5_9BURK ---STHRALQRIEAASGARLGVALLDTATGRRV-AHRADERFPMCSTFKFLAAALVLQRVG -RGLESLDRPVAIDAAKLVTYSPATGRQVGGHMTMGALCEAAVTLSDNTAANLMLESFGGP -AGLTRFARTLGDDVTRLDRFETALNEAIPGDPRDTTSPAAMLGLMRELLLGRALAPASRE -QLRGWMRGNTTGATSLKAGLPADWPIGDKTGAGGHGTRNDIAIVWPRDGAPVLVAAYLTG -AALDDAAQRRVLAEVGALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI000E31AFA5 ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNVLISEAAKAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00125F5478 -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHMDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYNDKLIADATKVVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8T0_9BACT ------------EDQLGARVGYIELDPNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011452F15 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8V5_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGSDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium frigidaeris TaxID=2038277 RepID=A0A2G8MF47_9RHIZ ---DAAARLAQLERRDGGMLGVEVRDTATGRRF-GHRADERFPLCSTFKAIAAAAVLARAD -TGEDDLSRRIAYGHDALLSYAPVTSKHVETGMTLAELCAAAVVWSDNTAANLMLDTIGGP -EGITAFARAHGDTVTRLDRTEPTLNTAIPGDVRDTTSPAAMVGLLDNVLLGRALSAESRA -RLVGWMHDSPTGLKRVRAGLPAGWRTADKTGTGDNGTANVVALIHRPDGAPILSAVYLTG -SPAEPAARDALHAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium bangladeshense TaxID=1138189 RepID=UPI0007E5B7E8 ---NIERRLAALERRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGDEKLDRRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLTEASSD -RLIAWLVASSTGKERLRAGLPQDWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVSKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE32C07 ---DIDKRLAALETRIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDEKLDRRVTYGKDKLVTYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP -AGLTDWLRSVGDGTTRLDRMETALNEATKGDPRDTTTPDAMLDTLGNIALGSILAEDSAN -QLVDWMVANTTGGARLRAGLPTGWKIGDKTGTGDNGSAGDIAIIWPPNRGPIVAAVYMAE -MTVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. WP9 TaxID=1500263 RepID=A0A1H5NEI0_9BURK ---AIRRRLAEIEAASGGRLGVSIVDTTSGLHA-GLRTDERFPMCSTFKVLAAGAVLARTD -RGAEDLQRRVVFSHSDVVPNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARGLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELLLGEHLSSSSRA -QLLAWLAANETGGARLRARLPKEWGVGDKTGTGDHGSANDIAILWPPGRGPVLVTVYLTE -TDGSAARSNAAIADVGALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium pisi TaxID=574561 RepID=A0A427MYG9_9RHIZ --dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-NYRGSEAFPMCSTFKALAVGFVLARVD -KGEENLQRRVSYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAANLLLESFGGP -PVLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASCD -RLIAWLVASTTGKERLRAGLPQDWKIGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIGE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000E1E90E6 ---ELRDEWARIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD -KGELTLAQRVKIRASDMLSHAPVTERHVGRSLSVGELCWATMIYSDNPAANLLFPLVGEP -AGLTAFLRGIGDTHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGDALQPASRE -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAAAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 344 TaxID=1566280 RepID=A0A1I0YXH3_9BURK ----AHTQLAALEQAAGGRLGVAAWRQGVEQRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMRVADLCAATLQYSDNSAANFLMKILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atroolivaceus TaxID=66869 RepID=UPI000690B3AF ---RTERAFAELERKYDARLGVYALDTGSGRTV-THRPDERFAYASTCKALLAGAVLDRNS ---LRELDRLVRYGRDDLVSHSPVTERHVATGMSLRELCDATVRYSDNAAANLLFRELGGP -RGLQDALRGLGDDVTRCDRYEVALSDAVPGDLRDTSTPRALADDLRAYVLGTTLPTDKRA -VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWPPDRAPIALAVLSRR -DTKDAERDDALLARAAEVTFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas phaseoli TaxID=1985254 RepID=UPI000536ACE3 ---MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00115589AB --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSKERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDPVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEARYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Alloactinosynnema album TaxID=504798 RepID=A0A1H0UTL2_9PSEU ---SAQRTLRELEAEYPGRIGVTAINTGTGKTI-RYRAHERFALCSTFKCLASAAILQEAR -ADPGLMERVIHYTHADLVTHSPVTELHVDTGMTVRALCAATMTTSDNTAANLLLRLLGGP -SSIGEFARTLGDRWTRLDRYETDLNTNLPGDPRDTSTPDAIARDLRKLVLGDALHPSDRA -ELTGWLIGNKTGDERIRAGLPKDWTTGDKTGGGDYGALNDIAVTWPPGGAPLVIAVYTTR -TDPTIPGQNRIVADIARVVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI000B5C8AA1 ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLARQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AR2-1 TaxID=2217816 RepID=UPI0011ED4D23 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTPEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A657Z4T2_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTPEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001155C32B --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPTRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000FFF01A4 -------PLRELERRHDARLGVFAHNLRTRRTV-AHRADERFPMLSTFKTLAAAAVLRDLD -RHGEVLARRIHYTRADLVDGAPITGKNLAHGMTVAELCDAAIRYSDNSAGNFLLRLLGGP -TAITRFARSLGDRVTRLDRWEPELNSAEPGRRSDTTSPRAIGGSYARLVLGSALNAPDRA -RLTHWLLTNTTGDHRIRAGLPASWTVGDKTGSGSYGSTNDVAVAWTDDGDPVVVAVLSTR -PQQDAAWDDALQAEAAAIVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T9G2_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAATLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDVRNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Soil768D1 TaxID=1736405 RepID=A0A0Q9VIG4_9BACI -----NHDFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWXVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DKKDADYNDKLIAEATEEVIK-- ->[subseq from] OFF7_DB04V3 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEF8E -----------VAARLKARVGYIELDLNSGKILeSVRSEERFPMMSTFKVLLAGAILSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP -KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG -SQATMDILNEAIAMLGRAMIEKw ->[subseq from] class A beta-lactamase n=1 Tax=Numidum massiliense TaxID=1522315 RepID=UPI0006D5B046 -------DFAKLEEQFDARLGVFALDTGTNQTV-TYRADERFAHVSTHKALTVGVLLQKKS ---IEDLNQTITYTRDDLVDYNPITEKHLDTGMTLKELCDASIRYSDNTAHNLILKELGGP -KGLKKSLREIGDEITNPERFEPELNEVNPGETRDTSTPRALATSLQAFTIGDVLPTEKRA -LLTDWLKRNTTGDTLIRAGVPKGWKVADKTGAGFYGTRNDIAIIWPPDKDPIVLAVLSSR -DKKDADYNDKLIAQATKKVID-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A2T8L6_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -LLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAAL---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8YMA8_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. higo TaxID=132266 RepID=A0A243KGJ8_BACUH ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKITLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas wittichii TaxID=160791 RepID=UPI00055B36D8 ---DISKQLGDLERQSGGRLGVAMLDCGNGRLI-GWRLDDRFPMCSTFKMMLAAFILHRVA -IGEERLDRRIVVGTADLLSYAPVTGKHVGDPMTIEALCEAAVAMSDNTAANVLLATAGGP -MAFTRFARSIGDRETRLDRIEPALNEARAGDPRDTTTPAAMARSLRKIALGSALPADGRT -LLTRWLIGCRTGAARLRAGLPAGWAVGDKTGTGERGSTNDIAIIWPTGRDPVIVAAYMTG -GTLGADAREAILASVGRLAAGYf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3CB6C -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID13726 TaxID=2706058 RepID=A0A6B2XAB9_9ACTN ---DVPARLRALEKDHDARLGVYAHNLATGRSV-AHRADELFPICSVFKTLTAAAVLRDLD -RDGEELARRIHYTRADLVDGAPVTGKNLAHGMTVAELCDAAIRYSDNSAANFLLRELGGP -TAITRFARSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGRSYGRLVLGDALNRRDRA -RLTDWLLRNTTGDRRVRAGVPVGWTVGDKTGSGSYGTTNDVAVAWTPEGAPIVLAVLSTT -PQADRAWDDALVAGAASVAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AEC803 ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWL9_9BACT ---DAEARLAELERAHGGRLGVAVLDLANGRRI-GHRADERFLMLSTFKTLAAALVLARVD -RGEERLDRRIVFSESDLVVWSPVTENRVGRAMTLAELCEATITLSDNTAGNLLLDSFGGP -AALTDYLRSLGDEVTRLDRIEPDLNEDAPGDLRDTTTPAAMLETLHKLLFGDALSRHSRD -QLNAWLTINKTGDQRLRAGFPENWLVGEKTGTNRSGTANDAGVAWPIDRGPILVAAYCEM -SSISPEKRNAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus TaxID=1386 RepID=A0A2B1CB74_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKATATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] D12_DB04V3 n=1 Tax=synthetic construct TaxID=32630 RepID=UPI00077DEFCA -----------VAARLKARVGYIELDLNSGKILeSVRSEERFPMMSTFKVLLAGAILSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELASAAITMSDNTAANLLLTTIGGP -KGLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPVAMATTLRKLLTGELLTPASRQ -QLMDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIVAALGPDGKPSRIVVIYTTG -SQATMDILNEAIAMLGRAMIEKw ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI000EF445C1 -----DEKFAEIEKEFNARLGVYAIDTGTNQRL-QYNPDDRFAYASTFKVLASAILLKQNS ---IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP -EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE -LLHNWMKGNATGDKLIRAGAPEEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH -EEEDAEYDDALIAKAAEITL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFC9D90 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus firmus TaxID=1399 RepID=A0A0J5W1J3_BACFI ---NTNQKFKQLEKEFDARLGVYAYDTGTKKTI-AYRSNERFAYASTFKPLAAAILLKRKS ---LEEMDEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRHSDNTAGNLILEELGGP -DGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPKALAASLQKVLMGDFLPEEKRN -VLTDWMRGNVTGDPLIRAGVPSGWEVADKSGAAGYGTRNDIAIVWPPNREPIIMTILSSR -DSKDAEYDNSLIAKTAEMTIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000C161908 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKV----- ->[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora azurea SZMC 14600 TaxID=1114959 RepID=H0K2N4_9PSEU ----VQGELRALEARHAARLGVYGINTRSGAVV-SYRAHERFPMCSTFKTLAAAAVLRDLD -RDGEVLDSWVHYTEDDLVVGSPVTERHVGTGMRVADLCAAAVSESDNTAANLLLDRIGGP -RGVTRFCRSLGDRLTRLDRYEPDLNSALPGDLRDTTTPAAIAEDYRRLVVGTALDRGDRA -RLTTWLTESVTSDTRFRAGLPSHWRVADKTGSGSYGTANDVGVAWTDDGTPLVLAVLSTK -HTPDAEWDDALVAGTARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000A19DFD8 -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQQKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Prauserella coralliicola TaxID=1401264 RepID=UPI000D830348 ---TAEREFGELEQRFDARLGVYAVDTGTGREI-SHRADARFAYCSTFKALATAALLSERT ---IAELDEVVPYTVDDLVTFSPVTEKHAGPGLPLRELMDAAVRYSDNTAGNLLLRELGGP -KGLQAALREVGDHTTHVDRFEPELNEATPGDIRDTSTPRALATTLRAYALGDALTADKRA -ILIDMLRRNLTGDELVRAGVPDGWVVGDKTGTGGYGTRNDIAVVWPPDRAPIVIAIMSSR -AEQEAEPDNALLAEATKTVVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B2A106 --qATYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02058 TaxID=1703921 RepID=UPI00093C69F5 ----TKASFDELEQKFDARLGVYAIDTGSGLSV-THRPDERFAYASTCKALLAGAVLDAVT ---VARLDRRVRYGRDELVANSPVTGKHVDAGMTLRELCDAAIRHSDNTAANLLFHELGGP -RGLQDALRGLGDRTTRCDRYETELSEAAPGDPRDTSTPRALAAGLRAYALGNVLGAKERA -LLTDWLRRNTTGDDVIRAGTPDGWVVGDKTGTGGYGTRNDIAVLWPPDSEPVVLAVLTRR -ETRDAVHQDALIAEAARVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000E1F3D95 ---ELREEWARIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD -KGELTLAHRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLIGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAAAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS80.1 TaxID=1680159 RepID=A0A1Q5RNH8_9BRAD ------EAITQLELKSGGRLGVSVLDTRTGAQI-HHKGNERFPMCSTFKVLASAAILKNAG -SKLDSLERRVRIEQADIVENSPVTLEHVGGEMSLLEVCDAAITRSDNTAGNLLLKNIGGT -AGLTSFARSIGDKVTRLDRTEPELNEATPGDPRDTTTPNAMTASFSGLLLGRVLLPEARD -QLAKWLIANKTGDTRLRAGLPQSWRVGDKTGAGEHGTTNDVAIVWPPEHPPLIIGVYLTG -AALDPNGRNDVIASVGREISKSf ->[subseq from] Beta-lactamase class A n=1 Tax=Paenibacillus sp. cl141a TaxID=1761877 RepID=A0A1H7QMD1_9BACL ------------AAEDGIELSVGIQDLSGGGKI-QVGSSDVYYAASTIKIAIVTALMQDIE -AGKYALEQTIQVQPEQVVGGAGSLKDKFPLDITIESLARLMITQSDNTATNALIDLL-GF -ERINAFIEEQGFETMQLGRKMMTPAKS--PAADNYVDGEELLTLLERIYAGEILTAKSRD -QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-AAVTVLTKV -TKKAQELGNPVVQRVAKAVYN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Paenibacillus sp. cl141a TaxID=1761877 RepID=A0A1H7QMD1_9BACL -------------EDKGIRVSVGLKDLSGDREL-LLGSRQSYMPASTIKMALVSGLMKEVD -AGKLTLEETVKVEKEDVVGGTGSLQKETPQDVTIERLAKLMITQSDNTATNVLIDVV-GL -DEVQNLMDELGLDVMHLGRKMFAAA--PTPEQDNYIDAEDLVHLLAYIHSGSFLSDNSRD -QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGRE-IAISVLTEV -TTEAQAIGNPVVQEIAKAVYE-- ->[subseq from] Beta-lactamase n=1 Tax=Methylarcula marina TaxID=72022 RepID=A0A422QXU4_9RHOB ---AVTDRVIEAEQKLRARVGYSMLDLTSGETA-GYRSDERFPMLSTFKVPLCAAVLARVD -AGEEDLDRRITYSSADLVEYSPVTEQHVESGMTLSDLCEAAITMSDNTAANLLLESVGGP -EGLTAFLRATGDGISRLDRWETELNEALPDDPRDTTTPQAMVATLDRLLFGGILSESARK -TLVTWMENNLVADDLIRASLPQGWYIADKSGAGARGSRAITGVLGPEGRPERIVAIYMTE -TPASIETRNAEIAAIAKVIVADw ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. WMMA1423 TaxID=2591108 RepID=UPI00114625DE ---KVTRQIGRLEATHHARIGAFAIDTGTGRTV-SHRPDERFAFASTFKAMACGAVLRKAR -QDPGLLDRVIHYTEDDLVDYSPVTEKHVDTGMTVADLCHAAITQSDNTAGNLVLRQIGGP -AGLTAFFRSLGDRVSRSDRWETDLNIWAPGEVRDTTAPRPWAGDLRALTTGGALVPADRK -RLVDWMKATVTGDKRIRAGLPKNWTVGDKTGTGGYGTANDIAIAWPPSGAPLVIVITTNG -LSADAEADDKAVAQTARILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF4C2EF -----NDSFAKLEKEYDAKLGIYALDTGTNQTF-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDEKITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTALNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C5GQ78_9BACI -hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Micromonospora sp. KC213 TaxID=2530378 RepID=A0A4R4Q158_9ACTN ----------ALEQRFDATLGVYAIDTGTGRTL-AHRPDERFAYASTVKALAAGALLDVTS ---DAELDRVVRYRRADLVTYSPITEQHVDSGMTLRAVADAAVRYSDNTAANLIFAELGGP -DGFERRLREIGDTVTEPARIETALNEAAPGDVRDTSTPRAMATSLRAYALGDALSDADRA -VLVDWLRRNTTGAKLIRAGVPADWQVGDKTGSGGYGTRNDIAVLWPPQGAPIVLAVLSRR -DTKDAGYDDALIAEAARLVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_331 TaxID=1969379 RepID=A0A328MBV8_9BACI ------DSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDAHDTSTPKALATSLQAFALGDILLTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=UPI0013DA0B9B ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GNREEERFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLINWLVGNTTGNNRLRAGLPTEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATASAKDVEAVFAEVGKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. B05 TaxID=1945859 RepID=A0A1V3PR98_9GAMM -----EARLAALQRRHGGRLGVAVLDTGTGRRV-AQRGDERFLLCSTFKVLAVAAVLARVD -AGGEKLDRRIVFGRDVLLDYAPVTRQQVGAPMTVAGLCAAAITLSDNTAANLLLASLGGP -AAVTRFVRSLGDPVTRLDRIEPELNEGGPGEIRDTTTPNAMLDTLQRLLLGHVLTEASRT -RLIGWLRACTTGTDKLRAGIPADWQAGDKTGSGAHGESNDVAIFWPPHRKPILVTAYYAG -SSADGQQRGAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root483D2 TaxID=1736545 RepID=A0A0Q7NCQ8_9RHIZ --kDIEKQLAALEKQTGGRLGVYVLDTKTKASF-SHRPDERFAMCSTFKALAAACVLARAD -KGEEKLDRKVLITKKHLLTYSPAVEKRVGGAMTVRELCDAAVTLSDNGAANLLLASFGGP -KGLTDWLRTIGDATTRLDRWEPELNEAKIGDPRDTTTPKAMTETLGKLLLGDTLSTASRD -QFTAWLIANTTGAKRLRAGLPKTWTIGEKTGTSGHGEAGDIGFVRPSGDHTILVSVYIAE -GKKPTKELEPVFGDVGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Haematospirillum jordaniae TaxID=1549855 RepID=A0A143DG37_9PROT ----AVQRLSDLESTFDGRLGVFAFDTSSGAAL-AWRSEERFPLCSTFKAFLAAAILHRST -SDIGLLDRVISYPLEELVFHSPVAQQHVHSGMSVRDMCAAAIQYSDNTAANLLMRILGGP -DAVTAFMRQTGDMDFRLDRWETDLNTAIPGDLRDTSTPVAMARSLDHLLFGDVLSDTHRA -LLQDWLKGNTTGASRIRAGVPDGWMVGDKTGSGSYGTANAIGVLWPPGRKPVIVSVYTTQ -HYRGAVWRNDIVAQATRIIVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora fusca TaxID=1997 RepID=UPI0008316487 -------RFAALERRHGARLGVYALDTGTGITV-AYRADERFAFCSTFKALAAAAVLHRNP ---LSHLDTRVTYTEADVNSISPITRNHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -RKLTAYLRELGDTVSRMDNYEPELNSDRPKDPRDTTTPRAIASDYQKLVLGDALTPDKRA -LLKDWLVRNTTGGERIRAGLPKGWKVADKTGTGNYGRVNDIAVVWPPHAASLVLAVMSDR -RGFNAPQESALIAEAARQAV--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B3KNB9_BACTU ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKITLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0008727F4A -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEAHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2C2AN01_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPKLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00053502D5 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2FBI8_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=UPI000A3736DE -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDGRITYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGVTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALILGDALPAAGRA -LLTDWLVRNKTGDRRIRAGAPRGWKVGDKTGSGDWGRCNDVAVLWPGGGPPLMLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00125EDB68 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Sinorhizobium americanum TaxID=194963 RepID=A0A1L3LJV3_9RHIZ ---DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGDMTVAELCDAAVTISDNAAANLLLESFGGP -AGLTSWLRSIGDRTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR -QLVEWMVANTTGDARLRAGLPKEWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE -AKVEPAELNPVFAEVGKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A109G0V0_BACMY ------HSFVKLEKEYDAKIGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD4FA22 --dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLAAGMVLARVD -GGDENLERRVTYDQDKLVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLDSLGGP -EALTKWLRSIGDTLSRLDRIETELNEAKKDDPRDTTTPDAMLDTLGNLALGTVLSEPSRQ -QLIDWMIANTTGAARLRTGLPEEWKVGDKTGTGSNGSAADIAIIWPEESSPILVAVYVAE -ATAPVSELNDVFAEVAKLAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ISID311 TaxID=2601673 RepID=A0A5C6WBN8_9ACTN ---DAHAALRRLERAHRARVGAYAHNTATGTTI-AYRADTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRVHYTAADVVANSPVTGKHLATGMTIAELCAAALQRSDNTAANLLLRTLGGP -TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIARTYTRLLLGDALTPADRA -RLTAWMKANETNTDRFRAALPRDWTLADKTGTGSYGTGNDVGVAWTPDGTPLVLAVLTGT -AQQAAPSDDPLVADVTRVIAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 4F TaxID=1751294 RepID=UPI00073A9AF6 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERISYGAADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA -LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRANDVAVLWPGGGSPLVLSVLTDR -PDRAAPGQDELVAEATRRVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=C2UE15_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEASVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A9A0N8_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYENALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFMVGDALPAQKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011559997 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDIVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -LLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI000996316A ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLATYLNG -AKVDDAARDTALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI0012E0C15A ----TNKKFVQLEKKFDAKLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALISEAAKAALD-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI00039AE61E --tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SMI5_9BACT ---EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -IGLTNFARTIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH -QLEQWLQANQTGASMIRAGVPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG -STATANDRAAAIVEAARVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9ZFM8_BACMY -----NQSFVKLEKNYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -VKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0011460A66 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5AKN3_9BACI -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEAQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. RZ2MS9 TaxID=1806216 RepID=A0A1G1UFZ5_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIVTNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2T0EC12_9BACI -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=A0A221BSW3_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF515C3 -----NQALAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9PJG7_BACCE -----NQALAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium sp. C-61 TaxID=238241 RepID=UPI0009FD351E -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -EKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDASFRLDRREPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALGAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1X6PRF9_BACMY --nTVNQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYNDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella quasipneumoniae subsp. similipneumoniae TaxID=1463164 RepID=A0A455MD31_9ENTR ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNTAGNLLLKIVSGP -AGLTAFLRQFGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TPATMVERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFE020F -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF07720 -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. AY3-1 TaxID=2217817 RepID=UPI0011EC1A92 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVQKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPQNRAPIIIAILSSK -DEKEATYDNQLVAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKE2_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERGTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLCSALPAGWLIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02058 TaxID=1703921 RepID=A0A1Q5CZ52_9ACTN ----TKASFDELEQKFDARLGVYAIDTGSGLSV-THRPDERFAYASTCKALLAGAVLDAVT ---VARLDRRVRYGRDELVANSPVTGKHVDAGMTLRELCDAAIRHSDNTAANLLFHELGGP -RGLQDALRGLGDRTTRCDRYETELSEAAPGDPRDTSTPRALAAGLRAYALGNVLGAKERA -LLTDWLRRNTTGDDVIRAGTPDGWVVGDKTGTGGYGTRNDIAVLWPPDSEPVVLAVLTRR -ETRDAVHQDALIAEAARVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI0007E98722 ---NIEHRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAVGFVLARVD -KGQESLERRVTYGRDKLVDYSPLSEKHADTDMTIAELCEAAVTVSDNTASNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSVLAEPSSE -RLIAWLVASTTGKERLRAGLPQDWKVGDKTGTGQNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPIFAEVGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9ZAJ9_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8EA8F ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMNRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=J8D454_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTIADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -VLTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAAYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 13 TaxID=2035211 RepID=A0A2G6RM14_9BURK ---AAQTQLAALEQAAGGRLGVAAWRHGSEQRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMKILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR -EQKKADTNQDIITAATRIVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=UPI000B9D4FC6 ---EVKHHFAKLEDQFDARLGVFALDTGTNQTV-TYRPDERFAFASTLKALAVGALLQQKS ---IKDLDQNITYTHDDLVSYSPITEKHVNTGMTLKELSDAALRYSDNTAMNLILQQLNGP -KGLKKALRKIGDHVTNPTRFETELNDVQPGETRDTSTPRALATSLQAFTLGDALPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWEVADKTGAASYGTRNDIAIIFPPNGCPIVLAILSSR -DKKDAEYNDELIAGATKEVINEf ->[subseq from] class A beta-lactamase n=1 Tax=Proteus hauseri TaxID=183417 RepID=UPI0007E7F1F3 ---AIEQQLAALEKSTQGRLGVALINTADNSQI-TYRGNERFAMASTSKVMAVAALLKESE -QKTDLLDKNISIKQSDLVAYSPIVEKHLTTGMTLAQLSAATLQYSDNTAMNKILAHLGGP -EKVTQFARSINDITYRLDRSEPELNTAIHGDPRDTTSPLAMAKSLQALTLGDALGQYQRN -QLITWLKGNTTGDNSIKAGIPKQWIVGDKTGSGDYGTTNDIAVIWRENQAPLILVIYFTQ -QEQNAKPRKDIIVKATEIVTKPf ->[subseq from] Beta-lactamase n=3 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TX89_9BACT ---EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -IGLTNFARTIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH -QLEQWLQANETGASMIRAGVPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG -STATANDRAAVLAEAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VDM053 TaxID=1053249 RepID=R8P7B2_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011507F0C --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALATGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A433MIG0_9BURK ---SAEARLAALESAAGGRLGVVGFNTGSGARI-QHRAHERFPLCSTFKLMLAAAVLERSA -KDASLLPRNVSYGKGDLIDHSPITEKHVATGMTVAGMCAATIQYSDNAAANLLLKVLGGP -SAVTAFARGIGDQAFRLDRTEPELNTSIPGDPRDTTTPAAMSDSIQRLVLGDALGAGQRD -QLRTWLLGNTTSTERFLAGVPAGWKVGDKTGAGSYGSTNDVGVLWPPTGAPIVLSVYLTF -PQKDAGNRNDVVASATRIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FA98_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00080DFD69 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AAVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTMPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. K2I17 TaxID=2014743 RepID=A0A246PHB4_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTYDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGEWEIADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DIEDAKYDDKLITEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF98157 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS ---MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000B432E83 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000871B9AF ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS ---MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B70C95F --qATHKEFSQLEKKFDTRVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8K6Q1_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGGYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF01BE0 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. C1B10 TaxID=1397530 RepID=U7GN62_9RHOB ----LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVKIRSQDLVSYSPVTEKKIGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGNALSSTARA -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C5PQ40_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=A0A1R1RM60_9BACI ---EVKHHFAKLEDQFDARLGVFALDTGTNQTV-TYRPDERFAFASTLKALAVGALLQQKS ---IKDLDQNITYTHDDLVSYSPITEKHVNTGMTLKELSDAALRYSDNTAMNLILQQLNGP -KGLKKALRKIGDHVTNPTRFETELNDVQPGETRDTSTPRALATSLQAFTLGDALPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWEVADKTGAASYGTRNDIAIIFPPNGCPIVLAILSSR -DKKDAEYNDELIAGATKEVINEf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000826CBDA -----NQKFVQLEKKFDVRLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNDVIRYSKEDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDIRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSFGTRNDIAIVWPPDRAPIVLAILSKR -FTKDANYDNALIAEAAKVAFD-- ->[subseq from] Carbapenemase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0001BE63E6 -------PFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCXSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPSDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEF9C03 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPEVNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3873 TaxID=1854056 RepID=A0A1A5RH95_9RHIZ ----ATKAVEALEARNGGRLGVMILDVGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD -DGKAKLDDRIVYAASDVEPYSPITKDHVGDGMKLEDVCAAAVVWSDNTAGNLLLRVLGGP -QGLTRFARSLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK -RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG -STAPRASREAVHRDMARIIVETf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=L7QJP2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSSVSEKHLAGGMTVGELCAAAMTMSDNRAANLLLATVGGP -AGLIAFLSQIGDNVTRLDRWETEVNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF231B2 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEELVDYSPVTEKHIDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPLHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar argentinensis TaxID=180880 RepID=A0A243K6J9_BACTU ------DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREIGDTVTTSERFEPELNEVHPGETHDTSTPKAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A5C4NVA1_9BURK ---TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. HH104 TaxID=1537276 RepID=UPI0008739D4F ---TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD86566 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQTS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0G8EQ42_BACCE --qATYKDFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Class A beta-lactamase n=2 Tax=Xanthomonas TaxID=338 RepID=A0A643E0Y0_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F472DF6 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDER--------------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEE5605 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000CD8B1EA -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000B445703 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus TaxID=1396 RepID=R8I5E4_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD1A45 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7XC64_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -QGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0013D4B9DB ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7II52_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0HRP0_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCD1_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSAGSPR -HLLQWMVNNRVAGPLIRSVLPAGWFIAEKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Haematospirillum jordaniae TaxID=1549855 RepID=UPI00143311E3 ----AVQRLSDLESTFDGRLGVFAFDTSSGAAL-AWRSEERFPLCSTFKAFLAAAILHRST -SDIGLLDRVISYPLEELVFHSPVAQQHVHSGMSVRDMCAAAIQYSDNTAANLLMRILGGP -DAVTAFMRQTGDMDFRLDRWETDLNTAIPGDLRDTSTPVAMARSLDRLLFGDVLSDTHRA -LLQDWLKGNATGASRIRAGVPDGWMVGDKTGSGSYGTANAIGVLWPPGRKPVIVSVYTTQ -HYRGAVWRNDIVAQATRIIVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. CD3-1a TaxID=2587158 RepID=UPI0011240B7A --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGEIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A2S6Y5K6_9XANT ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00065B4CA1 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -TEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. LK7 TaxID=1628209 RepID=UPI0012E01217 -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRTDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5IBW9_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Class A beta-lactamase n=9 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A6B3KGF0_XANEU ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADDDPRDTTTPAAMAATLRTLLLGDALHPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4YYV4_9BACI ------DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKG1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILgSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHCSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLTSRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. BJB312 TaxID=1560197 RepID=A0A2G3M1W1_9BURK ---AAQTQLAALEKSAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMTVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLLAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Stappia indica TaxID=538381 RepID=UPI0009F3FBFB ---DIEGRLAALEREQGGRLGIAIHDVASGQTF-GNRLDERFLMASTFKLMLAAFVLARVD -REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTMSDNTAANLLLASFGGP -AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPAAMAETLRKLLFGDALSRRSRD -RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSGRGALIVIAYCEM -PKAEAKTRDATIAEIARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus amyloliquefaciens TaxID=1390 RepID=UPI000C78370A -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVGYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDASYNNALIAETAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8NA09_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKALAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0008651ECA -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRYETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI0009960FA7 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A1C4XQ95_MICEC ----ADRSFDALEARFAARLGVFAIDTGSGATV-THRADERFAYASTFKALIAAALLDATT ---PAQLDRVVRYTRADLLAHAPVTREHVGTGMSLRDLADAAVRYSDNTAANLILAELGGP -AGLARHLRALGDRTTKPVRTEPALNEATPGDERDTSTPRALATDLRAYVLGDALDAGDRA -LLTDWLRRNTTGDALIRAGVPAGWTVGDKTGTAAYGTRNDIAVLWPPEGAPIVLAVLSSR -AAEDAEHDDALIAEATRVTLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=A0A657RHD5_9BACI -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYTKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bordetella genomosp. 1 TaxID=1395607 RepID=A0A261SHX0_9BORD ---DLPRQLARLEARDGGRLGIAVLDTGSPFTL-AYRADERFPLCSTFKWLAAAAVQARVQ -QGQDLPERRIRYGAPDMVAYSPVTQQHLTDGMTLDALCEAAVVWSDNTAGNLLLSTIGGP -PGITAFARAMGDDLTRLDRIEPALNEARPGDERDTTTPLAMQRLLQKVVLGDGLAPAQRE -RVQAWMRGCRTGDTRLRAGVPGDWVVANKTGAGGNGTNNDVGVLWPQRGAPVVVAAYLTG -SPASREAQNALLAEAARLIA--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Pectobacterium brasiliense TaxID=180957 RepID=UPI00057CC6E0 --pDTLDTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFDQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP -QELTIFLRKTGDHVTRLDRWETALNEALPGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -SQATIEERNKQIAEIGTSLIKHw ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011AB452C --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=UPI0009A2B316 -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYNNALIAEAAKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDEBBCC --kDIEKQLTALEKQTGGRLGVYVLDTKTKASF-AHRQDERFAMCSTFKALAAAFVLARVD -KGEEKLDRRISISKKHLLSYSPVVEKQVGGGMTVGELCDATVTYSDNAAANLLLASFGGP -KGLTDWLRSIGDGTTRLDRIEPELNEAKIGDPRDTTTPMAMTQTLGKLLLEDVLSPASRD -QFSAWLVANTTGDRRLRAGLPKGWTIGEKTGTSGHGEAGDIGFMRPAEGHTVLASVYIAE -GKKPTKDLEPVFGEVGKLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG3X2-1 TaxID=1053183 RepID=J7XPQ3_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWA1_9BACT ---DAEARLAELERAHGGRLGVAVLDLANGRRI-GHRADERFLMLSTFKTLAAALVLARVD -RGEERLDRRIVFSESDLVVWSPVTENRVGRAMTLAELCEATITLSDNTAGNLLLDSFGGP -AALTDYLRSLGDEVTRLDRIEPDLNEDAPGDLRDTTTPAAMLETLHKLLFGDALSRHSRD -QLNAWLIINKTGDQRLRAGFPENWLVGEKTGTNRSGTANDAGVAWPIDRGPILVAAYCEM -SSISPEKRNAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. B1-WWTP-T-0.5-Post-4 TaxID=2653219 RepID=UPI00126257E0 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia aromaticivorans TaxID=2026199 RepID=A0A248VRZ3_9BURK ----IRRRLAEIEVASGGRLGVSIVDTMSGLHA-GWRTDERFPMCSTFKVLAVGAVLARTD -RGEEDLQRRVVFSQNDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARGLGDGITRLDRNEPTLNEAMPGDPRDTTTPNAMLGNLRELLLGEHLSPPSRA -QLLAWLAANETGGARIRARLPKEWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGNAARSNAAIANVGALVVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001145D60D --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKATATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011A4D009 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LETLDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus indicus TaxID=246786 RepID=A0A084GIY5_BACID -----NHDFAELEEKFDAKLGVFALDTGTNQTV-TYNPDERFAYASTHKALAVGALLQQIS ---IEDLNQRITYTREDLVNYNPVTEKYIDKGMTLRELADASLRYSDNTAGNLILNQLGGP -AGFKKALEAIGDDITSPERMEPDLNEVNPGETHDTSTPRALAASLQDFILGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGSGSYGTRNDIAIIWPSKGDPIVLAVLSSR -EKKDADYDDKLIAEATEMVMN-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca TaxID=47850 RepID=A0A3M9KNC6_9ACTN -------ELAALERRSGARIGVYALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARAAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0D7S2_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -DKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDASFRLDRLEPELNSAVPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCF4_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP -QLLQWMVDDRVAGPLIRSVLPAGWFIADKNGTGKRCARAIVALLGPNNKAKRIVVIYLRD -TPANMAERNQQIAGIGAALI--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. mangiferaeindicae LMG 941 TaxID=1156940 RepID=H8FK52_XANCI ---MLRAQWAQIERGAGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. higo TaxID=132266 RepID=A0A243KBM6_BACUH --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Schlegelella thermodepolymerans TaxID=215580 RepID=A0A2S5T2H5_9BURK ---------LAIENESRGRLGVAVLDTATGVLQ-GHRLDERFPMCSTFKWVLGAHVLHRVD -QGLERLDRRIVYGPEALVPWSPVTERHVGTGMTVGQLCEATITLSDNAAANLLLATLGGP -QGLTRYIRSQGDTVTRLDRTEPQLNEARPGDPRDTTSPRAMAQLLRTVVLGEGLSRSGRA -QLVRWLQDCKTNGQRLGAHVPAGWALGSKTGSGARGATNDVGIYWPADRPPVVVAAYLAE -TQASDAARNAALARVAQQVTRAy ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase CRH-2 n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2R2V0K7_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -EKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDASFRLDRLEPELNSAVPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium polaris TaxID=2042057 RepID=UPI000D60E570 --pDTLDTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP -QELTIFLRKTGDHVTRLDRWETALNEALPGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -SQATIEERNKQIAEIGTSLIKHw ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0013EF3CE9 --tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-AYQPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPALNEVNPGETQDTSTARALATSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru62 TaxID=2080745 RepID=A0A2S4ZL22_9ACTN ---AVHAELAELEQRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFHRSLGDEVSRLDRWEPELNTAIPGDPRDTTTPEAIAASLERVTLGRALSRADRE -RFVGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTSRRTPLVLAVLSGK -DTPDAPVDEALIADAAAVVAR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_54_12 TaxID=1805419 RepID=A0A1Q6VQM8_9BACT ---DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD -EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -SGLTNFVRSLGDRLTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDALSEASRR -QLEDWLQRNETGGPMIRAGVPKNWILGDKTGRGSNGATNDIAIMRPPDRAPILLAIYSVG -STATPTDRAAAVAEVAESFV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7VWB3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLHKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0014447161 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDNRFAFASTSKSLAVGALLRKNS ---LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus (strain G9842) TaxID=405531 RepID=B7INI5_BACC2 -----NDSFAKLEKEFDAKLGIYALDTDTNQIV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A0K0QLK7_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. K4S16 TaxID=1316147 RepID=UPI0011EED064 ---RVTRQIGRLEATHHARIGAFAIDTGTGRAV-AHRPDERFPFASTFKAMACGAVLRKAR -QDPGLLDRVIHYTKDDLVEYSPVTEKHVDTGMTVADLCHAAITQSDNTAGNLVLKQIGGP -AGLTAFFRSLGDTVSRSDRWETDLNIWKPGEVRDTTAPRPWAGNLRALTTGGALVPADRE -RLVDWMKATVTGDKRIRAGLPNNWTVGDKTGTGGYGTANDIAIAWPPSGAPLVIVITTNR -FAPDAAADDQAVAQTARVLAN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00115574C5 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY7_KLEOX ---AIQQKLTNLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTXKVMAAAAVLKQSE -SHPDVLNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C2I8U2_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00065BE107 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBCB63 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGILLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF21882 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B3KGW4_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=R8HW30_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF72B1A -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=Q9L6I3_SERMA ---ELDSALARLEQQHHGRLGLAYIDSGSGESY-SYRGEERFAFCSTFKAVLAGAVLQRSV -SQPGLLDKRVHYAATDLLAYAPITKTHLDKGMRIGELAAAAVQYSDNTAANLLLQEIGGV -QALNRFVQGLGDPAFRLDRIEPHLNSAEPGDVRDTTTPLAMAHTLQAMTLGKGLPQAQQA -QLVSWLKGNTTGAQRIQAGVPAGWQVGDKTGTGGYGTTNDIAILWPEQGAPKVLAIYFTQ -PAADAEANRAILAEATRLVLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9PYX7_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS ---MEDLNQRILYTREDLVNYNPITEKYVNKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLKDWMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFE1B40 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A2A7H589_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8HVM0_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00084C5DD1 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAITKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=9 Tax=Bacillus TaxID=1386 RepID=A0A2C3MI64_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J7W2D0_BACCE ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPTNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI00056B94B5 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP -AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGCFADIAVVWPPDRGPILVTTFVAE -GTAPAKDIEAVFADVGKIVT--- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A2A5LJM2_PAELA ------------AAEDGIELSVGIQDLSGGGKI-QVGSSDVYYAASTIKIAIVTALMQDIE -AGKYALEQTIQVQPEQVVGGAGSLKDKFPLDITIESLARLMITQSDNTATNALIDLL-GF -ERINAFIEEQGFETMQLGRKMMTPAKS--PAADNYVDGEELLTLLERIYAGEILTAKSRD -QILAWMKAQEV-KTKFGAALP-GKPIAHKTGELGD-VSHDIGYFLVPGRE-AAVTVLTKV -TKKAQELGNPVVQRAAKAVYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus lautus TaxID=1401 RepID=A0A2A5LJM2_PAELA -------------EDKGIRVSVGLKDLSGDREL-LLGSRQSYMPASTIKMALVSGLMKEVD -AGKLTLEETVKVEKEDVVGGTGSLQKETPQDVTIERLARLMITQSDNTATNVLIDVV-GL -DEVQNLMDELGLDVMHLGRKMFAAA--PTPEQDNYIDAEDLVHLLAYIHSGSFLSDNSRD -QIIDWMKAQEV-DTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGRE-IAISVLTEV -TTEAQAIGNPVVQEIAKAVYE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7863E -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A27CE72 -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A7ZLU9_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRITMSDRFETELNEAIPGDIRDTSTARAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0009AC354E ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0005256257 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERISYGAADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA -LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRANDVAVLWPGGGSPLVLSVLTDR -PDRAASGQDELVAEATRRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. rho-1.1 TaxID=2506429 RepID=A0A545ZLV9_9RHIZ ---DAGAQLAALEKRTGGRLGVAVLDTETNISL-GNRETERFPMFSTWKALAAGFVLARVD -QGKEKLDRRVSFGKEALVAYSPVAEKHAGTDMTIAELCEAAITVSDNTAANLLLDSFGGP -AALTDWLRTTGDTETRLDRREPELNEAKKDDPRDTTTPDAMLDTLGLLTLGNTLSDASST -MLTGWLVAATTGKDRLRAGLPAEWKVGDKTGTGAQGMAADIAIVWPPERGPILVAAYIAD -ATAPTAEINAVFAEIGKMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF97C66 -----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGT -SEFKKSLREIGDTVTNPERFEPQLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKENAKYDDKLIAEATKIALD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00114E51F2 --qATHKEFSQLEKKFNARLGVYVIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLITEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B0EC63_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAEVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009448B17 -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPQNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00115DAA0C --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNIIFNKIGGP -KGYEKALRKMGDPVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=A0A410WNS2_BACVA -----DEKFVQLEKKFDAKLGVYAIDTGTNKTI-SYRSNERFAYASTYKVLAAAAVLKKNT ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNNLTPDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR -FTEDAHYDNALIAEAAKVVLNNf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces armeniacus TaxID=83291 RepID=A0A345XIY1_9ACTN ---EAQREFGRIEEKYGARLGVYAVDTRTGREL-SYHADNRFAFASTFKALIAGALLQRDS ---VKELEKRVTYKRSDLVPHSPVTEKHVESGITVREAMDAAVRYSDNTAANLLFRELGGP -DELQAALRRLGDDTTHSDRVEPELNETKPGDIRDTSTPRAMAGSLRAFTVGKALPEDKRK -ILTTMMRTNTTGSKLIQAGAPKGWKVGDKSGAADYGTRNDIAVVWPPGRAPIMLAVMSDR -KSKDAEYDDALVADAAKAAFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF3D5EB -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3FG87_BACCE -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2I5H5_BACCE -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKSLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Prauserella shujinwangii TaxID=1453103 RepID=A0A2T0M1G3_9PSEU ------EEFAELEREFSARLGVYAVDTGSGREV-THRAGERFAFASTIKALLAGAVLRQRS ---LGGLGEVLTYTADDLVSHSPVTERHAGAGMPVRALLDAAVRYSDNTAANVLLDDLGGP -EALTAALREIGDDTTRSDRYETELNTAVPGDVRDTSTPRAMATSLRVFVLGDALPPGERA -FLTELLRTNTTGDTLIRAGVPAGWPVGDKTGAGGYGTRNDIAVVWPPGRDPIVLAVLSDR -DSPDASHDDALVARAAEVVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF4EC42 -------SFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus dakarensis TaxID=1917889 RepID=UPI000B44958F -------VFAKLEDKFDARLGVFALDTGTNQTV-TYRSDERFAYASTHKALAVGALLRQKS ---IADLNQRITYTHDDLVNYNPITEKHVDTGMTLKELCDAALRYSDNTAENLILEQLGGP -SGLEQSLREIGDNVTNPERFEPELNEVEPGETRDTSTPKALAASLQAFTIGDALPAEKRS -ILTDWLKRSTTGDTLIRAGVPKGWEVGDKSGSASYGTRNDIAIIWPPKGDPIVLAVLSSR -DKKDADYDDKLIAQAAKEAI--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1C4DPV5_BACTU -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -QGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1C4DBR8_BACCE -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KRYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces subrutilus TaxID=36818 RepID=A0A5P2UIU8_9ACTN ---STHRALRDLEEEFGARLGVYAIDTGSGRCV-AHRADERFAYCSTHKALTAAAVLDRNS ---LAELDEVVRYCAADLVANSPITEKHVDTGMTLRELCDAAVRFSDNTAGNLLFAELGGP -KAFQAALAALGDRTTRADRVETALNEAVPGDLRDTSTPRALVADLRAYALGDVLPADKRA -VLVDWLRRNTTGGRLIRAGVPADWQVGDKTGAGSYGTRNDIAVAWPPAAAPVVLAVLSSR -PARDAAYDDALIARAARVVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0008FE2680 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAITKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -NKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0E1MK66_BACCE --qATHKECSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP -KGFEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=B5UYF1_BACCE -----NHAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID7810 TaxID=2690329 RepID=UPI00073DF495 -----RAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDLLPNSPRTEENVATGMTVAELCAAAIQYSDNAAGNLLLREVGGP -AGLTRFYRSLGDEVSRLDRWEPELNAAIPGDARDTTTPEAIAESLERLTLGRALAGADRE -RFVGWLKGNRTSDERFRKGLPKDWTVADKTGTGDYASAHDIGVAWTTRGTPVVLAVLSSK -STPDAPVDQALIADAAAVVAR-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D0440C4 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAAAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFD36F4 -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVFK-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. AD80 TaxID=1528773 RepID=A0A2N7RWM0_9BURK ----AEAQLAALEQAAGGRLGVAAWRTDNSARV-SHRADERFPLCSTFKAMLAAAVLARSA -SQPGLLDQHVRYEKKELVTYSPITEKHLDDGMSVADLCAATLQYSDNSAANFLMVILGGP -QAVTAYARSIGNMVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGTSLPAPQRQ -LLDSWMRGNTTGDKRIRGGLPAGWAVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKNAPTNQDIISAATRIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=A0A0S2F6A6_9GAMM ----WSAQLRVLEKNSGGRLGVGMLDTGSGQHF-DWRGRERFPMCSTFKFLLAAAVLREVE -RGKLDLQKKIPIAKSDLIAYSPVTEPLAGSSASVAQLCEATMTLSDNTAANLLLPLVGNP -AGLTAFLRGIGDPTTRLDRKEPELNSAIPGDPRDTTSPLAMVATMRKLLLQDGLQPASQK -QLTAWLVANRTGDKRLRAGVPKGARVGDKTGTADT-TSNDLAIIWLPDRAPILLTCYLTG -STLDGPGRDAIHASVARLVF--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=I6ZR30_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDXQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Polyangium sp. SDU3-1 TaxID=2567896 RepID=A0A4U1HHD7_9DELT -----DAEFTKIEQNLGGKIGIAALDTGSGATL-HHRHDERFPMCSTFKMVLAGAVLARVD -GGKEKLDRTIAYGEAALLEHAPVTRAHVKEGMTVEALCEAIVLVSDNTAANLLLDTMGGP -EGLTAYFRSLGDTVSRLDRKEVELNTAIAGDERDTTTPSAMVSTMKRLLIGDALSPASRE -KLLGWMIACNTGKDRLRAGLPRDWRAGDKTGTGMNGAANDVAIAWPPGRPPVLLAVYAWG -SEGPLPRINAAHAEVAAVVSRFf ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. vignicola TaxID=473426 RepID=A0A220WES6_XANCI ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGVGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4U2P2X6_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3364D -hqATYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus sp. TaxID=229037 RepID=A0A3D2BNA1_9GAMM ---AIEQQLSALEKSTQGRLGVALINTADNSQI-TYRGNERFAMASTSKVMAVAALLKESE -QKADLLDKNISIKQSDLVAYSPIVEKHLTTGMTLAQLSAATLQYSDNTAMNKILAHLGGP -EKVTQFARSINDITYRLDRSEPELNTAIHGDPRDTTSPLAMAKSLQALTLGDALGQYQRN -QLITWLKGNTTGDNSIKAGLPKPWIVGDKTGSGDYGTTNDIAVIWRENQAPLILVIYFTQ -QEQNAKSRKDIIVKATEIVTKPf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI25_KLEOX ---AIHXKLTDLEKRSRGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQE------------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8W2_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQERLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAATTMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B45579C -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KRYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. tolworthi TaxID=1442 RepID=A0A0G4D2Y5_BACTO --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFTSTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2T0E1Y0_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTNWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011559941 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00130DF631 ---NIDEKFAQLEDDFDAQIGVYAIDTGTNQAI-EYRPEERFAFASTYKALAAAIVLQQNS ---MEDLNEVISYSEDDLVPYSPVTEKHVDTGMTLLELAEAAVRTSDNTAGNLLFKALGGP -AEFEQALRDIGDHDTQSDRYEPDLNMFSPEDPRDTSTPKALTTSLRAFVVGDLLSDQARE -RFTNWLQGNATGDTLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNREPIVITIMSRH -NTEDAEYDDALIAQAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis Bt18247 TaxID=1423143 RepID=A0A1C9BTJ3_BACTU --qATHREFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTLGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIISAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis MC28 TaxID=1195464 RepID=K0FM29_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B1C02F --qATHKECSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP -KGFEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF5C10E -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. WN066 TaxID=2547811 RepID=A0A4R5VKE7_9BACI ---QTHREFAELENKYDARVGVYAIDTGTNRKV-SYRSQERFAFASTYKALAAGALLQHYS ---IGQLDELVTYNSEDIVPYSPITQLHIDTGMTLREVIEAAVRHSDNTAGNLLLEKLGGP -EGFETALRKIGDNVTQVDRYETDLNSAVPGDTRDTSTPKALATSLKAFAVSDLLPAEKRK -ILTDWMRGNTTGNALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNTLIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Caulobacter sp. BK020 TaxID=2512117 RepID=A0A4R3GYA2_9CAUL ----ISRNIAALEARSGGRLGVAILDTADGEVF-AHRGDERFAMCSTFKALVAGLVLKRVD -QGQERLDRLIRYGRGVLLAHSPATERHVEDGMTIGALCEATVTLSDNAAANLLLHTFGGP -PALTAFLRGLGDSVTRLDGYEPGLNVVRPGEIHDTTSPRAMLATLRALTLGPVLSPASRQ -QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGDGNTNDIAVIWPPGRPPLLVTAYLSR -STLDDDGRNAVIAEVARLAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000994FB8C -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKTLATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000D63414F -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTSMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGAHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF60994 -----AAALARLEDGLDGRLGVFAIDTASGATL-GHRASERFPMCSTFKAILAGAVLARSW -REPGLLDERVRYTKADLIAHSPITGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP -EALTKQARAWGDSTFRLDRWETALNSALADDPRDTSTPEAMARLLRTLAVDDGLPSAQRA -RLQDWLRGNTTGGARIRAGMPAAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL -EAQDAKPRDDVIAAASRIVA--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Rhizobium TaxID=2613769 RepID=A0A1W6PQ43_9RHIZ ---NIERRLAALEKRTGGRLGVSVLDTQTSISF-GYRGSEAFPMCSTFKALAAGFVLARVD -KGQESLERRVTYGRDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAGNLLLESFGGP -PALTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTAPDAMLDTLGNLTLGSVLTGASCD -KLIAWLVASTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYIAE -ATAPVKDLNPTFAEVGRMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B8TPB4_BACTU -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF955CC -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFDBCCC -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3866 TaxID=422271 RepID=A0A2A3B9A3_9RHIZ ----ATKAVEALEARNGGRLGVMILDIGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD -DGKAKLDDRIVYAASDVEQYSPITKDHVGDGMKLEDVCAAAVVWSDNTAGNLLLRVLGGP -QGLTRFARSLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK -RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG -STAPRASREAVHRDMARIIVETf ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00050F3AFE --qTLESQFKALESKSEGRLGVAVIDTSDGSTY-SWRGNERFPLCSTSKVMAVAAILKKNE -SDYHLLDKKIHINKSDMVNYNPVTQKHTGSYMTVAELSAAALQYSDNAAMNKLLAYLGSP -QQATQFARTIGDKDFRLDRNEPGLNTAIPGDTRDTTTPSAMADSLNKLVLGTALKEAQRT -TLAEWMKGNTTGSNSIKAGLPGAWVVADKTGSGDFGTTNDIAVIWPKNHAPVILTAYFTQ -HSKDATARRDVLASAAKLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000DEEA7C3 ------DSFVKLEKEFDAKLGIYALDTDTSQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPXNKKPIVVAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9R8D1_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKITHRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=A0A136GEC8_9BACI -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7VR90_9BACI ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLINYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKRPIVLAILSNH -EKEDAKYDDMLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00124DFDF5 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B7F1183 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKL ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI0005511B91 ---DLNSRMADLEKRSGGRLGVAALDLKTGQRL-AWRAGERFRMCSTFKAPLAAHVLRRVD -QGREDLSRKVTYGKAVLMGNSPITEKHVADGLTIGQLCEATIAWSDNAAANLLLDAVGGP -KALTRFLRSMDDQVTRCDRYEPELNGGAASDPRDTTTPAAILDTWKTLLLGDALSATSRA -QLTTWLVANRTGGKRLRAGLPPGWRVGDKTGNDGKSITNDIAIAWPADRPPILIAAFLAG -SSPDDDVRNAIHAEAARILV--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=A0A381LR22_9XANT ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI000CEE6500 ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=UPI000B5A1875 -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000BAF2448 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTRAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNTLIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. Co1-6 TaxID=1806507 RepID=UPI0012E098A5 -----DQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALTTDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSHGTRNDIAIVWPPDRAPIVLVILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia sp. NEAU-DD11 TaxID=2683234 RepID=UPI00135F8197 ---DATQALAGLERRAGGRLGVAAWRRGGADVI-AWRGDERFPFCSTAKVMVVGTVLTLAA -RTPGLLDERVRYKKADLVSWSPVTEQHVDDGMTIADLCAAALQVSDNSACNLLLDRIGGP -AAVTAFARRIGDTAFRLDRRETELNAAIPGDPRDTTTPRAMARSLEALLLEEALAPDARR -RLLDWMFANTTGKERIQAGFPADCRVADKTGTGAHGTTNDVGLVFPPQGQPVIVAVYYTG -SKSD----SKVVADAAAIVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0008726FD4 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=R8LNY1_BACCE -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Edaphobacter modestus TaxID=388466 RepID=A0A4Q7YWS7_9BACT --eDLSTTLAALETRSKGRLGVAIL-FPSGKQV-THRADERFPMCSTFKFLAASLILQRVD -QGKEHLDRAVAFSKSDLVTYSPETEKHAGGSMTVAELSKAALTLSDNTAANLLLASFGGP -PALTAFARSIGDPLTRLDRNETTLNESTPGDPRDTTTPNAMLANLQRIFFGNVLKPASRQ -QLTDWMLANTTGKPKFVAGLPSTWKVADKTGSGEHGSNNDIGVLYPPDGEPIFITSYLTE -TAISTDERNAIHADIASAIAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium alamii TaxID=492774 RepID=UPI0005622480 ---DIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRVKYGKEKLVTYSPETEKHAGGDMTMAEICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYIGE -ATVKMDEFNPVFAEIGKMITE-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia psychrophila TaxID=1603353 RepID=A0A2G8SWP6_9BURK ----FARDVAKIEAASGGRLGVAAFDTGRNSQL-SWRGDERFPMASTFKVLAAASILARKP ----GLLATRIRYTQEDLVPYAPVTERHLADGMTNAELCAAAVQVSDNPAANLLMRQVGGP -AGVTAYARLLGDAMFRLDRWEPELNSAIPGDARDTTTPLAMMRTLHKLALGDALAPPARK -LLVDWMLTSTTGAERIRAGVPHDWNVADKTGSGGHGTTNTIAVMWPPGRSPIVIAVYFTQ -SP---RQRNDVVAAAARAVNAAf ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. YR522 TaxID=1144342 RepID=J3HJS6_9BURK ----IAQKLAELEKKSGGRLGVMAIDNASSDRV-GYRQSERFPFCSTFKIVLVGAVLNRSL -EDSTLLQRRLRFGARDLVSYSPVTEKAVGAGMTVSGLCAAALQYSDNTAANLLIAELGGI -GAVNDYARRIGDTEFRLDRTETALNSAVPGDPRDTTTPQAMAQTMQKLTLGELLPALQRR -MLIDWLRGNTTGGARIRAAVTRDWQVGDKTGSGDYGTTNDVAVIWPTNASPVVLVIYFTQ -TAENAPMRNDVVADAARIVIEHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FB68_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTASLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6M907_9BACL ---DADQQLGQLEKEYDARLGIYAIDTETGRTV-SYRPDERFAYTSTFKPLAAGALLLKKP ---LDELDKVITYKKEDLVTYSPVTEKHVEKGMTLREISDAAIRYSDNTAGNLLLKELGGP -AGLETVLQEVGDHITKPERYETDLNEAVPGDIRDTSTPKALATTLKAFTVDGVLPAEKQD -VLIDWLKRNTTGDELIRAAVPEGWTVGDKTGAGSYGTRNDIAVIWPPNQAPIVMAVLSSR -TEQDATYDNALIAKAAKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=BLAC_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKRIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFBE7FC -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVQKRN -ILTGWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWSQNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rummeliibacillus pycnus TaxID=101070 RepID=UPI000C9BFDE9 ----IHREFENLESKFDAHLGVYAIDTGTNRKI-SYRSNERFAYASTYKALAAGALLQQYS ---IDKLDELVTYTSKDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -KGFETALRQIGDNVTQVDRYETDLNSAIPGDKRDTSTPKALATSLQAFAVSDLLHTEKRT -ILTNWMRGNTTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSNR -DTQNATYDNRLIAETANVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLAC_KLEPN ------EQIKQSESQLSGRVGMVEMDLANGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAGIGQ------ ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BF9A2DE -----NDSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDEKITYTREDLSNYNPITEKHVDTGMTLKALADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPKEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001145EDA8 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus polygoni TaxID=1235259 RepID=UPI0011F2120D --qTTDNDFAQLEKEFDAKLGVYAIDTGSGKII-DYQADERFAYTSTFKALAAGAVLQQNT ---MEELNETVTYTKDDLVTYSPITEKHVDTGMTLLEISEAAIRYSDNTAGNLLFNALGGP -DSLEKAMREIGDNVINADRTETNLNEAKPGDIRDTSTPKALATSLQAFALDDLLSESKQN -MLLEWLKTNTTGDTLIRAGVPEDWTVGDKSGAGGYGTRNDIGIVWPPNREPIVIAILSSR -DTEDAEYNDDLIKQATEITVN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar yosoo TaxID=180848 RepID=A0A243C5X2_BACTU -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYQSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEB8433 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. juglandis TaxID=195709 RepID=A0A383SCY1_XANCJ ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLAKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWRIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62418 TaxID=2182391 RepID=UPI000F8F399E ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPITERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuB4-4 TaxID=1053211 RepID=R8S1W6_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides (strain KBAB4) TaxID=315730 RepID=A9VGR9_BACMK -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYNSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=UPI000EFBBCBE -----EAQLATLEQSSGGRLGVFALNTADGKQI-GYRVDERFPFCSTFKVILIGAILARST -QVSGLLQQRIQYSQSDVVHYSAVTAQHVGDGMTVGELCVAAIQHSDNTAANLLIKLLGGP -QAVTAYARLTGNPVFRLDRMETSLNDAVPGDPRDTATPAAMARSLQTLTLGEALPVPQRT -QLLDWLRGNQMGSKRIGAALPAGWSMGDKTGTGDYGTANDLALIWPPSRPPILLAIYQTQ -REQDAKARDDVIAAAARIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C4FP88_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGARNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MDY8_BREBE ----MDLKFAALEKKFNARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAVLHQKP ---LEELDKVITYSKDDLVTYSPITEKHVATGMTLREVADAAVRFSDNTAGNLLFKELGGP -KGFESALRQIGDSVTTSERYETELNEAKPEDIRDTSTPKALATSLRAYTVGDVLSSDKQT -ILIEWLQGNTTGDKLIRADVPKDWKVGDKTGAASYGTRNDIGVIWPPNKKPIVIAVLSSR -DKQDATYDDALIAEATKVAVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001155981B --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IATLNEVITFTTEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNTTGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0KJM5_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASIYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI000F8F7B16 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTMPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 2BBP-J2 TaxID=2719381 RepID=UPI00143202A3 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADHRALVLGDALPAAGRA -LLTDWLVRNTTGDRRIRAGAPRGWRVGDKTGSGDWGRGNDVAVLWPGGGPPLVLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=E5G517_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDPGGTELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. F-7 TaxID=573566 RepID=UPI000A98E004 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAANLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADHRALVLGDALPAAGRA -LLTDWLVRNTTGDRRIRAGAPRGWRVGDKTGSGDWGRGNDVAVLWPGGGPPLVLSVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI001316B3DD ---DLDETFATIESDYDARVGVYAIDTGSDETI-DYRSEERFAFASTYKALAAALVLKQNT ---MEELEEVITYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGDLLTDDKRE -RLLDWMQGNATGDTLIRAGATEGWTIADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH -DTEDAEYDDALIAEVAEATLN-- ->[subseq from] UPI001447CAB8 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001447CAB8 ----LEKTVTGAESRLSARIGVAVLDTETGKTW-THRADERFPLNSTFKAFLCAALLEKGE -QGEVQPERRVKIRSQDLVSYSPVTEKKVGSGMTYLELCEAAVAISDNAAANLVLEAVGGP -AGLTDYLRGIGDTITRLDRTEPGLNEGRPGDARDTTTPAAAVATLQKLVLGDALSSTARV -QLTGWLLDNKVGNATLRAGLPEEWPVADKTGAGANGSRNNIGVIWPDDREPVVIAVYITQ -TDASFDDRNKAIADIAAALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Erwinia typographi TaxID=371042 RepID=A0A0A3YXT8_9GAMM --pALRQQLASLEKQVNGRIGMALLDTDSGRTL-SYRGQERFAMCSTFKLLAASAILHRSQ -QQPGLLQKRLRWQAADAVPYMPITEKHLHDGMTLAGLCAAALQYSDNLAANLLLKELGGP -SAITRFTRLLGDTVTRLDRHEPELNTAIPGDPRDTTTPLNMIGNLHQLALGKGLKDREQQ -QLVRWLKGNTTGKKAILAGLPAGWVVGDKTGSGGYGTTNDVGVLWSPEGKTLVMAVYFTQ -HDKNASSRQDVLAQVASLT---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2J9BFQ0_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYTSTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylibium sp. CF059 TaxID=1500261 RepID=UPI0006460178 ------AHWKAIEDSARGRLGVAVLDTADGRID-GHRLDERFPMCSTFKWLAAAHVLQRVD -VQQEQLDRRIRFGREVLVPNSPVTSKAAGGDLTLAELCEATITVSDNAAGNLILQSYGGP -AALTRYARTLGDTKTRLDRWEPELNEARPGDPRDTTTPRAMTTALRATLVGDALSPAGRE -QLRRWMEATRTDVKRLRADLPEGWHLASKTGTGARGSTNNVGVFWPPGRPPIVVAVYLTE -AHAGEAARNAAVAQVARVVT--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A4U8VXH4_9NOCA -------QFAELETTAGARLGVFAVDTGSERTV-AHREHERFPMASTFKGLACGALLREHP -LSTGYFDQVIRFSAAELVEYSPVTETRVESGMTVAELCHAAITVSDNTAGNQLLKLLGGP -QGFTAFLRSLGDNTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDVLGEPERA -LLTSWLVANTTGGTRIRAGLPADWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLTTK -SEQDAEPDNELVADATRAVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A5Q2ZM04_BACIU -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKRNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI001012019B --aDTLSTVKQAETTLAARVGYAELDLASGKVLgSYRVNERFPMMSTFKVLLCGAVLARVD -AGQEQLDHRLRWQKTDLITYSPVTEKHLADGMTVAELCDAAITMSDNTAANVLLSTLGGP -QKLTAFLRKTGDAVTRLDRVEPELNEALPGDVRDTTTPEAMAKTLRQLLTGNTLSAASRQ -QLARWMEDDKVAGPLVRSVLPAGWYIADKTGAGERGSRGIVAALGPDGTPSRILVIYVTG -SSATMDERNKQIAAIGEAVIKQw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=UPI000BF99398 -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -EKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase 3 n=1 Tax=Bacillus cereus TaxID=1396 RepID=BLA3_BACCE -----NHAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Ramlibacter sp. 18x22-1 TaxID=2530451 RepID=A0A4Z0BEK3_9BURK --------WAAIEASARGRLGVAVMQ-ADGSVH-GHRLDERFPMCSTFKWLAAAHVLRRVD -RGQERLDRRIRYGREVLKPHSPITRQQVGEGMTLGELCHATITVSDNAAANLILGTFGGP -QGLTRFARGLGDKATRLDRWEPELNEARPGDPRDTTSPRAMAGLLHATLVGDALSPRSRE -QLAAWLQATTTNGQRLRADLPAGWRMGSKTGTGARGTTNDAGIFWPPGRPPVIVAVYLTQ -SDAPEAARNGAAAQVARWVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=UPI000A3222C6 ---DFHAACARLERAHDRRLGLYAIDTGNGRTV-GYRAGERFAFCSTFKALLAGAMLARLK -ADAGILDRRILYTRHDLVPYSPITEKHAGGSMTVADLCAAALQYSDNTAANLLLHAVGGP -AALTGYARALGNRSFRLDRYEPALNSAIPGDPRDTVTPADMAASLRTLAVGNALTAGGRE -RLREWLLGNTTGANRIQAGAPAGWRVGDKTGTGDYGAANDIAIVLAPDRPPIVLAVYTAA -SATDAAADEPLIAAATQLAI--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4PWK0_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAMGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XP18_BACCE -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. WMMA2032 TaxID=2039870 RepID=A0A2D1I4E3_9ACTN -----DRAFRQLEETFDARLGVYAIDTGTGTTV-GYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITEKHVADGMTLRALADAAVRYSDNTAGNLLLRRLGGP -QRFEKELRGVGDKVTAPARYETALNEARPGDRRDTSTARALAQDLRAYAVGDSLDPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVVWPPDRAPIVLAVLSSR -DQKDADYDNALIARAAEVAI--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0XLN8_BACCE -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=A0A268DWS5_9BACI ----TNKKFVQLEKKFDAKLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMRLKEISEAAVRYSDNTAGNLLLQQLGGP -TGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRM -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALISEAAKAALD-- ->[subseq from] Beta-lactamase n=1 Tax=bacterium enrichment culture clone F7(2012) TaxID=1155062 RepID=H9AZ20_9BACT --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYQPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPALNEVNPGETQDTSTARALATSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAGSYGTRNDIAVIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y9Q5_9BACL ---AMDQKFAALENKFDARLGVYAIDTETDLAV-AYREDERFAFASTYKALAAGAILHQKP ---LEELEKVITYTKDDLVTYSPITEKHVATGMTLREVADAAVRYSDNTAGNLLFKELGGP -KGFESALRQMGDLVTTSERYETELNEAKPEDIRDTSTPKALATSLRTYTVGDVLSSDKQK -ILIEWLQGNTTGAKLIRSGVPKGWKVGDKTGAASYGTRNDIGIIWPPNKKPIVIAVLSSR -DKQDATYDDVLIAEATRIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora deserti TaxID=2070366 RepID=A0A2W2DN53_9ACTN ------PRFGQLEAEFGARLGVYAVDTGSGRTV-EHRADERFGYASTFKALAAAAVLDETT ---TAELDQVVRYTAADLVDYSPITKDRVGSGITLREAADAAVRYSDNTAANLLLDRLGGP -AGFEKALRELGDQVTDPERRETALNDVAPGETRDSTTPRAFATDLRAYVVGDALSAEDRD -VLVDWLRRNTTGDKLIRAGVPAGWTVGDKTGGGPYGIRNDIAVVWPPDGAPIVLAILSSR -TEKDDEYEDALIAEAAKATI--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=C2XUB5_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD0967 --dDIDKRLAALEARIGGRLGVSVLDSDTNVSF-GYRGSEPFAMCSTFKVLAAGLVLARVD -KGDESLDRRVTYGKDKLATYSPETEKHAGGDMTMAEICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSVLAETSAN -QLVDWMIANTTGGARLRAGLPSDWKIGDKTGTGDNGSAGDIAIIWPPKRGPIVAAVYMAE -TTVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFB2455 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREELVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF98880 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREELVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVLPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q8GEA5_KLEOX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNR------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8GEA6_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDHWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNR------------- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter rhizosphaerae TaxID=2010972 RepID=UPI0013D763B9 ------RGMAALEARSGGRLGVAVLDTADGRTF-AYRGDERFAMCSTFKALVAGLVLKRVD -QGQERLDRRIVYGRNVLLAHSPATEQHINDGMTVGALCEATVTLSDNAAANILLYTFGGP -PALTAFLRGLGDKVTRLDGYEPNLNVVRPGEIHDTTSPNAMLGALRALALGPVLSSASRQ -QLVAWLVANQTGDKRLRAGLPAGWKVGDKTGSWGDGTTNDIAVIWPPGRPPLLITAYLSR -STLADDGRNAVIAEVARLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI00091C1D11 ---TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSA -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=Q84HU2_ECOLX ---ETLVKVKDAEDKLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBC3C5 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGMEKLDRRVTYGKDKVVTYSPATEKHADTDMTVGELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAAKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKTGDKTGTGNNGSYADIAVIWPPDRGPVLVTTFVAD -ATAPAKDVETVFAEIGKIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0012FB5050 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKTLATSLQAFTLGDILSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2IAW6_BACCE -----NDSFAKLEKEYDAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTHSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3MWW4_9ACTN ----HDREFRLLEERFDARLGVYAIDTGTERTV-AYRADERFAYASTFKALAAAEVLDETT ---DAELNRVVRYSADDLVTYSPITQQHVADGMTLREIADAAVRYSDNTAGNLLLRQLGGP -QRFEKKLRAIGDTVTDPARYETALNEARPGDRRDTSTARALAQDLRAYAVGDALAPADRD -VLTGWLRGNTTGGELIRAGVPDGWAVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSGR -DEKDADYDNALIARATEVVIS-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A242ZDL2_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNP ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus cereus TaxID=1396 RepID=R8KHX3_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFB336D -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILVILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFDDF07 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEVLDQRITYTNEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A0B7G5U6_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPVVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTHLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. 3H-10 TaxID=2672567 RepID=A0A6B3VUN7_9BACI ---SASREFADLESKFDARLGVYAIDTGTNRTV-SYRPNERFAYASTYKALAAGALLQHYS ---IDQLDELVTYTSEDIVTYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -EGFETALRQIGDNITQVDRYETDLNSAIPGDKRDTSTPKALATSLKAFAVSDLLPTEKRM -ILTDWMRGNTTGDALIRAGAPKGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNTLISEATKVALN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0010BD627A --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEAIYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0012988F66 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A168D6V1_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=UPI0012DF227F ----TNKKFVQLEKKFDARLGVYAIDTGANKTI-AYRPNDRFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYHNALISEAAKAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G7DA42_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001144274D --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNMLFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=environmental samples TaxID=48479 RepID=X2KZE3_9BACT -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00087203BB ------DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00119F7C1B --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKVLRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00114598E4 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIIFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2X4Y9_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2T7YL80_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEAIYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9E539_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKTIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000A27C80B -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNP ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B6A35D -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVFN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobacter gummiphilus TaxID=946333 RepID=A0A1W6L688_9BURK ------SGLADLERTVGGRLGVAVLDSATGGLT-GRRLDERFPMCSTFKWLAAAKVLQRVD -AGEESLERQLPVSAADILDHSPTTGKHVGGSLSLGELCDATIALSDNAAANLILATYGGP -AAVTAFARSAGDPATRLDRTEPALNESREGDPRDTTTPAAMARTLRAVLLGDVLKPASRQ -QLTAWMLGTQTSGERLRKDLPAGWRLADKTGTGSNGSANDVGVFWPPGRPPVVVAVYLTG -GKAPLERRNAVIATVAA------ ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0010517BA5 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGLPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEVTYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000627825C -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0002F74658 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001009ADA4 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKIVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Xanthomonas perforans TaxID=442694 RepID=A0A0G9F3Z5_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADDDPRDTTTPAAMAATLRTLLLGDALHPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FD89_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KEPTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A381KS28_BACCE -----NHAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A410YSW5_BACIU -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF32896 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLKKKS ---IEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTPKALATSLQAFALGDVLSTEKRD -LLKDWMKKNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5KN16_9BACT ---EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -IGLTNFARTIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH -QLEQWLQANQTGASMIRAGIPTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG -STATANDHAAVLAEAAKIVI--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9WTW2_9ACTN -----DHEFRQLEERFDARLGVYAIDTGTGRTV-QYRADERFAYTSTIKALAAAEILDETT ---DAELDRVVRYSADDLVTYSPITEQHVGDGMTLREIADAAVRYSDNTAGNLMVRQLGGP -QKFEKELREVGDKVTDPARYETALNEAKPGDRRDTSTPRALAQDLRAYAVGDALEPADRD -ILNEWLQGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVICPPDRAPIVLAVLSSR -DQKDASYDNALIAEATKVVMAGw ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas sp. Z24 TaxID=2382222 RepID=A0A3A9JG65_9PROT -----PAAFAQIEAARGGRLGVAVLDTGSGQGT-GYRQDERFPLASTFKLLAAAAVLARVD -AGQDNLDRRIRFKREDLVTYSPTTGQHAGADMTLAEIAGAAVTLSDNTAGNLLLNVLGGP -AGLTAWLRQQGDAVSRLDRMETDLNEASPGDPRDTTSPAAMLRHLQAVTLGDALSPASRA -RLRGWMRASSTGDNCLKARLPQGWVVEDKTGSGGNGTRNDVALLWPPGGAPMLVAAYLTG -GASEIAARDAVLADVGAAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodobacterales bacterium TaxID=1948890 RepID=A0A5D0VBW8_9RHOB ----LEAAVAEAEGSLHARIGVSVIDTETGATW-SHKGGERFPMNSTFKSFLCAALLDAAQ -KEEADLSRSVTIEESDIVRYSPVTEKRVGGSFTLEQLCETTVTYSDNAAANIVLEEIGGP -EGLTAYLRSIGDTVTRSDRPEPDSNSGIPGDPRDTTTPDAAAETLRKTVLADALSKPDRR -KLASWLVDNKVGDKTLRAGLPKDWVIADKTGAGANGSRNDIGVIWPEGRKPVVIAVYITQ -TKAAFDDRNKAIADIAAALVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI000247CB7E ---MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A410R118_9BACI -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0006182C6C -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7D281_BACCE -----NNSFAKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLLQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000D883779 -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFKKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVEWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. UNC437CL72CviS29 TaxID=1340430 RepID=UPI0009E0A8BC ---ATHQKYAQLEKKFDARLGIYAIDTGTNRTV-SYKQNERFAFASTYKALAAGALLMQNP ---IDKLNEVIIYTKDDLVEYSPITEKYVDTGMTLGEIAEAAVRYSDNTAGNLLFKELGGP -EGFETALKQIGDRVTQADRFETDLNEAIPGDIRDTSTAKALATDLKAFTAGNALPADKRK -ILTDWMHGNATGDKLIRAGVPKDWEVADKSGAGSYGTRNDIAIVWPPNREPIIIAILSSR -DTKDATYDNELIAQAATITIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0007C1B4CD -----HDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLESALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYSDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=9 Tax=Bacteria TaxID=2 RepID=A0A089NF48_9BACT -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEGLNQRVLYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPEHFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKKNTTGDSLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKJ3_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRTHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAADLLLATIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDRMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIG------- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium DB1506 TaxID=2230885 RepID=A0A327ML67_9PROT ----LPAALQRIERESGGRLGFVMLESGSGGGA-AHRPAERFPMCSTFKLLAAAAVLARVD -AGQERLERRVRFGRAALVPYSPITEQQAEGEMTLAALAAAAIGYSDNTAGNLLLEAIGGP -AGLTGFARGLGDAVTRLDRIEPALNEALPGDPRDTTSPMAMLTDLRRLLLGDALSAAGRE -RLTGWLLGSRTGDSRIRAGLPAGWRFGDKTGSGERGTTNDVGIVWPPGRPPVLFAAFLTE -TEAGMEQRNATLAAVGRAMA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF61D08 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A519EWU2_PSESP ---AIAQQLAELERRHGGRLGVAMLDTSSQRLI-SHRGDERFALCSTFKCLAAACVLARVD -QKHEDLSRRIVYSAEQLVAYSPTTELHAGGQLSVGSLCEAAMTLSDNTAANLLLDSVGGP -EGLTAWLRSMGDTQTRLDRREPELNENRPDDLRDTTTPVAMLQTLNTLVLGEKLTPASRD -QLTAWLVNNQTGDKKLRAGVPVSWRVGDKTGSGANNASNDVAVIWPGERGLMLVTAYYTG -SRASGDQINALMADIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000893B095 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGVTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2323.1 TaxID=1938841 RepID=A0A286HYA7_9ACTN ---DAHAALRRLERANRARVGAYAHNTVTGATV-AYRADTRVPLCSVFKTLAGGAVLRDLD -HHGETLARRVHYTDADLVANSPVTSKHLATGMTIAELCAAALQRSDNTAANLLLRALGGP -TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIARTYTRLLLGDALTPADRA -RLTAWMKANETNTDRFRAGLPRDWTLADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGK -AQQAATPDDPLVADVTRVLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Deltaproteobacteria bacterium ADurb.Bin207 TaxID=1852869 RepID=A0A1V5X6S5_9DELT ----REAAWESIETTSGGRLGVAIFDSANGAWT-GHRIDERFPMCSTFKWLAAAYVLHRVD -RGQEKLDRRIRYGSDALLPWSPETEKHADGSMTVAELCEAAIAMSDNTAANLILKALGGP -SALTHFLRTQGDTVTRLDRWEPDVNTSIPGDGRDTSSPRAMATLLRRWVLEPTLSDGSRE -RLVQWLRSTKTNTHRLAAGLPTGWKLGSKTGTGPYGTTNDVGVYWPMGRAPIVAAVFLTE -SEKSQENREDALARVARMVF--- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillaceae bacterium GAS479 TaxID=1882832 RepID=A0A1H2B6C0_9BACL ---AFRRSFVQLEEKYGARLGVYAIETGTGRSI-AHRPDERFAYASTYKALAAGFVLKHST ---ANELERVITYSKDDLVSYSPVTELHVNTGMTLKQLCEAAVRYSDNTAGNLLFKQLGGP -KGYEVALREIGDVVTQVDRLEPELNEAVPDDTRDTSTPRALATILSNFTVGDVLADDKRS -ILMDWMSGNATGDELIRAGVSEDWKVADKSGAGSYGTRNDIAVVWPPSGAPVVIVIMSSR -DEQNADYDNALIAEAAKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF28D57 --------FVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. phaseoli var. fuscans TaxID=473423 RepID=A0A2D2RTB1_XANCI ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLARQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGVGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEE4CA7 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELGDASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A151UPR3_BACCE --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEVAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKGATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0008FDCEE7 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNIIFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKATATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. COPE52 TaxID=2233998 RepID=A0A345X4C1_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar pirenaica TaxID=180863 RepID=A0A243JLZ7_BACTU ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDGRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0A7HFD6_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRESCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Proteus hauseri TaxID=183417 RepID=A0A410XDR0_PROHU ---AIEQQLAALEKSSQGRLGVALINTTDNSQI-IYRGNERFAMASTSKVMAVAALLKESE -QKADLLDKNISIKQSDLVAYSPIVEKHLTTGMTLAQLSAATLQYSDNTAMNKILAHLGGP -EKVTQFARSINDITYRLDRSEPELNTAIHGDPRDTTSPLAMATSLQTLTLGDALGQYQRN -QLITWLKGNTTGDNSIKAGLPKQWIVGDKTGSGDYGTTNDIAVIWRENQAPLILVIYFTQ -QEKNAKPRKDIIVKATEIVTKPf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock4-18 TaxID=526988 RepID=A0A2I0RBJ7_BACCE -----NHSLVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTNKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atriruber TaxID=545121 RepID=UPI0006E3D9C8 ----TLRRLRALEDAYPGRIGVHALHTGTGAVV-AYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDVLIRYGRDDLVAHSPRTEMHLETGMTVRELCDATITYSDNAAANLLMRRIGGP -SGITEFARSLGDPHTRLDRWETDLNTNIPGDRRDTTTPASMTANLRKLVLGKALHPLDRG -QLTRWLLENTTGDKRIRAGLPKEWRVGDKTGSPAYGGVNDVAVAWPPKRAPLVISVYTTR -LDPDTPGEDRIAQDITRIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Motiliproteus sp. MSK22-1 TaxID=1897630 RepID=A0A1R1MHV2_9GAMM --eEFQKKIAAIESKLDGRIGVAILNLHSGDKW-TYKADSRFPVSSTFKVQLCGAILAKVD -AGKESLNRPITFKKSEIVSWSPITEKRVQTGMSVGELCEATITMSDNTAANLLLDMIGGP -QGLTMFLRKIGDDITRLDRWETKLNEGVPGDLRDTTTPTAALGTLEKLLFGKVLSMSSRK -QLTDWMINDKVADDLLRTSLPEGWKIGDKSGAGGYGSRSIIAFIMPPNKGPTLVTIYLTE -NEVDFSTRNRMIAEIGRLIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B3X6S7_BACTU --------FVKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00084A1D41 ------QKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKAYRFETDLNSAIPGDRRDTSTAKALATDLKAFTLGNTLTTDKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDADYHNALIAEAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. HM5-17 TaxID=2487710 RepID=A0A3N2P9B2_9ACTN -----SPEFGRLESRFDARLGVYAVDTGTGRTV-EYRADERFGYASTFKALAAAALLDATT ---SAELDRVVRYTEADLLAHAPITRQRVRTGMTLRELAEAAVRYSDNTAANLILDRLGGP -DGFERALRDLGDRVTNPERREPGLNDVRPGDTRDTSSPRALATDLRAYVLGDALAAEDRD -LLVDWLRRNTTGDRLIRAGVPAGWTVGDKTGSGSYGTRNDIAVVWPPDGAPIVLAVMSRR -DERHATYDDALIAAATRAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. FBKL.4005 TaxID=2015515 RepID=A0A255PB99_9ACTN -----RAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDLLPNSPRTEENVATGMTVADLCAAAIQYSDNAAGNLLLREVGGP -AGLTRFYRSLGDEVSRLDRWEPELNAAIPGDARDTTTPEAIAESLERLTLGRALAGADRE -RFVGWLKGNRTSDERFRKGLPKDWTVADKTGTGDYASAHDIGVAWTTRGTPVVLAVLSSK -STPDAPVDQALIADAAAVVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A502DYB0_9BURK ---DLHLRLRQIETESGGRLGVCILNTADGRRF-GHRMDERFPMCSTFKLLAAALVLQRVD -SGQEMLGRPIAIERSAIVPHSPLTEPNVGGTMTMGALCEATITQSDNAAANLMLASFGGP -GGLTAYVRSLGDPSTRLDRNEPSLNEAIAGDPRDTTTPAAMLGLIQTLLLGTALKPASRD -QLRNWLLANKTGDARLRARLPAGWRVGDKTGAGAFGTNNDVGIVWPPGRAPILVTAYLTQ -TQAPLDRRNAALAAVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CF258 TaxID=1500300 RepID=UPI00055C858E --nDIEKQLAALEKRTGGRLGVFVLDTSTNVSF-GRRQDERFAMCSTFKALAAAFALARAD -KGEEKLDRRIPVLKKDLLSYSPVVEKHVGGGMTVRELCDAAVTYSDNAAANLLLASFGGP -KGLTTWLRSIGDETTRLDRTEPELNEAKIGDPRDTTTPMAMTETLGRLLLQDVLSPSSRD -QFTAWLVANTTGDRRLRAGLPQDWMIGEKTGTSGRGEAGDIGFMRPREGHTILASVYIAE -GKKPTKELEPLFAEVGKLIA--- ->[subseq from] Beta-lactamase n=2 Tax=Salinisphaera shabanensis TaxID=180542 RepID=U2G169_9GAMM ---DFAATMHKLEKRHGGRLGVCVLDTGSDRYI-AQRGDERFLLCSTFKVVAAAMILSRVD -AGEESLDRHIDYATADLVTYSPETEKHAGTGMTLGAICRAAITLSDNTAGNLMLQSLGGP -KALTAFMRSLGDDVTRLDRYETALNEYTPGNPHDSTTPRAMVGLMQKILLGDRLTSSSRD -QLIARLEANETGDNRLRAGLSESWRIGDKTGSGGNNTANDIAITWPEGGAPVLIATYYTG -SSASKAQRDRVLADVGAVAA--- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000BAC5108 --------------------GMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLEWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=5 Tax=Xanthomonas TaxID=338 RepID=Q8PHT7_XANAC ---MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A136C6T7_BACCE --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPITEKHIDPGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A519ENW9_9BURK ---DLHLRLRQIETESGGRLGVCILNTADGRRF-GHRMDERFPMCSTFKLLAAALVLQRVD -SGQEMLGRPIAIERSAIVPHSPLTEPNVGGTMTMGALCEATITQSDNAAANLMLASFGGP -GGLTAYVRSLGDPSTRLDRNEPSLNEAIAGDPRDTTTPAAMLGLIQTLLLGTALKPASRD -QLRNWLLANKTGDARLRARLPAGWRVGDKTGAGAFGTNNDVGIVWPPGRAPILVTAYLTQ -TQAPLDRRNAALAAVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. JAB6 TaxID=2127050 RepID=A0A2T3ECY1_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGAEKLDRRITYGKDKVVTYSPETEKHAGGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAAKGDPRDTTTPDAMLDSIGLLTLGNTLSDTSRE -QLVNWLVANTTGNNRLRADLPKEWKVGDKTGTGNNGSYADIAVIWPRDRGAILVATFVAE -ATAPAKDVEAVFAEIGKIVV--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A7D7A4_BACAN -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHSDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Uncharacterized protein n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1G0HAN5_9GAMM ----INEKFKNLETSLEGRIGLYAINTANNQSI-QYRALERFPIQSTFKVMAVSAILKQSE -ADNNLLKLKITYTKQDLVFWSPITEKYVDDGMTIFDLCAAAMMYSDNTATNLIVKKSGGP -EAVTAFARSIGDNTFRIDDWEPDLNSN-PNDLRDTSTPKAMEKSLQKLTLGDVLTSSKRN -QLVTWMKGNTTGDTRIRAGVPKGWIVADKTGAGDYGISNDIGIIWPPNCAPIVIAIYFGH -NKKDTTRRDDILASSTQLVINEf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 18055 TaxID=2681403 RepID=UPI00135B9B91 ---EIDRRIGALEKQIGGRIGVSVIDTQTNISF-GYRETESFPMFSTFKVLAAAMVLVRVD -KGEENLERRIVYDRSQIVGYSPETEKHVAGEMSVGELCKAAITQSDNTAANLLLESLGGP -KELTNWLRTLGDGSTRLDRIEPDVNEARKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN -RLVEWMVANTTGNERLRTGLPDSWKIGDKTGTGKSGAAADIAIAWPPGHGPILIAVYVAD -ATVPTAEINPVFGEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1W6A8Z9_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKSLAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. malvacearum TaxID=86040 RepID=A0A221MSD1_XANCM ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVNDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus novalis TaxID=220687 RepID=UPI000825F18B ---QLHREFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS ---IDQLDELVTYNSEDLVSYSPVTQLHVDTGMTLREVAEAAVRYSDNTAGNLLLEKLGGP -EGFETALRKIGDNKTQADRYETDLNSAVPGDTRDTSTPKALATSLQAFAVSDLLPTEKRT -ILTDWMRGNATGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAVVWPPNRAPIVIAVLSSR -DTQNATYDNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D5TSG0_BACSP --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHIGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A6D1UUW2_BACCE --qATHKEFSQLEKKFDARLGVDAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. fuscans TaxID=366649 RepID=A0A2H1SN20_XANCI ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVSERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces olivoreticuli TaxID=68246 RepID=UPI000E23E847 --dALTERLKELEREHSARLGVYARDTATGRTV-LYRADERFPMCSTFKTLLAAAVLRDLD -HHGEFLAKRIRYTKKDTDAYAPVTGKNLRHGMTVSQLCSATVSYSDNAAANLLLHELGGP -NAITRFCRSTGDGTTRLDRWEPDLNSAEPERRTDTTTPRAIGQTYARLTLGDALDPKDRK -RLTGWLLANTTSAERFRAGLPADWTLADKTGAGKYGTNNDVGITWPPHRPPIVLSVLTTK -HDREAAADNPLIARTAALVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7GT95_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F6D5_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKILLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B433A0E ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNIVFNKIGGP -KGYEKALRQMGDRVTLADRFEPELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNTTGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Root487D2Y TaxID=1736547 RepID=UPI000700A504 -------GIVALEARGGGRLGVSVLDTADGKTF-AYRGDERFAMCSTFKALVAGLVLRRVD -QGLERLDRRIVYGKSVLLAHSPATEKHVGEGMTVGALCEATVTLSDNAAANVLLYTFGGP -PALTAFLRGLGDKVTRLDGYEPELNVVRPGEIHDTTSPNAMLATLRALTLGSTLSPASRR -QLIAWLVANQTGDARLRAGLPAGWKVGDKTGSWGIGTTNDIAVIWPPGRSPLLITAYLSR -STLGNDGRNAVIAEVARLVT--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B585C2 --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPITEKHIDPGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF54033 -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000EA227A3 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -NGYEKALRMMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Siccirubricoccus sp. 1-3 TaxID=2595053 RepID=UPI0011F0E139 -------PLAALEARHGGRLGVAALDTGSGRAL-AHRADERFPLTSTFKFLAAALVLARVD -AGEERLDRHLAYGESALVPYSPVTGPAAARGLTMAEACDAAVTLSDNTAGNLMLDSFGGP -AGLTAWLRRIGDAETRLDRRETELNEAAPGDKRDTTTPAAMLATMRTLLLGEVLSPTSRA -RLLAWLEGCRTGDRRLRAGFPAGWRLGDKTGSGGRNSTNDVAIAFPPGRAPLLVAAYYIG -ADVPMAEREAVLAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Alsobacter sp. SH9 TaxID=2109933 RepID=A0A2T1HZ82_9RHIZ ----LVATIREVEARLGARVGASVFEVGSGRRW-SHRAEERFPIASTFKAFACAALLARVD -GGQKRLGDEVAIRSSDLVTYSPVVEKHVGGAMTLGDLCAAATALSDNAAGNLILDNIGGP -AGLTAFMRGIGDEATRLDRRETELNEAAPGDPRDTTTPAAAADSLRKLLLGDVLSPKSRR -QLQDWLVANQVGGPLLRASLPQGWRIADRTGAGGRGTRNVLAAIWPPGREPVCAAIYLTG -TEASMDARNAAIAEIGRTLV--- ->[subseq from] Beta-lactamase n=1 Tax=Rubrivivax benzoatilyticus JA2 = ATCC BAA-35 TaxID=987059 RepID=F3LTI8_9BURK -------AFGAIERSVAGRLGVCAYDLETGRSL-GHRQDERFAMCSTFKWLLAAAVLARVD -RGQERLERRIVFGREALLEYAPTTSRHAGGAMTVAELCEAALTLSDNTAANLLLDTLGGP -GGLTAWVRTLGDRTTRLDRREPDLNEARPGDERDTTTPAAMVLALRQAVFGGALSRRGGD -LLLQWMTASTTGLKRLRAGFPPDWRVADKTGTGAQGTTHDVAVVWAPGRAPLLLAAYLTE -SQAPIEAREAALARVAAR----- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus sp. 160 TaxID=2052660 RepID=A0A345PLP5_9BACI ---TINNDFAKLEDEFDATLGVFALETGTNQRV-TYRPDERFAYTSTHKALAVGALLQQNS ---VEDLNQRITYTQDDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -SGFKKALHEIGDDVTNPVRMEPELNEVHPGETHDTSTPRALATSLQTFTLGDVLPTEKRE -LLIDWMKRNTTGDTLIRAGVPEGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAILSKR -DAKDATYDDKLVEQATKVVLK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. H1a TaxID=1397276 RepID=UPI000468452C ----SNQSFAKLEKEYGAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. PDC80 TaxID=1882827 RepID=A0A1I5JF52_9BURK ---DAEARLAALERDCGGRLGVHALDTGSGARI-AHRGNELFPMCSTFKLMLAAAILQRGT -AEPALLERRLSYTRAHLLPNSPITEKHLAEGMTVAELCAATLQYSDNAAANLLMHQLGGP -AGVTAYARSIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALGAPQRA -RLDGWLRGNTTSKERFLAGVPAGWAVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF -PGKGAKTRNDVVASAVRIVAN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2T0EYP1_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKTLRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. Root1485 TaxID=1736472 RepID=A0A0Q7XUP5_9BURK ---DATQALAGLERRAGGRLGVAAWRRGGADVI-AWRGDERFPFCSTAKVMVVGTVLTLAA -RTPGLLDERVRYKKADLVSWSPVTEQHVDDGMTIADLCAAALQVSDNSACNLLLDRIGGP -AAVTAFARRIGDTAFRLDRRETELNAAIPGDPRDTTSPRAMARSLEALLLEEALAPDARR -RLLDWMLANTTGKERIQAGFPADCRVADKTGTGAHGTTNDVGLVFPPQGQPVIVAVYYTG -SKSD----SKVVADAAAIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B3KP92_BACTU ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLESFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. BPN334 TaxID=2217815 RepID=UPI0011EE4E1B -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar sinensis TaxID=1042875 RepID=A0A243MN57_BACTU -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF54B87 -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYVDTGMTLKELVDASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4AYT1_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTPEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Catenuloplanes japonicus TaxID=33876 RepID=UPI000A10F1CE -------VYQQLERRYDARLGVYAVDTGSGRTV-TFRGDERFAYASTFKALAAAAVLDRIS ---DADLHRVVHYTRADLVDYSPVTELHVDEGLTVGAIAEAAITVSDNTAGNLLFRELGGP -DGLERALRAIGDRTTSADRIETELNTAIPGDRRDTSTPRALATGLRAYTLGRELCATDRQ -QLITWLRANTTGAATIRAGVPDGWIVGDKTGAGGYGTRNDIAVLWPPSGAPIVIAVMSTR -DTPDATYDNALLADAAEAVV--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Enterococcus faecium TaxID=1352 RepID=UPI00143337B5 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDA---------------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF3620E --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNA ---MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEQALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI00128BF473 --tEMKDDFSKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAASYGTRNDIAIIWPPKGDPVVIAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] class A beta-lactamase n=2 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI0002D3AAA2 -----DEKFAEIEKEYNARLGVYAIDTGANQRL-QYNPDDRFAYASTFKVLASAILLKQNS ---IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP -EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE -LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH -EEEDAEYDDALIAKAAEIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Aphanothece cf. minutissima CCALA 015 TaxID=2107695 RepID=A0A2T1F1V2_9CHRO ---AAEAGLAALEARSGGRLGVFAIDTASGARI-GHRAGERFPLCSTFKAILAGAVLHRSQ -RQPGFLEQRIRFGRQDLVSHSPIAEQHLEGGLTVEEMAAATVQTSDNTAANQLMARLGGP -AGLTAFARSIGNRTFRLDRWETALNSAIPGDPRDTDTPAGMGTSLQALVLGTALGPPQRQ -RLQDWLIGTTTGDRRVRAGVPSGWQVGDKTGTCGYGTANDVAVLWPPDRAPIVLAVFHTQ -ADPAAAAQDGVIAEAATIVAGAf ->[subseq from] class A beta-lactamase n=1 Tax=Halobacillus sp. Marseille-Q1234 TaxID=2686092 RepID=UPI0013D3FFE6 ---KTDEKFSKLENEFDAQLGVYALDTGTDQTI-EYQSEERFAFASTYKALAAAIVLQQKS ---KDELEEVITYTEDDLVTYSPVTKKHVDTGMTLLELSEAAVRTSDNTAGNLLFKALGGP -NEFEQALRQIGDNVTQADRIEPDLNEFTPGDTRDTSTPKALATSLKEFAVGDLLSNDKRE -LFTDWLKGNATGDALIRAGAPEGWVVGDKSGAASYGTRNDIAVVWPPNREPIVIAIMSHR -DQEDAQYNDELIAQAAEIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF75003 ------DSFVKLEKEYDAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=C2R8E3_BACCE --qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=A0A1C3U0P5_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFALTRVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP -AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGSFADIAVVWPPDRGPILVTTFVAE -GTAPAKDIEAVFADVGKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4BK38_BACTU -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGLPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEVTYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus subtilis TaxID=1423 RepID=A0A5F2KNH9_BACIU -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNEVMHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALASDLKAFTVDNTLTTDQRT -ILTDWMRGNATGDELIRAGAPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0005C9B5B8 -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNEVMHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALASDLKAFTVDNTLTTDQRT -ILTDWMRGNATGDELIRAGAPTGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FMQ74 TaxID=1913579 RepID=A0A1J5X4Q9_9BACI -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTNAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001145FF19 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDA28B4 --dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLASGMVLARVD -KGEENLERRVTYDQDKIVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLESLGGP -EALTKWLRSIGDTSTRLDRIETALNEAKKDDPRDTTTPDAMLDTLGNLTIGSVLSEPSRT -QLIDWMVANTTGAARLRAGLPEEWKIGDKTGTGNNGSAADIAVLWPESGSPILVATYIAE -ATAPVSELNEVFAEVAKIAA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RHB7_9BACT ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQGLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLPAFLRQMGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00061C387F -----NKKFLQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKIVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis acidicola TaxID=2596893 RepID=A0A5N0URZ0_9PSEU ------QDFQQLEATFGARLGVYAVDTGTGRTV-TYRADERFPFASTYKALAAGAVLQREP ---LEELDRKITYGSGDLVNYSPVTEKHVADGMSLRDVMDAALRYSDNTAGNLLFAELGGP -AGFTAAMRALGDTTTQSDRRETELNEGTPGDLRDTSTPRALADDLRAFGVGNALPDNKKK -VLLDFMRANTTGGELIRAGVPQGWQVADKTGNASYATRNDIAVVWPPQGAPIVVAILSTK -PAKDAGYDNKLIAQAASTALGSf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=G9Q733_9BACI --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B4LD20_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKGDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMEDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPNGWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIEEAAKVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0003A4AB70 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNG -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001143864B --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKDDLVEYSPFTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPTRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FMQ74 TaxID=1913579 RepID=UPI0009F2CB42 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTNAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus TaxID=1386 RepID=UPI0011449304 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. Cedars TaxID=1980674 RepID=UPI0011653064 -------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS ---MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP -DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT -LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPIVIAILSSR -DTPDATYNDALIAQAAKVALD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI00111BF330 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7BHS8_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces iakyrus TaxID=68219 RepID=UPI00068B26E4 -----TARLRELEQEHTARLGVYARNMRTGRTV-TYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPVTEDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSIGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALERRDRA -RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000D73C620 -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKNDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 112mf TaxID=1761752 RepID=A0A1H4G6G2_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHADTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011452478 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKTLAAGVLLQQNS ---IDTLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=5 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1D3PIK5_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. DSL-17 TaxID=2567941 RepID=A0A4S4BHX3_9BACI ---ATNHDFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYVSTHKALAVGALLQQKS ---IEDLNQRITYTREDLVNYNPITEKYVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -AGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DKKDADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF1BF18 -----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=B5UTC4_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=15 Tax=Bacillus TaxID=1386 RepID=A0A2B8W8Q1_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFDC1F4 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELGDASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFMLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFCD031 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDNRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus arenosus TaxID=1229153 RepID=A0A3D8PI95_9BACI ---SADNEFAKLEETFDARLGVYAIDTGSGQVI-SYQEDERFAYTSTFKALASGALLQKNE ---IEDLNKVITYTEDELITYSPVTEKHVDTGMTLREIIEAAVRYSDNTAGNLLLNELGGP -EGFEEALREIGDEVTEADRFEPTLNTAVPGDSQDTSTPKAVATSLKEFAVSDLLSEEKRA -IFNDWLSGNATGDKLIRAGVPDDWKVGDKSGAGGYGTRNDIAVIWPPDREPIVIAILSSR -DTEDATYDDALIAEAAKVVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000A35B941 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN) TaxID=398527 RepID=B2TE74_PARPJ ---AIRRRLAEIEAASGGRLGVSIVDTMSGVHA-GLRTDERFPMCSTFKILVAGAVLARTD -RGEESLQRRVVFSLSDVVSNSPATSKHTRELMSVAELCKAAITLSDNTAANLLLSTFGGP -AGLTAFARSLGDRVTRLDRIEPALNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGDAARSNTAIADVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000F095C3D -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=A0A1W6Z5S5_9BORD -----HAACARLERAHDRRLGLYAIDTGNGRTV-GYRAGERFAFCSTFKALLAGAILARLK -ADAGILDRRILYTRHDLVPYSPITEKHAGGSMTVADLCAAALQYSDNTAANLLLHAVGGP -AALTGYARALGNRSFRLDRYEPALNSAIPGDPRDTVTPADMAASLRSLAVGNALTAGGRE -RLPEWLLGNTTGANRIQAGAPAGWRVGDKTGTGDYGAANDIAIVWAPDRPPIVLAVYTAA -SATAAAADEPLIAAATQLAI--- ->[subseq from] UPI00143B069D UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143B069D ----AVQRLSDLERTFDGRLGVFAFDMGSGASL-AWRSEERFPVCSTFKAFLAAAILHRST -SDAGLLDRVISYPLEELVFHSPVAQQHVHSGMSVRDMCAAAIQYSDNTAANLLMRILGGP -DAVTAFMRQTGDMGFRLDRWETDLNTAIPGDPRDTSTPVAMSRSLDRLLFGDVLSDTHRA -VLQDWLKGNTTGASRIRAGVPEGWMVGDKTGSGSYGTANAIGVLWPPGRKPVIVSIYTTQ -HYRGAVWRDDIVAQATRIIV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A443TGC9_BACMY -----NHSFVKLEKEYDAKLGIYALNTGTNQTV-TYRSDERFAYASIHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKAIATSLQDYALGDILSTEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudomonas TaxID=2583993 RepID=UPI0013784745 --eSLEQKLSALEKRANGRIGMALIESGSQRML-TYRGDERFAMASTFKALLAGAVLQKSV -GQPGLLSKRVTYDKASLVVYSPVTEQHLEEGMTVSELCKAAVEWSDNSAANLLLKELGGP -ASVTQLAMSLGDDKTRLDRWEPELNSAIPGDERDTSTPLSMARNLLKLTVADGLPKEQQQ -LLVSWLKDSKTGAQSIRAGVPGGWPVGDKTGAGEYGTTNDLAIIWPPTGQPLVLAIYFTQ -REQKAQARRDVLASVSKMVLAEf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD5A1E ---DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVSRIVT--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8Z8T7_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002799638 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRFSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium fabae TaxID=573179 RepID=UPI000F861254 --dDIQRRLAALEKRTGGRLGVSVLDTQTSISF-NYRGSEAFPMCSTFKALAAGFVLARVD -KGEENLQRRVSYGKDKLVDYSPLSEKHAGADMTIAELCEAAVTVSDNTAANLLLESFGGP -PVLTDWLRSIGDGTTRLDRTEPTLNEGRKDDPRDTTTPDAMLDTLGNLTLGSILTEASCD -RLIAWLVASTTGKERLRAGLPQDWKIGDKTGTGPNGSLGNIAVIWPPDRGPIVAAVYIGE -ATVPVKELNPVFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110FEE2D ------RELKALERKFDARLGVYAVDTGTGREV-AYNDRERFAYASTFKALAAGAVLRTYT ---LSGMNQVVTYSEDDLIAHSPVTEKHVGTGMTLRELCDAAVRFSDNAAANLLLDALGGP -KGLDAHLARMGDDVIRMERREPELSRWAPGDTRDTSTPRAMAEDLRAFVLGDVLGKDERA -QLTTWLRTNTTGDETIRAGMPEGWVVGDKTGTGGYGARNDIAVVWPPGSAPIVVAIMSNR -DEEDAGHDNRLIAQAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4BA139 -----NDSFAKLEKEFDAKLGIYALDNDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=2 Tax=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442) TaxID=644283 RepID=D9TA79_MICAI -------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. NH11B TaxID=1866314 RepID=UPI0009214375 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVGTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009E25156 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus swezeyi TaxID=1925020 RepID=A0A5M8RG66_9BACI ---EVKHHFTKLEDQFDARLGVYALDTGTNQTV-TYRSDERFAFASTLKALAVGALLQQKS ---IKDLNQNITYTHDDLVSYSPITEKHADTGMTLKELSDAALRYSDNTAMNLILQQLDGP -KGLKKALRKIGDHVTNPTRFETELNDVQPGETRDTSTPRALAASLQAFTLGDALPIEKRE -LLIDWMKRNTTGDSLIRAGVPKGWEVADKTGAASYGTRNDIAIIFPPNRCPIVLAILSSR -DKKDAEYNDELIAEATKDVINAf ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011A4460A --tEMKDDFAKLEEQFDAKLGIFALDTGTNQTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITENHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus niacini TaxID=86668 RepID=UPI00052FBCEB ---HIHREFGELESKFDARLGVYAIDTGTNQTV-SYRSHERFAYASTYKALAAGALLQQYS ---IDQLEELVTYNSEDIVSYSPVTELHVDTGMTLGEVIEAAVRYSDNTAGNLLLEKLGGP -EGFETALRQIGDKVTEADRYETDLNSAIPGDTRDTSTPKSLATSLKAFAVSDLLPTEKRK -ILTDWMRGNATGDALIRSGAPTGWEVADKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYNNTLIAEAAKVALN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009BCFA2F --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5410A -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKAS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRTGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora carbonacea TaxID=47853 RepID=UPI0009F312ED -------ELVALERRFDARLGVYAVDTGTGRTL-AYRADERFAYASTIKALAAGALLARTS ---EAELDRVVRYDRADLVPHSPVTQRHVSDGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPTRTETSLNEAAPGDVRDTSTPRALAGSLRAYALGDVLSPADRG -VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDGAPVVLAVLSRR -DAKDAQPDDALIAEAARVALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FDA1_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRGLCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 196mf TaxID=1761754 RepID=A0A2V4X4A6_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BF2E407 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. (strain JS666 / ATCC BAA-500) TaxID=296591 RepID=A0A1G9VW27_POLSJ ---SVTRRLVAIEKTSGGRLGVSMLDTGSGAKY-GYRAGERFPMCSTFKLLAAALVLHRVD -SGQEQLGRRIPIAAGDILPHSPTTQQHIGPQLPMAALCEASIIVSDNAAANLMLASFGGP -AGLTAYLRGLGDKMTRLDRTEPELNESAPGDVRDTTTPDAMLATVHKLTLGSALSDASRQ -LLVQWLQANTTGDRRLRALLPPGWRVGDKTGSGARGSTNDVGLIWPPGGAPLLVAAYLTG -TKQPAAQRDAALAQVGQLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEE430C -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. RV43 TaxID=1661387 RepID=UPI00064C4197 -------ELAALERRSGARIGVYALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARAAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-4489 TaxID=1609095 RepID=A0A0X3V2K1_9ACTN ---SLDSHLSDLEHRYGARLGVYARNVRTGQVI-AHRAQERFAMCSTFKAIAAAAVLRDQA --HCAPMDKVIHYPPTDILPNSPRTEEHVDTGMAVRDLCGAAIQYSDNTAGNLLLRQIGGP -GGLTAFLRSIGDPVTRLDRWEPDLNTAIPGDLRDTTTPEAICRSYEQLTLGRALTAPDRE -RLVAWLKGNTTSDERFRAGLPHTWTVADKTGTGSYASANDIGVAWTTRHTPIVLAVLSTK -PTKDAPVDNALVADAARVIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. C11 TaxID=1178594 RepID=UPI00140BD4E3 ---HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPHDRFAYASTYKALAAGALLQHYS ---IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -EGFETALRQIGDNVTQVDRYEPDLNSALPGDTRDTSTPKSLATSLKAYAVSDLLSIEKRK -ILTDWMRGNTTGDALIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNTLIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora carbonacea TaxID=47853 RepID=A0A1C4VS08_9ACTN -------ELVALERRFDARLGVYAVDTGTGRTL-AYRADERFAYASTIKALAAGALLARTS ---EAELDRVVRYDRADLVPHSPVTQRHVSDGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPTRTETSLNEAAPGDVRDTSTPRALAGSLRAYALGDVLSPADRG -VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPDGAPVVLAVLSRR -DAKDAQPDDALIAEAARVALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8V0_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLRGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0013D7D356 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFKKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNG -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRRLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSEAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAER-------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000E2E7889 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF616A1 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILIEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000BA9E42D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase KPC-34 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1C8FRX1_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5A2F9 ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKTLATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase CRH-3 n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2R2V0K8_9NEIS -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -DKPGLLDKRIRYSKTALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTAFMRSIGDARFRLDRLEPELNSAIPGDPRDTSTPKAVAESAQKLALGKALPEPQRQ -RLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium carotovorum TaxID=554 RepID=UPI000B96F99A --pDTLDTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFDQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP -QELTIFLRKTGDHVTRLDRWETALNEALPGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -GQATIEERNKQIAEIGTSLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas floridensis TaxID=1843580 RepID=A0A1A9M5L7_9XANT ---MLRAQWAEIERGTGGRLGISLLDSATGWRL-GQRQNERFPMCSTFKFVLAAAVLQRVD -ESRLTLAQPVKIRASDMLEHAPVTKRHVGSALSVGELCQATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000DC1EE66 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEELNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKIVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium americanum TaxID=194963 RepID=A0A4R2BXJ4_9RHIZ ---DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARFD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGDMTVAELCDAAVTISDNAAANLLLESFGGP -AGLTSWLRSIGDRTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR -QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE -AKVEPAELNPVFAEVGKIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FB19_ECOLX ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATRDER--------------- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT68W TaxID=2654255 RepID=UPI0012655229 ---AAQAQLAALEHAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQHLRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAYARSIGNTVFQLERWETELNSAIPGDVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis HD-771 TaxID=1218175 RepID=J3ZWJ7_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Roseovarius tolerans TaxID=74031 RepID=A0A0L6CX15_9RHOB --dALRQTVQDVEARIGGRIGYAVTDLNSGQEW-GSRPDERFPMSSTFKALLCGVILARVD -AGAEALDRRITFGRDDLVTYSPVTDRHLGTGMTVGELCRAAITMSDNTAGNLLLATIGGP -EGFTETLRDMGDATTRLDRWETALNEGAPGDERDTTTPRAALSTLQALLFGDMLTAASRQ -QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPTPNHPALVTIFMTG -ADADMTDRNAAIAEIGAAIFA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-9 TaxID=1053204 RepID=R8DAZ4_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF3B19E ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP -KELTAFMHNMGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia amamiensis TaxID=404578 RepID=UPI00083021A3 ------ASFLEMETNHAARLGVYAIDTASGHTV-AYRDGERFPMASTFKGLACGALLRDHP -LSTGYFDQVIHYPRTDLVEYSPVTEKHVDTGMTVAELCDAAITVSDNTAGNQLLKLLGGP -AGFTAFLRSIGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLGEPERE -RLKSWLIANTTGGKRIRAGLPAGWTVGDKTGSPAYGSALDVAIAWPPGRGPLVIAVLSTK -FEQNAQADNPLVADAARAAVE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF4EC26 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP -KELTAFMHNIGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY3_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWRKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDG------------------ ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. FSL R5-808 TaxID=1227076 RepID=W4B529_9BACL -------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS ---MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP -DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT -LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPIVIAILSSR -DTPDATYDDALIAQAAKVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar guiyangiensis TaxID=180871 RepID=A0A242XKJ5_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFTFASTSKSLAVGALLHKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A1N7EDQ1_9BACI -----NHAFAKLEEKFDAKLGVFALDTGTNQTV-AYHPDERFAYASTHKALAVGALLQQKS ---IEDLNQRITYTPEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDISIIWPSKGDPIVLAVLSSR -DKKDADYNDDLIAETTKEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. H-KF8 TaxID=1727216 RepID=A0A1A5P2G9_9ACTN ----ATGDFEELERTYGARLGVYAVDTGSGREV-AHNDDERFAYASTFKAFAAAAVLREHS ---PSGMDEVITYSGDDLVAHSPVTEKHVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP -KGLASALEEVGDTVTRVERREPELNQWAPGSTRDTTTPRAWAGDLRAFVLGDALDGKERA -QLTKWLRTNTTGDELIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR -RTADAGHDDELIAEAASVVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI00042F1B34 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YM21_9BACT ---DFANRILPIEERAGARIGVAALDTGTGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD -EGKENLERFIRYSSQDLLEYAPVTKAHLKDGMTLAALCAAAIEQSDNTAGNLLLDVIGGP -SGLTNFARSIGDQITGLDRKEPELNSAIPGDERDTTTPAAMCADLQRLLLADVLFESSRQ -EFEDWLRHNETGALMIRAGVPQTWSVGDKTGRCANGATNDIAILRPAGRAPILIAIYCIG -STAPADDRAAAIAETARAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora chalcea TaxID=1874 RepID=A0A365V128_MICCH -------ELAALERRSGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVAERHVETGMTLRDAAEAAVQYSDNTAGNLLFDALGGP -AGFARALREVGDQVTRPVRTEPELNAATPGDERDTSTPRALAGSLRAYALGETLRPADRD -LLLGWMRASTTGSGLVRAGVPAGWPVADKSGTGGYGTRNDIAVVWPPDGAPIVLAVMTSR -DSRDAKPDDALVAQAARATVTAf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001145488F --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B6MYI9_9BACI -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00123778E7 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI000F02F8E6 -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEWFAYASTYKVLAAAAVLKTSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLHQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALANDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. ABP14 TaxID=1892404 RepID=UPI0011A666E7 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=B8ZHX8_KLEOX ---AIQQKLTNLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVLNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001145393B --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVNYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus anthracis TaxID=1392 RepID=A0A2A7DBQ6_BACAN -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFC433 ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWMVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFAEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4Z662_9PSEU ------DRLVELERKFDARLGLYALDTGTGATI-AHRADERFAFCSTFKALAAAAVLHRNP ---LPHLDEVITYTESDLMKSAVITGQHVDTGMTIRELCEAAVRYSDGTAGNLLLRDLGGP -AELTAYARSLGDAVTRMDRFEPDIVEATPGDPRDTTSPRAFGATFQKIVLGDALPAEKRA -FLRGLLERNTTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAVVWPPNAPPLVLAIMSSK -ATKDAEYDQALIAEAAAHVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BED89C9 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429DAP0_9PSEU ---QFHDRLMELEKKFDARLGVYALDTEGGSTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVRYSREDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD -FLRDLLQRNATGAERIRAGLPPGWTVADKTGTGDYGTLNDIAVLWPPAKAPIVLAIMSSK -AAKDAPYDQALLAEAAKYVAETf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00114522CB --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62415 TaxID=2182390 RepID=UPI000F8E202A ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWNIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=C3DK16_BACTS --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62409 TaxID=2182388 RepID=UPI000F8D2887 ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWNIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Hydrogenovibrio marinus TaxID=28885 RepID=A0A066ZN74_HYDMR ---NFKQQISELESTFGGRLGVAVWDASSGFQL-QYRGNERFAMCSTFKFLLAASVLAKVD -AKEESLNRVVTYSTSDLLDYAPITRKNLRNGMTISQLLAAALQYSDNTAANLLFEPVRGP -QGLTTFMRSFGDKETRVDRIEPHLNTNIPGDERDTTTPNAMLKSMKKILLGHVLSEASKN -QLTQWMLNNTTGANKLRAGIPTYWPVGDKTGSGNNGAMNDIAIMWPDADDPILVAVYYTG -SKEPFETKNHVLEQVGRIISQQf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-37 TaxID=1463903 RepID=UPI0004CC37E7 -------SLTDLEREYGARLGVYALATGTGATV-VHRADERFALCSTFKTLAAAAVLDRHP ---VPRLDRRVTYTRADLITYSPVTEKHVDTGMSLRDLCDAAVRYSDNTAANLLLREIGGP -RALTAHLRGLGDRVSRLDHTEPGLNGNPPGDPRDTTSPRAVAADYRALVLGDALPAAKRE -LLADWLVRNTTGDLRVRAGVPRDWKAGDKTGTGEWGRANDVAVLWPPHGAPLVIAVLTER -PDREAAASDALVAEATRRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=A0A4Q0X7G8_9BACI --qATHKEFSQLEKKYDARLGVYAFDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALIQMSDRVTMSDRFETELNEAMPGDNRDTSTAKAIATNLKAFTVGNALPNHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium sp. CCBAU 05631 TaxID=794846 RepID=A0A249NQD7_9RHIZ ---DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGNMTVAELCDAAVTISDNAAANLMLESFGGP -AGLTSWLRSIGDGTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR -QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE -AKVEPAELNPLFAEVGKIVA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1E021 ---AMYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Sinorhizobium TaxID=28105 RepID=A0A2S3YHF7_9RHIZ ---DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGNMTVAELCDAAVTISDNAAANLMLESFGGP -AGLTSWLRSIGDGTTRLDRTEPDLNEAKFGDPRDTTTPVAMLETIGKLAFGSVLAESSRR -QLVEWMVANTTGDARLRAGLPKDWQIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE -AKVEPAELNPLFAEVGKIVA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1FBC7 ---AMYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C4FPZ3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDNRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C4Q8T3_9BACI -----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPTEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=Q737V7_BACC1 --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAIYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8MUT7_9BACI ---AMYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D9VBM3_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRARVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 8989 TaxID=1591156 RepID=UPI00136D4DA1 --qTLQQRLAEIERRSGGRLGVSLLD-GSGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRLPVRKADLLAYAPVSERHVGGALSVAELCQAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDAQTRLDRNEPSMNDVVAGDLRDTTTPAAMAATMRTLLLGEALQPASRQ -RLIAWMRDNRTGNDCLRAGLPAAWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDAALKAVAQAVVA-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A4V2VJD4_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDASTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Marinactinospora thermotolerans DSM 45154 TaxID=1122192 RepID=A0A1T4SZX3_9ACTN -----AGDFERLEGEFDARLGVYAIDTGSGETV-THRADERFAYASTIKALQVGAVLQQNT ---LEEMEEVVTYDEEDLVTYSPITEQHVDTGMTLREVSDAAVRYSDNTAANLLFEELGGP -AALDAALEGIGDDVAEVVRIEPELNATAPGDTRDTSTPRAMADSLRAYALGDVLPADERA -VLTDMLKGNTTGDALIRAGVPDDWEVGDKTGAADYGTRNDIAILWPPDEDPIVVAVMSDK -DTPDAEYDDALIAEAAQVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A3A2YK26_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRKMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGNKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus paramycoides TaxID=2026194 RepID=A0A1J9UNB7_9BACI --------FVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELVDASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAEYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679GZC0_9BACI -----DDSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKTIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKKDAEYDDKLIADATKTVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1B2VWE5_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERN-------------- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A150EQV6_BACCE --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAIYDNQLIKEAAEVVID-- ->[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Duganella phyllosphaerae TaxID=762836 RepID=A0A1E7WVQ3_9BURK -----AAQLARLESEAKGRLGVAAINTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP ----SLLDRRIRYTAADLVSHSPVTQQNLADGMTVAELCAATIQTSDNAAANLLMKQIRGP -AGVTAYARSIGDKVFRLDRWETELNSAIPGDPRDTTTPLAMMKSLQSVTLGPALTVDKRK -LMTQWLVGTTTGDTRIRAGVPYDWQVGDKTGTGAYGTTIDIGVVWPTGKAPVVMALYFTQ -PGQGDKANSEILAAAARVVVEAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar pingluonsis TaxID=180881 RepID=A0A243BB67_BACTU ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGETHDTSTSKALATSLQAFALGDVLSTEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia shimofusensis TaxID=228596 RepID=UPI000A00AB84 -------RFADLESTSGARLGVFAVDTGTGRVV-THREHERFPMASTFKALACGALLRDHP -LSSGYFDQVIHYAAGELVEYSPVTERHVESGMTVAQLCDAAITVSDNTAGNQLLKLLGGP -AGFTAFLRSLGDDTSRLDRWETELNSAIPGDERDSTTPAALAADYRALVVGDTLAEPERA -RLTSWLVANTTGDARIRAGLPADWTVGDKTGSPAYGSALDVAVAWPQGRAPIVIAVLSTK -SEPDAEADNALVAAAARAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110FF26C ------RELKALERKFDARLGVYAVDTGTGREV-AYNDGERFAYASTFKALAAGAVLRTYT ---LSGMNQVVTYSEDDLIAHSPVTEKHVGTGMTLRELCDAAVRFSDNAAANLLLDALGGP -KGLDAHLARMGDDVIRMERREPELSRWAPGDTRDTSTPRAMAEDLRAFVLGDVLGKDERA -QLTTWLRTNTTGDETIRAGMPEGWVVGDKTGTGGYGARNDIGVVWPPGSAPIVVAIMSNR -DEEDAGHDNRLIAQAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YR295 TaxID=1500257 RepID=UPI00055C64E8 --nDIEKQLAALEKRTGGRLGVFVLDTSTNVSF-GRRQDERFAMCSTFKALAAAFALARAD -KGEEKLDRRIPVLKKDLLSYSPVVEKHVGGGMTVRELCDAAVTYSDNAAANLLLASFGGP -KGLTTWLRSIGDETTRLDRTEPELNEAKIGDPRDTTTPMAMTETLGRLLLQDVLSPSSRD -QFTAWLVANATGDRRLRAGLPQDWMIGEKTGTSGRGEAGDIGFMRPRDGHTILASVYIAE -GKKPTKELEPVFADVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI00045D1844 -----NEKFAEIEKEYNARLGVYAIDTGTNQRV-QYNSDDRFAYASTFKVLASAILLKQNS ---IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELEGP -EQFKQALRDLGDDVTQPERFETELNDFAPGKKRDTSTPKAMANTLKKVALDDFLPDDKRE -LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH -EEEDAEYDDALIAKAAEIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0002E9CB85 ----ITKKFVQLEQKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKVLAAAAVLKKNP ---IEKLNEMIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFENSLKQIGDQVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTADKRT -ILTDWMRENATGDELIRAGTPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYDNALIAEAAKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillaceae bacterium GAS479 TaxID=1882832 RepID=UPI000B82E9B7 ---AFRRSFVQLEEKYGARLGVYAIETGTGRSI-AHRPDERFAYASTYKALAAGFVLKHST ---ANELERVITYSKDDLVSYSPVTELHVNTGMTLKQLCEAAVRYSDNTAGNLLFKQLGGP -KGYEVALREIGDVVTQVDRLEPELNEAVPDDTRDTSTPRALATILSNFTVGDVLADDKRS -ILMDWMSGNATGDELIRAGVSEDWKVADKSGAGSYGTRNDIAVVWPPSGAPVVIVIMSSR -DEQNADYDNALIAEAAKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE0645 ---DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVSRIVT--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A5S4JEZ3_STRGR ------AAFRKLEREFGARLGVYAVDTGTGREV-THNDRERFAYNSTFKALQAGVVLSTYS ---LEGMDERVAYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -AGLDAALEKLGDDVTRMDREEPELSRWTPGEERDTSTPRALAGDLRSLVLGDALPAPERK -QLTAWLRTNTTGDAVIRAGVPDNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -STKDAEPADELIAEAASAVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD94499 ---DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVSRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCA22 ---DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVSRIVT--- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. W64 TaxID=1735583 RepID=UPI0007B25FAE ------DTVGQLEDEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD -RGEESLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGAGHNGSRGIIGVIWPETGKPYLAAAYMTG -SDASFKQRNAVIAEIGKAMIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Nocardia mangyaensis TaxID=2213200 RepID=A0A1J0W304_9NOCA ------PSFADLESEYGVRLGLSVVDTGTNTAV-DHRADERFPIASMFKGIACGALLQAHP -LDTGYFDKVIHYTADDLVEYSPETEQHVETGMTVAELCHAAITVSDNTAGNLLLRELGGP -EGFTAFVRTLGDTVTRLDRWETELNTAIPGDERDTTTAAAIAADYRALVLGTALPAPERA -QLADWLRANTTGGERIQAGVPADWTVGDKTGTPAYGTALDVAIAWPPGREPIVLAVLSTK -SERDTDPSNESIAEATRLAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B6D9F5_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=7 Tax=Bacillus TaxID=1386 RepID=A0A2B9EAU7_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPVIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=A0A4R0XEZ0_9BURK ---ALEKQLAQIEAQTGGRMGVAILDTASAKPQ-GWRMHERFPMCSTFKFLLASAVLVRKD -QGKDQLERKIVYSKDVVVANSPVSGPRAGSDMTVAELCEAAITRSDNTAANLLLDSIGGP -AALTAFARGIGDRITRLDRNEPTLNEALEADPHDTTTPAALLADMRALLLGEHLSTASRE -QLTAWLAANKTGDTRLRAGLPKAWRIGDKTGTGERGTSNDIAVIWPEGRAPILVVAYLTG -ATATSTQRDAAIAQVGALVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002799AE4 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=A0ESF8_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTVGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQQFAR--------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides (strain KBAB4) TaxID=315730 RepID=A9VH74_BACMK -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8ECC7_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQAI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LETLDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A243E9D3_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A5P9Y4L0_BACCE -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKRA---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000EA0284F -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKRA---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2V2H5P5_BACTU -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYQSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKTPIVLAILSNH -DKEDAKYDDKLIADATKTVLN-- ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H4ZHI0_9ACTN ---DAHAALRRLERANRARVGAYAHNTVTGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD -HHGETLARRVHYTDADLVANSPVTGKHLATGMTIAELCAAALQRSDNTAANLLLRALGGP -TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIARTYTRLLLGDALTPADRA -RLTAWMKANETNTDRFRAALPRDWTLADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGK -AQQAATPDDPLVADVTRVLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. KC606 TaxID=2530379 RepID=A0A4R4TZF8_9ACTN ------PDFTALERRFDATLGVYAADTGTGRTL-AHRADERFAYASTFKALAAGALLDVTS ---DAELDRVVRYGREDLVTYSPITEKHVGAGMTLRAIADAAVRYSDNTAANLILAELDGP -DGFERKLREIGDTVTDPARIETTLNEAAPGDVRDTSTPRAMATSLRAYALGDALSGADRA -ILVGWLRRNTTGAKMIRAGVPADWQVGDKTGSGGYGTRNDIAVLWPPQGAPIVLAVMSRR -DTKDAAYDDALIAEAAKLVV--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000FD6DA17 --qATHKEFSQLEKKFNARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPVIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5T8K8_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRHIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0014312B47 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTNKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011558F52 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPAEKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPVIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. COPE52 TaxID=2233998 RepID=A0A345XHN8_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEEHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI001155F3FE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEEHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=UPI0009E76DB6 -------EWARLETSVGGRLGVAVLDTATGHCS-GHRVDERFPMCSTFKWLAAAVVLQRVD -AGVERLDRALPVAAHDIIDHSPVTVTRVGGTITLGELCEATITVSDNAAANLILAACGDP -AAVTAYARSVGDTVTRLDRNEPSLNEARPGDPRDTTTPAAMAATLNKVVLGDALTRASRE -RLAGWMRGTKTSGDRLRVHLPAGWRLGDKTGSGANGTTNDVGVVWVPGRAPVVVAMYLTE -AGASPAARNAVIAEAGRVVWT-- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas rosea TaxID=198092 RepID=A0A1M6JZ34_9PROT ----LPEAFRRIEAARGGRLGVAVLDAGSGRGA-GYRAAERFPLGSTFKLLVAAAVLARAD -AGRESMERRIRFTREDLVTYSPVTQRAVGGEMTLAALCEATMVTSDNTAGNLLLRVVGGP -EGLTAWLRGLGDGVTRLDRWETALNEARPGDERDTTSPAAMLASLRAVTVGNALSEAARA -QLIGWLRGNRTGDARLRARLPAGWQAGEKTGTSAHGTSNDVGLLWPPGDAPVLVAAYLTE -GAADGAVRDAALAEVGAAVAAAw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4U3A2T3_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITGKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFC43F1 ---ATYKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNMLFHKIGGP -KGYEKALRKNGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNGLPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sediminicola TaxID=946078 RepID=A0A1A9BA46_9ACTN -----DRAFRHLEETFDARLGVYAIDTGTGATV-GYRADERFAYASTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITEKHVADGMTLRALADAAVRYSDNTAGNLLLRRLGGP -QRFEKELRGVGDKVTAPARYETALNEALPGDRRDTSTARALAQDLRAYAVGDSLDPADRD -ILNGWLRGNTTGGELIRAGVPDGWVVGDKTGSGGYGTRNDIAVVWPPDRAPIVLAVLSSR -DQKDADYDNALIARAAEVAI--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Hyphomicrobium TaxID=2619925 RepID=UPI0012DD3875 ------NAFAGLEKQYGGRLGVAVVDTGSGERM-AYRADERFPMCSTFKLLIVGAVLHNVD -KGSERLDRWIPFQASDLLDYAPVTKTAVGNGMTMSDLCAAAIEYGDNTAANLILKAVGGP -DGATRYVRSLGDEVTRIDRFEPDANTCIPGDPRDTTTPAAMLADLKALVLGDALSANART -QLLGWLNGCKTAARRIPADLPAGWISGDKTGSGANGTANDVAIIQRPNKKPLLVAAYSTG -VAAKPADRDPMLADVGRIVARHf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A090ZAE1_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIATTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 01529 TaxID=2203205 RepID=A0A3Q8V861_9ACTN ---DARRRLRELEKGYPGRIGLHALNTGTGATL-GYRADERFAIASTFKVLAAAAILRRAR -EEPGLLDVLVRYGRDDLVTYSPRCEMHLPTGMTVRELCDATVTYSDNAAGNLLLRRLGGP -SGITEFARSLGDSRTRLDRWETDLNTNIPGDPRDTTTPAAMTANLRKLVLGDALAAPDRD -QLVRWLVENTTGDARIRAGLPEGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVISVYTTR -LDPDTPGEDRIAADMTRIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Erwinia amylovora TaxID=552 RepID=Q8GEF8_ERWAM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGX -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTXMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVXYPTG -SQATMDERNRQIAEIGA------ ->[subseq from] Beta-lactamase n=1 Tax=Acidobacterium capsulatum (strain ATCC 51196 / DSM 11244 / JCM 7670 / NBRC 15755 / NCIMB 13165 / 161) TaxID=240015 RepID=C1F6V5_ACIC5 ---AFEDALAHLERSSGGRLGVALWQPATSLRA-GHRLHQRFPMCSTFKVMLVAAVLHRAD -QADGHLDRRLHYTQAQVLSWAPVTSKHVATGLTVRELCAAAITLSDNTAANLLLASLGGP -AAVTAYARTLGDTRTRLDRTEPTLNSAIPGDPRDTTTPSAMAHNLDRLLLGNALSPASRR -QLTAWMLDCQTGLHQLRAGLPAACKVADKTGNGSHGTSNDIAVLWPPHGAPVIITAYLTQ -STLTYSEQNAVLARVGRAA---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000CB18BD7 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=J8Z0E1_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8ZW82_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLHKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007FB598F -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRIKYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 123MFChir2 TaxID=1169144 RepID=UPI0012DCC85D ---TTMEKFEQLEKEYDARLGVFALDTGTKQTV-TYHPDERFAYASTHKALAVGALLQQKA ---IEDLDQRITYTREDLVNYSPITEKHVDTGMTLKELCDASLRYSDNTAGNLILKQLGGP -TGFKKELEEIRDNITNPERFEPYLNEVNPGETHDTSTPRALATSLQAFTLKDTLSTEKRE -LLIDWMKRNTTGGALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAILSSR -DKKDADYNDKLIAEATAEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B4UAM0_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE09955 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEYFPLCSTYKALAVGFVLARVD -QGTEKLDRRVTYGKDKVVTYSPETEKHADGDMTIAELCAAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDIETRLDRNEPDVNQAVKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAAAKDVEAVFAEVSKIIVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. AcE210 TaxID=2292703 RepID=A0A371XSB6_9ACTN ----ARRRLRALEAGYPGRIGVHALHTGTGAVL-AYRAQERFAIASTFKVLAASAILHRAR -EEPGLLDVLIRYGRDDLVAASPRTELHLETGMTVRELCDAAITYSDNTAANLLMRRIGGP -AGVTAFARSLGDSVTRLDRWETDLNTNLPGDRRDTTTPAAMTEDLRALVLGDALHPLDRG -QLTRWLVENTTGDKRIRAGLPPGWRVGDKTGSPAYGGVNDVAVAWPPGGAPLVVSVYTTR -LDPDTPGEDRIAADITRVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1N6VBJ2_BACCE -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -STFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSKKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Gallaecimonas pentaromativorans TaxID=584787 RepID=UPI00067EDE25 ---DFSRTISDIESQYGGRLGVAAFDSRDGRQL-GYREHDTFAMCSTFKALLAAAVLKKAE -QGQLSLDTELSYGKGDLLDYAPVTAAHVDEGMTVSALADAAITLSDNTAANLLLAKIGGP -AGLTAYIRSLGDNLTRLDRTEPSLNTNLPGDPRDSTTPTAMVALWQKLLLGKALAPASRQ -QLLAWLKATQTGMAKIRAGLPGGWQAGDKTGSCENGGSNDVAIVWPSGQPPYLLAVYYSD -GLGGSAQKNAAIAAVSQAVAEQf ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A2B6LWT0_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A2B5PXK7_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=J9ASZ6_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEBC295 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C4AWZ8_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFBFDBD -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000A27C5F7 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI0011A1BBB5 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Wb2n-11 TaxID=1030533 RepID=UPI000AE222E2 ----FTRDFKELERKFDARLGVYAVDTGTGREM-AYNDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVITYSRDDLAAHSPVTGKHVGTGMTLRALCDAAVRFSDNTAANLLLDQLGGP -HGLDAVLEEIGDDVTRMERREPELNQWAPGATRDTSTPRALADDLRAFVLGDVLGKGERA -QLTKWLRTNTTGSELIRAGVPGGWVVGDKTGAGGYGTRNDIAVVWPPDTAPIVVAIMSNR -GEEDADYDNELIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEB7E4C -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus proteolyticus TaxID=2026192 RepID=UPI0008FE7A78 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007AB89AD -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BECC089 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=9 Tax=Bacillus TaxID=1386 RepID=A0A150BZR0_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0004DD410E -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0010C3201F -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_8 TaxID=1969377 RepID=A0A328L755_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKHLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BDRD-ST196 TaxID=526976 RepID=C2SG64_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=K0FPJ7_BACTU -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELMDASIRYSDNTAQNLILTQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A377QE36_9BURK ---TAQTQLAALEQAAGGRLGVAAWRQGSELRI-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAPQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. BJB426 TaxID=2048010 RepID=A0A2G3LBB9_9BURK ---AAQTQLAALEQAAGGRLGVAAWRQGSELRL-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPASQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGIAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000D52C6AB -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALSNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWQPDRAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC2B4E ---ATYQEFFQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. ALI-22-I TaxID=1933778 RepID=A0A1V2QTN0_9PSEU -----SSDFSGLEAEFDARLGVYALDTGSGRAI-EHRADERFAFCSTFKALASAALLRRTE ---PADLDRRVTYTSADLVPNSPISGQHVAEGMTLRELMDAAIRYSDNTAANLIFNELGGP -AGFEEDLRGIGDQTTESDRIEPGLSEAVPGDTRDTTTPRAFAANLRTYVLGDVLPSDDRT -LLTEWLRNNMTGNETIRAGVPAGWVVGDKTGSGDYGTRNDIAVVWPPDGAPIVLAVMSDR -DEKEATRDNRLIARAAQTAV--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AD0117 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITFTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8C5E5_9BACL ---DADQQLGQLEKEYDARLGIYAIDTETGRTV-SYRPDERFAYTSTFKPLAAGALLLKKP ---LDGLDKVITYKKEDLVTYSPVTEKHVEKGMTLREISDAAIRYSDNTAGNLLLKELGGP -AGLETVLQEVGDHITKPERYETDLNEAVPGDIRDTSTPKALATTLKAFTVDGVLPAEKQD -VLIDWLKRNTTGDELIRAAVPEGWTVGDKTGAGSYGTRNDIAVIWPPNQAPIVMAVLSSR -TEQDATYDNALIAKAAKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0008819B32 -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SGFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000B4569A5 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura atramentaria TaxID=1990 RepID=UPI0003628776 ---SVERQLRRLEQRHHGRVGAYAIDTGTGRVL-GHRSDELFPVLSTSKAMTAAAVLRKAR -RDPGLLDRVVRYTRGDLVANSPVTEKHVGTGMTVADLCAAAITVSDNTAGNLLLRQIGGP -AGLTAFYRSLGDPVSRLDRWETDLNVWRPGERRDTTAPAAYARDLRTLTLGTALAPADRD -RLTGWMKATTTGGARIRAGLPKGWTVADKTGTGGYGTTNDVAVAWPPSGAPIVLVILTNR -RAADGAADEATVAETTAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5JXB7_9ACTN -------QLAALERRHDARLGVYALDTGSGRML-AYRADERFAYASTFKALAAGALLAATS ---DADLDRVVRYGRKDLVPHSPVTEQHVAGGMTLREIADAALRHSDNTAANLILAELGGP -DGFERALRGIGDTVTDPARTEPDLNQAAPGDVRDTSTPRALADSLQAYAIGDALSVTDQA -VLLDWLKRNTTGATLIRAAVPAGWQVADKTGAGGYGTRNDIAVVWPPDSAPIVLAVLSRR -DSRDATHDDAVIAQATRVTLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009952061 -----NQAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADNRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPETITKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -NKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=C2UVK1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W5VPU9_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMEHG--------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A172WCF6_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQP -QLLQWMVDDRVAGPLIRSVLPAGWFTADKNGTGKRCARGIVALLGPNNQAKRIVVIYLRN -TAASMAERNQQIAGIGAALI--- ->[subseq from] class A beta-lactamase n=1 Tax=Cronobacter sakazakii TaxID=28141 RepID=UPI000CFAC511 -----------------------ELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1DH22_BACCE ------HSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKSLAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKNPIILAILSNH -SKEDVNYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF92319 -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVGWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-26652 TaxID=1684141 RepID=UPI0009E993A8 ---HIDREFAQLESKFDARLGVYAIDTGKNRTV-AYRPNERFAYASTYKALAAGALLQHSS ---IDQLNELVTYNSQDIVSYSPITKLHVDTGMTLREVCEAAVRYSDNTAGNLLLKKLGGP -EGFETALRRIGDNVTRPDRYETDLNEAVPGDTRDTSTPRALATSLRAFAVSGLLPVEKRT -ILTDWMRGNATGDALIRAGAPKGWEVDDKSGAGSYGTRNDIAIVWPPHRAPIVIAILSTR -DTQNATYDNALITEAAQVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0005CF209B -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLDGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD118 TaxID=1053231 RepID=R8QI36_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRSNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0007ABB1D8 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYADKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CNZ285 TaxID=2035250 RepID=A0A4Y9V878_9ACTN ------AELAALERRFGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALREVGDSVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAKPDDALVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI000A3732BD ------EGFEKLEREFGARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLDTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAEDLRAFVLGKALRAPERA -QLTAWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D035EDA -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPTEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1E8AKW3_BACTU -----NHSFVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQDYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora haikouensis TaxID=686309 RepID=A0A0D0US04_9ACTN ------AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS ---EAELDRVVRYDRADLVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPARTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG -VLVDWLRRNTTGSTLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR -DAKDAQPDDALIAEAARVTID-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. Hp2 TaxID=701189 RepID=UPI00112A6D71 ---DLAGRWAAIERESGGRLGVMLLDTAGGRRV-GHRQDERFPMCSTFKFLLAAAVLKQVD -AGKVGLDRRLPIQASDLVGHSPATGKHVGPDLSVAEMCQATLIWSDNAAANLLYPLVGGP -AGLIAFLRGIGDATTRTDRLEPMLNEFAPGDPRDTTTPAAMAGTLQRILLGDVLRPASRR -RLTDWLIDNRTGNARLRAGLPPDWKIGDKTGSNGEDTVNDIAILWPPGRPPLLLAAYLNG -AKVDAAGQDAALRAVAQAVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE153DC ---DIDKRLAALEARIGGRLGVSVLDSQTDVSF-GYRGSEAFAMCSTFKVLAAGYVLARVD -NGDEKLDRRITFGKDKLVSYSPETEKHAGGEMTMAEICKAGITLSDNTAGNLMLESFGGP -AALTDWLRSIGDGTTRLDRMETALNEAAKGDPRDTTTPDAMLDSLGNIALGSILAEDSAN -QLVDWMVANTTGAARLRAGLPSGWRIGDKTGTGDDGSAGDIAIIWPPGRGPIVAAVYMAE -TTVKMDEFNPVFAEIGKMITE-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01375 TaxID=2203194 RepID=UPI000F7A073B ---QFHDRLMELEKKFDARLGVYALDTEGGSTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVRYSREDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD -FLRDLLQRNATGAERIRAGLPSGWTVADKTGTGDYGTLNDIAVLWPPAKAPIVLAIMSSK -AAKDAPYDQALLAEAAKYVAETf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0004CB51EA ------EGFEKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLDTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAEDLRAFVLGKALRAPERA -QLTAWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. AY18-3 TaxID=2217814 RepID=UPI0011CBFD90 ---AMYKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7HQ27_BACCE ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITYTKDGLVEYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSERFETELNEAIPGDIRDTSTAKTLATNLKAFTVGNALPADKRK -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces baarnensis TaxID=66872 RepID=UPI0004AB42C4 ------EGFEKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLDTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAEDLRAFVLGKALRAPERA -QLTAWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Hyphomicrobium sp. (strain MC1) TaxID=717785 RepID=F8JDV0_HYPSM ------NAFAGLEKQYGGRLGVAVVDTGSGERM-AYRADERFPMCSTFKLLIVGAVLHNVD -KGSERLDRWIPFQASDLLDYAPVTKTAVGNGMTMSDLCAAAIEYGDNTAANLILKAVGGP -DGATRYVRSLGDEVTRIDRFEPDANTCIPGDPRDTTTPAAMLADLKALVLGDALSANART -QLLGWLNGCKTAARRIPADLPAGWISGDKTGSGANGTANDVAIIQRPNKKPLLVAAYSTG -VAAKPADRDPMLADVGRIVARHf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus proteolyticus TaxID=2026192 RepID=UPI0008FE43CE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IENLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00061DB914 -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKNDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KSFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A420H5U8_9BACI -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -STFEKILRKIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSKKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. XY006 TaxID=2021410 RepID=A0A231PI70_9ACTN ---SVTARLRRLEREHTARLGVYARNLRTGRTV-AYRSDERFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTRAYVTKYSPVTEQHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSVGDGVTRLDRWEPELNSAEPWRLTDTTTPRAIGLTYARLVLGDALAPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNHDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAKTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A1Z2KUZ2_9ACTN --qEAERAFGELERTYDARLGVYAVDTGSGRTV-THRPDERFAYASVCKAFLAGAVLKKNT ---LQRLDRHVRYGRDVPVGHSPITGRHVDSGMTLRELCDAAVRYSDNGAANLLFDELGGP -KGLQEALAAIGDRVTRADRYETDLSEAAPGDPRDTSTPRAMAADLRAFVLGDALAADERS -ALTDWLKRNTTGDKLIRAGVPAGWQVGDKTGSGGYGARNDIAVLWPPRAAPIVVAVFSSR -TAKDAKADDTLIAKATEATVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8DX17_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLH-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG3X2-1 TaxID=1053183 RepID=J7UNL3_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCF868 ---DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEEVFAEVSRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000E739AD7 ------KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTRANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGNYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. YLB-04 TaxID=2259171 RepID=A0A3D8GQS0_9BACI ---QLHRKFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQQYS ---IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLGEVAEAAVRYSDNTAGNLLLEKLGGP -EGFETALRQIGDRVTQADRYETDLNSAVPGDKRDTSTPKALATSLQALAVSDLLPTEKRT -ILTDWMRGNATGDTLIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATFDNTLIAEAAKVALN-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF38591 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP -KELTAFMHNMGDHVTRFDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Kroppenstedtia eburnea TaxID=714067 RepID=A0A1N7MLB9_9BACL ---AIKDDFAKLEEKFDARLGVFVLDTGTNQTV-TYRPDERFAYASTHKALAVGALLQQKS ---IEDLDQKITYTRDDLVDYSPITEKHVDTGMTLKELCDASLRYSDNTAGNLILEQLVGP -SGFKKSLRKMGDDVTNPERIEPELNEVKPGETQDTSTPKALATSLQAFTIGDVLPREKSK -MLTDWMKRSTTGDSLIRAGVPKSWEVADKSGAGLYGTRNDIAIIWPSKGDPIVLAVLSSR -EKKDAEYNDKLIAQATRVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00040E7229 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLETGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SM13 TaxID=1983803 RepID=UPI000CD53A41 ------EGFEKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B0HK74_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS ---IEDLDQIIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9DT24_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SDFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKRN -FLIELMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00115D8F82 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETALNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8FUH5_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLH-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000693B0B2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMD----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000FFE0296 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FMKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0013772D13 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FMKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0003981537 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FMKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A TEM n=1 Tax=Enterobacter kobei TaxID=208224 RepID=A0A658UC36_9ENTR --aDTLSAVKQAETTLAARVGYAELDLASGKVLgSYRVNERFPMMSTFKVLLCGAVLARVD -AGQEQLDRRLRWQKADLITYSPVTEKHLADGMTVAELCDAAITMSDNTAANVLLSTLGGP -QKLTAFLRKTGDAMTRLDRVEPELNEALPGDVRDTTTPVAMAKTLRQLLTGNTLSAASRQ -QLARWMEDDKVAGPLVRSVLPAGWYIADKTGAGERGSRGIVAALGPDGTPSRILVIYVTG -SSATMDERNKQIAAIGEAVIKQw ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LHE7_9BACT ---DFANRIRSIEQRTGARIGVTALDTSSGKGI-DYRSEERFPMCSTFKFLAAAVVLKRVD -DRQEKLDRFVSYGAKDILEYAPVTKAHLKDGMILGALCAAAIEQSDNTAGNLLLDTIGGP -VGLTNFVRSIGDEMTRLDRKEPELNSAIPGDERDTTTPAAMCADIQRLVLDNVLSESSRH -QLEDWLRHNETGALMIRAGVPKTWTVGDKTGRCGNGATNDVAIIRPPGRAPVVFAIYSIG -STSSADDRAAIVADAARVVV--- ->[subseq from] Beta-lactamase n=2 Tax=Alloactinosynnema iranicum TaxID=1271860 RepID=A0A1G6S0Z8_9PSEU -----RHRLRELEADYPGRIGVSAFNTGDGRAI-AYRAGERFAIASTFKVLAAAAILRKAR -RDPGLLDRVVHYTRADLVPHSPITEKHVATGMTVARLCEATITHSDNTAGNLLLRELGGP -GAITAFTRTLGDHRTRLDRWETELNSAIPGDRRDTTTPGSMTRNLYALTLGHGLVRPDRE -RLTGWLLANTTGGGRIRAGVPSDWKVGDKTGTPAYGGVHDVAIVWPPDARPLIISVYTTR -TDPDTPGEERVVRDITRVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF0948A -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas axonopodis pv. begoniae TaxID=473403 RepID=A0A2S6YG25_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFAVGDPRDTTTPAAMAVTLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2C5CUY1_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEF881C -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. higo TaxID=132266 RepID=A0A243KYI6_BACUH -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar ostriniae TaxID=180883 RepID=A0A2C9YZ75_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0007AB62F3 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDISIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BED00D5 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD133 TaxID=1053233 RepID=R8EIA2_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. mrc49 TaxID=2054913 RepID=A0A2M9NZH6_9BACI ------QNFAQLEEKFDAKLGIFALDTGTNQTV-TYHPDERFAYTSTHKALAVGALLQQKS ---LEDLKQRITYTQEDLVNYNPITEKHVDSGMTLKELSDASLRYSDNTAGNLILKQLGGP -AGFKKVLEEMGDDVTSPERIEPALNEVNPGETHDTSTPRALAASLQAFTLGDALPKEKRE -LLLDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKDAEYNDKLIAEATKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia speluncae TaxID=419477 RepID=UPI0012F4B651 ---ATTQAFADLEQTHGARLGVFAVDTGTGRSV-AHRPDERFPMASTFKGLACGALLHEHP -LSSGFFDRVIHYPPHELVEYSPVTEQHVGTGMTVAELCHAAITVSDNTAGNQILKLLGGP -AGFTAFLRSIGDDTSRLDRWETELNTAVPGDERDTTTPAALAAGYRTLVVGDALQVPERE -QLKSWLIATSSGEDRIRAGLPADWTVGHKTGTPAYGSALDVAIAWPPGRAPLVIAVLSTK -PEQDAEPDSALLAAATRAAVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011556E05 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIADATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A679HBC8_9BACI --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFCE390 -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPQNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2VEQ6_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Actinorugispora endophytica TaxID=1605990 RepID=A0A4R6V2V7_9ACTN -----EREFERLEGEFDARLGVYAVDTGSGDTV-AFNADERFAYASTHKAFSVGALLRQNS ---IEELERVVTYTEDDLVGHSPVTRRHVETGMTLREISDAAVRYSDNTAANLLFEELGGP -EGLDAALEEIGDDVTHVDRIEPDLSDWEPGDIRDTSTPRAMATTLRAYTLGDALPEEKSA -ILIDLMKRNLTGDALIRAGVPDGWEVGDKTGNANYGTRNDIAVLWPPNGDPIVLAVMSSR -DAEDAEHDDALIAEAAEVVVD-- ->[subseq from] Beta-lactamase n=3 Tax=Xanthomonas citri TaxID=346 RepID=D4T6V4_XANCI ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREEERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGVGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. FT14W TaxID=2654253 RepID=UPI0012654069 ---TAQTQLAALEQAAGGRLGVAAWRHGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLDQPVRYEKKELVTYSPITEKHLADGMTVAELCAATLQYSDNSAANFLMKILGGP -QAVTAYARSIGNTLFQLERWETELNSAIPGEVRDTASPTSMAHSLQQLLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG6X1-2 TaxID=1053195 RepID=J8B7I0_BACCE -----YKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKAVAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAINLKAFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWGVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEIIVN-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011F01728 --tEMKDDFAKLEEQFDAKLGIFALDTDTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9PFS5_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS ---IEDLDQIIKYTSKDLVNYNPITEKYVDAGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVRPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9PU86_9BACI -----NDSFTKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3868 TaxID=2029405 RepID=UPI000BAEF35C ----ATKAVEALEARNGGRLGVMILDVGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD -DGKAKLDDRIVYAASDVEPYSPVTKEHSGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP -QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRALLGDARRILLGDALSPASGK -RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILAAVYYTG -STAPRASREAVHADVARIIVETf ->[subseq from] CRH family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI0005B7B9B2 -----ADKLAKLERDFGGSIGVYAIDTGSGATV-ANRPNERFPLCSSFKGFLAAGVLAQSQ -DKPGLLDKRIRYSKAALPNWSPITTKHQASGMTVAELNAASVQYSDNGAANLLLKEINGP -AALTTFMRSIGDASFRLDRLEPELNSAIPRDPRDTSTPKAVAESAQKLALGKALPEPQRQ -QLADWLKGNTTGNARIRAAVPAGWEVGDKTGTCGYGTANDFAVIWPPKRAPIVLAVYTKH -AKKEAKHSDEVIAAAARAALEAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1S9U3L9_BACCE -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDIGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A37C554 ------DSFAKLEKEYDAKLGIYALDTVTNQTV-SYRSDDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTRKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTNSERFEPELNEVNPEETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIVWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKIVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9T583_BACMY -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASSHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3D7A5 -----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFE6DA6 -----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFE2A17 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7C2G9_BACCE --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0005CA249E -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE58_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQ------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8X4_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMVDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK696 TaxID=2512157 RepID=A0A4Q7T177_9RHIZ --dDVDQQLAALEKRTGGRLGVSVMDTGTNVSF-SNRETERFPLLSTFKVLASGMVLARVD -KGEENLERRVTYDQDKIVTYSPETEKHVGAEMTVGELCKAAITLSDNTAGNLLLESLGGP -EELTKWLRSIGDTSTRLDRIETALNEGRKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSRT -QLIDWMVANTTGAARLRAGLPEEWKIGDKTGTGNNGSAADIAVLWPESGSPILVATYIAE -ATAPVSELNEVFAEVAKIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cavernae TaxID=1674310 RepID=A0A433HUH2_9BACI ---HIHREFVDLESKFDARLGVYAIDTGTNRIV-SYRPNERFAYASTYKALAAGALLQHYS ---IDKLDELVTYKSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -EGFESALRQIGDNVTQVDRYETDLNSAIPGDKRDTSTPKALATSLQAFAVSDLLPTEKRT -ILTDWMRGNTTGDALIRTGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNTLIAEAAKVALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=N1LLK2_9BACI --qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDNGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Moraxellaceae bacterium TaxID=1889775 RepID=A0A4Q5VNW2_9GAMM -------FLAQLETQAQGRLGVSAINTATQQRI-DYRASERFPLCSTFKLIAVAAILHKSM -HSPNLLQQRMQYSMQQVKDYAPITSQHVDTGMTVSELCAACISYSDNTAANLLLQILGGP -AALTQFARSIGDPAFRLDRWEPALNTALPNDVRDTSTPAAMADTLQRLLVSNVLADTQRA -LLLYWLKNNTTGNARIRAGVPKDWVVGDKTGTGAYGTSNDIGIIWPAQQAPIIVAIYFTT -PLKTAKPNDPVIAAVSRIMSQVw ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0008FAE233 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-TYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALATSLQAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVLEGWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A3D9UT12_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. Root1204 TaxID=1736428 RepID=A0A0Q6S5T8_9RHIZ --nDIEQQLTALEKRTGGRLGVYVLDTKTKASF-AHRPDERFAMCSTFKALAAAFALARAD -KVEEKLDRRIPISKKHLLSYSPIVEKHVGGGMTVRELCDATVRYSDNAAGNLLLASFGGP -KGLTDWLRSIGDETTRLDRIEPELNEAKIGDPRDTTSPKAMTETLGKLLIGDVLSPASRD -QFSAWLVANTTGDRRLRAGLPKDWTIGEKTGTSGRGEAGDIGFMRPAEGHTILASVYIAE -GTKPTKELEPVFAEVGKLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SDLI1 TaxID=1774743 RepID=A0A109WEL2_9BACI ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-TYRPNEQFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHLTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTEDANYHNALISEAAKAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. NH11B TaxID=1866314 RepID=UPI0008FDA957 -----NQSFVKLEKDYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY53_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A1C4XUN8_9ACTN ------AELAALERRSGARIGVFAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DAERDRVVRYRRVDLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALREAGDRVTRPARAEPELNAATPGDERDTSTPRAMAGSLRAYALGEALPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMTSR -DSRDAEPDDALVAQAARATV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B2LJH7_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVIKFTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKNGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNGLPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AY18-3 TaxID=2217814 RepID=UPI0011CA4EC5 -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTRKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH -TKEDAKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aidingensis TaxID=384933 RepID=UPI00047CB7E3 ----MTDDFAELEDEFDAKLGVFALDTGTNETV-TYRPDERFAYASTFKVLAVGALLQQKS ---IADLNQRITYTRDDLVNYNPITKKHVETGMTLKELCDAALRYSDNTAGNLIFEQLEGP -GGLKKSLREIGDQVTNPERIEPELNEFKPGETQDTSTPKALADSLQAFTMGDVLPSEKRT -MLIDWMKRNTTGDTLIRAGVPESWEVADKSGAASYGTRNDIAIIWPPEEDPIILAILSRR -GKKDAEYNDELIAQAAEEVID-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. (strain 4-46) TaxID=426117 RepID=B0UJG8_METS4 -----VARLAALERHDGGRLGVTVRDTGTGRIL-SYRADERFPLCSTFKAVAAAAVLARVD -RGEESLDRRMAYGPEDLDAYAPETRRRVGEGIDLRAACAAAVIWSDNTAANLMLRALGGP -EAVTAFARAQGDAVTRLDRTEPSLNTAIPGDPRDTTSPAAMAALMERILVGPVLSAESRA -LLLGWMTQSPTGAERLRAGLSPGWQVADKTGTGANGTANVVALVRRPGGAPLVASVYLTQ -SPAPAEARNGLHAEVGRLVARTf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD048 TaxID=1053226 RepID=J8I825_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDTKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009ABFB74 -----YKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKAVAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIAINLKAFTVGNALPDHKRN -ILTEWMKGNATGDKLIRAGVPTDWGVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEIIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0010C2DABB ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDISIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CNZ296 TaxID=2572906 RepID=UPI0011A627F0 -------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI0006E4FAA7 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPSDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTASWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus siamensis TaxID=659243 RepID=A0A2K9KDG8_9BACI ----TNKKFVQLEKKFDARLGVYAIDTGSNKTI-TYRPNEQFAYASTYKVLAAAAVLKTSS ---NEKLNDIIRYTKDDLVTYSPITEKHLDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHLTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVWPPDRAPIVLAILSKR -FTEDANYHNALISEAAKAALD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011A6496D --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTSGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001298A642 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEINPGETHDTSTPKAIAKTLESFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8XHB2_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3CDC6 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6RSD3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SM1 TaxID=429004 RepID=UPI0009FD6AB6 ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLESFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPRGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF6F8A3 -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-SYRSDDRFAFASTSKSLAVGVLLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPVVLAILSNH -DKEDAEYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000CEEE536 ----LRAQWAEIERRTGGRLGISLLDSATGRRL-GQREDERFPMCSTFKFVLAAAVLQRVD -RGELTLAQRVKIRASDMLEHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGNP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGNALQPASRK -QLTDWMIHNRTGDTCLRAGLPRGSKIGDKTGSNGSDTRNDIAIIWPSAGAPLLLTAYLNG -ASVDSDARDAALKAVAAAVRD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00053401FE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] Beta-lactamase (Putative hydrolase) n=1 Tax=Bacillus sp. 71 TaxID=593090 RepID=A0A653V7Z3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRA -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C4FLM5_9BACI -----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWIVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001427BA2F ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKAITKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8CIW9_9BACI -hqATYKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLLVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011BDA006 --tEMKNDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Moraxellaceae bacterium HYN0046 TaxID=2283318 RepID=A0A345PBP9_9GAMM ----LTQELTALETSSKGRLGLALINTGTGQEF-QYRGDERFPFCSTFKLMLASAVLKKSM -TQASLLTQHIAYSEEDLLSYAPITRKNLAQGMSVSELCAATLQYSDNTAANLLIKQIGGL -EAVNHFAQSLGDRDFRLDRFEPDLNSALPFDIRDTTTPKAMANSLKKIALGNILAPNLRA -QLITWIKGNTTGDATIRAGAPSGWKVGDKTGSGNYGTTNDIGLLWPPSGEPVVLTIYFTQ -LKKDADNRRDVLAAATKLALSHy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFB852B -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAASALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=A0A5J6H705_9ACTN -------DFEELERTYGARLGVYAVDTGSGREV-THNDDERFAYASTFKAFAAAAVLREHS ---PSGMDEVITYSGDDLVAHSPVTEKHVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP -KGLASALEEAGDTVTRVERREPELNQWAPGSTRDTTTPRAWADALRAFVLGDALDGKERA -QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR -RTADAGYDDELIAEAASVVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. HDW3 TaxID=2714923 RepID=UPI001408A4FB ---------QAIEASSQGRLGVAVLNTHSGRLT-GHRLDERFPMCSTFKWLAAAHVLQRVD -QGLEQLERQIPFGPEALLHWSPVTERHADGNMTLAALCHAAITESDNAAANLILHTLGGP -KGLTQFARQLDDPVTRLDRWEPELNEATPGDARDTSSPRAMAGLLQRCVLGDALSARSRA -QLTQWLRGTRTNTARLAAQMPADWRVGSKTGTGGHGTTNDVGIYWPAGHAPLVVAAFLTE -SAASLQTREAALAQVAHAA---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. Root627 TaxID=1736572 RepID=A0A0Q8E6E6_9GAMM ---DATAQFTELERKHGGRLGVSILDAQSGRRI-RHRAGERFLMCSTFKWLAAAAVLARVD -SGRERLDRRVVYGKDVLLDYAPVTSKHVGAPLSVAELCAAAVTLSDNTAANLLLASMGGP -TAITAFARSLGDETTRLDRIEPELNLGSPGDIRDTTTPDAMLADLHRVLLGDRLSAGSRD -LLLQWLRGCSTGLDAIRAGLPANWTAGDKTGSGSQGETNDVAIIWPPRRKPLLVSAYYAG -SHAEPAERKAVLAAVGRIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5VEU4_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAAAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Betaproteobacteria TaxID=28216 RepID=UPI00036DDC55 -----AAQLARLEADTRGRLGVAAVNTADGRIL-SHRGDERFPLCSSFKAMLAAAILQHEP ----SLLDKRIRYTAADLVSHSPVTEQNLADGMTVGELSAATIQYSDNAAANLLMKQIKGP -AGVTAYARSIGDKAFRLDRWETELNTAIPGDPRDTTTPLAMMKSLQSVTLGPALTVDKRK -LMTEWLIGNTTGDTRIRAGVPYDWQVGDKTGTGSYGSTIDIGVVWPPGKAPVVMALYYTQ -PGKDDKANPEILASAARVVVEAf ->[subseq from] Beta-lactamase n=2 Tax=Nocardia farcinica TaxID=37329 RepID=A0A0H5NMB1_NOCFR ---AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLAEATRAVVT-- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=A0A379MC39_RHORH ---AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLAEATRAVVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0005ED1C9E ----SDRQFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVGTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 196mf TaxID=1761754 RepID=A0A2V4X4V1_9BACI --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTTGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] BES family class A beta-lactamase n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=UPI000FEB99C0 ---ELDSALARLEQQHHGRLGLAYIDSGSGESY-SYRGEERFAFCSTFKAVLAGAVLQQSV -SQPGLLDKQVHYAATDLLAYAPITKTHLDKGMRIGELAAAAVQYSDNTAANLLLQEIGGV -QALNRFVQGLGDPAFRLDRIEPHLNSAEPGDVRDTTTPLAMAHTLQAMTLGKGLPQAQQA -QLVSWLKGNTTGAQRIQAGVPAGWQVGDKTGTGGYGTTNDIAILWPEQGAPKVLAIYFTQ -PAANAQANRAILAEATRLVLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2T0EGZ3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHQDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0B4ZW49_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDE---------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF00F7B -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGKTHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000C7E44A1 ---DVTERLRQLEERTGGRLGVAVLDMETNISF-GYRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKX-LGSVLSENGRG -QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGAVSDIALAWPPGRGPLLVAVYTGE -AKAPVSDLNPVFAEIGKIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00142E7D11 -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPVTEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQVGDQVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B4CF4 ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQAASRK -QLTEWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00141B4F34 ---ELREAWAGIEHRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPEAMAATLRTLLLGNALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=S3I4V9_BACCE -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2B3FJ34_BACTU -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardia sp. 73-21 TaxID=1895809 RepID=A0A1Q4DLM6_9PSEU -------RLADLERRFDARVGVFAIDTGTGTTV-AHRADERFAMCSTHKALVAGAITLRGD ------LDRRITYTRAELVPYSPVTGTNVTAGMTLGQLCDAAVRHSDNTAANLLVRELGGP -AAVTAFARTLGDDVTRLDRTEPDLNEATPGDPRDTTTPRAIAADLRAMALGPALPEAGRA -ALTGWLVGATTGAGRIRAGVPGGWTVGDKTGSGGYGTANDIAVLWPPTGAPVVLAVLSSR -PTQDATSDPALLAQATTIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Methylophaga aminisulfidivorans MP TaxID=1026882 RepID=F5SX75_9GAMM ----WQDEVTQLETIYGGRIGVSAWNANDGQQL-HYRENERFAMCSTFKLLLVANVLQRID -QKQEKLERLISYDKSEILEYAPVTSQHLDKGMTVADLSKAALQLSDNTAANLLLNTLGGP -QGLTDYLRSLGDNTTRLDRIEPNLNTNLAEDPRDTTTPKAMLLTLKTLLLGDTLSEASKQ -RLIHWLIGNQTGDDKIRAGVPATWLVGDKTGSGANGANNDVAIIWPEAGHPYLLIVYYSG -SERSKNEKNAVIAKISQSVSKVf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1ZGP9_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHIDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGNALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pleomorphomonas oryzae TaxID=261934 RepID=UPI00040078B5 ---KADDEFAKLEKQSGGRLGVAAVDKASGKRI-AYRADERFAMCSTFKFLAAAAVLARVD -KGELKLDKSIAYGKDDLLSYAPVTKAHVAEGLTLEALCAAAVGVSDNTAANLLLKEIGGP -AGWTAYARTLGDTTSRLDRTEPELNSAVTGDARDTTTPAAMLANLDTVMIGDALKETSRD -KLEDWMVAGTVTGPLIKAGVPKTWQVADKSGSGANGTRNDIGVLYRPNTAPILAAIYTTG -SPLDMKGQNKVIADAAALIAARf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces variegatus TaxID=284040 RepID=A0A0M2GRS4_9ACTN -----TARLREIEREHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP -TAITRFARSAGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDALQPRDRA -RLTDWLLRNTTSGEKFRKALPADWLIADKTGGGRYGGNNDVGVTWPPDGPPIVMSVLTTQ -PEEDAPADNPLVARTAALLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=B0YKI3_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLRGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYTTG -SQATMDERNRQIA---------- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2B7HEQ7_BACTU ------DSFVKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTGKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5LVR2_9BACT ---EFENRVATIEARTGGRIGVAALDTASSKHL-DCRSEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVPYDAKDILEYAPVTKIHLKEGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -IGLTNFARAIGDKVTRLDRKEPELNSAIADDERDTTTPAAMLADMLQLLLGNTLSPSSRH -QLEQWLQANQTGASMIRAGVQTSWIIGDKTGRGANGATNDIAIMRPPGRAPILLVIYSAG -STATANDRAAVLAEAAKIVT--- ->[subseq from] Beta-lactamase n=8 Tax=Bacillus TaxID=1386 RepID=R8JUT8_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREMGDTVTNSERFEPELNEVNPGETHDTSTPKATAKTLESFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI00119C929D ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKTLREMGDTVTNSQRFEPELNEVNPGETHDTSTPKATAKTLESFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEIADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA3-9 TaxID=1053205 RepID=R8DA28_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IDKLNEVITFTKDDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000D02772A -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai B8W22 TaxID=1358420 RepID=A0A1G6TF53_9BACI ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGEPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4A TaxID=2714924 RepID=UPI001407E423 ---------ADIEAQSTGRLGVAVLDTASGHWD-GQRLDERFPMCSTFKWLAAAHVLQRVD -QGREQLERRIRFGRDALIEYSPVTESQAGKNMTLAELCHAAITVSDNTAANLILDTLGGP -QGLTAFARSLGDDVTRLDRWEPALNESKPGDPRDTTSPRAMATLLQQLVLGDALSSGSRE -QLTRWLQATTTNRGRLAADLPTGWKIGTKTGSSGNGSVNDVGVFWPPHRPPIIAAVYITA -GKGSSKSIEPAIATVARRIT--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A4U2ML01_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRNSDNTAGNILFNKIGGP -KEYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A2B9N7G6_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEQHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=BLAC_BACLI --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Arenimonas donghaensis DSM 18148 = HO3-R19 TaxID=1121014 RepID=A0A087MJ51_9GAMM ------DALRALEGRHGGRLGVFALDTGTGRTL-GQRGGERFAMCSTFKLPLAAQVLAAVD -AGRERLDRRLTWTPDDLVSWSPVVEKHDGAALAVDALCEATMTISDNTAANLLLAEHGGP -AGLTAWLRAIGDEVTRLDRNEPALNEATPGDPRDTTTPAAMVATLHKLLLGDVLSDASRS -RLTGWALANQTGDKRLRARLP-GWRVGDKTGTNNVGNSNDIGILWPPDRAPILVAAYYAE -SSGTPAERDTVLADVGHIV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AR2-1 TaxID=2217816 RepID=UPI0011ED97F7 -----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Desmospora sp. 8437 TaxID=997346 RepID=UPI000300B1DE ---AIKDDFAKLEEKFDARLGVFALDTGTNQTV-TYRPDERFAYASTHKALAVGALLQQKS ---IEDLDQKITYTRDDLVDYSPITEKHVDTGMTLKELCDASLRYSDNTAGNLILEQLVGP -SGFKKSLRKMGDDVTNPERIEPELNEVKPGETQDTSTPKALATSLQAFTIGDVLPREKSK -MLTDWMKRSTTGDSLIRAGVPKSWEVADKSGAGLYGTRNDIAIIWPSKGDPIVLAVLSSR -EKKDAEYNDKLIAQATRVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059) TaxID=509190 RepID=D5VMW0_CAUST --kDLSSRINELEKASGGRIGLAVLDTHDGRRF-AWRGDQRFRMCSTIKAPLSAAILRRVD -QGRERLDRRVTFGPEVLMDNSPIVEKHVQDGMTIGQLCEATITLSDNAAANLLFEALGGP -AALTRFLRAIGDQTTRSDRLEPELNRGPPDDPRDTTTPAAMLATWKTLLLDDALSPASRQ -QFRDWLIANKTGDRRLRAGLPPGWRVGDKTGNNGRDITNDVAIAWPPGRGPILIAAFHDR -GG-DEAARNAVHANVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4Q9Y9J1_BACMY -----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A1S9TQE9_BACCE -----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2A9VJR0_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETALNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A4R3SCC8_9BACI -----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1F3818 ---ELRDEWARIERRSGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLQRVD -QGALTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDACLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF85621 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A150CSG1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKYVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILKEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNREPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-340 TaxID=1463901 RepID=UPI00056941AF -----VDELRALEERYAARLGLYARNARTGQTL-SHRAGERFAMCSTFKAFAAAAVLRDHD --RCAPLDKVVHYPPADVLDNSPITKDHVDSGMTVGELCAAAIQYSDNTAGNLLLRELGGP -AGLTRFFRSLGDRVGRLDRWEPDLNTAVPGDPRDTTTPEAIATSLERVTLGRALTGGDRE -QLVTWLKGNTTSAERFRRGLPKGWVVGDKTGTGDYASANDIGVAWTTRGTPVVLAVLTSK -PAKDAAVDNALVAEAAGLVA--- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ad13 TaxID=989396 RepID=UPI0007B26393 ------DTVSQLETEVGGRIGVVLRHTGSDWTV-EHRADERFPMASTFKALLCGAVLSRVD -RGEESLGDLVTYKATELVSYSPVTENHLASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKDWRIADKSGAGHNGSRGIIGVIWPETGKPYLAAAYMMG -SDASFKQRNAVIAEIGKAMIE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis MC28 TaxID=1195464 RepID=K0FHY0_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Methylophaga sulfidovorans TaxID=45496 RepID=A0A1I3ZI98_9GAMM ---AWQDDVAQLETVYGGRIGVSAWNTNDGQQL-QYRENERFAMCSTFKLLLVANVLHRID -QKQEKLDRLISYDKSDILDYAPVTSQHLDKGMTVAALSKATLQLSDNTAANLLLNTLGGP -QGLTSYLRTLGDDTTRLDRIEPNLNSNLADDPRDTTTPEAMLFTLKTILLGDALSESSKQ -RLIHWLIGNQTGDDKIRAGVPSTWLVGDKTGSGANGANNDVAIIWPDAGQPYLLVVYYSG -SERSKSEKNMVIEKISQSVSKAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8W4_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGHEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIAVKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DCY113 TaxID=2603818 RepID=A0A5B0H6F1_9BURK ---AIREQLARIEAGSGGRLGVSIVDTTSSLHA-GLRSDERFPMCSTFKLLAAGAVLTRVD -RGEEDLQRRVVFSERDLVPNSPGTRRHTRELMSIAELCKAALTLSDNTAANLLLASFGGP -AAVTAFARSLGDGITRLDRIEPMLNDATPGDPRDTTTPNAMLGNLRELALGEHLSRSSRA -QLLAWLAANETGGARLRAKLPQDWGVGDKTGTGEHGTANDIAILWPPGRGPVLVTVYLTG -TDGDAARSNAAIASVAALVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFB6766 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEQHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus subtilis TaxID=1423 RepID=A0A6A8FKA9_BACIU -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKNANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF1E94C -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKDLADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A1E8PRG1_9BURK ---AAQTQLAALEQGAGGRLGVAAWRHGSAQRI-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLEQRVRYEKKELVSYSPITEKHLAEGMSVADLCAATLQYSDNSAANFLMRLLGGP -QAVTAFARSIGNTLFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLEHSLPAVQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKNADTNEDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B55BB0 -----NKEFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKNANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. LM6 TaxID=1938606 RepID=A0A1S6F388_9BURK ---AAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVAELCAATLQYSDNSAANFLMTILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPAAQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA2-9 TaxID=1053204 RepID=R8CTG7_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILRDMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rubrivivax gelatinosus TaxID=28068 RepID=UPI0002FAE015 -------AFGAIERSVAGRLGVWAYDLETGRSL-GHRQDERFPMCSSFKWLLAAAVLARVD -RGQERLERRIVFGREALLEYAPATSRRAGGAMTVAELCEAAVTLSDNTAANLLLDTLGGP -AGLTAWVRMLGDRTTRLDRREPDLNEARPGDERDTTTPQAMVLALRQVLFGGALSRRGGD -LLLQWMVASTTGAKRLRAGFPADWRIGDKTGTGGQGTTNDVAVVWAPGRAPLLLAAYLTE -SQAAIEAREAALARVAG------ ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00022BA80D -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFALDNSLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310) TaxID=365046 RepID=F5Y501_RAMTT ---KAQAGWRDLEATVGGRLGVAVLDTADGRLD-GHRLDERFPMCSTFKWLAGALVLHRVD -AGQERLDRRIRFGREVLLPHSPVTGEHAGSQMTLAALCEATIATSDNAAANLILRSFGGP -AALTGYVRGLGDTMTRLDRWEPELNEATPGDPRDTTTPRAMAGALRAALVGEALSPRSRE -QLGRWMEATVTNGQRLRAGLPAGWRMGSKTGSGARGTTNDVGIFWPPGRPPVIAAVYLTE -TQAPDGARNAVIAGVARQL---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. FDAARGOS_372 TaxID=2018066 RepID=A0A2A7UAA3_9NOCA ---AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLAEATRAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HF77_9BACT ---DAADQIAAIEARLGGRIGVAGLDTGNGKRI-DYRAEERFALCSTFKFLAAAAVLKRVD -EKKEKLDRFVSYDAKDILEYAPVMKAHLKDGMTLGGLCAAAIEQSDNTAGNLLLEAIGGP -AGLTNFARDLGDRVTRLDRKEPELNSAIPGDERDTTTPASILADVRQLLIGNPLSASSRQ -QLEAWLRANETGAAMIRAGISTNWIVGDKTGRGANGATNDIAIVHPPDRAPILLAIYCVG -TSASANDRAAAVAEAAKVMAESf ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora haikouensis TaxID=686309 RepID=UPI000B881C79 ------AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS ---EAELDRVVRYDRADLVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG -VLVDWLRRNTTGATLIRAGVPAGWRVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR -DAKDSQPDDALIAEAARVTID-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia farcinica TaxID=37329 RepID=A0A449HCB6_NOCFR ---AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLAEATRAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=A0A1G9UHZ2_9PSEU ------PDFTALEKQFGARLGVFAIDTATGKTV-SHRENDRFAMASTFKAYAVAALLKRHG ---TEVLSKRVHFTQQEIVTYSPVTEKHVGTGMTVGELCGAAITKSDNTAGNQMLKLLGGP -GELTKFAKSIGDGTTRLDRWETELNTAIPGDERDTSTPKALGSAYRDLVVGDVLPPAERE -QLKKWLLTNTTGGERLRAGIPKEWSIGEKTGTGDYASANDVGVAWTEKGTPIAIAVLTTK -DTKDAKADNALLARTAKLIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycetocola sp. 449 TaxID=2079792 RepID=UPI000D3D72A9 ---SADAEFDELEQKFDARLGVYALDTGTGLAL-EYRSDERFAYASTIKVVASAVLLDQTS ---DDELDTLVTYDESDLLDYAPITEQHVDTGMTLRELGDAAVRYSDNTAANLIFEQIGGP -AGLAAALTAMGDDVTQVDRIEPDLNEATPGDPRDTTTPEAFATTLEALVLGDALEASDRE -LLTEWLVGNTTGDKLIRAGVPTEWTVGDKTGSAGYGTRNDVAVIWPREGDPIVLTVLSSR -SEADADYDDALIAEATAVAIE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00115C29A4 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas axonopodis TaxID=53413 RepID=UPI0009965D3E ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREHERFPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVKIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGVGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVNDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9DP81_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAYNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. BRIP62411 TaxID=2182389 RepID=UPI000F8C3461 ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQQASRK -QLTDWMIDNRTGDTCLRAGLPRGWNIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar cameroun TaxID=180885 RepID=A0A242WNX4_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALLDHKRK -VLTEWMKGNATGDKLIRAGMPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFE2918 -----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRK -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Class A beta-lactamase n=2 Tax=Enterobacter bugandensis TaxID=881260 RepID=A0A167JWF6_9ENTR --eKLNHELTILEKNSGGRLGVALINTENNDLT-LYRADERFAMCSTSKVVAVSALLKKSE -SDKTILGKNIALHEAELVTWSPVTEKNITTGMTLGALSAATLQYSDNTAMNSILNYLGGP -SAVTAFARSIGDEKFRQDRTEPELNTAIPGDERDTSTPLAMATTLQKLTLGDALATPQRQ -QLVEWLKGNTTGAASIKAGLPEGWIVGDKTGSGDYGTTNDIAVIWPPEKSPLILVIFFTQ -PLQDAQSRKDILAEATKIVVSPf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429CDN0_9ACTN ---QFHDRLMELEKKFDARLGVYAVDTGGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVEYSRDDLMKHAPVTRRHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -AELTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTTDKRD -FLRDLFQRNTTGAQRIRAGLPSGWTVADKTGTGEYGTLNDIAVVWPPDKAPIVVAIMSSK -ATKDAPYDQALLAEAAKYVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. AA23 TaxID=1854058 RepID=UPI000801ACF2 ----ATKAVEALEARNGGRLGVMVLDIGTNAAI-EYRADELFPMTSTFKFLAAAGVLKAVD -DAKAKLDDRIVYAASDVEQYSPITKDHAGDGMKLEDVCAAAVVWSDNTAGNLLLRLLGGP -QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK -RLEAWLFEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPDGAPILVAVYYTG -STAPRASREAVHADMARIIVETf ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora haikouensis TaxID=686309 RepID=A0A1C4XQ70_9ACTN ------AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS ---EAELDRVVRYDRADLVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG -VLVDWLRRNTTGATLIRAGVPAGWRVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR -DAKDSQPDDALIAEAARVTID-- ->[subseq from] Beta-lactamase n=1 Tax=Cosenzaea myxofaciens ATCC 19692 TaxID=1354337 RepID=A0A198FJY0_9GAMM ---------KITESQLNGRVGYTVLDLTSGNILeNYRAKERFPMMSTFKVLLCAAVLSRVD -NGQEQLDRRIKYNQNDLIEYSPITEQHITDGMTVGELCEATITMSDNTAANLLLTTIGGP -QKLTEFLRKTGDQTSRLDRNEPTLNEALPGDERDTTTPEAMAKTLHELLTGKTLTASSQQ -QLMDWMIADKVAQPLLRSVLPTGWFIADKTGAGKHGSRGIIAVMGPDKNSARIIVIYLTE -NKATITELNKYIAEIGSSLIKNw ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Alg231-02 TaxID=1922223 RepID=UPI000D5508A1 ------DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSSVD -RGKENLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEAKRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGAGHNGSRGIIGVIWPETGKPYLAAAYMTG -SDASFKQRNAVIAEIGKAMIE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. GV031 TaxID=2135727 RepID=A0A4R2X085_9RHIZ ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGQENLERRVVYNKVQLVAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDVAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWLVANTTGNERLRTGLPDSWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTG -ATAPAAEVNPVFGEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A109N1U7_9BACI ------QNFAQLEEKFDAKLGIFALDTGTNQTV-TYHPDERFAYTSTHKALAVGALLQQKS ---LEDLKQRITYTQEDLVNYNPITEKHVDAGMTLKELSDASLRYSDNTAGNLILKQLGGP -AGFKKALEEMGDDVTSPERIEPALNEVNPGETHDTSTPRALAESLQAFTLGDALPKEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKDAEYNDKLIAEATKEVIQ-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002796FBE --qATHKEFSQLEKKFDTRVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALLAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEASYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1BKA4_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEAIYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FFI8_ECOLX ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATWDE---------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TaxID=1931 RepID=A0A3D0QV17_STRSQ ------REFKDLEREYDARLGIYAIDTGTGHEV-AYNDGERFAYASTFKALAAGAVLQKYS ---LSGLNRVIKYSEDDLVEYSPVTEKHVGTGMSLGELCEAATRHSDNTAANLLFDALGGP -KGLGAALEEMGDDVTRMERYETQLNEWTPGATRDTSTPRALAEDLRAFVLGDALGKGERA -QLTKWMRTNTTGAELIRAGTPEDWVVGDKSGAGSYGTRNDIAVVWPPDSAPIVVAILSNR -SKADADYDNELIAEAASVVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. RIT694 TaxID=2666190 RepID=UPI0012ACD416 -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKEWDVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium 66-5 TaxID=1895728 RepID=A0A1M3BYG9_9BURK --------WQAIETASQGRLGVAVLDVASGAFS-GNRLDERFPMCSTFKWLAAAQVLQRVD -QGHEQLKRRVRFGKEVLLPWSPVTERHVDDGMTVGDLCQAAVAMSDNAAGNLLLQSLGGP -QGLTQFVREQGDAVTRLDRWEPQLNESTPGDPRDTSSPRAMAGLLQRLVVGQALSPGSRE -QLARWLRQSKTNAQRLGAGLPAQWRVGSKTGTGPHGSTNDVGVYWREGRPPIVVVAFLTE -SAASLAVRETAIAQVAKAVF--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca TaxID=47850 RepID=A0A1C6SE09_9ACTN -------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARVTV--- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CF3FEB5 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPFMSTGKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLTTTIGGP -KELTAFMHNMGDHVTRYDRYYGELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A2D9LIJ2_HALSX ---RITAELERIEQTLEARIGFAAHNLATSQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALETEVSFEESDLVTYSPVTEQYAGHRMTLFELCDATMTTSDNTAANLVLQALGGP -EAVTAFARSMDDPVTRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ -QLEAWMKGNAVADSLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVVVFYITE -TDASFKERNAAIASLGEVVQ--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 5mfcol3.1 TaxID=1761756 RepID=A0A1I3Z0C1_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHKDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0011AAAB3E --tEMKNDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRK -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas lionensis TaxID=1144478 RepID=UPI0009F27D9F ---RITAELERIEQTLDARIGFAAHNLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALETEVSFEESDLVTYSPVTEQYAGHRMTLFELCDATMTTSDNTAANLVLQALGGP -EAVTAFARSMDDPVTRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ -QLEAWMKGNAVADGLFRAAMPFDWVMADRTGAGGYGSRSITAIIWPPEQPPTVVVFYITE -TEASFKERNAAIASLGEVVQ--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001374ACA0 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWIKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8U9T1_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITKKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X9W9_9BACT ------RQFAELEARTGSQIGVAAIDISTKRGV-DYRANERFLMCSTFKAMAVAAVLQRVD -QKKEKLDRFVTYGEAQLLEYAPVTRAHVKEGMTLEALCEAAIRQSDNTAANLLLNVLGGP -KGFTEFARSLGDEFTRLDRMEPELNMGSAGDERDTTTPAAMAKDLQRLFTSDVLTVESRK -RLEDWMAANETGTRMIRASVPAGWRVGDKTGRSGKGATNDIAILRPPTGEPIFMAIYTNA -PNESSEGREKLVAEVARIALE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001124D12C --qATHKEFSQLEKKFDARLGVYAIDTSTHQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPDRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E5A2886 ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHAPITERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVHAAARDAALKAVAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. THAF82 TaxID=2587861 RepID=A0A5P9D4C0_9RHOB ----IERAVKDAQARLSARIGVVVVDRQTGENW-THRAQERFPLNSTFKTFLCAALLHQGE -AGETDPTRRVEIRGADLVSYSPVTETKVGTDMTLLELCEATVTKSDNTAANLVLDDIGGP -DALNRYLRGIGDTVTRLDRREPEMNYGQPGDERDTTTPAAAAATLQKLVLGNALSADAKK -LLQSWLEDNRVGNSTLRAGLPAGWKVADKTGAGGNGSRSNIAVIWPEGRAPVVVAVYITE -TQASFKARNQAIADIGRAIAS-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1G7UCQ5_9BURK -----AAQLAQLEQSSGGRLGVFALNTATGAQI-GHRADERFPFCSTFKVILIGAILARST -QVAGLMQQRIHYAQSDVVHYSAVTAEHVSEGMTVAELCAAAIQRSDNTAANLLIKLLGGT -NAVTAYARLIGNPVFRLDRLETSLNDAIPGDPRDTATPAAMVRSLQTLTLGAALPLAQRT -QLLDWLRGNQMGAQRIGAALPAGWTRGDKTGTGDYGTANDLGLVWPPSRPPLILGIYHTQ -PQQDAKARDDVIAAAARIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Falsochrobactrum ovis TaxID=1293442 RepID=A0A364JT59_9RHIZ ---ELISKVQEAEKQINARIGLAIRNTGTGETW-RYRADERFPMASTFKLLACAALLAHID -EGKEDGNRRVTINQNDIVTYSPLTENWVGQAVSLETLCDATMRTSDNTAANKVLEAIGGP -QGLTAFLRAQGDIVTRLDRWETELNEAIPGDPRDTTTPDAIVNLSHKLLLEDGLSAHSRK -TLTNWMMSNEVGGPLMRAGLPETWRIGDRTGAGGYGTRGIVAIIWPPEQKPLIAAIYITQ -TDASIEQRNAAIASIARQLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavovariabilis TaxID=284031 RepID=UPI0005EBFD2A -----TARLREIEREHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP -TAITRFARSAGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDALQPRDRA -RLTDWLLRNTTSGEKFRKALPADWLIADKTGGGRYGGNNDVGVTWPPDGPPIVMSVLTTQ -PEEDAPADNPLVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF314EA -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTVLPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] LEN family class A beta-lactamase n=1 Tax=Klebsiella variicola TaxID=244366 RepID=UPI000D7486DD ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPVVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTHLDRWETALNEALPSDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Azorhizobium sp. AG788 TaxID=2183897 RepID=UPI001061D295 ---DLAQKIAALEARSGGRLGVAAIDTGSGARF-AHRGGERFPMCSTFKFLLAAAVLAEAD -RGHLKLTDMVPITRADLIAYAPEVEKHVGSGMSLSDLCAAAVIWSDNGAANLLLRQIGGP -AAVTRFLRSAGDPVTRLDRAEPELNVVPEGSDMDTTTPDAVADDMVRLVLGDVLAPASRG -ALKDWLIGCRTGDKRLRAGLPKGWTVGDKTGTGPTGTSNDVAIAWPPGRAPLVIASYLTA -SRLDGRGSDAIHADVARAVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDAFBF6 ---DADVRLAALEKATGGRLGVSVIDVAMNISF-GRRQEERFAMCSTFKMLAAACILARVD -NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP -EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKLLLDDAMSEKSRD -QLTAWLVGNKTGDKRLRAGLPKGWTVGDKTGTSATGAIGDVAIVWPSPNRPILITAYIAE -ATKPAKELEYIFAEIGKMV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis subsp. medellin TaxID=79672 RepID=A0A243NIX5_BACTV -----HDSFAKLEKEYNAKLGIYALDIGTNQTV-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPEETRDTSTPEAIAKTLQSFTLGSALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00137663F5 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIRYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTNKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus intestinalis TaxID=1963032 RepID=UPI000B437862 -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNKVIQYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8EYN3_BACMY -----NQSFTKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella aerogenes TaxID=548 RepID=UPI0007B38BDC --eKLNHELTILEKNSGGRLGVALINTENNDLT-LYRADERFAMCSTSKVVAVSALLKKSE -SDKTILGKNIALHEAELVTWSPVTEKNITTGMTLGALSAATLQYSDNTAMNSILNYLGGP -SAVTAFARSIGDEKFRQDRTEPELNTAIPGDERDTSTPLAMATTLQKLTLGDALATPQRQ -QLVEWLKGNTTGAASIKAGLPEGWIVGDKTGSGDYGTTNDIAVIWPPEKSPLILVIFFTQ -PLQDAQSRKDILAEATKIVVSPf ->[subseq from] class A beta-lactamase n=1 Tax=Afifella aestuarii TaxID=1909496 RepID=UPI000FE33685 ----LTRTLSEVEQRLNARLGAYVLDIETGREW-AQRADERFPMCSTFKLLACGAVLAKVD -MGEEDLERRISFEEKNLVTYSPVTKEHVGGEMTLADLCVAAMTQSDNTAGNLILDSLGGP -PAITSFARSIGDQVTRLDRRETELNEATPGDPRDTTSPRAMARDAQTLLVKGSLSDRSRL -YLKRWMCTNKTGDEKLRAGLPGDFLVGDKTGGGGNGTMNDVAVIWPSGRKPIIASIYLTE -SGASFDERNAGFAEIGKAIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A4U2X889_BACMY -----NQSFAKLEKEYDAKLGIYALDTSTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 12 TaxID=463035 RepID=A0A261V9F8_9BORD ---DAQRQLARLEAREGGRLGVHLLDLQSGYTA-GYRADERFALCSTFKVLAVAAVLARVA -RGEDDLSRPMRLSAADLVAYSPVTQQRLNEGMTLGHLCEAALLVGDNTAANLLLSTIGGP -PGVTAYARTLGDTVTRLDRLETALNQAQPGDERDTTTPAAMAGNLRQLVLGEALPEPQRE -RLRDWLLHCRTGQERLRAGLPAGWAFGHRTGAGEHGTCNDIGVAWPPSTGPVVISAYLTE -SPLPPPERERVLADAARILVH-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A366JPI6_BACFI ---NTNQKFKQLEKEFDARLGVYAYDTGTKKTI-AYRSNERFAYASTFKPLAAAILLERKS ---LEEMDEIVTYTSEDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP -DGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPKALAASLQKVLIGDFLPEEKRN -LLTDWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIVTILSSR -DSKDAEYDNALIAKTAEMTIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. EE-W1 TaxID=2662453 RepID=UPI0012FC8D3F -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSEQFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. KBS0711 TaxID=1649647 RepID=A0A0M2WM99_9BURK ---AAQTQLATLEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=A0A2D3T1Y1_9ENTR -hqATIDKVKESERQLNARVGYVELDLANGQILnTYRPEERFPMMSTFKVLLCGAVLSRVD -AGLEQLDRRIKYRQSDLVKYSPMTKQHLADGMTVAELCSAAITVSDNTAANLLLSTIGGP -KGLTSFLQKTGDQVTRLDRWETELNQALPGDERDTTTPKIMAQTLHNLLTGKILFVKSRQ -QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE -TQATMDERNKQIAEIGASLIKNw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF5EE7F -----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVKPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F954_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIEGP -KELTTFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A657UWL1_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSEQFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Cohnella sp. CC-MHH1044 TaxID=2565925 RepID=A0A4V3WES1_9BACL ----IDRDFVQLESKFSAHLGVYAIDTGTKRIV-AYRPDERFAYASTFKALAVGAVLQQNS ---IDELDKMITYTDKDLVNYSPITEKHVHAGMTLRELSEAAICYSDNTAGNLLLKELGGP -NGFRSALMNIGDSVTNPERFETDLNEAIPGDIRDTSTPRALATSLQAFTLGGVLPTDKRT -ILTDWLKGNITGDNLIRAGVPEGWKVGDKTGAGGYGTRNDIAVVWPPNRDPIVIAILSSR -NTQNAAYDDALIAQATKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. WMMB235 TaxID=1172030 RepID=UPI0008DA22D5 -------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD86353 ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGQENLERRVVYDKVQLVAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLLLESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDVAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWLVANTTGNERLRTGLPDSWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTG -ATAPAAEVNPVFGEVGRIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CNY236 TaxID=1169152 RepID=UPI0004268199 ---AASAQLADLERRYDARVGLFAVDTGTGRIL-THRADERFPLLSTFKPLAAAALLQAHP -LDTGYFDEVVRYAESDLLPYSPVTETKVAEGMTVAQLAEAAITRSDNTAGNLLLRELGGP -EGLTAFLRTIGDSTSRLDRWEIELNTAIPGDERDTTTPAALAADYRAVALGDALGAPERD -RLNSWLQANTTGDTRIRAGLPTGWIVGDKTGTGSYGTANDVAIIRPEGGAPIVIAILTRR -SDADAAANNDLLVDVTRVVVDE- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=A0A031GEI8_9BURK ---TAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSA -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMNVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPVPQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLIIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora chalcea TaxID=1874 RepID=UPI000CE36DC7 ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALREVGDSVTRPVRTEPDLNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD -LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR -DRRDAKPDDTLVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 22-7 TaxID=2709707 RepID=UPI0013D2F50D ---NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLERKS ---LEEMDEVITYTRDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLMLEELGGP -EGFEAALKEIGDTVTKPERFETDLNEAEPGDIRDTSTPEALAISLQKVLIGDFLPEEKRN -ILTDWMRGNATGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR -DSKDAEYDNALIAEAAEMTIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0012930798 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IKKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. GV014 TaxID=2135502 RepID=A0A2U0YYF4_9BURK ---SAEAQLAELERSCGGRLGVVGFHTRSGVRV-QHRAHERFPLCSTFKLMLSASVLERSA -QDASLLQRPMCYGKADLIANSPVTEKHVATGMSVAELCAATIQYSDNAAANVLLKLVGGP -AEVTAFARRIGDQAFRLDRTEPELNTSIPGDLRDTTTPAAMSDSVQRLVLGDALGAGQRE -QLKTWLLGNTTSADRFVAGVPAGWKVADKTGAGSYGSNNDVGVLWPPAGEPLVLSVYLTF -AQKDAKTRNDVVAAATRIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar toumanoffi TaxID=180862 RepID=A0A243EDF6_BACTU ------DSFVKLEKEYNAKLGIYALDTGTNQTV-TYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTGKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B8ZE77_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGARNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces variegatus TaxID=284040 RepID=UPI0004CD94BF -----TARLREIEREHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP -TAITRFARSAGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDALQPRDRA -RLTDWLLRNTTSGEKFRKALPADWLIADKTGGGRYGGNNDVGVTWPPDGPPIVMSVLTTQ -PEEDAPADNPLVARTAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2A7GU92_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKCK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000BF25618 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDNRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTVLPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A443T8M1_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILKEIGDTVTTSERFEPELNEVYPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000988FBDA -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQVGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFILDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF44784 -----KHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYAQSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2H3PF36_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRLETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHZ0_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. sk2.1 TaxID=2478959 RepID=UPI0011E67903 ----FTQQFKQLEREFDARLGVYAIDTGTGREV-THNADERFAHASTFKALAAAAVLRKYS ---LDGLDEVVTYSRDDLVSDSPVTEKHVDTGMTLKALCDATVRYSDNTAGNLLLDRLGGP -RGLQAVLAGLGDDVTRMERYEPQLNEWSPGATADTSTPRALAKDLRAFVLGDVLGENERA -QLAQWLRTNTTGDELIRAGVPGNWVVGDKTGAGGYGTRNDIAVVWRPGAAPIVMAILSNR -GEADAEYDNELVARAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1I2V431_BACME ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGEPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFE15D5 -----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGARNDVAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas euvesicatoria TaxID=456327 RepID=UPI0004DFBCB3 ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQQVRIRASDMLEHALVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A1C5A935_9ACTN ---AADHEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DKKDATPDDAVIAQAARVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008696A96 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKTLREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=2 Tax=Comamonadaceae TaxID=80864 RepID=A0A0S9M535_9BURK ---QAESALAALEQGFAGRIGVCALDTADGALL-GQRADERFPMCSSFKALLAAAILARSS -TEPGLLAQSVRYTRGDLLPHSPVTTQHLAQGMRVDALCEATVQTSDNAAANLLLQRIGGP -AGLTAFMRSIGDAQFRLDRWELELNSSLPGDPRDTTTPRAMAESLRKLVVGDALAPAQRE -QLATWLRGTVTGAARIRAGMPAGWVVGNKTGTSGYGSAIDMAVVWPPARAPLVLAVFTTR -HAADAPALDAPIAQAARIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00087238CB -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000E212F8C ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATA------------------ ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. TSRI0078 TaxID=1718951 RepID=A0A1Q4WQ84_9ACTN ---ELAREFERLEEEFDARLGVYAVDTGTEEEV-AHRPDERFAYCSTHKALSAGAVLQRNT ---PEEMEEVITYTEDDLVNYAPITEQHVDTGMTLMEVTDAAVRYSDNTAANLLFEELGGP -DGFEEAMEAVGDDVIEVDRVEPGLSEAAPGDIRDTSTPRAMAESLRKFTLGDALPEDRRD -VLTDMLINNVTGDELIRAGVPEGWEVGDKTGSGGYGTRNDIAVLWPPEGDPIVLAVMSSR -DEEDAEYDNALIAEAAGVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas cassavae TaxID=56450 RepID=UPI0004926437 ----LRAHWAEIERGTGGRLGISLLDSASGWRI-GQRENERFPMCSTFKLVLAAAVLQRVD -EGQLSLAQPVKIRASDMLEHAPITERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGDP -AGVTAFLRSIGDAKTRSDRYEPEMNQFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRR -QLTDWMIDNRTGDNCLRAGLTADWKIGDKTGSNGTDTRNDIAILWRPDRAPLLLTTYLNG -AKVDGSARDAALKDVASAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF7D1ED ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDHVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPENKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] UPI00100527B4 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00100527B4 -----NKKFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRM -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEFC0AB -----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. Pch-S TaxID=2082387 RepID=A0A4P6H5I6_9RHIZ ---EAENKLAELERKHPGRFCVTILDLGSGKRI-QHRADERILMCSTFKALLAALVLARVD -KGEARLDERITFTSKDLVAHSPVTKPHADGSMTIAELCDATVTISDNTAANLLLARFGGP -AALTAFCRRIGDDVTRLDRTEPELNHDGPDDQRDTTTAAAMTETLRKLLFTDVLSAASRH -QLAAWLITNKTGDRRVRAGLPGDWLVGDKTGTNGHGNANDIAVIWPPDRAPLIVTVYCEI -PKISSSERDAAIAEIGRIAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A4U2N188_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDSVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FL85_9PSEU ---QFHDRLMELEKKFDARLGVYAVDTGGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVDYSRDDLVKHAPVTGRHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -AELTAFTRSLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYRKIVLGDTLPADKRD -FLRDLFQRNTTGAQRIRAGLPSGWTVADKTGTGEYGTLNDIAVVWPPDKPPLVVAIMSSK -AAKDAPYDQALLAEAAKYVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C5A827_9BACI -----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIENRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Haematospirillum TaxID=2622088 RepID=UPI00143A6F8D ----AVQRLSDLEGTFDGRLGVFAFDTGSGASL-AWRSEERFPVCSTFKAFLAAAILHRST -SDHGLLDRVISYPLEELVSYSPVTQQHVHSGMRVRDMCAAAIQYSDNTAANLLMRILGGP -DAVTTFMRQAGDTDFRLDRWETDLNTAIPGDLRDTSTPVAIARSLDRLLFGDVLSDMHRA -VLQDWLKGNTTGASRIRAGVPEGWMVGDRTGSGSYGTANAIGVLWPPGRKPVIASIYTTQ -HYREAVWRDDIVAQATRIIVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VDM053 TaxID=1053249 RepID=R8P6X1_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAIGALLQKTS ---IEDLDQIIKYTSKDFVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodoligotrophos sp. lm1 TaxID=2561934 RepID=UPI0010C97029 ----LSQKLDDIEKRLGGRLGAVVIDTATGRQW-SRRANERFPLNSTFKAFACAATLARVD -AGEEDLTKSITFDAKDLVTYSPVTEKRVGGKMTLFELCDATMSMSDNSAANMVLGSLGGP -QGLTSFMRSIGDDVTRLDRWETELNEATPGDLRDTTTPKAIAASFQNLLVGDVLSPRSRQ -QLEDWLIGNEVSGPMLRAGLPAGWRIGDRTGAGGHGSRSIVAVIWPPRRKPVIAAIYMTE -VQASMQDRNAAFAELGRALVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A386WJX7_9ACTN -------ELAALERRSGARIGVFAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DAERDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALREVGDRVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGEALRPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMTSR -DSRDAKPDDALVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF85F55 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus albus TaxID=2026189 RepID=UPI0014192192 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYTSTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGLTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVYPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009AC4B27 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAVYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces platensis TaxID=58346 RepID=A0A1Y2NG80_STRPT ----SAQAFKDLERKFDARLGVYAINTGTGREI-TYHQDERFAHASTFKALAAGAVLQKYS ---LPGMDKVITYSRDDLVPHSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP -KGLDAVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA -QLAKWLRTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR -TQKDAKYDDALIAQAASVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces libani subsp. rufus TaxID=249582 RepID=A0A640UBS2_9ACTN ----SAQAFKDLERKFDARLGVYAINTGTGREF-TYHQDERFAHASTFKALAAGAVLQKYS ---LPGMDKVITYSRDDLVPHSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP -KGLDAVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA -QLAKWLRTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR -TQKDAKYDDALIAQAAAVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=UPI000EF4F472 -----NEKFVQLEKKFDAKLGVYAIDTGTNKTI-SYRPNERFAYASTYKVLAAAAVLKKNA ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSAAKALATDLKAFTVDNNLTPDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR -FTEDANYDNALIAEAAKVVLNNf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5P0_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGS -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -LLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2A7HJQ2_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETALNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI09_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWXKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQ--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Fictibacillus sp. FJAT-27399 TaxID=1729689 RepID=UPI0009E701F1 ---HIHREFADLESKFDARLGVYAIDTGTDRIV-SYRPNERFAYASTYKALAAGALLQHYS ---IDKLDELVKYTSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -TGFETALRQIGDNVTQVDRYETDLNSAIPGDKRDTSTPKALVTSLQAFAVSDLLPTEKRT -ILTDWMRGNTTGDALIRAGAPTDWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DAQNATYDNNLIAEAAEVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. BL1 TaxID=2478709 RepID=UPI000EF5E229 ------AELAALERRSGARIGVFAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DAERDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALREVGDRVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGEALRPADRD -VLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMTSR -DSRDAKPDDALVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces africanus TaxID=231024 RepID=UPI00142DF261 -----TARLRELEREHTARLGVYARNLRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITEDNVATGMTVGELCDATIRFSDNAAGNLLLKELGGP -TAITRFARSVGDAVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA -RLTDWLLRNTTSDERFRKGLPADWLVADKTGGGRYGGSNDVGLTWPPDGAPIVLSVLTTQ -PEEDAPADDALVAKTAAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B6CWH9_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -GKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A0J7DCB6_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -GKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEB4E96 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILNQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sioyaensis TaxID=67364 RepID=A0A4V1NNT6_9ACTN -----HAALRRLERAHRARVGAFAHNTRTGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRVHYTAADVVPNSPVTGKHTATGMTIAELCAAALQRSDNTAANLLLRALGGP -TAVTDFARSLGDRTTRLDRWEPELNSAEPGRTTDTTTPAAIARTYARLLLGDALTPADRG -RLTAWMKANETNTERFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGT -AQQAAPSDDPLVAGVTRVLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas citri pv. fuscans TaxID=366649 RepID=A0A2H1SF88_XANCI ---MLRARWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQQVD -QGKLTLARQVKIHASDMLEHAPVTERHVGGSLSIGELCRATMIYSDNPAANLLFPLVGDP -AGVTASLRGIGDAQTRTDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGGPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428Y0S5_9PSEU ---QFHDRLMELEKKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSREDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRSLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDALTADKRD -FLRDLLQRNATGADRIRAGLPPGWTVADKTGTGDYGTLNDIAVVWPPAKAPIVLAIMSSK -AAKDAPYDQALLAEAAKYVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF75BDF ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGSP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenovibrio sp. JE_KL2 TaxID=2651188 RepID=UPI00128BDDEF ---NFKQQISELESTFGGRLGVAVWDASSGFQL-QYRGNERFALCSTFKFLLAASVLAKVD -AKEESLSRVVTYSTSDLLNYAPITRKNLHNGMTVSQLLAAALQHSDNTAANLLFEPVRGP -QGLTTFMRSIGDRETRVDRIEPHLNTNIPGDERDTTTPNAMLKSMKKILLGHVLSEASKN -QLTQWMLNNTTGANKLRAGIPTYWPIGDKTGSGNNGAMNDIAIMWPDADDPILVAVYYTG -SKEPFETRNHVLEQVGRIISDQf ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium amorphae TaxID=71433 RepID=UPI0011866D6C ---EAENKLAELERKHPGRFCVTILDLGSGKRI-QHRADERILMCSTFKALLAALVLARVD -KGEARLDERITFTSKDLVAHSPVTKPHADGPMTIAELCDATVTISDNTAANLLLARFGGP -AALTAFCRRIGDDVTRLDRTEPELNHDGPDDQRDTTTAAAMTETLRKLLFTDVLSAASRH -QLAAWLITNKTGDRRVRAGLPGDWLVGDKTGTNGHGNANDIAVIWPPDRAPLIVTVYCEI -PKISSSERDAVIAEIGRIAAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A101QJT1_STRCK -----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFYRSLGDEVSRLDRWEPELNTAVPGDPRDTTTPEAIAASLERVTLGRALARADRE -RFVGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTTRRTPVVLAVLSGK -STPDAPVDEALIADAAAVVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=UPI0009F17B27 ------PDFTALEKQFGARLGVFAIDTATGKTV-SHRENDRFAMASTFKAYAVAALLKRHG ---TEVLSKRVHFTQQEIVTYSPVTEKHVGTGMTVGELCGAAITKSDNTAGNQMLKLLGGP -GELTKFAKSIGDGTTRLDRWETELNTAIPGDERDTSTPKALGSAYRDLVVGDVLPPAERE -QLKKWLLTNTTGGERLRAGIPKEWSIGEKTGTGDYASANDVGVAWTEKGTPIAIAVLTTK -DTKDAKADNALLARTAKLIVE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFA0096 -hqATYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGITLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00033136DA --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKYVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILKEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNREPIIIVILSSK -DEKEATYDNQLIADATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces auratus AGR0001 TaxID=1160718 RepID=J1RNF2_9ACTN ----AHAALRRLERAHRARVGAFAHNTATGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRVHYTAADLVANSPVTGKHVATGMTIAELCAAALQRSDNTAANLLLRALGGP -TAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTTPAAIGHTYARLLLGDALTPPDRN -RLTAWMKANETNTDRFRAALPRDWALADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTGT -AQQAAPADDPLVAGVTRVLAK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BEF1F2D -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -SKLQAVLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAKPERA -RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Bordetella genomosp. 8 TaxID=1416806 RepID=A0A1W6YK10_9BORD ---ACNTEFADLERAHDRRLGLHAVDTASGKEI-AYRAGERFPFCSSFKAVLAAAVLARDA -RQPGVLDRRISYTRHDLAPYSPVTQNHAGDDMRVADLCAATLRYSDNTAANLLLHLIGGP -PALTAFARAAGNASFRLDRYETALNTAIPGDPRDTSTPRDMGVLLRALMLGDALPARAQA -TLADWMLGNRTGDRRIRAATPADWKVADKTGTGDYASASDIGVLWPPGRRPIVLAIYTTA -RDSKAKADEDLIAAASRIALR-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00081B6929 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERISYGTADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIAADYRALVHGDALPAAGRA -LLTDWLVRNTTGDDRIRAGVPRGWKVGDKTGTAEWGRAHDVAVLWPGDGSPLVLSVLTDR -PDRAASGQDELVAEATRRALD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD107 TaxID=1053229 RepID=J8JVH4_BACCE -----NQSFVKLEKKYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKKNTTGDNLIRAGVPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas monteilii TaxID=76759 RepID=UPI000A2F1AF2 ---AVRQRLATLERTHGRTLGLWALETGSGQRL-AYRADQRFAFCSAFKVLLAGAILQRNE -AEPGLLAQHIDYDAATLVTYSPITQDHLETGMRVADLCAAALQYSDNTAANLLLAQVGGP -AGLTAFARRLGDAVFRLDRDEPTLNTALPDDPRDTTTPLAMGMTLERLLVGKALTVPSRH -QLQAWLEGNTTGASRIRAGVPGDWRVGDKTGTGDYGVANDVAIVWPPGRAPWIVVLFTRG -PDPSSPGDSALIAAAMREVAGAw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter sp. SVU/SVIMS10 TaxID=1476169 RepID=W8TNT7_9GAMM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQAT------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0010BD16F5 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMRLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillaceae TaxID=186817 RepID=A0A1Q8GU40_9BACI --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRQDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTAKALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. K2I17 TaxID=2014743 RepID=A0A246PVG8_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHVDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL6669N2 TaxID=1938807 RepID=A0A3E0C8V3_9BURK ---AIRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD -RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGNAARSNAAIADVGALVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3A9ZZV6_9ACTN ---DLAPEFRRLEAAFDARLGVHAVDTGTGRTV-AYRADERFAYASTFKALAAAALLDRTS ---AAQLDEVVHYTREDLLAHSPVTERHVATGMSLRDLADAAVRYSDNTAGNLILRRLGGP -AGFGESLRGLGDTATDAERYETSLNEGRPGDRRDTTTPRAFATDLRAYAVGDALGREDRD -ILNGWLRGNTTGDGLIRAGTPQGWVVGDKTGSGGYGARNDIAVLWPPDGAPIVLAVMSRR -DAKDAPYDDALIARATRVVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus bombysepticus str. Wang TaxID=1330043 RepID=A0A023PGL4_9BACI ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRKMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGNKLIRAGVPKEWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia farcinica TaxID=37329 RepID=UPI000BF870F0 ---AATAEFAALEQRFGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLADATRAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C1ZZ55_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces africanus TaxID=231024 RepID=UPI000A3A999D -----TARLRELEREHTARLGVYARNLRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITEDNVATGMTVGELCDATIRFSDNAAGNLLLKELGGP -TAITRFARSVGDAVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA -RLTDWLLRNTTSDERFRKGLPADWLVADKTGGGRYGGSNDVGLTWPPDGAPIVLSVLTTQ -PEEDAPADDALVAKTAAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas solaris TaxID=2529389 RepID=A0A558R7B6_9SPHN ----LTARLATIEATTGGRLGVAMLDTATGEAA-GYRADERFPMCSTFKLLVAAMTLHRAG -RLPGTLDAIVPYGAADLIAHSPVTARHVATGLTVRALCHATMTESDNAAANLLLARLGGP -AALTRFVRGLGDRVTRLDRIEPVLNEARPGDPRDTTSPAAMLATMHRLLLGPVLSTPGRA -TLTGWLVANRTGDTRLRAGVPTGWTVGDKTGAGENGTTCDIGIFWPPGRAPILMTAYLTG -ATVPTEARNAALAAAARAVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009ABDB92 ------KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIHYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTRANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGNYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000278B5F5 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRMNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus tequilensis TaxID=227866 RepID=UPI001436FD33 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-SYRPHERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQMGDHVTKANRFETDLNTAIPGDIRDTSTAKALATDLKAFTLDNTLTIDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKAVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000FF8EBE3 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVTHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTRAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYNNTLIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000DEF8B5E -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Albimonas pacifica TaxID=1114924 RepID=A0A1I3FTN7_9RHOB ------DTVRRIEADLGARVGLSIHDTGRGDRW-EHRADERFPMASTFKVLACAALLSRAD -AGAIDPRRTVAIRQSDLLSYAPVTERRVGGEMSLHALCEATMSTSDNTAANMIIDALGGP -PAVARLARGLGDDVTRLDRREPSLNEGAPGDPRDTSTPAAMAATFETLVLGDALSDGSRA -QLVEWLVGNEVGGPLLRAGLPADWRVGDRTGAGGHGTRGIVAVLWPPNRAPLIAVVFITE -TDASMDARNAAIASIGATIAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium grahamii TaxID=1120045 RepID=A0A5Q0CAF9_9RHIZ --dEIDRRIAALEKQIGGSIGVSVIDTQTNISF-GYRETESFPLCSTFKVLAAGFVLARVD -KGEENLERRITYDTDKLVTYSPETGKHVGGDMSVGDLCHAAITLSDNTAANLLLESFGGP -KELTNWLRTFGDASTRLDRWETDLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN -TLVEWMVANTTGGARLRSGLPDGWKIGDKTGTGNNGCAADIAIAWPPGHGPLLMTVYVKQ -ASAPVADINPVFAEVGRIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0003308BFF -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI0008180F21 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G4KTY8_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI001244A09C -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=A0A172YI92_9GAMM --------AREIEQRLEARVGLAIYDTGSNQSW-LYKADERFPMASTFKAFACATLLHQVD -AGGRDLDQTVALAEVDLVPYAPVMEKLVGQRVSLGELCAAAMRTSDNLAANKVLDSIGGP -QGVTAFMRSIGDDTTRLDRWEPDLNQATPGDVRDTTSPAAIATSLRELVLGDTLSASSRA -RLTAWLVENEVGGPLLRSGIPQDWRIGDRTGAGGYGSRGVVAVIWPPEREPIVAAIYITG -TNATMDERNAAIAELGEALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000278AC31 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 67 TaxID=2035207 RepID=A0A2M8YK42_9BURK ----AQMQLAALEQAAGGRLGVAAWRHGGELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMKLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAQQRQ -QLDTWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0D7M6_BACCE --------FVKLEKEYDAKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPEHFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKKNTTGDNLIRAGVPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0ESF0_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLERWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIAR--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0011AA9123 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FAKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3G4RT90_ECOLX ----------------------ALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASVAKIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis quinghaiensis TaxID=464995 RepID=UPI00123AA204 ---ELAREFERLEEEFDARLGVYAVDTGTEEEI-AHRPDERFAYCSTHKAFSAGAVLQRNT ---PEEMEEVITYTEDDLLGYAPVTEQHVDTGMTLMELTDAAVRYSDNTAANLLFEELGGP -DGFEEAMEAVGDDVIEADRVEPGLSEAAPGDVRDTSTPRAMAESLRKFTLGDALPEDRRD -VLTDMLVNNVTGDELIRAGVPEGWEVGDKTGSGGYGTRNDIAVLWPPEGEPIVLAVMSSR -DEEDAEYDNALIAEAAEVVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR9_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEAFPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BEBEE06 -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDIRDTSTPMALATSLQTYALGDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDVKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000C1AD850 -hpDTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLTTK -PARDAAADSPLVAATATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. H1a TaxID=1397276 RepID=UPI00046A49EF -----NQSFVKLEKEYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKKN -FLIDLMKKNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomonospora sp. M2 TaxID=2498135 RepID=A0A4P6Q472_9ACTN ------PELLRLEREFDADLGVYALDTGSGEVV-SFGADERFAYASTHKAFSAGAVLEQTP ---MEGLDRRITYTEEDLLDYAPITEKHVDEGMELRAVIDAAVRYSDNTAANLLFEELGGP -AGLQAALKEIGDDTTHVDRTEPELNEAAPGDIRDTSTPEAMAATLRKYALGDVLPEEKRE -ILVDMLRRNTTGDDLIRAGVPEGWTVGDKSGAAAYGTRNDIAVLWPPEGDPIVMAVMSER -DAEDAEYDDALIAEAAEAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFE4F72 -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALNQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium miluonense TaxID=411945 RepID=A0A1C3UW95_9RHIZ ---DVDKQLAGLEKKTGGRLGVSVLDTETNISL-GHRQEERFPLCSTYKALAAGFVLARVD -QGVEKLDRRVTYGKEVVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESVGGP -AALTSWLRVTGDTETRLDRNEPDVNQAVKDDLRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLINWLVANTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFVEVSKIIVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TMW2_9ACTN ------REFGRLETEFDARLGVFAVDTGTGTTV-GHRADERFAYASTFKALAAAVLLDRTS ---AADLDEVVRYSRSDLVAHSPVTEKHVTTGMRLRDVVDAAVRYSDNTAANLILRRLDGP -DGFQRELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYAVDDALSPEDRD -VLNGWLRRNTTGDALIRAGVPAGWTVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR -DTRDAPYDDALIARATRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. SCN 65-56 TaxID=1660095 RepID=A0A1D2S5C7_9BURK ----------AIEVAGQGRLGVAVLDIASQALS-GHRLDERFPMCSTFKWLAAAHVLQRVD -LGHERLERRVRFGKEVLLPWSPVTEHHVGDGMTVGELCQAAVTMSDNAAANLLLQSLGGP -QGLTRFAREQGDGVTRLDRWEPQLNASTPGDPRDTSSPRAMAGLLQRCVLGQALSPGSRA -QLVRWLRASQTNAQRLGAGLPASWRVGSKTGTGPHGTTNDVGVYWREGRSPIVVVAFLTQ -SGASLARREAAIAQVAKAVF--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus HuA4-10 TaxID=1053206 RepID=J8DRP5_BACCE -----NHSFVKLEKEYDVKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDLRIKYTNKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKQPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. Root1455 TaxID=1736465 RepID=A0A0Q7TTC6_9CAUL -------GIVALEARGGGRLGVSVLDTADGKTF-AYRGDERFAMCSTFKALVAGLVLRRVD -QGLERLDRRIVYGKSVLLAHSPATEKHVGEGMTVGALCEATVTLSDNAAANVLLYTFGGP -PALTAFLRGLGDKVTRLDGYEPELNVVRPGEIHDTTSPNAMLATLRALTLGSTLSPASRR -QLIAWLVANQTGDARLRGGLPAGWKVGDKTGSWGIGTTNDIAVIWPPGRSPLLITAYLSR -STLGNDGRNAVIAEVARLVT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces afghaniensis 772 TaxID=1283301 RepID=S4N2B4_9ACTN -----TARLRKLEREHTARLGVYARNLRTGRTV-AYRAGERFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQDYVTKYSPITEDNVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSIGDGVTRLDRWEPELNSAEPWRTTDTTTPRAIGLSYARLVLGDALEPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAEAAALLA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9PW77_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASIYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDA2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDQQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQI----------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000C34A8B9 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGNIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B3TYI2_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNNIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 2_A_57_CT2 TaxID=665959 RepID=E5WQ45_9BACI ---NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLQRKS ---LEEMNEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP -EGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPEALAASLQKVLIGHFLSEEKRN -ILTEWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR -DSKDAEYDNALIAEAAEMAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5D27F -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNNIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Nitratireductor indicus TaxID=721133 RepID=K2P082_9RHIZ ---AFDRKFIEVEAWLGGRLGVAIEDVQTGQKW-SYRSAERFPMNSTFKAFACAAILARAD -AGKEDLSRRIVFQKEDLVTWSPVTEKHVGGRMTLRELCAAASTMSDNTAANLLIDALGGP -RGWTDFMRSIGDDVSRLDRKEPDLTEGTPGDPRDTTSPDAFLESLKAAALGNVLSPASRS -QFIDWLVDNRVSGSLLRAGVPKDWKVGDRTGAGGHATRGITAIMWPPKRKPIIATIFVTE -TRRSMEDRDAAIAEIGRF----- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C2UFF0_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKALAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSEQVEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKAVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0YYH9_BACCE -----KHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=C7S9Q3_ECOLX -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATM------------------ ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BA71_9BACT ---DFANRILPIEERAGARIGVAALDTGTGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD -EGKENLERFIRYSSQDLLEYAPVTKAHLKDGMTLAALCAAAIEQSDNTAGNLLLDVIGGP -SGLTNFARSIGDQITGLDRKEPELNSAIPGDERDTTTPAAMCADLQRLLLADVLFESSRQ -EFEDWLRHNETGALMIRAGVPQTWSVGDKTGRCANGATNDIAILRPAGRAPILIAIYCIG -STGPADDRAAAIAETARAVVE-- ->[subseq from] class A beta-lactamase n=2 Tax=Janthinobacterium sp. KBS0711 TaxID=1649647 RepID=UPI00110F256D ---AAQTQLATLEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0AJI9_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKTS ---IEDLDQIIKYTSKDLVNYNPITEKFVDAGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYNDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7050C ---TVNHSFAKLEKEFDAKLGIYALDTDKNQTV-TYQSDERFAYASTHKALAVGVLLKKKS ---MEDLNQRILYTREDLVNYNPITEKYVDKGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNKVHPGDTHDTSTPKALATSLQAFALRDVLSIEKRN -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLE-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY61_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIA---------- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=Q6ZY72_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPAGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIA---------- ->[subseq from] Beta-lactamase (Putative hydrolase) n=1 Tax=Bacillus sp. 349Y TaxID=2653176 RepID=A0A653WPG8_9BACI ------ETFANIEDKYDARVGIYAIDTGADRTI-DYRSKERFAFTSTYKALAAALVLKQNT ---MEELEEVITYTEDDLVSYSPITEKYVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQADRYETALNEFTPGDPRDTSTPAALATSLQGFAVGDLLPDDKRK -ILIDWMKGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIIMVIMTRH -DTEDADYDDALIAEVAEVTLE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS149 TaxID=2109332 RepID=A0A2P8B697_9ACTN -----TAAFRKLEREFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -EGLDASLEKLGDDVTRMDRGEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinofusca TaxID=47858 RepID=A0A1C5G7K6_9ACTN -----DHEFRQLEKKFDARLGVYAIDTGTGRTV-GYRADDRFAYTSTFKALAAAEVLDETT ---DAELDRVVRYSADDLVTYSPITQLHVADGMTLRAIADAAVRYSDNTAGNLLLRQLGGP -RKFEKELREVGDKVTDAARYETALNEARPGDRRDTSTARALAQDLRAYAVGDALEPADRD -VLTGWLRGNTTGDELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPNRAPIVLAVLSSR -DEEDAGYDNALIARATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=UPI0007173688 ----WSAQLRVLEKNSGGRLGVGMLDTGSGQHF-DWRGRERFPMCSTFKFLLAAAVLREVE -RGKLDLQKKIPIAKSDLIAYSPVTEPLAGSSASVAQLCEATMTLSDNTAANLLLPLVGNP -AGLTTFLRGIGDPTTRLDRKEPELNSAIPGDPRDTTSPLAMVATMRKLLLQDGLQPASQK -QLTAWLVANRTGDKRLRAGVPKGARVGDKTGTADT-TSNDLAIIWLPERAPILLTCYLTG -STLDGPGRDAIHASVARLVF--- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YN87_9BACT ---DAADQIAAIEARLGGRIGVAGLDTGSGKRV-DYWAEERFPLCSTFKFLAAAAVLKRVD -EKKDKLDRFVSYDAKDLLEYAPVTKAHLGNGMTLGALCAAAIEQSDNTAGNLLLEAIGGP -AGLTNFARDLGDRMTKLDRKEPELNSAIPGDERDTTTPASMLGDICQLLVGNTLSASSRQ -QFEEWLQANETGAAMIRAGIPTNWIVCDKTGRGANGATNDIAIVHPPDRAPILLTIYCVG -STASTNDRAAVVAEVAKVVAESf ->[subseq from] class A extended-spectrum beta-lactamase FAR-1 n=1 Tax=Nocardia farcinica TaxID=37329 RepID=UPI00085C4340 ---AATAEFAALEQRSGARLGVYAVDTTSGAEV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLAEATRAVVT-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2V2H7S5_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2C5AJR6_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTYEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF049BF -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTYEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Rhodanobacter TaxID=75309 RepID=I4VTE5_9GAMM ---QATTQFTALERKHGGRLGVSILDTQSGHRI-QHRAGERFLMCSTFKWLAAAAVLARVD -SGKERLDRRVVYGKDVLLSYAPITSKHVGAPLSVADLCAAAVTLSDNTAANLLLASLGGP -TAITAFARSLGDETTRLDRIEPELNLGRPGDIRDTTTPDAMLSDLHRVLLGDRLSLASRG -LLLQWLRECTTGLDALRAGLPKEWTAGDKTGSGSQGETNDVAIIWPPQRKPLLVTAYYAG -SRAEPAERKAVLAAVGHIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI00077A6014 -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYTLSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=9 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2L1J0S4_ECOLX ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATM------------------ ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. HH106 TaxID=1537278 RepID=A0A1E7VYP5_9BURK ---AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLDRSV -SQPGLLEQLVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMKILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEMRDTASPASMAHSLQQVLLENSLPAPQRQ -QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas endophytica TaxID=2033802 RepID=A0A2N7UC14_9GAMM --------ARQTEARLDARVGLAIYDTGSGASW-LYNADERFPMASTFKVLACGALLARSD -AGYENRNRLVPIVQSDLVTYSPVTEGWLGQEVSLDALCAATMRTSDNTAANKVLEALGGP -DAVTAFLRSIGDEVTRLDRWETELNEATPGDLRDTTTPAAMANSLQRLLLGDALSPSAKA -TLTEWLVGNEVGEPLLRAGIPDDWHIGDRTGAGGHGSRGVVAIVWPPERAPLIAAIYITQ -TEASMEQRNEAIATIGRALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8TZ76_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVINYTKDDLVEYSPVTEKHVDSGMTLGEIVEAAVRSSDNTAGNILLNKIGGP -KGYEKALRQMSDRVTMADRFEAELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNKAPIIIAILSSK -DEREDTYDNQLIAEAAKVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEDA998 -----NHSFVKLEKEYDAKLGIYALDTSTSQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDIRDTSTPKALATSLQAYALGDILSIENRK -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI00086404A9 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTRENLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 / ORS 571) TaxID=438753 RepID=A8HV65_AZOC5 ---DLAQKIAALEARSGGRLGVAVIDTGTGARF-AHRGGERFPMCSTFKFLLAAAVLAEAD -RGHLKLTDMVPITRADLIAYAPEVEKHVGSGMSLSDLCAAAVIWSDNGAANLLLRQIGGP -AAVTRFLRSAGDPVTRLDRAEPELNVVPEGSDMDTTTPDAVADDMVRLVLGDVLVPASRG -ALKDWLIGCRTGDKRLRAGLPKGWTVGDKTGTGPTGTSNDVAIAWPPGRAPLVIASYLTA -SRLDGRGSDAIHADVARAVT--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000016E6C3 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEAIYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFE87D1 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAAGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLITDATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B4B7F49 -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSNERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKNLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIMLAILSNH -EKEDAKYDDKLIADATKIVLD-- ->[subseq from] Class A beta-lactamase n=2 Tax=Agrobacterium TaxID=357 RepID=A0A546YJW3_AGRRH --eDADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAITLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVANTTGNARLRAGLPKEWKVGDKTGTGDNGSYADVAVIWLPDRGPILVVTYVGE -ATAPAKDIEAVFAEVGKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces alni TaxID=380248 RepID=A0A1I1Z2B5_9ACTN ---RTEREFGALEKTFDATLGVFAVDTGSGRSV-AHRADERFAYASTCKALLAGAVLDRSG ---AAGMDRLVRYGAADLVSNSPVTERHAGTGMTLRELCDAAIRYSDNTAANVLFRDLGGP -GRLQEALRALGDRVTRCDRTETDLSDAVPGDPRDTSTPRAMATDLRAYVLGGALPADGRA -LLTDWLRRNTTGATTIRAGVPRDWRVGDKTGTGGYGTRNDIAVLWPPTGAPVVLAVFSRR -AAKDAARDDALIARAAEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium fredii (strain NBRC 101917 / NGR234) TaxID=394 RepID=C3M8I4_SINFN ---DVTKLVAELEKRTGGRLGVAVLDTETNISF-GYRETERFALCSTFKALAAACALARVD -RGEEKLDRRIVFGKDVLLPHSPVTEKHVGGAMTIAELCDAAITISDNAAGNLLLESFGGP -AGLTAWLRSIGDGTTRLDRTEPDLNEASFGDPRDTTTPAAMLETLGKLVFCSALSEASRQ -QLVEWMVANTTGNARLRAGLPKSWRIGDKTGTSSTGAVSDIAFAGPEGRGPILIAVYTGE -AKLPPAELNPIFAEIARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009D001DC ---MLRAQWAQIERGTGGRLGICLLDSATGKRV-GQREHERFPMCGTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPNGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. 141 TaxID=2056666 RepID=A0A2M9TC78_9GAMM ----ISAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGRLALDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP -EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ -QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE -TDASFEARNEAIASLGKVVQ--- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora purpureochromogenes TaxID=47872 RepID=UPI0004C2E3AC ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---GADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALREVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYALGEALPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVVRAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas cremoricolorata TaxID=157783 RepID=UPI0003F57C85 ---SAASRFEQIERQHGITLGVFALDTGSGRQL-GYRAEQRLPMCSTFKVMLAGAVLQRSQ -AEPQLLARVIRYPASALVVYSLVTERHVEQGMSVAELCAAALQYSDNTAANLLLELLGGP -AELTAFARRVGDPVFRLDRIEPDLNSALPDDPRDTSSAQAMALSLQRLALGDALDHAGRG -QLQTWLKGNTTGAKRIRAGVPVGWTVGDKTGSGDYGVANDVALLWPAGRAPWVLAVLSRS -AEAKAAWRDAALAEATGVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Sporosarcina globispora TaxID=1459 RepID=A0A0M0G6E8_SPOGL ----TDQKFKQLERDFDARLGVYAYDTGSKKTI-AYRSNERFAYASTFKPLAAAILLEKKS ---LEEMDEIITYKSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLMLEELGGP -EGFETALKEMGDSVTKPSRFETDLNEAEPGDIRDTSTPKELAASLQKSLMGDLLPEEKQS -ILTDWMRGNATGDPLIRAGVPSGWEVADKSGAGGYGTRNDIAIVWPPNREPIIMAILSSR -DSKDAEYDNALIAEAAEMTIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A380YDF4_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEAIYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2C9YQF6_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGSATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEF5FB2 ---ATYKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TNKLNEVITYTKDDLVEYSLVTEKHVDTGMTLGEIAEAAVRTSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKALTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces oceani TaxID=1075402 RepID=A0A1E7KJ86_9ACTN ----YAKEFKKLERKYDARLGVYVRDTGTGEEL-TYHADQRFAYASTFKALAAGAVLDEYS ---PKEMEKVVHYSEDDLIEHSPITEKHVDTGMSLRALSAAAVRYSDNTAANLLFDALGGP -KGLDAKLAALGDDVTQMNRYEPELNEATPGDPRDTTTPRAFAKDLREYVLGDVLPKDDRA -LLRKWMRTNVTGDALIRAGVPDDWTVADKSGGGGYGTRNNIAIVRPDEGAPLAVSILSSR -DTKDAEYDDALIAEAASVVADQf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011459054 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHIDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8IWB2_BACCE -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS075960 TaxID=2034282 RepID=A0A2B4NIJ3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS654 TaxID=1506995 RepID=UPI000517A6D8 -------DFEKLEREFDARLGVYAIDTGTGHEV-THNDRDRFAYNSTFKALQAAAVLSTYS ---LDGMDERVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. NCPPB 1128 TaxID=1775876 RepID=A0A0J6IQW9_9XANT ---TLQQRLADIERRSGGRLGVSLLD-GSGARLgGQRQDERFPLCSTFKFLLAGAVLQRID -RGELSLERRVPVRKADLLGNAPVSERHVGGTLSVAELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQIQLDRNEPGMNDFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ -RLIDWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDAALKAVAQAVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus bataviensis TaxID=220685 RepID=K6DNC2_9BACI ---QIHREFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS ---IDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLREVAEAAVRYSDNTAGNLLLEKLGGT -EEFETALRKIGDHKTQVDRYETDLNSAVPGDTRDTSTPKALATSLKAFVVSDLLPTEKRT -ILTDWMRGNATGDALIRAGAPTGWKVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATYDNTLIAEAAKIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=UPI0012E7D0DE -------------------------TVPSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium versatile TaxID=2488639 RepID=UPI000D61A897 --pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP -QELTIFLRKTGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -SQATIEERNKQIAEIGTSLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora TaxID=1873 RepID=UPI00083E20CE ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALREVGDSVTRPARTEPDLNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD -LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR -GSRDAKPDDTLVAQAARATV--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora rectivirgula TaxID=28042 RepID=A0A073AY97_9PSEU ----AREEFSRLERDFDARLGVYAVDTATGREV-AYRADERFAHASTFKALAAGELLRRNS ---LEELDRTITYSRDDLVTYSPITEKHVDSGMPLREVIAAAIRHSDNTAGNLLLRELGGP -DGFTAALRRIGDTTTRADRFETDLNETAPGDPRDTSTPRALATSLRAYAVDDVLPADKRA -VLNEMLRTNTTGDALIRASAPAGWQVGDKTGAASHGTRNDIAVVWPPERAPIVLAVLSDR -EAEDADYEDALIARAAAVVFE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FA84_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRILLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium agaricidamnosum TaxID=55508 RepID=A0A3G2E3Y2_9BURK ----AHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLEQLVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMKILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEMRDTASPASMAHSLQQVLLENSLPAPQRQ -QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. HH107 TaxID=1537279 RepID=UPI000873BE4E ----AHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLEQLVRYEKKELVTYSPITEKHLADGMRVAELCAATLQYSDNSAANFLMKILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEMRDTASPASMAHSLQQVLLENSLPAPQRQ -QLATWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPPSGAPLLIAVYYTR -EQKNADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD115 TaxID=1053230 RepID=J8H3A6_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEAVYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7XMH1_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus subtilis TaxID=1423 RepID=BLAC_BACSU -----NKKFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRM -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A654MTJ3_BACIU -----NKKLVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDTNYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009947615 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILKEIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BED7C5B -----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008589B87 -----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0ACEA ---DVDKQLGDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGAEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPNVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVSRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CNZ297 TaxID=2572905 RepID=A0A559VES7_9ACTN -------ELAALERRSGARIGIFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARATV--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL17N1 TaxID=1938798 RepID=A0A495G2Y4_9BURK ---AIRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD -RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGKAARSNAAIADVGALVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia ribeironis TaxID=1247936 RepID=A0A1N7RL64_9BURK ---AIRRRLAQIEAESGGRLGVSIVDTTSSLHA-GWRADERFPMCSTFKLLAVGAVLTRVD -HGAEDLQRRVVFSLNGIVPNSPATSRHARELMSIAELCKAALTLSDNAAANLLLASFGGP -AALTAFARSLGDGITRLDRIEPTLNEATPGDPRDTTTPNAMLGNLRALVLGEQLSSASRA -QLLGWLADNQTGGARLRAKLPNDWRVGDKTGTGEHGTANDIAILWPPGRGPVLVTVYLTG -TDGDAARSNAAIANVGALVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DF2E7EF ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQAT------------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces qaidamensis TaxID=1783515 RepID=A0A143CCR0_9ACTN -----TARLRDLEREHTARLGVYARNVRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQAYVTKYSPVTKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSTGDPVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGDALEPRDRA -RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas nasturtii TaxID=1843581 RepID=A0A3E1KNX3_9XANT ----LRARWAEIERGTGGRLGIGLLDSATGWHI-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIHTADMLAHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -AGLTAFLRGIGDAHTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPEGAPLLLTTYLNG -AKVDAAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus luti TaxID=2026191 RepID=A0A1K0BGJ4_9BACI --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNA ---MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEQALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSK -DEKEATYDNRLIEEAAEVVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=A0A1Q4W413_9ACTN -----HDRLMELEQKYDARLGVYALDTGTGTVI-AHRADERFAFCSTFKGLAAAAVLHHNP ---LSHLDEVITYGKDDLMKHAPVTARHVTTGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP -ARLTAYARELGDTVTRIDRIEPAISEATPGDPRDTTSPRAFGTNYRKMVLGSALPAEKRA -FLRDLLLRNTTGAQRIRAGVPRGWTVADKTGTGDYGTLNDIAIVWPPKAAPLVIAIMSNR -AAQDAAYHQAVIAEAAAHVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0004E29A5D -----NKKFVQLEKKFDARLGVYAIDIGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRM -ILTDWMRGNATGDELIRAGTPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2H3NNM8_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDHFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGIRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus phasianinus TaxID=2017483 RepID=A0A220U7A1_9BACI ---TLKDEFVKLEKEFDARLGVYALDTGTNQTI-TYRSDERFAYTSTHKALAVGALLQQKS ---IADLDERIMYTRDELVNYNPITEKHVDTGMTLKELCEAAIRYSDNTAGNLILEQLGGP -SGFKKSLREIGDDVTNPERVEPKLNEVKPGETHDTSTPKALATSLQAFTIGDALPAKKRS -LLTDWLKESTTGDTLIRSGVPKGWEVGDKSGAGSYGTRNDIAVIWPPKGEPIVLAVLTSR -DKEDADYNDKLIEQATKQVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A7ZK41_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDAKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000F47763D -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEIIHYSKDDLVTYSPITEKHLETGMSLKEILEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKTLATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02959 TaxID=2020330 RepID=A0A2M9M510_9ACTN -------EFKELERKYGARLGVYAVNTGNGREV-AFNADERFAYASTFKAFAAGAVLRKYS ---LSGMDKVIKYSRSDLVDYSPVTEKHVDTGMTLSDLCDAAVRYSDNTAANLLFDALGGP -KGLAAALAETGDTTTKVERREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE -QLTQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR -GTKDAAYDNKLIAEAASVAT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 46 TaxID=1777322 RepID=A0A2S6WJB8_9ACTN -----TARLRELEQEHTARLGVYARNMRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQAYVDAHSPVTENHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSTGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDVLEPRDKA -RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTR -SEEDAPADNPLVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0014281BF7 ------DEFADLEKAFDARLGVYAIDTETGRTV-EYRADERFPYTSTFKALAAAAVLEATT ---PADLDHRISYIRADLVRNSPVTEQNVDRGMTLRDLLDAAVRYSDNTAGNLLFDQLGGP -KGLEQKLRGIGDQVTQMDRTEPELNTAVPGDTRDTSTPRALATDLRSYALGNVLPADDRA -LFVEMLRTNTTGGELIRAGAPSDWLVGDKTGGGEHGTRNDIAVVWPPNRAPIVLSVLSTR -LQADATYDNALIARAAKAALTAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MMG1533 TaxID=1415546 RepID=A0A0M9YSL0_9ACTN --kSLTARLRRLENRHGARLGVFAHNLSTGRTV-RHRADERFPVCSVFKTLAAAAVLRDLD -RHGEVLARRIHYTAADLVSGSDQTRKHLATGMTIAELADVAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPVTRLDRWEPDLNSAEPWRETDTTSPYAIGRTYGRLVLGDALNRRDRS -LLTHWLLNNTTSDKRFRAGLPTTWTIADKTGSGSYGTTNNVGIAWTDTGAPVVLSVLSTQ -PDQDAAWDDALVARTAALLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF77A25 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTVQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A516NX53_9NOCA ------DSFAAMESERAARLGVYAVDTGSGRTV-AYREGERFPMASTFKGLACGALLRDHP -LSTGFFDQVIHFSRDELVEYSPMTEQRVDTGMTVAELCEATITLSDNTAGNKVLELLGGP -AGFTAFLRSIGDEVTRLDRWETELNSAVPGDERDTTTPAALAADYRALVLGDVLGEPERA -QLKSWLVANTTGDQRIRAGVPADWTVGDKTGSPAYGGALDVAIAWPPGLAPIVIAVLTTK -SEPDAEPDNALVVDATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF5340B -----RHSFVKIEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI00055422E1 ---DVDKQLEDLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKEVVVTYSPETEKHAGTDMTVAELCGAAIMLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKGDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLVYWLIGNTTGNNRLRAGLPKEWKAGDKTGTGDNGSFADIAVIWPPDRGPILVTTFVAE -GTAPAKDIEAVFAEVGKIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001066B251 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLETGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIEWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella antibiotica TaxID=190195 RepID=A0A4R4ZXY3_9ACTN -----NKAFQQLEKQYAARLGVFALDTGSYKTV-SYRANERFAYASTFKSLACGVLLSQAE -----DLDKLIRYTQADLVSYSPITEKHVDTGMTLRELCDAAIRFSDNTAANLILVELGGP -AGLQRALRKLGDGISNVNRNEPTLNEAKPGDKRDTTTPRQLATSLQKFTLGRALPPAKQK -ILNDWLLTNTTGDKTIRAGVPAGWKVGDKTGTAGYGGRNDVAILWPPNRAPIMLAVMSTK -GVKDAPTDDALIAAAAREAVK-- ->[subseq from] Beta-lactamase n=2 Tax=Ensifer TaxID=106591 RepID=W8IFS5_ENSAD ----VDTRLAELEKRTGGRLGVSVLDMETNVSF-GRRESERFAMCSSFKTLAAGFALARAD -QGAEKLDRRIVVAQKDIVAHSPVTEKHVGGEMTIAELCAATLTTSDNAAANLLLENFGGP -PALTAWLRTIGDETTRLDRNEPALNEAKVGDPRDTTTPAAMLETLGNLAFGPVLAEASRK -LLIEWMVANTTGDLRIRAGLPKAWKVGDKTGTNGNGAASDIAIVWPEGRGPLLIAVYIAE -ATAPLAELNTVFADVGRMAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDC7B7A ---DVDKQLGDLEKKIGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDKVVTYSPETEKHAGTDMTVAELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSYADIAVIWPPERGPVLVTTFVAE -ATAPAKDVEAVFAEVSRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000B235957 -----AAALARLEDGLNGRLGVFAIDTASGAAL-GHRASERFPICSTFKAILAGAVLARGV -REPGLLDERVRYTKADLIAHSPVTGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP -EALTAQARAWGDSTFRLDRWETELNSALADDPRDTSTPEAMARLLRTLAVDDGLPTAQRA -RLQDWLRGNTTGGARIRAGMPAAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL -DAQDAKPRDDVIAAAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A562DEV8_MICEC ----ADRSFGALEARFAARLGVFAIDTGSGATV-THRADERFAYASTFKALVAAALLDATT ---PAQLDRVVRYTRADLLAHAPVTREHVGTGMSLRDLADAAVRYSDNTAANLILAELGGP -AGLARHLRALGDRTTKPVRTEPALNQATPGDERDTSTPRALATDLRAYVLGDALDAGDRA -LLTDWLRRNTTGDALIRAGVPAGWTVGDKTGTAAYGTRNDIAVLWPPEGTPIVLAVLSSR -AAEDAEHDDALIAEATRVTLD-- ->[subseq from] TEM beta lactamase n=2 Tax=Pectobacterium TaxID=122277 RepID=A0A221T4I2_PECCA --pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP -QELTIFLRKAGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -SQATIEERNKQIAEIGTSLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02959 TaxID=2020330 RepID=A0A2M9M7D2_9ACTN -----EGELRDLEQRYAARLGVYARNVRTGQVV-AYRAQERFAMCSTFKAVAVAAVLRDQA --RCAPLDKVIHYPPADILPNSPKTKEHVDTGMAVRDLCAAAIQYSDNAAANLLLRQIGGP -DGLTRFFRSIGDPVSRLDRWETELNTAIPGDPRDTTTPEAIGTSYGQLTLGRALAPADRE -QLVDWLKGNTTSAERFRAGLPHGWIVGDKTGTGDYAAANDIGVAWTTRKTPLVLAVLSSK -DTKDAPVDNALIAEAARILA--- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobiales TaxID=356 RepID=A0A1G5P1M3_AFIMA --dELMRTLSEVEQRLNARLGAYVLDIETGREW-AQRADERFPMCSTFKLLACGAVLAKVD -MGEEDLERRIIFEEKDLVTYSPVTKEHVGGEMTLADLCVAAMTQSDNTAGNLILDSLGGP -PAITSFARSIGDQVTRLDRRETELNEATPGDPRDTTSPRAMGRDAQTLLVKGSLSDRSRL -YLKRWMCTNKTGDEKLRAGLPGDFLVGDKTGGGGNGTMNDVAVIWPSGRKPIIASIYLTE -SGASFDERNAGFAEIGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00103C8355 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDTNYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B55A0F -----NKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLEKNS ---IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI0009FF3CB6 --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNA ---MDKLNEVIKFTKEDLVEYSPVTERHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEQALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSK -DEKEATYDNRLIEEAAEVVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Labrys sp. WJW TaxID=1737983 RepID=UPI0009EE0E8D ----FAGAIRRIEGEVGGRLGVASLDLKSRVRL-VYRPDELFPLCSTFKLLVAAAVLARVD -QRHERLSRQVPIEAARLLPNSPITARHAGGHLTLAELCEAAITVSDNLAGNLLLEAVDGP -AGLTRYLRSIGDSVSRLDRWEVELNESLPGDPRDTTSPAAMLADLQRLLVGEALSPSSRS -QLTAWLKASRTGDTRLRAGLPAEWAFGDKTGTGERGSTNDVAIAWPPGRTPLLIAAYLTG -TTAAADRRNAALAAVAKAVVEH- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI00114175C3 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKHK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-45505 TaxID=2011009 RepID=UPI000C232C27 ----IDEEFAQLEGEFDARLGVYAIDTGKNQIV-EYNPDERFAFASTFKVLAAATLLKQNE ---IKDLEKVVTYSKEDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -NKLEQALRDIGDDVTEPERYETELNEFTPGSESDTSTPRAMATNLKKVALDDFLPNEKRE -LLIDWMKGNATGDALIRAGQPEEWVVGDKSGAASYGTRNDIGIVWPPNREPIVIAVMSRH -DTQDAEYDDELVAKAAEITRNAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0011A4DABE ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI001361FCF0 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIHYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDTNYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A4R6HHR1_BACIU -----IKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase FAR-1 n=2 Tax=Nocardia farcinica TaxID=37329 RepID=BLAC_NOCFA ---AATAEFAALEQRFGARLGVYAVDTTSGAVV-AYRADERFGMASTFKGLACGALLREHP -LSSGYFDQVVRYSREEVVSYSPVTETRVDTGMTVAELCHATITVSDNTAGNQILKLLGGP -AGFTAFLRSLGDEVSRLDRWETELNEVPPGEERDTTTPAAVAANYRALVLGDVLAEPERA -QLRDWLVANTTGDQRIRAGVPAGWTVGDKTGGGSHGGNNDVAVAWTETGDPIVIALLSHR -TDPAAKADNALLAEATRAVVT-- ->[subseq from] Beta-lactamase n=4 Tax=Xanthomonas vesicatoria TaxID=56460 RepID=A0A1L5QQS7_9XANT ----LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKLSLAQPVKIRASDMLSHAPVTERHVGGALSVGDLCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLHTLLLGDALQPASRT -QLTDWMIDNRTGDDCLRAGFTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD115 TaxID=1053230 RepID=J8JAA9_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQKITYTHEDLSNYNPITEMHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. IHB B 7164 TaxID=1827146 RepID=UPI0007CDA4C3 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA -LLTDWMKRNTTGNALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0006A85C43 -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNC -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL9I2N2 TaxID=1938809 RepID=A0A4R1MLH3_9BURK ---AIRRRLAEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKVLAAGAVLARTD -RGEEDLQRRVVFSQRDVVSNSPATSKHTSELMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARGLGDGITRLDRNEPTLNEAIPGDPRDTTTPNAMLGNLRELLLGERLCSSSRA -QLLAWLAANETGGARIRAKLPMEWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGDAARSNAAIANVGALVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C3T9A4_BACMY ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITGKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWSPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4V2WBQ7_BACTU -----NDSFAKLEKEYNAKLGIYALDTGTNQTV-SYHANDRFAFASTSKSLAAGALLRQNS ---IEALDERITYKREDLSNYNPITEKHLDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIDDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWELADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIAEATKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A5D4PGH2_BACIU -----IKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas phaseoli pv. dieffenbachiae TaxID=92828 RepID=A0A1V9GVN6_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADGDPRDTTTPAAMAVTLRTLLLGGALQPASRK -QLTAWMIDNRTGDDCLRAGLAADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora globosa TaxID=47863 RepID=UPI0004C0D9ED -------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSR -DSRDAEPDDALVAQAARATV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces corynorhini TaxID=2282652 RepID=A0A370BI09_9ACTN ------DAFKGLESKFDARLGVYAVDTGTGEEV-AYNDGERFAYASTFKALAAGAVLREHA ---PDGMDQVVRYSEKDLVSNSPVTEKHVATGMTLAELCDAAVRFSDNTAANLMFDHIGGP -KGLNTVLKELGDDVTRMERREPGLNDWVPGQKRDTSTPRALAEDLRAFVLGDALGAAERA -RLTHWLRTNTTGDELIRAGVPQGWVVGDKTGAGGYGTRNDIAVVWPSAGAPVVMAILTNR -TEKDAEYDNKLIAEAASVIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD6F0A6 ---EIDRRIGALEKRIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGQENLERRVVYDKAQLVAYSPETEKHVGGEMSVGDLCRAAITLSDNTAGNLLLESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDVAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIQWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFGEVGRIVAE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFC497E -hqATYKDFSQLEKKFDARVGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -ILTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPSNRAPIIIAILSSK -DEKEATYDNQLIAEATEMIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. Root480 TaxID=1736542 RepID=UPI0007010ED9 ---DATAQFTELERKHGGRLGVSILDTQSGRRI-QHRAGERFLMCSTFKWLAAAAVLARVD -SGRERLDRRVVYGKDVLLDYAPVTSKHVGAPLSVAELCAAAVTLSDNTAANLLLASMGGP -TAITAFARSLGDETTRLDRIEPELNLGSPGDIRDTTTPDAMLADLHRVLLGNRLSAGSRD -LLLQWLRGCITGLDAIRAGLPANWTASDKTGSGSQGETNDVAIIWPPRRKPLLVSAYYAG -SHAEPAERKAVLAAVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A431QJU2_9BRAD ---DLQQTIAGIEADCGGRLGVALLDSASGALS-GHRLDERFPMCSTFKALLAAAILTKVD -AGAEQLSRRIPIAQADILSYAPVTKQHVGTSLSVGELCEATVTLSDNTAANLLLATLDGP -AGLTRTIRGFGDAITRLDRIEPGLNESIPGDPRDTTTPAAMAQTLAKLTVGNTLSAASRD -VLNGWLIGCKTGAAKLRAGLPAEWRVGDKTGAGDHGSSNDVAVIWPAGRGPVIVTSYLTE -TKASDDRRNAAHAAVGRAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00064C7D04 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BECDEE6 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -AEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MD99_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAMLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQI----------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF95AEE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITENHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Labrys neptuniae TaxID=376174 RepID=A0A5C1WBW5_9RHIZ ---DFAAAIGRIEGEVGGRLGVAALDLKSNTRL-AYRPDELFPLCSTFKLLVAAAVLAQVD -QGREQLSRMVSIEAARLLPNSPTTARHAGGQLSLAELCEAAITLSDNLAGNLLLEAVDGP -AGLTRYLRSIGDSVSRLDRWELDLNESLPGDLRDTTSPAAMLADLKVLLVADALSPSSRH -QLNAWLKANRTGGSRLRAGLPDGWEVGDKTGTGERGSTNDVAIAWPPDRPPLLLVAYLTG -TTAPADRRNAALAAVARVVMEH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BFCC600 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLEQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HUCO-GS316 TaxID=2692198 RepID=UPI00136A5D50 ----VTARLRALEAQRGARLGVFASNLATGRTV-AHRADERFPVCSLFKTLAAAAVLRDLD -RHGETLARRVHYTADDLVENSPRTEEHLAEGMTIAELADAAIRYSDNTAGNLLLRELGGP -PAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALNRRDRA -LLTHWLLNNTTSDNRFRAGLPRTWTIADKTGGGFYGTNNDVGIAWTEDGTPLVLAVQTTF -ADEDAPYDHALIAETAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4382C1 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -GKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar navarrensis TaxID=339658 RepID=A0A243ACT7_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKALQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. ok061 TaxID=1761766 RepID=A0A1H6BP99_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPQGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI0005AAA98B ---SVRDALAALERTSGGRLGVCAIQTCKPREI-RYRADERFPFCSTFKVVLAAAILARSL -DVPGLMQRRIRYTKHDLAHYSPVSSKHVKDGMTVAELCQAAIQYSDNTAANQLMKVLGGP -QAVTAYAHATGNAAFRLDRWETELNTAIPGDLRDTSTPAAMARTLQTLTVGQALPSAQRD -QLVTWLRGNTTGARRIRAGVPADWQVGDKTGTGDYGTTNDLAILWPPGRAPVMLAVYFTQ -REPKAKARDDVIAAAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A162UZP3_BACIU -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDEMIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FAKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SS1-1 TaxID=2651869 RepID=UPI0012502DE2 ---DVRARLRELERGHGARLGVFAHNVATGRTV-AHRADERFPVCSLFKPLAVAAVLRDLD -RDGEVLARRIHYTEADLVDNSDVSRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP -TAVTRFARSIGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGRSYARLLLGDALDARDRA -RLTHWMLHNTTSGNRFRAVLPPPWTVADKTGGGSYGANNDAGIAWTESGVPLVLAVMTTR -PEQDAAYDHELIAEATRLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0013888174 -----DNSFAKLEKEYDAKLGIYALDTGTNQTV-FYRSDDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTISERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKTVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces xinghaiensis TaxID=1038928 RepID=UPI0002D5FA34 ---EVSRRLRALESEHGARLGVFARNLDTGETV-VRRADERFAMCSLFKPVAAAAILRDHD -RRGEFLARRIRYSDTDLVDHSPVTEDHVAQGMTVGELCDAAIRFSDNTAANLLLRELGGP -RAITRFCRSVGDRTTRLDRWETELNSAEPWRVEDTTSPRAIARTYTRLIVGDTLPPADRE -RLTGWMLANTTSGERFRAGLPAGWDLADKTGGGHYGTNNNAGVAWTPDRTPIVLTVLTTK -PDPDAAPDNELIAETAGLL---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8ERS9_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDHFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] SHV family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D749B7C ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAVITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARATTTPASMAATLRKLLTSQRLSARSQR -QLLQGMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase CTX-M-27 n=1 Tax=Lysobacter gummosus TaxID=262324 RepID=A0A0S2GBW2_9GAMM ---DWNARLRALEKPTGGRLGVAAIDTGSGQSM-QWRGDERFRMCSSFKYLLAAAVLRQVE -LGKLTLDRKVPITAADMISHAPFTQPLVGSSATVAQLCEATTTLSDNPAANLLLPLVGGP -QGLTRFLRDIGDTVTRCDRTEPELNRGAADDPRDTSSPLAQVATMRALLLGDALKPASRE -QLTAWLVANKTGDKRLRAGLPAGVRVGDKTGTAGE-ANNDVGIVWPPGRAPILIVSYLQT -AKLDDAARDAVHAQVARLVYSAw ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY55_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. LHW51205 TaxID=2248752 RepID=UPI000DE97531 ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALRDVGDRVTRPVRTEPELNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD -LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR -GSRDAKPDDTLVAEAARATV--- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus vortex V453 TaxID=715225 RepID=A0A2R9T2A0_9BACL -------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS ---MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP -DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT -LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPTVIAILSSR -DTPDATYDDALIAQAAKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Pleomorphomonas TaxID=2627136 RepID=UPI00141DFCFF ---KADDDFAKLEKQSGGRLGVAAIDKASGTRI-AYRADERFAMCSTFKFLAAAAVLSRVD -KGELKLDKSIAYGKDDLLSYAPVTKEHVAEGLTLEALCAAAVGVSDNTAANLILKEIGGP -AGWTAYARSLGDATSRLDRTEPELNTAVSGDARDTTTPEAMLGNLDAVMIGDALKEASRD -KLEDWMVSGTVTGPLIRSGVPKTWQVADKSGSGANGTRNDIGVLYRPNTAPILAAIYTTG -SPLDMKGQNKVIADAAALIAARf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A1S1YIN9_9BACI ---NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLQRKS ---LEEMNEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP -EGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPEALAASLQKVLIGDFLTEDKRN -ILTEWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR -DSKDAEYDNALIAEAAEMAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. M21 TaxID=1155617 RepID=A0A2S9XQ52_9BACI --qATHKDFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRNSDNTAGNILFNKIGGQ -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILREWMKGNVTGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVWPSNRAPIIITILSSK -DEKEATYDNQLIAEATEVIVNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0G8CQW8_9BACI -----NQSFAKLEKEYDTKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLHKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI001164741F ---DTRARLRELEARHGARIGAFAYNLRTKATV-HHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASVLA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q84H50_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQA-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI00119E01C6 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILKEIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIILAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011553F07 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTVWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T6T-1 TaxID=1100828 RepID=A0A1A9CGE5_9ACTN -------AFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus paramycoides TaxID=2026194 RepID=A0A1J9VQ91_9BACI ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP ---INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP -KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKDFTVGNALPADKRK -ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DEKEATYNNELIAQAAEVVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00048B333E ---DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP -KGLGALLAELGDDVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDNWSVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR -DGEDDAYDNRLLAKAAAVVVR-- ->[subseq from] Beta-lactamase n=2 Tax=Paracoccus saliphilus TaxID=405559 RepID=A0A1N7PHH9_9RHOB -----TDRVIEAEQKLQARVGYHMVDLTSGKAT-GYRSDERFPMLSTFKVPLCAAVLARVD -AGEEELDRRIGYASGDLVEYSPVTEQHVGEGMTLSALCDAAITMSDNTAANLLLETIGGP -EGLTTFLRATGDQVSRLDRWETGLNEALPGDPRDTTTPRAMVSTLHRLLFGDALSEAARK -ILITWMENNLVADDLIRVSLPHGWYIADKSGAGARGARAIVGVLGPEDRPERIVAIYMTE -TSASIEARNAEIAKIAKVIVTNw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces qaidamensis TaxID=1783515 RepID=UPI00099FE57D -----TARLRDLEREHTARLGVYARNVRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQAYVTKYSPVTKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSTGDPVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGDALEPRDRA -RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2Q5_9BACT -------AAQQAETELNARVGLAIHDTGSGTSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTAFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMASSLHELLLGDTLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -SDASMEQRNAAIAAIGAALAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0Y5_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVNSLHALLLGEALSPAAQT -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI000557DFEC ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAIMLSDNTAGNLLLQSFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLVYWLIGNTTGNNRLRAGLPKEWKVGDKTGTGNNGSFADIAVVWPPDRGPILVTTFVAE -GTAPAKDIEAVFADVGKIVT--- ->[subseq from] Inhibitor-resistant carbapenem-hydrolyzing class A beta-lactamase KPC-52 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A650DIB9_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARYTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. MYb209 TaxID=1848605 RepID=A0A2S8UQ93_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGFYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF8A5BB -----HNSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF7B20D -----NQSFAKLEKEYDAKLGIYALDTGTNQIV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. Leaf148 TaxID=1736275 RepID=A0A0Q5JBF9_9XANT ----LRAQWAEIERGTGGRLGISLLDSATGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKLPLAQPVKIGASDMLSHAPVTERHVGSALSVGELCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAVAV---- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001155642D --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTGTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Uncharacterized protein n=2 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=A0A261R007_9BORD -----AALFAGLEKAHGRRLGLHAIDTGSGNEI-AYRADERFPFCSSFKAVLAAAVLALDA -RQPGVLDRRISYTTHDLASYSPVTQKHAGGDMRVADLCAATLQYSDNTAANLLLHLIGGP -PALTAFARAAGNASFRLDRYETALNTAIPGDPRDTSTPRDMAVLLGRLVLGDALPAPART -MLADWMLGNKTGDRRIRAATPTGWKVADKTGTGDYASASDIGVIWPPGRQPIVLAIYTTA -RDSKAKADENLIAAAARVALQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia acidivorans TaxID=404580 RepID=UPI000A00D8AB -------AFADLEAKSGGRLGVYAIDTGSGKTV-AYRDGERFPIASTFKGVACGTLLRAHP -LSSGFFDQVIHYPASDLVNYSPETEKHVDSGMTVAELCKAAITLSDNTAGNQILQLLGGP -EGLTAAIRALGDPTTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDALAEPERA -QLKSWLLANTTGGKRVRAGVPADWTVADKTGTGDYGAALDAAIVWPPNHAPVVIVVQTAK -PDQHAEGDNAMIAEATKLAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. Rc5 TaxID=1920666 RepID=A0A1S8XM44_9ACTN ------AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS ---EAELDRVVRYDRAELVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG -VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR -DAKDAQPDDALIAEAARVTID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0007DAF54E -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITKKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinocorallia populi TaxID=2079200 RepID=UPI000D086F52 ------TALRRLEKRFGVRLGLWAADTGTGRSL-GHRQDERFAMCSTFKTYAVAAVLKAHS -SDSGLLGRRIRFTRADLVPHSPVTENRVDSGMTVAELCHAALLQSDNTASNELLDLLGGP -SAVTSFARSIGDPVTRLDRREPELNDVTPGSLLDTTTPAGMAAGYRALLLGEALAQAERD -RLTRWMRANRTGQDRIRAGLPRGWTAADKTGTGEYAAANDVGVAWSPDGRPLVLAVFSDK -PAKDGTHEDRVIAEATKIAVR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces hygroscopicus subsp. limoneus TaxID=264445 RepID=A0A0S2PBU5_STRHL -----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFYRSLGDAVSRLDRWEPELNTAVPGDPRDTTTPEAIAASLERVTLGRALARADRE -RFVGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTTRRTPVVLAVLSGK -STPDAPVDEALIADAAAVVAR-- ->[subseq from] Mutant KPC family beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A6B7HXV1_ENTCL -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPG---DTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000FFE30FA -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEIIHYSKDDLVTYSPITEKHLETGMSLKEILEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKTLATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Methylocella silvestris TaxID=199596 RepID=A0A2J7TKP3_METSI ---QLHGALADLEQKHGGRLGVAILDTATMRRI-ARRGDERFPLCSTFKFLAAAFVLARVD -RKEESLARRIIYASDVLVAHSPITEKHVAGDLPVGEICKAAVSVGDNTAGNLLLDSFGGP -AGLTAYVRSLGDNFTRIDRRETQLNEAAPGDPRDTTTPLAMLEILHKTVLGTALSAPSRQ -QLMAWLVASTTGGNRLRAGIPTGWRVGDKTGSGENNTTNDVAVIWPPRRAALIVTVYYTE -ARASAVERDSVLSEVGRLVA--- ->[subseq from] CTX-M-1-derivative beta-lactamase n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T1B9L8_9ZZZZ ---ALHAQFARIESQTGGRLGVAMLDTHNRIAA-GYRANQRFPVCSTWKLLAVAALLRQVD -EGHENLDRRIRFSASELVVYSPVTKDHVDATMSLRELCDAALVWSDNTAGNLLLAALGGP -SAITRFARAIGDPVTRLDRTEPALNEATPGDARDTTSPRAMLGDLDTLLLGNALTPPSRA -RLNAWLAASQTGARLLRAGFPTNWRVGDKSGAGEHATRNDVAIVTPPGRAPILVAAYLTG -ATVPMPQRDAALAAVARAIHQ-- ->[subseq from] Beta-lactamase n=1 Tax=Gallaecimonas pentaromativorans TaxID=584787 RepID=A0A3N1PGB4_9GAMM ---DFSRTISDIESQYGGRLGVAAFDSRDGRQL-GYREHDTFAMCSTFKALLAAAVLKKAE -QGQLSLDTELSYGKGDLLDYAPVTAAHVDEGMTVSALAGAAITLSDNTAANLLLAKIGGP -AGLTAYIRSLGDNLTRLDRTEPSLNTNLPGDPRDSTTPTAMVALWQKLLLGKALAPASRQ -QLLAWLKATQTGMAKIRAGLPGGWQAGDKTGSCENGGSNDVAIVWPSGQPPYLLAVYYSD -GLGGSAQKNAAIAAVSQAVAEQf ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011559CBC --qATHKEFSQLEKKFDAQLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEQHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009B47CB4 ------KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 13K301 TaxID=2070367 RepID=A0A2N8TQW5_9ACTN -----TARLRDLEREHTARLGVYARNVRTGRTV-TYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQDYVEKYSPVTEKHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSIGDRTTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALAPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q6ZY59_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVLYLRD -TPASMAERNQHIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mobilis TaxID=2026190 RepID=A0A386V1E6_9BACI -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDRKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377W247_KLEPN ------------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTLGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005947E27 ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Psychrobacter fozii TaxID=198480 RepID=A0A2V4UYP8_9GAMM ---SLVDAVKSAENELGARIGLAVHDLETEQRW-EYRSDERFPLSSTFKTLACANVLHNVD -VGQEKIDRVVRFSKSNLVTYSPVTEKHVGKKMSLGELCQATLSTSDNSAANFILQAIGGP -KYLTQFLRSIGDDTTRLDRWETELNEAIPKDKRDTTTPMAMITTLEKLMLGDTLSTESRQ -QLQSWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPGRKPVIAALYITE -TDASFEDRDAMIAKIGTEIAK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI001155637F --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEVAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCFC17 ----ADVRLATLEKATGGRLGVSVLDLAMNISF-GRRQEERFAMCSTFKMLAAACILARVD -NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP -EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKVLLDDALSEKSRD -QLTAWLVGNKTGDKRLRAGLPKAWTVGDKTGTSATGAIGDVAIVWPSPNRPILVTAYIAE -TTKPAKELEYIFAEIGKMV---- ->[subseq from] Beta-lactamase n=4 Tax=Xanthomonas TaxID=338 RepID=A0A0G8LHR9_9XANT -----GARWAEIERGTGGRLGIGLLDSATGKHF-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -QGLTAFLRGIGDTQTRSDRHEPEMNQFAAGDPRDTTTPAAMALTLRTLLLGDALQPASRK -QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTTYLNG -ASVDSDARDAALKAVAHAVASY- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_331 TaxID=1969379 RepID=A0A328MGK3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYETRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI00142FD08C ---ELREAWAGIERRSGGRLGICLLDSATGRRI-GQREDERFPLCSTFKFVLAAAVLQRVD -KGELTLGKRVKIRAADMLEHASVTERHVGGSLSVAELCRATMIHSDNPAANLLFPLVGEP -AGLTAFLRGIGDAHTRSDRHEPEMNRFAPGDPRDTTTPEAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDTCLRAGLPRGWKIGDKTGSNGSDTRNDIAILWQPGRAPLLLTAYLNG -ATVDAAARDAALKAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0002798A14 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFTSTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI001244936B --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-PYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=A0A6C1VV15_BACLI --tEMKDDFAKLEEQFDAKLGIFALDTGTNQTI-THRPDERFAFASTIKVLTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASIRYSDNAAQNLILKQIGGP -ESLKKELRKLGDEVTNPERYEPELNEVNPGETQDTSTARALATSLQAFALEDQLPSEKRE -LLIDWMKRNTTGDALIRAGVPEDWEVADKTGAGSYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAAATKVVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A1B1L842_BACTU -------SFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQDLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKRA---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9AZ20_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP ---INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP -KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKDFTVGNALPADKRK -ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DEKEATYNNELIAQAAEVVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A2E9BNJ6_9BURK ---DAEARLAALERDCGGRLGVHALDTASGARI-AHRGNELFPMCSTFKLMLAAAILQRGX -QEPALLERRLSYTRAHLXPXSPITEKHLADGMTVAELCAATLQYSDNAAANLLXHQLGGP -AGVTAYARSIGDTVFRLDRWETELNSAIPGDPRDTTSPAAMAASVQRLVLGDALAAPQRS -RLEAWLRGNTTSKERFLAGVPAGWAVGDKTGAGDYGTNNDVGVLWPASGAPLVLAVYLTF -PGKGAKTRNDVVASAVRIVAN-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus cereus group TaxID=86661 RepID=J8LPX4_BACCE ------HAFAKLEKEYNAKLGIYALDTSTNQTV-AYHADDRFAFASTSKSLAVGALLRQNS ---IEALDERITYTREDLSNYNPITEMHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRKMGDTVTNSERFEPELNEVNPGETHDTSTPKAIAKTLQSFTLGTVLPSEKRE -LLVDWMKRNTTGNKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLSILSNH -DKEDAEYDDTLIADATKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A9A424_BACCE ---TTNHSFVNLEKEYDAKLGIYALNTGTNQTV-TYRSDERFAYASTHKALAVGVLLQKNS ---IEDLNQRIKYTSKDLVNYNPITEKYVDSGMTLKELADASIRYSDNTALNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSSPKALATSLQTYALGDILPIEKRD -FLIDLMKRNTTGDNLIRAGVPKEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AEEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2T0DVY3_9BACI -----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2S2_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RLB3-6 TaxID=2594457 RepID=A0A515YQF6_9ACTN ---DTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFF7E9 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GYREEERFPLCSTYKALAVGFVLTRVD -QGVEKLDRRVTHGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLQSFGGP -AALTSWLRSTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLINWLVGNTTGDNRLRAGLPKEWKVGDKTGTGNNGCFADIAVVWPPDRGPILVTTFVAE -GTAPAKDIEAVFADVGKIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CY41 TaxID=2608686 RepID=UPI00135894CF ----ANASVAALEARYGAQVGLFAVDTGTGRTV-THRADERFPFLSTFKTLAAAALLRSRP -LDTGYFDRVVRFHEADLVANSPVTSAAVAEGMTLAQVAEAAITRSDNTAGNLLLREIGGP -EGLTAFLRTLGDPTSRLDRWETELNTAIPGDERDTTTPAALAADYRAAALGDALGASERD -QLVAWLKANTTGDKRIRAGLPANWVTGDKTGTGSYGCANDVAIVWPEGGAPIVIAILSRK -PDADAEANNDLLAEVTKVAVN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. P44RR-XXIV TaxID=1921145 RepID=A0A4T3FEQ1_9RHIZ ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGVEKLDRRVAYGKDKVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLESFGGP -AALTAWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLTKEWKVGDKTGTGNNGSYADVAVIWPPERGPILVTTFVAE -GTAPAKDIEAVFAEVGKIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium sp. B133/95 TaxID=1841656 RepID=UPI000810116B --eDADKQLADLEKRTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAVTLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVANTTGNARLRAGLPKEWKVGDKTGTGDNGSYADVAVIWLPDRGPILVVTYVGE -ATAPAKDIEAVFAEVGKIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI16_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGPAESWVVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00116574DA ---DTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. Rc5 TaxID=1920666 RepID=UPI00098D4EA2 ------AELTALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTIKALAAGALLAATS ---EAELDRVVRYDRAELVSHSPVTQRHVADGMTLRAVADAAVRHSDNTAANLMFTELGGP -AGLGRALRGIGDTVTNPVRTETSLNEAAPGDLRDTSTPRAMAGSLRAYALGDALSAADRG -VLVDWLRRNTTGATLIRAGVPAGWQVGDKTGAGGYGTRNDIAVLWPPEGAPIVLAVLSRR -DAKDAQPDDALIAEAARVTID-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2H0_9BACT -------AAQQVETELDARVGVAIYDTGSGTRW-QYNADEHFPMTSTFKVLACGALLARQD -VGDEDLNRQVPISQSDLVTYSPVTETQVGQEISLDALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=UPI00047C6C5D ----LTPKIRRLEAKSGGRLGVACRIAGTTAQF-GYRENELFPMCSTFKTLAAALILHRVE -GGIEQLDRSIEVPHNAVVASSPTTKNHAGGEMTVAQLCEAAVTVSDNGAANLLLDSFGGP -AQLTTYLRSIGDTVTRLDRIEPELNESAPDDPRDTTSPLAMIDDCERLALGDSLSQKSRA -QLVDWLVANKTGDDRIRAGLPKGWKCGDKTGTGDRGSTNDAAVIWPTSGNPILMSVYLTG -TKQSLAKRNAVIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix deserti TaxID=2593674 RepID=UPI00131B86B1 ----VAGEFGRLEAEFDARLGVYALDTGSGRTI-EHRADERFAYASTIKALAAGALLARTS ---PAELDRRVTYTSADLVPPSPVAEQHVNEGMTLREVLDAAVRYGDNTAANLMFTQLGGP -QELEKYLRGIGERDTEVDRVEPELNEATPGDERDTSTPRALATVLEKYVLADVLPADDRA -LLTDMLRNNTTGDELIRDGVPDGWVVGDKTGAASYGTRNDIAVLWPPDGDPIVLAVLSSR -DEKDATYDNALIAQAAKAVVT-- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. POLY-S9 TaxID=1576596 RepID=UPI000A4CE130 ------DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD -RGEESLGDLVTYKATELVPYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKDWRIADKSGAGYNGSRGIIAVLWPETGKPYLAAAYMSG -SDASFKQRNAVIAEIGKAMIE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T3S8_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTAFMRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQT -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C5QEE9_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFILGTALSIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. ROICE36 TaxID=2048670 RepID=A0A2N6ICC3_9BURK ---AAHTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAAALLARSV -SQPGLLDQHVRYEKKDLVAYSPITEKHLADGMNVADLCAAILQYSDNSAANFLMTILGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLGNSLPATERQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKNADTNQAIITAATRIVT--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Micromonospora TaxID=2617518 RepID=W7VTP0_9ACTN ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALRDVGDRVTRPVRTEPELNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD -LLLSWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR -GSRDAKPDDTLVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium sp. Ant5-2-1 TaxID=1755239 RepID=UPI00071826C4 ---AAQTQLAALEQAAGGRLGVAAWRQGSELRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLADGMSVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFARSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKVDTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus lactis 154 TaxID=743719 RepID=G4HIM8_9BACL --------FENLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLMQNS ---VEDIDEMISYSAEDLVTYSPITEKHVSTGMTLRDIMDAAIRYSDNTAGNLLLKQLGGP -DGFEAALRQIGDTVIQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPEDKQT -ILTDMLRGNTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDIAIVWPPEGDPIVLAILSSR -DAQDADYDNALIAKAAEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF04B18 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFGKILREIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE60_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNNAERMVVIYLRD -TPASMAERNQ------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. PK3_68 TaxID=2027408 RepID=A0A3A5HQN3_9BACI ---NIDEKLAQLENEFDARIGVYAIDTGTNQTI-EYRPEERFAFASTYKALAAALLLQQNS ---LEELKEVITYTKDDLVPYSPITEKHIDTGMTLLELSEAAVRFSDNTAGNLLFEALGGP -KGFEQALRQIGDNVTQADRFEPDLNTFTPENTRDTSTPKALATSLQAFVIGDLLSGEKRE -QFADLLQGNATGDKLIRAGAPEGWKVGDKSGAGSYGTRNDIAVVWPPDREPIVMAIMSRH -DTKDAKYDDALIAQAAEITL--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVW1_9BACT -----LDTARQIEARLDARVGLAIYDTGSNTSW-LYRAHERFPMASTFKVLACGALLARRD -AGHTDMEREVSIARSDLVTYSPVTERWVGRGVTLDALCAATMRTSDNTAANKVLEVLGGP -SGLTGFLREIGDDVTRVDRWETDLNEGLPGDARDTSTPAAMAASLRTLLLGDALSSASKE -TLIGWLESNRVGGALLRAGLPDDWRIGDRTGAGGHGTRGVVAIVWPRDRAPLILAVYITQ -TTASMDQRNAAIAAVGRALAQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FD47_9BACT ------------EDQLGARVVYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus muralis TaxID=264697 RepID=UPI000710BC92 -------DFAKLEKKFDAKLGVFALDTGTNETV-TYHPDERFAYTSTHKALAVGVLLQQKS ---IEDLNQRITYTREDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILKQLGGP -TGFKKALEDMGDNVTNPVRIEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSKR -DKKDAEYNDKLIAETTKEVIK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus bataviensis TaxID=220685 RepID=A0A561D039_9BACI ---HIHREFSELERKFDARLGVYAIDTGTHRIV-SYRANERFAYASTYKALAAGALLQHYS ---IDQLDQLVTYKSEDLVSYSPVTQLHVDTGMTLREVMEAAVRSSDNTAGNLLLEKLGGP -SGFEKALRKIGDNVTQVDRYETDLNTAIPGDRRDTSTPKALATNLQAFTVSDLLPSEKRT -ILTDWMRGNATGDALIRAGAPIGWEVDDKSGAGSYGTRNDIAVVWPPNRDPIVIAVLSSR -ETQNATYDNTLIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenovibrio kuenenii TaxID=63658 RepID=UPI0004666BB5 ----FSQQISELEKNYGGKLGVAVWDANTGTQL-HHRGNERFALCSTFKFLLTAAVLAKVD -SKDEKLNRVVTYSKSSLLEYAPVTRKHMQGNMTIAQLAAAAMEYSDNTAANLLFEPARGP -MGLTTFMRSIGDTVTRIDRTEPYLNTNLPNDDRDTTTPNAMLTSMKKILIGNALSPASRN -QLTQWMLNNTTGTNKLRAGIPTHWPIGDKTGSGDNGATSDIAIVWPDADNPILIAVYYTG -SKEPYEIKNHVIEQVGRIVSEQf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces ficellus TaxID=1977088 RepID=UPI0012E80E6F -----TAALEKLEREYGARLGVYAVDTGTGREV-AHRADERFAYASTFKAFAAAAVLREHS ---PGGMDEVITYAEDDLVEHSPVTEKHVRTGMTLRALCDAAVRHSDNTAANLLFDAIGGP -PGLAAALRATGDTVTRVERREPELNQWSPGAESDTTTPRAWAGDLRAFVLGDALGKDERA -QLTRWLRTNTTGDELIRAGVPKGWVVGDKTGGGGYGVRNDIAVVWRPGAAPIVMAIMSNR -GTEDAGYDNALIARAAEVVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SRB_28 TaxID=1969378 RepID=UPI000DC33D7E -----NQSFAKLEKEYDTKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKDWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011553F37 --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGIRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAT------- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudorhodoferax sp. Leaf274 TaxID=1736318 RepID=A0A0S9NQZ6_9BURK ---QAELALAALEQGFAGRIGVCALDTADGALL-GQRADERFPMCSSFKAMLAAAILARSS -TEPDLLAQQVRYGRGDLLAHSPVTTLHLDRGMSVAALCEATVQTSDNAAANLLLQRIGGP -AGLTAFMRSIGDDQFRLDRWELALNSSLPGDPRDTTTPRAMATSLRRLAVGDALAPAQRA -QLAAWLRGTTTGAERIRAGMPAGWAVGNKTGTSGYGSAIDVAVVWPPARAPLVLAVFTTR -HAADAPALDAPIAQATRIVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Arenimonas sp. 3729k TaxID=2608255 RepID=A0A5B2ZD20_9GAMM ---SLRQAWAELEARHGGRLGVAVWDTGSGLRA-SHRGDERFIMCSTFKLVLVGQVLAAVD -AGKESPERRLRWSAEDLVSWSPVTEKHVQDGLTVGELCEATLTTSDNTAANLLLAEHGGP -AGLTAWLRGIGDEVTRLDRFEPGLNVWHEGEPFDTTSLEAMLDTMHKLLLGDVLSPASRQ -RLTDWLIANQTGDNRIRAGLP-GWKVGDKTGSDGKHTSNDVAIAWPPGGAAVLVAVYYTE -SEVNAATRDSVIAEATRAF---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A379JIY1_9NOCA ------DSFASMESERAARLGVYAVDTGSGRTV-AYREGERFPMASTFKGLACGALLRDHP -LSTGFFDQVIHFSRDELVEYSPMTEQRVDTGMTVAELCEATITLSDNTAGNKVLELLGGP -AGFTAFLRSIGDEVTRLDRWETELNSAVPGDERDTTTPAALAADYRALVLGDVLGEPERA -QLKSWLVANTTGDQRIRAGVPADWTVGDKTGSPAYGGALDVAIAWPPGLAPIVIAVLTTK -SEPDAEPDNALVVDATRAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora alba TaxID=673379 RepID=A0A1I1WYS0_9ACTN -----HEDFERLEREFDARLGVYAVDTATGREL-SHRADERFAYASTHKALTAGAVLRQTS ---LEGLDKRITYDRADLVAYSPITKKHVDSGMTLRSVLDAAVRYSDNTAANLMFDELGGP -EGLGAVLREIGDTTTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFTTGDALSKDGRA -VLNRMLRNVTTGDELIRAGTPDGWRVGDKSGAADYGTRNDIAVLWPPERAPIVLAVLSDR -DAADAEYDNALIARAAEVALRSf ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=UPI000EA991FF ------REFGRLETEFDARLGVFAVDTGTGATI-GHRADERFAYASTFKALAAAVLLDRTS ---AADLDEVVRYSRSDLVAHSPVTEKHVTTGMRLRDVVDAAVRYSDNTAANLILRRLDGP -EGFQRELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYAVDDALSPEDRD -VLNGWLRRNTTGDTLIRAGVPAGWMVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR -DTRDAPYDDALIARATRIVVD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2H3NBZ4_9BACI -hqATYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---TEKLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRNSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNVLPVHKRN -IFTGWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000863DBE9 -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPEHFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Pararhizobium polonicum TaxID=1612624 RepID=A0A1C7P419_9RHIZ --nDIDKQLAALEKRTGGRLGVFVVDTASNASF-GRRQDERFAMCSTFKALAAAFVLARVD -KGAEKLDRRIPVAKTDLLSYSPVVEKQVGKGMTVRELCDAAVTYSDNAAANLLLASFGGP -SRLTAWLRAIGDEATRLDRIEPELNEAKVGDPRDTTTPAAMTRTLGKLLLEGVLSPASRD -QFAAWLVANTTGGKRLRAGLPAGWTVGEKTGTSGHGEAGDIGFMRPRAGHTILASVYIAE -GKKPIRELEPVFAAVGKLIA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A1S7D640_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMD----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00040D07EF -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRSNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLNEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGNIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVVAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. z9 TaxID=2584942 RepID=UPI001142A4C6 ----FEDALDGLERGSGGRLGVCLFDTASGRQW-GRRVDERFPMCSTFKFPLAAAVLRRVE -RGELALDRRVPIRREDLIPHAPVTEKHVGGQLSVGELCQATMIWSDNPAANLLLPLVGGP -AGVTAFLRASGDAVTRNDRDEPEVNRFSPDDPRDTTSPAAMAGSLRRLVLGEVLGAESRR -RLADWLIDNRTGDRRLRAGLPAGWKVGDKTGSNGEDTTNDIAIVWPDGRAPWLLTAYLQG -AKVDADARDGVLRQVGVAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=UPI00119D7E60 ---QLHRKFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLHQYS ---IDQLDELVTYNSEDIVSYSPVTQLHIDTGMTLREVTEAAVRYSDNTAGNLLLEKLGGP -KGFETALRKIGDNITQVDRYETELNSAVPGDARDTSTAKALATSLQAFAVSDLIPTEKRT -ILTDWMRGNATGDALIRAGAPTGWEVADKSGAGSYGTRNDIAVVWPPNRAPIVIAVLSSR -ETQNATYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus nitratireducens TaxID=2026193 RepID=UPI0008FE5A77 -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAIGALLQKTS ---IEDLDQIIKYTSKDLVNYNPITEKYVDTGMALKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE59_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGKRGARGIVALLGPNNKAERTVVIYLRD -TPASMAERNQ------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AK71_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVXLCGAVLARVD -AGDEQLERKIHYXXXXLVXYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=BLAC_PROMI ----VLEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWEPELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. BD59S TaxID=2499213 RepID=A0A516QRT3_9BACI --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFRKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKVIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEIEATYDNQLIAEAAEVVVNTf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF460E7 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPETIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces yunnanensis TaxID=156453 RepID=A0A1M7L284_9ACTN -----AAELRDLERRYAARLGVYARNARTGQVV-AHRAQERFAMCSTFKTVAAAAVLRDHA --HCAPLDKVIHYPARDILPYSPKTQEHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQLGGP -EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDLRDTTTPEAIGTSYGRLALGRVLTHDARE -QLVTWLKGNTTSEHRFRAGLPQHWVVGDKTGTGDYASANDVGVAWTGRSTPIVLAVLSTK -SAKDAPVDEALIADAARIVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013F433E4 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHSDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -AEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase 1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=BLA1_BACMY --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIASNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAPEVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA2F03 -----SQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNELHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAAATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Mesorhizobium TaxID=325217 RepID=A0A434TTM3_9RHIZ ----ATKAVEALEARNGGRLGVMILDIGTNAAI-EYRADELFPITSTFKFLAAAGVLKAVD -DGKAKLDDRIVYAASDVEPYSPVTKEHSGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP -QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK -RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNTVALLWPPNGAPILAAVYYTG -STAPRASREAVHADMARIIVETf ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus glucanolyticus TaxID=59843 RepID=A0A163IPJ8_9BACL -------DFVQLESKFSARLGVYAIDTGTERIV-AYRPDERFAYASTFKALAAGAVLQQNS ---MDTLDKVITYTSKDLVTYSPITEKNVNTGMTLRELSEAAIRYSDNTAGNLLLKELGGP -DGFRTALKQAGDNVTNPERFETDLNEAIPGDNRDTSTPRALATTLQAYTVGDELPTDKRT -LLIDWLKGNTTGDKLIRMAVPEGWEVGDKTGAGGYGTRNDIAVIWPPNKEPIVIAILSSR -DIPDATYDDALIAQAAKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI001191B733 ---AVKGDFAKLEDKFDAKLGIFALDTGTNQTV-TYHPDERFAYTSTHKALAVGALLQQKT ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDKVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLRGALPTDKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSMR -DKKDADYNDKLIAEATKEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. WSM2598 TaxID=398261 RepID=UPI00036D2175 -----VARLAALERHDGGRLGVTVRDTGTGRIL-SYRADERFPLCSTFKAVAAAAVLARVD -RGEESLDRRMAYGPGDLDAYAPETRRRVGEGIDLRAACAAAVIWSDNTAANLMLRALGGP -EAVTAFARAQGDAVTRLDRTEPSLNTAIPGDPRDTTSPAAMAALMERILVGPVLSAESRA -LLLGWMTQSPTGAERLRAGLSPGWQVADKTGTGANGTANVVALVRRPGGAPLVASVYLTQ -SPAPAEARNGLHAEVGRLVARTf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE57_KLEPN ------DQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQ------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1C4AMF4_BACCE -----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2C0WW61_BACCE ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLINYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDIVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BA2 TaxID=436595 RepID=UPI001329A657 ------GDLKALEDKFDARLGVYAIDTGTGREV-AYNAGERFAYNSTFKALAAGAVLGKYS ---LSGLDRKITYSKDDLVANSPVTEKHVDTGMTLGELCDAAVRYSDNAAANLLFDQLGGP -KGLDAALERMGDDVTRMERREPELSTWVPGETRDTSTPRALAKDLRAFVLGDALRKGERA -QLTKWLKTNTTGDKTIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPSDGDPIVMAILSNR -GKKDAEPSDKLIAEATSVAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0J7EMG5_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0005C64CCB ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -AEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1C3T490_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. UMB0899 TaxID=2029108 RepID=A0A2N6R707_9BACI ----SEHDFSKLEDTFDANLGVYALDTETGHTI-SYHSEERFAFASTSKALAVGVLLQQKS ---IEDLEERITYTREDLVTYSPITEKHVDNGMTLRELSDASLRYSDNTAANLIFKQLGGP -VGFKQALRQLGDDVTNPERIEPDLNDVNPGETHDTSTAKALASSLRTLALEDVLKREKRE -LLLDWMKRNTTGDALIRAGVPEGWEVADKTGAASYGTRNDIAIIWPPNEEPIVLAILSSR -DEKEAAYDDKLIAEATKVVISAf ->[subseq from] Beta-lactamase n=3 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI000219FD72 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFCPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1S9XX24_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas monteilii TaxID=76759 RepID=A0A120HJY5_9PSED -----RQRLATLERTHGRTLGLWALETGSGQRL-AYRADQRFAFCSAFKVLLAGAILQRNE -AEPGLLAQHIDYDAATLVTYSPITQDHLETGMRVADLCAAALQYSDNTAANLLLAQVGGP -AGLTAFARRLGDAVFRLDRDEPTLNTALPDDPRDTTTPLAMGMTLERLLVGKALTVPSRH -QLQAWLEGNTTGASRIRAGVPGDWRVGDKTGTGDYGVANDVAIVWPPGRAPWIVVLFTRG -PDPSSPGDSALIAAAMREVAGAw ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=A0A1C6U248_9ACTN ------RHFSELERQFGARLGVYAIDTGTGRTV-THRADERFAHASTFKALLAGVLLRRLS ---DADLRRVIRYTEADLLEWAPITSKHVATGMSIEDLIAANVQYSDNTAANLLLEEIGGP -KGLQRELRKIGDRTTNTNRNEPTLNEATPGDPRDTSTPRALATDLRAFALGDVLPAPRRQ -KLIDLLIGNTTGDPYIRAGIPAGWQVGDKTGSGGYGTRNDIAVVWPPTGAPLIIAVLSDR -GVPDAPSADTLIAEATEAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus profundus TaxID=372463 RepID=A0A417YFW8_9BACI --qTTDNDFAQLEKEFDAKLGVYALDTGSGKII-DYQADERFAYTSTFKPLAAGAVLKQNS ---FEELNETVTYTEDDLVTYSPITEKHVDTGMNLLEISEAAIRYSDNTAGNLLFNELGGP -DGLEKAMREIGDNVINSDRTETNLNEAKPGDVRDTSTPKALATSLQAFALDQLLSESKQD -MLLEWLKTNTTGDTLIRAGVPEDWTVGDKSGAGGYGTRNDIGIVWPPDREPIVIAILSNR -DTEDAEYNDDLIKQATEITVD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A420H426_9BACI --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLISEATEVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2C1D4C5_BACCE -----NQSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSGERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRKIGDTVTNPERFEPELNEVQPGENHDTSTPKALATSLRTYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Stappia sp. ARW1T TaxID=2135615 RepID=A0A419Z8P4_9RHOB ---DIEGRLAALENKQGGRLGIAIHDVASGQTF-GNRLNERFLMASTFKLMLAAFVLARVD -REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTLSDNTAANLLLASFGGP -AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPAAMAETLRKLLFGDALSRRSRD -RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSGRGALIVTAYCEM -PKAEAKTRDATMAEIARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. UMB0893 TaxID=2066053 RepID=A0A2N5FGS7_9BACI ----VEAGFKNLEKEYEARLGVYALDTGTNKSV-SYRADERFIYASTHKALAVGALLQKKS ---IEDLDERITYTEEDLVNYNPITEKHLDKGMTLKELSDASIRYSDNTAGNLIFEAIGGP -AGFKESLRGIGDKVTEPERIEPDLNNVKPGETRDTSTPKALAESLQAFTLGDALPAEKQN -LLIDWLKRNTTGDALIRAGVPEGWIVGDKTGAGSYGTRNDIAVIWPPKGSPIILAVLSSR -DEADAEYDDELIAKATEEALK-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL27I4N3 TaxID=1938805 RepID=A0A3D9MSH7_9BURK ---AVRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD -RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP -TGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDVAILWPPGRGPVLVTVYLTE -TDGKAARSNAAIADVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E0F484A ---ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRQ -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Rummeliibacillus sp. TYF-LIM-RU47 TaxID=2608406 RepID=UPI00123AFABC ---HTEEAFKQLESEFDARLGVYAIDTKTKKSV-SYQSDERFAFASTYKALAAGAMLKQKS ---MKDLDKIITYTKDDLVTYSPITEKYVDKGMTVKDIATAAIRYSDNTAGNLLFNELGGP -TGFEKALRMMGDKVTQSNRLEPELNLTTPGDLRDTSTPRALASNLQKFVIGDVLPTKKKA -LLTDLLVGNATGDTLIRAGVPKDWVVADKSGAGGYGTRNDIAVVWPPDRKPIVIAILSSR -NTKDATYDDALIAKAAKVVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Kineococcus radiotolerans (strain ATCC BAA-149 / DSM 14245 / SRS30216) TaxID=266940 RepID=A6W9C8_KINRD ---DVAAQLARLEREFDARLGVFALDTGTGASV-VHRADERFAYASTFKVLAAAAVLDRTS ---AEELDEVVPFTAEDLVDHSPVTELHVGAGMSLRDLAAAATTVSDNTAANLLLEHLGGP -GGFESALRELGDTVTDPERTETALNEAAPGDVRDTSTPRAMATDLHAYALGDALGEEDRA -VLVGWMRANTTGDALIRAGVPEGWVVGDRTGAGGYGTRNAVAVVWPPAGAPLVLVVMSDR -DAEDADHDDALVAAATAVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00051588BB -------DFKKLERAFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALSAPERA -QLTTWLRTNTTGDAVIRAGVPENWTVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAKPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF7F4A5 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SKFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus oceanisediminis 2691 TaxID=1196031 RepID=A0A160M853_9BACI ---NTKQKFKKLEKEFDARLGVYAYDTGTKKTI-TYRSNERFAYASTFKPLAAAILLQRKS ---LEEMNEIITYTSDDLVTYSPVTEKHVKTGMTLRELCEAAIRFSDNTAGNLILEELGGP -EGFEAALKEMGDTVTKPERFETDLNEAEPGDIRDTSTPEALAASLQKVLIGHFLTEEKRN -ILTEWMRGNVTGDPLIRAGVPSGWEVADKSGAAGFGTRNDIAIVWPPNREPIIMTILSSR -DSKDAEYDNALIAEAAEMAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. jys28 TaxID=2571125 RepID=A0A4U0NJ48_9ACTN ------PQFAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAAAAVLHRNP ---LGHLDKRVTYTEADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -TRLTAYLRGLGDSVSRMDHYEPELNRVRPQDPRDTTTPRAIAADYRKLVLGDALSTDKRA -LLKDWLERNITGAKRIRAGLPKGWTVADKTGTGDYGRANDIAVAWPPHGTPLVLAIMSDR -PGYHTPPKDSLIAETAKQII--- ->[subseq from] Beta-lactamase n=1 Tax=Psychrobacter sp. TaxID=56811 RepID=A0A3D3KIC2_9GAMM ----ILEAVTNAETELGARIGLAVHDLETGKRW-EYKSNERFPLSSTFKTLACANVLQRVD -LGKERMDRVVRFSESNLVTYSPVTEKHVGKKMSLAALCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVMTLEKLLVGETLSIKSRQ -QLVSWLKGNEVGDALFRKGVPNDWIVADRTGAGGYGTRAITAVMWPPNRKSIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia abscessus TaxID=120957 RepID=UPI0002E8B2CB ---AANASLAEVEARYGAQVGLFAVDTGTGATV-THRADERFPFLSTFKTLAAAALLHAHP -LDTGYFDRVIRFHEADLVEHSPVTGAAVADGMTLAQVAEAAITRSDNTAGNLLLRELGGP -EALTAFLRTLGDPTSRLDRWETELNTAIPGDERDTTTPAALAADYSALVLGDALGARERD -QLITWLRANTTGAERIRAGLPAGWVTGDKTGTGSYGCANDVAVVWPEGGAPIVIAIQSRK -ADVDAEVNNALLAEVTKAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9YEZ6_9ACTN ------REFGRLETEFDARLGVFAVDTGTGATI-GHRADERFAYASTFKALAAAVLLDRTS ---AADLDEVVRYSRSDLVAHSPVTEKHVTTGMRLRDVVDAAVRYSDNTAANLILRRLDGP -EGFQRELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYAVDDALSPEDRD -VLNGWLRRNTTGDALIRAGVPAGWMVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR -DTRDAPYDDALIARATRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5IR39_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1N6TGW1_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-SYRHNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVDYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVADKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLISEATEVIVK-- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A2C2GFR1_BACTU --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGH -KGYEKALRKMGDWVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A2T5NXB3_9NEIS -----ARQLAELERNAGGRIGVFAQEVDSGRSL-AYRADERFPMCSTFKLLLVGALLQRSA -AQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP -QEVNRFARSLGDGLTRLDRIEPELNRAEPGDPRDTTTPAAMTANLHALLFSPLLPERQRG -LLNDWLLGSTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG -SSAMMDERNAVIAAVARVAAAEf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia lijiangensis TaxID=299618 RepID=UPI0009FCBED1 ------DRFVALERQYGARLGVFAVNTATGESV-AYRPDERFAMTSTFKGLACAALLHRHP -LATGYFDQIVRYGREELVEYSPVTETRVDSGMTASELCDAAITVSDNTAGNQILKLLGGP -PGLTAFLRSIGDPVSRLDRWETELNTAIPGDERDTTAPERLAANYRAAVLGDVLGEPERA -RLTQWLIANTTGDTRIRAGLPAGWRVGDKTGLGSYGTNNDVAIAWTEAGAPIAIAVMTTK -PDQDAKADNALLADATRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia puris TaxID=208602 RepID=A0A366DJ93_9NOCA ------PEFADLEARHDARLGVFAVDTGSGRSV-AHRADERFPMASTFKGLACGTLLVRHP -LATGYFDQVVRFSADELVEYSPVTETRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP -EGFTASLRALGDDTSRLDRWETELNTAIPGDERDTTTPAALVAGYRALVVDDALAEPERA -QLTAWLVANTTGDTRIRAGVPDDWKVGDKTGTPAYGSALDVAVAWPPGRAPIVIAVLSTK -SEQDAEADSALLAEATRAAVH-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Ji-3-8 TaxID=2708539 RepID=UPI0013EE0B8D -----SRSIVALEARSGGRLGVSVLDTANGKTF-AYRGDERFAMCSTFKALVAGLVLKRVD -QGLERLDRRIVYGKNVLLAHSPATEKHVGEGMTVGALCEATVTLSDNAAANVLLYTFGGP -PALTAFLRGLGDKVTRLDGYEPELNVVRPGEIHDTTSPNAMLATLRTLTLGSVLSPASRQ -QLVAWLVGNQTGDRRLRAGLPPGWKVGDKTGSWGDGTTNDIAVIWPPGRSPLLITAYLSR -STLDDDGRNAAIAEVARLVT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS057 TaxID=1982764 RepID=A0A209DAA0_9ACTN -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAGPERA -RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVR5_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEMLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=A0A0P6WTD1_9BACI ----TVNKFMQLEKKFDARLGIYAIDTGTNRTV-VYRPDERFAYTSTYKALAAGAVLQQNS ---IGELDEVITYTKDDLVTYSPITEQHVDTGMTLKEIGDAAIRYSDNTAGNLLLQELGGP -NGFENALRQNGDHVTEADRYETDLNSAIPGDIRDTSTARALATSLKAFTVDGILPNGKRT -LLTDWMRGNTTGDELIRAAAPKGWEVGDKSGAGDYGTRNDIAIIWPPNRDPIIIAILSSR -DTKDATYNNELIAKAAKVALSSf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock4-18 TaxID=526988 RepID=A0A2I0R834_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTGTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Herbihabitans rhizosphaerae TaxID=1872711 RepID=A0A4Q7L6P5_9PSEU -----HDRLAELEQRFGARVGVFAVATGTGNTV-AHRADERFAFCSTFKALATAAVLHRDP ---MSHLETVVRYTPADLMKSSQITRQHVSTGMTIRQVCDAAVRYSDGTAGNLLFRELGGP -ARLTEFLRSIGDTVTRMDRIEPALTEATPGDPRDTSTPRALGTSYQRLVLGDTLPPDKRA -FLRDLMERNTTGAQRIRAGVPQGWVVADKTGTGDYGTVNDIALVWPPNTPPLLIAIMSSK -PARDATYDQALIAEAARYAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1813 TaxID=1463888 RepID=UPI0004C55A95 ---RAAKALAQVERRFHARLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAGVVLKRST ---DDELNRVIHYSASDLEEYAPITKRHVGKGMTLRDLVKAALQYSDNTAANLLLDQLGGP -AGLQKALRERGDTTTRVDRTEPTLNEAKPGDTRDTSTPRALGTDLRGFVLGDVLPEGRRQ -LLTSWLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPTSGAPIVVAVLSDR -GSKDAASDDALIKDATKA----- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus halosaccharovorans TaxID=930124 RepID=UPI000994EAE4 ----SQDEFSKLEEKYDAKLGVYALDTGTDVAI-SYRPDERFAYASTSKALAVGVLLQQKS ---IEDLNETITYSRDDLVTYSPITEQHVDTGMTLRDLSDASLRYSDNTAANLIFEQIGGP -EEFKHALRQIGDDMTNPERMEPELNDVAPGETHDTSTAKALAASLQTFALEDALPPEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAASYGTRNDIAIIWPPNEDPIVLAILSNR -NEKDATYDDELIAEATKVVLSAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NTK 937 TaxID=1487711 RepID=A0A069K245_9ACTN ---DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP -KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDNWTVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR -DGEDDAYDNRLLAKAAAVVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFD5B78 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGSLLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces peucetius subsp. caesius ATCC 27952 TaxID=316280 RepID=A0A2D3UGV6_STRC0 ----FAHELRALEGKYDARLGVYAVDTGSGREV-AYNDGERFAYASTFKALAAGAVLRKYS ---TNGMDRVVTYSADDLIAHSPVTAKHVGTGMSLRDLCEAAVRYSDNTAANLLFDALGGP -GGLDAVLEAMGDDVTRMERREPELSRWAPGETRDTTTPRAFAKDLRAFVLGDALGRNERA -QLTKWLRTNTTGNELVRAGVPKGWVVGDKTGTGGYGARNDIAVVWPPDSAPIVMAIMSNR -GDKDADHDNKLIAEAAGVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas hortorum pv. carotae str. M081 TaxID=863365 RepID=V7Z9E4_9XANT ----LRARWAEIERGTGDRLGIGLLDSATGKHF-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -QGLTAFLRGIGDAQTRSDRHEPEMNRFAQDDPRDTTTPAAMALTLRTLLLGDALQPTSRK -QLTDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -ASVDSDARDAALKAVAQAVASY- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis serovar argentinensis TaxID=180880 RepID=A0A243KNY1_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-TYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFGKILREIGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F5426 ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRIEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01883 TaxID=1703943 RepID=A0A1Q5KS96_9ACTN -----EAELRDLEQRYDARLGVLARNVRTGRTL-SHRAGERFAMCSTFKAFAAAAVLRDHG --DRAPLDRVIPYPPHDILPHSPRTQENLATGMTVGDLCAAAVQYSDNAAGNLLLREIGGP -AGLTRFLRSLGDDVSRLDRWEPELNTAIPGDLRDTTTPRAIGAGLERLALGRALGDADRE -RLVGWLKGNTTGAERFRRGLPDGWVLADKTGTGSYATANDIGVAWTTGRTPVVLAVLSAR -STEDATVDEALVAEAARVIAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=UPI000B84D51B ------RHFSELERQFGARLGVYAIDTGTGRTV-THRADERFAHASTFKALLAGVLLRRLS ---DADLRRVIRYTEADLLEWAPITSKHVATGMSIEDLIAANVQYSDNTAANLLLEEIGGP -KGLQRELRKIGDRTTNTNRNEPTLNEATPGDPRDTSTPRALATDLRAFALGDVLPAPRRQ -KLIDLLIGNTTGDPYIRAGIPAGWQVGDKTGSGGYGTRNDIAVVWPPTGAPLIIAVLSDR -GVPDAPSADTLIAEATEAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE38C95 ---DADVRLAALEKATGGRLGVSVLDVAMNISF-GRRQEERFAMCSTFKMLAAACILARVD -NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP -EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPHAMLTTMGKLLLDDALSDTSRD -QLTAWLVGNKTGDKRLRAGLPKAWKVGDKTGTSATGAIGDVAIVWPSPNRPILVTAYIAE -ATKPAKELEYIFAEIGKMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3626 TaxID=1463926 RepID=UPI0004C04656 --------LTDLEREYGARIGVYAVATGTGATV-IHRADERLALCSTFKTLAAAAVLDRGP ---LTRLDRRVTYTRADLVPYSPVTGRHVDTGMTLRELCDAAVRHSDNTAANLLLRDIGGP -SALTAHLRGLGDRISRLDHTEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPAAKRA -LLTDWLVGSTTGGKRIRAAVPGDWKVGDKTGTGDWGRAHDIAVLWPPRGAPLVIAVLTEH -PDRDAAADDALVAEAARRT---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK387 TaxID=2512128 RepID=A0A4R2EAK2_9ACTN ---AAHAELAELEQRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDLLPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFHRSLGDEVSRLDRWEPELNTAIPEDPRDTTTPQAIAASLERVTLGRALARADRE -RFIGWLKGNTTSSARFRKGLPKEWVVADKTGTGDYATANDIGVAWTTRRTPLVLAVLSGK -GTPDAPVDEALIADAAAVVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FA74_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTSKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVAEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI000F89CD9F ---SVRDALAALERTSGGRLGVCAIPTCKPREI-RYRADERFPFCSTFKVVLAAAILARSL -DVPDLMRRRIRYTKHDLAHYSPVSSKHVEDGMTVAELCQAAIQYSDNTAANQLMKVLGGP -QAVTAYAHATGNAAFRLDRWETELNTAIPGDLRDTSTPAAMARTLQTLTVGQALPSAQRD -QLVTWLRGNTTGAHRIRAGVPADWQVGDKTGTGDYGTANDLAILWPPGRAPIMLAVYFTQ -REPKAKARDDVIAAAARIVA--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD0490 --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKGDLVEYSPVTERHVDTGMTLGKIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMEDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPNGWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIEEAAKVVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. G3(2015) TaxID=1706731 RepID=UPI0007385AF6 ----SHDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKKDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillaceae TaxID=186817 RepID=UPI00041B53C0 ---DIKATFSKLEKEFDARLGVFALDTGTNKTI-AYRSEERFAYASTHKALAVGALLQQKS ---MEDLEQRITYTKDDLVNYNPITEKHVDTGMTLKELSDASIRFSDNTAANLIFNQIGGP -SGLKDTLRGLGDEVTNPQRKEPALNEFTPGETADTSTPKALVTSLQAFTLGDVLPEEKRT -ILVDWLKRNTTGDNLIRAGVPSNWEVADKTGAASYGTRNDIAIIWPTKGDPIVLAILSDR -DKEDADYNDKLIAQATKKVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia megapolitana TaxID=420953 RepID=A0A1I3RC63_9BURK ----AETLLAELERSSGGRLGVSALNTASGERI-GYRAEERFPFCSTFKLILSAAILARST -QDSGLMQRRIRYAASDLVSSSPLTTKHLAEGMTVGELCAATLQISDNTAANLLIKVLGGP -AEVTAYARSIGNESFHLDRTETTLNTAIPGDTRDTATPASMALSLQTLVLGESLPQAQRT -QLTAWLRANRLGDQRIRAGVPADWQVADKTGTGEHGTANDIGVLWRPTGAPIVLALYYTQ -GSEDEKVHSGVLAAAARIVASAf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. 8-3EHSu TaxID=2510978 RepID=A0A4Q7J1I7_9PSEU ------AEFGQLESRFAARLGVYAIDTGSGREV-AFRPDERFAFASTFKALAAAAVLRANT ---PAELDQIVRYTRADLQEHAPIAEKHVDTGMSLRALCDAAVRYSDNTAGNLLLNELGGP -AGLTRVLRELGDQTTRSDRMEPELNEATPGDPRDTSTPRALAGSLRTFALGDALAADKRE -IFVDLLRRNTTGDKVIRAGTPAGWVVGDKTGTADYGGRNDIAVIWPPGRAPIVLALLSAR -SSTEDQPQDALLAEATKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFA8056 -----NQSFAKLEKEYDAKLGIYALNTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. b62 TaxID=1827627 RepID=UPI000BF19A3D -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALHPPERA -QLMTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI0009EB1575 ----TVNKFMQLEKKFDARLGIYAIDTGTNRTV-VYRPDERFAYTSTYKALAAGAVLQQNS ---IGELDEVITYTKDDLVTYSPITEQHVDTGMTLKEIGDAAIRYSDNTAGNLLLQELGGP -NGFENALRQNGDHVTEADRYETDLNSAIPGDIRDTSTARALATSLKAFTVDGILPNGKRT -LLTDWMRGNTTGDELIRAAAPKGWEVGDKSGAGDYGTRNDIAIIWPPNRDPIIIAILSSR -DTKDATYNNELIAKAAKVALSSf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BEF7932 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLCKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Ornithinibacillus sp. TaxID=1898027 RepID=A0A3C1I5A7_9BACI --eSIDEKFAELENEFNARIGVYAIDTGTNQTI-EYRPEERFAFASTYKALAAAILLQQNS ---LEELEEVISFTEDDLVPYSPITEKHVDTGMTLLELSEAAVRSSDNTAGNLLYEGLGGP -KGFEQALRQIGDNITHADRFEPDLNAFTPGDNRDTSTPKAFATNLQAFTLGDVLSDEKRE -LFIDWLKGNATGDTLIRAGSPEEWVVGDKSGAGSYGTRNDIAIVWPPNREPIVIVIMSNH -DTENAEYDDKLIAQAAKVTL--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI0011A5B19D --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDIGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF3AB72 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFTFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI00124B9717 -----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD -VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DRKDATPDDAVIAQATRVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI00103424CF ---MLRAQWAQIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI001034B2ED ---MLRAQWAQIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEAFPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CB61E2 -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALHPPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B4BJ63_BACTU -----NQSFAKLEKEYDAKLGIYAFDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKHLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Azorhizobium doebereinerae TaxID=281091 RepID=UPI0004194CC9 ---ALADGIAALEAGSGGRLGVSVRDTGTGAGF-AHRGAERFPMCSTFKFLLAAAVLSRVD -QGRMDLSRVIPVTPADLVDYAPVVEKKVGQGLSVAALCDAAVTLSDNGAANLLLREIGGP -QAVTEFARALGDPVTRLDRNEPALNVVPPGETLDTTTPDAMLADLDALVLGHALSPGARQ -MLTGWLVGCRTGDKRLRAGLPQGWKVGDKTGTGPTGSANDVAVAWPPGRAPLLITSYLTA -SRLDGPGNDALHAAVARLVAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus bataviensis TaxID=220685 RepID=K6CKQ2_9BACI ---HIHREFAELESKFDARLGVYAIDTGTNQTV-SYRPNERFAYASTYKALAAGALLQHYS ---IDQLEELVTYNSEDIVSYSPVTELHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -EGFETALKQIGDKVTEVNRYEPDLNSAIPGDKRDTSTPKSLATSLQAFAVSDLLPTEKRK -ILTDWMRGNATGDALIRAGAPTGWEVADKSGAGSYGTRNDIAIVRPSNRAPIIIAVLSSR -DTQNATYDNTLIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000CD7EAAD -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEAFDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SAFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. 7884-2 TaxID=2022552 RepID=UPI000BA56C55 --qTTDNDFAQLEKEFDAKLGVYALDTGSGKII-DYQADERFAYTSTFKPLAAGAVLKQNS ---FEELNETVTYTEDDLVTYSPITEKHVDTGMNLLEISEAAIRYSDNTAGNLLFNELGGP -DGLEKAMREIGDNVINSDRTETNLNEAKPGDVRDTSTPKALATSLQAFALDQLLSESKQD -MLLEWLKTNTTGDSLIRAGVPEDWTVGDKSGAGGYGTRNDIGIVWPPDREPIVIAILSNR -DTEDAEYNDDLIKQATEITVD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas bromi TaxID=56449 RepID=A0A1C3NJJ9_9XANT ----LRAQWADIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD -EGKLTLAQPVKIRASDMLEHAPVTERHVGGALSVGELCRATMIYSDNPAANRLFPLVGGP -PGVTTFLRSIGDAQTRSDRHEPEMNRFAPDDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDLAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Jiangella gansuensis TaxID=281473 RepID=UPI00047897AC ------DAVSALEQAYDTTIGLAARNLDTGARL-IHRAADRFPMLSVFKTLAVAAVLRDHD -EHGETLRRRVWYPPADVLEYAPVAAEHVDTGMTVAELCDATLRLSDNTAANLLLREIGGP -RGLTAFIRSIGDHVTRLDRWEPDLNTAVPGDERDTTTPAAIARAYAGLLTGTTLSRPDRN -RLTSWMLDNQTSDTRFRAGLPRGWRLADKTGSGAYGTNNDVGVAWSPDGTPVVIAALSRR -DRPDATGNDEVLAELARLVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000D51D327 -----DREFAKLEEKYDAHLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQKYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYGTRNDIAILWPPKGDPIVLAILSDR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. LTSP857 TaxID=1619231 RepID=UPI0005D2B547 -------ELESYERESGGRIGVYAENLATGAKL-IWRADERFVMCSTFKASLAACVLARVD -RGEEQLAATIPYGQADLLDYAPIAKQNLATGMSVAEMCKAIIELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGDPHDTTTPAAMANNLRRLVTGEALSQASRT -QLTDWMVNCKTGANRLRGGLPADWKIGDKTGNNGKDASGDIAIVWPKPDRPILIAAYTQG -GTPTAAQIEAVFARIGRMVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora orduensis TaxID=1420891 RepID=A0A5C4QNS5_9ACTN ------REFRLLQERFDARLGIYAIDTGTGRTV-RYRADERFGYCSTFKALAAAEVLDGTT ---DAELDRVVRYSADDLVTYSPITERHVADGMTLRAIADAAVRYSDNTAGNLLLRQLGGP -QRFEKELRGVGDSVTDPARYETELNEARPGDRRDTSTARALAQDLRAYVVGDALEPADRD -VLTGWLRGNTTGGELIRAGVPDGWVVGDKTGAGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDASYDNALIAQAAEVVIA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDKVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=O33677_SERMA ---ETLVKVKDAEDQLGSTSGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGS -QELTAFLHNMGDHVTRLDRWEPELNEAIPNDEADTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMADKVA-GPLLRSALPAGWFIADKSGARERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SM18 TaxID=1736046 RepID=A0A2S2GGQ5_9ACTN ---ETAEAFEKLEGEFDARLGVYAVDTGTGREV-THRADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSENDLVPNSPVTEKHVGTGMTLDALCDAAVRHSDNTAANLLLDRLGGP -KGLGALLAELGDDVTRMERREPELSSWVPGSTRDTTTPRAFAGNLRAFVLGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDDWTVGDKTGTGGYGIRNDIAVLWPPGRAPVVVAVLSNR -DGEDDAYDNRLLAKAAAVVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF27D1C -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---MEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus luti TaxID=2026191 RepID=UPI0012E743A7 --qATHKEFSQLEKKYDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNA ---MDKLNEVIKFTKEDLVEYSPVTKRHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEEALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNREPIIIAILSSK -DEKEATYDNQLIEEAAEVVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Aureimonas sp. N4 TaxID=1638165 RepID=UPI000785A3D7 ---DLDALWAEIENRFSARLGAFVWDMETDRRW-ARRADERFPLCSTFKLVAAAGLLARVD -AGEENLSRRVVIAKSDLVTYSPETEKHVGGEMTLSSIAEAALTQSDNTAGNVLIDLLGGP -EGVTRTARGFGDETFRLDRRETALNEAKPGDPRDTTSPAAMTKMLHALLFGEVQKPDSRR -QLADWMVANRTGDAKLRAGLRKDWRVGDKTGGGDFGTMNDVAVIWPPAGKPILISLYLTE -TKASFDERNAAFAEVGRAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas perforans TaxID=442694 RepID=UPI00115DAE2D ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLRRGD -QGKLTLAQQVRIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGEP -AGVTAFLRGIGDAQTRTDRYEPQMNRFADDDPRDTTTPAAMAATLRTLLLGDALHPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00101CF080 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEVLENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus sp. H1a TaxID=1397276 RepID=UPI0009E018E4 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---INKLNEVITYTKEDLVEYSPITEKNVGTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP -KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKEFTVGNALPADKRK -ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DEKEATYNNELIAQAAEVVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus khoisanae TaxID=880157 RepID=A0A0J5FV31_9GAMM ---QLIHQLSILEKNANGRLGVVLIDTSDHSTF-AYRANERFPLCSTSKFMAVSALLKKNE -ANDHLLNQRIHYQQSDLVEYSPITEKHLKNGMTLRELGEATMQYSDNAAMNLILNQLGGP -NEVTQFARTIGDNDFRLDRKEPDLNTAIPGDERDTSTPQAMANSLYHLALGNTLETAQRE -QLVAWLKGNTTGGASIRAGVPENWVIGDKTGRCSYGTINDIAVIWPTNRSPLVLVTYFTQ -PNQNANARPDVLAEAARIVTQ-- ->[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A1U7AE39_9BACT ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=2 Tax=Pseudovibrio sp. Ad26 TaxID=989410 RepID=A0A165TV92_9RHOB ---ELMDTVTRLESEVGGRIGVVLQHTGSEWGI-EHREDERFPMASTFKALLCGAVLSRVD -RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNTAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPALNEAKHGDSRDTTTPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPETGKPYLASVYMMG -SDASFKQRNAVIADIGKAMIE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=J9BF03_BACCE -----NQSFVKLEKDYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALAISLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKKDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase protein n=1 Tax=Agrobacterium radiobacter (strain K84 / ATCC BAA-868) TaxID=311403 RepID=B9JBH3_AGRRK --eDADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAVTLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVANTTGNARLRAGLPKEWKVGDKTGTGENGSYADVAVIWLPDRGPILVVTYVGE -ATAPAKDIEAVFAEVGKIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Massilibacterium senegalense TaxID=1632858 RepID=UPI000AEC23DB ---NTDEKFTQLENEFDARIGVYAIDTGSNQTI-EYRSEERFAFASTYKALAAAILLQQNS ---LEELKEVITYTEEDLVTYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLLEALGGP -KGFEQALREIGDNVTKADRFEPDLNYFTPGDTRDTSTPRALATSLQAFAVSDLLSNDKHE -LFTDWLKGNATGDTLIRAGAPEGWEVGDKSGAGGYGTRNDVAIVWPPNREPIVIVILSRH -NTEDAEYDDTLISQAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Modestobacter sp. KNN46-3 TaxID=2711218 RepID=UPI0013E0DCEC ----VGEALTALEGEFDARLGLYAVDTGSGQVV-AHRADERFGYASTHKALSAAAVLDRTS ---DAELDQVVTYTAEDLVPHSPVTEAHVGAGLPLRELAAAAVQHSDNTAANLLFDRLGGP -AGLEQALRDLGDDVTSVDRTETALNTAVPGDVRDTSTPRALATDLQAVLLGDALDPADRD -LLTGWMRDNATGGTLVRAGVPADWQVADKSGGGGHGTRNDIAVVWPPDGAPIVLAVLSSR -DEADAEYSDALIARATDIAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BPSDS2 TaxID=2571021 RepID=UPI0010C16F54 ------EGFRKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGLDKRVTYTRENLVANSPVTEKHVDTGMTLEELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDRQEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF7CB29 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Prauserella sp. YIM 121212 TaxID=1477506 RepID=A0A318LRD1_9PSEU ----AHREFGELEQRFDARLGVYAIDTGTGREI-AHRAGERFAYCSTFKALATAALLSERT ---VAELDVVVPYTEADLVTYSPVTEKHAGAGLPLREVMDAAVRYSDNTAGNLLLRELGGP -KGLQAALREVGDETTHVDRYEPELNEATPGDIRDTSTPRAMAGTLRAYALADALTAEKRA -IFVDMLRRNLTGDELIRAGVPDGWVVGDKTGNGDYATRNDIAVVWPPDRAPIVLALMSSR -SEKEAEHDNALLAEATKTVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=C2PWT7_BACMY -----NQSFVKLEKDYDAKLGIYALDTGTNQIV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYGLGDILSVEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIILAILSNH -AKEDTKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Tue 6075 TaxID=1661694 RepID=A0A1L6PTS1_9ACTN -------HFKELERKFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAQDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces glebosus TaxID=249580 RepID=A0A640SU30_9ACTN ----SAQAFKDLERKFDARLGVYAINTGTGREV-SYHQDERFAHASTFKALAAGAVLQKYS ---LPGMDKVITYSRDDLVPNSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP -KGLDAVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA -QLAKWLQTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR -TQKDAKYDDALIARAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000851D5E4 -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS ---LDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDELIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A150C8D9_BACCE ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGSLLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKTLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSFGTRNDIAIIWPPNKKPIMLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. NXC24 TaxID=2048897 RepID=A0A2L0W895_9RHIZ ---DADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLTNWLANNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTYVGE -ATAPAKDIEAVFAEVGKIIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Rc2d TaxID=1855321 RepID=A0A1G8UE41_9BRAD -------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGDALSPASRA -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG -GTPSAAQIAAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B9AWU0_BACCE -----NQSFVKLEKEYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKKNTTGDNLIRAGFPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. S3 TaxID=486398 RepID=A0A513RN08_9BACI ---QLHRKFAELENKYDARLGVYAIDTGTNRKV-SYRPQERFAYASTYKALAAGALLQHYS ---MDQLDELVTYNSEDIVSYSPVTQLHVDTGMTLWEVAEAAVRYSDNTAGNLLLEKLGGP -EGFETALRQIGDHVTQADRYETDLNSAVPGDKRDTSTPKALATSLQALAVSDLLPTEKRT -ILIDWMRGNATGDTLIRAGAPTGWEVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTQNATFDNTLIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Hyphomicrobium sp. NDB2Meth4 TaxID=1892846 RepID=UPI00093141CA ---DIDATLAEIEAGIKGKLGVAIIDTKTGELY-ARNQFERFPLCSTFKLLAVALVLVRVD -NGEEKLDRHIVIAKDEIVPYSPVTEKQVGGEMTIAALCEAAISRSDNTAANVLLKTLGGP -EALTNWLRTLGDKATRLDRAEPALNDVPEGDFRDGTTPRAMAYTVQRILLGNVLSKTNEK -QLLDWLIANKTGDARLRAGLPSDWRVGDKTGTCK-GTTSDVAIVWPPNHPPLIIAAYLTA -PGASPEAREKALAAVARAAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Stappia indica TaxID=538381 RepID=UPI0009F49B9E ---DIEGRLAALERKQGGRLGIAIHDVASGQTF-GNRLNERFLMASTFKLMLAAFVLARVD -REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTMSDNTAANLLLASFGGP -AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPGAMAETLRKLLFGDALSRRSRD -RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSSRGALIVTAYCEM -PKAEAKTRDATMAEIARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus sp. SCU50 TaxID=2663022 RepID=A0A5Q2TQ15_9BACI ----IDEEFAQLEGEFDARLGVYAIDTGKNQIV-EYNPDERFAYASTFKVLAAATLLKQNE ---IKDLEKVVTYSKEDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -NKLEQALRDIGDDVTEPERYETELNEFTPGSESDTSTPRAMATNLKKVALDDFLPNEKRE -LLIDWMKGNATGDALIRAGQPEEWVVGDKSGAASYGTRNDIGIVWPPNREPIVIAVMSRH -DTQDAEYDDELVAKAAEIT---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella enterica subsp. enterica serovar Altona TaxID=1151173 RepID=A0A140GPJ5_SALET ---ETLVKVKDAEDQWGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCAAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQ--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora halotolerans TaxID=1981512 RepID=UPI0013D2064B ----TDALFAALENEFDARLGVYAVDTGSEITV-TYRSDERFAYASTHKALSAAVLLDQNS ---LADLDEVITYDADDLVAHSPVTEQHVRTGMTLRELCDAALRFSDNTAANLLLAEIGGP -DGLDRALAEIGDDTTSVDRWETALNEATRGDIRDTSTPRALATDLRAFALGDALPAEKQE -LLIDWMRRNTTGDTLIRAGVPDGWEVGDRSGGGGYGTRNDIAVIWPPGDDPIVMAVLSSR -DAEDAEYDDALIAEAAELAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=UPI0005B88CDC --------AREIEQRLEARVGLAIYDTGSNQSW-LYKADERFPMASTFKAFACATLLHQVD -AGGRDLDQTVALAEADLVPYAPVMEKLVGQRVSLGELCAATMRTSDNLAANKVLDSIGGP -QQVTAFMRSIGDDTTRLDRREPELNQATPGDMRDTTSPAAIATSLRELVLGDALSASSRA -RLTAWLVENEVGGPLLRSGIPQDWRIGDRTGAGGYGSRGVVAVIWPPEREPIVAAIYLTG -TNATMDERNAAVAELGEALA--- ->[subseq from] Beta-lactamase class A n=2 Tax=Microbacterium sp. SLBN-1 TaxID=1489561 RepID=A0A542GRB8_9BACI ------ETFANIEDKYDARVGIYAIDTGSDRTI-DYRSEERFAFTSTYKALAATLVLKQNT ---MEELEEVITYTEDDLVSYSPITEKHVDTGMTLSELGEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQADRYETALNEFTPGDPRDTSTPAALATSLQGFAVGDLLPDDKRK -ILIDWLKGNATGDTLIRAGAPEGWTVADKSGAGRYGTRNDIAVVWPPDREPIILAIMTRH -DTEDADYDDALIAEVAEVTLE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2K4_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQT -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Prauserella sp. YIM 121212 TaxID=1477506 RepID=UPI000D76E816 ----AHREFGELEQRFDARLGVYAIDTGTGREI-AHRAGERFAYCSTFKALATAALLSERT ---VAELDVVVPYTEADLVTYSPVTEKHAGAGLPLREVMDAAVRYSDNTAGNLLLRELGGP -KGLQAALREVGDETTHVDRYEPELNEATPGDIRDTSTPRAMAGTLRAYALADALTAEKRA -IFVDMLRRNLTGDELIRAGVPDGWVVGDKTGNGDYATRNDIAVVWPPDRAPIVLALMSSR -SEKEAEHDNALLAEATKTVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=UPI0007C700D0 ------DSFASMESERAARLGVYAVDTGSGRTV-AYREGERFPMASTFKGLACGALLRDHP -LSTGFFDQVIHFSRDELVEYSPMTEQRVDTGMTVAELCEATITLSDNTAGNKVLELLGGP -AGFTAFLRSIGDEVTRLDRWETELNSAVPGDERDTTTPAALAADYRALVLGDVLGEPERA -QLKSWLVANTTGDQRIRAGVPADWTVGDKTGSPAYGGTLDVAIAWPPGLAPIVIAVLTAK -SEPDAEPDNALVVDATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE12344 ---DVDKQLADLEKKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGMEKLDRRVTYGKDKVVTYSPATEKHADTDMTVGELCGAAITLSDNTAGNLLLESFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAAKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVANTTGNNRLCAGLPKEWKTGDKTGTGNNGSYADIAVIWPPDRGPVLVTTFVAD -ATAPAKDVETVFAEIGKIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000A11DE33 ------KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI21_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVXDKTGAGDYGTTNXIAVIWPEDHAPLVLVTYFTQ -PH--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1EA869 ----LRAQWAEIERGTGGRLGISLLDSATGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKMPLAQPVKIGASDMLSHAPVTERHVGSALSVGELCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI0008728BDE -----NHSFVKLEKEYDAKLGIYALETGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDLRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTHDTSTPKALATSLQTYALGDILSTEKQN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADVTKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. LK2 TaxID=1628206 RepID=A0A0J6L6Q7_9BACI -----NQSFVKLEKKYDAKLGIYALDTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKKNTTGDNLIRAGVPGEWKVADKTGSGPYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIAGATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinobacteria bacterium OK006 TaxID=1592326 RepID=UPI0006BB2E17 ---DTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLASGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF6C10D -----NHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPGDIRDTSTPMALATSLQTYALGDILPIEKRN -FLIDLMKRNTTGDNLIRAGAPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDVKYDDKLIADATKIVLN-- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. kraussei Quebec TaxID=1398203 RepID=A0A077PCE2_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYRAHERFPLCSTSKMMAVSALLKKSE -TDEGLLNQRIHYQQSDIVEYSPITEKHLQDGMTLAELSAATIQYSDNTAMNLLIDQLGGT -HDVTRFARSIGDNSFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT -QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPWILVTYFTQ -PNKDAEAHPDVLAAAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E2F9D23 ---KSDQEFAKLEEKYDANLGVFALDTGTNKTV-TYHSDERFAYASTHKALAVGALLQRKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. TaxID=1884818 RepID=A0A5B9T713_9ESCH -------EVKDVEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQ--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium versatile TaxID=2488639 RepID=UPI00102F1AE1 --pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGP -QELTIFLRKAGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -GQATIEERNKQIAEIGTSLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561W3K4_9ACTN ---AAEQEFQRLEKTFGARLGVYAVDTGTGRTV-EHRSDERFAYASTWKALAAAEVLDDTT ---DAELDRVVRYPARDLVAHSPITEKHVAEGMSLRAVADAAVRYSDNTAGNLLLRHLGGP -EGFERKLRAVGDTTTDAARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD -VLRGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DTKDATPDDALIAEATRVVVA-- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI0003423B24 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRASVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-455 TaxID=1463908 RepID=UPI0004BF4D29 -----TARLRELEQEHTARLGVYARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD -RDGEFLARRVYFTQDDVDKYSEVTKHHVATGMTIGELCDATIRFSDNTAGNLLLEELGGP -TAVTRFCRSIGDPVTRLDRWEPELNSAEPWRVTDTTSPRAIGTTYARLVLGTALEPRDRG -RLTDWLLGNTTSVERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPGGTPIVLSVLTTQ -PEEDAPADNALVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00119E23ED ---KSDQEFAKLEEKYDANLGVFALDTGTNKTV-TYHSDERFAYASTHKALAVGALLQRKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora cyanea NA-134 TaxID=882082 RepID=H5XLN5_9PSEU ----VRAELRALESRHAARLGVHAINIRSGAVV-SYRAHERFPMCSTFKTLAVAAVLRDLD -HDGEFLDSWVHYTEDDLVPNSPVTENHVGRGMRVEQLCAAAIRKSDNTAANLLLRRLGGP -GGVTRFCRSLGDPVTRLDRYEPELSDAVPGDPRDTTTPAAIAADYRRLVLGRALCPADRE -RLTTWLTESVTSDTRFRAGLPSHWRLADKTGSGGYGTANDVGVAWTGDGAPLVLAVLSTK -HVEGAEWDDELVARTASVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A068N7C4_BACCE -----------------ARLGVYAIDTGTNQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAVATNLKDLTVGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDVAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIAEAAEVVVNAf ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A1B1WXK4_ACIBA ----VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLTSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=6 Tax=Bacillus TaxID=1386 RepID=A0A2A9YG25_BACCE -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000B4127ED -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus group TaxID=86661 RepID=UPI000BEDA2C0 -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=A0A0M1MQA2_9XANT ---MLRAQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A059WWD7_9BACT -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI000B4365CF ------KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces eurocidicus TaxID=66423 RepID=A0A2N8NUG6_STREU --qEAERAFGELESEYDARLGVYAVDTGSGRSV-AHRPDERFAYASVCKAFLAGAVLRKNT ---LQQLDRRVRYGRDVPVGHSPVTAEHVGGGMTLRELCDAAVRHSDNGAANLLFDELGGP -KGLQDALAAIGDHVTRADRYETDLSEAAPGDPRDTSTPRAMAADLRAFVLGDALAADRRP -LLTDWLKRNTTGDTLIRAGVPAGWQVGDKTGSGGYGARNDLAVLWPPRAAPLVVAVFSGR -TAKDAKADDTLIARAAEAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BEC645F ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKYVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPENKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. Root1220 TaxID=1736432 RepID=A0A0Q6UC44_9RHIZ --dEIERRMGALEKAIGGRIGVSAMDTKTSISF-GYRQTEPFPLCCTFKVLAAGLVLARVD -KGEESLERRVVYAKEKLVSYSPETERHVGGEMSVGDLCKAAITLSDNTAGNLLLESFGGP -KELTNWLRTLGDGSTRLDRWETDLNEAKDGDPRDTTTPDAMLDTLGNIALGTVLSEPSQD -QLAEWMVASTTGGARLRAGLPDTWKAGDKTGTGDNGSAADVAIIWPPGHGAILVAAYMTQ -TTAPMSEINPVFAEIGRIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000CDB51C9 ---ELRYKWAEIERGSGGRLGIGLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLVGDP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAAAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF732D2 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILKEMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A242XBH6_BACTU --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRHNERFAFVSTYKALAAGVLLQQNS ---IDTLNEVIKFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFHKIGGP -KGYEKALRQIGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVLVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. 2MFCol3.1 TaxID=1246459 RepID=UPI0003684D58 ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWMVANTTGNERLRTGLPETWKIGDKTGTGKSGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFGEVGRIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BDBA14 ---DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP -KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDNWSVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR -DGEDDAYDNRLLAKAAAVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax kalamii TaxID=2004485 RepID=A0A235EJL7_9BURK ---AWNDALATIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGRERLDARVHYVATDVVAYSPVSGPRAGNGLTVGELCAATVSLSDNTAANVLMARHGGP -AGFTAFVRSLGDQVTRLDRTEPTLNEAAAGDPRDTTTPLAMLQTLQKLVLGDALSPASRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR -STASAEQRDAAIAQVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Cmuel-A718b TaxID=697328 RepID=A0A1C5D9A2_9ACTN -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A243GP90_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKKDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000942A2D3 --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPEDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. OspMP-M45 TaxID=1115570 RepID=A0A1A9CY88_9ACTN ---DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP -KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDNWTVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR -DGDDDAYDNRLLAKAAAVVVR-- ->[subseq from] class A beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=UPI000353B2E1 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T7F8_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQT -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009AE2183 ------KKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRLETDLNSAVPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSSR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4E3_ECOLX ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQ--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE1DB79 ----ADVRLATLEKATGGRLGVSVLDVAMNISF-GRRQEERFAMCSTFKMLAAACILARVD -NGEERLDRKIAYSKADLVDYSPMTENHTEDGMTVAELCEAAVTVSDNTAANLLLASMDGP -EGLTRWLRGIDDQVTRLDRIEPELNEAKKDDPRDTTTPQAMLTTMGKLLLDDALSDTSRD -QLTAWLVGNKTGDKRLRAGLPKAWKVGDKTGTSATGAIGDVAIVWPSPNRPILVTAYIAE -ATKPAKELEYIFAEIGKMV---- ->[subseq from] Beta-lactamase n=1 Tax=Labrys okinawensis TaxID=346911 RepID=A0A2S9Q965_9RHIZ ----FAGAIRRIEGGVGGRLGVAALDLKSGVRL-AYRSDELFPLCSTFKLLVAAAVLARVD -QGRERLSRQVPIEAARLLPNSPITARHAGGRLTLAELCAAAITVSDNLAGNLLLEVVDGP -AGLTRYLRSIGDLVSRLDRWEVELNESLPGDPRDTTSPAAMLADLQRLLVGEALSPSSRS -RLTAWLKASRTGDTRLRAGLPAEWAFGGKTGTGERGSTNDVAIAWPPGRPPLLIAAYLTG -TTAAADRRNAALAAVAKAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas monteilii TaxID=76759 RepID=UPI0011A397A7 ---AVRQRLATLERTHGRTLGLWALETGSGQRL-AYRADQRFAFCSAFKVLLAGAILQRNE -AEPGLLAQHIDYDAATLVTYSPITQDHLETGIRVADLCAAALQYSDNTAANLLLAQVGGP -AGLTAFARRLGDVVFRLDRDEPTLNTALPDDPRDTTTPLAMGMTLERLLVGKALTVPSRH -QLQAWLEGNTTGASRIRAGVPGDWRVGDKTGTGDYGVANDVAIVWPPGRAPWIVVVFTRG -PDPSSSGDSALIAAAMREVVGV- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI00097159A7 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFHPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG5X1-1 TaxID=1053189 RepID=J8ATP3_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSEQVEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI0005BA8EEC ----TARQLAELERNAGGRIGVFAQEVDSGRSL-AYRANERFPMCSTFKLLLVGALLQRSA -TQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEELGGP -QEVNRFARSLGDGLTRLDRIEPELNRAEPGDPRDTTTPAAMTANLHALLFSPLLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG -SPAMMDERNAVIAAVARVAAAEf ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas hortorum pv. hederae TaxID=453603 RepID=A0A2S7E0N6_9XANT ----LRARWAEIERGTGGRLGIGLLDSATGKRI-GQREDERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -QGLTAFLRGIGDTQTRSDRHEPEMNRFAQDDPRDTTTPAAMALTLRTLLLGDALQPVSRK -QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGTDTRNDIAILWPSKGAPLLLTTYLNG -ASVDSDARDAALKAVAQAVASY- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas badia TaxID=265291 RepID=UPI0003F74AEF --------WQAIETASQGRLGVAVLDVASGAFS-GNRLDERFPMCSTFKWLAAAQVLQRVD -QGHEQLKRRVRFGKEVLLPWSPVTEQHVDDGMTVGELCQAAVAMSDNAAGNLLLQSLGGP -RGLTRFAREQGDSVTRLDRWEPQLNESTPGDPRDTSSPRAMAGLLQRLVVGQALSRGSRE -QLAQWLRDTKTNAQRLGAGLPALWRVGSKTGTGPHGSTNDVGVYWREGRPPIVVVAFLTE -SAASLAVRETAIAQVAKAVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodobacteraceae bacterium LNNU 3342 TaxID=2605434 RepID=UPI00123CA4C0 ---TIAEAARAIEADLGGRVGVALRRKGDGEVI-GYRSDERFPLSSTFKAPLCGAILALVD -AGEEKLDRVVGYTADDLVTYSPVTETQVESGMSVAELCDATITLSDNTAGNLLLERVGGP -EGFTGYLRAIGDETTRLDRWETELNEGAPGDDRDTSTPEAMTATLEALLFGETLSEASRR -QLEAWMQADQVADELLRASLPEGWVIGDKTGAGGHGSRSIIAVIRPPHDEPWLAAVYLTG -NAADMPTRNRAIARIGAAIV--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1V8Q7_BACCE -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKKDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9IA12_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETGLNEALSGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQI----------- ->[subseq from] class A beta-lactamase n=2 Tax=Xenorhabdus khoisanae TaxID=880157 RepID=UPI00069ED321 ---QLIHQLSILEKNANGRLGVVLIDTSDHSTF-AYRANERFPLCSTSKFMAVSALLKKNE -ANDHLLNQRIHYQQSDLVEYSPITEKHLKNGMTLRELGEATMQYSDNAAMNLILNQLGGP -NEVTQFARTIGDNDFRLDRKEPDLNTAIPGDERDTSTPQAMANSLYHLALGNTLETAQRE -QLVAWLKGNTTGGASIRAGVPENWVIGDKTGRCSYGTINDIAVIWPTNRSPLVLVTYFTQ -PNQNANARPDVLAEAARIVTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193BWT1_AMYOR ---QFHDRLLELEKKFDARLGVYALDTEGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVTYARDDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -GELTAFARSIGDTVTRMDRIEPAITEAAPGDPRDTTTPRAFGTDYQKIVLGDTLTADKRD -FLSDLLRRNVTGARRIRAGLPGGWTVADKTGTGEYGTMNDFAIVWPPGKAPIVVAIMSSK -AAKDAPYDEALLAEAAKYVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00114E3170 -----NHHFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQDFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDISIIWPSKGDPIVLVVLSSR -DKKDADYNDDLIAETTEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0006E17E35 ---KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGAVLKQNS ---LREMERRVRVRPQDLEDYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP -KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALATDLRAFVLGDVLPGKKRE -VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPVTLAVMSRR -DTRDAEHDDALIAEAAEVAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=A0A368XD71_9BURK -haQAERALAALEQGFAGRIGVCALDTADGALL-GQRADERFPMCSSFKAVLAAAILARSS -TEPGLLAEQVRYTRGDLLAHSPVTTQHLAQGMRVDALCEATVQTSDNAAANLLLQRMGGP -AGLTAFMRSIGDAQFRLDRWELELNSSLPGDPRDTTTPRAMADSLRKLVVGDALAPAQRD -QLATWLRGTVTGAARIRAGMPAGWVVGNKTGTSGYGSAIDVAVVWPPARAPLVLTVFTTR -HAADAQALDAPIAQAARIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0007CC0F71 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDKGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces netropsis TaxID=55404 RepID=A0A445N4B3_STRNE -----AGEFKELERKFDARLGVYAIDTATGREV-AYNDGERFAHASTFKALAAGAVLRKYS ---LSGMDRVVTYSKDDLVDYSPVTEKHVETGMSLDELCDAAVRFSDNTAGNLLLDALGGP -KALDAALEEMGDHETRMERREPELNRWAPGGTQDTSTPRALAKDLRAYVLGDALGKSEKA -RLTKLLRTNTTGNELIRAGVPKGWVVGDKTGAGQYGTRNDIAVVWPPDAAPIVMAIMSNR -NKKDAPYDNKLIAEAASVVT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8Z162_BACCE -----NQSFVKLEKEYDAKLGIYALNTGLNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IKDLDQRIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKLLRDIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKQN -FLIDLMKKNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143E7BB5 ----SAQAFKDLERKFDARLGVYAIDTGTGREV-SYHQDERFAHASTFKALAAGAVLQKYS ---LPGMDKVITYSRDDLVPNSPVSEKHVDTGMTLRALCDAAVRYSDNTAANLLFDSIGGP -KGLDSVLEKLGDHTTRMVRHEPELNDWSPNDTRDTTTPRAFAKDLRSFVLGDTLPRRERA -QLAKWLQTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAILSNR -PQKDAKYDDALVAEAASVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. X1(2014) TaxID=1565991 RepID=UPI0011A4C0A3 ---HIHREFAELESKFDARLGVYAIDTGTNRTV-SYRPHDRFAYASTYKALAAGALLKHYS ---IDQLNELVTYNSEDIVSYSPVTQLHVDTGMTLREVIEAAVRYSDNTAGNLLLEKLGGP -KGFETALRQIGDNVTQVDRYEPDLNSALPGDTRDTSIPKSLATSLKAYAVSDLLSMDKRK -ILTDWMQGNKTGDALIRAGAPTGWKVDDKSGAGSYGTRNDIAIVWPPNRAPIVIAVLSSR -DTKNATYNNTLIAEAARVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CMU55-4 TaxID=2717028 RepID=UPI00140A7C12 ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFARALRDVGDRVTRPVRIEPELNAATPGDERDTSTPRALAGSLRAYTLGEALPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDSAPIVLAVMSSR -GSRDAKPDDTLVAEAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DC028C5 -----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSTRDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD -VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DRKDATPDDAVIAQATRVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFC9EFB -----HNSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEGAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A4R1EQ42_BACCE -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLRKIGDSVTNPERFEPELNEVQPGDIRDTSTPMALATSLQTYTLSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -ANEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS017274 TaxID=2033488 RepID=A0A2A8TJC4_9BACI -----NHHFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQDFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDISIIWPSKGDPIVLVVLSSR -DKKDADYNDDLIAETTEEVMK-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces TaxID=1883 RepID=A0A542WCM2_9ACTN -------SLTDLEREYDARLGVYALATGTGATV-VHRADERFAFCSTFKTLAASAVLDRDP ---LSRLDRRVTYTRADLVPHSPVAEKHLATGMTVRQLCDAAIRFSDNAAANLLLRDLGGP -RAVTAHLRRLGDRVSRLDQSEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPGAKRD -LLADWLVRNTTGGRRIRAGVPRDWRVGDKTGTGEWGRVNDVAVLWPPSGAPLVMAVLTDR -PGRADTTDEALVAEAARRVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFC6B55 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKLVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2V2H6I9_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPEDVHDTSAPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKRA---- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus ihbetae TaxID=1870820 RepID=A0A1B2DYU7_9BACL -----DSLFKSLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLLQNS ---IEEIDEVISYSAEDLVTYSPITEKHVSTGMTLRDIMDAAIRYSDNTAGNLLLEQLGGP -EGFEAALRQIGDTVTQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPKDKQT -ILTDMLRGNTTGDELIRAAVPEGWAVGDKTGAGSYGTRNDLAIVWPPEGDPVVLAVLSSR -DTQDAEYDNALIAKAAEAAL--- ->[subseq from] class A beta-lactamase BlaP n=1 Tax=Bacillus paralicheniformis TaxID=1648923 RepID=UPI00102DCF72 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKGAKYDDKLIAEATKVVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. (strain L5) TaxID=648999 RepID=UPI0001C45D0B -------ELAALERRSGARIGVFALDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVVRYRRADLVAHSPVTERHVETGMTLRDAAEAAVRYSDNTAGNLLFDALGGP -AGFERALRDVGDQVTRPARTEPELNAATPGDERDTSTPRALAGSLRAYTLGETLPPADRD -LLLGWMRASTTGSGLVRAGVPAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVMSSW -DSRDAEPDDALVAQAARVTV--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF8B47E ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEGTPGYIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. raphani 756C TaxID=990315 RepID=G0CCH4_XANCA ---ELRYKWAEIERGSGGRLGIGLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDVALKAVAEAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5EN82_9ACTN ------AQFAALERKHGARLGVYALATGSGLSV-AYRADERFAFCSTFKALAAAAVLHRNP ---LSHLDTRVTYTKADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -AQLTAYLRELGDTTSRMDQYEPELNRDRPEDPRDTTTPRAIAADYRKLVLGDALTAGRRA -LLKDWLERNLTGAKRIRAGLPEGWAVADKTGTGDYGRANDIAIVWPPHTTPLVVAVMSDR -PGYDTPPKDALIAEATTQIV--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Salmonella enterica I TaxID=59201 RepID=A0A0S2IHT3_SALTM ---------AELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYST- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0004F13DD5 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFSPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1G6IHS6_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPEDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPPNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas gei TaxID=1395960 RepID=A0A4S1X984_9SPHN ---EFRNAVGAVERASGGRLGLSILDTATGDRF-GWRASERFPMCSTFKFALAAAILKQVE -AGRETLDRRIKVAAADIVSNSPFCEKRVGASASVRELCQATITLSDNSAANLLLRTIGGP -DGFTRRLRAFGDPVTRLDRWETDMGEAKPGDVRDTTTPQAMADLARHLVLGRALAPTSRD -QLTAWMKDTRTSRTSLRAGLPAGWTVADKTGAGGYGTDNLLGIVWPPRRAPLVVASYITG -GSLPLEQSRPLHARVGRAIA--- ->[subseq from] UPI0010428532 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0010428532 --tEMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFYPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JKS001846 TaxID=1938743 RepID=A0A1W2GPU6_9BACI --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGL -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIAMNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0Q8EAV6_9ACTN -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRGGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAEPERA -RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A386UWD8_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNKVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes brasiliensis TaxID=52695 RepID=A0A4R6JBH2_9ACTN ------QRFGELERRFGARLGVYALDTGNGRTV-THRADERFAHASTFKALLAAVLLRRLS ---DGDLRRVIRYTRADLLEWAPITEKHVKTGMTVDALIAAAVQHSDNTAANLLLRLTGGP -EGVQRELRKIKDNTTDLSRYEPTLNTAVPGDKRDTSTPRALGADLRAFVLGDVLPAPRRQ -KLTDLLLGNTTGDTYIRAGVPSGWKVGDKTGSGGYGTRNDIAVVWPPTGSPVIIAILSDR -GRPDAPSADALIAEATRAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NRY5_9ACTN ---AADQEFRRLEEQFGARLGIYAVDTGSGRTV-EYRADDRFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETVLNEGTPGDKRDTSTARALAGDLRAYTLGVALQPADRD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DKKDATPDDAVIAQATRVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF29866 -----NHSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI000949FED8 ---MLRSQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012938722 ----SDREFAKLEDKYDANLGVFALDTGTNKTV-AYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BFB65B3 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-TYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQKITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPETIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus chungangensis TaxID=1229152 RepID=A0A3D8PNG0_9BACI ---ATNNDFSKLEDEFDATLGVFALDTGTNETV-TYRPDQRFAYTSTHKALAVGVLLQQKS ---IGDLNQRITYTHDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQVGGP -SGFKKALREIGDNVTNPERIEPELNEVNPGETHDTSTPRALAISLQAFTLGDVLPTEKRA -LLIDWMKRNTTGDTLIRAGVPEGWEVADKTGAGLYGTRNDIAIIWPPKGNPIVLAILSDR -NTKDATYDDKLIEQATRVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBF9EDE -----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSTRDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD -VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DRKDATPDDAVIAQATRVVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-35 TaxID=512030 RepID=A0A542RTB7_9BURK ---EWNETLASIERIAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD -QGRERLDARVHYAATDVVAYSPVSGPRAGNGLTVGELCAATVSLSDNTAANVLMARHGGP -AGFTAFVRSLGDQVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGDALSPASRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR -STASAEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A1 TaxID=148446 RepID=UPI000468E0F1 ---AASRQLDALEQGFDGRIGVAALDTGSGARL-LHRADERFPFCSSFKIMPVCALLARSA -KEPDLLSRVIRYRRQDLVINSPVTERHVDTGMSVAALCAAALQYSDNTAANLLIRLVGGT -AAVTAYARSIGDGSFRLDRMEIELNESVPGDARDTTTPAATAATLQRVLLGDALDASSRA -QLTDWMLGNRVGTARIRAGVPAGWRVADRTGTGAYATANDIAMLYPPHRAPIALAVYTTR -ERDNGDYDEARIAAVARVVVAAf ->[subseq from] class A beta-lactamase n=1 Tax=Lentibacillus sp. Marseille-P4043 TaxID=2040293 RepID=UPI000D0BDD35 -----DEKFAQLENEFDTRVGVYAIDTGSNQTV-EYQSDERFAYSSTFKVLAAAILLKQND ---IKNLEKVVTYTKDDLVTYSPVTEKHVNTGMTLLEISEAAIQKSDNTAGNLLLEAIGGP -DKFKQALRDIDDDVTQPERYEVELNEFMPGNKRDTSTPRAMATSLKKVALDDFLPDDKRE -VLIDWMKGNATGDRLIRAGVPEGWIVGDKSGAGSYGTRNDIAVVWPPNREPIVIVVMSRR -DTKNAEYDDALVAKAAKITLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008645BD5 -----NQSFAKLEKEYDAKLGIYALDTGPNQTV-AYHSDDRFAFASTSKSLAVGALLHKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0008174623 -----NNSFAKLEKEYDAKLDIYALDTGTNQTV-AYHANDRFAFASTSKSLAAGALLLQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILREIGDTVTNSERFEPELNEVNPGETHDTSTPEAIAKTLQSFTLGNALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000C05B7CD -----NKKFVQLEKKFYAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPKGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI000289A97B ---AAQTQLAALEQGAGGRLGVAAWRHGSAQRV-AYRADERFPLASTFKAMLAAAVLARSV -SQPGLLEQRVRYEKKELVSYSPITEKHLAEGMNVADLCAATLQYSDNSAANFLMRLLGGP -QAVTAFARSIGNTLFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLEHSLPAVQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKNADTNEDIITAATRIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Aureimonas jatrophae TaxID=1166073 RepID=A0A1H0MBJ1_9RHIZ ---RLDDVIRREESAIGARLGVAIHDTHDDVWW-RHRADERFPMCSTFKVLAGAATLKRVE -RGEEDLTRRISIAPDDIVTYSPVTEKRVGENMIMAEVLQAALTMSDNTAANILIDTLGGP -QSVTAFIRAIGDNTTRLDRRETELNEATPGDPRDTTTPEAMTRSLESLLLGNALQPTTRL -MLEGWMVANTTGGAKLRAGLPASWRVGDRTGGGAYGTMGDVAVIWPIDRKPVVASVYITE -TEASFDRRNEAIAAIGKALA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium etli TaxID=29449 RepID=A0A327XIG8_RHIET ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNITLGSVLSEPSQK -TLIEWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVTTAEINPVFGEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JKS001846 TaxID=1938743 RepID=A0A1W2GQX5_9BACI -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDTLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKKDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=H9AXM0_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSRNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANILLTTIGGP -KELTAFLHNMRDHVTRLDRWEPELNEAIPHDERDTTMPAPVATTLRTLLTVELLTLASRP -RLIDWMEADKVAGPILRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HIT-DPA4 TaxID=2615112 RepID=UPI001245D56C ----VTARLRALEAQHGARLGVFAHNLATRRTV-AHRADERFPVCSLFKTLAAAAVLRDLD -RHGETLARRVHYTADDLVENSKRTEEHLAEGMTIAELADAAIRYSDNTAGNLLLRELGGP -PAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALNRRDRA -LLTHWLLNNTTSDNRFRAGLPRTWTIADKTGGGFYGTNNDVGIAWTEDGTPLVLAVQTTF -PDEDAPYDHALIAETAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. EN27 TaxID=211464 RepID=UPI000851E273 -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS ---LDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KSLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDELIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas hydrothermalis TaxID=115561 RepID=UPI00054ACEFC ----ITAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP -EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ -QLQNWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE -TDATFEARNEAIASLGEVVQ--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ScaeMP-e83 TaxID=1758151 RepID=A0A1C4KHY2_9ACTN ----TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGKEEIISNSPVTEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGIGDQVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYALGSALPAEKRA -VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPDAAPIALAVLSRR -DTEDAEPDDALIAGAAKVALGAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEE72CF -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEELSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=B9UN52_ACIBA ----VLEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLTSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Massilia sp. JS1662 TaxID=1519190 RepID=A0A098UBL0_9BURK ---AAEAAFADLERRAGGRLGVAAWRRGGTKII-EWRGGERFPFCSTAKVMVVGTVLTQAA -RTPGLLGERVRYKKTDLVSWSPVTERHVDDGMTVADLCAAALQVSDNSACNLLLDRIGGP -AAVTAFARRIGDTAFRLDRRETELNSAVPGDPRDTTTPRAMAKSLEALLLDEALAPDARR -RLLDWMLANTTGKERIQAGFSSDCRVADKTGTGAHGTTNDVGIVFPPQGQPVIVAVYYTG -STSDS----KVVADAAAIVAR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ301 TaxID=2512145 RepID=A0A4Q8BM95_9ACTN ---ATTRRLKNLEREHDARLGVFAHNTRTGRTV-IHRADERFPMCSTFKPLAVAAVMKDRD -DGGRPLDERIRYSRSDLEAHSPVTGRHLAEGMTLRELCDAAIRHSDNTAANLILRELGGP -TAVTRFCRSLGDEVTRLDRWETELNSAEPGNVKDTTSPRAIGRTYMRLTLGDVLGRAGRR -QLTDWLKRNTTGDESLRAGLPEGWTVGEKTGAGEYGTHNDVGVAWTAHGEPVVLAVLTTK -KSADAEPDRALIAKTARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Myxococcales bacterium 68-20 TaxID=1895795 RepID=A0A1M3MWT0_9DELT ---HASRELAEIEAKVGGRIGVVALDTGTGREL-AYRPDERFAMCSTFKWVLAAAVLTRVD -RAQLSLDERVRYGEADLLEYAPVTREHVEEGLTIDALAAASVIVSDNTAANLLLAKIGGP -AGFTEFVRGLGDSVTRLDRNEEMLNRNAAGDPRDTTSPRAMVGTMRKVLCGDVLSSASRD -RLLSWLRACETGKKRLRGGLPEGWIAGDKTGTGMRGAVNDVAIASPPGRAPILIAAYTSD -GNASVEVLSAAHADIGRLVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. 68-29 TaxID=1895823 RepID=A0A1M3P3X5_9GAMM ---DVEARLAALERRHGGRLGVAILDTGDGRRF-GHRADERFLMCSTHKVLAVGAVLARVD -RGEESLDRRVVFGRDVVLSWAPVTSHRVGAPMSVAELCEATITVSDNTADNLLLASLGGP -PAVTAFARRLGDTLTRLDRIEPDLNAGGNGDVRDTTTPNAMLGSLRTLMLGDALSAASRD -RLAAWMRATRTGLDKLRAGVPGDWRAGDKTGSGANGESNDVAILWPPRRKPVLVTAYCVN -PAAGATARSAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 007/AIA-02/001 TaxID=2509009 RepID=A0A4Y9U7T6_9BACI --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGIATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces anulatus TaxID=1892 RepID=UPI0013DB433C -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---LGGLERIVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAGPERA -RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DC4ECA9 ---AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADDRFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DKKDATPDDAVIAQAAEVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=A0A3R7EHM8_XANCA ---ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAAAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F8673C -----AAALARLEEGLSGRLGVFAIDTASGATI-GHRASERFPICSTFKAVLAGALLARSV -REPGLLDERVRYTKADLIAHSPVTGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP -EALTAQARAWGDGTLRLDRWETELNSALADDPRDTSTPEAMARLLRTLAVDDGLPTAQRA -RLQDWLRGNTTGGARIRAGMPPAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL -EAQDAKPRDDVIAAASRIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A5C4TQ97_ACIBZ ----VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9X5N5_9ACTN ---AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYPARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADHD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLTSR -DTKDATPDDALIAQATRAVVA-- ->[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A127SF50_9BACT ----VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter calcoaceticus subsp. anitratus TaxID=107673 RepID=Q9JP71_ACIAN ----VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces noursei ATCC 11455 TaxID=316284 RepID=A0A1B2H383_STRNR -----AAELRDLERRYAARLGVYARNARTGQVV-AHRAQEWFAMCSTFKTVAAAAVLRDHA --HCAPLDKVIHYPARDILPYSPKTQEHVDTGMTVGDLCAATIQYSDNAAGNLLLRQLGGP -EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDPRDTTTPEALGTSYGRLALGRALTHDARE -QLVTWLKGNTTSEHRFRAGLPQHWVVGDKTGTGDYASANDVGVAWTGRSTPIVLAVLSTK -STKDAPVDEALIADAARIVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=UPI00047A62B9 ----LTPKIRRLEAKSGGRLGVACRIAGTTAQF-GYRENELFPMCSTFKTLAAALILHRVE -GGIEQLDRSIKVPHNAVVASSPTTKNHAGGEMTVAQLCEAAVTVSDNGAANLLLDSFGGP -AQLTAYLRSIGDKVTRLDRIEPELNESVPSDPRDTTSPLAMIDDYERLALGDSLSQKSRA -QLVEWLVANKTGDDRIRTGLPKGWKCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG -TKQSLARRNAVIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005AF3E35 ----LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDAALKAVAEAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium sp. NG07B TaxID=1538174 RepID=A0A2A6MCW2_9RHIZ ---DVTKLLAELEKRTGGRLGVAVLDTETNISF-GHRETERFAMCSTFKALAAACVLARVD -RGEEKLDRRITFGKDVLLPHSPVAEKHVGGNMTVAELCDAAVTISDNAAANLMLESFGGP -AGLTSWLRSIGDGTTRLDRTEPDLNEAKFGDPCDTTTPVAMLETIGKLAFGSVLAESSRR -QLVEWMVANTTGDARLRAGLPKDWRIGDKTGTSSTGAVSDIGFAVPKGRGPILITVYTGE -AKVEPAELNPLFAEVGKIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Psychrobacter sp. DAB_AL32B TaxID=1028414 RepID=A0A229G3K8_9GAMM ----ILEAVTNAETELDARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQAALSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSVKSRQ -QLESWLKSNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=H9AXM3_XANCE ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF6713D ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTARALATSLQKYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C01 TaxID=1945856 RepID=A0A1V3PKS7_9GAMM ----AVTRLAALERKYGGRLGVSILDTGSGRRA-VHRADERFLMCSTFKLLAVASVLARVD -RGAEQLDRRIVFGKESVLAWAPVTSHRTGGQMSVAELCEAAITVSDNTAANLLLASLGGP -ATVTAYARGLGDPLTRLDRIEPELNTGGPGDVRDTTTPNAMLADLRTLLLGDALSMASRR -QLVEWLRATRTGVDKLRAGVPGDWQVGDKTGSGAHGESNDIAIIWPPQRKPLLVTAYYAA -WPADSAGHDAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=3 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=H9AXM7_XANCE ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDAALKAVAEAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. BL6 TaxID=2585770 RepID=A0A5C4Q7X5_9GAMM ----ITAELARIEQALDARIGFAAHNLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALETEVSFEESDLVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP -EAVTAFARSMDDPITRLDRYETELNEATPGDERDTTTPNAMLATLEKLVLGDVLADESRQ -QLEAWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQPPTVAVFYITD -TEASFEERNAAIASLGEVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1N6PSQ1_BACCE -----NKSFTKLEKEYDAKLGIYALDTGTNQTV-VYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Polaromonas sp. 35-63-35 TaxID=1970418 RepID=A0A258NPI5_9BURK --------WRAIESLSGGRLGVAVLQTD-G-SIeGHRLDERFPMCSTFKWLAAAHVLQRVD -RGLERLDRRIPYGREVLLPHSPVTEKHVGKGMTLGELCHATITTSDNAAGNLVLAAGGGP -QGLTTYARSLGDGVTRLDRWETELNEATPGDPRDTTSPRAMAHLLKATLLGDALSMRSRE -QLSQWLVACVTNGQRLRADLPAEWRMGSKTGGGGYGSTNDVGIFWPPGRPPILVTAYVTN -TETSQADRNAAIAAVARRVTT-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6K431_9BACT ---EFAKRIAAIEAQTRGRIGVATVDTGSGKHL-DYRSEERFPMCSTFKFLAAAAVLKRVD -EKQEKLERFVPYDAKDILEYAPVTKTHLEEGMTLGALCGAAVAQSDNTAGNLLLYAIGGP -VGLTNFARDLGDNMTRLDRKEPELNSAGPGDERDTTTPASMLADMHQLLLENGLSASSRQ -QLEAWLRANETGSAMIRAGVPGNWIVGDKTGRGANGATNDIAIMRPPNRAPILLTIYSVG -STGSANDRTATIAEVAKIVAGEf ->[subseq from] Beta-lactamase n=1 Tax=Hydrocarboniphaga effusa AP103 TaxID=1172194 RepID=I8T4V7_9GAMM ---------RGIEDEVGGRFGVAVLDTGSGRLA-GHRLDERFPMCSTFKWVAAALVLQRVD -AGQEQLQRRIRFGREVLLSHSPVTEQHVRGDMTLAELCAATISVSDNAAGNLLLDSFGGP -AALTRYVRGLGDSVTRLDRNEPTLNESLPGDPRDTTSPRAMAGLLRTLLLGDALSAASRA -QLRRWMEATQTSDRRLRARLPAGWRLASKTGTGPRGSTNDIGVYWPPGAPPLVVAVYQTG -SAAPLSALEAAIAGVAARV---- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DC2D250 ---AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSAQDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTGTARALAGDLRAYTVGVALQPADRD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DKKDATPDDAVIAQAAEVVVA-- ->[subseq from] UPI000F044F0E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000F044F0E ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLDGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes brasiliensis TaxID=52695 RepID=UPI00105F307F ------QRFGELERRFGARLGVYALDTGNGRTV-THRADERFAHASTFKALLAAVLLRRLS ---DGDLRRVIRYTRADLLEWAPITEKHVKTGMTVDALIAAAVQHSDNTAANLLLRLTGGP -EGVQRELRKIKDNTTDLSRYEPTLNTAVPGDKRDTSTPRALGADLRAFVLGDVLPAPRRQ -KLTDLLLGNTTGDTYIRAGVPSGWKVGDKTGSGGYGTRNDIAVVWPPTGSPVIIAILSDR -GRPDAPSADALIAEATRAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Alkanindiges illinoisensis TaxID=197183 RepID=A0A4Y7XFG6_9GAMM ----VNVFLSQLEKQAQGRLGLSAMNTANQMRI-DYRASERFPLCSTFKLVAVAAILQQSM -HNSILLQQHIDFTFQQVQDYAPITAQHVDRGMTVSELCAACISYSDNAAANLLLQILGGP -AALTRFARSIGDHNFRLDRWEPALNTALPQDERDTSTPAAMTDTLQRLLLGNVLAPTQRE -LLLYWLKNNTTGNARIRAGVPNSWIVGDKTGTGAYGTSNDIGIVWPTQQAPIILAIYFTC -PDKTAKPNDAIIASASKIVCQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. MBT66 TaxID=1444769 RepID=UPI0007C777E1 ---ELADRFCALERSHSARLGVFAQDTVTGRTV-AYRADELFPMCSTFKTIAVAAVLRDLD -RDGTFLAQRRLYTATDVAQYAPITGLNLEAGMTVEELCAAAIRYSDNAAANLLLRELGGP -DALTRFCRSIGDRVTRLDRWEPALNSAEPGRLTDTSSPHALGRTYARLTLGQALDPADRQ -RLTGWLLTNTTGTNRLRAGLPPTWRVAEKTGTGSYGTTNDVGVTWPPDGRPIVVAVLSTK -HTADAPANEPLIAETARIVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3862 TaxID=632858 RepID=UPI000BAF7631 ----ATKAVEALEARNGGRLGVMVLDIGTNAAI-EYRADELFPITSTFKFLAAAGVLKAVD -DGKAKLDDRIVYAASDVEQYSPITKDHAGEGMKLEDVCAAAVVWSDNTAGNLLLRMLGGP -QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRAALGDARRILLGDALSPASRK -RLEAWLIEDKVGAARIRAGLPATWGIGDKTGSGDNGTTNIVAILWPPEGAPILVAVYYTG -STAPRASREAVHRDMARIIVETf ->[subseq from] Beta-lactamase class A n=1 Tax=Rubrivivax gelatinosus TaxID=28068 RepID=A0A4R2MB92_RUBGE -------AFGAIERSVAGRLGVWAYDLETGRSL-GHRQDERFPMCSSFKWLLAAAVLARVD -RGQERLERRIVFGREALLEYAPATSHRAGGAMTLAELCEAAVTLSDNTAANLLLDTLGGP -AGLTAWVRTLGDRRTRLDRREPDLNEARPGDERDTTTPAAMVLALRQTLFGGGLSRRGAD -LLLQWMTASTTGLKRLRAGFPADWRVADKTGTGGEGTTNDVAVVWAPGRAPLLLAAYLTE -SPAAIEAREAALARVAAR----- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. PC23-8 TaxID=2012679 RepID=A0A255HG52_9BURK ---QAQAQLAALEQAAGGRLGVSALHTGSGARV-EHRADERFPMCSTFKAMLAAAVLARGS -SEPQLLDKLVRYEAKELVSYSPITEKHVATGMRVAELCAATVQYSDNSAANFLMKLLGGP -QAVTAYARSIGNQVFQLERWETELNSAIPGEVRDTTSPAATVHSLDGLLLGASLPAPQRQ -QLDIWMRGNTTGDQRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPSGDAPLVIAIYYTR -EQKNAPINQHIITKATRIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces yokosukanensis TaxID=67386 RepID=A0A101PE04_9ACTN ---RAEAELAELERRHGARLGVYARNARTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDQT --CRTPLDTVIHYPPRDILAHSPRTEEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP -PGLTRFFRSLGDEASRLDRWEPDLNTAIPGDPRDTTTPGALGRSFERLTLGRALARADRE -RLVTWLKGNTTSGARFGAGLPRGWALADKTGTGDYGTANDIGVAWTTRGTPVLLTVLSTK -SAQDATADDALVAEAARILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI00102EA35D -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEIIHYSKDDLVTYSPITEKHLETGMSLKEILEAAIRYSDNTAGNKLLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKTLATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A2X2DIQ7_PROMI ----VLEAVTNAETELGARIGLAAHDLETGRRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=2 Tax=Xanthomonas vesicatoria TaxID=56460 RepID=F0BKK8_9XANT ----LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKLSLAQPVKIRASDMLEHAPVTKGHVGGALSVGDLCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLHTLLLGDALQPASRT -QLTDWMIDNRTGDDCLRAGFTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces fungicidicus TaxID=68203 RepID=A0A494UUV2_9ACTN -------SLTDLEREYDARLGVYALATGTGATV-VHRADERFAFCSTFKTLAASAVLDRDP ---LSRLDRRVTYTRADLVPHSPVAEKHLATGMTVRQLCDAAIRFSDNAAANLLLRDLGGP -RAVTAHLRRLGDRVSRLDQIEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPGAKRD -LLADWLVRNTTGGRRIRAGVPRDWRVGDKTGTGEWGRVNDVAVLWPPSGAPLVMAVLTDR -PGRADTTDEALVAEAARRVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Telmatospirillum sp. J64-1 TaxID=2502183 RepID=UPI00115DFC4A ---EIQALFAELESQHGGQLGVMVHNLGTGATA-CYREDERFAMCSTFKVLAAAYVMARVD -RGQESLDRRVVFSQEDIVSWSPVTEKRVGGEMTMAEICDASMTISDNTAANLQLASFGGP -SALTAYLRRLGDNVTRLDRFETELNENAPGDRRDTTTPAAMAETLRKIFFEDVLSKSSRA -QLASWFIANKTGDKRLRAGFPDTWLVGDRTGTSGNGAAHAVAIAWPTDRAPVIVTSYYNN -PSSTDEVWNAVHEEVARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Janthinobacterium lividum TaxID=29581 RepID=UPI001407385B ---AAQTQLAALEQAAGGRLGVAAWRQGSDLRV-AYRADERFPLASTFKAMLAGAVLARSV -SQPGLLDQHVRYEKKELVTYSPITEKHLANGMNVADLCAATLQYSDNSAANFLMTLLGGP -QAVTAFAHSIGNTVFQLERWETELNSAIPGEVRDTASPASMAHSLQQLLLENSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWQVADKTGSGAYGSVNDIGVAYPASGAPLVIAVYYTR -EQKKADTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Stappia indica TaxID=538381 RepID=A0A285SQC4_9RHOB ---DIEGRLAALESKQGGRLGIAIHDVASGQTF-GNRLNERFLMASTFKLMLTAFVLARVD -REEEQLDRRIPFTKRDLVSWSPGTEKHAGGPLTVAELCEATMTLSDNTAANLLLKSFGGP -AALTGFARSLGDETTRHDRTEPALNADGPDDERDTTTPAAMAETLRKLLFGDALSRRSRD -RLTAWMVTNRTGDARLRAGFPADWLVGDKTGTSGKGHANDIGVAWPSGRGALIVTAYCEM -PKAEAKARDATMAEIARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF109F4 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKENAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=3 Tax=Salmonella enterica TaxID=28901 RepID=A0A077KT80_SALER ---QMVQQLSALEKSANGRLGVAVIDTGSGAIA-GWRMDEPFPMCSTSKVMAVAALLKQSE -QTPELMSQPQPVASGDLVNYNPITERFVGKSMTFDELSAATLQYSDNAAMNLILAKLGGP -QKVTAFARSIGDDKFRLDRNEPSLNTAIPGDLRDTSTPRAMALSLQKLALGDALGQVQRE -KLSHWLRGNTTGAASIRAGLPSGWSVGDKTGSGDYGTTNDIAVVWPTGRPPLVIVTYFTQ -PQQQAESQRPVLAKAAAIVASHy ->[subseq from] Class A beta-lactamase n=1 Tax=Gammaproteobacteria bacterium ESL0073 TaxID=2070539 RepID=A0A2Z3I9Q1_9GAMM ----TLDKIKEIESQLNARVGYVQLDFSNGLLIeGYRSQERFPMMSTFKVLLCSAVLSRVD -SGLEQLDRRVRYHQSDLIEYSPVTKEHLSEGMTVAELCNATITMSDNTAANLLLSSIGGP -KELTKFLRKVDDQTTRLDRWEPMLNESLPEDERDTTTPEAMSKTLFTLLTGKALTASSRQ -QLIDWMEADKVGGPLLRSVLPKGWFIADKTGAGEHGSRGIVAVLGPNGKPYRIVIIYLTG -SSASMDERNKQIAEIGASLIQHw ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas vesicatoria TaxID=56460 RepID=UPI00073209CA ----LRAQWAEIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKLSLAQPVKIRASDMLEHAPVTKGHVGGALSVGDLCRATMIYSDNPAANLLFPLIGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLHTLLLGDALQPASRT -QLTDWMIDNRTGDDCLRAGFTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio ascidiaceicola TaxID=285279 RepID=UPI000B8320B7 ---ELMDTVTRLESEVGGRIGVVLQHTGSEWGI-EHREDERFPLASTFKALLCGAVLSRVD -RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNTAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPALNEAKHGDSRDTTTPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDTGAPYLAAVYMMG -SDASFKQRNAVIAEIGKAMIE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KNA3_9PSEU ---QFHDRLMELEKKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLHRNP ---LSHLETRVRYSRDELMKHAPITGQHVSTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AELTAFARGLGDTVTQMDRLEPAITEATPGDPRDTTTPRAFGTDYRKIVLGDALPDDKRD -FLRDLLQRNTTGAERIRAGLPSGWTVADKTGTGEHGTLNDIAVVWPPDKAPIVVAIMSSK -AAKDAPYDQALLAEAAKYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5D4RU48_9BACI ---DLDETFATIESDYDARVGVYAIDTGSDQTI-AYRSEERFAFASTYKALAAALVLKQNT ---MEELEEVIAYTEDDLVSYSPITEKHVDTGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDEVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGGLLPDDKRE -ILIDWMKGNATGDTLIRAGAPDGWTVADKSGAGRYGTINDIAVVWAPDREPIIMAIMTRH -DTEDADYDDALIAEVAEVTLE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHX6_KLEOX --dTLQKKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SHPDVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGGGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NP10 TaxID=1141731 RepID=A0A433DWS8_9ACTN -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTMKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALHPPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces achromogenes TaxID=67255 RepID=UPI00099D4A8A ------AELAELERRYGARLGVYARNVRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG --DRAPLDRVVHYPPRDILPNSPRTQENLETGMTVAGLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFLRSLGDTVSRLDRWEPELNTAIPGDVRDTTTPEAIAGSLERLTLGRALRRADRQ -RFTGWLKGNTTSEERFRKGLPPAWVVADKTGTGDYATANDIGVAWTTRGTPVVLAVLSDK -SAKDAPVDQALIAEAAAVVAR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDA3_ECOLX ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDQQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQI----------- ->[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. Root142 TaxID=1736461 RepID=UPI00070FA2C4 ----VDTRLAELEKRTGGRLGVSVLDMETNVSF-GRRESERFAMCSSFKTLAAGFALARAD -QGAEKLDRRIVVAQKEIVAHSPVTEKHVGGEMTIAELCAATLTTSDNAAANLLLENFGGP -PALTAWLRTIGDETTRLDRNEPALNEAKVGDPRDTTTPAAMLETLGNLAFGPVLAEASRK -LLIEWMVANTTGDLRIRAGLPKAWKVGDKTGTNGNGAASDIAIVWPEGRGPLLIAVYIAE -ATAPLAELNTVFADVGRMAAE-- ->[subseq from] KPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DD3F104 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYXDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSXPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAXPADWAVGDKTGTCGYGXANDYAXVWPTGRAPIVLAVYTRA -PNKDDKYSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. 15K316 TaxID=2530376 RepID=A0A4R4QLR1_9ACTN ---AVDREFGRLETEFGARLGVFAVDTGSGATV-RHRADERFAYASTFKALAAAVLLDRTS ---AAELDEVVRYSRSDLVAHSPVTEQHVATGMRLRDVADAAVRYSDNTAANLMLRRLGGP -DGFERELRRLGDTTTEADRYETALNEGRPGDRRDTSTPRAFATDLRAYTVGDALSREDRD -ILNGWLRGNTTGDALIRAGVPAGWTVGDKTGGGGYGTRNDIAVLRPPAGAPIVLAVMSSR -DAENAPYDDALIARATRIVVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Thauera sp. K11 TaxID=2005884 RepID=A0A290ZUV5_9RHOO ---AVAARLQALEADVGGRLGVYVVDTQSGAGY-GYRPDERFLMLSSFKLLASALVLHRVD -AGLDSLARRISYGREDLVPWSPVTGRHAGGEMTLAGLCEAAVTTSDNTAANLILASYGGP -AALTAYLRQLGDTVTRLDRNEPTLNDKHPHEPFDTTSPRAMVGSMRKLVLGEALSAASRE -RLQQWLLGNTTGGRRLKAGLPADWRIGDKTGTAGM-DANDVGVVWPPGRAPLLVAAYLAD -SPAEGAAREAAIADVGRLL---- ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium phragmitis TaxID=2670329 RepID=A0A2S9IK71_9RHIZ --qNLGSRLAELEGRHGGRIGVAVLNLATGERI-GHRSDERFLMCSTFKALAAAFILARVD -RGEEQLGRRIVYSKKDLVTWSPITENHVGGALSVAELCQATVTLSDNTAANLLLASFGGP -AALTTFLRSIGDEITRLDRTEPELNQDKPGDLRDTTTPAAMLGTLRKLVFGDVLSRPSRA -QLAAWMIMNKTGDAKLRAGFPGNWTVGDKTGGNGFGNSNDIAIAWSPDRGAVIVAAYCEI -PSVSEEERGAVLAEVGRIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB4996 ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWMVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFGEVGRIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces anulatus TaxID=1892 RepID=UPI0013C9410E -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRTFVLGNALAGPERA -RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110611 TaxID=1621259 RepID=A0A1B6ABE5_9ACTN -------EFKKLERKFDARLGVYAIDTGTGREV-AYNDGERFGHHSTFKAFAAGAVLRKHS ---LGGMDKVIKYSSDDLVDNSPITEKHVATGMTLRELCDAAVRYSDNTAANLLFADLGGP -KALNAVLKELGDDVTRMARIEPELSNWVPGEKRDTSTPRALAEDLRAFVLGDALGKAERE -QLTQWLRTNTTGAELIKAGVPKNWVVGDKTGAGSYGARNDIAVVWPPDGAPIVMAILTNR -TTKDAVFDNKLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces globisporus TaxID=1908 RepID=A0A423UYI7_STRGL -------DFKELERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2L1J0V2_PSEAI -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATM------------------ ->[subseq from] Beta-lactamase n=2 Tax=Acinetobacter TaxID=469 RepID=J3S801_ACIBA ----VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. UNC358MFTsu5.1 TaxID=1449049 RepID=UPI0005555552 ------RGIAALEARSHGRLGVSVLDSASGKTF-AYRGDERFAMCSTFKALVAGLILKRVD -QGQERLDRRIPYGREVLLAHSPATEKHVGQGMTVGALCEATVTLSDNAAANLLLMSFGGP -PALTTFVRGLGDKVTRLDEYEPTLNVVRPGEIHDTTSPNAMLATLRALTLGPVLSPASRR -QLVDWLVANQTGDARLRAGLPKGWKVGDKTGSWGVGTTNDIAVVWPPGKPPLLITAYLSR -STLDNDGRNAVIAEVARLVTT-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00094B1415 ---ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALRPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI0007F93709 --eKLNHELTILEKNSGGRLGVALINTENNDLT-LYRADERFAMCSTSKVVAVSALLKKSE -SDKTILGKNIALHEAELVTWSPVTEKNITTGMTLGALSAATLQYSDNTAMNSILNYLGGP -SAVTAFARSIGDEKFRQDRPEPELNTAIPGDERDTSTPLAMATTLQKLTLGDALATPQRK -QLVEWLKGNTTGTASIKAGLPEGWIVGDKTGSGDYGTTNDIAVIWPPEKSPLILVIFFTQ -PLQDAQSRKDILAEATKIVVSPf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Root239 TaxID=1736499 RepID=A0A0Q9HGT1_9BACI ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQSLPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. URHA0033 TaxID=1298862 RepID=UPI000407770B ------RGMAALEARSGGRLGVAVLDTASGKTF-AHRGDERFAMCSTFKALVAGLVLKRVD -QGLERLDRRIVYGRNVLVAHSPVTEKHVDEGMTVGALCEATVTLSDNAAANVLLYTFGGP -PALTAFLRGLGDKVTRLDGYEPGLNIVRPGEIHDTTSPAAMLATLRALTLGPALSPASRQ -QLVAWLVANQTGDKRLRAGLPGGWTVGDKTGSWGAGTTNDIAVIWPAGGPPLLIAAYLSR -STLSDDGRNAVIAEVARLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus ihbetae TaxID=1870820 RepID=UPI000985D929 -------LFKSLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLLQNS ---IEEIDEVISYSAEDLVTYSPITEKHVSTGMTLRDIMDAAIRYSDNTAGNLLLEQLGGP -EGFEAALRQIGDTVTQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPKDKQT -ILTDMLRGNTTGDELIRAAVPEGWAVGDKTGAGSYGTRNDLAIVWPPEGDPVVLAVLSSR -DTQDAEYDNALIAKAAEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000DEF32B7 -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWXVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID6648 TaxID=2706084 RepID=A0A6B3CJG2_9ACTN -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAGDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005C463FB ---ELRYKWAEIERGSGGRLGIGLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDVALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Sediminibacillus terrae TaxID=1562106 RepID=UPI001296E437 ---DLDEAFTEIEEAFDARLGVYAIDTGTNQSV-EYNPDERFAYSSTYKLLAAAFVLKQND ---LQDLEEVVTYSKDDLVTYSPVTEKQVDTGMTLSEISEAAIRESDNTAGNLLLDALGGP -DNYKQALRDIGDDVTQPERYETELNAFSPENKRDTSTPRAMANNLRKVALGDFLPKEKQE -LLIDWMKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVMAIMSRH -KTEGAEYDDELVAKAAEATLNAf ->[subseq from] class A beta-lactamase n=1 Tax=Xenophilus sp. L33 TaxID=1747220 RepID=UPI00131BDF9E ---SLGRAFADIEQMSGGRLGICVLDTGSGLRA-GHRQDERFPLCSTFKLLAAAAVLARVD -KGQLRLDQRIVYGAGDLVAGSPETKLHVGEGMPLAAVCKAAITLSDNTGGNLMLAQIGGP -AGLTRFARTLGDGLTRLDRTETTLNEARPGDPRDTTTPQAMLGDMHRLLLGSALSVGSRQ -QLLEWLEANKTGDKRLRAGLPADWRVGDKTGSGENGTANVIAIVRPPQRAPILVTAYLTA -TTASTDLQNASLAAVGAAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A120EEM8_BACMY -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGEP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDNLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas albilineans TaxID=29447 RepID=UPI0005F30977 ---ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFVLVAAVLQRVD -RGEIGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP -PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLQPASRQ -RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM -ATVDSDARDAALKAVAQAVVAWw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000D1102D2 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKESLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFTLGDILSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis DB27 TaxID=1431339 RepID=W8Z1P0_BACTU ------DSFVKLEKEFDAKLGIYALDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADTSLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGGEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A345N8B5_ACIBA ----VLEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. DMKU_BBB3-04 TaxID=2593654 RepID=A0A553GTZ8_9PSED ---DLEARLIALEGETGGRLGVAVLDASGGLRA-GHRQDERFPLCSTFKVLLAAQVLARCD -QGVEDLERPVRVRADDLLDYAPVTRPAVGRELSVATLCEAAITLSDNTAANLLLARSGGP -AGLTAFLRSLGDKVTRLDRIEPDLNEARPGDPRDTTSPAAMLHSLQRLLLGDALAPASRD -RLEAWMVATRTGDARLRARLPADWRAGDKTGTGARGTYNDVALFRPPQGGPWLVSAYLTG -ASAPAARCEAALAEVGALIA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=Q6ZY54_KLEPN ------EQIKQSESQLPGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTHLDRWETALNEALPGDARDTTTPASMAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLRD -TPASMAERNQHIA---------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZHY6_KLEOX ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGEVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. Q54 TaxID=1335060 RepID=UPI00115A2788 ---TVAETAAEVEADLGGRVGVLLQQYGEAPAA-TYRADERFPLASTFKALACGAALSRVD -AGEQDLEAIIKYGADDIVTYSPITEKHVGVGMTLGDLCHATITLSDNTAGNLVLDSVGGP -SGFTAFMREIGDEVTRLDRWEPELNEALPDDPRDTTTPRAVVTTLERLLLGDVLLPASRR -QLEEWMIADQVADKLIRASLPKGWTIGDKTGAGERGSRSIIAIIRPPQGKPWLAGIYLTG -SDADMDKRNEAVATVGAAIVR-- ->[subseq from] Beta-lactamase n=1 Tax=Mycetocola sp. 622 TaxID=2173166 RepID=A0A2U1TCB2_9MICO -----DGEFGELEQKFDARLGVYALDTGTGLAL-EYRSDERFAYASTIKVFASAVLLDQTS ---DDELDARVTYDESDLLDYAPITEQHVDSGMTLRELGDAAVRYSDNTAANLIFERIGGP -EGLADALTAMGDDVTQVDRTEPELNEATPGDPRDTTTAEAFATTLEALVLGDALEASDRE -LLTEWLVGNTTGDKLIRAGVPADWTVGDKTGSAGYGTRNDVAVIWPTEGDPIVLTVLSSR -SEADADYDDALIAESTAVAIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000A30309B -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSITNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGNNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADASKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000779F760 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMEDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -GKEDAEYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sp. FIM060022 TaxID=1479020 RepID=A0A432N762_9ACTN --------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLRATT ---AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP -AGFKQALRDIGDDVTEPARIETALNAATPGDVRDTSTPRALATSLRAYAVDDALTTEDRD -VLVDWLKRNTTGEKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDREPIVLAVLSSR -DAEDAGTDDALLARAAELTL--- ->[subseq from] Beta-lactamase n=1 Tax=Psychrobacter fozii TaxID=198480 RepID=A0A2V4VSZ5_9GAMM ----ILEAVTNAETELGARIGLAAHDLETGKRW-EHKSNERFPLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter piscinae TaxID=1580596 RepID=A0A291FV89_9RHOB --qDLQNTVADWEERLNARIGVVLRDTSSDWEI-SMRAEERFPMSSTFKSLLCGAVLSRVD -AGQEDLDRRVTYAEGDLVAYSPVTEQHLDNGLTVGELCEATVTLSDNTAGNLLLDTVGGP -EGLTNFLRDIGDQTTRLDRWETALNEAAPGDPRDTSTPSAILNTLETLLLGDVLEPATAA -QLRQWMIDDQVADALIRAHLPEGWVIGDKTGAGGNGSRAIIAFIEPEADVHYFAAIYLTE -SDADFALRNQVVSEIGQAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MNU77 TaxID=1573406 RepID=A0A1Q8U065_9ACTN -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQALLAELGDDVTRMERWETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAGPERA -RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDPDADYDNTLIAKATSAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces olivochromogenes TaxID=1963 RepID=UPI0007497376 -hrDTRARLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPGCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPTTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAADSPLVAATATVLA--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacterales TaxID=91347 RepID=Q48488_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVKYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATM------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus tequilensis TaxID=227866 RepID=A0A2X0X2U6_9BACI -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-SYRPHERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLDGP -KGFEKSLKQIGDHVTRANRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTIDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKTVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. 60-20 TaxID=1895819 RepID=A0A1M3PR76_9RHIZ ---DVDKQLADLEKRTGGRLGVSVLDTETNISL-GHREEERFPLCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDKVVTYSPATEKHADADMTIAELCGAAITLSDNTAGNLLLDSFGGP -AALTSWLRTTGDTETRLDRNEPDVNQAVKDDPRDTTTPDAILDTIGLLTLGNTLSETSRD -QFVNWLVANTTGNNRLRAGLPNEWKVGDKTGTGNNGSYADIAVIWPPERGAILVTTFVAE -ATAPAKDVESVFAEVSKIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0011B7D079 -----DGEFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. STM 3809 TaxID=551936 RepID=H0T420_9BRAD ---DLQATIAGIETDSGGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILAKVD -AGAEQLSRRLPITQADILAYAPVTKLHVSTSLAIGELCEAAVTLSDNTAANLLLATLDGP -AGLTRAIRGFGDAITRLDRIEPALNESVPDDPRDTTTPAAMARTLAKLTTGNALSASSRD -VLNGWLLGCKTGAAKLRAGLPASWRVGDKTGSGERGSSNDVAVIWPAGRAPVIVTSYLTE -TKASDDKRNAAHAAVGRAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces anulatus TaxID=1892 RepID=UPI0013BDDE91 -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERWETELNEWTPGATRDTSTPRALTEDLRAFVLGDALAGPERA -RLTQWLTANTTGGELIRAGVPKGWTVGDKTGAGRYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E0DDC30 ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPKDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F931_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDECDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIVALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. kraussei Becker Underwood TaxID=1398204 RepID=A0A077PTY1_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMAVSALLKKSE -TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLGQLGGA -HSVTRFARSIGDNTFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRA -YLVEWLKGNTTGGTSIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ -PSKDAKAHNDVLAAAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. C22 TaxID=2580567 RepID=UPI0011A1396C ----ITAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP -GAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ -QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE -TDATFEARNEAIASLGEVVQ--- ->[subseq from] Beta-lactamase n=1 Tax=Azoarcus sp. DD4 TaxID=2027405 RepID=A0A4Y6KQG6_9RHOO ---QLAELCRKLEADSFGRLGMYLFDGRSGQEF-LYRSEERFPMCSTFKWLAAAAVLARVD -AGKERLDRRIRFAGQDLLEYSPVTRSFADGPMSVAQLCEAAVADSDNTAANLLLDALGGL -EAFNAFLRAQGDSLTRLDRYEPDLNEARPGDPRDTTTPAAMGADLRRLLLGDGLGSHSRQ -QLTDWMLATRTSGERLRAGLEAGWRLADKTGTGDNGTANDVGVYWTPTGQPVVLCVFLTG -ARTDRAAQAAVMASLGRQV---- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A7C568_BACCE -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITKKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKKDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD57882 ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWLVANTTGNERLRTGLPEAWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVTTAEINPVFGEVGRIVAE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0009BE7069 --qATHKEFSQLEKKFDARLGVYAIDTGTHQTI-AYRPNERFAFASTYKALAAGVLLQQNS ---TDKLNEVITYTKDDLVEYSPVTEKHVDTGMTLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVCPQNRAPIIIAILSSK -DEKEATYDNQLIAEATEVIVK-- ->[subseq from] Beta-lactamase n=3 Tax=Xanthomonas vasicola TaxID=56459 RepID=A0A2P5ZK72_XANVA ---MLRAQWAKIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD -QGKLMLAQRVKIRASDMLEHAPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRSIGDAQTCSDRHEPEMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK -QLTDWMINNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG -AKVDDAARDAALKAVAVAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E325B6C ---MLRARWAEIQRGTGGRLGTCLLDSGTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRIEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLAAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4J428_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMA----------------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2E6_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0R7FFW3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -ES--------------------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0009B1B99E --qATHKEFSKLEQKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRYSDNTAGNILFHKIGGP -KGCGGGLRKMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIARNLKDFTIGNALPHQKRN -ILTDWMKGNATGDKLIRAGVPTDWVVADKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEKEATYDNQLIKEAAEVVID-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T131_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEALSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0V2_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEALSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. FJAT-21352 TaxID=1581030 RepID=A0A5E8LAC3_9BACI ----TIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGNPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. MSP13 TaxID=1071061 RepID=UPI0009E20162 -----NEKFVQLEKKFDAKLGVYAINTGTNKTI-SYRPNERFAYASTYKVLAAAAVLKKNA ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNNLTPDKRT -ILTDWMRGNATGDELIRAGAPIGWLVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR -FTEDAHYDNALIAEAAKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000B8297AD ----TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGKEEIISNSPVTEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGIGDQVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYALGSALPAEKRA -VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPDAAPIALAVLSRR -DTEDAEPDDALIAGAAKVALGAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID8374 TaxID=2690354 RepID=UPI0013684D21 ----TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGKEEIISNSPVTEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGIGDQVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYALGSALPAEKRA -VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPDAAPIALAVLSRR -DTEDAEPDDALIAGAAKVALGAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. SPB7 TaxID=2715209 RepID=UPI0014201ADF -----SKKFVQLEKKFDARLGVYAIDTGTNKTI-TYRPNERFAYASTYKVLAAAAVLKKNP ---IDKLNEVIHYSKDDLVTYSPITEKHVDKGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFIVDNTLTSDKRT -ILTGWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDASYDNALIAEAAKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora maris TaxID=1003110 RepID=UPI0005BCF2E2 --------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLKATT ---AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP -AGFKQALRDIGDDVTEPARIETALNAATPGDVRDTSTPRALATSLRAYAVDDALPTEDRD -VLVDWLKRNTTGEKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDREPIVLAVLSSR -DAEDAGTDDALLARAAELTL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PgraA7 TaxID=1157641 RepID=A0A212RVT0_9ACTN -------DFKKLERAFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWTVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI00052D5C41 ---MLRAQWAQIEHGTGGRLGICLLDSATGKRL-GQREHERSPMCSTFKFVLAAAVLQQVD -QGKLTLAQQVEIHASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFVAGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTAGWKIGDKTGSNGTDTRNDIAILWPPKGAPMLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. cf386 TaxID=1761904 RepID=A0A1H0N9F8_9ACTN ---DVTARLRALEQQHGARLGVFAHNLATKRTV-RHRADERFPICSLFKTLAAAAVLRDLD -RDGEVLNKRIHYTAADVVANSTVTEKHVATGMTVAELADAAIRFSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRATDTTSPRAIGRTYARLVLGNALNRPDRD -LLTHWLLNNTTSVNRFRAGLPRTWSIADKTGGGSYGTNNDAGIAWTEDGTPLVLVVQTTR -PDQDAAPDHALIVETAELLAD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=H1AFJ1_ENTAS ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVRELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVILSCG -IRASMAERNQQIA---------- ->[subseq from] Beta-lactamase class A n=1 Tax=Pleomorphomonas sp. CF100 TaxID=2135722 RepID=A0A4R8F802_9RHIZ --------FAQLEKERGGRLGVAALDKTTGSRI-GYRADERFAMCSTFKCLAAAAALARVD -KGELKLDKVISFGKADLLSYAPVTKQHVDKGMTLEELCAAAVSVSDNTAANLILKEIGGP -AGWTAYARSLGDKVSRLDRTEPALNTAVAGDVRDTTSPNAMLGNLDKLFIGDILSETSRD -KLEEWMVTGTVTGPLIRAGVPKNWQVADKSGSGANATRNDIGVLYRPEKAPIIAAIYYTG -SKLDMDGQNKVIADAAALIASRf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A8HNS6_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAP--------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XJX6_9ACTN ---AAEQEFQRLEKTFQARLGIYAVDTGTGRTV-EHRPDERFAYASTWKALAAAEVLDGTT ---DAELDRVVRYSAQDLVSHAPITEKHVAEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -QGFEKKLRGIGDTVTDPARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD -VLLGWLKGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVVAVLSSR -DKLDATPDDALIAQATTVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL6665CI2N2 TaxID=1938806 RepID=A0A4R8JTS0_9BURK ---AIRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLVAGAVLARTD -RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNTAANLLLATFGGP -AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDIAILWPSGRGPVLVTVYLTE -TDGNAARSNAAIADVGALVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia araoensis TaxID=228600 RepID=UPI000307F065 ------AGVADLEARYGAQIGLFALDTGTGRTV-THRADERFPFLSTFKTLAVAAVLRAHP -LDTGYFDQVLRFHEADLVDNSPVTSAEVAGGMTLARVAEAAITRSDNTAGNLLLREIGGP -EGLTAFLRTLGDPTSRLDRWETDLNTAIPGDERDTTTAAALAADYRALALGDALGARERD -QLVAWLKANTTGGKRIRAGLPADWVTGDKTGTGSYGSANDVAIVWPEGGAPIVIAILSRK -PAADAEVNNDLLAEVTKVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. 2FB TaxID=2502187 RepID=UPI0010F4E572 ----LQDSLRDIEKQAKGRLGVHIIDTASGREL-GWRGDERFLMLSSFKLLASALVLDRAD -RGEASLEQRIRYRKQDLVSWSPVTERHVGGELSLAQLCEATITTSDNTAANLILASYGGP -AALTAYARRLGDRATRLDRTEPELNRAASGEPLDTTTPRAMAHTLNKLLLGDALKPASRE -RLTQWLRANTTGGKRLRAGVPSGWQIGEKTGTAGD-DANDIGIAFPPQRKPIIVTAYLAE -SVTDSGTREAALASVGRLLAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1EB0BB ---ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATIDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Nevskia ramosa TaxID=64002 RepID=UPI0003B2F4D0 ----LQARCKALEAKLGGRLGMNCLEVGSGRMV-GYKADERFPMCSSFKWLAAAVVLSRVD -AGQEQLGRRIQFSRDELMEWSPVTEPRLGGDMTLGELCEAAITESDNTAANLILRETGGI -PEWNRYMRSIGDAYSRLDRGEPLLNEALPGDVRDTSTPAAMTANLRRLLLEDQLSPASRE -QLTQWMLATKTSDKRLRAGLPAGWRLADKTGTGDTGTAGDVGVLWSPSGKPIIIAVYLTR -ARVSRAEQEAAIAEIGRWVR--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=H9AXM5_XANCE ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALHPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E1F9825 ----LRAQWAEIERGTGGRLGISLLDSATGWRI-GQRENERFPMCSTFKFVLAAAVLQQVD -RGKLPLAQPVKIGASDMLSHAPVTERHVGGALSVGELCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLGTLLLGNALQPASRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAGRDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A2A2DEQ2_9ACTN ---EAERAFGELERTYDARLGVYAVDTGSGRVV-AHRPDERFAYASVCKAFLAGAVLKKNT ---LQGLDRHVRYGREVPVGHSPVTGRHVGSGMTLRELCDAAVRYSDNGAANLLFDELGGP -KGLQEALAAIGDRVTRADRYETDLSEAAPGDPRDTSTPRAMAADLRAFVLGDALAPDERS -ALTDWLKRNNTGDKLIRAGVPAGWQVGDKTGSGGYGARNDIAVLWPPRAAPIVVAVFSSR -TAKDAKADDTLIAKATEVTVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4IQA0_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TP--------------------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVW4_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGELLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110027 TaxID=1546107 RepID=A0A0P4RF40_9ACTN ----SAQAFKELERKFDARLGVYAINTSTGREI-TYHQDERFAHASTFKALAAGAVLRKYS ---LPGMDKVITYSRDDLVSNSPITEKHVDTGMTLRALCDAAVRYSDNTAANLLLDSIGGP -KGLDAALEKLGDHTTRMVRHEPELNDWAPNDTRDTTTPRAFAKDLRTFVLGDTLPRRERA -QLAKWLQTNTTGAKLIKAGMPKTWLVGDKTGAGSYGTRNDIAVVWPPHAAPIVVAIMSNR -TQKDAKYDDALVAGAASVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. IC_126 TaxID=2547400 RepID=A0A4R0PSG2_9PSED ------RKVMELETRLGARIGAVVRSSHADMHW-AYRADERFPMCSTFKLLASGSLLAQVD -AGREQLDRIVRFEIADVVDYSPITESQAGGDMTLAQLCEAALTHSDNTAGNLILEQIGGP -GGVTEFAWSLGDTVTRLDRWETELNEATPGDPRDTTTPAAMAQCVDVMLFGDALSASSQQ -QLSDWLVANKTGDAKLRAGMPASWRIGDKTGGGDHGTMNDVAVIWPPQQHPLIVSIYMTE -TVASFDDRNAAFAELGRTLYELf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium (strain DSM 319) TaxID=592022 RepID=D5DH82_BACMD ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLDGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A1136 TaxID=2563102 RepID=A0A4S2ST97_9ACTN ---SAADAFAALERGHDARLGVYAVDTGTGRTV-AHRADERFAYASTYKALAAGAVLRKNT ---LEGLEKVVHYTHGDLVTYSPVTEQHVDTGMTLRALCDAAIRYSDNTAGNLLLDALGGP -KGFQAALVALGDGTTQVDRYETALNEATPGDPRDTSTPRTLAADLRAYTLGDALNAEKRA -LLTGWLGRNTTGDELIRAGVPAGWWVGDKTGSADYGTRNDIAVVRPPEAAPIILAILSTH -ASRDTTPDNELIAQATRDVI--- ->[subseq from] Beta-lactamase n=2 Tax=Baia soyae TaxID=1544746 RepID=A0A4R2S3T1_9BACL ----VNQTFTDLEKKFDARLGVYAIDTGTGRSV-THRSDERFAYASTFKTLIVGMLLKQKS ---VDQLNELITYTKEDVTRYAPITEKHIDTGMTLKELCDATLRYSDNAALNLILEKIGGP -TVARKELMRIGDYTTKPFRFEPELNEATPGDIRDTSTPKALATSLKAFTLGNVLQADKRD -MLIDWMKRNTTGDKLIRAGVPAGWVVGDKTGSGGYGTRNDIAIVWPPNRAPIVIAVLSSR -DKKDATYNEELIAQATKEVIR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T1Q6_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEVLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSIVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. SYP-A9097 TaxID=2663237 RepID=UPI00129B5CDA ------QPFADLETKAGGRLGVYAIDTATGKTV-TYRDGERFPIASTFKGLACGALLRGHP -LSSGYFDQVIHYPASDLVTYSPETEKHVDSGMTVTELCRAAITLSDNTAGNQLLKLLGGP -EGLTAVIRTLGDPITRLDRWETELNTAIPGDERDTTTPASLAADYRALVVGDALAEPERA -QLKSWLLANTTGGKRVRAALPADWTIADKTGSGDYGSASDAAIVWPPNHAPIVIVVQTTK -PDPHAEGDNALIADATRLAIQ-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas phaseoli pv. syngonii LMG 9055 TaxID=1437878 RepID=A0A1V9HI73_9XANT ---MLRAQWAQIERGTGGRLGICLLDSATGKRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQQVRIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRGIGDAQTRTDRYEPQMNRFAAGGPRDTTTPAAIAVTLRTLLLGDALQPASRK -QLTRWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAFAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000D03F1CF -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucosispora maris (strain AB-18-032) TaxID=263358 RepID=F4F8K0_VERMA --------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLKATT ---AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP -AGFKQALRDIGDDVTEPARIETALNAATPGDVRDTSTPRALATSLRAYAVDDALPTEDRD -VLVDWLKRNTTGEKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDREPIVLAVLSSR -DAEDAGTDDALLARAAELTL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. cf386 TaxID=1761904 RepID=UPI000B859647 ---DVTARLRALEQQHGARLGVFAHNLATKRTV-RHRADERFPICSLFKTLAAAAVLRDLD -RDGEVLNKRIHYTAADVVANSTVTEKHVATGMTVAELADAAIRFSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRATDTTSPRAIGRTYARLVLGNALNRPDRD -LLTHWLLNNTTSVNRFRAGLPRTWSIADKTGGGSYGTNNDAGIAWTEDGTPLVLVVQTTR -PDQDAAPDHALIVETAELLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E209619 -----DREFAKLEEKYDAHLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQTYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYGTRNDIAILWPPKGDPIVLAILSDR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00072 TaxID=1703928 RepID=A0A1Q5A771_9ACTN -------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAKPERA -RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A1D7VMH9_9ACTN -------DFRELERKYGARLGVYAVNTGDGREV-AFNADERFAYASTFKAFAAAAVLRKYS ---LSGMDKVIKYSRSDLIDHSPITEKHVDTGMTLRDLCDAAVRYSDNTAANLLFDALGGP -QGLAAALAKTGDTTTKVERREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE -QLTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR -GTKDADYDNKLIAEAASLVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A2W5PQW6_VARPD -----AAALARLEEGLSGRLGVFAIDTATGATI-GHRASERFPICSTFKAVLAGALLARGV -REPGLLDERVRYTKADLIAHSPITGRELARGMTVAELCAATVQYSDNAAANLLLRRIGGP -EALTAQARAWGDSTFRLDRWETELNSALADDPRDTSTPEAMARLLRTLAVDDGLPTAQRA -RLQDWLRGNTTGGARVRAGMPAAWTVGDKTGTGAHGAASDIAVVWRPQAAPLVLAVYTRL -EAQDAKPRDDVIAAASRIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5P8_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLRLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSVLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIHTTG -SQATMDERNRQIAE--------- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BFD0469 ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEATPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPNDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI0011A88403 --tQAERELAALEHDFAGRIGVCAIDTADGALL-GQRADERFPMCSSFKAVLAAAILARSG -AEPGLLAQHVRYQRGDLLPHSPVTSQHLAEGMSVAGLCEATVQTSDNAAANLLLQRVGGP -AGLTAFMRSIGDAQFRLDRWELELNSSLPGDPRDTTTPRAMAESLRKLAVDDALAPPHRA -QLATWLRGTVTGAARIRAGMPAGWVVGNKTGTSGYGSAIDVAVVWPPARAPLVLAVFTTR -HAADAPALDAPIAQAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. S3-2 TaxID=1747903 RepID=A0A1A7C0X4_9BURK ---DAQAQLAALEQAAGGRLGVSALHTGSGARI-SHRADERFPMCSTFKSMLAAAVLARST -SEPQLMNQLVRYEAKELVTYSPVTEKHVATGMRVAELCAATLQTSDNSAANFLMKILGGP -QAVTAYARSIGNEVFQLERWETELNSAIPGEVRDTTSPEATVKSLYGLLLGTSLPAAQRQ -QLDTWMRGNTTGDKRIRAGVPAGWKVADKTGSGAYGSVNDIGVAYPSGDAPLVIAIYYTR -EQKDAPINQDIITAATRIVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BF9C6F5 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKNVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK11 TaxID=1628212 RepID=A0A0J6NKI0_9NEIS -----ARQLAELERNAGGRIGVFAQEVDSGRSL-AYRADERFPMCSTFKLLLVGALLQRSV -AQPDLLYRHVDYRRDQLIDYSPISEQHVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP -QEVTRFARSLGDGQSRLDRIEPELNLAEPDDPRDTTTPAAMTANLHALLFSPLLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVYYWG -SSAMMDERNAVIAAVARVAAAEf ->[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. 1H6 TaxID=1911585 RepID=UPI0009C98047 ----VDTRLAELEKCTGGRLGVSVLDMETNVSF-GRRESERFAMCSSFKTLAAGFALARAD -QGAEKLDRRIVVAQKDIVAHSPVTEKHVGGEMTIAELCAATLTTSDNAAANLLLENFGGP -PALTAWLRTIGDETTRLDRNEPALNEAKVGDPRDTTTPAAMLETLGNLAFGPVLAEASRK -LLIEWMVANTTGDLRIRAGLPKAWKVGDKTGTNGNGAASDIAIVWPEGRGPLLIAVYIAE -ATAPLAELNTVFADVGRMAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD7D342 ---EIDRRIGALEKQIGGRIGVSAIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAGNLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWMVGNTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFGEVGRIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=UPI0009A20113 ----IRQKLAELEKQSGGRLGVMAIDNASSDRV-GYRETERFPFCSTFKIVLVGAILNRSL -ENGSLLQRRVRYGAGELVAYSPVTEKAVGAGMTVSGLCAAALQYSDNTAGNLLIRELGGI -AAVNEYARKIGDQGFRLDRMETELNSAVPGDERDTTTPLAMAQTLQGLTLGETLPELQRR -MLVDWMRGNTTGGTRIRSAMPRDWQIGDKTGGGDYGTTNDVAVIWPGSESPVVLAIYFTQ -TAKDAPMRNDVVAEAARIVGEHf ->[subseq from] Beta-lactamase Ohio-1 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=BLA1_ENTCL ------EQIKLSESQLSGSVGMIEMDLARPGTLtAWRADERFPMMSTFKVVLCGAGLARVD -AGDEQLERKIHYRRQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLPAVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTARSMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGRLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIAGALIEHw ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus megaterium TaxID=1404 RepID=A0A6B3RB43_BACME ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDQIVLAILSNR -AEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC05858 TaxID=2487409 RepID=A0A3R9U7Q4_9ACTN ------GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLAALCDAAVRYSDNTAANLLFDQLGGP -KGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAEDLRAFVLGDVLGDGERA -QLTKWLRTNTTGDALIRAGVPKNWQVGDKTGTGSYGGRNDIAVVWPPDSAPIVMAIMSNR -GDKDATSDDKLIADAAHVVADQ- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. TSRI0369 TaxID=1703936 RepID=A0A1Q5HEE8_9ACTN ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAVLAATS ---DADRDRVLRYRRADLVAHSPVTERHVDTGITLRDAAEAAVRHSDNTAGNLLFDALGGP -AGFARALRDAGDRVTRPVRTEPELNAATPGDTRDTSTPRALVGSLRAYTLGDALPPADRD -LLLGWMRASTTGSALVRAGTPAGWQVADKSGTGGYGTRNDIAVVWPPDGAPIVLAVLTSH -DSRDAKPDDALVAQAARATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI000A04569F ----ANTSVADLEARYGAQIGLFAVDTGTGRTV-THRADERFPFLSTFKTLAAAALLRSHP -LDTGYFDRVIRFHEADLVEYSPVTSAGVAEGMTLARVAEAAITRSDNTAGNLLLRELGGP -EGLTAFLRTLGDPASRLDRWETELNTAIPGDERDTTTPAALAADYRAAALGDALGAPERD -QLVAWLKANTTGGKRIRAGLPANWVTGDKTGTGSYGSANDVAIVWPEGGAPMVIAILSRK -SDADAEANNDLLAEVTKVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WMMB 714 TaxID=1286822 RepID=A0A1C6PQA9_9ACTN --kQAARELRKLEEKFGARLGVYAVDTGSGEEV-AYKDRERFAYASTFKALAAGAVLRKYG ---PDRMDRVIEYSRDDLVDYSPVTEKHVGTGMSLRALCDAAVRHSDNTAANLLFDALGGP -KGLDAALERLGDDVTRMERREPELSRWKPGSTPDTSTPRAIAGDLRAYVLGDALRKPERS -QLAEWLRRNTTGDGLIRAGVPEGWKVGDKTGTGGYGVRNDIAVVWPPRAAPVVMAIMSNR -SGEDAEPEDELIAEAASAVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis gilva YIM 90087 TaxID=1235441 RepID=A0A223SAI8_9ACTN ---SFEQEFKQLEKEFDARLGVYAIDTGTDEAV-SYRADERFAYASTHKAFSAGAVLQQTP ---LEELDDIVTYAEDDLVSHSPITEKHVDTGMPLRDVVDAAIRYSDNTAANLLFRELGGP -KGLGEALKEMGDETTHVDRVETELNEAAPGDIRDTSTPEAMATTLRKFTLGDTLPADKRE -ILTDMLKGNTTGDNLIRAGVPDDWTIGDRTGGGGYGTRNAIAVAWRPNGDPVVFAIMSSR -DDKDAEWNDKLVAEATEIAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CF097 TaxID=1500301 RepID=UPI00055FB720 --nDIAQQLASLEERTGGRLGVSVLDTNTNVSF-GHRQDERFAMCSTFKALAAAFVLARVD -KGEENLDRRIAVSNADLLSHSPIAEKHLADGMTVGELCGAAVTYSDNAAANLLLASFGGP -VGLTAWLRSIGDETTRLDRTEPALNEAKLGDPRDTTTPVAMMRTLGRLLLEDVLSPPSRD -RFAAWLVANTTGGRRLRAGLPGGWTVGEKTGTNGKGAAGDIGFMRPREGHTILASVYIAE -AMKPVKELEPIFAEVGKLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000A365992 ------DSFVKLEKEYNAKLGIYALDTGTNQTV-AYHPNDRFAFASTSKSLAAGALLRQNS ---IEALDERITYTREDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTGKRE -LLVDWMKRNTTGDKLIRAGVSKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADATKVVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Thermoactinomyces sp. DSM 45891 TaxID=1761907 RepID=A0A1K1VDT9_9BACL ---DVNQAFTDLEKKFEARLGVYAIDTGTGRTV-THRSDERFAYASTFKTLIVGMLLKQKS ---VDQLNELITYTKEDVTRYAPITEKHIDTGMTLRELCDATLRYSDNAALNLILEEIGGP -KVARQELMRIGDHTTKPSRFEPDLNEATPGDIRDTSTPKALATSLKAFTLENVLPMEKRN -MLIDWMKRNTTGDKLIRAGVPDGWIVGDKTGSGGYGTRNDIAIVWPPNRAPIVIAMLSSR -GEKDATYNEELIAQATKEVVH-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum robiniae TaxID=2014887 RepID=A0A246WWD7_9BURK ----IRQKLAELEKQSGGRLGVMAIDNASSDRV-GYRETERFPFCSTFKIVLVGAILNRSL -EDGSLLQRRVRYGAGELVAYSPVTEKAVGAGMTVSGLCAAALQYSDNTAGNLLIRELGGI -AAVNEYARKIGDQGFRLDRMETELNSAVPGDERDTTTPLAMAQTLQGLTLGETLPELQRR -MLVDWMRGNTTGGTRIRSAMPRDWQIGDKTGGGDYGTTNDVAVIWPGSESPVVLAIYFTQ -TAKDAPMRNDVVAEAARIVGEHf ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sinuspersici TaxID=501010 RepID=A0A1V3BZI0_9ACTN ----LAREFERLEKEFDARLGVYAVDTGTEEEV-VHRPDERFAYCSTHKAFSAGAVLQRNT ---PEEMEEVITYTEDDLLDYAPITEQHVDTGMTLMELTDAAVRYSDNTAANLLFEELDGP -DGFEEAMEAVGDDVIEADRVEPGLNEAVPGDIRDTSTPRAMAESLRKFTLGDALPEDRRD -VLTDMLVNNMTGDELIRAGVPEGWEVGDKTGSGGYGTRNDIAVLWPPEGEPIVLAVMSSR -DEEDAEYDNALIAEAAEVVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=I6VDW2_KLEPN ------EQIKQSESQLSGRVGMIGMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPA-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI000BA62BB9 ----TIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDTLPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKDADYNDELIADATEEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=A0A3N9XHJ8_9ACTN ---AADQEFRRLEEQFGARLGVYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTEAARYETSLNEGTPGDKRDTSTARALVGDLRAYTVGVALEPTDRD -VLRGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DKKDATPDDALIAQATRVVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Actinomadura hallensis TaxID=337895 RepID=A0A543IAB4_9ACTN ---EVTERISRLEKTRGLRIGAYAVDTGTGRRV-GHRADERFPFASTFKAMACGAVLRRAD -SDPGLLDRVVRYGKGDLLAHSPVTEKHVKTGMTVADLCRATVTTSDNTAGNLILKEIGGP -AGLTGFLRSLGDRVTRADRWEPGLNDWRPGEERDTTAPRPWADDLRALTVGDALAPEDRE -RLTGWLKATVTGEGRIRAGLPDGWTAGDKTGTGGYGSANDIAVVWPPSGAPLVIAILTTG -RDADAEPDERAIAETTAVLVD-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase Sme-2 n=3 Tax=Serratia marcescens TaxID=615 RepID=Q9F7U6_SERMA ---AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKEKA -IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR -KSKDDKHSDKTIAEASRIAIQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru87 TaxID=2044307 RepID=A0A2B8AMJ1_9ACTN -----ARELKDLERKFDARLGVYAIDTGTGREV-VHNDGERFPYASTFKALAAGAVLHKHT ---PDGMEKVIEYSEDELVHHAPVTEKHVGSGMTLRELCDAAVRFSDNTAANLLLKELGGP -DKLEAVLREAGDDVTRMDRYEPELSRWSPGSTLDTSTPRAMARNLRAFVLGDVLGKDDRD -QLTTWLRTNTTGDELIRAGMPEGWVVGDKTGSGGYGARNDIAVVWPPDSDPIVMAVMSNR -AEKDDAYDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNZ289 TaxID=2572907 RepID=A0A559TY19_9ACTN ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ARELDKVVTYSADDLVAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAEDLRALVLDDALDKRDRA -RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Soil531 TaxID=1736389 RepID=A0A0Q9V8V2_9BACI ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLEQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTARALATSLQKYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces filamentosus TaxID=67294 RepID=UPI00123871E0 ---RAEARFRALEERYTARLGVHAYDVRTGRTL-AHRDRERFPMCSVFKTLAVAAVLRDLD -HDGGFLARRVHYTAADVERWSPVTEDNIARGMTVAELCDATLRFSDNTAANLLLRDLGGP -TAVTRFARSAGDPVTRLDRWEPELNSAEPWRITDTTTPRAIARTYGRLLLGRVLDPADRA -LLTDWMLRNTTSDARFRKGLPADWTVADKTGGGDYGGNNDVGVTWPPDGGPILLAVLTTR -PDRDAEGVDELVAAAAAIAADE- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces noursei TaxID=1971 RepID=A0A2N8PI94_STRNR -----AAELRELERRYAARLGVYARNARTRQVV-AHRAQERFAMCSTFKTVAAAAVLRDHA --HCAPLDKVIHYPARDILPYSPKTQEHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQLGGP -EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDLRDTTTPEAIGTSYGRLALGRVLTHDARE -QLVTWLKGNTTSEHRFRAGLPQHWVVGDKTGTGDYASANDVGVAWTGRSTPIVLAVLSTK -SAKDAPVDEALIADAARIVAR-- ->[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2Q9_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPINQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMASSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. st140 TaxID=1828052 RepID=UPI000BEF3835 -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CP22 TaxID=2580517 RepID=UPI0012BBF1F3 -------DFAPLEREFDARLGVYAVDTGTGHTV-THRADERFAYASTFKALAAAAVLAATP ---TEELDRVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLDRLGGP -DGFKQVLRDLGDEVTEPARWETDLNAYVPGDDRDTSTPRALATTLRAYAVDDALSAQDRA -VLVDWLKRNTTGDTTIRAGTPDGWEVGDKTGTAAHGTRNDIAVVWPPERAPIVLAVLSSR -DRPDADSDDSLLARAAELTLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces antibioticus TaxID=1890 RepID=A0A0L8PLE0_STRAT -----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDQA --DCAPMDRVVHYPPHDILPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFYRSLGDEVSRLDRWEPELNTAIPGDPRDTTTPEAIAASLERVTLGRALARADRE -RFVGWLKGNTTSSARFRKGLPREWVVADKTGTGDYATANDIGVAWTTRRTPLVLVVLSSR -TTPDAPVDEALIADAAAVVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain ORS 278) TaxID=114615 RepID=A4YV89_BRASO ---DFQETIAGIEADSAGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILTKVD -AGAEQLSRRLPITQGDILSYAPVTKLHVGTSLSIGELCEATVTLSDNTAANLLLATLDGP -AGLTRATRGFGDAITRLDRIEPALNESVPDDPRDTTTPAAMAQTLAKLTTGNALSTSSRD -VLNGWLIGCKTGAARLRAGLPASWRVGDKTGSGENGSSNDVAVIWPAGRAPVIVTSYLTE -TKASDEKRNAAHAAVGRAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004BD31E7 -----TARLRELEQEHTARLGVYARNMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD -RDGEFLARRVYFTQDDVDKYSEVTKHHVATGMTIGELCDATIRFSDNTAGNLLLEELGGP -TAVTRFCRSIGDPVTRLDRWEPELNSAEPWRVTDTTSPRAIGTTYARLVLGTALEPRDRG -RLTDWLLGNTTSVERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPGGTPIVLSVLTTQ -PEEDAPADNALVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas meridiana TaxID=29570 RepID=UPI001320291C ---RIAAELERIEQTLDARIGFAAHNIATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALETEVSFEASELVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP -EAITAFVRSMDDPVTRLDRYETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ -QLEAWMMGNAVADGLFRAAMPFDWIIADRTGAGGYGSRSITAIIWPPEQAPTVVVLYITE -TEASFEERNAAIASLGEVVQ--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ms115 TaxID=1827928 RepID=UPI000BF005D7 -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YR528 TaxID=1500258 RepID=UPI000645C1EF ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPETEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNITLGSVLSEPSQK -TLIEWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFGEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A1S2C287_9BACI ----SDREFAKLEDKYDANLGVFALDTGTNKTI-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDNVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPAEKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAVLWPPNGDPIVLAILSDR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sp. ts21 TaxID=2069341 RepID=A0A2N7T873_9ACTN --------FGPLEQEFDARLGVYAVDTGTGRTI-EHRADERFAYASTFKALAAAAVLKATT ---AEELDQVVRYSRDDLVTYSPITEQHVATGMTLRAIADAAVRYSDNTAGNLLFDRLGGP -AGFKQALRDIGDDVTEPARIETALNEGTPGDVRDTSTPRALATSLRAYAVDDALTTEDRD -MLVDWLKRNTTGDKVIRAGTPDGWVVGDKTGSGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DAEDAGTDDALLARAAEL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI000A363504 ------GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLAALCDAAVRYSDNTAANLLFDQLGGP -KGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAEDLRAFVLGDVLGNGERA -QLTKWLRTNTTGDALIRAGVPKNWQVGDKTGTGSYGGRNDIAVVWPPDSAPIVMAIMSNR -GDKDATSDDKLIADAAHVVADQ- ->[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora sp. CWR15 TaxID=2499994 RepID=UPI00140DC5CC ------VDFAPLEREFDARLGVYAIDTGSGSTV-AHRAEERFAYASTFKALAAGAVLAATS ---DEELDRVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP -SGFRQALREVGDEVTEPVRWETELNAYVPGERRDTSTPRALATTLRAYAVDEALSPADRA -VLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPERAPIVLAVLSDR -TEPDAERDDALLARAAELTLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 769 TaxID=1262452 RepID=A0A0A8EYY4_9ACTN -----AAELRDLERRYAARLGVYARNARTGQVV-AHRAQERFAMCSTFKAVAAAAVLRDHA --HCAPLDKVIHYPARDILPHSPKTQEHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQLGGP -EGLTRFFRSIGDPTSRLDRWEPDLNTAVPGDLRDTTTPEAIGTSYGRLALGRALTHDARE -QLVTWLKGNTTSEHRFRAGLPQHWAVGDKTGTGDYASAHDVGVAWTGRSTPIVVAVLSTK -SAKDAPVDEALIADAARIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=A0A1H5B2L8_STRMJ ------GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDAMLEKMGDDVIRMERLEPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGNGERA -QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVMAIMSNR -GDKDATSDDKLIADAAHVVADQ- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A8Q898_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNPIVLAILSNH -DKEDAEYDDILIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain ORS 278) TaxID=114615 RepID=UPI000319B68B ---DFQETIAGIEADSAGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILTKVD -AGAEQLSRRLPITQGDILSYAPVTKLHVGTSLSIGELCEATVTLSDNTAANLLLATLDGP -AGLTRATRGFGDAITRLDRIEPALNESVPDDPRDTTTPAAMAQTLAKLTTGNALSTSSRD -VLNGWLIGCKTGAARLRAGLPASWRVGDKTGSGENGSSNDVAVIWPAGRAPVIVTSYLTE -TKASDEKRNAAHAAVGRAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Rummeliibacillus stabekisii TaxID=241244 RepID=A0A511C0F3_9BACL -----TEAFKKLESEFDARLGVYAIDTKTKKSI-SYQSDERFAFASTYKALATGAMLKQKS ---MKDLDKIITYTKEDLVTYSPITEKYVDTGMTVKDIATAAIRYSDNTAGNLLFNELGGP -NGFEKALRKMGDKVTQSNRLEPELNLTTPGDLRDTSTPRALASNLQKFVIGDVLPTKKKA -LLTDLLVGNATGDTLIRAGVPKDWVVADKSGAGGYGTRNDIAVVWPPDRKPIVIAILSSR -NTKDATYDDALIAKAAKVVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. ABRD_28 TaxID=2268461 RepID=A0A3G6ZI46_9MICO ----LGAELGALEATYDARVGVYALDTETGQTV-AHRADERFAYASTFKALLAGVVLHEID -----DLDRVVTYNSEALVSYSPVTEQYVATGLSIGELAEAAVRTSDNTAANLLLDQLGGP -EGFAAALARSGDEITQPERREPELNSAVPGDPRDTSTPRALVETLRQYALGDLLADAEKQ -TLIDWMSGNRTGDTLIRAGAPEGWTVADKSGTGGHGTRNDIGLVWPPDGEPIVIAVLTTR -GVGDAATDDALVAEAAAVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. BA0156 TaxID=2716225 RepID=UPI00140805C1 ----LAAALRAIESRAQGRLGVHVIDSGSGREW-GHRSDERFMMLSSFKTLAAALVLARAD -QGLAPLAQRVRYGRAELVSWSPVTERHVGGELTLAELCEATITTSDNTAANLILANVGGP -AALTAFLRRIGDPVTRLDRTEPELNRPVPGQDLDSTTPRAMARTLRTLLLGDVLSAEASL -QLAAWLRANTTGGKRLRAGLPPDWGVGEKTGTAGR-SANDAGIVWPPRGAPLLVSAYLAD -SEAPAEQREQALAEVARLIAR-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B5D3F3_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGSP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000EF9CE1B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -D---------------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces scopuliridis RB72 TaxID=1440053 RepID=A0A2T7T9R8_9ACTN --------LHELERKFDARLGVYAVDTGTGREV-AYNDGERFPYASTFKALAAGAVLRKYS ---LSGMDRVITYSKDDLIANSPVTEKHVETGMTLKELCDATVRFSDNTAANLLFDHLGGP -KGLEAVLREIGDDVTLMERREPELSRWVPGDTRDTSTPRALVEDLRAFVLGDVLGKAERA -QLTEWLRTNTTGDALIRAGVPKGWVVGDKTGTGSHGARNDIAVVWPPDSAPIVMAIMSNR -PDKDAEHDDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143E694A -hrDTRARLRELEARHGARIGAFAYNLRTRATV-RHRAAERFPICSVFKTLAAAAVLRDLD -RHGETLARRIHYTVADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Janthinobacterium TaxID=2610881 RepID=UPI000A320E98 ----AHTQLAALEQAAGGRLGVSAWRQGGELRI-AHRADERFPLCSTFKAMLAAAVLAHSA -SEAGLLAQRVRYEKKDLVTYSPITEKHLADGMTVAELCAATLQYSDNSAANFLMKILGGP -QAVTAYARSIGNKEFQLERWETELNSAIPGEVRDTASPASMARSMEQLLLGDGLPAPQRQ -QLDTWMRGNTTGDKRIRPALPDGWKVADKTGSGAYGSINDIGVAYPPVGAPLVIAVYYTR -ELKNADNNQDIITAATRIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=A0A1N7EH57_9ACTN ------SQFAALERKHGARLGVYVLETGTGASL-AYRADERFAFCSTFKALAAAAVLHQNP ---VSHLGKRVTYTGADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -ARLTAYLRRLGDTVSRMDNYEPELNRDRPRDPRDTTTPRAIAADYQKLVLGEALSAGKRA -LLKDWLVRNTTGAKRVRAGLPKGWTVADKTGTGDYGRANDIAIVWPPHTAPLVMAIMSDR -PGYHTPPKDSLIAEATARIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E25F02 -------DFKELERTYGARLGVYAVDTDNGREV-AYNDNERFAYASTFKAFAAAAVLRKYS ---LSGMDEVITYSRDDLIAHSPVTEKHVDTGMTLRELCDAAVRHSDNTAANLLFDALGGP -KGLASALEEVGDTATRVERREPELNQWAPGATRDTTTPRAWAGDLRAFVLGDMLGRKERA -QLTKWLRTNTTGDELIRAGVPHGWVVGDKTGGGGYGVRNDIAVVWPPDAAPIVMAIMSNR -GTEDADYDNKLIEEAASVVTR-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. RAC01 TaxID=1842533 RepID=A0A1B3PMR2_9BURK ---RWRETMAGIEQAAQGRLGVAMLDTGTGLAL-GWRQDERFAMCSTFKLVLAGWMLALVD -QGRERLDARVHYAAADVVAYSPVSGPRAGSGLTVAELCAATVSLSDNTAANVLLARHGGP -AAFTAFVRSLGDTVTRLDRTEPTLNEAAVGDPRDTTTPMAMLQTMHKLVLGDALSPASRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR -SSATPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=alpha proteobacterium Mf 1.05b.01 TaxID=1282876 RepID=UPI0009E0102B ----ILETVRTIESRLGGRVGISVHDTGSDQRW-VYRSDERFPISSTFKPFACAAILSRIE -NGSERLHRVIDITEEDLVTYSPVTETRVNTVMTIAELCEATITLSDNTAGNLILESLGGP -KAFTDYMRSIGDDTTRLDRWETDLNEGTPGDRRDTTTPSAATTSLSHLLLGPTLSNSSRE -QLTTWMENDKVADALLRSALPEGWRIADKTGAGGHGARSIIAIIWPTAEKPIVISIYMAE -SEANFAERNEAIAEIGAAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas albilineans TaxID=29447 RepID=UPI0005F3358A ---ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFVLVAAVLQRVD -RGEVGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP -PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLQPASRQ -RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM -ATVDSDARDAALKAVAQAVVAWw ->[subseq from] class A beta-lactamase n=1 Tax=Pectobacterium versatile TaxID=2488639 RepID=UPI000F8CE1B6 --pDTLNTVKDAENKLKARVGYTELDLTNGMILeGYRPEERFPMMSTFKVLLCSAVLSRVD -SGKEQLDRRIHFHQSDLVTYSPVTEKHLTDGMTVGELCDAAITMSDNTAANLLLSTIGGL -QELTIFLRKTGDHVTRLDRWETALNEALLGDERDTTTPKAMAETLHKLLTGKILTVASQQ -QLMDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVIIYLTG -SQATIEERNKQIAEIGTSLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Sediminibacillus halophilus TaxID=482461 RepID=A0A1G9TAA4_9BACI ---DLDEEFSQIEEAFDARLGVYAIDTGTNQSV-KYNPDERFAYSSTFKLLASAFLLKQND ---LKDLEKVVTFGKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLNALGGP -ENYKQALREIGDDVTQPERYETELNEFSPGNKRDTSTPRALANNLRKVVLGDFLPREKQE -LLIDWMKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVIAVMSRH -KKKDAKYDDELVARAAEVTLNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2A8YSH5_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP ---INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEVAVRSSDNTAGNLLFNKIGGP -KGYEKALRQIGDRVTMAERFETELNEATPGDIRDTSTAKTLATNLKDFTVGNALPADKRK -ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSR -DEKEATYNNELIAQAAEVVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces pini TaxID=1520580 RepID=A0A1I4GFS6_9ACTN ----SHERLVQLEREFDARLGVYALATGTGSTI-AHRADERFAFCSTFKGLAAAAVLDRNP ---ISHLDTLVTYTGNDLMPHSPFTRKNVDRGMTIRQLCDAAVRYSDGTAGNLLIRELGGP -EELTAYVRGLGDTVTRMDRIEPEISQAVPNDPRDTSSPRAMGGDYRKVVLGNALSAEKRA -FLRDLLERNTTGDQRIRAGLPQGWRVADKTGTGQYGTLNDIAVAWPPGSEPLVIAIMSSK -AVQDAERDQALLAEAAAYVAK-- ->[subseq from] Beta-lactamase n=2 Tax=Xanthomonas sacchari TaxID=56458 RepID=A0A2P5Z351_9XANT --qTLQQRLAEIERRSGGRLGVSLLD-GSGATLgWQRQDERFPLCSTFKFLLAGAVLQRVD -RGELSLERRLPVRKADLLANAPVSERHVGGSLSVVEMCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDAQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGQVLQPVSRQ -RLIDWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B4AC2E8 --qATHKEFSQLEKKFDAQLGVYAIDTGTNETI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDTLNEVIKFRKEDLVDYSPITEKHIDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGP -KGYEKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKVIATNLKDFTVGNALPDDKRK -VLTDWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRSPIIIAILSSK -DEIEAIYDNQLIAEAAEVVVNTf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110611 TaxID=1621259 RepID=UPI00082BB0DE -------EFKKLERKFDARLGVYAIDTGTGREV-AYNDGERFGHHSTFKAFAAGAVLRKHS ---LGGMDKVIKYSSDDLVDNSPITEKHVATGMTLRELCDAAVRYSDNTAANLLFADLGGP -KALNAVLKELGDDVTRMARIEPELSNWVPGEKRDTSTPRALAEDLRAFVLGDALGKAERE -QLTQWLRTNTTGAELIKAGVPKNWVVGDKTGAGSYGARNDIAVVWPPDGAPIVMAILTNR -TTKDAVFDNKLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=A0A4D4K1T9_9ACTN -------AFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDAMLEKMGDDVIRMERREPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGDGERT -QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVMAIMSNR -GDKDATSDDKLIADAAHVVADQ- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Q8GUV0_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVARPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI0005938A4E ---AANTSVADLEARYDAQIGLFAVDTGTGRTV-THRADERFPFLSTFKALAAAALLRSHP -LDTGYFDRVIRFHEADLVEHSPVTSAGVAEGMTMARVAEAAITRSDNTAGNLLLREIGGP -EGLTAFLRTLGDPASRLDRWETELNTAIPGDERDTTTPAALAADYRASALGDALGAPERD -QLVAWLKANTTGGERIRAGLPANWVTGDKTGTGSYGSANDVAIVWPEGGAPIVIAILSRK -SDADAEANNDLLAEVAKVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cinnamoneus TaxID=53446 RepID=UPI000903B201 -------ELKELERKFDARLGVYAVDTGTGREV-AYNDGARFAHASTFKALAAGAVLKKYS ---LSGLDRRVTYSKDDLVDYSPVTEKHVETGMTLRELCDAAVRYSDNTAGNLLFGALGGP -KGLDAVLEGMGDDVTQMERREPELNLWAPGETRDTSTPRALAKDLRAFVLGDALGKGERA -QLEQWLRNNTTGGELIRAGVPKGWAVGDKTGAGQYGTRNDIAVVWRPGAAPVVMAIMSNR -TKKDDKYDNKLIAEATSVIT--- ->[subseq from] Beta-lactamase n=1 Tax=Fictibacillus arsenicus TaxID=255247 RepID=A0A1B1Z7K7_9BACI -------VFAKLGEKFDAKLGVFALDTGTNQTV-NYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNKTITYTREDLVTYSPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTTPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDKLPTEKRE -LLIGWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPKGDPIVLAVLSSR -DQKDADYNDKLIAEATKEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Modestobacter caceresii TaxID=1522368 RepID=A0A098Y6C6_9ACTN ----VGEALTALEGEFDARLGLYAVDTGSGQVV-AHRADERFGYASTHKALSAAAVLDRTT ---DAELDQVVTYTAEDLVTHSPVTEAHVGAGLPLRELAAAAVQHSDNTAANLLFDRLGGP -AGLEQALRDLGDDVTSVDRTETALNTAVPGDVRDTSTPRALATDLQAVLLGDALDPADRD -LLTGWMRDNATGGTLVRAGVPADWQVADKSGGGGHGTRNDIAVVWPPDGAPIVLAVLSSR -DEADAEYSDALIARATDIAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus massiliensis TaxID=1465765 RepID=UPI0011C7234E --eELAQEFKQLENEFDARLGIYAIDTETEKSV-VYRADERFAFASTYKALAAGVLLDQKT ---MNELEKIITYTEDDLVTYSPITEKHVDTGMSLKEVAEAAIRYSDNTAGNLLFKELGGP -AGFEAALREIGDTVTESVRFEPDLNFTVPGDSRDTSTPRELATNLQTFVLSDLLPSEERE -LMTDWLVGNSTGDTLIRAGVPENWVVGDKSGAGMYGTRNDIAIVWPPDRGPIAISILSDR -DTEDATYDDALIAEAAKIVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Acrocarpospora pleiomorpha TaxID=90975 RepID=UPI0012D349AE ------SRFAALERKHDARLGVYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP ---LSHLNKRVTYTSAEVNSISPITEDHIATGMTIRQLCDAAVRYSDGTASNLLVRDIGGP -AQLTAYLRGLGDTVSRIDNYEPELNRNPPRNPRDTTTPRAIAADYHKLVLGDALTTGKRA -MLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPNTAPLVMAIMSDR -SGYSTPHKESLIAEAAARIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora sp. CWR15 TaxID=2499994 RepID=UPI0013DC34D5 ------VDFAPLEREFDARLGVYAIDTGSGSTV-AHRAEERFAYASTFKALAAGAVLAATS ---DEELDRVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP -SGFRQALREVGDEVTEPVRWETELNAYVPGERRDTSTPRALATTLRAYAVDEALSPADRA -VLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPERAPIVLAVLSDR -TEPDAERDDALLARAAELTLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces roseochromogenus subsp. oscitans DS 12.976 TaxID=1352936 RepID=V6KXM5_STRRC ------AELTDLERRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --RCAPLDTVIHYPPHDILPHSPRTEEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP -DGLTRFFRSLGDGTSRLDRWEPELNTAIPGDRRDTTTPEALGRGFERLTLGRALARADRA -QLVTWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTANDIGVAWTTRGTPVLLTVLSSK -TAQDAAADDALVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0010221E5C ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -S---------------------- ->[subseq from] Beta-lactamase n=1 Tax=bacterium YEK0313 TaxID=1522316 RepID=A0A0A1P325_9BACT --qELGARLAALEARSGGRLGVGVLDTATETRG-GHRVGERFAMCSTFKSIAAAHVLARVD -RGEERLDRRVIFAESDLVPYSPATKPRAGGQMTMGEICEAAVVLSDNTAGNLLLASFGGP -AGLTRFFRSAGDTISRLDRNEPDLNNVAPDDPRDTTTPGAMSETVRQILLGDTLKSASRA -QLTAWMVGMKTGDARIRAGLPSGWRVASKTGSGNGGEANEAGIFWPPGRAPVVLSVYYRK -SEGSADQRNAVIAEAARIVA--- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ad46 TaxID=989432 RepID=UPI0007AEB34F ------DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD -RGEESLGDLVTYKATELVPYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKDWCIADKSGAGYNGSRGIIAVLWPETGKPYLAAAYMSG -SDASFKQRNAVIAEIGKAMIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Halomonas sp. NBT06E8 TaxID=2609667 RepID=A0A644Q7Y5_9GAMM ----ITAELARIEQALDARIGFAAHNLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALETEVSFEESDLVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP -EAVTAFARSMDDPITRLDRYETELNEATPGDERDTTTPNAMLATLEKLVLGDVLADESRQ -QLEAWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQPPTVAVFYITD -TEASFEERNAAIASLGEVV---- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. UNC279MFTsu5.1 TaxID=1502775 RepID=A0A1I3LCC8_9CAUL ----ISRDIAALEARSGGRLGVAVLDTADGKAF-AHRGDERFALCSTFKALVAGLVLKRVD -QGQERLDRRIRYGRGVLTAHSPATEKHVGEGMTVGALCEATVTLSDNAAANLLLHTFGGP -PALTAFLRGLGDTVTRLDGYEPALNVVRPGEIHDTTSPSAMLASLRALTLGPVLSPASRQ -QLAAWLVGNQTGDKRLRAGLPRGWKVGDKTGSWGDGTTNDIAMIWPPGRPPLLITAYLSR -STLDDNGRNAVIAEVARLAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2FMZ2_9ACTN -----DREFRQLEQRFDARLGIYAIDTGTGRTV-GYRAEERFAYASTYKALAAAEVLDETR ---DAELDRVVRYSADDLVTYSPITEQHVAEGMTLRALADAAVRYSDNTAGNLLLRHLGGP -QRFEKELRKIGDKVTDAARYETELNEGTPGDRRDTSTPRALAGDLRAYAVEDALEPADRG -ILNGWLRGNTTGAALIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -GEKDAGYDDALIAQATEVVIT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2FBX4_9BACT ------------EDQLGARVVYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIFAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. musacearum NCPPB 4394 TaxID=1094187 RepID=A0A656S262_XANVA ----LRAQWAEIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD -QGKLMLAQRVKIRASDMLEYAPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRSIGDAQTCSDRHEPDMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK -QLTDWMINNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG -AKVEDAARDAALKAVAVAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI00040718D2 ---MLRAQWAQIERGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas hydrothermalis TaxID=115561 RepID=A0A291JV44_9GAMM ----ITAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGQLALDTEVSFDESALVTYSPVTEQYAGHRMTLFELCDATMTTSDNTAANLILEALGGP -GAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ -QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVVVFYLTE -TDASFEARNEAIAALGDVL---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2L5_9BACT -------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEMLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ -TDASMEQRNAAIAAIGAALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=A0A0Q6XR18_9BURK ------------ETSVGGRLGVAVLDTATGHCS-GHRVDERFPMCSTFKWLAAAVVLQRVD -AGVERLDRALPVAAHDIIDHSPVTVTRVGGTITLGELCEATITVSDNAAANLILAACGDP -AAVTAYARSVGDTVTRLDRNEPSLNEARPGDPRDTTTPAAMAATLNKVVLGDALTRASRE -RLAGWMRGTKTSGDRLRVHLPAGWRLGDKTGSGANGTTNDVGVVWVPGRAPVVVAMYLTE -AGASPAARNAVIAEAGRVVWT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0395 TaxID=1703923 RepID=A0A1Q5C3T0_9ACTN -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAEPERA -RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=A0A2J4QBU1_9ENTR ---AIQQKLADLEKRSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRT -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDCGTTNDIAVIWPENHAPLVLVTYFTQ -PQQDAKSR--------------- ->[subseq from] class A beta-lactamase n=1 Tax=Granulicella sp. S190 TaxID=1747226 RepID=UPI00131CB7E3 ----LPALLAQLEHSNSCRLGVAVLDTASGERT-GHRSDERFAMCSTFKMLLAAAVLQRVD -AGHERLNRNLSVPARPLVSHSPVTEEHAGAEMTVSALCDAILTQSDNTAANLLLDTLGGP -GGVTLFARSIDDKITRLDRTETSLNEALPGDPRDTTSPSAMVENLQKLLLGNVISTSSRN -QLIQWMVANTYGDTRLRKTLSANWKAADKTGANGETTTNDIAIFWPPHHPPVLIAAYLTE -CPGSDDKRNTILAEVGRIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1D3PD80_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS ---LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhi TaxID=90370 RepID=A0A0E3Z6W4_SALTI ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Belnapia rosea TaxID=938405 RepID=A0A1G6TD82_9PROT ----AADALAALESRQGGRLGVAILDTGTGRAL-AHRGEERFPLCSTFKFLAAGLVLARVD -RGEERLDRRVAYGPEALVPYSPVTGPGAEAGMTMGAICDAAVTLSDNTAGNLMLDSFGGP -AGLTAWMRGLGDPVTRMDRREPELNLVPPGDERDTTTPLAMIGLMRALLLGDALRPASRE -QLAAWLVACRTGDRRLRAGLPAGWRVGDKTGTGPDIPTNDVAVAWPPGRAPILIAAYLLG -ARGSEAERSAVLAEVGRIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. ICMP 5592 TaxID=2292445 RepID=UPI001294B709 ---DADKLLADLEKRTGGRLGVSVLDTETNISL-GYREAERFALCSSYKALAAGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCNAAITLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGENGSYADVAVVWLPDRGPILVVTYVGE -ATAPAKDIEAVFAEVGKIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF10870 ------HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF0C34E ------HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Modestobacter caceresii TaxID=1522368 RepID=UPI000568B116 ----VGEALTALEGEFDARLGLYAVDTGSGQVV-AHRADERFGYASTHKALSAAAVLDRTT ---DAELDQVVTYTAEDLVTHSPVTEAHVGAGLPLRELAAAAVQHSDNTAANLLFDRLGGP -AGLEQALRDLGDDVTSVDRTETALNTAVPGDVRDTSTPRALATDLQAVLLGDALDPADRD -LLTGWMRDNATGGTLVRAGVPADWQVADKSGGGGHGTRNDIAVVWPPDGAPIVLAVLSSR -DEADAEYSDALIARATDIAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFB3038 ------HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS131 TaxID=2162711 RepID=A0A2T7KA48_9ACTN -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPESWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus telephonicus TaxID=1714840 RepID=A0A3S0JH58_9BACI ----AEETFRQLESQFDARLGVYAIDTETGKST-SYRADERFAFASTYKALAAGAILEQKS ---LNELDEMITYTKDDLVTYSPITEKHVDTGLSLKDIAEAAIRYSDNTAGNLLFNKLGGP -AGFESALRNIGDMVTESDRFEPDLNFIVPGDTRDTSTPRALATSLQTYVISDLLPSEKQA -LIKDWLVGNTTGDTLIRAGVPKDWVVGDKSGAGSYGTRNDIAIVWPPDRDPIVIAILSDR -NIEDATYDDALIAEAAKIVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Halobacillus aidingensis TaxID=240303 RepID=A0A1H0UE07_HALAD -----NRKFSQLESKFDARIGVYAIDTGTGRTV-AYRPDERFAYASTYKALAAGAILQQNS ---ISELNKVITYTSKDLVTYSPITKMHVDTGMTLRELCAAAIRYSDNTAGNLLLQELGGP -DGFEKALKQIGDNVTQPRRYETDLNEAIPGDIRDTSTPRTLATDLQVFTINNVLPSEKRT -ILINWLRTNTTGDKLIRAGVPKIWKVGDKSGAGGYGTRNDIAIVWPPNRAPIVMAILSSR -DKKNVTYNDALIAKAAKVTIK-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C0LSK3_KLEPN ------EQITRSESQLAGRVGYVEMDL----LA-AWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIRYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMAATLRKLLTSHTLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPNGKAERIVVIYLRD -TPATMAERNQQIARIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. LTSP849 TaxID=1615890 RepID=A0A0D7PUE4_9BRAD -------ELESYERESGGRIGVYAENLATGAKL-IWRADERFVMCSTFKASLAACVLARVD -RGEEQLAATIPYGQADLLDYAPVAKQNLSTGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDSISRLDHNEPELNRSPPGDPHDTTTPAAMANNLRRLVTGEALSQASRA -QLTDWMVNCKTGANRLRGGLPADWKIGDKTGNNGKDASGDIAIVWPKPDRPILIAAYTQG -GTPTAAQIEAVFARIGRMVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces parvus TaxID=66428 RepID=UPI0013BB68F2 -------AFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNAAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSNWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGNYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. KC216 TaxID=2530370 RepID=A0A4R4M9S4_9ACTN ---DVTAKLRRLEETRDVRIGAYAVDTATGRFV-AHRADETFPFASTFKAFACGAVLRKAD -SDPGLMDRVIRYKKSDLAAFSPVTEKHVGTGMTVADLCHATITRSDNTAGNLVLKEIGGP -AGLTAFLRSLGDTVTRSDRWEPGLNDWKPGEKRDTTAPRAWAGSLRALTVGDALAPADRD -RLNAWLKATVTGGKRIRAGLPEGWAAGDKTGTGGYGSANDIAIVWPPSRAPLVIAILTTR -PDAGARTDERAIAETARVLTQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID7982 TaxID=2706094 RepID=A0A6B3FKI9_9ACTN -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Massilia dura TaxID=321982 RepID=UPI0012DA8FEE -------GFDAIEYDLDGRLGVAVIDTATGKVA-GNRLDERFPMCSTFKAILAAQALARDA -REPGFIGRRLRYAKTDLVSHSPVTGRHVAGGMTVAELCAATVQHSDNTAANVLMDELGGP -AALTAFARTIGDTAFRLDRRETALNSAIPGDERDTTTPLAMARTLQKLVIGDALPAPQRL -QLKDWLVGNTTGDNRIRAGLQAGWQVGDKTGTGAYGVTNDIGVVFPPDRAPLVVVVFTHQ -RAKDADSRDDIVAAAARAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02130 TaxID=1703934 RepID=A0A1Q5G2W9_9ACTN -------DFQKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Tuberibacillus sp. Marseille-P3662 TaxID=1965358 RepID=UPI000A1C9AD7 ---KTDEKFDQIENEFNARLSVYAIDTGSNQTI-EYRPDERFAFASTYKALAAAIVLQQNT ---MEELKEVITYTKDDLVPYSPITKKHVDTGMALLKLAEAAVRSSDNTAGNLLLKALGGP -DGFEQALRQIGDNVTQADRYEPNLNEFTPGDTRDTSTPKVLATDLQAFAVGDLLSNDDRE -RFTNWLQGNATGDTLIRAGAPKGWEVGDKSGAGNYGTRNDIAVVWPPNREPIVISIMSRH -DTEDAKYDDTLIAQAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Paludifilum halophilum TaxID=1642702 RepID=A0A235B725_9BACL ---AVTDDFAKLEEKFDARLGVFALDTGTNQTV-TYRPDERFAYASTHKALSVGALLQQKS ---IEDLDQKITYTRDDLVNYNPITEKHVDTGMTLKELCDASLRYSDNTAANLIFEQLDGP -RGFKKSLREMGDNVTNPERIEPELNEVKPGETHDTSTPRALATSLQAFTIGEALPTEKRS -LLTDWMKRNTTGSTLIRARVPKDWKVADKSGGAGYGIRNDIGIIWPPKSDPIVLAILSHR -DKKDDEYNDKLIAQATKEVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=A0A560AQI6_9ACTN ---AADQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADDRFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPVTEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPARAPIVLAVLSSR -DKKDASPDDAVIAQATRVVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Aquabacterium sp. SJQ9 TaxID=2493092 RepID=A0A3R8S7K1_9BURK ----WRQRLWALERNSGGRLGVAALDLHTGARL-AWRADERFPMCSTFKLPLAAMVLQRAD -RGQERMDRLLLIDKAALVPHSPITERHVGEVMTMTQLARAAVTVSDNTAANVLLRELGGP -AAFTAFERSLGDATTRLDRYEPDLNDTPPADERDTTTPAGMLAGLQQAVLGDALSPASRE -LLVRWMRETKTGEHRLRHAVPPDWQPGDKTGTGAPGTANDVAVFWPPGRQPVLVTAYLTQ -ATLPAEGCEAVLADVGRLVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. (strain 170) TaxID=74566 RepID=Q45414_BAC17 -----NQSFVKLEKEYDAKLGIYALDTSANQTV-TYRSDERFAYASTHKALAVGAVLQKKS ---IEDLEQRIKYTSKDLVNYNPITEKYIDTGMTLKELMDASIRYSDNTAQNLILTQLGGP -SGIQKIMREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSVENRN -FLIDLMKRTTTGDNLIRAGVPGEWEVPDKTGSGSYGTRNDIAFIWPPNKKPFILAILSNQ -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DBFE121 ---AADHEFRRLEEQFGARLGIYAVDTGSGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSPRDLVAHSPVTGKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALQPADRD -VLIGWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DKKDATPDDAVIAQAAEVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF91D04 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces globisporus C-1027 TaxID=1172567 RepID=A0A0U3MMJ8_STRGL -------DFQKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis subsp. spizizenii (strain TU-B-10) TaxID=1052585 RepID=G4NPW6_BACPT -----NKKFVQLEKKFDARLGVYAIDTGTNNTI-AYRPNERFAYSSTYKVLAAAAVLEKNS ---IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=UPI000DC64CF1 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPEDALIAEAAEVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sulphureus TaxID=47758 RepID=UPI000372497A --qQTTREFAALERKFDAKLGVYALDTGSGKEI-AHRPDTRFAHASTFKALLAGVVLEQTS ---AAGLDERVEYTEKDLPEYSPITERHASDGMTLRELCDAAVRHSDNGAANLLIRHLGGP -AELQKALRASGDRVTHTDRYETELSAAEPGDVRDTSTPRALAGSLRTYAVQDALPAKKRA -MLTDWLKRNTTGDDLIRAGAPKGWKVGDKTGNGGYGTRNDIAVVWPPKSDPIVLAILSKR -DTKNAEHDDALVADAAEVALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Leaf13 TaxID=1736211 RepID=A0A0Q6H584_9BACI -----NHDFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ------INQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQAFTLGDTLPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DKKDADYNDKLIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus vallismortis TaxID=72361 RepID=UPI000C29F514 -----NEKFVQVEKKFDAKLGVYAINTGTNKTI-SYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEIAEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNNLTPDKRT -ILTDWMRGNATGDELIRAGAPIGWLVGDKSGAGSYGTRNDIAIVWPPHRAPIVVAILSNR -FTEDAHYDNALIAEAAKVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=UPI0009AE47AC -----NKKFVQLEKKFDARLGVYAIDTGTNNTI-AYRPNERFAYSSTYKVLAAAAVLEKNS ---IEKLNEVIYYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAIPGDIRDTSTAKALATDLKAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSKR -FTKDANYNNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=I7AP07_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKXLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAXXRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIA---------- ->[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sediminis TaxID=547162 RepID=A0A1I1J794_9ACTN ------VDFAPLEREFDARLGVYAIDTGSGSTV-THRADERFAYASTFKALAAGAVLAATS ---TEELDQVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP -SGFMQALREVGDEVTEPVRWETELNAYVPGERRDTSTPEALATTLRAYAVDDALSPDDRA -LLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPDRAPIVLAVLSDR -AEPDAERDDALLARATELTLD-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A5D4INT7_9ACTN -------AFRKLEREFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYAREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEC1057 -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKALQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A1S6R9P0_STRHY -----TGEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVIKYSKDDLVDNSPVTEKHVDTGMSVGALCDAAVRYSDNAAANLLFDELGGP -KGLDAMLEKMGDDVIQMERREPELSRWVPGSTQDTSTPRAMAKDLRAFVLGDVLGDGERA -QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVVAIMSNR -ADKDAKSDDKLIADAAHVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI001117CDE8 --qTLQKKIEMLENKSGGKLGLTVVDTSDGTTY-SWRGDEKFPLCSTSKVMVVAAILKKSE -SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP -RYATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMAETLNKLILGNALKKEQKA -KLTEWMKGNTTGLNSIKAGLPAEWIVADKTGSGDYGTTNDVAVIWPKNHAPVILTTYFTQ -PEKDASARKDVLASAAKLIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4MSK11 TaxID=1927960 RepID=A0A370WVG4_9GAMM ---DVRAKLAALERKHGGRLGVAVLDTGSGRSV-GHRADERFMMCSTFKMLLAAATLDRVD -RGAEQLDRHLIFGKDAVLSYAPVTQHHVGLPMSIADLCKAAVSLSDNTAANVLLANLGGP -AAVTAYARQLGDTMTRLDRNEPELNRPSPDHVSDTTTPASMLNNLRTLVLGHVLRDESRK -LLTEWLRETTTGKNRLQAGLPAGWVTGDKTGSGYD-ATNDVAIMWPPQRKPLLVSAYYSA -ANLDDDARSAVLADVGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. JS01 TaxID=1525753 RepID=A0A087K7P2_9ACTN -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase SME-3 n=1 Tax=Serratia marcescens TaxID=615 RepID=Q6PRG8_SERMA ---AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYYSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA -IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR -KSKDDKHSDKTIAEASRIAIQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AC27/96 TaxID=1841653 RepID=A0A1B9SDG5_9RHIZ ---DVDKQLADLERKTGGRLGVSVLDTETNISL-GHREEEHFPLCSTYKALAVGFVLARVD -QGVEKLDRRVAYGKDKVVTYSPETEKHAGTDMTIAELCGAAITLSDNTAGNLLLESFGGP -AALTAWLRTTGDTETRLDRNEPDVNQAIKDDPRDTTTPDAMLDSIGLLTLGNTLSETSRD -QLVNWLVGNTTGNNRLRAGLTKEWKVGDKTGTGNNGSYADVAVIWPPERGPILVTTFVAE -GTAPAKDIEVVFAEVGKIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A2B1FG53_BACCE ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNP ---INKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNLLFNKIGGP -KGYEKALRQIGDRVTMAERFETELNEATPGEIRDTSTAKTLATNLKDFTVGNALPADKRK -ILTDWMKGNATGDKLIRAGVPTDWEVGDKSGAGNYGTRNDIAIVWPPNRAPIIIAILSSR -DEKEATYNNELIAQATEVVTN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182) TaxID=288000 RepID=A5EJY1_BRASB ---DLQQTIAGIEADCGGRLGVALLDSASGALS-GHRLDERFPMCSTFKALLAAAILTKVD -AGAEQLSRRIPIAQADILSYAPVTKQHVGTSLSVGELCEATVTLSDNTAANLLLATLDGP -AGLTRTIRGFGDAITRLDRIEPGLNESIPGDPRDTTTPAAMAQTLAKLTVANTLSAASRD -VMNGWLIGCKTGAAKLRAGLPAEWRVGDKTGAGDHGSSNDVAVIWPAGRGPVIVTSYLTE -TKASDDRRNAAHAAVGRAVAA-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JQZ2_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSSKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMD----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001118893C ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter piscinae TaxID=1580596 RepID=A0A291G7G1_9RHOB --qDLQNTVADWEERLNARIGVVLRDTSSDWEI-SMRAEERFPMSSTFKSLLCGAVLSRVD -AGQEDLDRRVTYAEGDLVAYSPVTEQHLDNGLTVGELCEATVTLSDNTAGNLLLDTVGGP -EGLTNFLRDIGDQTTRLDRWETALNEAAPGDPRDTSTPSAILNTLETLLLGDVLEPATAA -QLRQWMIDDQVADALIRAHLPEGWVIGDKTGAGGNGSRAIIAFIEPEADVNYFAAIYLTE -SDADFALRNQVVSEIGQAMI--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sanxanigenens TaxID=397260 RepID=W0ADZ5_9SPHN -----TEQMQAIERESGGRLGVALIDTGNGRRF-AWRGEERFPLCSTFKLLLAGATLARVD -SGEERLDRRVAVTEKDIIAHSPVTGEAVGGTLSVDELCAATLTTSDNAAANLLLAPLGGP -EKLTAWLRAIGDPVTRLDRPEPFLNESKEGDPRDTTSPVAIAEDLERLVVGTALSAASRT -RLARWLEANQTGDNRIRAGAPKGWRIGDKTGTGERGATNDVAILWPPSGKPLLLSTYLVG -SSAEQAAREKVLASAARSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Frateuria sp. Soil773 TaxID=1736407 RepID=A0A0Q9PNU4_9GAMM -----AARLAALERRHGGRLGVSILDTGNGRRA-SHRGGERFLMCSTFKLLAVAAVLMRVD -HGEERMDRRIVFGKDVLLSYAPVARRHVGAPMSVEELCAAAITLSDNTAANLLLASMGGP -AAVTALARRLGDGVTRLDRNEPMLNVGSPGDLRDTTTPDAMLATMQKLLLSHALADASRE -RLLAWLRACTTGFEKLRAGVPPGWTVGDKTGSGPKGESNDVAILVPPGRKPLLVAAYYAD -SPADDAARNAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=W9G608_STRFL -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAFNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLERLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPEDRLIAEAASVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-475 TaxID=1463910 RepID=UPI000A5C4032 ----VTARLRELERKHTARLGVYGRNLRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -REGEFLARRIHYTQEYVTKYSPVTEDHVATGMTVGELCDATIRFSDNTAGNLLLEELGGP -TAVTRFSRSVGDRITRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALEPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=UPI000E0DEBF4 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPADKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPEDALIAEAAEVALEAf ->[subseq from] Beta-lactamase n=1 Tax=Ramlibacter henchirensis TaxID=204072 RepID=A0A4Z0C866_9BURK -------KWTALEMLSGGRLGVAVLQ-ADGRID-GHRLDERFPMCSTFKWLAAACVLRRVD -AGQEQLDRTIPFGADALLAHSPVTQEHAGNGMTLAQLCAATIAVSDNAAANLILSTFGGP -AGLTTYARSLGDTVTRLDRWEPDLNEATPGDPRDTTSPRAMAGLLHATLVGNALSSASRE -QLGRWMEATRTNEKRLRADLPSGWRMGSKTGTGARGTTNDVGIFWPPGRPPVVVVAYLTQ -TDAPEADRNAAVAEVARRMV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium endolithicum TaxID=1191678 RepID=UPI00115A1DCC ---TVAETAAEVEADLGGRVGVLLQQYGEAPAA-TYRADERFPLASTFKALACGAALSRVD -AGEQDLEAIIKYGADDIVTYSPITEKHVGVGMTLGDLCHATITLSDNTAGNLVLDSVGGP -SGFTAFMRKIGDEVTRLDRWEPELNEALPDDPRDTTTPRAVVTTLERLLLGDVLLPASRR -QLEEWMIADQVADKLIRASLPKGWTIGDKTGAGERGSRSIIAIIRPPQGKPWLAGIYLTG -SDADMDKRNEAVAMVGAAIVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sp. AG TaxID=2681969 RepID=UPI0012EB8884 --qTIDNHFAQLEKEFDAKLGVYAIDTGSGKII-DYQADERFAFTSTVKALAVGAVLQQNT ---MEELNETVTYTKDDLVTYSPITEKHVDSGMTLLELSEAAIRYSDNTAGNLLFNELGGP -DGLEKAMRDIGDTVLHSNRTEPNLNEAQPGDIRDTSTPKALVTSLQAFALDDLLSKPKQD -MLLEWLQTNTTGDTLIRAGVPEEWTVGDKSGAGGYGTRNDIAIVWPPDQEPIVIAILSSR -DTEDASYNDDLIKQATEITVD-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL25I1N1 TaxID=1938804 RepID=A0A2T0QSZ1_9BURK ---AVRRRLVEIEAASGGRLGVSIVDTMSGLHA-GLRTDERFPMCSTFKMLMAGAVLARTD -RGEEDLQRRVVFSQSDVVSNSPATSKHTRELMSIAELCKAAITLSDNAAANLLLATFGGP -AGLTAFARSLGDGVTRLDRIEPMLNEGTPGDLRDTTTPNAMLGNLRELLLGERLSSSSRA -QLLAWLAANETGGARIRAKLPKDWGVGDKTGTGDHGTANDIAILWPPGRGPVLVTVYLTE -TDGNAARSNAAIADVGALVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 3180 TaxID=2682611 RepID=UPI00135B9A70 -------SLAALEREYGARVGVYAVATDTGATV-VHRADERFALCSVFKSLAAAAVLDRDP ---LDRLDQRITYTRDDLAAHSPVAEKHVATGMTVRHLCDAAVRYSDNTAANLLLRHLGGP -RALTTYLRGLGDRVSRLDHYEPELNTNPPGDPHDTTTPRAVAADHRALVLGDALPAAKRD -LLKDWLVRNTTGDRRIRAGAPRGWTVGDKTGTAEWGRANDVAVLWPPRAAPLVLAVLTDR -PDRGAAPSEPLIAEATRRT---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces acidiscabies TaxID=42234 RepID=A0A117E9V7_9ACTN --aATRDVFAGLEQEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLREGV -----DLTRRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP -TAITRFARSLGDSVTRLDRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRT -RLTSWMVANSTNVTRFRAGLPADWILADKTGGGSYGVANDVGVVWPPGRAPLVIAVLTTT -YAAEGPSKNELVARAAELVAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3605 TaxID=1609103 RepID=A0A0X3XGU7_9ACTN ---DVRARLRELERGHGARLGVFAHNVATGRTV-AHRADERFPVCSLFKPLAVAAVLRDLD -RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP -TAVTRFARSLGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGRDYARLVLGDALGARDRA -RLTHWLLHNTTSANRFRAALPPPWTVADKTGGGSYGANNDAGIVWTEAGVPLVLAVMTTR -PEQDAAYDHALIVEATRLVAD-- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Legionella clemsonensis TaxID=1867846 RepID=A0A222P2W1_9GAMM ----IEKKFEVLEASMNGRIGVFAINTANNQHI-QYRADERFPIQSTFKVMAVSAILKQSM -TDKHLLQQKMTYTKKDLVFWSPITEKHLASGMTISELCSAAIMYSDNTATNLIVKKLGGP -NAVTAFARSIKDSTFRVDNWEPELNSN-PNNLLDTSTPIAMEKSLQKLTLGNTLALPQRE -QLVTWMKNNTTGDARIRAGVPKRWIVADKTGSGGYGISNDIGIIWPPSCAPIVVTIYSVH -NEKATTPRDNVIASATRLIIKEf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A1B1L1C3_BACTU -----NQSFAKLEKEYVAKLGIYAFDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. AC87j1 TaxID=2055894 RepID=A0A2S6MNW8_9BRAD -------EFETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYGKADLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0D810_9NEIS ----TARQLAELERNAGGRIGVFAQEVDSGRSL-AYRANDRFPMCSTFKLLLVGALLQRSA -TQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEELGGP -QEVNRFARSLGDGLTRLDRIEPELNRAEPGDPRDTTTPAAMTANLHALLFSPLLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG -SPAMMDERNAVIAAVARVAAAEf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DH-12 TaxID=2072509 RepID=A0A2K2RJD5_9ACTN -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLGERIPYGTADLVPHSPVTEKHTGKGMTLRELCDAAVRYSDNTAANLMLRDIGGP -RGLTAYARRLGDRATRLDHTEPELNSNPPGDPRDTTTPRAIAGDYRALVLGDALPAAGRA -LLTDWLVRNTTGDRRVRAGAPRGWRVGDKTGGGEWGRANDVAVLWPGGRSPLVLAVLTER -PDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. WSM3864 TaxID=2029404 RepID=A0A2A3CKI5_9RHIZ ----ATKAVEALESRNGGRLGVMVLGTGTDAAI-EYRADELFPITSTFKFLAAAGVLKAVD -DGKARLDDRIVYAASDVEPYSPVTKEHSGEGMTLEDVCAAAVVWSDNTAGNLLLRVLGGP -QGLTRFARTLGDDVTRLDRTEPTLNTAIPGDKRDTTSPRALLGDARRILLGDALSPASRK -RIEAWLIEDKVGGARIRAGLPAAWGIGDKTGSGDNGTTNTVALLWPPNGAPILAAVYYTG -STAPRASREAVHADVARIIVETf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SS07 TaxID=2015315 RepID=UPI000B5C9B4B -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPDLSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2B4XFI2_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-TYHSDDRFAFASTSKSLAVGALLIKNS ---LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes italicus TaxID=113567 RepID=A0A2T0K372_9ACTN ---DTARAFDGLERRFDARLGVYALDTATGRTV-THRADERFAHASTFKALQAGAVLRRAT ---DADLRKVVKYRRADLLAHAPITSKHVATGMSLDDLLAASVRYSDNTAANLLFEHLGGP -EALERELRALGDRTTSVDRIEPHLNEAEPGDTRDTSTARALGTTLHTLVLGDALPTARRE -RLTAWLRGNTTGDPYIRAGVPPGWQVGDKTGTGGHGTRNDIAIVWPPAGAPLVIAILSDK -GERDARPADTLIAEATETVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=A0A562WBA8_9ACTN --------FGALEARYGARLGVYAVDAGSGATV-VHRADERFAYASTFKALAAAALLDATT ---AQELDRVVRYTRADLLPHAPVTGRHVGTGMSLRDLAEAAVRHSDNTAANLILAELGGP -AGFAGHLRALGDRTTKPTRTEPALNEATPGDDRDTSTPRALATDLRAYVLGDALDAEDRA -LLTDWLRRNTTGGGLIRAGVPAGWLVGDKTGTGGYGTRNDIAVLWPPGRAPIVLAVLSSR -DAEDADHDDALIAEATRVTLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces toyocaensis TaxID=55952 RepID=A0A081XRD0_STRTO ------DSFKELERKHGARLGVYAVNTGDGREV-AFNADERFAYASTFKAFAAAAVLRKYS ---LSGMDKVIKYSRNDLIDHSPVTEKHVDSGMTLRDLCDAAVRYSDNTAANLLFDALGGP -QGLAAALAETGDTTTQVVRREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE -QLTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPDAAPIIMAIMSNR -GAEDAEYDNRLIAEAASVVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=A0A1C4CSL0_BACCE ------HSCVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSITNPERFEPELNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGNNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADASKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=UPI0009FD87C9 ---ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2L1J0T7_ACIBA ----------DAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQXQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATM------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Halobacillus hunanensis TaxID=578214 RepID=UPI0009A69854 ---KTDEKFSKLENEFDAQLGVYALDTGTDQTI-EYQSEERFAFASTYKALAAAIVLQQKS ---KDELEEVITYTEDDLVTYSPVTKKHVDTGMTLLKLSEAAVRTSDNTGGNLLFKTLGGP -NEFEQALRQIGDNVTQADRIEPELNEFTPGDTRDTSTPKALATSLKEFAVGDLLSNDKRE -LFTDWLKGNATGDALIRAGAPEGWVVGDKSGAASYGTRNDIAVVWPPNREPIVIAIMSHR -DQENAQYNDELIAQAAEIALN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=H1AFJ2_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVRELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYSAG -NTPGEHG---------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces megasporus TaxID=44060 RepID=UPI0004E20BC8 -------PLRALERKHDARLGVYALATGTGKAI-AHRADERFAFCSTFKTLAVAAVLHRNP ---LSHLDEHVTYTWDDIKSISPITRQNVAKGMTVGQLCDAAIRHSDGTAANLLLRDLGGP -ERLTAYLRKLGDTVSRLDRYEPELHQARPGDPRDTTSPRAIAADYRTVVLGDALAADKRA -LLTDLLVRNTTGGNRIRAGLPKGWRVADKTGTGNYGRANDIAVVWPPRSAPLVMAIMSER -SEQEDRPSEALIAEAAEHIA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03238 TaxID=1907777 RepID=A0A1X1N6Y6_9ACTN -------QLRALERRHGARLGAVARNTVTGATV-LYRADERFPMCSTFKTLAAAAVLRDLD -RHGEVLAKRVRYTRDDLVENSDKAEEYLATGMTVAELCWAAICFSDNTAANLLLRELGGP -AAVTRFCRSLGDGVTRLDRWEPQLNTAEPWRVEDTTTPAAIAGTYERLVLGTALNRPDRE -RLTGWLLANTTSTYRFRAGLPADWRLADKTGGGAYGTNNDVGVAWTPDGAPVVLAVLTTK -PEQDAPADNPLVRDTASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. Mc5Re-14 TaxID=1030529 RepID=UPI000B882E22 ------VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEKHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTFDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTKDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00062D1C9A ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTC -QT--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus tibetensis TaxID=336292 RepID=A0A1G5K8V8_9RHOB ---TIEDAARAIEAELGGRVGVALRRQGSPAEFfGYRSDERFPLSSTFKAPLCGAILTLVD -AGEDQLDRVIGYTSADLVTYSPVTEARVDSGMSVGELCEATITLSDNTAGNLLLQRVGGP -EGFTEYLRAIGDETTRLDRWETDLNEGTPGDPRDTTTPEAMVATLEKLLFGEILSESSRA -QLNAWMEADQVADELLRASLPEGWIIGDKTGAGGHGSRSIIAVIRRPHDTPWLAAVYLTG -NEADMPTRNRAIARIGAAMVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Niveispirillum irakense TaxID=34011 RepID=UPI00049032F7 ---AMKADIAALEKKAGGRLGVALLDTATGAAM-DWRGGERFAMCSTFKFLASSFILSRVD -AGKERLDRAVPVTKADLVPWSPLSEPHIGGTMTMAALCEAAMIQSDNMAANLLLDQSGGP -AALTAYLRHLGDQTTRLDRKEPKMNNVPENDPRDTTTPLSMLGLMRTILLGDALSAASRE -RLTGWMINNKTGDTRLRAGLPGGWRIGDKTGGSDE-ASNDIAILWPPGGGPLLLASYYIN -GKVPTAQRNAVHADVARLVAGAw ->[subseq from] Beta-lactamase protein n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=H9BW95_VIBAL --dTLTQQVAQLESQSGGRLGVAVLDTQNNHQW-QYRGDERFPMMSTFKALMCASALDLAD -QNKLSLNDTTTIKESDLVTWSPVTEKLIGQDMTIQQACEATMLMSDNTAANIVLHQIGGP -QQVTQFVRTLDDKVTRLDRYEPELNQATPGDKRDTTSPHAMVTSLNTILLQDGLSEKNQQ -TLLTWMKNNKISDSLIRSILPQGWSIADRTGAGEQGSRAINALVWNEQHKPIIISLYLTH -TELDIAQRNQTLNQVAKLVLEHf ->[subseq from] Class A beta-lactamase n=1 Tax=Janthinobacterium sp. TaxID=1871054 RepID=A0A349L0P2_9BURK -----QSRFAELERGTGGRLGIAAIDTGSGRQI-DYRSSERFPLCSTCKIMVTSAILSHSA -NDEALLQRRLKYPKSELVANSPVTEKNHDKGMTVAELCAAAMQYSDNTATNLLLKVLGGP -AAVTAYARTIGDSVFRLDRRETMLNTAIPGDERDTSTPLAMMLSLRKLGLGEALGPAQQE -RLQQWMLGCTTGAEKIRAGVAANWKVGDKSGGGAFGTTNDVALLWPPGREPIVLAVYFTQ -PEKDAKTRNDVVAAATKLS---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A4R4BIR3_BACTU -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADTTKIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI00064557F8 --eDADKQLADLEKKTGGRLGVSILDTETNISL-GYREAERFALCSSYKALAAGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHADTDMTIAELCSAAVTLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAVKDDPRDTTTPDSMLDTIGLLTLGNTLSDTSRD -QLSSWLVNNTTGNARLRAGLPKEWKVGDKTGTGENGSYADVAVIWPPERGPILVVTYVGE -ATAPAKDIEAVFAEVGKIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. LLH-Irr-2 TaxID=1564862 RepID=A0A097SRQ8_9SPHN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIVDKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMD----------------- ->[subseq from] Beta-lactamase n=1 Tax=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) TaxID=369723 RepID=A4X4X3_SALTO ---DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYASTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIAEAAVRYSDNTAGNLLLDHLGGP -ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD -TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000B4566A9 -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Nocardia TaxID=2637762 RepID=UPI00135828DA -------SFAEMETTHSARLGVYAIDTGTGRTV-VHRDGERFPIASTFKGLACGALLRDHP -LATGYFDQVIHYSRSELVLNSPVTEKHVDTGMTVAELCDATITLSDNTAGNLLLKLLGGP -EGFTAFLRSIGDTVSRLDRWEPELNTAIPGDERDTTTAAALATDYRNLVLGDILAEPERA -QLKSWLVAAKTGDARIRAALPADWTVGDKTGSPAYGGALDVAIAWPPGRAPLVIAVLSTK -FEQNAEADNPLVAEAARAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=A0A410KEN5_9ENTR --qTLQKKIEMLENKSGGKLGLTVVNTSDGTTY-SWRGDEKFPLCSTSKVMVVAAILKKSE -SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP -RYATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMAETLNKLILGNALKKEQKA -KLTEWMKGNTTGLNSIKAGLPAEWTVADKTGSGDYGTTNDVAVIWPKNHAPVILTTYFTQ -PEKDASARKDVLASAAKLIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000B927801 -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T322_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQEISLDALCGATMRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -ILTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CEV 2-1 TaxID=2485153 RepID=A0A3N1TKG8_9ACTN ---RTEQAFRTLERKFDARLGVYALDTGNGRTV-THRPDERFAYASTCKALLAGAVLDKNS ---LRQMDRLVRYGRDDLVSASPITEQHVATGLTLRELCDAAIRYSDNAAANLLFHELGSP -RALQDALRALGDNVTRCDRYETALSAATPGDLRDTSTPRALATDLRAYVLGTTLPADKRA -VLTDWLRRNTTGDNTIRAGAPDTWQVGDKTGTGGYGTRNDIAIVWPPGAAPIALAVLSRR -DTKDAERDDALIARAAKVAL--- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. puntauvense TaxID=1398201 RepID=A0A077NHD0_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMAVSALLKKSE -TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLGQLGGA -HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT -QLVEWLKGNTTGGTSIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ -PSKDAKAHNDVLAATARIMTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Go-475 TaxID=2072505 RepID=A0A2Z5JV49_9ACTN -----TARLRKLEQEHTARLGVYARNLRTGRTV-AYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTDHSPVTEDHVATGMTVAELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYARLVLGDALQPRDRA -RLTDWLLRNTTSAEKFRKALPADWLIADKTGGGRYGGNHDVGLTWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGTAQLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013E322C2 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNARIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQSLPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. FJAT-22058 TaxID=1581037 RepID=A0A0M1NVA7_9BACI ----TIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02115 TaxID=1703939 RepID=A0A1Q5IAB4_9ACTN -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLQAFVLGDALAKPERA -RLAQWLTANTTGGELIRAGVPKGWAVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI0002E10915 ------ASLDAVEARYGAQVGLFAVDTGTGATV-THRADERFPFLSTFKALAAAALLHAHP -LDTGYFDRVIRFHEADLVEHSPVTSAAVADGMTLAQVAEAAITRSDNTAGNLLLRELGGP -EAFTAFLRRLGDPTSRLDRWETELNTAIPGDERDTTTPAALAADYRAVVLGDALGARERE -QLIAWLKANTTGAERIRAGLPPAWVTGDKTGTGSYGSANDVAIVWPEGGAPLVIAIQSRK -SDEAAEVNNALLAEVTKAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=A0A543VZ70_9ACTN ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALAADLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPEDALIAEAAEVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia kururiensis TaxID=984307 RepID=UPI0003499DBE ---SVRDALAALERTSGGRLGVCAIPTCKPREI-RYRADERFPFCSTFKVVLAAAILARSL -DVPDLMQRRIRYTKHDLAHYSPVSSKHVKDGMTVAELCQAAIQYSDNTAANQLMKVLGGP -QAVTAYAHATGNAAFRLDRWETELNTAIPGDLRDTSTPAAMARTLQTLTVEQALPSAQRD -QLVTWLRGNTTGAHRIRAGVPADWQVGDKTGTGDYGTANDLAILWPPGRAPVMLAVYFTQ -REPKAKARDDVIAAAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143E657A -hrDTRARLRELEAGHGARIGAFAYNLRTKATV-RHRAAERFPICSVFKTLAAAAVLRDLD -RHGETLARRIHYTVADLAGYSPKTGEHLADGMTVEELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PARDAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BFB51F7 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQTYVLGQALPENKRA -LLTDWMKRNTTGDALIRASVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=2 Tax=Halobacillus karajensis TaxID=195088 RepID=UPI0008A76C23 ----ASGKFSQLENEYNARLGVYAIDTGSNQTF-GYRPEERFAFASTYKALAAAIVLQQST ---MNELKEVITYTEDDLVSYSPITEKHVDTGMNLLELAEAAVRTSDNTAGNLLFKVLGGP -DGFEQALRQIGDNTTQSERYEPDLNEFTPGDNRDTSTPKALTTDLQAFAVGDLLSDDERE -RFTNWLQGNATGDTLIRAGAPEGWKVGDKSGAGSYGTRNDIAVVWPPNREPIIISIMSRH -YTEEAKYDDALIAQAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PBH53 TaxID=1577075 RepID=A0A0H4CAB5_9ACTN -----RAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLDRVVHYPPHDTLLNSPRTAENVATGMTVADLCAAAIQYSDNAAGNLLLREVGGP -AGLTRFYRSLGDEVSRLDRWEPELNAAIPGDARDTTTPEAIAESLERLTLGRALAGADRE -RFVGWLKGNRTSDERFRKGLPKDWTVADKTGTGDYATANDIGVAWTTRGTPVVLAVLSSK -STPDAPVDQALIADAAAVVAR-- ->[subseq from] Beta-lactamase n=2 Tax=Achromobacter sp. SLBN-14 TaxID=1072374 RepID=A0A542KGX9_9ACTN ---ATTGRLTELEREHGARLGVFARNLRTRHTV-SHRADERFPICSVFKTLAAAAVLRDLD -RHGEVLSRRIHYTRDDLVDGAPVTDEHLAHGMTIAELCDAAVRYSDNSAGNFLLRELGGP -TAITRFARSLGDPVTRLDRWEPELNSAEPGRRTDTTSPRAIGRTNARLLLGDALNRTDRA -LLTHWLLNNTTGGARIRAGVPGTWTVAEKTGSGAYGTTNDVGVARTPDGAPIVLSVLSTR -TDRDAAWDNTLIASTAGVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Consotaella salsifontis TaxID=1365950 RepID=A0A1T4SYN8_9RHIZ ----IATAVAEVERTLDARVGVAVLDTGTGHHW-SHRGAERFPMASTSKAFACATLLKEVD -AGRKSLDETVAVEKDDILSYAPVTKDKVGEKMSLGALCEAATGQSDNTAINLALEAIGGP -AKVTAFIREIGDTETRLDRTEPELNEGTPGDPRDTTTPEAAVASLKALVLGDALSEKSRA -QLETWLENDKVAGPLLRASIPTGWRIADRSGAGGHGTRGIVATIWPPKRSPVVVAVYLTE -TDADMDKRNAAIAAIGSALVK-- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii (strain SS-2004) TaxID=406818 RepID=D3V277_XENBS --nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYRAHERFPLCSTSKMMAVSALLKKSE -TNEGLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAKLSAATIQYSDNTAMNLLIDQLGGT -HDVTRFARSIGDNEFRLDRKEPELNMVTPDDERDTTTPQAMADSLYKLALGNTLAATQRA -QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDNKAPLILVTYFTQ -PNKDAEAHPDVLAAAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEE51A5 -----NQSFAKLEKEYDAKLGIYALDTGTNQTI-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGLEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI000417B3F0 ---DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYASTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVAEAAVRYSDNTAGNLLLDHLGGP -ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD -TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=4 Tax=Salmonella enterica I TaxID=59201 RepID=I1W5J9_SALIN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDG -ES--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces violaceusniger TaxID=68280 RepID=A0A0X3WPI7_STRVO ------GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVITYSKDDLIDNSPVTEKHVDTGMSLAALCDAAVRYSDNTAANLLFDQLGGP -TGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAEDLRAFVLGDVLGDGERA -QLTKWLRTNTTGDALIRAGVPKNWQVGDKTGTGSYGGRNDIAVVWPPDSAPIVMAIMSNR -GDKDATSDDKLIADAAHVVADQ- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=UPI00119E8E65 --------FGALEARYGARLGVYAVDAGSGATV-VHRADERFAYASTFKALAAAALLDATT ---AQELDRVVRYTRADLLPHAPVTGRHVGTGMSLRDLAEAAVRHSDNTAANLILAELGGP -AGFAGHLRALGDRTTKPTRTEPALNEATPGDDRDTSTPRALATDLRAYVLGDALDAEDRA -LLTDWLRRNTTGGGLIRAGVPAGWLVGDKTGTGGYGTRNDIAVLWPPGRAPIVLAVLSSR -DAEDADHDDALIAEATRVTLD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T218_9BACT -------AAQQAETELDARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQEISLAALCGATMRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas lenta TaxID=1141887 RepID=A0A2A2SED3_9SPHN ----------LLEREAQGRLGLAILDTGTGARF-SHRADERFPMCSTFKLPLAAAVLAEVD -RGRERLDRRIAIAASDIVAHSPFAKPRVGGATTVAELCEATTTESDNAAANLLLPAVGGP -AGLTRFMRALDGGVSRLDRLEPVINESLPGDPRDTTSPAAMLAMVRRFALGDALSAASRE -RLVGWMIANKTGGRRLRAGLPADWRVGDKTGAGERGSDNDVAILWPPNRRPILVASYLTQ -TPLPFERTNAVHARLARLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. FJL06 TaxID=2153365 RepID=A0A3N7E2E1_9BURK ---TWNETLAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGRERLDARVHYAATDVVAYSPVSGPRAGNGLTVGELCAATVSLSDNTAANLLLARHGGP -AGVTAFVRSLGDTATRLDRTEPTLNEAKVGDPRDTTTPLAMLHTLHKLVLGDVLSPTSRA -WLQRWLVETSTGDQRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPPGGAPVLVTCYLTR -SAASAEQRDAAIAQVARAVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Salinisphaera TaxID=180541 RepID=A0A423Q3Q8_9GAMM ---TFRAEIADLEKRHGGRLGLAVLDTAGGQRV-AQRADERFLMCSTFKLPLVGLILSRVD -AGKESLDRHITYDAGDVVTYSPETGQHVGTGMTLGAICRAGLTLSDNTAANLMLRSVGGP -AAVTAFVRALGDTVTRSDRYETALNAYTPGSDRDTTSPSAMGHLMQRLLLDDVLAVPSRE -QLTRWLIANETGDHRLRAGMPGHWRIGDKTGSGGNNTANDIAIVWPQPDAPVIVSAYYAG -SDAGRSQRDRVLADVGRATV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodoferax saidenbachensis TaxID=1484693 RepID=A0A1P8KAH8_9BURK --tQITAALQKLEAQAQGRLGVHLLDTASGQEY-GYRSDERFMMLSSFKLLASALVLARAD -RGQESLERRIRYGRQDLVPWSPVTEAHVDGELTLAQLCHATITTSDNTAANLILASYGGP -QALTAFARQLGDTVTRLDRKEPELNV--RKGILDTTSPRAMAKTLQTLLLGNALSSPSRQ -LLQQWMLANTTGGKRLKAGLPEGWGIGDKTGTNKT-SANDIGILLPPQGAPMVVTAYLAD -SAVSSQRREDAIAEVARVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0005E4932E ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFILAAAVLQRVD -KGELRLMQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF3D85C ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A8CIL3_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI00114284D0 -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5614 TaxID=2690306 RepID=UPI001371FD55 -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0009705505 ------SQFAALERKHGARLGVYVLETGTGASL-AYRADERFAFCSTFKALAAAAVLHQNP ---VSHLGKRVTYTGADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -ARLTAYLRRLGDTVSRMDNYEPELNRDRPRDPRDTTTPRAIAADYQKLVLGEALSAGKRA -LLKDWLVRNTTGAKRVRAGLPKGWTVADKTGTGDYGRANDIAIVWPPHTAPLVMAIMSDR -PGYHTPPKDSLIAEATARIV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TM32 TaxID=1652669 RepID=A0A4Q1RMR6_9ACTN ----AHAALRRLERAHRARVGAFAHNTRTGATV-AYRADTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRVHYTAADVVPNSPVTSQHTVTGMTIAELCAAALQRSDNTAANLLLRALGGP -TAVTDFARSLGDRTTRLDRWEPELNSAEPGRTTDTTTPAAIARTYARLLLGDALTPSDRG -RLTAWMKANETNTERFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPLVLAVLTGT -AQQADPSDDPLVAGVTRVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048D4FE2 ---DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYASTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVAEAAVRYSDNTAGNLLLDHLGGP -ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD -TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T388_9BACT -------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -SDASMEQRNAAIAAIGTALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N6VJX6_9ACTN ---AVDREFRRLETEFDARLGVLAVDTGTGTTV-QHRADERFAYASTFKALAAAMLLDRTS ---ATELDQVVRYSRSDLVAHSPITEQRVATGMRLRDVADAAVRYSDNTAANLMLGHLGGP -DGFERELRRLGDTTTEADRYETALNEGRPGDRRDTTTPRAFATDLRAYAVGDALSQEDRD -VLNGWLRKNTTGDALVRAGVPAGWTVGDKTGGGGYGTRNDIAVLWPPEGAPIVLAVMSSR -DAENAAYDDALIARATRVVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces asterosporus TaxID=285570 RepID=A0A514JTJ7_9ACTN --------LAGLEREYGARLGVFAVDTGSGATV-VHRADERFAFCSTFKTLAAAAVLDRGP ---LDRLERRVTYTRADLAAYSPVTERHVDTGMTLRQLCDAAVRYSDNTAANLLLRHLGGP -RALTTHLRGLGDRVSRLDHYEPELNRNPPGDPRDTTSPRALTADYRALVLDDALPAEKRE -LLRDWLVRNKTGGRRIRAGAPRGWTVGDKTGTGDWGRANDVAVLWPDRGEPIVLAVMSER -PDRAAEPSDALVAEATRRT---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 94 TaxID=2035218 RepID=UPI000C1A92F3 -hrDTHAGLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGSTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=A0A3E1LAW0_XANCA ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPVAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A2A8F241_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKTLREMGDIVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium sp. LK1 TaxID=1628193 RepID=A0A0J6KFW7_9NEIS ----LSRQLAELEHNAGGRIGVAALEVDSGRRV-AYRADERFPMCSTFKLLLVGAVLQLSA -AQPDLLYRHVNYQREQLLRYSPITEQYAEQGMSVKDLCDAAMRFSDNTAANLLLGLLGGP -EAVTRFARALGDGLSRLDRIEPELNSATPGDPRDTTTPAAMVSNLNTLLFSSLLPERQRV -LLRDWLLNSTTGNLRIRAGLPAEWRVGDKTGSGGNGATNDVAVAWRPGKSPLLLAVYYWG -SSALPDERNAVVAAAARVVVAEf ->[subseq from] Beta-lactamase n=1 Tax=Sorangium cellulosum TaxID=56 RepID=A0A2L0EUI2_SORCE ---------------------MAALDTATGARV-GHRAAERFAMCSTFKALLAASLLARVD -QGKLTLDRRVTYRASDLLEHAPVTRAHLAEGLTVEELCAAAVEISDNTAANLLLAQIGGP -AGLTAYIRSLGDQVTRFDRNEPTLNTNVPGDPRDTTSPDAMTDTIRVLLVGDALSEASRA -RLKSWMVRSTTGLARLRAGLPKDWVVGDKTGTGENGAANDVAVAWPPSRAPIVIACFVDA -PSASVDARNAAHAEAARIVAEVf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID14515 TaxID=2706074 RepID=A0A6B2Z2G5_9ACTN -------DFKELERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLRTYS ---VAGLDRRVTYTREDLVANSPVTERHVDTGMTVGELCDASVRYSDNTAANLLFDHVGGP -KGLDSALETIGDRVTRMDREEPDLSRWVPGEKRDTSTPRALAEDLRAFVLGKALEKPERA -QLTTWLRTNTTGAKVIKAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Rubrivivax gelatinosus (strain NBRC 100245 / IL144) TaxID=983917 RepID=I0HQQ0_RUBGI -------AFGAIERSVAGRLGVWAYDLETGRSL-GHRQDERFPMCSSFKWLLAAAVLARVD -RGQERLERRIVFGREALLEYAPATSRRAGGAMTVAELCEAAVTLSDNTAANLLLDTLGGP -AGLTAWVRTLGDRTTRLDRREPDLNEARPGDERDTTTPQAMVLALRQALFGGGLSRRGGD -LLLQWMVASTTGAKRLRAGFPADWRIGDKTGTGAQGTTNDVAVVWAPGRAPLLLAAYLTE -SQAVIEAREAALARVAG------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. f150 TaxID=1827699 RepID=UPI000BF1DEEB -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALPAPERA -QLTTWLRTNTTGDAVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2T0DMP8_9BACI -----RHSFVKLEKEYDAKLGIYALDTDTNQTV-TYRSDERFAYASTHKALAVGTLLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPKRFEPELNEVQPGDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGAYGTRNDIAIIWPPNKKPIVLAILSNH -AKEDAKYDDKLIADATKIVLN-- ->[subseq from] class A beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=UPI00114F7D34 --------LAGLEREYGARLGVFAVDTGSGATV-VHRADERFAFCSTFKTLAAAAVLDRGP ---LDRLERRVTYTRADLAAYSPVTERHVDTGMTLRQLCDAAVRYSDNTAANLLLRHLGGP -RALTTHLRGLGDRVSRLDHYEPELNRNPPGDPRDTTSPRALTADYRALVLDDALPAEKRE -LLRDWLVRNKTGGRRIRAGAPRGWTVGDKTGTGDWGRANDVAVLWPDRGEPIVLAVMSER -PDRAAEPSDALVAEATRRT---- ->[subseq from] class A beta-lactamase n=1 Tax=Verrucosispora sediminis TaxID=547162 RepID=UPI000B852AE2 ------VDFAPLEREFDARLGVYAIDTGSGSTV-THRADERFAYASTFKALAAGAVLAATS ---TEELDQVVSYSRDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP -SGFMQALREVGDEVTEPVRWETELNAYVPGERRDTSTPEALATTLRAYAVDDALSPDDRA -LLVDWLKRNTTGDKTIRAGVPEGWAVGDKTGSADHGTRNDIAVIWPPDRAPIVLAVLSDR -AEPDAERDDALLARATELTLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillales TaxID=1385 RepID=UPI00048C4B97 --------FENLENEYDARLGVYAIDTGSGETI-AYRADERFAYTSTFKALASGAVLMQNS ---VEDIDEMISYSAEDLVTYSPITEKHISTGMTLRDIMDAAIRYSDNTAGNLLLKQLGGP -DGFEAALRQIGDMVIQADRYETELNEAVPGDDRDTSTARALATSLNAFALGDVLPEDKQT -ILTDMLRGNTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDIAIVWPPEGDPIVLAILSSR -DAQDADYDNALIAKAAEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=T1T7P6_9BACT --hSVQKQLAQLESSAGGRLGVAAINTANNQRI-EYRSEERFPLCSTSKVMAVAAILHNSS -TDAKLLATNLRYTQQEVAAYAPIAAKHVATGMTVGAMCQATLNYSDNLAMNELLKELGGT -KAVTAYARKIGDNSFRLDRKEPELNSAIPGDLRDTTTPLAMQNSLQTLVLGNSLAPTQRQ -QLQEWLKNNTTGSARISAGVPKNWLVGDKTGTGKYGTSNDVGVIWPTGAQPIVLAIYFTQ -NKPDAKANDQVIADATRIVVAEf ->[subseq from] class A beta-lactamase n=1 Tax=Thermocrispum municipale TaxID=37926 RepID=UPI0004207B46 --dELASRFRRLENKFAARLGVYAIDTGSGTEV-KYRADERFAYASTFKALAAGAVLARRS ---PADLERKVRFTSDDLVTYSPVTERHVGQGMTVRELIDAAVSYSDNTAGNLLLAELGGP -EGLARALRAIGDRTTHVDRWEPDLNDHTPGDVRDTSTPRALATSLRTYVLGTALPEGRRK -ILVDALIGNTTGDAVIRAGVPHRWTVGDKTGTASHGTRNDIAVLWPPDEAPIVLAVLSDK -RDADADPDDALLAEATKVVL--- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BEBF7B1 ---ATYQEFSQLEKKFDARLGVYAIDTGTNRTI-AYRPNERFAYASTYKALAAGVLLQQNS ---IDKLNEVITYTKEDLVEYSPITEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFEPELNEGTAGYIRDTSTAKAIATNLKAFTVGNALPAHKRN -IFTEWMKGNATGDKLIRAGVPTDWIVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF6F5E7 -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALLTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF2BCD2 -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALLTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CdTB01 TaxID=1725411 RepID=A0A0U3P1H6_9ACTN -------PLTELEREHGARLGVFAHHLRTRRTL-AHRADERFPICSVFKTLAAAAVLRDLD -RHGEVLSRRIHYTRDDLVDGAPVTDEHLAHGMTIAELCDAAVRYSDNSAGNFLLRELGGP -TAITRFARSLGDPVTRLDRWEPELNSAEPGRRTDTTSPRAIGRTNARLLLGDALNPSDRA -LLTHWLLNNTTGGTRIRAGVPGTWAVAEKTGSGSYGTTNDVGVAWTADGDPIVLAVLSTK -PDRDAAWDSTLIASAAGVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000762AF3F ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03234 TaxID=1703937 RepID=A0A1Q5LXG3_9ACTN -------RLRALERRHGARLGAVARNTVTGATV-LYRADERFPMCSTFKTLAAAAVLRDLD -RHGEVLAKRIRYTRDDLVENSDTSEEYLATGMTVAELCWAAICHSDNTAANLLLRELGGP -AAVTRFCRSIGDGTTRLDRWEPELNTCEPWRVEDTTTPAAIAGTYERLVLGTALNRPDRE -RLTGWLLANTTSTYRFRAGLPADWRLADKTGGGAYGTNNDVGVAWTPDGTPVVLAVLTTK -PAQDAPADNPLVRDAASVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzae TaxID=64187 RepID=A0A411XWC9_XANOO ---MLRAQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRDIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDISILWPPKGAPLLLTTYLNG -AKIDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0002299CCE -----DREFAKLEEKYDAHLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALATSLQTYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYATRNDIAILWPPKGDPIVLAILSDR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces acidiscabies TaxID=42234 RepID=A0A0L0JDA4_9ACTN --aATRDVFAGLEQEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLREGV -----DLTRRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP -TAITRFARSLGDPVTRLDRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRT -RLTSWMIANSTNTTRFRAGLPADWILADKTGGGSYGVANDVGVVWPPGRPPLVIAVLTTT -YAAEGPSKNELVARAAELVAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Prauserella sp. PE36 TaxID=1504709 RepID=A0A365Z7V8_9PSEU ---TAEREFGELEQRFDARLGVYAVDTGTGREI-SHRADARFAYCSTFKALATAALLSERT ---IAELDEVVPYTVDDLVTFSPVTEKHAGAGLPLRELMDAAVRYSDNTAGNLLLRELGGP -KGLQAALREVGDQTTHVDRFEPELNEATPGDIRDTSTPRALATTLRAYALGDTLTADKRA -ILIDMLRRNLTGDELVRAGVPDGWVVGDKTGTGGYGTRNDIAVVWPPDRAPIVIAIMSSR -AEQEAEPDNALLAEATKTVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DF7C03 ------DRLRALERAHQAHLGVYARNLRTGATM-THRAGERFGMCSTFKVLAASAVMRDRD -GDGTFLDRIVHYTEADLVENSPITENHVHGGMRIAELCHAAICYSDNTAGNLLLRQIGGP -AGVTRFCRSLGDRVTRLDRWETELNDIAPGDPRDTTTPRAIGENYARLALGTALDPVHRA -RLTGWLIGNTTSAKRFRAGLPDSWLIGDKTGSGAYGSGNDVGIAWTGTGTPLVLAVMTRK -HEPKADYDDELIAEAARICAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ERV7 TaxID=1322334 RepID=A0A197SM95_9ACTN ------ADFKELERKYGARLGVYAVNTGDGREV-AWRDGERFAYASTFKALAAGAVLRKYS ---LDGMTKLITYSKDDLVANSPVTEKHVDTGMTLGELCDAAVRYSDNTAGNLLFDALGGP -KGLERALRETGDTVTRVERREPDLNQWAPGTVRDTTTPRALAKDLRAFVLGDRLGTAERA -QLTRWLRTNTTGGELIRAGVPKGWTVGDKTGAGGYGIRNDIAVVWPPDAAPIVVAILSNR -GTKEADYDNKLIADAAAVAV--- ->[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella zoogloeoides TaxID=352475 RepID=UPI001323ACD4 ----LEKRLADLEARHKGRIGVAIHNLATGVRV-GHRADERFLMCSTFKALLAAHILARVD -RKEEALDRRIVVKKSDLSEWSPVVEKRVGGNISIAELCEAAVTLSDNAAANLLLTASGGP -KALTAFLRGMGDEVTRLDRTEPTLNYETPDDERDTTTPAAMAETLRRLIIGDVLSPRSRA -QLAAWLVMNKTGDTRLRAGLPADWLTGDKTGTNGHGNANDVAIAWSPDRGAVVVTAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus bacterium TaxID=2053512 RepID=A0A3D0E3F1_9BACI ---NIDEKFTQLENEFDARIGVYAIDTGSNQTI-EYRPEERFAFASTYKALAAAILLQQNS ---LEELQEVITYTEDDLVTYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLYEALGGP -KGFEQALREIGDNVTKADRFEPDLNNFTPEDTRDTSTPRALATSLQAFAVSDLLTDDKQE -LFTDWLKGNATGDTLIRAGAPEGWEVGDKSGAGGYGTRNDVAIVWPPNREPIVIAILSRH -NTEDAEYDDTLISQAAEIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium jaguaris TaxID=1312183 RepID=A0A387FUF7_9RHIZ ---DAEKQLADLEKKTGGRLGVSVLDTETNISL-GYREGERFALCSTYKALAVGFVLARVD -QGLEKLDRRVTYGNDAVVTYSPATEKHAGTDMTIAELCGAAITLSDNTAGNLLLDSFGGP -SALTAWLRTTGDTETRLDRKEPDVNQAIKGDPRDTTTPDAMLDTIGLLTLGNTLSETSRD -QLSIWLVNNTTGNARLRADLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTFVGE -ATAPAKDIEAVFAEVGKIIV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR7_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEFCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEAFPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000D07F9CF -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETELNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNDLIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. W1SF4 TaxID=2305220 RepID=A0A3S8Y2K0_9ACTN ---RVARALAALEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD -HDGSVLARRVHYTQADIDRYSEWTKRHLANGLTIAELCEVSITYSDNTAANLLLRELGGP -DAVTRFARSLGDPVTRLDRWEPELNSAEPDRVTDVTTPRAIARTYARLVLGDALGRADRG -LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIVWRPHGAPLVLAVLTTK -PAQDAKADDALVSGAARVLAKAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNH189 TaxID=1136432 RepID=UPI0004670862 -------NLAALEREFGARLGVFAVDTGTGATV-VHRADERFALLSTFKTLAAAAVLERRP ---GARMDERITYGEADLVPYSPVTEKHLATGMTMRQVCDAAVRYSDNTAGNLMLRDLGGP -RALTAYVRGLGDRVTRLDHTEPELNNNPPGDPRDTTTPRVIAADYRALVVGDALPGAGRA -QLTDWLVRNTTGDRRIRAGVPRGWKVGDKTGSGEWGRANDAAVLWPGNGSPLVLSVLTER -PDRDAAAADELVAEATRRVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPY7_9BACT ------------------------------TQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLFNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=A0A542F426_9ACTN ---AAEQEFQRLEKTFQARLGIYAVDTGTGRTV-EHRPDERFAYASTWKALAAAEVLDGTT ---DPELDRVVRYSAQDLVSHAPITEKHVAEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -QGFEKKLRGIGDTVTDPARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD -VLLGWLKGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVVAVLSSR -DKLDATPDDALIAQATTVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Synechococcus sp. BO 8801 TaxID=169670 RepID=UPI000B985402 ----AEVALAALEARSGGRLGVFAIDTASGARI-GHRADERFPLCSTFKAILAGAVLHRSQ -RQPGFLEQRIRFGREDLVTHSPIAEQHLEGGLTVAEMAAATVQYSDNTAANQLMARLGGP -AGLTAFARSTGNRTFRLDRWETALNSAIPGDPRDTDTPSGMGTSFQALVLGSALDLPQRR -RLQDWLIGNTTGDRRVRAGVPPGWRVGDKTGTCGYGTANDVAVLWPPERGPIVLAIFHTQ -VDPAAQAQDGVLAAAATIVAEAf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis potens TaxID=1246458 RepID=UPI00034CFD6E ---AAEKEFKELEKEYDARLGVYAVDTGSEEEI-GYRADERFAFCSTFKALAVGALLDRFP ---DEKLDEVVTYSEEDLVDHSPITEKHVDTGMTLRDISDAAMRYSDNTAANLLFDQFGGP -KGLEAQLGEIGDETTSMDRYETELNSAIPGDERDTSTPRALASDLREYALGDTLKEEERV -FLTDLLKGNTTGDALIRAGVPDDWKVGDRTGGGDYGTRNAIAVLWPSDGDPIVVSILTTR -DDKDAEWQEALVADAAEVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DC5C10E -----DQEFRRLEEQFGARLGIHAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSTRDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD -VLRAWLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DRKDATPDDAVIAQATRVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora sp. DSM 45956 TaxID=2512148 RepID=A0A4Q8ATH7_9ACTN ------EDFERLEREFDASLGVYAVDTATGREL-SYRADERFAYASTHKALTAAAVLRRTS ---LEGLDKRITYDRSDLVAYSPVTKKHVDSGMTLRSVLDAAVRYSDNTAANLMFDELGGP -EGLSAVLREIGDATTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFTVGNALPKDERA -VLNRMLRNVTTGDELIRAGAPDGWRVGDKSGAADYGTRNDIAVLWPPERAPIVLAVLSDR -DAADAEYDNALIARAAEVALRSf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=A0A6C1C6V2_9ACTN ---KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS ---LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP -KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALATDLRAFVLGDVLPGRKRE -VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPITLAIMSRR -DTRDAEHDDALIAEAAEVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429A9T9_9ACTN -----RARLAALERRHGARLGVYALATGTGATL-AHRADERFAFCSTFKALAAAAVLHRNP ---LSHLDDRVTFTRADVDSISPITQHHVATGMTVRELCEAAIRYSDGTAGNLLMRDAGGP -ARLTAFLRGLGDRVSRIDHYEPELNRMGPKNPRDTTTPRAIAADYRALVLGDVLDPAKRA -LLEGWLVRTTTGTARIRAGLPKGWKPAHKTGTGDHGRANDIAVVWPPGVPPLVVAVMSDR -PGYGTPPREALIAEATRVIVA-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. CPCC 101271 TaxID=2656746 RepID=UPI001291A2AF ------PDFAALEAASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFVLCAAVLRQVD -AGRLDLDKRVPMRAEDLIDHAPVTRRHIGKDLTVRDLCRATMITSDNPAANLLLGVVGGP -PAVTRFLREHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFLLGQVLAPASRQ -QLADWLIDNETGDERLRAGLGSTWRVGDKTGSNGKDTTNDIAMLWPMGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAV------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus lentus TaxID=1467 RepID=A0A2X4VYF0_BACLE ---NTDKKFAQLENDFDARLGVYAMDTGSNQTI-EYRPEERFAFTSTYKALAAAIVLKQNT ---MEELKEVIPYTEDDLVSYSPVTDKHVGTGMTLRDIGEAAVRYSDNTAGNLLFKELGGP -KAFEQALRQIGDDITQADRYEPELNAFTPGDPRDTSTPKALATSLEAFVVGDILSDDKRE -LFTDWLRGNATGDTLIRAGSPENWEVGDKSGAGSYGTRNDIAVVFPENREPIVIAIMSRH -DTENAEYDDALIAKVSEVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM44457 TaxID=2508722 RepID=UPI0010099BB8 ----ARRRLRALEREHGARLGAYAYDTGSGRLV-TYRADERFPMCSLFKALNAAAVLRDLD -RDGSFLARRVFYTEQYVKRWSPVTKAHVADGMTIAELCEYSITESDNTAANLLLRELGGP -AAVTRFARSIGDGVTRLDRWEPELNTAEPWRETDTTTPRAIARSYGRLLLGGALAPGDRH -LLTGWMLANRTSGNRFRKGLPADWVLADKTGGGEYGSNNDAGVAWPPGRPPVVLAVMTTK -PEQD-AADDALVAGAAAVLAE-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0011A45AAE --qATHKEFSQLEKKFDARLGVYAIDTGTIQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDLLNEVITYTKEDLVDYSPVTEKYVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAVVWPPNRAPIIIAILSSK -DEKEAIYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Paramesorhizobium deserti TaxID=1494590 RepID=A0A135HNP7_9RHIZ ---KLENELAKLEDRHGGRIGVAILNLATGDKI-GHRADERFLLCSTFKALTAGYILARVD -RGEEELDRRIVHAKKDLVTWSPITEKHVGGAMSVAELCLATVTLSDNTAANLLLNSFGGP -AGLTAFLRSIGDETTRLDRFETELNHEKPGDLRDTTTPAAMLETLRKLLFGDVLSRSSRA -QLAAWMVMNKTGDEKLRAGFPADWMIGDKTGGNGYGNSNDVAVAWSPDRGAVIVSAYCEI -PSVSEKERAAILAEIGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus lentus TaxID=1467 RepID=UPI000DBE18FE ---NTDKKFAQLENDFDARLGVYAMDTGSNQTI-EYRPEERFAFTSTYKALAAAIVLKQNT ---MEELKEVIPYTEDDLVSYSPVTDKHVGTGMTLRDIGEAAVRYSDNTAGNLLFKELGGP -KAFEQALRQIGDDITQADRYEPELNAFTPGDPRDTSTPKALATSLEAFVVGDILSDDKRE -LFTDWLRGNATGDTLIRAGSPENWEVGDKSGAGSYGTRNDIAVVFPENREPIVIAIMSRH -DTENAEYDDALIAKVSEVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas vasicola TaxID=56459 RepID=UPI000531F6D0 ----LRAQWAEIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD -QGKLMLAQRVKIRASDMLEHAPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRSIGDAQTCSDRHEPDMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK -QLTDWMINNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG -AKVEDAARDAALKAVAVAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella cf. planticola B43 TaxID=95610 RepID=UPI0005B261FE ---ILQKKIEMLENKSGGKLGLTVVDTSDGTTY-SWRGDEKFPLCSTSKVMVVAAILKESE -SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP -RHATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMADTLNKLILGTALKKEQKA -KLTEWMKGNTTGLNSIKAGLPAEWKVADKTGSGDYGTTNDIAVIWPKNHAPVILTTYFTQ -PEKDASARKDVLASAAKLIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Sediminibacillus albus TaxID=407036 RepID=A0A1G9A128_9BACI ---DLDEEFSQIEEAFDARLGVYAIDTGTNQSV-KYNPDERFAYSSTFKLLASAFLLKQND ---LKDLEKVVTFVKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLNALGGP -ENYKQALREIGDDVTQPERYETELNEFSPGNKRDTSTPRALANNLRKVVLGDFLPREKQE -LLIDWMKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVIAVMSRH -KTKDAKYDDELVARAAEVTLNAf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A7XH39_9BACI -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILTIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI000997DDA3 ------AELAELERRHGARLGVYARNVRTGRTV-VHRAEERFAMCSTFKAFAAAAVLRDHG --DRAPLDRVVHYPPRDILPNSPRTEENLATGMTVAGLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFLRSLGDTVSRLDRWEPELNTAIPGDVRDTTTPEAIAGSLERLTLGRALRRADRE -RFTGWLKGNTTSAERFRKGLPSAWVVADKTGTGDYATANDIGVAWTTRGTPVVLAVLSDK -SAPDAPVDQALIAEAAAIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS043905 TaxID=2033504 RepID=A0A2C4R755_9BACI ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTNEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Tokpelaia hoelldoblerii TaxID=1902579 RepID=A0A1U9JTU4_9RHIZ ---------KELERQSGGRLGVYVLDSRSKQEF-SYRGDERFAMCSVFKWLLAAAVLARVD -AGQEKLDRIIRFKKADLMEYSPGTKQFVDGPMSIAQLCKTAITISDNTATNLLLDKLQGL -AALNAFLHSKGDNTTRLDRLEPDLNEARPGDERDTTTPEAMGGNLQRFLTGGSLSTSSRK -QLTEWMLATRTSGERLRSGLPSGWRLADKTGTGSNGTANDVGVYWTPTGEPVFVCVFLTE -TSIDRAEQSKVIADIGKKI---- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A097SRP9_9ACTN ---ETLVKVKDAEGQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQAT------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. EN16 TaxID=212773 RepID=UPI0008515809 -----GRAFAALEKEYAARLGVYAVDTGTGRAV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAKPERA -RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BEFAE1F -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDIVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000346D1E1 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA -LLTDLMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8N388_9BACI ------HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=A0A2S6AWN5_9NOCA ------AEFHDLEARLRGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLVPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHFVLDPSVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS026049 TaxID=2033493 RepID=A0A2A8FJ69_9BACI ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF7E141 -----HNSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEGAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Reyranella sp. CPCC 100927 TaxID=2599616 RepID=A0A5C5TEK2_9PROT ----LAGDLAKLEAESGGRLGVAVIDTASGIQV-GHRIDERFLMCSTFKLLAAAAVLARVD -AGKEKLDRRIRFESGDILPYSPATKDRVGGMMSLAELCEAAMVLSDNTAVNLMIATFGGP -PGLTAYVRSLGDTVTRHDRSEPGLNDA--DGVLDTTTPAAMAANIRTLVLGTALSEASRQ -QLTAWMIGNKTGDTRLRAGLPRDWRIGEKTGSGK-GTSNDIGLGWPPGRAPVIMAVYLTG -TSASAERQHATIAGVGRAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. SHU 199 TaxID=1591174 RepID=UPI0003A484A9 ---TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SN1 TaxID=2055158 RepID=A0A2M8T636_9BACI -----IKKFVQLEKKFDARLGVYAIDTGTNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHVDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKANRFETDLNSAVPGDIRDTSTAKVLATDLNAFTVDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIILAILSNR -FTKDAHYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD184 TaxID=1053242 RepID=R8U3R6_BACCE --qETYKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPVEKRK -ILTERMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSK -DEKEATYDNQLIAEATKVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8W4_9BACT ---TLQQKLASFEKMSGTKIGAAAINTADNTYL-QYRATQRFPLCSTFKVMVTAAILQKSM -AESDLLQQKIYYKKQDFVYYSPVTEKHLADGMTVAELSAAAMMMSDNTATNLLLKKLGGP -QAVTAFARSIGDQIFRNDRFEPDMSSSIPGDIRDTSTPLAMASSLRRLVLGDNLGLVQRQ -QLQTWLIGNTTGDKLIRASVPQGWTVGDKSGKGDYGTRNDIAIIWPLHGAPIVMAIYTTQ -SIKDAESRDAVVAGVARILLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI00056497A9 ---QFHDRLLELEKKFDARLGVYALDTEGGATV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVTYARGDLMKHAPVTGQHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -GELTAFARSIGDTVTRMDRIEPAITEATPGDPRDTTTPRAFGTDYQKIVLGDTLTADKRE -FLSDLLRRNVTGAGRIRAGLPGGWTVADKTGTGEYGTMNDFAIVWPPGKAPIVVAIMSSK -AAKDAPYDEALLAEAAKYVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. DUT11 TaxID=1914992 RepID=UPI0010083CD9 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATVRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAESDDALIAGAAKVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF8AEA9 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 8992 TaxID=1591157 RepID=UPI0013717CF9 ---TLQQRLADIERRSGGRLGVSLLD-GSGARLgGQHQDERFPLCSTFKFLLAGAVLQRVD -RGELSLERRVPVRKADLLGNAPVSERHVGGTLSVAELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNDFVAGNPRDTTTPAAMAATMRTLLLGEALQPVSRQ -RLIGWMRDNRTGKDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIIWAPGRTPLLLTAYLNG -ASVDSAARDATLKAVAQAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AR2-1 TaxID=2217816 RepID=UPI0011EE4637 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga palleronii TaxID=65655 RepID=UPI000AAE1403 ---TLQAGLREIEARARGRLGVHIIDTATGREQ-GWRADERFLMLSSFKLLASALVLHRAD -RGEESLERRIRYRAQDLVPWSPVTERHVGGELSLAQLCEATITTSDNTAANLILASYGGP -AALTAYARQLGDTVTRLDRNEPGLNRRADGAPLDTTTPRAMAHTLRTLLLGEALRPASRE -RLGQWLLANTTGGKRLRAGVPADWRVGEKTGTAGD-AANDIGIAWPPQRAPLIVTAYLDD -SATDAATRDAALASVGRLL---- ->[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora mzabensis TaxID=995066 RepID=A0A1G8Y8W1_9ACTN -----HEDFERLEREFDARLGVYAVDTATGREL-SYRGDERFAYASTHKALTAGAVLRQTS ---LEGLDKRITYDRADLVAYSPITKKHVDSGMTLRAVLDAAVRHSDNTAANLMFDELGGP -EGLSAVLREIGDTTTHVDRIEPELNETEPGDIRDTSTPRALATSLRAFTVGNALPKDERA -VLNRMLRNVTTSDELIRAGAPDGWRVGDKSGAADYGTRNDIAVLWPPERAPIVLAVLSDR -DTADAEYDSALIARAAEVAVRSf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus BAG6O-2 TaxID=1053193 RepID=J8ZX71_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDFSNYNPITEKHVDTGMTLKELADASVRYSDSTSHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK333 TaxID=2512158 RepID=A0A4R6NVQ9_9RHIZ ---DADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAQLCGAAITLSDNTAGNLLLDSFGGP -SALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTYVGE -ATAPAKDIEAVFAEVAKIIA--- ->[subseq from] Beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5PRG7_9BURK ---RLEAGIRAVEKRSGGRLGVALLDTGSGALH-GWRLDERFPMCSTFKMAAAALVLKRAE -TGEENLDRIVRFGPADQVAYGPVTEPLLPDGLTVGELAGAIVTFSDNTAANLLLRSFGGP -SALTAWLRTLGDDRTRLDRTEPALNTAIPGDLRDTTTPRAMAMTLQRIALGDALKAPSRA -QLIGWMQASRTGDRKFKAGVPAGWRVAGKTGAGANGTSNEIAVLWPPAGAPLVVCAYLTG -AKVESAARDQVIADVGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. LL01 TaxID=1665556 RepID=A0A0J5JNP0_9BACI ------AEFKDLEKEYDARIGVYALDTGSNKSV-SYRADERFIYASTHKALAVGALLHKKS ---IEDLEELITYTEGDLVNYNPITEKHLGKGMTLKELSDASIRYSDNTAGNLIFNAIGGP -EGFKEVLREIGDNTTEPERIEPDLNNVKPGETRDTSTPKALAESLQAFTLGDALPPEKQN -LLIDWLKNNTTGDALIRAGVPEGWIVGDKTGAGSYGTRNDIAVIWPPKGAPIILAVLSSR -DEADAEYDDALIAKATDEALK-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas cannabis pv. cannabis TaxID=1885894 RepID=A0A0B2CUV9_9XANT ---MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -QGKLTLTQPVKIRAADMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTAFLRSIGDTKTRSDRYEPEMNGFAPGELRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLATYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis potens TaxID=1246458 RepID=UPI00034CAE07 ----VEQAFAELEEEHDARLGVYAVDTGSEEEI-AYQADERFAYCSTFKAMAVGALLREHP ---EEKLDEVVAYSEEDVIGYSPITEKHVDTGMTLRDIGDAAMRYSDNTAGNLLFEQFGGP -KGLQAELREIGDETTSMDRYETELSEAVPGDERDTSTPRALAANLREYALGDSLTDGEQD -YYTDLLERNLTGDALIRAGVPDGWKVGDKTGSGGYGTRNDIAVVHPPDGDPIVIAIMTSR -DEKDAERREALVADAAEVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Weissella cibaria TaxID=137591 RepID=UPI00143F29F4 -----------------------------GKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFWHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sienata TaxID=248552 RepID=UPI0012ECE9D0 ---ATTQQFTDLEAAHGARLGVFALDTADGRSV-AYRDGERFPMASTFKGLACGALLHEHP -LSSGFFDRVIRYPRTDLVDYSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLGGP -AGFTAFLRTLGDDTSRLDRWETELNTAIPGDERDTTTAAALAADYRALVVGDSLVEPERA -QLAAWLVASATGGDRIRAGLPTGWKVGNKTGSPAYGSALDVAIAWPPGRAPLVIAVLTTK -SEQNAEPDNALVASAARAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia higoensis TaxID=228599 RepID=UPI0002F08C98 -------SFAELEANTVARLGVFAVDTGTGRTV-AYREHERFPMASTFKGLACGALLREHP -LSTGYFEQVIHYPATELVEYSPVTEQHVESGMTVAQLCEAAITLSDNTAGNQLLKLLDGP -AGFTAFLRSLGDETSRLDRWETELNSAIPGDERDTTSPAALAADYRALVVGDVLAEPERE -QLSSWLVANTTGDTRIRAGLPDDWTVGDKTGSPAYGSALDVAVAWPPGRAPIVIAVLSAT -TDPGAEADNALIADAARAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A3Q9SIQ1_9BACI ---ATIKKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEELNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGNPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucosispora sp. CNZ293 TaxID=2035249 RepID=A0A2G7D3P8_9ACTN -------DFAPLEREFDARLGVYAIDTGTGRSV-AHRADERFAYASTFKALAAGAVLAATS ---DEELDRVVSYSHDDLVTYSPITERHVDTGLSLRAIADAAVRYSDNTAGNLLLKQLGGP -SGFKQVLREVGDEVTEPARWETELNAYVPGESRDTSSPQALATTLRAYAVDDALSPADRA -VLVDWLKRNTTGDATIRAGVPDGWAVGDKTGSADHGTRNDIAVVWPPDRAPIVLAVLSDR -VEPDAERDDALLARAAEITID-- ->[subseq from] Beta-lactamase (Fragment) n=64 Tax=Bacteria TaxID=2 RepID=A0A0C5B5N5_ECOLX -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E32B45A ----LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFMRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -AAVDAAARDVALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI0010BD8DAD -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea TaxID=53335 RepID=UPI00142DE7E3 --qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMTLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus cereus group TaxID=86661 RepID=A0A657UYB1_9BACI -----RHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A561PDI3_XANCT --qSLAQRLAEIERRTAGRLGVTLLD-GAGTVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELSLEQRVDIRAADMLAHAPVTERHVGGALSVAELCRATMIYSDNPAANLLFPLVGDP -PGLTRFLRGLGDAQTRSDRHEPEMNQFAAGDPRDTTTPAAMAATLRALLLGDVLRPASRQ -RLTEWMIDNRTGDDCLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGGTPLLLTAYLNG -ARVDSAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. IBTA2 TaxID=2283625 RepID=UPI0013F46EA8 ----TDRAFAELERKFDARLGVYVVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAVVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. Ad5 TaxID=989436 RepID=UPI0007AE44C9 ------DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD -RGEESLGDLVTYKATELVSYSPITENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARHGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDAGAPYLASVYMMG -SDASFRQRNAVIAEIGKAMIE-- ->[subseq from] Beta-lactamase n=2 Tax=Pseudovibrio TaxID=258255 RepID=A0A165NXD9_9RHOB ------DTVSQLETEVGGRIGVVLRHTGSDWAV-EHRADERFPMASTFKALLCGAVLSRVD -RGEESLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARHGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDAGAPYLASVYMMG -SDASFRQRNAVIAEIGKAMIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF529FF ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGNPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 5112.2 TaxID=1938848 RepID=A0A2N3XMC7_9ACTN ----VEAELRDLEQRYDARLGVYARNVRTGRTL-SHRAGERFAMCSTFKAFAAAAVLRDRG --DRAPLDRVIHYPPHDILPNSPLTQENLATGMTVGDLCAAAIRYSDNAAGNLLLREIGGP -AGLTRFLRSLGDDVSRLDRWEPELNTAIPGDLRDTTTPRAIGGSLARLGLGRALGDADRE -RFVGWLKGNTTSTGRFRRGLPDGWVLADKTGTGSYATANDIGVAWTTRRTPVVLAVLSTR -STEDATVDEALVAEAARVIAR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6ZY58_KLEPN ------EQIKISEGQLAGRVGYVEMDLASGRMLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTTFLRQIGDNVTRLDRWETELNEALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDQVAGPLIRAVLPAGWFIADKTGAGERGSRGIVALLGPDGKAERIVVIYLRD -TAATMAERNQQIA---------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas albilineans TaxID=29447 RepID=UPI0005F32494 ---ALQQRLAEIERRSGGRLGVCLLDSGTGQRI-GRREQERFPLCSTFKFVLVAAVLQRVD -RGEIGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP -PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLEPASRQ -RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM -ATVDSDARDAALKAVAQAVVAWw ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. MDA0666 TaxID=2135448 RepID=A0A2T2YSK1_9NOCA ------AEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP ---PAELDRRVTYTRADLVPNSPVTEQHVDQGMTVREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAVGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD -VLTGLLRANTTGAALIRAGVPAGWQVGDKTGGGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 1011MAR3C25 TaxID=1675788 RepID=A0A418T7T0_9RHOB ----TLAAVRQAEATLDARAGYASLDLASGRIQ-GYRIDERFPMLSTFKVLVCAAVLARVD -AGEDRLDRHVGYQASQLVEYSPVTEKHVGAGMTLDALCEAAITMSDNTAGNLLLAAVDGP -QGLTDFLRAIGDDTSRLDRWETELNSADPGDPRDTTTPGAMAETLNRLLFGEALSPESRQ -QLLTWMENDRVADALIRAALPQGWYIADKSGAGARGARGIVAALGPDGQPGRIVVVYMTE -TEATLDERNEQIARIGAAIVSDw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BEFC2C1 ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -EGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DvalAA-19 TaxID=1839761 RepID=A0A1C4KVH2_9ACTN ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=UPI0011A4DCDD -------VFSKLEEKYDAKLGIYALDTGTNQTV-NYQSDERFAYTSTHKALAVGALLQQIS ---IEDLNQTITYTRDDLVTYSPITEKHVDTGMTLSEIADASLRYSDNTAGNLILKQLGGP -VGFKESLEEIGDYVTTPERYEPDLNEVNPGEIHDTSTPRALATSLQAFTLGEILPIEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAIIWTPKRDPIVLAVLSSR -DQKDADYNDKLIAEATKQVIK-- ->[subseq from] Beta-lactamase SME-4 n=2 Tax=Serratia marcescens TaxID=615 RepID=Q54488_SERMA ---AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA -IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR -KSKDDKHSDKTIAEASRIAIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ADI92-24 TaxID=1522756 RepID=UPI000F556DC6 ---RTEQAFRTLERKFDARLGVYALDTGSGRTV-THRPDERFAYASTCKALLAGAVLDKNS ---LRQMDRLVRYGRDDLVSASPITEQHVATGLTLRELCDAAIRYSDNAAANLLFHELGSP -RALQDALRALGDNVTRCDRYETALSAATPGDLRDTSTPRALATDLRAYVLGTTLPADKRA -VLTDWLRRNTTGDNTIRAGAPDTWQVGDKTGTGGYGTRNDIAIVWPPGAGPIALAVLSRR -DTKDAERDDALIARAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root708 TaxID=1736592 RepID=A0A0Q8MMD2_9RHIZ --dEIDRRIAALEKQIGGGIGVSVIDTQTNISF-GYRETESFPLCSTFKVLAAGFVLSRVE -KGEENLERRIIYDTDKLVTYSPETGKHVGGDMSVGDLCQAAITLSDNTAANLLLESFGGP -KELTNWLRTFGDASTRLDRWETDLNEAKKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN -TLVEWMVANTTGGARLRSGLPDDWKIGDKTGTGNNGCAADIAIAWPPGHGPLLMTVYVKQ -ASVPVADINPVFAEVGRIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus picturae TaxID=171693 RepID=UPI000E68C72A ---KLDEQFAALEDDFDAQLGVYALDTGSNQTI-AYRAEERYAFSSTYKALAAALLLEQNE ---MEELNEVITYTEDDLVPYSPVTEKHVDSGMTLLEIGEAAVRTSDNTAGNLLFDALGGP -AKFEEALREIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLTDEKRE -LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPPDREPIVMAIMSRH -DTEDADYDDALISEAAEVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWG2_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPVAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ -SDASMEQRNAAIAAIGAALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Roseovarius sp. MCTG156(2b) TaxID=1354722 RepID=UPI00068F5F69 ---ALQQTVQDVEARLGGRIGYAMTDLNSGQDW-GYKADDRFPMSSTFKALLCGVILARVD -AGEESLDRRIAFTADDLVTYSPVTETHVDTGMTVGELCRAAITISDNTAGNLLLATVGGP -RGFTASLRDIGDATTRLDRWETALNESTPGDMQDTTTPRAALATLHALLFGDTLKTASRQ -QLVDWMIADAVADDLLRASLPDGWVIGDKSGAGGHGSRSIIAVIWPSPDHPVLAAIYMTG -NDADMALRNAAIAEIGA------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. HB202 TaxID=767398 RepID=A0A370RN66_9ACTN -------DFKKLERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKEAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albovinaceus TaxID=66867 RepID=UPI000A3C764D -------DFKKLERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKEAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. es.049 TaxID=1761788 RepID=A0A2N0GD88_9GAMM ----ITAELERIEQTLDARIGFAAHNLATSQRW-EVNADERFAMSSTFKTLACGTLLDQAD -KGQLALETEVSFAESDLVTYSPVTEEYAGHQMTLLKLCDATMTTSDNTAANLVLQALGGP -EAVTAFARHMGDPITRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGDVLSDESRQ -QLEEWMKGNAVADGLFRAAIPSDWVIADRTGAGGYGSRSITAIIWPPEQAPTLVVFYITE -TEASFEERNAAIAALGEVI---- ->[subseq from] Beta-lactamase n=1 Tax=Frankia sp. QA3 TaxID=710111 RepID=I9A1A9_9ACTN ---QVRQRLVELERGYPGRIGLAAFAPRTGARV-DYRATERFALASTFKVLTAAAVLRRAR -QEPGLLDRLIRWEAGDVVENSPVTGQHTATGLTVAQLCEAALTHSDNTAGNLLLRQLGGP -AAITAFARALGDPATRLDRWEPELNTNIPGDPRDTTTPAAMASTLRALTFGPALAGQDRD -QLVAWLVANTTGGACIRAGLPAGWRVGDKSGAGVRGMINDVAVAWPPGAGPVVIAIYTTR -TDDHAEGDNRIVADVARLVA--- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 93 TaxID=2135632 RepID=A0A495FCX2_9BURK ---EWNETLANIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDSVTRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR -STAKPEQRDAAIAQVARAVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=UPI00055C730B -------HFAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAAAAVLHRNP ---LSRLDERVTFTKAEVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -AQLTAYLRGLGDTISRMDHYEPDLNRDRPQDPRDTTTPRAIAADYHKLVLGDALAADRRA -LLTDWLERNITGAKRIRAGLPKGWMVADKTGTGDYGRANDIAIVWPPHTAPLVMAVMSDR -SGYNASPRDSLIAETATQIV--- ->[subseq from] class A beta-lactamase n=1 Tax=bacterium SGD-2 TaxID=2713607 RepID=UPI0013ED1896 -------AARQAEKQLDARVGVAIYDTGSGASW-QYRANERFPMTSTFKVLACGALLARAD -NGLEDLNRSVQIRPTDFVAYSPVTEGWSDQQVPLYKLCEATLLTSDNTAANKVLEALGGP -HEVTAFLRSIGDEVTRLDRWETQLNEATPGDARDTTTPAAIATSLRKLVLGDVLSLSAKT -TLTQWLVDNKVGGPLLRAGIPADWQIADRTGAGGHGSRGIVAVVWPPDHAPMTIAVYITQ -TRAAMEQRNEAIASIGSALAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridosporus T7A TaxID=665577 RepID=A0A5J6FUG9_STRVD -------SLADLERAYGARIGVYAVATDTGATV-VHRADERFAFCSTFKSLAAAAVLHRNP ---LSRLDERVTYGRADLAAHSPVTERHVATGMTVRQLCDAAVRYSDNTAANLLLRDLGGP -RGLTTYLRGLGDRVSRLDHYEPELNRNPPGDPRDTTTPRAIAVDHRALVLGDALPAARRA -LLKDWLVRNTTGDRRIRAGVPRGWTVGDKTGTADWGRAHDVAVLWPPRAAPLVLAVLTEH -PDRGAAPSDPLIAEATRRT---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A270ACS9_9BACI ----TIKKFEQLEKEYDARLGVYAIDTGTKKTV-EFNENERFAFTSTHKALAVGALLQQKS ---IEDLNKRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDILPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIADATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ms184 TaxID=1827974 RepID=UPI000BEFE113 -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -NGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A4Q5XFT2_9DELT ---DVHSRFAALEERSAGRLGVAAVDAGTGWRI-GRREGERFPLCSTFKLPLVAAVLRRVD -AGQESLSRVIPYDAGALLEYAPVTREHVAQGLSVEQLCEASVSLSDNTAANLLLETLGGP -AGLTAFFRSLGDETSRLDRNEPTLNTALPADERDTTTPAAMVALLSRILVSSTLSDASRA -RLVDWLVRSPTGRTRLRAGLPRGWRAGDKTGTGENGATNDVAIAWPPGRAPLLICAYSIG -SLQSGDQRAETLAEVARIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Ramlibacter sp. WS9 TaxID=1882741 RepID=A0A4Y7B0Z6_9BURK ------DAWRPLEALSGGRMGVAVLQ-ADGSLQ-GHRLDERFPMCSTFKWLAAAHVLQRVD -RGLDRLDRRIPYGRDALVPHSPVTQEHVGAGMTLGELCHATITTSDNAAANLILATYGGP -QGLTSYARSLGDSVTRLDRWEPVMNEATPGDPRDTTSPRAMAQLLKTALLGDALSVSSRD -QLARWLEACETNGQRLKANLPAGWRMGSKTGTGARGSTNDVGIFWPPGRPPVLVTVYITN -TQAPPADRSGAIAAVARRVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Xenorhabdus mauleonii TaxID=351675 RepID=A0A1I3M8D5_9GAMM ---QIIAQLSALEKSANGRLGAVLIDTADHSTI-TYRANERFPLCSTSKLMVASAVLKQSE -KDESLLNKKVSYPQSALVEYSPITEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLGGP -HKVTEFARTIDDNHFRLDRKEPELNTAEPGDKRDTSTPQAMADSLYNLTLGNALASKQRA -QLVEWLKGNTTGSASIRAGVPADWVVGDKTGRGDYGTTNDIAVIWPDNKSPLILVTYFTQ -PSPEASARPDVLADAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rubrivivax sp. JA1026 TaxID=2710888 RepID=UPI0013E93BED -------AFGAIERSVAGRLGVYAYDLETGRSF-GHRQDERFPMCSTFKWLLAAAVLARVD -RGQERLERRIVFGREALLDYAPTTSRHADGAMTVAELCEAAVVLSDNTAANLLLQTLGGP -AGLTLWVRTLGDRTTRLDRREPDLNEARPGDERDTTTSAAMVLALRQALFGGGLSRRGAD -LLLQWMTASTTGLKRLRAGFPPGWLVADKTGTGAQGTTNDVAVVWAPGRAPLLLAAYLTE -SQAPIEAREAALARVAAR----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NWU49 TaxID=2201153 RepID=A0A2U3GXA9_9ACTN -------SLADLERAYGARIGVYAVATDTGATV-VHRADERFAFCSTFKSLAAAAVLHRNP ---LSRLDERVTYGRADLAAHSPVTERHVATGMTVRQLCDAAVRYSDNTAANLLLRDLGGP -RGLTTYLRGLGDRVSRLDHYEPELNRNPPGDPRDTTTPRAIAVDHRALVLGDALPAARRA -LLKDWLVRNTTGDRRIRAGVPRGWTVGDKTGTADWGRAHDVAVLWPPRAAPLVLAVLTEH -PDRGAAPSDPLIAEATRRT---- ->[subseq from] Beta-lactamase n=1 Tax=Legionella brunensis TaxID=29422 RepID=A0A0W0S039_9GAMM ---SLQGKLAELEASSGGRIGISAINTANDMRL-QYRAEERFPFCSTFKMMGVAAVLKKSM -MVSGLLQQRINYKKEDLIVYSPVTEKHLRDGMTIAELCIAAIQQSDNTAIDLLIKKLGGR -KAINVFAHSIGDLSFRLDRLEPELNSAIPGDVRDTSTPAAMEKSLQRLGLGNGLALPQRE -LLQTWLKGNTTGGARIRASVPKGWIVGDKTGTGDYGTTNDIAIIWPPKCPPIVVAIYFTQ -TKKDAAPNNEVIASATRLLLNTf ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas cucurbitae TaxID=56453 RepID=A0A2S7DSU2_9XANT ----LRAQWADIERGTGGRLGISLLDSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQPVKIRASDMLEHAPVTKRHVGGALSVGDLCRATMIYSDNPAANRLFPLVGGP -PGVTAFLRGIGDAKTRSDRYEPEMNGFAPGEPRDTTTPVAMASTLRTLLLGAALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAVREW- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=A0A2A8HET7_9BACI -----NHSFVKLEKEYDDKLGIYALDTSTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQRIKYTSKDFVNYNPITEKYIDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVQPGDTRDTSTPKALATSLQAYALGDILSIEKRN -FLIDLMKRNTTGDNLIRAGVPGEWEVADKTGSGSYGTRNDIASIWPPNKKPIILAILSNH -AKEDAKYDDKLIADATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-20673 TaxID=1830326 RepID=UPI0009EF1C49 ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F917_9BACT ------------EDQLGARAPYIELDLNSGKILeSFRPEERFPMMSTFKILLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. GW101-3H11 TaxID=1813946 RepID=A0A165JRS1_9BURK ---AWNDALATIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAALAGWMLALVD -QGRERLDARVHYAAADVVAYSPVSGPRAGNALTVGELCAATVSLSDNTAANVLMARHGGP -AGFTAFVRSLGDQVTRLDRTEPTLNEAAVGDPRDTTTPLAMLLTLQKLVLGDALSPASRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTSDSGTANDIGVLWPPGGAPVLVTCYLTR -STAPAEQRDAAIAQVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A0M0G503_9BACI ------ETFANIEDKYDARVGIYAIDTGSDRTI-DYRSEERFAFTSTYKALAAALVLKQNS ---MDELEEVITYTEDDLVSYSPITEKHVETGMTLAELSEAAVRTSDNTAGNLLFEELGGP -EQFQQSLREIGDDVTQSDRYETALNEFTPGNTRDTSTPAALATSLQGFAVGGLLPDDKRE -ILIDWMKGNATGDTLIRAGAPDGWTVADKSGAGRYGTRNDIAVVWAPDREPIIMAIMTRH -DTEDADYDDALIAEVAEVTLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces alboverticillatus TaxID=173770 RepID=UPI000A3B5DD4 ----ICRRLSRLEREHSARVGVFAHNPRTGRTV-RYRADERFPMCSVFKTLAVAAVLRDLD -HDGTFLAKRVHYTQGDVDKWAPVTKDHIADGMTVAALCEATIQQSDNAAANLLLRELGGP -DAVTRFCRSVGDPVTRLDRWEPTLNSAEPWRVEDTTSPRAIGRTYARLVLGDALAPEDRE -RLTKWLLGNTTSTDRFRKALPPGWTLGDKTGAGSYGTNNDVGVAWSPDGSPLVLSVLTTK -HSPDAKGEDALVAETAKLLV--- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T4B4_9BACT -------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VSDEDLKRQVPISQSDLVTYSPVTETWVGQDISLDALCDATLRTSDNTAANKVLEALGGP -DAVTAFMRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLIAAIYLTQ -TDASMEQRNAAIASIGTALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. MUS 060 TaxID=1588031 RepID=UPI0005F2794A ---ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFLLVAAVLQRVD -RGEVGLDQRVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP -PGLTRFLRAHGDTQTRSDRNEPSMNGFALDDPRDTTTPAAMATTMRTLLLGDVLQPASRQ -RLIDWMIDNRTGEDCLRAGLPAGWKIGDKTGNNGSDSRNDIAIVWPPGRAPLLLTAYLNM -ATVDSDARDAALKAVAQAVVAWw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI0004C7D007 ---AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP -KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR -GDKDTPFDNKLIADAASVVTD-- ->[subseq from] BETA-LACTAMASE n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0000112596 -------DFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFAPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDCBCB ---EIDRRIGALEKQIGGRIGVSVIDTETNISF-GYRETETFPMFSTFKVLAAAMVLSRVD -KGEENLERRVVYEKEQLIAYSPEAEKHVGGEMSVGDLCKAAITLSDNTAANLILESLGGP -KELTNWLRTLGDGSTRLDRIEPDLNDIAKDDPRDTTTPDAMLDTLGNIALGSVLSEPSQK -TLIEWLVANTTGNERLRTGLPETWKIGDKTGTGKNGSAADIAICWPPGHGPILIAVYVTN -ATVATAEINPVFGEVGRIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Pseudovibrio sp. WM33 TaxID=1735585 RepID=A0A166F5K1_9RHOB ------DTVGQLETEVGGRIGVVLRHTGSDWTV-EHRADERFPMASTFKALLCGAVLSRVD -RGEENLGDLVTYKATELVSYSPVTENHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARHGDPRDTTSPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPDAGAPYLASVYMMG -SDASFRQRNAVIAEIGKAMIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ766 TaxID=1169157 RepID=UPI0003622F58 ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALDKRDRA -RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / VKM B-512) TaxID=1348623 RepID=A0A5B7WKA7_BACMB ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRA -LLTDLMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. (strain JS42) TaxID=232721 RepID=A1W8B5_ACISJ --qQLQAALGRVERRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD -QGLERLDARVRYGREDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP -AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA -RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ -CPAAPAQRDAAIAEVGSLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces acidiscabies TaxID=42234 RepID=A0A1Q2Z267_9ACTN --aATRDVFAGLEQEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLREGV -----DLTRRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP -TAITRFARSLGDSVTRLDRWEPDLNSAEPWRKTDTTTPHAIARTYAKFLLGDVLPPADRT -RLTSWMVANSTNVTRFRAGLPADWILADKTGGGSYGVANDVGVVWPPGRPPLVIAVLTTT -YAAEGPSKNELVARAAELVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=H9AXL9_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAAHLFLTTIGGP -KELTAFLHNMGDHVTRLDCWGPKLTEAIPHDERDTTMPAAVANTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPILRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Agaribacter marinus TaxID=1431249 RepID=UPI0013AE27BC ---DIKATFSKLEKEFDARLGVFALDTGTNKTI-AYRSEERFAYASTHKALAVGALLQQKS ---MEDLEQRITYTKDDLVNYNPITEKHVDTGMTLKELSDASIRFSDNTAANLIFNQIGGP -SGLKDTLRGLGDEVTNPQRKEPALNEFTPGETADTSTPKALVTSLQAFTLGDVLPEEKRT -ILVDWLKRNTTGDNLIRAGVPSNWEVADKTGAASYGTRNDIAIIWPTKVDPIVLAILSDR -DKEDADYNDKLIAQATKKVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. BK251 TaxID=2512125 RepID=A0A4R1SBX6_9RHIZ ---DVDQQLAELEKRTGGRLGVSVFDTETNITL-GYRETERFAICSTYKALAAALILQKVD -KGEESLERRIVFDKEALVTYSPITEKQTGGEMTLAEVCEAAVTLSDNTAGNLLLESLDGP -QGFTKRLRTIGDASTRLDRTETALNEAKKDDPRDTTTPDAMLDTLGNLAIGTVLSEASRE -RLTGWLVSNRTGDARLRAGIPKEWKVGDKTGTGRNGAAADIAVVWPPGRGPILVTTYVAE -ATVPIDQVNPVFAEVGRIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus polymyxa TaxID=1406 RepID=A0A074LC95_PAEPO ------VVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSFKVLTIDDSMPNDKQE -LLIGWLKENTTGDKLIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDRKPIIIAVMSSR -DTEDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. IBTA2 TaxID=2283625 RepID=UPI00103E5CB6 ----TDRAFAELERKFDARLGVYVVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAVVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Acidisoma TaxID=2634065 RepID=UPI00131A6FC7 ---AMTERLAAIETASDGRLGVAIADMGSGSLL-GYRAAERFPLCSVYKLLAAAAVLALVD -AGKADLDRRIVYGRHAVLDGSPVTLKHIGGKLSLAHLCDAAVTRSDNTAGNLLLSFLGGP -AALTAYIRSIGDDATRVDRGEPDVNQATPGDPKDTTVPAAMLSDLLAFLQGNKLSAPSRA -QLMTWMRGCKTGSGRLEAGLPKGWHIGDKTGSGGYGTTNDVGIVWPSSGAPILVAAFLTD -TTVPAARRNAALAAVGAIV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces globisporus TaxID=1908 RepID=UPI0004C86604 ------GDFKELERKFDARLGVYAIDTGTGHEV-IHNDRGRFAYNSTFKALQAAVVLSTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDGGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDAAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. MB95 TaxID=671602 RepID=UPI0013F6256A ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MMG1522 TaxID=1415545 RepID=A0A0M8T3M7_9ACTN -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLDKYS ---LDGLDRRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Kushneria avicenniae TaxID=402385 RepID=A0A1I1N2L2_9GAMM --kAVQRKLQALEEQHGGRLGVALMNVGTGAVV-SHRGDERFLFNSTGKVFMAAAVLARVD -SGEESLDRRLEIKASDIGEWAPVTEPHVGGPMTLAELCQAAMAWSDNTAANKLIESVGGP -EPITAYLRRIGDDTTRLDRWEPELNTDHEGDERDTTTPLAMMQTLRTLLLGDALSPSSRH -QLAAWMIEGKTGDARLRAGMPPGWLIGEKTGTNSVGNANDVGIAWPADRGAVIAVAYTWL -PKASKTQRDEVIAEIGRLAA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A5Q0DAG0_BACME ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. WMMB 322 TaxID=1286821 RepID=A0A1C6PZZ7_9ACTN ---ATTRRLKKLEREHDARLGVFAHNTGTGTTV-VHRAGERFPMCSTFKPLAAAAVMKARD -GGGSSLDERIRYSRSDLVEHSPVTGTHLAGGMTLRELCDAAVRYSDNTAANLLLRELGGP -TAVTRFCRSLGDEVTRLDRWETELNSAEPGNVKDTTSPRAIGRTYMRLILGDTLGGAGRR -RLADWLKRNTTGEESLRAGLPEGWSVGEKTGAGGYGTHNDVGVAWTAHGEPVVLAVLTTK -KSAGAEPDRALIAKTARILA--- ->[subseq from] Beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=A0A0Q6R8A6_9MICO ---DLDDDLADLEGEYDARVGVYAVDTGSGETV-AYREDERFAYASTFKALLAAVVLKTVD -----DLDRVITYSADELVDYSPVTEQNVDGGMSIRELAEATVRTSDNSAANLLLDELGGP -AGFADALTRVGDRTTQPERRETELNTAVPGETRDTSTPRALAETLRGFALDGLLDDTQAA -TLIDWMSGNATGDPLIRAGAPEGWAVADKSGAGGYGTRNDLGIVWPPDGDPIVIAVLTTR -DAADAEYDNALVADVAAVVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia dabaoshanensis TaxID=564714 RepID=A0A2N7VYI7_9BURK ---AIEAELVSIEKGIGARLGVAIHDIETGLRA-GHRANERFPMCSTFKLMLAASVLARVD -RREESLERRIVFGEDRLETYAPVTRAHTGAPMTIAELCDAAVTMTDSAAANLLLDTIGGP -PGFTAYMRRLGDTVTRLDRTEPTLNTAIAGDARDTTTPLAMLGSMRDVLLGDALSSASRA -QLLAWAVGNRVGDARLRAGVPRDWRVADKTGTGEHGTTNDIGILWPQASAPVLVTVYLTG -TQAPTRAREAAIAGVARTIVRH- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=UPI0013D03A30 ---DVTKRLTRLERSRHARIGAFAIDTGTGRTV-SHRADETFPFASTFKAMACGAVLRKAR -QAPGLLDKVIRYTEADLVDYSPVTEKHVGTGMTVADLCHAAITQSDNTAGNLVLRQIGGP -AGLTAFLRSLGDRVSRSDRWETALNDWRPGERRDTTAPRPWANDLRALTAGNALVPADRE -RLVGWMKATVTGDKRIRAGLPKSWTVGDKTGTGGYGTANDIAIAYPKNGAPLIIVITTNK -RTPDAEADDTAVARTAGILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI00069404FF ------VVFKQLEVKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKLLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTKDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. OK885 TaxID=1882770 RepID=UPI000C70C0FD -hrDTRTRLRELEARHGARIGAFAYNLRTKATV-RHRAAERFPICSVFKTLAAAAVLRDLD -RHGETLARRIHYTVADLAGYSPKTGEHLAGGMTVGELCGAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=UPI00076E4171 ---ELTREFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEDDLVDYSPITEQHVDTGMTLTEVADAAVRHSDNTAANLLFEELGGP -DAFEDALREIGDDVTDPERIETELNAWTPGDTSDTSTPRAMAGSLREFTLGDALPEDRRE -VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVLWPTEGDPIVLAVMSSR -EAEDAEYDDALIARAAEVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura darangshiensis TaxID=705336 RepID=A0A4R5BXM9_9ACTN ---EVTKQIARLEATHHERIGAFAIDTGTGRSV-SHRPDESFPFASTFKAMACGAVLRKAR -EDPGLLDRVIHYTKDDLVDYSPVTEKHVDTGMTVADLCHAGITQSDNTAGNLVLKQIGGP -AGLTAFLRSIGDRVSRSDRWETALNDWKPGEQRDTTAPRPWAGDLRALTVGGVLVPADRK -RLIDWMKATVTGDERIRAGLPKSWTVGDKTGTGGYGTANDIAIAYPKSGAPLIIVITTNK -PAPDADPDDKAIAQTARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000786581B ---AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP -KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR -GDKDTTFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0004B0365B ------SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAANVLARVD -RGEEQLAAMIRYGQADLLEYAPVAREHLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVAGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPSAAQITSAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. Root147 TaxID=1736468 RepID=A0A0Q9GH75_9BACI ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGTLLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLREIADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALATSLQKYVLGQALPEDKRA -LLTDWMKRNTTGDALIREGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas hortorum TaxID=56454 RepID=UPI000BAAB17C -----GARWAEIERGTGGRLGIGLLDSAIGKHF-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -QGLTAFLRGIGDTQTRSDRHEPEMNQFAAGDPRDTTTPAAMALTLRTLLLGDALQPASRK -QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTTYLNG -ASVDSDARDAALKAVAHAVASY- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI0009E25DD6 ------KKLEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AEFKKILEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIADATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12461 TaxID=2014543 RepID=UPI00126556A1 ---TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00096E2B68 ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLMQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPQMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leguminosarum TaxID=384 RepID=UPI000FEC8740 -----------------RSLGVSVLDTETSISF-GYRGSEAFPMCSTFKALAAAFVLARAD -KGEENLDRRVSYGKDKLVDYSPISEKHAGTDMTLAELCEAAVTVSDNTAGNLLLESFGGP -AGLTDWLRSIGDGTTRLDRTEPTLNEGRKGDPRDTTTPDAMLDTLGNLTLGSVLAEASCD -RLIAWLVTSTTGKERLRAGLPADWKVGDKTGTGPNGSLGDIAVIWPPDRGPIVAAVYISE -TTVPVKELNPLFAEVGRMIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=UPI0005C92A77 ---SFESELQELERRYAARLGVYARNARTGQVV-AHRARERFAMCSTFKTVAAAAILRDHA --RCAPLDKVIHYPPADLLANSPRTAEHVDTGMAVGDLCAAAIQYSDNTAANLLLRQIGGP -AGLTRFFRSIGDRESRLDRWETELNDAVPGDLRDTTTPEALGTSYGRLTVGRALDPAARE -HLVTWLKGNTTSGERFRAGLPHDWVVGDKTGTGDYASANDVGVAWTTRQTPIVLAVLTSK -DAKDAPVDNALIADAARIVAR-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A141R9Y8_9BACT --tALTQKLAALEKSTGGRLGVAWID-GDGLRY-GYRADERFPMTSTFKTLAAAAILHNSV -SQPNLLEKKIRIREADRVAWTPVTGNYFGKEMSIAALCAAAIEYSDNLAANYLLKELGGP -QGVTAYARLLGDTLTRLDRQETELNSAAPGDERDTSTPAAMAENLSKLTLGDALPTAQRQ -RLISWLKQNTTGDQSIRAGVPAGWTVGDKTGAGAYGTTNDLAILWPEKGAPKILAIYFTQ -PQPDAANNKAVLASATRLAID-- ->[subseq from] Beta-lactamase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A4Y8U1K3_9BACI ---ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 6-11-2 TaxID=2585753 RepID=A0A4Y4KBY0_9ACTN ----TTARLRALEQGHGARLGVFAHNPATGRTV-RYRADERFPMCSVFKTLAAAAVLRDLD -RHGKVLSRRVHYTEADLVLGSDQTRAHLATGMTIAELADVAIRFSDNTAGNLLLRELGGP -TAVTRFARSLGDPVTRLDRWEPDLNTAEPWRLTDTTSPRAIGRTYARLVLGDALNRDDRR -LLTRWLLNNTTSANRFRAGLPPTWTVADKTGSGAHGTTNDVGVAWTRSGSPVVLAVLSTK -PARDAPYDDALVARTAAAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5643 TaxID=2690307 RepID=UPI00136D5A97 ---SVTARLRELEREHTARLGVYARNMRTGRTV-AHRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTTYSPITEDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALARGDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNHDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8GCG1_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Salinisphaera orenii MK-B5 TaxID=856730 RepID=A0A423PGH8_9GAMM ---AFHAEIADLEKRHGGRLGVAVRDTAGEQRV-AHRADERFLMCSTLKFPLAGLILSRVD -AGEESLDRHITYDAGDVVTYSPETGRHVGTGMTLGAVCRAGLTLSDNTAANLMLRSVGGP -AALTAFVRALGDTVTRSDRYETALNAYTPGSDHDTTSPSAMGHLMQRLLLDDVLSAPSRG -QLTRWLIANETGDHRLRAGMPGHWRIGDKTGSGGNNTANDIAIVWPQPDAPVIVSAYYAG -SDAGRSQRDRVLADVGRATV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. ZEA17I TaxID=2202516 RepID=A0A2V2QMH4_9ACTN ----TDRAFAELERAFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT ---LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAARVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas alkaliantarctica TaxID=232346 RepID=UPI0004AB29E0 ---SITAELGRIEHALDARIGFAAHHLATGQRW-EVNANERFAMSSTFKTLACGALLAQVD -EGQLALDTEVSFEESELVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLVLQALGGP -ESITAFARSMDDPVTRLDRFETELNEATPGDERDTTTPNAMLATLEKLVLGEVLSGESRQ -QLEDWMKGNAVADSLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQVPMVVVFYITE -TEASFDARNAAIASLGKVIQ--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF668C2 ------HSFVKLEKEFDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQIYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S5T8W7_9BACT ------------EDQLGARVRYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVSRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -GQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=A0A2P5JHB5_STRGR -------DFKKLERKFDARLGVYAIDTGTGREV-AHNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIKAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKEAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2B2Z6N2_BACME ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYVSTHKALAVGALLQRKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. GFAJ-1 TaxID=1118153 RepID=H0J5M4_9GAMM ----VRAELQRIEQELEARIGFAAHNFATGQRW-EVNADERFAMSSTFKTLACGALLAQVD -EGQLALDTEVSFAASELVTYSPVTEQYAGQQMTLFELCDATMTTSDNTAANLVLEALGGP -EAVTAFARSMDDSTTRLDRFETELNEATPGDKRDTTTPNAMLATLEKLVLGDVLTPESRQ -QLETWMKGNAVADGLFRAAMP-DWAIADRTGAGGYGSRSITAIIWPPEQAPTVVVFYITE -TEASFEARNAAIASLGEVIQ--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Leaf76 TaxID=1736236 RepID=A0A0S9F4L1_9BURK ---AWNDTLAGIERSAQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPASGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGLTAFVRSLGDGITRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPGSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTTDSGTSNDIAVMWPPGGAPVVVTCYVTA -STASAEQRDAAIAQVARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Soil809 TaxID=1736417 RepID=UPI0006FB88D2 ---DLDDDLADLEGEYDARVGVYAVDTGSGETV-AYREDERFAYASTFKALLAAVVLKTVD -----DLDRVITYSADELVDYSPVTEQNVDGGMSIRELAEATVRTSDNSAANLLLDELGGP -AGFADALTRVGDRTTQPERRETELNTAVPGETRDTSTPRALAETLRGFALDGLLDDTQAA -TLIDWMSGNATGDPLIRAGAPEGWAVADKSGAGGYGTRNDLGIVWPPDGDPIVIAVLTTR -DAADAEYDNALVADVAAVVLE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H4IUV1_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPA-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI00064F9824 ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A651D624_HALSX ----VRKELQRIEQELEARIGFAAHDLATGQRW-EVNADQRFAMSSTFKTLACGALLQRVD -NGQEQLETEVSFSSSDLVTHSPVTEQYADQQMSLFELCEATMTTSDNTAANLVLQALGGP -ETITQFASSLGDPITRLDRWETELNEAQPGDERDTTTPNAMLANLEQLVLGDVLSPDAKR -QLQEWMIGNAVADGLFRAAMPSDWVIADRTGAGGFGSRSITAIIWPPEREPMVVAFYITE -TDASFEDRNAAIASLGRVIQ--- ->[subseq from] class A beta-lactamase n=1 Tax=Kribbella catacumbae TaxID=460086 RepID=UPI00058B82A9 -------AFAVLEKQYSARLGVFALDTGTNRTI-TYRADERFAFASTFKAHACGVLLAQDK -----DLDKLIRYSASDLVANSPITEKHVRTGMTLRQLCDATIRYSDNAAANLILTELGGP -SGFQAGLRKLGDTVTRSDRDEPELSEGKPGDLRDTTTPRALSTTLQKLTLGEALPPAKRA -LLIGWLQTNTTGDKLIRAGAPKTWKIGDKTGSAGYGGRNDVAILWPPNHAPIMLAVMSTK -GVKDAKREDALIAAAAKATL--- ->[subseq from] Beta-lactamase SHV-6 (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=BLA6_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARATTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium FRT-Slr-16 TaxID=1564894 RepID=A0A097SRS7_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQ--------------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Akac8 TaxID=2563106 RepID=A0A4S3GGY5_9ACTN -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDHRP ---GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNGNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRT -LLTDWLVRNTTGDRRIRAAAPRGWRVGDKTGGGEYGRGNDVAVLWPGGRPPLVLSVLTER -PGRAATPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=3 Tax=Stenotrophomonas TaxID=40323 RepID=A0A4S2D9G3_STEMA ------PDFAALEAASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFVLCAAVLRQVD -AGRLDLDKRVPMRAEDLIDHAPVTRRHIGKDLTVRDLCRATMITSDNPAANLLLGVVGGP -PAVTRFLREHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFLLGQVLAPASRQ -QLADWLIDNETGDERLRAGLGSTWRVGDKTGSNGKDTTNDIAMLWPMGGTPWVLTSYLQG -ATVDDAGRNDVLRQVAV------ ->[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI000DEF34BB ----TARQLAELERNAGGRIGVFAQEVDSGRSL-AYRANDRFPMCSTFKLLLVGALLQRSA -TQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEELGGP -QEVNRFARSLGDGLTRLDRIEPELNRAEPDDPRDTTTPAAMTANLHALLFSPLLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLLLSVFYWG -SPAMMDERNAVIAAVARVAAAEf ->[subseq from] class A beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=UPI0004A2E649 ---QLTAAAQQEEKTLNARIGVAVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD -EKKVSLTEAVRFDKSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKVGGP -QGVNAFLRANGDKTTRLDRVEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK -QLTRWMIDDKVADALLRQSLPKGWTIADKTGAGGYGSRSIISMVWPEKGAPLVVAIYITQ -TDASLSQSNAAIARLGHVIFQQ- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=A0A2T2ZEY9_9NOCA ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLVPNSPVTEQHVDQGLTVREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRTIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAITRAATIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF8CB77 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALVSSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGEPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS147 TaxID=2162715 RepID=A0A2T7LH20_9ACTN -------DFKKLERAFDARLGVYAIDTGTGREV-THNDRARFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWAVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAKPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=A0A0M1KKT2_9XANT ---MLRAQWAEIERGTGGRLGIDLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPETNRFAAGDPRDTTTPAAMVATLRTLLLGDALQPSSRQ -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGSDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. Bisph1 TaxID=1274399 RepID=UPI00057BFD8B -----------QEERLGARIGIAVIDTGSGETV-SYRGDERFPMTSTHKALLCGALLSKVD -KGEFTLSDTTQFSQQDLVEYSPVTSKFVAPAMSWQQLCSAAITVSDNTAANVVAKKIGGP -AALTRFVADNGDTVTRLDRAEPELNSAIPGDLRDTTTPLAISHSLQKMALGEILTPASRA -QLVQWMQDDKVADALLRASLPKGWKIGDKTGAGEHGTRSIISIVWPKKGAPRIVSVYVTN -TQATMAQSNDAIARIGKAIFS-- ->[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus dipsosauri TaxID=178340 RepID=A0A317L3B1_9BACI -----DEKFAQLENEFNVQLGVYAMDTGTNQTV-EYRPEERFAYSSTFKPLAAAILLEQNN ---IEDLEKIVTYTKDDLVTYSPVTEKHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -DKFEQALRDIGDDITQPERYETELNEFIPGNNRDTSTPRAMATNLKKVTLDDFLSDDKRE -LLIDWMKGNATGDALIRAGAPEGWIVGDKSGAGSYGTRNDVAIVWPPNREPIVMAIMSRH -DTENAEYDDALIAKAAEITL--- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A0B6X686_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMTVSALLKKSE -TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLDQLGGA -HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT -QLVEWLKGNTTGGTSISAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ -PSKDAKAHNDVLAAAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. f51 TaxID=1827742 RepID=UPI000BF0EAFB -------DFKKLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPGSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVE-- ->[subseq from] Beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A4Z0VRI9_9ACTN ---KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS ---LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP -KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALVTDLRAFVLGDVLPGRKRE -VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPITLAIMSRR -DTRDAEHDDALIAEAAEVAL--- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. feltiae Moldova TaxID=1398200 RepID=A0A077NUE4_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSII-TYRGHERFPLCSTSKMMTVSALLKKSE -TDKDLLNQRIHYQQSDIVEYSPITEKHLKDGMTLAELSAATIQYSDNTAMNLLLDQLGGA -HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT -QLVEWLKGNTTGGTSISAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ -PSKDAKAHNDVLAAAARIMTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=A0A1C3URT4_9BRAD ------SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD -RGEEQLAAMIRYGQADLLEYAPVAREHLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVAGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPSAAQITSAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=UPI0011A192D1 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=A0A0M3QKW1_9ACTN ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI001369A71B ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVDTGMTLRELCDATIRYSDNAAANILFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000D02B67A -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAYTLDNTLTSDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces violaceusniger (strain Tu 4113) TaxID=653045 RepID=G2P477_STRV4 ------GEFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVIKYSEDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -KGLDATLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGDGERA -QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVVAIMSNR -GDKDATSDDKLIADAAHVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium dankookense TaxID=560405 RepID=A0A564FTZ7_9RHIZ --eDAQARLLALARGFSGRLGVAARDTGSGRGL-AHAADERFPLCSTFKLLAAAALLARVE -RGTETLSRAMPYTAADLDSYAPVARRRLEAGMPLGEACAAALVWSDNTATNLVLRALGGP -EALTAWLRQIGDAKTRLDRWEPELNTAIPGDPRDTTTPAAMLATLELVLLGPVLTPESRA -RLAGWMMESRTGLKRLRAGIPATWTVGDKTGSGANGTANVVAIVRPPGRAPLLAAVYITQ -TDAPEAVRDSIHAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI0007EB009C ----VNVVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -KGFEKAMRDNGDTVVMANRYETELNEANPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTKDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. gb14 TaxID=1827753 RepID=UPI000BF13935 -------DFKQLERKFDARLGVYAIDTGTGREV-THNDRGRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVANSPVTEKHIDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -EGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAGDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAASVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A242ZD07_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNELQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Janthinobacterium sp. 1_2014MBL_MicDiv TaxID=1644131 RepID=A0A1I9Y1G5_9BURK ---TAETQLAALEQAAGGRLGVAAWRHGSDVRV-AHRADERFPLASTFKAMLAAAVLARSV -SQPGLLEQHVRYEKKELVTYSPITEKHLADGMSVAKLCAATLQYSDNSAANFLMKILGGP -QAVTAYARSIGNTLFQLERWETELNSAIPGEVRDTASPASMAHSLQQVLLGNSLPAPQRQ -QLDAWMRGNTTGDKRIRAGVPAGWHVADKTGSGAYGSVNDIGVAYPASGAPLLIAVYYTR -EQKNAPTNQDIITAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia cerradoensis TaxID=85688 RepID=A0A231HCU7_9NOCA -----LAEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP ---PAELDRRVTYTRADLLPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDSTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD -VLTGLLRANTTGAALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12460 TaxID=1591132 RepID=UPI00126411F4 ---TLQLQLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGGTLSVAELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDASTQLDRNEPGMNEFVAGDPRDTTTPAAMAGTMRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Dyella sp. LLH-Slr-21 TaxID=1564813 RepID=A0A097SRR1_9GAMM ---ETLVKVKDAEDQWGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRLHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQAT------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Nitratireductor soli TaxID=1670619 RepID=UPI000B3D76A4 --dALARKLVEMEKRLGARLGASITDTHTGRRW-LQRADERFPMNSTFKAFACAAVLARVD -AGEETLEREIAIRKSDLVNYSPVTEKRVGGRMKLFELCEAASTMSDNTAANLLVDSLGGP -QGWTRFMRSIGDGVSRLDRKEPGLTTATPGDPRDTTTPEAIAASLRTLVFGDVLASASRR -QFETWLIDNKVSRPLLRAGLPGDWRIADRTGAGGHGSRGIVAVIWPPARQPVIAAIYIAE -CKQPMDQRNAAIAEIGRTLAE-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A024P8A8_9BACI ---NASEKFSQLENEYNARLGVYAIDTGSNQTI-GYRPEERFAFTSTYKALAAAIVLQQST ---MKELKEVITYTEDDLVSYSPITEKHVDTGMTLLKLAEAAVRSSDNTAGNLLFKGLGGP -DGFEQALRQIGDNTTQSERYEPDLNEFTPGDNRDTSTPKALTTDLQAFAVGDLLSDDERE -RFTNWLQGNATGDTLIRAGAPEGWKVGDKSGAGSYGTRNDIAVVWPPNREPIIISIMSRH -YTEEAKYDDALIAQAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonosporaceae bacterium KJ-029 TaxID=2494575 RepID=UPI0010F9F9D2 -------DFAPLEREFDARLGVYAVDTGTGRTV-AHRPDERFAYASTFKALAAAAVLDVTS ---AAELDQVVTYTRDELVSHSPITGKHVESGMTLRAIADAAVRYSDNTAGNLLLSRLGGP -AGLKQRLRDIGDEVTEPARLEVELNAAVPGDVRDTSTPRALATSLRAYAVDDALSSEDRA -VLVDWLKRNTTGDKLIRAGSPDGWEVGDKTGAGGYGTRNDIAVLWPPDRPPIVLAVLSSR -DEKDAEPDDSLVARAAELTL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000D042816 -----NQSFAKLEKEYDAKLGIYALDTDTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKLE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces pseudovenezuelae TaxID=67350 RepID=A0A101NCV5_9ACTN ---DVTARLRALEERYDARLGVFAHRLSTGRSV-RYRADELFPMCSVFKALAAAAVLRDLD -RHGEVLARRIHYTADDLVMGSDRTKEHLAEGMTIAELADVAITYSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAVGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDAGDPIVLSVLSTM -PAQDAVRDDALVADAARAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=UPI0009E9030D ---DLDDDLADLEGEYDARVGVYAVDTGSGETV-AYREDERFAYASTFKALLAAVVLKTVD -----DLDRVITYSADELVDYSPVTEQNVDGGMSIRELAEATVRTSDNSAANLLLDELGGP -AGFADALTRVGDRTTQPERRETELNTAVPGETRDTSTPRALAETLRGFALDGLLDDTQAA -TLIDWMSGNATGDPLIRAGAPEGWAVADKSGAGGYGTRNDLGIVWPPDGDPIVIAVLTTR -DAADAEYDNALVADVAAVVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=A0A495WZ95_9PSEU ------PALTALEQKYGARLGVYALATGSGTTI-AHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDAVVTYTEQDLMKSSSITRQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTAFTRTLGDQVTRMDRVEPDITEATPGDPRDTTSPRAIGTDYQKLVLGDALEPDKRA -FLTDLMTRNTTGNRRIRAGVPTTWTVADKTGTGDYGTLNDIAITWPPGTAPLVIALMSDK -PTADARYDEALLAEAATYVAE-- ->[subseq from] RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000DE70C44 ----VLEAVTNAETELGARIGLAVHDLETGKRW-EHKSNERFTLSSTFKTLACANVLQRVD -LGKERIDRVVRFSESNLVTYSPVTEKHVGKKMSLAELCQATLSTSDNSAANFILQAIGGP -KALTKFLRSIGDDTTRLDRWETELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQ -QLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITE -TDASFEERNAVIAKIGEQIAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia cerradoensis TaxID=85688 RepID=UPI0005851FCA -----LAEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP ---PAELDRRVTYTRADLLPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDSTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD -VLTGLLRANTTGAALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Pleomorphomonas diazotrophica TaxID=1166257 RepID=A0A1I4W7A1_9RHIZ ----ADDELAALEKRSGGRLGVAALDKATGARL-VHRADERFAMCSTFKFVAAAAVLAAVD -QGKLRLDKSISYGKADLQDYAPVAKEHVAEGLSLEVLCRAAVEMSDNTAANLILKEIGGP -AGWTAYVRALGDATSRLDRTEPSLNTADEGDERDTTTPEAMMGTLDALMVGNALSETSRK -KLEEWMLTGIVTGPLIRAGVPKTWQVADKSGSGGHGTRNDVGIIYRPEKAPILASIYFTG -SDLDMPGRNKVIADTAAIIAARf ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=UPI000EB4C608 ------PALTALEQKYGARLGVYALATGSGTTI-AHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDAVVTYTEQDLMKSSSITRQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTAFTRTLGDQVTRMDRVEPDITEATPGDPRDTTSPRAIGTDYQKLVLGDALEPDKRA -FLTDLMTRNTTGNRRIRAGVPTTWTVADKTGTGDYGTLNDIAITWPPGTAPLVIALMSDK -PTADARYDEALLAEAATYVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0007ABBF20 ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF574A2 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALVSSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=C8CE56_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGGNIKAERIVVIYLRD -TPASMAERNQ------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WAC01526 TaxID=2588709 RepID=UPI0011E06015 ---RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST ---DDELNRVIRYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP -AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTQVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR -GSKDAASDDALIKDATKT----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0107 TaxID=1703942 RepID=A0A1Q5L8F0_9ACTN ----VTARLRDLERRYDAKLGVYAHNLGTGKTV-RHHADDLFPICSVFKTLAAAAVLRDLD -HDGEVLARRIHYTEADLVEGSDETRKHLAEGMTIAELCDVTIRYSDNAAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPRHDRA -LLTRWLLNNTTSDDRLRAGVPSTWTVADKTGGGSYGTNNNVGIAWTPDGTPVVLAVLSRK -SDPDAVRVNALIADTAKVLT--- ->[subseq from] Beta-lactamase n=1 Tax=Diaphorobacter nitroreducens TaxID=164759 RepID=A0A3N1YRQ8_9BURK --qQLQAALGRMEQRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD -QGLERLDARVRYGRQDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP -AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA -RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ -CPAAPAQRDAAIAEVGSLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5HTV5_9ACTN ---AAEQEFQRLEKTFQARLGIYAVDTGTGRTV-EHRPDERFAYASTWKALAAAEVLDGTT ---DAELDRVVRYSAQDLVSHAPITEKHVAEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -QGFEKKLRGIGDTVTDPARYETALNEATPGDRRDTSTARALAGDLRAYTVGDALTPADRD -VLRGWLKGNTTGAGLVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVVAVLSSR -DKLDATPDDALIAQATTVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF22259 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYIGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=A0A0J8VSC3_9ENTR ---QLTAAAQQEEKTLNARIGVAVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD -EKKVSLTEAVRFDQSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKVGGP -QGVNAFLRANGDKTTRLDRVEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK -QLTRWMIDDKVADALLRQSLPKGWTIADKTGAGGYGSRSIISMVWPEKGAPLVVAIYITQ -TDASLSQSNAAIARLGHVIFQQ- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Xanthomonas TaxID=2643310 RepID=UPI001370D40C ---TLKQRLAEIERRSGGRLGVSLLD-GSGAVLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELTLERRLPVRKADLLGNSPVSERHVGGTLSAAELCRAAMIYSDNAAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNDFVAGDPRDTTTPAAMAATMRTLLLGEALQPVSRQ -RLIGWMRDNRTGKDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -AKVDSAARDAALKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00051DEC39 ---MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium frigidicarnis TaxID=84698 RepID=A0A1I0V3J8_9CLOT ---QYNSSFSQLESDYGVKLGVYAFDTETNKEV-VYRADDRFAYCSTFKALAAGAVLKQAS ---LEQLKQVVKYNKEDVLSYAPITKDNVDKGMTIEEICNAALRFSDNTAANLLFDHVGGP -NGFKSALNQLGDNVTQPTRIEPDLNEAIPEDIRDTSTPRQLATDLQAYTTGDILTDDKKK -ILIDWMTGNATGNTLIRAGAPEGWVVADKSGTGSYGTRNDIAIVMPPNKKPIIIAILSTH -DTKEAKHDDKLIAQASKIVFDSf ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00141A9972 ---MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. RP1137 TaxID=1380110 RepID=UPI00042964BF ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLEQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTARALATSLQTYVLGQALPENKRA -LLTDWMKRNTTGNALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429FN01_9PSEU ---QFHDRLLELEKKFDARLGVYAIDTGGGATI-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVEYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTVGNLLLRDLGGP -AELTAFTRSLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD -FLRDLFERNTTGAQRIRAGLPSGWTVADKTGTGDYGTLNDIAVVWPPDKAPLVVAIMSSK -AAKDAPYDQALLAEAAKYVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio neptunius TaxID=170651 RepID=A0A0F4P6E5_9VIBR --dTLTQQVAQLETQSGGRLGVAVLDTQNNHQW-QYRGDERFPMMSTFKALMCASALDLAD -QNKLSLNDTTTIKESDLVTWSPVTEKLIGQDMTIQQACEATMLMSDNTAANIVLHQIGGP -QQVTQFVRTLDDKVTRLDRFEPELNQATPGDKRDTTSPHAMVTSLNTILLQDGLSEKNQQ -TLLTWMKNNKISDSLIRSILPQGWSIADRTGAGEQGSRAINALVWNEQHKPIIISLYLTH -TELDIAQRNQTLNQVAKLVLEHf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. SEMIA4064 TaxID=2127048 RepID=A0A2T3GT50_9RHIZ ---DADKQLADLEKKTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDVVVTYSPETEKHAGTDMTIAELCGAAIMLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVIWPTDRGPILVTTYVGE -ATAPAKDIEAVFAEVGKIIA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229RD96_9PSEU ---QFHDRLLALEKKFDARLGVYALDTAGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRISYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -AELTAFTRGLGDTVTRMDRIEPLITEATPGDPRDTTTPRAFGTDYQRILLGDTLETDKRD -FLRDLLQRNATGAERIRAGLPPGWTIADKTGTGDYGTLNDIAVVWPPGKPPIVMAVMSSK -AAKDAPYDQALLAETAKYVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. DJ TaxID=2067551 RepID=A0A2N5XG17_9ACTN ------RELEDLERKFDARLGVYAVDTGTGREV-AHNDGERFPYASTFKALAAGAVLDKHS ---LKGMDKVVTYSRDDLVAHSPVTEKHVGTGMTLDELCEAAVRFSDNTAANLLLDELGGP -RGLDAVLEEIGDDVTRAERREPELSRWVPGETRDTTTPRALAGDLRAFVLGDVLGKDERA -RLTKWLRTNVTGDDLIRAGVPGDWVVGDKTGTGSYGARNDIAVVWRPGAAPVVMAIMSNR -KERGAEPDDRLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZS1_9BACT --qDLQATVSAWEERLDARIGVVLRDASSDWEI-AMRADERFPMSSTFKSLLCGAVLARVD -AGQENLDRRITYTADDLVTYSPVTEEHLDDGLTVSELCEATVTLSDNTAGNLLLEAVGGP -EGLTTFLRGIGDETTRLDRWETALNEGAVGDPRDTSTPSAILNTLETLLLGDVLTPASAA -QLRQWMIDDAVADTLIRAHLPDGWVIGDKTGAGGNGSRAIIAFIQPEAGVHYFAAIYITE -SDADFALRNQVVSEIGQAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella albertanoniae TaxID=1266829 RepID=A0A4R4PJB6_9ACTN ------ARFQELEKQYAARLGVFAVDTGSRRTV-SYRADERFAFASTVKSLACGVLLRQAK -----DLDKLIRYTAADLVTYSPITEKHVDTGLTLYQLCDAAIRYSDNTAANLILVELGGP -AGLQRALRKLGDGITNVNRNEPTLNEATPGDRRDTTTPCQLATSLQKFTLGHALPPAKRA -ILNNWLLTNTTGDKTIRAGVPKDWKVGDKTGTAGYGGRNDVAVIWPPNRAPIMLAIMSTK -GVKDAPTDDALIAAAAAAAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2B5J6R8_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKYDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces thermocarboxydus TaxID=59299 RepID=UPI0010C0DF18 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDHRP ---GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNGNPPGDPRDTTTPRAIAADYRALVLGDALPAAGRT -MLTDWLVRNTTGDRRIRAAAPRGWRVGDKTGGGEYGRGNDVAVLWPGGRPPLVLSVLTER -PGRAATPSDELVAEAARRVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia tenerifensis TaxID=228006 RepID=UPI000594468B ------RSFTDLETKAGARLGVYAIDTGTGRSV-AYREGERFPIASTFKGIACGALLREHP -IASGFFDQVIHYSRTDLVDNSPETEKHVDTGMTVAELCKAAITLSDNTAGNQILKLLGGP -EGFTAFVRSLGDTSTRLDRWETELNTAVPGDERDTTVPAALAADYRALIVGDVLSDPERA -QLKTWLLANTTGGKRIRAGLPTDWAVGDKTGTPAYGAALDVAVAWPPNHAPIVIAVLSSK -SEQRAEPDNALIADATRTAIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1B1DD ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKYDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI00111F48B4 --qTLQKKIEMLENKSGGKLGLTVVDTSDGTMY-SWRGDEKFPLCSTSKVMVVAAILKKSE -SNTNLLAKKITINKSDMVNYNPITSKYIDSSMTITELSKAALQYSDNAAMNKLLSYLGGP -RYATQFARTIGDKAYRLDRNEPGLNTAIPGDSRDTTTPSAMAETLNKLILGNALKKEQKA -KLTEWMKGNTTGLNSIKAGLPAEWIVADKTGSGDYGTTNDVAVIWPKNHAPVILTTYFTQ -PEKDASARKDVLASAAKLIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT371 TaxID=1136433 RepID=UPI00047FAD54 ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ERELDRVVTYSADDLIAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEALGDDVTRMVRDEPELSRWKPDDTRDTSTPRALAEDLRALVLDDALGKRDRA -RLTEWLRTNTTGDTLIRAGVPGNWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. L2 TaxID=2162665 RepID=UPI001010BD74 -----DDALLDLEQNYGARLGVYARNVRTGDTV-SYRAGERFAMCSTFKTFASAAVLRDHA --DCAPLDRVIHYPQRDILDNSPKTAEHVDAGMAVGDLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFMRSIGDEVTRLDRWETDLNSAIPGDLRDTTTPEAVGRSLEEVALGRVLAPADRE -QLLTWLKGNTTSAKRFRKGLPQDWTVADKTGTGDYASANDIGIAWTTRKTPLVLAVLSAK -PAKKAPVDDDLIAEAARLAA--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. JS23 TaxID=1770053 RepID=A0A1H2PMW4_9BURK ---SVAAEFARIEAATGGRLGVAVEDTASGRRL-AYRGGERFPMCSTAKLLVCGAVLQRVD -AGRDTLDRLVSFAPSALVTYSPATQPHAGTDMTLEALCVAAMTLSDNTAANLLIASVGGP -RGVTALARSLGDTVTRLDRNETTLNEAKPGDPRDTTSPIAMSSNVKALLYGTALSAPSRQ -RLLGWMNGNITGGAKLRAGVPGNWQVADKTGSGGHGTSNDVAVLIPPGTAPWPIAVYLTG -AVIDESARSAAIAAVARAVVRAw ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. UNC305MFCol5.2 TaxID=1449076 RepID=UPI0004A70043 ---EFRKAVLAVEQASGGRLGLAVTDTGSGERF-GWRADDRFPMCSTFKFALAALILKQVE -RKRETLARQIPVAQADIVSNSPFSEKRVGGSASVAELCHATITVSDNSAANLLLRTIGGP -AGFTKWLRSAGDPATRLDRWETEMSEAKPGDVRDTTTPVAMAGLARHLLLGDALTPVSRT -QLTDWMKDTRTSRNSLRAGLPADWAVADKTGAGGYGTDNLVAVLWPPRRPPLVVASYITG -STLEFEKRRPLHAGIGRAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1N6KQG6_9BURK ---SVEGQLAKLEQTAGGRLGVSALNTANGTWI-GHRADERFPFCSTFKVILSGAILARST -QAAGFMQQRIHYAQSDVVHYSAVTAEHIGDGMTVAELCAAAIQHSDNTAANLLIKLLGGT -DAVTAYARLIGNDVFRLDRLETSLNDAVPGDPRDTATPASMVRSLHTLTLGDTLPIAQRT -QLLDWLRGNQMGSKRIGAALPAGWTMGDKTGTGDYGTANDLAVIWPPSRPPLILGIYHTQ -PGQDAKARDDVVAAAARIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. AP09 TaxID=2135476 RepID=A0A395KTF2_9RHIZ ------PKIRRIEAKSGGRLGVACRIAGTTVQF-GYRENELFPMCSTFKALAAALILHRVD -DGIEQLDRSIEVPHDAIIANSPTTKKFAGGAMTVAQLCEAAVTVSDNGAANLLLSSFGGP -PQLTAYLRSIGDTVTRLDRIEPELNESIPGDARDTTSPLAMIDDYERLTLGDSLSHKSRA -QLVDWLVANKTGDDRIRAGLPKGWKCGDKTGTGAHGSTNDAAVIWPASGNPILMSVYLTG -TKQSLAKRNAVIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-118 TaxID=1463881 RepID=UPI0004C80E25 ------RELRELERRFGARLGVHAVDTGTGREV-AYNDGLRFPYASTFKALAAGAVLRKYT ---VGGMGERVTYSRDELVEPSPVTEKHVATGMTLDALCEAAVRFSDNTAANLLLDRLDGP -KGLDAVLEGIGDDVTRMERREPELSRWVPGDTRDTTTPRALARDLRAFVLGDVLGPAERA -RLTEWLKTNVTGDELIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPDGAPIVMAIMSNR -GEKDAEHDNRLIAQAASVVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia tenerifensis TaxID=228006 RepID=A0A318KCJ4_9NOCA ------RSFTDLETKAGARLGVYAIDTGTGRSV-AYREGERFPIASTFKGIACGALLREHP -IASGFFDQVIHYSRTDLVDNSPETEKHVDTGMTVAELCKAAITLSDNTAGNQILKLLGGP -EGFTAFVRSLGDTSTRLDRWETELNTAVPGDERDTTVPAALAADYRALIVGDVLSDPERA -QLKTWLLANTTGGKRIRAGLPTDWAVGDKTGTPAYGAALDVAVAWPPNHAPIVIAVLSSK -SEQRAEPDNALIADATRTAIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. SHU 308 TaxID=1591201 RepID=UPI00039A65E3 ---TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Psychrobacter sp. PAMC 21119 TaxID=1112209 RepID=UPI000288271E ---SLVDAVKSAENELGARIGLAVHDLETEQRW-EYRSDERFPLSSTFKTLACANVLHNVD -IGQEKIDRVVRFSKSNLVTYSPVTEKHVGKKMSLGELCQATLSTSDNSAANFILQAIGGP -KSLTQFLRASGDNTTRLDRWETELNEAIPKDKRDTTTPIAMITTLEKFVVGDTLSTESRQ -QLQSWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPGRKPVIAALYITE -TDASFEDRDAMIAKIGTEIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora righensis TaxID=995060 RepID=A0A1I7C3I4_9ACTN ------EDFERLEREFDVSLGVYAVDTATGREL-SYRADERFAYASTHKALTAAAVLRRTS ---LEGLDKRITYDRSDLVAYSPVTKKHVDSGMTLRSVLDAAVRYSDNTAANLMFDELGGP -EGLSAVLREIGDATTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFTVGNALPKDERA -VLNRMLRNVTTGDELIRAGAPDGWRVGDKSGAADYGTRNDIAVLWPPKRAPIVLAVLSDR -DAADAEYDNALIARAAEVALRSf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus horneckiae TaxID=549687 RepID=A0A2N0ZLR3_9BACI -----AEKFGKLEEEFDARLGVFALDTGTNQTV-EYRSDDRFAYASTHKALAVGALLQQKS ---IEELNERITYNHDDLVEYSPITEKNIDKGMTLKELSDASIRYSDNTAANLILKELGGP -DGFKKSLREIGDAVTNPERFEPELNDVKPGEIQDTSTPKAMAESLKAYVIEDTLPEEKRA -ILTDWLKRNTTGDALIRAGVPKGWEVGDKTGAASYGTRNDIAVIWPPKGEPIVLAILSSR -DKKDAETDDKLIAEATKEVIN-- ->[subseq from] Putative beta-lactamase class a protein n=1 Tax=Xanthomonas albilineans (strain GPE PC73 / CFBP 7063) TaxID=380358 RepID=D2UF46_XANAP ---ALQQRLAEIERRSGGRLGIYLLDSGTGQRI-GRREQERFPLCSTFKFVLVVAVLQRVD -RGEIGLDQQVRVRAADVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP -PGLTRFLRAHGDTQTRSDRNEPSMNAFALDDPRDTTTPAAMASTMRTLLLGDVLQPASRQ -RLIDWMIDNRTGDDCLRAGLPAGWRIGDKTGNNGTDSRNDIAIVWPPGRAPLLLTAYLNM -ATVDSDARDAALKAVAQAVVAWw ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0009E53A72 ---ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEELNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Psychrobacter TaxID=196806 RepID=A0A2I0GIF9_9GAMM ------DSVKNAENKLGARIGMAVHDLETEQRW-EYRADERFPLSSTFKTLACANVLHNVD -LGQEKIDRVIRFSKRNLVTYSPVTEKQVGKKMSLGELCHATLSTSDNSAANFILQAIGGP -KSLTHFLRSIGDNTTRLDRWETELNEATPKDKRDTTTPMAMITTLEKLVVGETLSTESRQ -QLQSWLKANEVGDALFRKGVPSDWIIADRTGAGGYGSRAITAVMWPPGRKPIIAALYITD -TDASFEDRNAVIAKIGIEI---- ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora inagensis TaxID=103730 RepID=UPI0004171BD2 -----GTDLAELEAAHGARLGVWGRNTRTGRTV-EYRAGERFPMCSTFKTVAAGAVLRDRF ----SPLDRVIHYPPSDLVPNSPITGEHVDTGLSIGDICAAAIQYSDNTAGNLMLRQIGGP -PGLTGFFRAIGDQTSRLDRWETELNTAIPGDPRDTTTPAALGRDYERLTLGDALSHPDRE -RLVTWLKGNTTSAARFHKGLPATWTIADKTGTGDYATAHDIGVVWTGHGTPLVLAVLTTK -STKDAPADDDLIAEAARLAAN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. OK228 TaxID=1882786 RepID=A0A2C8X962_9ACTN ---------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylophaga sp. TaxID=2024840 RepID=A0A2E2D8T8_9GAMM ----WQTTFAQLEKEYGGRLGIAAYDLQHQFQL-HYRANERFALCSTFKVLLVANVLHRID -QHQESLSRPIHYDRADILDYAPVTKTHLDEGMSVAALSQATLQLSDNTAANLLLKTIGGP -EALTDYLRSIGDNTTRLDRIEPALNSNLAGDLRDTTTPAAMLATLNTLLLGDHLSDVSKQ -RLIQWLIGNQTGDDKIRAGVPSTWLVGDKTGSGPNGAFNDVAIIWPEKGKPYLLVIYYSE -STLTKQKKAELLAKISESVS--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2G7BXD4_9ACTN ---------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLTTK -PARDAAADSPLVAATATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI000944746E -hrDTRAGLRELEARHGARIGAFAYNLRTKATV-CHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGAYGTSNDVGIAWTPDGAPVALAVLSTK -PAQNAAPDSPLVAAAASVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C06 TaxID=1945854 RepID=A0A1V3P852_9GAMM ---DVEARLAALERRHGGRLGVAILDTGTGRRH-GHRADERFLMCSTHKLLTVGAVLARVD -RGVERLDRRVVFGRDVVLSWAPVTSKHVGAPMSVAELCEAAITVSDNTADNLLLRSLGGP -PAVTAFARKLGDPLTRLDRYEPELNVGAPGDLRDTTTPDAMLGNLRALLLGDVLSVASHE -RLAAWMRATSTGLDKLRAGMPSGWQAGDKTGSGAHDETNDVAIFWPPQRKPLLVTAYLAG -STAGAAGRSAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces katsurahamanus TaxID=2577098 RepID=UPI001295D810 ------SQLAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAVAAVLHRNP ---LSRLSERVTFTQADVNSISPITRDHIGTGMTIRQLCDAAIRHSDGTAGNLLMRDIGGP -ARLTAYLRGLGDTVSRMDHYEPELNRVPPRDPRDTTTPRAIGGDYRRLVLDDALSADKRA -LLKDWLERNTTGDKRIRAGVPRAWTVADKTGTSRYGRANDIAVVWPPGQAPLVVAIMSDR -PGQDTPPKETLIAEATARIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. B27 TaxID=2485015 RepID=UPI000FD6CF13 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLAGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATVRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDPRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKGAESDDALIAGASKVALEAf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WRZ8_9BACT ------RKLAELERHAGGRLGVAAVDTATGQRL-EHRGNERFAMCSTFKFLLAAALLQRVD -KGVEHLNRRIEYGEADLLEYAPVSKQNVKQGMALAEMCSAAVEWSDNTAANLLLQALGGP -DRLTAFIRTLGDEVTRLDNNEPKLNVVLPGEVHDTTSPLSMVRLLSTLLFGQVLSPDSRT -RLQGWMLDAKVGQHRLPAGLPPFWRIAHKTGTGSD-QTNDVGVLWPPDRAPIVVAALYAR -GDIPQDRREAVLADVGRIVSSVf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromonas sp. TaxID=647 RepID=A0A5B9T783_9GAMM ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIATLGPDGKPSRIGVIYMTG -SQA-------------------- ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A429A4W2_9ACTN ------RSLAGLEREHGARLGVYAVDTGTGATV-VHRADERFAICSVFKTLAAAAVMDRGP ---LSRLDERVRYTRDDLVTYSPVTEKHTGTGMTLRELCDAAVRESDNTAANLLLRDLDGP -AALNAYLRGLGDSVSRLDQYEPHLGGNPPKDPRDTTTARAVAADYRALVVGDALPAAKRT -LLTEWLVGSTTGGERIRAGAPRGWKVGDKTGTGDYGRANDVAVLWPERGAPLVLAVLTDR -PDRDAEPSNPLVAEATRRVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000C9AD226 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMNRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=S5TLV0_9BACT ---TYQAKFTQLESNANGRLGIMAINTANNQQI-EYRSNELFPFCSTGKVMVVGAILKASE -SNTQLMQRQLHYSKQDTESYAPITKQHIADGMNVSALSQAAIAYSDNGAMNQLLQLLGGP -QAITSYARSLGDNKFNLVRTEPQLNTAIPNDERDTTTPAAMALSLQKLGLGTALDKKQQT -RLQEWLKANTTGDKRIRAGVPKGWTVGDKTGTGSYGTTNDIAVIWPPHAKPIVLVVYFTQ -NKKDAKPNDQVIAQATKIVIDEf ->[subseq from] Beta-lactamase n=1 Tax=Enterobacterales bacterium CwR94 TaxID=2025587 RepID=A0A2I0G0H9_9GAMM ----TVDKVKTLENKISGRIGYAEIDLASGKLIdGYRTDERFPMMSTFKTLVCGAVLERVD -QGKEHLSRRINYQQSDLITYSPVTEKNIESGMTIEELCRATVSVSDNTAANLLLNIIQGP -QALTHFLRGINDPVTRLDRYEPDLNDAVPGDERDTTSPLAMANTLRKLLKGDTLTAESRD -LLTQWMIGDEVAGALIRSVLPSGWFIADKTGAGRHGSRGIIAMLGPDNQPSRIVVIYITN -SKTDIDEQNRIIAEIGASIIANw ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TP90_9BACT ---DAAARVAAIEARIGGRIGVAALDTSNGKRL-DHRAEERFPMCSTFKFLAAAAVLKRVD -EKQEKLDRFVSYGAKDILEHAPVTKERLKDAMTLGALCEAAIEQSDNTAANLLLDAIGGP -ASLTHFARNLGDQITRLDRKEPDLNSAIAGDERDTTTPGAMCLDMQRLLVASVLSESSRR -QLEDSLLRNKMGGLMIRAGVPKTWSVGDKSGRCANGATNDIAIIRPPDRAPILLAIYSVG -STAPANNREMAIAEVAKIVAELf ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. J56 TaxID=935850 RepID=A0A1X7IWZ2_9RHOB ----VTAAVRQAETELKARVGYAQLDLRSGNVT-GYREDERFPMLSTFKVLVCGAVLARVD -AGKEDLARHINYPATQLVDYSPVTEKHVDDGMTLSALCEAAITMSDNTAGNLLLEAVGGP -EGLTSFLKATGDNIGRLDRWETELNSAIPDDPRDTTTPNAMAKTLHRLLFGDVLSDQSRD -QLLNWMQNDRVADALLRAALPQGWYIADKSGAGDRGARAIVAALGPNGAPERIMVIYMTE -TDAALDERNAQIAKIGKALIANw ->[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter polyhydroxybutyrativorans TaxID=1546149 RepID=UPI0011E4D06C --qQLRAALGRVEQRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD -QGLERLDARVRYGREDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP -AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA -RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ -CPAAPAQRDAAIAEVGSLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. CMAA 1363 TaxID=1843182 RepID=UPI000AC1E58A ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQKYVLGQALPEDKRT -LLTDLMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAKYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase L2 n=1 Tax=Candidatus Sulfopaludibacter sp. SbA3 TaxID=2043164 RepID=A0A2N9MV63_9BACT ----LPAALAQLEQTNGGRLGVAVVDTATGERS-GHRANERFPMCSTFKFLLASAVLQRVD -RHLETLDRAITIPPKPLLGNSPLTEPHAGGTMTVAALCHAALTRSDNTAANLLLESIGGP -ASITAFARSIGDTVTRLDRMETSLNESLAGDPRDTTSPRAIAGDLHRVLLGNVLKPASRD -QLTVWMEANLTGLERLRAKLPKSWHAADKTGSNGEHTSNDIAVVWPAGKPPIIIAAYITQ -CMGPESKRSALLAEIGRLV---- ->[subseq from] Class A carbapenemase SME-5 n=1 Tax=Serratia marcescens TaxID=615 RepID=X4Z2B6_SERMA ---AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYHSPITPKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA -IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR -KSKDDKHSDKTIAEASRIAIQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces parvus TaxID=66428 RepID=A0A5M8GR77_9ACTN -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVTYAREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGRALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSHR -GTKDAEPDDRLIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces malaysiensis TaxID=92644 RepID=A0A291SIX6_STRMQ ---AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR -GDKDADYDEKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces malaysiensis TaxID=92644 RepID=UPI00142EACAE ---AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR -GDKDADYDEKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. CH30_1T TaxID=2604836 RepID=A0A5A9E198_9BACI -------GFKELEKEYDARLGVYALDTGSNQSV-SYRADERFIYASTHKALAVGALLKKKS ---IDDLDKKINFTEKDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAGNLIFEAIGGP -KGLMEVLRGIGDDVTEPDRIEPDLNNVEPGETRDTSTPKALAESLQAFTLGNALPEEKQN -LLNDWLKRNTTGDALIRAGVPEGWIVGDKTGAGSYGTRNDIAVIWPPDGYPIILAVLSSR -EKADAEYDDELIAKATEIAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC05374 TaxID=2487420 RepID=A0A3R9W946_9ACTN -------RLRALERRHGARLGAVARNTVTGATV-LYRADERFPMCSTFKTLAAAAVLRDLD -RHGEVLARRIRYTAADIVVNSPRCEENLATGMTVAELCDATIRFSDNTAANLLLRELGGP -TAVTRFCRSLGDGTTRLDRWEPELNTCEPWRVEDTTTPAAIAGTYERLVLGDALERGDRE -RLTGWLLGNTTSTHRFRAGLPEDWRLADKTGGGSYGTNNDVGVAWTPEGAPVVLAVLTTK -PVQDAPSDDLLVARAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110465 TaxID=1897621 RepID=UPI0009325674 -------DFEELERTFDARLGVYAVDTGTGREV-THNDRARFAYNSTFKALQAAVVLQTYS ---LDGLDKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNAAANLLFDHVGGP -EGLDASLEKLGDDVTRMDREEPELSRWVPGEQRDTSTPRALAGDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPEGWGVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPEDRLIAEAASVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E28A98 -------DFRELERTYGARLGVYAVDTGNGREV-AYNDNERFAYASTFKAFAAAAVLREYS ---LSGMDEVITYSGDDLSAHSPVTEKHVDTGMTLRELCDAAVRHSDNTAANLLLDALGGP -KGLASALAEVGDTATRVERREPELNQWAPGETRDTTTPRAWAGDLRAFVLKDALGRKERA -QLTKWLRTNTTGDELIRAGVPQGWVVGDKTGGGGYGVRNDIAVVWPPDAAPIVMAIMSNR -GTEDAEYDNKLIEEAASVVTR-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00111D4B09 --qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC07061 TaxID=2487410 RepID=A0A429RCH6_9ACTN ---RVARALAALEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD -HDGSVLARRVHYTQADIDRYSEWTKRHLANGLTIAELCEVSITYSDNTAANLLLRELGGP -DAVTRFARSVGDPVTRLDRWEPELNSAEPDRVTDVTTPRAIARTYARLVLGDALGRADRG -LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIVWRPHGAPLVLAVLTTK -PAQDAKADDALVSGAARVLAKAf ->[subseq from] Beta-lactamase n=1 Tax=Porticoccaceae bacterium TaxID=2026782 RepID=A0A2E0LIT0_9GAMM ---DIETRLAEIEASVKGHLGVGILDTKTGAFY-GRRVNERFPLCSTFKFLAAAMILERVD -RGVEQLDRRITFTKSDLAPYSAVTKNRTGAKMTLGELCAAAIAFSDNTASNLMLSSLGGP -KALTQFLRSLGDKATRVDRLLPAASKVSPGDPRDGTTPRAMAYTTQRLLFGNVLSKASET -QLIDWLVSSQTGDARLRAGLPKDWRVGDKTGTCS-GATNDVAVIWPPDRPPIIIAAYLND -TNATAAKRDAALADVARVAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD200 TaxID=1053244 RepID=J8MWY2_BACCE --eQTHQKFSQLEKEFDAKLGIYALDTSTNQTV-IYNPNERFAYASTHKALAVGVLLQKKS ---IEDLDQRIMYTDKDLVNYNPITEKHIDRGMTLKELADASLRYSDNTAQNLIFKQIGGP -DGFKKALQEIGDTVTNPQRIEPELNDVNPGETPDTSTPKALAASLQTFILGDVLPTEKRN -LLIDWMKRNTTGDKLIRAGVPKGWEVADKTGAASYGTRNDIAVIWPPNKKPIVLAILSNR -DKKEAKYNDQLIAEATKIALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS335 TaxID=1169160 RepID=UPI0003804EA8 ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLGELGGP -AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALDKRDRA -RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE118E -----EAQLAALESKHPGRICVSILDLASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLVDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDILTAASRS -QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Acrocarpospora macrocephala TaxID=150177 RepID=UPI0012D3471A ------TRFAALEHKHDARLGVYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP ---LSHLNKRVTYTSAEVNSISPITENHIGTGMTIRQLCDAAVRYSDGTASNLLVRDIGGP -AQLTAYLRGLGDTVSRMDNYEPELNSNPPRNPRDTTTPRAIAADYHKLVLDDALTTGKRA -LLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPDTAPLVMAIMSDR -SGYSTPHKESLIAEAAARIV--- ->[subseq from] Beta-lactamase class A n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2A3II57_9ACTN -----HQTLRRLEREHQARVGAFAHNLTTGARV-AYRAHTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRIHYTRADLVDNSPVTGAHLATGMTIAGLCAAALQRSDNTAANLLLRELGGP -AAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIAHTYTRLLVGDALTPADRG -RLTAWMKANETNTDRFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPVVLAVLTGK -PEQAAACDDALIADVTKVLA--- ->[subseq from] Beta-lactamase n=2 Tax=Micromonospora inyonensis TaxID=47866 RepID=A0A1C6R7L2_9ACTN ---------GALEARFGARLGVYAVDAGSGATV-VHRTDERFAYASTFKALAAAALLDATA ---AQELDRVVRYTRADLLPHAPVTGRHVGTGMSLRDLAEAAVRHSDNTAANLILAELGGP -AGFAGHLRALGDRTTKPTRTEPALNEATPGDDRDTSTPRALATDLRAYVLGDALDAEDRA -LLTDWLRRNTTGGGLIRAGVPAGWLVGDKTGTGGYGTRNDIAVLWPPGRAPIVLAVLSSR -DAEDADHDDALIAEATRVTLD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 70 TaxID=1827606 RepID=A0A2G7EX01_9ACTN --aATGDRLRELEQQHGARLGVFAHNVRTKETV-DHRADELFPVCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP -TAITRFARSIGDPVTRLDRWETELNSAEPWRVTDTTTPRAIGRSYARLVLGDALNRPDRE -LLTHWLLNNTTSGNRLRAGLPKTWTVADKTGAGSYGANNNAGIAWTPEGTPVVLAVQVTK -PERDAAWDHELIAEAAAVLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Alkanindiges illinoisensis TaxID=197183 RepID=UPI00047D5439 ---QVNVFLAQLEKQAQGRLGLSAINTANQMRI-DYRASERFPLCSTFKLVAVAAILQQSM -HNASLLQQHIDFTLQQVQDYAPITAQHVDRGMTVSELCAACISYSDNAAANLLLQILGGP -AALTRFTRHIGDHIFRLDRWEPALNTALPHDERDTSTPTAMTNTLQRLLLGNVLAPTQRE -LLLYWLKNNTTGNARIRAGVPNGWIVGDKTGTGAYGTSNDIGIVWPTQQAPIILAIYFTC -PDKTAKPNDAIIASASRIVCQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 2975 TaxID=2676871 RepID=UPI001359AC6E ------RAFARLEREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEQNS ---LAGLDKVVRYTRDDLVDHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP -KAFQATLAALGDTITHADRLETDLNEATPGDIRDTSTPRALAGDLREYVLGDTLDADRKA -LLIDWLKRNTTGDALVRAGVPGTWEVGDRSGGGDYGTRNDIAVAWPPGGAPVVLAVLSSR -AAQDAEYDDRLVARAAEVVVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q9LAR5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEFCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAGTLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2112.5 TaxID=1907386 RepID=A0A419VI42_9ACTN -----HQTLRRLEREHQARVGAFAHNLTTGARV-AYRAHTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRIHYTRADLVDNSPVTGAHLATGMTIAGLCAAALQRSDNTAANLLLRELGGP -AAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIAHTYTRLLVGDALTPADRG -RLTAWMKANETNTDRFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPVVLAVLTGK -PEQAAACDDALIADVTKVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis ganjiahuensis TaxID=239984 RepID=UPI000349A920 ----LDSEFTRLEEEFDARLGVYALDTGTERSV-EFQADERFAYCSTFKALAFGAVLDRTS ---LEDLDRVVTYSEDDLVFHSPVTQEHVSTGMTLREIGDAALRHSDNTASNLLFEELGGP -EGLGEALRGIGDDVTSVDRTAPEMAEAVPGDERDTSTPRAMAASLRAFALEDVLPEEKRD -VLVDMMRDNTTGDGLIRAGVPDGWEVGDKTGACGYGTRHDVGVVWPPGEEPIVLAVMSSR -DEEGAGYDDALIAQATATAVD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IXX2_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -S---------------------- ->[subseq from] Beta-lactamase n=1 Tax=Blastococcus sp. DSM 44268 TaxID=1550231 RepID=A0A1G7LDL5_9ACTN ----VAPALQQLEAEFGARLGVFALDTGTGRTV-EHRADERFAYASTHKALSAALVLDRTT ---DAELDQVVAYDADDLVAHSPVTERHAGTGLPLREVLQAAVSESDNTAANLLLARLGGP -EGFQQALRDLGDDVTQADRFETQLNEATPGDERDTSTPRALATDLRAFLLGDALSEEDRA -LLTGWMQESTTGSALIRAGVPAGWAVADKSGAGGYGTRNDIAVLERPDGPPIVLAALSSR -DAADAAYDDALVARAAEVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas nasturtii TaxID=1843581 RepID=UPI0007E4ABC9 ----LRARWAEIERGTGGRLGIGLLDSATGWHI-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIHTADMLAHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -AGLTAFLRGIGDAHTRSDRYEPEMNRFAAGDQRDTTTPAAMAATLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGPTREWKIGDKTGSNGTDTRNDIAILWPPEGAPLLLTTYLNG -AKVDAAAREAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia mikamii TaxID=508464 RepID=UPI0007C650CF ------AEFRDLEARLHGRLGVYALDTGTGRTV-EYRPDERFPYCSTFKALAAGALLSSLP ---PAELDRRVTYTRADLVPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAVGDTSTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD -VLTGLLRANTTGAALIRAGAPAGWQVGDKTGAGAYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia stercoris TaxID=2483361 RepID=A0A3M2LE54_9NOCA ---AVDAEFAAMEQEHGARVGLFAVDIRTGKTV-GYRADERFGMASTFKALAAAAVLRAHP -ISTGYLDQTVHFTSDDVVQDSPVTSKHLDSGMSIRELCDAAITYSDNTAGNLLLKQIGGP -QGLTAFARSIGDEVTHLDRWEPELDAMDPGDDRDTTTPAALTADYRALIFGDVLATPERD -QLTAWLVANKTGNARIRAALPPDWKTGDKTGTALYGSANDVAVTWPADGGPLVVAVLTTK -PDQAAAADNPLVAAVAKVAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas translucens pv. poae TaxID=227946 RepID=A0A199P9P5_XANCT ---TLAQRLAGIERRAGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELSLRQPVQIRAADMLSHAPVTERHVGGALSVAELCRATLIYSDNPAANLLFPLVGDP -PGLTRFLRGLGDTQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRALLLGDALQPASRE -QLAAWMLDNRTGDDCLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDDAARDAALKAVAVAM---- ->[subseq from] Class A beta-lactamase n=1 Tax=Paracoccus kondratievae TaxID=135740 RepID=A0A5P8JLU4_9RHOB ----VTAAVRQAETELKARVGYAQLDLRSGNVT-GYREDERFPMLSTFKVLVCGAVLARVD -AGKEDLARHINYSATQLVDYSPVTEKHVDDGMTLSALCEAAITMSDNTAGNLLLEAVGGP -EGLTSFLKATGDNIGRLDRWETELNSAIPDDRRDTTTPNAMAKTLHRLLFGDVLSDQSRD -QLLNWMQNDRVADALLRAALPQGWYIADKSGAGDRGARAIVAALGPNGAPERIMVIYMTE -TDAALDERNAQIAKIGKALIANw ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. B2-1-3A TaxID=2589971 RepID=A0A504BR34_9RHIZ -------KIRRIEAKSGGRLGVACRIAGTAVQF-GYRENELFPMCSTFKTLAAAFILHRVD -GGIEQLDRSIEVPHNAVVANSPTTKNHAGGVMTVAQLCEAAVTVSDNGAANLLLASFGGP -PQLTAYLRSIGDTVTRLDRIEPELNESVPGDPRDTTSPLAMIEDYERLTLGDSLSQKSRA -QLVDWLVANKTGDDRIRAGLPKGWKCGDKTGTGEHGSTNDAAVIWPMSGNPVLMSVYLTG -TKQSLAKRNATIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA60BE5 ------ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGLEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAKSLREYALGDHLSADKRQ -LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH -DEADANANDDLIAEAAEAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD196 TaxID=1053243 RepID=R8GNX0_BACCE --eQTHQKFSQLEKEFDAKLGIYALDTSTNQTV-IYNPNERFAYASTHKALAVGVLLQKKS ---IEDLDQRIMYTDKDLVNYNPITEKHIDRGMTLKELADASLRYSDNTAQNLIFKQIGGP -DGFKKALQEIGDTVTNPQRIEPELNDVNPGETPDTSTPKALAASLQTFILGDVLPTEKRN -LLIDWMKRNTTGDKLIRAGVPKGWEVADKTGAASYGTRNDIAVIWPPNKKPIVLAILSNR -DKKEAKYNDQLIAEATKIALD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas vasicola pv. vasculorum NCPPB 206 TaxID=1094181 RepID=A0A5K1MYY9_XANVA ----LRAQWAEIERGTGGRLGISLLDSATGWHL-GQRQDERFPMCSTFKFVLAAAVLQRVD -QGKLMLAQRVKIRASDMLEYDPVTERHIGGSLSVGELCRATMIYSDNPAANLLFPLVGDP -AGVTAFLRSIGDAQTCSDRHEPDMNRFAAGDPRDTTTPAAMANTLRTLLLGDALRPASRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGIDTRNDIAILWPPKGAPLLLTAYLNG -AKVADAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium sp. ERR 942 TaxID=2572676 RepID=A0A560M106_9RHIZ -----EAQLAALESKHPGRICVSILDLASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLVDYSPATEPNTGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDILTAASRS -QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. Soil745 TaxID=1736396 RepID=UPI0009EC948A ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQES ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKELEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000767D9B9 ---AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP -KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA -RLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0007DB2B66 ---AFTGAFKKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP -KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERA -RLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF84C1F -----KHSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASNHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVDTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPKLNEVQPGDTRDTSTPMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPEEWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAVLSNH -AKEDAKYEDKLIADATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=A0A286CBL9_9ACTN -----TARLRDLEREHTARLGVYGRNLRTGRTV-VYRAGERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAVTRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGTALEPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. NRRL WC-3656 TaxID=1463824 RepID=UPI0004C42603 ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYALDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGNYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. M56 TaxID=1495638 RepID=A0A2K8RG90_9ACTN ---AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR -GDKDADYDEKLIAEAASVVAD-- ->[subseq from] Class A beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A6B1M571_9ACTN ---AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR -GDKDADYDEKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia rhamnosiphila TaxID=426716 RepID=UPI0004C44F5A -----TQQFADLEAAHGARLGVFALDTADGRSV-AYRDGERFPMASTFKGLACGALLHKHP -LSSGFFDRVIQYPRTDLVENSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLDGP -AGFTAFLRALGDTTSRLDRWETELNTAIPGDERDTTTPAALVADYRALVVGDSLAEPERA -QLSAWLVASATGGNRIRAGLPAGWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK -SEQDAEPDNALVAAAARAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK447 TaxID=2512159 RepID=A0A4R7IY66_9ACTN ------NELEELERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS ---LSGMDKVVRYSEDDLVANSPITEEHVETGMTLSELCDAAVRYSDNTAANLLYEELGGP -KALEAELRKLGDQVTSMDRIEPDLSNWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA -QLTTWLKTNTTGNEVIRAGVPEGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR -GKADDTHDNKLIAEAASVVADK- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. KC06 TaxID=2530369 RepID=A0A4R4XUP3_9ACTN ---DVTAKLRGLEKARDVRIGAYAVDTGTGRFV-GHRADETFPFASTFKAIVCGAVLRKAD -SDPGLLDRVIRYKKSDLAPFSPVTEKHVGTGMTVADLCHATITRSDNAAGNLLLKQIGGP -SGLTAFLRSLGDTVSRSDRWEPGLNDWKPGERRDTTTPRAWAGSLRALTVGDALAPADRD -RLIGWLKAAVTGGARIRAGLPEGWTAGDKTGTAGYGSANDIAIVWPPSRAPLVIAILTTR -PGAGAEADERAVAETARVLTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBF8AAB -----DQEFRRLEEQFGARLGIHAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSARDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD -VLRGWLRGNTTGAALVRAEVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DRKDATPDDAVIAQATRVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces angustmyceticus TaxID=285578 RepID=A0A5J4LLU1_9ACTN ------AALRRLEHAHRARVGAFAHNTVTGATA-AYRAHARVPLCSVFKTLAVAAVLRDLD -RDGETLARRIRYTAADLVDNSPVTERHVATGLTIADLCAAALRRSDNTAANLLLRELGGP -AAVTAFARSLGDRTTRLDRWEPDLNSAEPWRTTDTTSPAAIGTAYARLLVGDALAPSDRG -RLTAWMKGNETSAHRFRAALDEDWTVADKTGTGSYGTGNDVGVAWTPDGTPIVLAVLTSK -PEQAADADDALIASVTRVLVR-- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. M7D.F.Ca.US.005.01.1.1 TaxID=2493678 RepID=A0A3S9DZ19_9RHIZ ----VLPKIRRIEAKSGGRLGVACRIAGTSAQF-GYRENELFPMCSTFKTLAAALILHRVD -SGIEQLERSIKIPHNAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP -PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTTSPLAMVEDYQRLALGTSLSDKSRA -QLVEWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG -TKQSLTKRNAVIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00081B7B06 ---DTADAFEKLEAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPDSPVTEKHVGTGMTLDALCDAAVRYSDNTAANLLLDRLGGP -KGLGALLAELGDGVTRMERLEPELSRWVPGSTRDTTTPRAFAENLRAFVLGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDNWAVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLTNR -DGEGDAYDNRLLAKAAAVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A0L1LT32_BACME ----SDREFAKLEDKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLDERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKGAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A3D8X0J5_BACME ----SDREFAKLEEKYDAKLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLEELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGEIHDTSTARALAASLQTYVLGQALPEEKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSNR -TEKDAQYNDELIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 2231.1 TaxID=1855347 RepID=A0A1H5GYV7_9ACTN ----VEAELRDLEQRYDARLGVYARNVRTGRTL-SHRAGERFAMCSTFKAFAAAAVLRDRG --DRAPLDRVIHYPPHDILPNSPRTQENLATGMTVGDLCAAAIQYSDNAAGNLLLREIGGP -AGLTRFLRSLGDDVSRLDRWEPELNTAIPGDLRDTTTPRAIGGSLARLGLGRALGDADRE -RFVGWLKGNTTSTGRFRRGLPDGWVLADKTGTGSYATANDIGVAWTARRTPVVLAVLSTR -STEDATVDEALVAEAARVIAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=UPI000489FA96 ---QLTAAAQQEEKTLNARIGVAVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD -EKKVSLTEAVRFDKSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKVGGP -QGVNAFLRANGDKTTRLDRVEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK -QLTRWMIDDKVADALLRQSLPKGWTIADKTGAGGYGSRSIISMVWPEKGTPLVVAIYITQ -TDASLSQSNAAIARLGHVIFQQ- ->[subseq from] Beta-lactamase n=1 Tax=Marinospirillum alkaliphilum DSM 21637 TaxID=1122209 RepID=A0A1K1XG11_9GAMM ---ALVTELQRIESDLKARIGFSAHDLETGLRW-EHHADQRFAMSSTFKTLACAALLQQVD -ENEVQIERKISFSEADLVTYSPVTEQHAGQRMSLFELCEATMTTSDNTAANLILQAIGGP -EAVTEFVRGIGDDVTRLDRWETELNQATPDDERDTTTPNAMVANLEALLLGNVLSPSSRG -QLREWLVGNKVADGLFRSSMPADWVIADRTGAGGFGSRSITAVIWPPERLPVVVAFYITE -TTASFDDRNAAIAALGRVIK--- ->[subseq from] Beta-lactamase n=1 Tax=Terribacillus halophilus TaxID=361279 RepID=A0A1G6JAM9_9BACI ----TQEPFADLEKTYDAHLGVYAVDTGSGKTV-AYRENERFGFASTHKALSAAVLLQQNS ---LEDLNKKIMYTSDDLVNYNPITEKHVKSGMTLKELAEASVSYSDNTAANLIFEEIGGP -AGLKQALRDIGDQVTEPARIEPELNNVKPGETQDTSTPKALAESLRAFTLEDSLSPENRQ -LLIDWLKGNTTGDNLIKAGVPKEWEVGDKTGAGSYGTRNDIAILWPPDSEPIVMAIMSSR -DEADASYDDALIAEAAQEVV--- ->[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1P2K5_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRA---------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces californicus TaxID=67351 RepID=UPI0004AA4345 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLDKYS ---LDGLDQRVTYTRKELVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces argenteolus TaxID=67274 RepID=A0A561QBY3_9ACTN ---RTARAFRELERTFDARLGVYALDTGSGRTV-THRADERFAYASTCKALLAGAVLSRNS ---LRQIDRLVRYDRDDLISNSPITERHIATGLTLRELCDAAVRYSDNTAANLLFRELGGP -QGLQDALRAEGDNVTRCDRYEIALSDAVPGDVRDTSTPRALAHDLRTYVLGTTLPADKRT -VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGSGGYGTRNDIAIIWPPDAAPITLAVLSRR -DTKDAERDDALIARAAEVALR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. XY152 TaxID=1415560 RepID=UPI0006ADEBC7 -----APEFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKHG ---TGGIDKVVTYARGDLVAYSPVTENFVGTGMSLRDLCAAALWYSDNTAVNLLLDELGGP -DGLEKVLEEFGDDVTEMDRYEPELNDAAPGDIRDTSTPRAMAESLRAFLLGDALKRDERE -LLRQWMTTNTTGRTLIRAGVPDGWDVADKSGSAGYGGRNDIAVVWPEDGDPVVMAVMSTR -GKEGADRRDALVAKAATVAAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00140FD3CB ------PDFTALEAASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFVLCAAVLRQVD -AGRLDLDKRVPMRAEDLIDHAPVTRRHIGKDLTVRDLCRATMITSDNPAANLLLGVVGGP -PAVTRFLREHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFLLGQVLAPASRQ -QLADWLIDNETGDERLRAGLGSTWRVGDKTGSNGKDTTNDIAMLWPMGGTPWVLTSYLQG -ATVDDAGRNDVLRQVAV------ ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus vietnamensis TaxID=351656 RepID=A0A1Y2SAX8_9GAMM ---EIIDQLSMLEKNANGRLGVVLIDTSDHSTI-TYRANERFPLCSTSKLMVASAILKKSE -INTHLLNQRIHYQQSDLVEYSPITEKHLKDGMTLGELSAATLQYSDNTAMNLLLNQLNGP -SEVTKFARAIGDNHFRLDRQEPELNTAIPGDERDTSTPQAMAKSLYNLALGNALATTQRE -QLIEWLKGNTTGNTSILAGVPKGWVVGDKTGRCDYGTTNDVAVIWPPKRAPLVLVTYFTQ -PDQEGRARPDVLAAAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 6-11-2 TaxID=2585753 RepID=UPI001143DFA3 ----TTARLRALEQGHGARLGVFAHNPATGRTV-RYRADERFPMCSVFKTLAAAAVLRDLD -RHGKVLSRRVHYTEADLVLGSDQTRAHLATGMTIAELADVAIRFSDNTAGNLLLRELGGP -TAVTRFARSLGDPVTRLDRWEPDLNTAEPWRLTDTTSPRAIGRTYARLVLGDALNRDDRR -LLTRWLLNNTTSANRFRAGLPPTWTVADKTGSGAHGTTNDVGVAWTRSGSPVVLAVLSTK -PARDAPYDDALVARTAAAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01373 TaxID=2020325 RepID=A0A2M9IRS3_9ACTN ----TTARLRALEQEHGARLGVFAHNPGTGRTV-RYRAEERFPMCSVFKTLAAAAVLRDLD -RHGEVLSRRVHYTEADLVPGSDQTRAHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAITRFARTLGDPVTRLDRWEPDLNTAEPWRLTDTTSPRAIGRTYARLVLGDALNRRDRR -TLRHWLLNNTTSTHRFRAGLPPTWTVADKTGTGAHGTANDVGVAWTESSSPVVLAVLSTK -PAQDAPYDDALVARAAAVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Corynebacteriales TaxID=85007 RepID=UPI0007EA87E1 ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNATIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=A0A2S6AG86_9NOCA ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNATIARAATIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=UPI000CEA1ECB ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNATIARAATIAI--- ->[subseq from] Beta-lactamase n=2 Tax=Nocardia sp. 852002-20019_SCH5090214 TaxID=1834087 RepID=A0A1A0KK32_9NOCA ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNATIARAATIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillaceae bacterium MTCC 10057 TaxID=590062 RepID=UPI0005896971 ---NTNERFIQLEKEFDAQIGVYAIDTGTDQTI-EYRPEERFAFASTYKALAAAILLKQNS ---LEELEKVITYTEDELVPYSPVTEKHVDTGMTLLELGEAAVRFSDNTAGNLLFEAVGGP -QGFEQALRQIGDDVTEADRLEPDLNKFTPGDTRDTSTPRALATSLQAFAVGGLLSGDERE -LFTDWLKGNATGDPLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNRKPIVMAVLSRH -HTEDAAYDDELIAQAAKITLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus atrophaeus (strain 1942) TaxID=720555 RepID=A0A0H3E3D2_BACA1 -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETDLNSAIPGGIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus sp. lzh-N1 TaxID=2069255 RepID=UPI000C80E6DA ------VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDNVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTKDAEYNNALIAEAAKAAFK-- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. M-152 TaxID=2487928 RepID=A0A3G8RGI2_9BACL ------VVFKQLEVKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDGLGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKLLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTKDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. CCH9-E1 TaxID=1768768 RepID=UPI00082E4FF2 --kALSSRINELERASGGRIGVAVLDTQDGRRF-AWRGDERFRMCSTVKAPLSAAILRRVD -QGRERLDRRVTFGPEVLMGNSPIVEKHVQDGLTIGQLCEATITLSDNAAANLLFEALGGP -AALTRFLRAIGDQTTRSDRLEPALNGGAPDDPRDTTTPSAIVATWKALLLDDALSPASRQ -RLRDWLIANKTGDRRLRAGLPPGWRVGDKTGNNGKDITNDVAIAWPPGRGPVLIGVFHDR -GG-DEDARNTVHANVARAVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces albulus TaxID=68570 RepID=A0A401QVG6_STRA9 ---SFEGELQELERRYAARLGVYARNARTGQVV-AHRARERFAMCSTFKTVAAAAILRDHA --RCAPLDKVIHYPPADLLANSPRTAEHVDTGMAVGDLCAAAIQYSDNTAANLLLRQIGGP -AGLTRFFRSIGDRESRLDRWETELNDAVPGDLRDTTTPEALGTSYGRLTVGRALDPAARE -HLVTWLKGNTTSGERFRAGLPHDWVVGDKTGTGDYASANDVGVAWTTRQTPIVLAVLTSK -DAKDAPVDNALIADAARIVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI000B43D9FA -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETDLNSAIPGGIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVALN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella sp. TaxID=576 RepID=A0A2D2CI77_KLESP ------EQIKLSESQLSGRVGMIEMDLASGCTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERN-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bacillaris TaxID=68179 RepID=UPI000DD6F932 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAESDDALIAGAAKVALEAf ->[subseq from] Beta-lactamase n=1 Tax=SAR86 cluster bacterium TaxID=2030880 RepID=A0A2A5B844_9GAMM ------ATAIEIEKRLGARLGLAVIDEETGKRW-NYQADQRFPMCSTFKAIAVGAVLAQVD -KGEDSLNRVVNIAEGDLVSYSPVTENRLGGTMTLAEICEAALTMSDNTAGNKLLESIGGP -DGLTAFARLIDDNVSRLDRWETGLNEAAIGDVRDTTSPEAMSQTLRSLLLGDVLSSNSRE -QFKEWMVNNKTGDAKLRAGVPSSWQVGDKTGGGNNGTMADIAIIWPPNRKPLSIAVYMTE -TDASFDDRNLGISEIAAAL---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces caelestis TaxID=36816 RepID=A0A0M8QFM4_9ACTN -----APEFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKHG ---TGGIDKVVTYARGDLVAYSPVTENFVGTGMSLRDLCAAALWYSDNTAVNLLLDELGGP -DGLEKVLEEFGDDVTEMDRYEPELNDAAPGDIRDTSTPRAMAESLRAFLLGDALKRDERE -LLRQWMTTNTTGRTLIRAGVPDGWDVADKSGSAGYGGRNDIAVVWPEDGNPVVMAVMSTR -GKEGADRRDALVAKAATVAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax ebreus (strain TPSY) TaxID=535289 RepID=B9MI58_ACIET --qQLQAALGRVEQRVGGRLGVAVLDTGSDALA-TYRGDERFALCSTFKLLLAGQVLQRAD -QGLERLDARVRYGRHDLVEYSPRTEPHAGGAMTVAELCEATMVLSDNSAANLLLRRQGGP -AGLTAWLRTLGDAHTRLDRIEPALNDVPAGELRDTTTPRAMVHTVQKLVLGDALSGEARA -RLQGWLLGNLTGDKRLRAGMPAGWRIGEKTGTAN-GTSNDVGVVWPEGGAPAVVACYLTQ -CPAAPAQRDAAIAEVGSLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis chromatogenes TaxID=280239 RepID=UPI00034AC9C8 ---QADADFADLEEEFGARLGVYAIDTGSGEEV-AYNADQRFAYASTFKVPACGAVMEEYS --LKEMRKHVVHFDEEDLVDYSPITEDHVDSGMTLMEVCDAALRYSDNTAANLLLEELGGP -EGFQEAMRELGDDTTISARWETELNENKPGDERDTTSPRAFAQNLEEYVLGDVLEKKERK -ALADMMVRSTTGDTLIRAGVPKNWKVGDKSGMPGYGGRNDIAVMWPPKGDPIVLAVYSTK -DTEDAESEDALVAQAAEVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea anthophila TaxID=470931 RepID=A0A506P6C4_9GAMM --qSLNNQFEKLERQSGGRLGLAVIDTSDSTQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIHISQRDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A0J7EFX0_9BACI ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMNLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=UPI000CE9E288 ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGSYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDADYDNATIARAATIAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3549 TaxID=1463925 RepID=UPI0004C91FB8 -------AFGGLEEKYGARLGVYALDTGTGREV-THNADERFAYASTFKALAAGAVLRTYE ---VSGMDWLVTYSEDDLVPDSPVTEKHLATGMTLDALCDAAVRHSDNTAANLLLERLGGP -KGLNVLLRQLGDDVTRMERLEPELSRWEPDSTRDTTTPRAFAGNLRAFVLGDVLGDAERN -RLTHWLRTNTTGDELIRAGVPEDWTVGDKTGAGGYGVRNDIAVLWPPDRAPVVVAIMSNR -GRADAPYDNRLIAEAAAVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Inquilinus limosus TaxID=171674 RepID=UPI000417B29F -----GARLAELERAQGGRLGVAVLDLATGARI-GHRADERFLLCSTFKALAAAFVLARVD -QKKEQLDRRVVFSRKDIVAGPSVIEHRVGGAITMAELCDAAVTYSDNTAGNLLLASFGGP -PALTAFLRSLGDEVSRLDRTEPELNAAGPGDPRDTTTPAAVLETLRKLLFGDALSRRSRD -QLAAWLITNKTGDTRLRAGFPADWLVGDKTGTGGEKSTNDVAIAWPPGRGAVIVTAYCEL -PSASFEQRNAVVAEIGRIVSQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sontii TaxID=2650745 RepID=UPI00129A8F0A ---TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDAQTQLDRNEPGMNAFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B90387 ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQTLPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=1 Tax=Serratia fonticola TaxID=47917 RepID=Q6JP75_SERFO ------DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ -QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP -EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH -QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVGHAPIVLAVYTSK -PDKNSKHSDAVIADASRIVLESf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium zhanjiangense TaxID=1325107 RepID=A0A4Q0SUG0_9BRAD -------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEGLSPTSRA -QLTEWMVNCKTGANRLRGGVPAGWRIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG -GTPSAAQIAAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. ARC270 TaxID=2027923 RepID=UPI000DA780E8 --qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQRA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ -HDKNAAARKDVLASAARVIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000767912D ----FTGAFRKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP -KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERT -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR -GDKDTTFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1EB593 ---ELRYKWAEIQRGSGGRLGISLLNSDTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTLFLRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDGCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD585C --dEIDRRIAALEKQIGGSIGVSVIDTQTNISL-GYRETESFPLCSTFKVLAAGFVLARVD -KGEENLERRIIYDTDKLVTYSPETGKHVGGDMSVGDLCQAAITLSDNTAANLLLESFGGP -KELTNWLRTFGDASTRLDRWETDLNEGKKDDPRDTTTPDAMLDTLGNLTLGSVLSEPSQN -TLVEWMVANTTGGARLRPGLPDDWKIGDKTGTGNNGCAADIAIAWPPGHGPLLMTVYVKQ -ANVPVADINPVFAEVGRIVTD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDA0_ECOLX ------EQIKLSESQLSGSVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVADRVAGPLIRSVLPAGWFIADKPGASKRGARGIVALLGPNNKADRILVIYLRD -TPASMAERNQQI----------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3723 TaxID=1519491 RepID=A0A0M8XA35_9ACTN -----HAELAELERRYGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDQA --DCAPMDRVVHYPPHDILPNSPRTEENLATGMTVADLCAAAIQYSDNAAGNLLLRELGGP -AGLTRFYRSLGDEVSRLDRWEPELNTAIPGDPRDTTTPEAIAASLERVTLGRALARADRE -RFVGWLKGNTTSSARFRKGLPREWVVADKTGTGDYATANDIGVAWTTRRTPLVLVVLSSR -TTPDAPVDEAPIADAAAVVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00112BB390 ----SDREFAELEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQTYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 70 TaxID=1827606 RepID=UPI000C1A9D07 --aATGDRLRELEQQHGARLGVFAHNVRTKETV-DHRADELFPVCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP -TAITRFARSIGDPVTRLDRWETELNSAEPWRVTDTTTPRAIGRSYARLVLGDALNRPDRE -LLTHWLLNNTTSGNRLRAGLPKTWTVADKTGAGSYGANNNAGIAWTPEGTPVVLAVQVTK -PERDAAWDHELIAEAAAVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Leaf78 TaxID=1736237 RepID=A0A0Q4RWE7_9BURK ---AWNDTLAGIERTAQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPASGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDGMTRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPASRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTTNSGTSNDIAVMWPPGGAPVVVTCYITA -STASSEQRDAAIAQVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas aestuarii TaxID=568898 RepID=A0A2U1V0N3_9PROT ---ALEARLRAIEAETGGRLGVAVREAAPGGLRaGHRAAERFPLTSTFKLLAAAAVLRRVD -AGQERLDRVLRFSSADLVTYSPVTRPQADGPMTLEALCAATVTLSDNTAGNLVLGTLGGP -AGLTAFARDLGDPVTRLDRWETALNEATPGDPRDTTSPEAMLGLIGALTLGEALSAASRE -RLMGWLLGNRTGDRRLRAGLPAGWRAAEKTGSGGRNTANDVGLLLPPGGAPILVTVYLTG -ATAPAEARDAAIAAVAEAVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces halstedii TaxID=1944 RepID=UPI0013CC7409 ---ETAEAFEKLEGEFDARLGVYAVDTGTGREV-THRADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPNSPVTGRHVGTGMTLDALCDAAVRHSDNTAANLLLDRLGGP -KGLGALLAELGDDVTRMERREPELSSWVPGSTRDTTTPRAFAGNLRAFVLGDVLGDAERA -RLTRWLRTNTTSDEVIRAGVPDDWTVGDKTGTGGYGIRNDIAVLWPPDRAPVVVAVLSNR -DGEDDAYDNRLLAKAAAVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. AS23.2 TaxID=1680155 RepID=A0A1Q5RBZ5_9BRAD -------EIASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGDEQLASMIPYGQADLLSHAPAAKQNLATGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPHDTTTPAAMAGNLRRLVLGEGLSPASRA -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDAAGDIAVAWPKADTPILIAAYTQG -GTPSAAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A212MHV7_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLKDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTT- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A1A9Q140_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGLTLKELADASVLYSDSTAHNLILKQLGGP -SEFEKILREMGDIVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus thuringiensis serovar coreanensis TaxID=180843 RepID=A0A193CSU8_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASKSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAEYDDKLIADTTKVVLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. LLH-Irr-9 TaxID=1564892 RepID=A0A097SRQ4_9ACTN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVFIYTTG -SRV-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=UPI000BE3CAE0 -----TARLRDLEREHTARLGVYGRNLRTGRTV-VYRAGERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAVTRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGTALEPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI00096EAE32 ----LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHASVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFMRGIGDTKTRSDRLEPEMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0004C4CCDB ---RAAARFRALEERYGARLGVHAYDVRTGRVL-AHRDRERFPMCSVFKTLAVAAVLRDLD -HDGSFLARRVHYTAADVERWSPVTGDNLARGMTVAELCDATLRFSDNTAANLLLRDLGGP -TAVTRFARSAGDPVTRLDRWEPELNSAEPWRTTDTTTPRAIARTYGRLLLGRVLDPADRA -LLTDWMLRNTTSDARFRKGLPADWTVADKTGGGDYGGNNDVGVTWPPDGGPILLAVLTTR -RDRDAEGVDELVAAAAAVAADE- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzicola (strain BLS256) TaxID=383407 RepID=G7TCU9_XANOB ---MLRAQWAEIECGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLTQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag109_G2-15 TaxID=1938850 RepID=A0A286HGJ4_9ACTN -----HAQLSDLEQRYGARLGVYAHNVRTGRTV-AYRAGERFAMCSTFKTFAAAAVLRDHG --GCAPLDRVIHYPPRDILPNSPRTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP -DGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEAIGRSFERLTLGRALDGTDRE -QLVTWLKGNTTSAERFGRGLPQGWVLGDKTGTGDYATANDIGVAWTTRGTPIVLAVLSTK -AAKDAPVDNALVADTARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces libani subsp. libani TaxID=68044 RepID=A0A640TG79_9ACTN ---RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST ---DDELNRVINYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP -AGLQKALRGMGDRTTRTDRTEPTLNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR -GSKDAASDDALIRDATKT----- ->[subseq from] Class A beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525L175_9CAUL ---AAETRIKALEAELGGRLGVAALDTGTGRRI-AWRAHERFPMCSTFKLLAVSAILHRVD -TDCETLERQILVDKADVVGWAPVTEKHIGETLPLAMLCEAGITQSDNGAANLILTALGGP -QGVTGYARSIGDRTTRLDRREMALNEGTPGDPRDTTTPSATLGDMRKILTGKALTEVSRK -RLTDWLVADQMGGARIRAGAPAGWRIGDKTGTGGHNATNDLAILWPPGRAPILVAAYSHG -SPKPTDACQTALAEIGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas deserti TaxID=1817963 RepID=A0A1V2GVP6_9PROT ----LEQRLAEIEARSGGRLGVAILVAGTARHA-GHRLDERFPLCSTFKVLAAAAVLARVD -AGQEQLDRPIRFTRDQLVAYSPGTEAGAGGPLPMRHLCEVAVTLSDNTAANLMLQSLGGP -AGLTAWLRGLGDATTRLDRIEPELNEGTPGDPRDTTTPLAMSQTLEKLILGNALKPDSRA -LLTRWLVENKTGDDRLKARLPSGWRAGEKTGTGPRGSTNDAGILWPADSAPLLVSAYLTG -TSAPLAARNAALAEVGKAVAEFy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI000A3074C8 ---ALTSSFAELETTHSARLGVYAIDSGTGRTV-VHRDGERFPIASTFKGLACGALLRDHP -LATGYFDQVIHYSRSELVANSPVTEKHVDTGMTVAELCDATITLSDNTAGNQLLKLLGGP -EGFTAFLRSIGDTVSRLDRWEPELNTAIPGDERDTTTAAALATDYRNLVLGDILAEPERE -RLKSWLVAAKTGGARIRAALPADWTVGDKTGSPAYGGALDVAIAWPPGRAPLVIAVLSTK -FEQNAEADNPLVAEAARAAI--- ->[subseq from] Beta-lactamase n=2 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A561DJ87_9BACI ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDTLPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. LUP47B TaxID=1890286 RepID=UPI0009A048CD ---DITARLRALEERYDARLGVFAHHLATERSV-RFRAGERFPMCSVFKALAAAAVLRDLD -RDGEVLARRIHYTEDDLVIGSDQTAAHLAEGMTIAELAEVAITYSDNAAGNLLLRELGGP -TAITRFARSLGDGVTRLDRWEPELNTAEPWRHTDTTTPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSVNRFHAGLPKTWAIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM -PAQDAVRDDALIADAARAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 196(2019) TaxID=2683820 RepID=UPI0013EB342B ----TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT ---LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVEDAEPDDALIAGAARVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA4EBE9 ------ASFSSLEETYDARLGVFAIDTGTGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ -LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH -DEADAKADDDLIAEAAETAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E0F8B12 ---MLRAQWAEIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQPVKIRAADMLEHAPVTKRHVGGALSVGDLCRATMIYSDNPAANLLFPLVGGP -PGVTAFLRSIGDAKTRSDRYEPAMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTRGWKIGDKTGSNGTDTRNDIAILWPPQGPPLLLTTYLNG -AKVDDAARDTALKAVAVAVREW- ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. TaxID=34009 RepID=A0A2E2JWK5_9RHOB ----ISAELARIEQALDARIGFAAHDLATGQRW-EVNADERFAMSSTFKTLACGALLEQVD -EGLLAPDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP -EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ -QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYLTE -TDASFEARNEAIASLGEVVQ--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia nova TaxID=37330 RepID=UPI000CEA1376 ------AEFHDLEARLHGRLGVYALDTGTGRVV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLLPNSPVTEQHVDQGLTVREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDPTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPAVAADDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNATIARAATIAI--- ->[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1C6MSW2_9ACTN ----TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT ---LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAARVALEAf ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A3A4RHS1_9BURK ----VQDALRDIEATARGRLGVHIIDTATGREQ-GWRADERFLMLSSFKLLASALVLARTD -RGEESLERRIRYRAQDLVPWSPVTEQHVGGELSLAQLCEATLTTSDNTAANLILASYGGP -AALTAFARRLGDTVTRLDRTEPELNRAASGEPLDTTTPRAMAHTVRTLLLGDALSPASRE -RLLQWLLANTTGGKRLRAGVPAGWRVGEKTGTAGD-DANDVGIAFPPQRAPLIVTAYLAE -SATDGATRDAALASVGRLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00316 TaxID=1703932 RepID=A0A1Q5EVF2_9ACTN ----TDRAFAELERTFDARLGVYAVDTVDGRTI-THRPDERFAYASTCKALLAGAVLAKKT ---LPQMERLVRYGRRDLVSYSPIAEQHVATGMTLRALCDAAVRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDPRDTSTPRALATDLRAYVLGSALPAEKRA -VLTDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 69 TaxID=1827605 RepID=A0A2N0J4Q6_9ACTN ----TRAELTDLEQRYGARLGVFARNLRTGQTV-AYRAGERFAMCSTFKAFAAAAVLRDQA --DCAPLDRVIHYPPRDILPNSPRTEENLATGMSVHDLCAAAIQYSDNAAGNLLLREIGGP -DGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEALGRSFERLTLGRALDPADRE -QLVTWLKGNTTSKKRFGAGLPQDWVLGDKTGTGDYATANDIGVAWTTRRTPLVLAVQSTK -AAKDAPVDDALIADTARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI00094A0865 ---MLRSQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDS -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1H2HN89_9PSEU ---QFHDRLMELEKKYDARLGVYALDTGDGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVRYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLAADKRD -FLRDLLQRTVTGAGRIRAGLPPGWTVAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -AAKDAPYDEALLAEAAKYVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS606 TaxID=1305837 RepID=UPI000D119547 ---RLARRLTELENRHAARLGVFAHDTATGRSV-QYRAQERFPMCSVFKTLAVAAVLRDLD -RHGEFLARRVRYDEKTVTDYAPVTGKHLAHGMTVEELCDAAIRYSDNAAANLLLRALGGP -RAVTRFCRSVGDRVTRLDRWEPELNSAEPGRRTDTTTPRAVAGTYARLTLGDALDRGDRR -RLTGWLLGNTTSGAKFRAGLPDGWAVADKTGGGEYGTNNDVGLTWPPGHPPIVLAVLTTR -FTPDAERIDPLVAEAASLVAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces phyllanthi TaxID=1803180 RepID=A0A5N8WHX8_9ACTN -----AGALKELEREYDARLGVYAIDTGTGREV-AYRAGERFGYHSTFKALQAAAVLRKYS ---LNGMNEVIRYSEDDLIANSPVTEKHVETGMTLRELCDAAVRYSDNTAANLLYDKLGGP -KALEAELRRLGDKVSRMDRIEPELSKWVPGEKRDTTTPRALAKDLRAYVLGDVLGKRERA -QLTKWLKTNMTGDELIRAGVPEGWVVGDKTGSGYYGARNDIAVVWPPDSAPIVMAILTNR -GEEDDTYDNKLLAEAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85) TaxID=291331 RepID=Q5H347_XANOR ---MLRSQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDS -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BFB8BD2 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWTPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI0004E0AF1E ---EMKDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDWMKRNTTGDALIRAGVPDGWEVADKTGAASYGTRNDIAIIWPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_O1-9 TaxID=1938856 RepID=A0A3D9W6T4_9ACTN -----HAQLSDLEQRYGARLGVYAHNVRTGRTV-AYRAGERFAMCSTFKTFAAAAVLRDHG --GCAPLDRVIHYPPRDILPNSPKTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP -DGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEAIGRSFERLTLGRALDGTDRE -QLVTWLKGNTTSAERFGRGLPQGWVLGDKTGTGDYATANDIGVAWTTRGTPIVLAVLSTK -AAKDAPVDNALVADTARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI000BE5B8A1 ----------LQEERLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITQSDNTAANLLAKKLGGP -AAVTRFFADSGDSVTRLDRGEPELNSAVPGDLRDTTTPLAVSHTLQKLALGELLTPRSRA -QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD -TKATMAQSNDAIARIGKAIFS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MD98_ECOLX ------EQIKLSESQLSGRGGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAMLARVD -AGDQQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLVPNNKAERIVVIYLRD -TPASRAERNQQI----------- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. LM7 TaxID=1938607 RepID=A0A1S6FJZ5_9SPHN ---AFREAVQAVEQASGGRLGLAVIDTASGERF-GWRADERFPMCSTFKFALAAAILKQVE -AGRERLDRRIPVLAGDIVANSPFCQSRVGGSASVGELCRETIIVSDNSAANLLLRTIGGP -AGFTRRLRAFGDPATRLDRWETEMSEAKRGDVRDTTQPQAMADLARRLVLGKALAPASRA -QLTAWMKDTRTSGKSLRAGLPAGWVVADKTGSGGYGTDNLVGVVWPAGRAPLVVASYITG -GTLAFEQRRPLHARVGQAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris (strain B100) TaxID=509169 RepID=B0RPW9_XANCB ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPCDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009C07049 ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGNP -PGLTRFLRGIGDTKTRSDRLEPEMNGFAPGEPCDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia flavorosea TaxID=53429 RepID=UPI0007A4BCE6 ----ATAAFADLETTHGARLGVFALDTGTGRSV-GHRMDERFPMASTFKGLACGGLLDRHR -LSSGFLDQVIRYPRHELVEYSPVTEQHVDTGMTVADLCHAAITVSDNTAGNQILKLLDGP -AGFTAFLRSLGDSASRLDRWETELNTAIPGDERDTTTPAALAADYQALVVGDRLPEPERE -QLRSWLVATTSGADRIRAGLPTDWTVGHKTGTPAYGSALDVAVAWPPGRAPLVIAVLSTK -SEQDAEPDGALLAAATRIAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. A134 TaxID=2681970 RepID=UPI0012EDC87B -----EEVFKELEDEFDARLGVYAIDTGSEQTV-AYRSDERFAYASTFKPLAAGAILQTNS ---IEDLEKVITYSEEDLVTYSPVTEKHADDGMKLEEIIEAAVRYSDNTAGNLMLEELGGP -NGLEEILRENGDETTEMDRMETELNEAAPGDTRDTSTPQALAESLQKYVLSDLLPEDKRE -LLIDWITGNETGDSLIRAGVPEGWEVGDKSGAGSYGTRNDIAVVWPPNKAPIVIAVLSSQ -DTADADYNDELIEKAAERVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. TaxID=1872122 RepID=A0A519LMF0_9BURK ---AWNDTLAGIERTAQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPASGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDGITRLDRTEPTLNEARVGDPRDTTTPLAMLQTLQKLVLGDVLTPASRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTTNSGTSNDIAVMWPPGGAPVVVTCYITA -STASSEQRDAAIAQVARAVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A3Q9KC73_9ACTN ---RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAALLKRST ---DDELNRVISYRASDLEDYAPITKRHVGKGMTLRDLIKAAVQYSDNTAANLLLDQLGGP -VGLQKALRDMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTNVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPTSGSPIVVAVLSDR -GSKDAASDDALIKDATKT----- ->[subseq from] Class A beta-lactamase n=1 Tax=Betaproteobacteria bacterium HGW-Betaproteobacteria-16 TaxID=2013707 RepID=A0A2N2TPH7_9PROT ----FHEQIAALEVAARCRLGVYIIDTATGREY-GHRPDERFMMLSSFKLLASALVLARAE -QGQDSLQRRIRYTREDLVTWSPVTEKHVGGELTLAQLCEATITTSDNTAANLILASYGGP -AAVTAFARKLGDTVTRLDRTEPELNRPSGAAPLDTTTPRAMTRTLQTLLIGNALAASSRH -TLLQWLKANTTGDKRLRAGAPADWAIGEKTGTNRT-DANDIGIAWPPGRAPLLVSAYLAE -STAPAAARDAALAGVGRLMA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lunaelactis TaxID=1535768 RepID=A0A2R4TCC4_9ACTN ---EITGQLRGLEQEHSARLGVYARNTATGRTV-LYRADERFPMCSVFKTLAAAAVLRDLD -RGGEFLAKRIRYTAEDVKDYAPITGNHLAGGMTVGELCAATICYSDNAAANLLLRELGGP -TAITRFCRSIGDRTTRLDRWEPELNSAESWRASDTTSPRAIGQSYARLTLGTVLAPQDRE -RLTGWLLANTTSGERFRAGLPAHWPVADKTGGGKYGTNNDVGITWTPDRSPIVLAVLTTQ -QEPEALADNPLIAKTATLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=A0A511ZFC6_9BACI -----EEVFKELEDEFDARLGVYAIDTGSEQTV-AYRSDERFAYASTFKPLAAGAILQTNS ---IEDLEKVITYSEEDLVTYSPVTEKHADDGMKLEEIIEAAVRYSDNTAGNLMLEELGGP -NGLEEILRENGDETTEMDRMETELNEAAPGDTRDTSTPQALAESLQKYVLSDLLPEDKRE -LLIDWITGNETGDSLIRAGVPEGWEVGDKSGAGNYGTRNDIAVVWPPNKAPIVIAVLSSQ -DTADADYNDELIEKAAERVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0013E36FB9 ---RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAALLKRST ---DDELNRVISYRASDLEDYAPITKRHVGKGMTLRDLIKAAVQYSDNTAANLLLDQLGGP -VGLQKALRDMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTNVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPTSGSPIVVAVLSDR -GSKDAASDDALIKDATKT----- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI0010BE3446 ------VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAVVWPPDRDPIIIAVMSSR -DTEDAEYNNALIAEAAKAAFK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces spongiicola TaxID=1690221 RepID=A0A2S1YWW7_9ACTN -----SRRLAELERTYSARLGVFARDTRTGRTV-SHRADELFPMCSVFKAPAVAAVLRDLD -RRGEFLAKRIHYTEKDTEEYAVITGRNLANGMTVAGLCDAAVRYSDNAAANLLLRELGGP -SAVTRFCRSIGDGVTRLDRWEPRLNSAEPWRVEDTTSPRGIAGTYSRLVLGDALSRPDRQ -RLTGWLLNNTTGTERLRAGLPDDWTLADKTGAGEYGTNNDVGIAWTPDGSPVVLAVLTTR -RHPDAAPDNRLVARIAELLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. H3C3 TaxID=2530368 RepID=A0A4R5BX89_9ACTN ---AVAKQLRGLEKTRRLRVGAYAIDTGNGQAL-SYRPDERFPFASTSKAPLCGAVLRKAR -TDPGLMDRVIRYTKDDLVPNSPVTEKRVDTGMTPAELCDAAVTVSDNTAANVLLKQIGGP -AGQTSFFRSLGDRASRQDRWEPDLNHWRPGERRDTTTPRAWAGDLRSLALGNALAPADRA -RLVGWMKDCETGGKRIRAGLPKDWTVGDKTGTGGYGSANDIAVAWPPSGAPLVIVIMTNR -PTPDGAADEEAIARTTTVLV--- ->[subseq from] Beta-lactamase n=1 Tax=Gandjariella thermophila TaxID=1931992 RepID=A0A4D4JAA5_9PSEU ---AAEAELSRLEATFGGRLGICAVDTGSGASV-RHRAGERFLMCSTFKALAVSAILRRRQ -QQPGLLDTVIRYDRSQLLPYAPVTSQHVAEGMTVSALCQAAITYSDNTAANLLLQVLGGP -PAVTAFARTLGDQLTRLDRTEPDLNVTAAGDQRDTSTPAQMAADLRVLALGDGLDPAGRD -LLVGWLKANTTGGRSIRAGLPAGWQVGDKTGSGAQGETNDIAVVWPPNHAPLVIAVYTAP -ADPKSTAGYATVARAATIVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudolabrys sp. GY_H TaxID=2292256 RepID=A0A371B0H6_9RHIZ -----AQRVAALEKKIGGRVGVYLRDITGRVLV-AHRADERFPMCSTFKFLLAAAALRRVD -QGQMSLDQVLNFGEADLLSYAPVAKANVAKGLSLGELCAAIVTVSDNTAANVILRNIGGP -QAVTAFARAIGDPDTRLDRTEPELNSAIPGDPRDTTTPQAITEDLFRLLSGNVLAPASQQ -MLENWMIASKTGLKRLRAGVPNGWSVGDKTGTGANGSANVVAIIRPGNRATLFASVYLTG -STAEADELDAVHAEIGRIAAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Acidipila dinghuensis TaxID=1560006 RepID=A0A4Q1S8C7_9BACT ---AFEQRLKVIEAGTGGRLGVGFLDPANGIRA-GWKQDERFPMCSTFKVLAVSALLSRAD -RGEEHLDRLIRYGKADVVSYSPESSRHVDTGMTVSDICRAAMTLSDNTAANLILASIGGP -AGVTAFARSLGDEVTRLDRTETSLNEAVPGDPRDTTAPGEMVSDLRKVVTGNVLSAASRA -QLVAWMEANTTGKARIRAGLAASWRIGDKTGTGDHATANDIAVLWPEGRSPVFLCVYLTE -AQVKFPDQEAAIAAVAQAAA--- ->[subseq from] Beta-lactamase n=1 Tax=Catellatospora citrea TaxID=53366 RepID=A0A419XCH6_9ACTN -----VAAFAELETRFDARLGVYAIDTGTGRTV-EHRADERFAYASTYKALAAAAVLDTTT ---AEQLDRVVHYTAADLVTYSPVTDKRVQTGMSLREIADAAVRYSDNTAGNLLLDHLGGP -DGFERSLRGIGDRTTDAARHETELNQAAPGDTRDTSTPRALATDLRAYALGDGLADDDRT -VLNDWLRGNTTGAKLIRAGVPTGWQVGDKTGAAAYGTRNDIAVVWPTDGAPIVLAILSSH -DEQDATYDDALIAQAAAAAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Blastococcus xanthinilyticus TaxID=1564164 RepID=A0A5S5CV35_9ACTN ----VSADLAQLEAEFGARLGVFAVDTGTGRTV-AHRADERFAFASTHKALSAAAVLDRTS ---PAELDELVPYAAADLVAHSPVTGQHAGAGLPLRDLLAAAVGQSDNTAANLLLARLGGP -VGLERALRELGDDVTRADRTETELNEAVPGDERDTSTPRALAADLRAFLLDGALEPADRD -LLTGWMRDTVTGATLIEAGVPAGWDVAAKSGAGGYGTRNDIAVVWPPDGAPIVLAVLSSR -DTADAEHDDALVARAAAAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF00832 -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS ---LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. 364 TaxID=2691571 RepID=UPI001318DC0C -----ARDFAALEAASGGRLGVTLLDTGSGRRF-GHRQDERFPMCSTFKFALCATVLQLAD -QGKLSLDRRLAMTTQDLLSHAPVTARHVGKDLTVRDLCRATLVTSDNPAANLLLRVVGGP -AGVTAFLRASGDDVTRNDRDEPEVNRFAPGDPRDTTSPAAMAASLQRLVLGEVLLPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ARVDDAARNDVLRQVAIIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNZ306 TaxID=2035248 RepID=A0A2M9AMG4_9ACTN ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---DRELDEVVTYSADDLIAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEDLGDDVTRMVRDEPELSRWDPDDTRDTSTPRALAEDLRALVLDDALDRRDRA -RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004BDD382 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLDKYS ---LDGLDRRVTYTRKELVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=SAR86 cluster bacterium TaxID=2030880 RepID=A0A2A4XI21_9GAMM --------AMEVERRLGARLGLAILDDESGRRW-TYQADQRFPMCSTFKVLASSAFLARVD -RGEDSLDRRVIISEDDLVSYSPLTETRVAGQMTMAEICEAALTLSDNTAGNKILESIGGP -SGLTEFARSIGDAVSRLDRWETELNEALVGDERDTTSPHAMTQTLRELLLGDTLTENSRQ -QLAHWMTANKTGDSKLRAGLPLEWTIGDKTGGGNNGTMADVAIVWPVNRPPLIVAVYMTE -TTASFDDCNAGIAEIASAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12462 TaxID=1591134 RepID=UPI0012650068 ---TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGATLNVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI000F6D8695 -----NDALATIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGRERLDARVHYAAADVVAYSPVSGPRAGNALTVGELCSATVSLSDNTAANVLMARHGGP -AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGDVLSPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTSDSGTANDIGVLWPPGGAPVLVTCYLTR -STASAEQRDAAIAQVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-4489 TaxID=1609095 RepID=A0A0X3V2E1_9ACTN ---AVTAQFTSLERKYGARLGVHAVATGTGATI-SYRADERFAFCSTFKALAAAAVLHHNP ---LSHLDQRITYTARDINSISPITQHHIATGMTLRELCDAAIRYSDGTAGNLLLRDLGGP -SQLTAYLRDLGDRTSRLDRYEPELNRDRPEDPRDTTTPRALAADYQRLLLGDALPPAKHA -LLKDWLVRNATGGRRIRAGLPPGWTVADKTGTGDYGRANDVAIIWPPHMAPLVIALQSDR -PGYSTPPQDALLAETTTHLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus atrophaeus TaxID=1452 RepID=UPI0012DA6A95 -----NKKFVQLEKKFHAKLGVYAIDTGSNKTI-AYRSNERFAYASTYKILAAAAVLKNNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -NGFEKSLKQIGDHVTKSNRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIVWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFB8316 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPARWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAEYDDKLIADATKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus indicus TaxID=246786 RepID=UPI000493465F ---AHHHDFAELEERYDAKLGVFALDTGTNQTV-SYHPDERFAYASTHKALAVGVLLQQKS ---LEDLNQRIAYTSEDLVNYNPITEKYIDTGMTLKELADASLRYSDNTAGNLILKQLDGP -AGFKKALEDIGDNTTSPERFEPDLNEVNPGETHDTSTPRALAASLQAFILGDALPPEKRE -LLIDWMKRNTTGDALIRAGVPEGWEVADKTGAASYGTRNDIAIIWPSKGDPIVLAVLSSR -DKKDAEYNDKLIAEATEKAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA70634 ------ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ -LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH -DEADANANDDLIAEAAEAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA6F032 ------ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ -LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH -DEADANANDDLIAEAAEAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces libani TaxID=68043 RepID=UPI001358CF6D ---RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST ---DDELNRVINYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP -AGLQKALRGMGDRTTRTDRTEPTLNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR -GSKDAASDDALIRDATKT----- ->[subseq from] Beta-lactamase n=1 Tax=Chromobacterium vaccinii TaxID=1108595 RepID=A0A2L2BGI8_9NEIS ----LKKAVQAEEKTLRARIGVAALDGGGGEAW-SYRGDERFPINSTFKAFACAALLAKVD -RKEAALEQTASIDQSMLAGWSPITEKRLAPQMTLDEVCQAAVSYSDNTAANVVLEAIGSP -AGFTAFMRRIGDEQTRLDRTEPDLNEGTPGDPRDTTTPNAVVASLRKVMLGDALSAASRE -KLGRWMREDRVADELLRSSLPAGWEIADKTGAGGYGSRNIIAVIWPPGRAPWLLGVYVTQ -TEASMPMRNQAIARIGAALTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Glycomyces fuscus TaxID=1407559 RepID=A0A2A6F4W4_9ACTN ---ELAREFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALSAGAVLQQNT ---LEEMEEVVTFTEDDLVDYSPITEQHVDTGMTLMEVADAAVRHSDNTAANLLLEELGGP -DGFEDALEEIGDDVTDPERIETELNAWTPGEEQDTSTPRAMAGSLREFTLGDALPEDRRE -VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGSGSHGTRNDIAVIWPSEGDPIVLAVMSSR -EAEDAEYDNALIARAAEVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Actinokineospora cianjurensis TaxID=585224 RepID=A0A421B0Y7_9PSEU ---ALVREFAQLEGKYDARLGVYAVDTGRGRAV-AYRADERFAYASTFKAFAAALVLDATT ---PQQLEESVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRRIGGP -AGLKAGLAALGDQVTSADRYEPDLSSAIPGDPRDTSTPRAMATNLRQFAVGSALSEEDQM -LLNDWLRNNTTGKDVIRAGVPRDWTVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR -DKEGAERSDALVADTARVVARVf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID2955 TaxID=2690257 RepID=A0A6B1PH58_9ACTN --------LAELEQRYGARLGVYARNVRTGRTL-AHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLNRVVHYPPLDLLPNSPRTTEHQATGMTVADLCAAAIQYSDNAAGNLLLREIGGP -AGLTRFYRSLGDRTSRLDRWEPELNTAIPGDPRDTTTPEAVAASLEHVTLGRALAPAGRE -RLVGWLKGNTTSAARFRAGLPGEWTVADKTGTGSYATANDIGVAWTTRGTPVVLVVLSTR -PTPDAAVDEKLVEEAARVMA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A410ZH92_BACIU -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKNS ---IEKLNKVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGGP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGTRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI000E1F513E ----LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLEPAMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWLPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAEAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A2A4BDE2_9BACI ----TIKKFEQLEKEYEAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLQQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKALEGIGDNVTNPERIEPDLNVVNPGETHDTSTPLALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWEVADKTGAGSYGTRNDIAILWPAKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Catellatospora paridis TaxID=1617086 RepID=UPI0012D42DEA ---SATAAFADLETRFDARLGVYAVDTGTGRFV-EHRADERFAYASTYKALAAAAVLDATT ---AEELDRIVRYTAADLVTYSPVTEKNVQTGMTLRALADAAVRYSDNTAGNLLLDHLGGP -DGFERALRDIGDQTTDAARHETELNEATPGDNRDTSTPRVLATDLRAYALGGDLADDDRT -VLTDWLRGNTTGAKLIRAGVPAGWQVGDKTGAGSYGTRNDIAVVWPTDGAPIVLAVLSSR -SQQDAKYDDALIAQAAAAAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI00046F6DFF ------VVFKQLEIKFDARLGVYVIDTETGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAVVWPPDRDPIIIAVMSSR -DTEDAEYNNALIAEAAKAAFK-- ->[subseq from] Beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=A0A268AFF1_9BACI ------ASFSSLEETYNARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREYALGDHLSADKRQ -LLIDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH -DEADANANDDLIAEAAEAAV--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces albulus TaxID=68570 RepID=Q769D6_STRA9 -------ELHELERKYGARLGIYAVNTGDGREV-GFNADERFAYASTFKAFAAAAVLRKYS ---LSGMDKVITYSRSDLIDHSPVTEKHVGTGMTLRDLCDAAVRYSDNTAANLLFDVLGGP -QGLAAALAGTGDTTTKVERREPELNQWSPGATQDTTTPRAWAGDLRAFALGDALGKDERE -QFTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR -ATKDADYDNKLIAEAASVVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella hinzii TaxID=103855 RepID=A0A0H4W2P3_9BORD ---DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA -RGEDDLSRPMRLSAADIVDYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP -PGVTAYARALGDGATRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDALPAPERE -RLRDWLMQCRTGQQRLRAGLPAGWSLGHRTGAGGHGTCNDIGVAWPTPTTPVVISVYLTE -SPLDLPERERVLAEAARILAH-- ->[subseq from] Beta-lactamase n=1 Tax=Telmatospirillum siberiense TaxID=382514 RepID=A0A2N3PWJ4_9PROT ---SLDESLAELERVNGGRLGVAILDTGTGARV-GYRADERFPMCSTFKFLLVAAVLRRVD -RHRDALERAVGIPPKPLLFNSPLTEPHARRSMSVAALCHAALTRSDNTAANLLLASIGGP -SGVTRFARSIGDKVTRLDRQEPALNESLADDPRDTTSPMAMAGNLESVLLKGVLSPASRD -QLTAWMEQNQTGLDRLRAGLPQGWRVADKTGANGEHTSNDIAVFWPEGRPPLIAAAYITQ -CPGPESKRAAMLAEIGRLA---- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AFS094228 TaxID=2033515 RepID=A0A2H3LU28_9BACI ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKNV-EFHENERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAVIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BF06339 -------AFTALEKEYTARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAKPERA -RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter alkalisoli TaxID=2591633 RepID=A0A514BQ77_9GAMM ------AQLAALERRHGGQLGVAILDAHSGRRI-NHRGEERFALLSTFKFLAAALVLARVD -RGEERLERRVVFEREALVPYSPVTEGRTGGAMSLAELCHATVTISDNTAGNLLLESFGGP -PALTAFARTLGDRHTRLDRIEPELNIVPPGEERDTTTPAAMLTSMRALLIDETLSAASRQ -QLVDWLVATSTGDARLRAGFPQGWRVGNKTGTNGN-ASNDIAIAWPPGRAPLLVSAYYDN -GELPPEQRDAVLAEVGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520HBK1_9BURK ----TRRALRRIEAAAGARLGVGILDTASGQRV-GHRADERFPMCSTFKFLAAALVLRRVD -RDLESLDRPVAIRADRLVTYSPATGRHAGGHMTMGELCEAAVTLSDNSAANLMLESFDGP -AGLTRFARSLGDDVTRLDRIETTLNEATPGDPRDTTSPAAMLGLMRELLLGRALAPASRE -RLRSWLGANTTGATSLKAGLPADWRIGDKTGAGGHGTRNDIAIVWPRTGAPVLVTAYLTG -ATLDDAAQRRVLAEVGALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia violaceofusca TaxID=941182 RepID=UPI0007A5187A ------TEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP ---PAELDRRVTYTRADLVPNSPVTEQHVDQGMTVREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAVGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAADDRD -VLTGLLRANTTGAALIRAGAPAGWQVGDKTGGGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase class A n=1 Tax=Quadrisphaera sp. DSM 44207 TaxID=1881057 RepID=A0A1H0Z1T4_9ACTN ---AAQAAFAQLEADHDARLGVYALDTGSGRSV-EHRADERFAHASTYKALAAAAVLERTS ---SADLERVVPVTDADLVTHSPIAEQRAGTGMTLREVADAAIRYSDNTAGNLLLRELGGP -DGFERSLRSLGDAVTDPERLETDLNEAVPGDVRDTSTPRALATDLHAYAVGDALPEDDRA -LLTGWLRENTTGDALVRAGAPAGWVVGDKTGAGGYGTRNDIAVLWPPSGDPVVLAVLSSR -DEPDADHDDALVADATRVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae pv. oryzicola TaxID=129394 RepID=A0A0C5V911_9XANT ---MLRAQWAEIECGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Class A beta-lactamase n=1 Tax=Geomonas soli TaxID=2496871 RepID=A0A3N7HTC8_9BURK --rEVQAQIADIERETGGQVGVFALDTHTGQHL-GHRAGERFAMCSTFKLPLAAAVFARVD -RAELSLEQSIAFSERDLVPHAPVAEKHLASGISLGECCDAMVLLSDNVAANLVLPLIGGP -AGFTRFMRTLGDPVTRLDRNEPGLNTNLLGDPRDTTTPQAMAHSLAALLTGEHLSAPSRE -RLVDLMRRCSTGLQRIRGGLPADWNAGDKTGTGSRGAVNDIAAAWPPGRRPVVISVFLSG -SALPASKLNESHTKIARIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. SLBN-154 TaxID=1985300 RepID=A0A542MZ40_9MICO ----VTDELSSLEEQYDARVGVYAVDTGTGETV-AHRADERFAYASTFKALLAAVVLQQVD -----DLDQQVAYGADALVTYSPVTEQYAGSGMSVADLAEAAVRVSDNTAANLLLDQIGGP -EGLAAALTAAGDDTTRPERREPELNTAVPDDPRDTSTPRALAETLRGFALDGGLSEDDAA -TLIDWMSGNATGDTLIRAGAPSGWDVADKSGTGQYGTRNDLAIVWPPDGEPIVVAVLTTR -GVEGATTDDALVAAAAATALE-- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus sp. TCA20 TaxID=1499968 RepID=A0A069DK38_9BACL ----ADESYADLEEEYDTRVGVFAWDTGSGKTV-SYRADERFAYASTFKALAAGAILLKES ---EEELDKIIKYSKEDVEENSPITEKHVTTGMKLSEIMDAAIRFSDNTAGNLMLKELGGP -KGFETVLREIGDTVTMADRYETELNEAVPGDDRDTSTPRALANSLHHFILTDTLSEQERT -LLTHWLHSNTTGDELIRAGVPEGWNVGDKTGAGSYGTRNDIGIIWPPDRDPIVLAIMTSR -DEKDAEYDNSLIARTTELAVQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE51_ECOLX ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEICASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces regalis TaxID=68262 RepID=A0A117MK18_9ACTN ---DVTTRLRALEEQHGARLGVFAHNIATKQTV-RYRADERFPICSLFKTLAAAAVLRDLD -RDGEVLAKRIHYTADDLVENSKETEKHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAVTRFARSLGDPVTRLDRWETELNSAEPWRTTDTTSPRAIGRTYARLVLGNALNRPDRD -LLTHWLLNNTTSANRFRAGLPKSWTIADKTGGGFYGTNNDAGIAWTEDGTPLVLAVQTTK -PEQDAAPDHALIVETAALLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Quadrisphaera sp. DSM 44207 TaxID=1881057 RepID=UPI000B872772 ---AAQAAFAQLEADHDARLGVYALDTGSGRSV-EHRADERFAHASTYKALAAAAVLERTS ---SADLERVVPVTDADLVTHSPIAEQRAGTGMTLREVADAAIRYSDNTAGNLLLRELGGP -DGFERSLRSLGDAVTDPERLETDLNEAVPGDVRDTSTPRALATDLHAYAVGDALPEDDRA -LLTGWLRENTTGDALVRAGAPAGWVVGDKTGAGGYGTRNDIAVLWPPSGDPVVLAVLSSR -DEPDADHDDALVADATRVAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces jumonjinensis TaxID=1945 RepID=A0A646KK50_STRJU ------SQLAALERKHGARLGVYALATGTGATV-AYRADERFAFCSTFKTLAVAAVLHRNP ---LSRLSERVTFTQADVNSISPITRDHIGTGMTIGQLCDAAIRHSDGTAGNLLMRDIGGP -ARLTAYLRGLGDTVSRMDHYEPELNRVPPRDPRDTTTPRAIGGDYRRLVLDDALSADKRA -LLKDWLERNTTGDKRIRAGVPRAWTVADKTGTSRYGRANDIAVVWPPGQAPLVVAIMSDR -PGQDTPPKETLIAEATARIV--- ->[subseq from] Beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=A0A1G9ZRY5_9PSEU -----DERLFELERKFDARLGVYAVATGTGRTI-AHRADERFAFCSTFKGLAAAAVLHHNP ---MSHLDTVVKYTKDDLLKNATITPRHLETGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -ARLTEYARGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGATYQKIVLGDALPPEKRA -FLRDLLERNTTGAQRIRAGVPGGWTVADKTGTGDYGTLNDIGIVWPPNSPPIVIAIMSSK -AAKDAKYDQALIAEAAAHVA--- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVT1_9BACT ----MDEKFAKLENEFDARIGIFAVDTETNQTV-AYRPDERFAYTSTFKVLAAGILLKQND ---IQELEKVITYTKDDLVTYSPVTKKHVDTGMTLLEISEAAIRKSDNTAGNLLLETLGGP -EKFQNTLRKIGDDVTNAERYETELNEFKPGNTRDTSTPRAMAINLKKFALGDLLPDVKRK -LLNEWMQGNATGDPLIRAGAPEGWKVADKSGAGTYGTRNDIAVVRPPDREPIVIAVMTRH -DTEDAKFDDALVAKAAEITL--- ->[subseq from] PSV family class A beta-lactamase n=1 Tax=Pseudovibrio sp. AU243 TaxID=1713224 RepID=UPI000D6880F6 ---ELMDTVTRLESEVGGRIGVVLQHTGSEWGI-EHREDERFPMASTFKALLCGAVLSRVD -RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNTAANLLLKRVDGS -EGLTRFLRGLGDRVTRLDRNEPALNEAKHGDSRDTTTPSAVLKTLDRLLFEDVLLPSSRA -QLQQWMVDDKVADELIRKHLPKGWRIADKSGGGQNGSRGIISVIWPETGKPYLASVYMMG -SDASFRQRNAVIAAIGKAMIE-- ->[subseq from] Beta-lactamase TEM n=1 Tax=Labrenzia sp. OB1 TaxID=1561204 RepID=A0A161YYK8_9RHOB ----LASAVDDIAARLPARVGVAVIDTQSGTRW-SYRGDERFPSNSTFKAFLCAALLDAGA -RGVADPDRSVTIRRSDIVSYSPVTEKHIDGNFTIRDLCEITVTISDNTAANFVLKEIGGP -QAVTDYLRGIGDAVTRVDRMEPDSNTGIPGDDRDTTSPNAAAETLEKLVLEKTLPDDARR -ALTGWLMGNKVGDATLRAGLPDGWRIADKTGAGANGSRNNIAVIWPEGRKPVVIAVYITG -TTASLEARNSAIAEIGAALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora cianjurensis TaxID=585224 RepID=UPI000EB36AE4 ---ALVREFAQLEGKYDARLGVYAVDTGRGRAV-AYRADERFAYASTFKAFAAALVLDATT ---PQQLEESVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRRIGGP -AGLKAGLAALGDQVTSADRYEPDLSSAIPGDPRDTSTPRAMATNLRQFAVGSALSEEDQM -LLNDWLRNNTTGKDVIRAGVPRDWTVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR -DKEGAERSDALVADTARVVARVf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PTY087I2 TaxID=1819298 RepID=A0A1B9EXX2_9ACTN -------DFKELERKFDARLGVYAIDTGTGREV-AHNDRARFGYHSTFKALQAAVVLSTYS ---LDGMEKRVTYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -KGLDASLEKLGDDITRMDREEPELSGWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPKGWVVGDKTGTGGYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDRLIAEAATVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID161 TaxID=2690251 RepID=UPI001370B1F5 --------LAELEQRYGARLGVYARNVRTGRTL-AHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLNRVVHYPPLDLLPNSPRTTEHQATGMTVADLCAAAIQYSDNAAGNLLLREIGGP -AGLTRFYRSLGDRTSRLDRWEPELNTAIPGDPRDTTTPEAVAASLEHVTLGRALAPAGRE -RLVGWLKGNTTSAARFRAGLPGEWTVADKTGTGSYATANDIGVAWTTRGTPVVLVVLSTR -PTPDAAVDEKLVEEAARVMA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B8026A ----SDREFAKLEEKYDANLGIYALDTGTNKMV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALAASLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium shewense TaxID=1761772 RepID=A0A1C3XJV3_9BRAD -------ELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYGKPDLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPADWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG -GAPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3D5JRI1_9GAMM ----TATDLAALEAASGGRLGVTLLDTASGARI-GHRQDERFPMCSTFKFVLCAAVLHQAD -SGRLSLDRRVPVRQQDLLAHAPVTGRHVGKDLSVRDLCRATLITSDNPAANLLLGVIGGP -PAVTGFLRAHGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRLLLGDVLSAPARQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGQDTTNDIAILWPLGGAPWVLTSYLQG -ARVDDAGRNEVLRQVAVIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas TaxID=338 RepID=UPI00141B05FE ---MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -EGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMVSTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM66233 TaxID=2654677 RepID=UPI0012E9F75C ---TTADALRALEREFDARLGVYAIDTGTGREV-AYRDNERFAYASTFKALAAGAVLRQHS ---PNGMNQVIKYSRNDLVAHSPVTKKYVTTGMTLRELCDAAVRFSDNTAGNLLLDALGGP -KGLNSALRDLGDDVTRVERREPELNQWAPGATRDTSTPRALASDLRALVLGDALGETERT -QLARWLRTNTTGAELIRAGMPKGWVVGDKTGAAGYAVRNDIAVVWPADAAPIALAITSNR -GEEDADYDNMLIAEAASVVAR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Frateuria terrea TaxID=529704 RepID=A0A1H6VII2_9GAMM ----PAARLAALEKQHGGRLGVAILDTANGRRV-AYRGDERVLMCSTFKVLAVAAVLARVD -RGDEQLSRRIVFGRDTLLGHAPVTRLHTGAPMRLEDLCAAAITVSDNTAANLLLATLGGP -PAVTAFVLGLGDRVTRLDRTEPELNVTRPGDLRDTTTPHAAVDTLRQLLLGEALSATSRA -RLLGWMRGCLTGTDKLRAGLPDGWSAGDKTGSGAQGESNDVAILFPPARPPLLVTAYYTA -PAAEAQLRSAVLAEVGRIAA--- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA04A6A ---AVQQKLAALEKSSGGRLGVALIDTADNTQM-----------CSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces violaceoruber TaxID=1935 RepID=A0A1V0UKV0_STRVN -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDRRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudogulbenkiania ferrooxidans EGD-HP2 TaxID=1388764 RepID=U1BQ45_9NEIS ----LKKAVQAEEKTLRARIGVAALDGGGGEAW-SYRGDERFPINSTFKAFACAALLAKVD -RKEAALEQTASIDQSMLAGWSPITEKRLAPQMTLDEVCQAAVSYSDNTAANVVLEAIGSP -AGFTAFMRRIGDEQTRLDRTEPDLNEGTPGDPRDTTTPNAVVASLRKVMLGDALSAASRE -KLGRWMREDRVADELLRSSLPAGWEIADKTGAGGYGSRNIIAVIWPPGRAPWLLGVYVTQ -TEASMPMRNQAIARIGAALTQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CC53 TaxID=1906740 RepID=A0A1S2K8W2_9ACTN ----TTGRLRELEREHGARLGVFAYDTGTHRMV-AYRQGERFPMCSLFKPLAAAAVLRDLD -RDGEFLARRIPYGVEDLEPWSPVTKDHVGAGLTVEELCDAAIRHSDNTAANLLLRELGGP -TAVTRFCRSAGDGVTRLDRWEPELNSAEPWRETDTTTPYAIARTYGRLVLGGLLERRDRE -RLTGWLLSNTTSTERFRKGLPADWVLGDKTGGGSYGTNNDAGVTWPPGRPPIVLAVLTTK -PEPAALPDNPLVAEAARIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. L36 TaxID=1747221 RepID=UPI00131E8C47 -----VARLAALERRHGGRLGVSILDTGTGRRV-SHRGDERVLMCSTFKVLAVAAVLARVD -RGIEQLDRRIVFGNDVVLSYAPVTSKHVGAPMSVAELCEATIELSDNTAANLLLSSMGGP -QAVTKFVRGLGDPVTRLDRIEPDLNVGHAGDLRDTTTPNAMLATLQKLLLGDRLSSASRA -QLAAWMRACRTGIDQLRSGIPADWTAGDKTGSGAGDETNDVAVLLPPNRAPVVVTAYYVA -PVADVATRHAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Fastidiosibacteraceae bacterium SYSU SYW-6 TaxID=2219059 RepID=UPI000E6526BE ---SIHNNFKALEKQYGGQLAISAIDTSNNHAV-DYHADKRMPMCSTFKLMLVAAVLKKSV -DDPMLLEKKIVYTQKDMVNYSPYTQKNLGKGMTISALCHAAM-LSDNTAANLLLKQLGGL -KKLNQFARSIGDMTFRLDRYEPYLNTAIPGDKRDTTTAKAMSQSLDKIVLGDVLPTMQRD -LLIKWMQTNTTGDKRIRAGVNKSWIVGDKTGTGDYGTTNDIGVIWPNKCKPIVISVFYTQ -AKQDAKAQDAVIQKATSVAVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4G2X4_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKD------------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=A0A0C2AT65_9ACTN -----EGAFGGLEQEFDARLGVYALDTGSGRTV-THRPDERFVYASTCKALLAGAVLDRYS ---LRQLERLVRYDRDDLVSDSPVTEKHVGTGLTLRELCDAAIRYSDNTAANLLFRQLGGP -RGLQTALRGLGDNVTRCDRYEVALSDAVPGDVRDTSTPRALAGGLRAYVLGATLPPDRRA -VLTDWLKRNTTGATTIRAGAPDGWQVGDKTGTGGYGTRNDIAVLWPPAAAPVVLAVMSRR -DTKNAERDDALIARAAKIAL--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. IMTB 2501 TaxID=1776340 RepID=A0A1R0MA61_9ACTN -----EAELADLERRHGARLGVYGRNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --DRAPLDAVIHYPPHDILPHSPRTEEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFFRSLGDGTSRLDRWEPELNTALPGDRRDTTTPEALGRSFERLTLGRALARADRA -QLVTWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTTNDIGVAWTTRGTPVLLTVLSAK -VVQNAAADDGLVAEAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillaceae TaxID=186817 RepID=UPI000479286E ---DLDEAFTEIEEAFDARLGVYAIDTGTNQSV-EYNPDERFAYSSTYKLLAAAFVLKQND ---LQDLEEVVTYSKDDLVTYSPVTEKQVDTGMTLSEISEAAIRESDNTAGNLLLDALGGP -DNYKQALRDIGDDVTQPERYETELNAFSPENKRDTSTPRAMANNLRKVALGDFLPKEKQE -LLIDWIKGNATGDALIRAGKPEGWTVGDKSGAGSYGTRNDIAIVWPPGREPIVMAIMSRH -KTEGAEYDDELVAKAAEATLNAf ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. CFBP 7912 TaxID=1891621 RepID=UPI000CEEABD5 ---MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -QGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTTFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces niveus NCIMB 11891 TaxID=1352941 RepID=V6JJL3_STRNV ----IKRAFADLERKFDARLGVYAIDTGSGRSI-THRPDERFAFASTCKALLAAVMLEKNS ---LRQLDRLVRYDRDDLAGYSPITEKHLDTGLTLRELCDATVRYSDNGAANLLFHEIGGP -KKLEAALVSIGDRVTRCDRYEDALSEALPGDLRDTSTPRALATDLRTYVLGDRLPADKRD -VLTDWLKRNTTGDKVIRAGAPAGWVVGDKTGTGGYGTRNDIAIVWPPKAAPIAIAVMSRR -DEKDAEPDDALLAGAAKVTLDAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus vulgaris TaxID=585 RepID=G8A3S3_PROVU ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRILYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A4U0M9K3_BACME ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALEKIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKGAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001117079B ----------------------------------LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila subsp. keratiniphila TaxID=227715 RepID=A0A1W2LMD6_9PSEU ---QFHDRLMELEKKYDARLGVYALDTGDGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVRYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLAADKRD -FLRDLLQRTVTGAGRIRAGLPPGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -AAKDAPYDEALLAEAAKYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=alpha proteobacterium AAP38 TaxID=1523418 RepID=A0A0N0K9L2_9PROT ----MREAMAALERARGGRLGVALLDTKTGAAM-NWRGDERFAMCSTFKFLLAGYILSRVD -AGQERLDRMVTFGKHELVTWSPLTEPHVDKGMSINDLCQAIMIQSDNTGANVLMRESGGP -TALTAFLRAAGDGVTRVDRIEPAMNVVGPDDVRDTTTPVSMLGLMRSLLLGEVLTPASRQ -RLTDWMIDNRTGKERLRAGLPAGWRIGDKTGTYD-AFNNDIAILWPPAGGPLLLTSYYAN -PTADKAVRNIVHAEVAAIVAKAy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI0010C4ABC7 -------AFKKLERSYDARLGVYAIDTGTGHEV-AYRDGERFGYASTFKALEAGAVLQKVK ---LGGLDRVIMYSKDDLIDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDAMLEKMGDDVIQMERREPELSRWVPGSTRDTSTPRAMAKDLRAFVLGDVLGDGERT -QLTKWLRTNTTGDALIRAGVPKDWQVGDKTGSGSYGGRNDIAVVWPPDSAPIVMAIMSNR -GDKDATSDDKLIADAAHVVADQ- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia niigatensis TaxID=209249 RepID=UPI00031D0453 ------AALRALEQQHGARAGVVAIDTGTGKTV-GYRQDERFAFDSTFKPLACGALLHAHP -LGSGFFDQVIHFTPDKLVANSPITSTRVDTGMTVAELCQAAITHSDNTAGNQILELLGGP -PAVTAFLRSIGDQTTRMDRWETELNTNIPGDERDTSTPAALADDYRKLVLGDALAEPERT -QLTAWLLANTTGDARIRAALPADWKTADKTGSGDYGTANDIAVIWPAGGAPLVILVLTTK -PDQAAAADNPLVAALAKEAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Novispirillum itersonii TaxID=189 RepID=UPI0012DEDF3E ------TKAAEIERTLGARVGVAVIDTASGQIW-EYRGNERFPLNSTFKALACGTLLQMAQ -RQELDLSQSVPVEAGAIVSYSPVTEKRVGSAMTLSDLCAATMTYSDNTAANLVLRAVGGP -VALTEALRRIGDPVTRIDRWEPDMNEATPGDLRDTTTPLAMARTLQSLALGTVLPGESGD -LFRQWLKDNQVSGPLLRAGLPGGWTVGDRTGAGGHGSRSVVAVVWPPQRKPLVVTAYLTQ -TKASMDQRNAALASLGREVAK-- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas cervicalis ATCC 49957 TaxID=525371 RepID=D5RSM8_9PROT ---EFARRMAEIEARSGGRLGVALLDTGSGFRA-GHRAAERFPMASTFKLLLAGAVLRRVD -EGKERLDRVIRFTRDDLVPYAPVTGPAAGGPLTVAALCEATVTLSDNPAANLLLDTVGGP -AGLTAFLRGLGDATTRLDRTEPALNEGRPGDPRDTTTPDSMAFLIRALALGDALRPASRE -RLMGWLLGNRTGDAQIRAGLPQGWRAAEKTGSNSAGIANDVGLLLPPGRAPVLLAAYLTE -ARIAAAERPALLAEVARAAVR-- ->[subseq from] Beta-lactamase n=2 Tax=Zoogloea ramigera TaxID=350 RepID=A0A4Y4CNX8_ZOORA ----ILAQMQTLEAEARGRLGVHVLDTADGATY-GYRADERFQTLSSFKFLASALVLHRVD -RGLESLDRRIPITPADIIPWSPVTERHVGDPMSLAALCEATITTSDNAAANLILDSYGGP -AALTAYLRTLGDSVTRIDRREPELNVKHPDEPMDTTTPRAMVMNLHKLVLGDALSAASRA -LLTKWLEGNTTGGKRLRAGLPDTWRVGEKTGTFQS-DANDSGVVWPPERAPLIVSAYLAD -SAVDSAARDATLAEVGRVV---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces decoyicus TaxID=249567 RepID=A0A0L8M3J6_9ACTN ---RAAKALAQVERRFHARLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAGVVLKRST ---DDELNRVIRYSASDLEDYAPITKRHVDQGMTLRDLVKAALQYSDNTAANLLLDQLGGP -AGLQKALRAMGDATTRVNRTEPTLNEAKPGDTRDTSTPRTLGTDLRGFVLGDVLPEGRRQ -LLTGWLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPASGAPVVVAVLSDR -GSKDAASDDALIKDATKA----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lonarensis TaxID=700599 RepID=UPI001438F73A ---SAASTFEQLEEEFDARLGVYALDTGTGEEV-EYRSDERFAFASTFKAFAAGALLAQYG ---LDGIDTTVAYDKADLISHSPVTERFTGEGMTLRDLAAAAVRQSDNTATNLLFDALGGP -TGLQAALRGIGDETTNVDRLETELNEATPGDDRDTSTPRAMAETLNAFVFGDVLDAQESD -QLVEWMTTNTTGATLIPAGVPDSWTVGDKSGAGGYGTRNDIAVLWPEEGEPIIMAVLSSR -DEEDATYDDALVARAATSA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ZL-24 TaxID=1933029 RepID=A0A2S3XXG8_9ACTN ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGIRNDIAIVWPPGAAPIAIAVLSRR -DVKDAESDDALIAGAAKVALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SPMA113 TaxID=913267 RepID=UPI00085305F9 ---AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -RGLDTILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLDKGERS -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSIMSYR -GDKDADYDEKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF32C95 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGL -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTGDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase CTX-M-2 n=1 Tax=Xenorhabdus doucetiae TaxID=351671 RepID=A0A068QVK4_9GAMM ---EIMHQLAMLEKNANGRLGAVLIDTSDHSTL-SYRANERFPLCSTSKLMAVSAILKQSE -TDAHLLHQRIHYQPSDLVEYSPITEKHLKEGMTLAELSAATLQYSDNTAMNLLLNQLNGP -DGVTTFARTIGDHDFRLDRQEPELNTVVPGDERDTSTPQAMANSLSHLALGNALATTQRE -QLVAWLKGNTTGSTSIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPPKRAPLVLVTYFTQ -PDKQAHARPDVLATAARIMTQNf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI000A02D838 -----TATFADMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP -EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERD -QLATWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK -PDQNAEPSNDLVAEATKAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus psychrosaccharolyticus TaxID=1407 RepID=UPI0002D71442 ---KPESKFAKLEEKYDAKLGVFAMDTGTNRTV-AYHPDERFAYTSTHKALAVGALLQQNS ---IEDLNQLIFYTREDLVNYNPITEKYVDTGMTLKELSDASLRYSDNTAGNLILNQIGGP -AGFKQALEEIGDTVTNPVRYEPDLNEVNPGETHDTSTARALAASLQAYTLGDTLSAEKRE -LLLDWMKRNTTGDALIRAGVPKGWVVADKTGAGLYGTRNDIAIIWPVKGDPIVLAVLSSR -DKKEAEYNDKLIAEATEAAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium liaoningense TaxID=43992 RepID=A0A151FNV2_9BRAD -----PAELEAYERDTGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSTQSRL -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVVWPKPDAPILIAAYTQG -GTPNAAQIATLFAQIGRMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia niwae TaxID=626084 RepID=UPI0009FCB7D0 ------ASFHEIETRHAARLGVYAVDTGSGRTV-VHREAERFPMASTFKGLACGALLRDHP -LSTGYFDQVIHYARSELVENSPVTEKRADTGMTVAELCDAAITVSDNTAGNQVLKLLGGP -EGFTAFLRSIGDTTSRLDRWETELNSAVPGDERDTTTPAALAADYRDVVLGDVLAEPERA -QLKSWLIASKTGADRIRAALPAAWTVGNKTGSPAYGSALDVAVVWPPGRSPFVIAVLSTK -AEQNAEADNPLVAEAARAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=A0A1A9QJB7_STRA9 ----ATGRLRALERRHGARLGAVARNTVTGATV-LYRSDERFPMCSTFKTLAAAAVLRDLD -RHGEVLAKRIRYTAADLVPNSKKCEENLATGMTVAELCDATIRFSDNTAANLLLRELGGP -AAVTRFCRSLGDTTTRLDRWEPELNTCEPWRVEDTTTPAALSGTYERLVLGDALNRGDRE -RLTGWLLGNTTSTHRFRAGLPEDWRLADKTGGGAYGTNNDAGVAWTPDGTPVVLVVLTTK -PEQEAAADDLLVARAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI00119D2AF7 -----NHHFAKLEEKFDAKLGVFALDTGTNQTV-TYHPDERFAYASTHKALAVGALLQQKS ---IEELNQRITYTREDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILKQLGGP -TGFKKALEEIGDNVTNPERFEPDLNEVNPGETHDTSTPRALATSLQDFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWLVADKTGAGSYGTRNDISIIWPSKADPIVLAVLSSR -DKKDADYNDDLIAETTVEVM--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SLBN-192 TaxID=1119093 RepID=A0A542U454_9ACTN ----VTARLRELEQEHTARLGVYGRNLRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQEYVTKYSPITEDHVAIGMTVGELCDATIRFSDNTAGNLLLKELGGP -RAVTRFSRSVGDRITRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGSALEPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax TaxID=12916 RepID=A0A2G6S8D5_9BURK ---AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSPMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQDGAPVLVTCYLTR -SKASPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. GPE 39 TaxID=1583099 RepID=UPI0005F2C9A0 ---ALQQRLAEIERRSGGRLGVYLLDSGTGQRI-GRREQERFPLCSTFKFLLVAAVLQRVD -RGEMGLDQRVRVRAVDVVSYAPVTKPHVGGTLSVDALCRAAMIFSDGGAANLLLRLVGDP -PGLTRFLRAHGDTQTRSDRNEPSMNGFALDDPRDTTTPAAMATTMRTLLLGDVLQPASRQ -RLIDWMIDNRTGDGCLRAGLPAGWKIGDKTGNNGSDSRNDIAIVWPPGRAPLLLTAYLNM -ATVDSDARDAALKAVAQAVVAWw ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium cajani TaxID=1928661 RepID=UPI0012F89EFB -------DLETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSRPGDARDTTTPAAMAGNLRRLVTGEALSAASRA -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYVQG -GTPSTAQIAATFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B72100 ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429DW79_9PSEU ---QFHDRLMELENKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD -FLRDLLQRTVTGAGRIRAGLPPGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -SAKDAPYDEALLAEAAKYVVEE- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. QZS01 TaxID=2213226 RepID=A0A3Q9JHA7_9PSED ------DKIKEIESQFNARVGYVQLDFSNGLLIdGYRYQERFPMMSTFKVLLCGAVLSRVD -SGLEQLNRRIRYRQSDLIEYSPVTKEHLSEGMTVAELCNATITMSDNTAANLLLSSIGGP -KELTKFLRKMGDPITRLDRWEPMLNESLPEDERDTTTPESMSKTLFTLLKGKTLTTNSRQ -QLIDWMEADKVGEPLLRSVLPKGWFIADKTGAGEHGSRGIIAILGPDEKPSRIVIIYLTG -SHTTMDERNKQIAEIGASLIKRw ->[subseq from] Beta-lactamase n=1 Tax=Hazenella coriacea TaxID=1179467 RepID=A0A4R3L7J1_9BACL ---TVTDDFAKLEEEFDARLGIFALDTGTKQTV-TYRADERFAYTSTHKALAVGALLQQKS ---ISDLNQRITYSQDDLVTYSPITEKYVNQGMTLKEICDASLRYSDNTAGNLILEQLGGP -SGFKKSLVAMGDDVTNPVRIEPELNDVKPGETHDTSTPRALATSLQAFTIGDTLPTEKRE -LLVDWMKRNTTGDALIRAGVPKGWEVADKTGGGFYGTRNDIAILWPPKGDPIVLAILSDR -DEKDAKFDDKLIAQATKEVID-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2QLH9_9PSEU ---QYHDRLLELEKKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -GELTAFTRGLGDTVTRMDRIEPLITEATPGDPRDTTTPRAFGTDYQRILLGDTLASNKRD -FLRDLLQRNATGADRIRAGLPSGWTIADKTGTGDYGTLNDIAVVWPPGKPPIVMAVMSSK -AAKDAPYDQALLAEAAKYVVE-- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. Intermedium TaxID=1379677 RepID=A0A077QC52_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYRAHERFPLCSTSKMMTVSALLKKSE -TDEGLLNQRIHYQQSDIVEYSPITEKHLKDGMTLADLSAATIQYSDNAAMNLLIDQLGGT -HDVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMANSLYKLALGNTLAATQRT -QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ -PNKDAEAHPDVLAAAARIMTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5639 TaxID=1463867 RepID=UPI00055E7D05 ---KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS ---LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP -KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALATDLRAFVFGDVLPGRKRE -VLTDWLKRNTTGDKLIRAGAPSGWEVGDKTGNGGYGTRNDIAVLWPPKGDPVTLAVMSRR -DTRNAEHDDALIAEAAEVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces purpureus TaxID=1951 RepID=UPI0007C676C4 ---AITARLRRLERQHSARLGVFAHHTGTGRTV-AYRADEHFPICSVFKTLAAAAVLRDLD -HDGSFLARRIRYTAPYVTKWSPITGKNLAQGMTVAELCDATICHSDNTAANLLLTELGGP -TAITAFARSIGDRTTRLDRWEPELNSAEPWRETDVTTPGAIGLTYARLTLGNVLEPADRQ -RLTGWLLANTTSGERFRKGLPADWTVADKTGGGRYGGNNDVGIVWPPGQAPIVMAVFTTK -HKEDAPADNPLVAKTAALLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Cohaesibacter sp. ES.047 TaxID=1798205 RepID=A0A285M7T5_9RHIZ ----LKTTVSTWEGKLDARIGVILRDGSSDWEI-SYRADERFPMASTFKTLLCGAVLRRVD -DGQESLAELVTYSKKDLLSWAPITEKHVTGGMKLADLCEAAITMSDNTAANLLLSRVKGP -EGLTDFLCQIGDTTTRLDRWEPELNEATPLDPRDTTSPRAIATSLDKLLFGNALQPASAQ -HLKQWMIDDKVADKLIRPHVPNGWIIGDKTGAGGNGTRGIVAFIQTPEGQTYLAAIYITQ -TKAAFELRNQVISDIGKAIIS-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=A0A4R4P0N3_9ACTN ---EVTKQLTRLERTRHARIGAFAIDTGTGRTV-SHRADETFPFASTFKAMACGAVLRKAR -QAPGLLDKVIRYTEADLVDYSPVTEKHVGTGMTVADLCHAAITQSDNTAGNLVLRQIGGP -AGLTAFLRSLGDRVSRSDRWETALNDWRPGERRDTTAPRPWADDLRALTTGNALVPADRG -RLVGWLKATVTGDKRIRAGLPKSWTVGDKTGTGGYGTANDIAIAYPKAGAPLIIVITTNK -RTPDAEADDKAIARTAGILA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L9E9_9ACTN ---DAEADFALLEEEFDATLGVYALDTGSGEAV-EYRADERFGYASTFKVALFGALLEQTT ---PEEMEKVVTISEDDLVNWNPVTEERVGDDMSLLELGDAALRYSDNAATNLLLEELGGP -EALDAALEEIGDDVTSVDRIEPELNEGTPGDERDTSTPRAMATTLEAFTLGDVLPEEESD -LLVEMMRGNTTGDDLIRAGVPEDWEVGDRTGAGGYGIRNAIAVAWPPEGDPIVLAVMSSR -DQEDAEYDDALIAQAAEVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=A0A223QDT8_NOCDA ------REFERLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTYTEEDLVDYSPITEQHVDTGMTLMEVADAAVRHSDNTAANLLFEELGGP -DAFEDELEAIGDDVTDPERLETELNDWTPGDTSDTSTPRAMAGSLREFTLGDALPEDRRE -VLNNMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVIWPPEGDPIVLAVMSSR -DEEDAEYDNALIARAAEVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. 171095_106 TaxID=1286363 RepID=UPI00048E4865 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKGAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BA599B1 ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKGAEYNDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNY243 TaxID=1169161 RepID=UPI000377C70A ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALGKRDRA -RLTEWLRTNTTGDTLIRAGVPGTWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus TaxID=44249 RepID=UPI000737BBB2 ------VVFKQLEVKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSLKLLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTKDAEYNNALIAGAAKAAFK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sviceus ATCC 29083 TaxID=463191 RepID=B5HXK1_9ACTN ---DITARLHALEERYDARLGVFAHHVTTGRSV-RHRADERFPMCSVFKALAAAAVLRDLD -RDGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELADVAITFSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALDRRDRQ -LLTHWLLNNTTSVNRFHAGLPKTWTIADKTGGGSYGTNNDVGVVWTEDGDPIVLSVLSTM -PAQDAVRDDALVAEAAAVVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNB091 TaxID=1169156 RepID=UPI0003812B2A -------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDGVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALGRPERA -RLTQWLTTNTTGGELIRAGVPEGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -ADADADYDNTLIAKAASAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. ERG5 TaxID=1381597 RepID=UPI0009E0A735 ---ELAAAVRACETASGGRLGVAILDIATAARF-SHRGDERFPMCSTVKLPLAAAILRAVD -QRRTRLDNRVPVSAGDILGHSPFSETRVGGTASLAELCEATLTLSDNAAANLLLPVIGGL -PGLTRFARTLGDTATRFDRNEPDLNEGKPGDPRDTTTPVAMLGLLNRMLLGSALSRAQRA -RLTRWMIGNHTGDNRLRAGLPAGWRVGDKTGTGGHGSNNDIAILWPPARAPLLVTSYLTG -SPLSSAASEAIHARLARSIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2664 TaxID=1463842 RepID=UPI0004C4F5EE -------EFYELERKYGARLGVYAVNTGDGREV-AFNADERFAYASTFKAFAAAAVLRKYS ---LSGMDKVIKYSRSDLIDHSPVTEKHVETGMTLRDLCDAAVRYSDNAAANLLFDALGGP -QGLAAALAETGDTTTKVERREPELNQWSPGATQDTTTPRAWAADLRAFVLGDALGKDERE -QLTQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSNR -GTKDADYDNKLVAEAASMVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. NCIMB 12038 TaxID=933800 RepID=A0A1Y5LGP4_9NOCA --qSLDAKIGALEAQYSTRIGVTAVDPATGAVY-SHRGDERFAMCSTFKAYASAAVLRRIE -DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDVGDESTRLDRWETELNTAFRGDPRDTTTPAGLAQGFRALLLGDALDPASRD -QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. MA-N2 TaxID=1101188 RepID=UPI0004BC533A -----TEPFSGLEKEYDARLGVYGIDTGTGKTV-MHRADERFAYASTSKALLAGAILAKTS ---TPELDQIIRYTSGDLVSYSPVTEKHLDTGMPLREVIAAALQYSDNTAANLMFKQLGGP -KGLDESLKTIGDTTTHVDRTEPELNEAVPGDIRDTTTPKALGTDLAAYTLGNALTSEYRA -LLTGWLKGNTTGGNLIRAGVPSGWTVGDKTGGGSFGTRNDIAVIWPTTGAPIVLSIMSSK -STKDAKYDDALIAAATRAAIA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SX83_9BACT ------EAARQAEAQLDARVGLAVYDTGSGANW-LFNADESFPMGSTFKVLACGVLLARAD -AGDEDLDRFVEIVQTDLVTYSPVTETWVGRNVSLGEICAATMRTSDNTAANKVLEALGGP -GSLTAFLRSLGDQTTRLDRWETDLNEGTPGDPRDTTSPAAMAASFQKFVLGDVLSTSSRE -TLTDWLLGNEVGGPLLRAGLPEDWRIGDRTGAGGHGSRGIVAVLWPPGRAPLIAAIYLTE -TQATLEGRDAAIAAIGRAIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI98-10 TaxID=1522763 RepID=A0A3N6HY84_9ACTN -----GRAFSALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREHG ---MGGLERVVRYRREDLVEHSPVTEKHVATGMSLGDLCDAAVRHSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWSPGATRDTSTPRALAEDLRAFVLGDALGKPERA -RLTRWLRDNTTGGELIRAGVPQGWTVGDKTGAGSYGTRNDIAVVWPPGAAPLVLAVLSNR -EDADAAFDNTLIARATSAAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces caeruleatus TaxID=661399 RepID=A0A117RHV9_9ACTN -haATTDRLRELESRHGARLGVFAHNLATGQTV-HHRADERFPICSLFKTLAAAAVLRDLD -RDGEVLGKRVYYTADDVVENSDITEDHVATGMTVAELADAAIRCSDNTAGNLLLRELGGP -CAITRFARSLGDPVTRLDRWEPELNSAEPWRRTDTTTPRAIGRTYARLVLGDALNRPDRD -LLVHWLLNNTTSVNRFRAALPETWALADKTGGGSYGTNNDAGIAWTDDGTPLVLVVQTTK -PEQDAAPDHALIVETAKLLTE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Xenorhabdus cabanillasii TaxID=351673 RepID=A0A3D9UJQ3_9GAMM ---QIINQLVALEKSANGHLGVFLINTADNSTI-GYRANERFPLCSTSKFMTASALLKKSE -KDGKLLNQRINYKQSDVVEYSPITEKHVESGMTLAELSAATLQYSDNTAMNLLLDQLDGP -RGLTKFARTIGDNEFRLDRKEPELNLVKPGDERDTSTPQAMAKSLYKLTLGNVLATNQRV -QLVEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNRAPLVLVTYFTQ -PGKNAKARRDVLAEATRILTQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK215 TaxID=2512127 RepID=A0A4R3RTP4_9ACTN ----FAADFRRLEHTYGARLGVYAVDTGSGREV-AHNATERFAYASTIKAFAAVAVLRRHS ---PHGMEKVVRYAKGDLIAHSPVTEKHVGTGMTLRDLCDAAVRHSDNTAANLLFDAIGGP -KGLEAALREAGDTTTRVERREPELNQWAPASTRDTTTPRAFAADLRAFVLGDALGGPERA -QLTSWLRTNTTGDELIRAGVPKDWVVGDKTGGGGYGVRNDIAVLWPPGRAPVVMVIMSNR -GTEGAAYDNELIARAASVAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00124E3E89 ---AVTKQLKALEKSRKDRIGAYAVDTGTGRFL-AYRADERFPFASTFKVMACGAVLRKAR -RDPGLMSRVIHYSKSDLVDYSPVTEKHVKTGMTVAALCKAAITQSDNTAGNLVLRQIGGP -AGDTAFLRSLGDRVSRHDRWETDLNIWRPGELRDTTTPRAWAGDLRALTAGGALVRADRD -RLIGWMKQTVTGDHRIRAGLPKGWTVGDKTGTGSYGAANDIAIAWPPSGAPVIIVITTNR -LTPDGTADEPAIAKTASILAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BpilaLS-43 TaxID=1839778 RepID=UPI00081BC4C8 ----TAGAFEKLEDKYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYT ---VGGTDRLITYSGDDVVPDSPVAEKHVDTGMTLDALCDAAVRYSDNTAANLLLRQLGGP -EALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA -RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGTGGYGVRNDIAVLWPPDRAPVVVAVMTSR -DREDDTHDNRLLAEAASVVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus toyonensis TaxID=155322 RepID=UPI000BF1615C -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS ---LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMRDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATQVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00055F42B6 ---DITARLHALEERYDARLGVFAHHVTTGRSV-RHRADERFPMCSVFKALAAAAVLRDLD -RDGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELADVAITFSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALDRRDRQ -LLTHWLLNNTTSVNRFHAGLPKTWTIADKTGGGSYGTNNDVGVVWTEDGDPIVLSVLSTM -PAQDAVRDDALVAEAAAVVAR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. M7 TaxID=255705 RepID=A0A370VL80_9ACTN ---DVRARLRELERGHGARLGVYAHNVVTGRTL-THRADERFPVCSLFKPLAVAAVLRDLD -RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP -TAVTRFARSIGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGGSYARLVLGDALDARDRA -RLTHWLLHNTTSVNRFRAALPPPWTVADKTGGGSYGANNDAGVVWTEEGVPLVLAVMTTR -PEQDAAYDHALIVEATRLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mutomycini TaxID=284036 RepID=UPI000818AC91 ----TEGAFVELERKYGARLGVYALDTGSGRTV-THRSDERFAYASTCKVLLAGAVLDRNS ---LRRLDRLVRYSRDDLISNSPITERHVATGLTLRELCDAAVRYSDNAAANLLFRELGGP -RGLQDALRALGDDVTRCDRYEVALSDAVPGDLRDTSTPRALVDDLRAYVLGSALPADKRA -VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAIAWPPGAAPIALAVLSRR -DAKNAESDDALLARAAEVAF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptacidiphilus pinicola TaxID=2219663 RepID=A0A2X0IER5_9ACTN --qAVEGRLRALERRHDARLGVFAYDTGTGRSV-RYRADELFPICSTVKTIAVAAVLRDLD -RDGRFLAKRIHYTAAYVTDYAPITGANVARGMTVAELCAAAIEYSDNGAGNLLVRELGGP -QAVTRFCRSVGDRVTRLDRWEPALNSAEPWRVTDTTSPRAVARTYARLVLGDVLTARKRE -LLTGWLLANTTSAHRFRAGLPKGWTVADKTGTGDYGTTNDVGFTWPPGRRPIVLSVLSTQ -HDATAPADEPLVADAAAAVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus polymyxa TaxID=1406 RepID=E0RMI1_PAEP6 ------VVFKQLETKFDARLGVYVIDTGTGKEV-TYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHRDTSTPNALANSFKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDRKPIIIAVMSSR -DTVDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Roseibium sp. RKSG952 TaxID=2529384 RepID=UPI0012BB5170 --qHLQQTVTTWENRLDARIGVVLRDASSDWEI-SMRAKERFPMSSTFKSLLCGAVLARVD -AGQEDLSRRVTFSADDLVAYSPVTENHLQNGLTVGELCEATVALSDNTAGNLLLDTVGGP -EGLTAFLRYIGDQTTRLDRWETTLNEAVPGDPRDTSTPSAILTTLEALLLGDVLEPSSAA -QLRQWMIDDQVADALIRAHLPEGWVIGDKTGAGGNGSRAIIAFIEPKEDVHYFAAIYLTE -SDADFALRNQVVSEIGQAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429DDR4_9PSEU ---QFHDRLLELEKKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD -FLRDLLQRTVTGAGRIRAGLPPGWTVAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -AAKDAPYDEALLAEAARYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. RJGP41 TaxID=2108534 RepID=A0A2T0CI37_9BACI ---EATIKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHENERFAFTSTHKALAVGALLQQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGGALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAVIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI0006EB29F4 ---RATAAFEELERTYGARLGVYAVDTGDGREV-THHDDERFAYASTVKAFAAAAVLREHS ---PSGMDEVITYSRDDLVAHSPVTGKHVDTGMTLRELCDAAVRHSDNTAANLLFDALGGP -KGLAAALAEAGDTVTRVERREPELNQWAPGATRDTTTPRAWADDLRAFVLGDELGGRERA -QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR -GTEDAGYDDKLIEEAASVVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI000BACC096 ---ATIKKFEQLEKEYDAKLGVYAIDTGTKKTV-EFHGNERFAFTSTHKALAVGALLHQKS ---IEDLNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTKPERIEPDLNVVNPGETHDTSTPIALATSLQAFTLGDALPTEERE -LLIDWMKRNTTGDALIRAGVPKGWAVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -VEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI0005080E66 ---QFHDRLMELENKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD -FLRDLLQRTVTGAGRIRAGLPPGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -SAKDAPYDEALLAEAAKYVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000667D74D ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-1140 TaxID=1415549 RepID=A0A0N0TDR3_9ACTN ----VTARLRDLEREHTARLGVYARNMRTGRTV-VYRADERFPMASLFKTLAAAAVLRDLD -RDGEFLARRIHYTQADASQHSPVTKDHVATGMTVAELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSTGDRVTRLDRWEPALNSAEPWRVTDTTSPRAIGLTYARLVLGDALEPRDRS -RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPGDNPLVARTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=A0A066TXP4_9PSEU ------PDFAPLERGFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSAAAVLQRTS ---REGLAKVLTYRRADLQQNSPVTEKHVGTGIPLRDAIDAALRYSDNTAANLLFDQLGGP -PGLAAALRAIGDTTTHVDRTEPALNDFAPGDIRDTSTPRAMAGTLRAFALGDALPPEKRT -LYTDMMRANTTGATVIRAGTPAGWAVADKTGTGDYATRNDIAVVWPPGRAPIVLAIMSSR -RAEDAGHDDRLLAQAAKLTFDAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces chattanoogensis TaxID=66876 RepID=A0A0N0XSJ3_9ACTN ------GEFKKLERKFDARLGVYAVDTGTGREV-AYNDGERFAHASTFKALAAGAVLSKYA ---PSGMGKVIKYSKSDLVENSPITEKHVETGMTLRELCDAAVRFSDNTAGNLLFDALGGP -KGLDAALARIGDDTTRMERREPELNRWAPGEQRDTSTPRALAKDLRAFVLGNLLGKGERA -QLTKWLRTNTTGGELIRAGMPKDWKVGDKTGAGSYGTRNDIAVVWRPHAAPIVVAILSNR -SKAGAHYDNKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bohaiensis TaxID=1431344 RepID=UPI00143A3EE0 ---SAASTFEQLEEEFDARLGVYALDTGTGEEV-EYRSDERFAFASTFKAFAAGAVLAQYG ---LDGIDTVVSYEKADLVSHSPVTERFTTEGMTLRDLAAAAVRQSDNTATNLLFDALGGP -TGLQAALRGIGDETTNVNRTETELNEATPGDDRDTSTPRAMAETLNEYVFGDVLDAQESD -QLVEWMTTNTTGATLIPAGVPDSWTVGDKSGAGGYGTRNDIAVLWPEEGDPIIMAVLSSR -DEADATYDDALVARAATSA---- ->[subseq from] class A beta-lactamase n=1 Tax=Silvanigrella paludirubra TaxID=2499159 RepID=UPI001294F9BB -----QEKLLELEKSSDGRIGISAINTADNSKL-EYRAEERFAFCSTFKLMGVAAILKHSM -TNKNFLKEKINYKKDDIIAHSPITEKHLSDGMKIEELCKATITTSDNAAINLLIKKIGGL -NAVTSFARSIGDNNFRLDRYEIELNSAIPDDLQDTSTPSAMAKSIQKIVLGDVLALHQRE -LLQTWLKDSITGDAQIRSGVPKGWIVADKTGKGKYGTTNDIGVIWPPNCPPIVVAIYFTQ -KKQNAKYRDDVIASATNIIINAf ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus ottowii TaxID=2315729 RepID=A0A544WKV8_9BACL ------VVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQEKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDLRDTSTPNALANSFKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTEDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium leucaenae TaxID=29450 RepID=UPI00040994C9 ---DADKQLADLEKRTGGRLGVSVLDTETNISL-GYREAERFALCSTYKALAVGFVLARVD -QGVEKLDRRVTYGKDAVVTYSPETEKHAGTDMTIAQLCGAAITLSDNTAGNLLLDSFGGP -AALTAWLRTTGDTETRLDRKEPDVNQAIKDDPRDTTTPDSMLDTIGLLTLGNTLSETSRD -QLSNWLVNNTTGNARLRAGLPKEWKVGDKTGTGQNGSYADVAVISPTDRGPILVTTYVGE -ATAPAKDVEAVFAEVGKIIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. RV163 TaxID=1661388 RepID=UPI00064C11FF ------REFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEEDLVDYSPVTEQHVDTGMTLMEVADAAVRHSDNTAANLLFEELGGP -DAFEDELEEIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGSLREFTLGDALPEDRRE -VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVIWPPEGDPIVLAVMSSR -EAEDAEYDNALIARAAEVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=A0A1E7N7F3_KITAU -------AFKDLEQHFGARLGVYAVDTGSGREV-AYRSDERFAFASTIKSLLAGALLRTAS ---DQELDKVVTYRQDEVLTWAPITSRHVDTGMKVRDLAAAALEYSDNTAANLLMTELGGP -ENLQRTLRELGDPTTNVNRNEPTLNEATPGDPRDTSTPRAFAADLRRYVLGDVLTEDRRR -MLTDWMVGNTTGAPFIRAGVPAHWKIGDKTGNGGYGTRNDVAVAWPSGGSPVVLVVMSDR -GKADATSDDALIAEATKAVVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis trehalosi TaxID=109329 RepID=UPI000836B7F7 -----DAEFERLEEEYDARLGVYAYDTGSEETI-AFNADDRFAFNSTFKVLAVGALLQDRT ---LEDLEEVVHFTEEDLVNWSPITEQHVDTGMSLREVSDAAVRYSDNTAANLLFEELGGP -EGFEAALREIGDDVTNSDRIEPDLSSAVPGDDRDTSTPRAMATSLGEYTLGATLAADERE -FITDLLVRNTTGDALIRAGVPDDWKVGDKTGNGGYGSRNDIALLWPPEGDPILLAVMSSR -DQEDAEHDDALIADSAAVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5917 TaxID=1463873 RepID=UPI000563CAA3 ---KARRAFVRLERKFDARLGVYALDTGSRRSI-AHRADERFAYCSTCKAFLAGTVLKRNS ---LREMERRVRVRPQDLEGYSPIARKHVGSTMSLRELCDAAVRYSDNAAANLLFRELGGP -KGLQDALRDIGDRVTRADRYEVELSEGTPGDSRDTSTPRALVTDLRAFVLGDVLPGRKRE -VLTDWLKRNTTGDKLIRAGAPRGWEVGDKTGNGGYGTRNDIAVLWPPKGDPIPLAIMSRR -DTRDAEHDDALIAEAAEVAF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. W007 TaxID=1055352 RepID=H0BCD2_9ACTN -------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LRGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDGVTRMERRETELNEWTPGATRDTSTPRALAENLRAFVLGDTLAKPERA -RLAQWLTTNTTGGELIRAGVPKGWIVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. GC306 TaxID=2530367 RepID=A0A4R4SWZ0_9ACTN ---NVTEQISRLEKARDMRIGAYALDTGTGRAV-GHRADEAFPFASTFKAMACGAVLRKAR -NDPGLLDRVIRYKESDLSAHSPVTEKHVKTGMTVADLCHATITQSDNTAGNLVLKQIGGP -AGLTRFLRSLGDQVTRSDRWEPDLNDWRPGQKLDTTAPRPWAGDLRALTVGDALVPADRK -QLIGWLKATVTGDARIRAGLPHGWRAGNKTGTAGYGSANDIAIAWPPSGAPVIIAILTTK -RTPDAEPDEQAIARTTTILI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. AY3-1 TaxID=2217817 RepID=UPI0011ECA357 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKALAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRN -FLIDLMKRNTTEDNLIRAGVPAGWEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIADATKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus terrae TaxID=1914933 RepID=A0A429X2J3_9BACI ---NTDEKFAQLENEFDARIGVYAIDTGTNQTI-EYRPEERFAFASTYKALAAAILLQQNY ---LEDLMEVITYTEDDLVSYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLFEALGGP -KGFEQALRQMGDNVTQADRFEPDLNEFTLGETRDTSTPRALATSLQAFGVSDLLSDDKRE -LFTNWLKGNATGDTLIRASAPEGWEVGDKSGAGGYGTRNDVAIVWSPNREPIVIAILSKK -NTEDAEYDDALIAQAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia fusca TaxID=941183 RepID=UPI0007A73EC8 -----TQQFADLETAHGARLGVFALDTADGRSV-AYRDGERFPMASTFKGLACGALLHKHP -LSSGFFDRVIQYPRTDLVENSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLDGP -AGFTAFLRTLGDNTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDSLAEPERA -QLSAWLVASATGGNRIRAGLPAEWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK -SEQDAKPDNALVAAAARAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=alpha proteobacterium AAP38 TaxID=1523418 RepID=UPI0006B8E3A3 ----MREAMAALERARGGRLGVALLDTKTGAAM-NWRGDERFAMCSTFKFLLAGYILSRVD -AGQERLDRMVTFGKHELVTWSPLTEPHVDKGMSINDLCQAIMIQSDNTGANVLMRESGGP -TALTAFLRAAGDGVTRVDRIEPAMNVVGPDDVRDTTTPVSMLGLMRSLLLGEVLTPASRQ -RLTDWMIDNRTGKERLRAGLPAGWRIGDKTGTYD-AFNNDIAILWPPAGGPLLLTSYYAN -PTADKAVRNIVHAEVAAIVAKAy ->[subseq from] Beta-lactamase n=1 Tax=Lutibaculum baratangense AMV1 TaxID=631454 RepID=V4QXR4_9RHIZ ----VVEAAERLETELGGRIGVVLRE-QDGALVaTYRADERFPLGSTFKVLACGALLARVD -AGEDDLDRMIEYGREELVTYSPVTEKHAGQGMTLRDLCHATITLSDNTAGNLVLESIGGP -EGLTEFLRQAGDEVTRLDRWETELNEGRPGDPRDTTSPEAILATLERLLFGELLSPSSRR -QLEDWMIADQVADALIRSSLPDDWNIGDKTGAGGRGTRAIVAVIRPPESSPWLAAIYLTG -NEADLDTRNRVVAEIGAVMID-- ->[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus budapestensis TaxID=290110 RepID=A0A2D0J2X9_XENBU ---QIINQFIALEKSANGHLGVFLINTADNLTI-GYRANERFPLCSTSKFMVASALLKKSE -KDENLLNQRINYKQSDIVEYSPITEKHIASGMTLAELSAATLQYSDNTAMNLLLDQLDGP -RGLTKFARTIGDNKFRLDRKEPELNLVKPGDERDTSTPQAMAESLYKLTLGNVLATNQRV -QLAEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNKAPLVLVTYFTQ -PDKNAKARRDVLAEATRILIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000750A3E0 ---KMQLELMTLEKISGGRLGVAMINTADNSLT-LYRASERFAMCSTSKVMAVAALLKKSE -AKAEIMNERIVLQQSDLVTWSPVTEKNLSTGMTLAELSAATLQYSDNAAMNVILRYLGGP -SGATAFARSIGDSTFRQDRTEPELNTAIPGDERDTTTPLAMAESLEKLTMGNALAEPQRQ -QLVKWLQGNTTGDASIKAGLPAIWVVGDKTGSGDYGTTNDIAVIWPDSQPPLILVTYFTQ -PLKDAKGRKDVLAEAAKIVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rummeliibacillus stabekisii TaxID=241244 RepID=A0A143HHY9_9BACL ---HTEEAFKQLESEFDARLGVYAIDTKTKKSV-SYQSDERFAFASTYKALATGTMLKQQS ---IKDLDKIITYTKDDLVTYSPITEKHVDTGMSLKDIATAAIRYSDNTAGNLLFNEIGGP -RGFEKALRKMGDKVTKSNRLEPELNLTLPGDLRDTSTPRALATSLQKYVIGDVLTTKKKA -LLTDLLVGNATGDTLIRAGVPKDWVVGDKSGAGSYGTRNDIAVVWPPYRKPIVIAILSSR -NTKDATYDDALIAKAAKVVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BF87AE -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVMLDKYS ---LDGLDQRVTYTRKELVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=A0A1G6P237_9ACTN ---RATAAFEELERTYGARLGVYAVDTGDGREV-THHDDERFAYASTVKAFAAAAVLREHS ---PSGMDEVITYSRDDLVAHSPVTGKHVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP -KGLAAALAEAGDTVTRVERREPELNQWAPGATRDTTTPRAWADDLRTFVLGDELGGRERA -QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR -GTEDAGYDDKLIEEAASVVI--- ->[subseq from] Beta-lactamase n=1 Tax=Halopolyspora algeriensis TaxID=1500506 RepID=A0A368VJV5_9ACTN ---ALREEFDRLEREFGARLGVYAVDTATGQEL-AYHADERFAYASTLKALLAGAVLRQNT ---IGELNKKITYDRGALVPYSPITKKHVASGMTLRAVLDAAVRHSDNTAGNLLFREIGGP -QGLNAVLRSIGDTTTRVARIEPELNEFTPGDIRDTSTPRALATSLRAFTVGDALAADERA -LLNTMLRTTTTGDELIRAGAPAGWQVGDKSGAADYGTRNDIAILRPPEGAPIMLAILSDR -NTQDAEYDNALIAQAATVALRAf ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. LMG 12459 TaxID=1591131 RepID=UPI001262EAB2 ---TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGATLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAGTMRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis vastitatis TaxID=1905142 RepID=A0A229TGK2_9PSEU -------DFAPLERDFDARLGVYAVDIGTGREL-AHRADERFGYASTHKVFSAAAVLQRTS ---LEGLAKVLNYTRADLQPNSPVTEKHVTTGISLRDAIDAAVRYSDNTAANLLFRELGGP -AGLAAALRGIGDTTTHADRTEPGLNDLAPGDVRDTSTPRAMAVSLRAFTVGTALPPEKRT -VLTDMMRANKTGAALIRAGAPAGWTVGDKTGTGGYGTRNDIAVVWPPGRAPIVLVVLSDR -KTKDADHDDRLIAQAAKLALDSf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SCG1_KLEPN --------------QLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQA-------------------- ->[subseq from] Beta-lactamase n=2 Tax=Labrenzia alba TaxID=311410 RepID=A0A0M7AI34_9RHOB ----VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGDERFPMNSTFKAFLCAALLDAAS -NGTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP -EGVTAFLRGIGDDISRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDKTLAADARA -KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ -TTAAFEARNKAIASIAQAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD12A8 -----EAQLAALESKHPGRICVSILDLASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLVDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSMGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRLLFTDILTAASRS -QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ZL-24 TaxID=1933029 RepID=UPI000CD45BF5 ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGIRNDIAIVWPPGAAPIAIAVLSRR -DVKDAESDDALIAGAAKVALEAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces capillispiralis TaxID=68182 RepID=A0A561TGT2_9ACTN -------ALADLEREYGARLGVFAVDTGTGATV-VHRADERFAFCSTFKTLAAAAVLDRGP ---LDGLEQRVTYTRDDLVAYSPVAEKHVGTGMTLRQLGDAAVRHSDNAAANLLLRHLGGP -GALTAYLRGLGDRVSRLDHNEPELNRNPPGDPRDTTTPRAVTADYRALVLGDALPAAQRE -LLTDWLVRSTTGGERIRAGVPRGWKAGDKTGTGDWGRANDVAVLWPDRGAPIVLAVLTEL -PERAAAPSDPLVAEATRR----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces bingchenggensis (strain BCW-1) TaxID=749414 RepID=D7BS36_STRBB -----AREFRDLEHKFDARLGVYAIDTGTGREV-VYNDGERFAYNSTFKAMAAGAALKKFS ---LSGMDRKITYSKDVLVANSPVTEKHVDTGMTLGELCDAAVRYSDNAAANLILKELGGP -KALDATLEKLGDDVTRMDRPEPYLSEWVPGELRDTTTPRAFAKDLRAFVLGDVLAKGERA -QLTTWLRTNKTGDKVIRAGVPKGWVVGDKTGTGSYGGRNDIAVVWPPDKAPIVIAILSNR -HKKDAEPDDRLIAQAASVIA--- ->[subseq from] Beta-lactamase n=3 Tax=Burkholderiales TaxID=80840 RepID=A0A1F4G8M7_9BURK ---EWNETLANIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR -STAKPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. Root402 TaxID=1736527 RepID=UPI0006F4FB09 ---AWNEALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSMGDEVTRLDRTEPTLNEAGVGDPRDTTTPLAMLQTMQKLVLGNALSPTSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR -SMASPEQRDAAIAQVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 94 TaxID=2035218 RepID=A0A2G7ANM7_9ACTN ---------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGSTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. A7024 TaxID=1128680 RepID=UPI0013EBD8B9 ----ATREFKELERGYDARLGVYAVDTGTGREV-AYRDGERFAYASTFKALAAGAVLKKRQ ---LGGLDKKITYERDDLIANSPVTEKHVADGMTLGALCDAAVRYSDNTAANLLFDELGGP -AGLQKVLRAAGDDVTRMERNEPALSDWQPGQVRDTSTPRQLAQDLRAFTLGDELHKPERA -QLTDWLKRNTTGAELIRAGVPKQWKVGDKTGTASYGGRNDIAIIWRPNAAPLILAILTNR -KNENAEPDEKLIAEAAGAVADE- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. wa1063 TaxID=1828212 RepID=UPI000BEFF734 -------AFTALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNKWTPGATRDTSTPRALAGDLRAFVLGDALAKPERA -RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=A0A059W032_STRA9 -------ELHELERKYGARLGIYAVNTGDGREV-GFNADERFAYASTFKAFAAAAVLRKYS ---LSGMDKVITYSRSDLIDHSPVTEKHVGTGMTLRDLCDAAVRYSDNTAANLLFDVLGGP -QGLAAALAGTGDTTTKVERREPELNQWSPGATQDTTTPRAWAGDLRAYALGDALGKDERE -QFTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSSR -ATKDADYDNKLIAEAASVVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. RP6 TaxID=2489596 RepID=A0A3N6NTF3_9BRAD -----PAELEAYERDSGGRIGLHAENLATGRKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPTAMAGNLRRLVLGEALSAQSRL -QLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKPDAPILIAAYTQG -GTPNAAQIAALFARIGRMVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SolWspMP-5a-2 TaxID=1838281 RepID=A0A1C4SKJ7_9ACTN ------DRLRALEEEHDARLGVFAVNVRTGRSV-AHRADERFPVCSVFKTLAAAAVLRDLD -RDGEVLGRRIHYTEADLVGGSDRTREHLAEGMTIAELADVAIRYSDNTAGNLLLRELGGP -TAVTRFARSIGDRVTRLDRWETELNSGEPGRVTDTTSPRAIGRSYARLVLGDALTGRDRA -LLTHWLLGNTTSDERLRAGVPSSWTVADKTGAGDYGTNNDVGIAWTPDGTPVVLAILSTK -HVRDAAWDHPLVRKAASLLA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus simplex TaxID=1478 RepID=A0A098FLY9_9BACI ---ATIKKFEQLEKEYDAKLGVYAIDTGTKETV-EFHENERFAFTSTHKALAVGALLQQKS ---IEELNQRITYTSEDLVNYNPITEKHVDTGMTLKELSDASLRYSDNTAGNLILEQLGGP -AGFKKVLEGIGDNVTNPERIEPDLNVVNPSETHDTSTPIALATSLQAFTLGDALPTEKRE -LLIDWMKRNTTGDALIRAGVPKGWVVADKTGAGSYGTRNDIAIIWPSKGDPIVLAVLSSR -DEKEADYNDELIAEATEEVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora endophytica TaxID=1642495 RepID=UPI00101B850E ---DLDALFSELENEFDARLGVYAVDTGTESTV-AFREDERFAYASTHKVLSAAVVLDQNS ---IDDLEETVTYSSDELAAHSPITEQHVDTGMTLRELCDAALRFSDNTAANLLLEEVGGP -DGLERALEELGDDVTSVDRYEPELNEAAPGDIRDTSTPDALATDLLKYALGDVLPAEQQG -MLNDWLRGNTTGDTLIRAGVPAGWDVGDRSGAGGYGTRNNIAVIWPPDEEPIVMAVLSSK -DEEDAEHDDALIAEAAEIALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=UPI000751414C -----TARLRELEREHTARLGVYARNLRTGRTV-AYRAGERFPMASVFKTLTAAAVLRDLD -RDGEFLARRIRYTQDYVTKYSPVTQENLATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFCRSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA -RLTDWLLRNTTSTEKFRKGLPADWLLADKTGGGRHGGANDVGITWPPDGPPIVLSVLTTQ -PEEDAPADNTLVAETAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. sk226 TaxID=2034268 RepID=UPI000D1C578D -----TAAFEKLERAFDARLGVYAIDTGTGREV-IHNDRARFAYNSTFKALQAGVVLGEYS ---LDGLDRRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGGALPAAERE -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAVLSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI0009EF46D2 -----TATFAEMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTAADIVVNSPETEKHVDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP -EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRVLVVGTALPEPERD -QLAAWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK -PDQNAEPSNDLVAEATKAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=A0A059VQW6_STRA9 ---DFEGELQELERRYAARLGVYARNARTGQVV-AHRARERFAMCSTFKTVAAAAILRDHA --RCAPLDKVIHYPPADLLANSPRAAEHVDTGMAVGDLCAAAIQYSDNTAANLLLRQIGGP -AGLTRFFRSIGDRESRLDRWETELNDAVPGDLRDTTTPEALGTSYGRLTVGRALDPAARE -HLVTWLKGNTTSGERFRAGLPHDWVVGDKTGTGDYASANDVGVAWTTRQTPIVLAVLTSK -DAKDAPVDNALIADAARIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=A0A1I5KCS6_9PSEU -------DLAELERRYDARVGLYAINVRTGRTL-VNRPDERFALCSTFKTYAVAALLRDHG -LSSGYFDKVIRYTKDDLVSYSPETEKHVDTGMTVRALCEATMKLSDNTAANLLLRERGGP -QSIAPFARSIGDPTTRLDRWETELNTAIPGDERDTSTPAGLAAGYRALVLGDALAAPERD -QLTEWLLANTTGDECIRAGVPPTWRTGEKTGAGDYGTRNDAGVTWTEDGTPIVIAILTTR -PRQDDEYRNELLADTARAVAAH- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. PBL-H3 TaxID=434010 RepID=UPI00131FD54F ---TLQDGLRDIEATARGRLGVHIIDTATGREH-GWRADERFLMLSSFKLLASALVLARAD -RSEESLERRIRYRQQDLVPWSPVTEKHVGGELSLAQLCEATITTSDNTAANLILASYGGP -AALTAFARRLGDTVTRLDRTEPELNRAASGEPLDTTTPRAMAHTVHKLLLGDALAPASRE -RLLQWLLANTTGGTHLRAGVPAGWRVGEKTGTAGD-DANDIGIAFPPQRAPLIVTAYLAE -SATDAATREAALASVGRLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Allokutzneria sp. NRRL B-24872 TaxID=1137961 RepID=UPI000A3D0303 -----NDALLELEQKFGARLGVYAMATGTGKTL-AHRADERFAFCSTFKGLASAAVLHHNP ---ISHLDTVVKYTRDDVLKNATITPKHIATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP -AKLTEYLRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAIGTTYQKLVIGDALPQEKRA -FLRDLMERNTTGAQRIRAGVPRGWTIADKTGTGDYGTANDIGILWPPNSAPIVLALMSSK -PTKDAEYNQALLAEATSVVLA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces nigra TaxID=1827580 RepID=A0A2S1IC24_9ACTN ----VRARLRELERGHGARLGVYAHNVVTGRTL-THRADERFPVCSLFKPLAVAAVLRDLD -RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP -TAVTRFARSIGDRVTRLDRWETELNSAEPWRVTDTTSPRAIGGSYARLVLGEALDARDRA -RLTHWLLHNTTSVNRFRAALPPPWTVADKTGGGSYGANNDAGVVWTEEGVPLVLAVMTTR -PEQDAAYDHALIVEATRLVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A5B8Q0U6_BACME -----DREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDEVTLPERFEPDLNEVNPGETHDTSTARALAASLQTYVLGQALPEDKRE -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGSGSYATRNDIAILWPPKGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P1-18 TaxID=2024615 RepID=A0A5A7XXT0_9MYCO ------DALAALEARIPGRLGVYALDTATGATV-THRADERFLLCSTGKVLTVAAVLKRGE -SEPGLLDQVIRYDPSDVLEWAPVTSQHVAEGMTVSQLCDAAITVSDNTAANLLVRLLGGP -QAVTTYARTLGDGVTRVDRIEPDLNVAAPGDERDTSTPTQMATNLRTLVLGDALNDDSRR -RLTDLLKANTTGDKTIRTGVPRDWVVGDKTGSGAQRESNDVAVAWPPGRAPVLLAVYVAP -TDADADAMRRVIAEATRIAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. or20 TaxID=1828016 RepID=UPI000BF2385E -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLREYG ---LGGLARVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAEPERA -RLAEWLTTNTTGGELIRAGVPRGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TDADADYDNTLIAKATSAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000475E203 ---RAAKALAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST ---DDELNRVINYRASDLEDYAPITKRHMGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP -AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTQVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR -GSKDAASDDALIKDATKT----- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium nodulans (strain LMG 21967 / CNCM I-2342 / ORS 2060) TaxID=460265 RepID=B8IHY1_METNO -----IARLAALERQDGGRLGLTVRDTGTGRVL-SYRADERFPLCSTFKAVAAAAILARVD -RGEESLERRMTYGPEDLDTYAPVTGRRVAEGISLGDACAAAVIWSDNTAGNLMLQALGGP -EGVTAFARAQGDTVTRLDRTEPTLNTAIPGDPRDTTSPAAVTGLLERVLLGPALMADSRA -RLLGWMTESPTGTKRLRAGLPPGWTVADKTGTGENGTANVVALVRRPAGAPLLASVYLTQ -SPSAPEARNGLHAEVGRLIARTf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. AG236 TaxID=2184002 RepID=A0A369BRF2_9BACI ----SDREFAKLEDKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKRVDTGMTLRELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTPRALVSSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPKGDPIVLAILSNR -TEKDAEYNDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. SB0023/3 TaxID=2584084 RepID=A0A509EAV5_9RHIZ ----PQARLVALAHGFGGRLGVAIRDTGSGRSL-ALAADERFPLCSTFKVLAAAALLARVE -QGTETLARAMPYTAADLDSYAPVARRRLEAGMPLGEACAAALVWSDNTAANLVLQALGGP -EALTAWLRRIGDPVTRLDRWEPELNTAIPGDLRDTTTPAAMLATLERILLGPALAPESRA -RLAGWMMEARTGLKRLRAGIPPTWSVGDKTGSGANGTANVVAIVRPPGRAPLLAAVYITR -SDAPDAVRDAIHAEIGRLVV--- ->[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI000260492C ------DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ -QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP -EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH -QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVAHAPIVLAVYTSK -PDRNSKHSDAVIADASRIVLESf ->[subseq from] Beta-lactamase n=1 Tax=Marinitenerispora sediminis TaxID=1931232 RepID=A0A368T609_9ACTN -----EAAFAQLESEYDARLGVYAIDTGTEEVV-AYRPDDRFAYCSTHKAFSAAAVLDQNS ---FEELDEVVRYTEADLVPHSPVTEQHVDTGMPLIDLVDAAVLQSDNTAANLLFAELGGP -SGLQAALRETGDDVTHVDRVYPDLAEATPGDIRDTSTPQAMAATLRAYTLGDALRPEKRE -VLVDMLRRNPMSGELIRAGVPEGWVVGDKTGAGGYGTRNDIAVVWPPDDAPIVIAIMSSR -DAEDAQYDNALIAESAAVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=UPI0012B9DCD1 --qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTFGDTRFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNRLVLGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPIVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A097SR23_9BACT ---KLTKVVQAEEETLQARVGMAVFDTNTGETW-QYRGDERFPLNSTHKAFACAALLAKVD -GKSLTLDQPVSIRKEMLVPYSPITEKSLAPQMTFGEVCHAAVSYSDNTAANVVFDVIGGP -TGFTSYMRSIGDEKTRLDRKEPELNEATPGDVHDTTTPNAIVNSLRKILLGDVLSVSSRA -ELTQWMLTDQVAGALLRASLPSDWKIADKTGAGGNGSRSIVAVIWPPSKKPLVVGIYVTQ -TKASMQASNQAIAKIGTAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E2828D4 ---EYAERFAALEERYDARLGVFAVDTGTEETL-AHNADDRFAYASTHKAFSAAAVLRRST ---DEDLERVITYTEEDLQEHAPIAEENLDTGMTLLEVCDAAVRYSDNTAANLLFAELGGP -SGLQEELREVGDDVTHVDRIEPELSEGAPGDIRDTSTPRAMAATLRAYTLGDVLPQDRRE -ILVDMLRRNVTGDTVIRAGVPDDWTVGDKTGTAGYGGRNDIAVLWPPEGAPIVLAVMSSR -DTEGAERDDALIADAAAIVAE-- ->[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI0000678D84 ---MLRAQWAEIERGTGGRLGINLLDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANALFLLVGDS -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRK -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2D2CI72_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLISQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMSMAE-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00039A3450 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD -ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPNRAPIVLAVLSSR -DEPDASFDNALIAEAAEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003A8E3B3 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD -ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPNRAPIVLAVLSSR -DEPDASFDNALIAEAAEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sacchari TaxID=56458 RepID=UPI00123E25D7 ---TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGATLSVVELCRASMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00048F3866 ----TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT ---LPQMERLVRYGQEEIISHSPITAKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD25DEA --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAANLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Oceanobacillus picturae TaxID=171693 RepID=W9ADV7_9BACI ---KLDEQFAALEDDFDAQLGVYALDTGSNQTI-AYRAEERYAFSSTYKALAAAFVLKENT ---KEELNEIITYTVDDLVPYSPVTEKHVDTGMTLIEIGEAAVRTSDNTAGNLLFEALGGP -AKFEEALRQIGDEVTQADRYETELNEFNPEDTRDTSTPKALTTNLKKFAVGDLLTVEKRE -LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPPDREPIVIAIMSRH -DTEDADYDDALISEAAEVVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. SHU 166 TaxID=1591170 RepID=UPI0003A03FBB ---TLPQRLAEIERRSGGRLGVSLLD-GGGATLgGQRQNERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERYVGGTLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATMRALLLGDVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWQIGDKTGSNGTDTRNDIAIIWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Halopolyspora algeriensis TaxID=1500506 RepID=UPI000DF13500 ---ALREEFDRLEREFGARLGVYAVDTATGQEL-AYHADERFAYASTLKALLAGAVLRQNT ---IGELNKKITYDRGALVPYSPITKKHVASGMTLRAVLDAAVRHSDNTAGNLLFREIGGP -QGLNAVLRSIGDTTTRVARIEPELNEFTPGDIRDTSTPRALATSLRAFTVGDALAADERA -LLNTMLRTTTTGDELIRAGAPAGWQVGDKSGAADYGTRNDIAILRPPEGAPIMLAILSDR -NTQDAEYDNALIAQAATVALRAf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CC77 TaxID=1906739 RepID=A0A1S2KSY2_9ACTN ----TTGRLRELEREHGARLGVFAYDTGTHRMV-AYRQGERFPMCSLFKPLAAAAVLRDLD -RDGEFLARRIPYGVEDLEPWSPVTKDHVGAGLTVEELCDAAIRHSDNTAANLLLRELGGP -TAVTRFCRSAGDGVTRLDRWEPELNSAEPWRETDTTTPYAVARTYGRLVLGGLLEPRDRE -RLTGWLLGNTTSTERFRKGLPADWVLGDKTGGGSYGTNNDAGVTWPPGRPPIVLAVLTTK -PEPAALPDNPLVAGAARIVAD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SceaMP-e96 TaxID=1100824 RepID=A0A1C6NTA2_9ACTN ---RAAKDLAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRST ---DDELNRVINYRASDLEDYAPITKRHVGEGMTLRDLLKAAVQYSDNTAANLLLDQLGGP -AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPASGSPIVVAVLSDR -GSKDAASDDALIKDATKT----- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0003AAC764 ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BF9A31C ----SDREFAKLEEKYDANLGIYALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. NRRL B-16309 TaxID=1519494 RepID=A0A0M8XZU8_9ACTN ---AADADFARLEEDFDARLGVYALDTGSGEAV-GYRAEERFAFASTIKVALFGALLERAT ---PEELEKDVTITEDDLVNWNPVTEDNVGGDMSLLELGDAALRYSDNAATNLLLEELGGP -DALDAALEEIGDDVTSVDRIEPGLNEAVPGDERDTSTPRAMATTLEAFTLGDVLPEVDRE -ILTEMMRGNTTGDDLIRAGVPDGWEVGDRTGAGGYGTRNAIAVAWPPEDDPIVVVVMSSR -DQEDAEYDDALIAQATEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris TaxID=339 RepID=UPI0009C14241 ----LRARWAEIQRGTGGRLGISLLNSVTGWHI-GQRENERFPMCITFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFMRGIGDTKTRSDRHEPEMNRYAEGDPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAGRDAALKAVAAAVR--- ->[subseq from] Beta-lactamase n=1 Tax=Roseovarius sp. BRH_c41 TaxID=1629709 RepID=A0A0F2RN86_9RHOB ---RLAQTIAQIEQTLDARVGLHIHDSATGWSV-SHRPNERFLMASTFKAMLCGAVLSRVD -KGTLALDEQLEITDQDILEYAPITESEIGKTMSLGELCFAALDMSDNTATNLLIDRLGGP -HKVTAFLRAIGDPVSRLDRREPDLNTFTPGDPRDTTTPAAMASTLENILAGDALSPQSRA -QLVKWMSAGGVTGALIRASTPKGWQVADKSGSGAY-NRNIVAMVTPPDQPPYVITMFLSD -TDADFATRNAAVITLSKAVMD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces roseoverticillatus TaxID=66429 RepID=UPI0004C1B58D ----ISGRLRELEQEHSARLGVFAHNTVTGRTV-AHRADELFPMCSTFKTLAVAAVLRDLD -RKGEFLAKRIHYTKKEVEDYDKITDEHVAGGMTVEELCAAAVSYSDNGAANLLLRELGGP -DAVTRFCRSIGDGKTRLDRWEPALNSAEPDRITDTTTPRAIGRTYAHLVLGNALAPEDRK -RLTGWLLANTTSDQRIRKGIPAGWTVADKTGAGSYGTNNDVAVTWSPKGAPVVMSILTTK -HEATAKGDDALVAGTAKILA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509) TaxID=446468 RepID=D7AWL2_NOCDD ------REFERLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEEDLVDYSPVTEQHVDTGMTLMEVADAAVRYSDNTAANLLFEELGGP -DAFEDELEAIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGNLREFTLGDALPEDRRE -VLNDLLVNNTTGDALIRAGVPEDWRVGDKTGAGSHGTRNDIAVIWPPEGDPIVLAVMSSR -EAEDAEYDDALIARAAEIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium TaxID=374 RepID=UPI0004145EF7 -----PAELEAYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLLLGEALSAQSRL -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAAVWPKPDAPILIAAYTQG -GTPNAAQIATLFAQIGRMVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003A94D94 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD -ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEAAEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00112A076E -------ELETYERESGGRIGVYAENLATGKKL-TWRADERFVMCSTFKASLAACVLARVD -RGEEKLAATIAYGKADLLEYAPVAKQKLAAGMSVSDMCKALVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGEALTPASRA -LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPEAPILMAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00039B6277 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLREYAVDDALDPTDRD -ILNAWMRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEAAEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00035E3601 ----TDRAFAELERTFDARLGVYAVDTGDGRTV-THRPDERFAYASTCKALLAGAVLARKT ---LPQMERLVRYGREEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LITDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAVAVLSRR -DVKGAEADDALIAGAAEVALDAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=A0A0K8PLQ6_STRAJ -----TARLRELEREHTARLGVYARNLRTGRTV-AYRAGERFPMASVFKTLTAAAVLRDLD -RDGEFLARRIRYTQDYVTKYSPVTQENLATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAITRFCRSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGNALEPRDRA -RLTDWLLRNTTSTEKFRKGLPADWLLADKTGGGRHGGANDVGITWPPDGPPIVLSVLTTQ -PEEDAPADNTLVAETAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. rh34 TaxID=2034272 RepID=UPI000BF1D5A0 -----GRAFAALEKEYAARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRKHG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMVRRETELNEWAPDATRDTSTPRALAEDLRAFVLGDALAEPERA -RLRQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TEADADFDNTLIAKAASAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=UPI00140C5D4A -----ARQLAELERNAGGRIGVFAQEVDSGRSL-AYRADERFPMCSTFALLLAGAILQRSA -AQPDLLYRHVSYRREQLIDYSPIAEQHVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP -QEVTRFARSLGDGLSRLDRIEPELNRAEPDDPRDSTTPAAMTANLHALLFSPSLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLILSVYYWG -SPAMMDERNAVIAAVARVVAAEf ->[subseq from] Beta-lactamase n=2 Tax=Quasibacillus thermotolerans TaxID=1221996 RepID=A0A0F5HPF8_9BACI ---NTNERFIQLEKEFDAQIGVYAIDTGTDQTI-EYRPEERFAFASTYKALAAAILLKQNS ---LEELEKVITYTEDELVPYSPVTEKHVDTGMTLLELGEAAVRFSDNTAGNLLFEAVGGP -QGFEQALRQIGDDVTEADRLEPDLNKFTPGDTRDTSTPRALATSLQVFAVGGLLSGDKRE -LFTDWLKGNATGDPLIRAGAPEGWEVGDKSGAGSYGTRNDIAVVWPPNRKPIVMAVLSRH -HTEDAAYDDELIAQAAKITLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomonospora alba TaxID=183763 RepID=A0A0C2JN45_9ACTN -------DFKHLEKEYDATLGVYALDTGSGEAV-AYNADERFAYASTHKAFSAGAVLEQTP ---MDELDKHITYTEDDLLDYAPITEKHVEEGMELREVIDAAVRYSDNTAANLLFEELGGP -AGLQEALREIGDETTSVDRIEPGLNDWEPGDLRDTSTPQALATSLRAYTLGDVLPEEKRE -ILVDMMRRNTTGDDVIRAGVPGDWTVGDKTGSGAYGTRNDIAVLWPPQDDPIVVAVLTKR -DTSDAEREDALLAESAEVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Variibacter gotjawalensis TaxID=1333996 RepID=A0A0S3PS60_9BRAD ----FEDVMAEIEKSTGGRLGVGLLDLQTDKTA-FHRGDERFPMCSTFKFLLAAAVLAKAD -AREENLARRVRFEKAELLPHSPMTEQRAGDALTIAQLCEAAVTQSDNTAANLLLASLDGP -TGLTAFARKIGDTITRLDRTEPDLNDVAPGDERDTTSPRAMAEDMRKILVGDVLKIGSRE -QLSTWMRESATGKNRIRASLPMGWSAGDKTGTGPRGTSNDIAIMSPSGRQPIILTVYLTG -ATVDQTKQEAAIATVATAVIA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2233.5 TaxID=1938839 RepID=A0A2G6Z8H0_9ACTN -----HQTLRRLEREHQARVGAFAHNLTTGARV-AYRAHTRVPLCSVFKTLAVGAVLRDLD -HNGETLARRIHYTRADLVDNSPVTGAHLATGMTIAGLCAAALQRSDNTAANLLLRELGGP -AAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIAHTYTRLLVGDALTPADRG -RLTAWMKVNETNTDRFRAALPKDWALADKTGTGSYGTGNDVGVAWTPDGTPVVLAVLTGK -PEQAAACDDALIADVTKVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 14C53 TaxID=2508997 RepID=A0A5C4J4G1_9ACTN ---EVTAKLRRLEQARGTRIGAYAVDTGTGRFV-AHRADEAFPFASTFKAVACGAVLRKAR -NDPGLMDRVIRYKKSDLAAFSPVTEKHVGTGMTVAGLCHATITHSDNTAGNLVLKEIGGP -AGLTAFVRSLGDTVTRSDRVEPGLNDWRPGEKRDTTAPRAWAGSLRALTAGDALAPADRD -RLNAWMKATVTGGRRIRAGLPEGWAAGDKTGTGGYGSANDIAIVWPPSRAPLVIAILTTR -PDAGAAADERAIAETARVLAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI000491CDF5 ---DLDHEFRQLEKRFDARLGIYAIDTGTGRTV-RYQANERFAYASTFKALAAAEVLDETT ---DAELEQVVRYSTDDLVDYSPITEQHVVEGMTLRAIAEAAVRYSDNTAGNLLLDHLGGP -ERFEKELKGIGDTVTDAARYETDLNEATPGDPRDTSTARALTEDLREYAVDDALEPGDRD -TLNGWLRGNTTGGELIRAGVPDGWVVGDKSGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5Q2F5L8_9BACT ------------EDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMGDNTAANLLLTTIGGP -KWLTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFITDKSGAGERGSRGIIAALGPDGEPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces autolyticus TaxID=75293 RepID=A0A1P8XPP4_9ACTN ---AFTGEFKKLERAHDARLGVYAIDTGTGHEV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIKYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDELGGP -GGLDAILEKMGDDVIQMEHYEPELSRWVPGATADTSTPRAMAEDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGVPKGWVVGDKTGSGSYGARNDIAVVWPPDAAPIVMSLMSYR -GDKDADYDEKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia brevicatena TaxID=37327 RepID=UPI000687C109 -----NRTFTDLEAEHGARLGLFAIDTADGHSV-AYRDGERFPMASTFKGLACGALLHEHP -LSSGFFDRTIHYPRTDLVENSPVTEKHADTGMTVAALCDAAITVSDNTAGNQILKLLGGP -AGFTAFLRTLGDNISRLDRWETELNTAIPGDERDTTTPAALAADYRTLVVGDSLAEPERA -QLTSWLVASTTGGNRIRAGLPADWTVGNKTGSPAYGSALDVAIAWPPGRAPVVITVLTTK -SEQDAEPDNALVAAAARAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus subtilis TaxID=1423 RepID=A0A0D1IPB2_BACIU -----NKKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNEQFAYASTYKVLAAAAVLKKNS ---IEKLNEVIHYSKDDLVTYSPITEKHLDTGMSLKEISEAAIRYSDNTAGNILLQQLGVP -KGFEKSLKQIGDHVTKAKRFETDLNSAIPGDIRDTSTAKALATDLKAFTLDNTLTTDKRT -ILTDWMRGNATGDELIRAGAPIGWEVGDKSGAGSYGRRNDIAIVWPPNRAPIVLAILSNR -FTKDANYDNALIAEAAKVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. C TaxID=253839 RepID=D9VLA5_9ACTN ---RVARALAELEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD -HDGSVLARRIHYTQADIARYSEWTKRHLANGLTIGELCEVSITYSDNTAANLLLRELGGP -AAVTRFARSLGDPVTRLDRWEPELNSAEPERVTDVTTPRAIARTYARLVLGDALGRADRG -LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIAWRPHGAPLVLAVLTTK -PAQDAKADDTLVSRTARALAGAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0006DA5099 -------AFAALEKEYAARLGVYAVDTGTGLTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALAEPERA -RLAQWLTANTTGGELIRAGVPKGWAVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKATSAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas cucurbitae TaxID=56453 RepID=UPI00132E9987 ----LRAQWADIERGTGGRLGISLLHSATGWRL-GQRENERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQPVKIRASDMLEHAPVTKGHVGGALSVGDLCRATMIYSDNPAANRLFPLVGGP -PGVTAFLRGIGDAKTRSDRYEPEMNGFAPGEPRDTTTPVAMASTLRTLLLGAALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAVREW- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI000688AF9C ------DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ -QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP -EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH -QLMSWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVGHAPIVLAVYTSK -PDKESKHSDAVIADASRIVLESf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=A0A1D3N9I2_BACMY ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEVTYDNQLIADAAEVVIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. (strain ORS 375) TaxID=566679 RepID=H0SRU7_BRAS3 ---DLQATLAGIETDSGGRLGVALLDTASGALS-GHRLDERFPMCSTFKALLAAAILTKVD -AGAEQLSRRLPIAPSDILSYAPVTKLHVGSSLSVCELCEATVTLSDNTAANLLLATLDGP -AGLTRAIRGFGDAITRLDRIEPALNESVPGDPRDTTTPTAMAQTLAKLTTGDTLSAASRD -ILNGWLIGCKTGAAKLRAGLPGSWRVGDKTGAGDNGSSNDVAVIWPAGRAPVIVTSYLTE -TKAGDDRRNAAHAAVGRAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia suaedae TaxID=735517 RepID=A0A1M7P9E4_9RHOB ----IDTVIARREEELGARIGVQVREREGGFNY-AHAADDRFPMASTFKALLCGAVLARVD -AGEEDLSRRITYKAADLVAYSPATEKHVKDGMTIGKLCEAAVTLSDNTAANLLLESVGGP -QGLTAFLRWSGDSTTRLDRTEPDLNEALPGDPRDTTTPAAMSETIDRLVFGDVLMTRSRA -QLRQWMIEDKVADALIRSKLPKGWTIGDKTGAGARGTRGITAFLIAPDGRTFLATIYLTE -NEADLKQRNQVIADISEAIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia TaxID=1817 RepID=UPI0009FBC6F7 -----TATFADMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP -EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERD -QLATWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK -PDQNAEPSNDLVAEATKTAVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces kanasensis TaxID=936756 RepID=A0A100YAJ1_9ACTN -----RGQLRALERRHDARLGAFAHDTGTGRTV-LYRADERFPMASLFKTLAAAAVLRDLD -RDGEVLARRVHFTAAYVEQYSPVTRENVATGMTVAELSAAAICQSDNTAGNLLLRELGGP -TAITRFCRSLGDDTTRLDRWEPELNSAEPWRVTDTTTPRAIGRTYGRLVLGSALAPDDRE -RLTAWMLANTTSEERFRKGLPADWVLADKTGGGEYGGNNNVGVAWPPGRPPVVLAVLTTR -FAPDATADDALVAEAARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000649C59E ----SDREFAKLEEKYDANLGVFALDTGTNKTV-TYHPDERFAYTSTHKALAVGALLQQKS ---IEDLNERIFYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNTAGNLILQQLGGP -DGFKEALENIGDDVTLPERFEPDLNEVNPGETHDTSTARALASSLQTYVLGQALPEDKRA -LLTDWMKRNTTGDALIRAGVPKSWEVADKTGAGSYATRNDIAILWPPNGDPIVLAILSDR -TEKDAEYHDKLIAEAAKQAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharomonospora glauca K62 TaxID=928724 RepID=I1D1I3_9PSEU ---SVSAELRALESRHAARLGVFALNVRSGAVV-SYRAHELFPMCSTFKTLEVAAVLRDLD -HDGTYLDRWVHYTEADLVPGSPITEQHAVTGMRVEDLCAAAIRQSDNTAANLLLRPLGGP -SGITRFCRSLGDSVTRLDRYEPDLSDGVPGDRRDTTTPAAIAADYRRLLLGRALDDADRD -RLVTWLTESVTSDTRFRAGLPSHWRVADKTGSGGYGTANDVGVAWTDDGTPLVLAVLTTK -EVEDADWDDDLVAGTAELLA--- ->[subseq from] Beta-lactamase n=2 Tax=Roseovarius sp. A-2 TaxID=1570360 RepID=A0A1V1UC03_9RHOB --dALQQMAQEVEARIGGRIGYAMADLASGQSW-GHRANERFPMSSTFKALLCGVILMRVD -AGEERLDRRIAFGRDDLVTYSPVTEARIDKGMTVGDLCEAAITISDNAAGNLLLATVGGP -EGFTAALRGLGDRTTRLDRWETTLNEGRPGDVRDTTTPHAALATLRTLLFGDSLSPASRR -QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPSPDRPVLTAIYMTQ -NDADMSARNAAIAKIGAAMFK-- ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Xenorhabdus bovienii str. oregonense TaxID=1398202 RepID=A0A077NR36_XENBV --nQITNQLSALEKNANGRLGVVLIDTADHSTI-TYHAHERFPLCSTSKMMAVSALLKKSE -TDEGLLNQRIHYQQSDIVEYSPITEKHLQDSMTLAELSAATIQYSDNTAMNLLIDQLGGT -HDVTRFARSIGDNAFRLDRKEPELNMVTPVDERDTTTPQAMADSLYKLALGNTLAATQRT -QLVEWLKGNTTGGASIRAGVPDNWIVGDKTGRCDYGSTNDIAVIWPDDKAPLILVTYFTQ -PNKDAKAHPDVLAAAARIMTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces swartbergensis TaxID=487165 RepID=A0A243S9R9_9ACTN -----TARLRELEREHTARLGVYARNLRTGRTV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRIRYTQDYVTRYSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP -TAITRFARSIGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPRDRA -RLTDWLLRNTTSTEKFRKGLPAEWLLADKTGQPEYGGAHDVGITWPPDGTPIVLSVLTTQ -PERDAPADNALVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ865 TaxID=1288081 RepID=UPI0003FC9E5E ------RELAALEREYDARLGVYAVDTGSGREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ARELDEVVTYSADDLIAHSPVTGEHVGTGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEALGDDVTRMVRDEPELSRWHPDDTRDTSTPRALAGDLRALVLDDALGKRDRA -RLTEWLRTNTTGDTLIRAGVPGTWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAIMSNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5QBE2_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSENHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAILRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASM------------------ ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. Root136 TaxID=1736458 RepID=A0A0Q7NWR6_9NOCA -----TATFADMETKYGARLGLSVVDTGSGATV-DYREGERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITQSDNTAGNMLLRLLGGP -EGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERD -QLATWLKASKTGAKRIKAGLPTDWIVGDKTGSPAYGSALDVAIAWPPNRAPLVLAVLTTK -PDQNAEPSNDLVAEATKTAVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2DY68_STRVZ ------AGLRALEREYGARLGVYARDTATGRTV-AHRADEQFPMCSVFKTLAAAAVLRDLD -HDGAHLAQRVHYTLQDVTDGGSVTERNIASGLTVAELCSAAIAQSDNAAANLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIGRTYARLTLGDALDAGDRE -QLKRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLAILSTM -PEATTPRDDTLIARTAKLLAD-- ->[subseq from] class A beta-lactamase Bla1 n=1 Tax=Bacillus mycoides TaxID=1405 RepID=UPI000B442AB4 ---ATYKEFSQLEKKFDARLGVYAIDTGTNRTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IEKLNEVITYTKDDLVEYSPVTEKHVDTGMALGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRVTMADRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAHKRN -ILTEWMKGNATGDKLIRAGVPTDWEVGDKSGAGSYGTRNDIAIVWPPNRAPIIIVILSSK -DEKEVTYDNQLIADAAEVVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0002F21C07 --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALHLAE -QKKLNLNATTKVKESDLVTWSPITEKLTGQEITVQKACEATMLMSDNTAANIVLHQIGGP -EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSTMVELLNTLLLQDGLSQESQQ -QLLTWMRNNKVSDPLIRSVFPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ -TQLDMAQRNRVINRVANLVFQQf ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=A0A5E8KPV6_9XANT ---MLRAQWAEIECGTGGRLGINLFDSATGWRL-GQREDERFPMCSTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLFGDP -AGLTGFLRGIGDAQTRSDRYEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPSSRT -QLTDWMIDNRTGDDCLRAGLTREWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. C TaxID=253839 RepID=UPI0001B5361B ---RVARALAELEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD -HDGSVLARRIHYTQADIARYSEWTKRHLANGLTIGELCEVSITYSDNTAANLLLRELGGP -AAVTRFARSLGDPVTRLDRWEPELNSAEPERVTDVTTPRAIARTYARLVLGDALGRADRG -LLTGWLCANTTSGARFREGLPAEWRLGDKTGGGSYGTNNDVGIAWRPHGAPLVLAVLTTK -PAQDAKADDTLVSRTARALAGAf ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia sp. AG348 TaxID=2183906 RepID=A0A369A8C5_9ENTR -------AVARLEEHLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP -AAVTRFFADSGDSVTRLDRGEPELNSAVPGDLRDTTTPLAVSHTLQKLALGELLTPRSRA -QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD -TNATMAQSNDAIARIGKAIFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. RTd22 TaxID=1841249 RepID=UPI0007C44C2A ------GELKALEREYDARLGLYAIDTGTGRQV-AYRDGERFGFHSTFKALAAGAVLRKYS ---LSGMNKLITYSRDDLVDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDAIGGP -KALEREVRRVGDDVTRMERIEPELSKWVPGDTRDTTTPRALAKDLRAFALGDVLRKPERA -QLATWLKTNTTGDALIRAGVPGGWVVGDKTGSGFYGARNDIAVVWRPDAAPIVMAVLTNR -GEKDDVHDDKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A4V3FZK0_9NOCA --------LVELEGRYDARLGVYASSSNTGRVV-EYRADERFAFCSTFKTLAVAAVLGKYP ---LSYLDTVVHYTAADLQSYAPIAEQKLDTGMTVGELCSAAVQYSDNTAANLLLQMLGGP -SAVNAYLRSIGDDVTRLDRIEPELNTAIPGDDRDTTSPRAIGTDYERLVLGDALTPDKRE -VLADWLRGNTTGAEQIRAGVPQGWTVADKTGSGDYGTSNDVGVAWTDTSDAVTISILTTR -SDRDDAADKAIIADATRLVVS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. So13.3 TaxID=2136173 RepID=A0A5R9M9F1_9ACTN -------DFQRLERTYDARLGIYAVNTGNGREV-AYRDTERFAYASTFKAFAAAAVLRKYS ---LNGMGKVVKYSRADLLSNSPVTAKHVETGMTLRELCDAAVRYSDNTAANLLFAALGGP -KGLAAALAEAGDTATRVERREPELNEWTPGATRDTTTPRAWAANLRAFVLGDALGKDERA -QLAQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPNAAPIVMAIMTNR -GTADAPYDNKLIAEAASVVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albulus TaxID=68570 RepID=UPI00056F17B9 -------ELHELERKYGARLGIYAVNTGDGREV-GFNADERFAYASTFKAFAAAAVLRKYS ---LSGMDKVITYSRSDLIDHSPVTEKHVGTGMTLRDLCDAAVRYSDNTAANLLFDVLGGP -QGLAAALAGTGDTTTKVERREPELNQWSPGATQDTTTPRAWAGDLRAYALGDALGKDERE -QFTQWLRTNTTGDELIRAGVPKGWDVGDKTGGGGYAVRNDIAVVWPPGAAPIVMAIMSSR -ATKDADYDNKLIAEAASVVTK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus cereus TaxID=1396 RepID=R8DTE4_BACCE ---AIHDAFSQLEKKFDARLGVFAIDTGTNQTI-TYNADKRFAYASTHKALAVGALLQKKS ---LRDLDQVIPYTQDDLVNYNPITKDHVNTGMTLKDLCDASIRYSDNTANNLILKQIGGP -KGMEQALRGIGDTVTNSERFEPELNVLEKGEIQDTSTPRAIATSLQAFTLGNALPKEKRT -ILINFLKGNTVGDTLIRAGVPKGWEVADKTGAGSYGTRNDIAVIWPPNGKPIVLAIMSDR -NTKDATYNDKLIAQATKEIMD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cellulosae TaxID=1968 RepID=UPI0004C9A449 ------GAFRQLEREFDARLGVYALDTGTGRSV-AYQADERFAYASTFKALAVGALLQRRG ---SAGLDKVITYSQDDLVEYSPVSENFVETGMSLRELCAATLWYSDNTAANLLLEELGGP -DGLEKALERLGDDVTEMDRYEPDLSDGTPGDLRDTSTPRAIAGDLRAFLLGKALDRDERA -LLRTWMETNTTGETLIRAGLPDDWTVADKSGSAGYGGRNDVAVVWPDDGDPVVLAVMSSR -DTQGAERRDALIAKAATVAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Gha TaxID=1855318 RepID=A0A1I3P3B3_9BRAD -------DLESYERESGGRIGVHAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEKLAATISYGKADLLEYAPVAKQNLSTGMSVADMCKASVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSPPGDVRDTTTPAAMAGNLKRLVTGEALSAASRA -QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPDAPILITAYTQG -GTPDAAQLEAVFARIGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=A0A4E0Q2S2_9BRAD ------SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD -RGEEQLAAMIRYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVTGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPSVAQIASAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093B6A66 ---QFHDRLMELENKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD -FLRDLLQRTVTGAGRIRAGLPSGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAIMSSK -SAKDAPYDEALLAEAAKYVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Franconibacter pulveris TaxID=435910 RepID=UPI00056D6793 ---QLTAAAQQEEKTLNARLGVTVLDTATGKTA-SYRGDERFPLNSTHKALLCGALLKQAD -EKKVSLTEAVRFDKSRLVEYSPVTEKHTAPQMNWLQLCSAAVSYSDNTAANLISQKAGGP -QGVNAFLRANGDKTTRLDRLEPALNEARPGDERDTTTPQAISRTLQTLLLGDALSEASRK -QLIRWMMDDKVADALLRKSLPKSWTIADKTGAGGYGSRSIISMVWPEKGAPLVVAIYITQ -TDASLSQSNAAIARLGRVIFQQ- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Enterobacterales TaxID=91347 RepID=BLAN_SERMA ---AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA -IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGIGTANDYAVIWPKNRAPLIVSIYTTR -KSKDDKHSDKTIAEASRIAIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI0013630057 -------AVARLEEHLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP -AAVTRFFADSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLALGELLTPRSRA -QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD -TKATMAQSNDAIARIGKAIFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. b84 TaxID=1827631 RepID=UPI000BF20138 -------AFTALEKEYTARLGVYAVDTGTGRTV-AHRDGERFAYASTFKALAAGAVLRAYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAKPERA -RLAQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKATSAAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium haemolyticum TaxID=394935 RepID=A0A1W0DC29_9NEIS ----TARQLAELERNAGGRIGVFAQEVDSGRTL-AYRADERFPMCSTFALLLAGAILQRSA -AQPDLLYRHVSYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFSDNTAANLLLEQLGGP -QEVTRFARSLGDGLSRLDRIEPELNRAEPDDPRDSTTPAAMTANLHALLFSPSLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANDVAVAWRPGKSPLILSVYYWG -SPAMMDERNAVIAAVARVVAAEf ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D9WC41_9ACTN ------GELKALEREYDARLGLYAIDTGTGRQV-AYRDGERFGFHSTFKALAAGAVLRKYS ---LSGMNKLITYSRDDLVDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDAIGGP -KALEREVRRVGDDVTRMERIEPELSKWVPGDTRDTTTPRALAKDLRAFALGDVLRKPERA -QLATWLKTNTTGDALIRAGVPGGWVVGDKTGSGFYGARNDIAVVWRPDAAPIVMAVLTNR -GEKDDVHDDKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=UPI00084C8C36 ----LKRAFAGLERKFDARLGVYAIDTGSGRSI-THRPDERFAFASTCKALLAAVMLEKNS ---LRQLDRLVRYDRDDLAGYSPITEKHLDTGLTLRELCDATVRYSDNGAANLLFHEIGGP -KRLEAALVSIGDRVTRCDRYEDALSEALPGDLRDTSTPRALATDLRTYVLGDRLPADKRD -VLTDWLKRNTTGDKVIRAGAPAGWVVGDKTGTGGYGTRNDIAIVWPPKAAPIAIAVMSRR -DEKDAEPDDALLAGAAKVTLDAf ->[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora erythraea TaxID=414996 RepID=A0A099D5U0_9ACTN ------ADFRRLEREFDARLGVYAVDTATGREL-SYRADERFAYASTHKALTAGAVLRRTS ---IEGLDKPITYDQADLVTYSPITKKHVDSGMSLRSVLDAAVRYSDNTAANLMFDEVGGP -DGLSAALREIGDTTTHVDRIEPELNATEPGDIRDTSTPRALATSLRAFSVGNALPKDERA -LLNRMLRNVTTGDELIRAGAPDGWRVGDKSGAAEYGTRNDIAVLWPPEGAPVVLAVLSDR -ASQDAEYDNALVARAAKTALREf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces uncialis TaxID=1048205 RepID=A0A1Q4V715_9ACTN ----FADELKALERKFDARLGVHAVDTGSGREI-AHNDRERFPYASTFKALAAGAVLREQS ---PSGMNRVVKYSEDDLIPHSPVTEKHVRTGMSLSALCDAAVRHSDNAAANLLFDELDGP -EGLDEVLEEVGDDVTRMVRREPELNRWAPGETRDTSTPRALAGSLRAFVLGDALGKDDRA -TLTKWLRTNTTGDALIRAGVPEGWTVGDKTGTGSYATRNDIAVVWPPGGTPIVMAIMSSR -DEKDAVHDDKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Belnapia rosea TaxID=938405 RepID=UPI000B84FF77 ----ATDALAALESRQGGRLGVAILDTGTGRAL-AHRGEERFPLCSTFKFLAAGLVLARVD -RGEEWLDRRVAYGRGALVPYSPVTGPGAEAGMTMGAICDAAVTLSDNTAGNLMLDSFGGP -AGLTAWMRGLGDPVTRMDRREPELNLVPPGDERDTTTPLAMIGLMRALLLGDALRPASRE -QLAAWLVACRTGDRRLRAGLPTGWRVGDKTGTGPDIPTNDIAVAWPPGRAPILIAAYLLG -ARGSEAERSAVLAEVGRIAAQ-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00037432C4 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -SAISNEQRAQVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 4R-3d TaxID=2559605 RepID=A0A4Y8Y4A6_9ACTN ----LKRAFAGLERKFDARLGVYAIDTGSGRSI-THRPDERFAFASTCKALLAAVMLEKNS ---LRQLDRLVRYDRDDLAGYSPITEKHLDTGLTLRELCDATVRYSDNGAANLLFHEIGGP -KRLEAALVSIGDRVTRCDRYEDALSEALPGDLRDTSTPRALATDLRTYVLGDRLPADKRD -VLTDWLKRNTTGDKVIRAGAPAGWVVGDKTGTGGYGTRNDIAIVWPPKAAPIAIAVMSRR -DEKDAEPDDALLAGAAKVTLDAf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium genosp. SA-3 TaxID=508868 RepID=A0A4Q7F9D5_9BRAD -------ELEAYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAIIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTTFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSPTSRA -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPRPDTPILIAAYTQG -GTPSAAQIAAAFARIGRMA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia xishanensis TaxID=238964 RepID=UPI000A05F6EE ----ATTSFTEMEAKHSARLGVYAIDTGSGRTV-AHRDGERFPIASTFKGLACGALLRDHP -LSTGYFDQVIHYSRSEIVVNSPVTEQRVDTGMTVAELCEAAITVSDNAAGNQLLKLLGGP -EGFTAFLRSIGDTTSRLDRWEPELNTAVPGDERDTTTAAALATDYRNLVLGDVLAEPERA -QLKSWLIASRTGADRIRAALPADWTVGNKTGSPAYGSALDVAVVWPPGRSPLVIAVLSTK -FEQNAKADNPLVAEATRAAVGMf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNZ288 TaxID=2512147 RepID=A0A4Q8BNL3_9ACTN ------RELAALEREYDARLGVYAVDTGSEREV-AYRAGERFPYASTFKALAAGVVLRTHS ---ARELDKVVTYSADDLIAHSPVTGEHVATGMTLRDLCEAAVRYSDNAAANLVLAELGGP -AGMDAELEALGDDVTRMVRDEPELSRWNPDDTRDTSTPRALAEDLRALVLDDALDKRDRA -RLTEWLRTNTTGDTLIRAGVPETWRVGDKTGTGSYGARNDIAVLWPPDRAPIVLAVMTNR -TQRDAEPDDALLADAASAVA--- ->[subseq from] Beta-lactamase n=2 Tax=Aureimonas sp. AU4 TaxID=1638163 RepID=A0A0P0ZA15_9RHIZ ---RLEDVIGREEKAIGARLGVAIHDTHEDVWW-RHRSDERFPMCSTFKVLAGAATLKRVE -RREDDLTRRVSIAPGDVVTYSPVTEKRVGENMILAEVLQAALTMSDNTAANILIDRLGGP -EAVTRFARSIGDGTTRLDRRETDLNEATPGDPRDTTTPEAMTRTLEKLIVGDALQPTTRL -MLEGWMVANTTGDAKLRAGLPPSWRVGDRTGGGAHGTMGDIAVIWPIDRKPVVASVYITE -TDASVDRRNETIAAIGKALAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TaxID=1931 RepID=A0A353K576_STRSQ ----TAGAFEELEDEYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYG ---EGGTDRLITYSEDDLVPDSPVTEKHVDAGMTLDALCDAAVRYSDNTAANLLLGQLGGP -KALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA -RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGSGGYGVRNDIAVLWPPDRAPVVVAVMTNR -GREGDTHDNRLLAEAASVVT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sparsogenes DSM 40356 TaxID=1331668 RepID=A0A1R1SM23_9ACTN -------DFKKLEREFGARLGVYAIDTGTGREV-AYNDGERFAYNSTFKALACGVLLDKVS ---LGGMDKKITYDRSVLLPNSPVTEKHVDTGMTLAELCDATIRYSDNAAANLILKELGGP -KALDAALEEMGDDVTRMDRPEPYLSRWVPGETRDTTTPRAFAKDLRAFVLGDALGKAERA -RLTTWLRTNKTGDTVIRAGVPKGWVVGDKTGTGSYGARNDIAVVWPPHKAPIVMAILSHR -TAKDAEPDDRLIAKAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229SB19_9PSEU ---QYHDRLLELEKKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRDDLMKHAPVTGQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -AELTAFTRGLGDTVTRMDRIEPLITEATPGDPRDTTSPRAFGTDYERILLGDTLAGDKRD -FLRDLLQRNATGADRIRAGLPSGWTIADKTGTGDYGTLNDIAVVWPPGKPPIVMAVMSSK -AAKDAPYDQALLAEAAKYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sacchari TaxID=56458 RepID=A0A0A8DSR6_9XANT ---TLQLRLAEIERRSGGRLGVSLLD-GGGATLgGQRQDERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGATLSVVELCRAAMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPRDTTTPAAMAATTRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas cannabis TaxID=1885674 RepID=UPI000573BF00 ---MLRAQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -QGKLTLTQPVKIRAADMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAANLLFPLVGDP -AGLTAFLRSIGDTKTRSDRYEPEMNGFAPGELRDTNTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLATYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID486 TaxID=2690264 RepID=UPI00136BE945 --------LAELEQRYGARLGVYARNVRTGRTL-AHRAGERFAMCSTFKAFAAAAVLRDRA --GCAPLNRVVHYPPLDLLPNSPRTTEHQATGMTVADLCAAAIQYSDNAAGNLLLREIGGP -AGLTRFYRSLGDRTSRLDRWEPELNTAIPGDPRDTTTPEAVAASLEHVTLGRALAPAGRE -RLVGWLKGNTTSAARFRAGLPGEWTVADKTGTGSYATANDIGVAWTTRGTPVVLVVLSAR -PTPDAAVDEKLVEEAARVMA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0261 TaxID=1703931 RepID=A0A1Q5EIG3_9ACTN -------AFAALEKEYAARLGVYAVDTGTGRTV-AHRDRERFAYASTFKALAAGAVLRGYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGDLCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMERRETELNEWTPGATRDTSTPRALAGDLRAFVLGDALAGPERA -RLAQWLTANTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -RDADADYDNTLIAKAASAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BB15780 ---DTRARLRELEARHGARIGAFAYNLRTEATV-RHRAAERFPGCSVFKTLAAAAVLRDLD -QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PARDAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia aobensis TaxID=257277 RepID=UPI0002F7E552 ------TEFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP ---PAELDRRVTYTRADLVPNSPVTEQHVDQGMTVREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAVGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLLHYVLDPSVAADDRD -VLTGLLRANTTGAALIRAGVPAGWQVGDKTGGGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A3S9Y3R9_9ACTN ----FAREFKELERKYDARLGVYAVDTGTGRRV-AYKDGERFSYNSTFKALAAGAVLRKHS ---PSAMDRVIKYSRDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP -KRLEAVLKGIGDDVTRMERIEPQLSRWTPGDTRDTTTPRTLAKDLRAFVLGDVLDKGDRK -QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGSYGARDDIAVVWPPGRSPIVVAIMSNR -FKKDADFDNKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. JHA19 TaxID=1577588 RepID=UPI0006E2BC83 ---DVRARLRELERGHGARLGVYAHNVVTGRTV-THRADERFPVCSLFKPLAVAAVLRDLD -RDGEVLARRIHYTEADLVANSDVTRAHLETGMTVAELADAAIRFSDNTAGNLLLRQIGGP -TAVTRFARSIGDGVTRLDRWETELNSAEPWRVTDTTSPRAIGGSYARLVLGDALDARDRA -RLTHWLLHNTTSVNRFRAALPPPWTVADKTGGGSYGANNDAGVVWTEEGVPLVLVVMTTR -PEQDAAYDHALIVEATRLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia beijingensis TaxID=95162 RepID=UPI000835C7DE ----AATSFTELESEHAARLGVYAIDTGSGRTV-AHRDAERFPMASTFKGLACGALLRDHP -LSTGYFDQVIRYSRSELVANSPVTEKHADTGMTVAELCDAAITVSDNTAGNQVLKLLGGP -EGFTAFLRSIGDTTSRLDRWETELNSAVPGDERDTTTPAALAADYRGLVVGDILAEPERA -QLKSWLIASKTGADRIRAALPAGWAVGNKTGSPAYGGALDVAVVWPPGRDPFVIAVLSTK -AEQNAEADGPLVAGAARAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Cryptosporangium arvum TaxID=80871 RepID=UPI0004AD4322 ---DTRDALRRLESTYDARLGVYAVDTGTGRTV-AYRADERFAYASTYKALAAAAVLDRTD ---PADLNRVVRYTAADVVDGSPVTAEHAGRGLPLGRIAEAAITKSDNTAGNLLFRELGGP -AGFERELRCLGDRVTSADRLEPALNGAVPGDVRDTSTPRALAADLRAYALGDALDVADRG -RLVGWLRGNTTGAELIRAGVPAGWIVGDKTGAAEYGTRNDIAVLWPPSGAPIVLTVLSRK -TDADAKYDNALIADAARVVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1022 TaxID=1463880 RepID=UPI0004C016B4 -----QAELAELERRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKVFAAAAVLRDHG --GCAPLDRVVHYPPHDLMPNSPRTEENQVTGMTVADLCAAAIRYSDNAAGNLLLREVGGP -AGLTRFLRSLGDAVSRLDRWEPELNTAVPGDPRDTTTPEAIAGSLERVTLGRALADADRE -RLVTWLKGTATSADRFRKGLPGDWVVADKTGTGDYASAHDIGVAWTTRGTPLVLAVLSGK -ATPDAPVDQALIADAAAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=A0A2P1WNA1_9BACI ---KLDEEFAALEDDFDAQLGVFALDTGSNQTI-AYRAEERFAFSSTYKALAGAFVLKQNT ---LEELNEVMTYTEDDLVPYSPVTEKHVDTGMTLLDIGEAAVRTSDNTAGNLLFEALGGP -AEFEEALREIGDDVSQSDRYETELNEFNPEDTRDTSTPKALATNLKKFVVGDLLPDEKRE -LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPPDREPIVIAIMSRH -DTEDTDYDDALIAEAAKVVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. RB20 TaxID=2585198 RepID=UPI001295102B ---ELSGRFGALESRFGARLGVFALDTGSGHTV-EYRADERFAFCSTFKALEAGAILTTAD ---AAALDRRITYTATDLTEYAPITRQHVADGMTVRELMDAAVRYSDNTAANLLFGQLGGP -AGFQRALRSLGDQVTRSDRLETALSDATPGDPRDTSTPRTFATDLRAYVLGTVLSADNRA -LLTTMLRTNTTGTGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPIVLAVMSTR -HNHDDSFDNALVAQATNAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Xenorhabdus sp. NBAII XenSa04 TaxID=1429873 RepID=UPI000645699F ---QIINQLIALEKSANGHLGVFLINTADNSTI-GYRANERFPLCSTSKFMAASALLKKSE -KDENLLNQRINYKQSDVVEYSPITEKHIASGMTLAELSAATLQYSDNTAMNLLLDQLDGP -RGLTKFARTIGDNKFRLDRKEPELNLVKPGDERDTSTPQAMAESLYKLTLGNMLATNQRV -QLAEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNRAPLVLVTYFTQ -PGKNAKARRDVLAEAAHILIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=UPI0006EB67B7 ----ATGDFEELERTYGARLGVYAVDTGSGREV-AHNDDERFAYASTFKAFAAAAVLRAYS ---PSGMDEVIMYSGDDLVAHSPVTEKYVGTGMTLRELCDAAVRHSDNTAANLLFDALGGP -KGLASALEEVGDTVTRVERREPELNQWAPGSTRDTTTPRAWADALRAFVLGDELGGRERA -QLTKWLRTNTTGDALIRAGVPEGWVVGDKTGGGGYGVRNDIAVVWPPDAAPLVMAIMSNR -GTEDAGYDDQLIEEAASVVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PpalLS-921 TaxID=1839772 RepID=UPI000B87CC51 ------------EAEFDARLGVYAVDTGTGREV-THHADERFAYASTFKALAAGAVLRTYK ---VSGMDRVITYSEDDLVPNSPVTEKHVGTGMTLGALCDAAVRYSDNTAANLLLDQLGGP -KGLGALLAELGDGVTRMERREPELSRWVPGSTRDTTTPRAFAENLRAFALGDVLGDAERA -RLTRWLRTNTTGDEVIRAGVPDNWSVGDKTGSGGYGIRNDIAVLWPPDRAPVVVAVLSNR -DGEDDAYDNRLLAKAAAVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AmelKG-E11A TaxID=1100822 RepID=A0A1C6PUJ9_9ACTN ------DELKALERKFDARLGVHAVDTGSGREI-AHNDRERFPYASTFKALAAGAVLREQS ---PSGMNRVVEYSEDDLIPHSPVTEKHVRTGMSLSALCDAAVRHSDNAAANLLFDELDGP -EGLDEVLEEVGDDVTRMVRREPELNRWAPGETRDTSTPRALAGSLRAFVLGDALGKDDRA -TLTKWLRTNTTGDALIRAGVPEGWTVGDKTGTGSYATRNDIAVVWPPGGAPIVMAIMSSR -DEKDAVHDDKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Amycolatopsis decaplanina TaxID=208441 RepID=M2YH32_9PSEU ----------ELEKKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLRRNP ---LSHLETRVSYSRDDLMEHAPVTGRHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -AELTAFTRSLGDTVTRMDRIEPAITEAAPGDLRDTTTARAFAADYRKIVLGDALTADKRD -FLRDLLQRNTTGAERIRAGVPSGWTVADKTGTGAYGTLNDIAVVWPPGKAPIVVAIMSGK -AAKDAPYDQALLAESAKYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Y-H1 TaxID=2485167 RepID=A0A4V2VM37_9BRAD -----PAELEAYERDTGGRIGLYAENLATGQKF-TWRADERFVMCSTFKASLAACVLARVD -GGEEQLATMIPYGKADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSAQSRL -QLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG -GTPNAAQIATLFAQIGRMVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WZ.A104 TaxID=2023771 RepID=A0A2A4KTP2_9ACTN -----TRAFAALEKEYTARLGVYAVDTGSGRTV-AHRDGERFPYTSTFKALAAGAVLHKHG ---LSGLEHVVTYRREDLVDYSPVTEKHVATGMSLGDLCDAAVRYSDNTAGNLLFDALGGP -RGLQTVLAGLGDDVTRMERRETELNEWSPGATRDTSTPRALAEDLRAFVLGDVLGRPERA -RLTQWLRTNTTGDELIRAGAPKGWTVGDKTGAGGYGTRNDIAVVWPPDAAPLVLAVLSNR -KDAKAAFDNTLIAKAASVAV--- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 94 TaxID=2135633 RepID=A0A495HY39_9BURK ---EWNEALASIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAGDVVAYSPVSGPRASDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR -STAKPEQRDAAIAQVARAVAT-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0N1K823_9ACTN ----TEGAFVELERKYGARLGVYALDTGSGRTV-THRSDERFAYASTCKALLAGAVLDRNS ---LRRLDRLVRYSRDDLISNSPITERHVATGLTLRELCDAAVRYSDNAAANLLFRELGGP -RGLQDALRALGDDVTRCDRYEVALSDAVPGDLRDTSTPRALVDDLRAYVLGSALPADKRA -VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAIAWPPGAAPIALAVLSRR -DAKNAESDDALLARAAEVAF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ACT-1 TaxID=1609288 RepID=G0PXB8_9ACTN -----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALRGPERA -RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TTADADHDNTLIAKAASAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SM1 TaxID=402229 RepID=UPI000CD54203 ------------------RLGVYALATGTGATV-VHRADERFAFCSTLKTLAAAAVLDRRT ---LARLDERVRYTRDDLVDYSPVTEKHTATGMTVRDLCDAAVRYSDNTAANLLLRDLGGP -RALTAHLRGLGDPVSRLDHFEPELNGNPPGDPRDTTTPRAVATDYRDLVLGNALPPAKRA -LLTDWLVRNTTGDRRIRAGVPRGWKVGDKTGTGEWGRANDVAVLWPGRGAPLVLAVLTDR -PGRDADPSDPLIAEATRRV---- ->[subseq from] Beta-lactamase n=1 Tax=Actinopolyspora xinjiangensis TaxID=405564 RepID=A0A1H0WUJ9_9ACTN -----HEDFRRLEHEFDARLGVYAVDTATGREL-SYRADERFAYASTHKALAAGAVLRRTS ---LEGLDEPITYDRADLVTYSPITKEHVDSGMSLRSVLDAAVRYSDNTAANLMFDELGGP -EGLSAALREIGDTTTHVDRIEPDLNATEPGDIRDTSTPRALATSLRAFTVGNALPKDERA -LLNRMLRNSTTGDELIRAGAPDSWRVGDKSGAADYGTRNDIAVLWPPEGAPVVLAVLSDH -PSRDAEYDNALLARAAETALREf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces catenulae TaxID=66875 RepID=UPI0004BF5492 ----FAQDLKELERKFSARLGVYAIDTGTGREV-AYRDGERFPFNSTFKALAAGEVLKQRT ---LSGMDDVVHYSQDDLVPNSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDKLGGP -KGLNAALKKLGDDVTRMERPEPLLSTWDPKSTRDTTTPRALAKDLRAYVLGKALRPAERA -QLTTWLRTNTTGDTLIRAGVPKGWVVGDKTGMGSYGTRNDIAVLWPEHSSPIVVSILSSR -EAEDATPEDKVIAEAASVVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC01280 TaxID=2487424 RepID=A0A3R9WC70_9ACTN ----AARAFGDLERKFDARLGVYAIDTGTGRTV-THRPDERFAYASTCKALLAGAVLDRNT ---LRQLDRLVRYGRDELVSNSPVTERHLATGLTLRELCDAAVRYSDNAAANLLFRELGGP -RGFQDALRALGDDVTRCDRYEVALSDAVPGDLRDTSTPRALAADLRAYVLGTTLPADKRA -VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGTGGYGTRNDIAVIWPPGAAPIALAVLSRR -DTEGAERDDALIARATEVAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TRM68085 TaxID=2600619 RepID=A0A5N5ELW9_9ACTN ----TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLAGAVLAKKT ---LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGTALPAEKRA -VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIVLAVLSRR -DIKNAETDDALIAGAAKVALGAf ->[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Accumulibacter sp. 66-26 TaxID=1895689 RepID=A0A1Q3VPV3_9PROT ----LNARLRELEAAAGGRLGVHFLDTASGREY-GYRAHERFPLFSSFKLLAGALVLHRVD -AGQESLARRIPYARDDLVEWSPVTERHADGAMSLGDLCEAAITTSDNTAANLILASFGGP -AGLTAYARRLGDAVTRLDRNEPDLNDPHPTQPLDTTSPGAMSRTVQQVVLGDALSAQSRR -QLQHWLLDNTTGGRRLRAGLPADWRIGDKTGTGKT-GANDIGVVWPPGGAPLVVSAYLAD -SDADIRLREATLAGVGG------ ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0005FA91FD --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE -QKKLNLNATTTVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLHQIGGP -EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLSPESQQ -RLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMAQRNRVINQVANLVFQQf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. SRB_336 TaxID=1969380 RepID=A0A328M4H5_9BACI ------ARLAALERRHGGRLGVAVVDTGNGRRI-AHRAEERFLMCSTCKLPIVAAVLARVD -RGAEQLGRRVVFGKSALLSHAPVCERRVGAPMTVAELCHAAITVSDNTAANLLLASLGGP -AAVTAYARSLGDDTTRLDRDEPKLNLASPDGLLDTTTPRAMLADLQTLLLGQALSGASRR -QLIAWLCASTTGLHMLRAGIPPAWRVGDKTGRGPRLETNDIAIVWPPGRQPLLVTAYYAE -SRATDAECTAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0004C35D62 ------SQFAALERKHGARLGVYVLETGTGASL-AYRADERFAFCSTFKALAAAAVLHQNP ---VSHLGKRVTYTGADVNSISPITKDHIATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -ARFTAYLRRLGDTVSRMDNYEPELNRDRPRDPRDTTTPRAIAADYQKLVLGEALSAGKRA -LLKDWLVRNTTGAKRVRAGLPKVWTVADKTGTGDYGRANDIAIVWPPHAAPLVMAIMSDR -PGYHTPPKDSLIAEATARIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinopolyspora halophila TaxID=1850 RepID=UPI0003622944 -------RFDRLEQRFDARLGVYAVDTATGEEV-THRADERFAYASTHKALSAGVVLRRNS ---IGGLNRRIHYSASDLVTYSPVTKKHVDTGMTLREVMGAAIRYSDNTAANLLFREIGGP -AALQGALRGIGDTTIHVDRTEPELNRTSPGDLRDTSTARAMAESLRKFTTGDVLSPDKRA -ILNEMLRTAQLTGDLIRAGVPSGWEVGDKSGAADYGTRNDIAVIRPPGRAPIVLAIMSDR -QDEDADYDNALIAQTARQVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TND4FH1 TaxID=1907401 RepID=A0A4R8L9R5_9GAMM ----AAGRLAALERKYGGRLGVSMLDTGSGQQA-GHRTDERFLMCSTFKLLAVATVLGRVD -KGREQLDRRITYGKEVLLAWAPVTSRHVGADMTVGELCEAAITMSDNTAANLLLASLGGP -AVVTAFVRTLGDPLTRLDRIEPELNVGGPGDLRDTTTPAAMLGDMRALLLGDALAAVSRQ -RLIGWLRACSTGLDKLRGGLPAGWDAGDKTGSGAQGESNDVAILWPPRRAPMLVTAYYAP -ATPDKATSVRVLAEVGRITA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia paucivorans TaxID=114259 RepID=UPI000312C307 -----DQPFAALEAEHGARLGVFAVDTADGRSV-AYRAGERFPMASMFKGLACGALLREHP -LASGFFDQVIRYPRTDLVEYSPVTEQHVDTGMTVAALCEAAITRSDNTAGNQILKLLDGP -AGFTAFLRTLGDDVSRLDRWETELNTAIPGDERDTTTPSALAADYRALVVDDGLAEPERT -RLSSWLIANTTGDSRIRAGLPADWTVGDKTGSSAYGCALDIAVTWPPGRAPIVIAVLTAK -SEQDAEPDNALVAAAARTAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. Alg231-36 TaxID=1922224 RepID=UPI000D55AC58 ----VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGDERFPMNSTFKAFLCAALLDAAS -NGTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP -EGVTAFLRGIGDDISRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDETLAADARA -KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ -TTAAFEARNKAIAGIAQAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0013B731A0 -----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVDTGMSLGALCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALGGPERA -RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TAADADHDNTLIAKAASAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00035E3026 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADQRFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEAIPGDRRDTSTARALTEDLREYAVDDALDPTDRD -LLNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEADASFDNALIAEAAKVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-LD23 TaxID=2486417 RepID=A0A3M8VRP7_9ACTN ------GELKALEREYDARLGLYAIDTGTGRQV-AYRDGERFGFHSTFKALAAGAVLRKYS ---LSGMNKVITYSRDDLIDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDAIGGP -KALEREVRRVGDDVTQVERIEPELSKWVPGDTRDTTTPRALAKDLRAFALGDVLRKPERA -QLRTWLKTNTTGDALIRAGVPKGWVVGDKTGSGYYGARNDIAVVWRPDAAPIVMAVLTNR -GAKDDVHDDKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 'Ferrero' TaxID=2033654 RepID=A0A2A5NSH2_9MICO -----AAAFAALEQRFRARLGLVVLDPRDGTSV-QYRADERFPFASTNKVFIAAAVLDRSS ---TADLDAVVHFDRSDLLAYAPVTERHLDTGMTVRELVDAALRYSDNTAANLLVERLGGP -AAVQRWLRSTGDRVTRVDRVEPDLNTAVPGDPRDTTTPLQFAADLRAVLLGDVLSPAARA -LLRSTMAANTTGDATIRAGVPSGWEVADKTGTGERGVRNDIGIVTPAGGDPLVVVVTTRT -DDPDAAPSDALVAAATRA----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W5T2X4_ECOLX ------VKVIDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTMGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTT- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia gamkensis TaxID=352869 RepID=UPI0007A398F8 ----ASTSVADLEARYGAQIGLFAVDTGTGRTV-THRADERFPFLSTFKALAAAALLRSHP -LDTGYFDRVIRFDEADLVEHSPVTSAGVVDGMTLARVAEAAITRSDNTAGNLLLREIGGP -EGLTAFLRTLGDPASRLDRWETELNTAIPGDERDTTTPAALAADYRASALGDALGAPERD -QLVAWLKANTTGGERIRAGLPANWVTGDKTGTGSYGSANDVAIVWPEGGAPIVIAIMSRK -SDADAEANSDLLVEVTKVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 840.1 TaxID=2485152 RepID=A0A3N1SCA7_9ACTN ---RTERAFRDLERKFDARLGVHALDTGSGRTV-THRPDERFAFASTCKALLVGAVLDKNS ---LRQMDRLVRYGRDDLVSASPITERHVDTGMTLRELSDAAIRYSDNTAANLLFHELGSP -YALQKALRSLGDEVTRCDRYETALSDATPGDPRDTSTPRALATDLRAYVLGSTLPADKRA -VLTDLLRRNTTGDHTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR -STKDAERDDALIAGAAKVAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF15084 ------HSFVKLEKEYDAKLGIYALDTGTNQTV-TYRSDERFAYASTHKVLAVGALLQKKS ---IEDLDQKIKYTSKDLVNYNPITEKYVGTGMTLKELADASIRYSDNTAQNLILKQLGGP -SEFKKSLREIGDSVTNPERFEPELNEVQPDDTRDTSTAMALATSLQTYALSDILPIEKRS -FLIDLMKRNTTGDNLIRAGVPAGLEVADKTGSGSYGTRNDIAIIWPPNKNPIVLAILSNH -AKEDAKYDDKLIANATKIVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=A0A5B8JW12_PAEPO ------VVFKQLETKFDARLGVYIIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDLRDTSTPNALANSFKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTEDAEYNNALVAEAAKAAFK-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 100 TaxID=2135635 RepID=A0A3L9YQ13_9BURK ---AWNDALASIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGNERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSPMSRA -WLQRWLVETSTGDKRLRAGVP-GWRVGDKTGTAGSGTANDIGVLWPQDGAPVLVTCYLTR -SKASPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces xiaopingdaonensis TaxID=1565415 RepID=UPI00030010B6 -----KREFAALERKFDAKLGVYALDTGSGKEI-AHRPDTRFAHASTFKALLAGVILEQTS ---AADLDERVEYTKKDLPEYSPITERHASDGMTLRELCDAAVRHSDNGAANLLVRHLGGP -AELQKALRASGNRVTHIDRYETDMSAAEPGDVRDTSTPRALADSLRTYAVQNTLPAKKRT -MLTDWLKRNTTGDDLIRAGAPKGWKVGDKTGNGGYGTRNDIAVVWPPKSDPIVLAVLSKR -DTKNAEHDDALVADAAEVALE-- ->[subseq from] Beta-lactamase n=2 Tax=Nocardia africana TaxID=134964 RepID=A0A378WL71_9NOCA ----ALAEFHDLEARLHGRLGVYALDTGTGRAV-EYRSDERFPYCSTFKALAAGALLSTLP ---PAELDRRITYTRADLVPNSPVTERHVDQGLTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAADLRHYVLDPSVAAGDRD -VLTGLLRANTTGGALIRAGVPAGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDTAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. B2-3-4 TaxID=2589959 RepID=A0A503WKT4_9RHIZ -------KIRRIEAKSGGRLGVACRIAGTTTQF-GYRENELFPMCSTFKALMAALVLHRVD -GGIEQLERVIKVPHNAVIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLASFDGP -PQLTAYLRSIGDTVTRLDRIEPELNESVPGDPRDTTSPLAMIEDYERLALGDALSPKSRK -QFVDWLVANKTGDERIRAGLPKGWRCGDKTGTGARGSTNDAAVIWPASGNPILISVYLTG -TKQALAKRNATIASVSRALVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A222U9C1_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIY--- ------------------------ ->[subseq from] Beta-lactamase family protein n=2 Tax=Rhizobium TaxID=379 RepID=L0LX26_RHITR -----EAQLAALESKHPGRICVSILDMASGKRV-EHRSGERILMCSTFKALTAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATEPNVGDNMTVGELCEAAVTLSDNTAANLLLASFGGP -EAITTFCRSIGDEITRLDRTEPTLNYDIPNDERDTTTASAMLENLRRLMFTDVLTPASRS -QLAAWLITNKTGDARLRAGLPKDWLVSDKTGTNGHGNANDIAVLWPSNRAPIIVTAYCEI -PAITADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavidovirens TaxID=67298 RepID=UPI0003F732EE -----ARELKELEREFDARLGVYAVDTGTGREV-AYNDGERFPYASTFKALAAGAVLREYA ---PSGMGRVIKYSRDDLIAHSPVTEKHLETGMSLSALCDAAVRFSDNTAANLLLDQLGGP -RGMDAVLEELGDDVTRMERREPQLSQWDPRSTRDTTTPRALAGDLRAFVLGDALGKGERA -QLTKWLRTNTTGAELIRAGMPKDWVVGDKTGTGSYGARNDIAVVWPPGTAPIVVAIMSNR -SEKNADHDNELIAEAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004854FA6 ---DLHHELRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASYDNALIAEATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. CICC 11023 TaxID=2545717 RepID=A0A5N0EPA2_9NOCA ----SAAELAALEKKYDARIGVFAVDTGSGKTL-TARADERFPFLSTFKGLAAAALLKAHP -LDTGYFDRVIHYTDADLLSYSPVTKTKVAEGMTVAQLAEAAITQSDNTAGNLLLRELGGP -QGLTGFLRGIGDQVSHLDRWEPELNTAIPGDERDTTTPAALATDYRALVVGDALGAPERA -RLTGWLKANTTGDKRIRAGVPAGWSTGDKTGTGDYGCAHDAAVTWPDGSAPLVIAIQTCK -SVKEAESSNDVIADATRVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768) TaxID=1214101 RepID=K4RBG2_STRDJ ----ATARLRALEEEHGGRLGVYAHNLATRRTV-RHRADELFPMCSLFKTLAAAAVLRDLD -RDGEVLNSRLHYTEADLVDVPDVIREHLSDGMTVAALAELAITHSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRVTDTTSPAAIGRTYGRLVLGDALNRRDRE -QLTEWLLRNTTSTARFRAGLPPAWTLGDKTGSGSYGTANDVGVAWTETGAPIVLSVLTTK -PEQNAAWDNALVAKTAKVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID8016 TaxID=2706098 RepID=UPI0013D99A75 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDRRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGGALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=UPI00130E46EA ------RELAKLEAMSGGRLGLFVRDTATGQQA-GWRSQERFPLCSTFKTLLAAHALNEVQ -QGRLPLDRTFQYRKADLVPWSPITEKHADTDMTLQQLCEAAVVVSDNTAANLLLKATGGP -EGLTAWLRLMGDHQTRLDRFEPELNTAVKGDERDTTTPAAMLGSLQKLLVGTVLPEAERN -LLLQWLVASRTGDKRLRAGMPADWKAGGKTGSGENGTANDTLIVWPTTKKPLLVTAYFTG -SQLDAAGRDAVLAQVGDAVK--- ->[subseq from] Beta-lactamase n=2 Tax=Caulobacter sp. (strain K31) TaxID=366602 RepID=B0SWD0_CAUSK -----SRSMAALEARSGGRLGVAVLDTAGGKAF-AYRGDERFAMCSTFKALIAGFVLKRVD -QGKERLDRRITYGKGVLLAHSPATEKHVGDGMTVGELCEATITLSDNAAANLLLRTFGGP -PALTAFLRGLGDKVTRTDGYEPGINVVEPGEVHDTTSPNAMLATLRTLTLGSALAPASRQ -RLVGWLVANQTGDKRLRAGLLAGWTVGDKTGSWGKGTTNDIAVIWPTGRPPLLITAYLAD -SRLDSDGRDAVIAEVARLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0014315680 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-CYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKEIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces griseoviridis TaxID=45398 RepID=A0A3S9ZI84_STRGD -----VDRLRALEEEHGARLGVFAHNVRTGRTV-AHRADERFPICSVFKTLAVSAVLRDLD -RDGEVLGRRVHYTEADLVGGSDRTREHLAEGMTVAELADVAIRYSDNTAANLLLRELGGP -TAVTRFARSIGDRVTRLDRWETELNSGEPGRVTDTTSPRAIGRSYARLVLGDALADRDRA -LLTHWLLGNTTSGERLRAGVPSTWTVADKTGAGDYGTNNDVGVAWTPDGTPVVLAILSTK -HVQDAEWDHPLVKEAASLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003615D6A ---DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASYDNALIAEATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A402CDY9_9NOCA --qSLDAKIDALEAQYATRIGVTAVDPASGAVY-NHRGDERFAMCSTFKAYASAAVLRKIE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTRSDNTAGNYLLREIGGP -QAITALARDLGDESTRLDRWETELNTALRGDPRDTTTPAGLAQGFRALLLGDALDAASRD -QLVDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rapamycinicus TaxID=1226757 RepID=UPI000EF80019 ---AVTGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALAAGAVLRKYK ---LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGV -KGLDATLEKLGDDVIQMERIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLDKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPDAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. OV198 TaxID=1882787 RepID=UPI000BE36FE1 ---DTRARLRELEARHGARIGAFAYNLRTEATV-RHRAAERFPGCSVFKTLAAAAVLRDLD -QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQNAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003614918 ---DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASYDNALIAEATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004839A97 ---DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASYDNALIAEATEVVIA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A0D4DHB7_9ACTN -----AGEFKKLERKFDARLGVYAVDTGTGREV-AYNDGERFAHASTFKALAAGAVLRKYA ---PSGMDKVIKYSKSDLVESSPITEKHIETGMTLRELCDAAVRFSDNTAGNLLFDALGGP -KGLDAALAKIGDDATRMERREPELNRWAPGEQRDTSTPRALAKDLRAFVLGNLLGKGERA -QLTKWLRTNTTGGELIKAGMPKDWKVGDKTGAGSYGTRNDIAVVWRPHAAPIVVAILSHR -NKAGAHYDNKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BD8133 -------RLRALEREFGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERVSYSTADLVTYSPVTEKHTADGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHVEPELNSNPPGDPRDTTSPRAIAADYRALVLGDALPAAGRA -LITDWLVRNTTGDRRIRAAVPRGWRVGDKTGGGEWGRGNDVAVLWPGGRPPLVLSVLTER -TDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Pantoea TaxID=2630326 RepID=A0A5M7NNI1_9GAMM --qSLNNQFEKLERQSGGRLGLAVIDTSDSAQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIHISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ -HDKSAAARKDVLTSAARVIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=A0A328MX27_9ACTN -----DQEFRRLEEQFGARLGIYAVDTGTGRTV-EYRADERFAYASTWKALAAAEVLDGTT ---DAQLDRVVRYSTRDLVAHSPITEKHVGEGMSLRALADAAVRYSDNTAGNLLLRHLGGP -AGFEAKLRALGDTVTDVARYETALNEGTPGDKRDTSTARALAGDLRAYTVGVALEPADRD -VLRARLRGNTTGAALVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSSR -DRKDATPADAVIAQATRVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella hinzii TaxID=103855 RepID=A0A448LQJ4_9BORD ---DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA -RGEDDLSRPMRLSAADIVDYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP -PGVTAYARALGDGATRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDALPAPERE -RLRDWLMQCRTGQQRLRAGLPAGWSLGHRTGAGGHGTCNDIGVAWPTPTTPVVISVYLTE -SPLDLPGRERVLAEAARILAH-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. MG34 TaxID=2600296 RepID=UPI001372B34C ---KLDEQFAVLEDDFDAQLGVYALDTGSNQTI-AYRAEERFAFSSTYKALAAALLLEQNE ---MEELNEVITYSEDDLVTYSPVTEKHVDTGMTLLEIGEAAVRTSDNTAGNLLFDALEGP -AKFEEALRQIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLTDEKRE -LFTDWLQGNATGDTLIRAGAPEGWVVGDKSGAGTYGTRNDIAVVWPQDREPIVIVIMSRH -DTEDADYDDALISEAAKVVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VLD3_9GAMM ---ALDDALAALESAAGGRLGVALLDTGTGRRF-GRRDEARFPMCSTFKALLAGAVLHAVD -RGRVRLDQRVDIGAEDLVTYSPYVDTRVADGARVDALCRATVTLSDNAAANLLLPLVGGP -PGLTALLRELGDPVTRLDRWEPALNEAAPGDPRDTTSPRAMVDSLQRLLFGTALHPPSQA -VLAAWLIENRTGDARIRAGVPADWRVGDKTGTCGAGTAADVAVLYPPGRAPLLLAIYVHG -ATLDGPAIDALHADATRLLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomonospora sp. PA3 TaxID=2607326 RepID=UPI0012DD81B4 -------DFRKLEKEYDATLGVYALDTGTGETV-AFNAGDRFLFCSTHKVFSAGAVLDQTP ---MEDLDKRITYTEDDLLEWAPITEKHVDEGMELLDVIDAAVRYSDNTAANLLFEELGGP -AALQEEMRAIGDETIRFDRIEPDLSYTEPGDLRDTSTPQAMVSSLRAYALGDVLPQEKRE -ILVDMMVRNTTGDDTIRAGVPDDWTVGDKTGTGNYGTRNDIAVLWPPEEEPIVVAVMSTR -DTADAEHDDALLAESAEVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5NET2_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPK------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. J31 TaxID=935851 RepID=UPI0004046DEB -----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD -RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP -AALTAFLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLRRCVAGAVLAPASRL -QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG -SRVDSAARDAVLARAGQLAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC06614 TaxID=2487416 RepID=A0A429S6E7_9ACTN ---DITARLRALEGEHAARLGVFAYDTATGATV-AHRADERFPMCSLFKTLAAAAVLRDLD -HDGEYLARRVRWTAEDVRAHAPVTGERANLELTVGELCAAAISFSDNTAANLLLRDLGGP -TAVTRFSRSLGDPVTRLDRWEPELNSAEPDRGTDLTTPRAIGRTYARLVLGRALERPDRE -RLTGWLLANTTSGKRFRAGLPAGWRLADKTGGGSYGTNNDVGIAWPPGRPPVVLAVLTTH -ASPTAAADDALVAEAARLVS--- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5PQJ2_9BACT -----NANFAQLETRTKSRIGVAAVDLSTNRRV-DYRAEERFLMCSTFKVLAAAGVLKRVD -ENKEKLDHFVTYGEAQLLSYAPVTRAHVKEGLTLETLCAAAVEQSDNTAANLLLESIGGP -EKVTELARSLGDKFTRLDQTEPELNVAKPGQDDNTTTPAAMCADLQRLLTSDFLTTASRT -KLEGWMRQNQTGSKLIRAALPSDWQVGDKTGRSGDGATNDIAIVRPPGGGPIFLAIYTVD -PSETPEAREKLVAEVAKTAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces orinoci TaxID=67339 RepID=UPI000D657AE3 ------AAFKGLEQRFGARLGLYALDTGTGREV-TYRADERFAHASTFKALATGALLRHAS ---DADLEQVVNYGPRDLQKWAPVTAKHTGTGMRLRELADAAMRYSDNTAANLILDRLGGP -SGLQRQLFELGDSTTNINRPEPDLNEATPGDPRDTSTPRALAADLRRFVLGDALSPGRRR -LLTDWLMGNTTGGPYIRAGVPAGWKVGDKTGNGGYGTRNDIAVAWPPSGRPVVIVILSDR -AKANASSDDSLIADATKAAVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Variibacter gotjawalensis TaxID=1333996 RepID=UPI000BBAC6DB ----FEDVMAEIEKSTGGRLGVGLLDLQTDKTA-FHRGDERFPMCSTFKFLLAAAVLAKAD -AREENLARRVRFEKAELLPHSPMTEQRAGDALTIAQLCEAAVTQSDNTAANLLLASLDGP -TGLTAFARKIGDTITRLDRTEPDLNDVAPGDERDTTSPRAMAEDMRKILVGDVLKIGSRE -QLSTWMRESATGKNRIRASLPMGWSAGDKTGTGPRGTSNDIAIMSPSGRQPIILTVYLTG -ATVDQTKQEAAIATVATAVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia jinanensis TaxID=382504 RepID=UPI0012E3BC9C -----TQQFADLEAAHGARLGVFVLDTTDGRSV-SYRDGERFPMASTFKGLACGALLREHP -LSSGFFDRVIQYPRTDLVANSPVTEQHVDTGMTVAALCEAAITVSDNTAGNQILKLLDGP -AGFTAFLRTLGDNTSRLDRWETELNTAIPGDERDTTTAAALAADYRALVVGDSLAEPERA -QLSAWLVASATGGNRIRAGLPAGWTVGNKTGSPAYGSALDVAIAWPPGRAPIVLAVLTTK -SEQDAEPDNALVAAATRAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus senegalensis TaxID=1936063 RepID=UPI000A3142DB ---STNDVFRQLEDEYDARLGIYALDTGTNQTV-KHREDERFAYGSTHKALSVGVLLQQNN ---LNELDQTITFTYDDLVNYNPITEKHVDTGMTLREISDAAIRHSDNTAANLILEQIGGP -EGFKEALRKIGDDVTNPERIEPELNEVEPGETQDTSTPEALATSLQAFTTGDALPSEKQD -LLIDWLKRNTTGDALIRAGVPEGWEVGDKTGSASYGTRNDIAIIWPPNGDPIFLAVLSSR -DQKDAESDDELIEKATEEVF--- ->[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella sp. AETb1-6 TaxID=2692210 RepID=UPI001367CDAA ---ALGKRLAELEARHKGRIGVAIHNLATGARL-GHRADERFLMCSTFKALLAAHILARVD -RGEEALDRRIVVKTTDLVDWSPVVEKHVGDAISVAALCEATITLSDNAAANLLLAASGGP -EAVTAFLRGFGDTVTRLDRTEPTLNYDSPADERDTTTPAAMTDTLHRLVLGDVLSPQAKA -QLAAWLVMNKTGDTRLRAGFPANWMTGDKTGTNGAGNANDVAIAWSPDRGAIVVTAFVEM -PGISGDDRNAIIAEIGRVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia alba TaxID=225051 RepID=UPI00104D921A -----SATFADLESKYGARLGLSVLDTGSGAAL-AYRADERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTPADLVVNSSETGKHLDTGMTVAALCDAAITLSDNTAGNMLLRLLGGP -AGFTAFLRTLGDPVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERA -QLATWLKASKTGATRIKAGLPADWIVGDKTGSPAYGSALDVAVAWPPNRAPLVLAVLTTK -PKRDAEPANDLVAEATEVAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia pseudosacchari TaxID=1646340 RepID=UPI000A369AD2 ----------LQEERLSARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFAQSDVVTYSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP -AAVTRFFADSGDSVTRLDRAEPELNSAVPGDVRDTTTPLAVSHTLQKLALGSALTPASRA -QLVQWMKEDKVAGALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD -TKATMAQSNDAIARIGKAIFS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=A0A1V0I6E5_9VIBR --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNSTTKVKESDLVTWSPITEKLTGQEVTVQKACEATMLMSDNTAANIVLYQIGGP -EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. 13-12-16 TaxID=1570823 RepID=A0A1X4ICE4_9ACTN -----VRRLRELEQRHSARLGVYARDTATGRTV-RYRADERFPMCSLFKTPAVAAVLRDLD -RDGEFLAERIRYTEKDVTDYAPVTGENLASGMTVAELCDATIRHSDNAAGNLLLRELGGP -AAVTRFCRSIGDRTTRLDRWEPELNSAEPWRETDTTTPYAVGRTYARLTLGTALAPGDRE -RLTGWLLANTTGDAKLRAGLPADWAVAEKTAGGKYGTNHDVGVALPPRRAPLVLAVLTTK -REPDAAPDNPLIAETAALLAE-- ->[subseq from] class A beta-lactamase n=2 Tax=Bacillus aciditolerans (strain JCM 32973 / CCTCC AB 2017280 / YN-1) TaxID=72581 RepID=UPI00140546B1 ---TTDEEFTQLESKFDARLGVYAYDTETEKSV-VHREDEKFAFASTYKALAAGAMLQQKS ---INELDEIITYTKDELVTYSPVTEKHVDTGMSLKDIAEAAIRYSDNTAGNLLFNEIGGP -VGFETALREIGDMVTESDRFEPDLNFTAPGNSRDTSTPRALAQSLQTFVVSDILPSEKRA -LMTDWLVGNTTGDTLIRAGVPEGWVVGDKSGAASYGTRNDIAIVWPPERDPIVIAILSDR -SSEDATYDDTLIAEATKIVIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. YK2 TaxID=1860096 RepID=A0A1E4Y600_9RHIZ -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLIDYSPATKPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSIGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRFLFTDILTAASRS -QLAAWLIANKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKRAPIIVTAYCEI -PTIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium zhanjiangense TaxID=1325107 RepID=UPI0010088FD3 -------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTISRLDHNEPELNRSRPGDPRDTTTPAAMVGNLRRLVLGEALSPTSRA -QLTEWMVNCKTGANRLRGGLPAGWRIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG -GTPSAAQIAAAFARIGRMA---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD75FBE -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPTTKPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTDVLTPASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000368AAFB -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. S-62 TaxID=2653123 RepID=A0A5J4LXK3_9RHIZ -----EAQLAALESKHPGRICVSILDLARGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLVDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSMGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRLLFTDILTAASRS -QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKHAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048A8D4A -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0004BB555A ------SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAANVLARVD -RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVTGEALSPASRV -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPSAAQIASAFARIGRMVAE-- ->[subseq from] TEM family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000672211F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIL--- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9002 TaxID=2184558 RepID=UPI000F5E27BA ----ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALDKPVKYGNADLLDYAPVAREHVERGMTVDELCAAATVWSDNTAANLLLELLGGP -AGWTRFARSIGDDASRLDRTEPALNSAIPGDPRDTTTPDAMLANLKMTLLGTVLSESSRE -KLQSWMLSGTITDTLLRAGVPLEWRVGDKSGAGKNGTRNDIGIIFPPDASPILAAIYYTE -STGSLASREEVIAEVGGIIAETf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rapamycinicus (strain ATCC 29253 / DSM 41530 / NRRL 5491 / AYB-994) TaxID=1343740 RepID=A0A0A0NSI4_STRRN ---AVTGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALAAGAVLRKYK ---LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGV -KGLDATLEKLGDDVIQMERIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLDKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPDAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsaceae bacterium YIM 96095 TaxID=2487137 RepID=A0A3N0EGJ2_9ACTN ----YAAEFERLEQEFDARLGVYARDTGTDAEV-THRADERFAYASTFKPLACAAVLERRS ---MAEMEETVTFGSEELVEYSPITEERVDTGMTLVEVCDAALRHSDNTAANLLFAELGGP -EGLQEALEELGDDVTRVEREETALNEAEPGDIRDTTTPEAFAANLEKYVLGDTLPEGKRA -LLREMMVGNTTGDDLIRAGVPEEWEVGDKTGSPGYGGRNDIAVVWPADGEPIVLAVMSSR -DEEDAEYDDALVAEATEVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. BK463 TaxID=2587008 RepID=UPI000DE17B72 -----EAQLAALESKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD -QGEEKLDRRIHYRKSDLIDYSPATEPNAGENMTVGDLCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLESLRQLLFTDVLTPASRS -QLAAWLITNKTGDTRLRAGLPKNWLVGDKTGTNGAGNANDIAVLWPANRAPIIVTAYCEI -PEIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Edaphobacter aggregans TaxID=570835 RepID=UPI0005594BBB ---DLAATLAALEQKSKGRLGVAIL-FPDGRRA-TYRADERFPMCSTFKFLAAALTLQRVD -QNKERLNRTITYSKSDLVTYSPETEKH--TSMTVASLCQASLTLSDNTAANLLLASFGGP -PAITAFARSLGDPVTRLDRTETTLNESTPGDPRDTTTPTAMLANLQKILFGNVLKPASRD -HLTRWMLANTTGKAKFVAGLPATWKVADKTGSGDHGSNNDIGVLYPPGDKPILITSYLTE -TTITTDERNAIHADVARSITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. KKS102 TaxID=358220 RepID=K0HTM3_9BURK ---AWNEALASIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGARAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPMLVTCYLTR -STASGEQRDAAIAQVARAVAT-- ->[subseq from] Beta-lactamase n=1 Tax=Leifsonia sp. ku-ls TaxID=2220072 RepID=A0A3D8N7T2_9MICO ------AALRGLEETYDATLGVYAVDTSTGRAV-GYRADERFAYASTSKALLAGAVLASVD ---DADLDATVRYTADDLVSYSPVTEGHVGEGMPLRDVIAAALRSSDNTAANLLFRQLGGP -DGLQRALRALGDTTTTVAREEPDLNEATPGDDRDTSTPRALAAALRSYAVGDALSPERRR -LLLDDMTGNATGAALIRTGVPADWTVADKSGAAAYGTRNDVAVVQPPGGAPIVLVVMSRK -QAKDAAYDNALIADAARAVATAf ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=A0A2A2MNL3_9VIBR --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNATTKVKESDLVTWSPITEKLTGQEITVQKACEATMLMSDNTAANIVLYQIGGP -EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQR -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces nanshensis TaxID=518642 RepID=A0A1E7LYQ6_9ACTN ----TDRAFAELERKFDARLGVYAVDTGDGRAV-THRPDERFAYASTCKALLSGAVLARKS ---LPQMERLVRYGQEEIISHSPITGKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGIGDDVTRCDRYEIALSDATPGDLRDTSTPRALATDLRAYALGPALPAEKRA -LLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAIVWPPGAAPIAIAVLSRR -DVKDAEPDDALIAGAAEVALEAf ->[subseq from] Beta-lactamase n=1 Tax=Kushneria marisflavi TaxID=157779 RepID=A0A240US94_9GAMM --qEVQGSIQALEQQHGGRLGVALMNVGTGAVV-SHRGNERFLFNSTGKVFIAAAVLAQVD -DGKASLDQRIEVKSSDLTGWTPITEQQLGSPMTIAELCQAAVAWSDNAAANLLIERLGGP -EHVTAFLRAIGDTTTRLDRTEPALNEDHEGDERDTTTPLAMMQTLRTLLLGEALSPASRH -QLAAWMIEGKTGDARLRAGMPTGWLVGEKTGTNSVGNAADIGIAWPSNRGAVIAIAYVYL -PQADKAQRDQVIAEIGQLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI000C168BE6 --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHSDDRFPMMSTFKTLMCANVLHLAE -QKKLNLNATTTIKESDLATWSPITEKLTGQEITVQKACEATMLMSDNTAANIVLHQIGGP -EQVTQFVRSLDDSVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLSSESQQ -RLLTWMKNNKVSDPLIRSVLPQDWSVADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMVQRNRVINRVANLVFEQf ->[subseq from] class A beta-lactamase n=1 Tax=Roseovarius tolerans TaxID=74031 RepID=UPI0009F6BE6A --dDLRQTVQDVEARIGGRIGYAVTDLNGGQEW-GSRPDERFPMSSTFKALLCGVILARVD -AGAEALDRRITFGRDDLVTYSPVTDWHLGTGMTVGELCHAAITMSDNTAGNLLLATIGGP -EGFTEILRDMGDATTRLDRWETALNEGAPGDERHTTTPRAALSTLQALLFGDMLTVASRE -QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPTPNHPVLVTIFMTG -ADAGMTDRNAAIAEIGAAIFA-- ->[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-35 TaxID=512030 RepID=H0BW75_9BURK ---EWNETLAHIERTAQGRLGVAMLDMGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD -QGRERLDARVHYAVADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDSITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVMWPPGGAPVLVTCYLTR -STAKPEQRDAAIAEVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia alba TaxID=225051 RepID=A0A4R1FYY6_9NOCA -----SATFADLESKYGARLGLSVLDTGSGAAL-AYRADERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTPADLVVNSSETGKHLDTGMTVAALCDAAITLSDNTAGNMLLRLLGGP -AGFTAFLRTLGDPVSRLDRWEPELNTAIPGDERDTTTAAALVANYRALVVGTALPEPERA -QLATWLKASKTGATRIKAGLPADWIVGDKTGSPAYGSALDVAVAWPPNRAPLVLAVLTTK -PKRDAEPANDLVAEATEVAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238WSL4_9ACTN ---KVTRQIGRLEATHHLRIGAFAIDTGNGRKV-SNRPDERFAFASTFKAMACGAVLRKAR -RDPGLLDRVIHYTKDDLVDFSPVTEKHVDTGMTVAALCHAAITRSDNTAGNLVLKQIGGP -AGLTAFFRSIGDTVSRSDRWETALNDWKPGEPRDTTAPRPWAGDLRALTVGDALVPADRK -QLIGWMKATVTGDKRIRAGLPKNWTVGDKTGTGDYGTANDIAIAWPPSGAPLVIVITTNR -FGVDDEADDEAVAQTARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BEB6DE9 --------------------GIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. KKS102 TaxID=358220 RepID=UPI0005BCFA2F ---AWNEALASIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGARAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPMLVTCYLTR -STASGEQRDAAIAQVARAVAT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces radiopugnans TaxID=403935 RepID=A0A1H9DHD0_9ACTN ------RDLRSLEREFDARLGVYAVDTGTGREV-AYNDDERFAYASTFKALAAGAVLRKYS ---PSGMEEVVEYSEDDLVAHSPVTGKHTGTGMTLRELCEAAVRFSDNTAANLLFDAVGGP -RGLDTVLEEIGDDVTRMERREPELSRWAPGETRDTSTPRAFAGNLRAFVLGDVLGEGERA -QLAEWLRTNVTGSGLIRAGMPRGWVVGDKTGTGGYGVRNDIAVVWPPAGAPIVVAIMSNR -DEEDAEHDDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=UPI000F5708FF --qSLDAKIDALEAQYATRIGVTAVDPASGAVY-NHRGDERFAMCSTFKAYASAAVLRKIE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTRSDNTAGNYLLREIGGP -QAITALARDLGDESTRLDRWETELNTALRGDPRDTTTPAGLAQGFRALLLGDALDAASRD -QLVDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000804E4A9 -----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHVATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALRGPERA -RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TAADADHDNTLIAKAASAAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. DOA9 TaxID=1126627 RepID=A0A0S6ULY2_9BRAD ------SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD -RGEEQLAAMIPYGQADLLEYAPVAKENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTTFWRSLGDTTSRLDHNEPALNRSQPGDPRDTTTPAAMAGNLRRLVTGDALSPPSRA -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPETPILIAAYTQG -GTPSAAQIASAFARIGRMVAE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. SM8 TaxID=1195457 RepID=UPI000283062A ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YR519 TaxID=1500259 RepID=UPI0005682D1F ---DIDKRMGELEKQIGGRIGVSAIDTETNISF-GYRETESFALCSTFKVLAAGFVLSRVD -AGKENLERRVVYDKDKLITYSPETELHVGDEMSVGELCKAAITLSDNTAGNLLLESFGGP -KELTNWLRTIGDGSTRLDRWEPDLNEAKAGDPKDTTTPDAMLDTLGNITLGSVLTEPSQQ -KLAEWMVASTTGGARLRAGLPDSWKIGDKTGTGRNGSAADIAIIWPTGRGPILVTTYVAE -AKVPVAEINPVFAEVGKIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Salmonella enterica I TaxID=59201 RepID=I1W5J4_SALET ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMLSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRGEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTDG -ES--------------------- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces jeddahensis TaxID=1716141 RepID=A0A177HLI8_9ACTN -----DGAFAELERTFDARLGVYAVDTGTGREV-AYRDRERFAYASTFKALAAGAVLRTYS ---LDGLDKVIKYSRKDLVDYSPVTERHVDTGMTVRALCEAALHYSDNTAGNLLLGMLGGP -KGLDAMLEGMGDDITRMQRRETQLNQWAPGSTPDTTTPRAFAGDLRAFVLGDVLGKAERT -QMADWLKANTTGAKLIRAGLPDDWVVGDKTGAGGFGTRNDIAVVWRPKAAPIVIAIMTNR -HTKDADYDNALIAKAASVVAR-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax TaxID=12916 RepID=A0A2T6JEP1_9BURK -----KDTLAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMRQTMQKLVLGNALSPTSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR -SMASPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. LCT2 TaxID=2493093 RepID=UPI001373C1CB -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAVIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNKSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG -GSPTAPQIEAVFARIGRMVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. 11515TR TaxID=2028343 RepID=A0A248WC62_9RHIZ -----ETQLAALESRHPGRICVSILDMGSGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKGDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDVLTAASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGAGNANDIAVLWPASRAPIIVTAYCEI -PEITADERNAVIAEIGRIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 74 TaxID=1827608 RepID=UPI000EABEE05 ---DTRARLRELEARHGARIGAFAYNLRTETTV-RHRAAERFPGCSVFKTLAAAAVLRDLD -QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP -TTITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MJM8645 TaxID=1120523 RepID=UPI0007AFCE6E ---TTSASFKGLEQQFGARLGVYAVDTGSGREI-SYRSDERFAFASTIKSLAAGALLRKAS ---DAELDKVVAYRQEDVLSWAPITSQHVATGMKVRDLAAAAIQYSDNTAANLVMAELGGP -AAVQQSLRDLGDQTTSVDRNEPTLNEATPGDTRDTSTPSAFAADLRRYALGDVLAEDRRR -LLTDWLVGNTTGAPYIRAGVPTDWKVGDKTGNGGYGTRNDAAVAWPSGGSPVVIVVLSDR -GKADATSDDALIAQATKTVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. YK2 TaxID=1860096 RepID=UPI0009F4972E -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLIDYSPATKPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSIGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRFLFTDILTAASRS -QLAAWLIANKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKRAPIIVTAYCEI -PTIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus siamensis TaxID=480071 RepID=UPI0009865DD2 -----HKDFDKLEKKYDADLGVYAIDTGTGETV-TYQANERFAYASTIKALTVGVLLQQKS ---ISDLKQRITYTRDDLVNYNPITKKHVNTGMTLNELCDAALRYSDNAAENLILKQIGGP -TGLKKALKKIGDEVTNPVYFEPKLNDVKPGETHDTSTPKALAISLKKFTLGDVLPTKERQ -LLTNWMKKNTTGDTLIRAGVPSQWEVADKTGSSDYGIQNDIGIIWPPKGEPIVLAILSHR -DEKDAASNDKLIAQATKKVINAf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229RVV1_9PSEU ---SAQADFEQLERAFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP ---VADLDRTVTYSQKDLVSNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPELNDTFPGDKRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDIMRANTTGDENIRAGVP-GWPVADKTGTAGYGTRNDIGVVWPPNRAPIVIAVLTDR -ADKDAKIDNKLLAQATAAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003A236B9 ---DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRDIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNTWLRGNTTGAELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEATEVVIA-- ->[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=G2NGN1_STREK ----TAGAFEELEDKYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYT ---VGGTDRLITYSGDDVVPDSPVAEKHVDTGMTLDALCDAAVRYSDNTAANLLLGQLGGP -EALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA -RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGTGGYGVRNDIAVLWPPDRAPVVVAVMTSR -DREDDTHDNRLLAEAASVVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD5832A ---DIDKRMGELEKQIGGRIGVSAIDTETNISF-GYRETESFALCSTFKVLAAGFVLSRVD -AGKENLERRVVYDKDKLITYSPETELHVGDEMSVGELCKAAITLSDNTAGNLLLESFGGP -KELTNWLRTIGDGSTRLDRWEPDLNEAKAGDPKDTTTPDAMLDTLGNIALGSVLTEPSQQ -KLAEWMVASTTGGARLRAGLPDSWKIGDKTGTGRNGSAADIAIIWPTGRGPILVTTYVAE -AKVPVAEINPVFAEVGKIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amphibacillus jilinensis TaxID=1216008 RepID=UPI000310B3E9 ---TVEETFSQLEEEYDARLGVYALDTGTGKTV-TYRSDERFIYASTHKPLSVGVLLQQKS ---IEDLDERITYSSEDLVNYNPITENHIDSGLTLKELSDASIRYSDNTAANLIFHEIGGP -EGFKEGLRAIGDNVTEPERIEPELNDVEPGDIQDTSTPEALAKSLQQFTLGDALPDDKQA -LLIDWLKRNTTGDALIRAGVPEGWEVGDKTGSGSYGTRNDIGIIWPPDRDPIILSVLTSK -EERDAEHDDALIARATEEVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sp. CFH 90083 TaxID=2592336 RepID=UPI00128DDE60 ---QSEEAFKALEEEFDARLGVYAIDTGSEQTV-TYRSDERFAYASTFKALAAGAILQTKS ---MEELEEVITYSEEELVAHSPVTEKHVDSGMTWKEICEAAVRYSDNTAANLMLEELGGP -DGMEEILRENGDETIEMDRMETELNEAVPGDTRDTSTPQALAESLQTYVLSDLLPEDKRE -VLMDWITGNKTGDTLIRAGVPEDWEVGDKSGAGGYGTRNDIAVVWPSDNAPIVIAILSSR -DTADADYHDVLIERAAEQVIEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. S-93 TaxID=2653122 RepID=UPI0012608BB7 -----EAQLATLESKHPGRICVSILDTASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRVHYRTSDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -KAMTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDALTPASRS -QLAAWLITNKTGDARLRAGLPKGWLVGDKTGTNGAGNANDIAVLWPANRAPIIVTAYCEI -PEIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. A134 TaxID=2681970 RepID=UPI0012EDCA4C ----TDEVFTQLENEFDARIGVYAIDTGSNQTI-EYRPDERFAFASTYKALAAAILLQQNS ---LEELKEVITYTEDDLVTYSPITEKHVDTGITLLELSEAAVRFSDNTAGNLLFEALGGP -KGFEQALREIGDHVTKADRFEPDLNNYTPEDTRDTSTPRALATSFQAFAVGDLLSDNKHE -LFTDWLKGNATGDTLIRAGAPEGWEVGDKSGAAGYGTRNDIAIVWSPNREPIVIAILSRH -NTEDAEYDDTLISQAAEIALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. SYSU K10002 TaxID=2144174 RepID=UPI000D697FFF ------SAFAELESKAGARLGVYAVDTGDGRVV-AYREGERFPMASTFKGLACGALLRDHP -LSSGFFDQVIHYTASEIVDASPETSKHVDTGMTVAALCEAAITLSDNTAGNQLLKLLGGP -EGFTAFLRSIGDTTSRLDRWETELNTAIPGDDRDTTTAAALTADYRALVVGDVLAAPERE -RLTSWLIANTTGGKRIRAGLPAEWRVGDKTGSPAYGSALDVAVTWPPGRAPLVITVLTTK -SEQQATADNALVAEATRVTL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces davaonensis TaxID=348043 RepID=UPI000996BB69 -----TARLRALEEEHGGRLGVYAHNLATRRTV-RHRADELFPMCSLFKTLAAAAVLRDLD -RDGEVLNSRLHYTEADLVDVPDVIREHLSDGMTVAALAELAITHSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRVTDTTSPAAIGRTYGRLVLGDALNRRDRE -QLTEWLLRNTTSTARFRAGLPPAWTLGDKTGSGSYGTANDVGVAWTETGAPIVLSVLTTK -PEQNAAWDNALVAKTAKVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. 106 TaxID=2135637 RepID=UPI000EB4302E --qQWQQALAQIEQKAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD -QGKERLDARVQYPASEVVDYSPVSGPKAGAGLTVGELCSATVSLSDNTAANLLLARQGGP -SALTAYLRTLGDTATRLDRNEPTLNEAAVGDPRDTTTPQAMLQTMQKLVLGDALTPASRA -TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ -SKAKPEQREAAIAEVARSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas hyacinthi TaxID=56455 RepID=A0A2S7ET11_9XANT ---TLAQRLAGIERRTAGRLGVTLLD-GNGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELRLQQPVQIRAADMLPHAPVTARHVGGALSVAELCRATMIFSDNPAANLLFPLVGDP -PGLTRFLRGLGDTQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRALLLGDALRPASRQ -RLTAWMLDNRTGDACLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLSAYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia thailandica TaxID=257275 RepID=UPI0006939340 --------FARLETEHGARLGVFAVDTGSGRTV-AYRPDERFPIASTFKGLACGALLDEHP -LSSGWFDQRITYGADELVANSPVTAQHVDTGMTVAELCHAAITASDNTAGNQILELLGGP -AGFTARLRTLGDQVTRLDRWETELNTAIPGDDRDTTTAAALAADYRALAVGDALAEPERA -QLNSWLLASTTGAARIKAGLPADWRVGDKTGTPAYGSALDVAVAWPPGRAPLVIAVLTTK -PQADAEPDNALVAAAARE----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces koyangensis TaxID=188770 RepID=A0A385DJT4_9ACTN -------ALRTLERKYDARLGVYALDTGTGKTI-GHRADERFAFCSTFKTLAVAALLDRNP ---PGHLDERVTYTRGDINSISPVTRENVDKGMTVGQLCDAAIRYSDGTAANLLLRDLGGP -ERLTDYLRELGDTVSRLDHYEPELHQVRPGDPADTTTPRAIAADYRTVILGDTLARDQRA -LLTDLLERNKTGGNRIRAGVPKGWRVADKTGTGQYGRANDIAIVWPPASGPLVLAIMSER -SGREARPSEPLIAEATEHVT--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. 106 TaxID=2135637 RepID=A0A497VCE0_9BURK --qQWQQALAQIEQKAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD -QGKERLDARVQYPASEVVDYSPVSGPKAGAGLTVGELCSATVSLSDNTAANLLLARQGGP -SALTAYLRTLGDTATRLDRNEPTLNEAAVGDPRDTTTPQAMLQTMQKLVLGDALTPASRA -TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ -SKAKPEQREAAIAEVARSAL--- ->[subseq from] Beta-lactamase n=2 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T2H2_9PSEU ---QFHDRLLELENKFDARLGVYALDTEGGGTV-EHRADERFAFCSTFKGVAAAAVLQRNP ---LSHLETRVSYSRADLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRIEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTADKRD -FLRDLLQRTVTGAGRIRAGLPHGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -AAKDAPYDEALLAEAARYVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces pseudogriseolus TaxID=36817 RepID=UPI000A3C5D47 -------RLRALEREFGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERVSYSTADLVTYSPVTEKHTADGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP -GGLTAYARRLGDRVTRLDHVEPELNSNPPGDPRDTTSPRAIAADYRALVLGDALPAAGRA -LITDWLVRNTTGDRRIRAAVPRGWRVGDKTGGGEWGRGNDVAVLWPGGRPPLVLSVLTER -TDRAASPSDELVAEAARRVLD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D91A24 -----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMGGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -SAISNEQRAQVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora azatica TaxID=58347 RepID=UPI00055B9813 -----TGRLRALEQAHSARLGVFACNTVTGRTV-LHRADELFPMCSTFKTIAAAAVLRDLD -RDGEFLATRIRYTQQEVTRYAPITGQNLAGGMTVADLCAAAIEHSDNTAANLLLRELGGP -GAVTRFCRSIADDVTRLDRWEPELNSAEPERVTDTSSPRALARTCARLTLGTALEPRDRE -RLTGWLLANTTGGNRLRAGLPNGWTVADKTGTGGYGTTNDVGIAWPPDHGPIVIAILATT -QHAATPADEPLLAATAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bicolor TaxID=66874 RepID=UPI0004E0C879 -haTTTDRLHDLEQRHGARLGVFAHNLATGRTV-RHRADERFPICSLFKTLAAAAVLRDLD -RDGEVLAKRIHYTQDDLVANSDETAKHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAVTRFARSLGDPVTRLDRWETDLNSAEPWRVTDTTSPRAIARTYARLVLFDALNRPDRD -LLTHWLLNNTTSANRFRAGLPKTWTVADKTGGGSYGANNDVGIAWTEDGTPLVLAVQTTR -PDQDAALDHALIVETAALIA--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7E2G5_9ACTN ---EVAAAFKKLERKYDARLGVHAVDTGSNQEI-SYHADERFAYASTHKAFTAAAILDKHS ---LSGLDKVITYKKKDLLPHSPVTSKHVDEGMTLRALCAATVRYSDNAADNLLLRELGGP -KALDAFLEDLGDDVTHANRYEQELNEATPGDKRDTTTPRAFAEDLRAVALGDALDKKERA -QLSTWMRESPTGKTLINAGFPKDWTVADKSGAGRYASRNDIAVVRPPGKAPLVVTVMSKR -SEQDADYDDKLVSEAASVVADE- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000DAD0900 ----TAGAFEKLEDKYDARLGVYALDTGTGREV-THRADERFAYVSTFKALLAGAVLRTYT ---VGGTDRLITYSGDDVVPDSPVAEKHVDTGMTLDALCDAAVRYSDNTAANLLLGQLGGP -EALNALLKRLGDDVTRMERLEPDLSRWDPDSTRDTSTPRAFAENLRAFVLGDVLGDAERA -RLTHWLRTNTTGDEVIRAGVPKGWTVGDKTGTGGYGVRNDIAVLWPPDRAPVVVAVMTSR -DREDDTHDNRLLAEAASVVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. EL143 TaxID=2073157 RepID=UPI000CF0CEBB ----VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGDERFPMNSTFKAFLCAALLDAAS -NGTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP -EGVTAYLRGIGDDISRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDETLAADARA -KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ -TTAAFEARNKAIAGIAQAL---- ->[subseq from] Beta-lactamase n=1 Tax=Roseovarius tolerans TaxID=74031 RepID=A0A1H8DDN4_9RHOB --dDLRQTVQDVEARIGGRIGYAVTDLNGGQEW-GSRPDERFPMSSTFKALLCGVILARVD -AGAEALDRRITFGRDDLVTYSPVTDWHLGTGMTVGELCHAAITMSDNTAGNLLLATIGGP -EGFTEILRDMGDATTRLDRWETALNEGAPGDERHTTTPRAALSTLQALLFGDMLTVASRE -QLSDWMIADAVADDLLRASLPEGWIIGDKSGAGGHGSRSIIAVVWPTPNHPVLVTIFMTG -ADAGMTDRNAAIAEIGAAIFA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000477609B ---DLSHEFRQLEERFDARLGIYAVDTGAGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLRHLGGP -ERFEQELKGIGDNVTDAARYETELNEAAPGDPRDTSTARALAEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEKDASHDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0004C57668 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDRRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAVDLRAFVLGGALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. b94 TaxID=1827634 RepID=UPI000D1A55E1 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDRRVAYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDHVTRMDRVEPKLSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces resistomycificus TaxID=67356 RepID=A0A0L8LJZ6_9ACTN ---ATARAFRDLEGEFDARLGVYALDTGTGRTV-AHQADERFAYASTFKALAAGAVLRKFG ---TDGIDKVVTYARDDLVENSPVTDDFVETGMSLRELCAATLWYSDNTAVNLLLHELGGP -DGLEKVLEQLGDHVTEMDRYEPEMSDGTPGDSRDTSTPRAMAAGLRAFLLGDALGREERD -LLRQWMETNTTGETLVRAGLPADWKVADKSGSAGYGGRNDIAVVWPDDGNPIVMAVMSSR -DKQGAERRDALIAKAATVAID-- ->[subseq from] Beta-lactamase n=2 Tax=Desulfovibrio sp. X2 TaxID=941449 RepID=S7TJZ6_9DELT ---RLAEAVQNEEAALHARIGMAVSDTNGGDVW-QYRGDERFPLNSTHKVFACAALLARVD -AGVLAPDRRVSITESMLVVYSPITKKHLAPEMTLSEVCRASVSYSDNTAGNVVVDAAGGP -AAVTAFMRSIGDGVTRLDRAEPELNEAAPGDPRDTTTPAAAAASLARVVLGDALAPSSRA -ALTDWMLHDQVADGLLRAALPPDWRIADKTGSGGHGSRSILAVVWPPKRSPLVVAIYITQ -TEASVQDANLAIARIGRVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5126 TaxID=1463857 RepID=UPI0004C57A4D ---ALDRKLAALEKRYHAHVGLYVLDTKTGRTV-SYHADRRFAHCSTIKALAAGVLLKRTS ---DARLDHVITYRKADLVSYSPITSKHVAHGMTLRAVITAALEYSDNTAENLMLAQLGGP -ESLESALRKMGDATTNADRTEPSLNDATPGDTRDTSTPRALGTDLRAFLLGDALPAGRRS -MLRNWMVHNTTGTDYIRAGVPAGWKVGDKTGSGGYGTRNDIAIAWPPARGPVVISVLTDR -GTANAPSGDALIADATRTAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=UPI0010085999 ----TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLAGAVLAKKT ---LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGTALPAEKRA -VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR -DIKNAETDDALIAGAAKVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas nepalensis TaxID=1854500 RepID=A0A502FRP4_9PROT -----EAAVRAAEREAGGRLGVAVLDTGTGARA-AWRGGERFPVASTFKLLLAAAVLQRVE -AGREGLDRRVPIAAADLVDHAPVTGRRVGPEMSVRELLEATMVWSDNPAANLLLPSVGGP -EGLTRAARGWGDEGFRLDRWETALGEGRPGDPRDTTTPAAMLLSLERLLVGEVLSGPMRD -LLVGWMVGSRTGDAKIRAGLPPGWACGDKTGAAGHGTSNDVAVVWPPGRAPVLVAAYLTE -SPAAPAGRDAALAAVGRAVAAGf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1331.2 TaxID=1938835 RepID=A0A285QAY0_9ACTN ---DTHRRLSALEQQHGARLGVFARNLSTGRTV-RYRAGELFPICSVFKTVAVAAVLRDLD -RDGEFLAKRIHYTEADIKRGAPVTGENLANGMTVAELCKAAIDHSDNTAGNLLLRELGGP -TAVTDFCRSIGDHVTRLDRWEPELNTAEPDRTTDTTSPQAIARTYRRLTLGHALPPAKRD -QLTTWLRGNTTSIHRFREGLPQDWALADKTGSGQYGTANDVGIAWTPSGAPVVLAVLTTK -PDEAAPKDEPLVAETAALLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB43_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPSLLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobiales bacterium 35-68-8 TaxID=1970552 RepID=A0A258M2C0_9RHIZ ---------GPLEAKTGGRLGICVLDGAGGIIA-AHRAQERFAMCSTFKLLLAAAVLARVD -EGRERLDRRITYTAADPVGHSPVTRQNVADGMTVGELCAATVALSDNGAANLLLATLGGP -EGLTAFLRRTGDTVTRLDRWELALNSAIPGDPRDTSTPAAMAGSIRRLVAGTVLKPASRT -QLRDWLVATKTGDTRLRAGLP-GWHVGDKTGTGNNGTVNDVGFALAPGADPIVIAVFLTK -SRLDVEASSAIIADVARQVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium forestalis TaxID=1419263 RepID=A0A2M8QY19_9BRAD -------ELETCERNSGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAATIAYDKADLLDYTPVAKQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMANNLRRLVLGEALSAQSRV -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPTAEQIAAAFARIGRIVAD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D2KB72_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALXGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pigmentiphaga sp. D-2 TaxID=1002116 RepID=UPI00104419F4 ---AALDELARLERLAQGRLGVSVVDTATGEEF-GRRADERFQMLSTFKLLAASFVLARHD -RGEDSLDRRIRYERDDLVRWSPVTEKHVGGHMSLAELCHATLTTSDNTAANLILRSFGGP -EALTRFIRSLGDNVTRCDRYEPELNVPHATGLLDTTTPHAITRTMGKLTVGEALSPASRE -RLQSWLVGNTTGDKRLRAGVPAGWRIGEKTGTYSKVGANDIGLAWPPGRPAILMSVYVAS -TRAADEVKDQVIAKVAELVG--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces cattleya (strain ATCC 35852 / DSM 46488 / JCM 4925 / NBRC 14057 / NRRL 8057) TaxID=1003195 RepID=F8JTX3_STREN ------AKFAALERKYAARLGVYAVATGTGTTV-TYRADERFAFCSTFKTLAAAAVLHRNP ---LSYLDKRVTIHAADVNSISPVTEDRVDTGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -AGLTAYLRGLGDTVSRMDHYEPELNRNPPRDPRDTTTPEALAGDYRALVLGNALPAEKRA -LLKGWLQHNTTGAERIRAALPAGWTVADKTGTGDYGRANDVAIAWPPHTAPVVVAVMTER -SGYHTPAEDPLLADATRQIL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A0642 TaxID=2563100 RepID=A0A4S2USQ2_9ACTN -----ERAFVELERKSDARLGVYALDTVSGRAV-AHRSDERFAYASTCKALLAGAVLGRNS ---LRQMDRLVRYGRDDLVTNSPVTEQHLATGLTLRELCDAAVRYSDNAAANLLFRELGGP -RALQAALRAQGDRTTRCDRYETALSDAVPGDVRDTSTPRALAGDLRAYVLGTALPADKRA -VLTDWLKRNTTGDHTIRAGTPDGWQVADKTGTGGYGTRNDIAVVWPPHATPVVLAVLSRR -DAEDAEHDDALIAHAAEIAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SM11 TaxID=565557 RepID=UPI000CD5A4E5 ------RAFVALEKEYAARLGVYAVDTGTGRAI-AHRDGERFAYASTFKALAAGAVLREYG ---LGGLERVVAYRREDLVEHSPVTEKHVATGMSLGDLCDAAVRHSDNTAGNLLFDAVGGP -RKLQAVLAELGDDVTRMVRRETELNEWSPGAVRDTSTPRAMAEDLRAFVLGDALGKPERA -RLTQWLRNNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPGAAPLVLAVLSNR -TEADAAFDNTLLARAASAAVS-- ->[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=unclassified Shinella TaxID=2643062 RepID=UPI0006816CCF --eDLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILARVD -RGEETLDRRIVVKKADLVDWSPVVETRVGGKISIAELCEATITFSDNAAANLLLAASGGP -EAVTAFLRGLGDAVTRLDRTEPTLNYETPDDVRDTTTPTAMVETLRRLVFADVLSARSKA -QLAAWLVMNKTGDARLRAGFPADWIAGDKTGTNGAGNANDVAIAWSPDRGAIIVAAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia grenadensis TaxID=931537 RepID=UPI0007A484B0 ---VTTQQFADLEAAHGARLGVFAVDTADGRSV-AYRDGERFPMASTFKGLACGALLHEHP -LSSGFFDRVIRYPRTDLVANSPVTEQHVDTGMTVAALCDAAITVSDNTAGNQILKLLDGP -AGFTAFLRTLGDDTSRLDRWETELNTAIPGDERDTTTAAALAADYRALVVGDTLAEPERA -QLAAWLVASATGGNRIRAGLPADWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK -SEQDAEPANDLVAAATRAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003782202 ---DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DAPDASYDNALIAEATEVVIA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106H9I1_9BURK ----ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAKTf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. BK707 TaxID=2512160 RepID=A0A4Q7U3B3_9BRAD -------ELESYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGDEQLAAMISYGQADLLSYAPVAKENLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSPASRT -QLTGWMVNCKTGANRLRGGLPAEWTIGDKTGNNGKDASGDIAVVWPKPDTPVVIAAYTQG -GTPTAAQIAAVFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia carnea TaxID=37328 RepID=UPI0002F54A9A ------AAFTDLETTHGARLGVFALDTGTGRSV-GHRMDERFPMASTFKGLACGGLLDRHR -LSSGFFDQVIHYPRHELVEYSPVTEQHVDTGMTVADLCHAAITVSDNTAGNQILKLLDGP -AGFTAFLRSLGDSTSRLDRWETELNTAIPGDERDTTTPAALAAGYRALVVGDRLPEPERE -QLRSWLVATTSGADRIRAGLPADWTVGHKTGTPAYGSALDVAVAWPPGRAPLVIAVLSTK -PEQDAEPDGALLAAATRIALS-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis halophila TaxID=141692 RepID=UPI00034D6A85 ------AGFERLEEEFGARLGVYALDTGSGEEV-AYNADERFAYASTFKVPACGAVMEEHS --LKEMEETVVHFDEEDLVTYSPITEDHVDTGMTLMEVCDAALRYSDNTAANLLLEEIGGP -EGFQEAMRELGDEVTVSSRWETELNENKPGDERDTSSPRAFAGNLEEYVLGDTLEEDKSE -ALADMMVRSTTGDTLIRAGVPEDWKVGDKSGMPGYGARNDIAVMWPPEGDPIVLAVYSTK -DTEDAESEDELIAQAAEEAV--- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium AO1-B TaxID=1905358 RepID=A0A1L9QJ15_9PROT ----LSKAAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACAALLDRVD -KKQSSLDQRTIITSDMIVSYSPVTEKHINTAMTLADHCEATITISDNTSANIILEELGGP -IGVTTYMRSIGDDVTRLDRYEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK -HLMQWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE -NEAEFQARNKAIAEIGAAFK--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=A0A2U8QJF4_9BRAD -------ELETYERESGGRIGVYAENLATGKKL-TWRADERFVMCSTFKASLAACVLARVD -RGEEKLAATIAYGKADLLEYAPVAKQKLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPASRA -LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILMAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0005128BD7 --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE -QKKLNLNATTTVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLYQIGGP -EQVTQFIRSLDDKVTRLDRYEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ -TQLDMAQRNHVINRVANLVFEQf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI13_KLEOX ---AIQQKLADLEKHSGGRLGVALINTADDSQT-LYRGDERFAMCSTGKVMAAAAVLKQSE -SNPEVVNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYL-- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A244 TaxID=2137016 RepID=A0A2T4NGW6_9ACTN -----TARLRELEREHTARLGVYARNVRTGRTV-TYRADELFPMASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQAYVIRFSPVTKDYVAAGMTIAELCDATIRFSDNTAGNLLLKELGGP -TAITRFARSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGGVLEPRDRA -RLTDWLLRNTTSLERFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAGAAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus kozodoii TaxID=351676 RepID=A0A2D0LF04_9GAMM ----IIHQLAILEKNANGRLGVVLIDTSDHSTL-SYRANERFPLCSTSKLMAVSAILKKSE -TNAHLLNQRVHYQQSDLVEYSPITEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGP -NEVTLFARTLGDNSFRLDRYEPELNTAIPGDERDTSTPQAMAESLYDLVLGDALATAQRE -QLAKWIKGNTTGSASISAGVPQDWVVGDKTGRCDYGTTNDIAVIWPPKRAPLVLVTYFTQ -PDKEASARPDVLAAAARIVTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Arenimonas composti TR7-09 = DSM 18010 TaxID=1121013 RepID=A0A091BCP3_9GAMM -----ANRIADLEERHGGRLGVAVLDTATGEGF-AWRAYERFPMCSTFKWLLAAQVLAAVD -AGEASLDRRLHWRREDLISGSPVVGKDPAAGLTVGELCAAAITTSDNTAANRLLAEFGGP -SGLTAWLRATGDESTRLDRNEPTLNLWRPGELRDTTTPMAMADSLRRILTGDVLSAASRA -QLIGWLLANTTGDSRLRAGLS-GWRVGDKTGTGNDGTSNDVAIAWPPDAAPILIAAYYCE -GGDDAAKRDAVLAEVGAIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium segetis TaxID=2488750 RepID=UPI0010514C19 -----RQSLRLIEDRLGGRLGVAVRDTGSGRAL-LHQADARFPLCSTFKVLAAAAILARVD -AGRERLERTMSYTAADLDSHAPATEAGRDSGMSLADLCAAAIVVSDNTAANLMLQALGGP -PALTAWLRGIGDGTTRLDRTEPTLNTAIPGDPRDTTSPAAMAEDLERLLIGDVLSPASRA -RLEGWMVAARTGLKRLRAGLPPDWAVGDKTGSGDNATANVVAILRPPHRAPLVAAIYLTG -SVSTAEERDAAHAEVGRLLAATf ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura echinospora TaxID=1992 RepID=A0A1H5T212_9ACTN ---EARRRLRELEDSYQGRIGAFAFDTGSGRIL-AHRAHERFPMLSTFKAVAAAAVLHKAR -RDPGLMDRIVRWSSEDLVDYSPITEQHVDTGLTVAQLCDAAIRYSDNTAGNLLLKQIGGP -PGLTRFLRSLGDPVSRLDRWETELNEWSAGERRDTTTPEAMGRDLHRLTVGNGLAEADRR -RLIGWLRGNTTGDKRIRAGLPEDWTVGDKTGTAGS-AANDVAIAWPPGSAPVIFAVYTAR -RDFDAPGDEQVIATTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia inohanensis TaxID=209246 RepID=UPI000A029155 ---AAESAMKGLEEKYGARLGVFAVDTKSGKEV-AYRSDERFAMASTFKGLACGALLKTYP -LSTGYFDQVIRFGREELVTYSPVTEQHVDSGMTVAELCQAAITMSDNTAGNLILRLQGGP -GEFTAFLRTLDDSVSRLDRWETELNANTPGDERDTTTPAAVAADYEKLVLGDTLGEPERE -LLKGWLIANTTGGQRIRAGVPQGWTVGDKTGAPEYGGNNDVAVAWTDKGVPVVIALLSTK -SAPDAKADNALLAEATRAVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=UPI000DDB07D1 ----LADLAADLERRIGGRLGVAHFVPRTGMLH-GHRLEQRFPMCSTFKLLAVAAILARVD -GRRDHLDARVAVREADLVAHAPVTGPHIGGTMTLADLCAAAMRESDNVAANLLLRRLGGP -AGITAYAQSLGDRATRLDRWEPDLNSALPGDPRDTTTPAAMARLAGRILEGDSLRPPSRA -LLRRWMTQTRTGLTRIRAGLPHSWSVGDKTGSGANGTANDVAWFHPPGRDPAILAIFLTD -TQASAAARDAVFATIARHVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces ossamyceticus TaxID=249581 RepID=A0A3N1LJD7_9ACTN --------LRALEEQYGARLGVYAHNVRTGETV-RHRADTLFPICSLFKTLAAAAVLRDLD -RDGEVLSRRIHYTAADLLENSDVTRDHLATGMTIAELCDAAIRHSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRPDRA -LLTHWLLHNQTSNTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSIVSRK -FDRDAATDNKLIADTAHLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003FAF381 ----LNHEFRQLEERFDARLGIYAVDTVTGRTV-RYRADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLHHLGGP -ERFEQELRGIGDNVTDADRYETDLNEATPGDPRDTSTARVLAEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEATEVVIA-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Shinella TaxID=2643062 RepID=A0A4Y8QIP1_9RHIZ ---ALGKRLAELEARHKGRIGVAIHNLATGARL-GHRADERFLMCSTFKALLAGHILARVD -RGEETLDRRIVVKTSDLVDWSPVVEKHVGDAISVAALCEATITLSDNAAANLLLAVSGGP -EAVTAFLRGFGDTVTRLDRTEPTLNYDSPADERDTTTPAAMTDTLHRLVLGDVLSPQAKA -QLAAWLVMNKTGDTRLRAGFPANWMTGDKTGTNGAGNANDVAIAWSPDRGAIVVTAFVEM -PGISGDDRNAIIAEIGRVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00039FB764 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDHAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=2 Tax=Oceanobacillus picturae TaxID=171693 RepID=A0A0U9H5G1_9BACI ---KLDEEFASLEDDFDAQLSVYALDTGADQTI-AYRAEERFAFSSTYKALAAALLLEQNE ---MEELNEVITYTEDDLVPYSPVTEKHVDSGMTLLEIGEAAVRTSDNTAGNLLFEALGGP -AKFEEALREIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLTDEKRE -LFTDWLQGNATGDTLIRAGAPKGWVVSDKSGAGTYGTRNDIAVVWPPDREPIVMAIMSRH -DTEDADYDDALISEAAEVVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces violaceoruber TaxID=1935 RepID=UPI0004C6B5F6 ------GAFRQLEREFDARLGVYALDTGTGRSV-AYQADERFAYASTFKALAVGALLQRRG ---QAGLDKVLTYSQDDLVENSPVSENFVGTGMSLRELCAATLWYSDNTAANLLLEELGGP -DGLEKALERLGDDVTEMDRYEPDLSDGTPGDLRDTSTPRAIAGDLRAFLLGKALERDERA -LLRTWMETNTTGETLIRAGLPDDWTVADKSGSAGYGGRNDVAVVWPDDGDPVVLAVMSSR -DTQGAERRDALIAKAATVAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces decoyicus TaxID=249567 RepID=A0A0L8LU52_9ACTN ------EALRRLEHTHRARVGAFAHNTATGATV-AYRAHTRVPLCSVFKPLAVAAVLRDLD -RNGETLARRIHYTDADLVENSPVTEKHVATGMTIAELCAAAVRRSDNTAGNLLLRELGGP -TAVTAFARSLGDRTTRLDRWETELNSAEPWRRTDTTSPAAIGRTYARLLVGDALSASDRG -RLTAWMKTNETNTERFRAALGKAWAIADKTGSGSYGTGNDVGVAWAPDGTPIVLAVLTGK -PEQAAAYDNPLIVDVTKVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L6R6_9ACTN -----ELDFALLEEEFDATLGVYALDTGSGEAV-EYRADDRFAYCSTFKVPLFGVVLEQTT ---PEELEKEVPVSEDDLVNWDPIAEQHVGGTMSLYELGNAALRHSDNAAANLLLEELGGP -EALDAALEEIGDDVINVDRIEPDLSEGAPGDERDTSTPRAMATTLEAFTLGDVLPEDESE -TIVEMMRGNTTGDDLIRAGVPDDWEVGDKTGSGGYGTRNDIAVLWPPEGDPIVLAVMSTR -GQEGAEHDDALIAQATEVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D112776 ---ETLVKVKDAEDQLGARVGYIELDLNCGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRLVVIYTT- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. PHM005 TaxID=2590016 RepID=A0A4Y6S284_9RHOB ----LQKAANEIENRLKTRIGIAVYDPENAIEW-DYNGDQRFPMNSTMKAFACATLLHQVD -TGKSDLGQPVAIEEDMIVKHSPVTKDHIGSSLTYADLCEATVTTSDNTAANLVLQELGGP -AGLTAFMRSVGDQITRLDRYEPTLNEGTPGDPRDTTTPRAAAETLYKLVFSNALSDASRN -KLAGWLEGNLVGDSTLRAGLPEGWRIGDKTGAGAYGSRGNIAIIWPPNRKPLALVVYLTE -NKAAFKVRNKAIAEVGAAFA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI00031E383A -------AVARLEEHLGARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFSQSELVAYSPVTSKFVAPSMSWQQLCSAAITESDNTAANLLAKKLGGP -AAVTRFFVDSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLTLGEVLTPRSRA -QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD -TKATIAQSNDAIARIGKAIFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. LMO-1 TaxID=2681549 RepID=UPI0012E8D4AE ----LRSRLAALEARSGGRLGVAVLDVRHGRID-GYRIGERFRMCSTFKALAAGFVLHRAD -RGEERLDRRIGYTSADLPDYSPVTEKHVASGMTMAELCHAAVTVSDNGAANLLLASFGGP -AALTAFLRRIGDRKTRLDRIEPALNSGAADDPRDTTSPAAMAATLRRLVLGDALSPASRA -RLGAWLVASTTGRTKLRAGIPAGWTVGDKTGSWGGGISNDVAILWPPGRPPMLIAAFLAA -PLVD-EARSAILADVARIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. AU4i TaxID=1335308 RepID=U2FU55_9BURK -----EMRLAQIEAQVGGRLGVAILDTASGKQV-GWRMYERFPMCSTFKILLASLVLMRTD -HGQEDLTRKIVFSKREVVPSSPVSGPRADSDMTIAELCEAALTHSDNTAGNLLLTSVGGP -TGLTAFARSIGDKFTRLDRNEPALNEAAEGDPRDSTTPAAILSDMHALLLGSTLSSSSRD -QLIAWLVSNKTGDARLRARLPKDWRIGDKTGTGDHGTVNDIAVVWPAGRAPVFVGAYLTG -ATATSTQRDEAIAKIGELVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01580 TaxID=1703933 RepID=A0A1Q5GK15_9ACTN ----VASRLAQLEREHTARLGVYAHHTRTRRTV-AYRADERFPMCSLFKTIAAAAVLRDLD -HDGEFLAERIHYTRRYAEDYCPITGENIARGMTVGALCDAAIRHSDNAAGNLLLRELGGP -TAVTRFCRSTGDGRTRLDRWEPELNSAEPWRTTDTTTPRAIGRTYANLTLGDALSPRDRR -RLTGWLLGNTTSDERFRAGLPADWTVADKTGGGRYGGSNDVGITWPPGGAPIVMAVLTTR -YEEDAQADNALVARTASLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ICC1 TaxID=2099583 RepID=A0A2Z4VBJ8_9ACTN ---AVAQRLAELERAHSARLGVHAHDTATGRTV-GYRARERFPLCSVFKTLAVAAVLRDLD -RDGEFLAKRIRYTGQEVTGHTPITGKNLADGMTVGELSDAAIRFSDNAAANLLLRELGGP -TAVTRFARSIGDATTRLDRWEPELNTAEPWRITDTTTPHAIGRTYERLTLGTTLAPADRR -RLTDWLLGNTTGGERLRAGLPPAWAVADKTGGGAYGTNNDVAVAWPPGRPPLVIAVLTTR -SHRDAPADNLLIARTAEVVS--- ->[subseq from] Beta-lactamase n=1 Tax=Niveispirillum cyanobacteriorum TaxID=1612173 RepID=A0A2K9NK95_9PROT ----MREAMAALERARGGRLGVTLLDTKTGAAM-NWRGDERFAMCSTFKFLLAGYILSRVD -TGQERLDRLVTFGKHELVMWSPMTEPHVDKGMSIADLCQAIMIQSDNTGANVLMRESGGP -AALTAFLRATGDGVTRVDRIEPEMNVVGPGDVRDTTTPVSMLGLMRSLLLGDVLKPASRQ -LLIDWLIDNRTGKDRLRAGLPAGWRIGDKTGTYE-AFNNDIAILWPPAGGPLLLTSYYAN -PTADKAVRNIVHAEVAAIVAKAy ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia pseudosacchari TaxID=1646340 RepID=UPI000BE4E72D ----------LQEERLGARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP -AAVTRFFADSGDSVTRLDRAEPELNSAVPGDVRDTTTPLAVSHTLQKLALGSALTPASRA -QLVQWMKEDKVAGALLRSTLPKGWMIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYVTD -TKATMAQSNDAIARIGKAIFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. Root561 TaxID=1736560 RepID=UPI0006FC50A2 ---AIAARLAALERKHGGRLGVAMLDTGSGHHA-GRRIDERFLMCSTFKLLAVAAVLARVD -QGSEQLDRRIIFGKDVLLAWAPETSRHVGAPMTVGELCQAAITVSDNTAANLLLASLGGP -AAVTAFVRTLGDPLTRLDRTEPELNVGGPGELRDTTTPQAMLGDLRALLLGDALSAASRA -RLTGWLRACTTGLHKLRGGLPSGWQAGDKTGSGTQGESNDVAILWPPQRAPVLVTAYYAP -TSPDADVGARVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylovirgula sp. 4M-Z18 TaxID=2293567 RepID=A0A371WPA7_9RHIZ ---AANARLVALEQEHGGRLGVAIGESGGNLTI-AHRADELFPMCSTFKFLAAAAILKRVD -AGAEHLDRAIAYGQADLLSYAPIAKRHVAEGMALGDLCAAAIQWSDNTAANLMLRELGGP -SAITRFARDVADRVTRLDRTEPTLNTAIPGDVRDTTSPAAMQRDLDAILLDDRLSAASRA -QLETWMIGNQVAGKRLRAGLPPSWRIGDKTGTGDNGTANTIAMIRPPSGTPILATVYYTG -SSESPDVLNSVHAEIGRIIAQVf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis synnemataformans TaxID=61305 RepID=UPI000349E597 ------REFEQLEEEFDARLGVYAVDTGTGEEV-AHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEEDLVDYSPITEQHVDTGMTLTEVADAAVRHSDNTAANLLFEELGGP -DSFEDELEEIGDDVTDAERIETELNDWTPGDTSDTSTPRAMTESLREFTIGDALPEDRRE -VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAGSHGTRNDIAVLWPPEGDPIVLAVMSSR -EAEDAEYDNALIARAAEIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000486158F ---DLNHEFRQLEESFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLKHLGGP -ERFEQELKGIGDNVTDAARYETELNEAIPGDPRDTSTARALTEDLREYAVDDALEPTDRD -LLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. NFACC38-1 TaxID=1566268 RepID=A0A1I0LUH6_9BURK -----EMRLAQIEAQVGGRLGVAILDTASGKQV-GWRMYERFPMCSTFKILLASLVLMRTD -HGQEDLTRKIVFSKREVVPSSPISGPRADSDMTIAELCEAALTHSDNTAGNLLLTSVGGP -TGLTAFARSIGDKFTRLDRNEPALNEAAEGDPRDSTTPAAILSDMHALLLGSTLSSSSRD -QLIAWLVSNKTGDARLRARLPKDWRIGDKTGTGDHGTVNDIAVVWPAGRAPVFVGAYLTG -ATATSTQRDEAIAKIGELVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. ST3 TaxID=2219062 RepID=UPI000DA654E6 ---AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLEARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSPTSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR -SMASPEQRDAAIARVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. BK441 TaxID=2512175 RepID=A0A4Q7RFW7_9GAMM ---PLEAALARIEQQAGGRLGVALHDAQGRRLA-GRREDERFPMCSTFKFLLAAAILHEVD -GGRLTLDRRVPIAASDLLGNSPVTEQHVGPRLSVAELCHATVTLSDNAAANLLLPQVGGP -PGLTAFLRASGDAVTRLDRTEPTMNLFAPGDDRDTTTPAAMAGNLRRLLLGDVLKPVSRA -LLVAWLRDNRTGGKRLRAGLPAGWRVGDKTGFNGEDTTNDIAILWPPGAAPLLLATYLQG -AKVDPDGQNAALAAVAAAVAR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces viridifaciens TaxID=48665 RepID=A0A1L9DG14_STRVF -------AFKDLEQHFGARLGVYAVDTGSGREV-AYRSDERFAFASTIKSLLTGALLRTAS ---DQELDKVVTYRQDEVLTWAPITSRHVDTGMKVRDLAAAALEYSDNTAANLLMTELGGP -ENLQRTLRELGDPTTNVNRNEPTLNEATPGDPRDTSTPRAFAADLRRYVLGDVLTEDRRR -MLTDWMVGNTTGAPFIRAGVPAHWKIGDKTGNGGYGTRNDVAVAWPSGGSPVVLVVMSDR -GKADATSDDALIAEATKAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A1K2D8S7_STRAR -----TGRFKELERKFDARLGVYAIDTGTGREV-THNDGERFAYASTFKALAAGAVLRKYS ---VDGLDEVITYSRDDLVSNSPVSEKHVGTGMSLGALCDAAVRFSDNTAANLLLDRLGGP -RGLDAVLAGIGDDVTRMEHGEPQLNQWSPGALSDTSTPRALAGDLRAFVLGGVLEKGERA -QLTKWLRTNATGDELIRAGMPKNWVIGDKTGSGGYGTRNDIAVVWPPDKAPIVVAILSNR -SEPDADYDNELIAQAASVVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID11233 TaxID=2706029 RepID=A0A6B3ET84_9ACTN ---RTEQAFRDLERKFDARLGVHTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLHKNS ---LRQMDRLVRYGRDDLVSASPVTERHVATGMTLRELSDAAIRYSDNTAANLLFHELGSP -RALQEALRALGDDVTRCDRYETALSDATPGDPRDTSTPRALATGLRAYVLGNTLPSDKRA -VLTDLLRRNTTGDNTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLTRR -DAKDAERDDALIAGAAKVALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia spinosispora TaxID=103441 RepID=UPI000420E0F8 ---RATAELADLEARFVGRLGVYALDTGNGATV-GHRADELFPMCSTFKVLAASAILRLRT -QQPGLLDRVVHYTQAQMVDGSPISSTHLADGMTVAAMCAAAIQYSDNSAANQLLDILGGP -RGVTAFVRTLGDPLTRLDRYETDLNIVPPGEVRDTSTPEWMGKNLRALALGDALDPAGRD -QLVEWMVGNTTGATRIRAGLPNGWRVGDKTGGGARNEINDIAVCWPPNRAPLVIAVYTAP -TDPNAKGDGKVLADAASIVVR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2Z4C2F4_KLEPN ---ETLVKVKDAEDQFGCTSGLHRTWISTARSFeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces abyssalis TaxID=933944 RepID=A0A1E7JPW6_9ACTN -----DREFEELEREFGARLGVYAVDTGSGREV-AYNDGRRFAYNSTFKALAAGEVLRRHS ---PDGMDRRITYSRDDLIANSPVTAKHVGSGMTLDELCDAAVRYSDNTAANLLFDVLGGP -EGLDAALEDIGDDVTRMERREPQLSRWTPGSTRDTSTPRALAGDLRAFVLGDVLGEAERK -QLSEWLRTNTTGDELIRAGVPQDWVVGDKTGSGSYGGRNDIAVLRPPGGAPIVVAILSHR -KERDAEFDNELIAKAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium yuanmingense TaxID=108015 RepID=UPI0012F81208 ------SEFESYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAANVLARVD -RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMVGNLRRLVTGEALSPASRT -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPSATRITSAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Shinella sp. DD12 TaxID=1410620 RepID=A0A021XGS7_9RHIZ --eDLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILARVD -RGEETLDRRIVVKKADLVDWSPVVETRVGGKISIAELCEATITFSDNAAANLLLAASGGP -EAVTAFLRGLGDAVTRLDRTEPTLNYETPDDVRDTTTPTAMVETLRRLVFADVLSARSKA -QLAAWLVMNKTGDARLRAGFPADWMTGDKTGTNGAGNANDVAIAWSPDRGAIIVAAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003FFE7EE ---DLSHEFRRLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAAVLDATT ---DAELEQVVRYSADDLVDYSPITQQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPADRD -VLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEATEVLL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia testacea TaxID=248551 RepID=UPI0002D4592C ----ATTRFADLEAAHGARLGVFAVDTADGRSV-AYRDGERFPMASTFKGLACGALLHEHP -LSSGFFDRVIRYPRTDLVENSPVTEQHVDTGMTVSALCEAAITVSDNTAGNQILKLLDGP -AGFTAFLRTLGDDTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVVGDSLAEPERA -QLSAWLVASATGGNRIRAGLPPGWKVGNKTGSPAYGSALDVAVAWPPGRAPLVIAVLTTK -SEQDAEPANDLVAAATRAAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium sp. BK315 TaxID=2512135 RepID=A0A4R3G8D3_9RHIZ -----EAQLAALESKYPGRICVSILDVASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP -GAITTFCRSIGDEITRLDRTEPTLNHATPNDERDTTTASAMLENLQRLLFTNVLTPASRS -QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI -PAIAADERNAIIAEIGRIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E2ZV53_SPHSX --------FDDLARKLDGGIGISALDTGSGRRV-DFDAISRYSLCSTFKLPLAGMILALND -AGQLALNETIAFTAADRVPYAPFIERHMDRGAAIAELCEAAVTVSDNVAANLLLRRIGGP -EAFTQWLRSIGDTTTRLDRIEPDLNSNIPGDPRDTTTPAAMLDTVHKLALGNVLTPASRA -QLAAWMVACETGDKRLRAGVPSEWRVGDKTGTSTNGASNDVAIIWPPESAPILIACFINN -DRVTAEDRDAAHAEVARRILHAf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia kruczakiae TaxID=261477 RepID=UPI0007A3DA4A -------GFRDLEARLHGRLGVYALDTGTGRAV-EYRPDERFPYCSTFKALAAGALLSTLP ---PAELDRRVTYTRADLVPNSPVTEQHVDQGMTLREIMDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRAIGDTTTRMDRTETTLNEALPGDERDTSTPRALAGDLRHYVLDPSVAADDRD -VLTGLLRANTTGAALVRAGVPVGWQVGDKTGAGDYGTRNDIAVAWPPGRAPIVLTILSTR -DRPDAEYDNAAIARAATIAI--- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter sp. R4-368 TaxID=1166130 RepID=R9VHD3_9ENTR -------AVARLEEHLGARIGIAVVDTASGEAV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALNETTQFAQSELVTWSPVTSKFVAPAMSWQQLCSAAITESDNTAANLLAKKLGGP -AAVTRFFADSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLALGEVLTPRSRA -QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGDYGSRSIISIVWPKKGAPRIVSIYITD -TKATMAQSNDAIARIGKAIFS-- ->[subseq from] Beta-lactamase n=1 Tax=Shinella sp. JR1-6 TaxID=2527671 RepID=A0A4Q8MM99_9RHIZ --eDLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILARVD -RGEETLDRRIVVKKADLVDWSPVVETRVGGKISIAELCEATITFSDNAAANLLLAASGGP -EAVTAFLRGLGDAVTRLDRTEPTLNYETPDDVRDTTTPTAMVETLRRLVFADVLSARSKA -QLAAWLVMNKTGDARLRAGFPADWMAGDKTGTNGAGNANDVAIAWSPDRGAIIVAAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=UPI0005BB7E11 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSAFKALQAGVVLGKYS ---LDGLDQRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLGEALPAPERE -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mexicanus TaxID=178566 RepID=UPI001357C54B ---DTEDRLSDLERRYGARLGIWARNTRTGHVV-AHRAGERFAMCSTFKAFAAAAILRDQD --RCAPLDRLIAYPPADLLPNSPRTEEHTGTGMTVGELRAAAIQYGDTTAGNLLLRQIGGP -AGLTRFFRSLGDPVSRLDRWEPDLNTAIPGDPRDTTTPQALGRTLERLTLGDALTGADRT -RLVDWMKGTTTSAERFRAGLPQGWVVADKTGTGDYASAHDVGVAWTTRNTPLVLTVLSSR -ATADAPVDNALIADAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces puniciscabiei TaxID=164348 RepID=A0A542SYW1_9ACTN ------AELTELERRHGARLGVYARNARTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --GCAPLDKVIHYPPYDILPNSPRTAEHVDTGMTVAELCAAAIQYSDNAAGNLLLRQIGGP -TGLTGFFRSLGDRVSRLDRWETDLGSAIPGDPRDTTTPRSLGRSFERLTLGRALADADRE -QLVTWLKGNTTSAARFRAGLPGDWVLADKTGTGDYGSGNDIGVAWTTRGTPVLLTVLSAK -PAQDAPADDALVAEAARIVA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00056E533C ---STARNFAALEAASGGRLGVTLLDTGNGQRI-GHRQDERFPMCSTFKFALCATVLRLAD -QGKLSLDRRLAMTTQDLLSHAPLTARHVGKDVTVRDLCRATMVTSDNPAANLLLRVVGGP -AGVTAFLRASGDDVTRNDRYEPDVNLFAPGDPRDTTSPAAMAASLQRLVLGERLQPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ARLDDAGRNDVLRQVAVIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0003A2E760 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-CYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKEIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWIVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASSDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FE49E -------ELETYERESGGRIGVYAENLTTGKKL-TWRADERFVMCSTFKASLAACVLARVD -RGGEKLAATIAYGKADLLEYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGEALTPASRA -LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILMAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobiaceae bacterium TaxID=2026800 RepID=A0A4Q3AQT0_9BACT ---------AKLESRHGGRLGVTTLDLGERTSF-SHRGGERFAMCSTFKFLLSAAVAARVD -AGDEQWDRKVAYGKKDLIPWTPVTGKNLKAGMTVADLCEASMTWSDNTAANLLLSSVGGP -DGLTRYLRSIGDETSRLDRTEPDLNSNVRGDERDTSTPEAMIATMEKLLFGKSLTEASKE -KLIGWLVANHTGDKRIRAAMDPAWKIGDKTGTGENGAANDIAVVWPEDRKPCLIVVFYDA -AQATAEQRDTVIADAAKLV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A482LQ94_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLPSRQ -QLIDWMEADKFAGPLLRSALPAGWFIADKSGAGERGSPGIIASLLPDGRPSRSVVIYSTG -SQ--------------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Stappia sp. TaxID=1870903 RepID=A0A2E6Y902_9RHOB ---EVADTVSRLEQRLGGRIGVVLRETGADTPVvAIRADERFPTASTFKPSLCAAVLARVE -RGEERLDRKIAYQPSDLVTYSPVTEKYAGGPLTIDALCEASVSVSDNTATNLLLTTVGGP -KGVTTFLRGIGDDTTRLDRTEPELNASIPGDPRDTTTPAAMARTLETLILGAGLAPASRK -RLETWMVNDKVADALIRKHLPPTWRIADKTGAGANGTRGIISVIWPETGTPHLAVIYMTG -SSADITTRNAAIAEIGKAMIS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces gilvosporeus TaxID=553510 RepID=A0A1V0TKQ5_9ACTN ----TEATLRDLERQYGARLGVFARNVRNGRVV-AHRAGERFAMCSTFKTFAAAAVLREHG --RCAPLDKVIHYPARDILPNSPITEQHVDTGMTVGALCAAAIRYSDNAAGNLLLRQTGGP -GGLTDFFRSIGDPVSRLDRWETDLNAAVPGDPRDTTTPQAIGRSLERVTLGRALDEAGRR -HLVTWLKGNTTSGERFRAGLPGDWIVADKTGTGDYASANDIGVAWTTEKTPIVLVVLSSK -PARDATVDNALIADAARVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinoallomurus bryophytorum TaxID=1490222 RepID=A0A543CMX2_9ACTN --------FKDLEDEYGVRLGVWALDTGTGRTV-TWRAGERFAYASTYKALAAGELLRRDP ----GGLDDVVTYTKADLVTYSPITEQHVGTGMTVRALCDAAIRYSDNTAGNLLLRRLGGP -KGLQAALRRLGDHTIHADRYETALNDAVPGDVRDTSTPRALGTDLRKYAIGNVLPKSGRG -LLDDWLRRNTTGTAMIRAGVPAGWTVGDKSGAAEYGTRNDVAVAWPPHRAPIVLAILSTK -TTQDATYDDALIAAAARVTV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Kushneria indalinina DSM 14324 TaxID=1122140 RepID=A0A3D9E047_9GAMM --qEVARRLQALEQQHKGRLGVALMNVGTGAVV-SHRGDERFLFNSTGKVFIAAAALAQVD -RGEESLDRRIEIKSSDLTGWTPVTEKQMGSPMTIAELGQAAVAWSDNAAANLLIESLGGP -AEVTAFLRGIGDTTTRLDRTEPTLNEHHDGDERDTTTPRAMMQTLRTLLLGEVLSPASRH -QLAAWMIEGKTGDARLRAGMPSGWLVGEKTGTNSVGNAGDIGIAWPSDRGAVIVIAYVYL -PEADKAQRDQVIAEIGKLAAK-- ->[subseq from] Beta-lactamase n=2 Tax=Roseovarius sp. 217 TaxID=314264 RepID=A3VZZ2_9RHOB ---RLTQTITQIEQTLDARVGLHIHDSATGWTV-THRPNERFLMASTFKAMLCGAVLSRVD -KGTLALDEPLEITEQDILEYAPITESEIGKTMSLGELCFAALDLSDNTAANLLIDRLGGP -HEVTAFLRAIGDPVSRLDRREPDLNTFTPGDPRDTTTPAAMASTLETLLAGDALSPQSRA -QLVKWMSAGGVTGALIRASTPKGWQVADKSGSGAY-NRNIVAMVTPPDQSPYVITMFLSD -ADADFATRNAAVITLSKAVMD-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00039AE6B4 ---DLNHEFRQLEESFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLKHLGGP -ERLEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -LLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter sp. TND4EH1 TaxID=1907399 RepID=UPI000C170DD6 ----AAGRLAALERKYGGRLGVSMLDTGSGQQA-GHRADERFLMCSTFKLLAVATVLGRVD -KGREQLDRRITYGKEVLLAWAPVTSRHVGADMTVGELCEAAITMSDNTAANLLLASLGGP -GVVTAFVRTLGDPLTRLDRIEPELNVGGPGDLRDTTTPAAMLGDMRALLLGDALAAVSRQ -RLIGWLRACSTGLDKLRVGLPAGWDAGDKTGSGAQGESNDVAILWPPRRAPMLVTAYYAP -ATPDKATSVRVLAEVGRITA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. Root179 TaxID=1736482 RepID=A0A0Q8LF36_9GAMM ---AIAARLAALERKHGGRLGVAMLDTGSGHHA-GRRIDERFLMCSTFKLLAVAAVLARVD -QGSEQLDRRIIFGKDVLLAWAPETSRHVGAPMTVGELCQAAITVSDNTAANLLLASLGGP -AAVTAFVRTLGDPLTRLDRTEPELNVGGPGELRDTTTPQAMLGDLRALLLGDALSAASRA -RLTGWLRACTTGLHKLRGGLPSGWQAGDKTGSGAQGESNDVAILWPPQRAPVLVTAYYAP -TSPDADVGARVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus mangrovi TaxID=1491830 RepID=UPI0012BA92BF -------GFEELEKEYQAKLGVYALNTGSSKSV-SYNADERFAYASAHKALAVGTLLKQKS ---IGELEEKIHFTEDDLVNYNPVTEKYVNEGMTLKELSDASIRYSDNTAANLIFDAIGGP -EGFKEALREIGDDVTNPERIEPDLNDVNPGETRDTSTPKALAESLQAFTLGDVLSGEKQE -LLNDWLKRNTTGDNLIRAGVPEDWVVGDKTGSGSYGTRNDIAVIWPPDDDPIILAILSSR -ENADADYDDELIAKAAKIAVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. GP55 TaxID=1798190 RepID=A0A2N3UEE5_9ACTN -----TEAFAQLEQQFGARAGLYALDTGSGREV-AYHADDRFAFASTIKSLSVGTLLRHAS ---DAELDKVVTYHQEDVLSWAPVTSKHVADGMKLRDLATAAIEQSDNTAANLVTAELGGP -AAVQQALRDLGDRTTNVNRTEPTLNEATPGDTRDTSTPRAMATDLRQYVLGDTLAGDHRQ -LLTDWLVGNTTGGPYIRAGVPTGWKVGDKTGNGGYGTRNDIGILWPNDGAPIVIAVLTDR -GKPDAKSDDALIAQATKAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=UPI000C1991C2 -----RARFTALERKYGARLGVYALDTGSGATV-SYRADERFAFCSTFKAFAAAAVVHRNP ---RSHLDKRVTYTEADVDSISPVTEDHVATGMTIRQLCDAAVRYSDGTAGNLLMRDIGGP -EQLTAYLRGLGDKVSRMDNYEPELNQVRPGDPRDTTTPEAVAADYRKLVLGDALSGDERA -LLKGWLLRNTTGKKRIRAGVPRGWKVADKTGTGNWGRANDIAVVWPPHKAPLVMAVLSDR -PGYRARPKNSLIAKATEQIV--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. 35-64-16 TaxID=1970312 RepID=A0A258NAG4_9BURK ---QWSDALAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYPVADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANLLLARHGGP -AGFTAFVRSLGDGATRLDRTEPTLNEAAGGDPRDTTTPLAMLQTMRKLVLGGALTPASRA -WLQRWMVETTTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPSGAPVLVTCYLTR -STAQPEQRDAAIAQVARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. GT TaxID=1971364 RepID=UPI0009F480E6 ---NLLTEVDRIERQLDARVGFAAYNLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGNEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP -QAVTEFVRELGDSVTRLDRWETELNEATPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN -QLREWLVNNEVADGLFRSHMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNSAIAELGSVIIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis nigrescens TaxID=381445 RepID=UPI000683D936 ---EHHDQLVELERKFGARLGVYALATGTGAAL-AYRADERFAFCSTFKGLAAAAVLRRNP ---PSHLDTVVTYTEDDLLKSAVITRQHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -AELTTYVRGLGDAVTRMDRIEPAITEATPGDPRDTSSPRALGSTYREIVLADALPAEQRA -FLRDLLERNTTGAQRIRAGVPREWTVADKTGTGDYGTANDIAVVWPPNAAPLVIAIMSSK -AAKDAEYDQTLIAEAAAYVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces klenkii TaxID=1420899 RepID=A0A3B0AZZ2_9ACTN ----AERAFGELEKRYDARLGVYAVDTGSGRSV-ANRPDERFAYASVCKAFLAAAVLKRNS ---LKQLDRLVRYSHDVPVGHSPVTTRHVDSGMTLRELCDAAVRYSDNGAANLLFDELGGP -KGLQDALAATGDRVTRADRYETDLSEGTPGDPRDTSTPRAMAAGLRAFVLGDALAPDKRS -ILTDWLKRNTTGDTLIRAGVPGGWQVADKTGSGGYGARNDVAVLWPPKAAPIVIAVFSSR -GAQDAKRDDTLIARAAEAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000418A2CC ---DLHHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELGQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLRHLGGP -ELFEQELKEIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASYDNALIAEATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000534D68D ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLQEYAVDDALDPTDRD -ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEAAEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB519C -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKKSDLIDYSPATKPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -EAITTFCRSIGDEITRLDRTEPTLNYDTPTDERDTTTASAMLENLRRFLFTDILTAASRS -QLAAWLIANKTGDTRLRAGLPKDWLVGDKTGTNGYGNANDIAVLWPSKRAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Bacteria (miscellaneous) TaxID=49928 RepID=V5SM17_9BACT ------DDFAALEAASGGRLGVTLLDTATGQRI-GHRQDERFPMCSTFKFVLSAAVLHLAD -QGTLSLDRRVLVRQQDMLSHAPVTMRHIGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGEVLKPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGKDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. HSS6-12 TaxID=2720024 RepID=UPI00143AF055 ---TWREQLRELEQGYAGRIGMYARHMGTGRTL-CYRADERFPLLSTFKVLVSAAVLDRAR -SAPGLVDRRIRWTEADLVDYSPVTEAHVADGLTVAQLCHAAITRSDNTAGNLLLRQVGGP -VGLTGYLRRLGDGVSRLDRWETDLNVWAPGERRDTTTPAAMGRDLAALTVGRALHPDDRT -TLVDWMRATVTGDRRIRAGLPAGWTVGDKTGSSNYGAANDVAVAHPPTGAPLVLAIYTRR -ETQGQPYDEAIIAETARVLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G8ENQ3_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPIMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYT-- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. TD01 TaxID=999141 RepID=F7SP12_9GAMM ---NLLTEVDRIERQLDARVGFAAYNLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGNEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP -QAVTEFVRELGDSVTRLDRWETELNEATPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN -QLREWLVNNEVADGLFRSHMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNSAIAELGSVIIE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB02_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNRFAEGDPRDTTTPAAMAGSLQRVVLGQVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLRA -GQISYEQQAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. H13 TaxID=2605988 RepID=UPI001239647F ------REFEQLEEEFDARLGVYAVDTGTGEEV-AHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEDDLVDYSPITEQHVDTGMTLTEVADAAVRHSDNTAANLLFEELGGP -DAFEDELEEIGDDVTDPERLETELNDWTPGDTSDTSTPRAMAESLREFTLGDALPEDRRE -VLNDMLVNNTTGDELIRAGVPEDWRVGDKTGAASHGTRNDIAVIWPAEGDPIVLAVMSSR -EAEDAEYDNALIARAAEVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MZ04 TaxID=2559236 RepID=A0A4R9EKR3_9ACTN ---KAASRFAALEREHDARLGVYALATSTGAVL-THRADDRFAFCSTFKTLAAAAVLDRKP ---LRHLEKVVTFSEADVDSISPVTENHVATGMTIRQLCDAAIRYSDGTAGNLLMRDIGGT -RRLTAYLRGLGDAESRMDQFEPELNDNRPGDPRDTTTPRAIARDYQELVIGKALPARKRA -LLKDWLERTTTGEKRIRAGLPKGWTLAHKTGTGNYGRANDIAVVWPPTAAPIVLAIMSDR -SGYDAEPREALIADAAAYVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7EJA0_9ACTN -----RARFTALERKYGARLGVYALDTGSGATV-SYRADERFAFCSTFKAFAAAAVVHRNP ---RSHLDKRVTYTEADVDSISPVTEDHVATGMTIRQLCDAAVRYSDGTAGNLLMRDIGGP -EQLTAYLRGLGDKVSRMDNYEPELNQVRPGDPRDTTTPEAVAADYRKLVLGDALSGDERA -LLKGWLLRNTTGKKRIRAGVPRGWKVADKTGTGNWGRANDIAVVWPPHKAPLVMAVLSDR -PGYRARPKNSLIAKATEQIV--- ->[subseq from] Beta-lactamase 1 n=1 Tax=Bacillus cereus TaxID=1396 RepID=BLAC_BACCE --qATHKEFSQLEKKFDARLGVYAIDTGTNQTI-SYRPNERFAFASTYKALAAGVLLQQNS ---IDSLNEVITYTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGIPTDWVVGDKSGAGSYGTRNDIAVVWPPNSAPIIVLISSKD -EK-EAIYNDQLIAEATKVIVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. Tu 6176 TaxID=1470557 RepID=A0A022MN91_9ACTN ---RATDALRALEERYSARLGVHARNTRTGQSV-GYRAGERFALCSTFKVFAAGAVLRDHA --GSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP -AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPEALGASLERLTVGDELSGAARE -QLLTWLKGNTTSDRRFRAGLPRGWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSK -DAPDATVDEALIADAAAVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas panacihumi TaxID=676599 RepID=A0A0R0A474_9GAMM ----LDAAWAEIEQRAGGRLGVALRD-AEGRYLaGRREDERFPMCSTFKFLLAGAILHEVD -AGRLRLDRRVPIAATDLLGNSPITERHVGPKLSVGELCQATIIRSDNAAANLLFPLVGGP -EGLTAFLRASGDAVTRIDRNEPTMNLFAPGDDRDTTSPAAMAGNLRRLLLGDVLKPASRG -QLTAWLRDNRTGDKRLRAGLPAGWQVGDKTGFNGEDTTNDIAILWPPGGAPLLLATYLQG -AQVDPDGQNAALASVARAVS--- ->[subseq from] Class A beta-lactamase n=1 Tax=Telmatospirillum sp. TaxID=2079197 RepID=A0A6A8QL72_9PROT ---DFERRLKTLETASGGRLGVAFVDKETGAVR-GHRLNERFLMCSTFKLLLVGAVLSQVD -SGKERLDRRIMIRSEDILEYAPVTRTHLDGPMTVSELCDAAMTLSDNTAANLLLDALGGA -ETLIAFARSLGDPVTRLDRKEPDLNLMVADDIRDTTTPAAMAADLDALILGDRLSPEMRH -RLTKWLIGNQTGAHRLRAGLPHGWKIGDKTGSGV-GIANDVALVWPPGRAPFLLSVYLTG -ATGTAVQRDAVLAETARLAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NEAU-S7GS2 TaxID=2202000 RepID=A0A2U8VL18_9ACTN ---RAAKDLAQVERRYHSRLGVYMLDTGTGRTV-TYRAGERFAHASTFKALAAAVLLKRGT ---DDELNSVINYRASDLEDYAPITKRHVGEGMTLRDLIKAAVQYSDNTAANLLLDRLGGP -AGLQKALRGMGDRTTRTDRTEPALNEAKPGDPRDTSTPRALGTDLRRFVLGDVLPEGRRQ -LLTHVLRGNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRNDIAIVWPAGGSPIVVAVLSDR -GSKDAASDDALIKDATKT----- ->[subseq from] Beta-lactamase n=1 Tax=Mycetocola zhadangensis TaxID=1164595 RepID=A0A3L7J112_9MICO ---AADAQFGELEAKFDARLGVYALDTGTGLAL-EYRSDERFAYASTIKVFASAVLLDQTT ---DSELDSLVRYDESDLLDYAPITEQHVDTGMTLRELGDAAVRYSDNTAANLIFERIGGP -TGLATALKAMGDDVTQVDRTEPELNETTPGDPRDTTTPEAFAVGLEALILGDALELADRE -TLTEWLVGNTTGDNLIRAGVPTEWTVGDKTGSAGYGTRNDIAVIWPTEGDPIVLAVLSSR -AEPDAEYDDDLIAEATAVAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis jejuensis TaxID=330084 RepID=UPI000526C0E9 -----QPDFAALEKTFGARLGVYAIDTGTGREI-AYHADDRFAYASTHKVFTAAAILHRGD -----DLHRMITVRSSDLVPYSPITEKHLDTGMSLQSVLDAALRYSDNTAGNLMFREIGGP -EGLTADLHRSGDTVTHVDRIEPALNDTAPGDIRDTTTPRAWAADLRAAVLGSALGPDRQA -VLTGMMRASTTGGNLIRAGVPDGWQVADKTGTADYATRNDIAVVWPPNRAPIVLAVLSDR -PQKDAKADDKLIAQATAAVVK-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 62 TaxID=2035203 RepID=A0A2G6Y669_9BURK --qQWQQALAQIERNAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD -QGKERLDARVQYPASEVVDYSPVSGSKAGAGLTVGELCSATVSLSDNTAANLLLARHGGP -SALTAYLRTLGDTATRLDRNEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGDALTPASRA -TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ -SKAKPEQREAAIAEVARSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia bhagyanarayanae TaxID=1215925 RepID=A0A543EXQ2_9NOCA -------HLIDLERKFDARLGVYALATGTGAVI-AHRADERFAFCSTFKGLVAAAVLQRNP ---LSHLDTVVSYTEADLLKNAAVTPKHLDTGMTIRDLCDAAVRFSDGTAGNLLLRDLGGP -AELTAYARGLGDTVTRMDRTEPTITQAIPGDPRDTTSPRALGTDYQQIVLGDALPADKRA -FLRDLLERNTTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIGIVWPPDSAPLVIALMSSK -ATADARYDQALLAEAAAYVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0005A06F5E ---ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD -HDGTFLARRIRYTAADVKRWSPRTEENLARGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHRDRE -RLTRWMLANTTSGERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR -SLEDAPVVDPLVAEAAALVAA-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00119F647D -----ADDFAALEKASGGRLGVTLLNTATGARV-GHRQDERFPMCSTFKFVLAATVLHLAD -QGTLALDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRAHGDAVTRNDRLEPDMNRFAPGDPRDTTSPAAMAASLQRLVLGEVLKPASRL -QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI00138F784F ----AAADFAALEAAAQGRLGVAVLDAAGGRYLgGHRPDERFPMCSTFKAVLSAAVLAQAD -RGALELDLRLPVRRSDIVSHSPVTRRHVGKDLTVRDLCRATMTTSDNAAANLLLGRIGGT -AGLTAFLRGIGDEVTRSDRMEPEMNRFAPDDPRDTTSPRAMAASLARCVAGDVLAPASRL -QLADWLIDNRTGDDCLRAGIGDGWRVGDKTGSNGTDTRNDIAIVWPLQGRPWTVAAYLQG -ARVDSPARDAVLARAGALAAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_032 TaxID=2175659 RepID=A0A2W1U1W9_9MICO ---AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAAAVLDAAA ---PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRELLAAMVRSSDNTAANLLVARVGGP -AAVQRWLRGIGDDVTRVDRVEPALNEAVPGDERDTTTPEQFAADLRTVLLGGALDPDDRA -LLVDLMRGTTTGAGTIRAGVPEEWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH -DTADAEPDDALVAAATRTAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. wa22 TaxID=1828244 RepID=A0A5Q4SIU1_9ACTN ------RAFQELERRFGARLGVYAIDTGSGASV-THRPDERFAYASTCKALLAGAVLDGHT ---LQQLERRVRYGPGDLVANSPVTERHVDAGMTLRALCDAAVRHSDNAAANLLFDEIGGP -RGLQDALIALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGTEKRA -VLTDWLRRNTTGGALIRAGAPADWPVGDKTGTGGYGTRNDIAVLWPPESAPVTIAVLSRR -STRGAKPQDALVAEAARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. N3-2A TaxID=2014541 RepID=A0A220RC61_9GAMM ---NLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGSEQLERQVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP -QAVTAFVRDLGDSVTRLDRWETELNEAAPHDERDTTTPNAMVSNLEKLVVGNALSPQSKN -QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNSAIAELGSVI---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. MOS003 TaxID=2133946 RepID=A0A2T2Q666_9BRAD -------ELETYERESGGRIGVYAENLATGKKL-TWRADERFVMCSTFKASLAACVLARVD -HGEEKLAATIAYGKTDLLEYAPVAKQNLAAGMSVGDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPASRA -LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILIAAYVQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A2B1MP75_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKED----AKLIADATKIVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. OK885 TaxID=1882770 RepID=A0A2N3ZD18_9ACTN ---------RELEARHGARIGAFAYNLRTKATV-RHRAAERFPICSVFKTLAAAAVLRDLD -RHGETLARRIHYTVADLAGYSPKTGEHLAGGMTVGELCGAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAADSPLVAATASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCBAU 43298 TaxID=1128178 RepID=UPI0004B277E3 ----APAELEAYERDSGGRVGVHAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEHLAAMIPYGQADLLEYAPVARQNLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVLGEALSAQSRL -QLTDWMVNCKTGANRLRGGLPPSWKIGDKTGNNGKDASGDIAVVWPKPDVPILIAAYTQG -GSPNAAQIAALFAQIGRMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=UPI000BA53BB3 ------ASFSSLEETYDARLGIFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGFEDGLRKIGDQVTNSERIEPDLNNTQPGDTRDTSTPKAMAESLREFALEDHLSADKRQ -LLIDWLKGNTTGDELIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPEEEPIVLAIMSDH -DEADANANDDLIAEAAETAV--- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium 62-8 TaxID=1895708 RepID=A0A1M3A9C1_9PROT -------PFRAIEARTGGRLGVAVRDTASGRHF-AWRGDERFAMCSTFKFLAVAMVLERAA -AGATDLDRAIAYGRADLLDYAPVTAKHVKAGMSLRDLCAAAIEWSDNTAANLILKQIGGP -AGLTRWLRGHGDTVTRLDRTEPTLNTAIAGDPRDTTTPIAMLADMARILVSEK-SAAFAA -PLLIWMRECRTADSKLRAGLPRDWRAGNKTGSGRNGTANDIAILWPPGRAPLLVAAYLTG -AKADAAARDAALADAGRVVAARf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces diastatochromogenes TaxID=42236 RepID=A0A233S7T5_9ACTN -----HTELGDLEQRYGARLGVYAHNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG --GCAPLDRVIHYPPRDILPNSPKTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP -EGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPEAIGRSFERLTLGRALDGTGRE -QLVTWLKGNTTSAERFGRGLPQGWVLGDKTGTGDYATANDIGVAWTTRGTPVVLAVLSTK -AAKDAPVDNALVADTARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID724 TaxID=2690324 RepID=UPI001360F16E -----GRAFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERVVTYRREDLVDHSPVTEKHLATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALGGPERA -RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TAADADHDNTLIAKAASAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00035CBA64 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRHSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. MMS16-CNU292 TaxID=2567942 RepID=A0A540WG95_9ACTN -----TEAFAQLEQQFGARVGLYALDTGSDREV-AYHADDRFAFASTIKSLSVGTLLRHAS ---DAELDKVVTYHQEDVLSWAPVTSKHVADGMKLRDLATAAIEQSDNTAANLVTAELGGP -AAVQQALRDLGDRTTNVDRTEPTLNEATPGDTRDTSTPRAMATDLRQYVLGGTLAGDHRQ -LLTDWLVGNTTGGPYIRAGVPTGWKVGDKTGNGGYGTRNDIGILWPNDGAPIVIAVLTDR -GKPDAKSDDALIAQATKAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0004963790 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRHSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=A0A2A2CS85_9VIBR --dSLTKQIALIEQQSGGRLGVAVLDTQNHKQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP -EQVSQFVRSLDDKVTRLDRFEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753545D ----ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAKTf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753675A ----ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAKTf ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI000A381CB8 ------PDFAPLERSFDARLGVYALDTGSGREV-VHRADERFGYASAHKAFSAAAVLQRTS ---IEDLAKVLTYRRADLQENSPVTEKHVDTGISLRDAIDAALRYSDNTAANLLFQQLGGP -PGLAAALRAIGDTTTHVDRTEPALNDLAPGDIRDTSTPRAMAGTLRTFALGDALPPEKRT -MYTDMMRANKTGANVIRAGTPAGWAVADKTGTGEYATRNDIAVVWPPGRAPIVLAVMSSR -QAEHAEHDDRLIAQAAKLVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075V010_9PSEU ---QFHDRLMELENKFDARLGVYALDTGGGGTV-EHRADERFAFCSTFKGVATAAVLQRNP ---LSHLETRVSYSRDDLMKHAPVTERHVATGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AALTAFTRGLGDTVTRMDRVEPAITEATPGDLRDTTTPRAFAADYREIVLGDTLTAEKRD -FLRDLLQRTVTGAGRIRAGLPSGWTIAGKTGTGEYGTLNDIAVLWPPGKAPIVLAVMSSK -PAKDAPYDEALLAEAAKYVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. Leaf33 TaxID=1736215 RepID=A0A0Q4KNC8_9SPHN ---ALATAIAAAERRSGGRLGVAVLDLATGARF-DHRGDERFAMCSTFKFPLSGAVLAAAD -AGRLRLNRAVPVPRAPLPGNSPVVSKHKGSAMTVEQLCAATMTFSDNAAANLLLPLIGGV -DGFNAFVARLGDRTTRLDRQEPELNTAIHGDDRDTTTPTAMLNTMRALLFGPALTPAARA -KLTGWLVANTTGGTRLRAGLPRGWRVGDKTGSGENGTYNDVAVIWPGTRRPILVTCYLTG -ATVPQRAAHRIHADVGRAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00036DDC91 -------GFRRLEKRFDARLGIYAIDTDTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A2W6U227_9GAMM ------ADFAALEKASGGRLGVCLWNPASGARY-GHRIDERFPMCSTVKYPLAAAVLRRAD -AGQLSLDQRVPVRASDILDHSPFTERHVGKTMTVRDLCRATMIVSDNAAANLLLPLVGGP -AGLTAFLREHGDRVTVSARNEPELNRFAAGDPRDTTSPAAMAGNLQRFLLGDVLGEASRQ -QLADWLIDNQTGDARLRAGLPQDWRVGDKTGSNGSDTSNDIAVLWPLGGTPWLLSSYLQG -SALDDDGRNGILRQVGELA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces hainanensis TaxID=402648 RepID=A0A4R4TK34_9ACTN ---SLAREFEALEREFDARLGVYVLDTGTGQEV-AYQADERFTYASTFKALAAGAVLHEYG ---SEGIDEVVTYTEDDLVDYSPVTENFVETGMSLSELCAATLWYSDNTAGNLLFDALGGP -DGLEAVLEELGDDVTEMDRYETELNEATPGDIRDTSTPRAFATNLREFLLGDILDPDERE -LLRMWMVTNTTGETLVNAGVPDGWTVADKSGAGGYGGRNDIAVVWPDDGDPLVMAIMSAH -DEEDAEHDDALIAEATAVAVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum chlorophenolicum TaxID=211589 RepID=UPI00067BC1BB ----IAQKLAELEKQSGGRLGVMAIDNASSDRI-GYRETERFPFCSTFKLILVSAILNRSL -EDSTLLQRRVRYDAADLVAYSPVTEKAVGAGLSVSGLCAAALQYSDNTAGNLLIRELGGI -GAVNEYARNIGDESFRLDRMETEINSAVPGDDRDTTTPLAMAQSLQRLVLGEILPPLQRR -MLVDWMRGNTTGGTRIRSAMPSDWVIADKTGGGDYGTTNDVAVIWPGSESPVILAIYFTQ -TVQDAPPRNDVVATAARIIGEHf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) TaxID=953739 RepID=F2R4A0_STRVP ---ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD -HDGTFLARRIRYTAADVKRWSPRTEENLARGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHRDRE -RLTRWMLANTTSGERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR -SLEDAPVVDPLVAEAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. GS7 TaxID=2692234 RepID=UPI001318093A ----AERELRELERRYAMRLGVYARNVRTGEVV-AYRARERFAMCSTFKAFAAAAVLRDQA --RCAPLDKVIHYPPADILPNSPKTAQHVDTGMAVGDLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFFRSIGDRVSRLDRWEPDLNSALPGDLRDTTTPEAIGGSCERLTVGRALADADRE -HLVTWMKGNTTSEERFRAGLPRDWVVADKTGTGDYASAHDIGVAWTTRKTPIVLAVLSTK -ATRNAPVDNAPIAAAARIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cyaneus TaxID=1904 RepID=UPI000FF8AFDA ----VTARLRALEEQHGARLGVFAHNLATKQTV-RHRADERFPICSLFKTLAAAAVLRDLD -RDGEVLAKRIHYTAADLVENSKETEKHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAVTRFARSLGDPVTRLDRWETELNSAEPWRTTDTTSPRAIGRTYARLVLGNALNRPDRD -LLTYWLLNNTTSGNRLRAGLPKTWAIADKTGGGFYGTNNNVGIAWTENGTPLVLAVQTTK -PEQDAAPDHALIVETAALLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus innexi TaxID=290109 RepID=A0A1N6MY37_9GAMM --eQMVHQLTALEKSANGHLGVALINTADHSII-GYRANERFPLCSTSKLMAVSALLKKSE -TDEKLLNQRVHYKQADLVEYSPITEKHIEDGMTLTELSAATLQYSDNTAMNLLLNQLDGP -ESVTTFARTLGDNIFRLDRKEPELNLVQPGDKRDTSSPQAMAESLYKLALGDALATNQRA -QLVEWLQGNTTGNASIRAGLPKNWVVGDKTGRCDYGSTNDIAVIWPTNRAPFVLVTYFTQ -PGKNAKARPDILAEATRIMIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD52300 -----EAQIAALESKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -QAITTFCRSIGDELTRLDRTEPTLNYDTANDERDTTTASAMLENLRRLLFTDVLTPASRS -QLAAWLITNKTGDTRLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPSKRAPIIVTAYCEV -PAIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. QHH-9511 TaxID=2684468 RepID=UPI001315EDD9 ------GEFAELERTFDARLGVYAVDTGTGREV-AYHDGERFPYASTFKALAAGAVLRTYS ---LGGMGRVVTYSTKDLVAHSPVTEKHVKTGMTLDALCDAAVRYSDNTAANLLLDQLGGP -KGLDAVLEELGDDVTHMERREPELSRWTPGSAPDTTTPRALAGDLRAFVLGDVLGPPERA -RLTHWLRTNTTGDETIRAGIPKGWAVGDKTGTGGYGARNDIAVVWPPGRAPIVMAIMSRR -AEAGAEHDDRLIARAASVAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudoxanthomonas composti TaxID=2137479 RepID=A0A4Q1JVQ6_9GAMM ----LRKALRRIEAQSQGRLGVSVLDTASGQRA-GWRQTERFPMCSTVKFPLATAVLARID -AGTLRAEQRIVIARKDLLPYSPYSEQHIGGQVDVLTLCEAAMTQSDNAAANLLFALVGGP -AGLSAYLRGIGDAQTRSDRIEPMLNTCIPGDARDTSTPEAMTDTLQRVALGDTLSAASRA -RMQAWLRGCKTNAARLRAGLPPGWTVGSKTGSSSNGTSNDVGILWPRDAAPLVVSCFLTG -SPQDAAARDAVIANVGAAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella hinzii TaxID=103855 RepID=UPI00114EBF4E ---DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA -RGEDDLSRPMRLSAADIVDYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP -PGVTAYARALGDGATRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDALPAPERE -RLRDWLMQCRTGQQRLRAGLPASWSLGHRTGAGGHGTCNDIGVAWPTPTTPVVISVYLTE -SPLDLPGRERVLAEAARILAH-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas venusta TaxID=44935 RepID=UPI0011BEDB59 ---KLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACAALLQRVD -EGSEQLERRIKVSASDIVTYSPVTEAYADNRISLFELCEATLTTSDNTAANLILQAIGGP -QAVTEFVRALGDSVTRLDRWETELNEAAPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN -QLREWLINNEVADGLFRSQIPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNSAIAELGSVI---- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella sp. NEAU-YY265 TaxID=2293569 RepID=A0A418KTH7_9ACTN -------------RTHDVTLGVSATNLATGARI-AHRAADRFPILSVFKSIAAAAVLRDLD ---ETRLDHRVWYPPADILPSSGITAEHVDTGMTVAELCDAAIRYSDNAAGNLLLREIGGP -RGLTAFARSIGDGATRLDRWEIELNSAEPGDERDTSTPAALARTFAGLLVGDLLRPGDRR -RLRDWMLANTTSGPRFRDALPEGWRLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR -SERDAVRVDAALADVARLVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas codiaei TaxID=56463 RepID=A0A2S7CYN0_9XANT ----LRTQWADIERGTGGRLGISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRQVD -RGRLTLAQAVRIRASDMLEHAPVTKGHVGGALSVGELCRATMIYSDNPAANLLFPLVGGP -PGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGGALQPASRK -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDDAARDAALKAVAVAVREW- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hokutonensis TaxID=1306990 RepID=UPI0003659482 ----VSARLAALEEQHTARVGVFAHHLGTRKTV-VHRADELFPMCSVFKTLAAAAVLRDLD -RHGEVLYRVVHYTEADLVDGSDRTRAHLADGMTVEQLADVAIRYSDNTAGNLLLRALGGP -TAITRFARSLGDPVTRLDRWETELNSAEPDRITDTTSPRAIAGLYGRLVLGDALRRPDRD -RLTAWLLNNTTSTARFRAGLPATWTIADKTGSGDYGTANDVGIAWTEAGDPVVLAVLTTK -PTPDAPYDNQLVAETAELVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075966B4 ----ALDSIRSIEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALDKPVKYGKADLLDYAPVAREHVGRGMTIDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAKTf ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI000B96169B --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -RGEFALNDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLVAQKLGGP -QKVTALLAGLGDNVTRLDRKEPELNSAVPGDLRDTTTPLAVSHTLEKLTLGDALKPESRA -QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora hirsuta TaxID=1837 RepID=A0A5M7B8H2_SACHI -------DLAELERRYDARLGLHATNVRTGRML-VNRPDERFALCSTFKTYAVAALLRDHG -LSSGYFDKVIRYTRDDLVSHSPVTEKHVDTGMTVRELCEATMTVSDNTAANLLLRERGGP -GSIAPFARSIGDATTRLDRWETDLGTAIPGDERDTSTPAGIAAGYRALVLGDALAAPERD -QLTNWLIANTTGDKTIRAGLPPTWRTGEKTGSGDYGTRNDVGVTWTEDGTPIVIAILTSR -PKQDDERRDALLADTARAVAAH- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-1381 TaxID=1463829 RepID=UPI0004BEC6C0 -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDQRVTYTRKDLVANSPVTEKHVGTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLDGALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Marinobacter TaxID=83889 RepID=A0A1I4L2Y2_9ALTE ----LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD -NGTVDLDRRVIFSKDDLVTYSPVTETRVGEEMSLRELCEATMATSDNTAANLVLGAIDGP -DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD -TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ -TGASFDERNGAIRDLGGAIVKHf ->[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=A0A221VY17_9PSEU ---AAQEALESLEAEFDARLGVYAIDTGTGEEV-EYRADERFAFASTYKVLAAAAVLEQNT ---LAELDELVAYDESDLVTYSPVTEGSVGTGMTLRQLAEAAVQYSDNTAGNLLFDELGGP -AGFAAALARVGDQVTVAEREEPDLNDYVPGDDSDTSTPEALATTLSSYALGDTLSPDKRE -LVTQWLIGNTTGDDLIRAGVPADWVVGDKTGAAAYGTRNDIAVVWRPDGDPIVIAILSDK -ADPEAQYDDSLIAEATSVTID-- ->[subseq from] Beta-lactamase n=1 Tax=Sphaerisporangium sp. LHW63015 TaxID=2248750 RepID=A0A366LNN7_9ACTN ---AVRRELRALEASFDGRIGAYAIDTATGRTI-GHRADERFPLASTFKAVVAAAVLHKAR -TDPGLLKRVVRWTAAEIEPNSPVTQEHVKSGLTVARLCEATVTQSDNTAGNILLKEIGGP -AGLTRYFRSLGDRISRSDRWEPEMNHWKPGEKRDTTSPAAMANDFRRLATGDALNAKDQK -RFTTWLVASKTGGNRIRAGLPSTWKVGDKTGTGGYGTANDVAVIWPPKAAPIVMAVYTSR -KPAEADADEKVLAKTATALVR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces phaeoluteigriseus TaxID=114686 RepID=A0A1V6MS48_9ACTN -------RLRALEEAHGARLGVFAYNVRTRRSV-RHRAAERFPVCSLFKVLAVAAVLRDLD -RDGEVLARRIHFTEDDLVENSPVTEEHVLDGMTVAELCDAAIRRSDNTAANLLLRELGGP -AAVTRFARSIGDRFTRLDRWEPELNSAEPWRVTDTTTPYAIGRSYARLVLGDELAADDRR -RLTDWMLANRTSDNRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQVTA -PEREAAYDHELIVETTKVLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0P0GHP6_KLEPN ------------------------------------RPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNDAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKH- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora pallida TaxID=145854 RepID=A0A1C6TIM4_9ACTN --------FGALEARFGARLGVYAVDTGSGVTV-VHRPDERFAYASTFKALAAAALLDATS ---TAELGRVVRYTRDDLVPHSPVTERHVTTGMPLRDLADAAVRYSDNTAANLVLAELGGP -PGFAGHLRALGDRTTRPARTEPALNRTAPGDDRDTSTPRALATNLHAYVLGDALSAEDRA -LLTDWLRRNTTGHKLVRAGVPAGWTVGDKTGTAGFGTRNDIAVLWPPEGAPVVMAVLSSR -DVRDAKPDDALIAEATRLTID-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium zhanjiangense TaxID=1325107 RepID=A0A4Q0QPD4_9BRAD -------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGEALSLTSRA -QLTEWIVNCKTGANRLRGGVPAGWRIGDKTGNNGKDASGDIAVVWPRPDAPILIAAYTQG -GTPSAAQIAAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A126Y456_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRPDELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010229282 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRPDELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces libani subsp. libani TaxID=68044 RepID=A0A640TVZ5_9ACTN ----LASEFKKLERKYDARLGVYAVDTGTGREV-AYKDGERFSYNSTFKALAAGAVLRKHS ---PSAMDRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP -KRLEGVLKGIGDDVTRMERIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGDVLDKGDRK -QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR -FKKDADFDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Marinospirillum celere TaxID=1122252 RepID=A0A1I1JB69_9GAMM ----LLAELKRIESNLDARIGFFAQDTETGKQW-EYNADQRFALSSTFKTLACAALLQRVD -EGSEQLSTSVSVSSADLVTYSPVLENYADTRITLFELCEATMTTSDNTAANLILQRLGGP -ESITNFARQLDDSVTRLDRWETELNQATPGDERDTTTPKAMVSNLEHLLLGAVLSTESRN -QLQTWLIDNQVADALFRSSVPDGWIIGDRTGAGGYGSRSITAVIWPPERSPVFVAFYITE -TEASFEDRNASIAQLGRVFM--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Acidovorax TaxID=2684926 RepID=A0A2G6SWY7_9BURK --qQWQQALTQIERNAQGRLGAALLDTGSGLAL-GWRQDERFAMCSTFKLPLAGWMLALVD -QGKERLDARVQYPASEVVDYSPVSGPKAGAGLTVGELCSATVSLSDNTAANLLLARHGGP -SALTAYLRTLGDTVTRLDRNEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGDALTPASRA -TLQRWLVETSTGDKRLRAGAP-GWRVGDKTGTAGSGTTNDIGVLWPQGGAPVLLTCYLTQ -SKAKPEQREAAIAEVARSAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YIM 132580 TaxID=2691958 RepID=UPI00136D45AF ----TDRAFAELERKFDARLGVYAVDTGDGRTV-THRPDDRFAYASTCKALLAGAVLAGKS ---LPQMERLVRYGKEEIISNSPITEKHTATAMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQGALRGLGDQVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYALGSALPEEKRD -VLTDWLKRNTTGDHTIRAGTPRGWVVGDKTGTGGYGTRNDIAVVWPPDAAPIALAVLSRR -DSKDAERDDALIAGAAKVALGAf ->[subseq from] Beta-lactamase class A n=2 Tax=Rhizobium sp. BK333 TaxID=2512158 RepID=A0A4V3CLE7_9RHIZ --qAADAKLAELERKHPGRICVSILDLASGKRI-EHRANERILMCSTFKALAAALVLVRVD -KGEEKLDRRIKFSKKDLVSGSPVTQARVGEPMTVAELCDAAVTRSDNTAGNVLLASFGGP -AALTAFCRTLGDDVSRLDRIETELNYDGPDDIRDTTTAAAMLENLRKLLFTDILSGASRS -QLAAWLITTKTGDARLRAGLPKNWLVGDKTGTNGYGNANDIAVIWPPDRAPIIVTAYCEI -PSIPAAARDAVIADIGRIAS--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium oxalidis TaxID=944322 RepID=A0A512IYS0_9RHIZ ----ARARLRAIEDRLGGRLGVAVRDTGSGRAL-LYRADARFPMCSTFKVLAAAAILARVD -AGGERLERTMPYTAADLDSYAPVTEA--GRNMSLTDLCAAAVTWSDNTAANLMLRALGGP -PALTAWLRGIGDQTSRLDRTEPSLNSALPGDLRDTTAPVALAEDLERLLIGDVLSAASRE -RLEGWMVAARTGLKRLRAGLPADWAVGDKTGTGDNGTANVVAILRPPGRAPLVAAVYMTG -SGCTAEERDAAHAEIGQLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM3983 TaxID=1038867 RepID=UPI00040288B1 -------ELESYERESGGRIGVYAENLATGAKL-TWRADERFVMCSTFKASLAACVLARVD -RGEEKLAAMIPYGKADLLEYAPVAKQNLSAGMSVADMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTISRLNHNEPELNRSPPGDPHDTTTPAAMAGNLKRLVTGEALSPASRA -QLAEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG -GTPNTAQIEAAFARIGRMVAE-- ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B2W9S6_9ACTN -------DFQRLERTYGARLGIYAVNTGNGREV-AYRDTERFAYASTFKAFAAAAVLREYS ---LNGMGKVVKYSRADLLSNSPVTAKHVETGMTLRELCDAAVRYSDNTAANLLFAALGGP -KGLAAALAEAGDTATRVERREPELNEWTPGATRDTTTPRAWAANLRAFVLGDALGKDERA -QLAQWLRTNTTGDELIRAGVPKGWTVGDKTGGGGYAVRNDIAVVWPPNAAPIVMAIMTNR -GTADAPYDNKLIAESASVVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ventii TaxID=2720606 RepID=UPI00143C8F18 ---SAASTFEQLENEFDARLGVYALDTGTGEEV-EYRSDERFAFASTFKALAAGALLAQYG ---LDGIDNVVAYDKADLISHSPVTERFTDEGMTLRDLAAAAVRQSDNTATNLLFDALGGP -TGLQAALRGVGDETTNVDRLETELNEATPGDDRDTSTPRAMAETLNEYVFGDVLDAQESD -QLVEWMTTNTTGATLIPAGVPDSWTVGDKSGAGGYGTRNDIAVLWPEEGEPIIMAVFSSR -DEEDATYDDALVARAATSA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID2119 TaxID=2690253 RepID=UPI0013689057 ----TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLSGAVLAKKT ---LPQMERLVRYGKEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGSALPAEKRA -LLIDWLRRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR -DIKNAETDDALIAGAAKVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Salinispora arenicola (strain CNS-205) TaxID=391037 RepID=A8M7Y4_SALAI -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] GPC-1 n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A6B9L444_PSEAI --eNLAQRLAALEARHGGRIGVAIHNLSTGARL-GHNTDERFLMCSTFKALLAGHILVRVD -RGEETLDRRIVVKEADLVDWSPVVEKRIGGDISIAELCEATITLSDNAAANLLLAASGGP -KAVTAFLRGLGDEVTRLDRTEPTLNYETPGDERDTTTPSAMVETLRRLLFTDVLSARSKA -QLAAWLIMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAVAWSPDRGAVIVAAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia MF89 TaxID=1333853 RepID=T5KCE7_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDVRNDIAVLWPRGGASWVLTAYLQA -SAISNEQRAQVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. FT05W TaxID=2202417 RepID=A0A2V2QGM6_9ACTN -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGTHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGEEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=A0A4Q9HJE2_STRKA ---DAARQLRDLEREHGARLGVFGWNTVTGASV-SHRGDERFPMCSTSKTPAVGAVLRDLD -HDGTFLSKIIHYTERDIERGAPVTGRNLAQGMSVADLCGAAISYSDNTAVNLLLAELGGP -TAVTRFCRSIKDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYARLALGNALAAADRK -LLTGWLLANTTGDKRLRAGLPGNWRVADKTGTGSYGTANDVGIAWPPGQGPIVLSVLTTR -PDADAEADDLLIARAATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-646 TaxID=1463917 RepID=UPI0007C51A0C --aAVVDRLRELEQQHGARLGVFAHNVRTKRTV-EHRADELFPICSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP -TAITRFARSVGDPVTRLDRWETDLNSAEPWRITDTTTPRAIGRSYARLVLGHVLDRRDRA -LLTHWLLGNTTSGNRLRAGLPSTWTVADKTGAGFYGANNNVGIAWTPDGTPVVLAVQVTK -PERDAAWDHELIAEAAAVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0000EBA8BE -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Jeotgalibacillus sp. S-D1 TaxID=2552189 RepID=A0A4R5XM31_9BACL -------GFMDLEKKYDARLGVYALDTGSNQSV-SYREEERFIYASTHKPLAVGALLQKKS ---LEDLEELITYTKEDLVNYNPITEKHVDTGMTLKELSDASIRYSDNTAANLIFNAIGGP -EGFKEVLQEIGDNTTEPERIEPDLNDVEPGETRDTSTPKALAESLQAFTLGDALPPEKRD -LLNDMLINNTTGDALIRAGVPEGWQVGDKTGAGSYGTRNDIAVIWPPEGDPIIIAILSSR -DEADAEYDDALIAEATKKALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Cysteiniphilum sp. JM-1 TaxID=2610891 RepID=UPI00124881FF ---NVNNNFKALEKQYGGQLAISAIDTSNDQVV-DYHANKRMPMCSTFKLMLVAAVLNKSV -NEPKLLEKKIEYTQKDMVNYSPYTKENLGKGMTVSALCHAAM-LSDNTAANLLLKELGGL -DKLNQFARSIGDTTFRLDRYEPYLNTAIPGDKRDTTTAKAMSQSLDKIVLGNVLPAMQRD -LLIKWMQTNTTGDKRIKAGVNKSWIVGDKTGTGDYGTTNDIGVIWPNKCKPIVISVFYTQ -DKQDAKAQDVVIQKATSFAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=A0A0M4DNU1_STRPR ------RAFARLQREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEHNS ---LAGLDKVVRYTRDDLVAHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP -KAFQAVLAALGDTTTHADRLETALNAATPGDIRDTSTPRALAHDLRAYALGDVLDAEKKA -LLTHWLKGNTTGDALIRAGVPDTWQVGDRTGAGAYGTRNAIAVAWPPGAAPVVIAVLSSR -ATEDAEYDDRLVARATEVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00042569BF -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces galilaeus TaxID=33899 RepID=A0A5J6EPH8_STRGJ ------ARLRALEEAHGARLGVFAYNVRTRRSV-RHRAAERFPVCSLFKVLAVAAVLRDLD -RDGEVLARRIHFTADDLVENSPVTKDHVADGMTVAELCDAAIRRSDNTAANLLLRELGGP -TAVTRFARSIGDRFTRLDRWEPELNSAEPWRVTDTTTPYAIGRSYARLVLGDELAAHDRR -RLTDWMLANRTSDNRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQVTM -PEREAAYDHALIVETTKLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinicola halophilus TaxID=184065 RepID=UPI000DA21BB3 ---DLERELAALERRHGGRVGVALMNVATGAVA-SHRGDERFLFNSTGKVFMVAAVLARVD -SGEESLDRRIEIEASDIGEWAPITEQHIGSPMTVAALCQAAMAWSDNTAANKLIESVGGP -EPITAYLRSVGDDTTRLDRWEPELNADHEGDERDTTTPLAMMQTLNTLLLGEALSPASRH -QLAAWMIAGKTGDARLRAGMPAGWLIGEKTGTSSAGNANDIGIAWPGDRGAVIAVAYTYL -PEASKTQRDEVVAEIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia miyunensis TaxID=282684 RepID=UPI000831B00B ---ELSGRFGALESRFGARLGVFALDTGSGRTV-EYRADERFAFCSTFKALAAGAILTTAN ---NAELDRRITYTATDLTAYAPITRQHVADGMTVRDLLDAAVRYSDNTAANLLFGLMGGP -AGFQRDLRNLGDQVTRSDRLEPMLSDATPGDPRDTSTPRAFAADLRTYVLDAALPTDNRA -LLATMLRANTTGAGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPLVLAVMSTR -HGHDDTYDNALIAQAANAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. CCBC3-3-1 TaxID=2490851 RepID=UPI0011BDDFED --dSLSQQLASLEREVNGRIGLALLDTHTGEKL-TYRGDERFPLCSTFKLLAAAAVLRRSE -QQPDLLLQRMHWTPAEHLAYMPVTEKHQDEGMTLEALCLAALQYSDNLAGNLLLKTLGGP -AGITDFARGLGDNVTRLDRNEPALNTAVPGDLRDTTSPLAMLGNLNTLLLGSGLAPSSQE -KLASWLKGNTTGKKAITAAVPAGWIVGDKTGSGDYGTTNDVAILWRPDATPLLMAIYFTQ -QGKDARSRQDVLAKTARLAL--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces griseus TaxID=1911 RepID=A0A2X2M8B0_STRGR -------AFEALEKEYAARLGVYAVDTGTGTTV-AHRDGERFAYASTFKALAAGAVLRRYG ---LGGLERIVTYRREDLVDHSPVTEKHVATGMSLGALCDAAVRFSDNTAGNLLFDAVGGP -RKLQAVLAGLGDEVTRMVRRETELNEWTPGATRDTSTPRALAEDLRAFVLGDALGGPERA -RLTQWLTTNTTGGELIRAGVPKGWTVGDKTGAGSYGTRNDIAVVWPPDAAPLVLAVLSNR -TAADADHDNTLIAKAASAAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2PYG6_9PSEU ---SAQADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP ---LADLDRTVTYSQKDLVSNSPVTEKHVATGMPLRAVIDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPELNDTFPGDKRDTSTPRALAVSLRAFALGNALPEDKRQ -VLVDIMRANTTGDENIRAGVP-GWPVADKTGTAEYGTRNDIGVVWPPNRAPIVISVLTDR -ATKDAKIDNALLAQATAAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CT34 TaxID=1553907 RepID=UPI0005BAD030 ---RAERELRELEQRYAMRLGVYARNVRTGQVV-AHRAQERFAMCSTFKMFAAAAVLRDHA --RCAPLDKVIHYPPADILPNSPKTAQHVDTGMPVGDLCAAAIQYSDNAAGNLLLRQIGGP -AGLTEFFRSLGDRVSRLDRWETDLNSAVPGDLRDTTTPEAIGGSCERLTVGRALADADRE -QLVSWMKGNTTSGERFRAGLPRDWVVADKTGTGDYASGNDIGVAWTTRKTPIVLAVLSSK -ATPKAPVDNAPIAAAARIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus dictyosporus TaxID=1523247 RepID=A0A1I5U1Y0_9ACTN ---DVSAEFAALEARFDARLGVFAVDTGSGAIL-EHRADERFAYASTIKALAAGALLTRTS ---PADLQRPVPVTPADLTTYSPVTETRVGGSMTLAELCDAAVRFSDNTALNLLLRELGGP -AGLDAALEAIGDDVTEVARTEPELNSAVPGETRDTTTPRALAGSLRAYAVGPGITEEDRA -QLLDWLRRNTTGDALIRAGVPADWDVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR -DEPDADPDDALVAEAARVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=A0A316CNN3_RHILI ----VLPKIRRIEAKSGGRLGVACRIAGTSAQF-GYRENELFPMCSTFKTLAAALILHRVD -GGIEQLERSIKIPHNAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP -PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTISPLAMVEDYERLALGNSLSDKSRA -QLVEWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG -TKQSLTKRNAVIASVSRTLVE-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax sp. 99 TaxID=2135634 RepID=A0A2U1DZH4_9BURK ---AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR -SIAPPEQRDAAIAQVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. LVM 105 TaxID=2341115 RepID=A0A5E8VJA4_9BRAD -----PAELESYERESGGRVGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMVPYGKADLLEYAPVARQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDNTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGDALSPASRA -LLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDAACDIAVVWPKPDTPILIAAYVQG -GAPNAAQIEAAFARIGRTVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Sediminibacillus massiliensis TaxID=1926277 RepID=UPI0009883A71 ---NTDDKFAQLEDDYNARLGVYAIDTGSNQTI-EYRSDERFAFASTYKALAAAILLQQKT ---MEELEKVITYTADDMVPYSPVTEKHMDTGMTLFELAEAAVRTSDNTAGNLLLNALGGP -DGFEEALRQAGDNITQSDRYETELNEFKPGDIRDTSTPKALATNLQAYAVSDMLSDEDRE -RFTNWLQGNATGDTLIRVGAPDGWTVGDKSGAGSYGTRNDIAVVWPPNREPIVMAIMSRH -NTEDAKYDDGLIAKAAKIALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037B1422 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADQRFAYGSTFKALAAAEVLDATT ---DAELDQVVWYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEAIPGDRRDTSTARALTEDLREYAVDDALDPTDRD -LLNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEADASFDNALIAEAAKVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007F11E8D --nDVQQKLAALEKSSGGRLGVALIDTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGREA--------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. QL37 TaxID=2093747 RepID=A0A2S6PH06_9ACTN ------PAFRELERKFDARVGVYAVDTGSGLSL-THRPDERFAYASTCKALLAGALLDRYT ---LQRLDRRVRYGPEELVANSPVTERHVDTGMTLRELCDTAVRYSDNAAANLLFHELGGP -RGLKDALLALGDRTTRCDRYEPDLSEAAPGDPRDTSTPRALAADLRAYVLGGTLGTDKRA -VLTDWLKRNTTGDALIRAGAPDGWVVGDKTGTGGYGTRNDIAVLWPPESAPIVLAVLTRG -NARGAEPQDPLVAQAARVALTAf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 4(2017) TaxID=1404402 RepID=UPI001408E54E -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKAPILIAAYTQG -GTPNAAQIEAVFARVGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. Nf4 TaxID=2116542 RepID=A0A2T3WUA6_9GAMM -----ASDFAALERACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNRFAEGDPRDTTTPAAMAGSLQRVVLGQVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLRA -GQISYEQQAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus velezensis TaxID=492670 RepID=UPI0012AB4E6D -----NQKFVQLEKKFDARLGVYAIDTGSNKTI-AYRPNERFAYASTYKVLAAAAVLKKSS ---NEKLNAIIRYSKDDLVTYSPITEKHMDTGMSLKEISEAAVRYSDNTAGNLLLQQLGGP -KGFEKSLKQIGDHVTKADRFETDLNSAIPGDRRDTSTAKALATDLKTFALGNTLTADKRT -ILTDWMRGNATGDELIRAGAPAGWEVGDKSGAGSYGTRNDIAIVW---RAPIVLAILSNR -FTEDANYNNALIAEAAKVALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=UPI000B9E62B9 ---DAARQLRDLEREHGARLGVFGWNTVTGASV-SHRGDERFPMCSTSKTPAVGAVLRDLD -HDGTFLSKIIHYTERDIERGAPVTGRNLAQGMSVADLCGAAISYSDNTAVNLLLAELGGP -TAVTRFCRSIKDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYARLALGNALAAADRK -LLTGWLLANTTGDKRLRAGLPGNWRVADKTGTGSYGTANDVGIAWPPGQGPIVLSVLTTR -PDADAEADDLLIARAATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces celluloflavus TaxID=58344 RepID=UPI000DA63C33 ---DAARQLRDLEREHGARLGVFGWNTVTGASV-SHRGDERFPMCSTSKTPAVGAVLRDLD -HDGTFLSKIIHYTERDIERGAPVTGRNLAQGMSVADLCGAAISYSDNTAVNLLLAELGGP -TAVTRFCRSIKDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYARLALGNALAAADRK -LLTGWLLANTTGDKRLRAGLPGNWRVADKTGTGSYGTANDVGIAWPPGQGPIVLSVLTTR -PDADAEADDLLIARAATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000EFC5438 --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0001E4C4B9 --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Kushneria konosiri TaxID=698828 RepID=UPI000A3AF19A --qKIQDRIQALEAQHGGRLGVALMNVGTGAVV-SHRGDERFLFNSTCKVVIAAALLAQVD -NDKASLDQRIEVKASDLTGWTPITEQKLGSPMTIAELCQAAVAWSDNAAANLLIERLGGP -ESVTAFLRNIGDATTRLDRTEPALNEDHQGDERDTTTPLAMMQTLQTLLLGDALSPSSRH -QLAAWMIEGKTGNARLRAGMPANWLIAEKTGTNSVGNAADIGLAWTPDRGAVIAIAYVYL -PEADKAQRDQVIADIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium symbiodeficiens TaxID=1404367 RepID=UPI00140FD866 -------ELETYERESGGRIGVYAENLTTGKKL-TWRADERFVMCSTFKASLAACVLARVD -RGEEKLAATIAYGKADLLEYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPTSRA -LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPKPETPILMAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A516R262_STRST ----YARAFKKLERKFDARLGVYAVDTGTGREV-AYNDSRRFAYNSTFKALAAAEVLRQYA ---PDRLDQVVKYSKDDLIANSPVTEKHVDTGMTLRALCDAAVRYSDNTAANLMFDKLGGP -KGLDAALERIGDDVTRMDRVEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDALAAPERT -QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPGAAPLVVAILSHR -GDKDAAPDDKLIAEAASVVA--- ->[subseq from] Beta-lactamase CTX-M-2 n=1 Tax=Xenorhabdus cabanillasii JM26 TaxID=1427517 RepID=W1ILU4_9GAMM ---QIINQLVALEKSANGHLGVFLINTADNSTI-GYRANERFPLCSTSKFMTASALLKKSE -KDGNLLNQRINYKQSDVVEYSPITEKHVESGMTLAELSAATLQYSDNTAMNLLLDQLDGP -RGLTKFARTIGDNEFRLDRKEPELNLVKPGDERDTSTPQATAKSLYKLTLGNVLATNQRV -QLVEWLKGNTTGDASIRAGVPKDWVVGDKTGLCDYGSTNDIAVIWPTNRAPLVLVTYFTQ -PGKNAKARRDVLAEATRILTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1114.5 TaxID=1938830 RepID=A0A495SSF0_9ACTN ---DTHRRLSALEQQHGARLGVFARNLSTGRTV-RYRAGELFPICSVFKTVAVAAVLRDLD -RDGKFLAKRIHYTEADIKRGAPVTGENLANGMTVAELCKAAIDHSDNTAGNLLLRELGGP -TAVTDFCRSIGDHVTRLDRWEPELNTAEPDRTTDTTSPQAIARTYRRLTLGHALPPAKRD -QLTTWLRGNTTSIHRFREGLPQDWALADKTGSGQYGTANDVGIAWTPSGAPVVLAVLTTK -PDEAAPKDEPLVAETAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Nitrincola nitratireducens TaxID=1229521 RepID=W9UVN9_9GAMM ---ALMTELQRIENVLDARIGFSAYDSETGVRW-EYNADQRFAMSSTFKTLACAALLQRVD -SNQEQLERTVSFSKSDLVTYSPITEQHADNRMSLFELCEATMTTSDNTAANLILQAMGGP -GVVTEFAREIGDNVTRLDRWETELNQATPGDDRDTTTPNAMVANLKGLLLGDVLSPNSKS -QLREWLVGNKVADGLFRASMPAEWIIADRTGAGGFGSRAITAVIWPPERLPIVVAFYITE -TTASFEDRNTAIAELGRVI---- ->[subseq from] class A beta-lactamase n=1 Tax=Gallaecimonas mangrovi TaxID=2291597 RepID=UPI000E1FEC27 ---SFADALSELEIQHGGRLGVAAFNSADGNRL-AYRADTRFAMCSTFKAVLAGAILQKVD -SGQLKQQSPVRYDASELLDYAPVTRLHLADGMTVAALAKAAVTLSDNTAANLLLKVIGGP -QALTAFYRQLGDSTSRLDRFEPSLNSNEPGDVRDTSTAAATLHSWRQLLLGKALLPASRQ -QLLRWLKDSQTGQDRIRAGLPQGWQVGDKTGSCENGGTNDIAIVWPANTPPYLLAIYYSD -GLGSSAQKNRVLAEVSRLVAKRf ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 2251 TaxID=2560053 RepID=A0A4Y5SSU7_9RHOB ---TVTEAARAIEADLGGRVGVSLRQPGGSDAT-GYREDERFPLSSTFKVPLCGTILTLVD -AGEDQLDRRVGYSPGDLVTYSPVTETR--DAMTVAELCEATITLSDNTAANLLLDRLGGP -EDFTQYLRAIGDDTTRLDRWETDLNEAVPGDPRDTSTPAAMTATLETLLFGPVLSVASQQ -QLEAWMRADQVADDLIRASLPEGWVIGDKTGAGGYGSRSIIAVIRPPQGDPWLTAVYLTG -NEADMPTRNRAIARIGAALVS-- ->[subseq from] Beta-lactamase n=1 Tax=Kushneria konosiri TaxID=698828 RepID=A0A2Z2HB39_9GAMM --qKIQDRIQALEAQHGGRLGVALMNVGTGAVV-SHRGDERFLFNSTCKVVIAAALLAQVD -NDKASLDQRIEVKASDLTGWTPITEQKLGSPMTIAELCQAAVAWSDNAAANLLIERLGGP -ESVTAFLRNIGDATTRLDRTEPALNEDHQGDERDTTTPLAMMQTLQTLLLGDALSPSSRH -QLAAWMIEGKTGNARLRAGMPANWLIAEKTGTNSVGNAADIGLAWTPDRGAVIAIAYVYL -PEADKAQRDQVIADIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodoligotrophos appendicifer TaxID=987056 RepID=UPI00117DF5D0 ---TMDDRLRDVEARNGGQLGVAILDLASGHVF-GHRADERFPLLSTVKLLAAAHVLARVD -RGQERLDRRVIFSKRDLVTYSPMTEGRVGAPMTMAELCDAAIATSDNTAGNLLLASAGGP -AGLTRFLRSIGDEVTGLTRIEPFLNSAVPGDLHDTTTPRAMLETMRKLLVDDGLSETSRR -QLAAWLVANKTGDKRIRAGIPKTWRVGDKTGTNQM-GACDVAIVWPPARKPILVTVYYAS -KPQTAESRDAVIAAVGRLVA--- ->[subseq from] class A beta-lactamase n=2 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=UPI000FFE44B7 ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVEQLGGP -DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=2 Tax=Serratia fonticola TaxID=47917 RepID=UPI0002604937 ------DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCSSFKGFLAAAVLSKSQ -QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP -EGMTSFMRSIGDNVFRLDRWALELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH -QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVAHAPIVLAVYTSK -PDRNSKHSDAVIADASRIVLESf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LaPpAH-199 TaxID=1265493 RepID=A0A1G6MLD6_9ACTN -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDQRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLDGALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia crassostreae TaxID=53428 RepID=UPI00082A6E6D ---AATSRFADLETKAGARLGVYALDTGSGHTV-SYREGERFPMASTFKGLACGGLLRDHS -LASGYFDQVIRYPASDLVEFSPETEKHVEDGMTVSALCDAAITLSDNTAGNQLLKLLGGP -AGFTAFLRSIGDDVSRLDRWETELNTAIPGDERDTNTAAALVSDYRKLVLGDLLGQAERK -RLQDWLIASTTGGKRIRAAMPGHWVVGDKTGSPAYGSALDVAIAWPPNSAPIVIAVLTTK -PQQDAKPDNDLVADAARVALETf ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium kowhaii TaxID=1300272 RepID=A0A2W7DSD9_9RHIZ -------KMRRIEVKSGGRLGVACRISGTTAQF-GYREDEPFPMCSTFKALAAAFVLHRVD -GGIEQLDRSIEVPHDAIIANSPTTNKHAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP -PQLTAYLRSIGDKVTRLDRIEPELNESLPGDARDTTSPLAMVNNLERLTIGNSLSGKGRA -QLVDWLVANKTGDARIRAALPKGWTCGDKTGTGARGSTNDAAVIWPTSSNPILMSIYLTG -TKQSLAKRNAVIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax delafieldii TaxID=47920 RepID=UPI00076AB79B ---AWNEALASIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDPITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSRTANDIGVLWPQGGAPVLVTCYLTR -STASGEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0003A66027 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAVADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00039F9936 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAVADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI000D9214D4 ---AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA ---PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP -AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA -LLVDLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH -DTADAEPDDALVAAATRTAL--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudovibrio axinellae TaxID=989403 RepID=A0A165SXE3_9RHOB ---QLLETVAKLEADVGGRIGVVVRHTGSDWSI-EHRPNERFPMASTFKALLCGGVLARVD -QGQENLENVARYTADELVRYSPVTEKHVATGMSVGDLCEATITVSDNSAANFLLKRLGGP -EGFTRFMRGIGDEDTRLDRWEVEMSESKPGDLRDTTTPEAISKSLGKLLFGDILQPHSRE -LLTHWMINNKVADALMRKHLPTGWRIADRSGMGHYGTRGNIAALWTETGEVYLAAIYMTG -SDADVKTRNATIAEVGQAIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0004764019 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAVADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=Q59923_STRLA ---RVARALAELEREHGARLGVYALETDTGRTV-THRADELFPMCSVFKTLAAAAVLRDLD -HDGSVLARRIHYTQADIDRYSEWTKRHLANGLTIGELCEVSITYSDNTAANLLLRELGGP -AAVTRFARSLGDPVTRLDRWEPELNSAEPDRVTDVTTPRAIARTYARLVLGDGLGRADRG -LLTGWLCANTTSGARFRKGLPAEWRLGDKTGGGSYGTNNDVGIAWRPHGAPLVLAVLTTK -PAQDAKADDALVSGTARALAGAf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVU4_9BACT ------EAARQAEAQLDARVGLAVYDTGSGANW-LFNADGSFPMGSTFKVLACGVLLARAD -AGDEDLDRFVEIVQTDLVTYSPVTETWVGRNVSLGEICAATMRTSDNTAANKVLEALGGP -GSLTAFLRSLGDQTTRLDRWETDLNEGTPGDPRDTTSPAAMAASFQKFVLGDVLSTSSRE -TLTDWLLGNEVGGPLLRAGLPEDWRIGDRTGAGGHGSRGIVAVLWPPGRAPLIAAIYLTE -TQATLEGRDAAIAAIGRAIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea sp. FXJ1.1311 TaxID=2591470 RepID=A0A563EGR9_9PSEU ------DRLAELERKFDARLGVYVLDTGSGATI-VHRPDERFAFCSTFKGVAAAAVLHRNP ---LSHLDTVVRYTEADLMEHVPVTGQHVATGMKIRDLCDAAIRHSDGTAGNLLVRDLGGP -AQLTDFVRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTTYQKIVLGPTLPDDKRA -FLRDLLERNTTGDQRIRAGVPQGWVVADKTGTGSYGTLNDIAVVWPPNAAPLIISIMSSK -AAKGAKADQAVIAEAAARVV--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A4U3GH03_9GAMM ---STARDFATLEAASGGRLGVTLLNTGSGQRI-GHRQDERFPMCSTFKFALCATVLRLAD -QGKLSLDRRLAMTTQDLLSHAPVTARHVGKDVTVRDLCRATMVTSDNPAANLLLRVVGGP -AGVTAFLRASGDDVTRNDRYEPEVNRFAPGDPRDTTSPAAMAASLQRLVLGELLQPASRQ -QLADWLIDNETGDAHLRAGLSNAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ARLDGAGRNDVLRQVAVIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis quinghaiensis TaxID=464995 RepID=UPI00123AF155 ----MDSEFAHLEEEFDARLGVYALDTGTDRAV-GFQADERFAYCSTFKVLAFGAVLDRTP ---VDELDRVVTFSGADLVFHSPVTREHVSTGMTLREIGDAALRHSDNTASNLLFEELGGP -QGLDEALREIGDDVTSVDRIAPEMAEAVPGDVRDTSTPRAMATSLREFALGDVLSEDKRG -VLVEMMRANTTGDDLIRAGVPEGWEVGDKTGACGYGTRHDIGVLWPPEGAPIVLAVMSGR -DEAGAEYDDALIARATEMVV--- ->[subseq from] Beta-lactamase n=1 Tax=Thalassobacillus cyri TaxID=571932 RepID=A0A1H4G6Q8_9BACI ----TDKEFTQLEREFDARIGVYAMDTGTDQTV-EYCPDEHYAYSSTFKVLAAAILLKQND ---IEKLKKIVTYTKDDLVTYSPVTEKHVDTGMTMLEISEAAIRTSDNTAGNLLLEAIGGP -EQFKQALRDMGDDVTMPERYETELNEFTPGNKRDTSTPRVIATNLEKVALGDFLPDDKRE -LLIDWMKGNQTGDSLIRAGAPQGWRVDDKSGAGSYGTRNDIAVVWPPNREPIVIAVMTRY -DTKNAEYDDSLVARAAEITLD-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas campestris pv. campestris TaxID=340 RepID=O87643_XANCE ---MLRARWAEIQRGTGGRLGTCLLDSGSGWRI-GQRENERFPMCSTFKFVLAAAVLQRVD -KGELRLTQQIKIRASDMLEHAPVTERHVGGSLSVAELCQATMIHSDNPAANLLFPLIGDP -PGLTRFLRGIGDTKTRSDRLE-AMNGFAPGEPRDTTTPAAMAATLRTLLLGDALQPASRK -QLTAWMIDNRTGDDCLRAGLPRDWKIGDKTGSNGTDTRNDIAIIWPPGRAPLLLTAYLNG -ATVDAAARDAALKAVAEAVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID3343 TaxID=2690260 RepID=UPI00136ACC65 ------GQLSEIERQHGARLGVFACNTATGATV-AYRAGERFPMCSVFKATAAAAVLRDLD -RDGEGLARRIRYGDKDVADYAPITSRNLAGGMIVADLCAAAIAYSDNAAANLLLRELGGP -AAITRFCRSVGDGTTRLDRWEPALNSAEPWRATDTTSPRAIGRTFARLTLGDALAPSDRK -RLTGWLLANTTGDARLRAGLPAGWALADKTGTGGFGTTNDVGIAWTPNSTPIVLAALSTK -QDADAPADEPLMAKVAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Sinobacteraceae bacterium TaxID=1969813 RepID=A0A522ZKT7_9GAMM ---DYAAQLAELERVHGGRLGVAILDTGNGRYI-AHRADERFLMCSTFKLLLAAAVLARVD -HGVEELDRRVMFDKATLLDWSPVTQLYAGPPMTVAALCQAAITMSDNTAANLLLASSGGP -AAVTRYARSLGDTLTRLDRSEPTLNHA--DGEKDTTTPRAMLGDIHKLLLGDALAASSRG -QLVDWLQHCQTGAASLRAGLPADWRTGDKTGSGV-AATNDVAILWPPARKPLLVTAYYDN -GQLPASERRAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora purpeofusca TaxID=67352 RepID=UPI0007C4CD52 ---ELADRFRALERSHSARLGVFAQDTVTGRTV-AHRADELFPMCSTFKTIAVAAVLRDLD -RDGTFLAQRRLYTATDVAQYAPITGLNLEAGLTVEELCAAAIRYSDNAAANLLLRELGGP -DALTRFCRSIGDRVTRLDRWEPALNSAEPSRLTDTSSPHALGRTYARLALGATLDPADRQ -RLTGWLLTNTTGTNRLRAGLPPTWHVAEKTGTGSYGTTNDVGVTWRPDGRPIVVAVLSTK -HTADAPADEPLIAETARIVAT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI96-02 TaxID=1522760 RepID=A0A3N6ETQ7_9ACTN ------RAFRALEAKYGARLGVHAVDTGSGRVV-AHRDRERFAYASTFKALAAGAVLRKHG ---LEGLERTVRYGREDLVDYSPVTEKHVDTGMSLGDVCDAAVRYSDNTAGNLMFDALGGP -RGLQAMLAELGDDVTRMERRETELNEWAPGAIRDTSTPGALAGSLRAFVLGDALEGPERA -RLTTWLRTNTTGGELIRAGVPKDWVVGDKTGAGSYGTRNDIAVVWPPGAAPLVVAVLSNR -GTADAAYDNALIADAAAVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus dictyosporus TaxID=1523247 RepID=UPI000B807880 ---DVSAEFAALEARFDARLGVFAVDTGSGAIL-EHRADERFAYASTIKALAAGALLTRTS ---PADLQRPVPVTPADLTTYSPVTETRVGGSMTLAELCDAAVRFSDNTALNLLLRELGGP -AGLDAALEAIGDDVTEVARTEPELNSAVPGETRDTTTPRALAGSLRAYAVGPGITEEDRA -QLLDWLRRNTTGDALIRAGVPADWDVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR -DEPDADPDDALVAEAARVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI000F62A280 -----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD -RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP -AALTAFLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLGRCVAGAVLAPASRL -QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG -SRVDSAARDAVLARAGQLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces iranensis TaxID=576784 RepID=A0A061A8X6_9ACTN ---AATGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALAAGAVLRKYK ---LSGLDRVIRYSKDDLVDYSPVTEKHVDTGMSLGALCDAAVRYSDNAAANLLLDELGGP -KGLDATLEKLGDDVIQMENIEPELSRWVPGETHDTSTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGNGSYGARNDIAVVWRPDAAPLVVAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora endolithica TaxID=230091 RepID=A0A3A9ZJY6_9ACTN -------DFTPLEAEFDARLGVYAVDTGTGRTV-AHRADERFAYASTFKALAAAAVLDATT ---TAELDEVVTFTRADLVAFSPVTGRHVDSGMTLRAVADAAVRHSDNTAGNLLLDRLGGP -AGFERDLRELGDEVTEPARRETALNEAAPGDVRDTSTPRALATTLRAYAVGDALDVGDRA -VLVDWLRRNTTGAKLIRAGAPDGWVVGDKTGTGGYGTRNDIAVLWPPDRAPIVLAVLSRR -DARDADHDDALVARAAEVTL--- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=UPI00098844BB -----EEAFKELEDEFDARLGVYAIDTGSEQTV-TYRSDERFAYASTFKALAAGAILQTNS ---IEDLEKVITYSEEDLVTYSPVTEKHAGDGMKLEEIIEAAVRYSDNTAGNLMLEELGGP -DGLEGILRKNGDETIEMDRMETELNEAVPGDKRDTSTPQALAESLQKYVLSDLLPEDKRE -LLIDWITGNEAGDSLIRAGVPEGWEVGDKSGAGSYGTRNDIAVVWPPDNAPIVIAVLSSQ -DTVDADYHDELIEKAAERVME-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rhizosphaerae TaxID=2053003 RepID=A0A558CTQ5_9PSEU -----QQDFERLERTFGARLGVYAVDTGTGREV-AFRAGERFAYASTHKVFSAGAILQRTP ---VEGLDRTVMFGQGDVVSYSPITQKYAGTGMPLRAVLDAALRYSDNTAANLMFRELGGP -AGLTDALRAIGDTTTSPDRIEPALNEAVPGDPRDTSTPRAMAADLRAFTLGTALPEDRRA -VLVGMMRANTTGATLIRAGVPADWQVADKTGAASYGTRNDIAVVWPPQRAPIVLVVLSDR -QAKDAAYDDKLIAQAATSAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CA-128772 TaxID=2073159 RepID=UPI000CD10927 ------PDFAPLERDFDARLGVYALDTGSGREL-THRADERFGYASTHKVFSAAAVLQRTG ---LDGLAKNLTYTRADLQPNSPVTEKHVATGIPLRDAIDAALRYSDNTAANLLFRELGGP -AGLAQALRGIGDTTTYVDRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFTLGAALPPEKRT -VLTDMMRANTTGAALIRAGAPAGWAVADKTGTGSYATRNDIAVVWPPGRAPIVLVVMSSR -PAKDADHDDRLIAQAAKLVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) TaxID=926566 RepID=I3ZLG6_TERRK ---ALPTAIAAMEKKNGGRIGVSLLDTATGERA-AWRADERFPMCSTFKFLLAAAVLHRVD -TLKDDLRRQVDVPPKPLLGNSPLTAEHAGTSMTLGALCSAILIRSDNTAANVLLETIGGP -GKITTYAQSLGDTVTRLDRTETALNESLAGDPRDTTSPDAMVHNLQSLLLGDALKPDSRQ -QLLDWMQSSTTGLTRIRAKLPKGWRAADRTGSNGEHTTNNIAVLWPNGGAPLIVAAYITQ -CPGSEDKRNAMLAEIGRLVAA-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DA98378 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YC537 TaxID=1775135 RepID=UPI001378DA9C ----YSRELKALERKFDARLGVYAIDTGTGREV-AYNDKERFLFASTFKALAAAAVLDKHS ---DRDMERVVTYDKSDLVENSPVAEKHVDSGMTLNELCDAAVRYSDNTAANLLFEDLGGP -RALDATLAGLGDDVTRMERIEPDLSDWEPGNDRDTSSPRALAADLRAYVLGDALDRGDRD -RLTKWLRTNTTGGALIRAGMPKGWTVGDKTGMGNYGIRNDIAVVWRPDAAPLVVAVLTNR -HKPGDKHDDKLIADAAEVVAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8I7B1_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI000BAA9A6A --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP -EQVSQFVRSLDDKVTRLDRFEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TLI_185 TaxID=2485151 RepID=UPI000F51558F --aAAVDRLRELEQQHGARLGVFAHNVRTKQTV-EHRADELFPVCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP -TAITRFARSIGDPVTRLDRWETDLNSAEPWRITDTTTPRAIGRSYARLVLGHVLDRRDRA -LLTHWLLGNTTSGNRFRAGLPKTWTVADKTGGGSYGANNNVGIAWTPDGTPIVLAVQVTK -PDQDAELDNPLIAGTAAFLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium durans TaxID=2202825 RepID=A0A2U8WEG0_9RHIZ -----RQSLRVIEDRLGGRLGVAVRDTSSGRAL-LHRADARFPMCSTFKVLAAAAILARVD -AGRERLERTMPFTAADLDSHAPVTK-EAGGEMSLADLCAAAVVWSDNTAANLMLQALGGP -PALTAWLRGIGDQTSRLDRTEPTLNTAIPGDPRDTTSPAAIAEDLERLLIGDVLSPASRG -RLEGWMVAARTGLKRLRAGLPQDWAVGDKTGSGDNATANVVAILRPPGRAPLVAAIYLTG -SISTAEERDAAHAEIGRLVAVTf ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter capsici TaxID=435897 RepID=A0A291A5M4_9GAMM ----WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE -LGKVALSQQVPITAADMISHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP -QGLNRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ -QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPLLIVSYLAT -TKLDGAGRDAVLASLARIASEHf ->[subseq from] Class A beta-lactamase n=1 Tax=Labrenzia sp. VG12 TaxID=2021862 RepID=A0A222F0Q1_9RHOB --------VLDAEKRLSARVGVSVIDLETGTRW-QNRADERFPTNSTFKTFLCAAFLDAGA -RGAVDPDRAIVIRQSDIVSYSPVAKEKVDGAVTLRELCATTVTISDNAAANLVMKELGGP -EAVTAYLRSIGDEVTRVDRWEPDSNSGIPGDARDTTSPNAAAETLKKLVLEETLPDAERR -LLTKWLVGNKVGDATLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPVVIAIYITQ -TAASFKARNAAIADIGQALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. SUTN9-2 TaxID=1167456 RepID=UPI000D65C147 ------SEFESYERESGGRIGLYAENLATGKKL-SWRADERFVMCSTFKASLAASVLARVD -RGEEQLAAMIRYGQSDLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVAGEALSPASWA -LLTDWMVNCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPSAAQITSAFARIGRMVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID13031 TaxID=2706046 RepID=A0A6B2U1K9_9ACTN ---QVTEPFSKLEKQYSARLGVFAYDTGTHRTV-SYRAGERFPHASTFKALACGVLLIETK -----NLDKLIRYDESILLPNSPITEKHVATGMTLRELCDAAIRYSDNAAANLILAEIGGP -SGLQRALRRLGDVVTNTSRTEPTLNEATPGDTRDTTTPRALATSLQKLTLGHALPPAKRA -VLVGWLKANTTGGTTIRAGVPKDWTVGDKTGTAAYGGRNDVAILWPPNRAPIMLAILSTK -GAKDAVPNDALIAAAAAAAIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24051 TaxID=1463832 RepID=UPI0004C8C8FD ------RAFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Gammaproteobacteria bacterium DM2 TaxID=2169539 RepID=UPI000D3E8B69 ---PLQKEFASLEQSAHGRLGIYAINTGNAQEL-GYRADERFPLASTFKVIAVSDLLQKSV -TAPELMQHKVNFNKKDLVNYSPITGKHLESGMTYAELSAAALQYSDNTAGNLIVKQLGGP -SEVTLYARQIDDQEFYLERWETELNSATPGDVRDTTTPKAMAITLKRLAFKDVLPKAQRR -QLLEWMKGNTTGDASIRAGLPHGWTVADKTGGGSYGSTNDIAVIWPKRKAPWVIAIYFTQ -SKQDAPLRKDVIAAATRLIVKQw ->[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6B1L8F4_9ACTN -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. S501 TaxID=2420135 RepID=A0A4V1B2K8_9ACTN -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-325 TaxID=1463899 RepID=UPI00056D076B -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] Beta-lactamase n=2 Tax=Gracilibacillus orientalis TaxID=334253 RepID=A0A1I4JZW9_9BACI -----DEEFAQVENEFDAQLGIYAIDTGKNQIV-EYNPDERFAYSSTFKVLAAAILLKQNE ---IEELEKVVTYSEDDLVTYSPVTEKHVDTGMTLLEVSEAAIRKSDNTAGNLLLEALGGP -DKFEQALRDIGDDITEPERYETELNEFTPGSKSDTSTPRAMATNLKKVALGDFLPSNKRD -LLVEWMKGNATGDALIRAGQPEGWIVGDKSGAGSYGTRNDIAIVWPPNRAPIVIAVMSKH -DSKDAEFNNELVAKAAEITL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. DJ TaxID=2067551 RepID=A0A2N5XF65_9ACTN ----TAAQLRRLEARHRARIGAFAHNLATGATV-LHRAHDRFPLCSVFKPLAAAAVLRDLD -RDGEVLAERIRYTEADVVADSPVTDEHLATGMTVGELCDAAVRHSDNTAGNLLLRRLGGP -SAVTRFCRSTGDTVTRLDRWEPELNSAEPWRVEDTTTPYAIARTYARLVVGDVLEPRDRE -RLTHWLLTNTTNEARFRAGLPEDWSVADKTGAGEYGTCNDVGVARTPEGVPVVLAVLTRK -GEADAKPDNPLVAETAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Mixta gaviniae TaxID=665914 RepID=A0A1X1DG72_9GAMM -haALTQQLAALEKSAGGRLGVAWIDT-DGARY-GYRADERFPMTSTFKTLAVAAILHNSI -AQPGLLEKKIPIREADRVTWTPVTGHYFGKEMSIAALCAAAIEYSDNLAANYLLQELGGP -QGVTAYARSLGDTLTRLDRREPALNSAQPGDLRDTSTPAAMAANLQTLTLGKALPTAQRQ -RLISWLKQNTTGDQSIRAGVPAGWTVGDKTGAGAWGATNDLAILWPEKGAPKILAVYFIQ -SQADAANNKAVLASATRQVI--- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=X0PTB1_9NOCA -hrSLDATIDALEAQYSTRIGVAAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVVEPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDIGDESTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPVVLTILTDS -LTEDAQGNNQAIADTTAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia pseudobrasiliensis TaxID=45979 RepID=A0A370I5N8_9NOCA ----SDQRFGELERKYGARLGVFAID-SDGKRV-GYRQDERFAFDSTFKTLVCGTLLREHP -LATGYFEQVVHYTREDVVKYSPVTETRIDTGMSVAELCEAAITKSDNTAGNQLLKLVGGP -EALTKALRTLGDSVTRSDRWETELNTSIPGDERDTTTPAAIGNDYRALLTGEALGAPERD -RLKSWLVANTTGGQRIRAGVPKEWTVGDKTGTGDYGSANDVAVAWTERGTPVVISILSVK -SDQQAQADNALLADAARIVVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=A0A124HI64_9ACTN ---DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD -RDGEVLARRIHYTKDDLVIGSDQTAAHLAEGMTIAELAEVAITHSDNAAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM -PAPDAVRDDALVADAARAVAD-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI001020260B ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 8K308 TaxID=2530388 RepID=A0A4R4PLF5_9ACTN ----VTRGFEALEREFDARLGVYVLDTGTGREI-AYRADERFAYASTFKALAAGAVLHEYG ---LDGIDEVVTYTEDDLVDHSPVTEDFVETGMSLSELCAATLWYSDNTAGNLLFDALGGP -DGLEAILEELGDDVTEMDRYETELNEATPGDIRDTSTPRALASDLREFLLGDVLDARERE -LLRMWMVTNTTGETLIQAGLPDDWTVADKSGAGGYGGRNDIAVVWPDDGDPLVMAIMSAH -DEADAQRDDALIAEAAAVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1813 TaxID=1463888 RepID=UPI0004CA2A07 ------EALRRLEHTHRARVGAFAHNTATGATV-AYRAHTPVPLCSVFKPLAVAAVLRDLD -RNGETLARRVHYTDADLVENSPATEKHVATGMTIAELCAAAVRRSDNTAGNLLLRELGGP -TAVTAFARSLGDRTTRLDRWEPELNSAEPWRRTDTTSPAAIGRTYARLLVGDALSPSDRG -LLTAWMKTNETNTERFRAALGKDWAIADKTGSGSYGTGNDVGVAWTPDGIPIVLAVLTGK -PEQAAAYDNPLIVDVTKVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-237 TaxID=1463895 RepID=UPI00099DFCE1 --------LRALEREYGARLGVYALDTASGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD -HDGAHLAKRIHYTLQDVTDGGSITEKNIASGLTVAELCSAAIAQSDNTAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIGRTYARLALGDALDPGDRE -RLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLVLAILSTM -PEPTAPRDNTLIARTAKLLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudovibrio stylochi TaxID=1807766 RepID=UPI00082B0C2F ---ELLDTVRKLENEIGGRIGVTLQHPKSAWSI-DYRSNERFPLSSTFKPLVCGAILARVD -RHEDSLEKIITYKKEQLVAYSPVTKENVSSGMSIGQLCEATITLSDNSAGNFLLKHIGGP -EKLTAFLRGIGDARTRLDRWETKLNEGKPKDPRDTTTPNSIARTLNKLLLTDVLKPKSRQ -QLKQWMLDDKVADALIRKHLPTGWRIADKTGAGGYGSRGIIAAIWPKAAEPYFTAIYMTG -SNADIKQRNAVIAEIGRSII--- ->[subseq from] BIC-1 class A carbapenemase n=1 Tax=Pseudomonas fluorescens TaxID=294 RepID=D2WFL1_PSEFL -----RQKIVKLEKDFGGRIGVSAIDTGANRTF-DFRADERFPLCSSFKGFLAGAVLSHSQ -QQEGLLEKRIDYKNRVMEPHSPISAQHSSTGMTVAQLAAAALQYSDNGATNLLLENLGGP -AGMTTFMRTLGDTTFRLDRWELELNSAIPGDDRDTSTPHAIARSLQKIALGEALQTAPRQ -QLVDWLIGNTTGGARIRAGVPVEWVVGDKTGTCGYGTANDYAVIWPKTSAPIVLAIYTAK -PNKEDKHSDAVIAEVTRAVLESf ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_044 TaxID=2175628 RepID=UPI000DA7E7FA ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -RAVERWLRGIGDRTTRVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRDPVVLVVMTSR -SDPGAESSDALVAAATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium stylosanthis TaxID=1803665 RepID=UPI0007C519CF -------ELETYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAVIPYGQADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSQASRV -QLTDWMVNCKTGANRLRGGLPSSWTIGDKTGNNGKDASGDIAVVWPKPDAPILIAAYTQG -GSPTAPQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Frankia canadensis TaxID=1836972 RepID=A0A2I2KKI0_9ACTN --------LVDLERRYGARLGVFAIDTASGRSV-RHRENESFALCSTFKTYAVAAVLRAHP -LRGGDLSRTIHFSAADIVANSPVTSTRVATGMTVAELCDAAITHSDNTAGNQLLKLLGGP -AAITRFARSLGDQSTRLDRWEPDLNSATRGDPRDTTTPLAIATGYRALLLGDALPAPERA -QLKTWLIANTTGTTRLRAGLPSSWTTGDKTGAGRFATLNDVAITWPDAGGPLVMAVLSDR -PEETATAADSLLAETARAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A3S3G490_9RHIZ --qAIEAKLAKLEGRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEQLDRRIVFSTDALVFFSPVTETRVGGDMSVAELCMATLTQSDNTAANLLLESFGGP -AALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGNVLSRASRA -QLAGWMIMNKTGDSRLRAGMPETWMIADKTGGNGHGNNNDIAVAWTPDQGAIVVATYCEI -PTISADQRNAVVAEVGRIVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V779_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter salarius TaxID=1420917 RepID=A0A1W6K516_9ALTE ----LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD -NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIDGP -DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD -TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ -TDASFDERNGAIRDLGGAIVKHf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium daqingense TaxID=993502 RepID=A0A562L1E2_9BRAD -------EFEAYERESGGRIGLHAENLASGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYREADLLEYAPVARQNLAAGMSVSEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSRPGDPRDTTTPAAMAGNLRRLVLGAALSPASRA -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDIAVVWPKPDTPILITTYVQG -GTPSAAQIAAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Plasticicumulans acidivorans TaxID=886464 RepID=A0A317MVF0_9GAMM -------RLAVLEGTLEARLGVAVLDTHSGELR-GRRLDERFPLCSTFKLIACGALLARVE -AAALDLVQPVAIRAEDIVSHSPLTGPRVGGTMRFAELCAAALTQSDNTAGNLILRAIGGP -AGLTAYVRALGDTQTRLDRWETALNAATPGDVRDTTTPAAMARLLHTLLLGERLAPAART -RLIEWLLANRTGDAKLRAGLPPGWRIGDKTGGGEYGTSNDVAIIWPGQGPALIVCVYLTQ -STASFAARDHAIAEVARMLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A4Y3Z210_BRAJP -------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMVGCKTGANRLRAGLPAGWKIGDKTGNNGKDASGDIAVAWPKNKVPILIAAYTQG -GTPNAAQIEAAFARVGRMVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Actinocrispum wychmicini TaxID=1213861 RepID=A0A4R2JKB4_9PSEU -------DFGRLERDFDARLGVYAVDTANGREV-AFRADERFAYASTHKVFTAGAVLQRIP ---IGDLERTVKYSQNDLVANSPVSEKQVATGMTLRAAMDAAIRYSDNTADNLLFRELGGP -NGLAAAVRATGDTTTHVDRIEPALNDTAPGDIRDTSTPRAMTATMRAFTLGNALPEDKRT -ILVDLMRANQTGGTVIRAGVPAGWQVGDKTGTGGYGTRNDIALVWPPQRAPILLAILSDK -KAKDAKTDDKLIAQAAAAALAAf ->[subseq from] Beta-lactamase n=1 Tax=Nocardia neocaledoniensis TaxID=236511 RepID=A0A317NUX6_9NOCA -------SFADLESKYGARLGLMVIDTGSGRTV-GYREGELFPMASTFKGLACGVLLQAHP -LDTGYFDQVVHYTAADIVANSPETEKHVDSGMTVAALCDAAITQSDNTAGNMLLRLLGGP -AGFTDSLRRLGDPVSRLDRWETELNTAIPGDVRDTTTAAALAADYRALVLGDALREPERA -RLATWLKASRTGAKRIKAGLPADWTVGDKTGTPAYGSALDVAIAWPPNRAPLVLAVLTTK -PDQNAEPSNELVAEATKAALA-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_050 TaxID=2175664 RepID=UPI000D92FB59 ---AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA ---PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP -AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA -LLVDLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTRH -DTTDAEPDDALVAAATRAA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEZ0_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus nigrescens TaxID=1070870 RepID=A0A1M5JPJ4_9ACTN ----VAGDLAALEARFDARLGVFAVDTGSGATL-EHRADERFAYASTIKALAAGALLARTS ---PADLQRPVPVTPADLTTYSPVTETRVGGSMTLAELCDAAVRSSDNTALNLLLRELGGP -AGLDAALEAIGDDVTEVARTEPELNSAVPGDPRDTTTPRALAGSLRAYAVGPRIAEEDRA -HLLDWLRRNTTGDALVRAGVPADWDVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR -DEPDAGHDDALIAEAARVVV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX5_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces formicae TaxID=1616117 RepID=A0A291QN41_9ACTN ------ARLKALERKHDARLGVYALATGTGATL-AHRADERFAFCSTFKTLAAAAVLARNP ---LSHLDRRVTFTRAQVNSISPVTEDHIATGMTIKQLCDAAVRHSDGTAGNLLMRDLGGP -ARLTDYLRDLGDTVSRMDQYEPELNRARPKDPRDTTTPRAVAADYQKLVLGDALPAAKRT -LLKDWLERGVTGDKRIRAGLPKGWTVAEKTGTGVYGRANDIGIAWPGTGAPLVIAVMSDR -SGYDARPKDAMIAEATAEIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=UPI000371978D ---DVTARLRALEKRYDARLGVFAHHVTTGRSV-RHRADELFPMCSVFKALAAAAVLRDLD -RDGEVLARRIHYTEADLVIGSDRTAAHLAEGMTIAELADVAITYSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRR -LLTHWLLNNTTSVNRFHAGLPKSWTIADKTGSGSYGTANDVGVTWTDAGDPIVLSVLSTM -PAQDAVRDDALVADAAAVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia xishanensis TaxID=238964 RepID=UPI00082DB233 -----HERLVELERQFDARLGVYALATGTGVTI-AHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVSYTEADLLKSASITSRHVATGMTIRDLCDAAVRFSDGTAGNLLLRDLGGP -AELTAYVRSLGDTVTRMDRIEPAITEATPGDPRDTTSPRALGTDYQRLVLGDALPADKRA -FLRDLLERNATGAQRIRAGVPQDWTVADKTGTGDYGTLNDIGIVWPPASAPLVIALMSSK -TTVDAPYDQALLAEAAAYVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00128F4570 ----------------------------------SFRPEERFPMMRTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00035CFF1E -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPVTEQHLAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARCETALNEATPGDRRDTSTARALAEDLREYAVDDALEPADRD -ILNAWLRGNTTGGALIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDDALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=A0A542XUY9_9ACTN -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPVTEQHLAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARCETALNEATPGDRRDTSTARALAEDLREYAVDDALEPADRD -ILNAWLRGNTTGGALIRAGVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDDALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA204 TaxID=1289387 RepID=UPI000684DD29 --dKLHPQLAALERKFDARLGVYALGTGTGETV-VHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVTYDEDDLMKHSPVTGRHVASGMTIRELCDAAVRHSDGTAGNLLLRDLGGP -GRLTAYARSLGDKVTRMDRTEPAITEAAPGDPRDTTSPRAFGTDYRKIVLGDALPSGKRG -FLRDLLERNTTGARRIRAGVPASWKVADKTGTGDHGTLNDIAVAWPPRSPPLVIAIMSSR -DSKDAPYDEDLIAEAAAYV---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A3D9QYL8_9NOCA -hrSLDATIDALEAQYSTRIGVAAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVVEPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDIGDESTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPVVLTILTDS -LTEDAQGNNQAIADTTAAVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia neocaledoniensis TaxID=236511 RepID=UPI000D70F8BD -------SFADLESKYGARLGLMVIDTGSGRTV-GYREGELFPMASTFKGLACGVLLQAHP -LDTGYFDQVVHYTAADIVANSPETEKHVDSGMTVAALCDAAITQSDNTAGNMLLRLLGGP -AGFTDSLRRLGDPVSRLDRWETELNTAIPGDVRDTTTAAALAADYRALVLGDALREPERA -RLATWLKASRTGAKRIKAGLPADWTVGDKTGTPAYGSALDVAIAWPPNRAPLVLAVLTTK -PDQNAEPSNELVAEATKAALA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB58_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=UPI0009A0A89B ---DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD -RDGEVLARRIHYTKDDLVIGSDQTAAHLAEGMTIAELAEVAITHSDNAAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM -PAPDAVRDDALVADAARAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Simplicispira lacusdiani TaxID=2213010 RepID=UPI000E7152DC ---QWAETLAGIERTVQGRLGVAMLDTGTGLAL-GWRQDERFAMASTFKLALAGWMLALVD -QGRERLDARVFYGREALVAYSPATASRADEGLTVGELCAATVSLSDNTAANLLLARHGGP -AAFTAFVRSLGDGVTRLDRNEPTLNEAAVGDPRDTTTPQAMLQTMRKLVLGDALTPASRT -WLQRWLVETSTGDKRLRAGVP-GWRVGDKTGTASSGTANDIGVLWPPGGAPVLVVCYLTR -STAAPGQRDAAIADVARAVVA-- ->[subseq from] Beta-lactamase n=8 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB53_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces fradiae TaxID=1906 RepID=BLAC_STRFR ---RVEGRLRALERTHDARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD -RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLRDLGGP -TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE -RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR -FTPDAEADNVLVAEAARLLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium rifense TaxID=515499 RepID=A0A5D3K3U5_9BRAD -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEKLAAMISYGKTDLLEYAPVAKQNLSAGMSVADMCKASVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPVAMAGNLKRLVTGEALSPASRA -QLTDWMVGCKTGANRLRGGLPAAWKIGDKTGNNGKDASGDIAIAWAKPDAPILIAAYTQG -GTPNPTQIEAVFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=UPI000B8ABD97 ------AEFAELEDRFGVRLGVYAYDTGNATVV-AHRPDERFPMCSTFKALLGAAILHETS ---TVELDRHFTWSADDLLHHSPITEQHVASGLSAEQLCDAAVRYSDNTAANLLLNEIGGP -AGFTSFVRAIGDETTRLDRVEPDLSTGEPGDERDTTTPRAFADTLRSLVLGDALAPERQE -ILTEWLLTNVTGANRIRAGTPAGWRVGNKTGSGGYGTVNDTAVLWPPDRAPILLTVYTTI -GVRYAEYDEAVIAEAASIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=A0A221W5L2_9PSEU ------AEFAELEDRFGVRLGVYAYDTGNATVV-AHRPDERFPMCSTFKALLGAAILHETS ---TVELDRHFTWSADDLLHHSPITEQHVASGLSAEQLCDAAVRYSDNTAANLLLNEIGGP -AGFTSFVRAIGDETTRLDRVEPDLSTGEPGDERDTTTPRAFADTLRSLVLGDALAPERQE -ILTEWLLTNVTGANRIRAGTPAGWRVGNKTGSGGYGTVNDTAVLWPPDRAPILLTVYTTI -GVRYAEYDEAVIAEAASIAL--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBL7_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAINYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI001320C001 ----ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALEKPVKYGKADLLDYAPVAREHVERGMTVDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDDASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAETf ->[subseq from] class A beta-lactamase n=1 Tax=Terriglobus sp. TAA 43 TaxID=278961 RepID=UPI000645EEB5 --qRLPQQVATLEKDNGGRIGVYALDTGNGKSA-GIREDERFPMCSTFKFLLAAAVLKLVD -DGKQSLDQPLPIPNKPLIGHSPLTEPHAGATMPIAALCNAILNQSDNTAANVLLEAIGGP -PAITAFAHTIGDESTRLDRNEPDLNTSIDGDPRDTTTPVAMAKNLQRVLFGNALKPASRR -QITEWMENSLTGLERLRKDMPEGWRAADKTGSNGEHTTNDIAVLWPMRRPPVIVTCYITQ -CPGPETKRGAMIAEIGRFVR--- ->[subseq from] Beta-lactamase (Fragment) n=6 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBT2_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium loti TaxID=381 RepID=A0A2N5AXH8_RHILI ---EAENKLAELERKHPGRFCVTILDLGSGKRI-QHRADERILMCSTFKALLAALVLARID -KGEAKPDERIAFTSKDLVAHSPVTKPHADGPLTIAELCDATVTISDNSAANLLLARFGGP -AALTAFCRRLGDDVTRLDRIEPELNHDGPDDQRDTTTAAAMAETLRKLLFTDVLSAASRS -QLAAWLITNKTGDKRLRAGLPGDWLVGDKTGTNGHGNANDIAVIWPQDRAPLIVTVYCEI -PKISSKERDAVIAEIGRIAS--- ->[subseq from] Beta-lactamase n=10 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1V3D7E1_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter sp. Root690 TaxID=1736588 RepID=A0A0Q8JHM3_9GAMM ----WQTRLRDLEKHSGGRLGVAVLDTGNGQRM-AWRENERFRMCSTFKYLLAAAILRQVE -LGKVTLSQQVPITAADMIAHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP -QGLTRFLREIGDGVTRTDRTEPTLNGGAPDDPRDTSTPTAQIATMQRLLLSDALKESSRK -QLIAWLVANKTGDKRLRAGLPAGIRVGDKTGSGDD-ATNDVAIVWPPGRAPILIVSYLAT -AKLDGAGRDAVLASVARIVSEQw ->[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella zoogloeoides TaxID=352475 RepID=UPI000E65AAC0 ---KLKKRLAELEGRHKGRIGVAIHNLATGAQL-GHRADERFLMCSTFKSLLAGHILARVD -RKEEDLDRRIVVKKSDLVDWSPVVEKRVGGDISIAELCAATITLSDNAAANLLLAASGGP -KAVTQFLRGFGDEVTRLDRTEPKLNYDAPDDERDTTTPLAMTETLRRLVVSDVLSPSSKA -QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGQGNANDVAVAWSPDRGAIVVTAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=A0A1U9R0C0_STRNV ----TKGAFARLEREFDARLGVYAIDTGNSRSI-THRPDERFAYASTCKALLAAVMLDKYS ---LRQLDRLVRYDRNDLAGYSPITEKHLATGLTLRELCDATVRYSDNGAANLLFRELGGP -KSLQSALASIGDRVTRCDRYEAELSDAVPGDLRDTSTPRALATDLRAYVVDDALAPDKRA -VLTDWLKRNTTGDKVIRAGAPDGWQVGDKTGTGGYGTRNDIAVVWPPKAAPIAIAVLSRR -DFKDAEPDDALIAEAARITLN-- ->[subseq from] Beta-lactamase CARB-6 n=2 Tax=unclassified Vibrio TaxID=2614977 RepID=A0A6B8N5H7_9VIBR --dSLTKQIALIEQQSGGRLGVAVLDTQNHKQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNATTKVKKSVLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP -EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rubrolavendulae TaxID=285473 RepID=A0A1D8G8V8_9ACTN ---RVEGRLRALERTHNARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD -RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLRDLGGP -TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE -RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR -FTPDAEADNVLVAEAARLLAE-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiales TaxID=80840 RepID=A0A1E3Z895_9BORD ---AALDELARLERLADGRLGVCIVDTASGEEL-GRRADERFQMLSTFKLLAAGFVLARHD -RGEDSLDRRIRYTRQDLVNWSPVTGKHVGDRMTLAELCHATVTTSDNTAANLILRSFGGP -EALTRFIRSLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGRLTVGETLSPASRE -RLQAWLVGNTTGDKRLRAGIPAGWRIGEKTGTYSKVGANDIGLAWPPGRPAILMSVYVAS -TRVSDEVKDQVIAKVAQLVG--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus timonensis TaxID=1033734 RepID=UPI000A04C615 ---NTDEKIAQLENEFDARIGVYAIDTGTNTTI-EYRPDERFAYASTYKALAAAILLQQNT ---MEELKEVITYTKDDLVTYSPITENYVDTGMTLLEVGEAAVRFSDNTAGNILFEAIGGP -EGFEQALRQIGDTVTQADRVEPDLNFFKPGDTRDTSTPKALANSLQAFTVGESLSEDKRK -LFMEWLKDNATGDTLIRAGAPEGWIVGDKSGAGVYGTRNDLAIVWPPNREPIILAILSNH -TTEDATYDDALIARTAEVVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=UPI0002DA1818 ----ALDSIRSLEMSRGGRLGVAVLDTGSGRRL-QYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALEKPVKYGKADLLDYAPVAREHVERGMTVDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDDASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAKTf ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus (strain B4) TaxID=632772 RepID=C1AR67_RHOOB -heSLDAKIEALEAQYATRIGVTAVDPQTGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE -DGSTSLDKTVMIEPADLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDVGDASTRLDRWETELNTAFRGDPRDTTTPTGLAHGFRALLLGDALDAASRG -QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPIVLAVLTDS -LTEDAQGNSQAIADTTTAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Erwinia persicina TaxID=55211 RepID=Q8L1Z4_9GAMM ---SLQRQLAALETEVNGRIGLSLIDSASQQAW-SYRGDERFPLCSTFKLLLVAAVLKRSE -SQPALMQQTLHWTPADHLSYMPVTAKHPQ-GMTVSDLCAAALQYSDNLAANVLLTLLGGP -ASVTRLARSLGDSVTQLDRNEPTLNTAIPGDPRDTTTPLHMSHSVQQLLVKSGLQTAQQQ -QLIAWLKGNTTGKNAIAAALPAGWEIGDKTGSGGYGTTNDVAILWPPGKAPLILAIYFTQ -HAPEAKSRQDVLAKAAAIALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Thiomonas intermedia TaxID=926 RepID=UPI0009A54FFC ---ALSRAVSHAEASLHARIGIAMIDTGDGATW-SHNGDERFPMNSTYKAFACAAVLSRVD -ANTLNLDMMVPIDRARLVTYSPVTEKVQPGGLSLSDLCSAAVSVSDNTAGNLVLDAIGGP -SGFTEFMRSIGDRATHLDRLEPELNEATPKDVRDTTTPHAAATDLRKLLLGHVLSAPSKR -QLSQWMVGNKVTQGLLRAGFPSDWRVADKSGAGGHGSRSIIAIAWPPERAPIVVAIYITQ -TVAPMSRCDQTIAQLGEAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas campaniensis TaxID=213554 RepID=A0A060BEZ6_9GAMM ---NLLTEVERIERQLDARVGFAAYDLETEQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGSEQLGRRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP -QAVTAFVRDLGDSVTRLDRWETELNEAAPHDERDTTTPNAMVSNLEKLVVGNALSPQSKN -QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNTAIAELGSVIR--- ->[subseq from] class A beta-lactamase n=1 Tax=Roseomonas sp. 18066 TaxID=2681412 RepID=UPI00135AC608 ----LEKRLAEIEARSGGRLGVAIKVGGSSRQA-GHRLDEPFPLCSTFKLLAAAAVLARVD -AGQEQLDRPIRFTRDQLVAYSPGTEAGAGGPLPMRHLCEVAVTLSDNTAANLMLESLGGP -AGLTAWLRRLGDSVTRLDRIEPALNEGTPGDPRDTTTPLAMSQTMEKLLLGTALKPDSRA -LLTRWLVENKTGDERLKAHLPQGWRAGEKTGTGPRGSTNDAGILWPADGAPLLVSAYLTG -TPAPLAARNAALAEVGKAVAAFy ->[subseq from] Beta-lactamase n=1 Tax=Halomonas alkaliphila TaxID=272774 RepID=A0A386X3D1_9GAMM ---NLLTEVERIERQLDARVGFAAYDLETEQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGSEQLGRRVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP -QAVTAFVRDLGDSVTRLDRWETELNEAAPHDERDTTTPNAMVSNLEKLVVGNALSPQSKN -QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNTAIAELGSVIR--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces canus TaxID=58343 RepID=A0A101SFL6_9ACTN ---DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD -RDGEVLARRIHYTEDDLVIGSDQTAAHLAEGMTIAELAEVAITHSDNAAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDDGDPIVLAVLSTM -PAQDAVRDDALVADAARAVAD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Acidovorax TaxID=2684926 RepID=A0A1E3ZSK1_9BURK ---AWNEDLASIERTAQGRLGVAMLDTGSGLAL-GWRRDERFAMASTFKLVLAGWMLALVD -QGKERLDARVRYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGS -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTLQKLVLGNALSPTSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVLWPQGGAPVLVTCYLTR -SMASPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. Root267 TaxID=1736505 RepID=UPI00070C85DA ---QWNDTLAGIEHFAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANLLLARHGGP -AGFTAFVRSLGDGTTRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTAPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR -STAKPEQRDAAIAQVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RP5T TaxID=2490848 RepID=A0A3R8SQ78_9ACTN ---DVTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSVFKALAAAAVLRDLD -RHGEVLARRIHYTEDDLVMGSDQTKAHLAEGMTIAELADVAITYSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNSAEPWRLTDTTSPYAIGRTYGRLVLGDALNRRDRE -LFTHWLLHNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTEAGDPIVLSVLSTM -PAPDAVRDDALVADAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces fradiae ATCC 10745 = DSM 40063 TaxID=1319510 RepID=A0A1Y2NVH3_STRFR ---RVEGRLRALERTHDARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD -RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLRDLGGP -TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE -RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR -FTPDAEADNVLVAEAARLLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L849_9ACTN -----DTEFTRLEQEFDARLGVYALDTGTDQAV-EFQADERFAYCSTFKVLAFGAVLDRTP ---VEELDRVVTFSEADLVFHSPITQEHVSSGMTLHEAGDAALRHSDNTASNLLLKELGGP -EALDAALEEIGDDVTSVDRTAPEMAEAVPGDGRDTSTPRAMATSLREFALGDVLSEDERD -ILVGMMRANTTGEELIRAGVPEGWEVGDKTGACGYGTRHDIGVAWPPEGDPIVLAVMSGR -DEAGAGYDDALVAQATRVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A246HM25_STEMA -----AKDFAALEAASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGRLLLDQRVPVRQQDMLSHAPVTTRHIGKDMTVRDLCRATMITSDNPAANLLLGRVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia fluminea TaxID=134984 RepID=A0A2N3VF75_9NOCA -----TATFADLEAKYGARLGLSVVDTGTAATA-NYREGERFPMASTFKGLACGALLQAHP -LSTGYFDQVIRYTAADIVVNSPETEKHIDTGMTVTALCDAAITLSDNTAGNMLLRLLGGP -AGFTAFLRTLGDTVSRLDRWEPELNTAIPGDERDTTTAAALTANYRALVFGTALQEPERA -QLATWLKASKTGAERIKAGLPTDWIVGDKTGTPAYGSALDVAVAWPPNRAPLVLAVLTTK -PDQNADPSNDLVAEATKAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas sp. CFBP 7698 TaxID=2082399 RepID=A0A3A5EPF1_9XANT ---MLRAQWADIERGTGGRLDISLLGSAPGWRL-GQRENERFPMCSTFKFVLAAAVLRRVD -EGKLTLAQPVKIRASDMLEHAPVTKRHVGGTLSVGELCRATMIHSDNPAGNLLFPLVGDP -AGLTAFLRSIGDAKTRSDRYEPEMNGFAPGEPRDTTTPAAMASTLRTLLLGDALQPASRK -QLTDWMIDNRTGDDCLRAGLTADWKIGDKTGSNGTDTRNDIAILWPPKGPPLLLTTYLNG -AKVDAAARDAALKAVAVAVREW- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces kanamyceticus TaxID=1967 RepID=UPI0006E34FA6 ------TRLKALERKHDARLGVYALATGTGATL-AHRADERFAFCSTFKTLAAAAVLDRNP ---LSHRDTRITYTRAQVNSISPVTEDHIATGMTVKQLCDAAVRHSDGTAGNLLMRDLGGP -DRLTDYLRDLGDTVSRMDQYEPELNRARPGDPRDTTTPRAIATSYQKLVLGDALPAAKRT -LLKDWLERGVTGDKRIRAGLPKGWTVAEKTGTGFYGRANDIGIAWPGTGAPLVLAIMSDR -SGYDARPKDALIAEATAEIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI0004673903 ------RAFADLETQHTARLGVYAVDTGTGRTA-VHRDGERFPVASTFKGLACGVLLRDHP -LSTGYFDQVIRYPATDLVDASPVTQKRVDTGMTVAELCHAAITASDNTAGNQLLKLLGGP -AGFTASLRSLGDTVTRLDRWETELNTAIPGDERDTTTPAALAADYRLLVLGDVLGESERA -QLKSWLVDNTTGGARIRAGLPAGWIVGDKTGSPAYGGALDVAIAWPPDRAPLVIAVLSGK -SEPTAAADNPLVAEATRAAVR-- ->[subseq from] Beta-lactamase n=2 Tax=Acidovorax delafieldii TaxID=47920 RepID=A0A561XQU8_ACIDE ---AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLEARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSSMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSGTANDIGVLWPAGGAPVLVTCYLTR -SKASPEQRDAAIAQVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces bungoensis TaxID=285568 RepID=A0A117R9V7_9ACTN ---EIVRRLKGLEQRHAARLGVHARDTATGRTV-RYRADERFPICSVFKTPAVAAVLRDLD -RDGEFLARRVRYTERDVRDYAPITGRNLAAGMAVEDLCAAAIRHSDNAAANLLLRELGGP -AAITRFCRSIGDRTTRLDRWEPDLNSAEPWRATDTTSPCAIGRTYARLVLGTALAPGDRE -RLTGWLLGNTTGGERLRAGLPGDWTVADKTGTGSYGTGHDVGVTWPPGRAPLVLAVLTTR -HEPDASPDSRLIAETAALL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis tolypomycina TaxID=208445 RepID=A0A1H4UTV2_9PSEU -------DFAPLERSFDARLGVYALDTGSGREI-AHRADERFGYASAHKALSAAAVLQRTS ---LDGLAKHLTYTRADLRANSPVTEKRVATGISLRDAIDAALRYSDNTAANLLFRELGGP -PGLAAALRGIGDTTTHVDRIEPELNDLAPGDVRDTSTPRAMAGTLRTFALGDALPPEKRT -VYTDMMRANQTGATVIRAGTPAGWAVADKTGTGEYAMRNDIAVVWPPGRAPIVLAVMSSR -QAEDAEHDDRLIAQAAKLVFDAf ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus eapokensis TaxID=1873482 RepID=A0A1Q5TSU0_9GAMM ----IIHQLSILEKNANGRLGVVLLDTTDHSII-SYRENERFPLCSTSKLMTVSAMLKKSE -TNVHLLNQRVHYQQSELVEYSPMTEKHLKDGMTLGELSAATLQYSDNTAMNLLLNQLHGP -NEVTRFARIIGDNSFRLDRYEPELNTAIPGDERDTSTPQAMAKSLYYLVLGDALATTQRE -QLVKWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPPNRAPLVLVTYFTQ -PDSKATARPDVLAAAARIVTQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0005173611 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGSAGYGTRNDIAVIWPPDHAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HJA8_9BACT -------SIAEIEARVGGRVGVFALDTGSGKVL-AHRPDERFAMCSTFKWVLAATVLAQVE -RNLLSLGDHVLYGQADLLAYAPVTSKHAAKGMTVSDLTRAAIVVSDNTAANLLLSKLGGP -SVVTEFARSCGDAITRLDRNEPTLNDNESGDLRDTTSPRAMATLMNKVLCGNRLSSTSRD -LLLQWLRDCDTGHDRLRAKLPKDWLVGDKTGTGEHGAVNDVAIAIPPGRSPILIAAFLSE -GKADRSALVAAHASISRLVADHf ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0005B620D1 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGSAGYGTRNDIAVIWPPDHAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C9FBC92 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVI---- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000BACEBBF -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces caatingaensis TaxID=1678637 RepID=A0A0K9XIQ2_9ACTN ------APFRQLEQRFGARVGLYALDTGTGREV-TYRADERFAHCSTFKALAAGALLHHAS ---DAELDQVVTYRPEDLQKWAPIARKHVATGMKLREVAAAAAEYSDNTAANLLLDHLGGP -AGLQKELRGIGDSTISTDRTEPGLSDAVPGDTRDTSTPRSIATDLRRYVLGSVLSDGRRQ -LLTDWLVHNTTGDRYIRAGVPAGWKVGDRTGNGGYGTRNDIAVAWPPGRSPVVIAVLSDR -GEAGARSDDALIAEVTKAAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces pratensis (strain ATCC 33331 / IAF-45CD) TaxID=591167 RepID=E8W3G7_STRFA -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ASRGAKPQDALIARAARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RKND-216 TaxID=2562581 RepID=A0A4S2R6B1_9ACTN ---RLVRRLTELENRHAARLGVFAHDTATGRSV-RYRAQERFPMCSVFKTLAVAAVLRDLD -RHGEFLARHVRYDEKTVTDYAPVTGKNLAHGMTVQELCDAAIRYSDNAAANLLLRALGGP -RAVTRFCRSVGDRVTRLDRWEPELNSAEPWRRTDTTTPRAVAGTYARLTLGDALDRADRR -RLTGWLLGNTTSGAKFRAGLPDGWVVADKTGGGEYGTNNDVGLTWPPGRPPIVLAVLTTR -FTPDAERIDPLVAETASLVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis baichengensis TaxID=280240 RepID=UPI00034671FB ------AGFERLEEEFGARLGVYALDTGSGEEV-AYNADERFAYASTFKVPACGAVMEEHS --LKEMEETVVHFDEEDLVTYSPITEDHVDTGMTLMEVCDAALRYSDNTAANLLLEEIGGP -EGFQEAMRELGDEVTVSARWETELNENKPGDERDTSSPRAFAGNLEEYVLGDTLEEDKSE -ALADMMVRSTTGDTLIRAGVPEDWKVGDKSGMPGYGARNDIAVMWPPEGDPIVLAAYSTK -DTEDAESEDELIAQAAEEAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI00111F8AAC --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -QGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLAAQKLGGP -QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA -QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PsTaAH-124 TaxID=1157638 RepID=UPI0003619AD3 ---RATDALRALEERYSARLGVHARNTRTGQSV-GYRAGERFALCSTFKVFAAGAVLRDHA --GSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP -AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPQALGASLERLTVGDELSGAARE -QLLTWLKGNTTSAARFRAGLPRGWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSK -DAPDATVDEALIADAAAVLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. T7 TaxID=627444 RepID=UPI00135C1BC6 --qSLDAKIEALEAQYATRIGVTAVDPATGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTRSDNTAGNYLLREIGGP -QAITALARDLGDESTRLDRWETELNTAFRGDPRDTTTPTGLAQGFRALLLDDALDAASRD -QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPVVLAVLTDS -LTEGAQGNNQAIADTTAAVIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A5P2X6C3_STRST ---AYARAFRKLEHKFDARLGVYAVDTGTGREV-AYNDSRRFAYNSTFKALAAAEVLRQYA ---PDRLDQVVKYSKDDLIANSPVTEKHVDTGMTLRALCDAAVRYSDNTAANLMFDKLGGP -KGLDAALERIGDDVTRMDRVEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDVLAAPERA -QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPGAAPLVVAILSHR -GDRDAAPDDKLIAEAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillaceae bacterium TKL69 TaxID=2594883 RepID=A0A516KC56_9BACI ------KDFAKLEKTYDARLGVFALHTGTNEMI-AYRADERFAYASTHKALAVGALLQQKS ---IPELNKRIRYSKNDLVNYNPITEKFVELGMTLKELCEASIRYSDNTAGNLILNELGGP -NVFKQLLEAIGDTITNPVRMEPELNDVEPGEIQDTSTPRALATSLQAYTLGDVLENEKRA -LLVDWLKRNTTGDNLIRAGTPKGWVVGDKTGAAAYGTRNDIGIIWPPNDAPIILSVLSSR -NQEDADYDDQLIADATKSVIKTf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. DOA1 TaxID=1126616 RepID=A0A150ZHX4_9BRAD -------EFEAYERESGGRIGVHAENLASGAKL-AWRADERFVMCSTFKASLAACMLARVD -RGEEQLAAMIPYREADLLEYAPVARQNLAAGMSVSEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTSTPAAMAGNLRRLVLAEALSPASRA -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDIAVVWPKPDTPILITAYVQG -GAPSAAQIAAVFARIGRMVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=Q8EMP8_OCEIH -----SEDLKKLEEEFDVRLGVYAIDTGADKEI-SYRENERFAYTSTFKPLAVGAVLQTKS ---DEELEETITYSEEDLVTYSPITEQHVDEGMTLVEIADAAIRYSDNTAGNLLLEAMGGP -DELETILRDIGDETIEMDRYETELNEAKPGDIRDTSTAKAMATTLQQYVLEDVLDADRRE -VLTNMLINNTTGDALIRAGVPDGWTVGDKTGAGGYGTRNDIGIIWPEDEEPIVIAIMSSR -DEEDADYDDKLIEKATEIVLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sacchari TaxID=1399419 RepID=A0A560KDX9_9BRAD -------ELESYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAASVLARVD -RGEEQLAAMIAYGEADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTSEALSPASRR -RLTDWMVNCKTGANRLRGGLPADWKIGDKTGYNGKDAAGDIAVAWPKPDAPVLIAAYTQG -GTPTAPQIEAVFARIGRMVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavovirens TaxID=52258 RepID=UPI0004C587B2 -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ASPGAKPQDALIARAARVAL--- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CC901F ---DAERRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -DAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAMTRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000477D042 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDTSYDNALIAQATEVVIA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. H219 TaxID=2492662 RepID=A0A426JWF2_9PSEU -------ELVELERRYDARLGLFARNTATGRTL-SHRADERVALCSTFKVYASAALLRAHG -LAGGYFERVIRYDAGQLVEYSPITEGRVGTGMTVGELCAAALQHSDNTAANLLLRELGGP -QAITEFARSIGDPATRLDRWEVELNTAIPGDERDTSSPRALADGLQRLLLGDALGAAERD -RLTAWMLGNTTGDARIRAGVPRGWRTADKTGGGSYGVANDIAVTWTETGTPIVLSLLTSR -PREDDTANNALLADATRLVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis halotolerans TaxID=124252 RepID=UPI000346189A ---EFAAEFERLEEEFDARLGVYAVDTGTGEEV-AHRSDERFAYASTHKAFTAALVLDQNT ---PEEMEEVVTFTEDDLLEYAPITEQHVDTGMTLMEVTDAAVRYSDNTAANLLFEELGGP -EAFDDAMEAMGDDVIEANRVEPGLNDWAPGDDRDTSTPHAMAESLREFTLGDVLPEEKRS -VLTDMLVNNTTGDELVRAGVPEGWEVGDKTGAAGYGTRNDIAVLWPPEGEPIVLAVMSSR -DEENAEYDNALVAEAAEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI0003914B0E --dSLTKQIALIEQQSGGRLGVAVLDTQNHKQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVQKACEATMLMSDNTAANIVLHQIGGP -EQVSQFVRSLDDKVTRLDRFEPELNQAIPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALMWNSQRKPVILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2W6J0T0_STEMA -----TSDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus manasiensis TaxID=586413 RepID=UPI0005AA8553 -----EEIFKELEAEFDARLGVYAIDTESDQTV-TYRSNERFAYASTFKVLAAGAILQTKP ---KEELEKVITYSEDDLITYSPVTENHVDDGMELKEIMEAAIRYSDNTAGNLLLEELGGP -EGLEEILREIGDETIEVDRIEPDLNEAAPGDTQDTSTPQALAESLQKYVLSDLLPKDKRD -LLTDWITGNEAGDTLIRAGVPEDWKVGDKSGAGGYGTRNDVAVIWPPNQEPIVIAILSSR -DTTDADFDDTLIEKATEHVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. Root102 TaxID=1736422 RepID=A0A0Q6NHU2_9RHIZ -------KIRRIEAKSGGRLGVACQIAGTSAQF-GYRENELFPMCSTFKTLAAALILHRVD -GGIEQLERSIKIPHNAVIANSPTTRKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP -PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTTSPLAMVEDYGRLALGNSLSDKSRA -QLVDWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG -TKQGLAKRNAVIASVSRVLVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia sp. LLH-Slr-6 TaxID=1564800 RepID=A0A097SRR9_9BURK -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDQRDTTMPAAMATTLRKLLTAELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAVGPNGKPSRIVVISNT- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia transvalensis TaxID=37333 RepID=UPI0006874B6C ----TSKPFAELENQHTARLGVYGIDTGSGRTV-AYREGERFPIASTFKGIACGGLLRAHP -LSTGYFDQVIHYPATDLVANSPITEKRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP -EGFTAFARSLGDTVTRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLAKPEQD -QLKSWLVANTTGTARIRAALPQDWTVGDKTGSPDYGGALDIAITWPPNRAPLVIAVLTAT -TNPNAQPNNPLVAAAAHN----- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. Root568 TaxID=1736565 RepID=UPI0006F21CE0 ---AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLEARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGNALSSMSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSGTANDIGVLWPAGGAPVLVTCYLTR -SKASPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Silvibacterium bohemicum TaxID=1577686 RepID=UPI0006793777 ---TLPTALARLEQTSGGRLGVSVLDTANGTRT-GHRADERFPMCSTFKFLLASAVLQRVD -SHRETLDRAISIPPKPLVPYSPLTEPHAGGTMTISDLCHAALTRSDNTAANLLLESIGGP -SGITAFSRSIGDQVTRLDRTETSLNESLAGDPRDTTSPRAMADDLKSVLLGNVLSSVSRD -QLTQWMEANLTGLERLRANLPQGWRAADKTGSNGEHTTNDIGVFWPVGRPPVIVTAYITQ -CPGQESKRGAMLAEVGRLV---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. CNZ304 TaxID=2512143 RepID=A0A4Q8C0C2_9ACTN ------REFERLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEEDLVDYSPITEQHVDTGMTLMEVADAAVRYSDNTAANLLFEELGGP -DAFEDELEAIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGNLREFALGDALPEDRRE -VLNDLLVNNTTGDALIRAGVPEDWRVGDKTGAASHGTRNDIAVIWPPEGDPIVLAVMSSR -EAEDAEYDDALVARAAEVVAE-- ->[subseq from] Beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=Q92Y20_RHIME --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAINLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHANNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. WN018 TaxID=2032624 RepID=UPI000BAB2ED8 ---NLLTEVDRIERQLDARVGFAAYDLETEQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGSEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATMATSDNTAANLILQAIGGP -QAVTEFVRELGDSVTRLDRWETELNEAVPSDERDTTTPNAMVSNLEKLVVGNALSPQSKN -QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPERKPIIVAFYITE -TTASFEDRNTAIAELGDVI---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KE1 TaxID=1638939 RepID=A0A0H1ADI5_9ACTN -------ALRTLERKYDARLGVYALDTGTGKTI-GHRAGERFAFCSTFKTLAVAAILDRNP ---LGHLDKHVTYTRDDINSISPVTRKNVDKGMTVGQLCDAAIRYSDGTAANLLLRDLGGP -ERLTDYFRELGDTVSRLDHYEPELHRVRPGDPADTTTPRAIAADYRTVVLGDTLARDRRA -LLTDLLERNKTGGNRIRAGVPKGWRVADKTGTGQYGRANDIAIVWPPASGPLVLAIMSER -SGREARPSEALIAEATEHVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinobacteria TaxID=1760 RepID=UPI0002EB480C -------AFAALESTYDARLGLSVLDTGTDRVV-AYREHERFPMASTFKGLACGALLQAHP -LATGYFEQVIRYTAADIVVNSPETEQHIDTGMTVTALCDAAITQSDNTAGNLLLRLLGGP -EGFTAFLRTLGDQVSRLDRWEPELNTAVPGDERDTTTAAALAADYRALVVGTALAEPERA -QLAAWLKASRTGAKRIKAGLPADWTIGDKTGTPAYGSALDVAVAWPPGRAPLVLAVLTTR -TEKDADPVNELVAEAAKTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI000DA7FD4B ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DTDLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRAEPDLNQAIPGDRRDTTTPERFAANLRTVLLGDALDAADRR -VLLEAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] Beta-lactamase 1 n=1 Tax=Streptomyces sp. F-1 TaxID=463642 RepID=A0A1K2FJX0_9ACTN -------ELGDLERDYGARLGVYARNVRTGRVL-AHRAGERFAHCSVFKAFAAAAVLRDRS --GCAPLDKVIHYPPHDILPNSPRTEENQETGMTVADLCAAAIQYSDNTAGNLLLQQVGGP -AGLTGFFRSLGDRVSRQDRWEPELNTAIPGDLRDTTTPEAIATSLERLTLGRALPAPDRE -RLVTWMKGNTTSGARFRAGLPEGWTLADKTGTGFYASAHDIGVAWTTRRTPVVLAVLSTK -DEKDAPVDEALIREAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Luteimonas sp. 100111 TaxID=2006110 RepID=A0A290XCD2_9GAMM ---TLDAALAALEQAAGGRLGIAVLDTGTGRRL-GRREEERFPMCSTFKALLAGAVLHAVE -RGHVRLDQPVDVAAGDLVPYSPYVETRLAQGARVDDLCRATVTLSDNAAANLLLPLVGGP -SGLTAFLRALGDPVTRLDRWEPDLNEAARDDPRDTTSPRAMVDSLQRLLFGDVLRAPLQA -VLAAWLIENRTGEARIRAGVPAGWIVGDKTGTCGAGTAADVAVLYPPGRAPLLLAVYVHG -AGVSGPAIDALHADVARAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chilikensis TaxID=1194079 RepID=UPI001408A6A1 -----VARLRELERRHGARVGVHAWNTVTGTTV-RHRADERFPILSVFKTLAAAAVLRDRD -RDGEFLDRRIRYTEAQLVENSDVCEANLATGMTVRELCAAAVQWSDNTAGNLLLRQIGGP -HGITRFARSLGDPVTRLDRWETELNSGEPWRETDTTSPGAIAATYARLVLGGALERPDRE -LLTSWLLGNRTGRTRLRAGLPPEWTIADKTGAASYGSLNDVGVVWTEDGTPLVMAVLTTK -PERDAPRQDVLLEDVARILAD-- ->[subseq from] Beta-lactamase n=1 Tax=Terribacillus saccharophilus TaxID=361277 RepID=A0A268HGY2_9BACI ------ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---IEDLNKRVMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -DGFEDGLRKIGDQVTNSERIEPDLNNTQPGNTRDTSTPKAMAESLREYALRDHLSADKRQ -LLVDWLKGNTTGDALIRAGVPKDWEVGDKTGAGSYGTRNDIAILWPPDEEPIVLAIMSDH -DEADANANDDLIAEAAEAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces glaucescens TaxID=1907 RepID=UPI000A385B89 ------GRLRALEREYGAKLGVYAHNVGTGRTI-RHHADDLFPICSVFKTLAAAAVLRDLD -RDGEFLARRIHYTEADLVDGSDETRKHLAEGMTVAELCDVTIRYSDNAAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE -LLKHWLLNNTTSLDRLRAGVPPTWTVADKTGGGDYGVNNNVGIAWTPDGTPVVLAVLSRK -SDPAAVRENALIAKTAKVLTE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia asteroides NBRC 15531 TaxID=1110697 RepID=U5E5U8_NOCAS -------AFAALESTYDARLGLSVLDTGTDRVV-AYREHERFPMASTFKGLACGALLQAHP -LATGYFEQVIRYTAADIVVNSPETEQHIDTGMTVTALCDAAITQSDNTAGNLLLRLLGGP -EGFTAFLRTLGDQVSRLDRWEPELNTAVPGDERDTTTAAALAADYRALVVGTALAEPERA -QLAAWLKASRTGAKRIKAGLPADWTIGDKTGTPAYGSALDVAVAWPPGRAPLVLAVLTTR -TEKDADPVNELVAEAAKTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes philippinensis TaxID=35752 RepID=A0A1I2N0T1_9ACTN -----APSFSGLEQRFGARLGVYALDTATGRTV-AHRANERFAHASTVKALQAGVVLRGAS ---DDDLRTVVRYERSDLLGHAPITTEHVDTGMSLGDLLAASLRYSDNTAANLLFEHLGGP -DALERELRSLGDRTTSVDRIEPQLNEARPGDTRDTSSPRALGATLQTLVLGDALPVARRD -QLTTWLRGNTTGGPYIRAGVPAGWVVADKTGSGGYGTRNDIAVVWPPAGAPLVIAVMSDR -GVRDAPSADSLIAEATAKVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0005349BCD ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDRRDTSTARALTEDLQEYAVDDALDPTDRD -ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEPDASFDNALIAEAAGVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. CAH-2 TaxID=2605745 RepID=UPI0012ADDAD1 ---HWSQAMAQIEQDAQGRLGVAMLDTGSGLAL-GWRQDERFAMCSTFKLPLAAWVLALVD -QGRERLDARVQYSEADLVEYSPVSGPKAGAGLTVGELCSATVSLSDNSAANVLLARHGGP -AALTAWLRSQQDSITRLDRNEPSLNEAAVGDERDTTTPLAMLHTMQRLVLGTALSPSSRA -TLQRWLIETSTGDQRLRAGAP-GWKVGDKTGTSGSGTANDIGVLWPPGGAPVLVTCYLTQ -STARPEQRDAAIAQVARAVLT-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia takedensis TaxID=259390 RepID=UPI000A02BF59 ---DAAAAFADLETSAGARLGVHAVDTADGQVL-AYREHERFPMASTFKGLACGALLREHP -LSSGYFDQVIRYGADEIVDASPATSRHLDSGMTVAELCEAAITLSDNTAGNQLLKLLGGP -AGFTAFLRSLGDQVSRLDRWETELNTAVPGDERDTTTAAALTADYRALVVGDVLGAPERE -RLTSWLVANTTGDKRIRAGLPAEWRVGDKTGSPAYGSALDVAVTWPPGRAPLVLTVLTTK -PDRDATADNALVAAAARLAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodobiaceae bacterium TaxID=2026785 RepID=A0A2A5EVG5_9RHIZ ---NLIETIKAVEKRIGGRVGAAIYDTETGRNW-EYRARERFPLSSTFKAFACAAVLSRVD -QGAEQLDRVIEIQESDLVTYSPVTEKRIGTEMTLSDLCNAAVTLSDNTAGNIILQSLGGP -EGFTNYMRTIGDPMTHLDRWETTLNEGAPNDMRDTTTPQAAANSLHTVLLGDVLSASSRQ -QIXDWMRXDXVAGALXRSAVPTXWQXADKTGAGGHGSRSIIAVMWPPQRKPIIATVYMTX -NSAEFADRNAAIAEIGAAIVS-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_021 TaxID=2175665 RepID=A0A2W1RNS5_9MICO ----ATRAFSALEAEHAARIGVVAVDTADGATV-AHRAGERFPFASTAKVFIAAAVLDDAA ---GSDLAAVVPIGPRDLLSYAPVTSRHVGTGMTVRALLDAMIRTSDNTAANLLVSRIGGP -AAVQSWLRGIGDDVTRVDRVEPDLNAAVPGDERDTTTPSQFAADLRTVLLGDRLDPDDRA -LLVDLMRGTTTGAGTIRAGVPAGWSVADKTGTGSYGVRNDVGIVTPPGRAPVVLVVMTSH -DTADAQPDDALVAAATRTAID-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A CARB-5 n=1 Tax=Labrenzia marina TaxID=281252 RepID=A0A2S3UX95_9RHOB ----LARAVEDISSRLPARVGVAVIDMETGTRW-AHKGDERFPTNSTFKVFLCAALLDAGV -RGTADPDSRVTIRRGDIVSYSPVTEKRIDGAVTLRELCGITVTISDNAAANLVMKEIGGP -QALTAYLRGIGDSVTRADRWEPDSNSGIPGDDRDTTSPNAAAETLKKLVLEEALPADARQ -TLTNWLTGNKVGDATLRAGLPDNWRIADKTGAGANGSRNNIAVIWPDGRAPVVIAVYITE -TSASFEARNGAIAEIGAALAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013102FFA ----TATDFAALEKACAGRLGVSLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVLGEVLRPASRQ -QLADWLIDNETGDECLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRAMVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium centrolobii TaxID=1505087 RepID=A0A176YAR2_9BRAD -------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAKIPYGQADLLEYAPVAKQNLAAGMSVVDMCRAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPVAMAGNLRRLVLGESLSPASRG -QLTDWMLNCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPSPDRPILIAAYTQG -GTPTAAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis mediterranei (strain S699) TaxID=713604 RepID=G0FMS0_AMYMS ------PDFAPLERSFDARLGVYALDTGSGREI-THRADERFGYASTHKVFSAGAVLRRTS ---LDGLAKNLTYTRADLQPNSPVTEKHVTTGLSLREAMDAALRYSDNTAANLLFRELGGP -AGLAAALREIGDTTTHADRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQT -VLTDMMRANTTGAALIRAGAPAGWAVADKTGSGSYATRNDIAVVWPPGRAPIVLIVMSSR -QAESADHDDRLIAQAAKLALDAf ->[subseq from] Beta-lactamase n=2 Tax=Xanthomonas TaxID=338 RepID=A0A5D1A8F8_9XANT ---TLPRRLAEIERRSGGRLGVSLLD-GGGATLgGQRQNERFPLCSTFKFLLAGAVLQRVD -RGELALERRVPVRKADLLANAPVSERHVGGTLSVVELCRASMIYSDNTAANLLLPLVGDP -PGVTRFLRALGDTQTQLDRNEPGMNEFVAGDPCDTTTPAAMAATMRALLLGEVLQPVSRQ -RLIAWMRDNRTGNDCLRAGLPAGWRIGDKTGSNGTDTRNDIAIVWAPGRTPLLLTAYLNG -ATVDSAARDATLKAVAQAVVA-- ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653WC68_9GAMM ---SLDDALAALEHAAGGRLGIALLDTGTGRRF-GRRDDARFPMCSTFKALLAGAVLHAVD -RGRVRLDQRVDIGAGDLVTYSPYVETRVADGARVDDLCRATVTLSDNAAANLLLPLVGGP -PGLTALLRELGDPVTRLDRREPELNEAAAGDPRDTTSPRAMIDSLQRLLFGDALRPPSQA -VLAAWLIENRTGDARIRAGVPGDWRVGDKTGTCGAGTAADVAVLYPPGRAPLLLAIYVHG -AQLDGPAINALHADVTRLLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ329 TaxID=1298879 RepID=UPI0004883A28 ------RQLAELEREYDARLGVYAVDTGSGREV-AHHADERFPYASTFKALAAGVVLRTRP ---AAELDRVLTYSADDLIAHSPVTAEHVATGMTLRDLCEAAVRSSDNAAANLILAELGGP -AGMDAELEAIGDDVTRMVRNEPELSRWTPGDTRDTTTPRALARGLRTFVLGDALDKPARG -LLTTWLRTHTTGDTLIRAGVPSAWTVGDKTGTGSYGARNDIAVLWPPDRAPLVVAIMSHR -TERDAEADDELLAEAASEVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8QDC9_9ACTN ----TKAAFARLERRFDARLGVYAIDTGNGRSI-THRPDERFAYASTCKALLAAVMLDRYS ---LRQLDRLVRYDRNDLAGYSPITEKHIATGLTLRELCDATVRYSDNGAANLLFRELGGP -KSLQSALASIGDRVTRCDRYEDALSAAVPGDLRDTSTPRALATDLRAYVVDDALAPDKRA -VLTDWLKRNTTGDKVIRAGAPDGWQVGDKTGTGGYGTRNDIAVVWPPKAAPIAIAVLSRR -DFKDAEPDDALIAEAAGITL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=UPI0013DBFA35 -----EARLAALESKHPGRICVSILDMANGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -QALTAFCRSLGDEITRLDRTEPTLNYDRQDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PTIAADERNAIVAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI00083177FA ----FTGAFRKLEHAYDARLGVYAIDTGTGREV-AYRDGERFAYASTFKALAAGAVLRKYS ---LSGLDRVIRYAKDDLVDYSPVTEKHVKTGMTLGALCDAAVRYSDNTAANLLFDVLGGP -KGLDAMLEKMGDDVIQMENEEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDALGKPERT -QLTKWLRTNTTGDELIRAGVPKGSVVGDKTGNGSYGARNDIAVVWPPDSAPIVLAIMSWR -GDKDTTFDNKLIADAASVVAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI00112F1E65 ---STARDFATLEAASGGRLGVTLLDTGSGQRI-GHRQDERFPMCSTFKFALCATVLRLAD -QGKLSLDRRLAMTTQDLLSHAPVTARHVGKDVTVRDLCRATMVTSDNPAANLLLRVVGGP -AGVTAFLRASGDDVTRNDRYEPEVNRFAPGDPRDTTSPAAMAASLQRLVLGERLQPASRQ -QLADWLIDNETGDAHLRAGLSNAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ARLDGAGRNDILRQVAVIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia vermiculata TaxID=257274 RepID=UPI0008326F9E ------DEFQGLEARLHGRLGVYALDTGTGRAV-EYRADERFPYASTFKALAAGAVLSKLT ---PADLYRHVTYSRADLLPNSPITEKHVDEGMTISEILDAAVRYSDNTAGNLLFAELGGP -KGLQQQLRDIGDTTTQSDRTETSLNEAIPGDERDTSSPQAMAEDLRHYVLDPAVDAEDRE -ALTGLLRTNTTGAALIRAGVPADWVVGDKTGGGEYGTRNDISVVWPPGRAPIVLTVLSTR -DRPDAEFDDSVIARAATIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7N1W4_9BACT --------FGSIERQVAGRLGVAALDTATGRRL-AYRADERFAMCSTFKWLLGAQILSRAD -AGAEQLSRVVPYGETDLLEYAPVTRAHVREGMTISELVSAAIRFSDNTAANLLLHTIGGP -ASFTAYLRQLGDRITRLDRVEPDLNSAIPGDVRDTTTPKAMVANLGVVLLGDHLGRAARD -QLIAWLVGSTTGTDKLRAGLPATWRVGDKTGMGGHGATNDVAVAWPVNRGPVLVAAYLAD -TEADVAGRNDALADVGHAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces somaliensis TaxID=78355 RepID=UPI00049547AF ---RVEGRLRALERAHGARLGAFAYDTGTGRTV-AHRADELFPMASLFKAVAVAAVLRDLD -RDGEVLARRLHYTERYVREFSPVTERNLANGMTVAELCDATLTRSDNTAGNLLLRELGGP -TAVTRFCRSVGDGVTRLDRWEPELNSAEPWRTTDTTSPRAIGRTYGRLLLGDVLAAPDRE -RLTRWMLANKTSDERFRAGLPADWPLADKTGGGGYGSNNDAGVAWPPGRPPVVLAVLTTR -FAPDAAADNALVAEAAALLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas oryzae TaxID=347 RepID=UPI0002D47941 ---MLRAQWAEIERGTGGRLGIDLLDSATGWRL-GQREDERFPMCRTFKFVLAAAVLQRVD -QGKLTLAQRVKIRASDMLEHAPVTERHVGGSLSVGELCRATMIYSDNPAANVLFPLVGDP -AGLTGFLRGIGDAQTRSDRYEPETNRFAAGDPRDTTTPAAMVATLRTLLLGDALQPSSRQ -QLTDWMIDNRTGDDCLRAGLTRDWKIGDKTGSNGSDTRNDIAILWPPKGAPLLLTTYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Microbispora sp. GMKU363 TaxID=718014 RepID=UPI0006E38E5C ---EARRKLRALEAAFKGRIGAYAVDTASGKTV-AYRSGERFPLLSTFKAVAAAAVLHKAR -TDPGLMDRVVRWSRDDLKPHSPITEKHVGDGMTVARLCEAAIRYSDNTASNMLLKQIGGP -AGLTRYFRTLQDPISRLDRWESELNDWNPKERRDTTTPESMARSLHAVTIGDALDAKDRD -RLNGWLTANTTGDARIRAGLPKDWTIGDKTGTGGYGTANDIAVVWPAEAAPIVMAIYTNR -RAADAPGDDKIVAETAAILV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. LLH-Irr-21 TaxID=1564876 RepID=A0A097SRT0_9ACTN ------VRVKDAEDQWGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNKGDHVTRLDRWGPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQA-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. SGNA-20 TaxID=2493088 RepID=UPI000F639CDA -----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD -RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP -AALTAFLRGLGDTVTRSDRLEPEMNGFAPGDTRDTTSPRAMATSLGRCVAGAVLAPASRL -QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG -SRVDSAARDAVLARAGQLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Kushneria phyllosphaerae TaxID=2100822 RepID=A0A2R8CPZ3_9GAMM ---EVKRKLEALEQRHGGRVGVALMNVATGETV-SHRGDERFLFNSTGKVFIAAAVLAQVD -RDRISLDQRIEVKTSDLTGWTPITEKHLGGPMTIAELCQAAVAWSDNAAANLLIERLGGP -ADITAFLRSIGDITTRLDRTEPTLNEDHDGDERDTTTPLAMMQTLRTLLLGEALSPSSRH -QLAAWMIEGKMGDARLRAGMPADWLVGEKTGTNSVGNAADIGIAWPSDRGAVIAIAYVYL -PQADKAQRDQVIKDIGTLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID1046 TaxID=2690249 RepID=UPI00136871B4 ------AGLRALEREYGARLGVYALDTASGRTV-AHRADELFPMCSVFKTLAAAAVLRDLD -HDGSHLAKRIHYTLQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNAAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTGPRAIGRTYARLALGDALDPGDRE -LLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRQPIVLAILSTM -PEATAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF90_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3D0GCZ0_9GAMM ------ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSAAVLHLAD -QGRLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGEVLTPASRL -QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDTLRQVAVIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110028 TaxID=1621260 RepID=UPI0006E157CD ------GELKALEREFDARLGLYAIDTGTGREV-AYRAGERFGFHSTHKALTAGAVLRRYS ---LGGMDKVITYSRDDLIDNSPITEKHVDTGMTLRELCDAAVRYSDNTAANLLFDVIGGP -KALQREVRRLGDDITRMDRVEPDLSRWTPGETRDTTTPRALAGDLRAFVLGDVLRKPERA -KLATWLRTNTTGDALIRAGVPEGWVVGDKTGSGGYGARNDIAVVWRPGAAPIVMAVMTNR -GEEDDAHDDKLIAKAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS090A TaxID=2162710 RepID=A0A2T7KKY9_9ACTN ----TDRAFAELERKFDARLGVYAIDTGDGRTV-THRPDERFAYASTCKALLSGAVLAKKT ---LPQMERLVRYGQEEIISHSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYTLGSALPAEKRA -LLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPSGGAPIALAVLSRR -DIKNAETDDALIAGAAKVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. cf386 TaxID=1761904 RepID=A0A1H0SH49_9ACTN -------SLRALERKHDARLGVYALHTGTGTTV-AHRADERFAFCSTFKTAAVAAVLDRNP ---LSHLDKRVTYGWNDINSISPVTRKNVTQGMTIRQLCDAAVRHSDGTAANLLLRDLGGP -QRLTAYLRELGDTVSRLDHYEPELHRARPGDPNDTTTPRAIAADYRTIILGEALATDKRA -LLTDLLVRNTTGGNRIRAGLPKGWRVADKTGTGTYGRANDIAVVWPSGSEPLVLAIMSER -AEREARPSESLIAEATEQIA--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas prunicola TaxID=2053930 RepID=A0A2N3RNH9_9XANT ---ALRARWVEIERRSGGRLGISLLDTATGQRI-EQRQDERFPLCSTFKFLLVAAVLQRVD -RGELRLDRQVPIRAEDMLSYAPATKPHVGGSLSLAELCQAAMIFSDGVAANLLLTQVGDP -VGLTAFIRTLGDTQTRSDRNEPSMNNFALDDPRDTTTPAAMLGSMRAVLLGDALQPASRK -RLTDWMIDNRTGDDCLRAGFPQGWKVGDKTGNNGTDSRNDIGIVWVPGQAPLLLTTYLNK -ATVDADARDAALKAVAQAVAAWw ->[subseq from] Beta-lactamase n=1 Tax=Glycomyces fuscus TaxID=1407559 RepID=A0A2A6F543_9ACTN -------EFERLEEEFDARLGVYALDTGTGRVV-EFQADERFAYCSTFKALAFGAVLDRTP ---VDELDRVVTFSEADLVFHSPVAREHVATGMTLREIGDAALRHSDNTASNLLVEELGGP -KALEEALRGIGDDVTRVDRLAPEMAEAVPGDDRDTSTPRAMATSLRAFALGDVLPEDGRE -VLVDMMRANTTGDDLIRAGVPEGWTVGDKTGACGYGTRHDVGVLWPPEGAPVVLAVMSSR -DEAGAGYDDALVARATETVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. M41(2017) TaxID=1955065 RepID=A0A1V9K156_9ACTN -----APSFARLEREFDARLGVHALDTGTGKAV-AYRPDERFAFASTYKALAAGAVLRRNT ---PAGLERVVPYTRAELVAHSPVTERHVESGMSLRALCDAAIRYSDNTAGNLLFDELGGP -KGLQAELAGLGDTTTRADRYEPALNEATPGDPRDTSTPRALTSALYAYTLGGVLDSEKRA -LLLDWLGRNTTGGALIRSGVPAHWKVGDKTGNASYGTRNDIAVVSPPGAAPILLAVLSSR -AARDAASDDRLIARATEVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces triticirhizae TaxID=2483353 RepID=A0A3M2M2Q1_9ACTN ---SAEEEFGALEGEFDALLGVHAVDTGTGREV-AHRADERFAYASTFKALLVGAVLDEHG ---ANGLDEVITYTADDLLDNSPVTENFVGSGMSLRELCAATLWYSDNAAANLLLDVAGGP -EALEAWLRQLGDDTTRMDRWEPDLSEGIPGDDRDTSTPRALAADLRALLLGDALGDAERA -LLRAWMETNTTGETLVRAGVPAEWTVADKSGTAGYGGRNNIAVVWPDDGEPIVLAVMSRR -DQPGAERDDALIARAATVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00047F8F47 -------GFRRLEKRFDARLGIYAIDTDTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DELDASYDNALIAQATEVVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces californicus TaxID=67351 RepID=UPI0004BE5A2F -----TAAFEKLERAFDARLGVYAIDTGTGREV-VHNDRARFAYNSTFKALQAGVVLGKYS ---LDGLDRRVTYTRKDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGMDASLEKLGDDVTRMDRVEPELSRWVPGEKRDTSTPRALAGDLRAFVLDGALPAPERE -QLTTWLRTNTTGDAVIRAGVPKNWVVGDKTGTGSYGARNDIAVVWPPDSSPIVIAILSNR -ATKDAEPSDELIAEAASVVAD-- ->[subseq from] Beta-lactamase n=10 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9F279_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000377FE18 ---DLHHEFRRLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTFKALAAAEVLDATT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAVADAAVRYSDNTAGNLLLRHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPADRD -VLNAWLRGNTTGGELIRAGVPDGWVVGDKTGAAGYGTRNDIAVLWPPDRAPVVLAVLSSR -DEPDASFDNALIAEATEVVLA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL WC-3742 TaxID=1463934 RepID=UPI000D13EEB3 ----TARHLADLEREHGARLGVHARNLRTGHVV-QHRAGELFPMCSVFKTVAVAAVLRDLD -RDGEFLARRLHYTRADTEAGAPVTGQNLAEGMTVAELCAAAIDHSDNAAANLLLRELGGP -AAVTRFCRSIGDRTTRLDRCEPDLNSAEPDRTTDTTTPRAIARIYRRLLLGHALPPAKRH -RLTTWMLGNTTSTHRFREGLPADWRLADKTGTGSYGTTNDVGIAWTPDGAPVVLSVLSTK -PDPKAPKDDALVAEAAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JT32_9ACTN ---KAEREFARLETEFDARLGVYAIDTGSGRTI-THRADERFAFVSTYKALIAAAVLDETS ---TAGLNKVIRYFKEDLVSHSPITEQHVQTGMTLRAVADAAVRYSDNTAGNLLFKQLGGP -NSFERALRGIGDQVTESARLETGLNEAIPDDERDTSTPRALASDLRAYAVDTALSRDDRT -ILTEWLTGNTTGASLIQAGVPAGWQVGDKSGAGGYGTRNDIAVVWPPKGAPIVLAILSSR -SESDATYDDALIAQAAEATI--- ->[subseq from] Beta-lactamase n=6 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9RBQ1_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1P740_9ZZZZ ---------------------------------------ERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=UPI0009E930AF -----SNRFAEIERRYRGRVGVYVPASGTAAAI-AYRADERFAICSTFKAPLVAAVLHQYP ---LAYLDQRVTFTKADITSPSPIAEQHVDTGMTVGELCDAAIRYSDNTAANLLLNRIGGP -AGLTAYLRSLGDSTSRLDQAEPELNGNPPNDERDTTTPRAIAGVFQQLVLGDALPQDKRT -LLIDWMARNTTGGKRIRAAFAADWKVSDKTGSGDYGRANDVAVVWSPAGVPHVIAIYTDM -AAYDAQPDEAFVADAARIVAS-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00073963CB -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces antioxidans TaxID=1507734 RepID=A0A1V4CZB3_9ACTN ---AATAAFTKLERSYDAHLGVYAIDTGSGHEV-AYRDGERFAYASTFKALAAGAILRKYK ---LSGLDRVIRYAKDDLVDYSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLLDQLGGP -KGLDATLEKLGDDVITMERPEPELSRWVPGETHDTSTPRAMAEDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGLPKDWQVGDKTGNGSYGARNDIAVVWRPHAAPLVMAIMSYR -GEKDTPFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0013DA9593 ----TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLSGAVLAKKT ---LPQMERLVRYGQEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDAIPGDLRDTSTPRALAADLRAYTLGSALPAEKRA -VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPPGGAPIALAVLSRR -DIKNAETDDALIAGAAKVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A5C6HSA2_9ACTN ---EAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -QNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae S611 TaxID=1399146 RepID=V5AG92_ENTCL -------AIARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -KGEFALSDITQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAIEYSDNTAANLVAQKLGGP -QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA -QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. Root275 TaxID=1736508 RepID=A0A0Q9DTL9_9BURK ---QWNDTLAGIEHFAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANLLLARHGGP -AGFTAFVRSLGDGTTRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTAPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR -SKAKPEQRDAAIAQVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_054 TaxID=2175632 RepID=A0A2W1TAK4_9MICO ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLATLVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -HAVERWLRRIGDRTTRVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGREPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium organophilum TaxID=410 RepID=UPI000D5C3DAB -----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAVAAVLARVD -AGRETLDRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP -AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD -RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG -STASPDACAAAYAEIARLIA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Hydrogenophaga sp. Root209 TaxID=1736490 RepID=A0A0T2ZME9_9BURK ----LQDSLREIEAMARGRLGVHIIDTATGREH-GWRSDERFLMLSSFKLLASALVLARAD -RGEESLERRIRFRQQDLVTWSPVTEKHVGGELSLAQLCEATITTSDNTAANLILASYGGP -AALTAFARRLGDTVTRHDRTEPELNRAASGEPLDTTTPRAMAHTVRKLLLGDALAPASRE -RLLQWLLANTTGGKRLRAGAPAGWRVGEKTGTAGD-DANDIGIALPPQRAPLIVTAYLAE -SATDGATRDAALASVGRLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amylibacter sp. SFDW26 TaxID=2652722 RepID=UPI00126196C6 ----VQKTVSNWEAKLGARIGVLLRDVSSDWEI-AMRADERFPMSSTFKALLCGAVLARVD -AEQEDISRLVNFQEDDLVSYSPVTEEHVQVGMSVGSLCEATITISDNTAANLLLETMGGP -KGLTDFLRKIGDATTRLDRWETELNEGTPGDLRDTTTPRAILSTLETLLLGDVLKPASAK -QLAQWMIDDQVADALIRAHLPDGWVIGDKTGAGGFGSRSIIAFLQVPDGGQYLAAIYLTE -NDADFQLRNKIVSDIGRALI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A0Q2QZX4_MYCGO -----SNRFAEIERRYRGRVGVYVPASGTAAAI-AYRADERFAICSTFKAPLVAAVLHQYP ---LAYLDQRVTFTKADITSPSPIAEQHVDTGMTVGELCDAAIRYSDNTAANLLLNRIGGP -AGLTAYLRSLGDSTSRLDQAEPELNGNPPNDERDTTTPRAIAGVFQQLVLGDALPQDKRT -LLIDWMARNTTGGKRIRAAFAADWKVSDKTGSGDYGRANDVAVVWSPAGVPHVIAIYTDM -AAYDAQPDEAFVADAARIVAS-- ->[subseq from] L2 family class A beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8GSQ4_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium radiotolerans TaxID=31998 RepID=UPI00040171C5 -----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAVAAVLARVD -AGRETLDRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP -AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD -RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG -STASPDACAAAYAEIARLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium intermedium TaxID=28445 RepID=A0A1E3SDB1_9MYCO ---DLSERFAELERRYESRLGVHVLADGDTAPI-SYRADERFAFCSTFKAPLAAAVLQRNP ---LAYLDKVITYTRDDIRSTSPITEQHVDGGMTIRQLCDAAVRYSDGTAANLLLAEIGGP -AGFTQFLRSLGDNVSRLDQLEPELNRDAPNDERDTTTPRAIAGVFQQLVLGEALPADKRG -LLTDWMVRNTTGDKRIRAGFPPDWKIADKTGSGDYGRTNDVAVAWSPSGASYVVAIYSDC -VTYNAPYNDAIVAAAAKIVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Sciscionella marina TaxID=508770 RepID=UPI00035E9A7E ------DRLRALERAHQAHLGVYARNLRTGATA-THRAGERFGMCSTFKTLAASAIMRDRD -GDGTFLDRIVHYTDEDLVENSPITENHVRGGMRIAELCHAAICYSDNTAGNLLLRQIGGP -AGVTRFCRSLGDRVTRLDRWETELNDIAPGDPRDTTTPRAIGEDYARLALGTALDPAHRA -RLTGWLIGNTTSAKRFRTGLPDSWLIGDKTGSGAYGSGNDVGIAWTGAGTSLVLAVLTRK -HEPEAGYDDELIAEAARILAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI00052AA8FC --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE -QKKLNLNATTTVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLHQIGGP -EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSAMVELLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILNIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DA80525 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHHQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Carbapenem-hydrolizing beta-lactamase SFC-1 n=1 Tax=Serratia fonticola TaxID=47917 RepID=UPI0002604934 ------DKLKRLENDFGGRIGVYAIDTGSNKTF-GYRANERFPLCASFKGFLAAAVLSKSQ -QQEGLLNQRIRYDNRVMEPHSPVTEKQITTGMTVAELSAATLQYSDNGAANLLLEKIGGP -EGMTSFMRSIGDNVFRLDRWELELNSAIPGDDRDTSTPKAVAESMQKLAFGNVLGLTERH -QLMDWFKGNTTGGARIRASVPANWVVGDKTGTCGYGTANDYAVIWPVAHAPIVLAVYTSK -PDRNSKHSDAVIADASRIVLESf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BvitLS-983 TaxID=1838282 RepID=A0A1C4LGY1_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -QNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_046 TaxID=2175663 RepID=A0A2W0CRR1_9MICO ---AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA ---PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP -AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA -LLVGLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH -DTADAEPDDALVAAATRTAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0008406A1C ---RTRRAFDALEREFDARLGVYALDTGSGRTV-VHRPDERFAYASTCKALLAGAVLERNS ---LRQLDRLVRYGREELISNSPVTERHLATGMTLRELCDAAVRYSDNAAANLLFRELGGP -GGLQDALRALGDRVTRCDRYEVALSDGIPGDPRDTSTPRALATDLRAYVLGDTLPAGKRA -VLTDWLKRNTTGDDTIRAGAPGGWQIGDKTGTGGYGTRNDIAVAWPPGGAPITLAVLSDC -GTKDAARDDALLARAARTAF--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=Q6U8D8_BACTU -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITKKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKKDAEYDDKLIQ---------- ->[subseq from] Beta-lactamase n=1 Tax=Starkeya novella TaxID=921 RepID=A0A2W5M8N1_STANO ----FAETIKALEARSGGRLGVALLEVGGGLRL-AHRGGERFPMCSTFKALLAAAVLARVD -RGEETTDRRIEIPASAILDGSPFSSARAGADASVAELCEASMTLSDNAAANLLLPSVGGP -QGLTRFLRSIDDPVTRLDRIEPALNEAAPGDPRDTTSPAAMAATLATLVFGETLTPFSRG -ALVRWLIDARTGGKRLRAGLPPDWTAGDKTGAGPNGTTNDVAVLWPPAGQPLVLACYLTG -SALDAAGRDAIHADVARAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces torulosus TaxID=68276 RepID=UPI0006EB5061 --------LRALEEQYGARLGVYAHNVRTGETI-RHRADTLFPICSLFKTLAAAAVLRDLD -RDGEVLARRIHYTAADLLENSDVTREHLATGMTIAELCDATIRHSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRPDRA -LLTHWLLHNQTSSTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSLMSRK -FDQDATTENKLIADTAHLL---- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. 69 TaxID=2035202 RepID=A0A2M8X3T4_9BURK ----WGETLAQIERSAQSRLGVAMLDTGSGLAL-GWRQDERFAMASTFKALLAGWMLALVD -QGKERLDARVLYGRDAVVDYSPVSGPRAGDGLTVAELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDGTTRLDRTEPTLNEAAVGDPRDTTTPQAMLQTLQKLVLGDGLTPPSRA -WLQRWLRETSTGDKRLRAGMP-GWKVGDKTGTTNSGTSNDIGVMWPAGGAPVLVTCYLTE -STAKPEQRDAAIAQVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora xanthocidica TaxID=83382 RepID=A0A372ZKT7_9ACTN ---AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS ---DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLASAAIQYSDNTAANLVFAELGGP -AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLRRYVLGDVLPEGRRG -LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR -GKADATSDDALIAQATKTVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Kiloniella majae TaxID=1938558 RepID=UPI000A278888 -----VETVTGLEESIGGRIGVAVYDLQTGQNW-EYRSDEKFPMSSTFKPFACAALLTQNE -RKGETLERMVSVSKDDLVSYSPVIEKYADGGVSLRKSCEATVSISDNTAGNLVLKEIGGP -EGFTKFMRSIGDNTTRLDRWETELNEAQPDDLRDTTSPKAIATSLQKLLLEDALSPEARI -EITNWMLNDQVADDLFRSRLPKGWKIADKTGAGGFGSRGIIAVIWPPSRKAVVASVYMTG -NDADFKTRNAAIAEIGAAIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SUN51 TaxID=1828112 RepID=A0A5B0AQM4_9ACTN ---SVTRALTELERAHGARLGVYARNTATGETV-RHRAEETFPMCSVFKTLAAAAVLRDLD -RRGEFLDLRIRYTAQDLTDGSPVTGDNLAHGMTVSALCHAAIAHSDNAAANLLLRELGGP -TAVTRFCRSVGDPTTRLDRWEPELNSAEPWRTTDVTSPAAIGRTYGRLVLGDALVPRDRR -QLTEWLLANTTSTARFRKGLPADWALGDKTGTGSYGTSNDVGVAWTPDGAPVVLAVLSTK -PDPDAPKDDELVARAAELLA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas guangdongensis TaxID=1141890 RepID=A0A285QXF5_9SPHN ----FAATLADIDRRAPGRLGVAVLDFATGQRF-ALRGGERFPMCSTFKFPLSAAVLHAAD -RGRLPLDRAVAVRRGDIIANSPVTARRVGGSMRVAALCHATMTTSDNAAANLLLPLIGGA -DGFNAFLRAAGDRVTRLDRIEPHLNEGTPGDPRDTTTPAAMLATMRATLFGSVLSAASRQ -RLIGWLVANTTGGRRLRAGLPAGWRVGDKTGTGET-SANDIGVLWPPGRAPILVASYLTE -ARGSQVRRYAVHAEVARAIA--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus sp. RU2C TaxID=1907304 RepID=A0A1N7AU03_9BACI ---TIERKLAKLEDTYDAKLGVYALDTGTNKVI-SYRPDERFGYASTHKALAVGVLLQQKD ---IKDLDKRITYTRDDLVNYNPVTEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP -IGFKKALRELGDNVTNPVRMEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE -LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR -NEKDASYDDKLIAEATKEVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus salarius TaxID=284579 RepID=A0A428MRM1_9BACI ---NTDEKFAQLENDFDAQIGVYAIDTGSNQTI-EYRPEERFAFTSTYKALAAAIVLKQNS ---MEELKEVITYTEDDLVSYSPVTKNHVDTGMTLLELSEAAVRSSDNTAGNFLFKKLGGP -DEFEQALRQIDDNVTQADRYEPDLNEFTPGDTLDTSTPIALANNLQAFAVGDLLSDEKRE -LFTDWLQGNATGDTLIRAGAPEGWNVGDKSGAGSYGTRNDIAVVRPPNREPIVIAIMSRH -DTEDAKYDDKLIAQVAEET---- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_008 TaxID=2175656 RepID=A0A2W1V286_9MICO ---AAERAFAALETEHDARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA ---PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP -AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLGGALDPDDRA -LLVDLMRGTTTGAGTIRAGVPEEWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH -DTADAEPDDALVAAATRTAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium TaxID=1763 RepID=UPI0007EF558C ---DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRAEERFALCSTFKAPLVAAVLHQYP ---LSYLDQRVTFSKADISSPSPIAEQHVDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP -AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRA -MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI -AGYDAQPNEAFVADAARIVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. OK095 TaxID=1882760 RepID=A0A1H8BKX4_9BRAD -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLASMIPYGKADLLEYAPVAKQNLSAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTISRLDHNEPELNRSPPGDPHDTATPAAMASNLKRLVTGEALSGASRA -QLTEWMVGCKTGANRLRGGLPAAWTIGDKTGNNGKDASGDIAVVWPKPDRPILIAAYTQG -GTPTSAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis mediterranei (strain U-32) TaxID=749927 RepID=A0A0H3DBE3_AMYMU ------PDFAPLERSFDARLGVYALDTGSGREI-THRADERFGYASTHKVFSAGAVLRRTS ---LDGLAKNLTYTRADLQPNSPVTEKHVTTGLSLREAMDATLRYSDNTAANLLFRELGGP -AGLAAALREIGDTTTHADRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQT -VLTDMMRANTTGAALIRAGAPAGWAVADKTGSGSYATRNDIAVVWPPGRAPIVLIVMSSR -QAESADHDDRLIAQAAKLALDAf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium stylosanthis TaxID=1803665 RepID=A0A560EC01_9BRAD -------ELETYERESGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSQASRV -QLTDWMVNCKTGANRLRGGLPSSWTIGDKTGNNGKDASGDIAVVWPKPDAPILITAYTQG -GSPTAPQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium canariense TaxID=255045 RepID=A0A1X3FMV4_9BRAD ---DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLLTGEALSATSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIATYTQG -GTPSAAQIEAVFARIGRIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D6AZL5_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRILYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia sacchari TaxID=1158459 RepID=UPI00080751EA -------AVARLEEHLGARIGIAVIDTASGETV-SYRGDERFPLNSTHKALLCGVLLSKVD -KGELALNETTQFSQSELVAYSPVTSKFVAPSMSWQQLCSAAITESDNTAANLLAQKLGGP -AAVTRFFVDSGDSVTRLDRAEPELNSAVPGDVRDTTTPLAVSHTLQKLTLGEVLTPRSRA -QLVQWMKEDKVADALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD -TKATIAQSNDAIARIGKAIFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM49041 TaxID=2603216 RepID=UPI0011F09678 ------GRLRALERKHDARLGAFAYDTGTGRAV-RYRADELFPMASLFKTLAAAAVLRDLD -RDGEVLAKRVHYTARYVEDYSPVTEQNIANGMTVGELSAAAICRSDNTAANLLLRELGGP -TAVTRFCRSLGDGTTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYARLVLGDALAAHDRE -RLTDWMLANTTSEARFRAGLPEGWLLADKTGGGGYGGNNDVGIAWPPGRPPVVLAVLTTK -FEADAKADNPLVAKAAEILAE-- ->[subseq from] Beta-lactamase n=1 Tax=Marininema mesophilum TaxID=1048340 RepID=A0A1H2S3R5_9BACL ---TITKDFYQLEDKFNAKLGIYALDTGTGQTV-TYRSDERFAYASTHKALAVGALLQQKS ---IKDLDQKITYTRDDLVSNSPITEKHVDTGMTLKELSDASLRYSDNTADNLILKQLGGP -SGFKKSLRKMGDKVTNPKRYEPELNDVKPGEIRDTSTPRALATTLQAFTLGDALPAKKQG -MLVDWMKRNTTGDALIRAGVPDNWEVADKTGGAD-GIRNDIAIIWPPKKDPIVLSILTRS -RDKSSENNDKLIAQATKKVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter capsici TaxID=435897 RepID=A0A0S2FW37_9GAMM ----WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE -LGKVALSQQVPITAADMISHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP -QGLTRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ -QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPILIVSYLAT -AKLDGAGRDAVLASLARIVSK-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C15C443 -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMSVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI00143853E7 ------------------------LDLNSGKILdSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces brevispora TaxID=887462 RepID=A0A561TUH3_9ACTN ---RTERAFRELERKFDARLGVYTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLDKNS ---VRQMDRLVRYGREDLVEASPVTERHVATGLTLRELCDAAVRYSDNTAANLLFHELGSP -GALQDALRVLGDNVTRCDRYETALSDATPGDLRDTSTPRALATGLCAYVLGSTLPADKRA -VLADWLRRNTTGDTTIRAGTPDGWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR -RTKDAERDDALIAQAAKVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter salarius TaxID=1420917 RepID=UPI000F85468C ----LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD -NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIDGP -DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD -TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ -TGASFDERNGAIRDLGGAIVKHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB73_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVMLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C7C983 ------PRLAALERKYDARLGVYALATGTGATV-THRADERFAFCSTFKGMAAAAVLHRHP ---LSYVSTVVTYTEADLMKHSPVTRKHVATGMTIRQLCDAAVRFSDGTAGNLLLREIGGP -GALTAFTRSLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGNVLAADKRA -FLRDLLERNTTGAERIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK -STKDAAYDQALIADAAAYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Inquilinus limosus MP06 TaxID=1398085 RepID=A0A0A0DBY2_9PROT ----AAARLAELERAHGGRLGVAALNLATGARI-GYRADERFLLCSTFKALAAAFVLARVD -RKQERLDRRIAFSRKDIVAVSDVTKPRVGGAMTVAELCDAAVTHSDNTAGNLLLASFGGP -AGLTAFLRSLGDEASRLDRIEPELNAAGPGDPRDTTTPAAVLETLRKLLFGDALSAASRH -RLAAWLITNKTGDARLRAGFPAGWLVGDKTGTGGEGSTNDIAVAWPVDRGPVLVAAYCEL -PSLTFEQRNPVVAEIGGIVA--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Rhizobiales (miscellaneous) TaxID=41292 RepID=A0A259CD15_9RHIZ -------AFAPLEAKTGGRLGICVLDGAGGIIA-AHRAQERFAMCSTFKLLLAAAVLARVD -EGRERLDRRITYTAADPVGHSPVTRQNVAEGMTVGELCAATVALSDNGAANLLLATLGGP -EGLTAFLRRTGDTVTRLDRWELALNSAIPGDPRDTSTPAAMAGSIRRLVAGTVLKPASRT -QLRDWLVATKTGDTRLRAGLP-GWHVGDKTGTGNNGTVNDVGFALAPGADPVVMVVFLTK -SRLDVEASSGIIADVARQVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=A0A1Q4VIF0_9ACTN ---AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS ---DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLASAAIQYSDNTAANLVFAELGGP -AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLRRYVLGDILPEGRRG -LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR -GKADATSDDALIAQATKTVVS-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010202172 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -QNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas terrae TaxID=405446 RepID=A0A0R0CLX2_9GAMM -------DFAALEKASGGRLGVCLWHPASGARY-GHRMDERFPMCSTVKFPLAAAILHRVD -AGKLSLDQRVAVRQGDIISHSPFTGRHVGKDMTVRDLCRATLIISDNAAANLLLPLIGGP -AGLTAFLREHGDRITVSARNEPELNRFAPGDPRDTTSPAAMAGNLQRFLLGDVLSPASRQ -QLADWLIDNQTGDARLRAGLPQGWRVGDKTGSNGQDTSNDIAVLWPLGGPAWLLSCYLQG -SALDDDGRDGILRQVGELA---- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus poinarii G6 TaxID=1354304 RepID=A0A068R5F7_9GAMM ---EIIHQLSNLEKESNGRLGVVLIDTSDHSTI-TYRANERFPLCSTSKLMAVSALLKKSE -TNAHLLNQRVHYQQSDLIEYSPVTEKHLKDGMTFGELSAATLQYSDNTAMNLLLNQLNGP -HEVTKFARTIGDNHFRLDRPEPALNSAVPGDKRDTSTPQAMADSLYHLALGHALATTQRE -QLTVWLKGNTTGNTSIRAGVPNDWLVGDKTGRCDYGTTNDIAVIWPTKRTPLVLATYFTQ -PEKEAHPRPDVLAAAARIVTQ-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. B29(2018) TaxID=2485016 RepID=UPI000FD68236 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces fradiae TaxID=1906 RepID=Q59911_STRFR ---RVEGRLRALERTHDARLGAFAYDTGTGRTV-AYRADERFPIASMFKTIAVAAVLRDLD -RDGEVLARRVHYTADYVKRYSPVTGENVANGMTVAELCEATLTRSDNTAANLLLHDLGGP -TAVTRFCRSVGDHVTRLDRWEPELNSAEPGRVTDTTSPRAIGRTYGRLILGDLLAAHDRE -RLTRWMLDNRTSDERFRKGLPADWLLADKTGGGDYGTNNDAGVAWPPGRPPVVLAVQTTR -FTPDAEADNVLVAEAARLLAE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00056D90F3 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ScaeMP-e48 TaxID=1100823 RepID=UPI000823951D ----TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKRS ---LPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGSALPAEKRA -VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKVALEAf ->[subseq from] Beta-lactamase L2 n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A0K2ZFA9_XANCT --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDALQPASRQ -QLSAWMLDNRTGDACLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRMPLLLTAYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. GF20 TaxID=2692235 RepID=UPI001317D684 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Terribacillus sp. 7520-G TaxID=2025389 RepID=A0A268BQQ5_9BACI ---DAQEPFADLEKAYDAHLGVYAIDTGSGKTA-AYRENERFGFASTHKALSAAVLLQQNS ---LKDLDKKIMYTRDDLVNYNPITEKHIDSGMTLKELGEASVSYSDNTAANLIFEEIGGP -DGLKQALRDIGDQVTEPSRIEPELNNVKPGETQDTSTPKALAESLRAFTLGDSLPAEKRQ -LLIDWLKGNTTGDALIKAGVPEEWEVGDKTGAGAYGTRNDIAVLWPPDSDPIIMAVMSSR -DEADAKYDDALIAKAAEEAV--- ->[subseq from] Beta-lactamase n=2 Tax=Actinopolyspora sp. DSM 45965 TaxID=2586995 RepID=A0A543JXJ3_9ACTN ---EVGERFDRLEQRFDARLGVYAVDTATGEEV-THRADERFAYASTHKALSAGVVLRRNS ---IGGLNRRIHYSASDLVTYSPITKEHVDTGMTLRGVMDAAIRYSDNTAANLLFRELGGP -AALQDALRGIGDTTIHVDRVEPELNRTSPGDIRDTSTARAMAESLRKFTTGDVLSADKRA -ILNEMLRTAKLTGDLIRAGVPSDWEVGDKSGAADYGTRNDVAVIRPPGRAPIMLAVMSDR -QDEDADYDDALIAQAARHVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter methanicus TaxID=1774968 RepID=A0A1E3VWZ2_9RHIZ ---ALTRRFSEIETAVGGRLGVAVSDPGTGLAA-ELHGDERFPMCSTFKLLAVAAVLNRVD -KGEETLSREVPVPKSAILSYAPVTEKHAGGVLSLSDLCAAAMVWSDNTAANLVLETVGGP -EAATAYVRSLGDDVTRMDRMEPALNDVGPGEVRDTTTPNAMLGNLDKLFVGDALSPLSRD -LLTEWFVGCKTGTARLRAGLPETWRVGDRTGTGPHGTSNDVAVAWPTGPDPILIAAFLTG -SKADETERDAALADVGEAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Shinella sp. HZN7 TaxID=879274 RepID=A0A1A9FXK1_9RHIZ -----AQRLAALEARHGGRIGVAILNLATGARL-GHNTEERFLMCSTFKALLAGHILARVD -RGEETLDRRIVVKEADLVDWSPVVEKRVGGEISIAELCEATITLSDNAAANLLLAASGGP -KAVTAFLRGFGDTVTRLDRTEPTLNYEAPDDERDTTTPTAMVETLRRLLFAEVLSARSKA -QLAAWLVMNKTGDTRLRAGFPPGWMTGDKTGTNGAGNANDVAVAWSPDRGAVIVAAFCEI -PGISGDARNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. I6 TaxID=2483113 RepID=A0A3N0D6Y3_9ACTN ------RGLAALERTYSARLGVFARNTRTGRTV-SHRAGELFPMCSVFKTLAVAAVLRDLD -RRGEFLTRRIHYTEKDTEEYAVITQENLANGMTVAGLCDAAIRYSDNAAANLLLRELGGP -SAVTRFCRSLGDGVTRLDRWEPRLNSAEPWRVEDTTSPRHIARTYSRLVLGDALSRPDRQ -RLTGWLLNNTTGKERLRAGLPGDWTLADKTGAGEYGTNNDVGIAWTPDGSPVVLAVLTTR -RHPDAAPDNQLVARTAELLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium oryzae CBMB20 TaxID=693986 RepID=A0A089NX68_9RHIZ -----EPDWGALEHRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAAAAVLARVD -TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP -EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG -RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSVNDIAILRPPGRAPVVVAVYVTG -STASAETYAAAYAEIGRLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. B006 TaxID=2201999 RepID=A0A385B1X4_9ACTN ------AELAALERRFGARIGVYAVDTGTGRTL-AHRADERFAYASTCKALAAGAMLAATS ---DADRDRVLRYRRADLVAHSPVTERHVDTGITLRDAAEAAVRHSDNTAGNLLFDALGGP -AGFARALRDVGDRVTRPVRTEPELNAATPGDTRDTSTPRALVGSLRAYTLGEALPPADRD -LLLGWMRASTTGSALVRAGTLAGWQVADKSGTGGYGTRNDIAVVWPPDRAPIVLAVLTSH -DSRGAKPDDALVAQAARATV--- ->[subseq from] Beta-lactamase n=1 Tax=Shinella granuli TaxID=323621 RepID=A0A4R2D1R2_9RHIZ -----AQRLAALEARHGGRIGVAILNLATGARL-GHNTEERFLMCSTFKALLAGHILARVD -RGEETLDRRIVVKEADLVDWSPVVEKRVGGEISIAELCEATITLSDNAAANLLLAASGGP -KAVTAFLRGFGDTVTRLDRTEPTLNYEAPDDERDTTTPTAMVETLRRLLFAEVLSARSKA -QLAAWLVMNKTGDTRLRAGFPAGWMTGDKTGTNGAGNANDVAVAWSPDRGAVIVAAFCEI -PGISGDARNAVIAEIGRIAAE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0004BF302D ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus group TaxID=1477431 RepID=UPI000833D88E ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus beddingii TaxID=40578 RepID=A0A1Y2SMB6_9GAMM --nQLTHQLSMLEKNAGGRLGVVLIDTFDHSTT-VYRANERFPLCSTSKLMAVSALLKQSE -TSGHLLSQRIHYQSSDLTEYSPITEKHLKDGMTLGELSAATLQYSDNAAMNLLLNQLGGP -HEVTKFARTIGDHHFRLDRKEPELNTAIPGDERDTSTPQSMANSLYHLALGNILATIQRE -QLVGWLKGNTTGGASIRAGVPKDWVVGDKTGRCNYGTTNDIAVIWPTNRSPWVLVTYFTQ -PNQNASARPDVLAEAARIMIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CT2-14 TaxID=2675850 RepID=UPI0012B96731 ------AALRALEQQHGARVGVVAIDTGTGKTL-GYRQDERFAFDSTFKPLACGALLHAHP -LNSGFFDQVIHFGADKLVPNSPITSTRLDTGMSVAELCEAAITRSDNTAGNQILELLGGP -QAVTAFLRSIGDRTTRMDRWETELNTNIPGDERDTSTPAVLADDYRKLVLGDTLPEPERT -QLTTWLLANTTGDARIRAGLPADWKTADKTGSGDYGTANDIAVTWPASGAPLVIVVLTTK -PDQAAPADNPLVAALAKEAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus sp. KK7.4 TaxID=1851572 RepID=A0A2D0JZQ5_9GAMM ---QIIKQLTTLEQSANGHLGVVLINSADNSTI-GYRTNERFPLCSTSKFMAVSALLKKSE -TDENLLKQRVNYKQSDLVEYSPITEKYIETGMTLAELSAATLQYSDNTAMNLIINQLGSP -ESVTTFARTLGDTMFRLDRKEPELNLVQPGDKRDTSTPQAMAESLYKLTLGDSLAPKQRT -QLVEWLKGNTTGNASIRAGLPKDWVVGDKTGRCDYGSTNDIAVIWPSNRAPLVLVTYFTQ -PGKNAKARPDVLAEAARIIIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI0004919318 ------RDFAALEAASGGRLGVSLLDTASGQAR-GHRQDERFPMCSTFKALLSAAVLAGAD -RGRWSLDRRLAVGEGDLVPHSPVARRHVGKDLTVRDLCRATMTTSDNAAANLLFGLIGGP -SALTAFLRANGDTVTRNDRLEPVMNAFAPGDPRDTTSPRAMAASMARFAVGDALAAQSRR -QLADWLIDNGTGDACLRAGLGPGWRVGDKTGSNGVDTRNDVAVLWPRDGTPWVLAAYLQG -ATVDSDARDAVLARVARLA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L4FMQ3_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTD-VTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATM------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cavernae TaxID=2259034 RepID=UPI000FEBACA1 ----TSRKWAALERQHSARLGVFALDTATGATV-RHRAGELFPVCSVAKTVAVGAVLRDLD -RDGEFLARRIRYTAADVENHAPITGEHIADGMTVAELCAAAITHSDNAAMNLLLRELGGP -TEVTRFCRSIGDPTTRLDRYEPDLNSAEPWRVADTTSPLAIARTYARLTLGDALEPKDRA -QLTGWLLANTTGANRLRAGLPADWTLAEKTGTGDYGSTHDVGIAWPPHRAPIVLAVLSTK -ADAEAPADEPLLAEAAGLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI0009FBD38E -------SFAEMETTHSARLGVYAIDTGTGRTV-VHRDGERFPIASTFKGLACGALLREHP -LATGYFDQVIHYSRPELVANSPVTEKHVDTGMTVAELCDATITLSDNTAGNQLLKLLGGP -EGFTAFLRSIGDTASRLDRWEPELNTAVPGDERDTTTAAALATDYRNLVLGDILAEPERA -RLKSWLVAAKTGGARIRAAVPADWTVGDKTGSPAYGGALDVAIAWPPGRAPLVIAVLSTK -FEQNAEADNSLVAEAARAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Paenibacillus TaxID=44249 RepID=UPI0007AC008A ------VVFKQLETKFDARLGVYVIDTGTGKEV-AYRADERFAYASTYKALAAGAVLQQKS ---NDELGKVIKFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGNTVVMANRYETELNEAIPGDLRDTSTPNALANSFKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPDREPIIIAVMSSR -DTEDAEYNNTLVAEAAKAAFK-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066DA740 -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAINYEQRASVLAHVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A5B0W2Q0_RHITR -----EARLAAIESKHPGRICVSILDMASGKHI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIRYSEGDIIGGSPATKLHVGDGMTVAELCAAAVTLSDNAAANLLLASFGGP -KALTAFCRSLGDEITRLDRIEPALNYDAPDDQRDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGVPRDWLVGDKTGTNGAGNANDIAVLWPSNRAPIIVTAYCEV -PSISADERNAVIAEIGRIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBV6_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPITRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=UPI0009A25617 ---AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS ---DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLASAAIQYSDNTAANLVFAELGGP -AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLRRYVLGDILPEGRRG -LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR -GKADATSDDALIAQATKTVVS-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A1B2N773_9GAMM ------ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSATVLHLAD -QGTLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGEVLTPASRL -QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLASYLQG -ATVDDAGRNDTLRQVAVIA---- ->[subseq from] Beta-lactamase n=1 Tax=Mesorhizobium sp. B2-3-3 TaxID=2589960 RepID=A0A504D5A6_9RHIZ -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRAGTPASWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK340 TaxID=2572903 RepID=A0A559U8Y5_9ACTN -----HTELSDLERRYGARLGVFARNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDRG --GCAPLDKVINYPPSDILPNSPRTEEHLATGMRVGDLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAIPGDLRDTTTPEAVGRSFERLTLGRALDGAGRE -QLVTWLKGNTTSARRFGAGLPRGWVLGDKTGTGDYATANDIGVAWTTRGTPVVLAVLSTK -AEKDAPVDEALVADTARVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Cra20 TaxID=1327635 RepID=A0A2K8MFL2_9SPHN ---DFRKAVRAVEQTSGGRLGLSVIDLASGERF-GWRASGRFPMCSTFKFALAAAILKQVE -HKHENLNRRISVVAGDIVSLSPFCEQRVGTTASVRELCHATITLSDNSAANLLLRTIGGP -EGFTRRLRAFGDPATRLDRWETAMGEARPGDVRDTTTPEAMADLARQLVLGRALAPASRA -QLVAWMKDTRTSAKSLRAGLPADWTVADKTGAGGFGTDNLVGIVWPPHRAPLVVASYITG -STLEFEQRRPLHAGIGRALA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A264Z2G6_9BACI ---TIERKLAKLEDTYDAKLGVYALDTGTNKVI-SYRPDERFGYASTHKALAVGVLLQQKD ---IKDLDKRITYTRDDLVNYNPITEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP -IGFKKALRELGDDVTNPVRIEPELNDVQPGEIADTSTAKALATSLQAFTLGDALPVEKRE -LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR -NEKDASYDDKLIAEATKEVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. EKM101V TaxID=1683695 RepID=UPI00142E4350 --qSLNNQFEKLERQSGGRLGLAVIDTSDSVQY-SWRGNERFPLCSTSKVMAVAAILKKSE -NADTLLNKKIYISQHDMVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QYATQFARTLGDTMFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGPALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759945F ----ALDSIRSIEMSRGGRLGVAVLDTGSGRRL-RYRADESFAMCSTHKFLSAVAVLSLVD -QGKLALDKPVKYGKADLLDYAPVARERVGRGMTIDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRG -RLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPHASPILAAIYYTE -STGSLASREEVIAEVGGIIAKTf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI00142869CF -----AAELSALEQQYGAQVGLFAVDTGSGKTV-TNRADQRFPFLSTFKGLAAAALLKAHP -LDTGYFDRVIHYTEANLVDYSPVTGAKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP -QGLTDFLRTIGDQVGRLDRWEPDLNTAYPDDERDTTTPAALAAAYRALVVGDALGAPERD -QLTKWLKANTTGDKRIRAGLPAGWSTGDKTGTGSYGMANDVAVTWPENQSPIVIAIQTRK -PTETADPSNDLVAATTKLALTH- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. DG1229 TaxID=681847 RepID=UPI0012EB3538 ----VAKAIEDIETRLSARVGVSIIDTESGKTW-SHKGNERFPMNSTFKAFLCAALLDAAS -NRTVDAGREVVVEESDIVSYSPVTAKRVGGAFTIEDLCRVTVTISDNAAANIVMKEVGGP -EGVTAYLRGIGDDMSRVDRWEPESNTGIPGDDRDTTTPDAAAETLRKLVLDETLAADARA -KLTGWLEGNKVGNSTLRAGLPEGWRIADKTGAGANGSRNNIAVIWPEGRKPLVIAIYITQ -TTAAFEARNKAIAGIAQAL---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. ACS1 TaxID=2028570 RepID=A0A2A3F764_9NOCA --qSLDAKIEALEAQYATRIGVTAVYPATGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE -DGSTALDKTVVIEPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAVTALARDLGDESTRLDRWETELNTAFRGDPRDTTTPTGLARGFRALLLDDALDAASRD -QLLEWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPIVLAVLTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria MEX-5 TaxID=396597 RepID=B1T5K0_9BURK ----ALDAIRSLETSHGGRLGVAVFDTGLRRRL-QYRADESFAMCSTHKFLSAVAVLSLAD -QGKLDLDKPVKYGKTDILDYAPVAKKHVDRGMTVDELCAAATVWSDNTAANLLIELLGGP -AGWTRFARSIGDNASRLDRTEPALNSAIPGDPRDTTTPDAMLANLQQTLLGTVLSDSSRE -KLQNWMLSGTITDTLLRAGVPLTWRVGDKSGAGRNGTRNDIGIIFPPNASPILAAIYYTE -STGSLASREEVIAGVGGIIAKTf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseocarneus TaxID=51201 RepID=A0A3L8KF06_9ACTN ------GRLRELEREHSARLGVFAHDTGTGRTV-LHRADERFPMCSVFKTLAVAAVLRDLD -HNGEFLAKRVRYSADYAKAWDPVTGKNVANGMTVGELCDAAIRFSDNAAANLLLHELHGP -GTVTRFCRSLGDRTTRLDRWEPDLNSAEPWRETDITSPRAIGETYGGLVLGDALDRRDRA -RLTGWLRGNTTGTERLRKGLPADWTVGDKTGAGSYGTNNDVGIAWPPGRAPIVLAVLTTK -HEHDAKGDDPLVAKAAELVAK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2AG32_STRVZ ---ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD -HDGTFLARRIWYTAADVKRWSPRTEENLARGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHRDRE -RLTRWMLANTTSGERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR -SLEDAPVVDPLVAEAAALVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium TaxID=374 RepID=A0A1Y2JDE4_BRAJP -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKVPILIAAYTQG -GRPNAAQIEAVFARVGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sporosarcina koreensis TaxID=334735 RepID=UPI0009E7C56B ----IDEKFSQLENEFDAQIGVYAIDTGSNETI-EYKPEERFAFASTYKALAAAILLQQNS ---LEDLKEVITYTEEDLVTYSPITEKHVDTGMTLLELSEAAVRFSDNTAGNLLFEALEGP -KGFEQALREIGDNVTIADRFEPDLNNFTPEDSRDTSTPKALATSLQAFAVSDLLSDDKRE -MFTDWLKGNATGDKLIRAGAPKGWEVGDKSGAGAYGTRNDIAVVWPPDRAPIVIAILSKH -NTVDAKYDDKLISRTAEIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. IgraMP-1 TaxID=1839767 RepID=A0A1C4I800_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus koreensis TaxID=99653 RepID=A0A1H5CIC6_9NOCA --qSLDAKIEALEAQYATRIGVTAVYPATGAVY-SHRGDERFAMCSTFKAYASAAVLRKIE -DGSTALDKTVVIEPGDLVENSPVTTAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAVTALARDLGDESTRLDRWETELNTAFRGDPRDTTTPTGLARGFRALLLDDALDAASRD -QLLEWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWSPDGSPIVLAVLTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia uniformis TaxID=53432 RepID=UPI00082B21DD -----DTRLTDLERQHDARLGVFAIDTGSGTTV-GTRQDERSPMLSTFKTLACAALLRAHP -LSTGYFDQIIHFTEADAAAYSPVTGKRIDTGMSVLELCDAAITYSDNAAINEVLKLLGGP -QAVTEFARSIGDEVTRLDRWEPELNTAMPGDERDTTTAAAIAGDYQALVLGDALPEPERQ -QLTEWLRANTTGDSRIRAGLPGDWQTGDKTGTSGYGTANDVAVTWPADGAPIVIAVLSTH -ATESADPDDALIAEATKAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Oleisolibacter albus TaxID=2171757 RepID=UPI000DF18CD1 ---AIRSAIADLETRSGGRLGVAVRDMSSGEAV-DWRGEERFPLCSTFKLPATALVLSRVD -RGQERLDRIVPYGTADLIDYSPVTAPHAGTGLSMEALCQGAMILSDNTAANLMLDSFGGP -AALTAFLRDLGDGVTRIDRREPEVNIVPPGEVRDTTSPLAMLHTLERLTLGDSLSPTSRA -RLVGWLIDNRTGDKRLRAGLPAGWRAGDKTGSWDKGTANDVAILWPPGGGPLLVTAYLTE -APGGNDGRNRILAAVGRLVAGG- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WQI7_PSEUU ----AAADFATLEAAAQGRLGVAVLDAGSGRHLgGHRPEERFPMCSTFKAMLSAAVLAQAD -RGALSLDERLPVGEADIVSHSPVTRRHVGKDVTVRDLCRATMTTSDNGAANLLLGRIGGT -AGLTAFLRGIGDRVTRSDRMEPEMNAFAPGDPRDTTSPRAMAGSLARCVLGDVLSPASRM -QLADWLVDNGTGDDCLRAGIGPGWRVGDKTGGDGAGTRNDIAVAWPLQGSPWVVTAYLQG -AKVDSPSRDAVLARAGALAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia amikacinitolerans TaxID=756689 RepID=UPI000A03AC7E ------EHLIELERKFDARLGVYALATGTGATV-AHRADERFAFCSTFKGLVAAAVLQRNP ---LSHLDTVVSYTEADLLKNAAVTPKHVDTGMTIRDLCDAAVRFSDGTAGNLLLRDLGGP -AELTAYARSLGDTITRMDRTEPAITQAVPGDLRDTTSPRALGTDYQQIVLGDALPADKRA -FLRDLLERNTTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIGVVWPPNSAPLVLALMSSK -ATPDAPYGQALLAEAAAYVVD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LSG3_ECOLX -----------------------------NAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium radiotolerans TaxID=31998 RepID=A0A438LRQ3_9RHIZ -----EPDWTAIERRLGGRLGIAAGS-ADRALA-AYRADARFPMCSTFKVLAVAAVLARVD -AGRETLDRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP -AALTAWLRTTGDPVTRLDRTEPALNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD -RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG -STASPDACAAAYAEIARLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012FE3682 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEAVRVGPLHQKQTLPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudolabrys sp. FHR47 TaxID=2562284 RepID=UPI0010BF0D0D -----AQRVAALEKKIGGRVGVYLRDITGRVLV-AHRADERFPMCSTFKFLLAAAALKRVD -QGQMSLDQILNFGEADLLSYAPVAKANVAKGLPLAELCAAIVTVSDNTAANVILRNIGGP -QAVTAFARSIGDQDTRLDRNEPDLNSAIPGDPRDTTTPQAIGEDMPRLLSGNALGAASQQ -MLENWMVASKTGLKRVRAGLPNGWVVGDKTGSGANGSANVVAVIRPGNRATLFASVYLTG -SSAPAEELDAVHTEVGRIIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00039C4D80 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-CYQVDERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKEIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWIVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASSDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CNPSo 3424 TaxID=2560056 RepID=A0A4Y9LA24_9BRAD -----PAELESYERESGGRVGLHAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMVPYGKADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDNTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGDALSPASRA -LLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDAAGDIAVVWPKPDTPILIAAYVQG -GAPNAAQIEAAFARIGRTVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CT34 TaxID=1553907 RepID=UPI0005BCB044 ---DTTARFAALEGTYRARLGVYAVATGTGATA-SYRADERFALCSTFKPLAAAAVLHHTP ---SGRLDRRVTYTAADVNSISPITKDHIATGMTLRQLCDAAIRYSDGTAGNLLMRDIGGP -AQLTAYLRQLGDTTSRMDHYEPELNRVRPGDPRDTTTPRAIAADYRELVLGDALTADRRA -LLGDWLERGTTGARRIRAGLPRGWRVADKTGTGDYGRANDIAVVRPPHTSPLVVAIMSDR -AGYSTPPQDALIAATTKLLV--- ->[subseq from] Exo family class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1QB46_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Franconibacter helveticus TaxID=357240 RepID=UPI000DA211EF ---ALTAAAQQEEKTLNARIGVTVLDTATGKTL-SYRGDERFPLNSTHKPLLCGALLKQAQ -EKKIRLTDSVLFDKSQLVDYSPVTEKHVSPQMNWLQLCSAAVSYSDNTAANLISQKAGGP -QAITAFVRASGDNITRLDRFEPELNEARPGDERDTTTPDAISHTLQKLLLGDVLSEASRQ -QLTRWMAEDKVADALLRKSLPKGWKIADKTGAGGYGSRSIISMVWPEKGAPMVVAIYITR -TEASLTQSNDAIARLGGVIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SAI-083 TaxID=2485146 RepID=UPI000F514660 ----VAARLRALEERYDARLGVFAHHVPTRRSV-RYRADERFPMCSVFKAVAAAAVLRDLD -RHGEVLARRIHYTEDDLVIGSDRTAEHLAEGMTIAELAEVAITYSDNTAGNLLLRELGGP -TAITRFARSLGDGVTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALERRDRE -LLTHWLLSNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTGDGDPIVLSVLSTM -PEPDAVRDDALVADAAAVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizomicrobium palustre TaxID=189966 RepID=UPI0014223580 ------AAVTLAEKTSGGRLGVAVIDTGSGARF-SYRGSERFPLCSTFKLLLVTAVLCKVD -AGAESLERRVAVKKGDILGNSPFSAQHVGTSASLGELSEATITLSDNTAANLLLPAVGGP -EGLTKFLAEMGDSVTRIDRYEPIMSSSIAHDLRDTTTPEAMAATVQKFVLGTVLKPASLA -LLQAWLRATKTGSNRLRAGLPADWQVGDKTGTGDHGTSNDVAVIWPPHRAPLVVASYVNE -SKLSDRATQHIHAEVGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. 2SA TaxID=2502198 RepID=UPI0010F86B6F ----ADSAFTQLEDDFDARVGVYAVDLDTGREI-AWRADERFAYASTIKAMASAALLDEVG ---TDGLSKDIAVDEDDIVSHSPVTETNVGGTMTLAELCEAAMTQSDNGAANLIVAELGGP -ASLDSRLDDLGDTGTTVSRTEPDLNEATPGDPRDTTTPRASASNLREYVFGGVLSDDEAT -TLTDWMKATQTGDTLIRADLPEEWTVGDKSGTGSYGSRNDLGIIWPDDGRPIVISVLSSK -KEKDAEADDRLIARAAAAAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Orbus hercynius TaxID=593135 RepID=A0A495RK67_9GAMM --qATLDKIKAVESQLNTRVGYAELDFNSGLMLeSYRATERFPMMSTFKVLLCGAVLSRVD -SGLEHLDRRIVYHPNDLITYSPVTKDHLSEGMSVAELCSASITMSDNTAANLLLSTIGGP -HALTQFLREMDDPVTRLDRIEPMLNQSLPNDERDTTTPEAMAITLHKLLTGNTLTQTSKQ -QLIDWMVADKVGGPLLRSVLPDGWFIADKTGAGERGSRGIIAVLGPDDKPARIVVIYLTG -SWANMNQLNEQIAAVGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. CBEL-1 TaxID=2502980 RepID=A0A4R4JEG0_9BACI ---TIERKLAKLEDTYDAKLGVYALDTGTNKVI-SYRPDERFGYASTHKALAVGVLLQQKD ---IKDLDKRITYTRDDLVNYNPITEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP -IGFKKALRELGDDVTNPVRIEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE -LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR -NEKDASYDDKLIAEATKEVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=UPI0013EE68B2 ---QYNSSFSQLESDYGVKLGVYAFDTETHKEV-VYRADDSFAYCSTFKALAAGAVLKQDS ---LEQLKQVVKYNKEDVLSYAPITKDNVDKGMTIEELCNAAVRFSDNTAANLLFDHIGGP -NGFKSSLNQLGDNVTQPTRIEPDLNEAIPEDIRDTSTPRQLATDLQAYTTGDILTDDKKK -ILIDWMTCNATGNTLIRAGAPEGWVVADKSGSGSYGTRNDIAIVMPPNKKPIIIAILSTH -DTKEAKHDDELIAQASKIVFDSf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_O1-15 TaxID=1938855 RepID=A0A2A3JA66_9ACTN ---------RELEARHGARIGAFAYNLRTEATV-RHRAAERFPGCSVFKTLAAAAVLRDLD -QHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRHSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFHAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PARDAAADSPLVAATASVLA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI000BA63791 ------ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSAAVLHLAD -QGTLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGDVLTPASRL -QLADWLIDNETGDTRLRAGLSSAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDTLRQVAVIA---- ->[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. AX2bis TaxID=2653157 RepID=A0A653VTI5_9ACTN ---AVRGRLAALEEERDARLGVYAVDTGTGRSV-AYRGGERFAYASTIKALAAGAVLDDLS ---RPELRERVRWTEEDLVEYSPVTELHVEDGLTVRQLIDAAITVSDNTAGNLLFDLVGGP -GALDAALDDVGDRTTEVVRREPDLNTAVPGDPRDTTTPRALATSLGRYVLGDVLPAADRR -LLEATMRRTETGDALIRAGVPQGWRVGDKTGSAGYGTRNDVAVVRPPGGDPVLVAVMTTH -DEADAATDDALVADATRVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium RIFCSPHIGHO2_01_FULL_64_960 TaxID=1797553 RepID=A0A1F4EMP0_9BURK ---EWNETLASIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVQ-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR -STVRPEQRDAAIAQVARAVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000576B0B7 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWSPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas campaniensis TaxID=213554 RepID=A0A3D0KJP4_9GAMM ---NLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACASLLQRVD -EGSEQLERQVKVSASDIVTYSPVTEAYADNRISLFELCEATMTTSDNTAANLILQAIGGP -QAVTAFVRELGDSVTRLDRWETELNEAAPHDERDTSTPNAMVSNLEKLVVGNALSLQSKN -QLREWLVNNEVADGLFRSQMPDEWVIGDRTGAGGFGSRSITAVIWPPERKPTIVAFYITE -TDASFEERNSAIAELGSVI---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI000B89BDE5 ------ADFAALEKASGGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKFALSAAVLHLAD -QGTLPLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPDMNRFAPDDPRDTTSPAAMAASLQRFVLGEVLTPASRL -QLADWLIDNETGDTRLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLASYLQG -ATVDDAGRNDALRQVAVI----- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_030 TaxID=2175649 RepID=A0A2W0CH86_9MICO ---ATRRAFDGLEGAHDARLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAS ---PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP -SVVQQWLRGIGDQVTQVVRIEPDLNEATPGDDRDTTTPAQFAADLRTVLLGDALQPDDRE -LLVDTMAGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR -STADAEPDDALVAAATRTAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis flavescens TaxID=758803 RepID=A0A1M6JHB5_9ACTN ----LDSDFTRLEEEFDTRLGVYALDTGTGLAI-EFQADERFAYCSTFKVLAFGAVLDRTP ---LDQLDRVVTYSEADLVFHSPVTREHVSTGMTLREIGDAALRHSDNTASNLLFEELGGP -QGLGEALRGIGDDVTRVDRIAPEMAEAVPGDVRDTSTPRAMAASLRAFALGDVLPQEKRD -ILVAMMRANTTGDDLIRAGVPEGWRVGDKTGACGYGTRHDIGVLWPPAGDPVVLAVMSSR -DEAGAGYDDALVAQAAALAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas venusta TaxID=44935 RepID=A0A3Q8WG13_9GAMM ---TLLTEVERIEEQLDARVGFAAYDLETGQRW-EYNADQLFAMSSTFKTLACAALLQRVD -EGSEQLERRVKVSASDIVTYSPVTEAYADNRISLFELCEATLTTSDNTAANLILQAIGGP -QAVTEFVRALGDSVTRLDRWETELNEAAPHDERDTSTPNAMVSNLEKLVVGNALSPQSKN -QLRVWLVNNEVADGLFRSQIPDEWVIGDRTGAGGFGSRSITAVIWPPEREPTIVAFYITE -TDASFEERNSAIAELGSVI---- ->[subseq from] Class A beta-lactamase n=1 Tax=Ideonella dechloratans TaxID=36863 RepID=A0A643FHS3_IDEDE ---ALQQALQDIESRAGGRLGLAVLDTGSGRRW-LHRADERFLLCSTFKLLLCAQVLDRAA -RGEERLDRQLAFRRSDLVEWSPVTKKAVGRGLSVAQLCEATMTTSDNTAALLLLKTQGGP -AGLTRWLRAHGDTQTRLDRSEPDLNLADPTGEWDTTTPAAMADTVQRLCLGAGLPKTVQA -QLQAWMKASTTGAQRLRAGLPTGWQIGDKTGTGD-GISNDVAIVWPPGQAPWVVVAFLSN -CRSPREAQQACLAEVGRLL---- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010222E2C ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM1743 TaxID=318996 RepID=UPI000423204A -------ELETYERESGGRIGVYAENLTTGAKL-AWRADERFVMCSTFKASLAACVLGRVD -RGEEQLAAMIPYSQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLTRIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWMVNCKTGAKRLRGGLPAGWKIGDKTGYNGKDAAGDIAVAWPKPDTPVLITAYVQG -GTPTPAQIAAVFARIGHMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. MY 5-36 TaxID=1678027 RepID=UPI0007C7860C ---AADAAFAELEQRFGARLGVYAVDTGSGREV-VHRTDERFAFASTIKSLAAGALLRKAS ---DADLDKVVPYRQEDVLAWAPITSQHVATGMKLRDLAAAAIQYSDNTAANLVFAELGGP -AAVQQSLRDLGDSTTSVDRTEPTLNEATPGDTRDTSTPRVLAADLHRYVLGDVLPEGRRG -LLTDWLVGNTTGGPYIRAGVPADWRIGDKTGNAGYGTRNDVAVAWPSGGAPIVIVVLTDR -GKADATSDDALIAQATKTVVS-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2T1IMW5_STEMA ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -SAISNEQRAGVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium arachidis TaxID=858423 RepID=A0A1I7FFP1_9BRAD -----PSELESYERESGGRIGLYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD -RGDEQLAAMIPYGQADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARVGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLIVGEALSPASRA -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGRDASGDIAVVWPKNKAPILITAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium TaxID=374 RepID=UPI0003F5ADCB -----PSELESYERESGGRIGLYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD -RGDEQLAAMIPYGQADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARVGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLIVGEALSPASRA -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGNNGRDASGDIAVVWPKNKAPILITAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0003A4484D -----DREFRRLEMRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQYVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNEATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDNALIAQATEVVIA-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0009A112B6 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HGR7_9GAMM -----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD -RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP -AALTAFLRGLGDTVTRSDRLEPEMNGFVAGDPRDTTSPRAMATSLGRCVAGAVLAPASRL -QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG -SRVDSAARDAVLARAGQLAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. 1M-11 TaxID=1529006 RepID=UPI0006C76E53 ---EAENKLAELERKHPGRFCVTILDLGNGRRI-QHRADERILMCSTFKALLAAFALARVD -KGEEKLDERIKITKKDLVTNSPVTKPHLGGPLTIAELCDAIVTRSDNTAANLLLARFGGP -AALTAFCRRLGDDLTRLDRFELELNHDGPDDQRDTTTAAAMAETLRKLLFSDVLSAASRS -QLAAWLITNKTGDTRLRAGVPGDWLVGDKTGTNGHGNANDIAVIWPPDRAPLIVTAFCEI -PEISSKDRDAVIAEIGRIAS--- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI00101E7A60 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CNPSo 3448 TaxID=2560055 RepID=A0A4Y9LWM1_9BRAD -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGQEQLAAMIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNRSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGEDASGDIAVAWTTPDTPILIAAYTQG -GSPTAPQIEAAFARIGRMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mixta intestinalis TaxID=1615494 RepID=UPI001367748A ---ALTQQLAALEKSVGGRLGVAWID-EGASHY-GYRADERFPMTSTFKTLAVAAILHQNV -SQPHLLEKKIAIEEADRVPWTPVTGNYFGKKMSVAALCAAAIEYSDNLAANYLLKEAGGP -QGITRYARYLGDSVTQLNRLEPELNSAVPGDKRDTTTPAAMAENLYKLTLGTALPTAQRQ -QLISWLQQSTTGAESIRAGVPAGWRVGDKTGAGAYGSTNDIAILWPEKGAPKILAIYFTQ -PQPDAANNKAVLAAATRLTIK-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI000527D617 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Izhakiella capsodis TaxID=1367852 RepID=A0A1I4VBV7_9ENTR ---NLHLQLATLEKRYNGRLGMTLLDTASGHKL-QYRGNERFPMCSTSKTLLAAVVLNLSL -QQPGLLERRIYWDTSERLSWMPVTEKHYESGMTVNELCQAMLQYSDNLAANLMLKLVNGP -AAVTTLARSLGDNVTRLDRTEPALNSAIPGDKRDTTTPLAMASDLQKLAFGNGLPHREQQ -LWIRWLKGNTTGKQSIAAGVPAVWKVGDKTGSGDYGTTNDVALLWPPQRQPLVLTVYFTQ -PDKTAASNRTVLAETARLTLATw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB33_STEMA -----ATDFAALEKACGGRLGVSLLDVASGRRA-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFAVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAMAVTLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRAMVLAQVGRIA---- ->[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0S1ULF5_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 13MFTsu3.1M2 TaxID=1502776 RepID=UPI0008EB7A10 ----AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETLDRVVSYGAGDLLSYAPVTRKALGTGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMQATLGRVLLGTVLSPASRA -RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=[Kitasatospora] papulosa TaxID=1464011 RepID=UPI0004BE3BB8 -------AFQGLEKRFGARLGVYAIDTGTGASV-THRPDERFAYASTCKALLAGTVLGMHT ---LQQLERRVRYGPGDLVANSPVSERHVEAGMTLRALCDAAVRHSDNTAANLLFREIGGP -RRLQDALLALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALATDLRAYALGDVLGDEKRA -VLTDWLRRNTTGDALIRGGTPAGWPVGDKTGTGGYGTRNDIAVVWPPHSAPITIAVLSRR -ATRGAKPQDALIARAARVAL--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB51_STEMA ----AASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA -GAISYDQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000491E178 -----DREFRRLEQRFDARLGIYAIDTGTGRTV-RYQADERFAYASTYKALAAAEVLDETT ---DAELEQVVRYPADDLVDYSPVTEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDEVTDAARYETALNEATPGDRRDTSTARALTEDLRQYAVDDALEPADRD -ILNAWLRGNTTGGALIRAGVPDGWAVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DERGASYDDALIAQATEVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MA5143a TaxID=2083010 RepID=A0A2P9FCX1_9ACTN -----TDGLRALEGQYGARLGVYAHHVRTGKTI-RHRADTLFPICSLFKTLAAAAVLRDLD -RDGEVLSRRIHYTAADLLENSDVTREHLATGMTIAELCDATIRHSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSGEPWRITDTTSPRAIGRTYARLVLGDALSRPDRA -LLTHWLLHNQTSGTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSIMSRK -FDQDATTENKLIADTAHLL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NBS 14/10 TaxID=1945643 RepID=A0A229H1A4_9ACTN -----TREFRDLERKFDARLGVYAIDTGTGEEV-AYHDGERFAYNSTFKAMAAGAALKKYS ---LSGMDRKITYSKDVLIANSPVTEKHVATGMTLGELCDAAVRYSDNAAANLILKELGGP -KALDATLEKLGDDVTRMERPEPYLSEWVPGELRDTTTPRAFAKDLRAFVLGDVLAEGERA -QLTKWLRTNMTGDKVIRAGVPKGWVVGDKTGTGSYGGRNDIAVVWPPDSAPIVIAILSHR -GKKDAEPDDRLIAEAASVIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium cytisi TaxID=515489 RepID=A0A5S4W7X6_9BRAD -------ELESYERESGGRIGVYAENLATGAKL-TWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKTDLLEYAPVAKQNLPAGMSAADMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTISRLDHNEPELNRSPPGDPHDTTTPAAMAGNLKRLVTGEALSPASRA -QLTDWMVGCKTGANRLRGGLPAAWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAAYTQG -GTPNVAQIEAVFARIGRMVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Xylophilus sp. KACC 21265 TaxID=2697032 RepID=UPI00136779B4 --------LAELESAYGGRLGLALTS--AGRPLlSYRADERFPACSTFKALLAATVLNRAS -SDPGLLGRRVMYGQADLKTYAPVTGRLVDQGMTISHLCAAAVQYSDNVAANLLMREIGGP -AGVTAFARWLRDDSFRLDRWEPELNSAIPGDPRDTCTPRDMARNLHKLVLGQALPARERE -LLKSWLLGNTTGNGRIRASVPENWPVGDKTGTGEYGSTNDIAVIWPADGPPLVLAIYFTQ -FQADAQAREEVIVEATRLAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Competibacteraceae bacterium TaxID=2053538 RepID=A0A3C1STS0_9GAMM ---EAEKELVNLERACRGRLGVHVIDTSTGQRF-GHRSDERFLMLSSFKLLAAGFVLDRHD -RGEDSLDRRIRYTRADLVEWSPVTEKHVGGDLTLAELCHATITTSDNTAANLMHQSYGGP -AALTRFVRRLGDLTTRHDRYEPDLNTSDPNQPSDTTTPRAIAETTGKLVVGDVLSSSSRR -LLQDWLLANTTGGKRLRAGFPLGWRIGEKTGTAPSVGANDVGVAWPPDGAPLLVSAYVET -TSVSQETRDATIATVAKLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Dactylopiibacterium carminicum TaxID=857335 RepID=A0A272ESU5_9RHOO ---DLRALCKRLEQSSGGRLGVYMHDVCRSQEF-LYREDERFAMCSTFKWLLAAAVLGRVD -AGQERLDRRVRFSRRDLLEYSPATTPFADGPMSLAQLCEGAIVDSDNTAANLLLNALGGP -SGFNAFLRMQGDQVTRLDRPEPELNEARAGDPRDTSTPSAMGRDLHRLLLEDRLSAASCR -QLTDWMLATRTSGARLRAGLEEGWRLADKTGSGRNGTANDVGIYWTPAGDPIVLCVFLTG -ARFDGAAQAATIATLGRAV---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces klenkii TaxID=1420899 RepID=A0A3B0AQR1_9ACTN ---RIARRLRELEQEHSARLGVFAHNTATGRTV-AHRADELFPMCSTFKTIAVAAVLRDLD -RDGEFLAERIHYTKKEVEDYDKITGRNVANGMTVEELCAAAISYSDNGAANLLLRELGGP -TAVTRFCRSTGDRITRLDRWEPALNSAEPDRTTDTTTPRAIGRTYARLVLGNVLDPADRK -RLTGWLLANTTSGEKLRKGVPAGWTVADKTGAGSYGTSNDVGVTWTPHGAPVVMSILTTK -HEAGAEGDSPLVAETARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. K1PN6 TaxID=2596892 RepID=A0A5N8X3W8_9ACTN ------GELKELEREYDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS ---LSGMNRVVRYSEDDLIANSPITEKHVETGMTLSELCDAAVRYSDNAAANLLYEELGGP -KALEAELRKLGDKVTSMDRIEPHLSNWVPGETRDTTTPRAVAKDLRAYVLGDVLGKRERD -RLTTWLKTNTTGDEVIRAGVPEGWVVGDKTGSGSYGARNDIAVVWPPDSAPIVMAILTNR -GKEDDTHDNKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012962ED6 --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAINLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMEILRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHANNNDIAVAWSPNRGAIVVATYCEI -STISADERNAVVAEVGRLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. 7504-2 TaxID=2022547 RepID=A0A268IAG9_9BACI ---STTKQFKQLEEEFAARLGVYVIDTETNKTI-NYRADERFAYTSTFKPFAAAFILQKST ---ISELKKLKTFTTNDLVTYSPITEKHVQTGMNLLEISEAAIQYSDNTAGNLLLEELGGP -KGLQQALRKIGDQTTSVDRYETELNEATPGDSRDTSTPKALAKNLQYVGIDEFLSQSKKD -IFQDWLKGNTTGDSLIRAGVPKDWVVGDKSGAGGYGTRNDIAIVWPPERKPIIMVIMSSK -DEVEATYNDELIANTAKVIVETf ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. yr668 TaxID=1761801 RepID=A0A1I6VT36_9RHIZ ----AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETLDRVVSYGAGDLLSYAPVTRKALEAGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPDSRA -RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAHAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia lijiangensis TaxID=299618 RepID=UPI00082B3D2B -----HEHLAELERRFDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVSYTEADLLKSASVTSRHVATGMTIRDLCDAAVRFSDGTAGNLLLHDLGGP -AELTAYTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRALGTDYQQIVLGDALPADKRA -FLRDLLERNNTGAQRIRAGVPQGWTVADKTGTGDYGTLNDIGIVWPPGSAPLVIALMSSK -ATVDAPYDQALLAQAAAYIVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidobacterium sp. S8 TaxID=1641854 RepID=UPI00131E6928 ---SLPESLAKLEKDCEGRLGVAVLDIGSGESS-GYRVDERFAMCSTFKMLLAAAVLQRVD -TGKENLDRMVQMPTTGFLFNSPMTQPHAGGKMAVSDLCVAILTRSDNTGANLLLETIGGP -AGITQFARSLGDNVTRLDRVETALNEALPGDPRDTTSPAAMAANWRKVLLGDKLLTASRK -QLTDWLIANKTGDERLRAGSPTGWTVGDKTGSNGENTTNDVAILWPTAQAPVIVAAYLTS -CAGPESKRDAVLAEVGRQVAK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces misionensis TaxID=67331 RepID=A0A1H4NJ12_9ACTN --------LGVLERDYGARLGVYARNVRTGRVL-AHRAGERFAHCSVFKAFAAAAVLRDRS --GCAPLDKVIHYPPHDILPNSPRTEENQETGMTVADLCAAAIQYSDNTAGNLLLQQVGGP -AGLTGFFRSLGDRVSRQDRWEPELNTAIPGDLRDTTTPEAIATSLERLTLGRALPAPDRE -RLVTWMKGNTTSGARFRAGLPEGWTLADKTGTGFYASAHDIGVAWTTRRTPVVLAVLSTK -DEKDAPVDEALIREAARIAAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter sp. JB02H27 TaxID=2597703 RepID=UPI00124631C7 ----VVAALDRMAEELDARVGFSAYDLETGQRW-EYQADQRFPLLSTFKTLACAELLYRAD -EGEVPLSREVSFSDPDLLTYSPVTEKFAGRQMTLSELCEATLATSDNTAANLILRALGGP -ESITTFATSLGDDVTRLDRWETELNEAQPGDPRDTTTPNAMVSNIQRLLLGEVLSVASRR -QLRNWLEGNQVADGLFRAAVPEGWVVADRTGAGGFGSRSITAVMWPPERQPIVVALYITE -TESSLSERNEAIAKIGAVIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_005 TaxID=1898734 RepID=UPI0009F4D6B1 ---ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGERFAFASTIKVFIAAAVLGASS ---DTDLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGNAIDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR -ADPGAEPSDALVAAATRAAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus ehlersii TaxID=290111 RepID=A0A2D0IR12_9GAMM ----IIHQLSILEKNANGRLGVVLIDISDHSTI-TYRANERFPLCSTSKLMAVSAILKKSE -TNIHLLNQPVHYQRSDLVEYSPITEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGP -NEVTHFARTIGDNSFRLDRYEPELNTAIPGDERDTSTPQAMAKSLYNLVLGDALATIQRE -QLAEWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPVNRAPLVLVTYFTQ -PDKKASARPDVLAAAARIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax radicis TaxID=758826 RepID=UPI0004980336 ---QWNDTLAGIEHFAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDGITRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPPSRA -WLQRWLVDTSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR -STAKPEQRDAAIAQVARAVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus siralis TaxID=77777 RepID=UPI0010F571C5 ---STTEQFKQLEEEFAARLGVYVIDTETNKTI-NYRADERFAYTSTFKPFAAAFILQKST ---ISELKKLKTFTTNDLVTYSPITEKHVQTGMNLLEISEAAIQYSDNTAGNLLLEELGGP -KGLQQALRKIGDQTTSVDRYETELNEATPGDSRDTSTPKALAKNLQYVGIDEFLSQSKKD -IFQDWLKGNTTGDSLIRAGVPKDWVVGDKSGAGGYGTRNDIAIVWPPERKPIIMVIMSSK -DEVEATYNDELIANTAKVIVETf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCC3C -----EAQLAALESKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGDEKLDRRIHYKRGDLIDYSPATEPNAGDNMTVGELCAAAVTLSDNTAANLLLASFGGP -KAVTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFSDVLTPASRS -QLAAWLITNKTGDARLRAGIPKNWLVGDKTGTNGAGNANDIAVLWPASRAPIIVTAYCEI -PEIAADERNAIIAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium huanghuaihaiense TaxID=990078 RepID=A0A562S3H2_9BRAD -------ELETYERDSGGRIGLYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYSQADLLDYAPVAKHNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVTGEALSAASRA -QLTDWMVNCKTGANRLRGGLPADWTIGDKTGNNGKDASGDIAVVWPKNKAPILIAAYTQG -GTPNAAQIAAVFARIGRMVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P1ZF61_STRVZ ---ELVARLRELEARHDARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD -HDGTFLARRIRYTAADVKRWSPRTERNLARGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFVRSTGDRTTRLDRWEPELNSAEPWRESDTSTPRAIGRTYGRLLLGDALPHCDRE -RLTRWMLANTTSVERFRKGLPADWLLADKTGGGRYGTNNDAGVTWPPGGGPIVLAVMTTR -SLEDAPVVDPLVAEAAALVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KM273126 TaxID=2545247 RepID=A0A4R1DCW8_9ACTN ------GELKELEREYDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS ---LSGMNRVVRYSEDDLIANSPITEKHVETGMTLSELCDAAVRYSDNAAANLLYEELGGP -KALEAELRKLGDKVTSMDRIEPHLSNWVPGETRDTTTPRAVAEDLRAYVLGDVLGKRERD -RLTTWLKTNTTGDEVIRAGVPEGWVVGDKTGSGSYGARNDIAVVWPPDSAPIVMAILTNR -GKEDDTHDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. FXJ1.172 TaxID=710705 RepID=A0A176KZA6_9ACTN ----AAGELSALERRHGARLGVFARNLRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG --GCAPLDKVIHFPPHDILSNSPRTAEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFFRSLGDEVSRLDRWETDLGSAIPGDLRDTTTPEALGRSFERLTLGRALSGADRA -RLVGWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTANDTAVAWTTRGTPLLLTVLSAK -SAQDAAADDALVAEAARILAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Gracilibacillus TaxID=74385 RepID=UPI0008271176 ----SEEAYKELEDERDAKLGIYAVDTGTNQTV-AYRADERFAYASTFKVLAAGAILQNTS ---IDDLEKGITYSEEDLVTYSPVTENHVDDGMKLKEVMEAAIRYSDNTAGNLLLKELGGP -DGLEENLREIGDETIEVDRVEPDLNEAVPGDTKDTSTPKAFAESLQKYVLSDLLPEEKRK -LLIDWMTGNEAGDTLIRAGVPEGWKVIDKSGAGGYGTRNDIAVVWPSDHAPIVISIFSSR -DKEEADFDDTVVEKAAELVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus jeddahense TaxID=1462527 RepID=UPI000595FFDB ---QSEEAFKELEEEFDARLGVYAIDTETDQTV-SYRSDERFAYASTFKVLAAGAILQIAS ---MDDLEKVITYSEDDLVTYSPVTEEHVDDGMKLKEIMEAAIRYSDNTAGNLLLEELGGP -DGLEEILRENGDEIIEMDRMETDLNEAAPGDTRDTSTPKALAESLQTYVLSDLLPEDKQD -LLIDWITGNEAGDTLIRAGVPEDWEVGDKSGAGGYGTRNDIAVVWPSDQEPIIISVLSSR -DSEDADYDDALIEKAAERVME-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PRh5 TaxID=1158056 RepID=A0A014LIH0_9ACTN ---AVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK ---LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDATLEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. RFCAC02 TaxID=2499143 RepID=UPI0010218636 ---DAGRAFTDLEAEYGARLGVYALDTGTGREI-THRAGERFAYASTFKALAAGAVLRAYG ---THGIDRVITYTRDDLLAHAPVTEDFVHTGMSLRDLCAAALRYSDNTAANLLFDALGGP -DGLEAVLRGLGDGVTEVDRVEPDLNEAAPGDTRDTSTPRALAGSLRAFLLGDALAPDERG -LLRHWMTTNTTGGTLIAAGVPDGWTVADKSGSAGYGGRNDIAVVWPDDGAPLVIAVLSGR -DTEDAEPDDALIAGAAALAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0F6QEY8_KLEPN ----LEKRLAELEGRHKGRIGVAIHNLATGARI-GHRADERFLMCSTFKALLAAHILARVD -RKEETLDRRIVVGKSDLVDWSPVVETRVGGEISIAELCEAAITLSDNAAANLLLSASGGP -KAVTQFLRGFGDDVTRLDRTEPTLNRETPDDERDTTTPAAMAETLRKLIIGDVLARGSKA -QLAAWLVMNKTGDTRLRAGFPVDWTTGDKTGTNGHGNANDVAIAWSPDRGAVVVTAFCEI -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia sp. PT13C1 TaxID=2135612 RepID=A0A4R7RVV3_9RHOB ----LAKAAKAIESRLNTRIGVAVFDSASGLNW-NYNGEDRFPMNSTMKAFACAALLDRVD -KKQSSLDQRTIVTSDMIVSYSPVTEKHINTAMTLADHCEATITISDNTSANIILEELGGP -IGVTTFMRSIGDDVTRLDRYEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK -HLMEWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAIYVTE -NEVEFQARNKAIAEIGAAFK--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. SD340 TaxID=1690268 RepID=A0A0N8VUH6_9BURK ---EWNETLANIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMASTLKAVLAGWMLALVD -QGKERLDARVHYAAGDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDSITRLDRTEPTLNEAKVGDPRDTTTPQAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPTGGAPVLVTCYLTR -STAKPEQRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rhizosphaericus TaxID=114699 RepID=UPI000A3D2E3E ---AVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK ---LSGLDRVIRYSKDDLVENSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDATLEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangdongense TaxID=1325090 RepID=A0A410VFC9_9BRAD -------ELDSYERESGGKIGVYAENLTTAKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDKLAAMISYDKGDLLEYAPVAKQNLTTGMSVAEMCKAIVELSDNTCANLLLARVGGP -AALTKFWRSIGDTTTRLDHNEPELNRSPPGNPHDTTTPAAMAGNLKRLVIGEVLSPASRA -QLTAWMVDCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKPDTPILIAVYTQG -GTPSPAQLEAVFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-3229 TaxID=1463836 RepID=UPI0004BE5954 ---DVAARLRALEQRYDARLGVFAHRLSTGRSV-RFRADELFPMCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELAEVAITHSDNTAGNLLLRELGGP -TAITRFARSLGDRTTRLDRWEPELNTAEPWRLTDTTSPYAIGRTYGRLVLGDALDRRDRR -LLTHWLLSNTTSVDRFHAGLPASWTIADKTGSGSYGTANDVGVVWTEKGDPIVLSVLSTM -PEPDAVRDDALVADAAAVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. CNT312 TaxID=1137268 RepID=UPI00049164E3 ------AEFARLEEDFDARLGVYALDTATGRTV-EYRPDDRFAHCSTFKVLAFGAVLKRTP ---VAELDRVVTFDRSDLVFHSPVAQGHVSTGMTLRELGDAALRYSDNTASNLLLEELGGP -DALNGALREIGDETTRVDRFAPEMAQALPGDTRDTSTPRAMATSLHAFALGDVLSEAGRT -VLVDMMRANTTGDGLIRAGVPENWEVGDKSGACGYGTRHDLGLVWPPGGEPVVLAVMSGR -DEAGAAYDDALVAQAAAQAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia yamanashiensis TaxID=209247 RepID=UPI000834C97E ----ATTAFADLESKHAARLGVFAIDTGNGRTV-GYREGERFPMASTFKGLACGALLDKHP -LSSGYFDQVIHYPATDLVDYSPETEKHVDTGMTVAELCKAAITLSDNTAGNQLLKLLDGP -AGLTAYLRTLGDATSRLDRWETELNTAIPGDERDTTAPGVLAADYRALTVGTELPEAERA -QLKSWLVASTTGGNRIRAGLPAGWTVGNKTGSPAYGSALDVAVAWPPNRAPIVIAVLTTK -SEQQAEPDNALVAAAARTAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI0013254621 ---AVQRELRRLEASYKGRIGAYAVDTGTGRVV-SHRADERFGFASTFKSMAAAAVLRKAR -TDPGLMDRRLHWTRADVLDYSPITEKHVEDGLTVAEVCAAAVEYSDNTAGNLLLEQIGGP -AGLTRYLRSLKDPVSRLDHFEPELNPWKPGQKHDTTTPAAVGRDLSEVTLGRSVPAPDRA -RLIGWLKGNTTGDKRIRAGLPKGWTVGDKTGTGGYGTANDIAVAWPPSGAPIVLAIYTNR -RAADGEADDAVVARTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus licheniformis TaxID=1402 RepID=UPI00023EAC13 -----KDDFAKLEEQFDAKLGIFALDTGTNRTV-AYRPDERFAFASTIKALTVGVLLQQKS ---IEDLNQRITYTRDDLVNYNPITEKHVDTGMTLKELADASLRYSDNAAQNLILKQIGGP -ESLKKELRKIGDEVTNPERFEPELNEVNPGETQDTSTARALVTSLRAFALEDKLPSEKRE -LLIDFMKRNTTGDALIRAGVPDGFEVADKTGAASYGTRNDIAIIFPPKGDPVVLAVLSSR -DKKDAKYDDKLIAEATKVVMK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium sp. NFR17 TaxID=1566260 RepID=A0A329AE82_9RHIZ -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP -GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTNVLTPASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI -PAIAADERNAIIGEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI00077E0157 --------------------------------------EERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QFIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 285MFTsu5.1 TaxID=1172187 RepID=UPI00037A3498 ----AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETLDRVVSYGAGDLLSYAPVTRKALGTGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA -RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID3212 TaxID=2690259 RepID=UPI00136E13AA ----LTRQLLALEEERSARLGVFAHDVATGRTV-LHRGHERFPICSVFKTLAVAAVLRDLD -RDGEYLSRRVRYTERDVVRHAPVTGANLAQGMTVEALCAASITHSDNTAANLLLGKLGGP -ASVTRFCRSVGDTVTRLDRWEPELNSAEPDRVTDTTGPYAVGRTYARLILGHALDPGDRE -RLTGWLLANTTGGARLRAGLPDDWTVAEKTGTGDYGTTNDVGVAWPPGRRPVVLSVLSTQ -EDPDAPADDQLVARTAALVT--- ->[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga sp. NML030171 TaxID=2008676 RepID=A0A208XW35_9BURK ---AALDELARLERLIDGRLGVCIVDTASGEEL-GRRADERFQMLSTFKLLAAGFVLARHD -RGEDSLDRRIRYTRQDLVNWSPVTGKHVGDRMTLAELCHATMTTSDNTAANLILRSFGGP -EALTRFIRGLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGRLTVGEALSPASRE -RLQAWLVGNTTGDKRLRAGIPAGWRIGEKTGTYSKVGANDIGLAWPPARPAILMSVYVAS -TRVSDEVKDQVIAKVAELA---- ->[subseq from] Beta-lactamase n=3 Tax=Bacillus TaxID=1386 RepID=A0A0V8JHY4_9BACI ---TIERKLAKLENKYDAKLGVYALDTGTNKTI-AYRPNERFAYTSTHKALAVGVLLQKNS ---IKDLDKRITYTRDDLVNYNPVTEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP -IGFKKALRELGDNVTNPVRMEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE -LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR -NEKDASYDDKLIAEATKEVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Shinella sp. WSJ-2 TaxID=2303749 RepID=A0A372NGW3_9RHIZ -----QEQLAELEARHKGRIGVAIHNLATNARL-SHRADERFLMCSTFKALLAGHILARVD -RKEEALDRRIVVKKSDLVEWAPVVEKRVGGKITIAELCEATITLSDNAAANLLLGASGGP -KAVTAFLRGFGDKVTRLDRSEPALNYEAPDDERDTTTPVAMTETLRKLLFTDVLSPRSKA -QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAVAWSPNRGAIVVTAFVEM -PGISGDERNALIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0007DC0F96 ---TIERKLAKLENKYDAKLGVYALDTGTNKTI-AYRPNERFAYTSTHKALAVGVLLQKNS ---IKDLDKRITYTRDDLVNYNPVTEKYVDAGMTLKELSDASLRYSDNTAGNLILEEIGGP -IGFKKALRELGDNVTNPVRMEPELNDVPPGEIADTSTAKALATSLQAFTLGDALPVEKRE -LLIDWMKRNTTGDALIRSGVPKNWEVADKTGAGLYGTRNDIAVIWPKKGDPIVLAVLSSR -NEKDASYDDKLIAEATKEVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora rosaria TaxID=47874 RepID=A0A136PUH3_9ACTN -------RFAALEARFGARLGVYAVDTGSGRTV-AHRPDERFAYASTFKALAVAAVLEATT ---DAQYDRLVRYRRADLVAHSPVTGRHVAEGMTLRAVADAALRYSDNTAGNLLLAELGGP -RGFERALRGIGDTVTTPARVETALNQATPGDVRDTSTPRALATSLRTYAVDDHLDAGDRA -VLVDLLRRNTTGDALIRAGVPAGWQVGDKTGSGGYGTRNDIAVLWPPDGAPIVLAVLSRR -DTVDAPHDDALIAEAARVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Kiloniella majae TaxID=1938558 RepID=UPI000A2786FA -----VETVTGLEESIGGRIGVAVYDLQTGQKW-EYRSDEKFPMSSTFKPFACAALLTQNE -RKDETLERMVSVSRDDLVSYSPVIEKYADDGVSLRKSCEATVSISDNTAGNLVLKEIGGP -EGFTRFMRSIGDNTTRLDRWETELNEAQPDDLRDTTSPKAIATSLQKLLLEDALSPEARI -EITNWMLNDRVADDLFRSRLPKGWKIADKTGAGGFGSRGIIAVIWPPSHKAVVASVYMTG -NDADFKTRNAAIAEIGAAIFE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-146 TaxID=1463884 RepID=UPI000D144155 -----TARLRELEQEHTARLGVYGRNLRTGRTV-VYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRVHYTQEYVTKYSPITKDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAVTRFARSVGDRVTRLDRWEPELNSAEPWRVTDTTTPRAIGLTYARLVLGTALEPRDRA -RLTDWLLRNTTSTEKFRKALPADWLIADKTGGGRYGGNNDVGITWPPDGPPIVMSVLTTQ -PEEDAP----------------- ->[subseq from] Beta-lactamase n=1 Tax=Marinisporobacter balticus TaxID=2018667 RepID=A0A4R2K910_9CLOT ---QYNSAFSQLESDYDVKLGVYAFDTETNKEV-VYRADDRFAYCSTFKVLAAGAVLKQDS ---LAQLKQTVKYDKKDVLSYAPIAKNNVDKGMTIEEICEAAIRYSDNTAANLLLDHIGGP -NGFKSVLNQLGDKITQPARIEPELNEGIPGDIRDTSTPRQLVTDLQAYITGNILTEDKKK -ILIGWMTGNATGNTLIRAGAPNNWVVADKSGTGPYGRRNDIAIVMPPNKKPIIIAILSTH -DTKEAKHDDKLIAQASKIVFDSf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Z26 TaxID=2500177 RepID=A0A498E5H0_9ACTN ---RAREEFDRLEGAYDARLGVYAVDTATGREL-TYRADDRFAFASTFKALLTGTGLQRDS ---VKDLEKRLTYDRDDLVPNSPITEKHVDTGISVRGAMDAAVRYSDNTAANLLFREYGGP -DAFEAALRRIGDRTTRSDRIETALNETTPGDPRDTSTPRAMADSLRAFTVGKALPVEKRK -ILTTMLRENTTGGPLIRAGAPEGWVVGDKTGAADYGTRNDIAVIWPPGRAPVMLAVLSDK -DTKDAEYDDALVADAAKAALAVf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SA15 TaxID=934019 RepID=A0A2A2Z3Q8_9ACTN -----TAELKELEREFDARLGVYAIDTGTGQEV-AYRDGERFGYHSTFKAMAAAAVLRTYS ---LSGMNEVIRYSVDDLVRNSPITEKHVDTGMTLRQLCDAAVRYSDNTAANLLFEALGGP -KGLEAELRKLGDDVTVMERIETGLSDWVPGETRDSTTPRAFAEDLRAYVLGDVLRKPERA -QLTKWLKTNKTGDELIRAGVPEGWVVGDKTGSGGYGGRNDIAVVWRPDAAPVVMAIMSNR -SEKDDTYDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus jostii TaxID=132919 RepID=A0A1H5MG08_9NOCA ---SLDAKIDELEARYSTRIGVTAVDPTTGVTY-SHRGDERFAMCSTFKAYASAAVLRATE -DGSASLDKAIVIEPADLVENSPVTAAAAGTPMSLGQIAEAALTQSDNTAGNYLLREIGGP -AAITALARDLGDESTRLDRWETELNTAFRGDPRDTTTPNGLTQGVRALLLGDALDTASRE -QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWTPDGDPIVLTILTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM2254 TaxID=1188263 RepID=UPI000400FDE0 -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGQEQLAATIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNRSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWMVGCKTSANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWTKPDTPILIAAYTQG -GSPTAPQIEAAFARIGRMVA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154M3F5_9PSEU -----RADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP ---IAELDQTVTYSRQDVVTGSPVTEKHAGTGMSLRAVMDATLRYSDNTGGNLLFRELGGP -AGLTSVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDVLPEDKRK -ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLAVLTDR -STKDAKIDNALLARATAATVK-- ->[subseq from] Beta-lactamase n=1 Tax=Mixta sp. BIT-26 TaxID=2562439 RepID=A0A506VED7_9GAMM ---ALTQQLAALEKSAGGRLGVAWID-AGASHY-GYRADERFPMTSTFKTLAVAAILHQNV -SQPHLLEKKIAIEEADRVPWTPVTGSYFGKKMSVAALCAAAIEYSDNLAANYLLKEVGGP -QGITRYARYLGDSVTQLNRQEPELNSAVPGDKRDTTTPAAMAENLYKLTLGTALPTAQRQ -QLISWLQQSATGAESIRAGVPAGWRVGDKTGAGAYGSTNDIAILWPIKGAPKILAIYFTQ -PQPDAANNKAVLAAATRLAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Allosalinactinospora lopnorensis TaxID=1352348 RepID=UPI000623C7A5 -----AAEFERLEEEFDARLGVYALDTGTGLDV-AHRSDERFAYASTFKPLACGAVMERRS ---IAELEEVVGYGAEDLVEYSPITEEHVDTGMTLLEACDAAIRYSDNTAANLLFDELGGP -QGLQDALVEIGDDTTQADRRETGLNEAAPGDTRDTSTPEALAADLREYVLGDPLPEEKRT -LLREMLLENTTGGDLIRAGIPDGWEVGDKTGSAGYGTRNDIAVLWPPDGDPIVLAVLSSR -DGEDAESEDALIAEAAAVAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7KTM6_9BACT --------FGSIERQVAGRLGVAVLDTATGRRL-AYRADERFAMCSTFKWLLGAQILSRAD -AGTEHLSRVVSYGETDLLEYAPVTRAHVREGMTISGLVSAAIQYSDNTAANLLLQTVGGP -ASFTAYIRQLGDRVTRLDRVEPDLNSAIPGDARDTTTPNAMVANLRVVLLGDHLGRAARD -QLIAWLVGNTTGAEKLRAGLPATWRVGDKTGMGAHGATNDVAITWPINRGPVLVAAYLVD -TEAGVAGRNDALANVGHAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces abyssomicinicus TaxID=574929 RepID=UPI0012509461 ------TRLRELEERHGARVGVHARNMATGTTV-RHRADERFPILSVFKTLAAAAVLRDRD -TDGGFLDRRIRYTKAQLVENSDICEANLATGMTIRELCAAAIQWSDNTAGNLLLREIGGP -HGITRFARSLGDPVTRLDRWETELNSGEPWRETDTTSPAAIAATYARLVLGGALERPDRE -LLTSWLLGNRTGKTRLRAGLPPEWTIADKTGAADYGSLNDVGVVWTEDGTPLVMAVLTTK -PERDAPRSDILLEDVARVLVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. MK-45 TaxID=2496836 RepID=A0A3S9MMM5_9ACTN ---DVSARLRALEEQHGARLGVFAHNLATKRTV-CHRADERFPICSLFKTLAAAAVLRDLD -RDGEVLNKRIHYTAADLVENSKQTEAHLATGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETDLNSAEPWLVTDTTSPRAIGRTYARLVLGNALNRPDRD -LLTHWLLNNTTSVNRFRAGLPKTWTIADKTGGGFYGANNDAGIAWTEDGTPLVLVVQTTQ -PEQDAAPDHALIVETAELLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces pharetrae CZA14 TaxID=1144883 RepID=A0A1Y2Q1U5_9ACTN -----TGRLRALEREYGAKLGVYAHNVGTGHTI-RHHADDLFPICSVFKTLAAAAVLRDLD -RDGEFLARRIHYTEADLVDGSDETGKHLAEGMTVAELCDVTIRYSDNAAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE -LLTHWLLNNTTSLDRLRAGVPPTWTVADKTGGGDYGVNNNVGIAWTPDGTPVVLAVLSRT -SDPAAVRENALIAKTAKVLTE-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A3R8UJS5_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A1Q4JJD9_9PSEU -----RADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP ---IAELDQTVTYSRQDVVTGSPVTEKHAGTGMSLRAVMDATLRYSDNTGGNLLFRELGGP -AGLTSVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDVLPEDKRK -ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLAVLTDR -STKDAKIDNALLARATAATVK-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1S2B316_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI00050A19A1 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. IF17 TaxID=1830119 RepID=UPI0011814E76 --eALERAFAGLEERYDARLGVYAVDTGTGEEI-VHRADERFAYASTFKALAAGAVLLEYG ---TGGIDEVIPYGEEDLVEHSPVTGEHAGVGMTLRELCDAAVRHSDNTAGNLLFDALDGP -EGLNDTLREWGDGVTVMSRYETELNEAVPGDERDTSTPRALATNLRALLLEDLLEEAERD -LLTEWMLTNVTGSELIAAGVPEDWTVADKSGAGGYGTRNNIAVVWPPEGDPMVLAVLSAR -DVEGAEWDNALIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. S4.7 TaxID=2705439 RepID=A0A6C0PXA1_9ACTN ----TKAAFARLERRIDARLGVYAIDTGNGRSI-THRPDERFAYASTCKALLAAVMLDRYS ---LRQLDRLVRYDRNDLAGYSPITEKHIATGLTLRELCDATVRYSDNGAANLLFRELGGP -KSLQSALASIGDRVTRCDRYEDALSAAVPGDLRDTSTPRALATDLRAYVVDDALAPDKRA -VLTDWLKRNTTGDKVIRAGAPDGWQVGDKTGTGGYGTRNDIAVVWPPKAAPIAIAVLSRR -DFKDAEPDDALIAEAAGITL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TM32 TaxID=1652669 RepID=A0A4Q1RVZ3_9ACTN --dELSRRLTDLEQQHSARLGVFAHNTATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTQKDVRDYAPVTGTNLARGMTVADLCAAAISASDNAAGNLLLRELGGP -AAITRFCRSIGDRTTRLDRCEPDLNSAEPWRITDTTSPRAIGQTYTRLTLGTALTPEDRK -RLTGWMRATTTGGEKFRAGLPSDWTVADKTAGGKYGTNHDAGLTWPPGRSPIVMAVLTTK -REPDAAADNPLIAETAALLAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. Cp5.3 TaxID=443598 RepID=UPI0004122098 -------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLSAMIPYSQADLLEYAPVARQNLAAGMSVADMCKAIVELSDNTCANLLLARVGGP -AALTAFWRTIGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGESLSPASRG -QLTDWMVNCKTGANRLRGGLPGTWKIGDKTGNNGKDASGDLALVWPSPDKPLVIAAYTQG -GTPSPAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764) TaxID=1179773 RepID=K0K2Z6_SACES --------WAGLERKFDARLGVYAVATGSGATF-AYRADERFAFCSTFKGLAAAAVLQRNP ---LAHLDTVVTYTDADLMKSSTITREHVATGMTIRDLCDAAVRYSDGTAGNLLVRDLGGP -AGLTAFLRGIGDGVTRADRTEPALTEAAPGDPRDTTSPRAIGTDYQRIVLGDVLPADKRA -FLRDLLERNTTGARRIRAGVPLGWVVADKTGTGEYGTVNDIGLGWQPNAAPLVIAVMSSK -TTTDAKYDEALIAEAAAQVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI95-17 TaxID=1522759 RepID=A0A3N6G6L1_9ACTN ---RFARQFEDLERKYDARLGVYAIDTGTGREV-THNDAEHFAHASTFKALAAGAVLHKYS ---LGGMDEVIKYSKKDLVSDSPVSERHVGTGMSLSALCDAAVRFSDNTAANLLLDRLGGP -RGLDAVLADIGDDVTRMEHREPELNRWSPGATSDTSTPRALAGDLRAFVLGDLLGNGERA -QLTKWLRTNTTGAELIRAGMPRGWVVGDKTGSGGYGTRNDIAVVWRPDGAPVVVAILSNR -FQEDAEYDNALIAEAASVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces coeruleorubidus TaxID=116188 RepID=A0A5J6IDG1_STRC4 ------ALLRELEREHTARLGVYARNLRTGRAV-AYRADERFPMASVFKTLAAAAVLRDLD -RDGEFLARRIRYTQDYVTKFSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP -TAITRFARSIGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPRDRA -RLTDWLLRNTTSTEKFRKGLPADWLLADKTGGGRHGGANDVGITWPPDGPPIVLSVLTTQ -PEEDAAADNPLVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio coralliilyticus TaxID=190893 RepID=UPI000810A177 --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDHFPMMSTFKTLMCANALYLAE -QKKLNLNATTTVKESDLVTWSPITEKLTGQEIAVQKACEATMLMSDNTAANIVLHQIGGP -EQVTQFVRSLDDSVTRLDRFEPELNQATPGDKRDTTSPSAMVKLLNTLLLQDGLNQESQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPVILSIYLTQ -TQLDMAQRNRVINQVANLVFEQf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB865C -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATKPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP -GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTDVLTPASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI -PAIAADERNAIIGEIGRIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0SYK5_STEMA ----AASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPSLLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. 58S1 TaxID=1404864 RepID=A0A516J292_9BRAD -------ELESYERDSGGRIGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD -RGEEHLAAMIPYGKADLLDYAPVAKQNLATGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTTFWRSLGDATSRLDHNEPELNRSPPGNPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWMVGCKTGANRLRGGLPANWTIGDKTGNNGKDASGDIAVVWPNTSTPILIAAYTQG -GAPNAAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KE1 TaxID=1638939 RepID=A0A0H1ACS5_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TEQDATRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. JUb134 TaxID=2485112 RepID=A0A4R2YDT6_9SPHN ------DPLAAIASEAGGRLGVSVLDTGTGRRL-WLDPLARYPLCSTFKVPLAAAILARAD -RGELDLQRPIRFTQGDLLDYAPVVRENLPRGMTLAELCAAAVEWSDNAAANLLLPQLGGP -SGLTRFLRSAGDTITRLDRVEPELNDYKPGELRDTTTPMAMTTLLAALLTGDVLEPASRK -QLTDWMIGCRTGDKRLRAGLPKSWRVGDKTGTSGNGQANDIAIAWPPSRKPILIACYLDA -PGIAPEKADQAIASVGSLVGQL- ->[subseq from] Beta-lactamase n=1 Tax=Salinisphaera sp. TaxID=1914330 RepID=A0A2E0IYA6_9GAMM -----IAAIRDLEARYGGRMGVAVHDAALGRAV-AHRGDERFLMCSTVKLPAAAMILSRVD -AGRESLDRHIDYAAADLVTYSPATERRVASGMTLGAICRAGLTLSDNTAANLMLASVGGP -AALTVFLHSLGDNVTRSDRYETALNEHAPDRLHDTTSPRAMLGLMQRVLLGDVLSAPSQR -QLVTWMRANETGDHRLRAGLPDAWRIGDKTGSGGDNTANDIAIIHPGVGAPLLVTAYYAG -SNATKTQRDRVLADVGRAV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium miluonense TaxID=411945 RepID=A0A1C3UE17_9RHIZ -----EAQLAALESKHPGRICVSILDMGSGKRI-EHRAGERILMCSTFKALVAALVLSRVD -KGEEKLDRRIHYTKSDLLGNSPATEANVGETMTVAELCAAAVTLSDNAAANLLLASFGGP -KELTAFCRSLGDEITHLDRIEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSPASRS -QLAAWLIMTKTGDARLRAGLPKNWLVGDKTGTSDVGNANDIAVLWPSNRAPIIVTAYCEI -PGIAADERNAVIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia altamirensis TaxID=472158 RepID=UPI0014355804 --------FTDMEAKYGARLGVFAVDTGTGRTV-TQRDGERFPIASTFKGLACGALLRDHP -LSTGYFDQVIRFPATDIVANSPITETRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP -EGFTAFLRSIGDQTSRLDRWETDLNTAIPGDDRDTTTPAALAADYRALVVDDVLAKPERD -QLTTWLVANTTGATRIRAGLPADWRVGDKTGTPAYGCALDVAVTWPPGRAPLVIAALSAK -DQEHAEPANALIADATKAVVT-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI00101E781A ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSVTASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A1W2B1E8_KIBAR -----HDQLFDLERRFDARLGVYAIATGSGATI-VHRSDERFAFCSTFKGLAAAAVLHRNP ---MAHLDTVLTYTEADLMKSSAITKRNVATGMKIRDLCDAAVRFSDGTAGNLLLRDIGGP -AQLTAYLRGLGDDVTRMDRIEPTITEAKPGDPRDTTTPRAIGTDYQRIVLGDALAADKRD -FLRDLLERSVTGAKRMRAGVPQGWRVADKTGTGDYGTLNDIGVVWPPDAPPLVIAIMSSK -SAADAKYDEAVIAEAAAYVVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 6176 TaxID=1470557 RepID=UPI00055D39E6 ---------RALEERYSARLGVHARNTRTGQSV-GYRAGERFALCSTFKVFAAGAVLRDHA --GSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP -AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPEALGASLERLTVGDELSGAARE -QLLTWLKGNTTSDRRFRAGLPRGWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSK -DAPDATVDEALIADAAAVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter salarius TaxID=1420917 RepID=W5YPJ8_9ALTE ---------KTVEQRLDARVGIALYDSGTGESW-DYHGDDRFPITSTFKTLACAALLAKVD -NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIDGP -DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGEALSKGSRD -TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVIAIYITQ -TDASFDERNGAIRDLGGAIVKHf ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium sp. RAC02 TaxID=1842534 RepID=A0A1B3MEG8_9RHIZ ---ALEKRLAELEARHDGRLGVAILNLATGARL-GHRTDERFLMCSTFKALLAGHILARVD -REEEALDRRIVVKKSDLVDWAPVVEKRVGGDISIAELCEATITLSDNAAANLLLAASGGP -KAVTEFLRGFGDDITRLDRTEPALNYETPDDERDTTTPVAMVETLRKLIFGDVLSPRSKA -QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAIGWSPNRGAIIVSAFVEM -PGISGDERNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1A6XSS0_STEMA -----ATDFAALESACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RALALLDRRVPVRGADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDVAVLWPLGGAPWVLTAYLQA -GAISNEQRARVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_055 TaxID=2175633 RepID=UPI000DAA14B3 ----TARAFAVLERRYDARLGVAAIDTGSGRTI-VHRAGERFAFASTIKVFIAAAVLDASS ---DADLATLVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRIADKTGTASYGVRNDIAVVTPPGRDPIVLVVMTSR -ADAGAEPSDALVAAATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rhizosphaericus TaxID=114699 RepID=UPI0013D90569 ---TVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK ---LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDAILEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. TaxID=409 RepID=A0A2E7YJA8_9RHIZ -------DWGTLERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAVAAVLARVD -TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP -EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG -RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSVNDIAILRPPGRAPVVVAVYVTG -STASAETYAAAYAEIGRLIA--- ->[subseq from] L2 family class A beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000DAABFAC -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATALSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5727 TaxID=1463871 RepID=UPI0004C512CC -----VARLRALEEQYDARLGVHAHDVCTGRTL-AHRDRERFPMCSVFKTLAAAAVLRDLD -HDGTFLARRLTYTADYVERWSPVTKDNIARGMTVAGLCDATIRFSDNTAANLLLRELGGP -TAVTRFARSLGDPVTRLDRWEPELNSAEPWRITDTTTPRAIARTYGRLVLGKALEPADRA -LLTDWLLRNTTSLHRFRKGLPADWTVADKTGGGEYGGNNDVGVTWPPDGGPILLSVLTTR -FEPDAEGVDELVAAAAAIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia altamirensis TaxID=472158 RepID=UPI000B003D12 --------FTDMEAKYGARLGVFAVDTGTGRTV-TQRDGERFPIASTFKGLACGALLRDHP -LSTGYFDQVIRFPATDIVANSPITETRVDTGMTVAELCHAAITVSDNTAGNQLLKLLGGP -EGFTAFLRSIGDQTSRLDRWETDLNTAIPGDDRDTTTPAALAADYRALVVDDVLAKPERD -QLTTWLVANTTGATRIRAGLPADWRVGDKTGTPAYGCALDVAVTWPPGRAPLVIAALSAK -DQEHAEPANALIADATKAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. V2 TaxID=1424099 RepID=A0A2V1NTU4_9ACTN ------DVFAGLEEEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLRE-- ---GLDPTKRIHYTQQELTDYAPVTEKHLDTGMTVGELCAAAVSHSDNAAANFLLRELGGP -TAITRFARSLGDPVTRLDRWEPDLNSAEPWRTTDTTTPHAIARTYAKFLLGDVLRPADRT -RLTSWMVANSTNVTRFRAGLPADWILADKTGGASYGVANDVGVVWPPGRAPLVIAVLTTT -YAAEGPSKNELVAKAAARVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium radiotolerans TaxID=31998 RepID=UPI0005E98AD3 -----EPDWTAIERRLGGRLGIAAAS-ADGVLA-AYRADARFPMCSTFKVLAVAAVLARVD -AGRETLGRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP -AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD -RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG -STASPDACAAAYAEIARLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenovibrio sp. Milos-T1 TaxID=90813 RepID=UPI00057118BE --eSFDQQVHELEQTYGGRLGVSIWDSDSNTSL-HYRGGERFAFCSTFKFLLVAAILKKVD -DKQLALDQQIPYGTSDLLSYAPITRKHLKSPMSISQLSAAALQYSDNTAANLLMKQVGGT -KGLTAFMQSIGDKTTRFDRIEPDLNSNLPNDERDTTTPDAMLKAMKQILLGSVLSHASRD -QLTQWLLNNTTGANKLRSGFPTFWPVGDKTGSGDNGATSDIAITWPDPDHPILVAVYYTD -SKQPFEIKNHVIELIGKIISEQf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. MKU004 TaxID=1849370 RepID=UPI0007E2E4C2 -------SFQDLEKQYDAKLGVYALDTGSGESV-SHNADERFAYVSTHKALAVGVLLKNKA ---IDELDERIKFTKEDLVDYSPVTEKHVDTGMTLRELSDASIRYSDNTAGNLILESIGGP -LGFKEVLREIGDDVTEPERTEPELNYVEPGETRDTSTPKALVKSLEAFTLEDILTEEKKN -LLNDWLKRNTTGDALIRAGVPEGWAVGDKTGAGSYGTRNDIAVIRPPDGDPIILAVLSSR -EERDAELDDELIAKAAELAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Rc3b TaxID=1855322 RepID=A0A1I4QF62_9BRAD -------ELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACMLARVD -RGEDQLAAMIAYGKPDLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPHDTTTPAAMAGNLQRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPGTPILIAVYTQG -GTPNPAQIEAAFARIGRMAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. EGI 650086 TaxID=1840409 RepID=UPI00131BA2E8 -----HDRLAELERKFDARLGVYALATGTGATV-AYRADERFAFCSTFKGLAAAAVLHRNP ---PAHLDAVVAYTEADLMKSSLITRQHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYTRSLGDTVTRMDRIEPLITEATPGDPRDTTSPRAIGADYQRIVLGDALPADHRA -FLRDLLERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAVVWPPKSAPLVIAVMSSK -AAKDAKYDQALLAEAAAYVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Arsenophonus endosymbiont of Nilaparvata lugens TaxID=1247023 RepID=UPI0005096617 ---ELANIVKQEEKKLNSRIGVAVIDTANKVTV-SYRGNERFPLNSTFKALLCGMLLNQVD -NGKIVLTESVQFEKGQLVAHSPVTEKFIAPLMNWKQLCAAAISYSDNTAANLIEKKVGGP -TSFTRFLRSIGDRVTRLDRFEPELNSAIPGDKRDTTTPVAISQTLQKLVLGDVLQPSSRQ -QLRQWMEDDKVANALLRSVLPAQWKIADKTGTGDHGSRSIISLVWPEKRQPLIVSVYITQ -TKATLAQSNEAIARIGKAIFS-- ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia sp. CCTCC M2018092 TaxID=2492396 RepID=A0A3G9BKU9_9ENTR --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -RGEFALSDTTQFSKETLMDYSPVTSKFVAPKMSWQQVCSAAIEYSDNTAANLVAQKLGGP -QKVTAWFADLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSHTLEKLTLGDALKPESRA -QLVQWMKDDKVADALLRASLPSGWEIGDKTGAGAYGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia vulneris TaxID=1141657 RepID=A0A0C1APL0_9NOCA -----TAELTALEQQYDAQLGLFAVDTGSGKTL-TNRADQRMPFLSTFKGLAAGALLQAHP -LATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP -QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERE -QLTKWLKTNTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVLAIQTRK -STKTAEPSNDLVAAATKLVVDK- ->[subseq from] Beta-lactamase n=1 Tax=Pseudosporangium ferrugineum TaxID=439699 RepID=A0A2T0RQE1_9ACTN -----NSGLSELEREYDARIGGFALDTGNGRTV-QHRATELFPLLSTFKVLASAAVLRRAR -TDPGLLDRVIHYDAADLVTYSPITSQHVEDGMTVAALCEAALTYSDNTAGNLLLRLLGGP -PAVTRYARGLGDPVTRLDRWETALNDWSPTELRDTTSAKAMGRNLQAVTLGQALHPEDRA -RLTGWLRMNTTGDARIRAGLPAGWVVGDKTGSSDYGAANDIAVVQPPSGAAIVLAIYTNR -NAPDATYDNTLVARTATALVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI0009736FCB --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLAAQKLGGP -QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA -QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAHGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium 66-474 TaxID=1895868 RepID=A0A1M3QIH7_9GAMM ----VAAQLAMLERKHGGRLGVAMLDTGSGKGA-GHRADERFLMCSTFKLLLAAAVLKRVD -EGRERLDRRIVFGKDVVLDWAPVTGKHVGRPMTVAELCEAAITLSDNTAANLLITRIGGP -GVVTGFARSLGDPHTVLDRMEPELN------PRDTTTPDSMLGDMQKLLLGDVLSQASRG -QLTHWLLNCQTGLHSLRAGVPDGWRVGDKTGQWDTGANNDIAIIWPPGRKPLLVAAYYMT -DTTDVAARKAVLAEVGRIAA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DA3F721 -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDSRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. S45 TaxID=1641861 RepID=UPI00131BCE60 -------ELVAIERACGGRMGVYVRDTGSGGRL-LHRADERFPMCSTFKALMVGQVLSQVD -HGQVSLDKRIAYGRTDLLPTSPVTSKHVAKGLPLRELCAAVIEYSDNGAANLILREIGGP -ASLTAWLRGQGDAITRLDRNELALNSAIPGDPRDTTSPLAMGATFERLTLGDILKPASRD -RLQAWLAANTTGADRLRAGLPGPWTLGDKTGSNGADTANDVALIRPPGRAPLIAAVFVTR -AT-SQEAANHAIASVGALI---- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus thuongxuanensis TaxID=1873484 RepID=A0A1Q5U7K3_9GAMM ---EITHRLSILEKNANGRLGVVLIDTADHSTI-SYRANERFPLCSTSKLMAVSAILKQSE -TNVHLLNQRVHYQQSNLVEYSPITEKYLNDGMTLRELSAATLQYSDNTAMNLLLNQLNSP -SEVTRFARTIGDNSFRLDRHEPELNTAIPGDKRDTSTPQAMAKSLYNLVLGNALATTQRE -QLTEWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPVNRAPLVLVTYFTQ -PDKEASARPDVLAAATSIVTN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ST1015 TaxID=1848900 RepID=UPI000DDA09F1 --------FAGLEEEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLRDGV -----DPAKRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP -TAITRFARSLGDPVTRLDRWEPDLNSAEPWRTTDTTTPHAIARTYAKFLLGDVLRPADRT -RLTSWMVANSTNVTRFRAGLPADWILADKTGGASYGVANDVGVVWPPGRAPLVIAVLTTT -YAAEGPSKNELVAKAAALVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=A0A317D7J8_9ACTN ---SADRQFGELERRFGARLGVYAIDTGTGRTV-THRADERFAHASTFKALLAAVLLRRLS ---DEDLRRVVTYTEADLLEHAPITSQHVATGMPVEDLIAAAVRYSDNTAANLLLNEIGGP -KGLQGELRKIEDRTTNINRNEPTLNEAVPGDDRDTSTPRALGTDLRTFALGDVLPKARRL -KLTDLLIGNTTGGPYIRAGVPSDWKVGDKTGSGGYGTRNDIAVVWPPTGSPLIIAIQSDR -GVPDASSADPLIAEATKVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TLI_146 TaxID=1938858 RepID=A0A2N3W7D4_9ACTN -------DFKELERKYGARLGVYAVNTGDGREV-GYRDGERFAYASTFKALAAGAVLRKYS ---LKGMTKVVKYSKDDLVTNSPVTEKHVDTGMTLGELGDAAVRYSDNTAGNLLFDALGGP -KGLESALRQTGDAVTRVERREPDLNQWAPGTLRDTSTPRALAQDLRAFVVGDRLGTAERA -QLTRWLRTNTTGDALIRAGVPKGWTVGDKTGAGGYGIRNDIAVVWPPGAAPIVMAILTNR -GTKDADFDNKLIADAAAVVAR-- ->[subseq from] Beta-lactamase class A n=2 Tax=Amycolatopsis saalfeldensis TaxID=394193 RepID=A0A1H8THS3_9PSEU ---SVQPELAALEKEFGGRLGVSAVDTGNGATA-GYRADERFLLCSTHKVLAVSALLHGHP ----DALDKVIHYDKAQLVTYSPVTSLHVADGMTGAAICEAAITVSDNTAANLIVGQVGGP -AAVTAFVRALGDPETRLDRLEPDLNVGAPGDERDTTTPARMAADLRALVLGSGLDPAGRE -RLTGWMVANTTGGKQVRAGVPAGWRVADKTGSGSHGESNDVAVVWPTGRAPWVIAVYTAP -SDPKSTAGPATIAEATRIVAKAf ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. 6K520 TaxID=2530364 RepID=A0A4R5EFJ0_9ACTN ---KVTEQIRRLEKARDMRIGAYILDMGTGRAL-GHRADETFPFASTFKAMACGAALQKAR -RDPGLMDRVIRYKESDLSPHSPVTEKHVKTGMTVADLCHATITKSDNTAGNLVLKQIGGP -AGLTAFFRSLGDRVSRSDRWEPALNDWRPGEKRDTTAPRVWAADLGSLTVGDALVPADRK -RLVGWLKATVTGDERIRAGLPDGWTAGDKTGTGGYGSANDIAVAWPPSGAPVVIAILTTK -RTPDADPDEQAIARTTTILIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mixta theicola TaxID=1458355 RepID=UPI00136342B6 ---ALTQQLAALEKSAGGRLGVAWID-AGASHY-GYRADERFPMTSTFKTLAVAAILHRNV -SQPHLLEKKIAIEEADRVPWTPVTGSYFGKKMSVAALCAAAIEYSDNLAANYLLKEVGGP -QGITRYARYLGDSVTQLNRQEPELNSAVPGDKRDTTTPAAMAENLYKLTLGTALPTAQRQ -QLISWLQQSATGAESIRAGVPAGWRVGDKTGAGAYGSTNDIAILWPIKGAPKILAIYFTQ -PQPDAANNKAVLAAATRLAIK-- ->[subseq from] Beta-lactamase class A n=3 Tax=Streptomyces TaxID=1883 RepID=A0A2N0GNX3_9ACTN ---RVAEALKRLEREHGARLGVYALDTGTGRAV-THRADELFPMCSLFKTLAAAAVLRDLD -HDGSVLARRIHYTLDDVERISEWTKRNLANGLTIGELCEVSITYSDNTAANLLLRELGGP -SAVTRFARSLGDRVTRLDRWEPELNSAEPERVTDTTTPRAIGRTYARLVLGDALARPDRE -LLTRWLCANTTSSERFRKGLPAGWRLGDKTGGGSHGTNNDVGIAWRPAGAPLVLAVLTTK -PAQDADADNALVARTAALLAEAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. DASNCL29 TaxID=2583819 RepID=UPI00110F8AE2 ---AVAGEFKKLERSYDAHLGVYAIDTGTGHEV-AYRDGERFAFASTFKALEAGAVLRKYK ---LSGLDRVIRYSKDDLVDNSPVTEKHVDTGMSLGALCDAAVRYSDNTAANLLFDQLGGP -KGLDAILEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMAKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGTYGARNDIAVVWRPGAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium luteum TaxID=33881 RepID=A0A175RVX1_9MICO ----ADSAFAALERGSDARLGVVAVDTESGTTL-AYRGGDRFPFASTNKVFIAAAVLDRSS ---AADLDTVVHYDRGDLLAYAPVTARHVDTGMTVLELVDAAVSMSDNTAANLLVERLGGP -DAVEAWLRGIGDRTTRVDRLEPELNAATPGDVRDTSTPEQFAADLRDVLLGDVLDADDRR -VLQRAMLATTTGDGTIRAGVPSGWRVADKTGTGEYGVRNDIGLVTPPGRRPIVLVVMTRT -DRPDAGPSDALVAEATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=A0A1Q9SUT8_9ACTN ------RRLSKLEAKRNLRIGAYAIDTGTGRFV-SHRAGQRFPYASTFKAMACGAVLQKAR -TDPGLMERVIHYTEDDLVDYSPETEKHVGTGMTVSALCHAAITQSDNTAGNLVMKQLGGP -AGLTRFFRSLGDDASRADRWETALNEWKPGERRDTTVPAAWAGNLRALTAGDALAPADRE -RLIAWMKANTTGDARIRAGLPDSWTIGDKTGTAGYGNANDIAVAWPEGDAPLIMVVLTTA -KKKDAEADDAAIAETAAILA--- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas fluorescens TaxID=294 RepID=A0A5E6RYY9_PSEFL ---QLGATATQIERRTGGHLGISVMDVASGAQW-SYRGDQRFPMASTFKAFTCASLLSQVD -QGRLDLSQRIAFTQDELDSYSPVTRDHVGGQLSLLQLCDAATSMSDNTATNLVLKTVGGP -AGLTAFMRSIGDNSTRIDRYEPELSDVPPGDPRDTTTPNAAAKSLQALLLGDVLSDASRQ -QLETWLVANKVSAALLRASLPEGWKIADRTGAAEYGSRGIIAVIWPETHGPVVVAAYLTG -TRLSLEERDTVLAEVGAALV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5193 TaxID=1463860 RepID=UPI00068A5169 ---AAAARFRALEERYGARLGVHAHDVRTGRTL-AHRDDERFPMCSTFKTLAVAAVLRDLD -HDGTFLARRLHYTAAYVARWSPVAGSNIARGMTVAELCDATIRFSDNTAANLLLRELGGP -TAITRFARSTGDPVTRLDRWEPRLNSAEPWRITDTTTPRAIARTYGRLVLGRVLEPADRA -LLTDWLLRNTTSLARFRKGLPADWTVADKTGGGEYGTNNDVGVTWPPDGGPILLSVLTTR -PEPEAGGVDELVAAAAAVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus sp. GBA129-24 TaxID=1612551 RepID=A0A1L7FAU1_9PSEU ------AELADLESRFGVRLGVYAHDTGSGTVV-AHRADERFPMCSTFKALLGAAILHESS ---TVELDRHFTWSEADLLYHSPITEGNVASGMSAEQLCDAAIRYSDNTAANLLLTEIGGP -AGFTAFVRTLGDDVTRLDRIEPDLSTGEPGDERDTTTPAAFAGDLRSLVLGDALASERRV -MLTDWLVGNTTGEGRIRAGTPEGWRLGNKTGSGGYGTVNDTAVLWPPDREPILLTVYTTM -GVRYAEYDEAVIAEASSIAL--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A5B2VFQ9_9BACT ---------------------------------------ERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATKDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Nocardia puris TaxID=208602 RepID=A0A366DBE2_9NOCA ---DLAAEFAALETEFDARLGVYAIDTATGREI-AHHADDRFAFASTHKALTAGALLERNT ---LAELERVVTYTEADLLEHAPITEQRVATGMTLLELIDAAVRYSDNTAANLTMAELGGP -QGFEDALRAIGDNVTESDRWEPDLSDYTPGDPRDTSTPRAMATSLRAYTLGDLLPPDRRA -TLVDLLVRNTTGDTTIRAGVPEDWIVGDKTGSANYGTRNDIALLWPQEGAPIVVAIMSNR -GQEDAARRDELVAGAARVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum SEMIA 5079 TaxID=476282 RepID=A0A023XSQ0_BRAJP -------ELESYERETGGRIGVYAENLATGAQL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMVGCETGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKNKVPILIATYTQG -GTPNAAQIEAAFARVGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. B183 TaxID=1526762 RepID=A0A086WLA7_9VIBR --dSLTKQIALIEQQSGGRLGVAVLDTQNHNQW-QYHGDDRFPMMSTFKTLMCANALYLAE -QKKLNLNATTKVKESDLVTWSPITEKLIGQEITVEKACEATMLMSDNTAANIVLHQIGGP -EQVTQFVRSLDDKVTRLDRFEPELNQATPGDKRDTTSPSTMVELLNTLLLQDGLNQEPQQ -QLLTWMKNNKVSDPLIRSVLPQSWSIADRSGAGNQGSRGITALVWNSQRKPIILSIYLTQ -TQLDMAQRNRVINRVANLVFEQf ->[subseq from] Beta-lactamase n=2 Tax=Saccharopolyspora erythraea TaxID=1836 RepID=A4F9H1_SACEN -------ALAELERRYDARLGLTAVNVRTGREL-KHRADERFAMCSTFKTYAAGALLAAHP -LAGGYFDKVIRYTRADLRPNSPVTETRVDTGMTVAELCEAAITRSDNAAGNLLLAELGGP -AAIAPFARSIGDPTTRLDRWEVELNTAIPGDERDTTTPAGIAAGYRAMVVGDALGAPERE -QLKKWLIANTTGGERIRAGLPPNWVTGDKTGSGDYGTANDVAVTWTESGDAIVIAILTSK -SAPDRKYDNRLHADTARIVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JF72_ECOLX -------------------------DTADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLXAAAKIV---- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium radiotolerans (strain ATCC 27329 / DSM 1819 / JCM 2831 / NBRC 15690 / NCIMB 10815 / 0-1) TaxID=426355 RepID=B1M0E1_METRJ -----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAAAAVLARVD -AGRETLGRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP -AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD -RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG -STASPDTCAAAYAEIARLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=UPI0009ECF7A6 -----RADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP ---IAELDQTVTYSRQDVVTGSPVTEKHAGTGMSLRAVMDATLRYSDNTGGNLLFRELGGP -AGLTSVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDVLPEDKRK -ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLAVLTDR -STKDAKIDNALLARATAATVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia concava TaxID=257281 RepID=UPI0009FD1E16 ------PAFRTLEQDHGARVGVFALDTGTGKSI-GYRQNERFTINSTFKSLACGALLRAHP -LNTGYFDQVVHFTADEIVSASPVTQTRVDSGMSVTELCEAAITRSDNTAGNQILKLLGGP -QAVTDFARSLGDQVTRLDRWEPDLNTDIPGDERDTTSPAALAADYRALVLGDVLATPERK -QLTDWLLANKTGDARIRAGIPADWKTGDKTGSGDYGTANDAAVTWPADGPPLVIVVLSSK -PDQAAPADNPLVAAAAKEAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI000463F7F3 ----TARAFGDLERKFDARLGVYAIDTGSGRTV-THRPDERFAYASTCKALLAGAVLDRNT ---LRQLDRLVRYGRDELVSNSPITERHLATGLTLRELCDAAVRYSDNAAANLLFRELGGP -RGLQDALRALGDDVTRCDRYEVALSDGVPGDLRDTSTPRALAADLRAYVLGTTLPADKRA -VLTDWLKRNTTGDHTIRAGTPDGWQVGDKTGSGGYGTRNDIAVIWPPGAAPIALAVLSRR -DTEGAERVDALIARATEVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces natalensis ATCC 27448 TaxID=1240678 RepID=A0A0D7CB98_9ACTN ---RTTARLRHLEHQHHAVIGAFAHNLATGAQV-RHRAHTRFPILSVFKTLAAAAVLRDLD -HHGETLSRRIRYTRRDLVDNSPITSQHLADGMTVADLCDAALRYSDNTAGNLLLRQLGGP -TAITRFCRSLGDPTTRLDRWETDLNSAEPWRRTDTTTPYAIAHCYGTLLTGRALDRRDRA -RLTDWLLHSTTSGERFRAGLPKDWTVADKTGSAGYGAANDVGIAWAPDGAPVVLAVLTRK -PGPSAPYDNPLIAETAKVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. UNC300MFChir4.1 TaxID=1502747 RepID=UPI0008C27119 ----AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETLDRVVSYGAGDLLSYAPVTRKALGTGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA -RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Ruegeria atlantica TaxID=81569 RepID=A0A0P1EB16_9RHOB ---PLTETVQSWERRLDARIGLLLYDPSKEWEV-SYRADELFPMSSTFKTLLCGAVLAEVD -AGTESLSDHVTYQSADLVDYSPVTSKHVETGMTVGALCEATVTISDNAAANLLLRRLDGP -AGLTEFLRTNGDDITRLDRWETALNEAAPGDPRDTTTPRAILATLDRLLFGQALSPASSA -QLRQWMIDDQVADGLIRAHVPDGWTIGDKTGAGGHGSRAIVAFLQTPEPRTYLAAIYLTE -SDAPFPERNAVLSDIGRAMIS-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus spitiensis TaxID=252394 RepID=UPI000A2ED613 -----EVAFDRVEREHDVRLGVYALDTGSGRVL-VHRADERFAYCSTIKALAAGAVLRVSS ---DERMDEVIPYRQADLVSHSPVTEDHVGTGLSLGALCEAAVRSSDNTAANLMLTELGGP -DGFQRVLRELGDEVTRSDRYETELNDAVPGDERDTSTPRALASTLRALLLGDALPGERRE -VLEDWMSNNATGDELVRAGVPSTWRVVDKSGGGYYGTRNDIAVAFRPDAPPIVLAVLTSR -TERDAEGRAEAVAAAARVVAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas bentonitica TaxID=1450134 RepID=UPI000C9C11DF -----AKDFAALEAASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGRLPLDQRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga kullae TaxID=151784 RepID=A0A4V2F2J8_9BURK ---AALDELARLERLIDGRLGVCIVDTASGEEL-GRRADERFQMLSTFKLLAAGFVLARHD -RGEDSLDRRIRYTRQDLVNWSPVTGKHVGDRMTLAELCHATMTTSDNTAANLILRSFGGP -EALTRFIRGLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGRLTVGEALSPASRE -RLQAWLVGNTTGDKRLRAGIPAGWRIGEKTGTYSKVGANDIGLAWPPARPAILMSVYVAS -TRVSDEVKDQVIAKVAELA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00106FB613 -----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMGGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI0008A41527 -----AKDFAALEAASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGRLPLDQRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM1253 TaxID=319003 RepID=I2QJM1_9BRAD -------ELEAYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSATSRA -QLTDWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GTPSAAQIEAVFARIGHIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDF1B24 -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAGLVLARVD -KGKEKLDRRIRYTESDLIGGSPATKAHVGDGMTVAELCAAAVTLSDNTAANLLLASFGGP -EAITAFCRSLGDETTRLDRIEPQLNYDTPEDLRDTTTAAAMLENLRRLLFADVLSAASRS -QLAAWLITTKTGDARLRAGVAKDWLVGDKTGTSDAGNANDIAVLWPANRAPIIVTAYCEI -PEIAAGERNAIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. CFHS0054 TaxID=2382165 RepID=A0A386ZHR3_9NOCA ------TAFRNLEQQHNARIGVVAIDTGTGKTL-GYRQQERFAFDSTFKALACGALLHAHP -LSTGFFDQVRHFGSDKVVANSPVTSTRVDSGMTVAELCEAAITVSDNTAGNQILELLGGP -AALTAFLRSIGDQTTRMDRWEPDLNTNIPGDDRDTTTPAAIAADYRALVLGDTLAAPERT -RLTDWLLATKTGDTRIRAGLPADWKTGDKTGSGDYGTANDIAVTWPAGGAPLVIAVLTTK -PEQAAPFDNPLVAAAAKATVD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1I6JXY3_STEMA -----AMDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR -RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRAHGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPAARQ -QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPMGGAPWVITAYLQA -ADISNDQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus sp. 7505 TaxID=2022548 RepID=A0A268HZE7_9BACI ------ASFSSLEETYDARLGVFAIDTGSGRTV-AYRENERFGFASTHKALSVGVLLQQKS ---MEDLNKRIMFTGDDLVNYNPITEKHVDSGMTLKELSEASISYSDNTAANLIFEEIGGP -EGFEEGLRKIGDQVTNSESIEPELNNTVPGETRDTSTPKAMAESLRAFALEDHLAADKRQ -LLIDWLKGNTTGDALIRAGVPEDWEVGDKTGAGSYGTRNDIAILWPPGEEPIVLAIMSDC -DEADAKADDDLIAQAAEAVVT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR4_STEMA ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -SAISNEQRAGVLAHVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BMR7_9PSEU ------AALVEVERKFDARLGMFALNTATGVTV-THRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTIVRYGKGDLLKSAVITSQHVTTGMTIRDLCDAAIRYSDGTAGNLLLRELGGP -QQLTEYLRGLGDSVTRMDRTEPAIVEATPGDPRDTASPRALGTDYQKIVLGDVLPEDKRA -FLRDLLERNTTGAQRIRAGLPPDWRVADKTGTGDYGTINDIAVVWPPGAAPLVIAVMSSK -AAKDAKYDQALIAQAASHA---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCCE4A -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARVD -RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAADERNGIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Root241 TaxID=1736501 RepID=A0A0Q8XDM1_9SPHN ---EFRRAVAAVEQASGGRLGLAIIDTGSGERF-GRRGAERFPMCSTFKFALAGLILKQVE -RKRETLARPIPVAAADIVANSPFCEARVGGSASIAELCHATITVSDNSAANLLLRTIGGP -SGFTRWLRSVGDPATRLDRWETEMGEARPRDVRDTTTPVAMAGLARRLLLGNALAPAGRA -QLTGWMKDTRTSRNSLRAGLPAGWTVADKTGAGGYGTDNLVAMVWPPRRAPLVVASYITG -STLEFEKRRPLHAGIGRAIVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. p1417 TaxID=2681492 RepID=UPI0012F6683B -----AQAFKQLERKFDARLGVYAVDTGTGREV-AYNDGRRFAYNSTFKALAAGAVLRKNT ---LAGMDRVVKYSKDDLLANSPVTEKHVDTGMSLRALCDAAVRYSDNTAANLLFDELGGP -KGLDAALERLGDHVTRVERIEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDVLAEPQRA -LLTRWLKTNTTGDHVIRAGVPKNWVVGDKTGTGTYGARNDIAVVWRPDAAPLVVAILSHR -ADKDAAPDDRLIAESASVVAD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A649UHN4_ACIBA -----------------------------------WRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLAPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] Beta-lactamase n=1 Tax=Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) TaxID=479433 RepID=C7Q6I7_CATAD ------AAFAQIAAHYQAQLGVYAVDTGSGRTV-GYQADQRFAFCSTIKALAAAELLHRDT ---DAQLAQTIHYSASDLVDYSPVTSQHVNDGMTLTAVMTAAIEVSDNTALNLMLDRLGGP -AGLQTALRGMNDATTDADRPEPAVNSAVPGDVRDTSTPRAMAEDLRAYVLGNALSPQRRA -LLTSWLTANTTGGPYIRAAVPAGWTVGDKTGNGDYGTRNDIAVLWPPHRAPIVIAVLSHR -DGKDATSADALIADATKVALQ-- ->[subseq from] Beta-lactamase n=2 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VBQ8_9MICO ---DTTEDFEELEQRYQARVGVYAIDTATGSEV-GWRDDERFAYASTIKALAAAALLDQVG ---VSGLAKAISIDAADIVTYSPVTETRVGGNMTLGEIAEAALTVSDNTAANYLFEELGGP -DALGSALTEIGDDTTVVSRIEPELNEAVPGDDRDTSTPQALATSLEAYVLGDALPEAEAT -QLESWMTATQTGDDLVRADLPTDWTVGDKSGSGGYGTRNDIAIVWPTEGAPIVIAVMSSR -DDEDAESDDRLIAEAASTAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MOE7 TaxID=1961713 RepID=UPI0009FFEE5E ----AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD -HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGNTYARLALGNALDKADRT -RLTGWLLANTTGGKRLRAGLPDGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR -PAPDAEADDAVIAETAALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM2793 TaxID=1038866 RepID=UPI0003810058 -------ELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACMLARVD -RGEDQLAAMIAYGKPDLLDYAPVAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGNPHDTTTPSAMAGNLQRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPGTPILIAVYTQG -GTPNPTQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces iranensis TaxID=576784 RepID=A0A060ZSY1_9ACTN -------RMRELEREYGARLGVFALDTGTGRAV-VHRADERFPICSVSKTLAVGAVLRDLD -RDGEYLARRIRYTEDDVKTHIPITGTNIANGLTVEELCAAAISYSDNGAMNLLLRQLGGP -TAVTRFCRSLGDGITRLDRWEPDLNSAEPGRVTDTTTPRAIGRTYAGLAVGRALEAGDRK -RLAGWLVANTTGDARIRAGVPGGWTVGDKTGTGRYGTTNDVGIAWPPDRAPIALAVLSTR -PEQDAEAVDPLIAKATALAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Jeotgalibacillus sp. R-1-5s-1 TaxID=2555897 RepID=A0A4Y8KVK9_9BACL ---TMNSSFEDLEKEYDTKLGVYALDTGNNQSV-AYNEDERFGYASAHKALAVGALLKKKS ---MEELDERINFTEEDLVNYNPVTEEFVDEGMTLKELSDASIRYSDNTAANLIFEAIGGP -EGFKEVLREIGDDVTEPARIEPDLNDVEPGETNDTSTPKALAESLQAFTLGDVLSEEKRE -MLNDWLIRNTTGDNLIRAGVPEEWIVGDKTGSGSYGTRNDIAVIWPPDEEPIILSILSSR -EEPDAEYDDELIAKAAEIAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Lysobacter antibioticus TaxID=84531 RepID=UPI0003466829 ----WNAQLTRLERDSGGRLGVAALDTGDGKRL-GWRGGERFPMCSTFKFLLAAAVLREVD -RGRLDLQRKLPIAKSDIIAHSPTTEPLVGVGASVATLCEATMTLSDNAAANLLLPLIGGP -AGLTRFLRSIGDPVTRLDRIEPELNVVGPGDERDTTSPDAMLDSLRTLVLGDALKPASRE -RLTAWLVANKTGDKRLRAGLPAGLRVGDKTGTANT-TANDLAAIWPAPRKPVLLTCYLTG -AGIDAAGRDQVHAEVARTLAQIw ->[subseq from] class A beta-lactamase n=1 Tax=Crossiella equi TaxID=130796 RepID=UPI000A3B4CD2 ----ADEAFLALERKFGARLGVSVVDTGSGRTL-AYRADERFAHASTFKALAAGVVLRRAS ---DADLDRVIQYTEKDLLEYAPITKQRVGTGMSLRELLDASVRYSDNTAANLIFTYLGGP -QALQRELRALGDVTIQVDRVEPALNEATPGDPRDTTTPAALATTLRALALGDALTPPRRQ -VLVELLQGNTTGGPYVRAGVPAGWRVGDKTGSGGYGTRNDVAVVWPDGGAPLVLALLSDR -GKPGAESGDALLAEATRAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. ABOLF TaxID=1985879 RepID=A0A430DP98_9SPHN ------DPLAAIASEAGGRLGVSVLDTGTGRRL-WLDPLARYPLCSTFKVPLAAAILARGD -RGELDLQRPIRFTQGDLLDYAPVVRENLPRGMTLAELCAAAVEWSDNAAANLLLPQLGGP -SGLTRFLRSAGDTITRLDRVEPELNDYKPGELRDTTTPMAMTTLLAALLTGDVLEPASRK -QLTDWMIGCRTGDKRLRAGLPKSWRVGDKTGTSGNGQANDIAIAWPPNRKPILIACYLDA -PGIAPEKADQAIASVGALVGQL- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N7EMQ1_9ACTN -------RFATLECKHDARLGVYALATGTGATV-AYRADERFAFCSTFKAFAAAAVLHRNP ---LQHLAERVTYTEADVNSISPITKNHVRSGMTIRQLCDAAVRYSDGTAGNLLMRDLGGP -AELTAYLRRLGDTVSRMDDYEPQLNRVPPHDPRDTTTPRAIATNYRKLLLGDALSADKRA -LLTGWLNHNTTGAKRIRAGVPKGWTVADKTGTGDYGRAVDVGVVWPPDTGPLVVAVMSDR -RGYDTPPVDVLISEATARVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CDB55A ----TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAAKQA -VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKIALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces luridiscabiei TaxID=164114 RepID=UPI0006E35B8E ----TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAAKQA -VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKIALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. B1 TaxID=91459 RepID=UPI0005B8F27D -----EPDWGALERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAAAAVLARVD -TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP -EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG -RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSINDIAILRPPGRAPVVVAVYVTG -STASPETYAAAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bobili TaxID=67280 RepID=UPI000A369531 ------ARLRALEEAHGARLGVFAYNVRTRRSV-RHRAAERFPVCSLFKVLAVAAVLRDLD -RNGEVLARRIHFTADDLVENSPETELHVADGMTVAELCDAAIRRSDNTAANLLLRELGGP -AAVTRFARSIGDRFTRLDRWEPELNSAEPWRVTDTTTPYAIGRSYARLVLGDELAAHDRR -RLTDWMLANRTSDNRFRAGLPPAWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQVTM -PEREAAYDHALIVETTKLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=B5GLA6_STRCL ------ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP ---IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP -SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA -LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR -PGFRTPPSERLIAEAAERIV--- ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. AC402 TaxID=1282361 RepID=V4Q7H7_9CAUL -----AAAMLEITQRHGGRIGVSAVDTDSGARL-SVSSQDRFAMMSVFKWILAAAVLARVD -AGELKLDQVVRYGAKDLIAWSPVTEKKVKDGIAVGELCAATVSKSDNTAANLLLPLVGGP -DGLTKWIRSLGDEVTRCDRKEPELNANTDGDLRDTTTPQAMTQLLQIVFTGVALEPESIK -QMRAWMVATTTGDKRIRAGVPSGWTVANKTGTAN-GAVNDVAVIWPKTEGPIFLSIFTTG -GALEADAKEQVVADIARLVCEVf ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. XJLW TaxID=739141 RepID=A0A2U9TSF7_9RHIZ -----EPDWGALERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAAAAVLARVD -TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP -EALTAWLRDTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG -RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSINDIAILRPPGRAPVVVAVYVTG -STASPETYAAAYAEIGRLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0U5I5E2_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RVPALLDTRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A1D7VNM5_9ACTN ----VVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPMCSTSKAMAIGAVLRDLD -HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMSVADLCGAAVSYSDNTAMNLLLTELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGRTYARLALGNARDTADRT -RLTGWLVANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIVWPPGRGPIVMAVLSTR -PEPDAEMDDAVIAETAALL---- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBA1_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRTTIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -RAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Actinophytocola xanthii TaxID=1912961 RepID=A0A1Q8CVN4_9PSEU ------ARLRELEAGFGGRIGVAARR--GGRTL-HYRAGERFAMLSTAKALVVAAVLHRAP -CDPGLLDLVVRYGADDLVEHSPVTERHVDAGMTVEALCDAAIRQSDNTAANLLLRQLGGP -DDLTRFARFIGDRVTRLDRWETELNSNLPGDPRDTTTPAAMAADLEALVLGDVLAAEDRE -RLTGWLVGNTTGDARVRAGLP-GWRVGDKTGTGAYGAANDIGVAWPPSGPPLVLAVFTTR -PEEAAEPADEVVAEIARVVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Micromonospora globbae TaxID=1894969 RepID=A0A420ETS4_9ACTN -------GLVALERRFDARLGVYALDTGTAATI-AHRADERFAFCSTFKGLATAAVLHRHP ---LSYLETVVRYTRRDLMESSAITRRHVDTGMTLRQVCDAAVRYSDGTAGNLLLRELGGP -AALTAYVRSLGDTVTRMDRIEPTIVEATPGDPRDTTSPRAIGTTYRAILLGDALADDRRA -FLRDLMERNATGAARIRAGVPRGWTVADKTGTGDYGTLNDIGVVWPPGAAPLVIAIMSSR -AERDAAYDQALIAEAAAYVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_043 TaxID=2175627 RepID=UPI000D8CF107 ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -NAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDELVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Pigmentiphaga sp. H8 TaxID=2488560 RepID=A0A3G8GUY6_9BURK ---AALDELARLERLADGRLGVCIVDTASGEEI-GRRADERFQMLSTFKLLAAGFVLARHD -RGEDSLDRRIRYSRQDLVNGSPVTGKHVGDRMTLAELCHATVTTSDNTAANLILRSFGGP -EALTRFIRSLGDGVTRCDRYEPELNVPHATGMLDTTTPHAITRTLGKLAVGEALSPASRE -RLQAWLVGNTTGDKRLRAGIPASWRIGEKTGTYAKVGANDIGLAWPPGRPAILMSVYVAS -TRVSDEVKDQVIAKVAELA---- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013C340CD ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKP---------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium 23 TaxID=2035215 RepID=A0A2G6TTH8_9BURK --qAFRTELARIEKSVGGRLGVAVLEVESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=UPI00099C181B ----TAAGLRALEREYGARLGVYALDTASGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD -HDGSHLAKRIHYTLQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNAAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTGPRAIGRTYARLALGDALDPGDRE -LLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPIVLAILSTM -PEATAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS227 TaxID=1982763 RepID=A0A209C6Y0_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TEEDATRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=3 Tax=Delftia TaxID=80865 RepID=A0A1D8IUJ0_9BURK --qAFRTELARIEKSVGGRLGVAVLEVESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=F1CGM0_SHISO -----LEQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia endophytica TaxID=401976 RepID=UPI00104392B3 ------AELAGIESRFGGRLGLYALDTGTGRAV-GHRADERFLMCSTTKVPLIALVLRRSV -EDTGLLDRRIRWTRDDLLEYAPVTTPNLATGMTVAELCAAAVTVSDNTAANLLFAQVGGP -QAVTAFVRGLGDPLSRFDRVEPALNDTAPGDGRDTTTPARFAETLRLLTLGDALPPPQRD -RLVGWMDAATTGAAQIRAGVPAGWRVGDKTGSGNRGESNDVGVVSAPGRAPIVVTVFTAP -SDPDSTAGKPTIAAATRAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Paracoccus sp. PAMC 22219 TaxID=1569209 RepID=UPI000698EB1F ---TIEQAARAVEADLGGRVGVALRRHDDPTTH-GYRMDERFPLSSTFKVPLCGAILTLVD -AGEDQLDRVIGYVPGDLVSHSPVTEAHVADGMSVAQLCHATITQSDNTAANLLLDRVGGP -RDLTEYLRAIGDDTTRLDRWETDLNEGTPGDPRDTSTPAQMIDTLDALVLGPVLSDPSRR -QLEAWMQADAVADDLIRASLPNGWQIGDKTGAGGHGSRSIIAVIRPPQGGVWLASVYLTE -NDADMATRNRAIARIGAAMVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiales bacterium RIFCSPLOWO2_02_FULL_67_64 TaxID=1797564 RepID=A0A1F4J7Y2_9BURK ---AVQDSLRQIEATARGRLGVHIIDTATGREH-GWRSDERFLMLSSFKLLASALVLARAD -RGEESLERRILYRPQDLVSWSPVTEKHVGGELSLAQLCEATITTSDNTAANLILVSYGGP -AALTAFARRLGDTVTRLDRTEPALNRAASGEPLDTTTPRAMAHTVRKLLLGDALAPASRE -RLLDWLLANTTGGKSLRAGVPSGWRVGEKTGTAGD-DANDIGIAFPPQSAPLIVTAYLAE -SVTDGATREAALASVGRLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. MR-S7 TaxID=1268622 RepID=A0A0A1VEJ9_9BURK -----EREARRLEARLGGRLGMAVLDTDTGAFA-AHRGGERFALCSTFKLLLAAQILRRVD -ERRERLDARVHFGWGDLVEYSPRTEPHAGGAMTVAELCEAAMVLSDNTAANLLLRRQGGP -EGLTAWLRTLGDAHTRLDRTEPALNDVPPGEVRDTTTPLAMARTLQTLVLGDALAPASRE -RLQGWLLGNLTGDRRLRAGMPPGWRVGEKTGTAQ-GTGNDAGVVWPAQGAPAVVACYLTE -CPGAPALRDAAIAEAGALAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MOE7 TaxID=1961713 RepID=A0A1W5Y0W1_9ACTN ----AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD -HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGNTYARLALGNALDKADRT -RLTGWLLANTTGGKRLRAGLPDGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR -PAPDAEADDAVIAETAALL---- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB34_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGVPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000D45FA60 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAASVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase class A IMI/SME n=1 Tax=Pantoea sesami TaxID=1881110 RepID=A0A1M5YUC5_9GAMM ------DEIKSLETDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYSTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEVFRLDRWELDLNTAIPGDERDTSTPAAIGKSLENLALGNILSEREKE -TYQTWLKGNTTGATRIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NQKEAKHDDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. dk4132 TaxID=2662433 RepID=UPI001295D61E -----DEAFVALEKRYDARLGVFAIDTHTGETL-AHRADERFAYASTYKALAAAAVLARTE ---ARRWEEVVTYGADDLVTYSPVTEQHVGTGLSLRRIAEAAVRESDNTAGNLLLDELGGP -AGLQRALRGLGDDVTVVARRETALNDTSPGDRRDTSTPRAFAQVLQRYAVGDALRPPARR -TLLRWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRDPVVMVVFSDR -STADAEYDDALVAEAARVAL--- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A246I949_STEMA ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRMPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -SAISNEQRAGVLAQVGRIA---- ->[subseq from] Beta-lactamase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A233RME5_9ACTN ----TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKN ---LPQMERLVRYGKEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAAKQA -VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKIALEAf ->[subseq from] class A beta-lactamase n=1 Tax=Actinophytocola xanthii TaxID=1912961 RepID=UPI000947189E ------ARLRELEAGFGGRIGVAARR--GGRTL-HYRAGERFAMLSTAKALVVAAVLHRAP -CDPGLLDLVVRYGADDLVEHSPVTERHVDAGMTVEALCDAAIRQSDNTAANLLLRQLGGP -DDLTRFARFIGDRVTRLDRWETELNSNLPGDPRDTTTPAAMAADLEALVLGDVLAAEDRE -RLTGWLVGNTTGDARVRAGLP-GWRVGDKTGTGAYGAANDIGVAWPPSGPPLVLAVFTTR -PEEAAEPADEVVAEIARVVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. CB02488 TaxID=1703920 RepID=A0A1Q5N9Y0_9ACTN ---RTERAFRDLERKFDARLGVHTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLDKNS ---LRQMDRLVRYGRDDLVSASPVTERHVATGMTLRELSDAAIRYSDNTAANLLFHELGSP -RALQDALRALGDDVTRCDRYETALSDATPGDLRDTSTPRALATGLRAYVLGNILPADRRA -VLTDLLRRNTTGDNTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR -DAKDAERDDALIAGAAKVALD-- ->[subseq from] L2 beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF96_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATALSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=A0A379A6I6_9NOCA ----ATADLTALEQQYDAQLGLFAVDTGSGKTL-TNRADQRMPFLSTFKGLAAGALLKAHP -LATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP -QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERE -QLTKWLKANTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVLAIQTRK -STKTAEPSNDLVAAATKLVVDK- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI000DA9CB15 ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -HAVERWLRGIGDRTTRVDRVEPNLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPTWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=A0A1B2HAH3_9PSEU ---SITNRLRDLEEQHGARLGVFASDTGSGRTV-LYRSNERFPICSVFKTLAAGAVLRRDQ --DGSLLGKVIRYTQAEVDKYGPITGKNLANGMTVRALCEATITYSDNAAANFLLRELGGP -SAVTRFCRSIGDPVTRLDRWEPELNSAEPWQELDTTSPRAIGQTYARLTVGHALERPDAR -QLTDWLLANTTGANRLRAGLPGEWRLGDKTGTGSYGTTNDVGITWPPGRRPIVVAVLTTK -PDQKAGADEPLVAKAAGLVADAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces flavochromogenes TaxID=68199 RepID=UPI000AA1CBB4 ---DLVARLRELEERHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTFAVAAVLRDLD -HDGSFLARRIRYTAADVKRWSPRTEENLAHGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFARSIGDRTTRLDRWEPELNSAEPWRETDTSTPRAVGRSYGRLVLGDALPRRDRE -RLTGWMLANTTSGERFRKGLPADWVLADKTGGGRYGGNNDAGVTWPPDGGPIVLTVLSTR -FVEDAAPVDALVADAAALVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=A0A2W5HB30_DELAC --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTTNDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DvalAA-43 TaxID=1839762 RepID=A0A1C4R2U3_9ACTN -----DGQFKELERSFGARLGVYAVDTGTGREV-AYNDRARFAFASTFKAFAAGAVLRKDS ---VDGLDEVVTYSRDDLVSNSPVSEKHVGTGMNLGALCDAAVRFSDNTAANLLLDRLGGP -RGLDAVLAGIGDDVTRMEHQEPELNQWSPGAMADTSTPRALAGDLRAFVLGDVLGKDERA -QLTKWLRANATGDELIRAGMPKNWVIGDKTGAGGYGTRNDIAVVWRPDAAPIVVAILTNR -HKEDDAYDNALIARAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangdongense TaxID=1325090 RepID=UPI00112C9BBD ------PELEAYERASGGKVGVYAENLATGAKL-SWRADERFVMCSTFKASLAAAVLARVD -RGEEKLDAMIAYGKADLLDYAPAAKENLAAGMSVTDMCKAIVEISDNTCANLLLARIGGP -AALTTFWRSLGDQVSRLDHYEPELNRSPPGDPNDTTTPTAMVGNFRRLVIGDALSAKSRA -QLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG -GTPNAAQLQAVFASVGRMAAQ-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066E6A77 -----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATMLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. KBS0706 TaxID=2578109 RepID=A0A554UFV9_9MYCO ----AAARLAELERVHGGRLGVAALNLATGARI-GYRADERFLLCSTFKALAAAFVLARVD -RKQERLDRRIVFSRKDLVGKSVLEPRVGRAGATMAELCDAAVTYSDNTAGNLLLASFGGP -VGLTAFLRSLGDEVSRLDRIEPGLNAAGPGDPRDTTTPAAMLETLRKLLFGDALSPASRH -QLAAWLITNKTGDTRLRAGFPAGWLVGDKTGTGGEGSTNDVAVAWPPDRGTVIVTAYCEL -PSQTFEQRNPVVAEIGRIVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM43335 TaxID=2569853 RepID=UPI0012BA9570 -------RLIELERKFDARLGVYALATGTGATI-AHRADERFAFCSMFKVPAVAAVLHRNP ---LSHLDTVVRYTEDDLMRHSPVTRRHVDTGMTIRRLCDAAIRYSDGTAGNLLLRELGGP -AHVTAYARGIGDTVTRMDRVEPAITEATPGDPRDTTSPRAFGTGFHRIVLGDALTNDKRA -FLRDLLERNTTGAHRIRAVVPRGWTIANKTGTGDYGTLNDTAIVWPARTAPLVVTIMSGK -AARDAEYDEALIAEAAAYAM--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus hemicellulosilyticus JCM 9152 TaxID=1236971 RepID=W4QIQ0_9BACI ---TVEDTFSQLEEEYDARLGIYALDTGTGKTV-TYRSDERFIYASAHKPLAVGVLLQQKS ---MEELDEHITYSRDDLVNYNPITEHHVDSGLTLKELSDASIRYSDNTAANLIFHAIGGP -EGFKEGLRAIGDNVTEPERIEPDLNDVEPGEIQDTSTPEALAKSLQQFTLGDALSEDKQE -LLIDWLKRNTTGDDLIRAGVPEGWEVGDKTGSGSYGTRNDIGILWPPGRDPIILSVLTSK -EEQDADHDDTLIARATEEVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=UPI0001851576 ------ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP ---IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP -SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA -LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR -PGFRTPPSERLIAEAAERIV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Nocardioides sp. dk884 TaxID=2662361 RepID=A0A5Q0NS18_9ACTN -----DEAFVALEKRYDARLGVFAIDTHTGETL-AHRADERFAYASTYKALAAAAVLARTE ---ARRWEEVVTYGADDLVTYSPVTEQHVGTGLSLRRIAEAAVRESDNTAGNLLLDELGGP -AGLQRALRGLGDDVTVVARRETALNDTSPGDRRDTSTPRAFAQVLQRYAVGDALRPPARR -TLLRWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRDPVVMVVFSDR -STADAEYDDALVAEAARVAL--- ->[subseq from] Beta-lactamase n=2 Tax=Mesorhizobium TaxID=68287 RepID=A0A1A5QDV8_RHILI -------KIRRIEAKSGGRLGVACRIAGTGVQF-GYRENELFPICSTFKTLAAAFILHRVD -GGIEQLDRSMEVPHNAVVANSPTTKNHAGGAMTVAQLCEAAVTVSDNGAANLLLASFGGP -PQLTAYLRSIGDTVTRLDRIEPELNESVPGDPRDTTSPLAMIEDYERLALGDSLSQKSRA -QLVDWLVANKTGDDRIRAGLPKRWKCGDKTGTGEHGSTNDAAVIWPTSGNPVLMSLYLTG -TGQSLVKRNATIASVSRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura montaniterrae TaxID=1803903 RepID=UPI00124DD692 ---AVTEQLKALEKSRKDRIGAYAVDTGTGRFA-AYREDERFAFASTFKVMACGAVLRKAR -QDPGLMDRVVHYKKSDLVDNSPVTEKHVKTGMTLSALCKAAITQSDNTAGNLLLRQIGGP -AGDTAFLRSLGDRVTRHDRWETDLNLWKPGELRDTTTPRAWAGDLRSLTAGGALVRADRD -RLTGWMKQTVTGDHRIRAGLPKSWTVGDKTGTGGWGTANDIAIAWPPSGAPLIIVITTNR -LAAGAEADEPAVAKTASILAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces durhamensis TaxID=68194 RepID=UPI0007C65FFE ---GAEAELSDLERRHGARLGVYARNLRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG --DCAPLDKVIHYPPHDIISNSQHTAEHVDTGMTVAELCAAAIRYSDNAAGNLLLREIGGP -AGLTRFFRSLGDQVSRLDRWETDLGSAIPGDLRDTTTPQALGRSFERLTLGRALTGADRE -RLVGWLKGNTTSAARFRAGLPRDWVLADKTGTGDYGSANDIGVAWTTRGTPVLLTVLTAK -GAQHAPADDALVEEAARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE0C48 -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVHGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAADERNGIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Y36 TaxID=2035447 RepID=A0A2A6PPE8_9BRAD -------ELESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLEYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTLSRLDHNEPELNRSPPGDPRDTTTPMAMAGNLRRLVLGEALTPASRS -LLTEWMVNCKTGANRLRGGLPASWSIGDKTGNNGKDASGDIAVVWSKPETPILVTAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 190mf TaxID=1761798 RepID=UPI00089ED4C4 ----AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETLDRVVSYGAGDLLSYAPVTEACAGTGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA -RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WAC01526 TaxID=2588709 RepID=UPI0011E023F1 ---TFASAFKKLERKYDARLGVYAVDTDTGREV-AYKDGERFSYNSTFKALAAGAVLRKHS ---PSAMDRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP -KRLEGVLKGIGDDVTRMEHIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGDVLDKGDRK -QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR -FKKDADFDNKLIAEAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=A0A373F8W2_COMTE -----TKELAQLEVQSGGRLGLHMLDTATGLEA-GWRSQERFALCSTFKTLLAAQVLQAAQ -MGQLQLQRSYHYESAEVVPWSPITEKHVGAGMTLQQLCEAAVVVSDNTAANLLLKATGGP -ALLTNWLQTLGDSVTRLDRNEPELNTAIAGDERDTTTPAAMLRTLQKILLGNVLSEPHRA -LLQQWLVASRTGDKRLRAGMPADWKAGGKTGSGDNATANDTLIVWPKGTAPLLVTAYFTG -SKLDATGRDAVLAKAGEVVSRW- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI000344A358 ---TLAQRLAGIERRTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELSLQRPVQIRAVDMLSHAPVTERHVGGALSVAELCRATMIFSDNPAANLLFPLVGDP -PGLTRFLRELGDPVTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 8I-2 TaxID=2653136 RepID=A0A653V8P5_9MICO ---ATARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR -VLRDAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR -ADAAAEPSDALVAAATRAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas translucens pv. cerealis TaxID=152263 RepID=A0A514E9A6_XANCT --qTLAQRLAGIERGTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELSLQQRLPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTFGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDVLRPVSRQ -RLSEWMIDNRTGDACLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDDAARDAALKAVAVVVCE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE10127 -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARVD -RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAADERNGIVAEIGRVAA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. VV52 TaxID=2066958 RepID=UPI000C9E1FCE ------SDFAALEKASGGRLGVTLLNTATGARV-GHRQDERFPMCSTFKFALSATVLHLAD -KGTLSLDRRLPVRQQDMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRGHGDAVTRNDRLEPEMNDFAPGDPRDTTSPAAMAASLQRFVLGDVLSKPSRL -QLADWLIDNETGDARLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ASVDDAGRNDVLRQVAVI----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5755 TaxID=1519475 RepID=A0A0M8RM41_9ACTN ------PRLAALERKYDARLGVYALATGTGATV-THRADERFAFCSTFKGLAAAAVLHRHP ---LSYVNTVVTYTEADLMKHSPVTRKHVATGMTIRQLCDAAIRFSDGTAGNLLLREIGGP -GELTAFTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGDALAADKRA -FLRDLMERNMTGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK -STKDAAYDQTLIADAAAYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=A0A373FC25_COMTE ----WSHAMAQIEQDAQGRLGVAMLDTGSGLAL-GWRQDERFAMCSTFKLPLAAWVLALVD -QGRERLDARVQYSEAELVEYSPVSGPKAGARLTVGELCAATVSLSDNSAANVLLARHGGP -AALTAWLRSQGDSITRLDRNEPSLNEATVGDERDTTTPLAMLHTMQRLVLGNSLSPSSRA -TLQRWLIETSTGDQRLRAGAP-GWKVGDKTGTSGSGTANDIGVLWPPGGAPVLVSCYLTQ -STARPEQRDAAIAQVARAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB7835 -----EAQLATLESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATKPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP -GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTDVLTPASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI -PAIAADERNAIIGEIGRIAA--- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA40330 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIV------ ------------------------ ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-13 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A218KGD7_ENTAS ------DEIKSLETDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYSTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEVFRLDRWELDLNTAIPGDERDTSTPAAIGKSLENLALGNILSEREKE -TYQTWLKGNTTGATRIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NQKEAKHDDKVIAEASRIAID-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A CARB-5 n=1 Tax=Pseudomonas salegens TaxID=1434072 RepID=A0A1H2HJ22_9PSED ------TALDRVAEQLDARVGFSAYDLETGQRW-EYQANQRFPLSSTFKTLACADLLRRVD -KGEMDSSSKVHFSAADLVTYSPVTEHFAGRQMTLSALCEATLTLSDNTAANLILRALGGP -ASVTAFARFLGDGSTRLDRWETDLNEAQPGDPRDTTTPNAMVNNLHKLLLGDVLSVESRG -QLRNWLERNQVADGLFRAAVPEAWVVADRTGAGGFGSRSITAVMWPPDRQPIIVALYITD -TAASFSERNDAIADIGIAIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2W6G3S0_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPVSRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia veterana TaxID=132249 RepID=UPI00031B1831 -------ELHHLEARLRGRLGLYALDTGTGRTV-EYRADERFPYCSTFKALAAGALLSTLP ---PAELDRHVSYTRADLVPNSPITEPHVEQGLTLREILDAAVRFSDNTAGNLMFAELGGP -QGLQQRLRDIGDATTRMDRTETSLNEAVPGDERDTSTPRALAADLRHYVLDPSVAADDRE -VLTGMLRANTTGGALIRAAVPTDWQVGDKTGAGAYGTRNDVAVVWPPGRAPIVLAVLTTR -DRPDAEYDNAAVARAAAIAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. JV178 TaxID=858632 RepID=A0A2G9DHK0_9ACTN --------LRALEERYGARLGVYAHNVRTGETI-RHRADTLFPICSLFKTLAAAAVLRDLD -RDGEVLSRRIHYTAADLLENSDVTRDHLATGMTIAELCNAAIRHSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRTTDTTSPRAIGRTYARLVLGDTLGRPDRA -LLTHWLLHNQTSNTRLRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVLSLMSRK -FDQDATTENKLIADTAHLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009A047F0 ----VVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPMCSTSKAMAIGAVLRDLD -HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMSVADLCGAAVSYSDNTAMNLLLTELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGRTYARLALGNARDTADRT -RLTGWLVANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIVWPPGRGPIVMAVLSTR -PEPDAEMDDAVIAETAALL---- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora viridis TaxID=281105 RepID=A0A561SEL7_9ACTN ---SADAAFQQLEQHYGARLGVYVLDTGSGREL-RYRADERFAFASTAKTLSAGALLRTAS ---EAELDKVVRYSQQDLLAWAPVTSQHLATGMTVRDLLAAALDHSDNTAANLVTAELGGP -AAVQQTVRALGDTTTNVDRTEPTLNEATPGDPRDTSTPRQLATDLRTYALGDALPADRRT -QFTDWLVANTTGGPYIRAGVPAGWKVGDKTGNGDYGTRNDIAVVWPAGGAPLVVALLSDR -GKADAKSDDDLLAQATKTAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-1347 TaxID=1476877 RepID=UPI0004C55A06 -----ARAFKKLERKFDARLGVYALDTGTGREV-AYNDSRRFAYNSTFKALAAAEILRKYA ---PDGLEQVVKYSKDDLIANSPITEKHVDTGMTLRALCDAAVRYSDNTAANLMFDKLGGP -KGLDAALERIGDDVTRMDRVEPFLSRWVPGEKRDTSTPRALAKDLRAYVLGDVLAEPERA -QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPDAAPLVVAILSHR -GDKDAAPDDKLIAEAASVVA--- ->[subseq from] class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDBE850 --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRL----- ->[subseq from] class A beta-lactamase n=1 Tax=Halobacillus sp. Marseille-P3879 TaxID=2045014 RepID=UPI000C7A0826 ---DTNQKFAELEDKFDAQIGIYAIDMGTDQTI-EYRPEERFAFTSTYKALAAGTLLQQKS ---TAELKEVITYTEDDLVPYSPVTKENADEGMTLLELSEAAVRTSDNTAGNLLFEALGGP -EKFEMALRQIGDNVIEADRYEPELNEFTPGDSRDTSTPRALAASLQTFAVDDLLSNDKRK -LLVDWMRGNATGDTLIRAGAPEDWEVVDKSGAGSFGTRNDIAVVWPPNRDPIVMAIMSRH -DMEDAEYDDALIEQSAEVIFDIf ->[subseq from] Beta-lactamase n=1 Tax=Variovorax sp. OV329 TaxID=1882825 RepID=A0A1I4YTM8_9BURK ---QAAAALAEIERRSGGSLGLHAMDTGSGRTL-SHRGEERFAMASTFKLLLAAAVLHRND -QAAGVLDERLPVRKTDLIAHSPITSKHLQAGITAREACEATVQVSDNAAANLLLPLVGGP -EGLTTFVRECGDGVTRLDRTEPTLNTNLPGDLRDTTTPAAMARTTARLLTGDVLSGPSRT -QLKSWLEGASTGMARLRAGLPKDWRTGDKTGTGANGAANDVAVTWAPGRAPIVLAVYLNG -STQPPAVLDATHAQAAAVVAAFf ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia sp. WCHEs120001 TaxID=2529380 RepID=A0A4R0GZD4_9ENTR -------AVARLEEHLGARIGIAVVDTASGETV-SYRGDERFPLNSTHKALLCGAVLSKVD -KGELALNETTQFSQSELVPYSPVTSQFVAPSMSWRQLCSAAVSESDNTAANLVAKKLGGP -AAVTRFFADSGDSVTRLDRAEPELNSAVPGDLRDTTTPLAVSHTLQKLALGEVLTPRSRA -QLVQWIKEDKVADALLRSTLPKGWVIGDKTGAGGYGSRSIISIVWPKKGAPRIVSIYITD -TKATIAQSNDAIARIGKAIFS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-SSA 1 TaxID=2315329 RepID=A0A505D5T3_9ACTN -----TGELKELERKFDARLGVYAIDTGTGREL-AYRDGERFGYHSTFKALAAGAVLRKYK ---LTGMNEVIKYSKDDLVHHSPITEKHVETGMTLRELCDAAVRYSDNTAANLLFEALGGP -KALEAELRKLGDDVTVMERIEPGLSDWVPGEKRDSTTPRALAEGLRAYVLGDVLRKPERA -QLTKWLKTNKTGDELIRAGVPEGWVVGDKTGSGNYAGRNDIAVVWRPGAAPVVMAIMSNR -GKAEDTYDNKLIAEAATVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000CFD8B78 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGK----------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces alboviridis TaxID=67269 RepID=UPI000516B9C5 ----TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGAALPAEKQA -VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKVALEAf ->[subseq from] Beta-lactamase n=1 Tax=Amantichitinum ursilacus TaxID=857265 RepID=A0A0N1JTG1_9NEIS ---DLAAAMAALEHASDIRIGVSAFDTGNGKRF-DWRADERFAFCSTFKFMLAAAVLNERK -RQPRVLQERLLYTHKQLPAHSPITEKHVADGMIVSDLCKAAIEYSDNGAANALLRYLGGP -AKVTAFARKTGNASFRLDRMEPELNTSIPGDVRDTVTPADMARSLQTLVLGEALPEHERG -LLSEWLKGNTTGDKRIRAGVPAGWMVGDKTGTGAYGSTNDIAVLWPGNGAPICMAIYVGS -KHKDADPPETVLAEATRIALK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinopolyspora saharensis TaxID=995062 RepID=A0A1H0ZTD6_9ACTN ---EAKDRFAGLEQRFDARLGVYAVDTATGEEV-THRADERFAHASTYKALSAGVVLRRNS ---IGGLNRRIHYSRSDLVTYSPITKKHVDTGMTLRAVLDAAIRYSDNTAANLLFREIGGP -AALQAALRGIGDTTIHVDRTEPELNRRAPDDIRDTSTPRAMAETLRKFTVGDVLAPDKRA -ILNEMLRTAKLTGDLVRAGVPSGWEVGDKSGAAEYGTRNDIAVIRPPGRAPVVLAVMSDR -QSRDAEYDDALIAQAARQVVD-- ->[subseq from] Beta lactamase n=1 Tax=Xanthomonas translucens pv. graminis TaxID=134874 RepID=A0A1M4IEE6_XANCT --qTLAQRLAGIEWRTGGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDALQPASRQ -QLSAWMLDNRTGDACLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRMPLLLTAYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_018 TaxID=2175638 RepID=UPI000DA6DF7F ----TARVFAALEQRYDARLGVVAVDTGNGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGVGDRTTHVDRAEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNMTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR -ADPDAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001296F596 --hALEARLAELKRRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPLTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albofaciens TaxID=66866 RepID=UPI001239A2E3 -----HRRLAELERKYDARLGVYALATGTGATV-AHRADERFAFCSTFKGLAAAAVLHRHP ---LSHLDTIVTYTEADLMKHAPITRKHVTSGMTVGQVCDAAIRFSDGTAGNLLLREIGGP -GQLTAFTRSLGDTVTRMDRTEPAITEATPGDPRDTSSPRAFGTDYQKVVLGNVLAADKRA -FLRDLLERNETGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK -SAEDAAYDQALIAEAAEYVVH-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. S5 TaxID=1456735 RepID=UPI000EF8727F ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=2 Tax=Nitratireductor TaxID=245876 RepID=K2M8G9_9RHIZ ---ALLKRMDEVEKRVGGRLGAVIVDLETGRRW-SRRADERFPMNSTFKAFACAGVLARVD -AGEEDLGRRIAFGMRDLIHHSPVTEKRAGTRLTLAELCEATIGWSDNTAGNLVLDAIGGP -PGFTAFMRSLGDTRTRIDRREPELTQNTPGDPRDTTTPNAIVATLQALLLGDALSSASRG -RLERWMVEGKVTGPLLRSGLPEGWRIADKSGAGRRGSRGIVAVIWPPERQPVVAAIYMAE -CACSMAQRNAAIAAIAPALF--- ->[subseq from] Beta-lactamase n=1 Tax=Nitrincola tibetensis TaxID=2219697 RepID=A0A364NQZ1_9GAMM ---ALMTELQRIENVLDARIGFSAYDSETGVRW-EYNADQRFAMSSTFKTLACAALLQRVD -SNEEQLERKVSFSKSDLVTYSPITEQHADSRMSLFELCEATLTTSDNTAANLILQAIGGP -EVVTEFARGIGDNVTRLDRWETELNQATPNDDRDTTTPNAMVGNLKGLLLGDVLSPNSKS -QLREWLVGNKVADGLFRASMPAEWVIADRTGAGGFGSRAITAVIWPPERLPILVAFYITE -TTASFEDRNTAIAELGSVI---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A317BTB9_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDECFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=UPI0005827EC1 ------AALVEVERKFDARLGMFALNTATGVTV-THRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTIVRYGKGDLLKSAVITSQHVTTGMTIRDLCDAAIRYSDGTAGNLLLRELGGP -QQLTEYLRGLGDSVTRMDRTEPAIVEATPGDPRDTASPRALGTDYQKIVLGDVLPEDKRA -FLRDLLERNTTGAQRIRAGLPPDWRVADKTGTGDYGTINDIAVVWPPGAAPLVIAVMSSK -AAKDAKYDQALIAQAASHA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALC6_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus caseinilyticus TaxID=1503961 RepID=A0A1H3SLF4_9BACI ----ADEIFSKLEEEYDARLGIYALDTGTGETV-AYRADERFIYASTHKPLAVGVLLQQKS ---LEDLDQLITYSKDDLVNYNPITEKHVDSGMTLKELSDASIRYSDNTAANLIFQEIGGP -EGLKAGLRAIGDTVTEPARIEPDLNDVEPGEIQDTSTPEALAKSLQAFTLGDSLPADKQE -LMIDWLKRNTTGDDLIRSGVPEGWEVGDKTGSGSYGTRNDIAVIWPPEKEPVILAVLSSK -DNRDGEHSDELIARATEEVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI00056AD7C1 -----TGRLRALEEHYGARLGVYAHNVRTGKTI-RHRADTLFPICSLFKTLAAAAVLRDLD -RDGEVLARRIHYTAADLLDNSDVTKNHLATGMTIAELCDAAIRHSDNTAGNLLLRELGGP -TAITSFARSLGDPVTRLDRWETELNSGEPWRITDTTTPHAIGRTYARLVLGDALTRPDRA -LLTHWLLHNQTSNTRLRAGLPSSWTVADKTGGGSYATNNNAGIAWTQDGTPLILSIMSRK -FDQDATPENKLIADTAVVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3G1QBL9_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAV----------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces showdoensis TaxID=68268 RepID=A0A2P2GPS3_9ACTN -------DFQRLERAYGARLGVYAVDTGSGREV-LHNHTERFAYASTFKALAAAAVLRSHS ---PSGMGKVIRYSGEQPVDHSPVTEKHVETGMTLHELCDAAVRHSDNTAANLLFDALGGP -KGLAAALREVGDTTTVVERREPELNQWAPGATRDTTTPRAIAGDLRAFVLGDALGPAERA -QLTTWLRTNTTGDELIRAGVPAGWVVGDKSGAGDYGVRNDIAVLWPPDAAPIVMAIMSNR -GTEEADDDNGLIARAASVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI93-02 TaxID=1522757 RepID=A0A3N6F097_9ACTN -----EQAFGELEQKFDARVGVYAVDTGSGLTV-THRPDERFAYASTCKALLAGALLKTYT ---LPQLDRRVRYGPGDLVANSPVTEQHVDTGLTVRELCDAAVRHSDNAAANLLFQELGGP -GGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALAADLRAYALGSALGTDARA -VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR -DARDAEPQDALVAGAARVALDAf ->[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A2P1TJY4_CLOBO ---QYNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP -SGFKSALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQASKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Aquabacter cavernae TaxID=2496029 RepID=UPI000F8E42B0 ---QAEHACAAIEARTGGRLGVAVLDGTGAPRI-LHRAEERFPFCSTFKFLVAGAVLKRVD -EGKERLDRRIAYGTDDIIQHSPVTKANLGKGMSVADLCAATVTLSDNAAANLLLATLGGP -KGLTAMLRAIGDTVTRNDRWETALNSAIPGDPRDTTSPLAMARDIHALVVGDVLSPPSRT -LLATWLYDCKTGDDRLRAGLP-GWRVGDKTGTGGTGTVNDVGIAVPPGTRPIILSVYLTQ -SRLDLAGSNAAIAEVAALAA--- ->[subseq from] class A beta-lactamase n=2 Tax=Bradyrhizobium japonicum TaxID=375 RepID=UPI000419A075 -------ELESYERETGGRIGVYAENLATGAKL-AWRADEHFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARVGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKVPILIAAYTQG -GRPNAAQIEAVFARVGRMVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomycetospora succinea TaxID=663603 RepID=A0A4V3DB40_9PSEU -------ALAGLEQRSGRRIRLLALDTGTGRAV-GHRADERALMCSTAKVLIAAAVLRRAA -TEPGLLDRTIRYSRADLLDYAPTTERFVDTGMTVAALCEAALVVSDNTAANLLSALLGGP -AATTAFVRTLGDTTTRLDRLEPELNETAPGDERDTTTPAAMVADLRALVLGDALDPAGRD -RLTGWMVGAVTGTEQIRAGLPRDWRVGDKTGSGAQGENNDVAVAWPPGRAPWVIAVFTTP -TDPASTNGRATIADATRIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24085 TaxID=1709476 RepID=UPI0007C6FD31 ----VTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSVFKTLAAAAVLRDLD -RHGEVLARRIHYTEDDLVIGSDQTAAHLAEGMTIAGLAEVAITYSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRLTDTTSPYAVGRTYGRLVLGDALNRRDRE -LLTHWLLHNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDTGDPIVLSVLSTM -PAPDAVRDDALVADAAAVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium meliloti (strain SM11) TaxID=707241 RepID=F7XDI1_SINMM --hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIGFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRPSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM4349 TaxID=1040988 RepID=UPI00047772E5 ---DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTASRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLLTGEALSATSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GTPSAAQIETVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993) TaxID=1114943 RepID=I2N3E8_STRT9 -----GRAFAALEKEFAARLGVFAVDTGTGRTV-LHRPDERFAYASTCKAFIAAAMLRKFS ---LREMQRRVTYGPEVLQPHSPITERNVGKDMTLSELCDATVRYSDNAAANLLFDELGGP -RGLQTELRSVGDRVTRCDRYEVELSDAVPGDPRDTSTARALATDLRTYVLGNALPPEKRA -VLTDWLKRNTTGDNVIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWRPDAAPIAIAVLSRK -DVKGAEHQDALIARAAEVALNAf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2W6RB90_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLP----------GGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2U4H654_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAAILQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia endophytica TaxID=401976 RepID=A0A4V2PIW8_9PSEU ------AELAGIESRFGGRLGLYALDTGTGRAV-GHRADERFLMCSTTKVPLIALVLRRSV -EDTGLLDRRIRWTRDDLLEYAPVTTPNLATGMTVAELCAAAVTVSDNTAANLLFAQVGGP -QAVTAFVRGLGDPLSRFDRVEPALNDTAPGDGRDTTTPARFAETLRLLTLGDALPPPQRD -RLVGWMDAATTGAAQIRAGVPAGWRVGDKTGSGNRGESNDVGVVSAPGRAPIVVTVFTAP -SDPDSTAGKPTIAAATRAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_003 TaxID=2175637 RepID=UPI000D9F07ED ----TARVFAALEQRYDARLGVVAVDTGNGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGVGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNMTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR -ADPDAEPSDALVAAATRAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SAT1 TaxID=1849967 RepID=A0A1A9J530_9ACTN ----ATDALRALEERYSARLGVHARNTRTGQSV-AYRAGERFALCSTFKVFAAGAVLRDHA --SSAPLDKVVRYPDRDILLNSPVTQQHVGSGMTVGELCAAAIRHSDNCAGNLLLRELGGP -AGLTAFFRSLGDRVSRLDRWEPDLNSAGPGELRDSTTPQALGASLERLTVGDELSGAARE -QLLTWLKGNTTSARRFRAGLPKDWVVGDKTGTGDYASANDIGVAWTTRGTPLVLVVLTSR -DAPDAAVDEGLIADAAAVLAD-- ->[subseq from] Beta-lactamase n=2 Tax=Saliterribacillus persicus TaxID=930114 RepID=A0A368XBF0_9BACI ----TSSGFEELEKEYDAKLGVYAFNTGNNQSI-SYRADERFGYTSTHKALAVGALLKKKS ---SDDLDEKINFTEEDLVNYNPVTEKYVDTGMTLKELSDASLRYSDNTAGNLILEAIGGP -KGFKDVLREIGDDVTEPARIEPELNNVEPGETKDTSTPKALAESLQAFTLGDVLSEEKQK -LLNDWLKRNTTGDNLIREGVPEGWIVGDKTGAGPYGTRNDIAVIWPPDDSPIVLAILSRR -EKADAEYDDELIAKATKVAIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE1DDE1 -----EAELAALESRHPGRICVSILDMASGKRI-EHRAHERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAAGERNGIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03911 TaxID=1804758 RepID=A0A1Q4X2A1_9ACTN ----ITDRLRALEQAHGARLGVFVWDTVTGRTV-LHRADELFPMCSTFKTIAVAAVLRDLD -RDGAFLAHRIRYTERDVTAYAPVTGLNLADGMTVADLCAAAVDHSDNAAANLLLRRLGGP -GAVTRFCRSVGDDVTRLDRWEPELNSAEPGRVTDTSSPRAIGRTYARLTLGGALRPGDAR -RLTGWLLGNTTGTNRLRAGLPADWTVADKTGTGAYGSTNDVGIVRPPGRGPVVMAVLSTK -DEAAAPADEPLVAGAAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ScaeMP-6W TaxID=1839779 RepID=A0A1C4NYX3_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALDPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea latae TaxID=1964541 RepID=A0A1V9DKL4_9GAMM ----LAAVAQQEEQTLKARIGIAVIDTGTSHVA-SYRGNERFPLNSTHKALLCGMLLNEQE -KGKLRLTERTQFDRAALVTYSPVSEKFVAPAMSLQQLCSAAISYSDNTAANLIAEKLGGP -AAVTRFFAHLGDKVTRLDRHEPELNSAIPGDVRDTTTPLAISETLRKLTLGEALTPVSRA -QLLQWMHDDKVADALLRSVLPAGWRIADKTGAGEYGSRSIVSVVWPENGKPLIVSVYVTQ -TEATLAQSNAAIARIGKAIFA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. LUP30 TaxID=1890285 RepID=UPI000851FCF8 ----VTARLRDLEARHGARLGVFACNVRTRRQV-RHRADELFPVCSLFKTLAVAAVLRDLP ---SSAPDRRIHYTADDLVENSEITKDHVADGMTIAELSAAAIQHSDNTAGNLLLRELGGP -AAVTRFARSVGDRVTRLDRWEPELNSAEPGRITDTTSPYAIARTYARLVLGDALSAPDRR -RLTDWMLGTVTSANRFRAGLPATWTIADKTGGGSYGANNDAGIAWTPDGAPVVLAVQLTK -PDREAPYDHALIVETAGVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID4956 TaxID=2690290 RepID=UPI00136F17A3 -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDHRP ---GARLDERIPYGTADLVPYSPVTEKHTGEGMTLRQLCDAAVRYSDNTAGNLL-RDIGGP -RGLTAYARRLGDRVTRLDHTEPELNGNPPGDPRDTTTPRAIAADYRALALGDALPAAGRT -LLTDWLVRNTTGDRRIRAAAPRGWRVGDKTGGGEYGRGNDVAVLWPGGRPPLVLSVLTER -PGRAATPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Paenibacillus terrae TaxID=159743 RepID=G7VP75_PAETH ------VVFKQLEIKFDARLGVYVIDTGTGKEV-AYRADKRFAYASTYKALAAGAVLQQKS ---NDELGKVINFAKDDLVTYSPITEQHVDTGMNLKEISDAAIRYSDNTAGNLLLKALGGP -EGFEKAMRDNGDTVVMANRYETELNEAIPGDHCDTSTPNALANSLKVLTIDDSMPNDKQE -LLIGWLKENTTGDELIRAAVPEGWVVGDKTGAGSYGTRNDVAIVWPPYREPIIIAVMSSR -DTEDAEYNNALIAEAAKAAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Franconibacter helveticus TaxID=357240 RepID=UPI00069DA441 ---ALTAAAQQEEKTLNARIGVTVLDTVTGKTL-SYRGDERFPLNSTHKPLLCGALLKQAQ -EKKIRLTDSVLFDKSQLVDYSPVTEKHVSPQMNWLQLCSAAVSYSDNTAANLISQKAGGP -QAITAFVRASGDNITRLDRFEPELNEARPGDERDTTTPDAISHTLQKLLLGDVLSEASRQ -QLTRWMAEDKVADALLRKSLPKGWKIADKTGAGGYGSRSIISMVWPEKGAPMVVAIYITR -TEASLTQSNDAIARLGGVIF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces qinglanensis TaxID=943816 RepID=A0A1H9R4Z9_9ACTN --qQAAAAFRKLERTYDARLGVYAVDTGTGREI-SFHAGERFAYASTHKAFTAAAVLDKRS ---VNGLDKVITYRKEDLLPHSPVTSEHVEEGMTLRALCAAALRQSDNAADNLLLRELGGP -EALDAFLEKLGDDVTNVNRYEPELNEATPGDDRDTTTPRAWTADLRAVALGDGLSKKERA -RLDTWMRNSPTGKTLIRAGVPEEWRVSDKSGGGHYATRSDIAVVRPPGRAPLVVTVMSKR -TEQDAEYDDRLVAEAASVVADE- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces badius TaxID=1941 RepID=BLAC_STRBA -------DFKKLEREFDARLGVYAIDTGTGREV-THNDRARFAYHSTFKALQAAVVLSTYS ---LDGLDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDRAAGP -KGLDASLEKLGDDITRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALRAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPDDELIAEAASVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. HMWF029 TaxID=2056863 RepID=A0A2R7MJ63_9BURK ---AWNDALVTIERSAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKEQLDSRVHYAATEVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDGTTRLDRTEPALNEAAVGDPRDTTTPLAMLHTLQKLVLGDALSIPSRA -WLQRWLAETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDIGVMWPPGGAPVLVTCYLTR -SAAAPEQRDAAIAQVARAVVA-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI000BAE1609 ---DAERRLAGLERASGARLGVYAYETGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLAAGMTVEELCKVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRATDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI000BB61ED5 ---DAERRLAGLERASGARLGVYAYETGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLAAGMTVEELCKVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRATDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=UPI000D982E9E ---EVTERIKRLEAARHTRIGAFAIDSGTGRFV-GHRADESFPFASTFKAMACGAVLRKAR -QAPGLLDKVIHYTKDDLVEYSPVTEQHVDTGMTVADLCHAAITQSDNTAGNLVLRQIGGP -AGLTAFLRTLGDRVSRSDRWETALNDWRPGEKRDTTAPRPWANDLRALTTGDALVPADRR -RLIGWMKATVTGDKRIRAGLPKSWTVGDKTGTAGYGNANDIAIAYPKSGAPLIIVITTTR -PGAEDEADETSIARTATILAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CNPSo 3426 TaxID=2560054 RepID=A0A4Y9P9N6_9BRAD -----PAELESYERESGGRVGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIDDNTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGDALSPASRA -LLTEWMVNCKTGANRLRGGLPASWTIGDKTGNNGKDAAGDIAVVWPKPDTPILITAYVQG -GAPNAAQIEAAFARIGRTVA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=A0A1I5CVJ3_9ACTN ---EVTERIKRLEAARHTRIGAFAIDSGTGRFV-GHRADESFPFASTFKAMACGAVLRKAR -QAPGLLDKVIHYTKDDLVEYSPVTEQHVDTGMTVADLCHAAITQSDNTAGNLVLRQIGGP -AGLTAFLRTLGDRVSRSDRWETALNDWRPGEKRDTTAPRPWANDLRALTTGDALVPADRR -RLIGWMKATVTGDKRIRAGLPKSWTVGDKTGTAGYGNANDIAIAYPKSGAPLIIVITTTR -PGAEDEADETSIARTATILAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A5H2UPA5_9ACTN -----GRAFAALEKEFAARLGVFAVDTGTGRTV-LHRPDERFAYASTCKAFIAAAMLRKFS ---LREMQRRVTYGPEVLQPHSPITERNVGKDMTLSELCDATVRYSDNAAANLLFDELGGP -RGLQTELRSVGDRVTRCDRYEVELSDAVPGDPRDTSTARALATDLRTYVLGNALPPEKRA -VLTDWLKRNTTGDNVIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWRPDAAPIAIAVLSRK -DVKGAEHQDALIARAAEVALNAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A2A2UAL0_9ACTN ---DAERRLAGLERASGARLGVYAYETGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLAAGMTVEELCKVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRATDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTTK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI00099712FE ----AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHQANERFPLCSTSKTMAIGAVLRDLD -HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDRADRT -RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR -PEPDAEADDAVIAETAALL---- ->[subseq from] Beta-lactamase n=1 Tax=Azoarcus sp. KH32C TaxID=748247 RepID=H0Q498_9RHOO --eAIQARLRELETAAQGRLGIHIFDSATGQEY-GYRSDERFMMLSSFKLLASALVLHRVD -VGQESLDRRIAYTKDDLVPWSPITEKHADGRMTLGELCEATITTSDNTAANLILASYGGP -PALTAYARLLGDGITRLDRFEPQLNEGHADKLLDTTTPRAMLSTMQMLVLGDSLSAASRL -RMQQWLLANTTGGKRLKAGLPGDWRIGDKTGTNGT-AANDIGVIWPANRAPILVAAYLAE -SEAASHERDAALAAVGTLI---- ->[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter agariperforans TaxID=268404 RepID=UPI00101C47CE -----VERLTAIRSRIGGRLGAYVLDTHTGRRF-GLDYDERFAMASTFKWLLAAAVLAKVE -RAELRLEQRVSFAEKDLLAHAPVTSKHLRQSLTLRELCAAVVEVSDNTAANLLLRLIEGP -EGLTKFARASGDEMTRLDRTELALNSNLPGDPRDTTTPRAMVGSMERVLLGTVLSEPSRQ -ILIQWMINSSTGLQRIRAGLPAHWKVGDKTGTGASGAVNDLAMVWPPGRKPILMAVYMSE -STETVETLSAAHAQVAAEVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Diaminobutyricimonas aerilata TaxID=1162967 RepID=A0A2M9CHK2_9MICO ----IASAMAALEQQYGARLGVYAIDTGSGAEA-AHRADERFAFASTIKVLAAGALLATRS ---DEELDQPVPVP-SRLEYWSPITEQHAGGTMTAREVAAAAASYSDNTAANLLFDLLGGP -AGLEAELREVGDTTIEVERTEPGLNEATPGDPRDTTTPRAFAATLRAYVLGDALDDTDRA -QLVEWMRGNTTGDALIRAGVPAGWTVGDRTGNAAYGTRNDVAVLWPDDGEPIVLVIMSSK -NAQDAEHDDALIADATRAVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus methanolicus TaxID=1471 RepID=UPI0012484B70 ---STTEQFKQLEEEFAARLGVYVIDTETNRTI-TYRADERFAYTSTFKPFAAAFILQKST ---ISELNKLKTFTTNDLVTYSPITEKHVQTGMNLLEISEAAIQYSDNTAGNLLLEELEGP -KELQQALRKIGDQTTSVDRYETELNEATPGDSRDTSTPRALAKNLQYVGLDEFLSESKKD -IFQDWLKGNTTGDSLIRAGVPKDWVVGDKSGAGGYGTRNDIAIVWPPERKPIIMVIMSSK -DEVEATYNDELIANTAKVIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YC419 TaxID=1775131 RepID=UPI0013E9DC12 ----FTGELKELESKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS ---LNGMNKVIKYSSDDLVANSPITEKHVESGMTLRELCDAAVRYSDNTAANLLFDALGGP -KGLEADLRKLGDKVTLMERIEPHLSDWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA -QLATWLKTNTTGNEVIRAGVPKGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR -GKAEDVHDNKLIAEAASVVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=A0A4R2R275_9PSEU -------ELSTLESENGRRIGVYARHTGTGETV-AHRADERFLMCSTAKLLAASAILKQHE -QQPDLLDKVIHYDREVLMPYSEITEQHVDKGMTVAELAAASITHSDNAAMNLLLDELGGP -SVVTDFVRDLGDEVTRLDRIEPHLNVSAPGDERDTTTPERIGSDLRALALGDALAEQGRA -RLVRWLRGNTTGDKSIKAGLPRDWQVGDKTGSGNNGEVNDVAVAWPPDGDPLIIAVYTAP -DGAERDNGYETVAAAAKIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pantoea sp. YU22 TaxID=2497684 RepID=A0A432B719_9GAMM ----LATVAKQEEQALKARIGIAVIDTATGSVT-RYRGDERFPLNSTHKALLCGALLSQQD -KGRLMLSERTQFDRAALVTWSPVTEKSVAPAMSWQQLCHAAIAYSDNTAANLIAKKLGGQ -AAVTRFFADLGDKVTRLDRFEPELNSAIPGDMRDTTTPVAVSETLQKLTLGEALKPASRA -QLVQWMRDDRVAGALLRSVLPAGWSIADKTGAGEYGSRSIISVVWPENGKPLIVAIYVTQ -TEATLAQSNAAIARIGKAIFA-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. EGI 650086 TaxID=1840409 RepID=UPI00131D14D1 ---AARAELSALEARFGGRLGVYAVDTGSGAAV-GHRADERFLLCSTLKTLVVSAILRSHQ -RQPGLLDRVIHYDRAQLLSHAPVTSRHVADGMTVAALCEAAITQSDNTAANLLFQVLGGP -PAVTDFARSLGDPLTRADRTEPELNVSAPGDERDTSTPARMAADLRALALGDALDPAGRE -LLGGWLRANVTGGKSIRAGLPAGWPVGDKTGSGAQGEVNDVAVVWPPGRAPLVIAVYTAP -ADPKATTGYATVAGATTIAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB03911 TaxID=1804758 RepID=UPI00093BEA6F ----ITDRLRALEQAHGARLGVFVWDTVTGRTV-LHRADELFPMCSTFKTIAVAAVLRDLD -RDGAFLAHRIRYTERDVTAYAPVTGLNLADGMTVADLCAAAVDHSDNAAANLLLRRLGGP -GAVTRFCRSVGDDVTRLDRWEPELNSAEPGRVTDTSSPRAIGRTYARLTLGGALRPGDAR -RLTGWLLGNTTGTNRLRAGLPADWTVADKTGTGAYGSTNDVGIVRPPGRGPVVMAVLSTK -DEAAAPADEPLVAGAAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140B54BF --eDLTEQFEELEDGYDARLGVYALDTGTGQEI-TYRPDERFAYASTFKILLCAVVLQQNS ---VDDLERVITYTEDDLQAHAPVTSEHLDTGLTIRELCDATTKYGDNTAANLLLDEVGGP -EGLGDALREIGDDTISVDRYAPELSDAVPGDTRDTTTPRALAASLQTFVLDDTLPEEKRE -LLVEWLVGNTAADDLIRAGVPDDWTVGDRTGAGGYGTRNCIGVVWPPGRDPIVMVFLSTR -ETEGAERDDQLIAAAAEVIAEAf ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522G2Y2_9GAMM ---AAQAQLAELEHRHGGRLGVAILDVAGTRRV-GYRADERFLMCSTHKVLTVGAVLARVD -AGREQLDRRMIFGRDALLAWAPVTSKHVGAPLSVGELCAAAITVSDNTADNLLLTSLGGP -HAVTAFARKLGDRLTRLDRFEPELNQGAPGDLRDTTTPNAMLGSLHALLLGDALSAASRA -QLATWLRAASTGRGRLRAGVPHDWIAGDKTGTGPHGESGDVAILWPPHRKPLLVAAYYVN -PDLGADSPDPVFAAVGRIAA--- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI001011B42B ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 275MFSha3.1 TaxID=1502746 RepID=UPI0008A7C60D ----AEPDWAAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETVDRVVSYGAGDLLSYAPVTRKALEAGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMLATLGRVLLGTVLSAASRA -RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=UPI001053AEB0 -------ELSTLESENGRRIGVYARHTGTGETV-AHRADERFLMCSTAKLLAASAILKQHE -QQPDLLDKVIHYDREVLMPYSEITEQHVDKGMTVAELAAASITHSDNAAMNLLLDELGGP -SVVTDFVRDLGDEVTRLDRIEPHLNVSAPGDERDTTTPERIGSDLRALALGDALAEQGRA -RLVRWLRGNTTGDKSIKAGLPRDWQVGDKTGSGNNGEVNDVAVAWPPDGDPLIIAVYTAP -DGAERDNGYETVAAAAKIAAE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000D6780E0 -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPGGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aureus TaxID=193461 RepID=UPI00099E9043 ---DLVARLRELEERHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTFAVAAVLRDLD -HDGSFLARRIRYTDADVKRWSPRTEENLANGMTVAELCDATLRFSDNTAANLLLRELGGP -TSVTRFARSIGDRTTRLDRWEPELNSAEPWRETDTSTPRAVGRSYGRLVLGDALPRRDRE -RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDAGITWPPDGGPIVLTVLTTR -FVEDAAPVDALVADAAALVAA-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0010202A3B ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAVVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas desiccabilis TaxID=429134 RepID=A0A4Q2IWF2_9SPHN ------DPLAAIASEAGGRLGVSVLDTGTGRRL-WLDPLARYPLCSTFKVPLAAAILARAD -RGELDVQRPIRFTQGDLLEYAPVVRENLSRGMTLAELCAAAIEWSDNAAANLLLPQLGGP -SGLTRFLRSAGDSITRLDRVEPELNEYKPGELRDTTTPMAMTTLLAALLTGDVLQPTSRK -QLADWMIGSRTGDKRLRAGLPKGWRVGDKTGTSGNGQANDIAIAWPPNRKPILIACYLDA -PGIAPEKADRAIASVGALVGQL- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella sp. ALI-6-A TaxID=1933817 RepID=A0A1V2PE25_9ACTN -----AADFQRLESRFAARLGVYAVDTGTGREI-AHNADARFPYASTFKALAAGAVLRKNK ---LAGMNKVVKYSTSDLEPNSPVAEKHVATGMTLLALSDAAVRYSDNTAANLLFAELGGP -KGLEAILRELGDNVTSMVRDEPEMSDWDPKNPRDTSTPRAFAKNLRAMVLGDALAKPERD -QLITWLKTNTTGAELIRAGVPKSWVVGDKTGTAGYGGRNDIAVIWPPGRSPIVVAVFSNR -RAPEAEPDNRLVAEAAKVVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia alexandrii TaxID=388408 RepID=UPI0006E1C826 -------VAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACAALLERVD -KKQSSLDQRTIITGDMIVSYSPVTENYINTAMTLADHCEATVTISDNTSANIILDELGGP -IGVTTYMRSIGDDVTRLDRNEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK -QLMQWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE -NEAEFQARNKAIAEIGAAFK--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. UNCCL125 TaxID=1502759 RepID=A0A1I7L6C5_9RHIZ ------PDWGTLERRLDGRLGIAAA-TADRVLA-AYRADARFPMCSTFKVLAVAAVLARVD -TGRETLDRIVAYGSGDLLSYAPVTRKALEAGMTVSDLCAAAIVWSDNSAANLLLASLGGP -EALTAWLRGTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRASLGRILLGTVLSPASRG -RLEAWMIACETGRKRLRAGLPPDWIVGDKTGSGDNGSVNDIAILRPPGRAPVVVAVYVTG -STASPETYEAAYAEIGRLIA--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium haemophilum TaxID=29311 RepID=A0A0I9YWN3_9MYCO ----LSQSFAALERKYDARLGVYALSTTTATTI-AYRADERFAFCSTFKAPLAAAVLQGHP ---VAYLDTVISYRQDAIHAASPITEQHVETGMTIGQLCDAATRYSDNTAANLLLNDIGGP -AGFTTYLRSLGDTVSRLDQAEPEMNRNPPGDERDTTTPRAVGGVLQKLILGDALTSDKRA -MLTDWMVRNTTGNKRIRAGFPADWKIADRTGSGDYGRANAIAVVWSPAGAPSVVAIMSDR -NGYEAQPSDALIADAAAGVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A125PVM5_XANCT --qTLAQRLAGIERRTGGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLPVRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=UPI000984127E -----SEAFKKLEDEFDVKLGVYAIDTGSNKEI-NYQENDRFAYASTFKPLAVGAILQTKS ---DPELQEVIRYTEEDLVTYSPITEKHVDEGMTLLEISDAAIRYSDNTAANLLLEAIGGP -DELETKLRDIGDETIEVDRYETELNEATPGDIRDTSTPKAMANSLQQYVLEDVLDADRRE -ILTNMLINNTTGDALIRAGVPEGWTVGDKTGAGGYGTRNDIGIIWPEDNEPIVIAIMSSR -DVEDADYDDKLIEKATKVVVKE- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_016 TaxID=2175644 RepID=A0A2W1TKI9_9MICO ---ATARAFAALERRYDARLGVAAIDTGSGRKI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTTEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -EAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTMLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDELVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Lentibacillus amyloliquefaciens TaxID=1472767 RepID=A0A0U3WIM7_9BACI ------EKFVQLENEFDAQISVYAMDTGTNQTI-EYRPNERFAYSSTFKPLAAAILLKQNN ---IENLEKVVTYTNDDLVTYSPVTEKHVDAGLTLLEISEAAIRKSDNTAGNLLLEAIGGP -DKFEHALRDIGDDVTQPERYETELNEFTPGNKRDTSTPRAMATNLKKVALGDFLPDDKRE -LLIDWMTGNESGDPLIRAGAPEKWTVVDKSGAGTYGTRNDIAVVWPPNKEPIVIAIMSRH -DTENAEYDDALIAKAAEITLNAf ->[subseq from] Beta-lactamase class A n=2 Tax=Labrenzia alexandrii TaxID=388408 RepID=A0A5E8H1I6_LABAD -------VAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACTALLERVD -KKQTILDQRTIITGDMIVSYSPVTENHINTAMTLADHCEATITISDNTSANIILEELGGP -NGVTTYMRSIGDDVTRLDRNEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK -QLMQWLEANKVGDATLRAGLPHDWRIADKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE -NEAEFQARNKAIAEIGAAFK--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinotalea ferrariae TaxID=1386098 RepID=UPI0012DCA0CE -------ALADLEASFDARLGVVAVDTGSGRRV-EHRADERFAYASTIKALLAAAVLDSTT ---DEELDEVIRFTSSDLVTYSPVTEDRVGEGMTRRELADAAVRFSDNTAANLLLEDLGGP -EALARALRAVGDDVTLPVRTEPALNEAVPGDDRDTSTPRALAASLRAFAVDDALSATDRQ -VLNGWLQGNTTGDELIRAGVPAGWLVGDKTGSGGYGTRNDIAVITPPGRPPIVLAVLSDK -GEVDAESDPALIAAATRVALE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-C151 TaxID=2580423 RepID=A0A5R9F963_9ACTN -----TGELKELERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKALAAGAVLRKYR ---LTGMNEVIKYSKDDLVHNSPVTEKHVETGMTLRELCDAAVRYSDNTAANLLFDALGGP -KGLEAQLRKLGDDVTMMERVEPGLSDWGPGEKRDSTTPRALAKDLRAYVLGEILRKPERA -ELTKWLKTNKTGDELIRAGVPEGWVVGDKTGAGGYGGRNDIAVVWRPGAAPIVMAIMSNR -DKAEDTYDNKLIAEAATVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520FI32_RHOSO ---SLDAKIDELEARYSTRIGVTAVDPTTGVTY-SHRGDERFAMCSTFKAYASAAVLRATE -DGSVSLDKAVVIEPGDLVENSPVTAAAAGTRMSLGQIAEAALTQSDNTAGNYLLREIGGP -AAITALARDLGDESTRLDRWETELNTAFRGDPRDTTTPNGLAQGVRALLLGDALDTASRE -QLLDWMRASKTSDKRMRAGLPPGWTAADKTGGGGFGTANDAGVAWTPDGNPIVLTLLTDS -LTEDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI00082F6043 ------ARMRELEREYDARLGVFALDTGTGRTV-AHRADELFPVCSVSKTLAVGAVLRDLD -RDGEYLARRVRYTEDDVKTHIPVTGANIANGLTVEELCAAAVSYSDNGAMNLLMRGLGGP -AAVTRFCRSLGDPTTRLDRWEPDLNSAEPGRVTDTTSPRAIGQTYARLAVGRALDAGDRK -RLAGWLVANTTGDARIRAGVPAGWTVGDKTGTGRYGTTNDVGIAWPQDRAPIALAFLSTR -QEQDAKAVDGLIAEATALAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rishiriensis TaxID=68264 RepID=UPI000D5A1B30 ----VTARLRDLESRHGARLGVFAYNVRTRRRV-RHRADELFPVCSLFKTLAVAAVLRDLD ---AAAQDRRIHYTADDLVENSEITKDHVADGMTIAELSAAAIQHSDNTAGNLLLRELGGP -AAITRFARSVGDRVTRLDRWEPELNSAEPGRITDTTSPYAIARTYARLVLGDALSAPDRR -RLTDWMLGTVTSANRFRAGLPPTWTVADKTGGGWYGADNDAGIAWTPDGAPVVLAVQLTE -PDREAPYDHALIVETAGVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=UPI000BC3095E --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bikiniensis TaxID=1896 RepID=UPI0004BFA31D ----HRREFRALESAFDARLGVYAIDTGTGREI-AYRDGERFPYASTFKALAAGAVLREEE ---LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELGGP -KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SDREAEPDNRLIARAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Delftia sp. JD2 TaxID=469553 RepID=A0A1C7LIZ1_9BURK --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] Beta-lactamase n=6 Tax=Delftia TaxID=80865 RepID=A0A1I0X5A2_9BURK --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium neotropicale TaxID=1497615 RepID=A0A176Z6A1_9BRAD -------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLSATIPYSQADLLEYAPVARQNLAAGMSVADMCKAIVELSDNTCANLLLARVGGP -AALTAFWRTIGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVLGESLSPASRG -QLTDWMVNCKTGANRLRDGLPGTWKIGDKTGNNGKDASGDLALVWPSPDKPLVIAAYTQG -GTPSPAQIEAVFARTGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Ruegeria sp. A3M17 TaxID=2267229 RepID=A0A366X5I3_9RHOB --qTLTETVQRWERRLDARIGLLLYDPSNEWEV-SYRADELFPMSSTFKPLLCGAVLAEVD -AGTESLSDHVTYQSTDLVDYSPVTSKHVETGMTVGALCEATMTISDNAAANLLLRHLDGP -AGLTEFLRTNGDDITRLDRWETALNEATPGDPRDTTTPRAILATLDRLLFGRALSPASST -QLRQWMIDDQVADGLIRAQVPDGWTIGDKTGAGGHGSRAIVAFLQTPGPRTYLAAIYLTE -SDAPLPERNAVLSDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Hyphomicrobium sulfonivorans TaxID=121290 RepID=A0A109B9J3_HYPSL ---DVEARLAEIAQNAKGRLGVTIIDTQTGERY-GHHWNERFPMCSTFKLLAGAFVLDRGD -HDEDNIDRKIKFTADDIIDHSPITKDRVGGDMTLRELAQAAVTHSDNTAANLVLDNVGGP -QGLTAYLRSLGDAATRLDRKEPDLNEVPKGDPRDGTVPRVISSTVHRILLGNVLSNTSRD -QLTEWLKASTTGKERIQAGLKDGWTAAGKTGTCANGSTNELAIIYPPNRDPIIAAVFLTD -SDASLDDRNKVLAEVGRTISDMy ->[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A2K9MRW1_CLOBO ---QYNSAFSQLESDYDVKLGIYALDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP -SGFKSALNQIGDNVTQPARIEPELNEAMPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQVSKIVFDSf ->[subseq from] class A beta-lactamase n=1 Tax=Delftia sp. GW456-R20 TaxID=1827145 RepID=UPI0007AE3B98 --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Delftia sp. CH05 TaxID=2692194 RepID=UPI00135E9C20 --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00099D274F --------LRALEREYGARLGVYALDTATGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD -HDGAHLAKRIHYTPQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNAAGNLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE -LLDRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPMVLAVLSTM -PEATAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Labrenzia alexandrii TaxID=388408 RepID=A0A0M6ZPT8_9RHOB -------VAKAIESRLNTRIGVAVFDPASGLNW-NYNGDDRFPMNSTMKAFACAALLERVD -KKQSSLDQRTIITGDMIVSYSPVTENYINTAMTLADHCEATVTISDNTSANIILDELGGP -IGVTTYMRSIGDDVTRLDRNEPSLNEGTPGDPRDTTTPVAAAQSLYKVLFSDELSASSRK -QLMQWLEANKVGDATLRAGLPHDWRIGDKTGAGAYGSRGNIAIIWPPNHTPVALAVYVTE -NEAEFQARNKAIAEIGAAFK--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis antarctica TaxID=1854586 RepID=A0A263D103_9PSEU -----RERLAELERRFDARLGLYALDTGSGSAI-EYRADERFAFCSTFKGLAVAAVLSRNP ---PSHVDTVVTYTEDDLLKSAVVTEEHVATGMTIGGLCDAAIRYSDGTAANLLVRDLGGP -AELTEYARGLGDTVTRMDRIEPAITEAIPGDPRDTTSPRAFAADYRAMVLGEALPAGSRD -FLRDLLERNTTGAKRIRAGVPDDWVVADKTGTGDYGTVNDIAIVWPPGSAPLVIAAMSSK -ATRDAGYEEALLAEAAAHVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Variovorax sp. BK119 TaxID=2512129 RepID=A0A4Q7SPK9_9BURK ----ALSALAAIERRSGGRMGLHAIDTGSGRTL-GHRAGERFAMASTFKLLLAAAVLHRED -RSPGLLDQRLPVRQADLITHSPVTSRHLAAGITAREACEATVQVSDNAAANLLLPLVDGP -AGLTAFVRECGDVLTRLDRNEPALNTNLPGDPRDTTTPAAMAGTTQRLLTGPVLSAASRD -QLRGWLEAASTGMARLRAGLPKDWRTGDKTGTGANGAANDVAITWPPGRAPIVLAVYLDG -STQPAPVLDATHAQAAAVVAARf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1A3JVD1_MYCGO ---DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRADERFALCSTFKAPLVAAVLHQYP ---LTYLDQRVTFSKADISSPSPIAEQHIDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP -AGFTAYLRSLGDSTSRLDHGEPELNRDPPGDERDTTTPHAIAVAIQQLVLGDALPQDKRA -MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI -AGYDAQPNEAFVADAARVVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces specialis TaxID=498367 RepID=UPI00099E5E3F -----ARAFRELEGEFDARLGVYALDTGTGREV-AYQEDERFAFASTFKALLAGAVLQEYG ---LDGLDEVVTYSSGDLIANSPVTENFTETGMSLRELCAATLWYSDNTAANLLLDALGGP -DALEAVLEEHGDDVTEMDRYEPELSDGVPGDIRDTSTPRAMAGNLRAFLLGDALERDERE -LLTRWMTTNTTGETLIPAGLPDGWTVADKSGTAGYGGRNDIAVIWPDDGNPIVMAVMSSR -DEEGAERDDELIARAATVALE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4T7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGK----------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM1417 TaxID=754500 RepID=UPI000485BB61 -------ELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVAKQNVAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSTTSRA -QLTEWLVGCKTGANRLRAGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GTPSAAQIETVFARIGHMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. C1 TaxID=1479019 RepID=UPI0008D9C6B4 -----EPDWTAIERRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKVLAVAAVLARVD -AGRETLGRIVTYGPGDLLSYAPVTRKALEAGMSVADLCAATLVWSDNAAANLLLADLGGP -AALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRILLGTTLSPASRD -RLEAWMVACETGRKRLRAGLPPDWSAGDKTGSGDNGTVNDVAILRPPGRAPILVAVYVTG -STASPDTCAAAYAEIARLIA--- ->[subseq from] UPI000FE182C0 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FE182C0 ----YNSAFSQLESDYGAKLGVYAFDTETNKEV-AYRADDRFAYCSTFKALAAGAVLKQDS ---LEQLKQLVKYKKEDVLSYAPIAKDNVDKGMTIEEICSAAIRFSDNTAANLLLNHIGGP -KGFKSALNQLGDSVTQPVHIEPELNEGIPGDIGDTSTPRQLATDLQAYTTGNILTEDKKK -ILIDWMAGNTTGNTLIRAGAPKSWIVADKSGTGPYGRRNDIAIVMPPNKKPIIIAILSTH -DTKEAKYDDKLIAKASKIIFDSf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_042 TaxID=2175626 RepID=A0A2W1NUV3_9MICO ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSGHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRAEPDLNQAVPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRGPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium haemophilum TaxID=29311 RepID=UPI0012E007ED ----LSQSFAALERKYDARLGVYALSTTTATTI-AYRADERFAFCSTFKAPLAAAVLQGHP ---VAYLDTVISYRQDAIHAASPITEQHVETGMTIGQLCDAATRYSDNTAANLLLNDIGGP -AGFTTYLRSLGDTVSRLDQAEPEMNRNPPGDERDTTTPRAVGGVLQKLILGDALTSDKRA -MLTDWMVRNTTGNKRIRAGFPADWKIADRTGSGDYGRANAIAVVWSPAGAPSVVAIMSDR -NGYEAQPSDALIADAAAGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDD50FA -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAAGERNGIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root483D2 TaxID=1736545 RepID=A0A0Q7PL10_9RHIZ -----QEAALLIEERLDARVGYAIYNSGNGESW-LFNADERFPMVSTFKALACAALLAKAD -TGEKSLDNTIEINDSDLVTYAPVTKDWVGREVSLGDLCDATTRTSDNPAANKILENIGGP -EGFTAFMRTIGDNITRLDRWETELNEGTPGDERDTTTPRAIALSLQNLLLGDSLSRNSRE -QLAAWLKGNEVGDPLLRAGIPKNWQIADRTGAGGHGTRGIIAVIWPPEKAPLVAAIYITE -TDATMDERNTAISQMGQALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A0A3XW37_BRAJP -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPEAMAGNLKRLVVGEALSPASRT -QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVAWPKNKVPILIAAYTQG -GTPNAAQIEAAFARVGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD133 TaxID=1053233 RepID=R8E0T4_BACCE ------------------------MDTDTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDSGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREVGDTVTNPERFEPELNEVPPGDVRDTSTPKALATSLQAFTLGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI0013DD2CED ---DAERRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPDLNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115F0F9A ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALRPDG------------ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=A0A087EKY6_DELAC --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSLLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. 150FB TaxID=1576605 RepID=A0A0C2B7T8_9ACTN ---RAEKQLAALEARFGGRLGVYALDTGTGREV-RHRADERFLLCSTHKALAVAAILRARR -LRPGLLDTVIHYDSSELVSNSPVTGEHLDEGMTVAALCEAAITVSDNTAANLLVRVLGGP -RAVTRFVSTLGDPVTRVDRTEPELNEA--TGDLDTTTPGHIGADLRALTLGQALDPAGRD -LLVGWLTANTTGGEEIRAGVPAGWRVADKTGSGNNGESNDIAVVYPPGRAPLILAVYTAP -TDPDSTAGSPTIAQAARIVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR8_STEMA ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATALSQAE -RAPALLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATVITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -SAISNEQRAGVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. LD6 TaxID=2547393 RepID=UPI0010607175 ------DDFTALEHDAGGRLGVFAIDTATGKQV-GHRADERFPVCSTFKLILVGAVLTRGV -TEPALMQQRLRYSSNDVVTYSPVTGPHAGDGMTVAELCAATLEYSDNTAANVLVKMLGGP -AAITSFARSIGNATFRLDRLETELDTSIPGDPRDTATPASMAHSTQSLALGDALPAPQRQ -QLKDWLIGCKTGQHRVRAGVPATWTAGDKTGTGEYGTTNDLAVLWPDASGPIVLGVYYTQ -STQNAQPRDDVIAAAARIAVR-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_026 TaxID=2175621 RepID=A0A2W1RB77_9MICO ----TARVFAALEQRYDARLGVVAVDTGNGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGVGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRAADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR -ADPDAEPSDALVAAATRAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Inquilinus limosus TaxID=171674 RepID=A0A211ZLP4_9PROT ----AAARLAELERAHGGRLGVAALNLATGARI-GHRADERFLLCSTFKALAAAFVLARVD -RKQERLDRRIVIARKDLVGKSVLEPRVGGAGVTVAELCDAAVTDSDNTAGNLLLASFGGP -AGLTGFLRSLGDEVSRLDRTEPTLNAAAPGDPRDTTTPAAVLETLRKLVFGDALSAASRH -RLAAWLITNKTGDTRLRAGFPAGWLVGDKTGTGGEGSTNDIAVAWPTDRGPVLVAAYCEL -PSLSFAQRNPVVAEIGRIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salipaludibacillus agaradhaerens TaxID=76935 RepID=UPI000998D25E ---TVEDTFSQLEGEYDARLGVYALDTGTGKTV-TYRSDERFIYASTHKPLSVGVLLQQKS ---IADLDELITYSSEDLVNYNPITENHIDSGLTLKELSDASIRYSDNTAANLIFHEIGGP -EGFKEGLRAIGDNVTEPERIEPELNDVEPGDIQDTSTPEALAKSLQQFTLGDALADDKQA -LLIDWLKRNTTGDALIRAGVPEGWEVGDKTGSGSYGTRNDIGIIWPPDRDPIILSVLTSK -EERDAEHDDALIARATEEVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=UPI000D0AB075 ------ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP ---IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP -SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA -LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR -PGFRTPPSERLIAEAAERIV--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_011 TaxID=2175643 RepID=A0A2W0DWD6_9MICO ----TARIFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRAIGDRTTSVDRVEPDLNEATPGDRRDTTTPERFAADLGTVLLGDALDAADRR -VLRAAMLRNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR -ADPGAEPSDALVAATARAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. HMWF018 TaxID=2056855 RepID=A0A2R7P7Y3_9BURK ---AWNDALASIERAAQGRLGVAMLDTGSGLAL-GWQQDERFALASTFKLVLAGWMLALVD -QGKERLDARVHYPATDVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDEVTRLDRTEPALNEAAVGDPRDTTTPLAMQQTMQKLVLGNALSPISRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTAGSGTANDIGVLWPQDGAPVLVTCYLTR -SKASPEPRDAAIAQVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID2999 TaxID=2690258 RepID=UPI001368737B ----LRSELAALEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPADILSNSEQTKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRE -QLVGWLRGNTTSGRRFGAGLPSGWVLADKTGTGSYATANDLGVAWTGKGTPLLLSVLSTR -PAPDAAVDEALIEETARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=UPI00034E6FFF --qAFRTELARIEKSVGGRLGVAVLEVESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVRYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. CYP1-5 TaxID=2604572 RepID=A0A5D3FMW9_9ACTN ---AVAAKLRAVEKARGVRVGAYAVDTGTGRFV-SYRGGERFPFASSFKAMACGAVLRKAD -SDRTLMDRVIRYKKSDLADFSPVTKKHVGTGMTVADLCHATITQSDNTAGNLVLKLIGGP -PGLTAFFRSLGDTSSRSDRREPGLNHWRPGEPRDTATPAAWAGDLRALTVGDALAQPDRA -RLIGWLKATVTGDKRIRAGLPKSWTVGDKTGTAGYGHAVDIAITWPPNRAPLVMAVMTTR -PGADDAADEKAVAETARILAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ST1020 TaxID=1848901 RepID=UPI000DD841ED --------FAGLEEEYAARLGVFAHDTATGRTL-THRADERFPMCSVFKAPAAAAVLRDGV -----DPAKRIHYTQQELTDYAPVTEKHLDTGMTVEELCAAAVSHSDNAAANFLLRELGGP -TAITRFARSLGDPVTRLDRWEPDLNSAEPWRTTDTTTPHAIARTYAKFLLGDVLRPADRT -RLTSWMVANSTNVTRFRAGLPADWILADKTGGASYGVANDVGVVWPPGRAPLVIAVLTTT -YAAEGPSKNELVAKAAARVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus thuringiensis YBT-1518 TaxID=529122 RepID=V5M6J9_BACTU -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTS--LAVGALLRKNS ---LEALDQRITYTHEELSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREVGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIADATKVVLN-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000D0E1101 -----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPSLLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPALRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Root1304 TaxID=1736450 RepID=A0A0T1SBM5_9ACTN ------ARLRELEQRHSARLGVYAHDVRTGRTI-AYRAGERFPMCSVFKTLAVAAVLRDLD -HDGTFLARRIRYTAAEVRRWSPVTGENLACGMTVSELCDATLRFSDNTAANLLLRELGGP -TAVTRFARSVGDPTTRLDRWEPELNSAEPWRETDTTTPRAIGRTYGRLLLGGALAPRDRE -RLTGWMLGNTTSVERFRKGLPADWALADKTGGGRYGSNNDAGVTWPPDGGPIVLAVLTTR -DAEDAAPVDALVAETASVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Leminorella richardii TaxID=158841 RepID=A4FRA8_9GAMM --dALQQKLADLEKSTGGRLGVALINTADNSQI-VYRGDERFAMCSTSKVMAAAAVLKQSE -TDSRVLSKKRCDYKSRSDQLEPNCQEALGAGMTLAEMSAATLQYSDNTAMNKILTHLGGP -EKVTAFARSIGDTTYRLDRTEPALNSALPGDPRDTTTPLAMAKSLRSLTLDNALGETQRA -QLVEWMKGNTTGDASIRAGLPKNWIVGDKTGSGDYGTTNDIAVIWPENRAPLILVTYFTQ -PQQNAKARRDVLASAAKIVTE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. LLH-Irr-34 TaxID=1564883 RepID=A0A097SRR5_9ACTN ------VKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRI------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCBAU 15635 TaxID=1128180 RepID=UPI0004BB5E0E ------PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYGKPDLLDYAPTAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D8FF5F -----ASDFAALEKACAGRLGVTLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPSLLDRRVPVREADLLSHAPVSRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPVAMATTLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWSVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Enterobacter TaxID=2608935 RepID=A0A3N2EKH4_9ENTR ---ALEAVVKQEEQALNARIGVAAIDMATGKKV-SYRGNERFPLNSTHKALSCAALLSEVD -KGRLALTSSTRFSQSRLVDYSPVTEKFVEPAITWRHLCSAAVSDSDNTAANLVVERVGGP -AAVTRFLRTTGDNVTRLDRDEPELNSAIPGDERDTTTPIAVSQTLQKLALGEALKLPSRR -QLIQWMRDDKVADALLRSVLPAGWSIADKTGAGANGSRSIIAVVWPLTGKPMIVAIYITE -TEASLTQSNEAIARLGKALF--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDDAC8F -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVDGSPATKAHVRDGMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTAAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAADERNGIVAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI000D226BDA ---TLAQRLAGIERRTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFILTAAVLQRVD -RGELSLQQRLPVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A329XMX7_ECOLX -----------------------------------------FPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHHMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. M3 TaxID=295102 RepID=UPI00100F07EB -----EQAFGELEQKFDARVGVYAVDTGSGLTV-THRPDERFAYASTCKALLAGALLKTYT ---LPQLDRRVRYGPGDLVANSPVTEQHVDTGLTVRELCDAAVRHSDNTAANLLFQELGGP -GGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALATDLRAYALGGALGADARA -VLNDWLERNTTGDALIRASAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVFSRR -DARDAEPQDALVAGAARVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Actinotalea ferrariae CF5-4 TaxID=948458 RepID=A0A021VVK2_9CELL -------ALADLEASFDARLGVVAVDTGSGRRV-EHRADERFAYASTIKALLAAAVLDSTT ---DEELDEVIRFTSSDLVTYSPVTEDRVGEGMTRRELADAAVRFSDNTAANLLLEDLGGP -EALARALRAVGDDVTLPVRTEPALNEAVPGDDRDTSTPRALAASLRAFAVDDALSATDRQ -VLNGWLQGNTTGDELIRAGVPAGWLVGDKTGSGGYGTRNDIAVITPPGRPPIVLAVLSDK -GEVDAESDPALIAAATRVALE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=[Pseudomonas] geniculata TaxID=86188 RepID=UPI000D19F265 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPGSRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces cinereoruber TaxID=67260 RepID=A0A5J6IJ10_9ACTN ----HRREFRALEDAFDARLGVYAIDTGTGREV-AYRDGERFPYASTFKALAAGAVLRKES ---LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELGGP -KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SDREAKPDNRLIARAASVVA--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Marinobacter TaxID=83889 RepID=A0A653SMQ5_9ALTE ----LLEAVKTVEQRLDARVGIALYDSGTGESW-DYHGDDHFPITSTFKTLACAALLAKVD -NGTVDLDRRVIFSKDDLVTYSPVTETRAEEEMSLRELCEATMATSDNTAANLVLGAIEGP -DGVTAYARDLGDTVTRLDRTETSLNEATPGDLRDTTSPKAMVANLRKLVLGDALSKGSRD -TLVTWLKGNRVSDNLLRAAIPPDWTIGDRSGAGGHGSRSITAVLWPPHRPPLVTAIYITQ -TDASFDERNGAIRDLGGAIVKHf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Z0DK01_STEMA ----AAADFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSVLAATVLNQAE -RTPALLDRRVPVHEADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0004CB14E2 ----TDRAFAELERTFDARLGVYAVDTGDGRTI-AHRPDERFAYASTCKALLSGAVLAKKT ---LPQMERLVRYGQEEIISNSPITEKHVATGMTLRELCDATIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRVTRCDRYEVALSDATPGDLRDTSTPRALAADLRAYTLGSALPAEKRA -VLIDWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVWPSGGAPIALAVLSRR -DIKNAETDDALIAGAAKVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A1J1CUK5_CLOBO ----YNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFDHIGGP -SGFKSALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKK -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQASKIVFDSf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB79_STEMA -----ATDFAALEKACAGRLGVSLLDTASGRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RARPLLDRRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAEGDPRDTTTPAAIAMTLQRVVLGEVLRPASRQ -QLADWLIDNETGDECLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRAMVLAQVGRIA---- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium TaxID=374 RepID=A0A2U8P3Y7_9BRAD ------PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYGKPDLLDYAPTAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter capsici AZ78 TaxID=1444315 RepID=A0A125MNF3_9GAMM ----WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE -LGKVTLSQQVPITAVDMIAHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP -QGLTRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ -QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPLLIVSYLAT -AKLDGAGRDAVLASLARIVSK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-525 TaxID=1463861 RepID=UPI00068B44D5 ---DVTAGLRSLEEQHTARVGVFAHHLGTKKTV-VHRADELFPMCSVFKTLAAAAVLRDLD -RHGEVLYKVVHYTEADLVDGSDQTRAHLADGMTVEQLADVAVRYSDNGAGNLILRELGGP -TAVTRFARSLGDRVTRLDRWETELNSAEPDRITDTTSPRAIAGLYGKLVLGDALRRPDRD -RLTAWLLNNTTSAARFRAGLPATWTIADKTGSGDYGTANDVGIAWTESGDPVVLAVLTTK -PTPDAPYDNQLVANTAELVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI0004C7AA60 ---NLAPRLRELEQLHSARLGVFAHDVRTGRTV-AYRADERFPMCSLFKTVAVAAVLRDLD -HDGAFLARRIHYTKAYVERYSPKTEENLAHGMTVAELCDATLRYSDNAAANLLLRELGGP -TAVTRFARSIGDTTTRLDRWEPELNSGEPWRETDTSSPRAIGRTYGRLVLGDALAPRDRE -RLTAWMLANTTSGERFRKGLPADWLLADKTGGGRYGGNNDAGVTWPPDGGPIVLAVMTTR -FEEDAAPVNALVADAAALVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Devosia limi DSM 17137 TaxID=1121477 RepID=A0A0F5LSE2_9RHIZ ---EFSQRIAELEARGGGRLGVCVIDTATGRSV-AHRGDERFPFCSTYKLLAATFLLKRVE -AGQEQLDRRIRYGVADLVGAAPYTGKYAGGSVSLQRLAEAAMTQSDGTAANLIVETFGGP -AELTRYARTLGDAVTRVDRYEPELAEAVPGDPRDTTSPNAMAENVRKVVMGEALQQAGTA -QMVAWLMANRTGDERLRAGTPDDWIIGDKTGSSRNGATNDIGFMQPPGRSPLIVAAYYAE -SKLNSAGRSAVLADVARVIVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf361 TaxID=1736352 RepID=UPI0006FA2A3B ----AEPDWAAIEHRLGGRLGIAAAS-A-DRVLaAYRADARFPMCSTFKALAVAAVLARVD -AGRETLDRVVSYGAGDLLSYAPVTRKALEAGMSVADLCAATLIWSDNTAANLLLADLGGP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSTDSRA -RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTQ -STASPDTCAAAYAEIGRLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas aquatica DA1877 TaxID=1457173 RepID=A0A014MLP1_9BURK ----WSQAMAQIEQDAQGHLGVAMLDTGSGMAL-GWRQDERFAMCSTFKLPLAAWVLALVD -QGRERLDARVQYSEAELVEYSPVSGPKAGAGLTVGELCSATVSLSDNSAANVLLARHGGP -AALTAWLRSQGDFITRLDRNEPSLNEAAVGDERDTTTPLAMLHTMQRLVLGTALSPSSRA -TLQRWLIETSTGDQRLRAGAP-GWKVGDKTGTSGSGTANDIGVLWPPGGAPVLVTCYLTQ -STARPEQRDAAIAQVARAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces fulvoviolaceus TaxID=285535 RepID=UPI000694AC09 ------TGLRKLEARHGARLGVFAHNLATERFV-SHRADELFPMCSVFKTLAAAAVLRDLD -RHGEFLARRIHYTEADLPEGSDKTREHLADGMTVAELADVAITYSDNGAANLLLRELGGP -TAITRFCRSLGDPVTRLDRWETALNSAEPWRITDTTSPRAIGRTYGRLVLGDALGRRDRG -LLTHWLLNNTTSSTRFRAGLPKAWTVADKTGGGSYGTNNNVGIAWTEDGAPIVLAVLTTK -PDQDAARDDELVADTAALIAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sophorae TaxID=1300294 RepID=UPI000BA43859 -------KIRRIEAKSGGRLGVSCRISGTTAQF-GYRQGELFPMCSTFKALAAAFILHRVD -GGIEQLDRSIKIPHDAVIANSPTTKKHAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP -AQLTAYLRSIGDKVTRLDRIEPELNESLPGDARDTTSPLAMTGNFERLTIGNSLSEKGRV -QLVDWLVANKTGDERIRAALPKGWTCGDKTGTGAHGSTNDAAVIWPASGNPILMSVYLTG -TKQSLAKRNAVIAAVSHALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea vagans TaxID=470934 RepID=UPI00066019C1 ------AVAQQEEQALKARIGIAVIDTDAESVA-SYRGNERFPLNSTHKALLCGALLSAQD -KGKLRLTERTQFDRTALVTYSPVTEKFIAPAMSWGQLCEAAIAYSDNTAANLLARKLGGP -VAVTRFFAELGDKVTRLDRFEPELNSAVPGDMRDTTTPLAVSETLQKLTLGPALTPASRA -QLLQWMRDDKVADALLRSVLPTGWSIADKTGAGEYGSRSIISVVWPENGKPLIIAIYITQ -TEATLAQSNAAIARIGKAIF--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00106F8EA0 ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISNEQRAGVLAQVGRIA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Devosia limi DSM 17137 TaxID=1121477 RepID=A0A1M5E9U6_9RHIZ ---EFSQRIAELEARGGGRLGVCVIDTATGRSV-AHRGDERFPFCSTYKLLAATFLLKRVE -AGQEQLDRRIRYGVADLVGAAPYTGKYAGGSVSLQRLAEAAMTQSDGTAANLIVETFGGP -AELTRYARTLGDAVTRVDRYEPELAEAVPGDPRDTTSPNAMAENVRKVVMGEALQQAGTA -QMVAWLMANRTGDERLRAGTPDDWIIGDKTGSSRNGATNDIGFMQPPGRSPLIVAAYYAE -SKLNSAGRSAVLADVARVIVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis lexingtonensis TaxID=218822 RepID=UPI000A3955F7 -------DFAPLEREFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSAGAVLQRTS ---MEGLAKVLPYTRADVQPNSPVGEKHVGTGLSLRDAIDAALRYSDNTAANLLFRELGGP -AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAADLRAFALGTVLPAAQRT -FYTDTMRANRTGDAVIRAGTPAGWTVADKTGTGEYATRNDIAVVWPPGRAPIVLAVMSDR -KTENAEHDDRLLAQAAKLTLDAy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces avicenniae TaxID=500153 RepID=UPI00069B3FE1 ----TGRAFRALEQEFDARLGVYALDTGTGREV-AHGADDRFAYASTFKALAVGAVLRER- --GTEGLAEVVTYTEADLVANSPVTENFVDTGMSLRELCAATLWYSDNTAANLLLDALGGP -DGLEAVLRELGDDVTEMDRYEPDLSDAVPGDIRDTSTPRAMADGLRAFLLGDTLERDERR -LLRRWMTTNTTGETLVAAGVPGTWDVADKSGTAGYGGRNDIAVLWPDDGDPIVLAVMSSR -DREGAERDDALIAEAAAVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. CB01950 TaxID=1703930 RepID=A0A1Q5F7D0_9ACTN -----AESFRWLEQHFGARLGVYVLDTGSGREV-AYRADERFAFASTFKALAAGALLRRAS ---DADLDKVVTYRQEDVLTWAPVTSEHVATGMTVRDLLAASLDYSDNTAANLVTDQLGGP -AALQQALRELGDPTTEVSRTEPGLNSATPGDTRDTSTPRALAADLRRYVLDDVLPAARRQ -LLTELMVANTTGGPYIRAGVPAGWKVGDRTGNAAYGTRNDIAVLWPDGGAPVVVAVLSDR -PRQDAASDDALIAQATGAAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519HFF2_9BURK ----LREALQHIETTARGRLGVHIIDTANGREH-GWRSDERFLMLSSFKLLASAFVLDRVD -RGVEKLERRIRYRPQDLVPWSPVTERHVGGELSLAQLCEATITTSDNTAANLILASYGGP -AALTAYAWRLGDAVTRLDRTEPELNRAASGEPLDTTTPRAMAHTLNKLLLGDALKPSSRE -LLLNWLLANTTGGKRLRAGVPAGWRIGEKTGTAGD-DANDIGIALPPQRAPIIVTAYLAE -SRTDAATREAALASVGGLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Desertihabitans aurantiacus TaxID=2282477 RepID=UPI000DF75F6D -------AFAELEARWDARLGVFAVDTGSGRVV-EHRADERFAYASTHKALSAAAVLEQTT ---DEELDRLVRFDADDLVEYSPVTEERLAEGMSLRELADAAVRYSDNTAGNLLLDELGGP -AGFDAALEEVGDLVTQVDRLEPELNTAVPGDPRDTSTPRALATSLRAYAVEEALPAGDRE -VLNDWLQRNTTGDALVRAGVPGGWLVGDKTGTAGYGTRNDIAVVHPPGRAPLVLAVLSSR -DEVDAEHDDALVAEATRVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aureoverticillatus TaxID=66871 RepID=UPI0013DB6236 -----HRQLAALERKFDARLGVYALDTGTGAVI-AHRADERFAFCSAFKALAAAAVLDGNP ---LSHLDDRVRYGKADLMKHAPITSRHVETGMTIRQLCDAAVRFSDGTAGNLLLRDIGGP -DRLTAYARGLGDKVTRMDRFEPAITEATPGDPRDTSSPRAFGSTYREIVLGDALPKSKRA -FLRDLLERNATGAKRIRAGLPRGWTVADKTGTGNHGTLNDIAVVWPPKSAPLLIAIMSSK -AEQDAPYDEALLAEAAAYVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinopolyspora mortivallis TaxID=33906 RepID=A0A2T0GT82_9ACTN --nTVRAEFTRLEQRFGARLGVHALDTGSGEIV-THRADERWAFCSTMKTFTAAAVLRRNT ---VEDLDRRITYTRADLVPYSPVTERHVDSGMTLREVLRAALRVSDNTAQNLLLRELGGP -EGLQRELRELGDTTSHVDRYEPELNEAEPGDVRDTSTPRALAANLREVVLGDALAPEKRK -ILRGAMRNPPLTEELVQAGMPEGWEIEDKSGAGKYATRNDIAVLYPPERDPIVLVVMTSK -SDEDAEYDDALVAEAARTTLD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D91D1A -----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLVATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium salinisoli TaxID=1899321 RepID=A0A368K169_9RHIZ -----EGQLAELERRHGGRIGVAVLDLATGQRL-MHRADERFLMCSTFKALTAGFILARVD -QGEEQLDRRIVFSKKDIVVGSPATQERIGGTMSVAELCQATLTLSDNAAANLLLASFGGP -AGLTGFLRSIGDEITRLDRFETDLNHETPGDLRDTTTPAAMLETLRKLLFGNVLSRSSRA -QLAAWMIMNKTGDAKLRAGFPDDWTIADKTGGNGFGNSNDVAIAWSPDRGAVMITAYCEI -PSVSEKVRAAVLAEIGRIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix deserti TaxID=2593674 RepID=UPI00131C7E29 ---AANDHLVELERKFDARPGVYALATGTGTTI-AHRADERFAFCSTFKTLAAAAVLHRNP ---LSHLDTTIRYTADDLMKSSAITGRHVATGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP -AQLTAYARHLGDTVTRMDRMEPMITEATPGDPRDTTSPRAMGVDHHKIVLGDALPPDKRA -FLRDLLERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPPGSAPLVISIMSSK -ATKDADYNQALIAEAAGYVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071B9A96 --qTLAQRLAGIERGTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELSLQQRMPIRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTFGDAQTRSDRHEPEMNRFAADDPRDTTTPAAMAATLRTLLLGDVLRPVSRQ -RLSEWMIDNRTGDACLRAGLPRGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDDAARDAALKAVAVVV---- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. JHL-3 TaxID=1276755 RepID=UPI0004B6A277 ---QWSDALAGIERAAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYPVAEVVAYSPVSSPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -AGFTAFVRSLGDGATRLDRTEPTLNEAARGDPRDTTTPLAMLQTMRKLVLGDALTPASRT -WLQRWLVQTSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPSGAPVLVTCYLTR -STAQPEQRDVAIAQVARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces novaecaesareae TaxID=68244 RepID=UPI000D11B440 ---DLHRRLADLEQQHSARLGVFARNLTTDRTI-RYRAGELFPICSVFKTVAVAAVLRDLD -HDGEYLARRIRYTQADIDRGAPVTGKNLAGGMTVAELCAAAIDHSDNTAANLLLRDLGGP -TAVTRFCRSIGDRVTRLDRWEPELNSAEPDRTTDTTSPRAIARTYGRLALGHALPPAKRE -RLTAWMRGNTTSTHRFREGLPQDWALADKTGTGEYGTTNDVGIAWTPTGAPVLLAVLTTK -PAPAAPKDEPLVARTAALL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Sinorhizobium saheli TaxID=36856 RepID=A0A178YIJ4_SINSA --qAAAARLDALERRHPGRICVSILEVASGKRV-EHRADERILMCSTFKALAAALVLARVD -KGEERLDRRIKFSKNDLVAGSAATETHAGGAMTMAELCDAAVTRSDNTAGNLLLASFGGP -AALTAFFRSLGDDVSRLDRIETDLNYDGPDDIRDTTTAAAMLENLRRLLFTDALSPSSRS -RLAAWLITNKTGDSRLRAGVPKNWLVGDKTGTNGHGIANDIAVLWRPDGAPIIVTAYCEI -PSISADERNAVIAEIGRIA---- ->[subseq from] Beta-lactamase L2 n=1 Tax=Xanthomonas translucens pv. phlei TaxID=487906 RepID=A0A0K2ZS65_XANCT --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLPIRAADMLSHAPVTERDVGGTLSVAELCRATLLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDALQPASRQ -QLGAWMIDNRTGDACLRAGLPPGWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDDAARDAALKAVAVAV---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000DAA34EF -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRVGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8IJR0_STEMA -----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Nocardia brasiliensis ATCC 700358 TaxID=1133849 RepID=K0EN23_9NOCA ------AELTALEQQYDAQLGLFAVDTGSGKTL-TNRADQRMPFLSTFKGLAAGALLKAHP -LATGYFDKVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP -QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERD -QLTKWLKANTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVIAIQTRK -STTAAEPSNDLVAAATKLVVEK- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis vancoresmycina DSM 44592 TaxID=1292037 RepID=R1GF45_9PSEU ------PDFAPLERDFDARLGVYAVDTGSGREL-AHRADERFGYASTHKAFSAAAVLQRTG ---LDGLAKTLTYTRADLQPNSPVTEKRVGTGISLRDAMDAALRYSDNTAANLLFRELGGP -AGLAGALRAVGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFTLGSALPPDKRA -VLTDMMRANTTGAALIRAGAPAGWAVADKTGTGSYATRNDIAVVWPPGRAPIVLVVMSSR -QGKDAGHDDRLLAQAAKLALDAf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0UDS6_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRS-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDARVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDPVSRSDRLEPELNTFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISNEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura pelletieri DSM 43383 TaxID=1120940 RepID=A0A495QJ11_9ACTN ---DVTRRLLQLEKARDVRVGAYAIDTGTGQVL-AHRADERFPFASSFKVMACAAVLRKAR -RDPGLMDRVIRYGRNDLSAFSPETEKHVGTGMTVAELCRATITRSDNTAANLLLKQIGGP -QGLTAFFRSLGDTVSRSDRVEPGLNRWRPGELRDTTTPAPWARNLQALTVGDALVPADRA -RLVAWMKATVTGGERIRAGLPGGWTVGDKTGTAGHGNANDIAVVWPPSGAPLILAVLITR -PDADAEADDKAVAATAGILA--- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. M10 TaxID=412968 RepID=UPI0006485E42 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTQDDVEQGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP -AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TEQDAVRDDALVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium ottawaense TaxID=931866 RepID=UPI000BEACA61 ------PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYGKPDLLDYAPAAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009A178E9 ----AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANGRFPLCSTSKTMAIGAVLRDLD -HDGTFLSKVIHYTQQDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDKADRT -RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR -PEPDAEADDAVIAETAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Clostridium kluyveri TaxID=1534 RepID=B9E548_CLOK1 ----YNSAFSQLESDYGAKLGVYAFDTETNKEV-AYRADDRFAYCSTFKALAAGAVLKQDS ---LEQLKQLVKYKKEDVLSYAPIAKDNVDKGMTIEEICSAAIRFSDNTAANLLLNHIGGP -KGFKSALNQLGDSVTQPVHIEPELNEGIPGDIGDTSTPRQLATDLQAYTTGNILTEDKKK -ILIDWMAGNTTGNTLIRAGAPKSWIVADKSGTGPYGRRNDIAIVMPPNKKPIIIAILSTH -DTKEAKYDDKLIAKASKIIFDSf ->[subseq from] Beta-lactamase n=1 Tax=Gordonia araii NBRC 100433 TaxID=1073574 RepID=G7H1F6_9ACTN ---STTGRIAALERRHNARIGVFAADLGSERTV-AHRADESFAMCSTFKTYAAARVLQLVE -RGTLSLDTGVFVDAAEIVENSPVTQRHASSTMTVSQLCEAALQQSDNTAGNLLLRAIDGP -QGVTAFARSIGDGRTRLDRWETALNAAVPGDPRDTSTPSALAGGYRALLAGDALSPASRE -RLDDWMRGNQT--SSMRAGLPDGWTSADKTGAGDYGSTNDVGIAYSPGGGRILLAVMIRS -AAPDAEGFRPLIGEVAGLVV--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013DC06D7 -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVMGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria atacamensis TaxID=531938 RepID=UPI000DC38FE7 ----ISGKLRDLEQQHGARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRRDH --NGALLGKVIRYTQEDVTKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLKELGGP -TAITRFSRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRADAD -QLTRWLLANTTGGNRIRAGLPTAWRWGDKTGTGKYGTTNDVGIAFPPGRSPIVIAVLSTK -SVQDAPADEPLLAKTAELVAGTf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Root55 TaxID=1736554 RepID=UPI000B000E8A ---RTARAFRGLEREFDARLGVYAVDTGSGLSV-THRSDERFAYASTCKALLAGALLDAHP ---LRRLDRRVRYGPGDLVANSPVTEEHVRSGLSVRALCEAAIRFSDNTAANLLFRELGGP -GGLQDALVALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALAADLRAYVLGDVLAPDARA -LLTDWLRRNTTGDTLIRAGTPDGWVVGDKTGTGGYGTRNDIAVVWPPGSAPITIAVLSRR -AAHGAEPQDALVARAAGVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia acaciae TaxID=551276 RepID=UPI000688E260 -----ADEFGGLEREYGARLGVYAVDTGTGREV-AYHADDRFGHASTFKALAAGAILRRVP ---LDGLNKVVRYARSDLKSNSPITQQHVDTGMTLRAAMDAAVRYSDNTAGNLLFRELGGP -GGLTAALRDLGDTVTRSDRFETELNDVSPGDPRDTSTPRALAGSLRAFTVGTALPEDRRA -LLTDMLRANTTGATLIRAGAPAGWQVGDKSGAGGRATRNDIAVVWPPGRAPLVLAVLSDR -PAPDAPYDDKLIARAAAVAFAAf ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA1C69B ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAER-------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Terriglobus roseus TaxID=392734 RepID=A0A1G7F143_9BACT --qRLPQQVAALERASGGRIGVYALDTGNGKFA-GNREDQRFPMCSTFKFLLAAAVLKLVD -DGKQSLDQSLPIPNKPLIGHSPLTEPHAGATMSVAALCNAILNQSDNTAANVLLDAIGGP -PAITAFTRSIGDEFTRLDRNEPDLNSSIDRDPRDTTTPVAMAKNLQRILLGNTLKPASRR -QITEWMENSLTGLERLRKDMPEGWRAADKTGSNGEHTTNDIAILWPIHRPPVIVTCYITQ -CPGPETKRGAMIAEVGRFI---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus PD630 TaxID=543736 RepID=A0A3G9MFC2_RHOOP ----LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP -QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEGAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Hydrogenophaga sp. BPS33 TaxID=2651974 RepID=UPI0013200858 ----LQEALRDIERKAKGRLGVHIIDTSTGLEL-GWRSEERFLMLSSFKLLASALVLDRVD -RGVESLQRRIRFSKEDLVSWSPVTERHVGGHMSLAQLCEATLTTSDNTAANLILASYGGP -AALTAYARRLGDSETRLDRTEPALNRAASGEPLDTTTPRAMANTLRTLLLGKALAPESRD -RLTQWLLANTTGGKRLRAGLPVGWQIGEKTGTAGD-DANDIGIAFPVQRAPIIVTAYLAE -SATDAATRENALASVGRLLT--- ->[subseq from] Beta-lactamase n=2 Tax=Saccharopolyspora TaxID=1835 RepID=A0A1H6ELL8_SACHI -------DLAELERRYDARLGLYAVNVRTGRTL-VNRPDERFALCSTFKTYAVAALLRDHG -LSSGYFDKVIRYTEEELVSNSPETEKHVDTGMTVRALCEATMTVSDNTAANLLLRERGGP -QSIAPFARSIGDPTTRLDRWEAELGTAIPGDERDTSTPAGLAAGYRSLVLGDALAAPERD -QLTKWLLANTTGDECIRAGVPPTWRTGEKTGAGDYGTRNDVGVTWTEDGTPIVIAILTTR -PRPDDEYRNELLADTARAVAAH- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TRM68295 TaxID=2569859 RepID=UPI00124B29D1 ------GELKELERKFDARLGVYAIDTGTGREV-AHRDGERFGYHSTFKALEAGAVLRKYS ---LNGMNKVIKYSSDDLVANSPITEKHVETGMTLSELCDAAVRYSDNTAANLLFDALGGP -KGLESDLRKLGDKVTLMERIEPHLSDWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA -QLTTWLKTNTTGNEVIRAGVPEGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR -GKAEDVHDNKLIAEAASVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 351MFTsu5.1 TaxID=1172180 RepID=UPI000376238F ---DVAARLRALEQRYDARLGVFAHRLSTKRSV-RFRADELFPMCSLFKTLAAAAVLRDLD -RHGEVLARRVHYTEDDLVIGSDQTAAHLAEGMTIAELAEVAITYSDNTAGNLLLRELGGP -TAITRFARSLGDRTTRLDRWEPELNTAEPWRRTDTTSPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLSNTTSVNRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTEDGDPVVLSVLSTL -REPDAVRDDALVADAAAVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus szentirmaii DSM 16338 TaxID=1427518 RepID=W1IQA9_9GAMM --nQITEKLLILEKNANGRLGAVLINTANHSII-AYRGNERFPLCSTSKFMVVSALLKQSE -TSDHLLNQQVHYQQSDLVEYSPITEKHLKNGMTLGELSSATLQYSDNTAMNLILDALGGP -NEITKFARTIGDKHFRLDRKEPELNTAIPNDERDTSTPQSMADSLYHLALGHALALEQRN -QLVEWIKGNTTGATSIRAGVPKNWVVGDKTGRCDYGSTNDIAVIWPENRPPLVLVTYFTQ -PNKNAVARPDILAETARIMIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_051 TaxID=2175640 RepID=UPI000DA86239 ---ATARAFAALERRYDARLGIAAVDTGDGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLAAVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLRGP -DAVERWLRGVGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR -ADPDAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Bradyrhizobium TaxID=2631580 RepID=UPI0004B62E4E ------PELETYERDSGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIAYGKPDLLDYAPAAKQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALSPASRA -LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVVWPKPGTPILIAAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Xenorhabdus sp. GDc328 TaxID=742178 RepID=A0A0M0TCE3_9GAMM ----IIHQLSILEKNANGRLGVVLLDTSDHSII-SYRENERFPLCSTSKLMTVSAILQKNE -TNAHLLNQRVHYQQSDLVEYSPMTEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGS -HEVTRFARTIGDHYFRLDRREPELNTAIPGDDRDTSTPQAMAKSLYNLVLGTALATTQRE -QLTEWIKGNTTGGTSIRAGLPKNWIVGDKTGRCDYGTTNDIAVIWPPDRAPLVLVTYFTQ -PNKEASARPDVLAAATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0R0BDE5_STEMA ----AATDFAALEKACAGRLGVTLLDTASGRRA-GHRQDERFPMCSTFKSVLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNRFAEGDPRDTTTPAAMAGSLQRVVLGPVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLRA -GQISYEQQAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sinuspersici TaxID=501010 RepID=A0A1V3BYY2_9ACTN -----DSEFERLEEEFDVRLGVYALDTGTDRVV-EFQADERFAYCSTFKALAFGAVLDRTP ---VDGLDRVVTFSEADLVFHSPVTRKHVDSGMTLREIGDAALRHSDNTASNLLLEELGGP -EGLEEALRGIGDDVTRVDRVAPEMAEAVPGDVRDTSTPRAMATSLRAFALGDVLPEDGRG -VLVGMMRANTTGDGLIRAGVPKGWTVGDKTGACGYGTRHDIGVLWPPEGAPVVLAVMSSR -DEAGAEYDDALVAQATELAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NBRC 110468 TaxID=1679753 RepID=UPI000D14B8CA ----VTARLRDLEAAHGARLGVFAHNVRTRRTV-RYRADERFPVCSLFKTLAVAAVLRDLP ---EGTLDRRVYWTAADVVENSPVTQEHVADGLTVAELCAAAVQRSDNTAGNLLLREIGGP -AGLTRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTSPAAIGRTYGRLVLGDALAARDRR -RLTDWMLGTVTSANRFRAGLPPTWTVADKTGGGWYGANNDAGVAWTPDGAPVVLVVQLTK -PDREAAYDHDLIVETAKVLAE-- ->[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071E96B9 --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLPVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas maliensis TaxID=1321368 RepID=UPI0003A86D5F ---ALRVRWAEIEGRSGGRLGISLLDTATGQRI-EQRQDERFPLCSTFKFLLVAAVLQRVD -RGELRLDRQVPIRAEDMLSYAPATKPHVGGSLSLAELCQAAMIFSDGVAANLLLTQVGDP -AGLTAFIRTLGDTQTRSDRNEPSMNNFALDDPRDTTTPAAMLGSMRAVLVGDALLPASRK -RLTEWMIDNRTGDDCLRAGFPQGWKVGDKTGNNGTDSRNDIGIVWVPGQAPLLLTTYLNK -ATVDADARDAALKAVAQAVAAWw ->[subseq from] Imipenem-hydrolyzing beta-lactamase n=4 Tax=Enterobacter cloacae complex TaxID=354276 RepID=BLAN_ENTCL ------DEIKNLETDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ -DNRLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEHEKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] Beta-lactamase n=1 Tax=Pararhodospirillum oryzae TaxID=478448 RepID=A0A512HAI3_9PROT -----AATARAVEARLDARVGVFVVDTGGGTTW-AYRADERFPMASTFKALACGALLARIQ -AGEESADTSVPIEAQDLVSYAPVTKTLVGQRVPVLDLCAITLRTSDNTAANKILEHVEGP -AGLTRFVRALGDETTRLDRWETALNEGIPDDPRDTTSPRAMATTLRALVLGPILSEDGRL -RLVRWLESNAVSGSLLRAGVPADWRIADRSGAGGHGTRGLTAVAWPPGRAPLVIAIYLTK -TEAPMADRDAAIADIGRALV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE2118D -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVDGSPATKAHVRDGMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVAAYCEI -PAIAAGERNGIVAEIGCIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WM6368 TaxID=1415554 RepID=A0A0M9XXY7_9ACTN ----VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD -HDGAHLAKRIHYTAQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLILSILSTL -PEPTAPRDNTLIARAAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543DJ04_9PSEU ----------VLERRFGGRIGVHALDTGNGATV-SHRSGERFLMASTAKLPLAAAVLDRAA -TEPALLDRLVRFGPEALLEYAPVTTQNVATGMTVADLCDAALTVSDNTAANLLLELLGGP -AAVTAFARGLGDATTRFDRSEPELNSTGPDDERDTTTPAAIVASIRAVTLGEGLEPAGRE -RLTAWLVANTTGDATIRAGVPAGWVVGDKTGTGEQGERNDVGIVLPPDRAPLVLAVYTDP -DDPDSTAGNATIAEATAIAVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=A0A495RY09_SPHMI ---ETLRRLEEIEARSGGRIGFFVRDTGSRRAI-AHRADERFAMASTFKAPLAAAVLAGGE -AGEFRLDRRIPYTAGDLLEYAPVTKRHVSEGMSIEDLCAAIVELSDNTAANLLLPLVGGP -AGFTRWLRGIGDTETRLDRTEPTLNANTPGDPRDTTTPRAMAATLERLLVSDVLPQAARD -RLTGWMVASPTGRDRLRAGLPVDWRVGDKTGTGMNGAVNVIAILWPPKAAPLIAAIYMDG -SKAPLADLNAAHAALGGLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A2S8IQN7_RHOOP ---SLDATIDALETQYSTRIGVTAVNPATGEIY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIDPGDLVENSPVTAAAVGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDAASRD -QLLEWMRASKTSDKRMRAGLPTGWTAGDKTGGGGFGTANDAGVAWSPDGAPVVLAILTDS -LTQDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis circi TaxID=871959 RepID=UPI000E226E48 ----VQPDFAALEKAFDARLGVYAIDTGDGREV-AYHADERFAYASTHKVFNAAAILHRGD -----DLNRTVTIRQSDLVPNSPITEKHLGEQMPLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAEVRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA -VLVKIMRANTTGANVIRAGVPADWQVADKTGSADYATRNDIAVVWPPNRAPIVLAVLSDH -AKKDAKTDDKLIAQAAAAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDEBCA7 -----EAELAALESRHPGRICVSILDMASGKRI-EHRARERILMCSTFKALAAALVLARVD -RGQEKLDRRIRYTKSDLVDGSPATKAHVRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KTLTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRTGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAADERNGIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. AT1 TaxID=574934 RepID=A0A150UFW0_9BRAD -------ELESYERESGGRIGVYAENLANGKKL-AWRADERFVMCSTFKASLAACVLARVD -HGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVADMCKAIVELSDNTCANLLLARIGGP -AVLTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGEALSPASRT -LLTEWMVNCKTGANRLRGGLPTSWTIGDKTGNNGKDASGDIAVAWPKPETPILITAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MZ03-48 TaxID=2593677 RepID=A0A553ZNQ4_9ACTN -----AHDLRQLEQKFSARLGVYAIDTGTGREV-AYRDGERFPFNSTFKALAAGEVLKQRT ---LSGMNEVVRYSQDDLVPNSPVTEKHVGAGMTLQALCDAAVRYSDNTAANLLFDKLGGP -KGLNAALKKLGDQVTRMERPEPLLSTWDPKSTRDTTTPRALTKDLRAYVLGKVLRPAERT -QLTTWLRTNTTGDTLIRAGVPKSWVVGDKTGMGSYGTRNDIAVLWPAHSSPIVVSILSSH -GAEDATPDDKLIAEAASVVAH-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229RV86_9PSEU ---AARTDFEQLERTFGARIGVYAVDTATGREV-AFRADERFAYASTHKVFTAGGVLQRTP ---LADLDRTVTYSEKDLVSNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPELNDTFPGDQRDTSTPRALAVGLRAFALGTALPEDKRK -VLVDMMRANTTGDENIRAGVP-GWPVADKTGTAGYGTRNDIGVVWPPNRAPIVISVLTDR -TAKDAKIDNKLLAQATAAAVK-- ->[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus nematophila TaxID=628 RepID=N1NRD4_XENNE ---QIIEKLSILEKNANGHLGAVLINTADHSTI-AYRADQRFPLCSTSKLMAVSALLKRSE -TNDHLLNQQAHYQQSDLVEYSPITEKHLKSGMTLGELSAATLQYSDNAAMNLILNQLGGP -HEVTKFARTLGDNSFRLDRKEPELNNVIPGDERDTSTPRAMADDLYHLVLGNALDATQRE -QLITWLKGNTTGAASIRAGVPEGWIVGDKTGRCDYGSTNDIAVIWPVNQPPLILVTYFTQ -PDKEASARPDVLAAAARIMTQH- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD5E19F --hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIGFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRPSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVASYCEI -PTISADERNAVVAEVGRIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. 3P27G6 TaxID=2502215 RepID=UPI0010F56C11 -------KIRRIEAKSGGRLGVACRISGTTVQF-GYRENELFPMCSTFKALMAALVLHRVD -GGIEQLDRAIKVPHDAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLASFGGP -PQLTAYLRSIGDTVTRLDRIEPELNESVPGDVRDTTSPLAMIEDYERLALGDSLSQKGKA -QFVDWLVANKTGDERIRAALPKGWKCGDKTGTGEKGSTNDAAVIWPASGNPILMSVYLTG -TKQNLAKRNATIASVSRVLVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AA4 TaxID=591158 RepID=D9V5K6_9ACTN -----QPDFAALEKAFDARLGVYAIDTGNGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLARTVTIRQSDLVSNSPITEKHVGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRAWAKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSAEYATRNDIAVVWPPNRAPIVLAVLSDR -PRKDAKTDDKLIAQAAAAVVK-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000A2FB291 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A427CII7_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7C9AB --hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVATYCEI -PTISADERNAVVGEVGRIVAE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013DAD9CE ----TAKDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISNEQRAGVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A5B8DS91_9ACTN ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTQADVEQGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP -AAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TEQDAVRDDALVADAARVLAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Azonexus fungiphilus TaxID=146940 RepID=A0A495WIR3_9RHOO ----FGARLAALEAAVGGRLGVFIIDTASGASV-GYRADERFMLLSSFKALAGACVLQRVD -AGRERLDRRIVFDRSVLLPWSPVTEKFADGRMTVGELCAATIATSDNAAANLILDSLGGP -AALTAFLRGSGDDVSRLDRREPELNQPAADPAFDTTTPRAMAATLQRLLLGDVLSPASRR -QLQDWLLACATGERRLKAGLPVGWRIGDKTGSSRS-DANDVGIVWPPGRPPLLVAAYLSG -SPAEPAAREACLAAVGKILAD-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium RIFCSPHIGHO2_12_FULL_41_10 TaxID=1802433 RepID=A0A1G3ZPT0_9BACT ---QTNSSFTELEASSGGHLGVSAINTANNKIV-QYHAEEHFPFQSTFKVMVVSAILKKSM -ADPQLLQQKVTYKKEDLLSWSPITEKHLTDGMTVSELCAAAIIFSDNAAVNLLINKLESP -QAVTAFARSIGDDQFSLEDREGNLNSA-PGDLRDTSTPAAMAKSLQKLALGNILGASQQK -QLVTWMTDCTTGYARIHAGVPIGWIVADKTGSGDYGITNDIGIIWPPNCPPIVIAIYFIQ -NKKDALRRDDVIASATKIILS-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071E993B --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFILTAAVLQRVD -RGELSLQQRLPVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00131FAB70 ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] BKC/GPC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Shinella kummerowiae TaxID=417745 RepID=UPI001323D018 ---TLEKRLAELEARHEGRLGVAILNFATGARL-GHRTDERFLMCSTFKALLAGHILARVD -REEEALDRRIVVKKSDLVDWAPVVEKRIGGDISIAELCEATITLSDNAAANLLLASSGGP -KAVTEFLRGFGDDITRLDRTEPTLNYDTPDDERDTTTPVAMIETLRKLIFGDVLSPRSKA -QLAAWLVMNKTGDTRLRAGFPADWMTGDKTGTNGAGNANDVAIAWSPNRGAIIVSAFVEM -PGISGDERNAVIAEVGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4U9P4P3_STEMA ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Scopulibacillus darangshiensis TaxID=442528 RepID=A0A4R2NKL5_9BACL -----TEDFAKLEDKFDARLGIFALDTGTNQTV-TYRSDERFAYASTLKALTVGALLQQKS ---LADLNQTITYTQDDLVNYNPITKKHVDTGMTLKELCDAALRYSDNTAENLILKQLGGP -SSLKKSLRKIGDNVTNPENFEPKLNEVKPGETHDTSTPKALAESLKAFTIGDALPTKKRS -LLVDWLKRSTTGDTLIRAGVPKGWEVGDKSGGSSYGIRNDIAVIWPPKGDPIVLAILSNR -DKKDKGYNDKLIAQATKEVIN-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B5KLI1_STEMA ----AAADFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVMMGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D94C73 ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MMG1121 TaxID=1415544 RepID=A0A0M8V1S8_9ACTN ------GELSELEQRHGARLGVFARNIRTGRTV-SYRAGERFAMCSTFKAFAAAAVLRDHG --DCAPLDKVIPYPPHDILSNSPRTAEHVDTGMTVGDLCAAAIQYSDNTAGNLLLRQLGGP -AGLTRFFRSLGDGVSRLDRWETDLSSAIPADPRDTTTPEALGRSFERLALGRALARADRA -RFVGWLKGNTTSAARFGAGLPHDWVLADKTGTGDYGTANDVGVAWTTRGTPLLLTVLSAK -KAQDAPADEALVAEAARILA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CWH03 TaxID=2705029 RepID=A0A6A0ANY0_9ACTN -------RLSELERTHSARLGVFARNTRTGRTV-AHRADELFPMCSVFKTPAVAAVLRDLD -RNGEFLGKRIHYTEQDTEEYAVITGRNLANGMTVEELCDAAIRYSDNAAANLLLRELGGP -SAVTGFCRSLGDDVTRLDRWEPGLNSAEPWRAEDTTDPRHIAETYSRLVLGDALAGPDRQ -RLTGWLLNNTTGTLRLRAGLPDDWTLGDKTGAGAYGTNNDVGIAWTPDGSPVVLAVLTTK -PQPDAAPDNELVARTAQLLAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066B1B60 ------GDFAALEKACAGRLGVTLLDTASSRRV-GHREDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Lysobacter capsici TaxID=435897 RepID=UPI00062749C6 ----WRTRLRDLEKHSGGRLGVAVLDTGNGERM-LWRENERFRMCSTFKYLLAAAILRQVE -LGKVALSQQVPITAADMISHAPFTQPLVGRSASVAQLCEATVTLSDNPAANLLYPLVGGP -QGLTRFLREIGDGVTRTDRTEPTLNSGAPDDPRDTSTPSAQIATMQRLLLGDALKESSRQ -QLIAWLVANKTGDKRLRAGLPAGVRVGDKTGSGDD-ATNDVAIVWPPGRAPLLIVSNLAT -AKLDGAGRDAVLASLARIASEHf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WM6368 TaxID=1415554 RepID=UPI0006ADB087 ----VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD -HDGAHLAKRIHYTAQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLILSILSTL -PEPTAPRDNTLIARAAKLLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HC44 TaxID=2711217 RepID=UPI0013EBF68D ----FTGELKELERKFDARLGVYAVDTGTGREV-AYRDGERFGYHSTFKALEAGAVLRKYS ---LNGMNKVIKYSSDDLVANSPITEKHVESGMTLRELCDAAVRYSDNTAANLLFDALGGP -KGLEADLRKLGDKVTLMERIEPHLSNWVPGETRDTTTPRALAKDLRAYVLGDVLRKRERA -QLATWLKTNTTGNEVIRAGVPEGWVVGDKTGTGGYGARNDIAVVWPPDSAPIVMAVLTNR -GKAEDVHDNKLLAEAASVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. NS-7484 TaxID=1834161 RepID=UPI0011539D9A ----VDDQIAELERRHNLLVGLYAENLDTGRRV-THRPDDMFAMCSTFKAYAVARVLQLVE -HGQLSLDHRVFVDPQAIVSNSPVTETHAGAEMTMGELCQAALQRSDNTAANLLLKAIGGP -AAVTEFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILTGDALSPRQRR -QLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAYGPDGQRILLVMLTRS -QADDAENQRAVIGELTALV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V774_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQLASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Actinoplanes friuliensis DSM 7358 TaxID=1246995 RepID=U5VZZ5_9ACTN -----TRQFRDLERRFDARLGVHAVDTGTGRTV-GHRADEPFAHASTFKALLAAVLLRRLP ---DAGLRQLVRYTEADLLEWAPVTSKHVATGMTVEALLAAAVQYSDNTAANLLLDKVDGP -KGLERELRRIGDTTTDVSRTEPSLNEATPGDRRDTSTPRALGTDLREFVLGDTLPGPRRQ -KLTDLLLGNTTGDTCIRAGVPAGWKVGDKTGSAEYGTRNDIAVVWPPTGSPLVIAVQSDR -GVPDATTDDALIAEATRVAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0004A6EDA9 ----ATAELTALEQQYDAQLGLFAVDTGSAKTL-TNRADQRMPFLSTFKGLAAAALLKAHP -LATGYFDRVVHFTEADLVTYSPVTSTKVAEGMTIAQIADAAITQSDNTAGNLLLRELGGP -QGLTAFLRTLGDQVSRLDRWEPDLNTALPDDERDTTTPAALAADYRALVLGDALGAPERE -QLTTWLKANTTGDKRIRAGVPAGWTTGDKTGTGDYGMANDAAVTWPDGGAPLVIAIQTRK -STKAAEPSNDLVAAATRLVVEK- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC05292 TaxID=2487418 RepID=A0A3R9WYE3_9ACTN -------ALRALEREYGARLGVYAWDTATGRTV-AHGADALFPQCSLFKTLAAAAVMQRFD -RDGEYLAKRIHYTQADVTRGGEITRRNIAAGLTVAELCSAAIAQSDNTAGNLLLEELGGP -AAITSFCRSLGDPVTRLDRWEPELNSAEPWVSTDTTSPRAIARTYARLVLGDALRPRHRE -LLTGWLLGNTTSKDRLRAGLPADWAVADKTGAGSYAVNNNAGIAWPPGRPPVVIAVLSTK -PEATAQREDSLVARAAALAVRKf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_015 TaxID=2175666 RepID=A0A2W1QZ89_9MICO ----TERTFAALEAEHDARLGVVAVDTGSGASV-AHRAGERFAFASTAKVFIAATVLDDAT ---PGDLDAVVPIGQGDVLSYAPVTSQRVGVGMTVRDLLTAMVRSSDNTAANLLVARVGGP -AAVQSWLCGIGDGVTRVDRVEPDLNAAVPGDERDTTTPAQFAADLRTVLLGSALDPDDRT -LLVDLMLGTTTGAGTIRAGVPAGWAVADKTGTGSYGVRNDVGIVTPPGRDPVVLVVLTSH -DTADAEPDDALVAAATRTVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. ET3-3 TaxID=2675851 RepID=UPI0012FB7C0B ------AAFRGLEQEHGARVGLFTIDTGTGKTL-GYRQDERFAFDSTFKGLACGALLHAHP -LATGFFGQVVHFTAADLVTYSPVTSTKVDTGMTVTELCEAAITRSDNTAGNQVLKLLGGP -GAVTTFLRSIGDQVTRMDRWEPDLNTNIPGDDRDTTTPAALADDYRKLVVGDTLGEPERT -QLTAWLLANTTGDARIRAGLPADWKTGDKTGAGDYGTANDVAVTWPAGGAPLVIVVLTTK -PDQAAAGDNPLVAAVAKEAV--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=A0A1L3F2X3_BRAJP -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLADTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVAGEALSPAART -QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKGPILIAAYTQG -GTPNAAQIEAVFARVGRMVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces thermolilacinus SPC6 TaxID=1306406 RepID=A0A1D3DN36_9ACTN -------LLRALELTHDARLGAFAYDTGTGRTV-AYRADERFPMASLFKTIAVAAVLRDLD -RDGEVLARRVHYTAQYVKDYSPVTEENVANGMTVAELCDATITRSDNAAGNLLLRELGGP -TSVTRFCRSIGDDVTRLDRWEPDLNSAEPWRVTDTTTPRAIGRTYGRLVLGNVLPAHDRE -RLTRWMLANQTSDERFRKGLPEDWLLADKTGGGGYGSNNNAGVAWPPGRPPVVLAVQTTR -FTPDATADNELVAEAARLLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Cohaesibacter haloalkalitolerans TaxID=1162980 RepID=UPI000E650250 --qDLKQTITSWETRLGARIGVTLRATPSDSLF-AYKADQRFPMASTFKSLMCGAVLARVD -AGSVSLSDRVTYQADQLQSYSPITKDHVESGMDVADLCEAAITLSDNTAANLMLEKVDGP -AGLTTFLRTIGDETTRLDRWEPDLNEGIDGDPRDTTTPDAMTLSLSRLLFGETLQPASAG -QLRQWMIDDKVAGALIRPHLPEGWIIGDKTGTGGNGTRGIVAFLKKPDGEAYVTAIYVTA -TDADITLRNEAISDIGRAVIDE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella variicola TaxID=244366 RepID=A0A649UHQ6_KLEVA ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGVEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETALNEALPGDARDTTTPASIAATLRKLLTAQHLSARSQQ -QLLQWMVDDRVAGPLIRAVLPPGWFIADKTGAGERGARGIVALLGPDGKPERIVVIYLR- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Allokutzneria albata TaxID=211114 RepID=UPI00069490E7 -------------------MGVFAIDTATGKTV-SHRENDRFAMASTFKAYAVAALLKRHG ---TEVLSKRVHFTQQEIVTYSPVTEKHVGTGMTVGELCGAAITKSDNTAGNQMLKLLGGP -GELTKFAKSIGDGTTRLDRWETELNTAIPGDERDTSTPKALGSAYRDLVVGDVLPPAERE -QLKKWLLTNTTGGERLRAGIPKEWSIGEKTGTGDYASANDVGVAWTEKGTPIAIAVLTTK -DTKDAKADNALLARTAKLIVE-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. CNY228 TaxID=1169159 RepID=UPI000362D3F5 ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSCRIFYTQDDVAQGAPETGKNLANGMTVEELCEVSVTASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=UPI0002F2160A ----LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP -QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEGAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2580 TaxID=1463841 RepID=UPI0004C5F839 ----VVRQLRALEREYGARLGAYALDTATGRTV-LYRADELFPMCSLFKTMAAAAVMRDLD -RDGEFLARRVHYTLDDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNAAANLLLRELGGP -TAVTDFCRSVGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYGRLVLGDALAPRHRE -LLTRWLLANTTSGDRFRAGLPVDWVIGDKTGSGSYGTSNNVGIAWPPGRPPVVLSVLTTR -PEASAPRADALVAKAARTLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-104 TaxID=1609135 RepID=A0A0F4IJI2_9ACTN ----AARRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF31_9BACT ---KLTEVVQSEESALQARVGMAVFDANTGMTW-QYRGDERFPLNSTHKVFSCAAMLAKVD -GKHLSLDQSVSINRGMLVTYSPITEKSLSPKITLGKVCQAAVSYSDNTAANVVFDAIGGS -AGFNAYMRSIGDEQTRLDRKEPELNEATPGDVRDTTTPNAIVSSLRKILLGDVLSDPSRS -ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ -TKASMQASNQAIARIGAVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces thermolilacinus TaxID=285540 RepID=UPI0003C77446 -------LLRALELTHDARLGAFAYDTGTGRTV-AYRADERFPMASLFKTIAVAAVLRDLD -RDGEVLARRVHYTAQYVKDYSPVTEENVANGMTVAELCDATITRSDNAAGNLLLRELGGP -TSVTRFCRSIGDDVTRLDRWEPDLNSAEPWRVTDTTTPRAIGRTYGRLVLGNVLPAHDRE -RLTRWMLANQTSDERFRKGLPEDWLLADKTGGGGYGSNNNAGVAWPPGRPPVVLAVQTTR -FTPDATADNELVAEAARLLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C190B7 ----HRRRFADLEREFDARLGVYALDTATGTTL-AHRADERFAFCSAFKALAAAAVLDGNP ---LSHLDKRVRYSRADLMKHAPVTARHVDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP -DRLTAYARGLGDKVTRMDRVEPAITQATPGDPRDTSSPRAFGGTYQKIVIGDALPGRKRA -FLLDLLKRNATGAERIKAGLPRGWTIADKTGTGDHGTLNDIAVLWPPRSPPVLLAIMTSK -AAKDAPYDQALLAEAAEYVT--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0K2IMW5_STEMA ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia uniformis TaxID=53432 RepID=UPI0009FE5F05 ---ALDDQLLALERKFDARLGVYAVATGSGSAI-AHRADERFAFCSTFKGLAAAAVLARNP ---LSHLDTVVDYTDADLMKSAVITSRHVGTGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYLRGLDDTVTRMDRIEPSITEATPGDPRDTTSPRAIGTDYRKIVLGDALPEERRA -FLRDLLERNLTGAQRIRAGLPADWRVADKTGTGDYGTLNDIAIAWPPDTAPLVISIMSSK -PTRDAEYNQALLAEAAEYV---- ->[subseq from] Beta-lactamase n=1 Tax=[Pseudomonas] geniculata N1 TaxID=1167641 RepID=A0A0L8A666_9GAMM ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=UPI000C195A8E ----AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD -HDGTFLSKVIHYTQLDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDRADRT -RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR -PEPDAEADDAVIAETAALL---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2W6JQC9_STEMA ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVLGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISNEQRAGVLAQVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Root369 TaxID=1736523 RepID=A0A0Q6X7J8_9ACTN ---DVTARLRALEERYDARLGVFAHHLATKRSV-RFRAGERFPMCSLFKSLAAAAVLRDLD -RDGEVLARRIHYTEDDLVIGSDQTAARLAEGMTIAELAEVAITYSDNAAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRCTDTTSPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSVDRFHAGLPKTWTIADKTGSGSYGTANDVGVVWTDAGDPIVLAVLSTM -PAQDAVRDDALVADAARAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix espanaensis TaxID=103731 RepID=UPI0009FDC8A0 --------WAGLERKFDARLGVYAVATGSGATF-AYRADERFAFCSTFKGLAAAAVLQRNP ---LAHLDTVVTYTDADLMKSSTITREHVATGMTIRDLCDAAVRYSDGTAGNLLVRDLGGP -AGLTAFLRGIGDGVTRADRTEPALTEAAPGDPRDTTSPRAIGTDYQRIVLGDVLPADKRA -FLRDLLERNTTGARRIRAGVPLGWVVADKTGTGEYGTVNDIGLGWQPNAAPLVIAVMSSK -TTTDAKYDEALIAEAAAQVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. CB01950 TaxID=1703930 RepID=UPI0009FB799E -----AESFRWLEQHFGARLGVYVLDTGSGREV-AYRADERFAFASTFKALAAGALLRRAS ---DADLDKVVTYRQEDVLTWAPVTSEHVATGMTVRDLLAASLDYSDNTAANLVTDQLGGP -AALQQALRELGDPTTEVSRTEPGLNSATPGDTRDTSTPRALAADLRRYVLDDVLPAARRQ -LLTELMVANTTGGPYIRAGVPAGWKVGDRTGNAAYGTRNDIAVLWPDGGAPVVVAVLSDR -PRQDAASDDALIAQATGAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A386U752_9MYCO ---DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRAEERFALCSTFKAPLVAAVLHQYP ---LSYLDQRVTFSKADISSPSPIAEQHIDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP -AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRP -MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI -AGYDAQPNEAFVADAARIVAS-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QE52_STEMA ----AASDFAALEKACAERLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA -GAISYDQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NJZ9_9ACTN ----QHSRLVELERRFDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAILHNHS ---MPHLETVVRYSRADLMKSAVITGQHVATGMTIRQLADAAVRYSDGTAGNLLLRDLGGP -AALTAYLRSLGDSVTQMDRIEPEIVSAIPGDPRDTTTPRAIGTDYQKIVLGDALPADKRE -FLKDLLIRNTTGARRIRAGLPTGWTVADKTGTGDYGTINDIAIVWPPGSAPLVISMMSSR -AAREADYDQALLAEATAYVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes sp. LAM7112 TaxID=2486853 RepID=UPI000FD7F720 ----VSREFGELERRFGARLGVYAVDTGTGRTV-SHRGNERFAYASTFKALLAAVLLRRLS ---DAELRRVVHYTEADLLEHAPITSKHVATGMPVEALIAAAVQYSDNTAANLLLAEIGGP -KGLQRELRKINDNTTVVSRTEPTLNGATPGDKRDTSTPRALGADLRKVVLGDVLPGPRRQ -KLADLLIGNTTGGPYIRTGVPAGWKVGDKTGAGGYGTRNDIAVVWPPTGSPLVIAVQSDR -GMPDAPSADSLIAEATKVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) TaxID=1081613 RepID=A0A0B5ESZ1_STRA4 ----QHKQLAALERKFGARLGLYALDTGTGATI-AHRADERFAFCSAFKALAAAAVLDRNP ---LSHLDTLVRYTEDDLMKHAPVTARHLDTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -EELTAYARGLGDRVTRMDRTEPAITEATPGDPRDTSSPRAFGTSYRKILLGGALPTAKRA -FLRDLLERSTTGARRIRAGVPRGWTVADKTGTGDYGTLNDIGVLYPPKSAPLLLALMSSK -PAEDAAYQEELLAEATAYAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces qinzhouensis TaxID=2599401 RepID=A0A5B8JH23_9ACTN ------RAFAALEKEFAARLGVYAIDTGSGRTV-LHRPDERFAYASTCKALIAAAVLRKHS ---LREMRRRVSYGREVLQPHSPITERNVGKGMTLSELCDATVRYSDNAAANLLFDELGGP -RGLQTELRSVGDRITRCDRYEVELSDAVPGDLRDTSTARALATDLRTYVLGNVLPPEKRA -VLADWLKRNTTGDQVIRAGTPDGWQVGDKTGTGGYGTRNDIAIVWRPKAAPIAIAVLSRK -DVKGAKHQDALIARAAEVALKAf ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA29D59 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAE--------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus sp. E9 TaxID=1742575 RepID=A0A1E5K2K1_9BACI -----SEAFKKLEDEFDVKLGVFAIDTGSNKEI-NYQENDRFAYASTFKPLVVGAILQTKS ---DPELQEVIRYTEEDLVTYSPITEKHVDEGMTLLEISDAAIRYSDNTAANLLLEAIGGP -DELETKLRDIGDETIEVDRYETELNEATPGDIRDTSTPKAMANSLQQYVLEDVLDADRRE -ILTNMLINNTTGDALIRAGVPEGWTVGDKTGAGGYGTRNDIGIIWPEDNEPIVIAIMSSR -DVEDADYDDKLIEKATKVVVKE- ->[subseq from] Class A beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A428ZKJ2_KIBAR ---------FELERKFDARLGVYAVATGSGVTI-AHRADEQFAFCSTFKGLATAAVLHRNP ---MAHLDTVVTYTEADLMKSSAITKRHVATGMKIRDLCDAAVRFSDGTAGNLLLRDIGGP -AQLTAYLRGLGDDVTRMDRIEPAITEAKPGDPRDTTTPRAIGTDYQRIVLGDALAADKRD -FLRDLLERNVTGAKRMRAGVPQGWRVADKTGTGDYGTLNDIGIVWPPAAPPLVVSIMSSK -SAADAKYDEAVIAEAAAYVVN-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonas translucens pv. translucens DSM 18974 TaxID=1261556 RepID=A0A1C3TRY2_XANCT --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLPVRAADMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTHFLRTLGDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRALLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CA-126428 TaxID=2073158 RepID=UPI000CD039C6 ------PDFAPLERNFDARLGVYALDTGSGREI-AHRADERFGYASTHKAFSAGAVLQRTG ---LDGLAKKLTYTRADLQPNSPVTEKHVTTGLSLREAIDAALRYSDNTAANLLFRELGGP -AGLAAALRGVGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAGSLRAFALGPALPPEKQT -VLTDMMRANTTGAALIRAGAPAGWAVADKTGTGSYATRNDIAVVWPPERAAIVLIVMSSR -QAEKADHDDRLIAQAAKLALDAf ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium hainanense TaxID=52131 RepID=A0A1C3VCN5_9RHIZ -----EARLAALEAKHRGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAAVVLARVD -KRKEKLDRRIHYAKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGGP -GAITTFCRSLGDEITRLDRTEPTLNYDNPNDQRDTTTASAMLENLRRLLFTDVLTPASRS -QLAAWLITNKTGDTRLRAGLPMDWLVGDKTGTNGAGNANDIAVLWPANRAPIIVTAYCEI -PEIAADERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C5B381 -----HQRLSALERKYGARLGVYALATGTGATV-THRADERFAFCSTFKGMAAAAVLHRRP ---LSHMDTVVTYTEADLMKHSPVTGKHVATGMTLRQLCDAAVRFSDGTAGNLLLREIGGP -GALTAFVRGLGDTVTRMDRIEPAITEATPGDPRDTSSPRAFGTDYQKVVLGNVLAADRRA -FLRDLLERNATSAQRIRAAVPRGWTVANKTGTGDYGTLNDIAVVWPAKSSPLLISIMSSK -STKDAAYDQALIAEAAKYVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Lechevalieria deserti TaxID=531939 RepID=A0A316HWG9_9PSEU ----ISGKLRDLEQQHGARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRRDH --NGALLGKVIRYTQEDVTKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLKELGGP -TAITRFSRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRTDAD -QLTKWLLANTTGGNRIRAGLPTAWRWGDKTGTGKYGTTNDVGIAFPPGRSPIVIAVLSTK -SVQDAPADEPLLAKTAELVAGTf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SceaMP-e96 TaxID=1100824 RepID=A0A1C6LMN3_9ACTN ----FASEFKKLERKYDARLGVYAVDTGTGREV-AYKDGERFSYNSTFKALAAGAVLRKHS ---PSAMNRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP -KRLEGVLKGIGDDVTRMERIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGGVLDKGDRK -QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR -FKKDVDFDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus boraciitolerans JCM 21714 TaxID=1298598 RepID=W4VPL9_9BACI -----EQEFEKLEKEFDVRLGVYAMDMGNNQVI-EYNSEERFAYSSTFKVLAAAILLKEND ---FKDLEKVITYNEDDLVTYSPVTEKHVDSGMTLLEISEAAIRKSDNTAGNLMLEALGGP -DKFKQALRDIGDDITEPARYETELNEFSPDSNKDTSTPKAMASSLKKVALDDFLPNDKRE -ILIDWMKGNATGDELIRAGKPDGWVVGDKSGAASYGTRNDIAIVWPPNREPIVIAVMSRR -DTEDAEYENELIAKTSEIILHSf ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces sp. WM6386 TaxID=1415558 RepID=A0A0F5VN12_9ACTN ---RVSERLRELEQRHGARLGVFARNLGTGRTV-RHRADELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALNRRDRE -LLTHWLLNNTTSGTRLRAGLPKTWTVADKTGGGSYGTNNNVGIAWTPEGTPLVLAVLTTM -PEQSAARDDLLVADTAKALAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6C8X6D0_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPVSRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGVPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI97-07 TaxID=1522762 RepID=A0A3N6GI37_9ACTN ---RTARAFRGLEREFDARLGVYAVDTGSGLSV-THRSDERFAYASTCKALLAGALLDAHP ---LRRLDRRVRYGPGDLVANSPVTEEHVRSGLSLRALCEAAIRFSDNTAANLLFRELGGP -GGLQDALVALGDRTTRCDRYETDLSEAAPGDPRDTSTPRALAADLRAYVLGDVLAPDARA -LLTDWLRRNTTGDTLIRAGTPDGWVVGDKTGTGGYGTRNDIAVVWPPGSAPITIAVLSRR -AAHGAEPQDALVARAAGVAL--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066B85BA ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVSVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA486 TaxID=1298880 RepID=UPI0003FBC785 ---AVTGRLKKLEREHGARLGVFAHNTRTGRSV-AHRADERFPMCSTWKPLAVAALLKDRD -RGGDRLAEHIRYSRSDLEDHSPITGTNLADGMTVRQLCDATLRYSDNTAANLLLRELGGP -AAVTRFCRSVGDDVTRLDRWEPELNSAEPGNVRDTTSPRAVGRTYMRLALGDVLGRAERL -QLTDWLKGNTTGGEGLRAGLPEGWTLGERTGAGDYGTDNDVGVAWTADQVPIVLAVLTTK -RSADAEPDHPLIAKTARILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=UPI0005277F88 -----DGAFKDLELHFGARLGVYAVDTGSGREV-AYRSDERFAFASTIKSLLTGALLRTAS ---DQELDKVVTYRQDEVLTWAPITSRHVDTGMKVRDLAAAALEYSDNTAANLLMTELGGP -ETLQRTLRELGDPTTNVNRNEPTLNEATPGDPRDTSTPRAFAADLRRYVLGDVLTEDRRR -MLTDWMVGNTTGAPFIRAGVPVDWKIGDKTGNGGYGTRNDVAVAWPSGGSPVVLVMMSDR -GKADATSDDALIAEATKAVVT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALA7_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. CC120223-11 TaxID=1378090 RepID=UPI000BCE81BD -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNSEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A149ZQJ9_9NOCA ----LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKSVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP -QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEGAQGNNQAIADTTAAVIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2BVL4_STRVZ ---RLASRFTALERKHGGRLGVYALATGTGATL-THRADERFAFCSTFKTLAAAAVVHHRP ---LDQLDKRVTYTAADVDSISPVTEKHIATGMTVGELCDAAIRYSDGTAGNLLMREIGGP -AGLTDYLRGLGDKVSRMDDHEPELNDVPPGDPRDTTTPRAVAADYRALVLGAALPDAKRA -LLAGWLGRNATGARRIRAGVPKGWRVADKTGTGNWGRANDIAVVRPPDADPLVLAVMTDR -PGRDTPPVNAFIAEAAKLVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013BC95C9 ----ADEEFAELENTYDARLGVYAVDTGANQEI-AYRADDRFGHASTFKALLCGVVLQENS ---IEDLDRVITYTSDDLVFHAPITEQHVETGLSIGELCEAAVRYSDNTATNLLLDEVGGP -SGLGRALQENGDDVISVDRYEIEMSSAVPGDTRDTSTARSIGTSLRTFVLDDALSGDKQA -LLTAWLVENTTGDDLIRAGLPDDWVVGDKTGNGGYGTRNDIAVAWPPGRDPIVIAVLSSR -DEEGAEHDDQLIADTAEIIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. KCTC 12332 TaxID=1793721 RepID=A0A126NGE0_9GAMM ------ADFATLEKTSGGRLGVCLWHPASGARY-GHRMDERFPMCSTVKFPLAAAILHRVD -AGKLSLDQRVAVRQGDIISHSPFTERHVGKDMTVRDLCRATLIISDNAAANLLLPLIDGP -AGLTAFLQAQGDRITVSARNEPELNHFAPGDPRDTTSPAAMAGNLQRFLLGDVLSPASRQ -QLADWLIDNQTGDARLRAGLPQGWRVGDKTGSNGQDTSNDIAALWPLGGAPWLLSCYLQG -SALDDDGRDGILRQVGELA---- ->[subseq from] class A beta-lactamase n=1 Tax=Xenorhabdus TaxID=626 RepID=UPI00069AE9B5 ----IIHQLSILEKNANGRLGVVLLDTSDHSII-SYRENERFPLCSTSKLMTVSAILQKNE -TNAHLLNQRVHYQQSDLVEYSPMTEKHLKEGMTLGELSAATLQYSDNTAMNLLLNQLNGS -HEVTRFARTIGDHYFRLDRREPELNTAIPGDDRDTSTPQAMAKSLYNLVLGTALATTQRE -QLTEWIKGNTTGGTSIRAGLPKNWIVGDKTGRCDYGTTNDIAVIWPPDRAPLVLVTYFTQ -PNKEASARPDVLAAATRIVT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBD1_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLNQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPHDTTTPAAMAATLQRVVLGEVLQPVSRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID14478 TaxID=2706073 RepID=UPI0013DAE851 ----TARRFAALERRHGARLGVFAQNIRTGAVA-AHRADERFPMCSAFKTLAVAAVLRDLD -RDGRFLDRRIRYTQADVDRGAPVTGKNLAHGMTVAELCGAAISYSDNTAANLLLHELGGP -AAVTRFARSAGDRVTRLDRIEPELNSAEPGRSTDTTSPHAIGATYARLVLGDVLDPEDRV -RLSGWMFANTTSGKRFRAGLPDGWVLADKTGTGSYGTANDVGIAWTPGGDPVVLSVLTTK -PDQDAEPDDQLVARAAELIA--- ->[subseq from] Carbapenem-hydrolyzing enzyme n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A096ZH67_ENTCL ------DEIKDLEKDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI0013D83EA2 ---QCNSAFSQLESDYNVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP -SGFKSALNQLGDNVTQPARIEPELNEAMPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQVSKIVFDSf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LamerLS-316 TaxID=1157630 RepID=A0A1C6MIX1_9ACTN -----EQAFGGLERKFDARVGVYAVDTGSGVTV-THRPDERFAYASTCKALMAGALLKTRP ---LPQLDRRVRYGPDDLVANSPVAERHVDTGLTLRELCEAAVRYSDNAAANLLFHELGGP -RGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALASDLRAYTLGGALGTDARA -VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR -DTRGAEPQDALVAEAARVALDAf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB13_STEMA ----TANDFAALEMACAGRLGVTLLDTASGRRL-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVRDADLLTHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVALGDVLQPASRQ -QLSDWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISNEQRAGVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066BE8AA ----AASDFAALEKACAERLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA -GAISYDQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBA4A7 -----EAELAALESRHPGRICVSILDMASGTRI-EHRARERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRAPVIVTAYCEI -PAIAADERNGIVAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) TaxID=479435 RepID=D2PTW6_KRIFD --------FGKLEKKYGARLGVYAVDTGSGREI-AHRADERFAYASTFKALAAGAVLRKYT ---LQGMGKVVKYSESDLLANSPITEKHVATGMTLRELCDAAVRYSDNTASNLLFDALGGP -KGLDAVLAELGDNVTQMEQRELELSVWDPSNPRDTSTPRAFARNLRTFVLGDALRAPERA -QLTTWLRTNLTGAELIRAGMPKGWVVGDKTGTATYGGRNDIAVVWPPGRAPIVLAIFSNR -PAAEAEHDNRLLAEAARVVAAAy ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MH181796 TaxID=2339228 RepID=UPI00129D1ECB -----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPGAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9RBQ0_STEMA -----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPGAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. AA4 TaxID=1896961 RepID=A0A2K8LSX2_9PSEU -----QPDFAALEKAFDARLGVYAIDTGNGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLARTVTIRQSDLVSNSPITEKHVGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRAWAKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSAEYATRNDIAVVWPPNRAPIVLAVLSDR -PRKDAKTDDKLIAQAAAAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Pyruvatibacter mobilis TaxID=1712261 RepID=UPI001371718B ---QLDADLAALEARHGGRLGVAILDPATGAAT-GHRADERFLLMSTFKALAAAFVLTRVE -NGDEQLDRRITHSEADLIPWSPVTKHHTGAPMTVAALCDAAVTWSDNTAANLLLESVGGP -ASLTAYLRGLGDDMTRLDRIEPALNHDGPDDIRDTTTPAAMAATLRTLLFTDALAPASRD -QLTAWLITSKTGGTRLRAGVPDTWLVGDKTGTNTEGAAADIGVIWPLGHGPLIIAAYCDM -PSLTGDARNAVFAEVARLAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium betae TaxID=244734 RepID=A0A4Q1VDG1_9BRAD -------ELESYERESGGRIGLYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLEYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSQPGDPHDTTTPVAMAGNLKRLVVSEALSAASRA -QLTEWMVGCKTGANRLRGGLPAAWTIGDKTGNNGKDASGDIAVAWPKPDRPILIAAYTQG -GTPTAAQIEAVFARIGRMVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ASS1 TaxID=2282124 RepID=A0A4P6W2W3_9GAMM -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAASVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPGSRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISNEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=2 Tax=Agreia sp. VKM Ac-1783 TaxID=1938889 RepID=A0A1Y6FDE4_9MICO -------AFAQLEQEFGARLGVYALDPATRAEV-SYRADERFAYASTFKALAAGILLKTVP ---DDQLDEIVSYDSSQLLPNSPVTEENVDEGMTLRAVAEAAVRFSDNTAGNIMLERLGGP -EGFTQALRELGDTTTSSDRIETELNSAIPGDVRDTTTPRAFALDLATLLTTDALGAAQQA -QLIDWMTGNATGAELIAAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR -STEDADYDNALIARAAEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9864D --hALEARVAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGRP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 3213.3 TaxID=1855348 RepID=A0A1H5B107_9ACTN ----VSARLAALEEQHTARVGVFAHHLGTRTTV-VHRADELFPMCSVFKTLAAAAVLRDLD -RHGEVLYKVVHYTEADLVDGSDRTRARLADGMTVEQLADVAIRYSDNGAGNLLLRELGGP -TAVTRFARSLGDPVTRLDRWETELNSAEPDRITDTTSPRAIAGLYGRLVLGDALRRPDRD -RLTAWLLNNTTSAARFRAGLPASWTIADKTGSGDYGTANDVGIAWTEAGDPVVLAVLTTK -PTPDAPYDNQLVADTAELVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces silvensis TaxID=1765722 RepID=A0A0W7X578_9ACTN -----AQAFKQLERKFDARLGVYAVDTGTGREV-AYNDGRRFAYNSTFKALAAGAVLRKNT ---LAGMDRVVKYSKDDLLANSPVTEKHVDTGMSLRALCDAAVRYSDNTAANLLFDELGGP -KGLDAALERLGDHVTRVERIEPFLSRWVPGEKRDTSTPRTLAKDLRAYVLGDVLAEPQRA -LLTRWLKTNTTGDHVIRAGVPKNWVVGDKTGTGTYGARNDIAVVWRPDAAPLVVAILSHR -ADKDAAPDDRLIAESASVVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID5464 TaxID=2690293 RepID=A0A6B1KRL9_9ACTN -----TARLRELEREHTARLGVYARNMRTGRTV-AYRAGERFPIASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQDCVTKYSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP -TAVTRFARSIGDGVTRLDRWEPDLNSAEPWRVTDTTSPRAIGLSYARLVLGDVLEPRDRA -RLTDWLLRNTTSTEKFRKGLPPEWLLADKTGQPEYGGAHDVGITWPPDGTPIVLSVLTMQ -PERDAPADNALVARTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB41_STEMA -----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR -RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ -QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPVGGAPWVITAYLQA -ADISNDQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Opitutaceae bacterium EW11 TaxID=2161865 RepID=A0A2T6DZZ5_9BACT ---ALSSLLSALEERCAGRLGVAVLDPQTGEWL-GWREDERFAMCSTFKLLLAASILQRVD -RGLERTDRSILVPPKPLLVTSPVTEQHAGERMPVGALCEAIVTRSDNTAANLLLETVGGP -DAVTRFARSIGDEVTRLDRPELALNEATPGDPRDTTTPRAMARNLETLLVKDLLAPASRE -QLIAWMVESRSGIAKLRSALPAGWRAGDKTGANGSTTSNDIAIAWRPDGRPLLIAAYLTE -CPGPEAKRASVLAETGRLVFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea terrae TaxID=2200761 RepID=UPI000DD4453D ----ITGKLRDLERQHNARLGVFATDTGTGRTV-LHRADELFPMVSTFKTLVAAAILRRDH --DGTLLNKVIRYTQDDCTKYAKITEKNLANGMTVSALCDATITYSDNCAANLLMRELGGP -TAITRFCRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRSDAD -QLTKWLLANTTGDHRIRAGLPAAWRWGDKTGTGKYGTTNDAGIAFPPGRAPIVIAVLSTK -SVPDAGADEPLVAKTAELVAGF- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces misionensis TaxID=67331 RepID=A0A5C6K2H4_9ACTN -------ELDDLERRFGVRLGVYARNVRTGRVL-AHRAGERFAHCSVFKAFAAAAVLRDHS --GCAPLDKVVHYPPHALLPNSPRTEENQETGMTVADLCAAAIRYSDNTAGNLLLQQLGGP -AGLTRFFRSLGDRVSRQDRWEPELNTAVPGDLRDTTTPEAIATGIERLILGRALAPSDRE -RLVTWMKGNTTSGARFRAGLPEGWTLADKTGTGFYASAHDIGVAWTTRHTPVVLAVLSTG -NEKDAPVDEALIREAARIVAR-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A1D7YMN7_9ACTN ---AVEAELAELERRHGARLGVYARNVRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --GCAPLDKVVHYPPHDILSNSQHTAEHVDTGMTVADLCAVAIQFSDNAAGNLLLREIGGP -AGLTRFFRSLGDRVSRLDRWETDLGSAIPGDLRDTTTPQALGGSFERLTLGRALAGADRE -RLVTWLKGNTTSAARFRDGLPRDWVLADKTGTGDYGTANDIGVAWTTRNTPVLLTVLSTK -SAQHAPADDALVAEAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Ruegeria sp. AU67 TaxID=2108530 RepID=UPI000D69E455 ---PLTETVQSWERRLDARIGLLLYDPSNEWEV-SYRADELFPMSSTFKTLLCGAVLAEVD -AGTESLSDHVTYQTTDLVDYSPVTSKHVETGMTVGALCEATMTISDNAAANLLLRRLDGP -AGLTEFLRTNGDDITRLDRWETALNEATPGDPRDTTTPRAILATLDRLLFGQALSPASSA -QLRQWMIDDQVANGLIRAHVPDGWTIGDKTGAGGHGSRAIVAFLQTSEPRTYLAAIYLTE -SDAPFPERNAVLSDIARAMIS-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. 278 TaxID=2479851 RepID=A0A3R8UDF4_9GAMM ------ADFTALEKASGGRLGVTLLNTATGKRF-GHRQDERFPMCSTFKFVLAATVLHHAD -RGTLSLDRRLPVRAQDLLSHAPITKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVIGGP -AGVTSFLRANGDAVTRNDRLEPEMNEFAADDPRDTTSPAAMAASLQRFVLGDVLQPASRL -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAMLWPLGGTPWVLTTYLQG -ATVDDAGRNDVLRQAAVI----- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf113 TaxID=1736259 RepID=A0A0S9R7D0_9RHIZ ------AAFEQIARDLGGRVGITVLDTGGGPSL-QLAADAAFPLCSTFKLLLAAAILARVE -AGQDQLDRRIAYTAADLDVYAPITGGALKEGMSVAALCAAAMVWSDNTAANLLLGALGGP -AALTAYCRSLGDSVTRLDRTEPDLNSAEPGDPRDTTRPAAMAATVRTILLGDALTPGSRA -RLEGWMTAARTGTKRLRAGLPGDWSVGDKTGSGAYGTANVVAILRPPARPPLIAALYLTG -STASAEARDAAHAAIGRVIATAy ->[subseq from] Beta-lactamase n=1 Tax=Gracilibacillus kekensis TaxID=1027249 RepID=A0A1M7QR65_9BACI -----DEEFSKLENEYDARLGVYALDTGNDQII-TYNSEERFAYASTFKVLAAALLLKQNN ---IQDLEEIVTYKEEDLVTYSPVTEQNVGAGMTLLELSEAAIRKSDNTAANLMLEALGGP -DRLKQALREMGDDITNPERYETELNDFTPGSNKDTSTPKAMATTLKHIVFDDFLPKDKRE -LLLNWMEGNATGDALIRAGQPEGWVVKDKSGAASYGTRNDIAVVYPPDREPIVIAIMSRR -DTEDAEYDDELVAQAAKIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3D4TPX1_9GAMM ------TDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDPVSRSDRLEPELNTFAEGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISYEQRAVVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. BoFeN1 TaxID=1231053 RepID=A0A369VNV6_9BURK ---QWSDALAGIERAAQGRLGVAMLDTGSGLAL-GWRQHERFAMASTFKLVLAGWMLALVD -QGKERLDARVHYPVADVVAYSPVSGPRAGDGLTVGELCAATVSLSDNTAANVLLARHGGP -VGFTAFVRSLGDGATRLDRTEPTLNEAAVGDPRDTTTPLAMLQTIRKLVLGGALTPASRA -WLQRWMVETTTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVLWPPSGAPVLVTCYLTR -STATPQQRDAAIAQVARAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=A0A2G6XVF6_9ACTN ----AVRKLRDLERRHGTRLGVFGWNTVTGRTV-LHRANERFPLCSTSKTMAIGAVLRDLD -HDGTFLSKVIHYTQLDIDRAAPVTGQNLAHGMTVADLCGAAVSYSDNTAMNLLLAELGGP -AAVTRFCRSLGDTVTRLDRCEPELNSAEPWRVTDTTTPRAIGKTYARLALGNALDRADRT -RLTGWLLANTTGGKRLRAGLPEGWTVGDKTGTGRYGTTNDVGIAWPPGQGPIVMAVLSTR -PEPDAEADDAVIAETAALL---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00115EEB57 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RMPALLDRRVPVRDADLLSHAPVTRRHAGKDLTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=A0A3R5YRI4_9ENTR --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLAAQKLGGP -QKITAFFAGLGDNVTRLNRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLGDALKPESRA -QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAHGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0007F0223E -----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR -RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ -QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPMDGSPWVITAYLQA -ADISNDQRASVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=UPI000C1534B6 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RMPALLDRRVPVRDADLLSHAPVTRRHAGKDLTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMATTLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes friuliensis TaxID=196914 RepID=UPI000427440E -----TRQFRDLERRFDARLGVHAVDTGTGRTV-GHRADEPFAHASTFKALLAAVLLRRLP ---DAGLRQLVRYTEADLLEWAPVTSKHVATGMTVEALLAAAVQYSDNTAANLLLDKVDGP -KGLERELRRIGDTTTDVSRTEPSLNEATPGDRRDTSTPRALGTDLREFVLGDTLPGPRRQ -KLTDLLLGNTTGDTCIRAGVPAGWKVGDKTGSAEYGTRNDIAVVWPPTGSPLVIAVQSDR -GVPDATTDDALIAEATRVAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=UPI0009DD2B2D -----TGKLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMVSTFKTLVAAAILRRDQ --DGSLLNKVIHYTEDDCIKYAKITEKNLANGMTVSALCDATITFSDNCAANLLMRELGGP -TAVTRFCRSIGDPVTRLDRWEPDLNSAEPGRVTDTTSPRAIGQSYARLTLGHALNRADAD -QLTKWLLANTTGDHRIRAGLPADWRWGDKTGTGKYGTTNDAGIAFPPGRSPIVVAVLSTK -PSKDAPADEPLLVEAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens subsp. sonorensis TaxID=1173677 RepID=A0A5C4RDH2_PHOLU ---RLATVVKQEEQTLNARIGVAVIDTASDKIV-SYRGNERFPLNSTFKALLCGVLLSEVD -KGKVALTDAIQFNKTELVEYSPVSEKFVAPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP -AAMNLFFSGLGDSVTHLDRYEPELNSAIPGDERDTTTPVAVSQTLQKLTLGEVLKPSSRQ -QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKNSSPLIVAIYITQ -TEATIVQSNEAIARIGKIL---- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MMLR14_014 TaxID=1898744 RepID=A0A1S2JE75_9MICO ---ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGERFAFASTIKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -HAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PCS3-D2 TaxID=1460244 RepID=A0A024YWM5_9ACTN -----VRRLRALEREYGARVGAYARDTRSGRTV-RYRANELFPMCSVFKTPAVAAVLRDLD -RDGGFLARRIHYTQEDVTSGGLVTGENVAGGLTVAELCSAAIAQSDNGAANLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTTPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTR -PDAAAPHENALVAKAAEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2664 TaxID=1463842 RepID=UPI0004C62DD4 ----LAARLRELEQRHSARLGVFARNMRTGRTA-AYRADERFPMCSLFKTVAAAAVLRDLD -RDGDFLAERIRYTAQYVKRYSPCTGKNIENGMTVAELCAATICYSDNTAGNLLLRELGGP -TAVTRFCRSIGDGRTRLDRWEPELNSAEPWRVTDTTTARAIGGTYARLVLGDVLAPADRE -RLTGWLLANTTSDERFRAGLPADWILADKTGGGSYGGNNDVGIAWPPDGAPILMAVLTAK -QERDAPADHPLVAATAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces chartreusis NRRL 3882 TaxID=1079985 RepID=A0A2N9BJ55_STRCX -----TARLRELEREHTARLGVYARNMRTGRTV-AYRAGERFPIASVFKTLAAAAVLRDLD -RDGEFLARRIHYTQDCVTKYSPVTQENLATGMTVGELCDATIRFSDNAAGNLLLKELGGP -TAVTRFARSIGDGVTRLDRWEPDLNSAEPWRVTDTTSPRAIGLSYARLVLGDVLEPRDRA -RLTDWLLRNTTSTEKFRKGLPPEWLLADKTGQPEYGGAHDVGITWPPDGTPIVLSVLTMQ -PERDAPADNALVARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. 2A TaxID=2603816 RepID=UPI0013529C78 -----DPDITAIERRIGGRIGVAAGS-ADRILL-HHRADERFPMCSTFKVLEAAAVLARVD -AGSETLDAMVSYGAGDLLSYAPVTRKALAASLSVAELCAAALVWSDNTAANLLLARIGGP -AGLTAWLRGIGDPVTRLDRDEPTLNSALPGDPRDTTTPEAMRRTLGRILLGSLLAPPSRD -RLEAWMAGSQTGLKRLRAGLPRDWTIGDKTGSGDNGTVNDVAILQPPGRAPVTVAVYITG -STLPAAAVESAHAEIGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methyloceanibacter sp. wino2 TaxID=2170729 RepID=UPI000D3EB9CA ---DLASQFAKIEKKIGGRLGVAVS--GDGLKA-AYHGGERFPMCSTFKLLVVAAVLHRVD -EGDEMLSREIPVPPDAILDYAPVAKEYAGGTMTISELCEAAMVWSDNTAANLILERLGGP -EAATAYVRSLGDTVTRIDRMEPDANVFGPGELRDTTTPEAMLGDLQKLFLGDALSPLSRD -RLTEWFVANQTGKDRLRAGLPPTWRVGDRTGTGPHGTSNDVAMAWGEDGRPILIAAFLTG -SKADAAARDNALADVGRAI---- ->[subseq from] class A beta-lactamase n=1 Tax=Belnapia sp. F-4-1 TaxID=1545443 RepID=UPI0009DDF586 -----AEGLATLEARQGGRLGVAILDTGSGRML-AHRGEERFALCSTFKHLAAARVLARVD -AGEERLDRHVAYGREALVPYSPTTGPGAEAGLGMGTICEAAVVLSDNTAANLMLDSFGGP -AGLTAWLRGLGDGVTRLDRREPELNVVPPGDERDTTTPLAMARTMQRLLLGEALSTDSRE -RLAGWLVGCRTGDARIRAGMPVGWRVGDKTGTGPAPPTNDVAIAWPPGRAPVIVAAYLEG -ARGSDAERSAVLAEVGRIAA--- ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces sp. B9173 TaxID=1462558 RepID=A0A1V9WJ87_9ACTN ----VTARLRDLEAAHGARLGVFAHNVRTRRTV-RYRADERFPVCSLFKTLAVAAVLRDLP ---EGTLDRRVYWTAADVVENSPVTQEHVADGLTVAELCAAAVQRSDNTAGNLLLREIGGP -AGLTRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTSPAAIGRTYGRLVLGDALAAGDRR -RLTDWMLGTVTSANRFRAGLPPTWTVADKTGGGWYGANNDAGVAWTPDGAPVVLVVQLTE -PDREAAYDHDLIVETAKVLAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=A0A3R9DPR4_9PSEU -------DFAPLEREFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSTAAVLQRTS ---MAGLAKVLPYTSADVQPNSPVGEKHVGTGLSLRDAIDAALRYSDNTAANLLFRELGGP -AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDIRDTSTPRAMAADLRAFALGTALPAEQRT -FYTDTMRANRTGDAVIRAGTPAGWTVADKTGTGAYATRNDIAVVWPPGRAPIVLAVMSDR -KTADAEHDDRLIAQAAKLTLDTy ->[subseq from] class A beta-lactamase n=1 Tax=Roseovarius sp. TM1035 TaxID=391613 RepID=UPI000319945E ---HLAATIDRIEQELDARVGVVIRDSGSDWTV-SHRAEERFLMASTFKTMLCGAVLHRVD -EGDLDLEERIAIEAAEVLEYAPVTEKMVGETMSVGELCHAALDMSDNTATNLLIDRIEGP -QSVTAFLREIGDPVSRLDRREPDVNTFAPDDPRDTTTPEAMVSTMETLLTGGALSPQSRA -QLVDWMTDGGVTGALIRASTPAGWHVADRSGSGNF-NRNIVAMVTPPDREPYFIAIFLSD -ADADFNTRNGAVIELSKAVMQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003694502 ---DLSHEFRQLEERFDARLGIYAVDTGTGRTV-RYQANERFAYGSTYKALAAAEVLDATT ---DAELDQVVRYSADDLVDYSPITKQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEQELKGIGDNVTDAARYETELNEATPGDPRDTSTARALTEDLREYAVDDALEPTDRD -ILNAWLRGNTTGGELIRAAVPDGWVVGDKTGAAGYGTRNDIAVIWPPDRAPIVLAVLSTR -DEPDASFDNALIVEAAEEVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella cf. planticola B43 TaxID=95610 RepID=UPI0003451541 --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCSAAISYSDNTAANLVAQKLGGP -QKVTAWFADLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSHTLEKLTLGDALKPESRA -QLVQWMKDDNVADALLRASLPSGWKIGDKSGAGAHGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas lactitubi TaxID=2045214 RepID=A0A2M9QZ47_9GAMM -----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWIVTAYLQA -GALSFEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BFB25EA -----NDSFAKLEKEFDAKLGIYALDTGTNQTV-TYQSDERFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYNREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPQLNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -D---------------------- ->[subseq from] Beta-lactamase n=1 Tax=Desertiactinospora gelatinilytica TaxID=2666298 RepID=A0A2W2GP79_9ACTN ---AVRRELRALEASFDGRIGAYAIDTATGRTV-GHRAGERFPLASTFKAVVAAAVLHKAR -TDPGLLKRVVRWAAAEVEPYSPTTQKHVKSGLTIGRLCEAAITQSDNTAGNILLKEIGGP -AGLTRYFRSLGDEVSRSDRWEPEMNRWKPGEKRDTTSPAAMAHGFRRLTAGDALNAKDQA -RFNAWLLANKTGGDRIRAGLPSTWKVGDKTGTGGYGTANDVAVIWPAKAAPIVMAVYTSR -KAAEADAEEEVLAKTAAILVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-350 TaxID=1463902 RepID=UPI00068B7F34 -------LLAALEQEHAARLGVYARNLTTGRTV-RYRADEPFPICSVFKTVAVAAVLRDLD -RDGEFLARRIRYTQADIDRGAPVTGENLANGMTVAQLCAAAIDHSDNTAANLLLHELGGP -TAVTRFCRSIGDGVTRLDRWEPELNSAEPDRRTDTTSPRAIARTYERLALGRALPPAKRD -QLLAWLRANTTSTHRFREGLPQDWALADKTGTGSYGTTNDVGIAWTPAGAPVLLAVLATK -PTPAAPKDEPLVARTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis flavescens TaxID=758803 RepID=A0A1M6BSH8_9ACTN -------GFAALETEYGARLGVYALDTGTGEEV-EYRADERFAYASTHKALSAGALLAENS ---LEEMEEVVTYTEEDLVDYSPVTEQHVDTGMTLMEVIDASVRYSDNTAANLTLDALGGI -EGFTEDLRSIGDDVTEPARYETELNEATPGDIRDTSTPRAMATSLEAYTLGDVLPEEKQD -VLIDLLIRNTTGDETIRAGVPEGWIVGDKTGSAGYGGRNDIAVVWPEEGDPILISVYTAQ -DAENAEPINEIIADATEIVVDE- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. gb1(2016) TaxID=1828321 RepID=A0A652LDV4_9ACTN -----EQAFGELEQKFDARAGVYAVDTGSGLTV-THRPDERFAYASTCKALLAGALLKTYT ---LPQLDRRVRYGPGDLVANSPVTEQHVDTGLTVRELCDAAVRHSDNAAANLLFQELGGP -GGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALAADLRAYALGSALGTDARA -VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR -DARDAEPQDALVAGAARVALDAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TP-A0874 TaxID=549819 RepID=UPI000853640D -------RFRRLEREFHARLGVYAVDTGTGRKI-EHRSDERFAMCSTFKTYAAASLLRSHS -LSGPFFDRRVRIEEADLVDNSPITEARLGERMTVAELCGAAITHSDNTAGNHLLRLQGGP -GAVTRFARSIGDRATRLDRWETELNSALRGDRRDTTTPAAIGEGYRTIALGSVLPAAERK -QLISWLKANTTGDERIRAGLPDGWITGDKTGAGSFGTLNDVAVAWPADADPIVIALLSDR -SKVDAVPDNALLADAAQAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Modestobacter versicolor TaxID=429133 RepID=A0A323V4M9_9ACTN ---AVEEALAALEAEFGVRLGVHAVDTGSGEVV-EHRADEPFPYASTYKALAAGAVLDRTT ---PAQLDEVVTWTAADLVTYSPVTELHVGTGLPLRDVLAAALQVSDNTAGNVLFDQLGGT -EGFEEELRALGDTATSAERYEPELNTAVPGDARDTSTPRALATDLQALAVGDALEAEDRE -LLLGWMRTATTGTGLVRAGVPAGWEVADKSGTAAYGTRNDIAVVQPPGRAPIVLAVLSTH -PAADAEPSDEVVARAAAVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoflavus TaxID=35619 RepID=A0A0L8NMG8_9ACTN ------PRLAALERKYDARLGVYALATGTGATV-THRADERFAFCSTFKGMAAAAVLHRHP ---LSYVNTVVTYTEADLMKHSPVTRKHVATGMTIRQLCDAAARFSDGTAGNLLLREIGGP -GELTAFTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGNVLAADKRA -FLRDLLERNTTGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISIMSSK -STKDAAYDQALIADAAAYVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium sp. Ghvi TaxID=1855319 RepID=A0A1I5CIP8_9BRAD -------ELDSYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDKLAAMISYDKADLLEYAPVAKQNLAAGMSIADMCKAIVELSDNTCANLLLAHVGGP -TALTGFWRSIGDTTSRLDHNEPELNRSPPGNPHDTTTPAAMAANLKRLVTGEVLSTASKT -QLTEWMVNCKTGANRLRGGLPAAWKIGDKTGNNGKDASGDIAVAWPKPDAPILIAAYTQG -GMPSAAQLEAVFARIGRMVAE-- ->[subseq from] BlaIMI-2 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1I9W1Y6_ECOLX ------DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFYSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aurantiacus TaxID=47760 RepID=UPI0006E3F741 ------GALAELEHAHSARLGVFARNTVTGKAV-RYRADETFPMCSVFKTLAAAAVLRDLD -RRGEFLDLRIRYTDQDLTDGSPVTGENLANGMTVAALCHAAVTRSDNAAANLLLRELGGP -TAITRFCRSIGDTTTRLDRWEPALNSAEPWRTTDLTSPAAIGRTYAKLVLGDALVPRDRR -QLTEWLLANTTSTDRFRAGLPADWALGDKTGTGEYGTTNDVGIAWTPERSPVVLAVLSTT -SDPDAPMDNALVAEAAELLA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000312778C -----AKDFAALEAASGGRLGVTLFNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGTLPLDRRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V776_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDALSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLIAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SC18_KLEPN ---------------FRAAIGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIICRD -KN--------------------- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=Q0SKC3_RHOJR ---SLDATIDALEAQYSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGAPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDVGDGGTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPLVLAILTDS -LTQDAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces triticisoli TaxID=2182797 RepID=UPI000DDBACDB --kEITGQLRNLERAHSARLGVFAQDPATGRTV-LYRARELFPMCSTFKTIAVAAVLRDLD -RDGTFLAELIRYTDKDVTEYAPITGDNLAGGMTVADLCAAAIDHSDNAAANLLLRELGGP -SAVTRFCRSIGDSVTRLDRWEPDLNSAEPGRVTDTSSPLALGRTYSRLILGDALEEADRD -RLTLWLLNNTTSGNRFRAGLPKDWTVADKTGTGNYGTTNDVGIAWPPGQGPVVLAVLSTK -HDSAAPADESLVADTAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. CCGE-LA001 TaxID=1223566 RepID=A0A120HP83_9BRAD -------EFEAYERESGGRIGLHAENLASGAKL-VWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYREADLLEYAPAARQNLTAGMSVREMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSRPGDPRDTSTPAAMAGNLRRLVLAEALSPASRA -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDIAVVWPKPDTPILITAYVQG -GTPSAAQIAAVFARIGRMVAD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0N0TUG9_9ACTN ----HRRAFRALENAFDARLGVYAIDTGTGREI-AYRDGERFPYASTFKALAAGAVLREER ---LSGMERVVRYTKDELVDPSPVTEKHVDTGMTLDALADAAVRHSDNTAGNLLFEELGGP -KGLQAVLRSLGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDAWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SDREARPDNRLIARAASVVAE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013EE3F4B -----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFALDDPRDTTTPAAIAATLRRLVLGDALKPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVMWPVGGSPWIVTAYLQA -GAISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium holsaticum TaxID=152142 RepID=A0A1E3RVX9_9MYCO ----IQDQIAALEHQHGALIGVFAVNLASGNTV-AHRAQERFAMCSTFKAYAAARVLQMAE -HGELSLEERVFVDPDDIVANSPVTEARAGGEASLAELCRAALQRSDNTAANLLLTRIGGP -QAITAFARSIGDPQSRLDRWETELNSAIPGDLRDTSTPEALGGGYRNLLAGDVLAPPQRS -QLEDWMRANQT--SSMRAGLPQGWTSADKTGSGDYGSTNDVGIAYGPDGQRILLALMTRS -QASDAAGLRPLIGEVARLVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1824 TaxID=1463889 RepID=UPI00099BD3F1 ----AARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTVGAAAVLRDLD -RDGEFLARRIRYTAQYVEANSPITGRNLSRGMTVADLCAYSITHSDNTAANLLLRELGGP -GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRETDTTTPRAVGRTYARLVLGDALVPCDRR -LLTGWLLANTTSGERFRAGLPADWTVADKTGGGSYGGNNDAGIAWPPGRPPVVLAVMTTK -PDRDAPADNPLVARTAGVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. lig30 TaxID=1192124 RepID=A0A063BBE2_9BURK ---AAQTALAALEQASNGRLGVVALDTATGARI-AHRPRERFPMCGTFAVVVAAALLARAA -LDPSLMSRRVLYRRYDMVPESPVTKNRVDAGMTTEELCAAALQYGDRSAANLLLDLLGGP -RSATAFAHSIGDTAFRLDRWEPELNAATPGDERDTTTPLAMAGTLRRLLVGDALGAAQRA -QLKTWMLGNTMGAAGIRAGVPPDWQVADTTGAGDYGTTNGVAVAWPPSRAPLALAIYFTQ -PGGDARARDDVVAAAVRIVAEVf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 4(2017) TaxID=1404402 RepID=UPI0014087D58 -------ELESYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQRAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKNKVPILIAAYTQG -GRPNAAQIEAVFARVGRMVAE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C161610 -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISYEQQAVVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB78_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISYEQQAVVLAQVGRIA---- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A3D9IYT3_9ACTN ------TELRDLERRYGARLGVYARNARTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG --DCAPLDRVVHYPPRDILANSPKTEEHLSTGMPVGDLCAAAIQYSDNAAGNLLLRQIGGP -DGLTRFFRSLGDGVSRLDRWEPDLNTAVPGDPRDTTTAEALGRGFERLTLGRALDEAGRA -LLVAWLKGNTTSARRFRAGLPQGWVIGDKTGTGDYATAHDLGVAWTTRNTPILLTVLSAK -AAKDAPVDEALIAEAARVLA--- ->[subseq from] Beta-lactamase IMI-3 n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0P0G279_9BACT ------DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_007 TaxID=1898735 RepID=UPI0009F31BB5 ---ATARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR -VLRDAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR -ADAAAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SBT349 TaxID=1580539 RepID=UPI00066D16F8 ---STDRAFGELEREFDARLGVYALDTGTGREV-AHQADERFAYASTFKALAVGALLQEYG ---LDGIEEVITYASDELIDNSPVTENFVETGMSLRELCAATLWYSDNTAANLLFEALGGP -DGLEAALEELGDDVTEMDRYEPELSEGTPGDIRDTSTPRAMAGSLRAFLLGDALERDERE -LLRQWMVTNTTGETLINAGVPDGWTVADKSGTAGYGGRNDIAVVWPDDGDPIVMAVMSSR -DEQGAERRDELIAEAATAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium canariense TaxID=255045 RepID=UPI000A198F00 ---DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTASRLDHNEPELNRSPLGDPRDTTTPAAMAGNLRRLLTGEALSATSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIATYTQG -GTPSAAQIEAVFARIGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. LM091 TaxID=1904944 RepID=A0A1D8Y7V7_9GAMM -----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAE -QGRLSLDQRIPVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPEVNRFTPGDPRDTTSPAAMAASLQRFVLGDVLKPASRQ -QLADWLIDNETGDARLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-18 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A3Q9WYR0_ENTCL -------DIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKRSQ -DNQLSLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTIALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -YEKEAKHEDKVIAEASRIAID-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_006 TaxID=2175642 RepID=A0A2W1PWX2_9MICO ---ATARAFAALERRYDARLGIAAVDTGSGRTI-VHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVCELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] Beta-lactamase IMI-8 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A0A7ERS0_ENTCL ----AMDEIKKLETGFGGRVGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKGSQ -DNQLNINEIVNYNKRSLEPHSPITQKYKENGMSLGDMAAAALQYSDNGAANIILERIGGP -EGMTNFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVGKSLKNLALGNILNDHEKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGTCGYGTANDYAVVWPKNRAPLIISVYTTK -SEKEAKHDEKVIEEASRIAITH- ->[subseq from] class A beta-lactamase n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI00071BFE15 ---TLAQRLAGIERRTGGRLGVTLLD-GSGAVLgGQRQDERFPMCSTFKFVLAAAVLQRVD -RGELSLQRPVQIRAVDMLSHAPVTERHVGGALSVAELCRATMIFSDNPAANLLFPLVGDP -PGLTRFLRELGDPVTRSDRHEPEMNLFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] Uncharacterized protein n=1 Tax=Chromobacterium sp. Panama TaxID=2161826 RepID=A0A2T5NIC2_9NEIS -----ARQLAELERNAGGRIGVFAQEADSGRTL-AYRADERFPMCSTFTLLLVGALLQRSA -TQPDLLYRHVGYRREQLIDYSPIAEQYVEQGMSVKDLCDAAMRFGDNTAANLLLEQLGGP -QEVTRFARSLGDGLSRLDRVEPELNRAEPDDPRDTTTPAAMTANLRALLFSPLLPERQRG -LLNDWLLGNTTGNLRIRAGLPAEWRVGDKTGSGGHGAANNVAVAWRPGKSPLLLSVYYWG -STAMMDERNAVIAAVARVAAAEf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces neyagawaensis TaxID=42238 RepID=UPI0006E43496 --------LRALEEQYGARLGVYAHNVRTGETI-RHRADTLFPICSLFKTLAAAAVLRDLD -RDGEVLARRIHYTAADLLENSDVTRDHLATGMTIAELCDATIRHSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSGEPWRITDTTSPRAIGRTYARLVLGDALTRPDRA -LLTHWLLHNETSKTRMRAGLPSSWAVADKTGGGSYGTNNNVGIAWTEDGTPLVFSLMSRK -FDQDAATENKLIADTAHLLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD7BCC0 -----EAQLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIHYKKSDLIDYSPATEPNAGENMTVGELCAAAVTLSDNTAANLLLASFGDP -GAITTFCRSIGDEITRLDRTEPTLNYDTPNDERDTTTASAMLENLQRLLFTNVLTPASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGHGNANDIAVLWPTKRAPIIVTAYCEI -PAIAADERNAIIGEIGRIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Kalamiella piersonii TaxID=2364647 RepID=A0A3A9IPK2_9GAMM ----LATVAKQEEQALKARIGIAVIDTATGSVA-RYRGDERFPLNSTHKALLCGALLSQQD -KGRLMLSERTQFDRAALVTWSPVTEKSVAPAMSWQQLCHAAIAYSDNTAANLIAKKLGGQ -AAVTRFFADLGDKVTRLDRFEPELNSAIPGDMRDTTTPVAVSETLQKLTLGEALKPASRA -QLVQWMRDDRVAGALLRSVLPAGWSIADKTGAGEYGSRSIISVVWSENGKPVIIAIYVTQ -TEATLAQSNAAIARIGKAIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf117 TaxID=1736260 RepID=UPI0006F62456 ------AALEQIARDLGGRVGVTVLDTGGGPSL-QLAADAAFPLCSTFKLLLAAAILARVE -AGQDQLDRRIAYTAADLDVYAPITGGALKEGMSVAALCAAAMVWSDNTAANLLLEALGGP -AALTAYCRSLGDSVTRLDRTEPDLNSAEPGDPRDTTRPAAMAATVRTILLGDALTPGSRA -RLEGWMTAARTGTMRLRAGLPGDWGVGDKTGSGAYGTANVVAILRPPARPPLIAALYLTG -STASAEARDAAHAAIGRVIATAy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Actinopolyspora TaxID=2639451 RepID=UPI0013F67952 ---EAKDRFAGLEQRFDARLGVYAVDTATGEEV-THRADERFAHASTYKALSAGVVLRRNS ---IGGLNRRIHYSRSDLVTYSPITKKHVDTGMTLRAVLDAAIRYSDNTAANLLFREIGGP -AALQAALRGIGDTTIHVDRTEPELNRRAPDDIRDTSTPRAMAETLWKFTVGDVLAPDKRA -ILNEMLRTAKLTGDLVRAGVPSGWEVGDKSGAAEYGTRNDIAVIRPPGRAPIVLAVMSDR -QSRDAEYDDALIAQAARQVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Nitrincola sp. A-D6 TaxID=1545442 RepID=A0A099PGZ6_9GAMM ----LLSELKRIENHLDARIGFAAHDTETGMRW-EYNADQRFPLSSTFKTLACATLLQRVD -AGSEQLTTSVSVSSSDLVTYSPVLEEYADTRITLFELCEATMTTSDNTAANLILQRLGGP -ESVTDFARQLGDSVTRLDRWETDLNQAIPGDERDTTTPNAMVSNLEQLLSDKVLSLESKQ -YLQTWLVNNKVADGLFRSSMPGDWVIGDRTGAGGFGSRSITAVIWPAEREPVFVAFYITE -TTASFEERNAAIAQLGRVLI--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia jejuensis TaxID=328049 RepID=UPI00082FCA5F ----AEARLRQLEQEHDARLGVFAVDTGTGKTL-AYRGDERVGIGSTFKGVACAALLREHP -LSTGYFDQVVHFTKADLVANSPISETRVDAGMNVLELCNAAITVSDNTAGNQLLKLLGGP -EALTAFFRSIGDQVSRLDRWEPDLNANVPGDERDTTTAAALAADYRAFVVGDLLAAPEKG -QITSWLLANTTGGARIRAGLPADWKTADKTGTGDYGVANDIAITWPADGAPVVIGVLSTK -STKDAQADNPLVAAAAKVAVD-- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UIS5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIV------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces kaniharaensis TaxID=212423 RepID=UPI001295CD6B -----TASFNELEQRFGARLGVYALDTGSGREI-VHRADERFAFASTSKALATGALLRHAS ---DEQLDKVVAFRTEDLLKWAPITSQHVATGMRVRDLASAAIEYSDNTAANLVTAELGGP -AAIQQALRDLGDATTNVNRTEPTLNEATPGDPRDTSTPRVLAADLRRYVLGDVLADDRRR -LLTDWLVANTTGGPYIRAGLPADWKVGDKTGNAGYGTRNDIAVVWPSGGSPLVIVVLSDR -GKPDATSDDALIAQATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=UPI00105B8F26 ---DLTSRFTEIERRYQGRLGVYVPASGAIPAI-AYRADERFALCSTFKAPLVAAVLHQYP ---LSYLDQRVTFSKADISSPSPIAEQHIDTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP -AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRA -MLTDWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGVPHVVAIYTDI -AGYDAQPNDTFVADAARIVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. JB150 TaxID=2714844 RepID=UPI0014099286 -----TGRLRDLERHYGAKLGVYARNLRTGRTV-RHHADDLFPICSVFKTLAAAAVLRDLD -RDGEFLARRIHYTEADLVDGSDKTREHLAEGMTVAELCDVTIRFSDNAAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE -LLTHWLLHNTTSGDRLRAGVPPTWTVADKTGGGAYGTNNNVGIAWTPDGTPVVLAVLSRK -FDPAAVRDNALIAQTAAVL---- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella genomosp. 7 TaxID=1416805 RepID=A0A261RJD8_9BORD ---TVAETAARVEARLGGRVGVALQRLGEPAVA-LYRADERFPMASTFKALACGALLAKVD -AAEQSLDTVVLYGPETLVPYSPVTAQHVGKGMTLAQLCHATITLSDNTAGNLVLRRIGGP -AGLTAFLRSTGDEMSRLDRWEPELNEALPADPRDTTTPRAAAGTLGRLLFQGVLSPGSSH -QLEAWMIADQVADELIRASLPQGWGIGDKTGSGERGSRSIIAVIRPPHGKPWLASIYLTG -SSSRPQERNAAVAEIGRSMI--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C152992 -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTSANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGTPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Sge12 TaxID=1972846 RepID=A0A1V0QUX0_9ACTN ----VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD -HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLVLSILSTL -PEPTAPRDNTLIARTAKLLAD-- ->[subseq from] Clavulanic-acid inhibited carbapenemase IMI-2 n=12 Tax=Enterobacteriaceae TaxID=543 RepID=G9HXF8_ECOLX ------DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFYSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBP8_STEMA -----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR -RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ -QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPMGGAPWVITAYLQA -ADIRNDQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium bourgelatii TaxID=1273442 RepID=UPI0013D33463 --qDLSARFAELERRYESRLGVHVLADGDAAPI-SYRADERFAFCSTFKAPLAAAVLQRNP ---LTFLDKVITYTRDDIRSTSPITEQHVDGGMTIGQLCDAAVRYSDGTAANLLLAEIGGP -AGFTQFLRSLGDSVSRLDQLEPELNRDAPNDERDTTTPRAIAGVFQRLVLGDALPADKRG -LLTDWMVRNTTGDKRIRTGFPPDWKIADKTGSGDYGRTNDVAVVWSPSGASYVVAIYSDC -VTYDAPFNDAIVAAAATIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Moraxella sp. RCAD0137 TaxID=1775913 RepID=A0A2K0XQC1_9GAMM ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNTATNLLLKELGGV -EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. adm13(2018) TaxID=2479007 RepID=A0A652L7B1_9ACTN ----LLARLRALEERHAARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTFAVAAVLRDLD -RDGSFLARRLRYTADDVTRWSPVTERNIAHGMTVSELCDATLRFSDNTAANLLLRELGGP -TSVTRFARSIGDRTTRLDRWEPELNSAEPWRETDTSTPRAVGRSYGRLLLGAALPRDDRE -RLTTWMLANTTSTERFRKGLPADWLLADKTGGGRYGGNNDAGVAWKPDGGPVVLTVLSTR -FTEDAAPVDALVADAAALVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 3212.4 TaxID=2135786 RepID=A0A495H540_9ACTN ------TELRDLERRYGARLGVYARNARTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG --DCAPLDRVVHYPPRDILANSPKTEEHLSTGMPVGDLCAAAIQYSDNAAGNLLLRQIGGP -DGLTRFFRSLGDGVSRLDRWEPDLNTAVPGDPRDTTTAEALGRGFERLTLGRALDEAGRA -LLVAWLKGNTTSARRFRAGLPQGWVIGDKTGTGDYATAHDLGVAWTTRNTPILLTVLSAK -AAKDAPMDEALIAEAARVLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonadaceae bacterium NML93-0399 TaxID=2032565 RepID=A0A2A3LNG3_9GAMM -------VFAALERAAGGRLGVALLDTGTGRRV-GWRDEARFPMCSSFKWLLAAAVLHAVD -RGAIGLRQAVAVHADDIIAHSPYVQTRVDGGATVSDLCRATVIESDNAAANLLLPLIGGP -AGLTAFLRGNGDPVTRLDRNEPTLNEAAAGDPRDTTSPRAMVDDLHRLLLGDSLRAPSRA -MLTAWLVDNRTGDARIRAGVPAGWIVGDKTGTCGAGTAADVAVLYPPDRAPLLLAVYVHG -ASISGPAMDALHADVARAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0009DFE4D4 -----RADFERLERAFGARLGVYAVDTATGREV-AYRADERFAYASTHKVFTAGGVLQRTP ---VAELDRTVTYSPQDVVTGSPVTEKHVGTGMPLRAVMDATLRYSDNTGGNLLFRELGGP -AGLTAVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVGLRAFALGDALPEDKRK -ILVDIMRGNTTGDANIRAGVP-GWPVADKTGTASYGTRNDIAVVWPPNRAPIVLSVLTDR -SAKDAKIDNALLAQATVATV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 3211 TaxID=1964449 RepID=UPI0009A4ACA1 ----VVARLRELEREYGARLGVYARDTATGRTV-VHRADELFPMCSVFKTLAVAAVLRDLD -HGGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLSILSTL -PEPTAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase IMI-3 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=D0V475_ENTCL ------DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] Beta-lactamase IMI-3 n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A0M3STF3_RAOOR ------DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-17 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A2D3E5L4_ENTCL ------DEIKNLETDFNGRVGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI001261608F -----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGRLSLDRRVAVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGMVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ -QLADWLIDNETGDTRLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAVI----- ->[subseq from] class A beta-lactamase n=1 Tax=Asticcacaulis biprosthecium TaxID=76891 RepID=UPI00068276C9 ------TAMLDITKRHGGRIGVSAIDAGSGARL-SVSAQDRFGMMSVFKWILAAAVLARVD -KGELKLDQVVRYSAKDLIAYSPVTEKEVKDGMAVGELCAATVSKSDNTAANLLLPLVGGP -EGLTKWIRSLGDAVTRCDRKEPELNVVAEGDPRDTTTPEAMTQLLQIVFSGAALEADSIK -QLRDWMEATSTGDKRIRAGVPSGWTVGNKTGTAN-GAVNDVAVIWPKSEGPIFLSIFTTG -GALEADAKEQVVADIARLVCEVf ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BA24DCF ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. RV15 TaxID=909626 RepID=A0A101V4G5_9ACTN -----AARLRELEAQHSARLGVFAYNAATRRTV-RHRADELFPMCSVFKTLASAVVLRDLD -RHGEFLSHRIHYTEADLPEGSDQTRKHLADGMTVAELCEVAITYSDNGAANLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPYAIARTYGRLVLGDALPRHDRD -LLTHWLLNNTTSGRRFRAGLPTSWTLADKTGSGSYGTANDVGVTWTDTGTPLVLAVLSTR -PDQDAAWDDALVAETAAVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sp. XM4083 TaxID=2583238 RepID=A0A505H6N4_9MICO ---AADSAFTQLEDDFDARVGVYAVDLDTGREI-AWRADERFAYASTIKAMASAALLDEVG ---TDGLSKDIAVDEDDLVSHSPVTETNVGGTMTLAELCEAAMTQSDNGAANLIVAELGGP -ASLDSRLDDLGDTGTTVSRIEPGLNEATPGDPRDTTTPRASASNLRKYVFGGVLSDDEAT -TLTDWMKATQTGDTLIRADLPEEWTVGDKSGTGSYGSRNDLGIIWPDDGGPIVISVLSSK -KEKDAEADDRLIARAAASAVD-- ->[subseq from] Class A beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=A0A5P2BGQ1_STRVZ ---RLAPRFDAIERKHGGRLGVYALATGTGATL-AHRADDRFAFCSTFKALAAAAVLDRHP ---LRHLDKRVTYTAADVDSISPVTEKRIATGMTVGELCDAAIRYSDGTAGNLLMRQIGGP -AGLTAYLRGLGDEVSRMDDYEPELNDVPPKDPRDTTTPRAVAADYRALVLGDALPAAKRA -LLAGWLGRNATGARRIRAGVPKGWRVADKTGTGDWGRANDIAVLRPPDADPLVLAVMTDR -PGRDTPPVDAFIAEAAELVVA-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IJX5_9ZZZZ -----------------------------------------FPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Lentibacillus jeotgali TaxID=558169 RepID=UPI00026267CD ------EKFVQLENEFDAQISVYAMDTGTKQTI-EYRPNERFAYSSTFKPLAAAILLKQNN ---IENLEKVVTYTNDDLVTYSPVTEKHVDAGLTLLEISEAAIRKSDNTAGNLLLEAIGGP -DKFEHALRDIGDDVTQPERYETELNEFTPGNKRDTSTPRAMATNLKKVALGDFLPGDKRE -LLIDWMTGNESGDPLIRAGAPEKWTVVDKSGAGTYGTRNDIAVVWPPNKEPIVIAIMSRH -DTENAEYDDALIAKAAEITLNAf ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-15 n=1 Tax=Enterobacter cloacae subsp. cloacae TaxID=336306 RepID=A0A1S6QNP3_ENTCL ------DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -TKKEAKHEDKVIAEASRIAID-- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009BF9EA8 ---TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. 1.19 TaxID=1925589 RepID=UPI000948C5CD -----QQVAQQVEAQLPGRVGYAELDLASGQLLsGWRAQARFPLNSTFKVLLCAAVLARVD -AGQEQLARRIRYLPGDLVAWSPVTERHLADGMRVDALCHAAITVSDNTAANLLLNTLGGP -SALTAFLRRIGDTETRLDRWEPALNSAEPGDVRDTTTPERLARTLRRLIDGNTLSAASRQ -QLLAWMEADSVGGPLLRSVLPPGWYIADKTGAGEHGSRGIVALLGPGGTPTRIVVIFLTD -NPASLDVRNQHIARLGASLIAHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. NRRL WC-3618 TaxID=1519490 RepID=A0A0N0T8Z5_9ACTN ---EVTARLHTLETQHGARVGVFAHNLATKQTI-RHRADERFPICSLFKTLAAAAVLRDLD -RSGEVLSKRVHYTADDLVDGSKQTEEHLAEGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAITRFARSVGDRATRLDRWETELNSAEPWRRTDTTTPYAIGRTYARLVLGDVLNRPDRE -LLTHWLLTNTTSGNRFRLALPPTWTIADKTGAGSYGTNNNVGVAWTQDGTPLVLAVQTTK -PDQDAAADHPLVAETAAVLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. URHA0013 TaxID=1380352 RepID=UPI00047F83EF ---DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVARQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLLTGEALSATSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDVAVAWPKPDAPILIAAYTQG -GTPTAAQIETVFARIGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A3N1KGQ2_9GAMM -----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGRLSLDQRVAVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGVVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ -QLADWLIDNETGDTRLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAV------ ->[subseq from] Beta-lactamase n=1 Tax=Umezawaea tangerina TaxID=84725 RepID=A0A2T0TGX3_9PSEU ---TATADLTALEAGLGGRIGVHAVDTGTGTTV-AHRADERFLMCSTHKALVAAAVLRTGV -----DLDRLVRYDESELLSYAPVTSQHVADGMTVAALCEAAITRSDNTADNLLLEILGGP -QAVTAFVRTLGDDVTRLDRVEPDLNVGAPGDERDTSTPARMVADLRELVLDDGLDPAGRD -RLTGWLTANTTGDDLIRAGLPAGWRVGDKTGSGAAGEVNDIAVVWPPGRAPWVVAVYAVP -TDPKSTAVRAAVASASRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Kribbella flavida TaxID=182640 RepID=UPI00059E88F5 --------FGKLEKKYGARLGVYAVDTGSGREI-AHRADERFAYASTFKALAAGAVLRKYT ---LQGMGKVVKYSESDLLANSPITEKHVATGMTLRELCDAAVRYSDNTASNLLFDALGGP -KGLDAVLAELGDNVTQMEQRELELSVWDPSNPRDTSTPRAFARNLRTFVLGDALRAPERA -QLTTWLRTNLTGAELIRAGMPKGWVVGDKTGTATYGGRNDIAVVWPPGRAPIVLAIFSNR -PAAEAEHDNRLLAEAARVVAAAy ->[subseq from] Class A beta-lactamase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=A0A6A7ZSQ1_RHIML --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSRFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLERFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces odonnellii TaxID=1417980 RepID=UPI0006269039 -----HDRLIELERKFEARLGVYALATGTGEGI-AHRADERFAFCSTFKGVAAAAVLHHNP ---LSHLDTVVRYTDDDLMKHAPITSQNVAKGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP -AGLTAYTRTLGDTVTRINRTEPAISEAVPGDPRDTTSPRAFGTNYQKFVLGNALPGEKRA -FLRDLLERNTTGAERIRAGVPRGWTVADKTGTGSYGTLNDMAIVWPPKSPPLVIAVMSTK -AGKDAEYDQSLIAEAAAYAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=A0A0L8QEL8_9ACTN ------HTLKGLEGKYDAKLGVYAVDTGSGREV-TYNDGERFAYNSTFKALAAGALLRKYS ---LSGMDRLITYSKDDLIADSPVSEKHVDSGMKLGELCDAAIRFSDNTAANLMFDELGGP -KALNAELKKIGDDVIRMERREPQLSRWVPGETRDTSTPRAMAADLRAFVLGDVLHKEERA -QLTTWLRTNKTGDELIRAGTPKSWVVGDKTGTGSYGARNDIAVLWPPHKAPIVVAILSHR -NKKDAKFDNKLIAETAKVVT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Aquabacterium sp. TaxID=1872578 RepID=A0A5C8BCH3_9BURK ---QMTAALQQLEAKAQGRLGVHVIDTANGHEF-GYRSDETFMMLSSFKLLASALVLARVD -RGQESLERRIRYRKQDLVPWSPVTEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP -KALTQFARKVGDKVTRLDRIEPDLNIRVEGATLDTTSPRAMAMTMNKLLVGDALSPTSRK -LLRQWLLENTTGGKRLQAGVPADWTVGDKTGTNKT-DANDIGILLPPQGAPVFVTAYLSD -SPATSQIKEETLAKVGRLAA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0008F4D052 ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGTVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C5BDD0 -----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia jiangxiensis TaxID=282685 RepID=UPI000303516E ---ALSGRFGELEGRFGARLGVFALDTGSGHIV-EYRADERFAFCSTFKALEAGAILTTAG ---PAELDRRITYTATDLTAYAPITRPHVTDGMTVRDLLDAAVRYSDNTAANLLFGLLGGP -AGLQHDLRNLGDQVTRSDRLEPALSEATPGDPRDTSTPRTFATDLRTYVLGTALPTDNRT -LLTTMLRTNTTGAGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPIVLAVMSTR -HGHDDTYDNALIAQAANAAVT-- ->[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA5B00A ------AVFKALEEEYAARLGVFALDTGTGQTV-SYRADERFTYASAHKPLAVGVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFDEIGGP -EGFKEGLRAMGDTVTEPERIEPELNNVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-16 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A218MJA7_ENTCL -------DIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKRSQ -DNQLSLNQIVNYNTRTLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTIALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -YEKEAKHEDKVIAEASRIAID-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. WAC05950 TaxID=2487419 RepID=A0A3R9WN53_9ACTN -----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTTGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=[Pseudomonas] geniculata TaxID=86188 RepID=UPI00070C0BA3 ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGTVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA4F40B ------AVFKALEEEYAARLGVFALDTGTGQTV-SYRADERFTYASAHKPLAVGVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFDEIGGP -EGFKEGLRAIGDTVTEPERIEPELNNVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia hydrocarbonoxydans TaxID=76726 RepID=A0A4Y3WNF1_9PSEU -------DLAALEGRFGGRIGVHALDTGTGATV-THRGGERFLMASTAKLPLAAAVLDRAV -TDPALLDRLVRYGPGALLEYAPVTTANVATGMTVADLCDAALTVSDNTAANLLLDLLGGP -AAVTAFVRGLGDPTSRFDRTEPDLNSTGPRDERDTTTPAAIVATVRAVSLGDALPPAARD -RLTTWLVANTTGDTAIRAGVPGGWVVGDKTGTGAQGERNDIGIVRPPDRAPLVLAVYTDP -DVADATAGDATVAEATAIAVR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A2M9H4U4_9BURK ---TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWRIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. SID8385 TaxID=2690364 RepID=UPI001361818B ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELSEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Shinella sp. 65-6 TaxID=1895831 RepID=A0A1M3CAB0_9RHIZ --eALEGRLAELEGRHKGRIGVAIHNLATGARL-GHRADERFLMCSTFKALLAGYVLARVD -RKEEALDRRIVVKKADLLDWSPVVEKHVGKAISVARLCEATITLSDSAAANLLLAGSGGP -EAVTRFLRGLGDAVTRLDRTEPALNYETADDERDTTTPIAMAETLRRLVFSDVLSPSSRA -QLAAWLVMNKTGDTRLRAGFPAGWITGDKTGTNGHGNANDVAVAWSPDRGAIVVTAFCEI -PGISGDARNAVIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193BYN4_AMYOR ------AGFERLERAFGARLGVYAVDTATGREV-AYRADERFAYASTHKVFTAGGVLQRTP ---VAELDRTVTYSRQDVVANSPITEKHVGTGMPLRAVMDATLRYSDNTGGNLLFRELGGP -AGLTAVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDIMRGNTTGDANIRAGVP-GWAVADKTGTASYGTRNDIAVVWPPNRAPIVLSVLTDR -STKDAQIDNALLAQATVATV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. YIM 121038 TaxID=2136401 RepID=A0A5B7ULA7_9ACTN ----YARAFKKLERKFDARLGVYAVDTGTGREV-AYHDGRRFAYNSTFKALAAGETLRSYA ---PDKMDQVVKYSKDDLVTYSPITEKHVDTGMTLRALCDAAVRYSDNTAANLLFDKLGGP -KGLDAALERIGDDVTRMERVEPLLSRWVPGEKRDTSTARALAKDLRAYVLGDVLAGPERA -QLATWLKTNTTGDHVIKAGVPKNWVVGDKTGTGSYGARNDIAVVWRPDAAPLVVAILSHR -GDKDAAPDDKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DED5A2 ---EASTRFSSLERKYDARLGVYALATGTGASL-GYREDERFAFCSTFKTLAAAAVLQRNP ---LSHLNKVITYDKNEVNSISPITERHIGTGMTIRQLCDAAIRYSDGTAGNLLMRDIGGP -GQLTHYLRGLGDTASRMDQYEPELNRDPPGDPRDTTTPRSIAHDYRKIVLDDALPPEKRA -LIKDWLQRNTTGAQSIRAGVPHGWGVADKTGHGDYGRANDIAIVTPPGRNPLVIAILSDR -AGYTAEARYPIIAEAAKYVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces bauhiniae TaxID=2340725 RepID=A0A4Z1D9F1_9ACTN ----LRPELAALEKRYGARLGVYAHNTRTGATV-AYRADESFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPADILANSEQTKAHQETGMALGEVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSGGDRE -QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTPLLLSVLSTK -PTPDAPVDEALIEETARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 3058 TaxID=2561921 RepID=A0A4Z1CTJ6_9RHOB ---TVTEAARAIEADLGGRIGVSLRQPGGAGAT-GYREDERFPLSSTFKAPLCGAILTLVD -AGEDQLDRRIGYSSGDLVTYSPVTEAR--DAMTVVELCEATITLSDNTAANLLLDRLGGP -EDFTEYLRAIGDDTTRLDRWETDLNAAVPGDPRDTSTPAAMTATLETLLFGPVLSDAAQQ -QLEAWMRANQVADDLIRASLPEGWIIGDKTGAGGYGSRSIVAVIRTPQGDPWLASVYLTG -SEADMPTRNRAIARVGAAIVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Prauserella marina TaxID=530584 RepID=UPI000B8099A3 -----HDRLHELERDYGARLGVYALATGSGAVV-EHRADERFAFCSTFKGLAAAAVLQRNP ---SSHVDTVLTFTEADLLSSSFVTREHVASGMTIGQLCDAAVRYSDGTAGNLLVRDLGGP -GEFTAFLREIGDEVTRMDRPEPELTEAKPGDPRDTTSPRAIGTDYQGIVLGDVLPEDKRG -FLRDLLERNTTGDERIRAGVPEGWTVADKTGTGSYGTMNDIGIGWPPSGEPLVIAIMSSK -ADPDSDYDQKLIADATEYVVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus kimchii TaxID=746691 RepID=UPI00034BDC71 -----SEAFKKLEDEFDVKLGVYAIDTGSNKEI-NYQENDRFAYASTFKPLAVGAILQTKS ---DPELQEVIRYTEEDLVTYSPITEKHVDEGMTLLEISDAAIRYSDNTAANLLLEAIGGP -DELETKLRDIGDEIIEVDRYETELNEATPGDIRDTSTPKAMANSLQQYVLEDVLDADRRE -ILTNMLINNTTGDALIRAGVPEGWTVGDKTGAGGYGTRNDIGIIWPEDNEPIVIAIMSSR -DVEDADYDDKLIEKATKVVVKE- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-12 n=2 Tax=Enterobacter cloacae complex TaxID=354276 RepID=A0A173GTS2_ENTAS ------DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHDDKVIAEASRIAID-- ->[subseq from] Class A beta-lactamase n=1 Tax=Azonexus hydrophilus TaxID=418702 RepID=A0A1R1I8N1_9RHOO ---HLRSRWRELEQQGGGRLGVHLLDTATGAEY-GYRQDERFMLLSSFKQLASALVLQRVD -TGREALDRRIVYDRSVLLPWSPVTEQHADGQMTLAALCEAAITTSDNAAANLILASYGGP -AALTAWLRQLGDGVTRLDRNEPELNTKHSQGELDTTSPRAMTQTMQKLLLGDVLSPASRT -ILQRWLLANTTGGRRLKAGLPTDWRIGDKTGTNRS-DANDVGIVWPAGGKPLLVSAYLAD -STAAPAAREACLAGVGRLLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS80.1 TaxID=1680159 RepID=A0A1Q5R357_9BRAD -------ELASYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLASMIPYGQADLLSHAPAAKQNLATGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPQDTTTPAAMAGNLRRLVLGESLSPASRT -QLTDWMVNCKTGANRLRGGLPISWKIGDKTGNNGKDASGDIAVAWPKNKTPILIAAYTQG -GTPNAAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia (strain R551-3) TaxID=391008 RepID=B4ST44_STRM5 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIGVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Franconibacter helveticus TaxID=357240 RepID=UPI000405F8A6 ---ALTAAAQQEEKTLNARIGVTVLDTVTGKTL-SYRGDERFPLNSTHKPLLCGALLKQAQ -EKKIRLTDSVLFDKSQLVDYSPVTEKHVSPQMNWLQLCSAAVSYSDNTAANLISQKAGGP -QAITAFVRASGDNITRLDRFEPELNEARPGDERDTTTPDAISHTLQKLLLGDVLSEASRQ -QLTRWMAEDKVADALLRKSLPKGWKIADKTGAGGYGSRSIISMVWPEKGAPMVVAIYITL -TEASLAQSNDAIARLGGVIF--- ->[subseq from] Beta-lactamase n=1 Tax=Prauserella marina TaxID=530584 RepID=A0A222VNQ1_9PSEU -----HDRLHELERDYGARLGVYALATGSGAVV-EHRADERFAFCSTFKGLAAAAVLQRNP ---SSHVDTVLTFTEADLLSSSFVTREHVASGMTIGQLCDAAVRYSDGTAGNLLVRDLGGP -GEFTAFLREIGDEVTRMDRPEPELTEAKPGDPRDTTSPRAIGTDYQGIVLGDVLPEDKRG -FLRDLLERNTTGDERIRAGVPEGWTVADKTGTGSYGTMNDIGIGWPPSGEPLVIAIMSSK -ADPDSDYDQKLIADATEYVVT-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0006AED99F -----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces spongiae TaxID=565072 RepID=A0A5N8XNI1_9ACTN -----NGELKELERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTHKALSAGAVLRKYG ---LNGMNEVIKYSEDDLVHHSPVTEKHVETGMTLSELCDAAVRFSDNTAANLLFDALGGP -KGLQAELRKLGDKVTLMERVEPGLSDWVPGETRDTTTPRALAKDLRAYVLGDVLRGPERD -RLTTWLKTNTTGDEVIRAGVPDGWVVGDKTGSGGYGARNDIAVVWPPDSAPIVMAILTNR -GEADDTYDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CG 926 TaxID=1882405 RepID=A0A2V2B2V8_9ACTN --------LRALEREYGARLGVYALDTATGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD -HDGAHLAKRIHYTPQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNTAGNLLLRELDGP -TAITRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLTIGDALDSGDRE -RLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPMVLAILSTM -PEATAPRDNTLIARTAKLLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDFEA7B -----EERLAALESKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIRYSEGDIIGGSPATKLRVGDGMTVAELCAAAVALSDNAAANLLLASFGGP -KALTAFCRSLGDDLTRFDRTEPTLNYDTPDDQRDTTTAAAMLENLRRLLFTDVLTAASRS -QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWPSKRAPIIVTAYCEI -PSISADERNAVIAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_039 TaxID=2175624 RepID=A0A2W1TYK6_9MICO ---ATARAFAALERRYDARLGVVAVDTGDGRTI-EHRAGERFAFASTNKVFIAAAVLDASS ---DADLATVVHCDRGDLLEYAPVTSGYVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRVEPDLNEATPGDPRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAIVTPPGRAPIVLVVMTSR -ADPGAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Oleiagrimonas citrea TaxID=1665687 RepID=UPI001445A51D ----IHTRLAALEKRHGGRLGVAMLDTASGRQI-GYRADHRFLMCSTHKVLVVAALLARVD -RGIEDLQRRVIFDHQALLDYAPVTRRHVGAPMTLEALCEAAITLSDNTADNLLLNALGGP -DAVTAYARSLGDRVTLLTRTEPALNLALPDDPSDTTTPQAMLSDLRDLLIGEALHPASRQ -RLLGWMRACQTGSRLLRAGLPRAWRCADKTGRGAANEIHDIGLIEPPHGKPVLVCAYYAD -SIAPEAARESVLADVGRLAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea septica TaxID=472695 RepID=UPI000534DBE9 --------AQQEEQALKARIGIAVIDTGAESVA-SYRGDERFPLNSTHKALLCGALLSAQD -KGKLRLTERTQFDRTALVTYSPVTEKFVAPAMSWQQLCSAAISYSDNAAANLIAKKLGGP -IAVTRFFADLGDKVTRLDRSEPELNSAIPGDVRDTTTPLAVSETLRQLTLGEALTPASRA -QLLQWMRDDKVADALLRSVLPTGWSIADKTGAGEYGSRSIISVVWPQNGKPLIIAIYITQ -TEATLAQSNAAIARIGKAIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chilikensis TaxID=1194079 RepID=UPI0014093079 ------PRFRALEREFDARLGVYALDTGTGRSV-GHRADDRFAYASTFKALAAGAILRKYG ---TDGIDKVVTYSRNDVVANSPVSENFVGTGMSLRGLCAATLRYSDNTAVNLLLDELGGP -DGLEEVLEEFGDDVTEMDRYEPEMSDGTPGDIRDTSTPRAMAESLRAFLLGDALERDERE -LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGSAGYGGRNDIAVVWPEDGDPIVMAVMSTR -GKQGADRRDALIAKAATVAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. H036 TaxID=1519487 RepID=A0A0M8UDN8_9ACTN -----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTTGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sedi TaxID=555059 RepID=A0A5C4UU38_9ACTN ---EAAEEFEALEDEFDARLGVYALDTGSGGEI-AHRDDERFAYASTFKALLVGAVLDAHG ---TDGIEEVVDYTEDELVDYSPVTENFVDSGMSLSQLSAATLWYSDNTAANLLLDAVGGP -DGLQEALREMGDDTTEVSRYEPELNEATPGDTRDTSTPRAMADDLRALLLEDALGERERH -LLRQWMETNTTGGTLVEAGLPAEWTVADKSGSAGYGGRNDIAVVWPDDGDPIVLAVLSSR -DEEDAERDDALVARAATVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridochromogenes (strain DSM 40736 / JCM 4977 / BCRC 1201 / Tue 494) TaxID=591159 RepID=D9XGI8_STRVT ------------------GLGVYARNLRTGRTV-TYRAAERFPMASVFKTLAVAAVLRDLD -RDGEFLARRIHYTQDYVTEFSPVTEDHVATGMTVGELCDATIRFSDNTAGNLLLKELGGP -TAVTRFCRSVGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLTYARLVLGDVLEPRDRA -RLTDWLLRNTTSIDRFRKGLPADWLLADKTGGGQYGSNNDVGITWPPDGPPIVMSVLTTQ -PEEDAPADNPLVAETAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI001428685B ------GEFDALETEFDAHLGVFGIDTGSGRTV-EHRADERFAYASTSKALLAGVILATTA ---PADLELRIKYTSADLVANSPISEQHLADGITLREVLDAALRYSDNTAANHMFARLGGP -KGVERNLRALGDNVTQMDRTETALNEAIPGDTRDTSTPRALAADLRKYLLDSALTPEARA -ILTDMMRRNTTGGELIRAGVPADWQVADKTGSAAYGTRNDIAVLWPPNRAPIVLTVLSTR -AKQDASYDNALLAKAAKIAVQE- ->[subseq from] class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI0005ED6A56 ----YNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFDHIGGP -SGFKSALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKK -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGMRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQASKIVFDFf ->[subseq from] Beta-lactamase n=1 Tax=Murinocardiopsis flavida TaxID=645275 RepID=A0A2P8CF33_9ACTN ----ADREFKELEGEFDARLGVYAIDTGSDRTL-SYQEDERFAYCSTHKSLSVGAVLEQNS ---LKEMEKLITYTEEDLVAYSPITEKHVDEGMTLRAVSDAAVRYSDNTAANLLFEELGGT -NGFGDALKGIGDDVTDVSRIEPDLSEGTPGDVRDTSTPQQMATDLREYTLGDTLSTKKRA -ILTDLLVRNTTGDELIRAGVPDGWKVGDKTGSGGYGTRNDIAVIWPPEDDPIVLAIMSSR -DTKDAESDDKLIAESAEVAID-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia thermophila TaxID=1848 RepID=A0A1M6P9Y8_PSETH -------------ARRGVRLGVHAVATADGREL-AHRADERFAHCSIVKVLAAGAVLDRFP ---IEQLDRRLPVEAADLVAHSPSARAHVGTGMTLREAAEAALRYSDNTAGNLLLRAVGGP -EGITAFVRSLGDPVTRSDRWEPALNTAVPGDERDTSTPRALSADVRELVLGSRLDVAARE -LLRGWMLANTTGDARIRAGAPAGWRVADKTGTGGYGTAGDAAVLWPPQGAPIVLTVLTAG -DHPDAQPDEAVFAEVTRIVT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALA8_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADXRFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-S7GS2 TaxID=2202000 RepID=A0A2U8UZT0_9ACTN ----FASEFKKLERKYDARLGVYAVDTGNGREV-AYKDGERFSYNSTFKALAAGAVLRKHS ---PSAMNRVIKYSKDDLVATSPVSEKHVATGMSLSELCDAAVRYSDNTAANLLLEDLGGP -KRLEGVLKGIGDDVTRMERIEPKLSQWTPGDTRDTTTPRTLAKDLRAFVLGGVLDKGDRK -QLTKWLRTNTTGDEVIRAGMPKGWVVGDKTGAGTYGARDDIAVVWPPGRAPIAVAIMSNR -FKKDVDFDNKLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A498CGM0_9GAMM -----AKDFAALEVASGGRLGVTLLNTGTGWRT-GNRQDERFPMCSTFKFVLSAAVLHLAD -QGRLSLDRRVAVRQQDMLSHAPVTTRHIGKDVTVRDLCRATMITSDNPAANLLLGMVGGP -AGVTAFLRANGDAVTRNDRLEPEMNRFAPGDPRDTTSPAAMAASLQRFVLGDVLKPASKQ -QLADWLIDNETGDTRLRAGLSKAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ATVDDAGRNDVLRQVAV------ ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. AC27/96 TaxID=1841653 RepID=A0A1B9S3Y3_9RHIZ ----QQKRLAALESKYPGRICVSILDLASGRRV-DHRAGERMLICSTFKTLIAALVLTRVD -KGEEKFDRRIAYSKSDLVESSPATGAQLETGMTIAELCAAAMTLSDNTAANLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDKPDDQRDTTTAAAMLENLRRLLFSDLLSAASRS -QLAAWLMTNKTGDTRLRAGVPKGWLAGDKTGTNGDGNANDIAVLWPTNRAPIIVTAYCEI -PGISADARNSIIAEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. Leaf154 TaxID=1736277 RepID=A0A0Q5KAT0_9MICO ---ATARAFASLERRYDARLGVAAVDTCSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR -VLRDAMLGNTTGDATIRAGVAPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR -ADAAAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. 603 TaxID=2483798 RepID=UPI000F093356 -----AAELDALEERYAARLGVFAVDTGSGATV-EHRADERFAYASTHKALSAAAVLAGSG ---PDRLDDVVRYDASELVAHSPVTEQHVGTGLSLRRIAEAAVRESDNTAGNLLLEELGGP -AGFERTLEALGDDVTVAARRETALNEATPGDPRDTTTPRAFAQVLRAYAVDDALDTADRR -TLLRWMRGNATGDTLVEAGVPDGWRVADKSGAGGYGTRNDIAVVHPPGRSPIVVAVFSDR -GQPEADYDDDLIADAARAVI--- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013313D32 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKXX--- -----AFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=UPI000B4D9241 ---RLATVVKQEEQTLNARIGVAVIDTASDKMV-SYRGNERFPLNSTFKALLCGVLLSEVD -KGKVALTDAIQFDKTELVEYSPVSEKFVAPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP -VAMNLFFSGLGDSVTHLDRYEPELNSAIPGDERDTTTPVAVSQTLQKLTLGEVLKPSSRQ -QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKDSSPLIVAIYITQ -TEATIAQSNEAIARIGKIL---- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=A0A1H5RIJ1_9PSEU -----QADFTPLEREFDARLGVYAVDTGSGREL-LHRADERFGYASTHKAFSAAAVLQRTS ---VDGLAKVLKYTRADLQENSPVTEKHVETGISLRDAIDAALRYSDNTAANLLFRELGGP -PGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMATSLRAFTVGDALPPEKRQ -ILTDMMRANLTGAALIRAGAPEGWAVADKTGTGEYATRNDIAVVWPPGRAPIVLVVMSDK -KTEHADHDDRLIAAAAKLAF--- ->[subseq from] Beta-lactamase n=1 Tax=Oleiagrimonas sp. MCCC 1A03011 TaxID=1926883 RepID=A0A328T3H7_9GAMM ----IHTRLAALEKRHGGRLGVAMLDTASGRQI-GYRADHRFLMCSTHKVLVVAALLARVD -RGIEDLQRRVIFGHQALLDYAPVTRRHVGTPMTLEALCEAAITLSDNTADNLLLNALGGP -DAVTAYARSLGDRVTLLTRTEPALNLALPDDPSDTTTPQAMLSDLRDLLIGEALRPASRQ -RLLGWMRACQTGSRLLRAGLPRAWRCADKTGRGAANEIHDIGLIEPPHGKPVLVCAYYAG -SIAPEPARESVLADVGRLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhizobium multihospitium TaxID=410764 RepID=A0A1C3TZF4_9RHIZ -----EAQLAALDSKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIRYAKSDLVDGSPATKEHAGETMTIAELCAAAVTLSDNTAGNLLLASFGGP -EAITTFCRSMGDEITRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDVLTAASRS -QLAAWLITNKTGDVRLRAGLPKDWLVGDKTGTNGAGNANDIAVLWPANRAPILVTAYCEI -PEIAAGERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_052 TaxID=2175655 RepID=UPI000DA6F504 ---ATTRAFDGLEGAHDVRLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAS ---PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP -SVVQQWLRGTGDQVTQVVRIEPEFNEATPGDDRDTTTPAQFAADLRTVLLGDALQPDDRE -LLVDTMAGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR -STADAEPDDALVAAATRTAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JUb58 TaxID=2485114 RepID=A0A4R7FMV0_9BURK ---QFAKAMKALERSVGGRLGVSLLNTMTGQAL-GWRQDERFPMCSTFKMLLAGQVLSRVD -AGQEKLDAQVTFGRSALVEYSPVIEKFAGKAMSVEALCHAIVTISDNGATNLLLERVGGP -AGFTAYVRSLNDPTTRLDRIEPDMSESKPGDVRDTTSPLAMLTSMHALTLGKTLSPASRE -KLLGWMLANTTGDHCLRAGAP-GWKVADKTGSGP-GTRNDIGLLWAPGASPILVTSYLTE -SKAAPKARDAALASVAAEVVKLw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00455 TaxID=1703927 RepID=A0A1Q5N6F9_9ACTN -----VRELATLERDHSARLGVYARNTATGETV-LYRADELFPMCSLFKPLAVAAVLRDLD -RDGEVLARRIHYTEQDVVKHAPVTGRNLAAGMTIEQLCAATICQSDNAAGNLLLRELGGP -GAVTRLCRSLGDGVTRLDRWEPELNSAEPDRLTDTTSPRAIGRAYGRLALGDALSPRDRE -RLTGWLLANTTSTERFRKGLPADWTLADKTGGGQYGTNNDAGITWPPHRAPIVMAVLTTR -HQPDAAADNPLVAAAAALLA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bradyrhizobium sp. YR681 TaxID=1144344 RepID=J3I3P1_9BRAD -------ELETYERESGGRIGVYAENLATGAKI-AWRAEERFVMCSTFKASLAACVLARVD -RGEEQLSAMIPYSKADLLEYAPVARQNIPAGMSVAEMCKAIVELSDNTCANLLLARIGGP -PALTAFWRSLDDTISRLDHNEPELNRSPPGAPHDTTTPAAMAGNLKRLVTGEALSPASRA -QLTDWMVNCKTGANRLRAGLPAGWKIGDKTGNNGKDASGDIAVAWPKSDAPILIAAYTQG -GTPSTAQIEAVFAHIGRMVTE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C15FEE9 ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2Z3YEZ3_STEMA -----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRASIITSDNTAANLLFGVVGGP -PAVTAFLRTSGDAVSRSDRLEPELNSFAKGDPRDTTTPGAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces aureocirculatus TaxID=67275 RepID=UPI0004C9B5F2 -----ARAFKELEREFDARLGVYAVDTGTGREV-AYNDGRRFAYNSTFKALAAGAVLRENT ---PAGMDKVVKYSKEDLIANSPVTEKHVDTGMSLRALCDAAVRYSDNTAANLLFDELGGP -EGLDADLEKLGDHVTRVERVEPFLSRWVPGEKRDTSTPRALVKDLRAYVLGDVLDEPDRA -LLARWLKTNTTGDNVIRAGVPKTWVVGDKTGTGSYGARNDIAVVWRPDAAPLVVAVLSHR -ADKDATPDDRLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia thermophila TaxID=1848 RepID=UPI001161161B -------------ARRGVRLGVHAVATADGREL-AHRADERFAHCSIVKVLAAGAVLDRFP ---IEQLDRRLPVEAADLVAHSPSARAHVGTGMTLREAAEAALRYSDNTAGNLLLRAVGGP -EGITAFVRSLGDPVTRSDRWEPALNTAVPGDERDTSTPRALSADVRELVLGSRLDVAARE -LLRGWMLANTTGDARIRAGAPAGWRVADKTGTGGYGTAGDAAVLWPPQGAPIVLTVLTAG -DHPDAQPDEAVFAEVTRIVT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Lentibacillus salicampi TaxID=175306 RepID=A0A4Y9A931_9BACI ------EKFLQLENEFDAQLGVYAMDTGTSQTI-EYRPNERFAYSSTFKPLAASILLKQNN ---IEDLEKVVTYTNNDLVTYSPVTEKHVDTGLTLLEISEAAIRKSDNTAGNLLLEAIGGP -DKFEQALRDIGDDVTHPERYETELNEFTPGNNRDTSTPRAMATNLKKIALSDFLPDDKRE -LLIDWMTGNESGDPLIRAGAPEKWTVVDKSGAGTYGTRNDIAIVWPPKKEPIVIAIMSRH -DTEDAEYDDSLIAKAAEITLNAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CG 926 TaxID=1882405 RepID=UPI000D6B8504 --------LRALEREYGARLGVYALDTATGRTV-VHRADELFPMCSVFKTLAAAAVLRDLD -HDGAHLAKRIHYTPQDVTDGGSITEKNIANGLTVAELCSAAIAQSDNTAGNLLLRELDGP -TAITRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLTIGDALDSGDRE -RLNRWLLSNTTSGDRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPMVLAILSTM -PEATAPRDNTLIARTAKLLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. 1(2017) TaxID=1404888 RepID=UPI00140F0D39 -------ELAAYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEERLAAMISYGQADLLEYAPVAKQNLAAGMSVADMCKAIVELSDNTCANLLLARIGGP -AVLTAFWRSIGDTTSRLDHNEPELNRSPPGDSRDTTTPAAMAGNLRRLVLGEALSPASRA -RLTEWMVGCKTGANRLRGGLPANWKIGDKTGNNGKDASGDIAVAWPRADTPILIAAYTQG -GTPNPAQIEAAFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_058 TaxID=2175635 RepID=UPI000DAA1CBD ---ATARAFAALERQYDARLGIAAVDTGSGRTI-VHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADAGAEPSDALVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A2Z5JMP5_STRAR ----AVRKLRDLEREHAARLGVFGWNTVTGRSV-LHREEERFPMCSTFKTLAVGAVLRDLD -HDGTFLSEVIHYTKQDIKRGAPVTGENLAHGMTVEDLCGAAISYSDNTAANLLMERLCGP -TSVTRFCRSIGDSVTRLDRWEPELNSAEPGRVTDTTSPRAIGKTYAQLVLGGALEAGDRK -RLTGWLLANTTGGKRLRAGLHEDWSVGDKTGTGSYGTTNDVGIVWPPGQGPIVMAVLSTK -HDADSEADDPLIAHAAAILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium diazoefficiens TaxID=1355477 RepID=UPI000428C8CA -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGQEQLAAMIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNKSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWLVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GSPTAPQIEAVFARIGRMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Gracilibacillus saliphilus TaxID=543890 RepID=UPI0013D28312 -----DEEFAQLEDEFEAQLGVYAIDTGENQIV-EYNPDERFAYASTFKVLAAAILLKQNE ---IKDREKAVTYSKDDLVTYSPVTENHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -EEFQALLRDLGDDVTEPERYETELNEFMPGNKSDTSTPKVLATNLKKIALEDFLPNDKRE -LLIDWMKGNATGDTLIRAGLPEEWVVGDKSGAASYGTRNDIGIVWPPNREPIIIAVMSRH -NTKDAEYDDELVAKAARIIFD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1W6ALB5_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. J35 TaxID=935852 RepID=UPI00048CB86D ----TAADFAALEAASGGRLGVSLLDTATGQAR-GHRQDERFPMCSTFKALLSAAVLAGAD -RGQWSLDRRLPVGEGDLVPHSPVTRRHVGKDLTVRDLCRATMTTSDNAAANLLSGLIGGP -AALTAFLRAHGDAVTRNDRLEPVMNGFAPDDPRDTTSPGAMAASMARFAVGDVLAPASRQ -QLADWLIDNGTGDACLRAGLGPRWRVGDKTGSNGVDTRNDVAVLWPLDGRPWVLAAYLQG -ATVDSDARDAVLARAARLA---- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella pseudohinzii TaxID=1331258 RepID=A0A0M7G847_9BORD ---DAQRQLARLEAREGGRLGVSLLDVQSGYAI-AYRADERFALCSTFKLLAVGAVLTRVA -RGEDDLSRPMRLSAADIVTYSPVTQQRLNEGMTLGQLCEAALLWGDNTAANLLLSTIGGP -PGLTAYARALGDGVTRLDRLETALNEARPGDERDTTTPAAMLGNLRQLVLGDVLPAPERE -RLRDWLMQCRTGRERLRAGLPAAWALAHRSGAGGHGSCNDIGVAWPAPAAPVLISAYLTE -SPLDLPGRERVLAEAARILAH-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=A0A268S5Q3_BACCS ------AVFKALEEEYAARLGVFALDTGTGQTV-SYRADERFTYASAHKPLAVGVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFDEIGGP -EGFKEGLRAMGDTVTEPERIEPELNNVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAILSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q3WRE7_9BACT ---TVVAKLAKLEKSLDGRLGVYAFDTATGAQL-HYRADERFPVNSTFKALLGAAILDRSE -HEVGFLERRIRFSNSDLVTHSPVTGEHLADGLTVAQLCAATIQTSDNTAANLLMKILGGP -SGVTAYARSIGDHKFRLDRWETELNTAIPDDLRDTSTPKAMAQSLRRVTVGHALEAEQRQ -RLITWLRGSTTGAKRIRAGVPKNWIVGDKTGTGEYGTAHDIAVLWPPRRRPIV------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. A23 TaxID=2606593 RepID=UPI001278AF80 -------DFAPLEREFDARLGVYAVDTGSGREL-AHRADERFGYASTHKAFSSAAVLQRTS ---LDGLAKVLKYTRADLQPNSPVTEKHVATGISLRDAMDAALRYSDNTAANLLFGELGGP -QGLGAALRAIGDTTTHVDRTEPGLNDLAPGDLRDTSTPRAMATSLRVFTLGAALPPEKRA -VLTDMMRANTTGAAVIRAGTPAGWTVADKTGTGDYATRDDIAVVWPPGRAPIVLVVMSDK -KAKDATADDRLIAQAAKLVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 7 TaxID=1416805 RepID=UPI000B9EEC97 ---TVAETAARVEARLGGRVGVALQRLGEPAVA-LYRADERFPMASTFKALACGALLAKVD -AAEQSLDTVVLYGPETLVTYSPVTAQHVGKGMTLAQLCHATITLSDNTAGNLVLRRIGGP -AGLTAFLRSTGDEMSRLDRWEPELNEALPADPRDTTTPRAAAGTLGRLLFQGVLSPGSSH -QLEAWMIADQVADELIRASLPQGWGIGDKTGSGERGSRSIIAVIRPPHGKPWLASIYLTG -SSSRPQERNAAVAEIGRSMI--- ->[subseq from] Beta-lactamase n=1 Tax=Curvibacter sp. PD_MW3 TaxID=2027918 RepID=A0A2D0ICI7_9BURK ---EWTRALQELEARSGGRLGVAIRDTGRGAQL-LYRADELFPLCSTFKLLLAAYVLHRVE -QGAEGLERRVLYPASVLVAHSPRTAPHAEGGMTVAQLCDATLVISDNTAANLLLGRHGGP -QALTAWLRSLGDTQTRLDRYETELNSALPGDPRDTTTPQAMLATMDKLLLGSALGTASRA -QLLAWLRGNLTGDHALRAGFPNGWVVGDKTGSGDLGTRNDVGIAWPAEGAPLLVASYLTG -AQLTPAQRDGVHAEVARLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. UNCCL17 TaxID=1449051 RepID=UPI0009DE8C6B ---ATARAFVALERRYDARLGVVAVDTGSGRTI-AHRAGERFAFASTNKVFIAAAVLDASS ---DTDLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTHVDRVEPDLNEATPGDRRDTTTPERFAEDLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWQVADKTGTASYGVRNDIAIVTPPGQEPIVLVVMTSR -ADPGAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Ruegeria sp. Alg231-54 TaxID=1922221 RepID=UPI000D552973 ---PLTETVQSWERRLDARIGLLLYDPSNEWEV-SYRADELFPMSSTFKPLLCGAVLAEVD -AGTESLSDHVKYQTTDLVDYSPVTSKHVETGMTVGALCEATMTISDNAAANLLLRRLDGP -AGLTEFLRTNGDDITRLDRWETALNEATPGDPRDTTTPRAILATLDRLLFGRALSPASSA -QLRQWMIDDQVADGLIRAHVPDGWTIGDKTGAGGHGSRAIVAFLQTPEPRTYLAAIYLTE -SDAPFPERNAVLSDIGRAMI--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas arboricola TaxID=56448 RepID=UPI000E0ED1C3 ------------------------LDSATGKHF-GQREDERFPMCSTFKFVLAAAVLRRVD -EGKLTLAQRVKIRASDMLSHAPVTERHVGGSLSVAELCRATMIYSDNPAANLLFPLVGDP -QGLTAFLRGIGDTQTRSDRHEPEMNRFAQDDPRDTTTPAAMALTLRTLLLGDALQPASRK -QLSDWMIDNRTGDTCLRAGLPRSWKIGDKTGSNGTDTRNDIAILWPPKGAPLLLTTYLNG -ASVDSDARDAALKAVAQAVASH- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0009F3D982 ------AGFERLERAFGARLGVYAVDTATGREV-AYRADERFAYASTHKVFTAGGVLQRTP ---VAELDRTVTYSRQDVVANSPITEKHVGTGMPLRAVMDATLRYSDNTGGNLLFRELGGP -AGLTAVLRGIGDTTTHVDRIETELNDTAPGDIRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDIMRGNTTGDANIRAGVP-GWAVADKTGTASYGTRNDIAVVWPPNRAPIVLSVLTDR -STKDAQIDNALLAQATVATV--- ->[subseq from] Beta-lactamase n=1 Tax=Delftia sp. (strain Cs1-4) TaxID=742013 RepID=F6AWV3_DELSC --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQCDAALAAAGKAAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=A0A4Q0RRI9_9BRAD -------ELESYERESGGKIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDKLAAMIPYGKADLLDYAPVAKQNLSAGMSVADICKAAVELSDNTCANLLLARIGGP -AALTTFWRSIGDTMSRLDHIEPELNRSPPGDVRDTTTPAAMAGNLKRLVAGEALSPASRA -QLTEWMVGCKTGANRLRGGLPKAWKIGDKTGNNGKDASGDIAVAWPKLDAPILIAAYTQG -GTPNPTQFEAVFASIGRRVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. CC120222-04 TaxID=1378088 RepID=A0A239Q4H2_9GAMM -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDTLSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAIGYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus soli TaxID=480284 RepID=A0A0Q9XY39_9BACI -----DADFAKLEEEFDARLGVFALDTGTGETI-SYRADERFAYASTHKALAVGALLQQIS ---IEDLNQKVIFAEGDLVNYSPITEKYVDKGMTLSELSEASLRYSDNTAGNLILKELGGP -DEFKKALKKIGDDITKSERFEPSLNEVKPGETHDTSTPKALATSLKAFTLEDELQKEKRL -MLVDWMKRSTTGDTLIRAGVPKDWEVADKSGAALYGTRNDIAIIWPPNENPIILAILSDR -ATEDADYDDKLIEQAAETVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-31 TaxID=1463898 RepID=UPI0004C71D4A -----QAELAELERRYGARLGVYALNARTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDQG --GRAPMDRVLHYPPHDSMANSPETDKHQATGMTVADVCAAAIQYSDNAAGNLLLREIDGP -AGLTRFFRSLGDEVSRLDRWEPELNAAVPGELLDTTTPQAIASVLERLALGGALAGADRE -RFVGWLKGNTTSGRRFRAGLPREWVVADKTGTGSYATANDVGVAWTTRQTPVVLAVLSSK -TMPDAPVDEALIADAASIVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. ozaenae TaxID=574 RepID=A0A378B1E3_KLEPO ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVAPAWP-------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas TaxID=40323 RepID=A0A2G7S026_9GAMM -----ATDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWILTAYLQA -GAISFEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_031 TaxID=2175653 RepID=UPI000DA80355 ---ATRRAFDGLEGAHDARLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAS ---PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDDTAANLLVARVGGP -SVVQQWLRGIGDQVTQVVRIEPDLNEATPGDDRDTTTPAQFAADLRTVLLGDALQPDDRE -LLVDTMAGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR -STADAEPDDALVAAATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5770 TaxID=2690308 RepID=UPI00136EC469 ----HRREFRALESAFDARLGVYAIDTGTGREI-AYRDRERFPYASTFKALAAGAVLRE-- -EGLGGMERVVRYTKEELVEPSPVTEKHVGTGMTLDALADAAVRYSDNTAGNLLFEELGGP -KGLQAVLRSLGDGVTRMDRIEPELGDWKPGEVRDTSSPRALAGDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SGREAEPDNRLIARAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00099857E5 -hpDVTARLNALEAQHGARVGVFAHNLGTRQTI-RHRADERFPVCSLFKTLAAAAVLRDLD -RSGEVLSKRVHYTADDLVDGSAETEKHLTEGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAITRFARSVGDRATRLDRWETELNSAEPWRITDTTTPYAIGRTYARLVLDDVLNRPDRE -LLTHWLLTNTTSDNRFRLTLPPTWTIADKTGAGSYGTNNNVGIAWTQKGTPVVLAVQTTK -PAQDAAPDNPLVAETARLL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. yr375 TaxID=1761906 RepID=A0A1H9LF45_9ACTN -------RFGDLEREHSARLGIFAHDTGSGRTL-AYRADERFPLCSVFKALAVSAVLRDLD -QAGEYLAERIHYTKDYVTAYAPITDEHVAGGMTVEELCAAALSHSDNGAANLLMRELGGP -AAVTRFARSLGDATTRLDRWEPELNSAEPWRTTDLTSPRAIGRTFARLVLGRALPPADRT -RLTGWMIANTTNTERFRAGLPADWVLADKTGGGQYGVANDVGIVWPPGRAPLVLAVLSTK -HASEGPSDNPLVARAAELVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum B str. Osaka05 TaxID=1407017 RepID=A0A0S6U3G4_CLOBO ---QYNSAFSQLESDYDVKLGIYAFDTEMNKEV-AYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKKVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP -SGFKSALNQLGDNVTQPARIEPELNEAMPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKKAKYDDKLIAQVSKIVFDSf ->[subseq from] IMI-1 n=6 Tax=Enterobacter cloacae complex TaxID=354276 RepID=Q46991_ENTCL ------DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIAID-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0M1EST1_STEMA ------ADFAALEKASGGRLGVAVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDMNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces prunicolor TaxID=67348 RepID=UPI000375D818 -------GLRALEEQHTARVGVFAHHLGTKKTV-VHRADELFPMCSVFKTLAAAAVLRDLD -RHGEVLYKVVHYTEADLVDGSDQTRAHLAEGMTVEQLADVAVRFSDNGAGNLILRELGGP -TAVTRFARSLGDRVTRLDRWETELNSAEPDRITDTTSPRAIAGLYRKLVLGDALRRPDRD -RLTAWLLNNTTSAARFRAGLPASWTIADKTGSGDYGTANDVGIAWTEAGDPVVLAVLTTK -PTPDAPYDNQLVADTAKLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. HMWF023 TaxID=2056859 RepID=A0A2R7IJF2_9GAMM -----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLVATVLKQAE -RDPALLDRRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFALDDPRDTTTPAAIAATLRRLVLGDALKPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWIVTAYLQA -GAISFEQRAAVLAQVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobiales bacterium Sp-1 TaxID=2608987 RepID=A0A6A7Y346_9RHIZ -----VAKFTAIEQAHGGRLGVVAVEAGTGRRI-AYRGDERFPLCNTFEILAAGAVLARVD -AGEEHLERRVIFHEDDVVEGSPATQGHVRPPLTLAEICAAATEYSDNTAANLMLRSLGGP -EGLTAFLRSLGDTESRVDRYEPELNDVKPGDPRDTTTPAAMAADLEKLLLGPVLSPTSRA -QLAAWMIACKTGLERLRAGLPADWKAGDRTGADGLLVTDDVAILWPPERPPILVAAYYAG -GAGAPRQQDAVLAEVGRIVAAAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. DK17 TaxID=186196 RepID=UPI000309B7D1 ---SLDATIDALEAQYSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIESGDLVENSPVTAAAVGAPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAITALARDVGDGGTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPLVLAILTDS -LTQDAQGNNQAIADTTAAVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus galactosidilyticus TaxID=217031 RepID=A0A177ZRZ0_9BACI -----DADFAKLEEEFDARLGVFALDTGTGETI-SYRADERFAYASTHKALAVGALLQQIS ---IEDLNQKVIFAEGDLVNYSPITEKYVDKGMTLSELSEASLRYSDNTAGNLILKELGGP -DEFKKALKKIGDDITKPERFEPSLNEVKPGETHDTSTPKALATSLKAFTLEDELQKEKRL -MLVDWMKRSTTGDTLIRAGVPKDWEVADKSGAALYGTRNDIAIIWPPNEDPIILAILSDR -ATEDADYDDKLIEQAAETVI--- ->[subseq from] Beta-lactamase L2 n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=BLA2_STEMA -----ATDFAALEKAVRGRFGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RQPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRSIGDAVSRTDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQLASRQ -QLADWLIDNETGDACLRAGLGKLWRVRDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A1D8IH59_9BURK ---TFQQSLAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQGYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Variovorax sp. BT01 TaxID=2135732 RepID=A0A4R1VPU2_9BURK --kEAAAQLADIERRSGGRMGLYAIDTASGRTL-AHRGAERFAMASTFKLLLASAVLHLED -RQPGSLDQRLPVRQADLIAHSPITSKHLEDGITARQACEATVTVSDNGAANLLFPMIGGP -QGLTRFLRECSDSVTRMDRTEPTLNTNLPNDLRDTTTPQAMAQTMRRLLVGNVLTPTSRD -QMNAWLQGATTGFARLRAGLPKDWRTGDKTGTGENGAANDVAITWPTGRAPILMAVYLSG -STQPGAVLDATHAQAAAVVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomycetaceae bacterium MP113-05 TaxID=1380770 RepID=V6L4G2_9ACTN ---DIAGRLRELEQRHSARLGVFAHDTATGRDV-RYRAHERFPMTSTFKTLAAAAVLRDLD -RDGEFLARRVHYTERAVEKYAPVTGENLARGMTVEELCDAAIRFSDNAAANLLLRELGGP -RAVTRFCRSIGDRITRLDRWEPELNSAEPWRRTDTTTPRAVAGTYARLTLGDALDRGDRR -RLTRWLLGNTTSDAKFRTGLPGDWTVADKTGGGEYGTNNDVGLTWPPGRPPIILAVLTTR -FAPDAERSDPLVAETAALLA--- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase IMI-19 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI0010C2FDF8 -------DIKNLETDFNGRIGVYALDTGSGKSF-TYKANERFPLCSSFKGFLAAAVLKRSQ -DNQLSLNQIVNYNTRTLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDEDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTIALGNILSEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -YEKEAKHEDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. XY66 TaxID=1415563 RepID=UPI0006AEB0AE -----VRRLRALEREYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDDRFRAGLPRNWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. (strain R39) TaxID=72570 RepID=Q60225_ACTSP --eDLSGEFERLESEFDARLGVYAVDTGTGEEV-FHRADERFGYASTHKAFTAALVLGQNT ---PEELEEVVTYTEEDLVDYSPITEQHVDTGMTLLEVADAAVRHSDNTAANLLFEELGGP -EGFEEDMRELGDDVISADRIETELNEVPPGETRDTSTPRAMAGSLEAFVLGDVLEEGPRD -VLTEMLLNNTTGDELIRAGVPEDWRVGDKTGGGSHGSRNDIAVVWPPEDDPIVIAVMSTR -EQEDAEFDNALVSGATEVVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces alboflavus TaxID=67267 RepID=A0A1Z1WJM7_9ACTN ----HRRRFADLEREFDARLGVYALDTATGATL-AHRADERFAFCSAFKALAAAAVLDGNP ---LSHLDKRVTYSRADLMKHAPVTARHVDTGMTIRQLCDAAIRHSDGTAGNLLLRDLGGP -DRLTAYARGLGDKVTRMDRVEPAITQATPGDPRDTSSPRAFGGTYQKIVIGDALPGRKRA -FLLDLLQRNVTGAERIKAGLPRGWTIADKTGTGDHGTLNDIAVLWPPRSPPVLLAIMTSK -AAKDAPYDQALLAEAAEYVT--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0A0NJS0_STRRN -------RMRELEREYGARLGVFALDTGTGRAV-THRADERFPICSVSKTLAVGAVLRDLD -RDGEYLARRIRYTEDDVKTHIPITGTNIANGLTVEELCAAAISYSDNGAMNLLLRQLGGP -TAVTRFCRSLGDGITRLDRWEPDLNSAEPGRVTDTTTPRAIGRTYAGLAVGRALDTGDRE -RAAGWLVANTTGDARIRAGVPGGWTVGDKTGTGRYGTTNDVGIAWPTDRAPIALAVLSTR -PEQDAEAVDPLIAKATALAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=UPI0002A22007 ----LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPSDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVIK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. NWU339 TaxID=2185284 RepID=A0A2U2ZDK6_9ACTN ---EIMRRLRDLERRHSARLGVYARDAATGRTV-RYRAHERFPVCSLFKTLAVAAVLRDLD -RDGEFLARRIRYTGKDVTDYAPITGKNLADGMTVAELCAATICHSDNAAGNLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPWRTTDTTSPSAVGRTYARLVLGTALAVGDRE -RLTDWLLANTTGGAKLRAGLPSDWTVADKTGGGMYGTNHDVGIAWPPGRSPLVMAVLTTK -HEPDASPDNPLIAETATLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. GW2 TaxID=1211114 RepID=UPI0002EFFDD1 ------PDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD -RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGA -AALTAVLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLGRCVAGVVLAPASRL -QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLGGSPWVVAAYLEG -SRVDSAARDAVLARAGQLAV--- ->[subseq from] Beta-lactamase n=2 Tax=Nocardia nova TaxID=37330 RepID=W5T6V8_9NOCA --nSAQDRLRGLEAGLGGRIGVYAVDTGTGRIR-AYRADERFPFASTYKALAAGAVLERNK ---PEALDSRIHYSRDDLVAHSPITGQHVDDGMTLREILDAAVRYSDNTAGNLLFRAVGGP -KPLQQQLHEIGDDATSMDRTETDLNQTAPGDIRDTSTPRALGADLRYFALDAAVSQENRR -ILGGLLRANTTGDTLIRSIAPAGWDVGDKSGSGTYGTRNDIAVLWPPGRAPIVLAVLTTR -DRPDAEYDDTVVARAAAIAVT-- ->[subseq from] Exo family class A beta-lactamase n=1 Tax=Streptomyces sp. CNQ431 TaxID=1571532 RepID=UPI00053D09A5 ---DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TGEDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PVA 94-07 TaxID=1223307 RepID=V4IXJ6_9ACTN ---DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TGEDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A3S4A0P0_9ACTN ---DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TGEDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A068F868_ECOLX ----VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD -KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP -EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNGSVLTEKSRK -KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN -THSSMNELNEHIAGIGDSVIKNw ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus gahaiensis TaxID=1706839 RepID=A0A4U0R337_9RHOB ---TITEAARAIETDLGGRVGVSLRQPGGAGAT-GYREDERFPLSSTFKAPLCGAILTLVD -AGEDQLDRVIGYSPGDLVTYSPVTETR--DAMTVAELCEATITLSDNTAANLLLDRLGGP -EDFTEYLRAIGDDTTRLDRWETDLNEAAPGDPRDTSTPAAMTATLETLLFGPVLSDAAQR -QLEAWMQADQVADDLIRASLPEGWEIGDKTGAGGYGSRSIIAVIRTPQGDPWLASVYLTG -NEADMPTRNRAIARIGAAIVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=UPI001414EBA0 -----QPDFAPLERDFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSTAAVLQRTS ---MAGLAKVLPYTSADVQPNSPVGEKHAGTGLSLRDAIDAALRYSDNTAANLLFRELGGP -AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAADLRAFALGTALPAEQRT -FYTDTMRANRTGDALIRAGTPAGWTVADKTGTGAYATRNDIAVVWPPGRAPIVLVVLSDR -KTADADHDDRLIAQAAKLTLDTy ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. M39 TaxID=1825094 RepID=A0A178XH41_9PSEU -----QPDFAALEKAFDARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRAWSKDLRAVALDSGLPADKRA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYATRNDIAVLWPPHRAPIVLAVLSDR -RQKDAKTDDKLIARAAAAVVK-- ->[subseq from] Beta-lactamase AXC-2 n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A346DAP7_9BURK ---TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=UPI000A32897F ---ALDQALADLEKQSRGRLGVALTDTATGQVA-SYRGDERFLMLSSFKTLAAAYVLARAD -RGEDQLTRRMPIAESDLVEYAPVTKQHVGPRMTLAELCHATVTTSDNTAVNLMHRSYGGP -QALTRFIRSLGDTVTRHDRYEPELNVPHPTEPMDTTSPHAMNRTLGALLFGKALKPESRE -LLQSWLLANTTGGKRLRAGLPADWKVGEKTGTYSRVGSNDAGFARAPGGSPIIVSVYLET -TAIPMPERDRIIADVGRQVA--- ->[subseq from] Beta-lactamase n=2 Tax=Roseovarius mucosus TaxID=215743 RepID=A0A1V0RSP0_9RHOB ---HLAATIDRIEQELDARVGVVIRDSGSDWTV-SHRAEERFLMASTFKTMLCGAVLHRVD -EGDLDLEERIAIEAAEVLEYAPVTEKMVGETMSVGELCHAALDMSDNTATNLLIDRIEGP -QSVTAFLREIGDPVSRLDRREPDVNTFAPDDPRDTTTPEAMVSTMETLLTGGALSPQSRA -LLVDWMSDGGVTGALIRASTPAGWHVADRSGSGNF-NRNIVAMVTPPDREPYFIAIFLSD -ADADFNTRNGAMIELSKAVMQ-- ->[subseq from] Uncharacterized protein n=2 Tax=Xenorhabdus hominickii TaxID=351679 RepID=A0A2G0Q4X7_9GAMM ---QIIDQLAILEKNANGHLGAVLIDTADHSVI-SYRADQRFPLCSTSKFMAVSAILKKSE -TDNHLLNQRIHYQQSDLVEYSPITEKHLKNGMTLGELSAATLQYSDNSAMNLLLDQLGGP -NEVTKFARTIGDNHFRLDRKEPELNIVEPGDERDTSTPQAMADSLYNLTLGNALAAEQQE -LLANWLKGNTTGGTSIRAGVPEDWLVGDKTGRCDYGSTNDIAVIWPTNKAPLILVTYFTQ -PNKKAIARPDVLATAARIMTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A1K1ZFM6_STRAR ------GQLAALERKFEARLGVYALATGTGATI-THRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVIRYTEGDLMKSSAITRQHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -ARFTAYVRSLGDTVTRMDRIEPTIAQATPGDPRDTTSPRAFGTNYRKILLGDALPTDKRT -FLRHLLERNGTGAQRIRAGVPRGWNVADKTGTGDYGTLNDIAVVWPPNAAPLVIAIMSSK -ATKDAKYDQALLAEAAAYVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048E2A73 -----DREFRRLEQRFDARLGIYAIDTGTGRTV-RYQADERFAYASTYKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPVTEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDEVTDAARYETALNEATPSDRRDTSTARALTEDLRQYAVDDALEPADRD -ILNAWLRGNTTGGALIRAGVPDGWVVGDKTGAAGYGTRNGIAVIWPPDRAPIVLAVLSSR -DERGASYDDALIAQATEVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TP-A0875 TaxID=552354 RepID=UPI000A43160D ------ARLRELEERYAARLGVYAHDTATGRTV-RYRADERFPLCSVFKTLAVAAVLRDLD -RDGEFLGRNIRYTERDVTEHAPVTGEHLAAGMTVGALCSAAIRHSDNAAANLLLAELGGP -SAVTRFCRSIGDGTTRLDRREPELNSAEPWRTTDTTSPEAVGRSYARLLLGTALGRGDRA -LLTGWLLANTTGDEKLRAGLPADWAVAEKTGSGGYGTGHDVGVAWPPGRAPLVLAVLTSG -TEPDAVADSALIAGTATLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02009 TaxID=1703938 RepID=A0A1Q5J6T2_9ACTN ---DLLARLRELEERHSARLGVFAHDVRSGRSV-AYRADEHFPMCSVFKTFAVAAVLRDLD -RDGSFLARRIRYTAADVERWSPKTEENLAHGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFARSIGDRTTRLDRWEPELNSAEPWRRTDTTTPRAAGRSYGRLLLGDALPVEDRE -RLTAWMLGNTTSGERFRKGLPADWILADKTGGGRYGGNNDAGVTWPPDGGPIVLTVLTTR -FVEDAAPVDPLVADAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI0013DF92C0 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSHGIIAALGPDGKPSRI------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseorubiginosus TaxID=67304 RepID=UPI000F4BBD6E ---DVSTRLRALEQRYDARLGVFAHRPTTGRSV-RFRADERFPMCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVQGSDQTAAHLAEGMTIAELAEVAITHSDNTAGNLLLRELGGP -TAITRFARSLGDGVSRLDRWEPELNTAEPWRLTDTTSPYAIGRTYGRLVLGDALNRRDRD -LLTHWLLSNTTSVDRFHAGLPKTWRIADKTGSGSYGTANDVGVVWTGKGDPLVLSVLSTM -PEPDAVRDDALVADAAAVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus obscurus TaxID=1861 RepID=A0A1I5H311_9ACTN ----VSGEFATLEERFDARLGVFAVDTGSGATI-EHRADERFAYASTIKALAAGALLAQTS ---PADLARAVPIAAADLAPYSPVTETRVGGSMTLAELCDAAVRFSDNSALNLLLRELGGP -AGLDAALERVGDTVTEVVRDEPGLNSAVPGDPRDTTTPRALAGSLRAYALD-AAAPEDRE -QLVDWLRRNTTGDALIRAGVPDDWDVGDKTGTGAYGTRNDVAVVIPPGRSPIVLAVMSSR -DEPDAEHDDALIAETTRVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter subterrani TaxID=1658765 RepID=UPI0009E60D7F --kDISNQLRQLESQYGGRLGVALMNCSTGAVA-SHRGDERFLFNSTGKLFIAAAVLAQVD -RGDAALDLRLVVSESDLGGWTPITEKHLGEPMTVAELCQAVVAWSDNAAANVLVRFVGGP -EAVTAFLRSIGDDVTRLDRYEPELNEDHEGDKRDTTTPLAMMKTLQRLLLGEALSPSSRH -QLAAWMIEGKTGDARLRAGMPSSWLIGEKTGTNGVGNANDIGIAWPADRGAVVAVAYTFG -PKASKEQRDDVIAMIGAMA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces luteocolor TaxID=285500 RepID=UPI000852A75C ---RLKGRFEALEREHGGRLGVFALATGTGATL-AHRADERFAFCSTFKTLAAAAVLHHNP ---LGHLDKRVTYTAADVDSISPITEKHIATGMTVRELCDAAVRHSDGTAGNLLMRDIGGP -RRLTAYLRGLGDTVSRMDDYEPELNDVPPKDPRDTTTPRAVAAVYRALVLGDALSAAKRA -LLKDWLLRNAVGATRIRAGLPKGWTVADKTGTGNWGRANDIAVIWPSGRDPLVLAVMTDR -PGRDARTKDALLAGAAKAAAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Hydrogenophaga sp. IBVHS1 TaxID=1985169 RepID=A0A1Y2QT27_9BURK ---NLRDSLREIEATARGRLGVHIIDTATGREH-GWRSDERFLMLSSFKLLASALVLDRVD -RGVEKLERRIRYRKQDLVSWSPVTERHVGGALSLAQLCEATITTSDNTAANLILASYGGP -AALTTYVRGLGDTVTRHDRIEPMLNNAASGEPLDTTSPRAMAHTVRALLLGDALKPSSRE -QLMNWLLANTTGGKRLRAGLPAGWRIGEKTGTAND-DANDIGMAMPPQRAPIIVTAYLAE -SRTDAATREAALASVGRLLAQ-- ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. SID10815 TaxID=2706027 RepID=A0A6B2V431_9ACTN ---RAETELTELERRFGGRLGVYAMDTGTGEEV-RHRADERFLMCSTHKALTVAAVLRAHQ -DRPALLKQVIHYRRSDLLDYAPVTSRHVGEGMTVAALCRAAVTRSDNAAANLLLRTVGGP -AAVTRFVRTLGDPVTRLDRDEPHVNEA--DGVLDTTTPAHFGASVRALTLGDALEPRGRG -QLLAWLDANTTGDRAIRAGCPKGWRIGDKTGSGDHAESNDIAVIRPPRHAPLVLAVFTAP -DDPKSTTGQHTIAEAARIVT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_047 TaxID=2175654 RepID=A0A2W1ZPV6_9MICO ---ATRRAFDGLEGAHDARLGVVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLEDAS ---PADLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLHAMLRSSDNAAANLLVARVGGP -SVVQQWLRGIGDQVTQVVRIEPELNEATPGDDRDTTTPAQFAADLRTVLLRDALQPDDRE -LLVDTMVGTTTGDATIRAGVPTGWTVADKTGTGSHGVRNDVGIVTPPGGAPIVLVVMTSR -STADAEPDDALVAAATRTAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Kurthia sp. Dielmo TaxID=1033738 RepID=UPI00112298E5 ----PQQDFKELEKKYDARLGIYVIDTATNKKI-AYHANERFAFTSTYKALAAGVLLQNAS ---LEQLETVILYTKDDLVAYSPVTELYTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP -KGFEQSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAIDLKKYTIDSTLSIEKRQ -LLLDWMTDNKTGDALIRAGVPTDWKVVDKSGAGSYGTRNDIAVVFPPNRAPIVLAILSSR -SEQNATYDNQLIEEATRVIIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=UPI000BE28CDD -------RFGELERRFKARLGVYAVDTGNGRTL-AHRADERFAHASTFKALLAAVLLRDLT ---DADLGRVVTYTQANLLEWAPVTSRHVATGMTVEALIDAAVRHSDNTAANLLLREVGGP -AGLQRELRKINDRVTYVSRTEPSLNEATPGDQRDTSTPRALGTDLRRLVLGDDLPPPRRQ -KLAALLRGNTTGGPYIRAGVPAGWTVGDKTGGGGYGTRNDIAVVWPPTGSPLVIAVQSDR -GVRDAASDDALIAEAAKAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3B0ACY9_9ACTN -----HRRLAELERRFDARLGVYGLATGTGDTV-AHRPDERFAFCSTFKGLAAAAVLDRRP ---LARLDTTVRYTEADLMASSAITRRHVRTGMTLRALCDAAVRYSDGTAGNLLLRDLGGP -AALTTYLRRLGDTVTRMDRIEPHIVEATPGDPRDTTSPRAIGTDYQRLLLGDALPDDKRA -FLRDLMERNATGARRIRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPASPPLVIAIMSSK -AGRDAEYDQALVAEAAAYVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 57 TaxID=2035243 RepID=UPI000EAB5F25 ----PQARLRELEKRHGARVGAFAHNLATGTTA-RHRAGERFPMCSVFKTLAVAAVLRDLD -RDGGTLARRLHYTAADVVAGGSITVKNVAAGMTIAELCDAAIRYSDNLAANLLLRELGGP -TAVTRFCRSVGDPKTRLDRSEPDLNTAEPWRRQDTTTPAAIARTYARLTLGDALDDDDRT -RLTAWLLGNTTSAKRFHEGLPDDWSIADKTGTGSYGTANDVGISWTPEGVPVVLAVLTTK -PAQDATPDDALVAATAKVLAD-- ->[subseq from] Uncharacterized protein n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=A0A1W6Z973_9BORD ---ALDQALADLEKQSRGRLGVALTDTATGQVA-SYRGDERFLMLSSFKTLAAAYVLARAD -RGEDQLTRRMPIAESDLVEYAPVTKQHVGPRMTLAELCHATVTTSDNTAVNLMHRSYGGP -QALTRFIRSLGDTVTRHDRYEPELNVPHPTEPMDTTSPHAMNRTLGALLFGKALKPESRE -LLQSWLLANTTGGKRLRAGLPADWKVGEKTGTYSRVGSNDAGFARAPGGSPIIVSVYLET -TAIPMPERDRIIADVGRQVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia anaemiae TaxID=263910 RepID=UPI0007A3C103 -------HLTELEQKFAARLGVYALATGTGTTI-AYRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDVTVTYTEADLLRNAAITPQHVASGMTIRELCDAAVRYSDGTAGNLLLRDIGGP -GELTAYARSLGDTITRMDRIEPAITEATPGDPRDTTSPRAIGTDYQKIVLGDALPEEKRA -FLRGLLERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPPNAAPLVIAIMSSK -FTRDAEYNQALIAEAAAYVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus albus TaxID=105425 RepID=UPI0005AA3BF8 ----ITARLRALERAHSARLGVFAADTVTGRTV-GYRADELFAMCSTSKTVTVAAILRDLD -RDGRFLAERVRYTEQDVTGYAPITGLNLAHGMTVADLCAAAIEYSDNTAANLLLREIGGP -PAFTRFCRSIGDGVTRLDRWEPALNSAEPGRVTDTTSPRAIGRTYARLVLGDVLGARHRE -RLTGWLLADTTSGNRFRAGLPKDWTLADKTGTGGYGTANDVGIAWPPGRGPVVLSVLTTK -HVSTAPADEPLVAEAAALLA--- ->[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=1 Tax=Hydrogenophaga sp. RAC07 TaxID=1842537 RepID=A0A1B3M2Q7_9BURK ----WQARLQQLEATAQGRLGVAILDTATGQVH-GHRADERFMMLSSFKLLASALVLARVD -RGQESLDRRITFAKTDLVTYSPVTERFAGTTMSLAGLCEATLTTSDNSAANFILDSFGGP -AALTRFARALGDDTTRLDRRETELNTGTAAALLDTTTPRAMALTMQKLLLGNALSPASRQ -LLQQWLVGNTTGDKRLRAGLPSGWRVGDKTGTNRT-DANDIGIAWPANGPPLIITSYLAE -STASSAVKEATLAGVARLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Compostimonas suwonensis TaxID=1048394 RepID=UPI000C23C065 -----PTAFAQLEDEYDVRLGVSGIDIGTGAIV-SYRADERFAYASTSKALLAGAILSEAS ---EPELDEVIRYTDDELVGHSPVTEEHIDTGMPLRDVLAAALQYSDNTAANLMFGRLGGP -GGLGDRLRAIGDSTTHVDRVEPELNEAVPGDIRDTSTPAALAADLRELAFGSALAPERRG -LLTDWLRGSTTGADLIRAGVPDDWAVGDKSGAGGYGTRNDIAILWPPTGSPIVLAVMSTT -TTEDAEYDDALIAAAARVAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000767DD11 ------ARMRELEREYDARLGVFALDTGTGRTV-AHRADELFPVCSVSKTLAVGAVLRDLD -RDGEYLARRVRYTEDDVKTHIPVTGANIANGLTVEELCAAAVSCSDNGAMNLLMRGLGGP -AAVTRFCRSLGDPTTRLDRWEPDLNSAEPGRVTDTTSPRAIGQTYARLAVGRALDAGDRK -RLAGWLVANTTGDARIRAGVPAGWTVGDKTGTGRYGTTNDVGIAWPQDRAPIALAFLSTR -QEQDAKAVDGLIAEATALAV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=A0A5E8P5L5_9MYCO ----LDDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAAGYRQVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDADNLRPLIGELTAAV---- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas TaxID=40323 RepID=A0A2J0SIN1_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLGTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -SAISYEQQAVVLAQVGRIA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=A0A285KBH1_9ACTN -------RFGELERRFKARLGVYAVDTGNGRTL-AHRADERFAHASTFKALLAAVLLRDLT ---DADLGRVVTYTQANLLEWAPVTSRHVATGMTVEALIDAAVRHSDNTAANLLLREVGGP -AGLQRELRKINDRVTYVSRTEPSLNEATPGDQRDTSTPRALGTDLRRLVLGDDLPPPRRQ -KLAALLRGNTTGGPYIRAGVPAGWTVGDKTGGGGYGTRNDIAVVWPPTGSPLVIAVQSDR -GVRDAASDDALIAEAAKAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0U028_STEMA ------ADFPALEKASGGRLGVTVLDTGSGRRIgGHRQTERFPMCSTFKSMLVAHVLSLAD -AGRLSLDTRVPVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP -AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLARFAVGDGLSAASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Hypericibacter terrae TaxID=2602015 RepID=A0A5J6MDI9_9PROT ----AEPDFKAIRARIGGSLGVHALDTQTGRRI-GYDDSSLFAMASTFKLPLAAAVLLQVD -RGQLDLDQAIPIHASDLVNYAPVTSTHLAQGITVRELLAAIIEVSDNTAANLLLDLIGGP -QGFTQFVRDLGDRVTRLDRFEPELNTNLSADLRDTTTARAMVDDMAGFLTGPVLSDASRT -LLIGWLVSSRTGLARIRAGLPSDWKAGDKSGSGANGAINDVAIAWPPGRKPILIAIYLSG -SSHTPDSLSAAHAEIATAIAREf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI96-15 TaxID=1522761 RepID=A0A3N6E8A1_9ACTN ---DAERRLARLERASGARLGVYAYDTGSGRAV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRIFYTQDDVDRGAPETGKNLANGMTVEELCEVSITASDNCAANLMLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLALGDALNPRHRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLTAK -TGEDAVRDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea septica TaxID=472695 RepID=UPI000BB5441A ------AVAQQEEQALKARIGIAVIDTGAESVA-SYRGNERFPLNSTHKALLCGALLSAQD -QGKLRLTERTQFDRAALVTYSPVTEKFVAPAMSWGQLCEAAIGYSDNTAANLLAKKLGGP -EAVTRFFADLGDKATRLDRFEPELNSAVPGDMRDTTTPLAVSETLQKLTLGTALTPASRA -QLLQWMRDDKVANALLRSVLPAGWSIADKTGAGEYGSRSIISVVSPENGKPLIIAIYITQ -TEATLAQSNAAIARIGKTIF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=A0A6B2DVD3_9PSEU -----QPDFAPLERDFDARLGVYAIDTGSGREI-AHRADERFGYASTHKAFSTAAVLQRTS ---MAGLAKVLPYTSADVQPNSPVGEKHAGTGLSLRDAIDAALRYSDNTAANLLFRELGGP -AGLAAALRGIGDTTTHVDRIEPGLNDLAPGDVRDTSTPRAMAADLRAFALGTALPAEQRT -FYTDTMRANRTGDALIRAGTPAGWTVADKTGTGAYATRNDIAVVWPPGRAPIVLVVLSDR -KTADADHDDRLIAQAAKLTLDTy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI0014289DD0 ---DVTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEDDLVMGSDQTKAHLAEGMTIAGLAEVAITHSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRLTDTTSPYAVGRTYGRLVLGDALNRRDRE -LLTHWLLSNTTSVNRFHAGLPKTWAIADKTGSGSYGTANDVGVTWTDNGDPIVLSVLSTM -PAPDAVRDDALVADAAAVIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. S69 TaxID=1641856 RepID=UPI00131C93A9 -------ALTAYERETGGRIGVYAENLVTGARI-AWRAEERFVMCSSFKASLAAFVLARVD -RGEDHLEQMVAYGPQDLLEYAPAAKQNLAKGMSVAEMCQAAVELSDNTCANLLLARVGGP -SALTAFWRSTGDSVTRLDHNEPELNRSPPGDPNDTTTPTAMVGNLRLFLLGEVLSQPSRE -RLTDWMLNCKTGNNRLRAGLPKDWRIGDKTGNNGKDASGDIAVVWPRPDRPVLIAAYTQG -GSPSAAQLEAVFSEIGRTV---- ->[subseq from] Beta-lactamase n=1 Tax=Niveispirillum lacus TaxID=1981099 RepID=A0A255Z271_9PROT ---DISSAIGKLERVRGGRLGVAMLDMQTGAAA-QWRGNERFALCSTFKFLLAAFILSRVD -AGVEQLDRKVLFDKHELVSWSPLTEPHVGQGLRIDALCEAIMIQSDNTGANVLMRESGGP -AALTAFLRQIGDRVTRIDRIEPDMNLVPTGEERDTTTPLSMLSLLRTLLMGSVLNPDSRQ -RLTDWMIDNRTGDTRLRAGLPRGWRIGDKTGSYG-AMNNDIAILWPPAGGPLLLTSYYQN -DTANAQERSAAHADLAALVARRy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT372 TaxID=1169154 RepID=UPI0003A46166 --kTTERRFRALEKEFDARLGVHAVDTGTGREV-AHGADRRFAYASTFKALLAGAVLRAYG ---MDGIDKVVTYTEADIVEYSPVTEDFTDTGMSLRELCAATLWYSDNTAANVLLRELGGP -DALEKVLEELGDDVTEMDRIEPDLSEGKPGDVRDTSTPRALTAGLRAFLLGDALERRERE -LLRTWMATNTTGETLIAAGLPRDWTVADKSGTAGYGGRNDIAVVWPDDGNPILFTVLSSR -DEKDAERRDALIARAATVALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. G22 TaxID=1839752 RepID=A0A160ULU4_9BRAD -------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWIVGCKTGANRLRGGLPAGWKIGDKTGNNGKDASGDIAVVWPKPDVPILIAAYTQG -GRPNAAQIEAVFARVGRMVAE-- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BEE903 ---TFQQSLAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRRDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter portus TaxID=2676234 RepID=UPI000D6E5A41 --------FDDLARKFYGGIGLSALDTGSGRRI-DFDAISRYAMCSTFKLPLAGMVLALND -AGKLRLDERIGFGPDDLVPYAPFIERQMDRGATLAELCQAAVTVSDNVAANLLLRRIGGP -QAFTQWLRGVGDTTTRLDRIEPDLNSNLPGDSRDTTTPGAMLDTVNRLVLGDALTPASRG -QLAQWMVACETGDNRLRAGVPSEWRVGDKTGTSTNGASNDVAIIWPPERAPILIACFINC -DTVTARDRDAAHAKVADRILTEf ->[subseq from] Beta-lactamase n=1 Tax=Rubellimicrobium roseum TaxID=687525 RepID=A0A5C4NBJ2_9RHOB ----LDTAMADLEARSRGRLGVAILESGSGMTY-AWRGMERFRMASTFKALLAGAVLRRVD -QGQESLAREVEVRPEDLVEYAPVVEPMVGQSLTVGALCEGTVTLSDNAAANLLLDSMGGP -EGFTAILREIGDEVTRLDRREPDLNTGTPDDPRDTSTPLAYLATLQRMLLGNALSTAGRE -QLLAWLVANKTGDDRIRAGVPEGWTVGDKTGTSGQGDIHDIAVLVPPKGVPILVVAFLSE -TDQPIEEMNGIHAEIGALAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02009 TaxID=1703938 RepID=UPI000B059C68 ---DLLARLRELEERHSARLGVFAHDVRSGRSV-AYRADEHFPMCSVFKTFAVAAVLRDLD -RDGSFLARRIRYTAADVERWSPKTEENLAHGMTVAELCDATLRFSDNTAANLLLRELGGP -TAVTRFARSIGDRTTRLDRWEPELNSAEPWRRTDTTTPRAAGRSYGRLLLGDALPVEDRE -RLTAWMLGNTTSGERFRKGLPADWILADKTGGGRYGGNNDAGVTWPPDGGPIVLTVLTTR -FVEDAAPVDPLVADAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI00099BEF2E ---DVTARLRALEERYDARLGVFAHRPSTGRSV-RYRADERFPMCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEDDLVMGSDQTKAHLAEGMTIAGLAEVAITHSDNTAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPELNTAEPWRLTDTTSPYAVGRTYGRLVLGDALNRRDRE -LLTHWLLSNTTSVNRFHAGLPKTWAIADKTGSGSYGTANDVGVTWTDNGDPIVLSVLSTM -PAPDAVRDDALVADAAAVIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangzhouense TaxID=1325095 RepID=UPI001009C98F -------ELESYERESGGKIGVYAENLATGAQL-AWRADERFVMCSTFKASLAACVLTRVD -RGEDKLAAMIPYGKADLLDYAPVAKQNLSAGMSVADICKAAVELSDNTCANLLLARIGGP -AALTTFWRSIGDTISRLDHIEPELNRSPPGDVRDTTTPAAMAGNLKRLVAGEALSPASRA -QLTEWMVGCKTGANRLRGGLPKAWKIGDKTGNNGKDASGDIAVAWPKLDAPILIAAYTQG -GTPNPTQLEAVFASIGRRVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces fragilis TaxID=67301 RepID=UPI000D5964C9 ----AATRLDALERQHGARIGVFARNLRTGATV-RHRSDERFPVLSVFKTLAAAAVLRDRD -TDGTFLDRRIHYTEAQLVENSDVCRANLATGMTIRELCAAAVQWSDNTAGNLLLRQIGGP -HGITRFARSLGDPVTRLDRWEPELNSGEPWRRTDTTAPAAIAATYARLVLGDGLGRGDRE -QLTSWLLGNRTGDRRLRAGLPPQWTVADKTGAAGYASLNDVAVVWTEDGTPLVMAVLTTK -PERDAVRQDVLLEETARVLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium canariense TaxID=255045 RepID=UPI000A1946E7 ---DAQPELETYERESGGRIGVYAENLATGARL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIPYGKADLLEYAPVAKQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTASRLDHNEPELNRPPLGDPRDTTTPAAMAGNLRRLLTGEALSATSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIATYTQG -GTPSAAQIEAVFARIGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sacchari TaxID=115433 RepID=A0A1I3Q359_9PSEU ---TAAPDFHDLETRFGARLGVYALDTGSGKEI-AYHAEDRFAYASTIKALAVGALLLQGA -----DLDKRLTYTQADIVSHSPVTGPRVNTGVTVREAAEAALQQSDNTAGNLLFRELGGP -AGLANALRSIGDTTTHPDRWETSLNEAAPGDIRDTSTPRALATSLRAFALGDALPADKRD -LLVDLMRHNTTGSGLIAAGLPEGWTSADKTGSAGYGTRNDIAVVWPPSSAPVVLAVLSTR -DTKDATYDDKLIAEATARAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR9_STEMA ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPETNSFAEGDPRDTTTPAAMAGSLQRVVLGKALQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3N0K7_MYCAS ---DLSRRFGDLERRYGGRVGVYVPETATTTAL-AYRADERFAFCSTFKAPLVAAVLHQYP ---LAHLDTLVTYTRSDINSTSPVTEQHVGSGMTVRQLCDAAIRHSDGTAANLLLSQIGGP -AGFTGYLRGLGDGVSRLDQAEPELNRDAPTDDRDTTTPRAMASVFQQLVLGDALPADKRT -LLVDWMMRNTTGDNRIRAAFP-DWKVADKTGSGDYGRTNDVAVAWSPGGVPHVIAIYSDC -TAYDAQPDEAVVADAARIVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinobacteria bacterium OV320 TaxID=1592329 RepID=UPI0009EBA829 ----VTERLRDLEAGHGARLGVFAYNVRTGRSV-RYRAAERFPVCSLFKTLAVAAVLRDLP ---EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP -TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR -RLTDWMLGTITSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWTPDGAPVVLAVQLTK -PDREAAYDNELIVKTAEVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0ULS1_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLIAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0005B8D3FE ------GDFAALEKACAGRLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPEMNSFAEGDLRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces glaucescens TaxID=1907 RepID=A0A089X3A0_STRGA -----TGRLRALEREYGAKLGVYAHNVGTGRTI-RHHADDLFPICSLFKTLAAAAVLRDLD -RDGEFLARRIHYTEADLVDGSDETRKHLAEGMTVAELCDVTIRYSDNAAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYARLVLGDALPGADRE -LLGHWLLNNTTSSDRLRAGVPPTWTVADKTGGGDYGVNNNVGVAWTPDGTPVVLAVLSRM -FDPAAVRDNTLIARTAKVLTD-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Methyloumidiphilus alinensis TaxID=2202197 RepID=A0A2W4T6X0_9GAMM ----VKARLRTLEAAAHGRLGVHILDTSTGQEY-GYRSDERFMLLSTFKLLASAFVLHRVD -AGQESIVRRISYTQADLIAWSPITEKHADGSMTLSELCEAAVTASDNTAANLILSSYGGA -PALTAFMRRLGDGVTRLDRKEPELNFKGANGLWDTTSPRAMVYTLKKVVLGNELSSTSRD -QLQQWLLNNTTGGRRLKAGLPASWRIGEKTGTNRK-GANDIGVIWPPNRAPIVVAAYLND -SLASAEIKESTLAAVGKLVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Dyella ginsengisoli TaxID=363848 RepID=UPI00036E824D ------DAFAALEKGHGGRLGVAVLDTGSGKRL-LHRADERFLLCSTGKLLAVAAVLARVD -RGEERLDRRIVFRREDVLDWAPVTRLRPGPPMTIEELCQAAMIVSDNTAMNLLLASLGGP -ATLTRFVHGLGDPLTRFDRTEPSLNRPGPGGFEDTTTPLAMLDDMRRVLLGDVLSPASRE -RLLDWLRHNTTGTTQLRAGLPAGWTAGDKTGASQT-QNNDVAIVWPPGRAPVLIAAYYES -SAGAGDARKSVLAQVGALAA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000810D999 -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLIAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces bauhiniae TaxID=2340725 RepID=UPI0013BF9A2E ---ALRPELAALEKRYGARLGVYAHNTRTGTTV-AYRADEPFAMCSTFKAIAAAAVLRDFG --GRAALGEVIHYPPADILSSSEHTKARQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSQGDRE -QLVGWLRGNTTSTHRFGAGLPSGWVLADKTGTGSYATANDLGVAWTGRGTPLLLSVLSTK -PEPDAPVDEALIEETARLLA--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium sp. E802 TaxID=1834152 RepID=A0A1A2LBI4_9MYCO ----VDDQIAELERRHNLLVGLYAENLDTRRRV-THRPDDMFAMCSTFKAYAVARVLQLVE -HGQLSLDHRVFVDPQAIVSNSPVTETHAGAEMTMGELCQAALQRSDNTAANLLLKAIGGP -AAVTEFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILTGDALSPRQRR -QLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAYGPDGQRILLVMLTRS -QADDAENQRAVIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E2559F0 -----DAEFTRLEEEFGARLGVHALDTGTGQAV-EFRADERFAHCSTYKVLAFGAVLDRTP ---VDELDRVVTFSGADLVFHSPVARERVSTGMTLRELGDAALRHSDNTAANLLLAELGGP -EGLTEALRGIGDDVTRVDRFAPEMAQAVPGDDRDTSTPRAMAASLRAFALGEVLPEDRRA -VLVDMMRSNTTGDDLIRAGAPEGWAVGDKTGACGYGTRHDIGVLWPPEGDPVVLAVMSSR -DEAGAGYDDALVARATEVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=UPI0008536456 ---AVEAELAALEAEFGGRLGVYAVDTGSGNSI-GHRAQERFLLCSTAKVLAVAAVLRLRV -TEPELMERVVQYDQSQVLEYAPVTAQHVADGMTVSALCDAAITVSDNTAMNLLMELVGGP -DGVTDFCRSLGDEHTRVDRMEPELNVGAPGDERDTSTPEQMAVDLRELALGAGLDETGRE -LLVGWLRANTTGDEQIRAGLPADWQVGDKTGSGSLGEINDIAVVWPPEADPWVIAVYTAP -DDPESTTGRATVAAATAIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodobiaceae bacterium TaxID=2026785 RepID=A0A2E5BUS5_9RHIZ ---TLLETVRKIEHRSNGQLGIAIHDTGLDRHW-YYKADERFPLSSTFKPFACAGLLSKMD -KGEEHLDRRLIVHSEDIVTYSPVTANHIGPPLSLSQLCEATITLSDNTAGNFVLKALGGP -TGFTAYMQSIGDKTTRLDRWETALNEAHPGDAQDTTTPRAAMTSLTTLLLGEALSPASRD -RLTGWMRNDKVADALLRASLPQNWEIADKTGAGNNGSRGIIAVIWPPAQAPLIVAIYMTG -TSFSLEERNTAIAEIGHALVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0007659290 ----LSRQLAELEREYAARLGVYAHDTATGRTV-AHRADERFPICSVFKTLAAGAVLRDLD -RDGEYLAKRIHYTKEYAEAYSPITATNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP -SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE -LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK -HDPAGPTDNPLVARAAGLVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID10853 TaxID=2706028 RepID=A0A6B2RRU3_9ACTN ----AAPALKKLEHRYGARLGVYALDTGSGRTI-GYRADERFAYASTYKAPAAAVLLRTAS ---DADLDHVITYRAADLQDYSPVTRPHLSTGMTLRALINAALRYSDNTAANLLLDRIGGP -KALQRALRGLGDTTTHVDRPEPDVNTAVPGDVRDTSTPRALGTDLRGFALGGLLPAKRRD -ELNTMLLHNTTGGPYIRAGAPAGWKVGDKTGNGGYGTRNDIAVLRPPHGSPVVLAVLSDR -GRQNATSDDALIADATKATL--- ->[subseq from] Beta-lactamase n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=A0A1D8BXR9_9PSEU ---AVEAELAALEAEFGGRLGVYAVDTGSGNSI-GHRAQERFLLCSTAKVLAVAAVLRLRV -TEPELMERVVQYDQSQVLEYAPVTAQHVADGMTVSALCDAAITVSDNTAMNLLMELVGGP -DGVTDFCRSLGDEHTRVDRMEPELNVGAPGDERDTSTPEQMAVDLRELALGAGLDETGRE -LLVGWLRANTTGDEQIRAGLPADWQVGDKTGSGSLGEINDIAVVWPPEADPWVIAVYTAP -DDPESTTGRATVAAATAIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. AC460 TaxID=1282360 RepID=V4NZK0_9CAUL -----AAAMLDITKRHGGRIGVSAIDAGSGGRL-SVSSQERFGMMSVFKWILAAAVLARVD -KGELKLDQVVRFGRKDLVGWSPVTEKKVKDGITVGELCAATVSKSDNAAANLLLPLVGGP -EGLTKWIRSLGDGVTRVDRKEPEMNNVAEGDPRDTTTPEAMTQLLQIVFTGAALEAASIK -QLREWMVATSTGDKRIRAGVPSGWTVADKTGTAN-GAVNDVAVIWPKSEGPIFLSIFTVG -GTLEPEAKEQVVADIARLVCDVf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AW19M42 TaxID=1379686 RepID=UPI000463E07F ---RTAQAFRDLERKFDARLGVHTLDTGSGRTV-THRPDERFAYASTCKALLVGAVLDKNS ---LRQMDRLVRYGRDDLVSASPVTERHIATGMTLRELSDAAIRYSDNTAANLLFHELGSP -RALQGALRALGDDVTRCDRYETALSDATPGDLRDTSTPRALATGLRAYVLGTTLPADKRA -VLTDLLRRNTTGDNTIRAGVPDHWQVGDKTGTGGYGTRNDIAVIWPPGAAPITLAVLSRR -DAKDAERDDALIAGAAKVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Dyella soli TaxID=522319 RepID=A0A4R0Z0S3_9GAMM -----QDKFADLERRFGGRLGVAIHDLETGQKA-GHRQDERFLMCSTFKLLEAAAILARVD -KGAESLDRRIVFGPDVLLSHAPITRQHAGGEMTVGELCQAAITVSDNTAANLLLESLGGL -MAFNGFLRSLGDHVTRLDRNEPTLNVA--HGDLDTTSPKAMLGSVEKVMLGDALSPASRE -QLAAWMKQTTTGLTAIRAGLPPAWLAGDKTGRGSHGETNDITLAWPPGRKPVLIVAYYAH -PDVSDDVRSHVLAEIGRMVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. CCH5-F6 TaxID=1768753 RepID=UPI00076A41E6 -------EFAAYERESGGRIGVHAENLATGAKL-AWRADDRFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGQADLLEYAPVARQNLAASMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSRPGDSRDTTTPAAMAGNLRRLVLGEALSPASRV -QLTEWMVNCRTGANRLRGGLPADWKIGDKTGYNGKDAAGDIAVAWPKPDTPILITAYVQG -GTPTAAQIASVFAQTGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. XY511 TaxID=1519480 RepID=UPI0006B00568 -----VRRLRALEAEYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVSELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. PID17_43 TaxID=1583451 RepID=UPI000BFFEAA1 ---QLNEDLAAIEQHIAGRIGVTVWDTQTDQRW-DYRGDERFPMMSTFKTLACATMLNDMD -SGKLDKNATAKVEERDIVVWSPVMDRMTGQTTRVEHVCEAAMLMSDNTAANIVLRSVGGP -RAVTLFLRSIGDKATRLDRYEPGLNEATPGDKQDTTTPNAMVNTLHTLLEGEALSYESRT -QLKIWMQDNKVSDSLMRSVLPKDWSIADRSGAGGFGSRGITAMIWKENHKPVFISIYITE -TDLSLQARDQVIAKISQLVLEEy ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. MMS16-BH015 TaxID=2018025 RepID=A0A2H5BA97_9ACTN ---DLDHRLSALEQRHSARLGVFAQDTGTGRTV-RYRAEELFPFCSTFKTIAVAAVLRDLD -RDGTYLAKVIRYSEQEVKAYAPITGQNLANGMAVADLCAAAIRYSDNCAANLLLRELGGP -TAVTRFCRSVGDRTTRLDRWEPALNSAEPGRVTDTSSPAALGRTYARLTLGDALDAPDRA -RLTDWLKGNTTSTHRFRAGLPESWTLADKTGTGDYGTTNDAGLTWPPGRAPIVLTVLATK -QDQAAPADEPLIAATAALLAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALC7_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVXLLGPNNKA---------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium 14-68-21 TaxID=1970612 RepID=A0A259R2T8_9GAMM ---DAADAFAALERRHGGRLGVAVLDTGSGRRL-LHRADERFLMCSTGKLLAVAAVLARVD -RGEERLDRRITFRPDDVLEWAPVTRLRVGPPMTVAELCHAAITVSDNTAMNLLLASLGGP -ARLTRFVRGLGDPLTRFDRTEPSLNVPGPQGIEDSTTPVAMLDDMHRVLLGDVLSPVSRE -QLLDWLRHNTTGTQQLRAGLPAGWTAGDKTGASQT-QNNDVAIAWPPGRAPVLITAFYEG -PAGATEARKAVLARVGTLA---- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea maritima TaxID=683260 RepID=A0A1G9FV38_9ACTN --eRVKKELRDLERQLGVRIGAYVIDGGTGQAL-AYRSGERFPLTSTFKAVAAAAVLHKAR -TDPGLMDRVVKWSAAEVKPNSPITEQHVKDGMTIAQLCHAAITRSDNTAGNMLLKQIGGP -AGLTRYFRTLKDPVSRLDRWETDLNSWSPKERRDTTTPAAIARDLRQLTAGDALSAKDRE -RLNGWLKANTTGGARIRAGLPASWTVGDKTGTGGYGTANDIAVAWPRKGAPVIMAIYTNG -RTADAATQDKAVADAARILA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000C06B10F -----EQAFGGLERKFDARVGVYAVDTGSGVTV-THRPDERFAYASTCKALMAGALLKTRP ---LPQLDRRVRYGPDDLVANSPVAERHVDTGLTLRELCEAAVRYSDNAAANLLFHELGGP -RGLRDALVALGDRTTRCDRIEPDLSEAAPGDVRDTSTPRALASDLRAYTLGGALGTDARA -VLNDWLERNTTGDALIRAGAPAGWVVGDKTGTGGYGTRNDIAVVRPPGSAPIVLAVLSRR -DTRGAEPQDALVAEAARVALDAf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. SGAir0471 TaxID=2070337 RepID=A0A4P8SWY1_9MICO ---ATSRAFAALEEQYGARVGVVAINTADGSSL-GYRADERFAFASTNKAFIAAAVLDASS ---ADDLDDVVHYDRSDLLSYAPVTSLHVDEGMTVRALVDAALRQSDNTAANLLVERLGGV -GGVSRFLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSATDLRAVLLGDALDPDDRA -LLRSAMAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVEPPGRDPIVLVVFTTR -DGADDESSDALVAAATRVAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. KBS0715 TaxID=1179671 RepID=A0A554N666_9MICO ---ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGERFAFASTVKVFIAAAVLGASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTRVDRVEPDLNEATPGDRRDTTTPERFAADLGTVLLGDALDATDRR -VLREAMLGNTTGDATIRAGVDPSWQVADKTGTASSGVRNDIAIVTPPGRAPIVLVVMTSR -ADPGAEPSDALVAAATRVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Actinoallomurus bryophytorum TaxID=1490222 RepID=A0A543CC21_9ACTN -------ALARIEHRYHARLGVYAVDTGTGRTV-AYRADERFAYASTFKALAAGILLEHTT ---ARRLDQVVRYRESDLLEYAPITSEHVRTGMRVRDLIAAALRYSDNTAANLVMARIGGP -HAVQAGLRRLGDTTTHVDRTEPSLNEATPGDIRDTSTPRALGTDLRRFVLGDVLPVSRRK -PLTGWLVTNTTGGPYIRAGVPSGWKVGDKTGNGGYGTRDDIAIAWPPGGAPVVIAVQSDR -GVKDAPSDDALIADATKAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DED861 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---PTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DAC6CB ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGDDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xenorhabdus nematophila TaxID=628 RepID=UPI000DE94490 -----------LEKNANGHLGAVLINTADHSTI-AYRADQRFPLCSTSKLMAVSALLKRSE -TNDHLLNQQAHYQQSDLVEYSPITEKHLKSGMTLGELSAATLQYSDNAAMNLILNQLGGP -HEVTKFARTLGDNSFRLDRKEPELNNVIPGDERDTSTPRAMADDLYHLVLGNALDATQRE -QLITWLKGNTTGAASIRAGVPEGWIVGDKTGRCDYGSTNDIAVIWPVNQPPLILVTYFTQ -PDKEASARPDVLAAAARIMTQH- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2Y9UA04_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVGMGEVLKPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Agreia pratensis TaxID=150121 RepID=A0A1X7JDE5_9MICO -------AFAELEQEFDARLGVYALDPDSRAEV-AYRADERFAYASTFKALAVGILLKTVP ---DDQLDQLVTYDASELLPNSPVTEANVDSGMTLRAVAEAAVRFSDNTAGNIVLEKLGGP -EGFTQALRELGDTTTSSDRIETDLNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQA -QLIDWMTGNATGAELIAAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR -PAEDADYDNALIARAAEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_021 TaxID=2175639 RepID=A0A2W1W7A8_9MICO ---ATARAFAALERRYDARLGIAAVDTGSGRTI-VHRAGERFAFASTVKVFIAAAVLDASS ---DADLAIVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -NAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSR -ADPGAEPSDALVAAATRAAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA78_KLEPN -----------------GRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVISC-- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus hibiscisoli TaxID=2023261 RepID=A0A4U0QTB5_9RHOB ---TIAQAARAIETELGGRVGVALRRQGDAQVT-GYRPDERFPLSSTFKAPLCGAILTLVD -AGADQLDRPIGYTSADLVEYSPVTSTHD--AMTVGALCEATITLSDNTAANLLLDRLGGP -EDFTAYLRAIGDDTTRLDRRETALNEAAPGDPRDSSTPAAMTATLDRLLFGPILSAASRD -QLEAWMRADQVADDLLRASLPQGWIIGDKTGAGGFGSRSIVAVIRPPQGAPWLAAVYLTG -NEADMPTRNRAIARIGAAIVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID12488 TaxID=2706040 RepID=UPI0013D94CEE ---DVTARLHALETQHGASVGVFAHNLGTRKTI-RHRADERFPVCSLFKTLAAAAVLRDLD -RVGEVLSKRVHYTTDDLVDGSKQTEEHLAEGMTVAELADAAIRFSDNTAGNLLLRELGGP -GAITRFARSLGDRATRLDRWETELNSAEPWRITDTTTPYAIGRTYARLVLGDALNRPDRE -LLTHWLLNNTTSGNRFRLTLPPTWTIADKTGAGSYGTNNNVGIAWTQDGTPIILAVQTTK -PDRDAAADHPLVAETARVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_034 TaxID=2175623 RepID=UPI000DA8AB84 ---ATARAFAALERRSDARLGVAAIDTGSGRKI-AHRAGERFAFASTIKVFIAAAVLGASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAAGRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDELVAAATRTAV--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000709EADE -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDVDLLSHAPVTRRHAGKNMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPWVLTAYLQA -GAISYEQQAVVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora echinaurantiaca TaxID=47857 RepID=A0A1C5HDF0_9ACTN -----HHRLTELERRYDARLGVYALATGTGTTI-AHRADERFAFCSTFKGLAAAAVLHANP ---LSHLDTVVRYTEHDLMKSSAITRRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -ARLTAYLRGLGDPVTRMDRIEPDIVTAIPGDPRDTTSPRAIGADYQQIVLGDALPPDKRA -FLRGLLERNATGARRVRAGVPKGWTVADKTGTGDYGTLNDIALVWPPGSAPLVISIMSSK -ATRDAAYDQALIAEAAAYVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Methylobacterium sp. WL119 TaxID=2603888 RepID=A0A5C8VVV4_9RHIZ ----ATDTLREIERRVGGRLGVSVGRSNGPPLL-GHRADERFPMCSTFKVLAAAALMARVD -AGTESLDRTLPYGEGDLLKYAPVTRKALEAAISVADACAAAVEWSDNTAANLMLNALGGP -SALTGWLRGIGDRTTRLDRTEPDLNTAIPDDPRDTTTPDAMRTTLERVLVGTVLSPATRT -RLDGWMVAGQTGSKRLRAGIPPDWKVGDKTGSGDNGTYNDVAILSPPGQAPILAAVYLTG -STAPVTDVDAAYAEIGRMIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Clostridium senegalense TaxID=1465809 RepID=UPI00028939AF ---QYNSEFSQLENDYDVKLGVYALDTETGKEV-IYRADDRFAYCSTFKVLVAGSVLKQDT ---LEQLNQVIKYNEEDVISYSPITKNNVEEGMTIEEICKAALQFSDNTAANLLLNHIGGV -SGFKLALNQLGDNVTQPVRIEPELNEAIPGDTKDTSTPRQLAIDLQAYTIGNVLTDDKKK -ILIDWMTGNTTGDTLIRAGAPENWVVADKSGTGPYGIRNDIAVVMPPSKKPIIVAILSTH -DTKEAKHDDKLIAQASKIVFDFf ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase AXC-4 n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5C0PCS7_ALCXX ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycolicibacterium TaxID=2636767 RepID=UPI0012DC8F20 ----VDDQIAELERRHNARIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RGQQSLDHRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAANLLLKTIDGP -AGITAFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDAGIAYGPDGQRLLLVMMTRS -QA-DDPKADNL------------ ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium amphicarpaeae TaxID=1404768 RepID=A0A2U8Q1M2_9BRAD ------AELETYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEKLAATIAYGKADLLEYAPVARQNLAAGMSVSDMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLVVGEALTPASRG -LLTEWMVNCKTGANRLRGGLPAGWTIGDKTGNNGKDASGDIAVAWPRNKTPILITAYTQG -GTPNAAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Terriglobus roseus TaxID=392734 RepID=A0A1H4Q4P2_9BACT ---TLPAAIAAMEKKQGGRIGVSVLDTATRERA-AYRADERFPMCSTFKFLLAAAVLHRVD -TLTDDLRRQVDVPPKPLLGNSPLTEEHAGTSMTLGALCSAILTRSDNTAANVLLETIGGP -NAITTYAKVIGDSVTRLDRTETSLNESLKGDPRDTTSPNAMVHNLQSLLLGDALEPDSRT -QLTDWMQSSTTGLIRLRAKLPKDWRAADRTGSNGEHTTNNIAVLWPAGGAPILVAAYITQ -CPGPEDKRNAMLAEIGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. WMMB499 TaxID=2650775 RepID=A0A5J6UCP6_9ACTN ---AVSRELARLEAKRNLHIGAYAIDTGTGRFV-SHRADRRFPFTSTFKVMACGAVLKKAR -TDPGLMERVIRYTEDDLVDYSPETEKHVGTGMTVSALCDAAITLSDNTAGNLVMEQIGGP -AGLTRFFRSLGDGASRSDRWETALNEWKPGEKRDTTVPRTWAANLRALTVGDALAPADRD -RLIAWMKANTTGDKRIRDGLPDSWTIGDKTGTGGYGNANDIAIAWPDDGAPLVMVVLTTG -KRKDAGADDAAVAETAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A3S0JN13_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RAPALLDTRVPVRAADLLSHAPVTRRHAGKDLTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGSPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=M4Q8X9_9BACT -------EVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGK----------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B87CC ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTRDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens TaxID=29488 RepID=A0A1G5PQH1_PHOLU ---RLATVVKQEEQTLNARIGVAVIDTASDKMV-SYRGNERFPLNSTFKALLCGVLLSEVD -KGKVALTDAIQFDKTELVEYSPVSEKFVVPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP -VAMNLFFSGLGDNVTHLDRYEPELNSAIPGDKRDTTTPVAVSQTLQKLTLGEVLKPSSRQ -QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKDSSPLIVAIYITQ -TEATIAQSNEAIARIGKIL---- ->[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI000B969CA5 ---QLAETVAKTESRLNARVGVVLHDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD -AGTLTLDEELPVLQSDIVSYAPVTEKKVGQSMSLSELCLATIDMSDNTAANLLINRLGGT -EAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLGDVLSPQSRN -QLIEWMSHGGVTGALLRKTAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD -VKADFATRNGALQDISAAVID-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE0DFE8 -----EAQLAALDSKHPGRICVSILDMASGKRI-EHRAGERILMCSTFKALAAALVLARVD -KGEEKLDRRIRYAKSDLVDGSPATKEDAGETMTIAELCAAAVTLSDNTAGNLLLASFGGP -EAITTFCRSMGDEITRLDRTEPTLNYDTPDDQRDTTTASAMLENLRRLLFTDALTAASRS -QLAAWLITNKTGDARLRAGLPKDWLVGDKTGTNGAGNANDIAVLWPANRAPILVTAYCEI -PEIAAGERNAIIAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDEBCA2 -----EAELAALESRHPGRICVSILDMASGTRI-EHRARERILMCSTFKALAAALVLARID -RGQEKLDRRIRYTKSDLVHGSPATKAHLRDSMSVAELCAAAVTLSDNTAGNLLLASFGGP -KALTAFCRSLGDDITRLDRTEPTLNYDRPDDERDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGLPKDWLAGDKTGTNGAGNANDIAVLWPPNRASVIVTAYCEI -PAIAADERNGIVAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. FR26 TaxID=2605987 RepID=UPI00135A20DA -------DFERLEEEFDARLGVYAVDTGTGEEV-SHRPDERFAYASTHKALSAGAVLRRNS ---LEEMEEVVTYTEDDLVSHSPVTERHVETGMTLMEVADAAVRYSDNTAANLLMEELGGP -DGFEEALEAIGDDVTDPERMETELNEGVPGDTRDTSTPRAMATSLREFALGDVLPEDRRD -VFTTMLRGNTTGDTLVRAVVPEGWEVGDRTGAGGYGTRNVIAVVWPPEADPLVIAIMSSR -DREDAEYDDALVAGAAEVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces tirandamycinicus TaxID=2174846 RepID=A0A2S1SY88_9ACTN -----VREFAELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS ---LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDELGGP -RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA -QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGSYGVRNDIAVVWPPDSAPIVMAIMSNG -LRRDADHDDRLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas taiwanensis TaxID=176598 RepID=UPI001389B1E2 ------PDFAALEAASGGRPGGCLLGTARGRGQ-GHRLPERFPMCSTFKALLAAAVLAQAD -QGRLSLDRRLQVRARDLLEHAPVTRRHVGKDLTVRDLCRATMVTSDNTAANLLLQAIGGP -AAVTAFVRALGDGVTRLDRYEPELNLHAPGDPRDTSSPAAMAASLARVVAGEALAPASRQ -QLADWLVDNQTGDACLRAGLGPRWRVGDKTGSDGRGIRNDVAVLWPLGGAPQVLAAFLEG -ARVGAAARDAVLAQAARLA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3P808_MYCAS ---DLNSQFDQLERRYGGRVGVYVPANATTGAI-AYRADERFAFCSTFKAPLVAAVLHQFP ---LAQLDKTITYTKSDINSTSPVTEQHVETGMTVGQLCDAAIRYSDGTAANLLLDQIGGP -SGFTAYLRSLGDNTSRLDQAEPELNRDPPNDERDTTSPHAIALVFQQLVLGDALPADKRA -MLTDWMARNTTGGNRIRAAFATDWKVIDKTGSGDYGRANDVAVVWSPGDVPHVIAIYTDL -VAYDAEPNEAFVADAARIVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1-11 TaxID=2590549 RepID=A0A510TGN0_9ACTN ----LGREFGDLERRYGARLGVYARNARTGRTA-AYRAGEPFAMCSTFKAFAAAAVLRDQA --GCAPLDKVIHYPARDILDNSQYSYDHLATGMTVGEACAAAIQYSDNTAGNLLLRQIGGP -QGLTRFFRSLGDRVSRLDRWETELNTAVPGDPRDTSTPRALGESFERLTLGRALARADRE -QLVTWLKGNTTSGQRFGAGLPAGWVLADKTGTGSYATANDIGVAWTTRQTPVLLTVLSTK -DAEDAPVDNELIRRAAEVLA--- ->[subseq from] Beta-lactamase Axc n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A3G1JAD7_ALCXX ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium tropici TaxID=398 RepID=A0A329Y8Y7_RHITR -----EERLAALESKHPGRICVSILDMASGRRI-EHRAGEHILMCSTFKALAAALVLARVD -KGEEKLDRRIRYSEGDIIGGSPATKLRVGDGMTVAELCAAAVTLSDNAAANLLLASFGGP -KALTAFCRSLGDDLTRLDRTEPTLNYDTPDDQRDTTTAAAMLENLRRLLFTDVLTASSRS -QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWTSKRAPIIVTAYCEI -PSISADERNAVIAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=A0A0L8M7Q2_STRVG ----VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD -HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLSILSTL -PEPTAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5CZZ2_9ACTN ----AVRKLRDLEREHAARLGVFGWNTVTGRSV-LHRAEERFPMCSTFKTLAVGAVLRDLD -HDGTFLSKIIHYTKQDIKRGAPVTGENLAQGMTVEDLCGAAISYSDNTAANLLMERLCGP -TSVTRFCRSIGDSVTRLDRWEPELNSAEPGRVSDTTSPRAIGKTYAQLVLGNALEAGDRK -KLTGWLLANTTGGKRLRAGLHEDWSVGDKTGTGSYGTANDVGIVWPPGQGPIVMAVLSTK -HDADSEADDLLIAHAAAVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes rectilineatus TaxID=113571 RepID=UPI0005F2B126 -------DLGTVEERYGARLGVYAVDTGTGRVV-THRADERFAHASTFKALQAGVVLRIAS ---DADLDRVVTYRKRDLLAHAPITEKHVATGMTVRDLLDASLRYSDNTAANLLFATIDGP -DGLERELRALGDTTTSVDRIEPDLNEAAPGDTRDTSTARALAADLQSLLLGDALTPDRRR -LLDGWMRANTTGGPYIRAGLPDGWTAADKTGAGGYGTRNDIAVLHPPAGSPIVLAVLSRR -TAENAGSADALIAETTKSVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinospica robiniae TaxID=304901 RepID=UPI0012F7F3C5 ------AAFQQLESRYGARLGVYAIDTGTGRSV-AFQADERFAFCSTIKAFAAGELLRRET ---DAQLAQTITYSASDLVDYSPVTSKHVQGGMTLTAVMSAAIEVSDNTALNLMFGRLGGP -AGLQSALRSLGDATTDVDRTEPTINTAVPGAVQDTSTPRALAADLRAFVLGDVLTAGRRA -RLTAWLQANTTGGPYIRAAVPTGWKVGDKTGNGDYGTRNDIAVLWPTHGAPIVIAVLSHR -GTQNASSDDGLIADATKLALQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=UPI0006E1C018 ----LTGRLRELEEEHSARLGVFAHDIRTGRSV-AYRADERFPMCSVFKTLAAAAVLRDLD -HDGSFLARRIRYTAADVERFSPRTGENLAHGMTVAGLCDATLRYSDNTAANLLLRELGGP -TAVTRFARSIGDGVTRLDRWEPELNSGEPWRDTDTTTPRAIGRTYGRLVLGTALTPRDRD -RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGVAWPPTGGPVLLAVLTAK -PEEDAEADNPLVAGAAALVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=M5D2E8_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RRPALLDMRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDALSRSDRLEPELNSFAKDDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIGVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI000A16D746 ---QYNSAFSQLESDYDVKLGIYAFDTEMNKEV-VYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFNHIGGP -SGFKLALNQLGDNVTQPARIEPELNEAIPGDIRDTSTPRQLATDLQAYTTGNILTDDKKR -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQASKIVFDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A1W6AL97_KLEOX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVAXLGPNNKA---------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-241 TaxID=1463896 RepID=UPI0004C12C64 ----VVARLRELEREYGARLGVYARDTATGRTV-VHRADELFPMCSVFKTLAVAAVLRDLD -HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLALGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPLVLSILSTL -PEPTAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. SLBN-2 TaxID=1522278 RepID=A0A543HQD1_9RHIZ ----------GIEAKLGARLGLMVVDTETGRQW-QHRSRERFAMASTFKALACAALLDA-- --GETVQSRSVTIEKQDLQDYSPVTGQRVGSQMTAAELCATTLRTSDNTAANLVLAALGGP -KRVTSFLRSIGDTVTRLDRTEPMVNEAKPGDPRDTTTPESMTQSIGDLVLGDALSADARR -QLTGWMEANEVADRLLRAGVPQDWRIADRTGAGGHGTRGIVAVMWPPQRKPVIAAIYLTE -TDASLAERDAAIAEIGRAIAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2B3H8_STRVZ ----LTGRLRELEEEHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAAAAVLRDLD -HDGSFLAQRIRYTAADVERFSPRTGRNLAGGMTVAGLCDATLRYSDNTAANLLLRELGGP -KAVTRFARSIGDGVTRLDRWEPELNSGEPWRETDITTPRAIGRTYGHLVLGAALTPRDRD -RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGIAWPPTGGPVLLAVLTAK -PEEDAAADNPLVAKAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00061CAC22 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---RTHLDKLLTYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. SC4 TaxID=1793160 RepID=A0A135H462_9NOCA ----LDATIAALEAQYSTRIGVTAVNPVTGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAVGTPMTLGKIAEAALTQSDNTAGNYLLREIGGP -QAVTDFARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGIAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTAADKSGGGGFGTANDAGVAWSPDGAPFVLAILTDS -LTEGAQGNNQAIADTTAAVIE-- ->[subseq from] Beta-lactamase n=1 Tax=Cohaesibacter sp. CAU 1516 TaxID=2576038 RepID=A0A5R8YB63_9RHIZ --qELGETVAAWETKLDGRIGVILRDTASDWTY-SHRSDERFPMASTFKSLLCGAVLGEVD -AGRESLTNQVTYSKKDLVYWSPITKKHLASGLPVSALCEAAVTMSDNAAANLLLKRVNGP -AGLTGFLRGIGDATTRLDRWEPEMSKGTPKDPRDTTSPRAITTSLHNLLFGGALQPASAA -LLKQWMIDDQVADKLIRPHVPDGWIIGDKTGSGGHGTRAIVAFLQTPKGQTFMAAIYITQ -SKAGKDARNQAISAIGRAMIS-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=A0A655AHQ9_MYCTX ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. BIIR7 TaxID=1904462 RepID=A0A1E7RR31_9GAMM ------SDFAALEKASGGRLGVTLLNTATGARV-GHRQDERFPMCSTFKFVLSATVLHLAD -KGTLSLDRRLPARQQEMLSHAPVTKRHVGKDLTVRDLCRATMVTSDNPAANLLLGVVGGP -AGVTAFLRAHGDTVTRNDRLEPEMNDFAPGDPRDTTSPAAMAASLQRFVLGDTLSKPARL -QLADWLIDNETGDARLRAGLSPAWRVGDKTGSNGEDTTNDIAILWPLGGAPWVLTSYLQG -ASVDDAGRNDVLRQVAVI----- ->[subseq from] class A beta-lactamase n=1 Tax=Luteimonas sp. 100069 TaxID=2006109 RepID=UPI000F5166F8 ---TLDAALAALEQAAGGRLGIALFDTGTGRRL-GRREKERFPMCSTFKALLAGAVLHAVE -RGHVRLDQPVDVAAGDLVPYSPYVETRVAQGARVDDLCRATVTLSDNAAANLLLPLVGGT -SGLTAFLRALGDPVTRLDRWEPDLNEAARDDPRDTTSPRAMVDSLQRLLFGDVLRAPLQA -VLAAWLIENRTGEARIRAGVPAGWIVGDKTGTCGAGTAADVAVLYPPARAPLLLAVYVHG -AGVSGPAIDALQADVARAVL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=D2CGR7_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATALSQAE -RMPALLDRRVPVGEADLLSHALVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium vulneris TaxID=547163 RepID=A0A1B9CWL2_9MYCO -----DDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAAGYRQVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDADNLRPLIGELTAAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. X2025 TaxID=2483796 RepID=UPI000FDBDF24 -----AAELDALEERYAARLGVFAVDTGSGATV-EHRADERFAYASTHKALSAAAVLAGSG ---PDRLDDVVRYDASELVAHSPVTEQHVGTGLPLRRIAEAAVRESDNTAGNLLLEELGGP -AGFERTLEALGDDVTVAARRETALNEATPGDPRDTTTPRAFAQVLRAYAVDDALDTPDRR -TLLRWMRGNATGDTLVEAGLPDGWRVADKSGAGGYGTRNDIAVVHPPGRAPIVVAVFSDR -GRPDADYDDRLVANAARAVV--- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI000DD10E4E ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FE0FB8C --hALEARLAELERRHGGRVGVAALNLSTGVRV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIGFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVSLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLSRPSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDTAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509) TaxID=446468 RepID=D7AWL3_NOCDD -----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT ---PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLMEVADAAVRYSDNTAANLLFDELGGP -DGFEGAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVIWPPEGDPIVLAVMSSR -DEEDAEYDNALIAGAAEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter sp. zrk23 TaxID=2711215 RepID=UPI0013E11D83 --------FDDLARKFGGGIGIAALDTGSGRRI-DFDSISRYAMCSTFKLPLAGMILARND -AGVLQLDEEIGFGPDDMVPYAPVTERFLDRGMTIAELCEAAVTLSDNVAANLLLRRIGGP -GAFTQWLRSIGDTTTRLDRIEPALNSNLPGDPRDTTTPGAMLDTVNKLVLGNVLAPASRA -GLAQWAVACETGDNRLRAGLPDAWRIGDKTGTSANGAANDVAIVWPPERPPFLIACFIDC -ARVTAAERDAGHAEVARRILREf ->[subseq from] Beta-lactamase n=1 Tax=Jiangella ureilytica TaxID=2530374 RepID=A0A4R4RE27_9ACTN ------SAVLELERTHDVTLGLSATNLATGVRL-AHRPDERFAILSVFKTLLAAAVLDRAD ---EKRLRHRVWYPPADVVVNSPVTAEHIDTGITIAELCDAALRYSDNTAANLLLREIGGP -RGLTAYARSIGDRVTRLDRWEPELNAAVPGDVRDTTTAAAVARSFENLLVGRALRPADRR -RLTGWMLANTTSAARFRAGLPGGWKLADKTGAGDYGTNNDAGVAWNPAGEPIVIVALTRR -NRVDAPKVDAALADAARLVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces scabiei TaxID=1930 RepID=UPI000A3633A2 ----LSRQLAELEREYTARLGVYAHDTATGRTV-THRADERFPICSVFKTLAAGAVLRDLD -RDGEYLAKRIHYTKEYAEAYSPITGTNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP -SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE -LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK -HDPAGPTDNPLVARAAGLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. MA5 TaxID=2508572 RepID=A0A4Q1CQR8_9GAMM -----ATDFAALENACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR -RVPGLLDRRVPVREADLLSHAPMARRHAGKDLTVRDLCRATIISSDNTAANLLFDVVGGP -PAVTAFLRAQGDSVTRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRLVLGDALAPGARQ -QLADWLIDNETGDACLRAGLGARWRVGDKTGSNGEDARNDTAVLWPVGGAPWVITAYLQA -ADISNDQRASVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=UPI00099CD60F ----VVARLRELEREYGARLGVYARDTATGRTV-AHRADELFPMCSVFKTLAVAAVLRDLD -HDGAHLAKRIHYTLQDVTDGGSVTERNIAGGLTVAQLCSAAIAQSDNLAGNLLLRELGGP -TAVTRFCRSLGDRTTRLDRWEPALNSAEPSRVTDTTSPRAIGRTYARLAIGDALDSGDRE -QLNRWLLSNTTSADRLRAGLPKDWAVADKTGAGSYGTNNNVGIAWPPGRPPVVLSILSTL -PEPTAPRDNTLIARTAKLLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella aurantiaca TaxID=2530373 RepID=A0A4R5A6Q0_9ACTN ---ALDPAVRELERAHDVTLGVSARNLATGAWL-AHRAGGRFPILSVFKSIAAAAVLRDLD ---ETRLDHRVWYPPADILLNSAVTAEHLDTGMTVAELCDAAIRYSDNAAGNLLLREIGGP -RGLTAFARSIGDGATRLDRWEIELNSAEPGDERDTSTPAALARTFAGLLTGDLLRPADRR -RLLNWMLANTTSGTRFRAGLPDGWRLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR -AERDAERVDAALADVARLVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_007 TaxID=2175646 RepID=A0A2W1UR06_9MICO ----TARAFAALEEQYDARVGVVAIDTADGTGV-GYRSDERFAFASTNKAFIAAAVLDASS ---GEDLDEVVHYGRGDLLAYAPVTSRYVDEGMTVRALVDAALRESDNTAANLLVERLGGV -DGVTRWLRGIGDDVTRVDRVEPDLNTATPGDPRDTTTPAQSAADLRAVLLGDALDAGHRE -LLRSSMAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVQPPGRDPIVLVVFTAH -DRAGAEPSDALVAAATRVAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000459ED29 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AALTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0006BA0CF6 ------GDFAALEKACAGHLGVTLLDTASSRRV-GHRQDERFPMCSTFKSMLAATVLSQAE -RAPALLDRRVPVREADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTISRSDRLEPEMNSFAEGDPRDTTTPAAMAGSLQRVVLGKVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPRGGAPWVLTAYLQA -GAISNEQRALVLAQVGRIA---- ->[subseq from] Beta-lactamase n=2 Tax=Serratia marcescens TaxID=615 RepID=A0A345IR31_SERMA ---AAAKQIKKLEEDFDGRIGVFAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLALGNVLNAKVKA -IYQNWLKGNTTGDARIRASVPADWVVGDKTGSCGYGTANDYAVIWPKNRAPLIVSIYTTR -KSKDDKHSDKT------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. CCGE532 TaxID=2364272 RepID=A0A387GW27_9RHIZ -----DAQLAVLESKHPGRICVGILDMASGKRI-EHRAGERILMCSTFKALAAALVLTRVD -KGEEKLDRRIRYSEGDIIGGSPATKLHVGDGMTVAELCAAAVTLSDNTAANLLLASFGGP -KALTAFCRSLGDEMTRLDRIEPALNYDTPDDQRDTTTAIAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWPSNRAPILVTAYCEI -PSIAANERNAIIAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=A0A1G7NMH0_9SPHN ----LADLAADLERRIGGRLGVAHFVPRTEMLR-GHRLEQRFPMCSTFKLLAVAAILARVD -GRRDHLDAPVAVREADRVAHAPVTGPHIGGTMTLADLCAAAMQESDNVAANLLLRRLGGP -AGITAYAQSLGDRATRLDRWEPDLNSALPGDPRDTTTPAAMARLAGRILEGDSLRPPSCA -LLRRWMTQTRTGLTRIRAGLPHSWSVGDKTGSGANGTANDVAWFHPPGRDPAILAIFLTD -TQASATARDAVFATIAHHVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=UPI000642545F --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLQVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLCDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKEVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007528A93 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPGDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kiloniella majae TaxID=1938558 RepID=UPI000A279779 -------TVIGLEESIGGRIGVAVYDLQTGQNW-EYRSDEKFPMSSTFKPFACAALLTQNE -RKDETLERMVSVSRDDLVSYSPVIEKYADDGVSLRMSCEATVSISDNTAGNLVLKEIGGP -EGFTKYMRSIGDNTTRLDRWETALNEAQPDDLRDTTSPKAIATSLQKLLLEDALSPEARI -EITNWMLNDQVADDLFRSRLPKEWKIADKTGAGGFGSRGIIAVIWPPSRKAVVASVYMTG -NDADFKTRNAAIAEIGAAIFE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-378 TaxID=1463904 RepID=UPI0004CC73A6 -----VRRLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKTPAAAAVMRDLD -HDGGFLARRIHYTQDDVTSGGSVTGRNVAGGLTVAELCSAAIAQSDNGAANLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLALGDALAPRHRE -LLTRWLVSNTTSGDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPSRPPVELAVLTTM -ADAAAPRQDALLARAAAALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000250B61C ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTRLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_005 TaxID=2175641 RepID=A0A2W1R4Z5_9MICO ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGL -GAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADAGAEPSDALVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. t39 TaxID=1828156 RepID=A0A5Q4TE16_9ACTN -----AREFMALERAFDARLGVYAIDTGTGEEI-AWNDRERFPYASTFKALAAGAVLDEYG ---LRGMDRVIRYTADDLVDGSPVTEKHVATGMTLGELCDAAVRFSDNTAGNLLLGELGGP -GGLDAALEDLGDHVTQMDRIEPELGEWAPGDDRDTSTPRALTHDLRAFVLGNVLKKGERD -RLTTLLRTNTTGGETIRAGVPDTWVVGDKTGTATYGGRNDIAVVWPRGGAPIVMAILSNR -PEKDAEHDNALIARAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Roseovarius lutimaris TaxID=1005928 RepID=A0A1I5B8S4_9RHOB --dALSRSVQDVEARIGGRIGYAMSDLHSGQTW-GYRADDRFPVSSTFKALLCGVILARVD -AGEEALDRLVTFGAGDLVTYSPVTETRLATGMTVGELCKSAVTISDNTAGNLLLATVDGP -EGFTAALRDIGDTTTRLDRWETALNEGAPGDMKDTTTPQAALSTLRALLFGEVLTPTSRR -QLADWMIADAVADDLLRASLPEAWVIGDKSGAGGHGSRSIIAVIWPTPDRPVLAAIYMTE -NDADMPARNAAIAEIGAAMFA-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543E1Q5_9PSEU --------LLELERRFDARLGVYALDTGSGATI-AHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYGEGDLLKSAIVTREHVASGMTIGQLCDAAVRFSDGTAGNLLLRDLGGP -AELTAYTRGLGDTVTRMDRVEPDIVEATPGDPRDTSSPRALGTDYQRIVLDDALPGEARA -FLRDLLERNTTGAERVRAGVPRGWTVADKTGTGDYGTLNDIAIVWPPDRAPLVVSVMSSK -AAQDAPYDQAVIAEAAAFVM--- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=2 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009B9054C ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=2 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009C0ED8E ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. CNS-639 TaxID=1169153 RepID=UPI00037613F3 -----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT ---PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP -DGFEEAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVLWPPEGDPIVLAVMSSR -DEEDAEYDNALIAGAAEVVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Arsenophonus nasoniae TaxID=638 RepID=D2U361_9GAMM ----------KKKKKLNSRIGVAIIDTTDNVTI-SYRGNERFPLNSTFKALLCGRLLHQVD -NGKIVLTESVQFQKEQLVTYSPVTEKFTSPLMNWQQLCSAAISYSDNTAANLIAEKIGGP -ASFTRFLRTIGDSITRLDRFEPELNSAIPGDMRDTTTPVAISQTLQKLVLGDVLQPSSRQ -QLRQWMEDDKVANALLRSVLPTQWKIVDKTGSGDYGSRSIISLVWPENRQPLIIAIYITQ -TKATLAQSNEAIARIGKVIFS-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A4V6PMN0_9MYCO ---DLTSRFTEIERRYQGRLGVYVPASGATPAI-AYRAEERFALCSTFKAPLVAAVLHQYP ---LSYLDQRVTFGKADISSPSPIAEQHINTGMTVGEMCDAAIRYSDNTAANLLLNRIGGP -AGFTAYLRSLGDSTSRLDHAEPELNRDPPGDERDTTTPHAIAVTMQQLVLGDALPQDKRA -MLTEWMARNTTGGKRIRAAFPADWKVSDKTGSGDYGRANDVAVVWSPAGTPHVIAIYTDI -AGYYAQPNEAFVADAARVVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CS081A TaxID=2162709 RepID=A0A2T7JJQ3_9ACTN ----HRREFRALEDAFDARLGVYAIDTGTGREV-AYRDGERFPYASTFKALAAGAVLRKES ---LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELAGP -KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SDREAKPDNRLIARAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 303MFCol5.2 TaxID=1172181 RepID=UPI0009973144 ----VTDRLRDLEAGHGARLGVFAYNVRTGHSV-RYRADERFPVCSLFKTLAVAAVLRDLP ---EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP -TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR -RLTDWMLGTITSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWTPDGAPVVLVVQLTK -PDREAAYDNELIVKTAGVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium guangxiense TaxID=1325115 RepID=UPI001008C035 -------ELEAYERESGGRVGVHAENLATGKKL-GWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAVIPYGKADLLEYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARVGGP -AALTAFWRSLGDSTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGEALSPGSRA -LLTDWMVNCKTGANRLRGGLPAGWTIGDKTGFNGKDAAGDIVVAWPKPDTPILITTYVQG -GAPTAAQIEAVFARIGRMVAE-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0006AC52AB -----ATDFAALEKACAGRLGVTVLDTASGRRI-GHRQDERFPLCSTFKTVLAATVLDQSR -RVPGLLDRRVPVREADLLSHAPVARRHAGKDLTVRDLCRATIITSDNTAANLLFDVVGGP -PAVTAFLRAQGDSVTRSDRLEPELNSFAGGDPRDTTTPAAMAATLQRLVLGDALAQGARQ -QLADWLIDNETGDACLRAGLGAHWRVGDKTGSNGEDARNDTAVLWPVGGAPWVITAYLQA -ADISNDQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardioides albertanoniae TaxID=1175486 RepID=A0A543A1S6_9ACTN -------SIAALEKRHQRRLGVWATNMRTGRTL-AHRADERFPMCSTFKTLLAAQILRDLP ---ARTLQQRLTWDESDVVANSPVTSLTTRNGLTVAQLAEATLTRSDNTAANVLLHLVGGP -SAITGFARSLGDTVTRLDRWEPELNSAIPGDPRDTTSPRAIAQTYTRLLLGDALARADRD -QLTTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYATRNDVGVTWTPDGAPIVIAALTRS -DDPAAQPLDAPLADIAATVCA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sioyaensis TaxID=67364 RepID=A0A4Q1R5B1_9ACTN --dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTAKDVRDYAPVTGTNLARGMTVADLCAAAIAASDNAAGNLLLRELGGP -TAITRFCRSIGDRTTRLDRYEPDLNSAEPWRITDTTSPRAIGQTYARLTLGTALTPKDRK -RLTEWLRATTTGGEKFRAGLPSDWTVADKTAGGKYGTNHDAGLTWPPGGSPIVMAVLTTK -REPDATADNPLIAKTAALLA--- ->[subseq from] IMI-9 n=2 Tax=Enterobacter TaxID=547 RepID=A0A1D8RES1_ENTCL ------DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSVKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHDDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia cowanii TaxID=208223 RepID=UPI00111AE30A --------IARLEEKLHARIGIAVIDTASGKSV-SYRGDERFPLNSTHKALLCGALLSKVD -RGEFALSDTTQFSKETLVDYSPVTSKFVAPKMSWQQVCGAAISYSDNTAANLAAQKLGGP -QKVTAFFAGLGDNVTRLDRKEPELNSAVPGDLQDTTTPLAVSRTLEKLTLCDALKPESRA -QLVQWMKDDKVADALLRASLPSGWKIGDKTGAGAHGSRSIISVVWPKKGQPIIVSVYITQ -TEATLAQSNDAIARIGKSIFE-- ->[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA5C5A2 -----EAVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP -EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. H021 TaxID=1519486 RepID=UPI0006AF71F5 -----VRRLRALEREYGARVGAYARDTGRGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Cohaesibacter intestini TaxID=2211145 RepID=UPI000DEA640A --qELGETVAAWETKLDGRIGVILRDTASDWTY-SHRSDERFPMASTFKSLLCGAVLGEVD -AGRESLTNQVTYSKKDLVYWSPITQKHLASGLPISALCEAAVTMSDNAAANLLLKRVNGP -AGLTGFLRGIGDATTRLDRWEPEMSKGTPKDPRDTTSPRAITTSLHNLLFGGALQPASAA -LLKQWMIDDQVADKLIRPHVPDGWIIGDKTGSGGHGTRAIVAFLQTPKGQTFMAAIYITQ -SKAGKDARNQAISAIGRAMIS-- ->[subseq from] Beta-lactamase n=1 Tax=Histophilus somni TaxID=731 RepID=A0A4Y8QRJ7_HISSO ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Beta-lactamase n=3 Tax=Moellerella wisconsensis TaxID=158849 RepID=A0A485A2M5_9GAMM ----TLDRIKTTEEQLNGKVGYTELDLVSGKILeSYRSKERFPMMSTHKVLLCAAILSRVD -TGQEQLDRRIMYSQHNLDEYSPVTEKHLVDGMTVGELCDAAITMSDNTAANLLLESMGGP -QKLTSFLRKTGDQITRLDRYEPELNEAFPSDERDTTTPESMAQTMRNLFTGKILTPTSQA -KLIDWMEADRVAGQLFRSVLPAGWYIADKSGAGKHGSRGIVALLGPYGKPSRIVIIYMTQ -NEATMNELNRHIADIGNTLIKNw ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5K8C2U2_ALCXX ----FQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDVLKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] ROB family class A beta-lactamase n=1 Tax=Pasteurellaceae TaxID=712 RepID=UPI000E31F4FB ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_045 TaxID=2175629 RepID=UPI000DA8F05B ---ATARAFAALERRYDARLGVVAVDTGDGRTI-AHRAGKRFAFASTIKVFIAAAVLDASS ---DADLATLVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTATPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRAAV--- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus clausii TaxID=79880 RepID=A8RR46_BACCS ------AVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP -EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio jasicida TaxID=766224 RepID=UPI0005EF2C94 ---KLNEDISAIEQHIAGRVGVAIWDTQSNEHW-DYRGDERFPMMSTFKTLACATMLKDMD -SGKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTATNIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=UPI00058EE7D4 ---AAARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR -VLRDAMLGSTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSQ -VDPKADPSDPLVAAATRAVV--- ->[subseq from] ROB family class A beta-lactamase ROB-3 n=8 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A6B9LD83_HAEPR ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JNW TaxID=2170731 RepID=A0A363RNP6_9BURK ---QFAQAMQDLERSVGGRLGVSALNTVTGAAL-GWRQNERFAMCSTFKMLLAAQVLSRVD -AGQDRLDAALTFDRSVLVEHSPVTEKFAGKAMTVDALCDAIMTVSDNGAANLLLERVGGP -ASFTAYMRSLTDPVTRLDRIEPAMSESKPGDVRDTTSPQAMLSSMRALTLGTALSPASRE -RLVGWMEANTTGDHCLRAGAP-GWKVADKTGSGPN-TRNDIGLLWAPGATPILVTTYLTE -CKAEPKARDAALARVAAELVKLw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2799 TaxID=1463844 RepID=UPI0004CC7584 ---ALRPELAALEKRYGARLGVYAHNTRTGAAV-AYRADESFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPTDILSNSEQTKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRE -QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGRGTPLLLSVLSTK -PAPDAAVDEALIEETARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. SK17 TaxID=2057741 RepID=A0A2K8YKQ6_9BRAD ---SIEHRLKDVEVQSRGRLGVALLDTATGKLI-GNRIDQRFAMCSTFKALAVALVLARVD -RGEEQLDRRVVFSERDLVPPSVATQPHVGPGMTVAELCEAAVTVSDSTAANLLLASFGGP -AALTAYLRSLGDPVTRLDRVELDLNIVKPGEQHDTTSPAAMARTLQRLLLGDALSEPSRA -RLTGWMAGAKDATTRLRAGLPQGWRIANKPGTWKGIATNDVGVIWPPGRAPIVVAAYLAD -APTPVATQEAILAEIGRIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPZ5_9BACT ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Beta-lactamase n=1 Tax=Bibersteinia trehalosi USDA-ARS-USMARC-192 TaxID=1171377 RepID=M4R2V5_BIBTR ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Beta-lactamase ROB-1 n=34 Tax=Bacteria TaxID=2 RepID=BLA1_ACTPL ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] class A beta-lactamase n=1 Tax=Polymorphobacter fuscus TaxID=1439888 RepID=UPI001269C98D ---DLAAAVKTAEAASGGRVGLAVHDTATGRRF-SHRGGERFAMASTFKTLLAAAVLARID -AGEDRLDRAIPVAQGDILGNSPFAERRIGRTASVAELAEAAIIYSDNAAANLLLPSVGGP -AGLTAWLRRTGDPVTRLDRNEPTLNEARPGDPRDTSSPDAIAATWQRLLVGPVLTPASRA -LLTGWLVGNTTGDTRLRAGLPKGWRVGDKTGTGRNGSVNDIAIAWPDRTGPVIIASFINE -GTAAAEVLYALHADLARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNS615 TaxID=1169158 RepID=UPI000368A68A -----VREFTELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS ---LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDEMGGP -RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA -QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGGYGVRNDIAVVWPPDSAPIVIAIMSNG -LRRDADHDDRLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. WB9 TaxID=2594007 RepID=A0A516WPF8_9NOCA ----LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLQMTE -DGSTSLDKTVEIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLAREVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVLE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAA3_KLEPN ----------------RGRVGMIEMDLASGRTLtAWRAEERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIT--- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HM190 TaxID=2695266 RepID=UPI00135AE053 -----APAFRELEREFDARLGVYAVDTGTGRSV-AYRADQRFAYASTFKALAAGAVLRKHA -EGGDGMEKVVTYGRDDIVENSPVTEDFVETGMTLSGLCAATLWYSDNTAANLLLDELGGP -DGLERVLEELGDDVTEMDRLEPDLSEGRPGDVRDTSTPRAMAGSLRAFLLGDALERDDRA -LLRTWMETNRTGGTLVRAGVPDGWTVADKSGSAGYGGRNDIAVLWPEDGNPVVLAVLTSR -DKQNAERRDALVARAATAAI--- ->[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA53901 ------AVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP -EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGKALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rubida TaxID=112413 RepID=A0A1I6B3N5_9PSEU -----QPDFAALEKAFDARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRAWSKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYATRNDIAVLWPPHRAPIVLAVLSDR -RQKDAKTDDKLIARAAAAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia oryzae TaxID=497725 RepID=UPI0007DE29A0 ----LAEVVRLQEQQLGARIGVAVVDTASGTTA-SYRGDERFPLNSTHKALLCGALLSQVD -KGELALTDTTQFPRSALVVYSPVTEKFVAPAINWQQLCSAAVSYSDNTAANLLTQKLGGP -AAITRYLQTLGDSVTRMDRFEPELNSAIPGDLRDTTTPLAVSRTLQKLTLGTALKPDSRA -QLIQWMREDKVADTLLRSTLPAGWTIADKTGAGDFGSRSIISVVWPENNTPRIVVIYITN -TKATLKQSNAAIASLGKTIF--- ->[subseq from] Beta-lactamase n=5 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0L8TRZ5_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDKRW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTQFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia amamiensis TaxID=404578 RepID=UPI000A011749 -------RLAELERKFGARLGVYALATGTGVTI-AYRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVVTYTEADLTKNAAITPRHVTTGMTIGQLCDAAIRYSDGTAGNLLLRDLGGP -AELTAYVRSLGDTVTRMDRIEPLITEATPGDPRDTSSPRALGTDYQKIVLADTLPDEKRA -FLRDLLERNATGARRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPPGSAPLVVAIMSSK -ADRDAAYDEALIAEAAAYVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia pneumoniae TaxID=228601 RepID=UPI000314CCFF ------VRLAELERKFDARLGVYALATGTGVTV-AYRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVVSYTEADLTKNAAITPRHVATGMTIGQLCDAAIRYSDGTAGNLLLRDLGGP -AELTAYVRGLGDTVTRMDRIEPLITEATPGDPRDTSSPRALGTDYHKIVLGDALADEKRA -FLRDLLERNATGARRIRAGIPQGWTVADKTGTGDYGTVNDIAIVWPPGSAPLVIAIMSSK -NDRDAAYDEALLAEAAAYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Natronospirillum operossus TaxID=2562806 RepID=A0A4Z0WEX8_9BACT ------SEIERIESHLDARVGFAAYDTESDMRW-EYNSEQRFALASTFKTLACAALLARVD -AGSEQLTRSISVSSSDLVTYSPVLEEYADNRINLSELCEATMTISDNTAANLILQSLGGP -ESVTAFARQLGDDVTRLDRWETELNEAVPGDERDTTTPNAMIGNLEQLLLGNVLTEESIN -LLKTWLINNQVADDLFRSVKPDGWIIGDRTGAGGFGSRAITAVIWPPERKPIFVAFYITE -TTASFEERNAAIEQLGRVLME-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000C1B5FAC ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=W0C0S5_ENTCL ------DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -YEKEAKHEDKVIAEASRIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. H13 TaxID=2605988 RepID=UPI0012387BBC -----ADEFADLEEEFDARLGVYAVDTGTGEEV-AHRPDERFAYCSTHKAFTAALVLQQNT ---PEEMEEVVTYDADDVFGHSPVTGQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP -DGFEEAMEEMGDDVIEADRVEPGLSRWTPGDTRDTSTPRAMAESLREFTLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEDWRVGDKTGNGSYGTRNDIAVLWPPEGDPIVLAVMSSR -ETEDAEYDNALIAGAAEVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4M-K27 TaxID=1927959 RepID=A0A432M684_9GAMM ---DANARLAALERQYGGRLGVAILDTANGSRA-SYRADERFLLCSTFKMLLAAAVLARVD -RGTEQLDKRLEFGKDAVVDHSPVTSLHIGPPMSIAELCKAAVSVTDNTAANVLLKHLGGP -HVITDLARQLGDPLTRLDRYEVELNRPAPDGVSDTTTPNAMLGNLQKLLLGNGLSEASRK -QLTEWMLGAVTGQKLVRAGVPAGWKIAEKTGGGNF-QTNDVAILWPPGRKPLLAAVYYEN -AARDIDERSAVLASVGRIMA--- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus sp. 6R TaxID=1911587 RepID=UPI00090C285A ------EAFRLLEKEYDAKLGIYAMDTGTGKTV-SYRAENRFAYASTHKVLAVGVLLQKMN ---VNQLEETVLIKEDDLVNYNPITEKHVNKLMTWNELSDASMRYSDNTAANYILKRIGGP -AGFKQALRDIGDDVTKPERIEPELNKVKPGETRDTSTPKALATSLQTFTMGDVLTKQKQD -LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGAASYGTRNDIAIIWPPNEDPIILAVLSSR -DEEDAEGNDELIAKATEEVM--- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus opacus TaxID=37919 RepID=K8XNR9_RHOOP ----LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVIK-- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=E0D3G0_RHOOP ----LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium canettii TaxID=78331 RepID=UPI0005B3C881 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPRAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGAGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens UCD-AKU TaxID=1292022 RepID=A0A022LPF9_9MICO ---AAARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR -VLRDAMLGSTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSQ -VDPKADPSDPLVAAATRAVV--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=A0A502C3C3_9MICO ---AAARAFASLERRYDARLGITAVDTGSGRTL-VHRAGERFAFASTVKVFIAAAVLDGSS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELIDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQATPGDRRDTTTPERFAADLRAVLLGDVLDAADRR -VLRDAMLGSTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRAPIVLVVMTSQ -VDPKADPSDPLVAAATRAVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. H021 TaxID=1519486 RepID=A0A0M9Z3R9_9ACTN -----VRRLRALEREYGARVGAYARDTGRGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus sp. LHW52908 TaxID=2303986 RepID=A0A372IYQ8_9ACTN -----EHALAGLEARFDARLGVYAVDTRSGRSI-AHRAYERFAYASTVKVLAAAVVLDRTT ---PAELAQAVPYDSSELVAHSPVTEERLAAGMTLGELAEAALRHSDNTAANLLLDRIGGP -QALDAALAAFGDDVTTVVRDEPELNDTAPGDDRDTSTPRALAADLRAFAVGDALAEEDRA -QLVDWMTGNATGRALVRAGVPADWHVADKSGTAAYGTRNDIAVVYPPEGEPIVVAVMSDR -DLPDDEHDDALVAEPARIVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Kurthia sp. 3B1D TaxID=1562256 RepID=A0A433RUY9_9BACL ----PQQDFKELEKKYDVRLGIYVIDTATNKKI-AYHANERFAFTSTYKALAAGVLLQNAS ---LEQLETVILYTKDDLVAYSPVTELYTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP -KGFEQSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAIDLKKYTIDSTLSIEKRQ -LLLDWMADNKTGDALIRAGVPTDWKVVDKSGAGSYGTRNDIAVVFPPNRAPIVLAILSSR -SEQNATYDNQLIEEATRVIIK-- ->[subseq from] Beta-lactamase n=1 Tax=Photorhabdus luminescens subsp. mexicana TaxID=2100167 RepID=A0A4R4JJQ5_PHOLU ---RLATVVKQEEQTLNARIGVAVIDTASDKMV-SYRGNERFPLNSTFKALLCGVLLSEVD -KGKVALTDAIQFNKTELVEYSPVSEKFVVPAMNWQQLCSAAVSYSDNTAANLIAKKVGGP -VAMNLFFSGLGDNVTHLDRYEPELNSAIPGDKRDTTTPIAVSQTLQKLTLGEVLEPSSRQ -QLVEWMRDDKVADALLRSVLPAGWKIADKTGAGDYGSRSIISIVWPKDSSPLIVAIYITQ -TEATIAQSNEAIARIGKIL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520D439_9BURK ------ESFRRIEAASGGRLGVFMLDTGSGRTL-AYRADERFPMCSTFKFLAAAFVVQRAD -SGLDDLARAVAIPPAELVPYSPVTGPNAGRTMAMAQLCEAAVAVSDNTAANLMLASFGGP -AGLTGFARALGDRVTRLDRNEPLLNEGTPGDERDTTTPAAMAGLMRKLLVDRTLEAASRE -RLQAWLVGNTTGDRQIRAGLPPGWRVGDKTGSGGNGTSNDIAIVWPPDAAPLLVTAYLTG -ATATVAQRQATLAAVGALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora mediocidica TaxID=58352 RepID=UPI00056B1FB2 ---DVTRALGGLEREHGARLGVFARNTATGRTV-LYRADELFPICSVHKTVTAAAVLRDLD -RDGGFLAERIRYTAQDVADYSPITGEHLANGMTVAELCAAALDYSDNTADNLLLRQLGGP -EAITRFCRSIGDRTTRLDRWEPALNSAEPGRVTDTTSPRALGRTFSKLLLGTALSAPDRE -QLTSWLLADTTSAARFRAGLPKDWALADKTGTGDYGTTNDAGIAWTPRRTPLVLSVLSTK -TDSAAPADEPLVAKTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces fulvissimus DSM 40593 TaxID=1303692 RepID=N0CPN8_9ACTN ----TDRAFAGLERKFDARLGVYAVDTGDGRIV-AHRPDERFAYASTCKALLAGAVLAKKS ---LPQMERLVRYGEEEIISNSPITEKHVATGMTLRELCDAAIRYSDNAAANLLFRELGGP -RGLQDALRGLGDRITRCDRYEVALSDATPGDLRDTSTPRALATDLRAYVLGPALPAGKQA -VLADWLKRNTTGDHTIRAGTPRGWEVGDKTGTGGYGTRNDIAIVRPPGGAPIALAVLSRR -DTKDAEPQDALIAGAAKVALEAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. F-3 TaxID=1840095 RepID=A0A170W448_9ACTN -----TGRLRALEEEYGARLGVYARNVRTGRTI-RHRADTLFPICSVFKPLAAAAVLRDLD -RNGEVLSRRIHYTADDLVDNSDRTRENLATGMTIAELCDVAIRWSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRADRS -RLTHWLLHNRTSGTRLRAGLPGTWTVADKTGGGAYATNNNVGIAWTEDGTPLVLAILSRT -FDEDAVQDDTLIARTAAALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia niwae TaxID=626084 RepID=UPI0007A45967 -----HDRLLELERKYDARLGVYARATGTGVIV-AHRADERFAFCSTFKGVAAAAVLQRNP ---RSHLDTVVTYTRDDLLKNASVTPRHLDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP -AELTAFARSLDDTVTRMDRIEPAITEATPGDPRDTTSPRAFGELYHRIVVGDALPSDKRD -FLRDLMERNATGAQRIRAGTPQGWTVADKTGTGDYGTLNDIAIVWPPASAPLIVAVMSSK -AARDAAYDQALLAEAAAYVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0P0G9C0_ECOLX ----------------------------------------RFRMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAS----- ->[subseq from] Beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A317I3D6_9PROT -------ALETYERESGGRVGFYAENLSSGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMIAYGNADLLDYAPVAKENFAKRMSVGDMCKASVEVSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNFRRLALGEALSAASRA -QLTDWMVNCKTGAKRLRAGLPGTWKIGDKTGNNGKDASGDIVVAWPKPDTPILITAYTQG -GTPNAAQIDAVFASIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bryocella elongata TaxID=863522 RepID=A0A1H5ZCR0_9BACT ---DFESEMKTLEGASGGRLGVAMYQPSTGARH-GYRAAERFPMCSTSKLLAVAAMLHVID -REQDHLDRPIIFSKRDIAGYSPATSSKLGPPMTLRELCEAAITLSDNTAMNLLLEELGGP -NAWTAYARTLGDTVSRLDRNEPTLNECRPGDPRDTTTPEAMLADTQKLILGGALSAHSRD -LLTGWMIDCKTGDQKIRAGIPAAWRVGDKTGNSGQGTSNDIAIIWPTGQQPWLLTVYLND -AKVSDAQQSAVSANVARVCV--- ->[subseq from] class A beta-lactamase n=1 Tax=Azoarcus sp. HKLI-1 TaxID=2686016 RepID=UPI0013578CC2 ---ALQARLAGLEAAARGRLGVCILDTESGREH-GYRADERFMMLSSFKLLACALVLHRVD -AGEDSLDRRIVYGREALLPWSPVTEQHADGGMRLAQLCEATITTSDNAAANLILATYGGP -ARLTAYVRALGDDVTRFDRIEPALNLPGDDDALDTTSPRAMVRTMQTLLLGDALSIGSRL -QLQRWLLGSTTGANRLKAGLPSDWKIGDKTGTNQR-DANDIAIVWPPGRPPLLVAAYLAG -SAADGAQKDRTLAAVGALVRDVf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. F001 TaxID=1510026 RepID=A0A4Q6IPE6_9ACTN ----TTAEFRALEREFDARLGVYALDTGTGRSV-GHRADDRFAYASTFKALAAGAVLRKYG ---TDGIDKVVRYSRDDLVENSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLDELGGP -DGLEKVLEEFGDDVTEMDRYETEMSEGTPGDIRDTSTPRAMAGSLRAFLLGDALKRDERE -LLRQWMTTNMTGRTLIRAGVPDDWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVLSTR -DKKDAERRDALLAKAATVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium canettii TaxID=78331 RepID=UPI0002A577E0 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045AE252 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000459EFE3 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=20 Tax=Mycobacterium tuberculosis complex TaxID=77643 RepID=BLAC_MYCBO ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea solani TaxID=1144553 RepID=A0A1H5Z254_9ACTN ---QVKKELRALEASYNGRIGAYAIDTATGRTV-AYRSGERFPLLSTFKAPLCAAALHRAR -TEPGLMDKVVKWTADDLKPNSPTTEKHVEDGLTVAELCEAAITLSDNTAANMVLKQIGGP -AGLTKYFRTLKDPISRLDRWETELNDWTPKERRDTTTPAAIGRDLRALTTGDALDAKDRE -RLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNDAGLANDVAVVWPSGRAPIILAVYTNR -KTAGDPVDDKVIARTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B5CDB ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DB53C3 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=UPI000F4B4482 --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEAAVVLSDNTAANLLLDASGGP -QALTQWLRASGDEITRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWRPQSAPLLVTGYLTE -CPADAPQRDAALAAAGKAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0004684152 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=UPI000B841462 ----AVRKLRDLEREHAARLGVFGWNTVTGRSV-LHRAEERFPMCSTFKTLAVGAVLRDLD -HDGTFLSKIIHYTKQDIKRGAPVTGENLAQGMTVEDLCGAAISYSDNTAANLLMERLCGP -TSVTRFCRSIGDSVTRLDRWEPELNSAEPGRVSDTTSPRAIGKTYAQLVLGNALEAGDRK -KLTGWLLANTTGGKRLRAGLHEDWSVGDKTGTGSYGTANDVGIVWPPGQGPIVMAVLSTK -HDADSEADDLLIAHAAAVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI0004657C99 ----TAADFAALEAASGGRLGVSLLDTATGQAR-GHRQDERFPMCSTFKALLSAAVLAGAD -RGQWSLDRRLPVGEGDLVPHSPVTRRHAGKDLAVRDLCRATMTTSDNAAANLLFGLIGGP -SAMTAFLRANGDTVTRSDRLEPVMNEFALGDPRDTTSPRAMAASMARFAVGEALAAQSRK -QLADWLIDNGTGDACLRAGLGPRWRVGDKTGSNGVDTRNDVAVLWPLGGTPWVLAAYLQG -ATVDSDARDAVLARVARLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanobacillus timonensis TaxID=1926285 RepID=UPI0009BA7AD8 ---QSEEAFKELEDEFDTKLGVYAVDTGTNQTV-SHRAEERFAYASTFKGLAAGAILQNTS ---MDDLEKDMMYSEDDLVPYSPVTENHVEDGMKLKEIMEAAIRYSDNTAGNLLLEELGGP -DGLEEQLREIGDETIEADRMEPDLNEAVPGDTKDTSTPKAFAESLQKYTLSDLLPEEKRE -LLIDWMTGNEAGDTLIRAGVPEDWEVIDKSGAGGYGSRNDIAVVWPSDQAPMVISIFSSR -DTEDADFDDAVVEKAAGLVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Afipia sp. 64-13 TaxID=1895701 RepID=A0A1Q3VZY4_9BRAD --------LKAYERDSGGKIGLHAENVASGKTL-GWRADERFVMCSTFKASLAACVLARVD -RGVDRLDQALSYGEKDLLGYAPVARENLAKAMSLGQMCQGAVELSDNTCANLLLAHLGGP -AALTDFWRSLGDTISRLDHNEPELNNSPPGDPHDTTTPAAMAGNLKRLVLGDTLSPASRR -QLTEWMVNCKTGAKRLRGGLPRHWRIGDKTGNNGKDAVSDIAVVWPKPDTPIIVAVYTQG -GKPNAAQHEQVFAAIGRMVAE-- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0012DDD487 ----FQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDVLKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Serratia liquefaciens TaxID=614 RepID=A0A484X704_SERLI ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLG--------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003A2A515 -----QPDFAALEQAFGARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYGTRNDIAVLWPPHRAPIVLTVLSDR -PQKDAKTDDKLIAQAAAAVVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura syzygii TaxID=1427538 RepID=A0A5D0U4J9_9ACTN --qAVAAKLRALEKARGVRVGAYAVDTGTGSLV-SYRGGERFPFASSFKAMACGAVLRKAD -SDPALMDRVIRYEKSDLSDFSPVTKKHVGTGMSVADLCHATITQSDNTAGNLVLKLIGGP -SGLTAFLRSLGDTSSRSDRAEPGLNHWRPGEQRDTTTPAAWAGDLRALTVGDALARPDRA -RLIGWLKATVTGDERIRAGLPKSWTVGDKTGTAGYGNAVDIAITWPPDRAPLVMAILTTR -PGAGDAADEKAVAETARILAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00082ACE07 -----TGRLRALEEEYGARLGVYARNVRTGRTI-RHRADTLFPICSVFKPLAAAAVLRDLD -RNGEVLSRRIHYTADDLVDNSDRTRENLATGMTIAELCDVAIRWSDNTAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRITDTTSPRAIGRTYARLVLGDALSRADRS -RLTHWLLHNRTSGTRLRAGLPGTWTVADKTGGGAYATNNNVGIAWTEDGTPLVLAILSRT -FDEDAVQDDTLIARTAAALA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429CW20_9PSEU ----ASADFEQLERAFGARVGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---ITELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRRIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -PDKDAEIDNKLLADATAAAMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT302 TaxID=1169155 RepID=UPI00035E5643 -----VREFTELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS ---LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDELGGP -RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA -QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGSYGVRNDIAVVWPPDSAPIVMAIMSNG -LRRDADHDDRLIAEAASVVAD-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. TEPEL TaxID=2283801 RepID=UPI001051B2FB ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RGPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRAAGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACIRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Kurthia sp. 3B1D TaxID=1562256 RepID=UPI000F8E5B67 ----PQQDFKELEKKYDVRLGIYVIDTATNKKI-AYHANERFAFTSTYKALAAGVLLQNAS ---LEQLETVILYTKDDLVAYSPVTELYTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP -KGFEQSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAIDLKKYTIDSTLSIEKRQ -LLLDWMADNKTGDALIRAGVPTDWKVVDKSGAGSYGTRNDIAVVFPPNRAPIVLAILSSR -SEQNATYDNQLIEEATRVIIK-- ->[subseq from] class A beta-lactamase n=2 Tax=Gracilibacillus thailandensis TaxID=563735 RepID=UPI00129CEF1D -----DEEFAQLEDEFEAQLGVYAIDTGKNQIV-EYNPDERFAYASTFKVLAAAILLKQNE ---IKDLEKAVTYSKDDLVTYSPVTENHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -EEFQALLRDLGDDVTEPERYETELNEFIPGNKSDTSTPKVLATNLKKIALEDFLPNDKRE -LLIDWMKGNATGDTLIRAGLPEEWIVGDKSGAASYGTRNDIGIVWPRDREPIIIAVMSRH -DTKDAEYDDELVAKAAGIIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces xiamenensis TaxID=408015 RepID=A0A0F7G0D1_9ACTN ---DPEEDFARLEEEYDVRLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLDEYG ---LAGMDEVIPYGEQDLVPNSPVTEENLPEGMSMSDLCDATVRYSDNTAANLLWDTVGGP -AGLQERLAGLGDDTTRMNRYEPELNEAVPGDERDTSTPRVFAANLGAYVLGEVLPEPERA -QLSEWLITNTTGDELIRAGVGEGWTVGDKTGAGGYGGRNDIAVLWPEDGEPLLLAVYSTR -EEEDAEFDNALIAEAASVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ICN441 TaxID=2558286 RepID=A0A4Y8MM69_9ACTN -----VREFTELEDRFEARLGVYAVDTGTGREV-AHNEDERFAYASTFKVLAAGAVLREHS ---LSGLDQVITYSADDLVPHSPVTAKRVGTGMSLAELCDAAVRLGDNTAANLLLDELGGP -RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA -QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGSYGVRNDIAVVWPPDSAPIVMAIMSNG -LRRDADHDDRLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Neisseriales bacterium TaxID=2053582 RepID=A0A5C8BI81_9NEIS ----YQTKFAQLESSVNGRLGIMAINTANNQQL-EYRGNELFPFCSTGKVMVVGAILKASE -SNPQLMLRQLHYSKQDTESYAPISGQHIKDGMSVSALSQAAIAYSDNGAMNQLLQLLGGP -QAVTSYARSMGDDKFNLVRSEPQLNSAIPGDIRDTTTPTAMAASLQKLVLESSLMLPQQQ -LLQQWLKGNTTGDKRIRAGVPQGWIVGDKTGTGDYGTTNDIAVIWPPHAKPIVIVIYFTQ -DKKDAKPQDEVIAKASKIVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=UPI000421F961 -------EFGAYERESGGRVGLHAENLATGVKL-SWRADERFVMCSTFKASLAACVLARID -RGEEQLAAMIRYGKADLLDYAPVAKQNLAAGMSVADMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDTTSRLDHNEPELNRSLPGNPQDTTTPAAMAGNLRRLVVGEALSPASRA -LLTEWMVNCRTGANRLRGGLPASWTIGDKTGNNGKDAAGDIAVAWPKPDTPILITAYVQG -GAPNAAQIEAVFARIGRMVAE-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUC9_ECOLX ---------------------------ADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSCVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAAAAKI----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces wuyuanensis TaxID=1196353 RepID=A0A1G9W999_9ACTN ---AISRSLTELEQTHSARLGVFARNMRTGRTV-SHRAGELFPMCSVFKTLAVAAVLRDLD -REGEFLAERIRYTAKDTEEYSVITGRNLANGMTVSELCDAAIRHSDNAAANLLLRELGGP -TAVTRFCRSVGDGVTRLDRWEPRLNSAEPWRTEDTTDPRHIAQTYTRLVLGDALSLPDRQ -RLTGWLLGNTTSTERFRAGLPEDWALADKTGAGDYGTNNDVGIAWTPDGTPVVLAVLTTR -RRPDDAGDNRLVARTAELLAD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A3A9FVI1_9BACT ------DAFRLLEEEYDAKLGIYAMDTRTGQTV-SYREEERFAYASTHKVLAVGVLLQKMN ---VDQLEETVLIKEDDLVNYNPITEKHVNKPMTWKELSDASMRYSDNTAANHILKRIGGP -AGFKQALRDIGDDVTKPERIEPELNKVKPGETRDTSTPKALATSLQAFTMGDVLTKQKQD -LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGAASYGTRNDIAIIWPPNEDPIILAVLSSR -DEEDAEGSEELIAKATEDVM--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6ALC2_ECOLX ------EQIKQSESQLSGRVGMIXMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKYLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVXLLGPNNKA---------- ------------------------ ->[subseq from] Class A beta-lactamase PAU-1 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1J0HSJ3_PSEAI ---QMTAVFQQLEAKAQGRLGVHVIDTATGHEF-GYRSDELFMMLSSFKLLASALVLARAD -RGEESLTRRIRYRKQDLVPWSPVTEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP -QALTQYARQLGDKITRLDRNEPDLNTRVEGGSLDTTSPRAMAMTMNKLLLGDALSPLSRN -LLRQWLLENTTGGKRLKAGTPADWTVGDKTGTNKT-DANDIGILLPPQGAPVLVTAYLAD -STASSQIKDATLAEVGRL----- ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4G-K06 TaxID=1927958 RepID=A0A370X0D1_9GAMM ------NAFAALEQRYGGRLGVAVWDTENENRA-GYRADERFLMCSTFKMLLAGAVLSRVD -HGTERLDRRLVFGKDAVLAYAPITSQHAGPPMTIGELCEAAITLSDNTAANVLLTHLGGP -SVVTHLARQLGDTVTRLDHVEPELNRPSADGLSDTTTPNAMLATMHRLLLGDALSLASRQ -QLTAWMLGTVTGKKLVRAGVPADWRIAEKTGSSTR-QTNDVLVMWPPRRKPLLVTAYYDN -PAKDTQARSVVLAEAGRIIA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium nondiastaticum TaxID=35764 RepID=A0A2P7PJS2_9ACTN ---RISRRLSVLEQEHSARLGVFAHNTVTGRTV-LHGADDLFPMCSTFKTVAVAAVLRDLD -RNGEFLAKRIHYTKKEVEDYDKITDEHVANGMTVEELCAAAVSYSDNGAANLLLRELGGP -EAVTRFCRSIGDGKTRLDRWEPALNSAEPGRTTDTTTPRAIGRTYARLVLGNALAPADRK -RLTSWLLANTTSKDRLRKYLPAGWTVADKTGAGSYGTNNDVAVTWSPKGAPVVMSVLTTK -HEATAKGDDDLVAETAKILA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. RF2-non_BP3 TaxID=1637844 RepID=A0A102EY03_9BURK ---AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase class A n=2 Tax=Actinophytocola oryzae TaxID=502181 RepID=A0A4R7VNJ9_9PSEU -------DFGDLEATFGARLGVYAVDTGSGRVV-EHRADERFAFCSTFKALASGALLARIP ---AADLERRVVYTSAELVANSPVSEKHVGDGMTLRELMDAAIRFSDNTAANLIFGELGGP -GGLERELRALGDEVTEMDRVETELSDAVPGDGRDTSTPRALVGDLRAYVLGDALDADDRG -LLTEFLRNNETGDALIRAGVPAGWVVGDKTGTGGYGTRNDIAVLWPPNRSPIVVAILSTR -GVKDAVTDDRLIVAATRKVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Dyella thiooxydans TaxID=445710 RepID=A0A160N3Y4_9GAMM -----ADAFAALERSHGGRLGVAVLDTGSGKRL-LHRADERFLLCSTGKLLAVAAVLARVD -QGEERLDRRIVFRREDVLDWAPVTRSHAGPPMTIEELCQAAMIVSDNTAMNLLLTTLGGP -ARLTRFVHGLGDPLTRFDRPEPSLNVPGPGGFEDTTTPLAMLDDMRQVLLGDVLSPASRG -RLLDWLRHNTTGTAQLRAGLPAGWGAGDKTGASQT-QNNDVAIVWPPGRAPLLIAAYYEG -PELTAEARKAVLAQVGAR----- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangiaceae bacterium YIM 75507 TaxID=2339229 RepID=A0A3A4AYS6_9ACTN -------RYRALERRHGARLGVYALNTATGAVV-AHRAGERFAFCSTFKTLAAAAVLDRYS ---AGGLRKRIRIAADDIDSISPVTRNHVGAGLTLRELCEAAVRHSDGTAADLLVRDLGGP -ARFNAYLRGLGDTVTRLDHYEPELNAMRPGDPRDTTTPEAIAGAYRRLILGDALPEAERA -LLTGWLKRNATGRLRVRAGVPRGWTVADKTGTGRYGRANDVAVVWPPGAPPLVIAVMTDR -PAPAAEPRDALIAQATRRVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces antibioticus TaxID=1890 RepID=A0A1S9NIH3_STRAT ---RLGRRFHALERRYAARLGVYAHDTATGRTL-AYRANERFPLCSVFKTLAAAAVLRDLD -RDGEYLARRIRYTEEYVTAYAPITDENVAAGMTVAELCAATVSHSDNGAGNLLLRELGGP -TAITRFARSLGDPTTRLDRWEPELNTAEPWRRTDITSPRAIGRTYARLLLGGVLPRADRE -LLTGWLVANTTNTARFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPIVLSVLSTK -YAPEGPTDNQLVARAAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0008A8D5E9 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium decipiens TaxID=1430326 RepID=A0A1X2LTJ5_9MYCO ---DLADRFAELERSYQARLGVYVPATDTTAAI-AYRADERFAFCSTFKAPLVAAVLHQNP ---LSHLDTLITYTSADIRSTSPIAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGT -AAFTGYLRSLGDTVSRLDQDEPELNRDPPGDERDTTTPHAIALDFQQLVLGDALPPDKRA -LLTDWMARNTTGTKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGAAHVVAIMSDR -AGYEAEPSQELVADAAKCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. UNPA324 TaxID=1141174 RepID=UPI00114E3C15 -------EFESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARID -RGEEQPTAMIPYGKDDLLEYAPAAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSIGDSASRLDHNEPELNRSPPGNPQDTTTPMAMASNLRRLVVGEALSPASRA -LLRDWMENCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVVWPKPETPILIAAYTQG -GTPKPAQIEAAFARIGRMAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens pv. flaccumfaciens TaxID=138532 RepID=A0A5P8YPA1_9MICO ---ATARAFAALERRYDARLGVAAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -DAVERWLRGIGDRTTSVDRVEPDLNQAVPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRDDIALVTPPGREPVVLVVMTSR -SDAGAEPSDALVAAATSAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429CR28_9PSEU ------ADFEQLERAFGARLGVYAVDTANGREV-AFRADERFAYASTHKVFSAGGVLQRTS ---IADLDRTVTYGQKDVVVNSPVTEKHVGTGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPELNDTAPGDPRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTASYGTRNDIGVVWPPNRAPIVISILTDR -SGKDAKIDNKLLAQATAAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BD1009 -----VRRLRALEAEYGARVGAYARDTGTGRTV-LYRADELFPMCSVFKAPAAAAVMRDLD -RDGEFLARRIHYTQGDVTAGGSVTERNIAGGLTMSELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSDERFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PDAAAPRENALVARAAEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura fibrosa TaxID=111802 RepID=UPI00104198FC ---AVTKQIRALERSRETRIGAFAIDTGTGRYL-GNRADERFAFASTFKAIACGAVLRKAR -RDPGLMDRNVRYTKDDILPNSPETEKHVDTGMTVAELCKATITVSDNTAGNLVLKQIGGP -AGHTAFFRSLGDRVSRQDRWETDLNLWKPGEVRDTTTPRAWAGDLRALTAGDALAPADRA -QLVAWMKATETGGKRIRAGLPASWTVGDKTGTGGYGTANDIAIAYPPSGAPVIFSITTNR -LTADGTADEEAVARTATILA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111FE972 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATVKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Class A beta-lactamase n=1 Tax=Salinicola sp. L3 TaxID=2606937 RepID=A0A640W7E7_9GAMM ---DVQRKLEALEQRHGGRLGVALMNAATGEVA-SLRGDERFLFNSTIKVPIVAAVLARVE -RGEESLDRRIEVSQSDLGGWTPITEKRIGSPMTIAELGQAAVAWSDNAAANLLIESVGGP -ESVTAFLRDIGDDTTRLDRMEPALNEDHEGDERDTTTPLAMMQTLRTLLLGEALSPSMRH -QLASWMIEGKTGDARLRAGMPAGWLIGEKTGTNSVGNANDIGIAWSADRGAVIAVAYAWL -PQASKAQRDQVIAEIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseoluteus TaxID=29306 RepID=UPI0004C1D2F5 ---NLAPRLRELEQLHSARLGVFAHDVRTGRSV-AYRADERFPMCSLFKTVAVAAVLRDLD -HDGTFLARRIRYTKAYVERYSPKTEENLAHGMTVAELCDATLRYSDNAAANLLLRELGGP -TAVTRFARSIGDPTTRLDRWEPELNSGEPWRETDTSSPRAIGRTYGRLVLGDVLAPRDRE -RLTAWMLANTTSGERFRKGLPADWLLADKTGGGRYGGNNDAGVTWPPDGGPIVLAVMTTR -FEEDAAPVNALVADAAALVAA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6PNM4_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLISQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPN------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MP131-18 TaxID=1857892 RepID=A0A1V2RLL9_9ACTN ---SAEEEFRELEREFDARLGVYALDTGTGREV-AFQADERFAYASTFKALAVGAVLQEYG ---LDGMNEVVTYSDDDLIANSPVTENFVDTGMSLRELSAATLWYSDNTAANLLFDALGGP -EGLEAILEEHGDDVTEMDRYEPDLSEGRPGDIRDTSTPQAMAGSLRTFLLGDALDNDERQ -LLRQWMETNTTGETLISAGLPDDWTVADKSGTAGYGGRNNIAVAWPDDGNPIVLAVMSSR -DEENAERDDALIARAASAATE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-2890 TaxID=1463845 RepID=UPI0004CA6D2F ---DPEEDFARLEEEYDVRLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLDEYG ---LAGMDEVIPYGEQDLVPNSPVTEENLPEGMSMSDLCDATVRYSDNTAANLLWDTVGGP -AGLQERLAGLGDDTTRMNRYEPELNEAVPGDERDTSTPRVFAANLGAYVLGEVLPEPERA -QLSEWLITNTTGDELIRAGVGEGWTVGDKTGAGGYGGRNDIAVLWPEDGEPLLLAVYSTR -EEEDAEFDNALIAEAASVAF--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. cf659 TaxID=1761771 RepID=A0A1I3INL4_9BRAD -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGQEQLAAMIPYGQADLLSYAPAAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNRSPPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLIEWMVGCKTGANRLRGGLPARWTIGDKTGNNGKDASGDIAVVWPKSDAPILIAAYTQG -GRPSAAQIEAAFARIGRMVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A344X357_ENTAS ------DEIKNLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFYSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAKHEDKVIAEASRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia inohanensis TaxID=209246 RepID=UPI0012F8E4FE ------DRLRTLEQEHTARVGLAGIDTGTGRSY-AYRGDERFGMGSTFKPLACAALLRAHP -LGTGYFDQLVRFTQDEVVTNSPIAETRVATGMTVRELCDAAITRSDNTAGNQLLKLLGGP -EALTAFLRSIGDQVTRLDRWEPLLNSNIPGDERDTTTPAALAADYRLLVVGDGLAEPERQ -QLTAWLLDNKTGGPRIRAGIPADWKTGDKTGSGDYGVANDVAVTWPAGVAPLVIAVLTTK -TEPGAQADNPLVAAAATIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus G TaxID=1962 RepID=BLAC_STRAL ---DAERRLAGLERASGARLGVYAYDTGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RNGEFLSRRILYTQDDVEQAGPETGKLANAQLTVEELCEVSITASDNCAANLMLRELGGP -AAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPDDWTLGDKTGAGRYGTNNDAGVTWPPGRAPIVLTVLTAK -TEQDAARDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=B5GPE0_STRCL -----HARLRALELEHSARLGVYGLNLATGRSV-LHRADERFPMCSLFKTIAVAAVLRDLD -RDGAFLARRIRYTQADLVEHSPVTPGRLSTGMTVSELCGAAVCRSDNSAANLLLRELGGP -SAVTRFCRSVGDRVTRLDRWEPALNSAEPWRAEDTTSPRAIGRTYTRLVLGPVLDRPDRR -RLTEWLLANTTSGDRFRAGLPGDWRLGDKTGAGEHGTNNDAGIAWKPDGTPVALAVLTTK -REPTAPSDPPLIAKTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. FxanaA7 TaxID=1265492 RepID=UPI0005EDB7D0 ----LSRQLGELEREYSARLGVYAHDTATGRTV-AHRADERFPICSVFKTLAAGAVLRDLD -RDGEYLAKRIHYTKEYAEAYSPITATNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP -SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE -LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK -HDPAGPTDNPLVARAAGLVA--- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase IMI-14 n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=A0A1P8SAH3_9ENTR ------DEIKDLETDFNGRIGVYALDTGSGKSF-SYKANERFPLCSSFKGFLAAAVLKGSQ -DNQLNLNQIVNYNTRSLEFHSPITTKYKDNGMSLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDKDFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKTLALGNILNEREKE -TYQTWLKGNTTGAARIRASVPSDWVVGDKTGSCGYGTANDYAVVWPKNRAPLIISVYTTK -NEKEAMHEDKVIAEASRIAID-- ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. AC466 TaxID=1282362 RepID=V4PEZ7_9CAUL -----AQRMLEIQKRHGGRVGVSALNTEANGSL-SISASERFAMASTFKWVLAAAILQQVD -LGKLKLAQEITYGKKDLLDYAPVTTAQVAKGMTIGDLCSAAVSLSDNTAANLLLPLIGGP -AGLTAFVRAIGDETTRFDRTEPSLNSNIDGDPQDTTTPEAMSTLLRKVYSGDVLKPDSLN -RLKEWMIATTTGKGRISAGVPAGATVAHKTGSGANGAVNDVGVVWLPGKAPVCLSIYTSG -GNLDDAGRDKIIADVTKLVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia oryziphila TaxID=1005667 RepID=A0A1C4CPP1_9ENTR ------NVVHLQEQQLGARIGVAVLDTASSKTV-SYRGDERFPLNSTHKALLCGALLSKVD -KGELALTESTQFPRSALVEYSPITEKFVAPAINWQQLCSAAVSYSDNTAANLLAQKLGGP -AAITQYLQTLGDSVTRLDRVEPELNSAVPGDERDTTTPLAVSRTLQKLTLGTALKPGSRA -QLIQWMREDKVADALLRSTLPAGWTIADKTGAGDFGSRSIISVVWPKNSTPRIVVIYITN -TKATSKQSNAAIASLGKEIF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A105KEM1_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-115 TaxID=1240696 RepID=A0A542HLK1_9ACTN ----VTDRLRDLEAAHGARLGVFAYNVRTGCSV-RYRADERFPVCSLFKTLAVAAVLRDLP ---EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP -TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR -RLTDWMLGTITSANRFRAGLPPTWTVADKTGGGWYGANNDAGIAWTPDGAPVVLVVQLTK -PDREAAYDNELIVKTAGVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseochromogenes TaxID=68214 RepID=A0A1B1AXN0_9ACTN ------PELSDLEQRYGARLGVYARNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLGGHG --DCAPLDNIVHYPPRDILANSPKTEEHLATGMSVGDLCAAAIQYSDNAAGNLLLRQIGGP -DGLTRFFRSLGDRVSRLDRWEPELNTAVPGDPRDTTTPQAIGRGFERLTLGRALDDTDRA -RFIGWLKGNTTSVKRFRAGLPQGWVLGDKTGTGDYASAHDIGVAWTTRNTPVLLAVLSAK -AAKDATVDDALIAETARVLA--- ->[subseq from] Beta-lactamase n=29 Tax=Bacteria TaxID=2 RepID=B1Q1F1_ECOLX ----VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD -KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP -EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK -KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN -THSSMNELNEHIAGIGDSVIKNw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=E2Q8M1_STRCL -----HARLRALELEHSARLGVYGLNLATGRSV-LHRADERFPMCSLFKTIAVAAVLRDLD -RDGAFLARRIRYTQADLVEHSPVTPGRLSTGMTVSELCGAAVCRSDNSAANLLLRELGGP -SAVTRFCRSVGDRVTRLDRWEPALNSAEPWRAEDTTSPRAIGRTYTRLVLGPVLDRPDRR -RLTEWLLANTTSGDRFRAGLPGDWRLGDKTGAGEHGTNNDAGIAWKPDGTPVALAVLTTK -REPTAPSDPPLIAKTAALLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA65_KLEPN ----------------RGRVGMIEMDLASGRTLtAWRADKRFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAAYLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -S---------------------- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0D0I163_STEMA ----TAADFAALEKASGGRLGVTLLDTRTGKRV-GHRQDERFPMCSTIKWMLAAAALHRAD -GQPGFLDERLPMRAEDLIDHAPTTRRHVGKDLSVRDLCRTAMVTSDNPAANLLLRHLGGP -PALTAFMRSHGDAVTRSDRYEPELNRFTPGDPRDTTSPAASAVSLRRFVLGDALRPASRQ -QLADWLIDNETGDATLRAGLGKRWRVGDKTGSNGKDTRNDIGVLWPLGGTAWVLTAYLQG -ASVDSGQRDAVLARVAAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Salinicola sp. CPA62 TaxID=1949082 RepID=UPI000DA13EFB ---SVKRELEALEECHGGRVGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -SGDESLDRRIEVSQSDLGGWTPITEQHLGSPMTVAQLCQAAVAWSDNAAANLLVESAGGP -ERITAFLRGIGDETTRLDRMEPELNEDHESDERDTTTPLAMMQTLRALLMDDALSSASRH -QLAAWMIAGKTGDARLRAGMPAGWLIGEKTGTNGVGNANDIGIAWPGDRGAVIAVAYTYL -PEASKTQRDDVIAEIGRLAAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. RF4-BP95 TaxID=1637845 RepID=UPI000756D83A ---AAQAELAALEKASNGRLGVAALDTASGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGATTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Nitratireductor basaltis TaxID=472175 RepID=A0A084U967_9RHIZ ---RLAEKLAATEREIGGRLGATIIDTHTGRRW-LHRADERFPMNSTFKAFAAAAVLARVD -RGEEDFKRQVPIRREDISNYAPVTERRIGGYMSLFELCEAATTMSDNTAANLITDSLGGP -EGWTQFMRSIGDDVSRLDRKEPDMTEGRPGDPRDTTTPSAITASLQTLTFGDVLQPASRE -QFRRWLLDNKVGQPLFRSVLPSDWVIGDRTGAGGHATRGIVSVIWPAQRRPVLATVYVTQ -TRGRMADRNRAIAGIGTVMVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces clavuligerus TaxID=1901 RepID=Q59830_STRCL ------ADLAALEREHGARLGVYALETGTGAEV-AHRADERFAFCSTFKALAAAAVLHHHP ---IRHLERRVTWTRADVDSISPVTEDHIATGLTVGQLCDAAIRHSDGTAGNLLMRDLGGP -SRLTAYLRGLGDSVSRMDQYEPELNHDPPHDPRDTTTPRAIASDYRKLVLGDALTPDRRA -LLTDWLVRNTTGGRRIRAGVPSGWRVADKTGTGNYGRANDIAVLWPPRSSPLVVAVMSDR -PGFRTPPSERLIAE--------- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI0009EC60C3 ---TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWRIGEKTGTYSKVGCNDAGFAQPSGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces antibioticus TaxID=1890 RepID=UPI0004C4FD4D ---RLGRRFHALERRYAARLGVYAHDTATGRTL-AYRANERFPLCSVFKTLAAAAVLRDLD -RDGEYLARRIRYTEEYVTAYAPITDENVAAGMTVAELCAATVSHSDNGAGNLLLRELGGP -TAITRFARSLGDPTTRLDRWEPELNTAEPWRRTDITSPRAIGRTYARLLLGGVLPRADRE -LLTGWLVANTTNTARFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPIVLSVLSTK -YAPEGPTDNQLVARAAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus patagoniensis TaxID=228576 RepID=UPI0009953FAB --eTLDERLYGLEEEYDARLGLYAVDTGSGQTI-AYQSDERFAYASTHKALAVGALLQQTS ---IEDLDKKIHFTADDLVDYSPITEDNVETGMTLREISDASIRFSDNTAANLIFNEIGGP -KEFKASLRAIGDDVTEPENIETKLNDVKPGETQDTSTAKALTESLRAFALEDVLEEEQRS -LLVEWLKGNTTGDALIRAGVPDGWVVGDKTGSAAYGTRNDIGIIWPPDRAPIVLAVLSSR -DEEGAETNDELIAKATEEIVN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces humi TaxID=1428620 RepID=UPI0006289B06 -----VARLRALEREHRARLGVFAWDTGTGARL-RHRGGELFPMCSVFKTLAVAAVLRDLD ---EDVLAEVVHYDEGDVERGAPVTGRNLASGMTVAQLCAAAVSYSDNTAANLLLEQLGGP -VAVTRLSRSLGDRVTRLDRWEPELNSAEPGRGTDTTSPEAIGATYARLVLGGALDGGDRH -RLTGWLLANTTGGERIRAGLPRDWTVGDKTGTGGYGTANDVAIAWPPGRAPVVVAVLSTH -TDAAAAADSALVSAAAAVVADAf ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0006AC3E51 ----AAADFAALEKACAGCLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAMTLQRVVMGEVLRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ICN19 TaxID=1817406 RepID=A0A5R9EDG4_9ACTN -----SRSLSELEREHTARLGVFARNMRTGRTV-SHRAGELFPMCSVFKTLAVAAVLRDLD -RKGEFLAERIRYTEKDTEEYAVITGRNLARGMTVAELCDAAVRYSDNAAANLLLRELGGP -TAVTRFCRSVGDGVTRLDRWEPHLNSAEPWRVEDTTDPRHIARTYTRLVLGDALSRPDRR -RLTGWLLNNTTSKERFRAGLPDDWTLADKTGGGEYGTNNDVGVAWTPDGTPVVLAVLTTR -QQPDDAADNRLVARTAGLLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alba TaxID=53437 RepID=UPI00034CC8D5 ---DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS ---LEEMERVITYDEDALVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP -EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE -VLVDMLVRNTTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM -EVEDAEPQDSLIAEATEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=UPI0005C263CF ----ASADFEQLERAFGARVGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -PDKDAEIDNKLLADATAAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DCA6A1 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQKP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=UPI00076E3F41 -----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFTAALVLQQNT ---PEEMEEVVTYDADDVFGHSPVTGQHVDTGLPLVEVADAAVRYSDNTAANLLFEELGGP -DGFEEAMEEMGDDVIEADRVEPGLSRWAPGDIRDTSTPRAMAGSLREFVLGDALSEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGNGSYGTRNDIAVLWPPEGDPIVVAVMSSR -DEEDAEYDNALIAGAAEVVVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Blastococcus sp. DSM 44270 TaxID=1938745 RepID=A0A286H3N2_9ACTN ----VAPAFAELEAQFDARLGVYALETGTGRSI-EHRADERFAYASTHKALSAAAVLAAAS ---AADLDQLVPYAADDLVAHSPVTGQHAGAGLPLRDVLEAAVTRSDNTAGNLLLARLGGP -AGFQQALRDLGDATTRSDRTETSLNQGVPGDERDTSTPRALATDLAAYLLGDALDAADRE -LLTGWMRSNVTGATLVAAGVPADWGVADKSGAGGYGTRNDIAVLWPSDGPPIVLAVLSSR -GAADAGYDDALIARAATVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter caenitepidi TaxID=1384459 RepID=A0A0A8K2U7_9RHIZ --nDLARQFAQIEKKVGGRLGVAVS--GAGLKA-ARHGGERFPMCSTFKLLAVAAVLHRVD -EGDETLSREVPVPADAILAYAPVAQQNAGGTMTVSELCEAAMVWSDNTAANLLLESLGGP -EAATAYVRSLGDTVTRIDRMEPDANVFGPGELRDTTTPEAMLGNLQKLFLGDALSPLSRD -RLTEWFVANETGKDRLRAGLPPTWRVGDRTGTGPHGTSNDVAIAWGEAGEPILIAAYLTG -SKADTAARDEALADVGRAI---- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. WSM471 TaxID=319017 RepID=H5YCA1_9BRAD ---DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDELAAMIPYGKADLLEYAPVARQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLLAGEALSATSHA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GTPSAAQIETVFARIGRMVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. AG5470 TaxID=2183903 RepID=UPI001067A2D1 --------VARLEAHLGARIGIAVVDIASGETV-SYRGNERFPLNSTYKALLCGALLSKAD -KGELSLNDTTQFSQSELVEYSPVTSKFVAPAMSWQQLCSAAVSESDNTAANQVTKKLGGP -AAITQFIASSGDSVTRLDRYEPELNSAIPGDLRDTTTPLAVSKTLQKLALGDVLTPRSRA -QLVQWMRDDKVANPLLRSVLPAGWEIGDKTGAGANGSRSIISIVWPQKNKPQIVSIYITE -TNATMAQSNDAIARIGTAIFT-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. CNZ304 TaxID=2512143 RepID=A0A4V6MH24_9ACTN -----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT ---PEEMEEVITYDADDVFGHSPVTEQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP -DGFEEAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVLWPPEGDPIVLAVMSSR -EAEDAEYDNALIAGAAEVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia oryzendophytica TaxID=1005665 RepID=A0A1C4D0B0_9ENTR --------VARLEAHLGARIGIAVVDIASGETV-SYRGNERFPLNSTYKALLCGALLSKAD -KGELSLNDTTQFSQSELVEYSPVTSKFVAPAMSWQQLCSAAVSESDNTAANQVTKKLGGP -AAITQFIASSGDSVTRLDRYEPELNSAIPGDLRDTTTPLAVSKTLQKLALGDVLTPRSRA -QLVQWMRDDKVANPLLRSVLPAGWEIGDKTGAGANGSRSIISIVWPQKNKPQIVSIYITE -TNATMAQSNDAIARIGTAIFT-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. TSA1 TaxID=709803 RepID=A0A2M6UKD6_9BRAD -------ELESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLDYAPVARQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -ATLTAFWRSLGDTTSRLDHNEPELNRSPPGNPQDTTTPAAMAGNLRRLVVGEALTPASRT -QLTEWMVNCKTGANRLRGGLPAGWIVGDKTGNNGKDASGDIAVVWPRDTTPILITAYTQG -GTPNPAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Oleiagrimonas soli TaxID=1543381 RepID=A0A099CXZ0_9GAMM ----IHTRLAALEARHGGRLGVAMLDTSSGLRV-AYRADRRFLMCSTHKVLTVAALLARVD -SGVERLQRRIVFDRDAVLDYAPITRHHVGAPMTLEALCEAAITVSDNTADNLLLETLGGP -SAVTAYARSLGDRETLLVRNEPALNLALPDDPSDTTTPQAMLADLRDLLLGDALRPASRQ -RLLGWMRQCSTGTRLLRAGLPSAWHCADKTGRGAANEINDIGLIEPPKGGPLLVAAYYAG -SIASDEARESVLADVGRLAV--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiales bacterium JOSHI_001 TaxID=864051 RepID=H5WTH6_9BURK -----PAALAALERRSGGRLGVWIEDSATGRVL-AQRADDRFAMCSTFKWLVCAQLLQSVD -RGEARLDQVLPFGKADLVAWSPVTERHAQGALSLAALCQATLTTSDNTAGNLLLARLGGP -AAFTAALRAQGDAVTRLDRVEPDLNRFPPGEERDSSSPRAMAAQLRRFLLGDGLAPGSRQ -QLTDWMQASTTGARRLRAGLPAGWRLATKTGTADDNHTNEVGVLWPPGRAPLVVVAFLAG -SSQPFAQREAVLARVAA------ ->[subseq from] class A beta-lactamase n=1 Tax=Ideonella azotifigens TaxID=513160 RepID=UPI0011424FCB -----SSRFQAIEKASGGHLGVFIQDTATDRRW-GHRADERFLMCSTFKLQATARVLDRVA -RGEERLDRVIAFGKADLAGYSPVTEKAVGRGMTLGELCQATMTHSDNTAANLILASYGGP -ASLTAWMRSLGDDVTRSDRTEPALNEFDATGQFDTTTPRAAAGSLRAVTLGNALPPQQRE -LLVGWMRANTTGGHRLKAGLPAGWTLGDKTGTSDD-CTNDIAVVWPTGGAPVVVTSYIGR -SRTENKLREQCLAQVAGM----- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=UPI00141AC709 ---ATTRALGALESRHDARLGLVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAR ---SDDLDAVVPIEQRDLLAYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP -SVVQRWLRGIGDQVTQVLRVEPDLNEATPGDERDTTTPAQFAADLRTVLLGDALRPDDRQ -LLVETMAGSTTGDATIRAGVPHGWSVADKTGTGSHGVRNDVGIVTPPGGAPVVLVVMTSQ -SAADAEPDDALVATATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura hibisca TaxID=68565 RepID=UPI0009FEA9E8 ----VQKELRRLEASYKARVGAFILDTGTGTSI-GHRVNETFPTASTFKAMAAAAVLDRAR -RDPGLLDRTVHWKKSDEMPNSPLTQGRGEKGMKVAEISRAAITHSDNTAGNLLLKQIGGP -AGLTRFYRSIGDRVTRSDRWEPALNEWKPGEKRDVTTPAAMGRNLQNLVLGKALVSQDRE -RLAGWMRATVTGDNRIRAGVPKGWKVGDKTGTGGYAPANDIAVAWPPSGAPVVIVVYTTR -RDPDAKVEEKLIASTTEVLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. NEAU-AAG5 TaxID=2678616 RepID=UPI0012E319B9 ---AVAKRLNELERTHRARIGAWALDTGTGRVR-THRADERFPFLSTFKAIACGAVLRKAR -RDPGLLDRVIRYTEDDLVPNSPVTEKHVATGMSVADLCHAAITVSDNTAGNLVLRQIGGP -AGHTAFFRSLGDRVSRHDRWETDLNLWSPGERRDTVTPRAWGRDLRELTLGRALVPADRA -RLIGWMKAAETGGARIRAGLPPGWTVGDKTGTGGYGTANDIAIAYPPSGAPLIIVITTNR -RASGGSADEKAIAETAAILAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycetocola saprophilus TaxID=76636 RepID=UPI0009DFA082 ------TAFAALEAEYGARLGLFLIDTGAQRTV-EYRADERFAFASTIKAHQAAAILQTRE ---IAALQEHVTFTAEQIVSYSPITEQHFEDGMLLHEVVTAALQYSDNTAANLMFDRLGGP -SGLQQLLRESGDHTINVDRIEPDLNEATPGDPRDTTTPRAHAHTLARFGISDHLPAEKRE -LLTGWMKANTTGGELIRAGVPADWVVADKTGGGYYGTRNDIAILWPPTGAPLVLAVMSSK -DAQDAEYSNALIARATTQA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. IEGM 248 TaxID=2704615 RepID=A0A6B2K7B6_9NOCA ----LDATIDALEAQYSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLGQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARVVGDESTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRSSKTSDKRMRAGLPTGWTAADKTGGGGFGTANDAGVAWSPDGAPLVLAILTDS -LTEGAQGNNQAIADTTAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5065 TaxID=1463855 RepID=UPI0004C221B1 ------ARLRELEERHAARLGVYAHDTATGRTV-RYRADERFPLCSVFKTLAVAAVLRDLD -RDGEFLGRNIRYTERDVTEHAPVTGEHLAAGMTAGALCSAAIRHSDNAAANLLLAELGGP -SAVTRFCRSIGDGTTRLDRREPELNSAEPWRTTDTTSPEAVGRSYARLLLGTALGRGDRA -LLTGWLLANTTGDEKLRAGLPADWAVAEKTGSGGYGTGHDVGVAWPPGRAPLVLAVLTSG -TEPDAVADSALIAGTATLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus subsp. albus TaxID=67257 RepID=A0A0X7JP80_9ACTN -----HPRLAALERKYDARLGVYALATGTGAAV-THRADERFAFCSTFKGLAAAAVLHRHP ---LSHVNTVVTYTEADLMQHSPVTRKHVATGMTIRQLCDAAIRFSDGTAGNLLLREIGGP -GELTAFTRGLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGTDYRKVVLGNVLAADKRA -FLRGLLERNTTGARRIRAAVPRGWTVADKTGTGDYGTLNDIAVVWPAKSPPLLISLMSSK -STKDAAYDQVLIADAAAYVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces yangpuensis TaxID=1648182 RepID=UPI000629CE8D ------RQLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKTPAAAAVLRDLD -RDGEFLARRIHYSQGDVTSGGLVTERNIAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALAPRHRE -LLTRWLVSSTTSVDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPLELAVLTTM -AEPAAPRRNALVAKAAAALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides saopaulense TaxID=1578165 RepID=UPI0008A99328 ------NEFAALEKNFGGRIGVYALDTGSGRTV-GHRADERFLMCSTVKTFIVSAILHRRR -SVPGLLDQRIQYTQADLLEWAPITSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KETEKFVRGLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPSGWTVGDKTGSGFKGESNDIAVIWPPGRAPIVVAVLTVP -EDPKSTQGKPTIAAATRIALQAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoluteus TaxID=29306 RepID=A0A4Z1D8W8_STRGP ----LRPGLAALEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPADILSNSEQSKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRE -QLVGWLRGNTTSGRRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTPLLLCVLSTK -PAPDAPVDEALIEETARLLA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Xanthomonas campestris pv. translucens TaxID=343 RepID=A0A5C1ZC92_XANCT --qTLAQRLAGIERRTRGRLGVTLLD-GSGTVLgGQRQDERFPMCSTFKFVLTAAVLQRVD -RGELSLQQRLQVRASDMLSHAPVTERHVGGTLSVAELCRATMLFSDNPAANLLFPLVGDP -PGLTRFLRTLCDAQTRSDRHEPEMNRFAAGDPRDTTTPAAMAATLRTLLLGDVLRPASRQ -CLSEWMIDNRTGDACLRAGLPRSWKIGDKTGSNGTDTRNDIAIVWPPGRTPLLLTAYLNG -AKVDEAARDAALKAVAVAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD79F85 -----EAQLAALEGKHPGRICVSILDMASGRRI-EHRAGERILMCSTFKVLAAGLVLARVD -KGKEKLDRRIRYTESDLIGGSPATKARVGDGMTVAELCAAAVTLSDNTAANLLLASFGGP -GAITAFCRSLGDETTHLDRIEPQLNYDTPEDLRDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITTKTGDARLRAGVAKDWLVGDKTGTSDAGNANDIAVLWPANRAPIIVTAYCEI -PEIAAGERNAIVAEIGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Variovorax soli TaxID=376815 RepID=UPI000A056F90 ---DVQARLADIEKRSGGRLGLHAIDTATGRAL-GWRSEERFAMASTFKMLLAAAVLHLHE -RTPAVLEQRLPVRQSDLIAHSPVTASHLANGITARQACEATVQVSDNAAANLLLPLVNGP -AGLTAFLRECGDAVTRLDRTEPTLNTNLPGDPRDTTTPAAMAQTMRRLLTGPVLAPASRE -QLIGWLVGATTGMARLRAGLPKDWRTGDKTGTGANGAANDVAITWPAGRAPIVMAVYLSG -SSRPSSVLDATHAQAAGVVAEAf ->[subseq from] Beta-lactamase n=1 Tax=Moraxella porci DSM 25326 TaxID=573983 RepID=A0A1T0CJX5_9GAMM ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDTAKQVFH-- ->[subseq from] UPI0012FE7EAE UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012FE7EAE --sKLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPHLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLIRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Streptoalloteichus hindustanus TaxID=2017 RepID=A0A1M5CII9_STRHI -----HDRLVELERQYEARLGVYAVHTGTCATV-AHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTLVKYTEADLMKSSRITRQHVDTGMTIRELCDAAIRFSDGTAGNLLLRDLGGP -NRLTAYVRGLGDRVTRMDRIEPFITEATPGDPRDTSSPRALGTTYRKIVVGNALPSEKRA -FIRDLMERNVTGGDRIRAGVEKGWVVADKTGTGDYGTLNDIGLVWPPNSAPLLISIMSSK -ATKDAEYKQALLADATRYAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces caniferus TaxID=285557 RepID=A0A640SIE2_9ACTN ------HALQKLERTHGARLGVHAVDTGTGRVV-AYRDGERFAHNSTFKALEAGAVLRKRS ---LSGMDKTIKYSKKDLVESSPVTEKHVASGMTLRALCDAAVRYSDNTAANLLFKELGGP -KKLNAVLKGLGDDVTHMERYETDLSTWDPGSTRDTTTPRAFAEDLRTFVLGDALGTAERA -QLTTWLRTNTTGDELIRAGVPKDWVVGDKTGMGSYGGRDDIAVIWRPHAAPLVVAIFSNR -TDEDADPDNKLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces somaliensis TaxID=78355 RepID=UPI001443A9A8 ------GRLRALERTHEARLGAFAHDTGTGRTV-AYRADERFPMASLFKTLAVAAVLRDLD -RDGEVLARRLHYTERYVREFSPVTGENLANGMTVAELCDATLTRSDNTAGNLLLRELGGP -AAVTRFCRSVGDGVTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYGRLLLGNVLAAHDRE -RLTRWMLANRTSDERFRKGLPADWLLADKTGGGGYGGNNDAGVAWPPGRPPVVLAVLTTR -FAPDAAADDALVAEAAGLLAE-- ->[subseq from] Beta-lactamase n=2 Tax=Clostridium botulinum TaxID=1491 RepID=A0A140AT92_CLOBO ----YNSAFSKIESDYGVKLGVYAFDTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSK -NDKDAKYDDKTISEASKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia gamkensis TaxID=352869 RepID=UPI0007A3A595 -----HDRLIELERKFDARLGVYARATGTGVTV-AHRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVVTYTRDDLLKNASVTPRYVDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP -AELTAYARSLGDPVTRMDRIEPAITEATPGDPRDTTSPRAFGEVYHRIVLGDALPADKRD -FLRDLLERNATGAQRIRAGTPQGWRVADKTGTGDYGILNDIAVVWPPDAAPLVVAIMSSK -ATRDAAYDQALLAEAAAYVMD-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A1L3NCN3_CLOBO ---QYNSAFSQLESDYDVKLGIYAFDTEMDKEV-VYHADDRFAYCSTFKALAAGAVLKQDS ---LDELKQVVKYKKEDVLSYAPIAKDNVDKGMTIEEICNAAVRFSDNTAANLLFDHIGGP -SGFKSALNQLGDNVTQPARIEPKLNEAIPGDIRDTSTPRQLVTDLQAYTTGNILTDDKKK -ILIDWMTGNATGNTLIRAGAPDNWVVADKSGTGPYGTRNDIAIVMPPNKKPIIIAILSTH -HTKEAKYDDKLIAQASKIVFDSf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000C6FDE9C ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGG- --------------TFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=UPI0003ACE39C -------RYAALEREHGARLGVFAVATGTGATV-AYRAGERFAFCSTFKTLAAAAVLHRHP ---LAHLEDRVTYTRADIDSISPITEDHVATGMTIRQLCDAAIRFSDGTAGNLLMRDIGGP -AGLTAYLRELGDGVSRMDDYEPELNRVRPGDPRDTTTPRAIAEDYRGLVLGTALPPDKRA -LIKDWLERSTTGAKRIRAGLPGGWKAAEKTGTGDYGRANDIAVVWPPGAAPLVVAVLSDR -PGRDARPDDALIAAATRRIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000506825D ------ADFEQLERAFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -PEKDAKIDNKLLADATAAAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter sp. Ag1 TaxID=1202448 RepID=J1GB62_9ENTR ----ITDTIQTTEDHIKGRVGFTEIDFLSGKVLgSHRHEERFPMMSTFKVLLCGAVLARVD -KGLEQLERRITYNEHDLDDYSPVTSLHLADGMSVSELCNAAITTSDNTAANLLLSTIGGP -EGLTQFVRSTGDNYTRLDRHEPSLNEALPGDERDTTTPAAMAQTLRKLLNGSLLKIASQQ -KLITWMQEDKVGGPLFRSVLPAGWMIADKTGAGEHGSRGIVALLGPRGKPSRIVILYITN -THSSMNELNEHIAGIGDSIIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DC4635 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRRLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas asiatica TaxID=2219225 RepID=UPI0010BFF684 ---TVAEAARALEAELGGRIGVVLRAPEDDPLA-VWRGDEAFPMASTFKVPLCGAVLARID -AGEEQAARILPVETAALVEWSPVTEQQAGRGMSIADLCHATITMSDNTAANLLLDTVGGP -AGLTAFLRDIGDATTRLDRTEPALNEALPEDMRDTTTPAAMADTLELLLFSELLSPEARA -QLESWMRQDAVADDLLRASLPEGWMIGDKTGAGGNGSRSIIAVLRGPAGEPWLATVYMTQ -TGGDMDKRNAAIARIGAAMI--- ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=A0A6A1R1U0_9BURK ---SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD -QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP -AALTAYARQLGDAVTRLDRNEPTLNRLSSDGLLDTTSPRAMAQTMHKLLVGEALSTASRQ -QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG -SSAEGAVKDACLADVAAWVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Nocardiopsis TaxID=2649073 RepID=UPI00135B5DAD -------DFERLEEEFDARLGVYAVDTGTGEEV-SHRPDERFAYASTHKALSAGAVLRRNS ---LEEMEEVVAYTEDDLVSHSPVTERHVETGMTLMEVADAAVRYSDNTAANLLMEELGGP -DGFEEALEAIGDDVTDPERMETELNEGVPGDTRDTSTPRAMATSLREFALGDVLPEDRRD -VFTTMLRGNTTGDTLVRAVVPEGWEVGDRTGAGGYGTRNVIAVVWPPEADPLVIAIMSSR -DREDAEYDDALVAGAAEVVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Kosakonia TaxID=1330547 RepID=A0A1V0LEB7_9ENTR ----LAEVVRLQEQQLGARIGVAVVDTTSGKTA-SYRGDERFPLNSTYKALLCGTLLSKVD -NGELALTDTTQFPRSALVAYSPVTEKFVAPAINWQQLCSAAVSYSDNTAANLLAQKLGGP -ASITRYLQTLGDSVTRLDRFEPELNSAIPGDLRDTTTPLAVSRTLQKLTLGTALKPGSRA -QLIQWMREDKVADTLLRSTLPAGWTIADKTGAGDFGSRSIISVVWPENNTPRIVVIYITN -TKATLKQSNAAIASLGKAIFS-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. BJA-103 TaxID=1911175 RepID=A0A2N8MSF5_9PSEU -----RADFEQLERAFTARLGVYAVDTATGREV-AFRSEERFAYASTHKVFTAGGVLQRTP ---LADLDRTVTYSQKDLVSNSPVTEKHVATGMPLRAVIDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPLLNDTAPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -VLVDIMRANTTGDTNIRAGVP-GWPVADKTGTAGYGTRNDIGVVWPPDRAPIVISVLTDR -ATADAKIDNKLLAEATAAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 295 TaxID=2606605 RepID=UPI0012DE82FD ----VDDQIAELERRHNARIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RGQQSLDHRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAANLLLKTIDGP -AGITAFARSVGDQRTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDAGIAYGPDGQRLLLVMMTRS -QA-DDPKAD-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea septica TaxID=472695 RepID=UPI000A11BEB0 --------AQQEEQALKARIGIAVIDTGAESVA-SYRGNERFPLNSTHKALLCGALLSAQD -KGKLRLTERTQFDRTALVTYSPVTEKFVAPAMSWQQLCSAAISYSDNAAANLIAKKLGGP -IAVTRFFADLGDKVTRLDRSEPELNSAIPGDVRDTTTPLAVSETLRQLTLGEALTPASRA -QLLQWMRDDKVADALLRSVLPTGWSIADKTGAGEYGSRSIISVVWPQNGKPLIIAIYITQ -TEATLVQSNAAIARIGKAIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudorivibacter rhizosphaerae TaxID=2570323 RepID=UPI001126FCCB ----ADKPLRSIEQAIGGRLGVFAFDTASGRSL-AWRADERFAMCSTFKLLLAAAVLHRVD -QGRATLDQRLRVTAADLVNHSPVTAPRVEQGITVTEACEATVTVSDNAAANLLLPLVAGP -KGLTGWLRGVGDKVTRLDRNEPALNSNIAGDPRDTSSPRAMASTTARLFAADPLTDASRE -QLRRWIEAASTGYRRLRAGLPADWRVGDKTGTGANGSVNDVAVAWPAGRQPLVLAVYLSG -SSRPMAELEAAHAEVARQVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1164966.3 TaxID=1856861 RepID=A0A1A0LYT3_9MYCO ---DLTGRFDELERKYGARLGVYVPAAGAVPEI-AHRADERFAFCSTFKAPLVAAVLQHNP ---LPHLDKVVTYTAEDIRSVSPVTQQHVQTGMTIRQLCDAAIRYSDGTAANLLLAELGGP -AAFTAYLRSLGDTVSRLDQEEPELNRDVPGDERDTTTPRAIALVFQKLVLGDALPSDKRA -LLTDWMARSTTGAKRIRAGFPADWKVIDKTGSGDYGRTNDVAVVWSSNGVPHVVAVMSDR -VSYEAPSNDAIVANAATIVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus pantothenticus TaxID=1473 RepID=UPI0009868B42 --------FLLLEKEYDAKLGIYAMDTGTGKTV-SYRAEDRFAYASTHKVLAVGVLLQKMN ---VNQLEETVLIKKEDLVNYNPITEKHVNKLMTWKELSDASMRYSDNTAANYILKRIGGP -AGFKQALRDIGDDVTKPERIEPALNKVKPGETRDTSTPKALARSLQAFTMGDVLTKQKQD -LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGGASYGTRNDIAIIWPPNEDPIILAVLSSR -DEEDAEGRDELIAKATEEVM--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB0856 TaxID=1637869 RepID=UPI00075B304C ---AAQAELTALEKASNGRLGVAALDTSSGARI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4SAJ3_9PROT ----LKAAVLAAERSTGGRIGLAVHDTATGRRF-SHRGGERFPMASTFKMVMVAAILEQVD -RGRDRLDRAIPVAARDILDVSPVSKQHVGGTATVAELAEATIIYSDNTAANLLLAAVGGP -AGLTAFLRRIGDPVTRLDRIEPLMSEALPGDPRDTTSPDAIVATWEHLLLGRILSPASRD -RLTAWLVANTTGGTRLRAGLPPGWKVGDKTGTGGHGSVNDIAIVWPDRAGPLFIASFANG -GTAASDKIYSAHAMLAAAIT--- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=UPI000DCE4C6D -----TDEINKLEKDFNGRIGVYALDTGSGKSF-SYRANERFPLCSSFKGFLAAAVLKSFQ -DNQLNIYQIVNYNTRNLEFHSPITTRYKENGMTLGDMAAAALQYSDNGATNIILERIGGP -EGMTKFMRSIGDDYFRLDRWELDLNTAIPGDERDTSTPAAVAKSLKNLALGNILNEDEKQ -TYQTWLKGNTTGAARIRASVPTDWEVGDKTGSCGYGTANDYAIVWPKNRAPLIISVYTTK -SEKEAKHDDKVIAEASRIAIR-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A426GTB3_9BACI ---NAMEKFEQLEKEYDARLGVYAIDTGTKETV-EFHENERFAYASTFKALAAAVLLKQNP ---ISVLEETRTFTNEDIVTYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFKELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGESRDTSTPKALATTLEVFGISEYLPADKQE -IFTNWLKGNTTGDSLIRAGVPESWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR -NEENASFNDKLIAKAAKVIVQAy ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sediminis TaxID=1397368 RepID=A0A4Q7V2S8_9PSEU ---SAQEQLASLEQRFGGRLGVSATDTGNGTVI-GHRADERFLMCSTSKFLAAAAILQMRT -TQPGLLDRRIRYDASQIVRNSPITSQHVADGLPVSELCRAAITVSDNTAMNLLLGVLGGP -PALTAYVRTIGDTVTRQDRTEPGLNTTSPGDERDTSTPARMASNIRALALGDALDPQGRD -VLYGWLNANTTGGTRIKAGLPAGWGVGDKTGSGDQGEVNDVAVVRPPGRAPLIMSVFAAP -ANPDAPSDAAVVAEAGRILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. UNPF46 TaxID=1141168 RepID=UPI00114DC425 -------ELESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDSTSRLDHNEPELNRSPPGNPQDTTTPVAMAGNLRRLVVGEALTPASRT -QLTEWMVNCKTGANRLRGGLPAGWIVGDKTGNNGKDASGDIAVVWPRDTTPILITAYTQG -GTPNPAQIEAAFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces cinnamoneus TaxID=53446 RepID=A0A2G1XJU6_STRCJ -----SRRLSSLEREHSARLGVFARNLKTGRTV-LHRADERFPMCSVFKTLAVAAVLRDLD -RDGEFLAKRVHYTEKETKDYAPRTGENLAHGMTVEELCGAAISFSDNAAANLLMRELGGP -TAVTRFCRSAGDTTTRLDRWEPALNTAEPWRTTDTTTPRAIGHTYARLVLGDVLAPRDRE -RLTGWLLANTTSAKRFRLGLPAEWTVADKTGGGDYGTNNDVGLAWTPDGTPIVLAVLTTK -HEPKPPADDPLVARAAELLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DF2817 ---DLADRFAELERRYDARLGVYVPATGTPAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora cheerisanensis TaxID=81942 RepID=UPI0009FBE1C3 ---AAAEAFRRLEERFGARLGVYVLDTGSGREV-AHRADERFAFASTSKALVGGALLRRAS ---DADLERVVTYRQQDVLAWAPVTSQHLATGMKLRDLLAASLDHSDNTAANLVMAEVGGP -AAVQQALRDLGDSTTDVSRTEPALNEAVPGDRRDTSTPRVLADDLRQYLLGDVLPPARRQ -LLTDLMLANTTGGPYIRAGVPAGWQVADRTGNGGYGTRNDLAVVWPGGGKPLVVAVLSDR -SRPDAPSNDTLLAEATEAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AG855 TaxID=2183898 RepID=A0A420D4P4_9RHIZ -----TAAARQVESRLGARLGLMVVDTETNRQW-QYRSGERFAMASTFKALACAALLD--- -AGTQLLSRDIKIEAKDLLAHAPVTSKRVGTRMTAGDLCAATLSTSDNTAANLVLSTLGGP -KRVNAFLRSIGDTVTRLDRMEPALNEATPGDPRDTTTPEAMARTIGELLIGDGLASSARR -QLTRWMEANAVADDLLRAGVPRDWRIADRTGAGGHGTRGIVAVMWPPGKKPVVAAIYLTE -TEASLATRDAAIAELGRVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=UPI000C6F149C --------FADLERRYDARLGLFAVNVHTGHVL-DHRADERFAMCSTFKTYAAAALLREHG -LDSGYFDKLIHYTEADLVAGSPITKPSAGTGMLVHELCAAAINRSDNTAANLLLAELGGP -AAIAPFARSIGDGSTRLDRWEPDLNTAIPGDERDTTTPGGIAAGHRALVVGDALGGPERD -RLTGWLFTNTTGGKRIRAGLPPTWRTGDKTGTGDYASANDVAVTWTDKGHPIVIAVLTTR -PRKDDEVNNGLHAETARIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas pictorum TaxID=86184 RepID=A0A0R0AR18_9GAMM ------RDFAALEAESGGRLGVCLWHPASGARY-GHRMQERFPMCSTFKFLLSAAVLYRAD -RGQLALDRRVPVRAADIIDHSPVSQRHVGKDLTVRDLCRATMITSDNAAANLLLPLVGEP -AGLTAFLRAQGDAVTVCARYEPEANRFAPGDPRDTTSPAAMAANLQRFVLGDVLAPASRQ -QLADWLIDNQTGDARLRAGLPRGWRVGDKTGSNGSDATNDIAVLWPEGGSPWLLASFLQG -SALDDDGRNGILRRVGELA---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_023 TaxID=2175657 RepID=UPI000D85BC5E ---AAERAFAALETEHHARLGVVAIDTGSGVGV-AHRADERFAFASAAKVFIAATVLDAAA ---PDDLDAVVPIGQGDVLSYAPVTGQHVGSGMTVRALLAAMVRSSDNTAANLLVARVGGP -AAVQRWLRGIGDDVTRVDRVEPDLNEAVPGDERDTTTPAQFAADLRTVLLG-ALDPDDRA -LLVGLMRGTTTGAGTIRAGVPEGWTVADKTGTGSYGVRNDVGIVTPPGRDPIVLVVMTGH -DTADAEPDDALVAAATRTAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00040BA8E6 --hALEARVAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGRP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGAMMETLRKLIFGEVLFRSSRA -QLAGWMVMNKTGDSRLRAGMPESWMIADKTGGNGHGNNNDIAVAWSPNRGAIVVATYCEI -PTISADERNAVVAEVGRLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 01325 TaxID=2203202 RepID=A0A429BLB8_9ACTN ---ATTDRLRDLERQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD -RDGEFLRRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR -LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK -PAQDAAWDDALVAETAALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756FE11 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. TSRI0078 TaxID=1718951 RepID=A0A1Q4WQ80_9ACTN -----DPEFERLEEEFDVRLGVHALDTGTDQVV-EFQADERFAYCSTFKALAFGAVLDRTP ---VDELDRVVTFSEEDLVFHSPVTREHVADGMTLREIGDAALRHSDNTASNLLIEELGGP -EGLEEALRGIGDDVTRVDRVAPEMAQAVPGDVRDTSTPRAMTASLRAFALDDVLPEDRRG -VLVDMMRANTTGDDLIRAGAPEGWTVGDKTGACGYGTRHDIGVLWPPEGDPVVLAVMSSR -DEAGAQYDDALIARATELAV--- ->[subseq from] Beta-lactamase protein TEM-1b n=469 Tax=cellular organisms TaxID=131567 RepID=A0A1Z1V1P1_ECOLX -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Putative Beta-lactamase n=1 Tax=Streptomyces aurantiacus JA 4570 TaxID=1286094 RepID=S3ZZU2_9ACTN ------PRLTALERKFDARLGLYALDTATGATL-AHRADERFAFCSAFKAIAAAAVLDGNP ---LSHLDDRVRYDKGDLMKHAPITSRHVGTGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP -NRLTAYARGLGDQVTRMDRFEPAITEATPGDPRDTSSPRAFGTTYREIVLGDALPKPQRA -FLRDLLERNATGAKRIRAGLPRGWTVADKTGTGDYGTLNDIAVVRPPKSPPLLVAIMSSK -ARRDAPYDEALLAEAAAYVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Agreia sp. Leaf335 TaxID=1736340 RepID=UPI0006F87911 -------AFAQLEQEFDARIGVYALDPQTRAEV-AYRADERFAYASTFKALAAGILLKTVP ---DDELDEIVSYDSSELLPNSPVTEENVADGMTLRAVAEAAVRFSDNTAGNIMLERLGGP -EGFTQALRELGDTTTSSDRVETELNSAIPGDLRDTTTPRAFALDLATLLTTDALGAAQQA -QLIDWMTGNATGAELITAGLDAGWAVADKSGAGAYGTRNDIAVLWPPSGSPIVLVVMSNR -PTEDADYDNALISRAAEATL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106PWF4_9BURK ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiales bacterium TaxID=1891238 RepID=A0A2W4UAM5_9BURK ---SLQTQLQQLEATAQGRLGVHIIDTATGLSH-GHRMDERFMMLSSFKLVASAFVLARVD -RGQESLERRITFAKTDLVTYSPVTERFAGTAMSLGGLCEATLTTSDNSAANFILDSFGGP -VALTRFARELGDDTTRLDRRETELNTGTAAALLDTTTPRAMALTLQKLLLGNALSPASRQ -QLQRWLVANTTGDKRLRAGLPKGWRVGEKTGTNAT-DANDIGIVWPANGAPLIITAYLAE -STASSAVKEAALAGVARLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Agreia sp. Leaf210 TaxID=1735682 RepID=A0A0Q4F185_9MICO -------AFAQLEQEFDARIGVYALDPQTRAEV-AYRADERFAYASTFKALAAGILLKTVP ---DDELDEIVSYDSSELLPNSPVTEENVADGMTLRAVAEAAVRFSDNTAGNIMLERLGGP -EGFTQALRELGDTTTSSDRVETELNSAIPGDLRDTTTPRAFALDLATLLTTDALGAAQQA -QLIDWMTGNATGAELITAGLDAGWAVADKSGAGAYGTRNDIAVLWPPSGSPIVLVVMSNR -PTEDADYDNALISRAAEATL--- ->[subseq from] Beta-lactamase n=1 Tax=Salinisphaera hydrothermalis (strain C41B8) TaxID=1304275 RepID=A0A084IPD5_SALHC -----VAGIAHIESQYGGRLGVAVLDSATGRIA-SYRGDERFPMCSTFKIFAAAAMLANVD -AGSERLNRRITYEPKDLVIYSPITRGHLTDGMTLGALARAAVRWSDNSAANLVLDSFGGP -DALNTYLRGLGDRVTRLDSREPICSQIVAGSVANTSTPVAMVGTMRSILLGDALTASSRR -RLTGWMIDGRTGDKRLRAGLPASWRVGDKTGSGDLATANDVAIAWPPHGPPLLIAVFFTG -AP-GAVDRDRPIADVGRLIG--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1164966.3 TaxID=1856861 RepID=UPI0009EDB326 ---DLTGRFDELERKYGARLGVYVPAAGAVPEI-AHRADERFAFCSTFKAPLVAAVLQHNP ---LPHLDKVVTYTAEDIRSVSPVTQQHVQTGMTIRQLCDAAIRYSDGTAANLLLAELGGP -AAFTAYLRSLGDTVSRLDQEEPELNRDVPGDERDTTTPRAIALVFQKLVLGDALPSDKRA -LLTDWMARSTTGAKRIRAGFPADWKVIDKTGSGDYGRTNDVAVVWSSNGVPHVVAVMSDR -VSYEAPSNDAIVANAATIVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK022 TaxID=2512123 RepID=A0A4Q7Z736_9ACTN -------ELAALEKRYGARLGVYARNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPADILSNSEQTRAHQQTGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALGGSERE -QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYASANDLGVAWTGKGTPLLLSVLSTR -PEPDAPVDEALIEETARLLA--- ->[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI0007E195DB ----YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDILSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVAIPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFIAILSSK -NDKDAKYDDKTISEASKIVFDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Saccharothrix syringae TaxID=103733 RepID=A0A5Q0GYV6_9PSEU -----DDEFARLEAEFGATLGVHAVDTGTGREL-SYRADHRFAHASTVKALAAGAVLLRNS ---LPELEEVVTYTRADLIAHSPVTEGRVDTGVTLREAVDAAVRFSDNTAGNLLFRELGGP -AGLAAALREVGDTTTRVDRVEPDLNEAAPGDLRDTSTPRAVTGSLRAFALGDALPGEERA -VLVDLLRRNTTGDRLIRAGAPAGWVVGDKTGTGGYGTRNDIAVAWPPDGAPVVLAVMSRR -ATEGAAHDDALIARAATVVFG-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A649UHM4_SERMA --------IKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVLLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTTQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNGK----------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A4R7QMU9_RHOOP ----LDATIDALEAQHSTRIGVTAANPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTGAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759D36A ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1S7D5Z3_9BACT ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALL---------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces phaeochromogenes TaxID=1923 RepID=UPI0006E2B1C7 ---SLAGQLADLEREYAARLGIFAHDTATGRTV-AYRADERFPMCSVFKTLTAAAVLRDLD -RDGEFLARRIRYTKEYVTAYAPITDENVAKGLTVEELCSAAVSQSDNGAANLLLRELGGP -TAITRFARSTGDRITRLDRWEPELNSAEPWRKSDTTSPRAIGQTSARLVIGRALPAEDRE -RLTGWLIANTTNTERFRAGLPSDWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK -YAADGPQENPLVARAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-6131 TaxID=1463874 RepID=UPI0004C24AA1 --sELTNKLRALEHAHGARLGVFACDTATDGTV-TYRADELFPICSTFKTIAVAAVLRDLD -RDGAFLAKRLHYTATDVAEYAPITGLNLEAGMTVEELSAAAIRYSDNAAANLLLHELGGP -GTVTRFCRSIGDRVTRLDRWEPALNSAEPGRDTDTSSPRAIGQTYARLTIGKALDAPDRR -RLTGWLQSNTTGANRLRAGLPTDWTVAEKTGTGGYGTTNDVGIAWPVGGGSITVAVLSTK -SDPSAPADEPLIAGTARLIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4V4P2S2_STEMA -----ATDFATLEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSVLAATVLSQAE -RTPALLDTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATLITSDNTAANLLFGVVGGP -PAVTAFLRASGDALSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPGSRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRATVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. SAU14A_NAIMI4_5 TaxID=2072413 RepID=A0A3Q8FUG3_9GAMM -----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -SALTAFLRAQGDTVTRNDRYEPDMNRFAKDDPRDTTSPAAMATSLARFAVGDGLSEKSRL -QLADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alba TaxID=53437 RepID=UPI001367D4F3 ---DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS ---LEEMERVITYDEDVLVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP -EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE -VLVDMLVRNTTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM -EVEDAEPQDSLIAEATEVVVE-- ->[subseq from] Beta-lactamase AER-1 n=2 Tax=Bacteria TaxID=2 RepID=BLA1_AERHY ---KLIQAVQSEESALHARVGMTVFDSNTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD -GKSLSLGQSVSISKEMLVTYSPITEKSLSPEVTFGKICQAAVSYSDNTAANVVFDAIGGA -TGFNAYMRSIGDEETQLDRKEPELNEGTPGDVRDTTTPNAMVNSLRKILLGDALSASSRS -QLTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ -TKASMQASNQAIARIGVV----- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis dassonvillei TaxID=2014 RepID=A0A223QDZ3_NOCDA -----ADEFADLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYCSTHKAFSAALVLQRNT ---PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLVEVADAAVRYSDNTAANLLFDELGGP -DGFEEAMEGMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVLWPPEGDPIVLAVMSSR -DEEDAEYDNALIAGAAEVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=A0A244E0T1_9BURK -----RGRFEKLEASSGGRLGVAALNTADGSYV-SYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELCAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VTKQTLPRDEVVAEAARIVFD-- ->[subseq from] Beta-lactamase L2 n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A655MB08_STEMA ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIEDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQREAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A0M7D2U3_9BURK ---TFQQALAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQEYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYEPELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMSADWRIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium phyllostachyos TaxID=582672 RepID=A0A1H0AKK0_9RHIZ -----EPELEAIERRIGGRVGVAAGS-AERILV-GYRADERFPMCSTFKVLAVAATLARVE -TGSESLDRTLSYHPGDLLSYAPVTRKALEAQMSVGDLCAAAIVWSDNTAVNLLLTRLDGP -EGLTEWLRGTGDPVTRLDRDEPTLNSAIPGDPRDTTTPEAMRASLGRILLGTVLSPASRD -RLEGWMVGSQTGLKRLRAGLPKDWTMGDKTGTGTNGSINDVAILRPPGHAPVTAAVYITG -STAPMATVEAAHAEIGRLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Labedella populi TaxID=2498850 RepID=A0A3S4A357_9MICO -----DPAFTALEEEFDARLGVYALDTATGAEV-QWRAGERFAFASTYKALAAGALLDTVG ---IPGLLEVVTFTEDDLVAHSPITEEHVDEGMTLSDVADAAIRYSDNTAGNLLLEALGGP -EGFDSALEEIGDDVTVSEREEPDLNSAIPGDVRDTSTPAALAADLRAYVLGDALSEDESA -LLTDWLRLNTTGDDLIRAGVPGDWTVADKTGSASYGTRNDIAVIWPADGDPLVLAILSDR -AAEDAESDDALIARATEIAVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID6139 TaxID=2690320 RepID=A0A6B1K111_9ACTN ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE -RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. endophyte_N2 TaxID=2153485 RepID=UPI000FFE7B5F ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE -RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001376F02D ---QLQNLCQKLESTAQGRLGVCILDTQTDQQW-GWREDELFMMLSSFKLLASALVLHRVD -QGKENLQRRVTYSRNSLVPWSPITEKYADGLMTLGELCAATITTSDNTAANLILDSYGGP -NALTAYARSLGDTVTRLDRNEPSLNRQSIDGLLDTTSPRAMTKTMNKLLMGNALESSSRQ -QLREWLIANTTGGKRLKAGVPNSWLVGDKTGTNAT-DANDIGILIPPQGAPLLISVYLAE -STADNSIKDACIAEVAKWA---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia yamanashiensis TaxID=209247 RepID=UPI000AA56371 -----ETTLRGLEEKYGARLGVYAVDTKSGREV-AYRSGERFAMASTFKGLACGALLKDYP -LSSGYFDQVIRFGADEVVANSPVAEQRVETGMTVAELCQAAITVSDNTAGNLILRLQGGP -GEFTAFLRSLDDSVSRLDRWETELNTDTPGDERDTTSPAAVAADYEKLVLGNALGEPERE -MLKGWLLANTTGGQRIRAGLPQGWTVGDKTGTTERGGANDVAVTWTDKGVPVVIALLSSK -TGADTKADNALLADATRAVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0004A7804E -----HDRLFELERKFDARLGVYALDTASGATI-AHRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVIRYTEEDLTKNAAITPRHVATGMTIRDLCDAAVRYSDGTAGNLLLRDIGGP -AELTAYLRGLGDPVTRMDRIEPAITEATPGDPRDTSSPRALGTDYQRIVLGDALPEDKRA -FLRDLLERNATGAVRVRAGVPQGWKVADKTGTGEYGTLNDIAIAWPPDRAPLVLSLMSSK -ATADAEYDQALLAEAAAYVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=A0A2I8XJQ1_9VIBR ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMLNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGYGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NL15-2K TaxID=376149 RepID=A0A401MT92_9ACTN ------AELKGLERKFDARLGVYAIDTGTGREV-AYRDGERFGYHSTFKAMAAAAVLRKYS ---LSGMNEVIKYSADDLLPNSPITEQHVETGMTLRELCDAAVRYSDNTAANLLFEALGGP -KGLEAELRKLGDDVTVMERIETGLSDWVPGETRDSTTPRAFAEDLRAYVLSDVLRKPERA -QLTKWLKTNKTGDELIRAGVPKGWVVGDKTGSGGYGGRNDIAVVWRPHADPVVMAIMSNR -SEKEDTYDNKLIAEAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Erwinia sp. 9145 TaxID=1500895 RepID=UPI00054E74D8 -------KAQAIEKRLNARVGVAVIDTGSDRRW-LYNAEQRFPLNSTFKAFACGALLYQAD -AGKNDLNKTTRVTREEMIPYAPVTETLIGQSVSLDRLCAATMRTSDNVAANKIVTSIGGP -EGMTRFMREIGDSVTRLDRREPDLNEATPGDLRDTTTPAAAVASLRKLVLGNALSGASRE -KLTRWMIEDAVGGPLLRAGIPSTWRIADRTGAGGHGSRSVIAVMWPPSHAPVVVAVFITE -TTATLAARNAAIAELGAALAH-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001124196E ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAIIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0013C8788F ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGXPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus melanogenes TaxID=411235 RepID=UPI000A022A1A -----DGRLRALEQEHSARVGVFAYDSGTGRSV-TYRAGELFPMCSTWKTLGVAAVLRDLD -RDGEFLAKVIHYTRQDVTAYAPITGRNVADGMTVGDLCAAALEYSDNGAANLLLRQLGGP -QAVTRFCRSVGDRITRLDRWEPELNSAEPGRVTDTSTPRALGLTCARLTLGGALDATDRK -RLTGWLLANTTGAHRLRAGLPADWVVADKTGTGEYGTANDVGIVRPPGRGPIVMAVLSTK -HDSAAAADEPLVAGVAALLAAAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=UPI000A854662 ----LNGPLSALQARAGGKLGVFAQNTGSGDFI-SFNAESRFAMCSTFKVLLAAAVLARVD -NGELSLDQTVAFSRRDLVPHAPVTSLRVAEGMSVRDLLAATLEVSDNPAANLLLPLVGGP -SGVTDFVRETGDLTTRLDRTEPELNSNLPGDLRDTTTPLAMGRTLRTLLLGRRLSVASKA -HLSAWMVASTTGKRRLRAGLPDTWRVGDKTGSGANGAFNDVAIAWPTVGAPLILAVYLSG -SGTPTDTLDAVHAVAARLVS--- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A2S5VPG8_9MICO -------AFAQLEQEFDARIGVYALDPQTRAEV-AYRADERFAYASTFKALAAGILLKTVP ---DDELDEIVSYDSSELLPNSPVTEENVADGMTLRAVAEAAVRFSDNTAGNIMLERLGGP -EGFTQALRELGDTTTSSDRVETDLNSAIPGDLRDTTTPRAFALDLATLLTTDALGAAQQA -QLIDWMTGNATGAELITAGLDAGWAVADKSGAGAYGTRNDIAVLWPPSGSPIVLVVMSNR -PTEDADYDNALISRAAEATL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces kanasensis TaxID=936756 RepID=A0A100Y9P7_9ACTN ----ADRAFRDLQRRFDARLGVHAVDTGTGREV-AFRADDRFAYASTFKALAVGVLLRER- --GLDGLDEVIRYSRDDLVGHSPVTEGATGTGMSLRDLCAAALRYSDNTAANLLFDALGGP -DGLERKLEALGDDVIEMDRRETDLSEGRPGDVRDTSTPRAMARDLRAFLLGDALEPAERA -QLRTWMATNTTGATLVRAGVPAGWAVADKSGTAGYGGRNDIAVVWPAGGAPLVIAVMSSR -DRKGAERRDELVAQAAAAAVR-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. KC345 TaxID=2530371 RepID=A0A4R4QZ11_9ACTN ---AVGKQLRALEKTRQVRIGAYAIDTASNRGV-GYRADERFPFLSTFKAVVCGAVLQKAR -RDPGLMDRVIRYKESDLVDHSPVTEKHVKTGMTVAELCRAAITVSDNTAANLVLKQIGGP -AGDTAFFRSLGDRRSRHDRWETALNDWKPGERRDTLVPRDWARGLRTLTTGTALAPADRT -RLIGWMKASETGADRIRAGLPEGWTAGNKTGTGGYGTANDIAVAWPPGGAPLIIVVTTNR -RAADGTEDPAAIAKAASVLVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. A14 TaxID=1194106 RepID=UPI00141F393B ----LDATIDALEAQHSTRIGVTAANPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASRD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Mycetocola lacteus TaxID=76637 RepID=A0A3L7AI48_9MICO -----DAAFAALEAEYGARLGLFLIDTGSQRTV-EYRPDERFAFASTIKAHQAAAILQTRD ---IAALEEHVTFTADQIVSYSPITEQHIEDGMLLHEVVTAALQYSDNTAANLMFDRLGGP -SGLQQLLREIGDATINVNRIEPDLNEATPGDPRDTTTPRAHAHTLATFGVSNHLPIEKRN -LLTTWMKANTTGGELIRAGVPADWVVADKTGGGYYGTRNDIGILWPPTGAPLVLAVMSSK -DAQDAEYSNALIARATTQAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=A0A1D8BU79_9PSEU -----HDRLLELEREFDARLGVYAIAVGTGNTV-SHRADERFAFCSAFKGLAAAAVLHRHP ---MSYLDTVVTYTEADLMASSAITEQHVATGMTIGALCDAAVRFSDGTAGNLLLRDIGGP -AELTAYTRSLGDTVTRMDRYEPTIVEATPGDPRDTTSPRAIGTDYHDIVLGAALPAEKRD -FLRDLLERNATGEQRIRAGLPAGWTVADKTGTGDYGTANDIGIVWPPDAEPIAIAIMSSK -DERDARYDNALLAAATEYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora catharanthi TaxID=1712871 RepID=A0A5N6BCA1_9ACTN ---DVAAALRALETSFKGRIGAYAIDTATGKTI-GYRAGERFALASTFKAVAAGAVLARTT --DRELTRKVVHWTAGEVKPNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -QGLTRYFRTLKDPVSRLDRWETELNDWSPKEKRDTTTPAAVARDLRALTTGDALGAKDRS -RLIGWLRDNTTGDARIRAGLPTTWIVGDKTGTGGYGTANDIAVVWPADAAPIVMAIYTNR -RAADGATDDKVIAQTATVLA--- ->[subseq from] Beta-lactamase n=2 Tax=Nitrosomonas eutropha TaxID=916 RepID=Q0AH67_NITEC -------SIADIEAKVGGRVGVFAVDTGSGKVL-AHRPDERFAMCSTFKWVLAATILAQVE -QNLLSLSSHVLYGQADLLAYAPVTSMHAKEGMTVSELTRAAIVVSDNTAANLLLSKLGGP -SVVTEFVRSCGDAVTRLDRNEPTLNDNDAGDLRDTTSPRAMATLMGNVLCGNRLSSTSRD -LLLQWLRDCETGYDRLRAKLPKDWLVGDKTGTGEHGAVNDVAIAIPPGRSPILIAAFLSE -GRADRPALVAAHASISHLVAHHf ->[subseq from] Beta-lactamase n=1 Tax=Tistlia consotensis USBA 355 TaxID=560819 RepID=A0A1Y6CM52_9PROT -----AGSLTGLEQQVRGRIGVAALNVETGRRL-DNRSDERFPLCSTFKFLAAACVLRRTD -QGVERLDRRIAFTEGQVVALSPVTERRTGGAMTLRDLCEAAITASDNTAGNLLLDSFGGP -PALTDFCRSIGDSATRLDRKEPELNDVAADDPRDSTTPAAMLEDLRKILLGDVLSKLSRD -RLAAWLVASHTGRARLRAGLPGHWRVGDKTGTGLKGASADIAVAWPPGGGPILIAAYLTG -ALVPDGMRDAIYSQIGRMAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MUSC 1 TaxID=1678012 RepID=A0A1S2QFD7_9ACTN -----EAELRALEQWHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --DCAPPDKVIHYPPHDILPNSPRTAEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFFRSLGDEVSRLDRWETDLNGAVPGDLRDTTTAEALGGSFARLTLGRALSGADRS -RLVGWLKGNTTSGTRFGAGLPRDWVLADKTGTGDYGTANDVGVAWTTRGTPLLLTVLSAR -TARDAPADDALVAEAARVLA--- ->[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-48 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00047175B6 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKTTRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Hyphomonadaceae bacterium BRH_c29 TaxID=1629720 RepID=A0A0F2QPS8_9RHOB ------DSLEALERRSGGRLGVFMTDTGSGRSF-GHRADERFSMCSTFKMPLAAVILREAD -AGRLDLATAVPFTRADIVAYSPVTEPALAQGMTIAALAEAAQVQGDNTAANLLLSRIGGP -EGFTAILRSLDDTQTRLDRFETELNLGPPGELRDTTTPAAMAGLMTTLLTGDALSEPSRQ -RMIEWMVATSTGQARIRAGLPAGWRAGDKTGSGISNKYNDIAIVWPPGGAPLIVTAYYEG -PGDLRDEDQAVLAEVGRIAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. S4605 TaxID=1420897 RepID=A0A317KS62_9ACTN -----HHRLTELERRYDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAVLHGNP ---LSHLDTVVRYTERDLMKSSAITRRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -ARLTAYLRGLGDPVTRMDRFEPDIVTAIPGDPRDTTSPRAIGVDYQQIVLGDALPPDKRA -FLRGLLERNATGARRVRAGVPKDWTVADKTGTGDYGTLNDIALVWPPGSAPLVISIMSSK -ATRDAEYDQALIADAAAYVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas naasensis TaxID=1344951 RepID=A0A4S1WB23_9SPHN ---DFRNAILAVERASGGKLGLAVIDTGSGERF-GLHADQRFPMCSTFKLALGAAILKQVE -AKRETLARRIPVAAADIVSNSPFSEKRAGGSASVGELCHATITVSDNTAANLLLRTIGGP -AGFTRRLRAFGDPVTRLDRWETAMGEGAPGDMRDTTTPDAMADLARRLVLGGALAPTSRA -QLIAWLKATRTGLNGIRAALPEGWQAGDKTGTGGHGTDNQVAVLWRPRGAPLVVASYFTG -STLPQGQTRPLHAQVGRAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51163_SCH5372311 TaxID=1834097 RepID=A0A1A2CUC1_9MYCO ---DLTGRFDQLERKYGGRLGVYVPADGAVAEI-AHRADERFAFCSTFKAPLVAAVLQHNP ---LPHLDKVVTYTRDDIRSVSPVTQQHVQTGMTVRQLCDAAIRYSDGTAANLLLAELGGP -AAFTAYLRGLGDNVSRLDQEEPELNRDAPDDERDTTTPRAIAMVFQKLVLGDALPSDKRA -LLTDWMARSTTGAKRIRAGFPADWKVIDKTGSGDYGRTNDVAVVWSPGGVPHVVAVMSDR -ISYEAPSNDAFVANAATIVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=UPI0006CE48A7 ----ARKELRTLEASFKGRIGAYAVDTATGKTI-TYRSGERFPLLSTFKAIAAAAVLHKAR -TDPGLLNKVVHWTTAELQEHSPVTGKHVKDGMTVARLCEAAITRSDNTAANMLLKQIGGP -AGLTAYFHTLKDPVSRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALDARDRE -RLNAWLTANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDIAVVWPGKSAPIIMSIYTNR -GAADAAVDDKVIADTAAILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756FD08 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLDAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. YR290 TaxID=1882799 RepID=A0A2C8ZK56_9BURK ----ARERFEKLEASSGGRLGVAALNTADGSYV-SYRESERFPMCSTFKLLVVALVLKRSM -AEHSLLDERVRYGDADLVANSPVTKRRAGEGMTIGELCAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VTKQTLPRDEVVAEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E8DB94 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPRDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084B419D ---KLNEDISLIEKQVSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATATIDERNIVVWSPVMDKRAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Salinisphaera hydrothermalis TaxID=563188 RepID=UPI000A013167 -----VAGIAHIESQYGGRLGVAVLDSATGRIA-SYRGDERFPMCSTFKIFAAAAMLANVD -AGSERLNRRITYEPKDLVIYSPITRGHLTDGMTLGALARAAVRWSDNSAANLVLDSFGGP -DALNTYLRGLGDRVTRLDSREPICSQIVAGSVANTSTPVAMVGTMRSILLGDALTASSRR -RLTGWMIDGRTGDKRLRAGLPASWRVGDKTGSGDLATANDVAIAWPPHGPPLLIAVFFTG -AP-GAVDRDRPIADVGRLIG--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0006A59B44 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACAAMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_007 TaxID=2175648 RepID=A0A2W1VBZ2_9MICO ---SVDAAFRQLERQHDARLGVMALDTGSGQRV-AYRSGERFAFASTNKVFIVAAVLAGSS ---DADLDTVVHYDRGDLLSYAPVTSRFVDSGMTVRELVDATLRFSDNTAANLLVERVGGP -DAVERYLRGIGDHTTNVDRLEPELNEATPGDPRDTTTPAQFVTDLRKVLLGTTLDTTDRT -FLRDTMLDNTTGAATVRAGVDPTWPVADKTGTGEYGVRNDIAVVYPAGRAPVVVVVMTSR -DQPDATTDDALVAAATKAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobacter sp. Root1221 TaxID=1736433 RepID=A0A0Q6XVT3_9BURK ----LNGPLSALQARAGGKLGVFAQNTGSGDFI-SFNAESRFAMCSTFKVLLAAAVLARVD -NGELSLDQTVAFSRRDLVPHAPVTSLRVAEGMSVRDLLAATLEVSDNPAANLLLPLVGGP -SGVTDFVRETGDLTTRLDRTEPELNSNLPGDLRDTTTPLAMGRTLRTLLLGRRLSVASKA -HLSAWMVASTTGKRRLRAGLPDTWRVGDKTGSGANGAFNDVAIAWPTVGAPLILAVYLSG -SGTPTDTLDAVHAVAARLVS--- ->[subseq from] UPI001444C5D2 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001444C5D2 ------VRLMALERKFGARLGLYALDTGTGATI-AHRPDERFAFCSAFKALAAAAVLDRNP ---LSHLDTLVRYTEDDLMKHAPVTARHLDSGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AELTAYARGLGDRVTRMDRTEPAITEATPGDPRDTSSPRAFGTSYRKILLGGALPTAKRA -FLRDLLERNTTGARRIRAGVPRGWTVADKTGTGDYGTLNDIAVLYPPKSAPLLLALMSSK -PAEDAAHQEELLAEATAYAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces angustmyceticus TaxID=285578 RepID=UPI000A3656F9 ---ALVGQLRDLEQEYSARLGVFAYDTATGRTV-DYRADERFAMCSVFKGLAAAAVLRDLD -HHGEFLARRIRYTEKYVTDYAPVTGKNVAQGMTVEDLCAAAVSQSDNGAGNLLLRELGGP -TAITRFCRSIGDGTTRLDRWEPELNTAEPWRTTDLTTPRAIGRTYARLVVGDALPAEDRS -RLTGWLVANTTNGERFRAGLPADWRLADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK -YDPKGPTDNPLVARTAALV---- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Streptomyces philanthi TaxID=371608 RepID=A0A367F340_9ACTN ---RVTKALAALEKRHDRRLGLYMRDTGSGRTV-AYHADERFGFCSTAKVLQAAALLEHAD ---DAELNRVITYERDDLQDYAPITRKHPDTGMSVRALLKAALQYSDNTAANLLFEQLGGP -AGLQRKMRGLGDRTSVFDRIEPDLNDTPPGTTRDTSTPRALGQDLRRFLLDDALAPDRRE -LLATWMRGNTTGDDLIRAGVPSDWKVADKTGSGTHGTQNDIAVAWRPHGAPVIIALMSRG -DDEDSASDKALLAEATKAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007BA5D09 ---AAQAELAALEKASDGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVTGSPVTESHVDTGMTISQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARSATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Stackebrandtia albiflava TaxID=406432 RepID=A0A562V3Q2_9ACTN -----EDRFEALEDSYDARLGVYARDTGTDEEV-TFRADERFGYASTFKALAAGAILAEYG ---VDGLDRRIRYTADDLVPHSPETGKHVDDGMTLEAICEAAVRLSDNTAANLMFDALGGP -DGLQEVLVGLGDEVTEMDRYETALNDVGPGETRDTTSPRAFATDLAAFLLGDVLHAAERE -LLTEWMTGNATGAHLVSAGVPDGWRVADKSGAGGYGGRNDIAVVWPEDGAPIVMAIMSVR -ADPDAEPSDALIADATRIATD-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylotetracoccus oryzae TaxID=1919059 RepID=UPI001117BFF6 --------LVAIEARVGGRVGVFALDTGTGRSL-ANRPDERFALCSTFKWVLAAAILAQTD -RGRMSLGARIAYGPDDLIDHAPITKANIAKGMTLDALAAAAVTDSDNTAANLLLAKLGGP -TALTAFVRSVGDPVTRLDRNEPALNSNEAGDARDTTSPRAMVGLVNTLLCGQTLAPNSRD -LLLGWLRACKTGGDRLRAGLPRDWVVGDKTGSGRRGAINDVAIAFPPHRAPILIAAYLSG -SPARLPALAAAHADIGRWVAH-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. NAZ190054 TaxID=1747766 RepID=A0A132SCJ5_9MYCO ------ERLDELARRHNAEIGVYAVDLATQKSV-TFRDDQPFAMCSTFKAYAAAAVLQRTQ -TGELTLQDTVPIEAGDIRPHSPVTEPRVGTSMTLAELCQAALQQSDNAAANGLLRVLGGP -QAITAFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALGEGYRRILTGEVLNPTARQ -QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPSGEQVVLALMTKS -ASPDAPSLRPLIGELAALVLS-- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonas sp. 60 TaxID=2586975 RepID=UPI001423D092 ------RDFAALEKASGGRLGVTLLDARTGKRA-GHRQDERFPMCSTIKWMLAAAALHRAE -RQPGFLDERLPMRAEDLIDHAPTTRRHVGKDLTVRDLCRTTMVTSDNPAANLLLRHLGGP -PAITAFMRSHGDAVTRSDRYEPELNRFEPGDPRDTTSPSASAASLQRFVLGDALKPASRQ -QLADWLIDNETGDTTLRAGLGERWRVGDKTGSNGRDTRNDIGVLWPVGGTAWVLTAYLQG -ASVNSEQRDAVLARVAAL----- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus clausii (strain KSM-K16) TaxID=66692 RepID=Q5WLE8_BACSK ------DVFKQLEKEYDARLGIFALDTGTGETV-SYRADARFTYASAHKPLAVAVLLQQKS ---IDELEQLITYSADDLVNYNPITENHVESGMTLRELSDASIRYSDNTAANLIFHEIGGP -EGFKEGLRAIGDTVTEPERIEPELNSVEPGEIQDTSTPEALAKSLQEFALGESLPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILWPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVINLf ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. SCN 68-21 TaxID=1660154 RepID=A0A1E4EPC3_9RHOB ---TIAQAARAIETELGGRVGVALRRQGDAQVT-GHRPDERFPLSSTFKAPLCGAILTLVD -AGADQLDRPIGYTSADLVDYSPVTSTHN--AMTVGALCEATITLSDNTAANLLLDRLGGP -EDFTAYLRAIGDDTTRLDRRETALNEAAPGDPRDGSTPAAMTATLDRLLFGPILSAASRD -QLEAWMRADQVADDLLRASLPQGWIIGDKTGAGGFGSRSIVAVIRPPQGGPWLAAVYLTG -NKADMPTRNRAIARIGAAIVS-- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium diazoefficiens TaxID=1355477 RepID=Q89VV4_BRADU -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGQEQLAAVIPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNRSPPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GSPTAPQIEAVFARIGRMVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000841A1FA ---AAQAELAALEKASSGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMADMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Uliginosibacterium gangwonense TaxID=392736 RepID=UPI0003A1CDC2 --qASQTKLAALEGETGGRLGIACIDTATGKAF-GYRADERFPMCSTFKWLAGAALLKQVD -EKTKRLDQRIRFSHKQLLGGSPVTQKFADTEMSLAALCEAAIADSDNTAANLIVETLGGI -PAWNAYVRTLGDQLTHLDHPEPFLNKTQMGDKRNTTTPSAMCANLKHVLLEDALSPSSRE -QLKQWMLATRTGKQRLRKDLNSGWTLANKTGTGDTGTANDIGIYWPPTGQPIVLTVYLTH -AHVPLAQQEAAIAQVGHWVRDGw ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092B3368 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEEQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E3CD6 ---KLNEDISLIEKQVSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATSTIDERNIVVWSPVMDKRAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRFEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSNSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSFQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D3F9F ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACAAMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007557ECE ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHRARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVVGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium basiliense TaxID=2094119 RepID=A0A3S4BGG7_9MYCO ---DFRSRFAELERQHEARLGVFVPATSTTTEI-AHRAEERFAFCSTFKGLLVAAVLHQYP ---IDHLDSMVTYSSADIRSTSPITEQHLQTGMSIRGLCDAAIRYSDGTAANLLLDQIGGA -SAFTGYLRGLGDSVSQLDQEEPELNRDPPGDERDTTTPRAIALDYQNLVLGDALPADKRA -MLTDWMARSTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPSGAPYVVAIMTDR -ASYDAQPSDSLIADAARCVAE-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000A3628CF ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMENNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAVIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428XVJ5_9PSEU ------AEFEQLERAFAARLGVYAVDTANGREV-AFRADERFAYASTHKVFSAGGVLQRTS ---IADLDRTVTYGQKDVVVNSPVTEKHVGTGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPELNDTAPGDPRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTASYGTRNDIGVVWPPNRAPIVISILTDR -SAKNAKIDNKLLAQATAAVVK-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8HJ38_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLVD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A0D0J707_VIBHA ---KLNEDISAIEQHIAGRIGVAIWDTQSNEHW-DYRGDERFPMMSTFKTLACATMLNQMD -TGKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTLFLRSLGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDPLIRSVLPKGWSIADRSGAGGFGSRGVTAMIWKENHKPIYVSIYITE -TDLSLQARNQVIAQISQLIVDQy ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0005EF5489 ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLRTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A1B1K784_RHOOP ----LDATIDALEAQHSTRIGVTAVNPATGEVY-SHRGDERFAMCSTFKAYASAAVLRKTE -DGSTSLDKTVVIEPGDLVENSPVTAAAAGTPMTLAQIAEAALTQSDNTAGNYLLREIGGP -QAVTDLARDVGDGSTRLDRWETELNTAFRDDPRDTTTPNGLAQGFRALLLGDALDTASSD -QLLEWMRASKTSDKRMRAGLPTGWTATDKTGGGGFGTANDAGVAWSPDGAPIVLAILTDS -LTEDAQGNNQAIADTTAAVIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. FJAT-44876 TaxID=2011013 RepID=UPI000BB6D903 -----EEIFGQLEEEYDARLGVYALDTGTGETV-AYRSDERFTYGSTFKPLAVGVLLQQKT ---IDDLDQLITYSSDDLVNYNPITENHVDSGMTLKELSDASIRYSDNTAANLIFNEIGGP -EGFKEGLRAIGDEVTEPERIEPELNDVEPGEIQDTSTPKALALSLQEFTLGDALPADKQE -LLIDWLKRNTTGDDLIRAGVPEGWEVGDKTGAGSHGTRNDIAIIWPPDKDPILLSVLSSK -DELDAEHDDTLIATATEEVIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinicola sp. CPA62 TaxID=1949082 RepID=UPI000DA18E60 ---DLERALAALEARHGGRVGVALMNVATGAVA-SHRGDQRFLFNSTGKFFIAAAVLARVD -SGDESLDRRIEVSQSDLGGWTPITEQHLGSPMTVAELCQAAAAWSDNAAANLLVESAGGP -QRITAFLRGIGDETTRLDRMEPELNAHHEGDERDTTTPLAMMQTIRTLLLGEALSPMSRH -QLAAWMIEGKTGDARLRAGMPTGWLIGEKTGTSGAGNANDIGIAWPGDRGAVIAVAYTYL -PDASKTQRDDVVAEIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075ACF58 ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMSGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MUSC 1 TaxID=1678012 RepID=UPI0009A10F6F -----EAELRALEQWHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --DCAPPDKVIHYPPHDILPNSPRTAEHVDTGMTVADLCAAAIQYSDNAAGNLLLRQIGGP -AGLTRFFRSLGDEVSRLDRWETDLNGAVPGDLRDTTTAEALGGSFARLTLGRALSGADRS -RLVGWLKGNTTSGTRFGAGLPRDWVLADKTGTGDYGTANDVGVAWTTRGTPLLLTVLSAR -TARDAPADDALVAEAARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E64BCC ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKSPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. FY-07 TaxID=1692238 RepID=UPI0007774934 --------VARLEAHLGARIGIAVVDIASGETV-SYRGNERFPLNSTYKALLCGALLSKAD -KGELSLNDTTQFSQSELVEYSPVTSKFVAPAMSWQQLCSAAVSESDNTAANQVTKKLGGP -AAITQFIASSGDSVTRLDRYEPELNSAVPGDLRDTTTPLAVSKTLQKLALGDVLTPRSRA -QLVQWMRDDKVANPLLRSVLPAGWEIGDKTGAGANGSRSIISIVWPQKNKPQIVSIYITE -TNATMAQSNDAIARIGTAIFT-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. JCM 19035 TaxID=1460653 RepID=UPI000AD959C9 --eETAAPFSALEDKYGARLGVYALDTGDGTTV-AYNEDDRFAYASTHKALAVGVMLQQLS ---LEELDRQIRFTEADLVTYSPITEQHLDTGMTLREISDASIRYSDNTAANLVFNEIGGP -AGFKEALRAIGDEITEPERIETELNEVEPGETRDTSSAKALAESLYAFSLGDALDEERKT -LLNDWLIHNTTGDALIRAGVPDDWIVGDKTGSASHGTRNDIGILWPPDEDPIVIAVLSSK -DQADAESDDALIAEATEAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chrestomyceticus TaxID=68185 RepID=UPI000F61D10E -----THRLRELEREHQARIGVFALNLATGATL-LHRAHERFPMCSVFKGLAAAAVLRDLD -HDGTQLSRVIHYTEADVRKHVPITSQHVADGMSVRDLCDAAVRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIAHTYRRLVLGDALNRPDRA -LLTDWLLRSTTSVERFRAGLPKDWKVADKSGGGSYGTSNDAGVAWTPDGTPIVLAVFTHK -PTLPTASGD-------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces angustmyceticus TaxID=285578 RepID=A0A5J4LI23_9ACTN ---ALVGQLRDLEQEYSARLGVFAYDTATGRTV-DYRADERFAMCSVFKGLAAAAVLRDLD -HHGEFLARRIRYTEKYVTDYAPVTGKNVAQGMTVEDLCAAAVSQSDNGAGNLLLRELGGP -TAITRFCRSIGDGTTRLDRWEPELNTAEPWRTTDLTTPRAIGRTYARLVVGDALPAEDRS -RLTGWLVANTTNGERFRAGLPADWRLADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK -YDPKGPTDNPLVARTAALV---- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI000671CD0B ---TFQQSLAKLEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVQGYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRGLGDTVTRHDRYELELNRPHPSEPQDTTTPRAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=A0A0W7Z8M9_9BURK ---SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD -QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP -AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ -QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG -SSAEGAVKDACLADVAAWVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=A0A1X4H788_9ACTN ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE -RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARVAAR-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013D8F4AE -----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVAIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -SALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKSRL -QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. AG209 TaxID=2183909 RepID=A0A397N7Z1_9GAMM ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDLVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK161 TaxID=887463 RepID=A0A4R7IMG1_9ACTN ---STTAEFQELEREFDARLGVYALDTGTGRTV-AHRADDRFAYASTFKALAVGAVLRKYG ---TEGLGKVVAYGRDDVVADSPVTENFAGSGMSLKGLCAATLWYSDNTAVNLLLKELGGP -DGLEKVLEGLGDDVTEMNRYEPEMSEGTPGDVRDTSTPRALAADLRAFLLGDALERDERR -LLRQWMETNVTGDTLIRAGLPDDWTVADKSGTAGYGGRNNIAVVWPEDGNPIVMAVMSTR -GKQGAERRDALIARAATVAVD-- ->[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI0004B3C1B7 ----YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILIDWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFVAILSSK -NAKDAKYDDKTISEASKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Micromonospora sp. CNZ280 TaxID=2586994 RepID=UPI001422C038 -----HHRLTELERRYDARLGVYALATGTGATI-AHRADERFAFCSTFKGLAAAAVLHGNP ---LSHLDTVVRYTEDDLMKSSAITRRHVASGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -ARLTAYLRGLGDPVTRMDRFEPDIVTAIPGDPRDTTSPRAIGADYQQIVLGDALPPDKRA -FLRGLLERNATGAKRVRAGVPKDWTVADKTGTGDYGTLNDIALVWPPGSAPLVISIMSSK -ATREATYDQALIADAAAYVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. paromomycinus TaxID=92743 RepID=A0A401W665_STRRY -----TRRLRELEREHQARIGVFALNLATGATL-LHRAHERFPMCSVFKGLAVAAVLRDLD -HDGTQLSRVIHYTEADVRKHVPITSQHVADGMSVRDLCDAAVRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAVARTYRRLVLGNALNSPDRA -LLTDWLLRSTTSVERFRAGLPKDWKVADKSGGGSYGTSNDAGVAWMPDGTPIVLAVFTHK -PTQPTASGD-------------- ->[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=A0A6B4AS52_CLOBO ----YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILIDWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPPNKKPIFVAILSSK -NAKDAKYDDKTISEASKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE08E57 ----------GIEAKLGARLGLMVVDTETGRQW-QHRSRERFSMASTFKALACAALLDA-- --GETVQSRSMTIEKQDLQDYSPVTGQRVGSQMTAAELCAVTLRTSDNTAANLALAALGGP -KRVTSFLRSIGDTVTRLDRTEPMVNEAKPGDPRDTTTPESMAQSIGDLVLGDALSADARR -QLTGWMEANEVADRLLRAGVPQDWRIADRTGAGGHGTRGIVAVMWPPQRKPVIAAIYLTE -TDASLAERDAAIAEIGRAIAA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JCM 19045 TaxID=1460639 RepID=W7ZAL6_9BACI --dDLTAPFSELEDQYDARLGVYALNTGNGQTI-AFNEDERFAYASTHKALAVGVMLQQLS ---IEDLDKQVTFSEAELVTYSPITEQHVETGMSLREISDASIRYSDNTAANLVFNEINGP -AGFKEALRAIGDDVTEPERMETELNDVNPGETRDTSTPKALAESLYAFSFGDALDKEKQT -LLNDWLIHNTTGDDVIRAGVPDDWVVGDKTGSASYGTRNDIGIIWPPNDEPIVIAVLSSK -DEQDGKSDDALIAEATEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522KC92_9GAMM ---AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD -RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKSVGGP -AAATRFVRSLGDDITRLDRHEPELN--VPDKGLDTTTPDAMLASMRKLLLGNVLSASSRA -QLIDWLRHNTTGETQLRAGMPASWQVGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG -PADQGDMRKAVLAHVGKLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=UPI0009851F3C ---SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD -QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP -AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ -QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG -SSAEGAVKDACLADVAAWVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00022F2FAB ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLVLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3ENW7_9PSEU -------DFAGLERRYDARLGLFAVNVHTGRSM-GYRADERFAMCSTFKTYAAGALLHRNG -LAGGYFDKLIHYTEADLVANSPVTGPNAGIGMMVNELCAAAMTRSDNTAANLMLAELGGP -PAITAFARSIGDGSTRLDRWETDLNTAIPGDERDTTTPAGIAAGYRALVLGDALGAPERD -RLTGWLFANTTGAARIRAGLPPTWRTGDKTGTGDYASGNDVAVTWTDRGQAIVIAVLTTR -PRKDDKVDNGLHADTARIVAA-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI000EFB904E ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLIRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007598C9B ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI0005EF0BA7 ---KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. 60-20 TaxID=1895819 RepID=A0A1M3PIU0_9RHIZ -----EAQLAALESKHPGRICVSVLDMASGKRI-EHRSGERILICSTFKTLAAALVLARVD -KGEEKFDRRVHYTESDLVDSSPATKANVGKGMTIAELCAAMMTLSDNTAGNLLLASFGGP -GALTTFCRSLGDEITHLDRLEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSPASRL -QLAAWLMTNRTGDTRLRAGLPKNWLAGDKTGTNGDGNANDIAVLWPSNRAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces stelliscabiei TaxID=146820 RepID=A0A0L0L8F3_9ACTN ----LAGRLGELEREYSARLGVFAHDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD -RDGEYLARRIHYTEEYVKAYCPITVENVSTGMTVGELCAATVSHSDNGAGNLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALPDADRD -LLTGWLVANSTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK -YDPEGPTDNPLVARAAGLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A357MY60_9GAMM -----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVAIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVSGGP -PALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKSRL -QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia abscessus TaxID=120957 RepID=UPI0009FC8AF2 ---DHHDRLDELEQKFDARLGLYALATGNGTTI-AHRADERFAFCSTFKTLAAAAVLHRNP ---LTHLETVVTYTEDDLLKNASITPRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDIGGP -AQLTEYVRSLGDMVTRMDRIEPAITEATPGDLRDTTSPRAFGTVYQKIVLGDALPADKRD -FLRDLMERNATGAQRIRAGVPQGWTVADKTGTGDYGTLNDIAIVWPTASAPVVLAIMSGK -ATADAAYDQALIAQAAEYVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Leaf396 TaxID=1736363 RepID=A0A0Q5ZGE3_9BRAD -------ELEAYERESGGRVGLYAENLATGRKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPFGQTDLLDYAPVARQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -SALTAFWRSIGDTISRLDHDEPELNRSPPGNPQDTTTPTAMAGNLRRLVTGAALSPGSRA -QLTDWMVNCKTGANRLRGGLPASWKIGDKTGYNGKDAAGDVAVAWPKPETPILIAAYVQG -GSPTAEQIAAVFARMGRMVTE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Root1310 TaxID=1736452 RepID=A0A0T1UP69_9ACTN ----VTDRLRDLEAGHGARLGVFAHNVRTGRSV-RYRADERFPVCSLFKTLAVAAVLRDLP ---EGTPDRRVFWTAADVVENSPVTQEHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP -AALTRFARSVGDRVTRLDRWEPELNSAEPDRITDTTSPYAIGRTYARLVLGDALAPADRR -RLTDWMLGTVTSANRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQLTK -PARDAAYDHELIVETAGLLA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI001124C5AB ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACIRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B7D1A ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIQAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI0006AC5B4B ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia anaemiae TaxID=263910 RepID=UPI0012F4BE07 -------RLAGIEQQHQARLGVFAVDTGSGKTV-GLRQDERFAMMSTFKTLACAALLREHP -LATGYFDQIIHFTEADVAAGSSVTGTRIDSGMSVSELCDAAITRSDNAAGNELLKLLGGP -QALTRFLRSIGDEISRLDRWEPQLNTAIPGDERDTTTPAAIAADYRALTVGDALAAPERA -QLTAWLIATTTGGTRIRAGVPDDWRTGDKTGTGDYGSANDVAVTWPGASAPIVIAVLTTH -SSPDAKVDNALVAEAAKEA---- ->[subseq from] Beta-lactamase n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A1A6X7C2_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA4_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q4W1R9_PSEAI --------VTQEETTLQARVGVAVIDTDSGLTW-QHRGDERFPLNSTHKAFSCAAVLAQAD -RHKLNLEQAIPIERTALVTYSPVTERVPPGGLTLRELCRAAVSISDNTAANLALDAIGGA -RTFTAFMRSIGDDKTRLDRREPELNEATPGDARDTTTPIAAARSLQTLLLDGVLSAPARN -ELTQWMLGDQVADALLRAGLPRDWQIADKSGAGGHGSRSIIAVVWPPKRSAVIVAIYITQ -TAASMSASNQAVSRIGSALAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces auratus TaxID=114687 RepID=UPI000593F658 --dELSRRLADLEQQHSARLGVFAHNTATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTTKDVRDYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TAITRFCRSIGDGTTRLDRCEPDLNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -RLTGWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLTWPPSRSPIVMAVLTTK -REPDATADNPLVAKTAALLAK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=D2ARB3_STRRD ----ARKELRTLEASFKGRIGAYAVDTATGKTI-TYRSGERFPLLSTFKAIAAAAVLHKAR -TDPGLLNKVVHWTTAELQEHSPVTGKHVKDGMTVARLCEAAITRSDNTAANMLLKQIGGP -AGLTAYFHTLKDPVSRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALDARDRE -RLNAWLTANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDIAVVWPGKSAPIIMSIYTNR -GAADAAVDDKVIADTAAILA--- ->[subseq from] Beta-lactamase n=2 Tax=Mitsuokella TaxID=52225 RepID=A0A414NZB9_9FIRM -----LHELEDLEQQYQAVVGVYAIDTETGRTI-AYHEDKRFSYCSTHKALLAGAILQHFS ---LADLNEVIHYSADDILSYAPVTKNHISEGMTLGSLCEAAIRVSDNTAANLMMQKLGGP -KVFKDCLQEIGDKTTRPVRLEPELNTR--DGKKDTSTPRQLALDLQAYALGDVLTDEKKA -LLLDWMQGNATGDNLIRAGVPEGWQVADKSGSGAYGTRNDIAVIYPPDRKPIVLAILTTH -KDRDAKTDDALVAEAAGIIVK-- ->[subseq from] TEM beta-lactamase n=2 Tax=root TaxID=1 RepID=I0AXX0_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAAL---------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI000F45B1A6 ---QLAETVAKTESRLNARVGVVLYDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD -AGTLTLDEELPVLQSDIVSYAPVTEKKVGQTMPLSELCLATIDMSDNTAANLLINRLGGT -EAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLGDVLSPQSRN -QLIEWMSHGGVTGALLRKIAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD -VKADFATRNGALQDISAAVI--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. Betaine-02u-21 TaxID=2058301 RepID=A0A2N1GL59_9GAMM ----TAADFAALEKASGGRLGVTLLDTRTGKRV-GHRQDERFPMCSTIKWMLAAAALHRAE -RQPGFLDERLPMRAEDLIDHAPTTRRHVGKDLSVRDLCRTTMVTSDNPAANLLLRHLGGP -PALTAFMRSHGDAVTRSDRYEPELNRFTLGDPRDTTSPAASAASLQRFVLGDALRPASRQ -QLADWLIDNETGDATLRAGLDKRWRVGDKTGSNGKDTRNDIGVLWPLGGTAWVLTAYLQG -ASVDGGQRDAVLARVAALA---- ->[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI00099D6564 ----YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVAIPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVMPPNKKPIFVAILSSK -NAKDAKYDDKTISEASKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TP-A0356 TaxID=1359208 RepID=UPI0006E4288C ---SLSKEFRTFEQRYGARLGVYARNVRTGRTV-AYRAGERFAMCSTFKAFAAAAVLRDHG --DCAPLDRVIHYPLRDILDNSQYSEDHLATGMTVGQACAAAIQYSDNTAGNLLLRQVGGP -QGLTRFFRSLGDQVSRLDRWETDLNTATPGDQQDTSTPQALGTSFERLTLGRALARTDRE -QLVTWLKGNTTSDKRFGAGLPRDWALADKTGTGSYATANDIGIAWTTRHTPLLLTVLSTK -DARDAPVDNDLIRDAAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. WAC 06369 TaxID=2203193 RepID=A0A429G0X0_9ACTN ---EVGKRLHRLEAERNLRIGAYAIDPATGAFV-SHRADERFPYTSTFKAIACGGVLQKAR -TDPGLMERVIRYTEDDLVDWSPVTEDHVGTGMTVSALCHAAITQSDNTAGNLVMKQLGGP -AGLTRFFRSLGDGASRADRWETALNDWKPGERRDTTVPSTWAANLHKLTVGDALVPEDRE -QLIAWMKANTTGDKRIRAGLPDSWTIGDKTGTGGYGNANDIAVAWPPGRDPLVMVIMTTA -KKEDAEADDAAVAETAAILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B0FB3 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAALVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI000585BFDD ---KLNEDLSAIEDHITGRIGVSVWDTQTGEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLEKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces seoulensis TaxID=73044 RepID=A0A4P6U1D5_STRSO ----LRPELAELEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPADILSNSEHSQARQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSHGDRE -QLVGWLRGNTTSAKRFGAGLPSDWVLADKTGTGSYASANDLGVAWTGKGTPLLLSVLSTR -PAPDAPVDEALIEETARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Gracilibacillus lacisalsi TaxID=393087 RepID=UPI000475A6B6 -----DEEFAQLEDEFETQLGVYAIDTGENQIV-EYNPDERFAYASTFKVLAAAILLKQNE ---IKDLEEVVTYSKDDLVTYSPVTENHVDTGMTLLEISEAAIRKSDNTAGNLLLEALGGP -DEFQALIQDLGDDVTEPERYETELNEFMPGNKSDTSTPKVLATNLKKIALDDFLPNDKRE -LLMDWMKGNATGDKLIRAGLPEEWIVGDKSGAASYGTRNDIGIVWPPDREPIIIAVMSRH -DTKDAEYDDELVAKAAGVIFD-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011210319 ---KLNEDISLIEKQTSGRIGVSVWDTQTDKRW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAENLVLNEIGGP -KAVTQFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751FC07 ---AAQAQLDALEQASNGRLGVAALDTASGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEVARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=A0A1V0BC14_9BURK ---SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD -QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP -AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ -QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG -SSAEGAVKDACLADVAAWVAQ-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084A7C52 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAVIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Actinotalea fermentans TaxID=43671 RepID=A0A511Z0R8_9CELL ----VSAELAALEAELGVRIGVHALDTATGRTA-EYRADERFAYASTFKALAAGAVLAAAD ---DAALAEVVPYGPGDLVTYSPVTEAHAGVGLPLSEVLRAAVQESDNTAANLLLARLGGP -AGFAEALRALGDDVTQPVRIEPDLNAWSPGDPKDTSTPRALATDLHAYVLGDALDDADRA -LLVGWMRASTTGTALVRAGVPEGWTVADKSGQGSHGTRNDLAVVWPPGGEPIVLAVLTSR -DAPDAEPVDAAVARATAVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. UNC378MF TaxID=1502748 RepID=A0A1G5UD01_9RHIZ -----EPDWGAIERRLDGRLGISAAT--EDRVLsAYRADERFPMCSTFKVLAVAAVLARVD -AGRETLDRIVAYGPGDLLSYAPVTRAALEAGMRVSDLCSAAIVWSDNTAANLLLASLGGP -EALTAWLRGTGDPVTRLDRTEPTLNTALPGDPRDTTTPGAMRTTLGRILLGTVLSSASRG -RLDAWMGACETGRKRLRAGLPSDWIAGDKTGSGDNGSVNDVAILRPPGHAPVLVAVYLTG -STASAENIAAAYAEIGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 1222.2 TaxID=1938833 RepID=A0A286EXY6_9ACTN ----LAGRLGELEREYSARLGVFAHDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD -RDGEYLARRIHYTEEYVKAYCPITVENVSTGMTVGELCAATVSHSDNGAGNLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALPDADRD -LLTGWLVANSTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK -YDPEGPTDNPLVARAAGLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI00130DD8C1 ---DIDVRLAALERKTGGRLGVSVLDTETNIGF-DYRETERFPMLSTFKTLAAACVLARID -QNEDALERRIRFSKDDLVTYSPVTEKFVDGEMTLSAICAAAITLSDNTAGNLLLAQVGGP -QGLTAWLRSIGDAVTRLDRTEPTLNESLKGDARDTTTPSAMRETITSLIAGDALSPSSRD -HLLGWLVANKTGDQRLRAGLPGDGLIGEKTGTTDKGGACDVGLFQPARRQPIFISAYVAE -ATVPVKELNPVFSEIGRMVTE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SCA2-2 TaxID=1563677 RepID=A0A4Q6V4P0_9ACTN ---DAERRLARLERESGIRLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -QNGEFLSRRIFYTRDDVEQGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP -TAVTRFVRSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPEDWVLGDKTGAGRYGTNNDAGVTWPPGRPPIVLTVLSAQ -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea pusilla TaxID=46177 RepID=A0A1H7ZLV3_9ACTN ---SARKELRALEKTYQARIGAYALDTGTGKTV-AYRAGERFPLLSTFKALAAAAVLHKAR -TDPGLMNRVVTWTQDEVKPNSPETEKHVKDGMTVAELCRAAITKSDNTAGNMLLKQLGGP -SGLTRYLRALKDPVSRLDRWETELNLWSPKERRDTTTPAALARDLRALTVGDALAPEDRE -RLNGWLRANETGDTRIRAGLPPTWTVGDKTGTGTYAANNDVAIVWPADAAPVIIAIYTNR -DTAGAAREDEIVSRTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FN55_9PSEU ------ADFEQLERAYRARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---VADLDRTVTYERKDLVVNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP -AGLNAVLRAIGDTTSHADRIEPELNDTAPGDTRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTASYGTRNDIGVVWPPGRAPIVVSVLTDR -SEKDAGIDNKLLADATAAAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Salibacterium halotolerans TaxID=1884432 RepID=A0A1I5SE59_9BACI -----DEKFAQLENEFDAQLGVYAMDTGTNQIV-EYRPDERFAYSSTFKPLAAAILLKQNN ---IEYLEKVVTYTSDDLVAHSPVTKKHVDTGMSLLEISEAAIRKSDNTAGNLLLEAIGGP -VKFEQALRDIGDDTTQSERYEIELNKFTPRNKRDTSTPRAMAANLNKVALSDFLSNNKRE -LLIDWMTGNEAGDPLIRAGAPEKWKVIDKSGAGTYGTRNDIAVVWPPNKEPIVIAIMSRH -DTKNAEYDDALIAKAAEIS---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Tu 2975 TaxID=2676871 RepID=UPI001357D003 -----HERLAELERTYDARLGVYALATGTGEVI-AHRADERFAFCSTFKGLAAAAVLDRNP ---LSHLDTLVRYTEADLLENAAVTPRHVSTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYARGLGDTVTRMDRIEPLITEATPGDPRDTTSPRAFGSDYRKIVLGDALPPAKRA -FLRDLLERNATGAARVRAGVPKGWTVADKTGTGSYGTLNDIAVVWPPKSAPLVISIMSSK -ATEDAAYDQTLIAEAATYAV--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFB0_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLAKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075E8A81 ----AQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. P1-11 TaxID=2024616 RepID=A0A5A7ZYL1_9RHIZ -----EPDWGAIERRLDGRLGISAAT-ADRVL-sAYRADERFPMCSTFKVLAVAAVLARVD -AGRETLDRIVAYGPGDLLSYAPVTRTALEAGMRVSDLCSAAIVWSDNTAANLLLASLGGP -EALTAWLRGTGDPVTRLDRTEPTLNTALPGDPRDTTTPGAMRTTLGRILLGTVLSSASRG -RLDAWMGACETGRKRLRAGLPSDWIAGDKTGSGDNGSVNDVAILRPPGHAPVLVAVYLTG -STASAETIAAAYAEIGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. NRRL S-836 TaxID=1519492 RepID=A0A0M8WJV0_9NOCA -----TGRLRDLEQQHGARLGVFASDTGSGRTV-LYRSNERFPICSVFKTLVAGAVLRRDQ --DGALLDKVLRYTQAEVDKYGPITGKNLANGMTVRALCEATITYSDNAAANLLLRELGGP -SAVTRFCRSIGDPVTRLDRWEPELNSAEPWQECDTTSPRAIGQSYARLTVGHALERPDAR -QLTDWLLANTTGANRLRAGLPGEWRLGDKTGTGSYGTTNDVGITWPPGRAPIVVAVLATK -PAPKAGADEPLVAKAAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNR698 TaxID=1206101 RepID=UPI000483DF8A -----VREFTELEDRFEARLGVYAVDTGTGQEV-AHNEDERFAYASTFKVLAAGAVLREHS ---LSGLDQVITYSADELVPHSPVTAKRVATGMTLAELCDAAVRLGDNTAANLLLDELGGP -RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALARDLRAYVLEDALGKGERA -QLTEWLRTSATGSELIKAGVPKDWMVGHRAGAGGYGVRNDIAVVWPPDSAPIVMAIMSNG -LRRDADHDDRLIAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=UPI0004107226 --------FEAYERETGGRIGLYAEDVATGAKV-TWRTDERFVMCSTFKASLAACVLARID -RGEDQLENVVRYRAADLLHHAPAARQNLASGMSVADMCKAAVELSDNTCANLLLARIGGP -AALTAFWRDTGDTVSRLDHYELELNRSPPGDPHDTTTPAAMAGNLRHFVLGEVLSPASRE -RLTDWMLNCKTGNNRLRNGLPKDWKIGDKTGNNGKDAAGDIAVVWPRKGGPVLISAYTQG -GSPTAQQLEAVFAAIGQMIGRRf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V781_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces auratus AGR0001 TaxID=1160718 RepID=J2K7Y9_9ACTN --dELSRRLADLEQQHSARLGVFAHNTATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTTKDVRDYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TAITRFCRSIGDGTTRLDRCEPDLNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -RLTGWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLTWPPSRSPIVMAVLTTK -REPDATADNPLVAKTAALLAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. Alg238-V104 TaxID=2305993 RepID=UPI0013D564B4 ---ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP -GALTEFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA -QLAAWMIANKTGDRRLRAGFPANWLVADKTGTSGLGYSNDIGVAWSPARGAVLVTVYCEM -PKAEAEARDRIIAEVAEMV---- ->[subseq from] Uncharacterized protein n=1 Tax=Caulobacterales bacterium 32-69-10 TaxID=1970503 RepID=A0A258FCR5_9PROT ---EAEPQIAALEARYGGRLGFMALDTGSGRRI-AYRADERFNTASTFKWLLAAAVLARVD -RGAERLDRRIAYTRADLLGVSPVTEANVARGLSVAELCAAIVEVSDNAAANLLLASIGGP -AALTRWLRSQGDPVTNMVRNEPTLNSAIPGDARDTTSPAAMVGNLQRLVLGAALSAPSKA -RLIDSLTASRTGLKMLRAGLPADWRVGDKTGRGANASVNDVAVAWRPSGAPVLMAAYLTT -GDG--GAADGVIADLGRLVGARf ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A165E8R5_9MICO ---EADSAFTQLEDDFDARVGVYAVDLDTGREL-AWRGDERFAYASTIKAMASAALLDEVG ---TDGLSKRVSISEDDIVSHSPVTETKVGGTMTLAELCEAAMTQSDNGAANLIFAELGGP -AALDERLNDLGDTGTTVSRTEPGLNEAKPGDPRDTTTPRASAGNLREYVFGGALEDDEAT -TLTDWMKATQTGDTLIRAELPEEWTVGDKSGTGYYGSRADLGIVWPGDGGPIIISVLSSK -DEKDAEADDRLISGAAAIAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID14446 TaxID=2706072 RepID=A0A6B2YNK3_9ACTN ------PSFARLEREFDARLGVHAVDTGTGKAV-AYRPDEPFAFASTYKALAAGAVLRRNT ---PAGLERVVTYTQAELVAHSPVTGRHVESGMSLRALCDAAIRYSDNTAGNLLLGELGGP -KGFQAELTGLGDTTTRADRYEPALNEAAPSDPRDTSTPRALTSALYAYTLGGVLDGERRA -LLLDWLGRNTTGGALIRSGVPAHWKVGDKTGNASYGTRNDIAVVSPPGAAPILLAVLSSR -AARDAAYDDRLIARATEVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2F3N9_9ACTN ---RAKKELRDLEKSLGVRVGAYAIDTATGRTI-GYRSGERFALASTFKAIAAAAVLHKAR -TEPGLMDKVVKWTADEVKPNSPITEKHVEDGLTVAQLCHAAITRSDNTAGNMLLKQLGGP -AGLTRYFRTLKDPVSRLDRWETELNDWSPKDKRDTTTPAAIARDLRLLTAGDALSAKDRE -RLNGWLLANTTGGARIRAGLPASWTVGDKTGTGGYGTANDIAVAWPKKGAPVIMAIYTNG -RTPGAAAQDKALADTATILA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0009A17B2E ------ADFAALEKASGGRLGVTVLDTGSGRRIaGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRISLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -PALTAFLRAQGDAVTRNDRYEPEMNRFAKGDPRDTTSPAAMAASLARFAVGNGLSAASRL -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGAPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI00066A15E7 ----AAADFAALEKACSGRLGVTLLDSADGRRL-GHRQDERFPLCSTFKSLLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWILTAYLQA -GAISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A5N0KTQ6_STEMA -----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLHLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVSGGP -PALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKARL -QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDVAVLWPRGGTPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA0_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -AAVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas taiwanensis J19 TaxID=935569 RepID=A0A562E2Z8_9GAMM -----APDFAALEAASQGRLGVAVLEAGNGRYLaGHRADERFPMCSTFKALLAAAVLARAD -RGALDLDERLPVRAADLVPHAPVTRRHVGKDLGVRDLCRAIVTISDNTAANLLFARIGGP -AALTAFLRGLGDTVTRSDRLEPEMNGFVPGDPRDTTSPRAMATSLRRCVAGAVLAPASRL -QLADWLIDNTTGDDCLRAGIGPEWRVGDRTGSNGTDIRNDVAVLWPLAFQ---------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2S1FM51_ACIBA -------------------VGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYL-- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754EC53 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI000459B5C7 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAICYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_031 TaxID=2175622 RepID=A0A2W1R3E2_9MICO ---ATARAFGALERRYDARLGVVAIDTGSGRTI-AHRAGERFAFASTVKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTSEHVDTGMTVRELVDAALRSSDNTAANLLVGRLGGP -GAVERWLRGIGDRTTSVDRVEPDLNQAVPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVMTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis benzoatilytica TaxID=346045 RepID=UPI0003687BA8 ---AAQPDFSQLEKAFGARLGVFAIDTGNGREI-AYHADDRFAYASTHKVFTAAAILHRGE -----DLNRMITIRKSDLVPNSPITEKHLDTPMSLRSVLDAALRYSDNTAGNLMFREIGGP -AGLSSDLRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRIWAADLRAAALGSGLPTDQQA -VLTGIMRASTTGTNAIRAGVPADWQVADKTGTADYATRNDIAVLWPPHRAPIVLAVLSDH -AQKDAKTDDKLIAQAASAVAK-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011231162 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPIYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-47 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000400F856 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDESNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104IBK7_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=A0A243QV82_9ACTN ---RARKELRTLEASFKGRIGAYAVDTATGKTV-AYRSGERFPLLSTFKAIAAAAVLHKAR -TDPGLLNKVVHWTTAELQGHSPVTEKHVKDGMTVARLCEAAVTQSDNTAANMLLKQIGGP -AGLTAYFRALKDPISRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALNAKDRA -RLNAWLIANKTGDARIRAGLPKSWTVGDRTGTNSYGAGNDIAVVWPGKSAPIIMSIYTNR -RAADAAADDKVIADTAAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas cupida TaxID=44933 RepID=A0A1M7JSN2_9GAMM --sDLQARLAELEQQHNGRLGIALMNLATGAVA-SHRGDERFLFNSTIKVIIAATILARVD -RGESALDRRLVVAESDLGGWTPITEQHLGEPMTVAELCQAAVAWSDNAAANVLFRELGGP -AAITDYLRTIGDDVTRSDRIEPALNEDHDGDERDTTTPLAMLQTLRALLFGDTLSPQSRH -QLVAWMVEGKTGDNRLRAGMPSSWLVAEKTGTSSGGNANDIGVAWPMDRGAVIAVAYTWL -PDAEPEQRDEVVAEVGKLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=UPI000D97E685 -------RYAALEREHGARLGVFAVATGTGATV-AYRAGERFAFCSTFKTLAAAAVLHRHP ---LAHLKDRVTYTRADIDSISPVTEDHVATGMTIRQLCDAAIRFSDGTAGNLLMRDIGGP -AGLTAYLRELGDGVSRMDDYEPELNRVRPGDPRDTTTPRAIAEDYRGLVLGTALPPDKRA -LIKDWLERSTTGAKRIRAGLPGGWKAAEKTGTGDYGRANDIAVVWPPRAAPLVVAVLSDR -PGRDARPDDALIAAATRRIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FA94A ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759D6A1 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3S3T0_9PSEU -------DLLALERKFDARLGVYALATGTGTAI-AHRADERFAFCSTFKALASAAVLHRNP ---LSYLDTLVTYTEADLMKSARITREHLTTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -AELTAYTRSLGDAVTRMDRFEPMITEATPGDPRDTTSPRAIGTDFHRIVLGDALPTDKRA -FLRDLLERNVTGAKRIRAGLPSGWAAADKTGTGDYGTANDIAVVWPPNGEPLIISIMSSK -ATKDAEYDEALLAEATANVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007557B05 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Legionellales bacterium TaxID=2026754 RepID=A0A2E3MGJ4_9GAMM ---AADEKLAGLEHSFNGKIGVYAIDTNNGNII-AHRADERFPFQSTFKTIAAGALLYQAK -TDDDLLNERITYSQKDLVGWTPITKQHVKDGMTLEELAEAAVSYSDNGAVNLIMENLGGP -EAITRFANAIGNASFNVTNYEVNLNSN-PYDTSDTSTPKDMAISLQKLTLDDVLSPENKQ -KLTTWLTNNTTGNQRIRAGVPIGWTVADKTGSGDYGVANDIALAWSPFCKPIVISIYTNQ -TDSDAKNRDDIIAQTTEIVFA-- ->[subseq from] Beta-lactamase n=3 Tax=Mycolicibacterium smegmatis TaxID=1772 RepID=Q7WVE1_MYCSM ----VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAARILRGAE -RGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLKQIGGP -AEITAFARSIGDQRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQ -LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT -RGPNADGFRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium smegmatis TaxID=1772 RepID=A0A0D6HY69_MYCSM ----VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAARILRGAE -RGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLKQIGGP -AEITAFARSIGDQRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQ -LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT -RGPNADGFRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000757B9F2 ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVAAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Salinicola sp. TaxID=1978524 RepID=A0A2D8P0U4_9GAMM ---DVQRKLEALEQRHGGRLGVALMNVATGAVA-SHRGDERFLFNSTGKGFIAAAVLARVE -RGEESMDRRIEVSQADLGGWTPITEKRIGSPMTIAELGQAAVAWSDNAAANLLIESVGGP -ESVTAFLRGIGDDTTRLDRMEPALNEDHEGDERDTTTPLAMMQTLRTLLLGEALSPSMRH -QLASWMIEGKTGDARLRAGMPAGWLIGEKTGTNSVGNANDIGIAWPADRGAVIAVAYTWM -PEASKAQRDQVIAEIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI0003118950 -----HDRLIELERKFDARLGVYARATGTGVTV-AHRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVVTYTRDDLLKNATVTPRNVDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP -AELTAYARSLGDPVTRMDRIEPAITEATPGDPRDTTSPRAFGEVYHRIVLGDALPGDKRD -FLRDLLERNATGAQRIRAGTPQGWRVADKTGTGDYGTLNDIAVVWPPDAAPLVVAIMSSK -ATRDAAYDQALLAEAAAYVMD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0005DA5757 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=A0A2N3XYC7_SACSN --------FADLERRYDARLGLFAVNVHTGHVL-DHRADERFAMCSTFKTYAAAALLREHG -LDSGYFDKLIHYTEADLVAGSPITKPSAGTGMLVHELCAAAINRSDNTAANLLLAELGGP -AAIAPFARSIGDGSTRLDRWEPDLNTAIPGDERDTTTPGGIAAGHRALVVGDALGGPERD -RLTGWLFTNTTGGKRIRAGLPPTWRTGDKTGTGDYASANDVAVTWTDKGHPIVIAVLTTR -PRKDDEVNNGLHAETARIVAE-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI000769EABB ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACAAMLKDMD -SEKLDKNATAKVEERSMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID1328 TaxID=2690250 RepID=UPI00136A5561 ---ALRPELAALEKRYGVRLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG --GRAALGEVIHYPPADILSNSEQTKAHQETGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDARDTTTPRALGRTFELLTLGEALSDCDRE -QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTPLLLSVLSTK -PAPGAPVDEALIEETARLLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104TBG5_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TR1341 TaxID=2601266 RepID=UPI00138B08A2 ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQASGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE -RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DPD3_9PSEU --------LTELERKFDARLGVYALDTGSGAAI-AHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTAVTYGEGDLLKSAVVTRENVATGMTIGQLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYTRGLGDTVTRMDRVEPHIVEATPGDPRDTSSPRALGTDYQRIVLDDTLPAEKRE -YLSDLLVRNTTGADRIRAAVPQGWTVADKTGTGDYGTLNDIAVVWPPDRAPLVVAVMSSK -ALPDAEYDEAVIAEAAAFVL--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium pseudosasicola TaxID=582667 RepID=A0A1I4S0G7_9RHIZ --qETELALTAIERRLGGRLGVSVG-TQAGVLL-SHRVDELFPMCSTFKVLAAAAVLARID -AGTDSLDRVIAFGPGDLLSYAPITRKTLDAGMTLSELCAAALEWSDNSAANLLLTALGGP -EALTRWLRSIGDPVTRLDRDEPTLNTALPGDPRDTTSPAAMRDTLGRVLLGSVLSAASRG -RLEAWMVASRTGLKRIRAGLPPDWPVGDKTGTGDNGTFNDVAILRPPGHAPVFACVYITG -AQVPAEAVEAAYAEIGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium canettii TaxID=78331 RepID=UPI0002A5959F ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREGLLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758B611 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751BB27 ---TAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BFB28 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis complex TaxID=77643 RepID=UPI0008A8BAB0 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVGRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000760499C ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007535C1F ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007595FB2 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio jasicida TaxID=766224 RepID=UPI000CE55E0E ---KLNEDLASIEEHISGRLGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMVGQTTRIEHACEATMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLEEy ->[subseq from] Beta-lactamase class A n=1 Tax=Caenispirillum bisanense TaxID=414052 RepID=A0A286GA81_9PROT ------ARLADLERRHGGRLGVTILDVATGART-GWRQDERFLACSTFKALLAAHVLRRVD -AGQETLDRRIPVGKADLVPWSPVAETFVGTPMTVAQLCDAAVTMSDNAAANLLHAASGGP -AALTAFVRGLGDAVSRFDRTEPALNEDHAGDERDTVAPASMAATLHALLFEEALSRRSRD -LLRGWLVTNRTGDARLRAGFPATWLVGDKTGTNGSGTAADVAAVWPNTRPPLVVTAYYEV -RGASADARNAVLAEVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075972A0 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces violens TaxID=66377 RepID=UPI0004BF7DE0 ----LSGQLKRLEREHAARLGVFARDLATGRTV-RYRADERFPMCSVFKGLAAAAVLRDLD -HDGEFLAKRIHYTKKYVTDYAPISSENVAHGMTVTELCAAAVSHSDNGAANLLLRELGGP -TAITRFCRSLGDDETRLDRWEPQLNSAEPWRTTDTTTPRAIGTTYGRLVVGRALAAEDRK -RLKDWLIANTTNTKRFRAGLPDGWITADKTGGGSYGVANDVGVAWPPGRSPVLLSVLTTT -HAPEGPSDDALVAKAAELVA--- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009EC2150 ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDCCIAEVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella ureilytica TaxID=2530374 RepID=A0A4R4RNX3_9ACTN ---AVAAALAQLETDYAARLGVYAVDTGTRETV-EHRADERFAFASTHKALSAAAVLQATD ---AAALDDVIQYDAADVVGHSPVTEPAAGTGLTLLEVIRAAITVSDNTAANLLFEQLGGP -DGLEAAVRGFGDDTTSFDRIEPGLSDWAPGETRDTTTPRAMAANLERLALGDLLAADDRA -VLVDAMRDNTTGDELIRAGVPDGWPVADKTGSAGHGGRNDIAVIEPPDSAPIVLAVYSNR -LDPEAESDPALIAAAATIVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0013DA16C7 ----LSGRFRALEKRYGARLGVYAHDPRSGRTV-RYRADTLFPQCSLFKTLAAAAVLRDLD -RDGEVLARRIRYTEADLVEGSDHTRENLATGMTVAALCDVAIRFSDNTAANLLLRELGGP -TAITRFARSTGDRVTRLDRWETELNSAEPWRTTDTTSPSAIGRTYARLVLGDALNRCDRS -RLTDWLLRNKTSGTRLRAGLPGTWTVADKTGGGPYGTNNNVGIAWTDDGSPLVLSLLSRM -PERDAVKNDALIAGAAAVLAD-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001302D56F ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLVLEHy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02261 TaxID=1703940 RepID=A0A1Q5IZS5_9ACTN ---RLVGRLRELERRHSARLGVFAHDVRTGRSV-AFRAEERFAMCSVFKTLAVAAVLRDLD -HDGTFLERRIRYTEAYVERYSPRTEENLAHGMTVAELCDATLRHSDNTAANLLLRELGGP -TSVTRFARSVGDLTTRLDRWEPELNSAEPWRRTDTTTPRAIGLTYGRLLLGDALPREDRN -RLTGWMLANTTSGERFRKGLPADWLLADKTGGGRYGGNNDAGVTWPPDGGPIVLVVMTTR -FEEDAPPVDALVADAAALVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag109_O5-1 TaxID=1938851 RepID=A0A3N4SL02_9ACTN ----AASRFQALEREHRARLGVFAWDTGSGARI-RYRCGELFPMCSVFKTLAVAAVLRDLG ---EEVLAEVVHYDERDVERGAPVTGKNLASGMTVAELCAAAIEYSDNTAANLLLEQLGGP -VAVTRLCRSLGDEVTRLDRWEPELNSAEPGRVTDTTTPLAVGVSYARLVVGDALDGADRR -RLTGWLRANTTGGERIRAGLPGDWTVGDKTGTGGYGTANDVAIAWPPGRAPVVLAVFSTH -IEATAQADSPLARKAAAVVTDAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075A2F93 ---AAQAELAALEKASSGRLGVAALDTSNGTRV-AYHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium botulinum TaxID=1491 RepID=UPI0007DFB8A9 ----YNSAFSKIESDYGVKLGVYAFNTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILINWMSGNATGDKLIRAGAPKDWIVSDKSGTGSYGTRNDIAIVIPPNKKPIFVAILSSK -SAKDAKYDDETISEASKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758068C ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. SWH-M5 TaxID=1490483 RepID=A0A1Q4TPE1_9MYCO --------IADLERRHNALIGIFAANLDSNRTV-AHRADEPFAMCSTFKTYLAARVLQKAE -RGELSLDDRVFVDPSVLLVNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLTKIGGP -AEITAFARSIGDQRTRLDRWEIELNSAIPGDPRDTSTPAALGGGYRALLAGDALSPPQRQ -RLDEWMRANQT--SSMRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLAVMTRS -RDDDAPGLRPLIGEVTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Nocardia TaxID=2637762 RepID=UPI00135AC3BF -----HDRLIELERKFDARLGVYARATGTGATI-AHRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVVTYTRDDLLKNAAVTPRYVDTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYARSLGDMVTRMDRIEPAITEATPDDPRDTTSPRAFGEVYDRIVLGDALPVDKRD -FLRDLLERNATGAQRIRAGVPQGWKVADKTGTGDYGTLNDIAIVWPPDSAPLVVAIMSGK -ATRDAAYDQALLAEAAAYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N5WJ81_9ACTN ----HHDHLASLERKFDARLGVYALATGTGATI-AHRADERFPFCSTFKGLAAAAVLHRHP ---LSDLSSVVRYTRDDLMESSVITRQHVARGMTLRQLSDAAVRYSDGTAGNLLLRDLGGP -RELTAYVRGLGDTVTRMDRIEPAVASAIPGDPRDTTSPRALSTNYQHIVLGEALPPDKRA -FLRDLLERNATGAQRIRAGVPRGWTVADKTGTGGYGTVNDIGVVWPPAAAPLVIGIMSSK -AEKDTEHDQALIAEAAAYVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FEAD73 ---AAQSQLDALEQGSNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDTSLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A244 TaxID=2137016 RepID=A0A2T4NJW8_9ACTN -------RLADLERAYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRT ---LSGLDRRVTYTKADLRSTSPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -PKLTAYLRSLGDEVSRMDHYEPELHDVPPGDPADTTTPQAIATDFRRLLLGTALPARERR -LLMDWLSRNGTGARRIRAGLPGGWKVADKTGTGDYGRANDIAVVRPPRTEPLVLAVMTDR -SGRDAEPSDALIAEATRRT---- ->[subseq from] class A beta-lactamase n=1 Tax=Thermomonospora catenispora TaxID=2493090 RepID=UPI00111DCE32 ---EVQRRLRALEAGYNGRIGAYAIDTATGRTV-GYRAQETFALNSTFKALACAAVLHKAR -TDPGLLDRVIRYTADDLVEYSPETEKNLRSGMTVSALCEAAITLSDNTAGNLILRQIGGP -AGMTAFLRSLGDHRSRLDRWETDLNDWRPGEYRDTTTPALMAQNLRKVTTTDALAEPDRA -RLIAWMRANTTGDARIRAGLPADWTIGDKTGTGRYAPAADIAIVWPKGAAPLIMAIYTNR -TTPDTEVDDRVIARTATVLAQ-- ->[subseq from] Uncharacterized protein n=2 Tax=Xenorhabdus TaxID=626 RepID=A0A2D0KBP5_9GAMM --kQIINQLTALEQSANGHLGVVLINSADNSTI-GYRANERFPLCSTSKFMAVSALLKKSE -TDENLLKQRVNYKQSDLVEYSPITGKYIETGKTLAELSAATLQYSDNTAMNLIINQLGSP -ERVTTFARTLGDMMFRLDRKEPELNLVQPGDERDTSTPQAMAESLYKLALGDFLATNQRT -QLVEWLKGNTTGNASIRAGVPKDWIVGDKTGRCDYGSTNDIAVIWPSNRAPLVLVTYFTQ -PGKNAKARPDVLAEAARIIIQ-- ->[subseq from] BlaL family class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5053 TaxID=1463854 RepID=UPI0004C538D3 ---AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS -AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLGGP -KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE -QLNDWMSGNATGDALIRAGVPKDWKVADKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG -DTEDAEPHDELVAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Crossiella equi TaxID=130796 RepID=UPI000A3A1F09 ------AAFDALEREFDARLGVYARHTGTGAEL-AHRADERFAFCSTFKALATAAVLHRNP ---LSHLDTLIRYGKGDLMRNGPITARNVERGMTIRELADAAVRFSDGAAGNLLLRDLGGP -AELTAYARSLGDDLTRMDRVEPFITEATPGDPRDTTTPRAFGRCFEKVVLGDALPPDKRA -VLRDLLERNTTGDKRIRAGLPPGWRAADKTGTGDYGTANDFALVWPPDGAPILIALMSSK -ATKDAAYDQALLAEAATAVTRAf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA8_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-GHRQDERFPMCSTFKSMLAATTLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGVDMTVRDLCRATIITSGNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides saopaulense TaxID=1578165 RepID=A0A1S4VW56_9MYCO ------NEFAALEKNFGGRIGVYALDTGSGRTV-GHRADERFLMCSTVKTFIVSAILHRRR -SVPSLLDKRIQYTQADLLEWAPITSQHVAEGMSVSQLCDATIRYSDNTGANLLIAELGGP -KETEKFVRGLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPSGWTVGDKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP -EDPKSTQGKPTIAAATRIALQAf ->[subseq from] Carbenicillin-hydrolyzing class A beta-lactamase CARB-41 n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A646LGQ0_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=2 Tax=Arthrobacter sp. PAMC 25486 TaxID=1494608 RepID=A0A0A1CSU8_9MICC -----DTEFVALEKKYDARLGVFAVDSRTNAAV-SYRADERYAFCSTYKALAAAAVLNQRT ---VHELDEVIHYAREDLVAYSPVTEKHLEQGMTVRALCEAAVRHSDNTAGNLLFQELGGP -QGLNGKLRELGDDVTQMDRVEGALNSAVPGELLDTSTPRALANDLRHYALGSGLSAEKSA -IFNDWLEGNATGANLVRAGVPQEWKIGDKSGAGAYGTRNDIGIIHPPAGNPICIAVLSTR -TTPDATYDDKLIADATRIAVQH- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0002E25444 ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLRTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Acuticoccus sediminis TaxID=2184697 RepID=UPI000DAC2C51 --dRLADTIRTLETDIDARIGVLVRDSASGWEW-GHRQDERFLMASTFKSLLCGAVLAQVD -SGALSLDEPIEIGEEDMVEYAPTTEKHIGGSMTVGDLCFATLDLSDNPAANLLIERLGGP -QAVTAFARSTGDEVTRLDRFEPELNVFDPDDPRDTTSPTAMLSTWEAMLRGDALSATSRD -QLEEWMSHGGVTGKLIRAETPDGWTVADKSGSGEGYTRNLVAMVTPEDRPPYFVAIFVSD -SPTDFTTRNGALSRIGAAVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea sp. NGS-ED-1003 TaxID=1526743 RepID=UPI0005341117 -------VAQQEEQALKARIGIAVIDTGAESVA-SYRGNERFPLNSTHKALLCGALLSAQE -QCKLRLTERTQFDRAALVTYSPVTEKFVAPAMSWGQLCEAAIGYSDNTAANLLAKKLGGP -EAVTRFFADLGDKVTRLDRFEPELNSAVPGDMRDTTTPLAVSETLQKLTLGTALTPASRA -QLLQWMRDDKVANALLRSVLPAGWSIADKTGAGEYGSRSIISVVSPENGKPLIIAIYITQ -TEATLAQSNAAIARIGKTIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Oleiagrimonas sp. C23AA TaxID=2719047 RepID=UPI001420A718 ----LHTRLAALEARHGGRLGVAMLDTGTGAQL-RYRADHRFMMCSTHKVLTVAAILARVD -RGTERLDRRVVYGRDVLLEYAPTTRAHVGPPMTIEALCQAAITLSDNTADNLLLAQLGGP -EAVTGFVRSLGDHITWLARTEPALNYAMPDDHRDTTTPDAMLADLKALLLGTALSPASRL -RLLGWMQACQTGTQMLRAGLAAHWRCGDKTGSGPANELNDVAIVHPPGAAPLLITSFYAE -SVASLEERHGVIADIGRLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Agreia sp. VKM Ac-2052 TaxID=123316 RepID=A0A1T4Y7Z1_9MICO -------AFAQLEQEFDARLGIYALDPDTRAEV-AYRADERFAYASTFKALAAGILLKTVS ---DDELDGLITYDAGDLLPNSPVTEANVDNGMTLRAVAEAAVRFSDNTAGNIMLEHLGGP -EGFTQALRELGDTTSSSDRIETELNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQS -QLIDWMTGNATGAELITAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR -PTEDADYDNALIARAAEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium TaxID=2006849 RepID=A0A2E5G0C5_9GAMM ----FLARMDALEARHGGRLGVSVRDTTGRLAV-SHRGDDRFLLCSTVKLPLAALILSRVD -AGHESLERPIDYAEADLVTYSPETEQHVATGMTLGAICRAGLTQSDNTAANLMFDAVGGP -PALTDFIRSLGDTTTRSNRLETALNEPT-PDARDTTTPRAMRALMTKILLGDVLSPAARD -RLLSWMKANQTGDQRLRAGLPSAWPIGDKTGSGGNNTAADIAIAHPAPAHAIVISAYYAD -SSASRDARDQVLADVGRAVADLy ->[subseq from] UPI0012FE7EB9 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012FE7EB9 --sKLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=A0A5C8GYC9_STRLA -------ELADLERRYGARLGVYARNTRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTQENQATGMAMADVCAAAIQYSDNAAGNLLLRRLDGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALAASIERLALGRALAAADRE -RFVGWLKGNTTSGARFRAGLPKGWTIADKTGTGDYASANDMGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. CB02891 TaxID=2020329 RepID=A0A2M9L9T6_9ACTN ------DPFHQLEQRFGARLGVYVLDTGSGREI-THHADERFAFASTSKALAAGALLRRAS ---DADLEKVVTYRQADVLTWAPVTSKHVDTGMTLRDLLAASLDHSDNTAANLVTAEVGGP -AAVQQALRDLGDITTHVDRTEPTLNETAPGDTRDTSTPRALAADLRQYVLGDVLPADRRR -LLTDLMLANTTGGPYIRAGVPAGWKVADRTGNADHGTRNDIAVAWPGGGSPVVIVVLSDR -ARPDAASDDELIARATEAALN-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00047149EA ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DconLS TaxID=1839766 RepID=A0A1C5DRH0_9ACTN ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALTAPDRE -RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus M0605 TaxID=1449358 RepID=X7R747_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILDHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045A6AA7 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRDSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Root1310 TaxID=1736452 RepID=UPI00099ECFB7 ----VTDRLRDLEAGHGARLGVFAHNVRTGRSV-RYRADERFPVCSLFKTLAVAAVLRDLP ---EGTPDRRVFWTAADVVENSPVTQEHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP -AALTRFARSVGDRVTRLDRWEPELNSAEPDRITDTTSPYAIGRTYARLVLGDALAPADRR -RLTDWMLGTVTSANRFRAGLPPTWTLADKTGGGWYGANNDAGIAWTPDGTPVVLVVQLTK -PARDAAYDHELIVETAGLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas kerstersii TaxID=225992 RepID=UPI000985D27E ---SLQAHCQALEAKAQGRLGVSIVDTATGQQW-GWREDERFMMLSSFKLLASALVLHRVD -QGQESLQRRMAYPRSALIPWSPITEKHADGPLTLGELCAATITTSDNTAGNLILESYGGP -AALTAYARQLGDAVTRLDRNEPTLNRPSSDGLLDTTSPRAMAQTMHKLLVGGALSTASRQ -QLRQWLLANTTGGKRLKAGVPASWQVGDKTGTNAT-DANDIGFLIPPQGAPWIVTAYLAG -SSAEGAVKDACLADVAAWVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E82328 ---DLADRFAELERRYDARPGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001121DB32 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSALPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. B-9 TaxID=1055192 RepID=UPI0003FA474E ---QFAQAMQALERAVGGRLGVSALNTVTGAAL-GWRQNERFAMCSTFKMLLAAQVLSRVD -AGQDRLDATLTFDRSVLVEHSPVTEKFAGKAMTVEALCDAIMTISDNGAANLLLERVGGP -ASFTAYMRSLGDPTTRLDRIEPAMSESKPGDVGDTTSPLAMLSSMRALTLGKALSAANRE -RLVGWMQANTTGDHCLRAGAP-GWKVADKTGSGP-GTRNDIGLLWAPGATPILVTSYLTE -CKAEPKARDAALARVAAELVKLw ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011231127 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lavendulae subsp. lavendulae TaxID=58340 RepID=A0A2K8P756_STRLA ---DVLRQLRALEQEHSARLGVYARDTATGRTV-LHRAEERFPMCSVFKTLAVAAVLRDLD -RDGEFLATRLFYTEQEVKDFGPVTGENLAAGMTVERLCAAAICQSDNAAANLLLRELGGP -EAVTRFCRSVGDRTTRLDRWEPELNSAEPGRLTDTTTPRAIGRTYGELVLGDALAPRDRE -RLTGWLLANTTSTERFRKGLPADWTLGDKTGGGAYGTNNDAGVTWPPHRPPVVMVVLTTH -DRPDAVADNPLVAKTAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia TaxID=1822464 RepID=I5CW11_9BURK ----ARERFEKLEASSGGRLGVAALNMADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERSLLDERVRYGDADLVANSPVTKRRAGEGMTIGELCAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VTKQTLPRDEVVAEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium boenickei TaxID=146017 RepID=A0A2A7P2D7_9MYCO ----VDDQIADLERRHNALIGLYAANLDSGRTL-AHRSDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDREAIVPNSPITETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALASGYREVLAGDALSPPQRR -LLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAVMTRS -QADDADNLRPLIGELTAAV---- ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. TaxID=267 RepID=A0A2G1Z1T6_9RHOB --eTLAATVAQIESQFDSRVGIAIVDTGSNFTW-SHRDDERFLMNSTVKVPICGAVLARAD -VGSLSLSQDLPIRQSDLVDYAPVAERHVGGDMTIAELCLAAIDQSDNTAANLLIDHLGGP -QAVTGFFRDLGDPVSRLDRYEPALNSFAPGDPRDTTTPAAFAESLRRMLLGDALSPASRN -QLAEWMRHGGVTGKLLRRDAPAGWRILDKSGSGSH-NRNIVAVINPDDAAPWIVTIFLSD -MDADFATRDAALQRIGSDVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rayongensis TaxID=1429076 RepID=UPI001354B089 ---SVTARIDALERSYAGRIGAFALDTGTGRVV-AHRADERFAFASTFKAALAATVLHKAR -SDPGLLHRRLHWTADDLLPNSPVSEQHVADGLTAAELCRAAITQSDNTAANVLLKQVGGP -AGVTRYLRSLGDPVSRLDHTEPALNQWKPGQRQDTVTPAAIGRDLASVTVGRALPAPDRA -QLNAWLRATVTGDARIRAGVPKNWLVGDKTGTGSYGTANDIAVVTPPGHAPVIIAVYTNR -NDPKGSPDESVIARTATLLVE-- ->[subseq from] Beta-lactamase n=1 Tax=Embleya hyalina TaxID=516124 RepID=A0A401YM29_9ACTN -----TGRLRALERAHAARLGVFACDVHSGRTV-VHRADELFPMCSTFKTIAVAAVLRDLD -RDGEFLGRRIRYTEKDVTEYAPITGRNLADGMIVADLCAAAIAYSDNGAANLLLRRLGGP -GAVTGFCRSVGDGVTRLDRWEPALNSAEPGRVTDTSSPRALGRTYARLALGGALDARDRE -RLNGWLLANTTGGKRLRAGLPPDWVVADKTGTGDYGTTNDVGIVRPPGRGPIVMAVLATK -DDAAAPADEPLLAGTATVLAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_105 TaxID=1881019 RepID=A0A1H5FN79_9ACTN ------ARLRRLEREHTARLGVFARDLRTGRTV-AHRADERFPMASVFKTLAVAAVLRDLD -RDGEFLARRVHYTQAYVARISPVAGENVSGGMTVAELCDATIRFSDNTAGNLLLKELGGP -TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPHAIGLDYARLVLGDVLEPHDRA -RLTDWLLRNTTSTEKFRRGLPADWLLADKTGSPRYGGANDVGIAWRPDGTPIVLAVLTTQ -PEEDAPTDNPLVAGTASLLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sporolactobacillus terrae TaxID=269673 RepID=UPI0009DF7E4A ----TDQAFVQLEKKFDARIGVYAFDSGTQRTV-AYRPDDRFAYASTYKALAAGAVLQQSS ---IHQLNEVILFSKDDLVTYSPIAENRVNSGMTLGEICEAAIRYSANTAGNLLLKKLGGP -NGFEKTLNKIGDNVTKANRFETDLNETIPGDLRDTSTASALATDLKAFSVGKAPPTHKRK -MLADWMRGNTTGDQLIRAGVPKGWAVADKSGAGGYGTRNDLAIVWPPKRLPIILAILSSR -DTKDAPYHNELIAEAAKLTI--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_040 TaxID=2175625 RepID=A0A2W1V598_9MICO ---ATARAFAALERRDDVRLGVVAVDTGDGRTI-VHRAGERFAFASTIKVFIAAAVLDASS ---DADLATVVHYDRGDLLEYAPVTREHVDTGMTVRELVDAALRSSDNTAANLLVERLGGP -HAVERWLRGIGDRTTSVDRVEPDLNQAIPGDRRDTTTPERFAADLRTVLLGDALDAADRR -VLREAMLGNTTGDATIRAGVDPSWRVADKTGTASYGVRNDIAVVTPPGRDPVVLVVMTSR -ADPGAEPSDALVAAATRTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DE56F5 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNPTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis panacis TaxID=2340917 RepID=A0A419I939_9PSEU -------DFGALKHSFGARLGVYAVDTGSGREV-AYRADERFAYASTHKVFSAAAILKRDD -----DLNQVIKYQAGDLVTYSPITEKHVGTGMPLRDVLDAALRYSDNTAANLMFRQIGGP -AALGASLRGLGDITTHVDRTEPTLNEATPGDLRDTTTPRAWAADLRGCALGRGLTPDDQK -VLLDMMRANTTGATVIRAGVPAGWQVADKTGSAEYGGRNDIAVLWPPHRAPIVLVLLSSK -PAKDAKSEDKLLARATTEVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00031E7033 ---ETAAAFRKLERKYDARLGVHAVDTGTGREI-SFHAGERFAYASTHKAFTAAAILDKRS ---LSGLDKVITYRKEDLLPHSPVTREHVEEGMTLRALCAAALRQSDNAADNLLLRELGGP -KALDAFLEKLGDDVTNVNRYEPELNEAAPGDDRDTTTPRAWTADLRAVALGDGLNRKEQA -QLDDWMRNSPTGKTLIRAGVPEKWTVSDKSGGGRHATRSDIAVVRPPGGAPLVVTVMSRR -TERDAEYDDRLVADAASVVADE- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000C7D9FE2 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Agreia bicolorata TaxID=110935 RepID=UPI0005E8909F -------AFAQLEQEFDARLGIYALDPDTRAEV-AYRADERFAYASTFKALAAGILLKTVS ---DDELDGLITYDAGDLLPNSPVTEANVDNGMTLRAVAEAAVRFSDNTAGNIMLERLGGP -EGFTQALRELGDTTSSSDRIETELNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQS -QLIDWMTGNATGAELITAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR -PTEDADYDNALIARAAEAAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces zhaozhouensis TaxID=1300267 RepID=A0A286E5G1_9ACTN ---EAAAEFEALEGEFDARLGVYALDTGTGAEV-AHRDGERFAYASAFKALLVGAVLDEYG ---TAGVEEVVDYTEDELVDYSPVTENFVDSGMSLSQLSAATLWYSDNTAANLLLEAVGGP -AGLQEALREMGDDTTEVSRYEPELNEATPGDTRDTSTPRAMAEDLRALLLADALGERERH -LLRQWMETNTTGGTLVRAGLPAEWTVADKSGSAGYGGRNNIAVVWPDDGDPIVLAVLSSR -DEEDAERDDALIARAATAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium TaxID=379 RepID=UPI000645558D -----EAQLAALESKHPGRICVSVLDMASGKRI-EHRPGERILICSTFKTLAAALVLARVD -KGEEKFDRRVHYTERDLVDSSPATKANVGKGMTIAELCAAMMTLSDNTAGNLLLASFGGP -GALTTFCRSLGDEITHLDRLEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSPASRL -QLAAWLMTNRTGDTRLRAGLPKNWLAGDKTGTNGDGNANDIAVLWPSNRAPIIVTAYCEI -PAIAADERNAIIAEIGRIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111CBB16 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHf ->[subseq from] Beta-lactamase class A n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A3N1Q1E4_STEMA ----TAADFAALEKASGGRLGVTLLDTRTGKRA-GHRQDERFPMCSTIKWMIAAAALHRAE -RQPGFLDERLPMRSEDLIEHAPTTRRHVGKDLSVRDLCRTTMVTSDNPAANLLLRRLGGP -PALTAFLRSHDDAVTRSDRYEPELNRFTPGDPRDTTSPAASAASLQRFVLGDALQPASRQ -QLADWLIDNETGDATLRAGLGARWRVGDKTGSNGKDTRNDIGVLWPLGGSAWVLTAYLQG -ASVDSGQRDAVLARVAAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TLI_053 TaxID=1855352 RepID=A0A1H1ZNP1_9ACTN ---EVTDRLRALEQSHAARLGVFAHNLATGRTV-AHRADELFPMCSTFKTIAVAAVLRDLD -RDGTFLAERRHWTTTDVTEYAPITGENLEGGLTIEELCAAAIRYSDNAAANLLLRELGGP -EAVTRFCRSVGDRVTRLDRWEPALNSAEPDRITDTSSPRALTRTYTRLTLGSALTPAHRR -RLTTWLLTNTTGTDRLRAGLPSTWTTAEKTGTGNYGTTNDAGVTRPPTGGPIVLTVLSTQ -HIAAAPADEPLVAEAARLVA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066A06A2 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011225645 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAEISQLILEHy ->[subseq from] Beta-lactamase class A n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=A0A2Y8ZXA4_9MICO ------------AAESGVTLSVAVTDLADGATL-IAGEDERVKAASIIKLPLLATLMADVD -AGELDLDQTVTIPAGDIVGGSGTLKDQFPLDITVAELMELMVQVSDNTATNVLIDLAGGF -DAVNDYVEALGFEDLYLGRKMI--HPASPPLQENYISAEEVTELVTLLWEGEILSAESSE -HIIDLMRGQLV-DTKFGAVIP-RAHLANKTGELAD-VSHDSGIVLLPGRE-LAFTTTTSF -TDLPRAEADVFVQETARVVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=A0A2Y8ZXA4_9MICO --------------AQDVRVSVGFSDLADGDRV-LLGSQEPYNPASVIKLSLLAAVMRQTE -RDLLHLDAPVTISPYMVVGGSGSFQDEMPFTTTVRELVRRMVVESDNTATNVLLYHI-GL -PTTQELIDDLGLDVMRFNRQMFPG--ELIDEPANVLDVGDTLALLEAMYGDELLGEESRE -QILTWMSDQEV-DTKFGAVLN-DAPVAHKTGETGN-VTHDVGYFLVPGHE-AAVVVLTEV -TNETQEIGNPIVQEIGLAVYDY- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI001110B76F ---KLNEDLTAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITK -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA81_KLEPN ----------------VGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITVSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVV----- ------------------------ ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0003EA70BC ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=UPI000B7FA1FD ---TVTGRLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAILRRDR --DGSLLRKVITYTQSDVDKHAPVTGRNLANGMTVAALCEATITHSDNCAANLLLRELGGP -TAITRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNPNDSD -QLTNWLLANTTGGNRIRAGLPSAWRWGDKTGTGKYGTTNDAGIAFPPGRAPIVIAVLSTR -QDPTGGADEPLLAETAELVA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RQ02_9BACT ---TFQQTSANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RQ00_9BACT ---TFQQTSANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4S1MIU2_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRASLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TUMSAT_DE1_S1 TaxID=1441607 RepID=A0A0I9RJ70_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARINERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TLI_105 TaxID=1881019 RepID=UPI000B868114 ------ARLRRLEREHTARLGVFARDLRTGRTV-AHRADERFPMASVFKTLAVAAVLRDLD -RDGEFLARRVHYTQAYVARISPVAGENVSGGMTVAELCDATIRFSDNTAGNLLLKELGGP -TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPHAIGLDYARLVLGDVLEPHDRA -RLTDWLLRNTTSTEKFRRGLPADWLLADKTGSPRYGGANDVGIAWRPDGTPIVLAVLTTQ -PEEDAPTDNPLVAGTASLLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=UPI000B8762A3 --------LVELERRYDARLGLFARNAATGRTL-AHRADERAALCSTFKVYASAALLRAHG -LAGGYFDRVIRYDAGQLVEYSPITETRVGTGMTVGELCAAALQHSDNTAGNLLLRELGGP -RAITDFARSIGDPVTRLDRWETELNTAVPGDERDTSSPKALADGLQALLLGDVLGAPERD -LLTRWMLGNTTGDARIRAGVPGDWRTADKTGGGSYGVANDFAVTWTGTGTPIVISLLTGR -PRAEDAANNALLAEATRLVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces cacaoi subsp. cacaoi TaxID=66857 RepID=A0A4Y3R644_STRCI -----AAELKALEDEFDVRLGVYAVDTGSGREV-AYRDGERFPYNSTFKALECGAVLDKHT ---DREMDRVVKYSEDDLVDNSPVTEKHVEDGMTLTALCDAAVRYSDNTAANLLFETVGGP -KGLDKTLEGLGDHVTRMERVEPFLSRWEPGSKRDTSTPRAFAKDLRAYVLGDVLAEGDRK -QLTTWLRNNTTGDGLIRAGVPEGWVVGDKTGTGSYGARNDMAVVWRPDAAPLVLNVMVHG -HTKDAELDSELIARATEVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium casei TaxID=33889 RepID=UPI00119F6A92 ---EADSAFTQLEDDFDARVGVYAVDLDTGREL-AWRGDERFAYASTIKAMASAALLDEVG ---TDGLSKRVAISEDDIVSHSPVTETKVGGTMTLAELCEAAMTQSDNGAANLIFAELGGP -AALDERLNDLGDTGTTVSRTEPGLNEAKPGDPRDTTTPRASAGNLREYVFGGALEDDEAT -TLTDWMKATQTGDTLIRAELPEEWTVGDKSGTGYYGSRADLGIVWPGDGGPIIISVLSAK -DEKDAEADDRLISGAAAIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis decaplanina DSM 44594 TaxID=1284240 RepID=M2YBH8_9PSEU ------ADFERLERTFGARLGVYAVDTATGREV-AFRAEERFAYASTHKVFSAGGVLQRTP ---VADLDRTVTYGRKDVVADSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPALNDTAPGDNRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGLP-GWPVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR -PDKDAKIDNKLLAEATAAAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces qaidamensis TaxID=1783515 RepID=A0A143C3U9_9ACTN -------RLTDLERAYGARVGVYALATGTGATV-AHRAGERFAFCSTFKALAAAAVLHHRT ---LSGLDRRVTYTEADLRSTTPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -PKLTAYLRRLGDEVSRMDHYEPELHDVPPGDPADTTTPQAIATDFRRLLLGTALPARERR -LLMDWLSRNATGARRIRAGLPADWKVADKTGTGDYGRANDIAVVHPPRTEPLVLAVMTDR -PGRDAEPSDALIAEATRRAV--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000681511C ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000271BEE2 -----RGRFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VTKQTPPRDEVVAEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Methyloceanibacter stevinii TaxID=1774970 RepID=A0A1E3VPD2_9RHIZ ---DLASQFAKIEKKIGGRLGVAVS--GAGLKA-AYHGGERFPMCSTFKLLAVAAVLHRVD -EGDEMLSREIPVPPDAILDYAPVAKEHAGGTMTISELCEAAMVWSDNTAANLILESLGGP -EAATAYVRSLGDTVTRIDRMEPEANVFGPGELRDTTRPRAMLDDMQELFLGDALSPLSRD -RLTEWFVANQTGKDRLRAGLPPTWRVGNRTGTGPHGTSNDVAMAWGEDGQPILIAAFLTG -SKADAAARDNALADVGRAI---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045A767A ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKAIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0010553C4E ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPASTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBX8_STEMA ------ADFAALEKAIGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PAN_FS17 TaxID=1855351 RepID=A0A1H4SDP0_9ACTN ---ATTDRLRELERQHGSRLGVFAYNVRTRKTV-THRADELFPMCSVFKTLASAAVLRDLD -RDGEFLRRRIHYTEADLPEGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR -LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK -PAQDAAWDDALVAETAALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Luteimonas abyssi TaxID=1247514 RepID=UPI000737B0D1 ------DALADLERGAGGRLGVALLDTADGRRI-GWRDDERFPMCSTFKALLAGAVLHAVD -HGRADLHHALPVRADDVITHSPYVATRVADGATVADLCRATVTLSDNAAANLLLPLVGGP -AGLTAFLRGIGDPVTRLDRREPELNEAAAGDPRDTTSPRAIVDSLHALLFGDALRAPSRA -VLAGWLIDNRTGDARIRAGTPAGWAVGDKTGTCGSGTAADVAVLYPPERAPLLLAIYAHG -AAISGAPLDALQADIARR----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MUSC 14 TaxID=1354889 RepID=A0A1S2Q318_9ACTN -----EAELNELEQRHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --DCAPPDKLIHYPPHDILPHSPRTAEHVDTGMTVADVCAAAIRYSDNAAGNLLLREIGGP -AGLTRFFRSLGDEASRLDRWEPDLNGAVPGDLRDTTTAEALGGSFARLTLGRALAGADRA -RLVGWLKGNTTSGARFGAGLPRDWVLADKTGTGDYGTANDIGVAWTTRGTPLLLTVLSAG -TVQDAPADDALVAEAARILA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JCM 19046 TaxID=1460640 RepID=W7ZJT7_9BACI --dDLTAPFSELEDQYDARLGVYALNTGNGQTI-AFNEDERFAYASTHKALAVGVMLQQLS ---IEDLDKQVTFSEAELVTYSPITEQHVETGMSLREISDAQIRYSDNTAANLVFNEINGP -AGFKEALRAIGDDVTEPERMETELNDVNPGETRDTSTPKALAESLYAFSFGDALDKEKQT -LLNDWLIHNTTGDDVIRAGVPDDWVVGDKTGSASYGTRNDIGIIWPPNDEPIVIAVLSSK -DEQDGKSDDALIAEATEAAL--- ->[subseq from] BlaL family class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1868 TaxID=1463892 RepID=UPI0004C51F93 ---AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS -AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLGGP -KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE -QLNDWMSGNATGDALIRAGVPKDWKVADKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG -DTQDAEPHDELVAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium brisbanense TaxID=146020 RepID=A0A100VXX9_9MYCO ----LDDQIAGLEKRNNASIGVFAANVDSNRTV-AHRADETFAMCSTFKGYAAGRVLQQVD -RGQLALDTRIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKLIDGP -PGITAFARSIGDNRTRLDRWETALNSAIPGDLRDTSTPAALGAGYRAMLTGDVLSPPQRQ -QLEEWMRGNET--SSMRAGLPAGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -RADDAANLRPLIGELTALVV--- ->[subseq from] AXC family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009E9AA71 ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADELFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI0009E340F3 ---QLAETVAKTESRLNARVGVVLYDTGSGWSW-TNRADERFLMNSTIKTPICGAILSAAD -AGTLTLDEELPVLQSDIVSYAPVTEKKVGQSMPLSELCLATIDMSDNTAANLLINRLGGT -AAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLGDVLSPQSRN -QLTEWMSHGGVTGALLRKTAPEGWYIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD -VKADFATRNGALQDISAAVID-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Amycolatopsis TaxID=2618356 RepID=UPI00106EDEB5 -----QPDFAALEKAFGARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLTRTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLEDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYGTRNDIAVLWPPHRAPIVLTVLSDR -PQKDAKTDDKLIAQAAAAVVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE55_ECOLX ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardiaceae bacterium TaxID=1873463 RepID=A0A431NNZ7_9PSEU -------RVDDLESRFGARLGVWARDTGSGAEV-AHRADERFAFCSTFKMLAAAAVLRDVA ---PDRLDAVVRYSAADLMTSGRVTRDHVATGMTLRELCDAAVRFSDGTAGNLLMREVGGP -AGLTAFARSIGDEVTRVDRTEPELAQGAPGEERDTSSPRALGQDMQRIVLGDVLATDRRD -FLADPLVRNTTGDARVRAGVPAGRRVADKTGTGGYGTANDVAVVWPPGRAPIVVALMSTM -AQRYADVDEALLAEAAGRVMTAf ->[subseq from] Beta-lactamase n=1 Tax=Hephaestia caeni TaxID=645617 RepID=A0A397P7U0_9SPHN -------DLAAIATRSGGRLGVAALDTGSGRRI-GHDQDARYALCSTFKAPLAAAILARVD -AGDIALDDRLTFTDADVLDYAPVVKAHRAGHLTVGEACAGAVELSDNSAANLLLKRIGGP -AGLTRFMRAAGDSVSRLDRYETALNLVGPGEIHDTTTPAAMIGLLGALALGEVLSPSSRA -QLIAWLVAGQTGGALLRAGLPPGWRVGDKTGRSGEGAVNDIAIAWPPRRAPILIASYLYA -PDLSADRANAVHADVARAVAAAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075743DF ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVVGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Agreia sp. VKM Ac-2052 TaxID=123316 RepID=UPI000999A0AB -------AFAQLEQEFDARLGIYALDPDTRAEV-AYRADERFAYASTFKALAAGILLKTVS ---DDELDGLITYDAGDLLPNSPVTEANVDNGMTLRAVAEAAVRFSDNTAGNIMLEHLGGP -EGFTQALRELGDTTSSSDRIETELNSAIPGDTRDTTTPRAFALDLATLLTTDALGAAQQS -QLIDWMTGNATGAELITAGLDAGWSVADKSGAGAYGTRNDIALLWPPSGSPIVLVVMSNR -PTEDADYDNALIARAAEAAL--- ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. SID9913 TaxID=2706117 RepID=A0A6B3DHJ7_9ACTN ----LSGRFRALEKRYGARLGVYAHDPRSGRTV-RYRADTLFPQCSLFKTLAAAAVLRDLD -RDGEVLARRIRYTEADLVEGSDHTRENLATGMTVAALCDVAIRFSDNTAANLLLRELGGP -TAITRFARSTGDRVTRLDRWETELNSAEPWRTTDTTSPSAIGRTYARLVLGDALNRCDRS -RLTDWLLRNETSGTRLRAGLPGTWTVADKTGGGPYGTNNNVGIAWTDDGSPLVLSLLSRM -SERDAVKNDALIAGAAAVLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Phyllobacteriaceae bacterium SYSU D60010 TaxID=2267839 RepID=UPI000E651252 --qDAAAKLAALEGRHAGRLCVSILDLASGKRV-EHRAHERILMCSTFKALAAALVLSRVD -KGEEKLDRRITFAKKDILPASSVTQAHVGEPMTMAELCEATVTRSDNTAGNLILASFGGP -AGLTEFFRKLGDDVSRLDRIETELNYDGPDDVRDTTTANAMLENLRKLLFTDFLSGPSRS -QLAAWLIATKTGDSRLRAGVPKTWLVGDKTGTNGYGNANDIAVLWPPDRSPLIVTAYCEI -PAIPADERNAVIAEIGRIAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia SKK35 TaxID=1118156 RepID=M5CMQ1_STEMA ------ADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -PALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QLADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces dioscori TaxID=2109333 RepID=A0A2P8PXG6_9ACTN ----TVRALAELERTHNARLGVYAHNTATGKTV-RYRADETFPMCSVFKTLTAAAVLRDLD -RRGEFLDLLIRYTEQDLKDGSPVTGRNLAGGMTVAALCHAAMAHSDNAAANLLLRELGGP -TAITRFCRSIGDPTTRLDRWEPALNSAEPWRTTDITSPAAAGRTYAKLALGDALVPRDRR -QLTEWLLANTTSTNRFRKGLPADWALGDKTGTGKYGTTNDVGIAWTPAGAPVVLSVLSTK -PDPDALMDEPLVARAAELLA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00112146AA ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARNQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Neisseriaceae bacterium DSM 100970 TaxID=2052837 RepID=A0A2I7N7M1_9NEIS -----YQQMSKLESTVGGRIGIAVYNTRNKETL-SYRGNERFPFCSTGKVMTVAAILKASE -KESDLLTKIIKYNKADTDKYAPITSKYVAKGMTISELSQAALDYSDNTAMNLLVAEAGGV -GKITDYARSIGDEKFRLDRMEPELNTAIPADNRDTTTPLAMTMSLDKLAFGQSLESNSQA -YLTKWLKANTTGDKRIRAGVPNSWIIGDKTGTGAYGTTNDIGIIWAAKCDPIVISIYYTQ -DQKDAKSNDSVIASATKVAID-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A3E1IK87_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides zeae TaxID=1457234 RepID=UPI0013BE2D9D ---AAAARFAALERQYDARLGVVALEVDTGRVV-AHRPDERFAFASTVKALQVGALLRTAT ---EADLDRTVRWTEDDLVTYSPVTEQHVADGLTVRELADAAVRYSDNTAANLLFDELGGP -AGLTAELRRIGDTTTTSVREEPDLNTAVPGDVRDTSTPRALARSLASYTLGCVLAPDRRA -ELVDLLVRNTTGDALVRAGAPDGWTVGDKTGSAAYGTRNDIAVAWPPNRSPVVIAVLTSG -DEADDPTHDALVADATRVTF--- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238ZQF1_9ACTN -------RFAALERRHGARLGVYATATGTGAEV-AYRADERFAFCSTFKALAAAAVLHGNP ---LGHLDERVTYTRADVNSISPITKDRVDTGMTIRELCEAAVRHSDGTAGNLLMRDAGGP -ARLTAYLRGLGDTVSRMDDYEPELNRIRPGDPRDTTTPRAIAADYRAIVLGDALEPAKRA -LVRGWLERSATGAERVKAGLPEGWRTASKTGTGDYGRANDIAVVWPPRGAPLMVAVMSDR -PGYDTPPKNALIAQATELVVS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Methylobacterium mesophilicum SR1.6/6 TaxID=908290 RepID=A0A6B9FGR3_9RHIZ ------SDLAAIEHRLGGRLGVAAYS-AERALL-RHRADERFPLCSTFKVLAVAAILARVD -AGSESLDRTVRYGAQDLLSYAPVTRKALEAALSVSDLCAAALEWSDNTAVNLLLVPLGGP -AGQTAWLRGLGDPVTRLDRTEPTLNEAIPGDSRDTTTPEAMQATLGRILLGSVLSPSSRA -RLEGWMVASQTGFKRLRAGLPKDWPVGDKTGSGDNGSFNDVAILRPPGRAPVIAAVYMTG -ATAPAKVVESAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F1A10 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -AGADAAPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID8111 TaxID=2706100 RepID=A0A6B3ANJ4_9ACTN ----LSGRFRALEKRYGARLGVYAHDPRSGRTV-RYRADTLFPQCSLFKTLAAAAVLRDLD -RDGEVLARRIRYTEADLVEGSDHTRENLATGMTVAALCDVAIRFSDNTAANLLLRELGGP -TAITRFARSTGDRVTRLDRWETELNSAEPWRTTDTTSPSAIGRTYARLVLGDALNRCDRS -RLTDWLLRNETSATRLRAGLPGTWTVADKTGGGPYGTNNNVGIAWTDDGSPLVLSLLSRM -SERDAVKNDALIAGAAAVLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DFD63B ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVVHQKP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2L1J0Y0_PSEAI -----------------------EMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106CSX4_9BURK ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4Q6ZL72_KLEPN -----------------------------------------FEMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F5611 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Curvibacter delicatus TaxID=80879 RepID=UPI00082985EA -----ALALQALEARSGGRLGVAIRDTGSGAQL-LHRADELFPLCSTFKLLLAAYVLHLVE -QGAEGLERRVVYPASALVAHSPRTAPRTGDGMTVAQLCEATLVISDNTAANLLLARHGGP -QALTAWLRGLGDTQTRLDRWETDLNSALPDDPRDTTTPGAMLETMDKVLLGSVLGPVSRR -QLQTWIRGNLTGDHALRAGFPSGWVVGDKTGSGDRGTRNDVAIAWPAERAPLLVASYLTG -AQITPAQRDGVHAEVARLA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4R5BKT8_9PSEU ---------AELERRYDARLGLFARNVATGRTV-AHRADERVALCSTFKVYASAALLRAHG -LAGGYFDRVIRYDAGQLVKNSPITETRVGTGMTVGELCAAAVQHSDNTAANLMLRELGGP -QAITEFARAIGDPMTRLDRWEVELNTAIPGDERDTSTPRALGDGLQRLLLGDVLGPAERD -RLTGWMLGSATGAARIRAGVPSSWRTADKTGGGSYGVANDIAVTWTDTGAPIVISLLTGR -PREHDTANNALLADAARLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas daejeonensis TaxID=659018 RepID=A0A0R0EDG7_9GAMM -----TDDFAALEKRSGGRLGICLWHPASGARF-GHRMDERFPMCSTFKFLLAAAVLHRAG -RGELSLDRRVPVRAADILHHSPASTRHVGKDMSVRDLCRATLTISDNAAANLLLPLIGGP -AGLTAFLRAQGDALTLCARHEPELNLFAPGDPRDTTSPAAMAGNLQRFVLGDALEPASRM -QLADWLIDNQTGDARLRAGLPRGWRVGDKTGSGYDGITNDIAVLWPEQGAPWLLACYLQG -STLGDDDRNGILRRVGELAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces curacoi TaxID=146536 RepID=A0A117P5D1_9ACTN ---SATAEFRSLEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG ---TDGMDRVVRYSRDDLVADSPVSENFVKTGMSLRGLCAATLWYSDNTAVNLLLDELGGP -DGLEKVLEEFGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRTFLLGDALKADERE -LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVMSSR -DKQGAERNDALLAKAATVAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium simiae TaxID=1784 RepID=A0A5B1BKM7_MYCSI ---DLSGRFEPLERQYDARLGVYVPAASPSAAI-AYRADERFAFCSTFKAPLVAAVLHQYP ---LTHLDKVITYSSDDIRSTSPVTQQHVQGGMTIGQLCDAAIRYSDGTAANLLLADIGGP -AAFTEYLRSLGDQVSRLDQEEPELNRDAPSDERDTTTPHAIALVFQQLVLGDALAPDKRA -MLIDWMARSTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPTGVPHVVAIMSDR -AAYDALPNEALIADAAKYIAD-- ->[subseq from] Uncharacterized protein n=1 Tax=Achromobacter sp. RTa TaxID=1532557 RepID=A0A095VUS7_9BURK ---ALNQALAQLEASSRGRLGVALLDTASGQTA-GYRADERFLMLSSFKTLAAAYILARAD -RGEDRLDRRIPITQADLQEHAPVTRLHVGPQMTLAGLCEATITTSDNTAANLMHRSYGGP -QALTRFIRSLGDTVTRHDRYEPELNRLHAGEPLDTTSPRAMTGTLDTLLFGQALKPQSRQ -LLQSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGSNDAGFAQAPGGAPIVVSAYLET -TGIPMPERDRIIAEVGGLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium nanningense TaxID=1325118 RepID=A0A4Q0RUT1_9BRAD -------EFESYERESGGRIGVYAENLATGKKL-AWRADERFVMCSTFKASLAACVLARID -RGEEQPTAMIPYGKDDLLEYAPAAKQNLAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTTFWRSIGDSASRLDHNEPELNRSPPGNPQDTTTPMAMAGNLRRLVVGEALSPASRA -LLRDWMENCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVVWPKPETPILIAAYTQG -GTPKPAQIEAAFARIGRMAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=UPI0011958D9B -----DDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -PGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSSPAALAAGYRQVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDADNLRPLIGELTAAV---- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011205D71 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Xanthomonas retroflexus TaxID=305959 RepID=UPI000B448320 ----AAADFAALEKACSGRLGVTLLDSAGGRRF-GHRQDERFPLCSTFKSVLAATVLKQAE -RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFDQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. SKA14 TaxID=391601 RepID=B8L6C1_9GAMM ------ADFAALEKASGGRLGVNVLDTGSGRSIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEQDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHSGPAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase AXC-5 n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5C0PY34_ALCXX ---AFQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADELFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVRGYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIAAYLET -TAVPMEERDRCIAEVGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A088DJ21_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLTGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E4E356 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLPQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011238C17 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S054 TaxID=1394599 RepID=A0A0I9QQQ6_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A088DK81_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A072F0N7_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D0F98 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011220718 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0009579BE0 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces globosus TaxID=68209 RepID=A0A344U1U5_9ACTN -------ALRALEREYGARLGVYAWDTATGRTA-AYGADALFPQCSLFKTLAAAAVMRRFD -RDGEYLAKRIHYTQADVTRGGEITEENIAAGLTVAELCSAAIAHSDNTAGNLLLEELGGP -TAITSFCRSLGDPVTRLDRWEPELNSAEPWVSTDTTSPRAIARTYARLVLGDALRPRHRE -LLTGWLLGNTTSRDRLRAGLPADWAVADKTGAGSYAVNNNVGIAWPPGRPPVVIAVLSTK -PEAAAQREDSLVARAAGLAVR-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MYb57 TaxID=1827305 RepID=UPI000CF72804 -----AADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI001110F374 ---KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMINTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Class A beta-lactamase n=2 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A4U6NVG0_9MYCO ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPSLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00027FCDEB ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEAPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758097D ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0013DCDFB8 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. QMT-12 TaxID=2717324 RepID=UPI00141554BF -htALTRRLRNLERERSARLGVFAQDMATGRTV-VHRGHELFPVCSVFKTLAVAAVLRDLD -TDGTYLSRRIRYTKQDVVRHAPITGENLARGMTVEALCAATITHSDNTAANLLLAKLGGP -SSVTRFCRSVGDFVTRLDRWEPDLNSAEPDRTTDTTSPYAVGRTNARLILGDALDPADRD -RLAGWLLANTTGGKRLRAGVPGDWSVAEKTGTGAYGTTNDVGVAWRPGRGSVVLSVLSTT -QDPDAPADDELIARAAALIAA-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium lacus TaxID=169765 RepID=A0A1X1YXR3_9MYCO --qDLAARFAELEQKHQARLGVYVPATGPTAEI-AYRADERFAFCSTFKAPLVAAVLHRGP ---LTRLDRVITYTSDDIRSTSPVTQQHVQDGMTIKQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDAVGRLDQEEPELNRDPPGDERDTTTPHAIALVYQQLVLGDALNTDKRA -MLTDWMARSTTGAKRIRAGFPADWRVVDKTGSGDYGRANDVAVVWSPSGDAHVVAVMSDR -VAYDAEPSDALVAAAATCVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MUSC 14 TaxID=1354889 RepID=UPI0009A1077F -----EAELNELEQRHGARLGVFARNLRTGRTV-SHRAGERFAMCSTFKAFAAAAVLRDHG --DCAPPDKLIHYPPHDILPHSPRTAEHVDTGMTVADVCAAAIRYSDNAAGNLLLREIGGP -AGLTRFFRSLGDEASRLDRWEPDLNGAVPGDLRDTTTAEALGGSFARLTLGRALAGADRA -RLVGWLKGNTTSGARFGAGLPRDWVLADKTGTGDYGTANDIGVAWTTRGTPLLLTVLSAG -TVQDAPADDALVAEAARILA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis indica TaxID=436663 RepID=A0A239DI11_9SPHN ----IARKLAALERQAGGRLGVCFRDAASGRSA-GHRVDERFAMCSTFKWPLSAVVLKAVD -DGKLALDRRVPYGKADLIPNSPVTSKRVGEGLTVAELMEATITTSDNAAANLLLPLVGGP -EAVTRQFRAWGDPVTRLDRTEPALNSVAPGDVRDTTTPGAMAALLDTILLGDVLSPASRT -RLVDWGVATTTGTRRLRAGIPADWRFGHKTGTATMNKYNDIAIAFPPQGAPLLITAYYEG -PVASRAEDEAVLASVARLAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. BK227 TaxID=2512162 RepID=UPI001046BA30 ----AEPDWAAIERRLGGRLGIAAASVD--RVLaAYRADARFPMCSTFKALAVAAVLARVD -VGRETLDRVVSYGLGDLLSYAPVTRKALEAGMRVADLCAATLIWSDNTAANLLLADLGGP -EVLTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPDSRA -RLEAWMVACETGRKRLRAGLPPDWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] Beta-lactamase 3 n=2 Tax=Bacillus sp. THAF10 TaxID=2587848 RepID=A0A5P9HT78_9BACI -----KIYFKELEKEYDAKLGVYALDTGSNRKV-SYRADERFAYASTHKVLAVGVLLMNRT ---IDELNETIKYTKEDLVNYNPVTEKHVENGMTLKELSDASIRYSDNTAGNLILEAIGGP -KGFKESLRKMGDHVTEPERMEPDLNDVKPGETRDTSSPKALAESLQAFTLGSVLPETKRN -LLIDWLKRNTTGDNLIRAGVPKGWTVGDKTGGAN-GIRNDIAILWLPDGAPIILVVLSSH -EKANSENVDELIAKATEEAVK-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001121499D ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TNLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1072 TaxID=1637871 RepID=UPI00075CA083 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSSDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PEAAAAARADVVAAAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0003BB5517 ----LADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKAIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0002ADF6EB ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLRDMD -DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase class A n=1 Tax=Fulvimarina pelagi HTCC2506 TaxID=314231 RepID=Q0G4Z1_9RHIZ --------AAKLEDRLETRVGVFVLDTGTGETW-EHRADERFPMASTFKSFACSALLDKAA -KGSLALDDTVAVEVSDLVTYSPVTEKRVGSRLSLREACEATLRTSDNTAANIVLEALGGP -QAVTDFMRSIGDDATRLDRYETALNEARPGDARDTTTPRAAAESLRTLLLDDGLGASDRQ -LLGNWMRSNEVAGPLLRAGIPDTWIAADRSGAGGFGTRGVTAVLWPPEHAPFVVAAYLTG -REIPMESRNEALAEIGRAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00119E5BA7 ------GELADLERRYGARLGVYARNVRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMADVCAAAIQYSDNAAGNLLLRRMGGP -GGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALATSIERLALGRALAAPDRE -RFVGWLKGNTTSGARFRAGLPAGWTIADKTGTGDYASANDLGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. Ec3.3 TaxID=189753 RepID=UPI0004030330 -------ALETYERESGGRVGFYAENLSSGKKL-GWRADERFVMCSTFKASLAACVLARVD -RGEDQLSAMIGYGRDDLLDYAPVARENLSKGMSVADMCKASVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPSAMAGNFRRLVLGEALSAASRA -QLTEWMVNCKTGAKRLRAGLPGTWRIGDKTGNNGKDASGDIVVAWPKPDTPILIAAYTQG -GTPNAAQIDTVFASIGKTVAA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=A0A1I6REP1_9PSEU --------LVELERRYDARLGLFARNAATGRTL-AHRADERAALCSTFKVYASAALLRAHG -LAGGYFDRVIRYDAGQLVEYSPITETRVGTGMTVGELCAAALQHSDNTAGNLLLRELGGP -RAITDFARSIGDPVTRLDRWETELNTAVPGDERDTSSPKALADGLQALLLGDVLGAPERD -LLTRWMLGNTTGDARIRAGVPGDWRTADKTGGGSYGVANDFAVTWTGTGTPIVISLLTGR -PRAEDAANNALLAEATRLVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758BFC1 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bradyrhizobium betae TaxID=244734 RepID=A0A5P6P4P5_9BRAD -------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLDYAPVAKQNLATGMSVAEMCKAIVELSDNSCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSQPGDPRDTTTPAAMAGNLRRLVTGEALSPSSRA -QLTEWMVGCKTGANRLRGGLPASWTIGDKTGNNGKDASVDIAVAWPKPAAPILIAAYTQG -GTPTAAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces afghaniensis 772 TaxID=1283301 RepID=S4MYE4_9ACTN -------RLADLEREYGARVGVYALATGTGATA-VHRADERFAFCSVFKALAAAAVLHHRS ---LGGLDRRVTYTRADLKSTAPVTGRHVATGMTLRELCDAAVRYSDGTAGNLLMRDLGGP -AKLTAYLRGLGDTVSRMDHYEPELHDVRPKDPSDTTTPRAVAADFRELLLGTALPAGERA -LLTDWLSHNATGARRIRAGLPKGWQVADKTGTGNYGRANDIAIVRPPRTAPLVLAVMTDR -PGYDAEPSNALIAEATART---- ->[subseq from] Class A beta-lactamase n=3 Tax=Burkholderia TaxID=32008 RepID=A0A118G180_9BURK ---AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001121E573 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. ZJ1307 TaxID=2685870 RepID=UPI00140E3646 ---------VALEERYDARLGIFAIDTHTGETV-EHRADERFAYASTYKALAAAALLARTG ---ERRWEEVVAYDADDLVTYSPVTEQHVGTGLSLQRIAEAAVRESDNTAGNLLLDELGGP -AGFQQALRELGDDVTVAARRETALNDTAPGDRRDTSTPRALAQVLQRYAVGDALRRPARR -TLLSWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRAPVVMAVFSDR -GTPDAEYDDALVAEAARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium casei TaxID=33889 RepID=A0A449DBP2_9MICO ---EADSAFTQLEDDFDARVGVYAVDLDTGREL-AWRGDERFAYASTIKALASAALLDEVG ---TDGLSKRVAISEDDIVSHSPVTETKVGGTMTLAELCEAAMTQSDNGAANLIFTELGGP -AALDERLNDLGDTGTTVSRTEPGLNEAKPGDPRDTTTPRASAGNLREYVFGGALEDDEAT -TLTDWMKATQTGDTLIRAELPEEWTVGDKSGTGYYGSRADLGIVWPGDGGPIIISVLSAK -DEKDAEADDRLISGAAAIAVE-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI0003A99C96 ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTATNIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S020 TaxID=1394567 RepID=A0A0I9QPR9_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLTGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Patulibacter americanus TaxID=588672 RepID=UPI0003B5356F ---QARPAFARLEREHTARLGVIATDTGTGRTV-SYRAGERFAFASTSKALTAGLLLQRAS ---DRDLRRVVRYRPSDLLEYAPVTRRHVATGMTLRGLTIAALQHSDNTAANLVMRELGGP -RGVERGLRALGDRTTEVERTEPTLNTAIPGERRDTTTPRAIARDLRSFVLGTALTPPRRA -LLARWMVGNTTGGKYVRAGVPAGWVVADKTGSAGYGTRNDIAVVWPPQGRPIVVAVLSDR -RRPSRASDDALIARATRTAVR-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111FE2AB ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNVLSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8GN88_STEMA ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas indicatrix TaxID=2045451 RepID=UPI000C19BDE0 ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia hospita TaxID=169430 RepID=UPI000DEFD2AA -----RGRFEKLEASSGGRLGVAALNTADGSYV-SYRESERFPMCSTFKLLVVALVLKRSM -AERSLLDERVRYGDADLVANSPVTKRRAGEGMTIGELCAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNGSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNATGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKQTLPRDEVVAEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=BLAC_STRLA ---DVLRQLRALEQEHSARLGVYARDTATGRTV-LHRAEERFPMCSVFKTLAVAAVLRDLD -RDGEFLATRLFYTEQEVKDFGPVTGENLAAGMTVERLCAAAICQSDNAAANLLLRELGGP -EAVTRFCRSVGDRTTRLDRWEPELNSAEPGRLTDTTTPRAIGATYGELVLGDALAPRDRE -RLTGWLLANTTSTERFRKGLPADWTLGDKTGGGAYGTNNDAGVTWPPHRPPVVMVVLTTH -DRPDAVADNPLVAKTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. S1 TaxID=718288 RepID=UPI000EF7A4CC ----HRREFRALESAFDARLGVYAIDTGTGREI-AYRDRERFPYASTFKALAAGAVLRE-- -EGLGGMERVVRYTKEELVEPSPVTEKHVGTGMTLDALADAAVRYCDNTAGNLLFEELGGP -KGLQAVLRSLGDGVTRMDRIEPELGDWKPGEVRDTSSPRALAGDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SGREAEPDNRLIARAASVVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Haloactinospora alba TaxID=405555 RepID=A0A543N9E8_9ACTN ----HEEEFRQLEEEFDARLGVYAVDTGSDREL-AHRAGERFAYTSLFKPLACGALMERRS --LSELKEEVVTYGADDLVEYSPVTKENVDDGMTLMEVCDAAMRYSDNTAGNLLFEEFGGP -EGLQEALEGIGDDTTRMERLETELNEAVPGETRDTSTPEAMTANLREYTLGDTLNEDERD -VLSEKMRNNTTGDDLIRSGVPDGWEVGDKSGAGGYGTRNDIGLLWPPEGDPIVLAVMSSK -DEEDAEYDDALVAEAAGVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis alba (strain ATCC BAA-2165 / BE74) TaxID=1205910 RepID=J7L1V5_NOCAA ---DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS ---LEEMERVITYDEDALVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP -EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE -VLVDMLVRNMTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM -EVEDAEPQDSLIAEATEVVVE-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D561E ---KLNENISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium miluonense TaxID=411945 RepID=UPI001199A454 -----EERLAALESKHPGRICVSILDMASGRRI-EHRAGEHILMCSTFKALAAALVLARVD -KGEEKLDRRIRYSEGDIIGGSPATKLRVGDGMTVAELCAAAVTLSDNAAANLLLASFGGP -KALTAFCGSLGDDLTRLDRTEPTLNYDTPDDQRDTTTAAAMLENLRRLLFTDVLTASSRS -QLAAWLITNKTGDARLRAGVPKDWLVGDKTGTNGAGNANDIAVLWTSKRAPIIVTAYCEI -PSISADERNAVIAEIGRIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000D7364EF ---KLNENISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=A0A1H0PDJ5_9PSEU ---TVTGRLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAILRRDR --DGSLLRKVITYTQSDVDKHAPVTGRNLANGMTVAALCEATITHSDNCAANLLLRELGGP -TAITRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNPNDSD -QLTNWLLANTTGGNRIRAGLPSAWRWGDKTGTGKYGTTNDAGIAFPPGRAPIVIAVLSTR -QDPTGGADEPLLAETAELVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DF8F2E ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRVDERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium wuzhouense TaxID=1986026 RepID=UPI000D9D283C -----TAAARQVESRLGARLGLMVVDTETNRQW-QYRSGERFAMASTFKALACAALLD--- -AGTQLLSRDIKIEAKDLLAHAPVTSKRVGTRMTAGDLCAATLSTSDNTAANLVLSTLGGP -KRVNAFLRSIGDTVTRLDRMEPALNEATPGDPRDTTTPEAMARTIGELLIGDGLAPLARR -QLTRWMEANAVADGLLRAGVPRDWRIADRTGAGGHGTRGIVAVMWPPGKKPVVAAIYLTE -TEASLATRDAAIAELGRVLA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011224F9F ---KLNEHISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARNQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B268A ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-3213 TaxID=1463846 RepID=UPI0005650416 -----QPDFAALEKAFGARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLARTVTIRQSDLVPNSPITEKHIGEQMSLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAELRRLEDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGSADYGTRNDIAVLWPPHRAPIVLTVLSDR -PQKDAKTDDKLIAQAAAAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A6BA4D ------DELASLEKEFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S024 TaxID=1394571 RepID=A0A0I9QQR1_VIBPH ---KLNEDISIIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A418LAY6_9MYCO ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPKQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis decaplanina TaxID=208441 RepID=UPI000A005A30 ------ADFERLERTFGARLGVYAVDTATGREV-AFRAEERFAYASTHKVFSAGGVLQRTP ---VADLDRTVTYGRKDVVADSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPALNDTAPGDNRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGLP-GWPVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR -PDKDAKIDNKLLAEATAAAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. CB00851 TaxID=1835005 RepID=A0A1Q4XLJ1_9PSEU ------DHLVELERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVLHRHP ---LSHLDTVVTYTEADLMASSAITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYLRALGDTVTRADRFEPHITTAVPGDPRDTTTPRAIGTDYRRIVLGDVLPPDQRA -FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDTAPLVVSIMSSK -AAADAGYDQALLAEAAAYVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI000F628191 -----HRRLSELEREYGARLGVYALATGTGATV-VHRADERFAFCSAFKGLAAAAVLHGNP ---LSHLDTVVTYTEDDLMKHSPITGKHVSTGMSIRRLCDAAVRYSDGTAGNLLLRDLGGP -GKLTAFARGLGDPVTRMDRTEPAITQATPGDPRDTTSPRAFGTDYRKLVLGTVLPADKRE -FLRDLLVRNATGAQRIRAGVPKDWVVADKTGTGDYGTLNDIAVAWPTGSPPLVISIMSSK -PAKDAAYDQRLLARAAEYVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S146 TaxID=1394680 RepID=A0A0I9QQ17_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHSLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila subsp. keratiniphila TaxID=227715 RepID=A0A1W2M0D0_9PSEU ------ADFEQLERTYRARVGVYAVDTATGREV-TFRADERFAYASTHKVFSAGGVLQRTP ---IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -PDKDAEIDNKLLADATAAAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCSS17_008 TaxID=2175647 RepID=A0A2W2A8K8_9MICO ---ATAREYAALEQRYDARVGVVAIDTADGRAV-GYRSEERFAFASTNKAFIAAAVLDASS ---ADDLDEVVRYDRGDLLEYAPVTRRHVDEGMTLRALVDAAVRESDNTAANLLVERLGGV -DGVTRWLRGIGDDVTRVDRVEPDLNTATPGDPRDTTTPAQSSADLRAVLLGDALDPDDRA -LLRSAMTGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVLRQPGRDPVVLVVFTAQ -DREDAEPSDALVAAATRVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SUK 48 TaxID=2582831 RepID=UPI00129BDA56 -------ELADLERRYGARLGVYARNTRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTQENQATGMAMADVCAAAIQYSDNAAGNLLLRQLDGP -AGLTRFFRSLGDDVSRLDRWEPELNTAIPGDPRDTTSPEALAASIERLALGRALAAADRE -RFVGWLKGNTTSGARFRAGLPEGWSIADKTGTGDYASANDVAVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007597147 ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNETAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007544EB4 ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium canum TaxID=324952 RepID=A0A1I4DEW3_9ACTN ---RARKELRTLEASFKGRIGAYAVDTATGKTV-TYRSGERFPLLSTFKAIAAAAVLHKAR -TDPGLLNKVVHWTSAELQEHSPGTEKHVQDGLTVARLCEAAITRSDNTAANMLLKQIGGP -AGLTAYFHTLKDPVSRLDRWETELNNWSPKEKRDTTTPASMGRDLRAVTTGDALDAKDRE -RLNAWLIANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDVAVVWPGKSAPIIMSIYTNR -RAADAPADDKVIADTAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) TaxID=83332 RepID=UPI00073339E9 ----LADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVATGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELARDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S141 TaxID=1394675 RepID=A0A0I9QQQ8_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNKIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754E4C2 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDMLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00066EFFC0 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=UPI0007EA6CED ----VDDQIAELERRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RGQISLDNRVFVDPEALVPNSPVTETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYREILVGDALSPPQRR -QLQDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDPKADNPLIGELT------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 05379 TaxID=2203207 RepID=A0A429GYR9_9ACTN ---ATTDRLRLLEQQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD -RDGEFLRRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR -LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK -PAQDAAWDDALVAETAALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092942F9 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEIQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=A0A3G2Q5L6_9VIBR ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A0C1Z8C8_9VIBR ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI00104B1DAC ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. MOS002 TaxID=2133947 RepID=A0A2T2QU87_9BRAD ---DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDQLAAMVPYGKADLLEYAPVARQNIAVGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPHDTTTPAAMAGNLRRLLTGEALSSTSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAAAWPKDAAPILIAAYTQG -GTPTAAQIETVFAGIGRLVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A5E83 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Nitrincola sp. KXZD1103 TaxID=2614693 RepID=A0A5J6LI20_9GAMM ----LLSELKRIESHLDARIGFAAHDTETGMRW-EYNADQRFPLSSTFKTLACAALLQRVD -TGSEQLTTSVSVSSSDLVTYSPVLEEYADTRITLFELCEATMTTSDNTAANLILQSLGGP -ENVTDFARQLGDKVTRLDRWETDLNQAVPGDERDTTTPNAMVSNLE-LLLGNVLSLESKR -YLQTWLVNNKVADGLFRSSMPSDWIIGDRTGAGGFGSRSITAVIWPAEREPVFVAFYITE -TTASFEERNAAIAQLGRVLIE-- ->[subseq from] Beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=A0A378ZTC3_9RHOB ---QLAETVAKIESRLNARVGVVLHDSGSGWSW-TNRADERFLMNSTFKAPLCGAILAAAD -AGTLSLDEELPILRADILSYAPVTEKKVGQSMSLSELCLATIDMSDNTAANLLINRLGGT -EAVTEFFRQNGDTVSRLDRLEPDMNTFKAGDPRDTTSPAAMSAALEKLLLGDVLSPQSRN -QLIEWMSHGGVTGALLRKTAPEGWHIADKSGSGDR-TRNIIAMITPPDRAPWIAVIFVSD -VKADFATRNAALQEISAAVI--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001124559C ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPEGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E554E ---KLNDDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0007647C6F ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISAVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] LAP family class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI000BB6BFF9 ----VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD -KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSEFCNAAITTSDNTAANLLLSTIGGP -EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK -KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN -THSSMNELNEHIAGIGDSVIKNw ->[subseq from] class A beta-lactamase n=1 Tax=Achromobacter sp. RTa TaxID=1532557 RepID=UPI0009DE03C7 ---ALNQALAQLEASSRGRLGVALLDTASGQTA-GYRADERFLMLSSFKTLAAAYILARAD -RGEDRLDRRIPITQADLQEHAPVTRLHVGPQMTLAGLCEATITTSDNTAANLMHRSYGGP -QALTRFIRSLGDTVTRHDRYEPELNRLHAGEPLDTTSPRAMTGTLDTLLFGQALKPQSRQ -LLQSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGSNDAGFAQAPGGAPIVVSAYLET -TGIPMPERDRIIAEVGGLVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. LA-2-3-30-S1-D2 TaxID=1637862 RepID=A0A1B4EU91_9BURK ---AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-46 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0004D9B684 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDEATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004CC1FB3 -hpAATRRLRDLEQEHQARIGVFAVNLTTGASL-LHRAHELFPICSVFKPLAVAAVLRDLD -HDGTELSRRIHYTESDVTKHAPITKLHVATGMTIRELCDATIRFSDNCAGNLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSAEPGRRTDTTTPYAIARTYRRLVLGSALDHPDRA -LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPIVLALFTHK -PTQPTASGD-------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE54_ECOLX ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVVIYTTG -SQATMDERKRQI----------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C793D ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Alcanivorax dieselolei (strain DSM 16502 / CGMCC 1.3690 / B-5) TaxID=930169 RepID=K0CJE6_ALCDB ---ALSRRCREWERRHGGRVGVAVWHLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -RGEESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAQLCEAAVAWSDNGAANLLIKGFGGP -GALTEFLRKSGDPVTRLDRLEPELNGYDANKESDTTSPAAMLGTLHRLLFGEVLSAQGRA -QLAAWMIANKTGDRRLRAGFPADWLVADKTGTSGLGYSNDIGVAWSPQRGAVLVTVYCEM -PKAEAGVRDRIIAEVAEMV---- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D32931 -------------------------------TV-SYRAAERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E29FDD ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAGLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGDDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TUMSAT_H10_S6 TaxID=1441612 RepID=A0A0I9QPR6_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDNATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007593C30 ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVAAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A6B06 ---AAQSQLDALEQASNGRLGVAALDTANGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB49_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGA------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI00045B541D ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGHTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. CCH5-D2 TaxID=1768765 RepID=UPI000829DFE1 -----AARLAALAARVGGRVGVVLRESGGETLL-ALGAQERFPLCSTFKVLAAAAILARVE -RGAERLERALPLGPDDLQSYAPVARAKVEAAMSLEEACAAALVWSDNTAANLLLDALGGP -EALTAFLRAQGDATTRLDRREPELNSALPGDPRDTTTPAAMAATLDRLLLGPALAPASRA -RLEGWMVGCRTGLKRLRAGLPADWVVGDRTGTGDNGTANTVALLRPPGRAPLVAAVYITG -TAGPAEARDAPHAEVGRIVA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI000DA943DB ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTTFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756E205 ----AQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGSYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] BlaMmas n=3 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A0S2SQE7_9MYCO ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E047B ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSNSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. P3 TaxID=2135430 RepID=A0A2R4JLW7_9ACTN ----VTAHLSELEARHGARLGVFAYNMRTRRSV-RHRADELFPVCSLFKTLAVAAVLRDLD ---PAALDRRVHYSADDVVENSEITKGHVADGMTIAELSAAAIWHSDNTAGNLLLRELGGP -AAITRFARSVGDRVTRLDRWEPELNSAEPWRTTDTTSPYAIARTYARLVLGDALRAPDRH -RLTDWMLGTVTSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWAPDGTPIVLAVQLTK -PDREAPYDHALIVETAGVLA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00046F2AA0 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLSGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium sp. 'caverna' TaxID=2202249 RepID=A0A2Z3V1H8_9ACTN ---EARRRLRALEASFKGRIGAYALDTATGKTV-TYRSGERFPLLSTFKASAAAAVLHKAR -TDPGLMDRVIHWKQSEVKANSPVTEKHVKDGLSVARLCEAAITQSDNTAGNMLLRQIGGP -AGLTRYFRSLKDPVSRLDRWETELNEWTPKAKRDTTTPAAMGQNLRGLATGTVLNAKDRA -RLNGWLRANKTGDERIRAGLPTTWTIGDKTGTTSYGAANDIAVVWPGKGAPLIMTIYTNR -RAAGALNDNKVIADTAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WM6378 TaxID=1415557 RepID=A0A0M8SWQ3_9ACTN ---DVADELSRLERTHHVRIGAYALDTATGRTV-TYRGNEKFPSLSTFKAMVCAAVLDKAR -REPGLMDKVIHWKKSDEVPNSPATAGQGDKGMTVADLCHAAITRSDNTAGNLLLGRIGGP -QGLTHYYRSLGDPVSRLDRWEPDLNVWKPGERRDTTTPAAMGRNLARTSLGSGLAPADRD -RLNGWLRATVTGDERIRAGLPNDWTVGDKTGTSDYGSANDIAVAWPKGGHPVIIAIYTNH -ATADAAADNAVIASTASTLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007535261 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429DTA7_9PSEU ------ADFEQLERAFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTSDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR -AEKDAKIDNKLLADATAAAIK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces parvulus TaxID=146923 RepID=A0A369UXA0_9ACTN -----SRSLAALERTHGARLGVFAWNTVSDRIV-RHRGDELFPACSVSKTPAVAAVLRDLD -RDGEFLRKVIRYGADDVDRYAPVTGENLADGMSVSDLCAVAITHSDNTAMNLILKELGGP -TAVTRFCRSIGDTVTRLDRWEPELNSAEPGRVTDTTSPLAMGKTYARLVLTGTLGTADRD -RLKGWLLANTTGDNRLKAGLPASWTVAEKTGTGDYGTTNDVGVAWTDKGEPVVLAVLSTK -ADAEAAADEPLLAEAARVIAD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3Q8GXR8_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -VGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPN------------- ------------------------ ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111CFB3E ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKVDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=2 Tax=Aurantimonas manganoxydans TaxID=651183 RepID=Q1YJJ5_AURMS ---RLADTVQGLEERLDARIGIFIRDSGSDWQW-GHREDERFLMASTFKSVLCGAVLEQAE -QGALALDEPVKIRAEDILSYAPVTETRQGSTMTIGELCLATADMSDNTAANLLLDRLGGP -QAVTAFLRGIGDAVTRLDRTEPDLNIFAPGDPRDTTSPKAMATSWETMLVGDGLRPASRQ -QLREWMRHGGVTGKLIRASTPKDWEVVDKSGGGQTHTRNLVAMLTPPGRAPIFVAIYLSD -SPADFSTRNAAVAEIGAAIV--- ->[subseq from] Beta-lactamase n=3 Tax=Stenotrophomonas TaxID=40323 RepID=A0A4Y5QBC7_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG -ASVDDDQRAAVLARVGTL----- ->[subseq from] class A beta-lactamase n=1 Tax=Carnimonas nigrificans TaxID=64323 RepID=UPI0004B5E2DD ----LSKQAARIEQTLGGRVGAYVMDTESGRTW-HYQADQRFPMASTSKVFMCAALLNNNG -HDGQQLESKAPLSEKQLVAHSPITSRYVGQRLTMAQLCSAALSVSDNTAANLILNQLGGP -QQVTRYARTLGDQVTRLDRFEPQLNEAAPGDARDTTSPRAMALSLQRLLLGDALPKAQRQ -QLLHWMENDQVADELLRAVVPRKWQVADKTGSGLHNTRNIVALLQPPHHKPVIVTIYMTG -VGQQMAQRDEAIRALGKTIV--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1H2GZY0_9PSEU ------ADFEQLERTYRARVGVYAVDTATGREV-TFRADERFAYASTHKVFSAGGVLQRTP ---IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -PDKDAEIDNKLLADATAAAMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A5CB5D ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDSAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429CHM6_9ACTN ------ADFEQLERTYRARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLRRTP ---VAELDRTVTYERKDLVVNSPVTEKHVATGMPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDARDTSTPRALAVGLRAFALGDALPEDKRK -ILVDMMRASTTGDQNIRAGVP-GWPVADKTGTAAYGTRNDIGVVWPPNRAPIVISVLTDR -SEKDAKIDNKLLADATAAAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=A0A1Q1PJ97_9VIBR ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F68D0CC -----------------------------GARV-GWISTALRVFESTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PLAI1-29 TaxID=2053010 RepID=UPI001438B923 ---AARRELRALEREHGARLGAYAHDTATGRTV-AYRADERFPMCSVFKTLGAAAVLRDLD -REGEFLARRIHYTERDVQRHVPVTSRNLAGGMTVEELCACSITHSDSAAANLLLHELGGP -TAITRFVRSLGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGRTYGSLVLGDALDAGDRR -RLTGWLLANTTSEHRFRAGLPGDWTLADKTGGGEYGTNNDAGIAWPPGRPPVVLTVLTTK -PDPDAGADDPLVAKAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SAJ15 TaxID=2011095 RepID=UPI0011852A56 -----TDELKALERKYHARLGVYAVDTGTGREV-AYRDGERFAYNSTFKAFVAGAILRKFP ---RGERERVIRYSKDALLPNSPISEKHVATGMTLTALCDAAVRYSDNTAANLLLEELGGP -KALDATLAELGDDVTEMVRDEPELSSWVPGEKRDTSTPRAFTEDLRAFTLGDVLPKAERA -QLTTWLRTNTTGDETIRAGMPKGWVVGDKTGTGYHGARNDMAVVWRPGAAPLVMTVFSYR -DAKKAAPDNKLIAEAAAVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Uliginosibacterium sp. TH139 TaxID=2067453 RepID=A0A2N4XU20_9RHOO ----FEDILASHEARLGGRIGLAILDTGSGALQ-TVKGTQRFPMMSTFKTLACATLLAEVD -AGRLRLETQVEIRREALLSYSPVTGKFVGQSFSLQQACDATMHTSDNTAANLVLEAIGGP -AAVTRFMRGLGDDVTRLDRIEPELNSALADDPRDTSSPVAMVRSLQALFFGDVLRPASRD -RLLQWMRGNEVAGPLFRATLPPGWAIADRSGAGDNGSRGITAILWPPQRAPLIVSLYLTG -TRADMPELNRSVAEIGREVFAAy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9G9_SHISO -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKLw ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. WM6378 TaxID=1415557 RepID=UPI00099B61EE ---DVADELSRLERTHHVRIGAYALDTATGRTV-TYRGNEKFPSLSTFKAMVCAAVLDKAR -REPGLMDKVIHWKKSDEVPNSPATAGQGDKGMTVADLCHAAITRSDNTAGNLLLGRIGGP -QGLTHYYRSLGDPVSRLDRWEPDLNVWKPGERRDTTTPAAMGRNLARTSLGSGLAPADRD -RLNGWLRATVTGDERIRAGLPNDWTVGDKTGTSDYGSANDIAVAWPKGGHPVIIAIYTNH -ATADAAADNAVIASTASTLV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium obuense TaxID=1807 RepID=A0A0J6VXK4_9MYCO ------DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDTFAMCSTFKAYASAAVLQRAQ -QGRLALTDAVLVGRSDIREHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP -SAITDFARSIGDDRTRLDRWETELNTAIPGDPRDTSTPRALGSGFRAVLTGDVLDGAHRQ -MLEDWMRANQT--SSMRAGLPGGWVTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS -ATPDADSLRPLIGEIAAAVA--- ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1N1E4_9ACTN -------ELADLERRYGARLGVYARNTRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTQENQATGMAMADVCAAAIQYSDNAAGNLLLRQLDGP -AGLTRFFRSLGDDVSRLDRWEPELNTAIPGDPRDTTSPEALAASIERLALGRALAAADRE -RFVGWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDMGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Citrobacter freundii TaxID=546 RepID=E7DK52_CITFR -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPM-------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium alvei TaxID=67081 RepID=UPI00138B42F5 ----VDDRLAELERRDNALIGLYATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQLAG -RGQLSLDNRVFVDPEAIVPNSPVTETHAGAEMTLAELCRAALQRSDNTAGNLLLKTIGGP -AGITEFARSVGDERTRLDRWEVELNSAIPGDPRDTTTPAALAIGYRAILAGDALSPPQRR -QLEDWMRANKT--SSMRAGLPDGWTTADKTGSGDYGSTNDVGIAYGPHGQRLLLAVMTRS -QADDAEGLRPLIGELTALV---- ->[subseq from] Beta-lactamase/transpeptidase-like n=1 Tax=Desulfoluna butyratoxydans TaxID=231438 RepID=A0A4U8YQ49_9DELT ---SLTKTIADIEQALGSPVGVSIYDAKTKTTW-SHHGDRRFPLMSTFKTLACAKALRDIE -AGALSFDDSVVIEKTSLVTWSPVTSNHVGQAFSLKQACESMMTMSDNTAANIVLTQTGGP -QALTSFARSIGDTVTRLDRMEPDLNEARKGDLRDTTTPDAMAGNLRTLVLGNELSDASKA -LLTNWMRGNKVSGSLLRSVLPKGWDIADRSGAGGHGSRGIAAVVWPAPEEPLVVCIYLTQ -TTASFEELNKSIASIGRAIFALy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-4428 TaxID=1609137 RepID=A0A0F0H8V7_9ACTN -----VRRLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKAPAAAAVMRDLD -RDGGFLARRIRYTAQDVAGGGSVTGENIAQGLTVAELCSAAIAQSDNCAANLLLRELGGP -SAITRLCRSVGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSGDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIVWPPGRPPVELAVLTTK -PEAAAPRENALVARAAEVLA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0009B638F5 ---KLNEDISLIEKQTSGRIGVSVWDTQTDEHW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLTGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007552FD7 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFDDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix sp. CB00851 TaxID=1835005 RepID=UPI0009FAA2DA ------DHLVELERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVLHRHP ---LSHLDTVVTYTEADLMASSAITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYLRALGDTVTRADRFEPHITTAVPGDPRDTTTPRAIGTDYRRIVLGDVLPPDQRA -FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDTAPLVVSIMSSK -AAADAGYDQALLAEAAAYVV--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. Leaf183 TaxID=1736291 RepID=A0A0Q5RUM5_9MICO ------ASFRQLERQHDARLGVVAVDTGSGHRV-AYRSGERFAFASTNKVFIAAAVLAGSS ---DADLDTVVHYDRGDLLSYAPVTSRFVDSGMTVRELVDAALRFSDNTAANLLVERVGGP -DAVERYLRGIGDRTTNVDRLEPELNEATPGDPRDTTTPAQFVTDLRKVLLGTTLDTTDRT -FLRDTMLDNTTGAATVRAGVDPTWPVADKTGTGEYGVRNDIAVVYPAGRAPVVVVVMTSR -DQPDATTDDALVAAATKAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces chartreusis TaxID=1969 RepID=UPI000D38220C ---ATTDRLRLLERQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD -RDGEFLGRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR -LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK -PAQDAAWDDALVAETAALL---- ->[subseq from] BlaMab n=5 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A0U0X1M3_9MYCO ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase (Penicillinase) n=2 Tax=Mycobacteroides abscessus TaxID=36809 RepID=A0A655KS92_9MYCO ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=3 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0I9QPS5_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKDWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001120187E ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLSEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=2 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=A0A0U3P9E6_9RHOB ---QLAETVTKTESRLNARVGVVLHDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD -AGTLTLDEELPVLQSDIVSYAPVTEKKVGQTMPLSELCLATIDMSDNTAANLLINRLGGT -EAVTEFFRSTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMAATLEKLLLDDVLSPQSRN -QLTEWMSHGGVTGALLRKTAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD -VKADFATRNGALQDISAAVID-- ->[subseq from] Beta-lactamase n=1 Tax=Haloactinopolyspora alba TaxID=648780 RepID=A0A2P8DE99_9ACTN ----TDDAVHRLERAYDTTIGLAAANLATGARL-VHRAGDRFPILSVFKTLAVAAVLRDHD -LHGETLRRRVWFPPADVLEYAPVASEHVDTGMTIEQMCAAVLHLSDNTAGNLLLREVGGP -QGQTAFVRSLGDRTTRLDRWEVALNTAIPGDVRDTTSPAAIARTFARLLTGTALHRHDRA -RLRQWMLENRTGDARLRAGLPDGWRVADRTGTGAYGTANDVGVAWNPAGEPVVIAALTRR -DDQDATADETVLADVAGLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZF6_9BACT ----ASHPLAQIEARTGGRLGVAVIDTANGRQW-QYRGSERFPMCSTFKLLLAAQMLQRDQ -QGLDSLQQRVTYPRSALVPYSPTTETQADGALTVAELCEATVVLSDNTAANLLLARQGGP -QGLTQWLRDMGTMHTRLDRLEPALNSATPGDERDTTTPLSMARAVVALAKGPHLDAGHQA -QLLQWLKASPTGAKRLRAGMPPGWLVGGKTGTGDNGTANDVVLVWPHHRQPLVVSAYLTQ -TPLAPAARDAALAEVGQAVAHWf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas humi TaxID=405444 RepID=A0A0R0CGG3_9GAMM -----ARDFTALEAESGGRLGVCLWHPASGARY-GHRMDERFPMCSTFKFLLSAAVLHRAD -HGQLSLDQRVPVRAADIINHSPGTERHVGKDMTVRDLCRTTMVTSDNAAANLLLPLVGEP -AGLTTFLRAQGDAITVTARYEPDANRFAVGDPRDTTSPAAMAGNLQRFVLGDALSPASRQ -QLADWLIDNETGDARLRAGLPQGWRVGDKTGSNGKDATNDIAVLWPEGGTPWLLASYLQG -SPLDDDGRNGILRRVGELA---- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5EYJ1_9ACTN ---RATKELRALETSFKGRIGAYAIDTATGRTI-AYRSGERFPLLSTFKTMACAAVLHKAR -TQPGLMNKRVRWTARDLVDYSPVTEKHVKDGMTVAGLCDAAITMSDNTAGNMILKQIGGP -AGLTRYFRSLKDRVSRLDRWETELNDWTPKSRRDTTTPSAIARDLRAVTYGKALNAKDRA -QLNAWLIANTTGDARIRAGLPKTWTIGDKTGTNSFGGGNDIAVIWPNRAAPIIMAIYTNR -RP-GLAADDKTIAKTAEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. HDW3 TaxID=2714923 RepID=UPI00140BA9B6 --tQMAASLKQLEAKAQGRLGVHVVDTGSGQEF-GYRSDELFMMLSSFKLLASALVLARVD -RGEESLERRIPYRKQDLVPWSPVTDAHADGDLTLAQLCHATITTSDNTAANLILASFGGP -EALTTFARQIGDNVTRLDRNEPDLNMRLGTNSLDTTSPRAMAMSMKKVLVGDVLAPSSRK -LLREWLIANTTGGKRLKAGLPVGWTIGDKTGTNKS-DANDIGILFPPQRPPILVTAYLAD -SSASSQIKDETLAEVGMLAT--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A4FHM7_SACEN ----HDDHLAGLERKFGARLGVYALATGTGATV-AHRADERFAFCSTFKALATAAVLHRNP ---MSHLDALVTYGEADLMKSSVITRQHVSTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYARGLGDEVTRMDRVEPLIVEATPGDPRDTSSPRAFGTDFDELVLKDALPEDKRA -FLRDLLQRGTTGARRIKAAVPPGWTVANKTGTGDYGTLNDIAVVWPPDSAPLVIAIMSSK -PAKDAEYDEALLAEAAAHVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755C5F9 ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. S816 TaxID=2283197 RepID=A0A4S2IY51_9ACTN ------GELTDLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLAVGRALAAPDRE -RFVTWLKGNTTSGARFRAGLPEGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces galbus TaxID=33898 RepID=UPI00052E53C2 ----LSRQLGELEREYSARLGVFARDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD -RDGEYLAKRIHYTKEYAEAYSPITGTNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALRDADRE -LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPLVLSVLSTK -YDPAGPTDNPLVARAAGLVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Tatumella sp. OPLPL6 TaxID=1928657 RepID=A0A2G8C4L5_9GAMM --eEFKKELSNLERSSQGKLGVYLIDPSAKQSF-SYNGDERFPFCSTSKILVTAKLLHDSQ -SLPILLDSKVDIKQTDLVNYNPITSKNVGKSMTVSELSMAALQYSDNTAMNLLLQKAGGI -DAINKFARTLGDKDFLLSRNEPSLNTSIPGDIRDTTTPRSMASTVEKLTLGNGLINEKKK -TLVTWMKGNTTGGASIKAGIPSTWVIADKTGTGDYGTTNDVAVMWTDKNKPLILVTYFTH -FEKDAEPRKDVLSKAAKIVTSY- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000CD33EC3 ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATLLSDMD -DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075467DC ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S115 TaxID=1394650 RepID=A0A0I9QPS2_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPGLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-23 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00046D5C8C ---NLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus normandii TaxID=1137989 RepID=UPI000D71D0E8 ----VAGAFAALEERFDARLGVFAVDTGSGRTL-EHRADERFAYASTIKALAAGALLARTS ---PADLERGVPINAGDLAAYSPVTEGRVGGAMTLAELCDAAVRFSDNTALNLLLRELGGP -AGLDAALEGIGDDVTEVARTEPALNSAVPGDPRDTTTPRALAGSLRF-YAVDGAAEDDRA -LLADWLRRNTTGDALIRAGVPGDWEVGDKTGTGAYGARNDVAVLTPPGRAPLVLAVMSSR -DEPDAEHDDALIAEAARVVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751B91F ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Agrobacterium rhizogenes TaxID=359 RepID=UPI0005524533 -----QQRIAALESKHPGRIRVSILDMASGKRI-EHREGERTLICSTFKVLAAALVLTRVD -KGEETLDRRIHYLKSDLVESSPATRSQLGNGMTVAELCAAAMTLSDNTAANLLLASFGGP -KALTAFCRSLGDDITRLDRMEPALNYDTPDDQRDTTTAAAMLENLRRLLFTDLLSAASKS -QLAAWLMINKTGDTRLRAGLPKDWLAGDKTGTNGDGNANDIAVLWPTNRAPIIVTAYCEI -PGIAADERNSIIAEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE4EE6 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A572A0 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIPYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. WMMA1423 TaxID=2591108 RepID=UPI0011475956 ------ARFAALERRHGARLGVYALATGTGAEV-AYRADERFAFCSTFKALAAAAVLHGNP ---LGHLDDRVTYTRADVDSISPITRDRVATGMTVRELCDAAIRYSDGTAGNLLMRDAGGP -AGLTAYLRGLGDTVSRMDDYEPELNRVRPGDPRDTTTPRAIAADYRAIVLGDALEPAKRA -LVRGWLERSATGARRVKAGLPRGWKAASKTGTGDYGRANDIAVVWPPRGGPLVVAVMSDR -RGYGAPPKNALIAQAAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Delftia acidovorans TaxID=80866 RepID=A0A2M9PVE8_DELAC --qAFRTELARIEKSVGGRLGVAVLEAESGASV-DHRGDERFVMCSTFKLLLAAQVLDRVQ -QGDERLSRRVHYASSRLVPYSPASGPRAGDGMTISELCEPPLVLSDNTAANLLLDASGGP -QALTQWLRASGDETTRLDRMEPELNEGLPGDERDTTTPLAMVQSMQRLLLGSVLDGHGRA -LLQQWLVASRTGDKRLRAGMPAGWRVGGKTGTGDRGTANDAVIAWPPQSAPLLVTGYLTE -CPADAPQRDAALASAGKAAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI0007561031 ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMADMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAAIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005E27128 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYPRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000C268544 ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRSL -SEPGLLDQRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces atriruber TaxID=545121 RepID=UPI0006E331A2 ---RLASRFTALERKHGGRLGVHALATGTGATL-THRADERFAFCSTFKTLAAAAVLHHRP ---LARLDERVTYTAADVDSISPVTEKRIATGMTLRELCDAAIRYSDGTAGNLLMREIGGP -AELTAYLRRLGDSTSRMDHYEPELNDVRPKDPRDTTTPRAVAADYRALVLGDALPAAKRA -LLEDWLRRNATGERRIRAGLPEGWRVADKTGTGNWGRANDIAVVWPPHADPLVLAVMTDR -PGRDAPPVNAFIAEATELIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. PID23_8 TaxID=1583767 RepID=A0A3A2HWH8_9VIBR ---QLNVNLAAIEQHIAGRIGVSVWDTQTDEQW-DYRGDERFPMMSTFKTLACATMLSDMD -SGKLNKNATAKVEERNIVVWSPVMDRMTGQTTRVEHACEAAMLMSDNTAANIVLRSVGGP -RVVTMFLRSIGDKATRLDRYEPGLNEATPGDKQDTTTPNAMVNTLHTLLEGEALSYESRT -QLKIWMQDNKVSDSLMRSVLPKDWSIADRSGAGGFGSRGITAVIWKENHKPIYISIYLTE -TELSLQARDQAIAKISQLVLEEy ->[subseq from] class A beta-lactamase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=UPI000B891C45 ----LENRIKEIEHALGARVGVSLYEVETSESW-SYKGDIRFPLMSTFKTLACAKTLLDVE -QKKVSFDDSVVIEKTSLITWSPVTKHHAGQAFSLKQACAAMMIMSDNTAANIVLDKTGGP -TALTAFMRSIGDAVTRLDRMEPELGEALEGDVRDTTTPNAMADSLHVLLFGDVLSKASKT -QLTQWMRSNKISGSLLRSVLPDGWTIADRSGAGGHGSRGITAVVWPETQPPFIVCVYLTQ -TKASFDERNKAIAEIGRELFKLy ->[subseq from] CBP family penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Clostridium sporogenes TaxID=1509 RepID=UPI0005F89AE6 ----YNSAFSKIESDYGVKLGVYAFDTETNKEV-TYNADKRFAYCSTFKSLISGAILQKYS ---SDQLKQVIKYSPKDVLSYAPVTKNHVDKGMTIEELCDAAVRFSDNTAANLLINLIGGP -NGFKSALNQLGDTVTEPARIEPELNVATPGDNRDTSTPRQLSIDLKEYTTGNILSDDKKK -ILINWMSGNATGDKLIRAGAPKDWMVSDKSGTGSYGTRNDIAIVIPSNKKPIFIAILSSK -NDKDAKYDDKTISEASKIVFDYf ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00111F7325 ----AAADFAALEKASGGRLGVTVLDTRSGRRIgGHRQAERFPMCSTFKSMLVAHVLSLAD -AGRVSLDSRVAVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP -AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLALFAVGDGISAASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEEQRAAVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752AA7E ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAEAMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Leifsonia sp. Root227 TaxID=1736496 RepID=A0A0Q8UQ19_9MICO ---ATTRAFAALERSHAAALGVTAIDTGSGRTV-GFRADERFPFASSNKTFIAAATLQRAT ---TADLDTVIHYTQADLLDYAPITSRFVDTGMTVRELIDAMLRFSDNTAANLLVARLGGP -DAVEQWMRGIGDRVTNVDRVEPDLNAAIPGDPRDTTTAAQFATDLRSVVLGKTLETADRT -LLRNTMLDNTTGDDTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPIVVVVLTRK -DAPDATPDNALLAEATKIAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Mannheimia haemolytica TaxID=75985 RepID=A0A3Q8G682_MANHA ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHANRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTEEAKFNNKLVEDAAKQVFH-- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003A4819E -----QPDFAALEKAFDARLGVYAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLARTVTIRQSDLVPNSPITEKHTGEQMSLQSVLDAALRYSDNTADNVMFGEIGGP -AGLAAELRRLGDTVTRVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDAGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGTADYATRNDIAVLWPPRRAPIVLAVLSDR -PQKDAKTDDKLIAQAAAAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CF7CF ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVAERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_032 TaxID=2175650 RepID=A0A2W1QV61_9MICO ---ATTRALDALERRDDARLGLVAIDTGSGATV-THRAGERFAFASAAKVFIAATVLDDAR ---SGDLDAVVPIEQRDLLSYAPVTSQHVGSGMTVRALLDAMLRSSDNTAANLLVARVGGP -SVVQQWLRGIGDQVTQVVRVEPDLNEATPGDERDTTTPAQFAADLRTVLLGDALRPEDRK -MLVETMAGTTKGAATIRAGVPTGWSVADKTGTGSYGVRNDVGIVTPPGRAPIVLVVMTSR -SRADAKPVDALVAAATKVTV--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI001110F326 ------ADFAALEKASGGRLGVTVLSTGNGRRIsGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPLARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax carolinensis TaxID=553814 RepID=A0A240TTT7_9BURK ---QWSDTLAGIERAAQGRLGVALLDTGSGLAL-GWRQDERFAVASTFKLVLAGWMLALVD -QGRERLDARVHYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVQSLGDGITRLDRTEPTLNEAAVGDPRDTTTPLAMLQTMQKLVLGDALTTLSRA -WLQRWLVETGTGDQRLRAGVP-GWTVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR -STAQPAQRDAAIAQVARAVAT-- ->[subseq from] Beta-lactamase n=1 Tax=Granulicella sibirica TaxID=2479048 RepID=A0A4Q0SY32_9BACT -----PAAFARLEQTNGGRLGVAVLDTATSERS-GHRAGERFPMCSTFKFLLASAVLQRVD -HHQETLDRLAAVPPKPLLGNSPLTEPHAGATMSIASLCHAALTRSDNTAANILLESIGGP -AGMTAFCRAIGDPVTRLDRTEPTLNESLAGDPRDTTSPVSMVTNLKSILLGNVLAQSSRE -QLTTWMEANLTGLDRLRANLPTAWRAADKTGSNGEHTTNDIAVLWPANRPPVIVAAYITQ -CIGPESKRATMLSEIGRLVR--- ->[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus normandii TaxID=1137989 RepID=A0A317QLD0_9ACTN -------AFAALEERFDARLGVFAVDTGSGRTL-EHRADERFAYASTIKALAAGALLARTS ---PADLERGVPINAGDLAAYSPVTEGRVGGAMTLAELCDAAVRFSDNTALNLLLRELGGP -AGLDAALEGIGDDVTEVARTEPALNSAVPGDPRDTTTPRALAGSLRF-YAVDGAAEDDRA -LLADWLRRNTTGDALIRAGVPGDWEVGDKTGTGAYGARNDVAVLTPPGRAPLVLAVMSSR -DEPDAEHDDALIAEAARVVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alba TaxID=53437 RepID=UPI0005A63392 ---DVEAEFEALEAEYDTRLGVYALDTGSGEEV-EFREDERFAFASTFKSLLAGVVLSENS ---LEEMERVITYDEDVLVSHSPITEENVGTGMSLLELCDATVRFSDNAAANLLLEELGGP -EGFTESLEETGDDVTTLDRYETDMSAAVPGDERDTSTPEALAGSLEAFTLGDVLPEDRRE -VLVDMLVRNMTGDAVIRAGVPEGWVVGDKTGTGGYGTRNDIAVVWPEEGDPIVLAVLSTM -EVEDAEPQDSLIAEATEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus halodenitrificans TaxID=1482 RepID=UPI00136B1F91 ------------------------IDTGTNQRL-QYNPDDRFAYASTFKVLASAILLKQNS ---IEDLERVVTFSKDDLVTYSPVTEKHVDTGMTLGEISEAAIRYSDNTAANLLLEELGGP -EQFKQALRDLGDHVTQPERFETELNDFTPGKKRDTSTPKAMVNTLKKVALDDFLPDDKRE -LLHNWMKGNATGDKLIRAGAPAEWVVGDKSGAGSYGTRNDIAIVWPPDREPIVIAVMSRH -EEEDAEYDDELIAKAAEIALN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. OK838 TaxID=1882762 RepID=A0A239NLA0_9BACI ---TAMEKFKQLEKEYDARLGVYAIDTGTKETV-EFRENERFAYASTFKALAAAVLLKQNP ---ISVLEEIRTFTNEDIVTYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGESRDTSTPKAIATTLGVFGISEYLPADKQE -IFTNWLKGNTTGDSLIRAGVPESWVVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR -NEENASFNDKLIAKAAKVIAQAy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092C54EE ------DELASLERDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium goodii TaxID=134601 RepID=A0A2M9FBU0_MYCGD --------IADLERRHNALIGIFAANLDSNRTV-AHRADEPFAMCSTFKTYLAARVLQKAE -RGELSLDDRVFVDPSVLLVNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLTKIGGP -AEITAFARSIGDQRTRLDRWEIELNSAIPGDPRDTSTPAALGGGYRALLAGDALSTPQRQ -RLDEWMRANQT--SSMRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLAVMTRS -RDDDAPGLRPLIGEVTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. YBE204 TaxID=1282363 RepID=V4QLD1_9CAUL ----LGKRLMEIQARHGGRIGVSTLDTAADGSL-NLNSTERFAMCSTFKWVLAAAILKAVD -EGKLTVAQEVKYSKADIVDHAPVTTMHLEKGMTIGDLCSATVAVSDNTAANLLLPLIGGP -EGLTAFVRGLGDTVTRLDRTEPELNSNVEGDARDTTTPDAMSGLLRTVFTGKVLTPKSLS -LLTDWMKATTTGPDMIPAGLPQGWTVGHKTGRGANGAVNDVAVIWPTGEVPIFLAIYTTG -GTLDDKARNAIVADVTRLVVD-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000D4F99AE ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium glycinendophyticum TaxID=2589807 RepID=A0A504U5L1_9RHIZ -----SAAARHLERQLGGRLGLMVVDIETDRRW-GYRADERFAMASTFKALACAALLDAG- ---EAVQGRSMTIEAKDLQTYSPVTSKKVGSAMTAAELCAVTLATSDNTAANLVLKALGGP -KRVTAFLRSAGDMVTRLDRREPALNEAKPGDPRDTTTPQAMATTIGDLLLGDTLTADARG -RLTGWMEANAVADGLLRAGVPKDWRIADRTGAGGHGTRGIVAVMWPPGRLPVVAAIYLTE -TEASMATRDAAIAEIGRVIAA-- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T278_9BACT -------AAQQAETELNARVGLVIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPGQAPLLAAIYLTQ -TDA-------------------- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=A0A393XUG1_9MYCO -----DDQIADLERRHNALIGLYASNLDSGRTL-AHRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDREAIVPNSPITETHVGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSALPGDPRDTSAPAALAAGYRQVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDADNLRPLIGELTAAV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix carnea TaxID=1280637 RepID=A0A2P8HZK1_9PSEU ------DHLAGLERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVVARHP ---LSHLDTVVTYTEADLMASSAITRQHVATGMSVRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYLRTLGDTVTRADRFEPHLTTAVPGDPRDTTTPRAIGTDYREILLGDALPPDRRA -FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDAAPLVVSIMSGK -ATADAEYDQALLAEAAAYVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346CG34_KLEPN --------IKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGTGQRGARGIVAL----------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758E7E9 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=A0A3L7B4G1_9ACTN -------HLVSLERKFDARLGVYALATGTGATI-AHRADERFPFCSTFKGLAAAAVLHRRS ---LSDLNSVVRYTADDLMDSSVITRRHVATGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -GELTAYVRGLGDTVTRMDRIEPAVASGTPGDPRDTTTPRALSTDYHRIVLGEALPPDRRA -FLRDLLERNATGAQRIRAGVPRGWTVADKTGTGGYGTVNDIAVVWPPTSAPLVIGIMSAK -AEKDADYDQALVAEAAAYVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidisphaera sp. L21 TaxID=1641851 RepID=UPI00131D34E4 ------QVFAAIEARRGGRLGVAVLDTATGRTA-GYRQDERFPMCSTAKLPTAGAVLAHVG ---VAGLQRRIHFPKHDLVVHSPLTAPHADTDMTLDAICAAALSQSDNTAGNLMLHIIGGP -AGLTRYLRTLGDEMTRLDRWETALNEAKPGDVRDTTTPAAMLADIQALTLGHALPAPAKA -SLLGWLRGNQVGDARLRARLPPGWQVADKTGTGDFRTSNDAGLLFPPNGPPIIVAAYLTE -GSADDAVREAALADVGAAVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8998 TaxID=2184557 RepID=A0A3N8GWN5_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDESLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMADMVQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPARAPIVLAVSFTQ -PRADAAAREDVVASAARIATSAf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. Leaf261 TaxID=1736311 RepID=A0A0Q4UYV1_9MICO ---ATTRAFAALEQQYGAQVGVRVLDTGSGNTL-GYRDDTRFAFASTSKLLTAGLLLRTAS ---DAELDTVVHYDAADLLSYAPVTSQHVATGMSLRDLVTAALQVSDNTAANLVTEHLGGP -AAVQSALRTLGDSTTNVDRTEPDLNTATPGDVRDTTTPHALATDLRRFAVGDLLTPARRT -LLVSLLEGNTTGGPYVRAGVPAGWTVGDKTGNGSYGTRNDIAVVTPPGRAPIIVVILTNR -GSQDASSDDALIADVTRQVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium neworleansense TaxID=146018 RepID=A0A0H5RLE5_9MYCO ----IDDQIAELERRHNALIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLENRVFVEPAAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDDRTRLDRWEVELNSAIPGDPRDTSTPAALAGGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAMMTRS -QADDADNLRPLIGELTAL----- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. A0592 TaxID=2563099 RepID=A0A4V3TAV3_9ACTN -----VRQLRALEREYGAWVGAYARDTGTGRTV-LYRADELFPMCSVFKTPAAAAVMRDLD -RDGEFLARRIHYTQEDVTSGGSVTGANVAGGLTVAELCSAAIAQSDNCAANLLLRELGGP -TAITRFCRSVGDRTTRLDRWEPELNSAEPSRVTDTTSPRAIARTYGRLVLGDALAPRHRE -LLTRWLVSNTTSGDRFRAGLPRDWVVGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -ADPAAPREDALVARAAGVLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C8CE53_ECOLX ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEVDKVAGPLLRSALPAGWFIADKSGAGERGSSGIIAALGPDGKPSRIVIIYTTG -SQATMDERNRQI----------- ->[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-45 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000541AE92 ---KLNADISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPGLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. YAU14A_MKIMI4_1 TaxID=2072408 RepID=UPI000D542A00 -------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLPPPSRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEAQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax sp. NB1 TaxID=1943571 RepID=A0A4D4JNK7_9BURK ---AWNDALATIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDHRLHYGRDAVIAHSPVSGPRAGDGLTVAELCAATVSLSDNTAANVLLAQHGGP -ASYTAFVRSLGDAATRLDRYEPHMAEAAAGDLRDTTTPQAMLQTLQKLVLGDVLTPVSRA -LLQRWLLETSTGDNRLRAGAP-GWKVGDKTGTGASGTANDIGVLWPAGGAPVLVTCYLTR -SAASPQQRDAAIAQVARAVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura chibensis TaxID=392828 RepID=A0A5D0NQ72_9ACTN ---KVAARLRALEKARGVRVGAYAVDTGTGRSV-SYRGGERFPFASSFKAMACGAVLRKAD -SDPALMDRVIRYEKSDLADFSPVTEKHVGTGMTVADLCHATITRSDNTAGNLVLKLIGGP -PGLTAFLRSLGDASSRSDRAEPGLNHWRPGEPRDTTTPAAWAGDLRALAVGDALAPPDRT -RLVGWLKATVTGGERIRAGLPKTWTVGDKTGTAGYGNAVDVAVAWPPGAAPLVMAVLTTR -PRADAEADEKAVAETARILAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AA0539 TaxID=1210045 RepID=UPI0004753980 ------GEFARLEDAYDARLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLEEYG ---LAGMDEVIPYGEEDLLPNSPITEERLAEGMSKSDLCDATVRYSDNAAANLLWDTIGGP -AGLQERLAGLGDDVTRMERWETELNEAVPGDERDTTTPEAFAGNLAGYVLGEVLPEPERA -QLTEWLVTNTTGDELIRAGVGEGWTVGDKTGGGGHGTRNDIAVLWPDSGPPLVLAVFSTR -EEPDADWDNALIAEAASVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4UH42_9ACTN ----AVKELRALETSFKGRIGAYAIDTATGRTI-AYRSGERFPLLSTFKAMACAAVLHKAR -TRPGLLKKRVRWTARELVDYSPVTEKHVKDGMTVAGLCHAAITMSDNTAGNMVLKQIGGP -AGLTRYFRSLDDRVSRLDRWETELNDWTPKSRRDTTTPSAIARDLRAVTYGKALNAKDRA -QLNAWLIANKTGDARIRAGLPKTWTIGDKTGTNSFGGGNDIAVIWPGKGAPIIMAVYTNR -TP-GLAADDKTIAKTATILA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084B52F8 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACASMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D57C3 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACAAMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKSVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B7946 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A127DCD0_9BACI ---TVMEKFKQLEKEYDARLGVYAIDTGTKETV-EFRENERFAYASTFKALAAAVLLKQNP ---ISVLEEIRTFTNEDIITYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGESRDTSTPKALATTLEVFGISEYLPADKQE -IFTNWLKGNTTGDSLIRAGVPESWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR -NEENASFNDKLIAKAAKVIAQAy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FEA09 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LHW50302 TaxID=2250578 RepID=A0A367EK46_9ACTN ---RVTEALATLEKRHDRRLGLYMRDTGSGRTV-EYHADERFGFCSTAKVLQAAALLEHAD ---EAQLNRVITYERDDLEDHAPITRKHLDTGASVRALMKAALQYSDNTAANLLFEQLGGP -AGLQRKMRGLGDRTSVFDRTEPDLNDTPPGTTHDTSTPRALAQDLRRFLLDDALAPDRRE -LLASWMRGNTTGDDLIRAGVPSGWKVADKTGSGTYGTQNDIAVAWRPHGAPVIIALMSRG -HDKDSASDKALMAEATKAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI0007A3E9D8 -------RLIELERKYDARLGVYARATGTGVTV-AHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVTYTRDDLLKNASVTPRYVDTGMTIRQLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYARSLGDPVTRMDRIEPAITEATPGDPRDTTSPRAFGEVYHRIVLGDALPADKRD -FLRDLLERNATGAQRIRAGTPQGWRVADKTGTGDYGTLNDIAVVWPPDAAPLVVAIMSSK -ATRDAAYDQVLLAEAAAYVMD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. KS_5 TaxID=1881018 RepID=UPI000898A520 ---ATTDRLRELERQHGSRLGVFAYNVRTRKTV-THRPDELFPMCSVFKTLASAAVLRDLD -RDGEFLRRRIHYTEADLPEGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR -LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK -PAQDAAWDDALVAETAALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces yerevanensis TaxID=66378 RepID=UPI0005255915 ---DISRALNDLEREHSARLGVFGRNTVTGRSV-LYRADESFPMCSVFKTLAAAAVLRDLD -RHGEFLALRIRYTEQDVEEGAPVTEENLANGMTVAELCEAAVAYSDNCAANLLLRELGGP -TAITRFCRSIGDRTTRLDRWEPELNSAEPGRVTDTSSPAAIGWTYAKLALGDALTPRDRR -QLTAWLLANTTSTNRFRAGLPEDWALGDKTGTGKYGTTNDAGIAWTPDGTPIVLAVLSTK -PDPDTPMDEPLVAKTAALLAK-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084A32E4 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVIWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Roseicyclus mahoneyensis TaxID=164332 RepID=A0A316GFJ9_9RHOB --qTLAATIDRIEQDLDARVGLLIRDSGSDWSA-TYRADERFLMTSTFKTMLCGAVLHRVD -AGDIDLEERIAIETADILDYAPVTETMVGNTMSVGALCHAALDMSDNTATNLLIDRIGGT -QSVTAFLREIGDPVSRLDRREPEVNTFAPDDPRDTTTPAAMASTMEVLLAGDALSPQSRA -QLVDWMSAGGVTGALIRASTPEGWHVADRSGSGNF-NRNIVAMVTPPDRAPYFIAIFLSD -AQADFDTRNAAVIALSDAVMQ-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S105 TaxID=1394641 RepID=A0A0I9QQ02_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDME -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Pannonibacter phragmitetus TaxID=121719 RepID=UPI000F01A607 ---QLAETVAKTESRLNARVGVVLYDTGSGWSW-ANRADERFLMNSTIKTPICGAILSAAD -AGTLTLDEELPVLQSDIVSYAPVTEKKVGQTMPLSELCLATIDMSDNTAANLLINRLGGT -AAVTEFFRQTGDTVSRLDRLEPDLNTFKSGDPRDTTSPAAMSATLEKLLLGDVLSPQSRN -QLTGWMSHGGVTGALLRKTAPEGWHIADKSGSGDQ-TRNIIAMITPPDRAPWIAVIFVSD -VKADFATRNGALQDISAAVID-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. C1-1 TaxID=2491024 RepID=A0A3N9Q430_9BACI ------AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIADATEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas terrigena TaxID=32013 RepID=UPI000E189C7F ----ASHPLAQIEARTGGRLGVAVIDTANGRQW-QYRGSERFPMCSTFKLLLAAQMLQRDQ -QGLDSLQQRVTYPRSALVPYSPTTEAQAGGALTVAELCEAAVVLSDNTAANLLLARQGGP -QGLTQWLRDMGSMHTRLDRLEPALNSAVPGDERDTTTPLSMARAVVALAKGPHLDAGHQA -QLLQWLKASPTGAKRLRAGMPPGWLVGGKTGTGDNGTANDVVLVWPHHRQPLVVSAYLTQ -TPLAPAARDAALAEVGQAVAHWf ->[subseq from] Beta-lactamase n=1 Tax=Goodfellowiella sp. AN110305 TaxID=1892852 RepID=A0A5B2XUE2_9PSEU --qAAEAAFAALEAKFGGRLGVSAVDTGTGRTV-GHRADERFLMCSTHKVFVVAAILALRG -RQPGLLDRLIRYDRSQLLSYAPVTSQHVADGMTVSALCEAAITVSDNTAVNLLQQVLGGP -AAATAYVRTTGDQVTRLDRLEPDLNVGAPGDERDTTTPAQFAADLRTLALGDTLDPAGRD -LLTGWLTAATTGGALVRAGLPAGWRAGDKSGSGAAGEVNDVAVVWPPNHAPLVVTVFTAP -TDRASKAGQATVAGAASIAVK-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14A_NAIMI4_1 TaxID=2072412 RepID=UPI000D53F5CC ------ADFGALEKASGGRLGVTVLDTGSGRRIaGHRQDERFPMCSTFKSMLVAHVLHLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -PALTAFLRAQGDAVTRNDRYEPEMNRFAKGDPRDTTSPAAMAASLARFAVGNGLSAASRL -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGAPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus shacheensis TaxID=1649580 RepID=UPI00073FFC58 ---DTNNVFSQLEEEYDANLGIYALNTGTNQII-SYREDERFAYASTHKALAAGVLLQQND ---VDELDQTIGITKDDLVNYNPITENYVGEEMTLKELSEASMRYSDNTAGNLILEQIGGP -EGFKEALRDMGDGVTHPKRIEPELNEFIPDETHDTSTPEALAHSLQKFTIGDALPQEKQE -LLTDWLKQNTTGDPLIRAGVPEDWEVGDRTGAASYGTRNAIAIIWPPNEDPIFLSVLSNK -DQEDADYNDELIARATEEVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Ideonella sp. B508-1 TaxID=137716 RepID=UPI00034541B0 ---ALQQALRDIEARAKGRLGLAVLDTGSGRRW-LHRADERFLLCSTFKLLLCAQVLERAA -RGEERLDRPLSFGRGDLVEWSPVTKKAVGRGLSVAQLCEATMTTSDNTAALLLLKTQGGP -AGLTRWLRAHGDTQTRLDRSEPDLNLADPTGEWDTTTPATMADTVQRLCLGAGLPKTVQA -QLQAWMKASTTGAQRLRAGLPTGWQIGDKTGTGD-GISNDVAIVWPPGQAPWVVVAFLSD -CRSPRDVQQACLADLGRL----- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis thermoflava TaxID=84480 RepID=UPI00056D115B ------VDFADLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVTYTDADIQPNSPVTKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP -AGLAAVLREIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGDALPADKRD -LLVGIMRRNKTGTELIRGGVPSEWPVADKTGTGDYGTRNDIGVIWPPGRAPIVLALMSSR -TTADASYDNKLLAEATSRVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinopolyspora mortivallis TaxID=33906 RepID=UPI0003A0D2F8 --nTVRAEFTRLEQRFGARLGVHALDTGSGEVV-THRADERWAFCSTMKTFTAAAVLRRNT ---VEDLDRRITYTRAELVPYSPVTEKHVDSGMTLRETLRAALRVSDNTAQNLLLRELGGP -EGLRRELRELGDTTSHVDRYEPELNETAPGDVRDTSTPRALAANLREVVLGDALAPEKRK -ILRGAMRNPPLTEELVQAGTPEGWEIEDKSGAGNHATRNDIAVLYPPQRAPIVLVVMTSK -SERDAEYDNALVAEATRTT---- ->[subseq from] class A beta-lactamase n=1 Tax=Acidovorax sp. NB1 TaxID=1943571 RepID=UPI0010F8689B ---AWNDALATIERTAQGRLGVAMLDTGSGLAL-GWRQDERFAMASTFKAVLAGWMLALVD -QGKERLDHRLHYGRDAVIAHSPVSGPRAGDGLTVAELCAATVSLSDNTAANVLLAQHGGP -ASYTAFVRSLGDAATRLDRYEPHMAEAAAGDLRDTTTPQAMLQTLQKLVLGDVLTPVSRA -LLQRWLLETSTGDNRLRAGAP-GWKVGDKTGTGASGTANDIGVLWPAGGAPVLVTCYLTR -SAASPQQRDAAIAQVARAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium smegmatis TaxID=1772 RepID=UPI001303A696 ----VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAGRVLQGGE -RGELSLDDRVFVDPAALLPNSPITEEHAGGEMTLAELCQAALQRSDNAAANLLLKKIGGP -AEITAFARSIGDPRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQ -LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT -RGPNADGFRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=UPI000F6459DD ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALATPDRE -RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTARRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces vietnamensis TaxID=362257 RepID=A0A0B5HYG9_9ACTN ------ARLRRLEREHTARLGVFARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD -HDGEFLARRIHYTQAYVERVSPVAEKNVAGGMTVAELCDATIRFSDNTAGNLLLKELGGP -TAVTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPHDRA -RLTDWLLRNTTSTEKFRRGLPPEWLLADKTGSPRHGGANDAGIAWRPDGTPIVLSVLTTK -AEEDAPTDNPLVAATAALLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID685 TaxID=2690322 RepID=UPI001370A5B5 ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALATPDRE -RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTARRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. cf124 TaxID=1761903 RepID=A0A1I4UC19_9ACTN ----LSRQLGELEREYSARLGVYAHDPATGRTV-AHRADERFPICSVFKTLAAGAVLRDLD -RDGEYLAKRIHYTKEYVDAYNPITGTNVEAGMTVGELCSATVSHSDNGAGNLLLRELGGP -SAITRFCRSLGDRTTRLDRWEPQLNTAEPWRTTDTTTPRAIGRTYARLLLGRALRDADRE -LLTDWLIANSTNVQRFRAGLPADWTLADKTGGGTYGVANDVGVVWPPGRPPLVLSVLSTK -HDPAGPTDNPLVARAAGLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Herbidospora galbida TaxID=2575442 RepID=A0A4U3MBS3_9ACTN -----VAELRALETAYKGRIGVYAYDTATGNLI-TYRSGERFPFASTFKAVLAAAVLDKEP ----DILRKRIRYDQKDLQPHSPVTAKHVATGMTVAQLCEAAVTESDGTAANLLLRQIGGP -KGLTRYFRGLHDPVSRLDRPEPGLNDWSPTDPRDSTTPAAMGRDLHALTLGGALDAGDRE -RLTGWLVGNRTGDRRIRAGLPASWKVGDKTGTATYGATNDVAVVWPAKGKPIIMAIYARR -AGKNAAHDENVIAKTATIVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9012 TaxID=2184562 RepID=A0A3N8E0F0_9BURK ---AAQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPRDERDTSTPVEMVDTLQRLLLGDTLREPQRA -QLTEWMSGGARGATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2323.1 TaxID=1938841 RepID=A0A286HQ80_9ACTN --dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLAWPPGRSPIVMAVLTTK -REPDAAADNPLVAKTAALLAK-- ->[subseq from] Beta-lactamase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=A0A1G5H0N4_9DELT ----LENRIKEIEHALGARVGVSLYEVETSESW-SYKGDIRFPLMSTFKTLACAKTLLDVE -QKKVSFDDSVVIEKTSLITWSPVTKHHAGQAFSLKQACAAMMIMSDNTAANIVLDKTGGP -TALTAFMRSIGDAVTRLDRMEPELGEALEGDVRDTTTPNAMADSLHVLLFGDVLSKASKT -QLTQWMRSNKISGSLLRSVLPDGWTIADRSGAGGHGSRGITAVVWPETQPPFIVCVYLTQ -TKASFDERNKAIAEIGRELFKLy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. 92mfcol6.1 TaxID=1761901 RepID=A0A1W1H3F0_9GAMM ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVARRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus pantothenticus TaxID=1473 RepID=A0A0L0QTZ0_VIRPA ------EAFRLLEKEYDAKLGIYAMDTGTGKTV-SYRAENRFAYASTHKVLAVGVLLQKMN ---VNQLEETVLIKEDDLVNYNPITEKHVNKLMTWKELSDASMRYSDNTAANYILKRIGRP -AGFKQALRDIGDDVTKPERIEPELNKVKPGETRDTSTPKALATSLQTFTMGDVLTKQKQD -LLVNWLKRNTTGDNLIRAGVPEGWEVGDKSGAASYGTRNDIAIIWPPNEDPIILAVLSSR -DEEDAEGNDELIAKATEEVM--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 2323.1 TaxID=1938841 RepID=UPI000BB7C942 --dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLAWPPGRSPIVMAVLTTK -REPDAAADNPLVAKTAALLAK-- ->[subseq from] Beta-lactamase n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0I9QQ15_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLRSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUT7_9BACT ---NTERKLAELERKYDARIGVYAIDTGTNYTV-KYRPNERFAYASTYKAFAAAILLQKKS ---VEKMNEVIKYTEEDLVSYSPITEKYVNTGMTLFDLSEAAVRYSDNTAGNLILEALGGP -SGYERSLRKIGDTVTEVNRYEPDLNDFTPGDSRDTSTPKALATNLKKLALNRFLSDDKQT -IFFDWIKGNATGDALIRAGAPKDFVVGDKSGAASYGTRNDVAVVWRPNKEPIVIAIMSRY -NSEDAKYDDKLIEEAANITLKSf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK141 TaxID=2512171 RepID=A0A4R7GRC0_9ACTN --vDLGAEFGDLERRYGARLGVHARNLRTGRTV-AYRAGEPFAMCSTFKAFAAAAVLRDHG --DCASLDKLIHYPPRDILDNSRQSEAHLATGMTVGQACAAAIQYSDNTAGNLLLRQIGGP -QGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTSTPEALGRTFERLTLGRALARTDRE -QLVTWLKGNTTSVERFGAGLPRNWVLADKTGTGSYASANDVGVAWTTRQTPLLLTVLSTK -NAKDAPVDNRLIRDAAAILA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001123CF2A ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGNERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0002EB2DE2 ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGRTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093A2D06 ----ASADFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPALNDTAPGDSRDTSTPRALAVGLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -AEKDAKIDNKLLADATAAAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix carnea TaxID=1280637 RepID=UPI000D0DF184 ------DHLAGLERKFDARLGVYAVATGTGTTV-EHRADERFAFCSTFKGLAAAAVVARHP ---LSHLDTVVTYTEADLMASSAITRQHVATGMSVRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYLRTLGDTVTRADRFEPHLTTAVPGDPRDTTTPRAIGTDYREILLGDALPPDRRA -FLRDLLERNATGTLRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPDAAPLVVSIMSGK -ATADAEYDQALLAEAAAYVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium neworleansense TaxID=146018 RepID=UPI000B8A499E ----IDDQIAELERRHNALIGLYAVNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLENRVFVEPAAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDDRTRLDRWEVELNSAIPGDPRDTSTPAALAGGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSMRAGLPDGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAMMTRS -QADDADNLRPLIGELTAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D71FA ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDMLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DE2C53 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLFDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0003572F2F -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAP--------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007534D23 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVHGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2T1I906_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SVLTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1D8MAK3_ECOLX ----------------GARVGKIELDLNGGQILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRLLYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPYDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLRDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGADGKPSRIVLIYTTG -SQAT------------------- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium obuense TaxID=1807 RepID=A0A4R5X7C3_9MYCO ------DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDTFAMCSTFKAYASAAVLQRAQ -QGRLALTDAVLVGRSDIREHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP -SAITDFARSIGDDRTRLDRWETELNTAIPGDPRDTSTPRALGSGFRAVLTGDVLDGAHRQ -MLEDWMRANQT--SSMRAGLPGGWATADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS -ATPDADSLRPLIGEIAAAVA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111EBBAE ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDEPNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vietnamensis TaxID=362257 RepID=UPI000698422C ------ARLRRLEREHTARLGVFARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD -HDGEFLARRIHYTQAYVERVSPVAEKNVAGGMTVAELCDATIRFSDNTAGNLLLKELGGP -TAVTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDALEPHDRA -RLTDWLLRNTTSTEKFRRGLPPEWLLADKTGSPRHGGANDAGIAWRPDGTPIVLSVLTTK -AEEDAPTDNPLVAATAALLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2R3Q4E7_STEMA ------ADFAALEKASGGRLGVTVLDTGNGRRIgGHRQDERFPMCSTFKSMLVANVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGALTISDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000813B9F3 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVGSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QC07_STEMA ------ADFAALEKASGGRLGVTVLDTGNGRRIgGHRQDERFPMCSTFKSMLVANVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGALTISDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] serine hydrolase n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=UPI0012640C51 ------------AAESGVTLSVAVTDLAGGATV-TAGEDEQVKAASIIKLPLLAALMADVD -AGELDLDQAVTIPAGDIVGGSGTLKDQFPLDITVAELMELMVQVSDNTATNVLIDLAGGF -GAVNDYVAALGFEDLYLGRKMI--HPASPPLQENYISAEEVTELVTMLWEGEVLSAESSE -HIIDLMRGQLV-DTKFGAVIP-RVHLANKTGELAD-VSHDSGIVLLPGRE-LAITTTTSF -TDLPREEADVFVQETARVVYD-- ->[subseq from] serine hydrolase n=1 Tax=Georgenia satyanarayanai TaxID=860221 RepID=UPI0012640C51 --------------AQDVRVSVGFSDLGDGDRV-LLGSQEPYNPASVIKLSLLAAVMRQTE -RDLLHLDAPVTISPYMVVGGSGSFQDEMPFTTTVRELVRRMVVESDNTATNVLLYHI-GL -PTTQGLIDDLGLDVMRFNRQMFPG--ELIDEPANVLDVGDTLALLEAMYGDELLGEDSRE -QILTWMGDQEV-DTKFGAVLN-DAPVAHKTGETGN-VTHDVGYFLVPGHES-AVVVLTEV -TSETQEIGNPIVQEIGLAVYNY- ->[subseq from] class A beta-lactamase n=1 Tax=Cryocola sp. 340MFSha3.1 TaxID=1169145 RepID=UPI000362297C ---AAARALAELESQYGATIGVYAVDTGTGRSV-GYRQDDRFAYASTSKVLLAGAVLARSS ---DEQLDATVPYTSDDLVSYSPVTETMAGAGMPLRDVIAAALQKSDNTAANLLFRQLGGP -AELEKSLRALGDETTEVERTEPDLNEAAPGDPRDTSTPRALAADLRAYALGEELPANRRK -LLVDDMTGNATGDPLIRAGVPTGWTVSDKSGAASYGTRNDIAMLTAPGHAPVVMVVLSRK -AEKDAAYDNALVADTAKVL---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A1A0VYD7_MYCPR ----VDDQIAELEHRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RGQISLDNRVFVDPEALVPNSPVTETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYREILVGDALSPPQRR -QLQDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDPKADNPLIGELT------- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter glycinis TaxID=582702 RepID=A0A5B9E1C6_9GAMM ---AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD -RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKSVGGP -AAATRFVRSLDDDITRLDRHEPELN--VPDKGLDTTTPDAMLASMRKLLLGNVLSASSRA -QLIDWLRHNTTGETQLRAGMPASWQVGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG -PADQGDMRKAVLAHVGKLAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092B4FB1 ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSAKGKPTIAAAARIALRAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CF59B ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0006EBF9DF --------FSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIADATEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007599166 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. S23321 TaxID=335659 RepID=UPI0002562616 -------ELESYERDSGGRIGLYAENLATGAKL-SWRADERFVMCSTFKASLAACVLTRVD -RGEEQLAAMIPYGKADLLDYAPVAKQNLATGMSVAEMCKAIVELSDNTCANLLLTRIGGP -AALTTFWRSLGDATSRLDHNEPELNRSPPGNPHDTTTAAAMAGNLRRLVTGEALSPASRA -QLTEWMVGCKTGANRLRGGLPANWTIGDKTGNNGKDASGDIAVAWPKTGAPVLIAAYTQG -GTPTAAQIEAVFARIGRMVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=A0A0F0GVX0_LENAE ----ITGKLRELEKQHTARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRRDH --DGSLLGKVIRYTQEDVTKYGPVTGRNLANGMTVKSLCEAAITYSDNCAANLLLKELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRETDTTSPRAIGQSYARLTLGHALNRDDAD -QLTNWLLANTTGGNRIRAGLPAAWRWGDKTGTGRYSTTNDVGIAFPPGRAPIVIAVLSTK -KDPEGGADEPLVAKTAELVAASf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132ENU2_9BURK ---AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS -LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQAGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDRWEPELNAAAPGDERDTSTPVAMVDTLQRLLLGDLLREPQRA -QLIEWMVGGARGAAGIAAGVPPGWRVADKSGTGGYGTTTDVAVVWPPSRAPLVMAVSFTQ -PRADAAARADVVASAARIAAN-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00021E08F6 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSMARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDEDQRGAVLARVGAL----- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI0005F0BBE9 ---KLNEDLTAIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD -NEKLDKNATAKVEERNMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGTGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] carbenicillin-hydrolyzing class A beta-lactamase CARB-44 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0005426728 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNTLSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A6B6D1 ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora daliensis TaxID=295585 RepID=UPI0007824F5C ------ADLRALETSFKGRIGLYAIDTATGKTI-AYRSGERFPLASTFKAVLAAAVLDKKP ----DILGKRISIKKKDLVDYSPEVEKHVGSSMTVAALARAAVTKSDNAAANLLLKQVGGP -KGLTRYFRGLGDHVSRLDRTEPGLNRWSPRELRDTTTPAAVGRDLRDLAAGDALDAGDRR -IFTGWLVANETGDKRIRAGLPKSWRVGDKTGTGGYGTANDIAIIWPKGSKPIIMAIYTNR -TDRNAAADDSVVARTATIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000751EEF1 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. EAG2 TaxID=2056495 RepID=A0A2N3K2K5_9ACTN ---DAERRLARLERESGIRLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTQDDVERGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP -TAVTRFVRSLGDRVTRLDRFEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGLPEDWVLGDKTGAGHYGTNNDAGVTWPPGRPPIVLTVLSTQ -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075917CD ----AQLQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase OXY-2 (Beta-lactamase/transpeptidase-like, 38-293) n=1 Tax=Magnetospirillum sp. XM-1 TaxID=1663591 RepID=A0A0U5HXS6_9PROT ---RLAAPLAELEYHSGGRLGVMVKDVERGETA-GHRADERFALCSTGKVPTVAAALARHD -AEGGWLERQIPVAAADLVSWSPVVERRVGGVMTVAELCEAALTQSDNSAMNLLLRLLGGP -QAVTGYLRGLGDAETRLDRVEPELNEAALGDARDTTTPAAMLATLEKLMLGDALSPAGRA -RLVGWMAANRTGDRRLRASLPEGAWAAEKTGSGERGSTNDIGAFRLAGRGVVLIAAYLTD -TTLPANRRDLVIADVARTVV--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9X5A7_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMASSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG -ASVDDDQRAAVLARVGTL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075FBA1F ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGMPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. OULL4 TaxID=1904360 RepID=UPI000987D10E ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLALQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011211586 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDSYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. QGD 101 TaxID=1867256 RepID=UPI000C7F68BF ------ASVAALEPRHNALIGLYAVNLDTGRTV-ANRADEMFAMCSTFKTYAAARVLQMVG -RGQLSLDNRVFVDSAEIVANSPVTEARAGGEMTLAELCQAALQRSDNTAGNLLLKAIDGP -PGITAFARSIGDERTRLDRWETELNSAIPGDPRDTSTPAALATGYRALLVGDVLNPPQRR -LLEDWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAIMTRS -QANDAANLRPLIGEVTALV---- ->[subseq from] Beta-lactamase n=2 Tax=Roseovarius TaxID=74030 RepID=A0A5E7ZQQ4_9RHOB ---HLAATIDRIEQELDARVGVVIRESGSDWIV-SHRAEERFLMASTFKTMLCGAVLHRVD -EGDLDLEERIAIEAAEVLEYAPVTEKMVGETMSVGELCHAALDMSDNAATNLLIDRIEGP -QSVTAFLREIGDPVSRLDRREPDVNTFAPDDPRDTTTPEAMVSTMVTLLTGDALSPQSRA -QLVDWMSDGGVTGALIRASTPAGWHVADRSGSGNF-NRNIVAMVTPPDREPYFIAIFLSD -ADADFNTRNGAVIELSKAVMQ-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. TD3 TaxID=1641707 RepID=UPI0009534CC0 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAYVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDEDQRGAVLARVGAL----- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084A8BF8 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILERy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000927CFFA ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPASTKGKPTIAAATRIVLRAf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio jasicida TaxID=766224 RepID=UPI0005EE01B7 ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMINTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00088327BE ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVIASAARIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00112142C5 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSGSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. UM_WWY TaxID=1370121 RepID=UPI000407DD95 ----LDDQIAGLEKRNNASIGVFAANVDSNRTV-AHRADETFAMCSTFKGYAAGRVLQQVD -RGQLALDTRIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKLIDGP -PGITAFARSIGDNRTRLDRWETALNSAIPGDLRDTSTPAALGAGYRAMLTGDVLSPPQRQ -QLEDWMRGNET--SSMRAGLPVGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -RADDAANLRPLIGELTALVV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-495 TaxID=1609133 RepID=A0A0F4JE14_9ACTN ---ELADRLCALERLHSARLGVFAQDAATGRNV-AYRAHELFPMCSTFKTIAVAAVLRDLD -RDGTFLAERRHYTTRDVAEYAPITGLNLEAGMTVEELCSAAIRYSDNAAANLLLRELGDP -EAITHFCRSISDRVTRLDRWEPALNSAEPGRPTDTSSPHAIGRTYARLTLGKALDTADRQ -RLTRWLLTNTTGANRLHAGLPTTWTVAEKTGTGNYGTTNDVGVTWRPDGGPIVVSVLSTK -QIADAPADEPLIAETARLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852013-50091_SCH5140682 TaxID=1834109 RepID=A0A1A0XH03_9MYCO ----LDDQIAGLEKRNNALIGVFAANVDSNRTV-AHRADDTFAMCSTFKGYAAGRVLQQVD -RGQLALDTPIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKMIDGP -QGITAFARSIGDNRTRLDRWETELNSAIPGDLRDTSTPAALGSGYRAMLTGDVLSPPQRQ -QLEDWMRGNET--SSMRAGLPAGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -RADDAANLRPLIGELTALVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces monomycini TaxID=371720 RepID=UPI0004AA0E98 -hpAATRRLRELEREHQARIGVFALNLATGATL-LHRAHERFPMCSVFKGLAVAAVLRDLD -HDGTQLSRVIRYTEADVRKHVPVTSRHVADGMSVRDLCDAAVRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAVARTYRRLVLGNALDRPDRA -LLTDWLLRSTTSVERFRAGLPKDWKVADKSGGGSYGTSNDAGIAWTPDGTPIVLAAFTHK -PAPNASGDTPLIIKTATVM---- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium oceanosedimentum TaxID=465820 RepID=UPI0009E91529 ---ATSRAFAALEEQYGARVGVVAIDTADGGSL-GYRADERFAFASTNKAFIAAAVLDASS ---TDDLDDVVRYDRSDLLSYAPVTSQHVDEGMTVRALVDAALRESDNTAANLLVERLGGV -GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSATDLRAVLLGDALDPDDRA -LLRSATAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVEPPGRDPIVLVVFTTR -DGADAEPSDALVAAATRVAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FDFC48 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGSPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADAAPRADVVAEAARIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111D6328 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPAYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium smegmatis (strain MKD8) TaxID=1214915 RepID=A0A2U9PPQ0_MYCSE ----VDDRIADLERRNNASIGIYAVDLDSNRTV-AHRADDSFAMCSTFKAYLAARILRGAE -RGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLLLKQIGGP -AEITAFARSIGDQRTRLDRWEIELNSAVPGDPRDTSTPAALAGGFRAMLTGDVLGPPQRQ -LLDEWMRANET--SSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRT -RGPNADGFRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis flavescens TaxID=758803 RepID=A0A1M6BSI5_9ACTN ----VSAELAALEEEFDAHLGVYAVDTGTGAEI-AHNADDRFAYASTHKALSAGAILERNT ---LEEMEEVVTFTEDDLVGWTPVTEQHVDTGMTLLEVIDAAVRHSDNTAANLALEELGGP -QGFEDALRGIGDEVIEAERWEPDLSEHTPGEERDTSTPRAMAASLEAYTLGDVLPEEKQD -VLIDLLLRNTTGDATIRAGVPEGWTVGDKTGSANYGTRNNIALLWPAEGEPIVLAIMSSR -DEEDAERRDELIAETAGVVAD-- ->[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI000BA7B6B3 ------AVFKALEEEYAARLGVFALDTGTGQTV-SYRSDERFTYASAHKPLAVAVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANFIFDEIGGP -EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFALGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWEVGDKTGAGSYGTRNDIAILLPPEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075EF64B ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. GW247-27LB TaxID=2012632 RepID=A0A270BFB3_9SPHN -----AGRLAALEKQSGGRLGVAFLDPASGRTT-GHRADERFALCSTFKWPLSAVVLKAID -EGKLTLDRRVPYGKADLLPNSPVTQKNVAKGMTVAELMEATITASDNAAANLLLPLVGGP -EAVTRQFRAWGDPVTRLDRAEPHLNLVGEGEVRDTTTPAAMTALLRTTLLGDALSPASRT -RLIDWGVATTTGPQRLRAGLPAGWRIGHKTGTAMMNKYNDIAIAFPPKGAPLLIAAYYEG -PVATRDADQAVLAAVGRLAAE-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011224BE2 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPDDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DDB873 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAGLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis eurytherma TaxID=196083 RepID=A0A3N2GQT5_9PSEU ------VDFAGLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVTYTDADIQPNSPVTKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP -AGLAAVLREIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGDALPADKRD -LLVGIMRRNKTGTELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPGRAPIVLALMSSR -TAADASYDNKLLAEATSRVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium oceanosedimentum TaxID=465820 RepID=UPI000736EB58 ---ATSRAFAALEEQYGARVGVVAIDTADGGSL-GYRADERFAFASTNKAFIAAAVLDASS ---TDDLDDVVRYDRSDLLSYAPVTSQHVDEGMTVRALVDAALRESDNTAANLLVERLGGV -GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSATDLRAVLLGDALDPDDRA -LLRSATAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVEPPGRDPIVLVVFTTR -DGADAEPSDALVAAATRVAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00031EE049 ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKATIAAAARIVLRAf ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. BK308 TaxID=2512170 RepID=A0A4R3CN52_9ACTN ---ALEGELRDLEKRYAARLGVYARNLRTGQVV-AHRARERFALCSTFKAFAAAAILRDHG --HCAPLDRVIHYPPADVVLNCPVTGKHVDTGMTVGDLCAAAIQYSDNAAGNLLLRQIGGP -EGLTRFFRSIGDPVSRLDRWETELNSAVPGDLRDTTTPEAVGGGFTRLTLGRSLADADRE -QLVTWLKGNTTSGERFRRGLPRNWVVADKTGTGDYATGNDLGVAWTGRGTPVVLAVLSSK -STRDAAVDNGLIADTARLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium elkanii TaxID=29448 RepID=A0A0D1LM52_BRAEL ---SIEHRLKDVEVQSRGWLGVALLDTATGKLI-GNRIDQRFAMCSTFKALAVALVLARVD -RGEEQLDRRVVFSEHDLVPPSVATQPHVGPGMTVAELCEAAVTVSDSTAANLLLASFGGP -AALTAYLRSLGDPVTRLDRVELDLNIVKPGEQHDTTSPAAMARTLQRLLLGDALSEPSRA -RLTGWMAGAKDATTRLRAGLPQGWRIANKPGTWKGIATNDVGVIWPPGRAPIVVAAYLAD -APTPVATQEAILAEIGRIVAE-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI0003A4CA22 ---KLNEDLAAIEQHIGGRIGVSVWDTQNDQHW-DYRGDERFPMMSTFKTLACATMLNDMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QD19_STEMA ------ADFAALEKASGGRLGVTVLDTGNGRRIgGHRQDERFPMCSTFKSMLVANVLSLAD -AGRVSLDTRVSIAGKDLLSYAPVARRHVGKDLTVRDLCRGALTISDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMAASLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces hyaluromycini TaxID=1377993 RepID=UPI000B5CED6F -----TARLRALEREHRARLGVFAWDTGSGARL-GYRSGERFPMCSVFKTLAVAAVLRDLD ---EGVLTEVVHYDEGDVERGAPVTGRNLAAGMTVEELCAAAVSYSDNAAANLLLEQLGGP -VAVTRLCRSLGERVTRLDRWEPELNSAEPGRVTDTTTPSAVATTYVRLTVGHALDGADRR -RLTGWLLANTTGGERIRAGLPADWRVGDKTGTGGHGTANDVAVAWPPGRAPVVVAVLSTH -ADAAAEPDSPLVRAAATVVADTf ->[subseq from] UPI000FF87531 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FF87531 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCATFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075V3A2_9PSEU ----ASTDFEQLERTFGARLGVYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---VAELDRTVTYGQQDLVTNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPALNDTAPGDSRDTSTPRALAVGLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -AEKDAKIDNKLLADATAAAIK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Kitasatospora sp. Root187 TaxID=1736486 RepID=A0A0Q8P8R3_9ACTN ----ITSRLRELEQQHSARLGVFARNMRTGRTV-AYRADERFPMCSLFKTVAVAAVLRDLD -HDGEFLAKRIRYTAEYVKKYSPRTGRNLESGMTVAQLCDAAICYSDNTAGNLLLRELGGP -TALTRFCRSIGNGRTRLDRWEPELNSAEPSRVTDTTTPRAIGRTYAHLTLGDALTPQDRE -RLTGWLLANTTSGERFRAGLPGDWILADKTGGGRYGGNNDAGVTWPPDGGPIVMAVLTTK -HVEDAPADHPLVARTAAMLA--- ->[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=2 Tax=Mycobacteroides abscessus TaxID=36809 RepID=X8DQA0_9MYCO ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007573065 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRLRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE7681 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00092C1143 -----------------------------------------FPMCSTSKVMAVAAVLKQSE -TQKQLLNQPFEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNRAGAASIRAGLPTSWTVGDKTGSGDYGTSNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005DD9877 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPASTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis australiensis TaxID=546364 RepID=A0A1K1SAS7_9PSEU -------DFAPLEHDFDARLGLYAVDTGSGREV-AHRADERFGYASTHKAFSSAAVLQRTG ---LDGLAKILNYTRTDLQPNSPVTEQHVTTGISLRDAIDAALRYSDNTAANLLFRELGGP -PGLAAALRGVGDTTTHVDRVEPGLNDLAPGDVRDTSTPRAMARGLRAFTLGDALPPEKRQ -VLTDTMRANTTGAALIRAGAPAGWAVADKTGTGGYATRDDIAVVWPPGRAPIVLVVMSDR -KTQDAPHDDRLIAEAAKLAF--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001124B06C ---KLNEDISLIEKQTSGRIGVSVWDTQKDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Bla protein n=1 Tax=Burkholderia sp. MSHR3999 TaxID=1542965 RepID=A0A0D0GFC5_9BURK ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVVWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI000DFA4D40 ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADSLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus kochii TaxID=859143 RepID=A0A248TH22_9BACI -------KFAQLEEKYGAKLGVYAIDTGNEETV-AYQEDERFAYASTFKALAGAVLLKENP ---ISILDEKRMYTKEDLVTYSPITEKYVDEGMTLREIAKAAMQYSDNTAGNLLFAELGGP -DQLEEALRAIGDDVTEMDRLETELNEATPGDTRDTSTPKALATNLRIVGLTDELSEEKRE -IFQEWFKGNTTGDTLIKSGVPTDWIVGDKSGAASYGTRNDIAIVWPPNDEPIVIAILSNK -QEKEAEYDDQLIGEATEIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium chitae TaxID=1792 RepID=A0A448I6C8_MYCCI --------LAGLEDRYGARIGMTAVDLASGKSL-AHRADQRFAMCSTFKTYAAARVLQLTE -QGRLHLDTQTPITESDIVTHAPVTGTKVGQSMSLADLCAAALMESDNTAGNLLLRAIGGP -PAITEFARSVGDDRTRLDRWETELNSALPGDPRDTTTPGALALGYREVLTGTALAEASRE -QLLAWMKANITSDKRFRAGLPAGWTSADKTGGGDYGTTNDAGLLLGPKGQRIVLVVLTRS -LDPEAGPYNEAIAETVR------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium madagascariense TaxID=212765 RepID=UPI00138D7D5F ---RAQDALAQLEARARVRLGVFALDTATQAST-GYRADERFLLCSTGKVLDVAAILKRSE -TDPGLLDRVITYGPSDVLAYAPVTSQHVTDGMTVAALCDAAITVSDNTAANLLVELLGGP -PAVTAFARGIGDGVTRVDRLEPDLNVTTPGDPRDTSTPRQMALDLQTLVLGDGLADDSRQ -RLTDLLKANTTGAQTIRAGLPSDWVVGDKTGSGAQGEGNDVAVAWPPNRPPLLIAIYVAP -VDLAADDVHRVIAEAARIA---- ->[subseq from] Beta-lactamase n=1 Tax=Plantactinospora sp. BB1 TaxID=2071627 RepID=A0A2R4FT08_9ACTN -----HDQLLRLEREFDARLGVYALATGTGTVV-AHRADERFAFCSTFKGLAAAAVLARNP ---LTHLDTVVRYARRDLTANAVITRRHVDRGMTIRQLCDAAVRYSDGTAGNLLVRDLGGP -AQLTAYARSLGDTVTRMDRIEPAITQATPGDPRDTTSPRAIGTDYQKILLGDALVPEKRA -FLRDLLERNATGARRIRAGVPKGWTVADKTGTGGYGTVNDIGVVWPPNSPPLVIAIMSSR -AARDADHDQAIIARATEYAV--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. DAIF1 TaxID=2546450 RepID=UPI0010710114 ----AAADFAALEKACRGRLGVTLLDSAGGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLMLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDMAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=A0A1W0ARC9_9NOCA -----HARLAELERDYGARLGVYALATGTGDII-DYRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVHYTEADLLKNATITPGHVAEGMTIRALCDAAIRYSDGTAGNLLLRDLGGP -SELTAYARSLGDTVTRMDRVEPDITEATPGDPRDTTSPRAFGTDYQHIVLGEALAPEKRA -FLRDLLERNATGARRIRAGLPRGWVVADKTGTGDYGTLNDIAIVRPPDSAPLVIAIMSSK -ATVDAAYEPALLAEAAEYVA--- ->[subseq from] BCL family class A beta-lactamase n=1 Tax=Bacillus clausii TaxID=79880 RepID=UPI0009ED85A6 ------AVFKALEEEYAARLGVFALDTGTGETV-SYRADERFTYASAHKPLAVGVLLQQKS ---IEELEQLITYSADDLVNYNPITENHVETGMTLRELSDASIRYSDNTAANLIFHEIGGP -EGFKEGLRAIGDTVTEPERIEPELNHVEPGEIQDTSTPEALAKSLQEFTLGEALPADKQE -LLIDWLIGNTTGDALIRAGVPEGWDVGDKTGAGSYGTRNDIAILWPLEKEPIILAVLSSK -DEKDAEYDDELIAKATEEVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115BFE30 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGCR---------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBW8_STEMA -----ATDFAALEKACAGRLGVTLLDTASGRRF-GHRQDERFPMCSTFKSMLAATVLSQAE -RTPALLGTRVPVRDADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDAVSRSDRLEPELNSFAEGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPLGGTPCRVNAYLQA -SAISYEQQAVVLAQVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoplanes sp. N902-109 TaxID=649831 RepID=UPI00059F7D06 -----QRAFAALESQFDARLGVYALDVKSGHAV-AYRADERFAYASTYKALAAGALLAHTS ---DADLDDMVTYQRADLVAHSPVTGKKLADGISIGDAAEAAVRVSDNTAANLVLRELGGP -AGWEKDLRGVGDTVTEAARTEPELNAATPGDKRDTSTPRALAADLRAYVLDDALDAGDRS -TLTRWMTGNATGNTLIRAGVPKGWTVADKSGGGQYGTRNDIAVVWPEPDRPLVLAVLSSR -AGADADYDDALIARAASVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0003166A66 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDLTSTKGKPTIAAATRIVLRAf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI000CE529B3 ---KLNEDLTAIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD -NEKLDKNATAKVEERSMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGTGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aurum TaxID=1791 RepID=A0A448INC5_MYCAU ---AIDERIAALGRRHNAQIGLYAVDLNTQNSL-SYRDTERLAMCSTFKAYAAAAILQRAQ -RGQLTLNDPVAIEAGDIRPHSPVTEPRVGTTMTVAELCQAAVQQSDNAAANGLLGVLGGP -QAITEFARSIGDDQTRLDRWEIELNTAIPGDPRDTSTPRALGSGYRAVLTGDVLAPAGRQ -QLVDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRVLLAIMTRS -ATPDAPSLRPLIGEVASLVLA-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio owensii TaxID=696485 RepID=UPI0005EF10DD ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDTLSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] UPI000FF874C9 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI000FF874C9 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCCTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075DDB26 ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVAAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLRELQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces globisporus TaxID=1908 RepID=UPI0004CA9F39 ------ARLRRLEREHTARLGVFARDMRTGRTV-AHRADERFPMASVFKTLAVAAVLRDLD -HDGEFLARRVRYTEAYVARHSPVTGSNVSGGMTVSGLCDAALRFSDNTAANLLLERLGGP -AGVTRFCRSTGDRVTRLDRWEPELNSAEPWRVTDTTTPYAIGLGYARLVLGDALEPHDRE -RLTGWLLRNTTSTERFRRGLPADWLLADKTGSGRYGGAGDVGIAWRPDGTPIVLAVLTTR -PEEDAPADNPLVAGTATLLAE-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000CE94695 --sQLNEDIALIEQQTSSRVGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Beta-lactamase 2 n=1 Tax=Streptomyces cacaoi TaxID=1898 RepID=BLA2_STRCI -----AAELKALEDEFDVRLGVYAVDTGSGREV-AYRDGERFPYNSTFKALECGAVLDKHT ---DREMDRVVKYSEDDLVDNSPVTEKHVEDGMTLTALCDAAVRYSDNTAANLLFETVGGP -KGLDKTLEGLGDHVTRMERVEPFLSRWEPGSKRDTSTPRAFAKDLRAYVLGDVLAEGDRK -QLTTWLRNNTTGDGLIRAGVRQGWVVGDKTGTGSYGARNDMAVVWRPDGRPLVLNVMVHG -HTKDAELDSELIARATEVVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A105ZJQ6_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNLARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. RV163 TaxID=1661388 RepID=UPI00069EC0AD --------FALLAEEFGVRLGVYAVDTGTGREV-GFHADERFAYCSTFKVLAFGAVLDRTP ---VEALDRVVTFSEADLVFHSPVTHEHVASGMTLRGIGDAALRHSDNTASNLLVEELGGP -PELEKALRGIGDDVTNVDRLAPEMAEAVPGDVRDTSTPRAMAASLRAFALGDVLTEERRE -VLVGMMRANTTGDGLIRAGVPEGWDVGDKTGACGYGTRHDIGVLWPPGGAPLVLAVMSSR -DEAGAGYDDALIARATQTALE-- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea albida TaxID=65499 RepID=A0A1H9PF51_9PSEU ----ITGRLRELERQHHARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRKDR --DGTLLGKVITYTKSDVDKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLKELGGP -TAISRFCRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD -QLTKWLLANTTGDNRLRAGLPAAWRWGDKTGTGSYGTTNDVGIAFPVGRAPIVIAVLSTR -ESPTGGADEPLLAKTAELVAATf ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. SLBN-118 TaxID=435993 RepID=A0A542QJD1_9ACTN ----ISGALSNLEREHSARLGVFARNTVTGRSV-LHRADELFPVCSVFKTIAAAAVLRDLD -RRGEFLAKRIRYTDKDVKDYGPITGEHLAGGMTVAELCAATIEYSDNAAANLLLHELGGP -TAITCFCRSIGDTTTRLDRFEPKLNSAEPWRVTDTTSPCAIGRTYEKLVLGDALTRPDRQ -QLTAWLLANTTSGARFRAGLPKDWTLADKTGTGEYGTTNDVGVAWTPDGAPVVLAVLSTK -HDAHCPADEPLVAKTAELLT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium subroseum TaxID=106412 RepID=A0A239NDI5_9ACTN ---EARRQLRALEASFKGRIGAYALDTATGKTV-TYRSGERFPLLSTFKASAAAAVLHKAR -TDPGLMDRVIHWKKSEVKANSPVTEKHVKDGLSVARLCEAAITQSDNTAGNMLLKQIGGP -AGLTRYFRTLKDPVSRLDRWETELNEWTPKEKRDITTPAAMGRNLRGLATGAALNAKDRA -RLNGWLRANKTGDERIRAGLPATWTIGDKTGTTSYGAANDIAVVWPGKGAPLIMAIYTNR -RAAGALSDNKVIADTAAILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758CEC3 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075DFAD6 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=UPI0002D1F93F ----YNSEFSKIESDYGVKLGVYAYDTEKNKEI-TYNADERFAYCSTSKALLAGSILEKYP ---VDKLKEVIQYEEKDLLSYAPVTKDNLNKGMTIEELCEAAVRLSDNTAANLLFNLIGGP -SGFKESLNKLGDNVTEPERIEPELNSAIPGEIRDTSTPRQLALDLKEYISGNILTDDKKA -IFIDWMSGNSTGDNLIRAGAPNEWIVADKSGAGDYGTRNDIAIVTPPNGKPIFLAILSNK -NEEDAKYDDETIAEASKVVFDYf ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI001375B6DA ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKTTRLDRLEPHLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000471E1A0 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKQDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D5496 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9C9EA1 ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TDADFAQRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 844.5 TaxID=2485140 RepID=A0A3N1KU34_9ACTN ----IDGRLRALERKHSARLGVFAYDTGTGRVI-RYRADELFPMCSTFKTIAVAAVLRDLD -CDGRFLAEVLHYTEEYVTQYAPITALNVADGMTVADLCAAAIDHSDNGAAKLLLRELGGP -SAVTRFCRSLGDRVTRLDRWEPELNSAEPGRITDTTSPHAIGRTYARLVLGDVLAAPDRH -RLTGWLLADTTSGNRFRAGLPQDWTLADKTGTGDYGTTNDVGITWPPGRKPIVMAVLSTT -LSPAAPADEPLLAETATLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Plantactinospora sp. BC1 TaxID=2108470 RepID=UPI000D151BA2 -----HDQLLRLEREFDARLGVYALATGTGTVV-AHRADERFAFCSTFKGLAAAAVLARNP ---LTHLDTVVRYARRDLTANAVITRRHVDRGMTIRQLCDAAVRYSDGTAGNLLVRDLGGP -AQLTAYARSLGDTVTRMDRIEPAITQATPGDPRDTTSPRAIGTDYQKILLGDALVPEKRA -FLRDLLERNATGARRIRAGVPKGWTVADKTGTGGYGTVNDIGVVWPPNSPPLVIAIMSSR -AARDADHDQAIIARATEYAV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus lehensis G1 TaxID=1246626 RepID=A0A060LZ65_9BACI ------AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAIGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIADATEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia pseudovaccinii TaxID=189540 RepID=UPI0007A376B3 -------QLAGIEQQHQARLGVFAVDTGSGRTV-GFRQDERFAMMSTFKTLACAALLHEHP -LATGYFDQIIHFTEADAAAGSAVTGTRIDSGMSVSELCDAAITRSDNAAGNELLKLLGGP -QALTRFLRSIGDQISRLDRTEPTLNTAIPGDERDTTTPAAIAADYRALTVGDALAAPERE -QLTAWLIATTTGGARIRAGLPNDWKTGDKTGTGDYGSANDVAVTWPVGSAPIVIAVLTTH -SSPDAQADNALVAEATEEA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 455mf TaxID=1761812 RepID=A0A1I2IFC4_9MYCO ----VDDQIAELERRDNALIGLYAANLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDADNLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia vinacea TaxID=96468 RepID=UPI0005946BFF -------QLAGIEQQHQARLGVFAVDTGSGRTV-GFRQDERFAMMSTFKTLACAALLHEHP -LATGYFDQIIHFTAADAAAGSAVTGTRIDSGMSVSQLCDAAITRSDNAAGNELLKLLGGP -QALTRFLRSIGDQVSRLDRTEPTLNTAIPGDERDTTTPAAIAADYRALTVGDALAAPERE -QLTAWLIATTTGAARIRAGLPNEWKTGDKTGTGDYGSANDVAVTWPAGSAPIVIAVLTTH -SSPDAQVDNALVAEATKE----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. T44 TaxID=2686304 RepID=UPI001317F651 ----TDGEFSELERRHGARIGVFARNLRTGLTV-AHRAGERFAMCSTFKAFAAAAVLRDHG --DCAPLGAVIHYPPHDILSNSPRTAEHVDTGMTIADLCAAAIQYSDNTAGNLLLRQIGGP -AGLTRFFRSLGDEVSRLDRWETDLSSAIPGDLRDTTTPGALGRSFERLTLGRALTGGDRA -RLVGWLKGNTTSAARFGAGLPRDWVLADKTGTGDYGTANDTGVAWTTRETPLLLTVLSAK -TAQDASADDALVAQAARILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus lehensis TaxID=300825 RepID=UPI00056DB11E ------AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAIGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIADATEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia brasiliensis ATCC 700358 TaxID=1133849 RepID=K0EP12_9NOCA ----RHDRLSELERKFDARLGVYALDTASGAII-AHRAEERFAFCSTFKGLAAAAMLQRNP ---LSHLDTVVRYTEADLTKNAAITPQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTAYLRGLGDPVTRMDRIEPAITEATPGDPRDTSSPRALGTDYQRIVLGDALPDDKRA -FLRDLLERNATGAGRVRAGVPQGWKVADKTGTGDFGTLNDIAIVWPPDRAPLVISLMSSK -ATADAEYDQALLAEAAAYVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces viridochromogenes TaxID=1938 RepID=UPI0005663D8F ---------RSLEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG ---TDGLDRVVRYSRDDLVADSPVSENFVKTGMSLRGLCAATLWYSDNTAVNLLFDELGGP -DGLEKVLEEFGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKADERE -LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVMSSR -DKQGAERDDALLAKAAAVAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A428Z6B3_KIBAR -------DFKALEARFDARLGVYAVDVTTGKSV-AHRENERFAICSVFKAYAAGALLKAHP -LSSGFFTQTIRFTQAEVVANSPVTGARVATGMTVAELCEAAITKSDNTAGNQMLKLLGGP -TKLTDFARSIGDPVTRLDRWETELNVVPRGTEQDTTTPSAIANAYRGLVVGDILAEPERK -QLKDWLIANTTGDARIRAGLPKGWVTGDKTGTGSFAAANDVAVTWPSPEKPIVIAILTDK -ADENAKYDNALIAEATKAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. KBS0801 TaxID=1179675 RepID=UPI00110E2A6A ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREAQRA -QLTEWMTGGARGATAIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=A0A3R8QCH6_9ACTN ------GELADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALATPDRE -RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTARRTPVVLAVLSTK -EGKNAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0004E98156 ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFAAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Tatumella sp. UCD-D_suzukii TaxID=1408192 RepID=UPI000472D6AF -------QAKLAEQQLHARVGFAELDLATGALReSYRSGERFPMMSTYKVLLCGAVLARID -SGREQPERRIMYRQQDLEKYSPVTKQYLNEGMTIAGLCDAAITMSDNTAANLLLSSIGGP -QALTRFLRQTGDPMTRLDRQEPELNEALPGDPRDTTTPEAMARTLRNLLSGKILTAASQQ -QLLHWMIADQVAGPLLRKVLPAGWFIADKSGAGEHGSRGIIAVTGPAGKPSHIVVIYITD -NDASMDVLNRQIAGIGAAMF--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066BB1FE ------ADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -SGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0I9QQ20_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNHGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium houstonense TaxID=146021 RepID=UPI00082AD4FC ----IDDQIAELERRHHALIGLYAANLDTGRTL-THRPDDMFAMCSTFKGYAAARVLQMVG -RGQLSLDQRMFVDRAAIVPNSPVTEAHVGSEMTLDQLCQAALQRSDNTAANLLLKNIDGP -AGITAFARSIGDERTRLDRWEVALNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRR -QLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGVAYGPDGQRLLLVMMTRS -QA-DDPKADNL------------ ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf100 TaxID=1736252 RepID=UPI000700239C ----ATNTLREIERRVGGRLGVSVGKSNAPPLL-GHRADERFPMCSTFKVLAAAALMARVD -AGTESLDRALPYGEGDLLKYAPVTRKALEAAISVADACAAAVEWSDNTAANLMLNVLGGP -SALTGWLRGIGDPTTRLDRTEPDLNTAIPDDPRDTTTPDAMRTTLEQILVGTALSPATRT -RLDGWLAAGRTGSKRLRAGIPPDWKVGDKTGSGDNGTYNDVAILRPPGQAPILAAVYLTG -STAPVTDVDAAYAEIGRMIAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9G8_SHISO -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A85931 ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KJ53_9PSEU -----RADFEQLERAFGARLGLYAVDTATGREV-AFRADERFAYASTHKAFSAGGVLQRTP ---IADLGRTVTYRAQDLVSNSPVTEKHVDTGMPLRDVIDATLRYSDNTGGNLLFRELGGP -AGLGAVLRGIGDTTSHVDRIEPELNDTAPGDIRDTSTPRALAVSLRAFALGNALPEDKRK -ILVDIMRANTTGDTNIRAGVP-GWPVADKTGTASYGTRNDIGVIWPPNRAPIVLSVLTDR -ATKDAGIDNKLLAQATAVAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI00099456AD ------SEIASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRSL -SEPGLLDKRIHYTQSDIMEWAPVASQHLAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEEELN--VPDGDLDTSSPLQLVTNLRRLVLDEGLDSQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Kosakonia radicincitans TaxID=283686 RepID=UPI0005C31B16 ---RLAEAVRLQEQQLGARIGVAVVDTASGETA-SYRGDERFPLNSTHKALLCGALLSQVD -KGELALTDTTQFPRSALVAYSPVTEKFVAPAISWQQLCSAAVSYSDNTAANLLAQKLGGP -LSITRYLQTLGDSVTQMDRFEPELNSAIPGDLRDTTTPLAVSHTLQKLTLGTALQPGSRA -QLIQWMRDDKVADTLLRSTLPDGWSIADKTGAGDFGSRSIISVVWPQNSSPRIVVIYITN -TKATLKQSNAAIASLGKTIF--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000A3A6AAA ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYATD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. CC22-02 TaxID=1378087 RepID=A0A4R7UL05_9GAMM ------ADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLDVVGGP -PALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHAGPAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075965CC ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEV3_9BACT ----LTREVAQEESTLQARIGVAVIDTGSGLIW-QHRGEERFPLNSTHKAFACAAVLAQAD -NNKVSMDMPIPINRDALVTYSPVTGKVPSGGQSLRELCRAAVSVSDNTAANLALNAIGGP -PSFTTFMRSMGDNETHLDRLEPELNEANPGDARDSTTPLAAARSLQKLLLGDVLSTTART -ELTQWMLDDQVADTLLRAGIPKDWRIADKSGAGGHGSRSIIAVIWPPERSAVVIAIYITQ -TTASMSASNQAVSRIGSALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium brachiatum TaxID=269660 RepID=A0A3G2VBU0_9RHIZ --eAVESALAAIEKRLGGRLGVSAGT-PERVFL-RHRADELFPMCSTFKVLAAACVLARVD -AGTESLDRLVTYGNDVLLSYAPVIRKGLEAGMTVADLCAAALEWSDNSAANLLLAALGGP -EALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAAARA -RLEAWMVASQTGFKRLRAGLPPDWTVGDKTGTGDNGTVNDVAILRPPGRAPILACVYVTG -AQAPTEVVEAAHAEIGRLVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0S1LJ16_ECOLX ---------------------------------------ERFPMMSTFKVVLCGAVLARVD -AGDEQLQRKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0002F6793C ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIALRAf ->[subseq from] Beta-lactamase (Penicillinase) n=1 Tax=Mycobacteroides abscessus subsp. bolletii TaxID=319705 RepID=A0A1N1AIR0_9MYCO ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIALRAf ->[subseq from] class A beta-lactamase n=1 Tax=Niveispirillum sp. SYP-B3756 TaxID=2662178 RepID=UPI001291A19B ----MRKDIEALERARGGRLGVAVLDTASGRAM-DWRGDERFAMCSTFKFLLAGHVLALVD -AGRERLDRTLPVPPKKLLDWSPATEPHAGGSLDIAALCHGIITRSDNTGANMLLDATGGP -EALTAWLRQLGDTITRCDRPEPAANLVPPGEVRDTTTPISMLGLMRTLLLGNALSAPSRK -QLTDWLIANTTGDNRLRAGLPAGWKVGDKTGSWDD-ATNDIAIVWPKGAAPLLITSYYRN -ADLDSKGRNAVLAEVGRIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0002DD26FC ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIALRAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005E7A73C ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIALRAf ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4YFB8_9PSEU --------FADLERRYDARLGLFAVNVHTGRSM-GYRADERFAMCSTFKTYAAGALLHRHG -LAGGYFDKLIHYTEADLVAGSPVTAPNAGIGLMVNELCAAAITRSDNTAGNLLLAELGGP -SAITAFARSIGDGSTRLDRWETELNTAIPGDERDTTTPAGIAAGYRALVVGDALGAPERD -RLAGWLFANTTGAARIRAGLPPAWRTGDKTGTGDYASGNDVAVTWTDRGQAIVIAVLTTR -PRKDDEVDNGLHADTARVVAA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 120-Carrot TaxID=678949 RepID=D7PIH1_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARKLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F2D1D ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A92B8 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVAEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Erwinia mediterraneensis TaxID=2161819 RepID=UPI001031A895 --------VLQEEKALKARIGVAVMDTASGQTL-SYRGHERFPLNSTHKPLLCGLLLSKVD -AGELSLTDSIRFKKETLVDYSPVTEKFVAPRMNWQEVCQAAVAYSDNTAANLIAKSVGGP -PAVNHFLAAIGDNITRSDRFEPELNTSQPGDLRDTTTPVAISQTLYALTLGKVLQPASRQ -QLLQWMFDDKVADALLRSVLPPHWKIADKSGAGAYGSRSIISVVWPEKREPLIVVVYITQ -TEATMAQSNAAIARIGKTIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus sp. BO TaxID=1476855 RepID=UPI000BA4AC23 ------AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALTVGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIAEATEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000754C9B4 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi (strain 1DA3) TaxID=673519 RepID=D0X6B6_VIBH1 ---KLNEDLASIEEHISGRLGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPGDKQDTTTPNTMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus miscanthi TaxID=2598861 RepID=UPI0011A0444B -----AATFSVLEDHYDARLGVYAFDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEATEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIAEATEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075261EC ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAVPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces koyangensis TaxID=188770 RepID=A0A385DC27_9ACTN ---DAERRLARLERESGIRLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTQDDVERGAPETGKNLANGMTVEELCKVSITASDNCAANLTLRELGGP -NAVTRFVRSLGDRVTRLDRFEPELNSAEPGRVTDTTSPRAITRTYGRLVLGDALNPRDRR -LLTSWLLANTTSGDRFRAGVPEDWVLGDKTGAGHYGTNNDAGVTWPPGRPPIVLTVLSTQ -TEQDAVRDDGLVADAARVLAE-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI0003A2BA26 ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPDDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rochei TaxID=1928 RepID=A0A510DF97_STRRO -------ALADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEGNQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALTAPDRE -RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0010E7CFA1 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSNSLMRSVLPKGWSIADRSGAGNYGSHGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. SC-N050 TaxID=1896671 RepID=UPI0008B386D8 ------ADFAELEKASGGRLGVTVLDSRTGRRIgGHRQGERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVAVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP -AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLALFAVGDGISAASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lasaliensis TaxID=324833 RepID=A0A4U5WBE4_STRLS ---DLSEEFRALEQSYGARLGVYARNVRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHG --HCAPLDRVIHYPPRDILDNSQHSEDHLATGLTVGQACAAAIQYSDNTAGNLLLRQIGGP -QGLTRFFRSLGDRVSRLDRWETDLNTAVPGDLQDTSTPQALGTSFERLTLGRALARTDRE -QLVTWLKGNTTSAQRFGAGLPQDWTLADKTGTGSYATAHDIGIAWTTRRTPLLLTVLSTK -DAGDAPVDNGLIRDAAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Tatumella ptyseos TaxID=82987 RepID=A0A085JH61_9GAMM -------QAKLAEQQLHARAGFAELDLATGALReSYRSGERFPMMSTYKVLLCGAVLARID -SGREQPERRIMYRQQDLEKYSPVTKQHLNEGMTIAGLCDAAITMSDNTAANLLLSSIGGP -QALTRFLRQTGDPMTRLDRQEPELNEALPGDPRDTTTPEAMARTLRNLLSGKILTAASQQ -QLLHWMIADQVAGPLLRKVLPAGWFIADKSGAGEHGSRGIIAVTGPAGKPSHIVVIYITD -NDASMDVLNRQIAGIGAAMF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru71 TaxID=2080746 RepID=A0A2S4Z4V9_9ACTN ---DLDAELGRLEQRYGARLGVYARNVRTRRTV-AYRAGEPFAMCSTFKAFAAAAVLRDHG --DCAPLDKVIHYPPRDILSNSQHSEDHLATGMTVGEACAAAIQYSDNTAGNLLLRQVGGP -QGLTRFFRSLGDKVSRLDRWETDLNAAVPGDPQDTSTPEALGKSFERLTLGRALARPDRE -RLVTWLKGNTTSAERFGAGLPRDWVLADKTGTGSYATANDIGVAWTTRQTPLLLTVLSTK -DAKDAPVDNRLIRDAAAVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=UPI0009FEB160 -----RADFEQLERAFGARLGLYAVDTATGREV-AFRADERFAYASTHKAFSAGGVLQRTP ---IADLGRTVTYRAQDLVSNSPVTEKHVDTGMPLRDVIDATLRYSDNTGGNLLFRELGGP -AGLGAVLRGIGDTTSHVDRIEPELNDTAPGDIRDTSTPRALAVSLRAFALGNALPEDKRK -ILVDIMRANTTGDTNIRAGVP-GWPVADKTGTASYGTRNDIGVIWPPNRAPIVLSVLTDR -ATKDAGIDNKLLAQATAVAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=UPI0005DDFCEC ---DLADRFAELERRYDARLGGYVPATGTTAAI-EYRADERFAFCSTFKAPLVAAVLHQNP ---LTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H5MF16_9ACTN --dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGSNHDVGLAWPPGRSPIVMAVLTTK -REPDAAADNPLVAKTAALLAK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9143 TaxID=2184574 RepID=A0A3N8AAE2_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAELCAAMLQSGDKGAGNLLMGVLGGP -QTVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDTVQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAAREDVVASAARIATSAf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas chelatiphaga TaxID=517011 RepID=A0A0R0DGS9_9GAMM ----TAADFAALEKASGGRLGVTLLDTRTGKRT-GHRQDERFPMCSTIKWMIAAAALHRAE -GQPGFLDERLPMRSEDLIEHAPTTRRHVGKDLSVRDLCRTTMVTSDNPAANLLLRRLGGP -PALTAFMRSHDDAVTRSDRYEPELNRFIPGDPRDTTSPAASAASLQRFVLGDALQPASRQ -QLADWLIDNETGDATLRAGLGTRWRVGDKTGSNGKDTRNDIGVLWPLGGSAWVLTAYLQG -ASVDSGQRDAVLARVAAL----- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=UPI000CF3DFCA ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -DEKLDKNATAKVEKRNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNSMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000B8034CF --dELSRRLTDLEQQHSARLGVFAHNPATGRSV-LHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTAKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TTITRFCRSTGDRTTRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -QLTSWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGSNHDVGLAWPPGRSPIVMAVLTTK -REPDAAADNPLVAKTAALLAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. 24 TaxID=2545266 RepID=UPI00105B5F7E ----LSRRCQEWEHRHGGRVGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -RGEESLDRRLLVSREDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLIKSFGGP -GALTDFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA -QLAAWMIANKTGDRRLRAGFPDGWLVADKTGTSGLGYGNDIGVAWSRDRGAILVTVYCEM -PKAEAGARDRIIAEVAEMVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-475 TaxID=1463910 RepID=UPI00068AD3E1 ------PRLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS ---AGGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAANLLMRDIGGP -GALTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPRAIATDFRTLLLGTALPVRERR -LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRSAPLVLAVMTDR -PGRDAEPSDALIAEATRRTV--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax carolinensis TaxID=553814 RepID=A0A240UCM9_9BURK ---KWSDTLAGIERAAQGRLGVALLDTGSGLAL-GWRQDERFAMASTFKLLLAGWMLALVD -QVRERLDTRVHYAAADVVAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANVLLARHGGP -AGFTAFVQSLGDGITRLDRTEPTLNEAALGDPRDTTTPLAMLQTMQKLVLGDALTTLSRA -WLQRWLVETRTGDQRLRAGVP-GWTVGDKTGTADSGTANDVAVLWPPGGAPVLVTCYLTR -SAAKPAQRDAAIVQVARAVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007549A46 ---AAQSQLDALERASNSRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax sp. 6-D-6 TaxID=1177156 RepID=UPI00135B6571 ----LSRRCQEWEHRHGGRVGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -RGEESLDRRLLVSREDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLIKSFGGP -GALTDFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA -QLAAWMIANKTGDRRLRAGFPDGWLVADKTGTSGLGYGNDIGVAWSRDRGAILVTVYCEM -PKAEAGARDRIIAEVAEMVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=UPI0011A36B1F --------LVELERRYDARLGLFARNTATGRTL-AHRADERVAMCSTFKVYASAALLRAHG -LAGGYFERVLRYDAGQLVENSPVTETRVGVGMTIGELCAAALQHSDNTAANLLLRELGGP -RGITDFARAIGDPVTRLDRWEVELNSAIPGDERDTSTPRALADGLQELLLGDVLGAPERE -RLTGWMLGNTTGDTRIRAGVPREWRTADKTGGGSYGVANDIGVTWTGTGTPIVISLLTGR -PGEHDEADSALLADAARLIA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Stenotrophomonas sp. TaxID=165438 RepID=A0A1Y5Q422_9GAMM ---AAAANFAALEKHSGGRLGVCLWHPASGARF-GHRMEERFPMCSTFKFPLVAAVLHRAG -HGGLSLDQRVPVRQADILHHSPVSGRHVGKDMSVRDLCRATLTVSDNAAANLLLPLVGAP -AGLTAFLRGQGDAVTVAARREPELNSFAPGDPRDTTSPAAMAGNLQRFVLGDALGEIPRR -QLADWLIDNETGDERLRAGLPQGWRVGDKTGSGYDGISNDIAVLWPPAGTPWLLAAYLQG -ATQDASGRNGILRRAAELAAAH- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=V5RLB4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMTATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVACL---------------- ------------------------ ->[subseq from] TEM-169 beta-lactamase n=1 Tax=mixed culture bacterium PI_gF3SD01_11 TaxID=663181 RepID=C8C179_9BACT -------------------------------------------MMSTFKVLLCGAVLSRVD -PGQEQLGRRIHYSHNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-5 n=1 Tax=Enterobacter cloacae complex sp. TaxID=2027919 RepID=A0A2S0RJ30_9ENTR ------AKMKELETAFGGRIGVYLLNTGNGKEF-SYRQDERFPLCSSFKVFLAASVLKRIQ -SKSISLDDSVEYVGRVMEKHSPVSEKYREKGASVQTLAMAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDKRDTSTPKAVAMSLKNIAFGSILNAKNKA -LLQDWLKGNTTGNARVRAAVPDKWVVGDKTGTCGYGTANDVAILWPDNNSPAVIAVYTTR -PNQNDKHDETVIKNAAKIAID-- ->[subseq from] class A beta-lactamase n=1 Tax=Mesorhizobium sp. lm94 TaxID=2678685 RepID=UPI0012EED906 --dRLAETIHRVEDRLDARTGVMVRDTGSDWTW-AYRAEERFLMNSTVKPVICGAVLAEVD -GGALTLDEVLPIRDENLLSYAPVTETRVGESMSIGDLCLATLDMSDNTAANLLMDRLGGP -QEVTAFLRDIGDPVTRLDRREPELNTFAPGDPRDTTTPAAMLDTLQAMLLGDALTPASRA -QLAEWMSRGGVTGALLRAEAPADWEIADKSGGGDQ-TRNIVAMVTPRDHAPWLVAIYLSD -ADVDFVTRNAALQEIGAAVM--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodovibrio salinarum TaxID=1087 RepID=UPI0004B62451 ---KLADTVAQIEQSLDARVGVAVVDTGSGEAW-THRPDERFLMNSTAKVPICGAILAQAD -DGELALSETLPVHESDLLSYAPVTSEHVGDRMSLTQLCLAALDMSDNTASNLLLDRLGGP -EVVTELFRNADDPVSRLDRREPEMNSFAKGDPRDTTTPIAMAETMRALLLGDVLTPASRE -QLAEWMSHGAVTQELLRSHAPDGWVIADKSGSGSQ-TRNIIALISPPNAAPWIVTIFISD -AKADFATRNAALKEVSAAVM--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. RIT309 TaxID=1470590 RepID=UPI000450CD48 ----AAADFAALEKACSGRLGVTLLDSAGSRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDAALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWVLTAYLQA -GTISFEQRAAVLAQVGRIA---- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudolabrys sp. Root1462 TaxID=1736466 RepID=A0A0Q7TPM6_9RHIZ ------KRIADLETKLGGRLGVYVSD-ATGRVLiAHRDTERFPMCSTFKFLLGAAALKRAE -QGSITLDQVLPFGEADLLSYAPVTKANVGKGMSVHDLCAAAVTLSDNTAANLVMRAIGGP -AAVTAFARSIGDHDTQLDRFEPELNSAIPGDPRDTTTPRAIAEDLRRILAGNALAPTSVQ -MLEGWMTDSKTGLKRLRAGLPHDWSTADKTGSGANATANVVALVRPKSRPTLFVATYITG -ATLDGDALDAGHADVGRIISD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007527F02 ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia spinosispora TaxID=103441 RepID=UPI0003F97BD6 ----MAGRFQDLERRHGARLGVYGQNTRTGETV-AYRGGERFALCSVLKGLLAAHVLRDHD -RAGEFLARVIPYTRAELTAASPVTENFVGAGMAVRDLCAAAIIYSDNAACNLLLRETGGP -PALTTFMRSIGDEHTRLDRIEPDMSSSIPGDLRDTTTPEAIGRSYQRLVLGDALDPGDRD -LLTMWLKTTATSGKRFRAGLPTDWVIGDKTGTGDYGTANDIGIVWTSKGTPLVLSVMTTH -DAKDTAIDENLIVEATRLL---- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. JCM 19052 TaxID=1460647 RepID=A0A061Q3B1_9VIBR ---KLNEDLSAIEDHITGRIGVSVWDTQTDEKW-DYRGDERFPMMSTFKTLACATMLKDMD -SEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -HGVTRFLRSIGDKATRLDRFEPRLNEAKPSDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Nocardia ninae NBRC 108245 TaxID=1210091 RepID=A0A511ME19_9NOCA ------PRFVELEQQFGARLGIYALSTGTNRTL-THRADERFAFCSTFKALAAAAVLHHNP ---LTHLDKPVTVTKADIRSISPVTEKRVDTAMTIGELCDAAVRFSDGTAGNLLLDDIGGP -AGLTGYLRGLGDPVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQQLILGSALPEDKRA -ILTDWLVRNMTGAKRIAAAAPAGWTIADKTGTGDYGRANDIAIVWPTSHPPLVLAIMSDR -TGYDAEPSSELIAEAARHIF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 16K404 TaxID=2530385 RepID=A0A4R4UNB5_9PSEU ---------AELERRYDARLGLFARNVATGRTV-AHRADERVALCSTFKVYASAALLRAHG -LAGGYFDRVIRYDAGQLVENSPITETRVHTGMTVGELCAAAVQHSDNTAANLMLRELGGP -QAITEFARTIGDPMTRLDRWETELNTAIPGDERDTSTPRALGDGLQRLLLGDALGPAERD -RLTGWMLGSATGAARIRAGVPSSWRTADKTGGGSYGVANDIAVTWTDTATPIVISLLTGR -PREHDTANNALLADAARVVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A527TNI5_9RHIZ ----AEARLADLERKHRGRVCVSILDLASGTRI-GHRTSERILMCSTFKAMAAAFVLARVD -KGKEKLGRRIKFTKKELVEGSPATEMHVGGPMTVAELCDAAVTRSDNTAGNLLLTSFGGP -AGLTAFFRSLGDDISRLDRIETELNYDGPDDVRDTTTADAMLENLRKLLFTDILSGPSRS -QFAAWLINNKTGDTRLRAGLPKNWLVGDKTGTNGYGNANDIAVIWPSDRGPIIVTAYCEM -PSIAADERNAIIAEIGQFAA--- ->[subseq from] Beta-lactamase n=5 Tax=Streptomyces TaxID=1883 RepID=A0A380MQH4_STRGR ----AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDRR -LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ -PEEDAVRDDGLVADAARVLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000755CE4D ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLTMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGIKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. KK1-11 TaxID=2053005 RepID=A0A544ZFL1_9ACTN ---DVAAALRALETSFKGRIGAYAIDTATGKTI-GYRAGERFPLLSTFKAVAAAAVLARTT --DRELTRKVVHWTADEVKDYSPETSKHVEDGMTLAELARAAITYSDNTAGNMLLKRIGGP -EGLTRYFRTLKDPISRLDRWETELNDWSPKDRRDTTTPASAARDLRTLTTGDVLGAKDRS -RLIGWLRGNTTGDARIRDGLPKTWIVGDKTGTGSYGPANDIAVVWPRKGAPIIMAIYTNR -LAADGAADNKVIARTATVLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Salipaludibacillus neizhouensis TaxID=885475 RepID=A0A3A9KJ30_9BACI ----TNYSFEELEKEYDAKLGVYALNTGSNQSV-SYREDERFGYASAHKALAVGVLLKNKS ---IEELDEKINFTEEDLVNYNPVTEEFVDEGMTLKELSDASMRYSDNTAANLILEAIGGP -EGFKEVLREIGDDVTEPERIEPDLNDVSPGETNDTSTPKALAESLQSFTLGDVLSEEKQE -MLNDWLIRNTTGDNLIRAGVPEDWVVGDRTGSGSYGTRNNIAVIWPPNDDPIILSILSSR -EEPDADYDDELIAKAAEIAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=A0A561U6V6_9PSEU --------LVELERRYDARLGLFARNTATGRTL-AHRADERVAMCSTFKVYASAALLRAHG -LAGGYFERVLRYDAGQLVENSPVTETRVGVGMTIGELCAAALQHSDNTAANLLLRELGGP -RGITDFARAIGDPVTRLDRWEVELNSAIPGDERDTSTPRALADGLQELLLGDVLGAPERE -RLTGWMLGNTTGDTRIRAGVPREWRTADKTGGGSYGVANDIGVTWTGTGTPIVISLLTGR -PGEHDEADSALLADAARLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium sp. M2KJ-4 TaxID=2292704 RepID=A0A371P2N1_9ACTN ----ADAELAALEASSNARVGVYVRDTVTGRTV-AWRSGERFPFASTIKAPLAGAVLERVS ---HADLSRVVRFDRADLVPHSPVTEQHVDDGMPLRDVLDAALRFSDNTAANLLFDEIGGP -AGLDRALERLGDRLTDPRRIEPDLNTAVPGEVRDTTTPRALATTVGAYLLGDALPKDDRE -LLRTLMVTSTTGDGLIRAGVPDGWVVADKSGGAAYGVRNDVAIAYPPGRGPVLIAVMTRR -GQADDAYDDAAVAGATRIAVA-- ->[subseq from] Beta-lactamase n=2 Tax=Curtobacterium oceanosedimentum TaxID=465820 RepID=A0A147DR87_9MICO ---ATSRAFAALEEQYGARVGVVAIDTADGGSL-GYRADERFAFASTNKAFIAAAVLARSN ---TDDLDDVVRYDRSDLLSHAPVTSQHVDEGMTVRALVDAALRESDNTAANLLVERLGGV -GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSASDLRAVLLGDALDPDDRA -LLRSATAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDIAVVQPPGRDPIVLVVFTTR -DGADAEPSDALVAAATRVAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI0004B80A33 -----DREFRRLEKRFDARLGIYAIDTGTGRTV-RYQADERFAYGSTFKALAAAEVLDETT ---DAELEQVVRYSADDLVDYSPITEQHVAEGMTLRAIADAAVRYSDNTAGNLLLEHLGGP -ERFEKELKGIGDKVTDAARYETALNKATPGDRRDTSTARALTEDLREYAVDDALEPADRD -ILNAWLRGNTTGGELIRAGVPDGWVVGDKTGSAGYGTRNDIAVIWPPDRAPIVLAVLSSR -DEQDASYDT-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5123 TaxID=1463856 RepID=UPI0004E159D0 -----DAVFRAIEDRYGARVGLFLLDTGTGRTV-TYRPDRRFAACSTVKVLAAAALLRQEE ----TDLDRTLTYTRADVLAHAPVTSRHVAAGMALRDVMDAALRYSDNTAENLLLRELGGP -AGLQRAVRGLGDATTRTDRTEPSLNEAAPGDIRDTSTARALAADLRVLLVGNALPADRRA -LLTDWMTRNTTGGPYIRAALPAGWTAADKTGSGGYGTRNDIAVLRPPAAAPLVIAVLTSR -DHADTSSADALIADTTRAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. SPM TaxID=2170735 RepID=A0A363RY79_9GAMM -----AADFAALEKASGGRLGVTVLDTGSGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVSGGP -PALTAFLRTQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLSEKARL -QLADWLIDNQTGDACLRAGVGKRWRVGDKTGSNGEDTRNDIAVLWARGGTPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075413E6 ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLIGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain MC40-6) TaxID=398577 RepID=UPI000776AD73 -hhHHHAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA -QLTEWMTGGARGATAIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075BD064 ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Frondihabitans sp. PAMC 28766 TaxID=1795630 RepID=A0A126Z4G5_9MICO ---RTAAAFRALESRYGADLGVHAVDTRTGRTV-DFDADRRFAFASTYKALAAGVLLRRDT ---GAQLSQTIHYTAADLVDYSPITEQHLSTGMSLGDIIAAALQYSDNTAANLMLEQLGGP -QGLQSALRGLGDTTTNVDRTEPDVNTATPGDPRDTTTAAAIGTDLRAFVLGAALTPARRE -RLAALMRGNTTGGPYIRAGVPADWTVGDKTGNGGWGTRNDVGVAWLPDGDTVVVSILSDR -HTSGASSDDALLADATKAVV--- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=Q8RNV0_CITKO ----------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASMQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. CY41 TaxID=2608686 RepID=UPI0013571B46 -----HDRLIELEGKFDARLGVYARATGTGATI-AHRADERFAFCSTFKGLAAAAVLQRNP ---LSHLDTVVTYTRDDLLKNASVTPRHLDTGMTIRQLCDAAIRYSDGTAGNLLLRDLGGP -AELTAYARSLGDTVTRMDRIEPAITEATPGDPRDTTSPRAFGELYHRIVVGDALPPDKRD -FLRDLMERNATGAQRIRAGTPQGWTVADKTGTGDYGTLNDIAIVWPLASPPLVVAVMSSK -AARDASYDQGLLAEAAAYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB136 TaxID=2485181 RepID=A0A4R1KJ44_9MICO ---SADASFRRLEQQHDARLGVVAVDTGSGHRV-EYRQGERFAFASTNKTFIAAAVLAGAS ---DTDLETVVHYDRSDLLDYAPITSRFVDTGMTVRELIDASLRFSDNTAANLLVERLGGP -DAVERYLRGIGDRVTNVDRVEPELNEATPGDARDTTTPAQFATDLRKVVLGTTLEPTDRT -FLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPSGRAPLVVVVMTSG -KQSDATADDALVAAATKAAVA-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas indicatrix TaxID=2045451 RepID=UPI0013D8E9E1 ----AAADFAALEKACSGRLGVTLLDSAGGRRL-GHRQEERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRTQDLLEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFAIDDPRDTTTPAAIASTLQRLVLGNALRPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWILTAYLQA -GAISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. ZW137 TaxID=2485104 RepID=A0A3N1J0J3_9MICO ---SADASFRRLEQQHDARLGVVAVDTGSGHRV-EYRQGERFAFASTNKTFIAAAVLAGAS ---DTDLETVVHYDRSDLLDYAPITSRFVDTGMTVRELIDASLRFSDNTAANLLVERLGGP -DAVERYLRGIGDRVTNVDRVEPELNEATPGDARDTTTPAQFATDLRKVVLGTTLEPTDRT -FLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPSGRAPLVVVVMTSG -KQSDATADDALVAAATKAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005DE1547 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGSAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=UPI000992E853 ------TELAALERDFGGRVGVYALDTGSGATL-SHRANERFLMCSTVKTFIVSAILHRRL -SEPGLLDKQIQYTQSDVLEWAPVTSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDSQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVCDKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Arsenophonus endosymbiont of Trialeurodes vaporariorum TaxID=235567 RepID=A0A3B0LZ15_9GAMM ---------SKKKKKLNSRIGVAVIDTANNVTV-SYRGNKRFPLNSTFKALLCGMLLNQVG -NGKIVLTESVQFEKGQLVAHSPVTEKFIAPLMNWQQLCAAAISYSDNTAANLIEKKVGKP -TSFTRFLRSIGDRVTRLDRFEPELNSAIPGDKRDTTTPVAISQTLQKLVLGDVLQPSSRQ -QLRQWMEDDKVANALLRSVLPAQWKIADKTGTGDYGSRSIISLVWPEKRQPLIVSVYITQ -TKATLAQSNEAIARIGKAIFS-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE7661 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGQTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007589D1E ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000753AC05 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTDWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain MC40-6) TaxID=398577 RepID=B1YX81_BURA4 ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA -QLTEWMTGGARGATAIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseofuscus TaxID=146922 RepID=UPI00055A3FC8 -------AFADLERRYGARLGVYARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMEKVIHYPPHDLLPNSPRTEENQATGMAMAEVCAAAIQYSDNAAGNLLLRQLAGP -AGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALARSIERLALGRALAAPDRE -RFVTWLKGNTTSGARFRAGLPGGWTIADKTGTGDYASANDIGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. TaxID=1785 RepID=A0A3S0TED9_9MYCO ---DLSGQFADIERRYGGRLGVYVPESGTTAAI-AYRADERFALCSTFKAPLVAAVLHQYP ---LAHLDSMVSFTKADINSISPVTEQHVDTGMTVGQLCDAAIRYSDGTAANLLLTQVGGP -AGFTDYLRSLGDDTSRLDQAEPELNRDPPNDARDTTTPHAIALVFQKLVLGDALPPDKRT -MLTDWMARNTTGGKRIRAAFAADWKVIDKTGSGDYGRANDVAVVWSPKGVAHVIAIYTDI -AGYDAQPNEAFVADAARVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000578884E ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSNGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPASTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=2 Tax=Frondihabitans sp. PhB188 TaxID=2485200 RepID=A0A3N1QCP5_9MICO -------PFRALESRYSARLGVYAVDTGTGRTV-EYRSGERFTFASTYKALAAGVLLKTQT ---DAELDAVVRYSASDLVDYSPVTEKHVASGMTVRAIIAAALQYSDNTAANLLLEQLGGP -ADLTSALRSLGDDVTNVDRTEPDVNTATPGDPRDTTTPAAIAGDLRGFVLGGTLSRTRAQ -ELRDLLLGNTTGAPWIRAGVPAGWRVADKTGNASYGTRNDIAVVYPSTGDPIVLALLSDR -GVEGAASDDDLLADATKAVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4MZQ1_9ACTN ---RATKELRALETSFKGRIGAYAIDTANGRTI-AYRSDERFPLLSTFKAMACAAVLHKAR -TQPGLMNKRVRWTARDLVDYSPVTEKHVKDGMTVAGLCHAAITMSDNTAGNLILKQIGGP -AGLTRYFRSLKDRVSRLDRWETELNDWTPKSRRDTTTPSSIARDLRAVTYGKALNAKDRA -RLNAWLIANKTGDARIRAGLPKTWLIGDKTGTNSFGGGNDIAVIWPKKAAPIIMAIYTNR -RP-GLAADDKTIAKTAEVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Leo170 TaxID=1571199 RepID=A0A4Q8QVZ7_9BRAD --------FEAYERETGGRIGVYAENVATGAKI-TWRSDERFVMCSTFKASLAACVLARID -RGEDGLENVVRYRAADLLHHAPAARQNLSSGMSVADMCKAVVELSDNTCANLLLARIGGP -PALTAFWHETGDTVSRLDHYELELNRSPPGDPHDTTTPAAMAGNLRHFVLGEALSPASRE -RLTDWMLNCKTGNNRLRGGLPKDWKVGDKTGNNGKDAAGDIAVVWPRGGGPVLISAYTQG -GSPTTAQLEAVFAKIGQMVGRQf ->[subseq from] class A beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0004C477F9 ---DVAAALRALEASFQGRIGAYAIDTATGKTI-GYRAGERFALLSTFKAVAAGAVLARTT --DRELTRKVVHWTAGEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -RGLTRYFRTLKDRVSRLDRWETELNEWSPKQKRDTTTPASVARDLRALTTGDALGAKDRS -RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVVWPAKGAPIIMAIYTNR -RAADGATADKVVAQTATVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=A0A1Q4YV90_9ACTN ---RTDRAFAALERKFDARLGVYALDTGNGLFV-THRPDERFAYASTCKALLAAAVLDRNS ---LKELGRRVRIGRDVPVGHSPVTERAVGSELTLRELCDAAVRYSDNGAANLLFRELGGP -RGLQSALVAIGDRVTRCDRYEVALSDAVPGDVRDTSTARALATDLRTYVLDDALPAGKRA -VLTDWLRRNTTGDTTIRAGAPAGWQVGDKTGSGGYGTRNDIAIVWPPDAAPIAIAVLSRR -DTRDAERDDALIAGAAEVALN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides abscessus subsp. abscessus TaxID=1185650 RepID=A0A1N1CVH9_9MYCO ------DELASLEKDFGGRIGVYALDTGSGGTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLITQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=2 Tax=Kitasatospora sp. OK780 TaxID=1882771 RepID=A0A2N0JIW3_9ACTN ----VTRALADLEHEHSARLGVFARNTVTGAQV-LHRAHELFPVCSVHKVMTAAAVLRDLD -RDGTFLARRLHYTDRDVADYAPITGEHLGAGMTIAELCAAALDHSDNAADNLLLRQLGGP -AAVTRFCRSLGDGVTRLDRWEPALNSAEPERVTDTTTPAAIARTLADLVLGTALAPPDRR -LLTAWLRANTTGAGRLRVGLPAPWTLADKTGTGAYGTTNDVGIAWTTDGTPLVLAVLSTK -PDANAAADEPLIARAAALLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24484 TaxID=1463833 RepID=UPI0004C0B348 ------RALAALEREHGARLGVFARNAVTGAQV-RYRAHELFPICSVHKIVTAAAVLRDLD -RDGEVLARRIRYTAQDVADYAPVTGEHLAAGMTVAELCAAALDHSDNAADNLLLRELGGP -SAITRFCRSVGDRVTRLDRWEPALNSAEPGRVTDTTSPAAIARTLTDLVLGTALAPRDRR -QLTTWMLGNTTGAARLRAGLPSDWALADKTGTGSYGTTNDVGIAWTADRTPVVLSVLSTG -PEPYATADEALIAGTAALLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9CD7FE ---DLAETIRSWETALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Vibrio TaxID=2614977 RepID=A0A2U2IT56_9VIBR --sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2T1I186_STEMA ------ADFAALEKASGGRLGVTVLNAGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFTDWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. HCCB10043 TaxID=1396518 RepID=V6U6S2_9ACTN ---------------------MYAIDTGTGREV-THNDRARFAFNSTFKALQAAVVLSTYS ---LDGMDKRVTYTREDLVAHSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -RGLDASLERLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAVIRAGVPENWVVGDKTGTGSYGARNDIAVVWPPDSAPIVIAILSHR -GTKDAEPEDRLIAEAASVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 3MP-10 TaxID=2586635 RepID=A0A5N6A678_9ACTN -----AEEFDALEGEFDALLGVYAVDTGTGREV-AHRADERFAYASTFKALLVGAVLDEHG ---ANGLDEVISYTADDLLDNSPVTENFVDAGMSLRELCAAALWYSDNAAANLLLDVVGGP -GALEAWLRQLGDDTTRMDRWEPDLSEGTPGDDRDTSTPRALAADLRALLLGDALGDAERA -LLRQWMETNTTGETLVRAGVPAEWTVADKSGTAGYGGRNNIAVLWPDDGEPIVLAVMSRR -DQQGAERDDALIARAATVAVE-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6A0BZ91_STRDI ----AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDRR -LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ -PEEDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora rosea TaxID=58117 RepID=A0A1N7BVU4_9ACTN ---DVAAALRALEASFQGRIGAYAIDTATGKTI-GYRAGERFALLSTFKAVAAGAVLARTT --DRELTRKVVHWTAGEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -RGLTRYFRTLKDPVSRLDRWETELNEWSPKQKRDTTTPASVARDLRALTTGDALGAKDRS -RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVVWPAKGAPIIMAIYTNR -RAADGATADKVVAQTATVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14D1_NAIMI4_6 TaxID=2072410 RepID=A0A3S7K6V5_9GAMM ------ADFAALEKVSGGRLGVTVLDTGSGRRIaGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -PALTAFLRAQGDAVTRNDRYEPEMNRFAKGDPRDTTSPAAMAASLARFAVGNGLSTASRL -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGEDTRNDIAVLWPRGGAPWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. YC504 TaxID=1775132 RepID=UPI0013EA6188 -------EFGALEREYDARLGVYALDTANGREV-AYRADERFAYCSTCKAFLAAAVLDKRG ---VDGIDGEVTVRASDVEGWSPVTGKHIGARMALRSLCDAAVRYSDNGAANVLFRELGGP -RGLQSALRAIGDDVTRCDRYEVELSQAVPGDERDTSTPRAMARSLREFALGDVLADDERA -LLTGWLVRNTTGAKLIRAGAPDGWRIGDKTGNGSYGTRNDIALAWPPSGKPVVLAVMSRR -NGADAPHDDALIARASTAVF--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=A0A4R8S9N9_9MYCO -------ELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIHYTQSDIMEWAPVASQHLAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEEQLN--VPDGDLDTSTPLQLVTNLRRLVLDEGLDSQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI000754C74F ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLALSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. TN58 TaxID=234612 RepID=A0A1L7GNH2_9ACTN -----VRRLRALEREYGARVGAYARDTGTGRTV-RYRADELFPMCSVFKAPAAAAVMRDLD -RDGGFLARRIRYTAQDVAGGGSVTGENIAQGLTVAELCSAAIAQSDNCAANLLLRELGGP -SAITRLCRSVGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIARTYGRLVLGDALVPRHRE -LLTRWLVSNTTSGDRFRAGLPRDWVIGDKTGAGSYGTNNNVGIAWPPGRPPVELAVLTTK -PEAAAPRENALVARAAEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007525300 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLIGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=A0A1H2GXA0_9ACTN ---AVAAALAALETDYAARLGVYAVDTGTGETV-EHRPDERFAFASTHKMLSAAAVLQATE ---PADLAEVIAFDAADVVGFSPVTEPAAGTGLTLQQIIEAAITVSDNTAANLLFEQVGGP -DGLEAVVRDFGDEATSFDRIEPDLSDWVPGETRDTTTPRAMAANVEGLLLGDLLAEEDRT -LLHDTMRANTTGDELIRAGVPDGWVVADKTGSASHGGRNDIAVLEPPGAAPIVLAVYSNR -LDPEAESDPALIAAAAAIVVDEf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI000CE4A5E8 ---KLNEDLTTIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD -NEKLDKNATAKVEERSMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGTGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075AA3A4 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075A989F ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009270113 ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EGPTSAKGKPTIAAAARIALRAf ->[subseq from] class A beta-lactamase n=1 Tax=Sporosarcina sp. D27 TaxID=1382305 RepID=UPI0004716AAF --eTTKEKFEELEKEYDARLGVYAIDTGTKEIV-EFREDERFAYTSTSKALAAGVLLKQNP ---ISELEEIRTFTSEDIVPYSPITEGFVNKGMTLGKIAEAAMQYSDNTAGNLLFKELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGDSRDTSTPKALATNLEVFGVSEYLSADKQE -IFTNWLKGSTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIAIVWPPNREPIMIAIMSSR -DEEDASFNDELIAKATEVIAKAf ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio antiquarius (strain Ex25) TaxID=150340 RepID=A0A657N643_VIBAE --sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGQGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. TaxID=376 RepID=A0A160UJJ3_BRASZ ---DAQPELETYERESGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARVD -RGEDELAAMIPYGNVDLLEYAPVARQNIAAGMSVTEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDATSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLRRLVTGEALSTTSRA -QLTEWLVGCKTGANRLRGGLPASWKIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GTPSAAQIEIAFARIGRMLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis synnemataformans TaxID=61305 RepID=UPI0003450832 -----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRSDERFAYCSTHKAFTAALVLQQNT ---PEEMEEAVTYDADDVFGHSPVTGQHVDTGLPLVEVADAAVRHSDNTAANLLFDELGGP -DGFEEAMEEMGDDVIEADRVEPGLSRWTPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGNGSYGTRNDIAVLWPPEGDPIVLAVMSSR -EAEDAEYDNALVAGAAEVVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Nocardiopsis sp. JB363 TaxID=1434837 RepID=A0A1R3UJ43_9ACTN ---DVSAEFEALEEEFDARLGVYAVDTGSGDVV-AFQEDERFAFASTFKALLAGVVLSENS ---LEEMERVVTFDEGVLVPHSPVVEENLDSGMSLLELCDATVRYSDNAAANILLDEIGGP -EGFTEAVGETGDEVTNLTRYEVELNEATPGEERDTSSARAMAESLEAFTLGDVLPEDRRE -VLVDLLVRNTTGDDLIRAGVPQGWVVGDKTGSGGYGTRNDIGVLWPEEGDPIVLAVLSSR -DAEDAESDDALIAEASEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=UPI00075574FD ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGIGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. SL1 TaxID=2137478 RepID=A0A327I7P7_9GAMM ---DLERQLGELERSVDDRVGVALLNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -ESRETLDRRIVIEEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPELNTDHAGDERDTTTPLAMMATLRTLLLGDALSPSSRH -QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGEGNANDIGIAWPGDRGAVIAVAYTFM -PDASGAERDETIAAVGRLAA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio hyugaensis TaxID=1534743 RepID=UPI0005EEFFF8 ---KLNEDLTAIEEHISGRIGVSVWDTQTEEHW-DYRGDERFPMMSTFKTLACATMLKDMD -NEKLDKNATAKVEERNMVVWSPVMDRMVGQSTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTMFLRNIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLQTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRAGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas sp. X-1 TaxID=2571115 RepID=UPI00110B7768 ------KDFAALEQVSGGRLGVTLLEVATGRRL-GRRQDERFPMCSTFKALLAAHVLSLAD -AGTLSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP -PALTTFLRRQGDAVTRSDRYEPEMNNFAPGDPRDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGAPWVLVALLQG -ARVDADQRDAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces viridochromogenes TaxID=1938 RepID=UPI00069DA4B6 -----AGQFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG ---TDGIDKVVKYSRDDLVENSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLHELGGP -DGLEKALEDLGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKRDERE -LLRQWMTTNMTGRTLITAGVPDGWEVADKSGTAGYGGRNNIAVLWPDDGNPVVMAVMSTR -GKQGAERDDALIAKAATVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridochromogenes TaxID=1938 RepID=A0A0J7YXC9_STRVR -----AGQFRALEREFDARLGVYALDTGTGRSV-GYRADDRFAYASTFKALAAGAVLRKFG ---TDGIDKVVKYSRDDLVENSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLHELGGP -DGLEKALEDLGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKRDERE -LLRQWMTTNMTGRTLITAGVPDGWEVADKSGTAGYGGRNNIAVLWPDDGNPVVMAVMSTR -GKQGAERDDALIAKAATVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. 160415 TaxID=2495887 RepID=UPI00110C42DD ---QVRKDLRKLEASFKGRIGAYALDTATGRTV-TYRAGERFPMLSTFKAPLCAAALHRAR -AEPGLMDKLVKWTAADLRPNSPVTEKHVKDGLTVAQLCEAAVTVSDNTAANMVLKRIGGP -AGLTKYFRSLKDPISRLDRYEPELNDWTPKEKRDTTTPAAIARDLRLLTTGNALQAKDRE -QFNAWLLASKTGDARIRAGLPKTWTIGDKTGTNSTGGGNDIAVIWPEKGAPIIMAIYTNR -SP-GLATDDKAIAKTATILA--- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=bacterium YEK0313 TaxID=1522316 RepID=A0A0A1PLU1_9BACT -----GDRLRALETRRGGRLGAAIIDTASGASA-GHRADERFAMCSTVKFLAAAHALARVE -RGEDRLDRRIVVRPGDVVSHSPIAARRLGGPMTLAELCEAAITVSDSTAGNLLVGAAGGP -AGLTGYCRALGDTVTRVDHLAPFAASG-PNDANDTTSPRAMAENVRRLLLGEALRPASRA -QLTAWLVANRTGDERIRAGLPHGWRVGDKTGSGRGGECNDIAIAWPPGRAPLILSFYYVK -AGASAAVRNAVIAEATRLVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii TaxID=680 RepID=A0A344KNG4_9VIBR ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -DEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPADKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVFISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5643 TaxID=2690307 RepID=UPI001368DEE6 -------RLTDLERAYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRT ---LNGLDRRVTYTEADLRSTAPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -PKLTAYLRSLGDEVSRMDHYEPELHDVPPGDPADTTTPQAIATDFRRLLLGTALPARERR -LLMDWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTEPLVLAVMTDR -PGRDAEPSDALIAEATRRT---- ->[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0321 TaxID=2483797 RepID=UPI000FDB9C8A ------------AAAAGVTLSVSVTDLADGTTV-QSGEDARLKAASIIKLALLATLMADVD -AGELSLDQVVTIPAGDIVGGSGTLRDRTFPLITVRELAELMVQVSDNTATNVLIDVAGGF -DAVNDHVRDLGLEDLHLGRKMI--HPASPPLGENYITAAETTELIALIWHGQILSPTSSE -YIVDLMRGQLV-DTKYGAVIP-RPHLANKTGELAD-VSHDAGIILLPGRE-IALTTTTSF -GSIPRAEADAFVQETAQVVYD-- ->[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0321 TaxID=2483797 RepID=UPI000FDB9C8A -----------AENGIRVAVGYSDLTAEDGRLL--LGSPEPYNPASVIKLSLLATVMRQAE -RGLLDLDAPITISPYMVVGGSGTLQNEEPFTTTVREVARRMVVVSDNTATNVLLYYT-GI -PTTQALLDDLGLEVMRFNRQMFP--GDLIDSPPNVIDAADTLTLLEEMYRGDLLTTASRD -QILTWMSQQEV-DTKFGAVLG-DKPIAHKTGETGN-VTHDTGYFLVPGHE-SAVVVLTEV -TDETQRIGNPVVQDIGLAIYDY- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3R4Y0_9PSEU ---AAEKALAALETEWKGRLGVYALDTATGAAI-GHRADERFLMCSTHKALVAAAILKLRT -DRPGLLDKVIRYDKSQLQKHAPTTSQHVAEGMTVSALCEAAVTVSDNTADNLLFAELGGP -QAATAFVRTLGDQVTRMDRIEPDLNVG--GDERDTSTPAQLAADLRALVLGDALDPAGRD -LLAGWLKANTTGGKQIRAGVPSGWVVGDKTGSGFEGEINDIAVVWPPGRAPLVITVFTAP -ADPKSTAGAETVAKAATIVAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix texasensis TaxID=103734 RepID=UPI000F4C965C -------HLIELERKFDARLGVYAVATGTGTTL-AYRADEPFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVTYTEDDLMASSAVTRRHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP -AALTAYARGLGDTVTRSDRFEPDLTTAVPGDPRDTTSPRAIGVDYQRIVLGDALGPDQRA -FLRDLLERNATGAHRVRAGVPRGWAVADKTGTGGYGTVNDIAVVWPPDAAPLVISIMSSK -ATADAARDQALLAEAAAYAV--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S164 TaxID=1394697 RepID=A0A0I9QPZ9_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSLGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID2563 TaxID=2690255 RepID=UPI0013714F41 ----TTARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVIRYTKADIVPDSPVTGTALASGLSVARLCDAAIGDSDNTAANLLLRELGGP -QAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTTPSALARDYARLVLGKVLEPRDRE -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] Beta-lactamase n=1 Tax=Acrocarpospora pleiomorpha TaxID=90975 RepID=A0A5M3XAZ6_9ACTN ---------------------MYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP ---LSHLNKRVTYTSAEVNSISPITEDHIATGMTIRQLCDAAVRYSDGTASNLLVRDIGGP -AQLTAYLRGLGDTVSRIDNYEPELNRNPPRNPRDTTTPRAIAADYHKLVLGDALTTGKRA -MLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPNTAPLVMAIMSDR -SGYSTPHKESLIAEAAARIV--- ->[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI0014399DE1 ----LTGKLRDLERQHNARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRRDH --DGSLLGKVIRYTQEDVTKYGPITGKNLANGMTVSALCEATITYSDNCAANLLLRELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRTTDTTSPRAIGQSYARLTLGHALNRTDAD -QLTKWLLANTTGDNRIRAGLPAAWRWGDKTGTGKYSTTNDVGIAFPPGRAPIMIAVLSTK -KDPNGAADEPLVAKTAELVAGI- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00044F3EC7 -------ELVSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000258660A -------ELVSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075970DB ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075911D4 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces palmae TaxID=1701085 RepID=A0A4Z0HG85_9ACTN ------ARFAALEREYGARLGVYALATGSGAAV-AYRADERFAFCSTFKALAAAAVLDRNP ---LSHLDKRVTYSRADVDSISPVTEKHIATGMTIRQLCDAAVRFSDGTAGDLLMRDIGGP -ARLTAYLRGLGDTVSRMDDHEPELNRIPPHDPRDTTTPRAIAADYRELILGSALAPEKRA -LLKGWLQGNATGAKRVRAGLPRGWVAADKTGTGDYGRANDIAVVWPPHAAPLVLAVMSDR -RGYGASPKDALLADAARLVVS-- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H1Z4K9_9ACTN -------AVRELERAHDVTLGVSATNLATGARL-AHRSGDRFPILSVFKSIAAAAVLRDLD ---ESRLEHRVWYPPADIVLNSAITAEHVDTGMTVAELCDAAIRFSDNAAGNLLLRELGGP -RGLTAFARSIGDDATRLDRWEIELNSAEPGDVRDTSTPAALARTLAGLLVGDLLRPRDRR -RLRDWMLANTTSGPRFRDALPDGWRLADKTGAGDYGTNNDAGVAWNPAGQPIVIVAMSRR -DERDAPRVDAALADVARLVVR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119UQU2_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELAPGSPITERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderiales bacterium PBB5 TaxID=2015567 RepID=A0A257JLU5_9BURK --rALQASLAAIERRSGGRLGVHILHTGSGRHW-GWRSDERFPMCSSFKLLLVAMALSAQA -QGQLGLDERLRYGAGELVANSPITEAHVAQGMTVAELCAATLATSDNTAANVLLARLGGP -AAFTQHLRGLGDEVTRLDRYEPQLNGPGTQPDWDTSSPAAMARSLHRLVLGDGLPAAQQQ -QLIGWLQASVTGGRRLQAGLPSGWRIAEKTGTSN-GSTNDMGVVWPASGAPLVVVGFIRN -SRAPFAVREACLADVGRLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albofaciens TaxID=66866 RepID=UPI001239445D ------RRLRALEREHQARVGVFALNLATGATL-LHRAHELFPICSVFKTLAAAAVLRDLD -HDGTQLSRVVHYTAADVTKHAPVTKDHIDTGMTIRALCDATIRYSDNCAGNLLLRELGGP -TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTAPYAIARTYQRLVLGNALDRPDRA -LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPVVLALFTHK -PTQPTASGDPLVVKAA------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B7269 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFSQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora sakaeratensis TaxID=564415 RepID=UPI0012FA0E65 ------ADLRALETSFKGRIGLYAIDTATGKTI-AYRSGERFPLASTFKAVLAAAVLDKKP ----DILGKRIPIRKKDLVDYSPEVEKHVGSRMTVAALARAAVTKSDNAAANLLLRQVGGP -KGLTRYFRSLDDHVSRLDRNEPGLNLWHPAELRDTTTPAAVARDLKDLTAGDALDAGDRR -TFTGWLVANETGDKRIRAGLPKSWRVGDKTGTGGYGTANDIAIIWPKGSKPIIMAIYTNR -TDRNAAADDSVVARTATIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix texasensis TaxID=103734 RepID=A0A3N1HJZ1_9PSEU -------HLIELERKFDARLGVYAVATGTGTTL-AYRADEPFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVTYTEDDLMASSAVTRRHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP -AALTAYARGLGDTVTRSDRFEPDLTTAVPGDPRDTTSPRAIGVDYQRIVLGDALGPDQRA -FLRDLLERNATGAHRVRAGVPRGWAVADKTGTGGYGTVNDIAVVWPPDAAPLVISIMSSK -ATADAARDQALLAEAAAYAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C41DE ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHDSGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAMLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A2J0V3F4_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLQSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAQGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. 17Sr1-43 TaxID=2202828 RepID=A0A2U8VMY6_9RHIZ -----AARLAALAARVGGRVGVALRDTAIGETLlSLRAEERFPLCSTFKVLAAAAILARVE -RGAERLERALPLGPEDLQSYAPVARAKVEAAMTVEEACAAALLWSDNTAANLLLAALGGP -GALTAFLREQGDATTRLDRTEPDLNTAIPGDPRDTTTPAAMAATLDRLLLGDGLAPASRA -RLEGWMVESRTGLKRLRAGLPAAWTVGDRTGTGENGTANTVALLRPLGRAPLIATVYITG -LDGPVEARDAPHAEIGRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=UPI00099264E0 ------TELASLEKDFGGRVGVYALDTGSGATL-SHRANERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQSDVLEWAPVTSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVIDEGLDSQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVGDKTGSGFKGETNDIAVIWPPGRAPIVVVVLTVP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007607D3B ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMKIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] BETA-LACTAMASE PSE-4 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0000113014 --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADKSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMEERNDAIVKIGHSIFDVy ->[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0423 TaxID=2483799 RepID=UPI000F08B4E5 ------------AATAGVTLSVSVTDLADGTTV-QSGEDARLKAASIIKLALLATLMADVD -AGELSLDQVVTIPAGDIVGGSGTLRDRTFPLITVRELAELMVQVSDNTATNVLIDVAGGF -DAVNDHVRDLGLEDLHLGRKMI--HPASPPLGENYITAAETTELIALIWHGQILSPTSSE -YIVDLMRGQLV-DTKYGAVIP-RPHLANKTGELAD-VSHDAGIILLPGRE-IALTTTTSF -GSIPRAEADAFVQETAQVVYD-- ->[subseq from] serine hydrolase n=1 Tax=Georgenia sp. ZLJ0423 TaxID=2483799 RepID=UPI000F08B4E5 -----------AENGIRVAVGYSDLTAEDGRLL--LGSPEPYNPASVIKLSLLATVMRQAE -RGLLDLDAPITISPYMVVGGSGTLQNEEPFTTTVREVARRMVVVSDNTATNVLLYYT-GI -PTTQALLDDLGLEVMRFNRQMFP--GDLIDSPPNVIDAADTLTLLEEMYRGDLLTTASRD -QILTWMSQQEV-DTKFGAVLG-DKPIAHKTGETGN-VTHDTGYFLVPGHE-SAVVVLTEV -TDETQRIGNPVVQDIGLAIYDY- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4XJE1_9ACTN ---QAKKELRDLERSLGVRIGAYAIDTATGRTI-GYRSGERFALASTFKAMAAAAVLHKAR -TEPGLMDKVVKWTAAELKPNSPITEKHVKDGLTVAQLCHAAITRSDNTAANMLLKQLGGP -AGLTRYFRTLKDPISRLDRWETELNDWSPKEKRDTTTPAAIARDLRLVTAGDALPAKDRE -RLNGWLVANTTGDARIRAGLPASWIVGDKTGTGGYGTANDIAVAWPKKGAPVIMAVYTNG -RTAGAAAQDKALADTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI000E16B556 ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] Beta-lactamase n=1 Tax=Paraglaciecola arctica BSs20135 TaxID=493475 RepID=K6Z612_9ALTE ---EFTSKISALENNSGGRLGVSVISANGSALY-TYRENERFAMCSTFKALLGAAILSKVD -SNLESLDRAIPYTTKDILDYAPITKRNLSVGMTVSELSAASIQYSDNTAANLLLDAIGGP -QALTSYLRSIGDNQTRLDRNEPSLNTNITGDLRDTSTPNAMAETLHKVMFGDDLSPASKE -QLKAWMFGNTTGANKLKAGFNKFWIVGDKTGSCGNGASNDVAIVYPRGTEAFIISVFYTG -SSASNDIKNAVIADVAQIT---- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0007A04AEE ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLSEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia sp. LLH-Slr-13 TaxID=1564788 RepID=A0A097SRS0_9BURK ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLXRID -AGQEQLGRRLHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTSELLTLASRQ -QLIDWIEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRI------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces pristinaespiralis (strain ATCC 25486 / DSM 40338 / CBS 914.69 / JCM 4507 / NBRC 13074 / NRRL 2958 / 5647) TaxID=457429 RepID=D6X962_STRE2 ------RAFARLQREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEHNS ---LAGLDKVVRYTRDDLVAHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP -KAFQAVLAALGDTTTHADRLETALNAATPGDIRDTSTPRALAHDLRAYALGDVLDAEKKA -LLTHWLKGNTTGDALIRAGVPDTWQVGDRTGAGAYGTRNAIAVAWPPGAAPVVIAVLSSR -AENS-PIAKAAF----------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Go-475 TaxID=2072505 RepID=A0A2Z5K4V4_9ACTN --------LADLERAYGARIGVHALATGTGATV-VHRADERFAFCSTFKALAAAAVLHHRS ---PHDLDRRVTYTRADLRSTTPITGRHLATGMTLRQLCDAAVRFSDGAAGNLLMREIGGP -AQLTAYLRGLGDKVSRMDHYEPELHDVPPDDPSDTTTPRAIATDFHRLLLGTALPARDRA -LLMDWLSRNATGARRIRAGLPRGWKVADKTGTGDYGRANDIAVVHPPRAEPLVLAVMTDR -PGRDAEPSDALIAETTRRTV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008FE4B2F ----AQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERV -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Desulfoluna spongiiphila TaxID=419481 RepID=UPI00125EF241 ----LENRIKEIEHALGARVGVSLYEVETSESW-SYKGDIRFPLMSTFKTLACAKTLLDVE -QKKVSFDDSVVIEKTSLITWSPVTKHHAGQAFSLKQACAAMMIMSDNTAANIVLDKTGGP -TALTAFMRSIGDAVTRLDRMEPELGEALEGDVRDTTTPNAMADSLHVLLFGDVLSKASKT -QLTQWMRSNKISGSLLRSVLPDGWTIADRSGAGGHGSRGITAVVWPETQPPFIVCMYLTQ -TKASFDERNKAIAEIGRELFKLy ->[subseq from] class A beta-lactamase n=1 Tax=Kineosporiaceae bacterium B12 TaxID=2609562 RepID=UPI0014300498 ---QLEAAFTGLEAEFGARVGVYAVDTGTGAVV-EHRADERFAHASTIKVAAVAAVLDAAT ---PADLDEAVPVPADGIVTHSPVTAAHAGGAVPLREVLAAALTVSDNTAGNLLLDRAGGP -AGLQAFLRTAGDDVTRVDRREPDLNTAVPGDPRDTTTPRALAADLRAFAVDDALGADDRA -VLTDLLRRSTTGAGLVRAGVPAGWGVEDKSGTGGYGTRNDAAVVRPPGRAPLVVVVMSSR -PGADAEPDDALLARATEVVV--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. Leaf70 TaxID=1736233 RepID=A0A0Q4QFW8_9GAMM -----AAGFAALEAESGGRLGVCLWHPASGARF-GHRMDERFPMCSTFKFLLAAAVLHRAG -RGRLSLDQRVPVRKVDILGNSPVTARHAGKDLSVRDLCRATLTTSDNAAANLLLPLVDGP -AGLTAFLRAQDDAVTVAARYEPEANRFAPGDPRDTTSPAAMAGNLQRFVLGDVLDEASRR -QLADWLIDNETGAARLRAGLPGGWRVGDKTGGNGRDTTNDIALLWPEGGSPWVLAGYLQG -SALDDDGRNAILRRVGEVAGD-- ->[subseq from] Beta-lactamase n=1 Tax=Leifsonia sp. 98AMF TaxID=1798216 RepID=A0A1I4RGV7_9MICO ---AAARALAELESQYGATVGVYAVDTGTGRSV-GYRQDDRFAYASTSKVLLAGAVLARSS ---DEQLDAVVPYTSDDLVSYSPITETMAGAGMPLRDVIAAALQKSDNTAANLLFRQLGGP -AELEKSLRALGDETTEVERTEPDLNEAAPGDPRDTSTPRALAADLRAYALGEELPANRRK -LLVDDMTGNATGDPLIRAGAPTGWTVSDKSGAASYGTRNDIAVLTAPGHAPVVMVVLSRK -ADKDAAYDNALVADTAKVL---- ->[subseq from] Beta-lactamase (Fragment) n=5 Tax=Rahnella TaxID=34037 RepID=D7PIH9_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura macra TaxID=46164 RepID=UPI00082F657A -------RLSELERSYKGRIGAFALDTGNGRVV-SYRAHERFPFASTFKAMTGAAILHKAR -RDPGLLDRRLHWTKKDLLPNSPITEQHVEDGLTVAELCHAAITRSDNTAANVLLGQLDGP -AGLTRFLRSIKDPVSRLDRYETDLNIWKPGQKRDTTTPAAVGRDLAGLAVGRTLAPPDRA -RLNGWLRANLTGDARIRAGVPKGWIVGDKTGTGSYGTANDIAVVTPPHHAPLIIAVYTNR -KDPKGQADESVIARTTSILVD-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=A0A078LI87_CITKO ----------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=UPI0011A7F404 ---DLGQVLADLEKQSQGRLGVALTDTATGQVA-SHRGDERFMMLSSFKTLSAAYILARAD -RGEEQLARRIPIAQSDLLDHAPVTKQHVGARMTLAELCHATITTSDNTAANLMHRSYGGP -QALTRFVRSLGDPITRHDRYEPELNVPHVSEPLDTTSPHAMNRTLGALLFGQALKPESRR -MLQSWLVANQTGGTRLRAGLPSDWTVGEKTGTYSKVGANDAGFARAPGGAPIVVSVYLET -TAIDMPERDRIIAEVGRLVA--- ->[subseq from] L2 family class A beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8J7H5_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLQSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAQGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI000B598546 ---KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSEMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGIMAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Bacillus manliponensis TaxID=574376 RepID=A0A073JSD7_9BACI ---TVIEKFEQLEKEYDARLGVYAIDTGTKETI-EFRENERFAYTSTFKALAGAVLLKQNP ---ISALEEIRTFTDEDIVTYSPITEDFVNKGMSLGEIAKAAIQYSDNTAGNLLFEELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGDSRDTSTPKALATTLEVFGISEYLPADKQE -IFTNWLKGNTTGDSLIQAGVPEGWEVGDKSGAGSYGTRNDIAIVWPPNREPIVIAVMSSR -KEENASFNDELIAKATKVITQAf ->[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI0009BAE122 ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. OK270 TaxID=1882814 RepID=A0A285DYY1_9NOCA ---SLDTKLDALEARYSTRIGVTAIDPATGQIY-QHRGDERFALCSTFKTYAAAEVLRRTR -AGTSSLDKPVLVEPGDLVENSPVTAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP -PAITSLAREIGDESTRLDRWETELNSALRGDPRDTSTPKELADGYQALLLGDALRSPERA -QLVDWMRASKTSDKRIRAGLPDGWTAAAKSGAGRFGTVNDAGVAWDRDGNPLVLAILTDS -LTEDAQGNNQVVADTTAAVVE-- ->[subseq from] Beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=Q708V4_CITKO ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758E346 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8MX89_9ACTN ---RATKELRALETSFKGRIGAYAIDTANGRTI-AYRSDERFPLLSTFKAMACAAVLHKAR -TQPGLMNKRVRWTARDLVDYSPVTEKHVKDGMTVAGLCHAAITMSDNTAGNLILKQIGGP -AGLTRYFRSLKDRVSRLDRWETELNDWTPKSRRDTTTPSSIARDLRAVTYGKALNAKDRA -RLNAWLIANKTGDARIRAGLPKTWLIGDKTGTNSFGGGNDIAVIWPKRAAPIIMAIYTNR -RP-GLAADDKTIAKTAEVLA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0006A7068E ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNQIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI00062BF411 --sQLNEDISLIEQQTSSRIGVSVWDTQTDDRW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia ninae TaxID=356145 RepID=UPI0011BE9039 ------PRFVELEQQFGARLGIYALSTGTNRTL-THRADERFAFCSTFKALAAAAVLHHNP ---LTHLDKPVTVTKADIRSISPVTEKRVDTAMTIGELCDAAVRFSDGTAGNLLLDDIGGP -AGLTGYLRGLGDPVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQQLILGSALPEDKRA -ILTDWLVRNMTGAKRIAAAAPAGWTIADKTGTGDYGRANDIAIVWPTSHPPLVLAIMSDR -TGYDAEPSSELIAEAARHIF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SLBN-192 TaxID=1119093 RepID=A0A542TVH3_9ACTN ------PRLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKAPAAAAVLHHRS ---ASGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -AALTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRTLLLGTALPLRERR -LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRSSPLVLAVMTDR -PGRDAEPSDALIAEATRRTV--- ->[subseq from] Carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A660AGX4_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLASATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ok210 TaxID=1761905 RepID=UPI000B876E44 ---RTARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTIGAAAVLRDLD -RRGEFLARRIRYTAQYVEANSPITGRNLSGGMTVAELCAYSITHSDNTAANLLLRELGGP -GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRGTDTTTPRAVGRTYARLVLGDALVPCDRR -LLTGWLLANTTSGERFRAGLPADWTVADKTAGGSYGGNNNAGIAWPPGRPPVVLAVMTTK -PDRDAPADNPLVARTAGVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075CF16A ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTVGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax xenomutans TaxID=1094342 RepID=UPI0009B6DC0B ---ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -QGQESLDRRLLVSRKDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP -GALTEFLRENGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA -QLAAWMIANKTGDRRLRAGFPANWLVADKTGTSGLGYSNDIGVAWSPARGAVLVTVYCEM -PKAEAEARDRIIAEVAEI----- ->[subseq from] class A beta-lactamase n=1 Tax=Erwinia oleae TaxID=796334 RepID=UPI00068A72C9 -------KAQAIEKRLNARVGMAVIDTGSDRRW-LYNAEARFPLNSTFKAFACGALLYQAD -AGKNDLNKATRVTREEMIPYAPVAEKLIGQSVSLDRLCAATMRTSDNVAANKILASIGGP -EGMTHFMREIGDSVTRLDRREPDLNEAMPGDLRDTTTPAAAVASLRKLVLGNVLSVASRE -KLTRWMIEDAVGGPLLRAGIPSAWRIGDRTGAGGHGSRSVIAVMWPPSHAPVVVAVFITE -TTATMEVRNAAIAELGAALAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. D16R12 TaxID=1855662 RepID=UPI000993911C ------TELASLEKEFGGRVGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAVLHRRL -SEPGLLDKQIHYAQSDIMEWAPVASQHLAEGMTVSELCDATIRYSDNTGANLLISLLGGP -KQTEKFVRSLGDNVSRMDRTEEQLN--VPDGDLDTSTPLQLVTNLRRLVLDQGLDPQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=A0A1B4C018_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPERA -QLTEWMTGGARSATGIAAGVPPGWRIADKIGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATSAf ->[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 16K309 TaxID=2530384 RepID=A0A4R4VY68_9PSEU ---------AELERRYDARLGLFARNVATGRTI-AHRADERVALCSTFKVYASAALLRAHG -LASGYFDRVIRYDAGQLVKNSPITETRVDTGMTVGELCAAAVQHSDNTAANLMLRELGGP -QAITEFARGIGDPMTRLDRWEVELNTAIPGDERDTSTPRALGEGLQHLLLGDALGPAERD -RLTGWMLGSATGAARIRAGVPSSWRTADKTGGGAYGVANDIAVTWTDTGTPIVISLLTGR -PREHDTANNALLADAARLVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MMLR14_010 TaxID=1898743 RepID=UPI0009F4ADFA ---ATARAFRTLERDHGARLGVTAIDTGSGQRV-TYRSGERFPFASTNKVFVAAVVLAQSS ---GADLDTVVHYDRSDLLAHAPVTTRSVDTGMTVRALLDAMLRYSDNTAANLLVERVGGP -AVVEQALRDLGDRTTNVDRVEPDLNEAVPGDARDTTTPAQFAADLRQVLLRSALDPSDRR -MLRESMLGNTTGDATIRAGVDPAWAVADKTGTGSYGVRNDIGIVFPTGRAPIVVVVMTSK -DTADAEPDDALVAAATRTAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Belnapia moabensis TaxID=365533 RepID=UPI0005B9AAA1 ----AAEGLAALEARQGGRLGVAILDSGSGRVL-AHRGEERFALCSTFKHLAAARVLARVD -AGEEWLDRHVAYGREALVPYSPVTGPGAEAGLAMGAICEAAVALSDNTAGNLMLDSFGGP -AGLTSWLRGLGDGATRLDRRETELNVVPPGDERDTTTPLAMVGTMRRLLLGEALSAGSRE -RLVGWLVGSKTGDARLRAGMPAGWRVGDKTGTGPAPPTNDVAIAWPPGQAPVIVAAYLEG -ARGSDAERSAVLAEVGRVAA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. WZN-1 TaxID=2005046 RepID=A0A1Z2LMX5_9GAMM ------ADFAALEKASGGRLGVTVLNTGDGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVDKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. YR399 TaxID=1884371 RepID=A0A2M8VUM4_9GAMM -----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRATDILEHAPVTRRHVGKDLAVRDLCRATLITSDNIAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGSPWIVTAYLQA -GAISFEQRAAVLAQVGRIA---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter glycinis TaxID=582702 RepID=A0A1I3Z3F5_9GAMM ---AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD -RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKSVGGP -AAATRFVRSLDDDITRLDRHEPELN--VPDRNLDTTTPDAMLASLRKLLLGNVLSASSRA -QLIDWLRHNTTGETQLRAGMPASWQAGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG -PADQGDMRKAVLAHVGKLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudorhodobacter sp. MZDSW-24AT TaxID=2052957 RepID=A0A2M8MUY0_9RHOB --dRLAATIERIERDLDARVGVVIRDSGSAWSL-GHRADERFLMNSTFKTMLCGAVLRRVD -DGVLSLDEDIAIRDSDLLDYAPVTETMVGKSMSIGELCFAALDMSDNTATNLLIDRIGGP -QSVTAFLRDIGDPVSRLDRREPDVNNFAPGDPRDTTTPDAMALTMDALLNKDALTAESRA -RLVDWMSAGGVTGALIRASTPEGWQVADRSGSGDF-NRNIAAMVTPPGKAPYFISIFLSD -ADADFATRNAAVIALSEAVMQ-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI000996A535 ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQRTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. KhCrAH-43 TaxID=1305827 RepID=A0A327V7D7_9ACTN ----TTARLRELERAHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVVHYTEADCVSDSPVTDTHLESGLSVARLCDAAIGDSDNTAANLLLRELGGP -AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRE -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTPGGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia piptadeniae TaxID=1701573 RepID=A0A1N7RYR2_9BURK ----AHKRFEQLEARSGGRLGVAALNTADGAYV-GYRESERFPMCSTFKLLAVAAILKRSI -AERALLDTHIRYGETDLVANSPVTKRHVSEGMSMGDICAAALQYSDNTAANLLLTALGGP -EVLNEFARSIGDTWFNLVRREPELNDAVPGDMRDTTTPRAMMHDMQKILLNDVLEPPQRE -KLKTWLLGNTTGERRIRAAVRTGWPVADKTGSGDYGTANDVAVVYSPAAA-FVVAVYCTG -LTKETPPQDEVVDEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007596253 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMKIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. XY006 TaxID=2021410 RepID=A0A231P6Z6_9ACTN -------RFADLERAYGARVGVYALATGTGATV-VHRAGERFAFCSVFKALAAAAVLHHRS ---PHDLDRRVTYTRADLRSTTPVTGRHLATGMTLRELCDAAVRFSDGAAGNLLMREIGGP -GKLTAYLRALGDRTSRMDHYEPELHDVPPDDPRDTTTPEAIATDFRRLLLGTALPAGDRA -LLLDWLSRNATGARRIRAGLPRGWRVADKTGTGHYGRANDVAVVHPPRGEPLVLAVLTDR -PGRDAEPSDALIAEATERT---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium pseudokansasii TaxID=2341080 RepID=A0A498QTM3_9MYCO ---DLQSRFAELEHRYAARLGVYVPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQHP ---LSHLDKVVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT -SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTAHAIALDYQQVVLGEALPPDKRA -MLTDWMARNTTGANRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR -APYDAEWSEALIADAARCVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia vaccinii TaxID=1822 RepID=UPI0009FE47EA ----LSGRFGALERRFGARLGVFALDTGSGRTV-EYRADERFAFCSTFKALEAGAILATAG ---PAELERRISYTATDFTAYAPIARQHVADGMTVRELLDAAVRYSDNTAANLLFGLLDGP -PGLQRDLRNLGDQVTRSDRVEPALSQAVPGDPRDTSTPRAIAADLRAYVLGNTLPTDGRA -LLTTMLRTNTTGAGLIRAGVPADWVVGDKTGNGDYGTRNDIAVLWPPHRAPLVLAVMSTR -GGRDDSFDNALIAQSANVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BA2 TaxID=436595 RepID=UPI00132454A2 ---ELAKQLSGLEQEYSARLGVFARDTVTGRTV-TYRADEHFPMCSVFKTLAAAAVLRDLD -RNGTFLAQRIRYTSEDAMNYHPITGRNLADGMTVGELCAAAVSHSDNGAANLLLRELGGP -TAITRFCRSIGDKTTRLDRWEPALNSAEPWRKTDTTSPRAIGHTYARLILGNALAGEDRS -RLTGWLMSNTTNGERFRAGLPADWTLADKTGGGEYGVANDVGVVWPPGKSPLVLAVLSTK -HAPEGPTDNPLVAKTVTL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces cacaoi subsp. cacaoi TaxID=66857 RepID=A0A4Y3QVW9_STRCI ---AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS -AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLGGP -KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE -QLNDWMSGNATGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG -DTQDAEPHDELVAEAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F597FB8 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNQAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PEATAAARADVVASAARLAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011226CF7 ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTN -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111F2CEA ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGGERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI000CDE117E ---DLQNRFAELEHRYAARLGVYMPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQYP ---LSHLDEMVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT -SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQVVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR -ASYDAEWSEALVADAARCVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 9128 TaxID=1793722 RepID=A0A181ZF26_9MICO ---STDRAFAALEHQHDARLGVTAIDTASGHRV-SYRSDERFPFASTNKTFIVAAVLAHDS ---DADLDTIVHYDRSDLLEYAPITSRFVDTGMTVRELIDAAMRFSDNTAANLLVERVGGP -DAVERYLRGIGDRTTNVDRVEPDLNEATPGDDRDTTTPAQFASDLRQVLLGKTLDTTDRT -LLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPTGRAPIVVVVMTAT -DRSDAKADDPLVAAATKQAV--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC712 TaxID=1848329 RepID=A0A4V2YDT6_9ACTN ---RAAKELRALETSFKGRIGAYAIDTATGKAI-AYRSGERFPLLSTFKAMACAAVLHKAR -TRPGLMKKRVRWTARDLVDYSPVTEKHVKDGMTVAALCHAAITMSDNTAGNMVLKQIGGP -KGLTRYFRSLNDRVSRLDRWETELNDWTPKSRRDTTTPSAIARDLRAVTYGKALNAKDRA -QLNAWLIANTTGDARIRAGLPRTWTIGDKTGTNSFGGGNDIAAIWPDKGAPIIMAIYTNR -TP-GLAADDKTIAKTATILA--- ->[subseq from] Beta-lactamase n=2 Tax=Actinomadura meyerae TaxID=240840 RepID=A0A239J9W7_9ACTN ---DVTRQLTRLEKIRSTRIGAYAIDTGTGQVV-GHRADETFPFASTFKAMACGAVLRKAR -QAPGLLDKVIHYTEDDLQEFSPVTEKHVGTGMTVAELCHAAITRSDNTAGNLVLEQIGGP -AGLTAFFRSLGDTVSRSDRTEPGLNLWKPGEKRDTTAPRPWADDLRALTTGNALAPADRT -RLIDWLKATVTGDKRIRAGLPKSWTVGDKTGTGGYGSANDMAIAYPKGGAPLIMVVTTTR -KGEDAAADEKSIALTAGVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura amylolytica TaxID=1411117 RepID=UPI000E6C2975 ---EVRRRLRALEAEYGGRIGAYAIDTATGRTV-GYRAQETFPMLSTFKAMACAAVLHKAR -ADPGLLERVIRYTADDLVDHSPETGKNLKAGMTVSALCEATITLSDNTAGNLVLRQIGGP -AGLTAYLRSLGDPRSRLDRWELELNDWRPGERRDTTTPALMAQNLRKVTTTDALAGPDRA -RLIAWLRANTTGDARIRAGLPGDWTVGDKTGTGGYATANDIAIVWPEGAAPLIMAVYTNR -GTPDATADNTFVARTATILAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium setense TaxID=431269 RepID=A0A0B2YQA1_9MYCO ----IDDQIAELERRDNALIGLYATNLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG -RKQISLDNRVFVDPDAIVEYSPVTEPRAGGEMTLGELCRAALQQSDNTAGNLLLKTIDGP -PGITAFARSIGDQRTRLDRWETELNSAIPGDPRDTSTPAALAGGYREILAGDALSPPQRR -QLQDWMRANET--SSVRAGLPEGWTTADKTGSGDFGSTNDVGIAYGPDGQQLLLAVMTRS -QADDADNLRPLIGELAAL----- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU16741 TaxID=2015347 RepID=A0A228HJ42_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTVAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARGAAGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Ideonella sakaiensis (strain NBRC 110686 / TISTR 2288 / 201-F6) TaxID=1547922 RepID=A0A0K8P1S2_IDESA ---------AGLEAAAGGRLGVAVAG-PSGPLD-GHRLDERFPMCSTFKWLVAARVLQRVD -AGEERLARRLPVTARDLVAHSPVCERHVGATLSLAELCHATITTSDNAAANLLLPALGGP -EGLTRWLRTLGDLVTRLDRWEPHLNEAAPDDPRDTTTPRAMLGLLRTLLLGDVLAPGSRA -TLAGWLEATETNTTRLRAAVPPGWRMGSKTGAGANGATNDVGLYWPPGRPTILVAAFLVG -TSAPTARRHAAIAEVGRRAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0006AC664B ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGTRATTGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAVRADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. HF10 TaxID=2692233 RepID=UPI001316A8F5 ------GELADLERRYGARLGVYARNVRTGRVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQATGMAMADVCAAAIQYSDNAAGNLLLRRLDGP -GGLTRFFRSLGDEVSRLDRWEPELNTAIPGDPRDTTSPEALATSIERLALGRALAAPDRE -RFVGWLKGNTTSGARFRAGLPAGWTIADKTGTGDYASANDLGVAWTTRRTPVVLAVLSTK -EGKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia vulneris TaxID=1141657 RepID=A0A0C1D8U6_9NOCA -----HDRLFELERKFDARLGVYALDTASGATV-THRADERFAFCSTFKGLAAAAMLQRNP ---LSHLDTVVRYTDEDLTKNAAITPQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDIGGP -AELTAYLRGLGDPITRMDRIEPAITEATPGDPRDTSSPRALGTDYQRIVLGDALPEDKLA -FLRDLLERNATGAGRVRAGVPQGWKVADKTGTGDYGTLNDIAIVWPPDRAPLVLSLMSSK -ATADAEYDQALLAEAAAYVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0002316F31 ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=UPI000B7D7A32 ---TVTGKLRELEKQHNARLGVFAADTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRKDR --DGTLLGKVITYTQSDVDKHGPITGRNLANGMTISALCEATITYSDNCAANLLLRELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD -QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR -KDPTGAADEPLLAKTAELVAATf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 344-Salad TaxID=678973 RepID=D7PIJ5_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLTRSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAK----------------- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=A0A4V3I0G8_9MYCO ------TELDALERDFGGRVGVYALDTGSGATL-SHRANERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQSDVLEWAPVTSQHVAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDSQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVGDKTGSGFKGETNDIAVIWPPGRAPIVVVVLTVP -DDPKSTKGKPTITAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=UPI0009969D0B ------RAFARLQREFDARLGVYAVDTGSGRTV-THRPDERFAYCSTHKALTAAAVLEHNS ---LAGLDKVVRYTRDDLVAHSPVTEKHVDSGMTLRAVCDAAVRYSDNTAANLLFDELGGP -KAFQAVLAALGDTTTHADRLETALNAATPGDIRDTSTPRALAHDLRAYALGDVLDAEKKA -LLTHWLKGNTTGDALIRAGVPDTWQVGDRTGAGAYGTRNAIAVAWPPGAAPVVIAVLSSR -AENS-PIAKAAF----------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759A2A5 ---AAQSQLDALERASNGRLGIAALDTVTGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. EC-SD404 TaxID=2038389 RepID=A0A5E7XXE6_9RHIZ ---RLQEVVSTIEEDLGARVGIVVRDTGSDWQW-AHREDERFLMNSTFKSVLCGAVLQRAE -NGELALTDALEIEASDIQDYAPVAETRVGETMTVGELCLATLDMSDNTAANLLIDRLGGP -QEVTAFVRTLGDGVTRLDRWEPEMNTFAEGDPRDTTTPSAMAASWEAMLLGDGLSAAAQD -QLVDWMSIGGVTGALLRASTPDDWLVADKSGSGNR-TRNLVAMVTPPDEAPYLVSIYLSD -TSADFETRNAAVTEVGAAIVD-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111E6003 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIVQISQLILEHy ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI00066A2D0B ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATTKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter pseudonitzschiae TaxID=1402135 RepID=A0A221K3Q0_9RHOB --eTLEQTVDQIETKLDGRIGISLIDTGSGFTW-SHRQDERFLMNSTVKVPLCGAVLARVD -AGTLSLSEQLPVVQADIQSYAPVTEQRVGQSMNIAELCMAAIDMSDNTAANLLIDHLGGP -QAITQFFRSTGDIESRLDRREPELNTFAPGDPRDTTTPVASTDTLYALLLGDVLSDRSRK -QLADWMSHGGVTGQLLRAKAPAEWQIYDKSGSGSH-NRNLVAMVTPESRAPWIVTIFLSD -MDEDFETRNAALQDISRAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=Q708V3_CITKO ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASAQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756EFE5 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRECFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces viridosporus (strain ATCC 14672 / DSM 40746 / JCM 4963 / KCTC 9882 / NRRL B-12104 / FH 1290) TaxID=566461 RepID=D5ZPK2_STRV1 -------SLADLERAYGARIGVYAVATDTGATV-VHRADERFAFCSTFKSLAAAAVLHRNP ---LSRLDERVTYGRADLAAHSPVTERHVATGMTVRQLCDAAVRYSDNTAANLLLRDLGGP -RGLTTYLRGLGDRVSGLDHYEPELNRNPPGDPRDTTTPRAIAVDHRALVLGDALPAARRA -LLKDWLVRNTTGDRRIRAGVPRGWTVGDKTGTADWGRAHDVAVLWPPRAAPLVLAVL--- ------------------------ ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI0011211AE2 ---KLNEDISLIEIQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Agreia sp. Leaf244 TaxID=1736305 RepID=A0A0S9DWG6_9MICO -------AFAQLEQEFDARLGVYALDPLSRAEV-AYRADERFAYASTFKALAAGILLKTVP ---DEQLDELVSYGADELLPNSPVTEANVDEGMTLRAVAEAAVRFSDNTAGNIVLERLGGP -EGFTQALRDLGDTTSSSDRIETDLNSAIPGDTRDTSTPRAFALDLATLLTTDALGAAQQS -QLIDWMTGNATGSELIAAGLDAGWSVADKSGAGAYGTRNDIALVWPPSGSPIVLVIMSNR -PTEDAEYDNALIARATEAAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Klenkia brasiliensis TaxID=333142 RepID=A0A1G7SFY2_9ACTN --------VDALEAAYAARVGVWALDTGTGQVL-EHRADERFAHASTLKLLLVGLLLDRVP ---DAELDAVVPIGADDVLEYAPVTSQHVGTGLPLRELMAAAITVSDNTAANLLVARLGGP -AQVQAALRELGNPTTRVDRVEPDLNEALPGDPRDTSTPADLGATVQQLVLGDVLAPDRRA -LLQQWLRENTTGDAAIRAGVPEGWEVGDKTGSGGYGTRNDVAVVQPDDGAPLVVVLLTDR -GVPDADADDGLLADATRLVVDQ- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni (strain DSM 14576 / KF-1) TaxID=399795 RepID=B7WWP2_COMTK ---TLSDELAALEIQSQGRFGLYVVDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ -RGEIRLWRKLYYSPAEVVAWSPISEKRAGANMTVQELCEAMVVVSDNTAANVMLEASGGP -AALTQWLREMGDGTTRLDRNEPSLNTALPGDERDTTTPRAMVQSLQKLLLGDVLEGYARA -LLQQWLADSRTGDKRVRSGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus sp. AHMU CJ021 TaxID=2072503 RepID=UPI000CA08C23 ----REAAFERVEREHDVRLGVYALDTGSGRAL-VHRPDERFAYCSTIKAVAAGAVLLVSS ---DERMGQVIPYQQGDLVSHSPVTEAHVGAGLGLDALCEAAVRYSDNTAANLMLTELGGP -AGFQRRLRELGDEVTRSDRYETELNDAVPGDDRDTSTPRALATTLRTLLLGDALTDERRA -VLEDWMSGNATGDELVRAGVPSDWRVVDKSGGGFYGTRNDIAVAFRPDAPPIVLAVLTSR -TERDAGGRAEAVAAAAAVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinoalloteichus cyanogriseus TaxID=65497 RepID=UPI000415D6DA ----REAAFERVEREHDVRLGVYALDTGSGRAL-VHRPDERFAYCSTIKAVAAGAVLLVSS ---DERMGQVIPYQQGDLVTHSPVTEAHVGAGLGLDALCEAAVRYSDNTAANLMLTELGGP -AGFQRRLRELGDEVTRSDRYETELNDAVPGDDRDTSTPRALATTLRTLLLGDALTDERRA -VLEDWMSGNATGDELVRAGVPSDWRVVDKSGGGFYGTRNDIAVAFRPDAPPIVLAVLTSR -TERDAGGRAEAVAAAAAVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. GXF4 TaxID=1096546 RepID=I9CK25_9RHIZ --eAIESALAAIEKRLGGRLGVSAG-TQERVFL-RHRADELFPMCSTFKVLAAACVLARVD -AGTESLDRLVTYGNDVLLSYAPVIRKGLEAGMTVADLCAAALEWSDNSAANLLLTALGGP -QALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAAARA -RLEAWMVASQTGFKRLRAGLPPDWTAGDKTGTGDHGTVNDVAILRPPGRAPILACVYVTG -AQAPTEVVEAAHAEIGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=A0A1H9W2Y1_9PSEU ---TVTGKLRELEKQHNARLGVFAADTGTGRTV-LHRADELFPMCSTFKTIAAAAVLRKDR --DGTLLGKVITYTQSDVDKHGPITGRNLANGMTISALCEATITYSDNCAANLLLRELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD -QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR -KDPTGAADEPLLAKTAELVAATf ->[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI000D867AD2 ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASAQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPASQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9C6B8B ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptococcus suis TaxID=1307 RepID=UPI000CF58A2C ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQA-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5953C0 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cepacia complex TaxID=87882 RepID=A0A1V2XJE8_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A8AHA3_CITK8 ----------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A106E519_9BURK ---AAQAELAALEKASDGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTEGHVDTGMTIGQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIAEKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=A0A135IK59_9RHOB ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTAYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSSLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=2 Tax=Tabrizicola piscis TaxID=2494374 RepID=A0A3S8UC22_9RHOB ---RLAETIDRIEQDLNARVGLVIRDSGSDWSV-SQRADERFLMNSTFKTMLCGAVLHRVD -EGDIDLEERIAIEASDILEYAPVTETMVGNTMSVGALCQAALDMSDNTATNLLIDRIGGP -ESVTAFLREMGDPISRLDRREPEVNTFAPDDPRDTTTPAAMVSTMEMLLTGDALTPQSRT -QLVDWMSDGGVTGALIRASTPEGWHVADRSGSGNF-NRNIVAMVTPPDRDPYFVAIFLSD -ADADFDTRNAAVIALSEAAM--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_55 TaxID=1938861 RepID=A0A285BTZ0_9ACTN ---STPKGLRELEAQHGARLGVFARNLATGRTV-RHRARELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRA -LLTHWLRSNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLTTK -PAQDAARDDVLIRDTAALLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC04657 TaxID=1779145 RepID=A0A150VKE4_9ACTN ------------EDAFDARLGVYAIDTGTGREV-AYRDGERFPYASTFKALAAGAVLRKES ---LSGMERVVRYTEDELVDPSPVTEKHVGTGMTLDALADAAVRHSDNTAGNLLFEELAGP -KGLQAVLRSIGDDVTRMDRIEPELGDWRPGEVRDTSSPRALARDLRAFVLGDVLRAPERE -RLTTWLKTNLTGDETIRAGVPDTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SDREAKPDNRLIARAASVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D4DB5 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPEVNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIATSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. ZJ1313 TaxID=2685869 RepID=UPI00140CC45B ---------VALEERYDARLGIFAIDTHTGETV-EHRADERFAYASTYKALAAAALLARTG ---ERRWEEVVAYDADDLVTYSPVTEQHVGTGLSLQRIAEAAVRESDNTAGNLLLDELGGP -AGFQQALRELGDDVTVAARRETALNDTAPGDRRDTSTPRALAQVLQLYAVGDALRPPARR -TLLSWMRGNATGDTLVRAGVPDGWRVADKSGAAAYGTRNDIAVIEVPGRDPVVMAVFSDR -GTPAAEYDDALVAEAARVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Klenkia brasiliensis TaxID=333142 RepID=UPI000A61D212 --------VDALEAAYAARVGVWALDTGTGQVL-EHRADERFAHASTLKLLLVGLLLDRVP ---DAELDAVVPIGADDVLEYAPVTSQHVGTGLPLRELMAAAITVSDNTAANLLVARLGGP -AQVQAALRELGNPTTRVDRVEPDLNEALPGDPRDTSTPADLGATVQQLVLGDVLAPDRRA -LLQQWLRENTTGDAAIRAGVPEGWEVGDKTGSGGYGTRNDVAVVQPDDGAPLVVVLLTDR -GVPDADADDGLLADATRLVVDQ- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea kentuckyensis TaxID=360086 RepID=UPI000A37FDF4 ----LTGKLRELERQHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTLVAAAILRRDH --DGTLLSKVIHYTMDDCIKYAKITEQNLANGMTVSALCEATITFSDNCAANLLLRELGGP -TAITRFSRSIGDPVTRLDRWEPELNSAEPGRTTDTTSPRAIGQSYARLTLGHALNRADAD -QLTKWLLANTTGDHRIRAGLPAAWRWGDKTGTGQYSTTNDVGIAFPPGRAPIVIAVLSTK -KDPTGGADEPLVVKTAELVAASf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LVG6_ECOLX -----------------------------NAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAHTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIHAGLPTSWVVGDKTGSGDYGTTNDIAFIWPEGRAPLILVTYFTK -PEQKAESRR-------------- ->[subseq from] Beta-lactamase n=1 Tax=Parasphingopyxis lamellibrachiae TaxID=680125 RepID=A0A3D9FD09_9SPHN --------LEGIERRIGGRMGVALVD-DTGTQLrSYRGDERFAMCSTFKLALSAAVLERVD -GGDMSLDDMVSFGEDDLLDYAPVARMHLADGMSVGQMAEAISTLSDNVAANLLLDAIGGP -EAMTEFFRRHGDTVSRLDRREPELNENVPGDERDTTSPSAMAGLVTRLMFEDALGEAGRE -QLAAWAVANQTGDDRIRAGMPEGWTVGDKTGSCGT-AYNDIGIVWPPSGRAFVLTVYVDR -PAAEGAEVDAAIAEIAALAA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI00028DF5BB ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMVWKENHKPVYISIYITG -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A0E3XQA2_MYCCH ------TELASLEKDFGGRVGVYALDTGSGATL-GHRANERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQSDLLEWAPVTSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -EDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007526163 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTSLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007560E62 ---TAQSQLDALEQASNGRLGVAALDTANGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTEVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8JIG1_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLQSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARAGAL----- ->[subseq from] Class A beta-lactamase n=1 Tax=Blastococcus sp. TF02A-26 TaxID=2250577 RepID=A0A367A775_9ACTN -----AGELVALEEQFDARLGVYAVDTGSGRTL-AHRADERFAHASTIKALAVGALLARTS ---AADLQRSVPIERSDLAAHSPVTGTRVGAAMTLQELCDAAVRHSDNTALNLVLQELGGP -AGLDAALEAMGDDVTQVSRTEPDLNSVVPGDPRDTTTPRALANGLRAYAVGLGVDAEDRE -QLADWLRRNTTGDTLIRAGVPGDWVVGDKTGTAAYGTRNDVAVLVPPGRAPIVVAVMSSR -DQLDAAHDDALLAAAARVVVTAf ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A3P6L894_LYSSH -------MFVQLENEFDAQLGVYAIDTETNRTV-EYQPNERFAYSSTFKPFAAAILLKQNS ---LEDLEKVVTYTNDDLVPYSPVTEKHVDTGLTLLKINEAAIRKSDNTAGNLLLEAIGGP -DKFEQALHDIGDDVTQPERYEIELNKFTPGNKRDTSTPRAMATNLKKVALSDFLTDDKRE -LLINWMTGNESGDPLIRAGAPEEWVVVDKSGAGTYGTRNDIAIVWPPNKEPIVIAIMSRH -DIENAEYDDALIAKAAEITL--- ->[subseq from] Beta-lactamase n=5 Tax=Vibrio parahaemolyticus TaxID=670 RepID=S5IYD2_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Act143 TaxID=2200760 RepID=A0A2U3A1X4_9ACTN ------AGLHELEAAHGARLGVFARNIATGRTV-RHRADELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAVTRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRD -LLTHWLRSNTTSGTRLRAGLPASWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLTTM -PAPDAARDDALVRDTAALLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces ochraceiscleroticus TaxID=47761 RepID=UPI0004CC623F ----LSGQFERLEREHDARLGVFARDLATGRTV-RYRADERFPMCSVFKGLAAAAVLRDLD -HHGEFLAERIHYSKKYVTDYAPISSENVAHGMTVAELCAAAVSHSDNGAANLLLRELGGP -TAITRFCRSLGDGTTRLDRWEPQLNSAEPWRTTDTTTPRAIGTTYGRLVVGRALAAEDRK -RLKGWLIANTTNTKRFRAGLPEGWITADKTGGGSYGVANDVGVAWPPGRSPVLLSVLSTT -HAPEGPSDDALVAKTAGLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces longwoodensis TaxID=68231 RepID=A0A124HSA0_9ACTN -----GEEFRTLEQRYGARLGVYARNVRTGRTV-AHRAGERFAMCSTFKAFAAAAVLRDHA --DCAPLDRVIHYPPRDILDNSQHSEDHLATGMTVGQACAAAIQYSDNTAGNLLLRQIGGP -QGLTRFFRSLGDRVSRLDRWETDLNTAVPGDQRDTSTPHALGTSFERLTLGRGLGRTDRE -HLVTWLKGNTTSAQRFGAGLPRDWTLADKTGTGSYATAHDIGIAWTTRHTPLLLTVLSTK -DATDAPVDNDLIRDTAALLA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6B1KM47_9ACTN -------RLADLEREYGARVGVYALATGTGATA-VHRADERFAFCSVFKALAAAAVLHHRS ---LAGLDRRVTYTRADLRSTTPITAQHVATGMTLRQLCDAAVRYSDGTAGNLLMRDLGGP -AKLTAYLRGLGDTVSRMDHYEPELHDVRPKDPSDTTTPRAVATDFRKLLLGTALPAGERG -LLTDWLSHNATGARRVRAGLPKGWRVADKTGTGNYGRANDIAIVRPPRTAPLVLAVMTDR -PGYDAEPSDALIAEATART---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0005EC560D ------ARLADLERAYGARVGVYAVATGTGVTV-VHRASERFAFCSTFKALAAAAVLHHRS ---PGGLDRRVTYTEADLRSTAPVTGKHVDTGMTLRELCDAAVRHSDGTAGNLLMRDIGGP -ARLTAYLRGLGDTVSRMDHYEPELHDVPPDDPADTTTPQAIATDFRRLLLGTALPARERR -LLMDWLSRNATGARRIRAGLPGNWKVADKTGTGNYGRANDIAIVHPPRTGPLVLAVMTDR -PGYDTEPSDALIAEATRRT---- ->[subseq from] Beta-lactamase n=5 Tax=Mycobacterium kansasii TaxID=1768 RepID=X7XTE2_MYCKA ---DLQNRFAELEHRYAARLGVYMPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQYP ---LSHLDKMVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT -SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQVVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR -ASYDAEWSEALVADAARCVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI000CDDF961 ---DLQNRFAELEHRYAARLGVYMPATGTTAAI-AYRADERFAFCSTFKALLVAAVLHQYP ---LSHLDKMVTYTSADIRSISPITQQHVATGMSIGELCDAAIRYSDGTAANLLLAEVGGT -SGFTGYLRGLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQVVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAILSDR -ASYDAEWSEALVADAARCVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A345N8C7_ECOLX -----------------GRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVV----- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter cancerogenus TaxID=69218 RepID=UPI0010C15D9C ----VTDTIQTTEDHIKGRVGFTEIDFLSGKVLgSHRHEERFPMMSTFKVLLCGAVLARVD -KGLEQLERRITYNEHDLDDYSPVTRQHLADGMSVSELCNAAITTSDNTAANLLLSTIGGT -EGLTQFVRSIGDNYTRLDRHEPSLNEALPGDERDTTTPAAMAQTLRKLLNGSLLTIESQQ -KLITWMQEDKVGGPLFRSVLPVGFMIADKTGAGEHGSRGIVALLGPRGKPSRIVILYITN -THSSMNELNEHIAGIGDSIIKHw ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacteraceae bacterium TaxID=2052182 RepID=A0A522RSA4_9GAMM ----AALRLADLERVHGGRLGVAIFDTGSGRRI-ANRGDERFLMCSTFKLLLAAAVLARVD -RGEEELDRRIVFDQSALLDWAPLTKQHVGPPMTIAELCRAAITLSDNTAANLLLANIGGP -AAVTRYARSLGDPVTLLDRIEPELNPY------DMTTPSAMLGDIQKLLLGDALTPASCK -LLTHWMLDCQTGLQSLRAGLPPGWRIGDKTGQWDLGANNDIAIVWPPKRKPLLVTAYYMN -HATDPVGRKAVLAEVGRIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. MSh2 TaxID=1506588 RepID=A0A084DCN4_9BURK ---TAQAELGALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTTFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDALQEPQRT -QLAEWMAVGATGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0004CD8DDB ---RARKELRTLEASFKGRIGAYAVDTATGKTI-TYRSGERFPLLSTFKAIAAAAVLHKAR -TDPGLLNKVVRWTTAELQGHSPVTEKHVKDGLTVARLCEAAITQSDNTAANMLLKQIGGP -AGLTAYFHTLKDPISRLDRWETELNDWSPKEKRDTTTPASMGRDLRAVTTGDALNAKDRE -RLNAWLIANKTGDARIRAGLPKTWTVGDKTGTNSYGAGNDIAVVWPGKPAPVIMSIYTNR -RAVDAAADDKVIADTAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rubidus TaxID=310780 RepID=A0A1H8PQJ4_9ACTN ---STDHAFRELEQRFHAHLGLFVLDTGSGRSV-TYGADRRFAMCSTAKVLAAGALLRQDD ---DADLARTLTYSRSDLLDHAPITSQHVDHGMPLRDVIAAALQHSDNTAENLMLRELGGP -AGLQRAVTALGDTTTHVNRTEPALNEATPGDPRDTSTARALAADLRTLLLGTALPAAHRA -RLTDWMLRNTTGGPYVRAALPKGWKAADKTGSGGHGTRNDIAVAWPPAGAPILVSVLTDR -DDPAAASDDALIATSVRTA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. LaPpAH-108 TaxID=1155714 RepID=UPI00037BE98F ---DVTARLRALEREYDARLGVYARNTRTGRTV-AYRAGEPFAMCSLFKAFAAAAVLRDHS -GAECGLDELIHFPPADILSNSEHSEDYLETGMPVRDACALAIRYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDEVSRLDRWETDLNTAIPGDPRDTSTPYALGRSLERLTLGSALSAADRR -QLVAWLSGNTTSTKRFRAGLPADWTLADKTGTGSYASAHDLGIAWTTRRTPVVLTVLTTK -AEQDAPVDESLIERTARVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075875B9 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia JBK9 TaxID=1395570 RepID=A0A0U3UCF1_BURCE ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPVTESHVDTGLTIAQLCEAMLQAGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDRWEPELNQAAPGDERDTSTPVAMVDTLQRLLLGKTLQEPQRT -QLTEWMAGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -QQADAAVRADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=A0A2K7SPC6_9VIBR ---KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00092C017A ------NELVSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILRRRL -SEPGLLDQRIQYTQSDVLEWAPITSQHVSNGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3CTT7_MYCAS ----LFHQFEQLERRYEGRLGVYVPE----PAI-AYRADERFAFCSTFKAPLAAAVLHRYP ---LDHLDKLVSYTRSDINSVSPVTEQHVDTGMTVRQLCDAAVRYSDGTAANLLLAEIGGP -AGFTAYLRSLGDNVSRLDQLEPELNRDAPDDQRDTTTPHAIAPVFQQLLLGDALPPDKRA -LLGDWMARNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF -VGYDAQPNEAFVADAARIVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Vibrio harveyi TaxID=669 RepID=A0A3A1PWM2_VIBHA ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=bacterium AM6 TaxID=1954209 RepID=A0A244C097_9BACT ------ADFAELEKACGGRLGVTVLDSRTGRRIgGHRQGERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVAVAEKDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVTGGP -AALTAFLRDHGDRVTRNDRYEPDMNRFAAGDPRDTTSPAAMAASLALFAVGDGISAASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDDEQRAAVLAQVGRIA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A104J0E0_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] UPI001442C1CD UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001442C1CD ---ATSRAFAALERTHGATLGVTAVDTGNGRAV-GYRSGERFPFASSNKTFIAAATLQRTT ---TADLGTVIHYTRADLLDYAPITSRFVDTGMTVRELLDAMLRFSDNTAANLLVARLGGP -DAVEQWMRGIGDRVTNVDRVEPDLNEALPGDPRDTTTPAQFAADLRTVVLGKTLEAADRT -LLRNTMLDNTTGDETIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPVIVVVLTRK -DTPDATPDNALVAEAAKVAVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Psychrilyobacter atlanticus TaxID=271091 RepID=UPI000426D91E ------KEITAVEKRLGANVGVAVYDTKDHRIS-EYNGDKRFPLMSTFKTLAAANILYKTD -QRLLSLEKKISIHEDEILSYAPVTKEFVGETMKLNEVCSAAMSMSDNTAANIMLENLGGP -QELTKFLREIGDTTTRIDRIEPELNEALKGDERDTTTPKAIVKTLNKLLYGKVLSNTSKE -QLKKWMMDNKVADNLFRAVLPKKYLIADRSGAGGYGSRGITAVVWSEDRTPIIISVYLTQ -TDATFVERNEAIVQIGDVIFNEy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces gougerotii TaxID=53448 RepID=A0A6A0CPY6_9ACTN ----AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP -TAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDCR -LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ -PEEDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=Q9AL74_CITKO ----------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFESSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus ligniniphilus TaxID=1134413 RepID=UPI0009DA7B5C ----TIEKFEQLEKQYDARLGVYAIDTGTKETV-EFREDERFAYTSTSKALAAAILLKQNP ---ISVLEEIRTFTNEDIVTYSPITEDFVDKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGDLRDTSTPKALAINLEVFGISEYLPADKQE -IFTNWLKGNTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIGIVWPPNREPIIIAIMSSR -NEENASFNDELIAKATKVIVQAf ->[subseq from] Beta-lactamase n=1 Tax=Agreia sp. Leaf283 TaxID=1736321 RepID=A0A0S9PIA5_9MICO -------AFAQLEQEFDARLGVYALDPLSRAEV-AYRADERFAYASTFKALAAGILLKTVP ---DEQLDELVSYGADELLPNSPVTEANVNEGMTLRAVAEAAVRFSDNTAGNIVLERLGGP -EGFTQALRDLGDTTSSSDRIETDLNSAIPGDTRDTSTPRAFALDLATLLTTDALGAAQQS -QLIDWMTGNATGSELIAAGLDAGWSVADKSGAGAYGTRNDIALVWPPSGSPIVLVIMSNR -PTEDAEYDNALIARATEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces triticagri TaxID=2293568 RepID=A0A372M6K9_9ACTN ---ELSEQFRELEKRHAARLGVFARDTATGRTV-HYRADERFPMCSVFKSLAAAAVLRDLD -HDGGFLARRIHYTRDCVDTYAPVTGRNLERGLTVGELCAAAVSESDNAAANLLLRELGGP -TAVTRFCRSLGDRVTRLDRWEPELNSAEPWRRTDTTSPRAIGSTYARLVLGRALDEPDRR -RLTRWLIANTTNTERFRAGLPADWILADKTGGGDYGIANDVGVVRPPHGAPLVLSVLSTK -LDPAGPTDNPLVARAAGLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 2112.5 TaxID=1907386 RepID=A0A419V9Q0_9ACTN ----LAAQLRDLEQQYSARLGVFARDTATGRTV-KYRADERFPMCSVFKTLAAAAVLRDRD ---DDFLGHRIRYTEKYVTDYAPITSKNLANGMTVGELCAAAVSYSDNGAGNLLLGELGGP -AAVTGFCRSIGDGTTRLDRWEPDLNSAEPWRKTDITSPRAIGQTYARLVLGSTLTTADRT -RLTRWLVANTTNGERFRAGLPADWTLADKTGGGQYGVANDVGIVWPPGRPPLVLSVLSTK -FDPEGPTDNPLVAKAAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=A0A2I7K758_9RHOB ---DLAETIHSWETALDARLGVFLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQIEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI00080F3FC5 --sQLNEDISLIEQQTSSRVGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075F13E3 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -KLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella anatolica TaxID=2670374 RepID=A0A2W2AXQ3_9ACTN -----DPDVDELERAHDVTLGVSAANLATGARL-AHRDGDRFPILSVFKSLAAAAVLRDLD ---EDRLAHRVWYPPADVLANSSVTAERVGTGMTVAELCDAAIRFSDNAAGNLLLREIGGP -RGLTTFARSIGDRATRLDRWETELNSAVPGDERDTSTPAALARAFAGLLAGDLLRPRDRR -RLRDWMLANTTSGARFRAGLPADWRLADKTGGGDYGTNNDAGVAWNPAGEPIVIVAMSRR -AEKDAPRVDAALADVARLVAR-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI00062E5371 --sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. ARG-1 TaxID=1692501 RepID=A0A0L6J657_9RHIZ ----ADPALAAIEKRLGGRLGVSAG-TQERVFL-RHRADELFPMCSTFKVLAAACVLARVD -AGSESLARLVTYGNDALLSYAPVIRKGLEAGMTIADLCAAALEWSDNSAANLLLTALGGP -EALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAASRA -RLEAWMVASQTGFKRLRAGLPSDWTVGDKTGTGDNGTVNDVAILRPPGRAPILACVYVTG -AQAPTEVVEAAHAEIGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus subsp. albus TaxID=67257 RepID=A0A0X7JDW7_9ACTN ------RRLRALEREHQARVGVFALNLATGATL-LHRAHELFPICSVFKTLAAAAVLRDLD -HDGTQLSRVIHYTGADVTKHAPVTKDHIDTGMTIRALCDATIRYSDNCAGNLLLRELGGP -TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTAPYAIARTYQRLVLGNALDRPDRA -LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPIVLALFTHK -PTQPTASGDPLVIEA-------- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007E9B0EB ----IDDQIAELERRHHALIGLYAANLDTGRTL-THRPDETFAMCSTFKGYAVARVLQMAE -RGEISLDNRMFVDADALVPNSPVTETRVGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS -QGPKAENLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A2N9CVI9_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMIGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID7909 TaxID=2706092 RepID=A0A6B2ZMX2_9ACTN ----TTARLRELERTHGARVGAFAYNVATGVTV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVIHYTEADCVSDSPVTDTHIASGLSVARLCDAAIGDSDNTAGNLLLRELGGP -QAVTRFARSLGDRVTRLDRWEPVLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium szulgai TaxID=1787 RepID=A0A1X2EH11_MYCSZ ---DLTSRFMELERKYTARLGVFAAATDPSAEI-AYRADERFAFCSTFKAPLVGAVLHQYP ---LTHLDKVITYNSDDIRSISPVTQQHVQTGMTIRELCDAAIRYSDGTAANLLLADIGGT -AAFTGYLRELGDNVSRLDQLEPELNRDAPDDPRDTTTPHAIALVFQQLILGDALPPEKKT -MLTDWLARSTTGAKRIRAGFPAEWKVVDKTGSGDYGRANDVAVVWSPSGAAHVVAIYSDR -AGYDAEPSDAIIAEAAAAIAK-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides salmoniphilum TaxID=404941 RepID=A0A4R8S9H4_9MYCO ------TELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRSL -SEPGLLDKRIQYTQSDIMEWAPVASRHIAEGMTVSELCDATIRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEEQLN--VPDGDLDTSTPLQLVTNLRRLVLDEGLDSQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVADKTGSGFKGETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium setense TaxID=431269 RepID=A0A1A0PTS7_9MYCO ----IDDQIAELERRDNALIGLYATNLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG -RKQISLDNRVFVDPDAIVEYSPVTEPRAGGEMTLGELCRAALQQSDNTAGNLLLKTIDGP -PGITAFARSIGDQRTRLDRWETELNSAIPGDPRDTSTPAALAGGYREILAGDALSPPQRR -QLQDWMRANET--SSVRAGLPEGWTTADKTGSGDFGSTNDVGIAYGPDGQQLLLAVMTRS -QADDPKADNPLIGELA------- ->[subseq from] Beta-lactamase n=1 Tax=Rubidibacter lacunae KORDI 51-2 TaxID=582515 RepID=U5DDY1_9CHRO ---DLIAAVQQIEARLNARIGIAVIDKETDRNW-RYHAGDRFPINSTYKTIACAALLSRVD -SGQEQLDRIVIFDESQLADYSPVTETRVGAPMSLGELCQATIATSDNSAANFVMQAIGGP -QAVTQFMRSIGDRTSRLDRWSPELSESVPGDQRDTTSPNAMAMMLEQLVLKGTLSFESRQ -TLESWLKGNEISGDLIRAAVPSDWDVIDKTGSGGYGSRSIAAVMWPPQREPVIAAIYITE -TEVSFAERNAAIAEIGEAIV--- ->[subseq from] Beta-lactamase (Fragment) n=5 Tax=unclassified Rahnella TaxID=2635087 RepID=D7PIH7_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLTKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MBT76 TaxID=1488406 RepID=UPI0009A012D8 ---RVSRQLRELEREHSARLGVFARNMATGRTV-VHRAGERFPMCSTFKTLAVAAVLRDLD -HDGTFLAKRIHYTADYAKAYDKITGKNVANGMTVEELCGAAISYSDNAAANLLLTELGGP -TAVTRFCRSVGDGTTRLDRWEPDLNSAEPDRITDTTTPRAIGRTYAQLVLGNALDPADRK -RLTGWLLANTTSDQKFRAGFK-GWTVADKTGSGSYGTSNDVGVVWTPKGSPVVVSVLTTK -HEPKAAGDDALVRKAAELL---- ->[subseq from] class A beta-lactamase n=1 Tax=Devosia submarina TaxID=1173082 RepID=UPI000D350737 -----VEVAAALEEKLDARIGLTVYDLDNQNTW-DYRADERFPMASTFKAMACAALLSRGE ----TVMNTAVEIAASDLVTYSPVTEALVGQSVPASELCDATMRTSDNTAANKVLQVLGGP -EAVTQFLQTIGDVTTRLDRWEPDLNQGTPGDLRDTTTPKAIARSLHDLVLGNKLDGVARK -QFTAWLLSNKVGDPLLRAGIPPDWRIADRTGAGGHGTRGIIAVMWPPNRAPLVAAIYITE -TAASMEERNTAIAEIGAALA--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A0H2XWP9_BURCA ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000BE396EE ---SLDTKLDALEARYSTRIGVTAIDPATGQIY-QHRGDERFALCSTFKTYAAAEVLRRTR -AGTSSLDKPVLVEPGDLVENSPVTAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP -PAITSLAREIGDESTRLDRWETELNSALRGDPRDTSTPKELADGYQALLLGDALRSPERA -QLVDWMRASKTSDKRIRAGLPDGWTAAAKSGAGRFGTVNDAGVAWDRDGNPLVLAILTDS -LTEDAQGNNQVVADTTAAVVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardia sp. SCN 73-27 TaxID=1660132 RepID=A0A1E4P5Q9_9PSEU --------FDDLEARFGARLGLWARDTGSGAEV-AHRADERFAFCSTFTMLAAAAVLRDVA ---PDRLDAVVHWSPADLMASARITRARVTTGMTLRELCDAAVRFSDGTAGNLLMREVGGP -AGLTAFARGIGDDVTRVDRSEPDLAQGAPGDERDTSSPRASGQDMQRVVLGDALAPDRRE -LLQDLLVRNTTGDARVRAGVPEGWRVADKTGTGGYGTANDVAVVWPPGRAPIVVALMSTK -AQRYADVDEALLAEAAGRVATAf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MR_MD2014 TaxID=1561023 RepID=A0A0N7A303_9MICO ---ATSRAFAALEERDDARIGVVAIDTADGSSV-GYRADERFAFASTNKAFIAAAVLDASS ---GEDLDEVVHYGRGDLLEYAPVTRRYVDEGMTLRALVDAAVRESDNTAANLLVERLGGV -GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDQRDTTTPAQSASDLRAVLVGDALDAGDRE -LLRSSMAGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVVRPPGRDPVVLVVFTAH -ERADAEPSDALVAAATRLAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=A0A2L2KDY8_9VIBR --sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI000758B4F7 ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPERA -QLTEWMTGGARSATGIAAGVPPGWRIADKIGSGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATSAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. rimosus TaxID=132474 RepID=A0A0M8R2P9_STRRM -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHERFPMCSVFKTLAAAAVLRDLD -HDGSQLSRVIRYTEADVTKHAPVTKDHIGTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PTPTAPGDTPLIIKLATV----- ->[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. KX64203 TaxID=1817793 RepID=A0A154C5J6_9GAMM ---ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -QGQESLDRRLLVSRKDLVGWSPVTGKRTGEGMTVAELCEAAVAWSDNGAANLLIKSFGGP -GALTDFLRESGDPVTRLDRLEPELNGYGPDGEYDTTSPAAMLETLHRLLFGEVLSAHGRA -QLAAWMIANKTGDRRLRAGFPANWLVADKTGTSGLGYSNDVGVAWSPARGAVLVTVYCEM -PKAEAGIRDRIIAEVAETV---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A2L0SJV6_9GAMM --------FDALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLVAAVLHRAA -QGRLSLDRRVAVRASDLIAHSPVSARHVDKDLGVRDLCRATLTTSDNAAANLLLPLVDGP -AGLTAFLRAQGDAVTVAARYEPDANRFAPDDPRDTTSPAAMAGNLQRFVFGQALDAASRQ -QLADWLIDNQTGDARLRAGLPAGWRVGDKTGSNGRDTSNDIAVLWPRGGSPWVLTVFLQG -SVLDDAGRDAILRRVGEQATT-- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella anatolica TaxID=2670374 RepID=A0A2W2B817_9ACTN ---AVAAALTALEADYQARLGVYAIDTGTGQIV-EHRADERFAFASTHKMLSAAAVLQATE ---PADLEQLVPIDAAEVVGWSPVTEPAAGAGLTLLEIIQAAITVSDNTAANLLFEQLGGP -DGLEAAVRGFGDATTSFDRIEPDLSEWAPGETRDTTTPRAMAANVEGLLLGDLLADEDRA -LLHDTMRANTTGDELIRAGVPAGWLVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR -LDPDAESDPALIAAATAIVVDE- ->[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T426_9BACT ---ALNQTLAELERVSRGRLGVTLLDTGNGQTS-SYRGDERFLMLSSFKTLAAAYVLARSD -KGEDQLNRRVPITEADLLDYAPITRLHIGQQMTLAELCHATITTSDNTAANLILRSYGGP -QALTRFLRSLGDNVTRHDRYEPALNQMSPVEPMDTTSPNAMSNTLNTLLFGTALKSESRQ -LLWSWLVANTTGDRRLRASVPSDWIVGEKTGTARI-GANDVGFLQAPGSSAVIVSVYLET -DALAAPERDQIIAEVGRRVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanicella sp. SM1341 TaxID=1548889 RepID=UPI000E48A7CB ---RLDDTVRRIEQSLGARVGLMVRDTGSRREW-SHRAAERFAMNSTMKVPLCAAVLHAAE -AGALDLDTPLDIAQEDMLEYAPVAARHVGGSLPVRDLCLAALDMSDNTATNLLIDHLGGP -QEITAFLRGIGDEASRADRREPGLNDVPPGDERDTTTPQAMAGTLEALLLGEALGAGARE -QLLAWMTPGSVTGKLMRAAVPEGWVVADKSGSGST-TRNLVGLVMPPARAPVVFAIFLSG -AEADFATRDKAVAEISAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio campbellii (strain ATCC BAA-1116 / BB120) TaxID=338187 RepID=A7N8N9_VIBCB ---KLNEDISAIEEHISGRIGVSVWNTQTDDHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEATMLMSDNTAANIVLRSIGGP -RGVTTFLRSVGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQIIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis balhimycina DSM 5908 TaxID=1081091 RepID=A0A428WDT2_AMYBA -----QPDFAPLERDFDARLGVYAVDTGTGREL-AHRADERFGYASTHKAFSAAAVLQRTS ---IEGLAKVLTYTRADVPANSPVGEKHVESGLSLRDAIDAALRYSDNTAANLLFRELGGP -AGLAAALRGIGDTITHVDRIEPGLNDLAPGDIRDTSTPHAMAADLRAFTLGTALPPEQRA -LLTDTMRANLTGGALIRAGTPAGWAVADKTGTGEYATRNDIAVVRPPGRAPIVLVVMSDR -KTEDAGHDDRLIAQAAGLALDSf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 2224.1 TaxID=1881020 RepID=UPI00089D883A ----LAAQLRDLEQQYSARLGVFARDTATGRTV-KYRADERFPMCSVFKTLAAAAVLRDRD ---DDFLGHRIRYTEKYVTDYAPITGKNLANGMTVGELCAAAVSYSDNGAGNLLLGELGGP -AAVTGFCRSIGDGTTRLDRWEPDLNSAEPWRKTDITSPRAIGQTYARLVLGSTLTTADRT -RLTRWLVANTTNGERFRAGLPADWTLADKTGGGQYGVANDVGIVWPPGRPPLVLSVLSTK -FDPEGPTDNPLVAKAAALVA--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Rahnella TaxID=34037 RepID=D7PII7_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PQKDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Tr-862 TaxID=2608331 RepID=UPI001419BBBE ---AAQAELAALEKASNGRLGVAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTVFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQLLLLGDTLREPQRA -QLTEWMTGGTRGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PSADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces recifensis TaxID=67355 RepID=UPI000A3CE885 ------PELAALEKRYGARLGVYAHNTRTGATV-AYRADEPFAMCSTFKAIAAAAVLRDHG --GRTALGEVIHYPPADILSNSEQSKAHQQTGMALGDVCAAAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDRVSRLDRWETDLNTAVPGDPRDTTTPRALGRTFELLTLGRALSDGDRG -QLVGWLRGNTTSGKRFGAGLPSDWVLADKTGTGSYATANDLGVAWTGKGTLLLLSVLSTK -PAPDAPVDEALIEETARLLA--- ->[subseq from] Beta-lactamase n=3 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A2X1I0P0_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 348-Celery TaxID=678975 RepID=D7PIJ7_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLTKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoflavus TaxID=35619 RepID=A0A0L8MSV8_9ACTN ------RRLRALEREHQARVGVFALNLATGATL-LHRAHELFPICSVFKTLAAAAVLRDLD -HDGTQLSRVIHYTGADVTKHAPVTKDHIDTGMTIRALCDATIRYSDNCAGNLLLRELGGP -TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTAPYAIARTYQRLVLGNALDRPDRA -LLTDWLLRNTTSVERFRKGLPKDWKVADKSGGGSYGTSNDVAIAWTPDGAPIVLALFTHK -PTQPTASGD-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Gordonia sp. NBRC 107697 TaxID=2589738 RepID=UPI00137B2DD2 ---QVHDEFARLEDRYGARIGVHAVDVGTSAVV-AHRPGETFAMCSTFKTYAAARVLQLVD -AGEADLNREIPIVPDDIVVNSPVTSQAVGQTMSLRDVCAAALERSDNTAGNLMLRLIGGP -AAVTCFARGIGDDASRLDRWEPELNTAEPMDHRDTTTPRALGAGYRRLLVGDVLPPAQRT -QLLDWMRANTTSAKRFRAGLPAGWTSADKSGAGDYGSTNDAGLLIGPTGQRVLAVVLVRS -RGPDAAPFNEAIAESTRLVLTH- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C3ED3 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKIGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MR_MD2014 TaxID=1561023 RepID=UPI0009DE058D ---ATSRAFAALEERDDARIGVVAIDTADGSSV-GYRADERFAFASTNKAFIAAAVLDASS ---GEDLDEVVHYGRGDLLEYAPVTRRYVDEGMTLRALVDAAVRESDNTAANLLVERLGGV -GGVSRWLRGIGDDVTRVDRVEPDLNTAVPGDQRDTTTPAQSASDLRAVLVGDALDAGDRE -LLRSSMAGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVVRPPGRDPVVLVVFTAH -ERADAEPSDALVAAATRLAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces laurentii TaxID=39478 RepID=A0A169PSU3_STRLU ------RALAALDREHAARLGVFARNMVTGAQV-SYRAGEPFPICSVHKVVTAAAVLRDLD -RDGEFLARRVRYSHQDVADYGPVTGEHIADGMTIAELCAATLQYSDNAADNLLLRELGGP -TAITRFCRSLGDRVTRLDRWEPALNSAEPGRVTDTTSPAAFAYTLTGLLLGEVLTPRDRH -RLTAWMRGNTTGTARLRAGLPPDWTLADKTGTGDYGTTNDAGVAWTADGTPVVLSVLSTR -PHPDAAADELLLARTATLLA--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas TaxID=40323 RepID=A0A4Y5QB88_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAAKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. Root1240 TaxID=1736437 RepID=A0A0Q7AAV4_9RHIZ -----TAAARHMERQLGGRLGLMVVDTQTDRHW-AYRADERFAMASTFKALACAALLDAG- ---EAVQGRSMTIDAKDLQTYSPVTGKKVGTAMTAAELCAVTLATSDNTAANLVLEALGGP -KRVTAFLRSAGDMVTRLDRTEPTLNEAKPGDPRDTTTAQAMVTTIGDLLLGDTLSADARG -RLTAWMEANAVADGLLRAGVPKDWRIADRTGAGGHGTRGIVAVMWPPGRLPVVAAIYVTE -TEASMATRDAAIAEIGRVIAA-- ->[subseq from] class A beta-lactamase n=2 Tax=Streptomyces rubidus TaxID=310780 RepID=UPI0009A0C00D ---STDHAFRELEQRFHAHLGLFVLDTGSGRSV-TYGADRRFAMCSTAKVLAAGALLRQDD ---DADLARTLTYSRSDLLDHAPITSQHVDHGMPLRDVIAAALQHSDNTAENLMLRELGGP -AGLQRAVTALGDTTTHVNRTEPALNEATPGDPRDTSTARALAADLRTLLLGTALPAAHRA -RLTDWMLRNTTGGPYVRAALPKGWKAADKTGSGGHGTRNDIAVAWPPAGAPILVSVLTDR -DDPAAASDDALIATSVRTA---- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=UPI0013759E37 --------FDALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLVAAVLHRAA -QGRLSLDRRVAVRASDLIAHSPVSARHVDKDLGVRDLCRATLTTSDNAAANLLLPLVDGP -AGLTAFLRAQGDAVTVAARYEPDANRFAPDDPRDTTSPAAMAGNLQRFVFGHALDAASRR -QLADWLIDNQTGDARLRAGLPAGWRVGDKTGSNGRDTSNDIAVLWPRGGSPWVLAVFLQG -SVLDDAGRDALLRRVGEQAAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Luteimonas huabeiensis TaxID=1244513 RepID=UPI000465C107 -----ATDLAALEAASGGRLGVALLRAGDGAPRlAHREGERFPMASTFKFLLAAAVLARAD -AGALSLDRRLPVRAADLLAHAPATGRHVGRDLTVRDLCRGTMVWSDNPAANLLLPLVGGP -EGLTAFLREHGDAVTECARYEPEVNRFAPGDPRDTSTPAAMAANLQRFALGDALAPASRA -QLADWLIDNRTGDGRIRAGVPTDWRVGDKTGGTR-GVSNDIALLWPPGGTPWLLACYLQG -SPLPAEARDDVLRRAAELAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces niger TaxID=66373 RepID=UPI000ABCC053 ----VTEQFRALERQYEARLGVFARNMATGRTV-RYRAAERFPMCSVFKGLAAAAVLRDLD -RDGEFLARRIHYTRADVEKHTPVTGKNLAHGMTVEALCAATVGESDNAAANLLLRELGGP -TAITRFCRSVGDGTTRLDRWEPELNSAEPWRRTDTTSPQAVGTTYARLLLGRVLTAPDRE -RLTGWLVANTTNTERFRAGLPADWVLADKTGGGDYGVANDVGVVWPPHGAPLALSVLSTT -YDPAGPAKNPLVAKVAELVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB93_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAAKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI0012453F88 ----AQTELAALEKASNGRLGVAALDTSTGTRI-AHRARERFPLCGTYAVVAAAAILARGT -LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHDSGDTTFRLDHWEPELNRAAPGDERDTSTPVAMADTLQRLLLGDTLREPQRA -QLIEWMAGGARGAAGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429FIY0_9PSEU ------ADFEQLERTYRARLGVYAIDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---VAELDRTVTYERKDLVVNSPVTEKHVATGMPLRAVLDATLRYSDNTGGNLLFRELGGP -EGLNAVLRGIGDTTSHADRIEPELNDTAPGDTRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRASTTGDQNIRAGVP-GRPVADKTGTASYGTRNDIGVVWPPNRAPIVLSVLTDR -SEKDAKIDNKLLADATAAAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0005DE2254 ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVTRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAAIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAATRIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI00040C59E3 ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCEAAITRSDNTAANLILERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TDADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=A0A1I6FI35_9PSEU -------ALFELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSTITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDAGGP -AELTKYLRGLDDTETRMDRIEPGLTSAVPGDPRDTATPRSLGTDYQRIVLGDALEPEKRD -FLRDLLERSTTGAKRVRAGVPQGCRVANKTGTGEYGTVNDIAVVWPPNREPVLIAIMSSK -SAADAKYDEALVAEAAAYVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. IB201691-2A2 TaxID=2561920 RepID=A0A550HLV3_9ACTN ---SLSGQLSDLEREYSARLGIFAHDTATGRTV-AHRADERFPMCSVFKGLTAAAVLRDLD -RDGEFLARRIRYTKEYVTAYAPITDENVANGLTVEELCSAAVSESDNGAANLLLRELGGP -TAITRFSRSTGDRITRLDRWEPELNSAEPWRKADTTSPRAIGQTYARLVIGRALPSEDRE -RLTGWLIANTTNTERFRAGLPSDWILADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK -YAADGPTENPLVARAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis xinjiangensis TaxID=124285 RepID=UPI00034CAE93 -----EEAFTGLEEEYDARLGVYALDTGTGQEV-EYGADDRFAYASTFKALAVGALLDQHG ---AEVLDERMDLSEEDLLEYAPIAEEFLGEGMTLREASDATVRYSDNTAGNLVLERLGGP -EGFQEALREIGDDTTNADRWEPDLNEAVPGDERDTSTPRAMAQSLHTYVEKETLAEDERE -FLTDLLVRNTTGDDLIRAGVPQDWEVGDKSGGGRYATRNDIAVAWPPESDPVVIAVMSSR -EEEEAEYDDALVAEATEAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=A0A0L8QR53_9ACTN ---DLSRQLRALETEYKARLGVYALDTATGATV-SYRAAERFPMCSVFKVLTAAAVLRDLD -RDGEFLAKRIRYTEKIVKKYTPVTGKNIANGLTVEQLCAAAVSESDNGAANLLLRELGGP -TAITRFCRSIGDKTTRLDRWEPELNSAEPWRETDITTPGDIGKTFARLIVGRALPSEDRK -RLTGWLVANTTDGERFRAGLPADWILADKTGGGQYGVANDVGVVWPPKRSPLVLSVLSTK -YDPKGPTDNPLVARTAALVADH- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium komanii TaxID=1566885 RepID=UPI000B12AAF0 ---QLGDRLGEMERSHNALIGVFAVNLDTGRTV-AHRAQDPFSMCSTFKTYAAARVLQKAE -RGELALTDRVTVEQSDIVPNSPVTGEHAGQTMTLAELCEAALQQSDNAAGNLLLRTIGGP -SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEAIGGGYRSLITGNVLGEPQRR -QLDDWMRANRT--SSVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT -AAADVPNDRQMVGEVGSMLVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus lehensis TaxID=300825 RepID=A0A4Y7WMI7_9BACI ------AVFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLC ---LDELDTQILFSEADLVTYSPVTEQHVETGMSLHEISDASIRYSDNTAANLIFNEIGGP -SGFKEALREIGDEVTEPERMETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGEALIRSGVPKGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIADATEAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI000C25A439 ------DELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis acidiphila TaxID=715473 RepID=A0A558A8C9_9PSEU --------FAALEKQFGGRLGVAALDTGSGATT-GYRAGERFLMCSTVKALLVAAVLQRSS -ADPALLDRRIRYTRADLIAHSPVTASRLADGMTVAELCEAALTVSDNAAENLLSAQFGGP -AAVTAFLRALGDPLTSSDRTEPALNDSALGDLRDTTTPSWFVRDLQRVALGTALTEGQRG -RLTGWMTACTTGAAQIRAGVPAGWQVADKTGSGSAGESNDVGIVRPPGRAPIVLAIFTAP -ASKDDTTGNPTIAAATRIAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A2Z5N140_BURPY ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYDVVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDMLQRLLLGDALREPQRA -QLTEWLVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. GV104 TaxID=2135679 RepID=A0A2T5XA81_9RHIZ ----AGAALARIARDIGGRVGIAVLDTGGGPAL-LHDAEGTFPLCSTFKLPLAAAILARVE -AGRERLDRRLAYGEADLDSYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLGALGGP -AALTAWCRALGDPATRLDRTEPDLNSAVPGDPRDTTRPAAMAATVETILLGPSLTEAGRA -RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAVYLTG -SEATSEARDAAHAAIGRVIATIy ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=unclassified Rahnella TaxID=2635087 RepID=D7PIK8_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAK----------------- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-6 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A451ENM0_ENTCL ------EQMRELETSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ -DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLNNIAFGSVLDAKNKS -LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR -PNQNDKHDETVIKNAAKIAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_35_23 TaxID=1798274 RepID=A0A1G0G0W3_9GAMM -----QTQLDQLEKSFGGKIGVYAIDTNTNQII-MHHADERFPVQSTMKLIAVAALLKQSD -KDANLLQEKIHYSEKDLTYWHPVTGQNVTAGMTLEALSEAAISYSDNVAANIIIKKLGGP -QAVTAFAHSIGNPSFNVEHYEGNLNSN-PQNTEDTSTPKDMAISLQKLTLGDVLTSAQRT -QLVTWMRNNTTSYKRMRAGVSVGWTVADKTGSGDYGIANDIGILWSPSCKPIVLAVYTVR -NKQDAKSQDDIVAATTSTVLETf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 362-Apple TaxID=678977 RepID=D7PIJ9_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVSLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Amnibacterium setariae TaxID=2306585 RepID=A0A3A1U386_9MICO --qALQRELDDLEARYGARLGVTAIDTGTGRRL-THRADERFAFASTNKAFIAAATLRSAS ---AADLDAVVRYARSDLLASAPITSRHVDTGMTVRALLDAAVRYSDNTAANLLVRRLGGT -AAVERFLRSIGDRTTSVDRLEPDLNTATPGDERDTTTPAASARDVEAVLLGSALPRERRA -VLDDLMTRSSTGGLYIRAGVPAGWAIADKTGSGAHGTRNDIAVLRPPGRAPIVLVLLSRR -VAEDAASDDALLADATAAVVR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ISID311 TaxID=2601673 RepID=A0A5C6WDY5_9ACTN --dELSRRLTDLEQQHSARLGVFAHNPATGRSV-VHRADERFPMCSLFKTLAAAAVLRDLD -HHGEFLAKRIRYTTKDVRKYAPVTGTNLARGMTVADLCAAAISYSDNAAGNLLLRELGGP -TAITRFCRSTGDRITRLDRCEPELNSAEPSRITDTTSPRAIGQTYARLTLGTALTPKDRK -RLTDWLRATTTSGEKFRAGLPSDWAVADKTAGGKYGTNHDVGLTWPPGRSPIVMAVLTTK -REPDATADNPLVAKTAALLAK-- ->[subseq from] Beta-lactamase n=1 Tax=Acrocarpospora macrocephala TaxID=150177 RepID=A0A5M3WV95_9ACTN ---------------------MYALATGTGATV-TYRADERFAFCSTFKALAAAAVLHQNP ---LSHLNKRVTYTSAEVNSISPITENHIGTGMTIRQLCDAAVRYSDGTASNLLVRDIGGP -AQLTAYLRGLGDTVSRMDNYEPELNSNPPRNPRDTTTPRAIAADYHKLVLDDALTTGKRA -LLKDWLERNTTGDKRIRAGVPQGWTVADKTGTGNYGRANDIAIVWPPDTAPLVMAIMSDR -SGYSTPHKESLIAEAAARIV--- ->[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio sp. MES5 TaxID=1899016 RepID=A0A231P3B1_9DELT ---ELIEKISQIERLSGGRLGAARLDCATGSLF-TYRGDEAFPMCSTFKVLAAAAVLKLHP ----QKLNNLVHIRPDEIVAWSPVTEKFVNRGIRVNQLCAAALQYSDNTAANLLLGMIGGP -SGLTAFARSLGDSRFRLDRMEPALNSAEPGDMRDTTSPAAMAATLNTLLMGEALPLQHRE -LLRQWLTECATGASRIPAGTPAGWKVGHKTGSGPNGTSNDVGILLPPAGTPVILALYLTQ -CAAAANDRDATLAATTSL----- ->[subseq from] class A beta-lactamase n=1 Tax=Frondihabitans sp. Leaf304 TaxID=1736329 RepID=UPI000A079FD8 --qSTRAEFSALENKYGARLGVFAVDTSSEKTI-AYRPGERFAFASTYKALAAGILFKQST ---EDELDHTIHFTESDLVDYSPVTEKHVASGMTVREIIAAALQYSDNTAANLMLDQLGGP -AGLTESLRSLGDTTTSVDRPEPGVNEAIPKDPRDTTTPAAIAGDLRSFLLGGALAAPRRA -EMTTLMLGNTTGAPWIRAGVPSTWKIADKTGNASYGTRNDIAVAYPPGRAPIVIALLSDR -GTVDATSDDGLLADATRIVV--- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-7 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A455W340_ENTAS ------EQMRELETSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ -DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLNNIAFGSVLDAKNKS -LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR -PNQNDKHDETVIKNAAKIAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter sp. R17 TaxID=2484250 RepID=A0A3N2QZS9_9ALTE --eDLSDTVEQVEDQLDARVGLAMTDTGSDFSW-SHRADERFLMNSTMKVPLCGAVLAQVD -AGKMSLSDELPVHQDDILSYAPVTKERVGQSMTLDELCYAALDMSDNTATNLLIRHLGGP -EAVTQFLRRIGDSVTRSDRYESALNTWEPGDPRDTTKPVVMIDTLQKLLLGDALTTSSRD -QLVAWMSHGGVTQALLRDDAPSSWKIADKSGSGDH-NRNIVALITPDDGDPRIVTIYISD -TDADFKARNAALKELGAAVIR-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00066A1968 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDGTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Pasteurella multocida TaxID=747 RepID=Q83ZX4_PASMD --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGRSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium parafortuitum TaxID=39692 RepID=A0A375YJZ1_MYCPF ----AQDRIAALGQRHNAQIGLYAANLDTGDSL-AFGDTERFAMCSTFKAYAAGAVLQRVQ -QGALRLGDTVPIRAEDIRPHSPVTEPWVGTEMTLAELCQAALQQSDNAAANALLGVLGGP -PAITEFARGIGDDQTRLDRWEVELNSAVPGDPRDTSTPRALGTGYRALLTGDVLEPAGRQ -QLTDWMLANQT--SSMRAGLPQGFTSADKTGSGDYGTTNDVGVVFGPDGQRLVVAVMTRS -ITPDAPSLRPLIGELATLVL--- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=A0A2S1LUM6_CITKO ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKAQALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium parafortuitum TaxID=39692 RepID=UPI00138D9582 -----QDRIAALGQRHNAQIGLYAANLDTGESL-AFGDTERFAMCSTFKAYAAGAVLQRVQ -QGALHLRDTVPIRAEDIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANALLGVLGGP -PAITEFARGIGDDQTRLDRWEVELNSAVPGDPRDTSTPRALGTGFQALLTGDVLEPAGRQ -QLTDWMLANQT--SSMRAGLPQGFTSADKTGSGDYGTTNDVGVVFGPDGQRLVVAVMTRS -ITPDAPSLRPLIGELAALVLA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752FC89 ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLIGTANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU18528 TaxID=2015350 RepID=A0A2G1SBE3_9BURK -----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PEATAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces malaysiense TaxID=1428626 RepID=A0A1J4Q7K2_9ACTN -------ELADLERRYGARLGVHARNVRTGQVL-AHRAGERFAMCSVFKAFAAAAVLRDEA --RCAPMDKVIHYPPHDLLPNSPRTEENQPTGMAMAEVCAAAIQYSDNAAGNLLLRQLDGP -AGLTRFFRSLGDGVSRLDRWEPELNTAVPGDPRDTTTPGAVAASIERLALGRALAAPDRE -RFVAWLKGNTTSGTRFRAGLPVGWTVADKTGTGDYASANDVGVAWTTRRTPVVLAVLSTK -EDKDAPVDEALIAEAARIAAR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 130 TaxID=2591006 RepID=A0A552RKB0_9ACTN ----TTARLRELERTHGARVGAFAYNVATGVSV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVVHYTKADCVSDSPVTDTSIASGLSIARLCDAAIGDSDNTAGNLLLRELGGP -QAVTRFARSLGDRETRLDRWEPDLNSAEPGRVTDTTTPAAIARDYARLVLGNALEPRDRA -LLTHWLLNCRTSGTRFRAGLPPEWTVADKTGGGFYGSCNDVGVAWTEEGAPVVLAVLTTK -PASGAAGDHPLVRDVAKALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0011A1379D -----DSEFAALEEQFDARLGVYAVDTGTGREI-EWRGDERFAYASTIKALAAAALLDDVG ---TAGLAKTVEIGASDIIKHSPVTETRVGQSMTLDEICEAALTQSDNAAANFIFAELGGP -QAFDAQLDELGDAGTTVSRIEPDLNEALPGDFRDTTTPRASANNLREYVFGDALDDEEKT -ALTDWMKASQTGDTLVRAQLPEDWTVGDKSGGGMYGSRGDLAVVWPTDGRPIVISVLSSR -DEREADYDDRLIAGAAAAAVDQ- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis methanolica 239 TaxID=1068978 RepID=A0A076MNC8_AMYME -------DFADLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVAYTDADVQPNSPVTKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP -AGLAAVLRDIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGEALPADKRD -LLVGIMRRNKTGTELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPGHAPIVLALMSSR -ATADASYDNKLLAEATSRVMD-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI00068196A7 ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITS -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1B4PZY5_BURCE ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGS -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIAQLCVAMLQSGDKSAANLLMGVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPPGWRIADKAGTGGYGTTTDVAMLWPPSRAPIVMAVSFTQ -PGADAAPRADVVASAARIVA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000CC8ED02 ---QLSEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1Q3L7_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Leifsonia sp. 71-9 TaxID=1895934 RepID=A0A1M3LRJ3_9MICO ----TQRAFAELERTHGATLGVTAIDTGSGRTV-AYRGGERFPFASSNKTFIAAALLQRSS ---DADLDQVVHYTSADLLSYAPITSRFVDTGMTVRELIDAMLRFSDNTAANLLVARVGGP -DAVEQWLRGIGDRTTNVDRIEPDLNEALPGDARDTTTPAQFASDLRSVVLGSALETTDRT -LLRNTMLDNTTGDDTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPIVVVTLSRK -AAPDATPDNALLAAATKTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=UPI000C7BFF2F -------RLRALERAHSARLGVFACDAVSGRAV-VHRADELFPMCSSFKTIAVAAVLRDLD -RDGQFLGSRIRYTEKDVTEYAPITGRNLADGMIVADLCAAAIAYSDNGAANLLLRRLGGP -GAVTGFCRSVGDEVTRLDRWEPALNSAEPGRVTDTSSPRALGRTYARLALGGALDARDRE -RLTGWLLANTTGGKRLRAGLPAGWVVADKTGTGSCGTTNDVAIVRPPDRGPIVMAVLSTK -DDAAAPADEALLAETATVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella aurantiaca TaxID=2530373 RepID=A0A4R5AD73_9ACTN -----AAALAALETDYAARLGVYAVDTGTGETV-EHRADERFAFASTHKMLSAAAVLQATE ---PAELAQVIPFDAADVVGFSPVTEPAVGTGLTLLEVIQAAITVSDNTAANLLFEQVGGP -DGLEAVVRGFSDETTSFDRIEPDLSEWAPGETRDTTTPRAMAANLRGLLLGDLLAEEDRT -LLHDTMRANTTGDELIRAGVPEGWVVADKTGSATHGGRNDIAVIEPPGAAPIVLAVYSNR -LDPEAESDPALIAAATAIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Leifsonia sp. NCR5 TaxID=1978342 RepID=UPI0011799599 ---ATSRAFAALERTHGATLGVTAVDTGNGRAV-GYRSGERFPFASSNKTFIAAATLQRTT ---TADLGTVIHYTRADLLDYAPITSRFVDTGMTVRELLDAMLRFSDNTAANLLVARLGGP -DAVEQWMRGIGDRVTNVDRVEPDLNEALPGDPRDTTTPAQFAADLRTVVLGKTLETADRT -LLRNTMLDNTTGDETIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPVIVVVLTRK -DTPDATPDNALVAEAAKVAVR-- ->[subseq from] Uncharacterized protein n=1 Tax=Frondihabitans sp. Leaf304 TaxID=1736329 RepID=A0A0Q5CHS1_9MICO --qSTRAEFSALENKYGARLGVFAVDTSSEKTI-AYRPGERFAFASTYKALAAGILFKQST ---EDELDHTIHFTESDLVDYSPVTEKHVASGMTVREIIAAALQYSDNTAANLMLDQLGGP -AGLTESLRSLGDTTTSVDRPEPGVNEAIPKDPRDTTTPAAIAGDLRSFLLGGALAAPRRA -EMTTLMLGNTTGAPWIRAGVPSTWKIADKTGNASYGTRNDIAVAYPPGRAPIVIALLSDR -GTVDATSDDGLLADATRIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=UPI000998C1E1 ---DLSRQLRALETEYKARLGVYALDTATGATV-SYRAAERFPMCSVFKVLTAAAVLRDLD -RDGEFLAKRIRYTEKIVKKYTPVTGKNIANGLTVEQLCAAAVSESDNGAANLLLRELGGP -TAITRFCRSIGDKTTRLDRWEPELNSAEPWRETDITTPGDIGKTFARLIVGRALPSEDRK -RLTGWLVANTTDGERFRAGLPADWILADKTGGGQYGVANDVGVVWPPKRSPLVLSVLSTK -YDPKGPTDNPLVARTAALVADH- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075DEFD2 ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRARERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRACVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -AGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1U9YFZ2_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium syngnathidarum TaxID=1908205 RepID=A0A1S1KJ70_9MYCO -----DDGIAELERRNNAFIGLYASNLDSGRTL-THRADEMFAMCSTFKAYAAARVLQMAE -HGEVSLDNRVFVDREAIVPNSPVTETRAGGEMTLAQLCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPSALAVGYRAVLAGDALSPPQRR -LLEDWMRANQT--SSMRSGLPEGWTTADKTGSGDYGSTNDAGIAFGPEGQRLLLVMMTRS -QA-DDPKAEPLIGELTA------ ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9142 TaxID=2184573 RepID=A0A3N8AL89_9BURK ---AAQAELAALETASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVAAAAAILARGS -LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP -QAVTSFAHESGDSAFRLDRWEPELNQVAPGDVRDTSTPVAMVDLLQRLLLGDTLREPQRA -QLTEWMTGGARGAAGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lincolnensis TaxID=1915 RepID=A0A1B1M176_STRLN -----APKFRALEREFDARLGVYALDTGTGRSV-GYQPDDRFAYASTFKALAAGAILRKYG ---TDGIDKVVTYSRDDVVADSPVSENFVETGMSLRGLCAATLWYSDNTAVNLLLDELGGP -DGLEKVLEEFGDDVTEMDRYEPEMSDGTPGDIRDTSTPRAMAESLRAFLLGDALKRDERE -LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGSAGYGGRNNIAVVWPEDGNPIVMAVMSTR -GKQGADRRDALIAKAATVAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Georhizobium profundi TaxID=2341112 RepID=A0A3Q8XLC1_9RHIZ ---RLQEVVSTIEENLDARVGIVVRDSGSDWQW-AHREDERFLMNSTFKSVLCGAVLQRAE -MGELALTETLEIEASDILDYAPVAETRVGESMTIGELCLATLDMSDNTAANLLISRLGGP -QEVTAFMRSLGDSVTRLDRLEPEMNSFAEGDPRDTTTPAAMAASWETMLLGDGLSPASQA -QLIEWMSIGGVTGALLRASTPEDWLVADKSGSGNR-TRNLVAMVTPPDETPYVVSIYLSG -TTADFQARNAAVTEIGAAIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A2I5JVQ1_ENTCL ------AQIKELETVFGGRIGVYLLNTENGKEF-SYRQNERFPLCSSFKVFLAASVLKKTQ -DKSFSLNDTVEYSDRVMEKHSPVSEKYLETGASVQTLAMAAIQYSDNGASNLLMERVGGP -EGLTAFMRSTGDTEFRLDRWELELNSAIPGDKRDTSTPKAVAMSLKNIAFGSVLDAKNKA -LLQDWLQGNTTGNARVRAAVPDKWVVGDKTGTCGYGTANDVAILWPDSNSPAVIAVYTTR -TNQNDKHDETIIKNAAKIAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NAS80.1 TaxID=1680159 RepID=A0A1Q5RIB6_9BRAD ----IEPRLKELEARSGGRLGVAVLNVATGQVI-GNRVDERFAMCSTFKALAVAFVLARVD -RGEERLDRRVVFTERDLVPPFNATKPHVGPEMTIAELCEAAVTVSDSTAANLLLASFGGP -AALTAYLRSLGDPVTRLDRIELDLNIVKPGDIRDTTTPGAMVETLHRLLLGDVLSKSSRA -RLTTWMVEARDATRRLRVGLPAGWRIANKPGTWEKISTNDIGVIWPPDRDPIVLAAYLGE -APGSVKVQEGILADVARIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI0013917B1C ---RLDERFEDLESAYDARLGVYVLDTGSGQDI-TYRADERFAYASTFKILLCAVVLDQHS ---FDDLEELITFSADDLQAHSPITSERVETGMTIRELCDAATRYGDNTAVNLLLDVLGGP -SGLGEALKAAGDDVISVDRYAPELSEATPGDTRDTSTPRALATTLRLFALEDALPEDKRE -LLTEWMVGNLTGEDLIRAGIPDDWTVGDRTGAAHYGTRNCIAIVWPPDRDPILIALLTSR -DTEDAERQDELIVEATEAIVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075E622C -----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAVPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTSDIAVLWPPSRAPIVMAVSFTQ -QEATAAARADVVASAARIAA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI0009386A23 ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRAITAMIWKENHKPVYISIYITG -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Trueperella pyogenes TaxID=1661 RepID=G3K0V2_9ACTO --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGNGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. NEAU-CX67 TaxID=2571143 RepID=A0A4U0Q9W4_9NOCA --qSLDTKLDALEARYATRIGVTVINPATGQIY-QHRGDERFALCSTFKTYAAAEVLRRTR -AGTSSLDKPVLVEPGDLVENSPVTAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP -PAITSLAREIGDDSTRLDRWETELNSALRGDPRDTSTPNELADGYRALLLGDALGSPERA -QLVDWMRASKTSDKRIRAGLPDGWTAAAKSGAGRFGTVNDAGVAWDQDGNPLVLAILTDS -LTEDAPGNNQVVADTTAAVVE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. 136MFCol5.1 TaxID=1172182 RepID=A0A1G5GUM1_9ACTN ---RTARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTIGVAAVLRDLD -RRGEFLARRIRYTAQYVEANSPITGRNLSGGMTVAELCAYSITHSDNTAANLLLRELGGP -GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRGTDTTTPRAVGRTYARLVLGDALVPCDRR -LLTGWLLANTTSGERFRAGLPADWTVADKTAGGSYGGNNNAGIAWPPGRPPVVLAVMTTK -PDRDAPADNPLVARTAGVLA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00111DBF05 ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLGPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_012 TaxID=1898738 RepID=A0A1S2I0E8_9MICO ---ATRQAFAALEARSGARVGVVALDTGDGHAI-GYHADERFAFASTNKVFIAAAVLDAAT ---GSDLDEVVHYDRGDLLSYAPVTRPAVDTGLTVRQLVDAAVRSSDNTAANLLVERLGGV -EAVSRWLRSTGDDVTDVSRTEPDLNTAVPGDRRDTTTPAQSATDLRAVLLGDVLDADDRA -LLLGSMRGTTTGDGTIRAGVDPAWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTSH -PAPDAEPSDALVAEATRTAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A119UUU8_9BURK ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAIAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F58F9E1 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGTRAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A4Q6FN72_9PROT ----LSNDFEKLEHETGGRVGVSAWDVTSGERI-GYRAGERFPFCSTFKTLAVAAALKQGG ------LAKRLHFTADDVKKYAPITTKFVDQGMTVSELSAAAIQYSDNAAVNSLMTHLGGL -QTVNAFARTLGDEVFRLDRWEPELNSAEPSDTRDTTTPDAMTGSVHKILLGDALPPAARA -LILAWHKTNTTGDKRIRAGIPKDWTAAEKTGTCSYGTTNDAGVIWRADGSPIVLTIYFTG -RDKDAKPNDAAVAYVAKIISE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium setense TaxID=431269 RepID=A0A0B2Y181_9MYCO ----IDDQIAELERRDNALIGLYATNLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDPDAIVEYSPVTEPRAGGEMTLGELCRAALQQSDNTAGNLLLKTIDGP -PGITAFARSIGDQRTRLDRWETELNSAIPGDPRDTSTPAALAGGYREILAGDALSPPQRR -QLQDWMRANET--SSVRAGLPEGWTTADKTGSGDFGSTNDVGIAYGPDGQQLLLAVMTRS -QADDPKADNPLIGELA------- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML171200 TaxID=2480816 RepID=A0A4V2HDE8_9GAMM ------KDFAALEQVSGGRLGVTLLEVAAGRRL-GRRQDERFPMCSTFKALLAAHVLSLAD -AGTLSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP -PALTAFLRRQGDAVTRSDRYEPEMNNFAPGDPRDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG -ARVDADQRDAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter inhibens (strain ATCC 700781 / DSM 17395 / CIP 105210 / JCM 21319 / NBRC 16654 / NCIMB 13546 / BS107) TaxID=391619 RepID=I7DZ10_PHAIB ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RSTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTATPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TDADFAQRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria MEX-5 TaxID=396597 RepID=B1SXG5_9BURK ---AAQAELAALEKASNGRLGVAVLDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTVFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQLLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium persicum TaxID=1487726 RepID=A0A657QEK6_9MYCO ---DVQSRFAELEHTYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDKVVTYTSADIRSTSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT -TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQLVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] Beta-lactamase class A n=2 Tax=Solirubrobacter pauli TaxID=166793 RepID=A0A660L350_9ACTN ------AALRRLERRHDARLGVYALDTGTGREL-AYRADDRFPFASTFKALAAAALLREVG ---VDGLRKTVPVE--QLVNYSPVTEQRLGTRMSLNALASAAVRYSDNTAANLLLDELGGP -KGLDAILAEEGDDVTRMDRPEPDLNVWEPGQVKDTSTPRALAGSLRTFVLGDALDAPERA -QLTRWLRTNTTGGALIRAGVPDDWTVGDKTGTGAYGARNDIAVLWPPERDPIVLAIMTRG -RAADAEPDDALVAAAAKATI--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium citreum TaxID=2036 RepID=A0A1C7CEA7_9MICO ----TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAALAASS ---PADLDEVVHYDRGDLLSYAPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV -AGVTRWLRGLGDTTTDVSRTEPDLNTALPGDRRDTTTPAQSAADLRAVLLGDALDADDRS -LLRDAMLGTTTGATTIRAGVDPSWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTAH -GTADAEPSDALVAEATRIAIAH- ->[subseq from] Class A beta-lactamase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=A0A1T3NNX6_9ACTN -------RLRALERAHSARLGVFACDAVSGRAV-VHRADELFPMCSSFKTIAVAAVLRDLD -RDGQFLGSRIRYTEKDVTEYAPITGRNLADGMIVADLCAAAIAYSDNGAANLLLRRLGGP -GAVTGFCRSVGDEVTRLDRWEPALNSAEPGRVTDTSSPRALGRTYARLALGGALDARDRE -RLTGWLLANTTGGKRLRAGLPAGWVVADKTGTGSCGTTNDVAIVRPPDRGPIVMAVLSTK -DDAAAPADEALLAETATVLAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3JVG9_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGE-------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. SolWspMP-SS2h TaxID=1305729 RepID=A0A327ST05_9ACTN ---DLRDALAALEREHGARLGVFAHDTGSGATV-RHRADEPFPLCSTFKPLAVAALLHAGD -----DLSARVHYTDQDVADYAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP -TAVTRFCRSIGDRVTRLDRWEPALNSAEPGRVTDTTSPRALARSYARLTLGDTLAPAHRA -RLTAWLLANTTGANRLRAGLPASWTLADKTGTGSYGTANDAGLARPPHRAPIVLTVLTTK -PTPDAAPDEPLIARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759EE59 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGDYGTTTDVAVLWQPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9KPT7_9BURK ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPALNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA -QLTEWMNGGTRGATGIAAGMPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Curtobacterium TaxID=257496 RepID=UPI0009F3EA21 ---ATRQAFAALEARSGARVGVVALDTGDGHAI-GYHADERFAFASTNKVFIAAAVLDAAT ---GSDLDEVVHYDRGDLLSYAPVTRPAVDTGLTVRQLVDAAVRSSDNTAANLLVERLGGV -EAVSRWLRSTGDDVTDVSRTEPDLNTAVPGDRRDTTTPAQSATDLRAVLLGDVLDADDRA -LLLGSMRGTTTGDGTIRAGVDPAWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTSH -PAPDAEPSDALVAEATRTAVE-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=UPI00084AF2C1 ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSVGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LSF7_ECOLX ---------------------------ADNAQT-LYRADERFAMCSTSKVKAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSCVVGDKTGSGDYGTTNDIAVIWPEGRAPLILVTYFTQ -PEQKAESRRDVLAA--------- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. LHW52907 TaxID=2303421 RepID=A0A372GGY9_9ACTN ---DVTRRLLRLEKARDARVGAYAIDTGTGQVL-AHRADERFPFASSFKVMACAAVLQKAR -RDPGLMDRVIRYDRRDLAAFSPETEKHVGTGMTVAELCGATITKSDNTAGNLLLKEIGGP -RGLTAFFRSLGDTVSRSDRVEPGLNRWRPGELRDTTAPGPWARDLRALTVGDALVPADRE -RLVAWLKASVTGGERIRAGLPGGWTVGDKTGTAGHGNANDIAVVWPPSGAPLIFAILVTR -PDADAEPDDETVAAAARILA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=A0A1E5P1S6_9ACTN ---RISRRLRDLEREHSARLGVYARNMVTGKTV-AHGAHERFPMCSTFKTIAVAAVLRDLD -HDGTFLAKRIHYTAEYAKAYDKITGQNVTNGMTVEELCGAAISYSDNAAANLLLNELRGP -TAVTRFCRSIGDGTTRLDRWEPELNSAEPGRITDTTTPRAIGRTYARLVLGNALAPADRK -RLTGWLLANTTSDEKFRAGFK-GWTVADKTGSGSYGTTNDVGVVWTPKGSPIIVSVLTTK -HEADAAADGALVRRAAELL---- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=A0A0M8YFP6_9PSEU -------HLIELERKFDARLGVYAVATGTGTTL-AYRADERFAFCSTFKGLAAAAVLHRHP ---LSHLDTVVTYTERDLMASSAITRQHVATGMTVRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYVRGLGDTVTRSDRVEPDLTTAVPGDPRDTTSPRAIGVDYREIVLGDALEPDKRA -FLRDLLERNATGTQRVRAGVPQGWTVADKTGTGDYGTVNDIAVVWPPNAAPLLISIMSSK -AAADDGYDQALLAEAAAYAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium aphoticum TaxID=754436 RepID=A0A090QGA8_9GAMM ----VQTQIQAIEQTLSAHIGVAVLDTQNNTRW-SYKGDERTPLTSTFKTLACAKLLHDAE -NNTLALIDTVTIKASELVTYSPVTEKWVGKAIPVVQACEATMFTSDNTAANIVIHAVGGP -DKITAFLRQSGDAVTQLDRLEPALNEATPGDVRDTTTPNAMTQTLNTLLFKEGLSKENQQ -QLIDWMMGNQVTGNLLRSVLPKSWTIADRSGAGGHGARSITAVVWPEDRAPVIIAIYVMQ -TEASFDARNQAIVTIGQAIFNLy ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium kunshanense TaxID=1445034 RepID=A0A328BFB1_9CAUL --------WSALESRVGGRLGVFAINAGTGRSL-GWRASERFPMCSTFKGLLAGAVLARVD -AGREQLDREIPLSEADLVAHAPVTSLYVRAGIRVDTLCKAIVEVSDNPGANLLLKTLGGP -AGFTAWLRTTGDNITRLDRYETELNSAIPDDPRDSTSPMAMVGSYRRLLLGPSLESASRQ -RLAGWMEGASTGLKRLRADLPAGWRAGDKTGSGANNTANDVAILWPPRGAPILVGCFSTQ -ATAP-EARDAVMAHIGRLAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA040 TaxID=1288083 RepID=UPI0004013536 --kRAEQALAQLEERFDARLGFYLLDTGTGREI-THRADERFSYASTFKALAAGVLLGTST ---DEELDRVVRYDESDLLEYAPVTSEHVDTGMTLDALIAAAVQYSDNTAANLMLEELDGP -EGLQKALRDLGDTTTSVDRIEPDLNGFAPGDDRDTSSPRALGTDLRRFVLGDALPEDRRE -RLTDLLLGNTTGDDYIRAGVPDGWRVGDKTGGGGHGTRNDIAVVWPDSGAPLVLAIVSDR -GEEGAASDDALLAEATEA----- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium persicum TaxID=1487726 RepID=A0A498PEK6_9MYCO ---DVQSRFAELEHTYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDKVVTYTSADIRATSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT -TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPHAIALDYQQLVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F593053 ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Lechevalieria xinjiangensis TaxID=402600 RepID=A0A1H9IWT4_9PSEU -----TGRLRELERQHNARLGVFAAETATGRTV-LHRADELFPMCSTFKTIAAAAVLRRDH --DGTLLGKVITYTQADVDKYGPITGRNLAAGMTISALCEATITYSDNCAANLLLRELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALDRADAD -QLTKWLLANTTGGNRIRAGLPAAWRWGDKTGTGKHGTTNDAGVAFPPGRSPIVIAVLSTK -ATPDAPADEPLLAKAAELVAGMf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U9GMV8_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTCMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 2131.1 TaxID=1855346 RepID=A0A1H5CZZ3_9ACTN ----TTARLRELERAHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVVRYTKADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAANLLLRELGGP -AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRG -RLTHWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI0007686F0F -----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAVPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -QEATAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum visakhapatnamense TaxID=364297 RepID=A0A4R8G8Y2_9RHOB --qALADTISRLESALPARIGVAIRDSGSDWGW-GHRDSERFLMASTFKSVLCAAVLDRAD -RGLLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLATLDMSDNTAANLLIARLGGP -QEVTAFLRRIGDPVTRLDRTEPDLNLLDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA -RLADWMSHGSVTASLIRASAPPGWTVSDKSGGGREYTRNLVAMIRAPGRAPVVVAIYLSD -CPADWATRNAAVAEIGAAVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000841975D ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGTRAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A1A0QSD2_MYCPR ----VDDQIAELERRDNALIGLSATNLDSGRIL-THRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDPEALVPNSPITEAHAGSDMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALALGYREILAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDPKADNPLIGELT------- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9G5Z9_9BURK ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=UPI000B87F0A4 -------ALFELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSTITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDAGGP -AELTKYLRGLDDTETRMDRIEPGLTSAVPGDPRDTATPRSLGTDYQRIVLGDALEPEKRD -FLRDLLERSTTGAKRVRAGVPQGCRVANKTGTGEYGTVNDIAVVWPPNREPVLIAIMSSK -SAADAKYDEALVAEAAAYVLK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium neoaurum TaxID=1795 RepID=UPI000B06E39A ---ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAEEPFAMCSTFKTYAAAAVLRRVA -EGELSLDKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP -RAITDFARSIGDDKTRLDRWETDLNSAIPGDPRDTSTPEALGTGYRNLLAGDALPPAQRD -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGSRVLLSIMTRT -QSPDAEGLRPVIGEIAALVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces iakyrus TaxID=68219 RepID=UPI0005251D7F -------RLTDLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRT ---VSGLDRRVTYTEADLRSTSPVTGRHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -PKLTAYVRSLGDEISRMDHYEPELHDVPPGDPADTTTPQAIAADFRRLLLGTALPARERR -LLMDWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTEPLVLAVMTDR -PGRDAEPSDALIAEATRRT---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium kubicae TaxID=120959 RepID=A0A1X1XIU2_9MYCO -----TDRIDELESQYHAFAGVYAQDLDSGHTV-THRADDPFAMCSTFKAYAAGRVLQKAQ -GGELDLDQATFIDPNELQPNSPVTAPHAGHSMPLAQLCAAALQRSDNTAANLLLQAIGGP -PAITEFARSIGDDRTRLDRWEVELNTAIPGDPRDTSTPRALGAGIQNLLAGTVLAPPQRR -QLETWMRGNVT--STMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPNGQRVLLAIMTRS -QAPDADALQPLIADVTRAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. EPG1 TaxID=2064767 RepID=A0A2S7NKQ4_9MYCO -----QDRIAALGQRHNAQIGLYAANLDTGESL-AFGDTERFAMCSTFKAYAAGAVLQRVQ -QGALHLRDTVPIRAEDIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANALLGVLGGP -PAITEFARGIGDDQTRLDRWEVELNSAVPGDPRDTSTPRALGTGFQALLTGDVLEPAGRQ -QLTDWMLANQT--SSMRAGLPQGFTSADKTGSGDYGTTNDVGVVFGPDGQRLVVAVMTRS -ITPDAPSLRPLIGELATLVL--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5C0PCR9_PSEAI --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTDNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces chartreusis TaxID=1969 RepID=A0A5J6JV46_STRCX ----TTGRLRLLEQQHGARLGVFAYNVRTRRTV-THRADELFPMCSVFKTLASAAVLRDLD -RDGEFLGRRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRRETELNSAEPWRVTDTTSPRAIGRTYGRLVLDDALNRPDRR -LLTHWLLSNTTSGKRFRAGLPKTWTVADKTGSGSYGTTNNVGVAWTPDGTPVVLSVLSTK -PAQDAAWDDALVAETAALL---- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ESTM1D_MKCIP4_1 TaxID=2072414 RepID=A0A3S7KUD4_9GAMM -------DFAALEKASGGRLGVTVLDTGSGRRLaGHRQDERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDARDTTSPAAMAASLARFAVGDGLLQASRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRAGTPWVITAYLQG -ASVDEEQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces harbinensis TaxID=1176198 RepID=UPI000B81CAF1 ------GEFARLEDAYDARLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLEEYG ---LAGMDEVIPYGEEDLLPNSPITEERLAEGMSKSDLCDATVRYSDNAAANLLWDTIGGP -AGLQERLAGLGDDVTRMERWETELNEAVPGDERDTTTPEAFAGNLAGYVLGEVLPEPERA -QLTEWLVTNTTGDELIRVGVGEGWTVGDKTGGGGHGTRNDIAVLWPDSGPPLVLAVFSTR -EEPDADWDNALIAEAASVAV--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=unclassified Rahnella TaxID=2635087 RepID=D7PIJ0_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKHSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -QKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGDYGTTNDIAVIWPDNKAPLILITYFTQ -PEKDAK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Alcanivorax sp. EA2 TaxID=2183984 RepID=A0A3D9IKD4_9GAMM ---ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP -GALTEFLRESGDPVTRLDRLEPELNGYGGADESDTTSPGAMLDTLYRLLFGEVLSAHGRA -QLAAWMIVNKTGDRRLRAGFPANWLVADKTGTSGLGYSNDVGVAWSPARGAVLVTVYCEM -PKAEAEARDRIIAEVAEMVS--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI0009925737 ------TELASLEKDFGGRIGVYALDTGSGATL-GHRANERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLMEWAPVTSQHVAEGMTVAELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLALDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium neoaurum TaxID=1795 RepID=A0A024QNI4_MYCNE ---ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAEEPFAMCSTFKTYAAAAVLRRVA -EGELSLDKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP -RAITDFARSIGDDKTRLDRWETDLNSAIPGDPRDTSTPEALGTGYRNLLAGDALPPAQRD -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGSRVLLSIMTRT -QSPDAEGLRPVIGEIAALVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5B32F9 ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces ipomoeae TaxID=103232 RepID=A0A540PZV3_9ACTN ----TAAEFRSLEKEFDARLGVYALDTGTGRSV-GYQADDRFAYASTFKALAVGAILRKYG ---TDGIDKVVRFSRDDVVADSPVSENFVETGMTLRGLCAATLWYSDNTAVNLLLDELGGP -DGLERVLERLGDDVTEMDRYEPDMSDGIPGDIRDTSTPRAMAGSLRAFLLGDALKRDERR -LLRQWMTTNMTGRNLIRAGVPDDWEVADKSGSAGYGGRNNIAVVWPSDGNPIVMAVLSTR -DKQGAERRDALIAKAATVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. URHD0025 TaxID=1298864 RepID=UPI000401E568 -----DGQIAELERRDNALIGLYAANLDSGRTI-THRPDEMFAMCSTFKGYAAARVLQMVG -RGQLSLDNRVFVDRNAIVPNSPVTETHAGAEMTLAQLCQAALQRSDNTAGNLLLKTIDGP -GGITAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDPKADN-------------- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. GA-1199 TaxID=1772287 RepID=A0A101BM29_9MYCO ----IADRLGEMERRQNALIGVFATDLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP -SGVTDFARSIGDQRSRLDRWEIELNAAVPGDPRDTTTPEAIAGGYRSILTGNVLAEPQRR -QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPAGERLLLAIMTRT -AAPDAPNDRQLVGEVASALVA-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBA3_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAAKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -PALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Leifsonia TaxID=2663824 RepID=UPI000375FEDB ---AAARALAELESQYGATLGVYAVDTGTGRSV-GYRQDDRFAYASTSKVLLAGAVLARSS ---DEQLDAVVPYTSDDLVSYSPITETMAGAGMPLRDVIAAALQKSDNTAANLLFRQLGGP -AELEKSLRALGDETTEVERTEPALNEAAPGDPRDTSTPRALAADLRAYALGEELPANRRK -LLVDDMTGNATGDPLIRAGAPTGWTVSDKSGAASYGTRNDIAVLTAPGHAPVVMVVLSRK -ADKDAAYDNALVADTAKVL---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces harbinensis TaxID=1176198 RepID=A0A1I6QZ27_9ACTN ------GEFARLEDAYDARLGVYALDTGSGEEI-GYREDERFAYASTFKALLCGAVLEEYG ---LAGMDEVIPYGEEDLLPNSPITEERLAEGMSKSDLCDATVRYSDNAAANLLWDTIGGP -AGLQERLAGLGDDVTRMERWETELNEAVPGDERDTTTPEAFAGNLAGYVLGEVLPEPERA -QLTEWLVTNTTGDELIRVGVGEGWTVGDKTGGGGHGTRNDIAVLWPDSGPPLVLAVFSTR -EEPDADWDNALIAEAASVAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAA1_KLEPN ------------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIFWR- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=A0A132F6N5_9BURK ---AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS -LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDHWEPELNAAAPGDERDTSTPVAMVDMLQRLLLGDLLREPQRA -QLIEWMVGGARGAAGIAAGVPPGWRVADKAGTGRYGTTSDVAVVWPPSRAPLVMAVSFTQ -PRADAAARADVVASAARIVAN-- ->[subseq from] Beta-lactamase OXY-2 n=2 Tax=Burkholderia TaxID=32008 RepID=A0A088UZM8_9BURK ---AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS -LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDHWEPELNAAAPGDERDTSTPVAMVDMLQRLLLGDLLREPQRA -QLIEWMVGGARGAAGIAAGVPPGWRVADKAGTGRYGTTSDVAVVWPPSRAPLVMAVSFTQ -PRADAAARADVVASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Tistrella mobilis TaxID=171437 RepID=A0A162LGU4_9PROT ---RLADTVSRIEDQLDARIGLVLHDTGRNWRW-GHRADERFLMNSTVKMPICGAILAGVD -AGRISLDETLPIRRADLVSHAPVTRPRVGQAMSIADLCFATLDQSDNPAANLLITRLGGP -AGVTQFFRSIGDPVSRLDRLEPGLNSAPAGDARDTTTPAAMAATMETLLLGTSLSPASRA -QLTEWMRHGGVTGALLRKSAPADWQIADKSGAGDN-TRNLVALITPPGRAPWIAAIYLGD -AETDFATRNKALAEIGAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A1Y5XUI0_KIBAR -------DFKALEARFDARLGVYAVDVTTGKSV-AYRENERFAICSVFKAYAAGALLKAHP -LSSGFFTQTIRFTQAEVVANSPVTSTRVTTGMTVAELCEAAITKSDNTAGNQMLKLLGGP -TKLTDFARSIGDPVTRLDRWETELNVVPRGTEQDTTTPIAIAGAYRDLVVGNVLGEPERK -QLKDWLIANTTGDARIRAGLPSGWVTGDKTGTGSFAAANDVAVTWPSPEKPIVIAILTDK -ADENAKYDNALIAEATKVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. SAI-095 TaxID=2597743 RepID=UPI00135939D5 -------AIAALEQKHQRRLGVWAKNMRTGRVI-EHRADERFPMLSTFKTLLAASILRDHP ---ARTLQQRLTWEAADVVINSPITSLTVRNGLTVAQLAEATITRSDNTAANELLHLIGGP -AGITRFARSLGDSVTRLDRWEPDLNSAIPGDPRDTTSPRAIAQTYTKLVLGDALDRADRD -QLLTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS -DNPTAAPLDTPLADIAATVC--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter nitrogenifigens DSM 23921 = LMG 23498 TaxID=1120919 RepID=A0A511X6X8_9PROT -----PQAIATYERESRGHIGVYAENLATGRKL-LWRADERFVMCSTFKASLAACVLRRVD -RGQEKLDRIIAYTKADVPDYAPVARENLARGMTVAEMCQAAVEQSDNTCATLLLSSIGGP -AALTAFWRSIGDTQTRLEDPEPYLNRTPPGGVRDTTTPSSMAKILQRVALGDVLSDSSRA -LLTGWLVGCQTGANRLRAGLPKTWRVGDKTGNNAKDAAGDIAVLWPKPDAPIIVAVYTRG -GTPTDAQLASAFAGVGALVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=Q7WZT6_CITKO ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKALALSASTQFEPSQLVEYSPITEKHVAPDMNWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAKTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Motilibacter sp. E257 TaxID=2714956 RepID=UPI00140A750F ----ADEEFGELEDAYQARLGVYAVDTGTGREL-TYRADERFAFASTVKALAAGALLQQLS ---DAELDATVEYDTADLVPHSPVTERHVVTNLPWRTVLAAALQQSENTAANLMFARLGGP -AGLQQALRALGDRVTRSDRVEPALNSAVPGDVRDTTTARAIAHDLRELLLGDALQADRRA -LLRAWMTTNTTGGPYVRAGLPAGWEAADKTGSGGHGTRNDIAVVWPPGGAPYVIALMSDR -GVEGARSEDRLLADATRVALE-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=A0A510IBU6_9VIBR ---KLNEDLAAIEQHIGGRIGVSVWDTQNDEHW-DYRGDERFPMMSTFKTLACATMLSEMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSESLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075B063F ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANSVAGIRAGVPFDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas halophila TaxID=29573 RepID=UPI0011BDF169 ---DLDQRLGELERADDDRVGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -EGSETLDRRVVIEEGDLGGWTPITEKRLGEPLTLAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLREIGDDTTRLDRLEPELNTDHAGDERDTTTPLAMMTTLRTLLLGDVLSPSLRH -QLASWMIEGKTGDARLRAGMPSSWLVGEKTGTNGVGNANDIGIAWPGDRGAVIAVAYTRM -PSATAEQRDETIAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kubicae TaxID=120959 RepID=UPI0007FF50E8 -----SDRIDELESQYHAFAGVYAQDLDSGHTV-THRADDPFAMCSTFKAYAAGRVLQKAQ -GGELDLDQATFIDPNELQPNSPVTAPHAGHSMPLAQLCAAALQRSDNTAANLLLQAIGGP -PAITEFARSIGDDRTRLDRWEVELNTAIPGDPRDTSTPRALGAGIQNLLAGTVLAPPQRR -QLETWMRGNVT--STMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPNGQRVLLAIMTRS -QAPDADALQPLIADVTRAVL--- ->[subseq from] SHV/LEN/OKP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010834254 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVALCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGI-------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML171590 TaxID=2527958 RepID=A0A4Q9TBP7_9GAMM ------KDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAE -AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP -PALTAFLRRQGDAVTRSDRYEPEMNNFAPDDPRDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG -ARVDADQRDAVLARVGALA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Methylobacterium sp. WL6 TaxID=2603901 RepID=A0A5C8W7Q6_9RHIZ -------RIGALEARLGGRVGVAFRD-ATGVFL-GHRADEAFALCSTFKVLAAAAILARVA -AGRETLDRRIAYGADDLQSYAPVTRSALDAAMTVGGLCAAAIVRSDNTAANLLLDALGGP -AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPAAITRTLDRCLLGDALAPPHRA -RLEAWMVACETGGAKLRAGLPPAWPVGDKTGSGDNATSNVVAILHPPGRAPILAGVFLTG -SEAPPAARDAAHAEIGRILAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Phycicoccus jejuensis TaxID=367299 RepID=UPI00055D7D88 -----DRAFAALERVHDATLGVTAIDTATGRTV-SWRSGTRFPFASTNKTFIAAAVLDRSS ---DADLDEVVRYTREDLLEYAPVTSRFVDTGMTVRELLDAALRFSDNTAANLLVERLGGP -GAVQAWLREHGDRVTRVDRVEPELNEALPGDPRDTTTPAQFARGLRDVVLGSDLAVGDRT -LLRNLMLGCTTGDATVRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPVVVAVFTRQ -DTPDAEPDNALVAAATREAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID4985 TaxID=2690292 RepID=UPI00136E783F ---HVTAQLRSLEREYDARLGVYARNTRTGRTV-AYRAGEPFAMCSLFKAFAAAAVLRDHG -DGRTGLDEVIHFPPADILSNSEHSKGYLETGIPVRDACALAIQYSDNTAGNLMLRRIGGP -AGLTRFFRSLGDEVSRLDRWETDLNTAIPGDPRDTTTPYAIGRGLERLTLGNALSGADRR -QLVAWLSGNTTSTRRFRAGLPADWTLADKTGTGSYASAHDLGIAWTTRRTPVVLAVLTTK -AERDAPVDESLIERTARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A63BEE ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDSAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB95_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIdGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075814B8 ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLIGSANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. OK519 TaxID=2135729 RepID=A0A2T5KRI3_9NOCA -----DSEFAALEEQFDARLGVYAVDTGTGREI-EWRGDERFAYASTIKALAAAALLDDVG ---TAGLAKTVEVGASDIIKHSPVTETRVGQTMTLDEICEAALTQSDNAAANFIFAELGGP -QAFDARLDELGDAGTTVSRIEPDLNEALPGDARDTTTPRASANNLREYVFGDALDDEEKT -TLTDWMKASRTGDALVRAQLPEDWTVGDKSGGGMYGSRGDLAVVWPTDGRPIVISVLSSR -DEREADYDDRLIAGAAAAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075258C2 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSSVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces ipomoeae 91-03 TaxID=698759 RepID=L1L8R3_9ACTN ----TAAEFRSLEKEFDARLGVYALDTGTGRSV-GYQADDRFAYASTFKALAVGAILRKYG ---TDGIDKVVRFSRDDVVADSPVSENFVETGMTLRGLCAATLWYSDNTAVNLLLDELGGP -DGLERVLERLGDDVTEMDRYEPDMSDGIPGDIRDTSTPRAMAGSLRAFLLGDALKRNERR -LLRQWMTTNMTGRNLIRAGVPDDWEVADKSGSAGYGGRNNIAVVWPSDGNPIVMAVLSTR -DKQGAERRDALIAKAATVAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces swartbergensis TaxID=487165 RepID=UPI000A388583 -------RLADLEREYGARVGVYALATGTGASA-IHRADERFAFCSVFKALAAAAVLHHRS ---LDGLDRRVTYTRDDLRSTTPITAKHVATGMTLRQLCDAAVRHSDGTAGNLLMRDLGGP -AKLTAYLRDLGDSVSRMNHYEPELHDVPPEDPSDTTTPRAIAADFHKLLLGTALPAGERA -LLTDWLSHNATGARRIRAGLPKGWQVADKTGTGNYGRANDIAIVRPPRTEPLVLAVMTDR -PGYDAAPSDALIAEATAR----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. uw30 TaxID=1828179 RepID=UPI0011CE17F9 -----ADRFRELERQHGARLGVFAHNVRTKRTV-THRADELFPMCSLFKTLASAAVVRDLD -HDGEFLARRIHYTEADLPKGSDKTREHLAEGMTVAELCEVAITYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPWRVTDTTSARAIGRTYGRLVLDDALNGPDRG -LLTRWLLSNTTSGKRFRAGLPPTWTVADKTGSGSYGTTNNVGIAWTPDGAPVVLAVLSTK -PAQDAAWDDALVAETARLL---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium conceptionense TaxID=451644 RepID=A0A0J8UC08_9MYCO ----IDDQLAELERRDNVLIGLYASNLDSGRRI-THRADQMFAMCSTFKGYAAARVLQMAE -RGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPSQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium conceptionense TaxID=451644 RepID=A0A0U1DTP3_9MYCO ----IDDQLAELERRDNVLIGLYASNLDSGRRI-THRADQMFAMCSTFKGYAAARVLQMAE -RGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPSQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. OF1 TaxID=2213162 RepID=A0A5P0Z151_9ACTN -----SRRLRALEREHDARIGVFAYDTGTRRRV-LHRADERFPMCSVFKTFAAAAVLRDLD -RDGDFLAKRIRYSRQEADDYAPVTGRNIARGMTVGELCGAAVSESDNAAANLLLRELGGP -RSITRFCRSVGDDVSRLDRWEPELNSAEPWRVTDTSSPRALGRSYARLVLGDALEPGDRT -RLTDWLLANTTNGERFRAGLPADWLLGDKTGAGSYGTNNDAGVAWPPGRAPLVLVVLTTK -FEPDAAPDNTLVRRTAELLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI00075E2457 -----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAVLARGA -LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PEATAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI0008A99EFE ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000668783C -htXAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMIGGARGATGIAAGAPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rifamycini TaxID=31962 RepID=UPI0003F56BAC ---EVGKRLHRLEAERNLRIGAYAIDPATGAFV-SHRADERFPYTSTFKAIACGGVLQKAR -TDPGLMERVIHYTEDDLVEWSPVTKDHVDTGMTVSALCDAAITQSDNTAGNLVMKQLGGP -AGLTRFFRSLGDGISRADRWETALNDWKPGERRDTTVPSVWAANLHKLTVGDVLVPEDRE -QLIAWMKANTTGDKRIRAGLPDSWTIGDKTGSGGYGNANDIAVAWPPGRDPLVMVILTTA -KKVDAEADDAAVAETAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio alfacsensis TaxID=1074311 RepID=A0A347UWX4_9VIBR --tKLNEDLASIEQHISGRLGVSVWDTQTDQRW-DYRGDERFPMMSTFKTLACATMLHAMD -NDKLDRNATAKVEERNVVVWSPVMDRMVGQTTRIEHACEATMLMSDNTATNIVLRSVGGP -KNVTLFLRSIGDKATRLDRFEPRVNEAKPGDSQDTTTPNAMVNTLHTLLEGDSLSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQIIAQISQLVLDEy ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces hainanensis TaxID=402648 RepID=A0A4R4TAJ5_9ACTN ---DTEREFAALEREFDARLGVYALDTGTGREV-AYRADDRFAFASTFKSLAVGAALQRFG ---VEGMDEVVEYAADDIVPNSPVTENFVETGMSLRELSAATLWYSDNTAANLLFDALDGP -EGLEAALEELGDDVTEMDRYEPELSDGVPGDIRDTSTPRALAGSLRAYLLGDALEREERE -LLTTWMATNTTGETLIDAGVPDDWTVADKSGTAGYGGRNDIAVLWPEDGNPIVMAVLSSR -DQEGATRDDALIARAATAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI0008A83CDA ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVTAILHRRL -SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. ATCC PTA-5024 TaxID=316330 RepID=W2EHT3_9ACTN ----VRRELRALEASFRGRIGAYAVDTATGATV-SYRPDERFPLLSTFKALAAAAVLHTAR -TDPGLMSRVVHWTAAEVKPNSPITAGHVEDGLTVARLCEAAVTRSDNTAGNILLKRVGGP -AGLTRYLRSIGDGTTRLDRWETGLNVWSPGERRDTTTPAAVVRDLRALTVGDALTPQDKD -RLNGWLRATRTGDARIRAGLPATWLVGDKTGTGSYGTANDIAVVRPGTGAPIVMAVYTTR -KAAGAPADEKVVAETAAVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=UPI0009EAEEB5 -------HLIELERKFDARLGVYAVATGTGTTL-AYRADERFAFCSTFKGLAAAAVLHRHP ---LSHLDTVVTYTERDLMASSAITRQHVATGMTVRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYVRGLGDTVTRSDRVEPDLTTAVPGDPRDTTSPRAIGVDYREIVLGDALEPDKRA -FLRDLLERNATGTQRVRAGVPQGWTVADKTGTGDYGTVNDIAVVWPPNAAPLLISIMSSK -AAADDGYDQALLAEAAAYAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A7993B ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLK--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-2 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A1Z1CLH6_ENTAS ------EQMRELEASFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKKTQ -DKSVSLDDMMEYSGRVMEKHSPVSEKYRKTGASVRTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS -LLQEWLKGNTTGNARIRAAVPDKWDVGDKTGTCGYGTANDVAILWPDANSPAVMAVYTTR -PNQNDKHDEAVIKDSAKIAIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9A2E5E ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TDADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=2 Tax=Tistrella TaxID=171436 RepID=A0A3B9ITI8_9PROT ---RLADTVSRIEDQLDARIGLVLHDTGRGWRW-GHRADERFLMNSTVKMPICGAILAGVD -AGRISLNETLPIRRADLVSHAPVTRPRVGQAMSIADLCFATLDQSDNPAANLLITRLGGP -AGVTQFFRSIGDPVSRLDRLEPGLNSAPAGDPRDTTTPAAMAATMETLLLGTGLTPASRA -QLTEWMRHGGVTGALLRKSAPADWQIADKSGAGDN-SRNLVALITPPGRAPWIAAIYLGD -AETDFATRNKALAEIGAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A3C0X538_9GAMM -------DFAALEKASGGRLGVTVLDTGSGRRHgGHRQDERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLLPPSRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEAQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C99BA5A ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI00001125EC ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0009822EB5 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESHVDAGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A106Q6G5_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLIGSANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. 115 TaxID=1162282 RepID=I4VJN5_9GAMM ---AIAGELATLERQHGGRLGVAMLDIGSGRHA-GHRAGERFLLCSTGKLLVVGAVLARVD -RGEEQLSRRIVFGPDVILEWAPVTRKHVGAPMTVAELCHAALTISDNTAMNLLLKGMGGP -VAATRFVRSLGDDITRLDRHESELN--VPDKDLDTTTPEAMLASMRKLLLGNVLSASSRA -QLIDWLRHNTTGETQLRAGMPANWQVGDKTGSGHT-QTNDVAIAWPPGRQPLLVTAYYEG -PADQGDMRKAVLAHVGKLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 06738 TaxID=2203210 RepID=A0A3Q8UWV4_9ACTN --qRATREFKELERAHDARLGVYAVDTRTGREV-AYRAGERFAFASTVKAFEAGAVLRQRK ---LAGLEKEITYDRSDLVANSPITEKHVDDGMTLGELCDAAVRYSDNAAANLLFEEIGGP -KALQSFLRETGDDTSRMERIEPALSDWEPDAVRDTSTPRALAGNLRAFVLGDVLDTPERA -RLAEWLRTNTTGDETIRAGVPKDWEVGDKTGTAAFGGRNDIAVVWRPDAAPLVMAVLSHG -TDRDAEPDDELIAKAAAVVSD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium obuense TaxID=1807 RepID=A0A0M2JWH4_9MYCO ------DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDMLAMCSTFKAYASAAVLQRAQ -QGRLALTDAVLVGRSDIREHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP -SAITDFARSIGDDRTRLDRWETELNTAIPGDPRDTSTPRALGSGFRAVLTGDVLDGAHRQ -MLEDWMRANQT--SSMRAGLPGGWATADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS -ATPDADSLRPLIGEIAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Vibrio TaxID=2614977 RepID=UPI000C8248FB ------ESIEQIESRVSGRIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLDLESKVGVNSDELIAWSPVTKAFVGKEISLRGACAATMAMSDNTAANIVLASIGGP -NGLTEFLRSTGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNKLLYGSALSEESKA -QLKTWMIDNKVSDGMIRSILPDGWKVADRSGAGAYGSRAITAIVWSENRAPLIISISLTE -TELTIPERDTVINEIGELIFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007576F52 ---AAQAQLDALEQASNGRLGVAALDTASGARI-SHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANSVAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Labrenzia sp. CE80 TaxID=1788986 RepID=UPI00129B1204 ------QQAIEIEKRHDARIGIAVLDDKTGTAW-SYKGDIRFPLNSTFKAFACAALLAQVD -DGTTDPNKSVQIKRADIAPYSPVTKKQIGKTMSYLGLCNAAVTISDNTAANYILKEIGGP -AGLSAFLRKLGDTETRLDRWEPELNNVPAGELRDTTTPIAAATTLKTLLLGGPLSANSRK -QLTDWLVANKVGDTLLRAGLPQRWKIGDKTGADAKKSRGDIAVIWPRPDRAVFVAVYLDE -AHVDMSRRNAAIAEIGRALTK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0003616D4E ----TTARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVIHYTEADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAGNLLLRELGGP -QAVTRFARSLGDRVTRLDRWEPVLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] Beta-lactamase n=1 Tax=Psychromicrobium lacuslunae TaxID=1618207 RepID=A0A0D4C4C1_9MICC ---------------------------------------------ATFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=A0A2N3SDD6_9ACTN --------LIRLEREFDARLGVYALATGTGNVV-AHRADERFAFCSTFKGLAAAAVLARNP ---LSHLDTVVRYDRSDLTANAVVTSRHVDRGMTIRQLCDAAVRHSDGTAGNLLVRDLGGP -AQLTAYARSLGDTVTRMDRIEPAITQATPGDPRDTTSPRAIGTDYQKILLGDALVPEKRA -FLRDLLERNATGARRIRAGVPKGWTVADKTGTGGYGTVNDIGVVWPPGASPLVIAIMSSK -ASRNADHDQAIIAKATEYAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075834EB ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGALERA -QLTKWLLGTANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus anmyonensis TaxID=405782 RepID=UPI0005AA6C13 ----LHGRLRALEQEHSARLGVFAYEPGTGRAV-LYRADELFAVCSTWKTIGVAAVLRDLD -RDGEFLAHVVHYTQQDATAYAPITGDNVAHGMTVADLCAAAVDYSDNGAANLLLRQLGGP -QAVTRFCRSVGDRVTRLDRWEPALNSAEPGRVTDTSTPRALGLTYARLVLGDALDPADRE -RLTGWLLANTTSGQRFRAGLPKDWTVADKTGTGQYGTTNDVGIAWPLRRGPVVMSVLSTK -RDAAAAADEPLIAQAAQLLATAf ->[subseq from] Beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=A0A0K6HP48_9BURK ---TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI00051821CD -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLSRVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB01249 TaxID=1703929 RepID=A0A1Q5DX63_9ACTN ----TTARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVIHYTEADCVSDSPVTDTHIASGLSVARLCDAAIGDSDNTAGNLLLRELGGP -QAVTRFARSLGDRVTRLDRWEPVLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharopolyspora sp. ASAGF58 TaxID=2719023 RepID=UPI00143FCA02 ------PAFADLERRYDARLGLFAVNVHTGQFL-GHRAGERFAMCSTFKTYAAAALLREHG -LDSGYFDKMIHYTEADLVDGSPITKPNAGTGMMVHELCAAAITRSDNTAANLLLAELGGP -ATIAPFARSIGDGSTRLDRWEPDLNMAIPGDERDTTTPAGIAAGYRALVVGDALRGPEHD -RLTGWLFANTTGGKRIRAGLPPTWRTGDKTGTGDYASGNDVAVTWTDKGHPIVIAVLTSR -PRKGDEVNNGLHVDTARVVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. BK438 TaxID=2512151 RepID=A0A4V2SST3_9ACTN ----TTARLRELERAHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVVHYTEADCVSDSPVTDTHLVSGLSVARLCDAAIGDSDNTAANLLLRELGGP -AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRK -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDVAEALA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI00021A91E7 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGTRSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDVIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax xenomutans TaxID=1094342 RepID=UPI000BD71558 ---ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP -GALTEFLRESGDPVTRLDRLEPELNGYGGADESDTTSPGAMLDTLYRLLFGEVLSAHGRA -QLAAWMIVNKTGDRRLRAGFPANWLVADKTGTSGLGYSNDIGVAWSPARGAVLVTVYCEM -PKAEAEARDRIIAEVAEMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteriaceae TaxID=1762 RepID=UPI0007A0FBEA -------ELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Aurantimonas coralicida TaxID=182270 RepID=UPI0004A269E6 ---RLAETVRGLEERLDARIGVFIRDSGSDWQW-GHREDERFLMASTFKSVLCGAVLEQAE -QGALALDEPVEIRAADILSYAPVTETRQGGTMTIGELCLATTDMSDNTAANLLLARLGGP -QAVTAFLRGIGDGVTRLDRTEPDLNIFAPGDPRDTTSPKAMATSWESMLVGDGLRPDSRQ -QLREWMRLGGVTGKLIRASTPRDWEVVDKSGGGRTHTRNLVAMITPPGRAPVFVAIYLSD -SPADFSTRNAAVAEIGAAIV--- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. AG1104 TaxID=2183900 RepID=A0A370EY75_9BURK ---TLSDELAALEIQSQGRFGLHVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALAGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWKVGGKTGSGERGTACDTLIVWPTEQAPLLVTAYLTG -SQLDGAGREAVLARAGEAVKR-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=A0A3N1DT91_9ACTN -----SRSLAALERTHGARLGVFAWNTVSDRIV-RHRGDELFPACSVSKTPAVAAVLRDLD -RDGEFLRKVIRYGADDVDRYAPVTGENLANGMSVSDLCAVAITHSDNTAMNLILEELGGP -TAVTRFCRSIGDTVTRLDRWEPELNSAEPGRVTDTTSPLAMGKTYARLVLTGTLGTADRD -RLKGWLLANTTGDNRLKAGLPASWTVAEKTGTGDYGTTNDVGVAWTDKGEPVVLAVLSTK -ADAEAAADEPLLAEAAWVIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. NRF60-BP8 TaxID=1637853 RepID=UPI00075D92FC ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKSAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNQATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGNGGFGTTTDVAVLWPPSRAPIVMAVSFTQ -PEAAAAARADVVAAAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcanivorax TaxID=59753 RepID=UPI00047DDBC9 ---ALGHRCQEWERRHGGRIGVAVWNLATGYRA-GHRVDERFLMCSTFKALAAALVLARVD -QGQESLDRRLLVSRKDLVGWSPVTEKRTGEGMTVAELCEAAVAWSDNGAANLLVKGFGGP -GALTEFLRESGDPVTRLDRLEPELNGYGGADESDTTSPGAMLDTLYRLLFGEVLSAHGRA -QLAAWMIVNKTGDRRLRAGFPANWLVADKTGTSGLGYSNDVGVAWSPARGAVLVTVYCEM -PKAEAEARDRIIAEVAEMV---- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X4S6_9BACT ---SARKQLNKLEHSLDGKIGIFAMNTANQQTI-HYRSKERFPIQSTFKLMVVAAILKKSA -TDPELLQKKIFYTKNDLVTWSPITEKRIDSGMSILELCDATMKYSDNTATNLLMKQVGGP -AVITDFAHSLGDSVFNVLHYEAELNSN-PNSTDDTSTPENMGINLKKIAFNPILPSSYIH -LLLNWMKENTTGDAQIRAGVPKEWVVADKTGSSSFGTSNDIGIIWPTGCDPIIIAIYTVQ -NKEDATKRNDILKDATRTVINEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXP4_9BACT ---SARKQLNKLEHSLDGKIGIFAMNTANQQTI-HYRSKERFPIQSTFKLMVVAAILKKSA -TDPELLQKKIFYTKNDLVTWSPITEKRIDSGMSILELCDATMKYSDNTATNLLMKQVGGP -AVITDFAHSLGDSVFNVLHYEAELNSN-PNSTDDTSTPENMGINLKKIAFNPILPSSYIH -LLLNWMKENTTGDAQIRAGVPKEWVVADKTGSSSFGTSNDIGIIWPTGCDPIIIAIYTVQ -NKEDATKRNDILKDATRTVINEf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. AND4 TaxID=314289 RepID=A8T2U3_9VIBR ---KLNEAISAIEEHISGRIGVSVWDTQTDERW-DYRGDERFPMMSTFKTLACATMLSNMD -NETLDKNATAKVEKHNMVVWSPVMDRMAGQTIRIEHACEAAMLMSDNTAANIVLRSIDGP -QGVTKFLRSIGDKITRLDRFEPTLNEANPGDKQDTTTPNAMVNTLNTLLESDALSYESRI -QLKIWMQDNKVSDSLIRSVLPKGWSIADRSGAGGFGSRGITAMVWKENHRPIYISIYITE -TDLSLQARDQVIAQISQLILDGy ->[subseq from] Beta-lactamase n=1 Tax=Leifsonia aquatica ATCC 14665 TaxID=1358026 RepID=U2RTW4_LEIAQ ---STQRAFAELERTHGATLGVTAIDTGNGRTV-AYRGGERFPFASSNKTFIAAALLGRSS ---DADLDQVVHYTSADLLDYAPITSRFVDTGMTVRELIDAMLRFSDNTAANLLVARLGGP -DAVEQWLRGIGDRTTNVDRVEPDLNEALPGDARDTTTPAQFASDLRAVLLGSALETKDRT -LLRNTMLDNTTGDDTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPVGRAPIVVVTLSRK -ATPDATPDNALLAAATKTAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI00036EE5D4 ------NELASLEKDFVGRIGVYALDTGSGDTV-SHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-146 TaxID=1463884 RepID=UPI00069016F0 -------RLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS ---AGGLDRRVTYTEADLCSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -AGLTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRELLLGTALPVRERR -LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTGPLVLAVMTDR -PGHDAEPSDALIAEATRRTV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000758AB0D ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANGVKGIRASVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFSQ -PGADAAPRADVVTEAARIAA--- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=UPI0006803E4B ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEGDALSYEARI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG -TDLSLQARDQVIAQISQLVLDEy ->[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium HGW-Actinobacteria-11 TaxID=2013646 RepID=A0A2N3GUI9_9ACTN --------LQELEWRFDARIGVHAIDTGTGRSI-AHRDDERFAFCSTYKAIAAAEILRSRA ---ISGLEKRVRFTADDLVSYSPVTEQRVASGMSLRELCVAAVRFSDNTAGNLLFRELGGP -QGMASALREIGDDVTVMERIEPELNTAIPSETRDTSTPRMLVRDLQAYATTDLLPIEKRS -ILRGWMSGNATGDALIRAGLPDGWTVADKSGAGAYATRNDIGIVFPPGKSPIVIAVLTSK -LRQDATYDNEVIAEATRLVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A69DAD ------NELTSLEKDFGGRIGVYALDTGSGDTV-GHRADERFLMCSTVKTFIVSAILHRRQ -SEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSDNTGANLLIAQLGDP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIALRAf ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas niordiana TaxID=2508711 RepID=UPI0010A07D4A ---DLDQRLAELERATDDRVGVALMNVTTGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -EGSETLDRRIVVEKGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIDSVGGP -KAVTAFLRAIGDDTTRLDRVEPDLNTDHEGDERDTTTPLAMMATLRTLLLGDALTPSSRH -QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIGWPGDRGAVIAVAYTKM -PGATGQQRDEAIATVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI000F013920 ---DVQSRFAELEHKYAARLGVYVPASGATAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDKVVTYTSADIRSTSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT -TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPNAIALDYQQLVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000981EF9D ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVTSAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB94_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ATCM1_4 TaxID=2259330 RepID=A0A4R4IGY7_9GAMM ------DDFAALEALSGGRLGVCLWNPDSGVRI-GHRMEERFPMCSTFKFLLSAAVLHAAD -QGQLSLDRRVPVRAHDILSNSPGTERHVGKDMTVRDLCRTTMIVSDNAAANLLLPLVGEP -AGLTAFLRAQGDAVTVTARYEPEANRFAPDDPRDTTSPAAMAGNLQRFVLGDALGTAARQ -QLADWLIDNETGDARLRAGLPEGWRVGDKTGSNGRDTTNDIAVLWPAGGSPWILASYLQG -SALDDDGRNGILRRVGELA---- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_001 TaxID=1898731 RepID=A0A1S2GX72_9MICO ----TDRAFRALEAQHDARLGVVAIDTGSGHRV-QYRPGERFPFASTNKTFIAAAVLAASS ---DADLDTVVHYGRGDLLSYAPVTTRFVDSGMTVGELIDAAMRFSDNTAANLLVARVGGP -AAVEQWLRGTGDRVTNVDRTEPDLNQATPGDERDTTTPAQFAADVRSVLLGTTLEATDRT -FLRDTMLDNTTGAGTIRAGVDAAWPVADKTGTGEYGVRNDIGVVYPAGGAPIVVVVMTAT -DRADAQADDALVAAASGTAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. ABCPW 11 TaxID=1637859 RepID=A0A103BEU2_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PEAAAAARADVVAAAARIA---- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea violacea TaxID=128104 RepID=A0A1G9TRR5_9PSEU ------DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTRYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD -FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGQYGTVNDIAVVWPPGREPVLIAIMSSK -STADAKYDEALVAEAAAYVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000A06A233 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -LQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. WAC08241 TaxID=2487421 RepID=A0A429PAD5_9ACTN ----HRREFRALEEAFDARLGVYAIDTGTGREI-THRDGERFPYASTFKALAAGAVLRE-- -EGLGGMERVVRYTKDELVDPSPVTEKHVDTGMTLDALADAAVRYSDNTAGNLLFEELGGP -KGLQAVLRSIGDGVTRMDRIEPGLGDWRPGEVRDTSSPRALAGDLRAFVLGDVLRAPERK -RLTTWLRTSLTGDGTIRAGVPGTWVVGDKTGTATYGGRNDMAVVWPPDGAPIVMAILSTR -SDREAEPDDRLVARAASVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium senegalense TaxID=1796 RepID=A0A378T2U5_9MYCO ----IDDQLAELERRDNVLIGLYASNLDSGRTL-THRADQIFAMCSTFKGYAAARVLQLAE -RGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPSQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A172WXH6_PSEST ---ALTETVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD -RDEVELDTRVRFDETDLQSYSPITKDRVGGSMSLFELCSATTSMSDNTAANLILRNTGGP -QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE -QLKAWLVNNKVGGPLLRASLPEGWKIADRTGAGGYGSRGIIAVIWPQGSEPVIVAVYLTG -TTLTLEERDATIAEVGAALV--- ->[subseq from] Beta-lactamase n=1 Tax=Neisseriales bacterium TaxID=2053582 RepID=A0A5C8B084_9NEIS ------QQMSKLESTVGGRIGIAVYNTRNKETL-SYRGNERFPFCSTGKVMTVAAILKASE -KESDLLTKIIKYTKTDTDKYAPITSKYLAKGMTISELSQAALDYSDNTAMNLLVAEAGGV -GKITDYARLIGDEKFRLDRMEPELNTSIPADKRDTTTPLAMTMSLDKLVLGQSLESNSQI -YLTKWLKANTTGDKRIRAGLPQGWIVGDKTGTGAYGTTNDIGVIWAAKCDPIVISIYYTQ -DQKAAKSNDSVIASATKVAID-- ->[subseq from] Beta-lactamase (Fragment) n=7 Tax=Xanthomonadaceae TaxID=32033 RepID=D2CGR5_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000668AB8D ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMIGGARGATGIAAGAPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9140 TaxID=2184572 RepID=UPI000F568F7D ---AAQAELAALETASDGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVAAAAAILARGS -LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP -QAVTSFAHESGDSAFRLDRWEPELNQVAPGDVRDTSTPVAMVDLLQRLLLGDTLREPQRA -QLTEWMTGGARGAAGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAVRADVVASAARIATGAf ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. SAU14A_NAIMI4_8 TaxID=2072409 RepID=UPI000D53C5E7 -------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQHERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDTVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLLPPSRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEAQRAAVLARVGAL----- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. Ru87 TaxID=2044307 RepID=A0A2B8B2X1_9ACTN ---EVTRRLRALEREHSARLGVYARNLATGATV-LHRTDERFPVCSLFKTLAAAAVLRDLD -RSGEFLAKVVHYTEDELDKWSPVTGENLEHGMTVDELCHAAITRSDNSAGNFLLRELGGP -GAITRFCRSIGDDRTRLDRWEPELNSAEPWQWKDTTSPGAIGRTYARLVVGDVLEPHDRE -RLTGWLLANTTSGEQFRKGLPADWTVADKTGAGGYGTTNNAGVAWTPDGAPVALAVLTTK -FHQDAGNDRALVAGTAELL---- ->[subseq from] Beta-lactamase CARB-3 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=BLC3_PSEAI --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKLLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase class A n=1 Tax=Thermostaphylospora chromogena TaxID=35622 RepID=A0A1H0ZYX1_9ACTN --nRVTKELRELEASFKGRIGAYAVDTATGKTI-GYRAGERFPLLSTFKTFLCAAALHKAR -TTPGLMEKRIRWTENDLVDHSPVTEKHLKNGLTVAELCKATITTSDNTAANLVLKEIGGP -AGLTRYFRSLKDPISRLDRYETELNNWSLHDRRDTTTPRAIGRDMRAVTVGKALHPKDRE -RLNAWLIANETGDHRIRAGLPKSWKIGDKTGTVPHGSGNDIAIIWPGKSAPIIMAIYTYR -KAEDAPVAEEVIAKTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium vignae TaxID=1549949 RepID=A0A4Q0R9B1_9BRAD -------ELETYERESGGRVGLYAENLVNGKKL-AWRADERFVMCSTFKASLAACVLGRVD -RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTGFWRSLGDTTSRLDHDEPELNRSPPGNPQDTTTPAAMANNLRRLVLGEALSAQSRV -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGYNGKDAAGDIAVAWPKPDTPVLITAYVQG -GTPTPAKIAGVFAQIGRMVTD-- ->[subseq from] class A beta-lactamase n=2 Tax=Citrobacter koseri TaxID=545 RepID=UPI0009B9008E ----------QEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKVLALSASTQFESSQLVEYSPITEKHVVPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADSLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24572 TaxID=1962156 RepID=UPI000A37832E ------ARLRRLEREHTARLGVFARDMRTGRTV-AYRADERFPMASLFKTLAAAAVLRDLD -RDGEFLARRIHYTQAYVERLSLIAAENVAGGMTVAELCDATIRFSDNTAGNLLLKELGGP -TAVTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPRAIGLSYARLVLGDTLEPHDRA -RLTDWLLRNTTSTEKFRRGLPADWALADKTGSPRHGGANDVGVTWRPDGTPIVLSVLTTQ -PEEDAPTDNPLVAATAALLAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. Tr-654 TaxID=2608341 RepID=UPI0014204DF5 --kTLSDELAALEIQSQGRLGLHVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLSQ -RDEIRLWRKLYYSPAEVVAWSPISEKWAGANMTVQELCEAMVVVSDNTAANVMLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVHSLQKLLLGDVLEGYARA -LLQQWLADSRTGDKRVRAGMPSDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLAKAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 141 TaxID=1120797 RepID=UPI0003699358 ----LDDQIAGLEQRNNALIGIFAANVDSNRTV-AHRADETFAMCSTFKGYAVGRVLQQVD -RGQLALDTRIFIDPSAIVANSPVTEERAGADMTIGELCQAALQHSDNTAGNLLLKMIDGP -PGVTAFARSIGDDRTRLDRWETALNSAIPGDLRDTSTPAALGAGYRALLTADVLSRPQRQ -QLEDWMRGNET--SSLRAGLPAGWTSADKTGSGDYGSTNDVGVAYGPDGQRLLLAVMTRS -RADDPEAAN-------------- ->[subseq from] Beta-lactamase n=2 Tax=Comamonas testosteroni TaxID=285 RepID=A0A1Y1J6V8_COMTE --kTLSDELAALEIEAQGRLGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWKAGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SQLDGAGREAVLARAGEAIK--- ->[subseq from] Class A beta-lactamase n=5 Tax=Mycobacteroides TaxID=670516 RepID=A0A0R3EKR5_9MYCO ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A249VY78_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATAKIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNSAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILEHy ->[subseq from] Beta-lactamase n=1 Tax=Agromyces sp. NDB4Y10 TaxID=1775951 RepID=A0A164CTG2_9MICO ----ASDELSALEQEYGARVGVYAIDTGSGDVV-AYRGDERFAYASTIKALLAAAILQQVD -----DLDRVVPYSADVLGSHSPVTSGAVGGGLSVRDLAEAAVRVSDNTAANLLLDQLGGP -EGFAAVLAEAGDATTNPVRVETELNTAVPGDTRDTSTPRALVESLRGFALGGLLTDARSD -TLIEWMSGNATGDTLIRAGAPDAAIVADKSGTGGHGTRNDLGIVWPVDGEPIVIAVLTTR -GVPDAPSDDALVADAAAAVLSAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075C5072 ---AAQAQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLIGSANSIAGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADASPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora mongoliensis TaxID=688067 RepID=UPI0008344D6F -----VADLRALETSYHGRIGVYAIDTATGRTI-AYRSGERFPLASTFKGVLAAAVLDKKP ----DILGKRILIKKKDLLPNSPETEKHVGSRMTVAALARAAVTKSDNAAANLLLKQVGGP -KGLTRYFRGLNDHVSRLDRTEPGLNDWTPKDPRDTTTPAAIARDLKALTVGTALDAGDRR -IFTGWLVANETGDKRIRAGLPKSWRIGDKTGTGSYGSANDYAIIWPKGSKPIIMAIYTNR -TAKNGTADETVIAKAATIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000634A596 --sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNSMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus saharensis TaxID=1137994 RepID=UPI000B77840F ---AVAARLAALEEEYGARLGVHAVDTGSGRTI-AHRADERFAYASTVKALAAGALLARTS ---PVDLQRGVPISRADLAPHSPVTEAAVGGSLTLEQLCDAAVRFSDNTALNLLLRELGGP -AGLDAALERVGDDVTEVSRTEPALNTAVPGDPRDTTTPRALATTLRAYAVGAGVAVEDRL -LLADWLRRNTTGDTLVRAGVPGDWEVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR -GERDAGHDDALIAAAAGVVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas abyssi TaxID=170540 RepID=A0A2A3MFJ5_9PSED ---ALNLALAELERASQGRLGVSLLDRGSGQVA-SYRGDERFLMLSSFKTLAAAYVLARSD -QGIDQLSRRISITEEDMLEYAPVTRRHIGPRMTLAELCHATITTSDNTAANLILRSYGGP -QALTQFIRSLGDTITRHDRYEPELNQSHSVEPMDTTSPNAMSNTLNTLLLGSALKPESRQ -LLQSWLMANTTGDRRLRAGVPPSWIVGEKTGTAGL-GANDVGFIQAPSGSPVIVSVYLET -DTIAAPERDQIIAAVGKRAA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000DE296C1 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTMACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=4 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2A3I9A5_9ACTN ----LAAQLRDLEQQYSARLGVFARDTATGRTV-KYRADERFPMCSVFKTLAAAAVLRDRD ---DDFLGHRIRYAEKYVTDYAPITGKNLANGMTVGELCAAAVSYSDNGAGNLLLGELGGP -AAVTGFCRSIGDGTTRLDRWEPDLNSAEPWRKTDITSPRAIGQTYARLVLGSTLTTADRT -RLTRWLVANTTNGERFRAGLPADWTLADKTGGGQYGVANDVGIVWPPGRPPLVLSVLSTK -FDPEGPTDNPLVAKAAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML130969 TaxID=2480811 RepID=A0A4Q8M3X8_9GAMM ------RDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAD -AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP -PALTAFLRKQGDAVTRSDRYEPEMNNFAPDDARDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG -ARVDADQRDAVLARVGALA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides abscessus subsp. bolletii 50594 TaxID=1303024 RepID=R4UF27_9MYCO ------NELASLEKDFGGRIGVYALDTGSGDTV-GHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSRGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDSAPIVMAVLTVP -EDPTFTKGKPTIAAAARIVLRAf ->[subseq from] Carbapenem-hydrolyzing beta-lactamase FRI-4 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=A0A1S7IV31_ENTAS ------EQMRELETSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ -DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAISLNNIAFGSVLDAKNKS -LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR -PNQNDKHDETVIKNAAKIAIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007520D9E ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNMARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVKGIRAGVPSDWRVAGKTGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAVPRADVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F57B555 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVTSAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. C1-2 TaxID=2720022 RepID=UPI00143275DA ----LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD -RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP -SGITRFCRSLGDDTTRLDRWEPDLNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE -RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVANDVGVVWPPARPPLVLAILSTK -LDPAGPTENPLVAKAAAAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces jietaisiensis TaxID=235987 RepID=A0A1G7DB66_9ACTN ----LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD -RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP -SGITRFCRSLGDDTTRLDRWEPDLNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE -RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVANDVGVVWPPARPPLVLAILSTK -LDPAGPTENPLVAKAAAAVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2ZC81_9ACTN ---DLTRELRALEKRYDTRLGVYARNVGTGQAV-RYRGDERFPMCSTFKGLLAAHMMRDYD -RRGEFLERVLHYTRDDLAGWSPITENNLETGMAVRDLCLAATAFSDNGAANVLLRATDGP -PGFTRFCRAIGDEYTRLDRYETDMSEAKPGDDRDTTTPEAMGRSYARLVLGRVLKPFHRD -QLVSWLKVNTTSGPRFRAGLPDDWVLADKTGNGGYGTVNDIGIVWTPKGTTLLLSVLSTK -EMKGVEADPRVLADTARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI000D8C5185 ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLVEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLAKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAVKNDPRDTTTPNAINHTLNTLVLGETLSSASRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSTQQEPMFVSIYLTQ -TEASFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=2 Tax=Comamonas TaxID=283 RepID=A0A0M2DLK3_9BURK ---TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SSLDGTGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora yilanensis TaxID=354426 RepID=UPI0007862FDC -----VAELRALETSFKGRIGVYALDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKKP ----DILGKRILVRKKDLLPNSPETRKHVGSRMTVAELAKAAVTKSDNAAANLLLRQVGGP -KGLTRYFRSLDDHVSRLDRDEPGLNRWHPGELRDTTTPAAIAADLKVLTVGGALDAGDRR -TFTGWLVANETGDDRIRAGLPKSWRIGDKTGTGGYGTANDYAIIWPKGSKPIIMAIYTNR -TDRNAAADESVIAKTATIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. NFR13 TaxID=1566285 RepID=A0A1I4M8N4_9BRAD ---ALHAPLQAYERDTGGRIGVYAENLKTGTKI-AWRAHERFVMCSTFKASLAACVLARID -RGEDKPDQMIPYAAADLLQYAPVARDNLARGLSVADMCKATVELSDNTCANMLLARVGGP -AALTAFWNKTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFITGNVLTPASRD -QLIDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG -GTPTAPQLETVFTAIGEMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID9124 TaxID=2706108 RepID=UPI0013E002DB ----ATARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLGKVIHYTKADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAANLLLRELGGP -AAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNVLERRDRE -RLTYWLLNCRTSGTRFRAGLPPEWAVADKTGGGSYGSCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAEALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AU31280 TaxID=2015353 RepID=UPI000B7AC80C ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAMLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia diffusa TaxID=488732 RepID=UPI000758BECD ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHESGDTVFRLDRWEPELNQAAPRDERDTSTPVAMVDTLQRLLLGDTLREPERA -QLTEWMTGGARSATGIAAGVPPGWRIADKIGSGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces europaeiscabiei TaxID=146819 RepID=UPI0006284352 ----LSRQLGELEREHAARLGVFAHDTATGRTL-AYRADERFPICSVFKTLGAGAVLRDLD -RDGEYLAKRIHYTKEYVEAYCPITARNVAAGMTVGELCSASVSHSDNGAANLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPQLNSAEPWRKTDTTTPRAIGGTYARLLLGRALPDADRE -LLTDWLIANTTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPLRPPLVLSVLTTK -HAPEGPSDNPLVAKAAGLVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3NZE4_MYCAS ---DLSHQFDQLERRYEGRLGVYVPE----PAI-AYRADERFAFCSTFKAPLAAAVLHQYP ---LDHLDKLVSYNRSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDGTAANLLLAEVGGP -AGFTAYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGDALPADERV -LLVDWMTRNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF -VGYDAQPNDAFVADAARIVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. BE17 TaxID=2656644 RepID=UPI00128D295F ---AAQAELAALEKASNGRLGIAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLRSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDRWEPELNKAAPDDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Jiangella sp. KE2-3 TaxID=1623398 RepID=UPI000E357074 -------AVRELERTHDVVLGVSATNLATGAQL-AHRAGDRFPILSVFKSVVAAAVLRDLD ---DARLDHRVWYPPADILLNSAITAEHVDTGMTVAELCDAAIRYSDNAAGNLLLREVGGP -RGLTAFARSLGDRATRLDRWEIELNSAEPGDVRDTSTPAALARTFAGLLVGDLLRPADRR -RLRNWMLANTTSGPRFRDALPDGWLLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR -TERDAERVDAALADVARLVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Root264 TaxID=1736503 RepID=A0A0Q9ACN2_9ACTN ---ALSRRLRDLERRYSARLGVFALDTATGRTA-EYRADERFPLCSVFKTLAAAAVLRDLD -HDGAYLARRIHYTEKDVTDYAPVTGENIAGGLTVEELCAAAVSESDNGAANLVLRELGGP -TAITRFCRSLGDRTTRLDRYEPALNSAEPWRRTDTTRPRAIGLTYARLVLGRALESADRR -RLTGWLIANTTNTERFRAGLPDDWTLADKTGGGQYGVANDVGVVWPPGRPALVLAVLSTK -HDPAGPTDNPLVAKAAALTA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf87 TaxID=1736243 RepID=UPI000700F869 ----ATNTLREIERRVGGRLGVSVGKSNAPPLL-GHRADERFPMCSTFKVPAAAALMARVD -AGTESLDRALPYGEEDLLKYAPVTRKALEAAISVADACAAAVEWSDNTAANLMLNVLGGP -LALTGWLRGIGDPTTRLDRTEPDLNTAIPDDPRDTTTPDAMRTTLEQILVGTALSRATRT -RLDGWLAAGRTGSKRLRAGIPPDWKVGDKTGSGDNGTYNDVAILRPPWQAPILAAVYLTG -STAPITDVDAAYAEIGRMIAE-- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase FRI-9 n=1 Tax=Enterobacter asburiae TaxID=61645 RepID=UPI0010CA2EDA ------EQMKELENSFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKRTQ -DKSVSLDDMMEYSGRVMEKHSPVSEKYRETGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKTVAMSLNNIAFGSVLDAKNKS -LLQDWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDIAILWPDANSPAVMAVYTTR -PNQNDKHDETVIKNAAKIAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ACS4331 TaxID=1834121 RepID=A0A1A1X9C1_9MYCO -----DAALAALEQRYDALVGLFALDLDSGRSL-AFRDDDPFAMCSTFKTYAAGSVLQRDQ -RGELQLDRQVFVDPAELVANSPVTEVNAGSSMTLAALCQAALQRSDNTAANLLLQTIGGP -PAITAFARSIGDDRSRLDRWETELNSALPGDPRDTSSPRALAGGYRALLTGTVLDEPHRA -QLETWMRGNATSEKSLRAGLPPGWTSADKTGAGDYGSTNAVGIAFAPDGRRLLLSVMTRS -RSPDAPWLQPLIAEVTALAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. F12 TaxID=2070776 RepID=A0A4U1X2L0_9VIBR ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLDLESKVGVNSDELIAWSPVTKAFVGKEISLRGACAATMAMSDNTAANIVLASIGGP -NGLTEFLRSTGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNKLLYGSALSEESKA -QLKTWMIDNKVSDGMIRSILPDGWKVADRSGAGAYGSRAITAIVWSENRAPLIISISLTE -TELTIPERDTVINEIGELIFDEy ->[subseq from] Beta-lactamase n=1 Tax=Labedella endophytica TaxID=1523160 RepID=A0A3S0WZC7_9MICO ---ATDAAFSALESEFDARLGVYALDTGTGEEV-VWRADERFAFASTYKALAAGAVLDQVG ---IEGLDTSVMYGGKALVEYSPITEKYADIGMTIGDLADAALRYSDNTAGNMLFEVLGGP -TGFDTALEALGDDVTESVREETELNAAERDETLDTSTPTALATDLRAYLLGDVLSDDERA -VLTDWMVRNTTGDTLVRAGVPDDWTVADKSGSAKYGTRNDIAVVWPTDGDPIVLAILSDR -DTEDAERDDALIARATEEAV--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A377ZRY4_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGER-V----------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. BTF04 TaxID=2708300 RepID=UPI0013D3EFD2 --eAARRRVAAIEHELGGRIGVAVLD-GSGPVL-LHGADDPFPLCSTFKLLATAAILKRVD -DGTLRLDQEIAYDAADLTAYAPITAAALRDGMSLESLCAAAMVWSDNTAANLMLRTLGGP -AALTAYLRGLGDPTTRLDRTEPTLNTAIPGDPRDTTTPAAMAKTTRILLTGAALRADSRN -RLESWMVAARTGTKRLRAGLPPDWIVGDKTGSGDNGTANVVAILRPPARPPLVAAIYMTG -STQPPETRDAAHAEIGRILA--- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. SCN 70-31 TaxID=1660129 RepID=A0A1E4GVL5_9CAUL ------PAWASLEARVGGRLGVFGVNSGNGRTF-GWRADERFPMCSTFKGLLAGAVLARVD -ARRERLDREVQLSPADMVAHAPVTSRYLAAGVRVETLCQAIVEVSDNPGANLLLKTLGGP -RGFTRHIRAQGDRATRLDRYETELNSAIPGDPRDTTTPAAMVGSYRRLLLGPALTLASRR -RLAGWMEAASTGLTRLRADLPAGWRAGDKTGSGAHHTANDVAILWPPAGAPILVGCFSTQ -ATAP-EARDAVMAGIGRLAAE-- ->[subseq from] Beta-lactamase PSE-4 n=3 Tax=Pseudomonas aeruginosa TaxID=287 RepID=BLP4_PSEAI --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMEERNDAIVKIGHSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kubicae TaxID=120959 RepID=UPI00080012E9 -----SDRIDELESQYHAFAGVYAQDLDSGHTV-THRADDPFAMCSTFKAYAAGRVLQKAQ -RGELDLDQATFIDPNELQPNSPVTAPHAGHSMPLAQLCAAALQRSDNTAANVLLQAIGGP -PAITEFARSIGDDRTRLDRWEVELNTAIPHDPRDTSTPRALGAGIQNLLAGTVLAPPQRR -QLETWMRGNVT--STMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPNGQRVLLAIMTRS -QAPDADALQPLIADVTRAVL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A431I7S4_9PROT -hdDLMAQLRSLESTSATHIGVYAMNSANNQKL-EFNAEKRFPFCSTAKFITVAAILKNSE -SNPDYLQQQIKFTHYDVQTYSPITANHVTNGMTIAELSFAALAYSDNTAMNLLIASLGGI -TQVNNYARTLNDSRFRLDRPEPRLNTAIPHDLRDTTTPQAMGQDIQQLLLGNALNATSRD -KLAKWMIANTTGAKRIRAGVPQGWAVAEKTGSGDYGTANDIGVIYPNKCKPLVMSIYTTS -DKKEAKYQDEVVAKVTKLVLQ-- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-3 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A1S6GNZ2_ENTCL ------EQMRELEAAFGGRIGVYILNTKNGKEF-SYRQDERFPLCSSFKAFLAASVLKKTQ -DKSVSLDDMMEYSGRVMEKHSPVSEKYRKTGASVRTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNSAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS -LLQEWLKGNTTGNARIRAAVPDKWDVGDKTGTCGYGTANDVAILWPDANSPAVMAVYTTR -PNQNDKHDEAVIKNSAKIAIN-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis salina TaxID=245836 RepID=UPI0003458942 ---AAEEAFTDLESEYDARLGVYALDTGTGQEI-GYGADDRFAYASTFKALAVGALLHQHG ---AGVLDEEVPLGEDDLLTHAPVAEQLVEEGMTLREASDATVRHSDNTAGNLVLERLGGP -DGFEEALREIGDDTTSADRWEEELNEAAPGDERDTTTPRALAESLQTYVLEDTLAEDERE -FLTDLLVRNTTGDTLVRAGVPEDWEVGDKTGGGGYATRNDIAVAWPPEGDPVVIAVMSDR -EDEDAEYDDALVADATETVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=UPI000BE479C6 -------RLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS ---AGGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -AGLTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRDLLLGTALPVRERR -LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTGPLVLAVMTDR -PGRDAEPSDALIAEATRRTV--- ->[subseq from] Beta-lactamase n=1 Tax=Geodermatophilus saharensis TaxID=1137994 RepID=A0A239C0A2_9ACTN ---AVAARLAALEEEYGARLGVHAVDTGSGRTI-AHRADERFAYASTVKALAAGALLARTS ---PVDLQRGVPISRADLAPHSPVTEAAVGGSLTLEQLCDAAVRFSDNTALNLLLRELGGP -AGLDAALERVGDDVTEVSRTEPALNTAVPGDPRDTTTPRALATTLRAYAVGAGVAVEDRL -LLADWLRRNTTGDTLVRAGVPGDWEVGDKTGTGAYGTRNDVAVLTPPGRAPIVLAVMSSR -GERDAGHDDALIAAAAGVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007ED4B82 ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] Carbapenem-hydrolyzing class A beta-lactamase FRI-8 n=1 Tax=Enterobacter sp. 18A13 TaxID=2565914 RepID=A0A4P2WTJ5_9ENTR ------AQIKELETVFGGRIGVYLLNTENGKEF-SYRQNERFPLCSSFKVFLAASVLKKTQ -DKSFSLNDTVEYSGRVMEKHSPVSEKYLETGASVQTLAMAAIQYSDNGASNLLMERVGGP -EGLTAFMRSTGDTEFRLDRWELELNSAIPGDKRDTSTPKAVAMSLKNIAFGSVLDAKNKA -LLQDWLQGNTTGNARVRAAVPDKWVVGDKTGTCGYGTANDVAILWPDSNSPAVIAVYTTR -TNQNDKHDETIIKNAAKIAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Roseivivax isoporae LMG 25204 TaxID=1449351 RepID=X7FDK5_9RHOB ----LALTVRQIEDRLDARVGVVVRDSATGWSW-GHRADERFLMNSTFKAPLCGALLARVD -AGETTLDTALPVTAADMVDHAPVTETRIGATMTLDALCRAAVDMSDNPAANIVLDHVGGP -EGFTSFLRGIGDGTTRLDRTEPGLNTYAAGDPRDTTTPAAMVATLERLLLGDALSAAARA -RLTGWMTPGSVTGALLRAHTPEGWHVADKSGAGRV-TRNIVGMVTPPGAAPHLVAIYLSE -AEVDFATRNAALSELSAAVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonas serinivorans TaxID=1082851 RepID=A0A1Y0EPD6_9BURK ----LAADLQALERQANGRLGVQVVDTGTGREA-GYRADERFMMLSSHKLLAAGLVLYRHD -QRQDSLARRIRFTRADLVSHSPVTERHVGGQMTLAELCHATLTTSDNTAANLIHDSYGGP -QGLTRFLRGLGDDITRLDRRETALNVPQAGEPLDSTSPRAITRSMGKLVLGYVLTPASRR -QLQDWLVANTTGGRRLRAGLPTGWRVGDKTGTAEV-GANDIGVAWPPGRAPLLLSVYLEA -PP--TAARDEAIATAARLAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A0G3WYC3_BURPY ---AAQAELAALEKASNGRLGIAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLQSGDKGAGNLLMSVLGGP -QAVTSFAHGSGDTTFRLDRWEPELNQAAPGDERDTSTPVAMVDALQRLLLGDTLHEPQRT -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter porticola TaxID=1844006 RepID=A0A1L3I2V4_9RHOB ---DVTSVVHAWEAKLDARLGVLLRHPDTGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -QGTDQLSAPVKIRAGDLVAHSPVTERYIGGTRTVAQLCDAAITRSDNTAANLLMERVGGP -AGVTAYLRQTGDSVTRLDRWEAELNSATPGDLRDTTTPRAVLTSLQSALFGSTLTAQSAG -LLADWMERNHLADALIRAHLPRGWRIGDKTGGGGHGSRAIIAHLQDPKGETYLAAIYITE -TTAKFAQRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=2 Tax=Comamonas TaxID=283 RepID=A0A076PSC6_COMTE ---TLSDELAALEIQSQGRFGLYVVDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ -RSEIRLWRKLYYSPAEVVAWSPISEKRAGANMTVQELCEAMVVVSDNTAANVMLEASGGP -AALTQWLREMGDGTTRLDRNEPSLNTALPGDERDTTTPRAMVQSLQKLLLGDVLEGYARA -LLQQWLADSRTGDKRVRSGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharomonospora paurometabolica TaxID=208085 RepID=UPI00022E7C0F ------PDFAELERRYSARLGVYALDTGSGTEI-THRAGERWAFCSTIKPFTAMAVLQRTT ---LDGLDERITYSREDLVSYSPVTEQHVDTGMTLRAVLEAAVRKSDNTAQNLLLDELGGP -AGLQRALRELGDTVSHADRYEPELNDTAPDDIRDTSTPRALATNLRKLVLGDVLPPGKRT -ILREAMRNPPLTADLIQAGVPDDWQVEDKSGAGGYATRNDIAVLYPPERAPIVLVVLSDR -ARPDAEYDDALLAEAARVTV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID8455 TaxID=2706104 RepID=A0A6B3I9L6_9ACTN ----AVRRLAGLERASGARLGVYAYDSGSGRTV-AYRADELFPMCSVFKTLSSAAVLRDLD -RDGEFLSRRIFYTAKDVERGAPETGKNLANGMTVEELCEVSITASDNCAANLVLRELGGP -TAVTRFARSLGNRVTRLDRWEPELNSAEPGRVTDTTSPRAITGTYGRLVLGDALNPRDRR -LLTGWLLANTTSGGRFRAGLPKEWTLGDKTGAGRHGTNNDAGVTWPPGRSPIVLTVLTTQ -PEEDAVRDDGLVADAARVLAE-- ->[subseq from] Beta-lactamase n=5 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA2_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=A0A2P4UPW6_9ACTN ----VTGRIDALERSYAGRIGAFAVDTGNGRTV-AHRADERFAFASTFKAALAAAVLHKAR -SDPGLLHRRLHWTADDLLPNSPVTEKHITDGLTAAELCRAAITRSDNTAANVLLKQVGGP -AGVTRYLRSLGDSVSRLDHNEPALNQWKPGQRQDTVTPAAIGRDLASVTVGRALAAPDRA -QLNVWLRATVTGDARIRASVPGNWLVGDKTGTGSYGTANDIAVVTPPGHAPLIIAIYTNR -NDPKGDADESVIARTTTLLI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=A0A286CK13_9ACTN -------RLADLEREYGARVGVYALATGTGATV-VHRAGERFAFCSTFKALAAAAVLHHRS ---AGGLDRRVTYTEADLRSTAPVTGKHVATGMTLRELCDAAVRFSDGTAGNLLMRDIGGP -AGLTAYLRGLGDTTSRMDHYEPELHDVPPDDPADTTTPQAIATDFRDLLLGTALPVRERR -LLMGWLSRNATGARRIRAGLPGDWKVADKTGTGDYGRANDIAVVHPPRTGPLVLAVMTDR -PGRDAEPSDALIAEATRRTV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mobaraensis TaxID=35621 RepID=UPI0003466F80 ----VAERLRALEEAYHGRIGLAAFDTGSGRSV-TYRAHERFALCSTFKFLAAAAILDKAR -RDPGLLDRPVRYS--EVIDGSPVTKDNLSRGMTVRELCDATIAVSDNTAGNLLLEQLGGP -RAIGAFARTLGDRRTRLDRTEPTLNTNLPGDPRDTTTPAAMARDVYALTVGTALAAPDRE -QLNRWLEGCRTGDARIRKAMPAGWLVGDKTGTGERGAANDIAVVRPPGRAPLVVAVYTTR -VGGTETGDSEIIARAAGM----- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia territorii TaxID=1503055 RepID=A0A108ERE2_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRV-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTAMLQSGDKGAGNVLMGVLGGP -QAVTGFAHESGDTVFRLDRWEPELNEAAPRDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGARNASGIAAGVPPGWRIADKTGIGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIATGAf ->[subseq from] L2 family class A beta-lactamase n=2 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A6B8IWP0_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas pavanii TaxID=487698 RepID=UPI0013E08173 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A0A4S0VGZ2_9RHIZ ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces mobaraensis NBRC 13819 = DSM 40847 TaxID=1223523 RepID=M3BGD5_STRMB -----AERLRALEEAYHGRIGLAAFDTGSGRSV-TYRAHERFALCSTFKFLAAAAILDKAR -RDPGLLDRPVRYS--EVIDGSPVTKDNLSRGMTVRELCDATIAVSDNTAGNLLLEQLGGP -RAIGAFARTLGDRRTRLDRTEPTLNTNLPGDPRDTTTPAAMARDVYALTVGTALAAPDRE -QLNRWLEGCRTGDARIRKAMPAGWLVGDKTGTGERGAANDIAVVRPPGRAPLVVAVYTTR -VGGTETGDSEIIARAAGM----- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Sulfitobacter TaxID=196795 RepID=UPI00055ADDED ---TLTNTVAQIEERLGARVGVSLLETGSELSW-AHREDERFMMNSTVKAPICGAVLARVD -ADEMSLTDTLNVQKDDILSYAPVTEKQVGTAMSLADLCLAAIDLSDNTAANMLLDHIGGP -QAVTEFFRQTGDEVSRLDRREPELNEFVPGDPRDTTTPAAMTKMLRGLLLGNVLSPSSRE -QLVEWMSIGGVTSNLLRADASKDWLILDKSGSGSH-TRNIIAVVVPEGGAPWVVSIFISD -VDADFETRNTALQQIGGAVM--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces subrutilus TaxID=36818 RepID=A0A1E5Q147_9ACTN ----AARRLRELEREHSARLGVFARDTATGRTV-AYRADERFPMCSVFKGLAAAAVLRDLD -EDGEFLARRIRYTREYVEKYGPETGKNLADGMTVEALCAAAVSLSDNAAANLLLEALGGP -AAITRFSRSLGDRTTRLDRWEPELNSAEPGRITDTTSPRAIGGTYARLLLGDALPSGDRG -RLTGWLVANTTNTGRFKAGLPADWILADKTGGGNYGVANDVGVVWPPGRAPIVMAVLTTK -PGAPAPRDEELVAKTARLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A101A5C -----DSEFAALEEQFDARLGVYAVDTGTGREI-EWRGDERFAYASTIKALAGAALLDDVG ---TAGLAKTVEISASDIIKHSPVTETRVGQSMTLDEICEAALTQSDNAAANFIFAELGGP -QAFDAQLDELGDAGTTVSRIEPDLNEALPGDFRDTTTPRASANNLREYVFGDALDDEEKT -ALTDWMKASQTGDTLVRAQLPEDWTVGDKSGGGMYGSRGDLAVVWPTDGRPIVISVLSSR -DEQEADYDDRLIAGAAAAAVDQ- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A4Z0HET2_MYCPR ----VDDQIAELERRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMVG -RKQIALDNRVFVDPEAIVPNSPITETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYHQILAGDALSPPQRR -QLDDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDPKADNPLIGELT------- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. Amel2xC10 TaxID=1305826 RepID=A0A1X7C7I7_9ACTN ---HLARRFHALERRYAARLGVHAHDTATGRTL-AYRADERFPLCSVFKTLAAAAVLRDLD -RDGEYLARRIRYTKEYVTAYAPITDENVAAGMTVAQLCAATVSHSDNGAGNLLLRELGGP -TAITRFARSLGDPTTRLDRWEPELNTAEPWRRTDITSPRAIGGTYARLLLGGVLPRGDRD -LLTGWLVANTTNTARFRAGLPADWTLADKTGGGAYGVANDVGVVWPPGRPPIVLSVLSVK -HAPEGPTDNPLVAGAAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis kunsanensis TaxID=141693 RepID=UPI0003715CCF ----AEEAFTGLEEDYDARLGVYALDTGTGQEV-EYGADDRFAYASTFKALAVGALLDQHG ---AEVLDERMDLSEEDLLTHAPIAEEFLDQEMTLREASDAAVRYSDNTAANLVLERLGGP -EGYQEALREIGDDTTSADRWEEELNEAAPGDERDTSTPRAMAENLRTYVLEEPLAEDERE -FLTDLLVRNTTGDALIRAGVPEDWEVGDKTGGGGYATRNDIAVAWPPESDPVVIAVMSSR -GEQDAEYDDALVAEATETAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=UPI0004C356FC -------ALFELEKKFDARLGVYALS-NSGRTI-EHRADERFAFCSTFKGLAAAAILHRNP ---MTHLDTVVTYTEADLMKSSAITKQHVQTGMKLRDLCDAAVCYSDGTAGNLLLRDVGGP -AELTRYLRELGDTETRMDRVEPAITEATPGDPRDTATPRSLGTDYQRLVLGDALPQDKRD -FLTDLLERSVTGAKRVRAGVPQGSRVASKTGTGDYGTLNDIAVVWPPGREPILVALMSSR -SAADAKYDEALLAEAAAYVVK-- ->[subseq from] Uncharacterized protein n=2 Tax=Cellulomonas cellasea TaxID=43670 RepID=A0A0A0B9L0_9CELL -----QAAIAAIETESGLTLGVAAIDTGTGAVV-GHRADERVLLCSTAKVLVVAAALALRT -ERPGLLGEPVPIPAGQVVDHSPVTAEHEGGELPVAVLCDAAITQSDNTAANALMGLVGGP -AGVTAYVRTLGDEVTRLDRTEPELNQGAPGDERDTSTPAQVAADLRLLAVEEGLPPESRD -PLVGWMRGSTTGADRIRAGVPAGWTVGDKTGTGPNGEVHDVGVVWPPDGAPVVLAVYTSP -AAGSTEASAAVIARVAALVCEAf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE28D41 ----IVASAKRVEQKLDMRVGFTVIDTGDGTVT-GYRQDERFAMASTFKALACAAALSRGE ----AVLAKKTTIRQADLRPHSPVTEKRVGTSISTRALCEMTLRTSDNAAANAILKALGGP -AEVTGFLRQIGDETTRLDRYEPELNEARPGDPRDTTTPQAMAETLRRLLLQDVLDPQARD -RLEEWMAANAVADGLLRSRLPEGWQIADRSGAGGHGTRGVIALVRPPQGAPLVIAIYMDG -TKHPLKVRDAAIAEIGAAIFESy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis listeri TaxID=53440 RepID=UPI00082DB117 ---DVSAEFEALEEEFDARLGVYAVDTGSGDTV-AFQEEDRFAFASTFKALLAGVVLSENS ---LSEMERVVTFDEGVLVPHSPVVEENLDSGMSLLELCDAAVRYSDNAAANLLLDEIGGP -AGFTEALGSTGDEVTNLTRYEVELNEATPGEERDTSSARAMTESLEAFTLGDVLPKDRRE -VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGSGGYGTRNDIGVLWPQEGDPIVLAVLSSR -DVEDAESDDALIAQASEVVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B8SMT9_PSESP ---ALTETVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD -RDEVELDTRVRFDETDLQSYSPITKDRVGGSMSLFELCSATTSMSDNTAANLILRNTGGP -QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE -QLKAWLVNNKVGGPLLRASLPEGWKIADRTGAGGYGSRGIIAVIWPQGSEPVIVAVYLTG -TTLTLEERDATIAEVGAALV--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio parahaemolyticus S100 TaxID=1394638 RepID=A0A0I9QQ12_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQMDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSVGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAQISQLILERy ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI00096E0230 ----IDDQIAELERRHHALIGLYAANLDTGRTL-THRPDDMFAMCSTFKGYAVARVLQMAE -RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMARS -QAHDAKAENPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. TAA204 TaxID=1289387 RepID=UPI000D13861D ----IARALRELEREHSARLGVFAHNSVTGTSV-LYRADETFPICSVFKTVAVAAVLRDLD -QYGEFLAKRVRYTEQDVQDYAPVTGENLEGGMTVGELCAAAVSYSDNTAANLLLRELGGP -ASVTRFSRSVGDRATRLDRWEPELNSAEPWRTTDTTTPGAIGRTCARLTLGRALRPRDRK -RLTDWLLANTTGGARLRAGLPGSWTLADKTGTGEFGTTNDVGVAWKPDGTPLVLAVLSTK -DDAEAAADEPLIAKTAALLAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004863000 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Woeseia oceani TaxID=1548547 RepID=A0A193LDU8_9GAMM -------LLLTLEQELDGTIGVFAMDTMTGNEL-AYRADERFAMASTFKSLLVAAVLAEVD -AGTLDLEERYGIDGVDMQSYSPVVGKLAPNEISLSELCAAAITISDNTATNMLLELIGGP -DELTQFLRRSGDDVTRLDRYETALNSNDKGDERDTTTPRAMTHSMYRLLTSDLLSSASKQ -RITEWLIASQTGFSRLRAGLPPGWTVGDKTGMGRNGAANNFAIAWPPGRKPVVMTVFMSW -SDTDVDTLNVAHARIAAHIAAAf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium elephantis DSM 44368 TaxID=1335622 RepID=A0A439DZ72_9MYCO ---TVEARIAALERQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARVLQMAE -RGELSLEQSLFVDPADILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP -QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGSGYRNLLAGDALAPPQRS -RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIVYGPDGQRVLLALMTRS -QTSDAPGLRPLIGELTSLV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. PanSC19 TaxID=1520455 RepID=A0A3N1P3L8_9ACTN ------ARLRRLEREHTARLGVFARDMRTGRTV-VHRAHERFPMASVFKTLAVAAVLRDLD -RDGEFLARRVHYTRAYVTKLSPIAGENVANGMTIAELCDATIRFSDNTAGNLLLEELGGP -TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPYAIGLDHARLVLGDALDPHDRE -RLTDWMLRNTTSTEKFGRGLPADWILADKTGSPRYGGANDVGIAWRPDGTPIVLAVLSTQ -PEEDAPTDNPLVAGTAELLAEEf ->[subseq from] Beta-lactamase n=5 Tax=Stenotrophomonas TaxID=40323 RepID=B8LF98_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Moritella sp. Urea-trap-13 TaxID=2058327 RepID=A0A2I0FC53_9GAMM ---TLNDSLSAIELRTSGRIGAAVLDTENKQIW-HYNGDARFPMMSTFKTLACAKMLSASA -NGELNTSTKILLKSEALIPWSPVTKPLVGSSITVAQACEATMLTSDNTAVNIVLQHVGGP -EGVTAFLRDIGDNVTQLDRIEPELNEAKIGDVRDTTTPNAMVNTLNKLLFANVLSNRDKT -QLKTWMQDNKVSDPLLRSVLPPGWSIADRSGAGGYGSRGITAVIWHAERQPLIISIYLTE -TELSMAERNQVIAEIGQQILNQy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Root264 TaxID=1736503 RepID=UPI0007C6B42A ---ALSRRLRDLERRYSARLGVFALDTATGRTA-EYRADERFPLCSVFKTLAAAAVLRDLD -HDGAYLARRIHYTEKDVTDYAPVTGENIAGGLTVEELCAAAVSESDNGAANLVLRELGGP -TAITRFCRSLGDRTTRLDRYEPALNSAEPWRRTDTTRPRAIGLTYARLVLGRALESADRR -RLTGWLIANTTNTERFRAGLPDDWTLADKTGGGQYGVANDVGVVWPPGRPALVLAVLSTK -HDPAGPTDNPLVAKAAALTA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces indicus TaxID=417292 RepID=A0A1G9IZJ9_9ACTN -----EAEFRSLEREFDARLGVFAVDTADGREL-AYHADERFAYCSTCKAFLAAAVLDKGG ---VGGLDREVAVRRADVEGWSPVTEKNIGSRMTLRALCDAAVRHSDNGAANALFHELDGP -RGLQRALRAIGDETTRCDRYEVELSEARPGDERDTSTPRALARSLRQYALGDVLDAEGRG -LLTDWLVRNTTGDKLIRAGAPDGWRIGDKTGNGSYGTRNDIALAWPPGGEPVVLAVMSRR -AGPDAEHDDALIARAAAAVFR-- ->[subseq from] Beta-lactamase PSE-1 n=97 Tax=Bacteria TaxID=2 RepID=BLP1_PSEAI --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea violacea TaxID=128104 RepID=UPI000B7DBF74 ------DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTRYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD -FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGQYGTVNDIAVVWPPGREPVLIAIMSSK -STADAKYDEALVAEAAAYVVR-- ->[subseq from] Beta-lactamase class A CARB-17 n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A658HE08_VIBPH --sQLNEDISLIEQQTSSRVGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAIVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Salinicoccus halodurans TaxID=407035 RepID=A0A0F7HJ33_9STAP --kNTDDAMGQIEKEYDANLGVYALDTGSGQTV-SYNADERFAYASTHKALAAGVLLQQND ---IEELGRTVEISEADLVNYNPVTEDYVGEAMTLEQLAEASLHYSDNTAGNLILEEIGGP -EGFKRALRDMGDDVTNPVRSEPNLNEFIPDDPSDTSTPRALTSSLKSLTVGDALPGEKQK -LLIDWLKGNQTGDTLIRAGLPENWEVGDRTGAATYGTRNAIAVIRPPGGEPIFLAVLSNK -DKKDAEYDDELIQRATEETI--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14D2_NAIMI4_7 TaxID=2072405 RepID=UPI000D542986 -------NFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSILVAHILSLAD -AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDPVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGDGLLPPSRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEAQRAAVLARVGAL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=A0A498AP64_9ACTN -----HDRLAELERTFDARLGVYALATNTGDTI-VHRADERFAFCFTFKGLAAAAVLHRHP ---LSHLDTVVRYTADDLMKSSVITRRHVASGMTIRQLCDAAVRHSDGTAGNLLLRDLGGP -AQLTAYARSLGDAVTRMDRTEPAITTAIPGDARDTSSPRALGTTYQRIVLGDALPPEKRA -VLRDLLERNATGTQRVRAGVPRGWTVADKTGTGDYGTVNDIAVVWPPTSAPLVIAIMSSK -ATRDAEYQQALVAEAAAYVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CMB-StM0423 TaxID=2059884 RepID=A0A2K9FQ52_9ACTN --qRATREFKELERAHDARLGVYAVDTRTGREV-AYRDGERFAFASTVKAFQAGAVLRQRK ---LSGLKKEITYDRSDLVANSPITEKHVDDGMTLGELCDAAVRYSDNAAANLLFEELGGP -KALQSFLRETGDDTSRMERIEPALSDWEPDSARDTSTPRALAGNLRAFVLGDVLGMPERA -RLAGWLRKNTTGDETIRAGVPKDWEVGDKTGTAAFGGRNDIAVVWRPDAAPLVMAVLSNA -TDRDAEPDDKLIAKAAAVVSD-- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium montefiorense TaxID=154654 RepID=A0A2R5GX76_9MYCO ---QVDDRLAELERQYGAYIGLFATDVGSGRTL-AHREDEPFAMCSTFKAYAAARVLQKAQ -RGELDLQRPVFIDPAALLPNSPVTAPQAGKTMALAQLCAAALQRSDNAAANLLLTEIGGP -PAITDFARSIGDERTRLDRWEIELNTAIPGDPRDTSTPRALGTGFQKLLTGTVLGEAQRA -QLEQWMRDNMT--SSMRAGLPPGWTTADKTGAGAYGSTNDIGMVYGPTGQRVLLSLMTRS -QSPDADALQPLIAEVTKSVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=UPI000FE1AF4B ---TVEARIAALERQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARVLQMAE -RGELSLEQSLFVDPADILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP -QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGSGYRNLLAGDALAPPQRS -RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIVYGPDGQRVLLALMTRS -QTSDAPGLRPLIGELTSLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. PanSC19 TaxID=1520455 RepID=UPI000F4A0CD1 ------ARLRRLEREHTARLGVFARDMRTGRTV-VHRAHERFPMASVFKTLAVAAVLRDLD -RDGEFLARRVHYTRAYVTKLSPIAGENVANGMTIAELCDATIRFSDNTAGNLLLEELGGP -TGITRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTTPYAIGLDHARLVLGDALDPHDRE -RLTDWMLRNTTSTEKFGRGLPADWILADKTGSPRYGGANDVGIAWRPDGTPIVLAVLSTQ -PEEDAPTDNPLVAGTAELLAEEf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AU17457 TaxID=2015349 RepID=UPI000B79D31F ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMSVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDVLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pseudomultivorans TaxID=1207504 RepID=UPI000756FBBC ---AAQSDLAALEKASNGRLGVAALDTSNGARV-AHHARERFPLCGTYAVVAAAAVLARGS -LDATLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QTVTSFAHESGDTTFRLDHWEPELNAAAPGDERDTSTPVAMVDMLQRLLLGDLLREPQRA -QLIEWMVGGARGAAGIAAGVPPGWRVADKAGTGRYGTTSDVAVVWPPSRAPLVMAVSFTQ -PRADAAARADVVASAARIVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N9H029_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARANVVASAARIAA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Parvularcula flava TaxID=1566827 RepID=A0A6A8RTT3_9PROT ---------------NGGHIGVFARDIATGNSL-IHRADERFAMCSTFKWALAAQVLDEVQ -NGSITLDDEISFSEETLVPWSPVTGPLAAQGASIRTLCEAAVAVSDNTAANLLLRLVDGP -PGFTERLRGWGDEVTRLDRWETELNENAPGDPRDTTTPRAMAGLLERVAVGDIIAPAASA -TLRGWMEATSTGTNRLPAGTPDSWTLGHKTGTSNNGAVNDVGYFLRPDGAPIVIAVYVNA -PEAETTAAEVVIAEVAEMT---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium persicum TaxID=1487726 RepID=UPI000C083946 ---DVQSRFAELEHTYAARLGVYVPASGATAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDKVVTYTSADIRSTSPITQQHIATGMSIGQLCDAAIRYSDGTAANLLLAEIGGT -TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTPNAIALDYQQLVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPTGVPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf465 TaxID=1736385 RepID=UPI0006F4D2D7 -----GAALARIAGDLGGRAGIAVLDTSGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE -AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLDALGGP -AALTAYGRSLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA -RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG -SDTTSEARDAAHAAIGRVIAATy ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio rotiferianus TaxID=190895 RepID=UPI0002378115 ---KLNEDLAAIEQHIGGRIGVSVWNTQNDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -SEKLDKNATAKVEERNIVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -NGVTRFLRSIGDGATRLDRFEPRLNEAKPGDKQDTTTPNAIVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSESLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPIYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI0011F29549 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metoecus TaxID=1481663 RepID=UPI000BA956EF --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Nitratireductor sp. ES.061 TaxID=1855335 RepID=A0A1H4Q9G4_9RHIZ ---TLSQTVERIESTLGARVGIVIRDTGSDWRW-SHRAEERFLMNSTVKALICGGVLAELD -KGMLTLDQTLPIRQFDIVSYSPVTQKHVGKAMSIADLCLATLDISDNAAANLLIGRLGGP -KAVTAFLRSIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMTETWHALLLGDVLKPASRT -QLIEWMSHGGVTGALMRASLPKDWAISDKSGAGSH-TRNLVAMVTPPGRAPFLVSIFISD -TDVDFETRNGALKDVSAAIVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. ORS 3257 TaxID=167468 RepID=A0A2U3QDE8_9BRAD -------ELETYERESGGRVGLYAENLVNGKKL-AWRADERFVMCSTFKASLAAFVLGRVD -RGEEQLAAMIPYGQADLLEYAPVARENLAAGMSVGEMCKAIVELSDNTCANLLLARIGGP -AALTGFWRSLGDTTSRLDHDEPELNRSPPGNPQDTTTPAAMANNLRRLVLGEALSAQSRV -QLTEWMVNCKTGANRLRGGLPAGWKIGDKTGYNGKDAAGDIAVAWPKPDTPVLITAYVQG -GTPTPAKIAGVFAQIGRMVTD-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI0012453E24 --sQLNEDISLIEQQTSSRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRLEPRLNEATPGDNRDTTTPNAIVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kyogaense TaxID=2212479 RepID=UPI000DABF7AE ------DRLAALGRRHNARIGVYAVDLGSDRTV-EVGADDTFAMCSTFKAYASAAVLQRAQ -QGRLALTDAIAVQPSDIRPHSPVTEPRVGSTMTLAELCQAALQESDNAAGNLLLGTLGGP -PAITAFARSVGDDRTRLDRWETELNTAVPGDPRDTSTPRALGIGYRAMLTGDVLHVAHRQ -KLEDWMRANQT--SSMRAGLPDGWATADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRS -ATPDADSLRPLIGEIAAAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. col6 TaxID=2478958 RepID=UPI0011CE87B0 ---AATARLRELERLHGARVGAFAYNVATGASV-RHRAGERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVVHYTKADCVSDSPVTDTHLASGLSVARLCDAAIGDSDNTAANLLLRELGGP -TAVTRFARSLGDRVTRLDRWEPLLNSAEPGRVTDTTTPSALARDYARLVLGNALEPRDRE -RLTYWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGVPVVLAVLTTK -PASDAAGDHPLVRDAAKALA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=A0A103KGS4_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT -QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -QRADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. BH-2-1-1 TaxID=1905847 RepID=UPI0011A19B6F ----TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAALAASS ---PADLDEVVHYDRGDLLSYAPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV -AGMTRWLRGLGDTTTDVSRTEPDLNTALPGDRRDTTTPAQSAADLRAVLLGDALDADDRS -LLRDAMLGTTTGATTIRAGVDPSWTVADKTGTASYGVRNDVAVVTPPGRDPIVLVVMTAH -GTADAEPSDALVAEATRIAIAH- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3N8YP19_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMSVLGGP -QAVTAFARECGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDMLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Vibrio cholerae TaxID=666 RepID=A0A5C9HMU4_VIBCL --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0007473BC4 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DBP42 TaxID=2545267 RepID=UPI00110CE5B2 -----DDGIAELERRNNAFIGMYASNLDSGRTL-THRADEMFAMCSTFKAYAAARVLQMAE -HGEVSLENRVFVDREAIVPNSPVTETRAGGEMTLAQLCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPSALAVGYRAVLAGDALSPPRRR -LLEDWMRANQT--SSMRSGLPEGWTTADKTGSGDYGSTNDAGIAFGPEGQRLLLVMMTRS -QA-DDPKAEPLIGELTA------ ->[subseq from] Beta-lactamase n=4 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QE58_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=A0A1A3KUR9_MYCAS ---DLSHQFDQLERRYEGRLGVYVPE----PGI-AYRADERFAFCSTFKAPLAAAVLHQYP ---LDHLDKLVSYRKSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDGTAANLLLAEVGGP -AGFTTYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGDALPADKRA -LLVDWMTRNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF -VGYDAQPNEGFVADAARIVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora cretacea TaxID=28444 RepID=UPI000774458B -----VADLRALETSFKGRIGVYAVDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKEP ----DILGKRILIKKKDLLAYSPETEKHVGSRMTVAELARAAVTKSDNAAANLLLKEVGGP -KGLTRYFRGLNDHVSRLDRTEPGLNQWSPAEVRDTTTPAAIAADLRVLTVGNALDAGDRR -KFTGWLVANETGDKRIRAGLPKSWRIGDKTGTGGYGTANDYAIIWPKGSKPIIMAIYTNR -TARNGTADDSVIARAATIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis sp. KNN50.9b TaxID=2018303 RepID=A0A229TP23_9PSEU ------VSFADLESRFDSRLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVTYTDADIQPNSPITKDR--RSVTVCEAAEAALLQSDNTAANLLFAEVGGP -AGLAAVLREIGDTTTHPDRLEVELNSAIPGDIRDTSTPRAMAGSLRAFLLGDALPADKRD -LLVGIMRRNRTGAELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPTGAPIVLALMSSR -GTPDAEHDNKLLAEAASRVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=L0FSL3_PSEPU ---KLIQAVQAEESALQARVGMTVFDENTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD -GKSLSLSQSVSISKEMLVTYSPITEKSLSPEVTLGRICQAAVSYSDNTAANVVSNAIGGA -TGFNAYMRSIGDEQTRLDRKEPELNEGTPGDVRDTTTPNAIVNSLRKILLGDGLSVSSRS -ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ -TKASMQASNQAIARIGVV----- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora citrea TaxID=47855 RepID=A0A1C6TRH4_9ACTN -------RLTELERKYGARLGVYALATGTGATV-AHRADERFAFCSAFKGLAAAAVLHRNP ---LSHLDTVVRYAERDLMKSSAITRRHVATGMTVRQVCDAAVRFSDGTAGNLLLRDLGGP -AELTAYVRGLGDTVTRMDRFEPHIVTAVPGDLRDTTSPRAIGTDYQKIVLGDALPPDKRA -FLRGLLERNATGARRIRAGVPKGWTVADKTGTGDYGTVNDIAVVWPPQAAPLVVSIMSSK -AARDAEYDQELLAEAAAHVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F599D6F ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia PC184 TaxID=350702 RepID=A2VYA7_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. MBT63 TaxID=1444768 RepID=UPI00068F131A ---DVTRALAGLEREHSARLGVFARNTVTGAQV-LYRAHELFPICSVHKIVTAAAVLRDLD -HHGEFLARRIRYTAEDVAAYAPITGEHLASGLTVAELCVAALDYSDNAADNLLLRELGGP -AAVGRFCRSVGDGVTRLDRWEPALNSAEPGRVTDTTTPAAIATTLTALVLGGALTSRDRR -RLTDWMLANTTGAARLRAGLPQPWALADKTGTGDYGTTNDVGVAWTADGAPVVLSVLSTK -TDPHAPADEPLIARTAALLV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A4Q6CB32_9PROT -------DFEKLERETGGRIGVSVLDIRTGKRI-LYRSGERFPFCSTFKTIAVATALKHGD ------LSTRLTFTSDDVKKYAPITTKFVDRGMTVSELSEAAIQYSDNAAVNILMRNLGGL -QAVNTFAREIGDEVFQLDRWEPELNSAEPLDKRDTTTPDAMTGSVHKILLGDALAAFARD -LLLSWHIGNTTGDKRIRAGLPKGWTAAEKTGTCSHGTTNDAGVIWRPDGSPIVLTIYLTG -RAKDAKPDDAAVARATQIIVE-- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metoecus TaxID=1481663 RepID=UPI000BA9192D --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKRVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H2CL98_9ACTN ---AVAAALTALEDDYAARLGVYAIDTGTGQVV-EHRPDERFAFASTHKMLSAAAVLQVTE ---PADLDELIEVDPAEVVGWSPVTEPAAGVGLTLLEIIEAAITLSDNTAANLLFEQVGGP -DGLEAAVRGFGDETTSFDRIEPGLSDWAPGEERDTTTPRAMAGNLRDLLLGDLLTDEDRT -LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR -LDPEAESDPALIAAATEIVVDAf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=A0A454BGN4_VIBHA ---KINEDLAAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLNDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRIEHACEAAMLMSDNTAANIVLRSVGGP -RGVTMFLRTIGDKATRLDRFEPRLNEAKPGDKQDTTTPNAMVNTLHTLLEDDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITG -TDLSLQARDQVIAQISQLVLEEy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF88_STEMA ------ADYAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRYDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=[Actinopolyspora] iraqiensis TaxID=52698 RepID=UPI0003F515F9 ------PDFAELERRYSARLGVYALDTGSGTEI-THRADERWAFCSTIKPFTAMAVLQRTT ---LDGLDEPITYSREDLISHSPVTEQHVDTGMTLRAVLEAAVRNSDNTAQNLLLDEVGGP -AGLQRALRELGDTVSHADRYEPELNETAPGDIRDTSTPRALATNLRKLVLGDVLAPGKRT -ILREAMRNPPLTADLIQAGVPDDWQVEDKSGAGGYATRNDIAVLYPPERAPIVLVVLSDR -ARPDAEYDDTLLAEAARVTV--- ->[subseq from] Beta-lactamase n=1 Tax=Salinisphaera japonica YTM-1 TaxID=1209778 RepID=A0A423PT43_9GAMM ------ARMKTLEARHGGRLGVSVCDTTGARRL-SHRGDDRFLLCSTVKLPLAALILSRMD -AGQESLERHIDYTRADLVTYSPETEQHVATGMTLGAICRAGLTQSDNTAANLMFAAVGGP -AALTDFIRALGDATTRSNRLETALNEP-TLNAKDTTTPNAMRGLMTRILLGDVLSHGARA -QLLTWMQANQTGDHRLRAGLPSAWRIGDKTGSGGDNTAADIAIIHPGAGHAIVVSAYYAG -SRASGEARDRVLADVGRAVAELy ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. SID9727 TaxID=2706114 RepID=A0A6B3BAQ6_9ACTN -----TARLRELERTHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVVHYTKADCVSDSPVTDTHIASGLSIARLCDAAIGDSDNTAGNLLLRELGGP -RAVTRFAHSLGDRLTRLDRWEPDLNSAEPGRITDTTTPSAIARDYARLVLGDVLERRDRE -LLTHWLLHCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGAPVVLAVLTTK -PASDAAGDHPLVLDAARILA--- ->[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium HGW-Gammaproteobacteria-11 TaxID=2013793 RepID=A0A2N1ZCB1_9GAMM ---ALTDTVAFIEATTGGRVGVSITDLDSGLTW-SHRSNERFPMASTFKAFSCAHLLALAD -KGEIDLDSRVQFEESDLQDYSPITQHRVGGNMTLFELCAASTSLSDNTAANLTLQNTGGP -PAFTQFMRSIGDNTTRLDRYEPDLNYVGPGEEQDTTSPASAAKSLQTLLLGNSLSNNSRE -QLKTWLINNEVGGPLLRASLPDGWQIADRTGAGGYGTRGIVAVIWPQTHGPVVAAVYLTG -TTLTLEERNAAIADIGRALVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. Root151 TaxID=1736475 RepID=UPI0012E36F4A ------SEVAAIERRYDVTVGLSATHLRSGRTM-QHRADAPAAMCSVFKALAAAAVLRDHD -RRGETLDRRVFYPPADVLIHTPETGRHVDDGMTIRELCDAALRFSDNAAGNLLLREIGGP -RGLTAFLRSVGDGVSRLDRWETELNSALPGDPRDTTTPAAIARTYAGLLIGDTLSRRDRT -TLRDWMLANQTSDNRFRAGLPEGWILADKTGGGDYGSNNDVGVAWNPRGEPVVIAALVRG -KVADAVTPDVVHAELAALVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pararhizobium antarcticum TaxID=1798805 RepID=A0A657LTM1_9RHIZ -----GVRLAALEKKTGGRLGVSVLDTETNIGF-DYRETERFPMLSTFKTLAAACVLAGIK -DDEDALQRRVKFSKADLVSYSPGTEAFADGEMTLSALCDAAITLSDNTAGNLLLAEIGGP -QGLTAWLRSIGDATTRLDRTEPTLNESLKGDPRDTTTPAAMRETITTLLAGDVLSPSARD -RLLGWLVANKTGDARLRAGLPAGGLVGEKTGTTDKGGACDVGLFRPERRQPIFISAYVAE -ASVPVKDLNPVFAEIGRMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI00073AD3D3 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGL -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=A0A1Q8XTF8_9MYCO ----VDDQIADLERRHNALIGLYASNLDSGRVL-TRRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDREAIVPNSPVTETHVGGEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPTALAVGYREVLAGDALSPPQRR -LLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAVMTRS -QADDADNLRPLIGELTAVV---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=A0A1Q4VI00_9ACTN ---AATRRLHELEREHRARIGVFALNLATGASL-LHRAHELFPICSVFKTLAVGAVLRDLD -HDGTQLSRVIHYTEADVRKHTPVTSQHVADGMTVRALCDASIRYSDNCATNLLLRELGGP -PAVTRFCRSLGDPVTRLDRWEPELNSAEPGRRTDTTSPYAIARTYRRLVLGDALNGPDRA -LLTDWLVRSTTSVERFRAGLPKDWTVADKSGSGSYGTSNDVAVAWTPDGTPIALAAFTHK -PAL-------------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=J9UVY5_ECOLX --------IKLSESQLSGRVGLIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGI-------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q9F4G6_PSEAI --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNSNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium endophyticum TaxID=2478914 RepID=A0A3L8PPK9_9ACTN ------------ATAAGIDFGVSVTDLSSGASM-SIGSQEPVKAASVIKLPLLAALMAEAD -RGTLSLDEVVTIEASNIVGGSGTLRDETPLDITVGELMELMVQVSDNTATNVLIDRAGGF -DAVNAYIESLGFEHLWLGRKMI--HPATPPLQENWITSGEVTELLRMLHADEILSPASSE -HIIELMKGQLV-DTKFGAVVPRD-VLANKTGELAD-VSHDSGYILVPGRE-VALTVTTAF -GDLTRAEVDQYVQRAASIVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium endophyticum TaxID=2478914 RepID=A0A3L8PPK9_9ACTN ----------DAAAEAGIDIGVAIEDLSDDQQL-LLGAQDRFTTASTIKMSLAATVMHQVE -RGMLSLDDVVTITEDERYGGSGSLKDNPFPQVSVGTLLDLTVTISDNTATNKLVDVVGGF -DVINALTQAVGIAKEDLHFGRKMFGPIVPPDGDIWLTPHGVNQLMVLFYDGEFMSAESAQ -FIIELMLSQQV-KTKLGATIPAE-VLAHKTGENDT-VSHDIGMVLLPGQ-EITLSVFSRG -LPDVQATANPYLQQIGAAVYAY- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI000F800387 ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDTVQQLLLGDTLREPQRA -QLIEWMSGGTRGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAVRIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium novocastrense TaxID=59813 RepID=A0A100ZAU6_9MYCO ----VEDRLGEMERRQNALIGVFATDLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP -SGVTDFARSIGDQRSRLDRWEIELNAAVPADPRDTTTPEAIGAGYRSILTGNVLAEPQRR -QLEDWMRTNQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPAGERLLLAIMTRT -AAPDAPNDRQLVGEVAAALVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A1R1JCL5_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAALLARSA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGASGCA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADASPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=B6E3J9_SALTM --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A095FRL5_BURCE ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNQATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGNGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PEAAAAARADVVAAAARIAA--- ->[subseq from] Fri1 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A0M5L4T8_ENTCL ------EEMRELETSFGGRIGVYILNPKNGKEF-AYRQDERFPLCSSFKAFLAASVLKRTQ -EKSVSLDDMVEYSGRVMEKHSPVSEKYRKTGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNTAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS -LLQEWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDVAILWTDANSPAVMAVYTTR -PNQNDKHDEAVIKNAAKIAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000160DAC5 ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RGTENLTAQIEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLMERIGGP -EGFTDYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea turkmeniaca TaxID=103838 RepID=A0A5S4FB52_9ACTN ---NVRKELRALEKAFKGRIGAYAVDTATGKTV-TYRAGERFPLLSTFKAMACAAVLHKAR -TDPGLMNKVLHWTADEVLDYSPVTEKHVKDGLTVAQLCEATITLSDNTAGNLILKQIGGP -AGLTEYFRSLKDPISRLDRYEPGLNDWTPKDKRDTTTPAAIARDLRALTSGNALHAKDRE -QINTWLIATRTGDARIRAGLPKTWTIGDKTGTNSTGGGNDIAVIWPEKGAPIIMAIYTNR -TP-GLATDDKTIAKTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0008420A6A ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTMTDVAVLWPPSRAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Microcella putealis TaxID=337005 RepID=A0A4Q7LTV8_9MICO -----DDDLSSLEAAYDARVGVYALDTGSGDRV-AYRADERFAYASSIKAVLAAAILQEVD -----DLDRVVSYGADALVANSPETEANLATGMSIRDLAEAAVRVSDNAATNLLLAELGGP -AAFGELLASLGDTTTEPARTEPALNEATPGDTRDTSTPRALVETLRAYALGDALPDDRRA -LLIDWMTGNATGDTLIRAGAPADAVVADKSGAGGYGTRTDIAVVWPAEGDPIVIAVLSSR -AEAGAERDDQLVADAAAVALD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces scabiei TaxID=1930 RepID=A0A086GY44_STRSC ----LARQLGELEREHAARLGVFAHDTATGHTL-AYRADERFPICSVFKTLGAGAVLRDLD -RDGEYLAKRIHYTKEYVEAYCPITARNVAAGMTVGELCSASVSHSDNGAANLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPQLNSAEPWRKTDTTTPRAIGGTYARLLLGRALPDADRE -LLTDWLIANTTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVWPPLRPPLVLSVLTTK -HAPEGPSDNPLVAKVAGLVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=UPI0009A10CED ---AATRRLHELEREHRARIGVFALNLATGASL-LHRAHELFPICSVFKTLAVGAVLRDLD -HDGTQLSRVIHYTEADVRKHTPVTSQHVADGMTVRALCDASIRYSDNCATNLLLRELGGP -PAVTRFCRSLGDPVTRLDRWEPELNSAEPGRRTDTTSPYAIARTYRRLVLGDALNGPDRA -LLTDWLVRSTTSVERFRAGLPKDWTVADKSGSGSYGTSNDVAVAWTPDGTPIALAAFTHK -PAL-------------------- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI0008932FD7 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KRITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1826 TaxID=1637875 RepID=UPI0007547163 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNQATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGNGGFGTTTDVAVLWPPSRAPIVMAVSFTQ -PEAAAAARADVVAAAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A124RKU1_9BURK -----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PEATAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis ruanii TaxID=944491 RepID=UPI000E288BA3 ------VSFADLESRFDSRLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVTYTDADIQPNSPITKDR--RSVTVCEAAEAALLQSDNTAANLLFAELGGP -AGLAAVLREIGDTTTHPDRLEVELNSAIPGDIRDTSTPRAMAGSLRAFLLGDALPADKRD -LLVGIMRRNRTGAELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPTGAPIVLALMSSR -GTPDAEHDNKLLAEAASRVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas borealis TaxID=2508710 RepID=UPI00109FC74C ---DLERPLGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTCKFFIAAAVLARVD -EGRETLERRIVIEEGDLVGWTPVTEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -AAVTAYLRSIGDDTTRLDRVEPDLNTDREGDERDTTTPLAMMATLRTLMLGDALAPSSRH -QLAAWMIEGKTGDARLRAGMPASWLVGEKTGTNGEGNASDVGIAWPGDRGAVVAVAYTKM -PGATGGQRDETIATIGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. PhB130 TaxID=2485178 RepID=UPI000F4BE663 ---SADASFRRLEQQHDARLGVVAVDTGSGHRV-EYRQGERFAFASTNKTFIAAAVLAGAS ---DTDLETVVHYDRSDLLDYAPITSRFVDTGMTVRELIDASLRFSDNTAANLLVERLGGP -DSVERYLRGIGDRVTNVDRVEPELNEATPGDARDTTTPAQFATDLRKVVLGTTLELTDRT -FLRDTMLDNTTGAGTVRAGVDPAWPVADKTGTGEYGVRNDIAVVYPSGRAPLVVVVMTSG -KQSDATADDALVAAATKAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas TaxID=286 RepID=UPI0009410562 ---KLIQAVQAEESALQARVGMTVFDENTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD -GKSLSLSQSVSISKEMLVTYSPITEKSLSPEVTLGRICQAAVSYSDNTAANVVSNAIGGA -TGFNAYMRSIGDEQTRLDRKEPELNEGTPGDVRDTTTPNAIVNSLRKILLGDGLSVSSRS -ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ -TKASMQASNQAIARIGVV----- ->[subseq from] class A beta-lactamase n=1 Tax=Acuticoccus kandeliae TaxID=2073160 RepID=UPI000D3E1605 ---RLADTIARIESGLDARVGVLVRDSATDWEW-GHRSDERFLMASTFKSVLCGAVLARVD -AGDLSLSEPLAVRKAAMIAHAPVTEKHVGGTMSIGELCFATLDMSDNPAANILVERLGGT -GAVTAFARALGDPVTRLDRLEPELNLFEPGDLRDTTSPEAMLFIWEAMLRGDALSPASRA -QLDAWMSEGGVTGKLLRASTPDDWAVADKSGAGRDHTRNLVAMVTPPGRDPYFVAIYLSD -SPADFAARNAAVAQIGKAVVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Nocardioides sp. Root151 TaxID=1736475 RepID=A0A0Q7ZQ10_9ACTN ------SEVAAIERRYDVTVGLSATHLRSGRTM-QHRADAPAAMCSVFKALAAAAVLRDHD -RRGETLDRRVFYPPADVLIHTPETGRHVDDGMTIRELCDAALRFSDNAAGNLLLREIGGP -RGLTAFLRSVGDGVSRLDRWETELNSALPGDPRDTTTPAAIARTYAGLLIGDTLSRRDRT -TLRDWMLANQTSDNRFRAGLPEGWILADKTGGGDYGSNNDVGVAWNPRGEPVVIAALVRG -KVADAVTPDVVHAELAALVAD-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Nocardioides TaxID=2615069 RepID=A0A0Q7QVX4_9ACTN ------SEVAAIERRYDVTVGLSATHLPSGRTM-QHRADAPAAMCSVFKALAAAAVLRDHD -RRGETLDRRVFYPPADVLIHTPETGRHVDDGMTIRELCDAALRFSDNAAGNLLLREIGGP -RGLTAFLRSVGDGVSRLDRWETELNSALPGDPRDTTTPAAIARTYAGLLVGDTLSRRDRA -TLRDWMLANQTSDNRFRAGLPEGWILADKTGGGDYGSNNDVGVAWNPRGEPVVIAALVRG -KVADAVTPDIVHAELAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=UPI0005B48245 ---TLSDELAGLEIQSQGRLGLHVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ -RDDIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVVVSDNTAANMMLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLADSRTGDKRVRAGMPGDWKVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A506Z6T7_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDP-KAEN------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID1034 TaxID=2690248 RepID=A0A6B1NPR5_9ACTN ---DVSGALRQLEAAHDVRIGAYALDTGTGRTV-SYRGNESFPSLSTFKAMACAAVLDRAR -HEPGLLDKVVHWKASDEVANSPVTKGQGGKGMTVAELCRAAITQSDNTAGNMVLHQIGGP -QGMTRYYRSLGDPVSRLDRWEPELNDWQPGERRDTTAPASMGRDLAKTSLGRGLAPADRD -TLNTWLRATVTGGERIRAGLPKDWTVGDKTGTTDYGSANDIAVAWPKSGHPVIIAIYTNH -AVAQAPADNAVIASTASTLV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. MTM3W5.2 TaxID=1805827 RepID=A0A1P8YIE9_9NOCA --qSLDTKLDALEARYATRIGVTAIDPATGQIY-QHRGDERFALCSTFKTYAVAEVLRRTR -AGTSSLDKSVLVEPGDLVENSPITAAAVGTPMTLRQIAEAALTRSDNTAGNYLLEEIGGP -PAVTSLAREIGDESTRLDRWETELNSALRGDPRDTSTPNDLADGYRALLLGDALGSPERA -QLVDWMRASKTSDKRIRAGLPEGWTAAAKSGAGRFGTVNDAGVAWDRDSNPLVLAILTDS -LTEDAQGNNQVVADTTAAVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX9_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVLTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. CNPSo 3157 TaxID=2654983 RepID=UPI00128DD1E1 ----AHERFEQLEARSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLAVAAILKRSI -AERALLDTHIRYGETDLVANSPVTKRHLSEGMSMGDACAAALQYSDNTAANLLLTALGGP -EVLNEFARSIGDTWFDLVRREPELNDAVPGDMRDTTTPRAMMHDMQKILLNDVLEPPQRE -KLKAWLLGNTTGERRIRAAVRSGWPVADKTGSGDYGTANDVAVVYSPAAA-FVVAVYFTG -VTKETPPQNEIVDEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Litoreibacter sp. LN3S51 TaxID=2599296 RepID=A0A5B8I8Y7_9RHOB ---TLADTVAQVEERLGARIGLSLVDTGSELSW-LHREDERFLMNSTVKTPLCGTVLARRD -AGRLSLSDTLRVTQEDILSYAPVTAEQVGTEMTLADLCLAALDMSDNTATNMLIDYLGGP -QAVTEFFRTTGDEVSRLDRREPELNTLVPGDPRDTTTPAAMTSTLRRLLLGDVLSPSSRD -QLAEWMSLGGVTGNLLRADAPDDWLILDKSGSGNH-TRNIIAVITPDGGSPWIATIFISD -TDADFATRNAALQEIGSAVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5AF6AC ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf125 TaxID=1736265 RepID=A0A0Q5E821_9RHIZ -----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGTFPLCSTFKLPLAAAILARVE -AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLGALGGP -AALTGFCRDLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLSEAGRA -RLKGWMTASRTGTKRLRAGLPADWGIGDKTGSGAYGTANVVALLRPPARAPLVAAVYITG -SDATSEARDAAHAAIGRVIATAy ->[subseq from] Beta-lactamase class C n=1 Tax=Burkholderia sp. 28_3 TaxID=2183921 RepID=A0A364H505_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLPPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPARAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F5B447D ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium aphoticum TaxID=754436 RepID=A0A0J1GNG3_9GAMM ----VQTQIQAIEQTLSAHIGVAVLDTQNNTRW-SYKGDERTPLTSTFKTLACAKLLHDAE -NNTLALIDTVTIKASELVTYSPVTEKWVGKAIPVVQACEATMFTSDNTAANIVIHAVGGP -DKITAFLRQSGDAVTQLDRFEPALNEATLGDVRDTTTPNAMTQTLNTLLFKNGLSKQNQQ -QLIDWMVGNQVTGNLLRSVLPQGWTIADRSGAGGHGARSITAVVWPEDRAPVIIAIYVMQ -TEASFDARNQAIVTIGQAIFNLy ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066E12DD ---SAKKELRALEASFRGRIGAYAVDTATGKTV-AYRSGERFPLLSTFKAILCGAVLHKAR -TEPGLMDKVLRWTSDDLVAHSPVTEKHVKDGLTVAALCEATITTSDNTAANVLLKEIGGP -GAVTRYFRTLKDPISRLDRTEPTLNDWAPKEKRDTTTPAAAARDLRALTAGSALHAKDRE -RLNAWLIANQTGDARIRAGLPRTWRIGDKTGTNGRGLANDIAVVWPAKAAPIIMAIYTNR -ADPADAVDDKIIAGTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=UPI00050F2EE9 ---TLSDELAALEIQSQGRLGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQDLCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQVMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPDDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides abscessus TaxID=36809 RepID=UPI0009A72A19 ------NELASLEKDFVGRIGVYALDTGSGDTV-SHRTDERFLMCSTVKTFIVSAILHRSL -SEPGLLDRRIQYTQSDVLEWAPITSQHVPTGMTVSELCDATLRYSDNTGANLLIAQLGGP -KETEKFVRSLGDNVSRMDRTEVQLN--IPDGDLDTSTPQQLVANLRRLVLDEGLDSGGRD -LLTDWLKRNTTGDQSIRAAVPAGWTVADKTGGGFKGETNDIAVIWPPDRAPIVMAVLTVP -EDPTSTKGKPTIAAAARIVLRAf ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces mobaraensis TaxID=35621 RepID=A0A5N5W933_STRMB ----VAERLRALEEAYHGRIGLAAFDTGSGRAV-TYRAHERFALCSTFKFLAAAAILDKAR -RDPGLLDRPVHYA--EVIDGSPVTKDNLPRGMTVRELCDATIAVSDNTAGNLLLEQLGGP -RAIGAFARTLGDRRTRLDRTEPTLNTNLPGDPRDTTTPAAMARDVYALTVGTALAAPDRE -QLNRWLEGCRTGDARIRKAMPAGWLVGDKTGTGERGAANDIAVVRPPGRAPLVVAVYTTR -VGGTETGDSEIIARAAGM----- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea kentuckyensis TaxID=360086 RepID=UPI000A3D379B ------EALFELEKKFDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MTHLDTVVTYTQADLMDSSKITSRHVQTGMKLRDLCDAAVRYSDGTAGNLLLREVGGP -AELTRYLRELGDNETRMDRIEPDITSATPGDPHDTATPRSLGTDYQRLVLGDALEPEKRD -FLRDLLERSVTGAKRIRAGVPQGSRVASKTGTGDYGTANDIAVVWPPSREPILIAIMSSR -SSADAKYDEALIAEATAYVAK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. paromomycinus TaxID=92743 RepID=A0A401WG83_STRRY ------------EREYGARLGVYALATGTGATV-VHRADERFAFCSAFKGLAAAAVLHGNP ---LSHLDTVVTYTEDDLMKHSPITGKHVSTGMSIRRLCDAAVRYSDGTAGNLLLRDLGGP -GKLTAFARGLGDPVTRMDRTEPAITQATPGDPRDTTSPRAFGTDYRKLVLGTVLPADKRE -FLRDLLVRNATGAQRIRAGVPKDWVVADKTGTGDYGTLNDIAVAWPTGSPPLVISIMSSK -PAKDAAYDQRLLARAAEYVVA-- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000BA8F8BF --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter pseudonitzschiae TaxID=1402135 RepID=A0A073J4Q4_9RHOB ---ELEQTVDRIEARLGGRIGIALVDTGSDFTW-ANRPDEQFLMNSTVKVPLCGAVLARVD -AGTLSLTDELPVTEGDIVTYAPVTEQHVGQSMNMAALCLAAIDMSDNTAANLLIEHLGGP -QAITQFFRSTGDIESRLDRFEPELNTFTPGDPRDTTTPVASADTVRNLLLGDVLSENSRK -QLADWMRHGGVTGKLLRAGAPADWQIYDKSGSGSH-TRNLVAMVIPDGRAPWIVSIFISD -IDADFETRNAALQDISRAI---- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Tallahassee TaxID=356544 RepID=Q2I724_SALET --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLSKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A378UA58_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDP-KAEN------------- ->[subseq from] Beta-lactamase n=1 Tax=Tardiphaga sp. CF115 TaxID=2135486 RepID=A0A370QTH6_9BRAD ----APAALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID -RGEDKPDQMISYAAADLLEYAPVARDNLAKGLSVADMCKAIVELSDNACANMLLARVGGP -AALTAFWHRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGDVLTPASRA -QLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG -GTPTAPQLETVFTAIGEMV---- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 7K507 TaxID=2530365 RepID=A0A4R4UEL8_9ACTN ---AVDKEFRALEKNRQVRIGAYAIDTGDGRAV-GYRAGERFPFLSTFKAVVCGAVLQKAR -RDPGLMDRVIRYKESDLVDHSPVTEKHVKTGMTVAELCRAAIVVSDNTAANLVLKQIGGP -AGDTAFFRSLGDRHSRHDRWEPEANDWKPGEVRDTLVPRGWAHGLRTLTTGNALAPADRT -RLIGWMKATESGADRIRAGLPEGWTAGNKTGTGGYGTANDTAIAWPPSGAPLIIVVTTNR -RAADGTEDPAAIAKAASALVR-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium shinjukuense TaxID=398694 RepID=A0A1X0JUK8_9MYCO ---DLTGHFAELERKYQARLGVYVPASGATAAI-AYRADERFAFCSTFKAPLVAAVLHQFP ---LTHLDKVITYASNDIRSTSPITQQHVDTGMTVGQLCEAAIRYSDGTAANLLLADIGGT -AAFTSYLRGLGDQASRLDQEEPELNRNPPEDHRDTTTPRAIALVFQQLALGDALPPDKRA -MLTDWLARSTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPGGAAQVVAIMSDR -VTYDAQPSEALIAAAATRIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas testosteroni TaxID=285 RepID=A0A5A7MD29_COMTE ---TLSDELAALEIQARGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVHELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDSTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWKAGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SQLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=4 Tax=Proteobacteria TaxID=1224 RepID=UPI000BA2848C ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAG--------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis taihuensis TaxID=260084 RepID=A0A1G4S2H7_9CAUL -----AQRMIEIQKRHGGRVGVSALNAEANGSL-SIQSNDHFAMCSTFKWVLAAAILQQVD -QGKLNLSDPVRYGKKDLLEYAPTTTANVAKGMTIGELCLAAVSLSDNTAANLLFPLIGGP -AGLTTFVRGPGDTVTRFDRTEPSLNTNIDGDEKDTTTPEAMSTLLRMVFTGSVLKPESLK -SLKDWMVATSTGDARIRAGVPKGAVVADKTGTGANNATNDVGVIWLPNRPPVFLSIYTSG -GSLDADGRNAVIADITRLVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F59E3F1 ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKVAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDVAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000E0D0DEE --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Paucibacter sp. KCTC 42545 TaxID=1768242 RepID=A0A0U3EZR1_9BURK --sELQARLDALQKRSGGRIGLFALNSGSRAQI-AFQADQRFAFCSTFKLLLAAAVLARVD -AGQLNLDKPIRYSSNDMLAHAPITSARLVNGMSVGELCEAIVTVSDNPAANLLFPLVGGP -PGLTRFLRELGDPHTRSDRIEPALNSNQAGDERDTTTPAAFVNSMEALLLGNRLSEEALQ -LLVGWMVGSTTGLQRLRAGLPEGWRAGDKTGTGAGGAVNDVAIAWKPEQAPLLMAVFMSG -SAQSVDELNAIHAELAGLVVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1KXJ7_MYCCH --------LASLERDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLLEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea sp. NEAU-D13 TaxID=2714351 RepID=UPI0013FA2BF4 ----LTGKLRELERLHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIVAAAILRRDH --DGTLLGKVIRYTKDDCEKYAKITEKNLANGMTVSALCEATITYSDNCAANLLLKELGGP -TAITRFSRSIGDPVTRLDRWEPELNSAEPGRITDTTSPRAIGQSYARLTLGHALNRADAG -QLTNWLLANTTGDHRIRAGLPAAWRWGDKTGSGKYSTTNDVGIAFPPGRAPIVIAVLSTK -KDPEGGADEPLVAKTAELVAASf ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium attenuatum TaxID=2341086 RepID=A0A498Q537_9MYCO ---DLQNRFAELEHRYAARLGVYVPATGTTSAI-AYRADERFAFCSTFKALLVAAVLYQYP ---LSHLDKVVTYTSADIRSTSPITEQHAATGMSVGELCDAAIRYSDGTAANLLLAEVGGT -SGFTGYLRGLGDSVSRLDQQEPELNRDPPGDERDTTTAHAIALDYQQVVLGDALPPDKRA -MLTDWMARNTTGAHRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAIVSDR -ASYDAEWSEALVADAARCVA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. NRRL S-836 TaxID=1519492 RepID=A0A0N0A442_9NOCA ------DRLVALEQKFGARLGVFASR--GDRTV-EHRADERFAFCSTFKGLAAAAVLSRAV -----PLDTVVRYTEAELMKSSQITRRHVATGMTVRELCDAAVRYSDGTAGNLVLRTAGGP -AELTAYLRGLGDEVTRMDRVEPDITSAVPDDPRDTSSPRALGTTYRKLVVGNALPDAHRA -FLRDLMERNTTGGQRIRAGVPKDWKVADKTGTGSYGTVNDIGLAWPPTGEPLLIALMSSK -PAEDAAYDQALLAEAAAYVVT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QD28_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVVRRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C95922 -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLSRVIRYTEADVTKHAPVTKDHIGTGMTVRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=UPI0008690385 ---RISRRLRDLEREHSARLGVYARNMVTGKTV-AHGADERFPMCSTFKTIAVAAVLRDLD -HDGTFLAKRIHYTAEYAKAYDKITGQNVTNGMTVEELCGAAISYSDNAAANLLLNELRGP -TAVTRFCRSIGDGTTRLDRWEPELNSAEPGRITDTTPPRAIGRTYARLVLGNALAPADRK -RLTGWLLANTTSDEKFRAGFK-GWTVADKTGSGSYGTTNDVGVVWTPKGSPIIVSVLTTK -HEADAAADGALVRRAAELL---- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea gerenzanensis TaxID=93944 RepID=A0A1M4EC41_9ACTN ---TVKKELRALEAAFKGRIGAYAVDTATGRTL-AYRAGERFPMLSTFKAPLCAAVLHRAR -TQPGLMSRHIKWTAADMKPNSPVTEKHVKDGLTVSELCVAAVTQSDGTASNLLMKLIGGP -AGMTAFFRTLKDPISRMDRWHPELNDWTPKDRRDTTTPAAMAADLRALATGTALHAKDRE -QLVAWLLASKVGAERIPAGLPKTWTIAHKTGTNSFGGGNDIAVVWPKRGAPIIMAVYTNR -TP-GLPTDNQTIARTATVLAK-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf104 TaxID=1736254 RepID=A0A0Q4ZPN3_9RHIZ ---EAEAALARIAGELGGRAGIAVLDTGGGPAL-LHDAEAAFPLCSTFKLLLAAAILARVE -AGRERLDRRLAYGAADLDAYAPVTGGALRAGMSVEALCAAAMVWSDNTAANLLLGALGGP -AALTAWCRDLGDPATRLDRTEPDLNSAVPGDPRDTTRPATMAATVAKILLGPTLTEAGRA -RLEGWMTASRTGTKRLRAGLPASWGVGDKTGTGSNGTANVVALLRPPARAPLVAAVYLTG -SDAPSEARDAAHAAIGRVIAETy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A1277 TaxID=2563103 RepID=A0A4S2RR44_9ACTN ---SATARLRELERVHGARVGAFAYNVATGVAV-RHRAEERFPMLSTFKTLAAAAVLRDLD -RDGEVLDKVIHYTEADCVSDSPVTGTNIANGLSVARLCDAAIGDSDNTAANLLLRELGGP -GAVTRFARSLGDRVTRLDRWEPELNSAEPGRVTDTTSPGALARDYARLVLGNVLEPRDRE -RLTEWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYASCNDVGVAWTPEGAPVVLAVLTTK -PGGDAAEGDHLVREAAAAL---- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. YAU14D1_LEIMI4_1 TaxID=2072407 RepID=UPI000D5421C9 -------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPITERDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDRVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGSGLLSPSRL -QFADWLIDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ARVDEAQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) TaxID=339670 RepID=Q0B8E1_BURCM ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDTVQQLLLGDTLREPQRA -QLTEWMTGGTRGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAVRIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus proomii TaxID=84407 RepID=UPI000985CCCA --------FRMLEEEYDAKLGIYALDTGTNQIV-SYRAEDRFAYASTHKVLSVGVLLQQND ---INKLEEGILIEEDDLVNYNPITEKHVGEQMTWREISDASIRYSDNAAANHILEQIGGP -EGFKKALRDIGDDVTNPERIEPYLNQVKPGETRDTSTPRALATSLLSFTIGDALTKEKQD -LLVDWLKRNTTGDNLIRAGVPKGWEVGDKSGSASYGTRNDIGIIWPPNEDPIILAVLSSQ -DEEDAEANDELIAKATEKVI--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces coeruleorubidus TaxID=116188 RepID=A0A5J6I7N3_STRC4 -------RLADLEREYGARVGVYALATGTGATA-VHRADERFAFCSVFKALAAAAVLHHRS ---LDGLDRRVTYTRADLKSTTPITGRNVATGMTLRQLCDAAVRHSDGTAGNLLMRDLGGP -AKLTAYLRGLGDTVSRMDHYEPELHDVPPDDPGDTTTPRAVATDFRKLLLGTALPAGERA -LLTDWLSHNATGARRIRAGLPKDWQVADKTGTGNYGRANDIAIVRPPRTEPLVLAVMTDR -PGYDAEPSNALIAEATAR----- ->[subseq from] L2 family class A beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=A0A6B8HW58_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVVRRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] BlaL family class A beta-lactamase n=1 Tax=Streptomyces sp. NHF165 TaxID=2175864 RepID=UPI00132F1437 ---AHEKEFRALEKKFDATLGVYAIDTADGQEI-THRADERFAYGSTFKALQAGAILRKFS -AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVRYSDNTAANLLFDQLSGP -KGLNAVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE -QLNDWMSGNATGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG -DTQDAEPHDELVAEAASVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Tardiphaga sp. OV697 TaxID=2135487 RepID=A0A2U0U8U5_9BRAD ----APTALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAAFVLARID -RGDDKLEQMISYAAADLLQYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP -AALTAFWNRTGDSISRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGDVLTPASRN -QLTDWMVNCKTGDKRLRAGLPKTWKVGDKTGNNGKDAAGDIAVTWPKPDQPIVIAAYTQG -GAPTAPQFETVFKAIGEMVG--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A0958 TaxID=2563101 RepID=A0A4S2TSB2_9ACTN ---STSARLRELERAHGARVGAFAYNAATGVAV-RHRADERFPLLSTFKTFAAAAVLRDLD -REGEVLDKVIHYTEADCVSDSPVTGTNIANGLSVARLCDAAIGDSDNTAGNLLLRELGGP -GAVTRFARSLGDRVTRLDRWEPELNSAEPGRITDTTSPASIARDYARLVLGSALEPRDRE -RLTEWLLNCRTSGTRFRAGLPPEWTVADKTGGGPYGSCNDVGIAWTPEGAPVVLAVLTTK -PGPDAAGDHPLIREAAGMLA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=A0A379BXU4_9NOCA -----HDRLFELERKFDARLGVYALDTASGATI-AHRADERFAFCSTFKGLAAAAMLHRNP ---MSHLDTVIRYTDEDLTKNAAITPQHVATGMTIRDLCDAAVRYSDGTAGNLLLRDIGGP -AELTAYLHGLGDPVTRMDRIEPAITEATPGDLRDTSSPRALSTDYQRIVLGDALPGGKRA -FLRDLLERNATGAGRVRAGVPPGWQVADKTGTGDYGTLNDIAIVWPPERAPLVISLMSSK -ATAAAEYDQALLAEAAAYVVK-- ->[subseq from] Beta-lactamase n=2 Tax=Tardiphaga sp. OK245 TaxID=1855306 RepID=A0A1H6NH51_9BRAD ----APAALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID -RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP -AALTAFWNRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPTAMAGNVKRFVTGNVLTAASRD -QLTDWMVNCKTGDKRLRAGLPKSWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG -GTPTAPQLETVFTAIGEMV---- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A3S9NKD9_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCAAMLQAGDKGAGNLLMGVLGGP -QAVTAFAHESGDTTFRLDHWEPELNRAVPADERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium aphoticum TaxID=754436 RepID=UPI000B262FEA ----VQTQIQAIEQTLSAHIGVAVLDTQNNTRW-SYKGDERTPLTSTFKTLACAKLLHDAE -NNTLALIDTVTIKASELVTYSPVTEKWVGKAIPVVQACEATMFTSDNTAANIVIHAVGGP -DKITAFLRQSGDAVTQLDRFEPALNEATLGDVRDTTTPNAMTQTLNTLLFKNGLSKQNQQ -QLIDWMVGNQVTGNLLRSVLPQGWTIADRSGAGGHGARSITAVVWPEDRAPVIIAIYVMQ -TEASFDARNQAIVTIGQAIFNLy ->[subseq from] Class A beta-lactamase n=1 Tax=Pantoea alhagi TaxID=1891675 RepID=A0A1W6B9K6_9GAMM ---TLTQKLAGLEKASGGRLGVAWID--GDRRY-GYRANERFPLTSTFKALAVSAILHKSV -SQPGLLEKKVMINNADNVPWTPVTGNYIGKAMSIGALCAATIEYSDNLAANYLLHELGGP -QGVTAWARQLGDRITRLDRYEPDLNSAVPGNQRDTSTPAAMASNLNQLALGDILPVKQRQ -MFNRWLKQNTTGDESIRAGVPEGWVVGDKTGAGEYGTTNDLAVLWPDKAQPKILAIYFTQ -PQRKAASNKAVLAAATRAVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces laurentii TaxID=39478 RepID=A0A160P6W0_STRLU --------FGELERAYDVRLGVYALNTGTGATV-VHRPAERFAFCSTFKTLVVAAVLRADS ---PIHLDKRVRYGWSDIDSVSPVTREYVAEEMTIRQLCDAALRYSDGTAANLLLRELGGP -DRLNAWLRGLGDTVSRLDHDEPELNRMRPGDPADTTTPQAIAADYRRIVLGDALSDDRRA -LLTDWMERKANGGNPIRACLPRGWRIADRTGAGDYGRTHDIAVVWPPRSAPLVLAVMSER -SRRADSPREAVLTEATRHIT--- ->[subseq from] class A beta-lactamase n=1 Tax=Tatumella sp. TA1 TaxID=2487345 RepID=UPI0008F8B4B7 --eNISAQLAQLEASVPGRLGVYLIDPIHNDSY-SYKGDERFPFCSTGKVLVVAKLLHDSQ -TNPLTMNIAMTIQQNDLTNYNPITGQNVGKRMTVSTLSQAALQYSDNTAMNLLLRQAGSI -GAINAFARTLGDRLFLLTRNEPSLNTSLPGDERDTSTPYAMAHTLQKLTLGNGLEKDKRD -LLTQWMKGNTTGNASIKAGVPTNWTVADKTGSGDYGTTNDVAVMWTEKHNPIILVVYFTQ -FQQDALPRKDVLAKAANIVTS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum viride TaxID=1231134 RepID=UPI000DC3AFCE ---ALADTIARLETALPARIGVAIRDSGSDWGW-SHRDSERFLMASTFKSVLCGAVLDRAD -RGLLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLAALDMSDNTAANLLIDRLGGP -QEVTAFLRRIGDPVTRLDRTEPGLNLFDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA -RLADWMSHGSVTASLIRASTPPDWTVSDKSGGGRDYTRNLVAMIQAPGRAPVIVAIYLSD -CPADWATRNAAVAEIGAAVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia acaciae TaxID=551276 RepID=UPI0012EEC317 --------FSSLERKYSVRLGVYAVDTGSGAFL-EYRADERFAFCSTFKTIAVAAVLWQRP ---LSYLDTVVRYTKADVNSISPIADKHVDTGMTVGQLCDAAIRYSDGTAGNLLMRDIGGP -AQLTAYLRGLGDPTSRMDQYEPDLNSDPPGDPRDTSTPRALAGDHRAIVLGNALPPEKQS -LVKDWLRRSATGAQTIRAGVPAGWTVAGKTGHGDYGRANDVAVVWPPNGAPLVIAVMSDR -AGFSDEPRYPVIADVAAHVT--- ->[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio desulfuricans TaxID=876 RepID=Q8KVT3_DESDE --kTLQKKLAELEAASGGRLGVAARSSNGGKSL-SYRGDERFPMCSTFKVLAVAALLRDKP ----GILEQRIHFAQIDIQPWSPVTEKHLEDGMTVAELCAAMLQHSDNTAANLVLAKLGGP -QGLTSLARSFGDTTFRLDRWEVELNTAIPGDARDTTTPLAMCNTLNGLLCGNLLKAPARE -RLTGWMLGCATGAGRIPAGIPQGWRSAHKSGSGENGTANDVGVLLPPKGKPLTVALYLTG -SRLTGPENDKILASATRLVC--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=A0A3P0CLY0_9BURK -----RAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PEATAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Salmonella enterica TaxID=28901 RepID=A2TJ36_SALTM --qQVEQDVKAIEVSLSARIGVSVYDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011550EEB ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAC--------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia terrae TaxID=311230 RepID=A0A2I8ELI3_9BURK ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERSLLDERVRYGDADLVANSPVTKRHVGEGMTIGELSAAALQHSDNTAAKLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVVAVYFTG -VMKQTLPRDEVVVEAARIVFD-- ->[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A5C9Q9M4_VIBCL --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVTWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000A0F58F5 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVTWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=A0A1I6D0Z3_9PSEU ---TVTGKLRELEKQHNARLGVFATDTGSGRTV-LHRADELFPMCSTFKTIAAAAILRKDR --DGTLLNKVITYTKSDVDKYGPITGRNLANGMTVSALCEATITYSDNCAANLLLKELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRVTDTTSPRAIGQSYARLTLGHALNSNDSD -QLVKWLLANTTGGNRVRAGLPAAWGWGDKTGTGKYSTTNDVGIAFPPGRAPIVIAVLSTK -KDPEGGADEPLVARTAELVAAQf ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis thermalba TaxID=944492 RepID=UPI000E235A54 ------VSFADLESRFDSRLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVTYTDADIQPNSPITKDR--RSVTVCEAAEAALLQSDNTAANLLFAEVGGP -AGLAAVLREIGDTTTHPDRLEVELNSAIPGDIRDTSTPRAMAGSLRAFLLGDALPADKRD -LLVGIMRRNRTGAELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPTGAPVVLALMSSR -GTPDAEHDNKLLAEAASRVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Alteromonadaceae bacterium M269 TaxID=2546219 RepID=A0A4V2ZG83_9ALTE ----LAKMLDALEEQYGGSFGLSILDVETQKQF-SINGDMRFPMMSTFKSLACAKLLHDAE -NGKQSLKATHLIQKQDIVTYSPVMKKKVGDEIALIDACAVTMKTSDNAAANIVLSETGGP -ADLTSFMRAMGDKITRLDRYETELNSAIAGDERDTSTPNAMTKAYYQLLYGDVLSEASES -QLTDWLKSNEVGGSLLRSVLPNGWSIGDRTGAGENGSRGIVAVVWPQDRSPFIVAIYMTQ -TSASFKERNQAIADIGRVIF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces yanglinensis TaxID=310779 RepID=A0A1H6D5E7_9ACTN -----SRSLAALESRFHAHVGLFALDTGSGRTV-AYQADRRFAHCSTVKVLAAAVLLKRES ---DAGLDRVITYPSSDLVTYSPVTSKHAGTVMPLRDVIDAALRYSDNTAENLMLDQLGGP -PGLQKAVHALGDTTTRVDRPEPALNDATPGDVRDTSTAGALGADLRRLLLGDVLPAERRS -LLVDLMVRNTTGGPYVRAGVPAGWKVADKTGSGGYGTRNDIAVAWPPHGSPVVISVLTDR -GATDAASADALVADATKAALT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces gancidicus BKS 13-15 TaxID=1284664 RepID=M3DA14_9ACTN ----------------------FAVDTGTGATV-VHRADERFALCSTFKTLAAAAVVDRRP ---GARLDERVSYSTADLVTYSPVTEKHTADGMTLRQLCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHVEPELNSNPPGDPRDTTSPRAIAADYRALVLGDALPAAGRA -LITDWLVRNTTGDRRIRAAVPRGWRVGDKTGGGEWGRGNDVAVLWPGGRPPLVLSVLTER -TDRAASPSDELVAEAARRVLD-- ->[subseq from] Beta-lactamase (Fragment) n=11 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A2L1J0Y1_ECOLX ----------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. P16(2019) TaxID=2597270 RepID=A0A553ZWU7_9BACI ---SLEEQLSKLEEEYDARLGIYAFEAGGETAV-AYQEDERFAYASTHKALAVGVLLQQKT ---MEELEKRITYTEEDLVTYSPITEQHIDTGLTLKEISDASIRYSDNSAANFIFDEIGGP -EGFAQSLREIGDDVTQPERIETELNDVKPGETRDTSTAKALAESLYTFSVGDGLEEEKRE -LLNDWLIRNTTGDHLIRAGVPEEWKVGDKTGSAAYGTRNDIGVIWPPDSEPIIIAVLSSR -DQEEADTDDELIAKATEEVIKRf ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. 9128 TaxID=1793722 RepID=UPI0011A8ED72 ----SNQAFAALEREHDARLGVTAIDTGSGHRV-TYRQDERFPFASTNKTFIAAAVLAHDS ---DADLDTVVHYDRSDLLAYAPVTSRFVATGMTVRELIDAAMRFSDNTAANLLVERVGGP -AAVEQWLRGIGDRVTNVDRTEPDLNQATPGDERDTTTPAQFASDLRSVILGSTLGATDRT -FLRDTMLDNTTGAATVRAGVDSAWPVADKTGTGEYGVRNDIAAVYPAGRAPVIVVVMTAT -DRSGATADDALVAAATKQAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Nafp2/4-1b TaxID=2116686 RepID=A0A495YSH1_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVTAAAILARGS -LDASLLPRRILYRRYDVVAGSPVTENHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTVFRLDHWEPELNRVAPGDERDTSTPVAMVDQLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRIADKAGSGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PSADAAARADVVASAARIATGAf ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea coxensis TaxID=404386 RepID=UPI00037278E2 ---QVTKELRALEKSYKGRIGAYAIDTATGRTV-GYRSGERFPLLSTFKAPVCAAALHKAS -TSPGLMDKVVKWTKADLKPHSPTTEKHVEDGLTVAQLCEATITLSDNTAGNMVLKQVGGP -AGLTRYFRSLKDPVSRLDRWETELNDWTAKERRDTTTPAAISRDLRLLTWGDALNAQDRR -RLNGWLRANQTGDARIRAGLPKSWTIGDKTGTNEIGGANDIAVIWPDKGAPIIMAVYTTR -STPS--VDDKVLAKTATVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus saganii TaxID=2303992 RepID=A0A372LRF0_9BACI -----MEKFEQLEKQYDARLGVYAIDTGTKETV-AFREDERFAYTSTSKALAAAVLLKQNP ---ISVLEEIRTFTNEDIVTYSPITEAFVNKGMSLGKIAEAAMQFSDNTAGNLLFEELGGP -DGFEKALRESGDTITMADRIEPDLNEAIPGDSRDTSTPKALAINLEVFGISEYLPADKQE -IFTHWLKGNTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIGIVWPPNREPIIIAIMSSR -NEENASFNDELIAKATKVITQAf ->[subseq from] Beta-lactamase n=1 Tax=Halomonas halmophila TaxID=252 RepID=A0A4Y4EWV4_9GAMM --tDLKQRLAELERAEGDRVGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -EGSETLDRRIAIEEGDLVGWTPITEKRLGEPLTIAELCQAAVAWSDNAAANALTESVGGP -AAVTAFLRSIGDDTTRMDRVEPDLNTDHEGDERDTTTPLAMMTTLRTLMLGDALTPSSRH -QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGEGNASDIGIAWPGDRGAVIAVAYTLM -PGATGEQRDETIAAVGRLAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=A0A5D9AKU1_9BURK ---TLSDELAALEIQAQGRFGLYVLDAVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTEQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] Beta-lactamase n=2 Tax=Rubidibacter TaxID=582491 RepID=U5DGZ8_9CHRO ---DLIATVRQIEAALDARVGIAVYDKETDRNW-QYHADERFPMNSTFKTIACAALLSLVD -SAQEKLDRIVVFDESDLVDYSPITETRFGPPMTLDELCEATMSVSDNSAGNFVMEAIGGP -EAITQFMRSIGDEVSRLDRWYPSISESVPGDKRDTTSPNSMAMMLEQLVLKQTLSLGSRQ -KLENWLKGNEVSDNLFRAVIPSDWDIGDRSGAGQYGSRSIAAIMWPPQREPVVAAVYITE -TEASFAERNAAISEIGEEIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI000F5A9D3B ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT -QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTMTDVAVLWPPSRAPIVMAVSFTQ -QQADAAARADVVASAARIAA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI00115BB202 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGLGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase class A n=1 Tax=Alloactinosynnema iranicum TaxID=1271860 RepID=A0A1G6XQ11_9PSEU -----HTALAELERKYSARLGVYAIDTATNTTI-THHPDDRFAFCSAFKALAAAAVLHRNP ---LSHLDTTVQYTRTDLMKHSPITARHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -ARLTDYARGLGDTVTRMDRTEPDITEATPGDPRDTSSPRAFGSTYHRILLGDALPTDKRD -FLRDLLDRGVAGADRIRAGVPKEWAVAHKSGTGDYGTLNDFAVVRPPNAAPLVVSIMSSK -ADRDADSDPALLAETAAYVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000B79F8F2 -----QAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPITESRVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSHAPIVMAVSFTQ -PEATAAARADVVASAARIAA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000E0A01F5 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TETSMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Q9X1Z2_ECOLX ---------KQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGI-------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SID5785 TaxID=2690309 RepID=UPI001361D4DA ---HLTAELGALEEQYAARLGVYAHDLGTGRTV-RYRAGERFPLCSVFKGIAAAAVLRDLD -HDGSELAKRVHYTQAEVDRYAPVTGEHVAGGLTVAELCAAAVGESDNAAANLLLRELGGP -TAVTRFCRSTGDRVTRLDRWEPELNSAEPWRRTDTTSPQAIGTTYGRLVAGRVLAPDDRA -RLTGWLVANTTNTERFRAGLPADWVLADKTGGGSYGVANDVGVVRPPGRAPIVLSVLSTT -HAAEGPSQSALVARAAGLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium attenuatum TaxID=2341086 RepID=UPI000F0398A1 ---DLQNRFAELEHRYAARLGVYVPATGTTSAI-AYRADERFAFCSTFKALLVAAVLYQYP ---LSHLDKVVTYTSTDIRSTSPITEQHAATGMSVGELCDAAIRYSDGTAANLLLAEVGGT -SGFTGYLRGLGDSVSRLDQQEPELNRDPPGDERDTTTAHAIALDYQQVVLGDALPPDKRA -MLTDWMARNTTGAHRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPAGVSHVVAIVSDR -ASYDAEWSEALVADAARCVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A103RPK5_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADASPRADVIAEAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1M2E7_MYCCH ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIRYAQSDLLEWAPVTSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium aquaticum TaxID=1927124 RepID=A0A1W9ZY20_9MYCO ----LDDQIAGLEKRNNALIGVFAANLDSDRTV-AHRADETFAVCSTFKGYAAGRVLQQVD -RGQLALDTRIFIDPNAIVANSPVTEERTGADMTIGELCQAAVQHSDNTAGNLLLKMIDGP -PGITAFARSIGDNRTRLDRWETALNSAIPGDPRDTSTPAALGAGYRAMLTADVLSPPQRQ -QLEDWMRGNET--SSLRAGLPAGWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAMMTRS -RADDPKA---------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3G4SNC1_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFTLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGR----------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075D61AE ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTMTDVAVLWPPSHAPLVIAASFTQ -PGADAPPRADVIAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium iranicum TaxID=912594 RepID=UPI000464F327 ----VEERIEALANRHNAQIGLYAVNLDSEESL-GYRDTEVFAMCSTFKAYAAAAVLQRAQ -QGRLALRDTVPIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRALGGP -PAITEFARSIGDDRSRLDRWEVELNSAIPGDPRDTSTPRALGAGYRAILTGDVLQPAGRQ -QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPSGQRMLLAFMTRS -AVPDAASLRPLIGELATLVMA-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=B5HBK2_STRE2 -----HDRLVELERKYDARLGMYALATGSGKVI-AHRADERFAFCSTFKGLAAAAVLDRNP ---LSHLDTLVRYTEADLLKNASITPRHVSTGMTIRGLCDAAVRHSDGTAGNLLLRDLGGP -AELTAYVRGLGDTVTRMDRIEPLITEATPGDPRDTTSPRAFGSDYREIVLGDALPPEKRA -FLRDLLERNATGAARVRAGVPKGWAVADKTGTGSYGTLNDIAVVWPPGSAPIVISIMSSK -ATEDAAYDQALIAEAAAYAV--- ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. Arc7-R13 TaxID=2500532 RepID=A0A3T0PX78_9RHOB ------EAARAVEAELGGRVGVALRRQGSPEGE-GYRAGERFPLSSTFKAPLCGAILTLVD -AGEDQLDRVIGYTSGDLVTHSPVTETR--DAMSVADLCEATLTLSDNTAANLLLERVGGP -EGFTDYLRAIGDETTRLDRWETDLNEGAPGDPRDSSTPEAMIATLERLLFGPVLSEPSQQ -QLEAWMRANAVADDLIRASLPEGWTIADRTGAGGYGSRSIVALIRTPQDEPWLAAVYLTG -NAADMASRNAAIARIGQAIVT-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9031 TaxID=2184566 RepID=A0A3P0NJV1_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAVLQAGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDVRDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGAR-GATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI00071674FB ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAVLQAGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDVRDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGAR-GATGIAAGVPPGWRIADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Salipaludibacillus neizhouensis TaxID=885475 RepID=A0A3A9KJF8_9BACI -----MEKFEQLEKEYDARLGVYAIDTGSKETV-EFCEDERFAYTSTSKALATAVLLKQNP ---ISVLKEIRTFTNEDIVTYSPITEDFVNKGMSLGKIAEAAMQYSDNTAGNLLFEELGGP -DGFEKALRESGDTITMVDRIEPDLNEAIPGDSRDTSTPKALATTLEVFGISEYLPTDKQE -IFTNWLKGNTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR -DEENASFNDELIAKATKVIAQAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EC2294 ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS -QAHDP-KAEN------------- ->[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. SO1 TaxID=1897061 RepID=A0A4Q7D7H4_9MICO ------AEFTSLEATYDARLGVYALDTGTGSEV-SWRDDERFAYASTIKAMAAAALLDTVG ---LAGLATPVPIEESDIVPYSPVTEPRVGGSMTLGEIAHAAMTVSDNTAANLMFEALDGP -AALDADLSGLGDDTTVVSRTEPDLNEAVPGDDRDTTTPRAFATNLNAYLFGEQLSGEEKA -QLETWLTGTQTGDTLVRADLPADWVVGDKSGSGGYGTRNDLALIRPPGRAPIIISVMSSK -AEPDAESDDKLIAEAAAAAM--- ->[subseq from] Beta-lactamase n=1 Tax=Endozoicomonas elysicola TaxID=305900 RepID=A0A081KB33_9GAMM --------ARDLENRHGGHIGIAVMDTSNQSLW-DYRGNTRFPLMSTFKTLACAKLLADAD -QKKQKLTTEAMITRESLVTYSPVTEPLTGQRITLEQACDATMTTSDNTAANLVLTGIGGP -QQLTDFLRSTGDTVTRLDRIEPELNEAKQGDLRDSTTPLAMADTLNQLILGNTLSDGSRA -QLKTWMMGNQVADNLLRSVLPEGWSIADRSGAGGHGSRGITAIIWSEKRLPLIISIYMTG -TNASFEERNQIIVKTGEAVFNHf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium septicum TaxID=98668 RepID=UPI00040E3028 ----VDDQIAELERRDNVLIGLYAANLDSGRIL-THRPDEMFAMCSTFKGYAAARVLQMVG -RRQISLDNRMFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMSRS -QADDADNLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Tardiphaga robiniae TaxID=943830 RepID=A0A163YVQ1_9BRAD ----APAALQAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID -RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP -AALTAFWNRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGDVLTSASRN -QLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG -GAPTAPQFETVFKAIGEMV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter sp. ND5 TaxID=1089784 RepID=G5CK56_9GAMM ---ETLVKVKDAEYQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNGAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRG--------------------- ------------------------ ->[subseq from] Beta-lactamase n=3 Tax=Comamonas TaxID=283 RepID=D0J7U6_COMT2 ---TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGITRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter junii TaxID=40215 RepID=A0A059WHE0_ACIJU --qQVEQDVXAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. MSMB1835 TaxID=1637876 RepID=A0A104C2B1_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGNGGFGTTTDVAVLWPPSRAPIVMAVSFTQ -PEAAAAARADVVATAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EBC185 ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLENRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGEALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nitratireductor aquibiodomus TaxID=204799 RepID=UPI000814125F ---TLSQTVERIESTLGARVGIMIRDTGSGWRW-SHRAEERFLMNSTVKALICGGVLAKAD -AGALALEDALPIRQFDIVSYSPVTQKQVGKAMSIADLCLATLDMSDNAAANLLIGRLGGP -KAVTAFLRSIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMTETWHALLLGDVLKPASRT -QLIEWMSHGGVTGALMRASLPKDWAISDKSGAGSH-TRNLVAMVTPPGRAPFLVSIFISD -TDVDFETRNGALKDVSAAIVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Burkholderia sp. CF099 TaxID=1882791 RepID=A0A658UPW4_9BURK ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERSLLDERVRYGDADLVANSPVTKRRTGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNVSVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNATGAARIRAAVPSGWLVADTTGSGDYGTANDVAVVYPPSAAPFVIAIYFTG -VTKQTPPRDEVVAEAARIVFD-- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI000DE29C10 --qSVEQEIKGMESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Bradyrhizobium TaxID=2631580 RepID=UPI00110D3A9D ------PALAAYERETGGRIGVHAENLSTGAKM-AWRAEERFVMCSTFKASLAAFVLARVD -HGADRLADLVAYGPKDLLEYAPVAKQNLAQGMSVSEMCKAIVELSDNTCANLLLARVGGP -AALTAFWRSTGDTISRLDHNEPELNRSPPGNPHDTTTPSAMAGNLRRFLLGAVLTPASRQ -LLTEWMVGCKTGNNRLRGGLPADWKVGDKTGNNGKDASGDIAIAWPKSGGPVLVCAYTQG -GSPAPQQLEAVFKEIGAMV---- ->[subseq from] Class A beta-lactamase n=2 Tax=Mycobacteroides TaxID=670516 RepID=A0A0R3FQ56_9MYCO ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIRYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A124L2B9_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycoplana dimorpha TaxID=28320 RepID=A0A2T5B5S1_MYCDI --------ARKAETGLRARVGLAVVDTASGKTW-LHNADQRFPLASTFKALACAALLD--- -AGADTLNKMAAIGQGELVSHSPVTKAMTGREVPAAGLCAITLRTSDNTAANKVLEVLGGP -AAVTAFLRSVGDDTTRLDRMEPELNEGRPGDPRDTTTPAAMAATLRKLVLGDALGEPERR -QLTDWLVANEVSGSLLRSGIPKDWRIADRSGAGGFGTRGIVAVMWPPHRKPIVAAIYLTE -TGVSMEARNAAIAEIGRAIAAEf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=A0A2S9NV33_9BURK ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDMVQQLLLGDTLREPQRA -QLTEWMSGGTRGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAVRIAT--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI000259B766 ------ADFAALEKASGGRLGVTVLNIGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadaceae bacterium SCN 69-123 TaxID=1660170 RepID=A0A1E4KZV2_9GAMM ------AGFAALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLAAAVLERAG -RGALSLDQRVPVRAADLLAHSPVSARHVGKDLGVRDLCRATLTTSDNAAANLLLPLVGGP -AGLTAFLRAQGDAVTLAARYEPDANRFAADDPRDTTSPAAMAGNLQRFVLGDALALAARR -QLADWLIDNETGDARLRAGLPPGWRVGDKTGSNGRDTSNDIAVLWPRGGTPWVLAAFLQG -STLDDAGRDGILRRVGERAAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI000992BE8E ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIRYAQSDLLEWAPVTSQHVTEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A2S8IHV7_BURCE ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCDAMLRSGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNKAVPDDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. Leaf111 TaxID=1736257 RepID=A0A0S9NZJ1_9RHIZ -----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE -AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAALGGP -AALTAYGRDLGDPVTRLDRTEPDLNAAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA -RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG -SDTTSEARDAAHAAIGRVIAATy ->[subseq from] class A beta-lactamase n=1 Tax=Jiangella muralis TaxID=702383 RepID=UPI00069D691C -----DPAVRELERAYDVTLGVSATNLATGARL-AHRPGDRFPILSVFKSIAAAAVLRDLD ---VSRLEHRVWYPPADIVPNSLITAEHVDTGMTVAELCDAAIRYSDNAAGNLLLRELGGP -RGLTAFARSIGDDATRLDRWEIELNSAEPGDVRDTSTPAALARTFAGLLVGDLLRSGDRR -RLRDWMLANTTSGPRFRDVLPDGWRLADKTGAGDYGSNNDAGVAWNPAGQPIVMVAMSRR -AERDAPRVDAALADVARLVVR-- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metoecus TaxID=1481663 RepID=UPI00130251E4 --qSVEQEIKGIKSSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGSGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia azotifigens TaxID=2057004 RepID=A0A5C6VUU6_9BURK ----AHERFGQLEASSGGRLGVAAVRTSDGAYV-SYRESERFPMCSTFKLLAVGALLKRSA -AERDLLDTRVRYGPADLVANSPITKQHAGEGMSVGELCAAALQYSDNTAANLLLNVIGGT -EVLNEFARSIGDTWFDLARREPDLNASVPGDMRDTTAPRAMMQDAQKLLLDDVLEAPQRE -RLKAWMLGNTTGAGRIRAAVRTGWPVADKTGSGDYGTANDVGVVYSPATA-YVLAIYFTG -VTKETPPQDAIVDEAARIVFD-- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI00115C2252 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TETSMAERNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C22D79 -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PSPTAPGDTPLIVKLATV----- ->[subseq from] Beta-lactamase n=2 Tax=Tistrella mobilis TaxID=171437 RepID=I3TTT5_TISMK ---RLADTVSRIEDQLDARIGLVLHDTGRGWRW-GHRADERFLMNSTVKMPICGAILAGVD -AGTVSLDETLPIRRADLVSHAPVTKPRVGTAMSIAGLCFATLDQSDNPAANLLITRLGGP -AAVTQFFRSIGDPVSRLDRLEPGLNSAPAGDPRDTTTPAAMAATMETLLLGTGLTPASRA -QLTEWMRHGGVTGALLRRSAPADWQIADKSGAGDT-TRNLVALITPPGRAPWIATIYLGD -AETDFATRNKALAEIGAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis str. Haarlem/NITR202 TaxID=1304279 RepID=R4M3D8_MYCTX ---DLADRFAELERRYDARLGVYVPATGTTAAI-EYRADERFAFCSTFKAPLVAXXXHQNP ---XXHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSDGTAANLLLADLGGP -AAFTGXLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGXPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EC63F6 ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETSAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDP-KAEN------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SCF1_KLEPN ------------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVV----- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter inhibens TaxID=221822 RepID=UPI000C9AE13F ---DLAETIRNWEQALDARLGVLLVHPATGWEI-AHNADDRFPLNSTFKPLLCAAILSQVD -RSTEDLTAQVEIRRKDLVSHSPVTERYIGTTRSLAQLCDAAITRSDNTAANLLLERIGGP -EGFTEYMQTSGDLITRLDRWETDLNSATPGDPRDTASPRSVLSTLHAALSGTMLSGSSSA -QLADWMQRDQLADDLIRAHLPERWTIGDKTGAGGHGSRGIIAFLRDPQGHEYLAAIYITE -TNADFSRRNQAISDIGRAMI--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZV2_9BACT -------------LQVDGGLGVSVLDTETGRAS-GWDETSTYPLNSTFKLLLAGAVLQRVD -RGQERLDRQIAVRSSDIVAWSPVAKEAVGGSMSLRSLCEAAMTRSDNAATNLLLRSVGGP -EALTATLRNMGDPVTRIDRYETEMNDVPPGDLRDSSTPSQMLKTMETLLLGDILSARSKE -QLAAWMIANTTGGARIRAGVPSGWTVGDRTGTGPRGETATIAAIYPPNRKPLLMTVYIRG -SSRNRDAQESTHAELARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium confluentis TaxID=28047 RepID=A0A1X1SH29_9MYCO -----DAALAALEQRYDALVGLFALDLDSGRSL-ARRDDDPFAMCSTFKTYAAGSVLQRAQ -RNELRLDQQVFVDPAELVANSPVTEANAGSSMTLAALCVAALQRSDNTAANLLLQTIGGP -PAITEFARSIGDNRSRLDRWETELNSALPGDPRDTSSPRALGGGYRALLTGDVLDETHRA -QLETWMRGNTTSEKSLRAGLPPGWTSADKTGAGDYGSTNAVGIAFAPDGRRLLLSVMTRS -RSPDAPWLQPLIAEVTALAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL440 TaxID=2675523 RepID=UPI0014227D83 ----IDDQIAELERRDNALIGLYAANLDSGQTL-THRPDEMFAMCSTFKGYAAARVLQLVG -RGQLSLDNLVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGVTAFARSIGDERTRLDRWEVELNTAIPGDPRDTSTPAALAGGYRAILAGDALGPPQRR -QLEDWMRANQT--SSLRPGLPDGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLALMTRS -QADD-PKADN------------- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000B4DBD84 ----VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQHVPASQLCAVTMRNSDNTAANGVLEMLGGP -QAVTSFLRTMGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVHTLQNLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVLWPPERAPLVAAVYITE -TKASMEERNAAIAAIGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000E16C42C ----VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQHVPASQLCAVTMRNSDNTAANGVLEMLGGP -EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVLWPPGRAPLVAAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum kholense TaxID=453584 RepID=A0A2T5UGC0_9RHOB ---ALTDTIARLETALPARIGVAIRDNGSDWGW-SHRDSERFLMASTFKSVLCGAVLDRAD -RGLLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLATLDMSDNTAANLLIDRLGGP -QEVTAFLRRIGDPVTRLDRTEPGLNLFDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA -RLADWMSHGSVTASLIRASTPPDWTVSDKSGGGRDYTRNLVAMIQAPGRAPVVVAIYLSD -CPADWATRNAAVAEIGAAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum subsp. acetamidolyticum TaxID=144550 RepID=A0A100WQU4_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRLDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=A0A1W0BGF4_9NOCA ---ELDIALAGIEERKHIRLGVIAHDPGRNLSY-IRRGEERFAMCSTFKVYAAAAILRLHT -QGRLTLDEPVPVAAADIVVNSPVTSAAQGRTLTLAQLCEASLTRSDNTAANLLLRRLGGP -AAVTGFARSLGDTATRLDRWEPELNSAEPGDPRDTTTPTGLADGYRELLLGSGLPAAAKQ -TLTDWMRASVTSGERIRAGLPAGWTAADKTGGGSYGTVNDAGVVWSPGGAPLLLVLLTSS -TTPDAPNDNAALAETTAAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0R0E0K1_9GAMM ------AGFAALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLAAAVLERAG -RGALSLDQRVPVRAADLLAHSPVTARHVGKDLGVRDLCRATLTTSDNAAANLLLPLVGGP -AGLTAFLRAQGDAVTLAARYEPDANRFAMDDPRDTTSPAAMAGNLQRFVLGDALALAGRR -QLADWLIDNETGDARLRAGLPPGWRVGDKTGSNGRDTSNDIAVLWPRGGTPWVLAAFLQG -STLDDAGRDGILRRVGERAAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=UPI000D0F6237 -----LRRLGRLEEQHGARLGVFGFDPATGRYV-GYREQERFPICSVFKTVLVAAVLRDLD -RNGEFLAERIHYTEQDVTRYAPITGRNRAHGMTVADLCAAAITHSDNTAANLLLRALGGP -HAVTRFCRSVGDPVTRLDRVEPDLNSAEPGRDTDTTSARAIAGTYARLTLGTALAPADRA -RLGGWLLANTTGGNRIRAGLPSDWSVADKTGTGAYGTTNDVAITRPPGRGPLVLAVLSTT -SDAHAPADEPLLAEAAALVAAH- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9017 TaxID=2184565 RepID=A0A3P0NZE5_9BURK ---AAQADLATLEKASNGRLGVAVLDTSNGTRI-AYHARERFPLCGTYAVSAAAAILARGA -LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCVALLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTTFRLDRWEPELNEAAPHDVRDTSTPVAMVDMMKRLLLGDTLGEPQRA -QLTEWLAGGTRGATGIAAGVPPGWRIADKTGSGGYGTTTDVAVVWPPSRAPIVMAISFTQ -PRADAAARADVVASAARIAS--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces scabiei TaxID=1930 RepID=C9YZ91_STRSW ------RRLGELEREYAARLGVFAHDTATGRTV-AYRAHERFPLCSVFKALAAGAVLRDLD -RDGAYLGRRIFYTKEYASAYSPITSENVAAGMTVGELCAATVSHSDNGAGNLLLRELGGP -TAITRFCRSLGDRATRLDRWEPELNTAEPWRITDTTTPRAIGGTYARLLLGRALPDADRE -LLTGWLIANSTNVERFRAGLPAGWTLADKTGGGSYGVANDVGVVWPPGRPPLVLSVLSTK -YDPAGPTDNALVARAAGLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Sporosarcina sp. ZBG7A TaxID=1582223 RepID=UPI00057B29D3 ---TMMKKFEQLEKEYDARLGVYAIDTGTKETA-EFREDERFAYTSTSKALATAILLKQNP ---IAVLEEIRTFTNEDIVAYSPITEDFVNEGMSLGKIAEAAIQFSDNTAGNLLFKELGGP -DGFEKALRESGDTVTMAERIEPDLNEAIPGDSRDTSTPKALATSLEVFGISEYLPADKRE -IFTNWLKGSTTGDSLIRAGVPEGWEVGDKSGAGGYGTRNDIAIVWPPNREPIIIAIMSSR -NEEDASFNDELIAKAATVIAQAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. UYPR1.413 TaxID=1080179 RepID=UPI00048A46C0 ----AHERFGQLEASSGGRLGVAAVRTSDGAYV-SYRESERFPMCSTFKLLAVGALLKRST -AERDLLDTRVRYGPADLVANSPITKQHAGEGMSVGELCAAALQYSDNTAANLLLNVIGGT -EVLNEFARSIGDTWFDLARREPDLNASVPGDMRDTTAPRAMMQDAQKLLLDDVLEAPQRE -RLKAWMLGNTTGAGRIRAAVRTGWPVADKTGSGDYGTANDVGVVYSPATA-YVLAIYFTG -VTKETPPQDAIVDEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=UPI00055A1291 ---DIAAQLRALEEQHTARVGVFGHHLGTRKTV-THRADELFPMCSLFKTLAAAAVLRDLD -QHGEVLYRVVHYTEADLVDGSDKTREHLADGMTIEQLADVAVRYSDNGAGNLLLRELGGP -TAITRFARSLGDPVTRLDRWETELNSAEPDRITDTTSPRAIGGLYGALVLGDALRRPDRD -RLTTWLLNNTTSGTRFRTGLPATWTIADKTGGGSYGTNNNAGVAWTESGDPVVLAVLTTK -PTPNATRDDPLIVDTAKLVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Ru73 TaxID=2080748 RepID=A0A2S4XQ97_9ACTN ---STTRQLRALEDKYAARLGVFARNMATGRTV-RHRADERFPMCSVFKGLAAAAVLRDLD -HDGEFLARRLHYTAAEVKKYAPVTGKNLARGMTVGDLCAAAVGESDNAAANLLLRELGGP -TAVTRFCRSAGDGITRLDRWEPELNSAEPWRRTDTTTPRAIGTTYARLVLGRALTPRDRE -RLTGWLVANTTNTKRFRAGLP-GWTLADKTGGGDYGVANDVGIGWPPHGAPLVLSVLSTT -YDPEGPTHDELVAETAELVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoaurantiacus M045 TaxID=996637 RepID=F3NSY9_9ACTN ----LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD -RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP -SAVTRFCRSLGDDTTRLDRWEPALNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE -RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVGNDVGVVWPPARPPLVLAILSTK -LDPAGPTENPLVAKAAAAIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacteroides TaxID=2618759 RepID=UPI0012DF7694 -------ALGALEKDFGGRLGVYAVDTGSNRQV-GLRADQRFIMCSTVKTFIVSAILHRRL -SQPGLLDKRIHYTQADILEWAPITSKHVAEGMTVAELCDATIRYSDNTGANLLIAQLGGP -KETEKYVRSLGDNVSRMDRLEEQLN--IPDRDLDTSTPMQLAANLRTLVLGDGLDPQGRD -LLTDWLKRNTTGDQSIRAGVPAGWTVGDKTGGGFKGESNDIAVIWPPGRAPIIVAALTIP -DDPKSTKGRPTIAEATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. ER1/6 TaxID=1891920 RepID=A0A1E5MGE6_9MICO ---ATTRAFAALEQQSDARLGVVVIDTADGSSI-GYRADERFAFASTNKAFIAAAVLDATS ---AAGLDEVVHYGRDDLLEYAPVTSRHVDEGMTVRALVDAAVRESDNTAANLLVDRLGGV -DGVSRWLLGIGDDVTRVDRVEPELNTAVPGDERDTTTPARSAADLRAVLVGDALDADDRA -LLLSSMAGTTTGDGTIRAGVPGGWSVADKTGTASYGVRNDIAVARPAGRDPIVLVVFTSH -DRAAAEPSDALVAAATRVALE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Siculibacillus lacustris TaxID=1549641 RepID=A0A4Q9VFE5_9RHIZ -------AVAAIEAKVGGRLGVAVRDSGDGRAF-GHRADERFASCSTGKLLLAAATLLRVD -RGEEDLARRIAYGRADLVPYSPVLEPGLAEGLGVEAIARAAVVLSDNGAANLLLAALGGP -AAMTAWARAFGDEVTRVDRGEPDLNSAEPGDPRDTTTPTAMLGHLDRLLLGAALSPASRA -RLFGWMVESPTGKRRLRGGIPADWTAGDKTGTGGHGTTADVALLQPPGRAPILVAAYLTE -CPAPIADREAALAAVGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=UPI00106F4ACF ---------TQEEQRLHARIGIAVLDTATNSIT-HYRGEERFPLNSTHKPLLCAALLREVD -RKVLALSASTQFEPSQLVEYSPITEKHVAPDMSWAQLCSAAVSYSDNTAANLIARKLNGP -QAVTQFLRDSGDTITRLDRYEPELNSAIPGDERDSTTPVVIAQTLNTLLLGNVLQPSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas sp. B1-1 TaxID=2710648 RepID=UPI0013DB30D6 -------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPIAEQDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDPVTRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGAGLLPPSRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ARVDEAQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium angelicum TaxID=470074 RepID=A0A1W9ZKN6_9MYCO ---DLTSRFMELEMKYTARLGVFVAATDPSAEI-AYRAGERFAFCSTFKAPLVGAVLHQYP ---LTHLDKVITYTSDDIRSISPVTQQHVQTGMTIRELCDAAIRYSDGTAANLLLAEIGGT -AAFTGYLRELGDNVSRLDQLEPELNRDAPDDPRDTTTPHAIALVFQQLILGDALPADKKT -MLTDWLARSTTGAKRIRAGFPAEWKVVDKTGTGDYGRANDVAVMWSPSGAAHVVAIYSDR -AGYDAEPSDAVIAEAAAAVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium/Ensifer group TaxID=227292 RepID=UPI00041B345A -----TAAAKSAETRLDARVGLAIYDTGGDRTW-FYNADERFPMASTFKALACAALLNAG- ---NEISNSTVTITEADVQSYAPVTKTMVGKRVSSAELCEITLRTSDNTAANKVLDVLGGP -PAVTSFLRSLGDRVTRLDRIEPELNEGSPGDPRDSTTPRAMADTIQKLILGNALEDRARI -QLTEWLVGNEVGGPLLRAGIPTDWKIADRTGAGGFGTRGIIAVMWPPARDPIVAAIYVAQ -TEASMEDRNEAIADIGRAIASLf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=A0A1Q5K4C4_9ACTN ----TTARLRELERLHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLEKVIHYTKADCVSDSPVTDTSIASGLSVARLCDAAICDSDNTAGNLLLRELGGP -QAVTRFARSLGDRVTRLDRWEPGLNTAEPGRVTDTTTPSALARDYARLVLGDVLERRDRA -LLTHWLLNCRTSDTRFRAGLPPEWTVADKTGGGSYGSCNDVGVAWTREGAPVVLAVLTSK -PASGAAGDHPLVRDVAKALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis sp. (strain ATCC 39116 / 75iv2) TaxID=385957 RepID=UPI000309E28E ------VDFADLEARFDARLGVYAIDTGTGREI-AHRADERFNYASAIKSLLAGAVLRRNV -----DLDKVVTYTDAEIQPNSPITKDR--RSVTVREAAEAALLQSDNTAANLLFAEVGGP -AGLAAVLREIGDTTTHPDRLEVELNSAIPGDVRDTSTPRAMAGSLRAFLLGEALPAGKRD -LLAGTMRRNKSGTELIRAGVPSEWPVADKTGTGDYGTRNDIGVIWPPNRAPIVLALMSSR -ATADASYDNKLLAEATSRVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1J1EE19_LYSEN ---ALGERLAKLEQRSGGRLGVAVLDTADGRRW-ATRGDERFAMCSTYKLPLVAAVLRKAE -LGEIDLHARIAVPPAALVPYSPATAPIARAGASVAQLCEASMTISDNTAANLLLPLVGDP -AGVNRFLHGIGDDISRMQRTPGAPLRA--GDANDTTTPNAMLATMRRLLLGDALNPASRQ -RLTEWMLASKTGDTRLRAGLPQRWRVGHKTGTGQ-GTANDIAIVWPGRRKPVLIASYLTD -AWGDDELRNAVLADVARTLAAHw ->[subseq from] Beta-lactamase n=1 Tax=Microbispora hainanensis TaxID=568844 RepID=A0A544YMQ3_9ACTN ---DVTAALRKLEASFKGRIGAYAIDTATGKTI-GYRSGERFPLLSTFKAVAAGAVLARTT --DRELTRKVVHWTAAEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -RGLTRYFRTLKDPVSRLDRWETDLNVWSPKERRDTTTPASVARDLRALTTGGALGAKDRS -RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVVWPAGNAPIIMAIYTNR -RAADGATADSVVARTATLLA--- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase KPC n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A4R8QZ10_9MYCO ----KSTELASLEKDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQADIVEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRLEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD -LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. PA05 TaxID=2604466 RepID=A0A5D0P2H2_9ACTN ---AVKKELRALEVAFKGRIGAYAIDTATGKTL-TYRAGERFPMLSTFKAPLCAAVLHLAR -RQPGLMSRRITWTAADMKPNSPVTEKHVKDGLTVSELCVAAVTQSDGTASNLLMKLIGGP -KGMTAFFRTLKDPVSRMDRWHPELNDWTPKDKRDTTTPAAMAADLRALATGTALHAKDRE -QLVAWLLASKVGAERIPAGLPGTWTIAHKTGTNSFGGGNDIAVIWPRKGAPIIMAVYTNR -TP-GLPTDNRTIARTATVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=A0A1W2CYV7_9PSEU ------DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTKYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD -FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGEHGTVNDIAVVWPPGREPVLIAIMSSK -SAADAKYDEALVAEAAAYVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=UPI00056D43C2 ---DLSHQFDQLERRYEGRLGVYVPE----PVI-AYRADERFAFCSTFKAPLAAAVLHQYP ---LDHLDKLVSYRRSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDSTAANLLLAEVGGP -AGFTTYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGAALPADKRA -LLVDWMTRNTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF -VGYDAQPNEGFVADAARIVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL B-24720 TaxID=1476876 RepID=UPI00068F6B41 ---RTARELRALEREHSARLGAYAHDTATGRTV-VYRPDERFPMCSLFKTIGAAAVLRDLD -RRGEFLARRIRYTAQYVEANSPITGRNLSRGMTVAELCAYSITHSDHTAANLLLRELGGP -GAVTRFCRSIGDPVTRLDRWEPELNSAEPWRGTDTTTPRAVGRTYARLVLGDALGPCDRR -LLTGWLLANTTSGERFRAGLPADWTVADKTAGGSYGGNNNAGIAWPPGRPPVVLAVMTTK -PDRDAPADDPLVARTAGVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. Gxj-6 TaxID=2614688 RepID=A0A5J5JXS6_9ACTN ---AVRKALRKLEASFRGRIGAYAIDTATGSTI-GYREGERFPLASTFKAFAAGAVLAGTT --EAELTRQVVHWTADELKPYSPDTGKHVDDGMTLAALCRAAVVHSDNTAGDMLLKRVGGP -KGLTRYFRSLGDAVSRLDRWEPELNVWSPKERRDTTTPLAIARDLRALTAGGALDAADRS -RLVGWLRGATTGGKRIRAGLPPKWIVGDKTGTGGYGTANDIAVVWPADAAPIILAIYTNR -LAAGGSADDEVVARTAAVLV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium flavescens TaxID=1776 RepID=A0A1E3RC76_MYCFV ----LESRLRDLEREHHALIGVFATNLDTGRTV-AHRAAESFAMCSTFKTYAAARVLQLVE -RGELSLDRRVRVDAADIVAHSPRTQPRVAGDMTVDELCQAAVQVSDNAAANLLLRTIGGP -PAITAFARSIGDQRSRLDRWELELNAAVPGDPRDTTSPEAIGGGYRALLTGTALAAPQRE -LLQRWMRANET--SSMRAGLPAGWTTADKTGSGDYASTNDVGVAYGPNGERLLLSLMIRT -AGADAPGLRPVIGQLAALLV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A109EIH9_9BURK ---TAHAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTL -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=UPI00087FB987 ----ARERFEQLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERSLLDERVRYGDADLVANSPVTKRHVGESMTIGELSAAALQHSDNTAAKLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVVAVYFTG -VMKQTLPRDEVVVEAARIVFD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QE32_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLGLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A4D4LT52_STRAX ---RLYGRLRELEREHSARLGVFARDMATGRTL-LYRADERFPVCSVFKTLAAAAVLRDLD -HDGEFLARRIRYTEQYVKDYGPVTGRNLAAGMTVAELCAAAVSDSDNAAGNLLLRELGGP -TAITGFCRSIGDGRTRLDRWEPDLNSAEPWRDTDTTSPRAIGKTYARLILGDVLPPQDRT -RLTNWLIANTTNTARFRAGLPADWILADKTGGGNYGVANDVGVVWPPNRSPIVMTVLTTK -HAAAGPSDSPLVARTAELLA--- ->[subseq from] Beta-lactamase n=1 Tax=Ruegeria conchae TaxID=981384 RepID=A0A497ZTK6_9RHOB ----LIQNTRLWEHRLDARIGVLLYETDAAWEV-SHRADELFPMSSTFKPLLCGAILAGVD -SGAVDLSENVAIQTSDLVEYSPVTSEHVETGMTIGALCQATMTISDNAAANLLLKQLGGP -AGLTEFLRATGDGTTRLDRWETALNEATPGDPRDTTTPRAILETIERLLFDEVLSPASAA -QLGQWMIDDQVADGLIRAHLPNSWIIGDKTGAGGYGSRAIIAFLQTPEPRTYMAAIYLTE -SDASFPERNAVLSDIGQAMI--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000893B2C4 --qSVEQEIKGIESSLSTRIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F58A092 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSDSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=A0A252APJ1_9PROT --------IAAYEKATGGRIGVYACNLATRQRL-TWRENDRFALCSTFKVSLVALVLQRVE -QGKGRLDEAVSYTKADIERYAPVAQASLEAGMSVRALCQAAIEQSDNACANLLLARVGGP -ENLTRFWRSLGDQATRLDDWEPDLNRVPPGSVRNTTTPAAMAGVLEHLLFGEVLSASSRL -LLTEWLKGCQTGRNRLRAGFPAGWEVGDKTGTNGQDAAGDCAVAWPSPRTPLIVCVYTRG -GHPAEDQFRAAFAGIARLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Beijerinckia sp. L45 TaxID=1641855 RepID=UPI00131C5855 --------LAAYELVSGGRIGLYAGNIRTGAKI-LWRADERFVMCSTFKASLAAFVLARID -QGKDRLYAMIAYGPGDLMDYAPVAKRNLAAGMSVVAMAEAAVTLSDNTCANLLLARVGGP -AALTRFWREIGDDTSRLDHNEPALNRSPPGDPHDTTTPGAMAGTLRRLVLGDALSAESCA -RLTGWMVACTTGANRLRGGLPKDWRIGDKTGNNGKDASGDIAIVWPKTDTPIVICAYTQG -GAPTAPALEAVFADIGRLVAQ-- ->[subseq from] Beta-lactamase Toho-2 n=1 Tax=Escherichia coli TaxID=562 RepID=BLT2_ECOLX ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTARAGADVASLRWVMRWAKPS--G -AVGDVAQRQYDRAAGIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium wolinskyi TaxID=59750 RepID=A0A132PIK8_9MYCO -----DDQIGELERRHNAVIGIYAVNLDSNRIV-SHRADDMFAMCSTFKAYAAGRVLQMVG -RDQLSLDNRVFVDPDAIVMNSPVTEPRAGSEMTLGELCAAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRALLVGDALSPPQRR -QLEDWMRANQT--SSMRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPAGQRLLLAMMTRS -QTDDPKAANPLIGELT------- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=A0A1H2KCA7_9ACTN -----DPAVRELERTHDVTLGVSATNLATGARL-AHRAGDRFPILSVFKSIAAAAVLRDLD ---EARLDHRVWFPPADILANSPITAEHVDTGITVAELCDAAIRFSDNAAGNLLLREIGGP -RGLTAFARSIGDGATRLDRWELELNSAEPGDEQDTSTPAALARTFAGLLVGDLLRPADRR -RLRSWMLANTTSGPRFRDALPDGWRLADKTGAGDYGTNNDAGVAWNPAGEPIVIVAMSRR -TERDSVRVDAALADVARLVVR-- ->[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4R8IWY2_9MYCO -------ALAELERRFGARLGVYGVATDTGATV-AYRADERFAFCSTFKALAAGAVLHRHS ---VAHLDTRVGYTEHDLMKSSVITRRHVATGMTIGELCDAAVRFSDGTAGNLLLRVLGGP -EQLTAYARSLGDTVTRMDRVEPHVADAVPGDVRDTSSPRALTEDIRALLVGDALGPAERA -VLQDLMQRNATGMERIRAGLPPDWTVADKTGTGDFGTLNDIAVVWPPHRAPLAMGIMSTK -TSKDAAYDPALLAEAARYVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia suismassiliense TaxID=2077092 RepID=UPI000D1F84FF ---------VELEQQFGARLGIYALSTGTNRTL-THRADERFAFCSTFKALAAAAVLHHNP ---LTHLYKPVTVTKADIRSISPVTERRVDTAMTIGELCDAAVRFSDGTAGNLLLDDIGGP -AGLTDYLRGLGDTVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQHLILGSALPEDKRA -ILTDWLVRNVTGAKRIAAAAPAGWTIADKTGTGNYGRANDIAIVWPTAHPPLVLAIMSDR -TGYDAEPSSELIAEAARHIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium syngnathidarum TaxID=1908205 RepID=UPI00095E9D0B -----DDGIAELERRNNAFVGLYASNLDSGRTL-THRADEMFAMCSTFKAYAAARVLQMAE -HGEVSLDNRVFIDREAIVPNSPVTETRAGGEMALAQLCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPSALAVGYRAVLAGDALSPPRRR -LLEDWMRANQT--SSMRSGLPEGWTTADKTGSGDYGSTNDAGIAFGPEGQRLLLVMMTRS -QA-DDPKAEPLIGELTA------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium aurum TaxID=1791 RepID=UPI000B35AFC0 ----WEEQVRELEARYNAFIGVYAANLDSGVTL-ENRADETFALCSTFKAYAAAAVLQRVA -AGELSLEQRVFVDPAALLPNSPVTGEHAGAEMTLAELSQAALQRSDNLAANLLLETLGGP -SAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTGTPRALAAGYRNLLVGQALPAEQRE -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYGTTNDAGVAYGPDGTRLLLTIMTRT -QSADAEGLRPLIGEVAAAAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=[Pseudomonas] mesoacidophila TaxID=265293 RepID=A0A2A4FIX2_9BURK ---AAQSQLDALEQASNGRLGVAALDTASGARI-AHRSRERFPLCGTFAVVAAAALLVRGA -LDASLLPRRILYRRYELVPGSPVTERYADTGMTIGQLCEAMLHSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPGDERDTSTPLAMAETMRRLLLGDALGEPERA -QLTRWLTGSANGVKGIRAGVPSDWRVAGKAGTGGYGTTSDVAVLWPPSHAPLVIAVSFTQ -PAADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiales TaxID=80840 RepID=D2K8A5_9BURK --qQVEQDVKAIEVSLSTRIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas smyrnensis TaxID=720605 RepID=UPI0002E33B45 ---DLERQLGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTGKCFIAAAVLARVD -EGRETLDRRIVIEEGDLVGWTPVTEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPALNTDHPGDERDTTTPLAMMATLRTLLLGDALSPSSRH -QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTFM -PNATGAERDETIAAVGRLAA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Cryptosporangium aurantiacum TaxID=134849 RepID=A0A1M7TYS9_9ACTN -------DLTALETSLGTLIGAWALDTGNGVTV-SHRADERFGLNSTFKVLAAAAVAQRGG ------LDRVVRWTRADLVAHSPITEQHVDDGLPLEQVCAASVTHSDNAAGNLLLKELGGP -GGVTRFVRTLGDDATRLDRWEPALNAFTPGDPQDTTTPAAIGRTLQRLVLGDGLDGTARA -LVTSWLRANTTGNLRIRAGLPSDWTVGDKTGTGDYGAANDIAVAWPPSGAPIVYAIYTRR -PTEDEERDESVVARTATILT--- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax temperans TaxID=80878 RepID=A0A543L1K6_9BURK ---TWNSAMEGIEHNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD -QGRENLNARVHYAPADVVEYSPVSAPRAGPGLTVGELCSATVSLSDNTAANVLLERHGGP -AALTRYLRMLGDPITRLDRNEPTLNEAAIGDVRDTTTPRAMLQTMQKLVLGESLSASSRA -WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVTCYLTR -SAVAPEQRDAAIAAVGRAVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax temperans TaxID=80878 RepID=A0A0D7KD85_9BURK ---TWNSAMEGIEHNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD -QGREKLDARVHYAPADVVEYSPVSGPRAGTGLTVGELCSATVSLSDNTAANVLLERHGGP -AALTRYLRALGDSITRLDRNEPTLNEAAIGDVRDTTTPLAMLQTMQKLVLGESLSASSRA -WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVSCYLTR -SAVAPEQRDAAIAAVGRSVVS-- ->[subseq from] Beta-lactamase n=1 Tax=alpha proteobacterium U9-1i TaxID=1605283 RepID=A0A1V1PML8_9PROT -------RIAAIEARLGARIGVAALNTASAAWI-GHRIQERFAMASTFKWLLAAQMLQMAE -QMPEFLQQRILYDEADLLDYAPTARAHLARGMTVEECCEAIVVVSDNTAANLLLVGASGP -AGFTSFIRANADSVTRLDRTEPALNENALGDERDTTTPDGMARSLRNVLVGEVLNPASRE -KLIGWMVASTTGLQRLRAGLPSDWRVGDKTGSGARGAVNDVAIAWPPGRAPIVIASYMSD -GEADTATRSAAHAEIGRIIAETw ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium peregrinum TaxID=43304 RepID=A0A1X2BCH1_MYCPR ----VDDQIAELERRDNALIGLSATNLDSGRTL-THRPDEMFAMCSTFKGYAAARVLQMAG -RKQISLDNRVFVDPGAIVPNSPITETHAGSEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYHQILAGDALSPPQRR -QLDDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDPKADNPLIGELT------- ->[subseq from] Uncharacterized protein n=1 Tax=Halomonas huangheensis TaxID=1178482 RepID=W1NBR6_9GAMM ---DLGAEFEALEQRHSGRLGIALMNLSSGVVA-SHRGDERVLFNSTIKTVIAAAMLSRVD -RGEISLDSRLVVSESDLGGWTPITEQHLGEPMTVAELCQAAVAWSDNAAANVLVTDAGGP -AAITEYLRSIGDEVTHLDRMEPELNEDHEGDERDTTTPLAMLQTLRTLIFGDTLSPQSRH -QLVAWMVEGKTGDNRLRAGMPPNWLVGEKTGTNSVGNANDAGVAWPMDRGAVIAVAYTWL -PDAEPEQRDEVIAEIGKLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces griseoaurantiacus TaxID=68213 RepID=UPI000997E7D7 ----LARRFRALEKEYAARLGVYAHDTATGRTV-RYRADETFPLCSVFKALAAGAVLRDLD -RDGEFLAKRVHYTQKQADDYAPVTGENVAGGLTVGELCAAAVSESDNCAGNLLLSELGGP -SAVTRFCRSLGDDTTRLDRWEPALNSAEPWRKTDLTTPQAIGRTYGRLLLGRALPEADRE -RLTGWLVANTTNTERFRAGLPKDWILADKTGGGSYGVGNDVGVVWPPARPPLVLAILSTK -LDPAGPTENPLVAKAAAAIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonadaceae bacterium SI-3 TaxID=2079806 RepID=A0A3T0SG48_9GAMM ---ALRETVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD -RDEIKLDTRVRFDETDLQSYSPITKDRVGRSMSLFDLCSATTSMSDNTAANLILRNTGGP -QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE -QLKAWLINNKVGGPLLRASLPESWKIADRTGSGGYGSRGVIAVIWPQGSEPVIVAVYLTG -TTLTLEERDAAIAEVGAALV--- ->[subseq from] Beta-lactamase n=1 Tax=Tardiphaga sp. YR296 TaxID=2135488 RepID=A0A420AKL9_9BRAD ----APAALQAYERDTGGRIGVYAENLKTGAKI-AWRAHERFVMCSTFKASLAACVLARID -RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP -AALTAFWTKTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNVKRFVTGNVLTPTSRD -QLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG -GTPTAPQLETVFTGIGEMV---- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=A0A508X6R1_9RHIZ ---DVTERLRQLEERTGGRLGVAVLDMETNISF-GYRETERFAMCSTFKALAAACALARVD -RGEEKLDRRITFGKEVLLPHSPVTEKHVGGNMTIAELCEAAITISDNAAGNLLLESFGGP -QGLTSWLRSIGDNTTRLDRTEPDLNEARKGDPRDTTTPAAMLDTLGKLALGSVLSENGRG -QLVDWLVANETGDARLRAGLPKDWRIGDKTGTSSTGA----------------------- ------------------------ ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=UPI000408A35D ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGEVLHEPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVTAAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML171202 TaxID=2480817 RepID=A0A4Q8LLI6_9GAMM ------RDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAD -AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAVVTNSDNTAANLLLARTGGP -PALTAFLRKQGDAVTRSDRYEPEMNNFAPDDPRDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDACLRAGLGKRWRVGDRTGSNGRDTRNDLAVLWPLGGTPWVLVALLQG -ARVDADQRDAVLARVGALA---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=UPI00075F025C ----AQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP -QAVTSFAHESGDTTFRLDRWEPELNRAAPGDERDTSTPLAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAAVPPGWRIADKAGSGGHGTTTDVAVLWPPSRAPIVLAVSFTQ -PAADAAARADVVASAARIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium brachiatum TaxID=269660 RepID=A0A1I3N5K7_9RHIZ --eAVESALAAIEKRLGGRLGVSAGT-PERVFL-RHRADELFPMCSTFKVLAAACVLVRVD -AGTESLDRLVTYGNDVLLSYAPVIRKGLEAGMTVADLCAAALEWSDNSAANLLLAALGGP -EALTLWLRGIGDTVTRLDRNEPTLNTALQGDPRDTTSPEAMRATLARLLLGPSLSAASRA -RLEAWMVASQTGFKRLRAGLPPDWTAGDKTGTGDHGTVNDVAILRPPGRAPILACVYVTG -AQAPTEVVEVAHAEIGRLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0009F34319 ----VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQHVPASQLCAITMRNSDNTAANGVLEMLGGP -EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVAAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=UPI0007B53846 ---DVRGRFAELEHRYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDTVVTYTGADIRSTSPITQQHVATGMSVGELCDAAIRYSDGTAANLLLADIGGT -SAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTARAIALDYQQLVLGDALPVDKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGVPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=UPI0011159EF2 ---ELDIALAGIEERKHIRLGVIAHDPGRNLSY-IRRGEERFAMCSTFKVYAAAAILRLHT -QGRLTLDEPVPVAAADIVVNSPVTSAAQGRTLTLAQLCEASLTRSDNTAANLLLRRLGGP -AAVTGFARSLGDTATRLDRWEPELNSAEPGDPRDTTTPTGLADGYRELLLGSGLPAAAKQ -TLTDWMRASVTSGERIRAGLPAGWTAADKTGGGSYGTVNDAGVVWSPGGAPLLLVLLTSS -TTPDAPNDNAALAETTAAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P9-22 TaxID=2024613 RepID=A0A5A7ZHD5_9MYCO ---TLEDQIRELEARHNAFVGLYAANLQSGFTV-EHRADEAFALCSTFKTYAAARVLRGVA -DGELTLDQQVFVKPEGLLPNSPVTGERLGQQMTLAELSQAALQRSDNLAANLLLETIGGP -QAITAFARSVGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGYRNLLAGDALPPAQRE -LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGIAYGPDGARVLLTIMTRT -QTADAEGLRPLIGEVAALVL--- ->[subseq from] Beta-lactamase n=1 Tax=[Mycobacterium] stephanolepidis TaxID=1520670 RepID=A0A1Z4EYY3_9MYCO ------SELASLEKDFGGRVGVFALDTGSGATL-GHRANERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--IPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWSTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0F7NE15_9ACTN --qRATREFKDLERAHDARLGVYAVDTMTGQEV-AYREGERFAFASTVKAFEAGAVLRKRK ---LAGLKKEITYDRSDLVANSPITEKHVDDGMTLGELCDAAVRYSDNAAANLLFEEIGGP -RALQSFLRETGDDTSRMERIEPALSDWEPDAVRDTSTPRALAGNLRAFVLGDVLDAPERA -RLAEWLRTNTTGDASIRAGVPKDWKVGDKTGTAAFGGRNDIAVVWRPDAAPLVVAVLSHG -TDRDAEPDDELIAKAAAVVSD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 4121.5 TaxID=1938847 RepID=A0A2N0EMU9_9ACTN ---DLGDALAALEREHGARLGVFAHDTGSGATV-RHRADELFPLCSTFKTLAVAALMHAGD -----DLAARVHYTDQDVADYAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP -SAVTRFCRSIGDRVTRLDRWEPALNSAEPGRVTDTTSPRALARSYARLTLGDTLAPAHRA -RLTAWLRATTTGANRLRAGLPAAWALADKTGTGSYGTANDAGLARPPHRAPIVLTVLTTK -PTPDAAPDEPLIARTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. ER1A TaxID=1517681 RepID=A0A084TBK1_9VIBR ---TLDESIASIEQRISGRIGVSVLDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDVD -SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP -QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNQGSKN -QLIAWMQGNTVSDSLLRSILPKGWSIADRSGAGANGSRGFTGAIWADNHKPMIISIYLTQ -TDLSMSERNQIINEIGGLIFETy ->[subseq from] class A beta-lactamase n=1 Tax=Achromobacter agilis TaxID=1353888 RepID=UPI001011C27E ---AFDQALAELEASSQGRLGVGLLDTASGQVA-GYRGDERFLMLSSFKTLAAAYILARAD -RGEDQLTRRIPITEADLQEHAPVTRRHVGPQMTLAELCEATVTTSDNTAANLMHRSYGGP -QALTRYLRSLGDIVTRHDRYEPELNRPHAGEPLDTTSPHAMSATLNALLFGQALKPQSRQ -LLQSWLLASITGGKRLRAGFPADWKVGEKTGTYSKVGANDAGFAQAPGGAPIIVCVYLET -TAIPMDERDRIIAEVGKRVA--- ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis benevestitus DSM 16100 = ATCC BAA-896 TaxID=1121022 RepID=V4PFB9_9CAUL -----AQRMIEIQKRHGGRVGVSALNSEANGSL-SIQSTELFAMCSTFKWVLAAAILQQVD -QGKLKLAQTVKYGPKDLLDYAQVTKMHVAKGMTIGDLCSAAVALSDNTAANLLLPLVGGP -AGLTAFVRGLGDSITRFDRNEPSLNTNIDGDERDTTTPEAMSNLLRTVFTGPLLKPESLK -PLKDWMVATTTGRGRIPSGLPAGAVLGHKTGSGANNATNDVGVIWLPGKDPVFLSIYTTG -GTLDDAGRDQVIADITRLVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Achromobacter agilis TaxID=1353888 RepID=A0A446CD07_9BURK ---AFDQALAELEASSQGRLGVGLLDTASGQVA-GYRGDERFLMLSSFKTLAAAYILARAD -RGEDQLTRRIPITEADLQEHAPVTRRHVGPQMTLAELCEATVTTSDNTAANLMHRSYGGP -QALTRYLRSLGDIVTRHDRYEPELNRPHAGEPLDTTSPHAMSATLNALLFGQALKPQSRQ -LLQSWLLASITGGKRLRAGFPADWKVGEKTGTYSKVGANDAGFAQAPGGAPIIVCVYLET -TAIPMDERDRIIAEVGKRVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004C91006 -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] Beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=BLAC_STRCE -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora terrae TaxID=155974 RepID=UPI000B8031F1 ----LAREFAQLERKYDARRGVYAVDTKRDRTV-SYQADERFAYASTSKAFAAALVLDATT ---PQQLEEPVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRSLGGP -AGLQA---GLGDQVTSADRYEPDLSSAIPGDPRDTSTPRTMATNLRKFTVDTALPEEDRA -MLDDWLRNNTTGTDVIRAGVPRDWVVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR -DKEGAERLDALVADTARIVA--- ->[subseq from] Beta-lactamase n=2 Tax=Leifsonia sp. Leaf336 TaxID=1736341 RepID=A0A0Q5LPL0_9MICO ---AAQRQFAALEAEHDARVGVYAVDTGTGAHI-AYRADERFGYASTYKALAAAAVLADPP ---AGGLDSPVGYTSDELVAYSPITEQHTSTGMTLRELADAAVRYSDNTAGNLLLTALGGP -AGFQEALRELGDTVTRPERAEPALNELTPGGTDDTSTPRALATDLREYALGSALPADARA -QLKTWLVGNTTGDALVRSVAASGWTVGDKTGSADHGTRNDIAIIWRDAGTPIVIAVLTDH -TAVDADTDDALVASAAEAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella enterica subsp. enterica serovar Albany TaxID=211968 RepID=Q2QCK1_SALET --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHPAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Paracoccus sp. PAMC 22219 TaxID=1569209 RepID=UPI0005A5F17B ------EAARAVETELGGRVGVALRRQGSPEGQ-GYRADERFPLSSTFKAPLCGAILTLVD -AGEDQLDRVIGYTSGDLVTYSPVTETR--DAMSVAELCEATLTLSDNTAANLLLDSVGGP -KGFTDYLRAIGDETTSLDRWETDLNEGAPGDPRDSSTPEAMIATLEKMLFGPVLSEHSQQ -QLEAWMRANAVADDLIRASLPQGWIIADRTGAGGHGSRSIVALIRTPQDEPWLAAVYLTG -NEADMANRNAAIARIGQAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas sp. ZOR0011 TaxID=1339230 RepID=UPI000647D798 ---ALSAQMKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSASRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiales TaxID=80840 RepID=A0A1E3YU33_9BURK ---EWNETLASIERTAQGRLGVAMLDTGSGLQL-GWRQDERFAMVSTFKAVLAGWMLALVD -QGKERLDARVHV-----VAYSPVSGPRAGDGLTVGELCSATVSLSDNTAANLLLARHGGP -AGFTAFVQSLGDSITRLDRTEPTLNEAKVGDPRDTTTPLAMLQTLQKLVLGDVLTPPSRA -WLQRWLVETSTGDKRLRAGVP-GWKVGDKTGTADSGTANDVAVMWPPGGAPVLVTCYLTR -STVKPEQRDAAIAQVARAVAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. or43 TaxID=2478957 RepID=A0A652LRT0_9ACTN -----LARLRELERVHGARVGAFAYNVATGAFV-RHRADERFPVLSTFKTLAAAAVLRDLD -RDGEVLGRLVRYTKEDCVPDSRITDTCLASGLTIERLCEAAVCDSDNTAANLLLRELGGP -RAVTRFSRSIGDPVTRLDRWEPDLNSAEPGRRTDTTTPAAIARDYARLVLGDALEARDRQ -RLTGWLLNCRTSGTRFRAGLPPEWTVADKTGGGSYGSCNDVGIAWTPDGTPVVLAVLTTK -PDGDAAGDHPLVARAAEALA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI00102D70E0 ------RDFAALEQVSGGRLGVTLLEVGTGRRL-GRRQDERFPMCSTFKALLAAHVLSLAD -AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP -PALTAFLRKQGDAVTRSDRYEPAMNDFALDDPRDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG -ARVDADQRDAVLARVGALA---- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. V23 TaxID=2044878 RepID=A0A2S4LMT0_9RHIZ -----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGTFPLCSTFKLPLAAAILARVE -AGRERLARRLAYGEADLDTYAPVTTHALRAGMSVEALCAAALVWSDNTAANLLLGALGGP -AALTDFCRDLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLSEAGRA -RLEGWMTASRTGTKRLRAGLPADWGIGDKTGSGAYGTANVVALLRPPARAPLVAAVYITG -SDATSEARDAAHAAIGRVIATAy ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea sp. NEAU-D13 TaxID=2714351 RepID=UPI0013FBE47E ------DALVELEKKFDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MTHLDTVVTYTEADLMKSSTITRQHVQTGMKLRDLCDAAVRHSDGTAGNLLLRALGGP -AELTRYLRDLGDDETRMDRVEPDITSATPGDPRDTATPRSLGTDYQRLVLGDALEPAKRD -FLKDLLERSVTGAKRIRAGVPQGSKVASKTGTGSYGTANDIAVVWPPGREPILIAIMSSR -SSADAKYDEALIAEATAYVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NEAU-LD23 TaxID=2486417 RepID=A0A3M8T018_9ACTN ---EITRQLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPICSVFKALAAAAVLRDLD -RDGEFLAKRVHYTQEFVRKYAPVTGKNIEGGLTVEQLCAAAVSESDNAAANLLLSDLGGP -TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRE -RLTGWLVANTTNTERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK -YDPQGPTDNPLVARAAALVAD-- ->[subseq from] FRI family carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001231866C ------EEVRELETSFGGRIGVYILNPKNGKEF-AYRQDERFPLCSSFKAFLAASVLKRTQ -EKSVSLDDMVEYSGRVMEKHSPVSEKYRKTGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNTAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS -LLQEWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDVAILWTDANSPAVMAVYTTR -PNQNDKHDEAVIKNAAKIAIK-- ->[subseq from] Beta-lactamase CARB-6 n=1 Tax=Vibrio cholerae TaxID=666 RepID=BLC6_VIBCL --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKTIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F57B07 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGACL-------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B5KFC7_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAVVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D75018C ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERA------------------------ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-1742 TaxID=1772285 RepID=A0A101ALI7_9MYCO --------VEALERANNAVIGVFAVDLDTGRTV-AHRAQESFAMCSTFKAYLAAQVLQLVG -RGERSLDQTLPVTAADVQPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRNVGGP -PAVTAFARGIGDPRSRLDRYEIELNAAVPGDPRDTSTPEALAGGFRAILTGDALAPPQRR -LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTKT -ATPDAENMRPLVGEVTAAV---- ->[subseq from] Beta-lactamase Toho-1 n=2 Tax=Legionella lansingensis TaxID=45067 RepID=A0A0W0VF14_9GAMM ----IDKKLAELEASFGGRIGVYAINTANNTHL-QYRANERFPMGCTSKVIGVAAILKKSM -NDRTLLSQKVTYTKSDLTNWNPITEKHLADGMTVAELCAAAIRYSDNTAMNLLVRILGGV -EGMNAFARSIRDHSFRQDHWPTEAMSGGQGDLHDSSTPSAMANSLKRLALTNTLAKPQRE -LLLSWLKTNTTGDNRIRAGVPKGWTVGDKTGTGYYGTTNDIGIIWPPKCAPIVVAIYYTS -NDKKAVKREDIVAATIRILINEf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio mediterranei TaxID=689 RepID=A0A3G4VEP8_9VIBR ---TLDESIASIEQRISGRIGVSVLDSRNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD -SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP -QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNQGSKN -QLMAWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGFTGAIWADNRKPLVISIYLTQ -TDLSMSERNQIINEIGGLIFQTy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A1A3AQV4_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRTI-RHRPDEMFAMCSTFKGYAAARVLQMAE -RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKAIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS -QGPKAENLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=UPI00138A3AE6 ---TLADTVERVENRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD -AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIAHLGGP -QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPAAMTETLRGLLLGDVLSRSSRG -QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD -VDADSQTRNRALQDVGRAAM--- ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis excentricus TaxID=78587 RepID=A0A3G9G883_9CAUL -----GQRLMEIQKRHGGRVGVSVRDTAADGSL-NINSSQRFALCSTFKWVLAAAILKAVD -ENKLTVAQEIRYGKADLLDHSPVTEKHVAKGMTVGDLCSAAVAVSDNAAANLLLPLIGGP -AGLTAFVRGLGDTVTRLDRNEPELNSNIEGDERDTTTPDAMSSLLRTVFTGAVLQPQSLS -LLRDWMVATVTGPDMIPAGVPKGWTVGHKTGRGANGAVNDVAVIWPSDKPPLFLSIYTTG -GTLDDTGRNQIVSDITRLVID-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164PKR9_9NOCA ------ASLAELERRYGARLGVFAVATGTGATL-AYRADDRFAMCSTFKGLAAAAVLSRNP ---LSHLDTRVSFTRDEIRSISPVTERHVDTGMTIGQLCDAAIRYSDGTAGNLLLDDIGGP -AALTAYLRTLGDPWSPMDNYEPELNRDAPGDERDTSTPRALATDYRTLVLGTALSPEKRG -LLTDWLLRSTTGTGRIRGAVPGSWQVAHKTGTGDYGRANDVAIIYPPSTPPLVLAIMSDI -SNYNAQPSDQLIAEAAT------ ->[subseq from] class A beta-lactamase n=1 Tax=Paenalcaligenes suwonensis TaxID=1202713 RepID=UPI0014075821 ------QKAAAIEEQLQARVGVAVVDTGSGQSW-LYRADERFPMASTAKTLVCAALLQQGE ----PLLHSPILLQPDDIQTYAPVTKELVGQTLSAFQLCEITLRSSDNTAVNVVLKVLGGP -TAVTSFLRTIGDQSTRLDRMEPEVNEATPGDERDTTTPSAMAATMRALLLGSALNPTERE -QLVGWMKANEVAGPLLRAGVPSDWLVADRSGSAEYGTRGVAAVLWPAQHAPLVVAVYITE -TEAPIEARNAAIASLGQAIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium malmesburyense TaxID=1566886 RepID=UPI000B1A52A0 ----VADRLEAMERSQNALIGVFAVNLHTGRTV-AHRAQEPFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEEGDIVPNSPVTGAHVGQTMTLAELCQAALQQSDNAAGNWLLRTIGGP -SGVTGFARSIGDQRSRLDRWEVELNAAVPGDPRDTTTPEAIGGGYRSILTGNVLGEPQRR -RLEEWMRANQT--SSVRPVLPPGWTIADKTGSGDYASTNDVGIAFGPAGERLLLTIMTRT -PTPNAPNNRQLVGEVGSMLVA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus maanshanensis TaxID=183556 RepID=A0A1H7TPN0_9NOCA --qSLDATLDALEARYSTRIGVTAIDPASGRTY-RHRGEERFALCSTFKTYAAAEVLRRTV -TGASSLEEPVMVDPGDLVENSPVTEAAAGTAMTLRQLAEAALTRSDNTAGNYLLEEIGGP -PAVTALARDIGDESTRLDRWEPELNTALRGDPRDTSTPNGLAEGYRALIVGDALGSAERA -QLGDWMRASKTSDKRIRAELRPGWTAATKSGAGSFGTVNDAGVVWDPDGNPLVLAILTDS -LTADAQGNNQAVADTAAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5P4A0_9BACT ---DFANRILSIEKRIGARIGVAALDTGSSKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD -GGQEKLDRFVSYGAKDILEYAPVTKAHLKDGMPLGALCAAAIEQSDNTAGNLLLDTIGGP -VGLTNFARSLGDQMTRLDRKEPELNGAIPGDERDTTTPASMQADLVRLLIGDALSQSSRH -QLEEWLQGNTTGASMIRAGVPPKWTVGDKTGRCGKGPTNDVGILRPPGRQRL-------- ------------------------ ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio metschnikovii TaxID=28172 RepID=UPI0012AE7B19 ---RVEQEVRSIEEQLSARIGVAVFNTETGEHW-NYRGEERFPLTSTFKTIACAKLLHDSE -QGDIDPLSKVKIEENDLVTYSPIIEQYVGQEITLDDACQATMSTSDNTAANMIIKAVGGT -ESITSFIRAMGDEVTRLDRIEPDLNQGLVNDLRDTTTPNAMVITLHELLFGSVLSESSQQ -KLLTWMINNQVTDNLLRSVLPNGWGIGDRSGAGGFGARSITAIVWSKTQSPIIISIYIAQ -TEVSIEQRNQAIVKIGKAIFDNy ->[subseq from] Beta-lactamase class A n=1 Tax=Frondihabitans sp. PhB153 TaxID=2485191 RepID=A0A3N4V2L9_9MICO ---STRAAFAALENKYGARLGVFAVDTSSETTI-AYRPGERFAFASTYKALAAGILFKQST ---EDELDHTIHYTESDLVDYSPVTEKRVASGMTVREIIAAALQYSDNTAANLMLDQLGGP -AGLAESLRSLGDTTTRVDRPEPGVNEAIPKDPRDTTTPAAIAGDLRSFLLGGALATPRRS -EMTTLMLGNTTGAPWIRAGVPSTWKIADKTGNASYGTRNDIAVAYPPGRAPIVIALLSDR -GTVDATSDDGLLADATRVVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI0013FE1C30 ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDTVQQLLLGDTLREPQRA -QLTEWMTGGARGTTGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAVRIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=UPI000993460E ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIRYAQSDLMEWAPITSQHVAEGMTVSELCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEGQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTAWTVGDKTGSGFKGETNDIAVIWPTGRPPIVVAVLTVP -DDPKSTQGKPTIAEATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Acidocella sp. MX-AZ02 TaxID=1214225 RepID=K5YKK0_9PROT ----ATSFLAESERRTGGRIGIYARNLATGRTL-SWRADERFVMCSTFKMSLVACVLSRVD -KGEERLGRFVQYGAAQLSNYAPVARLHLADGMTVGAMCQAAIEVSDNTCADLLLLSVGGP -AALTRFWRAEGDEVTRLDHTEPRLNFSPPGDPRDTTTPAAMAGDLQRFLLGDALSPASRA -RLTGWMLNCQTGGALLRAGLPKGWKVADKTGNNGKDALGDIAVAWPAPDRPIVICAYTQG -GQPKPEILPPILAGVGRMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007E95753 ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETSAGAEMTLDELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDP-KAEN------------- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=UPI00111C3B51 ---ELDIALAGIEERKHIRLGVIAHDPGRNLSY-IRRGEERFAMCSTFKVYAAAAILRLHT -QGRLTLDEPVPVAAADIVVNSPVTSAAQGRTLTLAQLCEASLTRSDNTAANLLLRRLGGP -AAITGFARSLGDTATRLDRWEPELNSAEPGDPRDTTTPTGLADGYRELLLGSGLPAAAKQ -TLTDWMRASVTSGERIRAGLPAGWTAADKTGGGSYGTVNDAGVVWSPDGAPLLLVLLTSS -TTPDAPNDNAALAETTAAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium novocastrense TaxID=59813 RepID=A0A100X4K3_9MYCO ----VEDRLGEMERRQNALIGVFATDLGTGRTI-AHRAHDMFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP -SGVTDFARSIGDQRSRLDRWEIELNAAVPADPRDTTTPEAIGAGYRSILTGNVLAEPQRR -QLEDWMRTNQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPAGERLLLAIMTRT -AAPDAPNDRQLVGDVASVLVA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=A0A3N1DWM6_9ACTN ----SSRSLAALERSHQARLGVFAWNTVSGRII-RHREKELFPTCSVSKTPAVAAVLRDLD -QEGEYLRKVIRYGAADVDRYAPVTGENLANGMKVSDLCAAAITHSDNTAMNLMLKELGGP -TAVTRFCRSIGDTVTRLDRWEPELNSAEPGRMTDTTSPTAIGKTYARLVLMGTLGTADRD -RLKGWLLANTTGDNRLKAGLPTSWTVAEKTGTGEYGTTNDVGVAWNTRGEPVVLAVLSTK -THAEAPADESLLAEAAHVIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=unknown TaxID=N/A RepID=UPI0014388B2B -------ALFELEKKFDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MTHLDTVITYTEADLMKSSAITKQHVQTGMKLRDLCDAAVRFSDGTAGNLLLRDLGGP -AELTRYLRELGDNETRMDRVEPAITEATPGDPRDTATPRSLGTDYQRLVLGDALPPEKRD -FLKDLLERSVTGAKRIRAGVPQGSKVASKTGTGDYGTANDIAVVWPPGREPILIAIMSSR -SSADAKYDEALIAEATAYVVK-- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI0011548006 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -LALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004822AB7 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTSFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAAVPPGWRVADKVGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQADAAARADVVTSAARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycolicibacterium sp. 018/SC-01/001 TaxID=2592069 RepID=A0A552ZZP0_9MYCO ------DRIAALARRYNARIGVYAADLGSDRSV-EVGADDMLAMCSTFKAYASAAVLQRAQ -QGRLALTDAVLVQRSDIRDHSPVTEPRVGSTMTLAELCQAALQQSDNAAGNLLLRTLGGP -PAITDFARSVGDDRTRLDRWETELNTAIPGDPRDTSTPRALGIGFRAVLTGDVLDSVHRQ -MLEDWMRANQT--SSMRAGLPQGWVTADKTGSGGYGTTNDVGIAYGPQGQRWLMSIMTRS -VTPDAESLRTLIGEIAAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164NII6_9NOCA ------ASLAELERRYGARLGVFAVATGTGATL-AYRADDRFAMCSTFKGLAAAAVLSRNP ---LSHLDTRVSFTRDEIRSISPVTERHVDTGMTIGQLCDAAIRYSDGTAGNLLLDDIGGP -AALTAYLRTLGDPWSPMDNYEPELNRDAPGDERDTSTPRALATDYRTLVLGTALSPEKRG -LLTDWLLRSTTGTGRIRGAVPGSWQVAHKTGTGDYGRANDVAIIYPPSTPPLVLAIMSDI -SNYNAQPSDQLIAEAAT------ ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=UPI0004C3C5C6 ------DALSELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSAITRQNVRTGMKLRDLCDAAVRYSDGTAGNLLLRDLGGP -AELTKYLRELGDTETRMDRVEPAITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD -FLTGLLERSVTGAKRVRAAVPAGSRVANKTGTGEHGTVNDIAVVWPPGREPVLIAIMSSK -SAADAKYDEALVAEAAAYVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000756C981 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAVAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8N8H7_9ACTN ---QVKKDLRSLEVSFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLRKAR -TKPGLMNRLIRWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQVGGP -KGLTRYFRTLKDATSRMDRWHPELNDWTPKDKRDTTTPAAIGRDLRVLTVGRALHAKDRR -QLLAWLLANKTGGERIRAGLPKSWTVADKTGTNSFGGGNDIAVVWPKKGAPVIMSIYTNR -TK-GLPTDNKTIAKTATILA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9H9_SHISO -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQVGRRIHYSQNDKVEYSPVTEKHLTDGMTVRELCSAAISMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKVLTGELLTLASRQ -QLIDWMEADKVAGPLVRSALPAGWFIADKSGAGERGSRGIIGALGPDGKASRIVVIYTRG -SQATMDERNRQIAEIGASVI--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB35_STEMA ------ADFAALEKASGSRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Actinomadura geliboluensis TaxID=882440 RepID=A0A5S4GF17_9ACTN ---EVTKQLTRLETTRRTRIGAYAIDTGSGRAV-GHRADETFPFASTFKAMACGAVLRKAR -QAPGLLDKVIRYTKDDLQEFSPVTEKHVDTGMTVAELCHATITQSDNTAGNLVLKEIGGP -AGLTAFLRSLGDTVSRSDRIEPGLNDWKPGEKRDTTAPRPWANDLRALTVGDALVPAERA -RLIDWLKATVTGDKRIRAGLPKSWTVGDKTGTGGYGSANDIAIAYPKGGAPLIIVVTTTR -KGAEADA---------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces rimosus TaxID=1927 RepID=UPI0004D91200 -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDRRPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium innocens TaxID=2341083 RepID=A0A498Q269_9MYCO ---DVRGRFAELEHRYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDTVVTYTGADIRSTSPITQQHVATGMSVGELCDAAIRYSDGTAANLLLADIGGT -SAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTARAIALDYQQLVLGDALPVDKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGVPHVLAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces antibioticus TaxID=1890 RepID=A0A101QFD4_STRAT ---STPKGLRELEARHGARLGVFARNIATGRTV-RHRAAELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHVADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAVTRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRA -LLTHWLRSNTTSGTRLRAGLPTAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL -PEQDAVRDDVLIRDTAALLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=A0A0E3BGJ4_9BURK ---TLSDELAALEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALLGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonadaceae bacterium CCH4-C5 TaxID=1768804 RepID=UPI00082BB94F ---TWNSAMEGIEQNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD -QGREKLDARVHYAPADVVDYSPVSGPRAGTGLTVSELCSATVSLSDNTAANVLLERHGGP -AALTRYLRMLGDPITRLDRNEPTLNEAAIGDVRDTTTPRPMLQTMQKLVLGESLSASSRA -WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVTCYLTR -SAVAPEQRDAAIAAVGRAVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphaerisporangium album TaxID=509200 RepID=A0A367FST0_9ACTN ------RLLRDLEKSSKGRIGAYAVDTATGRTI-GYRSGERFPLLSTFKALACAAVLDKAR -TTPGLMNRVIHWKSGDLKENSPVTEKHVDDGMTVAKLCEAAITYSDNTAANMVLRQIGGP -AGLTKYFRSLKDPITHLDRWETELNNWSLKEKRDTTTPAAIAHDLRKVTVDNALDPRDRA -QLNAWLRANTTGDARIRAALPKTWIIGDKTGSSSYGSANDIAVIHPTATPPIIMTIYTNH -HARDTAYDNKLIADTAAILTK-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis MBA4 TaxID=1323664 RepID=A0A0P0R7S6_9BURK ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRREPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLAPQQRE -QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKQTLPRDEVVVEAARIVFD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea wenchangensis TaxID=568860 RepID=A0A1I0IUQ2_9ACTN ----VTKELRALEKSYKGRIGAYAIDTATGRTV-AYRSGERFPLLSTFKAPVCAAALHKAS -TAPGLMDKVVKWTKAELKPNSPTTEKHVADGLTVAQLCEAAITLSDNTAGNMVLKQVGGP -AGLTRYFRSLKDPVSRLDRWETELNDWSAKDKRDTTTPAAISRDLRLLTWGDALNAKDRQ -RLIGWLRANRTGDTRIRAGLPKSWTIGDKTGTNSIGGANDIAVVWPDKAAPIIMAVYTTR -STPS--VDDKVLAKTATVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella typhi TaxID=90370 RepID=Q8KPE0_SALTI --rQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGS -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGRSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. BSW8 TaxID=2259645 RepID=A0A366C1I8_9RHOB --qALTDTISRLESALPARIGVAIRDSGSDWGW-GHRDSERFLMASTFKSVLCAAVLDRAD -RELLSLGDAVAIPPEAILDYAPVAETHVGGTMTLGDLCLATLDMSDNTAANLLIARLGGP -QEVTAFLRRIGDPVTRLDRTEPDLNLLDPADPRDTTSPAAMAATWQRLLLGDVLSPASRA -RLADWMSHGSVTASLIRASAPPDWTVSDKSGGGKDYTRNLVAMIQSPGRAPAIVAIYLSD -CPADWATRNAAVAEIGAAVI--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8992 TaxID=2184554 RepID=A0A3N8IZY1_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNKAAPDDERDTSTPVAMVDTLQRLLLGNALQAPQRT -QLTEWMAGGARGATGIAASVPPGWRVAEKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -QQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium mageritense DSM 44476 = CIP 104973 TaxID=1209984 RepID=X5KT70_9MYCO ----LDGQISALEQRDNALIGIFATNLDNGRTV-TNRADDLFAMCSTFKGYAAGRILQQVG -RGQLSLDKRVFVDPGAVVANSPVTGPRAGSEMSLGELCQAALQQSDNTAANLLLRTMDGP -AGITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPAALAAGYRRLLVEDALSPAQRG -QLEEWMRGNQT--SSLRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPDGQRLVLAVMTRS -QADDADNLRPLIGELAA------ ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. JP2-270 TaxID=2217913 RepID=A0A2U9SU14_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLRSGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNKVAPNDERDTSTPVAMVDTLQRLLLGDTLHEPQRA -QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Jiangella sp. KE2-3 TaxID=1623398 RepID=UPI000E356308 -----VAALTALEGDYDARLGVYAVDTGTGEIV-EHRADERFAFASTHKMLSAAAMLQATE ---TADLEQVIPIDAADLVGYSPVTEPAAGAGLTLLEIIDAAVTVSDNTAANLLFEQLGGP -DGLEAVVRGFGDETTSFDRIEPGLSDWVPGETRDTTTPRAMAANVQGLLLGDLLAEEDRT -LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVIAVYSNR -LDPEAESDPALIAAATEIVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0009078ADF ---ALSAQVKSVEQTLGARVGVSVFIPSQGVAW-NYHGDQRFPMMSTFKTLACAKMLADVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobiaceae TaxID=41294 RepID=A0A1H4PMJ6_9BRAD -------ALAAYERDTGGRIGVYAENLSTGAKI-AWRAEQRFVMCSTFKASLAALMLARVD -RGEDRLEDMVAYGPKDILDYAPVAKQNLAHGMSVSDMCKAVVELSDNTCANLLLARAGGP -AALTAFWRSTGDTISRLDHNEPELNRSPPGNPHDTTTPSAMAGNLRRFLLGPVLTPPSRE -HLTEWMVGCKTGNNRLRGGLPGDWKVGDKTGNNGKDASGDIAIAWPKSGGPVLVCAYTQG -GSPTAPQFEAVFKEIGAMV---- ->[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) TaxID=272568 RepID=B5ZHS4_GLUDA --gDIQARLQELESRSGGRLGVAILDTATGRLI-GNRVNERFAMCSTCKALVVAFVLSRID -RNEEWLNRRVTFTEHDLVSPFKATKPHVGPGMTIAELCEAAITVSDSTAANLLFASFGGP -EALTTYLRSLGDQVTRLDHVELALNIVKPGEIHDTTSPAAMAETLRKLLLGNALSDASRA -LLAEWMSGTKDATHRLRAGLPAGWRIADKPGTWEKIATNDIGVVWPPGRAPIVVTAYLGE -APGLVASREAILADVARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A0N9YFN9_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAVPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS -QGPKAENLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=2 Tax=Thalassotalea sp. ND16A TaxID=1535422 RepID=A0A099KCF7_9GAMM ------KTIEDVKLKLGADVGVAVYDISSDDLW-SYNGDTRFPLMSTFKTLACAKLLVDID -NGEQSFDTSVVIKKASLVTWSPVTEKHVGEKFSLRQACSATMIMSDNTAANIVLNGINGP -TALTQFMRSIGDPITRLDRVEPYLGEALAGDVRDTTTPNAMVKSLHKLLFGNALSAANKT -QLKQWMTDNKVSDSLLRSVLPVGWTIADRSGAGGYGSRGITAVVWSEQHSPLIVAIYLTQ -TEASFAQRNKAIAQIGKEIFSYy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia seminalis TaxID=488731 RepID=UPI000F5B21D0 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIVQLCEAMLQAGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT -QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -QRADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=A0A1H0I9Z3_9PSEU -------ALFELEKKYDARLGVYAMS-DTGRTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MAHLDTVVTYTEADLMKSSAITQRNVGTGMKLRDLCDAAVRHSDGTAGNLLLRDLGGP -AELTGYLRELGDTETRMDRVEPDITSAVPGDPRDTATPRSLGTDYQRLVLGDALPRDKRD -FLNDLLERSVTGARRVRAGVPAGSRVASKTGTGSYGTVNDIAVVWPPGREPLLIAVMSSK -RAADANYDEALVAEAAAYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium austroafricanum TaxID=39687 RepID=A0A2S8KTZ3_MYCAO ----LDQRIEALGQRHNAQIGLYALDLDTQRGI-EFGADEPFAMCSTFKAYAAAAVLQRTQ -TGELTLNDAIPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSDNAAANGLLRVLGGP -QAITAFARSIGDHRTRLDRWEVELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRQ -QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRS -AVPDAPSLRPLIGELAALVLS-- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum sp. B506 TaxID=137721 RepID=UPI00034C570C ---SIEARLKELEIRSGGRLGVAVLNVATGRLV-GHRIDERFAMCSTVKALVAAFVLARVD -RGEERLDRRVVFTERDLVPPSKATKPHVGPEMTIAELCEAAVTVSDSTAANLLLASFGGP -AALTTYLRSLGDPVTRLDRIELDLNIVKPGDLRDTTTPGAMAETLRRLLLGNALSHASRI -RLTTWMVEAKDAAQRLRLGLPAGWRIANKPGTWEGISTNDIGVIWPPHGGPIIVTAYLGE -APGSIGIQEKILSDVARIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0S1AXK9_9GAMM ------AGFAALEAESGGRLGVCLWHPASGARF-GQRMDERFPMCSTFKFLLAAAVLERAG -RGALSLDQRVPVRAADLLGNSPVTARHVGKDLGVRDLCRATLTTSDNAAANLLLPLVGGP -AGLTAFLRAQGDAVTLAARYEPDANRFAADDPRDTTSPAAMAGNLQRFVLGDALALAGRR -QLADWLIDNETGDARLRAGLPPGWRVGDKTGSNGRDTSNDIAVLWPRGGTPWVLAAFLQG -SALDDAGRDGILRRVGERAAA-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonadaceae bacterium TaxID=2026746 RepID=A0A2E2BL67_9GAMM ---DLDQRLAELERAADDRVGVALMNVTTGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -EGSETLDRRIVVEKGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIDSVGGH -EAVTAFLRAIGDDTTRLDRIEPDLNTDHEGDERDTTTPLAMMTTLRTLLLGDALSPSSRH -QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIGWPGDRGAVIAVAYTLM -PSATKTQRDETIAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium austroafricanum TaxID=39687 RepID=UPI00056BF22F ----VEQRLDALGRRHNAQIGLYAIDLNTQKSL-AYRDTESFAMCSTFKAYAAAAVLQRTQ -TGELTLNDAVPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSDNAAANGLLRVLGGP -QAITAFARSIGDHRTRLDRWEVELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRQ -QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRS -AVPDAPSLRPLIGELAALVLS-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHY8_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSG----------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AA8 TaxID=2720021 RepID=UPI00143B7D7E ---RISRQLRALEREHSARLGVFARNMVTGKTV-VHRPDERFPMCSTFKTLAVAAVLRDLD -HDGTFLAKRIHYTAEYAKAYDKITGKNVANGMTVEELCGAAISYSDNAAANLLLTELGGP -TAVTRFCRSVGDGTTRLDRWEPDLNSAEPDRITDTTTPRAIGRTYAQLVLGNALDAADRK -RLTGWLLANTTSDQKFRAGFK-GWTVADKTGSGSYGTSNDVGVVRTPEKAPVVVSVLTTK -HEPKAAGDDALVRKAAELLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. TaxID=391 RepID=A0A5C7TU25_RHISP ----GEAQLAALESRHPGRICVSILDMASGRRI-EHRAGERILMCSTFKALVAAFILARVD -KGEEELDRRIHYGKRDIIGGSAATKIHAGNAMTISELCAAAVTLSDNTAANLLLSSFGGP -KALTAFCRRLGDEITRLDRIEPALNYDKPDDLRDTTTAAAMLENLRRLLFTDVLSPASRS -QLAAWLITTKTGDSRLRTGLPRDWLAGDKTGTNGAGNANDIAVLWPSNRAPIIVTAYCEI -PAIAAGERDAVIATIGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A087NWY3_BURPY ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCDAMLRSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDHWEPELNKAVPDDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-169 TaxID=1571486 RepID=A0A542T2E7_9ACTN -------SIAALEQKHQRHLGVWAKNMRTGRVI-EHRADERFPMLSTFKTLLAASILRDHP ---ARTLQQRLTWEPADVVVNSPVTSLTTRNGLTVAQLAEATMTRSDNTAANELLHLIGGP -SGITRFARSLGDTVTRLDRWEPDLNSAIPGDPRDTTSPRAIAQTYTKLVLGDALDRADRD -QLTTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS -DDPAATPLDTPLADIAATVC--- ->[subseq from] class A beta-lactamase n=1 Tax=Fertoebacter nigrum TaxID=2656921 RepID=UPI00128B9806 ---QLMQTVDSIEQSLNVRVGLVVRDSASDWAI-SHRADERFLMTSTFKAMLCGAVLDRVD -DGALDLGETIKIEAEAILDYAPVTEGRVGDTMTVADLCLAALDMSDNTATNLLIDRLGGP -QSVTDFLRKIGDPVSRLDRREPELNTFAVGDLRDTTTPDAMVATWQAMLTGDALSSTSRA -QLVDWMSAGGVTGALIRASTPDGWQVADRSGSGNF-NRNIVAMVKPPGRAPYFIAIFLSD -AELDFETRNAAVIDLSRAVMD-- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea jiangxiensis TaxID=641025 RepID=UPI000B7DE6C7 -------ALFELEKKYDARLGVYAMS-DTGRTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MAHLDTVVTYTEADLMKSSAITQRNVGTGMKLRDLCDAAVRHSDGTAGNLLLRDLGGP -AELTGYLRELGDTETRMDRVEPDITSAVPGDPRDTATPRSLGTDYQRLVLGDALPRDKRD -FLNDLLERSVTGARRVRAGVPAGSRVASKTGTGSYGTVNDIAVVWPPGREPLLIAVMSSK -RAADANYDEALVAEAAAYVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Colwellia sp. 39_35_sub15_T18 TaxID=1856279 RepID=A0A1Y5D2Y1_9GAMM ----IIKKIEEQEHQLSARIGVSIYDVAANKLW-SYNGNTRFPLMSTFKVLACAKLLADVE -KGLQSFDTSTVITENSLITWSPITKNLVGEKMSLKQACSAAMIMSDNTAANIVLNGIKGP -KALTQFMRSIGDEVTRLDRIEPDLNEALDGDKRDTTTANAMVKSLHTLLFGDVLSQASKT -QLKQWMIDNKITGSLLRSVLPENWSIADRSGSGGYGSRGITAVVWSDKRTPLVISIYLTQ -TEASFTQRNKAIAIIGKEIFTVy ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis niigatensis TaxID=369932 RepID=A0A2N3WQ83_9PSEU -----QPDFAALEKAFDARLGVDAIDTGDGREV-AYHADDRFAYASTHKVFNAAAILHRGD -----DLTRTVTIRQSDLVPNSPITEKHIGEQISLQSVLDAALRYSDNTADNLMFREIGGP -AGLAAEVRRLGDTVTHVDRIEPALNETSPGDVRDTTTPRVWAKDLRAVALDSGLPADKQA -VLTKIMRANTTGAHVIRAGVPADWQVADKTGTADYATRNDIAVLWPPHRAPIVLAVLSDR -AHKDAKTDDNLIAQAAAAVVK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. HI2761 TaxID=2015360 RepID=A0A228Q8W5_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPQCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCTAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGEVLHEPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGFGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVTAAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. WAY2 TaxID=2663121 RepID=UPI00131FCE32 ----LDSRIAELEARHSTRIGVTAVDPTTGAVY-RHRGAERFALCSTFKTYAAAEVLRRTS -EGTSSLDKAVPVEASALVENSPVTAAAVGTSMTLAELAEAALTRSDNTAGNLLLTEIGGP -QAITALARSIGDDTTRLDRWETELNTALRGDPRDTSTTDGLAEGYRALLLGDELEPTHRR -QLLDWLRASTTSDTRIRAGLPPGWSAADKTGTGRFGTANDAGVVWDREGNPLVLVILTDT -STEAAQPNSDAIAETTTAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis antarctica TaxID=1854586 RepID=A0A263D0W0_9PSEU ----------GLEREFDARLGVYAVDTGTGREL-AFHADDRFAFASTVKALAAGVTLQRNT ---LGELEERVRFGPGDLVPHSPVSERHVDTGMTLREAMDAALRYSDNTALNLLLPEIGGP -DGLTAALRGIGDATSRSDRTETELNETAPGDPRDTSTPRALAGSLRAFALGDTLPEDKRA -VLTELLRTNTTGETLIAAGAPDGWVVGDKSGAADHGTRNDIAVLWPPDRAPVVMAVMSDR -RAEDAEYEDALVARAATAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. YIM 130001 TaxID=2259644 RepID=A0A399GL58_9ACTN ---ELGRQLGELEERYAARLGVFARNMATGRTV-RHRADERFPMCSVFKTLAAAAVLRDLD ---DSHLGRRIHYTQGDVDKYAPVTGKNIAGGLTVRELCAAAVSESDNAAANLLLRDLGGP -RAITRFCRSLGDGVTRLDRWEPELNSAEPWRRTDTTSPRAVGTTYARLILGRALDVPDRA -KLTGWLVANTTNMERFRAGLPDDWILADKTGGGEYGVANDVGVVHPPHGAPLVLSVLSTK -LDPAGPTDNPLVAEAARLVAAH- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium kansasii TaxID=1768 RepID=A0A163UDZ7_MYCKA ---DVQGRFAELEHRYAARLGVYVPASGTTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDKVLTYTCADIRSTSPITQQHVATGMSIGELCDAAIRYSDGTAANLLLADIGGT -TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTAHAIALDYQQLVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGVPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5755 TaxID=1519475 RepID=A0A0M9XUR9_9ACTN -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLSRVIHYTEAEVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAGNLLLRELGGP -TAITRFCRSLGDPVTRLDRWEPELNSAEPDRRTDTTSPYAIARTYQRLVLGNALDRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK -PTPTAPGDTPLIIKLATV----- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. 1121.2 TaxID=1938831 RepID=A0A2G6ZUA1_9ACTN -------RLSDLEQEYSARLGIFAHDTGTGRTV-AYRADEHFPICSVFKTLAVSAVLRDLD -RDGEYLARRIRYTAKYVTDYAPVTEENVAAGMTVEELCAAAVSQSDNGAANLLMRELGGP -TAITRFARSVGDATTRLDRWEPELNTAEPWRTTDITSPREIGRTYARLVLGRALPTQDRT -RLTGWLIANTTNTERFRAGLPAGWVLADKTGGGSYGVANDVGVVWPPGRPPLVLAVLSTK -YAPEGPTDNPLVSRAAALVADE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QB40_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWWVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio mediterranei TaxID=689 RepID=UPI0007854414 ---TLDESIASIEQRISGRIGVSVLDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD -SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP -QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFKGALNQGSKN -QLMAWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGFTGAIWADNRKPLVISIYLTQ -TDLSMSKRNQIINEIGGLIFETy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=A0A0K8PXP2_STRAJ -------RLADLEREYGARVGVYALATGTGATA-VHRSDERFAFCSVFKALAAAAVLHHRS ---LDGLDRRVTYTRADLKSTTPITGRHVATGMTLRQLCDAAVRYSDGAAGNLLMRDLGGP -AKLTAYLRGLGDTVSRMDHYEPELHDVPPEDPSDTTTPRAIATDFHKLLLGTALPAGERA -LLTDWLSRNATGARRIRAGLPKGWQVADKTGTGNYGRANDIAIVRPTRTEPLVLAVMTDR -RGYDAAPSDALIAEATAR----- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CB01201 TaxID=2020324 RepID=A0A2M9JD36_9ACTN ---DVADTLRQLEASHDVRIGAYALDTGTGRTV-SYRGNESFPSLSTFKAMACAAVLDRAR -YEPGLLGKVVHWKASDEVANSPVTKGQGDKGMTVAELCRAAITRSDNTAGNMVLHQIGGP -QGMTRYYRSLGDPVSRLDRWEPELNDWRPGERRDTTAPAAMGRDLARTSLGCGLVPADRD -TLNTWLRGTVTGDERIRAGLPKDWTVGDKTGTTDYGSANDIAVAWPKSGHPVIIAIYTNH -AAAEAPADNAVIASTASALV--- ->[subseq from] Beta-lactamase n=1 Tax=Thalassotalea sp. 42_200_T64 TaxID=1856287 RepID=A0A1Y5GI18_9GAMM ---SMVKTIEEVKQKLGADVGVSVYDVSSDDLW-HYNGDTRFPLMSTFKTLACAKLLADIH -NGEQSFDTSVVIKKESLVTWSPVTEKHVGESFSLRQACSAAMIMSDNTAANIVLKGINGP -TALTQFMRSIGDKITRLDRIEPYLGEALDGDVRDTTTPNAMVKSLRELLFGNTLPAASKT -QLKQWMTDNKVSDSLLRSVLPIGWLIADRSGAGGYGSRGITAVVWSEQRSPLIVAIYLTQ -TDASFAQRNKAIAQIGKEIFTFy ->[subseq from] IMI-5 beta-lactamase n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A125S6J9_ENTCL ------DEIKNLEKKFNGRIGVYALDTGSGKSF-AYRANERFPLCSSFKGFLAASVLKGSQ -DKQLNFSEIVNYNTRSLEPNSPITAKYKEQGMPLGEMAAAALQYSDNAATNIILERIGGP -VGMTKFMRSIGDEEFRLDRYELDLNTAIPGDERDTSTPEAVGKSLKNLALGNILNDSEKE -TYQTWLKGNTTGAARIRSSVPREWVVGDKTGTCGYGTANDYAVVWPDDRAPLIISVYTTK -YEKDAKHEEEFIAEASRIAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00075354F6 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDMLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1164985.4 TaxID=1834069 RepID=A0A1A3T6C3_9MYCO ---QLADRLGEMERNHNALIGVFAVNLDTGRTV-AHRPRDPFAMCSTFKTYAAARVLQGAE -RGELALTDRVPVAQSDIVPNSPVTGEHVGQTMTLAELCQAALQQSDNAAGNLLLRTIGGP -SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEALGGGYRSLITGNVLGEPQRR -QLDDWMRANRT--SSVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT -AAPDVPNDRRMVGDVGSMLV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=A0A1A2FVW7_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRTI-RHRPDEMFAMCSTFKGYAAARVLQMAE -RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAVPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS -QGPKAENLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI00096D267B ----IDDQLAELERRDNVLIGLYAANLQSGRTI-RHRPDEMFAMCSTFKGYAAARVLQMAE -RGEISLDNRMFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAVPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPGGQRLLLVMMTRS -QGPKAENLRPLIGELTALV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aquabacterium sp. TaxID=1872578 RepID=A0A5C8BJH1_9BURK ---------EGIEHNAQGRLGVSMLDTETGLAL-GWRQDERFAMCSTFKLLLAGWMLSLVD -QGREKLDARVHYAPADVVDYSPVSGPRAGTGLTVGELCSATVSLSDNTAANVLLERHGGP -AALTRYLRALGDPITRLDRNEPTLNEAAIGDVRDTTTPLAMLQTMQKLVLGESLSASSRA -WLQRWLIETSTGDKRLRAGAP-GWKVGDKTGTAGSGTANDVAVLWPPHRGAVLVTCYLTR -SAVAPEQRDAAIAAVGRAVVS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lechevalieria xinjiangensis TaxID=402600 RepID=A0A1H9M5K7_9PSEU ------DALAELERKFGARLGVYAT--GAGGTV-EHRADERFAFCSTFKGLATAAVLHRNP ---MSHLDTVVTYTEAELMKSSAITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDVGGP -AELTRYLRELGDTETRMDRVEPDITSATPGDPRDTATPRSLGTDYRRLVLGDALPPEKRD -FLTDLLERSVTGAKRVRAGVPQGSRVASKTGTGSYGTVNDIAIVWPPGGEPLLIAVMSSK -DAADAGYDEALVAEAAAYVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012621F4E ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINNTLNTLVLGETLSSASRQ -QLKTWMQDNKVADVLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiaceae bacterium TaxID=2030806 RepID=A0A522S8B4_9BURK ----LDGAVTQAELALRARIGVALIDTASGTVW-QRRGGERFPLNSTHKVFSCAAALARAD -RHEADMDAGIPIDTTTLVAYSPVTAKVPAGGMSLRQLCRAAVSFSDNTAANLVAGAIGGP -TAVTAFLRAIGDGTTRLDRLEPELNQATPGDVRDTTTPLAAAESLQSLLLGDALSRPARA -ELRQWMLNDRVADALLRSGLPKDWRVADKSGAGGHGSRAIIAVAWPSERPPVVIAIYITQ -TDASMAARNHAIAHIGSALATAf ->[subseq from] Beta-lactamase n=1 Tax=Nesterenkonia salmonea TaxID=1804987 RepID=A0A5R9BIB6_9MICC ---TVSESFKELESRYDARLGVYAVDTGSGEEV-TWRDDERFAYTSTIKAIAAGALLDQVG ---LDGLETEVPIQTGDMVPHAPVTENHIGQTLTLAELTEAAVTVSDNPAANYLFDELGGP -AEFDAVLEDLGDDVTEVVRREPELNEATPGDDRDTTTPRAISENLREYLFGTTLSDEEKS -QLRQWMIDSETGDALIRANLPSEWTIGDKSGNGGYASRGNIAAIWPPEGDPIVIAVLSSR -DEPDAEHDDRLIAEAAEVAVS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium rosettiformans W3 TaxID=538378 RepID=A0A4S8QAH6_9RHIZ ----IVASAKRVEQKLDMRVGFTVIDTGDGTVT-GYRQNERFAMASTFKAFACAAALSRGE ----AVLAKKTTIRQADLRPYSPVTERRVGTSISTRALCEMTLRTSDNAAANAILKALGGP -AEVTGFLRQIGDETTRLDRYEPELNEAKPGDPRDTTTPQAMAETLRRLLLQDVLEPQARD -QLEEWMAGNAVAGGLLRSRLPEGWQIADRSGAGGHGTRGVIALVRPPQGAPLIVAIYMDR -TDHPLKVRDAAIAEIGAAIFETy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. HI2500 TaxID=2015358 RepID=UPI000B7A70C3 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAILARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFVRASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGDTLQEPQRA -RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio alginolyticus 40B TaxID=674977 RepID=D0WWU8_VIBAL --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAMLNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A4Q2ADU8_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGDTAFRLDRWEPELNLAAPGDERDTSTPVAMVDMLQRLLLGDTLHEPQRT -QLTEWMTGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=W0TY33_PSEAI --rQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGS -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGRSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF6AA6 ---RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSLTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFB19A ---RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora cretacea TaxID=28444 RepID=UPI0004C306A3 ------ADLRALETSFKGRIGVYALDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKKP ----DILGKRILIRKKDLLPNSPETQKHVGSRMTVAALARAAVTKSDNAAANLLLRQIGGP -KGLTRYFRGLDDHVSRLDRNEPGLNLWHPREVRDTTTPAAIAADLKALTVGGALDAGDRR -TFTGWLVANETGDNRIRAGLPKSWRIGDKTGTGGYGTANDYAVIWPKGSKPIIMAIYTNR -TDRNAAADESVIARAATIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides TaxID=670516 RepID=UPI0004AA4337 ------SELASLEKDFGGRVGVFALDTGSGATL-GHRADERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYAQSDLMEWAPITSQHVAEGMTVSGLCDATLRYSDNTGANLLIAQLGGP -KQTEKFVRSLGDNVSRMDRTEDQLN--VPDGDLDTSTPQQLVTNLRRLVLDEGLDAQGRD -LLTDWLKRNTTGDQSIRAGVPTGWTVGDKTGSGFKGETNDIAVIWPTGRAPIVVAVLTVP -DDPKSTQGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0010FE1535 ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHSVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHDPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] FRI family carbapenem-hydrolyzing class A beta-lactamase n=6 Tax=Enterobacteriaceae TaxID=543 RepID=UPI000F04DCE3 ------EEMRELETSFGGRIGVYILNPKNGKEF-AYRQDERFPLCSSFKAFLAASVLKRTQ -EKSVSLDDMVEYSGRVMEKHSPVSEKYRKTGASVQTLAKAAIQYSDNGASNLLMERIGGP -EGLTAFMRSTGDTDFRLDRWELELNTAIPGDERDTSTPKAVAMSLKNIAFGSVLDAKNKS -LLQEWLKGNTTGNARIRAAVPDKWVVGDKTGTCGYGTANDVAILWTDANSPAVMAVYTTR -PNQNDKHDEAVIKNAAKIAIK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Desulfovibrio sp. TaxID=167968 RepID=A0A212J2R0_9DELT --kNLQKMLAELEASSGGRLGVAASVSNGDKIL-SYRGNERFPMCSTFKVLAAAAVLRDKT ----NILEQRIHFAKSDIQPWSPVTEKHLEDGMTVSELCKAMLQHSDNTAANLVLAQLGGP -AGLTSIARSFGDTTFRLDRWEVELNTAIPGDARDTTTPLAMRRTLNGLLCGNQLKAPARK -QLTDWMLGCATGAGRIPAGAPQGWRSAHKSGSGENGTANDVGVLLPPQNKPLTVALYLTG -SRLTGPENDKILAQATRLVC--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. UCD-KPL2560 TaxID=1885315 RepID=UPI0008247703 ----TGQAFAALEARAGARVGVVALDTGDGHAI-GYRADERFAFASTNKVFIAAAVLDAAT ---GSDLDEVVHYDRGDLLSYAPVTRPAVDTGLTVRQLVDAAVRSSDNTAANLLVERLGGV -DAVARWLRSTGDDVTDVSRTEPDLNTAVPGDRRDTTTPAQSATDLRAVLLGDVLDADDRA -LLLGSMRGTTTGDGTIRAGVDPAWTVADKTGTASYGVRNDIAVVTPPGRDAIVLVVMTSH -PASDAEPSDALVAEVTRTAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F6514C ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAC--------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ACS1612 TaxID=1834117 RepID=A0A1A1YZC2_9MYCO ----VADRIAALERRHNAYIGVFAVDLGGGRSF-SHRGQQPFAMCSTFKAYAAGRVLQMVE -QGQLTLDQQVFVDPAGVVANSPRTEPRAGGNMTLDELCQAALQVSDNTAGNLLLNTIGGP -PAVTAFARSIGDQGSRLDRWETELNSAVPGDPRDTSTPEALGGGYRALLTGDALAPAQRQ -QLEDWMRANET--SSMRAGLPQGWTSADKTGSGDYGTANDVGVAYGPEGQ-LLLAVMTRS -QLSDAASLRPMIGEVTALL---- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI0010FE94C1 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKTIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase class C n=2 Tax=Burkholderia TaxID=32008 RepID=A0A318J0R0_BURPY ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAGAILARGA -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLRSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDHWEPELNKAVPDDERDTSTPVAMIDTLQRLLLGDTLREPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium goodii TaxID=134601 RepID=A0A0K0XBN6_MYCGD --------IVDLEQRHNAVIGAYAVNLDSNRTV-AHRADDSFAMCSTFKAYLAARVLQGAQ -RGELSLDDRVFVDPSVLLPNSPITEEHAGGELTLAELCQAALQRSDNAAANLLLNQIGGP -PAVTEFARSIGDQRTRLDRWEVELNSAVPADPRDTSTPAALAGGFRAFLTGDVLNPPQRQ -LLDEWMRANQT--SSMRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRS -GGDDAAGFRPLIGELTAMV---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas citrea TaxID=43655 RepID=A0A5S3XLG9_9GAMM ---NISKKIEEIESQLDARIGVSIYDVTGNKLW-NYNGDTRFPLMSTFKTLACAKLLVDVE -EGLQSFNTSSVITKSSLVKWSPVTKKHVGKQFTLKQACSAAMIMSDNTATNIVLAGIKGP -KELTHFMRSIGDNVTRLDRVEPFLNEALDGDKRDTTTPTAMVKSLHTLLFGDVLSQDSKV -QLKQWMIDNKVTGSLFRSVLPEGWSIADRSGAGGYGSRGITAVVWSDKRSPLIISIYLTQ -TDASFALRNKAIASIGKEIFTVy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium iranicum TaxID=912594 RepID=A0A1X1WCA5_9MYCO ----VEERIEALAKRHNAQIGLYTVNLDSEESL-GYRDTEVFAMCSTFKAYAAAAVLQRAQ -QGRLALSDTVPIEPADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRALGGP -PAITEFARSIGDDRSRLDRWEVELNSAVPGDPRDTSTPRALGAGYRAILTGDVLQPAGRQ -QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRMLLAFMTRS -AVPDAASLRPLIGELATLVMA-- ->[subseq from] Beta-lactamase n=1 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5KDF8_9ACTN -------AVRELERAHDVTLGVSATNLATGTRL-AHRSGDRFPILSVFKSIAAAAVLRDLD ---ESRLEHRVWYPPADILLNSAITAEHVDTGMTVAELCDAAIRFSDNAAGNLLLREIGGP -RGLTAFARSTGDDATRLDRWEIELNTAEPGDVRDTSTPAALARTFAGLLVGDLLRPRDRR -RLRDWMLANTTSGPRFRDALPDGWRLADKTGAGDYGANNDAGVAWNPAGQPIVIVAMSRR -AERDAPRVDAALADVARLVVR-- ->[subseq from] Beta-lactamase n=2 Tax=Comamonas TaxID=283 RepID=A0A096FI94_COMTE ---TLSDELAVLEIQAQGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARMLYLAQ -RDEIRLWRKLYYSPSEVVAWSPISEKRAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTTRLDRNEPSLNTALAGDERDTTTPQAMLQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SQLDGAGREAVLARAGEAVKR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces bottropensis ATCC 25435 TaxID=1054862 RepID=M3EKI1_9ACTN ----LAGRLGELEREYSARLGVFAHDTATGRTV-AYRADERFPLCSVFKTLAAGAVLRDLD -RDGEYLARRIRYTEEYVKAYCPVTGENVSAGMTVGELCAATVSHSDNGAGNLLLRELGGP -TAITRFCRSLGDRTTRLDRWEPELNTAEPWRTTDTTTPRAIGGTYARLLLGRALPDADRD -LLTGWLVANSTNVERFRAGLPADWTLADKTGGGSYGVANDVGVVRPPGRPPLVLSVLSTK -YDPEGPTDNPLVARAAGLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI00130289F9 ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTRPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHDPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. AX6 TaxID=2653171 RepID=A0A654D3S6_9SPHN ------AELAAIAAEVGGRLGVHAFDTTTSAAI-GIDAGSRYAMCSTFKAPLAAAILTQVD -AGTLHLDQSVRFTRADLVPYAPVVEAALDRGLSVEALCKGAVEISDNVAANLLLALIGGP -AGFTRFVRARGDAVTRLDRIEPELNLVRGGDVRDTTTPAAMVGLMGAVLTGKLLTPASRD -RLIGWMVASPTGRERLRSGFPADWRAGDKTGTSGEGYFNDIAIMWPPDRAPILVACYLDA -PGLDPEAANAAHAKVGALIARRf ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI00084D317B --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSIFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITLSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. A9 TaxID=1365108 RepID=A0A0B1YLE5_9BURK ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMALLQSNDKGAGNLLMGVLGGP -QAVTSFAHESGDPAFRLDRWEPELNQAAPGDLRDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRVADKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PSADAAARADVVASAAHIAT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1Y1BND1_9BURK ---AAQAELAALEKASNGRLGIAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIAQLCEAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHGSGDTTFRLNRWEPELNQAAPGDERDTSTPVAMVDALQRLLLGDTLHEPQRT -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQANAAARADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000F512F49 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSGAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Saccharothrix saharensis TaxID=571190 RepID=UPI00114DE8F7 -------HLIGLERRFDARLGVYAVNTGTGAAV-EHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVRYTEGDLMASSFITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYARALGDTVTRSDRFEPNLTTAVPDDPRDTTSPRAIGEDYREIVLGDALDADKRA -FLRDLLERNATGALRVRAGVPQGWTVADKTGTGDHGTVNDIAVVWPPDAAPLVVSIMSSK -AGADAAYDQALLAEAAAYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces nanshensis TaxID=518642 RepID=A0A1E7KV91_9ACTN ------------------------------------------------------------D -GGEALLDARVRYSEDDLEEHSPVTGEHLDHGMTLGQLCDAAVRQSDNTAANLLLRELDGP -AGVTRFCRSLDDRVTRLDRWETELNSAEPGRTEDTTSPRAVARTYARLVLGDALEPPQRR -RLTDWLKRNTTGDDSLRAGLPEGWSIGEKTGSGAYGTNNDVGVAWAGDRTPVVLAVYTTK -HSAGAEPDYPLIAAATRLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Acidocella facilis TaxID=525 RepID=UPI00047895C5 ----ATSFLAESERRTGGRIGIYARNLATGRTL-SWRADERFVMCSTFKMSLVACVLSRVD -KGEERLGRFVQYGAAQLSNYAPVARLHLADGMTVGAMCQAAIEVSDNTCADLLLLSVGGP -AALTRFWRAEGDEVTRLDHTEPRLNFSPPGDPRDTTTPAAMAGDLQRFLLGDALSPASRA -RLTGWMLNCQTGGALLRAGLPKGWKVADKTGNNGKDALGDIAVAWPAPDRPIVICAYTQG -GHPKPEILPPILAGVGRMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. 10N.286.48.B8 TaxID=2056189 RepID=UPI000D360D1B ------ESIEQIESRVSGRIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLDLESKVGVNSDELIAWSPVTKAFVGKEISLRGACAATMAMSDNTAANIVLASIGGP -NGLTEFLRSTGDRKTRLDHIEPDLNHARPGDERDTTTQKTMVKTLNKLLYGSALSEESKA -QLKTWMIDNKVSDGMIRSILPDGWKVADRSGAGAYGSRAITAIVWSENRAPLIISISLTE -TELTIPERDTVINEIGELIFDEy ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5FCB8_9ACTN ---QVKKYLRSLEVSFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLQKAR -TEPGLMNRLIKWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQVGGP -KGLTKYFRTLKDTTSQMDRWHPELNDWTPKDKRDTTTPAAMGRDLRVLTVGRALHAKDRR -QLLAWLLANKTGGERIRAGLPKSWTVADKTGTNSFGGGNDIAVVWPKKGAPVIMSIYTNR -TK-GLPTDNPTIAKTATILA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0010C7B48E --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIL--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI000F0BB515 --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEVKKADLVTYSPVLEKQVGKPITHSDACFATMTTSDNTAANIVINAVGDP -KSITDFLRQIGDKETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLAQ -TEASMAERNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Phaeobacter gallaeciensis DSM 26640 TaxID=1423144 RepID=V9WGU6_9RHOB ---DLAETIRSWETALDARLGVLLIHPATGWEI-AHSADDRFPLNSTFKPLLCAAILSQVD -QGTEDLTARVEIRRKDLVSHSPVTERYIGTTRSLAQLCEATITRSDNTAANLLLERIGGP -EGFTEFMQISGDLITRLDRWETGLNSATPDDHRDTTTPRSVLSTLHVALSGTMLSGPSSA -QLADWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRVPQGSEYLAAIYITE -TDANFARRNQAISDIGRAMVA-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix saharensis TaxID=571190 RepID=A0A543JQP1_9PSEU -------HLIGLERRFDARLGVYAVNTGTGAAV-EHRADERFAFCSTFKGLAAAAVLHRNP ---LSHLDTVVRYTEGDLMASSFITRQHVATGMTIRQVCDAAVRHSDGTAGNLLLRDLGGP -AGLTAYARALGDTVTRSDRFEPNLTTAVPDDPRDTTSPRAIGEDYREIVLGDALDADKRA -FLRDLLERNATGALRVRAGVPQGWTVADKTGTGDHGTVNDIAVVWPPDAAPLVVSIMSSK -AGADAAYDQALLAEAAAYVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium mageritense TaxID=53462 RepID=A0A5C7XW56_9MYCO ----LDGQISALEQRDNALIGIFATNLDNGRTV-TNRADDLFAMCSTFKGYAAGRILQQVG -RGQLSLDKRVFVDPGAVVANSPVTGPRAGSEMSLGELCQAALQQSDNTAANLLLRTMDGP -AGITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPAALAAGYRRLLVEDALSPAQRG -QLEEWMRGNQT--SSLRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPDGQRLVLAVMTRS -RADDADNLRPLIGELAA------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI000F56A4C8 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTSFRLDHWEPELSKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMAGGARAATGIAAGVPPGWRVADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=A0A3E2MR93_MYCMR ---DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI00045FDC78 ---DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. RTd22 TaxID=1841249 RepID=UPI000ACBB813 ---DVTRRLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPMCSVFKALAAAAVLRDLD -RDGEFLAKRIHYTEEFVRKYAPVTGKNIAGGLTVEQLCAAAVSESDNAAGNLLLHDLGGP -TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRE -RLTGWLVANTTNIERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK -YDPQGPTDNPLVARAAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=UPI001144004A ----LTGRLRELEKEHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD -HDGSFLAKRIRYTAAYVERFSPRTGENLAHGMTVAGLCDVTLRYSDNAAANLLLRELGGP -TAVTRFARSIGDGVTRLDRWEPELNSGEPWRDTDITTPRAIGRTYGRLVLGTALTPRDRD -RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGVAWPPTGGPVLLAVLTAK -PEEDAAADNPLVAGAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf94 TaxID=1736250 RepID=UPI0006FBF0EC -----GAALARIAGDLGGRAGIAVLDTGGDPAL-LHDAEGAFPLCSTFKLLLAAAILARVE -AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAAIGGP -AALTAYGRDLGDPVTRLDRTEPDLNAAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA -RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG -SDTTSEARDAAHAAIGRVIAATy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL90 TaxID=2487344 RepID=UPI000F5BA4D6 ----VDDQIAELERRDNALIGLYAANLDSGRIL-TNRPDEIFAMCSTFKGYAAARVLQMVG -RRQISLDNRVFVDPEAIVPNSPVTETHAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSVGDERTRLDRWEVDLNSAIPGDPRDTSTPAALAVGYRAVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPNGQRLLLAVMTRS -QADDADNLRPLIGELTALV---- ->[subseq from] Serine hydrolase n=1 Tax=Aeromicrobium sp. Co35 TaxID=2590901 RepID=A0A554S799_9ACTN --------LSAEAAEAGVDLSATVTDLSSGATF-QVGGQEPVKAASIIKLPLLAALMDEAD -QGRLSLDEVVTIEASNIVGGSGTLRDREPLDITIAELMELMVQVSDNTATNVLIDRAGGF -DGVNEYIEGLGFEHLWLGRKMI--HPASPPLQENWITSGEVNELVRMLYEHEVLSPESSE -HIISLMKGQLV-DTKFGAVIPRE-VLANKTGELVD-VSHDSGLILVPGRE-VALTVTTSF -DPIERPQVDVYVQRAASIVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Aeromicrobium sp. Co35 TaxID=2590901 RepID=A0A554S799_9ACTN ------------ARANGIDIGVAIEDLSEDRQL-FLGAQDRFTTASTIKMSLAAAVMHQVE -RGQLSLDDVVTITEDERYGGSGTLKDNPFPQVSVGTLLELMVTVSDNTATNKLVDVVGGF -EAINTLTQDAGIAQRDLHFGRKMFGPVVPPDGDVWLTPRGMNRLMVLFYDPEFLSAESAQ -HIVELMLAQQV-KTKLGATVPAE-VLAHKTGENDV-VSHDVGMLLVPGQ-EMTLSVFSRG -AEDVQATANPYLQRIGAAVYAY- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. URHB0044 TaxID=1380386 RepID=UPI00048A86B7 ----IHDRIDALQQRHNAKIGVYGVDLTTGRSI-TYLDGERFAMCSTFKGYAAARVLRGSE -RGQLRLDDAVPIESADIVSNSPVTEPAVGGTLALADLCQAALQRSDNTAANLLLRAIGGP -PAVTDFARSIGDDETRLDRWETELNSAVPGDLRDTSTPRALGGGYQNLLTGDALAPASRD -LLETWMRANVT--SSMRAGLPPGWTSADKTGSGDYGSTNDVGIVYGPDGRRVLLSIMTRS -RTDDAENLRPLIGE--------- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. SCL1-1 TaxID=2592812 RepID=A0A544XQ11_9ACTN ---DVTAALRALEASFKGRIGAYAIDTATGKTI-GYRAGERFPLLSTFKAVAAGAVLARTT --DRELTRKVVHWTADEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -RGLTRYFRTLKDPVSRLDRWETDLNIWSPKERRDTTTPASVARDLRVLTTGGVLGAKDRS -RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVIWPANAAPIIMAIYTNR -RAADGATADSVVARTATLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Amel2xB2 TaxID=1305829 RepID=A0A327UEK0_9ACTN ---EVARGLRKLERQHSARVGVFARNMRTGTTL-VHRADERFPLCSTWKPLAVAAVLAGRG -GGEALLDARVRYSEDDLEEHSPVTGEHLDHGMTLGQLCDAAVRQSDNTAANLLLRQLDGP -AGVTRFCRSLDDRVTRLDRWETELNSAEPGRTEDTTSPRAVARTYARLVLGDALEPPQRR -RLTDWLKRNTTGDDSLRAGLPEGWSIGEKTGSGAYGTNNDVGVAWAGDRTPVILAVYTTK -HSAGAEPDYPLIAAATRLL---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rutilum TaxID=370526 RepID=A0A1H6L8B8_9MYCO ----LDSRLRDLEREHNALIGVFATNLDSGRTV-AHRAAESFAMCSTFKAYAAARVLQLVE -RGGLTLDQRVFIDAADILANSPRTQTQVGGEMTLDELCQAAVQVSDNAAANLLLRTLGGP -QAITAFARSIGDERSRLDRWELELNAAVPGDPRDTTSPEAIGGGFRAILTGTVLAEPQRR -LLEQWMRANET--SSMRAGLPDGWTTADKTGSGDYATTNDVGIAYGPSGERLLLALMTRT -AGADAPGLRPVIGEVAALLV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=A0A4Y3REC6_9ACTN ----LTGRLRELEKEHSARLGVFAHDVRTGRSV-AYRADERFPMCSVFKTLAVAAVLRDLD -HDGSFLAKRIRYTAAYVERFSPRTGENLAHGMTVAGLCDVTLRYSDNAAANLLLRELGGP -TAVTRFARSIGDGVTRLDRWEPELNSGEPWRDTDITTPRAIGRTYGRLVLGTALTPRDRD -RLTGWMLANTTSGERFRKGLPADWILADKTGGGRYGGNNDVGVAWPPTGGPVLLAVLTAK -PEEDAAADNPLVAGAAALVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sp. MB263 TaxID=308754 RepID=A0A1V0HUS4_9RHOB ---TLADTVERVESRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD -AGELSLQTELPVRKSDLLDYAPVAKKRAGGEMTIAELCLAAIDMSDNTAANLLIEHLGGP -QAVTRFFRSAGDRISRLDRTEPALNTFNAADLRDTTTPAAMTETLRGLLLGDVLSRSSRT -QLAAWMSQGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDASPWIVTIFVSD -VDADAQTRNRALQDIGRAVM--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces himastatinicus ATCC 53653 TaxID=457427 RepID=D9W718_9ACTN ---DVTRQLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPMCSVFKALAAAAVLRDLD -RDGEFLAKRVHYTEEFVRKYAPVTGKNIAGGLTVEQLCAAAVSESDNAAGNLLLHDLGGP -TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRK -RLTGWLVANTTNIERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK -YDPQGPTDNPLVARAAALVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. V19_P1S1T109 TaxID=1938672 RepID=UPI000B8EA25D ---QLTQSVKDIESDWQGRIGVYAYDIYGSFTF-GYREQERFPLCSSFKSLLAAAILQKSQ -NQLLNLDTSIDFSERDLEFWSPITEENHAEGMTIGQLAQAALQYSDNGATNILLERIGGP -KGMNTFMKSIGDEDFRLDRWELELNTAIPGDERDTSTPKSMATSIGKLSFGNVLSASHQE -LFHDWLIGNTTGDNRIRAAVPKQWQVGDKTGTCGYGAASDVAVIWREKASPLVIAIYTHK -SEPSAKHSDKIIAEVAKETLQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 155 TaxID=1157943 RepID=UPI000368BC85 ----LDDQIAGLEQRNNVLIGIFAANVDSNRTV-AHRADETFAMCSTFKGYAVGRVLQQVD -RAQLALDTRIFIDPSAIVANSPVTERRAGADMTIGELCQAALQHSDNTAGNLLLKMIDGP -PGITAFARSIGDNRTRLDRWETALNTAIPGDLRDTSTPAALGGGYRALLAGDVLSPPQRQ -QLEDWMRGNET--SSMRAGLPADWTSADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -RADDPKAANPLIGEL-------- ->[subseq from] class A beta-lactamase n=1 Tax=Microbispora sp. CSR-4 TaxID=2592813 RepID=UPI0011C83F0B ---DVAAALRALEASFKGRIGAYAIDTATGKTI-GYRAGERFPLLSTFKAVAAGAVLARTT --DRELTRKVVHWTADEVKSNSPETGKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -RGLTRYFRTLKDPVSRLDRWETDLNIWSPKERRDTTTPASAARDLRGLTTGGVLGAKDRS -RLIGWLRDNTTGDARIRAGLPKTWIVGDKTGTGGYGTANDIAVIWPANAAPIIMAIYTNR -RAADGATADSVVARTATLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kocuria sp. 257 TaxID=2021970 RepID=UPI0010104031 ---DMASKIRELEHELDGEIGVYAFDTSTGACF-GYRDQQRFLFCSVSKVLVAATVLNRAS -QDPTLLERRVSITREDILAYAPVTSQHLEDGMTVEELCAAALTVSDNTASNLLMEQCGGP -EAVTAFVRSTGDVTTRLDRIEPDLNEA--SGVLDTTTPAAFSETLNRLTLGDALTASGRD -KLVGWMKESTTGAEQIRAGLPEGTLTGDKTGSGTHGESNDVAVIWPQQGAPVIMSVFTKS -HRTDTVGQKAAIAGTAEAVFE-- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3D0L606_ALCFA ------QAAQQAESSLQARVGLAVLDTADGQRW-HYRADERFPMASTSKALICAALLARGQ ----GAMKTAWLVQQEAIQSYSPTTEKMVGEYVPAAQLCAITMRNSDNTAANGVLEMLGGP -AAVTSFVRTVGDSVTRLDRNEPTLNEARPGDPRDTTTPQAMVQTLQNLVLGDALEPHARE -RLIAWLRNNKVGGPLLRAGVPEDWTMADRTGAGGFGTRGVVAVIWPPKRAPLIAAVYVTE -TEAPMEDSNTAIAMIGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. lk TaxID=2201272 RepID=UPI000EAFCD0F ----LAEELAQIEIQAQGRLGLYVIDTSSGATA-GYRSDERFPMCSTFKTLLAARVLYLAQ -KGQIELWRKRYFSPSELVPWSPVTEKRAGANMTPLELCEAAVVFSDNTAANVLLDATGGP -AALTAWLAEIGDKTTRLDRREPQLNTAIAGDERDTTTPAAMAQTLQTLQRGDVIEGFGRA -FLRQWLIESRTGDKRLRAGMPTDWKFGGKTGSGENGTACDNLVVWPPQSSPILVTAYLTG -SKLDGPGRDAVLAKAGEAVKR-- ->[subseq from] Beta-lactamase n=2 Tax=Lapillicoccus jejuensis TaxID=402171 RepID=A0A542DWC9_9MICO ---STDRAFAALERTHDATLGVTAVDTGTGRTV-SWRPGTRFPFASTNKTFIAAAVLDRSS ---EADLDVVVRYTRADLLAYAPITSRFVDTGMTVRELLDAALRFSDNTAANLLVERVGGP -AAVQAWLRAHGDRVTRVDRVEPGLNEALPGDPRDTTTPAQFAQDVRDVVLGSDLALADRT -LLRDLMLGCTTGDGTVRAGVDPAWPVADKTGTGEYGVRDDVAVVYPAGRAPVVVTVFTRQ -DAPDATPADALVAAATRVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SB3404 TaxID=2711219 RepID=UPI0013EB7C4B ---ALSRRFRALESEYGARLGVYARDTDTGATV-AYRAAERFPMCSVFKAPAVGAVLRDLD -RDGEFLAKRVHYTQWLVRKYAPVTGKNLANGLTVGELCAAAVGESDNAAANLLLRELGGP -TAVTRFCRSLGDDTTRLDRWEPELNSSEPWRISDTTTPGAIGATFGRLLVGRALPRRDRE -RLTGWLVANTTNTDRFRAGLPEGWVSADKTGGGDYGVANDVGVVFPPGRGPLVLAVLSTT -YAAEGPQHDAIVARAVKLVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D000075 ---RAQSELAALDKASGGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Aureimonas sp. Leaf454 TaxID=1736381 RepID=A0A0Q6BM52_9RHIZ ---------ERIEAQVGGRLGVSIRDLQTGASF-SHRGSERFPMASTFKAFACAHLLALAD -AGTIDPGRREPIRAGDLQTYSPVTRNHVGDGLSLSALCEATTRTSDNTAANLILTATGGP -AALTAFLRSIGDDTTRLDRFEPDLNDVGPGDDRDTTSPDAAIASLQKLVLGDVLSANSRR -QLESWLAANAVGGPLLRASLPEGWRIADRTGAGEYGTRGIIAVIWPKAKGPILAAVYLTG -TKLSIDQRNGVIAELGAAMVE-- ->[subseq from] Beta-lactamase n=1 Tax=Actinosynnema pretiosum TaxID=42197 RepID=A0A290Z8G0_9PSEU -------AFAALEQRFDARLGVYALDTGSGRVV-AHRADERFAYASTFKALAFGALLAERS ---VADLDERVTFTREELVTYSPITEGRVDSGMTLREVADAAVRYSDNTAGNLLLRELGGP -AAFERALRAIGDTTTSPARVETELNEAVPGDLRDTSTPQALAADLRRYAVADVLPDDRRE -LLVSTMRANTTGDEVIRAGVPQGWVVADKTGSAGYGGRNDIAVLWPPDRAPIVLAVLSGK -ATADAVHDNALLAEATRAVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. KC13 TaxID=2711220 RepID=UPI0013EC26E7 -------SIAALEQTHQRRLGVWAKNMRTGRVI-EHRADERFPMLSTFKTLLTAAILRDLP ---ARTLQQRLTWDAADVVVNSPVTSVTTRNGLTVAQLAEATMTRSDNTAANELLHLIGGP -AGVTRFARSLGDTVSRLDRWEPDLNSAIPGDPRDTTSPRAIAQTYTKLVLGDALDRGDRD -QLITWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS -DDPTAAPLDKPLEDIAATVCA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI000F56F92A ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDRWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonadaceae bacterium KCTC 52780 TaxID=2172047 RepID=UPI000E0D6505 ---------------ASARFGFAAVDTASGRSV-VHDADSRYAMCSTFKWTLAAAILAEAE -AGRLQLDALIPFGEADLLGHAPVVRENIGAGLPVERLCAAIVEVSDNSAANLLLRRIGGP -QALTAFIRANGDDVTRLDRYEGALNSNLPNDPRDTTTPAAMVRLMERLLVGDALTPASRT -RLLGWMERSTTGLDRLRAGLPSDWRVGDKTGTGANGAHNDVAVAWPPARPPLLVASFISA -AQASGDACNAAHAAAGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Segeticoccus rhizosphaerae TaxID=1104777 RepID=UPI0012650F1A ----------------------------------SFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Roseomonas oryzicola TaxID=535904 RepID=UPI00143A9F80 ----LPGEFARIERSQGGRLGVAVLDTGGRRAA-EHRGGDRFPMASTFKMLLGGAVLARID -AGQDSLERRIRFGRGDLVTYSPATEGQAGGEMTVAALLEAMMTLSDNTAANLLLSAIGGP -EGLTAFLRRHGDAVTRLDRMEPALNEGTPGDPRDTTSPAAMLATMRALTLGEALSAPSRA -RLVWLMEGNRVSGSLFRARLPQGWRIGDRSGAGGFNTRGIAAVIWPSGGAPLLVTAYLTE -PQRTLAARDAVLAEVGGAIFAAy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075B1E54 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D0060E6 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A0J5WTR8_BURCE ---AAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTAFRLDRWEPELNLAAPGDERDTSTPVAMVDMLQRLLLGNTLQEPQRT -QLTEWMTGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPLVMAVSFTQ -PQADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=A0A561BU07_9ACTN -----HDQLLALERKYGARLGVYAVATGTGRTL-AHRADERFAFCSTFKGLAAAGVLHHNP ---LTHLDTVVTYTTDDLMKSSVITRQHVRTGMTLRQLCDAAVRYSDGTAGNLLLRELGGP -AALTAYLRTLGDQVTRMDRYEPHIVTAIPGDPRDTTTPRAIGTTYQNLVVGKALAPEKQA -HLRDLLERNATGRRRIRAGLPKSWTVADKTGTGDYGTTNDIALTWPPQAPPLLIAILSSK -PQEQAPSTSALLAEAATYT---- ->[subseq from] Beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=A0A379CPC3_PLESH ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKHDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia diazotrophica TaxID=667676 RepID=A0A1H6U2Y8_9BURK ----AHERFEQLEARSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLAVAAILKRSI -AERALLDTHIRYGEMDLVANSPVTKRHVSEGMSMGEICAAALQYSDNTAANLLLTALGGS -EVLNEFARSIGDTWFDLVRREPELNDAVPGDMRDTTTPRAMMRDMQKILLDDVLEPPQRE -KLKAWLLGNATGERRIRAAVRSGWPVADKTGSGDYGTANDVAVVYSPAAA-FVVAVYFTG -VTKETPPQDEVVDEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium lablabi TaxID=722472 RepID=UPI0009A7B8F9 -------ALAAYERDTGGRIGVYAENLSTGAKI-AWRAEQRFVMCSTFKASLAALMLARVD -RGEDRLEDMVAYGRKDILDYAPVAKQNLAHGMSVSDMCKAVVELSDNTCANLLLARAGGP -EALTAFWRSTGDTLSRLDHNEPELNRSPPGNPHDTTTPSAMAGNLRRFLLGAVLTPPSRE -HLTEWMVGCKTGNNRLRGGLPRDWKVGDKTGNNGKDASGDIAIAWPKSGGPVLVCAYTQG -GSPTPQQFEAVFKEVGAMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EsD8 TaxID=1301088 RepID=UPI0005C92EB7 ---RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES -QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP -TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLMDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas sp. NML140781 TaxID=2480812 RepID=A0A4Q8LNE8_9GAMM ------RDFAALEQVSGGRLGVTLLEVGTGRRM-GRRQDERFPMCSTFKALLAAHVLSLAD -AGALSLDERLPIRQAQLLSWAPESERHVGKDLTVRDLCRAAVTNSDNTAANLLLARAGGP -PALTAFLRKQGDAVTRSDRYEPAMNGFALDDPRDTTSPAAVAASLARFAVGDGLSKASRA -QYADWLIDNQTGDDCLRAGLGKRWRVGDKTGNNGRDTRNDLAVLWPLGGTPWVLVALLQG -ARVDADQRDAVLARVGALA---- ->[subseq from] class A beta-lactamase n=1 Tax=Jiangella muralis TaxID=702383 RepID=UPI00069E1511 ---AVAAALTALEGDYAARLGVYAIDTGTGRTI-EHRPDERFAFASTHKMLSAAAVLLATE ---PADLEQLIEVDAAEVVGWSPVTEPAVGAGLTLLEVIQAAVTVSDNTAANLLFEQVGGP -DGLEAAVRGFGDETTSFDRIEPDLSDWVPGETRDTTTPRAMAANVRGLLLGDLLAEEDRT -LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR -LDPEAESDPALIAAATEVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000759C44F ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000753B60F ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLLMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium marinum TaxID=1781 RepID=A0A2Z5YG60_MYCMR ---DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLFQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A3N8Q4R1_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFVRASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA -RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas thiooxydans TaxID=363952 RepID=UPI0007C562CC ----LSDELAALEVQARGRFGLYVLDTVSGAEA-GWRGDERFPMCSTFKTLLAARVLYLAQ -RDEIRLWRKLYYAPSEVVAWSPISEKWAGANMTVQELCEAMVLVSDNTAANVLLEASGGP -AALTQWLRELGDGTSRLDRNEPSLNTALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDKRVRAGMPGDWTVGGKTGSGERGTACDTLIVWPTAQAPLLVTAYLTG -SPLDGAGREAVLARAGEAIK--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoalteromonas denitrificans TaxID=43656 RepID=UPI000B89CB3A ----IIKKIEEQERQLGARIGVSIYDVTDNKLW-HYNGNTRFPLMSTFKVLACAKLLFDVE -KGLQSFDTSTVITKNSLIEWSPVTKNMIGEKISLKQACSATMSMSDNTAANIVLNGIKGP -KVLTRFMRSIGDDVTRLDRIEPDLNEALDGDKRDTTTPNAMVKSLHTLLFGDALSQASKT -QLKQWMIDNKVTGKLLRKVLPQNWSIADRSGSGGYGSRGITAVVWSDKRTPLIISIYLTQ -TEASFSQRNKAIANIGKEIFTVy ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. AG1037 TaxID=2183990 RepID=UPI000E0B13A9 ----TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAALAASS ---PADLDEVVHYDRGDLLSHVPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV -AGVTRWLRGLGDTTTDVSRTEPDLNTALPGDRRDTTTPAQSAADLRAVLLGDALDADDRS -LLRNAMLGTTTGATTIRAGVDPSWTVADKTGTASYGVRNDVGVVTPPGRDPIVLVVMTAH -GTVDAEPSDALVADATRIAIAH- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=Q2QCK2_SALTM --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKAELVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVKNQVTGNLLRSVMPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus TaxID=1827 RepID=UPI000569115E ---RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES -QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP -TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLTDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] Beta-lactamase n=2 Tax=Tardiphaga sp. OK246 TaxID=1855307 RepID=A0A239NXU4_9BRAD ------AALLAYERDTGGRIGVYAENLKTGAKI-AWRANERFVMCSTFKASLAACVLARID -RGEDKPDQMISYAAADLLDYAPVARDNLAKGLSVADMCKAIVELSDNTCANMLLARVGGP -AALTAFWTKTGDSVSRLDHNEPLLNRSRPGNPQDTTTPTAMAGNVKRFVTGNVLTAASRD -QLTDWMVNCKTGDKRLRAGLPKSWKIGDKTGNNGKDAAGDIAVTWPKPDQPVVIAAYTQG -GTPTAPQLETVFTAIGEMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0007556269 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Pseudoalteromonas TaxID=194690 RepID=UPI0005AA1CF4 ---TISKKIEEIESQLDARIGVSIYDVTDNKLW-DYNGDTRFPLMSTFKTLACAKLLVDVE -KGLQSFNTSSVITKSSLVKWSPVTKKHVGELFTLKQACSAAMIMSDNTATNIVLASIKGP -KELTRFMRSIGDDVTRLDRVEPYLNEALDGDKRDTTTPTAMVKSLHTLLFGDILSQDSKV -QLKQWMIDNKVTGSLFRSVLPEGWSIADRSGAGGYGSRGITAVVWSDKRSPLIISIYLTQ -TDASFALRNKAIANIGKEIF--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB6 TaxID=2015568 RepID=A0A257CF86_9BURK ----LATLCAGLESQHGGRIGVCLMETRTGRLW-QYRADERFAMCSTFKLLLAAAVLTQVD -AGRLSLQQTVAVRKTDLVPYAPVMEGLLGTRVPLGMLCEATVGVSDNAAANVLLPWVGGP -AGLTRLLRAWGDAVTRLDRNEPELNSNLPGDARDTTSPAAFARTVASVVHGSTLSSQSRQ -QLQLWLRGASTGMNRLRAPWPADWQAGDKTGTGPRGAVNDVAVAWPPGQPPLVLAVFMGG -STATSDNLNAAHAAVARWAM--- ->[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria xinjiangensis TaxID=402600 RepID=UPI000B7CAFEE ------DALAELERKFGARLGVYAT--GAGGTV-EHRADERFAFCSTFKGLATAAVLHRNP ---MSHLDTVVTYTEAELMKSSAITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLRDVGGP -AELTRYLRELGDTETRMDRVEPDITSATPGDPRDTATPRSLGTDYRRLVLGDALPPEKRD -FLTDLLERSVTGAKRVRAGVPQGSRVASKTGTGSYGTVNDIAIVWPPGGEPLLIAVMSSK -DAADAGYDEALVAEAAAYVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenaceae bacterium 429 TaxID=2562948 RepID=A0A4S1E6S5_9BURK ------QKAAAIEEQLQARVGVAVIDTASGQSW-LYKADERFPMASTAKTLVCAALLQQGE ----PLLHSPVLLQPDDIQTYAPVTKELVGQTMSAFQLCEITLRSSDNTAVNLVLNVVGGP -SAVTSFLRRIGDQVTRLDRLEPEVNEAKPGDERDTTTPAAMAATMRALLLDSALNPTMRA -QLVEWLKANDVAGPLLRAGVPSDWVVADRSGSAEYGTRGVAAVMWPTQHAPIVAAVYITE -TDAPIEARNAAIASIGQAIAE-- ->[subseq from] Beta-lactamase n=2 Tax=Roseivivax TaxID=93682 RepID=X7F2J9_9RHOB ------DLVRETEQALGARVGLVVRDSGSNWSW-DHRADERFLMNSTLKAPLCGAVLAQVD -AGAIDLDEALPVRPEDMVDYAPVTENEVGGTMSVDDLCLAALDMSDNAATNIVIDRLGGP -QEVTTFLRGIGDEVTRLDRKEPDVNTFDPADPRDTTTPEAMTRTLEALLAGDALSAGSRA -RLTAWMTPGGVTGAHFRAHVPRDWRIADKSGAGDF-TRNIVAMITPPGAEPYFVAIYLSG -ADADFETRNAAVIALSAAVVD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KJ38_9BACT ------SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio barjaei TaxID=1676683 RepID=A0A1J4R8E1_9VIBR ---TLDESIASIEQRISGRIGVSVFDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD -SGELDKNTLAPITSDKLIPWSPVTEKMVGSSITINKACEATMETSDNTAANIVLHSIGGP -QALTEFLRLNQDDVTRLDRIEPELNQAVSGDIRDTTTPNAMNTTLHRLLFKGALNQDSKN -QLMAWMQGNTVSDSLLRSILPQGWSIADRSGAGANGSRGFTGVLWADNRNPLIISIYLTQ -TDLSMSERNQIINEIGGLIFQTy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A5P2JZ93_9BURK ---RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. D16Q20 TaxID=1855660 RepID=UPI000993056F ------TELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQSDVLEWAPIASQHVAEGMTVSQLCDATIRYSDNTGANLLIAQLGGP -KQTEKYVRSLGDNVSRMDRTEEELN--IPDGDLDTSTPLQLVTNLRRLVLDEGLDPQGRD -LLTDWLKRNTTGDQSVRAGVPAGWAVADKTGGGFKSETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTKSKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. EsD8 TaxID=1301088 RepID=N1M7B0_9NOCA ---RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES -QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP -TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLMDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=UPI0009532D08 ---TLADTVERVESRLGARIGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD -AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIARLGGP -QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPVAMTETLRGLLLGDVLSRSSRG -QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD -VDADSQTRNRALQDVGRAAM--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia steynii TaxID=1245441 RepID=A0A4R0X6V1_9BURK ----ARERFEQLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERSLLDERVRYGEADLVANSPVTRRHVGEGMTIGELSVAALQHSDNTAAKLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGSQQRE -QLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVVAVYFTG -VMKQTLPRDEVVVEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Afipia sp. GAS231 TaxID=1882747 RepID=UPI000B87702E --------LAAYERDTGGRIGVYAENLSTGAKI-AWRAEERFVMCSTFKASLAAFVLARVD -NAEDRLEDMVAYGAKDLLDYAPVAKQNLAQGMSVADMCKAIVELSDNTCANLLLARVGGP -AALTEFWSRTGDAVSRLDHNEPELNRSPPGDPRDTTTPSAMAGNLRRFLLGTVLTPSSRE -HLTQWMVDCKTGNNRLRGGLPADWKIGDKTGNNGKDASGDIAIAWPKSGGPVLVTAYTQG -GSPTPPQLETVFKEIGAMVAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ICBB 8177 TaxID=563922 RepID=A0A2U3C791_9ACTN --nAVEARLLDLEARHSARLGVFARNTATGRTV-AYRARELFPICSAHKVISVAALLKDLD -VHGDFLAERITYTVKDTTDYAPVTGTHLAHGMTVAQLCAAAIEYSDNAASNLIVRQLGSP -QAVTRFCRSIGDRTTRLDRWEPALNSAEPWRVTDTTSPVAVARTYARLVLGGVLSRAHRN -LLTGWMLADTTSGQRFRAGLPRDWRLADKTGTGDYGTANDVGIAWTPDGTPVVLSVLSTK -HDPKAQADEPLIAEVAAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces rimosus subsp. pseudoverticillatus TaxID=1464079 RepID=A0A0M8RGF8_STRRM -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIQDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAITWTPDGAPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Aeromicrobium TaxID=2633570 RepID=A0A5F2ETI9_9ACTN ----TRGDFAAIETSYDTRLGVFALDTGTGRRV-SWRSSERFPFASTIKAPLAAVVLDRTS ---RRDLSRTITYDASDLVPHSPVTEKHVADGLPLRDVIDAALRFSDNTAANLLFDQIGGP -AGLDRELDRIGDRVTNPVRTEPDLNTATPGDVRDTTTPKALATTVGTYVVGRALPRHDRD -LLRTTMTNNTTGDALIRAGVPDGWVVADRTGGASHGVRTAVAVAFPPGRSPVLIAVMSRR -DQADDEYDDGVVADATRVAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. QIA-37 TaxID=1561223 RepID=UPI0007A0E94B ---------TALEDWYGARIGVYAVDLDSLRTV-EHRADERFSMCSTFKTYAAARILQLSD -AGAADLDTKITIARDDVVVDSPITRDAIGSSMPLGDICAAALTHSDNTAGNIMLRTIGGP -AAITTFARSIGDTHSRLDRWEPDLNTAIPADPRDTTTPKALCTGYRRILTADVLATPARD -RLLTWMKSNVTSSKRFRAGLPPGWTSADKTGAGDYGSTNDAGLLIGPNGQRVVAVVMTRS -RDHDAPPFNEAIAGAIRV----- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=A0A059MVZ9_9NOCA ---RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES -QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP -TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLTDWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio mediterranei TaxID=689 RepID=A0A241TD39_9VIBR ---TLDESIASIEQRISGRIGVSVLDSSNQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD -SGELDKNALASITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIILHSIGGP -QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNRGSKN -QLIAWMQGNTVSDSLLRSILPQGWSIADRSGAGANGSRGFTGAIWADNRKPMIISIYLTQ -TDLSMSERNQIINEIGGLIFQTy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007C7E2D6 ---SAQAQLAGLEKALDGRLGVFAWDSTKNVVL-AHRATERFPVNSTFKALLAGQALALDA -HPPGLMNKYLAVSAGDIIKHAPVTEKFVGRNMTVAQLCQATVETSDNPAANILMRELGGP -ESLTSFMRSIGDNTFRLDRYEPELNTAIPGDLRDTSTPEAMVRSLHTLTLGGGLRPPQRE -QLRNWLLGTVTGSRRIQAGVPPGWRVAGKTGSGAYGAAHDLGLIWPPDRPPIVLAIYSHL -NEPNAAWREEIIAAAARIV---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium stomatepiae TaxID=470076 RepID=UPI0013D83C5D ----FYDRLAELERQYNAYIGLFATHLGSGRTL-AHRDDDPFAMCSTFKAYAAARVLQKTQ -RGELDLQQRVFIDPAALLPNSPVTAPQAGNTMPLAQLCAAALQHSDNAAANLLLAEVGGP -PAITDFARSIGDERTRLDRWEVELNAAIPGDPRDTSTPRALGAGIQNLLTGTVLGEAQRS -QLERWMRDNVT--SSMRAGLPPGWTTADKTGNGDYGSTNDIGMVYGPSGQRVSLSVMTRS -QSRDADALRPLIAEVTKSVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mannheimia haemolytica TaxID=75985 RepID=UPI000BAAA59F ---TFQQTLANLEQQYQARIGVYVWDTETGHSL-SYRADERFAYASTFKALLAGAVLQSLP ---EKDLNRTISYSQKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKVYDKSGAGKYGVRNDIAVVRIPNRKPIVMAIMSTQ -FTK-------------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea zeae TaxID=1642303 RepID=A0A5S4GL93_9ACTN ---QVTKELRALEASFKGRIGAYAIDTGTGRTI-AYRSGESFPLLSTFKAVACAAALNKAR -TEPGLMAKVVHWTSAEVKENSPATEKHVRDGMTVSALCEAAITLSDNTAGNMVLKQIGGP -AGLTRYFRTLKDPVSRLDRWETELNDWTPKEKRDTTTPAAMGRDLRALTTGSALTAKDRK -TLNAWLKANQTGDARIRAGLPPSWTVGDKTGANPAGLTNDVAVVWPGKSAPIILSIYTNR -SASDADASNQAIAKTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Falsirhodobacter sp. alg1 TaxID=1472418 RepID=UPI00078690CF ----LLPTVAQIEARLDGRIGLSLIETGSGRSW-TYRKDERFPMNSTVKVPICATVLARRD -AGKLSLSDILRVNQEDILSYAPVTEKTVGAGMSLADLCLAAIDMSDNTAANMLVDHIGGP -QAVTDFLRGTGDELSRLDRREPELNNFLSGDPRDTTTPAAMTETLRRLLLGNALSSESGK -QLAEWMSIGGVTGNLLRADAPEGWIILDKSGGGSH-TRNIVAVVIPEGGSPWIVTIFISD -VDADSSTRNAALQQIGSAVM--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0003710E33 ---STTARLRELERVHGARVGAFAYNVATGVAV-RHRADERFPMLSTFKTLAAAAVLRDLD -RDGEVLDKVIHYTGADCVSDSPITNTNIANGLSVARLCDAAIGDSDNTAANLLLRELGGP -GTVTRFARSLGDGVTRLDRWEPELNSAEPGRVTDTTSPAAIARDYARLVLGNVLEPGDRE -RLTGWLLNCRTSGTRFRAGLPVEWTVADKTGGGSYASCNDVGIAWTPEGAPVVLAVLTTK -PDGDAAGDHPLVRDAAKALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf89 TaxID=1736245 RepID=UPI0006FE6BB5 -----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE -AGRERLDRRLAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAALGGP -AALTAYGRDLGDPVTRLDRTEPDLNSAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA -RLEGWMTASRTGTKRLRAGLPADWGVGDKTGSGAYSTANVVALLRPPARAPLVAAIYLTG -SDTTSEARDAAHAAIGRVIAATy ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MBT27 TaxID=1488356 RepID=UPI0014236504 ---DVSDALRQLEAAHDVRIGAYALDTVTGRTV-SYRGNESFPSLSTFKAMACAAVLDRAR -HEPGLLDKVVHWKASDEVANSPVTKGQGGKGMTVAELCRAAITQSDNTAGNMVLHQIGGP -QGMTRYYRSLGDPVSRLDRWEPELNDWQPGEHRDTTAPASMGRDLAKTSLGCGLAPADRD -TLNTWLRATVTGGERIRAGLPKDWTVGDKTGTTDYGSANDIAVAWPKSGHPVIIAVYTNH -AVAQAPADNAVIASTASTLV--- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. AF50-3 TaxID=2293021 RepID=A0A3R6N380_9CLOT --------FQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLALNLKEYATGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. D16Q14 TaxID=1855658 RepID=UPI0009934B78 ------TELASLEKDFGGRIGVYALDTGSGATL-GHRPNERFLMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQSDVLEWAPIASQHVAEGMTVSQLCDATIRYSDNTGANLLITQLGGP -KQTEKYVRSLGDNVSRMDRTEEELN--IPDGDLDTSTPLQLVTNLRRLVLDEGLDPQGRD -LLTDWLKRNTTGDQSVRAGVPAGWAVADKTGGGFKSETNDIAVIWPPGRAPIVVAVLTVP -DDPKSTKSKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Paracoccus marinus TaxID=288426 RepID=UPI00103D331E ---DLRTTISGWEQRLEGRIGVAVHDSGAGTRW-GYRQDERFLMNSTVKVPLCAAVLARVE -GGDLALDEILAVTQDDIVTHAPVTERHVGGGMTIADLCLATIDQSDNTAANLLFERLGGP -SEVTKFLRGIGDEVSRSDRLEPALNVLAKGDDRDTTTPAAMANTLEVLLTGDALPPAARA -QLADWMRPGGVTGALLRPSVPAGWDVADKSGSGDN-SRTLSAMVTPPGGAPVFISISVSD -TTADMSARNAAVADIGGAVMK-- ->[subseq from] Beta-lactamase n=15 Tax=Bacteria TaxID=2 RepID=A0A127STA5_9BACT ------SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas terrae TaxID=673548 RepID=UPI00083376A9 ---ALSDELAAVEAQAQGRLGLHALDTVSGAEA-GWRSDERFPMCSTFKLLLAARVLYLAQ -KGEISLWRKIYYSPSELVPYSPATEKRAGADMTPQELCEAAVVLSDNTAANVLLDATGGP -AGLTAWLREMDDKVTRLDRNEPTLNEALAGDERDTTTPRAMLHTMQNLLLGDVFEGFGRA -LLQQWLVDSRTGDRRLRAGMPGSWKIGGKTGTGNNGTACDAIIVWPPQSEPVLVTAYLTG -SKLGAAAQEAALARAGEAVRR-- ->[subseq from] Beta-lactamase n=1 Tax=Plesiomonas shigelloides 302-73 TaxID=1315976 RepID=R8AQR8_PLESH ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKILSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=1 Tax=Nocardioides sp. Leaf285 TaxID=1736322 RepID=A0A0S9QC09_9ACTN ------AAFAALEERYAARVGVVAIDTATGETL-AHRGDERFPYASTVKALAAAVLLDRTT ---PSDLERVVPVRRTDLVDYSPVVEQRVGRGLTLGAAAEAAVRVSDNTAGNIVLEAIGGP -DGLRRALRGLGDRVTDPRRTEPTLNRFEPGDDRDTTTPRALATTLRTLAVDDTLAPADRR -LLLRWMSGNETGDTLVRAGVPDDWAVADKSGSGAYAARNDVAVVTPPGRAPVVVAVLTRS -EDVDAVARDALVAAAAGVVAR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Paucibacter sp. KBW04 TaxID=2153361 RepID=A0A3N7E0Q6_9BURK ---ELLARIEALQKRSGGRIGLFALNSGSRAQI-AFNADQRFAFCSSFKLLLAAAVLARVD -AGQLSLDKPIRFGSNDIVAHAPITSARLVNGMSVGELCEAIVTVSDNPAANLLFPLVGGP -PGLTRFLRELGDQHTRSDRIELALNTNLVGDERDTTTPAAFVASMEALLLGNRLSEEAVH -LLLGWMVGSTTGLQRLRAGLPEGWRAGDKTGSGANGAVNDVAIFWKPEQAPLLMAVFMTG -SEQSVDELNAIHAELAGLVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter sp. DsW_063 TaxID=1514894 RepID=A0A252C307_9PROT -------AIGTYERESGGHIGVYAENLATGGKL-LWRADERFVMCSTFKASLAACVLRRVE -RGQEKLDRNVAYTKADVPDYAPVAKEKLARGMTVAEMCRAAVEQSDNTCATLLLSSVGGP -AALTAFWRSIGDTQTRLDDPEPYLNRTPLGGVRDTTTPEAMAKVLQRVVLGDVLSDSSRA -LLTGWLVGCQTGGNRLRAGLPKTWRVGDKTGNNAKDAAGDIAVLWPKPDAPIIVAVYTRG -GAPTDAQLTAAFSGVGALVAK-- ->[subseq from] Beta-lactamase n=2 Tax=Halomonas taeanensis TaxID=284577 RepID=A0A1G7P806_9GAMM --sDLNQRLAELERAADDRVGVALMNVTTGAVA-SHRGHERFLFNSTGKFFIAAAVLARVD -EGSETLDRRIVVEKGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPDLNTDHEGDERDTTTPLAMMVTLRTLLLGDALSPSSRH -QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIGWPGDRGAVIAVAYTLM -PSATKTQRDDTIAAVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas denitrificans DSM 6059 TaxID=1123010 RepID=A0A1I1NV19_9GAMM ----IIKKIEEQERQLGARIGVSIYDVTDNKLW-HYNGNTRFPLMSTFKVLACAKLLFDVE -KGLQSFDTSTVITKNSLIEWSPVTKNMIGEKISLKQACSATMSMSDNTAANIVLNGIKGP -KVLTRFMRSIGDDVTRLDRIEPDLNEALDGDKRDTTTPNAMVKSLHTLLFGDALSQASKT -QLKQWMIDNKVTGKLLRKVLPQNWSIADRSGSGGYGSRGITAVVWSDKRTPLIISIYLTQ -TEASFSQRNKAIANIGKEIFTVy ->[subseq from] Beta-lactamase n=1 Tax=Afipia sp. GAS231 TaxID=1882747 RepID=A0A1G9ZS41_9BRAD --------LAAYERDTGGRIGVYAENLSTGAKI-AWRAEERFVMCSTFKASLAAFVLARVD -NAEDRLEDMVAYGAKDLLDYAPVAKQNLAQGMSVADMCKAIVELSDNTCANLLLARVGGP -AALTEFWSRTGDAVSRLDHNEPELNRSPPGDPRDTTTPSAMAGNLRRFLLGTVLTPSSRE -HLTQWMVDCKTGNNRLRGGLPADWKIGDKTGNNGKDASGDIAIAWPKSGGPVLVTAYTQG -GSPTPPQLETVFKEIGAMVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=Q9REJ2_VIBHA ---------PRLKKHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMASQTTRIEHACEAAMLMSDNTAANIVLRSIGGP -RGVTTFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILDEy ->[subseq from] Beta-lactamase n=1 Tax=Salinisphaera sp. Q1T1-3 TaxID=2321229 RepID=A0A3A5JCB6_9GAMM -----VARLAALEKANGGRLGVAILDTAAGHRY-GYRADERFLMCSTFKLLLVAAVLQRVD -RGLERLDRRVVFDQSAILDWAPVTGLNVGAPMNIAELCEAATLMSDNTAANLLLDTLGGP -AGFTAFVRTLGDERTRLDHREPLNNR--QEGAQDTTTPAAMLGAMRSVLLGETLSDAARQ -RLLGWLRLNQTGAQALRAGLPANWSVGDKTGSASN-ANNDIAIVWPPGRKPLLVTAYYVA -ETQDTSARKRVLADVGRIVA--- ->[subseq from] Beta-lactamase n=9 Tax=Clostridiales TaxID=186802 RepID=A0A0E2H6V7_9FIRM --------FQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLALNLKEYATGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075F0715 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000925DF2B ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDNTGSGDYGT----------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. Root135 TaxID=1736457 RepID=A0A0T1WK35_9MYCO ----VADGIVALENRFDAFVGVWAADLDNGRQV-ANRADDPFAMCSTFKAYAAGRVLQKDQ -AGALHLTDAVTIEAGDLVENSPITETRVGQNMTIGELCEATLQRSDNTAGNWLLRIIGGP -SAVTTFARTIGDDRTRLDRWETDVNSAVPGDPRDTSSPRALGAGYQRLLTGDVLDAPHRD -QLERWMRGNQT--SSLRAGLPEGWTSADKTGGGSYGSTNDVGVVYGPDGRRALLSIMTRS -RTPDAHDLRSLVAEVTTLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075F74E4 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLLLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A4S3HUL4_BURCE ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobium sp. Leo121 TaxID=1571195 RepID=A0A4Q7G4U6_9BRAD --------FEAYERETGGRIGLYAEDVATGAKV-TWRSGERFVMCSTFKASLAACVLARID -RGEDQLENVVRYRAADLLHHAPAARQNLASGMSVADMCKAVVELSDNTCANLLLARIGGP -AALTAFWRDTGDTVSRLDHYELELNRSPPGDPHDTTTPAAMAGNLRHFVLGEVLSPASRE -RLTGWMLNCKTGNNRLRGGLPKDWKIGDKTGNNGKDAAGDIAVVWPRKGGPVLISAYTQG -GSPTAQQLEAVFVAIGQM----- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=A0A1B4I4F3_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPGDERDTSTPVEMADTLQRLLLGNTLQEPQRA -QLTAWMAGGARGTTGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Rhizobium sp. AAP116 TaxID=1523429 RepID=A0A0N1AJV1_9RHIZ ------AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD ----AVLEQTTRITKADLRPHSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP -AEVTAFLRGIGDATTRLDRYEPEVNEAKPGDPRDTTTPQAMAQTLQVLLVGDALAPAARD -QLEAWMAANAVAGGLLRAKLPSGWTIADRGGAGGHGTRGVVALLRPPQGAPLVIAIYMDG -RKHPLKTRDAAIAEIGEAVFEEf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium dioxanotrophicus TaxID=482462 RepID=A0A1Y0C6R4_9MYCO ------DQIAGLEKRNNALIGVFAANLDSDRTV-AHRADETFAVCSTFKGYAAGRVLQLVD -RGQLALDTRIFIDPSAIVANSPVTEERTGADMSIGELCQAALQHSDNTAGNLLLKMIDGP -PGITAFARSIGDDRTRLDRWETALNSAIPGDPRDTSTPAALGAGYRALLAGDVLSPPQRQ -QLEDWMRGNET--SSLRAGLPAGWTSADKTGSGDYGSTNDVGLAYGPDGQRLLLAVMTRS -RADDPKA---------------- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LFA6_STEMA ------ADLAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSIPRNDRNEPDVNLFVKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -TSVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SC45_9BACT ------SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces himastatinicus TaxID=998084 RepID=UPI000A309EAA ---DVTRQLRALEEEYAARLGVFAFDPATGATV-AYRAEERFPMCSVFKALAAAAVLRDLD -RDGEFLAKRVHYTEEFVRKYAPVTGKNIAGGLTVEQLCAAAVSESDNAAGNLLLHDLGGP -TAITRFCRSLGDGTTRLDRWEPELNTAEPWRDTDTTSPGAIGKTFARLVLGRALTPEDRK -RLTGWLVANTTNIERFRKGLPADWILADKTGGGQYGVANDVGVVWPPERTPLVLSVLSTK -YDPQGPTDNPLVARAAALVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium iranicum TaxID=912594 RepID=A0A178LTZ4_9MYCO ----IEERIEALAKRHNAQIGLYAVNLDNEESL-GYRDSEVFAMCSTFKAYAAAAVLERAQ -QGRLALSDTVPIEATDIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRALGGP -PAITEFARSIGDDRSRLDRWEVELNSAVPGDPRDTSTPRALGVGYRAMLTGDVLQPAGRQ -QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRMLLAIMTRS -AVPDAASLRPLIGELATLVL--- ->[subseq from] Beta-lactamase n=2 Tax=Rhodobacteraceae TaxID=31989 RepID=A0A327LW87_9RHOB --eTLEQTVDQIETKLDGRIGISLIDTGSDFTW-SHRQDERFLMNSTVKVPLCGAVLARVD -AGTLSLSDQLPVTQGDIQSYAPVTEQRVGQSMSIGELCMAAIDMSDNTAANLLIDHLGGP -QAITQFFRNTGDIESRLDRQEPELNTFAPGDPRDTTTPVASTDTLHTLLLGDALSDRSRK -QLADWMSHGGVTGQLLRAEAPAEWQIYDKSGSGSH-NRNLVVMVTPESRAPWVVTIFLSD -MDEDFETLNAALQDISRAVT--- ->[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A0G3YND6_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDRWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=A0A1Q9QST3_RHOSU ---TLADTVERVESRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLASRD -AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIAHLGGP -QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPAAMTETLRGLLLGDVLSRSSRG -QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD -VDADSQTRNRALQDVGRAAM--- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea fuscirosea TaxID=1291556 RepID=A0A2T0NBD4_9ACTN ---QVKKELRALEASFKGRIGAYAIDTASGRTL-AYRSGERFPLLSTFKAMACAAALHRAR -TQPGLMDKVVKWTAADLKPNSPTTEKHVKDGLTVAKLCRAAITLSDNTAGNMVLKQIGGP -AGLTRYFRTLKDPVSRLDRWETELNDWAPKDRRDTTTPAAIARDLRAVTTGGALSAKDRE -RLNGWLIATETGGARIRAGLPKSWTVGDKTGTNTIGAGNDIAVAWPAGRAPIILAVYTNR -EGSGAVTNDAAIARAATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. THAF12 TaxID=2587849 RepID=A0A5P9HFQ6_9GAMM ---DLERQLGELERSADDRVGVALMNVASGAVA-SHRGHERFLFNSTGKCFIAAAVLSRVD -EGRETLDRRIVIDEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPALNTDHAGDERDTTTPLAMMATLRTLLLGDALSPSSRH -QLASWMIEGKVGDARLRAGLPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTFM -PNATGAERDETIAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia sp. NBAIMH1 TaxID=2600320 RepID=UPI0011B78FF1 ---AVAESFEELESRYDARLGVYAVDTGTGDEV-AWRDEERFAYTSTIKAIAAGALLDQVG ---LEGLETEVPIQESDMVPHAPVTENHVGQTLTLGEIAEAAVTVSDNPAANYLFDEFGGP -AEFDAVLEELGDDVTEVVRREPDLNEAAPGDDRDTTTPRAISENLQEYLFGTTLNDEEKS -QLRQWMIDSETGDTLIRADLPSEWTIGDKSGGGGYGSRGNIAAIWPAEGDPIVIAVLSSR -DEPDAEHDDRLIAEAAEAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. Amel2xB2 TaxID=1305829 RepID=UPI000DBACCA9 ---EVARGLRKLERQHSARVGVFARNMRTGTTL-VHRADERFPLCSTWKPLAVAAVLAGRG -GGEALLDARVRYSEDDLEEHSPVTGEHLDHGMTLGQLCDAAVRQSDNTAANLLLRQLDGP -AGVTRFCRSLDDRVTRLDRWETELNSAEPGRTEDTTSPRAVARTYARLVLGDALEPPQRR -RLTDWLKRNTTGDDSLRAGLPEGWSIGEKTGSGAYGTNNDVGVAWAGDRTPVILAVYTTK -HSAGAEPDYPLIAAATRLL---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium wolinskyi TaxID=59750 RepID=A0A1X2EWI3_9MYCO ----VDDQIGELERRHNAVIGIHAVNLDSNRIV-SHRADDMFAMCSTFKAYAAGRVLQMVG -RDQLSLDNRVFVDPDAIVMNSPITEPRAGSEMTLGELCAAALQRSDNTAGNLLLKTIDGP -AGITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRALLVGDALSPPQRR -QLEDWMRANQT--SSMRAGLPAGWTTADKTGSGDYGSTNDVGVAYGPAGQRLLLAMMTRS -QTDDPKAANPLIGELT------- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=UPI0009947446 ----KSTELASLEKDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAVLHRRL -SEPGLLDKRIQYTQADIMEWAPIASQHVDEGMTIAELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRIEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD -LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVTVLAIP -EDPKSTKGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012618419 ---ALSAQVKSVENTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSVQQEPMFVSIYLTQ -TEASFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=BLAF_MYCFO ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRLDEMFAMCSTFKGYAAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTEARAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTAAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI000464B05B -----GERFAGLESRRGVRLGVFAVN-GRGDRV-GYRQDERFAFASSFKALACGALLREHP -LDTGYFDRVVRYAGEELVANSPVTRDHVNSGMTVDELCLAAITRSDNTAGNQLLKLLGGP -PALTEFLRSIGDEKTRSDRWEIELNTAVPGDDRDTTTPAALAADYRALTVGNILGPAERD -RLNSWLVMNTTGGQRIRAGVPADWRVGDKTGTGEYGSAVDVAVAWTGRGEPVVIALLSTK -PDRHAEADDELLAEATRIVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A1V4AA68_9ACTN ------GRLGALEKEYGARLGVFALDTASGATV-SYRADERFPMCSVFKALAAAAVLRDVD -RHCEFLTRRIHYTEEFVTDYIPVTGRNIAHGMTGAQLCAAAVSESDNGAGNLLLRELGGP -AAITRFCRSVGDGTTRLDRWEPELNSAEPWRAEDTTSPRAVGKTFGRLLVGGALAPDDRE -RLQDWLIANTTNTERFRKGLPADWVLADKTGGGEYGVANDVGVVRPPGRAPLVLSILSTK -YDPQGPTDNPLVARAAALVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00F21D ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0006C7C6B5 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIAMAVSYTQ -PRADAAPRNDVIASAARIVAN-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=unclassified Vibrio TaxID=2614977 RepID=UPI001372CDDD ---RVEQEVRSIEEQLSARIGVAVFNTETDEHW-NYRGEERFPLTSTFKTIACAKLLHDSE -QGDIDPLSKVKIEENDLVTYSPIIEQYVGQEITLDDACQATMSTSDNTAANMIIKAVGGT -ESITSFIRAMGDEVTRLDRIEPDLNQGLLNDLRDTTTPNAMVITLHELLFGSVLSESSQQ -KLLMWMINNQVTDNLLRSVLPNGWGIGDRSGAGGFGARSITAIVWSKTQSPIIISIYIAQ -TEASIEQRNQAIVKIGKAIFDNy ->[subseq from] class A beta-lactamase n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=UPI0011A82A7F -----HDQLLALERKYGARLGVYAVATGTGRTL-AHRADERFAFCSTFKGLAAAGVLHHNP ---LTHLDTVVTYTTDDLMKSSVITRQHVRTGMTLRQLCDAAVRYSDGTAGNLLLRELGGP -AALTAYLRTLGDQVTRMDRYEPHIVTAIPGDPRDTTTPRAIGTTYQNLVVGKALAPEKQA -HLRDLLERNATGRRRIRAGLPKSWTVADKTGTGDYGTTNDIALTWPPQAPPLLIAILSSK -PQEQAPSTSALLAEAATYT---- ->[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium damselae subsp. damselae TaxID=85581 RepID=A0A5N4FP62_PHODD ---ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPVAIVETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTQHKPMVMSIYIQQ -SSASMDERNKAIAIIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5PI30_9ACTN ----VAAALTALEDDYAARLGVYAIDTGSGQIV-EHRPDERFAFASTHKMLSAAAVLQATE ---PADLDQLIEVDAAEVVGWSPVTEPAAGVGLTLLEIIEAAITLSDNTAANLLFEQLGGP -DGLEAAVRGFGDTTTSFDRIEPGLSDWVPGEERDTTTPRAMAGNVQDLLLGDLLADEDRT -LLHDTMRANTTGDELIRAGVPDGWVVADKTGSATHGGRNDVAVIEPPGAAPIVLAVYSNR -LDPEAESDPALIAAATEIVVDE- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=B9BHK2_9BURK ---RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSLTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0014281F3E --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLVGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=UPI0005C12D8D ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPDNRA -TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANEAIAEIGKQLF--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=A0A1W2FGS2_9PSEU ---TVTGKLRELEKRHNARLGLFATDTGTGRTV-LHRADEIFPMCSTFKTIAAAAILRKDR --DGTLLGKVITYTQSDVDKWGPETGKNLANGMTVSALCEATITYSDNCAANLLLRELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRITDTTSPRAIGQSYARLTLGHALNSNDSD -QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR -KDPTGGADEPLLAKTAELVAATf ->[subseq from] Beta-lactamase n=1 Tax=Oleispira antarctica RB-8 TaxID=698738 RepID=R4YSQ0_OLEAN ------EKIKQVESELSARVGVSVYDVSSKQLW-DYDGDVRFPLMSTFKTLACAKLLSDVD -NGDQSFDSSVVIKDSSLITWSPVTKKHVGESFSLKQACSAAMIMSDNTAANIVLDGINGP -SALTKFMRSIGDEVTRLDRIEPYLNEAIDGDVRDTTTPNAIVKSLHELLFGNALSESSKN -QLKMWMMDNKVSDSLLRSSLPNDWSIADRSGAGGYGSRGITAVVWSGKRTPLIISIYLTQ -TDASFDERNKAIAGIGKEIFTFy ->[subseq from] Beta-lactamase class A n=1 Tax=Klenkia taihuensis TaxID=1225127 RepID=A0A1I1QXC5_9ACTN --------VDALEATYGARVGVWALDTGTGRVV-EHRAGERFAHASTLKLLLTGLLLDRVS ---DAELDAVVPIAADDVLEYAPVTSQHVGTGLPLREVMAAATTVSDNTAANLLVEQLGGP -AQVQAALRELGNPTTRVDRVEPELNEATPGDPRDTSTPADLGASVQQLVLGDVLAPDRRA -LLQQWLRDSTTGDAAIRAGVPDGWEVGDKTGSGGYGTRNDVGVVEPDDGAPLVVVLLTDR -GVPDADTDDALLADATRLVVDQ- ->[subseq from] Beta-lactamase class A n=2 Tax=Rhizobium sp. RU33A TaxID=1907413 RepID=A0A1N6SY11_9RHIZ ------AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD ----AVLEQTTRITKADLRPYSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP -AEVTGFLRGIGDATTRLDRYEPEVNEAKPGDPRDTTTPQAMAQTLQGLLVGDALAPAARD -QLDAWMTANAVADGLLRSKLPKSWTIADRSGAGGHGTRGVIAVVRPPKGAPLVVAIYMDG -KAHPLKTRDAAIAEIGEAVFADf ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis excentricus (strain ATCC 15261 / DSM 4724 / VKM B-1370 / CB 48) TaxID=573065 RepID=E8RLQ3_ASTEC -----GQRLMEIQKRHGGRVGVSVRDTAADGSL-NINSSERFALCSTFKWVLATAVLKAVD -DGKLSVTQEIRYSKADLLDHSPVTEKHVPKGLTVGDLCSAAVAVSDNAAANLLLPLIGGP -AGLTAFVRGLGDMVTRLDRNEPELNSNIEGDERDTTTPDAMSSLLRNVFTGAVLQPKSLS -LLRDWMVATVTGPDMSPAGVPKGWTVGHKTGRGANGAVNDVAVIWPSGELPIFLSIYTTG -GTLDDKARNAVVADITRLVID-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. E136 TaxID=1834125 RepID=A0A1A2MDL4_9MYCO ---QLAGRLAEMERSHNALIGVFAVNLDTRRTV-AHRAQDPFSLCSTFKTYAAARVLQRAE -RGELALTDRVTVEQGDIVPNSPVTGEHIGQTMTLAELCQAALQQSDNAAGNLLLRTIGGP -SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEALGGGYRSLITGNVLGEPQRR -QLDDWMRANRT--STVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT -AAPDVPNDRQMVGDVGSMLVA-- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. ND22Bw TaxID=2054178 RepID=A0A2P7PBE4_9GAMM ---DLERQLGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTGKFFIAAAVLARVD -EGRETLDRRIVIEEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPELNTDHAGDERDTTTPLAMMATLRILLLGDALSPSSRH -QLAAWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTLM -PNATGAERDDTVAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T13 TaxID=2696565 RepID=UPI001412686C ---EAAERFAQLEQRFDARLGLFAVDTGSGEVV-THRADERFAFASTYKALAAAAVLDRTT ---DAELDGVVTWEAGDLVDHSPVTGDHVATGLPLRAVAEAAITVSDNTAANLLLERLGGP -QALEQELRALGDGATEVDSTEPEVNDHVPGETQDTSTPRAMATSLRAYAVGDALEAGDRE -QLVEWLRANTTGGEQVRAGVPAGWVVGDKTGHAGYGNQNDIAVVWPADRAPWVLTVLTDR -TGVDDESDDALLAEATRVVVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=UPI0005AB0F31 ---TLADTVERVESRLGARIGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD -AGDLSLQTELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLLAHLGGP -QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDTTTPAAMTEALRGLLLGDVLSRSSRG -QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD -VDADSQTRNRALQDVGRAAM--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Methylobacterium TaxID=2615210 RepID=A0A5C8VMQ5_9RHIZ ------GRIGAVEVRLGGRVGVAFHD-ATGVFL-GHRADEAFALCSTFKVLAAAAILARVA -AGRETLDRRIAYGADDLQSYAPVTRSRAGGGMTVDGLCAAAIVRSDNTAANLLLDALGGT -AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPAAITRTLDRCLLGDALAPPHRA -RLEAWMVACETGGAKLRAGLPPAWPVGDKTGSGDNATSNVVAILHPPGRAPILAGVFLTG -SEAPPAARDAAHAEIGRILAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A2 TaxID=236253 RepID=UPI00084BE6F2 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGA -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMSVLGGP -QAVTAFARECGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDVLREPQRA -QLTEWMVGGARGATGIAAGVSPGWRVADKAGTGGFGTTTDVAVLWPPSHAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1LTY7_MYCCH ---------TALEDWYGARIGVYAVDLDSLRTV-EHRADERFSMCSTFKTYAAARILQLSD -AGAADLDTKIPIARDDVVVDSPITRDAIGSSMSLGDICAAAMMHSDNTAGNIVLRTIGGP -AAITAFARSIGDTHSRLDRWEPDLNTAIPADPRDTTTPKALCTGYRRILTADVLATPARD -RLLTWMKSNVTSSKRFRAGLPPDWTSADKTGAGDYGSTNDAGLLIGPDGQRVVAVVMTRS -RDHDAPPFNEAIAGAIRV----- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. ZAC14D2_NAIMI4_6 TaxID=2072406 RepID=A0A3Q8F9B4_9GAMM -------DFAALEKASGGRLGVTVLDTGSGRRLgGHRQDERFPMCSTFKSMLVAHILSLAD -AGRLSLDTRVPIAEQDLLSYAPVARRHVGKDLSVRDLCRGTLTTSDNTAANLLLGVNGGP -AALTAFLRAQGDPITRNDRYEPDMNRFAKGDPRDTTSPAAMAASLARFAVGAGLLPPSRL -QFADWLVDNQTGDACLRAGLGPRWRVGDKTGSNGEDTRNDIAVLWPRGGTPWVITAYLQG -ASVDEAQRAAVLARVGAL----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2L1J139_KLEPN ------------ERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardiaceae bacterium YIM PH 21723 TaxID=2340915 RepID=A0A419HJ22_9PSEU ------PRLTELEKKYGARLGVYAEVIGTSRML-EFRADDRFAFCSTFKALATAALLRAHP ---LSYLDTRVRFAESDLMKHAPITRSHVDTGMTLRELADAAIRFSDGTAGNVILREIGGP -GMLTQYARSLGDDVTRMDHIEPVITAAVPGDPHDTSSPRAFGTSLRKIVAGDALPEDRRA -FLRDLLERTETGKDRIRAGVPAGWRVADKTGTGDYGTLNDIAIVWPPDRPPLLISIMSSK -PAQDAEYQPALLADAARYVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0011ADFEA1 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLLLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alteromonas facilis TaxID=2048004 RepID=UPI000C28E48B ----LSEKLRAIENETGGILGVAVLDTESQHLW-HYNGDLRFPMMSTFKTLACAKMLHDHD -KSLIDSATEYPVIKAELVVWSPITKDLVGQSISLFDACEATMLTSDNTAANIALKQIGGP -PAVTQFLRTYGDPTTRIDRYEPELNQAVAHDPRDTTTPKAMTETLSTLLLGTTLSKTSAQ -QLKQWMQNNTISDALLRSVLPSAWQIADRTGAGENGSRGITAIIWNSSRPPIILSIYLTQ -TQLSLSERNAVIAEIGNAVFHHy ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. KH9 TaxID=1855324 RepID=UPI000B7D9C3B ----LTVALADVEARHGVRLGLHALDTAQGRTV-SHRADERFAFCSTVKPLAAAAVLAS-- -RGVGGLDEAVPVTADDLVTYSPVAETRVGVGMTWRELGDAAVRYSDNTAGNLLLRGAGGP -EGLTAWLRGVGDDVTRSDRWEPDLNAFTPGDERDTSTPRALAGTYGALVVGEVLAPPERD -VLTDWLVRNTTGDALVRAAARPGWTVGDKTGSGAYGTRNDVAVVWPPDGAAVVLAICTDQ -AVPDADTVDAPLAEAARVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Z8XPW5_ECOLX ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANETIAEIGKQLF--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea polychroma TaxID=46176 RepID=A0A438MBD6_9ACTN ----VKKELRALEKAFNGRIGAYAVDTATGKTV-TYRAGERFPLLSTFKAFACAAVLHKAR -TDPGLMNKVMHWTADELLEHSPVTEKHVKDGLTVAQLCEATITVSDNTAGNLILKEIGGP -AGLTKYFRSLKDAISRLDRYEPGLNDWTPKDKRDTTTPAAIARDLRVLTIGNALHAKDRE -QFNAWLIATKTGDARIRAGLPKTWTIGDKTGTNSTGGGNDIAVIWPEKGAPLIMAIYTNR -SP-GLATDDKTIAKTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium OK006 TaxID=1592326 RepID=A0A0N0MWU7_9ACTN ----------------------------------RHRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLASGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAPDSPLVAAAASLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. WAC 06783 TaxID=2203211 RepID=A0A429I3M8_9ACTN -----VRRLRALEGEHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIDTGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGGYGTRNEAAIAWTPDGAPVLLTALTHK -PSPTAPGDTPLIIKLATV----- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. C35 TaxID=2126993 RepID=UPI000D699E54 ----AQERFQKLEQRSEGRLGVAALNTADGSYV-GYRESERFPMCSTFKLVATAWVLKRSM -AERGLLDERVRFGEADLVANSPITRRHVREGMSIGELCAAALQYSDNTAANLLLTALGGS -EVLNEFARGIGDEWFNLVRVETEVNASVPGDMRDTTSPRAMMLDVQKFLLDEVLGLQQRE -QLKTWMLGNTTGAARIRAAVPSGWRVADKTGSGDYGTANDVAVVYPPAAEPLVLAVYFTG -VTRETLPRDEIVVEAARVVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=UPI0013E8F23D ---ALSPHFAALEQEFAGRLGVYALDTGSGTAL-GNRQSERFLMCSTVKVFIVSAILTRRR -TEPGLLEKRIHYTNADILDWAPVTPAHIADGMTVEELCAAAVSHSDNTAANLLIAELGGP -EETEKFVRSIGDSTTNTDRTETDLD--IPDGDKDTSTPEQLVSNLRTLVLGDALDREGRD -KLIGWMKANTTGDQSIRAGVPHGWEVGDKTGSGSRGESNDIAVIWPPNRAPILLAVLTAP -DDPTSTKGKLTIAQATRQAI--- ->[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=A0A2K8GRJ1_ATLHE -----TAFLQQQEKQLNAHIGMAVVNAQGESVF-GYRQDERFPLTSTFKTLACAALLERLQ -KDGGSLDQQVTIQPDELLDYAPITKNYLAPALSLRTLCAAAVSYSDNTAGNRILAYLGGP -QAITQFMRRLGDNVTRLDRTEPTLNEAMPGDARDTSSPKSMAAGLQKILTSNTLTPANRA -TLDSWMREDKVGDALLRATLPQGWSIADKTGAGGHGSRAIIAAVYPPQQAPFYVAIYITR -TEATMPMTNTAIAQIGERLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia mexicana TaxID=279262 RepID=UPI00082D8CF4 ---AAEEHFAALERKYDARLGVYAISTGTAVSL-AYRADDRFAFCSTFKTLAAAAVLQRHP ---MSYLDTVVRYTREDVNSISPVAQDHIETGLTIRELCDAAIRFSDGTAGNLLMRDIGGP -EQLTAYLRSLGDTVGRMDQYEPELNSDPPGDPRDTITPRALAADYQQVVLRGALPPEKQA -LLKDWLQRSATGAQTIRAGVPAGWTVANKTGHGDFGRANDVAVVWPPDGAPLILAIMTDR -TGFDAAPPYPMIADAAAYLSKAf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia (strain MC0-3) TaxID=406425 RepID=B1K308_BURCC ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARESGDTTFRLDHWEPELNKAAPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARAATGIAAAVPPGWRVADKAGTGGYGTTTDIAVQWPPSRAPIVMAVSFTQ -PDAAAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51961_SCH5331710 TaxID=1834105 RepID=A0A1A0RQ74_9MYCO ---QLAGRLAEMERSRNALIGVFAVNLDTGRTV-AHRAQDPFSLCSTFKTYAAARVLQRAE -RGELALTDRVTVEQGDIVPNSPVTGEHIGQMMTLAELCQAALQQSDNAAGNLLLRTIGGP -SGVTDFARSIGDQRTRLDRWEIELNAAVPGDPRDTTTPEALGDGYRSLITGNVLGEPQRR -QLDDWMRANRT--SSVRPVLPPGWTIADKTGSGDYASTNDVGVAFGPAGERLLLAIMTRT -AAPDVPNDRQMVGDVGSMLVA-- ->[subseq from] Beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=A0A2P1VMM6_PLESH ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPDAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=12 Tax=Enterobacteriaceae TaxID=543 RepID=A0A3L4MDJ0_ECOLX ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANETIAEIGKQLF--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4NID0_9ACTN ---QVKKDLRGLEVSFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLRKAR -TKPGLMNRLIKWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQVGGP -KGLTRYFRTLKDATSRMDRWHPELNDWTPKDKRDTTTPAAIGRDLRVLTVGRALHAKDRR -QLLAWLLANKTGGERIRAGLPKSWTVADKTGTNSFGGGNDIAVVWPKRGAPVIMSIYTNR -TK-GLPTDNKTIAKTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI00126248E8 ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHSLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSVFDTf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. Soil538 TaxID=1736391 RepID=A0A0Q9JCP5_9MYCO -------DLKGIEHRHRARIGAYAVDLGTAATV-EHRADERFAMCSTFKAYAAGRVLQLVD -QSRLDLRTPIPVNAADIVANSPVTEQRVGATMALAEVCEAALTRSDNAAGNLLLRTIGGP -GGVTAFARTLGDEQTRLDRWETELNSAIPGDARDTTTPRGLCWGYRQLLTGTALSPSARA -TLDGWMRANVTSGPRFRAAVPTGWTTADKTGAGDYGSTNDAGLILGPTGQRVMAVVLTRS -IDKDTPPLNAAISDTVRLILDSf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0008414043 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDRWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPTRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia GG4 TaxID=1009846 RepID=J7J7M3_BURCE ---AAQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCMALLQSNDKGAGNLLMGVLGGP -QAVTSFAHESGDPAFRLDRWEPELNQAAPGDLRDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAGVPPGWRVADKTGAGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PSADAAARADVVASAAHIAT--- ->[subseq from] Beta-lactamase n=2 Tax=Tatlockia micdadei TaxID=451 RepID=A0A098GIU2_TATMI ---SIDKKLAKLESSSGGRIGVYAINTTNNTHL-EYRADERFPMGCTSKVMGVAAVLKKSM -KDNLLLSKKVTYTKNDLTNWNPITEKNLDTGMSVKELCAAAISYSDNTAMNLLLKQLGGL -EGMNAFARTIDDDSFRQTHGWPEAMSGGQNNTDDSSTPAAMATSLKKLAFTDALAKPQRE -LLLTWLKANTTGDARIRAGVPKGWLVGDKTGTGYYGTTNDIAIIWPPKCDPIVMAVYYTS -NNKNASKREDIVASTTRIILDE- ->[subseq from] Beta-lactamase n=1 Tax=Kosakonia arachidis TaxID=551989 RepID=A0A1I6ZR91_9ENTR ----LAEVVRLQEQQLGARIGVAVVDSARGKTV-SYRGDERFPLNSTHKALLCGALLSQVD -KGELALTETTQFPRSALVAYSPVTEKFIAPAINWQQLCSAAVSYSDNTAANLLAQKLGGP -VAITHYLQILGDSVTRLDRAEPELNSAIPGDVRDTTTPLAVSRTLQKLTLGTALKPGSRA -QLIQWMREDKVADMLLRSTLPAGWVIADKTGAGDFGSRSIISVVWPKNSTPRIVVIYITN -TKATLKQSNVAIARLGKEIF--- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia mexicana TaxID=279262 RepID=A0A370GJP1_9NOCA ---AAEEHFAALERKYDARLGVYAISTGTAVSL-AYRADDRFAFCSTFKTLAAAAVLQRHP ---MSYLDTVVRYTREDVNSISPVAQDHIETGLTIRELCDAAIRFSDGTAGNLLMRDIGGP -EQLTAYLRSLGDTVGRMDQYEPELNSDPPGDPRDTITPRALAADYQQVVLRGALPPEKQA -LLKDWLQRSATGAQTIRAGVPAGWTVANKTGHGDFGRANDVAVVWPPDGAPLILAIMTDR -TGFDAAPPYPMIADAAAYLSKAf ->[subseq from] Class A beta-lactamase n=1 Tax=Comamonas sp. TaxID=34028 RepID=A0A5N7WCV6_COMSP --kTLGEELAALEVQAQGRLGLHVLDTVSGAEA-GWRSEERFPMCSTFKTLLAARVLYLAQ -KDEIRLWRKLYYAPSEVVAWSPVSEKRAGADMTVQQLCEAMVLVSDNTAANVLLDASGGP -AALTQWLRELGDGTTRLDRNEPSLNSALPGDERDTTTPQAMVQSLQKLLLGDVLEGYARA -LLQQWLVDSRTGDRRVRAGMPGDWKAGGKTGSGERGTACDTLIVWPTEQAPLLVTAYLTG -SALDGAGREAVMARAGEAIK--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. LS-044 TaxID=1459967 RepID=A0A4S5DDR4_9BURK ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLLLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase class C n=1 Tax=Burkholderia sp. NFACC38-1 TaxID=1566268 RepID=A0A1H9ZXM8_9BURK ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0007ED8A83 ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLTDVD -AGKLALKDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007553D47 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLSRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacteraceae bacterium 0127_4 TaxID=2686094 RepID=UPI001315C956 ------QRFAAIEARIGGRVGVAAWNTGTDAWL-GHRRNEAFAMCSTFKWALTAAVLHTAQ -RGGPQLNEIVCYNQSDMLSHAPVTSQHLERGMTVEELCAAAVITSDNPAANLLLELQFGP -EGFTRFLRANGDGVTRLDRTELALNENLPGDPRDTTTPDAMARTLKRFLLEDVLNAASRE -KLTGWMETSTTGLSRLRAGLPAGWRVGDKTGTSTHNATNDVAIAWPPGRAPIIITSYLSE -SMVELDARNAAHAEIARIIAGEw ->[subseq from] class A beta-lactamase n=2 Tax=unclassified Vibrio TaxID=2614977 RepID=UPI0013737AAD ---QLTQSVKDIESDWQGRIGVYAYDIYGSFTF-GYREQERFPLCSSFKSLLAAAILQKSQ -NQLLNLDTSIDFSERDLEFWSPITEENHAEGMSIGQLAQAALQYSDNGATNILLERIGGP -KGMNTFMKSIGDEDFRLDRWELELNTAIPGDERDTSTPKSMATSIGKLSFGNVLSASHQE -LFHDWLIGNTTGDNRIRAAVPKQWQVGDKTGTCGYGAASDVAVIWREKASPLVIAIYTHK -SEPSAKHSDKIIAEVAKETLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Cellulomonas sp. KH9 TaxID=1855324 RepID=A0A1I3ZN96_9CELL ----LTVALADVEARHGVRLGLHALDTAQGRTV-SHRADERFAFCSTVKPLAAAAVLAS-- -RGVGGLDEAVPVTADDLVTYSPVAETRVGVGMTWRELGDAAVRYSDNTAGNLLLRGAGGP -EGLTAWLRGVGDDVTRSDRWEPDLNAFTPGDERDTSTPRALAGTYGALVVGEVLAPPERD -VLTDWLVRNTTGDALVRAAARPGWTVGDKTGSGAYGTRNDVAVVWPPDGAAVVLAICTDQ -AVPDADTVDAPLAEAARVVLD-- ->[subseq from] Beta-lactamase n=2 Tax=Bradyrhizobium diazoefficiens TaxID=1355477 RepID=A0A0E4BP52_9BRAD -------ELEAYERESGGRIGLYAENLATGAKI-AWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMLPYGQADLLSYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRIDHNEPEVNKSAPGDPHDTTTPAAMAGNLRRLVTGEALSPASRA -QLTEWLVGCKTGANRLRGGLPASWTIGDKTGNNGKDASGDIAVAWPKDTAPILIAAYTQG -GSPADRG---------------- ->[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. SLBN-172 TaxID=1813332 RepID=A0A542MV05_9ACTN -------SIAALEQKHQRHLGVWAKNMRTGRVV-EHRADERFPMLSTFKTLLVAAILRDLP ---VRTLQQRLTWEATDVVVNSPVTSLTVRNGLTVAQLAEATMTRSDNTAANELLHLIGGP -AGITSFARSLGDTVSRLDRWEPDLNSAIPGDPRDTTSPRAIARTYTKLVLGDALGGADRD -QLLTWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS -DDPAAPPLDAPLADIAATVC--- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) TaxID=452652 RepID=E4N3R1_KITSK ---QIVDRLRQLERIHGARLGVFAHDTGTGTTV-HHRADERFPLCSTFKPLAVAAVLRDGH -----DLAAAVHYTDRDVADYAPVTGRT--RALTVAELCAAAIEFSDNTAANLLLRRLGGP -TAVTRLCRSLGDPVTRLDRWEPDLNSAEPDRETDTTTPSALARTFARLTLGDALPQPQRA -RLTAWLRACTTGAHRLRAGLPPSWTLADKTGTGAHGTANDLALAWPPHRPPLVLAVLSTK -PAPTATPDEPLLAATARLLAATf ->[subseq from] Beta-lactamase n=2 Tax=Actinosynnema mirum TaxID=40567 RepID=C6WEM9_ACTMD -------AFAALEQRFDARLGVYALDTGSGRVV-AHRADERFAYASTFKALAFGALLAERS ---VADLDERITFTGEELVTYSPITEGKVDTGMTLREVADAAVRHSDNTAGNLLLRELGGP -AAFERALRAIGDTTTSPARVETELNEAVPGDPRDTSTPEALAADLRRYAVADVLADDRRE -LLVSTMRANTTGDEAIRAGVPRGWVVADKTGSARYGGRNDIAVLWPPDRAPIVLAVLSGK -ATADAEHDDALLAEATRAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Roseivivax sediminis TaxID=936889 RepID=A0A1I1SV82_9RHOB ---TLARTVGQIEGRLEARVGIALVDTGSGATW-SHRPDERFLMNSTAKVPICALVLAQRD -EGDISLSDALTVRESDLLSYAPVTSEHVGESMSMSELCLAALDMSDNTAANLVLDRAGGP -EAVTDLFRQAGDPVSRLDRREPDLNAFTPGDPRDTTTPAAMAATLRELLLGETLTVASRE -QLAAWMSHGAVTQDLLRSHAPAGWEIFDKSGSGDQ-TRNIVALVSPSNGAPWLVTIFISD -ADTDFATRNAALKDLSAAVM--- ->[subseq from] class A beta-lactamase n=1 Tax=Leifsonia aquatica TaxID=144185 RepID=UPI00046844F2 ----TQGAFSALERTHAATLGVTAIDTGTGRTV-AYRGGERFPFASSNKTFIAAATLQASS ---DADLDTVVHYTSADLLAYAPITSRFVDTGMTVRELLDAMLRFSDNTAANLLVARLGGP -DAVEAWLRGIGDRTTNVDRIEPDLNEALPGDARDTTTPAQFAADLRAVLLGSTLETKDRT -LLRNTMLDCTTGDGTIRAGVDPAWPVADKTGTGEYGVRDDIAVVYPAGRAPIVIVTMSRH -ATADAASDDALLAAATKVAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Lentzea terrae TaxID=2200761 RepID=UPI000DD37879 ------EALFELEKKYDARLGVYAAG---VSTI-EHRADERFAFCSTFKGLATAAVLHRNP ---MQHLDTLVRYTEADLMKSSTKTRPNVQTGMTLKDLCDAAVRFSDGTAGNLLLKDLGGP -TQLTGYLRELGDTETRMDRTEPAITEATPGDPRDTTTPRAIGTAYQKIVLGDALEPAKRD -FLTDLLTRSVTGAKRIRAGVPQDWRIADKTGTGDYGTLNDIAIAWPPNREPIVISIMSSK -SQGDAKYDEALIAEAAAYVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2T3IE66_9GAMM ---ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium diernhoferi TaxID=1801 RepID=A0A1Q4HAL3_9MYCO ----FEEQVRELEARYNAFIGLYAVNLESGATV-ASRADEAFALCSTFKTYAAAAVLQRVA -AGELSLEQRLFVDPAALLPNSPVTGENAGHEMTLAELSQAALQRSDNLAANLLLETLGGP -SAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTSTPRALATGYRNLLAGEALPAAQRE -LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYGTTNDSGVAYGPDGTRLLLTIMTRT -QSADAEGLRPLIGELAAL----- ->[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9N1Q5_9BURK ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Tabrizicola sp. DJC TaxID=2305252 RepID=A0A411YXW3_9RHOB --qRLFETIAEIEQRLNARVGILVRDSGSDWSI-SHRSNERFLMTSTFKPMLCGAVLKQAE -VGKLDLDESVWIAAKDILDYAPVTKTMVGDTMTIDDLCFAALDMSDNTATNLLIDRIGGP -EEVTSFLRDIGDPVSRLDRREPELNTFAPGNPRDTTTPEAMAATLEVMLTGTALTQQSRE -QLTEWMSHGGVTGPLIRASTPADWQVADRSGSGNF-NRNIIAMVTPPDQAPYFISVFLSD -ADADFETRNGAVIELSQAVMD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000CD4DD07 ----ADTAFGELEQEFDARLGVYALDTGSGAEV-AHRADERFAVASTFKALAAGAVLDQYG ---LDGLNTLTAFDLDDLVSHSPVTERFAGDGMPLGDLAAAAVRQSDNTAANLLLEALGGP -SGFTEALRAVGDDVTRIDRWETELNDVPPGEERDTSTPRALSETLSTYLLGDVLDAQEKD -RLAEWMTTNTTSATLIPAGVPDSWIVADKSGGASYGIRNDIAVLWPEEGEPVLLSVLSNR -DEEADESDDALIARAATAALE-- ->[subseq from] UPI00143EDE5E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143EDE5E ----LDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES -QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP -TAVTAFARSLGDTVTTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLTGWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00058DE9F5 ----LSRELRALEGRFGARLGVFARNAVTGASV-RYRAGETFPICSTFKTLATAAVLRDLD -QNGEFLAKTIRYTAQEVEDYGPITGENLAHGMSVEALCAAAVSYSDNAAANLLLRELGGP -RAVTRFCRSLGDPITRLDRWEPELNSAEPWRTTDLTTPAEVGLDYGRLVLGKALPRGDRE -LLTGWLRGNTTGDARLRAGLPEDWTVADKTGTGEYGTTNDVGIAWTGDGTPLILSVLATQ -PDPEAPAVDALIAETARLLV--- ->[subseq from] Beta-lactamase n=1 Tax=Humibacter sp. WJ7-1 TaxID=2599293 RepID=A0A5B8M9M6_9MICO ---ALSSQLSQIETRFGARVGVDVLDTGAGTTF-GYRATERFALDSTSKVLTSGMVLSEAD ---DARLATVIHFGSSELQSYSPITSQHVDTGMTLSALVAAALQYSDNTAANLLYGELGGP -AAAQSRLRAWGDTITNLDRVEPDLNSAVPGDVRDTSTPGQMATALKALLIGDRLSAQRRA -FLRDTMLANTTGGPYIRAGVPSTWRVADKTGNGGYGSRNDVAVLYPPGASPIVLTVYTTR -STADAASDDGLIATVTRSVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora atroaurantiaca TaxID=285545 RepID=A0A561F1Q6_9ACTN --qTLYRQLKKLERDHSARLGVFARNMATGTTV-LYRADELFPICSVFKTLAAAAVLRDLD -QDGEFLARRIHYTQKDVTDYGPITGKNLANGMTVAQLCAAAVSDSDNAAGNILLRELGGP -TAITRFCRSIKDWTTRLDRWEPLLNSAEPWRISDTTSPRAIGTTYARLLLGDVLPPRDRE -QLTGWLIANTTNRGRFRAGLPVDWTLADKTGGGDYGVANDVGVVWPPDGPPIAMTVLTTT -LASTGPRDEPLVAKTATLLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID11385 TaxID=2706031 RepID=A0A6B2UQ84_9ACTN ---TLVSRFRALEGEYAARLGVFALDTATGRTV-SYRADERFPMCSVFKGLAAAAVLRDLD -REGEFLAVRVRYTAEFTRTYAPVTGENLANGMTVAQLCAAAVSFSDNAAGNLLLRALGGP -TAITRFCRSLGDPTTRLDRWEPELNSAEPWRDTDTTSPRAIGRTYARLVVGRALTPGDRE -KLTGWLVANTTDDERFGSGLPADWVLADKTGGGQYGVANDVGVVWPPDRAPLVLSVLSTK -YDPAGPTDNPLVARTAALVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1423905.2 TaxID=1856859 RepID=A0A1A3HL33_9MYCO ------GRIDELEDQYHAIVGVYARDLASGRAV-THRADDAFAMCSTFKVYAAARVLQKCE -RGELDLAQATFIDPAALQPNSPVTAPHAGDTMPLSLLCAAALQRSDNTAANLLLQAIGGP -PAITDFARSIGDDRSRLDRWEIELNTAIPGDPRDTSTPRALGGGIEKLLTGAVLASSQRS -QLETWMRGNVT--STMRAGLPPGWTTADKTGTGDYGSTNDIGVAYGPDGRRVLLAIMTRS -QAPNADALQTLIADVTRAVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. PA05 TaxID=2604466 RepID=A0A5D0QKH9_9ACTN ---DVKKELRALEASFKGRIGAYAIDTATGKTV-GYRSGERFPLLSTFKAPLCAAALHKAR -TEPGLMDKVVKWTADELKPNSPTTEKHVEDGLSVAKLCQAAITESDNTAANMVLKQIGGP -AGLTRYFRSLKDPISRLDRYETELNDWTPKERRDTTTPAAIARDLRLLTTGGALKAKDRE -QLNAWLIANKTGDARIRAGLPKSWKVGDKTGTNGIGGANDIAVVWPSSGAPIILAVYTNR -PVA--STDDAVVAKTATILA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9MG99_9BURK ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N9HP83_9PSEU ----YTTDFAALEKRFDARLGVFAVDVTTRRTV-GHREEERFAICSVFKGYAAGALLKANP -LSSGFFRKTIKFGTADLVDGSPVTSTRVQSGMTVAELCHAAITRSDNTAGNQMLKLLGGP -TKLTEFARSIGDPMTRLDRWETALNVVPRGTEQDTTTPSAIAKAYQMLVVGDALGAPERQ -QLKDWLVANTTGGERIRAGLPSGWVTGDKTGTGSFAAANDVAVTWPSPDKPIVIAVLTDK -TAEDAEYDSALLAEATKIAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. S2-17 TaxID=1990687 RepID=A0A2S2C3T0_9NOCA ----LDSRIAELEARHSTRIGVTAVDPTTGAVY-RHRGAERFALCSTFKTYAAAEVLRRTS -EGTSSLDKAVPVEASALVENSPVTAAAVGTSMTLAELAEAALTRSDNTAGNLLLTEIGGP -QAITSLARSIGDDTTRLDRWETELNTALRGDPRDTSTTDGLAEGYRALLLGDELEPTHRR -QLLDWLRASTTSDTRIRAGLPPGWSAADKTGTGRFGTANDAGVVWDREGNPLLLVILTDS -STEAAQPNSDAIAETTTAVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia metallica TaxID=488729 RepID=UPI000D1AE532 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA -QLTAWMAGGARGTTGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A103ZJQ2_BURCE ---AAQADLTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00050FEB44 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPHDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A142YWV2_9BURK ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRD -LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKETLPRDEVVVEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0004F750D1 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQAGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Rahnella TaxID=34037 RepID=D7PIH4_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKESE -VKKNLLTQHVGLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PEKDAK----------------- ->[subseq from] Beta-lactamase, putative n=1 Tax=Ricinus communis TaxID=3988 RepID=B9TH63_RICCO ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRD -LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKETLPRDEVVVEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6H4T4_9BACT --------------------------------------EERFPMCSTFKFLAAAAVLKRVD -HGKENLERFVRYGAKDILEYAPVTKAHLQDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -AGLTDFARSLGDQITRLDRKEPELNSAIPGDERDTTTPAAMCSNMQRLLVGELLSESSRH -QLEDWLQHNETGALMMRAAVPKTWSGGDKTGRCANGATSDIAIIRPPGRAPIIIAVYSIG -SKAPADDRAAAIAEVAHAIMK-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas neustonica TaxID=1840331 RepID=A0A558IYL0_9GAMM --qQVEQEARLIEVTLSGRIGVTVLDTKNGEYW-DYKGDERFPLTSTFKTIACAKLLYDSE -QGDINLNSTVKIKKTDLVTYSPVIEKYVGQAITLDDVCSATMKTSDNTAANIIINAVGGT -ESITDFVRHTGDEKTRLDRFEPDLNEGIPGDLRDTTTPKSIANTLNELLFGSTLSPMSQE -KLKTWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEHQSPIIISIYIAQ -TEVSMKERNEVIAKLGNSIFKVy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFF531F ---RAQSELASLDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea violacea TaxID=128104 RepID=A0A1G9QPU8_9PSEU ---TVTGKLRQLEKRHNARLGVFATDTGTGRTV-LHRADELFPMCSTFKTIAAAAILRKDR --DGTLLGKVITYTQAEVDKYGPETGKNLANGMTVSALCEATIIYSDNCAANLLLRELGGP -TAISRFSRSIGDPVTRLDRWEPELNSAEPGRITDTTSPRAIGQSYARLTLGHALNSNDSD -QLTKWLLANTTGGNRIRAGLPSAWRWGDKTGTGSYGTTNDVGIAFPAGRAPIVIAVLSTR -KDPTGGADEPLLARTAELVAATf ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=Q84EY2_ATLHE ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANEAIAAIGKQLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00075B1EF1 -----AQAAQVVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQYVAASQLCAITMRNSDNTAANGVLEMLGGP -EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQSLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVVAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000B7A8BDA ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARTSGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGDTLQEPQRA -RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000DD4B65A ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=2 Tax=Terribacillus aidingensis TaxID=586416 RepID=A0A285N7P6_9BACI ------DAFSQLEETYDARLGIFAIDTGSGETI-AYREDERFGFASTHKALSVGVLLLQNS ---VENLNKKISITSDDLVNYNPITEKNVNTQMTLKELSEASISYSDNAAANLIFAEIGGP -EGFEQGLRAVGDQVTDSSRIEPELNHVEPNQIQDTSTPKAMTESLRAFTLEDHLSSEKRQ -LLIKWLKGNTTGDTLIRAGVPSDWEVGDKSGAGSNGIRNDIAILWPPDKEPIVLSIMSSR -DKAGAEYDDALISKAAEEVI--- ->[subseq from] Class A beta-lactamase n=1 Tax=Amycolatopsis bartoniae TaxID=941986 RepID=A0A557Z878_9PSEU --------FADLEARFGAHLGVYALDTGSGRDV-AYHADQRFAYASTIKALATGAVLRKES -----DVDKMLTYSPAEVVSHSPVTGDR--TSVTLREAARAALQQSDNTAGNLLFRELGGP -QGLDAALHEVGDTTTHADRTEVTLNEAVPGDVRDTSTPRAMATSLRTFLLGDALPADARA -LLADWMRGNTTGATLIRAGLPAQWTVADKSGAGNYGTRNDIAVAWPPSGAPVVLAVMSTK -DAKDAAYDDGLVARAASVAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A1S1L517_9MYCO ----KSTELAALENDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYRQADVMEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRLEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD -LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albus (strain ATCC 21838 / DSM 41398 / FERM P-419 / JCM 4703 / NBRC 107858) TaxID=1081613 RepID=A0A0B5F4A0_STRA4 ----LSRELRALEGRFGARLGVFARNAVTGASV-RYRAGETFPICSTFKTLATAAVLRDLD -QNGEFLAKTIRYTAQEVEDYGPITGENLAHGMSVEALCAAAVSYSDNAAANLLLRELGGP -RAVTRFCRSLGDPITRLDRWEPELNSAEPWRTTDLTTPAEVGLDYGRLVLGKALPRGDRE -LLTGWLRGNTTGDARLRAGLPEDWTVADKTGTGEYGTTNDVGIAWTGDGTPLILSVLATQ -PDPEAPAVDALIAETARLLV--- ->[subseq from] class A beta-lactamase n=2 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI001261FFA5 ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AVLTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQDPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. FMUSA5-5 TaxID=2720023 RepID=UPI0014390D7C ---QVTKELRALEASFKGRIGAYAIDTATGKTV-GYRPGERFPLLSTFKAPLCAAALHRAR -TEPGLMEKVVKWTADDLKPNSPTTEKHVEDGLSVAKLCEATITESDNTAANMVLKQIGGP -AGLTTYFRSIKDPISRLDRYETELNDWTPKEKRDTTTPAAIARDLRALTTGDALNAKDRE -QLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNGIGGANDIAVAWPNSGAPIILAVYTHR -TV--AATDDSVVAKTATILA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QC20_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTGPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG -ASVDYDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. E7m48 TaxID=1561197 RepID=UPI0006D3B116 ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKETLPRDEVVVEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI0007EBE46D ----IDDQLAELERRDNVLIGLYAANLQSGRRI-TRRPDEMFAMCSTFKGYAAARVLQMAE -HGEISLENRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAVTAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGEALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDAENLRPLIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=UPI0004F8C26A ----AQAELAALEKASNGRLGVAALDSSSGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP -QAVTSFAHESGDTTFRLDRWEPELNRAAPGDERDTSTPLAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAAVPPGWRIADKAGSGGHGTTTDVAVLWPPSRAPIVLAVSFTQ -PAADAAARADVVASAARIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / NRRL B-24157 / PYR-1) TaxID=350058 RepID=A1T7L6_MYCVP ----LDQRIEALGQRHNAQIGLYALDLDTQRGI-EFGADEPFAMCSTFKAYAAAAVLQRTQ -TGELTLNDAIPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSDNAAANGLLRVLGGP -QAITAFARSIGDHRTRLDRWEVELNSALPGDPRDTSTPRALGDGYRNILTGDVLNPPTRR -QLLDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRS -AIPDAPSLRPLIGELAALAL--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. YC-RL4 TaxID=1682113 RepID=A0A172UNT5_9MYCO ----VTLDLAAVEDRYRARIGMFAVDLNSAARL-QHRPDDRFAMCSTFKTYAAARVLQLTA -HGQLRLDTPVLVQASDIVENSPVTSANVGGSMTVEQICAAALEKSDNTAGNLLLQRIGGP -PAITTFARSVGDDQSRLDRWETELNTALPGDPRDTTTPRALASGYREVLVGDALTHELRE -RLLSWMTANATSQKRFRAGLPAGWTSADKTGAGDFGSTNDAGLLIGPAGQRIVMVVLTRS -RDYDTPPLNEAIADTVRLTVDRf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium insubricum TaxID=444597 RepID=A0A1X0DEG1_9MYCO ---RATAELGALERRFGGKLGLFALDTANGSTV-SHRGDERFLMCSTVKTFIAATVLHRRL -TEAGLLDRTIHYTPADILEWAPVTATHLYDGMTVAQLCEAMITQSDNTAANLLIATLGGP -AVTQEFVRTLGDNISRMDRNETALN--YPDGDKDTSTPAQLVSTLTRVALDDGLDPHGRE -LLTGWLKANTTGGETIRAGVPARWTVGDKTGSGFAGQANDIAVLWPPDRAPIVIAALTAP -DDRASDQGKPTIAEATRIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces ipomoeae TaxID=103232 RepID=A0A540P4M9_9ACTN ------------EKEFDARLGVYALDTGTGRSV-GYQADDRFAYASTFKALAVGAILRKYG ---TDGIDKVVRFSRDDVVADSPVSENFVETGMTLRGLCAATLWYSDNTAVNLLLDELGGP -DGLERVLERLGDDVTEMDRYEPDMSDGIPGDIRDTSTPRAMAGSLRAFLLGDALKRNERR -LLRQWMTTNMTGRNLIRAGVPDDWEVADKSGSAGYGGRNNIAVVWPSDGNPIVMAVLSTR -DKQGAERRDALIAKAATVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cenocepacia TaxID=95486 RepID=A0A071MEL5_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVMAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESRVDTGMTIAQLCEAMLQAGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLHEPQRT -QLTEWMAGGARGATGIAAGVPPGWRVADKAATGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -QRADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=Q9XBX1_SALTM --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KKESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=B8LF86_STEMA ------ADFAALEKASGGRLGVTVLYTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTGPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces vitaminophilus TaxID=76728 RepID=A0A0T6LKS3_9ACTN -----ARRLRVLEREHGVRLGAFGWNTTTGRRV-AHRGDELFPMCSVFKTVAVAAVLRDLD -RDGTFLPRVVRYTSRDVERHAPLTGLNLAAGMSVGRLCGAAVSHSDNAAANLLLEQLGGP -AAVTAFCRSVGDDVTRLDRWEPELNSAEPGRVTDTTSPEAIGRTYARLVVGKALDPGDRE -LLAGWLLGNTTGGGRLRAGLPRGWTVAEKTGTGGYGTTHDVGVAWPPGGGPVVMAMLSAT -RDADAAADEPVIARAATVVA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB3 TaxID=2015565 RepID=A0A257CUU8_9BURK --------LAALEKKVGGRLGVAILNTASGATV-GHRLDERFGMCSTFKLPLAAAILRKAD -QGTLRLDQWVPYTQADMVSHAPVTQANLHKGMTVGALAEAAQTTSDNPAANLLLGLIGGP -AGFTALMREAGDTITRLDRLEPHMNAVGHADPRDTTTPAAMAANTARMLLGDWLSAGSRA -TLIDWMVATGTGAKRLRAGFPAHWRAGDKTGTGMMDKYNDIAIAWPPGKAPLIVTAYYET -AKKMRDEDQAVLAEVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075E99B5 -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTVAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Rahnella TaxID=34037 RepID=D7PII4_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKESE -VKKNLLTQHVGLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PEKDAK----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces otsuchiensis TaxID=2681388 RepID=UPI0010317947 ----ADTAFGELEQEFDARLGVYALDTGSGAEV-AHRADERFAVASTFKALAAGAVLDQYG ---LDGLNTLTAFDLDDLVSHSPVTERFAGDGMPLGDLAAAAVRQSDNTAANLLLEALGGP -SGFTEALRAVGDDVTRIDRWETELNDVPPGEERDTSTPRALSETLSTYLLGDILDAQEKD -RLAEWMTTNTTSATLIPAGVPDSWIVADKSGGASYGIRNDIAVLWPEEGEPVLLSVLSNR -DEEADESDDALIARAATAALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora bangkokensis TaxID=1193682 RepID=UPI001300E148 ---TAQRELAALEEVMGGRLGVYAVDTGSGTEV-RHRADERFLMCSTAKVLVSSAVLQARS -GQPGLLDRVIRYTPADLLAHSPTTAQHVSEGMTVAALCEAALTVSDNPAYNLLLPLVGEP -EGLTAYLRTLGDTTSRCDRTEPTLNDTTPGDTRDTSTPAAYAATLRKLTVENALSAENRT -QLLTWMRASTTGKDLIRAGLPPTWDVADKSGSGSQGEVNNAATIQPPGRAPWVIVLFTAP -TKP-GATTRPTLAEATRTIAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Poseidonocella sp. HB161398 TaxID=2320855 RepID=UPI001107FCEB ----LGATLASLEERLGARAGVVLVDTATGRRW-GYRAQERFAMNSTVKVPVCGAILERAE -HGSLALDDVLPVPEEEILDYAPVTEKAAGGGMAIGDLCLAALDMSDNTAANLLIDRLGGP -QAVSAFLRALGDPVSRLDRREPALNDVPPGELQDTTTPAAMAASLQALFLGDALSPASRA -QLAGWMSHGGVTGALVRAEAPAGWQIADKSGAGAQ-TRNLVALVTPPGRDPWVLAMYLEA -PGRDFATRNAALREIGAAAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. IDO3 TaxID=1705310 RepID=A0A2A4CG27_9BURK ---AAQADLATLEKASNGRLGVAVLDTSNGTRI-AYHARERFPLCGTYAVSAAAAILARGA -LDASLLPRRILYRRYDVVAGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMNVLGGP -QSVTAFAHESGDTTFRLDRWEPELNEAAPHDVRDTSTPVAMVDMMKRLLLGDTLGEPQRA -QLTEWLAGGARGATGIAAGVPSGWRIADKAGSGGYGTTTDVAVVWPPSRAPIVMAISFTQ -PRADAAARADVVASAARIAS--- ->[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q93D81_ATLHE ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRVDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANETIAEIGKQLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. ENV425 TaxID=2042960 RepID=UPI000C9CDACA ---RLDAVLADLEERRRVRLGVLAHDPGRGLTY-ARRADDRFAMCSTFKVYAAAAILRLES -QGSLRLDDTVPVDPADIVENSPVTSEAQGRTLTLAQLCDAALTRSDNTAGNLLLRRLGGP -TAVTAFARSLGDTATTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLMGWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] Beta-lactamase OXY-1 n=2 Tax=Legionella jamestowniensis TaxID=455 RepID=A0A0W0ULU2_9GAMM ---PLQEKLAELEVSAGGKIGVSAVNTANNQHL-QYRAMERFPMGCTSKVVGVAAILKKSM -SDPTLLQHKMHYKKEDLAAWSPITEKHVADGMTVSELCAAAITVSDNTAMNLLVKKLGGL -QAINAYARSIGDKYFRVDNWPKEAFSGGEGNLYDSSTPAAMEKSLTKLTLGDALARSQRE -QLLKWLKDNTTGETRIRAGVPKNWMVGDKTGTGSYGTTNDIAIIWPPGCAPLVVTIYFTK -DKKDAVKQDEVVASATRLLLDEf ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter bohaiensis TaxID=2201898 RepID=UPI000DAEA2B0 ---RLSDTVEKVENQLDARVGLSLVDTGSDFSW-SHRADERFLMNSTIKVLICGAVLARVD -EGAMSLADPLPVRQDDILSYAPVTKEQVGQDMTLGELCYAALDMSDNTAANLLLEHLGGP -ASVTRFLRRIGDSVSRSDRYEPALNTGAPGDPQDTTRPVAMSDTLSKLLLGEALTADSRD -QLVAWMSHGGVTGALLRDDAPASWHIADKSGSGDT-TRNIVALITPDDGAPRIVTLYISD -ADADFKTRNAALKELGAAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A4P8JHB0_ALCFA -----AQAAQVVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQYVPASQLCAITMRNSDNTAANGVLEMLGGP -EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVAAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase n=2 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A0D1GG05_VIBPH ---KLNEDISLIEKQTSGRIGVSVWDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLNKNATARIDERNIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTLFLRSIGDKATRLDRLEPRLNEAKPGDKRDTTTPNAMVNTLHTLMEDNALSYESRT -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGNYGSRGISAMIWKDNYKPVYISIYVTD -TDLSLQARDQLIAHI-------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KIT9_9BACT ------SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQWAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter enzymogenes TaxID=69 RepID=A0A1H2RD47_LYSEN ---ALGERLAKLEQRSGGRLGVAVLDTADGRHW-ATRGDERFAMCSTYKLPLVAAVLRKAE -LGEIDLYARIAVPQAALVPYSPATAPIARAGASVAQLCEASMTISDNTAANLLLPLVGDP -AGVNRFLHGIGDDISRMQRMPGAPLRA--GDANDTTTPNAMLATMRRLLLGDALNPASRQ -RLTEWMLASKTGDTRLRAGLPQRWRVGHKTGTGQ-GTANDIAIVWPGRRKPVLIASYLTD -AWGDDELRNSVLADVARTLAAHw ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. Leaf88 TaxID=1736244 RepID=UPI0006FE08D7 -----GAALARIAGDLGGRAGIAVLDTGGGPAL-LHDAEGAFPLCSTFKLLLAAAILARVE -AGRERLDRRHAYGEADLDTYAPVTTRALRAGMSVEALCAAALVWSDNTAANLLLAALGGP -AALTAYGRDLGDPVTRLDRTEPDLNAAVPGDPRDTTRPAAMAATVGKILLGPSLTEASRA -RLEGWMTASRTGTKRLRAGLPGDWGVGDKTGSGAYGTANVVALLRPPARAPLVAAIYLTG -SDTTSEARDAAHAAIGRVIAATy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. L-1-4w-11 TaxID=2572576 RepID=A0A4U1L365_9SPHN ----ADGALEALRRRADVRLGLAVHDTGTGRRL-TIDGMGRYAMCSTFKAPLAAAVLARVD -AGRLRLDQPVRFGDGDLLDYAPAVRARRAEGMTVAELCEAAVVLSDNSAANLLLPLIGGP -AGLTRWFRSMGDGVSRLDRTEPTFNDVRGDETRDTTSSLAMAATLERMLVGDVLSSASRA -RRIEWMVASRTGASRLRAGLPADWRAGDKTGTSGDGWFNDIAIIWPPQRKPIVVACYLDA -PGADTAVADAVHADIGAQI---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000DC5ECE3 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTENHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] L2 family class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00049FFE88 ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -ARRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWWVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium pulveris TaxID=36813 RepID=UPI00138BAD9E ----IEAQIAALERRHNAVIGVYASNLDSPRTV-AHRAQERFAMCSTFKTYAAARVLQMAD -RGELSLEQSLFVDPKDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP -QAITTFARSIGDAESRLDRWETALNSAIPGDPRDTSTPRALGNGYRNLLAGDALAPPQRS -LLEDWMRANQT--SSMRTGLPDGWTNADKTGSGDYGSTNDVGIAYGPENQRVLFALMTRS -QTSDAQGLRPLIGELTSVV---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces vitaminophilus TaxID=76728 RepID=UPI0003A1EBA4 -----ARRLRVLEREHGVRLGAFGWNTTTGRRV-AHRGDELFPMCSVFKTVAVAAVLRDLD -RDGTFLPRVVRYTSRDVERHAPLTGLNLAAGMSVGRLCGAAVSHSDNAAANLLLEQLGGP -AAVTAFCRSVGDDVTRLDRWEPELNSAEPGRVTDTTSPEAIGRTYARLVVGKALDPGDRE -LLAGWLLGNTTGGGRLRAGLPRGWTVAEKTGTGGYGTTHDVGVAWPPGGGPVVMAMLSAT -RDADAAADEPVIARAATVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D005F2B ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia latens TaxID=488446 RepID=A0A1B4P1I8_9BURK ----AQAELAALEKASNGRLGVAALDTSSGTRI-AHHARERFPLCGAYAVVAAAAILARGS -LDASLLPRRVLYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLVMGVLGGP -QAVTSFAHESGDTTFRLDRWEPELNRAAPGDERDTSTPLAMVDTLQRLLLGDTLREPQRA -QLTEWMTGGARGATGIAAAVPPGWRIADKAGSGGHGTTTDVAVLWPPSRAPIVLAVSFTQ -PAADAAARADVVASAARIVT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A4Y5QBA8_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAEKDLLSYAPVARRHVGKGLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSVTRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGAAWVVTAYLQG -ASVD------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI0007566842 ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLVMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI000752005B ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAAAAMLARGA -LDESLLPRRILYRRYELVPGSPVTERHADTGMTIGQLSEAMLQFGDKSAANLVMSVLGGP -QTVTEFARASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPGRA -QLTKWLLGSANGVAGIRAGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=A0A1U9LHH7_9PROT -------VIAVYEKATGGRIGMYACNLATRQRL-TWRENERFALCSTFKVSLVALVLQRVE -QGKDRLDEAVSYTKADIERYAPVAQASLEAGMSVRALCQAAIEQSDNACTNLLLARVGGP -ENLTRFWRSLGDQTTRLDDWEPDLNRVPPGSVRNTTTPAVMAGVLEHLLFGEVLSASSRL -LLTEWLKGCQTGRNRLRAGFPAGWEVGDKTGTNGQDAAGDCAVAWPSPRTPLIVCVYTRG -GHPAEDQFRAAFAGIARLA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium moriokaense TaxID=39691 RepID=A0A1X0HIQ4_9MYCO ---SVDASIEDLEQRNNAAIGVFAANLASGKTV-AHRAQDPFAMCSTFKAYASARVLQMAQ -HGELSLDDTMFVDPAGILPNSPVTQPRAGGDMTLAELCQAALQQSDNAAANLVLTRIGGP -QAITAFARSIGDESTRLDRWEIELNTAIPGDLRDTSTPEALGGGFRALLTGDVLASPQRR -LLEDWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGERVLLAFMTRS -KADDAENMRPLIGELAALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. UNC363MFTsu5.1 TaxID=1449069 RepID=UPI00048021B8 --qSLDSTLDALEARYSTRIGVTAIDPASGRTY-RHRGEERFALCSTFKTYAAAEVLRRTV -TGASSLEEPVMVDPGDVVENSPATEAAAGTTMTLRQLAEAALTRSDNTAGNYLLEEIGGP -PAVTALARDIGDESTRLDRWEPELNTALRGDPRDTSTPDGLAQGYRALIVGDALGSAERA -QLGDWMRASKTSDKRIRAELRPGWTAATKSGAGSFGTVNDAGVVWDPDGNPLVLAILTDS -LTADAQGNNQAVADTAAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Roseibium sp. TrichSKD4 TaxID=744980 RepID=E2CMP1_9RHOB ------EQFQAFEHELGGRLGVAIWDLETGSKT-GWRADERFAMNSTFKFMLVAATLKRIE -NGDEQFDRSIDIDEADLVPWTPVTEKHIGQTMTIHELCSAVMTKSDNLATNYLLKAMGGP -AKLTALLRDAGDDVSISSRYEPEANAVGQNDDRDTSTPNAMVSNLERFVLGSTLSKASRA -QLFDWMVENTTGLKRIRGGLPDDWNAGDRTGTGSGGRASNIAIAYPPGRAPVLFAVYTDG -SHRYPRDISKVHAEIGRLVSE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A212NCV8_KLEPN ------------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A1D7ZKC3_9BURK ---TAQAELAALEKASNGRLGVAALDTSSGVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHDSGDPTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDTLREPQRT -QLTEWLTGGARSAAGIAAGVPSGWRIAGKAGAGGYGTTTDIAVVWPPSRAPIVMAVSFTQ -PQADAAARADVVASAARIVTGAf ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas sp. 43NM1 TaxID=1904755 RepID=A0A2N1DX43_9PSED ---DIEIQLQKLEREHGGRLGVALMNCSTGAIA-SHRGNERFLFNSTSKLFIAAAVLARVD -SGEETFDHRLVVSESDLGGWTPITEKQLGEPITVAELCQAAVAWSDNAAANVLIRSVGGP -EAVTAYLRSISDDTTRLDRYEPDLNEDHEGDERDTTTPLAMMKTLQLLLLGEVLLPSSRH -QLAAWMIEGKTGGARLRAGMPASWLVGEKTGTNGVGNANDIGVAWPADRGAVIAIAYTFM -PNASKEQRDKAIALIGKLA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU17325 TaxID=2015348 RepID=A0A228IBF1_9BURK ---AAQAELTALEKASNGRLGVAALDTSSGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLHEPQRT -QLTEWMAGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinokineospora spheciospongiae TaxID=909613 RepID=W7J1S7_9PSEU -----AEELVALESTFGGRLGVYAVDTADGTEV-RHRADERFLMCSTAKVPVSAAVLRRRL -AEPGLLERVIHYTEADLLEYAPVTSEHVAEGMAVADLCVAALTRSDNTAVNLLLPLVGGP -AGVTDFVGTLGDRTTRFDRPEPDLNVTAPGDERDTSTPLALSSTVRALVVGDGLDRPGRE -LLAGWMRASVTGKDLIRAGVPAGWDVADKSGSGAQGEVNNVAVVWPPNRAPWVITVFTSP -TDPKTTRGRTTVAAAAGIIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000751E84C ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00746D ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0012AD538D ---ALVDIIKQQEKALNGSIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHDPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007530A87 -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Class A beta-lactamase n=2 Tax=Streptosporangiales TaxID=85012 RepID=A0A1U9ZR50_9ACTN ---QVTKELRALEASFKGRIGAYAIDTATGKTV-GYRSGERFPLLSTFKAPLCAAALHRAR -TEPGLMEKVVKWTADDLKPNSPTTEKHVEDGLSVAKLCEATITESDNTAANMVLKQIGGP -AGLTKYFRSLKDPVSRLDRYETELNDWTPKEKRDTTTPAAIARDLRALTTGGALNAKDRE -QLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNGIGGANDIAVAWPNGTAPIILAVYTHR -TV--AATDDSVVAKTATILA--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. 37zxx TaxID=1550073 RepID=UPI00053BFC2E -----RNPFEAIRAETGGRLGLAVHDSGTGRRL-SLDADSRFAMCSTFKAPLAAAILARAD -AGRLDLAQMIRFGEGDLVGHSPTTSANVAAGLSIEALCEAAVTVSDNGAANLLLPQLGGP -AGLTRFFREQRDTVTRLDRDEPSLNLVRGGDVRDTTTPQAMAALLEHLFTANTLSPASRD -KLLGWMRVSTTGLARLRAGLPKSWQVGDKTGTSGEGYVNDIAIATPPGRKPIFIACYLDA -PGLAPAKAEEAHARIGSLIGDLf ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0012AEA490 --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRAIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium gastri TaxID=1777 RepID=A0A1X1UW73_MYCGS ---NVQGRFAELEHRYAARLGVYVPASGPTAAI-AYRADERFAFCSTFKGLLVAAVLHQYP ---LSHLDKVVTYTSADIRSTSPITQLHVATGMSVGELCDAAIRYSDGTAANLLLADIGGT -TAFTGYLRSLGDSVSRLDQEEPELNRDPPGDERDTTTAHAIALDYQQLVLGDALPADKRA -MLTDWMARNTTGAKRIRAGFPADWKVIDKTGSGDYGRANDVAVVWSPSGIPHVVAILSDR -AGYDAEPSEALVADAARCVAQ-- ->[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A2S5E7H8_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARTSGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA -RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=A0A1G7P8M4_9PSEU -----HDALTELEKKFDARLGVFAA--GGDRTV-EHRADERFAFCSTFKGLAAAAVLHHHP ---MTHLDTVVTYTEADLMKSSAITRQHVRTGMTLRDLCDAAVRHSDGTAGNLLLREAGGP -AELTAYLRGLGDTVTRMDRIEPDITSAVPGDPRDTATPRSLGTDYRRLVLGDALPPEKRA -FLTDLLERSVTGAKRVRAGAPAGSRVAGKTGTGGYGTVNDIAVVWPPGREPVLVAVMSSR -AAADAGYDEALVAEAAAYVLK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A5N7ZRW2_9BURK ---TLSRELVRLETASRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD -RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATITTSDNTAANLMHRSYGGP -QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ -LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET -TAVPMPERDGIIAEVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075FDDBB ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCMAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. 381-Salad TaxID=678983 RepID=D7PIK5_9GAMM ------------------------------SQI-AYRADERFAMCSTSKFMAASAILKESE -VKKNLLTQHVGLKKSDLVNYNPITEKHLKEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGDKTGSGDYGTTNDIAVIWPENKAPLVLVTYFTQ -PEKDAK----------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=A0A3R9G643_ACHDE ---TLSRELVRLETASRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD -RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATITTSDNTAANLMHRSYGGP -QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ -LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET -TAVPMPERDGIIAEVGRLAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides immunogenum TaxID=83262 RepID=A0A0N1LXF3_9MYCO ----KSTELASLEQDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQADLQEWAPIASQHVGEGMTISELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRLEEQLN--IPDGDLDTSTPSQLVTNLRRLVLDEGLDGPGRE -LLTDWLKRNTTGDQSVRAGVPAGWTVADKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP -DDPKSTKGKPTIAAATRIVLKAf ->[subseq from] Beta-lactamase class C n=1 Tax=Burkholderia sp. JKS000303 TaxID=1938747 RepID=A0A2A9M2B8_9BURK ---AAQADLATLEKTSNGRLGVAVLDTSDGTRI-AYHARERFPLCGTYAVSAAAAILARGA -LDASLLPRRILYRRYDVVTGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTTFRLDRWEPELNDAAPHDVRDTSTPVAMVDMMKRLLLGDTLGEPQRA -QLTAWLAGGARGATGIAAGVPPGWRIADKAGSGGYGTTTDVAVVWPPSRAPIVMAISFTQ -PRADAPARADVVASAARIAS--- ->[subseq from] Beta-lactamase n=3 Tax=Vibrio TaxID=662 RepID=A0A0P7F1J4_VIBAL --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007541AB3 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNRAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI00063DADAF --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=UPI000B7E5B85 -----HDALTELEKKFDARLGVFAA--GGDRTV-EHRADERFAFCSTFKGLAAAAVLHHHP ---MTHLDTVVTYTEADLMKSSAITRQHVRTGMTLRDLCDAAVRHSDGTAGNLLLREAGGP -AELTAYLRGLGDTVTRMDRIEPDITSAVPGDPRDTATPRSLGTDYRRLVLGDALPPEKRA -FLTDLLERSVTGAKRVRAGAPAGSRVAGKTGTGGYGTVNDIAVVWPPGREPVLVAVMSSR -AAADAGYDEALVAEAAAYVLK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A4R5P9F8_9MYCO ----KSTELASLEKDFGGRLGVHALDTGSGDTL-SHRTNERFIMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQADIMEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRLEEDLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD -LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075F459C -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] UPI001444F354 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001444F354 ----LSRELRALEGRFGARLGVFARNAVTGASV-RYRAGETFPICSAFKTLATAAVLRDLD -QNGEFLAKTIRYTAQEVEDYGPITGENLAHGMSVEALCAAAVSYSDNAAANLLLRELGGP -RAVTRFCRSLGDPVTRLDRWEPELNSAEPWRTTDLTTPAEVGLDYGRLVLGKALPRGDRE -LLTGWLRGNTTGDARLRAGLPEDWTVADKTGTGEYGTTNDVGIAWTGDGTPLILSVLATQ -PDPEAPAVDALIAETARLLV--- ->[subseq from] class A beta-lactamase n=2 Tax=unclassified Rhodopseudomonas TaxID=2638247 RepID=UPI0013E0080A ---EIEGRLRDLERSSGGRLGVAILDSKDGRLV-GHRLDERFALCSTFKALAVAFVLARVD -RGEESLDRRIAFTERDLVSPFTATKPHVGAEMTVAALCEAAITVSDSTAANLLLDSFGGP -SALTAYLRSLGDPVTRVDHRELELNIVRPGEIHDTTSPRAMVGTLQRLLLGSALSASSRA -RLTTWMIEARDAARRLRVGLPNGWRIANKPGTWAKISTNDIGVIWPPGRDPIIVAAYLGE -APGSIKDQEAVLAQVARIIAE-- ->[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=A0A200HHB7_9ACTN --------LSAEAAEAGVDLSATVTDLGSGETF-QIGGQEPVKAASIIKLPLLAALMDEAD -RGRLSLDEVVTIEASNIVGGSGTLRDREPLDISIAELMELMVQVSDNTATNVLIDRAGGF -DGVNEYIEGLGFEHLWLGRKMI--HPASPPLQENWITSGEVNELVRMLYEHEVLSPESSE -HIISLMKGQLV-DTKFGAVIPRE-VLANKTGELAD-VSHDSGLILVPGRE-VALTVTTSF -DPIQRPQVDVYVQRAASIVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=A0A200HHB7_9ACTN -----------EARTKGIEIGVAIEDLSEDRQL-FLGAQDRFTTASTIKMSLAAAVMHQVE -RGQLSLDDVVTITEDERYGGSGTLKDNPFPQVSVGRMLDLMVTVSDNTATNKLVDVVGGF -EAINTLTQGSGIPQRDLHFGRKMFGPVVPPDGDVWLTPRGMNQLMVLFYDPEFLSAESAQ -HIVELMLAQQV-KTKLGATVPAE-VLAHKTGENDV-VSHDVGMLLVPGQ-EMTLSVFSRG -VEDVQATANPYLQRIGAAVYAY- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces aquilus TaxID=2548456 RepID=A0A3Q9BVG3_9ACTN ----APEGLRELEARHGARLGVFARNIVTGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDRA -LLTHWLRNNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL -PAQDAARDDVLIRDTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. SLBN-53 TaxID=1570328 RepID=UPI0011523625 ---ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAGESFAMCSTFKAYAAAAVLRRVA -DGELSLEKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP -RAITDFARSIGDDTTRLDRWETDLNSAIPGDPRDTSTPEALGMGYRNLLAGDALPPVQRD -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGTRVLLSIMTRT -QSPDAEGLRPVIGEVAALVL--- ->[subseq from] serine hydrolase n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=UPI000B3ECDB1 --------LSAEAAEAGVDLSATVTDLGSGETF-QIGGQEPVKAASIIKLPLLAALMDEAD -RGRLSLDEVVTIEASNIVGGSGTLRDREPLDISIAELMELMVQVSDNTATNVLIDRAGGF -DGVNEYIEGLGFEHLWLGRKMI--HPASPPLQENWITSGEVNELVRMLYEHEVLSPESSE -HIISLMKGQLV-DTKFGAVIPRE-VLANKTGELAD-VSHDSGLILVPGRE-VALTVTTSF -DPIQRPQVDVYVQRAASIVYD-- ->[subseq from] serine hydrolase n=1 Tax=Aeromicrobium sp. PE09-221 TaxID=1898043 RepID=UPI000B3ECDB1 -----------EARTKGIEIGVAIEDLSEDRQL-FLGAQDRFTTASTIKMSLAAAVMHQVE -RGQLSLDDVVTITEDERYGGSGTLKDNPFPQVSVGRMLDLMVTVSDNTATNKLVDVVGGF -EAINTLTQGSGIPQRDLHFGRKMFGPVVPPDGDVWLTPRGMNQLMVLFYDPEFLSAESAQ -HIVELMLAQQV-KTKLGATVPAE-VLAHKTGENDV-VSHDVGMLLVPGQ-EMTLSVFSRG -VEDVQATANPYLQRIGAAVYAY- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sienata TaxID=248552 RepID=UPI000A0020AD ---DLSNTLMTLQAKYNVLFGIAAVDTRGRRTF-EWNADDRFAMCSTFKVYAVAAILRLAE -REELDLNDRVPITREDIVMNSPVTFDHIGELMSYYELSRAALVRSDNTAANLLLRRLGGP -RAVTEFARSINDSQTRLDRWEPELNEARAGDPRDTSTASAFAAGYRKLILGDGLSTEYRR -MLTSWMRSSVTSRARLRAGLPLGWVAADKTGSGAYGTANDAGVVWSPNGTSLVLVIFSRS -TTPMAAGADAAVADAAAAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Achromobacter veterisilvae TaxID=2069367 RepID=A0A446CQY1_9BURK ---SLNQALAKLEAASKGRLGVSLLDTASGQAA-DYRGDERFLMLSSFKTLAAAYILARAD -RGEDQLDRRIPIAEADLLEYAPVTRLHVGPQMTLAGLCEATITTSDNTAANLMHRSYGGP -RALTRFIRGLGDTVTRHDRYEPELNRPHAGEPLDTTSPHAMSRTLGILLFGPALQPGSRR -LLQSWLLASTTGGKRLRAGFPADWKVGEKTGTDSQVGANDAGFAQPPGGAPIVVSAYLET -TAIPMAERDRIIAEVGRQAA--- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2S2CJ31_9GAMM ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLVCAKLLADSD -KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D07F0E2 ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLVCAKLLADSD -KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Arthrobacter sp. SLBN-53 TaxID=1570328 RepID=A0A542P1E6_9MYCO ---ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RHRAGESFAMCSTFKAYAAAAVLRRVA -DGELSLEKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP -RAITDFARSIGDDTTRLDRWETDLNSAIPGDPRDTSTPEALGMGYRNLLAGDALPPVQRD -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGTRVLLSIMTRT -QSPDAEGLRPVIGEVAALVL--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q9JRP6_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSMLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFAKGDPRDTTSPAAMATSLARFAVGNGLQPASRR -QFADWLIDNQTGDACLRAGLGKRWRVGDKTGSNGDDTRNDIAVLWPHGGTAWVVTAYLQG -ASVDDDQRAAVL-QVGR------ ->[subseq from] class A beta-lactamase n=1 Tax=Oceanicola sp. HL-35 TaxID=1305735 RepID=UPI0004631453 ----LFQTIESIEDRLDARVGLYIRDSGSDWSI-SHRADERFLMTSTFKPMLCAAALRQVD -EGTLNLDAALRIEQGAILDYAPVTQTMVGRTMTIDDLCFAALDMSDNTATNLLIDHIGGP -EAVTRFLRDIGDPVSRLDRREPELNTFAPGDPRDTTTPEAMAATLETMLMGDALTAQSRA -RLIDWMSHGGVTGPLIRASTPADWLIADRSGSGNF-NRNVIAMVTPPDQSPYFISVFLSD -ADADFETRNDAVIGLSQAVMD-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2T3QJQ4_9GAMM ---ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q2XQU6_PSEAI --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFTTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio chagasii TaxID=170679 RepID=A0A2S7VP23_9VIBR ------ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE -HKGLDLDSKVSIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIEGP -NGLTQFLRSIGDSHTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASTS -TLTGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWNEHRAPLIISVSLTE -TEFTLQQRDKVINEVGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI00021C2EE7 ------ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE -HKGLDLDSKVSIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIEGP -NGLTQFLRSIGDSHTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASTS -TLTGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWNEHRAPLIISVSLTE -TEFTLQQRDKVINEVGQLIFDAy ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium sp. Root265 TaxID=1736504 RepID=A0A0Q8ZWG2_9MYCO ----ADSDFAALEHRHGARIGMWALDLGTGQTL-GYRPDDRQAMCSTFKTYAVGRVLHMVA -GGVLDLNSAIPITAGDIVVDSPVTSKRVGTSMSLAELCEAALVFSDNSAGNALLRSIGGP -PAITSFARGLGDDQTRLDRWEPDLNSALPGDPRDCTTPRALVTGYRALMVGDALDPPSRD -RLLSWMQANVTSDKRFRAGLPPGWTSADKTGAGDFGVTNDAGLLIGPTGQRILVAVLTRS -AEMDAPRLNDAVADTVRLTLAR- ->[subseq from] class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI000F504684 ---TLSRELVRLETASRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD -RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATVTTSDNTAANLMHRSYGGP -QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ -LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET -TAVPMPERDGIIAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Pararhizobium sp. BGMRC6574 TaxID=2590452 RepID=A0A506U760_9RHIZ --dALSDAVAQVERQLGARVGVTLSDTGSDLAW-SNRSDERFLMNSTVKVAICGAVLARRD -AGKLPLSDTLPVRKADLLSYAPVTKTHVGGRMTIANLCLAALDLSDNTAANILTDRLGGP -QAVTRFFRSIGDGVSRSDRHEPELNTFEPGDPRDTTTPSAMAQTLRKLLLGNALSPASRD -QLAEWMSHGGVTGDLLRADAPKDWRIYDKSGSGDH-NRNIFAVVVPKGRAPWIVTIFISD -TDAGFETRNDALKTIGTAAME-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. LHW50302 TaxID=2250578 RepID=A0A367F4D4_9ACTN ---AAAAAFKKLEAQYGARLGVHAFDTGSGRAV-SYHADERFAYASTHKVFTAAAVLDKYS --LKGLGDKSLTVGKDVPVGHSPVTSAHVGQQLTLRELCEAAVRQSDNGADNLLVRDLGGP -EKLDAYLEDLGDDVTQMNRYETALTEATPGDKRDTTTPRAFAEDLRAVTLGDALPKPERA -QLDDWLDESPTGTELIRAGVPKEWGVGDKSGAARYGTRNDIAVVRPPGKAPLIVTVMSKR -KKEDADYDDKLVAEAASVVSD-- ->[subseq from] Beta-lactamase n=1 Tax=Thalassotalea sp. PP2-459 TaxID=1742724 RepID=A0A1Q6CH20_9GAMM ------NQIKKQERLLNADFGVAIFDVEKQSLW-HYNGNSRFPLMSTFKVLACAKLLADVE -KGVQSFDSSTLITKSDLVYWSPVTKHMVGKKMSLKQACSATMTMSDNTAANIILTGIKGP -TALTKFMRDIGDNVTRLDRIEPELNQALKNDKRDTTSPIAMVKSLHTLLFGNILKDPSKA -QLTQWMIDNKVTASLLRSVLPEHWSIADRSGAGGYGSRAIAAVVWSKDQTPLIISIYLTQ -TEATMKERNKAIAAIGESIFTFy ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium chubuense (strain NBB4) TaxID=710421 RepID=I4BHU3_MYCCN ------ERVEALQRRYNAEIGLYALDLGSGKAL-AFGADEPFAMCSTFKGYASAAVLQRAQ -RGQLALTDTVPITRGDIKPHSPLTEPRVGTAMTLAELCQAALQQSDNAAGNLLLRTLGGP -PAITAFARSIGDDRTRLDRWETELNSAEPGDPRDTSTPHALGEGYRALLAGEVLDAPGRG -QLEEWMRGNQT--SSMRAGLPQGWTTADKTGSGGYGTTNDVGVAYGPGGTRLLLSMLTKS -AGPDAQGLRPMIGELAALVL--- ->[subseq from] LAP family class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011108292 ----VTDTIQSTEDHIKGRVGFTEIDFLSGKVLsSHRREERFPMMSTFKVLLCGAILVRVD -KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP -EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK -KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN -TQ--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Pseudohoeflea suaedae TaxID=877384 RepID=A0A4R5PJF3_9RHIZ --sDLERTVAKVEQQLGARVGLSVVNTDSGITW-FHRKNERFLMNSTFKVPLCGAVLARVD -KGELSLTDTLPVAQSDLVPHAPITERRVGGTMSLAELCRAAIDMSDNTAANLLIDYLGRP -DEVTRFFESIGDSVSRLDAREPELNAFVPGDPENTTSPAAATQTLHALLIGDALSPESRD -VLRGWMSDGGVTGDLLRDYVPAGWQVFDKSGAGSH-TRNLVALVVPQDGTSWIVTIFVSD -VDAPFKTRNDALRQIGKAVVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Ruegeria sp. EL01 TaxID=2107578 RepID=UPI0013C40FDD ---DATARLESAEQRLSARIGVHAENLSTGQVF-QHRPDERFAMCSTFKASLAALCLHRSD -RGQLDLDERLAFQGSDILPTSSVTRGNLSAGMSISDLCQAIVEYSDNTAANLLLKHIGGP -SAITQFFRDIGDTTSRLDRTEMALNSNIAGDERDTTSPQAMARTLSELTMTNLLSDHSRA -LLIQWMRNEQNGQNRIRAAVPGDWAVGNKPGTSPNGVANDIAVLWSPDGTPFVVTVFIDT -QQGRAREAVAAIHDIAGTAL--- ->[subseq from] Beta-lactamase n=2 Tax=Photobacterium damselae TaxID=38293 RepID=A0A2X1XP38_9GAMM ---ALVNIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0012DF73D1 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKGGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Afipia sp. Root123D2 TaxID=1736436 RepID=A0A0Q6Z2B9_9BRAD -------ALQTYERESGGRIGFHAENLASGAKL-GWRADERFVMCSTFKASLAAFVLARVD -HGEDRLDHMISYGPKDIQPYAPVAKQNLAKGMSMEDMCQAVVELSDNTCANLLLAHVGGP -AKLTEFWRSLGDTVSRLEHYEPELNRTPPGGLDDTTTPVAMAGSLHRLVSGSALSAGSRE -RLTGWMVNCKTGADRLRAGLPKDWKIGDKTGNNGKDGFGDIAVAWPKPDAPIVICAYTRG -GSPTAAQVKTVFTAIGRMAAE-- ->[subseq from] Beta-lactamase n=2 Tax=Corynebacteriales TaxID=85007 RepID=V5XBK5_MYCNE ---ALPERIRDLEARHNAFIGVFGMNLDSGMSV-RYRDGESFAMCSTFKAYAAAAVLRRVA -DGELSLEKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP -RAITDFARSIGDDTTRLDRWETDLNSAIPGDPRDTSTPEALGTGYRNLLAGDALPPVQRD -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGIAYGPGGTRVLLSIMTRT -QSPDAEGLRPVIGEVAALVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia transvalensis TaxID=37333 RepID=UPI000A3070AD ---TAEDYFASLERKYDARLGVYAVATATAVAL-THRADDRFAFCSTFKTLAAAAVLHQRP ---LSYLDTVVRYTREDVNSISPITQDHIDTGMSMRDLCDAAIRYSDGTAGNLLMRDIGGP -PQLTAYLRGLGDTVGRMDQYEPELNSDPPGDPRDTTSPRALAAVYQQILLRGALPPDRQA -LLEDWLRRSTTGANTIRAGVPADWTVASKTGHGDYGRANDVAVVRPAGGAPLVIAVMTDR -AAFDAEPPYAMIADVARYVAT-- ->[subseq from] Class A beta-lactamase n=2 Tax=Mycobacteroides franklinii TaxID=948102 RepID=A0A1S1L6B7_9MYCO -----SPHFAALEQEFAGRLGVYALDTGSGTAL-GNRQSERFLMCSTVKVFIVSAILTRRR -TEPGLLEKRIHYTNADILDWAPVTPAHIADGMTVEELCAAAVSHSDNTAANLLIAELGGP -EETEKFVRSIGDSTTNTDRTETDLD--IPDGDKDTSTPEQLVSNLRTLVLGDALDREGRD -KLIGWMKANTTGEQSIRAGVPHGWEVGDKTGSGSRGESNDIAVIWPPNRAPILLAVLTAP -DDPTSTKGKLTIAQATRQAI--- ->[subseq from] Uncharacterized protein n=1 Tax=Actinokineospora bangkokensis TaxID=1193682 RepID=A0A1Q9LQ82_9PSEU ---TAQRELAALEEVMGGRLGVYAVDTGSGTEV-RHRADERFLMCSTAKVLVSSAVLQARS -GQPGLLDRVIRYTPADLLAHSPTTAQHVSEGMTVAALCEAALTVSDNPAYNLLLPLVGEP -EGLTAYLRTLGDTTSRCDRTEPTLNDTTPGDTRDTSTPAAYAATLRKLTVENALSAENRT -QLLTWMRASTTGKDLIRAGLPPTWDVADKSGSGSQGEVNNAATIQPPGRAPWVIVLFTAP -TKP-GATTRPTLAEATRTIAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00057D3B90 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -HAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI00102DC618 --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQSTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0006261492 ---TVQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDRWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMIGGARGATGIAAGVPLGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A103HS23_BURVI -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A250L293_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLMEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVAA-- ->[subseq from] serine hydrolase n=1 Tax=Georgenia sp. 311 TaxID=2585134 RepID=UPI001111D5D2 -------------AAAGVTLSVAVTGLADGASL-VAGTDERVKAASIIKLPLLATLMADVD -AGHLDLAQVVTIPAGDIVGGSGTLQDRSFPLITVGELMELMVQVSDNTATNVLIDLAGGF -DAVNEYTADLGLEDLRLGRKMI--HPASPPLQENYISAAEVTDLVTLLWDGGILSESSSE -YVLDLMRGQLV-DTKFGAVVP-RAHLANKTGELSD-VSHDSGVILLPGRE-LALTATSSF -TGMPREEADVFVQEAARVVYD-- ->[subseq from] serine hydrolase n=1 Tax=Georgenia sp. 311 TaxID=2585134 RepID=UPI001111D5D2 ----------------GIRASVGFTDLADGGAL-LLGSPAPYNPASVIKLSLLATVMRQAE -RGMLNLDAPVTISPYMVVAGSGSLQHEQMPYTTVRELTRLMVVQSDNTATNVLLYYT-GI -PTTRELLDDLGLEVMRFNRQMFPGDR--ISDPANVLDLADTMGLLEAMYGDDLLAAGSRD -QILTWMGDQEV-DTKFGAVLD-DAPVAHKTGETGN-VTHDVGYFLVPGHE-AAVAVLTEV -TTEAQEIGNPVVQEIGLAIYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI000A1125F1 ---ALSTQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKHDLRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_185 TaxID=2485151 RepID=A0A3N4ZNQ7_9ACTN ----------------------FAHNVRTKQTV-EHRADELFPVCSLFKTLAAAAVLRDLD -RHGEVLARRIHYTEADLVDGSDRTREHLAEGMTVAELADVAIRYSDNTAGNLLLRELGGP -TAITRFARSIGDPVTRLDRWETDLNSAEPWRITDTTTPRAIGRSYARLVLGHVLDRRDRA -LLTHWLLGNTTSGNRFRAGLPKTWTVADKTGGGSYGANNNVGIAWTPDGTPIVLAVQVTK -PDQDAELDNPLIAGTAAFLAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075BEC68 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI0005C1D23A -----HDRLIELERTFDARLGVYALATGTGATI-AHRADERFAFCSTFKTLAAAAVLHRNP ---LTHLDTVVGYTENDLLKNASITPQHVATGMTIRQLCDAAVRYSDGTAGNLLLREIGGP -AQLTEYARGLGDMVTRMDRIEPAITEATPGDPRDTTSPRAFGTVHQRIVLGDALPADKRA -FLRDLLERNATGAQRIRAGVPRGWTVADKTGTGDYGTLNDIAVVWPPDAAPVVVAIMSSK -ATADAP----------------- ->[subseq from] Beta-lactamase n=1 Tax=Pelomonas puraquae TaxID=431059 RepID=A0A254N762_9BURK -------ALRALERRAGGRLGVAILDTGTGAQT-GLRLDERFALCSVFKLPLAAMILRESD -LGRLPLDQAVPFGKADMLNHAPVTSQHLARGMTVAELAEAAQVTSDNPAANLLLKLIDGP -AGLTTRLREIGDATTRLDRYEPEMNQMPPGDARDTSTPAALAALVQRITLGDVLKPASRA -LLVSWMEKTETGRHRLRAGLPKGWRAGDKTGTFWDEKVNDVAVCWPPGRAPLVVAAFYEA -PKADFEAGQKVLAEVGRIAA--- ->[subseq from] Beta-lactamase enzyme family n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A5P8VF64_BURCE ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Nitratireductor sp. TaxID=1872084 RepID=A0A2E0JD53_9RHIZ ---TLSQTVERIESTLGARVGIVIRDTGSDWRW-SHRAEERFLMNSTVKALICGGVLAKAD -AGALALRDALPIRQFDIVSYSPVTQKQVGKAMSIADLCLATLDMSDNAAANLLIGRLGGP -KAVTAFLRDIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMIETWHALLLGDVLKPASRT -QLIEWMSHGGVTGALMRASLPKDWAISDKSGAGSH-TRNLVAMVTPPGRAPFLVSIFISD -TDVDFETRNGALKDISAAIVN-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. JS623 TaxID=212767 RepID=L0IW73_9MYCO ---RIQNRIAALERRYDAYVGLFAVDVDDGRAI-SHRGQEAFAMCSTFKGYASARVLQMVE -QGQLTLDQRVFVDPAATVANSPRTAPRAGGDMTLDELCQAALRVSDNTAGNLLLQTIGGP -PAITAFARSIGDPSTRLDRWETELNSAIAGDPRDTSTPEALGGGYRNLLTGDALAPPQRQ -QLEDWMRANET--SSMRSGLPPQWTTADKTGSGAYGSTNDVGIAYGPDGQRVLLALMTRS -QVNDAQNQRALIGELTALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Microlunatus speluncae TaxID=2594267 RepID=UPI0012664828 ----ADAGLAALEKKFDARLGVFAWDTGTGRAI-THRADDRFAFCSTFKGLAAAAVVQGNP ---LSHLETLVRYGEDELMKSSMITKKHVKTGMTIRQLCDAAVRFSDGTAGNLLLRDLGGP -RKLTEFARSLGDEVTRMDRIEPDIVSAEPGDLRDTSSPRALGGDYHQIVLGEALVPDKRA -VLRDLLERNTTGAARIKAVLPKGWKIANKTGTGDYGTINDIAILWPPKSAPLVISIMSSR -PDRNAAYNEDLVAEAAGHVL--- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3G2HVU1_9BURK ------RAVQEVEHSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLIKEEAIQSYAPTTKKLIGQQVSAAQLCAITMRNSDNSAANGVLEILGGP -EAITSFLRGVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVQTLRNLVLGDALKAPDRD -RLIDWLTHNNVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIATIGKAMA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis alkaliphila TaxID=225762 RepID=UPI000A304C77 ---DLSVEFEALEEEFDARLGVYAVDTGSGEVV-AFREDERFALASTFKALLAGVVLSENS ---LEEMERVVTFDEEVLVPHSPVTEQHLGVGMSLLELCDATVRFSDNAAANLLLDEVGGP -EGFTEALGGTGDEVTNLVRYEVEMAEGVPGDERDTSTAEALVGSLEEFTLGDVLPEDRRE -VLVDLLERNTTGDALIRAGVPEGWVVGDKTGAGGFGTRNDIGVLWPPEGGPIVLAVLSSR -DESGAEHDDALIAQATEVVVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID10853 TaxID=2706028 RepID=A0A6B2SH77_9ACTN ------GRLRALEQEYSARIGVFARDTATGATV-QYRARERFPMCSVFKVLAAGAVLRDLD -RHGEYLARRVHYTEELVEKYTPVTGKNIAGGLTVGQLCAAAVSESDNAAGNLLLSRLGGP -TAITRFCRSTGDSTTRLDRWEPELNSAEPWRTTDTTSPGAVGTTVARLVIGRVLTPYHRE -KLTGWLTANTTDGERFGAGLPADWTLADKTGGGDYGVANDVGVVWPPERPPLVLSVLSTK -YDPQGPTDNPLVARAAALVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000A34379C ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KYKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIVETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTAHEPIVVSIYIQQ -SSASMDERNKAIATIGRQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=UPI0008F4DF6C ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Hoeflea olei TaxID=1480615 RepID=A0A1C1YW23_9RHIZ --aQLEKAVAQVESQLGARVGLAMVDTGTGVTW-FHRKDERFLMNSTFKAPLCGAVLARVD -AGDISLSDVLRIEKADLMHHAPVTEKNVGKDMTIEALCRAAVDMSDNPAANILLHHIGGP -SAMTGYFRSIGDSVSRMDDPEPQLNTFIPGNPRNTTSPAAMAQTLHALLLGDVLSPASRD -LLADWMSHGGVTGNLMRAAAPRSWQILDKSGAGSH-SRNLIAMVTPEGRAPWIVTIFISD -VKAPFETRNAALQSLGRVAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacteroides franklinii TaxID=948102 RepID=UPI0013E89C20 ----KSTELASLENDFGGRLGVHALDTDSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQADIMEWAPIASQHVGEGMTIAELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRLEENLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRD -LLTDWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075265A5 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPSWRIADKAGTGGYGTTADVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Amycolatopsis taiwanensis TaxID=342230 RepID=UPI000693BAA8 ------AAFEELERTFDARLGVYAVDTATGRNL-AYHADDRFGYASTHKVFTAGAVLQRTP ---IEGLERTVTYGANDLVPNSPITQRNLGTAITLRAAMDAALRYSDNTADNLLFREIGGP -AGMAAALREAGDTTTHADRIEPALNDLAPGEIRDTSTPRALAASLRAFTLGEALPEEKRT -ILTDMMRANVTGDSVIRAGTPAGWQVADKTGTAKYGTRNDIAVVWPPQRAPIVLVILSDR -KAKDSDHDDKLIAQAAAAALGV- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Pseudoalteromonas sp. RA15 TaxID=2518973 RepID=UPI0012318026 --qQVEQEARLIEVTLSGRIGVTVLDTKNGEYW-DYKGDERFPLTSTFKTIACAKLLYDSE -QGDINLNSTVKIKKTDLVTYSPVIEKYVGQAITLDDVCSATMKTSDNTAANIIINAVGGT -ESITDFVRHTGDEKTRLDRFEPELNEGIPGDLRDTTTPKSIANILNELLFGSTLSPMSQE -KLKAWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEHQSPIIISIYIAQ -TEVSMKERNEVIAKLGNSIFKVy ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea jiangxiensis TaxID=633440 RepID=A0A1G8CJF4_9ACTN ---RARKELRALEASFKGRIGAYAIDTGTGRTI-AYRSGERFPLLSTFKAMACAAVLHKAR -TSEGLMRKVVRWTAAEVQEYSPVTEKHVKDGLTVAQLCKAAITLSDNTAGNMILKQIGGP -AGLTRYFRTLKDPISRLDRWETELNVWTPKEKRDTTTPASIARDLRAVATGDALTAADRR -QLNAWMRATETGDTRIRAGLPKTWTIGDKTGSNSFGGANDIAVVWPKKTAPIIMAVYTNR -AQG-VAGDDSAVARTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2Q4B0_9PSEU ------EHLVALERKYDARLGVFALNTSTGASL-AHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTLVRYAKQDLLKSGVVTSQHVATGMTIRDLCDAAVRHSDGTAGNLLLRDLGGP -QQLTEYLRGLGDTVTRMDRTEPAIVEATPGDPRDTSTPRSLGTSYQKIVLGDALTEDKRA -FLRDLMERPATGAQRVRAGLPKDWRVADKTGTGDYGTLNDIALVWPPGKAPLLIAIMSSK -AAKDAKYDHQMLAEAASYA---- ->[subseq from] Class A beta-lactamase n=2 Tax=Burkholderia cepacia complex TaxID=87882 RepID=A0A102PIE6_BURCE ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0007573686 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A2X1GKW8_BURCE ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075886CF ---AAQADLTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces olivochromogenes TaxID=1963 RepID=A0A250VRV6_STROL ----------------------------------RHRAAERFPGCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPTTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGDYGTSNDVGIAWTPDGAPVALAVLSTK -PAQDAAADSPLVAATATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kitasatospora sp. NRRL B-11411 TaxID=1463822 RepID=UPI0004C38300 ---RLADSFRQLEREHGARLGVLAHDTGSGATV-RHRADEAFPLCSTFKPLAVAALMRAGD -----DLAARVHYTDADVADHAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP -TAVTRFCRSLGDPVTRLDRWEPALNSAEPDRTTDTTTPRALARTFARLTLGDALARPDRA -RLTAWLRASTTGTHRLRAGLPPSWTLADKTGTGSYGTANDLALAWPPHRPPLVLAVLSTR -PTPTAAPDEPLLARTAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Terribacillus halophilus TaxID=361279 RepID=UPI000984FEDF ------DAFSQLEETYDARLGIFAIDTGSGETI-AYREDERFGFASTHKALSVGVLLLQNS ---VENLNKKISITSDDLVNYNPITEKNVNTQMTLKELSEASISYSDNAAANLIFAEIGGP -KGFEQGLRAVGDQVTDSSRIEPELNHVKPNQIQDTSTPKAMTESLRAFTLEDHLSSEKRQ -LLIKWLKGNTTGDTLIRAGVPADWEVGDKSGAGSNGIRNDIAILWPPDKEPIVLSIMSSR -DKAGEEYDDSLISKATEEVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE50CC ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. I6 TaxID=2483113 RepID=A0A3N0DBG1_9ACTN -----VREFTELEDRFEARLGVYAVDTGTGREV-VHNDEESFAYASTFKALAAGAVLREYS ---LSGLDRVIRYSADEMVAHSPVTAKHVGTGMSLAELCDAAVRLGDNTAANLLLDQMGGP -RGLDAALEEIGDDVTRMERRETQLNEWSPGSLSDTSTPRALAGALRAYALEDALGKGERA -QLTAWLRASATGAELIKAGVPKDWLVGHRAGAGGYGVRNDIAVVWPPDSAPIVMAIMSNG -LRRDADYDDRLIAGAASVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Prauserella rugosa TaxID=43354 RepID=UPI0011A64EAA ---DVAGELAAVEQRFGGRLGVYAVDTGSGALV-QHRQRERFLMASTAKLPIVAATLGRGV -----PLDRSVPVRQEDVLEYAPVTQERAGGVMTVAELCEAAMTRSDNTAANLLTAQVGGP -AEVTGFLREKGDRVTRLDRWEPELNVR--DTRLDTTTPAAMADLTRRLLFDGGLDRAARE -QLTGWLRGNTTGDDRIRAGLPPAWQVGDKTGTGAHGEINDVAVAWPPDRAPVVVAVYTSP -RGATEEAGATALVEAARAVAGAf ->[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T90 TaxID=2696566 RepID=UPI001412D4AB ---AAEARLAQLEEEFDARLGLFALDTGSGRSL-THRADERFALASTYKALAAAAVLDRTT ---DAELDAVVTWRGSDLVDHSPVTGEHVEGGLPLRAVAEAAITVSDNTAANLLLDHLGGP -GGLEEDLRALGDSATEVDSREPAVNDHVPGRARDTTTPRAVATSLRAYALGDALEAGDRE -QLVRWLRANTTGDEQVRAGVPAGWVVGDKTGHAGHGNQNDIAVVWPAGGAPWVLAVLTDR -ADVDAESDDALLARATEVVVQE- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio thalassae TaxID=1243014 RepID=A0A240EKE6_9VIBR ---TLDESIASIEQRISGRIGVSVLDSSTQQQW-HYRGNERFPMMSTFKTLACAKMLHDAD -SGDLDKNALAPITSDKLIPWSPVTEKMVGSSITVSTACEATMETSDNTAANIVLHSIGGP -QGLTEFLRLNQDDVTRLDRIEPELNQVLSGDQRDTTTPNAMNTTLHRLLFEGAMNPGSKN -QLIAWMQGNTVSDSLLRSILPQGWSIADRSGAGANGSRGFTGAIWADNRKPLVISIYLTQ -TDLSMSERNQIINEIGGLIFQTy ->[subseq from] Beta-lactamase n=2 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=A0A1G9A9L1_9ACTN -------SIAALEQKHQRHLGVWARNMRTGRVI-EHRADERFPMLSTFKTLLAASILRDHP ---ARTLQQRLTWDAADVVVNSPITSLTVRNGLTVAQLAEAAITRSDNTAANELLHLIGGP -TGITRFARSLGDSVTRLDRWEPELNSAIPGDQRDTTSPRAIAQTYTKLVLGDALDRADRD -QLITWMLANQSTVTRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTTDGAPIVIAALTRS -DDPAAPPLDVPLADIAATVC--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio chagasii TaxID=170679 RepID=UPI000FE3815B ------ESIEQIESRVSARIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE -NKGLDLDSKVSIKSEDLIVWSPVTKELVDKGISLRDACKATMTMSDNTAANIVLGGIDGP -NGLTQFLRSIGDSNTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASKA -TLKGWMMDNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVALTE -TEFTLQQRDKVINEVGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=A0A1I2EQH5_9ACTN -----------------------------------HRAAERFPLCSVFKTLAAAAVLRDLD -RHGETLARRIHYTAADLAGYSPKTGEHLAGGMTVGELCDAAIRYSDNTAANLLLRELGGP -TAITRFCRSLGDPKTRLDRWEPELNTAEPWRVEDTTTPGAIAGTYARLVLGDALHYRDRD -RLTTWLLGNTTSGDRFRAGLPEDWTIADKTGTGAYGTSNDVGIAWTPDGAPVALAVLSTK -PAQNAAPDSPLVAAAASVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas salina TaxID=42565 RepID=UPI0005135026 ---DLERELGELERSADDRVGVALMNVATGAVA-SHRGHERFLFNSTGKCFIAAAVLARVD -EGRETLDRRIVIEEGDLVGWTPITEKRLGEPLTVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPALNTDHAGDERDTTTPLAMMATLRTLLLGDALSPSSRH -QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTLM -PNVTGAERDETIAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0004D395B0 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGTTLHEPQRT -QLTEWMVGGARGATGIAAGVPPGWRVADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI000B79D580 ---TAQAELTTLEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFARTSGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA -RLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0007C5AEE9 ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAIQSYAPTTENLIGHYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTPDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Azospirillum sp. RU38E TaxID=1907313 RepID=A0A239KF09_9PROT ----MRKDIEALEKARGGRLGVAVLDTASGRAM-DWRGDERFAMCSTFKFLLAGHVLALVD -AGQERLDRTLPVPPKKLLDWSPATTPHAGGNMDIAALCHGIITQSDNSGANILLEATGGP -GALTAWLRQLGDTITRCDRPEPTANLVPGGELRDTTTPVSMLGLMRIILLGNALSAPSRT -QLTDWLIANTTGDTRLRAGLPAGWKVGDKTGAWDD-AANDIAIIWPKGAAPLLITSYYRQ -PDLDGKGRNAVLAEVGRIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. Leaf307 TaxID=1736331 RepID=UPI0007029136 ------AAFAALEERYAARVGVVAIDTATGETL-AHRADERFPHASTVKALAAAVLLDRTT ---PSELERVVPVRRTDLVDYSPVVEQRVGRGLTLGAAAEAAVRVSDNTAGNIVLEAIGGP -DGLRRALRGLGDRVTDPRRTEPTLNRFEPGDDRDTTTPRALATTLRTLAVDDTLAPADRR -LLLRWMSGNETGDTLVRAGVPDDWAVADKSGSGAYAARNDVAVVTPPGRAPVVVAVLTRS -EDVDAVARDALVAAAAGVVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio alginolyticus (strain ATCC 17749 / DSM 2171 / NBRC 15630 / NCIMB 1903 / XII-53) TaxID=1219076 RepID=A0A2I3CT28_VIBAX --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JCV5_SPHSX ---SAADELAGIEKASGGKMGVCVLDTATGATL-AWRADARFPFCSSFKAPLAAFVLWKAD -RGQLRLDRSIRYDAADLLSYVPITRAHVADGMSVEQLCAAAVAYSDNTAANLLLRETGGP -AALTAWMRARGDRAFNLASNEPRLNLSRYGDATDTTTARAMAESYRRFVLGDVLTPASRT -KLAGWLVANTTGDRRLRAGLPHAWRVGDKTGTFG-GSTIDIAVAWPPARPPLVIAGLITG -PN-DTASAERALVQVARTA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. WAC 06725 TaxID=2203209 RepID=A0A429IGH6_9ACTN -----VRRLRALEREHQARIGVFALNLATGASL-LHRAHELFPMCSVFKTLAAAAVLRDLD -HDGSQLARVIRYTEADVTKHAPVTKDHIATGMTIRDLCDATIRYSDNCAANLLLRELGGP -TAVTRFCRSLGDPVTRLDRWEPELNSGEPDRRTDTTSPYAIARTYQRLVLGNALNRPDRA -LLTDWLLRNTTTLTTFRTGLPKGWTVADKSGGGDYGTRNEAAIAWTPDGAPVLLTALTHK ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000A2DF188 ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0005F90F12 ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. SBT366 TaxID=1580529 RepID=UPI00066C58E4 ----FAAEFEALEQEYGSTLGVYALDTGSGDEV-AFQEGERFAFASTFKALLAGVVLSENS ---LEEMERVVTFDEEVLVPHSPVVEEHLDSGMSLLELCDATVRFSDNAAANLLLDEIGGP -AGFTERLGETGDDVTVLERYEVEMSSAVPGEVRDTSTPEAMASSLEAFTLGDVLPEDRRE -VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGNGGYGTRNDIAVLWPEEGDPIVLAVMSSV -GVEDAEHDDALIAEATEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Tatlockia micdadei TaxID=451 RepID=UPI0009EF716B ---SIDKKLAKLESSSGGRIGVYAINTTNNTHL-EYRANERFPMGCTSKVMGVAAVLKKSM -KDNLLLSKKVTYTKNDLTNWNPITEKNLDTGMSVKELCAAAISYSDNTAMNLLLKQLGGL -EGMNAFARTIDDDSFRQTHWPGEAMSGGQNNTDDSSTPAAMATSLKKLAFTDALAKPQRE -LLLTWLKANTTGDARIRAGVPKGWLVGDKTGTGYYGTTNDIAIIWPPKCDPIVMAVYYTS -NNKNTSKREDIVASTTRIILDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Prauserella rugosa TaxID=43354 RepID=A0A660CK09_9PSEU ---DVAGELAAVEQRFGGRLGVYAVDTGSGALV-QHRQRERFLMASTAKLPIVAATLGRGV -----PLDRSVPVRQEDVLEYAPVTQERAGGVMTVAELCEAAMTRSDNTAANLLTAQVGGP -AEVTGFLREKGDRVTRLDRWEPELNVR--DTRLDTTTPAAMADLTRRLLFDGGLDRAARE -QLTGWLRGNTTGDDRIRAGLPPAWQVGDKTGTGAHGEINDVAVAWPPDRAPVVVAVYTSP -RGATEEAGATALVEAARAVAGAf ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0006A5956C --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMLDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 62 TaxID=1827599 RepID=A0A3D9M7Q4_9ACTN ------ARLRRLEREHSARLGVFARDMRSGRTV-AYRANERFPMASVFKTLAVAAVLRDLD -HDGEFLARRLRYTTAYVERYSPITGRNVAGGMTVSALCDAALRFSDNTAANLLLGELGGP -TALTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPYAIGVGCARLVLGDALERHDRE -RLTGWLLRNTTSAERFRRGLPADWLLADKTGSGRHGGADDVGVAWRPDGTPIVLAVLTTK -AEEDAPADDPLVAGTAALL---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium gilvum (strain PYR-GCK) TaxID=350054 RepID=A4TCH4_MYCGI -----EERIAALAARHDARIGLYAADLDSGATL-AFGDTDTFAVCSTFKTYAAGAVLQRVQ -QGRLGLGDTVLIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRVLGGP -SAITEFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALATGYQALLTGDVLDPAGRR -QLVDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGSTNDVGIAFGPAGQRLLLAVMTRS -ASPDAPSLRPLIGELATLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria atacamensis TaxID=531938 RepID=UPI000DC42ECE ------DALVELEKKYDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MTHLDKVVTYTEADLMKSSAITKRHVQTGMKLRDLCDAAVRFSDGTAGNLLLRELGGP -AELTKYLRELGDDVTRMDRIEPAITEATPGDPRDTATPRSLGTDYQRLVLGNTLDQEKRG -FLTDLLERSVTGAKRIRAGVPQGSRVASKTGTGDYGTANDIAVVWQPNREPILIAIMSSR -SAADAKYDEALIAEAAAYVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae subsp. damselae TaxID=85581 RepID=A0A1X9U699_PHODD ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KYKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIVETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTAHEPIVVSIYIQQ -SSASMDERNKAIATIGRQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium vaccae ATCC 25954 TaxID=1194972 RepID=K0UUH2_MYCVA ------ERLHTLAQRHDAEIGVYAVDLVTQDTL-AFRADETFAVCSTIKTYIAAAVLQRTQ -TGELSLQDTVPIEPDDIRPHSPVTEPRVGTSMTLAELCQAALQQSDNAAANGLLGVLGGP -PAITAFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALGIGFRDILTGNVLEPAVRQ -QLLDWMRANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDIGVVYGPAGQQVLLSLMTKS -ASPDAPSLRPLIGELATLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000DF1F531 --------------------------LNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIV------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3B930B ---DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRXIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUY6_ECOLX ----------------------------------------------TSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Arthromitus sp. SFB-turkey TaxID=1840217 RepID=A0A1B7LLQ7_9CLOT ----YSSEFKNLEESYGAILGIYAVDTGTGNVV-SYNADERFAYASTYKALAAGAILEKYS ---IEELENIVHFTEQDVLSYAPVAKDKVSTGMTIREICEAAVRQSDNTAGNLQFDLIGGP -EGFKKSLEKIGDNITEPSRKETELNEATPGDIRDTSTPKQLALDLKEYVVGNVLSDDKKA -IFIDWMSNNATGNALIRAGAPSDWVVADKSGAASYGTRNDIAVVTPPGKDPIFVAILSKK -QGKDDKYDNKLIEDAARIVFKY- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE6D65 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGHGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012FA82E1 ---NVDRELRALEQSFDGRIGAYAVDTATGKTV-GYRAGEIFPLLSTFKAPLCAAALHRAR -TERGLMSKRVTWTKEDLKPNSPVTEKHVEDGLTVAELCEATITLSDNTAGNMVLKQIGGP -GGLTRYFRSLKDPVSRLDRWETELNDWKPGEKRDTTTPAAISRDLRAVSAGNALHPKDRE -QLNAWLVASKTGGERIRAGLPKSWTVGDKTGTNTIGGGNDIAVIWPGKSKPIIMSVYTTR -ETP--AVDNTVLAKTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Actinosynnema pretiosum subsp. pretiosum TaxID=103721 RepID=A0A347Q2T1_9PSEU -------AFAALEQRFDARLGVYALDTGSGRVV-AHRADERFAYASTFKALAFGALLAERS ---VADLDERITFTGEELVTYSPITEGKVDTGMTLREVADAAVRHSDNTAGNLLLRELGGP -AAFERALRAIGDTTTSPARVETELNEAVPGDPRDTSTPEALAADLRRYAVADVLADDRRE -LLVSTMRANTTGDEAIRAGVPLGWVVADKTGSARYGGRNDIAVLWPPDRAPIVLAVLSGK -ATADAEHDDALLAEATRAVVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Geodermatophilus sp. Leaf369 TaxID=1736354 RepID=A0A0Q5VBG7_9ACTN -------GVADLEAAHGARVGAWVLDTGTGQVL-EHRAEERFAHASVLKLLLVGLVLDRVT ---DAELDAVVPIEADDVLEYAPVTSEHVGTGLPLREVMEAAIVVSDNTAANLLIERLGGP -AAVQAAVRELGNEVTDVDRTEPDLNEATPGDPRDTSTPAALGASIEQLVLGDVLPADRRA -LLEQGLRDNTTGDAAIRAGVPADWTVGDKTGSGGYGTRNDAGVVWPADGAPLVVVLLTDR -GTAGATSDDGLLADVTRLVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A3R9D3X8_PSEPU ------QAAKEAERALGARVGYAIHDTDNGRTW-QYRADERFPMASTVKVLVCSALLHQGP ----VSLARTVHIQEHDILPYAPVTQGMVGEDVSASRLCAITLETSDNTAVNGVLKALGGP -ATVTAFLRSIGDQTTRADRSEPELNEGRPGDERDTTSPQAMQRTLEALVLGTALDKAAQA -QLTRWMESNKVSGTLLRNGLPNDWRIADRSGSGGFGSRGVVAVMWPPGRGPIVAAIYLTQ -TQATLEQQDAAIAAIGRSL---- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. 62 TaxID=1827599 RepID=UPI000E226833 ------ARLRRLEREHSARLGVFARDMRSGRTV-AYRANERFPMASVFKTLAVAAVLRDLD -HDGEFLARRLRYTTAYVERYSPITGRNVAGGMTVSALCDAALRFSDNTAANLLLGELGGP -TALTRFCRSIGDRVTRLDRWEPELNSAEPWRVTDTTSPYAIGVGCARLVLGDALERHDRE -RLTGWLLRNTTSAERFRRGLPADWLLADKTGSGRHGGADDVGVAWRPDGTPIVLAVLTTK -AEEDAPADDPLVAGTAALL---- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D0533C8 ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAAGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ITM-2017-0098 TaxID=2099692 RepID=A0A2S9FC79_9MYCO ----VEQRIDALGRRHSAQIGLYAIDLGSETSL-AYRDTESFAMCSTFKAYAAGATLQRAQ -QGRLTLNDAVAIEPGDIRPNSPVTEPRVGTTMTLAELCQAALQQSDNAAANGLLRVLGGP -PAITEFARSIGDDRTRLDRWETELNSAVPGDPRDTSTPRALGDGFRALLTGDVLDGGRQR -QLVDWMLGNQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQRLLLAIMTKS -ATPDAPSLRPLIGELAALVLA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFCA8C ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Geodermatophilus sp. Leaf369 TaxID=1736354 RepID=UPI000A71BB50 -------GVADLEAAHGARVGAWVLDTGTGQVL-EHRAEERFAHASVLKLLLVGLVLDRVT ---DAELDAVVPIEADDVLEYAPVTSEHVGTGLPLREVMEAAIVVSDNTAANLLIERLGGP -AAVQAAVRELGNEVTDVDRTEPDLNEATPGDPRDTSTPAALGASIEQLVLGDVLPADRRA -LLEQGLRDNTTGDAAIRAGVPADWTVGDKTGSGGYGTRNDAGVVWPADGAPLVVVLLTDR -GTAGATSDDGLLADVTRLVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia reimsis TaxID=2234132 RepID=A0A365QSU5_9BURK ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPDWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. Marseille-P9652 TaxID=2654950 RepID=UPI0012E80F22 ----VYDRLDRLEREYDAQVGVFAADAATGRAV-AHRDGDPFAMCSTFKAYAVARVLQLAQ -RGDVDLRQPVVIDPAKLLPNSPVTESRAGGTMALAELCAAALQRSDNAAANLLLQTIGGP -SAVTEFARSIGDDRTRLDRWETDLNTATPGDPRDTSTPRALGEGIQSLLTATVLGEAQRR -QLEDWMRANVT--STMRAGLPPGWTTADKTGSGAYGSTNDVGIAYGPDGRRVLLALMTRS -ASANAAPLPALIAEVTRAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000A2DC79C ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAIQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD -RLTDWLRHNEVGGPLLRAGVPESWNVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia sp. Hz 6-5 TaxID=2587813 RepID=UPI001390FAC5 ---SITESFEELESRYDARLGVHAVDTGTGEEV-TWREDERFAYASTIKALAAGAVLDEVG ---VAGLETEVLVEEEDIVPHSPVTENHIGQTLTLREIAEAAVTVSDNAAANYLFDELGGP -DELDAALEDLGDDVTEVVRREPELNEATPGDDRDTTTARAITGSLREYLFGTVLDDEEKS -QLGEWLIDSETGATLIRANLPSDWTIGDRSGAGGYGTRGNIAAIWPTSGDPIVISVLSSR -DEPDAEHDDQLIAEAAELAIS-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A419YPL9_9ACTN --dDLDSRLRGLERAHGARLGVFAHDTGSGATI-RYRADERFPLCSTFKPLAVAALLRAGV -----DLAATVRYTDRDVVDHAPVCG--LTRSLTVAELCAAAVEFSDNTAANLLLRLLGGP -SAVTRFCRSIGDPVTRLDRWEPALNSAEPGRPTDTTTPAALGRSYARLVLGSALAPPDRA -RLTAWLLGTTTGAARLRAGLPPTWRVADKTGTGGYGTTNDAALAWPPHRAPVVVTVLATK -PDPGAVADEPLLAAAAGSVA--- ->[subseq from] Beta-lactamase class A n=3 Tax=Burkholderia TaxID=32008 RepID=A2WFD7_9BURK ---AAQSALAALEQASNGRLGVAALDTSNGTRI-AHHARQRFPLCGTYAVVAAAAMLARAS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIAQLCVAMLQAGDKGAGNLLMGVLGGP -QAVTSFARESGDTTFRLDHWEPELNRAVPDDERDTSTPVAMVDTLQRLLLGEVLHEPQRT -QLTEWLTDSARGTPGIAAGVPPGWRVAGKTGTGGYGTTTDVAVVWPPSRAPLVMAVSFTQ -PRADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Microbispora bryophytorum TaxID=1460882 RepID=A0A544XYJ9_9ACTN ---DVAAALRALETSFKGRIGAYAIDTATGKTV-GYRAGERFALLSTFKAVAAGAVLAKTT --DRELTRKVVHWTAGEVKPNSPETSKHVKDGMTLAELCRAAIIYSDNTAGNMLLKRIGGP -RGLTRYFRTLKDPLSRLDRWETELNDWSPKEKRDTTTPASVARDLRALTTGGALGAKDRS -RLIGWLRGNTTGDARIRAGLPKTWIVGDKTGTGGYGAANDIAVVWPAKGAPIVMAISTNR -RAAAGATDDKVIAKTATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000756F38F -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVIAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGNTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Endozoicomonas atrinae TaxID=1333660 RepID=UPI000825F925 ------ELISDLENRYEGQIGVAVLDTSDQSLW-HYQGNTRFPLMSTFKTLACAKLLADVD -QQKQKLTTESLIERESLVTYSPVTEPLVGQKITLEQACEATMSTSDNTAANLVLAGIGGP -QKLTDFLRSAGDSITRLDRIEPELNESHPGDNRDTTTPLAITNTLNQLILGNTLSDVSRA -QLKTWMMGNQVADNLLRSVLPEGWSIADRSGAGGHGSRGITTIVWSKKRLPLIISIYMTG -TNASFEERNQVIVKTGQAVFHHf ->[subseq from] Beta-lactamase OXY-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644SR34_9ZZZZ --kDLQRMLAELEASSGGRLGVAASVSNGDKIL-SYRGNERFPMCSTFKVLAAAAVLRDKT ----NILEQRIHFAKSDIQPWSPVTEKHLEDGMTVSELCEAMLQHSDNTAANLVLAQLGGP -AGLTSIARSFGDTTFRLDRWEVELNTAIPGDARDTTTPLAMRRTLNGLLCGNQLKALAKK -QLTDWMLGCATGAGRIPAGAPQGWRSAHKSGSGENGTANDVGVLLPPKNKPLTVALYLTG -SRLTGPENDKILAQATRLVC--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A3B7QVI9_STRFR ----LTGQLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD -RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP -TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE -RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAILSTK -LDPQGPTENPLVARAAALVA--- ->[subseq from] Beta-lactamase n=2 Tax=Acidocella sp. MX-AZ02 TaxID=1214225 RepID=K5YKI9_9PROT ----ATSFLAESERKTGGRIGVHARNLATGRTL-SWRADERFVMCSTFKMSLVACVLSRVD -KGDEQLGRFVHYGVAQISNYAPVARLHLAEGMTVEAMCQAAIEVSDNTCADLLLMSVGGP -AALTRFWRGEGDEVTRLDHTEPRLNFSPPGDPRDTTTPAAMAGDLQRFLLGDALSPTSRA -RLTGWMLNCQTGGALLRAGLPKGWEVADKTGNNGKDALGDIAVAWPAPDRPIVICAYTQG -GHPKPEILPPILAGVGRMV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D007258 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. GXS13 TaxID=1730094 RepID=A0A0V7Z424_9RHIZ ---ETEPALDAIERRLGGRLGISVG-TPERILI-SHRAGERFPMCSTFKVLAVAAVLARVD -ARSESSDRVIAFGPGDLLSYAPVTRKALDAGMTVSDLCAAAIEWSDNSAANLLLTALGGP -RALTQWLRGFGDPITRLDRTEPTLSTSLPGDPRDTTSPAAMRETLGRVLLGSALSPSARA -RLEAWMVASRTGLKRLRAGLPPDWPVGDKTGTGDNGTFNDVAILRPPGHAPVFACVYITG -AEAPAEAVEAAYAEIGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodovulum sulfidophilum TaxID=35806 RepID=A0A0D6B6M1_RHOSU ---TLADTVERVESRLGARVGVSLVDTGSGLSW-THRENERFLMNSTMKVPLCGAVLARRD -AGDLSLQAELPVRKSDLLAYAPVTEKRAGGEMTIAELCLAAIDMSDNTAANLLIAHLGGP -QAVTRFFRSAGDTISRLDRNEPELNTFNAADLRDNTTPAAMTETLRGLLLGDILSRSSRG -QLAEWMSHGGVTGNLLRAEAPEGWVILDKSGSGTH-TRNLVALVTPVDGSPWIVTIFVSD -VDADSQTRNRALQDVGRAAM--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-1496 TaxID=1772284 RepID=A0A101AKG1_9MYCO --------VENLERANNAVIGVFAQNLDTGRTV-AHRAQESFAMCSTFKAYLAAQILQLVG -RGERSLDQRLSVNAADLQPNSPRTEPRVGGEMTLTELCQAILQVSDNAAANILLRNVGGP -PAVTAFARGIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALAGGFRAILTGEALAPPQRR -LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTKT -ATPDAENMRPLVGEVTAAVF--- ->[subseq from] Beta-lactamase n=1 Tax=Sagittula sp. P11 TaxID=2009329 RepID=A0A2K8WAW1_9RHOB ---TLSDTVAQVEERLGARVGLSLVDTGSGLTW-AHREDERFLMNSTVKVPLCGAVLARRD -AGELSLAEALPVTAEDIVSYAPVSEQKVGQTMTLAELCLATIDISDNTAANLLIGRLGGP -EAVTQAFRDSGDEVSRLDRLEPGLNAFAPGDPRDTTTPAAMSATLSRILLGDVLTAESRD -QLSDWMSYGGVTGALLRRDAPESWQIFDKSGAGTH-TRNIIAVVIPDDASPWIVTIFVSD -TDADFDTRNAALQEIGSAVM--- ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=UPI00080B6BE7 ---RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGTAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841FD1F -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPMTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A5N5V9I5_MYCPH ------TAIRALEQRHNARIGVYAVNLATGRTV-THRAQEPFAMCSTFKTYAAARVLQMAE -RGELSLTDPVFVDPAAIVRHSPRTEPRAGGDMTLDELCQAALQISDNTAGNLLLQTIGGP -QAITAFARSIGDERTRLDRWEIALNSAEPGDPRDTSTPEAIGGGYRALLTGDALGAPQRE -LLVRWMRANET--SSMREGLPAGWTTADKTGSGDYASSNDVGVAYGPRGERLLLALMART -AGPDAPTLRPVIGELAG------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 3519A TaxID=2057184 RepID=UPI000C7C68F9 ----VADRIAALERRHNAYIGVFAVDLVGGRSF-SHRGQQPFAMCSTFKAYAAGLVLQMVE -QGQLTLDQQVFVDPAGVVANSPRTEPRAGGSMTLDELCQAALQVSDNTAGNLLLTTIGGP -PAVTAFARSIGDQASRLDRWETELNSAIPGDPRDTSTPEALGGGYRTLLTGAALAPPQRQ -QLEDWMRANET--SSMRAGLPQGWTSADKTGSGDYGTANDVGIAYGPEGQRLLLAMMTRS -QL-SDPQAASMRPEIG------- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00137C15E4 ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAVQSYAPTTENLIGHYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIASIGKVIAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8JQQ9_9ACTN ----VRAELRRLEASYQGRIGAFAIDTGTGKTF-GHRAGERFPSNSTFKAVLCGAILDKAR -TDPGLMKRVLRWTKKDVVDHSPVSGENIRNGMTPDRLCHATITQSDNTAANVLLKQIGGP -AGMTRYYRSLGDRAGRLDRWETELNDWKPGEKRDTITPASMARDLKKITVGDALVAADRK -RLTDWMRATETGKERIFAGLPKGWTAGDKTGTGGYGTASDIAIAWPPSGAPVIIAVYIQR -PSADAEVDNGVIARTASLLV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces alfalfae TaxID=1642299 RepID=A0A1P8TUL4_9ACTN ----LTGQLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD -RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP -TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE -RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAILSTK -LDPQGPTENPLVARAAALVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000752A9DD ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPARAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00016A59EE ---AAQSQLDALEQASNGRLGVAALDTVTGARI-AHRSRERFPLCGTFAVVAAAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQSGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGSANGVAGIRTGVPSDWRVAAKAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PGADAAPRADVVAEAAR------ ->[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3G6HIJ0_ALCFA ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEVVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTSDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4V2YYD4_9PSEU -------NFAGLEHRFHARLGVYAVDTGTGETI-AQRADERWAYASTHKVFSAYAVLRRNT ---VEGLQRRIHYTREDLQPYSPVTEQHVDTGMTLREVVVAAVRDSDNTAGNLLFRELGGP -AGLQQELRDLGDTTTHVDRIETELGETAPGDIRDTTTPRAFAADLRKVALGDALPADKRE -ILLSAMRNSPITTKLVQAGVPADWQVEDKSGSADFGTRNDIAVVRPPGRAPIVIAVMSDR -ADRDASYDDALVAEATRLAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI00112DACC1 -----RSELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQAGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSHVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea albida TaxID=65499 RepID=A0A1H9JTA7_9PSEU ------DALVDLEKKFDARLGVFAT--GGRGTV-EHRADERFAFCSTFKGLAAAAVLHRNP ---MAHLDTVVTYTEAELMKSSAITRQHVRTGMKLRDLCDAAVRYSDGTAGNLLLREAGGP -AALTGYLRELGDTETRVDRIEPDLTSAVPGDPRDTATPRSLGTDYRRLVLGDALEPPKRD -FLVDLLERSVTGAKRVRAGVPEGSRVASKTGTGSYGTVNDIAIVWPPSGEPLLIAIMSSK -ASADAEYDEALVAEATAYVVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas prati TaxID=1843237 RepID=UPI0012F690A1 ---ALRATLAGLERQSGGRLGVAVRDRATGGVF-GYAADAGFAMCSTFKAPLVAAILHRVD -QGRERGDRAIAVGRDDIVPHAPFCETRVGARATVAELCEAAIVLSDNSAANLLLPIVGGP -GGLTAFLRRTGDPATLLDRIEPALNSATPGDPRDTTTPAAMAASLDRLALGPVLTPASRA -MLTGWMAASRTGLGMLRAGVPRDWRVVDKTGRGQTGTSAVIGVLWPPARAPMVIASYLTE -AKIEGAAADGVHRDVAQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000587CDF3 ---SVVQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASTSKLVICAALLARGP ----GAMKAAWRVRQEAVLSYAPTTKDRVGEQIPADQLCAITMRNSDNTAANGVLEILGGP -AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAAGRD -QLIGWLRRNEVGGPLLRAGVPERWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TQASMDERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=G5DDT2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAHTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGG-------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Veillonellaceae bacterium TaxID=2049049 RepID=UPI0011C79524 -------TFTRLENDHQAKIGVYALDTESNKEV-SYHADDRFAYCSTSKVLMVGAVLRQES ---LEGIKKTVSYTQKDVLSYAPITSKYVETGMTLEELCVAALRVSDNTAANLLLAHIGGT -EGFKMSLRQIGDMVTEPARNEPMLNEAVPEDLRDTSTPHQLAVDFQSYILGDILTSEKKM -MLISWMAGNKNTDTLIRAGTPTDWLVADKSGTGGYGTRNDVAIITPPGRKPIILAILTTH -NDKELKADDQLVADIAKIVCEQf ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=A0A1B1LEU7_BACTU --------LSGLEEKHDARLGVFALDTGTNQMI-TYNGDDRFAYASTHKALAVGALLQTKS ---LADLDQIITYTQKDLDQYHPITEKYVNTGMTLRDLCDAVLRYSDNTADNLIFKLLGGP -SGLEKVLRGIGDTVTNPKRIEPELNVLLKGETQDTSTPKAMAANLQAFTLRNALSEEKRA -LLLDWMKRNTTGDEAIRAGVPAGWEVADKTGKGSYGTRNDIAVIWPENGKPIILAVMSDR -NSENASSTNELIADATKEVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI000D58768F ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLTLNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGS -AALTAYLQSIGDNVTRLDRNEPTLNEAVKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSVFDTf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI0011B4F626 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPSDVRDTTTPNTMVKTLNELVYGNVLSEASKA -QLKTWLKDNKVSDGMIRSILPDGWKIADRSGAGAYGSRAITAIVWGETRAPLIISISLTE -SELTIPERDTVINEIGELIFDDy ->[subseq from] Class A beta-lactamase n=1 Tax=Agrobacterium sp. MA01 TaxID=2664893 RepID=A0A5Q2R7V4_9RHIZ ------AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD ----AVLEQTTRITKADLRPHSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP -AEVTGFLRGIGDATTRLDRYEPEVNEAKPGDPRDTTTPEAMAQTLHRLLLDGALAPAARD -QLEAWMAANAVAGGLLRAKLPKGWTIADRGGAGGHGTRGVVALLRPPQGAPLVIAIYMDG -RKHPLKTRDAAIAEIGEAVFEEf ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0005D88A7A ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGTAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Pusillimonas harenae TaxID=657015 RepID=UPI001021262C ---ALNQALVELERTSRGRIGVGLLDTASGQVT-SYRGDERFLMLSTFKTLAAAYILARSD -QGVDKLTRRMSITDADILEYAPVTRRHIGPQMTLAELCHATITTSDNTAANLMHRSYGGP -QALTQFIRSLGDTVTRHDRYEPELNKPNASEPMDTTSPNAMTSTLNTLLFGTALKPESRQ -LLQSWLKANTTGDRRLRAGIPPNWIVGEKTGTASI-GANDAGFVQAPGGAAVIASVYLET -DAIAGPERDQIIATVGKRVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A3N7RQT7_9BURK ---AAQSQLDALERASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAVAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEATLQFGDKSAANLLMSVLGGP -QTVTAFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANSVKGIRAGVPSDWRVAGKAGTGGYGTTTDVAVLWPQSHAPLVIAASFTQ -PGADASPRTDVVAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium acapulense TaxID=114977 RepID=UPI000749C9A8 ----IEDRLGEMERRQNALIGVFATNLGTGRTI-ANRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEPGDLVPNSPVTEAHVGQTMTLAELCQAALQRSDNAAGNWLLRVIGGP -SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAIGNGYRAILTGNVLAEPQRR -QLEDWMRANQT--SSVRPVLPPDWATADKTGSGDYASTNDVGIAFGPAGERLLLAIMTRT -AAPDVPNDRQLVGEVASVLV--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. VPAP30 TaxID=1647102 RepID=A0A0H2MRE8_9VIBR ---AVEKAIERQEETLSARIGVAVLNVETGALW-SFRGDERFPLTSTFKSIACAKLLYDAD -QKTTELKKTVTVNREGLVAYSPVLEAYIDKEITLGDACQATMLTSDNTAANIVIASVGGT -DSITSFVRELGDENTRLDRVEPELNEALPNDPRDTTTPISMTNTLNELVFGAVLSENSRA -QLIDWMKSNEVTGNLLRSVLPVGWEIADRSGAGGFGARSINAVVWLDKKSPIIVSIYVSQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000751BC02 ---RAQSGLAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIEWMTASAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000E1C7F3B ---ALVDIIKQQENALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKLALTYQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDLRDTTTPIAIVETLNKLMLSDILTKPSQQ -QLITWMEGNQVAVPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. XS-10 TaxID=2599297 RepID=A0A518RKR2_9SPHN --------FDRIRAETGGRLGVAVYDTGTGRRY-FDGAEARFAMCSTFKVPLVAAVLARVD -RGELDLAREIRFSAADLLSYAPVVKENLAKGLSIEALCEAAVVMSDNSAANLLFGQIAGP -RGLTKFIREAGDTITRSDRDEPELNNVRDGEVRDTTTPEAMLWLMNRLLLGDILSAASRA -KLIGWMEASPTGKDRLRAGLPRSWRVGDKTGTSGEGYFNDIAIATPPGRKPVLITCYLDA -PGLDAAKANAAHARVGELVG--- ->[subseq from] Beta-lactamase,beta-lactamase TEM,Beta-lactamase n=1 Tax=Burkholderia stabilis TaxID=95485 RepID=A0A498RS12_9BURK ---TAQAELAALEKASNGRLGVAALDTSSSVRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMGVLGGP -QAVTAFAHDSGDPTFRLDHWEPELNKATPGDERDTSTPVAMVDTLQRLLLGDTLREPQRA -QLTEWLTGGARSAAGIAAGVPSGWRIAGKAGTGGYGTTTDIAVVWPPSRAPIVMAVSFAQ -PQADAAARADVVASAARIVTGAf ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=A0A107FUA6_9BURK ---AAQSQLDALEQASNGRLGVAALDTATGARI-AHRSRERFPLCGTFAVVAVAAMLARSA -LDASLLPRRILYRRYELVPGSPVTERHADTGMTIGQLCEAMLQFGDKSAANLLMSVLGGP -QTVTEFAHASGDTLFRLDRWEPELNTARPDDERDTSTPLAMAETMRRLLLGDTLGAPERA -QLTKWLLGTANSVKGIRVGVPSDWRAAGKAGTGGYGTTTDVAVLWPPSHAPLVIAASFTQ -PGADAAPRADVIAEAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizomicrobium electricum TaxID=480070 RepID=UPI00142314B1 --------------DTGGRLGVSVLDTGSGKRL-RHRATERFAMCSTFKLLLAAAVLKRID -TGKEDASRVIAYSKADHLVWSPVTEKHTA--LPVTDLVDAIVQVSDNTAANLLLDTIGGP -AGWTAFVRGFGDKTSRLDRTELTLNNADPGDPRDTTTPDAMLENLQKVLLGDVLTPASRQ -HLIDTMARSITRIKRLKAGLPKDWRIADKTGTGKHDTYNDVAIIYPPGRAPILACAYYTE -ATR--PDPENTLAEVGRAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes sp. EGD-AK7 TaxID=1386079 RepID=U1YEP2_9BURK ----VAQAAQAVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQYVPASQLCAITMRNSDNTAANGVLEMLGGP -EAITSFLRSVGDMVTRLDRNEPSLNEARPGDPRDTTSPQAMVHTLQSLVLGDALKAPDRD -RLIDWMTHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbidospora sp. NEAU-GS84 TaxID=2696284 RepID=UPI001372D303 ------ADLRALETAFKGRIGLYALDTATGRTV-AYRSGERFPLASTFKGVLAAAVLDKKP ----DILGKRILIRKKDLLPNSPETAKHVGSRMTVAALARAAVTKSDNAAANLLLRQIGGP -KGLTGYFRSLDDHVSRLDRNEPGLNLWHPREVRDTTTPAAIAADLKALTVGGALDAGDRR -TFTGWLVANETGDKRIRAGLPKSWRIGDKTGTGGYGTANDYAVIWPKGSKPIIMAIYTNR -TDRNAAADESVIARAATIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI000F5E16D0 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTSAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium hodleri TaxID=49897 RepID=A0A544W081_9MYCO -----GDQFAALERRYDAFIGTWAADLDGGRSV-ANRADDPFAMCSTFKAYAAGRVLQKDQ -TGALHLTDAVTIEAVDLVANSPITEPRVGQNMTIGELCEAALQRSDNTAGNWLLRIIGGP -SAVTTFARTLGDDRTRLDRWETDLNSAVPGDPRDTSSPRALGAGYQRLLTGDVLDAPRRA -QLERWMRGNQT--SSLRAGLPAGWTSADKTGGGAYGSTNDVGVVYGPDGRRLLLSIMTRS -RTDDAHDLRSLVAEVTTLVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SDr-06 TaxID=2267702 RepID=A0A367HX57_9ACTN ---DVADELRRLETAQHVRIGAYALDTATGRSV-SYRGNEKFPSLSTFKAMVCAAVLGRAR -HEPGLLDKVVHWKASQEVANSPVTAGQGGKGMKVADLCHAAVTRSDNTAGNLVLGRIGGP -EGMTRYYRALGDAVSRLDRWEPDLNVWKPGEQRDTTTPAAMGRDLARTSLGSALVPADRA -RLNSWLRATVTGNERIRAGLPKDWTVGDKTGTSDYGSANDIAVAWPKSGRPVIIAIYTNH -LTADAPADSAVIASTTSTLV--- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A5B0EUD5_9PSED ---DIEIQLQKLEREHGGRLGVALMNCSTGAIA-SHRGNERFLFNSTSKLFIAAAVLARVD -SGEETFDHRLVVSESDLGGWTPITEKQLGEPITVAELCQAAVAWSDNAAANVLIRSVGGP -EAVTAYLRSISDDTTRLDRYEPDLNEDHEGDERDTTTPLAMMKTLQLLLLGEVLLPSSRH -QLAAWMIEGKTGGARLRAGMPASWLVGEKTGTNGVGNANDIGVAWPADRGAVIAIAYTFM -PNASKEQCDKAIALIGKIAS--- ->[subseq from] Uncharacterized protein n=3 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A656TCP1_9PSED ---------ASIEARTGGQIGVSVTALESGQSW-SHRGDERFPIASTFKAFSCGHLLALAD -RDKIELDTRVRFDETDLQSYSPITKDRVGGSMSLFELCSATTSMSDNTAANLILRHTGGP -LGFTTFMRSIGDAVTRLDRYEPELNDVGPGEERDTTTPMAAARSLETLLLGDSLSTHSRE -QLKAWLINNKVGGPLLRASLPESWKIADRTGSGGYGSRGVIAVIWPQGSEPVIVAVYLTG -TTLTLEERDATIAEVGAALV--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL120 TaxID=2603887 RepID=A0A5C8RVZ2_9RHIZ ---SAAARIAAVEARLGGRVGVAFRD-ASGVFL-GHRAGEAFAMCSTFKVLAAAAILARAA -AGAETLDRRIAYGAADLQSYGPVTRAALANALTVEALCAAAIVWSDNTAANLLLDALGGP -AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPSAITGTLERCLLGDVLTPPHRA -RLEGWMVACETGRTKLRAGLPLDWTVGDKTGSGDNATSNVVAILHPPGRPPILAGLFLTG -SAPPPATRDAAHAEIGRILVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D005A0A ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAL -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD4A702 -------AAQRVETELGMRVGFAVLDTGSGEVR-RYRANERFAMASTFKALACAAALSA-- --GPSVLDKQTRISKADLRPHSPVTEKRVGTGLSTRALCEITLRTSDNAAANAILKAIGGP -AAVTTFLRGIGDDTTRLDRYEPELNEATPGDPRDTTTPQAMAETVGRLLLDRALEPKARD -QLEAWMAANAVAGGLLRAGLPKGWAIADRSGAGGHGTRGVIALLRPPEGAPLVVAIYMDG -RKHPLKVRDAAIAEIGAAIFAEy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SH65_9BACT ---TLSKAVQAEEARLAARIGVALFDAKDGTRW-AHRGDERFPLNSTHKSFSCAALLKQVD -RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP -QAFTVFMRDIGDQHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA -LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKNRAPIVVGIYITQ -TTAPMVDSNAAIARLGSVLAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. P44RR-XXIV TaxID=1921145 RepID=A0A4V6UGD2_9RHIZ ----QQQRLAALESKHPGRICVSILDLASGRRI-EHRAGERTLICSTFKTLIAALVLTRVD -KGEEKFDRRIRYSKSDLVESSPATGAQLENGMTIAQLCAAAMTLSDNTAANLLLASFGGP -KALTAFCRSLGDDITRLDRTEPALNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSAASRS -QLAAWLITNKTGDTRLRAGVPKDWLAGDKDGNAN-----DIAVLWPTNRAPIIVTAYCEI -PGIPADERNSIIAEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3D8EDE ---DLESRFAELEQKYEARLGVYVPGTGATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLDTVITYNSADIRSTSPITEQHLETGMSIGGLCDATIRYSDGTAANLLFQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALPPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRXIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Agrobacterium TaxID=357 RepID=K2PB25_9RHIZ -------AAKRVEERLGMRVGLSVIDTGRGTVV-AYRETERFAMASTFKSLACAAALAGGN ----AVLEQTTRITKADLRPHSPVTEKRVGTNLSTRALCEITLRTSDNAAANAILKTLGGP -AEVTGFLRGIGDKTTRLDRYEPELNEATPGDPRDTTTPQAMAQTLEHLLLGDALAPAARD -QLEAWMSANAVADGLLRSKLPKGWQIADRSGAGGHGTRGVIAVVRPPPGQPLVIAIYMDG -KTHPLKARDAAIAEIGDAIFARy ->[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas sp. NBT06-2 TaxID=2025950 RepID=A0A269PKC3_9GAMM -------IIEEQEHQLGARIGVSIYDVIDNKLW-NYNGNTRFPLMSTFKVLACAKLLADVE -KGLQSFDTSLVITASSLIKWSPITKNLIGKKMSLKQACSAAMIMSDNTASNMVLNGIKGP -KALTQFMRNIGDEVTRLDRIEPDLNEALDGDKRDTTTPNAMVKSLHKLLFGDALSQASKN -LLKQWMIDNKVTASLLRSILPDNWLIADRSGSGGYGSRGIVAVAWSDKRTPIIISIYLTQ -TDAPFSLRNKAIADIGKEIFTVy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A1Z3Z0C0_BURCE ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELTHAAPGDERDTSTPVAMIDTLQRLVLGNTLPEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium bacteremicum TaxID=564198 RepID=A0A1W9YVI8_9MYCO ---SLPEQFRELEARHNAFIGVYGVNLDSGSSV-RNRPDEPFAMCSTFKGYAAAAVLRRVA -EGELSLDKPVFVDPAGILPNSPVTEERAGGQMTLAELCQAALQRSDNLAANLLLATLGGP -RAITDFARSIGDDKTRLDRWEVELNSAIPGDPRDTSTPEALGHGYRNLLAGTALPPAQRD -LLDGWMRANQT--SSMRAGLPPDWTTADKTGSGDYATTNDVGVAYGPAGTRVLLSIMTRT -QSADAEGLRPLIGEVAALVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A411T593_ALCFA ---SVVQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASISKLVICAALLARGP ----GAMKAAWRVRQEAVQSYAPTTKDRVGEQISADQLCAITMRNSDNTAANGVLEILGGP -AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAADRD -QLIGWLRRNEVGGPLLRAGVPERWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TQASMDERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A0M1F3U4_STEMA ------ADFAALEKASGGRLGVTVLNTGNGRRIgGHRQDERFPMCSTFKSLLVAHVLSLAD -AGRVSLDTRVPIAGKDLLSYAPVARRHVGKDLTVRDLCRGTLTTSDNTAANLLLEVVGGP -SALTAFLRGQGDSITRNDRNEPDVNLFVKGDPRDTTGPAAMATSLARFAVGNGLQPASRQ -QFADWLIDNQTGDACLRAGLGTRWRVGEKTGSNGDDTRNDIAVLWPHGGAVWVVTAYLQG -ASVDYDQRAAVLARVGAL----- ->[subseq from] class A beta-lactamase n=1 Tax=Halomonas sp. HG01 TaxID=1609967 RepID=UPI0006148262 ---DLERELGELERSADDRVGVALMNVATGAVT-SHRGHERFLFNSTGKCFIAAAVLARVD -EGSETLDRRIVIEEGDLVGWTPVTEKRLGEPLMVAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLRAIGDDTTRLDRVEPALNTDHPGDERDTTTPLAMMATLRTLLLGDALSPSSRH -QLASWMIEGKVGDARLRAGMPSSWLVGEKTGTNGVGNASDIGIAWPGDRGAVIAVAYTLM -PNATGAERDETIAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000D3C0E9C ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIGGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=UPI000AB9FE82 --------IAAYEKATGGRIGVYACNLATRQRL-TWRENDRFALCSTFKASLVALVLLRVE -QGKDRLDEAVPYTRADIERYAPVAQASLEAGMSVRALCQAAIEQSDNACANLLLARVGGP -ENLTRFWRSLGDQATRLDDWEPDLNRVPPGSVRNTTTPAAMAGVLEHLLFGNVLSASSRL -VLTEWLKRCQTGRNRLRAGFPAGWEVGDKTGTNGQDAAGDSAVAWPSPRTPLIVCVYTRG -GHPAEDQFRAAFAGIARLA---- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=Q3S672_ECOLX --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKTDLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLRSVLPAGRNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGHSIFDVy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU15512 TaxID=2015345 RepID=A0A228GIW2_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFVRASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLVLGNTLQEPQRA -RLTEWMAGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0010FEE44C ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKLVLTHQVVIKKSELVTYSPVTEKWIGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSDILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTQHKPMVVSIYIQQ -SSASIDERNKAIAIIGKQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium psychrotolerans TaxID=216929 RepID=UPI00138D666C -------DLKGIEHRHRARIGAYAVDLGAAATV-EHRADERFAMCSTFKAYAAGRVLQLVD -QSRLDLRTPIPVNAADIVANSPVTEQRVGATMALAEVCEAALTRSDNAAGNLLLRTIGGP -GGVTAFARTLGDEQTRLDRWETELNSAIPGDVRDTTTPRGLCWGYRQLLTGTALSPSARA -TLDGWMRANVTSGPRFRAAVPAGWTTADKTGAGDYGSTNDAGLILGPARQRVTAVVLTRS -IDKDTPPLNAAISDTVRLILDSf ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium florentinum TaxID=292462 RepID=A0A1X1TVY8_9MYCO ---QVDDRLAELERQYDAYIALLATDLGSGRTV-AHRDDDPFAMCSTFKAYAAARVLQKVQ -RGELDLQQRVFIDPAALLPNSPVTAPQAGNTMALAQLCAAALQRSDNVAANLLLAQIGGP -PAITDFARSIGDERTRLDRWEIELNTAIPGDPRDTSTPRALGIGIQNLFTGTVLGDAQRS -QLEQWMRGNVT--SSMRAGLPPGWTTADKTGSGDYGSTNDIGMVYGPAGQRVLLSLMTRS -QSRDADALRPLIAEVTKSVF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A5Q0DMQ2_ALCFA ----VAQAAQELEQSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLVREEAIQSYAPTAEDLIGQYVPASHLCAITMRNSDNTAANGVLEMLGGP -EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVRTLQNLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea gerenzanensis TaxID=93944 RepID=A0A1M4EJS6_9ACTN ---QVKKELRALEASFKGRIGAYAIDTATGRTV-GYRSGERFPLLSTFKAPLCAAALHRAR -TEPGLMEKVVKWTAADLKPNSPTTEKHVEDGLSVAKLCEATITESDNTAANMILKQIGGP -AGLTKYFRSLKDPISRLDRYETELNDWTAKEKRDTTTPAAIARDLRLLTAGNALQAKDRE -QLNAWLIANKTGDARIRAGLPKTWKIGDKTGTNGIGGANDIAVVWPSGAAPIILAVYTHR -TV--AAADDAVVAKTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Tardiphaga sp. P9-11 TaxID=2024614 RepID=A0A5A7W9Z6_9BRAD ----APAALQTYERDTGGRIGVYAENLKTGAKI-EWRANERFVMCSTFKASLAACVLARID -RGEDKPDHMISYAAADLLEYAPVARDNLAKGLSVADMCKAIVELSDNACANMLLARVGGP -AALTAFWSRTGDSVSRLDHNEPLLNRSRPGNPQDTTTPAAMAGNIKRFVTGDVLTSASRD -RLTDWMVNCKTGDKRLRAGLPKTWKIGDKTGNNGKDAAGDIAVTWPKPDQPIVIAAYTQG -GAPTAPQFETVFKAIGEMV---- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB4 TaxID=2015566 RepID=A0A257H361_9BURK ---------VALEKKVGGRLGVAFLNTSNGAMV-GHRLEERFGMCSTFKLPLAAAVLRKVD -QGALRLDQWVAYSASDIVAHAPVTQENLAKGMTVGALAEAAQTTSDNPAANLLLGLIGGP -AGFTGMLREAGDSVTRLDRMEPHMNAVARQDPRDTTTPSAMAATLVRILTSDWLTPDSRA -KLIDWMVATETGAKRLRAGFPTQWRAGDKTGTGMMDKYNDIAIAWPQGRAPLIVTAFYET -SKKMRDQDQAVLAEVGRIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075EEA35 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTAFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. HI00D65 TaxID=1822216 RepID=A0A166AL45_9VIBR ------ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE -HKGLDLDSKVSIRSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIEGP -NGLTQFLRSIGDSHTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASTS -TLTGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIINVSLTE -TEFTLQQRDKVINEVGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium sp. Leaf289 TaxID=1736324 RepID=A0A0S9R4Y0_9ACTN ----FSADFADLEEEYDARLGVYAIDTGTGQVV-EHRADERFAYASTIKALAVGALLHEKP ---RSVLDQTVELGEEDLVENSPELEKAVEEGLTVRELADAAVRYSDNTAGNLLFDLLGGP -EELQGVLREIGDETTIVSRIEPELNEAVPGDDRDTTTPEALATTLRAFTLGDAVNNGARA -MLTDLMVRNTTGDDLIRSGVPDNWEVADKTGAAAYGTRNDIAVLRRADGDPIVLVIMSSK -TEQDAEYDNDLIADATRVAVAGf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fortuitum TaxID=1766 RepID=UPI000907F6DD ----IDDQLAELERRDNVLIGLYAANLQSGRRI-THRPDEMFAMCSTFKGYVAARVLQMAE -HGEISLDNRVFVDADALVPNSPVTETRAGAEMTLAELCQAALQRSDNTAANLLLKTIGGP -AAGTAVARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAVGYRAILAGDALSPPQRG -LLEDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAFGPDGQRLLLVMMTRS -QAHDP-KAEN------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK042 TaxID=2512137 RepID=A0A4R3FKR3_9ACTN ----APKGLRELEARHGARLGVFARNIVTGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDHA -LLTHWLRNNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL -PAQDAARDDVLIRDTAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Actinomycetales bacterium TaxID=1911520 RepID=A0A4Q5TJ04_9ACTO ----FSADFADLEEEYDARLGVYAIDTGTGQVV-EHRADERFAYASTIKALAVGALLHEKP ---RSVLDQTVELGEEDLVENSPELEKAVEEGLTVRELADAAVRYSDNTAGNLLFDLLGGP -EELQGVLREIGDETTIVSRIEPELNEAVPGDDRDTTTPEALATTLRAFTLGDAVNNGARA -MLTDLMVRNTTGDDLIRSGVPDNWEVADKTGAAAYGTRNDIAVLRRADGDPIVLVIMSSK -TEQDAEYDNDLIADATRVAVAGf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium monacense TaxID=85693 RepID=UPI0007E97D15 --------LDALERANNAVVGVFAVNLDTGRTV-AHRAQESFAMCSTFKAYLAAHVLQLVG -RGERSLEQGLYVDAADILPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRDVGGP -PAVTAFARGIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALGGGFRTLLTGDVLAPPQRR -LLEDWMRANET--SSIRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTRS -ATPDAENMRPLIGEVTAAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI00075B2D5B ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLQSGDQGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMTAGAR-GDGIAAAVPPAWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-3022 TaxID=1772277 RepID=A0A124EMB2_9MYCO -----DARIGELERQHNALIGVFAVNLDTGRTI-AHRAQEPFAMCSTFKGYAAARILQKAE -RGELALSDRVAVEQSDIVPNSPVTQTRVGQTMTLAELCEAALQRSDNAAGNLLLGVIGGP -PAITDFARSIGDQRSRLDRWEVELNSAVPGDPRDTTTPEAIGGGYRSMLTGAALAEPQRR -LLEDWMRANQT--SSVRPALPPGWTTADKTGSGDYGSTNDVGVAHGPDGRRLLLAVMTRS -AGNDAPNMRPLIGELAALLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium asiaticum TaxID=1790 RepID=UPI0007EF1E5A ---DLSHQFDQLERRYEGRLGVYVPE----PAI-AYRADERFAFCSTFKAPLAAAVLHQYP ---LDHLDKLVSYNRSDINSVSPVTEQHVDTGMTVGQLCDAAVRYSDGTAANLLLAEVGGP -AGFTAYLRTLGDNVSRLDQPEPQLNRDAPDDPRDTTTPHAIALVFQQLLLGDDLPADKRV -LLVDWMTRSTTGGKRIRAAFPPDWKVADKTGSGDYGRTNDVAVVWSPSGAPHVIAIYSDF -VGYGAQPNDAFVADAARIVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrionales bacterium (strain SWAT-3) TaxID=391574 RepID=A5KWL1_VIBBS ------ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE -NKGLDLDSKVSIKSRDLIVWSPVTKELVDKGISLRDACSATMTMSDNTAVNIVLGGIGGP -NALTQFLRSIGDSNTRFDHLEPELNHARPGDARDTTTPNSIVMTLNELMYSDTLSQASKA -TLKGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVALTE -TEFTLQQRDKVINEVGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0013EF7A68 ---SVVQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASISKLVICAALLARGP ----GAMKAAWRVRQEAVQSYAPTTKDRVGEQISADQLCAITMRNSDNTAANGVLEILGGP -AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAADRD -QLIGWLRRNEVGGPLLRAGVPERWAVADRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TQASMDERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase n=2 Tax=Listeria grandensis TaxID=1494963 RepID=W7BE56_9LIST ---DTTAQLKNLEKKYQATLGVYAIDTGFGETF-AHNGDQRFAFASTIKAFLGGILLKNLS ---WDELNKTIMYTEDDLVSYSPITEKHVDTGMALKDIISAAIEYSDNTAANLMFNQLGGP -KGFQEQLRNLGDTVTNSSRIETDLNSAIPGDIRDTSTPKTMAENLKKLLFEDKLAPDKLK -FYNQILIGNATGDTLIRAGVPANVKVGDKSGAASFGTRNDVAVLYPPHRSPIILVVYSNK -ANEDDEYDDALIADAARVMSSHf ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia phymatum TaxID=148447 RepID=B2JET9_PARP8 ----ARERFEQLEASSGGRLGVAALRTADGSYV-GYRESERFPMCSTFKLLAVALILKRSM -AERGLLEERIRYGDAQVVAHSPVTKRHAGGEMTVGELSAAALQHSDNTAANLLLTSLGGP -EVLNQFALSIGDTWFDLVRNEPEVNASVPGDMRDTTSPRAMLLDVQKLLLDDVLGARERE -QLKAWMLGNTTGATRIRAAVPAGWLVADNTGSGDYGTANDVAVVYPPSSAPLVVAIYFTG -VTKETPPQDAIVDEAARIVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium hippocampi TaxID=659824 RepID=UPI0013955A6F -----DERIEAFERQHNVVVGLSAVELPSGRWL-AHRGKERFAMCSTFKAYAAGAVLQRAD -RAELALNEAVNIEPADIITHSPVTGTRVGATMTLAELCQATLQQSDNAAANLLLRVLGGP -AAITTFARSIGDDQSRLDRWETELNSAVPGDPRDTTTPFAVGAGYRNLLTDDVLSTDGRR -RLEDWMLANQT--SSMRSGLPARWTSADKTGSGGYGTTNDVGIAYGPEGQRLLLAIMTRS -AAPDAPNQRPLIGELAALAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2L1J0W6_KLEPN -------------------------DLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGXRGARGIVALLGPNNKA---------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella enterica TaxID=28901 RepID=A0A3W2N4L9_SALER -----------------------------------------------SKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces carminius TaxID=2665496 RepID=A0A2M8LR84_9ACTN ---SVAGRLRALERAHSARLGVFALNPATGAAV-LHRADERFAICSVWKPLAVAAVLRDRD ---EAFLGRRVRYTEADLVAHSPDTGRNLANGMTVAELCEATVCRSDNTAGNLLLRELGGP -RAVTRFCRSIGDQVTRLDRWETELNSAEPGRVTDTTSPRAVAQTYRRLITGGALDEPDRE -RLTDWLRTNETNGRSFGAGLPDGWTSADKTGAGRHGSNNDVGVAWTPDGRPVVLAVLTAK -EKETAEPDYPLVAKTAELLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. AU6039 TaxID=2015344 RepID=A0A228PGL7_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDMLQRLLLGNTLQEPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=UPI00104C111F ------------EQKLAARVGYAIHDTGTGRWW-QHRADERFPMASTVKLLVCSALLHQGQ ----AALKKPWRVQQKDILPHSPVTQGMVGKQVAASDLCAATLKTSDNAAANGVLEVLGGP -ETVNTFLKEIGDQTTRSDRNEPSLNEGLPRDKRDTTTPRAMATTMQSLLLGSALKEGQKQ -QLKEWLLSNEVGGPLLRAGIPDDWQIADKTGSGGFGTRGIVAVMWPPQRAPIVAAIYLTE -TTASLEQRNAAIAEIGRAMVK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. A1499 TaxID=2563104 RepID=A0A4S3GM14_9ACTN ----LTGHLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD -RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP -TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE -RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAVLSTK -LDPQGPTENPLVARAAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1L0J9_MYCCH ---------TALEDWYGARIGVYAVDLDSLRTV-EHRADERFSMCSTFKTYAAARILQLSN -AGAADLDTKMPIARDDIVVDSPITRDAVGSSMSLGDICAVAMMHSDNTAGNIMLRTIGGP -AAITAFARSIGDTHSRLDRWEPDLNTAIPADPRDTTTPKALCTGYRRILTADVLATPARD -RLLTWMKSNVTSSKRFRAGLPPGWTSADKTGAGDYGSTNDAGLLIGPNGQRVVAVVMTRS -RDHDAPPFNEAIAGAIRV----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A127AX88_KLEPN ------------------------DNTADNSQI-LXRADERFAMGSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARHLGDQTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLPNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTLLH- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phymatum (strain DSM 17167 / CIP 108236 / LMG 21445 / STM815) TaxID=391038 RepID=UPI000A2BFC0B ----ARERFEQLEASSGGRLGVAALRTADGSYV-GYRESERFPMCSTFKLLAVALILKRSM -AERGLLEERIRYGDAQVVAHSPVTKRHAGGEMTVGELSAAALQHSDNTAANLLLTSLGGP -EVLNQFALSIGDTWFDLVRNEPEVNASVPGDMRDTTSPRAMLLDVQKLLLDDVLGARERE -QLKAWMLGNTTGATRIRAAVPAGWLVADNTGSGDYGTANDVAVVYPPSSAPLVVAIYFTG -VTKETPPQDAIVDEAARIVFD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID8499 TaxID=2706106 RepID=A0A6B3EC10_9ACTN ---RAEAQLAALERRFGGRIGVYAVDTGTGAEV-RHRAGERFLMCSTHKLLTVAAVLRARW -DRPDLLDQVVAYRSSDVIAHSPATAPHVADGMTVAALCRAALTLSDNTAANLLLRTVGGP -AAVTRLVRALGDPATRLDRTEPHVNDA--DGVLDTTTPAHLAADLRALTLGHALEARDRD -RLLAWLDASTTGDRAVRAGCPRGWRIGDKTGSGSHGESNDVAVIRPPHRAPLVLTVFTAP -ADPRSTAGQPTIAEAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51152_SCH6134967 TaxID=1834096 RepID=A0A1A2DZA7_9MYCO ----IEDRLGEMERRQNALIGVFATNLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRITIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAGNWLLRVIGGP -SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAVGNGYRAILTGNALAEPQRR -QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDFASTNDVGIAFGPAGERLLLAIMTRT -AAPDVPNDRQLVGEVASVLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=UPI000841E517 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. HI2714 TaxID=2015359 RepID=A0A228QTQ5_9BURK ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=UPI00125FEA7E ------QAAKEAERTLGARVGYAIHDTDNGRTW-QYRADERFPMASTVKVLVCSALLHQ-- --GRVSLARTVPIQQHDILPYAPVTQGMVGEDVSASRLCAITLETSDNTAVNGVLKALGGP -ATVTAFLRSIGDQTTRADRSEPELNEGRPGDERDTTSPQAMQRTLEALVLGTALDKPAQA -QLTRWMESNKVSGTLLRKGLPSDWRIADRSGSGGFGSRGVVAVMWPPGRGPIVAAIYLTQ -TQATLEQQDAAIAAIGRSL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A2S9NHU0_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIANKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora enzanensis TaxID=155975 RepID=UPI000378E193 -------ALVALEAELGGRLGVYAIDTGTGRSA-GHRADELFLSCSTHKPLVAANILHRAE -TESALLGQLIRYDRSRLLEYAPITGRHVDTGMTVADLCAAAVEVSDNTADNLLFDLVGGP -AGVTAFVRSLGDTITRLDRVEPDLNVAAPGDERDTTTPTRITRTLGKLLLADGLTQPGKD -RLIGWMVDSTTGKDLVRAALPTGWRTGDKSGSGAQGQVNNVAITWPPNGAPWLVAVFTAP -NDHDGDRTRPFVARAAKIAVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium album TaxID=417948 RepID=UPI00041416DA ----ADEQFSALEDRFDARLGVHAVDTGSGDTV-GWREDERFAYASTIKALAVGALLDS-- -KGVEVMQEEVAVEEADILEHAPVAETRVGQTMSLGEASEAALVVSDNTAANYVFDAIGGP -HALDGQLEAIGDEVTVVERDEPDLNEAAPGDDRDTTTPAAAAGSLREYLLEDALDAEERA -MLTDWMKSNQTGETLVQAGVPDTWQVADKSGGGHYGSRGDIAVVWPEEGEPIVIAVYSSR -EEQDADYDDRLIAQAAQVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Superficieibacter electus TaxID=2022662 RepID=A0A2P5GT59_9ENTR ---AITNVLQQYETRLNARIGMAVVNEHGVPVF-SWRQDERFPLTSTFKVLACAALLDKLH -KSGGSLEQTVSIQPEKLLEYSPITKNHLSPALTLRTLCSAAVSYSDNTAANRLLEYLGGP -PAVTQFMRSIDDHVTRLDRTEPTLNEATPGDVRDTSTPKNMALALHQLLASDTLSQADRK -MLDTWMRDDKVADALLRATLPAGWAIADKTGAGGHGSRAIIAAVYPPEKPPFYLAIYITQ -TNMPMKAADAAIADIGRQLFN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-1521 TaxID=1609100 RepID=A0A0X3X5K2_9ACTN ----LTGHLRALEQEYAARLGVFALDTASGATV-SHRAGERFPMCSVFKGLAAGAVLRDVD -RHGEFLGRRIRYTAEFVEAYRPVTGKNIANGLTGAELCAAAVSESDNGAGNLLLRELGGP -TAITRFCRSLGDDTTRLDRWEPELNTAEPWRTEDTTSPRAIGMTYGRLLLGRALAARDRE -RLWDWLVANTTNTERFRKGLPADWILADKTGGGSYGVANDVGVVQPPGRSPLVLAVLSTK -LDPQGPTENPLVARAAALVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Kocuria koreensis TaxID=592378 RepID=UPI001011C881 ---DVVSELRELERQLDGEIGVHAIDTSTGECF-GYRDQQPFLLCSVSKVLVVATVLNRAS -HDPKLLGRRVDITQEDILAYAPVTSKHLEDGMTVEELCAAALTVSDNTASNLLMEQCGGP -EAVTDFVRSTGDLTTRLDRIEPDLNDA--SGGLDTTTPAAFSETLNRLTLGGALSASGRD -KLVGWMKESATGAEQIRAGLPEGTLVGDKTGSGTHGESNDVAVIWPKQGGPIIMSVFTTS -SRADTDGQKAAIAGTARAVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0008421FD9 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVTAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIEWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DQK5_BURVI -----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia testacea TaxID=248551 RepID=UPI000A0297C7 ---DLSNTLMTLQAKYNVLFGIAAVDTRGGRTF-EWNADDRFAMCSTFKVYAVAAILRLAE -RRELDLNDKVPITRQDIVMNSPVSYDHIGELMSYYELSRAALVRSDNTAANLLLRRLGGP -AAVTAFARSINDSQTRLDRWEPELNEARAGDSRDTSTASAFAAGYRKLILGDGLSTEYRR -MLTSWMRSSVTSRQRLRAGLPVGWVAADKTGSGAYGTANDAGVVWGPTGTSLVLVIFSRS -TTPMAAGADAAVADAAAAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI0009E775F4 ---TLSRELVRLETAGRGRLGVALLDTASGQAA-GHRGDERFLMLSSFKTLAAAYILARAD -RGEDQLTRRIPITEADLQEHAPVTRLHVGPQMTLAELCEATITTSDNTAANLMHRSYGGP -QALTRYIRSLGDTVTRHDRYEPELNRPHAGAPLDSTSPNAMNGTLNALLFGAALKPASQQ -LLRSWLLANTTGGKRLRAGFPPDWKVGEKTGTYSKVGANDAGYAQAPGGAPILVCAYLET -TAVPMPERDGIIAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium tokaiense TaxID=39695 RepID=A0A378T8H7_9MYCO -----AERLAELERRHNAMVGLYAVDLQTGRTL-VHRENERFAVCSTFKAYLAARTLQAAA -RGEFAMTDTVTVRAEDLLPNSPVTETRVGHTITLAELCAAVLQVSDNAGANYLLHQIGGP -PAITEFARSIGDQETRLDRWETELNSAVPGDPRDTSTPTALGNGFRALITGDALEPQART -QLMDWMLANTT--SSLRPGLPADWTFADKTGSGDYGTTNDIGVAFGPDGRAVLLSVMLRS -ASPDAEGFRPVMPEIATLVLQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012613E15 ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDLRDTTTPNAINHTLNTLVLGETSSSASRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. BK042 TaxID=2512137 RepID=UPI00104C95EA ----APKGLRELEARHGARLGVFARNIVTGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGPDHA -LLTHWLRNNTTSGTRLRAGLPPAWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL -PAQDAARDDVLIRDTAALLA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Mesorhizobium TaxID=325217 RepID=A0A435F1K7_9RHIZ ------------------------------------RENELFPMCSTFKTLAAALILHRVD -GGIEQLERSIKIPHNAIIANSPTTKKFAGGEMTVAQLCEAAVTVSDNGAANLLLESFGGP -PQLTAYLRSIGDSVSRLDRIEPELNESLPGDERDTTSPLAMVEDYERLALGNSLSDKSRA -QLVEWLVANKTGDERIRAGLPKGWRCGDKTGTGDRGSTNDAAVIWPASGNPILMSVYLTG -TKQSLTKRNAVIASVSRTLVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_035 TaxID=2175673 RepID=UPI000DA72DA6 -----APAFDRLQQTYGATLGVFALDTGTRQTV-AHNANRRFAYASTYKSLAAGVLLADPS ----TDLDAHVDLAQDEILAGSPVTSQHVESGMRLGDVVAAALEQSDNTAGNIVLQRVGGP -AGFETALRRIGDTTTRSDRTEPDLNAAVPGDDRDTSTPRALALDLDRLVLGSVLHASERA -RLIGWMRANTTGDDLVRAAVPAGWTVADKTGTGYYGVRNDIAVVWPPSGAPIVLAIQTTK -STQAAEPSDALVAAAAKEAI--- ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Legionella hackeliae TaxID=449 RepID=A0A0A8UTF0_LEGHA ----LKKKLAELEASSGGRIGVYAINTANNAHL-QYRANERFPTGCTSKVMGVATILNQSM -NDSSLLSQKISYTKNDLTNWNPITEKHLATGMTVAELCAASISYSDNTAMNLLVKKMGGV -EQMNVFARSINDTSFRQDNWPKEALSGGKGNLKDSSTPKAMAKSLQKLAFTNVLAEPQRQ -QLLSWLKATTTGDFRIRAGVPKGWVVGDKTGTGSYGTTNDIGIIWPPKCAPIVVAVYYTS -DDKKAVKREDVVASATRLLIDKf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. 10N.261.52.A1 TaxID=1880849 RepID=A0A2N7HDS8_9VIBR ------ESIEQIESRVSARIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE -NKGLDLDSQVNIKSEDLIVWSPVTKELVDKGISLRDACSATMTMSDNTAANIVLGGIDGP -NGLTQFLRSIGDSNTRLDHLEPELNHARPDDARDTTTPKSIVMTLNKLMYGDTLSQASKS -TLKGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVALTE -TEFTLQQRDKVINEVGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas fluorescens TaxID=294 RepID=UPI00130DA964 ------------------------MDVASGAQW-SYRGDQRFPMASTFKAFTCASLLSQVD -RGRLDLSQRIAFTQDELDSYSPVTRDHVGGQLSLLQLCDAATSMSDNTATNLVLKTVGGP -AGLTAFMRSIGDNSTRIDRYEPELSDVPPGDPRDTTTPNAAAKSLQALLLGDVLSDASRQ -QLETWLVDNKVSAALLRASLPEGWKIADRTGAAEYGSRGIIAVIWPETHGPVVVAAYLSG -TRLSLEERDTVLAEVGAALV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium tusciae TaxID=75922 RepID=UPI00047F95B6 ---SVDASIQGLEQQHNALIGIFATNLVSGKTV-AHRAQDPFAMCSTFKGYASARVLQMAQ -HRELSLDDKMFVDPASILPNSPVTEPRAGGEMTLAELCQAALQQSDNAAANILLNRIGGP -QSITAFARSIGDERSRLDRWETELNAAIPGDLRDTSTPEALGGGYRALLDGDVLAPAGRR -LLEDWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGQRVVLAILTRS -QANDAENMRPLIGEITALVM--- ->[subseq from] Beta-lactamase class A n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4R8J447_9MYCO -----DADLIALEDRHGAHIGLWAVDLISGRTL-GHRADERLAMCSTFKTYAVGRVLQLAA -GGALDLDTAVPIDAADIVVDSPVTSTRIGSSMSLAELCDAALTRSDNTAGNALLRRIGGP -EAVTTFARAVGDEETRLDRWEPDLNEALPGDPRDTTTPRALNSGYRRLLVDDALDSRSRE -RLVSWMRGNVTSGKRFRAGLPAGWTSADKTGAGGFGTTNDAGLLIGPSGQRVLLAVLTRS -SARDSDPLNAAIADTVA------ ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0006A7867D --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNTILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis (strain G4 / LMG 22486) TaxID=269482 RepID=UPI000766E14B -----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Lichenibacterium ramalinae TaxID=2316527 RepID=A0A4Q2RFN3_9RHIZ ---AAEDALAALEARHGGRLGVFALDTGTGRSL-AHRADERFLMCSTTKFASVAALLARVD -AGTERRDRRVAYGAADVAVYAPDTKAHLAEGMDVEALCRAAMVHSDNGAANLVLASLGGP -DAVTRFVRGLGDGVTRFDRTEPTLNRT--DGPLDTTTPRAFAGTLRAVLLGEALAPASRS -LLEGWMVACETGRARIRAGVPAGWTVGDKTGTAGP-NAGDVALLRPPGRAPIVVAAYCDA -PKLADAEREAVLKAVGTAV---- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium triplex TaxID=47839 RepID=A0A024JWE5_9MYCO ---QVYDRLAELERQYNAYIGLFATDLGSGRAL-AHRDDDPFAMCSTFKAYAAARVLQKVQ -RGELDLQQGVFIDPAALLPNSPVTAPRAGATLPLAQLCAAAVQRSDNVAANLVLAQIGGP -PAITDFARSIGDERTRLDRWEIELNTAIPGDPRDTSTPRALGSGIQSLLTGTVLADPQRR -QLEDWMRGNVT--STMRAGLPPGWTIADKTGTGDYGSTNDVGMVYGPTGQRVLLSLMTRS -QAPDAQALRPLIAEVTKSVL--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium marinum (strain ATCC BAA-535 / M) TaxID=216594 RepID=B2HFS3_MYCMM ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Actinokineospora mzabensis TaxID=1470177 RepID=A0A317S159_9PSEU -----AEELVALESTFGGRLGVYAVDTADGTEV-RHRADERFLMCSTAKVPVSAAVLRRRL -AEPGLLERVIRYTEADLLEYAPVTSEHVAEGMAVADLCVAALTRSDNTAVNLLLPLVGGP -AGVTDFVGTLGDRTTRFDRPEPDLNVTAPGDERDTSTPLALSSTVRALVVDDGLDRPGRE -LLAGWMRASVTGKDLIRAGVPAGWDVADKSGSGAQGEVNNVAVVWPPNRAPWVITVFTSP -TDPKTTRGRTTVAAAAGIVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000B914406 ------RAVQEVEQSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLIKEEAIQSYAPTTKELIGQQVSAAQLCAITMRNSDNSAANGVLEVLGGP -EAITSFLRGVGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLRNLVLGDALKASDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERGPLVAAVYITE -TKASMEARNAAIATIGKAMA--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Methylobacterium TaxID=2615210 RepID=A0A5C8T6X4_9RHIZ ---AAAARIVAVEARLGGRVGVAFRD-ASGVFL-GHRAGEAFAMCSTFKVLAAAAILARAA -AGAETLDRRIAYAAADLQSYGPVTRAALANALTVEALCAAAIVWSDNTAANLLLDALGGP -AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPSAITGTLERCLLGDVLTPPHRA -RLEGWMVACETGRTKLRAGLPLDWTVGDKTGSGDNATSNVVAILHPPGRPPILAGLFLTG -SEAPPATRDAAHAEIGRILVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A345N7N7_VIBPH ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLVRSALPAGWFIADKSG----------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=UPI0007EA4D3A ---AVEAQIAALEIQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARTLQMAE -RGELSLEQSLFVDPEDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP -QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGFGYRNLLAGDALAPPQRS -RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIAYGPDGQRVLLALMTRS -QTADAPGLRPLIGELTSLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=UPI001065ECF4 -----DADLIALEDRHGAHIGLWAVDLISGRTL-GHRADERLAMCSTFKTYAVGRVLQLAA -GGALDLDTAVPIDAADIVVDSPVTSTRIGSSMSLAELCDAALTRSDNTAGNALLRRIGGP -EAVTTFARAVGDEETRLDRWEPDLNEALPGDPRDTTTPRALNSGYRRLLVDDALDSRSRE -RLVSWMRGNVTSGKRFRAGLPAGWTSADKTGAGGFGTTNDAGLLIGPSGQRVLLAVLTRS -SARDSDPLNAAIADTVA------ ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea candida TaxID=359159 RepID=UPI0005BA7D93 ---RVKKELRALERAFNGRIGAYAFDAASGRTV-SYRAGERFPMLSTFKAPLCAAVLHKAR -TSPGLMSKVIRWTAADMTPNSPVTEKHLKDGLTVSRLCEAAVTRSDGTASNLLLRQIGGP -AGLTAYFRTLKDPLSRMDRWHPELNDWTPKDKRDTTTPAAIARDLRLLTTGTALHAKDRE -QLLAWLLRSEVGAERIPAGLPKSWTVAHKTGTNSFGGGNDVAVIWPAKGAPIVMAVYTNR -TP-GLPTDNQTIAKTATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI0011105F7E ----LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANVLSKVD -KNKISLDDSISLKKSDIVTYSPVTEDYIGKKLTLRKACEAALTYSDNTAANYTISAGGGP -EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL -QLKKWMKGNKVANDLLRASLPQGWSIADRSGASDYGVRGIISMAWSKDHEPVIITMYVRK -SNTTMKERDQVIADIGKVIFEQy ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=Q397K2_BURL3 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGATSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRA -QLTEWMVGGARGATGIAAGVPSGWRIADKAGTGGYGTTTDIAVLWPPSRAPIVLAVSFTQ -PQAGAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=A0A2T3Y4F3_9BURK ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMAIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRE -LLKAWMLGNVTGAARIRAAVPSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKETLPRDEVVVEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae JS60 TaxID=931627 RepID=G4I8K6_MYCRH ----LEQRIAALEKRHNASVGLYAQDLDSTATV-AHRDGDRFAMCSTFKAYLAARVLQKAQ -AGELQLTDTALVDPDLLRTNSPRTEPNVGKQMALSDLCAAALQVSDNTAANVLLRVIGGP -PAITAFARSIGDDRSRLDRWETELNSALPGDPRDTSTPRALGGGIVAVLTGGVLDAPHRQ -QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDYASTNDVGIAFGPNGERLLLAIMTRT -RSANAPALRDLIAEVATLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D06D17F ---ALVDIIKQQEKALNGTIGMAVLYTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum frisingense TaxID=92645 RepID=UPI00028C1642 ----ATSPLAELEHRYGGRLGVFAVDTGSGKTL-AHRADERFLMCSTFKGMLAAQVLARVD -QGKESLQRSIPYTRKDLIFTSPTTLTNVGRGMTVGELCQATLELSDNTAAILLMRNAGGP -DGLTAFLRSLGDTVTRSDRYEPMSNQY--SGERDTTTPRAIVGNARAILTGDVLSPDARQ -QLEDWMIACRPGRNRLRAALPADWQAGDRPGTSVERQTNDYAIVRPPQRNPLFVAAYYDA -PTLDMPRREAALREVGEIFV--- ->[subseq from] Beta-lactamase n=3 Tax=Atlantibacter hermannii TaxID=565 RepID=H5V4T3_ATLHE ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTSPPLISANRA -TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANETIAEIGKQLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE482A ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEQ1_9BACT ---TLSKAVQAEEARLGARIGMAVFDAKDRTRW-AHRGDERFPLNSTHKSFSCAALLKQVD -RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP -QAFTVFMRDIGDQHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA -LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ -TSAPMADSNAAIARLGSVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. BH-1 TaxID=2058884 RepID=A0A2N6J8J9_9BURK ----ATSPLAELEQHYGGRLGVFAVDTGSGKTL-AHRADERFLMCSTFKGMLAAQVLARVD -QGKESLQRSIPYTRKDLIFTSPTTLTNVGRGMTVGELCQATVELSDNTAAILLMRNAGGP -EGLTAFLRSLGDTVTRSDRYEPMSNQY--SGERDTTTPRAIVGNARAILTGDVLSPDARQ -QLEDWMIACRPGRNRLRAALPADWQAGDRPGTSVERQTNDYAIVRPPQRNPLFVAAYYDA -PTLDMPRREAALREVGDIFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI0013F44375 ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAGARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000D00DF53 ---RAQAELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNAVGPGDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGAAAAVPPGWRVAAKRGGGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A658D4N1_9BURK ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRVDAAPRSDVIASAARIAAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9099 TaxID=2184568 RepID=UPI000F5EBE44 ----AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio bivalvicida TaxID=1276888 RepID=UPI001428D338 ---AVEKAIERQEETLSARIGVAVLNVETGALW-SFRGDERFPLTSTFKSIACAKLLYDAD -QKTTELKKTVTVNREGLVAYSPVLEAYIDKEITLGDACQATMLTSDNTAANIVIASVGGT -DSITSFVRELGDENTRLDRVEPELNEALPNDPRDTTTPISMTNTLNELVFGAVLSENSRA -QLIDWMKRNEVTGNLLRSVLPVGWEIADRSGAGGFGARSINAVVWLDKKSPIIVSIYVIQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F7ADCF ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTV----------------------------- ------------------------ ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI000312F63D --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SSKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNAILNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Beta-lactamase n=1 Tax=Legionella maceachernii TaxID=466 RepID=A0A0W0WCW3_9GAMM ---SINQKLSQLESSSGGRIGVYAINTANNTHL-GYRATERFPMACTSKVMGVAAVLKKSM -KDKSLLAQKITYTKSDLTNWAPITEKNLNTGMSVKALCAAAISYSDNTAMNLLLKQLGGV -KGMNAFARTIHDDMFQQTHWPGEAMSGGQHNSDDSSTPAAMANSLKRLAFTDVLAKPQRE -LLLTWLRANTTGNSRIRAGVPQGWLVGDKTGSGYYGTTNDIAIIWPPKCAPIVMAVYYTS -NNKEAPKRGDIVASATRIILDEf ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A4Q5PYE4_9BRAD --------LLAYERDSGGRIGLYARNITSGAEI-AWRADERFVMCSTFKASLAACMLARVD -RGEDRLDAMVAYTEKDLLDYAPVAKEHLAKNLSVGEMARAIVELSDNTCANLLLARAGGP -AALTRFWRDHGDSISRLDHDEPELNRTPPGGLDDTTTPRAMATSLQRLALGDALQPRSRA -QLIEWMVNCKTGANRLRAGLPTTWTIGDKTGNNGSDAAGDIAVVWPSADRPVVIAAYTRG -GRPTPAQLNTVFKAIGELA---- ->[subseq from] Beta-lactamase n=1 Tax=Hyphomonadaceae bacterium TaxID=2026748 RepID=A0A3D3Z4A8_9RHOB ----PTAELAALEAKSQGRLGVGILDIASGELV-GHRQDERFALCSTFKLPLAAEVLRDVD -AGKRTLDQFIPYSKADMVAHAPVTEANLAAGMAIGELAKATQITSDNPAANLILREFGGP -EAMTQRIRAAGDPVTRIDRYEPMMNRVVGDDPRDTTSPAAMARLVARYLTTDYLSQASRD -LLIGWMIETQTGTKRLRAGLPVDWKAGDKTGTAMTDRYNDVAIVWPPGRAPLIIAAYFNT -NIDMRDEFQAVLAEAGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00075AA0B2 -----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase class C n=3 Tax=Burkholderia TaxID=32008 RepID=A0A132D7S0_BURVI -----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRAAPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio bivalvicida TaxID=1276888 RepID=A0A177Y2S2_9VIBR ---AVEKAIERQEETLSARIGVAVLNVETGALW-SFRGDERFPLTSTFKSIACAKLLYDAD -QKTTELKKTVTVNREGLVAYSPVLEAYIDKEITLGDACQATMLTSDNTAANIVIASVGGT -DSITSFVRELGDENTRLDRVEPELNEALPNDPRDTTTPISMTNTLNELVFGAVLSENSRA -QLIDWMKRNEVTGNLLRSVLPVGWEIADRSGAGGFGARSINAVVWLDKKSPIIVSIYVIQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. (strain 113P3) TaxID=292913 RepID=UPI0009FA9805 -----AGRLAALEREAGGRLGVLFLDSANGRSA-GHRSDERFALCSTVKWPLAAVVLDAVD -AGGLSLDQRIRFDKSDLLSNSPRTRENLARGMSVAELLEAAITVSDNAAANLLLPLVGGP -EGVTRQFRAWGDAVTRLDRREPMLNRVGEGEVRDTTTPAAMAALLRTLLLGDALSDASRK -RLIDWGAATTTGPRRLRAGLPASWVLAHKTGTAMMNKYNDIAIAYPPRGAPLLIAAYYEG -PVAVRGEDEAVLAAVGKLAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=UPI0007226839 ----ARERFEKLEASSGGRLGVAALNTADGSYV-GYRESERFPMCSTFKLLVVALVLKRSM -AERGLLDERVRYGDADLVANSPVTKRRVGEGMTIGELSAAALQHSDNTAANLLLTAVGGP -EVLNQFALSIGDEWFDLLRGEPEVNASVPGDMRDTTTPRAMMLDVQKLLLDDVLGPQQRA -LLKAWMLGNVTGAARIRAAVSSGWLVADKTGSGDYGTANDVAVVYPPSAAPFVIAVYFTG -VMKETLPRDEVVVEAARIVFD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7Z9_9BACT ---------ENIEERLDARVGLLIRDSGTGWSW-GHRADERFLMNSTAKVPLCGAVLAQVD -KGAMRLTDGLDVRAEDMVEYAPVTELRIGDTMQVGELCFAALDMSDNAAANSLIDHLGGP -QEVTAFMRQIGDDVSRLDRREPDLNRFETGDPRDTTSPAAAVDTLERLLVGDALSPSSRA -QLTEWMTPGGVTGALLRAFTPDSWRVADKSGSGSV-TRNIVGMIAPPQGGPYFVAIYLSE -AEADFDTRNAAVVAISAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Streptomyces philanthi TaxID=371608 RepID=A0A367FCY6_9ACTN -----AAAFKKLEAEYGARLGVHALDTGSGRAV-SYHADERFAYASTHKAFTAAAVLDTYS -LKGL-DDKSLTVGKDVPVGHSPVTSAHVGEQLTLRELCEAAVRQSDNGADNLLVRDLGGP -EKLDAYLEGLGDDVTQMNRYETALTEATPGDKRDTTTPRAFAEDLRAVTVGDALHEPERA -QLDDWLDESPTGTELIRAGVPKEWSVGDKSGAARYGTRNDIAVVRPPGKAPLIVTVMSKR -KKEDADYDDKLVAEAASVVADK- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. GY16 TaxID=2653200 RepID=A0A5P8KJC7_9ACTN ----LSPRLAELEREHAARVGVFAHDTATGRTV-AYRADELFPICSVFKTLGAAVVLRDLD -RDGEYLAKRIHYTKEYVEAYCPVTSRNVEAGMTVAELCAASVSHSDNGAANLLLREVGGP -TAITRFSRSLGDRTTRLDRWEPALNSAEPWRKTDTTTPRAIGGTYARLLLGRALPDADRE -LLTGWLIANSTNVERFLAGLPADWTLADKTGGGSYGVANDVGVVWPPHRPPLVLSVLTTK -HAPEGPSDNPLVAEVAGLIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. (strain 113P3) TaxID=292913 RepID=A0A0M4CNK1_SPHS1 -----AGRLAALEREAGGRLGVLFLDSANGRSA-GHRSDERFALCSTVKWPLAAVVLDAVD -AGGLSLDQRIRFDKSDLLSNSPRTRENLARGMSVAELLEAAITVSDNAAANLLLPLVGGP -EGVTRQFRAWGDAVTRLDRREPMLNRVGEGEVRDTTTPAAMAALLRTLLLGDALSDASRK -RLIDWGAATTTGPRRLRAGLPASWVLAHKTGTAMMNKYNDIAIAYPPRGAPLLIAAYYEG -PVAVRGEDEAVLAAVGKLAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Herbaspirillum sp. VT-16-41 TaxID=1953765 RepID=A0A1V2VI74_9BURK ----ATSPLAELEHRYGGRLGVFAVDTGSGKTL-AHRADERFLMCSTFKGMLAAQVLARVD -QGKESLQRSIPYTRKDLIFTSPTTLTNVGRGMTVGELCQATVELSDNTAAILLMRNAGGP -EGLTAFLRSLGDTVTRSDRYEPMSNQY--SGARDTTTPRAIVGNARAILTGDVLSPDARQ -QLEDWMIACRPGRNRLRAALPADWQAGDRPGTSVERQTNDYAIVRPPQRNPLFVAAYYDA -PTLDMPRREAALREVGEIFV--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=A0A1H4IA45_STRMJ ----LAQRLRALETEHGARLGVFALDTATGRTV-TYRAGERFPICSVFKALAAAAVLRDLD -HGGDVLARRIRYDAALVRRYSPVTSRNLAEGMTVSELCAAAVSESDNTAGNLLLRLLNGP -TGITRFCRSLGDGTTRLDRWEPELNSAEPWRKTDTTSPAALGGTFGRLLLGDALCLEDRR -LLTDWLVANTTNGERFRKALPTDWVLADKTGGGDYGVANDVGVVWPPKRQPLLLSLLSTT -HDPAGPSDDLLVAEATRMVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura roseirufa TaxID=2094049 RepID=UPI001041342C -----GRRLRALEKARGTRIGAYAIDTGTGRFL-GYRADERFAFLSTFKAMASAAVLRKAR -RDPGLMDRVVHYTEADLVEHSPVTKEHVATGMTVAELCDAAITVSDNTAGNLVLRQIGGP -AGHTAFLRSLGDRISRADRWETDLNIWAPGERRDTTAPRVWARDLRDLAVGPALDPADRA -RLTGWLKDSETGAARIRAGLPKDWTVGDKTGTNDAGLANDVAVAWPPSGAPLVFVVLTNR -RSGG-GADDGAVARTATI----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AU33423 TaxID=2015355 RepID=UPI000B7A57BD ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPDDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPARAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Serine hydrolase n=2 Tax=Georgenia sp. Z294 TaxID=2585135 RepID=A0A5B8ASV5_9MICO -------------AAAGVTLSVAVTGLADGASL-VAGTDERVKAASIIKLPLLATLMADVD -AGDLDLAEVVTIPAGDIVGGSGTLQDRSFPLITVGELMELMVQVSDNTATNVLIDLAGGF -DAVNEYTADLGLEDLRLGRKMI--HPASPPLQENYISAAEVTELVTLLWDGGILSESSSE -YVLDLMRGQLV-DTKFGAVVP-RAHLANKTGELSD-VSHDSGVILLPGRE-LALTATSSF -TGMPREEADVFVQEAARVVYD-- ->[subseq from] Serine hydrolase n=2 Tax=Georgenia sp. Z294 TaxID=2585135 RepID=A0A5B8ASV5_9MICO ----------------GIRASVGFTDLADGGAL-LLGSPAPYNPASVIKLSLLATVMRQAE -RGMLNLDAPVTISPYMVVAGSGSLQHEQMPYTTVRELTRLMVVQSDNTATNVLLYYT-GI -PTTRELLDDLGLEVMRFNRQMFPGDR--ISDPANVLDLADTMGLLEAMYGDDLLAAGSRD -QILTWMGDQEV-DTKFGAVLD-DAPVAHKTGETGN-VTHDVGYFLVPGHE-AAVAVLTEV -TTEAQEIGNPVVQEIGLAIYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL S-384 TaxID=1463905 RepID=UPI0004C4A2DD ---RLADSLRELEREHGARLGVLAHDTGSGTTV-RYRADEAFPLCSTFKPLAVAALMRAGD -----DLSARVHYTDADVADYAPVTGR--TRVLTVAELCAAAVEFSDNTAANLLLRRLGGP -TAVTRFCRSLGDPATRLDRWEPALNSAEPDRTTDTTTPHALARTFARLTLGDALTRPHRA -RLTAWLRASTTGAHRLRAGLPPSWALADKTGTGSYGTANDLALAWPPHRPPLVLAVLSTK -PTPTAAPDEPLLARTAALLA--- ->[subseq from] Beta-lactamase n=2 Tax=Moritella marina TaxID=90736 RepID=Q9RA17_MORMI ---TLNNSISAIEQRISGRIGVAVLDTQNKQTW-AYNGDAHFPMMSTFKTLACAKMLSEST -NGNLDPSTSSLIKAEELIPWSPVTKTFVNNTITVAKACEATMLTSDNTAANIVLQYIGGP -QGVTAFLREIGDEESQLDRIEPELNEAKVGDLRDTTTPKAIVTTLNKLLLGDVLLDLDKN -QLKTWMQNNKVSDPLLRSILPQGWFIADRSGAGGNGSRGITAMLWHSERQPLIISIYLTE -TELAMAMRNEIIVEIGKLIFKEy ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacteroides immunogenum TaxID=83262 RepID=A0A179V839_9MYCO ----KSTELASLENDFGGRLGVHALDTGSGDTL-SHRANERFIMCSTVKTFIVSAILHRRL -SEPGLLDKRIQYTQADIMEWAPIASQHVAEGMTVSELCDATIRYSDNTGANLLIAELGGP -KETEKYVRSLGDNVSRMDRLEEQLN--IPDGDLDTSTPLQLATNLRRLALDEGLDAQGRE -LLTGWLKRNTTGDQSVRAGVPAGWTVGDKTGGGFKGETNDIAVIWPPGRAPIVVAVLAIP -DDPKSTKGKPTIAAATRIALKAf ->[subseq from] Beta-lactamase n=4 Tax=Vibrionaceae TaxID=641 RepID=H1A9J3_PHODD ---TLNDSLYSIEQRTLGRIGVSVLD-STDQQW-HYKGNERFPMMSTFKTLACAKMLQDSD -RDILDISTMAPVKSDELIAWSPITKNMVGSSITIENACEATMKTSDNTAANIVLKHIGGP -QGVTAFLRLIGDKVTQLDRFEPELNQAKADDLRDTTTPNAMNKTLYHILFEDVLAQNSKK -QLKEWMQGNTVSDSLLRSVLPKGWSIADRSGAGANGSRGITAAIWTDEREPLIISIYLTQ -TNLSMPERNQVINEIGKAIFEEy ->[subseq from] Beta-lactamase n=2 Tax=Lechevalieria deserti TaxID=531939 RepID=A0A316I4L2_9PSEU ------DALVELEKKYDARLGVYAAGVG---TI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MTHLDKVVTYTEADLMKSSAITKRHVQTGMKLRDLCDAAVRFSDGTAGNLLLRELGGP -AELTKYLRELGDDVTRMDRIEPAITEATPGDPRDTATPRSLGTDYQRLVLGNTLDQEKRG -FLTDLLERSVTGAKRIRAGVPQGSRVASKTGTGDYGTANDIAVVWQPSREPILIAIMSSR -STADARYDEALIAEAAAYVTK-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. N23 TaxID=1987376 RepID=A0A292YNH1_9PSEU --------VDALERRYTRRIGVHAVETRTGAAV-AHRGTERFLMCSTVKALMAAFVLHMST -TDPGLLDRRVRVTRADVLAYAPITGTHVGSGMTVAELCRAAVTVSDNTAYNLLLRQTGGP -GALTAFVRGLGDDVTRADRTETTLNT--PDGELDTTTPAAMATTLRTLATTPALTPAARD -RWLAWMRANTTGDAQIRAGVPAGWSVADKTGSGDGGTKNDVGILVPPSAAPIVLTVFTVP -EHPDDGLGEQAVAATTRAAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. YC-RL4 TaxID=1682113 RepID=A0A172UQQ9_9MYCO ---TLEERIRELEARHNAFIGLYAANLQSGLVV-DNRADEPFALCSTFKTYAAARVLRGVA -DGEFSLDQPIFVPPEGVLPNSPVTGERLGQQMTLAELSQAALQRSDNLAANLLLEAIGGP -QAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTTTPRALATGYRNLLAGEALPPAQRE -LLEGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT -QSADAEGLRPLIGEVAALVVP-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=A0A3P0X4Q7_BURCE ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWLVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Enterovibrio norvegicus TaxID=188144 RepID=UPI0004749468 -----EKVIKMQEETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD -QKRTELNNTVAVNSDDLVTYSPILEAYVEKEITLGDSCQATMLTSDNTAANIVIESVGGT -ESITSFLRDIGDVNTRLDRVEPELNEALPGDPRDTTTPISMTNTLNKLLFGTVLSQDSRV -QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGARSITAVVWRDKQSPLIVSIYVSQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL99 TaxID=2528957 RepID=UPI001081F682 ----VDDQIAELERRDNVLIGLYAANLASGRTL-THRHDEMFAICSTFKGYAAGRVLQMVG -RRQISLDNRVFVDPEAIVPNSPVTETYAGAEMTLAELCQAALQRSDNTAGNLLLKTIDGP -AGITAFARSVGDERTRLDRWEVELNSAIPGDPRDTSTPAALAIGYRAMLAGDALNPPQRR -QLEDWMRANQT--SSMRAGLPDSWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDADNLRPLIGELTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q84EY3_ATLHE ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGEHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANETIAEIGKQLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT360 TaxID=1288080 RepID=UPI0003FE654B ------AGFKKLESTYGARLGVYALDTGTGRKV-SYHADERFAYASTHKAFTAAAVLHKYS ---LNGLGKQITVGKDVPVGHSPVTSTHVGEKMTLRELCAAAVRQSDNGADNLLVRDLGGP -KKLDAYLAGLGDDVTQMNRYETALTEAAPGDPRDTTTPRAFTEDLRTVALADALDRPERS -LLGDWLRDNPFGTTLIKAGMPDRWRVGDKSGAARYGTRNDIAVVRPPGRAPLVVTVMSKR -AKEDADYDDALVAEAASVVADQ- ->[subseq from] Beta-lactamase n=1 Tax=Bradyrhizobiaceae bacterium PARB1 TaxID=2015576 RepID=A0A257KLH9_9BRAD --------LPAYERDSGGRIGLYAKNLTSGAEL-AWRAHDRFVMCSTFKASLAACVLARVD -RGQDRLDATVPYTQKDLLAYAPVAKENLSKGLSVGEMAKAIVELSDNTCANLLLARVGGP -QALTKFWRDHGDSISRLDHDEPELNRTPLGKLEDTTTPRAMATTLQRFVLGDALQAGSRA -QLTEWMVNCKTGANRLRAGLPTSWKIGDKTGNNGKDAAGDIAVVWPAPDRPVIIAAYTRG -GNPTSTQLNTVFKAIGGMV---- ->[subseq from] Class A beta-lactamase n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519IGG0_9BURK --------LVELERRSGGRLGVAMLDTGNGSLA-GHRLDERFGLCSMFKLPLAAVILSEAD -QGRLALDRRVHYVAADVHGHAPVTTKHLARGMTVAELAEAAQVTSDNPAANLLLKLIGGP -AGLTARLREFGDMTTRLDRMEPEMNHVPPGEVRDTTTPAAMARLVQKIALGDVLERPTRE -CLVGWMEKTQTGLHRLRAGLPSAWRVGDKTGTYTNGRVNDVAVCWPPGRAPLIVAATYRT -PRRGRDEDEAVLAEVGRIAA--- ->[subseq from] CARB family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=UPI00124EE2FF --sQLNEDISLLEQQTSSRIGVSVWDTQADERW-DYRGDERFPLMSTFKTLACAKMLSDMD -SGKLSKNATAKVDERSIVVWSPVMDKLAGQNTRIEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRTIGDKATRLDRIEPRLNEATPGDSRDTTTPNTVLNTLRTLVEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLVAQISQLILQKy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Mycobacterium sp. ITM-2016-00317 TaxID=2099694 RepID=A0A2S8M8V4_9MYCO ------ERLQALAQRHDAEIGVYAVDLVTQHNL-AFRADETFAVCSTIKTYIAAAVLQRTQ -TGQLSLQDTVPIEPDDIRPHSPVTEPRVGTSMTLAELCQAALQQSDNAAANGLLGVLGGP -PAVTAFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALGLGYREILTGDVLEPTVRQ -QLLDWMRANQT--SSMRAGLPAGYTSADKTGSGDYGTTNDVGVVYGPAGQQVLLSLMTKS -ASGD------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0009BE8C32 ---ALVDIIKQQEKALNGTIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRFVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSVSMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=A0A1H9JUG8_9PSEU -------ALFELEKKFDARLGVYAMS-DNGSTI-EHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTVVTYTEADLMKSSVITKLNVRTGMKLRDVCDAAVRHSDGTAGNLLLRDLGGP -AELTKYLRELGDTETRMDRVEPGITSATPGDPRDTATPRSLGTDYQRIVLGDALEPAKRD -FLTGLLERTVTGAKRIRAGVPAGSRVAGKTGTGAHGTVNDIAVVWPPGREPVLIAIMSSK -SAENAEYDEALVAEAAAYVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Lichenibacterium minor TaxID=2316528 RepID=A0A4Q2U5T4_9RHIZ ------DALADLERRSGGRLGAFALDTGSGRSL-AHRADERFLMCSTTKLASVAAVLARVD -AGSERLDRRVPYTAAGIAVYAPDTKAHLADGMSLEALCRAAIVHSDNGAANLLFESLGGP -DAVTRFARGLGDPASRFDRIEPALNR--PDGERDTTTPRAFATLTRALLLGDALSPASRA -LLDGWTIDCETGGKRIRAGVPKGWTVGDKTGTAGP-VADDVALLRPPNRAPIVVAAYCDA -PGLDDDAREAVLREVGAIAAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0013659AE2 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDADADDALISGAARAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=UPI000D52CADA ------RAVQEVEQSLQARVGLAVLDTADGQWW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLIKEEAIQSYAPTTKELIGQQVSAAQLCAITMRNSDNSAANGVLEILGGP -EAITSFLRGVGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLRNLVLGDALKASDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPERGPLVAAVYITE -TKASMEARNAAIATIGKAMA--- ->[subseq from] class A beta-lactamase n=1 Tax=Marinobacter sp. JSM 1782161 TaxID=2685906 RepID=UPI0014025EDB ---RLSDTVEKVENQLDARVGLSLVDTGSDFSW-AHRADERFLMNSTIKVLICGAVLARVD -EGAMALADPLPVRQDDILSYAPVTKEQVGQDMTLGELCYAALDMSDNTAANLLLEHLGGP -ASVTRFLRRIGDSVSRSDRYEPALNTGAPGDPQDTTRPVAMSGTLSKLLLGEALTADSRD -QLVAWMSHGGVTGALLRDDAPASWHIADKSGSGDT-TRNIVALITPDDGAPRIVTLYISD -ADADFRTRNAALKELGAAVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000841BE5C -----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRT -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL7 TaxID=2603900 RepID=A0A5C8VED1_9RHIZ ---EAEPALAEIERRLGGRLGVSAG-TQERVLL-SHRADELFPMCSTFKALAVAAILARVD -AGSESLDRAVGFGPGILLSYAPVTRKVVEAGMTIADLCAAAIVWSDNSAANLLLTALGGP -EALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTTPEAMRQTLGRVLLGPVLSAASRG -QLEAWMVGCQTGAKRLRGGLPPDWIVGDKTGSGDNGTFNDVAILRPPGRAPVLACVYVTG -ATAPAAAVEAAYAEIGRLMA--- ->[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium sp. MF47 TaxID=2662028 RepID=A0A5Q2MJI1_9ACTN ---DVRDGFAALETSYDTRLGVFAVDTGTGRRV-TWRGTERFPFASTIKAPLAAVVLDRTS ---RRGLARTIHYDASDLLPGSPVTEKHLADGLPLRDLIDAALRFSDNTAANLLFEQIGGP -AQLDRELDRIGDRVTNPERTEPDLNSAVPGDVRDTTTPQALATTVGEYVVGKALPRHDRD -LLRTTMVDNTTGDALIRAGVPKEWVVADRTGGASHGVRTAVAVAFPPGRSPVLIAVMSRR -DQVGDEYDDAVIAEATRIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=A0A1X0D7T4_9MYCO ---TVEAQIAALEVQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAARTLQMAE -RGELSLEQSLFVDPEDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP -QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGFGYRNLLAGDALAPPERS -RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIAYGPDGQRVLLALMTRS -QTADAPGLRPLIGELTSLV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Marinobacter excellens HL-55 TaxID=1305731 RepID=A0A0P8BJ49_9ALTE -------------------------------------------MSSTFKTLACAALLHRVD -AGQANPARKVNVSESDLVTYSPITEKHAGGEMTLSDLCEATLATSDNTAANLVLRELGGP -EAVTTFARHLGDDVTRLDRWETELNEALPGDNRDTTTPNAMVQNLQALLLGDVLSEQSKD -QLRSWLENNQVADGLFRAAVPEGWVVADRTGAGGFGSRSITAVIWPPERQPIVVALYLTQ -TDASFEEQNAAIAEIAEAIV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium lehmannii TaxID=2048550 RepID=A0A124EQB4_9MYCO ----IEDRLGEMERRQNALIGVFATNLGTGHTI-AHRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEPGDIVPNSPVTEARVGQTMTWAELCQAALQRSDNAAGNWLLRVIGGP -SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAIGTGYRAILTGNVLADPQRR -QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAFGPAGERLLLAIMTRT -AAPDIPNDRQLVGEVASVLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000D3AABD3 ------ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAAIMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDSETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTMQERDTVINEIGQLIFDAy ->[subseq from] Class A beta-lactamase n=1 Tax=Advenella kashmirensis TaxID=310575 RepID=A0A356LME7_9BURK ---KTAALLTALERHYGGRLGVAIHDTANGTRV-AHRSDERFLICSTFKLLLTAAVLKRVD -NGKELLEQRITFDKSAIVQWAPVAGLNVGQPMSVLELCEATMIMSDNTAANLLLDTLGGP -AALTAYARNLGDTKTRLDHIEP-LNG-IQQGDEDTTTPESMLENMKKILLGGALSSESRA -RLVRMFEMNQTGSQALKAGLPANWRIGDKTGAASD-TSNDIAIITPPHREPLLVAAYYTN -DKVNSTVHKAVLAKVGEIVAK-- ->[subseq from] Class A beta-lactamase n=2 Tax=Streptomyces sp. GKU 895 TaxID=1662404 RepID=A0A1V4E6Y6_9ACTN ----APEGLRELEAQHGARLGVFARNIATGRTV-RYRAGELFPMCSLFKTLASAAVLRDLD -RDGEFLSRRIHYTDADLPKGSDKTREHLADGMTVAELAEVAITFSDNGAGNLLLRELGSP -TALTRFARSLGDRVTRLDRWETELNSAEPWRITDTTSPYAIGRTYGRLVLGDALDGRDRA -LLTHWLRGNTTSGTRLRAGLPRTWTVADKTGGGSYGTNNNVGIAWTEDGTPLLLAVLSTL -PEQDAVRDDVLIRDTAALL---- ->[subseq from] class A beta-lactamase n=2 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI001262578C ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKHDPRDTTTPNAINHTLNTLVLGETLSSASRQ -QLKTWMQDNKVADGLLRSVLLQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEASFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GS05_9SPHN -----IREVKALEMRGVGRIGVVAIDTGTGAVV-AYRADERFPMCSTHKILVGAAILSMIS -AGRLKADQRIAYGHADLLEYAPLTTKNVEAGMTVEALGEAAVRWSDNTADNLLLTLLGGP -KGWTQFARSMGDRVSRLDRFEPDLNSGTPGDVRDTSSPRAMTGMLAALLLGRALDAGPRS -KLESWMYESPITGALFRKRLPAGWHVSDKSGSGSNGTRNDVGIIYPPRSAPIILTVFHTG -SNGSTTERDEIIAECASVVAQHf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides alkalitolerans TaxID=281714 RepID=UPI0004299932 ---ATTAAFTALETAYDARLGVVAVELATGETV-AHRGDERFAFASTIKALQAGAVLRDAS ---DADLDRVVTYTEADLLEYAPITEQHVADGMTVRALLDASVRYSDNTAANLLFDEVGGP -AGLAEELALVDDTTTLPVREEPDLNTAVPGDERDTSTPAALAASLASYTTGCLLPEERRA -ELVDLLERNTTGDALVRAGAPEGWTIGDKTGSASYGTRNDIAIAWPPDRSPVAIAVLTSQ -DEQDDPTLDALVADATREAF--- ->[subseq from] class A beta-lactamase n=1 Tax=Aestuariispira insulae TaxID=1461337 RepID=UPI000E27C4ED -------ALPDIENRLKARLGAYILDTETNRVW-QHRARERFPLNSTFKAFACAGILAKTD -RGEDILDTEISFGKADLVTYSPVTEGFAGVAMPLSSICQAAMHMSDNTAANLVLDQLGGP -EGFNGFMQEIGDHTTRLDRWEPELNEAAPGDPRDTTSPEAAANSLMALALGDRLSPASRA -QLNRWLEGNQVSGPLFRSSLPKDWLIGDRSGAGGHGSRSIIAVLRPPKRKPVIAAVYITD -TSASFELRNNAIAVIGEKLM--- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus dokdonensis TaxID=302167 RepID=A0A3E0WML7_9BACI -----ESEFRLLEKAYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT ---LKQLKETVLIKEKDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP -NGFKKALRDIEDDVTNPKRMEPELNLVNPGEIKDTSTPKALATSLKAFTMGNVLPKEKQD -LLVDWLKRNTTGDHLIRAGSPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK -EEKNAEADDKLIAEATKKVI--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A5Q5CF05_MYCSJ --------LDALERANNAVVGVFAVNLDTGRTV-AHRAQESFAMCSTFKAYLAAHVLQLVG -RGERSLEQGLYVDAADILPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRDVGGP -PAVTAFARGIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALGGGFRTLLTGDVLAPPQRR -LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTRS -ATPDAENMRPLIGEVTAAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia cepacia TaxID=292 RepID=UPI00075E10DA ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPIEMIDTLQRLLLGNTLPDPQRG -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=A0A4U1ZKL9_9VIBR -------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE -TELTIPERDTVINEIGELVFDEy ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCZ2_9BACT ---TLSKAVQAEEARLGARIGMAVFDAKDRTRW-AHRGDERFPLNSTHKSFSCAALLKQVD -RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP -QAFTVFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA -LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ -TSAPMADSNAAIARLGSVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium PA3 TaxID=2015571 RepID=A0A257JTJ8_9PROT -----AEELQALEARSQGRLGVGILDTATGELV-GHRQDERFAMCSTFKLPLAAEVLRDVD -AGKRKLDQFIAYSKADMVSHAPVTGANLAAGMTIGDLAKATQITSDNPAANLIIRELGGP -TEVTQRFRSAGDPVTRIDRYEPMMNFVVGDDPRDTTSPAAMAGLIARYLTTDYLSKASKD -LLIGWMVETQTGAKRIRAGLPGEWKAGDKTGTGMADKYNDVAIFWPTGRAPIIVAAYYET -AIDTRDEFQAVLAEAGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio ostreicida TaxID=526588 RepID=UPI000970C5DB -----------VSTSLGARVGVFVNNTNTNQQW-GYNGDQRFPTASTFKVLACAAALDKGA ------LSKTVMITEKDLVEYSPVTGKHLNKTLTYEQLCHATITTSDNTAGNLVLKYVGGP -EGLTQFLRGTGDSVTLMSRWEPELNQGTPGDKRDTTTPAAINRTLDALLFGDVLSKPKQQ -QLLQWMKQDQVADDLLRSVLPKTWQIGDKTGAGGHGSRGIIAVLIPPKSKPVLVSIYITE -SQTTIKQLNKAIATIGSAIIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. djl-10 TaxID=1879023 RepID=UPI000811B40E -----AERLAELERRHNAMVGLYAVDLQTGRTL-VHRENERFAVCSTFKAYLAARTLQAAG -RGEFAMTDTVTVRAEDLLPNSPVTETRVGQTITLAELCAAVLQVSDNAGANYLLHQIGGP -PAITEFARSIGDQETRLDRWETELNSAVPGDPRDTSTPTALGNGFRALITGDALEPQART -QLVDWMLANTT--SSLRPGLPADWTFADKTGSGDYGTTNDIGVAFGPDGRAVLLSVMLRS -ASPDTEGFRPVMPEIATLVLQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_003 TaxID=2175667 RepID=UPI000DAACE78 -----APAFDRLQQTYGATLGVFALDTGTRQTV-AYNANRRFAYASTYKALAAGVLLADPS ----TDLDAHVDLAQDEILAGSPVTSQHVESGMRLGDVVAAALEQSDNTAGNIVLQRVGGP -AGFETALRRIGDTTTRSDRTEPDLNAAVPGDDRDTSTPRALALDLDRLVLGSVLHASERA -RLTVWMRANTTGDDLVRAAVPAGWTVADKTGTGYYGVRNDIAVVWPPSGAPIVLAIQTTK -STQAAEPSDALVAAAAKEAI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium riyadhense TaxID=486698 RepID=A0A1X2CSR3_9MYCO ---DIAARFSELERNYEARLGVYVPA----AQI-AYRADERFAFCSTFKAPLVAAVLHQFP ---LPHLDKVITYTSDDIRSTSPVTQQHVATGMTIGQLCDAAIRYSDGTAANLLLADIGGT -ATFTGYLRELGDTVSRLDQVEPELNRDAPDDQRDTTTPHAIALVFQQLVLGNALPADKKA -MLIDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDVAVVWSPTGVANVVAIYSDR -AAYDAEPSDGLIAEAAALVA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Klebsiella TaxID=570 RepID=A0A1G5SA95_KLEPN ----------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis halotolerans TaxID=124252 RepID=UPI000A3142B7 -----DSAFARLEGEFGVRLGVYALDTGTGQAV-EFQSDERFAYCSTFKALAFGAVLDRTP ---IDELDRTVTFSEADLVFHSPVTREHVATGMTLREIGDAALRHSDNTASNLLLQELGGP -EELERALRGIGDEVTRVDRVAPEMAEAVPGDVRDTSTPRAMATSLREFALGDVLSEDKRD -ILTGMMRANTTGDDLIRAGVPEDWTVGDKTGACGYGTRHDIGVLWPPEGAPV-------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI000247844E ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNALLFGNTLNPQDKQ -TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000F67A616 ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDAFKTSDRD -RLTDWLRHNEVGGPLLRAGVPESWNVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Aestuariispira insulae TaxID=1461337 RepID=A0A3D9HMY0_9PROT -------ALPDIENRLKARLGAYILDTETNRVW-QHRARERFPLNSTFKAFACAGILAKTD -RGEDILDTEISFGKADLVTYSPVTEGFAGVAMPLSSICQAAMHMSDNTAANLVLDQLGGP -EGFNGFMQEIGDHTTRLDRWEPELNEAAPGDPRDTTSPEAAANSLMALALGDRLSPASRA -QLNRWLEGNQVSGPLFRSSLPKDWLIGDRSGAGGHGSRSIIAVLRPPKRKPVIAAVYITD -TSASFELRNNAIAVIGEKLM--- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00052D8055 -----AQAAQVVEQSLQARVGLAVLDTTDGQLW-QYRADERFPMASTSKALICAALLARGP ----GAMKTAWLVKEEAIQSYAPTTENLIGQYVPASQLCAITMRNSDNTAANGVLEMLSGP -EAITSFLRSVGDTVTRLDRNEPSLNEATPGDPRDTTTPQAMVHTLQNLVLGDALKAPDRD -RLIDWLRHNEVGGPLLRAGVPESWTVADRTGAAAYGTRGVVAVMWPPGRAPLVAAVYITE -TKASMEERNAAIATIGKAIA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9H1_SHIFL -----------------------ELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELSSPAINMSGNTAANLLLTTTRGP -KELTAFLHNMGDHVTRLNRGEPELNEAIPNDEHDTTVPAAMATTLRKLLTGELLTLTSQQ -QLIDWMEAVKVAEPLLRSALPAGWFIADKSGAGERGSRGIIASLGPDGKPSRIVVIYTTG -SQAIMDESNRHIAEIGASLI--- ->[subseq from] Uncharacterized protein n=1 Tax=Nocardioides luteus TaxID=1844 RepID=A0A1J4N769_9ACTN -------SIDALEQKHQRHLGVWAQNVRTGRVV-EHRADERFPMLSTFKTLLVSAILRDLP ---ARTLQQRLTWDDADVVVNSPVTSLTTRNGLTVAQLAEATMTRSDNTAANELLQLIGGP -AGVTSLARSLGDTVSRLDRWEPDLNSAIPGDPRDTTSPRAIARTYTKLVLGDALGGADRD -QLLTWMLANQSTVSRFGAGVPAGWRLADKTGGGDYASRNDVGVTWTPDGAPIVIAALTRS -DDPAAPPLDAPLADIAATVCA-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI0009899530 -------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDERNTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE -TELTIPERDTVINEIGELVFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. 624788 TaxID=1234362 RepID=UPI000474F6E2 -----AQSIAQIESRVSARIGVAVYDSATEQTW-SYKSDERFPMMSTFKTLACANLLYVHE -HEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLRDACASTMEMSDNTAANIVLASTGGP -NGLTEFLRSTGDSKTRIDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMGNKVSDGMIRSILPDGWKIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTISERDTVINEIGELIFDEy ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. CUA-806 TaxID=1517936 RepID=A0A1Q9U3C4_9NOCA ---AIEDDMTALEQRYGARIGVWASDLTSAATA-SHRPHESFAMCSTFKPYAVAAALQLAS -RGRLNLDEVVPVTAADIVVNSPVVSNLIGGSITLSQACDAALTQSDNTAGNILLRAIGGP -PAIAAFARSVGDPRTQLDRWEPELNEALPGDLRDTTTPEALAAGYRAILIGDMLEKSHRD -RLVGWMRATRTSDKRFRAGLPQGWSSADKTGAGDYGSTNDAGLLLGPSGQEILVVVMTRS -RDKDAPPFNDAIADTVRLTLSKf ->[subseq from] class A beta-lactamase n=1 Tax=Roseomonas aerilata TaxID=452982 RepID=UPI0012EC9C05 ------AALREAERAGGGRLGVAVLDTATRAWA-TWRGAERFPLASTFKLVLAGAVLREVD -EGREDLERRVPIEASDLVDYAPVTEKRVGPEMRVGELLEAVMVWSDNAAANLLLPLVGGP -EGLTERAGDWGDAGFRLDRRETALGEGRPGDPRDTTTPNFMLVSMERLLVGNLLSAPLRG -LLNAWMIGCRTGDTKIRAGLPQGWICGNRSGAAGFGTSNDVAAIWPPGGRPILVAAYLTE -SAAPLQARDAALAAVGRAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI00142F817E ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDADADDALISGAARAAAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9131 TaxID=2184571 RepID=A0A3N8AQT1_9BURK ----AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852014-52144_SCH5372336 TaxID=1834115 RepID=A0A1A0USS0_9MYCO ----IEDRLGEMERRQNALIGVFATNLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRITIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAGNWLLRVIGGP -SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAIGNGYRAILTGNALAEPQRR -HLEDWMRANQT--SSVRPVLPPGWATADKTGSGDFASTNDVGIAFGPAGERLLLAIMTRT -AAPDVPNDRQLVGEVASVLV--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=A0A2N7K9D4_9VIBR ------ESIEQIESRVSARIGVSVYDSATKKTW-SYKGDERFPMMSTFKTLACANLLYDSE -NEGLDLESKVGVKSDELIAWSPMTKAFVGKEISLTGACSATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDVRDTTTPNTMVKTLNELVYGNVLSEASKA -QLKTWMKDNKVSDGMIRSILPDGWKIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TKLTIPERDTVINEIGELIFDDy ->[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A2U2BNW9_ALCFA ------QAAQEAEQSLQARIGLAVLDTADGQLW-LYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAVQSYAPTTENLIGQYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKISDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI000D0809B6 ---ALVDIIKQQEKALNGIIGMAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKSVLTHSVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRLVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] class A beta-lactamase n=1 Tax=Aquidulcibacter paucihalophilus TaxID=1978549 RepID=UPI000A1907CA ----PTAELAALEASSQGRLGVALLDTATSELV-GHRQDERFALCSTFKLPLAAEVLRDVD -AGTRKLDQFIPYSAADMVAHAPVTGANLSAGMTIGDLAKAAQITSDNPAANLMMAELGGP -EGMTQRFRAAGDAVTRLDRYEPMMNHVTAGDPRDTTSPAAMVRLIARYLTTDYLSQASKD -LLVGWMIETQTGLKRIRAGLPAAWKAGDKTGTAMTDKYNDVAIVWPPGRAPILIAAYFNT -LIETRDEFQAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852013-51886_SCH5428379 TaxID=1834111 RepID=A0A1A0TBZ2_9MYCO ------DRIGALERRYDAVIGVYAVDLASGRTV-AHRAQETFALCSTFKGYLAALVLRMVG -RGERSLEQRLYVDPAAILPNSPRTEPRAGGDMSIDELCQAILQVSDNAAANILLHNVGGP -AAVTEFARSIGDPRSRLDRFEIELNSAVPGDPRDTSTPEAVGNGYRALLAGDALMPAQRQ -LLEDWMRANET--SSMRAGLPPGWTSADKTGSGDYGTTNDVGIAYGPQGQRVLLAVMTRS -AAAEAENNRPMIGEVASVVMQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Colwellia piezophila TaxID=211668 RepID=UPI0003AAD9A4 ----ITKKIEEIENKLGARIGASIYDVTDNKFW-SYKGDTRFPLLSTFKTLACAKLLADVE -KGLQSFETSSVITTSSLVKWSPVTKNHVGEKFSLKQACSAAMIMSDNTATNIVLTGIKGP -KALTHFMRSIGDDVTRLDRIEPYLNEALDGDKRDTTTPNAMVKSLHTLLFGDALSQASKA -QLKQWMIDNKVTGSLLRSVLPENWSIADRSGAGGNGSRAITAVIWSDKRSPLIISIYLTQ -TDASFALRNKAIADIGKEMFTVy ->[subseq from] class A beta-lactamase n=1 Tax=Phaeobacter gallaeciensis TaxID=60890 RepID=UPI000BBCDA18 ---DLAETIRSWETALDARLGVLLIHPATGWEI-AHSADDRFPLNSTFKPLLCAAILSQVD -QGTEDLTARVEIRRGDLVSHSPVIERYIGTTRSLAQLCEATITRSDNTAANLLLERIGGP -EGFTEFMQISGDLITRLDRWETGLNSATPGDHRDSTTPRSVLSTLYLALSGTILSGPSSA -QLTDWMQRDQLADDLIRAHLPEGWTIGDKTGAGGHGSRGIIAFLRDPQGSEYLAAIYITE -TDANFARRNQAISDIGRAMI--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium palauense TaxID=2034511 RepID=UPI000BFEE842 ----VDERLRTVERLHNASIGVYAVDLDSGRNY-ASLADERFALCSTFKTYAAARVLQMAA -GGELHLQDEVFVDPTAVVDYSPVTAPLAGVQITLETACRAALQHSDNTAGNLLLARIGGP -PAVTAFARSIGDQQTRLDRWETDLNTAAPGDPRDTSTPRALGEGYRALLVGDALDEASRG -TLVTWMRGNVTSVHSMRAGLPADWTTADKTGAGGYGSTNDVGVVFRPGGGRLLLSVMCRS -RTDDAESSQRMIAQVTAAML--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4W207_9ACTN -----RKELRKLEVAFKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLQKAR -TSRGLMSRLIKWTAADMKPNSPVTEKHVKDGLTVSQLCEAAVTMSDGTASNLLLKQIGGP -KGLTKYFRTLKDSTSRMDRWHPELNDWTPREKRDTTTPAAIGRDLRVLTLGRALHAKDRR -QLLAWLLANKTGGERIRAGLPGTWTVADKTGTNSFGGGNDIAVVWPGKGAPLIMSIYTNR -TK-GLPTDNKTIAKTATVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=A0A2T0R071_9ACTN ---AVQARFAQLEESFDARLGVFAVDTGSGRTV-VHRGDERFGFASTYKALAAGALLERTG ---DAELDAVVTWTADEVVAHSPVTGQHTASGLPLRQVAEAAVTVSDNTAANVVLAHLGGP -AGLEEDLRALGDDTTEVEHTEPDVNDITPGDPADTSTPRAMATTLQAYATGDVLAPAGRD -QLVRWLQAGTTGGGQIRAGVPAGWVVGDKTGHAGYGNQNDIGVVWPTGGAPWVLAILTDR -ADVDATSDEALLARATEVVVDE- ->[subseq from] Beta-lactamase n=8 Tax=Bacteria TaxID=2 RepID=A1E3K9_ECOLX ---SIDDTVKQVETTLGAKVGIAVLDTGSQRAW-FHRADDRFPMASTSKALTCAALLDK-- --GQSFMNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGP -QAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLGSDERK -QLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGNGTRGVIAVMWPPKHAPIIAAIYITQ -TKATMEERNAAIASIGKAIAA-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacteraceae bacterium TaxID=2052182 RepID=A0A522RLC4_9GAMM -----GARLSALEQQHGGRLGVAILDTGSGLRA-AHRGGERFLMCSTFKLLLAAAVLTRVE -HGEEKLDRRIVFNESVVLDYAPITKQRVGPPMTIAELCEAAITLSDNTAANLLLEAIGGP -AAVTQYARTLGDTFTLLDRTEPSLNPY------DTTTPLAMLGDMQEVLLGDALLQTSRK -RLTHWLLDCQTGLQSLRAGLPSGWGIGDKTGQWDAGANNDIAIIWPPGRKPLLVTAYYMN -HTTDPVGRKAVLAEVGRIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio sp. V24_P1S3T111 TaxID=1938676 RepID=A0A6B2BNK6_9VIBR ---QLTQAVKDIESDWQGRIGVYAYDINGSFTF-GYREQERFPLCSSFKSLLAAAILQKSQ -NQLLNLETFIDFSKRELEFWSPITEKNHATGMSIGELAQAALQYSDNGATNILLERIGGP -QGMNNFMKSIADQDFRLDRWELELNTAIPGDERDTSTPRSMATSLGKLSFSNVLTASHQN -LFHDWLIGNTTGDNRIRAVVPKQWKVGDKTGTCGYGAASDVAVIWREKASPLVIAIYTHK -SEPTAKHSDKLIAEVAKETLQ-- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella sp. VKM Ac-2527 TaxID=2512215 RepID=A0A4R6JNK4_9ACTN ---DLKGRLQDLERDKDCRIGAYALDVGNGRTV-RYRGDERFPVLSTFKAFLGAAMLDRSR -YEPGLLRKRLTWAKADLVANSPITSQHIDDGLTVAELCWAAICVSDNTAANVLLKQIGGP -DGLTCFIRRLGDPVTRLDRWEIELNNWSPSERRDTTTPTAAGRSLRMLTVGGGLHPADRT -ALIAWMRAARTGGKRIRAGLPKTWIVGDKTGTSSYGSANDIAIAHPRSGAPLILAIYTNR -SQPTQVTDEAIIASTATALAQ-- ->[subseq from] Beta-lactamase n=3 Tax=Mycobacterium TaxID=1763 RepID=A0PQQ2_MYCUA ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYS ---IAHLGTVITYNSADIRSTSPIIEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A2S9M1E4_9BURK ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000D3C4404 ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWIETRAPLIISISLTE -TELTMQERDTVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=2 Tax=Actinomadura umbrina TaxID=111806 RepID=A0A3D9SPP0_9ACTN ---EVTKRLRALETAYRGRIGAFALDTGTGRVV-GHRAQERFPFLSTFKALAAGAVLSRAH -RDPGLMDRVVHWTSEEVKPNSPITEKHTGPDLTVARLCDAAIRYSDNTAGNMLLKQLGGP -AGLTGFLRSLGDPVSRLDRWEIELNDWSPGERRDTTTPARAGTDLHRLTAGGSLVPQDRA -RLVGWLRGNTTGDTRIRAGLP-NWTVGDKTGSNG-GMANDIAIAWPPGSAPVILAVYTHR -LDPTAPREDEVVADAAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBD17_040 TaxID=2175674 RepID=A0A2W1Z7T1_9MICO -----APAFDRLQQTYGATLGVFALDTGTRQTV-AHNANRRFAYASTYKSLAAGVLLADPS ----TDLDAHVDLAQDEILAGSPVASQHVESGMRLGDVVAAALEQSDNTAGNIVLQRVGGP -AGFETALRRIGDTTTRSDRTEPDLNAAVPGDDRDTSTPRALALDLDRLVLGSVLHASERA -RLIGWMRANTTGDDLVRAAVPAGWTVADKTGTGYYGVRNDIAVVWPPSGAPIVLAIQTTK -STQAAEPSDALVAAAAKEAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia TaxID=32008 RepID=UPI00064E626F ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPVTESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARASGDTSFRLDHWEPELNHAAPGDERDTSTPVEMIDTLQRLLLGNTLPDPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVVSAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella sp. J329 TaxID=1977852 RepID=UPI000FDA0DDC ---TLSKAVQAEEARLGARIGMAVFDAKDRTHW-AHRGDERFPLNSTHKSFSCAALLKQVD -RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP -QAFTVFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA -LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ -TSAPMADSNAAIARLGSVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea phyllanthi TaxID=2219224 RepID=A0A5C4W7D6_9ACTN ---QARKELRALEKKFGGRIGAYAIDTATGKTI-AYRSAERFPLLSTFKAMACAAVLHKAR -TEPGLMDKVVHWTAGEVKPNSPTTSKHVKDGLTVSRLCEAAITLSDNTAGNMVLKQIGGP -AGLTRYFRTLKDPLSRLDRWETELNDWTPKDRRDTTTPAAIARDLRAVTVGSALDARDRR -RLNAWLRATETGDARIRAGLPKGWTVGDKTGSNSFGGGNDIAVVWPGKGAPIVMAVYTHR -AA-GQAGDDTAIARTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=A0A1G7R930_9PSEU -----TGRLRELERRHGARLGVFALDTGSGRTV-LHRADELFPMCSTFKTLAAAAVLRRDV --DGSLLGKVITYTQAEADKYAPITGANLANGMTVSALCEATITYSDNCAANLLLRELGGP -TAISRFARSIGDPVTRLDRYEPELNSAEPGRRTDTTSPRAIGQSYARLTLGHALDRPDAE -QLTNWLLANTTGGNRVRAGLPAEWGWGDKTGGGSYGTTNDVGIAFPPGRAPIVIATLSTR -ESPDGGADEPLLVKTAQLLAETf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. URHA0002 TaxID=1298867 RepID=UPI0004877F40 --------LLAYERDTGGRIGVHAENISTGAKI-AWRAEERFVMCSTFKASLAAFVLARVD -NASDRLDEMVAYGPKDLLDYAPVAKQNLAQGMSVSDMCKAIVELSDNTCANLLLARVGGP -AALTEFWRRAGDTVSRLDHNEPELNRSPPGDIHDTTTPSAMAGNLRRFVLGTVLTPSSRE -QLTLWMVDCKTGNNRLRGGLPADWKVGDKTGNNSKDASGDIAIAWPKSGGAVLVAAYTQG -GSPTRQQLEAVFKEIGAMV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAV6_KLEPN ---------AELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bombella sp. KACC 21507 TaxID=2697033 RepID=UPI0013668ECA ---SLEPDFAAIERRSGGKIGVSVLDTETGKTL-QWRANDRFPFCSSAKVPLVAYVLWKAD -RGEISLDQIVHYTEADLLPYAPVTRVAVSKGLSIAELCQAAVTLSDNTAANLLWRETGGY -KALNAWMQSEGDHEFNLSGIEPELNWAQYGDRHNTTTPVAMAKTYERFVLGDTLKSASRD -KLTNWLLSNKTGERRIRAGLPHAWRVGDKTGTFNYFSTVDIGVVWPIARRPMVIACFVAG -TP-DTDSAEYAIAEAAQAIA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6B9_9BACT ----VLTEIKRVERELDARVGVSIYDVKTKKLW-SYNGEARFPLLSTFKTLACAKLLVDSD -KGNISIYTSVEVHSESLMEYSPVLEKYVGKKITLGEACSATMQMSDNTAANIILTSIGGP -QELTKFMLGIGDSVTRLDRIEPSLNEALATDVRDTTSPNAMTKTLNTLLFGTVLSTESKA -KLKQWMVENKVSGSLFRSELPSGWYIADRSGAGGNGSRAITAIIWSNERSPLIVSVYLTQ -TEASFENRNKAIAKIGKEIFKQy ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A4R7QGV4_9BURK -----TNPINNIERRHGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLTRVD -AGKENLDRLVHYTEKDLIFTSPVTKANVAQGMSVRAMCQAIVEVSDNTAATLLMRDAGGP -PALTQFVRSLGDTVTRSDRYEPDSNQY--SGARDTTTPKAITKSVGKILLGNVLSAQSRQ -QLESWMIDCEPGLDRIRAALPTDWVAADRPGTSVEEETNDYAIVRPPGRAPLLVAAYYDA -PYVDMDGREAVLREVGAAFVD-- ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter malorum TaxID=178901 RepID=A0A177GA41_9PROT ----VASVLSEYEDATGGRIGVYARNLVTGQSL-TWRENERFAVCSTFKASLVALVLLRVE -QGHERLEDMVPYTQADVEKYAPVAQAHVEDGLTVRTLCQAALEQSDNACANLLLARVGGP -AMLTRFWRSLGDTKTRLDDWEPVLNRTPPGGLRNTTTPRAMAGTLEHVLFGDTLSVSSRT -LLTDWLKGCRTGTHRLRAGLPEGWGVGDKTGNNGRDAVSDIAVAWPAPQRPIILSVYTRG -GHPVEEQFRTAFAGIGRMV---- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) TaxID=482957 RepID=A0A3G3HB92_BURL3 ---AAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDASFRLDHWEPELNNAAPGDERDTSTPVGMVDTLQRLLLGNTLLEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Agrobacterium sp. SCN 61-19 TaxID=1660088 RepID=A0A1E3YGY0_9RHIZ ------AAAQRMEQKLGMRVGLSVIDTGRGTVV-AYRETERFAMASTFKSLACAAALSGGD ----AVLEQTTRITKADLRPHSPVTEKRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP -AEVTSFLRGIGDTTTRLDRYEPEVNEATPGDPRDATTPQAMAQTLERLLVGAALAPADRD -QLDAWMSANAVADGLLRSRLPKGWQIADRSGAGGHGTRGVIAVVRPPGAQPLVIAIYMDG -KTHPLKTRDAAIAEIGATIFAGy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00068D0026 ----LARRFRALEEEYAARLGVYAYDTATGRSV-RYRADETFALCSVFKTLAAGAVLRDLD -RNGEFLAKRIRYTEQQVTDYAPVTGRNLADGMTVEALCAAAVSESDNCAGNLLLSELGGP -TGITRFCRSLGDRTTRLDRWEPDLNSAEPWRTTDITTPHAIGRTYARLLLGRALPDADRE -RLTGWLIANTTNGERFGTGLPDDWTLADKTGGGSYGVANDVGVAWPPGRPPLLLAVLSTK -KDPAGPTENALVARAAAQVA--- ->[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium gilvum TaxID=1804 RepID=E6TFK0_MYCSR -----EERIAALAARHDARIGLYAADLDSGATL-AFGDTDTFAVCSTFKTYAAGAVLQRVQ -QGRLGLGDTVLIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSDNAAANGLLRVLGGP -SAITEFARSIGDDRTRLDRWEVELNSAVPGDPRDTSTPRALATGYQALLTGDVLDPIGRR -QLVDWMLANQT--SSMRAGLPAGYTSADKTGSGDYGSTNDVGIAFGPAGQRLLLAVMTRS -ASPDAPSLRPLIGELATLVL--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0IN24_9SPHN ---------KDIEQETGGRLGVALVDKEGALIL-GFNRDDRFAMCSTFKAPLAAAVLMGAD -AGKFGLEGQIPFTKNDILDYAPVVKQNRKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -QGLTAFFRAYGDKVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMARLLFRDM-KPESAE -RLRGWLNANTTGDKRIKAGLPEGWTSGSKTGTCGN-AYNDVALVKSPKGDEYILAVYLDR -PTVDQKASEAAIAEAARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFFB6B1 ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVITAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESQADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0009082A20 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -ALKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus Rock3-29 TaxID=526984 RepID=C2V7Y8_BACCE -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLIKNS ---LEALDQKIRYTHEDLSNYNPITEKHVDTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKNQLFLLYF--- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI0011B6E415 -------SIAKIESRISARIGVAVYDSATGQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -SGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELAIPERDTVINEIGELVFDGy ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI00126223D9 ---ALSAQVKSVEQTLGARVGVSVFIPSQGVVW-NYHGDQRFPMMSTFKTLACAKMLSDVD -AGKLALNDTVKVRSEDLMEYSPVLRPLAGTDITLQAACQATMETSDNTAANLVLEKIGGS -AALTAYLQSIGDNVTRLDRNEPTLNEAVKNDPRDTTTPNAINHSLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNTAIVAIGKSIFDTf ->[subseq from] Beta-lactamase class A n=3 Tax=Streptomycetaceae TaxID=2062 RepID=A0A3N1YHI5_9ACTN ---RLADSFRQLEREHGARLGVLAHDTGSGATV-RYRADEAFPLCSTFKPLAVAALMRAGD -----DLSARVHYTDADVADHAPVTGR--TRVLTVAELCAAAIEFSDNTAANLLLRRLGGP -TAVTRFCRSLGDPATRLDRWEPALNSAEPDRSTDTTTPHALARTFARLTLGDALARPHRA -RLTAWLRASTTGTHRLRAGLPPSWALADKTGTGSYGTANDLALAWPPHRPPLVLAVLSTR -PTAPAAPDEPLLARTAALLA--- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus chiguensis TaxID=411959 RepID=A0A1M5XC82_9BACI -----ESEFRLLEKAYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT ---LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELGDASIRYSDNTAANHILNRIGGP -NGFKKALRDIGDDVTNPERREPELNLVNPGEIKDTSTPKALATSLKAFTMGNVLPKEKQD -LLVDWLKRNTTGDHLIRAGTPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK -EGKNAEADDKLIAEATKKVI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. E740 TaxID=1834149 RepID=A0A1A3C559_9MYCO ------DRIGELEARHNALIGVFAVNLDTERTI-AHRAQDSFAMCSTFKGYAAARVLQKAE -RGELALTDRVTIERSDILPNSPVTETRVGQSMTLAELCEAALQQSDNAAANWLLRVLGGP -SAITDFARSIGDPRSRLDRWETELNTAIPGDLRDTSTPEAIGGGFRSILTGAVLAEPQRR -QLDEWMRANRT--SSVRPALPPGWTTADKTGSGDYASTNDVGIAYGPNGERLLLSIMTRT -AGPSTPNNRALIAELAGLL---- ->[subseq from] Beta-lactamase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PP91_9PSEU ----YTTDFAALEKRFDARLGLFAVDVTTRRTV-GHREEERFAICSVFKGYAAGALLKANP -LSSGFFKKTIKFAASDLVDGSPVTSTRVQSGMTVAELCHAAITRSDNTAGNQMLKLLGGP -TKLTEFARSIGDPMTRLDRWETALNVVPRGTEQDTTTPSAIAKAYQMLVVGDTLGAPERQ -QLKDWLVANTTGGERIRAGLPPTWVTGDKTGTGSFAAANDVAVTWPSPDKPIVIAVLTDK -AAEDAKYDSALLAEATKVAIK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia puraquae TaxID=1904757 RepID=A0A1X1PNH8_9BURK ---AAQAELTALEKASNGRLGVDALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEVVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGDTFFRLDHWEPELNNAAPGDERDTSTPVAMVDTLQRLLLGNTLQAPQRA -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. IS-1590 TaxID=1772286 RepID=A0A101BJS6_9MYCO ----VEDRLGEMERRQNALIGVFATDLGTGRTI-AHRAQDMFAMCSTFKTYAAARVLQKAE -RGELALTDRVTIEPGDIVPNSPVSEAHVGQTMTLAQLCQAALQRSDNAAANWLLRVIGGP -SGVTDFARSIGDQRSRLDRWEIELNAAVPADPRDTTTPEAIGAGYRSILTGDVLAEPQRR -QLDDWMRANQT--SSVRPVLPPGWATADKTGSGDYASTNDVGIAYGPVGERLLLAIMTRT -AAPDVPNDRQLVGYVASVLV--- ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149R5M7_9PROT ----VASVLSEYEDATGGRIGVYARNLVTGQAL-TWRENERFAVCSTFKASLVALVLLRVD -QGKERLEEVVPYTQADVEKYAPVAQAHVEAGLTVRTLCQAALEQSDNACANLLLARVGGP -AMLTRFWRSLGDAQTRLDDWEPVLNRTPPGGLRNTTTPRAMAGTLEHLLFGDTLSVSSRT -LLTDWLKGCRTGAHRLRAGLPEGWGVGDKTGNNGRDAVSDIAVAWAAPQRPIILSVYTRG -GHPVEEQFRTAFAGIGRMV---- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. P44RR-XXIV TaxID=1921145 RepID=A0A4T3FLA5_9RHIZ ----IAARFKKLEKRSGGRLGVAVLNTATGQLA-GNRLDERFAMCSTFKALAVAFTLSRVD -RGQEQLDRRIFFKEGDLVTPFKATKPHLADGMTIEQLCEAALIVSDSTAANLLLASFGGP -AALTGYLRSLGDPVTRLDRIELDLNIVKPGETHDTTSPRAMVATLQKIILGDALSAASRA -KLTNWMIASKDAAQRLRVGLPNGWRIANKPGTWNGISTNDIGVIFPPGRDPIVVAAYLGE -APGSIKDHEAILAEVARIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2G4ATK0_VIBSP ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. D-99 TaxID=2717316 RepID=UPI00141F896A ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARTSGDMTFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLHEPQRA -QLTEWMAGGARGATGIAAGVPPGWRIAGKAGTGGYGTTTDIAVLWPPSRAPIVMAVSFTQ -PQAAAAARADVVASAARIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=UPI000B7CC2DA -----TGRLRELERRHGARLGVFALDTGSGRTV-LHRADELFPMCSTFKTLAAAAVLRRDV --DGSLLGKVITYTQAEADKYAPITGANLANGMTVSALCEATITYSDNCAANLLLRELGGP -TAISRFARSIGDPVTRLDRYEPELNSAEPGRRTDTTSPRAIGQSYARLTLGHALDRPDAE -QLTNWLLANTTGGNRVRAGLPAEWGWGDKTGGGSYGTTNDVGIAFPPGRAPIVIATLSTR -ESPDGGADEPLLVKTAQLLAETf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI0010BD45F7 -------SIAKIESRISARIGVAVYDSATGQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTATPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIPERDTVINEIGELVFDEy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXJ0_9BACT ------AAAQATEKALGARVGVAVIDMADGASW-TYKARERFPMASTFKGLACGALLAAGA ----DVKARSVVIQKQELVPYSPVTETLVGKEVAAVDLCKATLRTSDNTAANKVLDILGGP -AKVTAFLRESGDDITRLDRREPELNEGKPGDDRDTTTPLAVATTMRNLILGDILKESDRA -QLTEWLVANEVGGPLLRAGVPSDWRIADRTGGGGFGTRGVVAVMWPAQGEPIVAAVYITE -TTATMDERNKAIAEIGRAIAT-- ->[subseq from] Class A beta-lactamase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A427M0A2_9BURK ------QAAQEAEQSLQARIGLAVLDTADGQLW-QYRADERFPMASTSKALICSALLARGP ----GAMKTAWLIKEEAIQSDAPTTENLIGHYVSAAQLCAITMRNSDNTAANGVLEMLGGP -QAVTSFLRTIGDTVTRLDRNEPSLNEATPGDLRDTTTPQAMVQTLQSLVLGDALKTPDRD -RLTDWLRHNEVGGPLLRAGVPESWTVADRTGAAGYGTRGVVAVMWPPERAPLVAAVYITE -TKASMEARNAAIAAIGKVIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BE76_9PSEU ---AVTTDFTALETRFGARLGLVAVDVTSGKAV-AHRENETFALLSVFKGYAAGALLKAHP -LDTGFFNQTIKYTKADLVDNSPVTEKHVDTGMTVAAICEAAITRSDNTAGNLMLKLLGGP -TKLTEFARSVGDPKTRLDRWETDLNVVPPGTEQDTTSPAAIGNAYRSLVVGDTLGVPERT -QLKNWLLASTTGAERIRAGLPSGWVTGDKTGTGGWGTANDVAVTWPSPDKPIVIAILTDK -KAKEAKPDNALLAEATRIAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis prasina TaxID=2015 RepID=UPI0005940F17 ---DFEAEFEALEEEFDARLGVYALDTGSGEEV-AFQEGERFAFASTFKALLAGVVLSGNS ---LEEMERVVTFDESVLVPHSPVVEEHLESGMSLLELCDATVRFSDNAAANLLLEEIGGP -EGFGSALEETGDDVTNPVRWEPDLNEAVPGDERDTSTPEALAGSLEAFTLGEVLPEDRRE -VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGGGGHGTRNDIAVLWPEEGDPILLAVLSSR -DVEDAEYDDALVAEATEVVVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. WL3 TaxID=2603277 RepID=A0A5B9FMS7_9RHIZ ---TMTAAAQAVETRLGMRVGFAVINTGGGETL-TYRADERFAMASTFKALACASALAGGQ ----AVLDKETRITKADLRPHSPVTEKRVGTSLSTRMLCEITLRTSDNAAANAVLAAIGGP -PALTTFLKGIGDGTTRLDRYEPELNQATPGDPRDTTTPKAMAETLRRLLLDDALEPGARD -QLEAWMAANAVAGGLLRAELPAGWTIADRSGAGGHGTRGVIALLRPPEGPPLVVAIYMDG -RKHPLKVRDAAIAEIGKAIFAEy ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00080EBF31 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNALLFGNTLNPQDKQ -TLKSWMMNNRVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] Beta-lactamase CTX-M-1 n=2 Tax=Legionella israelensis TaxID=454 RepID=A0A0W0VTP8_9GAMM ---ALKKKLAELESQSGGRIGLYAINTADNSHI-QYRANERFPTGCTSKVMGVAAVLQKSM -SEPLLLQKKLFYKQEELTNWNPVTEKHLSDGMTVEALCAAAISYSDNTAMNLLVKQLGGV -QVMNIFARSIGDTVFRQDHGWPEAMSGGLDNVNDSSTPKAMAKSLQRLALGHILAESQRQ -LLISWLQQNTTGEARIRAGVPKGWIVGDKTGTGMYGTTNDIAIIWPPKSAPIVLVVYFTN -DHKTAEKQESVIAQATKLVINAf ->[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. Sr59 TaxID=1259202 RepID=A0A4R9BYE7_9MICO ------AEFTTLEATYDARLGVYALDTGTGSEI-SWRDDERFAYASTIKAMAAAALLDTVG ---LAGLATPVPIEESDIVPYSPVTEPRVGGSMTLGEIAHAAMTVSDNTAANLMFEALDGP -TALDVDLSNLGDDTTVVSRIEPDLNEAVPGDDRDTTTPRAFATNLNEYLFGEHLSGGEKA -QLETWLTGTQTGDTLVRADLPTDWVVGDKSGSGGYGTRNDLALIRPPGRAPIIISVMSSK -AEPDAESDDRLIAEAAAAAM--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium elephantis TaxID=81858 RepID=UPI000629BC92 ---TVEAQIAALEVQHGALIGVYASNLDLQRTV-AHRAQERFAMCSTFKTYAAGRTLQMAE -RGELSLEQSLFVDPEDILINSPITEARAGGELTLAELCQAALQRSDNTAANMLLATLGGP -QAITAFARSIGDSESRLDRWETALNSAIPGDPRDTSTPQALGFGYRNLLAGDALAPPERS -RLEDWMRANQT--SSMRAGLPDGWTSADKTGGGDYGSTNDVGIAYGPDGQRVLLALMTRS -QTADAPGLRPLIGELTSLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0009C0D612 -----VQTAQMLEQSLGARVGLAVLDTADGHVW-QYRANERFPMASTSKLVICAALLARGP ----GAMKAAWRVRQEAVQSYAPTTKDRVGEQISADQLCAITMRNSDNTAANGVLEILGGP -AAVTSFLRSVGDTVTRLDRNEPSLNEAAPGDPRDTTSPYAMVQTLHRLALGDALKAAGRD -QLIGWLRRNEVGGPLLRAGVPERWAVAGRTGAAAYGTRGVVAVMWPPERAPLVAAVYITE -TQASMDERNAAIATIGKAIA--- ->[subseq from] Uncharacterized protein n=1 Tax=Enterovibrio pacificus TaxID=1080227 RepID=A0A1C3EMT1_9GAMM ----LSDTIKKVEQQTKGRVGVAVWDSRDNSWW-NYRGSERFPMMSTFKTLLCAKALHDIE -SGSLSSDASERIESKNLIPWSPITEQRVGQSMTVIEACEATMLTSDNTAANLALNLTGGP -SALTAFLIKQSDSTTNLTRFEPDLNTAIPGENRDTTSPEAMLRTLQKILLGNALTRKHRA -QILMWMKNNRVSDPLLRSVLPAGWQIADRSGAGGYGSRGVTALVWPNSDRKLMVSIYLTE -TKLDLTKRNKVLAEIGKAVFSNy ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. THAF192 TaxID=2587868 RepID=A0A5P8ZQN0_9MYCO ------PRIEALERREGVIVGLHAVDLPTGRRL-AHRAKDRFAMCSTFKGYAAAAVLSRVD -RGLLALTDTVTIAPAELVTYSPVTEPRVGQPMTLAELCQAAVQQSDNSAANALLRVLGGP -PAITEFARSIGDEVTRLDRWETALNSAVPGDLRDTSTPVALGTGYRALLAGDALAGSSRQ -TLQDWMRANET--SSMRAGLP-GWTTADKTGSGDFGTANDVGIAYGPQGQQLLLSIMTRS -AGPEAPSRRDLIGELAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 17J27-24 TaxID=2555898 RepID=A0A4Y8ZX04_9SPHN ------AALEAIRATLGARLGVAAIDTATGSRL-LFDADSRYAMCSTFKAPLAAAILSAAE -RGTLSLDEEIAFGPADLLDHAPVVRANLAKPLPVRTLCAAIVEVSDNSAANLLLARIGGP -AGLTRFVRAAGDSVTRLDRTEPELNSNLPGDPRDTTSPAAFAALIQRLVLGDVLRPASRD -LLAGWLRSASTGLDRLRAGLPQGWTAGDKTGTGN-GANNDVAVAWRPDGSALVIASFTNG -DA-PAGVRNAAHAEVARLVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. AC27/96 TaxID=1841653 RepID=A0A1B9RYW7_9RHIZ ----IAARLKKLEKRSGGRLGVAVLNTATGQLA-GNRLDERFAMCSTFKALAVAFTLSRVD -RGQEQLDRRIFFKEGDLVTPFKATKPHLADGMTIEQLCEAALIVSDSTAANLLLASFGGP -AALTDYLRSLGDPVTRLDRIELDLNIVKPGEIHDTTSPRAMVATLQKIILGDALSPPSRT -KLTNWMIASTDAAQRLRVGLPNGWRIANKPGTWNGISTNDIGVIFPPGRDPIVVAAYLGA -APGSIKDQEAILAEVARIVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia multivorans TaxID=87883 RepID=B9AZR0_9BURK ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLTEWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=UPI001377FBAA ---AMTQFLQQQEKRLNARIGMAVVNAQGEPVF-GYRQDERFPLTSTFKPLACAALLARLQ -KDGGSLDQQVTIQPDELLDYAPITKNYLAPSLSLRMLCAAAVSYSDNTAGNRILTYLGGP -GAITSFMRRLGDNVTRLDRTEPALNEATPGDARDTSSPKSMALGLQKMLTSNTLTPTNRA -TLAGWMREDKVGDALLRATLPPGWAIADKTGAGGHGSRAIIAAVYPPQQAPFYVAIYLTR -TEATMEMANTAIAQIGERLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A37856D ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---VAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEGLGGP -TELDAALTALGDDTTVVSRTEPDLNEAIPGDERDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPAEWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK -DQQDAKADDALISGAAKAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI000CFE7B27 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRGAGGYGTTTDVAVPWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARSVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251Y7K2_9MICO ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---VAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEGLGGP -TELDAALTALGDDTTVVSRTEPDLNEAIPGDERDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPAEWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK -DQQDAKADDALISGAAKAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sinensis TaxID=2302434 RepID=UPI0014023836 ---QAEKAIKMQEETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD -QERNELSQTVTVSSDDLVTYSPILEAYAEKEITLGDSCQATMLTSDNTAANIIIESVGGT -ESITSFLRDIGDMNTRLDRVEPELNEALPHDLRDTTTPISMTKTLSELLFGPVLSQDSRV -QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGSRSITAVVWRDKQSPLIVSIYVSQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas japonica TaxID=511662 RepID=UPI00111D25E7 ----ARDALRDIARASGGRLGVFAYDTGTGRRL-SLDAGARYALCSTFKAPLAAAILAQVD -AGRLTLDRTIRFGEADLLGYAPVVRENLATGLSVERLCRAAVEVSDNSAANLLLPQLGGP -AGLTRWLRSIGDPATRLDRDEPTLNIVRGGDLRDTTTPMAIAMTIDRLLFGDVLMPQSHA -LLQRWMAASTTGRARLRGGLPADWQCGDKTGTSGEGCFNDVAFAIPPGRKPIVIACYLDA -AGLSDANANAAHAAVGELVGQVf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=UPI0013DF1AC6 ---SAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTIFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRAAAKRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIASAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X2C3_9BACT ---------ENIEERLDARVGLLIRDSGTGWSW-GHRADERFLMNSTAKVPLCGAVLAQVD -KGAMRLTDGLDVRAEDMVEYAPVTELRIGDTMQVGELCFAALDMSDNAAANILIDHLGGP -QEVTAFMRQIGDDVSRLDRREPDLNRFETGDPRDTTSPAAVVDTPERLLVGDALSPSSRA -QLTEWMTPGGVTGALLRAFTPDSWRVADKSGSGSV-TRNIVGMIAPPQGGPYFVAIYLSE -AEADFDTRNAAVVAISAAVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. capsici TaxID=1874630 RepID=A0A0M4HV79_9MICO ---AADAAFAALEERFGARLGVHAVDTGSGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALAALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERA -LFTGWLKATQTGGTLVRAELPADWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK -DQQDADADDALISGAAKAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000D007B51 -----RSELAALDKASNVRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPELNRATPGDERDTSTPVAMVDTLQRLLLGDTLQQAQRA -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAVSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sinensis TaxID=2302434 RepID=A0A3A6R2Y4_9VIBR ---QAEKAIKMQEETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD -QERNELSQTVTVSSDDLVTYSPILEAYAEKEITLGDSCQATMLTSDNTAANIIIESVGGT -ESITSFLRDIGDMNTRLDRVEPELNEALPHDLRDTTTPISMTKTLSELLFGPVLSQDSRV -QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGSRSITAVVWRDKQSPLIVSIYVSQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3L0W1F9_ECOLX -------KVNSYEN-QGWSIGVTVFDTKSGKRE-SVHGEKRFHFNSTIKALACANVLAKVD -KGQLALDDFIELKKKDIVTYSPVTEKLIGKKLTLRDACEATLTYSDNTAANYAISSVGGP -DGLTAFMRSIGDNALRSDRYEPDLTKNIEYDIRDTTTTDAMAQSLYRILLQDVLSEKSRT -QLKKWMEGNKVADDLLRASLPDGWFIADRSGASDYGVRGIISIVWSENRQPLVIAMYVRK -DGSSMSERDKVISDIGATIFSSy ->[subseq from] class A beta-lactamase n=2 Tax=Legionella israelensis TaxID=454 RepID=UPI001072CD31 ---ALKKKLAELESQSGGRIGLYAINTADNSYI-QYRANERFPTGCTSKVMGVAAVLQKSM -SEPLLLQKKLFYKQEELTNWNPVTEKHLRDGMTVEALCAAAISYSDNTAMNLLVKQLGGV -QVMNIFARSIGDTVFRQDHWSQEAMSGGLDNVNDSSTPKAMAKSLQRLALGHILAESQRQ -LLISWLQQNTTGEARIRAGVPKGWIVGDKTGTGMYGTTNDIAIIWPPKSAPIVLVVYFTN -DHKTAEKQESVIAQATKLVINAf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio chagasii TaxID=170679 RepID=UPI0010CA9497 ------ESIEQIESRVSARIGVAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDAE -NKGLDLDSKVSIKSEDLIVWSPVTKELVDKGISLRDACSATMTMSDNTAANIVLGGIDGP -NGLTEFLRSIGDSNTRLEHLEPELNHARPDDARDTTTPKSIVMTLNELMYGDTLSQASKS -TLKGWMMGNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRDPLIISVALTE -TEFTLQERDKVINEVGQLIFDTy ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001366628E ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDAKADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis subsp. chilensis TaxID=1523530 RepID=A0A399TAD1_9MICO ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRAEPDLNQAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDVAVIWRPDAAPIVIAIHSSK -DQQDADADDALISGAAKAAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=UPI0011B2517F ---AVQARFAQLEESFDARLGVFAVDTGSGRTV-VHRGDERFGFASTYKALAAGALLERTG ---DAELDAVVTWTADEVVAHSPVTGQHTASGLPLRQVAEAAVTVSDNTAANVVLAHLGGP -AGLEEDLRALGDDTTEVEHTEPDVNDITPGDPADTSTPRAMATTLQAYATGDVLAPAGRD -QLVRWLQAGTTGGGQIRAGVPAGWVVGDKTGHAGYGNQNDIGVVWPTGGAPWVLAILTDR -ADVDATSDEALLARATEVVVDE- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium fluoranthenivorans TaxID=258505 RepID=UPI0014240298 ----LDQQIGALERRHNAVVGLSAVNLNSPGTV-AHRPDQMFAMCSTFKAYAAGRVLEQVG -RGELSLEATEFVDPSAVVANSPVTGPRAGSQMTLAELCQAALQRSDNTAANLLLRRLGGP -PAITAFARSVGDDRTRLDRWETELNSAIPGDPRDTSTPAALAGGYRALLTGDVLAPPQRL -LLEQWMRANQT--SSMRAGLPTGWTTADKTGSGDYGSTNDVGVAFGPEGQRVLLAIMTRS -AADDADALRPLIGELTTL----- ->[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q84EY1_ATLHE ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDPVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANEAIPAIGKQLF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=A0A0C2ANI9_9ACTN ---TLTEQFRALEQEYAARLGVFALDTASGATV-GYRAQERFPMCSVFKGLAAAAVLRDVD -RHGEFLARRIRYTAEFVEAYIPVTGKNIAHGLTGAELCAAAVSESDNGAGNLLLRELGGP -TAITRFCRSLGDGTTRLDRWEPELNSAEPWRIEDTTNPRAVGMTYGRLLLGGALSPGDRK -RLWEWLVANTTNTERFREGLPADWILADKTGGGEYGVANDVGVVRPPGRSPLVLSILSTK -YDPQGPTDNPLVARAAAIVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycetocola saprophilus TaxID=76636 RepID=UPI00068F6A5A ----------------------FLIDTGAQRTV-EYRADERFAFASTIKAHQAAAILQTRE ---IAALQEHVTFTAEQIVSYSPITEQHFEDGMLLHEVVTAALQYSDNTAANLMFDRLGGP -SGLQQLLRESGDHTINVDRIEPDLNEATPGDPRDTTTPRAHAHTLARFGISDHLPAEKRE -LLTGWMKANTTGGELIRAGVPADWVVADKTGGGYYGTRNDIAILWPPTGAPLVLAVMSSK -DAQDAEYSNALIARATTQA---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodopseudomonas palustris (strain BisA53) TaxID=316055 RepID=Q07QH1_RHOP5 -----PSALQTYERESGGRIGLYAENLATGTKI-AWRADERRVMCSTFKASLAALVLARVD -RGEDRLDDIISYSAADLLDYAPVARENLAKGISVDEMCKAMVEFSDNTFANLLLARVGGP -AALTGFWRATGDSISRLDHNEPELNFPPPGDPSNSTTPIAMAGTLRRVVLGEVLTPASRD -RLIGWMVNCKTGANRLRAGLPTDWKIADKTGNNGVDAAGDIAVAWPRANAAVVICAYTQG -GTPTKAQLETVFAAIGRMVG--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium chlorophenolicum TaxID=37916 RepID=A0A0J6YBQ7_9MYCO -------DLTAVEDRTGARIGLYAMELGSGAAL-AHRAAERFAMCSTFKTYAVARVMQLAE -SGHQPLDASLPVVDADIVENSPVTSARVGGSMTVEEVCAAALIRSDNTAGNLLLRRIGGP -PAITAFARSVGDNESRLDRWETELNTALPGDLRDTTTARALASGYREVLTGSALTDAARN -RMLGWMAANETSQKRFRAGLPGGWTSADKTGAGDFGSTNDAGLLIGPEGQRIAIAVLTRS -RDPDAEPFNDAIAEAVRLAIARf ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1C8JYW2_PROMI ------NSIKEVEQNLGAKVGVSIYSVSDGYLW-HYNGDSRFPLMSTFKTLACAKLLHDVE -TAKLSIDRSVKIEEQDLITWSPITEKLVGESFSLKQACTAAMVMSDNTAANIVLDGISGP -SELTLFMKELGDEVTRLDRIEPHLNEARSGDERDTTTPNAIVKSLGKLLYGEKLSSGSKE -QLIEWMAGNKVSDSLLRSVLPEGWSIADRSGAGGFGSRGITAAIWSNEQQPLIVAIYLTQ -TEASFDERNKAIAKIGREIFASy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces virginiae TaxID=1961 RepID=A0A2D1BXP5_STRVG ------RRLRDMEREHGARIGAYARNLATGRTV-AHRAEELFPVCSVFKPLAAAAVLRDLD -HDGEFLARRVHYTAAEVDAWTPVTQDHVADGMTVEALCAAAVSQSDNLAGNLLLRELGGP -TAITRFARSLGDRVTRLDRWEPALNSAEPWRTEDTTNPRAIGETYARLLLGDVLPRGDRD -RLTGWLLANTTNTHRFKEGLP-GWTLADKTGGGDYGVANDVGVVWSPAGVPVVMAVLTTR -PQAPGPNDSELVAETARLL---- ->[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium OV320 TaxID=1592329 RepID=A0A0N1GYN8_9ACTN ----------------------FAYNVRTGRSV-RYRAAERFPVCSLFKTLAVAAVLRDLP ---EGTLDRRVFWTSTDVVENSPVTQDHVADGMTIAELSAAAIQRSDNTAGNLLLRELGGP -TAITRFARSVGDRVTRLDRWEPDLNSAEPDRVTDTTTPYAIGRTYARLVLGDALAPADRR -RLTDWMLGTITSANRFRAGLPPTWTIADKTGGGWYGANNDAGIAWTPDGAPVVLAVQLTK -PDREAAYDNELIVKTAEVLAE-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Ralstonia TaxID=209769 RepID=A0A100I051_9RALS ----LQQATQREEEALNARIGVAVIDKESGMTW-SYRGDEAFPINSTHKAYLCAALLEKVD -QKQLALSDRTTLSKRDLVAYSPITETLLPPQASNAQLCEAAVSYSDNTAANKVLETIGGV -EGFNGFMRSIGDQKTRLDRKEPELNEGTPGDPRDTTTPVAAVRSLDQIFFSDHLSRSSKS -ELKTWMVNDKVAADLLRKSLPAGWDIADKTGAGGYGSRSIVAVVYPRGKKPLLVSIYITQ -TKATLGESNAAIARMGAILFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora niveoalba TaxID=46175 RepID=UPI000A06B2C0 ---KVRKDLRKLEASFKGRIGAYALDTSTGKTV-TYRAGERFPLLSTFKAPLCAAVLHKAR -TKPGLMDTVVKWTAADMKPNSPVTEKHIKDGLTVAQLCEAAMTQSDGTASNLLLKQIGGP -AGLTRYFRTLNDRTSRMDRWHPGLNNWAPGEKRDTTTPAAIGRDLRALTTGTALHAKDRQ -QLITWLLANKVGGERIRAGLPTTWTIGDRTGTNSFGGGNDIAVIWPAKGAPVIMAIYTNR -TP-GLATDNRTIAKTAAILA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SA88_KLEPN ----------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Salmonella enterica I TaxID=59201 RepID=A0A3U9Q9E2_SALET ---SIDDTVKQVETTLGAKVGIAVLDTGSQRAW-FHRADDRFPMASTSKALTCAALLDK-- --GQSFMNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGP -QAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLGSDERK -QLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGDGTRGVIAVMWPPKHAPIIAAIYITQ -TKATMEERNAAIASIGKAIAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Legionella israelensis TaxID=454 RepID=A0A516MY49_9GAMM ---ALKKKLAELESQSGGRIGLYAINTADNSYI-QYRANERFPTGCTSKVMGVAAVLQKSM -SEPLLLQKKLFYKQEELTSWNPVTEKHLSDGMTVEALCAAAISYSDNTAMNLLVKQLGGV -QVMNIFARSIGDTVFRQDHGWPEAMSGGLDNVNDSSTPKAMAKSLQRLALGHILAESQRQ -LLISWLQQNTTGEARIRAGVPKGWIVGDKTGTGMYGTTNDIAIIWPPKSAPIVLVVYFTN -DHKTAEKQESVIAQATKLVINAf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3DC896 ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHTIAMDYQQVVLGDALLPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Arthrobacter sp. MDT2-14 TaxID=1258920 RepID=A0A3A5NI64_9MICC --kDLVAALRNLETRYDARIGVFAKEGLDGKSF-AWRADERFAYASTYKALAAGALLDKFG ---TDILDTTVQIPEGDLVEYSPVTEQYAGQEMTVRQVAEAAVRTSDNTAGNILLELLGGP -HGFDEELEHLGDTTTRADRFEPELNEATPGDPRDTSTPAALAQDLQAYVAGDELSTEERA -LLTKWMSANATGDTLVRAAVPEDWIVIDKSGAGRFATRNDIAIVTPPDEPPVTIAILTSR -SAEDATRDDDLVVDTARLVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000E32503B ------ESIEQIESRVSARIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE -NKGLDLDSKVNIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIDGP -NGLTQFLRSIRDSNTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASKA -TLKGWMMDNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVSLTE -TEFTLQQRDKVINEVGQLIFDTy ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL64 TaxID=2603894 RepID=A0A5C8T7G6_9RHIZ ---ETAPTLAEIERRLGGRLGVSAG-TRDRVLL-SHRADELFPMCSTFKAVAVAAILARVD -AGSESLDRVVDFGPDILLSYAPVTRKVVEAGMSISDLCAAAIVWSDNSAANLLLTALGGP -EALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTSPEAMRQTLGRVLLGPVLSAASRG -RLEAWMIACQTGAKRLRAGLPPDWIVGDKTGSGDNGTFNDVAILRPPGSAPVLACVYVTG -ATAPAPAVESAYAEIGRLIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0014284421 ---AADAAFAALEERFGARLGVHAVDTGTGTEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERA -LFTGWLKATQTGGTLVRAELPADWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK -DQQDADADDALISGAAKAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL1 TaxID=2603276 RepID=A0A5B9F9C9_9RHIZ ---ETAPTLAEIERRLGGRLGVSAG-TRDRVLL-SHRADELFPMCSTFKAVAVAAILARVD -AGSESLDRVVDFGPDILLSYAPVTRKVVEAGMSISDLCAAAIVWSDNSAANLLLTALGGP -KALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTSPEAMRQTLGRVLLGPVLSAASRG -RLEAWMIACQTGAKRLRAGLPPDWIVGDKTGSGDNGTFNDVAILRPPGSAPVLACVYVTG -ATAPAPAVESAYAEIGRLIA--- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A2S5VUX3_9MICO ---AADAAFTALEERFDARLGVHLVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADVLSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTSLGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLQATQTGNTLVRAELPTEWTVGDKSGSGAYASRGDVAVVWRPDTAPLVIAIHSSR -DAQDAEPDDALISGAARAAVQ-- ->[subseq from] Beta-lactamase n=2 Tax=Enterovibrio norvegicus TaxID=188144 RepID=A0A1I5NMS1_9GAMM ------------EETLSARIGVAVLNVESGALY-SFRGDERFPLTSTFKSIACAKLLYDVD -QKRTELNNTVAVNSDDLVTYSPILEAYVEKEITLGDSCQATMLTSDNTAANIVIESVGGT -ESITSFLRDIGDVNTRLDRVEPELNEALPGDPRDTTTPISMTNTLNKLLFGTVLSQDSRV -QLIDWMKRNEVTGNLLRSALPSGWEIGDRSGAGGFGARSITAVVWRDKQSPLIVSIYVSQ -TDASMDQRNLAIVEIGKSIFDLf ->[subseq from] Beta-lactamase Toho-1 n=2 Tax=Legionella feeleii TaxID=453 RepID=A0A0W0TUA4_9GAMM ----IQEKLAKLEASSGGKIGIYAINTANGQKI-HYRANQRFPMGCTSKVMGVAAILKKSM -SDPTLLSQRISYTKKDLTNWAPIAEKHLNTGMTVAELCAASISYSDNTAMNLLVKKLGGL -EKINDFARSIHNDTFRQDNGWPEAMSGGPNNVYDSSTPKAMAQSLQQLALNNVLAKPQHE -LLLSWLKSNTTGDKRIRAGVPKGWIVGDKTGTGMYGTTNDIGVIWPPQCSPVVIAVYYTN -NNKEAIQRNDIVSSATRLVIDGf ->[subseq from] Beta-lactamase n=1 Tax=Rhodobacterales bacterium TaxID=1948890 RepID=A0A2G6IKV1_9RHOB ---DTRAELESIEQRLSARIGVYAENLRTGQAF-EHRPDERFAMCSTFKASLAALCLSRSD -QGQLDLDERLAFGGTEILPTSPVTQNNLAAGMSISDLCQAIIEYSDNTAANLLLTHIGGP -AAMTQFFRDIGDTTSRLDRVELALNSNTEGDERDTTSPRAMARTLSQLTMANVLSDQSRA -RLIQWMRNEQNGRNRIRAAVSGDWTVGNKPGTSSNGAANDIAVLWSPDGIPFVVTVFIDA -ERGRTREAVGSIREVAGLALD-- ->[subseq from] Beta-lactamase n=1 Tax=Microlunatus soli TaxID=630515 RepID=A0A1H1WXJ7_9ACTN -------DLARLEATYRTRLGVYAFNVRTGRTL-CHRPNERFPIASVFKTLAAAAILRDHD -RHGEVLASRRYWTAEEVVDASPVTEKHVADGLTVAELCEAAITQSDNTAANEMLKIIGGP -RGLTRFARSIGDRATRLDRWETELNSAIPGDLRDTTTPQAIAASYAELALGHVLIRRDRH -QLLDWLLHNQTSAERFGAGVPDGWPLADKTGSPAYGGLNDVGITWTPAGTPIVMAGLSVT -DRPDAVIDPALMADVARLCC--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium attenuatum TaxID=2341086 RepID=UPI000F03A102 ------KQLEELEHTFDGKIGVYAINTSNGEII-AHREDERFPLQSTIKFMGVAALLKQSD -TDSHLLQEIVHYSQNDLIEWSPITRKNITGGMTLEALSEAAISYSDNAAINIIMKRLGGP -PAVAQFAHSVGNQTYNVEHYDGALNSD-PTSGADTSTPRDMAASVQKLSLGDGLTPAQQT -QLLGWMRNNTAGYRRIRAGVPGGWVVADKTGSGDYGIANDIGILWSPYCKPIVLAIYTVQ -NQRDAKRREDIVASATSIVLDQf ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A3B9YWT8_9PROT -----QTRFKVIEASAGGRLGVAILDLAFGATI-GTRLNERFALCSTFKLPLAAAVLEAAD -KGQLSLDEIIPYTKADLVFHAPVTGPNLAKGLTIRALAEAAQLTSDNVAANLLIKRLGGP -QAVTAIWRRWGDPATRIDRYEPEMNLVKAGDVQDTTTPEAIAMMVAKLCTEDVLKPASRE -MLIDWMIRTQTGLKRLRAGFPKQWRAGDKTGTMNGNKVNDVAIVWPPRRAPVIVAAFYES -PYDTRDQDQAILAQVGRIAAD-- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium shigaense TaxID=722731 RepID=A0A2S9R1J6_9MYCO -----DDRLGEWERRYNAYVGLFATDIASGRTC-AHRADDPFAMCSTFKAYTAACVLQKAQ -RGELELQQPVFIDPSGLLPYSPVTAPHAGSTLPLAQLCAAALQRSDNVAANLLLREIGGP -QAITDFARSVGDDRTRLDRWEPDLNSAIPGDLRDTSTPRALGGGIQKLLTGTVLDDAHRS -QLEDWMRGNVT--STMRAGLPAGWTTADKTGTGSYGSTNDVGIAYGPAGQRVLLSLMTRS -ASPDADGLGPLIADVTAAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium PA1 TaxID=2015569 RepID=A0A257HN71_9PROT ----PTAELAALEAKSQGRLGVGILDTASGELV-GHRQDERFALCSTFKLPLAAEVLRDVD -AGKRTLDQFIPYSKPDMVAHAPVTEANLAAGMAIGELAKATQITSDNPAANLILREFGGP -EAMTQRIRAAGDPVTRIDRYEPMMNRVVGDDPRDTTSPAAMARLVARYLTTDYLSQASRD -LLIGWMIETHTGTKRLRAGLPVDWKAGDKTGTAMTDKYNDVAIVWPPGRAPLIIAAYFNT -NIDMRDEFQAVLAEAGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Ralstonia insidiosa TaxID=190721 RepID=UPI000CEDBC3A ----LQQATQREEEALNARIGVAVIDKESGMTW-SYRGDEAFPINSTHKAYLCAALLEKVD -QKQLALSDRTTLSKRDLVAYSPITETLLPPQASNAQLCEAAVSYSDNTAANKVLEKIGGV -DGFNGFMRSIGDQKTRLDRKEPELNEGTPGDPRDTTTPVAAVRSLDQIFFSDHLSRSSKS -ELKTWMVNDKVAADLLRKSLPAGWDIADKTGAGGYGSRSIVAVVYPRGKKPLLVSIYITQ -TKATLGESNAAIARMGAILFK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A2Z2Z5Q0_9BACT ---DLDQTIEALENRLDARIGVAIHDTGTGKVW-GHREDERFLMNSTIKVPLCAAVLSRSD ----VDLSEELPVRAEDILEYAPVTEQHVGGTMTVADLCFATIDQSDNTAANLLFGRLGGP -ESLTTFLRSIGDDLTRSDRLEPDLNIWSAGDPRDTTTPAAMVRTLEAMLTGDALTATARE -QLADWMRPGGVTGALMRPSVPHNWDVADKSGSGSN-TRNLIAMLTPPDGAPIFVSLSISE -AEVDFATRNAALVELSAAVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus sp. Bac330 TaxID=2419841 RepID=UPI000EF48C00 -----ESEFRLLEKAYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT ---LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP -NGFKKALRDIGDDVTNPERMEPELNLVNPGEIKDTSTPKALATSLKAFTMGNVLPKEKQD -LLVDWLKRNTTGDHLIRAGTPIGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK -EGKNAEADDKLIAEATKKVI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium celeriflavum TaxID=1249101 RepID=A0A1X0C3A2_9MYCO -----DARIGEFERQHNALIGVFAVNLDTGQTI-RHRAQEPFAMCSTFKGYAAARILQKAE -RDELALSDRVTIDQTDIVPNSPVTQTRVGQTMSLAELCEAALQRSDNAAGNLLLRAIGGP -PAITDFARSIGDQRSRLDRWEVELNAAVPGDPRDTTTPEAIGGGYRSMLTGAVLAEPQRR -QLEDWMRANQT--SSVRPALPPGWTTADKTGSGDYASTNDVGVAYGPDGRRLLLALMTRS -AGPNAPNMRPLIGELAALLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium arabiense TaxID=1286181 RepID=UPI00138B9E5C ---SIEDRIGALERQYGAFAGVYAENLDNGRSV-AHRADDAFAMCSTFKAYAAARVLQKAA -RGELNLTDAVTIEASDILPNSPITETRVGRNITIEELCVAAVQRSDNAAANWLLRVIGGP -SRITDFARSIGDDRSRLDRWEIELNSAVPGDPRDTSTPRALGGGFRSLLVGDALGEAERR -RLDDWMRANQT--SSMRAGLPQGWATADKTGSGDYATTNDVGIAYGPDGQRLLLAFMTRT -QSPDAPTLRPMVGELAALVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066C2DE3 ---QVAKELRKLEVSFKGRIGAYAIDTATGRTV-TYRAHERFAMLSTFKAPLCAAVLQRAR -TSRGLMGKVVKWTAADMKPNSPVTEKHLKDGLTVSQLCEAAVTQSDGTASNLLLKQIGGP -AGLTRYFRALKDSVSRMDRRHPELNDWTPKEKRDTTTPAAIAADLRALTTGNALHAKDRD -QLNAWLLASKTGAERIRAGLPRNWTIGDKTGTNSFGGGNDIAVIWPGKGAPIVMAIYTNR -TP-GLATDNRTIARTATALA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. USM B20 TaxID=1571773 RepID=A0A4V8GAK5_9BURK ----AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQAGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIALAVSFTQ -PRADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Corynebacteriales TaxID=85007 RepID=A0A448HUD6_MYCFV ----IEDRLGEMERRQNALIGVFATNLGTGRTI-AHRAQDPFAMCSTFKTYAAARVLQKAE -RGELALTDRITIEPGDIVPNSPVTEAHVGQTMTLAQLCQAALQRSDNAAGNWLLRVIGGP -SGVTDFARSIGDERSRLDRWEIELNAAVPGDPRDTTTPEAVGNGYRAILTGNELAEPQRR -QLEDWMRANQT--SSVRPVLPPGWATADKTGSGDFASTNDVGIAFGPAGERLLLAIMTRT -AAPDVPNDRQLVGEVASVLV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2DD60_STRVZ ---RVTTRLRQFEREHSARLGVYARNLATGRTV-AYREDELFPMCSVFKGVAAAAVLRELD -EDGEFLAQRIRYTAKYVEDYGPETGKDVNNGMTVEALCAASVSHSDNAAANLLLEELGGP -TAVTRFSRSIGDRVTRLDRYEPQLNSAEPGRVTDTTSPRAIGRTYARLILGDVLPARDRR -LLTGWLIANTTNTDRFRKGLPADWILADKTGGGQYGVANDVGVVWTPDGTPLVLAVLTTK -PGPTGPRDSELVRRTAELLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1A6BI01_MYCGO -----DTELAALEERYNTSIGLFGLNTASQRAL-AFRADDMFATCSTFKAYVAAQILQQDQ -RGELRLTDTVYIDPAAAVPASPVTEPHIGGRMPLSELCAAAVRHSDNTATNLMLAMLGGP -ASVTAFARSVGDDRTSMVRWETELNTAYPGDPRDTTSPRAMGTGFLNMLTGDVLDAPHRA -QLQEWMRTIVTGDRRIRAGLPPGWSIADKTGSGDYASTNDIGVASGPHGERLVLAVMTRS -RSPNAVASETLIADVTRLAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Vibrio parahaemolyticus TaxID=670 RepID=A0A345N7N5_VIBPH ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADQSG----------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX8_STEMA -----ASDFAALEKACAGRLGVTLLDTASGRRI-SHRQDERFPMCSTFKSMLAATVLSQAE -RMPALLDRRVPVGEADLLSHAPVTRRHAGKDMTVRDLCRATIITSDNTAANLLFGVVGGP -PAVTAFLRASGDTVSRSDRLEPELNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAV----------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=UPI000D5D4DCC -----ESPFAAIERRSGGRLGVFAVDTGSGATL-AWRADERFLMCSTFKGMLAAQILARVD -AGHERLDREVRYTERDLIFTSPVTKANLAQGMTVGALCKAAVEVSDNTAAILLMRGAGGP -AALTRFMRDIGDDVTRSDRYEPASNQR--DGERDTTTPRAIVGSARKILLGDVLGAQSRQ -QLEDWMIASTPGRNRIRASLPPDWRAGDRPGTSVEGETNDYVIVRPPGRAPLVVATYYDA -PGLDMARREAVLREAGAAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2N7CAE4_VIBSP ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TQLTIQERDTVINEIGQLIFDAy ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. WYY166 TaxID=2656914 RepID=A0A5P9Z0E7_9ACTN ---QARKELRALEKKFGGRIGAYAIDTATGKTI-AYRSVERFPLLSTFKAMACAAVLHKAR -TEPGLMDKVVHWTAGEVKPNSPTTSKHVKDGLTVSRLCEAAITLSDNTAGNMVLKQIGGP -AGLTRYFRTLKDPLSRLDRWETELNDWTPKDRRDTTTPAAIARDLRAVTVGSALDARDRR -RLNAWLRATETGDARIRAGLPKGWTVGDKTGSNSFGGGNDIAVVWPGKGAPIVMAVYTHR -AA-GQAGDDTAIARTATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae TaxID=36814 RepID=A0A1X0IXI9_MYCRH --------LTPVEDRYSARVGMYALHLDSGASL-EHRADTRFAMCSTFKTYAVARVLQLAE -LGQRDLAETQPIAASDIVENSPVTSAHVGRSMRLDELCSAALINSDNAAGNLLLRCIGGP -PEITTFARSVGDDQSRLDRWETGLNSAAPGDPRDTTTPRALTTGYREVLTGRVLTERTRE -QMVGWMRQNATSTKRFRAGLPAGWTSADKTGAGSYGSTNDAGLLYGPRGQRIIMAVLTRS -RDPDAPPFNDAIADTVRLTLATf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium lentiflavum TaxID=141349 RepID=A0A0E4GXB2_9MYCO ----VDGRLAELERQYDAYIGLFAADLGSGRTC-AHRDDDPFAMCSTFKAYAAARVLQKAQ -RGELDLQQLVFIDPAALLPNSPVTAPQAGNTMPVAQLCAAALQRSDNVAANLLLAQIGGP -PAITDFARSIGDTRTRLDRWEIELNTAIPGDPRDTSTPRALGNGVQKLLTGTVLGDAQRS -QLQRWMRDNVT--SSMRAGLPPGWTTADKTGTGDYGSTNDIGMVYGPAGQRLLLSLMTRS -RSANADALRPLIVEVTKSV---- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00084C17D8 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTTITKEQIMPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -ALKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAB3_KLEPN ----------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=UPI00099BD2AD ---TLTEQFRALEQEYAARLGVFALDTASGATV-GYRAQERFPMCSVFKGLAAAAVLRDVD -RHGEFLARRIRYTAEFVEAYIPVTGKNIAHGLTGAELCAAAVSESDNGAGNLLLRELGGP -TAITRFCRSLGDGTTRLDRWEPELNSAEPWRIEDTTNPRAVGMTYGRLLLGGALSPGDRK -RLWEWLVANTTNTERFREGLPADWILADKTGGGEYGVANDVGVVRPPGRSPLVLSILSTK -YDPQGPTDNPLVARAAAIVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI00080DC41C ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Promicromonospora sukumoe TaxID=88382 RepID=A0A2U1EKE6_9MICO -----AAEIGRLEKKYDAVVGLYAVDTGTGVEV-AHRADDRFAYASTFKALAAAAVLDRSG ---PEELERVVTYGAGDLQAHSPVAERHLSDGMTMHQIIDAAVQESDNTAGNLLLDALGGP -QGLADALRAIGDETTKPARYEPELNDVTPGDERDTSTARALAHDLRAYGLGDVLDDDARA -TLVEALRGSVTGPETIRAGVPDGWVVGNKTGTSGRGGRNDIGLLWPPDGEPVVLAVLTRT -EDPEAEPDDALLAEVTEVAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAB2_KLEPN ----------RLERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0010F87F2D -------------RDRSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAC--------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000E66E78B ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRGDERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDATADDALISGAAKAAVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI000F564131 ----AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPQRA -QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIMLAVSFTQ -PRADAAARADVVASAARIAA--- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Pseudomonas salina TaxID=1323744 RepID=UPI0012386724 --qRVAQDVKAIGTSLSARIGISVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QEKVNPSSTFEIKKTDLVAYSPVVEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGP -EGVTDFLRQIGDKETRLDRIEPELNEAKLDDLRDTTTPKAIASTLNKLLFGSVLSETNQK -KLESWMVNNQVTGNLLRSVLPVGWNIADRSGAGGFGARSITAFVWSEHQSPIIVSIYLAQ -TEASMADRNDAIVKIGRSIFDVy ->[subseq from] class A beta-lactamase n=1 Tax=Malikia spinosa TaxID=86180 RepID=UPI001370AA46 ---TLSKAVQAEETRLGARIGMAVFDAKDGTRW-AHRGDERFPLNSTHKSFSCAALLKKID -RRVLALDNQISIERASLVTYSPVMEK-AGSQVSLREACAASVSWSDNTAANIVTDVIGGT -HAFTAFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIVLGDVLREDSRA -LLTDWMVNDKVADALLRASLPRAWSIADKSGAGGHGSRSIVAIIWPQNRNPFVVGIYITQ -TAAPMVDSNAAIARLGNVLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Cellulomonas shaoxiangyii TaxID=2566013 RepID=A0A4P7SM64_9CELL ---DLTAALADVEARHGVRLGVHAVDTAQGRTT-GHRADERFAFCSTVKPLAAAAVLAAR- --GVAGLDEAVPVTADDLVDFSPVTGERIGGTMTWRELGDAAVRYSDNTAGNLLLRDAGGP -TGLTAYVRGIGDDVTRSDRWEPGLNATAPGDERDTSTPRALAATYGTLVVGDALGARERE -VLADWLVRNTTGDALVRAAARPGWTVGDKTGAGAYATRNDVAVVWPPEGAPVVLAILTDR -PSPDAERTDAPLAEAAAVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium simiae TaxID=1784 RepID=UPI0003FF2EB2 ----FYDRLAELERQYNAYIGLFATNVGSGRTL-AHRDDDPFAMCSTFKAYAAARVLQQAQ -RGELDLQQRIFVDPAALLPNSPVTAPQAGNAMPLAQLCAAALQHSDNAAANLLLAQIGGP -PAITDFARSIGDQRTRLDRWEIDLNTAIPGDPRDTSTPRALGTGIQRLLTGTVLGEAQRS -QLERWLRDNVT--SSMRAGLPPGWITADKTGSGNYGSTNDVGMVYGPSGQRVSLSLMTRS -QSVDADGLRPLIAEVTKSVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycolicibacterium duvalii TaxID=39688 RepID=A0A2A7NHL2_9MYCO ----VEQRFEELQRRDNALIGVHAVNLDTGKTL-SFGDDRMLAMCSTFKGYAAAAVLQRAH -RGELALTDAVAVEAADLRPHAPATEPRVGTTMTLTELCVAAVQQSDNTAANLLLRTLGGP -QAITEFARSIGDDRTRLDRWETELNSAIPGDPRDTTTPRAIGTGYRNLLTGDALAPGDRA -LLEEWMRGNWT--SSMRAGLPDGWTTADKTGSGDYGTSNDVGVAYGPAGQRLLLSLMVRS -AGPDAPSLRPLIGELAALAVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A165PCU7_ECOLX -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMEN---------------- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B3DE277 -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAQLLQQQIGGGVITVLHGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAA------- ->[subseq from] Beta-lactamase Toho-1 n=2 Tax=Legionella donaldsonii TaxID=45060 RepID=A0A378JA20_9GAMM ----IQEKLAKLEASSGGKIGIYAINTANGQQI-HYRANQRFPMGCTSKVMGVAAILKKSM -SDPTLLSQKMTYTKKDLTNWAPIAEKHLNTGMTVAELCAASISYSDNTAMNLLVKKLGGL -EKINDFARSIHNETFRQDNGWPEALSGGPNNVYDSSTPKAMAQSLQQLALTNVLAKPQHE -LLLSWLKSNTTGDKRIRAGVPKGWIVGDKTGTGTYGTTNDLGVIWPPQCAPIVIAVYYTN -NNKEAIQRDDIVSSVTRLVIDGf ->[subseq from] class A beta-lactamase n=1 Tax=Bordetella genomosp. 13 TaxID=463040 RepID=UPI0011A24635 ----IEARLKALETRAGGRLGVAVLDTATGRLA-GSRLDERFALCSTFKALAAACTLARVD -RGQERLERRIFFTEQDLVMPFKATQPHLADGMTIGQLCEAAVTVSDSTAANLLLASLGGP -SAFTAYMRSLGDSVTRLDRMELGLNIVKPGETHDTTSPRAMAGTLREVMLGHALSEPSRK -TLTDWMTESRDAERRLRLGLPKGWRIANKPGTWEGISTNDIGVIFPPGRDPVVVAAFLAE -APGTIEQQEAVLSEVARIVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. ST5x TaxID=2100817 RepID=A0A2S9Q2Y9_9ACTN ---EVDRKLAALEKKYDAHLGVYAVDTGSGREV-GRHADTRLSYNSTFKALLAGAVLKRNG ---ADGMDRVLRYGKGDLLENSPVSEKHVKDGMSLRALSDAAVRYSDNTAANVLLKDLGGP -KALGALLRETGDRVSHVDRIEPDLSTWTPGEQRDTTTPRQQAANLRAFVLGDVLGAKERT -LLTGWLRANTTGDRTIRAGVPEGWVVGDKTGTGHHGARDDIAVIWPPGRAPLVVAIMSYR -DAKDAEPDDRLIAEAASVVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Methylobacterium sp. WL8 TaxID=2603899 RepID=A0A5C8WT22_9RHIZ ---SAAARIAAVEARLGGRVGVAFRD-APGVFL-GHRAGEAFAMCSTFKVLAAAAILARAA -AGAETLDRRIAYGAADLQSYGPVTRAALANALSVEALCAAAIVWSDNTAANLLLDALGGP -AALTAWLRGQGDAVTRLDRTEPTLNTALPGDPRDTTSPSAITGTLERCLLGDVLTPPHRA -RLEGWMVTCETSRTKLRAGLPLDWTVGDKTGSGDNATSNVVAILHPPGRPPIVAGLFLTG -SEAPPATRDAAHAEIGRILVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Acidipila sp. EB88 TaxID=2305226 RepID=A0A3P0XCK3_9BACT ------DPLQAMEHRYGGRLGVFALDLATGRTL-THRADERFLWCSTMKLPLVAAVLARVD -RGEERLDAPVHYMRQDLFPHSPVTEQHVAEGMSVEELCAAAMTVSDNGAANLLLRRIGGP -AALTRFVRSAGDAVSRFDRFELALNR--PSGELDTTTPRAAVMLLKSLVLGTALGAASRR -RLVEWLCATTVGVHRLRAGFPATWMVGDRTGTGDT-ETNDIAVAWPQGRRPILVAALYNQ -GEVSIDTREEAIRNIGSVIA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. BK558 TaxID=2512172 RepID=A0A4Q7Q7W3_9MYCO ----VTDRIDALRRRHNAEIGLYAVDLDSGREI-AVGDGDTYALCSTFKAYASAAILQRAQ -QGRLSLTDAVPVERTDIQPHSPVTEPRVGTTMTLAELCQAALQQSDNAAGNLLLRTLGGP -AAITDFARSVGDDRSRLDRWETALNSAVPGDPRDTSTPRALGAGFRAVLAGDALDGAHRQ -QLDTWMRANGT--SSMRAGLPAGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLAIMTRA -VGPEAPNMRELIGEIASVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia rhamnosiphila TaxID=426716 RepID=UPI000B0ADC1F ---DLSNTLMTLQAKYNVLFGIAAVDTRGGRTF-EWNADDRFALCSTFKVYAVAAILRLAE -RKQLDLNDKVPITRQDIVMSSPVVSDHVGELMSYYELSRAALVRSDNTAANLLLRRLGGP -GAVTEFARSINDSQTRLDRWEPELNEARAGDPRDTGTASALAAGYRKLILGDGLSTEYRR -MLTSWMRSSVTSRQRLRAGLPVGWVAADKTGSGAYGTANDAGVVWSPTGSSLVLVVFSRS -TTPMAAGADAAVADATAAVL--- ->[subseq from] Beta-lactamase n=2 Tax=Rhizobacter gummiphilus TaxID=946333 RepID=A0A1W6L9N3_9BURK ---DLSTAMTSLQARAGGKLGVFVQDTGSGDFI-SFNAESRFAMASTFKVLLAATVLQRVD -TGTVSLDQTVAFGRRDLLSYAPVTSRRVADGMSVRDLLAASLELSDSTAANLLLGLVGGP -SAVTDFVRGTGDVTTRLDRIEPDLNSNLAGDLRDTTTPIAMARTLQAVLLGRHLTIASRA -HLQAWMVAATTGKRRLRAGMPELWRVGDKTGSGDNGAFNDVAMAWPPAGAPLVFSVFMTG -ATAPPETLDAIHVVVARLAVR-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. 10N.222.47.A9 TaxID=1903178 RepID=A0A1R3ETV0_9VIBR ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2N7KUN2_VIBSP ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium phlei TaxID=1771 RepID=UPI00025AEDEC ------TAIRALEQRHNARIGVYAVNLATGRTV-THRAQEPFAMCSTFKTYAAARVLQMAE -RGELSLTDPVFVDPAAIVRHSPRTEPRAGGDMTLDELCQAALQISDNTAGNLLLQTIGGP -QAITAFARSIGDERTRLDRWEIALNSAEPGDPRDTSTPEAIGGGYRALLTGDAKGAPQRE -LLVRWMRANET--SSMREGLPAGWTTADKTGSGDYASSNDVGVAYGPRGERLLLALMART -AGPDAPTLRPVIGELAG------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3CG54_9SPHN ---KASARIAAIEARLGGRIGVSAIDTGSDAEI-NHRAQERFAMASTFKWLLAAGVLKRCE --EGLNLDAVMYFTPSDMLPTSPVTSAEISATLSVEQLCEAIVTVSDNAAANLLLVPMFGP -EGLTRFLRESGDPHTRLDRVEPELNENRPNDPRDTTVPHAMARTLRRLLTDEVLNANSRA -RLTGWMEKASTGLDRLRAGFPDGWRAGDKTGTGGNGSHNDCCIVWPPGRSPIVIASYLSE -SAAPNIEKAAAHAEIARIIVEDf ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000E3BE563 ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRXIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio antiquarius (strain Ex25) TaxID=150340 RepID=A0A657NBG4_VIBAE ----LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD -KNKISLDDSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP -EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL -QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK -SNTTMKERDQVIAEIGKVIFEQy ->[subseq from] class A beta-lactamase n=2 Tax=Saccharomonospora piscinae TaxID=687388 RepID=UPI0011067FD9 ---RVDAEFAKLERTYERRIGVLATNMRTGQSL-EHRPDERFPICSVFKVLLAAQVLRDLP ---VSVMDRRLTWSTDELVINSPVTEQTVRNGLTVAQLAEATVTVSDNTAANVLMREFGGP -AAVTGFARSLGDRVTRVDRWEPEMSTGTPGDERDTTSARAIARTYAALVLGRALDESARK -RLRTWMLANRTAGPVFGSGVPANWTLADKTGSGWYGVRNDVGITWTPDGSPLVIAAFTRG -TRYEDETLSEPLAEVAASAC--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000F4F1E6E ----LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD -KNKISLDDSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP -EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL -QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK -SNTTMKERDQVIAEIGKVIFEQy ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A510UGQ5_ALIFS ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNALLFGNTLNQQDKQ -TLKSWMMNNKVSDPLLRAILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. ES.045 TaxID=1528103 RepID=UPI000ADFE0D8 ----LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD -KNKISLDDSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP -EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL -QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK -SNTTMKERDQVIAEIGKVIFEQy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio fortis TaxID=212667 RepID=A0A5N3S4V8_9VIBR ---TLNDSIYSIEQRTLGRIGVSVLD-STDQRW-HYKGNERFPMMSTFKTLACAKMLQDSD -RDILDISTMAPVKSDELIAWSPITKNMVGSLITIENACEATMKTSDNTAANIVLKHIGGP -QGVTAFLRLTGDKVTQLDRFEPELNQAKADDLRDTTTPNAMNKTLHHILFEDVLAQNSKK -QLKEWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGITAAIWTDEREPLIISIYLTQ -TNLSMPERNQVINEIGKAIFEEy ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium marinum TaxID=1781 RepID=UPI000B979EFD ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYP ---IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDAWLPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVADAAKCVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea zeae TaxID=1642303 RepID=A0A5S4GTH0_9ACTN ---RARKDLRKLEVSFKGRIGAYAIDTATGKTV-AYRAGERFPMLSTFKAPLCAAVLQKAR -TAPGLMGRVVKWTAADMKPNSPVTEKHVKDGLTVGRLCAAAVTRSDGTASNLLLKQIGGP -AGLTRYFRTLKDSASRMDRWHPELNDWTPKDVRDTTTPAAISADLRVLTTGQALHDKDRE -QLNAWLLANRTGDERIRAGLPKTWTIGDKTGTNSFGGGNDIAVIWPGKGAPIIMAIYTNR -SA-GLPTDNQAIAKTAAILA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXI2_9BACT ----LKSVIESFEKNLGGRVGVALLDVRNASGW-YYRADERFPMASTSKALVCALLLKS-- --GPAALTKKVKVLESDILEYAPVSKTLTGQYVTASDLCAATMRTSDNTAVNKILDTLGGP -KAVTAFLRQIGNTSTRLDRNEPTLNEGRPGDVRDTTTPRAMAKTLQELIFGDTLNQQARS -TLINWLKGNEVGGPLLRAGLPNDWQIADRTGAGGFGTRGVVAAVWPTERSPVVIVIYLTN -TKASMDQRNAAIARIGREIA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. GA-2829 TaxID=1772283 RepID=A0A117JQ96_9MYCO -----ATELETLERANDVAIGVYAVNLDTGRTV-SHRAQESFAMCSTFKAYLAAHVLALVA -RGERSLDQGLYVAAADILPNSPRTEPRVGTEMTLGELSQAVLQVSDNAAANILLRDVGGP -QAITAFARGIGDPRSRLDRFETELNSAVPGDPRDTTTPEAIGGGVRTLLTGDVLPPEQRG -LLEEWMRANET--SSMRPGLPAGWTTADKTGSGDYGTTNDVGIAYGPQGERLLLSILTRS -ASADAENNRPLIGEVATVVFA-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. AT1 TaxID=1961706 RepID=A0A1V4PQH5_9MYCO -----GDQFAALERRYDAFIGTWAAALDGGRSV-ANRADDTFAMCSTFKAYAAGRVLQKDQ -TGALQLTDAVTIEAGDVVANSPVTEPRVGQNMTIGELCEAALQRSDNTAGNWLLRIIGGP -SAVTASARTLGDDRTRLDRWETDLNSAVPGDPRDTSSPRALGGGYQRLLTGDVLDAPHRA -QLERWMRGNQT--SSLRAGLPAGWTSADKTGGGAYGSTNDVGVVYGPDGRRAVLSIMTRS -RTDDAHDLRSLVAEVTTLVL--- ->[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium RIFCSPHIGHO2_02_FULL_39_13 TaxID=1798270 RepID=A0A1G0G3Y8_9GAMM --qTVSQKLNQLEIQNHVDIGLSAIETYNNTHI-NFNANKRFPMDSTSKVMTVAAILKKSE -SDPAFLKQRIFFTENDVRKYAPITSKYVKDGMTIFNLCAAALEYSDNAAVNQLMKIVGGP -NQVTQFARSIGDQKYFLVRWEPKLNSAIPNDKRNTTTPEAMADSVQKLVLGHALNNSQRA -LLRSWMKHCKTGDHRIRAGVPNDYLVADKTGTGGYGSIGDIGVIWRAHQSPVVLVVYVRQ -NEKNARTPDKVIAQATKILMN-- ->[subseq from] class A beta-lactamase n=1 Tax=Promicromonospora sp. PT9 TaxID=2219658 RepID=UPI00101B649E ----VGAAVRRLEERYDSVVGLYAVDTGTETEV-THRADRRFGYASTFKALAAGAVLERSG ---PEELARVVNYDADDLQEYSPVAERHVDEGMTMYQIIDAAVQQSDNTAGNLLLDALGGP -AGLQSALRAIGDETTRPARYEPELNDVVAGDVRDTSTPRALAHDLRAYGLGDVLDDEVRA -TFVEALRGSVTGMETIRAGVPEGWVVGDKTGTSGRGGRNDIGIVWPPGREPVVLAVLTQT -KDPEAEPDDALLAEVTAVAVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A2S5VDJ1_9MICO ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRGDERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRACALGDPLDADERA -LFTGWLKATQTGATLVRAELPTDWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDATADDALISGAAKAAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 02-925g TaxID=2022503 RepID=A0A260PTN8_9NOCA ----AEQNYLDLEARDAARLGVSAVDLATGSTD-SHRGDERFAFCSTFKVYAVGAVLAAAD -AGELQLTDTRTITEKDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -DALTEFARSLGDTEFRLDRTEPDLNTAIPGDPRDTTTPNSMAAGYRTLLHGDVLTPPSRD -QLLAWMADTQTSDARFRAGIPEQWTSADKTGTGSYGVSNDAGLLLGPDGQKILLVVLSTT -ASENSPAMNALVADTTRAVVDE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NDM6_9ACTN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTAGITVRELCSAAITMSDHTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAG--------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1X1VV64_MYCGO -----DTELAALEERYNTSIGLFGLNTASQRAL-AFRADDMFATCSTFKAYVAAQILQQDQ -RGELRLTDTVYIDPAAAVPASPVTEPHIGGRMPLSELCAAAVRHSDNTATNLMLAMLGGP -ASVTAFARSVGDDRTSMVRWETELNTAYPGDPRDTTSPRAMGTGFLNMLTGDVLDAPHRA -QLQEWMRTIVTGDRRIRAGLPPGWSIADKTGSGDYASTNDIGVASRPHGERLLLAVMTRS -RSPNAVASETLIADVTRLAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL94_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPXSXKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIDDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGE-------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=Q7M176_PROMI --rQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGKVNPNSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVGGS -KGVTDFLRQIGDK-TRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNKK -KLESWMVNNQVTGNLLRSVLPAGWNIADRSGAGGFGARSITAVVWSEHQAPIIVSIYLAQ -TQASMAERNDAIVKIGRSIFDVy ->[subseq from] RCP family class A beta-lactamase n=1 Tax=Yangia sp. PrR007 TaxID=2706884 RepID=A0A6B2N8U6_9RHOB ---ALRGTVARIEEQLGARVGLSLLDTGSGRSW-AHREDELFLMNSTVKVPVCGAILARSD -AGTLSLSDSLPVREADLVPYAPVMETRVGGTMTLDELCLAAVDQSDNVAANILIKHLGGP -EAVTQFFRSVGDPTSRLDRREPELNTFAPGDERDTTSPAAMSETLRALLLGDMLSPQARG -QLAEWMRHGGVTGALLRAEAEDDWLILDKSGSGRH-TRNLVAVIQPEGEAPWIATMFVSD -TDAAFEVRNAALKDLGRAVV--- ->[subseq from] Beta-lactamase AST-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645DSN7_9ZZZZ ---MLQQRLKALEARSGGRLGLSVQLAGGERGF-GYREDEAFPMCSTFKLLLAARILHLSQ -LGEFPLEQALLYEKNELVPYSPVTEKHADAEMTVRALCEAAVVQSDNTAANLLLTLQGGP -AGLTRWLRTAGDMRTRLDRTEPQLNSAVAGDMRDTTTPRAMARTSLALLTDKKLNPASQK -QLRDWLLASRTGDKRLRAGMPGDWIVGGKTGSGENGTANDVCIVWPTKGAPMVVSAYLTG -AKVDADGRNAILADVGHVVGDW- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A481SPE2_KLEPN --------------------------TCSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRX -QFVDWLKGNTTGNHGIRAXVPADWAVXDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHS--------------- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1N6KIG2_9BURK -----TNPISNIERRRGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLARVD -AGKENLDRLVHYTEKDLIFTSPVTKANVAQGMSVRAMCQAIVEVSDNTAATLLMRDAGGP -PALTQFVRGLGDTVTRSDRYEPDSNQY--SGARDTTTPKAITKSVGKILLGNVLSAQSRQ -QLESWMIDCEPGLDRIRAALPTDWVAADRPGTSVEEETNDYAIVRPPGRAPLLVAAYYDA -PYVDMDGREAVMREVGAAFVD-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JNW TaxID=2170731 RepID=A0A363RMC5_9BURK ---ALHKALTLIEAQSGGRLGVYAFDAETGGEA-GYRSDERFAMCSTFKTLLAAHVLYLGQ -TGALDLGQQVRVTSADMVPYAPVTEKYQDQPISLLELCEAIVVVSDNVAANLLLRASGGP -EALTAWLRTLGDKATRLDRIEPLLNTAAPGDPRDTTTPRAMQATLQALLLGDVLKGYGRA -MLQQWLSDSRTGDQRVRAGLPSEWRVGGKTGAGAHSTANDCLIAWPNAAEGLIITAFLTG -GERTTAQSDAVMAKVGAAIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=A0A2P1WN90_9BACI ----------------------------TGIIF-AYRAEERFAFASTYKALAAAIMLKQNS ---MEELNEVITYTEDELVTYSPVTEKHGDTGMTLLEIGEAAVRKSDNTAGNLLFEALGGP -AEFEEALREIGDDVTQSDRYETELNEFNPEDTRDTSTPKALATNLKKFAVGDLLPDEKRE -LFTDWLQGNATGDTLIRAGAPEGWIVGDKSGAGTYGTRNDIAVVWPPDREPIVIAIMSRH -DTEDADYDDALISEAAKVVFD-- ->[subseq from] carbapenem-hydrolyzing class A beta-lactamase n=1 Tax=Aeromonas salmonicida TaxID=645 RepID=UPI001024A3DA ---AFESQIRTLETEFDGYVGVHAVNTGTGKIL-QYRSDERFPLCSSFKGFLAAAILKKSQ -QEEGLLAENVRYIGREMEHHSPITKQYQSTGLSVSAMSAATVQYSDNGAANMLMERIEGP -KGLTTFMRGIGDNEFRLDRWELELNSAIPGDERDTSTPKAVAESLQKIALGSVLQQPQKK -IFQQWLIGNTTGDARIRAAVPKEWKVGDKTGTCGYGTANDYAIVWPDKSEPLVIAIYTKS -KEKHKKHSDKLISEVAGIVIK-- ->[subseq from] PSE family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio cholerae TaxID=666 RepID=UPI001158E21C --qSVEQEIKGIESSLSARIGVAILDTQNGESW-DYNGDQRFPLTSTFKTIACAKLLYDAE -HGKVNLNSTVEIKKADLVTYSPVLEKQVGKPITLSDACLATMTTSDNTAANIVIYAVGDP -KSITDFLRQLGDTETRLDRVEPELNEGKLGDLRDTTTPNAITSTLNQLLFGSTLSEASQK -KLESWMVNNQVTGNLLRSVLPVKWSIADRSGAGGFGARSITAIVWSEEKKPIIVSIYLDQ -TEDTMAERNDEIVKIGR------ ->[subseq from] Beta-lactamase n=2 Tax=Microbispora TaxID=2005 RepID=A0A5D0P9W9_9ACTN ---AVRKALRRLEVSFRGRIGAYAIDMATGITI-GYREGERFPLASTFKAFAAGAVLAGTT --EAELTRQVVRWTAGEVKPHSPQTGRHVADGMTLAALCRAAIVHSDNTAGDLLLKRIGGP -RGLTRYFRSLGDPVSRLDRWEPELNVWSPRERRDTTTPVSIARDLRALTTGGALDAADRS -RLVGWLRGNTTGDARIRAGLPPKWIVGDKTGTGGYGTANDIAVVWPADAAPIILAIYTNR -LTPGGSADDEVVARTATVLV--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EA103A --aQARDMLGDITAEIGGRLGVSVFDTGRGWRL-GIDPDTRYPLCSTFKLPLAAAILARAD -MSQLPLNRMIRYSEADLLDYAPAVRANLAAGMSVLELCEAAVVLSDNSAANLLLPQIGGP -AGLTRFFRAHGDRLSRLDRDEPTLNIFRREDPRDTTTPLAMTMLMERLLIGEALQPVSRG -RLIEWMVASQTGAKRLRAGLPKGWRTGDKTGTSGAGQYNDIAITWPPGGKPILIAVYIDA -PGLAAERADAAMARIGGLVGDVf ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N7F3P6_9PSEU ------EHLVALERKYDARLGVFALNTSTGASV-AHRADERFAFCSTFKGLAAAAVLHRNP ---MSHLDTLVRYAEGDLLKSGVVTSQHVATGMTIRQLCDAAIRFSDGTAGNLLLRDLGGP -QQLTDYLRGLGDTVTRMDRTEPAIVEATPGDPRDTATPRSLGTDYQKIVLGDALPEDKRA -LLRDLMERPATGAQRVRAGLPKDWRVADKTGTGDYGTLNDIALVWPPGKPPLLIAIMSSK -AAKDAKYDHQMLAEAASYA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B8ZI14_KLEOX ---AIHQKLTDXEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGDALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDY------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0010BDD638 --qATHKEFSQLEKKFDARVGVYAIDTGTNQTI-SYRSNERFAFASTYKALAAGVLLQQNS ---IDTLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRQMGDRITMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRN -ILTEWMKGNATGDKLIRAGVPTDWVVGDKSGAGSYGTRNDIAIVWP-------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Vibrio sp. SBT000027 TaxID=1803384 RepID=A0A3L7DQ87_9VIBR ------ESIEQIESRVSARIGVAVYDSTTEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodobacteraceae bacterium Alg231-04 TaxID=1922228 RepID=UPI000D5509A6 -----QKELQMIEARSGGRLGFAALDTQDGRRS-TWNSGDRFALNSTFKFRLAAAILMRVD -DGQETLTRRIPVPAKGLVEWSPLTRANAGHDMTVDQLCAAAVSFSDNTAANLLLDSLGGP -KGLTQLMRAAGDGMTRLDRTEPSLNGATTGDPRDTTTPDAMLAAMGDLLTGDLLQTASRQ -RLAGYLHNSTTGASRLRAGLPGNWTAGDKTGTGNNGAVSNIAILYPPGRAPVLVAAYFQD -SHRPQADLDALHAELGRLVS--- ->[subseq from] class A beta-lactamase n=1 Tax=Aureimonas leprariae TaxID=2615207 RepID=UPI001247820D ---ALAGTVAALEKRTGGRLGVSVVDTASGAAW-SHRGGERFPITSTFKAFACAHLLDLAD -KGEVDAKQRVRFEARDLEEYSPITKTRTGGEMSLLELCDAATATSDNSAGNFILAHTGGP -AALTGFMRRIGDGTTRLDRTEPALNDVGPGEVRDTTSPDAAAASLRKLMLGDALSEPSRR -QLETWLVADKVGGPLLRASLPEGWRIADRTGAGAYGSRSVIAVVWPKTRGPIVAAVYLTD -TTLDLDGRNAVVAEVGAALVK-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. L17-MgMaSL7 TaxID=1938893 RepID=A0A317MF96_9ACTN ---DFEAEFEALEEEFDARLGVYALDTGSGEEV-AFQEGERFAFASTFKALLAGVVLSGNS ---LEEMERVVTFDESVLVPHSPVVEENLESGMSLLELCDATVRFSDNAAANLLLEEIGGP -EGFGSALEETGDDVTNPVRWEPDLNEAVPGDERDTSTPEALAGSLEAFTLGEVLPEDRRE -VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGGGGHGTRNDIAVLWPEEGDPILLAVLSSR -DVEDAEYDDALVAEATEVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia liquefaciens TaxID=614 RepID=Q7X5K5_SERLI ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTHYPGQHGRDPAQAADQPASERPFAT -AAAAVDGGRRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium ulcerans str. Harvey TaxID=1299332 RepID=X8FCG8_MYCUL ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYS ---IAHLGTVITYNSADIRSTSPIIEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTPHAIAMDYQQVVLGDALLPEKRD -KLIDWLGRSTTGAKRIRAGFPADWRVIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDR -VGPEAPWCDPLVGDAAKCVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. WL18 TaxID=2603897 RepID=UPI0011C7AE39 ------PALAEIERRLGGRLGVSAG-TQERVLL-SHRADELFPMCSTFKALAVAAILARVD -AGSESLDRAVGFGPGILLSYAPVTRKVVEAGMTISDLCAAAIVWSDNSAANLLLTALGGP -EALTVWLRGTGDTRTRLDRDEPTLNTALPGDPRDTTSPEAMRQTLGRVLLGPVLSAASRG -QLEAWMVGCQTGAKRLRGGLPPDWIVGDKTGSGDNGTFNDVAILRPPGRAPVLACVYVTG -ATAPAAAVEAAYAEIGRLMA--- ->[subseq from] SCO family class A beta-lactamase n=1 Tax=Rhizobium sp. TH135 TaxID=2067451 RepID=A0A2N4Y0R5_9RHIZ ------AAAQRVETELGMRVGFAVIDTGSGEMR-SYRADERFAMASTFKTLACATALSA-- --GEAVLAKETKIRKADLRPHSPVTEKRVGTSLSTRSLCEITLRTSDNAAANAILKSIGGP -SELTAFLRRIGDGTTRLDRYEPELNEATPGDPRDTTTPQAMAETLQRLLLDGALEPEARD -QLEAWMAANAVADGLLRAELPVGWKIADRSGAGGHGTRGVVALLQRPVGAPLVVAIYMDG -RKHPLKTRDAAIASIGKAIFAEy ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura kijaniata TaxID=46161 RepID=UPI0009FE1E74 ---DLERTLRELETSYQGRVGAAAIDMSTGKAV-GYRAHESFALNSTFKAYACAAVLRKSD -SDPGLMDRLLHWKTGDLLPNSPETEEYTDTGMTPAQLCRATITKSDNLAGNLLLKQIGGP -AGMTGFFRSIGDPVSRLDRYETELNVWRPGEKRDTTSPAAAAGSLARLTVGDALDPRDRK -RLIGWLRGTVTGDTRIRAGLPKDWTVGDKTGTGGHGTANDVAVAWPPGAAPIVITVYTHR -NTNGVEHDDKVVASTATALAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI00062E6C5F --------VQY-FEDKGWSIGVTVLDTESGDMN-SVNGDNRFHFNSTIKALACANVLSKVD -ENRISLDDSISLKKSDIVTYSPVTEDYIGKKLTLRKACEAALTYSDNTAANYTISAGGGP -EGLTKFMRSIGDDVLRSDRYEPDLTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL -QLKKWMKDNKVANDLLRASLPQGWSIADRSGASDYGVRGIISMAWSKDHEPVIITMYVRK -SNTTMKERDQVIADLGKVIFEQy ->[subseq from] Beta-lactamase n=2 Tax=unclassified Mycobacterium TaxID=2642494 RepID=A0A5Q5BIW5_MYCSS --------LDALERANTAVVGVFAVNLDTGRTV-AHRAQESFAMCSTFKAYLAAHVLQLVG -RGERSLEQGLYVDAADILPNSPRTEPRVGGEMTLAELCQAILQVSDNAAANILLRDVGGP -PAVTAFARWIGDPRSRLDRYEIELNSAVPGDPRDTSTPEALGGGFRTLLTGDVLAPPQRR -LLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGTTNDVGIAYGPQGQRLLLAVMTRS -ATPDAENMRPLIGEVTAAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=A0A2S7UL81_VIBSP ------ESIEQIESRVSVRIGVAVYDSATKKAW-SYKGDERFPMMSTFKTLACANLLYDAE -NKGLDLDSKVNIKSEDLIVWSPVTKELVGKGISLRDACSATMTMSDNTAANIVLGGIDGP -NGLTQFLRSIRDSNTRLDHLEPELNHARPGDARDTTTPNSIVMTLNELMYGDTLSQASKA -TLKGWMMDNKVSDGMFRSILPSGWNIADRSGAGAYGSRAITAIVWSEHRAPLIISVSLTE -TEFTLQQRDKVINEVGQLIFDTy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhizobium TaxID=2613769 RepID=UPI0012604FD0 ---SIEEDIRLIETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD -QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP -AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDMLSPRSRG -LLTDWLVNGQDATQRLRKGVPAGWRIANKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH -APGSIESQEAVLADVARRVCD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8990 TaxID=2184552 RepID=UPI000F5ADBF1 ----AQAELAALEKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCTALLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTAFRLDRWEPELNQAAPGDERDTSTPVAMVDMLQRLLLGDTLREPPRA -QLTEWMTGGAT---GIAAGVPPGWRSAGKTGTGGYGTTTDVAVLWPPSRAPIVLAVSFTQ -PRADAAARADVVASAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Ralstonia insidiosa TaxID=190721 RepID=A0A191ZU84_9RALS ----LQQATQREEEALNARIGVAVIDKESGMTW-SYRGDEAFPINSTHKAYLCAALLEKVD -QKQLALSDRTTLSKRDLVAYSPITETLLPPQASNAQLCEAAVSHSDNTAANKVLEKIGGV -DGFNGFMRSIGDQKTRLDRKEPELNEGTPGDPRDTTTPVAAVRSLDQIFFSDHLSRSSKS -ELKTWMVNDKVAADLLRKSLPAGWDIADKTGAGGYGSRSIVAVVYPRGKKPLLVSIYITQ -TKATLGESNAAIARMGAILFK-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ITM-2016-00316 TaxID=2099695 RepID=A0A2S8LK54_9MYCO ---TLEEQIRELEARDNAFIGLYAVNLESGLSL-ENRADEAFALCSTFKTYAAARVLRGVA -DGEFTLEQPVFVKPEGILPNSPVTGERLGQEMTLAELSQAALQRSDNLAANLLLETIGGP -QAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGYRNLLAGDALPPAQRE -LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT -QSADAEGLRPLIGEVAALVL--- ->[subseq from] Beta-lactamase 1 n=1 Tax=Streptomyces cacaoi TaxID=1898 RepID=BLA1_STRCI ---AHEKEFRALEKKFDAHPGVYAIDTRDGQEI-THRADERFAYGSTFKALQAGAILAQVL -AEADGMDKVVHYGQDAILPNSPVTEKHVADGMSLRELCDAVVAYSDNTAANLLFDQLGGR -RGSTRVLKQLGDHTTSMDRYEQELGSAVPGDPRDTSTPRAFAEDLRAFAVEDALAPNDRE -QLNDWMSGSRTGDALIRAGVPKDWKVEDKSGQVKYGTRNDIAVVRPPGRAPIVVSVMSHG -DTQDAEPHDELVAEAGLVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Listeria rocourtiae TaxID=647910 RepID=A0A4R6ZDZ9_9LIST ---DTTTQLKNLEKKYQATLGVYAIDSGSGETF-AHNGNQRFAFASTVKALLGGVLLKNLS ---WDELNQIIKYTKDDLVSYSPITEKHVDTGMSLKDIIAAAIQYSDNTAANLMFKQFGGP -KGFESQLRELGDKVTDSSRLEPDLTTAIPGDIRDTSTPKAIAETFKKLLLDRKIAPDKLK -FYNEILTGNATGEELIRAGVPSNVKVGDKSGAASFGTRNDIAVLYPPHRAPIILVVFSNK -TNEDDEYDNALIADAARVMSN-- ->[subseq from] class A beta-lactamase n=1 Tax=Acaricomes phytoseiuli TaxID=291968 RepID=UPI00036070E3 --qELTSLLNRYESDSDLRIGLCAI-VNGEARL-SHRAEEVFPMCSTFKPIAVGAMLAQHA -EDTDYLRQAIRIAQNAVVDYSPITEKHAGATMTLAEICEAALRYSDNTAGNLILEQIGGP -AGVTAFANSLGYRNTRLDRWETELNEALPGDPRDTSTPADLCGIFDALLVGDGLAPAARD -VLRTWMRGNTTSAKRFGAALPAGARLADKTGSGSYGTAHDVGAVFRADAPPVILAVLTRT -QRQDAQSNDAAIAQTARVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora sp. E2A TaxID=2665642 RepID=A0A5Q3QHN1_9PSEU --------FPELEQRYGARLGVWARNAVTGRTV-HHRPHERFAMTSTFKPYAAAALLREHG -LAGDYFRHRVFFRREDLVVHSPICEQAVDTGMTVLELCDAAITYSDNTAGNLLLTELGGP -AAIAPFARTLGDPATRLDRWEPELNEAERGDPRDTTTPAAIGTGYGRLVLADGLPRPERD -RLTAWLLANTTGDTSIRAGVPPTWVTGDKTGGGSYATNNDVAVTWTDLDQPIIIAVLSDK -PIRDAEPDDALIADAAKRVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Mycolicibacterium thermoresistibile TaxID=1797 RepID=G7CD35_MYCT3 ---AIHQRLTGLENDHDQLIGLYAVDLGSGRTI-AHREHESFAMCSTFKTYLAAATLQRVQ -QGELQLDQRIFVPPAAIVTHSPRSEAAAGGHLTVAELCAAILQVSDNGAANTLLQTLGGP -PAVTEFARSIGDERSRLDRWEVALNSAVPGDPRDTSTPRALGEGYRTLLEGDVLAPPYRE -QLVEWMRTNET--SAMRPGLPPGWVSADKTGSGDYGTTNDVGLLYGPQGQRVVLAILTRS -ASPDAQNPRPLIGEITAAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium psychrotolerans TaxID=216929 RepID=UPI00138D19EE ------DRIDALRRRHNAEIGLYATDLESGREI-AVRDGDSYALCSTFKAYASAAILQRAQ -QGRLGLTGTVRVDRADIQPHSPVTELRVGTTMTLAELCQAALQQSDNAAGNLLLRTLGGP -PAITEFARGAGDDRSRLDRWETALNSAVPGDPRDTGTPRALGTGFRAVLTGDVLDPAHRQ -QLEDWMRANET--SSMRAGLPAGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRA -AGADAPNLRPLIGEIASVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. GA-1999 TaxID=1772275 RepID=A0A117JCY0_9MYCO -----DARIGEFERQHNALIGVFAVNLDTGRAI-AHRAQEPFAMCSTFKGYAAARILQKAE -RGELALSDRVAVEQSDIVPNSPVTQTRVGQTMTLAELCEAALQRSDNAAGNLLLRAIGGP -PAITDFARSIGDQRSRLDRWEVELNAAVPGDPRDTTTPEAIGGGYRSMLTGAVLAEPQRR -LLEDWMRANQT--SSVRPALAPGWTTADKTGSGDYGSTNDVGVAFGPDGRRLLLAVMTRS -AGPNAPNMRPLIGELAALLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Comamonas sp. B-9 TaxID=1055192 RepID=UPI0003959AE6 ---ALHKALTLIEAQSGGRLGVYAFDAETGGEA-GYRSDERFAMCSTFKTLLAAHVLYLGQ -TGALDLGQQVRVTSADMVPYAPVTEKYQDQPISLLELCEAIVVVSDNVAANLLLRASGGP -EALTAWLRTLGDKATRLDRPEPLLNTAEPGDPRDTTTPRAMQATLQALLLGDVLKGYGRA -MLQQWLTDSRTGDQRVRAGLPSEWRVGGKTGAGAHSTANDCLIAWPNAAEGLIITAFLTG -GERTTAQSDAVMAKVGAAIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium chlorophenolicum TaxID=37916 RepID=A0A0J6Z151_9MYCO ----VTDRIDALRRRHNAEIGLYAVDLDSGREI-AVGDGDTYALCSTFKAYASAAILQRAQ -QGRLSLTDAVPVERADIQPHSPVTEPRVGTTMTLAELCQAALQQSDNAAGNLLLRTLGGP -PAITEFARSVGDDRSRLDRWETALNSAVPGDPRDTSTPRALGTGFRTVLAGDALDGAHRQ -QLDTWMRANAT--SSMRAGLPAGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRA -VGPEAPNMRELIGEIASVVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3B38F6 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDAKADDALISGTAKAAAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Clavibacter TaxID=1573 RepID=A0A067LZ21_9MICO ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAATLLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDAKADDALISGAAKAAAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A2S3XAD2_PSEPU -------TALRLENALDARIGYAIHDTGTGLGW-EHRADERFPMASTVKLLVCSALLRQGQ ----VRMKKAWQIQQESILPHSPVTQNLVGKQVAASDLCAFTLKTSDNAAANGVLEVLGGP -AAVNAFLQEIGDQTTRSDRNEPSLNEGQPGDLRDTTTPKAMAGTMKSLVLGSALKDEPRR -QLTEWLMSNQVGGPLLRAGIPGDWRIADKTGSGGFGTRGVVAVMWPPQRAPIVAAIYLTE -TTASMDERNAAIAEIGRAMVK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=W7ZR08_9BACI --eTMEQGFSQLEDRYHAILGVYALHTETGETI-ASNEEDRFAYASTHKALSVGVLLQQHS ---LEELDKRVHYNEKDLVTYSPITEQHVETGMTLKELSDASIRFSDNPAANFIFNEIGGP -EGFKHALQDMGDQVTEPKRWETELNHWAPGEVSDTSTAKALVETLHGVALGDELDEEKQD -LFTDWLVHNTTGDTLIRAGVPKGWQAGDKTGSAVYGTRNDIGIIWPPDHAPVVLAVLSHT -DEEDGEVDDHLIADATKEV---- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI001244BF78 -------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -NGLTEFLRFMGDRKTRLDHIEPYLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE -TELTIPERDTVINEIGELVFDEy ->[subseq from] Beta-lactamase n=1 Tax=Leisingera sp. ANG-M1 TaxID=1577895 RepID=A0A0C1GM57_9RHOB --eALAETVSQVEQRLGGRVGLSIKEVDGPTSW-SHREDERFLMNSTVKTPVCGAVLAQRD -AGALTLSDALPVREADLQSYAPVTKSRVGEEMTIGALCLAALDMSDNTATNILIDHLGGP -QAVTQFFLSIGDPISRLDRPEPDLNTFAPGDPRDTTTPAAMAATLEKLLLGHALTAASRD -LLTDWMSHGGVTGNLLRADAPAGWQVFDKSGSGSH-TRNIIAMVTTDKGAPWITTIFLSD -VDADFDTRNAALQELGSAVM--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000CE92C40 ---AADAAFTALEERFDARLGVHLVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADVLSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEAFGGP -AELDAALTALGDETTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLQATRTGDTLVRAELPTEWTVGDKSGSGAYASRGDVAVVWRPDAAPLVIAIHSSR -DAQDAEPDDALISGAARAAVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Leisingera sp. NJS204 TaxID=2508307 RepID=A0A481PGG3_9RHOB --eALAETVSQVEQRLGGRVGLSLEEVGGQTSW-SHREDERFLMNSTVKAPICGAVLAQRD -AGALALSDALPVRAADLQSYAPVTKTRVGKDMTIEALCFAAIDMSDNTATNILIDRLGGP -QAVTRFFRGIGDPISRLDRREPGLNTFVPGDPRDTTTPAAMAVTLEKLLLGSALSPVSRD -QLADWMSHGGVTGNLLRADASADWQVLDKSGSGSH-TRNIIAMVTPGKGAPWIITIFLSD -ADADFDTRNAALQKLGSAVM--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. UNC267MFSha1.1M11 TaxID=1502745 RepID=A0A1G4W306_9MYCO ----LDQRIGALERRHNAVVGLSAVNLNSPGAV-AHRADQMFAMCSTFKAYAAGRVLEQVG -RGELALEATEFVDPSAVVANSPVTGPRAGSQMTLAELCQAALQRSDNTAANLLLRRLGGP -PAITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPAALAGGYRALLTGDVLAPPQRL -LLEQWMRANQT--SSMRAGLPAGWSTADKTGSGDYGSTNDVGVAFGPEGQRVLLAIMTRS -AVDDADALRPLIGELTTL----- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D90E6A ---SLTQNIEAIELSSGGYIGVSVLNTETNKMW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSVLPNDWSIADRSGAGGFGSRGITAAIWNDNHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429AZP1_9ACTN ---DVKKRLRALENSYQGRIGAYAIDTGTGKTI-SYRGGELFPSASTFKAVLCGAILAKAR -TDPGLLNRTLRWTAKELVTNSPITEENLKNGMTVDRLCHAAVTASDNTAANLLLKQIGGP -AGLTRYYRSLGDPIGRLDRWEPELNDWKPDEKRDTIKPAFMARNLQKLTLGSTLVPEDRQ -RLNDWLRASVTGTERIRAGLPKNWTVGDKTGGGSYAPGNDIAVAWPPSGAPLIIAVYTNR -NDPTATMDNSVIAKAATLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=Q6T3Q5_ALIFS ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium moriokaense TaxID=39691 RepID=A0A318HLU4_9MYCO ----IDERIAAIERRRNAYVGLFAADLEAGRSI-SHRGQQAFAMCSTFKGYASARVLQMVE -QGELTLDHEVFVDPAEIVANSPRTQPRAGGGMTLDELCQAALQVSDNTAGNLLLKTIGGP -PAITAFARSIGDPSSRLDRWETALNSAVPGDPRDTSTPEALGGGYRHLLTGDALAPPQRQ -QLEDWMRANET--SSMRAGLPPGWTTADKTGSGDYGSTNDVGVAFDPAGRRILLAMMTRS -QVNDAPNLRLLIAELTSLVV--- ->[subseq from] Beta-lactamase n=1 Tax=Angustibacter sp. Root456 TaxID=1736539 RepID=A0A0Q7JIM7_9ACTN ---QLEAQFTALERRRGGRLGVYALDTGSDRSL-SHRGDERFAMASTVKVLAVAALLDRLS ---AADLGRRLRWTSGDLVAHSPVTERFVDRGMTIRQLIDASLTRSDNTAANLLFEQVGGP -TTVGDFVAAAGDDITSVDRREPALNDWAPGETRDTSTPRALGGTLATLVRGDVLEPADRL -VLERAMRDSVTGAGLVRAGVPDGFVVEDKSGTARYGVRNDVAIVRPPGGAPWILAVMTSH -ETADAEPDDELVAAATRIVVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C3448 ----AEQSYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. L17-MgMaSL7 TaxID=1938893 RepID=UPI000D71123C ---DFEAEFEALEEEFDARLGVYALDTGSGEEV-AFQEGERFAFASTFKALLAGVVLSGNS ---LEEMERVVTFDESVLVPHSPVVEENLESGMSLLELCDATVRFSDNAAANLLLEEIGGP -EGFGSALEETGDDVTNPVRWEPDLNEAVPGDERDTSTPEALAGSLEAFTLGEVLPEDRRE -VLVDLLVRNTTGDDLIRAGVPEGWVVGDKTGGGGHGTRNDIAVLWPEEGDPILLAVLSSR -DVEDAEYDDALVAEATEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI000CE93D5A ----LEQRVQYF-EDKGWSIGVTVLDTESGNIN-SVNGDKRFHFNSTIKALACANILSKVD -KNKISLDNSIYLKKSDIVTYSPVTEDYVGKKLTLRKACKASLTYSDNTAANYTISAGGGP -EGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMASSLNKLLLENVLSEESKL -QLKQWMKGNKVANDLLRASLPQGWAIADRSGASDYGVRGIISMAWSKDHEPLIITMYVRK -SNTTMKERDQVIAEIGKVIFEQy ->[subseq from] Uncharacterized protein n=1 Tax=Luteipulveratus mongoliensis TaxID=571913 RepID=A0A0K1JPL3_9MICO -----AASLQPLESRHGVRLGVYAIDTGTKREV-AYRADERFAYASTFKALAAAMVVRKVG ---LPGLGRRVPIAQSDIVDNSPVTGKHVGGDMALREIIDAALRFSDNTAGNKLLAELGGP -TGFGRTLQTLGDQVTRPTRWETDLNSGAPGDLRDTSTPRQLAVDLRAVLLDSALPRPEQA -LLRDVMWRNTTGDKTIRAGVPHGWPVADKTGSASYGRRNDIAVIWPPNRSPVVLSVLTAR -DKADAPTVDAAVADATKAVLR-- ->[subseq from] class A beta-lactamase n=1 Tax=Desulfovibrio desulfuricans TaxID=876 RepID=UPI0003B781BD ---DLPKMLAELEASSGGRLGVAASVSNGGNVL-SYRGDERFPMCSTFKVLAAAAVLRDKP ----DILEQRIHFAKNDIQPWSPVSEKHLEDGMTVSELCAAMLQHSDNTAANLVLAQLGGP -AGLTTIARSFGDTTFRLDRWEVELNTAIPGDARDTTTPIAMCRTLNGLLCGNQLKAPAQK -QLTDWMLGCATGAGRIPAGAPQGWRPAHKSGSGENGTANDVGVLLPPKNKPRTVALYLTG -SRLTGSGNDKILAQATRLVC--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI0004292E84 ----LDQRIAALERRHGARIGLSAVDLDGPGAV-SHRADESFAMCSTFKAYAAGRILQGVE -RGEFPLDATEYVDPAAVVANSPRTGPRAGTELTLADLCQAALQVSDNTAANLLLKRLGGP -PAITAFARSIGDERSRLDRWETELNSAVPGDPRDTSTPAALAGGYRALLTGDALAPPQRS -LLEQWMRANET--SSMRAGLPQGWTTADKTGSGDYGSTNDVGVAYGPDGRRVLLAIMTRS -AADDAAGLRPLIGELA------- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium sp. Root265 TaxID=1736504 RepID=A0A0Q8ZV29_9MYCO ---TLEEQIRELEARYNAFVGLYAVNLQSGFAV-ENRADEAFALCSTFKTYAAARVLRGVA -DGELTLEQQVFVKPEGLLPNSPVTGERLGQEMTLAELSQAALQRSDNLAANLLLETIGGP -QEITAFARSVGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGFRNLLAGDALPPAQRE -ILDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT -QSADAEGLRPLVGEVTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA2124 ---SLTQNIEAIELSSGGYIGVSVLNTETNKMW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTTITKEQIMPWSPITEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSKTLNVLLFGNTLNPQDKQ -TLKSWMMNNKVSDPLLRSTLPSNWSIADRSGAGGFGSRGITAAIWNDNHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=UPI0010721843 --kTIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQTIMINQEDLVDYSPITEKYVGVGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEAIPGDRRDTSTPKAIALDLKKLTAEKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTEVLVGDKSGAASYGTRNDIAVLYPPNRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVGDYf ->[subseq from] Beta-lactamase n=1 Tax=Halomonas halophila TaxID=29573 RepID=A0A510ZAL5_9GAMM -------------------MGVALMNVATGAVA-SHRGDERFLFNSTGKFFIAAAVLARVD -EGSETLDRRVVIEEGDLGGWTPITEKRLGEPLTLAELCQAAVAWSDNAAANALIESVGGP -EAVTAFLREIGDDTTRLDRLEPELNTDHAGDERDTTTPLAMMTTLRTLLLGDVLSPSLRH -QLASWMIEGKTGDARLRAGMPSSWLVGEKTGTNGVGNANDIGIAWPGDRGAVIAVAYTRM -PSATAEQRDETIAAVGRLAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudooceanicola sp. CAU 1508 TaxID=2599291 RepID=UPI00131C2815 --eALSDTVEQVEQTLGARVGLALVDTGSGRSW-FHRGDERFLMNSTVKVPVCGAVLALDD -AGVLDLSESLPVVQEEILSYAPVTKTRVGQQMTLAELCLAAIDISDNTAANMLIDRVGGP -QAVTAFFRAAGDQASRLDRREPELNSFRAGNPQDTTTPAAMSGTLRALLFGEVLSPAARE -QLAEWMSQGGVTRNLLRADAPASWQILDKSGAGSH-TRNIIAAITPDGGDPWIVTIFVSD -VDADFETRNAALRRIGSAAM--- ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. SA39 TaxID=1263625 RepID=UPI0005F9E411 ------ARFTALEERFDVVVGVYAIDTGSGRTV-EYRPDDRFGFASTIKAIAAGLVFSTTT ---DEQLDAPIAVTSDDLVPYSPVIEQRVGGTVSLLEAADAAVRFSDNAAANLLFRHLGGP -EAMETMLRDVGDTTTNADRIEPELNDVSPGDDRDTSTPRAMATTLADLALGDALDVDDEA -RLIDLLQRNTTGDALIRAAAPEGWTIGDKTGSAAFGTRNDIAIAWPPDREPIVIAILTRG -HDVDAEPIDEVLAEAAALVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter liquefaciens TaxID=89584 RepID=A0A370G4W1_GLULI -----EGAIAAYERATGGRVGVFARNIASGKSF-AWRQDERFVMCSTFKASLAACVLARVD -RGDADLDEVIAFTAADIGEYAPVAKENLGRGMSVREMCAGAVEFSDNVCANKLLIRIGGP -AALTRFWRAMGDDVTRLDDIEPFLNRTPMGGVRNTTTPMAMAGVVRRLVLGDVLSEGSRA -TLKTWMVNCQTGKNRLRAGLPGQWVVGDKTGNNGKDAAGDIAIAWPGVGGPIVMAVYTRG -GTPNDAQFAALFAGIGRHVA--- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella sp. RIT-PI-d TaxID=1681196 RepID=A0A0L0AXC7_9ENTR ---ALTGYLQQQESQLNARIGMAVVDAQGTPGF-GWRENERFPLTSTFKVLTCAALLDQLH -KKHGSLEERVSLQPTELLDYSPIAKNYLPPEISLRKLCSAAVSYSDNTAANRLLTWLGGP -AAVTQFMRSLDDNVTRLDRTEPTLNMATPGDVRDTTTPHHIVRSLRLLLASDVLTQTDRA -TLDNWMREDNVADALLRSTLPEGWAIADKTGAGGYGSRAIIAAVYPPQKPPFYVAIYITQ -TTASMKTADAVIAEIGRRLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium lusitanum TaxID=293958 RepID=UPI00119AE6BF ---SIEEDIRLIETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD -QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP -AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDTLSPRSRG -LLTDWLVNGQDATQRLRKGVPAGWRIANKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH -APGSIESQEAVLADVARRVCD-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA796F ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITQEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium cosmeticum TaxID=258533 RepID=W9AY91_9MYCO ----LDQRIAALERRHGAKIGLSAVDLDGPGAV-SHRADESFAMCSTFKAYAAGRILRGVE -RGEFPLDATEYVDPAAVVANSPRTGPRAGTEMTLADLCQAALQVSDNTAANLLLKRLGGP -PAITAFARSIGDERSRLDRWETELNSAVPGDPRDTSTPAALAGGYRALLTGDALAPPQRS -LLEQWMRANET--SSMRAGLPQGWTTADKTGSGDYGSTNDVGVAYGPDGRRVLLAIMTRS -AADDPKA---------------- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. KC712 TaxID=1848329 RepID=A0A4R4WLA6_9ACTN -----RKELRKMEVAVKGRIGAYALDTATGKTV-TYRAGERFPMLSTFKAPLCAAVLQKAR -AEPGLMNKLITWTGADMKPNSPVTEKHVKDGLTVSQLCEAVVTRSDGTASNLLLKQIGGP -KGLTKYFRTLKDPTSRMDRWHPELNDWTPKDKRDTTTPAAIGRDLRVLTVGRALHAKDRR -QLLAWLLANKTGGERIRAGLPKTWTVADKTGTNSFGGGNDIAVIWPKKGAPLIMSIYTNR -TK-GLPTDNTTIAKTATVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Virgibacillus dokdonensis TaxID=302167 RepID=UPI000989AD94 -----ESEFRLLEKEYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT ---LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP -NGFKKALGDIGDNVTNPERMEPELNLVNPGEIKDTSTPKALATSLKAFTIGNVLPKEKQD -LLVDWLKRNTTGNHLIRAGSPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK -EEKNAKADDKLIAEATKKVI--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1554424.7 TaxID=1834082 RepID=A0A1A0LEX2_9MYCO -----YKRLADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG -ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP -AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSEVDTSTPKDMATSVQALTVGDALAPPQRA -QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ -NRREANAREDIVASATDAILGRf ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella sp. RIT-PI-d TaxID=1681196 RepID=UPI000675EC46 ---ALTGYLQQQESQLNARIGMAVVDAQGTPGF-GWRENERFPLTSTFKVLTCAALLDQLH -KKHGSLEERVSLQPTELLDYSPIAKNYLPPEISLRKLCSAAVSYSDNTAANRLLTWLGGP -AAVTQFMRSLDDNVTRLDRTEPTLNMATPGDVRDTTTPHHIVRSLRLLLASDVLTQTDRA -TLDNWMREDNVADALLRSTLPEGWAIADKTGAGGYGSRAIIAAVYPPQKPPFYVAIYITQ -TTASMKTADAVIAEIGRRLF--- ->[subseq from] Beta-lactamase n=2 Tax=Agrobacterium sp. RAC06 TaxID=1842536 RepID=A0A1B3P1E8_9RHIZ ------AAAKRVEQKLGMRVGLSVIDTGSGAVV-AYRDDERFAMASTFKSLACAAALSGGD ----AVLEQTTRITKADLRPHSPVTETRVGTSLSTRELCEITLRTSDNAAANAILKVLGGP -AEVTGFLRGIGDATTRLDRYEPEVNKAKPGDPRDTTTPQAMAQTLHRLLLDGALPPPARD -QLEAWMAANAVAGGLLQAKLPKGWTIADRGGAGGHGTRGVVALLRPPQGAPLVIAIYMDG -RKHPLMTRDAAIAEIGEAVFEEf ->[subseq from] Beta-lactamase n=1 Tax=Paracoccus sp. 3058 TaxID=2561921 RepID=A0A4Z1BZ91_9RHOB ---DLVETIDSLEDRLNARIGVAILDTRTGQFW-SHRADERFLMNSTVKVPLCAAVLSRAD ----IALTEDLPVRMSDILKYAPVTEQHVGGTMTIDDLCEATIDQSDNTAANVLFHRLGGP -KELTAFLRSIGDGTTRSDRIEPELNTFSEGDERDTTTPAAMVRTLEVLLVGNGLSASAKE -QLADWMRPGGVTGALLRPSAPAGWDVADKSGSGSN-TRNLIAMLTPPDEAPIFFSLSISD -TDADFATRNAALTELSAAVMR-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI000494E974 -------SIAKIESRISARIGVAVYDSATDQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLDSKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -SGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRLILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELAIPERDTVINEIGELVFDGy ->[subseq from] class A beta-lactamase n=1 Tax=Luteipulveratus mongoliensis TaxID=571913 RepID=UPI000696059D -----AASLQPLESRHGVRLGVYAIDTGTKREV-AYRADERFAYASTFKALAAAMVVRKVG ---LPGLGRRVPIAQSDIVDNSPVTGKHVGGDMALREIIDAALRFSDNTAGNKLLAELGGP -TGFGRTLQTLGDQVTRPTRWETDLNSGAPGDLRDTSTPRQLAVDLRAVLLDSALPRPEQA -LLRDVMWRNTTGDKTIRAGVPHGWPVADKTGSASYGRRNDIAVIWPPNRSPVVLSVLTAR -DKADAPTVDAAVADATKAVLR-- ->[subseq from] Beta-lactamase n=2 Tax=Gluconobacter frateurii TaxID=38308 RepID=A0A0K8N3A8_9PROT ----------SYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD -QGKESLETVVPYTASDLRDYAPVAKANVAAGLSVRAMCQAAVEWSDNACANLLLARVGGP -ATLTQFWRSLGDHETRLDDWEPVLNRTPPGGLRNTTTPAAMAGILQQLVFGHALSGASCS -LLTGWMKNCQTGKGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG -GHPDEKQFFEVFSEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter halimionae TaxID=1926630 RepID=UPI00135E70E1 ----ALEQIEAIEERLGGRLGVSLVD-GSGQALlTHRGDERFAMCSTFKAPLAAAIMLEVE -QGRLSLEQQIEFTQADVVPHAPMIERALEGQRPVDWLVLAAMRASDNSAANILLDRIGGP -EGMTQFYRNHGDGVTRLDRREPELNENSPGDPRDTTSPLAMAQLIRHVMLGDAVHPGLRA -ILVRHMIRTDTGMSRIRAGLPEGWVVGDKTGTCGS-AYNDVAVFWAERDRPYVLSIYYDR -PEAESEEAQAAMAQVGALAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sediminis TaxID=1286180 RepID=UPI00138B9813 ----VEDRIGALERTYGAYVGVYAENLDTQTSV-AHRADDPFAMCSTFKAYAAGRVLQKAA -AGELNLTDAVTIEQSDILPNSPITETRVGRNMTIEELCVAAVERSDNAAANWLLRIIGGP -SRITDFARTLGDDRTRLDRWEPELNAAVPGDPRDTSTPRAIGSGFRSMLTGEALAEPERR -TLDRWMRGNQT--SSMRPGLGPGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLSFMTRT -RSPDAEAMRPLIGELATLIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Reyranella soli TaxID=1230389 RepID=UPI0011BF9B23 ---DATSRLAELERRNGGRLGVAAIDTASGRRV-GHRAEELFPLCSTFKFLAAAFVLARVD -RGEEKLDRRVFFTDRDLVTYSPVTKQHVGLGMTMAEICEAAVTLSDNTAGNLMLASFGGP -AGLTTYARSLGDRTTRLDRIETELNEAKPGDPRDTTTPVAMLDTMQRLLIGDALSASSRD -QLIGWLLASKTGARRLRAGIPADWKVGDKTG----------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium frederiksbergense TaxID=117567 RepID=UPI001436FBDA ---TLEEQIRELEARDNAFIGLYAVNLQSGFSL-ENRADEAFALCSTFKTYAAARVLRGVA -DGEFTLEQPVFVNPDGILPNSPVTGERLGQEMTLAELSQAALQRSDNLAANLLLETIGGP -QAITAFARSIGDDRTRLDRWEIELNSAIPGDPRDTTTPRALAAGYRNLLAGDALPPAQRE -LLDGWMRANQT--SSMRAGLPPGWTTADKTGSGDYATTNDSGVAYGPDGARVLLTIMTRT -QSADAEGLRPLIGEVAALVL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-340-1 TaxID=2022505 RepID=A0A260H341_9NOCA ---SAEQNYVDLEARDTARLGVSAVDLGSGSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGALQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTPASRD -RLLAWMTDTQTSDGRFRAGIPEQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNSLVADATRAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. ERR1071 TaxID=2572677 RepID=UPI00119D4EAB ---AIEENIRAIETKSGGKLGVAVLDTATDRVV-GHRLDERFALCSTFKALAVAFVLARVD -QGKEHLDRKVVFSKQDLVLPYKATKPHLGPEMTIGELCKAAAIYSDSTAANLLLASFGGP -AALTAYLRSIGDSVTRVDNVEPKLNIVKPGELHDTTSPRAMAGTMKRLILGDVLSPRSRG -LLTDWLVGGQDATQRLRKGVPTDWRIANKPGTWEGISTNDVGVIWPPHRPPVIVAAYLGH -APGSIKSQEAVLADVARCVCD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces katrae TaxID=68223 RepID=A0A0F4JH29_9ACTN -----VRRLREMEREHGARIGVYARNLVTGRTV-ANRAEETFPVCSVFKPLAAAAVLRDLD -RDGEFLARRVHYTAAEVEAWAPVTKDHVADGMTIEALCAAAVSQSDNLAGNLLLRELGGP -TGITRFARSLGDRVTRLDRWEPTLNSAEPWRVEDTTSPRAIGETYVRLLLGNALARKDRD -RITGWLLANTTNTQRFKAGLP-GWTLADKTGGGNYGVANDVGVVWSPAGVPVVMAVLTTR -PEAPGPNDSKLVADTARLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia fusca TaxID=941183 RepID=UPI000A06E554 ---DLSNTLMTLQAKYNVLFGIAAVDTRGGRTF-EWNADDRFALCSTFKVYAVAAILRLAE -RKELDLNDKVPITRQDIVMSSPVVSDHVGELMSYYELSRAALVRSDNTAANLLLRRLGGP -GAVTRFARSVDDSQTRLDRWEPELNEARAGDPRDTGTASALAAGYRKLILGDGLSTEYRR -MLTSWMRSSVTSRQRLRAGLPVGWVAADKTGSGAYGTANDAGVVWSPTGSSLVLVVFSRS -TTPMAAGADAAVADATAAVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium grossiae TaxID=1552759 RepID=A0A1E8Q4S2_9MYCO ----IEERIAELERRYGAFAGVFAQNLVTGATV-AHRADDPSAMCSTFKAYAAARVLQKSA -ARELNLTDAVTIEASDIVPNSPVTETRVGANMTIAELCAAALQRSDNAAGNWLLRIIGGP -SRITDFARSIGDDRTRLDRWEIELNAAVPGDPRDTSTPRALGSGFRDLLTGTVLGASERG -RLEEWMRANQT--SSMRAGLPPGWASADKTGSGDYGVTNDVGVVYGPDGQRLLLAFLTRA -QAPDAESVRPMIGDLAALLVR-- ->[subseq from] Class A beta-lactamase n=2 Tax=Microbacterium TaxID=33882 RepID=A0A6D1IHK9_9MICO ----LTLELAALEAAHGGRLGVFAVDVASGGFV-AYREDERFAYASAIKALLVAAVLRKIP -----DLERVVVFSEEELVFQSPVTQQHAGTGLTIRRLCEAALRDSDNTAANLLLEELGGP -AGFEIALREMGDHTTMPARFETDLNSATPGDDRDTSTPRALARSLRSVIAEDLLPDGRAT -LLIEWMSGNATGDTLIRSGAPPDWLVADKSGTGGYGTRNDLAVVWPPGAGPIFIAVMTTS -ESKEAAPADSLVARAAALAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium sp. 7209-2 TaxID=1850373 RepID=A0A4S8NDI8_9RHIZ -----TAAAQAVETRLGMRVGFAVIDTGGGKTL-TYRADERFAMASTFKALACASALSGG- ---QAVLDKETRITTADLRPHSPVTEKRVGTRLPTRELCEITLRTSDNAAANAVLAAIGGP -PALTTFLKGIGDGTTRLDRYEPELNQATPGDPRDTTTPKAMAETLRHLLLDGALEPGARE -QLEAWMAANAVAGGLLRAELPAGWTIADRSGAGGHGTRGVIALLRPPEGPPLVVAIYMDG -RKHPLKVRDAAIAEIGKAIFAEy ->[subseq from] Beta-lactamase n=1 Tax=Segniliparus rugosus ATCC BAA-974 TaxID=679197 RepID=E5XRK8_9ACTN ----FADAVTALERGHEAEVGVFVLDTGSGKTL-EHRADQRFMMCSTFKALLAGAVLRKAQ -DEPGLLDRSIPVPAEAAAGYAPFGNSRLGKSATLAELCEASIQISDNIAANLLIDFLGGP -PAVTSFFRSLDDTVTRLDRHEEAMSDGEAKDLLDTTTPRAIAKTLHKLALGEALAKPQRQ -QLVDWMLGSVTGTECIRAGLPSEWKVADKTGTGARGERHDIAIVWPTGGAPLAVAILTRV -QN-KAERNDQLLADVASAA---- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. YM53 TaxID=1572659 RepID=A0A4R0JNJ3_9ACTN -----KEQLEQVLGPVHAQAWVHAVDLATGKET-GYGEDTPVVLASVFKIPVLVELFRRFG -DSRLDPATRMDVPVDGRSAGPTGLSVMADPILSLCDLAYWMMSVSDNAATDILVNLL-GT -ESINATVRELGLTATRVDGTCDDIYQIDPDRTLQASTPRDITRLLAAIWNDEAAPPEQCA -EMRRILAGQAW-PHRLRSAFTTGTIVSAKTGTLRF-WRNEAGVVRTPDGRQYAVASFVRT -DDPDLPAVDAAVGSVARILVD-- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. YM53 TaxID=1572659 RepID=A0A4R0JNJ3_9ACTN -----PDEIRAYAGELGAEIWLHARDLATGRTV-GVDAETPVVTASVLKVPVALELARQSV -AGEVDLTERITVPTEGLVASPYGLAMHRDPTISYNDLALLMMVISDNVATDLVIDRV-GK -DRVAALLAELGLPGTAVPQNCAEILAALDPAGTCRTTPDEITSLLAGIWRDEAADPEACA -LVRGWMGNQVW-PHRLSSGFPDDITVSGKTGTLPL-VRNEVGVVEFPDGGRYAVGVFTRA -ADPNAPQFDGLIGWAAA------ ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00080D949D ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLSEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=UPI000940D7BA ----AESPLADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGLLAAQVLARVD -SGKDSLERFVRYTEKDLIFTSPVTKANVAQGMSVGALCQAIVEVSDNTAAILLMRSVGGP -AALTQFVRSLGDTVTRSDRYEPESNQY--SGVLDTTSPRAITQAVSRILLGDVLSPPSRA -QLESWMVACKPGLNRLRASLPADWRAADRPGTSVEEETNDYAVVRPPGRAPLLVAAYYDA -PGVSMDAREAVLREAGAVFV--- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A1B9PCI2_ALIFS ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTTITKEQIMPWSPVTEPLVDHIITTKKACEATMLMSDNTAANIVLNEIGGP -RSLTQFLRAIGDDKTRLDRIEPKLNEAKNGDKRDTTTPVAMSETLNTLLFGNTLNPQDKQ -TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. CPCC 204705 TaxID=2306636 RepID=UPI0010A8EFBD ---DLTAALADVEARHGVRLGLHAVDTAQGRTT-SHRADERFAFCSTFKPLAAAAVLASRT ---VAGIDQPVPVAADDLVDFSPVTADRVGGTMTWRELGDAAMRFSDNTAGNLLLRGAGGP -EGLTAWLRTVGDDVTRSDRWEPELNAFVPGDDRDTSTPRALAGTYRTLVVGDVLGAPERD -VLTDWLVRNTTGDALVRAAARPRWTVGDKTGAGAYATRNDVAVVWPGEGAPVVLAVCTDR -PSPDAERTDAPVAEAARVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardioides sp. Soil805 TaxID=1736416 RepID=A0A0Q9SY04_9ACTN ---AFAGRLRHLEREKDAVVGVYAFATGTGEDL-AYRADERFAFASTGKALAAAVVLDQLS ---SRDLSRRLYWTEADLVPYSPVTELHVEDGLTVRAVLEAAVTVSDNTAANLMFDLIGGP -RGLDEALEDVGDDTTEAVRREPDLNDYTPGDVRDTTTPRAIASSLAAFAVGGELKPSDER -LFNNMLLRNTTGDALIRAAVPASWRVGDKTGSASYGTRNDIAVVTSPGRTPVVVAVLTRH -STADAATDDGLVAEAARAVVGSw ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Legionella feeleii TaxID=453 RepID=A0A378IV15_9GAMM ----IQEKLAKLEASSGGKIGIYAINTANGQKI-HYRANQRFPMGCTSKVMGVAAILKKSM -SDPTLLSQRISYTKKDLTNWAPIAEKHLYTGMTVAELCAASISYSDNTAMNLLVKKLGGL -EKINDFARSIHNDTFRQDNGWPEAMSGGPNNVYDSSTPKAMAQSLQQLALNNVLAKPQHE -LLLSWLKSNTTGDKRIRAGVPKGWIVGDKTGTGMYGTTNDIGVIWPPQCSPVVIAVYYTN -NNKEAIQRNDIVSSATRLVIDGf ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001428302F ---AADAAFTALEERFGARLGVHAVDTGTGTEV-SWRADERFAYASTIKAPLAAALLDRVG ---VAGMDRAVPIEAVDILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDSDERA -LFTGWLTATQTGGTLVRAELPADWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK -DQQDADADDALISGAAKAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1554424.7 TaxID=1834082 RepID=UPI0009ED5140 -----YKRLADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG -ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP -AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSEVDTSTPKDMATSVQALTVGDALAPPQRA -QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ -NRREANAREDIVASATDAILGRf ->[subseq from] class A beta-lactamase n=1 Tax=Endozoicomonas ascidiicola TaxID=1698521 RepID=UPI000BA45C8C --qAVEKQVKKSENALSAQISVAMMNSATDEVW-SYNGNKRVPITSTFKTLLCAKLLQDVD -QERRALSDKVKLEKTMLVDYSPVIEGFLGEYVTLGQACSATMQTSDNTAANIVLENVGGP -NALTKFIRSYGDQVTRIDRFETELNEGTPGDPRDTTSAEAMLHSIDTLLFGDALSVSSKK -QLTQWMIQNTVTGNLLRSVLPEGWVIADRSGAGGYGTRSINAVVWPEDGNPWVITIYVSN -TKAAFEERNKAIVEIGKTMFR-- ->[subseq from] Beta-lactamase n=1 Tax=Sandaracinobacter sp. PAMC 28131 TaxID=1715348 RepID=A0A501XUI2_9SPHN ------ANLQALEAQAGGRLGFALLDTGTGKII-GHRMDERFGMCSTFKLPLAGLVLQAAE -RGELKLDTLLPITQADLVPHAPETGPNVGKAMRIRDLARVAQMTSDNVAANLLIKQLGGP -AGVTKRLRALGDKATRLDRMEPEMNRVIGNDPRDTTTPRAMAETVARLLTNDALTPASRK -LLGQWMADTQTGMRRLRAATPPGWTAGDKTGTGMTKRVNDVAIFWPPKGAPLVAAAFYEA -PGNSRPQDEAVLVQAMQIA---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-2256-B3 TaxID=2022490 RepID=A0A260IH38_9NOCA -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREVGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRMVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C578FB ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDKKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Ascidiaceihabitans donghaensis TaxID=1510460 RepID=A0A2R8BBR6_9RHOB -----ARTVATLEKTLDARVGVYLFDSGTGWQW-GHRETERFLMASTFKPLLCGAILAQAD -AGALNLEDRIDVRKQDVVPYAPVTETHVGHSMSIHDLCFATLDLSDNTAANLLTNRLGGP -QNVTAFLQAIGDDVTRLDRLEPDVNTFVPNDPRDTTSPIAMTHSWATLLLGDALQPKSAT -QLAEWLSHGGVTGQFIRAHAPQGWQVLDKSGGGRHHTRNLMAMVTPPGEPPVFVAIFVSD -TPADWDTRNAAVSTLGAAVIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA4DB7 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPIAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEIGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CR10 TaxID=2562314 RepID=UPI0010BFF504 -----DERLKALERKHNVLIGFSAVEVPSGRWL-AHRAKDRFSMCSTFKAYAAADVLRRSE -RGELMLTDTVPVEPTDIIAHSPVAETRVGMTMTLAEMCQAVLQQSDNGAANLLLRVLGGP -PAITAFARSIGDEESRLDRWETELNSAVPGDPRDTTTPLAIGIGFRNLLTGDVLSPAGRR -QLDDWMRANQT--SSMRAGLPKGWTSADKTGSGDYGSTNDVGIAYGPSGQQLLLSIMVRS -AVPDAQNQRPLIGEVAAFAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri (strain MJ11) TaxID=388396 RepID=B5FDI3_ALIFM ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Dermacoccaceae bacterium C5-26 TaxID=1660198 RepID=A0A563DVB1_9MICO -------DLDALESTFGGKVGLYALDTGTGAAV-RHRADERFLMCSTYKVLVVSATLSQAQ -ARPRLMDQVVHFRAAEVLPYSPVTSTHTAESMTVSALCDAALTRSDNTAANLLVDLVGGP -TSVTKYVRTLDDPETRVDRDEPALNIA--DGSLDTTTADAIGADLLKLVLGDALTAQNRK -LLTAWLKANTTGDRSIRAGLPRGWAVGDKTGSGVHGEVNDVAVIWPPRRAPLIMAIYTRP -TDPGSTEGYHAVARATRIALK-- ->[subseq from] Beta-lactamase n=1 Tax=Virgibacillus dokdonensis TaxID=302167 RepID=A0A2K9J262_9BACI -----ESEFRLLEKEYNAKLGIYAVDTSNGKTV-SYQAEDRFAYASTHKALAVGVLLQKLT ---LKQLKETVLIKEGDLVNYNPITENHVNKHMSWKELSDASIRYSDNTAANHILNRIGGP -NGFKKALGGIGDNVTNPERMEPELNLVNPGEIKDTSTPKALATSLKAFTIGNVLPKEKQD -LLVDWLKRNTTGNHLIRAGSPRGWEVGDKSGAAPYGVRNDIAIIWPPNKAPIILAILSSK -EEKNAKADDKLIAEATKKVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Thiomicrorhabdus sp. Kp2 TaxID=1123518 RepID=UPI0004282684 ---SLKNTIISIEKQSHGKIGVAVLSTQTQQYW-SYRGNERFALMSTFKTLACAKMLADSD -HNILNKQQTALVDKTKMIPWSPITEQYIGKQMTLEKLCEAAMLNSDNTAINLVLSHIGGP -AAVTKYLQQNGDSVTRIDRIEPELNTAFLNDPRDTSTPLSMVNTLHKLLYGSLLSNASKE -QLKNWMMNNQVSDALLRSILPSNLFIADRTGAGNNGSRGITAVIWGKEKQPLIISIYLTQ -TTLSIQERDKVIVKIGERILQKy ->[subseq from] Class A beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A659GSJ3_CARML --kTIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQKIMINQEDLVDYSPITEKYVGVGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPNRKPIVLVIFSNK -TNKDDAYQDELIAKFAKLVGDYf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1081908.1 TaxID=1834066 RepID=A0A1A3QNA6_9MYCO ------KRLADLERQFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG -ADSNLLQQQVHYSERDLITWSPVTRKNIAGGMTFAALAEAAISDSDNTAMNLITKALGGP -AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSDLDTSTPKDMATSVQILTVGDALAPPQRA -QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ -NRREANAREDIVASATDAILDQf ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JKN7_9ACTN ---DVHKELRKLEASYQGRIGAFAIDTGTGRTV-GYRTHERVPSNSTFKAILCGAILHKAR -TDPGLLNRTLHWTKEEVVDGSGITGKNIKNGMTVARLCEATITTSDNTAANVLLEQVGGP -RGMTRYYRSLGDPVGRLDGYEPELNHWNPGEKHDTVAPAFMARDLQKLTVGKALVPQDRQ -QLATWMKATTTGDERIRAGVPKGWTVGDKTGTADYAAANDIAIAWPPSGAPVIIVVFTHR -AAKDAKFDNKVIAQTTTVLM--- ->[subseq from] class A beta-lactamase n=1 Tax=Kocuria sp. 36 TaxID=1415402 RepID=UPI00101D43A7 ----VVSRIRELERGLDGEIGVHAFDTSTGACF-GYRDRQPFLLCSVSKVLVAATVLDLAA -DDPQLLGKRLTITQDDLLPYAPVTSQHLEGGMTVEELCAAALTVSDNTASNLLLEQCGGP -ETVTAFVRSTGDVTTRLDRIEPDLNDA--SGTLDTTTPAAFSETLNRLTLGDALAASGRD -KLVGWMKESTTGAEQIRAGLPEGTLTGDKTGSGTHGESNDVAVIWPKQGAPVIMSVFTKS -QRDDTTGQKAAIAGTARAVF--- ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149ULY8_9PROT ----VASVLSEYEDATGGRIGVYARNLVTGQAL-TWRENERFAVCSTFKASLVALVLLRVD -QGKERLEDVAPYTQADVEKYAPVAQAHVEAGLTVRTLCQAALEQSDNACANLLLARVGGP -AMLTRFWRSLGDTKTRLDDWEPVLNRTPPGGLRNTTTPRAMAGTLEHVLFGDTLSVSSCM -LMTDWLKGCRTGTHRLRAGLPEGWGVGDKTGNNGRDAVSDIAVAWPAPQRPIILSVYTRG -GHPVEEQFRTAFAGIGRMV---- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1N6JKE4_9BURK ----AESPLADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGLLAAQVLARVD -SGKDSLERFVRYTEKDLIFTSPVTKANVAQGMSVGALCQAIVEVSDNTAAILLMRSVGGP -AALTQFVRSLGDTVTRSDRYEPESNQY--SGVLDTTSPRAITQAVSRILLGDVLSPPSRA -QLESWMVACKPGLNRLRASLPADWRAADRPGTSVEEETNDYAVVRPPGRAPLLVAAYYDA -PGVSMDAREAVLREAGAVFV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Syntrophobacteraceae bacterium TaxID=2052185 RepID=A0A3B8HNC1_9DELT ------------------------FDASTGTTW-NYRGDERFPLNSTHKTFSCAALLAKVD -GKSLSLGQSVSISKEMLVTYSPITEKSLSPEVTLGKICQAAVSYSDNTAANVIFDAIGGA -TGFNAYMRSIGDEQTRLDRKEPELNEGTPGDVRDTTTPNAIVNSLRKILLGDGLSVSSRS -ELTQWMLDDQVAGALLRASLPSDWKIADKTGAGGYGSRSIVAVIWPPSKQPLVVGIYITQ -TKASMQASNQAIARIGVV----- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DAC4B1 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=UPI0013EF6548 -------FLKQQEQQLNARIGMAVVNAQGEMMF-GYRQDERFPLTSTFKVLACAALLDKLQ -QTGGSLDEHVTIKPSELLDYAPITKHYLAPALSLRMLCAAAVSYSDNTAGNRILAYLGGP -EAITHYMRRMGDEVTRLDRVEPTLNEATPGDARDTSSPAKMAAGLQKILTSSSLSPAYRE -TLTTWMREDKVGDALLRAALPTDWAIADKTGAGGHGSRAIIAAVYPPKQPPFYVAMYITQ -TIAPMKTADATIAATGKRLF--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. Leaf233 TaxID=1736302 RepID=UPI00070A4EAA -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. FUKUSWIS1 TaxID=1379701 RepID=UPI000A68A52C --------VAAYEAASGGHVGIYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALVPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLRQVGGP -AALTAYWRRLGDDVSRLDDIEPFLNRAPPGGLRNTTTPRAMAATIGRLTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPQGWVIGNKTGNNGRDAAGDVGVLWRDPDTPIIISVYTRG -GTPTEAQFKTLFSKVARGVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. C1-24 TaxID=2495913 RepID=A0A5A7S5U3_9NOCA --qKLDSRLAALEQQYNARVGVAVDRPSDGAEY-RHRGDETFAHCSTFKVYAASALLRLVA -AGSASLDTTVVIDAAAVVANSPVTAKAAGSPMSMGDLCLAALTQSDNTAGNYLLHAIGGP -PAITAFARSVGDTTTRGDRFETDLNTAIPGDLRDTSTPAGLAAGFGATILGDGLQPDGRA -QLQDWMRRSLTSAARIRAGLPQGWTSADKTGSGDYATVNDAGVVWDPAGKPVVVAILTTT -RSQDAPADGKLVVDITAAIIETf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004BD7D39 ---QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS -VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP -KKLEAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVVLEKGLGKQERK -LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR -TEEDASYDDRLVSEAATVVAD-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces albus TaxID=1888 RepID=A0A4Z0VM90_9ACTN ---QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS -VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP -KKLEAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVVLEKGLGKQERK -LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR -TEEDASYDDRLVSEAATVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI0003736022 ------ESIEQIESRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDSETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSVTRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=2 Tax=Methylosinus sp. C49 TaxID=2699395 RepID=A0A679F082_9RHIZ ----IEAELEELEARSGGRLGVAVLDSATGRIM-GNRIDERFAMCSTMKALAVAHVLARVD -LGKERLDRRIVFTEHDLVTPYKATQPHVGPEMSIEALCEAAITVSDSTAANLLLTSFGGP -TALTAYLRSLGDHVTRSDLFELKLNVVKPGETHDTTTPRAMVGTLHRLLLGDALSEASRA -RLTSWMVEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDIGVIWPPGREPIVVAAYLGN -APGSTAAQEGVLAGVARIMAE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. GF69 TaxID=2267251 RepID=A0A329LZ06_9MYCO ------DRIGAMERSNNALIGVFATNLDTGRTV-AHRAQDPFAMCSTFKGYAAARVLQKAE -RGELALTDRVIIDQGDIVPNSPVTQTRVGQAMTLTELCQAALQQSDNAAGNWLLRVIGGP -SGITDFARSIGDERSRLDRWETELNAAVPGDPRDTTTPEAIGGGYRSILLGGVLAEPQRQ -QLGDWMRANQT--SSVRPALPPGWTTADKTGSGDYASTNDVGIAFGPDGERLLLAIMTRT -AGADAPNNRPMVAELAKQLV--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001269D020 ---AADAAFTALEERFGARLGVHAVDTGSGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILAYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVARTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERA -LFTGWLKATQTGGTLVRAELPTEWTVGDKSGSGAYASRGDIAVIWRPDAAPIVIAVHSSK -DQQDADADDALISGAAKAAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptacidiphilus oryzae TaxID=348818 RepID=UPI000A036EAF -hpAAAAAFAALERRYRARLGVYAVDTGSGRAV-AYRADERFGYCSTFKALAAGLILARAT ---DARLGTVLHYRRSDLLAHSPVTSEHLAEGLPLRAVLAAAVQYSDNTAGDLLLKELGGP -SGLAAALRGLGDRVSLPARTEPALNVIAPGDTRDTSSPRAFGTDLRRLALGDLLPAARRA -QFAALLRGNTTGGAYIRAGVPAGWRVGDKTGSSTAGIRNDIAVLWPPRGAPIVLAVMTDR -GAAQPPATDPLIADATRSAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C4EAE7 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. OK233 TaxID=1882795 RepID=A0A2C9BWF4_9BURK --------LADIERRHGGRLGVFAIDTGSGRTL-THRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLGRRVTYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITNSASKILLGNVLSPQSRA -QLENWMIACKPGLNRLRAALPPDWKAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA -PALDMPAREAVLREVGAVFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI00117EAD56 ---AADAAFAALEERFGARLGVHAVDTGSGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERT -LFTGWLTATQTGGTLVRAELPAHWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK -DQQDADADDALISGAAKAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudooceanicola marinus TaxID=396013 RepID=A0A1X6YHV4_9RHOB --eALSNTVARIEEQLDARVGLSLVETGSGWSW-SHREDERFLMNSTVKVPVCGAILARWD -AGTLSLSEALPVRKADLVPYAPVTETRVGGTMTLDQLCLAAIDMSDNVAANLLIGHLGGP -EAVTQFFRSVGDITSRLDRIEPELNDFTPGDERDTTSPAAMSETLRALLLSDALSPQARG -QLAEWMRHGGVTGALLRAEADDDWLILDKSGSGSH-TRNLVAVIQPDGEAPWIATMFVSD -TDAEFEARNEALKDLSRAVV--- ->[subseq from] Beta lactamase protein (Class A), carbenicillinase n=2 Tax=Rhizobium TaxID=379 RepID=N6VAW1_9RHIZ ---------------------------AGGKRI-EHRAGERILMCSTFKALVAALVLARVD -KGEEKLDRRIRYTKSDLLGNSPATEANVGNTMTVAELCAAAVTLSDNAAANLLLASFGGP -KALTAFCRSLGDEITHLDRVEPELNYDTPDDQRDTTTAAAMLENLRRLLFTDVLSLASRS -QLAAWLIMTKTGDARLRAGLPKDWLVGDKTGTSDVGNANDIAVLWPSDRAPIIVTAYCEI -PGISAAERNAVIAEIGRIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Methylosinus TaxID=425 RepID=A0A177PLT1_9RHIZ ----IEAELEELEARSAGRLGVAMLDCATGRII-GNRIDERFAMCSTMKALAVAHVLARVD -LGKERLDRRIVFTERDLVTPYKATHPHVGPEMSIEALCEAAITVSDSTAANLLLNSFGGP -TALTAYLRSLGDHVTRSDLFELALNVVKPGETHDTTTPRAMVGTLRRLLLGDALSQASRA -RLTSWMVEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDIGVIWPPGREPIVVAAYLGN -APGSTAAQEGVLASVARIMAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Parvularcula sp. CL28 TaxID=2580516 RepID=UPI0012BC8967 ---------------ASARIGVLAQDLSRSRRI-AWRADERFAMCSTFKWLLAAQILAEAD -AGTLLLSDMVTFQEHDLVPYSPVTGPLAVEGASVATLCAAAVSKSDNTAANLLLRLVGGP -HGFTRKLRSWRDGVSRLDRWEPDLNENRSGDARDTTSPAAMADLLRRVLFGDTLTGDSRK -LLMAWMEAADTGLTRLRAAIPEGWAAGDKTGTSNNGANNDVAYFRRPDGAPIVIASYINA -PNSDRSTINAIHAEIGMLIIDIf ->[subseq from] Beta-lactamase n=1 Tax=Myceligenerans xiligouense TaxID=253184 RepID=A0A3N4YMR1_9MICO -------AFTGLEEAYQARLGVYARDTGTGRHV-AYRADERFPFLSTIKTIAAAEVLEDST ---RADLGTTILYGPGDLVEWSPETEEHAGEGMPLGDVLRAAITASDNTAANLVLDRLGGP -HALEARLRGDGDDVTSVDRPEPELNEWSPGETRDTTTPRAIAAQFQEDVLGDELSEPMRG -FLVRALRDNKTGDDLIRAGVPEGWDVGDKTGSAG-GMRNDLAVLVPPGGDPIILAVYTHT -NDPDAESDPALIAEATRVVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0013658B56 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVITVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. michiganensis (strain NCPPB 382) TaxID=443906 RepID=A5CUH3_CLAM3 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGQ -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDADADDALISGAARAAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIB 8712) TaxID=395963 RepID=B2IKN6_BEII9 ----IQARLRELESRSGGRFGVAVLDTATGGLV-GNRIDERFAMCSTCKVLAVGCVLARVD -RGEERLDRRITFTERELVSPFKATSPHVGPEMTIAALCEAAITISDSTAVNLLFASFGGP -AALTIYLRSLGDPVTRLDHMEPALNIVKPGEIHDTTSPAAMAGTLRQLLLGDALSDTSRA -LLTGWMIGAKDATHRLRDGLPAGWRIANKPGTWEKIATNDIGVIWPPGRAPIVVTAYLGE -VPGSVESQEAILADVARIVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Methylosinus sp. sav-2 TaxID=2485168 RepID=A0A4R8HRK7_9RHIZ ----IEAELEELEARSGGRLGVAMLDCATGQII-GNRIDERFAMCSTMKALAVAHVLARVD -LGQERLDRRMVFTERDLVIPYKATQPHVGPEMSIEALCEAAITVSDSTAANLLLTSFGGP -TALTAYLRSLGDHVTRSDFFELTLNVVKPGETHDTTTPRAMVGTLRRLLLGDALSEASRA -RLTSWMVEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDIGVIWPPGREPIVVAAYLGN -APGSTAAQESVLASVARIMAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001365578F ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDYTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPVVIAVHSSK -DQQDAKADDALISGAAKAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1081908.1 TaxID=1834066 RepID=UPI0012E9C497 ------KRLADLERQFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG -ADSNLLQQQVHYSERDLITWSPVTRKNIAGGMTFAALAEAAISDSDNTAMNLITKALGGP -AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSDLDTSTPKDMATSVQILTVGDALAPPQRA -QLLGWMRNNTVGYKRIRAGVPLGWLVADKTGSGAYGIANDIGIVSSPYCKPIVLAIYTVQ -NRREANAREDIVASATDAILDQf ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000CE7B851 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAMPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDVDERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase class A n=3 Tax=Mycobacterium bohemicum TaxID=56425 RepID=A0A0U0WBS3_9MYCO ------DRLDELERQYGAYVGVYALNIDTGRSL-AHRDGDPFAMCSAFKAYAAARVLQMAQ -RGELDLQQAVFVDPATLLPNSPVTAPAAGHPLPLAQLCAAALQRSDNAAANLLLRAIGGP -PAITEFARSIGDDRTRLDRWETDLNTAIPGDPRDTSTPRAFGGGIQSLLTGTVLDEPRRR -QLEDWMRANVT--STMRAGLPAGWTTADKTGTGDYGSTNDVGIAYGPDGQRVLLSLMTRS -QAQNADPLRPLIAEVTRTVL--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae (strain NBB3) TaxID=710685 RepID=G8RLV6_MYCRN ----VEALIQGLEQKHNASIGVFATNLASGKTV-AHRAQEPFAMCSTFKAYASGRILQMAQ -HGELSLDDPMFVDPAGILPNSPVTAPRAGGEMTLAELCQAVLQQSDNAGANILLNRIGGP -QAITAFARSIGDHQTRLDRWETELNSAIPGDLRDTSTPEALGAGFRALLDGDVLAPPQRG -LLDDWMRANQT--SSMRPGLPAGWTSADKTGSGDYGSTNDVGIAYGPEGQRVLLAIMTRT -QANDAENLRPLIGEVTTLVM--- ->[subseq from] Class A beta-lactamase n=1 Tax=Parvularcula sp. CL28 TaxID=2580516 RepID=A0A6A8QVL1_9PROT ---------------ASARIGVLAQDLSRSRRI-AWRADERFAMCSTFKWLLAAQILAEAD -AGTLLLSDMVTFQEHDLVPYSPVTGPLAVEGASVATLCAAAVSKSDNTAANLLLRLVGGP -HGFTRKLRSWRDGVSRLDRWEPDLNENRSGDARDTTSPAAMADLLRRVLFGDTLTGDSRK -LLMAWMEAADTGLTRLRAAIPEGWAAGDKTGTSNNGANNDVAYFRRPDGAPIVIASYINA -PNSDRSTINAIHAEIGMLIIDIf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI000C825A04 -------SIAKIESRISARIGVAVYDSATEQIW-NYKGDERFPMMSTFKTLTCANLLYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -NGLTEFLRFMGDRKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWRIADRSGAGAYGSRAITAIVWSETHAPLIISISLTE -TELTIPERDTVINEIGELLM--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00099CFF93 ---QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS -VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP -KKLDAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVVLEKGLGKQERK -LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR -TEEDASYDDRLVSEAATVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00056BFFFF ----LEEQFAALEQRFDARLGVFAVDLDSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTETRVVEAEDKVPGSAIDW-EAGQAVTLEQLCAAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTGGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLAADGRRILAVVLSRT -ASPDAAAMNELVADAVREIV--- ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A371YJC9_9GAMM ------NSIKEVEQNLGAKVGVSIYSVSDGYLW-HYNGDSRFPLMSTFKPLACAKLLHDVE -TAKLSIDRSVKIEEQDLITWSPITEKLVGESFSLKQACTAALVMSDNTAANIVLDGISGP -SELTLFMKELGDEVTRLDRIEPHLNEARSGDERDTTTPNAIVKSLGKLLYGEKLSSGSKE -QLIEWMAGNKVSDSLLRSVLPEGWSIADRSGAGGFGSRGITAAIWSNEQQPLIVAIYLTQ -TEASFDERNKAIAKIGREIFASy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C73BA -----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVITIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 32-66-10 TaxID=1970437 RepID=A0A258H137_9SPHN --------FDRIRAETGGRLGVAVYDSGTGRRF-SDGAEARFAMCSTFKMPLVAAVLARVD -RGELNLANEIRFGEADLLDYAPVVKANLAKGMSIDALCEAAVVMSDNSAANLLFGQIAGP -RGLTKFIRDAGDKLTRSDRDEPSLNNVRNGEVRDTTTPDAMLWLMNRLLLGDVLTPASRA -KLIGWMEASPTGKARLRAGLPKDWRVGDKTGTSGEGYFNTIAIATPPGRKPILIACYLDA -PGLESAKANAAHAKVGELVG--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. OK233 TaxID=1882795 RepID=UPI000BE46AFB --------LADIERRHGGRLGVFAIDTGSGRTL-THRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLGRRVTYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITNSASKILLGNVLSPQSRA -QLENWMIACKPGLNRLRAALPPDWKAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA -PALDMPAREAVLREVGAVFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C4F17 -----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio splendidus TaxID=29497 RepID=UPI000808CC66 ------ESIEQIEFRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. Sr39 TaxID=1259198 RepID=A0A4V3ISV5_9MICO ---NADAKFTNLEAAHDARLGVYAVDTGTGEEV-VWRSDERFAFASTSKALSAAALLDSVG ---IAGLSADVDVAAEDIVSSSPQTQQHVGASMTLGELAAASVQHSDNTAANLVVEHLGGP -AGFDSALSRIGDDTTEATRTEPSLNEWVPGDRRDTTTPRALTMDLRTYVLGDVLSGEERE -LLTTWLIDHSLGDTLVRAGTPQGWTVGDKSGAAAYGTRNDIAVIWPPSGSPIVIAVMSSR -TEADAEYDDALVAAAASAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA9868 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGKMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDKKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050BEAD0 -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 14-2686-1-2 TaxID=2023145 RepID=A0A260TYZ9_9NOCA ----LEEQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTETRVVEAEDKVPGSAIDW-EAGQAVTLEQLCAAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTGGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLAADGRRILAVVLSRT -ASPDAAAMNELVADAVREIV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. PBTS 2 TaxID=1653479 RepID=A0A143QHA6_9NOCA -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D8BEE3 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGCGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D91D80 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDETRLDRIEPELNESKNGDKRDTTTPVAMSTTLNALLFGDTLNQQDKQ -TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAIWNGKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDM9_9BACT ---TLSKAVQAEEARLGARIGMALFDAKDRTRW-AHRGDERFPLNSTHKSFSCAALLKQVV -RRVLALENVISIERASLVTYSPVMEKT-GGQVTLREACAASVSWSDNTAANIVTDAIGGP -QAFTVFMRDIGDPHTRLDRKEPEMNEATPNDLRDTTTPNAIVESLRRIILGDVLREDSRA -LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKDRDPVVVGIYITQ -TSAPMADSNAAIARLGSVLAD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces turgidiscabies Car8 TaxID=698760 RepID=L7F7J9_9ACTN ----------------------FAHNLGTRQTI-RHRADERFPVCSLFKTLAAAAVLRDLD -RSGEVLSKRVHYTADDLVDGSAETEKHLTEGMTVAELADVAIRFSDNTAGNLLLRELGGP -TAITRFARSVGDRATRLDRWETELNSAEPWRITDTTTPYAIGRTYARLVLDDVLNRPDRE -LLTHWLLTNTTSDNRFRLTLPPTWTIADKTGAGSYGTNNNVGIAWTQKGTPVVLAVQTTK -PAQDAAPDNPLVAETARLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C55602 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGKMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DA5E06 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYNSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2470-1b TaxID=2023149 RepID=UPI000B9BE5AF ----LEEQFAALEQRFDARLGVFAVDLDSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTETRVVEAEDKVPGSAIDW-EAGQAVTLEQLCAAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDGQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTGGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLAADGRRILAVVLSRT -ASPDAAAMNELVADAVREIV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. EPa45 TaxID=1545728 RepID=A0A0G3IPI3_9MYCO -----GQRIAALEKRHNAVVGLYAQNLDSKTEV-AYRDGDLFAMCSTFKAYLSARVLQKAQ -AGELLLTDSVLVEPADLKPNSPRTEPNVGQRMALSDLCAAALQVSDNTAANLLLRTIGGP -PAITAFARSIGDDRSRLDRWEAELNSALPDDPRDTSTPRALGGGIARVLTGDVLDEPHRK -QLEDWMRANTT--SSMRGGLPPRWTTADKTGSGDYASTNDVGIAFGPNGEHVLLAIMTRT -KSDDAEPLRPLIAEVATLVL--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas panacis TaxID=1560345 RepID=A0A1B3ZEY5_9SPHN ---TIEARLKALETRSGGRLGVAILDTATGEMM-GRRLDERFALCSTFKALAIAFTLARVD -RGEENLDRRIYFTQKDLVTPFKATRPHLADGMTVAELCGAAATVSDSTAANLLLAGFGGP -SALTAYLRSIGDHTSRIDRTELALNIVKPGETHDTTSPRAMAATLRHILLGSALSPASRA -RLIEWMMASKDAAQRLRRGLPVGWRIANKPGTWEGVSTNDVGVIFPPDRPPIVVAAYLGG -GHGSVADQEAILSEVARIVA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio gigantis TaxID=296199 RepID=A0A5M9P4V0_9VIBR ------QSIQGIESRVSARIGVAVYDSATEQTW-NYKGDECFPMMSTFKTLACANLLYDAE -KKGLDLESKVGIESGDLIVWSPVTKALVDKEISLKDACTATMEMSDNTAANVVLSGIGGF -NGLTEFLRLIGDSKTRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNALSEESKA -QLKTWMMNNKVSDGMIRSILPDGWRIADRSGAGAFGSRAITAIVWSETRAPLIISISLTE -TELTIPERDAVINEISELIFDEy ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. LHW63021 TaxID=2231787 RepID=A0A365HC20_9ACTN ---DVRAELRRLEASFQGRIGAFALDTGTGRTV-GHREHERFPGNSTFKAILCGAILARAR -ADPGLLERTLRWTKDDLVAHSPITRKNVEGGMTAAQLCHATITTSDNTAANVLLEQIGGP -PGMTRYYRSLGDPAGRLDRWETELNVWRPGERRDTITPALMARDLHRLTLGPALVPQDRQ -RLVGWLRAATTGAARIRAGLPAGWTVGDKTGTGGHPTASDIAIAWPPSGAPVVIAIYTYR -TAPGGTVDDRVLARTASLLA--- ->[subseq from] Beta-lactamase n=1 Tax=Ideonella sp. MAG2 TaxID=2083017 RepID=A0A523Q3I2_9BURK ---ALPQALAALEQRAGGRLGVAVLDTGNGILL-GHRQDERFGLCSTFKLALAGVVLRLID -QGRLKADQWVPYTQADLQSYAPVAKQHLAQGMTVQALAEATQTTSDNTAANLLLGLMGGP -AGLTQHLRDLGDTTTRLDRLEPAMNLVPVGELRDTTTPSAMARTTAALLTGQALSPASRA -RLADWMVATQTGLKRLRATLPPGWRAGDKTGTAMVDKYNDVAIFWPPGRAPVIVTAYYDT -AKAHRAQDEAVLAEVGRWAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Myceligenerans xiligouense TaxID=253184 RepID=UPI000F4E96A0 -------AFTGLEEAYQARLGVYARDTGTGRHV-AYRADERFPFLSTIKTIAAAEVLEDST ---RADLGTTILYGPGDLVEWSPETEEHAGEGMPLGDVLRAAITASDNTAANLVLDRLGGP -HALEARLRGDGDDVTSVDRPEPELNEWSPGETRDTTTPRAIAAQFQEDVLGDELSEPMRG -FLVRALRDNKTGDDLIRAGVPEGWDVGDKTGSAG-GMRNDLAVLVPPGGDPIILAVYTHT -NDPDAESDPALIAEATRVVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Microbispora triticiradicis TaxID=2200763 RepID=A0A372PJN3_9ACTN ---AVRKALRRLEVSFRGRIGAYAIDMATGITI-GYREGERFPLASTFKAFAAGAVLAGTT --EAELTRQVVRWTAGEVKPHSPQTGRHVADGMTLAALCRAAIVHSDNTAGDLLLKRIGGP -RGLTRYFRSLGDPVSRLDRWEPELNVWSPRERRDTTTPVSIARDLRALTTGGALDAADRS -RLVGWLRGNTTGDARIRAGLPPKWIVGDKTGTGGYGTASDIAVVWPADAAPIILAIYTNR -LTPGGSADDEVVARTATVLV--- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. HPH0547 TaxID=1203592 RepID=S3BQE8_9ACTN ---QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS -VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP -KKLEAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVILEKGLGKQERK -LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR -TEEDASYDDRLVSEAATVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2483-1-2 TaxID=2023147 RepID=UPI000B9C5A58 ---SAEQNYVDLEARDTARLGVSAVDLGSGYTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGALQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTPASRD -RLLAWMTDTQTSDGRFRAGIPEQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNSLVADATRAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Listeria newyorkensis TaxID=1497681 RepID=UPI00066A06E1 --eEAKAELKKLEEKYGATLGIYAVNTADKKKI-SYNDQERFAYVSTYKAIAGGLLLKNLT ---TEQLNKRIYFSKEDLVDYSPVTEKHVDSGMTVKEIINAAMTYSDNTAGNILFQQLDGP -KGYQKELAKIGDKTTQADRLEPELNEAVPGDKRDTTTPEAMANVLSFLTTKGNMASDRLD -YFKQTLIDNTTGDKLIRAGVPAGYTVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK -SGKDDEYNDQLIADAAKVLSNYf ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora sp. TRM65233 TaxID=2654637 RepID=UPI0012E9E30D ---QATEEFTALESTFGGRVGVYAVDTATGRST-GHRADERFLMCSTAKVLMAAAALRATP ----DLMDRLVRYTPADLVAHSPVTEQHVGTGMTVAALCEATLTVSDNTAANLILSTLGGP -QAVTDYVRTLDDPTTRLDRTETALNTTTPE-GLDTSTPAAFAQTTTALLVDGALPARARD -TLTAWMKASTTGLDLIRAALPPTWTTADKSGSGAQGEVNNVAVTWPPNGKPWVVAVFTAP -DDPESDGSREVVARAAAIALK-- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A1E5AMR4_ALIFS ---SLTQNIEAIELSSGGYIGVSVLNTETNKIW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNNWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFNEf ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-235-1A TaxID=2022508 RepID=A0A260BN43_9NOCA ----AEQHYLELEDRDTARLGVSAVDLASGSAE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGDLQLTDTRTVTALDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGA -DALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLSAASRD -QLLAWMADTQTSDARFRAGVPDQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSTT -TSEDSPAMNTLVADATRTVVDE- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DAA64C ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLHAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=2 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001366402E ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDYTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPVVIAVHSSK -DQQDAKADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia multivorans TaxID=87883 RepID=A0A1W0YPC7_9BURK ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMNVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAATRGAGGYGTTTDVAVLWPPSRAPIVMAVSYTQ -PRADAAPRSDVIVSAARIVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A4Q5XYJ6_9PROT ---KASARIAAIEARLGGRIGVSAIDTGSDAEI-NHRAQERFAMASTFKWLLAAGVLKRCE --EGLNLDAVMYFTPSDLLPTSPVTSAEISATLSVEQLCEAIVTVSDNAAANLLLVPMFGP -EGLTRFLRESGDPHTRLDRVEPELNENRPNDLRDTTVPHAMARTLRRLLTDEVLNANSRA -RLTGWMEKASTGLDRLRAGFPDSWRAGDKTGTGGNGSHNDCCIVWPPGRSPIVIASYLSE -SAAPNIDKAAAHAEIARIIVEEf ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C45E14 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHPPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. ERR 942 TaxID=2572676 RepID=A0A560L684_9RHIZ ---SIEEDIRLIETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD -QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP -AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDMLSPRSRG -LLTDWLVNGQDATQRLRKGVPAGWRIVNKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH -APGSIESQEAVLADVARRVCD-- ->[subseq from] Beta-lactamase n=2 Tax=Listeriaceae TaxID=186820 RepID=A0A099W3W8_9LIST --eEANAELKKLEEKYGATLGIYAVNTADKKKI-SYNDQERFAYVSTYKAIAGGLLLKNLT ---TEQLNKRIYFSKEDLVDYSPVTEKHVDSGMTVKEIINAAMTYSDNTAGNILFQQLDGP -KGYQKELAKIGDKTTQADRLEPELNEAVPGDKRDTTTPEAMANVLSFLTTKGNMASDRLD -YFKQTLIDNTTGDKLIRAGVPAGYTVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK -SGKDDEYNDQLIADAAKVLSNYf ->[subseq from] Beta-lactamase n=2 Tax=Vibrio splendidus TaxID=29497 RepID=A3UMM7_VIBS1 ------ESIEQIEFRVSARIGVAVYDSATEQTW-SYKGDERFPMMSTFKTLACANLLYDHE -NEGLYLESKVGVKSDELIAWSPMTKAFVGKEISLTGACAATMEMSDNTAANIVLAGIDGP -NGLTEFLRSIGDRETRLDHIEPDLNHARPGDERDTTTPNTMVKTLNELVYGNVLSEESKA -QLKTWMMDNKVSDGMIRSILPDGWNIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia sp. Bp8963 TaxID=2184547 RepID=A0A3N8LYZ1_9BURK ---AAESPIADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGILAAQVLARVD -AGNEQLDRLVRYTEQDLIFTSPITKANVARGMSVAALCDAMLVYSDNTAAILLMRSIGGP -AGLTGFARGLGDTVTRSDRYEPDSNDY--GGERDTTTPRAIVTLARSVLLGNVLSPGSRE -RLERGMIDCKPGLNRIRAVLPAGWQAGDRPGTSLQGETNDYALVRPPGRAPLLVAAYYDA -PGVGMDAREAVLREAGTAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Casimicrobium huifangae TaxID=2591109 RepID=UPI0012EB2681 -----ASELATLERKAGGRLGVAILDTGTGRYT-GHRLAERFAMCSTFKLPLAAIILREVD -RGNLRLDQFVPYSKRDIVAHAPITSRQLADGMSIEALARAAQMESDNVAANLLLSLIGGP -AGFTSTLRSLGDSTTRLDRTEPSLNLVTPGDLRDTTTPAAMCQTIAHMLTANWLKPASHD -LLVSWMMATETGLKRVRAGFPQGWRSGDKTGTGMHDKYNDVAIVWPTGKAAVVVSAFYEG -PMRMRDEDQAVLAEAGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis valliformis TaxID=239974 RepID=UPI000584B82A ------AEFGALEEEFDARLGVYALDTGSGEEV-AFRANERFAFLSTFKALLAGVVLSENS ---LEEMERVVEYGEEDLVDHSPVTEENVGSGMSLLELSDATVRYSDNAAANLLLAEVGGP -EGFGEALVEAGDEVTNPVRWETELNDVGPGEERDTSTPEALAGSLEAFTLGDVLQEDRRE -VLVDLLVRNTTGDELIRAGVPQGWVVGDKTGGAG-GMRNDIGVVWPEGGDPIVVAVLTSR -NEEGAEFDNALVAEATEVVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Paucibacter aquatile TaxID=2070761 RepID=A0A2N8KUD1_9BURK ----FDAACQALEARLGGQIGVFALDTGSQARL-AYRADQRFAMCSTFKLLLAAAVLARID -AGQLRPDQRLRYGPRDLVPHAPVTGALLEGGLTVAALCEAILVHSDNPAANLLLPLVGGP -PGLTRFAREQGDVVTRLDRIEPALNSNEPGDPRDSSTPEAFVGLLDRI-LGSVLSDELRQ -QLLVWMNASETGLRRLRAGAPKDWPAADKTGTGARGAVNDVAVFFPPDRAPLLMAVFMSG -SSQPQADLEAAHAELATRA---- ->[subseq from] Beta-lactamase n=1 Tax=Thalassospira sp. TaxID=1912094 RepID=A0A2E3QB97_9PROT ---ELAYTVTQIENRLDARVGIVLLNTATEETW-SHRPHERFLMNSTVKVPICGAILAQSD -KGALSLSEALPIREADLLSYAPVTSKRVGENMIISDLCLAALDMSDNTASNLLLKRLGGP -DAVTNMFRNTGDTVSRLDRFEPDLNTFVPGDPRDTTTPAAMAATLRKLFLEDALSPSSRV -QLADWTSRGAVTGDLLRVHAPAGWEIFDKSGSGDK-TRNIVALVKPVNEQPWIVYIFISD -ADADFSTRNAALKELSAAVM--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=A0A100WBX8_9MYCO ----LDQRIGALERRHNAVVGLSAVNLDGPGAV-SHRADESFAMCSTFKAYAAGRILQGVS -RGEFSLDATEFVDPAAVVANSPRTGPRAGTEMTLADLCQAALQVSDNTAANLLLKRLGGP -PAITAYARSIGDERTRLDRWETELNSAIPGDLRDTSTPAALAGGYRALLAGDALAPPQRS -LLEQWMRANET--SSMRAGLPQGWTTADKTGGGDYGSTNDVGIAYGPDGRRVLLAIMTRS -AADDADALRPLIGELATLV---- ->[subseq from] Class A beta-lactamase n=2 Tax=Aliivibrio fischeri TaxID=668 RepID=A0A659J292_ALIFS ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00099E87A9 ---QTAERFAKIEQKFDARIGVQAVDTGTGRQV-AYHADERFAYASTHKAFTVAAVLDKYS -VDGLD-KKKIAVKASDPVGHAPVTEANVGKKLTLRELCEAAVRQSDNGADNLLVRDLGGP -KKLDAFLEGLGDHVTEVSRYEPDLTEATPGDTRDTTTPRAFTKDLRAVILEKGLGKQERK -LLDSWMLNSPTGTKLIRAGVPDDWKVSDKSGAGRYASRSDIAVVRPPGKAPIVVSVMSKR -TEEDASYDDRLVSEAATVVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050CA91B -----EQPYSQLEARDTARLGVSALDLTSGSLQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Falsirhodobacter sp. alg1 TaxID=1472418 RepID=UPI0007869C6F -----------------------------------------------FNVLLCDAVLSRVD -AGQKPLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Streptomyces hundungensis TaxID=1077946 RepID=A0A387HSS3_9ACTN ----VADELRRLEAAHDVRIGAYAVDTVTGRAV-SYRGHETFPSLSTFKAMVCAAVLDKAR -HEPGLMERVVHWKAGEEVANSPVTAGQGEKGMTVADLCHAAITRSDNTAGNLLLHQIGGP -LGMTHYYRSLGDPISRLDRWEPELNDWKPGERRDTTTPAAMGRDLAWTSLGSALVPADRD -RLNSWLRATVTGGERIRAGLPQDWTVGDKTGTTDYGSAHDIAVAWPKSGHPVILAIYTNH -TTADAAVDNAVIAQTASALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0011D1F04C ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGQ -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDADADDALISGAARAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio kanaloae TaxID=170673 RepID=UPI0010BE33C9 -------SIAKIESRISARIGVAVYDSATDQIW-NYKGDERFPMMSTFKTLTCANLFYDHE -SEGLDLESKVGIEPDELIAWSPITKSFVGKEISLRSACAATMEMSDNTAANIVLRSTGGP -SGLTEFLRFMGDRKTRLDHIEPDLNHARPGDQRDTTTPNTMVKTLNELVYGNALSEASKA -QLKAWMMNNKVSDGMIRSILPDGWRIADRSGAGAHGSRAITAIVWSETRAPLIISISLTE -TELAIPERDTVINEIVELVFDEy ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium simiae TaxID=1784 RepID=A0A1X0XWQ8_MYCSI ----FYDRLAELERQYNAYIGLFATNVGSGCTL-AHRDDDPFAMCSTFKAYAVARVLQQVQ -HGELDLQQRIFVDPAALLPNSPVTAPQAGNAMPLAQLCAAALQHSDNAAANLLLAQIGGP -PAITDFARSIGDQRTRLDRWEIDLNTAIPGDPRDTSTPRALGSGIQRLLTGTVLGEAQRS -QLERWLRDNVT--SSMRAGLPPGWITADKTGSGDYGSTNDVGMVYGPSGQRVSLSLMTRS -QSVDADGLRPLIAEVTKSVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces xanthophaeus TaxID=67385 RepID=UPI0004CD28F3 ----LAARLAGLEREHSARLGVFARNTVTGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAREAEEYAPVTGRNLAGGMTVEALCAAAVSHSDNLAANLLLRELGGP -RAVTRFSRSLGDRTTGLERWEPELNSAEPWRTTDTTSPRAIGTAYGRLLLGGALEPADRE -RLTGWLLANTTNTDRFRAGLGPDWILADKTGGGNYGVANDVGVVRAPDGPPLVMAVLTTR -PGPQGPRDSALVAATAALLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI00097707F2 ------QSIEQIESRISARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVATLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TKLTIPERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium gadium TaxID=1794 RepID=UPI0013D6F72E ---SIEASLQGLEQRHNAAIGLFASNLLSNKTV-AHRAQDQFALCSVFKGYASARVLQMAQ -HGELSLDDRMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP -PAITAFARSIGDRQTRLDRWETELNSATPGDPRDTSTPEALGWGYRAMLEGDVLAPPQRR -LLEDWMRANQT--SSMRAGLPPDWTSADKTGSGDYGTTNDVGIAYGPDGQRVLLAIMTRS -QADDTANMRPLIGETTALV---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas putida TaxID=303 RepID=A0A1X0ZNF5_PSEPU --qQVEQDAKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLKYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI00030048C4 ---SLTQNIEAIELSNGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGINKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -RSLTQFLRAIGDDKTRLDRIEPKLNEAKNGDKRDTTTPVAMSETLNTLLFGNTLNPQDKQ -TLKSWMMNNKVSDPLLRSILPSDWSIADRSGAGGFGSRGITAAVWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D107959 -------------------------------------------ICSTSKVIAVAPVLNKSE -TEPNLLNQRVENKKSVLINYKPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4R8J419_9MYCO --------LEALERANGTVIGVFGVNLETGRTV-AHRAQDTFAMCSTFKAYLAAHVLQLVG -RGERSLEQRLPVTAADIKPNSPRTEPRVGGDMTIAELCQAILQVSDNAAANILLGNIGGP -PAVTAFARSIGDPRSRLDRFEIELNSAVPGDPRDTSTPEALAGGFRAFLAGDVLAPPQRQ -LLGDWMRANET--SSMRAGLPVGWTTADKTGSGDYGTTNDVGIAYGPKGQRVLLAVMTRS -AAPDAENNRPLVGEVTATVF--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. WY10 TaxID=1920667 RepID=A0A1J0U730_9MYCO ----VDQRIAALEKRHNALVGLYAQNLESKVEL-AHRDGDLFAMCSTFKAYLSARVLQKAQ -AGELRLTDTVVVEPAELKPNSPRTEPNAGKPMTLSDLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDDRSRLDRWETELNSALPGDPRDTSTPRALGGGIARVLTGDVLDTTHRT -QLDDWMRANTT--SSMRGGLPPDWTTADKTGSGDYASTNDVGIAFGPNGERILLAIMTRT -QSDDAEPLRPLIAEVAALA---- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D99583 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-EYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPVTEPLVDHMITTKKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGDDKTRLDRIEPELNEAKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDIAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=4 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A1A0M3J5_9MYCO -------NFADLEDRYQALIGVYAVDLESSATV-EHRADERFAMCSTFKAYAAARILQMAT -AGKANLDAMVPITAGDIVVNSPVLSEAVGARMALREICAAALSQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPALNEAAPGDLRDTTTPRALCGGYRAILAGDALSGAAQF -QLRRWMEETATSTRRFRAGLPEGWTSADKTGGGDYGSTNDAGMLIGPKRERVMLTVLVRT -RTRDAGPFNEAIAESVRSVL--- ->[subseq from] Beta-lactamase GES-5 n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0X9L5U5_9BACT ----FKTDLEKLEREKAAQIGVAIVDPQGQIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA -PKLSAEQRDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora sp. OK780 TaxID=1882771 RepID=A0A2N0K2P9_9ACTN ------AGLEQLEREHAARLGVFALNPATGRTV-LYRADESFPLCSVFKGVAAAAVLRDLD -RDGEALARRIHYTRADVDAYTPDTGRNLAQGMTVEQLCAAAVGHSDNLAGNLLLRELGGP -TAITRFCRSIGDGRTRLDRWEPDLNSAEPWRTTDITSPRAIGTTYARLLLGDVLPPRDRQ -RLTGWLIANTTNTARFRAGLPADWILADKTGGGNYGVANDVGVVRPPDGPPLVMAVLTTT -LAAAGPSDNVLVQRTAELLA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-2254-4 TaxID=2022492 RepID=A0A260MPN7_9NOCA ---------LDLEARDTARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGELQLSDTRTITAADKVPESAVD-WEPGSVVTIADLAAAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTEASRM -QLLEWMANTQTSDARFRAALPAGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT -TSEDSPAMNSLVADATRQVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D9E23F ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T4Q4_9PSEU ---------------------MYAVDTATGREV-AFRADERFAYASTHKVFSAGGVLQRTP ---IAELDRTVTYGKQDLVVNSPVTEKHVATGLPLRAVMDATLRYSDNTGGNLLFRELGGP -EGLNAVFRGIGDTTSHADRIEPELNDTFPGDLRDTSTPRALAVSLRAFALGDALPEDKRK -ILVDMMRANTTGDQNIRAGVP-GWAVADKTGTAAYGTRNDIGVVWPPNRAPIVVSVLTDR -PDKDAEIDNKLLADATAAAVK-- ->[subseq from] Beta-lactamase n=1 Tax=Atlantibacter hermannii TaxID=565 RepID=Q84EY4_ATLHE ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLAGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTSPPLISANRA -TLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVAIFITQ -TEASMKMANETTAEIGKQLF--- ->[subseq from] Beta-lactamase n=1 Tax=Lysobacter sp. yr284 TaxID=1761791 RepID=A0A1H3PLR7_9GAMM ---ALRERLAAIEQRSGGRLGVAVLDTADGRHW-SMRGDERFGMCSTYKLPLVAAVLHKAE -LGQIDLNARIAVPAAALVPNSPATAALARSGASVARLCEASLTVSDNTAANLLLPLVGDP -AGLNGFLRGLGDPVTQVERTPGAPLP--GGDARDVTTPDAMLATMRAVLLGDALNAASRQ -RLSDWLLAATTGPRRLRAGLPQGWRVGHKTGTSRD-SANDIAIVWPGRRAPVLIAGYFTG -ARGDDASRDAVLADAARALATHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI000E70BD9A ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Psychromonas ossibalaenae TaxID=444922 RepID=UPI00036B7459 ----LVKKIKQIENELDARVGVSIYDAGNQKSW-DYKGDLRFPLMSTFKSLACAKLLADVD -GGHISLQSSIVIKQSSLVTYSPVTQNYVDKEFTLYQACSAAMLMSDNTAANIVLESINGP -KGLTAFMRKIGDQVTSLDRIEPALNEALPGDLRDSTSPNAINHSLHKLLFGNELSEQSKK -QLKQWMTANKVADNLLRSVLPGSWQIADRSGAGGNGSRGITAVVWQDKQAPFLISIYITQ -TDASFALRNKAIVEIGNEIFN-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. NCC-Tsukiji TaxID=2185272 RepID=A0A391PG29_9MYCO -------NFADLEDRYQALIGVYAVDLESSATV-EHRADERFAMCSTFKAYAAARILQMAT -AGKANLDAMVPITAGDIVVNSPVLSEAVGARMALREICAAALSQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPALNEAAPGDLRDTTTPRALCGGYRAILAGDALSGAAQF -QLRRWMEETATSTRRFRAGLPEGWTSADKTGGGDYGSTNDAGMLIGPKRERVMLTVLVRT -RTRDAGPFNEAIAESVRSVL--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio mytili TaxID=50718 RepID=A0A0C3EDB5_9VIBR ---HLNENISNIEQQISGRIGVSIWDTQNDSHW-DYRGDERFPLTGTAKTLACATMLESMD -TGQLDKNATSKLVKENMVMWSPVMEKMTGESVRVEHACEAAMLMSDNTAANLVLSSVGGP -DAVNLFLRRVGDNTTRLDRQEPEINEAKPGDVRDTTTPNAMVNTLESLLEGKVLAYESRL -QLRIWMQDNKVSNALIRSVLPQGWSIADRSGQGGHGSRSVNAVIWKEDHKPIYITIYVTD -TELSLQARDQLVAQISQLILEPy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) TaxID=1122247 RepID=K5BK13_MYCHD ----VTTQLAELERRHAAHIGVYARNLASGRTI-AHRSGEPFAMCSTFKTYAAARVLQLVD -RGEANLEETMFVDPAAILINSPVTAERAGGVMTLSELCQAALQRSDNAAANLLLHRIGGP -PAITAFARGIGDDRTRLDRWEPELNAAVPGDPRDTSTPEALAGGYRALLDGEVLSPLRRG -LLDAWMRANQT--SSMRAGFPPGWTSADKTGSGDYASTNDVGIAYGPAGERLLLAFMARS -ARPDAEGLRPLIGELAALIV--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1245805.9 TaxID=1856862 RepID=A0A1A3C6T4_9MYCO -----YKRFADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG -ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP -AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSQVDTSTPKDMATSVQALTVGDALAPPQRA -QLLGWMRDNTVGYKRIRAGAPLGWLVADKTGSGAYGIANDIGIVASPYCKPIVLAIYTVQ -NRRDATAREDIVATATGAILGQf ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea candida TaxID=359159 RepID=UPI000A00CFC6 ---RVTRELRALEASFQGRIGAYAIDTATGRTV-GYRSGERFPLLSTFKAPLCAAALHRAR -AEPGLMDKVVTWTTGDLKRNSPTTEKHVEDGLSVSRLCEAAITESDNTAANMVLKQIGGP -AGLTRYFRSLKDPVSRLDRWETELNDWTARERRDTTTPAAAARDLRVLTSGDALHAKDRK -RFNAWLIANKTGDARIRAGLPKTWTIGDKTGTNGIGGANDIAVAWPSSQAPIILAVYTNR -EV--AAADDAAVAKTATILA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=G8HDC7_9BACT ---------------LGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPDTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAG--------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6VG55_SPHSX ------ANLQALESIAGGRLGFALLDTGTGKIM-GHRLDERFGLCSTFKLPLAALVLRAAD -KGELKLDQLIPISKADLVPHAPDTASKVGQGMTIKELARAAQVSSDNVAANLLIKKLGGP -AGVTKRLRALGDSVTRLDRMEPELNRVIGDDPRDTSSPRAMAETVALLMTGNHLSPASQA -QLKRWMIETQTGKRRLRAVAPPGWTAGDKTGTGVRNRVNDVAIFWPPKGAPLVAVAFYEA -PGTTRPQDENVLVQAMQI----- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C5C786 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPIAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849) TaxID=1122247 RepID=A0A3P3ZYS9_MYCHD ----VTTQLAELERRHAAHIGVYARNLASGRTI-AHRSGEPFAMCSTFKTYAAARVLQLVD -RGEANLEETMFVDPAAILINSPVTAERAGGVMTLSELCQAALQRSDNAAANLLLHRIGGP -PAITAFARGIGDDRTRLDRWEPELNAAVPGDPRDTSTPEALAGGYRALLDGEVLSPLRRG -LLDAWMRANQT--SSMRAGFPPGWTSADKTGSGDYASTNDVGIAYGPAGERLLLAFMARS -ARPDAEGLRPLIGELAALIV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A419ZHR4_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001365DBA4 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVAETRVGGTMTLRELAEAAMTRSDNTAANLLLEAIGGP -AELDTALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDVDERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 05-2255-1e TaxID=2022495 RepID=A0A260LLR8_9NOCA -----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium tusciae TaxID=75922 RepID=UPI000D1D1342 ---SIEASLQGLEQRHNAAIGLFASNLVSDKTV-AHRAQDQFALCSVFKGYASARVLQMAQ -HGELSLDDRMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP -QAITAFARSIGDRQTRLDRWETELNSAIPGDPRDTSTPESLGVGYRAMLEGDVLAPPQRR -LLEDWMRANQT--SSMRAGFPPDWTSADKTGSGDYGTTNDVGVAYGPDGQRVLLALMTRS -QADDAENMRPLIGEITALVL--- ->[subseq from] Beta-lactamase n=1 Tax=Marinobacter subterrani TaxID=1658765 RepID=A0A0J7M4U6_9ALTE ----------------------ALMNCSTGAVA-SHRGDERFLFNSTGKLFIAAAVLAQVD -RGDAALDLRLVVSESDLGGWTPITEKHLGEPMTVAELCQAVVAWSDNAAANVLVRFVGGP -EAVTAFLRSIGDDVTRLDRYEPELNEDHEGDKRDTTTPLAMMKTLQRLLLGEALSPSSRH -QLAAWMIEGKTGDARLRAGMPSSWLIGEKTGTNGVGNANDIGIAWPADRGAVVAVAYTFG -PKASKEQRDDVIAMIGAMA---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium poriferae TaxID=39694 RepID=UPI0013D5004A ------PRIEALERREGIIVGLHAVDLPTGRRL-AHRAKDRFAMCSTFKGYAAAAVLSRVD -RGLLALTDTVTIAPAELVTYSPVTEPRLGQPMTLAELCQAAVQQSDNSAANALLRVLGGP -PAITEFARSIGDEVSRLDRWETALNSAVPGDLRDTSTPVALGTGYRALLAGDALGGSSRQ -TLQDWMQANET--SSMRAGLP-GWSTADKTGSGDFGTANDVGIAYGPQGQQLLLSIMTRS -AGPEAPSRRDLIGELAALVA--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia unamae TaxID=219649 RepID=A0A328X5A9_9BURK -----ESPFAAIERRSGGRLGVFAVDTGSGATL-AWRADERFLMCSTFKGMLAAQILARVD -AGHERLDREVRYTERDLIFTSPVTKANLAQGMTVGALCKAAVEVSDNTAAILLMRGAGGP -AALTRFMRDIGDDVTRSDRYEPASNQR--DGELDTTTPHAIVESARKILLGDVLGAQPRQ -QLEDWMIASTPGRNRIRASLPPDWRAGDRPGTSVEAETNDYAIVRPPGRAPLVVATYFDA -PGLDMARREAVLREAGAAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia grenadensis TaxID=931537 RepID=UPI0009FFAD75 ---DLSNTLMALQAKYNVLFGIAAVDTRGGRTF-EWNADDRFALCSTFKVYAVAAILRLAE -RKELDLNDKVAITRQDIVMSSPVVSDHVGELMSYYELSRAALVRSDNTAANLLLRRLGGP -RAVTEFARTVNDSQTRLDRWEPELNEARAGDPRDTGTASALAAGYRKLVLGDGLSTEYRR -MLTSWMRSSVTSRQRLRAGLPVGWVAADRTGSGAYGTANDAGVVWSPAGTSLVLVVFSRS -TTPMAAGADAAVADATAAVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis ganjiahuensis TaxID=239984 RepID=UPI000476E528 -----AAEFEALEEEYGSQLGVYALDTGSGAEV-AFQEGERFAFASTFKALLAGVVLSENS ---LEEMERVVTFDEGVLVSHSPVVEENLDSGMSLLELCDATVRFSDNAAANLLLEEIGGP -EGFTESLGETGDDVTILERYEVEMSSAVPGEVRDTSTPKAMAGSLEAFALGDVLPEDRRE -VLVDLMVRNVTGDDLIRAGVPEGWVVGDKTGNGGYGTRNDIAVLWPEEGDPIVLAVMSSV -GVEDAEHDDALIAEATEVVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000F04ADC5 -----------------------------------------------FKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLPSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora cheerisanensis KCTC 2395 TaxID=1348663 RepID=A0A066YSA8_9ACTN ---------------------MYVLDTGSGREV-AHRADERFAFASTSKALVGGALLRRAS ---DADLERVVTYRQQDVLAWAPVTSQHLATGMKLRDLLAASLDHSDNTAANLVMAEVGGP -AAVQQALRDLGDSTTDVSRTEPALNEAVPGDRRDTSTPRVLADDLRQYLLGDVLPPARRQ -LLTDLMLANTTGGPYIRAGVPAGWQVADRTGNGGYGTRNDLAVVWPGGGKPLVVAVLSDR -SRPDAPSNDTLLAEATEAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium tusciae TaxID=75922 RepID=A0A1X0JJZ3_9MYCO ---SIEASLQGLEQRHNAAIGLFASNLVSDKTV-AHRAQDQFALCSVFKGYASARVLQMAQ -HGELSLDDRMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP -QAITAFARSIGDRQTRLDRWETELNSAIPGDPRDTSTPESLGVGYRAMLEGDVLAPPQRR -LLEDWMRANQT--SSMRAGFPPDWTSADKTGSGDYGTTNDVGVAYGPDGQRVLLALMTRS -QADDAENMRPLIGEITALVL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-221-2 TaxID=2022514 RepID=A0A260BSG7_9NOCA -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGKKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 1R11 TaxID=2559614 RepID=A0A4Y8YZF9_9NOCA -----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRE -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI00110DD28F ----VDERLREIEDRYAVRLGVVAQSPGTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. Soil538 TaxID=1736391 RepID=A0A0Q9JRW0_9MYCO ------DRIEALGRRHNAEIGLYATDLESGREI-AVRDGDSYALCSTFKAYASAAILQRAQ -HGRLGLTDAVRVERADIQPHSPVTEPRVGATMTLAELCQAALQQSDNAAGNLLLRTLGGP -PAITEFARGAGDDRSRLDRWETALNSAVPGDPRDTGTPRALGTGFRAVLTGDVLDAAHRQ -QLENWMRANET--SSMRAGLPDGWSTADKTGSGGYGTTNDVGIAYGPQGQRWLLSIMTRA -AGPDAPNLRPLIGEIASVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Aeromicrobium erythreum TaxID=2041 RepID=A0A0U4D7H5_9ACTN ----FSADFADLEQEYDARLGVYAIDTGTGQVV-EHRAGERFAYASTIKAIAVGALMHEKP ---RSVLDQTVQISEDDLVDFSPQVEKALEAGLTVREVADAAVRYSDNTAGNLLFDLLGGP -EELQGVLREIGDRTTKVSRIEPDLNEATPGDDRDTTTPEALATDLRRLTLKDVNDGYARA -FLTDLMVRNTTGDDLIRAGVPDTWEVADKTGAAKYGTRNDIAILRRAEGAPIVIAIMSSK -DDQDAEADDDLVADATRVAVAGf ->[subseq from] Beta-lactamase n=2 Tax=Marinobacter TaxID=2742 RepID=A0A1M2URI1_MARHY --qQVEQDAKVIEASLSAHIGISVLDTQTGESW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGEINPKSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase CARB-4 n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=BLC4_PSEAI --qQVEQDAKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. JG-3 TaxID=1305835 RepID=UPI0004872312 -----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTRASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SII5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWV----------------------------------- ------------------------ ->[subseq from] Beta-lactamase GES-2 n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q93F76_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMNDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 1245805.9 TaxID=1856862 RepID=UPI0009ED2FF8 ------KRFADLEREFDGKIGVYAVDTNNGELI-AHRADERFPLQSTIKLLGVAALLKRGG -ADSNLLQEQVHYSERDLTTWSPVTRKNIAGGMTLEALAEAAISDSDNTAMNLITKALGGP -AEVERFAHSVGNQKYNVEHYEGQLNSD-PHSQVDTSTPKDMATSVQALTVGDALAPPQRA -QLLGWMRDNTVGYKRIRAGAPLGWLVADKTGSGAYGIANDIGIVASPYCKPIVLAIYTVQ -NRRDATAREDIVATATGAILGQf ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4X6F6_9PROT -------RFAAIEARIGGRVGVAAWNTATNAWL-GHRQHERFAMCSTFKWALAAHMLWIGQ -RQPDFLGSRVLYREADLLSYAPVTRERFGSGMTVEYLCEAAVGLSDNTAANLLLEAAMGP -EGFTRFLRANGDAVTRLDRYEIELNDVPPGDERDTTTPEAMARTLKRFLVDDVLTPAHRE -KLIGWMVDSPTGLQRLRAGFPADWRVGDKTGTWNHNATNDVAIAWPPNRAPIVVAAYLSA -STADVAARNAAHAEIARIITEAw ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium agri TaxID=36811 RepID=A0A2A7MYU9_MYCAG -----HQRIEALQRQHNTKIGVYAVDLASGRTV-SHLDGEMFAMCSTFKGYAAARVLQMVQ -NGELTLDRQVYVDPKAALPNSPRTAPNSGGQMSLADLCAAAVQVSDNAAGNLLLQTIGGP -SAITHFARSIGDERTRLDRWEIELNSATPGDPRDTSTPRALGGGYRALLTGDALAPPQRQ -QLEDWMRANET--SSIRPALPEGWTTADKTGNGDYASTNDVGIAYGPQGERLLLAIMTRT -QTPDAPNNRPLIGEVTKALV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 15-2388-1-1a TaxID=2023142 RepID=A0A260RZH6_9NOCA ----AEQNYLDLEDRDTARLGVSAVHLDSDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGTLQLSDTRTITAEDKVPESAVD-WAPGSIVTIADLASAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE -QLLAWMADTQTSDARFRAALPAGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVILSAT -TSEDSPAMNSLVADATRQVVQQ- ->[subseq from] PSE-1 n=1 Tax=Gallibacterium anatis TaxID=750 RepID=A0A161HRT0_9PAST --nRLNKMLKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPSTSTFKTIACAKLLYDAE -QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLKYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia aspalathi TaxID=1324617 RepID=A0A1I7E3E4_9BURK -------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLARLVKYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSVGGP -AALTQFVRGLGDTVTRSDRYEPESNKN--SGVLDTTTPRSITNSASKILLGNVLSPQSRT -QLENWMIACKPGLNRLRAALPPDWVAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA -PALDMPAREAVLREVGAVFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio pectenicida TaxID=62763 RepID=A0A427U5F7_9VIBR --------IEAVSTSLGARVGVFVSNANTNQQW-HYNGNQRFPTASTFKVLACAAALDKGA ------LSTAVKITEKDLVEYSPVTEKYINNTMTYNQLCHATITTSDNTAGNLILRYIGGP -EGLTQFLRGTGDNVTLMSRWEPELNQGTPGDKRDTTTPHAINRTLGILLFGDVLSQSKQQ -KLLQWMKQDQVADDLLRSVLPKTWQIGDKTGAGGHGSRGIIAVLIPPNSEPVLVSIYLTE -SQTTIKQLNKAIATIGSAIIK-- ->[subseq from] Class A beta-lactamase GES-41 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A4V1E803_PSEAI ----FRTDLEKLEREKAAEIGVAIVDPQGQIVA-GHRIEQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGRDMIVEWSPAAERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTPTSTH -TIERWLIGNQTGDATLRAGFPKDWVIGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA -PKLSAEQRDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio alginolyticus TaxID=663 RepID=A0A2S1XWT4_VIBAL --qQVEQDAKVIEASLSAHIGISVLDTQTGESW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGEINPKSTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEIy ->[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / PAl5) TaxID=272568 RepID=A9HJJ4_GLUDA --------ISDYENGTGGHIGLYAENVKTGAKL-TWRARERFVMCSTVKASLAACVLSRVD -RGRDRLEDIIPYSASDIQDYAPVAKANLARGMSVGDMCQAAVEQSDNTCANILLARIGGP -SALTAFWRGIGDRETRLDDPEPYLNRTPPGGVRNTTTPASMATIMRSLVLGRVLSDASRA -IFTRWLVGCRTGDDRLRAGLPPHWVIGDKTGNNGRDAAGDIAVVWPERDVPIILCVYTRG -GSPTQQQFRTAFAGIARVV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI0011A62ED0 ----VDKRLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES -EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLHRIGGP -EAVTAFARSVGDEVTRLDRWEPELNEAARGDERDTTTAAGLAHGFREVLLGSGLPDPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPMVLAILSDS -TTGDP------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia oxyphila TaxID=614212 RepID=UPI00048838FD ---AAESPFADLERRNGGRLGVFAIDTGSGRTL-AWRADERFLMCSTFKGLLAAQILARID -AGQERADRQVRYTEQDLIFTSPVTKAHVAHGMTVGALCEAAVEVSDNTAAILLMRSAGGP -EGLTQFVRGLGDSVTRSDRYEPHSNQY--SGALDTTTPRAIAQSARKILLGNVLSMQSRQ -QLEDWMIASTPGRARIRAALPADWRAGDRPGTSVERETNDYTIVRPPGRAPLVVAAYYDA -PGRDMARREDVLRDAG------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 06-1460-1B TaxID=2022501 RepID=UPI000B9ACAC6 -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI000A1C9182 ----VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES -EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLHRIGGP -EAVTAFARSVGDEVTRLDRWEPELNEAARGDERDTTTAAGLAHGFREVLLGSGLPDPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPMVLAILSDS -TTGDP------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D9ACBD ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLIALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A8HNR5_KLEPN ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKPAA---------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZZ2_9BACT -------PFLAIERRSGGQIGVAAFNVRTGAAL-TYRSDERFAMCSTFKWLLGGLILQRVD -RGIEDLERRLPFDSSDLVFHSPVTEAHADGRMSVGDLCEATIKTSDNTAANILMETLGGP -SGFTQSLREMGDRVTRLDRLEPYLNENAPGDLRDTTTPMAMANLMREILFGTRLSDGSKD -MLHDWMIGASTGLDRLRAGFPEGWRGGDKTGTSSNRANNDVGFALPPAGDAIIIASYTNV -PDPLDGAANAVHSEIARHVI--- ->[subseq from] Beta-lactamase n=1 Tax=Psychromonas sp. Urea-02u-13 TaxID=2058326 RepID=A0A2N1A8C2_9GAMM ----LTEKIKSVEKKLGARIGVAVYDTQSKALW-SYKGDTRFPLMSTFKTLACAKLLADAE -SGIVDINSTTMIDADSLITWSPVTEKRVGETMSLKQACTATMVMSDNTAANIVLAGIDGP -SGLTKFMRAIGDDVTRLDRIEPYLGEAIDGDPRDSSTPNAMVASLNRLLFAGVLSTEGKV -QLKQWMMDNKVSDALLRSVLPQGWSIADRSGAGGYGSRGITAVVWSEQRPALIISIYLTQ -TTASFAQRNDTIATIGKHIFTVy ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia aspalathi TaxID=1324617 RepID=UPI000B87BFDC -------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLARLVKYTGKDLIFTSPVTKAHVAEGMSVGALCQAIVEVSDNTAAVLLMRSVGGP -AALTQFVRGLGDTVTRSDRYEPESNKN--SGVLDTTTPRSITNSASKILLGNVLSPQSRT -QLENWMIACKPGLNRLRAALPPDWVAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA -PALDMPAREAVLREVGAVFV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. (strain SPB074) TaxID=465543 RepID=B5GAH4_STRSH -----AAEFTALERAYGAHLGVHAVDTGSGREV-AWHADTRFPYNSTFKALLCGAVLKKHG ---TGAMDHVLRYSREDLVANSPVTEKHVATGMSRDALCDAAIRYSDNTAANVLLTELGGP -RALGALVRETGDRLTRMERVEPLLSRWTPGETRDTTTPRRLTADLRAYTLGDVLTTPRRQ -RLNGWLSRNTTGDATIRAGVPKGWKVADKTGTGSHGARGDIAVIRPPGRAPLVLTLLSYR -EERTAEADDRLLAEATRVVVR-- ->[subseq from] Beta-lactamase GES-13 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=D1MIX9_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMNDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J3 TaxID=903528 RepID=A0A1X7KG93_RHORH ----VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES -EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLHRIGGP -EAVTAFARSVGDEVTRLDRWEPELNEAARGDERDTTTAAGLAHGFREVLLGSGLPDPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPMVLAILSDS -TTGDP------------------ ->[subseq from] Beta-lactamase n=1 Tax=Henriciella sp. TaxID=1968823 RepID=A0A2D8YA11_9RHOB --------IEALELGHEGRFGVAAVTSGGEDLV-SHRADERFAMCSTFKWLMAGLVLQEVD -SGRETLERRVPIAGEDLVFHSPVTSQHVGAQLPVSQLCAATIGTSDNTAANLLLAGLGGP -DGFTQRLRASGDMVTRLDRMEPALNENEPGDPRDTTTPRAMARNLDRFLFGSQLSAPSRD -MLRTWMIAADTGLDRLRAGLPAGWTSGDKTGTSSNGANNDVAFSIPPDAKPLIIASYLNL -PDPVSPEANALHAKIAGLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI00132EF12E ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGPGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium moriokaense TaxID=39691 RepID=A0A370CTK5_9MYCO ---AVNDRIEALQRQHSAKIGVYAVDLASGRTL-SHLDNEPFAMCSTFKVYAAARVLQMVQ -NKALDLNRQVFVDPAQSALNSPRTAPNSGGWMSLADLCAAAVQVSDNGAGNLVLQTIGGP -GAVTDFARSIGDDRTRLDRWEIELNSAAPGDPRDTSTPRALGEGYRSVLAGTVLAPPQRG -QLEDWMRANQT--SAVRGGLPAGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAIMTRS -RTDDAPNNRQLISELAQAVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Telmatospirillum sp. TaxID=2079197 RepID=A0A6A8QMB2_9PROT ---TFEARLKDLEARSGGRLGVALLDSATGQIV-GNRLDERFALCSTVKALVVAFVLSRVD -RDEESLERRIVFTERDLVIPFKATRPHVGPEMTVGALCEAAITVSDSTAANLLLQSVGGP -AALTAHLRSLGDPVTRLDHVELALNIVKPGETHDTTTPRAMAETMRRLLLGDALSDASRG -RLTNWMVAATAATRRLRAGLPAGWRIANKPGTWEGISTNDAGVIWPPGRAPVVVSAYLGE -APGSTETQEGVLAGVARIVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. michiganensis TaxID=33013 RepID=A0A251Y021_CLAMM ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAMPIEAADILSYAPVTETRVGGSMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTCATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVIAVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium neglectum TaxID=242737 RepID=UPI000BFEB732 ---SVDASIQGLEHQHNAFIGIFATNLVSGKTV-AHRAQDPFAMCSTFKGYASARVLQMAQ -HGELSLDDTMFVDPASILPNSPLTEPRAGGEMTLAELCQAALQQSDNAAANILLTRIGGP -PSITAFARSIGDERSRLDRWEIELNSAIPGDLRDTSTPEALGGGYRALLDGDVLAPPQRG -LLENWMRANQT--SSMRAGLPPGWTTADKTGSGDYGSTNDVGIAYGPDGQRVLLAILTRS -QANDAENMRPLIGEVTALVM--- ->[subseq from] Class A beta-lactamase n=1 Tax=Gammaproteobacteria bacterium CG_4_9_14_3_um_filter_38_9 TaxID=1974022 RepID=A0A2M8A1Z2_9GAMM ---SVSQKLHQLEIKDHVEIGLSAIETYNNTQI-NYHANQRFPMDSTSKLMTVSAILKKSE -GDPTLLKQKIFFTIKEVKKYAPITSKHIQSGMTVSDLCAAALKYSDNAAVNQLMKILGGP -NKVTQFARSIGDNQFLLTRWEPELNSAIPYDKRDTTAPSAMAESVQKLVLGNALRKSQRQ -LLQEWLKHCKTGNHRIRSGVPAHFIVADKTGTGGYGSIGDIGVVWRPHASPIVLAVYVRQ -NEKNAHTSDKVIAQATKITIN-- ->[subseq from] Beta-lactamase n=1 Tax=Zobellella taiwanensis TaxID=347535 RepID=A0A2P7QX08_9GAMM --qQVEQDAKVIEASLSAHIGISVLDTQTGESW-DYNGNQRFPLTSTFKTIACAKLLYDTE -QGEINPKSTVEIKEADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDSQK -KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSSIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI001427ECEC -----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVITIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase class A/beta-lactamase class A CARB-5 n=1 Tax=Pseudomonas guariconensis TaxID=1288410 RepID=A0A1G6K5N6_9PSED ----IQEAAPQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- ---QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP -KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA -QLTEWLSNNEVGGPLLRAAIPNDWQIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKD -TEASLDERNAAIAAIGRAMVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=A0A260U0X5_RHOFA -----EQPYSQLEARDTARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVITIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A494QX91_CARML --kAIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVGDYf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas TaxID=286 RepID=UPI0003A8DD53 -----QEAALQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- ---QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP -KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA -QLTEWLSNNEVGGPLLRAAIPNDWRIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKD -TEASLDERNAAIAAIGRAMVK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UWS2_9BACT ------DRFTSIEARIGGHLGVAAIETASGKRI-DYRPDERFPMCSTFKFLAVAAVLKRVD -EKQERLDHFVPYGQREILEYAPVIKEHVKEGMILGALCEAAIEQSDNTAGNLLLDAIEGP -AGLTNFVRSLGDKMTRLDRKEPELNSAIPGDERDTTTPGSMLADMMRLLVGDVLSPSSRR -QLEDWLQKNKTGAAMIRAGAPTTWIIGDKTGRGANGATNDIAIMHP-------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium llatzerense TaxID=280871 RepID=A0A0D1JSY8_9MYCO -------RFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMAK -AGQANLDAMVPITAADIVVNSPVLSPAVGTRMELREICAAALTQSDNAAGNIMLRTIGGP -SALTAFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALSGAGQF -QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. ANT_H53B TaxID=2597357 RepID=UPI0011EDA1C8 ------QVYLDFEARDNARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGALQLSDTRTITAADKVPESAVD-WTPGSVVSIADLAAAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE -QLLAWMADTQTSDARFRAALPAGWTSADKTGTGSYGVSNDAGLLLGPDGQRFLVVVLSAT -TSEDSPAMNSLVADATRQVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus sp. MO-4 TaxID=2672568 RepID=UPI0013DD82B1 ----LRRAIAGIERSAGGPIGVALIDTGNGARF-SHRADQRFPLCSTFKLLLAARLLDGAR -RGQWRMDERLPVRREDMLFNAPFTEKRIGGSASLTEMAEAMVVQSDNPAANLALARVGGP -AALTIWLREIGDTVTRLDRNEPEMNNEVPGDPRDTTTPSAMLATCRRLVAGPLLPAPARA -QLLGWMAASRTADTMFRAALPPGWREANKTGAGSWHARNIVSIITPPGRQPIWVAAYLFA -AKAELEERNRQFVPLGRAIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0007C5C7B0 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDIKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 05-2254-6 TaxID=2022489 RepID=UPI000B9B02FA ------QVYLDFEARDTARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGELQLSDTRTITAADKVPESAVD-WEPGSVVTIADLAAAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIHGDPRDTTTPNSMAAGYRTLLDGDVLTEASRD -QLLAWMADTQTSDARFRAGIPDGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT -TSEDSPAMNSLVADATRQVVEQ- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G9A0_9SPHN --------IAAYEAATGGHVGVYARNVATGRTI-AWRPDERMVMCSTFKASLAACVLARVD -RGRARLADPLRLDAADMQDHAPVARANLARGMSVGEMCRAVVEQSDNSCANILLREIGGP -AGMTRFWRALGDDVTRLDDVEPVLNRTPPGGIRSTTTARSMATILETLTLGPVLSPGSRA -TLVAWLKGCRTGDNRLRAGLPDGWAVGDKTGNNGRDAAGDIALVWPRPGVPIVVSVYTRG -GSPVEAQFAALFAGIGRAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces luteoverticillatus TaxID=66425 RepID=A0A3Q9FZH9_STRLT ---EITRRLGQWEREHSVRIGVYARDTATGRTV-EYGADDAFPMCSVFKTLAAAAVLRQDR --HGELLGKRIHYTEQFLKDYADSTKNNLANGMTVAELCAAAVSESDNAAANLLLRELGGP -TAITRFCRSLGDDTTRLDRWEPQLNSAEPDRETDITTPGAIGRTYERLVLGHALTGPDRE -RLTGWLIANTTNKQRFGKGLP-GWTLADKTGGGDYGVANDVGVVWPPHRRPIVLAVLTTA -LSATAPTNNALVADIAALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009EB279B ----FQQGLAQVEAASRGRLGVALLDVGSGQAA-GYRADERFLMLSSFKTLSAAYVLARAD -RGEDQLSRRIPITDADVREYSPVTRLHVGPRMTLAELCEATITTSDNAAVNLMHKSYGGP -QALTRYLRSLGDTVTRHDRYEPELNRPHPSEPQDTTTPQAMARTLDTLLFGDALKPQSRQ -QLQSWLLANTTGGKRLRAGMPADWKIGEKTGTYSKVGCNDAGFAQPPGAAPIIIA----- ------------------------ ->[subseq from] BlaVCC-1 n=2 Tax=Vibrio cholerae TaxID=666 RepID=A0A0U3IB62_VIBCL ---EHNKNMADIEAAFEGRVGVYAINTGSGKAY-SYRANERFPLCSSFKAFLAAAVLKMDQ -DSPGVLLEKVNYHNRTMEPHSPITEKFQSQGMAVGELAAATLQYSDNGAANLLMEKIKGP -EGMTQFMNSIGDTKFRLDRWELDLNSAIPGDERDTSTPKAVAESLNKLISNTVLDNYHQE -IFKKWMIGNTTGDNRIRAAVPDGWVVGDKTGTCGYGTANDHAFILQGNNAPLILSIYTTR -KGEHMKHDDEVIAKAARIAIE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas guariconensis TaxID=1288410 RepID=A0A2N5QE25_9PSED -----QEAALQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- ---QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP -KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA -QLTEWLSNNEVGGPLLRAAIPNDWQIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKD -TEASLDERNAAIAAIGRAMVK-- ->[subseq from] RCP family class A beta-lactamase n=1 Tax=Gemmobacter sp. HB-1 TaxID=2652247 RepID=UPI00124F0C76 --eALSETVARIEEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAILARWD -AGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGHLGGP -EAVTQFFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSPEARG -KLAEWMRHGGVTGALLRAEVEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATMFISD -TDAEFEVRNEALKDLGRAVV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UHH7_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGW------------------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=UPI000782EA90 ---------SSYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD -QGKESLETVVPYTASDLGDYAPVAKANVAAGLSVRAMCQAAVEWSDNVCANLLLARVGGP -AALTRFWRSLGDRQTRLDDWEPVLNRTPQGGLRNTTTPEAMAWILEHLVFGHALSGASCS -LLTGWMKNCQTGKGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG -GQPDEKQFFEVFSEIGRIAAE-- ->[subseq from] Beta-lactamase n=3 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=K8ENU7_CARML --kAIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVGDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas sp. HMSC08G10 TaxID=1581141 RepID=A0A1F1Q9W4_9PSED -----QAAALQIERTLKATVGYSIHDTGTGRSW-QYRADERFPMASTVKLLLCSTLLNEG- ---QALMTRSVPIHSQDILAYAPVTKDLVGTHVPAAKLCAITLKTSDNTAANAVFEVLGGP -KVVTAFVRGLGDQTTRSDRNEPSLNEVMPGDERDTTTPRAMANTVKALLLGTALDTPSRA -QLTEWLSNNEVGGPLLRAAIPNDWRIADRTGSGSFGARGIAAVLWPPRGEAIVATIYLKE -TEASLDERNAAIAAIGRAMVK-- ->[subseq from] Beta-lactamase n=1 Tax=Rhizobium sp. S-62 TaxID=2653123 RepID=A0A5J4M6K7_9RHIZ -----------IETKSGGELGVAVLDTGTNQVV-GHRLDERFALCSTFKVLAIAFVLARVD -QGKEQLDRRVDFSEQDLVLPYKATKPHVGAEMTIDELCKAAAIYSDSTAANLLLASFGGP -AELTDYLRSIGDNVTRVDNVEPKLNIVKPGELHDTTSPRAMAETMKRIILGDMLSPRSRG -LLTDWLVNGQDATQRLRKGVPAGWRIANKPGTWKGISTNDVGVIWPPHRPPVVVAAYLSH -APGSIESQEAVLADVARRVCD-- ->[subseq from] Beta-lactamase n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=A0A562TAZ0_9RHOB ---ALENKLNELEQREDARIGLALIDTQTGTEF-SFRGTERFALNSTFKAFACGALLSQAE -AGGPNLSESRSIREDDLVSWSPVTKNRVGTDITLRESCEATMVYSDNTAANIVLQALGGP -AAFTAFMRDIGDRSTRLDRMEPDLNVVPAGTDQDTTTPEAAANSLKELITGELLAAPSKA -QLIAWLSANTTAKHMLRPHLPEGWTIGDRSGASRDRKRSVIAVIYPPDQAPVFVAVYLHL -EKAGIAERDAIIAELGKSIFD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. CB01881 TaxID=2078691 RepID=A0A652NT58_9ACTN ---AVARELAALEREHAARLGVFARNTATGATV-LYRADERFPLCSVFKPLAAAAVLRDVD -RNGGSLAKRIHYTAQEVKDYGPVTEENLANGMTIEALCAAAIGESDNLAGNLLLRELGGP -TAVTRFCRSTGDGRTRLDRWEPDLNSAEPWRTTDSTSPRAIGSTFGRLLLGDVLAPRDRE -RLTGWLLANTTNTERFRKGLPKDWTLADKTGTASYGVANDVGVVRPPDGPPIVLAVLTTT -HAATGPSDSALVARTAELL---- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D9CC6B ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIIPWSPITEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAIGNTKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNPQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEIGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingorhabdus wooponensis TaxID=940136 RepID=A0A3R8R3J6_9SPHN ----ANAALAALEARAGGRLGALVLDTASGRMT-GHHYDDAFAMCSTFKLALAAAVLQQAD -QGRLKLDTVLPYSQADMVPHAPVTGPNLAKGMRIIDLAEAAQKTSDNVAANLLMKHLGGP -AAITAIFRSWGDDVTRLDRYEPDVNNVPPGEVRDTTTPRAFAWMMARLLTDDILQPSSRD -LLTQWMVDTATGMKRIRGGLPASWKSGDKTGTANNNKTNDVAIFWPPARPPVIVTAFYEA -DGQTRDSDQAVLAEIGKIAAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Falsirhodobacter deserti TaxID=1365611 RepID=UPI000FE3FA1F ------ATITRWETQLSARIGVALHDSGSGQSW-GYREDERFPLNSTVKVPICGGILALAD -QDQLELEEGVTITEGDILSYAPVTREHVGEQLTVSDLCFAALDRSDNTAANLLIRRAGGV -GALTEFLRGIGDDVTRLDRMEPELNSYDTGELRDTTTPAAMIATLQRLAQGDALQPASQE -RLVGWMQPGGVTGPLLRPSIPEGWDIADKSGAGDN-SRSIVAMITPPGGAPAFLAIYIAQ -TDADLNTRNAAVAEIGAELV--- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. L-033 TaxID=2614798 RepID=A0A5N0TIZ7_9MICO ---AVSDDIAGLEAQYQARVGVSALDTASGDSV-QYRADERFGFASTIKVFAAAAMLRQIP ---EDQRDARLTWTPEEMVAYSPVAEEHLGTGMTIREAAEAAVRRSDNTAMNLVLGRIGGP -AGLDAELVQLGDTTTEAIDSEPELNRVDPGSPANTTTPAAFTAALHEVMRSDYLAPTDRA -VLIEWMSGNATGDALIRAGAPAGWEVADKSGGAG-GMRNDIAIVTPPGRAPVILTVMTAK -DDPAAAYEDELVAAVARTVLSAf ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3BDA9C ----ADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAHALGDPLDADERA -LFTGWLKATHTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRADAAPIVIAVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] class A beta-lactamase n=2 Tax=Nocardiaceae TaxID=85025 RepID=UPI000B9B8729 -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLMLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A0R2J8S9_CARML --kTIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVGDYf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI0013276CEF ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARSA -LDASLLSRRTLYRRYDLVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QSVTAFAHDSGDTSFRLDRWEPALNAATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia bryophila TaxID=420952 RepID=A0A329BY07_9BURK ----TESPIAEIERRYGGRLGVFAINPASGRTL-AYRADERFLMCSTFKGLLVAQVLARVD -AGKENLERLVRYTERDLVFTSPVTKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP -AALTRFMRDIGDSVTRSDRYEPESNQA--SGVLDTTTPRAIATSAARILLGDVLNPESRR -QLDAWMVACKPGLNRIRASLPADWLAGDRPGTSVERETNDYAIVRPPGRAPLLVAVYYDA -PGVSMELRETVLREAGHR----- ->[subseq from] Beta-lactamase n=1 Tax=Kutzneria buriramensis TaxID=1045776 RepID=A0A3E0GZ79_9PSEU ------PDLAALERKFGGRLGFYALDTASGKTV-AYRSGERFLMCSTHKVLVVGAILQLRQ -QQPGLLDRVITYDKSQVLSYAPITSQHS--GMKVAELCDAALRLSDNTADNLLIDLLQAP -QAVTAFARDLGDNVTHLDRKEPDLNDGAPGDERDTTRPPVFASDLNELTLGEGLDSAGRD -MLVNWMKSSTTGLDLVRGGLPPGWVAADKSGSGAKGEVNDVAVVWPPNRAPLVIAAYTAP -TDPKSTAGRKTIADATAIAVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia suismassiliense TaxID=2077092 RepID=UPI000D1E6CC3 ----ATARVSELESAHHARVGVFAVDTKTGVFL-GYRENERFPIGSTFKTLAVAALLREHP -LADGYFDTVIHFTADDLVKYSPVTETRVDTGMTVRELAAAAIEKSDNTATNELLKLLGGP -TSITKFVRTLGDTATSLDDWEPLSNSGDTNPEHNSTTPAALAADYRALISGDALPAPERA -QLTEWLLRSTTGLNRIRAGLPQDWKTGDKTGGGDYGLTNDAAVTWPPNSSPIVITVLSIN -TEEHAPADDPLVAQSAKAVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia autotrophica TaxID=2074 RepID=UPI0005623D00 ----AQAELADLERRAGGRLGVSALDTGSGAAL-GHRADERFLLCSTGKLLAAAAILHRFE -ADRDILERVVPYTSSVLVPNSPETGKH--TSMTVGELCHAAMTLSDNTAMNLLLGVLGGP -EKVTAFLRSAGDPVSRLDRTETALNAR--DGDLDTSTPARMAANTRLLALDDGLTPDNRD -VLVGWLKANTTGVTRIRAGLPADWVVGDKTGAGARGEINDVAVVWPPGRAPLVIAVYTEP -PDPD-ADAAPTVAEAARIVARSf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-147 TaxID=1813676 RepID=UPI0007BB9EF7 ------QVYLDFEARDNARLGVSAVDLASDSTE-SHRGDERFAFCSTFKVYAFGAVLAAVD -AGALQLSDTRTITAADKVPESAVD-WEPGSVVTIADLASAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE -QLLAWMADTQTSDARFRAGIPDGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT -TSEDSPAMNSLVSDATRQVVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. 2G TaxID=1570939 RepID=A0A1J0TK32_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Celeribacter neptunius TaxID=588602 RepID=A0A1I3K968_9RHOB ---------REIEQALAARVGVFARNIDTGAEF-SHRAGERFAMCSTFKASLAALCLQRAD -RGELDLDERLSLNGVPLLPTSPVTSQQPPSGLEIRTLCKAIVERSDNTAANLLLDRVGGP -AAVTGFFRDIGDDVSRLDRTEMALNANTPNDPRDTTTPEAMARTVERLTLGTVLSEGARQ -QLVAWMRNEQNAKDRIRAAVPGSWTVANKPGTTPNGAANDIAALWSPDGPRFVLAVYIDT -RLDSVRPSVAAIREVAQIALR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D3J1E5_KLEPN ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPXMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIA--------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=UPI0002F4DCE9 ---AAQSQLDALEKASNGRLGVAALDTASGARI-AYRSRERFPVCATYAVVAVAAMLARSA -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QAVTAFAHGSGDTSFRLDRWEPALNTAVPGDERDTSTPLAMAESLRRLLLGDVLREPERT -QLTRWMLGNTSGFAGIRAGVPSDWRVAGVGGAGGYGTTTDVAVLWPASRAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. JUb58 TaxID=2485114 RepID=A0A4R7FUM0_9BURK ---ALHKALTLIEAQSGGRLGVYALDAETGGEA-GYRSDESFPMCSTFKTLLAAHVLYLGQ -TGALDLGQQVLVTSADMVPYAPVTEKYKDQPISLLELSEAIVVLSDNVAANLLLRASGGP -EALTAWLRTLGDKATRLDRIEPLLNTAEPGDPRDTTTPRAMQATLQALLLGDVLKGYGRA -MLQQWLSDSRTGDKRVRAGLPSEWRVGGKTGAGAHSTANDCLIAWPNAAEGLIITAYLTG -GERTTAQSDEVMAKVGAAIAQ-- ->[subseq from] Class A beta-lactamase GES-40 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A3G3C179_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Dialister succinatiphilus YIT 11850 TaxID=742743 RepID=H1CXJ7_9FIRM -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTIKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=D3X610_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] GES family class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0005B38428 ----FRTDLEKLEREKAAEIGVAIVDPQGQIVA-GHRIEQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGRDMIVEWSPAAERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTPTSTH -TIERWLIGNQTGDATLRAGFPKDWVIGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA -PKLSAEQRDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1274756.6 TaxID=1834076 RepID=A0A1A3JCZ7_9MYCO ---SVDQRLDELEARDNATIGVFAADLASGRTL-TYRATDSFAMCSTFKVYAAAAMLQRVQ -RDELTLDQPLFVPPAAIVPHSPRSAPNSGGSMTVAELCAAALQVSDNGAGNVLLQTLGGP -GAVTDFARSIGDGRSRLDRWETQLNAAVPGDPRDTSTPEALGNGYRALLTGDVLEPILRQ -QLDGWMRANET--SSMRAGLPPGWTSADKSGAGDYGSTNDVGIAYGPGGQRVLLALMTRS -RAPNADSQRALIGELTALI---- ->[subseq from] class A beta-lactamase n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=UPI0012BBDE18 ---ALENKLNELEQREDARIGLALIDTQTGTEF-SFRGTERFALNSTFKAFACGALLSQAE -AGGPNLSESRSIREDDLVSWSPVTKNRVGTDITLRESCEATMVYSDNTAANIVLQALGGP -AAFTAFMRDIGDRSTRLDRMEPDLNVVPAGTDQDTTTPEAAANSLKELITGELLAAPSKA -QLIAWLSANTTAKHMLRPHLPEGWTIGDRSGASRDRKRSVIAVIYPPDQAPVFVAVYLHL -EKAGIAERDAIIAELGKSIFD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SET1_9BACT --dDLAAKIVQLEQEKQARIGVAVTDQAGRTVL-GHRENERFALCSTFKLPLVAQVLWRID -QGREKSSRPLAYNVDALQEYAPVARRYAPSGMTVQEASLAALQWSDNTAANLLLDTLGGP -AGFTRFVRQNGDSTTRLDRPEPDLNSNQPDDPRDTTTPLAMSRLTSRLLWGNTLRPATRQ -QLQRWLIGNSTGDTTIRAGLPAGWLAGEKTGSCDLGGRNDAGFVRSPAGKNHALAIYTLA -PQLEPKERDALIAETARLVTA-- ->[subseq from] class A beta-lactamase n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=UPI0011A39115 ---ALENKLNELEQREDARIGLALIDTQTGTEF-SFRGTERFALNSTFKAFACGALLSQAE -AGGPNLSESRSIREDDLVSWSPVTKNRVGTDITLRESCEATMVYSDNTAANIVLQALGGP -AAFTAFMRDIGDRSTRLDRMEPDLNVVPAGTDQDTTTPEAAANSLKELITGELLAAPSKA -QLIAWLSANTTAKHMLRPHLPEGWTIGDRSGASRDRKRSVIAVIYPPDQAPVFVAVYLHL -EKAGIAERDAIIAELGKSIFD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5R0S7_9BACT -------------------------------------------MCSTFKFLAAAAVLKRVD -EKQEKLERFVPYDAKEILEYAPVTKEHLKDGMTLGALCEAAIEQSDNTAGNLLLDAIGGP -AGLTNFARDLGDRITRLDRKEPDLNSAIPGDERDTTTPGSMLGEMTRLLTGDVLSQLSRR -QLEDWLQGNKTGAAMIRAGIPANWIISDKTGRGANGATNDIAIMHPPGRAPILLAIYSVG -STATADDRAAAIAEAAKIVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050CA72B -----EQPYSQLEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLMLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. Y81 TaxID=2058897 RepID=UPI000CE3616C ----LMRRVERLEREFSARVGLFVADGLTGAEF-GHRADERFAMCSTFKVYAAAAVLERAR -EGLTDLNRGIRIDPAGVVVNSPECADFAGSTLPLKWFCKVALTHSDNTAGNQLLEELGGP -AAIGAYARSLGDTETRLDRWEPELNNAERGDPRDTSTPRALAQGYRKLLLGDALSPETQT -RLTGWMLANVTSGTRIRAGLPGGWTSADKTGAGLFGTVNDVGIIRNPAGEPLVLAILTDS -ATADTPGSNELVAAVTRAVT--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0003606E05 -----DEAFARLEREYGAHLGLYAVDTGSGREV-TWNDTRRFSYNSTIKASLAAAVLHKNG ---IDGMDRVLHYDRSDLVANSPVSEKHVDSGMSLRALCDAAVRYSDNTAANVLFEDIGGP -GRLGEFLKSLHDKTTRTDRHETGLSEWSPGEKHDTSTPRQMASNLRGLVLGDTLPTAERR -QLTTWLRTNTTGATTIRAGLPKGWIVGDKTGTGYYAARDDIAVIWPPGRKPLVMAILTYR -DGKNAEANDKLLADAARAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Brachybacterium sp. CFH 10395 TaxID=2585206 RepID=UPI00126619B0 --rDLRRALADLETAHDARIGVSARVVGDSPAL-THRGHERFALASTGKVLTSALVLREAT ---EERLQQIIRFTAADLEEYSPVTSEHVDEGMRLLELIDAALTRSDNTAQNLLFTELGGP -RAVQRRLRRLGDGVTRTDRTEPELNTAIPGDARDTTTPAQMATDLERATLGHALGRDRSA -QLLAMMRANTTGDAAIRAGVPSTWTVADKTGAGGYGTSNDIAVITRPHAAPLVLAVYTTG -RTEDAELPTDLIAQVTRHVVD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudonocardiaceae bacterium YIM PH 21723 TaxID=2340915 RepID=A0A419HFK3_9PSEU --------LVELERGFGGRIGVSALDTGNGRTV-RYRSRERFMSCSTHKVLTVAAVLQARH -QQPGLLDRVIHYTQADCDAYAEITKRHVNEGMTVRELCDAAIRYSDNCADNLLFQLVDGP -AGVTRYVRGLGDRMTRLDRIEPELNKD-TGDDRDTTTPLQIGETLRWLTLGDKLDPVGRG -MLNDWMIRNTTGGDTIRKGLPVDWTVGDKTGTGTDNERNDIAVLWPPNRAPWIITVFTDP -DDPKSTKGNETIEKATAIVVKH- ->[subseq from] Class A beta-lactamase n=1 Tax=Cellvibrio sp. KY-GH-1 TaxID=2303332 RepID=A0A5J6PEL0_9GAMM ----VEKEIKFIEKNLSAHIGVAVLNTKTGGHW-HYKGNERVPLASTFKTIACAKLLHDAE -SDKALLGRTVLVKSDELVAYSPITEKYVGQEITLKDACAATMQTSDNTAANIIINAVAGT -QGITDFIRSIGDDVTRLDRFEPELNEALLNDIRDTTTPNAITKTINTLLFGPVLSKPSQL -QLKEWMINNQVTGNLLRSVLPEDWKIADRSGAGGFGTRSITAVVWGEAQPPLIISIYIAQ -TEASFSERNEALVRIGQSIFNSy ->[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4B TaxID=2714925 RepID=UPI00140E1284 ---HFQQRLQALEARSGGRLGLSVQVLGGQTSL-GYREDEAFPMCSTFKLLLAARILHLSQ -LGEFPLEQALLYEKKDLVAYSPATEKHADAEMTIRALCEAAVVLSDNTAANLLLGLQGGP -AGLTRWLRTVGDMRTRLDRTETDLNTAIAGDPRDTTTPRAMGRAALALLTDKLLSPESQK -QLRDWLLASRTGDKRLRAGMPSDWKVGGKTGSGDNGTANEVSIVWSAQGAPMMVSAYLTG -AVVESDGRDAILAEVGKIAADWy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aichiense TaxID=1799 RepID=A0A378UMY4_9MYCO -------DLTPIEDRYSARVGMYALDLDTGGSL-EHRADTPFSMCSTFKTYAVARVLQLAE -LGRRDLAMTQQIAASDIVENSPVTSAHVGRSMRLDELCSAALINSDNAAGNLLLRCIGGP -PEITTFARSVGDDRSRLDRWETELNAAVPGDPRDTTTPRALSAGYREVLTGKVLNDGHRE -QMLGWMSRNATSEKRFRAGLPTGWTSADKTGAGSFGSTNDAGLLSGPNGQRIIMAVLTRS -RDPDAPPLNNAIAETVRLTLAAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=M4QHK6_9BACT -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAISNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEGIKLQDHFCARPFRLAGFIADKSGAGERGSRGIIAALGPDGKPSRIV------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. SMB37 TaxID=2512213 RepID=UPI00104E1377 ---ALDERLAEIENRHAVRLGALAHSPGSGRTY-THRGDERFAMCSTFKVYAAAGILQLES -QGRLRLDDTVAVEPGDIVVNSPVTSENQGRLMTYEQLCEAALTRSDNTAGNLLLRRLGGP -DAVTTFARSVGDHATRLDRWEPELNDAARGDERDTTTAVGLARGYRDLLLGSALDPAHQR -ILTGWMRASTTSDTRMRAGLPSGWVAADKSGGGYFATLNAAGVVWSPEGEPLVLVILSDT -TTVDAPFENAPIVDTTAAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C826A26 ------QSIEQIESRVSARIGIAVYDSGTKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI0010BDF6E5 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio tasmaniensis TaxID=212663 RepID=UPI00031AD7EA -----SQSIEQIEYRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYEFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVETLNELVYGNMLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWNIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=UPI0012F8C5F3 --kAIDSDLKKLEKEYEATLGVYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQTMMINQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEATPGDRRDTSTPKAIALDLKKLTLDKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDVLVGDKSGAASYGTRNDISVLYPQNRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVSDYf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CECT 8783 TaxID=2358193 RepID=UPI000F0B72FD ----VHDRIEALQRRHNAKIGVYTINLDSGRTV-SHLDGESFAMCSTFKGYAAARVLQMVQ -NGELTLDRQVFVDPEQTSLNSPRTAANSGGQMTLAELCAAAVQVSDNAAGNLLLQTIGGP -SAITDFARSIGDDRTRLDRWEIELNTAIPGDPRDTSSPRALGGGYRNLLTGDVLAAPQRQ -QLEDWLRANET--SSMRAGLPEGWTTADKTGNGDYGSTNDVGMAYGPRGQRLLLAIMTRS -QANDAANNRPLIGELTTL----- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. SMB37 TaxID=2512213 RepID=A0A4R2DEL9_9NOCA ---ALDERLAEIENRHAVRLGALAHSPGSGRTY-THRGDERFAMCSTFKVYAAAGILQLES -QGRLRLDDTVAVEPGDIVVNSPVTSENQGRLMTYEQLCEAALTRSDNTAGNLLLRRLGGP -DAVTTFARSVGDHATRLDRWEPELNDAARGDERDTTTAVGLARGYRDLLLGSALDPAHQR -ILTGWMRASTTSDTRMRAGLPSGWVAADKSGGGYFATLNAAGVVWSPEGEPLVLVILSDT -TTVDAPFENAPIVDTTAAL---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0R2_9BACT -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTYKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=UPI0005D8CF7F ------VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD -AGKEDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSIANSASKILLGNVLSPQSRA -QLEKWMIACKPGLNRLRAALPADWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA -PALGMPAREAVLREVGAVFV--- ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia TaxID=1822464 RepID=A0A2N8Q8M0_9BURK ------VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD -AGKEDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSIANSASKILLGNVLSPQSRA -QLEKWMIACKPGLNRLRAALPADWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA -PALGMPAREAVLREVGAVFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. K24 TaxID=1472716 RepID=UPI0004AA9A82 ------VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD -AGKEDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSIANSASKILLGNVLSPQSRA -QLEKWMLACKPGLNRLRAALPADWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA -PALGMPAREAVLREVGAVFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus biphenylivorans TaxID=1500843 RepID=A0A2Z4VQ14_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -AGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPDLNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C467C -----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTSIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=I3VLI2_9BACT ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVLERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P9-64 TaxID=2024612 RepID=A0A5A7WQ70_9MYCO ----VEQLIAGLEQAHNAVIGVYAVNLISGVTI-AHRARDPFAMCSTFKTYAVARVLEMVG -RGQLTLDQPVLVDPAAVVANSPRTGPRAGTEMTLSELCQAALQVSDNTAGNLLLHTIGGP -PAITAFARSIGDQQTRLDRWETDLNSAIPGDLRDTSTPEALGSGYRALLSTEAPGPSTRQ -TLLDWMRANET--SSMRAGLPPGWTTADKTGSGGYGTANDVGIAYGPDGQHVLLAMMTRS -QADDAATLRPVIGELTSL----- ->[subseq from] class A beta-lactamase n=1 Tax=Marisediminicola sp. SM7 A14 TaxID=2711233 RepID=UPI0013ED7C95 ------AEFDELEARYDATLGVFAVDTGTGVEV-EWRADDRFAYASTIKALAAAAALGRFG ---IDGMQQPVAIASSDLVSYSPVTETRVGGSMTLAEIADAAVTLSDNTAGNYLFEALGGP -GELDRALAVLGDDTTTVSRIEPQLNEAAPGDERDTSTPRAMAGSLREYVLGDALPEAERA -QLTEWLVASQTGGSLVGADLPGDWTIGDKSGAGGFGTRNDIAVVWPSTGEAIVIAVMSTR -GVEGAEYDDRLVAEAAAIAV--- ->[subseq from] Class A beta-lactamase GES-32 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1B3B597_PSEAI ----FRTDLEKLEREKAAEIGVAIVDPQGQIVA-GHRIEQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGRDMIVKWSPAAERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTPTSTH -TIERWLIGNQTGDATLRAGFPKDWVIGEKTGTCANGGRNDIGFFKAQDRD-YAVAVYTTA -PKLSAEQRDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=2 Tax=Shewanella sp. SNU WT4 TaxID=2590015 RepID=A0A4Y6I9Z8_9GAMM ---NLQTQIEYWQTKLQVKIGVAVLNTANGQYW-GFQDEQRFPMASTMKMLACAKLLYDAD -NNRLQLSDKVTIEAADIITYSPMTEPLIGQAISVNDACQMTLTSSDNTAANIVLDAIGGP -VALTQFLRAQGDAITRLDRCEPELNQGMPEDVRDTTSPKAVVHTWQQLLTAKVLSESAKA -QLTTWLQHNQVANDLLRKTLPQGWLIADRSGAGGYGARGIVAMVWQPEQAPVFISIYLHQ -TTASMEQRNQAIAAIGDAIF--- ->[subseq from] Beta-lactamase n=3 Tax=environmental samples TaxID=48479 RepID=X2KVC5_9BACT -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTVAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAGTPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans SB3094 TaxID=1435356 RepID=V9XHD3_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI0007CD6926 ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. RS1C4 TaxID=2022522 RepID=UPI000B9C684E ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILVVVLSRT -ANPDAAAMNELVADAVREVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter castelli TaxID=271431 RepID=UPI0009D6F561 ---SVKASFAELEEQYQGRVGVYAVDTETGHEV-QYRADERFAYASTHKVFSVAAVLAQSE ---PADLDEVVHYSSEDLVEYSPVTEKHVDSGMTVRSIMRAAIINSDNTAGNLLFDMLGGP -EGLQAYLAKLGDRTTSVDRIEPELNKWKPGQRRDTTTPRQAVTNLAALTHGNALEPWAQK -VLLEAMRDAENSDGLIRAAVPASTTVGNKSGAGGYGTRNDIAVIEREGQAPVFVAVYTNL -EDSDGVFDDAFVADAARAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C823892 -----SQSIEQIEYRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYEFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVDTLNELVYGNMLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TELTIQERDTVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0005171845 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRIFFGEKDLVAPFKATKPHIADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTTYLRSIGDQTTRVDKTELALNIVKPGEKHDTTSPRAMVGTLQRVVLGSALSPTSRA -LMTDWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIIVAAYLGK -ARGSVTDQEAVLAEVARIIT--- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella TaxID=570 RepID=UPI0003BEDA63 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRIFFGEKDLVAPFKATKPHIADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTTYLRSIGDQTTRVDKTELALNIVKPGEKHDTTSPRAMVGTLQRVVLGSALSPTSRA -LMTDWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIIVAAYLGK -ARGSVTDQEAVLAEVARIIT--- ->[subseq from] Class A beta-lactamase GES-35 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2U8YKA8_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPELGDNTPGDLRDTTTPIAMARTVAKILYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A495NF03_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI00083782D8 ---------DRIRGETGARLGVAVYDSGTGRRF-SDGAEARFAMCSTFKVPLVAAVLARVD -RGELDLAREIRFGEADVLDYAPVVKANLAKGLSIDALCEAAVVMSDNSAANLLFGQISGP -RGLTKFIRDAGDQLTRSDRDEPSLNNVRNGEVRDTTTPEAMLWLMNRLLLGDVLTPASRA -KLIGWMEASPTGKDRLRAGLPKDWRVGDKTGTSGEGYFNTIAIATPPGRKPILITCYLDA -PGLNSAKANAAHAKVGELVG--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudescherichia vulneris NBRC 102420 TaxID=1115515 RepID=A0A090VWE0_PSEVU ----LQAFLEQEETRLPGKIGMSIVNADGQPIF-GYRQNERFPLTSTFKVLACAALLDRLH -KTAGLLDQTVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILTYLGGP -AAVTRFMRESGDTVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPLLTKPHQA -MLESWMREDKVADNLLRAALPKGWFIADKTGAGGYGSRAIIAAVYPTGEKPVYMAIYITQ -TDAEMKVSDGVIQKIGER----- ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=UPI0007826EF0 ---------SSYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD -QGKESLETVVPYTASDLGDYAPVAKANVAAGLSVRAMCQAAVEWSDNVCANLLLARVGGP -AALTRFWRSLGDRQTRLDDWEPVLNRTPQGGLRNTTTPEAMAWILEHLVFGHALSGASCS -LLTGWMKNCQTGKGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG -GQPNEKQFFEVFSEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D11E1E ---------QRVETELGMRVGFAVLDMGSGEVR-RYRAIERFAMASTFKALACAAALSA-- --GPSVLDKQTRISKADLRPHSPVTEKRVGTSLSTRALCEITLRTSDNAAANAVLAAIGGP -PAVTTFLRGIGDDTTRLDRYEPELNEATPGDPRDTTTPQAMAETVRRLLLDHALEPKARD -QLEAWMAANAVAGALLRAELPKGWAIADRSGAGGHGTRGVIALLRPPEDAPLVVAIYMDG -RKHPLKVRDAAIAEIGAAIFAEy ->[subseq from] Beta-lactamase n=1 Tax=Nocardia sp. CS682 TaxID=1047172 RepID=A0A4P7GYD3_9NOCA ---RATAQVRDLESAHHARVGAFAVDTKTGVFL-GYRENERFPIGSTFKTLAVAALLREHP -LADGYFDTVINFTADDLVKYSPVTETRVGTGMTVRELAAAAIEKSDNTATNELLKLLGGP -TAITKFVRTLGDTATSLDDWEPLSNSGDTNPEHNSTTPAALAADYRALVSGDALPAPERE -QLIEWLLRSTTGLNRIRAGLPQDWKTGDKTGGGDYGLTNDAAVTWPPNSAPIVITVLSIN -TEENAPADDPLVAQSAKAITE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. SRS-46 TaxID=2094191 RepID=A0A4R4CDL8_9BURK ---AAHSQLDALEKASNGRLGIVALDTASGARI-AHRSRERFPMCATYAPVAVAAMLARSA -LDPSLLPRRTLYRRYELVPGSPVTESRADTGMTIGQLCEAVLQSDDKSAANLLMRVLGGP -RVVTAFAHDSGDTSFRLDRWEPALNTAAPGDERDTSTPLAMAESLRRLLLGDVLREPERT -QLTKWMLGNTSGFAGIRAGVPSDWRVASRGGAGGYGTTTDVAVLWPTSHAPLAMAVSFTQ -PDADAAPHADVVAQAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Listeria newyorkensis TaxID=1497681 RepID=UPI00051DD231 --eEAKAELKKLEEKYGATLGIYAVNTADKKKI-SYNDQERFAYVSTYKAIAGGLLLKNLT ---TEQLNKRIYFSKEDLVDYSPVTEKHVDSGMTVKEIINAAMTYSDNTAGNILFQQLDDP -KGYQKELAKIGDKTTQADRLEPELNEAVPGDKRDTTTPEAMANVLSFLTTKGNMASDRLD -YFKQTLIDNTTGDKLIRAGVPAGYTVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK -SGKDDEYNDQLIADAAKVLSNYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia catarinensis TaxID=1108140 RepID=A0A1J9NQP4_9BURK ---AAQAELAALETASNGRLGVAALDTSNGVRI-AHHAASAFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIAQLCEAMLQSGDKGAGNLLMGVLGGP -QAVTSFAHESGDTTFRLDRWEPELNKVAPGDERDTSTPVAMVDTLQRLLLGDTLQEPQRA -QLTEWMAGGARGATGIAAGVPPGWRIAGNAGTGGYGTTTDIAVLWPPSRAPLVTAVSFTQ -PQADAAARADVVALAARIAA--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacterium TaxID=1763 RepID=A0A1S1NGH5_9MYCO --------VEDLERRRHATIGVFAVNLSSGRSV-AHRAGEPFAMCSTFKVYAVARILQLAH -HGELRLDHAVRVDPTAIVANSPRTQPRAGGDMTIDELCRAALQRSDNTAANLLLTIIGGP -PAVTAFARSIGDQRSRLDRWETDLNAALPGDPRDTSTPEALGGGYRALLVGDALAPEHRQ -LLNNWMRANET--SSMRAGLPPGWTTADKTGSGDYGSTNDIGIAFGPEGQRVLLAMMMRS -QTDDPN----------------- ->[subseq from] Beta-lactamase n=1 Tax=Actinoplanes sp. N902-109 TaxID=649831 RepID=R4LF89_9ACTN ---------------------MYALDVKSGHAV-AYRADERFAYASTYKALAAGALLAHTS ---DADLDDMVTYQRADLVAHSPVTGKKLADGISIGDAAEAAVRVSDNTAANLVLRELGGP -AGWEKDLRGVGDTVTEAARTEPELNAATPGDKRDTSTPRALAADLRAYVLDDALDAGDRS -TLTRWMTGNATGNTLIRAGVPKGWTVADKSGGGQYGTRNDIAVVWPEPDRPLVLAVLSSR -AGADADYDDALIARAASVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Selenomonas sp. mPRGC8 TaxID=2606905 RepID=A0A5D6WED5_9FIRM -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKQ -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Pusillimonas sp. (strain T7-7) TaxID=1007105 RepID=F4GRQ5_PUSST -------LLAALERNHGGRLGVAILDTATGMRS-AYRGDERFLICSTFKLLLVAAVLKRVD -NNKERLGRRISFDKSEILAWAPVTSLNVGSPMSIQELCEATMIMSDNTAANLLLKTLGGP -AAITTYARGLGDTKTRLDHIEP-LNGNQQG-DEDTTTPWSMLQNMQKILLGNALSEESKT -RLVNWFSMNQTGSQALKAGLPPDWLIGDKTGAASN-ANNDIALITPPGRQPILVTAYYIN -DTKNSRARKEVLAKVGS------ ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI001303DF66 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAMPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDSTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRPDAAPIVITVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio sifiae TaxID=566293 RepID=A0A2S7XJ09_9GAMM ---SLTENIEAIELSSSGTIGISVLDTATNTTW-NYKGDQRFPMMSTFKTLLCAQMLYNSS -DGILDKQAQTRITQEALIPWSPITEKQIGETITTEKACEATMLMSDNTAANIVLAEIGTP -SSLTLFLRFIGDNTTRLDRIEPALNEAKSGDIRDTTTPNAMTNTLNELLFGQTLNAKDKR -TLKAWMVNNKVSDPLLRSILPQQWFIADRSGAGGFGSRGITAIVWSEQRSPIIIAIYLKQ -TDLNIAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. ADI91-18 TaxID=1522755 RepID=UPI000F553EE8 ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCTAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=UPI00076A6F55 ---SLTENIEAIELSSSGTIGISVLDTATNTTW-NYKGDQRFPMMSTFKTLLCAQMLYNSS -DGILDKQAQTRITQEALIPWSPITEKQIGETITTEKACEATMLMSDNTAANIVLAEIGTP -SSLTLFLRFIGDNTTRLDRIEPALNEAKSGDIRDTTTPNAMTNTLNELLFGQTLNAKDKR -TLKAWMVNNKVSDPLLRSILPQQWFIADRSGAGGFGSRGITAIVWSEQRSPIIIAIYLKQ -TDLNIAERNQVIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas iranensis TaxID=76862 RepID=UPI0013D02FCD ---DVAAALADVEARHGVRLGVHALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- --GVAGVDERVPVEADDLVTYSPVAEQRVGVGMTWRELVDAALRFSDNTAGNLLLAGAGGP -AALTAWLRGLGDDVTRSDRTEPELNAYAPGDDRDTSTPRALAGTYRALVVGDVLGGPERD -LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTPAGAPVVLAVLSDR -ADPAAERADAPVAQAARVVLD-- ->[subseq from] Beta-lactamase n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A097ZLX5_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI0009A58B97 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAALLRAHALGDPLDADERA -LFTGWLKATHTGATLVRAELPADWTVGDKSGLGEYASRGDVAVIWRADAAPIVIAVHSAK -DQQDADADDALISGAAKAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-1411-2a TaxID=2023151 RepID=UPI000B9B57A2 ------QVYLDFEARDNARLGVSAVDLASDSTE-NHRGDERFAFCSTFKVYAVGAVLAAVD -AGTLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLASAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTTDSRE -QLLAWMADTQTSDARFGAGIPDGWTSADKTGTGSYGVSNDAGLLLGPGGQRILVVVLSAT -TSEDSPAMNALVADATRAAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus pyridinivorans AK37 TaxID=1114960 RepID=H0JPL8_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDSEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. ADI95-16 TaxID=1522758 RepID=A0A3G4VPX0_9ACTN ------GALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVAGGMTVEALCAAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTNDTTSPRAIGTSYGHLLLGEALNPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMAVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5C0PBD5_PSEAI --qQVEQDAKVIEASLSAHIGISVLDTQTGEYW-DYNGNQRFPLTSTFKTIACAKLLYDAE -QGEINPKSTIEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIESELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLEYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Mg1 TaxID=465541 RepID=A0A0G3UI28_9ACTN ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB03578 TaxID=1718987 RepID=A0A1Q4Z3U9_9ACTN ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 1274761.0 TaxID=1834077 RepID=A0A1A3SP98_9MYCO ------DRIETLQRRHNARIGVYAVDLASGRTM-SHLDGETFAMCSTFKGYAAARVLQMVA -DGELSLDRQVFVDPVQAALNSPRTAPNAGGQMSLADLCAAAVQVSDNAAGNLLLQTIGGP -TAITDFARSIGDNRSRLDRWETELNSATPGDPRDTSTPNALGGGYRRLLTGDVLAPPQRQ -QFEDWMSANET--SSMRAGLPSGWTTADKTGNGDYGSTNDVGMAFGPGGEKILVAIMTRS -QSNDAPNNRPMIGEVTAALV--- ->[subseq from] EsbL n=1 Tax=Escherichia coli TaxID=562 RepID=H6U587_ECOLX ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas turrisvirgatae TaxID=1888892 RepID=A0A1E3LUG6_9SPHN --------LARLRDETGGRIGLAVFDTGTGRRY-FDGAEARFAMCSTFKLPLAAAVLEAAD -RGRVDLKRDIRFGEADLLDHAPVVKANLAKGLPIATLLEAAVVMSDNSAANLVFGQIGGP -RGLTKFFRDAGDSVSRSDRDEPELNNVRDGDLRDTTTPQAMLWLMNRILLGDVLSPASRA -KLIGWMEASPTGKDRLRAGLPKAWRVGDKTGTSGDGYFNDIAIATPPGRKPILIACYLDA -PGIDGAKANAAHAQMGALI---- ->[subseq from] Bla(GES-14) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C5HUY1_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Extended-spectrum beta-lactamase GES-11 n=4 Tax=Pseudomonadales TaxID=72274 RepID=I3VFR3_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] GES family class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0009A9A4C7 ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderiales bacterium PBB2 TaxID=2015564 RepID=A0A257FLG3_9BURK -----DAACRALEARLGGQIGVFALDTGSQARL-AYRADQRFAMCSTFKLLLAAAVLARID -AGQLRPDQRLRYGPRDLVPHAPVTGALLQGGLTVAALCEAILVHSDNPAANLLLPLVGGP -PGLTRFAREQGDVITRLDRIEPALNSNEPGDPRDSSTPEAFVGLLDRL-LGSVLSDELRQ -QLLVWMNASETGLRRLRAGAPQDWPAADKTGTGARGAVNDVAVFFPPQRAPILMAVFMSG -SSQPLAALEAAHAELATRA---- ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter TaxID=434 RepID=A0A252EJX7_9PROT ------TAISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD -GGLDALERQISYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSASSRT -ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=BLAC_RHOCA --eALSETVARIEEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAILARWD -AGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGHLGGP -EAVTQFFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSPEARG -KLAEWMRHGGVTGALLRAEAEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATMFISD -TDAEFEVRNEALKDLGRAVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F5AFE05 ---AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLMTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2L1J0Z6_ECOLX -------------------LGVALISTADNSQI-LYRADERFAMCSTRKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] class A beta-lactamase n=2 Tax=Pseudonocardia TaxID=1847 RepID=UPI00091B3059 -------ALADVEREYARTIGVHVLDTGTGAAA-GHRDGDRFLMCSVVKALMAGFVLHRSL -SEPGLLDRPVRYGRADLLEYAPVTTRNLAAGMTVAQLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALAATLRTLVLGDALPPAQRD -RLTGWLRANTTGDRQIRAAVPAGWTVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP -ADADTARGEAAVAAAARAAI--- ->[subseq from] Beta-lactamase n=1 Tax=Stackebrandtia endophytica TaxID=1496996 RepID=A0A543AW05_9ACTN ---DISAEIADLEAQYGAVVGVYALDTATGQEI-AYRADDRFAYASTIKALAAAAVLHRPD ----TYLDELLTYTADDLVPHSPVTERHVDTGMTLGEVVDAAIRESDNTAGNLLFQRLGGP -EGLRAALRDIGDDTTTPTRWEPDLNGFEPGDDRDTSTAAALATSLLRYA-TEVLDEEDRT -TLITAMLGVRTGDGTIRAGVSAGWQVADKTGTGDHGTRNDIALLWSDEGDPVVLAVLTRS -VDPDGEPSDSLVAESTAIAM--- ->[subseq from] GES-22 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=K0GF29_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPELGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-621-2 TaxID=2022500 RepID=A0A259XSL9_9NOCA ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ANPDAAAMNELVADAVREIV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A3N7VN92_9BURK ---AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007591722 ---AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0F7LGM5_ECOLX ---------------FGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADK------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI91-18 TaxID=1522755 RepID=A0A3N6CSM7_9ACTN ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCTAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLLGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Kushneria sp. YCWA18 TaxID=657387 RepID=A0A1S1NRK7_9GAMM ----VVERLKALERQHGSRLGVAICDIASGRCV-RHRANERFLLTSTGKVMAAALVLARVD -RGREQLTRRIRFEQQDLLEWSPITRQYAGPQMTLEALCRAAITHSDNTAGNLLLTSFGGP -TALTAYTRSLDDRVTRFDRIEPALNEDSEDDQRDTTTPWAMLGNLRKLLFADALSSASRH -HLSAWLVESQTGSDRLRAGMPDTWLIGDKTGTNASGAVSDIGVAWPGHRGAMLVTAYCHL -PAASKEERDGVIAEIGRLTA--- ->[subseq from] Carbapenemase n=1 Tax=Escherichia coli TaxID=562 RepID=H6U588_ECOLX ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] GES family class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00106B09BB ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 852002-51564_SCH6189132-a TaxID=1834103 RepID=UPI0007EC1320 ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAELPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075DA37B ---AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Class A beta-lactamase n=23 Tax=Bacteria TaxID=2 RepID=Q6RSM8_ECOLX ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] BlaGES-5-like extended-spectrum beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A2THF2_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 234 TaxID=1918495 RepID=UPI001390A194 ----AATEFADLEDRYQAIIGVYGVDVVSSATV-EHRPDERFAMCSTFKAYAAARILQLSQ -DGKVDLDASVRISAGDIVVYSPVVSRAVGSSLPLRDICAAALQQSDNAAGNIMLRTIGGP -SAITDFARSIGDSQTRLDRWEPDLNTALPGDLRDTTTPRALCGGYRAILVGDALRPSDRF -QLQQWMLANTTSTKRFRAALPSGWTSADKTGSGDYGSSNDAGLLSGPTGERVMLTVLIRS -RTKDSGLFDEAVAATARLALD-- ->[subseq from] Beta-lactamase n=1 Tax=Brucellaceae bacterium VT-16-1752 TaxID=2487907 RepID=A0A3P1UFL7_9RHIZ ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVIPFKATKPHLADGMTIEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKPGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGIATNDIGVIFPPDRPPIVIAAYLGK -ARGSIVEQEAVLADVARIVTT-- ->[subseq from] Beta-lactamase L2 n=2 Tax=Sphingomonas sp. T1 TaxID=2653172 RepID=A0A653YUQ6_9SPHN ---------TDYEAASGGHVGIYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA -LLMLWLRQCRTGDARLRAGLPRAWVIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG -GTPTEAQFKTLFSEVARGVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_38_11 TaxID=1798278 RepID=A0A1G0HC23_9GAMM ---TVSQRLNQLEIKNHVEIGLSAIETYNNTQI-NYHANKRFPMDSTSKLMTVSAILKKSE -TDPALLNRKIFFTMNDVKKYAPITVKHIKSGMTVSALCAAALEDSDNVAANQLMKILGGP -SKVTQFARSIGDEKFLLVRWEPALNSAIPNDKRDTTTPSTMTESIQKLVLGNALGKSQRQ -QLQVWLKHCKTGNHRIRAGVPDHFIVGDKTGTGGYGSIGDIGVVWRPQASPIVLAIYARQ -NEKKAQTPDKVIAKATKIVMN-- ->[subseq from] GES-9 n=3 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q49HG5_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGSRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Aeromonas media TaxID=651 RepID=UPI0009DDF7AC ------------FEKQGWRVGVTVLDTKSGEHE-SINGDQRFHFNSTIKALACANVLEKVD -KGQLTLNDSFILKESDIVTHSPVAEKLVGKRFTLGDACEATLTYSDNTGANYAISSVGGP -AGLTSFMRSMGDNVLRSDRYEPELTKNIEYDIRDTTTTDAMALSLNKLLLQDVLSTESRA -QLKQWMMGNRVADDLLRASLPKGWSIADRSGASDYGVRGIISMVWSETQHPIVITMYVRK -EGSSIHERDKVIADIGSVIFGAy ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-16 TaxID=2013662 RepID=A0A2N3D0A7_9PROT --------LDRIREETGGRLGVAVFDSDSGRRF-FDGAEARFAMCSTFKMPLAAAVLARAD -RGEIDLNREIRFGEADLLEYAPVVRANLAKGLPIDTLLEAAVTVSDNAAANLLFGQVSGP -RGLTAFIRDAGDVVTRSDRYEPELNVVRGGEVRDTTTPMAMLWLMNAVLLGDVLSPASRA -KLIGWMEAASTGKERLRAGLPKGWRVGDKTGTSGEGYFNDIAIATPPGRKPILIACYLDA -PGLDGAKGNAVHRQVGELVG--- ->[subseq from] Beta-lactamase GES-4 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q764B7_KLEPN ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis flava TaxID=1507287 RepID=A0A1T4ZU88_9SPHN -----AGRLAALERQAGGRLGALFLDAASGRVT-GHRADERFALCSTVKWPLAAVILKAVD -AGTVSLEQPIRFGKSDLLSNSPRTRDNLAKGMSVAELLEATITVSDNAAANLLLPLVGGP -EAVTRQFRAWGDPVTRLDRAEPMLNLVGEGEVRDTTTPAAMAALLRTILLGDVLSHASRK -RLTDWGTATTTGPKRLRAGLPASWRLGHKTGTAMMNKYNDIAIAFPPEGAPLLIAVYYEG -PVTIRSEDEAVLAAAGKLAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aubagnense TaxID=319707 RepID=A0A5R8SJ61_9MYCO -------SFEDLEDRYQALIGVYAVDLESSATV-EHRADERFAICSTFKAYAAARILQMAK -TGHANLDAMVPITAADIVVNSPVLSPAVGARMALRDICAAALTQSDNAAGNIMLRTIGGP -SAVTDFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALPGASQY -QLQRWMSETTTSTRRFRAGLPAEWTSADKTGSGDYGSTNDAGMLIGPKHERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured soil bacterium TaxID=164851 RepID=M4QA56_9BACT ----------------DARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEGIKLQDHFCASALPAGWFIADKSGAGE-------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519J0Z1_9CAUL -------DLSALEARHGGRLGVSALDIAFNRSV-SWRGQERFAYCSTFKLFLAAAALERVE -RGEERLDRSIRITRADMISHAPVTGPAVGRGLTVQALCQAMVEVSDNPAANIMIREMGGL -NAWRDWLRTLGDTSTTVNRWEPDLNSAMADDPRDTCLPDQTVGNLREVLLDERLTAGHRR -LLEDWMLASPTGPNRIKAAAPTGWTVAHKTGTGANGATNDIGLLRPPSGQPVLVAAYFTE -APATTAQREAVLAQGV------- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio tasmaniensis TaxID=212663 RepID=A0A1A6IYT1_9VIBR ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLSGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNMLSQESKL -KLKSWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae TaxID=36814 RepID=A0A1X0J5I5_MYCRH ----VEQRIADLEKRHNAFVGLYAQNLDSKVDL-AHRDGDPFAMCSTFKSYLSARVLQKAQ -AGELRLTDTMLVDPAELKPNSPRTEPNAGQPMAIADLCAAALQVSDNTAANMLLRTIGGP -PAITAFARSIGDDRTRLDRWETELNSAVPGDPRDTSTPRALGGGVARVLTGDVLDGPHRT -QLQDWMRANTT--SSMRGGLPAGWTTADKTGSGDFASTNDVGIAFGPNGERVLLAIMTRT -RSAQAEPLRQLIAEVATLA---- ->[subseq from] Beta-lactamase n=23 Tax=Bacteria TaxID=2 RepID=A0A127SUT1_9BACT -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia ninae NBRC 108245 TaxID=1210091 RepID=A0A511M8T2_9NOCA ---RATAQVRDLESAHHARVGAFAVDTKTGVFL-GYRENERFPIGSTFKTLAVAALLREHP -LADGYFDTVIHFTADDLVKYSPVTETRVGTGMTVRELAAAAIEKSDNTATNELLKLLGGP -TSITKFVRTLGDTTTSLDDWEPLSNSGDTNPEHNSTTPAALAADYRALVSGDALPTPERE -QLIEWLLRSTTGLNRIRAGLPQDWKTGDKTGGGDYGLTNDAAVTWPPNSSPIVITVLSIN -TEEHAPADDPLVAQSAKAITE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium DCM004Carb02 TaxID=1471931 RepID=X2KZB4_9BACT -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Class A beta-lactamase GES-25 n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A0M4NJD6_CITFR ----FKTDLERLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Caballeronia humi TaxID=326474 RepID=UPI00117D7380 -------PLADIEHRHGGRLGVYAIDTGTGHTL-EHRADERFLMCSTFKGMLAAQVLARVD -AGKERLDRLVQYTAQDLIFTSPVTKANVARGLPVHTLCQAIIEQSDNTAAILLMRGAGGP -AALTQFMRGIGDEVTRSDRYEPDSNRY--SGVLDTTTPRAIATAARAVLLGDVLRPASRA -QLERWMIDCKPGLNRLRAVLPAGWLAADRPGTSVEEQTNDYALVRPPGRAPLLVAAYYDA -PGMSMDEREAVLREAGKVFV--- ->[subseq from] Class A beta-lactamase GES-28 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M5JBM2_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRNTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L065_9BACT -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Carbapenem-hydrolyzing extended-spectrum beta lactamase GES-16 n=1 Tax=Serratia marcescens TaxID=615 RepID=D9IR25_SERMA ----FKTDLEKLEREKAAEIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Comamonas sp. 26 TaxID=2035201 RepID=A0A2G6ZPX0_9BURK ----LSDELAALEVQAQGRLGLYALDTSSGAAA-GWRSDERFAMCSTFKTLLVAHVLSLAQ -SGQIKLWHKRYYATTEVVAWSPVSAKWAGANMTLLDLCEAAVVVSDNTAANVLLESTGGP -AALTQWLRSLGDSITRLDRNEPTLNTALTGDERDTTTPEAMLLSLQKILLADVLDGSSRA -LLHQWLLDSRTGDKRVRLGLPAQWTIGGKTGSGDNGTSCDTLIAWPTQQAPVLVTAYLTG -SKLDLAGREAVLAKAGEAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. NEAU-YG30 TaxID=2249762 RepID=UPI000DE34C54 ---QARKELRELEASFQGRIGAYALDTATGKAV-TYRPGERFPLLSTHKAILGAAMLHKAR -TEPGLMNKVLKWTAADLKPNSPTTEKHVADGLTVAQLCEATITLSDNTAANVLLKELGGP -PALTRYFRTLKDPISRLDRWETELNNWTVKEKRDTSTPAAIGRDLRALTAGNALNAKDRE -QLNAWLIANKTGDERIRAGLPKGWTIGDKTGTNTIGAGHDIAVIWPGRSAPIIMVVFTNR -EV--AAVDNKVIAQVATILA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aichiense TaxID=1799 RepID=A0A378UKR9_9MYCO -----GQRIADLEKRHNAFVGLYAQNLDSKLDL-AHRDGDPFAMCSTFKAYLSARVLQKAQ -AGELLLTDTVLVDPAELKPNSPRTEPNAGQPMAISDLCAAALQVSDNTAANMLLRAIGGP -PAITAFARSIGDDRSRLDRWETELNTALPGDPRDTSTPRALGGGLARVLTGDVLDGSHRK -QLEDWMRANTT--SSMRAGLPAGWTTADKTGSGDFASTNDVGIAFGPGGERVLLAIMTRT -QSDDAAPLRQLIAEVATLA---- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Vibrio antiquarius (strain Ex25) TaxID=150340 RepID=A7K2A8_VIBAE ------------------------WDTQTDERW-DYRGDERFPLMSTFKTLACATMLSDMD -SGKLSKNATAKIDERSIVVWSPVMDKLAGQSTRVEHACEAAMLMSDNTAANLVLNEIGGP -KAVTMFLRSIGDKATRLDRLEPRLNEATPGDNRDTTTPNAMVNTLRTLIEGETLSYESRV -QLKIWMQDNKVSDSLMRSVLPTGWSIADRSGAGGHGSRGINAIIWKENHRPVYISIYVTE -TELSLQARDQLIAQISQLILQKy ->[subseq from] Extended-spectrum beta-lactamase GES-17 n=1 Tax=Escherichia coli TaxID=562 RepID=F2YBS7_ECOLX ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q5T0F8_9SPHN --------FDRIRAETGGRLGLAVYDTGTGRRF-SDGAEARFAMCSTFKVPLVAAVLARVD -RGELNLASEIRFGEADLLDYAPVVKANLAKGMSIDALCEAAVVMSDNSAANLLFGQISGP -RGLTKFIRDAGDQLTRSDRDEPSLNRVRDGEVRDTTTPDAMLWLMNRLLLGDVLSAASRA -RLTGWMEASPTGKARLRAGLPKDWRVGDKTGTSGEGYFNTIAIATPPGRKPVLIACFLDA -PGLETAKANAAHAKV-------- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C85AB49 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp8963 TaxID=2184547 RepID=A0A3N8KZS3_9BURK ---AAQTQLDALEKASDGRLGVAALDTASGARI-AYRSREHFPMCGTYAVVAVAAMLARSA -LDESLLPRRILYRRYDVVSGSPVTESHVDTGLTIEQLCIAVLQSGDKAAGNLLMGVLGGP -QAVTGFAHTSGDTLFRLDRWEPELNTAAPGDDRDTSTPLAMTETLRRLLLGDTLGEPQRT -QLTKWMVGNPGGGARIRAAVPSDWRVADMAGTGGYGTTTDVAVLWPPSHAPLVIAVSFTQ -PRADAAPRADVVASAARLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A0U5EZX7_9PROT --------ISQHENETGGHVGFYAENTQTGATL-GWRTDERFVMCSTFKASLAACVLARVD -KGLDTLERPLSYTAADIGDYAPVAKANQAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT -ILTDWLIRCRTGEHRLRAGLPNEWKIGDKTGNNGKDAAGDIAIIWPTPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF73_9BACT ---DFAAKIVQLEQEKQARIGVAVTDQAGRTVL-GHRENERFALCSTFKLPLVAQVLWRID -QGREKSSRPLAYNVDALQEYAPVARRYAPSGMTVQEASLAALQWSDNTAANLLLDTLGGP -AGFTRFVRQNGDSTTRLDRPEPDLNSNQPDDPRDTTTPLAMSRLTSRLLWGNTLRPATRQ -QLQRWLIGNSTGDTTIRAGLPAGWLAGEKTGSCELGGRNDAGFVRSPAGKNHALAIYTLA -PQLEPKERDALIAETARLVTA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. Chr-9 TaxID=713612 RepID=UPI00068AE595 ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRANERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia acidipaludis TaxID=660537 RepID=UPI000486431A --------LAAIERRHGGRLGVFAIDTASGRTL-AWRADERFLMCSTFKGLLAALILARVD -AGQESLARLVRYTEQDLIFTSPVTKAHVGEGMTVGALCQAVVEVSDNTAAILLMRSAGGP -AALTRFARSMGDTVTRFDRYEPDSNRY--SGLLDTTTPRAITQSARSLLLGDALSLQSRR -QLENWMIACKPGLNRLRAALPADWLAGDRPGTSVERETNDYAIVRPPGRGPLLVAAYYDA -PGLAMDRREAVLREAGSVFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudescherichia vulneris TaxID=566 RepID=UPI0012AC52BF ----LQAFLKQEETRLPGKIGMSIVNADGQPIF-GYRQNERFPLTSTFKVLACGALLDRLH -KTAGSLDETVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILTYLGGP -VAVTRFMRESGDTVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPLLTKPHQA -MLESWMREDKVADNLLRAALPKGWTIADKTGAGGYGSRAIIAAVYPTGEKPFYMAIYITQ -TDAEMKVSDGVIKKIGERVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8429B9 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNNMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TKLTIPERDTVINEIGELIFDAy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A399N0R8_9MICO ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---VAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDITAANLLLEALGGP -AELDAALTVLGDDTTVVSRTEPDLNQAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDVAVIWRPDAAPIVIAVHSAK -DRQDADADDALISGAAKAAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. PS03_16 TaxID=2559611 RepID=A0A4Y9MIQ8_9MYCO -------GLEALERANSAVIGVFGTNLDTGRTV-AHRAQESFAMCSTFKAYLAGLVLSLVD -RGERSLDQRLYVDPAELQPNSPRTGPRAGGEMTLDELSQAVLQVSDNAAANILLHNVGGP -PAITGFARGIGDPRSRLDRFEIELNSAVPGDPRDTSTPEAMAGGFRALLTGDVLTPARRQ -LLGDWMRANET--SSMRAGLPTGWTTADKTGSGDYGTTNDVGIAYGPKGQRVLLAVMTRS -ATPDAENMRPLIGEVTAAVF--- ->[subseq from] Beta-lactamase GES-6 n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A088DDJ8_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8648AB ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFD -NEGLDLGLKVGIGSDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLSGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNMLSQESKL -KLKSWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWRENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium rhodesiae TaxID=36814 RepID=UPI0009F1D972 ----VEQRIADLEKRHNAFVGLYAQNLDSKVDL-AHRDGDPFAMCSTFKSYLSARVLQKAQ -AGELRLTDTMLVDPAELKPNSPRTEPNAGQPMAIADLCAAALQVSDNTAANMLLRTIGGP -PAITAFARSIGDDRTRLDRWETELNSAVPGDPRDTSTPRALGGGVARVLTGDVLDGPHRT -QLQDWMRANTT--SSMRGGLPAGWTTADKTGSGDFASTNDVGIAFGPNGERVLLAIMTRT -RSAQAEPLRQLIAEVATLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudodonghicola xiamenensis TaxID=337702 RepID=UPI00040728EF ----SAERLREIEQVLAARVGVFARNIDTGAEF-SHRAGERFAMCSTFKASLAALCLQRAD -RGELDLDERLSLNGVRLLPTSPVTSQQPPSGLDIRTLCKAIVERSDNTAANLLLDRVGGP -AAVTEFFREIGDDVSRLDRTEMALNANTQGDPRDTTAPEAMARTVERLALGTVLSEGARQ -QLVAWMRNEQNAKDRIRAAVPGSWTVANKPGTTPNGAANDIAALWSPNGPRFVLAIYIDT -RLDRLRPSVTAIRDVAQIALRH- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A2Z6TA99_BURVI -----RSELAALDKASNGRLGVAALDTSNGTRI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMNVLGGP -QAVTAFAHESGDTVFRLDRWEPGLNRAAPGAERDTSTPVAMVDTLQRLLLGDTLQQAQRT -QLTDWMTAGAPDATGIAAGVPPGSRVAAKRGTGGYGTTTEVAVVWPPSRAPIVLAGSFTQ -AQADAAARADVVASAARIAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012D8B6E9 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKTTSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDIKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLNMAERNQVIVEVGNAIFKEf ->[subseq from] ACI family class A beta-lactamase n=1 Tax=Selenomonas bovis TaxID=416586 RepID=UPI00036827FC -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTLKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=UPI00141ADE4D --------VADYETASGGHVGLYARNLTTGRAI-AWRADKRFVMCSTFKASLAACVLNQVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLRQVGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMALTIGRLTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG -GTPTEAQFKTLFSEVARGVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. Chr-9 TaxID=713612 RepID=A0A0B1RF66_9NOCA ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRANERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium mucogenicum TaxID=56689 RepID=A0A1A3GX92_9MYCO -------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK -AGQANLDAMVPITAADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF -QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAECVRSVL--- ->[subseq from] Class A carbapenem-hydrolyzing beta-lactamase GES-39 n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A346MLH3_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVGWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Class A beta-lactamase GES-34 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2I6PAY4_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRNEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A419TJC7_9BURK -------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLARLVRYTEKALVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP -AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA -QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA -PALAMPAREAVLREVGAAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus limnophila TaxID=210512 RepID=UPI000A031AB7 ---ALRRAITAVERSAGGPIGISLLDTHTGERF-GHRADDRFPLCSTFKLLLAARLLHGAD -KGQWAMTERLPVTKADMLFNAPFTEKRIGGTASLLELAQAMAVLSDNPAANIALAKVGGP -AALTAWLRSIADQTTRIDRNEPEMNNETPGDPRDTTTPAAMLATSRALVEGRILSPAARR -TLFGWMQASKTADTMIRAALPPGWQEANKTGAGSWRARNIVSVITPPGRKPIWVAAYLFA -ARSELAERNRQFVPLGRAIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2483-1-1 TaxID=2023148 RepID=UPI000B9C1449 ----AEQAYLELEARDTARLGVNALDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGKLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPKWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=A0A118Q0Q8_BURPY ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARSA -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QAVTAFAHGSGDTSFRLDRWEPALNTAAPGDERDTSTPLAMAESLRRLLLGDVLREPERT -QLTKWMLGNTSGFAGIRAGVPSDWRVAGVGGAGGYGTTTDVAVLWPASRAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. 360MFTsu5.1 TaxID=1172186 RepID=UPI0012DFAC03 -------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK -AGQANLDAMVPITAADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF -QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAECVRSVL--- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella holmesii TaxID=35814 RepID=A0A5Q1WZJ3_9BORD -------------------------------TT-GFRADERFALCSTFKVLAVGAVLARVA -RGEDDLSRPMRLSAADIVAHSPVTQQRLNEGMTLGQLCDAALVVGDNTAANLLLSTIGGP -PGVTAYARSLGDAVTRLDRLETALNDATPGDDRDTTSPVAMAENLRQLVLGDALPGPERE -RVRDGLLHCQTGKGRLRAGLPAAWTFGHRTGAGGHGTCNDIGIAWPPSAGPVVISAYLTE -SPLPLPERERVLAEAGRIVVH-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075AD78C ---AAQSQLDALEKASNGRLGVAALDTASGARI-GYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNTRSFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=A0A2J6U845_9VIBR ------KSIEKIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE -NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGSYGSRAITAMVWSENRAPLIISISLTE -TELTIQERDTVINEIGQLVFDAy ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-1477-1B TaxID=2022485 RepID=A0A260F898_9NOCA -----EQPYSQLEARDTARLGVSALDLTSGSLQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLRLTDTRTIAAEDKVPESAVD-WAPGSVVTLADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNLMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. 7MH5 TaxID=2547399 RepID=A0A4V1AZZ5_9BURK ---AAESPFADLERRNGGRLGVFAIDTGSGRTL-AWRADERFLMCSTFKGLLAAQILARID -AGQEHAERQVRYTEQDLIFTSPVTKAHVAHGMTVGALCQAAVEVSDNTAAILLMRSAGGP -QGLTQFVRGLGDSVTLSDRYEPHSNQY--SGALDTTTPRAIAQSARKILLGNVLSAQSRQ -QLEDWMIASTPGRARIRAALPADWRAGDRPGTSVERETNDYAIVRPPGRAPLVVAAYYDA -PGLDMARREDVLRDAG------- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. tessellarius TaxID=31965 RepID=A0A154V1B0_9MICO ---AADAAFTALEQRFGARLGVHAIDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADILAYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPTLNEAIPGDDRDTTTPRAAAALMRAYALGGPLDDDERA -LFTGWLTATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAPIVIAVHSSK -QQQDAVADDALVSGAANAAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia sp. TaxID=1884818 RepID=A0A352MR92_9ESCH ----LQAFLTQEETRLPGKIGMSIVNADGQPIF-GYRQNERFPLTSTFKVLACAALLDRLH -KNAGSLDQTVTINPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILTYLGGP -VAVTRFMRESGDTVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPLLTKPHQT -MLESWMREDKVANNLLRAALPKGWSIADKTGAGGYGSRAIIAAVYPTGEKPVYMAIYITQ -TDAEMKVSDGVIQKIGERVF--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A525HJQ7_SPHSX ----FTAAVRKLEQGLGARIGLHLIDPVGGRTA-TWRGGERFPMCSTFKLLLAGMILHKID -HGSERLDRQIAVPSTGILPNSPTTAGQAGGHLGIGDLCEAAMTRSDNTAANLLLGTVGGP -EGLTRFLRSTGDMVTRLDRVETILNEGTPGDPRDTTTPNAMLDTLRRLTFGTVLAPDSRK -NLMLWLANNTTGTEKLRKGLPAGWAIGDKTGAGGHNSNNDVALIWPPGRQPIFVTVFITG -GPDEAPARNPVHARIGELIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus fascians D188 TaxID=1051973 RepID=A0A165LRG1_RHOFA -----EKNYVELEARDSARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGMLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLTQASRQ -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQRILLVVLSAT -MSEDSPAMNALVADTTRMVVEQ- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00056BDF74 ---SAEQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00055D5304 ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPTGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ANPDAAAMNELVADAVREIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8554C4 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVDIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVVNEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. PsTaAH-137 TaxID=1305830 RepID=A0A327W6M8_9ACTN ---AAKDAFARLERTYRAHLGLYAIDTGNGREV-TWNDKRRFSYNSTVKSFLAAAVLKKNG ---SDGMDRVLHYDRADVIANSPVSEKHVDTGMSLRALCDAAVRYSDNTAANVLFKDMGGP -GRLGTFLKELDDRVTRTDRVEPFLSQWTPGERRDTSTPRQMAGDLRDLVLGDTLPTAERR -QLTTWLRNNTTGDTTIRAGVPKGWVVGDKTGTGYYGARDDIAVVWPPGRKPLVMAILTYR -DGKDTEADDKLLADAAKAAVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia anthina TaxID=179879 RepID=UPI000F80DD9C ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARSA -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QAVTAFAHGSGDTSFRLDRWEPALNTAVPGDERDTSTPLAMAESLRRLLLGDVLREPERT -QLTRWMLGNTSGFAGIRAGVPSDWRVAGVGGAGGYGTTTDVAVLWPASRAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] ACI family class A beta-lactamase n=1 Tax=Veillonella seminalis TaxID=1502943 RepID=UPI000F8F5492 -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLKWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9B7AC9 ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C82B3BE ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGEERFPMMSTFKTLACANLLYDFE -NEGLNLGLKVDIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00056447DE ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ADPDAAAMNELVADAVR------ ->[subseq from] Beta-lactamase n=2 Tax=Rhizobium/Agrobacterium group TaxID=227290 RepID=A0A1M3PNJ1_9RHIZ -----ELRLKELETRSGGRLGVAVSNTATGQIV-GNRLDERFAMCSTFKALAVAYTLHRVD -RGDEHLDRRVFFNERDLVTPFKATKPHLADGMTIEQLCEAAIIVSDSTAANLLLASFGGP -LALTTYLRSLGDRVTRLDKIELDLNVVKQGETHDTTSPRAMVGTLRQVVLGDALSAPSRM -KLTNWMTESKDATQRLRAGLPKGWQIANKPGTWKGISTNDIGVIFPPGRDPLVVAAYLGG -APGKIKDQETILADVARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. S6 TaxID=1479623 RepID=UPI00068AF637 ----AAQRLRELESRLEGRIGVHAFNSQTQVRF-GYRSTERFLFCSVGKVLVVSTILDRAT -SDPSLLSRNIDITEEDILPYAPATGQHIGESMSVESLCEAAITLSDNTAANLLVETVGGP -NAVTDFVRRTGDVLTRMDRTEPELNDA--AGELDTTTPAAFCSTLENLALGTALTPEHRL -RLTTWLKANTTGADQIRAGVPAGTTVGDKTGAGTHGESNDVAVIWPKNGSPVVLSIFTTS -SIADQAAQKSAIAEATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=BLAC_KITAU -----SGRLRALEKQYAARLGVFALDTGTGAGR-SYRAGERFPMCSVFKALAAAAVLRDVD -ARREFLTKRIHYTEKFVKDYIPVTGKNIAGGMTGAELCAAAVSESDNGAGNLLLRELDGP -TGITRFCRSLGDTTTRLDRWEPALNSAEPDRVTDTTSPGAIGRTFGRLIVGSALRAGDRK -RLTGWLVANTTNRPTFRAGLPDDWVLADKTGGGEYGVANDVGVVQPPGRAPLVLSVLSTK -FDPKGPTDNPLVAKAAALVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 06-418-1B TaxID=2022515 RepID=UPI000B9BF328 ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRSDERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ANPDAAAMNELVADAVREIV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-156-3 TaxID=2022517 RepID=A0A260DMU9_9NOCA ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ANPDAAAMNELVADAVR------ ->[subseq from] class A beta-lactamase n=1 Tax=Sulfitobacter geojensis TaxID=1342299 RepID=UPI000568C4B4 -------EIRALEKRHDARIGVMVRHPASGWHW-GHRENERFLMNSTFKSVLCAAILDQVD -RKALDLNAKIKISGQDILHYAPVTKKHIGSALPISDLCFATLDQSDNTAANLLINLLGGP -KGVMTYLDRINDAVTRLDRIEPSLNNFVAGDPRDTTSPAAMTTTWQKMLTGDALRPASRA -QLAEWMRHGSVTQEFLRKSAPAGWQIIDKSGGGRNHTRSYVAMITPLAGAPYFIAIYVSD -TPASWVERNAIVAGIGRAIID-- ->[subseq from] Beta-lactamase n=1 Tax=Komagataeibacter maltaceti TaxID=1203393 RepID=A0A2S3VYK9_9PROT -----PSVLSDYEHATGGHVGVCAHNIATGHKL-LWRADERFVMCSTFKASLVACVLSHVD -QGHDGLERVIPLTAADIQDYAPVAKAALAQGLSVGEMCEAAVEQSDNSCATLLLSRIGGP -SALTAFWRAMGDVTTRLDDPEPYLNRTPAGGVRDTTTPAAMAAIVQKLVLGTVLSASSRE -LLTRWMVGCQTGRNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPRPGTPIVICVYTRG -GTPTEQQFAALFSGVGRLVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycolicibacterium TaxID=2636767 RepID=UPI001323CFAE ----ASTEFADLEDRYQAIIGVYGVDVVSSATV-EHRPDERFALCSTFKAYAAARILQLSR -DGKVDLDASVRITAGDIVAYSPVVSRAVGSSLPLRDICAAALQQSDNAAGNIMLRTIGGP -SAVTDFARTIGDSQTRLDRWEPDLNTALPGDLRDTTTPRALCGGYRAVLVGDALRPSDRL -QLQQWMLANTTSTKRFRAALPSGWTSADKTGSGDYGSSNDVGLLSGPTGERVMLTVLIRS -RTKDSGLFDEAVAATARLALD-- ->[subseq from] Beta-lactamase n=1 Tax=Listeria rocourtiae TaxID=647910 RepID=A0A4R6ZSJ9_9LIST ---SVDKELKKLEEKYDVTLGVQGINLADNKQV-SYNEQERFAYASTYKAIAGGLLLKNLT ---EDQLNKRIKFSKEDLVDYSPVTEKHVEDGMTVKELINAAMMYSDNTAGNVLFDQLGGP -KGYQKELAKIGDKTTQADRIEPELNEAKPGDKRDTTTPEAMAKGLSFLATEGNMAANRLD -YFKQTLIDNTTGDKLIRAGVPDGYAVGDKTGAGSYGTRNDIAVIYPKGKKPLVWVIFSKK -AGKDDKYDDQLIADTAKVLSDFf ->[subseq from] Extended spectrum beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C8ZLL4_ACIBA ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGACANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio fischeri TaxID=668 RepID=UPI0012DAF0A6 ---SLTQNIEAIELSSGGYIGVSVLNTETNKTW-AYKGDQRFPMMSTFKTLACAKMLYDSS -VGGIDKYKITSITKEQIMPWSPVTEPLIGNMITTQKACEATMLMSDNTAANIVLNEIGGP -SSLTQFLRAMGDIKTRLDRIEPELNESKNGDKRDTTTPVAMSQTLNALLFGNTLNSQDEQ -TLKSWMMNNKVSDPLLRSILPNDWSIADRSGAGGFGSRGITAAIWNDKHQPIIISIYLTQ -TKLDMAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces caatingaensis TaxID=1678637 RepID=A0A0K9XAM5_9ACTN --------------QVPVRLGVFAYSPAGGTTV-EHRAGEAFPMCSTFKTLAVAAVLRDLR -QGDRFLHERVRYPRRDTEEYAPVTGRNLRDGMTGAELCGAAVSYSDNCAANLLLRRLGGP -GGVTRFCRSLGDDDTRLDHWEPALNSAVPGAVEDTTTPRAIALTYARLVLGNALPARHRE -RLTGWLLANTTGRNQLRAGLPRDWALGDKTGAGKYGTNNDVGVAWPPGRPPVVLSVLTTT -GDLDKTKTDVLIAETAALL---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02120-2 TaxID=2020327 RepID=A0A2M9KD91_9ACTN ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPMCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGRLLVGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMSVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] class A beta-lactamase n=2 Tax=unclassified Mycolicibacterium TaxID=2636767 RepID=UPI0012DF9D13 ----ASTEFADLEDRYQAIIGVYGVDVVSSATV-EHRPDERFALCSTFKAYAAARILQLSR -DGKVDLDASVRITAGDIVAYSPVVSRAVGSSLPLRDICAAALQQSDNAAGNIMLRTIGGP -SAVTDFARTIGDSQTRLDRWEPDLNTALPGDLRDTTTPRALCGGYRAVLVGDALRPSDRL -QLQQWMLANTTSTKRFRAALPSGWTSADKTGSGDYGSSNDVGLLSGPTGERVMLTVLIRS -RTKDSGLFDEAVAATARLALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. FA1 TaxID=1346710 RepID=UPI00128E09BC ---DVAAALADVEARHGVRLGVHALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- --GVAGVDERVPVEADDLVTYSPVAEQRVGVGMTWRELVGAALRFSDNTAGNLLLAGAGGP -AALTAWLRGLGDDVTRSDRTEPELNAYAPGDDRDTSTPRALAGTYRALVVGDVLGGPERD -LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTPAGAPVVLAVLSDR -ADPAAERADAPVAQAARVVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F577904 ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI0007542C75 ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 226 TaxID=2606611 RepID=UPI00130CC581 --------FEELEDRYQATIGVYAVDLESSATV-EHRTDERFSICSTFKAYAAARILQMAQ -AGHANLEAMVPITAADIVVNSPVLSQAVGSQMALREICAAALTQSDNAAGNIMLRTIGGP -SAITDFARSIGDSQTRLDRREPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALSGPGQF -QLQRWMSETATSTKRFRAGLPAGWTSADKTGSGDYGSTNDAGILIGPKRERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075FB41A ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacteriaceae bacterium 1482268.1 TaxID=1834080 RepID=A0A1A0MU39_9MYCO ------DRIEALQRRYQAKIGVYAVDLASGRTV-SHLDGESFAICSTFKAYAAARVLQMAQ -SRELSLDRPVFVDPVQAALNSPRTAPNAGGQMPLAELCAAAVQVSDNAAGNLLLQTIGGP -SAITDFARSIGDEQTRLDRWETELNSATPGDPRDTSTPNALGGGFRSLLAGDVLAPPQRQ -QLEEWMRANET--SSMRSGLPSGWTTADKTGNGDYGSTNDVGIAYGPGGEKLLLAIMTRA -QAEDAPNNRPLIGEVAAALV--- ->[subseq from] Class A beta-lactamase n=2 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0C5L1Y2_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] GES-1 n=22 Tax=Bacteria TaxID=2 RepID=D3U0R3_ECOLX ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sp. CBMA 226 TaxID=2606611 RepID=UPI0012DF8013 --------FEELEDRYQATIGVYAVDLESSATV-EHRTDERFSICSTFKAYAAARILQMAQ -AGHANLEAMVPITAADIVVNSPVLSQAVGSQMALREICAAALTQSDNAAGNIMLRTIGGP -SAITDFARSIGDSQTRLDRREPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALSGPGQF -QLQRWMSETATSTKRFRAGLPAGWTSADKTGSGDYGSTNDAGILIGPKRERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Mycobacterium TaxID=2642494 RepID=UPI000491F0AB -------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK -AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF -QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAECVRSVL--- ->[subseq from] Beta-lactamase GES-3 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q767E8_KLEPN ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=A0A2T4YM04_9SPHN --------VADYETASGGHVGICARNLTTGRAI-AWRADERFVMCSTFKASLAACVLDRVD -RGRARLADRIALVPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLRQVGGP -AALTAYWRRLDDDVSRLDDIEPFLNRTLPGGLRNTTTPRAMAATIGRLTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPQGWVIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG -GSPTEAQFKTLFSEVARGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8556DC ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPDDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMIGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C831654 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE -NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TKLTIPERDTVINEIGELIFDAy ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia sediminicola TaxID=458836 RepID=A0A495GZV1_9BURK -------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD -AGKEDPARLVRYTEKDLVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP -AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA -QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEQEANDYAIVRPPGRAPLLIAAYYDA -PALAMAAREAVLREVGAAFV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=S5YYN5_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGELVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050CB579 -----EQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVE-- ->[subseq from] GES-type beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2Z6FKN6_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKETEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase GES-18 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=H2ERK4_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALIFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sodalis praecaptivus TaxID=1239307 RepID=W0HZX8_9GAMM -----QPYLQKEENRLNARIGVAILDAHGQRIF-GYRSEERFPLNSTHKVLACAALLANAR -QHSALLEQHVTIMPQALVDYSPITQTRLAPGFTLRELCRAAVSYSDNTAANSILEVIGGA -GAVTRFMRLIGDNVTRLDRLEPSLNEAVPGDVRDTTTPASVVAALRTILATDVLTLPHRQ -LLQTWMMDDQVAGDLLRASLPTGWRIADKTGAGGYGSRSIIAAVYPDPKQPFYIAIYITQ -TAATLQQSNRVAANIGKIIF--- ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. PhB116 TaxID=2485174 RepID=UPI00105DFBEF ---DVADDLAALEAEFDARVGVSVVDTETGTTA-SHRADERFGYASSIKALAAAQLLHDVP ---AEQRDEVVTWTAADVEAYSPVTSEHVADGLTRAQLAEAAVRKSDNTALNIVLDRVGGP -AGLDQGLEDIGDTTTEVVNREPELNTIEPGSTDDTSTPAAFTADLGALLDGRWLDDPDRA -LLLDWMSGNATGDTLIRAGAPDGWVVADKSGGAG-GIRNDVAVVTPPGRAPVVVTVFTTR -NDPDARYDDALVARAAAIVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis ganjiahuensis TaxID=239984 RepID=UPI000592D0AE ----YAAEFEALEEEFDARLGVYALDTGSEAEV-AFRADERFGFLSTFKALLVGVVLSENS ---LEEMDRVVEYGEEDLVDHSPVVEENLGSGMSLMELSDATVRFSDNAAANLLLEEIGGP -EGFGESLVETGDEVTNPVRWETELNDVGPGDDRDTSTPEALVGSLEAFTLGDVLPEDRRE -VLVDLLVRNTTGDELIRAGVPEGWVVGDKTGGGG-GMRNDVAVVWPEEGDPIVMAVLTTR -NEEGVEFDNALIAEATEVVVE-- ->[subseq from] GES-type beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2Z6FKM9_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPKMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 283mftsu TaxID=1761810 RepID=A0A1H3XNM4_9MYCO -------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQMAK -AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF -QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAECVRSVL--- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A0E3TTK1_MYCCH ---------TALEDWYKARIGLYAIDLNSLTTI-EHRADDQFSMCSTFKTYAAARLLQLAD -AGAIDLNTKVAIASDEIVVDSPITRGEAGSSMSLGDICAAALIHSDNTAGNIMLRTIGGP -TAITAFAQSIGDSHSRLDRWEPDLNTAVPADPRDTTTPRALCTGYRQILTADVLAIQARD -RLLTWMRSNVTSSKRFRAGLPPGWTSADKTGAGDYGSTNDAGLLIGPAGQRVVVAVMTRS -RDQDAPPFNEAIAGAIRV----- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBAD86 ----VEDRLRELEIRSGGRLGVAVLDTATGRVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRIFFAEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSSTSRA -HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGR -ARGSVADQEAVLAEVARIIT--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A430G551_9SPHN ----WKSGMDRLREETGARIGLAVYDSGTGRRY-FDGAEARFAMCSTFKVPLAAAVLARAD -RGEIDLTRELRFSEADLLDYAPVVKANLAKGMSIEALLEAAVVMSDNAAANLVFGQISGP -RGLTAFIRSAGDTLTRSDRDEPTLNNVRNGEVRDTTTPQAMLWLLNALLLGETLAPASRA -KLIGWMEASPTGKDRLRAGLPKTWRVGDKTGTSGEGYVHDVAIATPPGRKPLLITCYMDA -PMLPAAKANAAHAKVGELV---- ->[subseq from] Beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=A0A149TNM6_GLUJA ---------SSYEEATGGHIGVFARNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD -QGKESLETVVPYTASDLGDYAPVAKANVAAGLSVRAMCQAAVEWSDNVCANLLLVRVGGP -AALTRFWRSLGDRQTRLDDWEPVLNRTPQGGLRNTTTPEAMAWILEHLVFGHALSGASCS -LLTGWMKNCQTGRGRLRAGFPPTWDVGDKTGNNGKDAAGDIAVAWPTREAPLIVCAYTRG -GQPNEKQFFEVFSEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=UPI00128DB341 --------ISQHENETGGHVGFYAENTQTGATL-GWRTDERFVMCSTFKASLAACVLARVD -KGLDTLERPLSYTAADIADYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRI -ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. OK889 TaxID=2135745 RepID=A0A4R7AAR7_9MYCO -------KFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMAN -ANQANLDAMVPITAADIVANSPVLSPAVGARMELREICAAALTQSDNAAGNIMLRTIGGP -SAVTDFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPKALCGGYRAILMGDALSGAGQF -QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLMRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] Beta-lactamase n=1 Tax=Listeria grandensis FSL F6-0971 TaxID=1265819 RepID=W7BK79_9LIST ---EANAELKKLEKKYDATLGVYGVNLEDNQKI-SYNEQERFAYVSTYKAIAGGLLLKNLT ---AEQLNKRVYFSKEDLVDYSPVTEKHVESGMTVKEIINAAMTYSDNTAGNILFHQLNGP -KGYQKELAKIGDKTTQADRFEPELNEAVPGDKRDTTTPEAMVKVLSFLVTKGNMASDRLD -YFKQTLIDNTTGDKLIRAGVPEGYAVGDKTGAGSYGTRNDIAVIYPKEKRPLVWIIYSKK -AGKDDEYNDQLIADAAKVLSNYf ->[subseq from] IBC-1 beta lactamase n=7 Tax=Gammaproteobacteria TaxID=1236 RepID=Q83ZP8_ECOLX ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=2 Tax=Ralstonia TaxID=48736 RepID=A0A0J9DYL1_9RALS -----LQAAKSEEAGLKARIGIAVIDKESGYTW-SYRGDEAFPINSTHKAYLCAALLEKVD -QRKLALSDITAISKSDLVTYSPITEKLQS--ATNAQLCEAAVSYSDNTAANKVLENIGGT -QGFNAFMRSIGDHKTRLDRNEPELNEGTPGDRRDTTTPIAAANSLNQIFFSDGLSRNAKA -ELTHWMVNDKVANDLLRKSLPPTWRIADKTGAGGYGSRSIVAVVYPEGKKPLLVSIYITN -TKATLGESNAAIARMGAVLFK-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf226 TaxID=1735691 RepID=A0A0Q4I0X3_9SPHN --------VAAYEAASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA -LLMLWLRQCRTGDARLRAGLPRAWVIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG -GSPTEAQFKSLFSEVARGVA--- ->[subseq from] Class A beta-lactamase GES-33 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1V0FXI3_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGACANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. UNC280MFTsu5.1 TaxID=1449048 RepID=UPI0005BBED4B -------RFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMDK -AGQANLDAMVPITAADIVVNSPVLSPAVGTRMELREICAAALTQSDNAAGNIMLRTIGGP -SALTAFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRALCGGYRAILVGDALPGAGQF -QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf226 TaxID=1735691 RepID=UPI000AEFF189 --------VAAYEAASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA -LLMLWLRQCRTGDARLRAGLPRAWVIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG -GSPTEAQFKSLFSEVARGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 15-649-1-2 TaxID=2023141 RepID=UPI000B9C0482 ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAVGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRFLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ANPDAAAMNELVADAVREIV--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A430CXP1_9SPHN ----WKSGMDQLREETGARIGLAVYDSGTGRRY-FDGAEARFAMCSTFKVPLAAAVLARAD -RGEIDLTRELRFSEADLLDYAPVVKANLAKGMSIEALLEAAVVMSDNAAANLVFGQISGP -RGLTAFIRSAGDTLTRSDRDEPTLNNVRNGEVRDTTTPQAMLWLLNALLLGETLAPASRT -KLIGWMEASPTGKDRLRAGLPKTWRVGDKTGTSGEGYVHDVAIATPPGRKPLLITCYMDA -PMLPAAKANAAHAKVGELV---- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=A0A2N7IDT3_9VIBR ------KSIEKIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE -NEGLDLGLKVDIESDDLIVWSPVTKHLIGKDLSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLTGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Class A extended-spectrum beta-lactamase GES-38 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A346MLH2_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGAQNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB107 TaxID=2485172 RepID=A0A3N1KC12_9MICO ---DVADDLAALEAEFDARVGVSVVDTETGTTA-SHRADERFGYASSIKALAAAQLLHDVP ---AEQRDEVVTWTAADVEAYSPVTSEHVADGLTLAQLAEAAVRKSDNTALNIVLDRVGGP -AGLDQGLEDIGDTTTEVVNREPELNTIEPGSSDDTSTPAAFTADLGALLDSRWLDAPDRA -LLLDWMSGNATGDTLIRAGAPDGWDVADKSGGAG-GIRNDVAVVTPPGRAPVVVTVFTTR -NDPDARYDDALVARAAAIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. CH28 TaxID=2512237 RepID=A0A4Z0N4Z5_9MYCO ----LADRIAALERRHNAFVGLYGVNLASGVTV-AHRDSDPFAMCSTFKAYLSARVLQQAQ -SGQLRLSDTVVVDPDLLRANSPRTEPNVGKPMALADLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDDRTRLDRWETELNSAIPGDPRDTSTPRALGGGIRSVLTTDVLDEPHRR -QLEDWMRANTT--SSMRAGLQPGWSTADKTGSGAYASTNDVGIAFGPNGERVLVAIMTRT -RSNDAPALRDLVAEVTTS----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromicrobium sp. IC_218 TaxID=2545468 RepID=A0A4R1ADT7_9ACTN ------DALRGLERRHDARLGLVAVDTGSGAVV-AHRADERFAHASTSKLLLAAAVLERRG ---VDGMQERVRVPT-ATVPHSPATQSRAGGTMTWSEVLDAALRLSDNTAANLLAEDVGGP -SGVTGVLRGWGDDVTRVDRLEPDLNTAEPGDERDTSTPRALAEHVRALVLGDRLPTDARD -RLVDRMRASTTGADLVRAGVPDGWTVADRSGGAAYGSRHDLAVVWPPEGAPIVLAVMTSR -DAEDAQGRDALVAEATRTAVD-- ->[subseq from] Class A beta-lactamase GES-27 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0S2EAE6_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEQEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=2 Tax=Vibrio TaxID=662 RepID=A0A2G1AT19_VIBSP ------KSIEKIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVDIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVFGNTLSQESKV -KLKNWMMGNKISDGILRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TKLTIPERDTVINEIGELIFDEy ->[subseq from] Class A beta-lactamase GES-31 n=2 Tax=Aeromonas caviae TaxID=648 RepID=A0A165EZV3_AERCA ----FKTDLEKLEREKAAEIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Shimia haliotis TaxID=1280847 RepID=A0A1I4F4N2_9RHOB ------AAVRDIERDLDARVGFYMHDTHSGQTL-AYAADDRFPLNSTFKLLACGALLGRAE -SGEVSLSQKVRLQDIEIVAYSPEIERRALTGVSLGAACEMTLAVSDNSAANIVLSAIGGP -DGLTGFLRSIGDQVTRLDRWETELNAAVPGDPRDSTSPRAIAFSVERLLLGDALTPASKA -ILREWLAGHRVADALFRAALPSSWEIEDRTGAGGYGSRSIVAVLYPPERAPIVVALFVTE -TEADFDRRNAAAAQIGAAIVAH- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00136968ED ------------------------------------------------------AVLKRSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDDTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] class A beta-lactamase n=1 Tax=Raoultella sp. 18102 TaxID=2681434 RepID=UPI00135C8FDC ---SVNAPFAELERRSGGRLGVFAHDLATGRHL-VHRPSERFLMCSTFKLLAVSAVLTRVD -KGSERLDRRIHFGREALLSHAPVTSLHADGEMTIGQLCDAAITVSDNTAGNLLLQAIGGP -DGFNYTMRAFGDTVTRLDRTEPTLNVA--SGVLDTTTPAAMGQVVGRLLSGRLLMPASVA -KLSDWLRGAKPGLTMLRAGLPADADVGDKAGRGTDGQNNDVAVVWKQGKKLLLVAAYYVN -SDMDDTQRNAVLAEVGRVVT--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL21I4N1 TaxID=1938801 RepID=A0A2S8S1L8_9BURK -----ESPIAGIERRYGGRLGLFAVDTGSGRTL-AYRADERFLMCSTFKGLLVAQVLARVD -AGKEKLERLVHYTERDLIFTSPITKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP -AALTRFMRDLGDTVTRSDRYEPESNQY--SGLLDTTTPRAIATSAARILLGDVLSHQSRR -QLEEWMVACKPGLNRLRAALPADWLAGDRPGTSVERETNDYAIVRPPGRSPLLVAAYYDA -PGVSMELRETVLREAGHVFV--- ->[subseq from] Class A beta-lactamase GES-29 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0S1Z1Y3_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEAEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura oligospora TaxID=111804 RepID=UPI00047BFD7E ---DVQQQLRKLETSYDGRIGAYAIDTGTGKTV-GYRTHERMPSNSTFKAILCGAVLNKAR -TDPGLMNRTFHWTKADVVEASPVTEKNIKNGLTAAQLCEATITTSDNTAANVLLKQVGGP -AAMTRYYRSLGDPTGRLDRYETELNIWSPGEKRDTIMPAFMARDLQRLTVGNSLAPEDRQ -QLITWMKATVTGDARIRAGVPKGWTVGDKTGTSNYAAADDIAIAYPPSGAPVIIAVYTHR -NVKGTPIDNRILAQTTTILL--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000F5F28C9 ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAMLWPTARAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=UPI00076A4F47 ---SLTENIEAIELSSSGTIGISVLNTATNTTW-NYKGDQRFPMMSTFKTLLCAQMLYNSS -DGILDKQAQTRITQEALIPWSPITEKQIGETITTEKACEATMLMSDNTAANIVLAEIGTP -SSLTLFLRFIGDNTTRLDRIEPALNEAKSDDIRDTTTPNAMTNTLNELLFGQTLNAKDKR -TLKAWMVNNKVSDPLLRSILPQQWFIADRSGAGGFGSRGITAIVWSEQRSPIIIAIYLKQ -TDLNIAERNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 32-65-25 TaxID=1970594 RepID=A0A258J683_9SPHN ----LRRAITAIERSAGGPIGISLLDTHTGERF-GHRANDRFPLCSTFKLLLAARLLHGAD -KGQWAMIERLPVTKADMLFNAPFTEKRIGGSASLLELAEAMAVVSDNPAANIGLARVGGP -AALTRWLRAIGDQTTRLDRNEPEMNNETPGDPRDTTTPTAMLATSRALVEGRILSPAARK -TLYGWMQASKTADTMIRAALPPGWQEANKTGAGSWHARNIVSVITPPGRKPIWVAAYLFA -AKSELAERNRQFVPLGRAIVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075B8C40 ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVASAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3D5AD7 ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---VDGMERAVPIEAADILEYAPVTETRVGGTMTLRELADAAMTRSDNTAAHLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDDDERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDIAVIWRSDAAPIVIAVHSAK -DQQDADADDALISGAAKAAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Thalassobius sp. I31.1 TaxID=2109912 RepID=UPI0013005318 ------DAIRSIERDLGARVGFYMHDTQTGEVI-AYAEDDRFPLNSTFKLLACGALLNRVD -NREANLTDKVRLRDFEFVDYSPALEAHSRAGVSLGTACGMMLSVSDNTAANIVLSAIGGP -EGLTDYLRSIGDQVTRLDRWETELNMAVPGDPRDTTTPRAIAQSAQDLILGDALEPASQA -TLRAWLADHRVADALFRAALPPSWSIDDRTGAGGFGSRSIVAVIYPPNREPIIASLFMTQ -TNADFDSRNTAAARVGAALVEH- ->[subseq from] class A beta-lactamase n=1 Tax=Shinella sp. UYSO24 TaxID=992418 RepID=UPI0011A142CC ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGR -ARGSVADQEAVLAEVARIIT--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aromaticivorans JS19b1 = JCM 16368 TaxID=1440774 RepID=A0A064CDZ8_9MYCO ----VEQRIAALENRHNAFVGLYAQNLNSKVEL-ANRDGDPFAMCSTFKVYLSTRVLQKAQ -AGELRLTDTVVVDPAELKPNSPRTEPNAGQPMAISDLCAAALQVSDNTAANMLLRVIGGP -PAITAFARSIGDDRSRLDRWETELNSAVPGDPRDTSTPRALGGGFARVLTGDVLDGSHRT -QLEDWMRANTT--SSMRGGLPAGWTTADKTGSGDYASTNDVGIAFGPNGERVLLAIMTRT -RSDDAEPLRQLIAEVATLVL--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T4E9_9BACT --eALSETVARIEEQLGARVGLSLMETGTGWSW-SHREDELFLMNSTVKVPVCGAILARWD -AGRLSLSDALPVRKADLVPYAPVTETRVGGNMTLDELCLAAIDMSDNVAANILIGHLGGP -EAVTQLFRSVGDPTSRLDRIEPKLNDFASGDERDTTSPAAMSETLRALLLGDVLSPEARG -KLAEWMRHGGVTGALLRAEAEDAWLILDKSGSGSH-TRNLVAVIQPEGGAPWIATMFISD -TDAEFEVRNEALKDLGRAVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C847E11 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPDDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWIIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter sp. 199 TaxID=2183923 RepID=A0A3D9PSZ0_9MICO ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLVAALLDRVG ---IAGMGRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAAYLRAYALGDPLDADERA -LFTGWLQATRTGATLVRAELPTDWTVGDKSGLGAYASRGDIAVIRRPDAAPIVIAIHSSK -DRQDADADDALISGAAKAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Tokpelaia sp. TaxID=2233777 RepID=A0A5M8P9U6_9RHIZ -------AIAGSEEKFQARIGIAVLDKAGGIIA-AWRAYEHFPLNSTYKPLLCAALLHKVD -KGALDLSDKVRFDKSRLVSYSPVTQNFITPAMDWRQLCRAAVEFSDNTAANLILAALGGP -GEFNRFLRNMGDNITQLDHFEPDLNHIKPGDKRDSTMPVAIGRTLQQLVFGDILQPQSRR -QLTQWLLNDKVADELLRSVLPPQWKIADKTGAGDYGSRSIISIIWPQKREPLLIAIYITA -TKASIAQTNAAIARIGKKIF--- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea sp. ATCC 55076 TaxID=1909395 RepID=A0A1U9ZY68_9ACTN ----VEEELRALEVAFEGRIGAYAVDTGTGRSV-AYRAGERFPLLSTFKAPLCAAVLCRAR -RERGLMGRRLRWRACDMTPNSPVTGRHLEGGLTVAELCAAAVTRSDGTASNLLMELIGGP -RGMTAFFRGLGDAVSRVDRWHPGLNEWVPGDERDTTTPAAMAGVLRALAVGGALHPEDRQ -RLVGWLLASQVGAGRVPAGLPAGWTVGHKTGTNSFGGGHDVAVVWTEAGAPIVMAVYTNR -TP-GLPTDDSVLARTAKVLVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum L-1 TaxID=690566 RepID=F6EYG4_SPHCR ---------KEIESESGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLSGAE -GNKFGLEGQIGFTKADLLDHAPVVKKNARRGMSMEELAAAAVEVSDNSAANLLLPMIGGP -EGFTRYVRAHGDNVTRLDRTEPALNENAEGDERDTTSPAAMAGLMRRLIFTD-LKPESAA -RLRGWLNASTTGGNRIKAGLPKDWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=A0A107TAU6_9BURK ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6VZU9_9FIRM -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASIRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFDPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRNPIVMAIMSRR -TEKNAKFDDAMIAEAAKRIFD-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. (strain SKA58) TaxID=314266 RepID=Q1NAL0_SPHSS ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR -PTIDAKKAEAAIAEAARAALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI00075BED39 ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTTWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia agricolaris TaxID=2152888 RepID=UPI0012917F40 ------VSLADVERRHGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLARVD -AGKDDPGRLVRYTEKDLVFTSPVTKAHVAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNRY--SGVLDTTTPRSITNSASKILLGNVLSPQSRT -QLEKWMTACKPGLNRLRAALPPDWVAADRPGTSVEEQTNDYAIVRPPGRAPLLIAAYYDA -PALGMPAREAVLREVGAVFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas adhaesiva TaxID=28212 RepID=A0A2A4IAQ1_9SPHN ------DPIAAYERATGGRIGVYARNVRTGKTL-SWRADERFIMCSSYKASLAAFVLARVD -RGEERLDALVAYSARDTVDWGPVAKENLARGMSVEAMCKAAVEISDGVCANMLMARSGGP -AALTAFLRSIGDATTRVDHYEPALDRVPSGGPDDSTTPAAMAATLEKVVLGDVLSDRSSA -LLTRWLVGNQT-NPRLRGGLPKDWRIGNKTGHSGRDMAGDIAVAWPTPDTPIVIAVYTRG -GTPREKQFDRAFAGIGRMIA--- ->[subseq from] Beta-lactamase n=1 Tax=Legionella adelaidensis TaxID=45056 RepID=A0A0W0R1T6_9GAMM --dELLKSIEKIENSTNARIGFFAINTANNTTL-HYRADERFPMGCTSKVIGVAAVLHKSM -HDENLLSKSIHYTKDDLTNWTPITEKNVNAGMSIQALCAAAISYSDNTAMNLLVKQLGGL -DEINGFARTLHNDSFRQDHNWPEEALSGGKDISDSSTPRDMARSVQRLVIGNHLNNYQKD -LLIQWLKANTTGDQKIRAGVPKDWVVGDKTGTGSYGTTNDIAVIWPPHCQPIVLAIYYTN -KNKKAPIRNDIVASVTKMVIQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea indica TaxID=1581193 RepID=UPI000C7A5604 ---DIRAEFRKLETAYQGHIGAYAIDTGTGRTV-GNRAHERFPSNSTFKAILCGAILHKAR -TDPGLMERTLKWKATDVVAHSPVTKENIENGLTPERLCHATITTSDNTAANVLLKQIGGP -AGMTRYYRSLGDPVGRLDRYETELNDWKPGERRDTIMPAFMARDLQKLTVGKALVPEDRS -RLIGWMKDSTTGRERILAGLPKGWTVGDKTGTGGYGTASDLAIAWPPSGAPVIIAVYVRR -GVADAQVDNGTIAKATSLLV--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacillus wiedmannii TaxID=1890302 RepID=A0A2A8MRI6_9BACI -----NQSFAKLEKEYDAKLGIYALDTGTNQTV-AYHSDDRFAFASTSKSLAVGALLRKNS ---LEALDQRITYTHEDLSNYNPITEKHVNTGMTLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPGETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAII---------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D17CDCA ---NIDSAIKQAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITQGMMDKTYPVTAEAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium sp. GB-1 TaxID=2022111 RepID=A0A2T3LNL5_9GAMM ----VNSAIEHAEKQLGARIGVSVVDGKGKQLF-GYNSDQRFPLMSTFKTLACAKLLHDNQ -INDGMMDKTYLINADTILDYAPVFQDKVGTEVSLKDACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDNVTRLDRIEPLLNEATPGDERDTTTPYAMNKTISNLVLGNALNASSKQ -QLKDWMKANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDKEIAQIGQAILQHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JGN2_ECOLX ---------------------------------------------------AAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAG------- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter pasteurianus TaxID=438 RepID=UPI000553618C ----------SYENATDGHIGVFAQNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD -QGKESLETFVPYTASDLGDYAPIAKANVGAGLSVRAMCEGAVEWSDNVCANLLLARVGGP -AALTRFWRSLGDHETRLDDWEPALNRTPPGGRRNTTTPAAMAGILRQLVFGHVLSETSCS -LLTGWLKNCHTGGSRLRAGFPSTWAAGDKTGNNGKDAAGDIAVAWPKPEAPLIVCAYTRG -GHPDEKQFFEVFSEIGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=A0A2T3QBD0_PHOAN ----VNSAIEHAEKQLGARIGVSVFDSKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADAILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNVLNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIAQAILQQf ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BL21I4N1 TaxID=1938801 RepID=UPI000CFCA5B7 -----ESPIAGIERRYGGRLGLFAVDTGSGRTL-AYRADERFLMCSTFKGLLVAQVLARVD -AGKEKLERLVHYTERDLIFTSPITKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP -AALTRFMRDLGDTVTRSDRYEPESNQY--SGLLDTTTPRAIATSAARILLGDVLSHQSRR -QLEEWMVACKPGLNRLRAALPADWLAGDRPGTSVERETNDYAIVRPPGRSPLLVAAYYDA -PGVSMELRETVLREAGHVFV--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia ammonioxydans TaxID=260086 RepID=A0A1I5FJ77_9PSEU --------LSDVEREFGRRIGVHASDTGSGAAV-AHRGDERFLLCSTVKALMAGFVLHRSV -TDPALLDRVVRWDRSEVLEYAPVTARHVDTGLTVAQLCEAAVTVSDNTAHNVLLREVGPP -AELTAWLRTTGDTVTRADRAEPALNEA--DGDRDTSTPAAFSATLAGLTTGAALPPAQRD -RLVGWLRAATTGSRQIRAAAPAGWQIGDKTGSGPGGEKNDAAILFPPDGAPIALTVFTVA -TDPDDDRGEEAIAAATRAAL--- ->[subseq from] Extended-spectrum beta-lactamase GES-15 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=D2KFE7_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKESEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Class A beta-lactamase GES-43 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A5B8KSP3_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKESEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase IBC-2 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q9AGN8_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQLAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=A0A1B2HPC8_9PSEU -----HDQLFALEQKFGARLGVFAGR--GDRTV-EHRADERFAFCSTFKGLVTAAVLDRDV -----PLDTVVRYTDADLMKSSQITRQHVATGMSLRDLCDAAVRYSDGTAGNLLLRTIGGP -AELTTYLRGLGDEVTRMDRWEPDLTSAVPDDPRDTSTPRALGTTYRKLVAE-------KQ -FLRDLMERNTTGGQRIRAGVPKDWKVADKTGTGDYGTMNDVGLAWPPAGEPLLISLMSSK -PTADAPYDQALLAEAAAYVIT-- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251YH76_9MICO ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---VDGMERAVPIEAADILEYAPVTETRVGGTMTLRELADAAMTRSDNTAAHLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDDDERA -LFTGWLKATQTGATLVRAELPADWTVGDKSGLGAYASRGDIAVIWRSDAAPIVIAVHSAK -DQQDADADDALISGAAKAAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia stagnalis TaxID=1503054 RepID=UPI000758367C ---AAQSQLDALEKASNGRLGVAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDASLLSRRTLYRRYELVPGSPVTDSRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNTRGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTARAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1P456_9ZZZZ ---ETLVKVKDAEDQLGARVGYIQLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGW------------------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea indica TaxID=1581193 RepID=UPI000C7AD9C7 ---QARKELRALEASFQGRIGAYALDTATGKTI-TYRAGERFPLLSTFKAPLCAAVLHKAR -TAPGLMGKHVTWTADDLTPGSPVTEKHVATGLTVAQLCAAATSVSDGTASNLLLREIGGP -AGLTRYFRTLKDPISRMDRFHPALNDWTPKDRRDTTTPAAIARDLRLLALGNALHPEDRE -QFVAWLLANRTGANRIRAGLPRTWTIGDRTGTNSFGGGNAIAVIWPDKGAPLVMAIYTNR -TP-GLPIDEKTIARTATILAD-- ->[subseq from] Beta-lactamase n=1 Tax=Hyphomonadaceae bacterium TaxID=2026748 RepID=A0A2E4S1Y6_9RHOB --------IEALELGHEGRFGGAAVTSGGEDLV-SHRADERFAMCSTFKWLMAGLVLQEVD -SGRETLERRVPIAGEDLVFHSPVTSQHVGAQLPVSQLCAATIGTSDNTAANLLLAGLGGP -DGFTQRLRASGDMVTRLDRMEPALNENEPGDPRDTTTPRAMARNLDRFLFGSQLSAPSRD -MLRTWMIAADTGLDRLRAGLPAGWTSGDKTGTSSNGANNDVAFSIPPDAKPLIIASYLNL -PDPVSPEANALHAKIAGLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium gallinarum TaxID=39689 RepID=UPI0013D4EB17 ---SIEASLQGLEQRHNAVIGLFASNLVSDKTV-AHRAQDPLALCSVFKGYASARVLQMAQ -HGELSLDEGMFVDPAQILPNSPVTGPRAGSEMTLAELCQATLQQSDNAAANLLLSRIGGP -QAITAFARSIGDGQTRLDRWETELNSAIPGDPRDTSTPEALGGGYRALLDGDVLAPPQRG -LLEDWMRANQT--SSMRAGLPPAWTSADKTGSGSYGTTNDVGIAYGPEGQRVLLAIMTRS -QANDAANMRPLIGEITALVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio tasmaniensis TaxID=212663 RepID=UPI0007EEF3F5 ------QSIEQIESRISARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISFSLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderiales bacterium C2 TaxID=2502236 RepID=UPI0010F79A86 ------APFATLEQKAGGRLGVAVLDCADGALI-GHRWQERFALCSTFKLPLAGVVLREAD -QGRLQLDRPLRYGLADMVPHAPVTGRHLASGMSIAALAEATQTTSDNVAANLLLRELGGP -AGLTARLRELGDGETRLDRYEPQMNVVHAGELRDTSTPLAMARTTDRLLNSDWLAPASRE -RLAQWMIATDTGLKRLRAGFPAGWKAGDKTGTFMDDKYNDVAIAWPPGRPPLIVSAYYEG -PGRHRDQDQAVLAEVGRLAAAW- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=A0A164PHL6_9NOCA ---TIDDDVAALEQRHGAQIGLWASDLTSGATA-SYRPRESFAMCSTFKPYAVAVALQFAS -RGLLNLDDAVPVTASDIVVNSPVLSTLIGGSITLSQACDAALTRSDNAAGNIVLRAIGGP -PAITAFARSVGDARSQLDRWEPELNEALPGDPRDTTTPESLAAGYRAILTGDALEKPHRE -RLVGWMRDTRTSDERFRAGLPLGWSSADKTGAGYYGSTNDAGLLFGPSGQQILVVVLTRS -HNQDASPLNEAIADTVRVTLSNf ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium sp. SKA34 TaxID=121723 RepID=Q2C377_9GAMM ----VNSAIEHAEKQLGARIGVSVLDGKGKQLY-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKPYQITADAILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLINSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNKSSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDKEIAQIGQAILQQf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. S1 TaxID=1641859 RepID=UPI00131BCAC2 -------PLADIERRNGGRLGVFAIDTGSGRTS-AHRADERFLMCSTFKGLLAAQVLSRVD -AGKEDPARLVRYTEKDLVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP -AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA -QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEEETNDYAIVRPPGRAPLLIAAYYDA -PALAMAAREAVLREVGAAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. MJM1172 TaxID=1703926 RepID=A0A1Q5AWM8_9ACTN ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPVCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGHLLLGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMAVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BD0F45 ------SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTENDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAMAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9125 TaxID=2184569 RepID=A0A3N8CGV6_9BURK ----AQSQLDALEKASNGRLGIAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDTSLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFARGSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sanxanigenens DSM 19645 = NX02 TaxID=1123269 RepID=W0AC30_9SPHN ---AVADPIAEYERATGGRIGVYALNVKTGTEI-AWRADERFIMCSTYKALLASFVLSRVD -RGQEELDSPVPYTAGDTLEWAPVANANLKKGMTVEAMCRAAVEISDGACANLVMARSGGP -SALTAFLRSIGDETTRVDHFEPALDRSPSGGPDDSTTPRAMATTLQALVLGTTLSAGSRA -RLTAWLMGNQT-NHRLRRGLPRRWRIANKTGHSGRDMAGDIAVVWPRPDTPILIAVYTRE -GTPTERQFDRSFGDIGRLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium DSM 44124 TaxID=1226753 RepID=A0A5N5VBM4_9MYCO -------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQIAK -AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF -QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAECVRSVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Listeria booriae TaxID=1552123 RepID=UPI00068BF7B6 ---QAKEALNQLEKKYGSELGVYAVNPENSQTL-QYNAQERFAFVSTYKAIASGVLLKNLT ---EQQLEKRVFFKKEDLVDYSPVTEKHVESGMTIKEIIHAAVAYSDNTAGNLLFNALNGP -KGFQDELRKIKDETTNSDRYETELNTAIPGDSRDTSTPEAFAKNLAFLTKQGNLQPKQLD -YFKQTLIENTTGDKLIRAGVPKGYIVGDKTGAGSYGTRNDIAVIYSDDKEPLVWVIFSKK -DKEDAEYDDQLIADAAKVLSRYf ->[subseq from] Beta-lactamase n=2 Tax=Granulibacter bethesdensis TaxID=364410 RepID=Q0BSY1_GRABC ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGKKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGE -ARGSVAEQEAVLVDVARIVTR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderia sp. Bp9126 TaxID=2184570 RepID=A0A3N8DN42_9BURK ---AAQSQLDALEKASNGRLGIAALDTASSARI-AYRSRERFPVCATYAVVAVAAMLARST -LDTSLLSRRTLYRRYELVPGSPVTESRADTGMTVGQLCEAVLQSDDKSAANLLMRVLGGP -QTVTAFAHDSGDTSFRLDRWEPALNTATPGDERDTSTPLAMAEALRRLLLGDVLREPERT -QLTKWMLGNARGFAGIRAGVPSDWRVASMGGAGGYGTTTDVAVLWPTSRAPLVMAVSFTQ -PDAGAAPHADVVAAAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. Leaf278 TaxID=1736319 RepID=A0A0Q6KQ02_9NOCA ---SAEQAYLELEARDSARLGVSALDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLSDTRTIAAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTQASRA -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSSAMNPLVADATRTAVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A270L936_ACIBA ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSPSKVMAVAAVLKQSA -PQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDK------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A2A5YW45_9SPHN ---------KEIEEETGGRLGVALVDRRGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMTMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFIRVHGDAVTRLDRNEPALNENAEGDPRDTTTPAAMAGLMARLFFQD-LKPDSAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGN-AYNDVALVKSPKGEEYILAIYLDR -PTVDAKKAEAAIAQTARAAL--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingomonas sp. MEA3-1 TaxID=1647414 RepID=UPI00065CAD1B ---------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTKSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] Class A beta-lactamase GES n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A110AZV8_PSEAI ----FKTDLEKLECEKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0C5X7Q2_SPHYB ---------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTKSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinokineospora sp. TRM65233 TaxID=2654637 RepID=UPI0012E99B29 --------LAELERRFDARLGVHATR--GARVV-EHRADDRFAFCSLFKALATAAVLARHP ---LSHLDDVIRYTRADLLDNARITPANVDSGMSVRALADAAIRHSDGTAGNLLLRDLGGP -AELTAYARELGDTVTRMDRVEPDITEATPGDPRDTTSPRAFGTSFSRVVLGDALPEDKRA -VLVDLLVRNTTGARRTRARVPAGWRIANKTGTGDYATANDVAVLWPPTGDPVTLAIMSSR -ADRTAERDEALVAEAAGLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C8600E5 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKSLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVATLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAIVWSETRAPLIISISLTE -TKLTIPERDTVTNEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Gemmobacter aquaticus TaxID=490185 RepID=UPI0011B46E11 ---ALEQTVSAVEAQLSGRVGIVVGQAGQDALW-SWRGDERFVMTSTFKVPLCGAVLTAAD -QGQLDLAQEIEIKPSDLIPHAPVTEQHLDAPMAIADLCMATIDMSDNTAANLLIKALGGP -EAVTDVFRSLGDSESRLDRYEPELNLAAEGDLRDTTTPLAMAHTLETLLIEDFLSANSRA -LLGEWMGKGGVTATLLRDKLPEGWTVYDKSGGGSD-SRSLIAVASTAGEAPWVISIYLAD -MEHDFATRNSALQSIAAAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium mucogenicum TaxID=56689 RepID=UPI0006B3316A -------SFEELEDRYQAIIGVYAVDLESSATV-EHRPDERFAICSTFKAYAAARILQIAK -AGQANLDAMVPITTADIVVNSPVLGPAVGARMPLRDICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPDLNEAAPGDLRDTTTPRALCGGYRAILVGDALPGAAQF -QLQRWMGETATSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGMLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAECVRSVL--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A149U0P8_9PROT --------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD -KGLDTLERPLSYTAADIADYAPVAKANLAKGMTIRGLCAGAVEQSDNTCANLLLAHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGSVLSAPSRI -ILTDWLIRCRTGEHRLRAGLPNEWKIGDKTGNNGKDAAGDIAVIWPTPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=A0A0Q4KEB2_9SPHN --------VADYETASGGHVGLYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG -GSPTEAQFKSLFLEVARGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=UPI000A439AC8 --------VADYETASGGHVGLYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMASTIGRLTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDIGLLWRDPDTPIIISVYTRG -GSPTEAQFKSLFLEVARGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. MJM1172 TaxID=1703926 RepID=UPI0009A16024 ----LAGALGELEREHSARLGVFARNTATGRTV-AYRADERFPVCSVFKTLAAAAVLRDLD -RDGEFLARRIRYTAEEAEKYAVVTGRNVANGMTVEALCAAAVSESDNMAANLLLRELGGP -RAITRFSRSLGDRITGLERWEPELNSAEPWRTTDTTSPRAIGTSYGHLLLGDALDPRDRE -RLTGWLLANTTNGERFRAGLGPDWILADKTGGGNYGVTNDVGVVRAPDGPPIVMAVLSTK -PGPEGPRDNPLVAKTAALLAQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mycobacterium sp. ENV421 TaxID=1213407 RepID=A0A2N8LFR6_9MYCO ----VEQRIAALEKRHNAFVGLYAQNLDSTVEL-ANRDGDPFAMCSTFKVYLSTRVLQKAQ -AGELRLTDTVVVDPAELKPNSPRTEPNAGQPMAISDLCAAALQVSDNTAANMLLRIIGGP -PAITAFARSIGDDRSRLDRWETELNSAVPGDPRDTSTPRALGSGFARVLTGDVLDGSRRT -QLEDWMRANTT--SSMRGGLPAGWTTADKTGSGDYASTNDVGIAFGPNGERVLLAIMTRT -RSAQAEPLRQLIAEVATLA---- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium brumae TaxID=85968 RepID=A0A2G5P4C1_9MYCO ------GRFAELEARHNALIGVYAANLDSGRVI-EERADESFAMCSTFKAYLAGRVLQLVE -RGQLTLEQRIFVDSRSIIMNSPVTKLHSGDFMTVAELCQAILQVSDNAAANLLLARVDGP -AGITAFARSIGDERSRLDRWETDLNAAAPGDPRDTSSPRALAGGFRELLTGEVLSVQRRR -LLEDWMRANQT--SSMRAGLPAGWASADKTGSGDYGSTNDVGIAFGPAGERLLLAILIRS -AGADPK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JVJ5_9ACTN --------FAALERKYKARLGLFAVATGTGATV-AYRPDERFAFCSTFKPLAAAAVLDRRP ---VSELEKRVRIRAADVNSISPITRKRIGSAMSLRELCDAAIRFSDGTAGNLLVRDIGGP -AALNAYLRRLGDPVTRMDDLEPELNRVGPGDPRDTTTPRAITADYRSLVLGDALPAAKRA -LLAGWLDRSVPGADRIRAALPPEWTIAHKTGTGDYGRAADVAVLRPPQGPPLVLGILSDR -EGYTTPPAGRLLAEAARLVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. AP50 TaxID=1884369 RepID=A0A1H7AH71_9SPHN ---------KTIEEETGGRLGVALVD-KSGALLlGFNRDERFAMCSTFKAPMAAAVLTGAD -AGKFGLSGEIPFGKDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDSVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMGRLFFNDM-KPESAD -KLRAWFNASSTGDNRIKAGLPTGWTSGSKTGTCGT-AYNDVALVKSPTGDEYILAVYLDR -PTVDAKKAEAAIAETAQAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI0003617916 ----VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPDDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium japonicum TaxID=332056 RepID=N1MPK8_9SPHN ---------KTIEEETGGRLGVALVDSKGALIL-GFNRDERFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPTLNENAPGDPRDTTTPAAMAGLMGRLLFRDM-QGASAD -QLRAWLNASSTGDKRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAIYLDR -PAVDAKAAEAAIAQAAQAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. RB68 TaxID=2585200 RepID=UPI001297AA8B ---EVTRRLRDLETAYKGRIGAFAVDTGTGRVV-GHRAHERFPFLSTFKALAAAAVLHKAR -TDPGLMERVVHWTEQEEKPNSPKTKGQGGPDMTVAQLCDAAIRYSDNTAGNMLLKQLGGP -AGYTRHLRSLGDPVSRLDRWEIELNDWKPGERNDTTTPANMGADLREVTAGGALVPADRA -RLVGWLRANTTGDARIRAGLP-HWTVGDKTGSAD-ARANDVAVAWPPGAAPVIIAVYTYR -HDLTAPREDKVIADTAAVLA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. YR768 TaxID=1884365 RepID=A0A1H9LMP1_9SPHN ---------KTIEEETGGRLGVALVD-KSGALLlGFNRDERFAMCSTFKAPMAAAVLTGAD -AGKFGLSGEIPFGKDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDSVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMGRLFFNDM-KPESAD -KLRAWFNASSTGDNRIKAGLPTGWTSGSKTGTCGT-AYNDVALVKSPTGDEYILAVYLDR -PTVDAKKAEAAIAETAQAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C823B30 ------QSIEQIESRISARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYNFE -NEGLNLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISFSLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=2 Tax=Pseudonocardia sp. AL041005-10 TaxID=445576 RepID=A0A0M3U972_9PSEU -------ALADVEREYARTIGVHVLDTGTGAAA-GHRDGDRFLMCSVVKALMAGFVLHRSL -SEPGLLDRPVRYGRADLLEYAPVTTRNLATGMTVGGLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGDGVTRADRSETALNDR--DGERDTSTPAALAATLRTLVLGDALPSAQRD -RLTGWLRANTTGDRQIRAAVPAGWTVGDKTGSGPLGERNDAGVLYPPDGAPLVLTVFTVP -ADADRARGEAAVAAAARAAI--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0H546_9SPHN ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR -PTIDAKKAEAAIAETARAALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-5630 TaxID=1463864 RepID=UPI0004CA7964 -----AAEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKYG ---LAGMDHVLRYDKKDLVANSPVTEKHVDTGMSRDALCDAAIRYSDNTAANVLLADLGGP -RALGALIRTTGDRVTRVERVEPLLSRWTPGETHDTTTPRQLTTNLRAYTLGDVLAAPERD -RLTGWLRANTTGDKTIRAGVPKGWTVEDKTGTGSHGARGDIAVIRPPGRAPLVLTLLSYR -DARTAEAEDQLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Schumannella sp. 10F1B-5-1 TaxID=2590780 RepID=A0A506Y8Z9_9MICO -haDIAVDLSALEQQYDARVGVVAIDTGTGRTA-SWHGDDRFAYASTLKALAAGLVLQRE- --GVAALDDPVAIPAAPLIDYSPVTEQHAGGTMTLGEVAAAAVELSDNTAGNLLFARLGGV -DALQKQLRGLGDRTTQVDRIEPDLNEAAPGDERDTSTPRALASSLRALAVDEPLDSVERA -ALNGWLDGSQTGATLIRAGLPDGWTAGDKSGAAGYGTRNDVAVVHPPSGAPIVIAVLSSR -DAPDAEYDDALVAAAARATLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. AD24 TaxID=1528693 RepID=UPI000B5F568C ----TESPIAEIERRYGGRLGVFAINPATGRTL-AYRADERFLMCSTFKGLLVAQVLARVD -AGKENLERLVRYTERDLIFTSPVTKANVAQGMSVGALCQAAVEVSDNTAAILLMRSAGGP -AALTRFMRGIGDSVTRSDRYEPESNQT--SGVLDTTTPRAIATSAARILLGDVLNPESRR -QLDAWMVACKPGLNRIRASLPADWLAGDRPGTSVERETNDYAIVRPPGRAPLLVAAYYDA -PGVSMELRETVLREAGHR----- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A149TXS4_9PROT --------ISQYENETGGHVGFYAENTKTRATL-GWRTDERFVMCSTFKASLAACVLARVD -KGLDTLERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP -SALTAFWRHLGDKTTRLDNVEPYLNRTPPGGIQNTTTPRSMAFILQHLVSGPVLSAPFRT -ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGEDAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DCF73FC ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK -ARGSVAEQEAVLVDVARIVTR-- ->[subseq from] class A beta-lactamase n=2 Tax=Paraburkholderia bannensis TaxID=765414 RepID=UPI00047F899C ---QTASPLADIERRNSGRLGFYAIDTGSGRTL-EHRADERFLMCSTFKGMLAAQILARID -AGKEQMDRLVHYTGQDLIFTSPVTKANVALGLPVHTLCQAIVEQSDNTAAVLLMRSVGGP -AALTQFMREIGDDVTRSDRYEPDSNRY--SGVLDTTTPQAIATAARKVLLGDVLSPQSRA -QLERWMIDCKPGLNRLRAVLPAQWQAADRPGTSIEEQTNDYALVRPPGRAPLLVAAYYDA -PGVSMEAREAVLREAGKVFVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0005EBA07D ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium abikonense TaxID=86193 RepID=UPI000787A76B ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRNEPTLNENAQGDPRDTTTPAAMAGLMARLFFRD-LKAESAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR -PTIDAKKAEAAIAETARAALN-- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657C1F5_9SPHN ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKEDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR -PTIDAKKAEAAIAETARAALN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. SBT000017 TaxID=1803385 RepID=A0A3M0HXP2_9NOCA ---TAEQTYLDLEARDVARLGVSAVDLASSTTE-SHRGDERFAFCSTFKVYAVGAVLAAVD -AGTLQLTDTRTITAEDKVPESAVDW-EPGSIVTIADLASAALTKSDNTSGNLLIREVGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTTRSRD -RLLGWMADTQTSDARFRAGVPDRWTSADKTGTGSFGVSNDAGLLLGPDGQKILLIVLSTT -TSEDSSAMNALVADATRTVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI00136577B4 ---AADAAFTALEGRFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDSTAANLLLEALGGP -AELDAALTAHGDDTTVVSRTEPDLNEAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLVRAELPADWTVGDTSGLGEYASRGDVAVIWRPDAAPIVIAVHSSK -DQQDADADDALISGAARAAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI0003746846 ----AEKQFAALEQRFDARLGVFAVDLGSEVTT-TYRADERFAFCSTFKVYAAGAVLAAAD -AGTLSLTDTRIVEAEDKVPESAIDW-EAGQVVTLEQLCVAALTRSDNTAGNLLIDAGGGT -GELTAFARSLGDAQFRLDRIEPDLNTALPGDDRDTTTPAGLAAGYRSLLTDGPLSNSSRA -TLLDWMAGTQTSDTRFRAGVPAGWTTADKTGTGSYGVSNDAGLLLGPDGRRILLVVLSRT -ANPDAAAMNELVADAVREIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D17523E ----IDSVIKQAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVTAEAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWVIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFDRy ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. RSMS TaxID=520734 RepID=UPI0010F9E426 ---------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTRSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVJ1_9BACT ---------------------------------------------------ACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDRWETDLNEAKPGDPRDTTTPKAMLADLQSLILENVLSRQSRE -QLARWMVANKTGDAKLRAGLPDDWRIGDKTGGGDYGTMNDVAVIWPPDREPLIISVYMTE -SEASFDDRNAAVADIGRAV---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ST-F2 TaxID=1490484 RepID=A0A1Q4UEX7_9MYCO -------SFEALEDRYQALIGVYAVDLASSATV-EHRADERFAICSTFKAYAAARILQMAK -DGKANLDAMVPITAGDIIVNSPVLSPAVGARMELREICAAALTQSDNAAGNIMLRTIGGP -SALTDFARSIGDSQTRLDRWEPALNEAAPGDLRDTTTPRALCGGYRAILVGDALSGAAQF -QLQRWMGETATSTRRFRAGLPAGWTSADKTGSGDYGSTNDAGMLIGPKGERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] Beta-lactamase n=2 Tax=Pseudonocardiaceae TaxID=2070 RepID=A0A1Y2MNV1_PSEAH ----------DVEREFGRRIGVHALDTGTGAAV-GHRDGERFLMCSVVKALTAGFVLHRSV -QDPGLLARPVRYDRSDLLEYAPVTEQHLATGLTVEQLCDAAVTVSDNTAQNLLLREAGSP -AELTGWLRGLGDEVTRVDRLEPALNER--DGDLDTSTPAALAATLGLLTTGDALPDAQRD -RLLGWLRGNTTGDRQIRAGVPQGWQVGDKTGSGPLGERNDAGVLFPPQGAPVVLSVFTVP -DDEEPDRGEAAVAAATRTT---- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DA7AB25 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGGK------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Photobacterium TaxID=2628852 RepID=UPI0013705C10 ---NIDSAIKQAEQQLGAKVGVSVLNGKGDALY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVAAEAILDYAPIFKDKIGTEVSLKEACFDTMTTSDNSAANFVLAQIGGA -AGVTKFLIDNGDNVTRLDRIEPLLNEAAPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTQWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TQATIPERDKAIAKIGRAIFQQy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 4M9327F10 TaxID=2502223 RepID=UPI0010F57785 ------SPLADIERRYGGRLGVFALDTGSGRTL-SYRADERFLMCSTFKGLLAAQILARVD -AGKENLARLVRYTEKDLIFTSPVTKANVALGMPVGALCQAIVEVSDNTAAILLMRSAGGP -AGLTRFIRGLGDTVTRSDRYEPESNKY--SGSLDTTSPKAIATLANRILLGDVLSPTSRA -QLETWMVAARPGLNRIRAALPADWQAADRPGTSVEEETNDYALVRPPGRAPLLIAAYYDA -PGVSMDAREAVLREAGAAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0009BB3D05 ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] SGM family class A beta-lactamase n=2 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657CG29_9SPHN ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKDDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR -PTIDAKKAEAAIAETARAALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI0011D13000 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIALGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK -ARGSVAEQEAVLVDVARIVTR-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD48533 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLTDGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK -ARGSVAEQEAVLVDVARIVTR-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sp. P1-5 TaxID=2024617 RepID=A0A5A7ZCW6_9MYCO ----VDQRIGALEKRYNAFVGLYARNLGSDAEL-AHRDGDPFAMCSTFKTYLSARVLQKAQ -AGELRLTDTELVEPADLKPNSPRTEPNAGKPMALSDLCAAALQVSDNTAANMLLRVIGGP -PAITAFARSIGDDRSRLDRWETELNSAVLGDPRDTSTPRALGGGVARVLTGDVLDLPHRK -QLEDWMRANTT--SSMRGGLPPGWTTADKTGSGDYASTNDVGIAFGPNGERVLLAIMTRT -RSAHAEPLRQLIAEVATLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium sp. GB-56 TaxID=2022106 RepID=UPI000D181C8A ----VNSAIEHAEKQLGARIGVSVVDGKGKQLF-GYNSDQRFPLMSTFKTLACAKLLHDNQ -INDGMMDKTYLINADTILDYAPVFQDKVGTEVSLKDACFATMTTSDNLAANLVLSHIGGP -VGVTTFLIDSGDNVTRLDRIEPLLNEATPGDERDTTTPYAMNKTISNLVLGNALNASSKQ -QLKDWMKANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDKEIAQIGQAILQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudokineococcus lusitanus TaxID=763993 RepID=A0A3N1HRC3_9ACTN ---QVAERLAALEEDFDARLGVMALDTGSGAVV-EHRADERFAAASTLKAFSAAAVLDGD- ----ADLDRVVTWGTGDLVTSSPVTEQHVDDGLPLREVARAAAQDSDNTAANLLYDELGGP -AALQDWLRDLGDTTTRADRPEPGLNDVGPGDERDTSTPRALAGTLERVLLGDALAVDDRE -LLDTWLRGTTTTSALVRAGVPDGWVVADKSGAAAYGTRDVVAVVRPPDRAPLVLALMSDR -RDEDAAYDDALLAAATEVVVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L6C492_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGGK------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D1581F4 ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum TaxID=46429 RepID=A0A081RIC4_SPHCR ---------KEIESESGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLSGAE -GNKFGLEGQIGFTKADLLDHAPVVKKNARRGMSMEELAAAAVEVSDNSAANLLLPMIGGP -EGFTRYVRAHGDNVTRLDRTEPALNENAEGDERDTTSPAAMAGLMRRLIFTD-LKPESAA -RLRGWLNASSTGGNRIKAGLPKDWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00055CB5CA ---SAEQNYLELEARDTARLGVSVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAALAAVD -AGRLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT -TSEDSPAMNPLVADATSAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 15-649-2-2 TaxID=2023140 RepID=A0A260R1W7_9NOCA ---SAEQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARALGDTEFRLDRAEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Henriciella algicola TaxID=1608422 RepID=A0A399RJB4_9RHOB -------PLAGLERESLGEFGVVALEVGGRERL-SHRADERFAMCSTFKWLLGALILRDAD -RDTGLLDRRIAISDADLVFHSPVTRQHVGSALSVSELCAATIKTSDNTAANLLLAGLDGP -EGFTQRLRDLGDTVTRLDRLEPELNENAPGDPRDTTTPRMMAHHLSDFLFGDRLTPSARD -TLRGWMIAADTGLDRLRAGLPEKWVSGDKTGTSSNRANNDVAFAIPPEGKPIVIASYINV -PNPVSKEANRLHAQIAKLA---- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657BXG5_9SPHN ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKDDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTTPAAMAGLMARLFFRD-LKAESAD -RLRAWFNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGEEYILAIYLDR -PTIDAKKAEAAIAETARAALN-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Ant20 TaxID=104605 RepID=A0A0A6CYV4_9SPHN --------VADYETASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLDGVD -RGRFRLADEIALVPADLQDHAPVARQNLARGMSLGEMCRAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRLTRGPALSPSSRA -LLMLWLRQCRTGDARLRAGLPRGWAIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG -GTPTEAQFKTLFSEVARGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Ant20 TaxID=104605 RepID=UPI000FE142D6 --------VADYETASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLDGVD -RGRFRLADEIALVPADLQDHAPVARQNLARGMSLGEMCRAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRLTRGPALSPSSRA -LLMLWLRQCRTGDARLRAGLPRGWAIGNKTGNNGKDAAGDVGVLWRDPDTPIIISVYTRG -GTPTEAQFKTLFSEVARGVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia heleia TaxID=634127 RepID=UPI000693656F ---AAESPLADIERRRGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILARVD -SGAERLDRLVRYTETDLVFTSPVTKANVARGMSIDALCRAILVESDNTAAILLMRSAGGP -AALTRFVRDLGDTVTRSDRYEPDSNRY--RGLLDTTTPKAIATTVQRLLLGDVLSAGSRA -QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYDA -PGVGMDAREAVLREAGTAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D157CE6 ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITQGMMDKTYPVTAEAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium sphagni TaxID=1786 RepID=A0A255E1Z6_9MYCO ----LEQRIAALETRHNAFIGLYSRNLDSNLSV-MHRVDDPFAMCSTFKAYLSGRVLQKAQ -AGELRLTDTVVVDPDLLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDARTRLDRWETELNSALPGDPRDTSTPRALGGGVSTLLTGNVLDDVHRK -QLEDWMRANST--SSIRAGLPAGWTTADKTGSGDFASTNDVGIAFGPNGERVLLAIMTRT -QSANAPALRDLIGEVTTAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=A0A2N5JKI0_CARML --kTIDSNLKKLEKEYEATLGIYAIDTETNKTI-NYNGEQRFAFASTYKALAGGLVLDKFN ---WDELNQTIMIHQEDLVDYSPITEKYVGIGMPLKDIIGAAMEYSDNTAGNILFDQLGGP -VGFQKELEKLGDHTTESVRYEPELNDAIPGDRRDTSTPKAIALDLKKLTADKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDVLVDDKSGAASYGTRNDIAVLYPSNRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVSDYf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. EP60837 TaxID=1855519 RepID=A0A173KS26_9SPHN ---------RTIEQESGGRLGIALVDNKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAD -AGRFGLDGQVAFTQADILDHAPVVKANGKRGLSMAELAEAAVEVSDNSAANLLLPMIGGP -EGLTAFVRAHGDTVTRLDRTEPALNENMEGDPRDTTSPAAMASLISRLLFRDM-KAESAS -RLMTWLNASTTGDERIKAGLPPGWTSGSKTGSCGS-AFNDVALVKAPSGEQYVLAIYLDR -PTVDAKAAEAAIAQAARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. SG570 TaxID=2587113 RepID=UPI0014476772 ----VEDQLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRIFFGEKDLVMPFKATKPHIADGMTVEQLCEGAAIVSDSTAANLLMANFGGP -SALTAYLRSIGDQITRIDKTELTLNIVKPGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGK -ARGSVVEQEAVLAHVARIVTR-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A1B4LLH4_9BURK ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3Z8WWV4_ECOLX ----MTDFLRQQEQRLHARIGMAVVNAQGETVF-GYRQDERFPLTSTFKTLACAALLERLQ -KNGGSLDEQVTIPPDALLDYAPVTKNYLAPAISLRMLCAAAVSYSDNTAGNRILTYLGGP -DAVTQFMRGIGDHVTRLDRTEPTLNEATPGDARDTSSPQKMAAGLQKILTAPPLTPANRA -VLAQWMRDDKVGDALLRAALPKGWAIADKTGAGGYGSRAIIAAVYPPERPPFYVEIFITQ -TEASMK----------------- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. KJ006 TaxID=416344 RepID=I2DW12_9BURK ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. 66-54 TaxID=1895845 RepID=A0A1M3PT48_9SPHN ---ALRQALADLEGRAGGKAGVCVLDCRDGALA-GHRLDERFTMCSTFKLPLAALVLARMD -AGAIAPDATLPIGPADPVGHAPAVRAQLAEGMAVLELCEAAQTQSDNGAANILLRALGGP -PALTAFFRSLGDEVTRLDRYEPALNTSHDGDPRDTTTARAMARSLQAILTGTVLAPASRA -RLIAWMIATRTGLKRLRGGLPADWRAGDKTGTAAAGKANDVAICWHPRREPFIVTAFYET -AAGPQPEDDAVVAQIGRIAS--- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio logei TaxID=688 RepID=A0A1B9P2F9_ALILO ---SLNDTIIALEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLHDAD -KKIINKKTETAIAQKDLIPWSPITEKYVGKSISTEKACEATMLMSDNTAANIVLQQIGSP -SSLTAFLRLMGDSTTQLDRIEPTLNEAKKGDIRDTTTPIAMVNTINKLLLGNTLTTTDKV -TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWNEHRLPLIISIYLTQ -TDLTLAERNDIIVHVGSALFSHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter agglomerans TaxID=549 RepID=L0HP91_ENTAG -----------------GRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSEAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKAVGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGY------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3K7C8_PHOPO ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRASLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia sp. P2 TaxID=882856 RepID=UPI00030C9093 --------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVTKALMAGFTLHRSL -SDPGLLDRPVRYGRADLLEYAPVTNRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPAPQRD -RLAGWLRANTTGDRQIRAAVPAGWGVGDKTGSGPRGERNDSGVLYPPDGAPLVLTVFTVP -ADADEQRGEAAVAAAARAAVA-- ->[subseq from] Beta-lactamase n=2 Tax=Photobacterium angustum TaxID=661 RepID=Q1ZR52_PHOAS ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ -QLKDWMQANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] Beta-lactamase n=1 Tax=Vibrio harveyi TaxID=669 RepID=Q9REJ3_VIBHA ---KLNEDISAIEEHISGRIGVSVWDTQTDEHW-DYRGDERFPMMSTFKTLACATMLSDMD -NEKLDKNATAKVEERNMVVWSPVMDRMAGQTTRFEHACEAAMLMSDNSAAHIVLRSIWGV -AGGTSFLRSIGDKATRLDRFEPRLNEANPGDKRDTTTPNAMVNTLHTLLEGDALSYESRI -QLKIWMQDNKVSDSLMRSVLPKGWSIADRSGAGGFGSRGITAMIWKENHKPVYISIYITE -TDLSLQARDQVIAQVSQLILD-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis (strain ATCC 27551) TaxID=336203 RepID=A0A292ZFA8_SPHSA ---------KEIESATGGRLGVALVDSKGVLML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTRSDLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLVFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI00050C78D0 ---SAEQNYLELEARDTARLGVKVLDLATGSSQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRVLLVVLSAT -TSEESPAMNPLVADATRAAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf343 TaxID=1736345 RepID=A0A0Q5PRY3_9SPHN ---AVADPIADYERATGGRIGVHALNVRTGKTL-SWRADERFIMCSSYKASLAAFVLSRVD -RGEEKLDALVPYTAKDTLEWGPIAKANLARGMTVEAMCKAAVEISDGACANLLMARSGGP -AALTAFLRSIGDTVTRVDHYEPALDRVPSGGPDDSTTPAAMATTLRKVIVGNVLSDRSKA -LLTSWLVGNQT-NPRLRGGLPRSWRIGNKTGHSGRDMAGDIAVAWPRPDTPIVIAVYTRG -GRPSEKQFDKAFAGIGRLVAK-- ->[subseq from] Beta-lactamase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A094ZTL7_9PROT --------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD -GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT -ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKYAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus coprophilus TaxID=38310 RepID=A0A2X4X341_9NOCA ---ALDSRLAQIENQHKVRLGVLGHTPATGRVY-AHRGDERFAMCSTFKMYAAAGILRLES -LGKLSLDETVPVEPADIVVNSPVTTEHQGRVMTVGGLCEAALTRSDNTAANLLLRRLGGP -DTVTALARSVGDGATRLDRWEPELNEAGRGDERDTTTAVGLGTGCRELLVGAGLPPPQQR -MLTGWMRASLTSGKRIRAALPRDWTAADKTGGGLHGTVNDAGVVWSPSGNPLVLVVLSDS -TTPDVPIDDA------------- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000CB62220 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGDERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKELSLENACTATMAMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPDDVRDTTTPNSMVVTLNELVYGNTLSQESKL -KLKNWMIGNKVSDGILRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] Beta-lactamase n=1 Tax=Yangia pacifica TaxID=311180 RepID=A0A2U8HA55_9RHOB --eALSDTVARIEEQLGARVGVSLVDTGSGWSW-FHRGDELFLMNSTVKVPVCGAILARRD -AGTLSLSDALPVREVELVPYAPITETRVGGTMTLDELCLAAIDMSDNVAANILIGHLGGP -EAVTQFFRSVGDPTSRLDRLEPELNVFAPGDARDTTSPAAMSEALRALLLGDALSPQARG -QLAEWMRHGGVTGALLRAEAEDDWLILDKSGSGRH-TRNLVAVIQPEGEAPWIATMFVSD -TDAEFEARNAALKDLGGAVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Inhella inkyongensis TaxID=392593 RepID=UPI00110E413D ---AFSTAVAALEQQHGGRLGVALLDTASGAVS-GHRLDERFALCSTFKLLLAAEVLRQSD -QGRLRLHDWQAFGRTPWVPHAPVTQAHKKHGMVLGALAEATQKTSDNMAANLLLRRLGGP -AALTQALREQGDAVTRIDRWEPEMNRVPPGEVRDTTSPAAMARSAAHWVLGDVLKPASRT -RLQRWMKDTETGLDRLRAGLPEAWVVGDKTGTGLPDQINDVAVIWPPGRTPWVLSAYYAA -PAQGREDFKAVLAEVGRLA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=F4Y5N4_KLEOX -------------------------------------------MCSTSKVMAAAAVLKQSE -SNKEVVNKRLEINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDKTGAGDYGTTNDIAVIWPENHAPLILVTYFTQ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia sp. GAS332 TaxID=1882750 RepID=A0A1N6LTT4_9BURK -------PLADIERRNGGRLGVFAIDTGSGRTL-AHRADERFLMCSTFKGLLAAQVLSRVD -AGKEDPARLVRYTEKDLVFTSPVTKAHVAQGMSVGALCQAIVEVSDNTAAVLLMRGAGGP -AGLTQFVRSLGDTVTRSDRYEPESNKY--SGVLDTTTPRSITKSASQILLGNVLSPQSRA -QLENWMIACTPGLNRLRAALPPDWIAGDRPGTSVEEETNNYAIVRPPGRAPLLIAAYYDA -PALAMPAREAVLREVGAAFV--- ->[subseq from] Uncharacterized protein n=2 Tax=Streptomyces sp. HGB0020 TaxID=1078086 RepID=S2Y6B6_9ACTN -------------------------------------------MCSTFKTLAAAAVLRDLD -RHGEVLARRIHYTRDDLVDGAPITGKNLAHGMTVAELCDAAIRYSDNSAGNFLLRLLGGP -TAITRFSRSLGDRVTRLDRWEPELNSAEPGRRTDTTSPRAIGGSYARLVLGCALNAPDRA -RLTHWLLTNTTGDHRIRAGLPASWTVGDKTGSGSYGTTNDVAVAWTDDGDPVVVAVLSTK -RDQDAAWDDALLSGAAAIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Ax-1719 TaxID=2608334 RepID=UPI00141D8A1E ------SPLADIERRQGGRLGFYAIDTGTGRTL-EHRAGERFLMCSTFKGMLAAQVLARVD -AGKEQRERLVHYTAQDLIFTSPVTKANVARGLPVHTLCQAIVEQSDNTAAILLMRSVGGP -AALTQFMRGIGDSVTRSDRYEPDSNRY--SGVLDTTTPQAMATAARAVLLGDVLSLQSRA -QLERWMIDCKPGLNRLRAVLPAGWQAADRPGTSVEEETNDYALVRPPGRAPLLVAAYYDA -PGVSMDAREAVLREAGKVFVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=UPI000E75B8A2 -------PLADIERRNGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLARLVPYTEKDLIFTSPVTKAHVAEGMSVRAMCQAIVEVSDNAAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNKT--SGVLDTTTPRSITKTASQILLGHVLSPQSRA -QLESWMITCKPGLNRLRAALPPDWIAGDRPGTSVESETNDYAIVRPPGRAPLVIAAYYDA -PALGMHAREAVLREVGEAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio sifiae TaxID=566293 RepID=A0A2S7XC76_9GAMM ---SLTKSIEAIELASSGQIGVSVLDTSNNQSW-SYKGDQRFPMMSTFKTLACAQMLYNSS -NNLLDKDSLTRITKESIIPWSPITEKLIGETISTESACQATMLMSDNTAANIVLTKIGSP -TSLTLFLRLIGDNITRLDRIEPALNEAQKGDIRDTTTPNAMTNTLNELLFGQTLNTKDKR -TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWNNKRAPIIISIYLTQ -TNLDMASRNQVIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=2 Tax=Vibrio TaxID=662 RepID=A0A2K1CFC2_9VIBR ---DLTASLTEIERESTGRIGVAVIDTKDNKLW-NYHGHDFFPMMSTFKTLACAHMLYQVD -RGQIKTAKSIPVTKDDLVNWNPVTEHFVGSTMTLQSLCNAAMTMSDNAAANLVLKAIGGP -ESLTAFLQRNGDKATRLDDIEPQLNYVDIGSKRNSTTPLTMMKTIEKLTLGSVLSEQSKR -QLLLWMKANMVSDGLLRAVVPKDWQVADRSGGGVNGSRTYTGMIWRKNRDPIFIGIFVAR -TKKTVPELNKLVRTISVAVLEEf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2L1TH66_ECOLX ----------------------------------------------TFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQA-------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter sp. DE0047 TaxID=2584949 RepID=UPI0011A0C826 ----LQAFLKQEEIRLPGKIGMSIVNADGQPIF-GYRQSERFPLTSTFKVLACAALLDRLH -KTAGSLDETVTIKPDELLSYSPITKNYVAPAITLHTLCSAAVSYSDNTAGNSILTYLGGP -DAITRFMRESGDDVTRLDRTEPTLNEATPGDERDTSTPERMASGLHTLLATPRLTAPHRE -MLEQWMRDDKVADNLLRAALPEGWAIADKTGAGGYGSRAIIAAVYPKGAQPVYMAIYITQ -TDAEMKMSDGMIKRIGERVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. FMUSA5-5 TaxID=2720023 RepID=UPI00143B4F0C ---AVEEELRALEVAFEGRIGAYAVDTGTGRSV-AYRAGERFPLLSTFKAPLCAAVLCRAR -RERGLMGRRLRWRACDMTPNSPVTGRHLEDGLTVAELCAAAVTRSDGTASNLLMELIGGP -RGMTAFFRGLGDPVSRVDRWHPGLNEWVPGDERDTTTPAAMAGVLRALAVGGALHPEDRE -RLVGWLLASQVGAGRVPAGLPAAWTVGHKTGTNSFGGGHDVAVVWTEAGAPIVMAVYTNR -TP-GLPTDDSVLARTAKVLVR-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. EC080619-01 TaxID=1096856 RepID=A0A0P0SBG8_9PSEU ---------DGVEREFGRRIGVHVLDSGTGATA-GHRDGERFLMCSVVKALMAGFVLHRSV -ADPALLDRPVRWGRADLLEYAPVTSRHVDSGLSVAQLCEAAVTVSDNTAHNLLLREVGSP -ADLTAWLRSTGDGVTRADRYETALNDV--DGDRDTSTPAALAATLRALTTGDVLPSAQRD -RLVGWLRANTTGDEQIRAGVPDGWQVGDKTGSGPLGEKNDAGVLFPPQGAPVLLTVFTVP -ADPSAPDDDRGAAAVAAA----- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000E0E75A4 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMAGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATKDIGVIFPPNRPPIVVAAYLGR -ARGSVADQEAVLAEVARIIT--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00084A2EFB ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMGSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A252A7Z1_9PROT --------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVN -GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLAHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT -ILTDWLIRCRTGEHRLRAGLPSAWKIGDKTGNNGKDAAGDIAIIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Desertifilum sp. IPPAS B-1220 TaxID=1781255 RepID=A0A1E5QKA0_9CYAN --nQLRDRIEQISRTAQGQVGVTATVLETGESV-TLNGEQQFPMQSVYKFPIAMAVLSQVD -RGTLNLDRKVRVETRDFALHSPIRDQHPQGVLTLAELLKYMVSESDNTACDVLLGLVGGP -EVVTQYLRDLGINDMVVANTEREIGQDNAVQYRNSATPDAAVALLSRLHEGQGLSASSQA -LLLQWMTETPTGLKRIKGLLPEGTVVAHKTGTSGTAATNDVGLVTLANGRHLAIAVFVSD -STADQATREAAIAQIARAAWDRw ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH) TaxID=1219045 RepID=A0A086PCP3_SPHHM ---------RTIEEETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLMGAD -AGRFGLEGQVAFTDKDLLDHAPVVKANRKRGLSMEELAKAAVEVSDNSAANLLLPMIGGP -EGLTAFVRAHGDTVTRLDRLEPALNENTPGDPRDTTSPAAMAGLIGRLLFRDM-QAESAA -RLTGWLNASKTGDKRIKAGLPPGWTSGGKTGSCGT-AFNDVALVEAPSGERYILAVYLDR -PTGDAKAADAAIAEAARAALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. CNPSo 3157 TaxID=2654983 RepID=UPI00128E44CA ---AAESPLADIERRNGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGMLAAQILARVD -SGAERLDRLVHYTEKDLIFTSPVTKANVARGMSIDELCRAILVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--RGVLDTTTPKAIATTAQRLLLGDVLSASSRV -QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGHAPLLVAVYYDA -PGVGMNAREAVLREAGTAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. STIS6.2 TaxID=1379700 RepID=UPI000D1428DD --------VADYETASGGHVGLYARNLMTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILSQRIGGP -AALTGYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRLTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPQGWVIGNKTGNNGRDAAGDVGVLWRDPDTPIIISVYTRG -GTPTEAQFKTLFSKVARGVA--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132E1X6_BURVI ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia sp. ESNIH1 TaxID=1985876 RepID=A0A2S4QQX4_9ESCH ----LQAFLKQEETRLPGKIGMSIVNAEGQPIF-GYRQNERFPLTSTFKVLACAALLDRLH -KTAGSLNETVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILAYLGGP -EAITRFMRESSDTVTRLDRTEPTLNEATPGDERDTSMPERMASGLHTLLATPRLTPSHRT -TLESWMREDKVADNLLRAALPKGWTIADKTGAGGYGSRAIIAAVYPTGEKPFYMAIYITQ -TDAEMKVSDGVIRAIGEWVF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AEW013 TaxID=2572915 RepID=A0A560X3U2_9SPHN ---AVADPIADYERATGGRIGVYAVNVKTGKSI-SWRSDERFIMCSSYKASLAAFVLARVD -RGEERLDALVHYTAKDTLEWGPIAKANLAKGMTVEAMCKAAVEISDGACANLLMARSGGP -AALTTFLRSIGDGTTRVDHFEPALDRVPSGGPDDSTTPAAMAATLQKFVLGSVLSDRSKA -LLTRWLIGNQT-NHRLRAGLPTSWRIGNKTGHSGRDMAGDIAVAWPRPDTPIVVAVYTRD -GKPTERQFDKAFAGIGSLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=A0A3R7KZZ7_9BURK -------PLADIERRNGGRLGVFAIDTGSGRTL-AYRADERFLMCSTFKGLLAAQVLSRVD -AGKEDLARLVPYTEKDLIFTSPVTKAHVAEGMSVRAMCQAIVEVSDNAAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPESNKT--SGVLDTTTPRSITKTASQILLGHVLSPQSRA -QLESWMITCKPGLNRLRAALPPDWIAGDRPGTSVESETNDYAIVRPPGRAPLVIAAYYDA -PALGMHAREAVLREVGEAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Brucellaceae bacterium VT-16-1752 TaxID=2487907 RepID=A0A3P1UKE6_9RHIZ ----VEDRLRELEIRSGGHLGVAVLDTATGQVV-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDHATRIDKTELALNIVKPGETHDTTSPRAMVGTLQKIILGSVLSPSSRG -RLTAWMMASRDAAARLRAGLPEGWRIANKPGTWNGISTNDIGVLFPPDRPPIVVAAYLGR -ARGTVPQQEAILSEVARIVAN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. p52 TaxID=935199 RepID=A0A1B2UJI5_9NOCA ----VDERLREIKDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVRDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Lysobacter sp. A03 TaxID=1199154 RepID=UPI000696A07E ---DLSSDVAELEKSHSAKIGVALFD-KDGRFLgGHRANERFAMCSTFKLPLAALVLSRID -RGEENAERRLHYDSNMIVEYSPAAERYLPTGMTVLEAAQASVQLSDNGTANLLLREVGGP -PGVTRYFRDLNDLTTRLDRKEPEMSSNIPGDMRDTTTPTAMGKTVSHVLYGEALKPSSAS -LLKRWLIGNQTGDSTLRAGFPKDWVVGEKTGTCSNGGRNDIGFFAVDGR-EYVVAVYTTA -PSFTPEGRNELVASTARVI---- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium vermicomposti TaxID=529005 RepID=UPI00142265F7 -------NPREIEKETGGRLGVALIDSKGALLL-GFNRDDRFAMCSTFKAPLAAAVLMGAE -AGKFGLEGQVAFSKADLQDYAPVVKANMKRGMSMAELAEAAVEVSDNSAANLLLSFVGGP -EGLTAFMRSHGDAVSRLDRNEPDLNENAEGDVRDTTSPAAMAGLMARLIFQNM-QPDSAT -LLREWLNGSTTGDRRIKAGLPEGWTSGGKTGSCGT-AFNDVALVKAPSGEEYVLAIYLDR -PTVDAKAADSAIAEAARAA---- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia alni TaxID=33907 RepID=A0A2N0IFY7_9PSEU -------ALADVEREYARTIGVHVLDTGTGAAA-GHRDGDRFLMCSVVKALMAGFVLHRSL -SEPGLLDRPVRYGRADLLEYAPVTTRNLAAGMTVAQLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGGTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPPAQRD -RLTGWLRANTTGDRQIRAAVPAGWTVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP -ADADTARGEAAVAAAARAAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio sp. EL58 TaxID=2107582 RepID=UPI000EFC2970 ----VLETVEAIELSSSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLVCAQMLYNSS -NELLDKDALTRITKESIIPWSPITEKLIGETISTEKACEATMLMSDNTAANIVLAEIGTP -SSLTLFLRLIGDNITRLDRIEPALNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR -TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ -TNLDMASRNQIIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens DSM 20623 TaxID=1449336 RepID=A0A0R2HXT3_CARDV -----SLNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi subsp. mandapamensis TaxID=48408 RepID=A0A0N0V8Y6_PHOLD ---NIDSAIKQAEQQLGAKVGVSVLNGKGDALY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVAAEAILDYAPIFKDKIGTEVSLKEACFDTMTTSDNSAANFVLAQIGGA -AGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLILGDALNPASKA -QLTQWMKSNKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TQATIPERDKAIAKIGRAIFQQy ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. SA916 TaxID=1851207 RepID=A0A2K0XW19_9SPHN ---------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTRSDLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia phenazinium TaxID=60549 RepID=A0A1G8J1H6_9BURK -------PLADIERRHGGRLGVFAIDTGSGRTL-SYRADERFLMCSTFKGLLAAQILARVD -TGKENLARLVRYTAKDLIFTSPVTKANVSQGMSVGALCQAIVEVSDNTAAILLMKSAGGP -AGLTQFVRDLGDTVTRSDRYEPESNQY--NGVRDTTSPRAIVKLANRILLGDVLSPLSRT -QLESWMIAAKPGLNRIRAALPADWLAADRPGTSVEEETNDYALVRPPGRAPLLVATYYDA -PGVSMDSREAVLREAGTAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. 20006FA TaxID=2056888 RepID=A0A197BST8_9SPHN ---------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTRSDLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A5C7WNW2_9MYCO ----IEDRLVALEQKYDAVVGLYGADLDSDRTV-SHRDGDMFAMCSTFKAYLAARVLYGAQ -QGELRLDDTIVVNREALQPHSPVTEREVGRAVPLGTLCAATLQQSDNAAANLLLARIGGP -PTITAFARLIGDERSRLDRWEVDLNSALPGDPRDTSTPRALGGGIRTLLTGTVLDETHRR -QLDEWMRGNVTSARSIRAGLPAGWTSADKTGSGDYASTNNVGIAYGPAGERILLSIMTRT -RGPEAPALQPLIAEVTALVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D1679C1 ---QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium TaxID=165695 RepID=UPI0005619E6A ---------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE -GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDCD998 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRIFFGEKDLVAPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPVGWRIANKPGTWEGIATNDIGVIFPPNRPPIVVAAYLGR -ARGSVADQEAVLAEVPRIIT--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI001329F500 ----VDERLKEIEDRYAVRLGVVAQSPVTGRVH-THRADERFAICSPFKVYAAAAILRLEA -EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS -TTPDAP----------------- ->[subseq from] Beta-lactamase n=3 Tax=Sphingobium TaxID=165695 RepID=A0A081SXW0_9SPHN ---------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE -GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00084A2DE2 ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMGSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D160BA3 ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TQRIHLNKPVLVKQSDILGYAPITKDRVGTTMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia eburnea TaxID=1189126 RepID=A0A2S4M2A6_9BURK -------PLTDIERRHGGRLGVYAIDTGTGHTL-EHRADERFLMCSTFKGMLAAQVLARVD -AGKERLDRLVHYTAQDLIFTSPVTKANVARGLPVHTLCQAIIEQSDNTAAILLMRGAGGP -AALTQFMRGIGDDVTRSDRYEPDSNRY--SGVLDTTTPRAIATAARATLLGDVLRLASRE -LLERWMIDCKPGLNRLRAVLPAGWLAADRPGTSVEEQTNDYALVRPPGRAPLLVAAYYDA -PGMSMDEREAVLREAGKVFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus coprophilus TaxID=38310 RepID=UPI000A074D93 ---ALDSRLAQIENQHKVRLGVLGHTPATGRVY-AHRGDERFAMCSTFKMYAAAGILRLES -LGKLSLDETVPVEPADIVVNSPVTTEHQGRVMTVGGLCEAALTRSDNTAANLLLRRLGGP -DTVTALARSVGDGATRLDRWEPELNEAGRGDERDTTTAVGLGTGCRELLVGAGLPPPQQR -MLTGWMRASLTSGKRIRAALPRDWTAADKTGGGLHGTVNDAGVVWSPSGNPLVLVVLSDS -TTPDVPIDDA------------- ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis (strain G4 / LMG 22486) TaxID=269482 RepID=UPI000766E13C -----ESPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=A0A385LJH7_RHORH ----VDERLKEIEDRYAVRLGVFAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLES -EGSLRLDETFPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS -TTPDAP----------------- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium ahvazicum TaxID=1964395 RepID=A0A2K4Y8N9_9MYCO -------RLAELERQYDAYIGLFAADPGSGRTC-AHRDDDPFAMCSTFKVYAAARVLQMAQ -HGELDLQQPIFIDPAALLPNSPVTAPRAGNTVPLAQLCAAALQRSDNVAANLLLAQIGGP -PAITDFARSIADERTRLDRCEIELNTAIPGDPRDTSTPRALGTGVQNLLSGTVLGDAQRR -QLEQWMRDNVT--SSMRAGLPPGWTSADKTGTGDYGSTNDVGMVYGPAGQRALLSVMTRS -RSANADALRPLIVEVTKSVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=UPI0002E2F280 --------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD -GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT -ILTDWLIRCRTGEHRLRAGFPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi subsp. mandapamensis TaxID=48408 RepID=A0A2T3KVZ8_PHOLD ---NIDSAIKQAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVTADAILDYAPVFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDGLNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=A0A5Q4ZSB9_9GAMM ----VLETVETIELSSSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLACAQMLYNSS -NDLLDKDALTRITKESIIPWSPVTEKLIGETISTEKACEATMLMSDNTAANIVLAETGSP -KSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR -TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ -TNLDMASRNQIIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio lentus TaxID=136468 RepID=UPI000C846877 ------QSIEQIESRVSARIGIAVYDSATKQTW-SYKGNERFPMMSTFKTLACANLLYDFE -NEGLDLGLKVGIESDDLIVWSPVTKHLVGKDLSLENACTATMTMSDNTAANVVLTGVGGP -NGLTEFLRLAGDSNTRLDHMEPELNHARPGAVRDTTTPNSMVVTLNELVYGTTLSQESKL -KLKNWMMGNKVSDGMLRSILPNDWSIADRSGAGAYGSRAITAMVWSENRAPLIISISLTE -TEFTIQERDKVINEIGQLIFDAy ->[subseq from] class A beta-lactamase n=1 Tax=Kocuria sp. Marseille-P3598 TaxID=1926282 RepID=UPI001301FA70 ----AAQKLRDLETRLDGRIGVHAINTGTQVRF-GYRSTERFLFCSVGKVLAVSAILHRAA -SDSTLLTRHIPIAADDILAYAPVTSQHVGGSMSVEDLCHAAITVSDNTAANLLVEVCGGP -SAVTEFVRGAGDVVTRVDRTEPTLNDA--DADLDTTTPSAFCTTLGNLALESVLTPEHRL -RLTTWLKANTTGADQIRAGVPDGVTVGDKTGAGSHGESNDVAVLWPTKGSPVILSIFTVS -SHQDTALQKEAIAEATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. LB126 TaxID=1983755 RepID=A0A2M8QV02_9SPHN ---------KEIEAETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTKADLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP -EGLTRYVRAHGDMVTRLDRTEPALNENAEGDERDTTSPAAMAGLMGRLIFRD-LKPESAE -KLRGWLNASTTGGNRIKAGLPKDWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C0A9B8 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0008415508 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BFDC36 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=Q4QXY0_CARDV -----SLNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=A0A4R9CQ36_CARDV -----SLNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter pasteurianus TaxID=438 RepID=S6D146_ACEPA ----------SYENATDGHIGVFAQNLATGQRL-TWRENERFVMCSTFKASLAALTLLRVD -QGKESLETFVPYTASDLGDYAPIAKANVGAGLSVRAMCEGAVEWSDNVCANLLLARVGGP -AVLTRFWRSLGDHETRLDDWEPALNRTPPGGRRNTTTPAAMAGILRQLVFGHVLSETSCS -LLTGWLKNCHTGGSRLRAGFPSTWAAGDKTGNNGKDAAGDIAVAWPKPEAPLIVCAYTRG -GHPDEKQFFEVFSEIGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. WWJCD1 TaxID=2022519 RepID=UPI000B9A6465 ---SAEQNYLELEARDTARLGVNVLDLATGSTQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARALGDTEFRLDRAEPELNTAIPGDPRDTTTPNSLAAGYRSLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI001072C2B3 ------LNFEKLEKKYDATLGVYGLDTETNKVV-AYNEDQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGIPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] Uncharacterized protein n=1 Tax=Brachybacterium sp. P6-10-X1 TaxID=1903186 RepID=A0A1P8NIG2_9MICO ------AAFSALESRFSATLGLFALDTGSGTRI-EHRADERFGHASTLKALAAAAVLDSAP -----DLEIPIPVEAEDLVEYSPILQEQVGSTVTLREVADAAVRYSDNTAGNLLLAQLGGP -AGLEAALRAIGDRTTSVDRWEPELNEVSPGDVRDTSTPRALATSLQAFVLDGVLDADRSE -LLTEMLTTTTTGDTLIMAGALDGWEVGSKSGAAAYGTRNDLGIAWPSDRAPIVIAVMSHR -DAPDAEYDDRLVAEAAEVAFR-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Desertifilum sp. IPPAS B-1220 TaxID=1781255 RepID=UPI000903D0C4 --nQLRDRIEQISRTAQGQVGVTATVLETGESV-TLNGEQQFPMQSVYKFPIAMAVLSQVD -RGTLNLDRKVRVETRDFALHSPIRDQHPQGVLTLAELLKYMVSESDNTACDVLLGLVGGP -EVVTQYLRDLGINDMVVANTEREIGQDNAVQYRNSATPDAAVALLSRLHEGQGLSASSQA -LLLQWMTETPTGLKRIKGLLPEGTVVAHKTGTSGTAATNDVGLVTLANGRHLAIAVFVSD -STADQATREAAIAQIARAAWDRw ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis NBRC 101654 TaxID=749388 RepID=F7VAS9_9PROT --------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD -GGLDALERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT -ILTDWLIRCRTGEHRLRAGFPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DCF6C98 ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLADGMTVEQLCEAAAIVSDSTAANLLMASFGGP -SALTAYLRSTGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK -ARGSVAEQEAVLVDVARIVTR-- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. A511 TaxID=2231647 RepID=UPI000E0C04BB ---SLEQSLSKIEQEIKGQVGVAVIDTQSLNQW-SYNGNQRFPMMSSFKTLACAKVLYDVE -QKKLSLNQKVDVPESGLVNWNPITENFVGSKMSLQSVCAAAMLMSDNYAANLALEQIGGP -SGLTAFLREIGDQKTRLDRYEPELNYVEKGAENDTTTPTDITQTVKRLLTGDVLSTSSKT -QLQFWMTNNMFSDSLARAVLPQGWLIADRSGGGVNGSRALTAMIWKSDRKPLFIGIFIAN -SSSTLPEINQVVADISQLIFTQy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. 35-24ZXX TaxID=1545915 RepID=UPI0009DE8997 ---TFQTDLAAIEARSGGRLGVALLD-DAGRKVaGYRDDERFAMCSTFKLPLAAMVLEKAA -EGQWAMGDTLPVTDADMVAYAPYVEAQRAKSVTVEGAASAAVSLSDNAAANLLLDRLGGP -QGFTNWLKGKGDAVTRLDRREPELNENAVGDPRDTTTPSAIAETSRRLVLGKALPLGQQR -LLYRWMENTSTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTSEKGKRYTLAVYLDR -PTVKGDAASAIIADATRAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Isoptericola sp. PW21 TaxID=2607479 RepID=A0A2W5WQ62_9MICO ---ATAEAFAALEERFDARLGVHALDTGDGTVI-EHRADERFAFASTMKALAGGLVLDRTG ---PDGWDEVVRYGAEDLVTYSPVTELHVDEGMTVLELVRASITVSDNTAANLLLDRLGGP -QSLEAALHELLSPDVSVDRAEPDLNDWAPGSTQDTATPAAMAAALRETALGDALRPEARA -ALRDALRDSTTGDALIRAGVPDGWVVGDKSGAGGHGTRNDIAVVERPDAAPLVLAVYSNR -RTPDGEADPALVAEATRVVVD-- ->[subseq from] Beta-lactamase n=2 Tax=Aquimonas voraii TaxID=265719 RepID=A0A1G6WVT0_9GAMM ---SAEARLRALESG-AARLGVCVLDTASGAHF-GHRLDEHFALCSTFKLALAAACLREAD -HGRLDLSEVLPYAESDLLEWAPVTREHLAEGLSIGRLAQAAQEISDGTAANLLVRRLGGP -AGVTARIRDMGDSVTRLDRYEPDLGLVLSADLRDTTTPVAMAQLVQRITTGDLLQPDSRD -QLLGWMRNTRTGLYRLRAGLPEDWLTGNKTGTGRTNKCNDIAITVPPGRSPVVIAAYYDS -GEQVERRHEAVLAEVARIAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Archangium gephyra TaxID=48 RepID=A0A2W5T5D6_9DELT -----HKALTALENSVKGRIGVFMLR--GEKTF-AYRATSRFTYCSSFKWILAAAVLEASQ -RGELLLSQRVKFTKKDLLGHSPIVEAHLDAGMTVAQLCEATVTVSDNAAANLLAPLVGGL -AGLSAFVKKLGDTTTRFDRMEPFLNSNEPGDKRDTTTPEAMTRLLHTALTSKHLTTDSQT -QLFMWMNAATTGLGRIRAAVPKDWSCGDKTGTSGNGALIDVAVLRPPSGEPIYVSVFLNA -RGIEMDTGSEVIAKAARIVLA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1G5SAU5_KLEPN -----------------------------------------FPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIT--- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=A0A2G4WLK7_PHOLE ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVTAEAILDYAPIFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] Beta-lactamase n=1 Tax=Blastomonas fulva TaxID=1550728 RepID=A0A222X0U7_9SPHN ---AIARELAAIEARSGGRLGVALVGPDGHQLA-GHRADERFAMCSTFKLPLAAMVLENAH -KGRLSMADPLPVTDSDMVVYSPYVEAQRAKTVTVEGAASAAVSLSDNTAANLLLDRLGGP -QSFTAWLRGKRDSVTRLDRREPELNENALGDPRDTTTPAAMAETTRSLVVGNAMPVGQQR -LLYRWMENTSTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTAETGMRYTLAVYLDR -PAVKGDAASAIIADATRAVL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea polychroma TaxID=46176 RepID=A0A438M5S0_9ACTN ---ELDKTLQELEKSYDGRIGAVGIDLGTGKTV-GYRAGERFPFNSMFKVFACAAVLRKAR -TDPGLMNRVVRWKPAEMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP -RGLTEFFRTIGDRTSRLDRTEPTLTEWKPGEERDTTTPAAAAQTFAKLTTGKTLHSRDRA -RLVGWLKASLTGANRIRAGLPKDWMVGDKTGTGGYGTANDVAIVWPPESAPIILSVFTNR -NLDDTPHDDKVIASTATALVK-- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4TAU9_9PROT --------LSDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ -HDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA -LLHGWLTASPTGPNRIRAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALK-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderiaceae TaxID=119060 RepID=A0A1G5MDP0_BURVI ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMSSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3PZV0_PHOPO ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSATELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. Ae707_Ps1 TaxID=1885572 RepID=A0A1Q8KIE6_9PSEU ---------DGVEREFGRRIGVHVLDSGTGATA-GHRDGERFLMCSVVKALMAGFVLHRSV -ADPALLDRPVRWGRADLLEYAPVTSRHVDSGLSVAQLCEAAVTVSDNTAHNLLLREVGSP -ADLTAWLRSTGDGVTRADRYETALNDV--DGDRDTSTPAALAATLRALTTGDVLPSAQRD -RLVGWLRANTTGDEQIRAGVPDGWQVGDKTGSGPLGEKNDAGVLFPPQGAPVLLTVFTVP -ADPDDDRGAAAVASATRAA---- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9B2234 ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WDPGSVVTIADLAAAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTESSRK -QLLAWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000CDAEF51 --------------------------------------------------------TARFD -AGAEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter sp. SVU/SVIMS1 TaxID=1476168 RepID=W8SQG3_9GAMM -------------------------------------------MCSTSMVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 14-2496-1d TaxID=2023146 RepID=UPI000B9B17AB ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium llatzerense TaxID=280871 RepID=UPI0008DDFF39 -------RFEELEDRYQALIGVYAVDLESLATV-EHRADERFSICSTFKAYAAARILQMDK -AGQANLDAMVPITAADIVVNSPVLSPAVGTRMELREICAAALTQSDNAAGNIMLRTIGGP -SALTAFARSIGDSQTRLDRWEPDLNDAAPGDLRDTTTPRVLCGGYRAILVGDALPGAGQF -QLKRWMTETTTSTRRFRAGLPEGWTSADKTGSGDYGSTNDAGLLIGPKRERVMLTVLIRT -RTRDAGPFNEAVAESVRSV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0005F002E6 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLVRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. HH130629-09 TaxID=1641402 RepID=A0A0M4Q4B5_9PSEU --------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVIKALMAGFTLHRSL -SDPGLLDRPVRYGRADLLEYAPVTTRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPAPQRD -RLAGWLRANTTGDRQIRAAVPAGWGVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP -ADADEQRGEDAVAAAARAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6SHF8_9SPHN ---------KEIEAETGGRLGVALVDSKGALLL-GFNRDERYPMCSTFKAPLAAAVLVGAE -GGKFGLEGTIPFGKDDLIDNAPVVKKNLKRGMSMEELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDTVSRLDRTEPALNENVEGDPRDTTSPAAMAGLMARLIFND-LKPDSAA -RLRNWLNASSTGDHRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPGGDEYVLAIYLDR -PTVDAKKAEAAIAETARAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-469-3-2 TaxID=2022510 RepID=A0A259Y4U0_9NOCA ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus TaxID=1827 RepID=UPI00050CD281 ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D16CA3B ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPASWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=2 Tax=Listeriaceae TaxID=186820 RepID=A0A099W984_9LIST ---QVKAALEKLEKKYGATLGVYGMDMGGKQTI-SFNAEERFAYASTFKAIAGGILLKNLT ---DEQLNKRFTFSKEDLVDHSPITEKHVDSGMTMKELINASMTYSDNTAANLTLQQLGGP -KGFEKELVKIGDKTMKPVRFEPELNDAVPGDIRDTTTPEAMAKTFAYLLTEGNLPADRLA -YFKQTLIDNTTGATLIRAGVPAGYIVGDRTGAGSYGTRNAIAMIYPKDKKPLVWVIYSKK -TGKDDEYNDQLIADAAKVLSDYy ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. 06-418-5 TaxID=2022507 RepID=UPI000B9ACBF7 ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WEPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] Class A beta-lactamase n=1 Tax=Shewanella sp. Pdp11 TaxID=2059264 RepID=A0A2K8ZPL0_9GAMM ------QTVNEFER-QGWNIGVSVIENSSNNVY-LINGDERFSTNSTIKALACAIVLSEVD -KNAVSLDDAMMINEQDVVSHSPVMKEFIGKKVTLADACKATMTYSDNTAANFAIKKSGGP -EGITSFLRSMGDDITRADRYEPDLNTNPEGDLRDTSTANAMAANFNKLLLGNILSTQSKE -QLKDWMMGNKVADNMLRLVLPTGWEIADRTGANSYGARGIISMVWSESQQPLIISIYIKK -ENTAIEEREKVISEIGRVIFTEy ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. C100 TaxID=1207055 RepID=W1S8K9_9SPHN ---------KEIEEETGGRLGVALVDRQGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQIPFGSDDILDYAPVVKKNKKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFIRAHGDSVTRLDRNEPTLNENAQGDPRDTTTPAAMAGLMGRLFFRDM-SAQSAD -TLRAWFNASSTGDKRIKAGLPEGWTSGSKTGTCGN-AYNDVALVKSPAGDEYILAIYLDR -PTVDAKKAEAAIAETARAALN-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D170D3D ---NIDSAIKQAEQQLGAKVGVSVLNGKGDALY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVAAEAILDYAPIFKDKIGTEVSLKEACFDTMTTSDNSAANFVLAQIGGA -AGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTQWMKSNKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TQASIPERDKAIAKIGSAIFQQy ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium damselae subsp. damselae TaxID=85581 RepID=A0A0D8LF53_PHODD ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTAYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=W1W6T5_9STAP ------------------------------------------------------------- -------------------------------------------------ANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKNGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C0BD3D ------SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. HS-D2 TaxID=1384636 RepID=UPI0007D94ADB ----VDERLREIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRLDETLPIDPEDIVVNSPVTSEHQGRVLPIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDETTRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGAGLPAPQQR -TLLGWMRATTTSDTRIRGGLPPGWTSADKTDGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_67_30 TaxID=1797584 RepID=A0A1F8IBJ2_9PROT --------LSDLEARYGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ -RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA -LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI0009BF8F7A ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITQGMMDKTYPVTANAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BFB999 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A4JN42_BURVG ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=2 Tax=Caulobacterales TaxID=204458 RepID=A0A069J1Z2_9CAUL --------LNDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ -RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA -LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Micrococcales TaxID=85006 RepID=UPI00065FBA9A ----AAQKLRDLETRLDGRIGVHAINTGTQVRF-GYRSTERFLFCSVGKVLAVSAILHRAA -SDSTLLTRHIPIAADDILAYAPVTSQHVGGSMSVEDLCHAAITVSDNTAANLLVEVCGGP -GAVTEFVRGAGDVVTRVDRTEPTLNDA--DADLDTTTPSAFCTTLGNLALESVLTPEHRL -RLTTWLKANTTGADQIRAGVPDGVTVGDKTGAGSHGESNDVAVLWPTKGSPVILSIFTVS -SHQDTALQKEAIAEATRIVT--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HKW2_9BACT --eLLRTKIYGIIEKANGRVGAAIINLETLDTL-TFNDDHHYPMQSVFKFPLALAVLNEVD -KGNLSLNQKVHLKKEDLLPWSPLREKYPDGNITLSELLTYTVSISDNNGCDVLFRLVGGT -EKVNQFVHSLGISEMEIAANEEEMHREWDVQFQNWTTPSAMGQLLYKFVDDSILSNDSKD -FLWNIMVSTVTGPRRIKGQLPDGTIVAHKTGSSGAAATNDVGIVTLPNGKQYIIVVFVSD -SPDDENAREEIIAGIAKAAWDAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI00062128CE ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Asticcacaulis tiandongensis TaxID=2565365 RepID=UPI001126DB6E -------EISKIEEETGLTIGVHIAG---RSLFaGYRDYHRFALCSTFKWMLAATVLREVQ -QNRLGLDQMISFGKADLVPHAPVTEKYLADGLTVEQLCHAILVHSDNVAANLLLRQIGGP -EAVTQFCRDNGDTVTRLDRYETELNSNLSGDERDTTTPEAMSQLMQRVFTGESLSRSHTR -RIENWMRESQTGKAMIHAGAPENAVVADKTGRGANGAVNDVAIIRMPKYGPLFLSIYTTG -GTLTAEQHNAVIANLTTYIFK-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium tokaiense TaxID=39695 RepID=A0A378TN43_9MYCO ----------EAERRHQARIGLYALDLKTHKTI-AHRNHERFAMCSSVKTYVAARVLQKAE -RGELALTDSVVVHGADIVSNSPVTETWVGRSIPVADLCAAALQKSDNAATNYLLKAVGGP -PAITEFARSISDNETRLDRWETELNSAIPGDVRDTSTPQALGDGNRALLEGTALTLESRR -QLIEWMVANTT--SSLRPGMPPEWILADKTGGGGYGSTNDVGLGFGPGGQQVVLSVMMRS -ATPNADGFRPVMAEIAAVVMS-- ->[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. Leaf186 TaxID=1736293 RepID=A0A0Q5S2G7_9MICO ---EVEAALVDLESRYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD ---DADLDRVVTWTQADVDAYSPLTSQHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -AGLDAALAAQGDDVTDVVHTEPELNTPTPGSTADTTTPAAFTATLARITDGDWLAADDRA -TVRDWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVTPPAGDPVVISVLTTR -NDPAATYDDALVAEAARIAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Kocuria sp. HSID16901 TaxID=2419505 RepID=A0A3S1AVA0_9MICC ----AAQKLRDLETRLDGRIGVHAINTGTQVRF-GYRSTERFLFCSVGKVLAVSAILHRAA -SDSTLLTRHIPIAADDILAYAPVTSQHVGGSMSVEDLCHAAITVSDNTAANLLVEVCGGP -GAVTEFVRGAGDVVTRVDRTEPTLNDA--DADLDTTTPSAFCTTLGNLALESVLTPEHRL -RLTTWLKANTTGADQIRAGVPDGVTVGDKTGAGSHGESNDVAVLWPTKGSPVILSIFTVS -SHQDTALQKEAIAEATRIVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. SYSUP0004 TaxID=2494735 RepID=UPI0010101757 -----AAAFAGLESATGARLGVWALDTATGRTV-EHRADERFGLASTHKVLSVAALLAALR ---PGDLDAVVHWPEGDVVAHSPVTAGRGASGLTWREVAAAALVESDNTAANLVLERVGGP -AGLTGSLRAWGDTVTRSDRTEPALNEVAPGDERDTTTPRALATDVHALLLGDALTDEDRG -LLLGWMRASTTGTGLVRAGVPDGWVVADRSGTGSHGARNDVAVVHPPGGAPVVLAVLTRH -DDPDALPDDDLLARATEVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0005D3DEE0 ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTAYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] Class A beta-lactamase n=1 Tax=Roseococcus sp. SYP-B2431 TaxID=2496640 RepID=A0A4R0YGC1_9PROT ----AEAPLAALERREGGRLHVFALDTGSGRSL-AHRADGRVLMCSTFKALLGAAVLARVD -AGQESLDRRVAIRGEDLLAYAPVARAHAGAGASVAVLAEGMVGLSDNTAANLLLPGVGGP -AGLTRWLRGIGDPLTRLDRDEPGLNR--PSGEMDTSTPRQMAMTLRRILLGEVLAPASRE -RLEGWMAASPTGRARLRAGFPPGWPVADKTGTGES-WANVIALVRPPGRAPAVVASFYDL -ANAAGAKRDSVHREVGRIV---- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15 TaxID=1802170 RepID=A0A1G3KG28_9SPHN ---------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPELNENAEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAE -RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR -PTVDAKKAEAAIAETARAALE-- ->[subseq from] Beta-lactamase GES10 n=1 Tax=uncultured bacterium TaxID=77133 RepID=C6GC02_9BACT ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRTAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLCDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. RAC03 TaxID=1843368 RepID=A0A1B3MS40_9SPHN ---------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPDLNENAEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAD -RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR -PTVDAKKAEAAIAETARAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. BAL3 TaxID=391600 RepID=B4WBN9_9CAUL --------LSDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ -RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA -LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALK-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=A0A087NH71_9SPHN ---------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPDLNENTEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAE -RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAIYLDR -PTVDAKKAEAAIAETARAALE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB24 TaxID=2485204 RepID=A0A3N2HKE9_9MICO ---EVEAALTDLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD ---DAALDRVVTWTQADVDAYSPLTSEHVTDGLPLRQLAEAAVRQSDNTALNLVLTELGGP -AGLDAALAAQGDDVTDVVHSEPELNTLTPGSTADTTTPAAFTATLARVTDGDWLEADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAAKYDDALVAEAARIAL--- ->[subseq from] Uncharacterized protein n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3JWG7_PHOPO ---QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium tokaiense TaxID=39695 RepID=UPI000E1BFB59 ----------EAERRHQARIGLYALDLKTHKTI-AHRNHERFAMCSSVKTYVAARVLQKAE -RGELALTDSVVVHGADIVSNSPVTETWVGRSIPVADLCAAALQKSDNAATNYLLKAVGGP -PAITEFARSISDNETRLDRWETELNSAIPGDVRDTSTPQALGDGNRALLEGTALTLESRR -QLIEWMVANTT--SSLRPGMPPEWILADKTGGGGYGSTNDVGLGFGPGGQQVVLSVMMRS -ATPNADGFRPVMAEIAAVVMS-- ->[subseq from] class A beta-lactamase n=1 Tax=Diaphorobacter sp. HDW4A TaxID=2714924 RepID=UPI0014087F2D ---SFQQRLKVLEARSGGRLGLSVQVLGGQNSI-GYREDEMFPMCSTFKLLLAARILQLSQ -LGEFPLEQSLLYEKKELVAYSPETEKHADVDMTIRALCEAAVVLSDNTAANLLLNLQGGP -AGLTRWLRTVGDMRTRLDRIETDLNTAIAGDPRDTTTPRAMGKTALALLTDKLLTPGSQK -QLRDWLLASRTGDKRLRTGMPSDWKIGGKTGSGDNGTANEVSIVWSAQGAPMIVSAYLTG -AMVESEGRDAILAEVGRVVTDWy ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio diabolicus TaxID=50719 RepID=UPI0014287AA4 --aQLTQTIKNIENDWKGRIGVYAYDTEGDFTF-GYRDKERFPLCSSFKSFLSAAILAKSQ -ENLLNINTLIDFSDRELEYWSPITKENQKYGMTIGKLAQAALQYSDNGATNILLESIGGP -KGMNNFMQSIGDNNFRLDRWELELNTAIPGDIRDTSTPKSMATSLGNLSFGDVLNDTNRE -LFNNWLIGNTTGDNRIRAAADKSWIVGDKTGSCGYGAASDIAVIWREKSSPLVMAIYTHK -TDPTAKHNDKVIAEVADKTF--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A521MIJ7_9CAUL --------LSDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ -RDEESLDRAVAVTRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA -LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALK-- ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium toruni TaxID=1935446 RepID=A0A1T4URL0_9GAMM ---QLSLELTNIEQQLGGNVAVAIYNANTNKSW-SYHGEQRVPMMSTFKTLACADLLHQAD -AQLVSVNQPIMIKQSDILSYAPVTKNHVGTSMTLAQLCHATMLTSDNTAANLVLNNIGGP -QSVTQFIRTLDDKTTRLDRIEPNVNNVSATEQRDTTTPIAINSTLYRLLYGNALSEQARI -QLKHWMMENKVSKPLLRAALPAGWHIADRAGYDTYGSRGITAAVWQQDKQPIMISIYVTQ -TGKPITELNAAIAKIGQLIFTH- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BCC1885 TaxID=2562669 RepID=UPI001183CF43 -----DSPLADIERQHGGRLGVFAIDTASSRTL-AYRADERFLMCSTFKGLLAAQVLARVD -AGKERLDRLVNYTGKDLIFTSPVTKANVAQGMSVGALCQAIVEVSDNTAAILLMKSVGGP -AALTQFVRSLDDTVTRSDRYEPASNQY--SGVLDTTSPKAIIGAVSRILLGDVLSAQSRT -QLESWMIACKPGLNRLRASLPADWRAGDRPGTSIEAETNDYAIVRPPGRAPLLVAAYYDA -PHVSMDSREAVLREVGTVFV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075M4I6_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLIL------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0009BC0042 ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLDRIEPLLNEATPGDKRDTTTAYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] class A beta-lactamase n=1 Tax=Cellulosimicrobium cellulans TaxID=1710 RepID=UPI0009F43C1E ---DVADELAALEAAYDARVGVHAVDTATGDHV-EHRADERFAYASTIKALAAGVLLQGQP ---VSALDETLPVTAEDVEGWSPVTGSRVGTAMTVRELGAAAVSQSDNGAFNVLLRRIGGP -EALQAALVEAGDTTTLVDAWEPELNHFTPGDPARTSTPRALADGVAAFALGDALDPAVRD -VYVSWLTGSTTGDGTIRAGAPEGWTVGSKTGTAGYGSRNDVAVVWPPDGAPIVLAVLTDR -AGMDDEPDDALLADVTAVVLGAf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis ATCC 27551 TaxID=1208342 RepID=A0A5B8CFM9_SPHSA ---------KEIESATGGRLGVALVDSKGVLML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTRSDLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENVEGDERDTTSPAAMAGLMGRLIFRDL-APESAE -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTIDARAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. BCC1886 TaxID=2562670 RepID=UPI001182A047 -----DLRLSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLVAQILARVD -SGEEQLDRRVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP -AALTRFVRGLGDPVTRSDRYEPESNRY--RGVLDTTTPKAMTITARHLLLGDALSASSRA -QLERGMIDCKPGLNRIRAVLPSGWQAADRPGTSVESETNDYALVRPPGRAPLIVAVYYDA -PGVSMDEREAVLREAGMAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. 06-412-2C TaxID=2022487 RepID=A0A260AA52_9NOCA ---------LELEARDTARLGVNVLDFATGSTQ-SYRGDERFAFCSTFKVYAVGAVLTAVD -AGKLQLTDTRTITAEDKVPESAVD-WAPGSVVTIADLAAAALAKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSLAAGYRTLLDGDVLTEASRK -QLLEWMGDTETSTARFRAGIAPQWTSADKTGTGSYGVSNDAGLLFGPDGQRILLVVLSAT -TSEDSPAMNPLVADATRAAVQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D160537 ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVSAEAILDYAPIFKDKVGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] Beta-lactamase class A n=2 Tax=Frondihabitans australicus TaxID=386892 RepID=A0A495IIB4_9MICO ---ALRAALASLEMRDHERLGVSVAVAGTDEHF-SYRGGERFALDSTSKLFTATLLLRDDS ---DAQLAQTIHYTAADLQSYSPITSQHVDTGMSLRDVIAAALQYSDNTAANLMFEQLGGP -TAVERDVRALGDGVTTFDRIEPDLNTAVPGDRRDTTTPDEMAADVGRFTLGATLRPARRS -LLVDLMRGNTTGDADVRAVVPSGWIVADKTGSGGYATANDVALVTRPGAAPILIAVYTSG -TSADATTPDGIVADVARAALD-- ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus epidermidis TaxID=1282 RepID=A0A6A1Z9W6_STAEP ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYETELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Georgenia sp. ZLJ0321 TaxID=2483797 RepID=UPI000FDB9B7D ---DVTADLDALETEFDARVGVSALDTETGRSV-EYRAQERFGYASTLKVFAAAELLRQVP ---PGEWEARVVWTQEEVDAYSPVTSEHVDGGLSLAELAEAAVRESDNTAMNLVLDRIGGP -AGLDAGLAALGDETTDVVNNEPALNEIDAGDTRDTTTPAAFTADLHALLQPQNLAPDDRA -TLLDWMSGNPTGDALIRAGAPAEWVVQDKSGGAG-GIRNDIALVTPPGRAPIVITVMTEK -NDPAAEYEDELVARVAEVVIT-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDB47DC ----VEDRLRELEIRSGGHLGVAVLDTATGQVI-GNRLDERFALCSTFKALAIAFTLARVD -RGEEKLDRRVFFGEKDLVMPFKATKPHLTDGMTVEQLCEAAAIVSDSTAANLLMASFGGP -FALTAYLRSIGDQTTRIDKTELALNIVKSGETHDTTSPRAMVGTLQRIVLGSALSPTSRA -HLTEWMMASRDAAQRLRAGLPAGWRIANKPGTWEGISTNDIGVLFPPNRPPIVVAAYLGK -ARGSVAEQEAVLVDVARIVTR-- ->[subseq from] class A beta-lactamase SGM-2 n=1 Tax=Sphingobium japonicum TaxID=332056 RepID=UPI00031FB5C4 ---------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE -GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG -KLRGWLNASTTGANRIKAGLPKGWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI0011A5CEB6 ----VDERLKEIEDRYAVRLGVVAQSPVTGRVH-THRADERFAICSPFKVYAAAAILRLEA -EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR -TLLGWMRATTTSGTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS -TTGDPD----------------- ->[subseq from] Beta-lactamase n=1 Tax=Gluconacetobacter entanii TaxID=108528 RepID=A0A318Q1G2_9PROT --------LSDYEHATGGHVGVYAHNIATGRRL-LWRANERFVMCSTFKASLAACVLSHVD -QGRDGLDHIIPLTAADIQDYAPVAKAALAQGLSVGDMCEGAVEQSDNSCATLLLSRIGGP -SALTAFWRAMGDTTTRLDDPEPYLNRTPAGGVRDTTTPASMAAIIQKLVLGTVLSAPSRA -LLTRWLVGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPRPDTPIVMCVYTRG -GTPTEQQFAAVFSGIGRLVAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium japonicum (strain DSM 16413 / CCM 7287 / MTCC 6362 / UT26 / NBRC 101211 / UT26S) TaxID=452662 RepID=D4Z324_SPHJU ---------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE -GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG -KLRGWLNASTTGANRIKAGLPKGWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus sp. NM-18 TaxID=2675220 RepID=UPI0012E2B6C8 ----LRRAIPLIERSAGGPIGIALLDTSSGARF-SHRAQQRFPLCSTFKLLLAARLLHGAD -RKLWSMTDRLPIRREDMLFNAPFTEKRIGGTASLLELAEAMTVLSDNPAANLGLAHVGGP -AALTRWLGAIGDSVTRLDRNEPEMNNETPGDPRDTTTPAAMLATCRTLVTGRILSPAARA -QLFAWMQASKTADTMIRAALPQGWQEANKTGAGSWHARNIVSVITPPGRKPIWVAAYLFA -ARSELAERNRQFVPLGRAIVE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 28-64-96 TaxID=1970591 RepID=A0A258VBI7_9SPHN ---ALCRAITAVERSAGGPIGISLLDTHTGERF-GHRANDRFPLCSTFKLLLAARLLHGAD -KGQWAMSERLPVTKADMLFNAPFTEKRIGGSASLLELAEAMAVVSDNPAANIGLARVGGP -AALTRWLRTIGDQTTRLDRNEPEMNNETPGDPRDTTTPAAMLATSRVLVEGRILSPAARR -TLFGWMQASKTADTMIRAALPPGWQEANKTGAGSWRARNIVSVITPPGRKSIWVAAYLFA -GKSELAERNRQFVPLGRAIVE-- ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=4 Tax=Bacteria TaxID=2 RepID=A0A6D1U1F7_STAEP ---SHAQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYETELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio wodanis TaxID=80852 RepID=A0A090KI17_9GAMM ----VLETVETIELSRSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLACAQMLYNSS -NDLLDKDALTRITKESIIPWSPVTEKLIGETISTEKACEATMLMSDNTAANIVLAETGSP -KSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR -TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ -TNLDMASRNQIIVEVGNAIFKEf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. shizuoka-1 TaxID=2039281 RepID=A0A2C9T155_9MYCO ----IDQRIAALERRHNAFAGVYGQNLDSGQTV-TNRADDMFAMCSTFKAYLAARVLQKAQ -AGELRLTDTALVDPELLRANSPRTEPHVGTPMALSELCAAALQVSDNTAANVLLRVIGGP -PEITAFARSIGDERSRLDRWETELNSALPGDPRDTSTPSALGGGVRALLTGTVLDEPHRR -QLEDWMRANTT--SSMRAGLQPGWTTADKTGSGDFASTNDVGLLFGPAGERILLAIMTRT -QSDDAPGLRPLIGELTALVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A2W6XEU7_9CAUL --------LADLEARHGGRLGVAALDVGSQRRV-SWRGQERFPFCSTFKAFLAVAVLERVQ -RGEEQLDRAVPVVRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI -AVWRAWWPTFGDITTLISRLEPDLNTALPDDPRDTCLPDQTLANIRELAFSDRLTPEHDQ -MIQGWLTASPTGPNRIKAGAPQGWTVAHKTGTGVNGTANDIGVAFPVSGSPVVLATYFTG -ATASDDQRDAVIAEATRRVFK-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A103I4F7_BURVI ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSLDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J45 TaxID=935266 RepID=A0A562D6J2_RHORH ----VDERLKEIEDRYAVRLGVVAQSPVTGRVH-THRADERFAICSPFKVYAAAAILRLEA -EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDGTTRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR -TLLGWMRATTTSGTRIRGGLPSGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLVILSDS -TTGDPD----------------- ->[subseq from] class A beta-lactamase n=2 Tax=Vibrio cholerae TaxID=666 RepID=UPI000E6B89A0 --dNLTQAVTKIESDWQGRIGVFAYEVNGDFRF-GYREAERFPFCSSFKAFVAAAILTQSQ -NELIDLNNIVDFKNRELEFWSPITEKYRYDGMTIGQLAKASLQYSDNGATNILLERIGGP -EQMTYFMRNLGDSVFRLDRWELDLNTAIPGDNRDTSTPYAMASTLGKLAFSDTLDLAHRK -IFHNWLMGNTTGDKRIRASVPNTWIVGDKTGTCGYAAANDIAVIWREQLSPLVIAIYTHK -LHATDKHSDQVIASVTSEIVKH- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium anyangense TaxID=1431246 RepID=UPI00138D8B75 ----LDERIGMLERRHNAVVGVYGANLDAKYTV-AHRDNDMFAMCSTFKAYLSARVLQKAQ -RGELRITDTLVVDPTAVLPNSPITGPKAGSALSLAQLCQAALQRSDNTAANMLLTVIGGP -QEITAFARSIGDERTRLDRWETELNSALPGDPRDTSTPRALGGGFRAILTGDVLDEVHRR -QLEDWMRGNTT--SSMRAGLQPGWATADKTGSGAFASTNDVGIVFGPNGERILLAVMTRT -RSADAEALRPLIAEVTTLVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sp. OCN044 TaxID=2695891 RepID=UPI00136845A6 ---SLEQSLSKIEQEIKGQVGVAVIDTQSHNQW-SYNGNQRFPMMSSFKTLACAKLLYDVE -QKKLTLNQKIDVPESGLVNWNPITENFVGSKMSLQSVCAATMLMSDNYAANLALQQIGGP -SGLTAFLREIGDQKTRLDRYEPELNYVEKGAENDTTTPIAITQTIKRLLTGDVLSTSSKT -QLQFWMTNNMFSDSLARAVLPQGWLIADRSGGGVKGSRALTAMVWKSDRKPLFIGIFIAN -SSSTLPEINQVVADISQLIFAQy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0007C850BF ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Pandoraea TaxID=93217 RepID=UPI000685CB30 ----ADSPFSDIERRHGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILSRVD -SGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP -AALTRFVRGLGDPVTRSDRYEPESNRY--RGVLDTTTPKAITTTAQHLLLGDALSASSRA -QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGTAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BF12AB ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A3BC004 ------KALADYESRTGGHIGFFAQNVVTSASL-GWRASERFVMCSTFKASLAACVLSRID -QGHDTLEATLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP -SALTAFWRALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSAPSRA -LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWPKSDTPLLVCAYTRG -GKPTETDFATAFAAIGSLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Blastomonas sp. AAP25 TaxID=1523416 RepID=A0A0N0K248_9SPHN ---AIARELAAIEARSGGRLGVALVGPDGRQLA-GHRADERFAMCSTFKLPLAAMVLENAH -KGRLSMADPLPVNDSDMVVYSPYVEAQRAKTVTVEGAASAAVSLSDNTAANLLLDRLGGP -QSFTAWLRGKRDSVTRLDRREPELNENALGDPRDTTTPAAMADTTRSLVVGNAMPVGQQR -LLYRWMENTSTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTAETGMRYTLAVYLDR -PAVKGDAASAIIADATRAVL--- ->[subseq from] GES family class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI000E093BB4 ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTLKFPLAALVFERID -PGTERGDRKLSYGPDMTVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGARNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadales bacterium TaxID=2006849 RepID=A0A3N5KIZ2_9GAMM -----AARLQSLETG-QARLGVCFVDTATGEAS-GNRMNEHFAMCSTFKLALVAACLRQAD -QGRLDLAQVLTYSEADLLPWAPVTSKNLASGMSIGALAQAAQELSDGVAANLLVKRLGGP -AAVTAMFREMGDTVTRLDRYEPDLGLVLSADLRDTTTPLAMANLVRRITTADLLQSGSRE -RLLQWMQDTNTGPNRLRAGLPADWRSGNKTGTGRTNKCNDVAITFPPGRPPIVIAAYFDS -GEQTERRHEAVLAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Leifsonia xyli TaxID=1575 RepID=A0A2W4ZSR4_9MICO -hrSVDRALADLEREYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKVFAAAQFLRSVP ---TDARDEVVHWTAADVAAYSPVTEQHVADGLTYAQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALAELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALAAVLDGSTLNSADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAG-GIRNDVARVTPPDGDPIVLSVLTTR -NDPDAAYDDALVARSAAAVLDAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RER1_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSG-PSGWLV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chungbukense TaxID=56193 RepID=A0A0M3ARR2_9SPHN ---------KEIEAETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTKADLLDYAPVVRKNAKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP -EGLTRYVRAHGDMVTRLDRTEPALNENAEGDERDTTSPAAMAGLMGRLIFRD-LKPESAE -KLRGWLNASTTGGNRIKAGLPKDWISGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKGAEAAIAETARAALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. ms191 TaxID=1827978 RepID=A0A652JUJ5_9ACTN ---ELAAELRRLESARGVRIGAFAYDPASGRTL-SYRADESFPVLSTFKAFVAAAVLDKAR -RSPGLLERKVHWTARDEVSDSPTTRGRGVAGMTVAELCHAAVTRSDNTAGNLLLREIGGP -SGLTRHHRALGDPVTRLDRWEPELNDWHPGEPRDTTTPAAAGRALERVALGTALVPEDRA -RLNGWLRATVTGSERIRAGVPEDWEVGDKTGTSSYGGAHDIAVVRPRSGAPVVLAILTRR -TTAAAPSDSVSV----------- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium czechense LL01 TaxID=1420583 RepID=A0A0J8AW20_9SPHN ---------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDATTRLDRTEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPASVN -RLRSWFNASSTGDKRIKAGLPAGWTSGSKTGSCGT-AYNDVALVKAPNGDEYVLAIYLDR -PTVDAKKAEAAIAETARAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=A0A2T3LV03_PHOAN ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDSGDSVTRLVRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium sp. B3058 49 TaxID=2183925 RepID=A0A2V5CM76_9SPHN ------DPIAEYERTTGGRIGVHALNVTTGQTL-TWRADERFIMCSSYKASLAGYVLARVD -RGEEKLDALVPYTAQDTLGWGPIAKENLAKGMTVAAMCKAAVEISDGVCANMLMARSGGP -AGLTAFLRSIGDTTTRVDHFEPALDRVPSGGPDDSTTPAAMASTLQKVVLGDVLSAHSKE -LLTRWMIGNQT-TPRLRGGLPRNWRIGNKTGHSGRDMAGDIAVAWPHPEMPIVIAVYTRG -GSPAEAQFDKAFAGIGRLVAS-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3M1WNX4_9BACT ---RLKSEIERLAELAGGRVGVGALHLETGRVV-YLHGDERFPMASTYKIPIAVQVLTRVD -REELTLDRLVTLRRRDLRPGSGLLARWLDESLSVHTLLELMLVISDNTATDVLLRLAGGP -SAVTKRLRELGIEGIRVDRPTLEIIAAFNADPRDTATPAAMVRLLQKVWRGRALSRERTE -LLFDIMRRCQTGARRIKGFLPPGTEVAHKTGTIG-GTTNDVGIITLPHGGHLALAVFVKE -STEEIAKREQAIAHIARALYDDf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=F4Y5N7_KLEOX -------------------------------------------MCSTSKVMAAAAVLKQSE -SNPEVVNKRLEIKKSDLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Mycetocola reblochoni TaxID=331618 RepID=A0A1R4JKZ6_9MICO -----EGRIDAIVDEAGVTLGVSAEDLSGAGTI-DAGSQEPVKAASVIKLPLLALLMDEAD -HGRLSLDESVTIPASNIVGGAGTLQGQFPLDITVRELMELMVQVSDNTATNVLIDRAGGF -DRINAYIEGLGYDTLWLGRKMI--HTATPPLGENWINAAEVTDLIARLYRHDILSASSSE -HIIGLMKGQLV-NTKFGAVIPRE-HLANKTGELGD-VSHDSGIILLDGHE-VALTVTSSY -AARSQTEVNRYVQRVASTVY--- ->[subseq from] Beta-lactamase n=2 Tax=Mycetocola reblochoni TaxID=331618 RepID=A0A1R4JKZ6_9MICO ------------ARAAGVDVGVAVRDLSDDRAL-FLGKLDRYTTASTIKLALAATVMTQVQ -SGELDLDDVATITEDERYGGSGVLKDRAFPQVTVGEMLDLMVTVSDNTATNKLADVVGGV -DRISDVIAAAGISAGDLHFGRKMFGPVVPSWGDVWLTPVGMDQLLTSFYRQDYLTPESAR -TIIGLMLDQQV-KTKLGASIPAE-VLAHKTGENDT-VSHDVGLLLVPGQ-ELTLSVFTTA -GEDLQATANPYVQRIGAIVYEY- ->[subseq from] Beta-lactamase n=3 Tax=Aliivibrio salmonicida TaxID=40269 RepID=B6EJY3_ALISL ---SLNDTMIDLEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLHDAD -KKIINKKTETAIAQKDLIPWSPITEKYVGKSISTEKACEATMLMSDNTAANIVLQQIGSP -SSLTAFLRLMGDSTTQLDRIEPTLNEAKKGDIRDTTTPIAMVHTINKLLLGNTLTTTDKV -TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWNEHRLPLIISIYLTQ -TDLTLAERNDIIVHVGSALFTQf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A249MXI0_9SPHN ---------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP -EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD -RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAQAAQAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium cupriresistens TaxID=1132417 RepID=A0A4Q4JPP7_9SPHN ---------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDATTRLDRTEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPTSVD -KLRSWFNASSTGDKRIKAGLPAGWTSGSKTGTCGT-AYNDVALVKAPNGDEYVLAIYLDR -PTVDAKKAEAAIAETARAALD-- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium xenophagum TaxID=121428 RepID=UPI0005B88C35 ---------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP -QGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD -RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAQAAQAALD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. NEAU-Ht49 TaxID=2483351 RepID=A0A3M2LU22_9ACTN ---DVQKELRKLETSYQGRIGAYAIDTGTGKTV-GYRAHERMPSNSTFKAILCGAVLHKAR -ADPGLMSRTFHWTKEDVVDSSPVTGENIKNGLTAAQLCEATITTSDNTAANVLLKQVGGP -AGMTRYYRSLGDPAGRLDRYETELNHWNPGEKHDTIMPACMARDLEKLTVGTALVAEDRQ -QLTTWLKATDTGDERIRAGVPQGWIVGDKTGTADYAAADDIAIAWPPSGAPVIIAIFTHR -DAKDAAFDNRVLAKTTTILM--- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio sp. 1S175 TaxID=1840087 RepID=A0A1B9PQ66_9GAMM ----VLETVETIELSSSGTIGVSVLDTETNTTW-SYKGDHRFPMMSTFKTLACAQMLYNSS -NNLLDKDALTRITKESIIPWSPITEKLIGETISTEKACEATMLMSDNTAANIVLAETGSP -KSLTLFLRLIGDDMTRLDRIEPALNEAQKGDVRDTTTPNAMTNTLNELLFGQTLNTKDKR -TLKAWMVDNKVSDPLLRSILPAKWSIADRSGAGGFGSRGITAIVWSNKRAPIIISIYLTQ -TNLDMASRNQIIVEVGNAIFKEf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. Alg239-R122 TaxID=2305989 RepID=UPI0013D99F2B -------ALRKLEQESGGRLGVACINAAGDTLF-ANRADERFAMCSTFKAPLAAALFEAHD -RGIADRFARIRVREDDFVPYAPFTENLVKEGTTLDEMAYQAVIISDNAAANIVLRAIGGP -EAFTDFLRRQGDDVTRLDRYEPELNENAIDDPRDTTSPLAMAGLLRRLLLKNEGSAAHAD -RLIKWMLDTKTGIARIRAGLPDAWRLGHKTGTAPQSCYNDVGIIFPPDQPPVLLAVYFDR -PDVAWKEAEAVIAETTRLAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. shizuoka-1 TaxID=2039281 RepID=UPI000C9CA21E ----IDQRIAALERRHNAFAGVYGQNLDSGQTV-TNRADDMFAMCSTFKAYLAARVLQKAQ -AGELRLTDTALVDPELLRANSPRTEPHVGTPMALSELCAAALQVSDNTAANVLLRVIGGP -PEITAFARSIGDERSRLDRWETELNSALPGDPRDTSTPSALGGGVRALLTGTVLDEPHRR -QLEDWMRANTT--SSMRAGLQPGWTTADKTGSGDFASTNDVGLLFGPAGERILLAIMTRT -QSDDAPGLRPLIGELTALVV--- ->[subseq from] class A beta-lactamase n=2 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=UPI000A147CEB ----------EAELRHQARIGLYALDLKTQNTI-THRNHDRFAMCSSVKTYVAARVLQKAE -RGELALTDSVTVHGADIVPNSPVTETWVGRSIPVAELCAAALQKSDNAATNYLLKTVGGP -SAITEFARSIGDNETRLDRWETELNSATPGDARDTSTPQALGDGNRALLEGTALTLESRR -QLIEWMVANST--SSLRPGMPPEWILADKTGSGGYGSTNDVGLGFGPGGQQVVLSVMMRS -ATPNADGFRPVMTEIAAVAM--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium czechense TaxID=1090573 RepID=UPI0009EBCC25 ---------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDATTRLDRTEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPASVN -RLRSWFNASSTGDKRIKAGLPAGWTSGSKTGSCGT-AYNDVALVKAPNGDEYVLAIYLDR -PTVDAKKAEAAIAETARAALD-- ->[subseq from] GES n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDD5_9BACT ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERGLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A521Q3P6_9SPHN ---------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP -EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD -RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAQAAQAALD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. SID11385 TaxID=2706031 RepID=A0A6B2UPV2_9ACTN ------AEFTALERRYAAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---RDGMGHVLRYGKKDVVANSPVTEKHVGTGMSREALCEAAIRYSDNTAANVLLADLGGP -RALGALVRATGDRVTRVERVEPLLSRWTPGETHDTTTPRQLTANLRAYVLGDVLAAPGRE -RLAGWLRANTTGNTTIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERTAEADDRLLAEAARVVVS-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia oroxyli TaxID=366584 RepID=A0A1G7G479_9PSEU -------QLAALEDRFGGRLGVFAVDTGSGTTV-THRADERFLMCSTSKMLAAAAILALRV -DRPGLLDQQVSYPRSALVTYSPETERHD--AMTVRDLCHAAMTLSDNTAMNLLLETLGGP -ERLTGFLRREGDMISRQDRPETDLN--ILDGDKDTSTPAQVAANLRSFALDDGLDPGGRD -LLVGWLKANTTGATRIKAGLPADWVVGDKTGAGGQGEINDVAVVWPPGRAPLVMAVYTAP -ADPGSNGSPETVAEAARIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans KG-16 TaxID=1441730 RepID=A0A0V9UL47_9NOCA ----VDERLREIEGRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGSLRRDETLPIGPEDIVVNSPVTSEHQGRVLSIDRLCEAALTRSDNTAGNLMLQRIGGP -GAVTAFARSVGDEITRLDRWEPELNEAARGDERDTTTAAGLARGFREVLLGSGLPAPQQR -TLLGWMRATATSDTRIRGGLPPGWTSADKTGGGNHGTVNDAGVVWSPDGQPLLLAILSDS -TTPDAPLEGAPVAETTAVLVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudodonghicola xiamenensis TaxID=337702 RepID=UPI000426CA37 ----LDQTIDRIESELGARVGVAIHDSNTGSDW-THRGDERFLMNSTVKAPLCAAILSRDD ----IDLTETLPVRAEDILEYAPVTEKRVGTEMSIADLCLAALDQSDNTATNILFDRLGGP -EQLTEFLRSIGDDVTRSDRIEPGLNIFSAGDPRDTTTPKAMIDTLRAILVGDGLSEQDQE -QLAEWMRPGGVTGDLIRPAVPNGWDVVDKSGSGNN-TRNLIAMLTPPSEDPIFVSLSISD -TEADFGTRNAALKDLGAAVMK-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A2X4YMH0_KLEOX ---AIHQKLTDLEKRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAILKQSE -SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPESWVVGDK------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. EO9 TaxID=2304063 RepID=A0A418YW10_9SPHN ---------RTIEEETGGRLGIALVDSKGALIL-GFNRDERFALCSTFKAPLAAAVLIGAE -GGKFGLDGQIPFGKDDILDYAPVVKKNKKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPTLNENAPGDPRDTTTPAAIAGLMGRLLFRDM-KGESAD -RLRAWLNASSTGDKRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKAPSGEEYILAVYLDR -PSVNAKAAEAAIAQAAQAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C02CA9 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLERLVHYTESDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=A0A2T3PP28_PHOPO ---QIAPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TQRIHLNKPVLVKQSDILGYAPITKDRVGTTMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNTAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Fischerella sp. NIES-4106 TaxID=2005456 RepID=A0A1Z4TNH3_9CYAN ---ELYNRIEEISRTAQGRVGVAATVLETGESV-ALNGDQRFPMQSVYKFPIGMAVLAQVD -QGKLKLEQRIRVEKSDFVSHSPIRDEHPQGILSLTQLLKYMVSESDGTACDVLLKLVGGP -EVVTKYLRKLGVNGVIVVSTEKEIGQDKSVQYRNWATPEAMVVLLRALDEGRGLSKSSQA -LLLRLMTETSTGLRRIKGMLPDGTVVAHKTGTSGTAATNDVGLVTLPNSQHLAIAIFVSD -STADDAAREEVIAKVARTAWDKw ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A401J1R2_SPHXE ---------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD -RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAQAAQAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI0007F443A9 -------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELINAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. ITM-2016-00318 TaxID=2099693 RepID=A0A2S8KIB0_9MYCO -----YDRIQALQRRYNTKIGVYAVDFASGRTV-SHLDGEPFAMCSTFKGYAAARVLQMVG -NGDLTLDQQVFVDPTAALPNSPRTAPNSGDRMTLGALCAAAVQVSDNCAGNLLLQTIGGP -SAITGFARSIGDDRTRLDRWEIELNSAIPGDPRDTSTPHALGDGYRTLLTGDALPPPQRQ -QLEDWMRANET--SSMLAGLPAGWTSADKTGNGDYGSTNDVGIAYGPAGQKLVLAIMTRS -QGPNAPNNRPLIGEVASVL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Shewanella oneidensis TaxID=70863 RepID=A0A2W5DKM1_SHEOE ------QTVNEFER-QGWNIGVSVIENSSNNVY-SINGDERFSTNSTVKALACAIVLSEVD -KNAVSLNDAMMINEQDVVSHSPVMKEFIGKKVTLADACKATMTYSDNTAANFAIKKSGGP -EGITSFLRSIGDDITRADRYEPDLNTNPEGDLRDTSTANTMAANFNKLLLGNILSTQSKE -QLKNWMMGNKVADNMLRLVLPTGWEIADRTGANSYGARGIISMVWSESQQPLIISIYIKK -EKTSIEEREKVISEIGRVIFTEy ->[subseq from] Class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=A0A659GIW1_CARDV -------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELINAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDTRDTSTPKEIALDLKKVAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDALIAETAKIVSDDf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium phenoxybenzoativorans TaxID=1592790 RepID=UPI0009F4E93B ---------AAIEEASGGRLGIALVDSKGAMLL-GFNREERFAMCSTFKAPLAAAVLMGAE -QNRYGMEGTLPIKQTDLLDYAPVVKANLAKGMPIADLAKAAVQVSDNSAANLLLPLVGGP -QGLTAFFRKHGDEVTRLDRTEPALNENALGDERDTTSPAAMATVMARLLFQDM-PAPAAA -QLRGWLEGSTTGGKRIRAGLPAGWKAGDKTGSCGT-AFNDVAVLRSPRGNDYVLAIYLDR -PTVPDAKADATIAEATRAVMD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Fischerella sp. PCC 9431 TaxID=1173023 RepID=UPI000478D5A6 ---ELYNRIEEISRTAQGRVGIAATVLETGESV-ALNGEQRFPMQSVYKFPIGMAVLAQVD -QGKLKLEQKIRVDKSDFVSYSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP -EVVTKYLRQLGVNGVIVANTENEIGQDKSVQYRNWATPEAMVVLLRALHEGRGLSKSSRA -LLLRLMTQTPTGLRRIKGMLPNGTVVAHKTGSSRTAATNDVGLVTLPNRQHLAIAIFVSD -STADDAAREEVIAKVARAAWDKw ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas intermedia TaxID=74315 RepID=A0A4Y9RTT6_9CAUL --------LNDLEERHGGRLGMAALDVGSQRRV-SWRGQERFAFCSTFKAFLAVATLERVQ -REEEQLDRAVAVTRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTIANIRELAFSDRLTPEHDQ -LITGWMIGSPTGANRIKAGAPQGWTVAHKTGTGSNGATNDIGMLTPLSGSPVLMAAYFTG -APATDDQRDAVIAEATRRALK-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=A0A2S7VXJ8_PHOAN ---TVNSAIEHAEKQLDARIGVSVLDGKGKQLF-GYNSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYLINADTILDYAPIFKDKVGTEVSLKEACFATMTTSDNSAANLVLNHIDGP -VGVTTFLIDSGDNVTRLDRVEPLLNEATPGDKRDTTTPYAMNKTISNLVLGSALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGHGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAVFKQf ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251YCM8_9MICO ---AADAAFTALEERFGARLGVHAVDIGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMEGAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLMLRALGGP -AELDAALTALGDDTTVVARDEPTLNEATPGDDRDRTTPRAAAALMRAYALGDALDDDERT -LFTGWLRATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDATPIVIAVHSSK -DRQDAVADDALISGAAKAAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TverLS-915 TaxID=1839763 RepID=A0A1C4LU33_9ACTN ------AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERTAEADDKLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Ant17 TaxID=1461752 RepID=A0A013WE99_9SPHN ---------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDLLDYAPVVKKNLKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFIRAHGDSVTRLDRNEPDLNENAEGDPRDTTTPAAMAGLIGRLLFSDM-QGESAE -RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR -PTVDASKAEAAIAETARAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Alishewanella aestuarii B11 TaxID=1197174 RepID=J2IG46_9ALTE ----AAQRLQALEVG-HARLGVCLLDTATGEVS-GNRMDEYFAMCSTFKLALAAAYLREAD -QGRLDLDEMLPYSEADLLPWAPVTREHLAKGMTIIALLQAAQQFSDGVAANLLVKRLGGP -AAVTAKFREMGDNITRLDRYEPDLGLVLSADLRDTTTPRAMAQLVQRITSGELLQPDSRQ -RLLQWMESTNTGSKRLRAGLPTTWRSGNKTGTGRTNKYNDIAITFPPGRSPIIIAAYFDS -GEQIEDRHQAVLAEVGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A2Z2Z6H0_9BACT ---TTKEEIQKIERQRNLTVGIALVDDGGTLLF-GHRETQRFAMCSTFKLPLAAATLKQIE -SGKWSAAERLSYSAGQLDAYAPAAKRYLPTGITVAEANQASVQLSDNTAANLLLDKLGGP -SQLTSMFRSLGDSVSRLDRREPDLNTNVSGDPRDTTTPGAMARIVAKLVYGNYLSTAGRE -QLQRLLIGNNTGDSRIRAGIASGWTTGDKTGSCPNGGRNDAAFLVSPDGRRFALTVYLNA -PSLDDKARNEVVATVARLAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. BK086 TaxID=2512165 RepID=A0A4R6I8E8_9MYCO ----LDQRIAALEKRHNAFVGLYGQNLDTKQVV-AHRDGDPFAMCSTFKAYLSARVLQKAQ -AGELALIDTVVVDPELLRPNSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDQTTRLDRWETELNSALPGDPRDTSTPRALGGGILAVLTGDVLDEPHRT -QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPSGERLLLAIMTRT -QSANTPALRDLVGEVATL----- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI000842198A ------SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLERLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. TNDT3 TaxID=2249354 RepID=UPI000E3EC7F3 ------REFERLEEEFDARLGVYAVDTGSGEEV-EHRPDERFAYASTHKALTAALVLQQNT ---PEEMEEVVTFTEEDLVDYSPVTEQHVDTGMTLMEVADAAVRYSDNTAANLLFEELGGP -DAFEDELEAIGDDVTDPERIETELNDWTPGDTSDTSTPRAMAGNLREFTLGDALPEDRRE -VLNDLLVNNTTGDALIRAGVPGDWRVGDKTGAGSHGTRNDIAVIWP-------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D17395F ---QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Plantibacter cousiniae TaxID=199709 RepID=A0A1T5I9I1_9MICO ---DLSGEFQALEAEFGARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR ---GSARDEVVTWSAEDVEAYSPVTSEHVETGLTLSQLAEAAVRQSDNTALNLVLARIGGP -AALDAALVTLGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFTDNLTRLVDGSYLESADRA -TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GMRNDIAIIDRPGGDPIVLTILTNT -LDPDAEYDDALVAEAARVALAAf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudonocardia oroxyli TaxID=366584 RepID=UPI000B80E9F3 -------QLAALEDRFGGRLGVFAVDTGSGTTV-THRADERFLMCSTSKMLAAAAILALRV -DRPGLLDQQVSYPRSALVTYSPETERHD--AMTVRDLCHAAMTLSDNTAMNLLLETLGGP -ERLTGFLRREGDMISRQDRPETDLN--ILDGDKDTSTPAQVAANLRSFALDDGLDPGGRD -LLVGWLKANTTGATRIKAGLPADWVVGDKTGAGGQGEINDVAVVWPPGRAPLVMAVYTAP -ADPGSNGSPETVAEAARIAA--- ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112969 ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQSTYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium barthaii TaxID=1054037 RepID=A0A4R6FDC6_9SPHN ---------KEIESATGGRLGVALVDSKGALML-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQISFTKADLLDYAPVVKANLKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHGDMVTRLDRNEPSLNQNVEGDERDTTAPAAMAGLMGRLIFRDL-APASAE -KLRGWLYASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI0007F8A36C ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium KEBCLARHB70R TaxID=2582866 RepID=A0A5R9JFJ0_9PROT -------AVALYERDSGGHVGVFAQNLRTGATL-AWRAGDRFVMCSTFKASLAACVLMQVD -RGLDSLASRIRYGAADIGDHAPVARANLASGLPVGEACEAAVEQSDNTCANLLLSRIGGP -PVLTSFWRRIGDDVSRLDDPEPILNFRAPGDAHDTTTPSAMADTLRRLVLGNVLSEGSRQ -ILIRWLLGCRTGGRRLRAGLPSSWRIGNKTGNNGGDAAGDIAVAWSARNAPIVMAVYTRG -GSPSAAQTDAVFAGIGRHI---- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. 852002-51057_SCH5723018 TaxID=1834094 RepID=A0A1A2GAK9_9MYCO ------DRLGELEGRYDAYVGLFATDLGSGRTL-AHRDGDPFAVCSTFKAYSAARVLQLAQ -RGELDLRQAVFIDPGALLPNSPVTAPQAGRTMPLAQLCAAALQRSDNAAANLLLRAIGGP -PAVTDFARSLGDEHTRLDRWETDLNTAIPGDPRDTSTPRALGGGIQSLLTGTVLGEPQRR -QLEDWMRGNVT--STMRASLPPGWTSADKTGTGDYGSTNDIGIAYGPGSQRVLLSVMTRS -ASKDADALGPLIAEVT------- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0009B998E4 ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQRFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDGGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLDNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] Uncharacterized protein n=1 Tax=Rhizobium sp. AAP43 TaxID=1523420 RepID=A0A0N0JAY1_9RHIZ ---DIAQTAEQIEARLNLRIGLAVIDTGGGPGT-FRKADERFAMASTFKALACAAALDGGD ----AVLDRQSAVAQEDLQAYSPVTDKLVGARRTTRDFCAMMLRTSDNTAANKVLEAIGGP -TALTAFLRANGDEVTRLDRFEPDLNQATPGDPRDTTTPRAMAETMEKLVLGDALAVPAAR -QLEAWMAANSVAGGMLRASLPKDWAIADRGGAGGHGTRGIVAVIRPPARAPLVVAIYLDG -TQHPLKVRDAAMAELGAAIVAAy ->[subseq from] Beta-lactamase n=2 Tax=Pandoraea pnomenusa TaxID=93220 RepID=A0A378YLE1_9BURK ----ADSPFSDIERRHGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILSRVD -SGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP -AALTRFVRGLGDPVTRSDRYEPESNRY--RGVLDTTTPKAIITTAQHLLLGDALSASSRA -QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGTAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BCABAC ------SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLERLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTHFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIATTAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia guartelaensis TaxID=2546446 RepID=A0A4R5LBA3_9BURK ---AAESPIAEVERRYGGRLGVFAVDTGSERTL-SHRADERFLMCSTFKGLLAAQTLARVD -SGEERLDRLVPYTEKDLIFTSPVTKANLAKGLPVETLCQAILEQSDNTAAVLLMRSAGGP -AGLTQFVRGLGDTVTRSDRYEPDSNHY--NGALDTTTPRAIATVARSLLLGDVLSPRSRA -QLERGMTACKPGLNRIRAALPEGWQAADRPGTSLTGETNDYALVRPPGRAPLLVAAYYDA -PGVSMQTRETVLREAGAAFVQ-- ->[subseq from] Beta-lactamase n=2 Tax=Listeria weihenstephanensis TaxID=1006155 RepID=W7CD33_9LIST ---QVKTALEKLEKKYGATLGIYGMD-GTGKQIiGFNEQERFAYTSTFKAIAGGILLKNLT ---DEQLNKRITFSKEDLVDYSPITEKHVASGMTMKEIINAAMDYSDNTAGNLMLHQLGGP -TGFEKELVKIGDKTMKPVRYETELNTAVPGDIRDTTTPEAMAKSLAYLVTEGNLPADRLA -YFKQTLINNTTGGKLIRAGVPDGYVVGDKTGAGSYGTRNDIAVIYPKDKKPLVWVIYSKK -TGKDDEYNDQLIADAAKVLSDYy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X166_9BACT ---EFAKNIEAIAKEARGVVGVGIMDLKSRETV-VLNPSHKFPMQSVFKFPLAMAVLDQVD -KGKFTLAQKIHVTKQDVSPWSPLSKKYPNGELTLAELLGYTVSMSDNNACDILFKLLGGP -KNVEDYIRTLGVKDIAIVATEEEMSKHWDVQFTNWCRPAAMLQLLDVIYKGKKLSQTSND -FLLKVMTETTTGPNRIRGLLPKDAKVAHKTGTSNTAASNDVGIMTLPNGKQVAVVVFVSN -AAADEKTRDAVIAKITKAAWDYy ->[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudonocardia TaxID=2619320 RepID=A0A1Q8LKR3_9PSEU --------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVTKALMAGFTLHRSL -SDPGLLARPVRYGRADLLEYAPVTTRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRALVLGDALPAPQRD -RLAGWLRANTTGDRQIRAAVPAGWVVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTVP -ADADKPRGEAAVAAAARAAVA-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000C7000AB ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. 9120 TaxID=1500897 RepID=UPI0009DD07DD -----ESPIAGIERRYGGRLGLFAVDTGSGRTL-AYRADERFLMCSTFKGLLVAQVLARVD -AGKETLERLVHYTERDLIFTSPITKANVAQGMSVGALCQAAVEVSDNTAAILLMRSTGGP -AALTRFMRGLGDSVTRSDRYEPESNQY--SGLLDTTTPRAIATSAARILLGDVLSHQARR -QLEEWMVACKPGLNRLRAALPANWLAGDRPGTSVERETNDYAIVRPPGRAPLLVAAYYDA -PGVSMELRETVLREAGH------ ->[subseq from] class A beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=UPI000A3702F9 ---AADAAFTALEERFGARLGVHAVDIGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMEGAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLMLRALGGP -AELDAALTALGDDTTVVARDEPTLNEATPGDDRDRTTPRAAAALMRAYALGDALDDDERT -LFTGWLRATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDATPIVIAVHSSK -DRQDAVADDALISGAAKAAAE-- ->[subseq from] Class A beta-lactamase n=2 Tax=Ideonella sp. KYPY4 TaxID=1862385 RepID=A0A437RLI8_9BURK ---ALQNELAALEARSGGRLGVAVLDTASGASA-GHRADSRFGLCSSFKLLLAAATIERVE -AGAWPSTRRIAYTAADLIPPSPVLRERLAEGLTALQMAQATQETSDNAAANLLLRELGGP -AGLTAWLRRQGDAVTRIDRWEPEMNVVAPGDERDTSTPAAIAATGARILTGPVLSPAGRE -QLIGWMVATQTGARRLRAGLPAGWKAGDKTGTGMPDRYNDVAIIWPGQRAPWLLAAYFES -RHRDRPEDEAVLAEVGRLV---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BDF360 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIHAVLPAGWQAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077P7W3_XENBV ----LKDKIKNLEAQ-GWQVGVSILDYNGNKIE-SVNGDKRFPLDSTVKALACANVLAKVD -NKSLRLEDSVLINEKDIVTYSPITEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP -SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE -QLKEWMIGNKVADNMLRAELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYVRK -SNTSLEERSEKIAEIGMVIFSKy ->[subseq from] Beta-lactamase n=2 Tax=Bordetella genomosp. 8 TaxID=1416806 RepID=A0A1W6YMZ7_9BORD -----GSALADIERRNGGRLGVFAVDTATGRTL-AHRADERFLMCSTFKGLLAAQVLQRVD -GGAERLDRLVRYTEKDLIFTSPVTKANVGRGMSIEELCRAVLVESDNTAAILLMRSAGGP -AGLTRFVRGLGDTVTRSDRYEPDSNRA--DGAFDTTSPKAIATVAQGLLLGDVLSTNSRA -TLERGMADCKPGLNRIRAALPADWQAADRPGTNIDNETNDYALVRPPGRTPLLVAVYYDA -PGVKMDRREAVLREAGKAFVQ-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00066D373A ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio logei TaxID=688 RepID=UPI0003C7BAEA ---SLNDTIIDLEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLYDAD -KKIINKKTETAIAQKDLIPWSPITEKYIGKSISTEKACEATMLMSDNTAANIVLQQIGSP -RSLTAFLRLMGDSTTQLDRIEPTLNEAKKGDIRDTTTPIAMVNTINKLLLGNTLTTTDKV -TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWNEHRLPLIISIYLTQ -TDLTLAERNDIIVHVGSALFSHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Gloeocapsopsis sp. AAB1 = 1H9 TaxID=1433147 RepID=UPI000CF709C7 --nELQDQIEQISHAAQGRVGVTATVLETGESV-ALNGDQRFPMQSVYKFPIGMAVLAQVD -QGKLKLDQRVRVEISDFVSHSPIRDENPQGVLNLAELLKYMVSESDGTACDVLLKLVGGP -EAVTQYLRDLGVDGIVVANTEKEIGQDKTVQYRNYATPDATAVLLRALYEGRGLSESSQA -LLLRLMTETPTGLKRIKGLLPDGTAVAHKTGTSRTAATNDVGIVSLPNKQHLAIAVFVSD -STADDAIREEVIAKVARAAWDEw ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. Z007 TaxID=627495 RepID=UPI000B498257 ---------AEIEKEVGGRLGVALVD-RSGALLlGFNRDERFAMCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -EGLTSFMRAHGDTVTRLDRNEPTLNENAEGDPRDTTTPAAMAGLMGRLFFRDM-KPESVD -KLRSWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVKAPNGDEYILAIYLDR -PSVDAKKAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sandarakinorhabdus sp. AAP62 TaxID=1248916 RepID=UPI0009DA0869 ---ALRRAISQIERSAGGPIGISLIDTQTGERF-GHRANDRFPLCSTFKLLLAARLLHGAD -KGEWTMNDRLPVTKADLLFNAPFTERRVGGSASLLELAEAMAVLSDNPAANIALARIGGP -VALTRWLRATGDRITRLDRNEPEMNNERPGDPRDTTTPTAMLATTRALVEGGILSSAARR -TLFGWMQASKTADSMIRAALPPGWQEANKTGAGSWHARNIVSVITPPGRKPIWVAAYLFA -AKSELGERNRQFVPLGRAIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JGB5_ECOLX --------------------------------------------------MAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVL----------- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. B7740 TaxID=1564114 RepID=A0A0D5AGE5_9NOCA ---SAEQAYLELEARDTARLGVSVLDLETGSTQ-SYRGGERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTITAEDKVPESAVD-WDPGSVVTIADLAVAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPGDPRDTTTPDSLAAGYRTLLDGDVLAAASRK -QLLEWMGDTETSAARFRAGIAPQWTSADKTGTGSYGVSNDAGLLLGPDGQRILLVVLSAT -TSDDSPAMNPLVADATRAAVQQ- ->[subseq from] Class A beta-lactamase n=1 Tax=Acinetobacter seifertii TaxID=1530123 RepID=A0A5E9PDR6_9GAMM ------------------------------------------------------------- --------KRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium estronivorans TaxID=1577690 RepID=UPI0012399967 ---------KEIEAGTGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGQVSFTKADILDYAPVVKKNAKRGMSMEELAAAAVEASDNSAANLLLPMVGGP -EGLTRYIRAHGDMVTRLDRTEPTLNENAQGDERDTTSPAAMAGLMARLIFTD-LKPASAD -KLRGWLNASTTGGNRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYVLAIYLDR -PTVDSKAAEAAIAETAGAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A511FIM8_9PROT --------ISQYENETGGHVGFYAENTKTGATL-GWRTDERFVMCSTFKASLAACVLARVD -GGLDTLERPLSYTAADIGDYAPVAKANLAKGMTIRELCAGAVEQSDNTCANLLLTHIGGP -SVLTAFWRHLGDKTTRLDDVEPYLNRTPPGAIQNTTTPRSMAFILQHLVSGPVLSAPSRT -ILTDWLIRCRTGEHRLHAGFPSAWKIGDKTGNNGKDAAGDIAVIWPHPETSIVVCAYTRG -GHPTEQQLSSVFAGIGKLVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A354EQH9_9CAUL --------LADLEARHGGRLGVAALDVGSQRRV-SWRGQERFPFCSTFKAFLAVAILERVQ -RDEEQLDRAVPIVRTDMIPHAPVTEKAIGRTLTIRELIQAAVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTLISRLEPDLNTALPDDPRDTCLPDQSIANIRELAFGDRLIPTHDQ -MIQGWMTASPTGPNRIKAGAPQGWTVAHKTGTGANGTANDIGVAFPLSGAPVILATYFTG -ATASDDQRDAVIAEATRRAFK-- ->[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI00128D3967 -------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGMPLKELISAAIQYSDNTAGNFLFTQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] Class A beta-lactamase n=1 Tax=Schumannella sp. 10F1D-1 TaxID=2590779 RepID=A0A506Y4Y4_9MICO -----ALDLAALEQRYDARLGVIATDTATGRTV-TWNADARFAHASTLKALAAGLVLKRE- --GVAALDDPVAIPAAPLIDYSPVTEQHAGGTMTLGDVAAAAVELSDNTAGNLLFERLGGV -DALQRELRKLGDRTTRVDRPEPELNTATPGDSRDTSTPRALVSDLRSLAVGAALAKPERT -ALLGWLDGSQTGSTLIRAGLPTGWTAGDKSGAAGYGTRNDLAVVHPPNGAPIVIAVLSSR -DAADADYDDALIAAAASAAL--- ->[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. Leaf44 TaxID=1736220 RepID=A0A0Q4M2N6_9MICO ---EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD ---DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -AGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFTATLARITDGDWLAADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAARYDDALVAEAARIAL--- ->[subseq from] GES n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDJ8_9BACT ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSPL -ASERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. CCH11-B1 TaxID=1768781 RepID=UPI00082D9B60 ---------KEIEAETGGRLGVALVDANGALIL-GFNRDERFAMCSTFKAPLAAAVLIGAE -GGKFGLEGTIPFGKDDLLDYAPVVKKNLKRGMTMGELAQAAVEVSDNSAANLLLPMLGGP -DGLTAFMRAHGDTVSRLDRDEPALNENVEGDPRDTTSPAAMAGLMGRLIFRDM-AAESAA -KLRAWLNASSTGDKRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKSPSGDEYILAIYLDR -PTVNAAKAEAAIAETAQAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00081DFBCC ------AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERTAEADDKLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. MI1205 TaxID=407020 RepID=A0A126R663_9SPHN ---------RTIEEETGGRLGIALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAVLMGAD -AGRFGLEGQVAFTDKDLLDYAPVVKANRKRGLSMEELAKAAVEVSDNSAANLLLPMIGGP -EGLTAFVRAHGDTVTRLDRVEPALNENAQGDPRDTTSPAAMAGLIGRLLFRDM-QAESAT -RLTSWLNASKTGDKRIKAGLPPGWTSGGKTGSCGT-AFNDVALVEAPSGERYILAIYLDR -PTVDAKAADAAIAEAARAALD-- ->[subseq from] Beta-lactamase n=3 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A1L5BLN4_SPHIB ---------KEIETESGGRLGVALVDGKGALIL-GFNRDERFAMCSTFKAPLAAAVLAGAE -GGKFGLEGQISFAKADLLDYAPVVRKNVKRGMSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTRFIRAHDDMVTRLDRNEPSLNENAEGDERDTTSPAAMAGLMGRLIFRDL-APESAG -KLRGWLNASTTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A3R7EAR7_9BURK -------SLADVERRNGGRLGVFAIDTGSGRTL-THRADERFLMCSTFKGLLAAQVLARVD -AGKEHPDRLVRYTEKDMIFTSPVTKAHLAEGMPVGALCQAIVEVSDNTAAVLLMRSAGGP -AGLTQFMRGLGDTVTRSDRYEPASNRY--SGVLDTTTPRSITKSVSQILLGNVLSPQSRA -QLEKWMIASTPGLNRLRAALPPDWIAGDRPGTSVEEQTNDYAIVRPPGRAPLLVAAYYDA -PALGMPAREAVLREAGAVFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D17705F ---QIEPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAINSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMTELNTTIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CLI2509 TaxID=1984801 RepID=A0A249LRK8_9ACTN ------AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERAAEADDQLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RJE3_9BACT ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium GWE1_67_11 TaxID=1797583 RepID=A0A1F8IBA7_9PROT --------LNDLEARHGGRLGVAALDVASGRRV-LWRGQERFAFCSTFKAFLAAATLERVQ -RDEESLDRAVAVPRADIVPHAPVTEKAVGRTLTIRELMQATVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSERLTPENDA -LLHGWLTASPTGPNRIKAAAPEGWTVAHKTGTGANGTANDIAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=UPI000D175BAA ---QIAPELTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGS -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYGHALSETART -QLKQWMMDNKVSDPLLRAALPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=2 Tax=Bordetella genomosp. 9 TaxID=1416803 RepID=A0A261R4J4_9BORD -----GSALADIERRNGGRLGVFAIDTATGRTL-AHRADERFLMCSTFKGLLAAQVLQRVD -SGAERLDRLVRYTEKDLIFTSPATKANVGRGMSIEELCRAVLVESDNTAAILLMRGAGGP -AGLTRFVRGLGDTVTRSDRYEPDSNRA--GGVFDTTSPKAIATVAQRLLLGDVLSTSSRA -MLERGMADCKPGLNRIRAALPADWQAADRPGTNIDNETNDYALVRPPGRAPLLVAVYYDA -PGVRMDRREAVLREAGTAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI000A021638 ---DLDKTLQELEKSYNGRIGAVGIDLGTGKTV-GYRADERFPFNSMFKVFACAAVLHKAR -TAPGLMDKVVRWKPADMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP -GGLTEFFRATGDRTSRLDRPEPTLTQWKPGEERDTSTPAAAAQTFTKLTTGKTLHPRDRE -RLVGWLRANLTGDNRIRAGLPKDWTIGDKTGTGGYGTANDLAIVWAPGSAPIILSVFTNR -NVNNTPNDDTVIASTATALAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C1A69F ------SPLAEIERSNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLERLVHYTESDLIFTSPVTKANVDQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Class A beta-lactamase GES-42 n=12 Tax=Bacteria TaxID=2 RepID=A0A4Y5ULY1_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Roseomonas sp. TAS13 TaxID=1926319 RepID=A0A1Q2YN62_9PROT ---------IEYETSTGGHVGLHAENLRTGWKL-TSRSDERFVMCSTVKASIAACILSQVD -RGTIRLDDPIRFGANDVEGYAPVATENLGRGLSIREMCKAAVEESDNVCANFLLTRLGGP -AAMTAYWRSLGDRVSRLDDPEPILNRTPPGDVRNTTTPAAMAATLRRMVLGSALSPASRT -DLRTWMIGCKTGAHRLRAGIPSSWRIADKTGNNGKDGAGDIGVVWPKPDVPIVIVAYTRG -GTPTEQHFQKLFAGIGQEM---- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. DHOM06 TaxID=2291023 RepID=A0A3D8K287_9BURK ---AAESPLADIERRHGGRLGVFAVDTGSGRTL-SHRADERFLMCSTFKGILAAQILARTD -SGQERLDRLVHYTKNDLIFTSPVTKANLSRGMSVEALCQAILEESDNTAAILLMRSAGGP -AALTRFIRGLGDTVTRSDRYEPDSNRY--SGVLDTTSPRAIVTVARSLLLGDVLSPKSRT -RLERGMIACRPGLNRIRAVLPAGWQAGDRPGTSVESETNDYALVRPPGRAPLLVAVYCDA -PGVSMDDREAVLREAGKVFVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=A0A5F0MIU8_CARDV -------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFAFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYADIGMPLKELISAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKLAIEHKLPTDKLE -FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDELIAETAKIVSDDf ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. GZWMJZ-114 TaxID=2494734 RepID=UPI001011C986 ------AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERAAEADDKLLAEATQVVVR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rhodococcus sp. BUPNP1 TaxID=1432786 RepID=A0A225TMQ9_9NOCA ----VDERLKEIEDRYAVRLGVVAQSPVTGRVH-TYRADERFAICSPFKVYAAAAILRLEA -EGTLRLDETLPIDPDDIVVNSPVTSEHQGRVLPLDRLCEAALTRSDNTAGNLMLQRIGGP -EAVTAFARSVGDGATRLDRWEPELNEAARGDQRDTTTAAGLSRGFGEVLLGSGLPAPQQR -TLLGWMRATTTSDTRIRGGLPSGWTSADKTGGGNHGTVNDAGVAWSPDGQPLLLVILSDS -TTGDP------------------ ->[subseq from] Beta-lactamase n=1 Tax=Hapalosiphonaceae cyanobacterium JJU2 TaxID=2109628 RepID=A0A328I8Y3_9CYAN ---ELYNRIEEISRTAQGRVGVAVTMLETGESV-TLNGDQRFPMQSVYKFPIGMAVLAQVD -QGKLKLDQRIRVEKSDFVSHSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP -EVVMKYLRDLGINGINVVNTEKEIGQDKSVQYRNWATPEAMIVLLRALHEGRGLSKSSQG -LLLRLMTETPTGLRRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLPNRQHLAIAIFVSD -STAEDAAREEVIAKVARAAWDKw ->[subseq from] Putative beta-lactamase class A n=2 Tax=Novosphingobium TaxID=165696 RepID=U2Y7P4_9SPHN ---DLHERLGAIERAAGGTLGAYVLDTASGEGT-GWRQDERFAQCSSFKLSLAALALHLQE -AGEITLNERIAFTKADLLQHSPVTSQNLDTGMTIGELAQATMVTSDNAAANLLLHRFGGP -ERLTAFWRALGDDTSRLDRYEPELNDVPPGEIRDTTTPVAAAHTLARLLTDNALREPSRD -TLIRWMIAVETGGKRLRAGLPAGWRAGDKTGTGINATYVDIGWFELPSGQMVVVTSYFRP -GKTIDPGAEFALAEVGRVAAD-- ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium sp. CECT 9192 TaxID=2006083 RepID=A0A1Y6MI31_9GAMM ---QISPELAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TQRIDLNQAITIKQSDILSYAPVTTNRVGKSMTLAQLCNATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDKITRLDRIEPNVNNVSAAELRDTTTPIAINSTLYHLLYTDALSTSARA -QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMAELNTTIANIGQLIFQH- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A132DJG6_BURVI ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. SA3_actF TaxID=682181 RepID=UPI0006822E19 ------AEFTALERRYRAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERGEPLLSRWTPGETHDTTTPRRLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERTAEADDKLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Tu6071 TaxID=355249 RepID=F3ZKP4_9ACTN ------AEFTALERRYGAHLGVHAVDLGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERAAEADDQLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Biostraticola tofi TaxID=466109 RepID=A0A4R3YZF8_9ENTR ----LQALLKQQEMRLHARIGMSIVDAQGQPVF-GYRQHDRFPLTSTFKVLACAALLDSLH -QKAGSLEEKLTLQPGALLDYSPVTRDYLPPAISLGTLCKAAVSYSDNTAANRILTYLGGP -DAVTRFMRANGDQLTRLDRTEPTLNEARPGDVRDTTTPESMTVALHTLLATSLLTPPHRE -TLHGWMRDDKVADALLRAALPSGWDIADKTGAGGNGSRAIIAAVTPPEEPPFYLAIYITQ -TGASMKQADSAIASIGRHLF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. HN-Y73 TaxID=2320269 RepID=A0A420EC05_9SPHN ------DQLAALQSSTGGMLGAYILDTQSQKGF-GINEAQRFPHCSSFKLSLAALILQQAD -KGNLDLDERIHYTEADLMFVSPVTTRNLEKGMTLEELAKATQTTSDNAAANILLHRLGGP -EVLTGFWRSIGDSVSRLDKTEPALNKVEPGAVHDTTTPQAMAHTLSRLLTGDVLSDNSRA -KLWTWMQETRTGLDRIRAGLPQDWSAGDKTGTFFQDTYVDIAFVRPPDSAPLAITAYYRT -SDKMEPETLAILAKIGEIAH--- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q3SAW3_PSEAI ---DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID -AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP -PLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG -QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA -PELQGEERALLIASVAKLAR--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. DfronAA-171 TaxID=1839777 RepID=A0A1C4TA24_9ACTN ------AEFTALERRYRAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERGEPLLSRWTPGETHDTTTPRRLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERTAEADDKLLAEATQVVVR-- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas sp. ODNR1LW TaxID=2683260 RepID=UPI001412C290 --------LSDLETAYGGRLGLAALDVGSGRRV-LWRAQERFPFCSTFKAFLAAATLERVQ -RDEEQLDRRVRITEADLIPHAPVTGPAVGRSLTIRELMQAAVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSDRLTPEHDA -LLHGWLTASPTGPNRIRAGVPEGWTVAHKTGTGANGATNDVGMLTPLSGSPVIIAAYFVG -ATATDDQRDTVIAEATRRALK-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001068511B ---SHAQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVGYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5FT67_9ACTN ---NVKKQLRKLEASYQGRIGAFAIDTGTGRTI-SYRGGELFPSRSTFKAILCGAILAKAR -TEPGLLDRTLPWTAADVVSASPITGENIKNGMTVERLCHAAITISDNTAANLLLRQIGGP -AGPTRYCRSLGDRIGRLDRWEPELNDWKPGEKRDTVAPGSMARNLQKIAVGSTLVPKDRQ -RLNGWLRASTTGTERIRAGLPQDWIVGDKTGDAAYAPGSDIAVAWPPSGAPLIIAVYANR -NDPAATMDNSVIAKTATLLA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Curtobacterium sp. MCPF17_002 TaxID=2175645 RepID=A0A2W1WFA7_9MICO -----EPALAALESEYGATIGVVATDTVTGASV-SHNRDRRFGYASSIKAFAAAEFLRSVH ---GADRDERVRWTAADVAAHSPVTEQHVADGLSYDELAEAAVRQSDNTALNLVLTRIGGP -SGLDAALADLGDDVTRVLHDEPELNTIEPGSTEDTTTPAAFAADLATVLDGDTLSGADTD -QLVAWMSGNATGDTLIRAGAPEGWTVADKSGGAG-GIRNDVALVTPPGGHPIAVAVLTTK -NDPGAVYDDTLVAKTAAVVLDAf ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium angustum TaxID=661 RepID=UPI0005EB561C ----VNSAIEHAEKQLGARIGVSVFDGKGKQLF-GYHSDQLFPLMSTFKTLACAKLLHDNQ -INNGMMDKTYQITADSILDYAPVFKDKVGTEVSLKEACFATMTTSDNSAANLVLSHIGGP -VGVTTFLIDGGDSVTRLDRIEPLLNEATPGDKRDTTTPYAMNKTITNLVLGNALNESSKQ -QLKDWMEANKVSNGLLRSVLPKGWEIADRSGAGGNGSRGITAVVWNEQKQPLVISIYLTG -TKASIPERDEEIAQIGQAILQQf ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI0009C0CB31 ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSDQRFPLMSTFKTLACAKLLHDNQ -ITQGMMDKTYPVTANAILDYAPVFKDKIGTEVSLKDACFSTMTTSDNSAANFVLAHIGGA -EGVTKFLIDNGDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI001324AE35 ---EVTKQLRALEASYRGRIGAYAIDTATGRTF-GHRSHERFPSNSTFKAILCGAVLNKAR -ADPGLMERTLHWTREEVVKNSPVAEENIKNGLTTARLCHAAITLSDNTAANVLLKQIGGP -AGMTRYYRSLGDPVGRLDRFEPELNEWQPGEKRDTIRPAFMAHSLAELTVGNALVPADRR -QLIDWMKASSTGGARIRAGLP-GWTVGDKTGTGGYANASDIAIAWPPSGAPVIITVYTNR -DGDHPEIDDGVIARTATLLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=M1IEX6_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAPVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVG--------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. MWU12-2534b TaxID=2071715 RepID=A0A365VRQ1_9PSED -----------------------------------------------FKVMLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTIPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMD----------------- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingomonas sp. CDS-1 TaxID=2004404 RepID=UPI000B3C3196 ---------KEIETETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAILTGAE -GGKFGLEGQISFTKADILDYAPVVKKNGKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP -EGLTMFIRAHGDTVTRLDRTEPTLNENVEGDERDTTSPAAMAGLMGRLIFRD-LKTESAG -KLRGWLNASTTGANRIKAGLPKDWTAGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDAKAAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Fischerella muscicola TaxID=92938 RepID=UPI00030DAD1E --nELYNQIEQISRTAQGRVGVAVTVLETGESV-TLNGDQRFPMQSVYKFPIGMAVLAQVN -QGKLKLEQRIRVEKSDFVSHSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP -EVVMKYLRELGINGIIVANTEKEIGQDKSVQYRNWATPEAMIILLRALHEGRGLSKSSQT -LLLRLMTETPTGLRRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLPNGQHLAIAIFVSD -STADDTAREEVIAKVARAVWDKw ->[subseq from] BEL family class A extended-spectrum beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI0008FBAF28 ---DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID -AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP -PLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG -QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKEYVLSVYTNA -PELQGEERALLIASVAKLAR--- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacteraceae bacterium OTSz_A_272 TaxID=1759059 RepID=A0A1B1AIV3_9CAUL -------RFATIERRIGGRVGVAALNTATGDWI-GRRIQERFAMCSTFKWLLAAHMLHFDS -HLPDYRDQRMRYTEADLLDYAPVTRANIVNGMSILELCRAAVVVSDNTAANLLLRIADGP -PGLTNFIRSTGDGITRLDRIEPELNVVPLGEERDTTTPDAMVRTLQRILLETILSGSHRE -RIIGWMVESPTGRERLRAGIPSSWRVGDKTGTWHNNATNDVAIAWPPNGAPIVIASYLHG -STVEPAQRNAAHAEIARIIVEQf ->[subseq from] class A beta-lactamase n=1 Tax=Roseibium denhamense TaxID=76305 RepID=UPI0012BCF27B ---ALENKLIALEKRENAKIGVALLDAETGHRF-SYRGSDRFALNSTFKAFACSALLARSE -TGQILMEDTRSIREQDLVPWSPVTENRTGTDITLFEACEATMVYSDNTAANVVLDALGGP -AALTAFMRSAGDTETRLDRIEPEMNVVPDGSLQDTTTPEAAAASLQTFVMGDVLNAKSKA -QLVEWLTANTTAKNMLRKHLPAGWSIGDRSGASRDRKRSVIAVIYPPNRLPLFAAVYLQL -QQAKISKRDAIIAEFAETLFD-- ->[subseq from] Beta-lactamase n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=A0A0M0SJS6_9CYAN ---ELYNRIEEISRTAQGRVGIAATVLETGESV-ALNGEQRFPMQSVYKFPIGMAVLAQVD -QGKLKLEQKIRVDKSDFVSYSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP -EVVTKYLRELGVNGVIVANTENEIGQDKSVQYRNWATPEAMVVLLRALHEGRGLSKSSQA -LLLRLMTQTPTGLRRIKGMLPNGTVVAHKTGSSRTAATNDVGLVTLPNRQHLAIAIFVSD -STADDAAREEVIAKVARAAWDKw ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C165FA ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IZE2_9ZZZZ ------------------------------------------------------------D -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter geojensis TaxID=1342299 RepID=A0A196Q3U4_9RHOB ----LGVEIRALEKRHDARIGVMVRHPASGWYW-GYRENERFLMNSTFKSVLCAAILYQVD -RQVLDLNTKIKISGQDILHYAPVTKKNIGSALPISDLCFATLDQSDNTAANLLINLLGGP -KGVMTYLDRINDAVTRLDRIEPSLNDFVAGDPRDTTSPAAMTATWQKMLTGDALRPTSRA -QLAEWMRHGSVTQEFLRKSAPIGWQIIDKSGDGRKHTRSIVAMMTPLAAAPYFVAIYVSD -TPASWVERNAIVAEIGRAIID-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=UPI0006AA1E5C ---ELYNRIEEISRTAQGRVGIAATVLETGESV-ALNGEQRFPMQSVYKFPIGMAVLAQVD -QGKLKLEQKIRVDKSDFVSYSPIRDDNPQGVLSLAQLLKYMVSESDGTACDVLLKLVGGP -EVVTKYLRELGVNGVIVANTENEIGQDKSVQYRNWATPEAMVVLLRALHEGRGLSKSSQA -LLLRLMTQTPTGLRRIKGMLPNGTVVAHKTGSSRTAATNDVGLVTLPNRQHLAIAIFVSD -STADDAAREEVIAKVARAAWDKw ->[subseq from] Beta-lactamase Toho-1 n=1 Tax=Brevundimonas sp. SH203 TaxID=345167 RepID=A0A1V1UY48_9CAUL --------LTDLEARHGGRLGVAAFDVGSHHRV-SWRGQERFAFCSTFKAFLAVAVVERVQ -RDEERLDRAVPVVRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI -AVWREWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTLANIRELAFGDRLTPPHDQ -MLQGWLMASPTGPGRIKAGAPQGWTVAHKTGTGANGTANDIGVAFPTSGSPVVLATYFTG -ATASDDQRDAVIAEATRRVFK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520EIF7_RHOSO -----EQPYSQLEARDAARLGVSALDLTSGSIQ-SYRGDERFAFCSTFKVYAVGAVLAAVD -AGRLQLTDTRTIAAEDKVPESAVD-WAPGSVVTIADLASAALTKSDNTSGNLLIREAGGT -AALTDFARSLGDTEFRLDRIEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDALTQASRE -QLLDWMAGTQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TS--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Xanthomonadaceae bacterium CU05-9 TaxID=2571175 RepID=UPI00117EEBC4 ---SFTAQVSDLTKSVDADVGIALVS-NDGKLLrEFNSGKRFAMCSTFKLPLAAMALQDAR -QGKYRLDHPLKFKKSDLDAYAPVATRYLPSGMTVLEAVHASVQLSDNTAANLLLRQAGGP -KVLTQAFRRWGDNVSRLDRNEPTLNTNLPGDPRDTSTPVAMAKLTARLVYGTLLDKQDRL -SLERLLIGNQTGDNTIRAGVPSSWIVGDKTGSCERGGRNDLAFLRSPAGKKYVLAVYVNA -PKIEAPKRDQLVAEITKLAL--- ->[subseq from] Beta-lactamase n=2 Tax=Celeribacter ethanolicus TaxID=1758178 RepID=A0A291GFV0_9RHOB ---------QDRERELTARIGVCVRNLATGQVY-LHRAEERFAMCSTFKASLAALCLRESD -EGALDLGEALAFGAEDLLPTSPVTKAYVQAGLEIRSLCQAVVEWSDNTAANLLLARVGGP -ASVTRFFRDMGDPVSRLDRVEMDLNSNSPGDARDTTTPLAMAQNVQRMTMEGVLSERSRS -LLVDWMRNEQNAKNRIRAAVPRSWEVANKPGTTPNGAANDIAMLWAPEGRAFAMAIYVDT -KKGNTPAAVSAIRGIAEVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. MEB024 TaxID=1589899 RepID=UPI0005BA12D8 ---EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDSTD ---DAELDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -TGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFIATLARITDGDWLAADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGHPVVISVLTTR -NDPAAKYDDALVAEAARIAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. CF418 TaxID=1855287 RepID=A0A1M7NHL3_9BACT -----RKKIQEIAQTAHGHVGMAMMSLEDGDTI-TLNGKDRFPMQSVFKLPLAIAVLDQVD -KGKFALDQVIHIRKEDLLPWSPMREKFPEGTMKLSDILAYTVSQSDNSGCDLLFRLVGGT -TYVEEYIHSLGVDSIAIRATEEQAAKAWEVQYTNWSSPVAMLQLLKGVHTGKYLSKSSND -FLLKIMKETTTGPGRMRGLLPKEAVVAHKTGTSDTAATNDVGIVTLPNGKHYAIAVFVSD -TKANTATREAVIAQLTRLFWD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. SolWspMP-sol7th TaxID=1839776 RepID=A0A1C4NIJ5_9ACTN ------AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGSGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRQLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERAAEADDQLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium quisquiliarum P25 TaxID=1329909 RepID=T0GI04_9SPHN ---------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE -AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP -EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPESAA -RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR -PTVEGKAAESAIADAARAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium phosphoreum TaxID=659 RepID=Q5MJG5_PHOPO ---QIEPALTNIEQQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMIKQSDILSYAPVTTDRVGTSMTLAQLCDATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDDTTRLDRIEPNVNNVSAAELRDTTTPIAMNSTLYSLLYSHALSETART -QLKQWMMDNKVSDSLLRAALPVGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNAAIAKIGQLIFTH- ->[subseq from] Beta-lactamase n=2 Tax=Auraticoccus monumenti TaxID=675864 RepID=A0A1G6Z5U4_9ACTN ------DRLAELEAANDLTIGVWARNLRTGAEL-AHRADTLFPMCSVFKTLAVAAVLSLVS -PDPRVLRRPVHIPPANMVDYSPFVEECADRGPTVEQLCVATLQLSDNTAANELMALTGGP -ASITRMARRLGDDVTRLDRWEPELNSAEPDRVTDTTSPRAIGRTFTSLLTGRGLRPRERE -RLTGWMLGNQTSAARLRAALPAGWTLADKTGGSGYAVNNDVGVAWAPDGTPLALSVLVRS -DDPEAVRDDAVVAAAGRICVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sulfitobacter geojensis TaxID=1342299 RepID=UPI0009ED4065 ----LGVEIRALEKRHDARIGVMVRHPASGWYW-GYRENERFLMNSTFKSVLCAAILYQVD -RQVLDLNTKIKISGQDILHYAPVTKKNIGSALPISDLCFATLDQSDNTAANLLINLLGGP -KGVMTYLDRINDAVTRLDRIEPSLNDFVAGDPRDTTSPAAMTATWQKMLTGDALRPTSRA -QLAEWMRHGSVTQEFLRKSAPIGWQIIDKSGDGRKHTRSIVAMMTPLAAAPYFVAIYVSD -TPASWVERNAIVAEIGRAIID-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A2W6RP40_9CAUL --------LSDLEARHGGRLGVAAFDIGSQRRV-SWRGQERFPFCSTFKAFLAAATLERVQ -RDEEQLDRAVAVVRADLIPHAPVTERAVGRTLTIRQLMQAAVEVSDNPAANILIREMGGI -AVWRSWWPRFGDTTTLISRLEPDLNTALPNDPRDTCLPDQTVANIRELAFGDRLTPEHDQ -MIQGWMTASPTGPNRIRAGAPAGWTIAHKTGTGANGTGNDIGMAIPLSGSPIVLATYFTG -AAATEDQRDAVISEATRRVFR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. (strain SPB78) TaxID=591157 RepID=D9UN36_STRS3 ------AEFTALERRYGAHLGVHAVDTGSGREV-AWHADTRFSYNSTFKALLAGAVLKKHG ---LAGMDHVLRYDKKDLVANSPVTEKHAGTGLSREALCDAAIRYSDNTAANVLLADLGGP -RALGALVRTTGDRVTRMERVEPLLSRWTPGETHDTTTPRRLTANLRAYTLGDVLAAPERE -RLTGWLRANTTGDATIRAGVPKGWTVEDKTGTGSHGARDDIAVIRPPGRAPLVLTLLSYR -DERAAEADDKLLAEATQVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A031JGZ5_SPHPI ---------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE -AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP -EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPASAA -RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR -PTVEGKAAESAIADAARAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Aeromicrobium massiliense TaxID=1464554 RepID=UPI0006760A52 --------LRDLERRHDARLGLLAVDTGTGTVV-AHRPDERFAHASAGKLLLAGAVLERRG ---TVGLDERVRVP-DETVPHSPVTESRTGRTLTWAEVLDAALRLSDNTAANLLAQDAGGP -DAVTEVLRAWGDDVTRVDRLEPDVNTAVPGDERDTSTPRVLAGHVRALVLGDRLAEPARE -RLVGWMRASTTGTALVRAGVPSGWAVADRSGGAAYGSRHDLAVVWPPHGAPLVLAVMTSR -RGQDDEGRDALVAQAAGVAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. EV170527-09 TaxID=2603411 RepID=A0A5B0IEJ9_9PSEU --------MADVERTYARTIGVHVLDTGTGRSA-GHRDGDRFLMCSVTKALMAGFTLHRSL -SDPGLLDRPVRYGRADLLEYAPVTTRNLATGMTVAQLCEAAVTVSDNTAHNLLLREVGSP -AELTAWLRTTGDTVTRSDRAETALNDR--DGERDTSTPAALASTLRTLVLGDALPAPQRD -RLAGWLRANTTGDRQIRAAVPADWGVGDKTGSGPLGERNDSGVLYPPDGAPLVLTVFTLP -ADADEQRGEDAVAAAARAAVA-- ->[subseq from] class A beta-lactamase n=3 Tax=unclassified Burkholderia TaxID=2613784 RepID=UPI00141E73A6 ---TAQAELAALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVVAAAAMLARGS -LDASLLPRRILYRRYEIVSGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTSFARESGATSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGDTLQEPQRT -QLTEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAVLWPPSRAPIVMAVSF-- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A7KEG2_KLEPN ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVA---------- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. D43FB TaxID=2017595 RepID=A0A2A3MRG8_9SPHN ---------KEIEQETGGRLGVALVDKQGALLL-GFNRDEPFAMCSTFKGPLAAAVLIGAK -GGKFGLEGEISFSKDDILDYAPVVKANRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPELNENAEGDPRDTTTPAAMAGLMGRLLFRDM-QGESAE -RLRGWLNASSTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGDEYILAVYLDR -PTVDAKKAEAAIAETARAALE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia sp. BL23I1N1 TaxID=1938802 RepID=A0A420A2M6_9BURK -------PLADIEHRNGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGMLAAQILARVD -SGSEQLDRLVHYTEKDLIFTSPVTKANVARGMSIDALCRAVLVESDNTAAILLMRSAGGS -AALTRFARGLGDTVTRSDRDEPDSNRY--DGELDTTTPRAIATTAQRLLLGDVLSASSRV -QLERGMTDCRPGLNRIRAVLPAGWQAADRPGTSVERETNDYALVRPPGQAPLLVAVYYDA -PGVSMDAREAVLREAGAALL--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium quisquiliarum TaxID=538379 RepID=UPI000688A29C ---------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE -AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP -EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPESAA -RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR -PTVEGKAAESAIADAARAAL--- ->[subseq from] Uncharacterized protein n=3 Tax=Frigoribacterium TaxID=96492 RepID=A0A0Q6B597_9MICO ---EVEAALADLESRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLEATD ---DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -AGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFTATLARITDGDWLAADDRA -TLLEWMSRNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAARYDDALVASVAEVAL--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. DC-2 TaxID=1303256 RepID=UPI0009DEF370 ---------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE -AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP -EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPESAA -RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR -PTVEGKAAESAIADAARAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio toranzoniae TaxID=1194427 RepID=UPI001378F31E -------------EKLGWSIGVTVLETDNGEKE-SIHGDKRFHFNSTIKALACANILEKSD -KNIISLDDSIKLKKGDIVTYSPVTKDYVGRNLTLKQACDATLTYSDNTAANYTISAGGGP -NGLTKFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMTSSLNKILLGNVLSDSSKK -QLRAWMEGNKVADNLLRVSLPSGWSIADRSGASDYGVRGIIALAWSESNSPVIIAMYVRK -EGTSMAERDQVIADLGHVIFDKy ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter colistiniresistens TaxID=280145 RepID=N9PKQ7_9GAMM ---ALEEQVKSL-SEKGWQVGVSILDME-NKRI-SINGDKRFPLDSTVKALACAHVLAQVD -AKKLTLDHSKTIRQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNDSMKKLLMGDVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWAENHAPVFISIYVRK -SETSLDERSAVIKLLSEHIVKE- ->[subseq from] Class A beta-lactamase n=2 Tax=Legionellales TaxID=118969 RepID=A0A3B9RW06_9GAMM ---SIQEQLAELEVSSKGRIGIYVINTANNTHI-GYRADEHFPMGCTAKVIGVAAILNQSM -NQHDLLSQKISYSTNDLTNWSPITKQHLATGLTIKQLCAAAISFSDNTAMNLLVKQMGGL -NEMTHFAHTLGNTSFRQDNNWPEAYSGGKDNLDDSSTPKDMADSLQKLAFTDALAKPQRE -MLVSWLKANTTGDFRIRAGLPKVWAVADKTGTGGYGTTNDLGIIWPPKCAPIVMVIYYTS -DDKTAKKRDDIVASATQLLIS-- ->[subseq from] Beta-lactamase n=1 Tax=Plantibacter sp. PA-3-X8 TaxID=2480625 RepID=A0A3G8VNF0_9MICO ---DLSGEFQALEAEFGARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR ---GSARDEVITWSAEDVEAYSPVTSEHVETGLTLSQLAEAAVRQSDNTALNLVLARIGGP -AALDAALVTLGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFTDNLTRLVDGSYLESADRA -TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT -LDPDAEYDDALVAEAASVALAAf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=D2KNX6_STAAU -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Actinokineospora terrae TaxID=155974 RepID=A0A1H9X8W8_9PSEU ------------------------MDTKRDRTV-SYQADERFAYASTSKAFAAALVLDATT ---PQQLEEPVPIRAADLVANSPVVERAVGGTMTWRELCDAAVRYSDNAAGNLLLRSLGGP -AGLQA---GLGDQVTSADRYEPDLSSAIPGDPRDTSTPRTMATNLRKFTVDTALPEEDRA -MLDDWLRNNTTGTDVIRAGVPRDWVVGDKTGSADYGGRNDIAVLWPPGRDPIVIAVLTSR -DKEGAERLDALVADTARIVA--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=UPI00068C5E4E ---------REIEKESGGRLGVALIDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAE -AGKFGLDGQVAFSKSDLQNHAPAVKANIKRGMSMAELAEAAVELSDNSAANLLLPFVGGP -EGLTAFMRSHGDAVSRLDRNEPGLNENAQGDERDTTSPAAMAGLMARLLFQDM-QPASAA -RLREWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALIKAPSGEEYILAIYLDR -PTVEGKAAESAIADAARAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium helvum TaxID=1534349 RepID=UPI00138B8AED ----VEQRIADLEKRHNAFVGLYGQNLASTVSL-AHRDGDPFAMCSTFKAYLSARVLQKAQ -VGELRLTDTVAVDPDLLRPNSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDERTRLDRWETELNSALPGDPRDTSTPRALGGGTLTVLTGSVLDEPHRK -QLEDWMRANTT--SSMRAGLPTGWTTADKTGSGGFASTNDVGIAFGPNGERVLLAIMTRT -RSANAPALRDLIAEVTTVA---- ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. B-7 TaxID=1298855 RepID=UPI0003B6E910 ----TANPIAEYEHTTGGRIGVHALNVTTGQTL-SWRADERFIMCSSYKASLVAFVLARID -RGQEKLDALVPYTAQDTLGWGPIAKENLAKGMTVAAMCKAAVEISDGVCANMLLARSGGP -AALTAFLRSIGDTTTRVDHFEPALDRVPSGGPDDSTTPAAMASTLQKVVLGDVLAARSKG -LLTRWLIGNQT-NPRLRGGLPQSWRIGNKTGHSGRDMAGDIAVAWPHPGMPIVIAVYTRG -GRPTEAQFDKAFAGIGRLVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C10E7E ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BD0475 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAALREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium algorifonticola TaxID=2008318 RepID=A0A437J745_9SPHN ---------RKIEAATGGRLGIALVDREGNLLI-GFNREERFAMCSTFKAPLAAAVLMGAE -KGRYGMDGTLPVTQADLLDYAPVVKANLKKGMAIADLAKAAVEVSDNSAANLLLPLVGGP -DGLTAFLRAHGDALTRLDRTEPALNENAPDDPRDTTSPVAMATVMARLLFQDM-PAAAAA -RLRGWMEASSTGAARIRAGTPADWTVGSKTGTCGT-AYNDVAILRSPSGRDYVLAIYLDR -PTVDAKAAEAGIAEAARAAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Legionella yabuuchiae TaxID=376727 RepID=UPI0010556AAB ---SIQKKFAELEASSKGRIGIYAINTANHTHL-DYRANERFPTGCTSKVIGVATILSQSM -NDPTLLSQRISYSKNDLTHWSPITKKYLSSGMTVEQLCAASISYSDNTAMNLLVKKMGGL -EQMTLYARSLGNNSFRQDNWPEEAYSGGKGNLKDSSTPEDMAKSLQKLVFTDVLAKPQRK -MLMAWLNANTTGDFRIKAGLPKGWRVADKTGTGGYGTTNDLGVIWPPGCDPIIMAIYYTS -DDKLAEKRDDVIASSTRLLIN-- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus kloosii TaxID=29384 RepID=UPI000D1E1187 ---SHADELKNLEKKYNANVGVYALDTKSGKEI-KFNADKRFAYASTSKAVNSAMLLEQVP ---YDKLDKKVHINKSDIVDYSPVLEKYVGKDITVKELIKASMMYSDNTANNKIIDELGGY -KQIRKNLKELGDNTTQPSRYEPDLNNYSPKDKRDTSTPKAYGKTMKKLIEKDDLSKKNKD -FLLDLMFNNKNGDTLIKDGVSKKYKVADKSGQATYASRNDIAYVYPKGQKPIVLVIFTNK -DDKNAKPNDKLISETAKKVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429AVH0_9ACTN ---EVKEQLRALEVSYRGRIGAYAIDTGTGKTL-SYRGGELFPSRSTFKAILCGAILTKAR -TDPGLLQRTLHWTAQEVVANSPISEENVKNGMTVDRLCHAAITVSDNTAGNVLLKQIGGP -AGLTRYYRSLGDPVGRLDRWEPELNDWKPGEKRDTVKPAFMARSLSKLTVGDTLEPKDRQ -RLNEWLRASTTGPERIRKGLPSTWTVGDKTGGAAYAPGSDIAVAWPPTGAPLIIAVYTNR -DDPAATMDDSVIAKTATFL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium aquimaris TaxID=512643 RepID=A0A2T3IHT0_9GAMM ---QISPELAKIEHQLGGTVAVAVYNANTNTSW-NYHGEQRVPMMSTFKTLACADLLHQAD -TQRIDLNQAITIKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDKITRLDRIEPNVNNVSTAELRDTTTPIAINSTLYHLLYTDALSTSARK -QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMAELNTTIANIGQLIFQH- ->[subseq from] class A beta-lactamase n=1 Tax=Legionella spiritensis TaxID=452 RepID=UPI000F6D285B --kTLPQQLQQIEQRNGGRIGISVLNTGNQHQI-NYRANQRFPMGCTSKVIGVSAVLNKSM -TDPMLLGKKITYQTIDLASWSPVTGKHVKDGMTVEALCSAAIRYSDNTAMNLLVKELGGL -EAINAYAKQLGDHQFRQDNIWPDEAFSGGDDPYDSSSPAAMTNNLRQLLLERGLGEKQHK -LLQSWMLSNTTGDKRIRAGVPASWKVADKTGTGAYGTTNDIGVIWPGACSPIVMSVYFTQ -NRKHATPNDRVIVDVTKSVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_008 TaxID=1898736 RepID=A0A1S2HEQ8_9MICO ----VDRALAALETEYDATVGVVATDTVTGESV-THDGDHRFGYASTVKAFAAAQFLRSVR ---GSDRDEVVHWTAADVAAHSPVTEQHVGDGLSYAALAEAAVRQSDNTALNLVLTRIGGP -SGLDAALHDLGDDVTQVVHDEPDLNTIEPGSTEDTTTPAAFAADVAAVLDGTTLDTADRA -QLLDWMGGNATGDTLIRAGAPEGWTVADKSGGAG-GIRNDVALVTRPGGDPIVIAVLTTR -NDPDAAYDDALVAKTASVVLGAf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=A0A252AYJ0_9PROT ------KALADYESRTGGHIGFFAQNVVTGASL-GWRASERFVMCSTFKASLAACVLSRID -QGHDTLETTLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP -SALTAFWHALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSALSRA -LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWAKSDTPLLVSAYTRG -GKPTETDFATAFAAIGSLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. CIP 64.2 TaxID=1217694 RepID=N9N3L4_9GAMM ----LEEQVKSL-SEKGWQVGVSILDME-NKRI-SINGDKRFPLDSTVKALACAHVLAQVD -AKKLTLDHSKTIRQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNDSMKKLLMGDVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWSENHAPVFISIYVRK -SETSLDERSAVIKLLSEHIVKE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A212MHV5_KLEPN ---------------AVGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIA--------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Frigoribacterium sp. ACAM 257 TaxID=2508998 RepID=A0A5C6PY07_9MICO ---DVADDLAALEAEFDARVGVSVVDTGTGATV-SHRADERFGHASSLKALAAAQFLHDVP ---VDQRDEVVTWTAGDVEAYSPLTSEHVADGLPLAQLAEAAVRQSDNTALNLVLDRIGGP -AGLDRGLDDIGDSTTEVVNREPALNTIEPGSTDDTTTPAAFAADLVALLDGRWLDDADRS -LLLDWMSGNATGDTLIRAGAPAGWVVADKSGGAG-GIRNDVAVVTPPGRAPVVVTVFTAR -NDPDARYDDALVARAASIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Listeria rocourtiae TaxID=647910 RepID=A0A4R6ZHN1_9LIST ---KFKSEIEKLEKKYGATLGIYGMNTENKQTI-SYNAQERFAYASTFKAIAGGILLKNLT ---DDELNKRFYFSKEDLVDYSPVTEKHIDSGMTMKELIQAAMDYSDNTAANIMLRELGGP -EGFKKELLKIGDKTMLPVRYEPELNEAVPGDTRDTTTPEAMANSLSFLLTKGNMAEDRLH -LFKQMLFDNTTGDNLIRAGVPKGYIVGDKTGAGWYGTRNDIAAIYKDDAKPLIWVIYSKK -TGRDDEYNDQLIADAAKVLSDYf ->[subseq from] class A beta-lactamase n=1 Tax=Listeria riparia TaxID=1494964 RepID=UPI00068D17CA ---QAKEALKQLEKKYGSTLGVYAVNPKTSHTL-QYNAQERFAYVSTYKAIASGVLLKNLT ---EQQLEKRVFFKKEDLVDYSPVTEKHVESGMTIKEIIHAAVAYSDNTAGNLLFNALNGP -KGFQDELRKIKDETTNADRYETELNVAVPGDPRDTSTPEAFSKNLAFLTRQGNLQPKQLD -YFKQTLIENTTGGKLIRAGIPKDYIVGDKTGAGSYGTRNDIAVIYSDDREPLVWVIFSKK -DKEDATYDDQLIADASKVLSQYf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011F326D1 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKTGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. AP49 TaxID=1144307 RepID=J2WQ64_9SPHN ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAE -GGKFGLDGEIPFTKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -EGLTAFMRAHGDKITRLDRNEPALNENIEGDGRDTTSPAAMAGLMSRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDQKAAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Plantibacter sp. Leaf314 TaxID=1736333 RepID=A0A0Q5EMH8_9MICO -----SAEFQALEAEFGARVGVSAIDTGSGARL-SYRADERFGYASTIKALAAAVFLHEVP ---AAAREELVTWSAEDVEAYSPVTSEHIDTGLTLSQLAEAAVRRSDNTALNLVLARIGGP -SGLDAALAALGDEVIEVVNAEPTLNVIEPGSTEDTSTPAAFADDLSRLIDGSVLEPADLE -TLLTWMSGNATGDTLIRAGAPADWPVADKSGGAG-GIRNDVAIVRPPGREPIILSIFTNK -LDPDADYDDALVAAVAKAALSAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00090FFB71 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKQNDKLISETAKSVMKEf ->[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. MCBA15_019 TaxID=1898745 RepID=A0A1S2IFB6_9MICO ---EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD ---DADLDRVVTWTQSEVDVYSPLTGQHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -TGLDAALAAQGDDVSDVVHSEPELNTLTPGSTADTTTPAAFTATLARISDGNWLAADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAAKYDDALVAEAARIAL--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter cibinongensis TaxID=146475 RepID=A0A1Z5YWG7_9PROT ---QLTTALDEFEVQTGGRVGVYAKNLVTGQCL-AWRETECFLMCSTFKASLVALVLLRID -QGKEELENFVPYTQEDLGEYAPVARAHAASGMSVRSLCQGAIEQSDNVCANLLLARVGGP -TALTRFWRSLGDEVTRLDDWEPALNSTPLTEGRNTTTPATMAGSLEKILFSELLTDASRT -LLTEWLQQCRTGIKRLRLGLPQNWSVGDKTGTNGKDIAADIAVVWPVPTTPLIMSVYTRG -GHPTEQQFQSIFSNIGRLVRH-- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A3A9EC8 ------KALADYESRTGGHIGFFAQNVVTGASL-GWRASERFVMCSTFKASLAACVLSRID -QGHDTLETTLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP -SALTAFWHALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSALSRA -LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWAKSDTPLLVSAYTRG -GKPTETDFATAFAAIGSLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=D2SSQ3_PSEAI ---DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID -AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP -PLLTKYFRSLGDKVSRFDRIEPTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG -QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA -PELQGEERALLIASVAKLAR--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. AEW013 TaxID=2572915 RepID=A0A560XKY5_9SPHN ---------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMLGGP -QGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTTTPAAMAELMGRLLFRDM-KGESAD -RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAQSAQAALD-- ->[subseq from] Beta-lactamase n=1 Tax=Blastomonas sp. RAC04 TaxID=1842535 RepID=A0A1B3N9D0_9SPHN ---AIARELAAIEARSGGRLGVALVGPDGHQLA-GHRADERFAMCSTFKLPLAAMVLENAH -KGRLSMADPLPVTDSDMVVYSPYVEAQRAKTVTVEGAASAAVSLSDNTAANLLLDRLGGP -QSFTAWLRGKRDSVTRLDRREPELNENALGDPRDTTTPAAMAETTRSLVVGNAMPVGQQR -LLYRWTENTTTGLKRIRGGLPQGWSAGDKTGSCGN-AFNDVAVFTAETGMRYTLAVYLDR -PAVKGDAASAIIADATRAVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2DW14_9ACTN ----LTTTLRKLETSYQGRIGAVGIDLATGRTV-GYRADERFPFNSMFKVFACAAVLHKAR -TDPGLMDRVVRWKPADMAANSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP -GGLTAFFRATGDRTSRLDRTEPTLTEWQPGEKRDTTTPAAAARTFAELTTGKTLHADDRA -RLVGWLKAGLTGADRIRAGLPKDWTVGDKTGTGGHGTANDVAIVWTPGSAPIILSVFTNR -NADNRPNDDKVIASTATALAK-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Betaproteobacteria TaxID=119066 RepID=A0A0N0JEA1_9PROT ---PLQEELAALEARSGGRLGVAVLDTASGASA-GHRADTRFGLCSTFKLLLAAATIERIE -AGAWPAQRRIAYTAADLVVHSPVLRERLAEGLTALQMAQATQETSDNAAANLLMRELGGP -AGLTAWLRRQGDTLTRMDRWEPEMNIVVAGDERDTSTPAAIAATSARLLTGPVLSPAGRE -QLAGWMVATRTGARRLRAGLPAGWKAGDKTGTAMPDRYNDVAIVWPGQRAPWLLAAYFES -RHRDRPEDEAVLADVGRLV---- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. PACM 27299 TaxID=1727164 RepID=A0A0P0NH37_9SPHI --nQLRNQIKQVIAHKKADVGVSVYGIESKDTL-SVNGDRHYPMQSVFKFHIAMAVLNQVD -KGKFSLSQKIHIKKSDLLPWSPIREAHPNGELPLSEIIKYTVAKSDNNGCDILMRLLGGP -KPINDYIHSLGVKDVAIQANEEEMHKEWNVQFSNWSTPKAITQLLVKFYTENLLSKESFN -FLWTTMVETSTGVNRIKGKLPKGTIVGHKTGTSDTAAINDMGIVRLPNGKHYAIAVFVCN -TKENEATNDKIISDISKLVWDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Caulobacterales bacterium RIFOXYB1_FULL_67_16 TaxID=1797588 RepID=A0A1F8IP10_9PROT --------LSDLETRHGGRLGFAALDVGSGRRV-LWRAQERFPFCSTFKAFLAVATLERVQ -RDEERLDRAVRVTEADLIPHAPVTGAAVGRSLTLRELMQAAVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPEQTLANIREMAFSDRLTPEHDA -LLHGWLTASPTGPNRIKAGAPEGWTVAHKTGTGANGTANDVAMLTPLSGSPVIVAAYFTG -ATATDDQRDAVIAEATRRALKAf ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Novosphingobium sp. Chol11 TaxID=1385763 RepID=UPI000BE23B11 ---------REIEKETGGRLGVALVDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLMGAD -AGRFGLEGQVAFTDADILDHAPVVKANRKRGLSMAELAKAAVEVSDNSAANLLLPMIGGP -EGLTAFIRAHGDTVTRLDRTEPLLNENMEGDVRDTTSPAAMAGLIARLIFRDM-KPESAE -RLRTWLNGSTTGDKRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYLLAIYLDR -PKVDGKAADAAIAETARAALE-- ->[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077PRS6_XENBV ----LKDKIKTLEAQ-GWQVGVSILDYNGNKIE-SVNGDERFPLDSTVKALACANILAKVD -NKSLRLEDSVLIKEKDIVTYSPITEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP -SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE -QLKEWMMGNKVADNMLRSELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYLRK -SNTSLEERSEKIAEIGMVIFSKy ->[subseq from] Beta-lactamase n=1 Tax=Oscillatoria nigro-viridis PCC 7112 TaxID=179408 RepID=K9VFX3_9CYAN --nELRDRIEQISQAALGRVGVTATVLETGESV-TLNGDGQFPMQSVYKFPIAMAVLDRVD -RGKLKLDQKIRVEASDVLQGSRILDEKSQGMFSLSELLKYMVSESDNTSCDVLLKLLGEP -KVVTEYLRGLGVNDIVVAQTEKELAQDTAAKYRNYATPDAAVALLRAFHEGKGLSKSSQA -LLLQLMTETTTGPKRIKGLLPDGTVVAHKTGTSSTAATNDIGLVTLPNGRHLAISVFVSD -SRANDAVREEVIAKVAKAAWDEw ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia jinanensis TaxID=382504 RepID=UPI0009E7C218 ---DLANTLMMLQAKYNVLFGIAAVDPRGGRAF-GWNTDDRFAMTATFTVYAVAAILRLAE -REELDLNDKVPITRSDIVLNSPDTSYHVGELMSYYELCRATLVRSDNTAANLLLRRLGGP -AAVTEFARSIGDVQTRLDRWEPELNEAQTGDPRDTSTPAALAAGYRKLILGDGLSTEYRR -MLTSWLRSSVTSRERLRKGLPVGWVAADKSGSGAYGTANDAGVVWSPTGSSLVLVILSRS -TTPMAAGADAAVADATAAVL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea vestrisii TaxID=151416 RepID=A0A543N2C0_9BRAD -------DLKSLEARHGGRLGLFATR--DGQRV-GWRSTERFAFCSTFKLFLAAYVMQTVQ -QGRDRLDRDVPITAADMVPHGPVTQPAIGRTLTLEELCKATVEVSDNPAANILIREMGGL -AAFQQWYGSIDDHVTRVDRLEIELNSALPGDMRDTTTAEQYVANLDRVLRGNLLSAAHLQ -LLTRWITETPTGAGRIKAGVPAGYTVGHKTGTGARGTHNNIGIIWPPSGPSILICVFFTG -AQATPGAIDAVVADATRQAMKAf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ubonensis TaxID=101571 RepID=UPI001128CAFD ------SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLERLVHYTENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio toranzoniae TaxID=1194427 RepID=A0A109D985_9VIBR -------------EKLGWSIGVTVLETDNGEKE-SIHGDKRFHFNSTIKALACANILEKSD -KNIISLDDSIKLKKGDIVTYSPVTKDYVGRNLTLKQACDATLTYSDNTAANYTISAGGGP -NGLTNFMRSIGDDVLRSDRYEPELTKNIEYDIRDTTTTNAMTSSLNKILLGNVLSDSSKK -QLRAWMEGNKVADNLLRVSLPSGWSIADRSGASDYGVRGIIALAWSESNSPVIIAMYVRK -EGTSMAERDQVIADLGHVIFDKy ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter indicus TaxID=374177 RepID=UPI001368AC7F ------EQLEKLQASIPGILGAYIIDCESGQGF-GINENKHFALCSSFKLSLAAMVLQKAD -RGEINLDQRVHYSEGDLLSYSPVTRENLAHGLTLEELAKAAQVASDNAAANILMREFGGP -QAMTQFWRNMGDTVSRLDKTEPDLNLVAPGDEHDTTTPEAMAHTLAKLMTGTVISESSRA -KLWAWMQETSTGLQRIRGGIPKGWPAGDKTGTSFEGNYADIAFVRPPNGPPLAITSYYRL -PNKSEPQSQAVLAKVGAIAAD-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000448456F ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000D7024A1 ----------------------------------------------------------RVD -AGQEQLGRRIHYSQNDLVKYAPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI000789B3FF --------LSGYERATGGHVGVYAHNIATGRKL-LWRADERFVMCSTFKASLVACVLSHVD -QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP -PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA -LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG -GTPTEPQFANVFAGVGRLVAR-- ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium aquimaris TaxID=512643 RepID=A0A1Y6KZ77_9GAMM ---QISPELAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TQRIDLNQAITVKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDKITRLDRIEPNVNNVSTAELRDTTTPIAINSTLYHLLYTDALSTSART -QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMAELNTTIANIGQLIFQH- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium shigaense TaxID=722731 RepID=A0A1Z4ELJ4_9MYCO -----DEQLATLEDRYNAKVGFHGLNLHTGRML-DYRADDLFATCSAFKAYVAGAILAKDQ -RGELSLNDPVFIDPAVLVPASTITEPHVGGYLPLSALCAASVRQSDNTATNLMVAMLGGP -GAVTEFARSTGDDRIWMVRWELELNSAYPGDPRDTSTPRSMGAGFSNMLTGDVFDDAHRA -QLWEWMSTITTGNNRIRAGLPPEWGVADKTGAGDYASTNDIGVAFGPSGERLILSIMTRT -RSEDTPALNALIADITRLAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BE2E4C ------SPLAEIERSNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLERLVHYTESDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAVLPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3P5G6W8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSA----------------------------------------- ------------------------ ->[subseq from] Carbenicillinase n=1 Tax=Morganella morganii TaxID=582 RepID=Q307S9_MORMO --qQVEQDVKAIEVSLSARIGVSVLDTQNGEYW-DYNGNQRFPKTSTFKTIACAKLLYDAE -QGKVNPNTTVEIKKADLVTYSPVIEKQVGQAITLDDACFATMTTSDNTAANIILSAVCGP -KGVTDFLRQIGDKETRLDRIEPDLNEGKLGDLRDTTTPKAIASTLNKFLFGSALSEMNQK -KLESWMVNNQVTGNLLLSVLPAGWNIANRSGAGAFGARSITAVVWSEHPAPIMGSPYLAQ -TQPPMAEGNDAIVKIGHSIFDVy ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=A0A2T3MH36_PHOLE ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVTADAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNSDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caledonica TaxID=134536 RepID=UPI0003AAF2D0 ----ADSPFSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQILARVD -RGAERLDRLVHYTEKDLVFTSPVTKANVARGLPIDALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTTPTAIATTAQRLLLGDALSASSRA -QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAAYYDA -PGVSMEAREAVLRAAGTAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2E9CK92_9SPHN ---------RSIEEETGGRLGIALVDSKGALIL-GFNRDDRFALCSTFKAPLAAAVLIGAE -GGKFGLEGEIPFGKDDILDYAPVVKKNRKRGMSMAELAQAAVEVSDNSAANLLLPMVGGP -EGLTAFMRAHGDSVTRLDRNEPALNENAPDDPRDTXTPAAMAELMGRLLFRDM-KGESAD -RLRGWLNASTTGDNRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PTVDAKAAEAAIAQAAQAALD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A4P8JIX7_ECOLX --------------------GVALIETADNAQT-LYRADERFAMCSTSKVMAAAAVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNE-------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9H0_SHISO -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQTDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNLADHVTRLDRWEPELHQAIPNDERDTTMPAATATTSRKPLTGELLTLASPQ -QLIDWMEADKVARPLLRSALPAGWFIADKSGARERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNTQPAETGASL---- ->[subseq from] class A beta-lactamase n=1 Tax=Plantibacter sp. Leaf314 TaxID=1736333 RepID=UPI0009E9BBF9 -----SAEFQALEAEFGARVGVSAIDTGSGARL-SYRADERFGYASTIKALAAAVFLHEVP ---AAAREELVTWSAEDVEAYSPVTSEHIDTGLTLSQLAEAAVRRSDNTALNLVLARIGGP -SGLDAALAALGDEVIEVVNAEPTLNVIEPGSTEDTSTPAAFADDLSRLIDGSVLEPADLE -TLLTWMSGNATGDTLIRAGAPADWPVADKSGGAG-GIRNDVAIVRPPGREPIILSIFTNK -LDPDADYDDALVAAVAKAALSAf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter sp. AR-3-6 TaxID=2541721 RepID=A0A4R5DX30_9BACT ---EFAKKIETISKEARGVVGVGIMDLKSRETM-VLNPSHKFPMQSVFKFPLAMAALDQVD -KGKFILSQKIHVTRQDVSPWSPLSKKYPEGEVTLAELLSYTVSMSDNNACDILFRLLGGP -KNVEDYIRTLGVKDIAIAATEEEMSKDWNVQFTNWSRPAAMLQLLDVFFKGKKLSKESND -FLWKIMTETTTGPNRMRGLLPKEARVAHKTGTSGTAASNDVGIMTLPDGKQIAVVVYVSN -AAADEKTRDAVIAQITKAAWDYy ->[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4II29_9NOSO --nELRDRLEQISQAAQGRVGITATVLETGETV-TVNGDQQFPMQSVYKFPIAMAVLAQVD -KGKLKLDQKIQIEASDIVQDSRILDENSQGRYSLAELLQYMVSESDSTACDALLRLIGEP -QRATKYLRDLGVDDIVIANTENEIQQDPSLQYRNYATPDAAVNLLRAFHQGRGLSESSQT -LLRQWMTKTSTGSNRIKALLPEGTVVAHKTGTSATAATNDVGLVTLPDGRHLAIAVFVSD -STANNAIREEVIAKVTRAVWDEw ->[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=Legionella spiritensis TaxID=452 RepID=A0A0W0YX14_LEGSP --kTLPQQLQQIEQRNSGRIGISVLNTGNQHQI-NYRANQRFPMGCTSKVIGVSAVLNKSM -TDPMLLGKKITYQTIDLASWSPVTGKHVKDGMTVEALCSAAIRYSDNTAMNLLVKELGGL -EAINAYAKQLGDHQFRQDNIWPDEAFSGGDDPYDSSSPAAMTNNLRQLLLERGLGEKQHK -LLQSWMLSNTTGDKRIRAGVPASWKVADKTGTGAYGTTNDIGVIWPGACSPIVMSVYFTQ -NHKHATPNDRVIVDVTKSVIA-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00103CB560 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKNITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Fischerella sp. PCC 9339 TaxID=1174528 RepID=UPI000362A41E ---ELYNRIEEISRTAQGRVGVALTVLETGEAV-SLNGDQRFPMQSVYKFPIGMAVLAQVD -QGKLKLEQRIRVEKNDFVSHSPIRDDNPQGVLTLAQLLKYMVSESDGTACDVLLKLVGGP -EVVMKYLRDLGINGINVINTEKEIGQDKSVQYRNWATPEAMIVLLRALHEGRGLSKSSQG -LLLRLMTETPTGLRRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLPNRQHLAIAIFVSD -STADDAAREEVIAKVARAAWDKw ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A2Z6ABP0_9SPHN ---------AEIEKETGGRLGVALVD-KTGALLlGFNRDDRFAMCSTFKAPLAAAVLTGAE -GGKFGLEGTIAFSKDDLLDYAPVVKKNLKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP -PGLTAFMRAHGDAVSRLDRDEPTLNENAEGDERDTTSPAAMAGLMGRLFFRDL-AAESAD -KLRAWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVKSPDGDEYILAIYLDR -PTVDAKKAEAAIAETAQAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Frigoribacterium sp. 9N TaxID=2653144 RepID=A0A653US38_9MICO ----VEAALTDLEARYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAVAALLDATD ---DADLDRVVTWTQAEVDAYSPLTSEHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -AGLDAALAAQGDDVTDVVHGEPELNRLTPGSTADTTTPAAFTATLARITDGDWLAADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIATPPSGAPVVISVLTTR -NDPAAEYDDSLVAAVAEVAL--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. HH130630-07 TaxID=1690815 RepID=A0A1B1ZKE2_9PSEU ---------DGLERDFGRRIGVHILDTGSGATA-GHRDGERFLMCSVVKSLMAGFVLHRSV -SDPALLDRRVRWGPADLLEHAPTTKLHLADGLTVAQLCEAAVTVSDNTAHNLLLREVGAP -ADVTAWLRATGDTVTRADRTETDLNDV--DGELDTSTPVALAGTLAGLTTGDLLPPAQRD -RLTGWLRANTTGDGQIRAGVPAGWGVGDKTGSGPLGEKNDSGVLYPPGGAPLVLTVFTVP -GDPDDERGAEAVAATTRAAVA-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=UPI0008046428 ---KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD -TGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLNEIGGP -KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI -QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE -TELSLQAREQLIAQISQLILYKy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA53CB ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGREPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000241E70C ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA74D38 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=3 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077MLN0_XENBV ------DKIKIL-EAQGWQVGVSILDYNGNKIE-SVNGDERFPLDSTVKALACANILAKVD -NKSLRLEDSVLIKEKDIVTYSPVTEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP -SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE -QLKEWMIGNKVADNMLRSELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYLRK -SNTSLEERSEKIAEIGMVIFSKy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004513FAE ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA1A13 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. HIX TaxID=1759074 RepID=A0A0W1EWB2_9SPHN ------DGLRDIEERAGGRLGFAVVDQKGRLIL-GSNDNDRFAMCSTFKLLLAGQVLRGAT -KGGPSLRTPLPFTKADIVFHSPYTEANLAAGLRLGFAAEQIVKVSDNAAANLILKATGGP -EAFTRRMREMGDEVTRLDRFETILNENAVGDPRDTTTPQAMAKSAAKIVYGDYLDPAHRQ -SLRQWMVDSQTGLGRIRAGLPAGWVAGDKTGSCGN-AYNDVAFVELPDGGKYIVAVYLDR -PKVEGAAANAIIAEVTRAIAE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004678E3F ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi lrivu.4.1 TaxID=1248232 RepID=X0NN90_PHOLE ---NIDSAIKHAEQKLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVTADAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNSDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEASIPERDKEIAKIGNAIFERy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005C275A6 ---SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000D726EAF ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNEKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. 'scallop' TaxID=2562582 RepID=UPI0013E1F2C5 --------LSDLEARNGGRLGFVVQDAATGRKL-GWRGDERFVYCSTFKMYLAAATLLRAQ -AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSVANLRRLFLDQALTAASRD -LLLQWMTDTPTGQNRLRAGTPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -AQATDDANAAVIAEATRRALK-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0008529C7B ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKRDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=A0A126RMF5_9SPHN ---------KEIETETGGRLGVALVDSKGALIL-GFNRDERFAMCSTFKAPLAAAILTGAE -GGKFGLEGQISFTKADILDYAPVVKKNGKRGMSMEELAAAAVEVSDNSAANLLLPMIGGP -EGLTMFIRAHGDTVTRLDRTEPTLNENVEGDERDTTSPAAMAGLMGRLIFRD-LKTESAG -KLRGWLNASTTGTNRIKAGLPKDWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDAKVAEAAIAETARAALD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A7KEG3_KLEPN ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVKWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMGDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVP---------- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000D1A7DF9 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Pseudofulvimonas gallinarii TaxID=634155 RepID=A0A4S3KVZ4_9GAMM ------DALAKLERQHGGRLGVCILDTATGAEL-RWRGDERFALCSTFKLPLAATVLRAVE -LGELDGNAPVPFGPADLVPHAPVVQARLDAGMTALELAEAAQLTSDNVAANLLLRQLGGP -AGVTESWRARGDDVTRLDRFEPAMNHVLPGEEHDTTTPCAMARHVAALVTGDLLSADSRD -LLRQWLVATDTGLRRLRAGLPPHWPAGDKTGTGIANKLNDVAVAWPPGRAPLVVAAYYES -RG--------------------- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD174EB ---SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077NJK5_XENBV ------DKIKIL-EAQGWQVGVSILDYNGNKIE-SVNGDERFPLDSTVKALACANILAKVD -NKSLRLEDSVLIKEKDIVTYSPITEGYVNKKITLKQACEATTAFSDNTAANIAISSVGGP -SELTKFMRSIGDNTTRSDRYEPDLTINPEHDLRDTTTPNAMSNSIRKLLTGNVLSEKSKE -QLKEWMIGNKVADNMLRSELPKGWFIADRSGASDYGIRGITSMVWSDKEPPLFISVYLRK -SNTSLEERSEKIAEIGMVIFSKy ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium sp. CECT 9190 TaxID=2006084 RepID=A0A1Y6MQ87_9GAMM ---QISPELAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TQRIDVNQAITIKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDKITRLDRIEPNVNNVSAAELRDTTTPIAINSTLYHLLYTDALSTSARK -QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMAELNTTIANIGQLIFQH- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA7EEEF ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENQK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio logei TaxID=688 RepID=UPI00068489F0 ---SLNDTIIALEKQTSGDIGVAVLDTKTNQIW-SYKGNQRFPMMSTFKTLACAKMLHDAD -KKIINKKTETAIAQKDLIPWSPITEKYVGKSISTEKACEATMLMSDNTAANIVLQQIGSP -SSLTAFLLLMGDSTTQLDRIEPTLNEAKKDDIRDTTTPIAMVNTINKLLLGNTLTTTDKV -TLKKWMMDNKVSDPLLRSILPIHWSIADRSGAGGYGSRGITAIIWHEHRLPLIISIYLTQ -TDLTLAERNDIIVHVGSALFSQf ->[subseq from] Beta-lactamase n=24 Tax=Staphylococcaceae TaxID=90964 RepID=Q2FC27_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=5 Tax=Staphylococcus aureus TaxID=1280 RepID=Q1XG18_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000F4BE746 ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---VGERDEVVTWTAADVEAYSPVTSESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -AALDRALEQLGDTTTDVVDEEPALNTIAPGGTANTTTPAAFTADLTAVALGEALPSADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDIAVVTPPGRDPIVLSVLTSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E10331B ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYLPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=UPI0008040581 ---KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD -TGILKKNATTTVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP -KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI -QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE -TELSLQAREQLIAQISQLILYKy ->[subseq from] Beta-lactamase n=3 Tax=Sphingomonadaceae TaxID=41297 RepID=T0HJ78_9SPHN ---------KMIEEETGGRLGVALVDSSGALIL-GFNRDERFAMCSTFKAPLAAAILLGAE -GGKFGLEGQVSFTKDDVLPYAPVVKQNLKRGLSMEELAAAAVEVSDNSAANLLLPMVGGP -EGLTAFFRAYGDTVSRLDRKEPDLNENEPGDPRDTTSPAAMAALMARLIFKDM-KPQSAE -KLRTWLSRSKTGDRRIKAGLPEGWTSGGKTGSCGT-AYNDVALVKSPSGAEYLLAIYLDR -PAVDEAKADAAIAETAASALD-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E3E70C0 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Bacillales TaxID=1385 RepID=UPI0004B12182 ----HAEELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia caribensis TaxID=75105 RepID=UPI0007201058 -----DSPVSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQILARVD -GGAERLDRLVHYTEKDLVFTSPVTKANVARGLSIDALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTTPKAIATTAQRLLIGDALSASSRA -QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLIAAYYDA -PGVSMEAREAVLREAGTAFV--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E093A21 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGKEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007697A91 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QCF3_9STAP ----SAQDLTKLEHKNDATVGVYGINTATGKTY-SHNADTRFAYASTFKAITSGLLLQQSS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNVIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -KQQDAKPQDALVAQAARQAIQ-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012B05A44 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKNGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E2E7ED ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Phycosocius bacilliformis TaxID=1445552 RepID=A0A2P2ECY7_9PROT --qTAAKSLKALEAEAGGRLGVSILDTSNGELV-GHRQNERFALCSTFKLILAAEVLRDID -LGLLQRDQFVSYNQSDMVPHAPVTQAHLAEGMRLIDLARATQVTSDNPAANLLIRLLGGP -QAVTRRFREAGDRVTRLDRYEPMLNLVEPGSQFDTTSPAAMARLVARYLIGDYLSDLAKR -SLTGWLVETTTGLRRIRAGLPSGWRAGDKTGTVVQDFYNDVAIIWPPSHRPLIVAAYYNP -AVSSNPLHEAVLASVGRIAT--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009100B1F ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQCLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00123E47F5 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=C6KFE1_PSEAI ---DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID -AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP -PLLTKYFRSLGDKVSRLDRIESTLNTNTPGDERDTTTPMSMAQTVSKLIFGDTLTYKSKG -QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA -PELQGEERALLIASVAKLAR--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium amiense TaxID=135719 RepID=UPI000A06963C ---------KEIEAETGGRLGVALVDSKGALLL-GFNRDERYPMCSTFKAPLAAAVLVGAE -GGKFGLEGTIPFGKEDVLDYAPAVKKNLKRGMSMAELAQAAVELSDNSAANLLLPMLGGP -EGLTAFMRAHGDTVSRLDRTEPELNENAEGDPRDSTSPAAMAGLMARLIFNDM-KPESAT -KLRGWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALVRSPGGDEYILAIYLDR -PTVDAKKAEAAIAETARAAL--- ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=D2JC69_STAEP ---SHTQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. OK269 TaxID=2135728 RepID=A0A3D9TFK9_9NOCA --------FGELEQREQARLGVYAIDLESGASI-DYRSNERFAFCSTFKVYAAGAVLAAVD -SGQLALTDTRTVTAASKVAESAVD-WPVDSAVTLGEFCAAALGRSDNTSGNFLIDAAGGT -AAVTEFARSLGDTEFRLDRTEPELNTAIPGDDRDTTTPESLGAGYRALLRGDVLADSWRD -QLLAWMGDTHTSDMRFRAGIPAGWTSADKTGTGSYGVSNDAGLLLGPDGREILLVVLSTT -TTSDAAAMNSLVADTTREVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Microbacteriaceae bacterium 3R27F9-B TaxID=2502222 RepID=UPI0010FA46BC ---EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD ---DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRQSDNTALNLVLAELGGP -AGLDAALAAQGDDVTDVVHSEPELNRLTPGSTADTSTPAAFTATLARITDGDWLAAHDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAATYDDALVAAVAEVAL--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium amiense TaxID=135719 RepID=A0A494VZP4_9SPHN ---------KEIEAETGGRLGVALVDSKGALLL-GFNRDERYPMCSTFKAPLAAAVLVGAE -GGKFGLEGTIPFGKEDVLDYAPAVKKNLKRGMSMAELAQAAVELSDNSAANLLLPMLGGP -EGLTAFMRAHGDTVSRLDRTEPELNENAEGDPRDSTSPAAMAGLMARLIFNDM-KPESAT -KLRGWLNGSSTGDRRIKAGLPEGWTSGSKTGSCGT-AYNDVALVRSPGGDEYILAIYLDR -PTVDAKKAEAAIAETARAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Citricoccus muralis TaxID=169134 RepID=A0A3D9LA08_9MICC ---STDRALTDLEERFSGRVGVYAVDTGTGEEV-QYRADERFGYASTHKVFSAAAVLAQSE ---PADLDQRIHYSAEDLVANSPIAEQHVETGMTLGQIIGAAISHSDNTAGNLLFDALGGP -EGLQDAVVRTGDETTSVDREEPELNEWAPGETRDTTTPRQAAENLRGYTLGDTLEPWARD -ELLAAMRASENSEGLIRAAVPASWTVGNKSGAGGHGTRNDLAVIERAEGAPLVVAVYTNL -DDPEGQFQDDFVAEAATVAVE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00067CDCED ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5HUE4_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVIKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00094B9A91 ---SHAQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCLR17_036 TaxID=2175620 RepID=A0A2W1W4F8_9MICO ---RVDRALAALEQRYDATVGVVATDTGTGATV-SYRADRRFGYASTIKVLAAAAFLRAVP ---AAERSAVAHWTQADVAAYSPVTEQHVADGLPLDEVAEAAVRMSDNTALNVLLDRIGGP -AALDAALADLGDTTTEVVHDEPELNTIEPGSTEDTTTPAAFAAVLDRVLDGRTLGRADTA -LLTDWMSGNATGDALVRAGAPDGWVVADKSGGAGP-IRNDVARVTRPDGDPIVIAVLTTR -NDPDEPYDEALVAESARVAL--- ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5G9D2_STAAU ---SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=5 Tax=Staphylococcus TaxID=1279 RepID=A0A6B5HE94_STAAU ---SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=18 Tax=Bacteria TaxID=2 RepID=E4PYK2_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002CC334D ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000852EAFC ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=69 Tax=Bacteria TaxID=2 RepID=BLAC_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005C7B221 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC58E11 TaxID=1608881 RepID=UPI0008A86526 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus caprae TaxID=29380 RepID=UPI000BA55854 ---SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKTLIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. dhg TaxID=2163016 RepID=A0A3B7D7C4_9VIBR ---KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD -TGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP -KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI -QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE -TELSLQAREQLIAQISQLILYKy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A3265ED ----HAKELNDLEKKYNAHIGVYALDTKNGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA84A61 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHIDKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DAA312B ----HSKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter sp. CFBP 8615 TaxID=2301718 RepID=A0A399T5W3_9MICO ---DVSAELQALEGEFDARVGVSVLDTGTGDSV-AYRSDERFGYASTLKLFAAAELLHDVP ---ADQRDEIATWSAADMEEYSPVTSAHVDTGLPLAQLAEAAMRESDNTAMNVILERIGGP -AGLDRALEELGDTTTEVVNREDELNRIEPGSTDDTTTPAAFTGALAGILRGDRLSDHDRA -ILLDWMSGNATGDALIRAGAPDGWTVADKSGGAG-AIRDDIAVVTPPGRDPLVVTILTTR -NDPERDHDDALVARAAEVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. DL592 TaxID=2675524 RepID=UPI00141F0DEA ----LNERIGMLESRHNAVVGLYGENLDAKQTV-AHREGDMFAVCSTFKAYLAARILQKAQ -HGELRMMDTLRVDPAAVLPNSPISGPKAGSSLPLDELCQAVLQRSDNTAANMLLTVIGGP -QAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRTLGGGFRAILTGDVLDPAHRR -QLEDWMRGNVT--SSMRAGLQPGWTSADKTGSGDYASTNDIGIVFGPNGERILLAVMTRT -RSPNAEPLRQLIAEVTTAA---- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000D72AC9E ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQAP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=57 Tax=Bacteria TaxID=2 RepID=D2JLJ2_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004B61EAE ----HATELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00124EFA79 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYETELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Aeromonas dhakensis TaxID=196024 RepID=UPI000F5293E8 ------------------------------------------PLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSALPGDARDTSPPRAVTERLQKLTLGSAPAAPQRQ -QIVGWPQGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus TaxID=1279 RepID=UPI000447F1B5 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069D1AAA ----HAKELNDLEKKYNAHIGVYALDTKSGKKV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000766D6C7 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKNDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas ginsenosidivorax TaxID=862135 RepID=A0A5C6ULI2_9SPHN ----AMDEISALERRYGGRLGVFALDLETGRTF-AHRKDQRFKLQSTFKGLLAALVLADVS -RGAEKLDGIVHFGKADLLPASPVTEDAVARGMTVRELCEAIMYRSDNTAANLLMTRRGGP -DRLTRFLRGLGDDVTRTDSYEGHMNGR--PAAFDTTSPQAIVKTVRTLLLGSALPPSSQR -QLETWMEGNVVGRTRLRAAFPSDWRSGDRTGTGD-GVCNDYAIARRPGRAPLVMSAYYAA -PGMRLLDQEAVIRSVGRTVVE-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. DS20 TaxID=1532555 RepID=A0A0P0CZ11_9CAUL --------LNDLETRWGGRLGVAALDVGSGVRA-LWRSQERFPFCSTFKPFLAAAVLQRVQ -RDEERLDRPVRITSADIIPHAPVTEKAVGRTLTIRELMQAAVEVSDNPAANILIREMGGI -GVWRSWWPTFGDTTTVISRLEPDLNTALPDDPRDTCLPEQTVANIREMAFSDRLTPAHDA -LLHGWLTASPTGPNRIKAGAPEGWSVAHKTGSGARGTTNDVGMLTPLSGSPVIIAAYFTG -AAATEDQRDAVIAEATRRVLK-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFB16B1 ---ALEKEIQRIAAAAQGKVGIAAVVIETGKTV-SLNGDDRFPMQSVYKMPIGMAVLRAVD -QGRLKLDQKVPVTKADYVGHSPLRDAHPNGTTTVRELLRYNVLESDGSACDVLLRLIGGG -PAVTAYLEQNGVKGVRVINTEKEIGSAEDVQYRNWATPNEALALLKLLHQGGSLSAESRK -LMLKLMTDTQTGLKRIRGLLPPGTAVAHKTGTSQTAATNDIGIVTLPDGRHLAIAVFVSD -ARAGSEQREKVIAEISKAVWDAw ->[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium sp. GV027 TaxID=2135689 RepID=A0A2T6LVZ1_9SPHN -------PMAEYERTTGGRIGVHALNVTTGQTL-TWRADERFIMCSSYKASLAAFVLARVD -RGEEKLDALVPYTAQDTLGWGPIAKENLAKGMTVAAMCKAAVEISDGVCANMLMARSGGP -AALTAFLRSIGDTRTRVDHFEPALDRVPSGGPDDSTTPAAMASTLQKVVLGDVLAARSKG -LLTRWLIGNQT-NPRLRGGLPQSWRIANKTGHSGQDMAGDIAVAWPHPELPIVIAVYTRG -GRPTEAQFDKAFAGIGRLVAS-- ->[subseq from] Beta-lactamase n=2 Tax=Cellulomonas carbonis TaxID=1386092 RepID=A0A0A0BQJ3_9CELL ----------------------FAVDTASGLTV-EHRADERFGYASTHKALSVAALLAELA ---PAELDAVVRWTADDVVAHSPVTQERTGTGMTWRELGAAAVTHSDNTAANLVLDRLGGP -AGFERALRDLGDDVTSADRVEAALNEVAPGDARDTTTPRALAAGLRSYLLDGALTPEDAH -LLLGWMRDSTTGAGLVRAGVPAGWDVADKSGGGSYGIRNDVAVVRPPGGEPVVIAVMTAK -DERAAEGDDALVARATEVVVQH- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A192Y4S5_PSEAI ---DFEHAISDLEAHNQAKIGVALVS-ENGNLIqGYRANERFAMCSTFKLPLAALVLSRID -AGEENPERKLHYDSAFLEEYAPAAKRYVATGMTVTEAIQSALQLSDNAAANLLLKEVGGP -PLLTKYFRSLGDKVSRLDRIEPTLNTNTPGDERDATTPMSMAQTVSKLIFGDTLTYKSKG -QLRRLLIGNQTGDKTIRAGLPDSWVTGDKTGSCANGGRNDVAFFITTAGKKYVLSVYTNA -PELQGEERALLIASVAKLAR--- ->[subseq from] Class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=A0A1B1EJP6_VIBNA ---KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD -TGILKKNATATVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNIVLSEIGGP -KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI -QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE -TELSLQAREQLIAQISQLILYKy ->[subseq from] class A beta-lactamase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012FA7295 ---ALQRRLRALEGAYEGRIGAVAIDLATGRTV-GYRAGERFPFNSMFKVYACAAVLAKAR -RDPGLMDRIVRWQPGEVMDNGPETKEYTDTGMTPAQLCRAGITKSDGLAGNLLLKQIGGP -SGLTGYFRSIGDRTSRLDRFEPHLTEWKPGEQRDTTTPEAAARSFTRITTGDALDTRDRE -RLVAWLRDSVTGAERIKAGLPKTWTVGDKTGTGGHGTANDVAIAWPPGAQPIIISVLTNR -TANGLPADQKVIAKTATALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QH29_9STAP -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQSS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pettenkoferi TaxID=170573 RepID=UPI00119D66B3 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QBZ5_9STAP -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQLSSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHNLQKLLTTDAVAPQQRK -FLQNLMFNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVAVIYPKHQKPIILVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5I6S2_9SPHN ---------AEIEKETGGRLGVALVD-KTGALLlGFNRDDRFAMCSTFKAPLAAAVLTGAE -GGKFGLEGTIAFSKDDLLDYAPVVKKNLKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP -PGLTAFMRAHGDAVSRLDRDEPTLNENAEGDERDTTSPAAMAGLMGRLFFRDL-AAESAD -KLRAWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVKSPDGDEYILAIYLDR -PTVDTKKAEAAIAETAQAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter festucae TaxID=110937 RepID=UPI0013191E81 ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---ADERDEVVTWTAADVEAYSPVTGESIDGGLSLAQLAEAAVRRSDNTALNLVLDRLGGP -AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLAAVALGEALPSADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDKIVLSVLTSR -NDPEAAYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Gemmobacter sp. HB-1 TaxID=2652247 RepID=UPI00124CB56A ---DLGATITRLETDLEARIGIQILDTATGWSW-GHRQDERFLMASTFKSVLCGGILQGVD -RGEISLEESVRIGAQ-VPRNSPVTSRYLGGSLSIARLCLATLDQSDNGAANLLIDRMGGT -QAVTAFLRGIGDSVTRLDRKEPEMNLFLPGDPRDTTSPAAMVASWQVLLTGDALAPASRA -QLIEWMSIGGVTGTLLRPSVPPGWQVADRSGGGRDHTRNIVAMLTPPGRAPFFVAIYLSD -TPANWSTRNAAVAELSAKA---- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011401E82 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHVNKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Microbacteriaceae bacterium J5903 TaxID=2528712 RepID=UPI001239F20F ---DVSRELQRLETEYDATIGVSAGEPATGRSV-AYRPDTRFGYASTIKLFVAAEFLRRVP ---ADDRKDVVTWSAGDVKAYSPVTADHVSTGLSLENLAEAAVRESDNTATNVLLDRIGGP -GGLDAALAQWGDDTTHVARAEPALNEVDLGRTDDTTTPAAFTGNLTQLLNGPILPPDDRA -LLLEWMSGNATGDALIRAGAPAGWTVADKSGGAGP-MRNDIAVVTPPGGDPLVLTVLTRR -NDASAAYDDALVAEVAAVVLSAf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter indonesiensis 5H-1 TaxID=1231340 RepID=A0A0D6N9I5_9PROT ------KALADYESRTGGHIGFFAQNVVTGASL-GWRASERFVMCSTFKASLAACVLSRID -QGHDTLETTLPFSAADIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP -SALTAFWHALGDTTTRLDAYEPELNRTPLDRLENTTTPTAMTSVLKAIALGPALSALSRA -LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAVIWAKSDTPLLVSAYTRG -GKPTETDFATAFAAIGSLVA--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD0C8A1 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFSKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI00028240B9 -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] Beta-lactamase n=1 Tax=Geitlerinema sp. PCC 7407 TaxID=1173025 RepID=K9S819_9CYAN ----LRDLLNEIAQAAQGRVGMTATVLESGESV-SLNGNERFPMQSVYKLPIAMAVLNQVD -QGNLKPDQKIRIEASDIVQGSQVLDENSQGKFSLSELLQYMVSESDNTACDVLLRLIGEP -QRVTEYLSSLGINDIVVANTEQELAQDPAVQYRNFATPDAAAVLLRTLQEGRGLSQSSQA -LLLQWMTETPTGLKRIKGLLPEGTVVAHKTGTSATAATNDVGLVTLPSGQHLAIAVFVSD -SQAADVIREEVIARMAKAAWDEw ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Leaf26 TaxID=1735693 RepID=A0A0Q4JFT1_9SPHN -------NPAEIEKETGGRLGVALVD-KTGALLlGFNRDDRFAMCSTFKAPLAAAVLIGAS -AGKFGLEGTIPFSGDDILDYAPVVKKNKKRGMSMGELAQAAVEVSDNSAANLLLPLLGGP -EGLTAFMRAHGDTVSRLDRNEPTLNENAEGDPRDTTSPAAMAGLMGRLFFRDM-KQESAE -TLRTWFNASSTGDKRIKAGLPQGWTSGSKTGTCGT-AYNDVALVHAPSGDEYILAIYLDR -PTVDAKKAEAAIAETAQAAL--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QE54_9STAP -----AQGLTKLEHKNDATVGVYGINTATGKTY-SHNADTRFAYASTFKAITSGLLLQQSS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] Beta-lactamase CARB-6 n=2 Tax=Vibrio sp. THAF100 TaxID=2587862 RepID=A0A5P9CPV8_9VIBR ---SLEQSLSKIEQEIKGQVGVAVIDTQSHNQW-SYNGNQRFPMMSSFKTLACAKLLYDVE -QKKLTLSQKIDVPESGLVNWNPITENFVGSKMSLQSVCAATMLMSDNYAANLALQQIGGP -SGLTAFLREIGDQKTRLDRYEPELNYVEKGAENDTTTPIAITQTIKRLLTGDVLSTGSKT -QLQFWMTNNMISDSLARSVLPQGWLIADRSGGGVKGSRALTAMVWKSDRKPLFIGIFIAN -SSSTLPEINQVVADISQLIFAQy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012ED141E -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A2D8FS96_9CAUL --------LNDLETRWGGRLGVAALDVGSGVRT-LWRSQERFPFCSTFKPFLAAATLQRVQ -RDEERLDRPVRITSADIIPHAPVTEKAVGRTLTIRELMQAAVEVSDNPAANILIREMGGI -GVWRSWWPTFGDTTTVISRLEPDLNTALPDDPRDTCLPEQTVANIREMAFSDRLTPAHDA -LLQDWLTASTTGPGRIKAGAPEGWSVAHKTGSGANGTTNDVGVLTPLSGSPVIIAAYFTG -AAATEDQRDAVIAEATRRALK-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000B593E32 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSIMKEf ->[subseq from] Beta-lactamase n=2 Tax=Rathayibacter oskolensis TaxID=1891671 RepID=A0A1X7PJL5_9MICO ----VSADLRALEAEFDARVGVSAVDTGSGAAI-THRADERFGYASTIKALAAAEFLHDVP ---VDQRDEIVTWSADDVEAYSPVTSQHVDGGLPLSELAEAAVRTSDNTALNLVLDRIGGP -TALDEGLTELGDDTTEVVDDEPALNVIEAGSTDDTSTPAAFTADLARILEGDRLTEEDRA -TLLDWMSGNATGDALIRAGTPSGWVVADKSGGAG-GTRNDLAVVTPPGRAPIVVTVFTSR -NDPEREYDDSLVARTAEIVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069E49F8 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTLKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004450649 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044FC9FB ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter TaxID=469 RepID=UPI0005C5B5A9 ----LEEQVKSL-SEKGWQVGVSILDME-NKRI-SINGDKRFPLDSTVKALACAHVLAQVD -AKKLTLDHSKTIRQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNDSMKKLLMDDVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWSENHAPVFISIYVRK -SETSLDERSAVIKLLSEHIVKE- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter colistiniresistens TaxID=280145 RepID=A0A558ERX5_9GAMM ----LEEQVKSL-SEKGWQVGVSILDME-NKRV-SINGDKRFPLDSTVKALACAHVLAQVD -AKKLTLDHSKTIRKKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEITRSDRYEPDLVINPEGDMRDTTSPNAMSDSMKKLLMGDVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGITSMVWSENHAPVFISIYVRK -SETSLDERSAVIKLLSEHIVKE- ->[subseq from] Class A beta-lactamase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8JRW2_9ACTN ---ELDKTLRELEKTYDGRIGAVGIDLATGRTV-GYRAGERFPFNSSFKVFACAAVLHKAR -TAPGLMDKVIRWKPADMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP -PGLTRFFRATGDRTSRLDRTEPTLTHWAPGEKRDTTTPAAAARTFAELTTGKTLHAQDRA -RLVGWLKASLTGANRIKAGLPKDWTVGDKTGTGGHGTANDLAIVWTPGSAPIILSVFTNR -NDDDTPHDDKVIASAATALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. G8 TaxID=1350776 RepID=A0A653NCX8_9CAUL --------LNDLEELNGGRLGVAALDVGSQRRV-SWRGQERFAFCSTFKAFLAVATLERVQ -REEEQLDRAVAVTRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTIANIRELAFSDRLTPAHDQ -LISGWMIASPTGANRIKAGAPEGWTVAHKTGTGANGATNDIGMLTPLSGSPVLLAAYFTG -APATDDQRDAVIAEATRRALK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000F478506 ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---ADERDEVVAWTAADVEAYSPVTSESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPTADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR -NDPEAAYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A1W5QG57_9STAP -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQLSSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHNLQNLLTTDAVAPQQRK -FLQNLMLNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVAVIYPKHQKPIILVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=7 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044A4E95 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium leiognathi subsp. leiognathi TaxID=658 RepID=B0KYV0_PHOLE ---NIDSAIKHAEQQLGAKVGVSVLNANGDSLY-GYNSEQRFPLMSTFKTLACAKLLHDNQ -ITKGMMDKTYPVTADAILDYAPVFKDKIGTEVSLKDACFATMTTSDNSAANFVLAHIGGA -EGVTKFLIDNSDNVTRLDRIEPLLNEATPGDKRDTTTPYAMNETITKLVLGDALNPASKA -QLTEWMKANKVSNGLFRSVLPQGWEIADRSGAGGYGSRGITAVVWNEQKQPLVISVYLTG -TEVSIPERDKEIAKIGNAIFERy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066DE950 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00129DD9EA ---SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYIGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio natriegens TaxID=691 RepID=UPI0003580C2A ---KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD -TGILKKNATAIVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP -KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI -QLKIWMQDNKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE -TELSLQAREQLIAQISQLILYKy ->[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium aquimaris TaxID=512643 RepID=A0A2T3HWI6_9GAMM ---QISPKLAKIEHQLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TQRIDLNQAITIKQSDILSYAPVTTDRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP -KSVTQFIRTLDDKITRLDRIEPNVNNVSTAELRDTTTPITINSTLYHLLYTDALSTSART -QLKQWMMDNKVSDPLLRAVLPAGWHIADRSGYDTYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMAELNTTIANIGQLIFQH- ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf8 TaxID=1735673 RepID=UPI0006FD5338 ---EVEAALTDLETRYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLDATD ---DADLDRVVTWTQAEVDAYSPLTSEHVADGLPLRQLAEAAVRKSDNTALNLVLTELGGP -AGLDAALAAQGDDVTDVVHGEPELNTLTPGSTADTTTPASFTATLARITDGDWLAADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAATYDDALVAAVAEVAL--- ->[subseq from] Uncharacterized protein n=1 Tax=Photobacterium carnosum TaxID=2023717 RepID=A0A2N4UMG5_9GAMM ---QITPELTNIEQHLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMINQSDILSYAPVTADRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP -QSVTQFIGTLDDKTTRLDRIEPEVNNVSKAELRDTTTPIAMNSTLYNLLYGHTLSETARI -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDNYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNTTIAKIGQLIFTH- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004528CBD ---SHAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Plantibacter TaxID=2624265 RepID=UPI0009E8C0D2 -----SAEFQALEAEFGARVGVSAIDTGSGARL-SYRADERFGYASTIKALAAAVFLRQVP ---AAAREELVTWSAEDVEAYSPVTSEHIDTGLTLSQLAEAAVRRSDNTALNLVLARIDGP -SGLDAALAAFGDEVIEVVNAEPTLNVIEPGSTEDTSTPAAFADDLSRLIDGSVLEPADQE -TLLTWMSGNATGDTLIRAGAPADWPVADKSGGAG-GIRNDVAIIRPPGREPIILSIFTNK -LDPDADYDDALVAAVAKAALSAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000E26EF36 ---SHTKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. QXT-31 TaxID=1357916 RepID=A0A1P8WUJ6_9SPHN ------DGLRDIEERAGGRLGFAVVDHKGRLIL-GSNDNDRFAMCSTFKLLLAGQVLRGAT -RGGPSLRTPLPFTKADIVFHSPYTEANLASGLRLGFAAEQIVKVSDNAAANLILKATGGP -EAFTRRMREMGDAVTRLDRFETILNENALGDPRDTTTPQAMAKSAAKIVYGDYLDPAHRK -SLRQWMVDSQTGLGRIRAGLPAGWVAGDKTGSCGN-AYNDVAFVELPDGGKYIVAVYLDR -PKVEGAAANAIIAEVTRAIAE-- ->[subseq from] Beta-lactamase n=3 Tax=Staphylococcus TaxID=1279 RepID=U1EQ46_9STAP -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] Beta-lactamase n=1 Tax=Komagataeibacter hansenii ATCC 23769 TaxID=714995 RepID=D5QCA1_KOMHA --------LSGYERATGGHVGVYAHNIVTGRKL-LWRADERFVMCSTFKASLVACVLSHVD -QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP -PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA -LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG -GTPTEPQFANVFAGVGRLVAR-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044AD3E1 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. PhB127 TaxID=2485176 RepID=UPI000F4B3EAF ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -VALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPAADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR -DDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00006E623E ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A1B1W3B6_ACIBA ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Paraburkholderia tropica TaxID=92647 RepID=A0A1H7ER90_9BURK ----ADSPFSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQILARVD -GGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTTPKAIATTAQRLLLGDALSASSRA -QLERGMADCKPGLNRIRAVLPAGWRAADRPGTSVESETNDYALVRPPGRAPLLVAAYYDA -PGVSMEAREAVLRAAGTAFV--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus argenteus TaxID=985002 RepID=UPI000504B6E8 ----HSKELNNLEKKYNANIGVYALDTKSGKEV-KYNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KTIKKRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD25FF5 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus auricularis TaxID=29379 RepID=A0A2T4M990_9STAP ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus kloosii TaxID=29384 RepID=A0A512QDF5_9STAP ---SHADELKNLEKKYNANVGVYALDTKSGKEI-KFNADKRFAYASTSKAVNSAMLLEQVP ---YDKLDKKVHINKSDIVDYSPVLEKYVGKDITVKELIKASMMYSDNTANNKIIDELGGY -KQIRKNLKELGDNTTQPSRYEPDLNNYSPKDKRDTSTPKAYGKTMKKLIEKDDLSKKNID -FLLDLMFNNKNGDTLIKDGVSKKYKVADKSGQATYASRNDIAYVYPKGQKPIVLVIFTNK -DDKNAKPNDKLISETAKKVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA23CA ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNTVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Frigoribacterium sp. JB110 TaxID=1434829 RepID=A0A1R4G5F2_9MICO -----DEELAPIEEEFHARVGVSVLDTGTGATI-DYRSEERFGFASTLKVFAVAEMLRQVA ---PEQRDELVTWTEETVADYSPITAEHVADGLTLAQLAEAALRDSDNAATNLILDRIGGV -EGMQAGLKRLGDSTTDVSDVEPELNEVVPGDTGNTTTPAAFTADLSALLRPEHLEPADRA -TLLEWMSGNATGDALIRAGAPADWAVADKSGGAG-AMRNDIAVVTAPGRDPIIVTILTEK -NDPDAAYEDEIVARVAEVVL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Rathayibacter sp. PhB93 TaxID=2485103 RepID=A0A3N1NN57_9MICO ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---ADERDEVVAWTAADVEAYSPVTSESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPTADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR -NDPEAAYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium carnosum TaxID=2023717 RepID=UPI00128E80B3 ---QITPELTNIEQHLGGTVAVAVYNANTNTSW-SYHGEQRVPMMSTFKTLACADLLHQAD -TKRVDLNQPIMINQSDILSYAPVTADRVGTSMTLAQLCNATMLTSDNTAANLVLNNIGGP -QSVTQFIGTLDDKTTRLDRIEPEVNNVSKAELRDTTTPIAMNSTLYNLLYGHTLSETARI -QLKQWMMDNKVSDPLLRAALPAGWYIADRSGYDNYGSRGITAAVWQQGKQPIMISIYLAQ -TGKPMADLNTTIAKIGQLIFTH- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA1614 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPFRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00026BF0AE ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium cloacae TaxID=120107 RepID=A0A1E1EZH0_9SPHN ---------KEIEQETGGRLGVALVD-GSGALIlGFNRDERFAMCSTFKAPLAAAVLLGAE -SGKFGLEGQVPFTKDDILSHAPVVKQNLKRGLSMGELAEAAVEVSDNSAANLLLPMIGGP -EGLTAFFRAHGDSISRLDRREPDLNENAQGDPRDTTSPAAMAGLMARLLFKDM-KPESAE -KLRGWLNGSKTGDRRIKAGLPEGWTSGGKTGSCGT-AYNDVALVKSPSGAEYLLAVYLDR -PTVDERKAEAAIAETAASALD-- ->[subseq from] Beta-lactamase n=29 Tax=Bacteria TaxID=2 RepID=D2J684_STAAU ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RPQ8_9BACT ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR08 TaxID=2035403 RepID=A0A2H5VNZ0_9BACT ---RLEQEIARLARIAGGVVGVAARHLESGRRV-ALNGAERFPMASTYKVPIAVQVLTKVD -RGELALDQMITLEPADLSPGSGTLSDRVPGVLSVRNLLELMLLISDNTATDVLLRVAGGA -EAVTARLRELGIEEMRVDRPTKHVIARFDEDPRDTATPEAMVALLEQIYRGRALKRETTE -LLLDILRRCRTGEARLKGLLPPGTEVAHKTGTIG-GTTNDVGILTLPGDGHVAIAVFVKS -SDKDVPTRERAIAEIARAVHDFf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseolinea soli TaxID=2321403 RepID=A0A385SJC6_9BACT ---RLRDEIARITASVSADVGVAVLNMDTGDTL-TLHGRGHFPMQSVFKFPLAIMVLHEVD -KGTLALDQKIHLRKEDMLLWSPMAEKYPEGNLALSEILRYTVSQSDNSGCDVLFRLMGGP -KKVNDFLRGLGITQITIAATETEMHQAWPVQFTNWCEPVAMVALLKQFDRGNILSPTSRE -FLWKIMVETSTGPKRIKGLLPEGTVVAHKTGTGDYNAMNDAGIIVLPGGSHVAVVVYISQ -TKKDIPRLELVIAQISRVVYDQy ->[subseq from] Beta-lactamase class A n=1 Tax=Janibacter indicus TaxID=857417 RepID=A0A1W1YKW7_9MICO ----TSDPVAALEDKLDSRIGLYARNLGTDATL-AHRADDREAMCSTFKTLAAATALRRG- ----IDLDRVIRYATSDLVDYSPITGER--RRMTVGELCDAAIRYSDNAAANLLLERIGGP -RGLTREMRRLGDRVTRLDRWETELNTAIPGDPRDTSTPRALATTYRRLTLGDGLTGSDRW -ALRGWLEANTTSVKTFRAGLPQGWWSADKTGSGSYGVTNCAGLVSAPDGTQIVFAALTRR -STTDATGHPDLMRSIAELIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Celeribacter ethanolicus TaxID=1758178 RepID=UPI000ADA5197 ---------QDRERELTARIGVCVRNLATGQVY-LHRAEERFAMCSTFKASLAALCLRESD -EGALDLGEALAFGAKDLLPTSPVTKAYVQAGLEIRSLCQAVVEWSDNTAANLLLARVGGP -ASVTRFFRDMGDPVSRLDRVEMDLNSNSPGDARDTTTPLAMAQNVQRMTMEGVLSERSRS -LLVDWMRNEQNAKNRIRAAVPRSWEVANKPGTTLNGAANDIAMLWAPEERAFAMAIYVDT -KKGNTPAAVSAIRGIAEVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Aquabacterium pictum TaxID=2315236 RepID=UPI001396C023 ----LARRLAGIERRSGGRLGVMVLPTGGSDRPwGWNADARFPLCSSFKLLLASMALHEVA -GGRLSLDERLPFTRANLIDWSPVTDSEADHGMTVGALCAATLATSDNTAANLVLARLGGP -AALTAYLRSLGDTVTRLDRNEPAMNRPGADPHWDTSSPRAMATTAQALMLGTGLPAPEQA -RLLRWMRASVTGGRRLRAGAASDWQVVTKTGTSNT-DSIDVGVLWPARRPPLVVAAFIRD -SQADGAVRDACLADVARLL---- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA881C1 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKQSEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Oceanicola sp. D3 TaxID=2587163 RepID=A0A5B8BMU1_9RHOB --------FELIEQEAQGSLGVLALDTATGRRA-GWRADERFPFNSTFKALLAGLVLERVD -AGAERLDRRIPIRAADILNYAPVTAAAQGNSLTIGQLCAAAVGRSDNTAANLLLDTLGGP -SGFTTRLAH---PDARIDAWEPALNTFAPGDPANTVTPSSMVSLMTGFLLEQRLSEASRA -QLLAWLRAASTGAKRIRAGVPSGWQVGHKTGTGPGGCCSDVAIIHPPQGAPLMLAIYVAG -SERPTARIEPLFAELTRIAC--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005E5108F ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIILVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase class A n=1 Tax=Rathayibacter sp. PhB127 TaxID=2485176 RepID=A0A3N2FZW5_9MICO ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -VALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPAADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR -DDPEADYDDALVARAAAVVL--- ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000068334F ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. CAP-1 TaxID=2676077 RepID=UPI0012BB1F70 ---------KEIEQETGGRLGVALVDSKGALLL-GFNRDERFAMCSTFKAPLAAAVLIGAE -TGKFGLDGQLSFTGDDILDYAPVVKKNRKRGMSMSELAQAAVEVSDNSAANLLLPMLGGP -DGLTAFMRAHGDSVSRLDRNEPDLNENAPDDPRDTTSPAAMAGLMGRLFFRD-LQPGSAE -KLRTWFNASSTGDHRIKAGLPAGWTSGSKTGSCGT-AYNDVALVKSPAGDDYILAIYLDR -PTVDAKKAEAAIAETAQAAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2L1J110_PSEAI ------------------------------SQI-LYRADERFAMCSTSKVMAAAAVLKKSE -GEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTND-------------------- ------------------------ ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002BB2E43 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC58B01 TaxID=1795299 RepID=UPI0008A58BE4 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISEAAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. KK2 TaxID=1855727 RepID=UPI00097E5710 ------DNIRDIEKRSGGRLGIAVVK-DDGQLLfGSNANDRFAMCSTFKLLLAGQVLRGAT -DGGPSLRTPLPLTKADIVPHSPYSEANLALGLRLGLAAEQIVTVSDNAAANLILKATGGP -EAFTRRMRDMGDAVTRLDRYEIELNENAVGDPRDTTTPQAMAKSAARLVYGDHLDPSYRK -SLREWMVASKTGLARIRAGLPAGWLSGDKTGSCGN-AYNDVAFVEAPDGGKYVIAVYLDR -PVVEGEAANAVIADVTRAVVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Gordonia sp. TaxID=84139 RepID=A0A3S0U7Q1_9ACTN ----ATAGLRELEVANRARIGVYARDLRSGKTV-VHRPDDSFAICSTFKAYLVARVQQLVE -RDELSLATRVYVDPGEIKTHSPVTQRYAGGPVDIGVLCRAAVQESDNTAANLLLRAIGGP -PGLTAFARSIGDERTRLDRWETELNSAIPGDPRDTSTPGALAGGFTAILAGDVLAVSRRQ -QLTDWMLANQT--SSMRAGLPAGWTSADKTGGGDYGSTNDVGLVMGPDGQRVMVAVMIRS -TGPEVPGYRPLVGEVTRAVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE44984 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A3S4HMN4_KLEPN ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPA-------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. M26 TaxID=1762962 RepID=UPI00073F7FB7 ----LDERIGLLEKRHNAFVGVYGQNLDADHTV-AHRDNDMFAMCSTFKAYLSARVLQKAQ -RGELRMTDTRMVDPTAVLPNSPITGPKAGGALSLADLCQAALQRSDNTAANMLLAVIGGP -PAITEFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRSLGGGFRAMLTGDVLDEAHRR -QLEDWMRGNVT--SSMRAGLQPGWTTADKTGSGDFASTNDIGIVFGPNGERILLAIMTRT -QSADAESLRPLIGEVTTLVL--- ->[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI000D1BACEE -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTERYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus argenteus TaxID=985002 RepID=UPI000B590722 -----AKGLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase OXY-1 n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A095F0N6_BURGA ----ADSPFSDIERRNGGRLGVFAIDTGSGRTL-SHRAEERFLMCSTFKGLLAAQIMARVD -SGAERLDRLVHYTEKDLIFTSPVTKANVARGLSIDALCQATLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPESNRY--RGVLDTTSPKAIATTAQHLLLGDALSASSRA -KLERAMTDCKPGLNRIRAVLPAGWQAADRPGTSVERETNDYALVRPPGRAPLLFAVYYDA -PGVSMEVREAVLREAGTAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus simulans TaxID=1286 RepID=A0A2X3QUF0_STASI ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVS ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044F2F88 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A291N1A3_SPHYA ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] UPI00143F05F1 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143F05F1 -----AKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. IBVSS1 TaxID=1985171 RepID=UPI000A2E859A ----LRRAIATIEHDAGGPIGVALLDTHTGARF-NHRASSRFPLCSTFKLLLAARLLHGAE -TGLWQLGERLPIRREDMLNNAPFSETRIGGSASLLEMAEAMCVLSDNPAANLALARQGGP -AALTAWLRSIGDTTTRLDRNEPEMNNETPGDPRDTTTPTAMLATSRALVEGRILSAAGRA -RLLGWMQASRTADTMIRAALPPGWAEANKTGAGSWRARNIVSRITPPGRRPIWVAAYLFA -AKSELAERNRHFVPLGRAIVE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00124E4FFB ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069FA75C ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Aquabacterium pictum TaxID=2315236 RepID=A0A480AX23_9BURK ----LARRLAGIERRSGGRLGVMVLPTGGSDRPwGWNADARFPLCSSFKLLLASMALHEVA -GGRLSLDERLPFTRANLIDWSPVTDSEADHGMTVGALCAATLATSDNTAANLVLARLGGP -AALTAYLRSLGDTVTRLDRNEPAMNRPGADPHWDTSSPRAMATTAQALMLGTGLPAPEQA -RLLRWMRASVTGGRRLRAGAASDWQVVTKTGTSNT-DSIDVGVLWPARRPPLVVAAFIRD -SQADGAVRDACLADVARLL---- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rudentiformis TaxID=359158 RepID=UPI00124D11AC ---NVTKELRKLETDYKGRIGAFAIDTGTGKTV-SYRANERFPADSTFKAPLCGAILQKAR -TDPGLLNRILKWTKEDVVPNSPITTWSPVGGLTVSQLCQATVTTSDNTAANLLLKQIGGP -AGMTRYYRSLGDKVGRMDRYEPEHSYWKVGDVQGTITPATMASNLQKMTLGSALAPQDRQ -QLLAWMRGNYTGNMHIRAGLPNNWLIGDKTGHGSYGTGGDIAVVQPPSGAPLILAIYSHR -NAEDGVSDPKIFGATASVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Paraburkholderia sp. DHF22 TaxID=2571748 RepID=UPI001316B713 ---TAHDALAAIERRHGGRLGVFALDTGTGRTL-AHRADERFLMCSTFKGLLAAQVLARVD -AGHDVPGDLVHYTASDLIFTSPVTKANLAHGMTVGALCRAILEESDNTAAILLMKRAGGP -AALTQFLRDLGDTVTRSDRYELASNDY--DGELDTTTPRAIATTARTILLGNVLSAASRA -QLEAGMVACKPGRNRLRAALPTGWHAGDRPGTSVARESNDYALVRPPGRAPLLVAAYYDA -PGTSMDAREAVLREAGGVF---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346QRV8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDATMPAAVATTLRTLLTGEVLTLASRP -QLIDWMGADKVAGPLLLSALPAGGCIADGSGPGER------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Ruania albidiflava TaxID=366586 RepID=UPI0009FEE7D9 -----ETELQNLEERTGRTIGLYATNLSTGREV-AYRHTEPFPMCSLFKVLAVAGLLTEHS -PYGDYWEEKIPFGPEDIVENSPITSAHQEREMTVSELADAALRFSDNTAGNLLLEELGGP -AAVTRFARRFQATATRLDRWEPELNEAEPGDLRDTTTPADIARLYQAFLVEGRLGQLGQT -RLRDWMLRNTTADERLRAALDGEYELADKTGAGEFGVVNDAGIVWRPDGSVTVISVLTRS -DSRSADNDNTVLVAAARAAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0001BE5B83 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKPLIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000446268E ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPDAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RND1_9BACT ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETSKSVMKEf ->[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI00143831CE -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIIMEQLGGL -DQLSSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHNLQNLLTTDAVAPQQRK -FLQNLMLNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVALIYPKHQKPIVLVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE28C69 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMKYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sandarakinorhabdus cyanobacteriorum TaxID=1981098 RepID=A0A255YG74_9SPHN ----LRRAIAAIEHAAGGPIGVSLIDTHTGARF-SHRANDRFPLCSTFKLLLAARLLHGAE -TSLWQLGERLPIRREDMLNNAPFSETRIGGSASLLEMAEAMCVLSDNPAANLALARQGGP -AALTAWLRSIGDTTTRLDRMEPEMNNETPGDPRDTTTPTAMLATSRALVEGRILSPAARA -RLFGWMQASRTADTMIRAALPPGWAEANKTGAGSWRARNIVSHITPPGRRPIWVAAYLFA -ARSELAERNRHFVPLGRAIVE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00129124C0 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Uncharacterized protein n=1 Tax=Frigoribacterium sp. RIT-PI-h TaxID=1690245 RepID=A0A0N0L0B9_9MICO ---EVESALADLETRYDARVGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAAPLDATD ---DADLDRVVTWTQAEVDAYSPLTGQHVADGLPLRQLAEAAVRQSDNTALNLVLTELGGP -TGLDAALAAQGDDVTDVVHGEPELNTLTPDSTADTTTPAAFTATLARISDGDWLAADDRA -TLLEWMSGNATGDTLIRAGAPDGWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAATYDDALVAEAARIAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012EE9BEA ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIITEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLNKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI00094F5CFB --------LSGYERATGGHVGVYAHNIVTGRKL-LWRADERFVMCSTFKASLVACVLSHVD -QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP -PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA -LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG -GTPTEPRFANVFAGVGRLVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Root1279 TaxID=1736443 RepID=A0A0Q7EDD6_9CAUL --------LSALEARHGGRIGFAARDLATGREL-RWRGEERFVYCSTFKMFLAAATLLRVQ -SGEERLDRAIPITRADMINHAPVTEPAVGGTLTIQDLMKGTVEVSDNPAANILIRELGGL -DVLRDFYRGIGDQTTTVDRLEPEMNRL--DGDKDTIQPVQAVANLYRLLVETPLSAESKA -LLLRWMTDTPTGVGRIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPSGEPVIMAVYNHA -TRSDEAQREATIAEAARLAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000AD86F67 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A2W4TK90_9PROT -------DLAALEARHGGRLGFAVRDTATGQAL-VWRGDDRFVYCSTFKMYLAAATLMRVQ -EGQERLDRAIPVTAADMINHAPVTGAAVGGTMTIEALMKGTVEVSDNPAANILIRELGGL -AEMQAFYRSLGDMRTRVDRLEPEMNRL--DGDKDTITPAQSALNIETLFVNSPLVQSSRQ -RLLGWMLASPTGPERIKAGVPAGWRVAHKTGTGGYGPTNDIGLIYPPSAPPVVVAAYFHA -TESTEAQRDAVIADATRMAL--- ->[subseq from] Beta-lactamase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=A0A318PZ94_KOMHA --------LSGYERATGGHVGVYAHNIVTGRKL-LWRADERFVMCSTFKASLVACVLSHVD -QGRDGLDRVIPLTGADIQDYAPVAKAALAQGMSVEDMCKGAVEQSDNSCATLLLSRIGGP -PALTAFWRAMGDGTTRLDDPEPFLNRTPAGGVRDTTTPAAMAGIMQGLVLGAVLSPSSRA -LLTRWLIGCQTGKNRLRAGLPANWVVGDKTGNNARDAAGDIAVAWPHPDMPIVMCVYTRG -GTPTEPQFANVFAGVGRFVAR-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE4EFC9 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004466297 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNNANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. JB110 TaxID=2024477 RepID=A0A368LDL2_9MICO -----DEELAPIEEEFHARVGVSVLDTGTGATI-DYRSEERFGFASTLKVFAVAEMLRQVA ---PEQRDELVTWTEETVADYSPITAEHVADGLTLAQLAEAALRDSDNAATNLILDRIGGV -EGMQAGLKRLGDSTTDVSDVEPELNEVVPGDTGNTTTPAAFTADLSALLRPEHLEPADRA -TLLEWMSGNATGDALIRAGAPADWAVADKSGGAG-AMRNDIAVVTAPGRDPIIVTILTEK -NDPDAAYEDEIVARVAEVVL--- ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000110964 -------ELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKNTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B170FB9 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Phormidium ambiguum IAM M-71 TaxID=454136 RepID=A0A1U7I927_9CYAN --nELRNQIEQISHTAQGQVGVTATVLETGETV-TLNGDRQFPMQSVYKFPIGMAVLAQVD -RGKLSLDRRVRVKASDFVSHSPIRDKYPQGVLSLAELLKYMVSESDGTACDVLLELVGGA -EVVTQYLRNLGVNGIVVANTEKEIGQDKAVQYRNYATPDAAVALLRALYEGKGLSKSSQA -LLLRLMTETPTGLRRIKGLLPDGTVVAHKTGTSRTAATNDVGLVTLRNGQHLAIAVFVSD -SKANDTIREQVIAKVARAAWDKw ->[subseq from] class A beta-lactamase n=1 Tax=Microlunatus speluncae TaxID=2594267 RepID=UPI0012662C96 ---AATDKITELERRHDITIGLYARNLETGATL-GHRTEERFPHCSVFKALAVATLLDDRR -HQRGILERGVHYAPKSLVDYSPFMQECLDRGPTGADVCKATLQLSDNGAGNWVLSVIDGP -AGATRFVRRLGDRVTRMDRWETELNSAVPGDPRDTSSPRAIADTFTRLIIGNALRPAERR -RLTTWMLGNQTSDDRFRAGLPEGWRLADKTGGGAYGVSNDVGIAWTDRNVPVVIAAFTRS -DREDAPTTDAVVAELARIS---- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WUY8_9BACT --nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIAMAVLAQVD -QGKLKLDRKIRVETSDVLQGSRILDEKSQGMFSLAELLKYMVSESDGTSCNVLLRQVGDP -RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRAFHEGKGLSKSSQA -LLLQLMTETTTGPQRIKGLLPDGTVVAHKTGTSSTAATNDVGLVTLPNGRHMAIAVFVSD -SGANNATREEVIAKVTKAAWDEw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WVB1_9BACT ---TLQKRIEEIAAGAQGKVGVAAVVLETGEAF-GFNENEHFPMQSVYKFPIAMAVLKQIE -QGNLKLEQNIRIEKSDLVPRSPIRDRFPQGTMTLNDILKYSVSDSDGTACDVLLKTIGGA -DAVTKYLRDTGVKDIVVATTERAMSQDESVQYQNWASPQATNDLLRLLHSGGVLAESNRA -LLLQWMTETPTSAKRIKGLLPAGTVVAHKTGTSNTRATNDVGLVTLPDGKHLAISVFVSD -SKADETTREEVIAKITRAIWDEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI00019291AB -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. PhB152 TaxID=2485190 RepID=UPI000F4B0E60 ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKAPAAAEFLRSVP ---ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -IALDRALEQLGDTTTDVVDDEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPAADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSR -NDPEAGYDDALVARAAAVVL--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium bisphenolivorans TaxID=1335760 RepID=UPI0003A110CF ---------KQIEAETGGRLGVALVDSRGALIL-GFNRDERFAMCSTFKAPLAAAVLTGAE -GGKFGLEGEISFGKADILEHAPAVKKNLKRGMSMDELAAAAVELSDNSAANLLLPMIGGP -EGLTRYIRAHGDTVTRLDRTEPSLNENAAGDERDTTSPAAMAGLMARLIFRD-LKPDSAA -KLRGWLNASSTGANRIKAGLPKGWTSGSKTGSCGT-AYNDVALVKAPSGEEYILAIYLDR -PRVDSKAAEAAIAETASAALD-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Bacillales TaxID=1385 RepID=UPI00046F34FA ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA73BFD ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKELGDKGTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingopyxis baekryungensis TaxID=279369 RepID=UPI0003B49E15 ---DLGAQMVAIETETGGRLGAFVVDADGKSLL-AYRADERFAMCSTFKTLLAAMVLEGVQ -QGSYDLDQPLAFDPADLVGYSPYVERYAAVGVTLGGAAGAAVSLSDNSAANLLYDLVGGP -GTLFQWLRTTGDKVSWPSRLEPDLNENAAGDMRDTTTPAAMGKTLHRLLTGNRLNNISKA -QLETWLRASETGGARIRAGLPARWVVGDKTGTCGNPAYNDVAVVRPSPREPYVIAVYLDR -PATDAAAADAAIAKVAALAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Flavobacterium sp. BBQ-18 TaxID=1932779 RepID=UPI0013771F62 --------LSDLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRAQ -AGQERLDRRIPITTADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLRRLFLNSALTAASRA -LLLQWMTDTPTGQNRLRAGTPAEWRVAHKTGTGGYGPTNDIGLLYPPDGQPVIVAAYYHA -TRATDDANAAVIAEATRRAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238UT07_9ACTN ---DLNTTLQELEKSYDGRIGAVGIDLGTGRTV-GYRADERFPFDSMFKVFACAAVMQKAR -TGEPLMDKVLHWKPADMAENSPETTEYTDTGMTPAQLCRAGVTKSDGFAGNTLLGQLGGP -RGLTRFLRATGDGTSRLDRPEPHLTEWKPGEDRDTTTPAAAARTFTKLTTGKTLHARDRA -RLLGWLKGSLTGANRIRAGLPKDWTVGDKTGTGGYGTANDIAIVWTPGSAPLVLSVFTNR -NR-QVPHDDKVIASTATALAK-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium faniae TaxID=570446 RepID=A0A1G4QWY0_9SPHN ---------KEIEEETGGRLGVALVDSSGALIL-GFNRDERFAMCSTFKAPLAAAVLLGAE -SGKFGLEGQVPFTKDDILPHAPVVKQNLKRGLSMAELAEAAVEVSDNSAANLLLPMIGGP -EGLTAFFRAHGDSFSRLDRKEPDLNENEEGDPRDTTSPAAMAELMTRLIFKDM-PPESAE -KLRGWLNGSKTGERRIKAGLPTGWTSGGKTGSCGT-AYNDVALVKSPSGAEYLLAVYLDR -PTVDEAKAEAAIAETAASALD-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium sp. YR708 TaxID=2135746 RepID=A0A4R2VAB7_9MYCO ------TRIAALEKRHNAFVGLYGQNLDSKVEV-AHRDGDLFAMCSTFKAYLSARVLQKAQ -AGELRLTDTVVVDPELLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGVLAVLAGTVLDEPHRR -QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPRGERLLLAIMTRT -QTANTPALRDLVGEVATVA---- ->[subseq from] class A beta-lactamase n=1 Tax=Mycobacterium sp. YR782 TaxID=2135747 RepID=UPI000D362531 ------TRIAALEKRHNAFVGLYGQNLDSKVEV-AHRDGDLFAMCSTFKAYLSARVLQKAQ -AGELRLTDTVVVDPELLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAANLLLRVIGGP -PAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGILAVLAGTVLDEPHRR -QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPRGERLLLAIMTRT -QTANTPALRDLVGEVATVA---- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002B95516 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. ysch24 TaxID=2683588 RepID=UPI0012F8558F ---AIRQKIGPITSTAQGHVGVALKLLETGDTL-SFGGNDRYPMQSVFKVPLAIAILDQVD -KGRLSLSQKITIRKEELRPWSPIRKKYPEGTMSLSDVLAYTVSQSDNNGCDILFRLLGGT -AYVNKYIHSLGIDSINIVATEEDMSKAWEVQYTDWSTPLAIVQLMEGIHKGSWLSKSSND -FLLKIMTETNTGPGRIKGLLPANAVVAHKTGTSDTAATNDAGIITLPGGKHLAIVVFVSD -ARAAEKTRDEVIAKIARLCWD-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B959D90 ----HAKELNNLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. KM4 TaxID=1628191 RepID=A0A0F3LFS6_9CAUL --------LSDLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRRIPITTADMINHAPVTEPAVGASLTVEQLLKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLRRLFLNSALTAASRA -LLLQWMTDTPTGQNRLRAGTPAEWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -TGTSDDANAAVIAEATRRAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E3D740C ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDNIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. B6 TaxID=1295626 RepID=UPI001237643A ------------------RLGVHALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- --GVDGMDERVPVEAADLVTYSPVTEQRVGVGMTWRELVDAALRFSDNTAGNLLLAGAGGP -AALTAWLRGLGDDVTRSDRTEPDLNAFVPGDERDTSTPGALAGTYRTLVLGDALGGPERD -LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTGAGAPVVLAVLSDR -ADPGAERTDAPVAEAARVVLD-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0006B4CE25 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDAAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura flavalba TaxID=1120938 RepID=UPI0003A4B65D ----LDRALRALEKSYDGRIGAVGIDLGTGRTV-GYRADERFPFNSVFKAFACAAVLHKAR -NGSPLMDRIVRWTPSEVAENSPETTEYTDTGMTPAQFCRAGITRSDGFAGNMMLRQIGGP -AGLTAFFRAQGDRTSRLDRPEPGLTEWSPGERRDTTSPAAAARTFSALTAGGALHPDDRA -RLVGWLKATVTGDKRIRAGLPKTWTVGDKTGTGGHGTANDLAIVWPPGAAPIILSIFTNR -TADNTPAEEKVIASTATALA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Lactobacillus gasseri 224-1 TaxID=679196 RepID=D1YJY8_LACGS ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSA----------------------------------------- ------------------------ ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A60EF7A ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKNGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Leaf363 TaxID=1736353 RepID=A0A0Q5V1Y8_9CAUL -------DLSGLERADGGRIGSAAHNTATGERL-HWRGDERFVYCSTFKMYLAAATLMRVQ -AGEERLDRRIPITRADMINHAPVTQPAVGAGLTVEQLMKGTVEVSDNPAANLLLKAMGGL -ETMQAFYRGLGDPSTRVDRFEPEMNRL--DGNKDTITPSQSVANMQRLFIDPALSAASKA -MLLGWMTTSPTGTDRLKGGVPAGWRVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA -TRDTDARNAAVIAAATRLALASf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000345FA42 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001232D366 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGP---------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Euryhalocaulis caribicus TaxID=1161401 RepID=UPI0003A63303 ---SLEHHLARIAGNLDGVVGVSIRDLSSGAAF-GLNADEAFPMASTFKIAVAGAILEQVD -SGELTLEQMVTVDPDMHVPSEIIADRFIHPGLSVANLMELMLTQSDNTATDVLTELAGGP -AAVTGWLASIGVEGQRVDRDTAGLLRAFYNDPKDTSTPDAMADLLTRIVQGEALGADSTE -FLVGVMERCRTGEGRLKGLLPEGVTVAHKTGTVG-GTVNDVGVMTLPGGRQVVIAVFVKA -SPAPAEARERTIAEIARTAYDYf ->[subseq from] Beta-lactamase class A n=2 Tax=Insolitispirillum peregrinum TaxID=80876 RepID=A0A1N7JH88_9PROT ----MEARLKKLEAQSGGRLGVAVLDSATGQVT-GNHLDERVAMCSTVKTLIVAYVLARVD -RQMETLDRRIVFTAHDLVSPYKATQPHVGPEMSIAALCEAAITVSDSTAANLLLTSFGGP -VALTSYLQSLGDEVTRSDRFELALNVVKPGEAHDTTTPRAMVGTLHRLLLDDALLETSRA -RLTNWMIEAKDATRRLRVGLPAGWRIANKPGTWEGISTNDVAVIWPPSRAPIVVATYLGN -APGSIIMQEGILADVARIIAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Kocuria halotolerans TaxID=405770 RepID=UPI00101E213F -------GLESLEAEFDARIGVSALDTGSGDVV-EHRADERFGYASSLKVLAAAELLQQVP ---ADQREERVTWTQEDVDAHSPVTSEHLDEGLTYPELAEAAVRQSDNTAMNLMLARIGGP -AGLDAALEELGDTTTEVVNEEPALNAVEPGGTDDTTSPSAFTADLDALFDPQVLDPADRE -TLIDWMSGNPTGDTLIRAGAPEDWAVAEKSGGAG-GIRNDVAIVTPPDRAPIVITVLTQR -NDPEAEYDDALVARAAEAVLGEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066C2243 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=20 Tax=Staphylococcaceae TaxID=90964 RepID=A0A3S7GZ77_STAHO ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066C5811 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001067BE7A ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138E205F ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Alishewanella jeotgali KCTC 22429 TaxID=1129374 RepID=H3ZHA0_9ALTE ----AAQRLQALEVG-HARLGVCLLDTATGEVS-GNRMDEYFAMCSTFKLALAAAYLREAD -QGRLDLDEMLPYSEADLLPWAPVTREHLAKGMTIIALLQAAQQFSDGVAANLMVKRLGGP -AMVTAKFREMGDNITRLDRYEPDLGLVLSADLRDTTTPRAMAQLVQRITCGELLQQDSRQ -RLLQWMESTNTGSKRLRAGLPATWRSGNKTGTGRTNKYNDIAITFPPGRSPIIIAAYFDS -GEQIEDRHQAVLADVGRIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces sp. CNT360 TaxID=1288080 RepID=UPI00041A2931 ------AAFARLERIHYAHLGLYAVDTGNGNQV-TWNDTRRFSYNSTVKSFLAAAVLKKNR --SDGDMDRVLHYDRSDLTANSPVSEKHVGTGMSRRALCDAAVRYSDNTAANVLFEDIGGP -GRLGTFLKTLHDTVTRTDRVEPHLSRWSPGEQHDTSTARQMASDLRELVLGRTLRTAERR -QLTTWLRTNTTGDTTIRAGVPKGWKVGDKTGTGSYAARDDIAVIWPPGRKPLVMAVLTYR -DGKNAEADDKLPADAAKAAIT-- ->[subseq from] Beta-lactamase n=1 Tax=Alishewanella sp. HH-ZS TaxID=1856684 RepID=A0A1C2BTT4_9ALTE -----AKRLQALEVG-HARLGVCLLDTATGEVS-GNRLDEYFAMCSTFKLALAAAYLREAD -QGRLDLDEMLPYSEADLLPWAPVTREHLAKGMTIIALLQAAQQFSDGVAANLLVKRLGGP -AMVTAKFREMGDNITRLDRYEPDLGLVLSADLRDTTTPRAMAQLVQRITCGELLQQDSRQ -RLLQWMESTNTGSKRLRAGLPATWRSGNKTGTGRTNKYNDIAITFPPGRSPIIIAAYFDS -GEQIEDRHQAVLADVGRIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium flaccumfaciens TaxID=2035 RepID=A0A4R6DHB4_9MICO ----IDRALAALETEYDATVGVVATDTATGESV-AYNGDRRFGYASTIKAFAAAQFLRSVQ ---GSDRDEVVHWTAADVAAHSPVTEQRVADGLSYAALAEAAVRQSDNTALNLVLTRIGGP -NALDSALHDLGDDVTQVVHDEPDLNTIEPGSTEDTTTPAALAADLATLFDGTTLDAADRA -QLLDWMGGNATGDTLVRAGAPTGWTVADKSGGAG-GIRNDIALVTRPGGAPIVIAVLTAK -NDPAAAYDDTLVAKTASTVLGAf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2H1KY28_9MICO ---EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT ---PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP -KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT -VLIDWMSDNETGDPLIRAGAPAGWKVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN -NDPNTESDAALIEDIAHAVLGAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012EE3504 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVKYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Rhizomicrobium sp. SCGC AG-212-E05 TaxID=1799655 RepID=A0A177Q804_9PROT -------AIAAIERKHGGRLGVFALDTATRKTM-SWRADERFTMCSTFKLLLAAQVLAKVD -AGTENPNRKLFYGPGDLIFGSPVTTRHVDERLSIAVLTRAIVETSDNTAAILLMRAMGGP -ESLTRFVRSLDDEATRMDRYEPDANLY--DPLLDTTTPRAIILTLRRILMGKVLSPRSGQ -LLEGWMIASTTGTERLRAAFPRRWIAGDKTGTSAERQTNDIAFLRPPGRRPLLIAAYYDA -PRVSLAEREQVMRETGEAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis subsp. tessellarius TaxID=31965 RepID=A0A225C7W9_9MICO ---AADAAFAALEERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMERAVPIEAADVLAYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLMFRALGGP -SELDAALTALGDDTTVVARDEPTLNEATPGDDRDTTTPRATAALLRAYALGDALDDDERA -LFTGWLKATQTGATLVRAELPTEWTVGDKSGSGAYASRGDVAVIWRPDAAP--IAAHSSK -DRQDAVADDALISGAAKAAAQ-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0002506AF6 ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00066A6F10 ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. Ae356_Ps1 TaxID=1885032 RepID=A0A1Q8JTS2_9PSEU ---------DGVEREFGRRIGVHVLDTGTGTTA-GHRDGERFLMCSVVKALMAGFVLHRSV -ADPALLDRPVRWGRADLLEYAPVTFRHVDSGLSVAQLCEAAVTVSDNTAHNLLLREVGSP -ADLTAWLRSTGDGVTRADRYETALNDV--DGDRDTSTPAALAATLRALTTGDVLPSAQRD -RLVGWLRANTTGDEQIRAGVPDGWQVGDKTGSGPLGEKNDAGVLFPPQGAPVLLTVFTVP -ADPDDDRGAAAVASATRAA---- ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium naphthalenivorans TaxID=273168 RepID=UPI0008328B6C -----TDALRAIERDAGGRLGVFVHDTASGRSF-GWRQNERFTHCSSFKLSLAAMMFAGRD -AGTIDLGRVLHWTQADLLPHSPTTTPHVGSGLTVNELARAALIESDNTAANVLLKTFGGP -EAVTRFWRTLGDRVSRLDRFEPDLNITPPGTELDTTTPKAMAGTLQTLLTGQHLSVQSRE -TLKTWMSAVTTGSDRLRAGFPKSWASGDKTGTGRY-TYVDLAFGGPAGKPPLYVAAYFEP -AVHRDPAATAVLAAVGDVAARHy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00124E5FF9 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000807659E ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKNDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Mycolicibacterium sarraceniae TaxID=1534348 RepID=UPI00138BFA96 ------TRIEALEKRHNAFVGLYGQNLDSKVEV-AHRDGDLFAMCSTFKGYLSARVLQKAQ -AGELRLTDTVLVDTELLRPNSPRTEPNVGKPMALSELCAAALQVSDNTAANLLLRVIGGP -PAITTFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGILTVLTGDVLDPPHRK -QLEDWMRANTT--SSMRAGLPPGWTTADKTGSGDFASTNDVGIAFGPGGERLLLAIMTRT -QSANTPALRDLVGEVATVAV--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00076973AD ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=7 Tax=Staphylococcus TaxID=1279 RepID=A0A4Q9WNF3_STAHO ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044A9D50 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012AFAFAA ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIETSMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Paenibacillus polymyxa TaxID=1406 RepID=UPI000578158D ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A177K1A4_SPHYA ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007696180 -----AKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. IP1 TaxID=2021637 RepID=A0A2G1LIY6_9SPHN ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SFD4_9BACT ---DLRGQIEQIAREAKGRVGAAVLIVETGETV-AVHGDEQFPMQSVYKLPIGMATLREVE -RGRLKLEQQVRVEKSDLVSHSPIRDKYPQGGLTVRECLRAMLVESDGTASDILLRLAGGP -RRVTDYLRGLGVTEIVVATSEQEMAQGEMVQYQNWATPEAMAGLLRALQQGRGLAAGSRA -LLLQFMTETTTFPHRLKGRLPAGTVVAHKTGSSGTAATNDVGVITLPNGRHLLVVVFVSD -STADDATRDDVIAKIARAAYD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3YQ02_9MICO ---EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT ---PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP -KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT -VLIDWMSDNETGDPLIRAGAPAGWTVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN -NDPNTESDAALIEDIAHAVLGAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009168039 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELEDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A430BHK4_SPHYA ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDMASA-DAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAQAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Leaf168 TaxID=1736283 RepID=A0A0Q5MWH3_9CAUL --------LADLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKLYLAAATLLRVQ -AGQERLDRRIPIAAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLERLFLDPTLTAASRA -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -ARATDDANAAVIAEATRRALK-- ->[subseq from] Beta-lactamase n=1 Tax=Vibrio caribbeanicus ATCC BAA-2122 TaxID=796620 RepID=E3BL73_9VIBR --kDLTTTLSELEQKIEGQIGVAVIDTQFSTEW-SYHGDDRFPMMSTFKTLACANVLYDVE -KNKLNMSQKITVTKAGLINWNPITQHFVGGNMSLKSVCGATMLMSDNYAANLALEQVGGP -EGVTQFLRSIGDKATRLDHYEPKLNYVEKNAINDTTTPLAMLRTLQKLLLGNVLNSESKE -QLKFWMTNNMVSDGLARSVLPENWAIADRSGGGVNNSRTLTAMIWSKERKPIFIGIFIAN -SKSELSELNKVVANISHEIFTKy ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=A0A4Q5KKQ4_9GAMM ----TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS -NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP -TSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN -TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAVLWNEKRAPIIISIYLTQ -TNLDMAARNQVIVEVGNAIFKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0008D9D9B1 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -TKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Plantibacter sp. T3 TaxID=2653161 RepID=A0A653P6B8_9MICO -------EFQALEAEFSARVGVSAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR ---GSARDEVVTWSAEDVEEYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP -AALDAALVALGDEVTEVVNAEPLLNVIEPGSTDDTTSPAAFTDNLTRLVDGSYLESADRA -TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GMRNDIAIIDRPGGDPIVLTILTNT -LDPDAEYDDALVAEAARVALAAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00071DDF29 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDALIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Uncharacterized protein (Fragment) n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1R6W8_9ZZZZ ------------------------------------------------------------- -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGVGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VE47_9MICO -----TAALQDLEQQFGARVGVSAVDTGTGEQL-SYRADERFGYASTLKVFAAAAFLHDVP ---ASERQTVVTFTADDVEAYSPVTAENIETGLTLSQLAEAAVRRSDNTALNLILERLGGP -AALDATLSSLGDDTSEVVNSEPALNAIEPGSTEDTSTPAAFTADLSRLIDGSYLAPDDRT -ILLDWMTGNTTGDTLIRAGAPSGWSVADKSGGAG-GIRNDIAVVTPPGGHLIVVTIFTNT -LDPEAAYDDALVVGVARAVL--- ->[subseq from] Beta-lactamase n=12 Tax=Staphylococcus TaxID=1279 RepID=T1YC08_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00066E76D2 ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKNDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae ATCC 51230 TaxID=883163 RepID=K9CXK9_SPHYA ---------KEIEEETGGRMGIALVDREGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase class A n=3 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A2U1G8F3_9PSED -----DDDFAKVERESGGKLGVYVLDTGSNAHF-GWREDSRFPFCSSFKAPLAAFVLWLSD -QGRLALDQVVRYGEPDLLPYAPTTRANVKNGMTIDALCAAAVLLSDNTAANLLLRETGGP -QALTEWMRWQGDSDFQLSDNEPKLNLSRFADAANTTTAKAMAGSFSRFLSGPLLTPASQA -RFKDWILANQTGAKRLRAGLPAAWQVGDKTGTFNEGSTVDIAAAWPGARKPIIISAFSTD -TP-DTQSGERALAAIARLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. PAMC28499 TaxID=2565554 RepID=A0A4P7QPD3_9SPHN ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPDLNENVAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=A0A2S6DXH3_STAHA ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADRSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB118 TaxID=2485175 RepID=A0A3N2HXV4_9MICO ---EVEAALADLETRYDARIGLSVLDTGSGATL-DHRADERFGYASSLKAFAAAALLEATD ---DADLDRVVTWTQAEVDAYSPLTSTHVADGLPLRQLAEAAVRKSDNTALNLVLAELGGP -AGLDAALAAQGDGVTDVVHGEPELNRLTPGSTADTTTPAAFTATLARISDGDWLAADDRA -TLLEWMSGNATGDTLIRAGAPDDWQVADKSGGAG-GIRNDVAIVVPPSGDPVVISVLTTR -NDPAASYDDALVAAAAEVAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=UPI00031E6BFA ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKNKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2803 TaxID=2609256 RepID=UPI00135CEE5E ----VSAELAALESEFDARIGVSAVDTASDRRV-SHRQDERFGYASSIKALAAAQFLRAVP ---AAERDEIVTWTASDVEAYSPVTSESIGDGLPLSELVEAAVRESDNTALNLVLARLGGP -AALDRGLEELGDTTTEVVDEEPALNTIEPGGTANTTTPSAFTAALGAVALGSALPPEDRA -LLLDWMSGNATGDALIRAGAPSGWGVADKSGGAG-GIRNDVAVVTPPEREPIVITVLTER -NDRDADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. YZ-8 TaxID=2319844 RepID=UPI0013CEC704 ------PQFAALEKASGGRLGVSVFDTRTGSIT-GHRAAERFTMCSTFKLPLVAAVFAAAD -AGAIDLNRKLSFAASDLPGNSPVTRANLARGMSIVDLAEAAQSVSDNGAANLLLKHIGGP -AALTAFFREAGDPTSRLDHYEPELNYSHGTDIRDTTTPAAMAVLLSGIFTGSLLKPASRD -RLIAWTIATKTGTHRIRAGLPSDWRAGDKTGTMTASKYNDVAIVWRRETTPFVVSVFYEA -PVDAVSVQEAVIAQAGKLAAE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007697B1C ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYTSRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044CCF21 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=3 Tax=Terrabacteria group TaxID=1783272 RepID=A0A507SR92_9STAP ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=6 Tax=Staphylococcus aureus TaxID=1280 RepID=M5APG0_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSSILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase class A n=1 Tax=Rathayibacter sp. PhB179 TaxID=2485197 RepID=A0A4R1VDM7_9MICO ----VSAELAALETEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---VGERDEDVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -AALDRALEQLGDTTTDVVDEEPALNTIAPGSTANTTTPAAFTADLTAVALGEALPSADRA -LLLAWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDIAVVTPPGRDPIVLSVLTSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Hydrocarboniphaga daqingensis TaxID=490188 RepID=A0A1M5ND10_9GAMM ----ATAALQQLQQRSGGHIGVQVIDGTTGRRF-GLNTEQRFAMCSTFKLPLAALVLREAE -TAGLRLDTVLRYTRDDLVPHTPVTGAHLADGMRIVDLAEAAQVTSDNLAANLLIAALGGP -AAVTARFRAIGDEVMRLDRIEPELNRVPPGDLRDTTTPDAMARTVLRLFSSPVLGAVSQQ -WLRQWMQATQTGAARLRAGLPSHWAVGDKTGTALAHQHHDVAVIWRAAAAPVVIAAYYEA -PVADRAADDAVLAEVGRIVA--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000F8A1D02 -----AKKLNDLEKKYNGHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00091DB3E1 ----HAKELNNLEKKYNANIGVYALDTKNGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DE17FA6 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKAKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00069FEFB0 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPNNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A3G2UN47_SPHYA ---------KEIEEETGGRMGIALVDREGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPDLNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia harenae TaxID=358707 RepID=UPI00082BF5B9 ----LDSALAAIQDRHSVRVALYARY--RDRTV-AHRASEPIAMCSTFKAYAAAAILRLES -EGALRLDETVPVRPADIVVNSPITEAAQGTDLSYAQLCAAALTRSDNTAGNLLLRRIGGP -AALTAFARTLGDRATRLERWEPDLNLAERDTLADTTTADGLATGYAALLLGTALPPAQRR -TLTDWMAASTTSARRIRAALPPGWTAADKTGGGNYGTVNDAGVLWSPDGTPLLLVLLTDS -TTGDVTPADAALAEATTAVL--- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Brevundimonas sp. Bb-A TaxID=2560058 RepID=A0A5P9KRN8_9CAUL --------LNDLETRWGGRLGVAALDVGSGVRA-LWRSQERFPFCSTFKPFLAAAILQRVQ -RDEERLDRPVRITSADIIPHAPVTEKAVGRTLTIRELMQAAVEVSDNPAANILIREMGGI -GVWRSWWPTFGDTTTVISRLEPDLNTALPDDPRDTCLPEQTVANIREMAFSDRLTPAHDA -LLHGWLTASPTGPNRIKAGAPEGWSVAHKTGSGARGTTNDVGMLTPLSGSPVIIAAYFTG -AAATEDQRDAVIAEATRRALK-- ->[subseq from] CARB/PSE/RTG family carbenicillin-hydrolyzing class A beta-lactamase n=1 Tax=Vibrio sp. (strain EJY3) TaxID=1116375 RepID=UPI000243B683 ---KLHEDVSLLEQQISGRIGIAVWDTQTDKHW-AYRGDERFPLVGTFKTLACATMLSEMD -TGILKKNATAIVEKRDMVMWSPIMDKLAGQNVRIEHACEAAMLMNDNTATNLVLSEIGGP -KSVMLFLRTIGDKATRLDSAEPSVNEAMPGDKHDTTTPNAMVNTLETLIDGDALSYESRI -QLKIWMQDSKVSDPLMRSVLPSGWSIADRSGAGGNGSLGFNAIIWKENHKPVYISIYLAE -TELSLQAREQLIAQISQLILYKy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=UPI000D1E8561 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000451FD27 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNIINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000493EF21 ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVISKf ->[subseq from] Beta-lactamase n=22 Tax=Bacteria TaxID=2 RepID=D2JEK2_STAAU ----HAKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI00069DB509 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPISEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013A6D267 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVVFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2760 TaxID=2609253 RepID=UPI0013194C65 ----VSAALGALEAEFDARIGVSALDTGSGTRV-AHRADERFGYASSIKALAAAQFLRSVP ---AAERGEVVTWTAADVEAYSPVTSESIENGLPLDRLAEAAVRRSDNTALNLVLDRLGGP -AALDRGLEELGDTVTRVVNEEPALNTIEPGSTDDTTTPAAVTADLAAVTLGDALSAADRA -LLLDWMSGNATGDQLIRAGAPEGWTVADKSGGAG-GIRTDIAVVTPPGRAPIVLSVLTAR -NDPDATYDDALVARAAAAVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter festucae DSM 15932 TaxID=1328866 RepID=A0A3Q9URS7_9MICO ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LYRQDERFGYASSIKALAAAEFLRSVP ---ADERDEIVTWTAADVEAYSPVTSESIDGGLSLAQLAEAAVRRSDNTALNLVLDRLGGP -AALDRALEQLGDTTTDVVDEEPALNSIALGSTANTTTPAAFTADLAAVALGEALPSADRA -LLLDWMSGNATGDALIRAGAPQGWTVADKSGGAG-GLRNDVAVVTPPGRDPIVLSVLTSS -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B953FF4 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Microcoleus vaginatus FGP-2 TaxID=756067 RepID=F5UQ44_9CYAN --------------------------------V-TLKGNQQFPMQSVYKFPIAMAVLAQVD -QGKLKLHQKIRVETSDVLQGSRILDEKSQGMFILAELLKYMVSESDGTSCNVLLRQVGEP -RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRALHEGKGLSKSSQA -LLLQLMTQTTTGPKRIKGLLRDGTVVAHKTGTSSTAATNDVGLVALPNGQHMALAVFVSD -SPANDAIREEVIAKVTKVAWDEw ->[subseq from] Beta-lactamase n=3 Tax=Staphylococcus TaxID=1279 RepID=A0A317YTV6_STAPS ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI00135883B8 ---IFRQEIDKIITASKSDVGVAIMSLEDKETF-LFNEGHKYPMQSVYKFPLAMAVLDQVD -KGKLSLNQKIHVTKKDLLPWSPLREKYPNGEIKVSELIGYAVANSDNNACDLLFRLVGGP -KKVDQYIHSLGIKSIAIATTEEEMSKAWNVQFKNWCKPRAMLRLLDLFYKGKNLSKASTN -FLMKTMTETTTGPNKIKGLLPKNTKVAHKTGMSGTAASNDVGIITLPNGEHVAVVIFLAH -TKLDEKSRDAVMAKISKQAYDYf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044F47DE ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIDASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD2E5C5 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKLTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella sp. TaxID=576 RepID=A0A2P1MSM1_KLESP -----------------------------------------------SKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVLIFS- ------------------------ ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112162 ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELQYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] ARL family class A beta-lactamase n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=UPI000DCC1856 -----AQGLTKLEHKNDATVGVYGINTATGQTY-SHNADTRFAYASTFKAITSGLLLQQNS ---PEALNKTVTIKESDIVAYSPVTEQYVGKTMTLRQLISAAMLQSDNTASNIITEQLGGL -DQISSRLQALGDTTTNSQRYEPELNNYDPQSTADTSTPRATAHNLQKLLTTDAVAPQQRK -FLQNLMFNNKTGESLIKKGVPNSYKVGDKSGQGTYGTRNDVAVIYPKHQKPIILVVFTKH -QQQDAQPQDELVAQAARHAIH-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002F8E3C7 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTLKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis lindanitolerans TaxID=2054227 RepID=A0A2S8B442_9SPHN ---ALARTLTAIERRWGGRLGVAVTDTTGRLLF-GQRADERFAMCSTFKLLLAGQVLHDAA -NGGLALDTSLPLVETDLLPHSPYSETQLAAGLRLGSAAEHSVKISDNAAANLILKATGGP -PGFTRHMRAMGDAVTRLDRTEPDLNENVPGDPRDTTSPAAMAKSGATLVYGDYLDADGRR -TLRSWLVGSTTGRARLRGGLPPAWIAGDKTGSCGT-AYNDVAFVEAPDGGRYMVAAYLDR -PTVNGDAADAILAEVGRAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Georgenia sp. ZLJ0423 TaxID=2483799 RepID=UPI000F08E1D2 ---DITADLDALETEFDARVGVSALDTETGRSV-EYRAEERFGYASTLKVFAAAELLREVP ---PEEREARVVWTQEEVDAYSPVTSEHLDGGLTVAELAEAAVRESDNTAMNLVLDRIGGP -AGLDAGLAALGDETTDVVSNEPSLNEVDAGGTRDTTTPAAFTAALDALLQPRNLAPDDLA -TLLDWMSGNATGDALIRAGAPADWVVRDKSGGAG-GIRNDIALVTPPGRAPIVVTVLTEK -NDRAAEYDDELVARVAEVVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. GV013 TaxID=2135688 RepID=A0A4R7DJW1_9SPHN -----SARLAAIERRGGGRLGAYVLDTGSGRGF-GWRAAERFAMCSTFKLSLAAWLLREID -AGRIAGDEMLGFGRGDLLPNSPVTGARVATGMTVLDLAEAAQKTSDNLAANLLMRRLGGP -AGLTAFWRSLGDRTSRLDRYETDLNFVPRGDRRDTTTAAAITATAARFLTGPLLTPASRK -LLLRWMAETTTGAHRLRAGLPAGWRGGDKTGTGMPTKLNDIAILYPPAGSPLVVTAFYEP -AGDPLPAHEAVLAQVGALAT--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E011143 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRFKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A326KX59_9CAUL -----DLHLSDLEGRHGGRLGVAALDVASGRQA-LWRAQERFPFCSTFKAFLAAATLQRVQ -RGEEDLERRVRVTRADMIPHAPTTGPAVGRDLSIRQLMQAAVELSDNPAANILIREMGGI -GVWRQWWPSFGDTTTLISRLEPELNTALADDPRDTCLPAQTLANIRLMAFSDRLSPAHDA -LLHDWLVASPTGPNRLKAAAPQGWTVAHKTGTGMNGTANDIGMMTPVSGAPVLMAVYLTG -ATATDDQRDAVIADAGRRAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004501CAD ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Yersinia intermedia TaxID=631 RepID=UPI0005E46BD2 ---SLDNQLAELEKSSNGRLGLALINTGKGTKI-HYRGGQRFPFCSTFKLMLAAAVLGRSQ -SQPNLLSKHITYHESDLLAYAPITRKHLAQGMTVAELCAATIQYSDNTAANLLIKQLGGL -AMVNQFARSIGDQTFRLDRWEPELNTALPNDPRDTTTPAAMAASVNKLVLGDALAAPQRE -QLALWLKGNTTGAATIRAGAP--------------------------------------- ------------------------ ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000768EB39 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKHLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D1CD33A ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKKGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0004470F0D ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELRDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002506D50 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSKPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522QWW8_9BACT --sSLQQKIAHICQSKHAVVGVAIMNLETGDTL-TYNGEKHFPMQSVFKLPLALAILSKVD -NGIFSLDQSVFISKNDLLPWSPLREKYPDGNLPLSELLQYTVAQSDNNGCDILFGLIGGT -GKVNTCIRQLRIKNIVIAATEVEMHKEWNVQFSNWATPYAMVKLLDIFYKGHILSPKSRK -FLLKTMENTVTGTDKIKGLLPPGTIVAHKTGSSDRNADNDAGIVTLPNGRHFAIVVFITH -STESDKTNARTIAEISRVVWDYf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005DC5A34 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Listeria grandensis TaxID=1494963 RepID=UPI00098CFB13 ------------------------MDTASNKTI-GYNDQERFAYCSSFKAIAGGILLKNLT ---LEQLNKRIHFKKEDLIDHSPITEKHTEDGMTLKEIINAAMTYSDNTAANLMLHELGGP -KAYQKELVKIGDTVTQSDRYEPELNSAVPGDKRDTTTPEAMAKNLAFLVKKGNMPTDNFN -YFKQTLIDNTTGDKLIRAGVPEGYIVGDKTGSGSYGTRNDIAVIYPKDKKPLVWVIYSKK -DTEDAEYDDQLIADAAKVLSKYf ->[subseq from] class A beta-lactamase n=1 Tax=Carnobacterium divergens TaxID=2748 RepID=UPI001072CA79 -------NFEKLEKKYEATLGVYGLDTETNKVV-AYNENQRFSFASTYKALAGGLVLNESS ---WDELNQTIMIKKEDLVTYSPITEKYVDIGIPLKELISAAIQYSDNTAGNFLFKQLGGP -KGFQTKLAELGDYTTDSSRFETELNEATPGDIRDTSTPKEIALDLKKVAIDHKLPTDKLE -FYKKQLIENTTGSKLIRAGVPSDVIVGDKSGAGSYGTRNDIAVLYPPNRKPIVLVIFSNK -EQQESDYNDALISETAKIVSNDf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A5C8X378_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=D2JD74_STAAU -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Asticcacaulis sp. CF398 TaxID=2135738 RepID=A0A2T5XKH5_9CAUL ---SLAEWCAELEVQTKQRIGVYVISSDTVEEE-GHRWDEPFAMCSTFKWVLAAAVLKFVT -DGALRLDQSVPFSEVDILEHAPVVRKNLPKGLTVSELCAAAVSVSDNSAANLLLPLVGGP -AGLTHFVRSLGDNVTRFDRIEPALNTNEAGDPRDTTTPKAMARLLHKVFFGDVLPPASVS -LLKQWMVDATTGRDLIRSGVPKTWKVGDKTGRGANGALNDVAIVWSASGVFDLVCVYTTG -GQLTDPERRQVLARIGRYA---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009BF4199 ------SPLAEIERRNGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYSENDLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRV -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLFVAIYYDA -PGVSLDAREAVLREAGSAFV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UI95_KLEPN ------------------------INTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLADLSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLTTAIPGDPRDTTSPRAMAQILRNLTLGKALGDSQRA -QLVTWMKGNTPGAASIQAGLPASWVGGDKTGSGGYGPTNDIPGICPKDRAPL-------- ------------------------ ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00080B5E3D ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001068BA96 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKFISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A351CXV7_9GAMM ----LMTKVKAIENQLDARIGVSIYDATHNQHW-HYNGDTRFPLMSTFKTFACAKLLVDVE -CGLQSLDTSSVITTNAIITWSPITEKLVGERISLKQACAAAMTMSDNTAANIVLTGIKGP -KALTQFMRSIGDDVTRI---EPGLNEALNGDKRDTTTPNAIVKSLHLLLFGNVVSENSKA -LLKQWMIDNKVADSLLRSVLPKSWSIADRSGAGGSGSRGITAMVWSAERPPLMISIYITQ -TGAPLALRDKAIADIGEAIFNLy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066EC614 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGFPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138DD222 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLTKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2801 TaxID=2609255 RepID=UPI0013203677 ----VSADLAALEREFDARIGVSAVDTGSGRRV-EHRADERFGYASSLKALAAAEFLRTVP ---AAERDDVVTWTAADIEAYSPVTEASTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012908D08 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFDKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC073C02 TaxID=1739360 RepID=UPI0008A62F34 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI001374BA6A ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDRPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0J9D038_SPHYA ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium sp. LF-16 TaxID=2185111 RepID=UPI000F091F18 ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. YZ-8 TaxID=2319844 RepID=A0A494TMV4_9SPHN ------PQFAALEKASGGRLGVSVFDTRTGSIT-GHRAAERFTMCSTFKLPLVAAVFAAAD -AGAIDLNRKLSFAASDLPGNSPVTRANLARGMSIVDLAEAAQSVSDNGAANLLLKHIGGP -AALTAFFREAGDPTSRLDHYEPELNYSHGTDIRDTTTPAAMAVLLSGIFTGSLLKPASRD -RLIAWTIATKTGTHRIRAGLPSDWRAGDKTGTMTASKYNDVAIVWRRETTPFVVSVFYEA -PVDAVSVQEAVIAQAGKLAAE-- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI00131F4AB6 ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAVAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAEAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase class A n=2 Tax=Chryseolinea serpens TaxID=947013 RepID=A0A1M5TPR8_9BACT ---RLRGEMARITGSLSANVGVAVLNLDTGDTL-TWRGHNRFPMQSVFKFPLAIMVLHEID -RGALTLDQKIHLRKEDMMLWSPMATKYPEGNLALSEILRYTVSQSDNSGCDVLFRLMGGP -RKVNDFLHGLGITQIAIAATETEMHASWPVQFTNWCEPAAMTALLKQFDRGKILSPSSRE -FLWKLMVETSTGPKRIKGLLPEGTVVAHKTGTGDLGAFNDVGIVVLPDGSHVAIVVYISG -TKKDAAKLDLVIAQISRAVYDQy ->[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI0009BE827B ----------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIGDYAPFAKAHLDKGMSVAELCQEAIEQSDNFCANKLLERSGGV -LALTAFWRQLGDNQSQLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD -RLTGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG -GTPTKDQLLSLFSKIAH------ ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044A83D9 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSEKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=A0A2Z6TBQ6_BURVI ------SPLAEIERRSGGRLGVFAIDTGPGRTP-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTEKDLIFTSPVTKANVAQGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALARFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRA -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLLVAVYYDA -PGVSMDAREAVLREAGAAFVQ-- ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus epidermidis TaxID=1282 RepID=A0A659CEW2_STAEP ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002C9C928 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00026BF532 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000D743258 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKIKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. S-NIH.Pt3_0716 TaxID=1920124 RepID=A0A430D695_9SPHN ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDIALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=35 Tax=Bacillales TaxID=1385 RepID=D2J7V8_STAAU -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044DEC22 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C7 TaxID=2080540 RepID=UPI000CE86DE7 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKVLAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000452D05E -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQAKYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] UPI0012F4779E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012F4779E --nNTRQKVNEIAATARGHVGVAMMSLENGDTM-TLNGNDHFPMQSVFKVPLAIAVLDQVD -KGKLSLDQVIHITKKELLPWSPIREKYPEGTLKLREVLAYTVSQSDNNGCDILFNLVGGT -AYVEQYIHGLGVDSMAIKANEERMASAWKVQYTNWSSPLATLQLLKGIHTGKYLSKASND -FLLKIMKETTTGPKRLRGMLPADAVVAHKTGSSDTAATNDAGIVTLPDGSHLAIVVFVSD -TKVNEAIREGVIARITRLFWD-- ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0008468D2B ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPDLNENVAGDPRDTTSPAAMAGLMGRLLFRDM-QAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=A0A4Q5KQK1_9GAMM ----TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS -NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP -TSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN -TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAVLWNEKRAPIIMSIYLTQ -TNLDMAARNQVIVEVGNAIFKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012AFF105 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=54 Tax=Staphylococcus aureus TaxID=1280 RepID=Q60250_STAAU -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002CCA91D -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=V9SHK8_STAAU -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Paraburkholderia bannensis TaxID=765414 RepID=A0A658LAD8_9BURK ----ADSPLSDIERRHGGRLGVFAIDTGSCRTL-SHRAEERFLMCSTFKGLLAAQILARVD -GGAERLDRLVHYTEKDLIFTSPVTKANVAGGLSIDALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTITRSDRYEPESNRY--RGVLDTTTPKAIATTAQRLLLGDALSASSRA -QLERGMADCKPGLNRIRAVLPAGWQAADRPGTSVESETNDYALVRPPGRAPLLVAAYYDA -PGVSMEAREAVLREAGTAFV--- ->[subseq from] Beta-lactamase n=48 Tax=cellular organisms TaxID=131567 RepID=A0A0Y2CSL2_STREE ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium faeni TaxID=145483 RepID=UPI00141BC253 ---AVAADLAALEAEYDARVGVSVVDTGTGATL-SHRADERFGYASSLKALAAAQFLHDVP ---ADQRDEVVTWTAADVEAYSPVTSEHVADGLPLVQLAEAAVRRSDNTALNLVLARIGGP -AGLDAGLAAIEDRTTEVVGTEPDLNTIEPGSTDDTSTPTAFTADLVALLDGRWLADDDRA -LLLDWMSGNATGDTLIRAGAPSGWVVADKSGGAG-GIRNDVAVVTPPGRAPVVVSVFTSR -NDPDADYDDALVARTAALVL--- ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=3 Tax=Staphylococcus TaxID=1279 RepID=A0A6B5MC16_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -TKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138DD742 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Pseudarthrobacter sulfonivorans TaxID=121292 RepID=A0A0U3P9C4_9MICC ----LTRRMEVLEREFSARVGLFAVDGPTGAKF-GHRADERFAMCSTFKVYAAAAVLQRAS -EGLADLSRGIRIDPADVVVNSLECADFAGSTLPLKWFCKVALTHSDNSAGNQLLRELGGP -AAIGTYARSLGDTESRLDRWEPELNNAERGDPRDTSTPRALAHGYRKLLLGDALSPLVQA -QMTGWMLANGTSGQRMWAGLPDGWTSADKTGAGLFGTVNDVGVVRNPAGEPLVLSILTDT -ASADTPGSNELVAAITRAVT--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=D2JBV1_STAAU -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia sp. F TaxID=795955 RepID=UPI000255C8A3 ------AAVEQLEQEYDARVGVSMIDLGDGSTL-THRSDERFGFASTMKAFAAAALLHSTS ---AEERRQRVQWTSADLDAYSPVTEQAVETGLTLGELAEAAVRESDNTAMNLILEHLGGP -EGLQRSLEGLGDSVSRPVDVEPELNEIIPGDAANTSTAGALAGNLERLVDGDWLDEDDRR -VFMEWMSGNPTGDTLIRAGAPEDWSVAEKSGGAG-AIRNDAAVLQPPEGAPIVLVVLTER -NDADDEYEDALVAEVAGAVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=UPI00066C5419 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKTNKN -FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=UPI00101EAE15 ----TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS -NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP -TSLTLFLRLIGDDITRLDRIEPDLNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN -TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAILWNEKRAPIIMSIYLTQ -TNLDMASRNQVIVEVGNAIFKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000E0530A9 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKNDKPNDKLISETAKSVMKEf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR10 TaxID=2035405 RepID=A0A2H5W2M9_9BACT ---RLEREIARLAGIAGGVVGVAALHLESGRRV-ALNGAERFPMASTYKVPIAVQVLTKVD -HGELTLDQMITLEPADLSPGSGTLSDLFRAPLSVRNLLELMLLISDNTATDVLLRVAGGA -EAVTARLRELGIEGVRVDRPTKQVIARFDEDPRDTATPEAMVALLEQIYRGRALKRETTE -LLLDILQRCRTGEARLKGLLPPGTEVAHKTGTIG-GTTNDVGILTLPGDGHVAIAVFVKS -SDKDIPTRERAIAEIARAVHDFf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB25 TaxID=2485205 RepID=A0A4R8C001_9MICO --eRVRRALAGLERQYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000344EF30 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A6B9HRU2_STAEP ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRFKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVISKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA6CEB ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIPNGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=9 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0002CB0DE9 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007CA7451 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFIYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A084EFL3_SPHYA ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDMASA-DAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDRKAEAAIAEAAHSAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A33BBCC -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0W7D4_9MICO -----TAALAALEQQFGARVGVSAIDTVTGEQL-SFRADERFGYASTLKVFAAAAFLHDVP ---ASERQTVVTYTAADVEAYSPVTSESIGTGLTLSQLAEAAVRRSDNTAMNLILNRLGGP -AALDAALREQGDDVSEVVNSEPALNVIEPSSTDDTSTPAAFTANLSRLIDGPYLATDDRA -ILLEWMTGNTTGDTLIRAGAPSGWNVADKSGGAGS-IRNDIAVVTPPGGHPIVVTIFTNT -LDPDAAYDDALVTGVARAVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E0D0565 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNANKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0007C474B1 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYIGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium sp. ARR65 TaxID=1040989 RepID=UPI0004657AD0 -----EASIAEIEKRHGGRLGVFAVDTGTGRTL-AHRADERFLMCSTFKGLLAALVLARVD -AGQEALSRMIPYGEKDLIFTSPITKANVGKGLSVGDLTKALLEASDNTAAILLMRSAGGP -SGLTKFVRGLGDTVTRSDRYEPKSNED--SGILDTTTPRAIVGSVRKILLDNVLKPQSRQ -RLEAGMIACTPGLKRIRAALPSDWIAGDRPGTSTKGESNDYAIVRPPGRAPLLIAAYYNA -PKLSMAEREVVLRETGSAFV--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=UPI000A0FE521 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C2 TaxID=2080535 RepID=UPI000CE85CFF ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADQRFGFASSLKVLAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEKTTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00069F7719 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA745DA ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPLLEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066B9C67 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=A0A0H2VHE7_STAES ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQAP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase class A n=1 Tax=Frigoribacterium sp. PhB160 TaxID=2485192 RepID=A0A3N2ID41_9MICO ---RVDAALAALEAEFDARVGVSAVDTGDGRSI-GHRADERFLYASSLKALAAAALLDVTT ---ADDLAERATWTSADVAAYSPVTELHVVGGLSYAELAEAAVRKSDNTALNLVLDRVGGP -AALDAWLTDLGDDETEVVDQEPELNRPTAGSDANTTTPAASTADLRAVAVGDALAADDRA -QLLDWMSGNATGDALVRAGAPDGWVVADKSGGAG-GVRNDVAVVTPPGREPIVLSVLTAR -ND--ADYDDALVARAAAAVLAEf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas nasdae TaxID=172043 RepID=A0A0B4CQL5_9CAUL --------LSDLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRAQ -AGQERLDRRIPITTADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRD -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPDGQPVIVAAYYHA -TGTSDDANAAVIAEATRRAL--- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) TaxID=485918 RepID=C7PRN9_CHIPD --nNTRQKVNEIAATARGHVGVAMMSLENGDTM-TLNGNDHFPMQSVFKVPLAIAVLDQVD -KGKLSLDQVIHITKKELLPWSPIREKYPEGTLKLREVLAYTVSQSDNNGCDILFNLVGGT -AYVEQYIHGLGVDSMAIKANEERMASAWKVQYTNWSSPLATLQLLKGIHTGKYLSKASND -FLLKIMKETTTGPKRLRGMLPADAVVAHKTGSSDTAATNDAGIVTLPDGSHLAIVVFVSD -TKVNEAIREGVIARITRLFWD-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia vietnamiensis TaxID=60552 RepID=UPI0009C0E1A7 ------SPLAEIERRSGGRLGVFAIDTGSGRTL-GHRADERFLMCSTFKGLLAAQILARVD -SGSERLDRLVHYTENNLIFTSPVTKANVAHGMSIEALCRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--HGVLDTTTPKAIAATAQRLLLGDVLSAGSRV -RLERGMTDCKPGLNRIRAALPAGWLAADRPGTSVDRETNDYALVRPPGRAPLFVAIYYDA -PGVSLDAREAVLREAGSAFV--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044B99BA -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFIYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. Leaf280 TaxID=1736320 RepID=A0A0S9NL35_9CAUL --------LSGLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPSQSVANLERLFLDPALTAASRA -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -ARATDDANAAVIAEATRRAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BF9320B ---------AKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYIDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNTTGDNLIRAGVPGGWEVAD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis subsp. mobilis (strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL B-806 / ZM1) TaxID=555217 RepID=A0A0H3G2Y5_ZYMMA ----------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIEDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGA -LALTAFWRQLGDDQSRLDNIEPFLNETPYGGVENTTTPIAMARNLQKMLLGSLLSPSSRD -RLTGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPNKAIILSVYVWG -GTPTKDQLLGLFSKIA------- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD05570 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGNTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. SPF441 TaxID=2663795 RepID=UPI00129E03D8 -------DLADLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRRIPITTADMINHAPVTERAVGASLTIEQLIKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRA -LLLQWMTDTPTGQNRLRDGTPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -TRATDDANAAVIAEATRRAL--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0N9UYU2_SPHMC ------KAIRDLEARSGGRLGIAVVD-ARGKLVsADRGHERFAMCSTFKLLLAGQVLERAA --KGVSLRTPLAFTRADLVSWSPGTEKRVGPDQQLGMAARDAVVLSDNSAANLILKQMGGP -AAFTAALRRAGDSVTRLDRIEPELNENAPGDQRDTTTPIAMATSAAGYVFGNRLGAGHRQ -QLRGWMIESETGRKRIRAGLPQGWIAGDKTGTCGN-AYNDVAFVEAPDGRKYVIAIYLDR -SAVTGDEASAVIAEATRLTVE-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI00069FA5D9 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000E240CD7 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGEI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured Mycobacterium sp. TaxID=171292 RepID=A0A1Y5PKH7_9MYCO ----IEQRIAALEKRHNAFVGLYGQNLDSTQSV-AHRDGDLFAMCSTFKAYASARVLQMAQ -AGELRLTDTVVVDPTLLRANSPRTEPNVGKPMALSDLCAAALQVSDNTAGNLLLRVIGGP -PAITAFARSIGDDRTRLDRWETELNSALPGDPRDTSTPRALGGGILSVLTGTVLDEPHRK -QLEDWMRVNTT--SSVRAGLPPDWTTADKTGSGDFASTNDVGIAFGPHGERVLLAIMTRT -QSNDSPALRDLVAEVTTLA---- ->[subseq from] class A beta-lactamase n=1 Tax=Aliivibrio finisterrensis TaxID=511998 RepID=UPI00124D1EB9 ----TLETVEAIELSSSSTIGISVLDTATDTTW-SYKGDQRFPMMSTFKTLLCAQMLYNSS -NDLLDKEALTRVTQESIIPWSPITEKFIGETISTESACEATMLMSDNTAANIVLAQTGTP -TSLTLFLRLIGDDITRLDRIEPELNEAQKGDVRDTTTPNAMTNTLNELLFGQTLTTADKN -TLKGWMVNNKVSDPLLRSILPRNWSIADRSGAGGFGSRGITAVLWNEKRAPIIMSIYLTQ -TNLDMASRNQVIVEVGNAIFKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0005DE16E4 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WU68_9BACT -------AIKQIIQSSKGTVGVAVIGLEDNFSM-TMNDHKRFTLHSVYKFPLALAVLDQVD -KGQLSLDQKLHVTKKDLLPWSPLRDEHPNGGISLSELLGYTVSQSDNNGCDFLFRLLGGT -KNVQTYIRNLGIKDISIAATEEEVAKAWPVQYTNWSRPSAMLRLMVNAYRGKYLSQSSTD -FLWKLMRETSTGPNRMKGLLPPGTVVAHKTGTSGTNATNDVGIVTLPNGKHFAIVVFVAD -STDDQKTREGVIARITKVVWDYy ->[subseq from] Beta-lactamase n=2 Tax=unclassified Curtobacterium TaxID=257496 RepID=A0A4R1SUI9_9MICO --eRVRRALAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) TaxID=264203 RepID=Q5NL19_ZYMMO ----------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIGDYAPFAKAHLDKGMSVAELCQGAIEQSDNFCANKLLERSGGV -LALTAFWRQLGDNQSQLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD -RLTGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG -GTPTKDQLLSLFSKIAH------ ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. SGAir0440 TaxID=2579977 RepID=A0A4V1F825_9CAUL --------LSDLETRNGGRLGFVVQDAATGRKL-GWRGDERFVYCSTFKMYLAAATLLRAQ -AGQERLDRRISITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRA -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPSNGQPVIVAAYYHA -NRTSDDANAAVIAEATRRAL--- ->[subseq from] Beta-lactamase n=1 Tax=Moritella sp. JT01 TaxID=756698 RepID=A0A137SNQ8_9GAMM ---NIDASLRHIEQQIEGQIGVSVIDTENNTQW-SFNGTERFPMMSTFKTLACANVLYDVQ -HNMLSLTQKINVSKEGLINWNPITQHFIGAQMSLKSVCGAAMIMSDNYAANLALEQIDGP -KGVTAFLRSIGDNETRLDHFEPKVNYVKKGAKNDTTTPVAMMNTIRKLLIGNVLDAESKA -QLQVWMTNNMVSDGLARAVLPKGWKIADRSGGGVNGSRTLTAMVWKKDHKPVFVGIFIAN -SKKTLLELNKVVADISKQVFDKy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000BA5CE6C ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIGLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WVM4_9BACT --nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIAMAVLAQVD -QGKLKLDRKIRVETSDVLQGSRILDEKSQGMFSLAELLKYMVSESDGTSCNVLLRQVGEP -RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRAFHEGKGLSKSSQA -LLLQLMTETTTGPQRIKGLLPDGTVVAHKTGTSSTAATNDVGLVTLPNGRHMAIAVFVSD -SGANNATREGVIAKVTKAAWDEw ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2XPT6_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHIXKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0011A50F1C ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGISKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium ipomoeae TaxID=1210932 RepID=A0A4S8NZ33_9RHIZ -----LETAKSIEARLDLRLGYAMIGPTGEMQH-GYRADERFAMNSTFKALACAAALNRGD ----QVLDMRVTVRKGDILPHSPVTETRIGSTIAIRALCEITLRTSDNAAANLVLKAIDGP -EALTDFLRAKGDDVTRLDRFEPELNEAKPGDPRDTTTPRAMASTIRHLTLGSGLSPAASR -QLDAWMQANAVADGLLRKVLPKGWPIADRSGAGGFGSRGIVALIRPDTGDPVVVAIYMTG -KAHPLKVRDAAIAELGDAIF--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A085K8G2_SPHYA ---------KEIEEETGGRMGIALVDGDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKRNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPELNENVAGDPRDTTSPAAMAGLMGRLLFRDMASA-DAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAAIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. JUb34 TaxID=2485109 RepID=A0A3N1YFJ2_9MICO ---AVRRALAALEREYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKVFAAAQFLRSVP ---TDARDEVVHWTAADVAAYSPVTEQHVADGLTSAQLAEAAVRMSDNTALNLVLTRIGGP -SSLDAALAELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLNSADTA -LLVGWMGGNATGDALIRAGAPDGWVVVDKSGGAG-GIRNDVARVTPPDGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLGAf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium siliguriense TaxID=1136497 RepID=A0A1H1QQG5_9MICO -hqRLDEQLTNLEDRYDARVGVSALDTETGEAV-DHRADERFGFASTLKVFAVAELLDRTK ---PDDLEKNVTWTQADVDEWTPVTEKHVDDGLPLDDVAESALRVSDNLAMNIVLDELGGP -EALDDALEKAGDTTTEVTDEEPALNDVEDGSTDNTTTPAAFSAGLRDLLDPQRLSDEDRE -VLLNWMSANETGDSLIRAGAPDGWVVRDKSGHSD-AIQNDIAVVTPPDRQPIVISVMTET -DDPESEDGPALVAAVAEVVLDSf ->[subseq from] Beta-lactamase class A n=1 Tax=Williamsia sterculiae TaxID=1344003 RepID=A0A1N7CSA0_9NOCA ---RLEAQIVTAAARVRADIGVHAVDLASGVTA-DVHSGNRFPILSMFKVYAAAAILRDAR -AGKLSLQTPVRITRADIVSNAPVTSAHVNGTLTMAEIAQAALQHSDNTAGNLMLRQLGGP -AAVNALARSVGDTDTDLERWETALNDAVPGDVRDTTTPRAVATGFRSLLAGDGLQQQDRD -TLVGWMRGSATSAQRFRAQLPAGWTTADKTGSGEFGTTDDGGLLLGPGGRRILLVVQTRS -GTDDSNGYGDLVAEVARLVAQ-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=3 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00045189C0 ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia pyrrocinia TaxID=60550 RepID=B8XXQ7_BURPY ----AAATLAQLERTAGGRLGVCALDAASGRRV-EHRADERFPFCSTFKAMLSAAVLAQSV -ARPGLLQQRVTYGKADLVNYSPVAEKHVGAGMTVAELCEATIQYSDNSAANLLMKLLGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLGDTTTPAAMAASMRVLTLGDALPAAQRA -QLVTWLRGNKVGDKRIRAGV---------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578) TaxID=640132 RepID=D6Z9W4_SEGRD -----ESAVAALEARHKAHVGVFALDTGSGNTL-EHRADQRFMMCSVWKTLVVGLVLRRAQ -ADPGLLAAVIPADPGPIAEDSPFAKGRLGQTATYSELCGAAIRLSDNIAANILLQQFGGP -PAVTDFVRSLGDATTRLDRYEEEMNYGSPEDLLDTTTARALASTYQKLLLGDALAPPQRQ -QLTDWMEGTTTGLHRIRAGLPAAWRVADKTGTAGQGNANDVAIAWPDGGAPLAISVLTVA -PG-VAKPDDRLLADVASAA---- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI000BFD34D1 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPSAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacterium linens TaxID=1703 RepID=A0A144MWY4_BRELN -hqEVEDQLKDLEDRYDARVGVSALDTGSGDSV-DHRADERFGFASSLKVFAVAELLDRTT ---PKELEKNVTWTQADVDEWTPVTEKHVDDGLPLEDVAESALRVSDNLAMNIVLDEIGGP -KALDDALAKAGDTTTEVTDEEPELNDVEEGNTDNTTTPAAFTTDLQSLFDSQRLSDEDRE -VLFSWMSANETGDPLIRAGAPEGWVVRDKSGHSG-AIQNDIAVVTPPDRKPIVISVMTET -NDPESEDGPALVAAVAEVVLNEf ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A2Z4C251_STEMA ------------------RVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA----MSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGE-------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas vesicularis TaxID=41276 RepID=A0A1Z3U5S2_BREVE -------DLADLEARNGGRLGFVAQDAATGRKL-VWRGDERFVYCSTFKMYLAAASLLRVQ -AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSVANLNRLFLDPALTAASRA -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -TRATSDDANAVIAEATRRAL--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WPD0_9BACT --nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIAMAVLAQVD -QGKLKLDRKVRVETSDVLQGSRILDEKSQGMFSLAELLKYMVSESDGTSCNVLLRQVGEP -RIVTEYLRSLGINDIVVANTEKELAQDPAVKYRNYATPDATVVLLRAFHEGKGLSKSSQA -LLLQLMTETTTGPQRIKGLLPDGTVVAHKTGTSSTAATNDVGLVTLPNGRHMAIAVFVSD -SGANNATREGVIAKVTKAAWDEw ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus pettenkoferi TaxID=170573 RepID=UPI0011A6F911 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLVSETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0011A6976C ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCNVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM8_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVARPL--------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=E9LZM7_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMISTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVARPL--------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB146 TaxID=2485187 RepID=A0A4V2VI26_9MICO ----VRRAIAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066E9885 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB171 TaxID=2485195 RepID=A0A3N1NNN7_9MICO ---AVRRALAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013A6F1A7 ----HAKELNDLEKKYNANIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Plantibacter sp. VKM Ac-1784 TaxID=199708 RepID=A0A1Y6E978_9MICO -------EFQALEAEFSARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR ---GSARDEVVNWSAEDVEAYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP -AALDAALGALGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFTDNLTRLVDGSYLEPADRA -TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT -LDPDAEYDDALVAEAASVALAAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0004503364 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYTSTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00123182FE ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000E6806C8 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNVDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Xanthomonadaceae TaxID=191676 RepID=A0A2M9EPC5_9GAMM ---DAEQQLLDLQQTSAGRLGVYVLDSETRRHL-ALRADERFGMNSTFKLLLAAVVLRAME -EGEFAADMTLPFSADDLVPHAPVIQARLDNGMHMTELAKAAQLTSDNTAANLLIRQLGGP -EGVTARWRALGDQVSRLDRYETEMNFVPAGEVRDTTTPRAMAETVARLFVGDVLGDGARE -DLKGWMLATETGLKRLRAGFPPGWQIGDKTGSGFEGKTHDVAVIWREGRKPVVIAAYYEA -DAGVRDEDEAVLAGVGRIVQ--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. 18060 TaxID=2681408 RepID=UPI001356FB3B --eRVRRALAGLERQYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000B7ABC49 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -VLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000449A5E4 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1F3 TaxID=2080558 RepID=A0A2S5XR83_9MICO ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga filiformis TaxID=104663 RepID=A0A1G7XDK8_CHIFI -----RKKIHDIALTVHGHVGMAMMSLEDGDTI-TLNGKDHFPMQSVFKLPLAIAVLDQVD -KGKLALNQVIHIRKEDLLPWSPIREKFPEGTMKLSDILAYTVSQSDNSGCDLLFRLVGGT -AYVDKYIHSLGIDNIAIKATEEQASKAWEVQYTNWSSPIAMLQLLKGVHTGKYLSKASNE -FLLKLMTETTTGPKRMKGLLPENAVVAHKTGTSDTAATNDVGIVTLPNGKHYAIAVFVSD -TRADTATREGVIAQLTRLFWD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI000A0033E1 ---AVSDPIAQYERVTGGRIGVYAVNVKTGAKL-TWRADERFIMCSSYKASLAAFVLSRVD -RGEEKLDAAIRYGVRDTKDWGPVSKANLTKGMTVEAMCKAAVEISDGVCANLLLARSGGP -AALTAFLRSIGDGITRVDHYEPQLDRVPSGGPWDSTTPAAMAATLQKMVLGDVLSARSKA -LLTQWLIGNQT-NPRLRGGLPRSWLIGNKTGHSGRDMAGDIAVAWPRPDTPIVIAVYTRE -GRPTEKQFDEVFGGIGRLVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE83C01 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E3154D ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Listeria sp. PSOL-1 TaxID=1844999 RepID=UPI0013CF4490 ---TIESKFKRLEEKYQATLGIYAIDTKTTKEI-TYNQEERFAFTSTYKAIISGIILRNYT ---NEQLNKRIFYTAEDLVTYSPITQDHVSGGMTIREIIHAAITYSDNTAGNLLFNELNGP -KEFQNALEKIGDQVTHSDRYETDLNSAVPSDIRDTTTPTAFLKDLSFLMDPSHMNHEALA -YFKKTLIENTTGDHLIRAGVPDGYIVGDKTGAGSYGTRNDIAVIFSSDMKPFVWIIFSKM -VKKEDQYHDQLIADAAKLLSEYy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005E2BA2F ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLLLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=43 Tax=Bacteria TaxID=2 RepID=A0A6B0BAG8_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000E018B44 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPIRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura kijaniata TaxID=46161 RepID=UPI0009FEBD28 ---DLTKALQELEQSYNGRIGAVGIDLATGRTV-GHRADERFPFNSMFKVFACSAVMDKAR -TDPGLMDRVVRWKPADMAGNSPETKEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP -RGLTAFFRATGDRTSRLDRPEPYLTEWQPGEERDTTTPAAAARTFTKLTTGKVLHPRDRE -RLLGWLKASLAGADRIRAGLPKEWTVGNKSGTGGHGTANDMAIAWPPGAAPIILAVFTNR -TTDDTPHDAKVIQSTATALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Cryobacterium roopkundense TaxID=1001240 RepID=A0A099JG23_9MICO --sALQTALGELEDQYDARIGLSVTDTADGSTL-DYRGGSRFGYASTLKMLAAAALLDQTT ---PEELDRVVTWSEADVLEYSPVTSEHLDTGLPLGDVAMAAIRTSDNTAMNLMLKQFGGP -AGLDKILEGYGDTVTDVVDNEPGLNTVTIDNTANTSTPRAFTKTLERIVSGEILDDADRS -TLIDWMTGNATGDTLIRAGAPEGWEVADKSGGAG-AIRNDVAVVIPPDGIPLVITVFTTR -NDPDTAYDDALVAETARLAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D1C5AC ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYAATSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus sp. HMSC74G01 TaxID=1608906 RepID=UPI0008A94009 ----HAKELINLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium PA4 TaxID=2015572 RepID=A0A257EJA8_9PROT ---ALRAAVAETERSAGGPLGLMVRDTGSGASF-RHRADQRFPLCSTFKLLLAARLLAGGD ----WRMAEALPVTAADMLDPAPVTRPRIGGTATLRELAAAMVTFSDNPAANIALRRSGGP -AALTRWLRGLGDDITRLDRMEPELNNETPGDPRDTTTPAAMLATTERLVLGDVLTPTARA -ELIGWMAASQTGATMLRPALPAGWTEAHKTGAGSDRARNIVSLITPPNRPPILVSAYLFA -RESSLEARNAPFPALGRAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Listeria sp. CLIP 2019/00642 TaxID=2705293 RepID=UPI0014314109 ---SVNEKLEVLENKYHAKLGVYATN--GNEKI-KYNAQERFAYTSTYKAIISGLLLKNRT ---EEELQKTILFSKEDLVDYSPITEKFVDKGMTLKEIIHAAVAYSDNTAGNLLFDEIGGT -KKFQKALRKIGDNTTIASRYETDLNSAVPGDLRDTTTPEAFGMDLQRLTDPEYLNPQALS -YFKQTLVDNTTGDKLIRAGVPEGYIVGDKTGAGSYGTRNDIAIIFKENSAPFVWTVFSKM -DQEDAQYNDQLIADVAKVLSEEf ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium halotolerans TaxID=246613 RepID=UPI000E6AA443 ----LDDDLESLEDEFQARVGVSVLDTGTGATI-EYRSDERFGYASTLKVFAVAEMLRQVA ---PEQRDEIVTWTDETVAQYSPVTAEHVADGLTLAQLAEAALRDSDNAATNLILDRIGGT -EGLQAGLELLGDTTTDVADIEPELNEVVPGETGNTTAPAAFASGLAAVLKPEHLDPADRT -TLLEWMSANATGDALIRAGAPADWVVADKSGGAG-GKRNDIAVVTPPGQSPIIVAILTEK -YDPDAAYEDELVARVAEAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3Z0D2_9MICO ---EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT ---PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP -KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT -VLIDWMSDNETGDPLIRAGAPAGWTVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN -NDPNTESDAELIEDTAHAVLGAf ->[subseq from] Beta-lactamase n=2 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A3S8SMV1_9MICO ---EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSFAVAELLARTT ---PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP -KGLDSALEDLGDSTTEVIDREPDLNTIDPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT -VLIDWMSDNETGDPLIRAGAPAGWKVADKSGHAD-ALRNDVAVVFPPKRDPIVIAIMTEN -NDPNTESDAELIEDTAHAVLGAf ->[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI0001B705A0 ----------EYEQATGGHVGIYAQNIETGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIEDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGV -LALTAFWRQLGDNQSRLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD -RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPRPDKAIILSVYVWG -GTPTKDQLLGLFSKIA------- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. YB235 TaxID=1496080 RepID=UPI001421FA83 -hqRLEDQLKKLEARYDARVGVSALDTESGESV-DHRADERFGFASSLKVFAVAELLDRTT ---PKELEKNVTWTQADVDEWTPVTEKHVDDGLPLEDVAESALRVSDNLAMNIVLDELGGP -EALDDAMEKDGDSTTEVTDEEPELNDVEEGSTDNTTTPAAFTANLQGLLDAKRLSDDDRK -VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAMVTPPDRKPIIISVMTET -DDSESEDRPDLVAAVAEVVLDSf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00091220D7 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIESSMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus wiedmannii TaxID=1890302 RepID=UPI000BF1E4BB ------------------------------------------------------------- ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLIEIGDTVTNPERFEPELNEVHPGEIHDTSTPKALATSLQAFALGDILSTEKRN -LLIDWMKRNTTGDKLIRAGVPGGWEVADKTGSGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDAKYDDKLIAEATKIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Microbacteriaceae bacterium 13S1-3 TaxID=2144185 RepID=UPI000D371751 ---DVSAELTALEARYSARVGVSAMDTGTGREV-AFRAGERFAYASTLKVFVAAEFLRRVP ---AAERDAMVTWTRGDVDDYSPVTGARVAEGLPLAALAEAAVRSSDNAATNLLLDRLGGP -ASLDAGLEELGDTTSEVVHDEPALNRVSPGAVADTSTPLAFTANLRTLLLGDALAPADRQ -LLTEWMSGNATGDALVRAGAPEGWAVADKSGGAG-GIRNDVALVTPPGRDPILVTVFTEK -TDEGAAYEDRLVAETAAVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. 374 TaxID=1150400 RepID=A0A1H1APP6_9CAUL --------LSDLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRRIPITAADMINHAPVTEPAVGVSLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDDSTRSDRFEPEMNRL--DGDKDTILPNQSVANLQHLFLASALTAASRA -LLLQWMTDTPTGQNRLRAGTPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -ARATSDDANAVIAEATRRAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI00114F0D19 ----------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIGDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGA -LALTAFWRQLGDNQSRLDNIEPFLNEMPYGGVENTTTPIAMARNLQKMLLGSLLSPSSRD -RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG -GTPTKDQLLSLFSKIAH------ ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1K591_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVADH---------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WVN0_9BACT ---SLQKQFEEIASVAAGPVGVAVLEIETGELV-TLSGKQHFPMQSVYKLPIGMAVLQQVD -KGLLKLDQIVHVKPADLVPGSPLRDRHPQGAVTLSELLSLMVKDSDGTASDVLLNLIGGP -DAATKYLRELGVEDIVVATSERDMAGDVQVQYRNWSTPEAMVGLLKLLHEGRGLTAASRT -LLLDWMVKTQTFPTRLKGMLPEGTIVAHKTGSSGARATNDVGLITLPNGHHLAIAVFVSD -TKADAKTRDAVIARSARAAWDCw ->[subseq from] class A beta-lactamase n=1 Tax=Plantibacter sp. M259 TaxID=2583822 RepID=UPI0011103BA9 ---DLSVEFQALEAEFGARVGISAVDTGTGARL-SYRVDERFGYASTIKALAAAVFLHEVR ---GSARDEVVTWSAEDVDAYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP -AALDTALVTLGDEVTEVVNAEPQLNVIEPGSTDDTSTPAAFTDTLIRLVDGSYLESADRA -TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPSGDPIVLTILTNT -LDPDAEYDDALVAEAARVALAAf ->[subseq from] Beta-lactamase n=3 Tax=unclassified Curtobacterium TaxID=257496 RepID=A0A4R3U7U8_9MICO ---TVRRAIAGLEREYDATVGVVATDTVTGERV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112161 ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELMYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00132EF2F3 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQAP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB137 TaxID=2485182 RepID=A0A3N4VV40_9MICO ---TVRRAIAGLEREYDATVGVVATDTVTGERV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=D2J8J7_STAEP -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000B516E26 ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP ---HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLIKDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI000CD2B476 -----AKELNDLEKKYNTHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000458F496 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKSGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNIINKf ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus warneri TaxID=1292 RepID=A0A658D631_STAWA ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASKNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Chitinophaga sp. S165 TaxID=2135462 RepID=A0A317LLA1_9BACT ------NKVYEIAGAAQGHVGMAMLSLEDGDTM-TLNGNDRFPMQSVFKFPLAIAVLDQVD -KGKLALDEVIHIRKEDLMPWSPIRDKFPEGTMKLRDILAYTVSQSDNNGCDLLFRLVGGT -EYVNKYIHGLGIDSIAIKATEKQMGQAWDVQYTNWSSPVAMLGLLQKVYAGRYLSKTSND -FLLKVLRETTTCPNRMRGLLPKDAVVAHKTGTSGTAATNDVGIVTLPNGKHYAIAVFVSN -SKADEATRDAIVAQLTHLFWN-- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000D1BEAA8 ---ATTQDLKKVEDKYDANVGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHISKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNKDTSTPKAFGKTLNKLINDGHLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIILVIFTNK -EGKTDKPNDKVISETAKVVLEKf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000733F1E2 ---ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAVSSAMLLEKIP ---HNKLNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044DFEFB -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITFKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Hapalosiphonaceae TaxID=1892263 RepID=A0A4D9CCD2_MASLA ---ELYNRIEEISRTAQGRVGVAVTMLETGESV-TLNGDQRFPMQSVYKFPIGMAVLAQVD -QGKLKLEQRIRVEKNDFVSHSPIRDDNPQGVLSLTQLLKYMVSESDGTACDVLLKLVGGP -EVVMKYLRDLGINGINVINTEKEIGQDKSVQYRNWATPEAMIVLLRALHEGRGLSKSSQG -LLLRLMTETPTGLGRIKGMLPDGTVVAHKTGTSRTAATNDVGLVTLSNRQHLAIAIFVSD -STAEDAAREEVIAKVARAAWDKw ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio sonorensis TaxID=1004316 RepID=UPI0008D8EA66 --sELHQRLAEIESRVEGRIGIAFVDSATGFRW-SYRGNETFPVLSTFKPLACAKLLHDMD -SGQLNHDQSAYIKRDDIVEWSPVTKELTNSQISLISACEAALSMSDNTATNIVLNNIGGP -DALNQFLRKVGDKSTRLDDLEPFINQV--KERENTTTPVAMTNTMSHLFLGEGLSEGAQK -TILGWMERNRVSMALLRSVLPYGWSIADRSGSGSKGSRGITALIWKETRKPLVMSIYVTE -TNLTLSDRNQLIADIGEVIFS-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DA92618 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSKPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A2S6QBE8_9PROT ---TLVKSIKKIETDFDAKVGVAVYDLNTNDLW-SYNADETYPLMSTFKTLACANVLKQLD -EGKLSLDTEIKIDSSDIVTWSPVLKDKANQSLTIKQLCDAMMMQSDNSAANIILKTLGGP -ESITQFAKTLGQTKTNLTRNEPNLNNVTALDKIDSTTPNEMVRMLDSLLYTNILSEKSKL -QLLEWMKQNQVSDILLRSITPEDVNIADRSGANE-GGRAITAVVWNDKMKPIIIAIYIAH -SNLEQKYLHEAIVDIGEKIYRQf ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. ANC 4105 TaxID=1217703 RepID=N9MGG5_9GAMM ----LEEQVKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLSLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDIRDTTSPNAMNASMKKLLMGNVLSKSSKE -QLKEWMIGNKVADNMLRASLPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK -SETSLDQRSEVIKLLSDHIVKEy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI000C313BF0 -----AKGLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0001F48FFE ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATFASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000768EA1C ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A411G5Q2_PROMI --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITKSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRHDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRG------------------------ ------------------------ ->[subseq from] SGM family class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0013768B53 ---------KEIEEETGGRMGIALVDRDGALIL-GFNRDDRFAMCSTFKAPLAAAVLIGAQ -GGKFGLEGEIPFTKDDILDYAPVVKKNKKRGMSMAELAAAAVEVSDNSAANLLLPMLGGP -EGLTSFIRAHGDKITRLDRIEPDLNENIAGDPRDTTSPAAMAGLMGRLLFRDM-AAADAD -RLRGWLNASTTGDKRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPAGEEYILAIYLDR -PTVDDKKAEAGIAEAAHSAL--- ->[subseq from] Beta-lactamase n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=A0A1T5MBZ8_9BACT --kSLATAIDQVVRSIDAQTGVAILHIENRDTV-SVHGKAHFPMQSVFKFPLAMAVLHAVE -EGKFTLDQKIHVRKEDLLAWSPMAKKYPEGNVPLHELLMYTVSFSDNSTCDILFRLMGGV -KNVQKYIHDLGIKSIAIVATEEEMHREWSVQFTNWCEPVAMVQLLDILYKQKALSKDNTE -LLLKWMIETPTGAHRIKELLPAGTIVAHKTGTGGIGAINDVGIVTLPNGKHIAIAVYISR -TT-DEKKAEEAIAKIAKVAYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=UPI000B358824 -------DLSALEARHGGRLGVSVAT--EGQSA-AWRGDERFVYCSTFKMYLAAATLLRIQ -AGRERLDRAIPVTQADMISHAPVTKPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLILSESLESASKR -LLLEWMVASPTGQARIKAGVPAGWTVAHKTGTGGYGPVNDIGVLYPTDGAPIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C5 TaxID=2080538 RepID=A0A2S5XFW0_9MICO ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=UPI0009A55D9B --kSLATAIDQVVRSIDAQTGVAILHIENRDTV-SVHGKAHFPMQSVFKFPLAMAVLHAVE -EGKFTLDQKIHVRKEDLLAWSPMAKKYPEGNVPLHELLMYTVSFSDNSTCDILFRLMGGV -KNVQKYIHDLGIKSIAIVATEEEMHREWSVQFTNWCEPVAMVQLLDILYKQKALSKDNTE -LLLKWMIETPTGAHRIKELLPAGTIVAHKTGTGGIGAINDVGIVTLPNGKHIAIAVYISR -TT-DEKKAEEAIAKIAKVAYDYy ->[subseq from] Class A beta-lactamase n=2 Tax=Plantibacter flavus TaxID=150123 RepID=A0A4U3G0K4_9MICO -------EFQALEAEFGARVGVSAVDTGTGARL-SYRADERFGYESTIKALAAAVFLHEVR ---GSARDEVVTWSAEDVEAYSPVTSEQVETGLALSQLAEAAVRRSDNTALNLVLARIGGP -AALDAALVTLGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFADDLIRLVDGSYLEPADRA -TLLAWMSGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT -LDPDAEYDDALVAEAARVALAAf ->[subseq from] Beta-lactamase n=5 Tax=Staphylococcus aureus TaxID=1280 RepID=D2JKK7_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKNLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000BA7BBDD -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYSKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis subsp. mobilis NRRL B-12526 TaxID=1194424 RepID=A0A2R9NW34_ZYMMB ----------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIGDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGV -LALTAFWRQLGDNQSRLDNIEPFLNETPYGGIENTTTPIAMAHNLQKMLLGSLLSPSSRD -RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPDKAIILSVYVWG -GAPTKDQLLGLFSKIA------- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. NIPH 2100 TaxID=1217708 RepID=N9RPS0_9GAMM ---TLEEQIKTL-SEKGWQIGVSILDM-NDKLI-SFNGDKRFPLDSTVKALACANVLAKVD -AKKLSLDHAKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDKVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLAGNVLSKSSKE -QLKEWMIGNKVADNMLRAALPQGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] Beta-lactamase n=1 Tax=Bordetella holmesii CDC-H585-BH TaxID=1331206 RepID=A0A158M9I8_9BORD -------------------------------------------MCSTFKVLAVGAVLARVA -RGEDDLSRPMRLSAADIVAHSPVTQQRLNEGMTLGQLCDAALVVGDNTAANLLLSTIGGP -PGVTAYARSLGDAVTRLDRLETALNDATPGDDRDTTSPVAMAENLRQLVLGDALPGPERE -RVRDGLLHCQTGKGRLRAGLPAAWTFGHRTGAGGHGTCNDIGIAWPPSAGPVVISAYLTE -SPLPLPERERVLAEAGRIVVH-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A411G5R6_PROMI --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRHDSWEPELNEAIPNDERDTTLPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRG------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B5 TaxID=2080570 RepID=UPI000CE786B3 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=2 Tax=Acinetobacter beijerinckii TaxID=262668 RepID=N9EC93_9GAMM ----------NLLQQKGWKVGVSIFDSNSKKLE-SVNGDTRFPLDSTVKALACANVLSNVD -KGLLSLENKVLIEEKDVVSHSPVTMKLINKSITLRDACAATTAYSDNTAANIAISSVGGP -QKLTQFMRELGDTKTRSDRYEPELVINPEFDLRDTTTTDAMSESLSKLLVGNTLSKKSRE -QLKSWMMDNKVADNMLRARLPNGWSIADRSGASDYGIRGITSMVWSKTQEPLFISIYVRK -SNTTLDERSRVINEIGEVIFNRy ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf164 TaxID=1736282 RepID=UPI0009EAF10E ---ELDAALAALESEHGARVGLSVVDTGTGRAL-EHRGDERFLYASSLKALAAAALLDATE ---PADLDEVVTWTADDVAAYSPATSAATGTGLTLGQLAEAAVRQSDNTALNLVVEHLGGP -AALDAALAAQGDDVTDVVHGEPELNRPTAGSTADTTTPAAVRGLLARVVAGEWLGDDDRA -QLLEWMSGNATGDALVRAGAPEGWAVADKSGGAGP-VRNDVAVVTRPGGDPVVIAVLTTR -TDPAAAYDDALVAAAARAAFE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acidisoma sp. S159 TaxID=1747225 RepID=UPI00131A92C3 ---DAADSIADVERRYGGRLGVFAVDTGSGRTL-AYRADERFLMCSTFKGLLAGLVLSRVD -AGKEELTRMVGYGEKDLIFTSPITKVNVSRGMSVEALCQAMLEVSDNTAAVLLMRSVGGP -PGLTRFLRGLGDLTTRSDRYEPASNEY--SGMLDTTSPRAIVGSAQKILLGEVLSPRSRD -QLEAGMIACKPGLKRIRSALPPDWIAGDRPGTSLGEETNDYAIVRPPGHAPILVAAYYDA -PKLSMDAREAVLRNAGSAFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1D2 TaxID=2080543 RepID=UPI000CE81CD9 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDDALVARAAAVL---- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012ECE9B3 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIETSMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI0014332A94 ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] Penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=A0A6A2BTQ7_STAEP ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKSSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf263 TaxID=1736313 RepID=UPI0006FEF943 ---DASAELTALEAEFDARVGVSALDTGSGATL-VHRQEERFGYASTIKVFAAAAFLHDVP ---VDQRDEVVTWTAADVAAYTPVTSQYVDGGMSLVALAEAAVRTSDNLALNLVLDRIGGP -AGLDHALEQLGDTTTEVVADEPALNTIEPGSTDDTTTAAAFTADLAALATGDHLAAADRA -TLLDWMSGNATGDALIRAGAPDGWTVADKSGGAG-GMRNDVAVVTPPGRDPLVVTILTER -NDPDAAYDDVLVARVASVVLA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UIN6_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEKRFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVKELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKV------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta 3F5N TaxID=1255603 RepID=A0A1R4GS71_BREDI -------DLSALEARHGGRLGVSVAT--EGQSA-AWRGDERFVYCSTFKMYLAAATLLRIQ -AGRERLDRAIPVTQADMISHAPVTKPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLILSESLESASKR -LLLEWMVASPTGQARIKAGVPAGWTVAHKTGTGGYGPVNDIGVLYPTDGAPIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00066A6CEC -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000D1F8C3D ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP ---HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYNPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B9 TaxID=2080572 RepID=UPI000CE8C8BB ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nesterenkonia halophila TaxID=302044 RepID=UPI0012912873 -------AVDQLEQEYDARVGVSMIDLDDGSTL-SHRGGERFGFASTMKAFAAAALLHSTG ---AEERGQLVRWTSADIEAYSPVTEQAVDTGLTLGELAEAAVRQSDNTAMNLIVEHLGGP -EGLQRALEGIGDSVTRPVDREPELNDVVAGETANTSTAEALAGNLERLVAGEWLDEDDRR -MVMDWMGGNATGDTLIRAGAPEGWSVAEKSGGAG-AMRHDVAVLQPPEGEPIVLVVLTER -NDADAEYEDALVADVAEAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. MB371 TaxID=1663557 RepID=A0A1T1DCG3_9STAP ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP ---HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000E693F61 ---ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAVSSAMLLEKIP ---HNKLNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSKTAKVVLEKf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X795_9BACT --eSLRKEIENLVRPVNGSIGVGVRHLESGDTL-TIHGKDHFPMQSVYKFHLALAVLSDVD -QGKLSMDQKVLIRKEEFIPVSPIADKYPDGNLTVSELLSYTVSNSDNNGCDILFKLVGGP -KKVEAYIRGLGVRDVAIVNTEREMHQDWDAQFNNWTTPQGMVQLLDLFYQKKILSPESRD -FLVKIMEQAATGKKRIKGQLPAGTVVAHKTGMGGNDAMNDVGVVTLPSGGHFAIALFVTN -PKDSIEVVEAVMAKISKLVLDHy ->[subseq from] Beta-lactamase n=10 Tax=Staphylococcus TaxID=1279 RepID=A0A1D4EG02_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00107230B1 ---ATTQDLKKVEDKYDANIGVYALNTETDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNIIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TCM1 TaxID=453246 RepID=A0A196MVB3_9SPHN ---------AEIEKETGGRLGVALVD-RSGALLlGFNRDERFALCSTFKGPLAAAVLLGAE -AGKFGLEGEISFGKDDILDYAPVVKKNRKRGMSMGELAQAAVEVSDNSAANLLLPMLGGP -PGLTAFMRAHGDRVTRLDRNEPALNENAEGDERDTTSPAAMAGLMGRLFFRDM-KPESAD -RLRAWFNASSTGDHRIKAGLPEGWTSGSKTGTCGT-AYNDVALVKSAAGDEYILAIYLDR -PTVDAGKAEAAIAETARAALD-- ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium endophyticum TaxID=1522176 RepID=UPI00141DFE2C ---ELDAALAALESEHGARVGLSVVDTGTGRAL-EHRGDERFLYASSLKALAAAALLDATE ---PADLDEVVTWTAGDVTAYSPATSAATGTGLTLGQLAEAAVRQSDNTALNLVVEHLGGP -AALDAALAAQGDDVTDVVHGEPELNRPTAGSTADTTTPAAVRGLLARVVAGEWLGDDDRA -QLLDWMTGNATGDALVRAGAPEGWAVADKSGGAGP-VRNDVAVVTRPGGDPVVIAVLTTR -TDPAAAYDDALVAAAARAAFE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E8 TaxID=2080555 RepID=UPI000CE89263 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLETLGDTTTEVVNEEPALNTIEPGSTDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI001290BD16 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYSSTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDG4_ECOLX ---ETLVKVKDAEDQLGARVCYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLR------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Taibaiella soli TaxID=1649169 RepID=A0A2W2A739_9BACT --eDLKQNIQKITAGKKAEVGISIRGIENGKTV-SINGNKHYPMQSVFKFPIALTVLHQVD -AGKLKLEQLITIKRSELLQWSPLREKYPKGDIPLSEIIQYTVSQSDNNGCDVLLRLIGGP -AVVNDYIHSLGVKDIAIKANEEAMHKDWNVQFTNWCAPDAMTALLIKFYQQKILQPTTHA -FLWKTMAETTTGKNRIRKLLPAGTIVADKTGSSGTAALNDVGVVTLPNSQHFAITIFVSD -SKENNDTNEQIIADIAKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI0004244673 ---SVERALAALERRAGGRLGVSIVDTGRGTTI-GWRAHERFTQASSFKLSLAALILAEAD -RGRLVLTERLGWSAGDILPHSPVTTASAAMTLPIRELARAAVVTSDNTAANVLLRKIGGP -ARLTAFWRAGGDRVSRLDRYEPALNVTPPGTTLDTTTPAAMAATVARLVRGPVLRPASRA -LLTEWMVAANTGRHRLRAGFPADWYAGDKTGTGGRPIFVDLAFACPRGRAPLIVAAYFEP -VRASSESAEAVLAKVGRIAAGSf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005DDB270 -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELEDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE8A922 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000BBE33F6 ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNIIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00132FD48C ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNIIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000110FF8 ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSHAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G3U2_9SPHN ----ASDPIAEYERATGGRIGVFAINVKTGAKL-SWRADERFITCSSYKASLAAFVLSRVD -RGEERLDALVPYTVKDTLDWGPVSKANLAKGMTVEAMCKAAVEISDGVCANLLMARSGGP -LALTAFLRSIGDRATRIDHYEPQLDRVPSGGPEDSTTPAMMASTLQKAVLGKVLSDQSKA -LLTRWLVGNQT-NPRLRGGLPTSWRIGNKTGHSGRDMAGDIAVAWPRPDTPIVIAVYTRG -GRPTEKQFDQAFAGVGRLVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1D1 TaxID=2080542 RepID=UPI000CE8114F ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. GW460-12-10-14-LB2 TaxID=1827469 RepID=A0A160HZH1_9CAUL --------LADLEARNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKIYLAAATLLRAQ -AGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDGSTRSDRFEPEMNRL--DGDKDTILPNQSIANLQRLFLDPALTAASRA -LLLQWMTDTPTGQNRLRAGAPANWRVAHKTGTGGYGPTNDIGLLYPPNGQPVIVAAYYHA -TRATSDDANAVVAEATRRAL--- ->[subseq from] Beta-lactamase n=1 Tax=Chlorogloea sp. CCALA 695 TaxID=2107693 RepID=A0A2T1E3G7_9CHRO --nELHDRIEQTSRAAQGRVGMTATVLETGESV-SLNGNQRFPMRSVYKFPIAMAVLAQVD -QGKLKLDRQIRVEASDIVQGSRILDRNSGVELSLTELLKYMVSESDNTACDVLLRLVGGS -KIVTQYLRGLSVNDIIVANTEKELGQDTAVQYRNYATPDAIVVLLRTFHEGQGLSKSSQA -LLRRLMTETSTGLNRIKGLLPEGTVVAHKTGTSSTAATNDVGLVTLPNSRHLAISVFVSD -SMADDTTREEVIAKVARAAWDEw ->[subseq from] Beta-lactamase n=1 Tax=Celeribacter baekdonensis B30 TaxID=1208323 RepID=K2K1M7_9RHOB -----DSYMDRMERELSARIGVYVKNLGTGQAY-QRRAGERFAMCSTFKASLAALCLWRSD -HGELDLNEALAFNGMSFLPTSPVTKDHASAGMDIRSLCKAAVEFSDNTAANLLLARVGGP -KAVTAFFREMGDDISRLDRIELALNSNIPGDERDTTTPLAMAHNLQQMTMSGVLSVASTD -LLTKWMRNEQNAKNRIRAAVSSDWVVANKPGTTPNGAANDIAALWSPGGDALVMAIYIDT -EKGNTRAAVAAIRDISASA---- ->[subseq from] Beta-lactamase n=1 Tax=Plantibacter flavus TaxID=150123 RepID=A0A3N2BXV6_9MICO ---DLSVEFQAVEAEFSARVGISAVDTGTGARL-SYRADERFGYASTIKALAAAVFLHEVR ---GSARDEVVTWSAEDVEAYSPVTSEQVETGLTLSQLAEAAVRRSDNTALNLVLARIGGP -TALDAALVALGDEVTEVVNAEPLLNVIEPGSTDDTTTPAAFADDLIRLVDGSYLEPADRT -ALLAWMGGNATGDTLIRAGAPAGWQVADKSGGAG-GIRNDIAIIDRPGGDPIVLTILTNT -LDPDAEYDDALVAEAASVALAAf ->[subseq from] Beta-lactamase n=2 Tax=Neoasaia chiangmaiensis TaxID=320497 RepID=A0A1U9KS83_9PROT -------PMATIERRHGGRLGVYVRDLASGRHI-AQRADERFMLCSTFKAILAAMVLDRVD -HGQDTLAAMLPYRAADLRPASPVTTAHLREGLPIGALCHAIMAFSDNAAANILLAHCGGP -PALTDFVRRVRDSTTRFDRYETESGH--RDGDKDTTTPHAMTHTLETLLWGPTLQPSSRI -QLADWMQGNQVGARRLRAGFPPDWTVGDRTGTGD-GFCNDCAFAHLPDGRTIMATVYYDA -PGMTTAAQEAVLREVAVAIA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E4 TaxID=2080552 RepID=UPI000CE81225 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWNVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B3 TaxID=2080569 RepID=UPI000CE73440 ----VSAELAALESEFDARIGVSAVDTGSGRRV-EHRSNERFGYASSLKALAVAEFLRTVP ---AAERDEVVTWTAADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRIGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGEVLSAEDRA -LLLDWMSGNATGDALVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodobacteraceae TaxID=31989 RepID=UPI00125F4628 -----DSYMDRMERELSARIGVYVKNLGTGQAY-QRRAGERFAMCSTFKASLAALCLWRSD -HGELDLNEALAFNGMSFLPTSPVTKDHASAGMDIRSLCKAAVEFSDNTAANLLLARVGGP -KAVTAFFREMGDDISRLDRIELALNSNIPGDERDTTTPLAMAHNLQQMTMSGVLSVASTD -LLTKWMRNEQNAKNRIRAAVSSDWVVANKPGTTPNGAANDIAALWSPGGDALVMAIYIDT -EKGNTRAAVAAIRDISASA---- ->[subseq from] Beta-lactamase n=1 Tax=Cryobacterium sp. TMT1-51 TaxID=1259239 RepID=A0A4Y8JS35_9MICO --sALQTALGELEDQYDARIGLSVTDTADGSTL-NYQGDSRFGYASTLKTLAAAALLDRTT ---PEQLDRVITWSEADVLEYSPVTSEHIDTGLPLGDVAMAAMRASDNTAMNLMLKQFGGT -AGLDKILEDYGDNLTDVVDNEPGLNTVTTDNAANTSTPRAFTKTLERIMSGEILDDADRS -TLIDWMTGNATGDTLIRAGVPEGWEVADKSGGAG-AIRNDVAVVIPPDGIPVIITVFTTR -NNPDAKYDDALVAETARLAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C79C079 --------------------------------------------MSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIAV----- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A2W4QI94_9PROT -------DLAALEATHGGRIGVCAMS--EGGIV-KWRAGERFPYCSTFKLFLAASVMERVQ -DGLEKLDRAVPIAESDMVPHAPVTGPAVGSSLTIMQLLKATVEVSDNPAANILFREMGGL -EVFQKWYRSIGDRITRVDRNEVALNSALPGDHRDTTTPQQCVANLHSVLRRSLLSAGHLE -MLEKWLTETPTGTLRIKAAVPANYKVGHKTGTGAQNTRNDIGIIWPPRGAPILIAVFFTG -ARNAAEELDAIVAGSARAALQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Stakelama pacifica TaxID=517720 RepID=A0A4R6FF27_9SPHN --------FDKLENAVNGKLYLAVLDTGTGHRL-TWNADQRVGLCSTFKLPLAAAVMAGAE -KGTLSLDTPVSISAADLLDYAPAVKANLAKGMTIGELARAAVTVSDNSAANLLLPQVGGP -RGLTRYLREAGDTVTSIDHPEPLINRVRPGQDADSTTPWAMAGLVNDLLFSQLLTEAHRR -TLAQWMIDSETGLKRIRAGLPVNWKAGDKTGTSGDGWYNDVAVAWPGEGRPIVIASYLWA -PDGQPDAADAVHAKIGELVG--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis lucentensis TaxID=53441 RepID=UPI0003744E84 ---EHAERFAALEERYDARLGVFAVDTGTGETL-AHNADDRFAYASTHKAFSAAAVLRRSS ---DEDLERVVTYAEEDLQEYAPIAKENLDTGMTLLEVCDAAVRYSDNTAANLLFDELGGP -SGLQEELREVGDDVTHVDRIEPGLNEAAPGDIRDTSTPRAMATTLRAYALGDVLPEERRE -VLVDMLRRNVTGDTVIRAGVPDDWTVGDKTGTAGYG------------------------ ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura viridilutea TaxID=58112 RepID=A0A2P6ULD6_9ACTN ---EVTRRLRELEASYHGRIGAFAIDTGTGRTV-GHRTHERFPSNSTFKAVLCGAILHKAR -TADPGLMERRHYTAEEAKKHAPVTSENIENGLTTAELCHATITVSDNGAANVLLKQIGGP -KGLTRYYRSLGDPVGRLDTYEPELNEWEPGQKSNTIMPAFMARDLAKLTTGDALVPEDRR -QLNEWLKATTTGGTRIRAGLPDDWTVGNKTGTGGYATASDIAVAWRPSGAPLIFAVYTHR -DGRHPEIDDGVIAQTASILA--- ->[subseq from] Beta-lactamase n=1 Tax=alpha proteobacterium AAP81b TaxID=1523432 RepID=A0A0N1LGQ1_9PROT ---DLAATIATIEAR-SGRFGVAARDLASGWRF-AHRGDERFALASTFKLLLAGAILTAVD -AGRLRLAQTLHVTASDLVSYAPVTETLVGRRASLATLCDAAVTLSDNAAANLLLPLVGGP -AGLTRWLRRLGDPVTRLDRFEPALNLVPPGEVRDTTTPDAMLASVIRL--RDRLSAASRA -RLDAWLIASRTGGRRLRAGLPATWIVGDKTGTAS-GIANDVAIAWRPGVRPLLIAAYRAD -GG-DGAMADADHTTLARA----- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00119E5B96 ------------------------------------------------------------- -------GRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia brevicatena TaxID=37327 RepID=UPI0009FEADAB -------TLAELEDRHSVRLGVHAVDPRRELAY-IRRADERFALCSTFKVYAVAALLRQEQ -QGRLSLNDRVRIEPDEVVENSPVTEPAQGRAVALTELCEAALTRGDNTAANLILGRLGGP -RAITEFARTLGDNATVLNRWEPALNSAERGDLRDTTTPAGLGIGYRELLLGAALTPARQR -ILTDWMLANITSGERIRKGLPDGWTSADKTGAGSYGTVNDAGVVRSPNGDPLLLILLSDS -TTSDAPNNNVPLAEATTAIVT-- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia flavorosea TaxID=53429 RepID=UPI0009FFDD8B ---DLSNTLMEIQERHDVLFGIAAYSPTGARTF-EWNATDRFALTSTFKVYAVAALLRLAE -RGEVDLNEQVPILRSDIVIASPTTSYRAGETLSWYDLCQATLVRNDNTAANLILRRIGGP -PAVTALARTLGDTQTRLDRWEPALNEALPGDTRDTSTPAAFAGGLHRLVLGNALIPEHRR -MLTGWMRSSVTSGERMREGLPVGWVAADKSGTGAYGTVNDAGVVWSPTGTSVVLVIFSRS -TIPMAAPSDQAIADATTAVLE-- ->[subseq from] BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000111911 ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYDIELQYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=3 Tax=Brevundimonas TaxID=41275 RepID=A0A246K7L6_BREDI ------LDLSALEARHGGRLGVSVAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTQPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -EALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAIYFRA -TKSTDAQREAVIADATRQALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1F9 TaxID=2080563 RepID=UPI000CE85479 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDTEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. MYb31 TaxID=1848616 RepID=A0A2S8W5H1_9CAUL -------DLSDLEARHGGRLGLAVAS--GGVNA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAVAITAADMINHAPTTEKAVGSTLTVEQLMQATVELSDNPAANILIREMGGL -ETLRAFYRGIGDDSTRVDRLEPEMNRA--DGDKDTITPIQSVQNISRLLVDTPLNAASKA -LLMRWMTQTPTGQGRIKAGVPAGWTVAHKTGTGGYGPTNDIGLIQPPTGAPVVIAVYFHA -TRESDAQREAVIADATRLAL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138AFB6E ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTSAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVISKf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A2L0W0L8_9BACT ----LKEKIARIVAPMKAEVGVSVLGIEDGKAL-SVNGENKFPMQSVFKFPIALAVLSEVD -KGRFALDQEMDIGKSDLLPWSPIREKYPDGNMSLAEVLKYTVSQSDNNGCDILLGLIGGP -EVVNDYIHGLGIKDFSVQFNEQEMHQDWNIQFSNWATPVAVTELLRIFYERKNMSLKSFD -FLWGVMMETKTGPNRIKGQLPPGTPVAHKTGTSDTAAVNDVGIITLPDGKHVAIAVFVAN -SREDSATNEKIIADISRAVWDDf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E1YXE4_SPHSX --------FDKLENAVNGKLYLAVLDTGTGHRL-TWNADQRVGLCSTFKLPLAAAVMAGAE -KGTLSLDAPVSISAADLLDYAPAVKANLAKGMTIGELARAAVTVSDNSAANLLLPQVGGP -RGLTRYLREAGDTVTSIDHPEPLINRVRPGQDADSTTPWAMAGLVNDLLFSQLLTEAHRR -TLAQWMIDSETGLKRIRAGLPVNWKAGDKTGTSGDGWYNDVAVAWPGEGRPIVIASYLWA -PEGQPDAADAVHAKIGELVG--- ->[subseq from] class A beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=UPI000B399C7E ----------EYEQATGGHVGIYAQNIATGKSL-AWRANERFLMCSSFKVSLVASVLLRCD -RGQDSLDRIISYKPEDIGDYAPFAKAHLDKAMSVAELCQGAIEQSDNFCANKLLERSGGA -LALTAFWRQLGDNQSRLDNIEPFLNETPYGGVENTTTPIAMAHNLQKMLLGSLLSSSSRD -RLIGWMVRCQTGSQRLRAGLPKNWVIADKTGTNGHDAASDIAILWPQPNKAIILSVYVWG -GAPTKDQLLGLFSKIA------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D2XSF4_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAEXXXXXXXXXXXXXXXXXXXXXXXX -XXVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas vancanneytii TaxID=1325724 RepID=A0A4P1KA76_9CAUL ------LDLSALEARHGGRLGVSAAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMQATVEVSDNPAANILIRELGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTVTPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGAYGPVNDIGLILPPNAAAIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter gyllenbergii TaxID=134534 RepID=A0A1B8UG29_9GAMM ---TLEEQIKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLTLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -VGLTSFMRSIGDEVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLTGNVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] PROTEIN (BETA-LACTAMASE) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000112163 ------KELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYQIELDYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Dyadobacter flavalbus TaxID=2579942 RepID=A0A5M8QGE7_9BACT --dELKAKIDSISKLVQGTVGIGIMDLKSGETL-YLNEKHQFPMQSVFKFPLGMAVLDQVD -KGKLSLDQKIHVKKEDLNPWSPLQKKFPEGNLSLRELLTYTVSLSDNNTCDILFRLVGGP -RNVNKYMQSIGVKGINIVATEAEMAKNWDVQFTNWCRPPAMIQLLDVFHQGKKLSKSSTE -FLMKIMTETPTGLNRIKGLLPENTKVAHKTGSSGTNAFNDAGIVTMPNGKSIAIVAFVSN -TPADEKTRDMVIAQISRAAWDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9X047_9ACTN ------------------------------------------AYASTWKALAAAEVLDGAT ---DAQLDRVVRYSARDLVTHSPITEKHVGEGMSLRALADAAVRHSDNTAGNLLLRHLGGP -AGFESKLRALGDTVTDAARHETALNEGTPGDRRDTSTARALAGDLRAYTVGVALEPADRD -VLRGWLRGNTTGATLVRAGVPAGWVVGDKTGTGGYGTRNDIAVIWPPDRAPIVLAVLSTR -GKKDATPDDALTAQATRVVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=A0A2T4RV07_STASC ---ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAISSAMLLENTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIDELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGHLSKENKT -FLIDLMVHNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1H2 TaxID=2080566 RepID=UPI000CE8E855 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEATVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRSGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. NIPH 1867 TaxID=1217702 RepID=N9R0C2_9GAMM ---TLEEQIKTL-SDKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLSLDHSKTIRQKDLVTYSPVVKEYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -VGLTSFMRSIGDEVTRSDRYEPELVINPEGDIRDTTSPNAMNASMKKLLMGNVLSKSSKA -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE75369 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRSGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1F6 TaxID=2080560 RepID=UPI000CE7B5FD ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDVALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. PhB172 TaxID=2485196 RepID=UPI000F4B7B79 ---AVRRALAGLEREYDATVGVVATDTVTGATV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVAEGLSYGQLAEAAVRMSDNTALNLVLTRIGGP -SGLDTALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Curtobacterium TaxID=257496 RepID=A0A4R1SDF8_9MICO ---AVRRALAGLEREYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKALAAAQFLRSVP ---VDARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLGAf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. PhB78 TaxID=2485102 RepID=A0A3N2GID1_9MICO ---TVRRALAGLEREYDATVGVVATDTVTGETV-AYNSDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVRWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALTTVLDGSTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASAVLDAf ->[subseq from] class A beta-lactamase n=1 Tax=Blastomonas sp. AAP53 TaxID=1248760 RepID=UPI0002ECCBE1 ---TIRADLAAIEARSGGRLGVALVDQ-DGRQVaGHRADERFALCSTFKLPLAAMVLEKAA -EGRWAMGDALPVTDADMVAYAPYVEAQRDKSVTVEGAAAAAVSLSDNAAANLLLDRLDGP -QGFTAWLRGKGDAVTRLDRREPKLNENAIGDLRDTTSPLAMAETTRRLVIGDAMPLGQQR -LLYRWMEDTATGLKRIRAGLPQGWSAGDKTGSCGN-AFNDVAVFTTAKGRRYALAVYLDR -PVVKGDDASAILADATRAL---- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis sp. TNDT3 TaxID=2249354 RepID=UPI000E3C1CF2 -----ADEFADLEEEFDARLGVYAVDTGSGEEV-AHRPDERFAYCSTHKAFSAALVLQRNT ---PEEMEEVVTYDADDVFGHSPVTEQHVDTGLPLMEVADAAVRYSDNTAANLLFGELGGP -DGFEGAMEEMGDDVIEADRVEPGLSRWAPGDTRDTSTPRAMAGSLREFVLGDALPEDRRE -VLTRMLVDNLTGDELIRAGVPEGWEVGDKTGSGNYGTRNDIAVIWP-------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A0U2CIP0_STAEP -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPPAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Inhella crocodyli TaxID=2499851 RepID=A0A437LH10_9BURK -----PPSLAALERRHGGRLGVAVLDTGSQRLW-GHREDERFGLCSTFKLLLAAAVLQQID -AGRLAADRWVPFHGAPKVPNSPVTDAHQAAGMTLLALAQATQTTSDNLAANLLMRELSGP -QWLTQWLRERGDAVTRIDRWEPEMNHVPPGEVRDTSSPAAMARTAALLLTGPVLQPPHRE -LLQGWTEATRTGLKRLRAGFSEGWRAGDKTGTGWADKINDVAIVWPPGRAPWVVAAYYEA -PRHTRPQDIAVLAAVGREVT--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella sp. YJ22 TaxID=1104780 RepID=UPI001408E949 ---QADSRLADIERRTGGRLGVALLD-GRGRTVlGHRTGERFAMCSTFKFQLAAMMLDGAD -DGRWRMEDVLPLTPADTVRHAPVAERLLPTGITLAQAAAASQIQSDNATANLLLRRVGGP -AAFTAWLRGIGDSETRLDRYELELNENRPGDPRDTTTPTAYGETMRRLIFGDVLGGPSRE -QLRAWTSATTTGQRRVRGALPAEWPAGDKTGTCGT-AFNDIAWFRSPDGAEWVLAAFLDR -PIVPAAQAEAALAEVTAIALE-- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000D1E03AB ---ATTQDLKKVEDKYDANVGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNKDTSTPKAFGKTLNKLINNGHLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. PhB151 TaxID=2485189 RepID=UPI00106350C4 ----VSAELAALEAEFDARIGVSAVDTGSGRQV-LHRQDERFGYASSIKALAAAEFLRSVP ---ADERDEVVTWTAADVEAYSPVTGESIDGGLPLAQLAEAAVRRSDNTALNLVLDRLGGP -VALDRALEQLGDTTTDVVDDEPALNTIASGSTANTTTPAAFTADLTAVALGDALPAADRA -LLLDWMSGNATGDALIRAGAPEGWTVADKSGGAG-GLRNDAAVVTPPGRDPIVLSVLTSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=A0A0S3F4M7_9SPHN ---------KMIEEETGGRLGVALVDSSGALIL-GFNRDDRFAMCSTFKAPLAAAILLGAE -GGKFGLEGQVSLTKDDLLSHAPVVKQNLKRGLSMEELAAAAVEVSDNSAANLLLPMIGGP -EGLTAFFRAHGDSLSRLDRKEPDLNENEAGDPRDTTSPAAMAGLMARLLFKDM-KPESAE -KLRSWLDQSKTGDHRIKAGLPEGWTSGSKTGSCGT-AYNDVALVKSPTGAEYLLAIYLDR -PTVDEAKAEAAIAETAASALD-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCJR17_020 TaxID=2175619 RepID=A0A2W1U324_9MICO ---TVRRALAGLERQYDATVGVVATDTVTGETV-AYNGDRRFGYASTIKAFAAAQFLRSVP ---ADARNEVVHWTAADVAAYSPVTEQHVADGLSYEQLAEAAVRMSDNTALNLVLTRIGGP -SGLDAALTELGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTAALATVLDGRTLDRADTA -LLVDWMGGNATGDALIRAGAPDGWVVVDKSGGAGP-IRNDVARVTPPGGDPIVLSVLTTR -NDPDAAYDDALVARSASVALGAf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sp. 239c TaxID=1965356 RepID=A0A2H1KXU2_9MICO --qKVSGELESLEEDFKARIGVSAVDTGNGTSF-DYRSDERFGFASTLKVFAVAELLARTT ---SADLDEQVTWTQADVDEWTPVTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP -QELDAALEDAGDPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDPDRLPEDDRE -VLLEWMSDNETGDPLIRAGAPKGWTVKDKSGHSD-GIQNDIAVVYPPNEDPIIITVLTQS -EDPDSEDGPALVAAAAEAVFDSf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Xanthomonadaceae TaxID=191676 RepID=A0A2M9ENL0_9GAMM ---DAEQQLLDLQQTSAGRLGVYVLDSETGRHL-ALRADERFGMNSTFKLLLAAVVLRAMG -EGEFAAEMTLPFSADDLVPHAPVIQARLDNGMHMIELAKAAQLTSDNTAANLLIRQLGGP -EGVTARWRALGDQVSRLDRYETEMNFVPAGEVRDTTTPRAMAETVARLFVGDVLGDGARE -DLKGWMLATETGLKRLRAGFPPGWQIGDKTGSGFEGKTHDVAVIWREGRKPVVIAAYYEA -DAGVRDEDEAVLAGVGRIVQ--- ->[subseq from] Beta-lactamase n=1 Tax=Polyangium fumosum TaxID=889272 RepID=A0A4U1JHR3_9DELT ---RLERDVAAAETRAGGRLGVAVVEPSSGQRW-VHHAGERFPLQSTFKAPLAAAVLARVD -AGALSLDTKIEVRRDELSVWSPLAEAFQGETFSVLDLLTQSVAVSDNTAADVLMHEIGGP -ESVNAMLARSGVTALHVDRYERDLQLAYLRDPRDTTTPEAAADFLLKLDRGEMLTPASTR -VLLDIMHGTKTGPRRLRAGLPPDARLAHKTGSSDNGATNDIGIATLPDGRKLVIVALLTE -SSAPQETREAALADVARAAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter dispersus TaxID=70348 RepID=UPI00132E8822 ----LEEQVKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLSLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDMQDTTSPNAMNASMKKLLMGNVLSKSSKA -QLKDWMIGNKVADNMLRAVLPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter sp. TUM15071 TaxID=2609135 RepID=UPI00124D01BC ----LEEQVKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLSLDHSKTIQQKDLITYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -AGLTSFMRSIGDEVTRSDRYEPDLVINPEGDMRDTTSPNAMNASMKKLLMGNVLSKSSKA -QLKDWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] Beta-lactamase n=2 Tax=Caballeronia sordidicola TaxID=196367 RepID=A0A2C9XW84_9BURK ---AAESPLADIERRRGGRLGVFAIDTGSGRTL-SHRADERFLMCSTFKGLLAAQILARVD -SGAERLDRVVRYTKKDLIFTSPVTKANVARGLSIDALYRAILVESDNTAAILLMRSAGGP -AALTRFVRSFGDTVTRSDRYEPDSNRY--HSVLDTTTPKTIATTAQRLLLGDVLSAGSRA -KLERGMTDCKPGLNRIRAVLPVGWQAADRPGTSVESETNDYALVRPPGRAPLLVAVYYEA -PGVGMDAREAVLREAGTAFV--- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI0008076F53 ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNIYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A3S8SXP4_9MICO ---EVDSAIADIEKKYDARVGVHAMDTSDGSTI-EHRSKERFGFASTIKSLAVAELLARTT ---PAELDEHVTWTKEDVEKYAPVTEKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP -KGLDSALEDLGDSTTEVIDREPDLNTIGPGSADNTTTPAAFSNDLAALLEPEHLSDEDRT -VLIDWMSDNETGDPLIRAGAPAGWTVADKSGHAD-ALRNDVAVVFPPRKDQIVIAIMTEN -NDPDTESDAALIEDTAHAALGAf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A359KBV5_9CAUL -------DLSALEARHGGRLGVSVAT--EGQRA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -EPFRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGVLYPTDGAPIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas bullata TaxID=13160 RepID=UPI000E0AA8A6 ----LDLDLSDLEARHGGRLGLAVAS--AGVNA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPITAADMINHAPTTEPAVGSTLTVEQLMKATVELSDNPAANILIREMGGL -EALRAFYRGIGDDSTRVDRLEPEMNRA--DGDKDTITPIQSVQNISRLLVETPLNAASKA -LLMRWMIDTPTGQGRIKAGVPAGWAVAHKTGTGGYGPTNDIGLIQPPAGAPIVIAVYFHA -TRSTDAQREAVIADATRLALK-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Chitinophaga sp. YR627 TaxID=1881041 RepID=A0A1I4ZSR1_9BACT ---NTRQKVNEIAATARGHVGMAMMSLESGDTM-TLNGNDHFPMQSVFKVPLAIAVLDQVD -KGKLSLDQVIHITKKELLPWSPIREKYPEGTLKLREVLAYTVSQSDNNGCDILFNLVGGT -AYVEQYIHGLGIDSMAIKANEERMASAWKVQYTNWSSPLATLQLLKGIHTGKYLSKSSND -FLLKIMKETTTGPKRLRGMLPSDAVVAHKTGSSDTAATNDAGIITLPDGSHLAIVVFVSD -TKVNEAIREGVIARMTRLFWD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A411G5Q4_PROMI --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYTPVTEKHLTDGMTVRELCSAAITMSDNTAANLLVTTIGGP -KELTAFLHNMGDHVTRHDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGKRG------------------------ ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1B1 TaxID=2080528 RepID=A0A2S5YG18_9MICO ----VSAELAALESEFDARIGVSAVDTGSGRRV-EHRSNERFGYASSLKALAVAEFLRTVP ---AAERDEVVTWTAADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRIGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGEVLSAEDRA -LLLAWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter sp. Tr-809 TaxID=2608324 RepID=UPI00142352F4 ---TLEDQIKTL-SDKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLSLDHSKTIQQKDLVTYSPVVKEYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -VGLTSFMRSIGDKVTRSDRYEPDLVINPEGDIRDTTSPNAMNTSMKKLLVGNVLSTSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSESHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus capitis TaxID=29388 RepID=UPI00071289EC -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDDTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1V0QSV5_PSEAI -----SAKLQSLEAG-QARLGVCFLDTVTGEVS-GNRIEERFAMCSTVKLAIVAACLREAD -KARLNLEEILTYSEADLLPWAPVTRKNLAKGLSISALAQAAQEMSDGVAANLLIKRLGGP -AAVTAKFREMGDSVTRLDRYEPDLGLVLSADVRDTTTPLAYAQLVRRITTGRVLSHGSRE -QLLEWMRNTVTGASRLRAGLPTEWRTGNKTGTGRTNKCNDVAITFPPSKNPIIIAAYFDS -GEKVEARHEAVLAEVGKIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. BK227 TaxID=2512162 RepID=UPI00104E6479 ------DALGALERRQGGRLGVFAVDAGSGRTL-AHRADERFMLFSTFKGVLAAAVLADVD -AGTEAFNARVSYTAADLLPASPVTRAHLDEGLTVMALCLAIMHKSDNAAANLLLARRGGP -AHLTAFVRRLGDAVTRFDRYETAAG--TPSGIRDTTTPRAIVSTVRALLLGDVLSATSRA -TLEAWMAGNEVGRSRLRATFPADWAAGDRTGTGN-GYCNDYAFARRPGKPPLLVSAYFEA -PGMTLAKQEAVLRQVGAIIV--- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum sp. B506 TaxID=137721 RepID=UPI0005B28A7F ----------------------------------------------------------TVD -EGKDRLDRRIPVTKADLLPYAPFSETRLNGTPTLAELCEAAVTLSDNVAANLLLPGVGNP -AGLTAFLRAIGDKTTRLDRNEPTMNTAIPGDPRDTTAPAAMVRSMERLLLGDALRPDSRQ -QLTGWMVANKTGDKRLRAGLPAGWRVGDKTGTGANGTANDIAILWPEGRAPLLVASYLTQ -TAEGFKQQDSIHAEVARTVAGL- ->[subseq from] class A beta-lactamase n=1 Tax=Aeromicrobium sp. zg-629 TaxID=2663859 RepID=UPI0012B57622 ---QIADRLAALEEQHDVTIGVSAVDV-QGKRV-EYRAGDRFGYASTVKAFAAATMLAEKT ---PQERAKTVRWTQADIDAYSPVTSEHPERGLTLDELAEAAVRDSDNTAMNLVLRSVGGP -EAVEKFLRTLGDDRTQLDSYEPDLNTVTPSQVANTTTPTAFATALQAAVETKAIAPRERR -TLLDWMGGNSTGDTLTRAGLPAGWEVADKSGGAG-GLRNDIGVVTGPDGQTVYLAVFTST -NDPEAEYDDVVVEEAARAVLAEy ->[subseq from] class A beta-lactamase n=1 Tax=Brachybacterium sp. YJGR34 TaxID=2059911 RepID=UPI000E0B9D36 ------AAFGDLEAEFAARLGVYAIDTGTGEVV-EHRADERFGFASTIKLFAAAELLDATT ---ESELETSIDVPE-TVLAHSPVLEEHAGGTVTLAEAIDASLVSSDNTAADFVFDQLGGP -EALEERLRAIGDDTTRVARSEPELNDIAPGDERDTSTARAFATSLRAYTVADTLAEDDRA -ALVDAMVRSTTGDALIRAGAPTGWTVGDRSGAAGYGSRNDIGIAYPPDGAPVVLVIFTDR -AAEDADFDDALLAEATQVVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_016 TaxID=1898740 RepID=UPI0008DDE5CA ---AVARTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH ---GADRDERVRWSAADATAHSPVTSEHVADGLTVAQLAEAAVRQSDNLALNLVLDRIGGP -AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAATLATVLDGQTLGRSDTA -LLEHWMSGNTTGDTLVRAGAPDGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR -NAPDTAYDDALVARSAAAVLDAf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE7AE7B ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia speluncae TaxID=419477 RepID=UPI0009FD2A22 ---ELSNSLMEIQERHNVLFGIAAYSPTGARTF-EWNAADRFALTSTFKVYAVAALLRLAE -RGEVDLNERVPILHADIVIASPTTSYRAGETLSWYDLCQAALVRSDNTAANLILRRIGGP -PAVTALARMIGDTETRLDRWEPALNEALPGDTRDTSTPAAFAGGLHRLVLGNALIPVHRR -MLTGWMRSSVTSGDRMREGLPVGWVAADKSGTGAYGTVNDAGVVWSPTGTSVVLVIFSRS -TIPMAAPSNKAVADATTAVL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas viscosa TaxID=871741 RepID=A0A1I6QFA6_9CAUL --------LSALEARNGGRLGFAAMDLARGRNL-VWRGGERFVYCSTFKSYLAAATLLRVQ -SGAERLERLIPVTRADMVLHAPTTGPAVGSTLTIERLMEATVGLSDNPAANILIRELGGI -DALRAFYRGVGDDITRVDRLEPEMNRL--DGDKDTTTPLQSMRNLVSLLVSEPLSPASKA -LLLRWMTETPTGAGRIKAGVPAGWTVAHKTGTGGYGPSNDIGVLYPPAGEPVVLAVYYHA -TPESAASNDAVIAEATRMALDAf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E2 TaxID=2080550 RepID=UPI000CE8E411 ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEEATATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVSEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia carnea TaxID=37328 RepID=UPI0009D92B6C ---DLSNTLMEIQERHDVLFGIAAYSPTGARTF-EWNAADRFALTSTFKVYAVAALLRLAE -RGEVDLNEQVPILQEDIVIASPTTSYRVGETLSWYDLCQAALVRNDNTAANLILRRIGGP -PAVTALARMLGDTETRLDRWEPALNEALPGDTRDTSTPAAFAGGLHRLVLGNALIPEHRR -MLTGWMRSSVTSGERMREGLPVGWVAADKSGTGAYGTVNDAGVVWSPTGTSVVLVIFSRS -TIPMAAPSNQAVADATTAVLE-- ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) TaxID=278992 RepID=A0AC32_STRA7 ----LSKTLRALEKSYDGRIGAVGIDLGDGRTV-AYRADERFPFNSSFKVFACAAVLDKAR -TGDGLMEQVVRWEPADMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNLLLEQIGGP -RGLTAFFRAVGDRSSRLDRPEPRLTEWEPGGVRDTTTPAAAARTFTELTTGDTLQGGDRA -RLVGWLKASVTGADRIKAGLPKDWTVGNKTGTGGHGTASDLAIVWPPGTAPLILSVYTNR -NHDNTAHDDKVIASTATALA--- ->[subseq from] Beta-lactamase n=2 Tax=Chitinophaga ginsengisoli TaxID=363837 RepID=A0A2P8FZF6_9BACT --nTVRKKIHDIAQTAHGHVGMAMMSLEDGDTI-TLNGKDRFPMQSVFKLPLALAVLDQVD -KGKFSLGQVIHIYKEDLLPWSPIREKFPEGTMKLSDILAYTVSQSDNSGCDLLFRLVGGT -AYVEKYIHSLGIDSIAIRATEEQASKAWGVQYTNWSSPVAMLQLLKGVHTGKYLSKSSND -FLLKLMTATTTGPKRMKGMLPEGAVVAHKTGTSDTAATNDVGIVTLPNGKHYGIVVFVSD -TKADTAIREGVIAQLTRLFWD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Auraticoccus sp. F435 TaxID=2656650 RepID=A0A6A9V2L4_9ACTN -------RLGELERRHDVTIGLWARNLRTGREL-AHRADSRFPICSVFKALAVAALLRGVV -PDAHVLRRPAHIPPAALLEVSPFVEQCLRDGPTVEQLCVATLQLSDNTAGNEVLARIGGP -TAVTRFARSLGDTTTRLDRWEPELNSAEPDRVTDTTSPRAVGRTVAGLLTGRSLPRRDRD -RLTGWMLGSTTSAERLRAALPPGWQLADKTGGGSYAVNNDVGVAWAPDGTPLALAVMVRS -DDPAAVREDTVVAEVGRLCV--- ->[subseq from] Beta-lactamase n=1 Tax=Enterobacteriaceae bacterium TaxID=1849603 RepID=A0A351NQD5_9ENTR -----------------------IVNADGQPIF-GYRQSERFPLTSTFKVLACAALLDRLH -KTAGSLNETVTIKPDELLSYSPITKNYVAPAITLQTLCSAAVSYSDNTAGNSILAYLGGP -DAITRFMRESGDDVTRLDRTEPTLNEATPGDARDTSTPERMASGLHTLLGTPRLTAPHRE -MLEQWMRDDKVADNLLRAALPEGWAIADKTGAGGYGSRAIIAAVYPKGAQPVYMAIYITQ -TDAEMKMSDGVIKGIGERVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium pusillum TaxID=69373 RepID=UPI0011A68EF1 ---AVAKALAALEQQYDATVGIVATDTTTGETV-SHNGDRRFGYASTLKAFAAAQFLRSVH ---GAARDERVHWTAADVTAYSPVTEQHVSDGLTYSQLAEAAVRQSDNTALNLVLKRIGGP -KGLGDALTELGDATTQVVNDEPALNTIEPGSTEDTTTPAAFTADLARVFDGHTLDASDTA -QLQDWMSGNATGDTLIRAGAPKGWTVADKSGGAG-GIRNDIARVTTTDGHEITISVLTTR -NDPAAKYDDALVAKSAAAVLQAf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A2X1C7J8_BREDI -------DLSALEARHGGRLGVSAAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDQAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPTGAPISIAIYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=UPI0009EB5DF5 ----VAAELAALETEYGATIGVLARDTSSGASI-AFGQDRRFGFASTMKAPLAGVFLDRVE ---GAARDEVVRWSAAQVEEYAPVTAERIDEGLTLAELAEAAVRQSDNLAFNLVLERLGGP -AALDAALAELGDETTEVVNLEPALNTIEPGSTDDTTTAAALAGTLEALLLGPTLDADDRT -LLLDWMSGNATGDTLIRAGAPEGWVVADKSGGAG-AIRNDVALVTRPDGAPIVIAVLTQR -DDPEAERDDSLVARAAEIALDAf ->[subseq from] Beta-lactamase Toho-1 n=2 Tax=Altererythrobacter namhicola TaxID=645517 RepID=A0A1C7DBC0_9SPHN ----VAVEIAALEQTSGGTLGACLLDTASGALL-GHRLDERFGHCSSFKTSLAAMVLAGAD -NGTLDLSEQMAWEETAMLGNSPFTMDRLGTGATLAELARAVQVASDNTAANVLLGRLGGP -EAVTAFWRELGDETSRLDRTEPQLNNAPAGDPRDTTTPRAMAQTLAKIATGDVLAPESRA -TLLGWMAETTTGTRRIRAGLPEVWQAANKTGTSLGSLYVDIAVLTPSGATPLVLTGYFRA -NETHQPEGEAVLARLGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis witflariensis TaxID=173675 RepID=A0A246K5M3_9SPHN ------KQIAEIEKRSGGRLGVAVTDSQGDLLF-GHRADERFAMCSTFKLLLAGQVLERAA --DGVSLRTPLSFTRADLIAHSPGTEKLLGADQRLGAAARDAVVLSDNAAANLILTQMGGP -AVFTAALRGAGDDVTRLDRIEPELNENAPGDPRDTSSPAAMAKSAAAYVYGNRLTGDYRK -QLRDWLIESETGLARIRGGLPTGWLSGDKTGTCGT-AYNDVAFVEEPGGAKYMIAVYLDR -PAVKGDAANAAIADVARAVAR-- ->[subseq from] Class A beta-lactamase n=2 Tax=Hyphomonadaceae TaxID=69657 RepID=A0A2D7IYK3_9RHOB ------TAIGYAESQNGGRFGVSAVNLATGETI-THRGDERFAMCSSFKWLLAALVLQRVQ -AGDEALDRVIEFTEADMVSHAPVTQSALADGLSVEALCRGTVQTSDNPAANLLLRTLGGP -EGFTAMLRADGETTTRLDRWEPELNENAEGDPRDTTTPNAMVSLMGFYLFGAGLSAEYQT -LLKDWMIGASTGLTRLRAGIDAPWASGDKTGTSSNNQSNDVAFAYKTAADPILISSYLNV -ADPMSEETNALHATIGRQIM--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WTV1_9BACT --nELRDRIEQISQAARGRVGVTATVLETGESV-TLNGDRQFPMQSVYKFPIGMAVLAQVD -RGKLKLDQKIRVEARDFVSHSPIRDENPQGLLSLAELLKYMVSESDGTACDVLLKLVGGP -EVVTQYLRDLGVNGIVVANTEKEIGQDKAVQYRNYASPNAAVVLLQALHEGQGLSESSQA -LLRKLMTQTPTGLQRIKGLLPDGTVVAHKTGTSRTAATNDVGLVTLPNGRHMAIAVFVSD -SGANNATREGVIAKVTKAAWDEw ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A1Z3LZR5_BREDI ------LDLSALEARHGGRLGVSAAT--EGRRA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPADWTVAHKTGTGGYGPVNDIGLILPPNVAPIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] Beta-lactamase n=2 Tax=Frigoribacterium faeni TaxID=145483 RepID=A0A511A7R5_9MICO ----LDAPLAALEAEYDALVGVSALDTGTGRRV-DHRADERFGYASTIKAFLAAQFLHDVP ---AAERDERVTWTQSDVDAYSPVTSEHVDDGLTLAELVDASVRFSDNTATNLVFDRLGGP -TELDTSLAALGDETTEVVNVEPALNDVEPDGTDDTSTAAAFTADVTTILTSDVLADSDRA -SWVDLLTGNATGDTLIRAGAPEGWTVADKSGGAGP-IRNDVAIVTPPGRDPIVLTILTTK -NDPDAAYDDALVADAARVVLD-- ->[subseq from] Uncharacterized protein n=1 Tax='Candidatus Kapabacteria' thiocyanatum TaxID=1895771 RepID=A0A1M3KZ26_9BACT ---EARRQIAKIIQSSNAKVGVSVLGLEDRDTL-AFDGKGHYPMQSVYKFPLAVAVLHEVD -RGKLSLDMKIHVRKKDLLPWSPMRDKYPKGELTLSEILRYTVSQSDNNGCDILFRMLGGP -AKVEAYIRSLGITGMAFAATEEEMHERPKTQFSNWCEPEAMVKLLDMFHGGRILSESSRK -FLWNAMAETSTGPDRIKGLLPPGTTVAHKTGSSGRNALNDVGIVVLPKNRHVAIVVYVSD -SHEDNDTLENVIARISKIVWDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Siphonobacter sp. BAB-5385 TaxID=1864822 RepID=A0A261Q5Y5_9BACT --kSLQNQIEQLIQPKKATVGVSIYDFASKQTL-LIHGDKHLPMQSVYKFHVALAVLKEVD -KGRFKLEQKLHVKKSDLVPHSPMGEDHPNGELPLSEIIRYMVSESDGSACDYLFRLLGGP -TQVNAFIHQLGIKEVAIRETEETMQANWDVQYTNWTTPAAMLDLLKLFYQQKILSKRSHD -FLWKVMTETVTGENRLKKLLPTGTLVIHKTGTSGMGAVNDVGFIALPNGKHIAISVFVTN -TSEGIEKNEQIIADIAKLAYDHf ->[subseq from] Beta-lactamase class A n=2 Tax=Pelomonas saccharophila TaxID=304 RepID=A0A4R3ULZ2_PELSC -------DFAALERRVQGRLGLFAIDTGSGRTL-AHRADERFATCSTFKILLAARVAQGVE -RGRWQWRDEIALHKSDRVPYSPVFDRLLPRGATLAELVTGILVESDNPCANLLLRHCDTP -VGFTTWLREQGDEVTRLDRHETELNENSPGDPRDTSTPRAFAKTLQRLLVGEGLARDSQA -RLRADLQASRTGLARLRAGVPEGWRVLDKTGTGKRGAINDVALVYPPDGGPWVIAALQSD -SRAATDELSEVHADAMRLIVKAw ->[subseq from] class A beta-lactamase n=1 Tax=alpha proteobacterium L41A TaxID=1229204 RepID=UPI00037D96A5 --------LSDLEARNGGRLGFVVQDAATGRKL-VWRGEERFVYCSTFKMYLAAATLLRVQ -AGQERLDRRIPITTADMIDHAPVTEPAVGDSLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRGIGDVSTRSDRFEPEMNRL--DGDKDTILPSQSVANLQRLFLDPALTTVSRA -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGGYGPTNDIGLLYPPSGQPVIVAAYYHA -TRATDDANAAVIAEATRRAL--- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000734A824 ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNNKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNIYDPKSNRDTSTPQAFGKTLNKLINDGRLSKENKA -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4V2ABD3_9BURK ------------------------------------------------------------- ---------------ADLVSYSPVTQKHAGDGMTVAGLCAAALQYSDNTAGNLLIRLLGGI -DAVTAYARGIGDSAFRLDRWETELNTAIPGDPRDTTTPAAMATSVQRLALGDALGAPQRA -QFVAWLRGNTTGATRIRAGVPADWELGDKTGTGDYGTTNDVAVLWPPGRPPLVMAIYFAQ -PASDAAARNDVLASAARIV---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1B2ZDJ9_KLEPN -----------------------------------------------SKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGA -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGNALADTQRA -QLVTWLKGNTTGSASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLILV----- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2762 TaxID=2609254 RepID=UPI00132EB15E ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A4 TaxID=2080522 RepID=UPI000CE8AEB8 ----VAAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf294 TaxID=1736326 RepID=A0A0Q5AV24_9MICO ----VSAELAALESEFDARIGVSAVDTASDRLV-SHRQDERFGYASSIKVLAAAQFLRAVP ---AAERDEIVTWTAADVEAYSPVTSESIGEGLPLSELAEAAVRRSDNTALNLVLARLGGP -SALDRGLEDLGDTTTEVVDDEPALNTIEPGSTANTTTPAAFTAALRAVTLGTALPGEDRA -LLLDWMSGNATGDALVRAGAPSGWVVADKSGGAG-GIRNDVAVVTPPGRDPIVLSILTAR -NDPDAAYDDALVARSAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces ambofaciens TaxID=1889 RepID=UPI0007B4242E ----LSKTLRALEKSYDGRIGAVGIDLGDGRTV-AYRADERFPFNSSFKVFACAAVLDKAR -TGDGLMEQVVRWEPADMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNLLLEQIGGP -RGLTAFLRAAGDRSSRLDRPEPRLTEWEPGGVRDTTTPAAAARTFTELTTGDTLQGGDRA -RLVGWLKASVTGADRIKAGLPKDWTVGNKTGTGGHGTASDLAIVWPPGTAPLILSVYTNR -NHDNTAHEDKVIASTATALA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium SYSU XM002 TaxID=2605990 RepID=UPI00135A4481 ---ALTKQLAAITAPLVGRVGVAAKLIGSNNVI-ALNGDELFPMASVYKVPAAVAALRKVD -AGQLSLNQLVEIKPDDLSAGDNVIATHPGIQLSVANLIEAMITESDNTATDMVFDVAGGP -SNITSTMRSLGITGMRIDRNTKELMTAYEADPRDQSTPLAMLELLMQIEDAKATSRSSRD -FLLASMSRTRTGPGRLKGLLPRGTPVAHKTGTSS-GVANDVGYITLPDGRRFIVVVFTKS -SSTPRPDRDRAIAEVARTLFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. BH-2-1-1 TaxID=1905847 RepID=UPI00089DF594 ---AVDRTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH ---GADRDERVRWSAADATAHSPVTSEHVADGLTVAQLAEAAVRQSDNLALNLVLDRIGGP -AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAATLATVLDGQTLGRSDTA -LLEHWMSGNATGDTLVRAGAPEGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR -NAPDTAYDDALVARSAAAVLDAf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0005DB91DD ------------------------------------------------------------- ----------IHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=6 Tax=Pseudomonas TaxID=286 RepID=E9N9H5_PSEAI ---TASDALAALELRNGGRLGVFALDAGSGRSL-GWREDERFGMCSTFKLLLAATVLDAAR -QGRLDGTAPIHFSDDDLVPHSPVLREHLALGLTAPELARATQLTSDNAAANLLIRKLGGP -EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE -RLREWMVETGTGLARLRAATPPHWQAGDKTGSAIPNKTHDVAVFWPPGRAPVIVAAYYES -DAHHRAQDEAVLAQVGRIAV--- ->[subseq from] Beta-lactamase n=2 Tax=Pseudarthrobacter chlorophenolicus TaxID=85085 RepID=B8HGJ3_PSECP --qRLDTALSGLESAHGLTIGVSAGRLGQRPAY-AYRGENTFPMCSLFKTLAVARLLRDHA -YDDGFWQRRISFRKNQIVRDSVICAADKDRNMSVEELADAALRFSDNTAGNLLLELIGGP -PEIGAYARSLGALSTRLDRWEPELNEALPGDVRDTSTPSDIHTLYEALLLGDALDTLGQA -RLRGWMLRNATSGERLRAAVPPGAELADKTGAGSYGVVNDAGVVWPEDGPPLTLAVMTRT -SRPDAVNNNAVVARVGQLVF--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas subvibrioides TaxID=74313 RepID=A0A258FRL9_9CAUL --------LSALETREGGRLGFAAKDMQTGRIL-TWRGEERFVYCSTFKMFLAAATLMRVQ -AGEERLDRMIPITRADMINHAPVTEPAIGGSLSVEALMKGTVEVSDNPAANLLLKAMGGL -EPMQAFYRGIGDATTRVDRFEPEMNRL--DGDKDTILPLQSIANIERLLVDTPLSEASKA -LLLKWMVDSPTGTARIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA -AG-DDPKNEAVIAEATQAALA-- ->[subseq from] class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf172 TaxID=1736285 RepID=UPI0009E8C170 ---DASAELTALEAEFDARVGVSALDTGSGATL-VHRQEERLGYASTIKVFAAAAFLHDVP ---VDQRDEVVTWTAADVAAYTPVTSQYVDGGMSLVALAEAAVRTSNNLALNLVLDRIGGP -AGLDRALEQLGDTTTEVVADEPALNTIEPGSTDDTTTAAAFTADLAALATGDHLAAADRA -TLLDWMSGNTTGDALIRAGAPDGWTVADKSGGAG-GIRNDVAVVTPPGRDPIVVTILTER -NDPDAAYDDALVARVASVVLA-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter boissieri TaxID=1219383 RepID=A0A1G6H2V6_9GAMM ----------DLLSKKGWQIGVSILDMD-KTVV-SINGDQRFPLNSTVKAIACANVLSKVD -ANKLTLDTSKTITKDSLVVYSPVVKNYVNKKLTLKEACQIANAYSDNTAANFIISEGGGP -EGLTAFMKSMGDDITRSDRYEPDLTVNPEGDIQDTTSANAINLSLKKLLTGHVLSEYSKE -QLKQWMMGNKVADNMLRAVLPPNWKIADRTGASDYGIRGLIAMVWSDNHTPVFISIYVRK -NGSSVDERSKVIKQLSEHVVKEy ->[subseq from] Beta-lactamase n=1 Tax=Glycocaulis sp. ZYF765 TaxID=2518983 RepID=A0A550K9M2_9RHOB ---AMEARIAALAELSGGRMGVMAFDLAGGEPV-SLNPDEPFPMASTFKIAVAAAVLARVD -AGELALGDMIEIDPDSHVMSEVIADRFIHPGLSVANLIELTITQSDNTATDVLTDLAGGP -EAVTAWLSAQGIEGQRIDRDTASLLRPFDTDPRDTSTPRAMAELLARIARGQALSETGTD -FLMGALSRTRTGAGRLRGLLPEGTPVAHKTGTIG-GTVNDAGIITLPDGRRIVVVAFVKQ -SDAPMAARERAIAEIARTLHDGf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. H33E-04 TaxID=2703787 RepID=A0A6B9ZJV7_9BACT ---NTRKYIHETTAAAQGHVGMAMLTLQGKDTM-SFNGNDRFPMQSVFKVPLALAVLDQVD -KGKLKLDQIIHIRKEELLPWSPIKKKYPDGTMPLSELLAYTVSQSDNNGCDILFRLVGGT -DYVDRYVHSIGIDSISIKATEEGMAQAWNVQYTNWATPVAILHMLVGIEKGSYLSKSSND -FLLKIMRETTTGPGRMRGLLPKDAIVAHKTGTSDTAATNDAGIVTLPNGKKYAIVVFVSD -AKADEATRDGVIAKLTRLFWD-- ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1N4A3_9CYAN --nKLRDLIEQISHAAQGRVGMTATVVETGESV-SLNGDRRFPMQSVYKFPIAMAVLAQVD -QGNLKLDQKIRVAASDIVRDSRILEKNSQGKFRLAELLKYMVSESDSTACDVLLRLIGKP -QRVTEYLRNLDVNDIVVANTENEIQKDRALQYRNYATPDAAVNLLRAFHKGRGLSKSTQA -LLRQWMIETSTGPNRIKGLLPKGTVVAHKTGTSATAATNDVGIVTLPNGQHLAIAVFVSD -SQATNAIREEVIAKLAKAAWDEw ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WLK9_9BACT --eALRKRMEEITQTAKGKVGVAVLGIEDRDTL-SVFGKDRFPMQSVYKFPVAIAVLHQVD -QRKLSLQQKIHLRPEDLLPWSPLREKYPQGNIPLSEVLLNTVALSDNNGCDVLFRLLGGP -PKVDAYIRSLGVRGMAIAATEEQMHQEEQVQYTNWSEPTAMLRLLDVFYARKALSPASTD -FLWKVMVETSTGPRRMKGLLPPGTIVAHKTGSSGTAATNDVGIVTLPNGKHVALVVFVSD -ASADEATREGVIAQITKAVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus C0673 TaxID=1413510 RepID=A0A033UR43_STAAU ---ATTQDLKKVEDKYDANVGVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKSNKDTSTPKAFGKTLNKLINDGRLSKENKA -FLIDLMINSKSGDTLIKKGAPKNFKVADKSGQATYASRNDIAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_70_10 TaxID=1801945 RepID=A0A1G2WPP5_9CAUL --------------ADNARFGAAMINLESGELW-AFNGSDRFPMMSVFKAPLGAAVLAEVD -AGRLDLDETITLTDEDLSPFSPIADAYPGRRYTVGQLLELAVGQSDNTAADVLMRRIGGP -GVVTAWLRAHRIDDMRVDRYERQMQPAYMRDPRDTTTPRAALLFLSKLSAGELLSEASTE -RLLTLMSETTTGADRLKAGLPEGARLAHKTGTARTDATNDMGIITLPDGRRYAVAVFLSG -SPLDGESREAVIADFARLAVR-- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3WZV9_9MICO --qKVSGELESLEEDFKARIGVSAVDTGNGTSF-DYRSDERFGFASTLKVFAVAELLARTT ---SADLDEQVTWTQTDVDEWTPVTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP -QGLDAALEDAGDPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDPDRLPEDDRE -VLLEWMSDNETGDPLIRAGAPKGWTVKDKSGHSD-GIQNDIAVVYPPNEDPIIITVLTQS -DNPDSEDGPTLVAAAAEAVFDSf ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium citreum TaxID=2036 RepID=A0A542FN41_9MICO ----TRQAFADLERRDGARVGVVAVDTGTGRSL-GYRADERFAFASTNKVQIAAAVLAASS ---PADLDEVVHYDRGDLLSHAPVTTPAVDTGLTVRQLVDAAIRQSDNTAANLLVERVGGV -AGVTRWLRGLGDTTTDVSRTEPDLNTAVPGDRRDTTTAAQSAADLRAVLLGDALDADDRS -LLRDSMLGTTTGASTIRAGVDPSWTVADKTGTASYGVRNDVAVVTPP------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Amantichitinum ursilacus TaxID=857265 RepID=UPI0013793255 ----AARQLAQIETTAGGRLGVTALDTGSGKWL-TYRPDERFPLAGAFTPLLAAAVLARVE -KDQEQLSRPILFTAADLQPWAPIARTRLKAGMTVADLCAAAIQFDDHAAINLLLNSVGGP -TQLTNWLRTQGDDISEIDRFEPELTSAIKGDVRDSSTPAMMLKMLNRFLLSDALAIESRA -QLQAWLVGNGNATTRIRAGLPPEWRVGNATGNGENGTTNDLAIIWPPPRAPILLTVWLTD -SKATGAVRDAALKEVARVVFA-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2804 TaxID=2609257 RepID=UPI00132F280B ----VSADLTALEAEFDARIGVSAVDTGSGRQV-AHRRDERFGYASSIKALAAAEFLHAVP ---AAERGDVVTWTAADVEAYSPVTGESTATGLPLARLAEVAVRQSDNTALNLVLDRLGGP -TALDRALEELGDTTTDVVDEEPRLNTVVPGSTANTTTPAAVTADLTAVALGERLPVEDRA -LLLDWMSGNATGDALIRAGAPEGWSVADKSGGAG-GIRNDVAVVTPPGRAPIVLSVLTAR -NDPDTAYDDALVARAAAIVL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A410NWQ6_BREDI -------DLSGLEARHGGRLGVSVAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTELAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAIYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NP160 TaxID=2586637 RepID=A0A5C4X8Y6_9ACTN -----AGQLTALEESSDSRIGLFAVDTATGRFV-AHRAEERFAFASTGKVLTAAAVLEATD ---DSELDAPTPVEPDDVVPHSPVTESRAGAAISLREAAEAAVTVSDNTAQNIMLEHLGGP -AGLEAVLRGAGDATTDPARYEPELNEVFSGDTRDTTTPRAMTASLRAYLVDGRLSPSDRD -ELVSWMEASTTGQDLVRAAVPAGWVVADKSGTPTSGGRNDVALVWPPGQAPWVITVFTDR -PGADAASVSGLVASATAAAVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9U9_SHIFL -------------------------------------------MMSTYKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLIENSPVTEKHLTDGMTVRELCSAAITMSNNTAANLLLTTIGGP -KEQTAFLHNMGDHVSRRDGWGPELNEARPNDERDGRMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGGDGKASRIVVICTTG -GQATMDERNRQIAEIGASLS--- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. Root1423 TaxID=1736462 RepID=A0A0Q7SMG7_9CAUL --------VSGLETRNGGRLGFVALDTATGRSL-GWRATERFVYCSTFKMYLAAATFVRIQ -DGRETADRMIPISRADMVNHAPVTEPAIGSSLSVGRLMQAVVEVSDNPAANLLLKANGGI -AAMQNFYRSIGDDSTRADRFEPEMNRL--DGDKDTIQPAQSVTNLQRLFLNSPLTAGSQA -RLLRWMVDSPTGADRLKAGVPAGWRVAHKTGTGGYGPTNDIGLLYPPNGKPVIVAAYYHA -TSSSAAANDAVIADAARLALK-- ->[subseq from] Beta-lactamase n=1 Tax=Luteipulveratus halotolerans TaxID=1631356 RepID=A0A0L6CMT1_9MICO ----------PIAQKHAVRLGVYAVDTGSRREV-RFHEDERFAYASTFKALASGLVLKKSG ---LAGLETAVAISAADLRPASPVSSRYVGKTMTMREIIDAAVRFSDNTAGNKLLTALGGP -AGFGTSLQALGDHVTRPSRYEVELSDGVPGDERDTSTARQLATDLRALLVDDVLPSPERA -FLRDTMWRNTTGDTTIRAGVPKGWTVADKTGTASYGGRNDIAVIWPPDREPVVIAVLSTR -DTQGSKGVDAVIAESTREVL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE80907 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPASFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPRRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. OK723 TaxID=2135605 RepID=A0A4R7BYA3_9BACT --qTLRQQIAAIAGNISGKVGVYARVLETNDTV-SFNHDERFPMQSVYKFPVAMAILKQVD -AGKIRLDQPIKIQKADLTTHSPIREKYPEGNLTVKELLDYNICESDGSACDIFFKLLGGP -ANVNRYIHGLGVKQINIATTEEAQKEQPMVQYKNWCTPLAMTQLLEKFYTTSALSDSSRS -YLLHLMTTSGPGARRLKGLLPPGTVVAHKTGTAWTAAHNDVGIITLPNGNHIAITVFVSD -AKATEQERDATIAKITKAVWDAy ->[subseq from] Beta-lactamase n=1 Tax=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) TaxID=929556 RepID=H8KP67_SOLCM ----FKDQIDQIAKEAKGDVGVALLNLEAGDTF-LYNETMHFPMQSVYKFPLAMAVLSQVD -AGKLTIDQKLHLTKRDLLPWSPLREKYPNANVTLMEVLKATVSESDNNGCDILFRLLGGP -KKVEKYIHGIGVKEIAIAATEEEMHTAWDVQFTNWCTPVAMQQLLSTFHKDDKLSEKSKQ -LLWDMMVDSPTGAKRIKALLPEGTVVAHKTGTSDTGAINDVGIIVLPNKHHLAITVFVAN -SKASTGIMEETIAKIAKAAYD-- ->[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Amantichitinum ursilacus TaxID=857265 RepID=A0A0N0GLR4_9NEIS ----AARQLAQIETTAGGRLGVTALDTGSGKWL-TYRPDERFPLAGAFTPLLAAAVLARVE -KDQEQLSRPILFTAADLQPWAPIARTRLKAGMTVADLCAAAIQFDDHAAINLLLNSVGGP -TQLTNWLRTQGDDISEIDRFEPELTSAIKGDVRDSSTPAMMLKMLNRFLLSDALAIESRA -QLQAWLVGNGNATTRIRAGLPPEWRVGNATGNGENGTTNDLAIIWPPPRAPILLTVWLTD -SKATGAVRDAALKEVARVVFA-- ->[subseq from] Beta-lactamase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4V6BLT4_9BACT ---IFRQEIDKIISASKSDVGVAIMGLEDKETF-LFNEGHKYPMQSVYKFPLAMAVLDQVD -KGKLSLNQKIHVTKKDLLPWSPLREKYPNGGIKISELIGYAVSNSDNNACDILFRTVGGP -EKVDQYIHGLGIKSIAIAATEEEMSKSWNVQFTNWCKPRAMLRLLDLFYKGKNLSKTSTN -FLMKTMTETTTGPNKIKGLLPKNTKVAHKTGLSGTNASNDVGIITLPNGEHVAVVIFLAH -TKLDEKSRDGVIAQISKEAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides insulae TaxID=394734 RepID=UPI00040918D3 --------VGDLEARTGARIGLSARNLRTGSGL-AHRVDERFPLCSTFKPLVAAALLSRRV -----DLDELIRYRSSDLVDYSPVTGERR--AMTVGELADAAIRYSDNTAGNLLLRRLGGP -AALTAYLRSVGDDVTRLDRWETELNEGTPGDPRDTTTPRALAATYHRLLVGSVLPSRDRW -VLTGWMQSNTTSVAKFRAGLPTGWWCADKTGGGAYGTQNDAGLITAPDGTRIGFTILTRA -SMPDAVGDPTLMRSLAEL----- ->[subseq from] Beta-lactamase n=2 Tax=Chitinophaga niastensis TaxID=536980 RepID=A0A2P8HPT6_9BACT --qTLRQQIAAISKNIPAKVGVYAMVLETGDTV-SYNRDQQFPMQSVYKFPIAMAILDQVD -KKKFTLDQPVMVNKSDIMPVSPIREKYPVGNIPLRELLQYNISASDGTACDVLLRLLGGT -TNANTYVRQLGVKQMTIATTEKEQQVDEMVQYRNWSTPAAMTALLTIFYEGQVLSDSSNA -LLLDLMITSGPGAKRIKGLLPPGTVVAHKTGTSGTRATNDAGIITLPNGHHLAIAIFVAD -AKADQDEREATIAKITKAAWDHw ->[subseq from] Beta-lactamase n=2 Tax=Listeria cornellensis TaxID=1494961 RepID=W7C5H9_9LIST ---KANAELKKLEEKYGATLGIYAVNTANNQKI-SYNDQERFAYVSTYKAIAGGLLLKNLT ---AEQLNKRVYFSKEDLVDYSPVTEKHVESGMTVKEIINAAMTYSDNTAGNILFHQLSGP -KGYQKELAKIGDKTTQANRFEPELNEAVPGDKRDTTTPEAMAKVLSFLVTKGNMASDRFD -YFKQTLIDNTTGDKLIRAGIPEGYAVGDKTGAGSYGTRNDIAVIYPKDGKPLVWVIYSKK -SG--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Cellulomonas sp. B6 TaxID=1295626 RepID=A0A0V8TAQ5_9CELL ----------------------HALDTVTGATA-SHRADERFAFCSTVKPLAAAAVLAAR- --GVDGMDERVPVEAADLVTYSPVTEQRVGVGMTWRELVDAALRFSDNTAGNLLLAGAGGP -AALTAWLRGLGDDVTRSDRTEPDLNAFVPGDERDTSTPGALAGTYRTLVLGDALGGPERD -LLTDAMLRSTTGDALVRAAARPGWEVADKSGAGAYATRNDVAVVWTGAGAPVVLAVLSDR -ADPGAERTDAPVAEAARVVLD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WZB3_9BACT --rELQKELEQIAAAAKGRVGVQAVVIETGETV-SLNPNEHFPMQSVYKFPIGMAVLQQVD -AGKLKLEQRVRVEKSDFVRRSPVRDKNPQGVLSVGELLRFAVSESDGTASDVLLKLAGGA -EAVNGYLKQLEVTDLVVANSEKEIGQDWETQYRNWASPESAVKLLRALYDGRGLSAQSQK -LLLKLMTETPTGPKRLKGLLPVGTIVAHKTGTSGNAATNDIGIVTLPNGRHLAIAVFVSD -SPANEATREGVIAKVARAVWDKw ->[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5WB78_9PSEU ----LERQLKELEASSHKHIGAFALDTGTGRTV-GYRTDERFPSLSTFKAVEAAAILDKAR -RDPGLLERTLHWTPDKEVPDGSTVNGHGAAGMTVSELASAAVTASDNTAANLLIEQIGGP -AGLTRYYRSLNDPVSRLDHTEPALNLWQPGEEQDTTTPAAMGRDLNQISLGSALTAQDRE -ILNGWLRSSKTGGERIRAGLPKDWVVGDKTGTINYAGANDIAVAWPPSHAPLVFTVYTYG -QQGS-TIDNKVLATVASALAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1B8 TaxID=2080533 RepID=UPI000CE8371C ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESAATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0P0DX15_SPHMC ------KAIRDLEARSGGRLGIAVVD-ARGKLVsADRGHERFAMCSTFKLLLAGQVLERAA --KGVSLRTPLAFTRADLVSWSPGTEKLVGPDQQLGMAVRDAVVLSDNSAANLILKQMGGP -DVFTAALRRAGDSVTRLDRIEPELNENAPGDERDTTTPIAMATSAAGYVFGNRLGAGHRK -QLRGWMIESETGLKRIRAGLPQGWTAGDKTGTCGT-AYNDVAFVEAPDGRKYVIAIYLDR -PAVTGDDASAVIAEATRLTVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium algeriense TaxID=634784 RepID=UPI000D3BEFCD --------LAAYERETGGRIGLYAENLASGAKI-VWRAEERFV-----KASLAAFVLARVD -RGEDRVEDMVAYGAADLLDYAPVAKANLAAGMSVSDMCKAIVELSDNTCANLLLARSGGP -AALTAFWRATGDTVSRLDHSEPELNRSPPGDPHDTTTPAAMAGNLRRFLLGDVLSMGSRE -HLTEWLVGCKTGNNRLRGGLPKEWKIGDKTGNNGKDASGDIAIAWPAAGGPVLVCAYTQG -GSPTPRQFESVFAEIGRMA---- ->[subseq from] Beta-lactamase CARB-3 n=1 Tax=Photobacterium leiognathi lrivu.4.1 TaxID=1248232 RepID=A0A0U1P6R2_PHOLE -------LLRQTEQQIDGKIGVAVFDTQTNTSW-NFNGNKRFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPVTQNFVGGQMSLNSVCGAAMLMSDNYAANLALEQVGGP -QGVTKFLRMIGDKTTRLDHFEPKLNYVEKGAENDTTTPIAMMNTIKKLLTGNVLDSENKA -QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKHHQPLFIGIFISN -SKETLPELNQVVASISAKIFNKy ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00066C709F ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKNDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAK------ ->[subseq from] Beta-lactamase n=1 Tax=Bacterioplanes sanyensis TaxID=1249553 RepID=A0A222FNZ2_9GAMM --sALTQQVQTVEASIGARIGVAVLAPDGRRGW-HYQGDQRFALTSTFKTLLCAQLLNREG -----AANTMITMRQQDLVSYAPVMKTHIGETLSAAQLCGITLASSDNSAANLVLNALGGP -MALTEFLRQHGDTTTRLDRMETELNSAIPGDVRDTTTPVAMVRTLRHLLVEQGLSSSAQQ -QLRQWMINNQVADGLLRSVLPARWQIADRSGAGGHGARAITALVWPVGEQPWVLAIYIAE -TDAEFAQRNAAIVAIGEAVF--- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00066052FD --kSTNDEIKKIEKKHNANIGMYALNTKNGKAL-SFNKDKRFAYASTFKTISSAMLLEKTP ---HNKLDKKIHITKDDIVPYSPVLEKYIGKDITLHKLIEANMLYSDNTANNKIIDELGGY -KQVKNRLENLGDTTTHPSRKEPNLNLYAPKDKRDTSTPLAYGKTLNKLITDGKLSKTNKD -FLLDLMLKNKSGDTLIKDGAPSNFKVKDKSGQATYGSRNDVAFVYPKGQKPIILVIFTNK -DKKDAKPNDKTVSEVAKVVLK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Yoonia litorea TaxID=1123755 RepID=A0A1I6MDV7_9RHOB --tKLRETVASIEDTLDARVGLVIRQSGTDWSW-SHRGDERVLMTSTFKALLCGAVLARAD -AGTLDLDEALAITPSDLQDYAQVTEARVGTFMSIGDLCLATIDLSDNTAANLLIDRLGEP -GAVTDFLRSIGDEVGRLDRHEPALNTRSADGLSDTSTPDAMATSLEALLVGDALSPSSRA -QLREWMGLGGVTGSLLRAYVRDTWDVADKSGASAN-SRSLIAMVTPDAEAPYFVAIYISE -AEVGFERRNAALIALSAAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE8EE53 ----VSAELAALENEFDARIGVSAVDTGSGRRV-HHRADERFGFASSLKALAATEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPDSTEDTTTPAAFTADLAAVATGDVLSAEDRA -VLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEAEYDDALVARAAAVVL--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000BBCB5E2 -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKXHINKDDIVAYSPILEKYVGKDITLKXLIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVXKDXKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=UPI0006278A32 -------DLSALEARHGGRLGVSVAT--EGRSA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMIRHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAAIAIAVYFHA -TKSTDAQREAVIADATRHALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=UPI0009F86B45 --aELNKKLRELEKAHKTRIGAVGIDLGTGKTV-GYRPDERFPFNSMFKVFACSAVLHKAR -TGSGLMDKVIRWTPEDMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLTQIGGP -SGLTKFFRSTGDRVSRLDRPEPYLTEWEPGEVRDTTTPAASARTFTELTTGKTLHPDDRA -RLVGWLKASLTGAARIRAGLPEDWTVGDKTGTGGHGTAGDIAIVWSPGTAPMILSVLTNR -TTDDTPNDNEAIEHTATALAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 52 TaxID=2035213 RepID=A0A2G6UKL4_9FLAO --sALEQKINAITEGKKATVGVSVLGFENNFTY-SKNGDKNLPTLSVFKFHIACAVLDLVD -KGKLSLDQKIFFKKEDMLEWSPIRKKYPDANLSLSEVLDYTVALSDNNGCDMLLRLIGGT -QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVQVLKKFYDGKLLSKKSTH -YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN -STESDAVNCRMVSDISKAVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0009A2356D ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMGGD--------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. KC345 TaxID=2530371 RepID=A0A4R4S6U0_9ACTN ----LNRTLQELEKSYDGRIGAMGIDLGTGRKV-GYRAGERFPFNSMFKVFACAAVLGKAR -TEPGLMDKVLRWKPADMAGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNTLLKQIGGP -RGLTEFFRATGDRTSRLDRPEPWLTEWEPGEVRDTTTPAAAARTFTELTTGETLHHRDRT -RLVGWLKASLTGATRIRAGLPKDWTVGDKTGTGGHGTANDVAIVWVPGSAPMILSVFTNR -NADDTAHDDKVIASTATALAK-- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium piscicola TaxID=1378299 RepID=A0A1T5HYY1_9GAMM ---NLEQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ -QNTLSLTQKIDVTKAGLINWNPITQNFVGGQMSLQSVCGAAMLMSDNYAANLALELIGGP -QGLTTFLRTIGDNNTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA -QLQLWMTNNMVSDGLARAVLPQGWNIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN -SKKTLPELNKVMVAISEKIFHQy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9S2_SHIFL -------------------------------------------MMSTLKVLLCDAVLSRVD -AEQEQLARRIHYSQNDLVEPSPVTEKHLTDGMTVREPCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDNVNRLDRWGPELNEAIPNDERDTTMPAAMETTLSKLLTGELLTLASRQ -QSIDWMEADTVAGPLLRSALPAGWFIADKSGAGERGSRGIMAALGPDGKPSRIGVIYTTG -SQATKDERNRQIAEKGALL---- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sandarakinum TaxID=629680 RepID=A0A1H1V5Z8_9MICO -----TAELKGIEGEYDARVGVHAVDTGDGSTI-EHRSDERFGFASTIKSLAVAELLATTS ---PDDLDEQVTWSKEDVDKYAPVTKKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIGGP -QGLDTALEDLGDPVTEVVDREPELNVIDHDSTDNTTTPAAFSSDLTALLDPEHLSDEDRK -VLLEWMSGNATGDPLIRAGAPDGWKVADKSGHSD-ALRNDVAIVFPPERDPIIIAIMTEH -HDPNSKSDAALIEDTARAVLGEf ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=A0A0E3YZD1_9GAMM ---------RTLEVG-PARLGVCFLDTATGEAS-GNRIEEYFALCSTFKLALVSAYLREAD -QGRINLDEVLVYTEADLLPWAPVTRKNLAKGLSIAELAQAAQEMSDGAAANLLVRRLGGP -AAVTAKIREMGDIVTRLDRYEPDLGLVLSADLRDTTSPLAMAQLVRRITTGDILQRGSRE -RLLHWMQNTKTGFNRLRAGLPAEWRSGNKTGTGRTNKCNDIAITFPPSRSPIIIATYFDS -GEQTEARHEAVLAEVGRIAAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_013 TaxID=1898739 RepID=UPI0008DCC051 ---AVARTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH ---GADRDERVRWSAADATAHSPVTSAHVADGLTVAQLAEAAVRQSDNLALNLVLDRIGGP -AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAATLATVLDGQTLGRSDTA -LLEHWMSGNATGDTLVRAGAPEGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR -NAPDTAYDDALVARSAAAVLDAf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured soil bacterium TaxID=164851 RepID=M4Q6F4_9BACT -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEG---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI001326EBF1 ----LNDTLRKLEKSYHGRIGAVGIDLGTGKTV-GYRAGERFPFNSMFKVFACSAVLHKAR -TSPGLMDKVVHWTPGEMAENSPETTEYTDTGMTPAQLCRAGITKSDGFAGNQLLKQIGGP -PGLTAFFRSLGDRVSRLDRPEPRLTEWEPGDERDTTTPAAAARTFAELTAGTGLHPSDRA -RVVAWLKASLTGATRIRAGLPKDWTVGDKTGTGGHGTANDIAIVWPPRSAPLILSVLTNR -ATDGVPHDDKVIASTATALAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium epidermidis TaxID=1698 RepID=UPI000785456C --qKVEDQLKKLEARYDARVGVSAVDTESGESV-DHRADERFGFASSLKVFAVAELLDRTT ---PKELEKNVTWTQADVDEWTPVTEEHVDDGLPLEDVAESGLRVSDNLAMNIVLDELGGP -EALDDAMEKDGDSTTEVTDEEPELNDVEEGDTDNTTTPAAFTANLQDLLDAKRLSDDDRK -VLFDWMSANETGDPLIRAGAPDGWVVRDKSGHSD-AIQNDIAVVTPPDRKPIVLSVMTET -DDPESEDGPALVAAVAEVVLNEf ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium sp. NCIMB 13483 TaxID=2022103 RepID=UPI000D1601F4 ---NLEQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ -QNTLSLTQKIDVTKAGLINWNPITQNFVGGQMSLQSVCGAAMLMSDNYAANLALELIGGP -QGLTTFLRTIGDNNTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA -QLQLWMTNNMVSDGLARAVLPQGWNIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN -SKKTLPELNKVMVAISEKIFHKy ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium marinum TaxID=418643 RepID=UPI001438B5E1 ---EVTADLTSIEDEYDARVGVHAMDTGDGSFV-EHRSDERFGFASTIKSLAVAELLDTTS ---AEQLDEQVTWTEDDVEDYAPVTKKHLGDGLPLEKVAEAAIRVSDNAAANIVFDHIDGP -AGLDSALEDLGDPTTEVIDREPELNVIDHDSTDNTTTPAAFSGDLAALLDSENLSADDRE -LLIDWMSGNATGDPLIRAGAPEGWEVADKSGHAD-ALRNDVAIVFPPKRDPIVIAIMTEH -HDPNSESDAALIEDTARAVLSAf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI001299529A ---ATTQDLKKVEDKYDANIGVYALNTVTDGEI-TFNEDKRFAYASTFKALSSAMLLEKTP ---HNKLNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A3 TaxID=2080521 RepID=UPI000CE8EF32 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVRSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519HPN3_9CAUL --------LSALERANGGRLGFVAHDVGSGRRL-AWRGDERFVYCSTFKMYLAAATFLRVQ -AGDERLDRMIPVTAADMINHAPVTEPAIGGALSVEALMKGTVEVSDNPAANLLLKALGGL -EAMQAFYRSLGDDSTTVNRFEPTMNRL--DGDKDTITPSRSAANLKRLLVDTPLSAQHKA -TLLRWMTDTPTGPGRIKAGLPAGWTTAHKTGTGGYGPTNDIGVLYPPTGAPVIVAAYYHA -ATEPADRNEAVIAAASRQA---- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. MCBA15_009 TaxID=1898737 RepID=A0A1S2HWG2_9MICO ---RVDRALAALEQRYDATVGVVATDTGTGATV-SYRADRRFGYASTIKVLAAAAFLRSVP ---VAERSAVVHWTAADVAAYSPVTEQHVADGLPSDEVAEAAVRMSDNTALNVLLDRIGGP -AALDAALADLGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFAAVLARVLDGRTLGRADTA -LLTDWMSGNATGDALVRAGAPDGRVVADKSGGAGP-IRNDVARVTRPDGDPVVIAVLTTR -NDPDEPYDDALVAESARVAL--- ->[subseq from] Beta-lactamase n=2 Tax=Brevibacterium linens TaxID=1703 RepID=A0A0B9ANZ6_BRELN -hqRLEKQLKKLEDRYDARVGVSAFDTESGESV-DHRADERFGFASSLKAFAVAELLDRTT ---PKELEKNVTWTQADVDEWTPVTDKHVDDGLPLEDVAESALRVSDNLAMNIVLDELGGP -EALDDAMEKDGDTTTEVTDEEPELNDVEEGSTDNTTTPAAFTANLQGLLDAKRLSDDDRK -VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAMVTPPDRKPIVLSVMTET -DDPESEDGPAMVAAAAEAVLTEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. YR583 TaxID=1881047 RepID=A0A1H6GC83_9SPHN -----AKAIRDLERRSGGRLGIAVVD-GGGRLVsAGRGHERFAMCSTFKLLLAGQLLERAA --KGVSLRTPLAFTRADLVSYSPGTERLLGPDQRLGLAARDAVVLSDNTAANLILTQIGGP -SAFTAALRRAGDSVTRLDRNEPELNENALGDERDTTSPIAMATSAASYVYGNRLQPEYRK -QLRGWMIESQTGLKRIRAGLPQGWIAGDKTGSCGN-AYNDVAFVETPGGRKYVIAVYLDR -PAVKGDAASAIIAEATRITV--- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter sp. CIP 110321 TaxID=1217699 RepID=R9B5T3_9GAMM -----EGQIKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLTLDHSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -VGLTSFMRSIGDEVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLMGNVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK -SETSLDERSEVIKLLSDHIVK-- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium leiognathi TaxID=553611 RepID=UPI000D153AA1 -------LLRQTEQQIDGKIGVAVFDTQTNTSW-NFNGNKRFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPVTQNFVGGQMSLNSVCGAAMLMSDNYAANLALEQVGGP -QGVTKFLRMIGDKTTRLDHFEPKLNYVEKGAENDTTTPIAMMNTIKKLLTGNVLDSENKA -QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKHHQPLFIGIFISN -SRETLPELNQVVASISAKIFNKy ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A1Q4P568_SERMA ---TLQDQVKQYEKE-GWKVGLSILS-SDGKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAISSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPVNDLRDTTTPDAMSKSIKKILTGEVLSDSSKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSEVIRTLGSHIFDEy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1U7AE41_9BACT ------DTVGQLETEVGGRIGVVLRHTGSDWAV-EHREDERFPMASTFKALLCGAVLSRVD -RGEESLDDLVTYKATELVSYSPVTKNHVASGMSVGQLCEATVTMSDNSAANLLLKRVDGP -EGLTRFLRGLGDRVTRLDRNEPAMNEARRGDPRDTTSPSAVLKTLDRLLFEGVLLPSSRA -QLQQWMVDDKVADVLIRKHLPKGWRIADK------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1B5 TaxID=2080530 RepID=UPI000CE90FDA ----VSAELAALESEFDARIGVSAVDTGSGRRI-EHRSNERFGYASSLKALAVAEFLRTAP ---AAERDEVVTWTAADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRIGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIEDTTTPAAFTADLAAVATGEVLSAEDRA -LLLAWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILTAR -NDPKADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE88DD4 ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAESAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter gyllenbergii NIPH 230 TaxID=1217658 RepID=V2WAG0_9GAMM -----EGQIKTL-SEKGWQIGVSILDMD-DKLI-SINGDKRFPLDSTVKALACANVLAKVD -AKKLTLDYSKTIQQKDLVTYSPVVKDYVNKKLTIKQACEITTAYSDNTAANFAIEAGGGP -VGLTSFMRSIGDEVTRSDRYEPDLVINPEDDIRDTTTPNAMNASMKKLLTGNVLSKSSKE -QLKEWMIGNKVADNMLRAALPKGWKIADRTGASDYGIRGLTSMVWSETHAPVFISIYVRK -SETSLVERSEVIKLLSDHIVKEy ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3C0W3U9_9CAUL -------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTQPAVGSTLTIAQLMKGAVEVSDNPAANILIREMGGL -DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALESAFKR -LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGQAIAIAVYFHA -TKSTDAQREAVVADATRQALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD1C350 ------------EKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVS ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus halophilus TaxID=226505 RepID=A0A1N6H3X3_9BACT --qQISQKIERLSEKLAGRIGVAAQEIGSKEMI-TINGDEQFVMASTYKVAIAVALLDRVD -KGELKLSDLIDVEQETMVTGDGAIANHPGIKLSVANLIEPMITLSDNTATDACLKLAGGP -EAVTKMMRSIGITDLRVDRYTSEILRFEQEDPRDQSSPNAMLQLLLAIDSGKALSAESTQ -FLLSTMSRTRTGAARLKGLLPKGTPVAHKTGTIG-GVANDVGYVTLPDGRRFAIVVFTKN -STTSEADRDRAIAEVTRTLYDFy ->[subseq from] Beta-lactamase L2 n=1 Tax=Sphingomonas sp. 8AM TaxID=2653170 RepID=A0A654CG91_9SPHN ---STEDALAALERRAGGRLGVCIVDTARGTTT-GWRQDERFTQASSFKLSLAAMILAEAD -GGRLGLGERLGWSAGDILPHSPITAASAAMTLPIRELARAAVVTSDNIAANVLLRKIGGP -ARLTAFWRAIGDRISRLDRYEPALNVTPPGTVLDTTTPAAMAATVSRIVRGDVLRPASRA -LLVEWMVAADTGRNRLRAGFPAGWHAGDKTGTGGRPIYVDLAFGGPRGRAPLIVAVYYKP -VGASAAGAEAVLAAVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. AAP58 TaxID=1523422 RepID=A0A0N1LJH5_9CAUL --------LSTLEAREGGRLGFAAKDMGTGRVL-AWRGDERFVYCSTFKMFLAAATLLRVQ -AGEERLERMIPVTRADMVSHAPVTEPAIGSSLSVEALMKGTVEVSDNPAANLLLKAMGGL -EPMQAFYRDLGDATTRVDRFEPEMNRL--DGDKDTILPLQSVANIQRLLVDTPLSADHKA -LLLKWMIDTPTGMARIKAGVPTGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA -AS-DDPKNEGVIAEATRLAL--- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter ginsenosidivorans TaxID=398053 RepID=A0A5B8UWT6_9SPHI --kELLSRIKTISAESKGIVGVSILGLESHDTL-NYNGQSRLVMHSVFKFPIAMAVLNLVD -KGKYKLDKKMKVGKGDMHPWSPMRDKYPDGALPLSEIIGYMVSQSDNTACDFLLKKIGGP -KVVEEYIHSLGVKGIAIKASEADMASAWEVQYTNWAKPADLVYLLDIFYHGKALSKQSND -FLMQAMLATTTGPHRLRGLLPKDAVIAHKTGTSPTNATNDIGIITLPNGKHLAIVVMVCN -SKADEATRDAVIAKIAKAAWDTy ->[subseq from] Beta-lactamase n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VE13_9MICO --------FEKLERQYDARVGVSAIDTATGRQV-NYRAEERFGYASTLKVFVAAEFLHDVS ---ASDRDGRVKWSESDVQAYSPVTSENIETGLTLSQLAEAAVRKSDNTAVNLLIAQLGGP -QAIDAGLTELGDSQSEVVNDEPLLNRIEPGSTDDTTTPATFRANLTSLIEGSYLEPADLA -ILTGWMSGNTTGSALIRAGAPSGWTVADKSGGAG-GIRNDIAVVTPPGRDPIILSIFTNT -LDPAAAYDDRLVAEASAAVFDE- ->[subseq from] Beta-lactamase n=2 Tax=Brevundimonas diminuta TaxID=293 RepID=L1QQB0_BREDI -------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMIAHAPVTQPAVGSTLTIAQLMKGAVEVSDNPAANILIREMGGL -DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALESAFKR -LLLEWMMASPTGLARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGAPIAIAVYFHA -TKSTDAQREAAVADATRQALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. AAP58 TaxID=1523422 RepID=UPI0006B88934 --------LSTLEAREGGRLGFAAKDMGTGRVL-AWRGDERFVYCSTFKMFLAAATLLRVQ -AGEERLERMIPVTRADMVSHAPVTEPAIGSSLSVEALMKGTVEVSDNPAANLLLKAMGGL -EPMQAFYRDLGDATTRVDRFEPEMNRL--DGDKDTILPLQSVANIQRLLVDTPLSADHKA -LLLKWMIDTPTGMARIKAGVPTGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA -AS-DDPKNEGVIAEATRLAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI00114F9A26 ---TLQDQVKQYEKE-GWKVGVSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059Q5E9_9BACT ---TVTEAAMAVEADLGGRVGTLLRAPGAAPLA-AWQADDRFPLSSTFKAPLCGAVLARVD -AGSEQMDRVIPYTAQDLVSHSPVTETRAGKGMRVADLCAATITLSDNTAANLLLDTVGGP -EGFTGFLRSIGDMTTRLDRQETALNEALPKDQRDTTTPRAMTDTLEALLFSGILSTESRT -QLESWMQQDQVAGALIRASLPEGWTIADKTGAGGHGARSIV------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis panaciterrae TaxID=363841 RepID=UPI00141FAD5A ------KALSDLEKRSGGRLGIAVVDARGKLVM-ADRGHERFAMCSTFKLLLAGQMFERAA --KGSSLGTRLAFTRADLISYSPGTEKLIGPDQRLELAARDAVVLSDNTAANLILKQAGGP -AAFTAALRRAGDKVTRLDRIEPELNENALGDERDTTSPIAMATSAASYVFGNRLRPAYRE -QLRGWMIESRTGLNRIRAGLPQGWMAGDKTGTCGN-AYNDVAFAEAPDGRKYVIAVYLDR -PTVAGDAANAVIAEATRLTVE-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X756_9BACT -------------------------------------------MCSTFKALAAALVLVRVD -EGEEKLDRRIKFSKKELVSGSPVTQARVGEPMTVAELCDAAVTRSDNTAGNLLLASFKGP -AALTAFCRTLGDDVSRLDRIETELNYDRSDDIRDTTTAAVMLENLRKLLFTDILSGGSRS -QLVAWLITSKTGDARLRAGLPKSWLVGDKTGTNGYGNANDIAVIWPPDRAPIIVTAYCEI -PSIPADERDAVIADIGRIAS--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D2XSF3_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAEXXXXXXXXXXXXXXXXXXXXXXXX -XSVTAFALQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1C1 TaxID=2080534 RepID=UPI000CE7F01D ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=A0A1I5CEG6_9SPHN --------IAAIERKHGGRLGVFVLDTGSGRTL-AHRAEERFLMCSSFKGVLAACVLARID -AGIDRLDSMIHYGRSDLLTSSPVTEAHVEVGMSVEALCGAILTQSDNAAANLLLARINGP -AALTKFARRLGDRTTRFDRTELDLNTA--SGLLDTTTPAAIVSTVRMIYLGRVLKPTTLT -VLERGMIANARGPRRLRGTLPRSWIVGDRTGTSDD-YCNDLAFARRPHAAPVVMAAYYEA -PGRTTEAREAVLREVGTRIAD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter frigoritolerans TaxID=652788 RepID=A0A562UGK9_9SPHI --tSLHDQVEQIAKPAKAIVGVSILNLETGDTV-NYNSKARLVMHSVMKFPIALTVLHLVD -SGTLKLDQMIHVTKKDMQKYSPLRDKYPKGDVSVSDLLGYMVSQSDNDACDILLRVLNGP -QTVQDFMLRSGIRGIAVRASEADMASAWELQYTNWCKPVEMNLLLDKFYTGKLLSKSSTD -FLYKLMVATTTGPKRIKGLLPEGTVVAHKTGTSPTSATNDVGIIELPNGKHLIVSIFVCN -SKDDEATRETVIAKIAKAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=A0A4P7BSZ4_9CAUL -------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFLYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMIAHAPVTAPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL -DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPVQSARNIERLILSEALESASKR -LLLEWMVASPTGQARLEAGVPSGWTVAHKTGTGGGGPVNDIGVVYPIEGAPIIIAIYFHA -TPSTDAQREAVIADAARLALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas hominis TaxID=156981 RepID=UPI001134C1DE ----VAGDLAALEESTGRRVGVYARDTGTGATV-AYRADERFGYASTLKALAVGEVLAGRP ---ASVLDEPLTVAPDDVAGHAPVTGDAAGTDLTIAALGAAAVSESDNGALNVLLRHLGGP -AALQAALAARGDTTTRVDADEPELNAFTPGGEARTSTPRALAGGLATYALGDVLDPAVRE -TYVGWLTASTTGPDAIRAGTPDGWTVGDKTGTAGYGSRNDIAVVWPPGRQPIVLAVLTDH -PDEAAEPDDAVLAAAARSVLAAy ->[subseq from] Beta-lactamase class A n=2 Tax=Novosphingobium sp. PhB57 TaxID=2485107 RepID=A0A4R3TBT5_9SPHN ---QAASDLEEIERQHGMRIGAVMRGSDGRIHF-AHRADERFRLCSTFKIFLAAEVYRQAA -TNPHLLQRPVTIRDTDRLGNSPVTARQRDGSLSAEMLCKAAVQYSDNSAANYLLDLVGGP -PAVTRLFRTLGDNISRLDRMEPALNLGAPEDFRDTTTPAAIARSLGTLLLSTVLGDHQRA -TLLGWMRNEQNGTRRIRAGVPRGWTVANKPGTNDAGAVNDIAIIRPPSGGSFVLTVYTAS -AENRVTQSESVIAAIAGMA---- ->[subseq from] Class A beta-lactamase n=1 Tax=Frigoribacterium sp. Leaf164 TaxID=1736282 RepID=A0A0Q5L9F3_9MICO ---------AALESEHGARVGLSVVDTGTGRAL-EHRGDERFLYASSLKALAAAALLDATE ---PADLDEVVTWTADDVAAYSPATSAATGTGLTLGQLAEAAVRQSDNTALNLVVEHLGGP -AALDAALAAQGDDVTDVVHGEPELNRPTAGSTADTTTPAAVRGLLARVVAGEWLGDDDRA -QLLEWMSGNATGDALVRAGAPEGWAVADKSGGAGP-VRNDVAVVTRPGGDPVVIAVLTTR -TDPAAAYDDALVAAAARAAFE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium palustre TaxID=493376 RepID=UPI00040D7069 --qSLKMQIESIIKAKNATVAVSVLDFENNKSL-DINGDKKLPMLSVFKFHIALAVLNLVD -QGELNLNQKIFIKKTDLHEWSPIREKYPAGNMSLSELLKYSVAQSDNNGTDLLLKLIGGP -GEVQNFINNTGISDFRIKADEEKMHQGYEFMYWNWTTTNASNQLLKKFFEGKLVSKKSTD -FLMQTMLETSTGANKLVALLPKGTPVAHKTGSSGKDAENDIGIVTLPSGKHYAVSAFVSD -SMESDETNTKMIAEISKLIFDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. A083 TaxID=1759083 RepID=A0A0W1IDK5_9SPHN ---SVANRIAALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK --NGVSLRTPLPFTRADLLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP -TAFTDHVQATGDLVTRLDRVEPELNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRT -MLRDWLVKSETGLARIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR -PALKGDAANAIIADVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. WO024 TaxID=2697563 RepID=UPI001423228C -hrQLDNQLKALEDRYDARVGVSAVDTADGTTV-GHRGDERFGFASTLKVFAVAELLDRTT ---PKQLKKNVTWTQDDVDEWTPVTGKHVDDGLPLTDIAEAALRVSDNAAMNIVLDEIGGP -EGLNAALENEGDATTEIVDEEPGLNVVTPGRTDNTTTPDALTADLKGLLDPRRLSTDDRD -QLLEWMSDNETGDPLIRAGAPDGWSVKDKSGHSDT-IQNDIAVVTPPGEDPIVLSVLTEA -KDPD--SGAALVAAVAEAVLDGf ->[subseq from] Beta-lactamase n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6TLW0_9BACT ---IFRQKIEKILPQAKGTVGVAIMGLEDRETF-LFNEGLKYPMQSVYKFPLAMAVLNQVD -KGKLSLNQKIHITSKDLLPWSPIREKYPKGNLKLSEILAYTVSQSDNNGCDILFRLIGGT -KKVDAYIHSLGIKSIAIAATEEEMHKDWNAQFANWCKPRAMLRLLEIFYKGKALSKTSND -FLWKVMTETTSGPNKIKGLLPKSASVAHKTGLSDTKATNDAGIMTLPNGEHVAIVVFVSN -TPVDEKTRDGVIAQISKAAWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=UPI000B8849E2 --------IAAIERKHGGRLGVFVLDTGSGRTL-AHRAEERFLMCSSFKGVLAACVLARID -AGIDRLDSMIHYGRSDLLTSSPVTEAHVEVGMSVEALCGAILTQSDNAAANLLLARINGP -AALTKFARRLGDRTTRFDRTELDLNTA--SGLLDTTTPAAIVSTVRMIYLGRVLKPTTLT -VLERGMIANARGPRRLRGTLPRSWIVGDRTGTSDD-YCNDLAFARRPHAAPVVMAAYYEA -PGRTTEAREAVLREVGTRIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=A0A3N1CU24_9ACTN ---AARKALRALEREYDARLGVWALDTGTGDFV-DFNADERFAFASTFKPLVCGVLLQQAS ---DRRLAAVVRWKAADVVANSPVTARRTARGMTLAQLCEAAIRHSDNTAINLVLAEIGGP -KAFTDALHDLGDTATRSDRIEPAMSDVPPGETRDTTTPRAFATDLGAFLLGDALPDPRRA -LLADWLSRPLPLSAEIRGGLPDGWRVHGKTGTTANGGRNYIAVTHPPGRAPLLLAVLSTR -TDPSLPTDDTLLATA-------- ->[subseq from] class A beta-lactamase n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=UPI000F4C83B0 ---AARKALRALEREYDARLGVWALDTGTGDFV-DFNADERFAFASTFKPLVCGVLLQQAS ---DRRLAAVVRWKAADVVANSPVTARRTARGMTLAQLCEAAIRHSDNTAINLVLAEIGGP -KAFTDALHDLGDTATRSDRIEPAMSDVPPGETRDTTTPRAFATDLGAFLLGDALPDPRRA -LLADWLSRPLPLSAEIRGGLPDGWRVHGKTGTTANGGRNYIAVTHPPGRAPLLLAVLSTR -TDPSLPTDDTLLATA-------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9F1_SHIFL -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRLKLDSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMTDNTAAFLLLTTIGGP -MFRTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGEHGSRGIIAELGPDGKPSRIVVIYTTL -SQATMDVRNRQIALIGASL---- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Escherichia coli TaxID=562 RepID=A0A345N899_ECOLX --------------------------------------------------MAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLILV----- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium oranimense TaxID=421058 RepID=A0A1M5JYB2_9FLAO --sALEQKINSITKGKKATVGVSVLGFENNFKF-SKNGDKPLPTLSVFKFHIACAVLDLVD -QGKLSLDQKIFFKKEDILEWSPIREKYPEANLSLGEVLDYTVALSDNNGCDMLLRLIGGT -ETVQKFMDSKGVKGFQIKHNEDDMHKNWKTQYENYSTPNSAVLLLKKFYDGKLLSKKSTD -YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPDGKHYAIAVFVNN -STETDEVNCRMVSDISKAVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces salentinus TaxID=269421 RepID=UPI0012F8F3A7 ---RMSRELRALEAATSVRIGVHAVAQGGRRAF-RYRGDELFPMCSLFKPLAAAALVQARG -YDEAYWTTPIPFTDADLVVDSNVLDKLDPQEATPGELADAALRFSDNTAGNLILRELGGP -AAVTAFAASLGATDTRLDRWEPDLNQAIPGDERDTTTPDDIAHLYSALLLDEAAGLLAAS -QLRAWMLRNRTSDARMRAGLTPPYDLADKTGGGAYGVVNDAGVLWRPDAAPLTLAILTST -DRADAVRNNAVVAEATRIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Polyangium spumosum TaxID=889282 RepID=UPI00129A93C9 ---RLERDIAAAEARSGGRLGVAVVEPTSGERW-VHHAGQRFPLQSTFKAPLAAAVLARVD -AGALSLDTKIEVRRDDLSVWSPLAESFQGEAFSVLDLITESVTTSDNTAADVLMHQLGGP -ESVNVLLSKSAVVGIRVDRYERDLQLAYLRDPRDTTTPEAAADFLLKLDRGEMLGPTSTR -VLLDIMYATKTGAQRLRAGLPPGARLAHKTGTSANGATNDIGIATLPDGRKLVIVALLTD -SNAPQETREAALADVARAAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Curtobacterium sp. PhB115 TaxID=2485173 RepID=A0A3N1K9Y7_9MICO ---AVRRAISSLEREYDATIGVVAVDTATGATV-THNGDRRFGYASSIKVFAAAQFLRTVR ---GDARDEVVHWTADDVAAYSPVTEQHVADGLSYAQLAEAAVRMSDNTALNLVLTRIGGP -NGLDTALADLGDTTTEVVHGEPDLNTIEPGSTEDTTTPAAFTSALATVLDGTTLSTADTA -LLVSWMSGNATGDALIRAGAPDGWVVADKSGGAGP-IRNDVARVTRPDGDTIVLAVLTRR -DDPAQPYDDALVARSAAAVLRAf ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus boseongensis TaxID=1442587 RepID=A0A4R6T768_9BACT --qQISQKIERLSEKLAGRIGVAAQEIGSKEMI-TINGDEQFVMASTYKVAIAVALLDRVD -KGELKLSDLIDVEQETMVTGDGAIANHPGIKLSVANLIEPMITLSDNTATDACLKLAGGP -EAVTKMMRSIGITDLRVDRYTSEILRFEQEDPRDQSSPNAMLQLLLAIDSGKALSAESTQ -FLLSTMSRTRTGAARLKGLLPKGTPVAHKTGTIG-GVANDVGYVTLPDGRRFAIVVFTKS -STTSEADRDRAIAEVTRTLYDFy ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium epidermidis TaxID=1698 RepID=UPI000BF69A05 -hqRLEKQLKKLEDRYDARVGVSAFDTESGESV-DHRADERFGFASSLKAFAVAELLDRTT ---PKELEKNVTWTQADVDEWTPVTDKHVDDGLPLEDVAESALRVSDNLAMNIVLDELGGP -EALDDAMEKDGDTTTEVTDEEPELNDVEEGSTDNTTTPAAFTADLQGLLDPQRLSDDDRK -VLFDWMSGNETGDPLIRAGAPEDWVVRDKSGHSD-AIQNDIAMVTPPDRKPIVLSVMTET -DDPESEDGPAMVAAAAEAVLNEf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00066CC709 ---ATTEDLKKIEDKYDANVSVYALNTATDEEI-TFNEDKRFAYASTFKAVSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDITIKKLIEATMLYSDNTANNMIIEELGGY -KEVNKRLKSLDDKTTKPSRMEPELNNYDPKNNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVISETAKVV---- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=UPI000D166F47 ---DIDQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ -HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP -QGLTAFLRTIGDNSTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA -QLQFWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN -SKKTLPELNKVMVAISEKIFHQy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=L0HTV3_ECOLX ------------------------------SQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIAGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGY------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium angstadtii TaxID=558151 RepID=A0A0J7IE39_9FLAO --sALAQKIDAITKGKKATVGVSVLGFENNVKY-NKNGDRPYPTLSVFKFHIACAVLDLVD -QGKLSLDQKLFFKKEDMLEWSPIREKYPDANLSLGEVLDYTVALSDNNGCDLLLKLIGGT -QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVHVLKKFYDGKLLSKKSTD -YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPNGKHYAIAVFVSN -STETDAVNCKMVSDISKAVWDDf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=A0A494RLD3_9CAUL -------DLSALEARHGGRLGVAVAT--EGKRA-AWRGDERFVYCSTFKMYLAAATLLRVQ -SGLERLDRAIPITAADMVSHAPVTQPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -EPFRAFYRGLGDTITRVDRLEPEMNRL--DGDKDTITPDQSTRNIERLLVDTPLSPASKT -LLMRWMTETPTGQGRIRAGVPVGWTVAHKTGTGGYGPVNDIGLILPPTGAPIVLAVYFHA -TASTDAQREAVIAEATRQALK-- ->[subseq from] Beta-lactamase n=2 Tax=Curtobacterium sp. UNCCL20 TaxID=1502773 RepID=A0A1H0ZCL2_9MICO ----VAAALARLEQQYDATIGVVATDTRTGESV-TYNGDRRFGYASTMKVFAAAEFLRSVH ---GAARDEVAHWTAADTTAHSPVTEQHLADGLTYARLAEAAVRDSDNTALNLVLERIGGP -SALDAALADLGDDTTRVVHDEPALNTIEPGSTEDTTTPAAFTADLTKVLDGSTLGTADTA -LLVDWMSGNATGDTLVRAGAPAGWVVVDKSGGAG-GIRNDVARVTPPDGDPIVLSVLTAR -NDPGAAYDDALVAKTASVVLGAf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI000E6892DE ---ATTQDLKKVEDKYDANIGVYALNTATDEEI-TFNEDKRFAYASTFKALSSAMLLEKTP ---HNELNKKVHVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELDGY -KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLINDGRLSKENKT -FLIDLMINNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEIf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. legu1 TaxID=2602768 RepID=A0A5C7FCW2_9FLAO --qNLNKEIQKIVEGKKATVAVSVLDFGNNQSV-DLNGDQKLPMQSVFKFHIALAVLDYVD -EGKLKLEQKIFIKKSDLLEWSPIRNKYPDGNLPLSEIIRYTVAESDNNGCDLLLRLIGGT -ETVQNFMNSKGIKNFSITANEEEMHKDWKVQYRNFTTTNSMNELLKKFSEGKIVSEKSTA -FLIKTMLGTTTGTNKIAGQLPKNTPVAHKTGSSGTGAENDAAIITLPNSKKYALTVFVSD -SMESETENCKIISDISRKVWEY- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A556C4Z2_9MICO --eKVSSELESLEEDFEARIGVSAVDTGDGTSV-DYRSDERFGFASTLKVFAVAELLARTT ---SADLDEQVTWTQADVDEWTPVTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP -QGLDAALEDAGGPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDSDRLPEDDRE -VLLEWMSDNETGDPLIRAGAPEGWTVKDKSGHSD-GIQNDIAVVYPPNEDPIIITVLTQS -EDPDSEDGPALVAATAEAVFDSf ->[subseq from] Beta-lactamase n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A2N8QQB7_9BURK ---AAESPLADIERRRGGRLGVFAIDTGSGRTL-CHRADERFLMCSTFKGLLAAQILARID -SGAERLDRLVHYTQKDLIFTSPVTKTNVARGLSIDALYRAVLVESDNTAAILLMRSAGGP -AALTRFVRGLGDTVTRSDRYEPDSNRY--RGVLDTTTPKGIATTAQRLLLADVLSAGSRA -QLERGMTDCKPGLNRIRAVLPAGWQAADRPGTSVDSETNDYALVRPPGRAPLLVAVYYDA -PAIGMDARESVLREAGTAFV--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=A0A172Y9C4_9CAUL -------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFLYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMIAHAPVTAPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL -DALRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPAQSARNIERLILSEALESASKR -LLLEWMVASPTGQARLKAGVPSGWTVANKTGTGGGGPVNDIGVVYPIEGAPIIMAVYFHA -TPSTDAQREAVIADAARLALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas fluminis TaxID=2487274 RepID=UPI000F65746F --------LSALEARDGGRLGFVAQDLDSGRLL-AWRGDERFVYCSTFKMFLAAATFLRVQ -AGEERLDRMIPVTRADMVNHAPVTEPAIGDALSVEALMKGTVEVSDNPAANLLLKANGGI -DAMRAFYRGIGDADTTVDRYEPEMNRL--DGDKDTIKPLSSAANLKRLLIGDPLSAPHKE -KLLRWMIDTPTGQARIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPTGAPVIVAAYNHG -AGEAAPEREAVIAEATRLAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=UPI0013C53894 -------DLSALEARHGGRLGVAVAT--EGKRA-AWRGDERFVYCSTFKMYLAAATLLRVQ -SGLERLDRAIPITAADMVSHAPVTQPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -EPFRAFYRGLGDTITRVDRLEPEMNRL--DGDKDTITPDQSTRNIERLLVDTPLSPASKT -LLMRWMTETPTGQGRIRAGVPVGWTVAHKTGTGGYGPVNDIGLILPPTGAPIVLAVYFHA -TASTDAQREAVIAEATRQALK-- ->[subseq from] class A beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0011E8D936 ------------------------------------------------------------- ----------AHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas subvibrioides TaxID=74313 RepID=A0A258HFY0_9CAUL --------LSGLEQAHGGRFGLFAHDLGTGRQL-TARGDERFVYCSTFKMYLAAATLLRVQ -AGDEQLDRLIPVTRADMVNHAPVTEPAMGSSLTVERLIQAVVEVSDNPAANLLLKALGGI -APMQAFYRGIGDASTRVDRFEPEMNRL--DGDKDTITPAQSAANIHRLFIDPALSQDSKT -MLLGWMFSSPTGVDRIKAGVPADWRVAHKTGTGGYGPTNDIGILYPPIGEPIIVAAYYHA -AS-DRPGNEAVIAEATRLAL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rathayibacter TaxID=2609250 RepID=UPI000CE73834 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRSGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=G8EI98_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQ------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis terrae subsp. ummariensis TaxID=429001 RepID=A0A1Y6FTJ6_9SPHN ---SAANRIDALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK --SGVSLRTPLPFTRADLLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP -TGFTDHVQATGDLVTRLDRMEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRA -MLRDWLVKSETGLTRIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR -PALKGDAANAIIADVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=UPI001157695B ------QNIATIATESGGTVGVAIRNLHTGDTL-TLNDTARLPMQSAYKFPIAMAVLKQVD -EGKLRLDQTIPVTTADLFKYSPLQDSFPKGTQTVADLIRLMVAKSDNIACDVLLKTIGGT -KVANDYIHSLGVQNISIAATEQEMHSGWDVQFTNWCNVSAYTQLLDILYKGTALSKSSND -FLMQTMLGTTTGPKRLPGLLPAGTPVAHKTGTSGYSATNDAGIITLPNGQPLAVVVFVTR -STASEAVREGVIAKIAKAAYDHy ->[subseq from] class A beta-lactamase n=1 Tax=Cellulosimicrobium cellulans TaxID=1710 RepID=UPI00130EC038 ---AVEADLAALERSTGRRVGVYAHDTGTGDTV-AYRADERFGYASTLKALAAGELLAGQP ---ASVLDRPLTVTAEDVADHAPVTAGAAGTDLTIGALGAAAVTDSDNGALNVLLRHLGGP -AALEAALAARGDTVTLVDAAEPELNRFTPGDPARTSTPRALAEGLATYALGDALDPAVRQ -AYVGWLTASTTGLDAIRAGTPEGWTVGDKTGTAGYGSRNDIAVLWPPGRAPIVLAVLTDH -PDEAAEPDDAVLAAAATTVLAAy ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. VKM Ac-2805 TaxID=2609258 RepID=UPI0013202EE6 ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASGLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVATGDVLSAEDRV -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A2D7ZHW4_9CAUL -------------RAGEARLGVAVMNLENGDLW-AINGSDRFPMQSVFKAPLGAAVLAEVD -AGRLALDEILTVKDEDLSPYSPVAAAYPGRRYTVDELLTLAVGGSDNTAADVLMARIGGP -GAVTAWLRSHDIDHMRIDRYERQLQPRYLEDPRDTTTPRDALLFLAKLARGELLSEASTA -RLLRIMEDSPSGANRLAAGLPDQARLAHKTGTARTDATNDIGLITLADGRQYVVAVFLSG -STQPEAEREAIIADTARAVTQ-- ->[subseq from] Beta-lactamase n=2 Tax=Listeria kieliensis TaxID=1621700 RepID=A0A3D8TS10_9LIST --nSVNERLEVLENKYHAKLGVYAAN--GNEKV-KYNAQERFAYTSTYKAIISGLLLKNRT ---EEELQKKIFFSKEDLVDYSPITEKFVDKGMTLKAIIHAAVAYSDNTAGNLLLDEIGGT -KKFQEELRLIGDHTTISSRYETDLNSAVPGDLRDTTTPEAFGTDLQRLTSPKCLDPQALS -YFKQTLVDNTTGDKLIRAGVPEGYIVGDKTGAGSYGTRNDIAIIFKENGLPLVWAVFSKM -DREDAQYNDQLIADVAKVLS--- ->[subseq from] Beta-lactamase n=1 Tax=Serratia sp. S9 TaxID=2596922 RepID=A0A5C7DLF7_9GAMM ---TLQDQIKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] Class A beta-lactamase n=1 Tax=Corynebacterium mastitidis TaxID=161890 RepID=A0A2N0X915_9CORY --eKIQEEFHNVEAHYGATLGVYAVDTGSGRTV-EYRPDERFAYASTMKALAAGALIDGAG ---AEGLHREVAVTAEEIVPYSPVLENHVGENVTLMEAAKAAVVHSDNTAGNKIFEALGGP -EGLQRALRDRGDAATVSCRNEPGLNEAVADQECDTTTPRAVTENLRAYLVDGILNEDERD -LLQGWMEESATGMNLIRAGLPEGWKAGDKSGMGRFGARGDTAIIFPPNGAPIVMTVYARK -DDVDSHTEDAAIADSAAVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter sp. SA29-B TaxID=2695856 RepID=UPI00132AC027 ----LEAEIARLTAPIGGKVGVAAWQLDKGERI-MVNAGERFPMASTFKIAVAGAILASVD -AGRLQLDQLVAVQPNDIVPSDGIASLAIHPGLSVHNLLELMLTLSDNTATDVLTRLAGGP -QAVTAWVRKQGVEEQRIDRDTAGILRAFDKDVRDTSTPAAMGQLLTKIFNQQALSVSSTK -VLIDIMQRCHTGAGRLPGRMPAGTVIAHKTGTIG-GTVNDVGVMTLPDGSQIVIAVFIKE -SDKPMEQRERVIAEIARSVRDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Siphonobacter sp. BAB-5405 TaxID=1864825 RepID=A0A2N7B9Y4_9BACT --kSLQNQIEQLIQPKKATVGVSIYDFASKQIL-LIHGDKHLPMQSVYKFHVALAVLKEVD -KGRFKLEQKLHVKKSDLVPHSPMGEDHPNGELPLSEIIRYMVSESDGSACDYLFRLLGGP -TQVNAFIHQLGIKEVAIRETEETMQANWDVQYTNWTTPAAMLDLLKLFYQQKILSKRSHD -FLWKVMTETVTGENRLKKLLPTSTLVIHKTGTSGMGAVNDVGFIALPNGKHIAISVFVTN -TSEGIEKNEQIIADIAKLAYDHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A2W5KVQ9_SPHMC ----LSAKIAAIETRSGGRLGVAVTDADGTLRF-GHRADERFAMCSTFKLLLAGRVLSAAT --SGVPLRSPLDFTRTDLLPHSPGAEKLLDADYRIGFAARDAVVLSDNLAANLLLDRFGGP -AGFTAFVRGMGDEVTRLDRMEPDLNENAPGDPRDTTSPAAIARSGAQLVFGDRLHQSHRA -TLRDWLVESRTGLARIRGGLPQDWVAGDKTGTCGT-AYNDVAFVEQPGGGRHMIAIYLDR -PAVSGDAANAAIAGAARAIAE-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura madurae TaxID=1993 RepID=A0A1I5UV66_9ACTN -------RYAALEREHGARLGVFAVATGTGATV-AYRAGERFAFCSTFKTLAAAAVLHRHP ---LAHLEDRVTYTRADIDSISPITEDHVATGMTIRQLCDAAIRFSDGTAGNLLMRDIGGP -AGLTAYLRELGDGVSRMDDYEPELNRVRPGDPRDTTTPRAIAEDYRRLVLGTALPPDKRA -LIKDWLERSTTGAKRIRAGLPGGWKAAEKTGTGDYGRAN--------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Serratia nematodiphila TaxID=458197 RepID=UPI000B40BEC2 ---TLQDQVKQYEKE-GWKVGVSILS-SDDKTI-SINGNQRFPLDSTVKSIACANILAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=UPI0005D3CA03 ----IGQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ -HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP -QGLTAFLRTIGDNSTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA -QLQLWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN -SKKTLPELNKVMVAISEKIFHQy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2U9Q5I5_ACIBA ------------------------------------------------------------- -------------KPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAARI----- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xinjiangensis TaxID=762261 RepID=UPI000F7DE00C ------AELRALEESANGRLGAYILDLADGTAF-GWRADERFTHASSFKMSLAAMMLSKAD -AGQINLDEVLRWTKDDMLFVSPVTQANLNTGLSVRELARATLVTSDNTAANVLLRRFGGP -AELTAFWRSIGDLDSRLDRYEPELNVTPPGTELDTTTPAAMARTTARLVYGDVLTHGSRA -VLKNWMAQVKTGQGRIRSGFPLNWASGDKTGTGVKHVYVDLAYGEPPGRPPVVVTAYFEP -TRPMDPHAVAVLAAVGRIAT--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter bucti TaxID=2572203 RepID=UPI0011096C9C --qDLKAGITEIVGKANGTIGVGIMHLETRETT-IVNEKHKFPMQSVFKFPLAMAVLDQVD -KGKLSLDQKIHITKKDLLPHSPLRDKYPDGNITLAAILDATVSWSDNNGCDILFRLLGGP -KNVQAYIHNLGVKDIAIVATGEEMSRHWDVQFTNWCEPKAMLQLLNIFQKGKKLSKSSTD -FLRKSMVDSPTGPKRIKGLLPKTAVVAHKTGTSGTAANNDVGIITLPDGKHIALVVYVSN -STLDEKGRDLVIAQIAKAAYDHy ->[subseq from] Beta-lactamase n=3 Tax=Aeromonas TaxID=642 RepID=D5HSX5_9GAMM ----LKEQIETIVTGKKATVGVAVWGPDDLEPL-LVNPFEKFPMQSVFKMHLAMLVLHQVD -QGKLDLNKTVAVNRAAVLQWSPMMKDHQGDEVTVQQLLQYSVSHSDNVACDLLFELVGGP -AALHAYIQSLGIKETEVVANEAQMHADDQVQYKNWTSMKAAAQLLRKFEQKKQLSETSQA -LLWKWMVETTTGPQRLKGLLPAGTVVAHKTGTSGTAATNDIGVIMLPDGRPLLVAVFVKD -SAESARTNEAIIAQVAQAAYQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. WMMB499 TaxID=2650775 RepID=A0A5J6UCE8_9ACTN ---ALRKTLAELENSHDTRIGAVGIDLATGETV-GYRAGERFPFNSMFKVFACSAVLHEAR -TGRGLMDEVIRWTPDDMAANSPETTEYTDTGMTPAQLCRAGITKSDGFAGNMLLKQIGGP -SGLTAFFRSTGDRVSRLDRPEPYLTEWEPGRVRDTTTPAASARTFAELTTGTTLHPRDRA -RLVGWLDASLTGAERIRAGLPDDWTVGDKTGTGGHGSAGDIAIVRPPGSAPLILSVLTNR -KTDDTPNDNEVIARTATALAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044C6625 -------------KKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1H3 TaxID=2080567 RepID=UPI000CE83BF0 ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTAAGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIDPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSAR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0002B9AB3B ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGXLLTLASRQ -QLIDWME----------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=A0A2T3MQE4_9GAMM ----IGQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ -HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP -QGLTAFLRTIGDNSTRLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA -QLQFWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN -SKKTLPELNKVMVAISEKIFHQy ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. LPMIX5 TaxID=2305887 RepID=A0A399U9M3_9CAUL -------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTEPAVGRALTIEQLMKGAVEVSDNPAANILIREMGGL -EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPAQSARNIERLILSEALDSAFKR -LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGAPIAIAVYFHA -TKSTDAQREAVVADATRQALK-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium jeonii TaxID=266749 RepID=A0A0C1FRY6_9FLAO --qNLKKEIFDITKNKNATVAVSINSFENQFNL-NINGDKKLPMLSVFKFHIALAVLNKVD -EGKLSLNQNIFIKKSELLEWSPIREKYPEGNMPLSELIKYTVAQSDNNGCDILLRLIGGT -KTVQKFINSKGIKNFQIKANEEEMHQSYKAMYENFTTTNSANDLLKKFYNDKIVSKNSTN -FLMKIMIETTTGTNKIVAQLPKGTQVAHKTGSSGKNAENDIAIITLPNGKHYAISIFVSD -SMESAETNTKMIADISKIVFDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WJR8_9BACT --aELQKQIEQIAAAAKGRVGVRAVTLETGEAV-SLNPQEHYPMQSVYKLPIGMAVLEQVD -AGKIKLEERVRVEKSDYLKHSPIRDNNPDGTLSVRELLRLAVSESDGTASDVLLRLVGGA -EAVTKYLNRLKVTGIIVANSEKEIGQDWETQYRNWASPEGAVTLLRALHERRALSEQSTA -LLLKFMTESPTGPKRLKGLLPQGAVVAHKTGTSGNAATNDIGIMTLPNGRHVAIAVFVSD -SPAGIATSEAVIAKVARAVWDKw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. XJ-2 TaxID=2164099 RepID=UPI000D6A8703 ------QNIATIATEAGGTVGVAIRNLHTGDTL-TLNDTARLPMQSAYKFPIAMAVLKQVD -EGKLRLDQTIPVTTADLFKYSPLQDSFPKGTQTVADLIRLMVAQSDNIACDVLLKTIGGT -KVANDFIHSLGVQNISIAATEEEMHSGWDVQFTNWCNVSAYTQLLDILQKGTALSKSSND -FLMQTMLGTTTGPKRLPGLLPPGTPVAHKTGTSGYSATNDAGIITLPNGQPLAVVVFVTR -STASEAVREGVIAKIAKAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2A3ZKX6_9MICO --qKVSGELESLEEDFKARIGVSAVDTGNGTNF-DYRSDERFGFASTLKVFAVAELLARTT ---SADLDEQVTWTQADVDEWTPLTEKHVDTGLPLRDVAESALRVSDNAAMNIVLDEIGGP -RELDAALEDAGDPTTEVIDEEPELNDVDPDSSDNTTTPKAYTADLQGLLDPDRLPEDDRE -VLLEWMSDNETGDPLIRAGAPKGWTVKDKSGHSD-GIQNDIAVVYPPSEDPIIITVLTQS -EDPDSEDGPALVAAAAEAVFDSf ->[subseq from] Class A beta-lactamase n=1 Tax=Actinomadura sp. WAC 06369 TaxID=2203193 RepID=A0A429G226_9ACTN --tALDETLAEIEKSRGVRIGAAGIDLATGKTV-GYRAGERFPFNSMFKVFACSAVLHKAR -TDPGLMDKVVRWTPGDMTGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNKLLDQIGGP -SGLTRFFRTNGDRVSRLDRPEPHLTEWEPGQVRDTTTPAAAARTFTGLTTGNALHPSDRA -RLVGWLKASLTGADRIKAGLPSDWTVGDKTGTGGHGTAGDIALVWSPGTEPMVLAVLTNR -TTDDTPHDDKAIAETATALA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JKT8_SPHSX --------VADYETASGGHVGLYARNLTTGRAI-AWRADERFVMCSTFKASLAACVLNRVD -RGRARLADRIALSPADLQDHAPVARQNLARGMSLGEMCQAAVEQSDNSCANILLQRIGGP -AALTAYWRGLGDDVSRLDDIEPFLNRTPPGGLRNTTTPRAMAATIGRMTRGPVLSPSSRA -LLMLWLRQCRTGAARLRAGLPRGWAIGNKTGNNGKDAAGDIGLLWRDPDRP--------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. TaxID=239 RepID=A0A5N7ZE08_FLASP --nRLKAQFQEIVKDKKATVGIAVYNFTTGDTL-TFNNNPEYPTLSVYKFHVALAVLHLVD -KGTLKLDQEIFVKKSELLEHSPLRENYPYGNIKLSELLSYMVSLSDNNACDILFRLAGGT -KKVDRYIKNLKIKDTRIAATEEEMHQKWENQYLNTTSPWAAVQLLQKFYQMKILSPTSYD -YLLNVMLSTKTGPDKIKGLLPKDILVAHKTGSSFKAAENDIGIVFLPGGQTYAIAVFVKD -SMEDDTTNNAIIARVSKAVFDHy ->[subseq from] class A beta-lactamase n=1 Tax=Indioceanicola profundi TaxID=2220096 RepID=UPI000E6AD44B ----LEKALSDLATAHPGRVGIGVRDLATGATT-LVGGGRRFPMQSVFKFPIGIAVLDAAD -RGALTLDQTVKLTPADMSVWSPLRDRLAGQPDTVRELLELMVAQSDNTACDVLLGMIGGP -EAVTALLRAKGIDGVRVDRAERELQTAYLDDPRDTSTPEGMLDLLAAFHDGRMLSEAGTA -ELRRIMLSTTTGTKRLKAGVPPGWRVAHKTGSGWTVANNDVGLLIAPNGRTLAIAVFIAG -STAPMEEQEALIAAAARAAT--- ->[subseq from] Beta-lactamase n=1 Tax=Francisella opportunistica TaxID=2016517 RepID=A0A345JRR1_9GAMM ---QVNNDIQNIEKKYGGKIGVYTINRNDGSNF-AVNASFYFPICSTYKFLVVGALLKQSM -TDNKLLNQQVKISKNQIVGYSPITKKHINQTMTVRELCKASMQ-GDNTATNILIEKLGGL -KNLNKFILSLQDHATKIANLEPKVNHVSLTTNENKTTPKVMAKDINKLAFNDLLDKKHRL -MFKKWLIASSTGNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKILREVTKILLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI0009C33872 ---TLQEQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium defluvii TaxID=160396 RepID=A0A495SNP3_9FLAO ----LEKRINTILKDKKATVGVSVLGIETGFQY-NKNGEKKLPMQSVFKFHIACAVLDFVD -QGKLSLDQKILLKKSDLLEWSPMRDKYPNGNVTLNEIIDYTVALSDNNGCDILLRLIGGP -KTVQKFMDSKGVTGFQIKFNEEEMHRDWNVQYENYSTTRSIVQVLKKFYDGKLLSKKSTD -YLMKVMLGTKTGANKIVEQLPKTTPVAHKTGASGTGAENDMGIITLPNGKHFAIAVFVSN -STETDAVNCKIVSDVTKVVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI00114EF3C2 ---TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYINKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Serratia TaxID=613 RepID=UPI0007455437 ---TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWEIADRSGASDYGVRGITSMVWSNNHDPIFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter cummioxidans TaxID=1803913 RepID=UPI000E30F3D6 ----LEAEIARLSAPIGGKVGVAAWQLDKGERI-LVNAGERFPMASTFKIAVAGAILANVD -AGKLQLEQLVAVQPTDIVPSDGVASLAIHPGLSVQNLLELMLTLSDNTATDVLTRLAGGP -QAATAWVRKQGIEDQRIDRDTATLLRAFDNDVRDTSTPTAMAQLLTKIFNQQALSVSSTK -VLIDIMQRCRTGTGRLPGRMPAGTVIAHKTGTVG-GTVNDVGVMTLPDGSQIVIAVFIKA -SDQPMEERERVIAEIARSVRDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Mycobacterium sp. GA-1841 TaxID=1834154 RepID=A0A1R0V2S8_9MYCO ----------------------------------------------TFKAYAVARVLQLVE -RGQLSLDHRVFVDPQAIVPNSPVTETHAGAEMTVAELCQAALQRSDNTAANLLLKAIGGP -AAVTEFARSVGDERTRLDRWEVELNSAEPGDARDTSTPAALAVGYRAILTGDALSPAQRR -QLDDWMRANQT--SSMRAGLPEGWTTADKTGSGDYGSTNDAGIAYGPGGQRILLVMLTRS -QADDAENQRPVIGELTALV---- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E6 TaxID=2080554 RepID=UPI000CE87B57 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLAAVAIGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Oceanicola sp. HL-35 TaxID=1305735 RepID=UPI0009DCB0CD --------------------------------------------------------LSRVD -AGKEDLSRVVKYTPDDLVTYSPLTETRVEDGMNVAGLCEATVTLSDNSAGNLLLTTLGGP -EGLNTFLRSIGDETTRLDRWETELNEGALGDPRDTTTPTAMLASLESLLFGEVLSETSRE -QLADWMVADQVADELIRASLPEGWRIGDKTGAGGNGSRSVVAVIWPPEGGPVLAAVYMTD -NTAEFRARNEAVAEIGAIMIE-- ->[subseq from] Beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=A0A1S1IST8_SERMA ---TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas alba TaxID=74314 RepID=UPI001439AA73 --------LSVLERENGGRLGFVAHDIGSGRRL-AWRGDERFVYCSTFKMYLAAATFLRVQ -AGEERLDRMIPVTAADMVNNAPVTEPAIGGTLSVEALMKGTVEVSDNPAANLLLKALGGL -DVMQAFYRSLGDDSTTANRFEPTMNRL--DGDKDTITPLHSAANLKRLLVDTPLSAGHKA -MLLRWMTDTPTGQARIKAGLPTGWTVAHKTGTGGYGPTNDIGVLYPPTGAPVIVAAYYHA -STEPVARNEAVIAAATRQAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas soli TaxID=266127 RepID=UPI000A052EFA ----AIAELRALEQSANGRLGAYILDTATGLGF-GWRENERFAHASSFKMSLAAMILAGAD -AGTIDPDEVLRWTSKDMLWVSPVTKANLDKGLSIRELAKATLITSDNTAANVLMRRLGGP -EKVTAFWRSIGDNVSRLDRYEPELNETPPGTDLDTTTPAAMAASVARLVHGDALALQSRA -LLRAWMAEVKTGQARIRAGFPAEWHSGDKTGSGIKHVYVDLAFGGPLGRAPLIVTAYFEP -KRPMDPQAEAALAAVGRLAA--- ->[subseq from] Class A beta-lactamase n=2 Tax=Photobacterium TaxID=657 RepID=A0A2T3KNR6_9GAMM ---DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSNHFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP -QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMNTIKKLLTGNVLDSENKA -QLQLWMTNNMVSDDLARAVLPRGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN -SKKTLPELNRVVASISAKIFNKy ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacterium sp. S22 TaxID=2483794 RepID=A0A4Z0JXR3_9MICO -hrQLDTQLTNLEDRYDARIGVSAIDTGTGEAV-DHRGDERFGFASSLKVFAVAELLDRTT ---PKQLKKHVTWSQADVDEWTPVTSKHVDDGLPLAEVAESALRVSDNAAMNIVLDELGGP -DGLDEALHKGGDTTTEVTDEEPELNNVEAGSTDNTTTPAAFTADLHGLLDPQRLSDDDRD -VLLDWMSDNATGDPLIRAGAPDGWTVQDKSGHSD-AIQNDIAVATPPDRDPIVVSVLIET -EDPESADGPAVVAAVAEVVLDEf ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium kishitanii TaxID=318456 RepID=UPI000D16BE8C ---DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSNHFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP -QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMHTIKKLLTGNVLDSENKA -QLQLWMTNNMVSDDLARAVLPRGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN -SKKTLPELNRVVASISAKIFNKy ->[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium RIFCSPHIGHO2_01_FULL_70_19 TaxID=1797585 RepID=A0A1F8I429_9PROT --------LSSLEARNGGRLGFVALDTAGGRSV-GWRAQERFVYCSTFKMYLAAATLERVQ -RGEESLAREVSVVAADMVSHAPVTEPAIGSTLSIEALCKAVVEVSDNPAANILIREYGGL -AAWRDWYRSIGDESTTVDRLEPEMNRE--DGDKDTILPAQSVANMQRLFVNDPLADDSRD -RLLRWMIDSPTGAGRIKAGVPAGWTVAHKTGTGGYGPTNDIGLAVPPSGDPVVIAAYYHA -TPSSASANDAVIAEAVRLAL--- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. BAL39 TaxID=391596 RepID=A6EA88_9SPHI ----LKQKIKQQLSGKKATVGISIQHLETGQTL-TINNDKHYPMQSVYKFHIAMAVLNQVD -KGKLQLQQNIYIKKSDLLPWSPIREKYPEGELPLSDLIRYTVAQSDNNGCDILLRLLGGP -KLVNNYIHKLGIEDVSIQATEEQMHQSYPVQFSNWSTPKAATDLLLLFYQQNTLSKQSFN -FLWETMLSTTTGKKQLRGQLPLNTPVAHKTGNSGTAALNDIGIITLPDGTHILISVFVSN -SKENSETNESIISDIAKTAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NF23_9BACT ----LNHTIAQFAQRSQGKTGVFAQVLETGDTA-GFYATDRFPMQSVYKVPIAMAILAQVD -KGKWQLSDSILVLPSDLLKHSPITDEHPQGNITLADLLQLAVGESDGTASDVLLRILGGP -QKVKKYLHHIGVKHVAVANTEKEIQGEWEVQYSNHATPEAIGKLLRTLYTKDALSLPSRD -ILLKWMTESTPGAARIKGLLPPGTPVAHKTGTSATAATNDAGIITMPNGHHLVVVVLVSN -SPADTPTRENVIASITKTLWDTw ->[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LSP8_9BACT --kKLRNEIEQITLAAKGRVGVAAVVLETGETV-SLSPHDHFPMQSVYKLPISMAVLKQVE -AGKIKLDQKVSVTKKDFVRNSPIRDKYPNGTITVNELLRYAISESDGTASDVLIKLAGGP -GAIQTYLSELKITDLTVLNTEKEIGQDWETQYRNWSSPEAAVALLRALHERRGLSGSSQT -LLLKFMIESTPGPKRLKGLLPTGTIIAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVAD -SAADEASREGVIAKIARAVWDTw ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis terrae TaxID=33052 RepID=UPI000787EF97 ---SVANRIDALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK --NGVSLRTPLAFTRADLLPHSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP -TAFTDHVQATGDLVTRLDRVEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRT -MLRDWLVKSETGLARIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR -PALKGDAANAIIADVARAVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3A6RJC2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDW------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI001021B0D8 ---TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGSQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNLVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDSSKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] class A beta-lactamase n=1 Tax=Shewanella aestuarii TaxID=1028752 RepID=UPI001425E060 ----IAQKLEALSKGLVGSIGIAAQEMSTGECI-TVNGDESFVMASTYKVAIAVTVLRQVD -EGKLKLTDLVDCPAEKMVAPNPLATYHPGVKLSVANLIEPMITDSDNSATDFLLELVGGP -EVVTQMLRSLGITDFRVDRYVSEILRDYEKDPRDQTTPNAMLQLLLAIDNGTALSEESRE -FLLGVMSRTTTGKARLQGLLPKGTPVADKTGTIG-GVANDVGYVTLPDGRRFAIAVFTKS -SATSEAQRECAIAEVTRSLYDFy ->[subseq from] Beta-lactamase n=1 Tax=Dyadobacter sediminis TaxID=1493691 RepID=A0A5R9KEK7_9BACT --dELHASIDSISKRVQGTVGVGIMELKSGETF-FLNKAHKFPMQSVFKFPLGMAVLHQVD -KGKLSLDQKIHVTKDDLNPWSPLQKKFPEGNISLRDLLIYTVSLSDNNTCDILFKLVGGP -RNVNKYIHNLGVKDINIVATEAEMAKSWDVQFTNWCQPPAMIQLLHILHQGKNLSESSTE -FLLKIMTETPTGLNRIKGLLPENTKVAHKTGSSGTNAFNDAGIVTMPNGKYIAIVAFVSN -TAADEKTRDLVIAQISRAAWDYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3D3MJU5_9FLAO --kALDNKINAVIKDKKATVGVSVLGFENNFTY-DKNGDKKLPMLSVFKFHLACTVLNLAD -KGKLSTDQKILIKKEDLLEWSPLREKYPNGNLSLGEIIDYTVSKSDNNTCDLLLRLIGGP -QAVQHFMNSKGVKNLQIKYNENDMHKDWKTQYGNYSTTHSAVDLLKKFYDGKIISKKSTD -FLMQIMLGTTTGTNKIVAQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN -STESDEVNTKMVADISKIVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Tanticharoenia sakaeratensis NBRC 103193 TaxID=1231623 RepID=A0A0D6MMF7_9PROT ------ASLAALERRIGGRVGVCALDTGTGARI-VYRETERFVMCSTFKWLLAAAVLQRAA -SGGPGLDSSVPIRADAIVSHSDATKPFVGRSMTLRLLCAAMMATSDNGAANTLMRAIGGP -AALTRAVRTWGDPLTRQDTYELGPD-ARPGDLRNTTTPAQMLADMQHVWLGDALDPASRA -QLIAWLRSCVVGQHRLRTGVPGQWVEGDRTGTGDPGSINDLAIFWPSKRAPVLVASFLSG -SQHSAVQLETAQGEIGRIVADTf ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00069EA316 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKKQEPIILVIFTNK -DNKSDKPNDKLI----------- ->[subseq from] class A beta-lactamase n=1 Tax=Listeria thailandensis TaxID=2268407 RepID=UPI000F091C5C ---SVNERLEVLENKYHAKLGVYAAN--GNEKV-KYNAQERFAYTSTYKAIISGLLLKNRT ---EEELQKKIFFSKEDLVDYSPITEKFVDKGMTLKAIIHAAVAYSDNTAGNLLFDEIGGT -KKFQEELRLIGDHTTISSRYETDLNSAVPGDLRDTTTPEAFGTDLQRLTSPKCLDPQALS -YFKQTLVDNTTGDKLIRAGVPEGYIVGDKTGAGSYGTRNDIAIIFKENSLPLVWAVFSKM -DREDAQYNDQLIADVAKVLS--- ->[subseq from] Class A beta-lactamase n=1 Tax=Francisella halioticida TaxID=549298 RepID=A0A2Z2LDL7_9GAMM ----ISNNIHKIESHYGGKVGVYTINRNNGQNF-SHNETFYFPICSIYKFLVVGAILKESM -ADSNLLDEKIRISGNQIVGYSPITKKHIGKEITVRQLCKASI-LSDNTATNLLIDKLGGL -KKLSTFILSLKDHATKITALEPKINDISLNNNLNKTTPKIIVRDLNKIAFKNILDKKHRT -LFKKWLEENNTGSNRIAAELPKDWKIGDKTGTCDYGSTNDVAIIWPNNDKAIIMAIFYTQ -PNKNAKPNNKVIREVAKILFDNf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. SNU WT5 TaxID=2594269 RepID=A0A516NZ93_9FLAO ---TLKKEIKQIIKGKNATVAVSVLDFENNKSI-DINGNKKLPMLSVFKFHIALAVLNQVD -EGKLSLDQNIFIKKSELLLWSPIREKYPEGNMPLNELIKYTVAQSDNNGCDILLKLIGGT -GTVQSFINSNGIKDFQIKADEEKMHQGYEFMYWNWTTTNASNTLLKKLFDGKVVSKKSTD -FLMKTLIETTTGVTKIVAQLPKGTPVAHKTGSSGKDAENDIGIITLPNGKHYAISVLVSD -SMESEETNTKTIADISKIVFDYf ->[subseq from] Class A beta-lactamase n=4 Tax=Hyphomonadaceae TaxID=69657 RepID=A0A354C945_9RHOB -----HTAIAYMESQNGGRFGVSAVNLATGQTI-THRGDERFAMCSSFKWLLAALVLQRVQ -AGEEDLSRMIEFTEADMVMHAPITEPALGEGLSVEALCRGTVQTSDNPAANLLLRTLGGP -EGFTQILRDNGEMTTRLDRWEPMLNENAPGDPQDTSTPNAMVSLMGYYLFGGGLNAEYQT -LLKDWMIGATTGLARLRDGMDAPWIGGDKTGTSSNNQSNDVAFAYRPDADPILITSYLNV -ENPVGAETDELHATIGRQIM--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseoflavus Tu4000 TaxID=467200 RepID=D9XL75_9ACTN ------------------------------------------------------------- -----RLDRRVTYTRADLVPHSPVAEKHLATGMTVRQLCDAAIRFSDNAAANLLLRDLGGP -RAVTAHLRRLGDRVSRLDQSEPELNGNPPGDPRDTTTPRAVAADYRALVLGDALPGAKRD -LLADWLVRNTTGGRRIRAGVPRDWRVGDKTGTGEWGRVNDVAVLWPPSGAPLVMAVLTDR -PGRADTTDEALVAEAARRVL--- ->[subseq from] Class A beta-lactamase TEM family n=1 Tax=Citrobacter braakii TaxID=57706 RepID=A0A3S8XA06_CITBR ------------------------------------------------------------- --------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium kishitanii TaxID=318456 RepID=UPI000D15D39D ---DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSNHFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP -QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMNTIKKLLTGNVLDSENKA -QLQLWMTNNMVSDDLARAVLPRGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN -SKKTLPELNRVVASISAKIFNKy ->[subseq from] class A beta-lactamase n=1 Tax=Microvirga flocculans TaxID=217168 RepID=UPI00047FA4C3 --dALRAKIEALDKKSSGRLGVGLVDLTDGDSW-SWRGDESFPMQSVYKLPIALAALKAVD -EGRRNLDERISLGREDLSIWSPIAREFKGEPYTVRQLLEHALQQSDNTASDVLLRLVGGP -GSVTALLRRHGIDGMRVDRPEREMQPAYLADGRDTATPKAAAHLLAKLARGELLSKPTTR -IFLDILAGTRTGGSRIKAGVPEGSTVAHKTGTAMDVAVNDAGLVTLPERRQLVVAVFVAG -SDSSPAERERLIADVTRAAIE-- ->[subseq from] Uncharacterized protein n=1 Tax=Williamsia sp. Leaf354 TaxID=1736349 RepID=A0A0Q5QA65_9NOCA ----IDAQIVASAKRAETTIGVWARDLRTGRVIaAVNAGERFPVLSMSKVYLAAAVLDAAR -HGRLLLTRPVPVRASDIVANSPETGKHVGGTMTYPEIAVAALQLSDNTAANLMFAAIGGP -RALTAFARSTGDPATLMVRQETALNTAFPGDVRDTTVPQAWAAGLRAVMVGTRLDPRDRT -TLVGWMRGTRTSDKRFRADLPAGWTTADKTGTGDYGSADDAGLLIGPGGRRILLVVQTRN -ARPDATAADTVIARVASLVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Eudoraea adriatica TaxID=446681 RepID=UPI00036495FD --kEVSQKIEKLTEGLVGRIGVAAQEIGGDEVI-AVNGDETFAMASTYKVAIATTVLDRVD -KGELSLDQMVDVPQDMYVATVAIAERFPYSGFSLANLIYAMITESDNTATDVCLRLAGGP -AAVTENLRRLGIKDFRVDRSVREILMDFEADPRDHTTPNAYLKLLLAIEGGKAMSPKSRE -FLLGVMSRTRTGAGRLRGMLPKGTPVAHKTGTLG-GVANDVGYITLPDGRRFAIAVFTNS -SKTPDSDRERAIAEVARALYDFy ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=UPI00065C1A99 ---ATTQDLKKVEDKYDANIGVYALNTATDKEI-TFNEDKRFAYASTFKAISSAMLLEKTP ---HDELNKKVYVSKEDIVPYSPVLEKFINKDISIKKLIEATMLYSDNTANNMIIEELDGY -KEVNKRLKSLDDKTTKPSRMEPELNNYNPKSNRDTSTPQAFGKTLNKLIKDGRLSKENKT -FLIDLMVHNKSGDTLIKKGAPKNFKVADKSGQATYASRNDVAFVYPKGEKPIVLVIFTNK -EGKTDKPNDKVVSETAKVVLEKf ->[subseq from] Beta-lactamase (Fragment) n=6 Tax=Escherichia TaxID=561 RepID=A0A345N8A2_ECOLX ----------------------------------------------------VAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLILV----- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter nutrimenti TaxID=1241337 RepID=A0A318U9U3_9SPHI ----LHKKLNAIAAAHQAHIGFSLLDLQSGDTV-SLNGQKHFPMQSVYKFHLALAVLNKVD -QGKLKLEQKIHLRKQDLLPWSPLRDKYPSGEIPLSELLSFTVSQSDNNGCDILFRLIGGP -IAVQRYIHGLGIKDVAIVATEEQMHQNDQVQFRNWSTPVSAARLLKLFYSKNILSASSKD -FLWKIMTETTTGPNKIKGMLPKGTPVAHKTGSSGTAATNDIGIVTLPNGGRFALVVFVSM -TKENEQGSDKIIAELSKAGWDY- ->[subseq from] Beta-lactamase n=1 Tax=Zymomonas mobilis TaxID=542 RepID=A0A542VZ02_ZYMMB -----EEIAREYERATGGHAGIYAQNIATGQSI-AWRANERFLMCSTFKASLVAFTLLRCD -QRQESLNHSVDYKAADIGDYAPFAKSNLGRGMSVAELCQGAIEQSDNFCANKLLACSGGA -LALTEFWRQIGDYESRLDAIEPFLNETRYGGIENTTTPASMARNLQKVVLGGVLSETSKQ -QLATWLKGCRTGQNRIRAGLPENWVIGDKTGTNGANAAGDIAVIWPRPDKAITLSIYVWG -GSPTADQMTALFSKAARLVAK-- ->[subseq from] Uncharacterized protein n=1 Tax=Flavobacterium sp. 40-81 TaxID=1896169 RepID=A0A1Q3S2N9_9FLAO ---NLRAQINEIIKDKKATVGVGIYNLTNNDTL-TINNTHHFPTMSVYKFHLALAILHQVD -KGKLRLDQEIFVKKSDLLEHSPLRENYPYGNIKLSELISYTVSLSDNNACDILFRLAGGT -KKVDRYIKSLKIPNTSIQATEAEMHEKWENQYLNTTTPFAAVLLLKKFYQLQVLSPTSYD -YLLNVLQGTKTGPDKIKGLLPQNVVVAHKTGSSFKAAENDIGIVYLPGGQAFAIAVFVSD -SMESDTTNNKIIAAISKAAFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. H66 TaxID=2529859 RepID=UPI0010A9B0B7 ---RMTAALAELEREASVTIGVVAVAHGSTNPF-RYRAADRFPMCSLFKPLAAAALVQARG -YDEVYWNTPIPYTNADVVVDSLVLESKRPQRATPEELADAALRWSDNTAGNLLLRELGGP -AAITAFAASLGATDTRLDRWEPELNEAVPGDLRDTTTPDDIALLYSALLLDDAAGMLTSA -RLREWMLRNQTSNARMRAGLEPPYELADKTGGGAYGVVNDAGVLWRPGETPLTLVIMTRT -DRADAVRNNAVVAEATRIVV--- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium sp. SKA34 TaxID=121723 RepID=Q2BZ61_9GAMM ---ELNITLRQMEKQIDGNIGVAVFDSQTNTSW-NFNGNKRFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPVTQNFVGGQMSLNSVCGAAMLMSDNYAANLALGQVGGP -HGVTKFLRMIGDKTTRLDHFEPKLNYVEKGAENDTTTPIAMMNTIKKLLTGKVLDSESKV -QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKHHQPLFIGIFISN -SKETLPELNQVVASISAKIFNKy ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter oceanensis TaxID=1463597 RepID=UPI00136F9993 --qDLASRMAEIEAASGGRLGVALHSPDAGTVF-LHRGDERFAMCSSFKLALAAMALERPG -----LRDARLGFGPDEVLGYAPYAKQRAALGMSGLEAARHSVTISDNTAANLLLAELGGP -DGFTAWLRGFGDDKTRLDRNEPALNENAPGDPRDTTTPQAHAKLVADLLWGDRLAAADRS -LLREWLVETSTGMNRLRAGIPDGWQAGDKTGTCGNGQVNDIAVFETPDGARYVLAVYLDR -PSGTTAEAEAAIAQAARAIVA-- ->[subseq from] class A beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0013A59627 ------------------------------------------PMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANFLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTG--------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=E4WMC5_9BACT --rELQKQIEQIASAARGRVGVHAVVLETGESV-SLDEQGRFPMQSVYKFPIGMAVLAQVD -AGKLKLDERVRVEKSEYVRHSPLRDKNPNEAVSVRELLRLAVSESDGTASDVLFRLAGGS -EAITRYLSDLKVTEIIVADTEKEIGQDWDTQYRNWASPKGAVMLLRAFHEGRGLSAESRA -LLLKLMTDTPTGPKRLKGLLPKGTVVAHKTGTSGSAATNDIGIVTLPNGRHLAIAVFVSD -SPADLTTREGVIAKVAKAAWDQw ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X339_9BACT --aKLKSEIETISKQAKGIVGVGIMDLKTQETL-LINQDHKFPMQSTFKFPLAIAVLDLVD -KGKYKLDQTIHVTKAQIDTHSPMRDKRPNQDITLAELLSYSVSESDNNACDILFELAGGT -KKVNDYIHSLGVKDIAIVATEREMKAGWDVQYTNYSRPSAYLQLLQIAYERKKLSKASHD -FLWKTLVEGPTGLKRIKGQLPKGTEVAHKTGTSGTSATNDVGIVKLPNGKDIAVVVFVSD -AAADIDTRELVIARIAKAVWDYy ->[subseq from] TEM-1 beta lactamase n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A3G1IEN2_KLEPN ------------------------------------------------------------- --------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. 1.3611 TaxID=2559600 RepID=UPI00112E5B9D --qDLKKTIETIVGKHTAKIGFSVIDLQNGDTI-GFNGNVRYPMQSVYKFHLALAVLKQVD -EGKLKLDQQIFVTTKDLLPWSPLRDKYPQGNIPLAEILSYTVSQSDNNGCDILFRLVGGP -SEVKRFIHGLGIKDVNILATEEEMHLDEMVQFKNWSTPCAVVQLLKLFYDSKILSTSSND -FLRDIMEKTVSGPNKIKGLLPKGTTVAHKTGSSGTTASNDIGIVTLPNGKHFAIAVFVSM -TNEEEKETDQIIAECSKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudarthrobacter chlorophenolicus TaxID=85085 RepID=UPI0005F281B7 ---RLDTAISGLESAHGLTIGVAAGRLGQRPAY-AYRGGDIFPMCSLFKTLAVARLLRDHA -YDDGFWQHRISFRKNQIVRDSVICAADKDRNMSVEELADAALRFSDNTAGNLLLELIGGP -PEIGTYARSLGALSTRLDRWEPELNEALPGDVRDTSTPSDIHTLYEALLLGDALGTLGQA -RLRGWMLRNATSGERLRAAVPPGAELADKTGAGSYGVVNDAGVVWPEDGPPLTLAVMTRT -SRPDAVNNNAVVARVGQLVF--- ->[subseq from] Class A beta-lactamase n=1 Tax=Photobacterium kishitanii TaxID=318456 RepID=A0A2T3R2T3_9GAMM ---DLEQYLRHTEQQIQGQIGVAIIDTQQHSQW-NFNGSSHFPMMSAFKTLACANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPITQNFVGGQMSLQSVCGAAMFMSDNYAANLVLEQIGGP -QGLTEFLRTIGDKKTRLDHFEPKLNYVEKGALNDTTTPIAMMDTIKKLLTGNVLDSENKA -QLQLWMTNNMVSDGLARAVLPAGWKIADRSGGGVNGSRTLTAMVWNEHQQPLFIGIFIAN -SKKTLPELNRVVASISAKIFNKy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium phocaeense TaxID=1816690 RepID=UPI0009BB558C --sSLEQKISSITSGKKATVGVSVLGFENNFKY-SKNGDKELPMLSVFKFHIACAVLDLVD -KGKLSLDQKLFFKKEDMLEWSPIRDKYPDANLSLGEVLDYTVALSDNNGCDLLLKLIGGT -QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNVSTPNSAVLVLKKFYDGKLLSKKSTD -YLMQMMLGTKTGTNKIVEQLPKGTPTAHKTGASGKGAENDIGIITLPNGKHYAIAVFVNN -STESDAVNCRMVSDISKAVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter agariperforans TaxID=268404 RepID=UPI00101C7C58 ----LEAEIARVSAPIGGKVGVAAWQLDKGGRV-MVNANERFPMASTFKIAVAGAILANVD -AGKLKLDQLVAVQPNDIVPSDGIASLAIHPGLSVHNLLELMLTLSDNTATDVLTRLAGGP -QAVTAWVRRQGVEEQRIDRDTAGLLRAFDKDVRDTSTPAAMGQLLTRIFNQQALSVSSTK -VLIDIMQRCHTGAGRLPGRMPAGTVIAHKTGTIG-GTVNDVGVMTLPDGGQVVIAVFIKE -SDKPMEARERVIAEIARSVRDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E3 TaxID=2080551 RepID=UPI000CE768A8 ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Williamsia herbipolensis TaxID=1603258 RepID=UPI0005F818B2 ----IDAQIVASAKQAETTIGVWARDLRTGRVIaAVNAGERFPVLSMSKVYLAAAVLDAAR -HGRLSLTRPVPVRASDIVANSPETGKHVGGTMTYPEIAVAALQLSDNTAANLMFAAIGGP -RALTAFARSTGEPATLMVRQETALNTAFPGDVRDTTVPQAWAAGLRAIMVGTRLDPRDRT -TLVGWMRGTRTSDKRFRADLPAGWTTADKTGTGDYGSADDAGLLIGPGGRRILLVVQTRN -ARPDATAADAVIARVASLVAR-- ->[subseq from] class A beta-lactamase n=1 Tax=Streptomyces glaucescens TaxID=1907 RepID=UPI000A35F787 ----LTKKLQALERSYEGRIGAVGIDLETSRTV-GYRADERFPFNSSFKVFACAAVLVKAR -TDPGLMDQVVRWTPADMGGNSPESTEYTDTGMTPAQLCRAGITKSDGFAGNMLLEQIGGP -RGLTAFFRAIGDRTSRLDRPEPLLTEWEPGEVRDTTTPAAAARTFTELTTGSTLRAGDRA -RLVGWLKASLTGANRIRAGLPKDWTAGDKTGTGGHGTANDLAIVWSPGSAPLILSVFTNR -THDNTAHDDKVISSTATALA--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. (strain NBRC 103272 / SYK-6) TaxID=627192 RepID=G2IJJ9_SPHSK --eAARQALAALETRSGGRLGVAMLDSRDLALV-GHRQDERFTMCSTFKLSLAAAMLVRMD -AGAFGEQERLLITRDDAVGHAPAVRAALEDGMTVLDLCAAAQIESDNGAANILLRKLGGP -EALTRFWRALGDDVSRLDRYEPALNTSHGEDIRDTTSPAAMAGALRAIVAGEVLKPASRE -RLTGWTIETRTGLRRLRAGLPADWRAGDKTGSFWGDKLNDIAIVWRPDRSPFFVTAYFES -PIALRPQDEAVLAQVGAIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio TaxID=662 RepID=UPI00046EFE68 --kDVSQKLETVSQRLVGRIGIAAQEIGSGERV-TVNGDETFVMASTYKVAIAVALLDRVD -KGELKLSDLIDISQDMMVADNAIAQNFVHPGLSVANLIEPMITESDNTATDICLKLAGGP -EAVTKKLRSIGITDQRVDRYVTEILRFEQEDLRDQSSPNAMLELLLAIDSGKALSETSSE -FLLNVMSRTRTGSGRLKGLLPKGTPVAHKTGTIG-GVANDVGFVTLPDGRRFAIAVYTKS -STTSDADRDRAIAEVSRTLYDFy ->[subseq from] class A beta-lactamase n=1 Tax=Yonghaparkia sp. Soil809 TaxID=1736417 RepID=UPI00138F8ACD ----VAAELAALETEYGATIGVLARDTSSGASI-AFGQDRRFGFASTMKAPLAGIFLDRVE ---GAARDEVVRWSAAQVEEYAPVTAERIAEGLTLAELAEAAVRQSDNLAFNLVLERLGGP -AALDAALAELGDETTEVVTLEPELNTIEPGSTDDTTTASALAGTIETLLLGPTLDVDDRA -LLLDWMSGNATGDTLIRAGAPEGWVVADKSGGAG-AIRNDVALVTRPEGAPIVIAVLTQR -DDPEADRDDSLVARAAEIALDAf ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas naejangsanensis TaxID=588932 RepID=UPI0004035731 -------DLSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTEPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL -EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTIQPAQSARNIERLILSEPLESAFKR -LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGEPIAIAVYFHA -TKSTDAQREAVVADATRQALK-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinomadura rifamycini TaxID=31962 RepID=UPI00047C969E --tALDETLAEIEKSRGVRIGAAGIDLATGKAV-GYRAGERFPFNSMFKVFACSAVLHKAR -TDPGLMDKVVRWTPGDMTGNSPETTEYTDTGMTPAQLCRAGITKSDGFAGNKLLDQIGGP -SGLTRFFRTNGDRVSRLDRPEPHLTEWEPGQVRDTTTPAAAARTFTGLTTGNALHPSDRA -RLVGWLKASLTGADRIKAGLPSDWTVGDKTGTGGHGTAGDIALVWSPGTEPMVLAVLTNR -TTDDTPHDDKAIAETATALA--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas subvibrioides (strain ATCC 15264 / DSM 4735 / LMG 14903 / NBRC 16000 / CB 81) TaxID=633149 RepID=D9QMV9_BRESC --------LSALEADNGGRIGFVAHDLGSGRRL-TARGDERFVYCSTFKMYLSAATLMRVQ -AGQERLDRAVPVTRADMVSHAPVTEPAIGSSLSVERLMQAVVEVSDNPGANLLLKALGGL -EAMRAFYRGIGDDSTTVDRFEPEMNRL--DGIKDTMTPARSVANLHRLFVDPTLSADSKT -MLLGWMFTSPTGTDRLKAGVPADWRVAHKTGTGGYGPTNDIGILYPPSGEPVIVAAYYHA -TRTSDSQNAAVIAQATRMAL--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3B8UMN7_9CAUL -------DMSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTRADMISHAPTTDPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL -EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALDSAFKR -LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGQPIAIAVYFHA -TKSTDAQREAVVADATRQALK-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MYSH2 TaxID=2303333 RepID=A0A372NYL1_9SPHI --tTLREQITELSKDAKGKVGVAMLDLKTGDTL-TINGKRPLVMQSTFKFPIAVAVLHKAD -KGLLKLDDKLHITKKDLPEYSPLRDKHPDGNITIRELLDYMLIWSDNDACDILLNRVCSK -AEVEKYMHQLGGLSFRIRATEDEMKHNWKAQFTDVCTLWDMANLLKTVRHGSALSAKNTD -YILTTMAKTEVGKKRIKGLLPEGTVVIHRTGTSATDATNDAGIINMPGGRQVILVVFVTD -SKADDDTREAVIARIAKAVYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY2B7 TaxID=2080571 RepID=UPI000CE7D440 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPDSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTSPGRDAVVLSILSAR -NDPEAEYDDALVARAAAVVL--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. MC1 TaxID=1174684 RepID=N9USN6_9SPHN ---SAANRIAALEKISGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK --NGVSLRTPLPFTRADLLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP -TAFTDHVQATGDLVTRLDRVEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDPAYRT -MLRDWLVKSETGLARIRAGLPRTWHVGDKTGTCGT-AYNDVAFVEEPGGDKYMIAVYLDR -PALKGDAANAIIADVARAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter sp. YU21-B TaxID=2695855 RepID=UPI0013225F6A ----LEAEIARLTAPIGGKVGVAAWQLDKGERI-MVNAGERFPMASTFKIAVAGAILASVD -AGRLQLDQLVAVQPNDIVPSDGIASLAIHPGLSVHNLLELMLTLSDNTATDVLTRLAGGP -QAVTGWVRKQGVEEQRIDRDTAGILRAFDKDVRDTSTPAAMGQLLTKIFNQQALSVSSTK -VLIDIMQRCHTGAGRLPGRMPAGTVIAHKTGTIG-GTVNDVGVMTLPDGSQIVIAVFIKE -SDKPMEQRERVIAEIARSVRDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter cryoconitis TaxID=188932 RepID=A0A327T396_9SPHI --nDLRKKLQAIVSSHAATIGFSLTDLQNGDTI-TVNGTKHLPMQSVYKFHLALAVLNQVD -QGKLKLDQKILVKKSDLLPWSPLREKYPNGEIPLSEILSYTVSQSDNNGCDILFRLMGGP -AKVNRYIHSLGIKQVAIVATEEQMHKDENVQFTNWTTPVAATELLKLFYSRKVLSKTSHD -FLWKVMTETVTGANKIKGLLPAGTLVAHKTGSSGTTGTNDIGIVTLPNGKHFAVAVFVSM -TKEDEKTNDLIIAELTKVSWDY- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium sp. S22 TaxID=2483794 RepID=A0A4Z0JWV4_9MICO --qEITADLKTLEQDFGARIGVSAVDTGDGSTI-DYRADERFGFASTLKVFAVAELLARTA ---DEELDERVTWTQADVDAWTPVTEKHVDTGLPLADVAESAVRVSDNAAMNIVLNEIGGP -QGLDEALEDAGDPTTEVIDGEPDLNDIEAGSSDNTTTPAAYTSDFQGLLDPDRLADGDRQ -VLLEWMSDNETGDFLIRAGAPEGWTVKDKSGRSD-AIQNDIAVVYPPDEDPIVITVFTES -DDSDSEEGPALIEAAAETVLGAf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia paucivorans TaxID=114259 RepID=UPI0002D8EFA9 ---ELDLALTELEDLYGVRLGVHAFAPRRELTY-TRRADERFALCATFMVYAVAALLRREQ -QGRLSLDDKARVEPDQVVENSPVTAPVQGRTMTLGELCAAALVHNDNTAANLLLGRLGGP -RAITEFARTLGDNATVLNRWAPDLNTVARGDPRDTTTPTGLATGYRELLFGSALAPARQR -VLTEWMAANVTSGERIRKGLPDGWTSADKTGAGGYGTVNDAGVVRAPNDDRLLLVLFSDS -TTSDAPNNDVPIAEATAAVVT-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3D5MH45_9CAUL -------DMSALEARHGGRLGVSVLT--EGKRA-DWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPTTAPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL -EPLRAFYRGIGDETTRVDRLEPELNRA--DGDKDTITPNQSVRNIERLILSEALDSAFKR -LLLEWMVASPTGQARLKAGVPSGWTVAHKTGTGGDGPVNDIGVLYPTDGQPIAIAVYFHA -TKSTDAQREAVVADATRQALK-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Adhaeribacter aquaticus TaxID=299567 RepID=UPI0003FC79A0 ---ALKRNIEDLIASKDATVGVAIYGLESKDAI-YINNNKHFPLQSVFKFHIALAVLSEVD -RGRLTLNQKIRIKKSDLLPWSPIREKYPQGNLPLTEVLKYTVAESDNNGCDILLRLIGGT -QFVNNYLHKLGIKEVSIQANEAEMHQAWDVQFQNWTTPKSTVDLLKLFQERKILSAKSYD -FLWQTMAETVSGKNRIKGQLPAGTVVAHKTGTSGTAAINDIGLVTLPNGTHFAISVLVSN -SKESTETNEKIIADITKLSWNYf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A7 TaxID=2080524 RepID=UPI000CE90DA3 ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Uncharacterized protein n=2 Tax=Pelomonas sp. Root1444 TaxID=1736464 RepID=A0A0Q7SM59_9BURK -------GFAALERRVGGRLGFFALDTGSGRTL-AHRADERFATASTFKILLAARVAHGVD -TGRWRWDDEVPLQASDRVAHAPAFDRLLPRGATLAELVQGIVVESDNPCANLLLRRCDAP -AGLTAWLREQGDTVTRLDRWELALNENAPGDPRDTSTPRAFATTLQHLLLGRGLKRASQA -RLWADMQASRTGLERLRAGVPADWRVLDKTGTGNRGAVNDVALVFPPHGAPWVVAAFQSG -SGAPTDDLSAVHADVMRRLVQTw ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. YR515 TaxID=1855316 RepID=A0A1I2IXD9_9MICO ---AVARTLADLEREYDATVGVVATDTTTGETV-AYNGDRRFGYASTLKAFAAAQFLRAVH ---GADRDERVRWSAADATAHSPVTSEHVADGLTIAQLAEAAVRQSDNLALNLVVDRIGGP -AGLDRALAELGDRTTEVVHDEPALNTIEPGSTEDTTTPAAFAAALATVLDGQTLGRSDTA -LLEHWMSGNATGDTLVRAGAPDGWTVVDKSGGAG-GIRNDVARVTRPDGGPIVIAVLTTR -NAPDTAYDDALVARSAAAALDAf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A3B9EDF2_9CAUL -------DLSALEARHGGRLGVSVAT--DGKQA-AWRGDERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTRADMISHAPVTEPAVGSTLTIEQLMKGAVEVSDNPAANILIREMGGL -EPLRAFYRGIGDESTRVDRLEPELNVA--DDDKDTITPDQSVKNIQRLLIDTPLDTASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNGPAIAIAVYFHA -TKSTDAQREAAVADATRQALK-- ->[subseq from] class A beta-lactamase n=2 Tax=Novosphingobium sp. PhB55 TaxID=2485106 RepID=UPI001066399A ---QAASDLEEIERQHGMSIGAVMRGSDGRIHF-AHRADERFRLCSTFKIFLAAEVYRQAA -TNPHLLQRPVTIRDTDRLGNSPVTARQQDGGLSAEMLCMAAVQYSDNSAANYLLDLVGGP -PAVTRLFRTLGDNISRLDRIEPALNLGAPEDLRDTTTPAAIAGSLGTLLLSTVLGDHQRA -TLLGWMRNEQNGTRRIRAGVPRGWTVANKPGTNDAGAVNDIAIIRPPSGGSFVLTVYTAS -AENRVTQSESVIAAIAGMA---- ->[subseq from] class A beta-lactamase n=1 Tax=Legionella pneumophila TaxID=446 RepID=UPI000770A238 ----AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMLVAAVALKNIE ------ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMRYSDNAATNILITRLGGT -KSINEFAKSIGDRSFNLENLEPNLNSD-PNNIHDSSTPKDMAQSVQKLLVNNVLGQENQN -ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGSV-ISNDIGIVWSPACKPIVLAIYTFS -NKKDAQKADKAIAETTKFILDEf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2H1K923_9MICO --qEITAQLEAVEDEYDARVGISAIDTGDGSSV-DYRSDERFGFASTLKVFAVAELLAGTS ---PEELDEVVTWTQADVDAWTPVTEKHVDTGLPLEDVAESALRVSDNAAMNIVLDEIGGP -QGLDAALEDAGDPTTEVIDEEPELNDIEPGSSDNTTTPAAYTADLQGLLDSERLSEDDRK -VLLEWMSDNETGDPLIRAGAPEGWTVKDKSGHSD-AIQNDIAFVYPPDEDPIVITVLTET -EDPESEDGPAIVEAAAEAVLGSf ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=Staphylococcaceae TaxID=90964 RepID=A0A0H3W0X3_STASA ---SHTQELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPND-------------- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis terrae subsp. terrae NBRC 15098 TaxID=1219058 RepID=A0A142W2H4_9SPHN ---SVANRIAALEKKSGGRLGVAVTDQFGKLIV-GHRADERFAMCSTFKLLLAAQTLTAAK --NGVSLRTPLPFTRAELLPYSPGAERLLDAEYRIGFAAEDAVVLSDNLAANLLLDHFGGP -TAFTDHVQATGDLVTRLDRMEPDLNANIPGDPRDTTSPAAMAKSAAAYIFGDKLDTAYRT -MLRDWLVKSETGLERIRAGLPRTWPVGDKTGSCGT-AYNDVAFVEEPGGDKYMIAVYLDR -PALKGDAANAIIADVARAVT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia contaminans TaxID=488447 RepID=A0A1E3FU98_9BURK ---TAQAELTALEKASNGRLGVAALDTSNGVRI-AHHARERFPLCGTYAVAAAAAMLARGS -LDASLLPRRILYRRYEIVAGSPITESHVDTGMTIEQLCVAMLQSGDKGAGNLLMGVLGGP -QAVTAFARASGDMSFRLDHWEPELNNAAPGDERDTSTPVEMVDTLQRLLLGNTLQEPQRT -QLMEWMVGGARGATGIAAGVPPGWRIADKAGTGGYGTTTDVAGLWAPSRAP--------- ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0240 TaxID=2487066 RepID=A0A3N0WPD3_9FLAO --tALEEKINSITKGKKATVGISVLGFEDHFKY-NKNGDRKLPTLSVFKFHIACAVLDFVD -KGKLSLDQRILFKKSDLLEWSPLLEKYPDGNLSLGEVIDYTVALSDNNGCDLLLRLIGGT -QTVQQFMDSKGVKGFRIKYNEDDMHKNWKTQYENYSTTNSVVDLLKKFYDGKILTKKSTD -YLMQIMLGTKTGANKIVEQLPKGTPVAHKTGSSGTVAENDMGIVTMPDGKHYAIAVFVSD -STETDSVNNKMVSDISKAVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Cellvibrio sp. PSBB006 TaxID=1987723 RepID=A0A1Y0FXT0_9GAMM ------ERLRALEVG-HARLGVCFLDTVTGEIS-GNRIEERFAMCSTFKLAMVAACLREAD -NGRLNLEEILPYSEADLLPWAPVTRKHLAKGLSIATLAQAAQEMSDGVAANLLVKRLGGP -NAVTTKFREMGDTVTRLDRYEPDLGLVLSADTRDTTSPLAYAELVRQILTGSILRRDSRE -QLLEWTRNTATGARRLRAGLPPEWRTGNKTGTGRTNKCNDVAITFPPSKNPIIIAAYFDS -GEKIEERHDAVLAEVGKIAAE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophagaceae bacterium PMP191F TaxID=1691979 RepID=UPI0006BBB2B2 ---NIRVAIANIAQAAQGKVGVAVMNLESGDTV-SLNGTVRFPMQSVFKFPIAMAVLHEVD -RGKLSLDKMIRVKKKDLMLWSPMLEKYTANEISISELLAYTVSQSDNNGCDILLKEIGGT -KKVNNYIRDLGVKGIAIKATEKEMHSAWNVQYNNWCEPIAMMQLLKIFYEGKTLLKTSND -LLWKLLVETSTGPNRLKGLLAKNITVAHKTGTSGTAATNDVGIIVLSATQHIAIAVFVSD -AEANESVRENVIAQIALLVSD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga oryziterrae TaxID=1031224 RepID=UPI0012F95307 ---SLRIKMGEIANTAKGTVGVAIIHLESRDTF-TLNGSLHYPMQSVYKMPLAIAVLHEVD -KGKLSLDQKIHIRKEELLPWSPIRKKYPEGNLPLREILGYTVSQSDNNGCDILFRLLGGT -ANVNKYIHSIGIDSIAIAATEEEMARTWNVQFTNWAEPGAILQLLDGIYKGKYLSKPSIS -VLKEMMEGTTTGPDRIRGILPENTVVAHKTGSSGTAATNDAGVITLPNGKHFAIVVFVCN -ATADEKRRDAVIAEITKVFWDHy ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_1_20CM_4_54_11 TaxID=1805408 RepID=A0A1Q7TP74_9BACT ---DAATRIAAVEARIGGRIGVAALDTGNTKHV-EHRADERFPMCSTFKFLAAAAVMKRVD -EKKEKLERFVPYGAKEILEYAPVTKEHLKDGMTLGALCAAAIEQSDNTAGNLLLDAIGGP -SGLTNFVRSLGDRVTRLDRIEPELNSAIPGDERDTTTPAAICSDIQRLLLGDAF------ ------------------------------------------------------------- ------------------------ ->[subseq from] DNA, contig: SP630 n=3 Tax=Sphingomonas TaxID=13687 RepID=A0A0C9MTH6_SPHPI -----TARLRAIERASGGRLGAFVLDTGSGRSF-GWRADERFCHCSTFKLSLAAMALREAD -AGRLDLMETLAFSRADIVAYSPIVEENLDKGLPILALAQAVQITSDNAAANVLMHRLGGP -AALTRFWREIGDAVSRLDGYEPAINVIPPGTQENSTTPRAMAETVRRIVLGDVLRPASRD -RLRSWMAATQSGSKRIRAGLPADWHGFDKTGTGMGNKTNDLAVLMPPKGSPLVVTGYFEN -PSDVRPADEAVLKMLGRLAV--- ->[subseq from] Serine hydrolase n=1 Tax=Vibrio vulnificus TaxID=672 RepID=A0A2S3S1I9_VIBVL ---DISPKIEKLSQGLVGRVGVAAQEIGSGASI-TVNGDQTFAMASTYKVAIAVTLLDRVD -KGQIKLSDLVDLPQQEMVVTNAIAETYVHPGFSVANLIEVMITESDNTATDVSLKLAGGP -EAVTKKLRSLGITEQRVDRATSEILRAFEKDPRDHSTPKAMLQLLLAIDSGKALSAKSSQ -FLLATMSRTSTGSGRLKGLLPKGTPVAHKTGTIG-GVANDVGFITLPDGRRFAIAVFTNS -STTSAADQDRAIAEISRTLYDFf ->[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI0011F3E107 ---TLQDQVKQYEKE-GWKVGLSILS-SDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTEFMRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGEVLSDASKA -QLKEWMVNNKVADNMLRASLPKRWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] Beta-lactamase n=1 Tax=Ignavibacteriales bacterium TaxID=2049428 RepID=A0A419F7D5_9BACT ---------LQIIEQAKGKVGVAVINLKTSDTL-TVRGNEYFPMQSVYKFPLALAVLDKVD -KGEISLDKKLFVSKSDLLPWSPLRDKYPDGNLSLDEILSNTVSLSDNNGCDILFRLMGGT -AIVDKYIHNLGIEDIDIAFTEEEMHKDWQVQYKNRSTPLAMAELLYRFYYEDFLSKSSKD -YLWRIMAATVTGPKRIKGLLTEGTVVAHKTGSSGEDATNDAGIVQLDDGSGFVIVVFVSD -AAADEETREKVIAQIAKTVYDAy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella sp. TaxID=576 RepID=A0A346M1B8_KLESP ------------------------------------------------------AVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVI---- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6WDF4_9SPHN ---------ADIEAATGGRMGIALVN-EEGRVLlGFNRAERFAMCSTFKAPLAAAVLMGAE -KKRYGMEGTLSVRQSDLLEYAPAVRANIARGMSIAELTQAVVEVSDNSAANILLPLVGGP -QGLTAFMREHGDEVTRLDRTEPSLNENAAGDERDTTSPEAMARLMADLLFADM-PQGPAG -QLRGWLQASTTGLKRIRAGLLPGWTAGDKTGTCGN-AYNDVGVLRAPDGRSYILAVYLDR -PTVPGPKAEAAIAQVTRAALA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=R4MR46_ECOLX -------------------------------------------MMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTVFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLGKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERG------------------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Lutibacter sp. HS1-25 TaxID=2485000 RepID=A0A4Q1IQR2_9FLAO --kSISEKIEKISNGLVGRIGAAAQDLSTGLTV-SINGDEPFVMASTYKVAIAVTIFRQVD -EGKLKLTDLVDCPSEKMVPPNPLVTYHPGVKLSIANLLEPMITDSDNSATDFLLEVAGGP -QVVTDMLRSIGITDFRVDRYVSEILRFEQEDPRDHTTPNAMLQLLLAIDNGTALSEKSRE -VLLGMMSRTTTGFHRLRGLLPKGTPVADKTGTIG-GVANDVGFITLPDGRRIAIAVYTKS -STTSEADREKAIAEVTRSIYDFf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. YR573 TaxID=1881040 RepID=A0A1I0PUX1_9BACT ---SLRIKIDKIANTAKGTVGVAMIHLESRDTF-TLNGNLHYPMQSVYKMPLAMAVLHEVD -KGKLSLDQKIHIRKEELLPWSPIKTKYPEGNLPLREILGYTVSQSDNNGCDILFRLLGGT -ANINKYVHRIGIDSIAIAATEEEMARAWGVQFTNWSTPGAILQLLDGIYKGKYLSKSSIA -VLKKMMQETTTGPGRIRGLLSENTVVAHKTGTSGTNATNDAGVITLPNGKHFAIVVFVCN -ATADEKTRDAVIAQITKVFWDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075M395_ECOLX -------------------------------------------MCSTXKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAV----------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chitinophaga sp. t5 TaxID=1461282 RepID=A0A0B5E9H0_9BACT ------------ARGMGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0P0CPI6_KLEPN --------------------------------------EGRFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWLFADK------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9B4W3_9SPHN --qDLAARISEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG -----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRLVQADRA -LLQEWLAQTTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGARYILAAYLDR -ADGSASDAEARLAEAARAIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Actinotalea caeni TaxID=1348467 RepID=UPI0012E14C43 ----VSAELGALEEELDARVGVSALDTGTGAVV-EHRAQERFGFASTIKVFAVAELLRRVP ---PAEREEHVTWTDADVAAYAPVTSAHPG-GLTLAQLAEAAVRESDNLATNLVLERIGGP -AGLTEALAALGDRSTRLVDVEPALNDVVPGEEANTTTPAAFTADLLAVLEPGYLTEADRD -LLLTWMSGNATGDALVRAGAPEGWEVQDKSGGAGP-MRNDVAVVTPPDGAPIVLTILTTR -NDPDAPWADELVARTAAVVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium pusillum TaxID=69373 RepID=UPI0011AB7C46 ---AVAKSLAALEHHYDATVGVVATDTTTGETV-SYNGDRRFGYASTLKAFAAAQFLRSVH ---GAARDERAHWTAEDVAAYSPVTEQHTSDGLTYSQLAEAAVRQSDNTALDLVLKRIGGP -KGLDDALTELGDATTEVVNDEPDLNTIEPASTEDTTTPAAFTADLAKVFDGRTLNATDTA -KLQDWMSGNATGDTLIRAGAPTGWTVADKSGGAG-GIRNDIARVTTTDGHDIVISVLTTK -NDPAAKYDDALVAESAKTVLPAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. t1 ZQ-2014 TaxID=1561000 RepID=A0A0B5E3C6_9PSED -------------RRMGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] CP254 BETA-LACTAMASE n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0000110576 --kNAAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPK------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Listeria aquatica FSL S10-1188 TaxID=1265818 RepID=W7B1Z1_9LIST ---SVSEKLEVLENKYNAKLGVYATD--GNEKI-KYHSRERFAYTSTYKAIISGLLLKNRT ---EEELQKTIFFSKEDLVDYSPITEQFVDKGMTLKEIIHAAVAYSDNTAGNLLLNEMGGT -KKFQKELRLIGDKTTISSRYETDLNSAIPGDIRDTTTPEAFGQDLKYLTDPKHLDSQALK -YFKQTLVDNTTGDNLIRAGVPDGYLVGDKTGAGSYGTRNDIAIIFKENSKPLVWTVFSKM -DKEDDSYNDQLIADVAKVLSEEf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. CF314 TaxID=1144316 RepID=J2K7P7_9FLAO --sALDQKINSIIKDKKGTVGVSVLGFENEFTY-NKNGDKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKIFVKKSDLLDWSPLREKYPAGNLPLSEIIDFTVAQSDNNGCDILLKLIGGT -STVQKFMDSKGVKGFQIKFNEEEMHKDWNAQYENYSTTGSIVQVLKKFYDGKLLSGKSTE -YLMKVMLGTKTGTNKLVEQLPKGTPVAHKTGSSGTGAENDMGIVTLPDGKHYAIAVFVSN -STETDAINCKIISDVSKTVWEYf ->[subseq from] Beta-lactamase n=2 Tax=Pedobacter bauzanensis TaxID=653929 RepID=A0A4R1LNQ8_9SPHI ----LRQQIEQILISKKATVGVAVFGFEKGDTL-SVNNQIHYPLQSVFKFHIALAVLDKVD -KGELSLNQKILIKKSDLLPWSPIRDDYPNGNLTIAKILEYTIAQSDNNGCDILLRLIGGA -EVVNNYIHKIGVKDFSIQVNEEDMHREWNIQFLNWTTPTSTIDVLRKFNTGNILSKESYD -FLWNTMVETKTGEKRIKGKLPTGTVVAHKTGTSGTAAINDVGIVVLPTGEKVAISVLVSN -SKESQEVNEEIIADVSKLVWDWf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=A0A561P723_9BACT -hpTLRQQIADIAGNISGKVGVYAQLLETNDTV-SFNRDQHFPMQSVYKFPVSMAVLQQVD -AGKVGLDQPVDINKTDLTTVSPLRDKYPDGNLTVRELLDYNVRKSDGSACDILFKLLGGP -EKVNAYVHGLGIRSINIATLEEAQKENLQVQYRNWSTPAAMVQLLKKFFQDPVLSDSSKE -HLLYLMTTSGPGAKRLKGLLPEGTEVAHKTGTSWTAANNDVGIITLPNGTHMAIAVFVSD -SKANDEERDATIAKIAKAVWDSw ->[subseq from] Class A beta-lactamase n=2 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7ILX8_9BACT --sSLRKAIQQIAQSSGGTVGVSIIHLERGDTL-SLNGTGHFPMLSVYKFPIAIALLNQIE -AGKFDLDTKWHVTKKELLSHSPIRDKYPQGNITIRELIENMVALSDNNACDIILRKLGGT -KVVENYFHHLGYKNIAIRATEEEMATEWSVQYQNWCEPVLMGRLLNDFYEGKLLNSAYTK -VLKDIMLSTSTAPNRLPGLLPKGTPIARKTGTSGTAATNDVGVITLPSGQHLVVAVFVMD -SKAETAVREQTIARIAKAAYDHy ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium iliopiscarium TaxID=56192 RepID=UPI0005D353E2 ---DIDQYLRDTEQQIQGQIGVAVIDTQNNTQW-NFNGSERFPMMSVFKTLACANVLYDVQ -HKALKLTDKIDVTKAGLINWNPITQNFVGGKMSLQSVCGAAMLMSDNYAANLALEKIGGP -QGLTAFLRTIGDNSTLLDHFEPKLNYVEKGAKNDTTTPIAMMNTVKKLLIGNVLNAENKA -QLQFWMTNNMVSDGLARAVLPQGWKIADRSGGGVNGSRTLTAMVWNKDHQPVFIGIFIAN -SKKTLPELNKVMVAISEKIFHQy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI0010BE0298 -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMQRNTTGDNLIRAGVPGGWEVADKT------------------------------ ------------------------ ->[subseq from] Beta-lactamase TEM-1 n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2L1K688_KLEPN ------------------------------------------------------------- --------------KNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Filimonas lacunae TaxID=477680 RepID=A0A173MBB3_9BACT --nTIHKEVSHIVATQHGKVGFYATVIETGDTA-SYNSNNKFPMQSVYKFPIAMAVLKQVD -EGKLSLQQQIHILPSDIMPHSPIREKYPQGNMTLDQIITYNVQESDGTACDVLLRILGGT -AKANAYIQKLGIKNINIATTEKAQQTNDMVQYKNWSTPKAMTTLLKQFYTKPILSAGSKA -YLLKLMIETPHGAQRLKGKLPAGTIVAHKTGTSGTRATNDAGIITLPNGNHIAITVFVSD -SEDSQEQREGTIAAVAQAAWNQw ->[subseq from] Uncharacterized protein n=2 Tax=Legionella TaxID=445 RepID=G9EPC1_9GAMM ----AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMLVAAVALKNIE ------ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMRYSDNAATNILITRLGGT -KSINEFAKSIGDRSFNLENLEPNLNSD-PNNIHDSSTPKDMAQSVQKLLENNVLGQENQN -ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGSV-ISNDIGIVWSPACKPIVLAIYTFS -NKKDAQKADKAIAETTKFILDEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3C4T7_9SPHN -----------------------------------HRAQERFAMASTFKWLLAAGVLKRCE --EGLNIDAVMYFTPSDLVATSPVTSAQIGAALSVEQLCDAIVTVSDNTAANLLLVPMFGP -EGLTRFLRESGDAHTRLDRQEPELNENKANDPRDTTVPHAMARTLRRLLTDEVLNADSRA -RLIGWMEKASTGLDRLRAGLPVGWRAGDKTGTGGNGAHNDCCIVWPPGRSPIVIASYLSE -SSAPNTDKAAAHAAIARIIVEEf ->[subseq from] Class A beta-lactamase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=A0A1Y0RUL5_9CYAN ---RLHSQIEQISRAAQGRVGVAITLLETGESV-ALKANEQFPMQSVYKLPIGMAVMHQVD -QGMLKLGQKVQVTRNDFVTHSPIRDNHPQGVLNVLDLLRFMVSESDGTACDVLLRLIGGP -QFVTKYLHELGINGIVVANTEKELGQNELVQYRNSATPESVIVLLSALHAGRGLRESSRA -LLLQLMTQTPTGPRRIKGLLPVGTVVAHKTGSSRTAATNDVGLVTLPNGRHIAVAVFVSD -SKADDSTREKVIAMVARAAWDYw ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudarthrobacter sp. NamE5 TaxID=2576839 RepID=A0A5C4INA2_9MICC ---HLDRSIAALESANGVTIGIAAGR--QGQTAyTYRGGDTFPMCSLFKTLAVARLLREHT -YDDEFWKRRIRFRDDQIVENSIICAADEDRDMSVEELAEAALRFSDNTAGNLLLELIGGP -LQIGAYARTLGAPSTRLDRWEPELNEALPGDLRDTSTPSDIHKLYEALLLGEALGTLGQA -RLRSWMLRNTTAGKRLGAAVPPGAELADKTGAGAYGVVNDAGVVWPDGRPPLTLAVMTKT -DDPDAVNNNAVLARVGQLVFA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC52_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPND-------------- ->[subseq from] Class A beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=I3NNU9_9BACT ----AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMVVAAAALKNIE ------ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMSYSDNAATNILITRLGGT -KSINEFAKSIGNASFYLENLEPNLNSD-PNNIHDSSTPKDMAQSVQKLLENNVLSQENQH -ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGS-GTSHDIGIVWSPACKPIVLAIYTFS -NKDNAQQADKAIAETTKFILDEf ->[subseq from] Beta-lactamase n=1 Tax=Providencia alcalifaciens TaxID=126385 RepID=A0A4V6P077_9GAMM ---TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSNSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSEVIRVLGSHIFDEy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium AOCarb3 TaxID=654974 RepID=D6MLV4_9BACT --kDVKDKIEQIIDRSNGNIGVGVFDFASGLTV-LINNAHQFPMQSVFKFPLGMAVLDMVD -RGKLKLDQQVYVSKNDLQPYSPLRDKFPDGNVTLADLLTYSVSLSDNNACDILFRLVGGT -QVVNDYIRGLGIKDMAIVATEMQMSKGWDVQFENYSTPEAMLDLLKVFQSGKKLSASSSG -FLWKIMTESPTGLKRIKGKLPSTAKVTHKTGTSGTAATNDVGIMTLPNGNQIAIVVFVSN -SEANETAREMVIADIAKVTWDEf ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Siphonobacter TaxID=2635712 RepID=A0A2N7BCP2_9BACT --sSLRKAIQQIAQSSGGTVGVSIIHLERGDTL-SLNGTGHFPMLSVYKFPIAIALLNQIE -AGKFDLDTKWHITKNELLPHSPLRDKYPQGNLTIRELMENMVALSDNNACDIILRKLGGT -KVVEAYFHRLGYKNMTIRATEEEMATEWSVQYQNWCEPVLMGRLLNDFYQGKRLNSAYTK -VLKDMMLSTSTAPNRLPGSLPKGTPIARKTGTSGTAATNDVGVITLPSGQHLIVAVFVMD -SKAETAVREQTIARIAKAAYDHy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Hymenobacter sp. Fur1 TaxID=2594794 RepID=A0A558BPJ7_9MICO ---ALQAEVARAVAGFAGTVGVAVQEVETGASA-QVNGQAHLPMQSVYKFPLALAVLHQVE -LGRLQLDQELLLRPADLLPWSPLRERYPAGNVPLREVLRYTVSESDNNGCDILFRLLGGP -AAVQAYVRSLGVADVHIAATEEEMHRREDVQYTNWATPAAMCQLFANFSRGRYLAPASRA -VLWQMLATSPSGLKRLRAGVPAGTEVAHKTGTSGTAATNDAGLLTLPNGQHVAVVVFVTN -ATAPEEASESLIAAVSRVVWRHf ->[subseq from] class A beta-lactamase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=UPI000B3C4623 ---RLHSQIEQISRAAQGRVGVAITLLETGESV-ALKANEQFPMQSVYKLPIGMAVMHQVD -QGMLKLGQKVQVTRNDFVTHSPIRDNHPQGVLNVLDLLRFMVSESDGTACDVLLRLIGGP -QFVTKYLHELGINGIVVANTEKELGQNELVQYRNSATPESVIVLLSALHAGRGLRESSRA -LLLQLMTQTPTGPRRIKGLLPVGTVVAHKTGSSRTAATNDVGLVTLPNGRHIAVAVFVSD -SKADDSTREKVIAMVARAAWDYw ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. 3J1 TaxID=861269 RepID=UPI000B8156FB ------KRISELEKSSEVTIGVVAGD-GTRARI-EHRADELFPMCSLFKTLLVAELLERHS -YDSAFWSKTITFTPDDIVVNSLITAADPDGQMTIDELADAALRYSDNTAGNLLLREVGGP -SGLTSTLRRVGAQWTRLDRWEPELNEATADDPRDTSTPREIHRLFSDALIGSRLDQLGRA -RLMSWMLQNQTTSTRIGAALPEGAELADKTGAGGYGVVNDAGVVFLENRA-VSLAILTRT -SDSSAVGNNDVVRDTARIVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus thuringiensis TaxID=1428 RepID=UPI000BFE76E1 -----NDSFAKLEKEFDAKLGIYALDTDTNQTA-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDVHDTSTPKALATSLQAFALGDVLSTEKRD -LLIDWMKRNNTGDNLIRAGVPGGWEVAD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 66-10 TaxID=1895848 RepID=A0A1M2ZGS8_9SPHN --qAVAAQVAALEKQIKGRVGVAFRLLETGESG-AVAGAERFPMASTYKVAIAGTLLSLVD -KGQMRLDRMIAVTQADVDQTGEVANRVVHPGLSVANLMELMLTQSNNTATDKILALAGGP -AAVTAWLRANGIAEMQVDRSVNDLLNAFEKDPRDTSAPVAMVDLLGKLLASPLLKPESRD -FLRSVMERCETGAARIKGLLPAGTTVAHKTGTIG-GSINDVGMITLPDRGHLLIAVYTKS -SSLPEAQRERAIAEISRSLFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardiopsis lucentensis TaxID=53441 RepID=UPI000A003F43 -----DAEFTRLEEEFGVRLGVHALDTGTGRTV-EFQADERFAHCSTYKVLAFGAVLDRTP ---VDGLDRVVTFSGADLVFHSPIAQERVSTGMTLRELGDAALRHSDNTAANLLLRELGGP -EGLTEALRGIGDEVTRVDRFAPGMAEAVPGDVRDSSTPRALATSLRAFALGEVLPEDRRD -VLVGMLRANTTGDDLIRAGAPEGWEVGDKTGACGYGTRHDI------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Citrobacter freundii TaxID=546 RepID=G3LSZ7_CITFR ------------------------------------------PMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5WJ47_9BURK -------RLQALESASGGRLGVAVQEAGRAAPW-GYRQDERFPMCSTFKLIAAAGVLAMSA -RDAGLLERRIAYTQADLVSYSPVTQKHVGDGMTVAGLCAAALQYSDNTAGNLLIRLLGGT -DAVTAYARGIGDSAFRLDRWETELNTAIPGDPRDTTTPAAMATSVQRLALGDALGAPQRA -QLVAWLRGNTTGATRIRAGV---------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1D5 TaxID=2080546 RepID=UPI000CE780BD ----VSAELAVLENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKSLAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter limnophilus TaxID=1932778 RepID=A0A437MFX8_9SPHI --qDLRSKIIYIATQINGVVSVSVTNLETGDTL-NYNGNSHMVMHSVMKLPIAMTVLHQVD -KGKLKFDQKIHITKADLPEYSPLRDKYPEGDIAVSQLLSYMVSLSDNDACDILLKVLGGT -ATVEKYVHSIGVKDISIKASEAQMASAWPVQYTNWCSAKAINQLLGIMYKGSALSKRSND -FLWKIMLETSTGPKRLKGLLPNDAKVVHKTGTSPAAATNDAGIMILPNGRHIAISVFITD -SYADNAKRESVIAQIAKAVWDEy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus intermedius TaxID=1285 RepID=A6MFN9_STAIN ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKVITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPND-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Providencia sp. wls1921 TaxID=2675153 RepID=UPI0012B57A5E ---TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFTIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSEVIRILGSHIFDEy ->[subseq from] class A beta-lactamase n=2 Tax=Morganellaceae TaxID=1903414 RepID=UPI0003E2A204 ---TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLNHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSEVIRILGSHIFDEy ->[subseq from] Beta-lactamase n=1 Tax=Cellulomonas bogoriensis 69B4 = DSM 16987 TaxID=1386082 RepID=A0A0A0C0J0_9CELL ---DVSAELQRLEEEFDARVGVSAVDTGTGTTV-EHRAQERFGFASTLKLFAAAELLRQVP ---VDQRDARVTWTQEDVRAYSPTAGQHVADGLTLAELAEAAVRESDNTAMNLVLRALGGP -EGMERALADLGDSTTRVVDVEPGINDADLASGANTTTPRAFTANLRALLEPQNLREEDLA -LLLDWMTGNATGDALVRAGAPAGWVVTDKSGGAG-GIRNDVAVVLPPGRDPVLVTILTEK -RAPGAAYDDALVSRTAATVLSAf ->[subseq from] Class A beta-lactamase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2D6GUS1_9RHOB -----HTAIAYMESQNGGRFGVSAVNLATGQTI-THRGDERFAMCSSFKWLLAALVLQRVQ -AGEEDLSRMIEFSEADMVMHAPITEPALGEGLSVEALCRGTVQTSDNPAANLLLRTLGGP -EGFTQILRDNGEMTTRLDRWEPMLNENAAGDPQDTSTPNAMVSLMGYYLFGGGLNAEYQT -LLKDWMIGATTGLARLRDGMDAPWIGGDKTGTSSNNQSNDVAFAYQPDADPILITSYLNV -ENPVGAETDELHATIGRQIM--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9I1_SHISO -------------------------------------------MMSTFKVLLCGAELSRVD -AEQEQLGRRIHYSQNDLVEYSPVTEKHLTAGMTVRKLCSAAITMSDTTAAKLILTTIRGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTPASRQ -QLIDWMEAVKVPGPLLRSALPAGWFIADNSGAGERGSRGIIAALGPDGKPSRIVVIYTTV -SQA-------------------- ->[subseq from] Beta-lactamase n=1 Tax=Ignavibacteriae bacterium HGW-Ignavibacteriae-2 TaxID=2013809 RepID=A0A2N1VRQ4_9BACT -----RTNIKNIINNTNGSVGTAIFNLENGDTL-TFNGEAHFPMQSVYKFPLALAVLNEID -KGAFSLEQKIYVSKNDLLPWSPLRDKYPNGNIAISELLTYTVSQSDNNGCDILFRLIGGP -AKVNEYVHSLGIEGINIVSTEEEMHKDGTLQYKNWTTPKAMGQLLIKFVKESIISTKSKD -FLWDVMASTVTGKGRIKGLLPEGTIVAHKTGSSGAAATNDVGIIKLPGGGDLVVVVLVSD -CKDDEKTRDKIIADIARLAWE-- ->[subseq from] Beta-lactamase n=1 Tax=Siphonobacter aquaeclarae TaxID=563176 RepID=A0A1G9Q6P3_9BACT ---SLRTELVRIAEASRGVTGIAVTQLETGDTL-SVRGREHFPMQSVFKFPLALAILDLAD -KGRLSLDKTVRVLPNDLVPYSPLREAYPNGNITIAELLRYSVSLSDNIACDLLFRELGGP -DKLEKYLRKLGLTGISVKATEAQMATGWNVQYTNWCEPKTMNDLLVRFFTGKILGTASTE -RLRKWMLDTPTGSARLKGRLPAGTPVVHKTGTSSTNATNDAGVITLPGGGHVAVTVFVSD -SSAGLKDREETIARVALAVYQHy ->[subseq from] class A beta-lactamase n=1 Tax=Roseibium sp. RKSG952 TaxID=2529384 RepID=UPI0012BCD603 ----LASAITNMEQREGARIGVSVLDTQSGDVF-NHRGDERFPLNSTFKAFACGALLQKAQ -NGGIDLDARRPVSEQEVVSWSPVTEKQIGAPLTFREHCKASLEWSDNTAANVVLEAVGGP -KAMTQVLRTFGDTTTRIDRFEPDANIQPEGEVRDTTTPKAALQSFKTFVADGVLSGGVHA -DYLDWMKSGQVTGALLRPHLPEAWEIADRSGAGRDKTRSVIAAIWPPESAPVYVAIYIDL -EAASMQRRNEMIAELAQTLFQ-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=A0A239Y773_9STAP ---RTKQDLKMIEDKYDANVGVYALNTATGEEI-KFNENKRFAYASTLKAISSALLLEKTP ---HNKLNKKIHISKKQIVSYSPILEKYIDKDITIKKLIEATMLYSDNTANNIIIDELGGY -KEMRKRLKKLNDSTTVLSRKEPDLNNYSPKNTSDTSTPQAFGKTLKKLVMDGDLSKDNKE -FLLKLMINNKNGDTLINAGAPKTFKVADKSGQATYGSRNDVAFVYPKGHKPIILVIFTNK -NNKDAKPNDKVVSDVAELVL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium sp. CRIBSB TaxID=2683264 RepID=UPI001412EC88 ------VDFSALEARHGGRLGLYAV--GDAGAV-EWRGGERFVYCSTFKMYLAAATLLRVQ -AGQEQLDRQIPITRADMINHAPVTEPAVGGSLSIEQLMKGTVEVSDNPAANLLLKALGGL -EAMQAFYRSLGDNSTRVDRFEPEMNRL-DGD-KDTITPQSVANMLRLFIRPDTLSADSKA -MLLGWMFTSPTGVGRIRAGVPAGWRVAHKTGTGGYGPTNDIGALYPPTGGPITIAIYYHG -VRASDEQNEAVIAEATRMTL--- ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium pusillum TaxID=69373 RepID=UPI00119D5CAA ---AVTGALAALEHEYDATVGVVATDTTTGDTV-SYRGDRRFGYASTIKVFAAAQFLRTVR ---GHARDARVHWTVDDVAAHSPVTGAHVADGLTLAQLAEAAVRQSDNTALNVVLEHIGGP -ASLGAALRDLGDRTTEVVHDEPALNMIEPGSTEDTTTAAASTASLARVLDGRTLGPADTA -LLEAWMSGNATGDTLVRAGAPTGWTVADKSGGAG-GIRDDVALVTRPDGDPIVISVLTTR -NQPGTPYDDALVAETAHAVLGAf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium daecheongense TaxID=192389 RepID=A0A3N0W4X7_9FLAO ----LEQKINTILKDKKATVGISVLGIENGFQY-QKNGEKKLPMQSVFKFHIACAVLELVD -KGRLSLDQKILVKKSDLLEWSPMRDKYPNGDLTLGEIIDYTVAMSDNNGCDILLRLIGGT -KTVQKFMDSKRVTGFQIKFNEEEMHKDWNAQYENYSTTHSIVQVLKKFYNGKLLSKKSTD -YLMNVMLGTKTGTNKMVEQLPKGTPVAHKTGASGTGAENDMGIVTLPNGKHFAIAVFVSN -STETDAVNCKIVSDVTKVVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas bogoriensis TaxID=301388 RepID=UPI00054CF24D ---DVSAELQRLEEEFDARVGVSAVDTGTGTTV-EHRAQERFGFASTLKLFAAAELLRQVP ---VDQRDARVTWTQEDVRAYSPTAGQHVADGLTLAELAEAAVRESDNTAMNLVLRALGGP -EGMERALADLGDSTTRVVDVEPGINDADLASGANTTTPRAFTANLRALLEPQNLREEDLA -LLLDWMTGNATGDALVRAGAPAGWVVTDKSGGAG-GIRNDVAVVLPPGRDPVLVTILTEK -RAPGAAYDDALVSRTAATVLSAf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. TaxID=239 RepID=A0A519STE9_FLASP ---NLQPTLQRIADKYTATIGFSALDLENGKIY-SVNGNKHLPMQSVYKFHLALAVLSQVD -QGTYKLDEKIHIKQSDLLPHSPLREKYPNGDISLAELLTYTVGQSDNNGCDILFRLLGGP -AKVNSFIHMLGVQHVEIVATEEEMHKNEKVQFTNWTTPDAAIQLLNMFYKKKILSEQLHA -FLWKVMTESASGPKKIKGQLPEGTLVAHKTGYSGTAASNDIGIVTMPNGKHFAIAAFISN -TKENEEVIDRIIAELTRAVWDEf ->[subseq from] Class A beta-lactamase n=1 Tax=Cellvibrio sp. PSBB023 TaxID=1945512 RepID=A0A1U9N8U3_9GAMM ---------------GQARLGVCFLDTVTGEVS-GNRIEERFAMCSSFKLAMVAACLREAD -NGRLSLDEILPYSAADLLPWAPVTREHLAKGLSIATLAQAAQEKSDGVAANLLVKRLGGP -KAVTAKFREMGDTVTRLDRYEPDLGLVLSADTRDTTSPLAYAQLVSRILTGSILRPDSRE -RLLEWARNTTTGARRLRAGLPTEWRTGNKTGTGRTNKCNDVAITFPPGKNPIIIAAYFDS -GEKIEARHEAVLAEVGKIAAE-- ->[subseq from] Beta-lactamase n=1 Tax=Curtobacterium sp. 314Chir4.1 TaxID=1279028 RepID=A0A285XX17_9MICO ---AVARSLAALEREYDATVGVVATDTTTGATI-SYNGDRRFGYASTLKAFAAAQFLRSVH ---GAARVERVHWTAADVTAHSPVTEQHIPDGLTYTELVDAAVRQSDNTALNLVLTRIGGP -KGLDDALAALGDTTTEVVNDEPDLNTIEPGSTEDTTTPAAFTADLARVFDGHTLNASDTA -QLRDWMSGNATGDTLIRAGAPTGWAVADKSGGAG-GIRNDIARVTTTDGNEITISVLTTK -HDPAAAYDDALVARSAAAVLRAf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0S1AYP8_9GAMM ---ALQAEAERLAAQLPGDVGAALVHLESGRAV-YLNADQPLPMASTMKVPVAVHILKLVD -EGKLSLQQQVLLGPEDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP -EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEILSPASTA -VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVAAVFIR -SRASSEARDAAIAQLARAAHDYy ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=root TaxID=1 RepID=A0A0B5E4A9_9BACT ---------------MGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. C-1 TaxID=262667 RepID=A0A0M8JGW8_9SPHN -----AKAIRDVERRSGGRLGIAVVD-ARGKLVsADRGHERFAMCSTFKLLLAGQVFERAA --EGVSLRTPLPFERGELVSYSPGTEKLIGPDQRLGFAARDAVVLSDNMAANLILEQIGGP -AAFTAALRRSGDAVTRLDRIEPDLNENAPGDERDTTSPIAMATSAAAYIYGSRLKPDHRT -QLRGWMIESATGLKRIRAGLPQGWIAGDKTGTCGT-AYNDVAFVETPGGRKYVIAIYLDR -PAVEGDVASAVIAEATRIVA--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Chryseobacterium TaxID=59732 RepID=A0A376DT02_9FLAO --sALEQKINAITEGKKATVGVSVLGFENNFKY-HKNGDKPLPTLSVFKFHIACAVLDLVD -KGKLSLDQNIFFKKEDMLPWSPIGKKYPEGNIPLGEVLDYTVAQSDNNGCDMLLKLIGGT -KTVQNFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVLVLKKFYDGKLLSKKSTD -YLMKIMIGTTTGTNKIVEQLPKNTPVAHKTGSSGYNAENDMGIITLPNGKHYAIAVFVSN -STETDAVNCKVVSDISKAVWDDf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A561J112_9BACT ---TLRKTIDSIATHSKAHIGVSALLLETGDTL-TYRGNDHYPMQSVYKFPISMAMLHQVD -LGKYKLDENITITNDDIMPHSPIREAHPHGGMTVREISRYNIQESDGTACDVLLRLLGGT -KKTDAYIKSLGVKGINIATTEKEQQQDDTTQYRNWATPVGMTQLYKVFYQGKVLSKQSYD -VLWKDMAGSFPGAKRIKGLLPAGTVVAHKTGTSGTAATNDSGIIILPNGKHLALAVFVSD -SKGSEAEREGWIAQISKAVYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=UPI001261CA0B ----VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEAFPMASTFKVAVAAVILTKVD -AGELALTTMVPVPKAFYVDSEVVADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTKLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma rigui TaxID=564064 RepID=UPI0009B051D2 ----LQTQIERLINGRKATVGVSIHEFGSQQTL-VINGDKQMPMQSVYKLHLALAVLNEVD -KGRFTLTQKMHVKKSDLIPHSPMGEDYPNGGLPLADIIRYMVADSDGSACDYLFRLLGGP -GKVNDFIHHLGITDVAIQNTEEMMQANWAVQYTNWTTPKAMLRLLELIYQRKILSPARHD -FLWKVMVGTTTGENRLKKLLPPGTVVAHKTGTSGTGAVNDVGFIALPNGRYMAISVFVMN -STESMETNERIIADIAKVAYDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A077D1U6_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVHYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIA------------------ ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3LMY0_9BURK -------QLRALEQNANGRLGAYVVDIERGTAF-GWRENERFTHASSFKMSLAAMLLAKAD -AGKIDLRETLHWTKEDMLSVSPVTTANLGKGLSVRDLARATLVTSDNTAANVLMRRFGGP -SELTAFWRSIGDKSSRLDRYEPELNVTPPGTDLDTTTPAAMAATTAAFVHGTILTADSRA -VLRAWMAEVKTGQDRIRSGFPTNWISGDKTGTGIKHIYVDLAFGGPGGRSPLIVTAYFEP -SRPMDRDAVAVLAAVGRIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=UPI00137604D6 ---ALQAEAERLAAQLPGDVGVALVHLQSGRAV-YLNADQPLPMASTMKVPVAVHILKLVD -EGKLGLQQQILLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP -EAVQQRMRALGVEGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEVLSPQSTR -VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGQVVAAVFIR -SRASTEARDAAIAQLARAAHDYf ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. IC4_254 TaxID=2714040 RepID=UPI00142271E4 ----VEVGLAALEESTGRRVGVYARDTGSGDTV-AYRADERFGYASTLKALAAGEVLAGQP ---ASVLDQPLTVLPEDVADHAPVTAGAAGTDLTIGALGAAAVTDSDNGALNVLLRHLGGP -AALQAALAARGDTTTLVDADEPGLNEFTPGDPARTSTPRALAEGLATYVLGDALDPGVRA -AYVGWLTASTTGLDAIRAGTPEGWTVGDKTGTAGYGSRNDLAVVWPPGREPIVLAVLTDH -PDEAAEPDDAVLAAAARVVLAAy ->[subseq from] Class A beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4RYB6_9BACT --eRLEREIARLAELAGGTVGVAAVHLETGRAV-YLNRTERFPMASAYKVPIAVELLTRVD -RGEVRLDSLIEIRPEDLHPGSGTLTSLFDDPLSVHNLLELMLLISDNSATDILLRLAGGA -EAVTARMRAVGAEGIRVDRPTSLLIGAFDADPRDTATPEAMARLLERIWRREILSAESTE -LLLDIMRRCETGEGRIKGMLPPWVEVAHKTGTIG-GTTNDVGIISLPDAGHVVTVVFIKE -SQRPIPERERAIAFIARAIYDDf ->[subseq from] Beta-lactamase n=1 Tax=Parapedobacter composti TaxID=623281 RepID=A0A1I1LXN7_9SPHI --qSIRQHIAQIIHSKNAVVGVAITSADGQDTL-SINGAKRFPMQSVFKFPIALAMLSEID -KGNFSLDQKVEIKKSELLPYSPIREAYPEGTLTIAEILQYTVSLSDNVGCDVLLRLLGEP -EAVERYLKAHNIKDISIKINEEIMQSDWESQFRNWTTPVEANRILQTYYEGNLLSPASHR -FIWDLMKGTETGRNRLKGRLPEGTVVAHKTGWSGTAAVNDVGVVFMPDGNHFYISVFVTA -SSEDMETNERIIADITKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. B18 TaxID=95614 RepID=UPI0003467E2E ---AVDRTLAGLEREYDATVGVVATDTTTGETV-AYGGDRRFGYASTLKVFAAAAFLRQVH ---GADRDERVRWTAADATAHTPVTSAHVADGLTLAQLAEAAVRQSDNLALNLVLDRIGGP -AGLGRALTELGDRTTEVVHDEPSLNTIEPGSTADTTTPAAFAADLATVLDGRTLGRSDTA -LLERWISGNATGDTLVRAGAPAGWTVADKSGGAG-GIRNDVARVTRPDGGPIVIAVLTAR -NEPDAAYDDALVARSARAVLAAf ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A2L0SPR8_9GAMM ---ALQAEAERLAAQLPGNVGVALVHLQSGRAV-YLNADQPLPMASTMKVPVAVHILKLVD -EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP -EAVQQRMRALGVEGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEVLSPQSTR -VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGQVVAAVFIR -SRASTEARDAAIAQLARAAHDYf ->[subseq from] class A beta-lactamase n=1 Tax=Providencia alcalifaciens TaxID=126385 RepID=UPI000D34483C ---TLQDQVKQYEKE-GWKVGLSII-FPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLSHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSEVIRVLGSHIFDEy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A0A246HKD6_STEMA ----VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD -AGELTLTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTKLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] Class A beta-lactamase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IFI9_9BACT ---PLQTQIEQLLQGKKATVGVGIYDFNTKQTV-FLNGDTHLPMQSVYKFHVALTVLKEVD -KGRFKLDQKMHVKKSDIVPHSPMGEDHPNADLPLSEIIRYMVAESDGSACDYLFRLLGGP -TNVNTFIHQLGIKEVAIRETEETMQANWDVQYTNWTTPAAMLDLLKLFYQQKILSKGSHD -FLWKVMTGTVTGENRLKKLLPAGTLVTHKTGTSGMGAVNDVGFIALPNGKHIAISVFVAN -STEGIDKNEQIIADIAKLAYDHf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter sp. HMWF019 TaxID=2056856 RepID=A0A2R7K4L4_9SPHI ----FRNKLNEIVKAHKATIGYSLLDLQNGDTV-TVNGAKHLPMQSVYKFHLALAVLHQVD -QGKLQLDQKILVRKQDLLPWSPLRDKYPAGNIPLSELLSFTVSQSDNNGCDILFRLMGGP -AKVQQYIRSLGVSEVAISATEEEMHRDDQMQFTNWSTARSATQLLAIFYAKPILSKSSAD -FLWKVMRETTTGPNKIKGLLPPATEVAHKTGNSGTAATNDIGIVTLPNGKHFAIAVFVSM -TTEDEKTTDRIIAELSKASWDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax sp. SLBN-42 TaxID=2572897 RepID=A0A542J8Y4_9MICO ---RMAAALAELEHAASVTIGVVAVAHGSPNAF-RYRAADRFPMCSLFKPLAAAALVQARG -YDDAYWNTPIRYAEADVVSDSLVLDSKRPREATPGELADAALRRSDNTAGNLLLRELGGP -AAITAFAASLGATDTRLDRWEPELNEALPGDPRDTTTPDDIARLYTALLLDDAAGVLASS -RLREWMLRNRTSDARMRAGLTPPYELADKTGGGAYGVVNDAGVLWRAGEPPVTVVIMTRT -DRADAVRNNAVVADATRIVV--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1A5 TaxID=2080523 RepID=UPI000CE87269 ----VSAELAALENEFDARIGVSAVDTGSGRRV-DHRADERFGFASSLKVLAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEETTATGLPLSQLAEAAVRRSDNTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSTEDTTTPAAFTADLAAVATGDVLSAEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSTR -NDPEA------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium linens TaxID=1703 RepID=UPI00111D431F --qRLEEQLKDLEDRYDARVGVSAFDTESDESV-DYRADERFGFASSLKVFAVAELLDRTS ---PKEIEKNVSWTQADVDEWTPVTQKHVDDGLPLDDVAESALRVSDNLAMNIVLDELGGP -EALDDALEKSGDMTTEVTDEEPELNDVEDGSRDNTTTPAAFTNDLHRLLDPQQLSDDDRR -VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAVVTPPDRHPIVISVMTET -DDPESEDGPALVSAVAEVVLDSf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga rupis TaxID=573321 RepID=A0A1H7RIZ0_9BACT ---ALRQKMEAIIAGKQAHIGISMLAIEDKDTL-SINAAHHYPMQSVFKFHLALLVLHKAD -QGKLSLSQRIHIKQSSLAKWSPLRDEHTAPELTIKELLSYTVSQSDNNGCDILFGLVGGP -AALNNYIHALGVKDINIVANEAQMHAAWDVQYNNWTTPIAATQLLQKFQTGNILSENSKA -LLWQLMATGVK-SNRLKGLLPADTDVAHKSGTSDTAAFNDIGIITLPNGKHIAMAVFVSD -SKEDEATNQRIISEIAKAAWDHy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter sp. TaxID=1882438 RepID=A0A3C1BCF4_9SPHI ----LRRQIAQIAKPVKGIVGVSILSLEGRDTL-TYNGKARLVMHSVMKFPIALTVLHLVD -TGKLSLTQMVHIKKRDLEKYSALRDKYPKGDLSISELLNYMVSLSDNSACDILLKLIGGP -QHVQAYLLQLGIRGIAVRASEADMASAWELQFANWAKPYEMTLLLDQFYSGKVLTKSSTG -FLYKLMTETTTGPNRIKGLLPAGTVVAHKTGTSGTDATNDVGIITLPNGKHIAIAVFVCN -STNDEATREGVIANIAKAAYDFy ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium kwangjuense TaxID=267125 RepID=A0A135WIU6_9FLAO --sSLEQKINSITTGKKATVGVSVLGFENNFKY-SKNGDKELPMLSVFKFHIGCAVLDLVD -KGKLSLDQKLFFKKEDMLEWSPIRDKYPDANLSLGEVLDYTVALSDNNGCDLLLKLIGGT -QTVQKFMDSKGVKGVQIKRNEDDMHKNWKTQYDNVSTPNSAVLVLKKFYDGKLLSKKSTD -YLMQIMLGTKTGTNKIVEQLPKSTPVAHKTGASGKGAENDIGIITLPNGKHYAIAVFVNN -STESDAVNCRMVSDISKAVWDDf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013CFA2BF --rQLQQQIEQLATAAQGTVGVAATLVETGESV-SLHGDQPFPMQSVYKMPIGMATLHLVD -QGKLSLEQKIRVSTADYISHSPIREKYPNGTLSLAELLRYAVSESDGSASDVLMRVVGGP -NVIMSYLKSLGIKDLIVLNTEREIGSDNAVQYKNWAKPAEAVALLRRLQEGRGLSKSSRA -FLLRLMTETETGLHRLKGQLPVGTVVAHKTGTSWTAATNDIGLVTLPNGQHIAIAVFVSD -AKADTDTREAVIANISRAVWDYw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WHV5_9BACT ---QLKKDIVESINSIKADVGVAILHLENGDTL-SFNGLHHFPMQSVYKFHLALAVLHAVD -QGKLSLDHETFIAKSDFIPWSPIADKYPEGDLTVSQLLSYTISQSDNNGCDILFRLVGGP -RKVDEYIKGLGIIDVAIANTEAEMHENPDLQFKNWTTPRAMVQLLSLFYQGKILASPTHN -LLVEMMEQTITGNKRIKGQLPQGTVVAHRTGMSGRAALNDVGIITLPNGKHIAVALFVSN -TRESIPASEELIAKISRIVFDYy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A498CPX0_9GAMM ----VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEAFPMASTFKVAVAAVILTKVD -AGELALTTMVPVPKAFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A649UHJ1_KLEPN ------EQIKISESQLAGRVGYVEMDLASGRTLaAWRASERFPLMSTFKVLLCGAVLARVD -AGDEQLDRRIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAGNLLLKSVGGP -AGLTAFLRQIGDNVTRLDRWETELNQALPGDVRDTTTPASMATTLRKLLTTPSLSARSQQ -QLLQWMVDDRV------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Legionella sp. km772 TaxID=2498111 RepID=A0A3S0W2K0_9GAMM ----AHAGVKQIETKYNVKIGVYAIDTNNGNSF-SYRQDERFPFQSTVKMLVVAVALKNIE ------ADERIKISSDDIVFWSPIVRLNLDRGMTIKELAEAAMRYSDNAATNILITRLGGT -KSINEFAKSIGDRSFNLENLEPNLNSD-PNNIHDSSTPKDMAESVQKLLENNVLGQENQN -ILKTWMMNNTTGYKKIRYGLPLGWSAAEKTGGGSV-ISNDIGIVWSPACKPIVLAIYTFS -NKKDAQKADKAIAETTKFILDEf ->[subseq from] Uncharacterized protein n=1 Tax=Legionella drancourtii LLAP12 TaxID=658187 RepID=G9EJ58_9GAMM -----DTKLQAIEHEHHLKIGIYALDTNSGRVI-TYHAHDRFPFQSTCKFIGVSALLASD- ---KTLLEKKVLINPKELLFWHPISGQYVNQKVPLKTLAEGAISYSDNTAINIIIRELGGL -GAINQFAQSIENSSFKMAHYEINLNSN-PQINEDTSTPKDMALSLKKIMLGDILTTPNKA -LLLDWMRNNTTGYNRIRAGVPLGWSVADKTGSGSYGIANDIGIVWSPVCKPVILSIFTVS -NQSDAKPSDAVIAQITKAAFEEf ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B2EWR4_KLEPN ------------------------------------------------------------- ----------------DLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter xanthus TaxID=1784712 RepID=A0A3A1P766_9SPHN ---AAASKLADIEQRSGGRLGVTLVDPEGQVLF-SHRGDERFAMCSTFKTLLAAKVLTGAD ---GLKLDDRLTIDPAAVEGHAPFTRSRLDAGMTVGEAAEHIVTVSDNAAANMLLDRVGGP -QGLTQWIRTLGDDVTRLDRRELELNENAAGDPRDTTAPLAFAETYRKVMNDEALGPAQRD -QLAGWLNASVTGLNRLRAGLPDGWRVGDKTGFCAAVEINDVAVFNPEGKGWYTLVFLLDR -PRETGAVVDALGAEVGALAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas TaxID=40323 RepID=UPI0008A5F171 ----VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD -AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVITLPDGSRFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=A0A178P2W8_STALE -----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP ---SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVIDELGGY -KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD -FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK -NNKDAKPNDKIVSEVAEEVLK-- ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=UPI0002D9E73F -----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP ---SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVIDELGGY -KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD -FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK -NNKDAKPNDKIVSEVAEEVLK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacterium sp. MG-1 TaxID=2586910 RepID=A0A5C4X406_9MICO ---RLEEQLKDLEDRYDARVGVSAFDTESDESV-DYRADERFGFASSLKVFAVAELLDRTS ---PKEIEKNVSWTQADVDEWTPVTQKHVDDGLPLDDVAESALRVSDNLAMNIVLDELGGP -EALDDALEKSGDMTTEVTDEEPELNDVEDGSRDNTTTPAAFTTDLHSLLDPQQLSDDDRR -VLFDWMSGNETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAVVTPPDRHPIVISVMTET -DDPESEDGPALVAAVAEVVLDSf ->[subseq from] Beta-lactamase n=1 Tax=Mucinivorans hirudinis TaxID=1433126 RepID=A0A060R6W8_9BACT --nSLHSKINEIVKDKRATVGVAICPIGGTDTV-SVNGAAHLPMQSVFKFHIALAVLDQVD -KGALSLNQKIKLTMADLLPWSPIRDKYKCGDLSVAELIQYTVAQSDNNGCDILLRLIGAT -EAVEHYLQRIGVDDVAIKANEEQMQMVWDVQYQNCTTPLSAVRLLSKFYAGGAVSAKSRT -FLYDVMVNTTTGAKRLKGLLPAGTVVAHKTGSSGTAAVNDIGIVILPDGSAYAIAVLVSD -SAEDSTTNEAIIARVSQAAWQYy ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas bacteroides TaxID=74311 RepID=UPI0004959F88 --------LSALEAREGGRLGFAAKDMGTGRML-AWRGEERFVYCSTFKMYLAAATLLRVQ -AGLERLDRMIPITRADMVNHAPVTEPAIGSSLSVEALMKGTVEVSDNPAANLLLQAMGGI -EPMQAFYRDLGDPTTRADRFEPEMNRL--DGEKDTVLPLQSVVNIQSLLIDTPLSADHKA -LLLKWMTDTPTGMARIKAGVPAGWTVAHKTGTGGYGPTNDIGVLYPPSGAPVIVAAYYHA -AC-DDPKNEGVIAEATRLAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Mucilaginibacter sp. MJ1a TaxID=2599294 RepID=A0A563U1Y4_9SPHI ----LKNKINEIAKDAKGEIGVSMIDLQTGRSF-SINGDKPLVMQSTFKLPIAVAVLHKVD -KGSIKLEDKLRLTKADLPEYSPLRDKHPDGNVTIRELLDYMLIWSDNDACDILLNKVCSK -AEVEQYMHQLGGTSFWIRATEMEMKNDWQAQFTDVCTVTDMAKLFRTVRNGKALSAKSTE -YIIKTMEKTEVGKKRIKGLLAANTVVAHRTGTSATDATNDGGIITLPNGKQFILVVFVSN -AKADTNTREAVIARIAKVVYD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. TaxID=1874826 RepID=A0A519QPB4_9SPHN ------ATLKRIEQAARGRLGAFVLDPASGRSF-GWREHERFAHCSSFKLSLAAMLLGRAD -KGEVDLGEILHWSKADMLSTSPVTSLHIADGLPVGELARATLVTSDNTAANVLLRRFGGP -EAVTRFWRSTGDTVSRLDRYEPELNLTPPGAELDTTTPAAMAATLAKLVLGEVLAPGSRN -TLREWMIAVATGRNRIRAGFPVDWVSGDKTGTGIRHTYVDLAFGGPAGASPVIVTAYFEP -ERPMDPASTGALAEVGRLA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L6C4A0_ECOLX ---------------------------------------------------AVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPL-------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A0B5E494_9GAMM --------------SVVARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium echinoideorum TaxID=1549648 RepID=UPI001186B213 ----LDQKINTIIKDKNATVGVAVLSIEDNFRY-NKNANKKLPMLSVFKFHIAAAVLDRVD -QGKLSLDQKIFITKKDLLEWSPIREKFPNGNMSLGEMIYYTVAWSDNNGCDILLRLIGGT -ETVQKLMDSKGVKNFRIKNNEEQMHKGIQYLYDNYTTPHSLAQLYKDFYLGKILSKKSTD -YLYNIMLNTETGTNKLKEQLPKK-TIAHKTGSSGKTAENDSGIVTLPNGKHYSIIVFISD -STEPEAVNCQMISDISKTVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus caeli TaxID=2201815 RepID=A0A1D4NPI3_9STAP ---STNNDIEKLEKKYGANIGMYALNTQNGEEL-SFNENKRFAYASTLKAISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITIKKLIEATMLFSDNTANNKIIDELGGY -EHVKNRLTDLGDTTTHPSRKEPDLNFYSPKDKRDTTTPIAYGKTLNKLIVDGKLSKANKD -FLLDLMFKNKSGDTLIRDGASSNFKVMDKSGQATYGSRNDVALVYPDGQKPIILVIFTNK -DKKDGKPNDKIVSEVAKIVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. BN140078 TaxID=2607653 RepID=A0A5B2VJB2_9BACT --qSLNARLQQIAATIKGKVGVSALLLETGQTA-ELNAQQHYPMQSVYKFPIALAILQQVD -KGKLQLNQPVQIAKAELIPHSPIRDNHPDGVMPLREVLRYNVTESDGTACDVLLRLLGGT -KATQKAIEALGIKDIAIATTEMVQVSDELVQYRNWSTPIAMTRLLRIFYTKEVLSPASKA -LLLKDMTETPVGPQRLKGLLPKGITVAHKTGTSGTRATNDAGIITLPDGRHLIITVYVSD -AHGTTAEKEGIIAKMAKACYDEw ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR33 TaxID=2035428 RepID=A0A2H6A5S6_9BACT --qRLERELARIAALTDGKVGLAALHLETGRAA-YLNPDEPFPMASTYKVPIAVELLTRVE -RGEVGLDTLIELRPQDLHPGSGTLTELFDDPLSLRNLLELMLLISDNSATDIVLRVAGGP -QAVTERMRRLGIDGIRVDRPTIQLIARFDQDPRDTATPRAMTSLLAKIWRGEALGDSATA -LLLDIMRRSTTGAGRIKGMLHPDVIVSHKTGTIG-GTTNDVGIITLPDGGHVALSVFIKG -STLTVEQRERVIAHLARAVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. LM091 TaxID=1904944 RepID=A0A1D8YE86_9GAMM ----VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD -AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Amniculibacterium aquaticum TaxID=2479858 RepID=UPI000F5A1475 ---DLQNKINQITSDKKALIGVSILNLDGREVA-SINGQEKLPMQSVYKFHIALAVLSEVD -RGRFSLDQKVDIKKSDWYPWSPMRDDNPEGGFTVAQLLEYAVSKSDNIACDELLKLLGSP -KNVDAYIKSQGIKNVSIKLTEKEMQATWDAMYENWTTPHAASEIAYKFYTKKLLSQKSHD -FLWKIMHETNTGENRLKGNLPNGTIVAHKTGTSGRKACNDMGIVMLPNGNYFVITVFVTQ -SKENDAENEKIIAEISKAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0007D6D126 ------------------------------------------------------------- -----QLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMGDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=UPI0007D8EC96 -----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFSYASTLKAVSSAMLLEKVP ---SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVIDELGGY -KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPSAFGKTLNKLIIDGNLSKSNKD -FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK -NNKDAKPNDKIVSEVAEEVLK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1L6C498_ECOLX ------------------------------------------------------AVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLIWV----- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI00141003A4 ---QLQTNIEQIIKNKKATVGVSIYESGSRQTL-IINGDKHMPMQSVYKFHLALAVLNEVD -KGRLKLSQKMHVRKSDIIPHSPMGEVYPNGELPLSDIIRYMVADSDGSACDYLFRLLGGP -KQVDAFIHQLGIRDVAIRDTEEMMQANWDVQYTNWTTPSAMLRLLKLFYQGKILSASSHD -FLWKVMVGTTTGQDRLKKLLTAGTVVAHKTGTSGTGAVNDVGYIVLPNGKYLIISVFVTN -STETIQTNEQIIADIAKSAYNHf ->[subseq from] Beta-lactamase (Fragment) n=8 Tax=Enterobacteriaceae TaxID=543 RepID=G3LSZ6_ECOLX ------------------------------------------AMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ ------------------------ ->[subseq from] Class A beta-lactamase n=2 Tax=Spirosoma montaniterrae TaxID=1178516 RepID=A0A1P9X4C7_9BACT --dALRQKLQQIISTKNAVVGVSIIANNGKDTL-SLHGNRHCPTQSVFKFHAALAVLDQID -KGKFSLDQKVAVQKKDLLPWSPLREENPDGGFAISKLIQYAVSQSDNVACDALLRLLGGP -QVVEGYIRENGIKDISLKFNEEDMQAQWDNMFQNWTTPIAASETLRKFYDNQLLSPKSYA -FIWRIMKETTTGEGRLKGLLPKGTIVAHKTGSSGTNATNDIGIVFLPNGNYFIISVFVAN -STENDQTNERIIAEIAKATWDHy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SAORIC-644 TaxID=1869314 RepID=A0A2K1DY47_9SPHN --qDLAARISEIEKASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAAMTLDTPG -----LREKRLHFGAGDILSYAPYAKERASFGMSGLEAAHHAVTLSDNTAANLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRLAQADRA -LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETSDGSRYILAAYLDR -ADGSASDAEARLAEAARAIAD-- ->[subseq from] Beta-lactamase n=4 Tax=Escherichia coli TaxID=562 RepID=Q9X6W1_ECOLX --dSLKSSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISIDKKLFVKKSELLPWSPLRDKYPDGNLSISEILKATVSRSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -YLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Uncharacterized protein n=1 Tax=Dyadobacter sp. 50-39 TaxID=1895756 RepID=A0A1Q3PLZ9_9BACT --aKLKSEIETISKQAKGIVGVGVMDLKTKGTL-LINQDHKFPMQSTFKFPLAIAVLDLVD -KGKYKLDQKIHVTREELDQHSPMRDKLPNRDITLGELISYSVSESDNNACDILFRLAGGT -RKVNDYIHSLGVKDIAIVATEREMKAGWEVQYTNYARPSAYLQLLQIAFERNKLSKASHD -FLWKVLVEGPTGLKRIKGLLPKGTEVAHKTGTSNTAATNDAGIMKLPNGKAIAVVVFVSD -AAADMDTRERVIAQVAKAAWDYy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Microvirga TaxID=2617746 RepID=UPI001378F8B1 ---TLAARIEALDRETSGRLGVGLVDLKDGSAW-SWRGDERFPMQSVYKLPIALAILTAVD -EGRLNLDDTIALGREDLSIWSPIAREFKGERYTVRQLAEHALQLSDNTASDTLLRLAGGP -GSVTALLYRHGIAGMRVDRSEREMQPAYLADVRDTTTPKAAAHLLAKLARGELLSEPMTR -IFLGILAGTRTGGSRIKAGVPEGSAVAHKTGTAMTGAVNDVGIVTLPSGRQIVVAVFVAG -SDRPPAERERLIASVTRAAIE-- ->[subseq from] Beta-lactamase n=2 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=A0A2Z5FTD0_9BACT -------------------------DGQSGLAF-GHRINDLFPMCSTFKVLAVAAALAQVD -SKRLDLRQTLSINPEDLLKYAPVTSQHLGLPMTLGDLCEAALTLSDNTAANLILRSIGGP -VQVTRFARLLDDSITRLDRAEPTLNEATPGDRRDTTTPLAMAKDLRKLFCGSVLSGASRS -LLKEWMIACKTGDKKIRSGFSKSFVIADKTGSGDHNTSNDVAVIWPANQSPLILTV---- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas humi TaxID=405444 RepID=A0A0R0C0C2_9GAMM ---GLQAEAQRLSALLPGQLGAAIVHLESGRSV-FLNADHPFPMASTMKVPVAVHILTLVD -EGKLSLQQQVTLGPDDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT -HAVNARMQALGISGMRVDRYIWELLAAWNEDPRDTSSARAMATLLQKVWRGEVLKPTSTQ -LLQEIMRDTRTGAARLRGMLPKDTPVAHKTGTVGD-VINDVGVITLPGGRGHAIVTVFVQ -SRASSEERDAAIAQLARAAHDYf ->[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter trehalosifermentans TaxID=1908263 RepID=A0A1V3IXX0_9PAST ---DWQQAITQQEQKLKANIGVALLAADGKVLF-EYQGHRPFPLNSTHKAFICGIALDLAD -NNGLSFTQKLPILPKEIVNYSPITQHK--TEMNLTALCSAAVSYSDNTAANLIVKQIGGI -KAVTDYFKRQGLNQTRLDRPEPDMNRDNLKKGLDLTTPIEAAQLLQQFTFGNLLSNSSKR -LFIQWMFDDQVANDLLRSTLPQGWKIADKTGAGSNGARSIISVFWKPDGTAYLLSVYLTN -TQATMAQRNQAIAEIGKTIFDH- ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter caricis DSM 15933 TaxID=1328867 RepID=A0A2T4UYR7_9MICO ---AVETALAALEAEYDARIGLVAVDTEDERTV-EHRADEQFRFASAIKALAAGALLARTE ---PADLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP -AGLQEALRALGDDVTRIDRIEPELNRVSPE-GLDTGTARSLAADLRALLLGDALHPVDRA -QLRDWMSGNATGDALVRAGAPDGWSVLDKSGGAG-GLRNDLAVVERPDAAPIVIAVLTER -SDPSLPYDDALVARAASVALE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. PAMC 26605 TaxID=1112214 RepID=UPI00026CA664 ------AALAALEQRHGGRLGVYALDLATGRAL-SHRAGERFKLMSSFKGLLSALMLYEVA -HGRDTLDAAVSFGASDLMDASPVTEANVTRGMTVRELCAAIMYRSDNAAANLLMRRVGGP -ARVTAFLRAIGDRVTRVDAYEGHLLDR--PLPADSSTPRAVTETMRRLMLGSVLSAADRR -QWEGWMAGNVVGRSRLRAAFPRAWTAGDRTGTAD-GICNDFAFARRPGTAPLLISAYYTA -PGLDMPAQEAVLRAVARRVV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A509IQL3_CITFR ------------------------------------------------------------- --------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWGPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Providencia sp. wls1919 TaxID=2675154 RepID=UPI0012B57A5D ---TLQEQVKQYEKE-GWKVGLSIL-FSNDKAI-SINGEQRFPLDSTVKSIACANALAKVD -AKKLSLSHSMIVTEENIVTYSPVAKDYMNKSFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSNSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASEYGVRGITSMVWSDNHEPVFISIYVRK -ADTSLDERSEVIRVLGSHIFDEy ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacterium iodinum ATCC 49514 TaxID=1255616 RepID=A0A2H1HPT7_9MICO -hqEVEDQLKDLEDRYDARVGVSAVDTGSDESV-DHRADERFGFASSLKVFAVAELLDRTT ---PKELEKNVTWTQADVDEWTPVTEKHVADGLPLEDVAESALRVSDNLAMNIVLDELGGS -KALDDALDRAGDTTTEVTDEEPELNDVEEGDTDNTTTPAAFTTDLLGLLDPQRLSDDDRK -VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSG-AIQNDIAVVTPHDREPTVISVMTET -DDPKSEDGPALVAAVAEVVLNEf ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas humi TaxID=405444 RepID=UPI00070D4F4B ---GLQAEAQRLSALLPGQLGAAIVHLESGRSV-FLNADHPFPMASTMKVPVAVHILTLVD -EGKLSLQQQVTLGPDDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT -HAVNARMQALGISGMRVDRYIWELLAAWNEDPRDTSSARAMATLLQKVWRGEVLKPTSTQ -LLQEIMRDTRTGAARLRGMLPKDTPVAHKTGTVGD-VINDVGVITLPGGRGHAIVTVFVQ -SRASSEERDAAIAQLARAAHDYf ->[subseq from] BlaZ-like penicillin-hydrolyzing class A beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=UPI0011CB8B96 -----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP ---SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKVFDELGGY -KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD -FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK -NNKDAKPNDKIVSEVAEEVLK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=A0A3D8Z8S0_STAPS -----------------AHIGVYALDTKSGKEV-KFNSDKRFAYASNSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD48_9BACT ---------------------------------------QRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSPH -TIERWLIGNQTGDATLRAGFPKDWVVGEKTGTCANGGRNDIGFFKAQERD-YAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Arcicella aurantiaca TaxID=591202 RepID=A0A316EG94_9BACT ---ILREKIATIIKSKNAKIGVSVLNLSNGDTL-TFNKTHHFPMQSVYKFHLALAILNQVD -KKKFSLNQPIFVSKADLRPWSPLRDKYPEGNIPLSEIIAYTVSQSDNNGCDRLFRLMGGA -IKANEYIHKIGVKDVNIVATEEEMQKDWQVQYTNWSTPAAATKLLQKFYQQGIMSKNSQD -FLWKVMVETTTGPNKIRGLLPKDATVAHKTGFSGTGATNDIGIVILPNGKALAIALFVSN -STETELTNDRIMADITKVVWDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Variovorax sp. s4p23 TaxID=1367569 RepID=A0A0B5E4A1_9BURK ---------------ADNRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma oryzae TaxID=1469603 RepID=A0A2T0RWT4_9BACT --qSLQEKIERVINGKKATVGVGIYDFGSRQTL-TINGDEHMPMQSVYKFHVALAILHEVD -KGRFKLTQKMRVKKSDLTPHSPMGEDYPNGVLPLSELIRYMVAESDGSACDYLFRLLGGP -KQVDTFIHGLGIRDVAIRETEAVMQANWDIQYANWTTPKAMLSLLTRFYQRNVLSPSSHD -FLWKTMVSTTTGENRLKKLLPAGTVVAHKTGTSAMGAVNDAGFIILPTGKCIAISVFVTN -STEGIATNEQIIADIARLAYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. AY1E1 TaxID=2080549 RepID=UPI000CE8E475 ----VSAELAVLENEFDARNGVSAVDTGSGRRV-DHRADERFGFASSLKALAAAEFLRTVP ---AAERDEVVTWTVADVEAYSPVTEESTATGLPLSQLAEAAVRRSDSTALNLVLRRLGGP -SALDRGLEALGDTTTEVVNEEPALNTIEPGSIDDTTTPAAFTADLVAVATGDVLSSEDRA -LLLDWMSGNATGDTLVRAGAPAGWSVADKSGGAG-GIRNDVAVVTPPGRDAVVLSILSSR -NDPEADYDDALVARAAAVVL--- ->[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter heidelbergensis TaxID=1908258 RepID=A0A1V3I7A2_9PAST ---DWQQAIHQQEQKLKADVGVALLS-EEGKILfEYQGHHHFPLNSTHKAFVCGMALDLSE -DNRLSFQEKLPIHATEIVSYSPITEHK--SSMNLTELCSAAVSYSDNTAANLIIKQLGGV -SAVTDYFKQVGLTQTRLDRTEPDMNYDNLKKGLDLTTPIEATQLLHQFIFGDRLNDNSKM -QLIQWMLDDQVANDLLRSTLPKGWKIADKTGAGTAGSRSIISVFWKPNGRAYLLSIYLTN -TQATMAERNQAIAEIGRVIFN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium carnipullorum TaxID=1124835 RepID=A0A1M7L010_9FLAO --sALEQKINAITEGKKATVGVSVLGFENNFKY-HKNGDKPLPTLSVFKFHIACAVLDLVD -KGKLSLDQNIFFKKEDMLPWSPIGKKYPEGNIPLEEVLDYTVAQSDNNGCDMLLKIIGGT -KTVQNFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVLVLKKFYDGKLLSKKSTD -YLMKIMIGTTTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPNGKHYAIAIFVSN -STETDAVNCKVVSDISKAVWDDf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium gambrini TaxID=373672 RepID=A0A1N7Q618_9FLAO --sSLETQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYVE -KGKLSLDQKVSLNQSNLHEWSPLREKYPNGGVPLSEIIEYTVAKSDNNGCDILLKLLGGT -QVVQKFMNAKGVKNFQIKYNEEAMHKDWNAQYENYTTMNSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGTNKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN -STETAEVNCRMISDISKTVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Gordonia effusa NBRC 100432 TaxID=1077974 RepID=H0R324_9ACTN ---AIEAQIRDAAAMSGAEIGVAAYDPATGATV-KVNSANRFPMLSTFKTYAVAEILRKHG --IGARLDARVRITSADIVVNSPVTSAAVGTSMSLQELCIAALTRSDNTAGNLLLRDLGGP -TSIATTARRLGDDQSSLTRIEPDLNSAAPGDFRDTTTPDGLLSGYRQLLDGGAG-QHIST -QLLEWMRATKTSDQRTRAGLPAGWTTADKTGSGDYGTTNAAGVILTPSGKRLYLVIMTRD -ARSDAPAFNALLARVTQLL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Agromyces sp. KACC 19306 TaxID=2592652 RepID=A0A5C1YAA7_9MICO -------ALRRLERETSVTIGVTAVVHGTERVF-RYRGGDRFPMCSLFKVLAAGALVRARG -YDDGYWTRAIPYTDADIVRDSIVLATKQPQQATPGELADAALRFSDNTAGNLLMRELGGP -AAITAFAAELGATATRLDRWEPDLNAAIPGDLRDTSTPDDIARMYEALLLDDAAGVLASS -RLREWMLRNATSGTRMRAGLTPPYELADKTGGGDYGVVNDAGVLWRPGRTPLTLAIMTRA -DRADAVRNDDVVARATRIVL--- ->[subseq from] Serine hydrolase n=1 Tax=Chamaesiphon polymorphus CCALA 037 TaxID=2107692 RepID=A0A2T1GN43_9CYAN --------------AAQGRVGVGVMDLNTGKSW-FYNGERRLPMQSVYKLPVGIVVLKQVD -AGKLSLDRPVTVSRQDFAPWSPIRQEITGDSYTVRELLERAVGVSDNTAVDVLIRLVGGP -ERVTATLRQMNIRGIRVDRLERQLQPRYLSDPRDTATPKETIDLLAKLQSRQLLSENSTA -LLLKIMTDSPTGQQRLKAGLPQGWSIAHKTGTGPGTATNDVGIITSHGK-QVAIAVFVAG -SKAPIAKREQIIAQVATTVVQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s1p23 TaxID=1367552 RepID=A0A0B5E3B3_9PSED -----------------ARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DAA75E4 -------------------MGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8PC51_9BACT --kKLRNEIEQITLAAKGRVGVAEVVLETGETV-SLNPHDHFPMQSVYKLPIGMAVMKQVD -AGKVRLDQKVRVTKDDFIGHSPIRDKYPNGTLTVNELMGWMLLESDGTASDVLMKLIGGP -ETIQAFLTELGIKDMIVLDTEKAFGQDHSLQFRNWATPEAAVVLLRALHERRGLSESSQG -LLLKYMTESRPGAKRLKGLLPAGTIVAHKTGTSGTAATNDIGIITLPNGRHLAIAVFVAD -SAADEATREGVIAKIAKAVWDKw ->[subseq from] Class A beta-lactamase n=1 Tax=Neokomagataea tanensis TaxID=661191 RepID=A0A4Y6VAA1_9PROT ---TFTEQLHQLEHNSGGKLGVCALDTRSGRQF-GWRMEERFCHCSTFKLSLAALTLRESD -AGRLNLQETLPIERKDIVAYSPIVEKNLDKGLSIFSLAEAIQTTSDNAAANILLSKLGGP -EAVTRFWRDIGDNTSRLDGYEPTINVIPPGTVLNSTTPKAMAATVQKIVLGNVLKPESRS -HLLTWMNSTTSGLKRIRASLPQGWTGYDKTGSGMGNKTNDLALLVPPDNSPLIVSAYFEN -PENIRQSDEDILKKVGEI----- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga parva TaxID=2169414 RepID=A0A2T7BEV4_9BACT --tSLHQQFQDIAAQAKGRVAVYAQVLETGDTA-SLNAHVHAPMQSVYKFPIAMAVLHTVD -QGKLKLDQPVHVTKADYIRHSPLRDAHPDGNVTVRELLRYNVAESDGSACDVLLHLLGGT -AAADKYIHSLGVKEISIATTEKVQTENERIQYRNWSTAAGLVQLLHIFYTGRKLSPSSQQ -LLMDLMVNSTPGAHRIKGQLPAGTVVAHKTGTSGTRATNDTGIITLPNGQHVLLAVLVTD -SRADEATREQVIAATAKAAFDHw ->[subseq from] Class A beta-lactamase n=2 Tax=Pedobacter cryoconitis TaxID=188932 RepID=A0A127V8V0_9SPHI --nDLRKRLQHIVSSHAATIGFSLIDLQNGDTI-TVNGAKHLPMQSVYKFHLALAILNQVD -KGKLRLDQKILVKKADLLPWSPLREKYPNGEIPLSEILSYTVSQSDNNGCDLLFRLMGGP -AKVNQYIHSLGIKQVAIVATEEQMHKDENVQFTNWTTPVAATDLLKLFYSQKILSKTSHD -FLWKVMTETVTGANKLKGLLPAGTLVAHKTGNSGTTATNDIGIVTLPNGKHFAVAVFVSM -TKEDEKASDLSIAELTKASWDY- ->[subseq from] Beta-lactamase n=1 Tax=Flavipsychrobacter stenotrophus TaxID=2077091 RepID=A0A2S7SS00_9BACT -htTLRQQLATIGNVHSGSIGISVRAIEDQDTL-TVNNSHHYPMQSTFKFPLALYVLHKVD -KGQLALDQKIHISKEELYRWSPLREKYPDGNITIAELLDYTVSKSDNNTCDILFKLVKGT -YPTNKYIHKLGVKDIDIVATELQMGKGWGVQYTNWTTPSAMTDLLYQLYTGKCLSPGSTQ -FLMKLMTESANSDKRIKGLLPAGTIVAHKTGTSNTAAVNDLGIITLPNGKHLAIAVYVSD -TKEKSTEAEHVIAEIAKAVYDEy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8F61 ---QLQTKIEQVIKSKKAIVGVGLYEFGSQQTI-TINGDKHMPMQSVYKFHVALAVLREVD -KGRLKLNQKMHVKKSDLVPHSPMGEAYPNGELPLADIIRYMVADSDGSACDYLFRLLGGP -RQVEAFIHQLGIQDVAIRNTEEMMQANWNVQYTNWTTPTAMLSLLKLVYKRKILSASSHD -FLWKVMVGTTTGENRLKKLLPAGTVVAHKTGTSGMGAVNDAGFIALPNGKYMAISVFVMN -STERIEMNERIIAEIAKVAYDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium elymi TaxID=395936 RepID=A0A3D9DPS7_9FLAO ----LEQKINSIIKDKKATVGVSVIGFENNFKY-NKNGDKPLPTLSVFKFHIACAVLDLVD -KGKLSLDQKLFFKKEDMLEWSPIREKYPDANLTLGEVLDYTVALSDNNGCDLLLKLIGGT -QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTMYENYSTTNSAVQVLKKFYDGTLLSKKSTD -YLMQIMLGTKTGTNKIIEQLPKGTPVAHKTGSSGKNAENDMGIITLPNGKRYAIAIFVSN -STETELVNCKIVSDISKAVWDDf ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas acidaminiphila TaxID=128780 RepID=A0A0R0DM61_9GAMM ---ALQAEAERLAAQLPGDVGAALVHLESGRAV-YLNADQPLPMASTMKVPVAVHILKLVD -EGKLGLQQQVLLGPEDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP -EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEILSPASTA -VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVAAVFIR -SRASSEARDAAIAQLARAAHDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Candidatus Magnetomorum sp. HK-1 TaxID=1509431 RepID=A0A0M9E142_9DELT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLI--------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=bacterium 336/3 TaxID=1664068 RepID=A0A0M9DP66_9BACT --qNIRQKIDSLLKTKKADVGIAIYDLQSKDTI-TWGNYRKYPMQSVYKFHLALAVLHQVD -KGKLSLEQKILVKKSDLLPWSPLREKYPQGNLPLSEIIHYTVAISDNNGCDILFRLLGGT -KKVHKYIKSLGIKEIAIKATEEEMHKEWDVQFTNWTTPLATVQLLEIFHQKNILSKTSQE -FLWKTMVETSTGLKRMKYLLPKNTIIAHKTGTSDNKAINDMGIIMLPNGNYIAVCVFVSN -SKEDFQTNEQIIADVTKMIWDE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterococcus faecalis TaxID=1351 RepID=Q47757_ENTFL -----AKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPND-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter endophyticus TaxID=1808508 RepID=UPI00135D4A49 ---EALAAIARVEQESGGRLGVALRANGGDLKL-SYRGDERFALCSTFKVLLAARVLQLRE --SHALENRNLTYDESDIAGWAPYAKEHLAEGMSVEAAAEYAVKQSDNTAANLLLDATGGP -SSLTRWFGRNGDSETRLDRNEPELNSNDAGDPRDTTTPEAISESFRRALFGNILDAEYRG -TLLGWMAESPFGTARLRAGMPQAWPKGSKTGTCAQGEVNDVAWFQTPDGEEYILAAYLDR -PAGDKADAERALAKVGRIAAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. Alg231-15 TaxID=1922222 RepID=UPI000D553974 -------QLAAIEQRIGGRLGVALMD-GNGSLImMHRGSERFAMCSTFKAPLASVLFAAHE -AGTVDMFEEFNLKPSDGVPYMPFVEKKLSEKVSLHELAGAAVMTSDNAAANLILKATGGP -EAFTKFVRANGDKITRLDRIEPELNENAPGDPRDTTSPEAMAGLMQKLLIEGAPLDIDKL -TLQKWMKESKTGASRIRAGLPKGWPVGNKTGTAPGGASNDMAIIWPSTAKPVILTVYTDR -PTASAQAVEAAMADVARVVI--- ->[subseq from] penicillin-hydrolyzing class A beta-lactamase BlaZ n=3 Tax=Staphylococcaceae TaxID=90964 RepID=UPI00066D6752 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKS------------------- ->[subseq from] Serine hydrolase n=1 Tax=Shinella sp. TaxID=1870904 RepID=A0A2W6SZR1_9RHIZ ----LQVEAQRLAAQLPGQLGAAIVHLESGRSV-YLDADRAFPMASTMKVPVAVHILKLVD -EGKLTLQQQVTLDEDDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT -TAVNARMQALGISGMRVDRYIWELLAAWNEDPRDTSTARAMATLLQKVWRGEVLQPGSTK -LLQDIMLDTRTGSARLRGMLPKETPVAHKTGTVGD-VINDVGVITLPGGRGHAIVTVFVQ -SRASSEDRDAAIAQLARAAHDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium shigense TaxID=297244 RepID=A0A1N7HYF0_9FLAO --sALEQKINAITEGKKATVGVSVLGFENNFKY-HKNGDKPLPTLSVFKFHIACAVLDLVD -KGKLSLDQNIFFKKEDMLPWSPIGKKYPEGNIPLGEVLDYTVAQSDNNGCDMLLKLIGGT -QTVQNFMDSKGVKGFQIKRNEDDMHKNWKTQYDNYSTPNSAVLVLKKFYDGKLISKKSTE -YLMKIMIGTTTGTNKIVEQLPKNTPVAHKTGSSGNGAENDMGIITLPNGKHYAIAVFVSN -STETDAVNCKVVSDISKAVWDDf ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium foliorum TaxID=104336 RepID=A0A4Y5YR97_9MICO ----VEKELVGLEQEYEASIGVVALDTATGESV-SYGGDRRFGFASTVKVFAAAEFLRSVH ---GPDRDELVRWTAEEAASHAPVTSQYVEGGLTYAQLAEAAVRFSDNAALNLILDRIGGP -AALDGALESLGDATTEVANDEPTLNTIEPGSTEDTTTAAAFTASLATILDGAALSTADKT -LLIDWMSDNRTGDALIRAGAPDGWTVADKSGGAG-AIRNDIALVTPPERDPIIITVLTSR -NDPEAAFDDTLVARAASVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Holophagales bacterium TaxID=2478486 RepID=A0A6B0XK47_9BACT ---HLGAEIERLAEASLGTVGVAAIHLESGRGV-LLNADDQFPMASTYKVPIAVEILAQVD -EGKRSLDDLITMQTSDHVATYGVLSDFFDTPLTIQNVLGLMLRISDNIATDLLFREAGGA -EAITGRMKAFGAEGIRVDRTTRALIATFNADPRDTATPRSMAALLRKIWKREILSEKSSA -LLIDIMARCQTGENRIPGALPPGTPVAHKTGTIGE-STNDVGVITLPGDGHVISVVFVKE -SRPSNAAMEPVIAEIARASYDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Holophagales bacterium TaxID=2478486 RepID=A0A6B0W3C0_9BACT ---HLGSEIERLAEASLGTVGVAAIHLESGRGV-LLNADERFPMASTYKVPIAVEILAQVD -EGKRSLDDLITMQTSDHVVTHGALSDFFDTPLTIQNVLGLMLRISDNIATDLLFREAGGA -EAITVRMKAFGAEGIRVDRTTRALIANWLGRD-DAT------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. OV715 TaxID=1500287 RepID=UPI0006473BD3 ----LEQKINSITEGKNATVGVSVLGFENNFKY-SKKGDHPLPTLSVFKFHIACAVLDLVD -QGKLSLDQKLFFKKEDMLEWSPIREKYPDANLPLSEVLDYTVALSDNNGCDVLLRLIGGP -QTVQKFMDSKGVKSFQIKHNEAEMHKSWKALYENYSTPNSAVQVLKKFYDGKLLSKKSTD -YLMQIMLGTKTGTNKIVEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAIAVFVND -SMETDDVNCKMVSDISKAVWDDf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter sp. L196 TaxID=1641870 RepID=UPI00131E7018 ----LRPQIAEIAKSAKGIVGVSVLGLEDRDTV-NYNGNARLVMESVMKFPIAMAVLHLVD -SGVLTLNQTIHIKKKDLPPYSPLRDKYPNGDVSINDLMSYMVSQSDDDACDILLEKLGGA -DQVEYYLHMIKVRGINIEASEEDMAKTPESQYTDWCKPKAIIQLLDTLYTGNVLKPASRD -YLNKLMVATTTGPNRIKGLLPAGTIVAHKTGTSGTNGTNDVGVITLPNGKHVAIAIFITN -STADEATRDLVIAKIAKAVYDN- ->[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis TaxID=165697 RepID=A0A0Q8RLM9_9SPHN ----LARAVTAIEQRSGGRLGVAVTDARGALLF-GHRADERFAMCSTFKLLLAGQVLAKAA --HGVSLRTPLRFVRADLVAYSPGTDKLLGPNQQLGFAAKDAVVLSDNSAANLILAHIGGP -AAFTAEIHRRGDQVTRLDRNEPTLNENAPGDVRDTTSPAAMVKSAAGYIYGDWLTAGHRD -TLRGWLIESETGLGRIRGGLPQGWLAGDKTGTCGT-AYNDVAFAEEPGGAKYMIAVYLDR -PAVKGDDANAVIADVARAVVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. HI0020 TaxID=1822223 RepID=UPI0012E769F8 ----LVDDLQDIERRFNGRLGAHIIDTENGANV-GWRENERFAHASSFKMSLAAMLLARSE -RWEVDLEERLHWSEEDILFVSPVTKANTATGLTVRELAAATQITSDNTAANVLLKRFGGP -SEVTRFWRSIGDDVSRLDRYEPELNDVPPGTSSDTTSPSAMARTVKRLIVGGALSLENRA -LLSRWMIATETGLERLRAGFPSDWIAGDKTGTAVVHTYVDLAFGGPEGHAPLIVAAYFEP -NEPQEPMDANALAAVGRI----- ->[subseq from] class A beta-lactamase n=1 Tax=Steroidobacter sp. JW-3 TaxID=2497877 RepID=UPI0013007C74 ---TLEAEIARVSQPIGGKVGVAAWKLDKGGQV-LVNAGDRYPMASTFKIAVAGAILAQVD -AGKLKLDQLVPVQPNDIVPSDGIATLHPGISLSVHNLLELMLTLSDNTATDVLTRLAGGP -QAATAWVRKQGIEDQRIDRDTAALLRAFDKDVRDTSTPTAMAQLLTRIFNQQTLSASSTK -VLIEIMQRCHTGAGRLLGRMPAGTVIAHKTGTIG-GTVNDVGVITLPDGGQVVIAVFIKE -SDKSMEEREKVIAEIARSVRDFy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A5C6LWQ7_9BACT -------------ATARGHVGVAMMSLESGDTM-TINGHDHFPMQSVFKVPLAIAVLDQVD -KGKLSLDQVIHITKKELLPWSPIREKYPEGTMKLRELLTYTVSQSDNNGCDILFNLVGGT -AYVEQYIHGLGIDSIAIKANEERMAQAWKVQYTNWSSPLAMLQLLKGIHTGKYLSKSSNE -FLLKIMKETTTGPKRMRGMLPADAVVAHKTGSSDTAATNDAGIVTLPDGSHVAIVVFVSD -T---------------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s2p31 TaxID=1367557 RepID=A0A0B5E9G0_9PSED -----------TERASGTEVSYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas pruni TaxID=40683 RepID=UPI000A077C0F ------ADLRALERRAQGRLGAYVLDPVRRVWF-GWRANERFAHCSSFKMSLAAMLLAKAD -RKEVDLAEVLHWTKAEMLSVSPVTETRIDTGLAVEDLAHAIVVTSDNTAANVLLRRFGGP -EQLTRFWRSIGDNVSRLDRYEPELNVTPPGTELDTTTPAAMAATTAALVHGKILSPASRA -KFMAWMREVRTGRDRIRSGFPAGWDSGDKTGTGIKHTYVDLAFGGPAGRTPLIVAAYFEP -ARPMDPVATGALAEVGRIAV--- ->[subseq from] Class A beta-lactamase n=1 Tax=Burkholderiales bacterium TaxID=1891238 RepID=A0A3S0FGV0_9BURK ----VRPELALLEPSVSGRLGFFAMDTGSGRTW-AHRADERFAMASTFKLLLAARVAEGVD -RGRWRWDDTVPLLATDRVPHAPAFDRLLPHGATLADLVQGLLVESDNPCANLLLRRCESP -AGLTAWLRTQGDDVTRLDRWETELNDNAPGDLRDTSTPRAFARSLQHLLLGPGLARASQA -RLWADMQASTTGLARLHAGVPAGWRVLDKTGTGGRGAVNDVGLVFPPGGAPWVVVALQSD -STAGTAALSAVVAGALRQLVKAw ->[subseq from] Class A beta-lactamase n=1 Tax=Mucilaginibacter sp. PPCGB 2223 TaxID=1886027 RepID=A0A1C2GQ64_9SPHI ---SLRNIIATIAQDAKGTVGFCMMNVETRDTL-SYNGRLHMPMQSVMKFPIAITVLNDID -EGRFTLDEKVHIEKDDLKPYSPLRDKFPQGNISIRELLSYMVSLSDNNACDILLKEIGGT -AHVENFMHSFGVKNIAVKATEFQMAQGWDVQYTNWTTAFEMARLLDIANKPNFLSKESHA -YLWKIMQETSTGPKQIKGLLPAGTIVAHKTGRSGTAATNDVGIITLPNGKHLVIAIFVSN -STVDLPTREDVMARITKAAWDY- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas rhizophila TaxID=216778 RepID=A0A3N1KEN5_9GAMM ----VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEGFPMASTFKVAVAAVILSKVD -AGELALTTMVPVPKAFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVR--- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MYb238 TaxID=2040281 RepID=UPI001290C41A ---ALQAEAERLAAQLPGDVGAALVHLESGRAV-YVDADRPLPMASTMKVPVAVHILKLVD -EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILIRTGGGP -EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGELLSPASTR -VLQQIMLDTRTGNARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHIVAAVFIR -SRASTEARDAAIAQLARAAHDYy ->[subseq from] class A beta-lactamase n=1 Tax=Gordonia effusa TaxID=263908 RepID=UPI00058AFAC0 ---AIEAQIRDAAAMSGAEIGVAAYDPATGATV-KVNSANRFPMLSTFKTYAVAEILRKHG --IGARLDARVRITSADIVVNSPVTSAAVGTSMSLQELCIAALTRSDNTAGNLLLRDLGGP -TSIATTARRLGDDQSSLTRIEPDLNSAAPGDFRDTTTPDGLLSGYRQLLDGGAG-QHIST -QLLEWMRATKTSDQRTRAGLPAGWTTADKTGSGDYGTTNAAGVILTPSGKRLYLVIMTRD -ARSDAPAFNALLARVTQLL---- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. 357 TaxID=2555782 RepID=A0A3R8ZBN2_9CAUL -------DLSALEARHGGRLGVSVAT--EGLRA-AWRGDERFVYCSTFKMYLAAAILLRVQ -AGQERLDRAIPVTQADMIFHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPELNVA--EGDKDTITPDQSVRNIQRLLVDTPLSPESKA -LLMRWLVDSPSGPGRIKAGAPAGWTVAHKTGTGGGGPVNDIGLILPPNSAPIAIAVYFHA -TKSTNAQREAVIADATRQALK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JA02_9BACT ---RLEQEVARLAPLAGGTVGVAAVHLESGREV-YFNRVEPFPMASTYKVPIAVQLLTRVD -QGEVRLDSLIALTPADLHPGSGTLTELFDDPLSLRNLLELMLLISDNSATDIVLRTAGGP -AAVTARMRALGFDGIRVDRPTAQLIARFNADPRDTATPETMARLLTRIWRKEILRPATSD -LLLDIMLRSTTGAERIKGLLPPDTPVSHKTGTIG-GTTNDVGIVTLPGDGHVVTVVFVKA -SDKEIPERERAIAHIARTIHDYf ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=Q0PH70_SALTM -----------------------------------------FAMCSTSKVMAAAAVLKQSE -SDKTLLNQRVEIKKSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPTSWVVGDKTGSGDYGTTN--------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Holophagales bacterium TaxID=2478486 RepID=A0A6B1GP73_9BACT ---HLGSEIERLAEASLGTVGVAAIHLESGRGV-LLNADERFPMASTYKVPIAVEILAQVD -AGKRSLDDLITMQTSDHVVTYGALSDFFDTPLTIQNVLGLMLRISDNIATDLLFREAGGA -EAITARMKASGVEGIRVDRTTRALIASFNSDPRDTATPRAMAALLRKIWKREILSEQSSA -LLIDIMARCETGENRIPGALPPGTPVAHKTGTIGE-STNDVGVITLPGDGHVISVVFVKE -SRPSNAAMEPVIAEIARASHDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D4Y823_9SPHN --qDLAARISEIEKASGGRLGLGLHSPDKGLVY-AYRGDERFAMCSTFKLALAAMTLDTPG -----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRHAQADRA -LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR -ADGSASDAEARLAEAARAIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00085C0BEE -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINKQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKSAKPDDKIIAAVTEEAIK-- ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=K8DVY7_STAXY ---STNNDIEKLEKKYGANIGMYALNTQNSEAL-SFNENKRFAYASTLKAISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITIKKLIEATMLFSDNTANNKIIDELGGY -EHVKNRLTDLGDTTTHPSRKEPDLNFYSPKDKRDTTTPMAYGKSLNKLIVDGNLSKANKD -LLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVALVYPDGQKPIILVIFTNK -DKKDGKPNDKIVSEVAEIVLK-- ->[subseq from] Amo2 n=1 Tax=uncultured bacterium AOAmox2 TaxID=654971 RepID=D6MLV1_9BACT --hDLRKSIQDIIRASGENVAVAIMGLEDKDTL-SVNGRIHCPMQSVYKLPLGMAVLKQVD -LGKLSLDQKIHITKKDLLPWSPLQKKYPEGNVPLSEILMYTVSQSDNSGCDILFRLLGGP -SNVEKYIHSLGVRGMAIATTEEEMHGDWNVQFSNWSEPVAMVQLLQLVHEDEVLSPSSND -FLLKLMTETTTGPNRIKGLLPKDAKVAHKTGTSGTAAINDAGIVTLPNGKHYAIAVFMLN -SRSDPKKLEAVIAAIAKSAWDHy ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Pelomonas TaxID=2638132 RepID=A0A0Q8GT19_9BURK ----TSAGFAALERRVQGRLGFFAIDTGSGRTL-GHRADERMAMASTFKILLAALVAEGVQ -AGRWGWNDAVPLREDERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDTP -AGLTAWLRQQGDAVTRLDRWELALNENAPGDPRDTSTPRAFARTLQHLLLGSGLSRASQA -RLWADLQASRTGLKRLRAGVPAGWRVIDKTGTGYRGSVNDVALVFPPNGSPWVVVALQSD -STEPTDDLSAVHAEAMRQLVKAw ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides speluncae TaxID=2670337 RepID=UPI000D68B132 ------DAIAEIEQRHDRRIGLYAVNLRTGREL-AHRPDERFAMCSTFKTLAVAAVLALVT -PDPHVLGRRAYYPPSMVTGYAARMQVWQEQGPTVAEVCEAAQSDSDNAAANWLLQQLGGP -DAITRLARELGDSVTTLTRWEPELNAWEPGQQIDTTTPRAMGGSYVELLLGRTLDGPDRR -RLTRWMLASRTGGAALRAGLPAGWRIAEKTGSGAYGTRNDVGIAWTDGDVPILISCLTRS -TEPGAPTVDAPLADVARHCA--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=A0A0K2JNF9_9STAP --nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKKITLKKLIEATMLVSDNTANNKIIDELGGY -EQVKTRLIDLGDSTTHPSRKEPNLNYYSPKDKRDTSTPLAYGKTLKKLISDGNLSKANKD -FLLDLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYLDGQKPIILVIFTNK -DRKDGKPNDKIVSEVAEIVLK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Pasteurella sp. WM03 TaxID=2558280 RepID=A0A4Y9H1S2_9PAST ---DWKQTITQQEQKLKADIGVALLSSDGEVLF-EYQGNRAFPLNSTHKAFICGIALDLAE -DNALSFTQKLPIQATDIVSYSPITKN--KTTMNLAELCSAAVSYSDNTAANLIVKQIGGV -KAVSDYFKQHGLNKTRLDRREPEMNRDNLQKGLDLTTPIEAARLLHQFVFTDLLTAPSKM -LLTQWMLDDQVANDLLRSTLPEGWKIADKTGAGSHGSRSIISIFWKPDGTGYLLSIYLTN -TRATMAQRNQAIAEIGRVIFEQ- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A0U2ZT72_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNRRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A355YAL8_9GAMM ---ALQAEAERLAAQLPGDVGAALVHLESGRAV-YVDGDRPLPMASTMKVPVAVHILKLVD -EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILIRTGGGP -EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGDLLSPESTR -VLQQIMLDTRTGNARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHIVAAVFIR -SRASTEARDAAIAQLARAAHDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium camelliae TaxID=1265445 RepID=UPI000C1C8539 --dNLKEKIQQIISSKDAEVGVAIKSQDGKDTL-SINGNRHFPLQSVFKFHIALAVLSQVD -KGKFSLNQKIKIGKKDLLPYSPIRDQYPNGVLPLSKILEYTVSQSDNVGCELLLKMIGGP -EAVEKYCKESGVKDISIKINEETQQANWDLQFQNWTTPKAGNEILELFYVNQLLSKKSYD -FIWKVMRETETGENRLRGQLPKTTVVAHKTGSSGTAAVNDMGIVFLPNGKHYFITVFVTK -SMENAETNEKIIADISKAAWDYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0U3AZA5_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKESDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWU6_9BACT ------------------------------------------------------------- -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAAQA -TLTQWLEGNEVGGPLLRAGIPDDWRIGDRTGAGGHGSRSVVAILWPPSQAPLIAAIYLTQ -SDASMEQRNAAIAAIGAALAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=A0A561HSZ8_9SPHN ---TAAAALGRIEARAKGRLGAYVYDPARDRGF-GWRDEERFAHCSSFKLSLAAMMLAKGQ -RGEIDLDQLLHWSKADLLLHSPVTAEHVASGLTVRDLAHATLVTSDNAAANVLLSKFGGP -AELTRFWRGLGDSVSRLDRLEPELNTVPEGTELDTTTPAAMARTVAKLVLGHTLNPQNRQ -TLKDWMIEVETGRDRLRAGFPAGWIAGDKTGTGIRHTYVDLAFGGPAGRTPLFVAAYFEP -ANPMDPAALSALADVGRVAA--- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519LCR2_9CAUL -------DFSELESRNGGRIGFAALRAGERPLV--WRVDERFVYCSTFKMYLAAATLLRVQ -AGHERLDRAIPITRADMLNHAPTTEPAIGSTLTVQQLMQGTVELSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRL--DGDKDTISPLQSVANIRHLLVDTPLSPASKT -LLTRWMIDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPTNDIGVLTPPSGDPVVMAVYYHA -DRSSSDQNEAVIAEATRLALK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC46_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DN--------------------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBP5_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000852B928 -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKELNKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQQLGDHVSDPQRLEPKLNEYDPISTADTTTPRAAAQTLNELLTSHQMNTKNLK -LLKRVMIENETGDQLIKAGVPKDYLVGDKSGQGTYATRNDIAFIYPKDDKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter jiangsuensis TaxID=1591085 RepID=A0A2P8FWX1_9BACT ---KLKFEIEDISRQAKGIVGVGVMDLKTKETL-LINQNHKFPMQSTFKFPLAIAVLNLVD -KGKLKLDQKIHVVRAELDQHSPMRDKHSKQDITIGELLSYSVSESDNNACDMLFELAGGT -KKVNDYIHSLGVKDIAIVATEKEMKAGWNVQYTNFARPSAYLQLLEIVYQGRTLSKSSHD -FLWKILVAGPTGLKRIKGLLPEGTVVAHKTGTSATAATNDVGIIKLQNKRDIAVVVFVSD -ATAKADTRELVIAQIAKAAADYy ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter mallensis TaxID=652787 RepID=A0A1H1R942_9SPHI ----LRDKIVELAKPAKGIVGVSVLGLEDRDTL-NYNGNSRLVMQSVMKFPIAMAVLHLVD -SGLFTLDKTIHIKKKDLPKYSPLRDKYPDGDVSLRDLLSYMVSQSDNDACDILLKFLGGP -DQVEYYLQNAKVRGINIEASEEDMAKKWEVQYTNWCKPRDMVKLIDVFYTGKALLPASKD -FLYTIMTETTTGPKRIKGLLPAGTVVAHKTGSSGTNATNDVGVITLPNGKHVAIAIFITN -STADEATRESVIANIAKAVYD-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A5P5ZSA5_9FLAO --qSLRTELENIIRGKKATVGVAVHKLDGSFNM-EINGKTRQPMQSVFKFHIALAVLDAVD -KGNLKLDQEIFIAEKDLLKWSPIRNKYPDGNLPLKEIIRYTVAESDNNGCDLLLRLIGGT -ESVQRFMDDKGITDFSIKANEEEMHRDWNVQYANYTTARSMNQVLKQFTLGKIVSPESTH -FLMNVMLNTKTGLNKIKEQLPPGTPVAHKTGSSGTGAENDAGIITLPSGEQYTLSVFVSD -SMETDAVNCRLISDLSKKVWQHf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0009C1A468 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKIIAAAAKEAIK-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBU7_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=UPI0011BE0008 ---TAAAALGRIEARAKGRLGAYVYDPARDRGF-GWRDEERFAHCSSFKLSLAAMMLAKGQ -RGEIDLDQLLHWSKADLLLHSPVTAEHVASGLTVRDLAHATLVTSDNAAANVLLSKFGGP -AELTRFWRGLGDSVSRLDRLEPELNTVPEGTELDTTTPAAMARTVAKLVLGHTLNPQNRQ -TLKDWMIEVETGRDRLRAGFPAGWIAGDKTGTGIRHTYVDLAFGGPAGRTPLFVAAYFEP -ANPMDPAALSALADVGRVAA--- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium gallinarum TaxID=1324352 RepID=A0A0G3M9J5_9FLAO --tTLEQKINAITKDKKATVGISVLGFENHFKY-SKNGEAKLPTLSVFKFHIACAVLNLVD -QGKLSLDQKIFIKKTDLPEWSPIREKYPDGNLSLNEVIDYTVALSDNNGCDLLLRLIGGT -QTVQQFMDSKGVKGFRIKHNEDDMHKNWKNQYGNYSTTNSAVQLLKKFYDGKILSRPSTD -YLMQIMLGTKTGTNKIVEQLPKGTPVAHKTGASGTVAENDMGIITLPDGKHYAIAVFVNN -SYESDVINCKIISDISKAVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=UPI00061B18C1 ----VETEVARLATLIDGKVGVSAWRLDKGEQV-HLNPDEGFPMASTFKVAVAAVILTKVD -AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGP -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRSMSTLLTRLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] class A beta-lactamase n=1 Tax=Legionella pneumophila TaxID=446 RepID=UPI0013751DC1 ----IDNKLQAIEREYHLKIGIYALDTNSGHVI-TYHANDRFPFQSTCKFIGVSALLASD- ---KSLLEKQVSISPKELLFWHPISGQYVNQKVSLRTLAEGAISYSDNTAINIIIRELGGL -GAINQFAHNIGNSSFKIAHYEVNLNSN-PKINEDSSTPKDMALSIKKIMLEDVLNNQNKV -LLLDWMRNNTTGYNRIRASVPLGWSVADKTGSGSYGIANDIGIVWSPACKPVILSIFTVS -NQSDAKPSDAVIAQITKAAFEEf ->[subseq from] Uncharacterized protein n=1 Tax=Agromyces aureus TaxID=453304 RepID=A0A191WG56_9MICO -hdRMSRELRSLERATSVTIGVHAVTQGERRSF-RYRAADRFPMCSLFKVLAAGALVQARG -YDEAYWATPIPFTDADVVRDSAVLATLQPQQATPEQLADAAIRFSDNTAGNLLLRELGGP -GAVTAFAASLGAGRTRLDRWEPELNDAVPGDVRDTTTPDDIALLYSALLLEDAAGVLASS -RLREWMLRTATSGARMRAGLTPPYELADKTGGGEYGVVNDAGVLWRPGREPLTLVILTRT -DRADAVRNNEVVAEATRIVV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Variovorax sp. p5 TaxID=1461284 RepID=A0A0B5EAU0_9BURK -----------------TRVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WJV7_9BACT --nELQKEIEQIAAAAKGRVGVEAVVLETGETA-SMNADAHFPMQSVYKFPIAMTALAQVD -AGRLKLEQKVRVEKSDFVRRSPVRDQNPQGVLSLMELLRYAVSESDGTASDVVLRVVGGA -DVVNKYLSDLQVSGLVVLNTEKEIGRDWETQYRNWASPEGAVSLLRALYDRRGLSEQSRA -LLLKLMTETPTGLKRLKGLLPKDAVVAHKTGTSGNAATNDIGIITLPNGRHLVIAVFVSD -SPADEATREGVIAKIARAAWD-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00136413D0 ------------------------------------------------------------- -----------------LVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Shewanella aestuarii TaxID=1028752 RepID=UPI001425C2D8 --kDVSAKLETISQKLVGRLGLAAQEIGSDERI-TVNGDEKFVMASTYKVAIAVALLERID -KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP -EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSAQSSE -FLIDVMSRTRTGAGRLKALLPKGTPVAHKTGTIG-GVANDVGFITLPDGRRFAIVVYTKS -STTSEAERDRAIAEVTRILFDFy ->[subseq from] class A beta-lactamase n=1 Tax=Alphaproteobacteria TaxID=28211 RepID=UPI000829A4B3 ----LAAELRIIEAAGNGTLGVEIFNTATGASV-GINQDRRFGHASSFKFSLAALLLQRHA -AGTIDADRHVTWTEADMLSHAPFTRERLASGATLRELARATQTTSDNPAANILLRNLGGP -AGLTAFWRSLGDEVSRLDRFEPEMNVVPEAEFRDTTTPAAMARTVAKIVYGDVLPEKERA -ELKSWMVETETGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEPPTGAPLTFACYFRA -RQTELASGQETLARVGRII---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=G5D8T4_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QIN--------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Chryseobacterium sp. (strain P1-3) TaxID=1517683 RepID=A0A086F9Y6_CHRP1 --tTLEQKINAITKDKKATVGISVLGFENHFKY-SKNGEAKLPTLSVFKFHIACAVLNLVD -QGKLSLDQKIFIKKTDLPEWSPIREKYPDGNLSLNEVIDYTVALSDNNGCDLLLRLIGGT -QTVQQFMDSKGVKGFRIKHNEDDMHKNWKNQYGNYSTTNSAVQLLKKFYDGKILSRPSTD -YLMQIMLGTKTGTNKIVEQLPKGTPVAHKTGASGTVAENDMGIITLPDGKHYAIAVFVNN -SYESDVINCKIISDVSKAVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xixiisoli TaxID=1476466 RepID=UPI00137202ED ------DALAELERQADGRLGAFIVDPARGQGF-GWREDERFSMCSTFKLSLAAMVLAMAD -HGELDPLHTLYWSKSDLVPHSPATEPALADGMTALDLARATLVLSDNTAANVLLREYGGP -AAMTRFWRAMGDDVSRLDRFETELNDTPPNTDYDTSTPAAMARTVSRLLLGAVLSPTARA -TLRQWMMAIETGLDRIRAGFPAGWIAGDKTGTGFRHTYGDLAFGGPSGATPLIIAAWFEP -SARIEPRDPGAIATLARV----- ->[subseq from] Beta-lactamase n=1 Tax=Dietzia timorensis TaxID=499555 RepID=A0A173LPD3_9ACTN --qDLTARIVHMIDASEADVGVFAQSLDTRETV-EIGADESYPMLSTFKVYAVAAFLDRFG --TSAALDDTVTIAEPDLVDNSPVTSENVGRPMSYRDLAIAALTRSDNTAGNLLLRKIGGP -AEIGEFAGRVGDSASRLDRWEVELNEATPGDERDSTTARGLAAGYRAVLDGDVLTPEARD -LLVGWMGETETSDKLSRAELPEGWTTADKSGGGYYGTRNTAGLVLGPEGQRILLVVLSRD -GKRDGPYAEQLISGIAA------ ->[subseq from] class A beta-lactamase n=1 Tax=Providencia sp. wls1914 TaxID=2675156 RepID=UPI0012B5D02E ---TLQEQVKQYEKE-GWKVGLSIL-FSNDKAI-SINGEQRFPLDSTVKSIACANALAKVD -AKKLLLSHSMIVTEENIVTYSPVAKDYMNKSFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSNSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASEYGVRGITSMVWSDNHEPVFISIYVRK -ADTSLDERSEVIRVLGSHIFDEy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pelomonas sp. HMWF004 TaxID=2056841 RepID=A0A2R7SRT3_9BURK -------ALLELERRAGGRLGVAVLDTVSGTQT-GLRRDERFGMCSTFKLPLAGLVLKAVD -EGRLALDQWVPYGEKDMVSHAPVTSQQLKAGMTVGALAEATQVTSDNPAANLLITLLGGP -AAITASLRALGDAHTRLDRMEPEMNGVPDGELRDTTTPAAMARTTARLLQSDWLSAASRE -RLAGWMVATQTGRKRLRAGLPTAWRAGDKTGTA--------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces aureus TaxID=453304 RepID=UPI000832757D -hdRMSRELRSLERATSVTIGVHAVTQGERRSF-RYRAADRFPMCSLFKVLAAGALVQARG -YDEAYWATPIPFTDADVVRDSAVLATLQPQQATPEQLADAAIRFSDNTAGNLLLRELGGP -GAVTAFAASLGAGRTRLDRWEPELNDAVPGDVRDTTTPDDIALLYSALLLEDAAGVLASS -RLREWMLRTATSGARMRAGLTPPYELADKTGGGEYGVVNDAGVLWRPGREPLTLVILTRT -DRADAVRNNEVVAEATRIVV--- ->[subseq from] Uncharacterized protein n=1 Tax=Rhizobium oryzae TaxID=464029 RepID=A0A1Q9B1C9_9RHIZ ------ARLRAAERKAGVRLGAFVLDTERGRSF-GWRADERFCHCSTFKFSLAALALREAD -AGRLDPAEMLAFSRRDIIAYSPVVEDHLAAGLSILALAEAVQVTSDNAAANILMRRLGGP -EALTRFWREIGDDKSRLDGYEPAINIIPVGTEENSTTPRAMAGTVQRIVLGDVLSAESRQ -RLRAWMSATKTGLTRLRGGIPATWQGLDKTGTGMRRKTNDLAVLFPPGGKPLVIAAYVEN -PAETRPQDEALLRTLAELAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1E9505 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0004F6752E -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D529A -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D2E14 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAAAAEEAIK-- ->[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter genomosp. 1 TaxID=1908264 RepID=A0A1V3J9P0_9PAST ---DWKQTITQQEQKLKADIGVALLSSDGKVLF-EYQGNRAFPLNSTHKAFICGIALDLAE -DNALSFTQKLPIQATDIVSYSPVTKN--KTTMNLAELCSAAVSYSDNTAANLIVKQIGGV -KAISDYFKQHGLNKTRLDRREPEMNRDNLQKGLDLTTPIEAARLLHQFVFTDLLTAPSKM -LLTQWMLDDQVANDLLRSTLPEGWKIADKTGAGSHGSRSIISIFWKPDGTGYLLSIYLTN -TRATMAQRNQAIAEIGRVIFEQ- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. OV279 TaxID=1500285 RepID=A0A1M4YM06_9FLAO ----LEQKINSITEGKNATVGVSVLGFENNFKY-SKKGGHPLPTLSVFKFHIACAVLDLVD -QGKLSLDQKLFIKKEDMLEWSPIREKYPDANLTLSEVLDYTVALSDNNGCDVLLRLIGGP -QTVQKFMDSKGVKGFQIKHNEAEMHKSWKALYENYSTPNSAIQVLKKFYDGKLLSKKSTD -YLMQIMLGTKTGTNKIVEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAIAVFVND -SMETDAVNCKMVSDISKAVWDDf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A173DSP5_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDGQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Legionella pneumophila TaxID=446 RepID=A0A2S6F4X4_LEGPN ------NKLQAIEREHHLKVGLYALDTNSGHVI-TYHANDRFPFQSTCKFIGVSALLASD- ---KPLLEKKVSVSSKELIFWSPISGQYVNQKVPLKTLAAGAISYSDNTAINIIIRELGGL -GSINQFAHHIGNSSFKIAHYEVNLNSN-PKINEDTSTPKDMALSIKKIMLEDVLTNQNKA -LLLDWMRNNTTGYNRIRAGVPLGWSVADKTGSGSYGIANDIGIVWSPACKPVVLSIFTVS -NQSNAKSSDEAIAQITKAAFEEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Salmonella typhimurium TaxID=90371 RepID=A0A385JC04_SALTM -----------------------------------------FAMCSTSKVMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTT---------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1D9551 -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKELNKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQQLGDHVSDPQRLEPKLNEYDPISTADTTTPRAAAHTLNELLTSHQMNTKNLK -LLKRVMIENETGDQLIKAGVPKDYLVGDKSGQGTYATRNDIAFIYPKDDKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. Ery1 TaxID=2306995 RepID=A0A418NE88_9SPHN --------LRIIEAQGNGTLGVAVLDTGTGRVW-GHADYARFPHLSSFKLSLAALVLHLDE -TGALDAGEHVTWTEDDLLSYAPFAKERLEEGATLRELAEFTQKLSDNTAANVLLRRLGGP -ERLTAFWRAIGDETSRLDRYEPELNLVPPGEIKDTTTPTAMARTLGKLLYGDALGEAARA -TLKLWMAETRTGTKRVRAGLPPEWPSGDKTGTSLGSVYVDVGYVEPPARAPLTFAAYFRA -ARAADPASEAVLAEVGRVIAR-- ->[subseq from] Beta-lactamase n=2 Tax=Serratia marcescens TaxID=615 RepID=A0A0B6VPP7_SERMA --dSLKNSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLQPWSPLKDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. BLS98 TaxID=885586 RepID=A0A0J7I778_9FLAO --sALEQKINSITEDKKATVGISVLGFENNFRL-SKNGDKPLPTLSVFKFHIACAVLDLVD -QGKLSLEQKLFFKKEDMLEWSPIREKYPEASLSLGEVLDYTVALSDNNGCDLLLKLIGGT -QTVQKFMDSKGVKGFQIKRNEDDMHKNWKTQYDNFSTANSAVQVLKKFYDGKLLSKKSTD -YLMQIMLGTKTGTNKIVEQLPKNTPVAHKTGASGNGAENDMGIVTLPDGKHYAIAIFVNN -SIETDEVNCRIVSDISKAVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000406CC41 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAIYTNQ -DQKNAKPDDKIIAAAAKEAIK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WSB9_9BACT ----LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGDLRFPMASVYKLPIALRLLQRID -RGELRLDDPITLSTHDFRPHSPIAEFANNKPLPLERLLELMLGESDNSASDLLLRLAGGP -AAVTNRMQALGIMGINVSRPEGQLILAYADDPRDTSTPDAMADLLVRIHRRDVLEPASME -RLLQITTATQTGPARLKGLLPIGTVVAHKTGTMG-GTTNDVGIVTLPDGGHLAIAVFVKA -STKDVPERERAIAELARTVYDFf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=A0A5F0TU92_STALE -----NSAIDKIEKKYDANVGMYALNTQNGEEL-SFNEDKRFAYASTLKAVSSAMLLEKVP ---SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNIANNKVIDELGGY -KEVKKRLVDLGDTMTYPSRKEPDLNLYTPKDKRDTTTPSAFGKTLNKLIIDGNLSKSNKD -FLMNLMLKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK -NNKDAKPNDKIVSEVAEEVLK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. 34-65-8 TaxID=1970335 RepID=A0A259JYF5_9SPHN -------RLRIIEAGANGVLGASFHDTGTGETV-SHNGFARFPHASSFKLSLAAMVLARDR -AGVIDADRLVRWTRADLMSYSPFTTERLEQGATLRELARATQTTSDNAAANALLRELGGP -EALTAFWRSLGDETSRLDRIEPELNLVPPGDLRDTTTPDAMARTVAALLYGPVLDAPRKA -ELRQWLIETRTGLDRVRAGLPPEWPAGDKTGTSLGSVYVDVGFVEPAGRAPITFAVYFRA -AQQHDPAALAAMAETGRVL---- ->[subseq from] class A beta-lactamase n=1 Tax=Maribellus sp. Y2-1-60 TaxID=2696285 RepID=UPI001431DA23 ---AISRKIEKISEGLVGRIGVAAQEIGSKEMI-TVNGDEQFVMASTYKVAIAVALLDRID -KGELKLTDLIDVEQETMVTGDGAIANHPGIKLSVANLIEPMITLSDNTATDACLKLAGGP -EAVTKMMRSIGITELRVDRYTSEILRFEQEDPRDQCSPYAMLQLLLAIDSGKALSEKSRE -FLLATMSRTRTGDGRLKGLLPKRTPVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVFTKS -STTSEANRDRAIAEVTRTLYDFy ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas sp. Leaf70 TaxID=1736233 RepID=A0A0Q4QWE8_9GAMM ---ALQAEAERLAAQLPGEVGAALVHLESGRAV-YVNGDRPLPMASTMKVPVAVHILKLVD -EGKLGLQQQVLLGPDDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP -EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGELLSPESTR -VLQQIMLDTRTGNARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVTTVFIK -SRASTEARDAAIAQLARAAHDYy ->[subseq from] class A beta-lactamase n=3 Tax=Acidomonas methanolica TaxID=437 RepID=UPI00104A3C6A ------ARLRAVEQTSGGRLGAFVLDIGSGRSF-GWRADERFCHCSTFKLSLAAMVLRESD -VGRLDLTETLSFSKADIVGYSPVVEENLAAGLSILALAKAVQITSDNAAANVLMRRLGGP -EAVTRFWREIGDDTSRLDGYEPSVNVIPPGTEANSTTPHAMADTVHRIVLGDVLSKGSRE -RLQAWMAATRSGQNRIRAGIPADWRGYDKTGTGMGNKTNDLAVLVPPGGSPLVVIGYFEN -PVAIRPADEAVLKRLGEVA---- ->[subseq from] class A beta-lactamase n=1 Tax=Micrococcus luteus TaxID=1270 RepID=UPI00069D22E7 ---HLDRALADLERQSSRKIAVTIGD-GEHQLY-SYRGTDPMPMCSLFKTILVGALLHDHA -YDEAFWNQKITFTKGEVVVNSPICSADADGVMTVDELADAALRWSDNTAGNLLLRLYGGP -AQLTAYAASLGMRQTRLDRWEPELNTAIPGDLRDTSTTNDMEKGFSDLLVGSALTQAGRA -RLRSWMLRNQTSGKRLRANLPATMELADKTGAGDYGVVNDAGVYWSGEE-TLSIAVMTRA -SFAGAMNDNTVVARIGQLAVQHy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000C31E8FC -----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00049AFA65 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQFMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAIYTNQ -DQKNAKPDDKIIAAAAKEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000623E4F7 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNKILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIFLAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas halotolerans TaxID=69670 RepID=UPI000F4AD346 -------DLSALEAANGGRIGLAAHDLASGLRL-ASRGEERFVYCSTFKMYLAAATFLRVQ -AGEEDLARPIPITRADMVSHAPVTEPAIGQSLTVEQLCKGTVEVSDNPAANLLLKANGGL -ETMQDFYRRLGDTSTRVDRFEPEMNRL--DGDKDTIIPLQSIANIKRLFIDDPLMVPHRD -KLLGWMFASPTGEGRIKAGLPAGWRTAHKTGTGGYGPTNDIGVLYPPTGEPVVLAIYYHA -TRSSAEQNDAVVAEATRLAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Larkinella sp. C7 TaxID=2576607 RepID=UPI0011112B7C --qRLNQELERIAKLAKGKVGLCAVHLESGKQV-SMNLQERFPMASTVKVAIAVELLTKIE -KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV -EPVRARLKALGIQGMSVDRTIVELIAKLEQDPRDTSTPEAMVNLLTQIYQAKALKPESRD -LLLAVMERCRGGLARIKGYLPPATVVAHKTGSLNSSATDDVGIITLPGDGHIVIAVFITA -SSQAAAEREQTIAHLSRTVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides litoris TaxID=1926648 RepID=UPI00111CE4A0 ---SLDPELTALEAERGTTIGLVARHRGTGREL-RHRPDARQPLCSTFKPLVAAALLVRGD -----CLDRVVRYDERDLVEYAPITGERR--AMTVGELADAAIRFSDNPAGNLLLRRLGGP -AALTAFLRRTGDRVTRLDRFETELNSAVPGDPRDTTTPRALAATYERLVCGDVLDARDRW -VLRGWLQSSTTSVDRFRSGLPAGWWCADKTGSGSYGVANDAGVVTAPDGTELVFAIQTRR -STTDATSDPTLMAALARLLV--- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. JM1 TaxID=1233950 RepID=A0A086AXZ1_9FLAO ----LEQKINSITEGKKATVGVSVLGFENNFKY-SKNGDQPLPTLSVFKFHIACVVLDLVD -KGKLSLDQKLFFKKEDMLEWSPIREKYPDANLPLSEVLDYTVALSDNNGCDVLLRLIGGT -QTVQKFMDSKGVKGFQIKHNEAEMHKSWKALYENYSTPNSAVQVLKKFYDGKLLSKKSTD -YLMQIMLRTKTGTNKIVEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAIAVFVND -SMETDAVNCKMVSDISKAVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Agaribacterium haliotis TaxID=2013869 RepID=UPI000BB5554B -----ATRIQALEQG-QARLGVCLLDTVTGEVT-GNRLDERFATCSTFKLAMVAACLREAD -HGRLNLDEILPYSEGDLLPWAPVTKKHLAEGLSIKTLAQAAQQWSDGVAANLLVKRLGGP -AAVTAKYRDMGDTVTRLDRYEPDLGLVLSADMRDTTSPLAYAQLVARILTADVLRDTTRK -QLLAWTQSTATGARRLRAGLPVEWQTGNKTGTGRTNKCNDVAITFPPGKNPIIIAAYFDS -GEKIEARHEAVLAEVGKIAAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A349Y3Q7_9GAMM ----VETEVARLATLVDGKVGVSAWRLDKGAQV-HLNPDEAFPMASTFKVAVAAVILTKVD -AGELALTTMVPVPKSFYVDSEVIADRFIHDGLSVHNLLEVMLTQSDNTATDVLVAQAGGQ -AAVTAWLRAQGIEGQRLDRNTRQLLSAFDKDPRDTSTPRAMSTLLTRLFTGKALSPASTE -VLVQIMERCRTCSARLRGSLPPGTKVADKSGTVA-GTVNDVGVVTLPDGSQFAISVFVKA -SNAPRSERERVIAEIARTVRDFy ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter marinus TaxID=538382 RepID=UPI001360EF51 ---------NILETAANGTLGVAVLDTGTGALW-GHNDYARFPQLSSFKLSLAALVLHLDE -RGDIDADERIGWGADELLDHAPFARERLGGGATLRELAEATQKLSDNTAANVLLRRLGGP -ARLTAFWRAIGDEASRLDRTEPDLNAVPPGEIRDTTTPAAAAQMLGRLLYGDALGAGARA -TLKAWMADTRTGQRRVRAGLPAEWPAGDKTGTSLGSVYVDVGFVEPPGAAPLTFATYFRA -ARQHDPAAEGVLAEVGRVIAR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A5N8AM03_9SPHN ----LAFPLSRLEQQAGGRLGFAIFDSSNGRSI-GINANDRFAFCSTFKMPLAAMTLEALD -KARLPADQLLPVTQADITTYAPITSKAIDIGMTARDLAAAAVIHSDNVAANILLAALGGP -AGFTHWLRAQGDAITRLDDIEPALNSVPAGSAENTTTPMAMARLFARLLGQSPLPPPSRE -QLGQWLRDSQTGLARLRAGLPADWKVGDKTGTASTGKVNDVAAIWHPDGHIITIAAFYEV -PLAMPADNDAVLAEAAKAACQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853315F -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC44_STAAU -----AKKLNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQIP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDS----------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Halieaceae bacterium GH4-78 TaxID=2547392 RepID=A0A4R5LTP0_9GAMM ----VAAAIEQFAAKLVGRIGFAAQEIGSDEVI-ALNGDETFPMASTYKVAIATAILDRVD -REELSLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLMGQAGGP -AAVTENLRRLGITDFRVDRLTGEIIGDFEADPRDHATPLAMLKLLLAIDSGTATSAESRD -FLIDVMSRTRTGAGRLKGLLPKGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEANRDRAIAEVARSLYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. Y8 TaxID=2591145 RepID=UPI0011C7C642 -----EVDLTTLERSTGYRVGVYARDTGSGDTV-TYRADERFGYASTLKALAAGEVLAGQP ---ASVLDRPLTVTAEDVADHAPVTADAAGTDLTIGALGGAAVSDSDNGALNVLLRHLGGP -AALQAALAARGDATTRVDAAEPELNRFTPGAPARTSTPRALAEGLATYALGDALGPAVRE -AYVGWLTASTTGLDAVRAGTPDGWVVGDKTGTAGFGSRNDVAVLWPPGRAPIVLAVLTDH -PDEAAEPDDAVLAAAARSVLAAy ->[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=J9HBE3_9STAP -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomycetes bacterium Pla144 TaxID=2528003 RepID=A0A5C6CZF7_9BACT --kDISQKIEKVTQGMVGRIGVAAQEIGGNEVI-AVNGDETFAMASTYKVAIATTVLDRVD -KGELSLDQLVEVQPDMYVTVTALAETFPHPGLSVANLIEVMITESDNTATDVCMELAGGA -AAVTKNLRRLGITDFRVDRTTREILMDFEADPRDHTTPLAMLKLLLAIDGGKAMSPESSK -FLLGVMSRTRTGAGRLKGLLPKGASVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVFTNS -SKTPVADRDRAIAEVGRTLYDFy ->[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=A0A656AYH1_VIBCL ------------------------------------------------------------- -----------------MVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3C1RJ36_9FLAO --sSLETQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYAE -KGKLSLDQKVTLNQSNLHEWSPLREKYPNGAVSLSEIIEYTVAKSDNNGCDILLKLLGGT -QVVQKFMNAKGVKNFQIKYNEEAMHKDWNAQYENYSTTNSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGTNKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN -STETAEVNCRMISDISKTIWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000E69C92C -------GFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINETDIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNKILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDNHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Uncharacterized protein n=1 Tax=Methylobacterium sp. SCN 67-24 TaxID=1660110 RepID=A0A1E4DK24_9RHIZ ---RLDAGIKSIEQTAKGRLGVALLDLRDRKSW-SHRGTEPFPMQSVFKLPLAVAVLQAVE -AGKLKLDQKITVTRNDLSLHSPLAKGFKGERYTLRDLLTRSTAESDNTAADLLLRLIGGP -QVLTAMLRDGGVPGISVDRYERVFQPASLKDRRDAASPDASAAFLEAFAKGNWLREPATT -LLDKIMLETKTGQQRIRAGLPQGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -SQADAKAREAAHAAVARLAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. AY-3R TaxID=2268576 RepID=A0A4Q2KJ72_9SPHN --------LRIIEAQGNGTLGVAVLDTGTGRVW-GHADYARFPHLSSFKLSLAALVLHLDE -TGAIDAGEHVTWSTDDLLAYAPFARERLEQGATLRELAEFTQKLSDNTAANLLLRRLGGP -ERLTAFWRALGDETSRLDRYEPELNLVPPGEIKDTTTPAAMARTLGKLLYGDALGEAARA -TLKLWMADTHTGTKRVRAGLPPEWPAGDKTGTSLGSVYVDVGYVEPPARAPLTFAAYFRA -ARAADAASEAVLAEVGRVIAR-- ->[subseq from] Beta-lactamase n=1 Tax=Providencia rettgeri TaxID=587 RepID=A0A2A5PZC8_PRORE ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWSPMMEEHPGDEVAVQQLLQYSVSHSDNVACDLLFELVGGP -AALDAYIRSIGVKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQAAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Mycolicibacterium aubagnense TaxID=319707 RepID=A0A5R8SCY4_9MYCO ------SSLANVEQRHGGRLGVFALDTGSGRTL-AWRADERFLMCSTFKGLLAGQILARVD -AGQEQLDRLVPYTEHDLIFTSPVTQVNVTHGLPVGTLLDAILEQSDNTAAVLLMRSAGGP -AGLTEFVRQLGDNVTRSDRYEPESNNT--NGVLDTTSPRAIVTTAQRLLLDDVLGPSSRA -ILEQGMVNCKPGLNRLRAALPDGWQGADRPGTSIEKETNDYLLARPPGAAPLLIAAYYDA -PGKPLAEREAVLREVGGLFV--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D4893 -----ASELKHIEQENDVTIGVYGMNTDNGKVY-KHNADERFAFASTYKAIASGILLNNMP ---NGKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNNELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASKQMDKDNQA -LLKQVMIENETGDSLIKAGVPKEYTVGDKSGQATYGTRNDLAFIYTDHRKPIILAVYTKQ -DQKNAKPDDKIIAAAAKEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas terrae TaxID=363631 RepID=UPI00141F17DC -------DLSALEQRFDGRMGFAFAT--EGKRG-AWRGDERFVYCSTFKMYLAAATLVRAQ -TGSEDLDRAIAITPADMLEHAPVTEKAIGKTLTITQLMKGTVEESDNPAANILIREMGGL -DAMRQFYRDIGDATTRVDRMEPEMNRW-D-GDKDTILPSQSVRNLEKLFLSEALKPESKR -LLLEWMVATPTGQGRMKAGAPSDWTVAHKTGSGGYGPVNDIGILYPVEGAPIVVAAYFHG -SASSNDQREAAIAEATRQ----- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCR7_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWSTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D9XBU6_9SPHN ---------SEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG -----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRLAQADRA -LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR -ADGSASDAEARLAEAARAIAD-- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter mirabilis TaxID=69666 RepID=A0A2D2ASR5_9CAUL ---ATERRLAELSRAQPGVLGVYVEDLATGWSA-GVEADAPRPMMSVFKAPMAAAVLAQVD -AGALSLEHKVTIRKEDLRGGPTIVADQFKGEFTVRELLGYAVSQSDNTATDALLPLIGGP -PAVTAYMRGKGIEGFRLDRDERALGAGFMADPRDTVTPRAAGAFLRQLAAGELVSPASTA -LLLDLMRKTTTGPRRIRVGMPTGSQLAHKTGGSGAIATNDIGLVTTPDGRRLAVAIFLSA -SPANDKERDALIAEAARIA---- ->[subseq from] Beta-lactamase n=2 Tax=Pedobacter nyackensis TaxID=475255 RepID=A0A1W2ENY8_9SPHI --nKLQQRMESIINGKKADVGVSVLYLENKRSV-SVNGDKHYPMQSVYKFHLALAVLDQVD -KGKFKLNEKIFVKKSDLLPWSPLRDKYPGGNVALTEIIKFTVSASDNNGCDILFRLLGGP -NKVHQYIAGLGIKDCEITATEEEMHNDDKVQFRNWTTPKSANALLEKFCNGKVLKKHTGD -FLMKVMEETTTGPNKIKGLLPPGTVVAHKTGFSGTAASNDVGIVTLRNGKKMIISVFVSM -SKESEKENEKIIAELAKAAWE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519HFU9_9CAUL -------DFSALETRNGGRLGFVALDMERGASV-GWRAAERFVYCSTFKMYLAAATFVRIQ -DGRETADRMIPITRADMVNHAPVTEPAIGSSLSVDRLMQAVVEVSDNPAANLLLKANGGI -EAMQNFYRSIGDDSTTVNRFEPEMNRL--DGDKDTIQPAQSVANLQRLFLDPALTTDSQA -RLLRWMFESPTGADRLKGGAPTGWQVAHKTGTGGYGPTNDIGLLYPPTGKPVIVAAYYHA -TSTSAAANDAVIADATRLALK-- ->[subseq from] Beta-lactamase n=2 Tax=Vibrio vulnificus TaxID=672 RepID=A0A3Q0L135_VIBVU --kDVSQKLETISQRLVGRIGVAAQEIGSGERI-TVNGDEMFVMASTYKVAIAVALLERID -KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP -EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSEKSSE -FLLDVMSRTRTGAGRLKGLLPKGTLVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVYSKS -STTSEADRDLAIAEITRTLYDFy ->[subseq from] Beta-lactamase n=1 Tax=Vibrio vulnificus (strain CMCP6) TaxID=216895 RepID=A0A3Q0KYQ0_VIBVU --kDVSQKLETISQRLVGRIGVAAQEIGSGERI-TVNGDEMFVMASTYKVAIAVALLERID -KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP -EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSEKSSE -FLLDVMSRTRTGAGRLKGLLPKGTLVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVYSKS -STTSEADRDLAIAEITRTLYDFy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBA9_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLYKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GJ90_9BACT ----LRQRLQRVASTTQGMLGIGVVDLSNGDTV-SVNGQGRFAMQSVYKFHLALAVLSEVD -RGKWTLEQKIKVTKKDLLPWSPLREKYPNGELPLREILEYTVAQSDNNGCDILFRLMGGT -KVVDKYIKSIGINEVNIVGTEEEMHADERVQFDNWSTPRSAAKLLEVFHQKKILSKNSWD -FLWNTLVGTTTGPRKLKGQLPQGTIVAHKTGYSGQGATNDIGIVQLPNGKRFAIAVFLNN -TSLPEAECDRAIAEAAKVAWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Myroides injenensis TaxID=1183151 RepID=UPI00028A13C2 ----LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLHGDRRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIEIRKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP -KTVEEYIKKSGINDIQITFNEEDMQSKWENMFQNWTTPKAASQTLKLFYDNNLLSKSSYD -FFWKTNKETTTGNNRIKGQLPEGTVVAHKTGSSGTAAVNNIGIVFLPNGEHFIISVFVSE -SKENFDTNEKIIADIAKATYDFy ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonadales bacterium BRH_c3 TaxID=1734408 RepID=A0A101V795_9SPHN ---RLAARLRIIEAAAGGTLGVALYESGSGRTL-AHRGDELFAHCSSFKLSLAAMLLHHDE -AGKIDAGEHVRWSAQELMSVSPFTKRRLEEGATLLELARATQTLGDNAAANILLKRLGGP -QALTEFWRTLGDPVSRLDRYEPDLNQVPPGEVRDTTSPLAMARTLEQILHGDVLNPANAA -LLMQWMSETRTGARRVRAGLPQDWQSGDKTGTSIDAIYVDIGFAHVPGGARYTFATYYRA -AREMDPAAEAVLAQVGGVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter farinalis TaxID=1260984 RepID=UPI001408209D ------ARLRALEQATGGRLGAFVLDTGSGHSF-GWRFDERFCHCSTFKLSLAAMALRASD -AGHLDLMEPLPFSKEDIIAYSPVVEKNLARGLPILKLAEAVQITSDNAAANVLMRRLGGP -AAVTRFWREIGDKTSRLDSYEPDVNVIPPGTEKNSTTPQAMAETVRKIVLGDVLSATSRE -QLRGWMAATQSGRNRIRAGIPDSWRGLDKTGTGMGNKTNDLAVLLPPDRSPLIVIGYFET -PVNIRPEDESVLRTLGEIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium soldanellicola TaxID=311333 RepID=A0A1H1FLZ5_9FLAO --pALDQQINSILKDKKATVGISVSGFENGFKY-SKNADKKLPMQSVFKFHIATAVLDFVD -KGKLSLNQKILLDQSNLLEWSPLRDKYPNGNVSLSEILDFTVAQSDNNGCDIMLKLLGGP -QTVQKFMDSKGVKNFQIKYNEEAMHKDWNAQYENYSTTASITDVLRKFFDGKLLSKKSTD -YLMKVMLGTKTGTNKLVEQLPKNTPVAHKTGASGTGAENDMGIITLPNGKHYAITVFVSN -STETDAVNCKIISDVSKVVWDHf ->[subseq from] Beta-lactamase n=7 Tax=Bacteria TaxID=2 RepID=P74842_SALTM ----LKEQIETIVTGKKATVGVAVWGPDDLEPL-LLNPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQSVTVNRAAVLQWSPMMKDHQGDEVAVQQLLQYSVSHSDNVACDLLFELVGGP -QALHAYIQSLGVKEAAVVANEAQMHADDQVQYQNWTSMKAAAQVLQKFEQKKQLSETSQA -LLWKWMVETTTGPQRLKGLLPAGTIVAHKTGTSGTAATNDAGVIMLPDGRPLLVAVFVKD -SAESERTNEAIIAQVAQAAYQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI0007047F31 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium gallinarum TaxID=1324352 RepID=UPI00143D0D34 --tTLEQKINAITKDKKATVGISVLGFENHFKY-SKNGEAKLPTLSVFKFHIACAVLNLVD -QGKLSLDQKIFIKKTDLPEWSPIREKYPDGNLSLNEVIDYTVALSDNNGCDLLLRLIGGT -QTVQQFMDSKGVKGFRIKHNEDDMHKNWKNQYGNYSTTNSAVQLLKKFYDGKILSRPSTD -YLMQIMLGTKTGTNKIVEQLPKGTPVAHKTGASGTVAENDMGIIMLPDGKHYAIAVFVNN -SYESDVINCKIISDVSKAVWDYf ->[subseq from] Beta-lactamase (Fragment) n=26 Tax=Bacteria TaxID=2 RepID=Q2FC64_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DN--------------------- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Riemerella anatipestifer TaxID=34085 RepID=UPI0012B30A30 ----LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLNGDKRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIEISKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP -KTVEEYIKKSGINDIQITYNEEQMQAKWENMFQNWTTPKAASQTLKLFYENKLLSQSSYD -FFWKTNKETTTGKNRIRGQLPEGTVVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE -SKEDFDTNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346QRV3_ECOLX -----------------------------------------FAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARRLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTT---------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=2 Tax=Pelomonas sp. BT06 TaxID=2135721 RepID=A0A397S288_9BURK ------PDFAALERRVQGRLGFFALDTGSGRTL-AHRADERFAIASTFKILLGARVAHGVE -VGRWSWDDKVPLHESQRVPHSPAFDRFLPRGATLAELVQGIVVESDNPCANVLLRHCESP -AGLTAWLREQGDQVTRLDRWETELNENAPRDPRDTSTPRAFAQTLQHLLLGPGLARTSQA -RLWADLQASRTGLKRLRAGVPARWRVIDKTGSGARGAVNDVALVFPPSRAPWVVVAFQSD -AKAAIDELNAVHADAVRLLVQAw ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000C34A732 ----SASEIKHIEDKNDVTIGVYGMNTENGKIY-KHNADERFAFASTYKAIASGILLNNTS ---QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI -KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT -LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ -SQKNAKPDDKIIAAAAEKAIE-- ->[subseq from] Beta-lactamase n=3 Tax=Pedobacter antarcticus TaxID=34086 RepID=A0A081PCI6_9SPHI -hnVLRQKAEELVKSKPAAIGFSIINLKTGDTL-SVNGEKHLPMQSVYKFHLALAVLKQVD -QNKFTLDQKILVKKKDLLPWSPLRDKYPGGNLPLSEILFYTVAQSDNNGCDILFRLLGGP -EIVNKYIHSLGIKDVEIRSTEEQMHADDQLQFKNWTTANAATQLLKRFYMGQLLKQPTND -FLMKIMAGTTTGTGKLKGKLPTGTEVAHKTGYSGQNATNDIGIITLPDGTHFAIAIFVSM -TALDEKASDQIIAELAKLSWDEf ->[subseq from] Beta-lactamase n=2 Tax=Chitinophaga flava TaxID=2259036 RepID=A0A365XUK5_9BACT ---PLTKKFEEIAAGSKGTVGVCATILETGETV-GLNSKMRFPMQSVYKFPIAMAVLDQVD -RGKLSMQQQIRVLPSDYIPHSPLRDEHPAGNVSITELLRYNVAESDGSACDVLLRVIGGV -KVADKYVHRLGIKDMRIALTEQVQVPNEPMQYQNWSTPEAMTALFKKFYTGHVLSDSSYH -YLLDILVNSAPGARRLKAQLPKGTVVAHKTGTSGTRATNDAGIITLPDGKHLIITVFIKD -SYADQETRERTIASISKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Arthrobacter sp. 9E14 TaxID=2058887 RepID=UPI000CE320B1 ---HLDRSIAALESANGVTIGIAAGR--RGQTAyTYRGGDTFPMCSLFKTLAVARLLRDHA -YDDEFWKRRILFREDQIVENSIICAADEDRDMSVEQLADAALRFSDNTAGNLLLELIGGP -MQIGAYARTLGAPSTRLDRWEPELNEALPGDLRDTSTPSDIHKLYEALLIGDALSTLGQA -CLRSWMLRNTTAGKRLGAAVSPGTELADKTGAGDYGVVNDAGVVWPDGRPPLTVAVMTKT -DDPDAVNNNEVVARVGQLIFA-- ->[subseq from] Uncharacterized protein n=1 Tax=Xanthomonadaceae bacterium SCN 69-123 TaxID=1660170 RepID=A0A1E4KXA8_9GAMM ---ALQAEAERLAAQLPGDVGAALVHLESGRAV-YLNADQPLPMASTMKVPVAVHILKLVD -EGKLGLQQQVLLGPEDIYPGGPM-DTHLSAGITIRDLLHMMITVSDNNATDILVRTGGGP -EAVQQRMRALGVDGLRVDRYIWELLAAWNADPRDTSSARAMAQLLQRTWKGEILSPASTG -VLQQIMLDTRTGSARLRGMLPSGTPVAHKTGTVGD-VINDVGVIELPNGRGHVVATVFIR -SRASSEARDAAIAQLARAAHDYy ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. YT40 TaxID=2547601 RepID=A0A4Y6VWW2_9SPHN ----LAAELRIIEAAGDGTLGVELYNTATGQSV-GLNSDRRFGMASTFKLSLAALLLQRDA -TGTVDADRRVTWSEAEVLSYAPFARERIATGASLRELARAAQVVSDNTAANILLRELGGP -AALTAFWRSIGDEVSRLDRIEPELNIVPPTEFRDTTTPAAMARNVAKLVYGDVLPEAERA -ELRGWMIATQTGLTRVRAGLPEGWVAGDKTGISGEGNYNDIGFAEGPKGGPITFACYFRA -RGETMKARDLALSRIGRII---- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000C32AD59 ----SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIASGILLNNTS ---QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI -KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT -LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ -SQKNAKPDDKIIAAAAEKAIE-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. CC-CTC003 TaxID=2565924 RepID=A0A4S4A4X9_9FLAO ----LSVQFQEIVKDKKATVGIAVYNFTTKDTV-TFNNTPDYPTLSVYKFHVALAVLHLVD -QGKLRLDQDIFVKKSELLEHSPLRENYPYGNIKLSELLSYMVALSDNNACDILFRLAGGT -KKVDRYIKNLKIKDTRITATEEEMHLKWENQYLNTTSPLAAVQLLQQFYQMKILSPTSYD -YLLNVMLGTKTGPDKLKGLLPKDILVAHKTGSSFKAAENDIGIVFLPGGQTYAIAVFVKN -SMEDDTTNNTIIAKVSKAVFDHy ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga eiseniae TaxID=634771 RepID=A0A1T4N6E5_9BACT ---NLSQQFETIAQAAKGTVGVSVLVLETGETA-GLNSKIRFPMQSVYKFPIAMAVLHQVD -KGKLKLEQPVRVLPSDYIPHSPLRDKYPAGNITVAELLRYNVAESDGSACDVLLRIIGGT -AVADRYIHDLGIKNIRIALTEQVQVPNEPMQYQNWSTPEAMTALFRKFYTGHVLSGSSYD -FLLDLLVNSGPGARRLKAQLPKGTVVAHKTGTSGTRATNDAGIITLPDGHHLIITVFVKD -AYADQETREKTIANTAKAAWDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium p7 TaxID=1560477 RepID=A0A0B5E3B9_9BACT ---------------ADSRVSYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15) TaxID=649349 RepID=E4RZ35_LEAB4 ---DFDQEVTALAKGKDLKVGVALIDLKTGEIK-QVNGDDPFPLQSVFKFHIAAKALEQVD -KGKWQLRDQISIEPGEIYTYSPIRDEIGTNLMRLDSLIYYMVSLSDNSACDILLRHLGGP -STVNEYIKEIGIKNTKIEVNELTMQSRWEEQYRNISTPLSVAETLKKFYLREYLSGDMHD -FLWALMENSPTGANRIRKGLPEGAVLAHKTGTSGSGATNDAGIIILPDGRAYVLVVFVSD -SKESDEVNEELIAKIAELI---- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=A0A1B1G4D2_9STAP -------GFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINKADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Uncharacterized protein n=1 Tax=Rhizobium taibaishanense TaxID=887144 RepID=A0A1Q9A9A0_9RHIZ ----SASKLRELEQKAHGRLGAYVLDPVRGTAF-GWRENEHFTHASSFKMSLAAMLLAKAD -AGQIDLDEILHWTKDDMLPVSPLTKANLDKGLSVRDLGRATLVTSDNTAANVLMRRFGGP -SQLTAFWRSIGDTVSRLDRYEPDLNDTPPGTDLDTTTPAAMAATTAAFVHGNVLSAGSRA -MLRAWMTDVKTGRDRIRSSFPVDWVSGDKTGTGIKHTYVDLAFGGPAGRGPLIVTAYFEP -IRPMDKNAVAVLAAVGHIVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium wanjuense TaxID=356305 RepID=A0A1I0P0G3_9FLAO --sALDQKISSIIKNKKATVGVSVLGFENGFIY-NKNGDKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKIVLDKSNLLEWSPLRDKYPNGGVPLSEIIEFTVAKSDNNGCDILLKLIGGT -QTVQKFIDSKGIKGFQIKYNEEEMHKDWNTQYQNYSTTASAVQTLKKFYDGKLLSKKSTD -YLMKIMISTSTGLNKIVEQLPKNTVVARKTGASGTGAENEIAIITLPNGKHYALAVFVSN -STETDAVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. T22 TaxID=2203219 RepID=A0A2Z3N1N4_9BACT ---SLYRQIAGIAEAAGGEVGVAARNLDGGPLL-QYRDSVRYPMHSVFKFPIAMAILHQVD -EGKLQLHQPIYIHQKWMVPWSPLRDSFPKGNKPLSELLALMVSQSDNIACDILIDLAGGE -AAINDYVRSLGITDINIAASEAKMASAWDVQFSNWAYPSAMVQLLDVLNKGAVLTKTSND -FLWKIMIETSTGPRRIKGLLPPDVVVAHKTGTGGTSATNDAGIIFMPGGQKLAITVFITN -SRADEATREGVIAKITKLIYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Rathayibacter sp. Leaf299 TaxID=1736328 RepID=A0A0Q5BVV0_9MICO ---AIDAALAADEAEYDARIGLVAVDTEDERTL-EHRADERFRSASSIKALAAGALLARTE ---PADLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP -AGLQEALRALGDDVTRVDRIEPELNRVSPE-GLDTGTARSLAADLRALLLGDALDPADRA -QLRDWMSGNATGDALVRAGAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER -RDPSLPYDDALVARAASVALE-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium luteum TaxID=421531 RepID=A0A085Z0A8_9FLAO --sALEQKINSITEGKKATVGISVLGFENNFKY-SKNGDQKLPMLSVFKFHIAAAALDLVD -KGKLSLDQKVFVSKTDLKEWSPFREKYPAGNVTLNEVIDYTVALSDNNLCDLLLKLIGGT -KKVQQFMDSKGVKDFQIRYNEQEMHENWKSLYENYTTPNSAAQVLKKFYDGKLLSKKSTD -YLMKIMTGTKTGTNKIIEQLPKNTPTAHKTGSSGKNAENDIGIITLPNGKHYAIAVFVSN -STEADAVNCKMVSDISKAVWDDf ->[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. FM1 TaxID=2484537 RepID=A0A3N2QFV5_9SPHN ---RLTAKLRLIEVGSGGTLGVMLLNTADGQAI-GHNSGERFAMCSTFKASLAALALDRAA -KGALDLDKVLHWRESDLQSYAPFAKERLATGATIRELARAAQVLSDNTAANLVLGAVGGP -SVLTQFWRSLGDDVSRLDNIEPLLNVVLPGRLENTTTPDAMARTLAKILFGGGVAPQAAQ -TLQQWMRETQTGTKKVRAGLPAEWVAGDKTGFSGQGVSADIGFAIPSDGAPIVFATYHRA -TTPPSPMADAAMSQVGGVI---- ->[subseq from] Beta-lactamase n=1 Tax=Providencia alcalifaciens TaxID=126385 RepID=Q8RK40_9GAMM ------------------------IKFPDDKTI-SINGNQRFPLDSTVKSIACANVLAKVD -AKKLSLSHSMIVTEKNIVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRAIGDTVTRSDRYEPELTVNPEGDLRDTTTPDAMSKSIKKILTGEVLSHSSKE -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSEVIRVLGSHILDEy ->[subseq from] Beta-lactamase class A n=1 Tax=Agromyces sp. OV429 TaxID=2135464 RepID=A0A3D9PEH0_9MICO ---RMTRDLHDLERATSVTIGVHAVGHGDRRAF-RYRGADVFPMCSLFKVLAAAALVRDRG -YDEGYWATPIPFTDADIVRDSLVLATLQPQQATPGQLADAALRYSDNTAGNLLLRELGGP -AAITSFAASLGANRTRLDRWEPELNEAVPGDVRDTTTPDDIALLYAALLLEDAAGVLASS -RLREWMLRNTTSGARMRAGLTAPYELADKTGGGEYGVVNDAGVLWRGGRDPLTLVILTRT -DRPDAVRNNEVIAEATRIVV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Siphonobacter aquaeclarae TaxID=563176 RepID=A0A1G9I621_9BACT ---SLRTKIEQITKGRKATVGVGIHAFRDGQTL-TINRNRHLPMQSVYKFHVALAVLKEVD -KGRFRLDQNMHVKKSDYVPHSPMSEAYPGGNLPLADIIRFMVADSDGSACDYLFRLLGGP -VRVNTVIHELGIQGVAIRNTEEMMQANWDVQYSNWTTPVAMLDLMKLFYQRKILSTRSYD -FLWKVMTETTTGQNRLKKRLPAGTVVAHKTGTSGTGAVNDVGFISLPDGSCIAVSVFVTN -STESMEANEQLIADIAKAAYDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Actinosynnema pretiosum TaxID=42197 RepID=A0A290Z441_9PSEU -------ELAALEERHGARLGVRVVDTGSGAAA-GHRADERFPVCSLVSAYAAGALLVAND -WADGFFQQVITYERAELIGNSPVTGARVDGGMTVAELCDAAIAHDDSTALNELLSLVGGP -EAITAFAFALGDEQTRLDRWEPDLNAAEPGDERDTSTPAALAAGYRNLVLGTALEARERA -ELRGWLEGGGT---VLRSVVPRGWAVGGKPGAAEYGTRCDAAIAWPPDRDPLVVVLMSTR -PERDARADGTLLADAARVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00049B0802 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAVAAEEAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A418IHK4_STAXY ----SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIVSGILLNNTS ---QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI -KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT -LLKQVMVENETGDSLIKAGVPKHYKVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ -GQKNAKPDDKIIAAAAEKAIE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium taibaishanense TaxID=887144 RepID=UPI000A071022 ----SASKLRELEQKAHGRLGAYVLDPVRGTAF-GWRENEHFTHASSFKMSLAAMLLAKAD -AGQIDLDEILHWTKDDMLPVSPLTKANLDKGLSVRDLGRATLVTSDNTAANVLMRRFGGP -SQLTAFWRSIGDTVSRLDRYEPDLNDTPPGTDLDTTTPAAMAATTAAFVHGNVLSAGSRA -MLRAWMTDVKTGRDRIRSSFPVDWVSGDKTGTGIKHTYVDLAFGGPAGRGPLIVTAYFEP -IRPMDKNAVAVLAAVGHIVAE-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A352FGR9_9BACT --qELQNQINQIAALAKGRVGVSAVVLETGETVaALNSQDHFPMQSIYKLPISMAVMKQVD -AGKIKLEQKVKVAKEDYVGHSPIRDKYRDGVLTVNELLRFALSESDGTASDVLMKLAGGP -GAIQAYLTELGIKDMIVLDTEQSFIQDHSLQYRNFATPGAAVALLRALYEHRGLSESSQA -LVLKFMTESTTGPKRLKGLLPAGTNVAHKTGTSGTAATNDIGIITLPGGAHAAIAVFISD -SPADEATREGTIAKIAKAVWD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBR6_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKISYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=Q5W3A6_9BACT --dSLEQRINSIISGKKASVGVAVAGIEDNFSL-SINGKKNFPMMSVYKLHIVLAVLNKVD -GGSLKLDEKIPLNKKDLHPWSPLRDKYPNGGIPLSEIIEYTITQSDNNGCDILIALAGGT -EAVKRYIISKGISDFDIRATEKECHESWNVQYSNWSTPVSAVALLKKFNDRKILSSVSTE -YLMNVMIHTSTGNKRIKGLIPPSADVAHKTGTSGTPGTNDIGIVTLPNGKHFAIAVFVSD -SRENNAANERIIAEISKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00034CE293 ----SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP ---NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIDEIGGI -EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0011A0F176 -----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKLQRLEPDLNDYDPTKIADTTTPKAAATNLNKLLTSKQMDKGNKT -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga cymbidii TaxID=1096750 RepID=A0A512RIS7_9BACT --dSLRNEIAAIAARSGGTVGVGIMNLHTRDTL-NFQNDPVYPMQSVFKFPIAMAILHQVD -EGKMKLEQKIYIDKKWMVPWSPLRDAFPDGNQTLAQLLEYMVSQSDNIACDLLIDLAGGE -AAINDYVHGLGVKQIAIVASEAKMASAWDVQFTNFCAPSAMVQLLDILHKGSALSKTSND -FLWDIMLKTSTGPKRLKGLLPVGTPVAHKTGTSGAAATNDAGIIVLPNGQKLAIVVYVMN -ARSDEATREATIAQIAKAAYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas terrae TaxID=405446 RepID=A0A0R0CBK8_9GAMM ---GLQTEAQRLAALLPGQLGAAIVHLESGRSV-YLDADRPFPMASTMKVPVAVHILKLVD -EGKLSLQQQVTLDADDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT -TAVNARMQALGITGMRVDRYIWELLAAWNEDPRDTSSALAMTTLLQKVWRGEVLQPASTR -LLQDIMLDTRTGTARLRGMLPKETPVAHKTGTVGD-VINDVGVITLPGGHGHAIVSVFVQ -SRASNEERDAAIAQLARAAHDYf ->[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. ZZJ9 TaxID=2315727 RepID=A0A368JTG3_9BACT --qRLNQELERIAKLAKGKVGLCAVHLESGKQI-SMNLQERFPMASTVKVAIAVELLTKIE -KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV -EPVRARLKALGIQGMSVDRTIVELIAKLEQDPRDTSTPEAMVNLLTQIYQAKALKPESRD -LLLAVMERCRGGLARIKGYLPPATVVAHKTGSLNSSATDDVGIITLPGDGHIVIAVFITA -SSQASAEREQTIAHLSRTVYDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. VAUSW3 TaxID=2010998 RepID=A0A219AEI5_9FLAO --qNLKKEILQITKGKNATVAVSVLDFENNKSV-HIRGNAKLPMLSVFKFHIALAVLNEVD -RGKLDLDQKIFIKKSDLLEWSPIRERFPEGNIPLRELIKYTVAESDNNGCDILLRLIGGT -ETVQKFISSKGIKNFTIKADEEQMHKSFEFMYLNVTTTNSANQLLQDFFNKKIVSKTSTD -FLMTTMLGTSTGRNKIVAQLPENIPVAHKTGSSGKNAENDIGIVTLPDGRHYAISIFVSD -SMESEATNTKMIADISKIVFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Rodentibacter sp. Ppn85 TaxID=1908525 RepID=A0A1V3JZS3_9PAST --tEWQQTITQQEQKLKADIGVALLSAEGKVLF-EYQGNRAFPLNSTHKAFVCGIALDLSE -DNLLSFNYQFPIQSSDIVSYSPITQHK--TAMSLTELCSAAVSYSDNTAANLIVKQIGGV -KVVSNYFKRQGLTQTRLDRTEPEMNRDNLKKGLDLTTPIEAVQLLHQFIFGDLLTQASKV -RLTQWMLDDQVANDLLRSTLPRDWKIADKTGAGSHGSRSIISVFWKPDGTAYLLSIYLTN -TQATMEQRNQAIAEIGKAIFDQ- ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A2T4QH63_STAXY -----ASELKHIEQENDVTIGVYGMNTDNGKVY-KHNADERFAFASTYKAIASGILLNNMP ---NGKLNKKIKINEQDMVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNNELKGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKAYTVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -DQKNAEPDDKIIAAAAKEAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus pseudoxylosus TaxID=2282419 RepID=A0A3M2QEZ1_9STAP -----ASELKHIEQENDVTIGVYGMNTDNGKVY-KHNADERFAFASTYKAIASGILLNNMP ---NGKLNKKIKINEQDMVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNNELKGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKAYTVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -DQKNAEPDDKIIAAAAKEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853E70D -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---DKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XDP4_9BACT ---DLQTQITSISQSIIADIGVAVIDVQSNDTL-SVNGNKHFPMQSVFKFHIALAALRQVD -EGKLSLDQKYHVTKDHYFNWSVLMREHPEANVTLRELITWCVMNSDNVACDLLFEILGGP -SHVDKFIKSLNVNDIAITANERKMHTDWYEQFSNWTTPSATARLLRLFYDGKILKDDSNK -FLWKLMADTPNAPNRLKGLLPEGTVVARKPGTGALGAANDVGILVLPNGKKIIVAAFVTN -TKEPLSTAEMAIAQISKAVYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter sp. L105 TaxID=1641871 RepID=UPI00131BEEC9 --eALQAKLQSVINAHQAIIGFSLMDLQNGDTL-TINGAKHLPMQSVFKFHLALAILNQVD -QGKLRLDQKILIRKSDLMPWSPLRDKYPNGEIPLSELLRVTVAESDNNGCDLLFRLIGGP -AKVNAYIHSLGVKEIAITATEHEMHHNEQAQFTNWTTARAATQLLKLFYSKHLLSASSQE -FLWNVMTGTTRISTKIKGQLPAGTPVAHKTGYSGTAASNDIGVVTLPNGKHFALAVFVSM -TKEDEKTIDATIAELTKTSWDY- ->[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. P6W TaxID=1609758 RepID=A0A2Z5E9W6_9SPHN ------DALRATEARAGGRLGAYILDPARGSGV-GWRENERFAHCSSFKMSLAAMILAGAE -RGEIDLGEVLRWSAQDLLPHSPVTSGAVDSGLSVKALAHATLVTSDNTAANVLLRRFGGP -AQLTRFWRSLGDKVSRLDRYEPELNRIPPGSEFDTTTPAAMAATMARLLLGDRLTPQGRG -TLKSWMTEVQTGSDRIRAGFPAGWTSGDKTGTGGQQTYVDLAFGGPANVPPLIVACYLET -SRDTKG----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1EC286 ----SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIASGILLNNTS ---QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI -KGFNKELKNLGDATSKPQRLEPELNNYDPAKIADTTTPKAAATTLNKLLSSSQMDKENQT -LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ -GQKNAKPDDKIIAAAAEKAIE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flectobacillus major TaxID=103 RepID=UPI00042713D4 ----LKQQIEQFLATKKAKVGVSVVGIESKEAF-AVNATGHYPLQSVFKFHLALAVLNQVD -KGILQLNQKIVVKKNDLLLWSPIREAYPAGDIPLSEILKYTVALSDNNGCDILLRLIGGP -KVLNTYLHKLGIKDVAITVNEEDMQKDWDTQFTNWSTPKAATDLLLMFYRHQILSQSSFD -FLWRTMVETTTGKKRIKGQLPEGTIVAHKTGTSGTAAVNDIGIVTLPNNQHFAISIFVAN -SKENTDTNEQIIAEITQLTWAYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ACAEC7 ---SVRQQIQHIVAGKKATVGIALMSDDGKDTA-SIYGNRHFPLQSVFKFHIALAMLSQID -QGKFSLDQPIKIQKKDLLPYSPIRDKYPNGTMNLSEMLAYTVSQSDNVGCDLLLKLLGGP -EAVERYIKQSGTNDISIKVNEETQQANWDLQFKNWTTPRAAVNVLQTFYVNKRLSTQSHD -FIWTVMKGTQTGQARLKGQLPKQTIVAHKTGSSGTAAVNDIGIVFLPNGRYYFISVFVKD -SRENEDTNEKLIADIGKATWDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WHU1_9BACT ----LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGSLRFPMASVYKLPIALRVLQRVD -RGELRLNAPVTLSTHDFRPHSPIVEFANNKPLPLERLLELMLGESDNSASDALLRLAGGP -AAVTNRMQALGIMGINVSRPEGQLILAYADDPRDTSTPDAMADLLVRIHRRDVLEPASME -RLLQITTATQTGPARLKGLLPIGTVVAHKTGTMG-GTTNDVGIVTLPDDGHLAIAVFVKA -STKDVPERERAIAEIARTVYDFf ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium mucoviscidosis TaxID=1945581 RepID=A0A202CD88_9FLAO --sSLDTQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAIAVLDYAD -KGKLSLDQKVTLNQSNLHEWSPLREKYPNGGVPLSEVIEYTVAKSDNNGCDILLKLLGGT -QVVQKFMNAKGVKNFQTKYNEEAMHKDWNAQYENYSTTNSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGTNKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN -STETAEVNCRMISDISKTVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas terrae TaxID=405446 RepID=UPI000A441A45 ---GLQTEAQRLAALLPGQLGAAIVHLESGRSV-YLDADRPFPMASTMKVPVAVHILKLVD -EGKLSLQQQVTLDADDVYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT -TAVNARMQALGITGMRVDRYIWELLAAWNEDPRDTSSALAMTTLLQKVWRGEVLQPASTR -LLQDIMLDTRTGTARLRGMLPKETPVAHKTGTVGD-VINDVGVITLPGGHGHAIVSVFVQ -SRASNEERDAAIAQLARAAHDYf ->[subseq from] Beta-lactamase n=2 Tax=Chitinophaga ginsengisegetis TaxID=393003 RepID=A0A1T5PCG6_9BACT --qTLRQQIAGIAGNISGKVGVYAEILETKDTV-SFNRDQHFPMQSVYKFPIAMAMLHQVD -QHKFRLDQPIHVTKDDLIGVSPVRDQHPEGNMPLGELIDYNIRASDGSACDVLLRLLGGT -AKANAYVHSLGVKQLAISTTEKVQVPSEMIQYKNWSTPMAMTQLLKIFYQEPVLSDSSKN -YLMHLMVTSRPGAKRLKGLLPAGTVVAHKTGTSWTRATNDVGIITLPNGHHLAITVFVSD -AKASEEEREGAIAKIAKAAYDHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=M9UY78_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKAYT-------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Riemerella anatipestifer TaxID=34085 RepID=UPI0007EDECC2 ----LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLHGDRRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIEIRKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP -KTVEEYIKKSGINDIQITFNEEDMQSKWENMFQNWTTPKAASQTLKLFYDNNLLSKSSYD -FFWKTNKETTTGNNRIKGQLPEGTVVAHKTGSSGTAAVNNIGIVFLPNGEHFIISVFVSE -SKENFDMNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. OV280 TaxID=2135471 RepID=A0A3E0ETF4_9SPHI --qDLKKAIETIANKHTAKIGFAVIDLQNGDAI-GFNGTVHYPMQSVYKFHLALAVLKQVD -EGKLKLDQQILVKAKDLLPWSPLRDKYPQGNIPLTEILGYTVSQSDNNGCDILFRLVGGP -AKVNQFINSIGLKDVAIVATEEEMHLDEKVQFKNWSTSFSAVQLLKMFYEKKILSKSSGD -FLWDIMVKTVSGPNKIKGLLPKGTIVAHKTGSSGTTASNDIGIVALPNGKHFAIAVFVSM -TKEEEKVTDQIIAECSKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio vulnificus TaxID=672 RepID=UPI001033EEC6 --kDVSQKLETISQRLVGRIGVAAQEIGSGERI-TVNGDEMFVMASTYKVAIAVALLERID -KGELKLSDLIDVPQETMVTGDGAIANHPGIKLSIANLIEPMITLSDNTATDICLKLAGGP -EAVTKVMRNIGITDLRVDRYTSEILRFEQEDLRDQSSPNAMLELLLAIDSGKVLSEKSSE -FLLDVMSRTRTGAGRLKGLLPKGTLVAHKTGTIG-GVANDVGFVTLPDGRRFAIVVYSKS -STTSEADRDLAIAEITQTLYDFy ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=2 Tax=Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007 TaxID=415956 RepID=A0A5S5DIG0_9SPHI ----LQPTIQKLLSKKKALVGVSIIHPEHRDTL-NIRGDEQFPMQSVFKFHIATAMLAKVD -EGRFSLHQVIPIKKEDLTPWSPLRDQYPDGVLPLSKIITYMLSQSDNVACDVLLKLLGGP -LAVETYIKSKGIQDIAIRINEETMQNNWDLQFQNWTTPKACTQTLQLFYYNQELSASCHK -FLWDVMKGTETGAKRLKGGLPAGTVVAHKTGFSGTEAVHDAGIIFLPSGQPIFITVFVSH -SQEDTANNEAIIADIAKLVYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sp. ZODW24 TaxID=2185142 RepID=UPI000DF82FC0 ----AAARVRSLEGESGGALGAAVLDTGSGEIF-GNRMDERFAHCSSFKLSLAALAMQRAA -NGGDALDTALPITADDITSYSPVTKARVGQTMTIADLAKTTLTKSDNAAANILLRQFGGP -EAMTAFWRSIGDDVSRLDRFETDLNFVPPGEVRDTTTPRAMAKTVQALLYGYALPGKMRQ -TLRSWMIETDTGLNRIRGGIPERWAAGDKTGTGFEGIYVDIAFAEPPSGAPLIITGYLRL -EERVEPNSAAVLAALGAIAA--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000E6860F7 -----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNSTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EVFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf299 TaxID=1736328 RepID=UPI0009E9D41C ---AIDAALAADEAEYDARIGLVAVDTEDERTL-EHRADERFRSASSIKALAAGALLARTE ---PADLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP -AGLQEALRALGDDVTRVDRIEPELNRVSPE-GLDTGTARSLAADLRALLLGDALDPADRA -QLRDWMSGNATGDALVRAGAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER -RDPSLPYDDALVARAASVALE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium P1 TaxID=1368078 RepID=A0A0B5ECS4_9BACT ---------------AGNRVDYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI0011C7836E -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGNSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAVAAEEAIK-- ->[subseq from] UPI0012E0C4A3 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0012E0C4A3 --dSLKSSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQGTYKFHLALAVLDKLD -KENISIDKKLFVKKSELLPWSPLRDKYPDGNLSISEILKATVSRSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -YLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000267D82B -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKVMEELGGI -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Beta-lactamase n=1 Tax=Francisella hispaniensis TaxID=622488 RepID=F4BK32_9GAMM ---QITNDIQNIEKKYGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TNSKLLNQKIKISKNQIVDYSPITKNHINQKMTIKQLCKASIQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTGSSRIAAEIPNEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIIAIFYTQ -SQKNAKPNSKILREVTKILLD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. JC507 TaxID=1978493 RepID=UPI0010A943E1 --qELRNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD -KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT -ETVQKFINQQGIKDFTIKVNEKEMAS-FEKCYINTTTPLATTELLEKFYKGKVLKKESTK -YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN -INEEMTDTEKIIADVTRAVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Microvirga TaxID=2617746 RepID=UPI0013766BBA ----------------SGRLGVGLVDLKDGSAW-SWRGDERFPMQSVYKLPIALAILTAAD -DGRLNLDDTIALGREDLSIWSPIAREFKGERYTVRQLAEHALQLSDNTASDALLRLAGGP -GSVTALLHRHGIAGMRVDRSEREMQPAYLADIRDTTTPKAAAHLLAKLARGELLSEPMTR -VFLGILAGTRTGGSRIKAGVPEGSAVAHKTGTAMTGAVNDVGIVTLPGGRQIVVAVFVAG -SDRPPAERERLIASVTRAAIE-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus lentus TaxID=42858 RepID=A0A4Y9KA80_STALE -----NSAIDKIEKKYDANVGMYALNTQNGEEL-SSNEDKRFAYASTLKAVSSAMLLEKVP ---SNKLDKKIHISKDDIVTYSPVLEKYVDKEITLKKLIEANMLYSDNTANNKIIDELGGY -KEVKKRLVDLGDTLTYPSRKEPDLNLYSPQDKRDTTTPLAFGKTLNKLIIDGNLSKSNKD -FLMNLMFKNKSGDTLIKDGAPSDFKVMDKSGQATYGSRNDVAFIYPKGQKPIILVIFTNK -NNKDAKPNDKIVSEVAEEVLK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI00057C0C8D ----SASEIKHIEDKNDVTIGVYGMNTENGKVY-KHNADERFAFASTYKAIASGILLNNTS ---QDKLNKKVKINEQDIVAYSPVTEKYIGKTMSLKSLVKASMLQSDNTANNKIIKEIGGI -KGFNKELKNLGDATSKPQRLEPELNNYDPTKIADTTTPKAAATTLNKLLSSSQMDKENQT -LLKQVMVENETGDSLIKAGVPKHYTVGDKSGQATYGTRNDLAFIYTDEHKPIILAIYTKQ -GQKNAKPDDKIIAAAAEKAIE-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A5R9B5K6_STAXY -----ASEIEHIEQENNVTIGVYGMNTDNSKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAAAAEEAIK-- ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3D4JXJ3_9FLAO --sSLETQINSIIKNKKATVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYAE -KGKLSLDQKVTLNQSNLHEWSPLREKYPNGAISLSEIIEYTVAKSDNNGCDILLKLLGGT -QVVQKFMNVKGVKNFQIKYNEEAMHKDWNAQYENYSTTNSAVDVLKKFYDGKLLSKKSTD -YLMKVMFSTSTGTNKLIEQLPKDTPVARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN -STETAEVNCRMISDISKTVWDYf ->[subseq from] CIA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium sp. ISE14 TaxID=475075 RepID=A0A316XIM9_9FLAO --sALDQKIKAVIKGKKATVGISVLDFDNNFEY-NKNGDKKLPLLSVFKFHLASAVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGT -QTVQNFMDSKGAKDLKIQYNEDDMHKDWKNQYGNYSTTNSAVDLLKKFYDGKLLSKKSTD -FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Ponticaulis koreensis TaxID=1123045 RepID=UPI0003B5B0A6 -----HTAIAYMESQNGGRFGVSAVNLATGQTI-THRGDERFAMCSSFKWLLAALVLQQVQ -TGEEDLSRMIEFSEADMVMHAPITEPALGEGLSVEALCRGTVQTSDNPAANLLLRTLDGP -EGFTQILRDNGEMTTRLDRWEPMLNENAPGDPQDTSTPNATVSLMGYYLFGGGLNAEYQT -LLKDWMIGATTGLARLRGGMDAPWIGGDKTGTSSNNQSNDVAFAYRPDADPILITSYLNV -ENPIGAETDELHATIGRQIM--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Roseovarius gaetbuli TaxID=1356575 RepID=A0A1X6ZRN5_9RHOB ----VAAAIERVATKLAGRIGFAAQEIGGDDVI-AFNGDETFAMASTYKVAIATAIMDRVD -RGELSLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA -AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRN -FLIDIMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SESSEADRDRAIAEVARSLYDYf ->[subseq from] Beta-lactamase class A n=2 Tax=Ruegeria marina TaxID=639004 RepID=A0A1G6R4G6_9RHOB ---SVGAAIERVATGLAGRIGFAAQEIGGDDVI-AFNGDETFAMASTYKVAIAAAIMDRVD -RGELSLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDILMGLAGGP -AAVTENLHRLGITDFRVDRTTGEIIGDFEADLRDHATPLAMLQLLLAIDSGTAMSAESRD -FLIDVMSRTRTGDARLKGLLPRGTPVVHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F6KHM3_ECOLX ------------------------------------------------------------- --EPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTS--- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Cyanobacteria bacterium 13_1_20CM_4_61_6 TaxID=1805100 RepID=A0A1Q8BMQ5_9CYAN ---ELQKRFEVIAKAANGKVGVAVELLETKESI-VLNGQERFPMQSVYKLPIGMAVLQRVD -EGTLKLEQLIQVTPNDFVAHSPIRDAHPLGALSVSNLLQQMVSESDGTACDVLLRLLGGP -ASVGGSLRKLGLTNVVVATTEKEMGQDELVQYRNWAAPEGLTRLLRWLHEGRGLSVPSRE -LLLRFLTETSTGPRRIKGLLPVGTPVAHKTGSSGARATNDAGIVTLPDGRHVAIAVFVSD -SAADEATRDAVIAKISRAAWDYw ->[subseq from] Beta-lactamase n=2 Tax=Francisella novicida TaxID=264 RepID=A0Q6M5_FRATN ---QITNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILNKKHRL -MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000397D5A4 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQLDDKVIADAAEEAI--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter alkalitolerans TaxID=492736 RepID=UPI0003FB1EEE ---DFKSQIESITKQIDGIAGVAIKDLGGNETL-ILNADHKFPMLSSFKFPIAMAVLDQVD -KGKLALDQKYHLTKEDVQLYSPLRDKYPDGNLTIGDLLASMVSLSDNIACDILFKLAGGT -KPVQDYVHSLGVKDIAIVANEEEMGQDWNVQYTNWCKPGAMLQLLNILYKGKNLSKSSHD -FLSKIMIDGPTGMNRIKGQLPKDAVVAHKTGTSGNGAVNDVGVVKMPNGKSFAIVLFMSN -STAELKAIESVMAQVSKAAYDHy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCQ5_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDILD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] class A beta-lactamase n=1 Tax=Algoriphagus formosus TaxID=2007308 RepID=UPI000C2858DB --eALSKKIENLTEKLAGRIGVAAQEIGSKETI-TINGDEQFVMASTYKVAIAAAVLDRVD -RGELRLDQMVDVTLDMMMIGDAALNRFVHPGLSIANLIEVMITESDNTATDISMGLAGGP -AAVTNYLRRIGISDFRVDRSTGEIIGDFEADPRDQATPFAMLQLLLAIDGGKATSSESRD -FLINVMSRTRTGSGRLKGLLPKGTPVANKTGTIG-GVANDVGYITLPDGRRFAIVVFTKS -STTSEADRDRAIAEVTRTLYDFy ->[subseq from] Beta-lactamase n=1 Tax=Francisella uliginis TaxID=573570 RepID=A0A1L4BS25_9GAMM ----ISNEIHKIEKQHGGKVGVYTINRNNWHNF-THSETFYFPICSVYKFLVVGAILKESM -TDSNLLDEKVRISKNQIIGYSPITKKYVGKEITVKELCKASI-LSDNTATNLLIYKLGGL -KKLGAFILSLKDHATKITALEPKINDVNLKNNLNKTTPKIIARDLNKIAFHDVLDKKHRI -LFKKWLKENNTGSNRIAAELPKGWKIGDKTGTCDYGSTNDVAIVWPNDSRAIVISILYTQ -PLKNAKPNDKVIQEVAKILFDNf ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. T16E-39 TaxID=2015076 RepID=A0A220S929_9FLAO ---SLEQKINSIVNGKNATVGVSVLSIENDFNY-NKNGEKKLPMQSVFKFHISSAVLDLVD -KGKLSLDQKVLIKKSDLLDWSPMREKYPAGNLPLSEIIDFTVAQSDNNGCDILLRLIGGT -STVQKFMNSKGVKNFQIKFNEEEMHKGWNVQYENFSTTNSIVDVLKKFYQGKLLSKKSTA -YLMKVMLGTKTGANKLVEQLPKNTPVAHKTGSSGTGAENDMGIVTLPNGKHYAIAVFVSN -STETEAVNCKIISDLSKVVWDDf ->[subseq from] Beta-lactamase n=1 Tax=Providencia sp. TaxID=589 RepID=A0A356D3P4_PROSP -----------IYEKEGWKVGLSILY-SDNSSI-SINGNQRFPLDSTVKSIACANVLAKVD -AQKISLNHSMIVTEENIVTYSPVAKNYINKPFTLEKACKAANEYSDNTAANFAILSGGGP -EGLTAFMRSIGDTVTRSDRYEPELTTNPVDDLRDTTTPNAMSLSIKNILTGEVLSNASKD -QLKEWMMNNKVADNMLRASLPKGWKIADRSGASDYGIRGITSMVWSNDHEPVFISIYVRK -GDTSLEERSEVIRILGSHIFNEy ->[subseq from] Class A beta-lactamase n=1 Tax=Larkinella sp. MA1 TaxID=2607654 RepID=A0A5N1J9J3_9BACT --qRLNQELDRIAKLAKGKVGLCAVHLESGKQV-SMNLQERFPMASTVKVAIAVELLTKIE -KGDLSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV -EPVRARLKALGIQGMSVDRTIVELIAKLEADPRDTSTPEAMVNLLTQIYQAKALKPESRD -LLLAVMERCRGGLARIKGYLPPATVVAHKTGSLNSSATDDVGIITLPGDGHIVIAVFITA -SSQAAAEREQTIAHLSRTVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6E4L5_9BACT ---TLEAEIRRITNAAGGEVGVAAWRLDSGPRM-LLNADEAFPMASTFKVAVAGALLGKVD -AGTLSLETVLPVDKSRYVESEVIADTLIHSGLSIHNLLELMLTRSDNTATDVLTSAAGGA -TAVTAWVRAQGITGLRVDRDTAGILRAFDKDPRDSSTPNAMAELLSKIFTGHALSSASTK -EIIETMERCHTGNDRLRARLPATTTVADKTGTLG-GSVNDVGVITLPNGGQVVCAVFIKK -SDLPFADREKVIADIARAVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas mali TaxID=40682 RepID=UPI000A020036 ------ADLRALERRAKGRLGAYVLDPVRGVRF-GWRENERFAHCSSFKMSLAAMILAKAD -RREIDPAEVLHWTKADMLGVSPVTEAKIDAGLAVEDLARATLVTSDNTAANVLLRRFGGP -VQLTRFWRSIGDDVSRLDRYEPELNQTPPGTELDTTTPAAMAATTAALIHGKTLSRASRA -KLKAWMREVRTGRDRIRSGFPTGWDSGDKTGTGIKHTYVDLAFGGPAARTPLIVTAYFEP -ARPMDPVATAALAEVGRIAA--- ->[subseq from] Beta-lactamase n=1 Tax=Francisella hispaniensis FSC454 TaxID=1088883 RepID=A0A153JBG9_9GAMM ---QITNDIQNIEKKYGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TNSKLLNQKIKISKNQIVDYSPITKNHINQKMTIKQLCKASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTGSSRIAAEIPNEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIIAIFYTQ -SQKNAKPNSKILREVTKILLD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A076Q258_ECOLX ------------------------------------------------------------- ----QLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLILVTY--- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2D6NKY0_9SPHN --qDLAARISEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG -----LREKRLHFGAXDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAAXLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNEXAPGDPXDTTTPTAHADLVGTLLWGDRLXXADRA -LLQEWLXXTTTGMNRLRAGLPXEWRAGDKTGTCGQGEVNDIAMFETPDGARYILAAYLDR -ADGSASDAEARLAEAARAIAD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Polaromonas TaxID=2638319 RepID=A0A258TKB8_9BURK ---RFQKEIRQIETDSGGRLGVSVLDTHSGLAY-AYRGDERFPMCSTFKFLAAALVLSRVD -QGQEQLSRRIAVQASDIVPYAPATQPRVGGVMTVAELCDAAVTLSDNAAGNLLLKSFGGP -PGLTAYARSLGDEFTRLDRIEPDLNEATPGDPRDTTTPDAMLKTMQKIVIGPALSPASRE -QITRWLTDNKTGDK---------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A521NGC4_9CAUL --------LSGLERANGGRLGFVAHDGGSGRRL-AWRGDERFVYCSTFKMYLAAATFLRVQ -AGQERLDRQIPVAGADMVNHAPVTGPAVGGALSVETLMKGAVEVSDNPAANLLLRALGGL -EPMRAFYRSLGDDSTTVDRFEPGMNRL--DGEKDTIVPLRSVANLKRLLIDTPLSEDHKA -RLLRWMTDTPTGQGRIKAGLPVGWTVAHKTGTGGYGPTNDIGVLYPPAGAPVIVAAYYHA -AAGPADRHDAVIAEATRLAL--- ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XER2_9BACT --aKLKSEIETISKDAKGIVGVGVMDLKTRETL-LMNQEHKFPMQSTFKFPLAIAVLDLVD -KGKYKINQKIHVKSAGLDPHSPMRDKRPNQDITIGELLSYSVSESDNNACDILFELAGGT -KKVNEYIHSLGVKDIAIVATEKEMKAGWDVQYTNYARPSAYLQLLQIAYERRKLSKASHD -YLWKMMVEGPTGLKRIKGLLPKGTEVAHKTGTSGTNATNDAGIIRLPNGKDIAVVVFVSD -AAANMDTRELVIARIAKAVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000D1CFF96 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKVMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus sp. KY49P TaxID=2664181 RepID=UPI0012998B8E ----SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGILLNNVP ---NSKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIDEIGGL -EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKKYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] Beta-lactamase (Fragment) n=6 Tax=Bacteria TaxID=2 RepID=A0A411NN22_ECOLX ------------------------------------------------------------- ----------------DLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDV------------ ->[subseq from] Beta-lactamase n=1 Tax=Pelomonas sp. TaxID=1909303 RepID=A0A5C7VJN7_9BURK ---DLAPALAALEARAGGRLGFAALDTGSGRLL-GHRLDQRFGMCSTFKLPLAALTLRAVE -QHEL-QDDWVALGEISPRDFAPATRAQLPAGMKLLALAEAVQTTSDNIAANLLLARLGGP -AGFTQRLRALGDPVTRLDRVEPLMNRVLPGDERDTTTPAAMAQTVAAIFTGEWLQPAGRA -TLRRWAEATRTGVRRLRAGLPADWPAGDKTGTGLAARTNDVAIMWPPGRAPWVMAAYFEG -PGSDPAADEAVLAEAARLAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158B2FA ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WV98_9BACT ----LERAIKRLAESSGGIVGVSAIHIESGRRV-SMNGGTRFPMASVYKLPIALQLLNKVD -RGELRLQDSITLSAHDFRPHSPIVEFANNKPLTLERLFELMLGESDNSASDALLRLAGGP -AAVTNRMQALGITGINVSRPEGELILAYADDPRDTSTPDAMADLLVRVHRRDVLEPASME -RLLQIMTATQTGPARLKGLLPTGTIVAHKTGTMG-GTTADVGIVTLPDGGHMAIAVFVKA -STKEVPERERVIAEIARTIYDY- ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2U8T2R2_ECOLX ----------------------ALINTADNSQI-LYRADERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPITEKHVNGTMTLAELSAAALQYTDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASW------------------------------------ ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Fimbriimonas ginsengisoli Gsoil 348 TaxID=661478 RepID=A0A068NK12_9BACT ------GRVQALEAGLHGSIGVAVTDLRTGESW-AYHGDSRFPMQSVFKLPLGIAVLDAVD -RREHSLDTRIMVGWQHLSVMSVINDRFSGHAYSVAELLELAVGVSDNTAADLLLSMMGGP -QKVTARLKRMGINGIRVDRFERQLQVKYLADPRDTATPNGMVDLLAGLQRGRFLSPASRE -RLLRIMTASTTGPNRLKAGLPKGSTLAHKTGTGRCGAINDVGIATLPGGRKLAIAVFLSG -TSGTKTTRERIIANVARAVTD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chitinophaga sp. SYP-B3965 TaxID=2663120 RepID=UPI0012998278 ---RLRLQIAQIAATIDGQVGVSIRNLDTRDTV-TFNDTTNYAMHSVFKFPIAMALLHQVD -QGRLQLEQKIYIDKKWMVPHSPLRDSFPAGNVTLSHLLSLMVSQSDNIACDVLIDLAGGE -GAIDEYIHSLGVKDIAIAASEAKMASSWDVQFTNWSTPTAIVDLLEILNKGTALSKTTNA -FLWKIMTETSTGPHRIKGLLPANVVVAHKTGTSGYAATNDAGIIFLPNGQKLAIVVFVSM -SKADEATREGVIAKVAKAAYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Cytophagaceae bacterium TaxID=2026729 RepID=A0A4Q5R1H2_9BACT ----LQTELERVVAGFAGTVGVVVRGVEGGDSA-QLQAQAHLPMQSVYKFPLALAVLHAVD -EGRLQLDQKIWLRPADLLPWSPLRERYPQGNVSLREVLRYTVAESDNNGCDMLFRLLGGP -AAVQAYMHRLGVADLRIAATEEEMHRQEDVQFKNWATPFAMSELLVNFSRGHYLSAASHA -CLWQLLTTGPTGLQRLRAGVPTGTEVAHKTGTSGTNATNDAGLLTLPNGRHVAVVVFITN -STASEADRESLIAAVSRTAWQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium saccharophilum TaxID=29534 RepID=A0A1M6ZPK6_9FLAO --sDLRQQLNQIIATKNATVGISIKSIEDKDTI-SINGNLKAPMMSVFKFHIALTVLSQVD -EGKLSLNQKIFIKKKELHEWSPMREEYPNGNLTLDQVLRYTVSHSDNNGCDILIDLVGGT -KVVQKFIDKQGIKDFVIKVNEKQMES-WKNLYVNTTTPLATTELLEKFYKGEVLKESTTQ -YLYQIMVETSRGLTWMKAGLPAGTELAHRTGTSGTNAMNDIGIVKLPNGKHFILSVYLKE -ITEKQEDTEKVIADIARATWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI00085315A9 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIAYAAEEAI--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A248XBE9_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMSKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHIA------------------ ------------------------ ->[subseq from] Class A beta-lactamase n=2 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TSY2_9GAMM ---ALQREAERLAGQLRGSVGAAAIHVESGRSV-FVDGDRAFPMASTMKLPVAVHILKQVD -EGTLSLTQQVLLAPGDVYPMGGPMDLHLTPGITVRDLLHMMITVSDNNATDLLLRLGGGT -AAVDARMRALGIDGIRVDRYIWELLAAYNADPRDTATARAMATLLARLWRGELLSADSTQ -LLQAIMQATRTGGDRLRGALPPHTPVAHKTGTVGD-MVNDVGVITLPDGRGHVVVVAFVQ -SDAPAATRAGTIAQLARAAHDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0K2DRT4_KLEPN ------------------------------------------AMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGEALGDSQRA -QLVTRMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Francisella tularensis subsp. novicida PA10-7858 TaxID=1386968 RepID=A0A1I9Y9W4_FRANO ---QITNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -IFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase n=2 Tax=Actinosynnema TaxID=40566 RepID=C6WI80_ACTMD -------ELAELEERHGARLGVRVVDTGSGAAV-GHRADERFPVCSLISAYAAGALLVAND -WADGFFQQVITYERAELIGNSPVTGSRVDGGMTVAELCDAAIAHDDSTALNELLSLVGGP -EAITAFAFALGDEQTRLDRWEPDLNAAEPGDERDTSTPGALAAGYRNLVLGTALEARERA -ELRGWLEGGGT---VLRSVVPRGWVVGGKPGAAEYGTRCDAAIAWPPDRDPLVVVLMSTR -PERDARADGTLLGDAARVAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=uncultured bacterium TaxID=77133 RepID=E4WMD6_9BACT -------ELDSVPQVSSGRLGVAILDFQTSKTY-HINGKDRFPMQSVFKAMSAVVVMREVD -EGKLTLDQEIPVGPDDISVWSPIAEEFKGTTYTVRELLEKSVGMSDNTAADVLMELTGGP -QAVTQLLKDAGIEGVRVDRYERQFQAVAGKDERDTATPLGAVDFLVKLQEGKLLSAESTR -VLLQIMTDVKTGAGRLKAGLPEGSKLAHKTGTGGNTATNDIGIATLPDGRKFAVAVFLTG -SKESEEKRDAIHADVVRQFVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 7 TaxID=2035214 RepID=A0A497V3G5_9FLAO --kDLRNKINHIISTKKAEVGISLKGIENKDTL-SINGKKETPMMSVFKFHIALAVLNRVD -QGKLKLNQKFFIKKEDLLPWSPIREDYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT -ETVQKFINQQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK -YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN -INEEMADTEKIIADITRTVWDYy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A418IL74_STAXY ----SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP ---NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIHEIGGI -EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -AQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium oleae TaxID=491207 RepID=A0A1I4VLE3_9FLAO ----LEQKINSITEGKKATVGVSVLGFENNFKY-SKNGDQPLPTLSVFKFHIACTVLDLVD -QGKLSLDQKLFFKKEDMLEWSPIREKYPDANLPLSEVLDYTVALSDNNGCDVLLRLIGGP -QTVQKFMDSKGVKGFQIKHNEAEMHKSWKALYENYSTPNSSVQVLKKFYDGKLLSKKSTG -YLMQIMIGTKTGTNKIIEQLPKNTPVAHKTGSSGKNAENDMGIITLPNGKHYAITVFVND -SMETDAVNCKMVSDISKAVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DAF683 --------------AARGNVGIGVLDLKTGKSW-FRNGKQRFPMQSVYKVPIAIAVLKRVD -EGKLALNQSVTVTRQEFAPWSPMTQEFKGNSFTVQNLLERSVGISDNTAADVLVRLVGGT -EQVNAILGKLKIRDVRVDRLERQLQSKYLADPRDTATPEGIVDLLVKLQSNQLLSQKSTA -LLLKIMTDSPTGAKRLKAGLPHNWSIAHKTGTGPGTATNDVGIVSSPNGKRVAIAVFVAG -SKAPIEAREKVMSDVASVVVK-- ->[subseq from] Beta-lactamase n=1 Tax=Chthoniobacterales bacterium TaxID=2201154 RepID=A0A2W5ZLY3_9BACT ----AQSEIERIATTAAGQVGVAAWRLDTGPRL-LFNADQSFPMASTFKVAVAGALLAKID -AGKLKLDQMLTVDPAQYIESEMIATTHPGVSLSVHNLLELLLTYSDNTAADVLTAAAGGP -EAVTAWVRSQDVNGLRVDRDTGGILRAFDNDPRDTSTPTAMAELLTKLFAGHALSPAGTK -TLVETMERCHTGDNRLRARLPAPTTVADKTGTIG-GSVNDVGLITLPNGGQVVIAVFIKK -SDLPFAAREKVIADIARATYDFf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia pneumoniae TaxID=228601 RepID=UPI000594C8FC ------PSFTEMETNHAARLGVYAIDTASGRTV-GHRDGERFPMASTFKGLACGALLRDHP -LSTGYFDQVIHYSRADLVANSPVTEKHVDTGMTVAELCDATITVSDNTAGNQVLKLLGGP -AGFTAFLRSIGDNTSRLDRWETELNTAIPGDERDTTTPAALAADYRALVLGDVLGEPERE -RLKSWLIANTTGDKRIRAG----------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. CGR2 TaxID=1805820 RepID=A0A3B0B8X3_9MICO -haDTEQELVALEQEYNATIGVVAVNTGTGESV-SYGENRRFGFASTIKAFAAAEFLRTVQ ---GPDRDELVHWTADEADANAPVTSQHVEEGLTYAQLAEAAVRFSDNAALNLVFDRIGGP -QALDDALTDLGDTTTEVVNNEPTLNTIEPDSTEDTTTAAAFTASFEAYLDGSTLTAADTA -LLLDWMSDNRTGDPLIRAGAPAGWVVADKSGGAGP-IRNDIAMITPPGEAPILLTVLTSR -NDPDAAFDNTLVARTASTML--- ->[subseq from] class A beta-lactamase n=1 Tax=Acetobacter farinalis TaxID=1260984 RepID=UPI00140DCCC0 --------LDAIENRYGGRLGVFAQDTASGRTL-MHRPDERFTMCSTFKGLLAAQVLWKIE -RGQEQFSRLIHYTARDLKDACPVTAANVQRGLTVEALCQAMVEMSDNLAAILLMRSIGGP -SSLTAFVRSLGDTVTRSDRYEPFSNTY--DGLLDTTTPRAIAKTAGTILLGSTLQQDTRD -LLTRWMINTKPGLQRLRASFPGDWVSADRPGTSGPDETNDYAVVWPPGRKAILMAAYYHA -PHISMDGREAVLRHVGSVI---- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D71A7 ----SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP ---NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIHEIGGI -EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -AQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=A0A2T4QBZ7_9STAP -----ANEFDQLEKENSTTVGVYGINTESGEEI-NHHSDERFGYASTFKAIASGVLLNNYT ---EKELNKKIQIQQKDIVAYSPVTEKYVGKQMSLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKADLQQLGDHVSDPQRLEPKLNDYEPTSTADTTTPRAAAHTLNELLTSHQMNTKNLK -LLKRVMIENETGDQLIKAGVPKHYLVGDKSGQGTYATRNDIAFIYPKDDKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=A0A4Y9KQC1_STASA ----SASELKHIEQENDVTIGVYGMNTDNGKVY-KHNSDERFAFASTYKAIASGVLLNNVP ---NGKLNKKIKINERDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIHEIGGI -EGFNNELQGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLASNQMDKDNQA -LLKQVMIENETGDSLIKAGVPKQYIVGDKSGQGAYGTRNDLAFIYTDHRKPIILAVYTKQ -AQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter mangrovi TaxID=1982042 RepID=UPI000BA22C79 ----IDAKLHLIEVANGGALGAALLDPLSGDVI-GNRADERFALCSTFKASLVALVLDLGI -AGKLDLGEVVYWTQADLLSYAPFAKQRLANGATITELAGAAQILSDNTAANLLLQRVGGP -EGLTAFWRSLGDEVSRLDDIEGALNHVLPGSERNTTTPRAMATTLAKILYSGAIAREASD -QLKAWMRETQTGAKKVRAGLPQGWDAGDKTGNSGYGVSADIGFAVPPNGAPIIFAAYHRA -AAAPSANADAALAQVGEAI---- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6E5T9_9BACT ---TLEAEIRRIANAAGGEVGVAAWRLDSGPRM-LLNADEAFPMASTFKVAVAGALLGKVD -AGTLSLGTVLPVDKSRYVESEVIADAFIHSGLSIHNLLEVMLSRSDNTATDVLTSAAGGP -GAVTAWVRAQGITGLRVDRDTAGIVRAFDKDPRDSSTPNAMAELLTKIFTGHALSSASTK -EIIGTMERCHTGNDRLRARLPSTTTVADKTGTLG-GSVNDVGVITLPNGGQIVCAVFIKK -SDLPFADREKVIADIARAVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Cytophagaceae bacterium BCCC1 TaxID=2015573 RepID=A0A257IYG5_9BACT ---DLNKQFSEIIGDKKVKVGICVYDFKTKNFY-SINLKEHFPMQSVFKFHIALAVLDLVD -KGKLSLSQKVYISKERMEAYSPLRDKYPNGNLTIAEILKPTVSESDNVGCEVLLDLIGGP -KTVDDYLKKIGMKDVQVKHNETIMQASWEPQFENYSSPNSAVELLKALHNGKILSPKSRA -YVQKMLLETSTGPNRLKGLLPKGTVVAHKTGTSGTNAVNDIGIITLPNGNQFAIAVFVSN -SKEKIETNEKIIAEIAKATYDY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WQ24_9BACT --dELQKQIERIAASAKGRVGVAAEVLETGESI-SLNPQDHFPMQSVYKLPIGMAVLAHVD -TQKLSLDQRVRVEKSDYVRHSPIRDKNPKGVLTFKELLRFAVSESDGTASDVLLKLA-GV -EAVAKYLNELGISEIVVANSEKEIGKDWETQYRNWASPQGALQLLRGLHEKRGLTEQSQQ -LLLKLMTETPTGPKRLKGLLPQTVVVAHKTGTSGSAATNDIGLITLPSGRHLAIAVFVSD -SPADLPTRERVIAEIAKAIYDAy ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter sp. OK701 TaxID=2135718 RepID=A0A4R7EPX5_9SPHI ----FRNKLNEIVKAHKATIGYSLLDLQNGDTI-TVNGAKHLPMQSVYKFHLALTVLHQVD -QGKLQLDQKILVRKQDLLPWSPLRDKYPAGNIPLSELLSFTVSQSDNNGCDILFRLMGGP -AKVQQYIHSLGVSEVAIAATEEQMHRDDQMQFTNWSTARSATQLLGLFYAKPILSKSSAD -FLWKVMSETTTGPNKIKGLLPPATEVAHKTGYSGTAATNDIGIVTLPNGKHFAIAVFVSM -TTEDEKTTDRIIAELSKASWDE- ->[subseq from] Class A beta-lactamase n=1 Tax=Hymenobacter sp. MA3 TaxID=2607656 RepID=A0A5N1IT66_9BACT ---TLAQQFAALAKPAGGRVGAAATLVETGETV-TLAGAEHFPMQSVFKLPIAMLVIHQVE -QGKLRWTQRVRLAPADMRKHSPLREQHPQGTLTLQELTRYMVSESDNSACDKLLSLIGGP -AAVTQYLKNLGLSNVLVATTEGEMAEDELAQYRSWASPAGMAGLLVAVQKGKSMSAANHA -LLLRYLTNTTRGQARLKGLLPAGTMVAHKTGGSGTRATNDVGIITLPNQQHLAVAVFVTD -SRATEAVREGVIARIAQAAYLHw ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacterales TaxID=91347 RepID=A0A076V5H0_9GAMM ------------------------------------------------------------- --EPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGDYGTTNDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. c4a TaxID=1573582 RepID=UPI00135C27B8 ----LDQKINAVIKGKKATVGVSVLDFETPFKY-SKNGDKKLPLLSVFKFHLACAVLDQAD -KGKLSIDQKILLKKSDLLEWSPLREKYPNGDLSLGEIITYTVAQSDNNTCDFLLRMIGGP -QTVQRYMDSKGVKDLQIKYTEDDMHKDWKTQYGNESSTNSTVEVLKKFYDGKLLSKKSTD -LLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNIRMVSDISKIVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158AFF2 ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFVLSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium nematophagum TaxID=2305228 RepID=A0A3M7L7C7_9FLAO ----LDKRINSIIKDKKATIGISVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLDAVD -QGKLSLHQKILLKKSDLLEWSPLRDKYINGNIPLSEIIDYTVALSDNNGCDILLRLIGGT -QTVQKFMDSKGIKGFQIKYNEEAMHKDWKYQYENYSTPNSATQLLKKFYDGKLLSKESTE -YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGASGTGAENEIGIVTLPNGNHYSITLFVSN -STETDSVNCKIISDISKVIWDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KHC7_9BACT ------SLFQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIANCNTP------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Cellvibrio mixtus TaxID=39650 RepID=A0A266Q8C2_9GAMM -----AERLQKLEVG-QARLGVCFLDTVTGEVS-GNRIEERFAICSSFKLAMVAVCLREAD -NGRLNLEEILPYSEADLLPWAPVTREHLAKGLSIATLAQAAQEKSDGVAANLLVKRLGGP -KAVTAKFREMGDTVTRLDRYEPDLGLVLSADTRDTTSPLAYAQLVSRILTGSILRPDSRE -RLLGWARNTTTGARRLRAGLPSEWRTGNKTGTGRTNKCNDVAITFPPGKNPIIIAAYFDS -GEKIEARHEAVLAEVGKIAAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Asaia bogorensis TaxID=91915 RepID=UPI000EFC478A -hqALSDIATRYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD -RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPSSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG -GTPDETQFRRVFHDIGALA---- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Escherichia TaxID=2608889 RepID=A0A076V5H4_9ESCH ------------------------------------------------------------- -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLILV----- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853B5C2 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-HHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIAYAGEEAI--- ->[subseq from] Beta-lactamase n=1 Tax=Aquimarina spongiae TaxID=570521 RepID=A0A1M6DUK0_9FLAO ---TLRHKLGDIIQSKNVVVGVAIHGMDDKDTL-SINGHKHFPMQSVFKFPIALRVLSEID -KGNFSLEQKINIKKSELLPWSPIREKYPEGALTLAEIMKYTVAVSDNVGCDVLLRLMGGP -EAIENHFSKLGFKDFEVKINEETMQNNWDQQFLNWTTPQEANRILKAFYENSLLTKESHQ -FVWDVMKGTKTGKNRLKGQLPKETVVAHKTGWSGTAAVNDIGLVFLPNGKYFAISVFVTE -SSENFETNEKIIADITKVAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Haloactinobacterium sp. HY044 TaxID=2675753 RepID=UPI0013D5BCDF -------ALVRLEEESGVRIGAVGI--SAGARV-DHRAEEAFPMCSLFKVLAVAALLRERA -YDDAYWAEPIPFGPADLVEDSPVTSATTTWAMSPTALADAALRFSDNTAGNLLLAELGGP -EAITTFAADLGAASTRLDRWEPELNEATPGDLRDTSTPSDIALLYRALLLEDRVGALAGA -RLRDWMLRNTTSAARIRAGLNGDVELADKTGAGRYGVVNDAGVLWAGGSDPITLVILTRT -DDPAAVNDNEVVADATRIIMS-- ->[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium TaxID=1926873 RepID=A0A3C0JEG6_9GAMM ----LQAELDRITAPFDGQIGVYVLDLDSGRTA-SVNPQIGFPMASTVKVPVAVHILSLVD -EGKLDLQRPVVLKAEDIYPGGPIDTHLTPGSITVHDLLHMMLTVSDNNATDILIKLGGGT -AAVAARLHALGIEGIRVDRYIWEMLAAYDADPRDTSTPAGMAALLSRVWQGKVLKPATTA -VLESIMLDCRTGRQRLKGMLPDATPVAHKTGSVDD-VANDVGVITLPSGRGRVVIAVFEK -SEQDDAAKDRMMAQVARAAHDYf ->[subseq from] Serine hydrolase n=1 Tax=Vibrio breoganii TaxID=553239 RepID=A0A193KIS0_9VIBR ------KQVEAITAPLVGRVGFAAQLIGSDKII-AYNGDMTFPMASTYKVPAAVTLLKRVE -AGEVKLDDMVELHLDDMVADNVIAENFVHPGLSVANLIEPMITMSDNTAADFVISLAGGP -KAITDAMRKLGIKDMRIDRNIKDLFRKYEADPRDQSTPFAMLDLLMKIDSATAISEDSRD -FLIASMSRTRTGAGRIKGLLPRGTPVAHKTGTAT-GVANDVGYVTLPDGRRFAIAIYTAS -SDTPMADRDRAVAEVARTLYDYf ->[subseq from] Beta-lactamase n=4 Tax=Staphylococcus TaxID=1279 RepID=F4NA56_STAAU --nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGY -GQVKTKLIDLGDTTTHPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD -FLLNLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK -DRKDGKPNDKIVSEVAEIVLK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5T9H5_ECOLX -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKRVNGTMSLAELSAAALQYSGNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIA------------------ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Pseudarcicella hirudinis TaxID=1079859 RepID=A0A1I5TJU2_9BACT --eSFEEQVKNLAKNIKGTVGVTVMKVEEKQHF-SWNGDKHFPMQSVFKFPIAMAVLHEID -SGNCSLDKMIHVAKEDMYKYSPLRDKYPEGNVSIRDLLVYMVSLSDNNACDILLEKVVSV -SKTETFLRKLGIKGIQIKASEKEMGKDWNVQYTNWTQPVEMGRLLEIVFREKALSKSSNT -FLLKIMTETPTGLKRIKGLLPEGTSLAHKTGTSSTAAVNDVGIVTLPNGKHLIICIFIMN -ANERAEGIEPTIAAIAKAAFD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4FUC3_9BACT ----LSAEIDRVAPISGGILGIGIHHLETGREL-YVRGDDRFPMASSFKVPVAVQLLTLVD -QGKLRLDSMVTLKPSDLHPGSGTLTSLFDDPLSVRNLLELMLLISDNSATDILLRLAGGG -DPVNARLRALGVSGISVDRPTVALIAAFYRDPRDTATPKGMAALLRKIWRGEALSSKSTA -LLIDIMYRCQTGQARIKGLLPPDVRVAHKTGTLGLGVAADIGVIELPGGGHLIVTAFVKQ -STKDGPEQERAIAQAARAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter colymbi TaxID=1161202 RepID=UPI000A39CBFE ---RLAAELRIIEAASGGTLGVELYNTATGASV-GINQDKRFGHASSFKFSLAALLLQRDA -AGTIDADQKVTWTEADMLSHAPFTRERIGTGATLRELSRATQTTSDNPAANILLRYLGGP -AGLTAFWRSLGDEVSRVDRFEPEMNLVPATEFRDTTTPAAMARTVAKIVYGDVLPEKERA -ELKQWMIETETGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYLRA -RQTELAAPQAALAQVGRII---- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=UPI000D1F9FD0 ------KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS ---PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAARTLNYILTHSNMHKGNLQ -FLKELMIENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKANDEVIAKTAEIAIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Gordonia sp. i37 TaxID=1961707 RepID=UPI0009ADA55A ---SIDAQIRHIATANDVTTGVWAQDLRTGRVIaAVNCEQRYPVLSMSKVYLAAAVLDAAR -HGLLRMDSRVPVHADHIVANSPITSTYAGRTLNYSEIAKAALQYSDNTAANLMFAAIGGP -LGVTAYARTAGDGATVMVREETELNTAFPGDSRDTTTPRAWAAGLRSTMSGARLDPRDRV -TLLGWMRGTHTSDKRFRADLPAGWSTADKTGTGDYGTANDAGVLYGPDGALILLVIQTRS -ATSKATARDSVIGQTAALVTA-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium antarcticum TaxID=266748 RepID=A0A3S4WPJ3_9FLAO --qSLKKEINQIIKGKSATVGVSVLDFENNQSI-DINGNKKLPMLSVFKFHIALAVLDLID -QGKLSVDQNIYIKKEELLEWSPIRENYPEGNMTLGELIKYTVAQSDNNGCDILLRLIGGT -ETVQKFINSKSIKDFKIIYNEEKMHEGHQFHYGNWTTTNAANILLKKFYDGKIVSKSSTD -FLMKTMLETNTGANKIVAQLPKGTWVAHKTGSSGKDAENDIGIITLLNGKQYALSVFVSD -SMENETTNTKMVADISKLVFDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. LM2 TaxID=2593646 RepID=UPI00117C9E39 ----LDQKISTIIKGKKATVGVAVLSFEDNFRY-NKNANKKLPMLSVFKFHIAAAVLDWVD -QGKLSLDQKIFITKKDLLEWSPIREKFPNGNMSLDEMIYYTVAWSDNNGCDILLRLIGGT -ETVQKLMDSKGVKNFRIKNNEEQMHKGIQYLYENYTTPNSLAQLYKDFYQGKILSEKSTE -YLYNIMLNTETGTNKLKEQLPKK-VIAHKTGSSGKTAENDSGIVTLPNGNHYSIVVFISD -STESEVVNCKMVSDISKTVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. RU33C TaxID=1907398 RepID=A0A1N6PIF7_9FLAO --qELRNKINQIISTKNATAGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD -KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT -KTVQKFINQQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK -YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN -INEEMTDTEKIIADVTRAVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI0004648033 ----AEDHFAALERKYDARLGVYAMATGTSVAI-AYHADDPFAFASTYQTLAAAAVLRQRP ---LSYLDTVVRYVPEDVNSFSPVTREHIETGLTIRELCDAAVRFGDGTAAGLLMRDIGGP -EQLTAYLRSLGDTVSRIDLYEPELGGVAPGDPRGATTPRALAADYQQIVLRAALAPQQEV -LLKDWLEHGTTGADTIRAGVPAGWTVAGQAGLGGYGRACDAAVVRPPGGAPLVLTVLTDR -PGPADEPRPAMIADAARYVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D203E -----ASEIEHIEQEKNVTIGVYGMNTDNGKVY-QHNADARFAFASTYKAIASGILFNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYKDKQKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] Beta-lactamase class A n=2 Tax=Mucilaginibacter gracilis TaxID=423350 RepID=A0A495J4C7_9SPHI ----LRAQIKEIAKDAKGAVGFAMLGIENRDTL-SYNGQLHLPMQSVMKFPIAITVLHQVD -EGMLTLDQLIPIDKSDLPEYSPLRDKFPEGNIAIRELLSYMVSLSDNDACDILLKTLGGT -AVVDAYMHSFGIKQIAIKASEFQMAQAWDVQFTNWTMPKEMIRLLDIATKPNFLSKTSHD -YLWKIMEATITGPNQIKGLLPAGTIVAHKTGRSGTNATNDVGIITLPNGKHLAVAVFVTN -SAVDLPARESVIARIAKAAYDY- ->[subseq from] class A beta-lactamase n=1 Tax=Cellulomonas sp. NEAU-YY56 TaxID=2483352 RepID=UPI0013157B00 -----AAALADLEAETGYRVGVHAVDTVTGDVV-NHRADERFGYASTIKALALGVALRGAD ---PSVLDRTLPVTAEDVAGYTPVTADRVGSSMTLADLGAAAVSLSDNGALNVVLRDLGGP -AALRAVLVDLGDTTTQVDAVEPDLNRFTPGEPARTSTPRALADGLAVFALGDELDPAVRE -VYVGWLTGSTTGDATIRAGAPEGWLVGGKTGTAGYGSRNDVAVAWPPEGAPVVVAVLTDH -PDPAAAPDDTVVARAAAIVLGAy ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga niabensis TaxID=536979 RepID=A0A1N6J9Z2_9BACT --sKLRQQIAGIAATIDGQVGVSIRNLDTRDTV-TFNDSTHYVMHSVFKFHIAMTILHQVD -QGKLQLEQKIYIDKKWMVPWSPLRDSFPAGNVPLSKLLSLMVSLSDNIACDVLIDLAGGE -GAIDEYIHSLGVKDIAIKASEAKMASSWDVQFTNWSTPTAMIELLEILNKGTALSATTNA -FLWKIMKETSTGPNRLKGLLPKDVVVAHKTGTSGHAATNDVGIIFLPNGQKLAIAVFVLM -SKADDAAREGVIAKIAKAAYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gordonia sp. i37 TaxID=1961707 RepID=A0A1V4PU69_9ACTN ---SIDAQIRHIATANDVTTGVWAQDLRTGRVIaAVNCEQRYPVLSMSKVYLAAAVLDAAR -HGLLRMDSRVPVHADHIVANSPITSTYAGRTLNYSEIAKAALQYSDNTAANLMFAAIGGP -LGVTAYARTAGDGATVMVREETELNTAFPGDSRDTTTPRAWAAGLRSTMSGARLDPRDRV -TLLGWMRGTHTSDKRFRADLPAGWSTADKTGTGDYGTANDAGVLYGPDGALILLVIQTRS -ATSKATARDSVIGQTAALVTA-- ->[subseq from] Beta-lactamase n=1 Tax=Oxalobacter formigenes OXCC13 TaxID=556269 RepID=C3X8Y5_OXAFO ----LQENIDAIVKDKPAQIGVVIEGFDPHQHA-GFNENTRFPMQSVFKFPVALAVLDQVD -KGKINLDETLLLKPSDLLPHSPLREKYPEANVSIGEIINETVSNSDNNGCDILLRLVGGP -QAVDQYIKNLGIADMQIAVNEQEMHTVKDAQHKNWTTPAAMTQLLRLFHDGKLLKPDSQK -FLWTAMRDSVTAPGRLRSPLPAGTHLIHKTGTSDYSTVNDVGIILLPDGNPVFISVLISG -SKMSMMDTEKIIASVSGVAWDHf ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Photobacterium sp. CECT 9190 TaxID=2006084 RepID=A0A1Y6MAP5_9GAMM ---DLDITLRQTEQQIDGKIGVAVFDSQTNTSW-NFNGNKRFPMMSAFKTLVCANVLYDVQ -QHKLSLTNKIKVTKAGLINWNPITQNFVGADMSLQSVCGAAMLMSDNYAANLALVQVGGP -QGVTKFLRMIGDKTTRLDHFEPKVNYVEKGAQNDTTTPIAMMNTIKKLLTGNVLDSENKA -QLKFWMTNNMVSDGLARAVLPTGWKIADRSGGGVNGSRTLTAMVWNKQHKPLFIGIFIDN -SKKTLPELNQVVASISARIFNKy ->[subseq from] class A beta-lactamase n=1 Tax=Epibacterium sp. SM1969 TaxID=2663379 RepID=UPI00129581C0 ----LSQTISAIETRLDARVGVALIH--SDHSW-FHRPDTPVLLTSTAKTLICATVLAQND -QGLLSLDEHVPILQDDLLSYAPVSTRHVGGSLSIGDLCLATLDLSDNTAANLLLQRLNGP -ETVTAFLRSLGDEVSRLDRMEPALNS--PSEDLDTTTPRAMVETLSAIFFSDLLSQDARQ -QLRSWMGKGGVTQNLLREAAPKSWKIWDKSGAGKD-SRSLIAVIAPPKGSPWIAAIYISE -AEVDFQTRNAALRELSAAVV--- ->[subseq from] Beta-lactamase n=1 Tax=Yonghaparkia sp. Root332 TaxID=1736516 RepID=A0A0Q6RJ70_9MICO -------------------MGVLARDTSSGASI-AFGQDRRFGFASTMKAPLAGVFLDRVE ---GAARDEVVRWSAAQVEEYAPVTAERIDEGLTLAELAEAAVRQSDNLAFNLVLERLGGP -AALDAALAELGDETTEVVNLEPALNTIEPGSTDDTTTAAALAGTLEALLLGPTLDADDRT -LLLDWMSGNATGDTLIRAGAPEGWVVADKSGGAG-AIRNDVALVTRPDGAPIVIAVLTQR -DDPEAERDDSLVARAAEIALDAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=B8K1T9_SHISO ---------------------------------------------STSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNIIA------------------ ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. RU33C TaxID=1907398 RepID=UPI0009707774 --qELRNKINQIISTKNATAGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD -KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT -KTVQKFINQQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK -YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN -INEEMTDTEKIIADVTRAVWDYy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. AntiMn-1 TaxID=1715860 RepID=A0A192F464_9STAP -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKSIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000E67840F -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKSIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000E684E03 -----ASEIEHIEQENNVTIGVYGMNTDNSKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNTKPDDKVIAAAAEEAMK-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A2T4SVS2_STAGA ------KSIKDLETTYDTTIGVYGINTQDGKQI-EHHADERFAFASTYKAIASGILLNQLS ---PQDLNQKVTIKKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ -FLKELMIENETGDSLIKAGATKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKPNDEVIAKTAEIAIKY- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CECT 9293 TaxID=2675057 RepID=UPI001354B835 ----LDKRINSIIKDKKATIGISVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLNAVD -QGTLSLHQKILLKKSDLLEWSPLRDKYLNGNIPLSEIIDYTVALSDNNGCDLLLRLIGGT -QTVQKFMDSKGIKGFQIKYNEEAMHKDWKYQYENYSTPNSTTQLLKKFYDGKLLSKESTQ -YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGSSGTGAENEIGIVTLPNGNHYSITLFVSN -STETDSVNCKIISDISKVIWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Oxalobacter formigenes TaxID=847 RepID=UPI0002FF4C7B ----LQENIDAIVKDKPAQIGVVIEGFDPHQHA-GFNENTRFPMQSVFKFPVALAVLDQVD -KGKINLDETLLLKPSDLLPHSPLREKYPEANVSIGEIINETVSNSDNNGCDILLRLVGGP -QAVDQYIKNLGIADMQIAVNEQEMHTVKDAQHKNWTTPAAMTQLLRLFHDGKLLKPDSQK -FLWTAMRDSVTAPGRLRSPLPAGTHLIHKTGTSDYSTVNDVGIILLPDGNPVFISVLISG -SKMSMMDTEKIIASVSGVAWDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s4p13 TaxID=1367565 RepID=A0A0B5ECT0_9PSED ------------------RVYYIKLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter gangjinensis TaxID=1028742 RepID=UPI00136ABA1C ----LSAHLRIIEAASGGALGAAILDTGSGKIL-GNRLDERFAHCSSFKLSLAALAMQRSA -NGGDAFDTLLPITAEDIVSYSPVTKERVGQMMTIADLAKTTLTTSDNAAANILMRQFGGP -EAVTAFWRSVGDEISRLDRYETALNFVPPGEVRDTTTPRAMANTVRTILYGATLPSDMQQ -TLRGWMTETSTGTKRIRAGIPASWKAGDKTGTAFGSFYVDLAFAEPPEGAPLVIATYLRL -TARVEPESEAVLASVGALAT--- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A0F0KHP3_9MICO ----VADELAGLEREYDATVGVMAVDTGTGESV-AYGENRRFGFASTIKAFAAAVFLQSAS ---GAARDESVRWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLILDRIGGP -AALDDALAELGDATTEVVNDEPGLNTIESDSTEDTTTAAAFTASLARLLDGSTLSPADTA -LLVDWMSDNRTGDALIRAGAPAGWTVADKSGGAGP-IRNDIAVVTRPGHDPIIITVLTSR -NEPHADFDDTLVASAASITL--- ->[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8RX83_9BACT ---ELQKQITEIAKEANGKVGVYATVIETGERV-SLNENEHFAMQSVVKVPISMAVLKKVE -EGNLDLEEKIGVTKEDFVPRSPIRNNNPNGVLTLRELIRFAISESDGTASDVLQHRAGDA -KGVQAYIDSVGVQGFHVERTHKEFGLDWNKQYDNWATPTAVADLLKKLFSADGISDANRE -ILIRFMRESDNPANRILAGVPKGTVVAHKTGTGAAAATNDVGIITLPNGDHIVIAIFVGD -SKANAPTRESVIAKITKAIFDKw ->[subseq from] Contig45, whole genome shotgun sequence n=1 Tax=Pedobacter lusitanus TaxID=1503925 RepID=A0A0D0F642_9SPHI --sELREKLQRIVNAHSATIGFSLTDLRNGDTL-TVNGTKHLPMQSVYKFHLALAVLDQVD -QGKLKLDQKIMVKKSDLLPWSPLRDKYPNGEIPLSEILSFTVSQSDNNGCDILFRLIGGP -AKVNRYIHHLGIKDVAITATEEQMHQNDQIQFTNWTTPQAATELLGLFYAKKILSPASHE -FLCKVMTETSTGADKIKGLLPAGTLAAHKTGSSGTAASNDIGIVTLPDGKHFAVAAFVSM -TKEDEKATDLIIAELTKASWDY- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=A0A0S2K7Z9_9GAMM ---TLKADIELLLDSKRAKVGVSIWDQNAEPVF-SFNGDSKLPMQSVFKFHIAAAVLSEVD -KGKWSLEDKIKITPNDLDNWSPIRKKYPTGTLTLSEVIRYTVSVSDNVGCDILLSMLGGP -KKLEDYLHQSGIKDIAVIYNEENMQKVWQRQYENWTTANAANTALRQFYIKNLLSDKSHQ -FLWDVMKGSKTGRKTIRAGVPKDIQVAHKTGHSGTGAQNDIGIVFLPSGQHYYISVLVSD -SYETSETNQNIIAKISELTWQFf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. CBTAP 102 TaxID=2135644 RepID=UPI000D775C10 --qELRNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD -KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT -ETVQKFINQQGIKDFTIKVNEKEMAS-FEKCYINTTTPLATTELLEKFYKGKVLKKESTK -YLYQVMVETSRGLTWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHIVLSIYLKN -INEEMTDTEKIIADVTRAVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000E69920A -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSKQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=UPI00110A1B2F ---TLKPDIELLLDSKRAKVGVSIWDQNAEPVF-SFNGDSKLPMQSVFKFHIAAAVLSEVD -KGKWSLEDKIKITPNDLDNWSPIRKKYPTGTLTLSEVIRYTVSVSDNVGCDILLSMLGGP -NKLEAYLRQSGIKDIAVIYNEENMQKVWQRQYENWTTANAANTALRQFYIKNLLSDKSHQ -FLWDVMKGSKTGRKTIRAGVPKDIQVAHKTGHSGTGAQNDIGIVFLPSGQHYYISVLVSD -SYETSETNQNIIAKISELTWQFf ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. RCC1885 TaxID=1647104 RepID=A0A0P7AD35_9SPHN --eQLAAQIDGLEAASGGRLGLALFSQDEGLLF-AHRGAERFAMCSTFKLALAAMTLETSG -----VREERLDFGEDDILSYAPYAKERAQIGMSGLEAAHHAVTLSDNTAANLLLARLGGP -EAFTAWLRDAGDRVTRLDRNEPALNENAPGDPRDTTTPEAKAELVGNLLWGDRLSATDRS -ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPAGSHYVLAAFLDR -PTGTSAEADAVLADAARAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WX07_9BACT ----LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGSLRFPMASVYKLPIALRVLQRVD -RGELRLNAPVTLSTHDFRPHSPIVEFANNKPLPLERLLELMLGESDNSASDALLRLAGGP -AAVTNRMQALGIMGINVSRPEGQLILAYADDPRDTSTPDAMADLLVRIQRRDVLEPASME -RLLQITTATQTGPARLKGLLPIGTVVAHKTGTMG-GTTNDVGIVTLPDDGHLAIAVFVKA -STKDVPERERAIAEIARTVYDFf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=A0A1E5TG47_9STAP -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTSTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIAYAAEEAI--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=UPI000E697F1C ------KSIKDLEATYDTTIGVYGINTQDGKQI-EHRADERFAFASTYKAIASGILLNQLS ---PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ -FLKELMFENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKPNDEVIAKTAEIAIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000935D6A7 -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A345N875_ECOLX ----------------------------------------------------AAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGPTNDIAVIWPKDRA---------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. RCC1897 TaxID=1812182 RepID=A0A2P0B2D6_9SPHN --eQLAAQIDGLEAASGGRLGLALFSQDEGLLF-AHRGAERFAMCSTFKLALAAMTLETSG -----VREERLDFGEDDILSYAPYAKERAQIGMSGLEAAHHAVTLSDNTAANLLLARLGGP -EAFTAWLRDAGDRVTRLDRNEPALNENAPGDPRDTTTPEAKAELVGNLLWGDRLSATDRS -ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPAGSHYVLAAFLDR -PTGTSAEADAVLADAARAVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga terrae Kim and Jung 2007 TaxID=408074 RepID=A0A1H3YVC1_9BACT -----RKEITGTAASVKARVGVSVLS--DRDTL-TIRGNKRFPMQSVFKFHLGLLVMHLVD -EGKLSLQQQVHFTPEDMALWSPIAKKYPGGNLSLEEVLKSTVSTSDNIGCDKLFELVGGP -AALNKYLHGLGATDLSIVATEKEMHADWDVQYRNWTTPREATRLLKAFDEGKILKPASRD -VMMRFMTTNTNINDRLSGLLPAGTKVAHKTGTSDTAATNDIGIVALPDGRHYYIAVFVSD -SWEQGAKNNRVIAEISRKAWDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Larkinella sp. BK230 TaxID=2512173 RepID=A0A4R8CC95_9BACT --qRLNQELERIAKLAKGKVGLSAVHLESGKQI-SMNLQERFPMASTVKVAIAVELLTKIE -KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV -EPVRARLKALGIEGMSVDRTIVQLIAKLEQDPRDTSTPAAMVNLLTQIYQAKALKPESRD -LLLAVMERCRGGLARIKGYLPPETVVAHKTGSLNSSATDDVGIITLPGDGHIAIAVFITS -SSQPLAEREQTIAHLSRTVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Francisella sp. TX07-6608 TaxID=573568 RepID=A0A1S2WWX4_9GAMM ---QITNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKHSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILNKKHRL -MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DBB930 ---SLRSQLERTASAAQGKVGVAATLLETGESI-ALQGDQRFPMQSVYKLPIAMVALHLVD -QGKLTLDQPVRVDKVEYVSHSPLRDKSPDGTVSVSELLRYAVSESDGSASDVLMRLVGGP -NVIMTYLNSLGIKDMIVANTEKELGADNAVQYRNWAKPTEAVALLRLIQQGRGLSESSRA -LLLRIMTETETGLHRLKGQLPAGTVVAHKTGTSWTAATNDIGLITLPSGRHIALAVFVSD -ARADQKTREAVIANLSRTIWNYw ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QFM0_9SPHN ---RLEAKLRIVEAGAGGQLGVFALDTQTGLGL-GHRQTERFGHCSSFKASLAAMVLQLDA -DGTISADEHVRWTRDQLMAVSPFTTERLEQGATLHELAEATQKYSDNAAANILLARLGGP -QALTAFWRRMGDDASRLDRTEPELNNVPPGELRDTTTPRAMATTLARMLYGGGLDAQAGE -RLKGWMHDTPTGLRRVRAGLPEGWHAGDKTGTSIGGLYVDIGFIEPQQRAPLTFATYYRA -PTAMDPVSEAVLAQAGSIIA--- ->[subseq from] Beta-lactamase n=3 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A257WV64_9CAUL ---DLTAQFQTLADQAPALLGIAVRDAQTGQTI-AFNGQTRFPLQSVFKAPLGAAVLAEVD -RGRIRLDEVITIRDIDLSPFSPIADAWPGRTYTVAELLERASGASDNTAADVLMKRIGGP -GALTAWLSQKKIMDFRIDRYERQLQPDYLADPRDTATPVAAVRFLAALRAGKLISKASTD -RLLGIMTATTTGPGRLKAALPDGASLAHKTGGARTDASNDIGIYELKDGRRFAVAVFLSG -STASDEARDAVIAEVGRIVLK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=A0A1B8ZR25_9FLAO --kDLKNKIHEIISAKNATVGVSLKGIEDQDTL-SINGNKKTPLMSVFKFHIALAVLNQVD -KGKLKLDQKFFIKKEELLPWSPIRDQYPKGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -AAVQKFINRQGIKDFTIQVNEQQMSS-FDKFYLNTTTPLATTELLEKFYNGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIVKLPDGKHYILSVYLKN -INEEMADTEKIIADISRAVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2D9PCG8_9SPHN --qDLAARISEIETASGGRLGLALHSPDKGLVY-AYRGDERFAMCSTFKLALAALTLDTPG -----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP -DGFTRWLRSMGDEATRLDRNEPALNGNAPGDPRDTTTPTAHADLVGTLLWGDRHAQADRA -LLQEWLVETTTGMNRLRVGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR -ADGSASDAEARLAEAARAIAD-- ->[subseq from] Beta-lactamase n=1 Tax=Francisella adeliensis TaxID=2007306 RepID=A0A2Z4XYM5_9GAMM ---KLAKDIKKIEVKHGGKIGVYTINRNNWKNF-SFQSSFYFPVCSTYKILVVGAILKQNM -TDKNLLNEKIKISPNSIAGYSPITNKHLNKKMTVAELCHASI-LSDNTATNLLVEKLGGL -EKLSEFNLSLGDHATKIADKEPEINDVNLRTNINKTTPKIMTRDINKLAFNDILDKKHRL -LFKKWLKDNDTGKNRITAGAPSNWLVGDKTGTCEYGTTNDVAIIWPNNSRAIAMSVFYTQ -TEKNAKPNEKIIKEVSQLVLK-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=A0A495RSS6_SPHMI --kAVDTEVERLAAGAGGVVGIAAWRLDKGSRV-LFNADASFPMASTYKVPLAGKIFDMVD -KGQIRLDTMLDVPQEMMSPSEVIADRFIHSGLSVHNLLEVMLTQSDNTATDVLMKAAGGP -QAVTAWARAQGVTAMRVDRDTNRLLRTFDADPRDTASPAAMATLLTRMFAGKALSPESTK -AFTAIMERCRTGAARLPGQMPPGTIVAHKTGTIG-GTVNDVGMVSLPDGTGVVIAAYVKT -SAAPTADRERAIAEIARTIRDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000853BD06 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINETDIVEYSPVTENYIGKQMTFKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGAPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HCR5_9BACT --dQLRRQIEEIVSTKRAVVGVSISDAGGKSIV-LVNGDKRFPMQSVFKFHIGLKMLSEID -KGTFSLDQKIEIKKSELLPYSPIREKYPEGTLSIAEILEYTVSMSDNVGCDVLLKLLGGP -LAVENYFAGNKFNNISIKINEEVMQGNWDRQFENWTTPKAAGNVLRAFYARKLLSAKSHE -FIWKVLRETSTGANRLKGQLPAGTVVAHKTGWSGTAAVNDIGIVFLPNGKHYFISVFVTE -SKEDFAANEKIIADVSKAAWDYf ->[subseq from] Gll0595 protein n=1 Tax=Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) TaxID=251221 RepID=Q7NN19_GLOVI ----LHRQIARLAERLGGRVGAAIVHVESGRAI-ALKGAERFSMASVYKLPIAIAILDMVD -RGELDLTRKLTVKASDLRPGSPLAERRDAVGLSVRELIELVMIYSDNSASDLLFDLAGGG -EAITKRLQTLKIAGLRVDRPELELLAQYRLDPRDTSTPEAIGRLLVRLQRGDILKPESNR -LLLGIMERCATGVQRIPGNLPAGTIVAHKTGTNA-GGNNDAGIITLPGKGHLAVAVFVQT -PGQPSAERERLIAEIARAGFDFf ->[subseq from] Beta-lactamase class A n=1 Tax=Shimia aestuarii TaxID=254406 RepID=A0A1I4SHV0_9RHOB ----VAAAIEQFAAKHVGRLGFAAQEIGGDEVI-ALNGDETFAMASTYKMAIATAIMDRVD -KGELSLDQMVDITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA -AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRD -FLIDIMSRTRTGAARLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAVAVFTKS -SVSSEADRDRAIAEVARSLYDYf ->[subseq from] Beta-lactamase n=1 Tax=Pararheinheimera mesophila TaxID=1547515 RepID=A0A3P3QQG0_9GAMM ----LKEQIESVVSGKKATVGVAVWGPDDLEPL-LVNPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQSVTVNRARVLQWAPLMKDYQGDEVPLQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYLHSIGIKETAVVANEAQMHADDQVQYQNWTSMKAAAQILKKFEQKTLLSETSQA -LLWKWLVETTTGPERLKGLLPAGTVVAHKTGYSGTAATNDIGVIVLPDGRPLLVAVFVKD -STESTRTNEAIIAQVAELAYQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Chitinophaga sp. K20C18050901 TaxID=2291814 RepID=A0A3E1P3I9_9BACT ---ALRKTIDSIVTHSKAHIGVSALLLETGDTL-SYRGNDHYPMQSVYKFPISFAILHQVD -LGKYKPDQKITITSDDIMPHSPIREAHPHGGMTIREISRYNIQESDGTACDVLLRLLGGT -KKTNAYIRSLGVTGINIATTEKEQQQDDTTQYHNWATPIAITQLYKVFLRNNVLSKQSYD -ILWKDLAESHPGAKRIKGLLPPGTVVAHKTGTSGTAATNDSGIIILPNGKHLILTIFVSD -SKGSEAEREGWIAQISKAVYDHf ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium 12-68-11 TaxID=1970586 RepID=A0A257YDT6_9SPHN -----EAALAALEARSGGRLGACIIDTATGRTA-GWRSSERFAHCSSFKLSLAALVLQGAQ -AGRWQLDHRLHWTQGDLMGNSPVTSAHVAEGLTAAELARATLVTSDNAAANVLLRWLGGP -QAMTAFWAAIGDTTSRLDRLEPDLNVVPPGSVLDTTTPAAMAATVARLVTGDVLDEAGRA -MLMSWMVEVQTGTRRLRAGFPAGWVAGDKTGTGLSTIYVDLAFGGPAARAPLVVAAYFV- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD47_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKID -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVHLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHNTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXU9_9BACT --sSLERAIKRLADNSGGVVGVSAIHVETGRRV-ALNGAMRFPMASVYKLPIALQLLHKVD -RGELRLSDSVTLSEQDFRPHSPIAEFANHKPLSIERLLELMLGESDNSASDKLLALAGGP -AAVTARMRALDITGLDISRPEGRLALAFADDPRDTSTPDAMAQLLVRVERREVLEPASME -RLLQITTATQTGPLRLKGLLPAGTPVAHKTGTMG-ATTNDVGIITLPDGGHVALAVFVKG -STLDVPSRERVIAEIARTIYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI0002DAEEFC ------------------------------------------------------------- -------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI -QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK -NKKGAVSPDSIIERITRILM--- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CECT 9393 TaxID=2675058 RepID=UPI001360AFBB ----LDKRINSIIKDKKATIGLSVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLHAVD -QGTLSLHQKILLKKSDLLEWSPLRDKYPNGNVPLSEIIDYTVALSDNNGCDLLLRLIGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWKYQYENYSTPNSATQLLKKFYDGQLLSKESTE -YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGASGTGAENEIGIVTLPNGNHYSITLFVSN -STETDSVNCKIISDISKVVWDYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A345N867_ECOLX ----------------------------------------------------AAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSRGYGTTNDIAVIWPKDRA---------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Eudoraea adriatica TaxID=446681 RepID=UPI00035E5CB4 --kSIAQKIEKLTEGLVGRIGVAAQELSSGLNV-SINGDENFAMASAYKIAIAAKVMDLVD -KGELSLDQMVEVPQDMYVAVVAIAERFPYSGFSLANLIYPMITESDNTATDVCLQLAGGP -TAVTENLRRLGITDFRVDRSVREILMNFEADPRDHTTPNAYLQLLLAIDGGTAMSPKSRE -FLLGVMSRTRTGAGRLKGLLPKGTPVAHKTGTLG-GVANDVGYITLPDGRQFAIAVFTNS -SKTPASDRERAIAEVARALYDFy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A512S8G6_STAGA ------KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS ---PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ -FLKELMIKNETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKPNDEVIAKTAEIAIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000D1D3F73 -----ASEIEHIEQENNVTIGVYGMNTDNGKVY-QHNADERFAFASTYKAIASGILLNNTP ---NNKLNKKIKINEQDIVAYSPVTEKYIGKTRSLKSLVQASMLQSDNTANNKIINEIGGI -EGFNKELKSLGDYISKPQRLEPDLNDYDPTKIADTTTPKAAATSLNKLLTSKQMDKENQA -LLKQVMIENETGDSLIKAGVPKHYTVGDKSGQGTYGTRNDLAFIYTDKHKPIILAVYTKQ -DQKNAKPDDKVIAAAAEEAIK-- ->[subseq from] TLA family class A extended-spectrum beta-lactamase n=1 Tax=Klebsiella michiganensis TaxID=1134687 RepID=UPI00102009E3 --dSLKNSIEKYLKDKKAKVGVAVLGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLQPWSPLKDKYPNGNLSFSEIIKSTVSHGDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. LCT-H4 TaxID=1914308 RepID=A0A1S2MKQ8_9STAP -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI000B08C16B ------------------------------------------------------------- -------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI -QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK -NKKGAVSPDSIIERITRILM--- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter litoralis TaxID=39960 RepID=A0A074MHP5_9SPHN ----MQATLRLIEAKAGGTLGVDIYDTQTGVSV-GLNRDRRFGHCSSFKLSLAAMVLALDA -ADEIDASRRVTWTKDDLMFVSPFTEKRLAEGASLLELAEYTQKYSDNTAANVLLRELGGP -AALTGFWRSIGDGVSRLDRTEPELNNQPVTEYRDTTTPAAMARTVAKLLYGDVLPEPSEA -LLRQWMIDTPTGARRVRAGLPEGWVAGDKTGTSIGSLYVDIGFARPPEHPPITFATYYRA -RETHDPASEAALASVGEVI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga dinghuensis TaxID=1539050 RepID=A0A327WD70_9BACT --qSLRAEIAAIAGKIPAKVGVSVRVLETNDTI-SFNRDLRLPMQSVYKFPISMAVLDQVD -KGRLTLHQPIKIEKADLTTVSPLRDKYPNGGLTIDELLDYNIRSSDGSACDILLKVLGGP -AAANKYIHQLGIKDINIATTEEAQQNDAKTQYKNWCTPSAMTLLLEKFYLKPLLSDSSKR -YLYHLMATSGPGKRRLKAQLPAGTEIAHKTGTSWTAATNDAGIITLPNGKHVAITVFVSD -AKASEAEREGTIAAIAKAVWDAy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. IMCC26285 TaxID=2509718 RepID=UPI001365FF42 -----ETALAELERSAGGKLGATILNTRTGQSI-SHRGGERFGMCSSFKLALAALILRKAD -GGELDLDSFVPITSSDMVYFAPVVTENLAKGMTIGAMAEAAQVFSDNVATNKLLAILGGP -AGFTAAMRAIGDVQTRLDRLEPEMMLVDVGDPRDTTTPFAMAHTVAKMTTTNWLSVGART -KLLGWMEATKTGSKRIRAGLPADWRSGDKTGTGMPDRYNDIAIAWPNKGAPIIITGYYES -PVKSRDEDQAVLAELGKI----- ->[subseq from] Serine hydrolase n=1 Tax=Halioglobus lutimaris TaxID=1737061 RepID=A0A2N5X5X1_9GAMM ----VATSIEQFAAKLVGRIGFAAQEIGSDEVI-ALNGDETFPMASTYKVAIATAVLDRVD -KKELSLDQLVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA -AAVTENLRRLGVTDFSVDRTTGEIIGDFEADPRDHATPLAMLKLLLAIDSSTAMSAESRD -FLIDVMSRTRTGAARLKGLLPKGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga rhizosphaerae TaxID=1864947 RepID=UPI000F805A89 ---SLRLQISAIAAEAKGVVGVSIQNFATGDTL-TLNDTARLPMQSTFKFPIAMTVLKQVD -EGKLTLEQKLPVTPDDLFEYSPLQDSFPKGTKTIANLIYLMVAQSDNIACDVLIRKVGGC -KVINDYVHSLGVKNIEIVMTEEEMNGGFDLQFKNWAQASAYSQLLDILRKGTALSKPSND -FLMNTMLATTTGKNRLPGLLPAGTPVAHKTGSGSTKATNDAGIITLPNGQQLAVSVFVSM -SAADEATRDAVIAKIAKAAYDHy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. YR203 TaxID=1500291 RepID=A0A1M5GKZ4_9FLAO --sALEQKISSITQGKKATVGVSVLGFENNFKY-SKNGDKKLPTLSVFKFHIACAVLDLVD -QKKLSLEQKLFLKKEDLLEWSPIREKYPEANLSLSEILDYTVSLSDNNGCDILLRLIGGP -QTVQKFMDSKGVKDFQIKYNEDEMHKNWKALYENYSTPNSAVQVLKKFYDGALLSKKSTD -YLMQIMLGTKTGTNKIIEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAIFVSN -STETEVVNCKIVSDISKAVWDDf ->[subseq from] Class A beta-lactamase n=2 Tax=Novosphingobium sp. FSW06-99 TaxID=1739113 RepID=A0A102D8B4_9SPHN --------LAALERRAGGRLGVAVRDTASGRGF-GWRQDERFAHCSSFKLSLAAMVLAQID -AGQARGDEVLAYSVLDILPASPVTEAAAGKELPILTLAEAAVERSDNLAANLLLARFGGP -AALTAFWRTLGDDVSRLDHHEPDLNRVAPGAVHDTTTPTAMAQTLGRLLTGPVLSGGSRA -TLWGWMKACSTGLGRLRAGLPEGWQAGDKTGTWNDGKVVDLALVLAPDGAPLAVTAYYEP -TGTPRPADEAVLAAVMRIATD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium taihuense TaxID=1141221 RepID=A0A1G9RST5_9FLAO ----LDQKINTIIKGKKATVGVSVLSFEDHFRY-NKNANKKLPMLSVFKFHIAAAVLDWVD -QGKLSLDQKIFITKKDLPEWSPIREKFPNGNMSLNEMIYYTVAWSDNNGCDILLRLIGGT -ETVQKFMDSKGVKNFQIKNNEEQMHKGIQYLYENYTTPHSLAQLYKDFYQGKILSEKSTE -YLYNIMLNTETGTNKLKEQLPQK-AVAHKTGSSGKTAENDSGIVTLPNGNHYSIVVFISD -STEPEKVNCQMISDISKTVWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=A3KEX6_STEMA -----ATDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ -QLADWLIDNETGDACLRAGL---------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Tropicimonas sp. IMCC6043 TaxID=2510645 RepID=A0A4V1V657_9RHOB ---SVGAAIERAAAGLAGRIGSAAQEIGGDQVI-AFNGDESFPMASTYKVAIATAIMDRVD -RGELSLDQMVDITPDMMMIDAALSDTHPGVQLSVANLMEIMITESDNTATDTLIGLAGGA -AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRD -FLIDVMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEIARSLFDYy ->[subseq from] Beta-lactamase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A317I174_9PROT ---------AQAARTVDGKVGASVLVVETGERA-GVRAADRFPMQSVYKFPIAMAVLHLVD -AGKLKLDDPVTVARAELVPHSPIRDAHPQGDMPLRDILRYAVAESDGTASDVLVRLAGGC -GSVAAYLRDLGIANVTIATTELEMSSGDMVQYRNWATPDGMTGLLAAFQKGAGLSAESRA -LLLQWMTESTPGPKRLKGLLPAGTVVAHKTGTSGTRATNDVGLITMPDGRHLAVTVFVAD -SRAPLEAREGVIARVARMAWDQw ->[subseq from] Serine hydrolase n=1 Tax=Larkinella rosea TaxID=2025312 RepID=A0A3P1BPM5_9BACT --qRLNQELERIAKLAKGKVGVCAVHLESGKQI-SLNLQERFPMASTVKVAIAVELFTKIE -KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLRLVGGA -EPVRARLKALGVEGMSVDRTIIQLIAKLEQDPRDTSTPAAMVNLLTQIYQAKALKPESRD -VLLAVMERCRGGLARIKGFLPPETVVAHKTGSLNSSATDDVGIITMPGDGHIVIAVFITS -SAQPLAEREQTIAHLSRTIYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium humi TaxID=493375 RepID=A0A1H6AFS0_9FLAO ---NLKAEIQNVIKDKNATIGVSILGFEKPFEL-NINGDKHLPMQSVFKFHIALAVLNLVD -TGELNLNQKIFIKKSDLLEWSPIREKYPNGNLTLAEIIKYTVAQSDNNGCDILLKLIGGV -QTVQDFTNSKAVKDFQIKYNEEKMHQDWNAQYENYSSTNSLVNVLKAFYNDKIVSKSSTD -FLMKILIGTTTGQNKLKALLPKTAIIAHKTGSSGTGAENDMGIVTLPNGNHYAICVFVSN -SKETEAINCKIIADISKLVYE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s3p12 TaxID=1367561 RepID=A0A0B5ECR8_9PSED ----------------------IELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000C33B09A -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLN -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=A0A4U8WA17_9FLAO ----LDQKINTIIKGKKATVGVSVLSFEDHFRY-NKNANKKLPMLSVFKFHIAAAVLEWVD -QGKLSLDQKIFITKKDLPEWSPIREKFPNGNMSLNEMIYYTVAWSDNNGCDILLRLIGGT -ETVQKFMDSKGVKNFQIKNNEEQMHKGIQYLYENYTTPHSLAQLYKDFYQGKILSEKSTE -YLYNIMLNTETGTNKLKEQLPQK-AVAHKTGSSGKTAENDSGIVTLPNGNHYSIVVFISD -STEPEKVNCQMISDISKTVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Asaia sp. As-1742 TaxID=2608325 RepID=UPI00141D7ED8 ----------RYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD -RDEDDLTRRIAFRESDFKEWAPVANRNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG -GTPDETQFRRVFHDIGALA---- ->[subseq from] Beta-lactamase n=1 Tax=Chryseolinea flava TaxID=2059302 RepID=A0A364XYF2_9BACT ---RLKNSIKKILSNKSAVVGVSIIGTNGKDTL-SIHGDRRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIEISKDELLPYSPLRDENPNGGFTIEKLIQYSVSISDNTACDALIRLIGTP -KTVEAYIKRSGINDIQITFNEEDMQAKWENMFQNWTTPKAASETLRLFYESNLLSKSSYD -FFWKTNRETTTGKMRIKGQLPAGTIVAHKTGSSGTAALNNIGIVFLPTGEYFIISVFVSE -SKEDSATNEKIIADIAKATYDFy ->[subseq from] BlaZ family class A beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A657ZLF9_9STAP -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -EDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] class A beta-lactamase n=2 Tax=Agromyces sp. LHK192 TaxID=2498704 RepID=UPI000FD98E8A -----ARALADLEREASVSIGVVAAVRGERRAF-RYRADERFPMCSLFKTLAAASLVQQRG -YDDVYWTTPIPYTRADIVIDSSVLGENPPMQASPDLMCDAAVRASDNTAGNLLLRELGGP -AAITAFAASLGARNTRLDRWEPDLNQALPGDLRDTSTPDDIAMLYEALLLDDAAGVLASA -RLREWMLRCQTSGKRMRNGLDGPYELADKTGGGSYGVVNDAGVLWRPGHPPMTIAIMTRT -DRSDATRNDAVVAEATRIVV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter duraquae TaxID=425511 RepID=A0A4R6IKH8_9SPHI ---LLRNEIASIALSAKGRVGVAMEVLEDRDTL-SYHGGSRVVMQSVFKFPIAIAVLHQVD -LGKLKLDQMLHIIKEDLPKYSPLRDKYPEGNLPVSELLSYMVSLSDNDACDILLNKIQLK -SEVERFIHNVGIKDIEIRATEAEMMANWDAQYTDWTTPDAMLKLLRISYTDTILRPSTKS -FLWEIMEATSTAPKRMKGLLPPGVIVAHKTGTSSTNATNDVGVITLPNGKHLAIAVFVTD -SYADPVTRDLVIAKITKAAYDTf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Mucilaginibacter polytrichastri TaxID=1302689 RepID=A0A1Q5ZZ70_9SPHI --eTLRNHIAEIAKEAKGIVGVSVLNIETGDTL-SYNGYKHFPMQSVMKYPIAITVLHEID -KGKFTIDQPIHVDKSDYYDYSPLKDKYPEGNVSIKELLSYMVSLSDNIACDVLLKTLGGT -DKVDAYMHTIGINNIAIKASEYQMAQAWDVQFTNWVQPKELTRLLKISFKPDFLSPPSYA -YLWKIMQATSTGPKQIKGLLPEGTIVYHKTGRSGTNATNDVGIITLPDGIHLAIAILLSN -SSVDMPTRESVIARIAKAAYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1D428E -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMSLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6C7_9BACT ---DVSQAFKLAKQKSQGNLGAAVMDFQTGECI-DINGDLPFPMQSVYKLPIAINVLSQVD -KGTLKLDQRIQVTPADYVTHSPLRDKHPDGITTLNSLLELMAGESDGSACDVLLRLTGGP -RATSRFLQEIGTTAVHVLNTEKEIGANSSVQYANTATANATVGLLKTLYNGRTLSEESRS -RLLNIMTNTPTGPRRIKGKLPPTYSVAHKTGSSRTAATNDVGIITFPDGRAVAIAVFVND -SRADSATRDEVIADVAAAALKYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium arachidis TaxID=1416778 RepID=A0A1M5H898_9FLAO ----LDQKINSLISNKKATVGISVLDFENGFKY-SKNADKKLPMQSVFKFHIAATVLDYVD -KGKLSLDQKIVLNTSNLLGWSPLRDKYPNGGVPLSEILEFTVAKSDNNGCDIMLKLLGGT -QTVQKFINSKGIKGFQIKYNEAEMHKDWNLQYENYSTMNAATDALRKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPKNTPVARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN -STETEEVNCRMISDISKLVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. LM2 TaxID=1938605 RepID=A0A1S6ET39_9CAUL --------LSALEQANGGRLGFVAHDLGTGRRL-TARGDERFVYCSTFKMYLSAATLMRVQ -AGHEQFDRLIPMTAADMVSHAPVTEPAIGSSLSVERLMQAVVEVSDNPAANLLLKALGGL -DPMRAFYRGLGDDSTTVDRFEPEMNRV--DGIKDTIQSLQSATNIQRLFLDAALSAESQT -RLLGWMFASPSGADRLKGGAPAGWRVAHKTGTGGYGPTNDIGILYPPSGEPVIVAAYYHA -TPTSDAQNAAVIADATRLAL--- ->[subseq from] VEB-PER n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCW7_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAALDKLV -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=3 Tax=Francisella tularensis TaxID=263 RepID=A0A0E2ZJR0_FRATU ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQIMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X0I0_9BACT --qTLSKEIVTLAKKYSADVGVGII-TPEGDTV-SVNGNRRYPMQSVYKFHLALYILDQVD -QKKLSLRQEIILTKRDLLPHSPLRDSRIGMRVTLQKLLQYTVSYSDNIGCDILFRLAGGP -SKVHDFIQAHGVSDVAVIYTEEEMHADWEKQFANYSTPKSMVLLLDKFRKGEILSPSSTK -LLMELMQNTTTGTKRLKGNLPEGTIVGHKTGTSGYRATNDAGIVTLPGGRTYSIAVFVSK -SRETEETNERIIAEISRMVYDN- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WYB9_9BACT ----LEKQFEEIARKSGGRVGVRAMLLATGETF-SLNENERFPMQSVYKLPIAMAVFGRIE -AGTIKLEQMLRIGGGEVLKGSTALEKYPDGTRSVEELLGLMVSESDNTASDALLRLAGGP -REVMNYLKKLGINDMVVANFEKEMHADWQAQYRNYATPSAAVELLRAIDEANGISPPNKT -RLLKFLTESPTGPRRLKGLLPEGAVVAHKTGTSATRATNDIGILTLPDGRRFAIAVFVAD -SSADQATREETIARITRAAWTYw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346QRV5_KLEPN --------------------------------------------CSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNPI------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. HMWF035 TaxID=2056868 RepID=A0A2U0E0X1_9FLAO --sSLETQINSIIKNKKAMVGISVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLDYAD -KGKLSLDQKVSLNQSNLHEWSPLREKYPNGGVPLSEIIEYTVAKSDNNGCDILLKLLGGT -QVVQKFMNIKGVKNFQIKYNEEAMHKDWNAQYENYTTMNSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGINKLIEQLPKDTPIARKTGSSGTGAENEIAIITLPNGKHYAIAVFVSN -STETAEVNCRMISDISKTVWDYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X3Z9_9BACT --rDLQARIEQLVDFAKGRVGVAAELLETRAAV-SVNAREQFPMQSVYKLPISMAVMKQVD -AGKLKLDQKVQITKADYIGHSPIREKYPNGALSLTELIRFALSESDGTASDILMRLAGGA -EAVQAYLTELGINKMDLVDPEMALAKDPSVQYRNYARPAAAIELLRSLHEKRGLSDSAQA -LILKCMVESTPGAKRLKGLLPAGTVVAHKTGTSGTAATNDIGIITLPDGRHLAIAVFVSE -SPADLDTRERVIAEIAKAAYEKf ->[subseq from] PER family class A extended-spectrum beta-lactamase n=1 Tax=Rheinheimera sp. LHK132 TaxID=2498451 RepID=UPI000F8EEABB ----LKEQIETIVTGKKATVGVAVWGPDDLEPL-LLNPFEKFPMQSVFKLHLAMLVLHQVD -QGKLSLNQSVTVNRAAVLQWAPIMKEYQGDEVPLQQLLQYSVSHSDNVACDLLFELVGGP -QALHAYIQSLGVKEVAVVANEAQMHADDQVQYQNWTSMKAVAQLLKKFEQKKQLSETSQA -LLWKWMVETTTGPQRLKGLLPVGTIVAHKTGTSGTAATNDAGVIMLPDGRPLLVAVFVKD -SAESERINEAIIAQVAQAAYQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI0013569E8F ---RLDHELERIAKLAKGKVGVSAVHLETGKHI-SLNLKELFPMASTIKVAIAVQLFTKIE -KGELSLMTMVDLQPSDYHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQKRMNALGIKGMSIDRTIIQLIARLQKDPRDTSSPEAMVNLLTQIYTGKALKPESRD -LLLAVMERCRGGVARLKGYLPAGTVIAHKTGSLNASATDDVGIITLPDGGHVAIAIFVSE -SGAELSEREQTIAHISRSIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000E68826C -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -EDKEGTPDDRVIAKAAQIAIK-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter polytrichastri TaxID=1302689 RepID=UPI000942441F --eTLRNHIAEIAKEAKGIVGVSVLNIETGDTL-SYNGYKHFPMQSVMKYPIAITVLHEID -KGKFTIDQPIHVDKSDYYDYSPLKDKYPEGNVSIKELLSYMVSLSDNIACDVLLKTLGGT -DKVDAYMHTIGINNIAIKASEYQMAQAWDVQFTNWVQPKELTRLLKISFKPDFLSPPSYA -YLWKIMQATSTGPKQIKGLLPEGTIVYHKTGRSGTNATNDVGIITLPDGIHLAIAILLSN -SSVDMPTRESVIARIAKAAYD-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium carnis TaxID=1241979 RepID=A0A3G8XW18_9FLAO --sDLKKDINQIIKGKNATVAVSVLDFETNKSL-SINGNKKLPLLSVFKFHIALAVLDQVD -QGKLSLDQNIPVTKAELYEYSPFRKEFPDGNKTLAQLLRYMVAKSDNNITDILINLIGGT -KTVQKKMDKSSVKNFTIIADERKMHEGWEYLYWNTSTTNSLNAVLQKFYKGKLLSKQSTD -FLMQTMLETTTGANKLVAQLPKNIPVAHRTGSSGTAAENDIGIVTLPNGKHYAISILVSD -SMESENTNTKMIADISKIVFDYf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter dokdonensis DSW-74 TaxID=1300349 RepID=A0A1A7BG25_9SPHN ---RLEAELRRIESEADGTLGVELFDTATGLAV-GINETRRFGHASSFKLSLAALLLERHA -AGAINADKQVRWSEADMVHHAPFTRDRIGTGATLRELARATQITSDNPAANILMRELGGP -AGLTAFWRSIGDNISRVDRIEPEMNNVPTSEFRDTTTPAAMARTVAKIVYGDVLPPAERA -ELKGWMVETQTGRNRVRAGLPEGWLAGDKTGTSGY-NYIDIGFAEGPKGAPITFACYFRA -RQEMLPRGEAVLAQVGRLI---- ->[subseq from] Class A beta-lactamase n=1 Tax=Cellulomonas sp. NEAU-YY56 TaxID=2483352 RepID=A0A3M2JDK0_9CELL -----AAALADLEAETGYRVGVHAVDTVTGDVV-NHRADERFGYASTIKALALGVALRGAD ---PSVLDRTLPVTAEDVAGYTPVTADRVGSSMTLADLGAAAVSLSDNGALNVVLRDLGGP -AALRAVLVDLGDTTTQVDAVEPDLNRFTPGEPARTSTPRALADGLAVFALGDELDPAVRE -VYVGWLTGSTTGDATIRAGAPEGWLVGGKTGTAGYGSRNDVAVAWPPEGAPVVVAVLTDH -PDPAAAPDDTVVARAAAIVLGAy ->[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI00135E5D78 ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas sp. MYb238 TaxID=2040281 RepID=UPI00129200E2 ----LQRELERLVAPFDGKVGAYVLDLRSGRHA-QVNGDAGFPMASTVKVPVAVHILAVVD -EGRLDLRQQVVLQASDIYPGGPM-DTHLTAGITVRDLLHMMLAVSDNNATDILIRLGGGP -AAVDARMRALGIDGIRVDRYIWEMLALYNADPRDTSTPAGMAALLRRIWEGRALRPDTTA -VLKAILLDCRTGQARLKGMLPDATPVAHKTGTVDE-VINDVGVIVLPGGGEVVVAVYLVS -GA-SDQARDRMIAQVARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=A0A0N7JH99_9CAUL --kALTQSLQAVADRAPGQLGVAVCDIQTGQTV-TFNGDRRFPLQSVFKAPLGAAVLSGVD -RGEIRLDEVITIRDIDLSPFSPIAESWPGRTYSVAELLEAASGASDNTAADVLLNRIGGP -GALTAWLTQKAIPDFRIDRYERQLQPDYLTDPRDTATPLAAVRFLAALQAGHLISRASTE -RLLAIMTATRTGQGRLKAALPEGASLAHKTGGARTDASNDIGLYRLKDGRQFAVAVFLSG -STAPEDARDAAIAEVGRTVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Allofrancisella inopinata TaxID=1085647 RepID=A0A4R7LIH7_9GAMM ---EISNQITKLETQYGGKIGVYLIDYNDKSNF-GYNEKFHFPICSVYKFLVVGAVLKESM -VTPNLLNEKIKINENDIIGYTPITSKNIDKKLTITELSKATM-LSDNTAANLLIKKLGGL -KNLNKFIQSLGDRDTIITADEPAINNINLRDNLNKTSPQIIAKDLNKVAFKKILNKKNQS -LFKKWLQENNTGKDRIAFNIPKEWKIGDKTGTCEYGTTNDVAIIWPKNKKPIIIGIFYTQ -VDKNAKANDIVIQKITKILLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Asaia bogorensis TaxID=91915 RepID=UPI000EFA4A4E ----------RYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD -RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG -GTPDETQFRRVFHDIGALA---- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia ambifaria TaxID=152480 RepID=UPI0005BBC6BA ---AAQAELAALEKASNGRLGIAVLDTSNGTRI-AHHARERFPVCGTYAVVAAAAILARGS -LDASLLPRRILYRRYEVVAGSPVTESHVDTGMTIAQLCAAMLQSGDKGAGNLLMRVLGGP -QAVTSFAHESGDTVFRLDRWEPELNLAAPGDERDTSTPVAMVDLLQQLLLGDTLREPQRA -QLTEWMNGGTRGATGIAAGVPPGWRVADKAGTGGY------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI00135F4FED ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. Root670 TaxID=1736583 RepID=UPI000715D47E --dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP -QVVTKMLRDGGIQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA -LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAKEREAALADVARLAVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Larkinella terrae TaxID=2025311 RepID=UPI0012AD8C6E --qRLNQELERIAKLAKGKVGVCAVHLESGKQI-SLNLQERFPMASTVKVAIAVELFNKIE -KGELSLRTMVDLKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDMLLRLVGGA -EPVRARLKALGIEGMSVDRTIIQLIAKLEQDPRDTSTPAAMVNLLTQIYQAKALKPENRD -LLLAVMERCRGGLARIKGFLPPETVVAHKTGSLNSSATDDVGIITLPGDGHIAIAVFITS -SAQPLAEREQTIAHLSRTIYDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Labrenzia aggregata (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614) TaxID=384765 RepID=A0NUD0_LABAI ---SVGAAIEQIASGLAGRIGFAAQEIGGDEVI-AFNGDETFAMASTYKVAIATTVLDRVD -RGELSLDQLVEVPLDMFVTVNALAETFPHPGLSVANLIEVMITESDNTATDVSMGLAGGA -AAVTENLRRLGITDFRVDRTTREILMDFEADPRDHATPLAMLQLLLAIDGGTAMSPESRE -FLLGVMSRTRTGAERIKGLLPKGTPVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVYTNS -SETPVSDRDRAIAEIARMVFDHf ->[subseq from] Beta-lactamase n=2 Tax=Vibrio mediterranei TaxID=689 RepID=A6CVT7_9VIBR -------------------------------------------MMSTFKTLACAKMLHDAD -SGELDKNALAPITSDKLIPWSPVTEKMVGSSITVSKACEATMETSDNTAANIVLHSIGGP -QGLTEFLRLNQDDVTRLDRIEPELNQALSGDKRDTTTPNAMNTTLHRLLFEGALNQGSKN -QLMAWMQGNTVSDSLLRSVLPQGWSIADRSGAGANGSRGFNGAIWADNRKPLVISIYLTQ -TDLSMSERNQIINEIGGLIFQTy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=A0A1E5TQ52_9STAP -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNMANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGAPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147ILI6_9SPHN ------VRLRAIERAAGGRLGAFVLDTGSERSF-GWRADERFCHCSTFKLSLAAMALREID -AGRLDPMETLGFSQTDIVAYSPVVEQNLDKGLPILALAKAVQITSDNAAANVLMRRLGGP -DALTRFWREIGDNVSRIDGYEPSINVIPPGTIENSTTPRAMAKTVRRIVLGDVLGKASRD -RLRGWMAATQSGSKRIRAGLPAGWRGLDKTGTGMGNKTNDLAVLLPPGRSPLIVTGYFEN -PSFSED----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium barkeri TaxID=33917 RepID=UPI000377090E -----ADELAALEQEYDATVGVMAVDTGTGESV-SYGEDRRFGFASTIKAFAAAVFLQSVP ---GAARDEMVHWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLIVDRIGGS -AALDDALAELGDATTEVVNDEPTLNTIEPGSTDDTTTAAAFTASLTRILDGSTLSAADAA -LLVDWMSDNRTGDTLIRSGAPAGWTVADKSGGAGP-IRNDIAVVTRPGQDPIIITVLTSR -NDPHADFDDTLVASAASITL--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI0008FD0809 -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKAIASGVLLNNHS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KAFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQISDGNLD -LLKQVMIENETGDSLIKAGVSDNYIVGDKSGQGTYATRNDLAFIYPDKHNPIILAIYTKQ -DDKDGQPDDKVIADAAEEAI--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEB3_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLHKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTIWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. XS-30 TaxID=2604421 RepID=A0A5B9WJP2_9BACT --dSLRSEIAAIAARSGGTIGAGIMNLDTRDTL-FFQNDPVYPMQSVFKFPIAMAILHQVD -EGKLKLDQKIYIDKKWMVPWSPLRDAFPDGNQTLAQLLEYMVSQSDNIACDFLIDLAGGE -AVINDYVHGLGVKEIAIVASEAKMATAWDVQFTNFCAPSAMVQLLDILNKGTALSKTSND -FLWDIMLKTSTGPKRLKGLLPEGVQVAHKTGTSGTRATNDAGIILLPNGQKLAVVVYVMN -AKSDEATREATIAQIAKAAFD-- ->[subseq from] Beta-lactamase n=1 Tax=Ferrimonas sp. IMCC35001 TaxID=2569538 RepID=A0A4U1B8Y6_9GAMM ----VGAAIEQVATKLAGRIGFAAQEIGGKDII-AFNGDETFAMASTYKVAIAAAVLDRVD -RGELRLDQMVNVTLDMMMIGDAALNTHPGLQLSIANLIEVMITESDNTATDISMGLAGGP -AAVTKYLRRLGISDFRVDRTTGEIIGDFEADPRDQATPHAMLKLLLAIDSGTAVSPKSRD -FLLGVMSRTRTGASRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAVAVFTKS -SATPEPDRDRAIAEISRSLFDYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A448LJH9_9FLAO --sSLEQRISAITKSKQATVGVSVLGFENQFKY-SQNGEKKLAMMSVFKFHVACAALDLVD -KGKLSLDQKIFIKKSELYNWSPYKEKHPEGNATLSEIIYYTVALSDNNLCDILIELVGGT -QAVQKFMNSKGVKDFQIKYTERGMANGWDSLFENYTTANSTVQLLKKFYDGKLLSKKSTD -YLMKIMLGTKTGTNKIIEQLPKGTPIAHKTGSSGKKAENDMGIITLPNGKHYAIAVYVSN -SKESEAENCKIISDISKAVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas aveniformis TaxID=370977 RepID=UPI000688FC59 --------------EVGGRIGVQAVR--NGRAT-SWRAHERFTYCSTFKLFLAAATLERVQ -AGDEQLDRPVAMTAADMVSHAPVTGQAVGGTLTIQALCQATVEVSDNPAANILIREMGGL -TAWRDWYRRIGDTVTNVDRLEPELNGV--GDARDTTTPGQFVANLQTLFADDVLSSMSRS -LLMSWLFASPSGPNRLRAGVPVGWEVAHKTGTSSRGPVNDIGLLIPPGGHPIHIAVFWQG -REDDFSLGEAAIAEATRRVVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0013663FF8 ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase n=2 Tax=Francisella tularensis TaxID=263 RepID=A0A0B3VEE7_FRATU ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNHIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE440B6 --dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMRELGGP -QVVTKMLRDGGIQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA -LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAKEREAALADVARLAVS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4U2_ECOLX ------------------------------------------------------------- -----------XFKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQ--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Mucilaginibacter paludis DSM 18603 TaxID=714943 RepID=H1Y9U6_9SPHI ---ALHAKIDSIARDARGTVGFAMLNIESRDTL-SYHGNMHLPMQSVMKFPIAITVLHDID -EGQFTLNQLIHIDKSDLPKYSPLRDKYPEGNISISELLSYMVSLSDNNACDILLKTLGGP -EVVDQYMHSFGIKQIAVKASEFQMAQGWDVQFTNWVEPKTMVRLLDIATKPNFLSKASHD -YLWKIMEATSTGPNQIKDLLPVGTIVAHKTGRSGTNATNDIGLITLPNGKHLAIAIMITN -STADLTTRESVIARIAKAAYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga TaxID=79328 RepID=UPI000DBA38D8 --qTLRLQIAGIAGNISGKVGVYAEILETKDTV-SFNRDQHFPMQSVYKFPIAMAMLHQVD -QHKFRLDQPIHVTKDDLIGVSPVRDQHPEGNMPLGELIDYNIRASDGSACDVLLRLLGGT -AKANAYVHSLGVKQLAISTTEKVQVPSEMIQYKNWSTPMAMTQLLKIFYQEPVLSDSSKN -YLMHLMVTSRPGAKRLKGLLPAGTVVAHKTGTSWTRATNDVGIITLPNGHHLAITVFVSD -AKASEEEREGTIAKIAKAAYDHw ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 8AT TaxID=2653134 RepID=A0A653T598_9FLAO ----LAQKVDSIVKGKKATVGVSVLGFEDGFKY-NKNADTKLPMLSVFKFHIAAAVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT -QVVQKFMDSKGVKDFQIKNNEEQMHKGAKYLYENYTTANSLSQLYKKFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDDVNCKMISDISKAVWDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Variovorax sp. s2p11 TaxID=1367567 RepID=A0A0B5E9G5_9BURK -----------------------KLDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T1V8_9BACT ----LRNKIEQILSDKNAVVGVSIIGNNGKDTL-SLNGDKRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIQISEDELLPWSPLRDENPNGGFTIEKLIQYTVSHSDNTACDVLIRLIGTP -KSVEEYIKKSGINDIQITFNEEDMQAKWENMFQNWTTPKAASETLKLFYENNLLSKNSYN -FFWKTNKETTTGKNRIRGQLPNETIVAHKTGWSGTAAVNNIGIVFLPNGQYFIISVFVSE -SKENFDMNEKIIAEIAKATYDFy ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. FH2 TaxID=1674291 RepID=A0A0J7ISR5_9FLAO ---ALEKKISNIIKDKKATVGVSVLDFENNFKY-NKNGEKKLPMQSVFKFHIAAAVLDFVD -KGRLSLDQKILLNKTNLLEWSPLRDKYPNGGIPLSEVIENTVAMSDNNGCDILLKLIGGT -QTVQKFMDSKGVTGFQIKFNEEAMHKDWNVQYENYSTTNSAVQVLKKFYAGKLLSKKSTD -YLLKIMLGTKTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGQHYAIAVFVSN -STETDAINCKMISDISKSVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WSW2_9BACT ---QFRTEIEQIAQEAQGRVGVAATLLETGESV-GVHENEQYPMQSVYKLPIGMAVLHQVD -QGKLALTQLVHVSQSDYISHSPIRDKFPQGAITLAELLRYAVSESDGSASDVLLRVVGGP -DVVMNYLQTLGVTGVMVLNTEREIGSDNAVQYRNWAKPDQLVALLKAVQAGKGLSITSHA -WLLHLLIDTQTGLQRLKGLLPAGTPVAHKTGTSWTAATNDVGILKLPNGRHIAIAVLVSD -AKADAKTREAVIARIAKVAWDYw ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IJA1_9BACT --qRLQQELERMARLAKGKVGVCALHLESGREI-RMNANDRFPMASTMKVAVAVELLRKIE -KGELSYLTMTELKPSDLHPGSGTLETLFAKPLSLQNLMELMMVISDNSATDVLIRLAGGT -GAVQNRLKTLGIKGMSVDRTIIQLIATFDKDPRDTATPQAMVELLTQIYQAKAVSAASRD -TLLAIMERCRGGQGRLKGYLPPETVVAHKTGTMGASATDDVGIITLPGNGHIVIAVMVGA -SQAPSELREQTIAQISRSVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. 209 TaxID=1955701 RepID=UPI00098D1EC1 --qRMERELERIARLGGGQVGVQAIHLESGQQI-SYNPQLKFPMASTVKVAIAVQLLQRIE -RGELSLTTMVDLKPSDLHPGSGTLTALFNKPLSVQNLLELMMVISDNSATDILLRLAGGP -EAVRNCLKSLNVQGMSVDRSIIELLAAFGTDPRDTSTPAAMVDLLAKIYQGKALKPESRD -VLLGVMERCRSGEARLRGFLPPNTVLAHKTGSLGATATDDVGYITLPDDGHIAIAVFIGP -STQPTAEREQTIAHMARAVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=UPI0012F7CC22 ---RLRTEIEQLAQAAQGRVGVTATVLETGASV-NLNGDQQFPMQSVYKLPIGMAVLQQVD -QGKLALSQTVHVTPDEYISHSPLRDKYPTGAVSVAELLRYAVSESDGSASDVLLRLLGGA -KTVMASLKKLDITGIIVANTEKEIGSDNAVQYRNWATPTEVVALLRAVENGRNLSASSRT -LLLHLLTETETGLHRLKGLLPAGTVVAHKTGTSWTAATNDVGLITLPSGKHIAIAVFVSD -SKADQVIRERVIAQIAQVVWNHw ->[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. CACIAM 03H1 TaxID=2003315 RepID=A0A2Z2P1W3_9SPHN ----LAAELRIIEAAGDGTLGVEIHDTATGRSV-GINQDKRFGHASSFKFSLAALLLQRHA -AGAIDADRRVTWSEADMMHHAPFTRERIATGATLRELARATQITSDNPAANILLRELGGP -AALTAFWRSLGDEVSRLDRHEPEMNLVPTSEFRDTTTPAAMARTVAKIVYGDVLPEPQRA -ELKGWMIETDTGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGAPITFACYFRA -RQGMQPIGEQTLARVGRII---- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Novosphingobium TaxID=2644732 RepID=UPI00135B1F68 ---DAVDALRAIEARAGGRLGAYILDPARGSGV-GWRENERFAHCSSFKMSLAAMVLAGAE -RGEIDLDEVLRWSAQDLLSHSPVTSGAVDGGLPVKALAHATLVTSDNTAANVLLRRFGGP -VQLTHFWRSLGDTVSRLDRYEPELNQIPAGSEFDTTTPAAMAATVARLLLGDRLSPQGRG -TLKSWMIEVETGSDRLRSGFPADWISGDKTGTGGQQTYVDLAFGGPAKATPLIVACYLQT -ARDTDPLALAAMAEVGR------ ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NS46_9BACT ---RLRTEIEQLAQAAQGRVGVTATVLETGASV-NLNGDQQFPMQSVYKLPIGMAVLQQVD -QGKLALSQTVHVTPDEYISHSPLRDKYPTGAVSVAELLRYAVSESDGSASDVLLRLLGGA -KTVMASLKKLDITGIIVANTEKEIGSDNAVQYRNWATPTEVVALLRAVENGRNLSASSRT -LLLHLLTETETGLHRLKGLLPAGTVVAHKTGTSWTAATNDVGLITLPSGKHIAIAVFVSD -SKADQVIRERVIAQIAQVVWNHw ->[subseq from] Beta-lactamase class A n=2 Tax=Bosea sp. AK1 TaxID=2587160 RepID=A0A542B4Y7_9BRAD --dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP -QVVTKMLRDGGVQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA -LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAKEREAALADVARLAVS-- ->[subseq from] Uncharacterized protein n=1 Tax=Microbacterium sp. SZ1 TaxID=1849736 RepID=A0A2A4E5F2_9MICO ------PQIRAIEADFEVAVGAVAIR-DDGRIV-DHDGDARMPYASTMKVFMAAALLATAS -PEERGTNVRWTPSQIDAAGYSPVTSEHLDDGLSLDALAEAAVRDSDNTAANLVMESLDGP -AAVQDFLRARGDTTTVVTAYEPELNVVVPGSDDNTSTPSALATSLKSLFDGDSLDPRSRD -TLLDWMSGNASGDALIRAAAPSGWIVADKSGGAG-GVRNDVAVVTTGSGERIYIAILTAK -TDPDAAYDDEVVEQVARVMLAEf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter sp. eg TaxID=2201271 RepID=UPI000EB1E130 --tTLQHKLDSIVKSKRADVGFSALFLPDQKNI-SVNGNKHYPMQSVYKFHLALTVLNLVD -NGKFSLQQKIRIKKSDLLAWSPLRDKYPEGNLPLAEILKYTVSQSDNNGCDILFRLIGGP -KSANDFIKKQGIKDINIVATEEEMHKDDQVQFSNWTTPNAANELLRKFLAGKILRKTTQN -FLMKIMEETSTGPGKIKGLLPQGTRVAHKTGSSGTAASNDIGIVSLPGGKKIIISAFVSM -SKENEAENDKIIAELTKAVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A515A0J9_9BACT --nSLRNQLEQIARTAQGRVGVTATVLETSETV-TLNGDQQFPMQSVYKMPIGMAVLQQVD -QTKLTLEQVVHVTPSEYVSHSPLRDKYPTGAVSVAELLRYAVSESDGSASDVLLRVLGGP -KVVMNYLHTLGINGIIVANTEKEIGSDNAVQYRNWAKPNEAVILLRAVQEGKGLSASSRT -LLLRLLTETETGLHRLKGLLPAGTIVAHKTGTSWTAATNDVGLITLPNGHHTAIAVFVSD -SKADQTTREGVIAKVAQAVWNYw ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. SZ1 TaxID=1849736 RepID=UPI000BBC5EBF ------PQIRAIEADFEVAVGAVAIR-DDGRIV-DHDGDARMPYASTMKVFMAAALLATAS -PEERGTNVRWTPSQIDAAGYSPVTSEHLDDGLSLDALAEAAVRDSDNTAANLVMESLDGP -AAVQDFLRARGDTTTVVTAYEPELNVVVPGSDDNTSTPSALATSLKSLFDGDSLDPRSRD -TLLDWMSGNASGDALIRAAAPSGWIVADKSGGAG-GVRNDVAVVTTGSGERIYIAILTAK -TDPDAAYDDEVVEQVARVMLAEf ->[subseq from] class A beta-lactamase n=1 Tax=Asaia prunellae TaxID=610245 RepID=UPI0011DCDA67 ----LAEIARHYEQKSGGRIGVHLFCPETGSAL-SWRGKERFLMCSSFKASLAACVLARCD -GDDDDLTHRLPFIDSDFRTWAPVAQKNRDAGLSLAALCAAAVTMSDNVCTNMLLRHIGGP -STLTKFWRESGDDVTRLDAYEPELNRPSADPQANTTSPVAMARTLHRLIHGTLLHPNSAA -LLRGWMTKCTTGTHRLRAGFPSDWVVGDKTGSNGKDIAADIAFASPESSKSVIIAAYTSG -GRPNETQFRKIFRDIGAL----- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI001412548B ---ALRKNIQEILNTSKAKVGVAVLGLEDRYSL-TFYPKIHFPMQSTYKFPVALAILDRVD -KGKLKLDQKIHVSKSELHPWSPMREKYPEGNLPLSELLAFMVSQSDNNACDILFAIAGGP -KKVDQYVKALGVKQIAIAATEYEMHQGWEVQYTNWCEPWAMMQLLDLFHKRKLLKKPTHD -FLWKTMVETTTGPKKIKGLLPKGTLVAHKTGSSGTAASHDVGIVTLPDGKHFGIVVLVGD -SKETEEFREALVAKISKATWDYy ->[subseq from] Beta-lactamase n=1 Tax=Dyadobacter jejuensis TaxID=1082580 RepID=A0A316AA41_9BACT --qDLREAISTIVEQAEGKVGVGVLNVQRSEPV-YWNENHRFPMQSVFKFPLALAVLDRVD -KGELDLQQVVPITRADLPPWSPIRDKYPSGDLTVSELLQYTVSQSDNNGCDLLFRLLGGP -ARVDAYIKKWVPEGIAIVADEAKMATAWEVQFGNYATPVAMSRLFQQFYAGQILSAGSTA -YLKQILLETNTCTACMKGLLPEGARVAHKTGRSATAATNDAGVLLLPNGQEVVVVVFVGD -SPADDRTREGIIAQVSRAVWDHy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=UPI0013DFFDCF ---TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID -RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP -AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK -ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS -DTKGVDTQERVIAEIARTAYDHy ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium greenlandense TaxID=345663 RepID=A0A101CI81_9FLAO ----LEQKINSITKDKNATVGISVLGFENGFRF-NKNSDKKLPMQSVFKFHIAAAVLDYVE -KGKLSLDQKIALNKSNLHEWSPLREKYPNGNVTLGEILEFTVAKSDNNGCDIMLKLLGGT -KTVQNFMNSNGVKNFQIKFNEEEMHKDWNVQYENYSTTQSAMDVLKKFYDGKLLSKKQTD -YLMQVMLSTSTGMNKIVEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIALFVSN -STESDATNCKMISDISKAVWDYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XXM3_9BACT ---TLESRLAALAAEAGGVAGVAILHVESGQRA-SLRGGERFCMASVYKLPIAIALLRSVD -RGRIALDQKVTYGARDLRPHSAIVDRAAGGSATVRELVEAMLIESDNTASDLVMGLLGGP -AAVTAELRAAGLGGIDVSRPEGQIALRFASDPRDTATPDAMATLLGRLQKGELLQPPRTA -LVLDLMTRATTGPDRLKGLLPKGTVVAHKTGTGGNSCSNDVGLLTLPDGSHLAVAAFVRT -SPRPLAARERAIARIGRAAYDRw ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A3A0H0Y9_STAGA ------KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS ---PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCISEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMQKGNLQ -FLKELMIENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKPNDEVIAKTAEIAIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=UPI000D1DE64A ------KSIKDLEATYDTTIGVYGINTQDGKQI-EHRANERFAFASTYKAIASGILLNQLS ---PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCVSEPQRLEPNLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ -FLKELMIENETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKPNDEVIAKTAEIAIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1F4002 -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHHSDERFGYASTFKAIASGVLLNNYT ---EREINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKTALQHLGDHVSDPQRLEPKLNDYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLK -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter alluvionis TaxID=475253 RepID=A0A497Y8Y4_9SPHI --qDLKKAIETIAGKHAAKIGFAVADLQNGDTI-GFNGIAHYPMQSVYKFHLALAVLKQVD -EGKLTLDQQILVKAKDLLPWSPLRDKYPQGNIPLAEILGYTVSQSDNNGCDILFRLVGGP -AKVNQFIHGIGLKDVAIVATEEEMHLDEKVQFKNWSTSFSAVQLLKMFYDKKILSKSSGD -FLWDIMVKTVSGPNKIKGLLPKGTIVAHKTGSSGTTASNDIGIVALPNGKHFAIAVFVSM -TKEEEKVTDQIIAECSKATWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. 1.5R TaxID=1916917 RepID=UPI0011A1372C -------QIRAIEAEFAVTVGVVAIR-DDGRIV-EHDGDVRMPYASTVKVFIAAALLATAS ---PEERGTNVRWTASQIVAYSPVTSEHLGDGLSLDALAEAAVRDSDNTAANLVMESLGGP -AAVQDFLRARGDTTTVVTAYEPELNVVVPGGDDSTSTASALATSLKSLFDGDSPDTGSRE -TLLDWMSGNATGEALIRAAAPAGWIVADKSGGAG-GVRNDVAVVTTGSGERIYIAILTAK -TDPDAAYDDEVVEQVARIVLAEf ->[subseq from] Serine hydrolase n=1 Tax=Desulfobacteraceae bacterium TaxID=2049433 RepID=A0A3A4SL68_9DELT --kDVSQKIEKLAEGLVGRIGVAAQEIGGDQVI-AVNGDETFAMASTYKVAIATTVLDRVD -KGELSLDQLVEVPQDMYVTVIALAETHPGVKLSVANLIEVMITDSDNTATDVCMGLAGGA -AAVTKNLRRLGITDFRVDRTTREILMDFEADPRDHATPLAMLKLLLAIDGGTAMSAESSK -FLLGVMSRTRTGAGRIKGLLPKGASVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVFTNS -SKTSVADRDRAIAEVSRTLYDFy ->[subseq from] Class A extended-spectrum beta-lactamase PER-14 n=1 Tax=Raoultella ornithinolytica TaxID=54291 RepID=A0A650A8W0_RAOOR ----LKEQIETIVTGKKATVGVAVWGPDDLEPL-LLNPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQSVTVNRAAVLQWSPMMKDHQGDEVAVQQLLQYSVSHTDNVACDLLFELVGGP -QALHAYIQSLGVKEAAVVANEAQMHADDQVQYQNWTSMKAAAQVLQKFEQKKQLSETSQA -LLWKWMVETTTGPQRLKGLLPAGTIVAHKTGTSGTAATNDAGVIMLPDGRPLLVAVFVKD -SAESERTNEAIIAQVAQAAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Solibacter usitatus (strain Ellin6076) TaxID=234267 RepID=Q025P5_SOLUE ----LSTHFADLARPAAGKVGASVLVIETGERA-GFHARDPFPMQSVYKFPIAMATLHLVD -TGKLKLDQPVPIAKAELAPHSPIRDQHPEGALSLREVIRFAVAESDGTASDVLLRLSGGP -SAVTAYLRGLGINGVIVATSELEMSRGPMVQYRNWATPDSMVDLLRAFHAGRGLSPAART -LLEDFMAQSTPGPKRLKGLLPPGTRVAHKTGTSGTRATNDVGIVTLPNGRHLAIAVFVSD -STASLDLREEAIAKIARAAWDAf ->[subseq from] Uncharacterized protein n=1 Tax=Agromyces sp. Leaf222 TaxID=1735688 RepID=A0A0Q4HDD8_9MICO -heRMSRDLRELERAASVTIGVHAVDHRAGRPVfRYRGADLFPMCSLFKVLAAAALVRDRG -YDEAYWTTPIPFAKADVVRDSIVLEALRPRRATPGQLADAALRYSDNTAGNLLLRELGGP -SAITAFAASLGAKRTRLDRWEPELNDAVPGDVRDTTTPDDIALLSTALLLDDAAGVLASS -RLREWMLRNTTSGARMRAGLAAPYELADKTGGGEYGVVNDAGVLWRAGRDPLTLVILTRT -DRPDATRNNEVVAEATRIVVG-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A075M8X1_ECOLX ------------------------------------------------------------- --------QRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYF-- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2KX69_9CYAN -----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD -EGKISLKQLVTITRQEFAPWSPIIKEVKGDRIPLRNVLEGSVGISDNTAADALVRLVGGT -KQVNAILGKLQIRNIRVDRLEQQLQPKYLTDPRDTATPEAMVDLLAKLNSNQLLSENSTA -LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGANTATNDVGIATSPDGKRVAIAVFIAG -SKAPLEEREKVMSNIASRVVQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium xixisoli TaxID=1476462 RepID=A0A4R8I377_9FLAO ---ELRKELNQIISTKNATVGISLKGIENKDTL-SINGNMNMPMMSVFKFHIALAVLNEVD -RGKLALNQKIFIKKEDLKEWSPIREEFPNGNLTLDQLLRYTVSHSDNNGCDILLELIGGT -ETVQKFINKNGIKDFTIKMNEDQMRT-WENLYINTTTPIATTKLLEKFYNGKVLKKTTTK -YLYQIMVECSRGTTWMKAGLPAGTELAHRTGISGTNSMNDIGIIKLPNGKHFILSIYLKN -ITESREDTEKIIADITRATWNYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. K2R01-6 TaxID=2320861 RepID=A0A418WQC1_9SPHN ---AIEQQVTRLGQGSGGVVGVAAWRLDKGPRV-LVNADQAFPMASTFKVAVAAKIFDRVD -KGELRLEQMLDVPSDMIVPSEVIADRLIHPGLSIYNLLELMLTQSDNTATDVLTKAAGGP -AVVTAWLRGQGVTGQRVDRDTAGLLRVFDEDPRDTSTPTAMATLLTRIFSGKALSAQSTK -ALIGIMERCRTGGARLRGKLPPGTVVANKTGTIG-GTVNDTGVITLPGDGQIAIAVYVKK -SAAPMADRERAIAEIARSVHDFy ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sancti TaxID=1004 RepID=A0A1K1PIW1_9BACT ---ALRKTIDSIATHSKSRIGVAALLLETGDTL-TYKGNDHYPMQSVYKFPISFAILHQVD -LGEYKLDQKITITNDDILPHSPIREAHPHGGMTIREISRLNIQESDGTACDVLLRLLGGT -KKTDDYIKSLGVKGINIATTEKEQQTNDTIQYRNWATPIAITQLYKVYFQSNILSKSSYD -VLWKDMTESHPGPKRIKGQLPAGTIVAHKTGTSGTAATNDTGIIILPNGKHLILTVFVSD -SKGSEAEREGWIAQISKAVYDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf9 TaxID=1735674 RepID=A0A0Q4CPI1_9SPHN -----ATSFANVEQLHGGRLGIFALDTQTGRSL-AYRADERFKLMSSFKGLLSAMILLDVA -KGRGSLDAPVRYQPSDLIPASPVTQANVARGMSVGELCEAIMYRSDNTAANLLMRRAGGP -ARLTAFLRSIGDTVSRIDHYEGDLTGH--PLPADSTSPRAVTKAVRQIMLGTILPSFAQR -QWEGWMAGNVLGRTRLRAGFPANWVSGDRSGTGD-GICNDFAFARRPAAAPLLLSVYYAA -PGSELADQEAVLRKIARLVVQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium EhC05 TaxID=1849171 RepID=A0A1B6Z548_9SPHN ------SEIAEIEQNIGGRLGVGLIDGEGALIL-AHRGDERFALCSTFKAALASVLFAAHA -AGTVDMFAKFALKPADRVPYMPFVDKKLAAKVSLHQLAGAAVMTSDNAAANLILKATGGP -AEFTRFVRAQGDDVTRLDRIEPELNENAIGDPRDTTSPVAMARLIKKLALDDAALDIDKL -TLQNWMKASKTGASRIRAGLPKGWPVGNKTGTAAGGARNDIAIIWPAAAKPVTLTVYVDR -PMAPPEEVDAAMADVARIAA--- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium gregarium TaxID=456299 RepID=UPI0003F656DD ----LAEKINVIVKGKNATAGISVLNFENGFSY-HQNADKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKVTLDASNLMEWSPLRDKYSGKNVALSEILEYTVAKSDNNGCDILLKLLGGT -ETVQKFMDSKGVKGFRIKYNEAEMHKDWNAQYENYTTAKSAVDVLKKFYDGKLLSKKSTD -YLMKVMFSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAIITLPDGRHYAIAVLVSN -STETDAVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TET7_9BACT ---SLRKKIQQIVSTKNAIVGVSIIGNDEKDTV-SLNGERHYPLQSVFKFHIALAVLSQID -KGKFSLDQKVEIQKKDLLPWSPLREENPNGGFPISKLIQYTVSQSDNVGCDALLRLLGGP -IVVEEYLKKNNIKDISIKLNEEKIQANWDLQFQNWTTPKAANEVLSKFYYNKLLSKKSYD -LIWKTMKGTETGKARLKGQLPKGTIVAHKTGSSGTAAVNDIGIIFLPNGKHFFISVFVTN -SKENEETNEKIIADIAKVAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=UPI000837ED51 ----VSTVIRNLEQRFDARVGVSAFDTETGATM-SYRGSERFGFASTLKAFAAAEFLRQTS ---TEDRDELVRWTRSDIDRYSPVTTENLDTGLTAAELAEAAVRESDNTALNLVLDRIGGP -EGLDDALELLGDATTEVVNYEPELNTITSGSIDDTTTADAFTESMTALQQTSYSTSSNRS -ILLDWMSGNKTGDPLVRAGAPAGWVVADKSGGAGP-IRNDIAVVTPPERSAVVITILTEK -NDPAAQFDNELVSETAAVVLH-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium piperi TaxID=558152 RepID=A0A086AQQ0_9FLAO -htTLEQKIDSIINDKKATVGVSVLGIEDPLNY-NKNGEKKLPMQSVFKFHIAAAVLNLVD -MGKLSLDQKILVKKSDLLDWSPLREKYPNGNIPLSEIIDFTVAQSDNNGCDILLRLIDGT -NTVQKFMDTKGIKNFQIRFSEEEMHKDWNAQYQNYSSTNSIVQVLKKFYEGQLLSKKSTD -YLMQVMLGTKTGTNKLIEQLPKNTPVAHKTGSSGTGAENDMGIVTLPNGKHYAIAVFVSN -STEAEAVNCKIISDVSKAVWD-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. YR221 TaxID=1500293 RepID=A0A1W1YZN5_9FLAO ----LGQKINAVTQGKNATVGVSVLDFDNKFRY-SKYGDQKFPMQSVFKFHIAAAILNYVD -QGKLSLNQKVLLDSSNLLEWSPLRDKYPNGNVPLSEILELTVARSDNNGCDIMLKLLGGP -QTVQKFMDSKGIKGFQIKYNEAEMHQNWNVQYENYSTPNSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN -SMETDAVNCKMISDISKEVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. RP-1-16 TaxID=2572196 RepID=A0A4V6WPQ1_9SPHI ---SLQEKLAQIIKGKKADVGVSVFFLGDRRSI-SVNGDQHYPMQSVYKFHLALAVLDQVD -KGKMALHQKIFVKKSDLLPWSPLREKYPNGNLPLSEIIRITISESDNNGCDILFRLVGGP -NKVHKYIVKLGIKDCAIAATEEEMHKDDKVQFTNWTTPKAANLLLEKFWNGQVLKKNTSA -FLMKAMEETVSGPNKIKGLLPSGTIVAHKTGYSGTAATNDIGIVRLPNGKRILISVFVSM -SKETEKVNDLIIAELARAAWD-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A1L6J8L2_9SPHN ---TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID -RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP -AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK -ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS -DTKGVDTQERVIAEIARTAYDHy ->[subseq from] Beta-lactamase n=1 Tax=Asaia platycodi SF2.1 TaxID=1382230 RepID=A0A060QHF4_9PROT --hALSDIATRYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD -RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAFEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG -GTPDETQFCRVFHDIGAL----- ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia ATCC 25015 TaxID=539329 RepID=C6YW16_9GAMM ----ISNHLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL -NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNSKIIREVTKILLD-- ->[subseq from] Class A beta-lactamase n=2 Tax=Cryobacterium flavum TaxID=1424659 RepID=A0A4R8UZZ5_9MICO ---AFNRRIEDLEMQSGVTIAVTAVNLGTNRRV-QHRSTDLFPMCSLFKVIAVGALVSERG -YDEQYWNTPIPFTAADIVVNSPVASKLTTLTMTPDEMADAALRFSDNTAGNLLLREIGGP -KTIARVVGSFGATATRLDRIEPELNEGLPDDPRDTTTADDMVAVLRALLVDGGAGQLARS -KLHDWMLRNSTSSTRARAGLTGSYELADKTGAGGYGIVNDAGILWPDDTDPIALCILTRT -NDPNAKGNNEVIADTTRLLVS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mucilaginibacter xinganensis TaxID=1234841 RepID=A0A223P0F4_9SPHI ---GLRQQISDIIKPAKGIVGVSILNLESRDTL-SVNGDARLVLHSVMKFPIALTMLHWVD -SGKLTLDKMIHIKKKDLPKYSPLRDKYPNGNVSVSDLLSYMVSLSDNDACDILLKLIDGP -KTVQDYMLRLGIRGIAVRATEADMASSWELQYTNWCKPKEATLLLDKFYKGEILAKNTTA -FLYKILTETSTGPHRIKGLLPAATVVAHKTGTSPTNATNDVGIIELPNGKHLAISVFVCN -STDNEATREAVIAKIAKAAFDYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=UPI0013DF6909 ---TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID -RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQTGGP -AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK -ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS -DTKGVDTQERVIAEIARTAYDHy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=J9V7T2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGLAMGDSQRA -QLVTWLKGHTNGA----------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium piscicola TaxID=551459 RepID=A0A1N7N125_9FLAO ----LDKKITTIVKDKKATVGISVLGFENGFKY-SKNGEKKLPMQSVFKFHIAAAVLDLVD -KGKLSLNQKIVLTKDNVLEWSPLRDKYPNGGVSLNEILELTVAKSDNNGCDIMLELLGGP -KTVQDFFDSKAVKNFQIKYNEAEMHKDWNAQYKNYTTMNAAVDVLKKFYDGKLLSEKSTD -YLMKVMLSTSTGKNKLIEQLPKNTSIARKTGASGTGAENEIAIVTLPNGKHYAIAVFISN -SMESDEVNCKMISDISKVVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Bosea robiniae TaxID=1036780 RepID=UPI000891C1B6 --dKLDKAIEGIEQQAEGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP -QVVTKMLRDGGVTGLSIDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA -LLTQIITETKVGADRIKAGLPAGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAKEREAALADVARLAVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=UPI000834FFA4 ---KLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID -KGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP -AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAVIQSGKALSASSTK -VLIDIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS -DTKGVDTQERVIAEIARTAYDHy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium taeanense TaxID=311334 RepID=A0A1G8NAC6_9FLAO ----LDKKISSIIQDKKSTIGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAATVLDYVD -KGKLSLDQKVLLDKSNLLEWSPLREKYPNGGIPLSEVLEYTVAKSDNNGCDILLKLLGGT -QTVQRFMDSKGLKGFQIKYNEAEMHKDWNNQYKNYSTASSATEVLKKFYDGKLLSKKSTD -YLMKVMFSTSTGKNKLIAQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYAIAVFVSK -STESDVVNCKMISDISKSVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000D1C34EE -----ANEFDKIEKDNNTTVGVYGINTENGKKV-QHNANERFAFASTFKSIASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKGGQPDDKVIADAAEEAI--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Haliea sp. TaxID=1932666 RepID=A0A519IZX4_9GAMM ---DFDATIRQIEADSGGRLGVAILDTQSLRLW-SHRAGERFPMCSTFKLLLAAQVLSRVD -QGREHLGREIAVQASDLVPYAPVTAPRVGGALTVAELCEAAVTLSDNVAANLLLRSAGGP -AALTAYARSLGDGLTRLDRIEPHLNEAAPGDLRDTTTPAAMLQTLQKIILGDALSPASRA -HITDWLRASKTGARS--------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011551F34 -------------------------------------------------------VLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARGDEVSRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAA------- ->[subseq from] class A beta-lactamase n=1 Tax=Microbacterium sp. G1 TaxID=2615184 RepID=UPI00124B3940 ----VADELAALEQEYDATVGVMAVDTGTGESV-SYGEDRRFGFASTIKAFAAAVFLQSVP ---GAARDEIVHWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLIVDRIGGS -AALDDALAELGDATTEVVNDEPTLNTIEPGSTDDTTTAAAFTASLTRILDGSTLSAADAA -LLVDWMSDNRTGDALIRSGAPAGWTVADKSGGAGP-IRNDIAVVTRPGQDPIIITVLTSR -NDPHADFDDTLVASAASITL--- ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. zg-578 TaxID=2663858 RepID=UPI0012B5EE91 -----DRRLAALEERYDARVGVSLLDTGDGAAY-SYRGDQRFGFASSVKVLVAAELLRRTG ---SAERAELVRWTQDDVDAYSPVTEAFVGRGLPLLRLAEAAVRESDNTATNLVLERLDGP -AGLTRGLRGRGDTTTVVADDEPGLNEVSPGSPANTTTPDAFVADLRALLGPEWLTDADRR -LLLGWMSGNPGGDPLIRAGAPAGWRVAQKSGGAGP-VRNDVAVLTPPDGAPVLLAVLTTR -LDPTAPYDDALVADAAEVAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf296 TaxID=1736327 RepID=UPI0009EB90EC ---AVDAALSALEAEYDARIGLVAVDSEDERTV-EHRADERFRFASSIKALAAGALLARTE ---PSDLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP -AGLQEALRALGDDVTRVDRVEPELNRVSPE-GLDTGTARSLAADLRTLLLGDPLDSADRA -QLRDWMSGNATGDALVRASAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER -TDPTLPYDDALVARAASVALE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Agromyces sp. CF514 TaxID=1881031 RepID=A0A1I6JI17_9MICO ----IARELAALERETSVTVGVVARTHGDRRAF-RYRADSVFPMCSLFKTLAAAALVRERG -YDEVYWSTPIPFA--DAVVDSPILGPKAPGRATPEEIADAALRYSDNTAGNLLLGELGGP -QAITAFAASLGATRTRLDRWEPDLNAAVPGDARDTTTPDDIAALYEALLLDDAAGVLAGA -RLREWMLRNTTSNARMRAGLTPPYELADKTGGGEYGVVNDAGVLWREGRAPVTLVILTRT -DRPDAVRNNEVVARATRIVI--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=Q8VT49_9FLAO ----LEQKINSIIKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIMLNQSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QVVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAADVLKKLYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISKEVWEYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unknown TaxID=N/A RepID=UPI0014385E6A ---SLNTDIKSLLDSKQATVGVSIWDQNANPIV-EINADNQLPMQSVFKFHLAVAVLHQVD -QGKWSLADKITITPDDLDNWSPIRKKYPTGALTLAQIIKYTVAVSDNVGCDVLIGMLGGP -KVLEQYLHQAGIKDVAIKYNEEMMQQVWQRQFDNWTTANGANQALSKLYDEQLLSATSHR -FLWDVMKSSKTGKNKIRAGVPEGTVVAHKTGYSGKHAHNDIGIVFLPNGSHYYISVLVSD -SRESSDDSQKIIADISQLAWMHf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomycetes bacterium Poly41 TaxID=2528016 RepID=A0A5C6E232_9BACT --kDVSQKIEKLSQGLVGRIGVAAQEIGGDQVI-AVNGDETFAMASTYKVAIATTVLDRVD -KGELRLDQLVEVPPDMYVTVIALAETFPHPGLSVANLIEVMITESDNTATDVCMELAGGA -AAVTKNLHRLGITDFRVDRTTRQILMDFEADPRDHATPLAMLQLLLAIDGGTAMSAESSK -FLLGVMSRTRTGADRIKGLLPKGTSVAHKTGTAG-GIANDVGYVTLPDGRRFAIAVFTNS -SKTPVADRDRAIAEVGRTLYDFy ->[subseq from] Beta-lactamase n=1 Tax=Dyadobacter sp. SG02 TaxID=1855291 RepID=A0A1H6W0L9_9BACT --aKLKSDIETISKQAQGIVGVGIMNLKTQETL-LINQDHKFPMQSTFKFPLAMAMLDLVD -KGKYKLDQKIHVTQSQLEKHSPMRDEYEGKDITVGELLSYSVSESDNNACDILFGLAGGT -KIVNDYIHSLGVKDIAIVATEKEMATGWNTQYDNFARPSAYLQLLEIVYLRKKFSKSSQE -FLWKIMVDGPTGLKRIKGELPKGTVVAHKTGTSGTAATNDVGIVKLPNGNDIAIVVFVSD -ATANLDTRERVIAQIAKAAWNYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CCH4-E10 TaxID=1768758 RepID=UPI00082E4F4D --sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD -QGKLSLDHKILLDKTNLLEWSPLRDKYQQGNVPLSEILEYTVAKSDNNGCDIMLKLLGGP -ETVQKFMNSKGVKGFQIKFNEADMHKDWNAQYQNYSTAASATEVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAVVTLPNGKHYAIAVFVSN -STETDAVNCKMISDISKSAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter steynii TaxID=430522 RepID=A0A1D7QMH8_9SPHI ----LQQKMDSIIHSKKADVGVSVLFLEDHKIV-SVNGDKHYPMQSVYKFHLALAVLNQVD -QGKLALDQKILVKKSDLLPWSPLRDQYPEGNLRLSEILKYTVSQSDNNGCDILFRLIGGT -KKAHQFIVKQGIKDISITGTEEEMHKDDQVQFRNWTTPKAANELLKKFWEGKVLKKPTAD -FLMKVMEETVTGTGKIKGLLPQGTVVAHKTGNSGTNASNDIGIVTLPNGKKMLISAFVSM -SKENDKEVDKIIAELSKAAYD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Rudanella lutea TaxID=451374 RepID=UPI0003721717 ----LRTEIQRIVAGKKAVVGVSIIANDGKDTL-SLNGDRRLPLQSVFKLHIGLAVLAQVD -KGRFTLDQTVEVRKDDLLPWSPLRDENPNGGFSIAKLIQYAVSQSDNVACDVLIRLLGSP -KAVETYIKENGVEEIAIRFAEKEMQAEWDNMFQNWTTPKAASKTLQTFYDGKRLSKRSYD -FIWQTLRETNTGVNRLKGRLPAGTVVAHKTGSSGTAATNDIGLLFLPNGEPVIISVFVAD -SQENEATNEKLIADIAKATYDFy ->[subseq from] Uncharacterized protein n=1 Tax=Pelomonas sp. Root1237 TaxID=1736434 RepID=A0A0Q6XEN8_9BURK -----AADFAALERRVQGRIGFFAIDTGSGRVM-AHRADERFATASTFKILLAARVAQGVE -AGRWGWNDAVPLRESERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDSP -AGLTTWLRQQGDAVTRLDRFETELNENAPGDPRDTSTPRAFARTLQHLLLGPGLKRANQA -RLWADLQASRTGLKRLRAGVPASWRVIDKTGSGARGAVNDVALVFPPGGSPWVVVAFQSD -SKASSDELSTVHADAMRGLVRAw ->[subseq from] Beta-lactamase class A n=2 Tax=Microcoleus sp. PCC 7113 TaxID=1173027 RepID=K9WDF5_9CYAN --tQLQEQLNNLDSSAQGDVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPLGIVVLKLVD -EGKLSLNQTVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP -EQVTANLERLNLRDIRVDRLEQQLQPRYLVDPRDTATPEGMIDLLALLQSRQLLSEDSTA -LLLKIMTDSPTGQKRLKAGLPQGWSIAHKTGTGEDVATNDVGLISSPSGRNIAIAVFIAG -SKAPLEQRESVMSAVAAAVVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A539DEI8_9PROT --------LELLEQKVGGRLGVFMLDTDTGLAQ-THRGKEPFGMCSTFKLPLAGVVLREAD -AGRLDLEERIAFTQADMVPHAPVTSQHLAQGMTVEALAETAQKTSDNVAANLLIKRLGGP -EGVTAKVREIYAHGFRLDRYETQMNFVPPGEVRDTATPEGMGLIVSNLIATRGLTPASRG -TLIQWMHDTRTGLKRIRAGLPREWPAGDKTGTADPNKVNDVAAIWPTTGGPVIVVAFYEA -PGGTRNQDQEVLAEVGKLA---- ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter sp. HI0063 TaxID=1822240 RepID=A0A165R6F5_9SPHN ---EIYARLAELAERAEGTLGASVLDPGSGAFA-SWNGDRRFPHCSSFKVSLAAMVLDLVA -RGQIDGKRLLHWSEADLMWVSPFTTRRLGQGATFLELARATQVTSDNTAANVLLRELGGP -EALTAWWRALGDGTSRLDRTEPALNRVLPGEVHDTTTPDAMARTMATILYGDALAPSVSE -RLASWMAKTETGSRRVRADLPDRWRAGDKTGTAMGSAYVDIGFVVPDGRGPLTFATYYMV -DADMDPQAEALLAEVGRTIAAVf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6S710_9SPHN ------AQLRTLERSAQGRLGAFVLDTATGRHF-GWRADERFCHCSTFKLSLAAMALRESD -AGRLDLAEPLAIGRTDVVAYSPVVEDNLAKGLPILILAQAVQITSDNAAANILLRRLGGP -DALTRFWRDIGDETSRLDGYEPAINVIPPGTQENSTTPRAMAMTVQSLVVGDVLRPASRD -LLRGWMAATQSGLDRIRAALPRNWQGFDKTGTGMGNKVNDLAVLVPPDGSPLIVTGYFEN -PSDVRPQDEAVLKRLGEIAV--- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A430G415_9SPHN ---TLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID -RGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQTGGP -AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAAIQSGKALSASSTK -ALIEIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS -DTKGVDTQERVIAEIARTAYDHy ->[subseq from] Beta-lactamase n=1 Tax=Rheinheimera sp. A13L TaxID=506534 RepID=F7NRS8_9GAMM ----LKEQIETIVTGKKATVGVAVWGPDDLEPL-LVNPFEKFPMQSVFKLHLALLVLHQVD -QGKLELSLSVAVKRAEVLQWAPMMKDYQGDEVTIEQLLQYSVSHSDNVACDLLFELIGGP -AALHAYIQFVGIAETDVVANEAQMHADDQVQYQNWTSMKAAARILKKFEQKELLSETSQA -LLWKWMVETTTGPERLKGLLPADAVVAHKTGTSGTAATNDIGVIMLPDGRPLLVAVFVKD -SAESNKTNEAIIAQVAQAAYQ-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A2M8WBT0_9SPHN ---KLESAFALLARQTDGTVGVAVQRIGGGPVY-TLNAGQTFPMASTFKIAVAGAVLARID -KGDFKLDTMVTVDPAVWVQSAGIAEQHPGVALSVHNLLELMLTRSDNTATDVMVTQAGGP -AAVTAWLRKVGVTSQRIDADTARLIYPFNNDPRDASTPEAMVQLLAVIQSGKALSASSTK -VLIDIMERCITGEKRLKGLLPQNTVVAHKTGTLMS-IANDVGIVTMPDGSKFAIAVFVKS -DTKGVDTQERVIAEIARTAYDHy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. URHD0057 TaxID=1380389 RepID=UPI00048FD646 --qALQSELSHLAKPAEGVVGIAAWRLDAGPRV-LVNADQGFPMASTFKVAVAGKILADVD -GGKLSLDQLVPVPHAMMVESEGLASTFRYDGVSVRNLLELMLTVSDNTATDVLTKLAGGP -TAVTAWVRSQGIEGLRVDRDTAGLIRKFDKDPKDTATPLAMGTLLQRIFTGKALSSASTK -LLTGIMERNTTGKARIRARLPEDTVVAEKTGTIG-GSVNNVGLVTLPDGGKVIMAIFIKE -SRQPFEVRERVIADVARALYDYf ->[subseq from] Beta-lactamase n=2 Tax=Phenylobacterium zucineum TaxID=284016 RepID=B4RHE4_PHEZH ---RLNEEMAELARRAPGALGVGLMNLESGEAF-TLAGDRRFPMQSVFKMLLGAAVLSEAD -AGRLPLDERHSLTEEQLSPYSPIAEAWPARRYTARELLTAAVSVSDNTAADVLMKRIGGP -GAVDAWLQARRIEEIRVDRYERQLQTAYLADPRDTATPRGMLEFLSRLNANELLSPMSTL -LLLQLMTDTPTGARRLKAGLPDGAILAHKTGTARTDAINDVGIFTLPDKRSYALAVFLAG -STLDRAAREAIFADAARIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus edaphicus TaxID=1955013 RepID=A0A2C6U8F1_9STAP --nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGY -GQVKTKLIDLGDTTTHPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD -FLLNLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK -DRKYGKPNDKIVSEVAEIVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas sp. S30B TaxID=2561925 RepID=A0A4Y9RCE2_9CAUL -------DLSALETRPGDRLGFAVHDLASGRRL-AWRGEERFVYCSTFKMYLAAATLLRVQ -AGEERLDRAIAITRADMINHAPTTEPAVGSTLTVEQLMKGTVELSDNPAANILIREMGGL -DALRAFYLGLGDDSTTVDRLEPEMNRL--DGDKDTIQPLQSAANIRRLLVDTPLNADSKA -RLMRWLIDTPTGTNRIKAGAPPGWTVAHKTGTGGYGPVNDIGLIQTPGRPPIVIAAYFHG -APGSDAAGEAAIAEATRRAL--- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium rhizosphaerae TaxID=395937 RepID=A0A3D9CWR1_9FLAO ----LEQKINTVTQGKNATVGVSVLDFDNKFRY-SKYGDQKFPMQSVFKFHIAAAILNFVD -QGKLSLNQKVLLDSSNLLEWSPLRDKYPNGNVPLSEILELTVARSDNNGCDIMLKLLGGP -QTVQKFMDSKGIKGFQIKYNEAEMHQNWNVQYENYSTPNSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN -SMETDAVNCKMISDISKEVWDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WRV6_9BACT ---------EEIARVSNGPVGAAAMEVETGEVV-ALNGKQRFPMQSVYKFPIGMAVLHQVD -TGVLKLDQKVRVKPTDLAPRSPLRDLHARGALTVRELLTFMMVDSDSSASDVLLATVSGP -QQATKYLRELGIEGINVATSEKQMATDDQVQYQNWSTPEAMLGLLKILQEGRSMSPASRD -LLLELMRKTWTFPTRIKGLLPAGTVVAHKTGSSGTRATNDVGLITLPNGHHLAVAVFVSD -TKVDEKTRDAVIAKIARAAWDCw ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. YR203 TaxID=1500291 RepID=A0A1M5G786_9FLAO --eNLRKEIKQIISTKNATVGISVKGIEDKDTL-SINGNLQMPMMSVFKFHIALTVLNQVD -KGKLKLNQKIFVKKEDLHAWSPMRDEFPDGNLTLDEILRYTVSHSDNNGCDLLLRMLGGT -ETVQQFINKQGIKDFTIKVNEQEMAS-WDNLYLNTTTPLATTELLEKFYKGKVLKKETTK -YLYQIMAETSRGITWLKAGLPEGTEIAHRTGISGRAAMNDVGIIKLPNGKHCILSLYLKN -ITEERTETEKTMADIAKAVWNYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium vrystaatense TaxID=307480 RepID=UPI0004E7289B --eNLRKEIKQIISTKNATVGISVKGIEDKDTL-SINGNLQMPMMSVFKFHIALTVLNQVD -KGKLKLNQKIFVKKEDLHAWSPMRDEFPDGNLTLDEILRYTVSHSDNNGCDLLLRMLGGT -ETVQQFINKQGIKDFTIKVNEQEMAS-WDNLYLNTTTPLATTELLEKFYKGKVLKKETTK -YLYQIMAQTSRGITWLKAGLPEGTEIAHRTGISGRAAMNDVGIIKLPNGKHCILSLYLKN -ITEERTETEKTMADIAKAVWNYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. PAMC 26617 TaxID=1112216 RepID=UPI0002881974 -----AAALAALERHHGGRLGVHALDMHTGRTL-GYRADESFKLMSSFKGLLAALVLSNVS -KGRDSLQSPVRYGPSDLMAASPVTQANVARGMTVRELCEAIMLRSDNAAANLLMRRSGGP -AGLTAFLRSIGDRVTRIDTYEGHLTDH--PLPADSSTPRAVTETVRRILCGPVLPIAGRR -LWEGWMAGNIVGRARLRASFPANWIAGDRTGTGD-GICNDFAFARRPGIAPLLLSAYYTA -PGSELPDQEAVLRAVSRLVV--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomycetes bacterium Pla52n TaxID=2528005 RepID=A0A5C6B6A8_9BACT --kDVSQKIEKLSQGLVGRIGVAAQEIGGDQVI-AVNGDETFAMASTYKVAIATTVLDRVD -KGELSLDQLVEVPPDMYVTGEALAETFPHPGLSVANLIEVMITESDNTATDVCMELAGGA -AAVTKNLRRLGITDFRVDRTTREILMDFEADPRDHATPLAMLQLLLAIDGGAAMSAESSA -FLLGVMSRTRTGAGRIKGMLPKGTPVAHKTGTVG-GIANDVGYVTLPDGRRFAIAVFTNS -SETPVVDRDRAIAEVGRTLYDFy ->[subseq from] HOA-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0L4_9ZZZZ --qNLKRDITKIIQSKNALVAVSVMNSKGKTEV-NINGNKKVPMLSVFKFHIALAVLDLVD -RGILDLEQNIFVKKSELLEWSPIRDKYPNGNIPLREIIEYTVSQSDNNGCDILLRLIGGV -DTVQKFIESKGIKDFAIKYNEEEMNKNGKSIYSNYTTANASSRLLQKFYNGEIISESSRD -FLFRIMYETSTGADRLISLLPPDVIVAHKTGTSGQAATNDVGIIILPDDEYYTISVFVIN -SKENTSTNEKIIADISKTVWDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. Ery12 TaxID=2306996 RepID=A0A419R341_9SPHN ---RLTAKLRLIEVGSGGTLGVMLLNTADGQTI-GHNSGERFAMCSTFKASLAALALDRAA -KGALDLDKVLYWRESDLQSYAPFAKERLVTGATIRELARAAQVLSDNTAANLVLGAVGGP -SALTQFWRSLGDDVSRLDNVEPLLNVVLPGRVENTTTPVAMARTLAKILFRGGVAPQAAQ -TLQQWMRETQTGTKKVRAGLPAEWVAGDKTGFSGQGVSADIGFAIPVDDAPIVFATYHRA -TTPPSPMADAAMAQVGGII---- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sp. Leaf339 TaxID=1736343 RepID=A0A0Q6K7B3_9SPHN ---------------------WATLDKATGRFS-GVNVNDRMPMCSTFKWLLVACVLARTD -RGLERLSQRISFGPDDLLGYAPTVRAALTAALSIKDLCEAAVTVSDNSAANLLLPVVGGP -EGLTAWLRRAGDPITRLDRNEPALNRVPPGDPRDTTNAAAMLGTLDRLLFGAVLSRGSRH -RLTDWLLACKTGADRLPAGLPAGWRAGHKTGTYTRNAAGDVGLLLPPSGKPILIVAYVAG -SRQPQPVVDRWFASLARDAV--- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. KBW06 TaxID=2153359 RepID=A0A3N7D035_9SPHI ---PLQQKLDSIVSTKKADVGFSVMYLENQKIV-SLNGDKHYPMQSVYKFHLALAVLNQVD -QGKLKLDQKIFVKKSDLLQWSPLREKYLNGNLPLSEILKYTVSESDNNGCDILFRLIGGT -GKADQFIKKQGIKEISITGTEEEMHKDDQVQFRNWTTPKAANNLLKKFLEGKVLKKTTED -FLMKIMEETVTGPGKIKGLLPKGTLVAHKTGNSGTAASNDIGIVTLPNGKKMLISAFVSM -SKESDQENDKIIAALTKAAFE-- ->[subseq from] Beta-lactamase n=1 Tax=Rheinheimera sp. YQF-1 TaxID=2499626 RepID=A0A437JKY7_9GAMM ---QLKEQIESIVANKSATVGVAVWGPNDLEPL-LLSPFEKFPMQSVFKLHLALLVLEQID -AGKLALNQSVAVKRKEVLQWAPMMKEHQGDEVTVEQLLRYSVSHSDNVACDLLFELVGGP -QALQAYVHSLGIREVAIVANEAEMHADDQIQYQNWTSMKAAALVLKQVEQKQLLSPTAQA -LLWKWMVETTTGPQRLKGLLPVDTEVAHKTGYSGTAATNDVGIIVLPDGRPLLVAVFVKD -SSESTKTNEAIIAQIAQAAYQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sediminis TaxID=1689985 RepID=UPI001325E300 ----LAAKLRIIEAAAGGTLGVSIRNTATGQTV-GYKADQRFGHCSSFKMSLAALVLKLDQ -DGTVNAQERIRWTRGDLMPVSPFTTSRVDKGATLLELAEATQKTSDNAAANFLLGRLGGP -ERLTRFWRDIGDEASRLDRTEPALNNVPPGEVRDTTTPHAMALTNERILFGDVLAAERRA -LLRQWMEETETGARRVRAGLPKDWNAGDKTGTSTGGLYVDIGFAVPPGGDANTFAAYYRS -PKGTDPVSENVLRQVGEVLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-9 TaxID=2610888 RepID=UPI00123C90BF ----ISNDIHKIEKHYGGKVGVYTINRNNWHNF-THNETFYFPICSVYKFLVVGAILKESM -TDKNLLNEKIRISKNQLVGYTPITKKYVGREMTVRELSKASI-LSDNTATNLLIYKLGGL -KKLDSFILSLNDHATKITELEPKVNNVNISNNLNKTTPKIITRDLNKIAFHDILDKKHRI -LFKKWLRENNTGSNRIAAELPKGWKIGDKTGTCDYGSTNDVAIVWPNNSRAIVMSILYTQ -PIKNAEPKDKVIQEVAKLLFDNf ->[subseq from] Class A beta-lactamase n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A520BZY8_9BURK ----TSPDFAALERSVQGRLGFFALDTGSGRTL-AHRADERFSTASTFKILLAARVAQGVE -GGRWAWEDELPLHKSERVPHSPAFDRLLAARATLGELVQGIVVESDNPCANILLRHCDSP -AGLTMWLRQQGDEVTRLDRWELDLNENAPGDLRDTSTPRAFAGTLRRLLLGDGLTRPSQA -RLWADLQASQTGLKRLRAGVPASWRVIDKTGTGYRGAVNDVALVFPPDGSPWVVVALQSD -SRASTDDLSAVHAEAMRQLVRAw ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. FP211-J200 TaxID=1792309 RepID=A0A177LGT0_9FLAO --dELRKELSKIITTKNATVGVSIKGIENKDTL-SINGNMNMPMMSVFKFHIALAVLNEVD -KGKLNLKQKIFIKKEDLKEWSPIREEFPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGI -EAVQKLINKNGIKDFTIKVNEEQMRT-WENLYINTTTPIATTELLEKFYKGKVLKKATTK -YLYQIMVECSRGITWIKAGLPEGTELAHRTGISGTNAMNDIGIIKLPNGNHFILSVYLKN -ITESREDTEKIIADITKATWNYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Cellulophaga sp. Hel_I_12 TaxID=1249972 RepID=UPI000647F2F1 ----LRSKIEQIVSDKNAVVGVSIMGNKVKDTI-SLHGDRRFPMQSVFKFHIALAVLSEVD -KGKLSLDQKIEINKNELLPWSPLRDENPNGGFTIERLIQYTVSHSDNTACDVLIRLIGTP -KTVEEYIKKNSIKDIQITFNEQDMQAKWGNMFENWTTPKAASETLKIFYENNLLSKTSHD -FFWKTNKETTTGNNRIKGQLPEGVIVAHKTGWSGTGAVNNIGIVFLPNGEYFIISVFVTE -SKESFDTNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WT06_9BACT ---RLQEQLNNLDSSAQGDVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD -EGKLSLNQTVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP -EQVTANLGKLNLRDIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLAKLQSRQLLSEDSTA -LLLKIMTDSPTGQQRLKAGLPPGWSIAHKTGTGAEVATNDVGLISSPTGKRIAIAVFIAG -SKAPLEQRESVMSAVASAVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. MK52 TaxID=2711156 RepID=UPI0013EA86DC ---ATSEALAAIERRAGGRLGAYILDPTTGRGT-GWRADDYFAQCSAFKLSLAAMILAGAE -RGLIDLNETLHWTEADLLSHSPVTRPATKTGLTVEALARGTLVTSDNPAANILLRRFGGP -EALTRFWRSIGDRMSRLDRTEPALNDVPPGSRLDSTTPRAMAQTAATLLLGPALSPASRE -TLKSWMRESATGLDRLRAGFPAGWDAGDKTGTWTRRIYVDVAFGGPAGAVPLIVAAYHET -RAGESGASAGVLAEVGRLAA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sanxanigenens TaxID=397260 RepID=A0A2W5A2Z0_9SPHN --qALSTQILTLEKQIQGRVGVAFRLVETGEGG-AVAGGERFPMASTYKVAIAGALLTLVD -KGQVSLDQMVSVTQRDFDQTGEVADRLIHPGLSVANMMELMLTQSNNSATDKMLELAGGP -AAVTTWLRANGIADMQVDRSVNDVLNAFEKDPRDTSAPTAMVDLLAKLLAGSLLKPESRT -FLIGVMERCETGQARLKGLLPQGTIVAHKTGTLG-GALNDVGMITLPGGGHLLIAVYTKS -SSLPGPQRERAIAEISRSLFDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI00063D3582 --kDLRNKIHEIVSTKNATVGVSLKGIEDKDTL-SINGNKNTPLMSVFKFHIALAVLNQVD -KGKLKLDQTFFIKKEELLPWSPIRDEYPQGNLTLDQLLRYTVSHSDNNGCDILLNILGGT -QTVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTALLEKFYNGKVLKKETTK -YLYRIMVETSRGLTWMKAGLPEGTELAHRTGISNRAAMNDVGIVTLPNGKHYILSVYLKN -ITEEMKDTEKIIADISRAVWEYy ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma lacussanchae TaxID=1884249 RepID=UPI001109FE48 --qRMERELERIARLGGGQVGVQAIHLESGQQI-SYNPQLKFPMASTVKVAIAVQLLQRIE -RGELSLMTMVDLKPSDLHPGSGTLTALFNKPLSVQNLLELMMVISDNSATDILLRLAGGP -EAVRNCLKSLNVQGMSVDRSIIELLAAFGTDPRDTSTPAAMVDLLAKIYQGKALKPESRD -VLLGVMERCRSGEARLRGFLPPNTVLAHKTGSLGATATDDVGYITLPDDGHIAIAVFIGP -STQPTAEREQTIAHMARAVYDYf ->[subseq from] Beta-lactamase n=4 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A077LCP2_ACIBA ----LKEQIESIVIEKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQAAYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B8LE97_9PLAN ---RLAARIKPLVSRHQGQVAIVVRHLDSGREV-SWQPDRPMPTASLIKLAVMVEVYRQVD -DDRVDLDDRLKLTADDAVPGSGVLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL -ESTNRTMSRLGHPNTRIHAKVFRRETSIDPERSGSTTASETADLLEAIRSGRAVSKRASR -QMLEHLRACES-TERIPRYLPEGTVVAHKTGSVSR-VRTDAGIIESPTG-PIVVCVLTAE -NQSAENAASRLIADISREAWLHf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3D2U0F2_9PLAN ---RLAARIKPLVSRHQGQVAIVVRHLDSGREV-SWQPDRPMPTASLIKLAVMVEVYRQVD -DDRVDLDDRLKLTADDAVPGSGVLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL -ESTNRTMSRLGHPNTRIHAKVFRRETSIDPERSGSTTASETADLLEAIRSGRAVSKRASR -QMLEHLRACES-TERIPRYLPEGTVVAHKTGSVSR-VRTDAGIIESPTG-PIVVCVLTAE -NQSAENAASRLIADISREAWLHf ->[subseq from] Beta-lactamase n=1 Tax=Xanthomonadaceae bacterium SCN 69-123 TaxID=1660170 RepID=A0A1E4L0D4_9GAMM ---EAQSRLAALEAKAGGRLGVFVLDTGSGLGL-AHRGGERFGLCSTFKLPLAAVILREHA -AGRLDGHAPIALASTPTVPHAPAVEAARAAGLSALELARATQTTSDNVAANLLLDLLGGP -ARFTALLRGLGDEVTRLDRYETEMNRVGPDELRDTSTPQAMARLTARLFGPGLLDASSQR -VLAHWMVETRTGLQRLRAGLPADWRAGDKTGTALSNRHNDVAVTWPPQRPPVVIAGYYEA -DGVMRAEDDAVLAEVGGLV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium scophthalmum TaxID=59733 RepID=A0A1N6IEU6_9FLAO ----LAQKVDSIIKGKKATVGVSVLGFEDGFKY-NKNATTKLPMLSVFKFHIAAAVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLSLSEIINYTVAWSDNNGCDVLLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISDISKAVWDHf ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter mirabilis TaxID=69666 RepID=A0A2D2AVK1_9CAUL ----LDKEIAVIADSVPAELEVAVQNLEGGEMW-AWNGQKAFPLQSVFKMVLGAAVLAEVD -AGRLALDDQITLTEADISPYSPVADAWPETEYTVRELLEKAVGDSDNTAADVLMKRIGGP -GAVTAWLRAKRIKEFRVDRYERELQPDYLADPRDTATASGVLNFLRQLSAGELLKPASTQ -LLLKIMTDSPTGEERLKAGLPPGATIAHKSATAATDATNDVGVVTLKDGRRYAVVVFLAA -SSQDDPTRDAAIAEAMRVIVK-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. OV705 TaxID=1500289 RepID=UPI0006472102 ----LGQKINAVTQGKNATVGVSVLDFDNKFRY-SKYGDQKFPMQSVFKFHIAAAILNFVD -QGKLSLNQKVLLDSSNLLEWSPLRDKYPNGNVPLSEILELTVARSDNNGCDIMLKLLGGP -QTVQKFMDSKGIKGFQIKYNEAEMHQNWNVQYENYSTPNSAVDVLKKFYNGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN -SMETDAVNCKMISDISKEVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium nematophagum TaxID=2305228 RepID=A0A3M7TI83_9FLAO ----LDKRINSIIKDKKATIGLSVLGFENGFKY-HKNGEKRFPMQSVFKFHIAAAVLHAVD -QGTLSLHQKIFLKKSDLLEWSPLRDKYPNGNVPLSEIIDYTVALSDNNGCDLLLRLIGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWKYQYENYSTPNSATQLLKKFYDGQLLSKESTE -YLMKVMLGTKTGLNKMIEQLPKNTPVARKTGASGTGAENEIGIVTLPNGNHYSITLFVSN -SIETDSVNCKIISDISKVVWDYf ->[subseq from] Beta-lactamase class A n=2 Tax=Pseudoxanthomonas indica TaxID=428993 RepID=A0A1T5KC02_9GAMM ---ALQLELDRFAAKFDGTVGLYALDLRTGRSA-VLNPADAFPMASTVKIPVAVHILSLVD -EGRLDLHRQVQLQEGDLYPGGPM-DTHLTPGITIRDLLHMMLTVSDNNATDILIRLGGGA -AAVNQRMQTLGVQGVRVDRYIWEMLSLYHQDPRDTSTPQGMAALLKLIWQGKALTPASTE -VLKAILLDCRTGQARLKGMLPDGTPVAHKTGTVGE-VINDVGVMTLPDGGDIIITVFLKS -GE-SDQARDRVIAQMARSVYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Elizabethkingia sp. YR191 TaxID=2135666 RepID=A0A2T5RUW7_9FLAO ----LDSKINAIVKDKKATVGVSVLGFENAFAY-NKNGNEKLPMQSVFKFHIASAVLDLVD -KGTLSLDQKILVKKEDLLEWSPLRDKYPAGNVPLSEIIEYTVALSDNNGCDFLLRLIGGM -EAVQKFMNGKGVKGFQIKYNEEDMHKDWNAQYENYSTPNSAVQVLKKFYNGKLLSKTSTD -YLMKVMLGTKTGLNKMVEQLPKDTPVARKTGSSGTGAENEIGIITLPNGNHYALAVFVVN -SMESDTVNCKMISDISKAVWDGf ->[subseq from] class A beta-lactamase n=1 Tax=Asaia TaxID=91914 RepID=UPI001269204A ----------RYEKISGGRLGVHIFCPENGTAL-SWRGEERFRMCSSFKASLAACVLARCD -RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAFEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASPDAGKSVIIATYTAG -GTPDETQFCRVFHDIGAL----- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR477 TaxID=1500295 RepID=UPI0006485C4B ----LEQKINSILKNKKATVGVSVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLDAVD -KGKLSLDQKIKLDSSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSQGVKGFQIKYNEEEMHKDWNVQYQNYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMKVLWSTSTGMNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCKVISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium formosense TaxID=236814 RepID=A0A085Z102_9FLAO ----LDQKISSIIKDKKATVGVSVLGFEDGFKY-DKNANKKLPTLSVFKFHIACAVLDLVD -QGKLSLNQKVVLKESELLPWSPIKEKYPTGDLTLDEIIDYTVALSDNNGCDKLLKMIGGT -QTVQKFMDSKGVKGFQIKVNEDEMHKDWKNQYKNYSTTKSAVTLLKNFDAGKILSKKSTD -YLMKIMLGTKTGMNKLVEQLPKNTPVAHKTGASGTVAENDMGIVTLPNGKHYAIAVFVNN -STETDVVNCKMISDISKIVWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI0012F8899C --dQLRSQIEQIARDAQGRVGVAATLLETGESV-GFHEMEQFPMQSVYKLPIGMAVLHQID -QKKLALTQVVHVTQSDYIAHSPIRDKFPQGVIPLSELLRYAISESDGSASDVLLRMVGGS -QVVMSYLKTLNVTEMMVLNTELEIGSDNAVQYRNWAKPAQAASLLRAVQEGRGLSKTSHA -FLLHLLTDTQTGLQRLKGLLPSGTTVAHKTGTSWTAATNDVGIITLPNGRHIALAVFVSD -AKADAKTREAVIARIAKVAWDYw ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. TaxID=1960881 RepID=A0A3C0UYR3_9BACT ----LRQRLQRVAATTQGMLGVGIVDLSNGDTV-SVNGQGRFAMQSVYKFHLALAVLSEVD -KGKWALEQKIKVTKKDLLPWSPLREKYPNGELPLREILEYTVAQSDNNGCDILFRLVGGT -KVVDKYIKSIGINEVNIVGTEEEMHADDRVQFDNWSSPRSAAKLLVVFDQKKILSKNSWE -FLWNTLVSTTTGPRKLKGVLPQGTIVAHKTGYSGQGATNDIGIVQLPNGKRFAIAVFLNN -TTLPEAECDRAIAEAAKVAWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia sp. ESBL41bB15_13_1E TaxID=1535126 RepID=A0A076V9Z9_9ESCH ------------------------------------------------------------- ----NLLNQRVEIKKSDLDNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SCP7_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLVKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTYWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Class A beta-lactamase n=1 Tax=Halieaceae bacterium GH4-78 TaxID=2547392 RepID=A0A4R5LR31_9GAMM ----VAAALDALTRGLIGYIGVAAEDMTTGKQV-FLNGEEPFPMASTYKVAIAVTLLAKVD -AGELSLTDMIELNDDEWVVSDIIASNFIHPGLSVANVMEVMITHSDNTATNVALRLAGGP -EAVNRQLEKLGISGMHVDRTTSDYSRAFEADPLDKSTPRAMLSLLTALYQGKTVSEESTA -FLLGIMSRTVTGPGRLRGLLPRKTPVAHKTGTLG-GVANDVGYITLPDGRRFAVVVFTRG -SHTLPSDRDRAIAEVARTLFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CEC91F8 -----------------------ALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVILTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga arvensicola TaxID=29529 RepID=A0A1I0SA55_9BACT --qTLRRQIAAIAGNISGKVGVYAEILETKDTV-SFNRDQRFPMQSVYKFPIAMAMLHAVD -QQKFRLDQLIHVTKEDLIGVSPVRDLHPEGNIPLSDLIDYNIRSSDGSACDVLLRLLGGT -ANANAYVHSLGVKQIAIATTEKVQVPSEMIQYQNWSTPAAMTQLLRIFYQEPVLSDSSHR -YLMHLLTTSGPGAKRLKGLLPAGTPVAHKTGTSWTRATNDVGIITMPNGQHVAITVFVSD -AKASEAEREGTIAKIAKAVYDHw ->[subseq from] Serine hydrolase n=1 Tax=Stenotrophomonas sp. ATCM1_4 TaxID=2259330 RepID=A0A4R4ICQ9_9GAMM -----QAEAQRLASLLGGELGAAIVHLESGRSV-YINGDRPFPMASTMKVPVAVHILALVD -EGTLSLQQQVTLKADDIYPMGGPMDLHLSAGITVRDLLHMMITVSDNNATDILIRLGGGT -AAVDARMRALGIDGLRVDRYIWELLAAWNADPRDTSTARAMTLLLEKTWKGQVLSPASLD -VLQAIMRDTRTGTARLPGMLPRDTPVAHKTGTVGD-VINDVGVITLPGGGHAVISVFVQS -RA-SSQERDAAIAQLARAAHDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Cronobacter malonaticus TaxID=413503 RepID=A0A649UI66_9ENTR ---ETLVKVKDAEDQLGARVVYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ ------------------------------------------------------------- ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium daeguense TaxID=412438 RepID=UPI0004148762 ----LAQKINSIIKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAVAVLDLVD -KEKLSLDQKILLDKSNLLEWSPLRDKYPNGNVPLSEILELTVAKSDNNGCDILLKLIGGT -QTVQKFMDSKGVKGFQIKHNEEDMHKDWKVQYENYSTTQSAVDVMKKFYDGKLISKKSTD -YLMKIMLSTSTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVTN -SMETDAVNCKIISDISKTAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus succinus TaxID=61015 RepID=UPI000D1EB684 -----ANEFDQLEKENSTTVGVYGINTESGKEI-KHLSDERFGYASTFKAIASGVLLNNYT ---EKEINKKIQIQQKDIVAYSPVTEKYVGKQMTLKALIEAAMLKSDNTANNYIIGEIGGI -SSFKAALQHLGDHVSDPQRLEPNLNNYDPTNTADTTTPRAAAHTLNELLTSNQMDTKNLN -LLKRVMIENETGDQLIKAGVPNHYLVGDKSGQGTYATRNDIAFIYPKKGKPIILAVYTKK -DDKEGTPDDKVIAKAAQIAIK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf404 TaxID=1736366 RepID=A0A0Q5ZQW2_9FLAO ----LDKKINAVVKDKKATVGISVLGFENGFKY-SKNAEKKLPMQSVFKFHIAAAVLDYVD -KGKLSLDQKVLLTKDNLMQWSPLRDKYPNGGVPLSEILELTVAQSDNSGCDILLGLLGGP -KTVQQFFDSKNVKNFQIISGEAEMHKDWKVQYKNYSTTNAAVDALKKFYDGKLLSEKSTE -YLMKVMLSTSTGKNKLIEQLPKNTPVARKTGSSGTGAENEIAIVTLPNGKHYAIAVFVSN -STESSEVNCKMISDISKVVWDYf ->[subseq from] Beta-lactamase class A n=2 Tax=Mucilaginibacter sp. OK098 TaxID=1855297 RepID=A0A1M7P419_9SPHI ----LRQQIKDVIKPAKGIVGVSILGLESRDTL-SVNGDARLVMHSVMKFPIALTVLHWVD -SGKLTLSQLIHIKKKDLPKYSPLRDKYPDGNVSVGDLLSYMVSLSDNDACDILLKVIDGP -KTVQDYMLHIGIRGIAVRASEADMASSWELQYTNWCKPFEMTILLDKFYKGEILAKPTTE -FLYKILTETTTGPHRIKGLLPAGTVVAHKTGTSPTSATNDVGIITLPNGKHLAISVFVCN -STDDETTRDAVIAKISKAAFDFy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. RU33C TaxID=1907398 RepID=A0A1N7AB37_9FLAO --sALDQKINSIIKDKKATIGVSVLSFESNFKY-SKNGDKKLPLLSVFKFHLASTVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIIKYTVAQSDNNTCDFLLRLIGGP -KVVQQFMDSKGVKDLQIKYTEDDMHKDWKNQYGNESSTNSTVALLKKFYDGKLLSKKSTD -FLMQIMLATTTGTNKIVEQLPKRTPVAHKTGSSRTVAENDMGIITLPNGKHYAIAVFVSN -STETERVNTRMVSDISKIVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. RP-3-8 TaxID=2530454 RepID=A0A4R0MIG2_9SPHI ---SLQEKLAQIIKGKKADVGVSVFFLGDRRSI-SVNGDQHYPMQSVYKFHLALAVLDQVD -KGKMALHQKIFVKKSDLLPWSPLREKYPNGNLPLSEIIRITISESDNNGCDILFRLVGGP -NKVHKYIAKLDIKDCAIAATEEEMHKDDKVQFTNWTTPKAANLLLEKFWNGQVLKKNTSA -FLMKAMEETVSGPNKIKGLLPSGTIVAHKTGYSGTAATNDIGIVRLPNGKRILISVFVSM -SKETEKVNDLIIAELARAAWD-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=UPI00103FDAC8 ----LEQKINSIIKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIMLNPSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QVVQKFMDSKGVKGFQIKYNEEDMHNDWNVQYENYSTTKSAADVLKKLYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISKEVWEYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0162 TaxID=2487063 RepID=A0A3G6SAN1_9FLAO --sSLEQKISAITKNKQATVGVSVLGFENQFKY-SQNGDKKLAMMSVFKFHVACAALDLVD -KGKLSLDQKVFIKKSELYNWSPFKTKYPEGNVTLYEIIDYTVALSDNNLCDILIELVGGT -QAVQKFMNSKGVKDFQIKHSERGMANGWDSLFENYTTTNSTVQLLKKFYDGKLLSKKSTD -DLMQIMLGTQTGANKIVEQLPKGTPVAHKTGSSSTIAENDMGIITLPNGKHYAIAVYVSN -SKESEAENCRIISDISKAVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Francisella tularensis subsp. mediasiatica TaxID=135248 RepID=A0A4Q7HFE3_FRATU ---QVTNDIQNIEKKYGGKIGVYTINRNDWNNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQIMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFNLSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNRIAAEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium frigidisoli TaxID=1125876 RepID=A0A1I3D866_9FLAO --eDLESQINKIIAGKNATVGVSILGIDKPFVL-NMNGEKHLPMQSVFKFHIALAVLNLVD -EGKLDLIQKILVKKTDLLEWSPIREKYPNGNLTLAEIIKYTVAQSDNNGCDILLKLIGGT -KTVQGFINSKGVKDFQIKFNEEEMHQDWKAQYENYSSTNSIVKLLKDFHGGKIVSKSSTD -FLMKIMIGTSTGTNKLIAFLPENIIIAHKTGSSGTGAENDMGIVTLPNGNHYAICVFVSN -SKETEEVNCKMIADISKLTFDHf ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000BF47462 -----HDSFAKLEKEYNAKLGIYALDTGTNQTI-AYHSNDRFAFASTSKSLAAGALLRQNS ---IEALDEGITYTREDLSNYNPITEKHVYTGMTLKELADASVRYSDSTAHNLILKKLGGP -SAFEKILRETGDTVTKSERFEPELNEVHPGETRDTSTPEAIAKTLQSFTLGSALPTEKRE -LLVDWMKRNTTGDKLIRAGVPKGWEVAD-------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sulfitobacter sp. JL08 TaxID=2070369 RepID=A0A345RGP3_9RHOB ---SVGAAIEQIVSGLAGRIGFAAQEIGGDEVI-SFNGDETFAMASTYKVAIATAVLDRVD -RGELSLDQLVEVPNEMFVTVVALAETFPHGGLSVANLIEVMITESDNTATDVNMGLAGGP -EAVTENLRRLGITDFRVDRLTAEILRDFEADPRDHTTPLAMLQLLLAIDGGTAMSPESRE -FLLGVMSRTRSGPGRIKGLMPMGTPVAHKTGTVG-GIANDVGYVTLPDGRRFAIAVYTNS -SETSTSDRERAIAEISRMVFDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1QSY6_9CYAN -------------SAAQGNVGIGVLDLNTGKSW-FRNGKQRFPMQSVYKVPIAIAVLKRVD -EGKLGLNQSVTVTRQDFAPWSPMAQEFKGNSFTVQDLLERSVGISDNTAADVLVRLVGGT -GQVNAILSRLKIRDVRVDRLERQLQSKYLTDPRDTATPEGIIDLLVKLQSNQLLSKKSTA -LLLKIMTDSPTGAKRLKAGLPNNWSIAHKTGSGPGTATNDVGVISSSNGKRVAIAVFIAG -SKAPVEAREKVMSDVASAVVK-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Mucilaginibacter gotjawali TaxID=1550579 RepID=A0A0X8X9D8_9SPHI ---ALRSRIEELSKPVKGIVGVSILNTETGDTL-SYNGKARLVLHSVMKFPIALTVMHLVD -SGVYTLSQVMHIPKRDLVKHSPMRDKYPKGVLPLSEIVKYMVAESDNNACDFLLKTIGGT -KTVQDYMLHIGIKGIAIRASEADMASMWELQYTNWCKPVEMTTLLDRFYRGKILAKSTTD -TLYKIMTETTTGPNRLKGLLPSGTVVAHKTGTSPTNATNDVGIITLPNGKHLVISVFVCN -STNDEATREGVISKIAKAAFDYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=UPI000F4E9783 --kDLKNKIHEIISAKNATVGVSLKGIEDQDTL-SINGNKKTPLMSVFKFHIALAVLNQVD -KGKLKLDQKFFIKKEELLPWSPIRDQYPKGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -AVVQKFINRQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTELLEKFYNGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIVKLPDGKHYILSVYLKN -INEEMADTEKIIADISRTVWEYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI0003B4E9F8 -----AARLRALERSAGGRLGAFVLDTGSGRHF-GWRADERFCHCSTFKLSLAALALREGD -AGRLDPAAMLAFGQADLVDHSPVVEAHLAAGLPVLALAEAVQVTSDNAAANVLMRRLGGS -AAVTRFWREIGDEISRLDGYEPTINEIPPGTTQNSTTPRAMAETVRRIVLGDVLATDSRE -RLRGWMAATRSGLGRIRAGIPAGWRGLDKTGTGMGNKTNDLAVLLPPGGAPLIVTGYFET -PSDVRPQDEAALKALGRLAIE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HLN6_9BACT --dSLRKQINEIVSTKKAVVGVAIVGGDGKDQV-VINGEKHFPLQSVFKFHIALLMLAEID -KGKFSLDQKIEIPKKDLLPYSPIRDKYPEGVLTIAEILEYTVSVSDNVGCDVLLRLLGGP -QAVEDYFTKNKFKDIAIKINEETQQANWDMQFQNWTTPKAANEVLSAFYYKKLLSQKSYD -FVWKTMRETSTGVKRIKGQLPAETVVAHKTGTSGTNAVNDIGVIFLPNGQHFFISVFVTD -SKEDADANEKIIADIAKAAWDHf ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. FH1 TaxID=1233951 RepID=A0A085B8L7_9FLAO ---ELRKKLNQIISTKNATVGISLKGMENKDTL-SINGNINMPMMSVFKFHIALAVLNEVD -KGKLALNQKVFIKKEDLKEWSPIREEFPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGT -KTVQKFINKIGIKDFTIKMNEDQMRT-WENLYINTTTPIATTKLLDKFYNGKVLKKATTK -YLYQIMVECSRGTTWMKAGLPDGTELAHRTGISGTNAMNDIGIVKLPNGKHFFISIYLKN -ITEPREDTEKIIADITKATWNYf ->[subseq from] Serine hydrolase n=1 Tax=Stenotrophomonas sp. TaxID=69392 RepID=A0A355YG33_9GAMM ----LQWELERLVAPFDGKVGAYVLDLRSGRRA-QVNGDAGFPMASTVKVPVAVHILALVD -EGRLDLRQQVVLQAADIYPGGPIDTHLTAGSITVRDLLHMMLTVSDNNATDILIRLGGGP -AAVDARMRALGIDGIRVDRYIWEMLALYNADPRDTSTPAGMAALLLRIWEGRALRPDTTA -VLKAILLDCRTGQARLKGMLPDATPVAHKTGTVDE-VINDVGVIVLPGGGEVVVAVYLVS -GA-SDQARDRMIAQVARAAYDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium lactis TaxID=1241981 RepID=A0A3G6RT29_9FLAO --sTLDQKINSIIKDKKATVGVSVLGFENNFKY-SKNGDKKLPLLSVFKFHLASTVLDMVD -KGKFSADQKFLMKKTDLLEWSPLREKYPDGNLSLEEILTYTVAQSDNNTCDFLLRLIGGP -QTVQNFMNSKGVKNLQIKYNEDDMHRDWKNQYGNSGTTNSSVELLKKFYDGKLISKKSTD -LLMQIMIGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVNN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Flavobacterium sp. 316 TaxID=1603293 RepID=A0A0D6TR83_9FLAO ----LRQKIQKIVATKNATVGISIIGNNAKDTL-SINGDKHLPMQSVYKFPIALAVLSEVD -KGKLSLNQKINITKEDLHQWSPIREKYPNGTLSLSEVIKYSVSDSDNIGCDILLKLLGGT -KKVEDYFYSINFKNISIKATEEEMHKEWNVQFQNWITPKAASELLELFYYKKLLSKESHN -FIWKVMSETWTGNKRLKGKLPIGTIVAHKTGTSDTNAVNDIGIVFTKNGHFFIISIFVTN -SKESAETNEKIIADIAKLTWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8ABB ---SLRNQIEQIAGTAQGRVGVAAMLLETGESV-ALLGDQRFPMQSVYKMPIGMAVLRLVD -QGKLTLDQKVRVETTEYVSHSPMRDQFPKGTVSVSELLRYSVSESDGSASDVLMRLAGGP -KSIMAYFKSLGIKDIIIANTEKEIGGDNAVQYRNWAKPTEVVGLLRLFQQGRGLSKSSRA -LLLRLMTETETGLHRLKGQLPAETVVAHKTGTSWTAATNDIGLITLPTGQHIALAVFVSD -SKADEKTREAVIAQIALATWDFw ->[subseq from] class A beta-lactamase n=2 Tax=Haloactinobacterium sp. HY164 TaxID=2675754 RepID=UPI0012B7F991 -------ALVRLEEESGVRIGAVGIS--AAARV-DHRAEEAFPMCSLFKVLAVAALLRERA -YDDAYWAEPIPFGPADLVEDSPVTSATTTWAMSPTALADAALRFSDNTAGNLLLAELGGP -EAITTFAADLGAANTRLDRWEPELNEATPGDLRDTSTPSDIALLYRALLLEDRAGALAGA -RLRDWMLRNTTSAARIRAGLDGDVELADKTGAGSYGVVNDAGVLWTGGPDPVTLVILTRT -DDPAAVNDNEVVAEATRIIMS-- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7NKA6_9PLAN ---RLAARIKPLVSRHQGQVAIVVRHLDSGREM-SWQPDRPMPTASLIKLAVMVEVYRQVD -DDRVDLDDRLKLTADDTVPGSGVLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL -ESTNRTMSRLGHPNTRIHAKVFRRETSIDPERSGSTTASETADLLEAIRSGRAVSKRASR -QMLEHLRACES-TERIPRYLPEGTVVAHKTGSVSR-VRTDAGIIESPTG-PIVVCVLTSE -NQSAENAASRLIADISREAWLHf ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=A0A161VQY2_9NOCA ---------RNLEQRFDARVGVSAFDTETGATM-SYRGSERFGFASTLKAFAAAEFLRQTS ---TEDRDELVRWTRSDIDRYSPVTTENLDTGLTAAELAEAAVRESDNTALNLVLDRIGGP -EGLDDALELLGDATTEVVNYEPELNTITSGSIDDTTTADAFTESMTALQQTSYSTSSNRS -ILLDWMSGNKTGDPLVRAGAPAGWVVADKSGGAGP-IRNDIAVVTPPERSAVVITILTEK -NDPAAQFDNELVSETAAVVLH-- ->[subseq from] Class A beta-lactamase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A514ZUZ3_9BACT --qRLEQELERIAKLAKGKVGICALHLESGKQI-SLNVQDRFPMASTIKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQNRVKALGIKGMSVDRTIIQLLAKIKTDPRDTSTPDAMVNLLAQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPLAEREQTIAHTARSIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium flavum TaxID=415851 RepID=A0A3D9CI51_9FLAO --sALEQKINMITKGKNATVGVSVLGFENPFKY-SKSGDQKFPMQSVFKFHIAAAVLDFVD -QGKLSLDQKIPLNASNLLKWSPLRDKYPDGNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -KTVQHFMDSKGVKGFRIRYNEEDMHKDWSVQYENYSTPNSAVTVLKKFYDGKLVSKKSTD -YLMKVMLSTSTGLNKIIEQLPKNTPVARKTGASGTGAENEIAIITLPDGKHYAIAVFVSN -SMETDTVNCKMISDISKEVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI000B597F20 ---EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEELGGL -NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WXY1_9BACT ----LERAIKRLAESSGGIVGVSAIHIESGRRV-SVNGDLRFPMASVYKLPIALRLLQRID -RGELRLDGPITLSTHDFRPHSPIAEFANNKPLPLERLLELMLGESDNSASDKLLALAGGP -AAVTARMRALDITGLDISRPEGRLALAFADDPRDTSTPDAMAQLLVRVERREVLEPASME -RLLQITTATQTGPLRLKGLLPAGTPVAHKTGTMG-ATTNDVGIITLPDGGHVALAVFVKG -STLDVPSRERVIAEIARTIYDYy ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium soli TaxID=445961 RepID=A0A086A765_9FLAO --sQLEQKISSFTKDKKATVGVSVLGFENGFKY-NKNGDRKLPMQSVFKFHIASAVLDLVD -HGKLKLDQKIFIKKSDLLEWSPLRDKYPAGNVPLSEIIDNTVALSDNNGCDILLQLIGGT -QTVQKFMDSKEVKGFQIKYNEAEMHQDWNAQYENYSTTNSAVQVLKKLYDGKLLSKQSTE -FLMNIILGTKTGVNKMIEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN -STESNEANCKMISDISKAVWDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR459 TaxID=1500292 RepID=UPI00064908AD ----LEQKIHSILKNKKATVGVSVLDFENGFKY-DKNADKKLPMQSVFKFHIAATVLNAVD -QGKFSLDQKIVLNKSNLLEWSPLRDKYPGGNVPLSEVIEYTVAKSDNNGCDILLTLLGGT -QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISKEVWEYf ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. MYb7 TaxID=1827290 RepID=A0A2S8ZUJ9_9FLAO --kELRNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNQVD -KGKLKLNQKFFIKKEDLLPWSPIREEYPQGNLTLDQLIRYTVSHSDNNGCDILLNIIGGT -ETVQKFINLQGIKDFTIKVNEKEMAS-FEKCYLNTTTPLATTELLEKFYKGKVLKKESTK -YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGTIKLPNGKHIVLSIYLKN -INEEMTDTEKIIADVTRAVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Nocardioides sp. zg-579 TaxID=2663857 RepID=UPI0012B615BA -----DRRLAALEERYDARVGVSLLDTGDGAAY-SYRGDQRFGFASSVKVLVAAELLRRTG ---SAERAELVRWTQDDVDAYSPVTEAHVDRGLPLLRLAEAAVRESDNTATNLVLERLDGP -AGLTRGLLGRGDTTTVLADDEPGLNEVSPGSPANTTTPDAFVADLRALLGPEWLTDADRR -LLLGWMSGNPGGDPLIRAGAPAGWRVAQKSGGAGP-VRNDVAVLTPPDGAPVLLAVLTTR -LDPSAPYDDALVADAAEVAL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. 5_R23647 TaxID=2258964 RepID=A0A3D9AIC9_9FLAO ----LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNAETKLPMLSVFKFHIAAAVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGA -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKNFYNGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISDISKAVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter steynii TaxID=430522 RepID=A0A1H0CQ05_9SPHI ---ALQIKMDSIINSKKADVGVSVLYLSDQRIV-SVNGDKHYPMQSVYKFHLALAVLNQVD -QGKFKLDQKVLIKKSDLLPWSPLREKYPNGNVPLSEILKYTVSESDNNGCDILFRLIGGT -SKAHQFIKKQGIKEISIVGTEEEMHKDDQVQFRNWTTPKAANDLLKKFQEGKVLKKTTGD -FLMKIMEETVTGPGKIKGLLPQGTLVAHKTGNSGTAASNDIGIVTLPNGKKMLISTFVSM -SKENDKENDKIIAELAKAAFE-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XFH3_9BACT --kTIEQRLNEIATQVPAKLGVAVFDFQTGKQI-GLHADERFPMQSVFKAPLAAAVFSLAE -QGKLSLDQKVTLEEKDLSAPESINEQWPGNRYTILELIEKAVAISDNTAADLLLSRVSGP -EGVDQYLEKHGIHGMHLDRSERELQPNYLSDPRDTTTPQAALTFLKKLESGELLSKDHTQ -QLLKMMSSNRYGTHRLKAGIPADAIFAHKTGTARVDAVNDIGIITLANGKKYAIASFLSG -TTLNDVEREAIHSEVARSVF--- ->[subseq from] class A beta-lactamase n=1 Tax=Kozakia baliensis TaxID=153496 RepID=UPI0013144F60 -----KQLISGIERKLGGRVGVSAVDTQTGLIL-QWRGSERFVMHSVFKWLLSAYLLHCSD -TGSRPLQTRVVIRASSIVGHSDQTKPFVGAAITLETLCLWMMSTSDNGAANTLLDVIGGP -YVLTAWLRSLGDTTTRQDTYEPGPTEG-SIDPRNTTTPDAMLALTQKIWLGSVLSPRSRE -TLLAWLRGSAVGGRRLRAGVPSSWVEGDRTGTGDPGVANDVAIFWPDGRKPILVSSFLEG -SANDLARLEDAQASIGRILANLf ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X6D3_9BACT ---DFKSQLESITKQIDGIAGVAVKDLEGKETL-ILNADHKFPMLSSFKFPIAMAVLDQVD -KGKLALDQKYHLTKEDIQLYSPLRDKFPDGNLTIADLLASMVSLSDNIACDILFKLAGGT -KPVQDYVHSLGVKDIAIVANEEQMGQDWNVQYTNWCKPGAMLQLLDIFYKGKNLSKSSHD -FLSKIMIDGPTGMNRIKGQLPKEAVVAHKTGTSGTNVVNDVGIVKMANGKSFAIVLFMSN -STAELKAIESVMAQVSKAAYEHy ->[subseq from] Putative beta-lactamase n=1 Tax=Scytonema sp. NIES-4073 TaxID=2005464 RepID=A0A1Z4PUC0_9CYAN -----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD -EGKISLKQLVTIMRQDFAPSSPMIKEFKGDRIPLRNVLESSVGISDNTAADALVRLLGGP -QQVNAILGKLQIRNIRVDRLEQQMQPKYLTDPRDTATPEAMVDLLAKLNSNQLLSENSTA -LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGAGTATNDVGIASSPDGKRVAIAVFIAG -SKAPLEEREKVMSNIASRVVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacteraceae bacterium CCH12-C2 TaxID=1768805 RepID=UPI0008311D6A ----LAAELRIIEAAGNGTLGVEIYDTGSGLSV-GINQDRRFGHASSFKLSLAALLLQRHA -AGLIDADRRVTWTEADMIPHAPFTRERIATGATLRELARATQTTSDNPAANILLRQLGGP -AGLTQFWRSIGDEVSRIDRYEPEMNLVPASEFRDTTTPAAMARTVAKIVYGDVLPEAERA -ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKAAPITFACYFRA -RQTEQPIGEQTLARVGKVI---- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella limosa TaxID=370978 RepID=UPI00041CE8F3 --sALRQQLQRVAATTNGVLGVGVIDLSNGDTV-SVNGQGHFPMQSVYKFHLALAVMNEID -KGKWTLEQKIKVTKKDLLPWSPLREKYPNGELPLREILEYTVAQSDNNGCDILFRLMGGT -KVVDKYIKSIGISDVNIVGTEEEMHADDRVQFANWSTPRSAAKLLAVFFEKKILSKHSWD -FVWNTMVSTTTGPRKIKGVLPANATVAHKTGYSGVNATNDIGIMQLPNGKYVAIAVFLSN -TPLPEAQCDRVIAEAAKVTWDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. Root420 TaxID=1736533 RepID=A0A0Q7FM44_9FLAO --nDLRQQLNQIIASKNATVGISIKSIEDKDTL-SINGNLKAPMMSVFKFHIALTVLNQVD -EGKLSLDQKIFIKKKDLHEWSPMREDYPEGNLTLDKLLRYTVSHSDNNGCDLLINLVGGT -KVIQKFINKQGIKDFVIKVNEQQMET-WKNLYVNTTTPLTTTELLEKFYKGEVLKEETTK -YLYEIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKE -ITETKEDTEKIIADIAKATWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI0013304E02 ---EISNRLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNEEVKISANQIIGYSPVTKKHLNQTMTVSELSKAAI-QSDNTATNLLIEKLGGL -NNLNTFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMGIFYTQ -SQKDAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=F8T7L4_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQAAYQ-- ->[subseq from] Class A beta-lactamase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2D9RBG3_9RHOB -------ALQALEASAGGRLGVSATNLQTGRSI-SWRGDERFAMCSTFKWLLGAFYAQRMR -AQKERWDRFIPYTQADIVSYSPVSEPLVNGGMTLEGLCEATIMTSDNTAANVLLKDIGGP -EALTTFIRETGDLVTRLDRFEPELNIFVPGDERDTTTPNAMSGLMAHLLFGETGAFNATR -RVHDWMIKANTGLKRLRAGISDDYLVGDKTGTNSDSHSNDVGFVYTHKGGPVVISSYYNT -DDPFNPASDEVHAEVGRIAMK-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium sp. MOF25P TaxID=1664318 RepID=A0A1A7KDN8_9FLAO ----LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNADTKLPMLSVFKFHIAATVLDLVD -KGRLSLDQKILIKKSDLLEWSPIREKYPNENIPLSEIINYTVAWSDNNGCDILLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYEGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISNISKAVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1Z3GWX7_ECOLX ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWDYy ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140AQ53_ECOLX ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWDYy ->[subseq from] Beta-lactamase n=3 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1B1SDU0_VIBPH ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWDYy ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A0A0B5WYI7_PROMI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWDYy ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E3V8P1_9BACT --qRLQQELERIAGLAKGKVGICALHLESGKQV-SLNLQERFPMASTIKVAIAVQLFTMIE -KGQLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -QAVQNRVKALGIQGMSVDRTIIQLLAKLKTDPRDTSTPEAMVNLLTQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPSTVIAHKTGSLDGSATDDVGIITLPDNGHIAIAVFVGD -SPMPLAEREQTIAHAARSIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E2ZJ48_9GAMM ---EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL -NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLIENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E1N5Y6_9GAMM ---EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL -NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=C1KGB9_ACIBA ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGTAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=1 Tax=Francisella noatunensis subsp. orientalis TaxID=299583 RepID=A0A5C1S7D4_9GAMM ---EISNRLHNLEKQCGGKIGVYTINRNYNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNEEVKISANQIIGYSPVTKKHLNQTMTVSELSKAAI-QSDNTATNLLIEKLGGL -NNLNTFILSLHDHATKIAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILNKKHRL -LFKKWLLESDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNNKIIREVTKILLD-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A333W4D3_ACIBA ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGTAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium hominis TaxID=420404 RepID=A0A3N0X7K2_9FLAO --eELRKELNQIISTKNATVGISIKGSQEKDTL-SINGNMNMPMMSVFKFHIALAVLNEVD -KGKLLLTQKFLIKKEDLHEWSPILEEFPNGNLTLDQLLRYTVSHSDNNGCDILLKLIGGP -ETVQKFINKNGIKDFTIKVNENQMRT-WENLYINTTTPIATTELLEKFYKGKVLKKSTTK -YLYQIMVECSRGTTWMKAGLPAGTELAHRTGISGTNAMNDIGIIKLPNGKYVILSVYLKN -ITESREDTEKIIADIAKATWNYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacteriaceae bacterium TaxID=2021370 RepID=A0A4Q3EML0_9SPHI --nSLKNQVIEIAKEAKATIGISIFNIETRKRV-SYNENLHLPMQSVMKFPIAITVLHKID -EGKLKQDQLIHIDKEDLPEYSPLRDKFPEGNVSIKDLLSYMVSLSDNDACDILLKTIGGP -KQVDTYMHQLSVKNISVKASEFQMAQNWNVQFTNWCEPAAMTQLLDLSLRANFLSRNSHA -FLWKILQETSTGPKQLKGLLPEGTIVAHKTGRSGTAATNDVGVITLPNGKHLAIAIFISN -SSVDLATRESVIARIAKAVYK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Tropicimonas sp. IMCC6043 TaxID=2510645 RepID=A0A4V1V621_9RHOB ----VAAAIERVATGLAGRIGFAAQEIGGDQVI-AFNGDETFAMASTYKVAIATAIMDRVD -RGELGLDQMVEITPDMMMIDAALSDTFVHPGLSVANLMEIMITESDNTATDTLIGLAGGA -AAVTENLRRLGITDFRVDRTTGEIIGDFEADPRDHATPLAMLQLLLAIDSGTAMSAESRD -FLIDVMSRTRTGAARLMGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTSS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus sp. MEB064 TaxID=1587522 RepID=A0A0D0KLP2_9NOCA --eDFSTELQAVEDRYDVTVGVSLLDTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP ---QDARDDIVRWSAADIERYSPVTTARLDTGLTAAELAEAAVRASDNTATNLVFDRIGGP -AELDAALSRLGDEVTDIVDVEPGLNTVEPDSTANTTTADAFTANMAALRGDGSSTDADAA -TLVEWMSGNATGDALVRAGAPSGWTVADKSGGAG-GVRNDIAVVTPPGHPPLVLTVLTRK -NDPSAPYEDAAVSESAAIVLN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X1K5_9BACT --sKLAAQVEKIAGEARGRVGAAVMLIETGEAIvSLNADQRFPMQSVYKLPIALVVLRRVD -RGALALEQRVRVEQSDFISHSPIRDKNPRGVMSLRDLLRFAISESDGTASDVLMRLAGGA -DVITRELRELGVSGVMVVNTEKELGENQSLQHQNWATPESMLVLLRALQEGRGLSVQSRI -LLLQLMAESTPGPRRLKGRLPPGTVVAHKTGTSGTAATNDVGLITLPDGRHLAIAVFVSD -SPADESVREGVIARIARAAWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2LAX3_9CYAN ----LQERLKNLISAAQGRVGIGVLDLNNGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD -EGKISLKQLVTIMRRDFAPWSPIIKEVRGDRFILRNVLERSVGMSDNTAADALVRVLGGP -KQVNAILKQLSIRNVRVDRLEQQLQPKYLRDERDTATPEGMVDLLARLNSNKLLSQNSTT -LLLKIMTDSPTGEKRLKAGLPNNWSIAHKTGTGPGTATNDVGIASSPDGKRVAIAVFIAG -SKAPLEVREKVMSEIASAVIQ-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium ginsenosidimutans TaxID=1176536 RepID=A0A5B8S350_9SPHN ---TLEATVASLADAAQGRIGVAAMDLGTGRTV-AVLGDQPFPMASTSKIAIAATFLDLVD -QGKRSLSDRFPLMIPQRSASSAVAPVRPGTMISAQGLIELSITRSDNPATDALLAAVGGP -AAVNRWMRKAGLSGMRLDRDIATLVRATTVDLRDSATPLAMVQLLAGLHQGRWLSASSRS -VLLGAMERCVTGKRRLRAMLPEDARIAHKTGTLNN-TSSDVGIIQTPDGRSIAIAVYVTG -QG-GKPNRDYRIASISRAIYDGy ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes xinjiangensis TaxID=512350 RepID=A0A316FFZ9_9ACTN -----HSRLAELERRFGARLGVYAVATGTGATV-AHRADERFPYCSAFKGLAAAAVLHGTP ---LSGLTERVRFTRADVEPNSRKTRERITTGMTLGELCDAAIRFSDGTAGNLLLRRLGGP -AELTAYLRTLDDTVTLAARTEPALWRDTPGDRRDTTSPRAIGTDYQKIMVGDALPGNARA -YLRDLLERADESRERIRSVIPRGWTVANKTGTGDYGPANDIALVWQSASDPLVLSIMSRR -TGREGEADNTLVAEAARYVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000A6D6424 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS -LLKQIMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] CIA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI000B515EB2 ----LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLNKKSTD -FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D62C0D --kELQTKIEQVIKNKKATVSVGIYNFGNHQTL-LINGDKHVPMQSVYKFHVALAVLKEVD -KRRFKLTQKMHVKKSDLTPHSPMGEDYPNGELPLSDIIRYMVADSDGSACDYLFRLLGGP -KQVEAFIHQLGIRDVSIRDTEAMMQANWNVQYTNWTTQTAMLSLMKLFYQHKILSASSHK -FLWNVMLGTTTGQDRLKKLLPAGTLVAHKTGTSGMGAVNDAGFIALPNGGHMAISVFVTN -STERMATNEKIIADIAKLAYDHy ->[subseq from] Extended-spectrum class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9MB51_9FLAO ----LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD -FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] CIA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI00076E375B ----LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD -FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Mastigocladopsis repens TaxID=221287 RepID=UPI000526D6C8 ----LQERLKNLDSAARGKVGIGVLDLNSGKSW-FLNGKQRFPMQSVFKLPAAIAVLRLVD -DGKVSLDQSVTITRQEFAPSSSMIKEFKGTSFTVRKLLERSVGMSDNTAADALVRLVGGP -QQVNAILGKLKIRDVRVDRLEQQLQPKYLTDPRDTATPEGIVDLLAKLHSNQLLSRNSTA -LLLKIMTDSPTGQKRLKAGLPKNWWIAHKTGTGPGTATNDVGIASSPDGKRVGIAVFIAG -SKAPLEEREKLMSEIASTVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X1S5_9BACT --sALQNQIKEIAAEAKGKVGVTAVVLESGETVaSLNPQEHFPMQSVYKLPISMAVMKAVD -AGKVKLTDKVTISKSEFVGHSPIRDQHPNGALTVEELLRYALSESDGTASDVLMKLAGGP -AAVQA-LTELSIKDLIVLDTEQTFTQDKTAQYRNWATPEAAVALLRALHESRGVSESSQS -LLLKFMTESTPGAKRLKGMLPAGTPVAHKTGTSGTAATNDIGIITLKNGKHVAIAVFVSD -SPADQVTREGVIAKIAKAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RJ99_9BACT --pQLENELAEIARQARGRVGVAAKLLGSKQTV-LLNSAEHFPMQSVYKLPISMAVVQQVD -QGKLKLDQMVRVAKDDFIGRSPIRDKFPNGVLSVSDLLRYAISESDGTASDVLMKVAGGP -EIIQSFLTTIGIADMKIIDTEKALARDRSLQYRNWTTPDAAVALLESLDEKRELSQTSRS -LLMKLMAESTPGKNRLKGLLPAGTYVAHKTGTSGTAATNDIGIITLPNGQHLAIAVFVSE -SPAVETTREGVIAQLAKRVFETw ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf201 TaxID=1735672 RepID=A0A0Q4C684_9FLAO ----LKKQINTIIKGKNATVGISVLNLEDGFSY-DKNAGKKLPMQSVFKFHIAAAVLDLAD -KGKLSLDQKVTLDASNLMEWSPLRDKYSGKNVPLSEILEFTVAKSDNNGCDILLQLLGGT -ETVQKFMDSKGIKGFQIKYNETEMHKDWTAQYENYTTAKSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPENTPAARKTGASGTGAENEIAIITLPDGRHYAIAVLVSN -STETNAVNCKMISDISKTVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoxanthomonas yeongjuensis TaxID=377616 RepID=UPI001391E434 ----LQQELDRLVSSFDGEAGVYALDLRSGRTA-HANAEVGFPMASTVKVPVAVHILGLVD -EGKLDLRQQVLLKEGDIYPGGPVDIHLTPGSITLRDLLHMMLTVSDNNATDILIRLGGGA -AAVNARMRALGVQGIRVDRYIWEMLSLYNDDPRDTSTPAGMASLLRLVWEGKALKPATTD -ALKTILLDCRTGQDRLKGMLPEATPVAHKTGTVDE-VINDVGVITLPAGGDVVVAVFLKS -DQGD-RARDRMIAQVARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter freundii complex sp. CFNIH2 TaxID=2066049 RepID=A0A2K9PJC7_9ENTR ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLG----- ------------------------------------------------------------- ------------------------ ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X5T9_9BACT ---DFKSQLESITKQIDGIAGVAVKDLEGKETL-ILNADHKFPMLSSFKFPIAVAVLDQVD -KGKLALDQKYHLTKEDIQLYSPLRDKFPDGNLTIADLLASMVSLSDNIACDILFKLAGGT -KPVQDYVHSLGVKDIAIVANEEQMGQDWNVQYTNWCKPGAMLQLLDIFYKGKNLSKSSHD -FLSKIMIDGPTGMNRIKGQLPKEAVVAHKTGTSGTNAVNDVGIVKMANGKSFAIVLFMSN -STAELKAIESVMAQVSKAAYEHy ->[subseq from] Beta-lactamase n=1 Tax=Halioglobus sediminis TaxID=2283635 RepID=A0A3L7DVG7_9GAMM ----VAAAIERVVTKLAGRIGFAAQEIGGDEVI-ALNGNETFAMASTYKVAIAAAVLDRVD -RGELRLDQMVDVTLDMMMIGDAALNTHPGLQLSIANLIEVMITESDNTATDISMGLAGGP -AAVTKYLRRLGITDFRVDRLTGEIIGDFEADPRDQATPLAMLLLLLAIDSGTATSPESRD -FLIDVMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSETDRDRAIAEVARSLFDYf ->[subseq from] VEB family class A extended-spectrum beta-lactamase n=1 Tax=Aeromonas hydrophila TaxID=644 RepID=UPI00090A8AF3 ---NLTLKIENVLKEKNARIGVAIFNSNEKDTF-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus nepalensis TaxID=214473 RepID=A0A3A0SD35_9STAP ----SAKTFEQIEQDNDTIVGVYGVNTANGKHI-QHRSDERFAFASTYKAIASGILLQNTA ---TSTLNKKIDIKKDDIVANSPVTEKYVGSQMTLKALIQASMLQSDNTANNKIINEIGGI -KGFHEELKQLEDNISNPQRLEPELNLYDPTSTADTTTPKAAAMTLKHILTNEDMSKANRN -LLKNVMIHNETGDTLIKAGVPKQAVVGDKSGQGTYGTRNDLAFIYPKNQEPIVLAIYTKK -DGKDAKPNDKVIQMATKTAME-- ->[subseq from] Beta-lactamase n=1 Tax=Asaia bogorensis NBRC 16594 TaxID=1231624 RepID=A0A0P0YGZ0_9PROT -hqALSDIATRYEKLSGGRLGVHIFCPESGTAL-SWRGEERFRMCSSFKASLAACVLACCD -RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASADAGKSVIIATYTAG -GTPDETQFRRVFHDIGALA---- ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia (strain ATCC 25017) TaxID=484022 RepID=B0TZF6_FRAP2 ----ISNHLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLNKEVKISANQIIGYSPVTKKHINQTMTVRELSKAAI-QSDNTATNLLIEKLGGL -NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNSKIIREATKILLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter arachoides TaxID=1850444 RepID=UPI00103CBDA4 ---RIEQRIAQIAEGSRGRIGVAAIDLATGQEI-SVLGDQRFPMASTSKIAIAATFLEMVD -QGRASLSSEYPMLYAVSSRSTSVAPVRRGEYMSAANLIEIMITRSSNQATDALLQAVGGP -GAVNAWAQRAGLTDFSLDRDIATLVRAHHIDLRDSATPQAMVQLLSGIYQGRWLSAESRR -VILGAMERCRTGTRRIPAMLPSGVSVAHKTGSLNN-TSSDIGILTAPDGRTIAVAIYVTG -QG-SRPNREARIASIARAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0H4IVL0_PSEAI ---NLTLKIENVLKEKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. KLBC 52 TaxID=1862702 RepID=UPI000E0A87C0 ----LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLNDVD -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTLVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Sporocytophaga myxococcoides TaxID=153721 RepID=A0A098LJH2_9BACT ---SLRRDIEKVLSTKKAKVGVSIMGDNGRDTL-SINGDKHFPMQSVFKFHIALTVLSQIE -QGKFSLDQIIKIDENQMLPYSPIREKYPHGVLKISEILEYTVSLSDNVGCDVLLKLIGGP -QVVENFITEKGFKDFSVKINEEVMQNNWDLQFKNWTTPKTSTQILAYFYDKKILSAEHHD -FIWTIMKQTETGKNRLKGQLPEGTVVAHKTGWSGTAAVNDIGIIFLPNGRHYFISVFITD -SKEDTAVSEKIIADISKVVFDYf ->[subseq from] Beta-lactamase n=1 Tax=[Flexibacter] sp. ATCC 35208 TaxID=1936242 RepID=A0A1V2BD02_9BACT ---ALRKTIDSIATHSNAHIGVAALLLETGDTL-TYRGNDHYPMQSVYKFPISLAILHQVD -IGKYKLDEKILITKDDIMPHSPIRDAHPNGGMTLREISRYNIMESDGTACDVLLRLLGGT -KKTNAYIKSLGVKGINIATTEKEQQSNDTTQYRNWATPIGITQLYKIYLQNKVLSSASYN -TLWKDLAGSYPGANRIKGLLPKGTIVAHKTGTSGTAATNDSGIIILPNGKHLILTVFVSD -SKGSDAEREAWIAQISKAIFDHw ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. CBo1 TaxID=1869230 RepID=A0A1B9Y8A5_9FLAO ----LDQKISSIIKDKKATVGVSVLGFEDGFKY-DKNANKKLPTLSVFKFHIACAVLDLVD -QGKLSLNQKVVLKESELLPWSPIKEKYPTGDLTLDEIIDYTVALSDNNGCDKLLKMIGGT -QTVQKFMDSKGVKGFQIKVNEDEMHKDWKNQYKNYSTTKSAVTLLKSFYDGKILSKKSTD -YLMKIMLGTKTGMNKLVEQLPKNTPIVHKTGASGTVAENDMGIVTLPNGKHYAIAVFVNN -STETEVVNCKMISDISKIVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium aquidurense TaxID=362413 RepID=A0A1H3S746_9FLAO --sDLRQQLNQIIATKNATVGISIKSIEDKDTL-SINGNLKAPMMSVFKFHIALTVLNQVD -EGKLSLEQKIFIKKKELHEWSPMREDYPEGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT -KVIQKFINKQGIKDFVIKVNEKQMES-WKNLYVNTTTPLATTELLEKFYKGEVLKESTTQ -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKD -ITEKQEDTEKIIADIARATWDYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8QR85_9BACT ----LQQRTTQIAALAKGRVGVSAVLLETRELIaSLNSQDHFPMQSVYKLPISMALMKQVD -AGKIKLEQRVKIAKEDYVGHSPIRDQYPNGTLSVTELLRFALSESDGTASDVLMKLAGGH -EAVQAYLTDLGIKDMMILDTEQSFTQDHSLQYRNFATPDAAVDLLRALYEHRGLSESSQA -LLLKFMAESTTGPKRLKGLLPAGTTVSHKTGTSGTAATNDIGLITLPNGKHVAIAVFVAD -SPADEITREATIAKIAKAVWD-- ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E2NDE0_9SPHN --eQLAAQIDGLEAASGGRLGLALFSRDEGLVF-AHRGAVRFAMCSTFKLALAAMTLETAD -----VREERLDFGADDILSYAPYAKERAQIGMSGLEAAHHAVTLSDNTAANLLLVRLGGP -EAFTAWLRDAGDRVTRLDRNEPTLNENAPGDPRDTTTPGAKAELVGNLLWGDRLSATDRG -ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPSGSRYVLAAFLDR -PKGTSAEADAVLADAARVVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. PAMC 26621 TaxID=1112213 RepID=UPI00028896DC -----AAALAALERRHGGRLGVHALDMHTGRTL-GYRADESFKLMSSFKGLLAALVLSNVS -KHRDSLQSPVRYGPSDLLAASPVTQANVARGMTVRELCEAIMLRSDNAAANLLMRRSGGP -AGLTAFLRSIGDRVTRIDTYEGHLTDH--PLPADSSTPRAVTETVRRILCGPVLPIAGRR -VWEGWMAGNIVGRARLRASFPANWIAGDRTGTGD-GICNDFAFARRPGIAPLLLSAYYTA -PGSELPDQEAVLRAVSRLVV--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001411FFDD --dALRSNIQQIVSSKNAIVGVSIIGNNGKDTM-SLHGDRRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIEIRKDELLPWSPLRDENPNGGFTIEKLIQYSVSNSDNTACDVLIRLIGTP -KTVEEYFKKNNIQDIQITYNEEEMQSKWENMFQNWTTPKAASETLKMFYENNLLSKSSYD -FFWKTNIETTTGENRIKGQLPKGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE -SKENFDTNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0B6D7N7_9GAMM ---EISNRLHNLEKQYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVIGAILKQSM -TDNNLLNEEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-ESDNTATNLLIEKLGGL -NNLNKFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLESDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKNAKPNSKIIREVTKILLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Haloactinobacterium sp. F-300 TaxID=2666133 RepID=UPI0012D5039F -------ALVRLEEESGVRIGAVGI--SSAARV-AHRAEEAFPMCSLFKVLAVASLLRERA -YDDAYWAEPIPFGPADLVEDSPVTSATTTWAMSPTALADAALRFSDNTAGNLLLAELGGP -EAITTFAADLGAASTRLDRWEPELNEATPGDLRDTSTPSDIALLYRALLLEDRAGVLTGA -RLRDWMLRNTTSAARIRAGLDGDVELADKTGAGSYGVVNDAGMLWSAGSDPVTLVILTRT -DDPAAANDNEVVAEATRIIMS-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X3I7_9BACT ---RLQERLNNLDSSAQGNVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD -EGKLSLNQTVTITREQFAPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP -EQVTAILGRMSLRNIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLVKLQSRQLLSEDSTA -LLLKIMTDSPTGQKRLKAGLPQGWSIAHKTGTGEDVATNDVGLISSPTGKHIAVAVFIAG -SKAPLEQRESVMSAVASAVIQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium aquifrigidense TaxID=558021 RepID=A0A543EL48_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLDAVD -KRKLSLDQKIKLDSSNLLQWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLKLLGGP -QTVQKFMDSKGVKGFQIKYNEEEMHKDWNVQYQNYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMKVLWSTSTGMNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] class A beta-lactamase n=1 Tax=Oceanibium sediminis TaxID=2026339 RepID=UPI000DD322E4 ---AVGAAIERVATGLAGRIGFAAQEIGGDDVI-AFNGDETFVMASTYKVAIAAAVLDRVD -RGELSLDQMVDVTPDMMMIDAALSDTFVHPGLSVANLIEIMITESDNTATDISMGLAGGP -AAVTEYLRRLEITDFRVDRTTGEIIGDFEADPRDQSTPLAMLQLLLAIDSGAATSAESRD -FLINVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAVAVFTKS -SATSEADRDRAIAEVTRSLFDYf ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium nitrogenifigens TaxID=378548 RepID=F1Z6G2_9SPHN ------ARLSALETRAGGRLGAFVLDSRSGRGF-GWRGDERFALCSTFKLSLAALVLREIE -AGRLDGAETLYYSIIDVLPASPRTGDAAGKGLPVLALAQAALETSDNLAANLLLDRLGGP -EALTAFWRQVGDTDSRLDRHEISLNRVYAGDVRDTTTPMAMARTVSALTTGTVLTSASRA -QLWGWMKACGTGLARLRAGLPAQWQGGDKTGTFAPAHVNDIALVLAPDHAPIAVTAYYEP -AGAIAPASETVLAEVARIAAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Leucobacter musarum TaxID=1930747 RepID=UPI0006A77FB7 --rTLSQRLNRLQGQYGARIGLFALDTLTDQVV-GFNEDHRFGYASSIKALLAAFFLERVT ---GESRGEQVTWTQEQVDDYAPVTGEHVGERMSVQELAEATVRTSDNLAFNLVLEKLGGP -DAFQQWLRDQGDQATEFASYEPFVNDIVDGDTANTSTPASMTSTLAQVVTSLGRESADQD -LLVEWMSGNATGDTLLRAGVPAGWTVADKSGGAA-GMRNDIAVITQHGQDPVIVSVLTTK -RDPKEKYDDQLLADVAEALF--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=F4Y5N6_KLEOX ------------------------------------------------------------- ------GNKRLEIKKADLVVWSPITEKHLQSGMTLAELSAAALQYSDNTAMNKIIGYLGGP -EKVTAFAQSIGDVTFRLDRMEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIGVIWPENHAPLVLVTYFTQ ------------------------ ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Syntrophus sp. PtaB.Bin001 TaxID=1811710 RepID=A0A1V4Y0Q9_9DELT ---RLEREMKRLASQAGGTVGISALHIESGQHF-SFNGKERFPMASVYKIPIAVRLLNRVD -RGEVSLDRTVALSTCDFHPGSGLVQKFKNKKYTVRELLELMLLVSDNTASDALLKLAGGP -EAVTSFMKTLGINDIQVSRSTLNMLACFFSDIRDTATPEAMTCLIAKVHSGTALKPESAS -MLLEIMERCRTGKSRIRRMIPPGMAVADKTGTIGKGMVNDAAIMTLPAEGHVALTIFIKT -SEQTVSQQEQAMAQMARYLYDYf ->[subseq from] Beta-lactamase n=1 Tax=Muricauda sp. SM1704 TaxID=2292706 RepID=A0A371JRV6_9FLAO ---TLKLKIEDVINSKKAVVGVAINGMEPKDTL-SINGQGHFPMQSVFKFPIALTILSEID -KGNLSLDQKIEIKKSELLPWSPIREKHPEGGFTIAEIIEYTVALSDNVGCDALLRLLGEP -QAVENYFSSLGFKDFAVKINEETMQGNWDLQFLNWTTPKEANKILAAFYENKLLSKESYD -FIWNIMKGTKTGKNRLRGQLPEETIVAHKTGWSGTAAVNNIGIVFLPNGEYFAISVFVSE -SPEDFETNEKIIADISKAAWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter psychrophilus TaxID=651661 RepID=A0A1T5FD77_9BACT ---DFKSQLESITKQVDGITGVAIEDLQRNETT-ILNPDHKFPMLSSFKFPIAMAVLDQID -KGKLSLTQKYHLTKEDVQLYSPLRDKYPDGNLTIADLLTSMVSLSDNIACDILFKLAGGT -KPVQDYVHSLGVKDIAIVANEEQMGQDWNVQYTNWCKPGAMLQLLEIFYKGKNLSKPSHE -FLSKIMIDGPTGLNRIKGQLPKDAVVAHKTGTSGTAAVNDVGIVKMPDGRSFAIVLFVSN -STADLKAIELVMAQVSKAAFDHy ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium hagamense TaxID=395935 RepID=A0A511YJ47_9FLAO ----LDSKINSIIQGKKATVGVSVLGFENGFKY-SKNGEKKLPMQSVFKFHIAAAVLDRVD -KGKLSLDQKVSLNAANLMPWSPLRDKYPNGSVPLSEIIEYTVAKSDNNGCDILLKLLGGT -GTVQKFMDSKGVKGFQIKYNEADMHQDWNAQYKNYSTAVSATDVLKKFYDGKLLSEKSTA -YLMKVMLSTSTGMNKLIAQLPKDTPAARKTGASGTGAENEIAIITLPDGKHYAIAVFVSN -SAETQEVNCKMISDISKLVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Nocardioides lianchengensis TaxID=1045774 RepID=A0A1G6V7G0_9ACTN ------------------------------------------------------------- -----------------------------EPGASLREDLRRAVSDSDNDAANRLIDRLGGP -ASVTRFARTLGDDVTRLDRREPDLNSAVPGDPRDTTSPRAIAATYRTLVLGDALPRGARD -LLTDLLVGSTTGAERIRAGLPEDWWVGDKTGTGGYGSTHDVAVVRPPGGEAFVLAVYTSY -DDPAAEPDQDLVAAVARLVVS-- ->[subseq from] Extended-spectrum class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9MB49_9FLAO ----LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD -FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGKPAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=D0UY02_ACIPI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTF-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase (Fragment) n=19 Tax=Bacteria TaxID=2 RepID=A0A345N8P8_PRORE ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter terrae TaxID=405671 RepID=A0A1G7PYT8_9SPHI ----LNAKIQQIVASKHAKVGIAIKGPGIKDTL-FINGDQHFPLQSVFKFHVALAILSQVD -QGKFSMSQKINITKKDLLPYSPIRDRYPNGVLPLSEILAYTVSQSDNIGCDILLRMIGGP -EFVEKYCNSIGIQDVSIKINEEEQQSNWNAQFKNWTTPKAANEILELFYMNNLLSKKSYQ -FIWKVMRETKTGEGRLRGQLPTKTIVAHKTGSSGTAAVNDIGVVFLPAGAHYFISVFVTE -STENAATNEKIIADINKAAWDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. JC507 TaxID=1978493 RepID=UPI0010A88ECF --sALDQKINSIIKDKKATVGVSVLSFESNFKY-SKNGDKKLPLLSVFKFHLASTVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIIKYTVAQSDNNTCDFLLRLIGGP -KVVQQFMDSKGVKDLQIKYTEDDMHKDWKNQYGNESSTNSTVVLLKKFYDGKLLSKKSTD -FLMQIMLATTTGTNKIVEQLPKRTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAIFVSN -STETERVNTRMVSDISKIVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A4Q3EUL5_9SPHI --aPLRAALQQVADTTDGRLGIALWQVEAGDTI-TLGNSQHYPMQSTYKLPLALYILHLAD -EGKLKLDEPIYIPASTLDTWSPMLKDHPNQGLSIQELLAYTIGLSDNNACDILFRQAGGT -QPVHKYIHSLGIQDMAIAATEAEMAKGWQVQYTNWCTPMAMAQLLHRLYNGQLLGKASTA -LLMDMMANSLNSASRIKGMLPPGTPVAHKTGTSNTGAVNDVGIITLPNGKHLIVSVYVSN -FTGGTARGEAIIAVVSRLAYNYf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A516TQ62_PSEAI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=8 Tax=Bacteria TaxID=2 RepID=A0A0C4XPR7_9BACT ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=Q9AMJ6_PSEAI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Class A extended-spectrum beta-lactamase VEB-23 n=1 Tax=Enterobacter cloacae TaxID=550 RepID=A0A650A9A9_ENTCL ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=33 Tax=Bacteria TaxID=2 RepID=Q7BVU7_ECOLX ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X222_9BACT --sDLTGQIKQIAKTVGGRVGVAATILETGETV-SLNAKDRYPMQSVYKLPIGMTVLSQID -AGQLNLSERLRIEKENVLKTSRILEKFPDGTQTIEELLRLMVSESDNTASDALLRLVGGP -EAVMKFLNKNEIFGIEIANYEKEFAADWRVQYKNRAAPKAAIELLRALHESRGLSAQSQA -LLLKYMTDSPTGPRRLKGLLPEDAQVAHKTGTSGTAATNDIGIVTLPDGRHLAIAVFVSD -SPADETIREETIARIARAVWDYw ->[subseq from] class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI00015D78FC ---QVTNDIQNIEKKHGGKIGVYTINRNDWSNF-AVNASFYFPICSTYKFLVVGAILKQSM -TDNKLLNQKIKISKNQIVEYSPITRRHINQTMTVKQLCQASMQ-GDNTATNILIEKLGGL -KNLNKFILSLADHATKVANLEPKVNHVSLTTNENKTTPKIMARDINKLAFDDILDKKHRL -MFKQWLIASNTSNNHIAVEVPDEWEVGDKTGTCQYGTTNDVAIIWPDDNRAVIMAIFYTQ -SQKNAKPNSKIVREVTKILLN-- ->[subseq from] Beta-lactamase n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A1B1LRY6_VIBPH ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A3RJX8_ECOLX ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=1 Tax=Proteus mirabilis TaxID=584 RepID=A1YTM5_PROMI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=3 Tax=Enterobacterales TaxID=91347 RepID=B1P2H7_PROMI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=2 Tax=Pedobacter TaxID=84567 RepID=A0A4R8P4I3_9SPHI ----LNAKIQEIIASKHAKVGIAIKGPNERDAL-SINGNEHFPLQSVFKFHIALAVLSQVD -KGKFSLSQKIKISKKDLLPYSPIRDRYPNGVLPLSEILAYTVSQSDNVGCDILLRMIGGP -EFVEKYCKSVGIHDVSIKINEEEQQGNWNSQFKNWTTPKAANNILELFYMNNLLSKKSHH -FIWKVMRETKTGAHRLRGLLPKNTLIAHKTGSSGTAAVNDIGIVFLPNGSYYFISVFVTE -STENEATNEKIIADINKEAWEYf ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=A0A4Q3FIC0_9RHIZ ---KLDKGIEGIEQAAKGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGTFKLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP -QVVTKMLRDGGIQGMSVDRYERQFQPNALKDKRDASTPEASAQFLEAFAKGNWLRPAHAA -LLTRIITETKVGADRIKAGLPEGSRLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAKEREAALAEVARLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3B8VWB4_9PORP --qNLQQKIDSIVVGKQAEIGVAIRNLDTGETL-GLHLDERFPMQSVFKFHLALQVLNEVD -KGNLDLNDMIVLQPTDLLEWSPMRDAYKAGEINIVTLLDLSVKRSDNNACDILLRQTGGP -VALNNYIHSLGIDSVNIVYDEATMHQAWDNQYENYTTPRAMADLLTLFAERKVLANNTRF -YLWNAMSNLTTGSGRLRKYLPEEALLVNKTGTSGAGATNDAGVIVMPNDPLVVVAVFVKD -STEPNEVNEEIIAQIAREVYNHy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium shandongense TaxID=1493872 RepID=A0A3G6MV88_9FLAO --sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD -QGKLSLDHKILLDKTNLLEWSPLRDKYQQGNVPLSEILEYTVAKSDNNGCDIMLKLLGGT -ETVQKFMNSKGVKGFQIKFNEADMHKDWNAQYQNYSTAASATEVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAVVTLPNGKHYAIAVFVSN -STETDAVNCKMISDISKSAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Cryobacterium sp. Y82 TaxID=2045017 RepID=UPI000CE3A7B4 ---AFNRRIEDLEMQSGVTIAVTAVNLGTNRRV-QHRSTDLFPMCSLFKVIAVGALVSERG -YDEQYWNTPIPFTAADIVVNSPVASKLTTLTMTPDEMADAALRFSDNTAGNLLLREIGGP -KTIARVVGSFGATATRLDRIEPELNEGLPDDPRDTTTADDMVAVLRALLVDGGAGQLARS -KLHDWMLRNSTSSTRARAGLTGSYELADKTGAGGYGIVNDAGILWQDDTDPIALCILTRT -NDPNAKGNNEVIADTTRLLVS-- ->[subseq from] EXTENDED-SPECTRUM BETA-LACTAMASE PER-1 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI000011119C ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSQTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A3A0VQL2_STAGA ------DSIEDLETTYDTTIGVYGINTQNGNEL-SHHADERFGFASTYKAIASGILLKQLT ---PQAMNQRVTIEKSDIVTYSPITEKYIGKTMTLRQLIEASMLKSDNTANNKVIQALGGV -NAFKSELRHLGDSVSEPQRLEPELNDYDPKRIADTTTPRAAATTLNRILTHPDMAKGNLQ -FMKQLMIENETGDTLIKAGANEEDIVGDKSGQGTYATRNDLAFIYPKGQQPIVLAIYTKQ -SDKNAKPNDEVIAKTAKIAIN-- ->[subseq from] Beta-lactamase n=1 Tax=Deltaproteobacteria bacterium ADurb.Bin026 TaxID=1852864 RepID=A0A1V6IDQ5_9DELT ---SLKQEIQKIISSKNATIGVAVLGNNGQDVF-SINGERHFPMQSVFKFHIGLAMLSEID -RGNFKLNQKIKIKKSELLPWSPIREKYPEGALSIAEILEYTISQSDNVGCDILLKILGGP -NFVENYIKASGVDNISIKINEEVMQNNWDRQFENWTTPLAANQILELFFLNELLSPSSYD -FLWKIMKETATGKKRLKGNLPVGTVVAHKTGWSGTAAVNDIGIVFLPDNNNFFISVFITD -SKENAEVNEKIIADISKATWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Luteibacter jiangsuensis TaxID=637577 RepID=UPI00141E7FBA ---HLRDTLAQLAERAPGTLGVTVVDMETHERT-RINADRGYPMMSVFKAPVAAAVLAEVD -AGKIALDQEVTIGRKDVVGGSPSIGAHFAGGFTVERLLVAAVSESDNTAVDALIRLLGGP -AVVTRYLRDHGIDGMRVDLSEGDVSHAFMVDVRNTTTPDAAADFLEKLWRGKLLSAASTQ -RLLRLMYDQTV-PNRLRAGLPPGVRFADKCGTSYTAAFNDIGIVTWPDGHTVIVAAFLTG -SRADAKTRNALFADIARAI---- ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=A0A0G3XED2_9SPHN ---------NIVEETANGTLGVAVFDTGTGRIW-GHNDYARFPQLSSFKLSLAALVLHLDE -TGTLDAGEHISWEASELLDYAPFAKDRLEQGATLRELAEATQTLSDNTAANVLLRRLGGP -ERLTSFWRAIGDETSRLDRTEPALNDVPPGEIRDTTTPAASARTLAKLVYGDVLGDVART -TLKTWMAETRTGMRRVRAGLPPEWPAGDKTGTSFGSVYVDVGYVEPAGRAPLTFATFFRA -ARQHDPRAEGALAETGRIIAR-- ->[subseq from] Class A extended-spectrum beta-lactamase CSP-1 n=2 Tax=Capnocytophaga sputigena TaxID=1019 RepID=D5HKL4_CAPSP --qNLKRDITKIIQGKNALVAVSVMNSKGKTEV-NINGNKKVPMLSVFKFHIALAVLDLVD -RGILDLEQNIFVKKSELLEWSPIRDKYPNGNIPLREIIEHTVSQSDNNGCDILLRLIGGV -DTVQKFIESKGIKDFAIKYNEEEMNKNGKSIYSNYTTANASSRLLQKFYNGEIISESSRD -FLFRIMYETSTGADRLISLLPPDVIVAHKTGTSGQAATNDVGIIILPDDEYYTISVFVIN -SKENTSTNEKIIADISKTVWDYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CF365 TaxID=1500282 RepID=UPI0005547FF0 ----LEQKISSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAILNHVD -QGKLSLDQKIKLDQSNLLEWSPLRDQYPGGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEHf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A2W6TAA3_9FLAO ----LDQKINSIIKDKKATVGVSVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKIVLDKSNLLEWSPLRDKYPNGGVPLSEVLEMTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTMNSATDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKLIEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN -SMETDAVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium geocarposphaerae TaxID=1416776 RepID=A0A2M9C8T0_9FLAO ----LDQKINSIIKDKKATVGVSVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKIVLDKSNLLEWSPLRDKYPNGGVPLSEVLEMTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTMNSATDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKLIEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN -SMETDAVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter caeni TaxID=288992 RepID=A0A1M4VLZ6_9SPHI ---PLQQKLDSIVRTKKADVGFSVLYLENQKVV-SVNGDKHYPMQSVYKFHLALAVLNQVD -QGKFSIDQKILVKPSDLLQWSPIRDKYPNGNLPLSEILKYTVSESDNNGCDILFRLIGGT -GKAHQFIKKQGIKEISITGTEEEMHKDDQVQFRNWTTPKAANQLLKKFWEGKVLKKATGD -FLMKIMEETVTGPGKIKGLLPQGTVVAHKTGNSGVNGSNDIGIVTLPNGKKMLISAFVSM -TKEDDKEVDKIIAELAKAAFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=UPI00069E2038 ---------NIVEETANGTLGVAVFDTGTGRIW-GHNDYARFPQLSSFKLSLAALVLHLDE -TGTLDAGEHISWEASELLDYAPFAKDRLEQGATLRELAEATQTLSDNTAANVLLRRLGGP -ERLTSFWRAIGDETSRLDRTEPALNDVPPGEIRDTTTPAASARTLAKLVYGDVLGDVART -TLKTWMAETRTGMRRVRAGLPPEWPAGDKTGTSFGSVYVDVGYVEPAGRAPLTFATFFRA -ARQHDPRAEGALAETGRIIAR-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A0Q6GMH0_9NOCA --eDFSTELQAVEDRYDVTVGVSLLDTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP ---QDARDDIVRWSAADIERYSPVTTARLDTGLTAAELAEAAVRASDNTATNLVFDRIGGP -AQLDAALSRLGDDVTDIVDVEPGLNTVEPDSTANTTTADTFTANLAALRGDGSSTDADAA -TLVEWMSENATGDALVRAGAPSGWTVADKSGGAG-GVRNDIAVVTPPGRPPLVLTVLTRK -NDPSAPYEDAAVSESAAVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Koribacter versatilis (strain Ellin345) TaxID=204669 RepID=Q1IR91_KORVE ----LTKTVKTAAHPANGKVGVSAKVLDSSQTI-SFHGNKNFPMQSVYKLPIAIFTLRRVQ -EGKIKLDQVVKVDEDDLIPNSPLRDKHPRGGFTIEDLLRRAIVDSDGSASDVLLKQIGGT -REVRRYLKSQKIKGIRVQHTEEQLIENTHLQYSDSAKPDAMVDLLERLQQGKLLDTENTA -RLVGWMKETDTGKDRIRAKLPSG-TVADKTGSSGTKATNDVALVTLPNGNHFAIAIFVTD -SKADTKTRNLVIANIAHEVWSCw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0P0GGT1_KLEPN --------------------------------------------CSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLRDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011EF0E3B ----LRKHIQEIVASKNATVGVCLVSDDGDDTL-SIHGSRRFPLQSVFKYHIALAMLSQID -QGKFSLDQKVTIEKADLIPYSPIRDKYPNGALKMSEILDYTVSQSDNVGCDLLLKLLGGP -QVVEKYIKGNAINDVSIVINEQTQQSNWDLQFQNWTTPKASVAVLQKFFINKLLSPKSYD -FLWQVMKGTQTGKARLRGKLPEKTIVAHKTGSSGTAAVNDMGIVFLPNGRHFYISVFVTD -SKENAGANEKIIADVAKAAWEYf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000FD77750 -----------------------------------------------FKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPWIRSVLPAGWFIADKTGAGERGAR---------------------- ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. Tr-659 TaxID=2608340 RepID=UPI00141F68CE --sALEQKISSILKNKKATVGISVSGFENGFTY-NRDADKKLPMQSVFKFHIAAAVLNAVD -HGKLSLDQKIPLNKSNLLEWSPLRDKYPDGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QVVQKFTDSKGVKDFQIKYNEEEMHKAWNIQYENFSTTKSAVDVMRKFYDGKLLSKKSTN -YLMKVMLSTSTGLNKIIEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYAIAVFVSN -SMETEADNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Clavibacter michiganensis subsp. phaseoli TaxID=1734031 RepID=A0A399THM1_9MICO ------------EERFGARLGVHAVDTGTGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADILSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRAEPDLNQAIPGDDRDTTTPRAAAALLRAYALGDPLDADERA -LFTGWLKATQTGATLGRAELPADWTVGDKSGLGAYASRGDVAVI---------------- ------------------------ ->[subseq from] Class A beta-lactamase n=3 Tax=Cryobacterium TaxID=69578 RepID=A0A5F0D316_9MICO ---AFNRRIEDLEMQSGVTIAVTAVNLGTNRRV-QHRSTDLFPMCSLFKVIAVGALVSERG -YDEQYWNTPIPFTAADIVVNSPVASKLTTLTMTPDEMADAALRFSDNTAGNLLLREIGGP -KTIARVVGSFGATATRLDRIEPELNEGLPDDPRDTTTADDMVAVLRALLVDGGAGQLARS -KLHDWMLRNSTSSTRARAGLTGSYELADKTGAGGYGIVNDAGILWQDDTDPIALCILTRT -NDPNAKGNNDVIADTTRLLVS-- ->[subseq from] Beta-lactamase n=1 Tax=Anditalea andensis TaxID=1048983 RepID=A0A074L5V1_9BACT ----LLKEIERIVSDKDAIVGVSIIANNGKDLV-SLNGDKHFPMQSVFKFHIALAVLSEID -KGKLSLNQEIVLSKEDLLPWSPLRDENPDGGFTIAKLIQYSISQSDNTACDVLIRVIGIP -YTVEEYIKKNGIQDIGITFNEEDMQTKWENMFQNWTTPKAASMTLKRFYDNDLLTKESYD -FIWDVMKDTTTGKNRIKGQLPEETIVAHKTGWSGTAAVNNIGIVFFPSGAHFILSVFVTE -SKENFETNEKIISEIAKATYDFy ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NI49_9BACT --qRLAQELESIAKLAKGKVGICALHLESGKQV-SLNLQERFPMASTVKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQNRVKALGIQGMSVDRTIIQLLAKLKTDPRDTSTPEAMVNLLTQIYRGTALKPESRA -LLLGVMERCRGGAARLKSYLPPNTVIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPLAEREQVIAHSARSIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139WVI3_9CYAN --------------AAQGNVGIGVLDLSTGKSW-FRNGKQRFPMQSVYKLPIAIATLKRVD -EGKFALNQPITVTRQELAPWSPITKEFKGNSFTVQNLLERSVGISDNTAADVLVRLVGGT -GQVNAILGRLKIRDVRVDRLERQLQSRYLVDPRDTATPEGIVDLLVKLQSNQLLSQKSTA -LLLKIMTDSPTGAKRLKAGLPNNWSIAHKTGSGPGTATNDVGIVSSPNGKRVAIAVFIAG -SKAPVEAREKVMSNVASAVVK-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Francisella TaxID=2610885 RepID=UPI0011B35BBA ---QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL -SNLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL -LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ -SQENAKPNSKIIREITKILLD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium aurantiacum TaxID=2116499 RepID=UPI000D11B403 --qDLRNKINTITSTKNATVGISVKGIEDKDTL-SINGNKETPLMSVFKFHIALAVLHRVD -EGKLKLNQKFFIKKEVLLPWSPIREEYPDGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -DSVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPAGTEVAHRTGISSRAAMNDVGIVKLPNGKHFILSVYLKN -INEEMADTEKIIADISNAVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Aeromonas caviae TaxID=648 RepID=D7P3C9_AERCA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=25 Tax=Proteobacteria TaxID=1224 RepID=BLE1_PSEAI ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Larkinella arboricola TaxID=643671 RepID=A0A327X7X7_9BACT --qRLNQELERIAKLAKGKVGLCAVHLESGQRI-SLNVQEKFPMASTVKVAIAVELFNKIE -KGELSLRTMVELKPSDLHPGSGTLETLFAKPLSVENLLELMMVISDNSATDILLNLVGGV -EPVRARLKTLGIEGMSVDRTIVQLIAKLEQDPRDTSTPEAMVNLLTQIYQAKALKPENRD -LLLAVMERCRGGLARIKGFLPPETVVAHKTGSLNSSATDDVGIITLPGDGHIAIAVFITS -SAQPLAEREQTIAHLSRTVYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1Z1E9_ECOLX ------------------------------------------------------------- --EPNLVNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTTDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SFT5_9BACT ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTL---- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Erythromicrobium ramosum TaxID=35811 RepID=UPI0013267C31 ---QLAAELRIIEAAGDGTLGVELFDTVSGMSV-GLNRDRRFGHASSFKFSLAALLLQRHA -AGQIDADKRVTWTEADMLEYAPFTRERIGAGATLRELARATQTTSDNPAANILLRNLGGP -AGLTAFWRSMGDEVSRVDRYEPEMNIVPPAEFRDTATPAAMARNVAKIIYGDVLPEAERA -ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGEGNYIDIGFAEGPKGPPITFACYFRA -RQAEAARAELTLSRVGRII---- ->[subseq from] Beta-lactamase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8QA90_9BACT --eSLRDKIYQIASAKNATVGVSIMGSNGNDTL-SLNGENRFPMQSVFKFHIALAVLSQID -QGRLSLDQKIKIQKKDLLPHSPLREKYPNGALPLSEVLSYTVSSSDNVGCDALLRLLGGP -QEVERYFVRNNFQDISIKINEEVMQNNWDLQFQNWTTPNAASKVLKSYYHEKLLSQKSHD -FVWKEMRETETGKNRLKGQLPKGTVVAHKTGSSGTAAVNDIGVVFLPNGEYYFISVFASN -SNEDLPTNEKIIADISKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI00138F8355 --eDFSTELQAVEDRYDVTVGVSLLDTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP ---QDARDDIVRWSAADIERYSPVTTARLDTGLTAAELAEAAVRASDNTATNLVFDRIGGP -AQLDAALSRLGDDVTDIVDVEPGLNTVEPDSTANTTTADTFTANLAALRGDGSSTDADAA -TLVEWMSENATGDALVRAGAPSGWTVADKSGGAG-GVRNDIAVVTPPGRPPLVLTVLTRK -NDPSAPYEDAAVSESAAVVLN-- ->[subseq from] Class A beta-lactamase n=1 Tax=Shewanella maritima TaxID=2520507 RepID=A0A411PDM4_9GAMM ---SLNTDIKSLLDSKQATVGVSIWDQNANPIV-AINADNQLPMQSVFKFHLAAAVLHQVD -QGKWSLADKITITPDDLDNWSPIRKKYPTGALTLAQVIKYTVAVSDNVGCDVLIGMLGGP -KVLEQYLHQAGIKDIAVKYNEEMMQQVWQRQFDNWTTANGANQALSKLYDEQLLSATSHR -FLWDVMKSSKTGKNKIRAGVRQGTIVAHKTGYSGKHAHNDIGIVFLPNGSHYYISILVSD -SRESSDDSQKIIADISKLAWMHf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR485 TaxID=1500294 RepID=UPI0006481857 ----LEQKINSILKNKKATVGISVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIVLNKSNLLEWSPLRDKYPDGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QPVQRFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVNVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVEQLPKSTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISKEVWEYf ->[subseq from] Beta-lactamase class A n=2 Tax=Parapedobacter luteus TaxID=623280 RepID=A0A1T5BWG6_9SPHI ---TLRRQIAQIADSKDAVVGVAITGRDGQDTL-SVYGSRRFPMQSVFKFPIAVAMLSEVD -KGTFSLDQKITIKKSELLPYSPIRETYPEGALTIAEILRYTVSLSDNVGCDVLLRLLGSP -QVVERYFHERSFKEISIKINEEIMQGDWEAQFRNWTTPNEANRILQACYEDNLLSPESYD -FLWGLMKTTETGKNRLKGQLPEGTVVAHKTGWSGTAAVNNIGVVFLPDGNYFYISVFVTD -SKEDLETNERIIADIAKAAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus sp. NAM3COL9 TaxID=1667172 RepID=A0A0Q9Y1X5_9STAP -----ANEFDKIEKDNNTTVGVYGINTENGKKV-RHNANERFAFASTFKATASGVLLNNYS ---EKDLNKKITINEADIVEYSPVTENYIGKQMTLKDLIKASMLQSDNTANNKIMKEIGGV -KAFKHELKQLGDNISNPQRLEPELNLYNPNSTADTTTPRAAAEILNTLLTSSQISDGNLD -LLKQVMIENETGDSLIKAGAADNYIVGDKSGQGTYATRNDLAFIYPNKHKPIILAIYTKQ -DDKDGQPDDKVIADAAKEAIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012F7F425 --qRLEQELESIAKLAKGKVGVCALHLESGKQI-SLNVQERFPMASTVKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQNRVKALGIKGMSVDRTIIQLLAKLITDPRDTSTPEAMVNLLAQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPTAEREQVIAHSARSIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. StRB126 TaxID=878220 RepID=A0A077KL18_9FLAO --qDLRSKINTIISTKNATVGVSLKGIEDKDTL-SINGNKAMPMLSIFKFHIALAVLNQID -KGKLKLDQKFLIKKEELLPWSPIREEYPAGNLTLDQLLRYTVSHSDNNGCDILLKMVGGA -PAVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGFPAGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSVYLKN -SNEEMKDTEKIIADIGNAVWEYy ->[subseq from] Class A beta-lactamase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4U6D890_9BACT ---RLDHELGRIAKLAKGKVGVSAVHLETGKHI-SLNLKELFPMASTIKVAIAVQLFTKIE -KGELSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -KAVQERMNALGIKGMSIDRTIIQLIARLQKDPRDTSSPEAMVNLLTQIYNGMALKPESRE -LLLGVMERCRGGVARLKGYLPTGTVIAHKTGSLNASATDDVGIITLPDGGHVAIAIFVAE -SGAELAEREQTIAHISRSIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Klenkia soli TaxID=1052260 RepID=UPI000B83509A ---DVSAELAALEQEYDVRIGVSAVDTGTGTRV-EHRADERFGYASTLKAFAAGVFLREVP ---SADRARLVTWSQTDVDAYAPVTGAAVATGLTAAELAEAAVRQSDNLALNLVLDLLGGP -AGLDAALADLGDTTTDVVHEEPALNDVDPASTADTTTPAAFTDGLRALLAPGALTDADRS -TLLSWMSGNATGDTLVRAGAPAGWVVADKSGGAG-GIRNDIAVVTPPGRDPVLVTVLTEE -LDPTAAYEDAVVARTAAAVL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UHJ9_ACIBA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHNSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASR- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9D4_ECOLX ----------------------------------------------TSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNHI------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas ginsengisoli TaxID=336566 RepID=A0A0R0DGQ7_9GAMM ----LQHEAQRLVAMLPGEVGVSMLHLQSGRAV-HVNGERAFPLASVMKVPVAVHILTLVD -EGKLRLDQNVVIGPNDIYPGGPMQIH-LTPGISVRDLLHMMITVSDNNATDMLVKLGGGT -DAVTQRMRQLGINDVRIDRYIWELLAAWNRDPRDSGTTTAMAQLLASVWKGQVLSDNSTA -VLKAIMGQTRTGAGRLRGVLPPDTPVAHKTGTVGD-VINDVGVITLPDGKGEVIVAVLME -STADTAQRERVIANLARAAHDYf ->[subseq from] Beta-lactamase n=1 Tax=Klenkia soli TaxID=1052260 RepID=A0A1H0UJ68_9ACTN ---DVSAELAALEQEYDVRIGVSAVDTGTGTRV-EHRADERFGYASTLKAFAAGVFLREVP ---SADRARLVTWSQTDVDAYAPVTGAAVATGLTAAELAEAAVRQSDNLALNLVLDLLGGP -AGLDAALADLGDTTTDVVHEEPALNDVDPASTADTTTPAAFTDGLRALLAPGALTDADRS -TLLSWMSGNATGDTLVRAGAPAGWVVADKSGGAG-GIRNDIAVVTPPGRDPVLVTVLTEE -LDPTAAYEDAVVARTAAAVL--- ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. CH25 TaxID=713559 RepID=A0A4Q1FNU4_9FLAO --sDLEQKINSITKGKQATIGVSVLGFENNFKY-SQNGDKKLPMMSVFKFHVACAALDLVD -KGRLSLDQKVFIKKSELYNWSPFRKKYPEGNITLSEVIDYTVALSDNNLCDILIDLVGGT -QTVQKYMDSKGVKDFQIKHSERGMANGWDSLYENYTTTNSTVQLLKKFYDGKLLSKKSTD -YLMNIMLGTQTGTNKLVEQLPKGTPTAHKTGSSSTIAENDMGIITLPNGKHYAITVYVSN -SKESEAENCKIISNISKAVWDNf ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8Z1G4_9BACT --qRLNQELERIAALAKGQVGICALHLESGKQV-SLNLQERFPMASTVKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -QAVQNRLKTLGIQGMSVDRTIIQLIARLKIDPRDTSTPDAMVNLLTQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPLAEREQTIAHAARSIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Filimonas sp. YR581 TaxID=2135469 RepID=A0A2U0ZQS5_9BACT ----LREKMAAVAARSGGVVGIAVTNLDTRDTF-TLNNEPVYPMQSVFKFPIAMAILHLID -GGKLAPEQKIFIGKNKMVKYSPLRDSFPAGNQTIAQLLQYSVSKSDNIACDLLIELAGGE -AAVNDYIHSLGVQQISIVASEAKMHANWNTQYKNWCAPSALVQLLDIMNQGKALSKTSND -FLWKLMLETTTGKKRLKALLPAGTEVAHKTGLSDTAATNDVGIILLPNGQKLAVAVFVMN -SKANEAVREATIAEVAKLAYDH- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. ERG5 TaxID=1381597 RepID=UPI00054BED58 ---RLTAEFARLAKQTDGTVGVAVQRVDGNART-TLNGGTNFPMASTFKIAVAGTILARID -KGELTLDQMIAVDPAVIVESEGIAEQTPHPGLSIHNLLELMLTRSDNTATDVLTALAGSP -VAVTAWVRKLGVTGQQIDADTAHIIYSFNDDPRDSSTPEAMLDLLLKIQSGKALSATSTK -ALLDIMERCHTGEARLKGRLPLGTVVAHKTGTLMS-IANDVGLVTLPDGSKFAIAVFVKG -DTKGTAVQERVIADIARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Francisella marina TaxID=2249302 RepID=A0A5C2BWA5_9GAMM ---QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL -SKLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL -LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ -SQENAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=M9TM58_9STAP -------DIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKKITLKKLIEATMLVSDNTANNKIIDELGGY -EQVKTRLIDLGDSTTHPSRKEPNLNYYSPKDKRDTSTPLAYGKTLKKLISDGNLSKANKD -FLLDLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK -DRKDGKPNDKIVS---------- ->[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-2 TaxID=2610886 RepID=UPI00123D0B7F ---QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL -SKLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL -LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ -SQENAKPNSKIIREVTKILLD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. xlx-214 TaxID=2654325 RepID=UPI0013D8A5D3 --nELKQKIQQIIWTKNVEVGVAISGNNNKDTL-SIHGNDRFPLQSVFKFHIAIAVLSEID -KGNLSFNQKIKIEKKDLIPYSPIRDKYPNGTLPLSKIIEYTVSQSDNVGCDLLLKLIGGP -KAVEEYFIKNGIKDVSIKINEEVQQANWDLQFENWTTPKAANEVLSTFYYAKLLSEKSYN -FLWKTMKGTETGKARLRGQLPENTIVAHKTGSSGTAAVNDIGIVFLPNGNHYFISIFLTK -SYENDETNEKIIADISKATWNYf ->[subseq from] Class A beta-lactamase n=2 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A0N0IXR3_9FLAO --eNLRKEIIRIINAKNATAGISIKNIENKDTL-SINGQMSMPMMSVFKFHIALAVLDQVD -KGKLKLHQKFLIKKEELLPWSPIRDEFPDGNLTLDQLLRYTVSHSDNNGCDILLRMMGGP -QTVQKFINKQGIKDITIKLDEEEMAKAWENLYVNVTTPEATTLLLEKFYKGKVLKKNTTD -YLYRIMVQTSRGLTWMKAGLPSGTELAHRTGISGRAAMNDVGIFKLPNGQHIILSVYLKN -ITEERADTEKIIADIAHAAYTHy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium shandongense TaxID=1493872 RepID=A0A3G6Q6Z2_9FLAO --sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD -QGKLSLDHKILLDKTNLLEWSPLRDKYQQGNVPLSEILEYTVAKSDNNGCDIMLKLLGGT -ETVQKFMNSKGMKGFQIKFNEADMHKDWNAQYQNYSTAASATEVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAVVTLPNGKHYAIAVFVSN -STETDAINCKMISDISKSAWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Eisenibacter elegans TaxID=997 RepID=UPI00041B25B4 ---NLETRLAEIVRGKQATVGVAILGLGGQDTL-LLNGYERLPMQSVFKFHIGIVMMAAID -EGRFTLDQPIKIRKRDLLPYSPIRDAHLKGALPVREILQYTIALSDNVGCDILLRLLGGP -AEVERYFHQRGFEALAIKINEETMQANWELQFQNWTTPLEATRVLAAFYNQPYLSPQSYD -TLWQIMTSTKTGQQRLKGQLPTGTAVAHKTGWSGTAATNDIGVISLPNGQPLFISVFVAD -SKEDNATNEAIIAQIAEAAWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Marimonas sp. GH1-19 TaxID=2545756 RepID=UPI0010F5CCA4 ----VGAAIERVATQLAGRIGFAAQEIGGGDVI-AFNGDEAFAMASTYKVAIAAAVLDRVD -KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP -AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD -FLIDVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SATSEADRDRAIAEVTRSLFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. XLW-1 TaxID=2610887 RepID=UPI00123E2AF4 ---QISNSLHNLEKQYGGKIGVYTINRNDNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TNKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL -SNLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL -LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ -SQENAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Agromyces sp. OV568 TaxID=2135465 RepID=A0A3E0I529_9MICO -hrRLSDAIAELERATSVTIGVTAIWHDSRRAF-RYRGDQRFPMCSVFKTLAAGALVQARG -YDEAYWAGPIPFTSADVVGDSTKLDTT-TWTATPEQMADAALRFSDNTAGNLLLRELGGP -QAVTAFARSLGATRTRLDRPEPEVNEATPGDERDTSTPDDIAFLLQKLLIDQGAGALTTA -RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT -DRADAPSNHDVLADVTRLVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Pelomonas sp. Root1217 TaxID=1736430 RepID=A0A0Q6TF25_9BURK ----TATDFVALERRVQGRIGFFAIDTGSGRVM-AHRADERFATASTFKILLAARVAQGVE -AGRWGWNDAVPLRASERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDSP -SGLTAWLRQQGDAVTRLDRFETELNENAPGDPRDTSTPRAFARTLQHLLLGPGLKRANQA -RLWADLQASRTGLQRLRAGVPASWRVIDKTGSGGRGAVNDVALVFPPSRSPWVVVAFQSD -SKASTDELSGVHAAAMRGLVRAw ->[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000B049B73 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. 2VB TaxID=2502204 RepID=UPI0010F9381C ----LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLNAID -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKLLSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Sulfitobacter sp. JL08 TaxID=2070369 RepID=A0A345RHD3_9RHOB ---SVGAAIEQIASGLAGRIGFAAQEIGGNEVI-AFNGDETFAMASTYKVAIAAAVLDRVD -RGELSLDQLVEVPPDMFVTVFALAETFPHPGLSVANLIEVMITESDNTTTDVSMELAGGA -AAVTEYLRNLGITDIRVDRTTREILMDFEADPRDHATPLAMLQLLLAIDGGTAMSPESRE -FLLGVMSRTRSGPGRLKGLMPKGTLVAHKTGTAG-GIANDVGYITLPDGRRFAIAVYTNS -NETPVADRDRAIAEIARMMFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Asaia bogorensis TaxID=91915 RepID=UPI0011BEC1D0 ----------RYEKLSGGRLGVHIFCPESGTAL-SWRGEERFRMCSSFKASLAACVLACCD -RDEDDLTRRIAFRESDFKEWAPVAARNRDAGLSLAALCAGAVTMSDNICANMLLRHIGGP -AALTRFWRDSGDEITRLDAYEPELNRPSANPDDNTTSPVAMARTLHRLIHGTLLHPNSAA -LLRSWMINCTTGTQRLRAGLPAHWVVGDKTGNNGKDIAADIAFASADAGKSVIIATYTAG -GTPDETQFRRVFHDIGALA---- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium phenoxybenzoativorans TaxID=1592790 RepID=UPI00087314E2 --dSLRAEFARFAAMTDGTVGIAVRRIGDDHAV-MLNGNTLFPMASTYKVAVAGAILAQVD -RGRVTLDTMIPVDRSMMVSGIADMMPHPGLSLSVYNLLELMLTRSDNSATDVLVKQAGGP -QAITGWLRSVGIRDQRVDGNTAQLLYAFAADPRDTSTPEAMLDLLTRIAQGRALKPDTTR -TLLDIMARCHTGQNRLKALLPPGTPVAHKTGTLN-GLANDVGVVTLPDGSAMAIAVFVMK -DSKGRDVRDRIMAEAARAAHDYy ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. WAO TaxID=406341 RepID=UPI0009F89F9B ---KLDAGIKSIEQAAKGRVGVALLDLRDRKSW-SHRGAEPFPLQSVFKLPLAIAVLQAVE -AGKLKLDQKITVTRNDLSLHSPLARAFKGERYTLRDLLTRSTGESDNTAADLLLRLIGGP -QVLTAMLKDGGVPGISVDRYERVFQPATLKDKRDAASPDASAAFLEALARGNWLREAHTA -LLDKIIVETKSGPQRIRAGLPQGARFAHKTGLGPNHATNDIGIVTLPDGRRFVIAVYLAG -SQASAEAREAAHAAVARLAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000AA34C63 ---TFAKDIEQIENEYNTKVGVYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. HKB08 TaxID=2502843 RepID=UPI001008ADB2 -----ASRLRIVEATANGTLGVAIYDTGSGALT-SYNGFARFPHCSSFKLSLAAFVLKLGT -DGGMDLSEKVDWDAAALLGHSPFTRERLATGATIRELAEAAQKQSDNTATNILLERIGGP -QGMTAFWRAIGDPTSRLDRYELELNNVPAGEIMDTTSADAMALTVGRLTHGDVLAEDDAA -TLRQWMVDTATGLDRVRAGLPPEWRAGDKTGTSLRSVYVDIGFVEPPDRAPLTFAAYYRA -NRKADPASLAVLADVGRVITQ-- ->[subseq from] Beta-lactamase class A n=2 Tax=Erythrobacteraceae TaxID=335929 RepID=A0A0P7YLZ1_9SPHN ----MQASLRLIEAKAGGTLGVEIHETATGVSV-GLNRDRRFGHCSSFKLSLAAMVLALDA -AGEIDANRRVTWTKGDLMPVSPFTERRLAEGATLLELAEYTQKYSDNAAANILLRELGGP -AALTGFWRSIGDGESRLDRYEPELNNVPVTEYRDTTTPAAMARTVAKLAYGDVMPEAERA -RLRQWMIDTPTGARRVRAGLPESWIAGDKTGTSIGSSYVDIGFARPPEHPPVTFAAYYRA -RETHDEGSEAALASVGEVI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium culicis TaxID=680127 RepID=A0A1H6HIX3_9FLAO ---RLEQKINSILKNKKATVAVSVLGFENGFTY-DKNADKKLPMQSVFKFHIAAAVLDAAD -KGKLSLDQKIKLDHSNLLEWSPLRDQYAGKEIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTRSAADVLKKFYDGKLLSKKSTD -YLMKVMQSTSTGLNKMVEQLPENTPVARKTGASGTGAENEIGIVTLPNGRHYALAVFVSN -STETDTVNCRMISDISKEVWEYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium mulctrae TaxID=2576777 RepID=UPI00111690BB ----LAHKVDSIVKDKKATVGVSVLGFEDGFKY-NKNATTKLPMLSVFKFHIAAAVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDDVNCKMISDISKAVWDHf ->[subseq from] Beta-lactamase n=1 Tax=Francisella sp. FSC1006 TaxID=1547445 RepID=A0A097ELS9_9GAMM ----TSNEIKKIEKEYGGKIGVYTINRNDWKNF-SHNASFYFPTCSTYKFLVVGAILKQSM -KNKELLSEKIKIVDNQIVGYSPITKKHSNKEMTIRQLCKASIN-NDNTATNLLIHKLGGL -KELRKFTLSLQDHATKVADLAPKISKVDLTTNLNKTTPKIMARDINKLAFNDVLDDRHQA -LFKKWLRESTSGDNRIAAEIPEDWTIGDKTGTCEYGTTNDVAIIWPDDSKPIAMSIFYTQ -PEKSAEPNSKVLRKVTEILFD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Rudanella sp. HX-22-17 TaxID=2614655 RepID=UPI001261E911 ----LRAEIQQIVADKKAVVGVSIIANDGKDTL-SLNGDRRCPLQSVFKLHIGLAVLSQVD -KGRFTLDQTVEVRKADLVPWSPLRDENPNGGFTIARLIQYAVSQSDNVACDVLIRLLGSP -KAVETYIKENGVEEIAIRFAEKEMQAEWDNMFQNWTTPKAASKTLQIFYDGKRLSKRSYD -FIWQTLRETGTGVNRLKGRLPAGTVVAHKTGSSGTAATNDIGLLFLPNGEFVIISVFVTD -SKENEATNEKLIADIAKATYDFy ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ADDD66 --kRLERELERISTLAKGKVGICALHLESGKQV-SLNVQERFPMASTIKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQKRVNALGIQGMSVDRTIIQLLAKLATDPRDTATPEAMVNLLAQIYRGTALKSESRA -LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLNNLATDDVGIITLPDEGHIAIAVFVGD -SPMPLAEREQVIAQSARAIYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. YR221 TaxID=1500293 RepID=A0A1W2DQD6_9FLAO --eRLRKEIQQIIASKNATVGISIKNIEDKDTL-SINGNSMMPMMSVFKFHIALAVLDQVD -KGKLKLNQKFFIKKEDLLPWSPIQEEFPNGNLTLDQLLKYTVSHSDNNGCDILLRILGGT -EPVQKFINQQGIKDFTIKVNEQQMS-NWDNLYLNVTTPIATTALLEKFYNGKVLKENTSQ -YLYRIMTETSRGLTWMKAGLPDHTELAHRTGISSRAAMNDVGIFKLPNGKHIILSVYLKN -ITEERTDTEKLIADIARATYNYy ->[subseq from] class A beta-lactamase n=1 Tax=Pelomonas sp. Root1217 TaxID=1736430 RepID=UPI00070D22E7 ----TATDFVALERRVQGRIGFFAIDTGSGRVM-AHRADERFATASTFKILLAARVAQGVE -AGRWGWNDAVPLRASERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCDSP -SGLTAWLRQQGDAVTRLDRFETELNENAPGDPRDTSTPRAFARTLQHLLLGPGLKRANQA -RLWADLQASRTGLQRLRAGVPASWRVIDKTGSGGRGAVNDVALVFPPSRSPWVVVAFQSD -SKASTDELSGVHAAAMRGLVRAw ->[subseq from] Beta-lactamase n=1 Tax=Syntrophaceae bacterium PtaB.Bin038 TaxID=1811716 RepID=A0A1V4X7F0_9DELT ----VAAEIGRIEKAARGTLGVAAVHLETGRKV-EYRAEEFFPMASTVKVPLAARILDMAD -RGQVGLATEIPVKKMEMNPEGPLAAIRWRPGRSIEELLEAMITRSDNTATDVLFRVAGGP -AAVEAWLKGMGLKDIRPARYIRELLRGYDADPRDQATPRAMLALLVKIRLADGVSAAVRS -TLIPMMERTETGTKRIRGRLPAGTVVGDKTGTLA-GTANDVGYVTLPGGGCIALVVFVKG -SEAAPAARETAIADTARLVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A521GD05_9BACT -------FIDGLSTKVQGRIGMSALLIETGETV-GYKADERFPMQSVYKFPIGMAALYAVD -QGILKLDKSVKVANEEYVSHSPLRDGNPDGAVTVKELLRLAVSESDGTASDVLMRLVGGA -QSVMNYLQAIGITGVIVKNTEKELGATNSVQYDNWATPIQATLLLKQFQLGKGLSVSSRA -LLMQLMTDTQTGLQRLKGNLPPGTVVAHKTGTSGTAATNDIGIITLPNGRHIAIAVFVTD -AKADQTTREGAIAQIARKVWEKy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3D3MAG5_9FLAO --kDLRNKIHEIISTKNATVGVSLKGIEDQDTL-SINGNKNTPLMSVFKFHIALAVLNHVD -KGKLKLDQKFFIKKEELLPWSPIRDEYPQGNLTLDQLLRYTVSHSDNNGCDILLNILGGT -QTVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTAILEKFYNGKVLKKETTK -YLYRIMLETSRGLTWMKAGLPEGTELAHRTGISSRAAMNDVGIVTLPNGKHYILSVYLKN -ITEEMKDTEKIIADISRVVWEYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. SN22 TaxID=2606431 RepID=A0A5A8AK04_9FLAO ----PDSKINSIIQDKKATVGISVLGFENGFKY-DKNGDQKLPMQSVFKFHIAAAVLDFVD -HGKLSMDQKVSLSASNLLPWSPLRDKYSTGSVPLSEIIEYTVAKSDNNGCDILLKLLGGT -KTVQKFMDSKGVKGFQIKYNEAEMHRDWNAQYKNYSTAVSATEVLKKLYDGKLLSKKSTE -YLMDVMLSTSTGMNKLVGQLPKGTPVARKTGASGTGAENEIAIVTLPDGKHYAIAVFVSN -STETQEVNCKMISDISKSVWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3D0WHR7_9SPHN --qDLAARISEIEKASGGRLGLGLHSPDKGLVY-AYRGDERFAMCSTFKLALAAMTLDTPG -----LREKRLHFGAGDILSYAPYAKERASSGMSGLEAAHHAVTLSDNTAANLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGALLWGDRLAPADRA -LLEEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR -AD--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas ginsengisoli TaxID=336566 RepID=UPI0009F953E6 ----LQHEAQRLVAMLPGEVGVSMLHLQSGRAV-HVNGERAFPLASVMKVPVAVHILTLVD -EGKLRLDQNVVIGPNDIYPGGPMQIH-LTPGISVRDLLHMMITVSDNNATDMLVKLGGGT -DAVTQRMRQLGINDVRIDRYIWELLAAWNRDPRDSGTTTAMAQLLASVWKGQVLSDNSTA -VLKAIMGQTRTGAGRLRGVLPPDTPVAHKTGTVGD-VINDVGVITLPDGKGEVIVAVLME -STADTAQRERVIANLARAAHDYf ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Methanosarcina mazei TaxID=2209 RepID=A0A0F8GV64_METMZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369I915_9BACT ----LRQKIQQIASKTDGTLGVGILGLENRDTL-TLNNHVHFAMQSVYKFHLGLAILNQVD -KGNLKLNQKILIQKKDLLPWSPLREKYPNGNIPLSELIQFTVAQSDNNGCDILFRIMGGP -RVVDNYIKSIGMTDVSIRTTEEEMHKTEGAQFTNWTTPWSAVQLLEKFYQKKILSPASHA -FMWKVLTEANTGSGKIKGLLPAGTLVAHKSGLSGTAATNDIGIVTLPNGKHFIISIFYGN -TKLSDKESDKVIAEVTKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI001410024F ---SLHNQIEQIAGAAQGRVGVAAMLLETGESV-ALLGDQRFPMQSVYKMPIGMAVLHLVD -QGKVTLDQKVRVETIEYVSHSPMRDQFPKGTISVAELLRYSVSESDGSASDVLMRLAGGP -KPIMAYFKSLGIKDIIIANTEKEIGGDNAVQYRNWAKPTEVVALLRLFQQGRGLSNSSRA -LLLRLMTETETGLHRLKGQLPAGTVVAHKTGTSWTAATNDVGLITLPTGQHIALAVFVSD -SKADEKTREAVIAQIALATWNFw ->[subseq from] class A beta-lactamase n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011F04D52 ---RLQNELERIAGLAKGKVGVSAVHLESGKTV-NLNPREAFPMASTVKVAIAVTLFTKIE -KGELSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGV -SAVRARLSALGIQGMSVDRTIIELLAKLQADPRDTSTPEAMVNLLSQIHSGKALNPESTA -LLLGVMERCRGGLARLKGYLPPGTVVAHKTGSLDANATDDVGIITLPDNGHIAIAVFIGK -SSQPLAEREQTIAHLTRSIYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. POL2 TaxID=2713414 RepID=UPI0013E0F516 --qDLKTSIQTILKDKKANVGVAVWHLEKQDTL-SVNGHRHLPMQSVFKLPIGLAVLDLVD -KGKFKIDQKIKFTKAEMMPHSPMRDAYPEGGLTVREMLKYVVANSDNNTCDILLDRIGGP -EVVQKYMDKIGIKDFQIVSNERIMHETPSFQYQNYWNANSANDLLNKLYTKPILKEASKK -EIIKILEETNTGLNRLKAELPVGTIVAHKTGSSATAATNDIGVITLPNKEHMIVSVFVSD -SYENDATNEKIIADIAKASFDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. AG844 TaxID=2183998 RepID=A0A2V2ZM90_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAAAVLNAID -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WZQ0_9BACT ---RLQERLNNLDSSAQGDVGIGVLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD -EGKLSLNQTVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGT -EQVTANLGRMNLRDIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLVKLQSRQLLSENSTA -LLLKIMTDSPTGQKRLKAGLPPGWSIAHKTGTGEDVATNDVGLISSPTGKHIAIAVFIAG -SKAPLEQRESVMSAVASAVVQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Agromyces sp. Root81 TaxID=1736601 RepID=A0A0Q8W255_9MICO -hrRLTEAIAELERATSVTIGVTALWHDSRRAF-RYRGDERFPMCSLFKSFAAGALVQARG -YDEEYWTTPIPFTDADVVGKETKLNRD-TWQATPEELADAAIRYSDNTAGNLLLRELGGP -QAVTTFARSLGATRTRLDRPEPQVNEATPGDERDTSTPDDIAFLLQLLLIDQGAGALTTA -RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT -DRTDAPSNHDVLADVTRLIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA8543 TaxID=2055766 RepID=A0A3C0NHT1_9CYAN -----------------------VLDLDTGERW-FRNGKQRFPMQSVFKLPVGIVVLKLVD -EGKLSLNQSVTITREQFVPWSPILKEIKGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP -EQVTAILGRMNLRDVRVDRLEQQLQPKYLTDPRDTATPEATVNLLAKLQARQLLSEDSTA -LLLKIMTDSPTGQKRLKAGLPPGWTIAHKTGTGPGAATNDVGIISSPTGKQVAISVFIAG -SKAPMEMREKLMAEIASTVVKEf ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter estronivorus TaxID=1172626 RepID=UPI0012E892AA ----FEAQIARLANGAQGRIGVAAVDLSDGHEV-AILGDQRFPMASTSKIAIAATFLDGVD -NGRWSLTSEYPLLIPVRSQFSSATAPVRKGALPAHDLIERMITRSDNNATDALLAVIGGP -EAVNRWVRKAGIKDFRIDRDIATLVRASHIDPRDSATPHAMVQLLSGLYKGRWLSQASRD -VLIGAMERCITGKRRIRALLPEDVQVAHKTGSLNN-TSSDIGIIKTSDGRAYAVAIYVTG -QG-TRLAREHRIAEIAKAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Sediminispirochaeta smaragdinae (strain DSM 11293 / JCM 15392 / SEBR 4228) TaxID=573413 RepID=E1R6Z1_SEDSS --nNLRQDIEQFLVEKKALVGVSVLGIEDNESL-SINNDKHFSMQSVYKFHIALSALHEVD -TGNLSLEDSIMLKESDLLPWSPLRETYLAGKITLAELINYTVALSDNNGSDILLRLIGGT -EKVNEYIHGLGIIDVQITTDEENMHKESDLQFENWTTPEAATELLTLFYDGKVLSKQSTD -FLWKVMAGTETGGGRIKGKLPSGTLVAHKTGTSATVAINDIGIVTLPNNNHFVMSVFVAN -SKESYETNEKIIADITKLVWNYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flagellimonas algicola TaxID=2583815 RepID=UPI00110D672C --eTLRHQIEGIISSKNATVGVAINGMDAKDTL-SINGQRHFPMQSVFKFPIALTILAEVD -KGNLSLDQKIDIKKSQLLPWSPLRKKYPEGGIPLDEIIEYTVALSDNVGCDALLRLLGEP -RAVERYFSKLGFTDFAVKINEEVMQGNWELQFLNWTTPKEANRILATFYENNLLSKKSYD -FIWDIMKGTKTGKKRLRGHLPEETIVAHKTGWSGTAAVNNIGIVFLPSGEHFTISVFVTE -SSESLETNEKIIAEISKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=UPI000E6A573B ------SELKHIEQENDVTIGVYGMNTDNGKVY-KHNPDERFAFASTYKAIASGILLNNVP ---NGKLNKKIKINEQDIVAYSPVTEKYIGKTMSLKSLVQASMLQSDNTANNKIIQEIGDI -EGFNNELKGLGDYISKPQRLEPDLNDYDPTKIADTTTPRAAATTLHKLLVSNQMDKDNQA -LLKQVMIENETGDSLIKAGVSKQYIVGDKSGQGTYGTRNDLAFIYTDHRKPIILAVYTKQ -DQKNAKPDDKIIAAAAEEAIK-- ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium angstadtii TaxID=558151 RepID=A0A0J7IFR8_9FLAO --eNLRTQLQKILSTKNATAGISVKGIEDKDTL-SINGNLNMPMMSVFKFHIALAVLNKVD -QGKWKLDQKFFVKKEELHPWSPMRDEFPDGNLTLDQLLRYTVSHSDNNGCDLLLNRLGGT -ESVQKFINKQGIRDFVIKVDEQQMSS-WENLYVNTTTPLATTELLEKFYKGKVLKKETTR -YLYQIMVETSRGITWMKAGLPKDTEVAHRTGISSRAAMNDVGIVKLPDGKHFILSVYLKN -ITEERAETEKIIADIAKAVWNYy ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=A0A5R9PYS6_9GAMM ---TLKADIELLLDSKKAKVGGSIWDHNAEPVL-SVNGDSKIPMQSVFKFHIAAAVLSEVD -KGRWSLEDKIKITPNDLDNWSPIRKKYPNGTIPLSEVIRYTVSVSDNVGCDILLSMLGGP -KKLEDYLHQSGIKDIAVKYNEENMQKVWQRQYENWTTANAANTALNQFHMSNLLSAKSHQ -FLWDVMKGSKTGRKTIKAGVPKDTQVAHKTGHSGTGAQNDIGVVFLPNGQHYYISVLVSD -SYETSETNQNIIAKISELTWQFf ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=Q5XQD3_AERCA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSLSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sp. BO-6 TaxID=2604537 RepID=UPI0013E1AFE3 ---RLAARLRILEAASGGTLGVAFLDTGSGEMI-GHNRAMRFGHASSFKLSLAALVLWRDQ -QGIEEAERQVTWAEDELMSVSPFATERLAQGATLLELAEATQKFSDNAAANILLREIGGP -ERLNEFWRAIGDSQSRLDRIEPQLNHVPAGEVRDTTTPEAMCRTVEALCFGDVLQAAQRA -LLRQWMIDTRTGLRRVRAGIPQDWRAGDKTGTSTGSLYVDIGFVAPADRAPLTFATYFRA -GAAHEPAAEAVLAQVGRVLAD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. GA093 TaxID=2683249 RepID=UPI00136555D6 --nELREQLNQIIATKHATVGISIKSIEDKDTL-SINGNLKMPMMSVFKFHIALAVLNKVD -EGKLSLTQKIFIKKEALDPWSPMAEEFPNGNLTLDQLLRYTVSHSDNNGCDILINLIGGT -KVVQKFINKQGIKDFVIKVNEEQMKS-WEKLYINTTTPLATTELLEKFYKGKVLNEATTK -YLYQIMVETSRGLTWMKAGLPENTELAHRTGLSGTNAMNDVGIVKLPNGKHFILSVYLKE -ITETKDDTEKIIADITRATWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=UPI000BE2EFEA --qRLEQELNRIAAIAKAKVGICALHLESGKQV-SLNLQERFPMASTVKIAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQNRVRTLGIQGMSVDRTIIQLIARLKTDPRDTSTPDAMVNLLTQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPLAEREQTIAHAARSIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=UPI000DBB6BB6 ---RLSDAFKLFAEQTDGTVGVAAQAIGSKEMA-TLNAGTTFPMASTFKIAVAGKIFERID -KGELTLDQMVTVDPKLLVGGMAIQTPHPGIALSVYNLLEFMITQSDNTSTDVLVQLAGGP -AGVTAWLRGQGISGQRVDGDTAHLIYPFNADPRDASTPEAMVQLLLRIHSGKAMSAKSTK -TLIEIMERCRTGEKRLKGLLPSDTVIAHKTGTLNS-VANDVGIITLPNGKQFAIAVFVKG -DTKGKDVQDKVIADIARVAYDHf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter luteus TaxID=1581420 RepID=A0A0G9MUW2_9SPHN ----LAQRIAQIAEGSRGRIGVAAIDLSNGQSI-SVLGDQRFPMASTSKIAIAATFLEMVD -QGRASLSSEYPMLYPVSSRSSSVAPVRRGEYMSAQNLIEIMITRSSNQATDALLEAVGGP -SAVNAWARRAGLTEFSLDRDIATLVRAHHIDMRDSATPQTMVQLLSGIYQGRWLSPESRR -VILGAMERCRTGTRRIPAMLPSGVSVAHKTGSLNN-TSSDIGILTAPDGRTIAVAIYVTG -QG-SRPNREARIASIARAIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Croceicoccus mobilis TaxID=1703339 RepID=UPI0009ED5BA8 ---QALAALRALDTQAGGTLGAFILDIANGENI-VWQSSRRFCHCSSFKLSLAALMWREVD -AGRLDPEEMLPYTRDDLMAVSPVTTRNLDESLPIRTLARAIQVTSDNAAANLLLRRLGGP -KGLTAFWRSIGDDVSRLDAYEPELNRIPPGTTENSTTPEAMARTVARLTTGDVLESDSRE -TLRQWMADTVTGTRRLRAGVPDEWWVGDKTGTSLPSTYVDIGLMIPAGGTPLAVAAYYVT -PEEMNPESEAVLAQVGRIAAD-- ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TDU6_9BACT --dALRSNIQQIVSSKNAIVGVSIIGNNGKDTM-SLHGDRRFPMQSVFKFHIALAVLSEID -KGKLSLDQKIKIGKDELLPWSPLRDENPNGGFTIERLIQYSVSNSDNTACDVLIRLIGTP -KTVEEYFKKNNIQDIQITYNEEEMQSKWENMFENWTTPKAASETLKMFYENNLLSKSSYD -FFWKTNIETTTGEKRIRGLLPKGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE -SKENFDTNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase n=1 Tax=Allofrancisella guangzhouensis TaxID=594679 RepID=A0A0A8E6P4_9GAMM ---ETSEQIKKLEIKYGGKIGIYLIDYNNKSHF-GYNQNFYFPICSVYKFLVVGAILKESM -ITPNFLNEKIKINKNDIIGYTPITSENIDKKLTIEELSKAAI-LSDNTAANLLIKKLGGL -KNLNKFIWSLDDKDTKITVNEPTINNVDLRDSLNKTTPQIIAKDLNKIAFKKVLNKKYQL -IFKKWLQENDTGKNRIAFSIPKEWKVGDKTGTCEYGTTNDVAIIWPKNKKPIIISVLYTQ -VNKNAKANDIVIQKITKILLD-- ->[subseq from] PER family class A extended-spectrum beta-lactamase n=1 Tax=Rheinheimera sp. KL1 TaxID=1635005 RepID=UPI0006A95051 ----LKEQIESIVIEKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELIGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSASSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGYSGTAATNDIGIILLPDGRSLLVAVFVKD -SAESTRTNEAIIAQVAQAAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. JCM 19047 TaxID=1460641 RepID=W7ZPJ7_9BACI -----AATFSVLEDHYDARLGVYALDTGNGQTI-AYNEDERFAYASTHKALAVGVLLQQLS ---LDELDTQILFSEADLVTYSPITEQHVETGMSLHEISDARFATATIQRLILFSMKLAVH -QGLKRHSEKLEDEVTEPERIETELNDVKPGETRDTSTAKALAESLYAFSLGDALDEEKQT -LLNDWLIHNTTGDALIRSGVPEGWLVGDKTGSASYGTRNDIGIIWPPDEDPIVIAVLSSK -EQADAESDDALIAEATEAAL--- ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcaceae TaxID=90964 RepID=Q49V79_STAS1 ---TFAKDIEQIENEYNTKVGIYGINTENGKAY-QHNADERFTFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000AC01B91 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLSSILTSNEMNESNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. OV705 TaxID=1500289 RepID=UPI000648FA97 --eRLRKEIQQIIASKNATVGISIKNIEDKDTL-SINGNSMMPMMSVFKFHIALAVLDQVD -KGKLKLNQKFFIKKEDLLPWSPIQEEFPNGNLTLDQLLKYTVSHSDNNGCDILLRILGGT -EPVQKFINQQGIKDFIIQVNEQQMS-NWDNLYLNVTTPIATTALLEKFYNGKVLKENTSQ -YLYQIMTETSRGLTWMKAGLPDHTELAHRTGISSRAAMNDVGIFKLPNGKHIILSVYLKN -ITEERTDTEKLIADIARATYNYy ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8YX01_9BACT ---DLQKQIATIAKSIPGRVGVAASVVETGEVV-QWQGNAEFPMQSVYKLPIAMAVLNQVD -EGRLKFDQRVNVEKVNYIAHSPIRDEYQDGTISISELLRYAVSESDGSASDIVMAQAGGP -AVVMSYLNSIGVRDIKVADTERTLGLDATSQYRNWAKPVEAVKLLGLLQQGVGLSASSRS -YLLRLMTETETGLNRLKGQLPQGVKVAHKTGTSQTAATNDIGLITVDEHKHIALAVFIKD -SAASTKEREAVIAQVAKLVYDRw ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. 17S1E7 TaxID=2497456 RepID=UPI000F86BECC ----LEPKINSILKNKKATVAVSVLGFENGFRY-DKNGDKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKEIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QPVQKFMDTKGIKDFQIKYNEEDMHKDWNVQYQNYSTTRSAANALKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIVTLPNGRHYALAVFVSN -STETDAVNCKMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) TaxID=504472 RepID=D2QNF5_SPILD --qRLEQELNRIAAIAKAKVGICALHLESGKQV-SLNLQERFPMASTVKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLEVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQNRLKTLGIQGMSVDRTIIQLIARLKTDPRDTSTPDAMVNLLAQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPLAEREQTIAHAARSIYDFf ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium lathyri TaxID=395933 RepID=A0A511Y8N8_9FLAO ----LEQKINSIIKDKKATVGVSVLGFENNFKY-SKNEDMPFPTLSVFKFHIACAVLDLVD -KGKLSLGQKIFISKSDLMEWSPFREKHPDGNVSLNEIIDYTVALSDNNLCDVLLKLIGGT -KTVQGFMDSKGVKGFQIKYNENEMHKDWKALYENYSTTNSAVQLLKKFHDGKLLSKKSTD -YLMQIMIGTKTGTNKIVEQLPKNTPVAHKTGASGKNAENDMGIITLPNGKHYAIAIFVSN -SMESNAVNCRLVSDISKAVWDDf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium limigenitum TaxID=1612149 RepID=A0A1K2ITQ5_9FLAO ----LEKKINSIIKDKKATVAVSVLGFENGFKY-NKNGEKKLPMQSVFKFHIAAAVLDLVD -KGKLSLDKKILLDKSNLLEWSPLRDKYKDKNVPLSEIIDQTVAMSDNNGCDILLKLIGGT -QTVQKFMDSKGVKGFQIKFNEEEMHKDWQAQYENYSTTNSAVQVLKKFYDGKLLSKKSTD -YLMKVMLGTKTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIVTLPNGKHYAIALFVSN -STETDAVNCKIISDISKSVWDHf ->[subseq from] Beta-lactamase n=1 Tax=Thioclava arenosa TaxID=1795308 RepID=A0A2A4CN74_9RHOB ---SVGAAIERVATKLAGRIGFAAQEIGGDDVI-AFNGDEAFVMASTYKVAIAAAVLDRVD -KGELSLDQMVEVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP -AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD -FLIDVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] Beta-lactamase n=1 Tax=bacterium BRH_c32 TaxID=1734400 RepID=A0A101VYC7_9BACT ---SLRERITQIIEGKDAIVGIAVEGYDGKDTL-SINGSKRFPMQSVFKFHIALAVLNEVD -KGELNLNQKITITKEDLIPYSPIRDKYPNGTMKLSEILTYTVGESDNVGCDILLKLIGGP -QVVEKYLHSKNIDDVAIIYNEKDQQSNWENQFQNWTTPHSANQTLIKYYENNLLSKRSYD -FLWKTMEGSKTGKKSIRGELPKNSVVAHKTGHSGTAAVNDIRIVFLPNGKYFYLTVFVSN -SKEDEEINQKIIAEVSRASWDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. JV274 TaxID=1932669 RepID=UPI00098492EF ----LEQKIHSILKNKKATVGVAVLGFENGFTY-DKNADKNLPMQSVFKFHIAAAVLNAVD -QRKLSLDQKIVLNKSNLLEWSPLRDKYPGGNVPLSEVIEYTVAKSDNNGCDILLKLLGGT -QPVQKFMDSKGVKGFQIKYNEEGMHKDWKAQYENYSTTKSAVHVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGTHYALAVFVSN -SMETDAVNCRMISDISKEVWEYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=Q5MDG3_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGDW------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GX03_9BACT --qRLEQELNRIAAIAKAKVGICALHLESGKQV-SLNLQERFPMASTVKIAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQNRVRTLGIQGMSVDRTIIQLIARLKTDPRDTSTPDAMVNLLTQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTIIAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGD -SPMPLAEREQTIAHAARSIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium tardaugens NBRC 16725 TaxID=1219035 RepID=U2ZQ63_9SPHN ----LEAQVARYADGSKGRIGVAAVDLSSGREI-AILGDQRFPMASTSKVAIAATFLDGVD -KGKWSLSSEFPLLVAVASPSSAIAPVRKSTYMSASQLIDLMITRSSNPATDALLAAIGGP -AAVNRWMRNAGINDFRIDRDIATLVRASHIDQRDSATPRAMVQLLSGLHQGRWLSASSRR -VIMSAMERCVTGKRRIPALLPVGVQVAHKTGSLNN-TSSDIGIISGPDGRTYAVAIYVTG -QG-TRLAREERIAQIARAIYDGy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 7 TaxID=2035214 RepID=A0A497UQ61_9FLAO --sQLEQKVSSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNSVD -KGRLSLDQKIKLNKSNLLEWSPLRDQYAGKDIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYQNYSTTNSAVDVLKKFYDGKLLSKKSTD -YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN -SMETDAVNCKMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii Naval-57 TaxID=903927 RepID=A0A656I7Y0_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSDSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X9B1_9BACT ---------QEIASVTKGPVGAAAMIVETGEKA-SISGSEHFPMQSVYKLPIAMAVLKRID -NNTLTFDDKIAVKPKDFVSEFSIAIKYPKGALSIRELLDYMISESDGTACDALMRMLGGP -EAVTKNLREWGVNDIVLATYEQDMFKTPAVSFQNWSTPDAMVQLLRLLQTEKVLSAERRD -ILLSLMIKSRPGQQRIKGLLPPGTTVAHKTGTSGTTATNDVGIVTLPNGRHLAIAVFVSS -TTADQETREGVIAKIARAASDCw ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Syntrophaceae bacterium PtaB.Bin095 TaxID=1811717 RepID=A0A1V4XDD3_9DELT ---RLISEIGRLARLSGGVVGVSAVHIESQKRI-SFNGRERFPMASTYKIPIAVQLITLVE -RGELAWDRMVEIRETDLRPGSGVLAKLFDKPVSLRNLFEIMMVVSDNTATDLLLSIAGGP -GAVTRQMRAVGIVDIDVSRSVFEMIAEFEADGRDTATPDAVVSLLQGIYRGDFLRPESAG -MLLDAMRRSQTGEARLKGMLPPGTPVAHKSGTLG-GSTNDAGIISLPDGGHVAIAIFVKT -SRKEATEREKAIAEIARAVYDFy ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Citrobacter freundii complex TaxID=1344959 RepID=A0A3Q8H2Z2_9ENTR ------------------------------------------------------------- ------LQQQVVIKPSDLVNYNPIAEKHVNSTMTLAELSAAALQYSDNTAMNKLIAHVGGP -QKVTAFAREVGDSTFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGETQRA -QLVTWLKGNTTGNASIKAGLPATWVVGDKTGSGDYGTTNDIAVIWPENHAPLIL------ ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=B2CD46_ECOLX --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDH---------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T3L9_9BACT --dKLKTEIDSLVKSKNATVGVSIIANNFKDTI-NINENLHYPMQSVFKFPIALAVLSEVD -KGNLKLNQEIIIFPKDLLPWSPIREKFPDGTMTVADIIKYTMAQSDNNGCDILLRLLGGT -TAVEEFLSQHQITDISIKFNEEDMHKEWNIQFQNWATPIALTKLLAKFYVDNILSKESYE -FLWRVMSETTTGTDRLKGQLPQDIIIAHKTGTSGTAAINDIGIIILPNGNPIFISVLVSN -STEDHGANEKIISDIAKKVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000C7ACC3A ------------------------------------------------------------- -----------------LVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLASQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf394 TaxID=1736361 RepID=A0A0T0M9C1_9FLAO ----LDKKINSIIKGKKATVGISVLGFENGFKY-SKNAEKKLPMQSVFKFHIAAAILDYVD -KGKLSLDQKVLLTKDNLMQWSPLRDKYPNGGVPLSEILELTVAQSDNSGCDILLGLLGGP -KTVQQFFDAKNVKNFQIISGEAEMHKDWNVQYKNYSTANAATDALKKFYDGKLLSEKSTD -YLMKVMLSTSTGKNKLIEQLPKNTPVARKTGASGTGAENEIAVVTLPNGRHYAIAVFVSN -STESSDVNCKMISDISKVVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DCB0D5 --qRLEHELERIAKLAKGNVGVCALHLESGKQV-SMNLQERFPMASTVKVAIAVQLFTLIE -KGDLSMMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGP -TAVQNRLKTLGITGMSVDRTIIQLLAKLKTDPRDTSTPAAMVNLLTQIYRGRALKPENRA -LLLGVMERCRGGAARLKGYLPPNTIVAHKTGSLGGSATDDIGIITLPGDGHIAIAVFVGD -SPMPLTEREQVIAHTARSIYDYf ->[subseq from] class A beta-lactamase n=2 Tax=Citromicrobium TaxID=72173 RepID=UPI0009E7D91A --eQLAAQIDRLEAASGGRLGLALFSQDEGLVF-AHRGAERFAMCSTFKLALAAMALETPG -----VREERLDFGADDILSYAPYAKGRAQIGMSGLEAAHHAVTLSDNTAANLLLVRLGGP -EAFTAWLRDAGDRVTRLDRNEPTLNENAPGDPRDTTTPGAKAELVGNLLWGDRLSATDRG -ILHGWLVETSTGMARLRGGLPDGWNAGDKTGTCGQPEFNDIAVFETPSGSRYVLAAFLDR -PKGTSAEADAVLADAARVVAE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Plantibacter sp. YR521 TaxID=2135468 RepID=A0A495AY68_9MICO ---EIAAKIGRIEGEFAVTVGAVAIG-ESGQVV-EYNGEARMPYASTMKVFVAAALLASTP -VDERETIVRWTQAQLDVAGYSPLTSEHLDDGLTLDALAEAAVRDSDNTAANLVMESLDGP -SGVQDFLRALGDPTTVVTEYEPELNAVVPGSDQNTSTPLALATDLKTIFEGDALEQGSRE -TLLDWMTGNATGDALIRAAAPSGWTVADKSGGAG-GVRNDVAVVTTESGEQIYIAILTAT -KDPAAAYTDEVVERVARDLLAEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD68_KLEOX --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDH---------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingosinicella microcystinivorans TaxID=335406 RepID=A0A495RKN2_SPHMI ---RLSDAFKLFAEQTDGTVGVAAQAIGSKEMA-TLNAGTTFPMASTFKIAVAGKIFERID -KGELTLDQMVTVDPKLLVGGMAIQTPHPGIALSVYNLLEFMITQSDNTSTDVLVQLAGGP -AGVTAWLRGQGISGQRVDGDTAHLIYPFNADPRDASTPEAMVQLLLRIHSGKAMSAKSTK -TLIEIMERCRTGEKRLKGLLPSDTVIAHKTGTLNS-VANDVGIITLPNGKQFAIAVFVKG -DTKGKDVQDKVIADIARVAYDHf ->[subseq from] Beta-lactamase n=1 Tax=Aquimarina sp. MAR_2010_214 TaxID=1250026 RepID=A0A2N3T2Y7_9FLAO ----LRKKIEQIVSEKNAVVGVSIIGNNGKDTL-SLYGDKRFPMQSVFKFHIALAVLSEVD -KGILSLDQIIEIDKDELLPWSPLRDENPNGGFTIKKLIQYTVSHSDNTACDVLIRLIGTP -KTVEEYIKKSGIEDIQITFNEEEMQAKWENMFQNWTTPNAASETLKIFFENNLLSKSSYD -FFWKTNKETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKYFIISVFVTD -SQENFKTNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter sp. SA-A5-114 TaxID=502288 RepID=B2CD65_9ENTR --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDH---------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013307FC4 ------------------------------------------PMMSTFKVLLCGAILVRVD -KGLEQLERRITYNKHDLDDYSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP -AGLTHFLRSTGDSYTRLDRHEPSLNGAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK -KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSR---------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Aeromonas sp. GK7 TaxID=1009023 RepID=K4EJN1_9GAMM ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSLSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQAAQTAYQ-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella limosa TaxID=370978 RepID=UPI00041BCABA ---DLKKKISQIVAGKKAKVGVAILGPTPTDTL-SFYGNERFPMQSVFKLHIGLAMLSEVD -KGKFKLNQPINVGKEDLIPYSPLRDAHPNGGIELSKIIEYTVAESDNVGCELLLKLLGGP -KFVEQYLLQRGFKNVSIKINEQVMQKNWELQYQNWTTPKAANELLTAYYFKKLLSAKSHE -FLWKVMKGTKTGKNRLRAQLPPETVLAHKTGSSGTAAVNDIGVLILPSGSPVFISIFVTN -STENEATNEKIIADIGKATWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium takakiae TaxID=1302685 RepID=A0A1M4W5Q9_9FLAO --sALEQKINSIIKDKNATVGISVLGFENGFKY-NKNADKKLPMQSVFKFHIAAAVLDYVD -KGKLSLDQKILLDKTNLHEWSPLRDKYPQGNVPLSEILEYTVAKSDNNGCDILLTLIGGT -QTVQKFMNSKGVKGFQIKFNEEEMHKDWNAQYENYSTAVSATDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPENTPAARKTGASGTGAENEIAIITLPNGKHYALAVFVSN -STETDVVNCKMISDISKSVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium chaponense TaxID=713588 RepID=A0A1N7M618_9FLAO --qDLKKEINAITNDKNATVAVSVTGIDFPLHFeNKNGEKKLPMLSVFKFHIALAVLNKVD -QGKLKLDQPIFIKKADLLEWSPIREKYPDGNMPLSELIKYTVAKSDNNGCDLLLRLIGGT -ETVQKFINNKGIKNFTIKADEAQMHKGYEFMYWNTTSTNDSNLLLMNFFDGKVLSKNSTS -FLMKTMIETTTGTTKIVAQLPKGTPVAHKTGSSGKDAENDIGIITLPNGKHYAISVFVSD -SMETEETNTKIIADISKRVFDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Hymenobacter terrenus TaxID=1629124 RepID=UPI000619AACA --eSLEQRINRLLVAKKATIGISIYCFETKEAV-SINGNEHFPMLSVFKLHIAMAVLNEID -KGRFSLNQRIHVKPEDLLPFSPLRDEYPNGNIPLAKIIEYTVGKSDNSGCEILLELIGGT -QMVNKYFRKAGMKDICIQVNEEEMHKNWNDQFLNWTTPVSAVEVLKLIYSRKLLSKTSSD -FLWNSMAATSTAGKRIKGNIPVDAVVAHKTGTGRTAAVNDIGIVASPNGRHFAVSVFVAN -SLENIETNEKVIADITRLAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140CWH6_ECOLX ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHYPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWDYy ->[subseq from] Beta-lactamase n=1 Tax=Stenotrophomonas sp. HMWF022 TaxID=2056858 RepID=A0A2R7PPR9_9GAMM -----ASDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDRRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRATGDTITRSDRLEPELNSFALDDPRDTTTPAAIAATLRRLVLGDALKPA--- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Roseateles depolymerans TaxID=76731 RepID=A0A2W5DWC3_9BURK ---DLPAALQALESRAGGRLGFAVLDTGSGRLQ-GLRLDERFGMCSTFKLPLAALTLRAVE -QGELQ-DDWVALGEITPRDFAPATRAQLPAGMKLLALAEAAQTTSDNIAANLLLQRLGGP -AGFTQRLRALGDTVTRLDRIEPSMNLVLPGDERDTTSPAAMAHTVAAILTGSWLRPEGVA -TLRRWTEATRTGARRLRAGLPADWPAGDKTGTGLPDRTNDVAIVWPAGRAPWVMAAYYEG -RGQMPAADEAVLAEAARLAV--- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium oncorhynchi TaxID=741074 RepID=A0A316X0U9_9FLAO --qDLRNKINTITSTKNATVGISVKGIEDKDTL-SINGNKETPLMSVFKFHIALAVLNRVD -KGKLKLNQKFFIKKEDLIPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -DSVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTALLEKFYNGKVLRKETTK -YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISSRAAMNDVGIVKLPNGKHFILSIYLKN -INEEMAVTEKIIADISNAVWEYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Providencia rettgeri TaxID=587 RepID=C0KTK2_PRORE ----LKGQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI0010117D0F ---TFAKDINQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Syntrophus sp. PtaB.Bin138 TaxID=1811711 RepID=A0A1V4XP62_9DELT ---RLEQEVKRLAALAGGTVGVSALHIESGRSF-SFNGGERFPMASVYKIPIAVQLLRRVD -RGEVRLNSTVTLRSGDIHPGSGRLIKTFKKKYSVRELLELMLLISDNTASDAILKLAGGP -AAVTAAMKSLGIQEMDVSRPTLNMLARFHTDRRDTASPDAMTSLLAMVYDGTALQPETTS -VLLGIMERCQTGNSRIKDLIPPGMKVANKTGTIGPSMVNDAAILTLPGEGHVALAIFIKT -SNRSITQQEQAMAQIARYLYDYy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Syntrophus sp. PtaU1.Bin005 TaxID=1811712 RepID=A0A1V5DL53_9DELT ---RLEQEVKRLAALAGGTVGVSALHIESGRSF-SFNGGERFPMASVYKIPIAVQLLRRVD -RGEVRLNSTVTLRSGDIHPGSGRLIKTFKKKYSVRELLELMLLISDNTASDAILKLAGGP -AAVTAAMKSLGIQEMDVSRPTLNMLARFHTDRRDTASPDAMTSLLAMVYDGTALQPETTS -VLLGIMERCQTGNSRIKDLIPPGMKVANKTGTIGPSMVNDAAILTLPGEGHVALAIFIKT -SNRSITQQEQAMAQIARYLYDYy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium circumlabens TaxID=2133765 RepID=A0A4Y7U8M7_9FLAO --nELRQQLQQLIAGKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALAVLNKVD -EGKLSLTQEIFIKKKDLHEWSPMREEYPNGDLTLDKLLRYTISHSDNNGCDILIDLVGGT -KEVQRFINKQGIKDFVIKVNEEQMKT-WKNLYINTTTPLATTELLEKFFKGEILKENTTK -YLYQIMTETSRGITWMKAGLPENTELAHRTGMSGTNAMNDIGIVKLPNGKHFILAVYLKN -ITETQEDTEKIIADITRATWGYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter suwonensis TaxID=332999 RepID=UPI0011A838D4 ----LNDKIQQIIASKHAKVGIAIKGPNERDAL-SINGNEHFPLQSVFKFHIALAVLSQVD -KGKFSLGQKIKISKKDLLPYSPIRDRYPDGVLPLSEILAYTVSQSDNVGCDILMRMIGGP -EFVEKYCNSIGIHDVSIKINEEEQQGNWNSQFKNWTTPKAANNILELFYMNNLLSKKSHH -FIWKVMRKTKTGAHRLRGLLPKNTLIAHKTGSSGTAAVNDIGIVFLPNGSYYFISVFVTE -STENEVTNEKIIADINKEAWEYf ->[subseq from] Beta-lactamase n=1 Tax=Tenacibaculum sp. SG-28 TaxID=754426 RepID=A0A2S7TLW9_9FLAO ----IRSKIDSLLALKKATVGIAISGVGKGDTL-SYNGHKHFPMQSVFKFPVALAVLHEVQ -CGRLSLAQKVHINKDDLLPWSPLQKKYPKGVLSLAEILQYTVAWSDNVGCDVLLKLLGGP -LTVEKYFHRLGFTDIAVKINEETMQSNWDLQFLNWTTPKEANTILKQFFTNGLLSAPNYT -FIWDLMKATKTGKNRLKGKLPTGTIVAHKTGSSGKHAVNDIGIVFLPNGNYYLLSVFVAN -SKESFKTNEKIIADISKVVWNYf ->[subseq from] Putative beta-lactamase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4J5Y6_9CYAN -----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSGIAVLKQVD -EGKISLKQLVTIMRQDFAPSSPMIKEFKGDRIPLRNVLESSVGISDNTAADALVRLLGGT -KQVNAILSKLQIRNIRVDRLEQQMQPKYLTDPRDTATPEAMVDLLAKLNSNQLLSENSTA -LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGAGTATNDVGIVSSPDGKRVAIAVFIAG -SKAPLEEREKVMSNIASRVVQ-- ->[subseq from] Serine hydrolase n=1 Tax=Larkinella knui TaxID=2025310 RepID=A0A3P1CNP2_9BACT --qRLNQELERIVKLAKGKVGICALHLESGQQI-SLNLKERFPMASTIKVAIAVELLTKIE -KGELSLMTIVDLQPSDLHPGSGTLDVLFNKPLSVQNLLELMMVISDNSATDILLRLVGGV -EPVRERLKILGIQGMSIDRSIIQLLAKLETDPRDTSTPEAMVNLLTQIYRGKALKPASRD -LLLAVMERCRGGLNRLKGYLPPATVVAHKTGSLDGSATDDVGIITLPGDGHIAIAVFVGE -SPQPLEQREQTIAHVTRTIYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. Aq349 TaxID=1192023 RepID=UPI000D55CCF1 ----LRKKIEQIVSDKNAVVGVSIIGNDGKDTL-SLDGDKRFPMQSVFKFHIALAVLSEVD -KGTLSLDQIVEIDKDELLPWSPLRDENPNGGFTIERLIQYTVSHSDNTACDILIRLIGTP -KTVEQYIKKSGIEDIQITFNEEGLQAKWENMFQNWTTPNAASETLKIFFENNLLSKSSYD -FFWKTNKETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKYFIISVFVTD -SQENFKTNQKIIADIAKATYDFy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL47_ECOLX ------------------------------------------------KVMAAAAVLKKSE -XEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium oncorhynchi TaxID=741074 RepID=A0A316X579_9FLAO --sELEQKISSIIKGKKATVGVSVLGFESNFKY-NKNGDQKLPLMSVFKFHIACAALDLVD -KGKLSLEQKIFIKKADLHEWSPFREKYPNGNITLHEIIDYTVALSDNNLCDVLIKLVGGT -KAVQQFMDSKGVKNFQIKYTEHDMANDWKALYENYSTTNSAVQMLKTFYDGKLLSKKSTN -YLMQIMLGTKTGTNKIIEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVVN -STEAEAINCRIVSDISRAVWDNf ->[subseq from] Beta-lactamase class A n=1 Tax=Soonwooa buanensis TaxID=619805 RepID=A0A1T5GB87_9FLAO --kDLRTSIQEIVKNKKANIGVAVWHLEKQDTL-SVNGHRHVPMQSVFKLPIGLAILDLVD -KGKFKIDQKIKFTKEELLPHSPLRDANPNGGLTLLEMIKYTVANSDNNGCDILLDRIGGV -DVVQKYMNRIGIKDFQIATNEQEMHVVTELQYQNYWNANSANDLLEKLYTKPILKEASKK -EMIKILEETNTGVKRLKGELPQGTLVAHKTGTSYTAATNDVGVITLPNKEHVIVSVFVSD -SYEKEATNEKIIADIAKASFDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1YZQ0_ECOLX ------------------------------------------------------------- -------NQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVLGDKTGSGGYGTTNDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. ACN2 TaxID=1975676 RepID=UPI000BB3DE13 --nELRNQLQQIISSKNATVGVSIKNIEDKDTL-SINGNLKMPMMSVFKFHIALAVLHKVD -EGEFNLTQEIFVKKKDLKEWSPMKEDYPEGNLTLDKILRYTVSHSDNNGCDILIKLVGGT -KYIQKFINEQGIKDFVIKVNEDQMKT-WKNLYINTTTPLATTELLEKFFKGKVLKEETTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHLIVSVYLKD -ITEKKEDTEKIVADITKAVWNYf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ABE17A ---QFRTKIEQIAQDAQGRVGVAATLLETGESV-GFHENEQYPMQSVYKLPIGMAVLHQVD -QGKLVLAQLVHVSKSDYISHSPIRDKFPQGAITLAELLRYAVSESDGSASDVLLRVLGGA -EVVMNYLRTLGITGVMVLNTEREIGSDNAVQYRNWAKPSQLVALLKAVQAGKGLSRTSHA -LLLHLLTDTQTGRQRLKGLLPAGSLVAHKTGTSWTAATNDVGNLTLPDGRHIAIAVLVSD -AKADATTREAVIARIAKAAWDYw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0H3WJJ7_KLEPN --------------------------------------EETFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLR------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WR07_9BACT ---------QEIASVTKGPVGAAAMIVETGEPV-SINGGDHFPMQSVYKLPIAMAVLSRID -NKTLTFDQKVRVDPKDFVSEFSIATKYPNGAISIRELLDYMISESDGTACDALMRMLGGP -EVVTKYLRDLGVQDVVLATYEQDMFKTPSVSFQNWSTPEAMIQILKLLQVGKVLSEERRD -ILLSLMIKSRPGPQRIKGLLPAGTTVAHKTGTSATTATNDVGLITLPSGQHLAIAVFVSN -TTADQKTREAVIAKIARAATDCw ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A411DMH2_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFRY-NKNADKKLPMQSVFKFHIATAVLNAVD -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7H7_9BACT ----LHKRIKELAATVDGQAGVAIMDLSSKDTL-LYNVHGRFAMQSVYKFQLGLAVLNEID -KEALSLDKKIRLTKENLLPYSPMRDKYPGGNLPLRDVLKYLVTNSDNNACDILFKELGGT -KRVNRYVHDLGVNEMEIAATEDEMHQGYDVQFTNWSTPRATLQLLEMFYDKKLLKPASQE -LMWKMMVETTTGPKRLKGLLPEGVEAAHRTGLGDRDAVNDVGIVKLPNGKYYAIVVYIGR -AKGELPDLEKVIAEISLAAYK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter auburnensis TaxID=1457233 RepID=A0A2H9VNJ6_9SPHI ---NIQQQITDIARDAKGIVSFTALNLETRDSV-SYHGEGQMVMQSVMKFPIALAVLHEVE -RGKFSLDQTFKISDRDMHHNGPLFEKYPKGVIPLSELLTYMVSYSDNNACDILLDKIGGV -KPVMDNLRRLRVKGIVVDASELDMSAAWEVQYTNWCKPAAMVQLLDVFYQGKALDKANTD -TLIKKMLQTTTGPKQIKGLLPQGTVVAHKTGRSNTAATNDVGIITLPNGQHLAIAIFIGN -STADLDTRESVIARITKALWD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD71_ECOLX --------------------------------------KERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQD----------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI001178C2C2 ------------------------------------------------------------- -------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQXI -QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFXK -NKKGAVSPDSIIERIXRILM--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD64_ECOLX --------------------------------------EERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQTT---------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000F44FBF3 --kDLKNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNRVD -EGILKLDQKFFIKKEDLLPWSPIREEYPQGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -ETVQKFINQQGIKDFTIKVNEKEMSS-FEKCYLNTTTPLATTELLEKFYKGKVLKKETTK -YLYQVMVETSRGLNWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSIYLKN -IKEEMADTEKIISDISHAVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium detergens TaxID=1145106 RepID=A0A420B7R0_9SPHI ----LRNKIAQIVSDKDAIVGVSIIGNNGQDTI-SLNGDRRFPMQSVFKFHIALAVLSEID -KGNLSLDKKIEIGKDELLPWSPLRDENPNGGFTIEKLIQYTVSHSDNTACDVLIRLIGTP -KTVEDYFKKNNIKEIQITYNEEEMQAKWENMFQNWTTPKAASETIKMFYENNLLSKSSYD -FFWKTNIETTTGANRIKGQLPKETIVAHKTGWSGTAAVNNIGLVFLPNGEHFIISVFVSE -SKENFDANEKIIADIAKATYDFy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CF356 TaxID=1500283 RepID=UPI000647B5E4 ----LDQKISSIIKDKKATVGVSVLGFEDGFKY-DKNGNKNLPTLSVFKFHIACAVLNLVD -QGKLSLDQKVVLKESELLPWSPIKEKYPTGDLTLDEIIDYTVALSDNNGCDKLLKMIGGT -QTVQKFMDSKGVKGFQIKVNEDEMHKSWKTQYENYSTTNSAVNLLKSFHNRKILSKKSTD -YLMKIMIGTKTGMNKLVEQLPKNTPVAHKTGASGTVAENDMGIVTLPNGKHYAIAVFVNN -STETDLVNCKMISDISKIVWDYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WYE2_9BACT ---RLQERLDNLDSSAQGDVGIGVLDLDTGESW-FRNGKQWFPMQSVFKLPVGIVVLKLVD -EGKLSLNQTVTITREQFVPWSPILKEITGDRFTVQYLLQRAVGDSDNTAADALVRLVGGP -EQVTDILGRMNLRDIRVDRLEQQLQPRYLTDPRDTATPEGMIDLLVKLQSRQLLSEDSTA -LLLKIMTDSPTGQQRLKAGLPPGWSIAHKTGTGENVATNDVGLISSPTGRRVAIAVFIAG -SKAPLEQRESVMSAVASAVVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Enterococcus faecalis TaxID=1351 RepID=UPI00132F8204 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHATRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLA--- ------------------------------------------------------------- ------------------------ ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bacteroidetes bacterium ADurb.Bin397 TaxID=1852812 RepID=A0A1V5P1K5_9BACT ----WKQEIRNIATKYKAVTGVSIYGNSGRDTL-TVNGSAHLPMQSVYKFHIALAVLSEVD -KGKLDLNQKIKITTKDLWPWSPIRDKYPEGTLTLAQILQYTVSESDNNGCDLLLRLLGGP -SFVDNYFRMANFSDISIKATEQEMHSGWDVQFSNWTTPIAATNLLKAFYTNELLSKNSYN -FLLATMKATSTGKQRIKGLLPSGTVVAHKTGTGGTSAVNDIGIVFLPKGNYFLISVMVTE -SGESFETNEKIIADISRIAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus saprophyticus subsp. saprophyticus TaxID=147452 RepID=A0A380HNL2_STASA ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNNYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WX97_9BACT --qRLERELQRISTLAKGKVGICALHLESGKQV-SLNIQERFPMASTVKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQKRVNALGIQGMSVDRTIIQLLAKLATDPRDTSTPEAMVNLLAQIYRGTALKPDSRA -LLLGVMERCRGGVARLKGYLPPNTVIAHKTGSLNNLATDDVGIITLPDEGHIAIAVFVGD -SPMPLAEREQVIAQSARAIYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. NYYP31 TaxID=2546448 RepID=UPI0012E2DFF7 ----LRNKIEQIVSDKNAIVGVSIIGNNGNDTL-SLHGDRRFPMQSVFKFHIALAVLSEID -KGNLSLDQKIKIDKDELLPWSPLRDENPNGGFTIEKLIQYSVSHSDNTACDVLIRLIGTP -KTVEGYIKKSGILDIQITFNEEDMQAKWENMFQNWTTPKAASETLELFYGSNLLSKNSYD -FFWKTNKETTTGNNRIKGQLPAETIVAHKTGWSGTAAVNNIGIVFLPNGQHFIISVFVSE -SKENFDTNEKIIADIAKVTYDFf ->[subseq from] Beta-lactamase n=1 Tax=Lutimaribacter saemankumensis TaxID=490829 RepID=A0A1G8TJT7_9RHOB ---SVGAAIERVATKLAGRIGFAAQEIGDDEVI-AFNGDETFVMASTYKVAIAAAVLDRVD -KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP -AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD -FLIDVMSRTRTGAGRLKGLMPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E8FF61_9PLAN --sKLERRLKPLIQRHKGQVGAAIKNLRTGESF-TWRADEPMPTASLIKLAVMVEVYRQVE -KKRIDLDDRLRLDEKDKVPGSGVLRLYFSKGLPLRDAVRLMMAVSDNTATNLVLDHI-GL -KATNTTMQRLGHPHTRIHAKVFRRETSIDPERSGSTSATEMVALLEALHSGDLVSAEACV -EMLAHLGACES-TDRIPRYLPTGTKVAHKTGSVAR-VRTDAGIIDSPAG-PIAICVLTAE -NEGPENAAGRLIANVARAAWLHf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00114D2817 ---TFAKDIEQIENEYNTKVGIYGINTENGKAY-QHNADERFTFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTADNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. IITKGP-BTPF85 TaxID=1338009 RepID=A0A0M3CHP4_9SPHI ----LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID -KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP -QVVESYFAKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD -FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPNGEYFVISVFVTH -SKENQETNERIISDIAKAAWDFf ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium sp. JUb20 TaxID=2485110 RepID=A0A4V2TPY3_9SPHI ----LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID -KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP -QVVESYFAKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD -FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPNGEYFVISVFVTH -SKENQETNERIISDIAKAAWDFf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI00130D7E26 ---RLDKEIGGIEEQAKGRLGVALLDLKDRKLW-SHRGAETFPMQSVFKLPLAVAVLQQVE -AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLSELIRLAAGESDNTAADLMMREIGGP -QVVTRMLRDGGIEDMSVDRYERQFQPKALTDKRDAATPEASARFLEALAQGNWLRPAHNA -FLTKVITETKVGADRIKAGLPAGSTLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -ARADAPQREAALAEVARLAVS-- ->[subseq from] Beta-lactamase n=2 Tax=Fibrella TaxID=861914 RepID=I0KGH9_9BACT ---DMQAFMKKMGAEAKGRVGVAAAIVETGESI-AYAGTERFPMQSVYKLPIAMATLAAID -AGTIRRQKPITVGTGDYVGHSPLRDQHPSGAVSIDELLRYAVSESDGSASDVLLRLVGGA -SSVQSYLRTIGVTGVMVRNTERELGSADSVQYANWATPVEMVSLLRQLQLGRGLSDASRT -YLLKLMTDTATGPNRLKGQLPPGTLVAHKTGTSMTAATNDVGLITLPSGKHLAIAVFVSD -ARADQATRERVIAQITKQLWNRw ->[subseq from] Uncharacterized protein n=1 Tax=Stenotrophomonas pictorum JCM 9942 TaxID=1236960 RepID=A0A0R0A388_9GAMM ----LQQELDRLVAGFDGSVGAYVLDLRSGRSA-QVNGDSGFPMASTVKVPVAVHILALVD -EGRLGLQQQVLLEQGDIYPMGGPMDIHLSPGITVRDLLHMMLTVSDNNATDILIRLGGGP -AAVDARMRALGVQGIRVDRYIWEMLSLYNGDPRDTGTPADMAMLLRKIWNGGALKPATTA -VLKQILLDCRTGPGRLKGMLPEATPVAHKTGTVGD-VINDVGVVTLPGGGEVVVAVFLKS -GLGD-HARDRQIAQIARAAHDYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WNX8_9BACT --sALQNQIKEIAAEAKGKVGVTAVVLESGETVaSLNPQEHFPMQSVYKLPISMAVMKAVD -AGKVKLTDKVTISKSEFVGHSPIRDQHPNGALTVEELLRYALSESDGTASDVLMKLAGGP -AAVQA-LTELSIKDLIVLDTEQTFTQDKTAQYRNWATPEAAVALLRALHESRGVSESSQS -LLLKFMTESTPGAKRLKGMLPAGTPVAHKTGTSGTAATNDIGIITLKNGKHVAIALFVSD -SPADQVTREGVIAKIAKAVYD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B0XX73_9BACT ----LLAEIERLAPNSGGTVGVGAVHIETGRAV-WFNEDERFPMASTYKVPIAVQLLSRVD -RGEISLADMVELEPADIHPGSGTISNLFDDPLSLRNLLELMLLISDNSATDLTLTAAGGP -DAVNARMAELQVDGLSVDRPTSSLIGAFSTDARDTSTPRAMAHLLAMTWAGKALGSKNTE -VFKDVMLRVQTGTGRIKGVLPPGTPVGHKTGTIG-GTTNDVGYIYLPDGGHVITVVFVKD -SERSVPAREATIAQISRAIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI00093C0ACA ----LVAELRIIEAAGGGTLGVEIFNTVTGASV-GINQDRRFGHASSFKFSLAAMVLALDA -AGRIDADRQVRWSEADLMWVSPFTRERLSTGATLRELARATQITSDNTAANVLLRELGGP -AGLTAFWRSIGDEVSRLDRYEPEMNLVTAAEYRDTTTPAAMARTVAKIVYGDVLPEKERA -ELKGWMVATETGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGGPLTFACYFRA -RQEMLASGQETLARVGRII---- ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5405 TaxID=1864825 RepID=A0A2N7B7H1_9BACT --qRLQQELERMAKLAKGKVGVCALHLESGREI-RMNAKDRFPMASTMKVAVAVELLRKIE -TGELSYLTMTELQPSDLHPGSGTLETLFAKPLSLQNLMELMMVISDNSATDILIRLAGGT -RTVQNRLKALGIEGMSVDRNIIQLIATFDKDPRDTSTPEAMVQLLTQIYQARAVSVASRD -TLLAIMERCRGGQGRLKGYLPPETVVAHKTGTMGASATDDVGIITLPGDGHIAIAVFVGA -SQAPSELREQTIAQISRSVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas koreensis TaxID=266128 RepID=UPI0007105EEA ---ALQREAQRLVQGLEGEVGVSMIHLQTGRAV-HVNGQRAFPLASVMKLPVAVHILKLVD -EGQLTLGQTVTLTEADIYPMGGPMDLHLSAGISVRDLLHMMITVSDNNATDILLRVGGGT -AAVNTRMQQLGIDGIRIDRYIWELLAAWNADPRDTASTAAIATLLQQVWQGRVLSDGSTA -VLKQIMAQTRTGSGRLRGVLPPRTPVAHKTGTVGD-VINDAGVITLPDGKGEVVVAVLMQ -SSADTAARERTIADLARAAHDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. CECT 9293 TaxID=2675057 RepID=UPI00135DA0E5 --sTLDQKINSILKDKKATVGISVLGFENGFKY-NKNGNKRLPLLSVFKFHIALAVLNDVD -RGKLSLSQKILVKKTDLLDWSPFRNKYPNGNKSLQELLQYMVSNSDNNITDLLIRLIGGT -QSVQKFMDKMKVQDFTIKADERKMHEGFEFHYWNTSTTNSLNNLLKRFYDGKIVSKNSTS -FLMKTMLETTTGANKIVALLPKETKVAHRTGSSGKNAENDIGIITLPNGNHLALSVLVSD -SMESEVTNTRMVAEIAKIVYQHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Pedobacter oryzae TaxID=1122943 RepID=UPI00040C97DB --dSLREKIQQIISTSKATIGVSIIGRNKEDSI-SINGERRFPMQSVFKFHIALAILSQVD -KGKLSLDQKIKIEKKNLLPHSPLREKYPNGALPLAEIISYTVSNSDNVGCDALLRLLGGP -EAVEKYFLRKGFNDISIKINEEVMQNNWELQFQNWTTPKGANKVLEAYYHKKLLSPKSYD -FVWKEMRENESGKNRLKGKLPQGTVVAHKTGSSGTAAVNDIGIVFLPEGEYFFISVFVSN -SKEDFDTNERIITDISKAAWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium zhairuonensis TaxID=2493631 RepID=UPI001051DE53 ---DLRKELNQIIASKNATVGISVKSIEDKDTL-SINGNLNAPLMSVFKFHIALTVLNKVD -EGKLSLDQKVFIKKKDLHEWSPIRDDYPEGNLTLDKLLRYTVSHSDNNGCDLLIGLVGGT -KEIQKFINKLGIKDFVIKVNEKQMET-WKNLYVNTTTPLATTQLLEKFYKGEILKETTTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDVGIVKLPNGKHFILSVYLKE -ITETKENTEKIIADITKATWNYf ->[subseq from] Extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9M9P7_9FLAO ----LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDKKLPLLSVFKFHLACAVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD -FLMQIMLGTTTGTNKIVEQLPKSTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium hispalense TaxID=1453492 RepID=UPI000493577F --sALEQKINSIVKNKKATVGVSVLGFEDNFQY-GKNAEKKLPMQSVFKFHIAAAVLDYVD -HGKLSLDQKILLDKTNLLEWSPLREKYPQGNVPLREILEYTVAKSDNNGCDIMLKVLGGT -QNVQKFMDAKGVKGFQIKFNEAEMHKDWNAQYQNYSTASSATDVLKKFHDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIAIVTLPNGKHYAISVFVSN -STETDVVNCKMISDISKSVWDYf ->[subseq from] Beta-lactamase n=2 Tax=Halieaceae bacterium IMCC3088 TaxID=2518989 RepID=F3L4D6_9GAMM -------ALHTVTSGLVGVAGVAAQDMTTGAQI-FLNGDEPFPMASTYKIAIAMTLLAKVD -HGELNLTDMVDIDDSEWVYSQVIAANFIHQGLSIANLLEVMITQSDNTATDICLRLAGGP -SAVNQYLGQLGIDGMRVDRSTADLLREFEADPLDKSTPRAMLNLLTTLSSGRALSDESTR -LLMDTMMRTVTMPRRLSALLPKNTAIAHKTGTVG-GVANDVGYITLPNGRVFAIAVFTRG -SQSPPSDRERAIAEVARTLYDYf ->[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000DFF6FB4 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. ZY74 TaxID=2488634 RepID=A0A3N4PYY1_9BACT ---SIYRQIASIAAEAGGEVGVAALNFTTGDSL-RYLDTMRYPMHSVFKFPIAMAILHQVD -EGKLQLHQPVYINKSWLVPWSPLRDSFPNGDKPLSYLLGLMVSQSDNIACDILIDLAGGE -AAINDYVHGLGVQHINIAANEAKMASSWDVQFTNWAYPSAIIQLLDILNKGTALTKTSND -FLWKIMIATTTGPKRIKGLLPPDVVVAHKTGTSGTSATNDAGIIFMPGGEKLAITVFVTN -SKADEATREGVIAKITKLIYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Roseovarius aestuariivivens TaxID=1888910 RepID=UPI00108209A5 ---SVGAAIERVATKLAGRIGFAAQEIGGDEVI-AFNGDETFVMASTYKVAIAAAVLDRVD -KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP -AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDGGTATSAESRN -FLIDVMSRTRTGAGRLKGLLPRGTPVAHKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SVTSEADRDRAIAEVARSLFDYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A4V6IAS9_9FLAO ----LDEKINAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD -KGKFSTYQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD -FLMQIMLGTTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A345N8B3_PSEAI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHRTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Class A extended-spectrum beta-lactamase VEB-25 n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B9KH37_KLEPN ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHRTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. AtDHG13 TaxID=1938897 RepID=A0A318E2W6_9GAMM --dALQHSLEALAQRAPATLGIAVLDLSTGASP-RVNAEVAFPMMSVFKAPVAAAVLSRVD -EGTLSLQQLVSITRDQVQSGSPSVGTHFKGEFTLEQLLKAAVSESDNTAVNALLRTVGGP -DVVTEYFRAHGIEGMRVDMDEAGISRAFLKDPRNRTTPDAAITFLHKLVEGSLLSPASTQ -RLLALMKAQTI-PNRLRAGLPPGVRFADKTGTSGTAAFNDMGIITWPDGHKVLVAAFLMD -SATTAKERDQLFAEIARTVAT-- ->[subseq from] Beta-lactamase n=1 Tax=Aquimarina atlantica TaxID=1317122 RepID=A0A023BW58_9FLAO --eTLRQKIEGIINSKSAVVGVAINGMETKDTL-SINGQRHFPMQSVFKFPIALTILSEID -KGNLSLEQKIDIKKSELLPWSPIRKKYPEGALTIAEIMKYTVALSDNVGCDVLLKLLGKP -QAVENYFSKLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANKILATFYKNSLLSKKSHE -FVWNVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFIISVFITE -SAENFETNEKMISDISKATWDYf ->[subseq from] Class A extended-spectrum beta-lactamase CIA-3 n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=G9MB50_9FLAO ----LDEKISAVIKDKKATVGVSVLGFENAFKY-SKNGDEKLPLLSVFKFHLACAVLDMAD -KGKFSTYQKFLIKKSDLLEWSPLREKFPEGNLSLGEIITYTVAQSDNNTCDFLLRLIGGP -QVVQHFMDSKGAKDLQIKYNEDDMHRDWKNQYGNESSTNATVSLLKKFYDGKLLTKKSTD -FLMQIMLATTTGTNKIVEQLPKGTPVAHKTGSSGTVAENDMGIITLPNGKHYAIAVFVSN -STETEKVNTRMVSDISKIVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI00114C903B ---TFAKDIDQIENEYNNKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella humi TaxID=2068657 RepID=A0A2U2J5F6_9SPHN ----VTPALEALASRAPGQLGAAVLDLGTGEMK-GVNADKPMPMQSVFKLPLAIVVLDLAD -KGKLSLDEEVTLTRDQLSVHSPIADAFPEKTYTIEALMRAAVAQSDNSAADILLKRIGGP -EVVTRFFQDRGIGSFRLDRYEYELQPIYLADPRDRVSPADVVRILSMLAKGELLSPESTE -KLMDILESTSTGTDRLKAGVPDGATVYHKTGTGPASATNDVGIIELADGRRLAVAAFLAG -AELPPEGRAALIAEVARIAT--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium tenax TaxID=191577 RepID=UPI0004160309 ---ELRKELNGIISTKNATVGVSIKGIEDEDTL-SINGNMKMPMMSVFKFHIALAVLSEVD -KGKRNLKQKFFIKKEDLKKWSPMREEFPDGNVTLDQLLRYTVSHSDNNGCDILLKLIGGT -EAVQKFINKSGIKDFTIKMNEDQMRT-WENLYINTTTPIATTELLEKFYKGNILKKATTK -YLYQIMVECSRGTTWMKAGLPDGTELAHRTGISGTNAMNDIGIVKLPNGRHFILSIYLKN -ITESREDTEKIIADITKATWNYf ->[subseq from] Class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5Q8AMI5_ECOLX ------------------------------------------------------------- --------NASIILKNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDEQ--------------- ->[subseq from] Beta-lactamase n=1 Tax=Croceicoccus sp. TaxID=1927144 RepID=A0A2D6EBM8_9SPHN ----FRRKLFAVAPQSQGRIGVAALDLTTGQTV-SIEGDEPFPMASTSKIAIAATFLAGVD -AGKYSLFDRYPLMVPVASESSKVAPVRAGQTMTAETLIERMITRSDNQATDALLAVVGGP -QAVNAWARKAGLNRFRIDRDIATLVRSRHVDVRDSTPPEEMVELIAGLHQGKWLSPASRG -LLIGAMTRTVTGSSRIKAGLPSGVTFGHKTGTLNK-TASDVGFVTMPDGRVVVMAIYVTG -QSGP-AARNAKIAEITRTIYNGf ->[subseq from] Beta-lactamase n=1 Tax=Thioclava arenosa TaxID=1795308 RepID=A0A2A4CMU7_9RHOB ----VGAAIERVATKLAGHIGFAAQEIGGDDVI-AFNGDETFVMASTYKVAIAAAVLDRVD -RGELSLDQMVEVTPDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP -AAVTQYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLQLLLAIDSGAATSAESRD -FLVDVMSRTRTGAGRLKGLLPRGTPVGNKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VMD0_9GAMM -------NAAALEAASGGRLGICLVHPDHRQVM-AHRAREAFPTASTIKFALSAAVLAKSD -AGALSLDDRIPVREQDIRSGAPVSGRHVGKDITVRDLCRGSMVWSDNPAVNLLLPLVGGE -AGLQAFLREHGDTDTDPRGISE---------GRSTTTPLAMAHNLRRFVLDDALSRSSRL -QLADWLIENRTGDARIRAGVPEGWRVGDKTGGMQ-GVSNDIAILWPLRGAPWVLTLYLRD -SPLDAAGRNAVLRRATELAA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium aquaticum TaxID=452084 RepID=A0A0Q3HRQ5_9FLAO ----LEQKLNSITKDKNATVAVSVHSFEDNIKL-SINGDKKLPLLSVFKFHIALTVLNLVD -QKKLSLKQKILVTKGDLHEWSPFRKKYPNGNITLEELLQYMVSQSDNNITDLLIRLVGGT -QSVQNFMDKMKVKDFTIKADESKMHEGYEFHYLNTSTANSLNQLLKNFYDKKIISKSSTS -FLMKTMLETTTGANKIVALLPKETPVAHRTGSSGKNAENDIGIITLPNGKHIALSVLVSD -SMESEETNTKMVAEIAKVVYENf ->[subseq from] Beta-lactamase n=1 Tax=Francisella frigiditurris TaxID=1542390 RepID=A0A1J0KSL4_9GAMM ---QVQNKISKVQGKFGGKIGIYTIDRNNWKNF-KYNENFQFPICSVFKFLVVGAILKESM -ENPGLLDKKIKINEGDIVGYTPVTSKNINKSLSVKDLSKAAI-LSDNTATNLLINELGGL -KKLNEFIISLNDKDTIITANEPNVNNINLHDNFNKTSPKSIARDINKIAFDDVLDKRHQK -LFRKWLKENDTGKNRIAYSLPEGWQIGDKTGTCEYGSTNDVAILWPKGKKAIIMSILYTQ -ADKNAKPKDEIIQATSKIVLDY- ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. MYb7 TaxID=1827290 RepID=A0A2S8ZYC3_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFKY-NKNADKKLPMQSVFKFHIAVAVLNAVD -QGKLSLDQKIKLDHSNLLEWSPLRDQYAGKEIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAADALKKFYDGKLLSKKSTD -YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGSSGTGAENEIGIITLPNGKHYALAVFVSN -STETDTINCKMISDISREVWEYf ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter cerinus TaxID=38307 RepID=UPI000C074E83 -------QIASAEPREQEQSGWWALDLETNRTL-GENPDTHLPMCSTFKWLLAAATLSRTD -YGREHLGREIAFSRKDLISASPEVKAALAASLSVGELCAATVSLSDSTAANLLLKRLGGP -AALTHWLRDHHDPVTRLDRYETALNRVPMGDLRDTTTPRAMVSNLQNMLYGNNLSSASQA -QLLKWLLATTTGPKRMPAGLREGWRIGHKTGTWTRAASGDVAILLPPTGKPVLVAAYAAG -YSIPQSEKEGWFADIAHRAT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. AG363 TaxID=2183997 RepID=A0A420CUQ3_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAATVLNAID -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -QTVQKFMDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD -YLMQVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGEHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI001431C6C2 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPLAAAQTLNSILTSNEMNESNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000E67FF07 ---TFAKDIDQIENEYNTKVGIYGINTENGKVY-EHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter soli TaxID=1739690 RepID=UPI0013696168 ----FERQIAQLADGSAGRIGVAAIDLSTGREI-AVLGDQRFPMASTSKIAIAATYLEGVD -KGRWTLTREWPLMVPVSSRFSTATAPVVPGQMSARQLIDLMITRSSNPATDAMLAAVGGP -AAVNDWARRAGIANFNLTRDIATLVRATYVDIRDSATPRDMVKLLSGLYQGRWLSASSRQ -VLIGAMERCRTGTRRIPALMPERVTVAHKTGSLNN-TSSDVGILTAPDGRTIAVAIYVTG -QG-SKARREAKIASIARAIYDGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000787E9EA --kDLKNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNRVD -EGILKLDQKFFIKKEDLLSWSPIREEYPQGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -ETVQKFINQQGIKDFTIKVNEKEMSS-FEKCYLNTTTPLATTELLEKFYKGKVLKKETTK -YLYQVMVETSRGLNWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSIYLKN -IKEEMADTEKIISDISHAVWEYy ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T3C1_9BACT --dKLKTEIDSLVKSKNATVGVSIIANNFKDTI-NINENLHYPMQSVFKFPIALAVLSEVD -KGNLKLNQEIIIFSKDLLPWSPIREKFPDGTMTVADIIKYTMAQSDNNGCDILLRLLGGT -TAVEEFLSQHQITDISIKFNEEDMHKEWNIQFQNWATPIALTKLLAKFYVDNILSKESYE -FLWRVMSETTTGTDRLKGQLPQGIIIAHKTGTSGTAAINDIGIIILPNGNPIFISVLVSN -STEDHGVNEKIISDIAKKVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus halotolerans TaxID=260554 RepID=UPI000D47A4A0 -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D3QJP0_9BACT ---HLAREVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILTMVD -KGDLALTDMIEIEREDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA -EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEKSSS -LLIDIMYRCQTGEARLKGALPPGTQVAHKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE -SKPDNPAMEPVIANIARAIHDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=UPI0012654A25 --kDLRNKINEIISTKKATVGISLKGIEDKDTL-SINGNKETPMMSVFKFHIALAVLHQVD -KGRLKLDQKYFIKKEALLPWSPMRDEYPQGNLTLDQLLRFTVSHSDNNGCDILLNIIGGT -EVVQKFINQQGIKDFTIKLNEQEMSS-FDKCYINTTTPLATTELLEKFYKGKILKKETTK -YLYQVMVETSRGLTWMKAGLPIGTELAHRTGISGRAAMNDVGIIKLPNGKHIILSVYLKN -INEEMADTEKIIADISRAVWEYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR005 TaxID=1500288 RepID=UPI000646696F --sALEQKINSIIKDKKATVGISVLGIENDFKY-NKNSDKKLPMQSVFKFHIAAAVLDFVE -KGKLSLDQKIVLDKSNLLEWSPLRDKYPTGNIPLSEILELTVAKSDNNGCDIMLKLLGGP -KTVQKFMDSKGVKGFQIKYNEAEMHRNWNVQYENYSTTQSAVDVLKKFYEGKLLSRKSTD -YLMKVMLSTSTGLNKMVEQLPKSTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVSN -SIESDAVNCKIVSDISKAVWDHf ->[subseq from] Beta-lactamase n=4 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T2E7_9BACT --dKLKTEIDSLVKSKNATVGVSIIANNFKDTI-NINENLHYPMQSVFKFPIALAVLSEVD -KGNLKLNQEIIIFSKDLLPWSPIREKFPDGTMTVADIIKYTMAQSDNNGCDILLRLLGGT -TAVEEFLSQHQITDISIKFNEEDMHKEWNIQFQNWATPIALTKLLAKFYVDNILSKESYE -FLWRVMSETTTGTDRLKGQLPQGIIIAHKTGTSGTAAINDIGIIILPNGNPIFISVLVSN -STEDHGVNEKIISDIAKKVWDYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR460 TaxID=1500290 RepID=UPI0006489DAA ----LEQKINSIIKDKKATVGVSVMGFENGFKY-NKNAGKKLPMQSVFKFHIAAAVLDYVD -KGKLALDQKVLLDKSNLLEWSPLRDKYPNGDVPLSEILESTVARSDNNGCDIMLKLLGGP -QTVQKFMDSKGVKGFQIKYTEAAMHNDWNAQYENYSTMTSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGKNKLIEQLPKDTPVARKTGASGTGAENEIAIVTLPNGKHYAISVFVSN -STETDVVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. AG363 TaxID=2183997 RepID=A0A420CTJ8_9FLAO --kDLKNKINQIISTKNATVGISLKGIEDKDTL-SINGNKETPMLSVFKFHIALAVLNRVD -EGILKLDQKFFIKKEDLLPWSPIREEYPQGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -ETVQKFINKQGIKDFTIKVNEKEMSS-FEKCYLNTTTPLATTELLEKFYKGKVLKKETTK -YLYQVMVETSRGLTWMKAGLPVGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSIYLKN -IKEEMADTEKIISDISHAVWEYy ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf405 TaxID=1736367 RepID=A0A0Q6B1T2_9FLAO --sALDQKINSIIKDKKATVGISVLGFENGFTY-HKNGNKKLPMQSVFKFHIAATVLDNVD -KGKLSLDQKVSLNTSNLLEWSPLRDKYPNGNVPLSEILEFTLAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEVMHKDWNAQYENYSTTASAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGINKLIEQLPKNTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVSN -STETAEVNCKMISDISKTAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter dongtanensis TaxID=692370 RepID=A0A1B2AC19_9SPHN ---RLEAKLRLIEVAAGGRLGVAFVDPVQRLTL-GYRAGERFPMASTFKASLAALLLAKAD ---DVDADRVMRWTEADLQSYAPFAKERLATGATLRELAQAAVEASDNTAANLLLARLGGP -AALTAFWRAFGDDVSRLDDIEPQLNFVPQGDPRNTTTPAAMAGTIGRLLGESVLPVPSRA -SLRKWLAGATTGLTKVRAGVPSTWEAGDKTGNSGY-ARGDIGYVVGPASEPIAFAVYHQS -PVDAAAKVDEAFAEVGRTL---- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter confluentis TaxID=1849021 RepID=UPI00136C92A0 ---RLAAKLRIIEAASGGVLGVSVRHVGTGRTL-DYRADQRFAQCSSFKFSLAAMVLKMGQ -DGQLDLSEKLHWSRSELMATSPFTASRIDQGATVLELAENTQTYSDNTAANVLLARLGGP -AALTRFWRSLGDDVSRLDRTEPALNNVPPGEIRDTTSPAAMALTTEKILFGDVLSASNSA -LLQQWMADTRTGVRRVRAGLPADWRAGDKTGTSIGGIYVDIGFASPAGTQMLTFATYLRT -IREMDPASEDVLAQVGRVIAQ-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium indoltheticum TaxID=254 RepID=A0A3G6N4V0_9FLAO --sALAQKVDSIIKDKKATVGVSVLGFEDAFKY-NKNAETKLPMLSVFKFHIAATVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGTKYLYENYTTTNSLSQLYKSFYDGKILSEKSTK -LLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISNISKAVWDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Flavobacteriaceae bacterium CRH TaxID=1742859 RepID=A0A101CRX8_9FLAO --nQLREQLNQIIASKNATVGISIKGIEDKDTL-SINGNLKAPMMSVFKFHIALAVLNKVD -DGKLSLTQEIFIKKKDLHEWSPMQKEYPNGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT -KEVQKLINKQGIKDFVIKVNEEQMKT-WKNLYINTTTPLATTELLEKFFKGEVLKENTTK -YLYQIMIETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN -ITEKQEDTEKIIADIARATWDYf ->[subseq from] Class A beta-lactamase n=2 Tax=Agromyces fucosus TaxID=41985 RepID=A0A4Q2JV61_9MICO -hrRLSDAIAELEQATSVTIGVTAIWHDSRRAF-RYRGDQRFPMCSVFKTLAAGALVQARG -YDEAYWAGPIPFTSADVVGDSTKLDTT-TWTATPEQMADAALRFSDNTAGNLLLRELGGP -QAVTAFARSLGATRTRLDRPEPEVNEATPGDERDTSTPDDIAFLFQKLLIDQGAGALTTA -RLQEWMLRNTTSGKRILAGLTSPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT -DRADAPSNHDVLADVTRLVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A0U5B2K6_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLLYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E9UZV8_9SPHN --qDLAARISEXETASGGRLGLALHSPDKGLVX-AYRGDERFAMCSTFKLALAAXTLDXPG -----LREKRLXFGAGDILSYAPYAKERASSGMGGLEAAHHAVTLSDNTAAXLLLAEVGGP -DGFTRWLRSMGDETTRLDRNEPALNENAPGDPRDTTTPTAHADLVGTLLWGDRHAQADRA -LLQEWLVETTTGMNRLRAGLPGEWRAGDKTGTCGQGEVNDIAMFETPDGSRYILAAYLDR -ADGSASDAEARLAEAARAXAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=UPI0011595B45 --qTLRQQIAGIAGNISGKVGVYAEVLETKDTV-SFNRDGHFPMQSVYKFPIAMAILHQVD -RRQFRLDQSIHVAKSDLIPASLIRDLHPEGNMALSELISHNIRASDGSACDVLLRLLGGT -AKADAYVHSLGVKQMVIATTEQVQVPNEMIQYKNWATPMAMTQLLKIFYREPVLSDSSKN -YLMDLMITSKPGAKRLKGLLPAGTVVAHKTGTSGTRATNDVGIITLPNGHHLAITVFVSD -SKASEEEREGAIAKIAKAAYDHw ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=A0A316WK03_9FLAO ----LEQKIDSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIVLNKSNLLEWSPLRDKYPEGIIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAADVLKKFYDGKLLSKKSTE -YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISKEVWQYf ->[subseq from] Beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A411F1X5_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTSGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. ZNC0032 TaxID=1339244 RepID=UPI00068C3062 --dKLDKAIEGIEQASKGRLGVALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGKFRLDQPITVTRKDFSLHSPLAKAFKGERYPLRELIRLAAGESDNTAADLLMREIGGP -QVVTRMLRDGGIQGMSIDRYERQFQPNALKDKRDASTPEASAQFLEAFARGNWLRPAHTA -FIEKIVAESKVGTDRLKAGLPAGTRFAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADADERATALADVARLAVS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=G5D8T5_ECOLX ------------------------------------------------------------N -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKP---------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium rhizosphaerae TaxID=395937 RepID=A0A3D9D4B0_9FLAO --eRLRKEIQQIITSKNATVGISIKNIEDRDTL-SINGNSMMPMMSVFKFHIALAVLDQVD -KGKLKLNQKFFIKKEDLLPWSPIQEEFPNGNLTLDQLLKYTVSHSDNNGCDILLRILGGT -EPVQKFINQQGIKDFIIQVNEQQMS-NWDNLYLNVTTPIATTALLEKFYNGKVLKENTSQ -YLYRIMTETSRGLTWMKAGLPDHTELAHRTGISSRAAMNDVGIFKLPNGKHIILSVYLKN -ITEERTDTEKLIADIARATYNYy ->[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000DFEBF5A ---TFAKDIDQIENEYNTKVGIYGINTEKGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xixiisoli TaxID=1476466 RepID=UPI00136EBFD7 --sALEQQIAALAEGSSGRIGVAAIDLSTGQEV-AILGDQRFPMASTSKIAIAATFLEGVD -QGKWSLSSEFPLMVPIRSAFSTTIAPVRQGELTAQTLIDMMITRSSNPATDALLAAVGGP -SAVNDWARRAGINEFQLSRDIATLVRAVSIDVRDSSTPRAMVQLLTGLYQGQWLSSASRH -VVISAMERCRTGTRRIPALMPGGVTVAHKTGSLNN-TSSDIGIITAPDGRSIAVAIYVTG -QG-TRDRREARIANIARAIYDGy ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. CH21 TaxID=713556 RepID=A0A4Q1EU35_9FLAO ----LEQKISTILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNVID -QGKLSLDQKIKLDQSNLLEWSPLRDKYPGGNVPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAVDALKKFYDGKLLSKKSTD -YLMKVMWSTSTGLNKMVEQLPKNTPVAKKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -STETDAINCRMISDISREVWEYf ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. 1_F178 TaxID=2258962 RepID=A0A3D9C4X2_9FLAO --sTLEQKINSITKGKQATVGVSVLGFENNFKY-SQNGDKRLAMMSVFKFHIACAALDLVD -QGKLSLDQKIFIKKSDLYEWSPYRVKHPEGNATLNEIIDYTVALSDNNLCDLLIGLTGGT -QAIQKFMNSKGIKDFQIKYSEHGMANGWDSLYENYTTTSSTVNLLKKFYDGKLLSKKSTD -YLMQIMLGTKTGANKIVEQLPKGTPAAHKTGSSGRKAENDMGIITLPSGKHYAIAIYVSN -SKESETENCKIISDISKVVWDNf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. 1_F178 TaxID=2258962 RepID=A0A3D9C1F4_9FLAO --qDLRNKIKTIISTKNATVGISVKGIEDHDTL-SINGNKEMPMLSVFKFHIALAVLNQVD -KGKLKLDQKFFIKKEDLLPWSPIREEYKEGDLTLDQLLRYTVSHSDNNGCDILLKIIGGA -PVVQKFINQQGIKDFTVKLNEQQMNTF-ESYFINTSTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIAKLPNGKHFILSVYLKN -INEEMKDTEKIIADIGSAVWEYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sporocytophaga myxococcoides TaxID=153721 RepID=UPI00040372CC --eSLRSDIEALLSTKKAKVGVSIMGDNLRDTL-SINGDQHFPMQSVFKFHIALTVLSQIQ -QGKFSLDQLIKINEDQMLPYSPLREKYPKGVLKISEILEYTVSQSDNVGCDVLLKLIGGP -QVVENFIQEKGFKDFSVKINEEVMQSNWDLQFKNWTTPKTSNQILVFFYNNDNLSPVHHD -FIWTIMKQTETGKNRLKGKLPKGTVVAHKTGWSGTAAVNDIGIIFLPNGRHYFISVFVTD -SKEDTAASEKIIADISKMAWEYf ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. HMWF028 TaxID=2056862 RepID=A0A2R7MVQ8_9FLAO ----LEPKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNSVD -QGQLSLDQKIKLDTSNLLEWSPLRDKYPEGNVPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSVADVLKKFYDGKLLSKKSTD -YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCKMISDISREVWEYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0D5C9G4_KLEPN ---------------------------------------------------AAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELIAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIG------------------ ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=UPI0012643E6A ----LEQKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIVLNKSNLLEWSPLRDKYPEGSIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALTVFVSN -SMETDAVNCRMISDISKEVWQYf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A126G805_PSEAI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTAGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0H4IS07_PSEAI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTAGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium indoltheticum TaxID=254 RepID=A0A381FFG2_9FLAO --sALAQKVDSIIKDKKATVGVSVLGFEDAFKY-NKNAETKLPMLSVFKFHIAATVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKSFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISNISKAVWDHf ->[subseq from] Beta-lactamase n=2 Tax=Enterobacteriaceae TaxID=543 RepID=M4QST3_ECOLX ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTAGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D1CB9B --qRLYDELERISSLAKGKVGICALHLESGKQI-GLNLQERFPMASTVKVAIAVQLFTLIE -KGQLSLTTMTELQPSDLHPGSGTLETLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -DAVQKRVKALGINGMSVDRTIIQLIAKIKNDPRDTSTPEAMVDLLTQIYQAKAISPDSRA -LLLGVMERCRGGQARLKGFLPPSTVVAHKTGSLYGSATDDVGIITLPGDGHIAIAVFVGD -SPQPLAEREQTIAHAARAIYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina megaterium TaxID=1443666 RepID=UPI00046EAE13 --eTLRQKIEDIINSKNAVVGVAINGMETKDTL-SINGQKHFPMQSVFKFPIALTILSEID -KDNLSLEQKIDIKKSELLPWSPIRKKYPEGGLTVAEIIKYTVALSDNVGCDVLLKLLGKP -QVVENYFSNLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANKILETFYTNSLLSKESHE -FVWSVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFTISVFITE -SAESFETNEKMISDISKVTWDYf ->[subseq from] Beta-lactamase class A n=2 Tax=Chryseobacterium carnipullorum TaxID=1124835 RepID=A0A1M7HPI6_9FLAO --kQLKKDLQQIISTKNATFGISVKGIEDKDTL-SINGNKRMPMMSVFKFHIALAVLDQVD -KGKLKLNQKFFIKKEELHSWSPIRDEFPEGNLTLDQLLRYTVSHSDNNGCDILLEIIGGT -QTVQKFINKKGIKDFTIRFNEQQMSGE--NLYINTTTPIATTELLEKFYKGKVLKKATTR -YLYTIMVETSRGLTWMKAGLPEGTELAHRTGISNRAAMNDVGIVKLPNGKHFILSIYLKD -ITEDRVVTEKTIADIARAVWEYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0201 TaxID=2487065 RepID=A0A3G6MHT1_9FLAO ----LDQKINSIIKDKKATVGVSVLGFENGFKY-NKNGEKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKILLNKSNLLEWSPLRDKYKDTNVPLSEIIDQTVAMSDNNGCDILLKLIGGT -QTVQKFMDSKGVTGFQIKYNEEEMHSDWSFQYKNYSMTNSAVQVLKKFYDGKLLSKKSTD -YLMKVMLGTKTGLNKMVEQLPKDTPVARKTGSSGTGAENEIGIVTLPNGKHYAIALFVSN -STETDAVNCKIISDISKAFWDHf ->[subseq from] Beta-lactamase n=1 Tax=Pararheinheimera tangshanensis TaxID=400153 RepID=A0A5C8LZH2_9GAMM ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSLSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSASSQA -LLWKWMVETTTGPERLKGLLPADTVVAHKTGYSGTAATNDIGIILLPDGRSLLVAVFVKD -SAESTRTNEAIIAQVAQAAYQ-- ->[subseq from] Beta-lactamase n=3 Tax=Kozakia baliensis TaxID=153496 RepID=A0A1D8UXU2_9PROT -----KQLISGIERKLGGRVGVSAVDTQTRLIL-QWRGSERFVMHSVFKWLLSAYLLHCSD -TGSRPLQTRVVIKTSSIVGHSDQTKPFVGTAITLETLCLWMMSTSDNGAANTLLDVIGGP -DVLTAWLRSLGDITTRQDTYEPGPTEG-SIDPRNTTTPNAMLALTQKIWLGGVLSPRSRE -TLLAWLRGSAIGGHRLRAGVPSSWVEGDRTGTGDPGVANDVAIFWPDGRRPILVSSFLEG -SANDLARLEDAQASIGRILANLf ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus edaphicus TaxID=1955013 RepID=A0A2C6WM18_9STAP ----FAKDIDKIEHEYDTTVGVYGINTENGKEY-KHNANERFAFASTYKAIASGILLNNYS ---QVDLNKKVQINQADIVANSPVTEQHIGKTMSLKALIKASMLKSDNTANNKIIEELGGA -TGLKHELELLGDYVSAPQRLEPELNYFDPHSTADTTTPQAAATTLKHILTSNENNKSNVA -LLKQTMIENETGDTLIKAGVPKSYTVGDKSGQGTYATRNDLAFIYPKNQKPIILAIYSKQ -DQKDGKPNDKVISDSAKAVIKH- ->[subseq from] Beta-lactamase class A n=2 Tax=Porphyrobacter sp. LM 6 TaxID=1896196 RepID=A0A1D7NJ85_9SPHN ----LAAELRIIEAAGNGTLGVELYNTVTGLSV-GINRSMRFGHASSFKFSLAALLLARAA -AGTIDADKRVTWTEAEMLEYAPFTRERIATGATLRELAEATQTTSDNPAANILLRELGGP -AALTAFWRSIGDDVSRVDRYEPEMNIVPPAEFRDTTTPAAMARTVAAIIYGNVLPEAERT -MLKGWMVATETGLKRVRAGLPEGWVAGDKTGTSGDGNYIDIGFAEGPKGPPITFACYFRA -RQDDMQARAQLLSRVGRV----- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Mucilaginibacter sp. OK283 TaxID=1881049 RepID=A0A1H8T334_9SPHI --dRLREKIAEIAKDAKGTIGVSVLNLETGDTL-TYNGYLRQPMQSVMKFPIAITVLHEID -EGKFTLDQLVRLDKSDLFKYSPLQDKYPAANVSIRELLSYMVSLSDNVACDKLLKVLGGT -DAVEAYIHHIGIKNFSIKASEYQMAQAWDVQFTDWVMASELTHLLNVAFKPNFLSAASHT -YLWKIMQETSTGPNQIKGLLPVGTIVYHKTGRSGTNATNDTGIITLPNGNHLAIAILVTN -SPVDLKARELVIARIAKAAYD-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium indoltheticum TaxID=254 RepID=A0A381FCX1_9FLAO --sALAQKVDSIIKDKKATVGVSVLGFEDAFKY-NKNAETKLPMLSVFKFHIAATVLDLVD -KGKLSLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIINYTVAWSDNNGCDVLLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKSFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEMNCKMISNISKAVWDHf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X6Z9_9BACT ---ALETELRRLAATLPGTVGIAVHHVGTGRLV-TVDAHRAFPMASVFKLPVAIAVLRRVQ -TGGLTLETPITIAPEAYYPYSPLRDAKNRAEVTVRDLVETMMVDSDNTAVDVLMARMGGA -DAVNAELRAAGVPDVSVHRTEGEVMAKFLADSRDTATPTALANLLARLDRGEVLDAERTK -ILVGMLDRNKTGGRRFRAGLPAGVRIGDKTGTNPVGTYNDAALVTLPSGARIALVVMTRE -AGDTGAAAEQLMASVARTVYAHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. s2p32 TaxID=1367558 RepID=A0A0B5EAU4_9PSED ----------------------------TVKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEA---------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. AU58 TaxID=1874112 RepID=UPI000D6DEB7F --eTLRQEIENIINSKNAVVGVAINGMETTDTL-SINGQRHFPMQSVFKFPIALTILSEID -KGNLSLEQKIDIKKSELLPWSPIRKKYPEGGLTVAEIMKYTVALSDNVGCDVLLKLLGEP -QTVENYFSNLGFKDFSVKINEETMQNNWDLQFLNWTTPKETNKILATFYKNSLLSKESHE -FVWSVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFTISVFITE -SVESFETNEKMISDISKVTWDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacteriales bacterium 50-39 TaxID=1895841 RepID=A0A1M3H3G7_9SPHI --nALQDSLGTIAKDARGIVGVSLHYKASGRRI-SLHGMEHFPMQSVFKFPLALKILHDVD -NGRFSLDQMIHIDQKDWAPWSPLRDSLNGQTIPLQTLLRYTVSYSDNSGCDILFRLTGGT -RIVNDFIHHTGVKDIAIVATETEMARAWNVQYGNWCTPDAMTALLELFIDGKILKPATTK -ILMQFMINTSTGPGRLKGLLPPGIPLAHKTGTSNTAATNDVGIITLPDGKPLIISVFVKD -AAADEPTRERVIARIAAAAYK-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium camelliae TaxID=1265445 RepID=UPI000C1C926B ----LNQKIQSIISNKKATVGISVLGFENGFAY-HKNADQKLPMQSVFKFHIAVAVLNIVD -QGKLSLDQKIPLNASNLLKWSPLRDRYPDGNVPVSEILEMTVAKSDNNGCDILLNLLGGT -DTVQKFMDSKGVKDFQIRYSEAQMHKDWNAQYSNYTTAESATDVLKKFYDGKLLSEKSTA -YLMKIMLSTSTGMNKIVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGNHYAIAVLVSD -STESDAVNCRMISDISKAVWD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium timonianum TaxID=1805473 RepID=UPI00083B9EB5 --qDLKSKISTIISTKNATVGISLKGIEDKDTL-SINGNKTMPMLSVFKFHIALAVLSQVD -QGKLKLNQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLKIVGGA -PVVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTNLLERFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISGRAAMNDVGIIKLPNGKHFILSVYLKN -INEEMKDTEKIIADIGTAVWEYy ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. SLTY TaxID=2683262 RepID=UPI001412E544 -----------AERAAPARLEVAVQNIEGGEMW-ARNAVQAFPMQSVFKAPLGAAVLAEVD -AGRLSLDEVLTLEDMDLSPYSPIAAAWPGRAYTVGELLERAVSDSDNTAADVLMRRIGGP -GVLKAWMVDNGITGIRVDRYERELQTAYMEDPRDTATASGALGFLNKLSSGQLLSPASTT -RLLKLMTDTPRGDTRLKAGLPPGATLAHKPGSSGTAATNDIGIVTLKDGRKYAVVVFLSG -STADQAAQDAIIADAMRIIAR-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter xanthus TaxID=1784712 RepID=A0A3A1P9H0_9SPHN ----LARQIAQLADGSSGRIGVAAIDLSTGREI-SVLGDQRFPMASTSKIAIAATYMEGVE -QGKWSLSSEFPLLWSVRSTFSTATAPVRKGEMSAAQLIDLMITRSSNPATDALLAAVGGP -QAVNDWMRRAGLEGFQLTRDIATLVRAQHIDLRDSATPQTMVALLTGLYQGQWLSAESRS -VILDAMARCRTGARRIRGQMPGDVSVAHKTGSLNN-TSSDIGIITAPDGRSYVVAIYVTG -QG-SRGNREQRIASIARAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6S9V5_SPHSX ----LRRAVTRFAPATPGHLGVAAIDLESGATL-SIEGDARFPMASTVKIAVAAAFLHQVE -QGRHRLDEMFTLDETMRARSEGITETLPHPGLSALNLLELMLTVSDNTAADMLIGAVGGP -QAVTDWLKASGIEGQRADRSIARLILAFDADPRDSSTPLAMATLLARLHQGKLLSPDHTR -LLFEIMARCKTGKPRVIALLPPDTPWAHKTGTLA-GISNDVGVLTLPNGHHLVVALFAYG -IA-DAAARNRMLADVGRLLYDGf ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A357BCM8_9FLAO --qSLKSNLESIIKDKNATIGVSVWNLEKGEKT-SVNGDSNLPMMSVFKLHIAMTILDLVD -GGTLKLNQKIKFSKSELMQWSPMRDKYPNGGIPLSEMIKYVVAQSDNNTCDILLNKIGGL -KTVENYIHKIGVTDFWAVANEKMMHKVDGAIYKNLTTANASNLLLTKLYTESVLKKNSKD -FLIKIMEETSTGAKRLKGNLPENTVVAHKTGTSGTAATNDIGVISLPNSEHLVISVFVTD -SFENDQTNEKIIADVAKASFDYy ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=UPI00088C99BC --sSLEQKINSITKGKQATVGVSVLGFENNFKY-SQNGDKKLAMMSVFKFHIACAALDLVD -KGKLSLDQKVFIKKSELYNWSPFKKKYPEGNIPLSEVIDYTVALSDNNLCDILIELVGGT -QAVQKFMNSKGIKDFQIKHSERGMASGWDSLYENYTTTHSTVQLLKQFYDGKLLSKKSTD -YLMKTMLGTKTGTNKIIEQLPKGTPAAHKTGSSGTIAENDMGIITLPNGKHYAIAVYVSN -SKESEAENCKIISNISKAVWDNf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD74_KLEOX ---------------------------------------GRFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDHY--------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Oxalobacter formigenes TaxID=847 RepID=C3X3G3_OXAFO ---ALQAKVDAIVKQTQAEVGVAIESGGSAVKA-AHNADKPFPMQSVVKFPVALAVLDSVD -KGRLNLDDPVFLAPSDLLPHSPLREKYPEANIPLREILSDTITLSDNNGCDILLRLLGGP -QAVDRYIKGLGITGMEIGATEADMHRDPEKQFRNTATPAAANRLLRLFYRKKLLKPSSQE -LLWKLMGDTLTGPGRLRDPLPAGTALIHKTGTGAGMSVNDIGIIMLPDGRPVLISVFISE -AKDSILETEKTIAALSRAAWE-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. Gsoil 183 TaxID=1807141 RepID=A0A5D8ZVV7_9FLAO ----LEQKIHSILKNKKATVGVSVLGFENGFKY-DKNSDKKLPMQSVFKFHITAAVLNSVD -QGKLSLDQKIVLNQSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMNSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYAIAVFVSN -SMETDAVNCRMISDISKEVWEYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=UPI0012912D4F ----LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID -KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP -QVVESYFAKKGFKNISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD -FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPSGEYFVISVFVTH -SKENQETNERIISDIAKAAWDFf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium joostei TaxID=112234 RepID=A0A1N7HXD5_9FLAO --qDLRNKINTITSTKNATVGISVKGIEDKDTL-SINGNKETPLMSVFKFHIALAVLNRVD -KGKLKLNQKFFIKKEDLMPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLNIIGGT -DSVQKFINQQGIKDFTIKVNEQQMSS-FDKFYLNTTTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISSRAAMNDVGIVKLTNGKHFILSVYLKN -INEEMAVTEKIIADISHAVWEYy ->[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=A0A271J5B7_9BACT ---ALADEVERLAAPAEGRVGVGIALLGSDEAV--VVGEGRHPMQSVFKLPLGMAVLAAVD -RGELSLDRRVAVTLADFVSHSPIRDRHPDGVLSVGELLGAAAGGSDGTAADVLLDLLGGP -AEVEGFLRGIGVEGVDVAVTEKDMGRDYDAQYRNGATPAGALALLRALHAGRGLSQESRT -LLLRVLTETTTGPNRLRGRLPEGTPVAHKTGTSRTAATNDVGLVTLPDGRRLAVAVFVSD -SPADDATRERVIADVARAAYDAw ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000254AF75 ---TFAKDIDQIENEYNTKVGIYGINTEKGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NSLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYTTRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma endophyticum TaxID=662367 RepID=A0A1I1Q3U2_9BACT --qRLQQELERIAKLAKGKVGVCAVHLESGKQV-SLNLQERFAMASTIKVAIAVQLFTKIE -KGELSLSTMTELKPSDLHPGSGTLDVLFAKPLSVENLLELMMVISDNSATDILIRLAGGT -EAVQNRLKTLGIQGMSVDRTIIQLLAKFKYDLRDTSTPEAMVNLLTQIYRGKAITPASRD -TLLAVMQRCRGGLNRLKGYLPPETIIAHKTGSLDGNATDDVGIITLPGDGHIAIAVFVGP -SPQPLDVREQTIAHVSRLIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Brucella melitensis TaxID=29459 RepID=UPI000C05D189 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGEL------- ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6MJ04_9BACT ---HLAXEVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILTMVD -KGDLALTDMIEIEREDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA -EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEKSSS -LLIDIMYRCQTGEARLKGALPPGTQVAHKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE -SKPDNPAMEPVIANIARAIHDYf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus nepalensis TaxID=214473 RepID=A0A291JNQ7_9STAP ----SAKTFEQIEQDNDTIVGVYGVNTANGKHI-QHRSDERFAFASTYKAIASGILLQNTA ---TSTLNKKIDIKKDDIVANSPVTEKYVGSQMTLKALIQASMLQSDNTANNKIINEIGGI -KGFHEELKQLEDNISNPQRLEPELNLYDPTSTADTTTPKAAAMTLKHILTNEDMSKANRN -LLKNVMIHNETGDTLIKAGVSKQAVVGDKSGQGTYGTRNDLAFIYPKNQEPIVLAIYTKK -DGKDAKPNDKVIQMATKTAME-- ->[subseq from] Beta-lactamase n=2 Tax=Firmicutes TaxID=1239 RepID=A0A380GQT3_9STAP ----SAKTFEQIEQDNDTIVGVYGVNTANGKHI-QHRSDERFAFASTYKAIASGILLQNTA ---TSTLNKKIDIKKDDIVANSPVTEKYVGSQMTLKALIQASMLQSDNTANNKIINEIGGI -KGFHEELKQLEDNISNPQRLEPELNLYDPTSTADTTTPKAAAMTLKHILTNEDMSKANRN -LLKNVMIHNETGDTLIKAGVSKQAVVGDKSGQGTYGTRNDLAFIYPKNQEPIVLAIYTKK -DGKDAKPNDKVIQMATKTAME-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E6RZ35_9SPHN -----SATFRILERALGGRLGVAFHAPARHAHI-AYRGDERFPMCSTFKTSLAAQVLSLGE -DGTLDLSERVTWTADDLIFHTPFTGERVAQGATLSELAHAAQTVSDNLAANLLLDRVGGP -AGLTAFWRRLGDETSRLDRMETAVNFVPEGDVRDTTTPVAMARTLAKMLATNPLAAPRRR -ELRQWMIESTTGLKRVRAGLPEDWVAGDKTGNSGY-LRGNIGFALDPSEAPTFFAVYHQS -PVIDGQRVDAAFAQVGRLLA--- ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter sp. DsW_058 TaxID=1511210 RepID=UPI000A37660C ------SQIASAEPREQEQSGWWALDLETNRTL-GENPDMHLPMCSTFKWLLAAATLSRTD -YGREHLGREIAFSRKDLIAASPAVKDALAASLSVGELCAATVSLSDSTAANLLLKRLGGP -AALTHWLRDHHDPVTRVDRYETALNRVPMGDLRDTTTPRAMVSNLQNTLYGNNLSSASQA -QLLKWLLATTTGPKRMPAGLRDGWRIGHKTGTWTRAASGDVAILLPPKGKPVLVAAYAAG -YSIAQSEKEGWFADIAHRAT--- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter longus TaxID=1044 RepID=A0A074MSA0_ERYLO ----YAAMLRQIEGEFGGTLGAEFVDVTSGQAV-GLNSDVRFGHCSSFKLSLAAKILQRDV -SGEDSAERRVTWSEDDLMSVSPFTTRTLSQGATLRELAEATQKYSDNAAANILLREIGGP -AALTAFWRSLGDDVSRLDRYEPTLNLVPPTEVRDTTTPAAMARTVAKLVYGDALPEADRA -TLRQWMVDTPTGLDRVRKGLPEEWLAGDKTGTGLGGIYIDIGFVQPPERGAMTYAAYYRP -AGTDNTYD--------------- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. KBW03 TaxID=2153362 RepID=A0A3N7AXZ5_9FLAO --kDLRNKINEIISTKKATVGISLKGIEDKDTL-SINGNKETPMMSVFKFHIALAVLHQVD -KGKLKLDQKFFIKKEALLPWSPMRDEYPQGNLTLDQLLRFTVSHSDNNGCDILLNIIGGT -EVVQKFINQQGIKDFTIKLNEQEMSS-FDKYYINTTTPLATTELLEKFYKGKILKKETTK -YLYQVMVETSRGLTWMKAGLPTGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSVYLKN -INEEMADTEKIIADISRAVWEY- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium piscium TaxID=333702 RepID=A0A3D9BN89_9FLAO ----LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNAETKLPMLSVFKFHIAATVLDLVD -KGKLSLGQKILIKKGDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGT -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISDISKAVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 1335 TaxID=2183928 RepID=A0A3D9P5C3_9FLAO ----LEQKINSIIKDKKATVGVSVLGFENGFKY-NKNSEKKLPMQSVFKFHIATAVLDFVD -KGKLSLDQKILLNKSNLLEWSPLRDKYPNGNVPLSEILEYTVAKSDNNGCDILLKLVGGP -HVVQKFMDSKRVTGFQIKYNEAEMHKDWNVQYENYSTTNSAVQILKKFYDGKLLSKKSTD -YLMKIMLSTSTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIVTLPNGKHYAISVFVSN -SMESDAVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alcaligenaceae bacterium TaxID=2021368 RepID=A0A4Q3ZNF4_9BURK -----------------------------------------------------AHVLKRVD -EGQEKLDRPLSYSADDLLTYAPVTRANVTKKMSVSELAAAAVQVSDNTAANLLFRTQGGP -TGLTQFLRNLGDSITRSDRIEPELNTA--SGDADTTTPKAMSETLRTLFEKETLQPSSLA -LLKGWMLTNTTSAHRLKAGLPANWKVADKTGTGGQGNVNDVGIVYTPDGAAIYVAVFISE -SKKPTDELEAAIADVAREI---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD70_KLEOX ---------------------------------------GRFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDH---------------------------------------------- ------------------------ ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CBTAP 102 TaxID=2135644 RepID=UPI000D751195 --sALDQKINSIIKDKKATVGVSVLSFESNFKY-SKNGDKKLPLLSVFKFHLASTVLDMAD -KGKFSTDQKFLIKKSDLLEWSPLREKYPEGNLSLGEIIKYTVAQSDNNTCDFLLRLIGGP -KVVQQFMDSKGVKDLQIKYTEDDMHKDWKNQYGNESSTNSTVVLLKKFYDGKLLSKKSTD -FLMQIMLATTTGTNKIVEQLPKRTPVAHKKGSSGTVAENDMGIITLPNGKHYAIAIFVSN -STETERVNTRMVSDISKIVWDNf ->[subseq from] Serine hydrolase n=1 Tax=Chelatococcus sp. TaxID=1953771 RepID=A0A2W6XX53_9RHIZ ---ALDREIARIERDAKGRLGVALIDLKDRESW-SHRGAEPFPMQSVFKLPLAVAVLQAVE -AGKLRLDQPITITRKDVSLHSPIAERFKGDSYPLRELLRLSTAESDNTAADLLMRLVGGP -EAVTAMLKQGDVAGLSIDRYERVFQPASLTDRRDSATPDGSAAFLEALAKGNWLRPAHTA -LLVKMATETKSGPQRLIAGLPKGARLAHKTGLGPNHATNDIGIVTLPNGRVFAIAVYLAG -SQATATEREAAHAAVARAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000A524614 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNNLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI00037D8305 --qRLERELDRIATLAKGKVGICALHLESGKQV-SLNVQERFPMASTVKVAIAVQLFTLIE -QGKLSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLVGGT -EAVQKRINALGIQGMSIDRTIIQLLAKLATDPRDTSTPEAMVNLLTQIYRGTALKPESRA -LLLGVMERCRGGAARLKGYLPPNTVIAHKTGSLNGIATDDVGIITLPDEGHIAIAVFVGD -SPMPLADREQVIAQSARAIYDFf ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter frateurii TaxID=38308 RepID=UPI000C0784DD ------ARLRAIEQSAGGRLGAFVLDTGSGRSF-GWRMDERFCHCSTFKLSLAAMVLREND -AGRLDLSETLAVSRADIVAYSPVVEENLAKGLSFLTLAQAVQITSDNAAANVLLRRFGGP -EAVTRFWREIGDSTSRLDGYEPSINVIPPGTDKNSTTPRIMAETVRKIVLGNVLGTANRE -RLQGWMASTKSGLNRIRGGIPSSWGGFDKTGTGMGNKTNDLAVLIPPDHSPLIVTGYFEN -PADVRPADEAVLKALGEVAV--- ->[subseq from] class A beta-lactamase n=1 Tax=Lutibacter sp. SG786 TaxID=2587130 RepID=UPI00141F2BDC ---HLRDTLAQLAERAPGTLGVTVVDLETHDRT-RINADRGYPMMSVFKAPVAAAVLAEVD -AGRVALDQEVTIDRKDVVGGSPSIGAHFAGRFTVDRLLVAAVSESDNTAVDALIRLLGGP -AVVTRYLRDHGIDGMRVDLSEGDVSHAFMADARNTTTPDAAADFLEKLSRGKLLSADSTQ -RLLRLMYDQTV-PNRMRAGLPPDLRFADKCGTSYTAAFNDIGIVTWPDGHTVVVAAFLTG -SRADANTRNALFADIARAVA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. CH25 TaxID=713559 RepID=A0A4Q1FNY6_9FLAO --qDLRSKINTIISTKNATVGISVKGIEDKDTL-SINGNKEMPMLSVFKFHIALSVLNQVD -KGKLKLNQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLRIVGGA -PVVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSVYLKN -INEEMKDTEKIIADIGTAVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=A0A2T4LTS6_9STAP ----AAKSFDQIEQDNDTIVGVYGINTANGKVI-QHRSDERFAFASTYKAISSGILLQNTP ---TSELNKKITISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI -KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKRAATTLNHLLASENMSRPNLE -LLKHTMIHNETGDTLIKAGMSKDDVVGDKSGQGTYGSRNDLAFVYPKNQKPIILAIYTKK -TDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Beta-lactamase n=2 Tax=Chryseobacterium koreense TaxID=232216 RepID=A0A0J7IXK9_9FLAO --qSLRNEISKLTKGKNATVAVAVKGIDFPVEFnNENAGKKLPMQSVFKFHIALAVLDWVD -QGKLALDQKVFINKSELLPWSPIREKNPEGNMPISELIEYAVAMSDNVGCDVLLRLIGGP -KTVNDFLISKGMKDTQIVYNEEVMQSDWKNQYENYTTMKSSNTLLKDFYQGKIISKESTE -FLLGVLYRTSTGTNKIVEQLPKSAKVAHKTGSSGTGAENDIAIITLPNGKTYALSIFVSD -SMESWETNCKIISNISKAVYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000D1FB0C0 ---TFAKDIEQIENEYNTKVGIYGINTENGKVY-EHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKALIKTSMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Class A beta-lactamase n=1 Tax=Francisella endosymbiont of Amblyomma maculatum TaxID=255919 RepID=A0A1E7UB04_9GAMM ---QVTNDIQNIEKKYGGKIGVYIINRNDWSNF-AVNASFYFPICSIYKFLVLGAILKQSM -ADNKLLNQKVKISKNQIVGYSPITRKHINQTMTVKQLCKASMQ-GYNTATNILIEKLGGL -KNLNKFILSLADHVTKIVNLEPKVNHVSLITNENKTTPKIMARDINKLAFSDALDKKHCL -MFKKWLIASSTGNNSIGAEIPDEWEVGDKTGTCQYGTTNDIAIIWPDDNRAVIMAIFYTK -SQKNAKPNSKILREVTKILLD-- ->[subseq from] uncharacterized protein LOC111067177 n=1 Tax=Drosophila obscura TaxID=7282 RepID=UPI000BA0DE7F -------------------------------------------MCSTFKASLAACVLSRID -QGHDTLEITLSFSATDIKDYAPVAKANLARGLTLRDLCAGAVEQSDNVCANLLLTHIGGP -SALTAFWRALGDTTTRLDAYEPELNRTPLGRLENTTTPTAMTSVLRAITLGPALSAPSRA -LLVQWMIACQTGTHRLRAGLPKHWVVGDKTGNNGKDAAGDIAIIWPKSDTPLLVSAYTRG -GKPTETDFATAFAAIGSLVA--- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=A0A2T5YBK1_9SPHI ----LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID -KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP -QVVESYFAKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD -FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPSGEYFVISVFVTH -SKENQETNERIISDIAKAAWDFf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001411C655 ----LRKKIQQIASKTDGTLGVGILGLENRDTL-TLNNHVHFAMQSVYKFHLGLAILNQVD -KGNLKLNQKILIQKKDLLPWSPLREKYPNGNIPLSELFQFTVAQSDNNGCDILFRIMGGP -RVVDNYIKSIGMTDVSIRTTEEEMHKTEGAQFTNWTTPWSAVQLLEKFYQKKILSPTSHA -FMWKVLTEANTGSGKIKGLLPEGTLVAHKSGLSGTAATNDIGIVTLPNGKHFIISIFYGN -TKLSDKESDKVIAEVTKAAWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. AU58 TaxID=1874112 RepID=UPI000D6E5452 ----LRKTIEQIVSDKNAVVGVSIIGNNGTDTL-SLNGDKRFPMQSVFKFHIALAVLAEVD -KGTLSLDQTVEIGKDELLPWSPLRDENPNGGFTIKRLIQYNVSHSDNTACDILIRLIGTP -KTVEEYIKKSGIEDIQITFNEEGLQAKWENIFQNWTTPNAASETLKLFFENNLLSKSSYD -FFWETNIDTKTGKNRIRGQLPKEIIVANKTGWSGTAAVNDIGIVFLPNGNYFVVSVFVTD -SQEDFKTNAKIIADIAKATYDFy ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. TND4EK4 TaxID=1907408 RepID=A0A1N6U757_9BRAD ---ALDKGVAKIERRAKGRLGVALIDLKDHKLW-SYRGAETFPMQSVFKLPLAVAVLQQVE -AGKLRLDQPVSVTRKDLSLHSPLARQFKGESYPVQELIRLAAGMSDNTAADRLMREIGGP -QVVTAMLRAGGVQGLSVDRYERQFQPEALKDKRDASTPEASARFLEGFAEGNWLRPAHTA -FLTKIITETPIGADRIKAGLPAGSTLAHRTGAGLNHATNDIGIAALPDGRRFVIAIYLAG -SRVDANEREAALAEVAKLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A2E8M085_9ACTN -----SATFRILERALGGRLGVAFHAPARHAHI-AYRGDERFPMCSTFKTSLAAQVLSLGE -DGTLDLSERVTWTADDLIFHTPFTGRRVAQGATLSELAHAAQTVSDNLAANLLLDRVGGP -AGLTAFWRRLGDETSRLDRMETAVNFVPEGDVRDTTTPVAMARTLAKMLATNPLAAPRRR -ELRQWMIESTTGLKRVRAGLPEDWVAGDKTGNSGY-LRGNIGFALDPSEAPTFFAVYHQS -PVIDGQRVDAAFAQVGRLLA--- ->[subseq from] Uncharacterized protein n=1 Tax=Prosthecomicrobium hirschii TaxID=665126 RepID=A0A0P6VMJ4_9RHIZ ------RKVGEVAADVGGRLGVGILDLKSGQDW-YLAGDERFPMQSVFKAPLGVAVLRQVD -RKKLGLDQTVTITRRDVAMWSPIAKDMAGDRVAVRELVRGAVSLSDNTAADVLMRLIGGP -AAVTAALMESDIAGLRVDRYERELQPYLSTDERDTATPKAAVAFLAKLDRGAMLSADMTA -VMIRAMAESPTGAQRLKAGLPAGARLAHKTGTGPNAATNDIGIVTLPGGAKFAIAVFLAG -SALPEAQREAVHARVMAILAE-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. GH3-10 TaxID=2691582 RepID=UPI0013653783 ----LERRIAQIADGSDGRIGVAAIDLVSGEEV-SVLGDQRFPMASTSKIAIAATFLEGVD -KGRWSLTSEFPLMLAVRSPSTRVAPVRAGQHMPAHQLIDLMITRSSNSATDALLAAVGGP -SAVNDWARRAGLKDFSLDRDIATLVRTYHIDGRDSATPQAMVRLLAGIYQGEWLSPQSRE -VILDAMERCRTGRRRIPAMIPAGATVAHKTGTLNR-MAGDIGIVEMPDGRAIALAIFVTG -QSASRRRRDARIASIARALYDGf ->[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. TH134 TaxID=2067450 RepID=A0A2N4WT61_9SPHN ----LAAELRLIEAAGNGTLGAELYDTRSGMSV-GLNADRRFGHASSFKFSLAALLLQRHA -AGMIDADRRVMWTQADMIAHAPFTTERMASGASLRELARATQTTSDNPAANILLRELGGP -AALTAFWRSIGDDVSRLDRYEPEMNLVPPAEFRDTATPAAMARTVAKIVYGDVLPDAERA -ELKGWMVATETGLKRVRAGLPQGWAAGDKTGSSGY-NYVDIGFAEGPKGPPITFACYFRA -RQAEQARAELALSRIGRII---- ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter japonicus TaxID=376620 RepID=UPI0007C74462 ------ARLRAIEQSAGGRLGAFVLDTGSGRSF-GWRMDERFCHCSTFKLSLAATVLREND -AGRLDLSETLAVSRADIVAYSPVVEENLAKGLSFLTLAQAVQITSDNAAANVLLRRFGGP -EAVTRFWREIGDSTSRLDGYEPSINVIPPGTDKNSTTPRIMAETVRKIVLGNVLGTANRE -RLQGWMASTKSGLNRIRGGIPSSWGGFDKTGTGMGNKTNDLAVLIPPHGSPLIVTGYFEN -PADVRPADEAVLKALGEVAV--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina TaxID=290174 RepID=UPI000941F285 --eTLKQKIEDIINSKNAVVGVAINGMETKDSL-SINGQRHFPMQSVFKFPIALTILSEID -KGNLSLEQKIDIKKSELLPWSPIRKKYPEGALTIAEIIKYTVALSDNAGCDVLLKLLGEP -QAVEHYFSKLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANKILATFYKNNLLSKEGHE -FVWSVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYFIISVFVTE -SVENFETNEKMVSDISKAAWDYf ->[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI000ACB6059 ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYIGKTMSLKTLIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNESNLS -LLKQTMIENKKGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Serine hydrolase n=2 Tax=Halioglobus TaxID=1217416 RepID=A0A3L7DVI9_9GAMM ---KVAAALEAVTAGLVGVVGVAAQDMAGGTQV-FLNGDQPFPMASTYKIPIAVALLSKVD -AGELSLTDMIEIDDGEWVYSQVIAANFIYQGLSVANLLEVMITHSDNTATDVCLRLAGGP -AAVNRRLAQLGIEGMRVDRSTGDLLRRFEADPLDKSTPSAMLNLLISLYNGSALSEKSTE -FLLGTMARTVTMPDRLGGLLPRNTPVAHKTGTVG-GVANDAGYITLPDGRRFAIVVFTRG -SDTPPADRERAVAEVARTLYDYf ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GXS4_9BACT ---DLKKKISQIVAGKKVKVGVAILGPTPADTL-SFYGNGRFPMQSVFKLHIGLAMLSEVD -KGKFKLNQPIKVEKADLIPYSPLRDAHPNGGIELSKIIEYTVAESDNVGCELLLKLLGGP -QAVEQYLLSRGFKNVSIKINEQVMQKNWELQYQNWTTPKAANDLLAAYYFRKLLSSKSHD -FLWSVMKGTKTGKNRLRSQLPAETVLAHKTGSSGTAAVNDIGVLFLPSGSPVFISIFVTN -STESEATNEKIIADIGKVTWDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. HT-58-2 TaxID=2023229 RepID=A0A2L0GI50_9SPHN ----LAAELRIIEAAGGGTLGVEIYDTVSGMAV-GINRDRRFGHASSFKFSLAALLLQRHA -AGLIDADRRVTWSEADLLAHAPFTRERLATGATLRELARATQVTSDNPAANILLRNLGGP -AGLTAFWRSIGDEVSRVDRYEPEMNNVPTAEFRDTTTPAAMARTVAKIVYGDVLPEAERA -ELKRWMVETQTGLKRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPLTFACYFRA -RQSED------------------ ->[subseq from] Uncharacterized protein n=2 Tax=Stenotrophomonas sp. Leaf70 TaxID=1736233 RepID=A0A0Q4QH23_9GAMM ----LQRELDRLIAPFDGKVGAYVLDLRSGRSA-QVNGGSGFPMASTVKVPVAVHILALVD -EGRLDLRQQVLLQAADIYPMGGPMDIHLSAGITVRDLLHMMLTVSDNNATDILIRLGGGP -AAVDARMRALGIGGIRVDRYIWEMLALYNQDPRDTSTPAGMAELLRRIWEGRALRPDTTA -VLKAILLDCRTGQGRLKGMLPEATPVAHKTGTVDE-VINDVGVITLPGGGEMVVAVYLVS -GAGD-QARDRMIAQVARAAHDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDE0539 --dRLHSELAALASVHPGRVGICVQD-EDLAPI-CVNGEQRFSLQSVMKVVVAAAVMQAVD -ERRISLADRVTIRREDLSVIQPIADIVAERGTNIGDLVRRAVVESDSAATDVLISQLGGV -KAVQAFLNEAGLPDIRIDRTERELQTAYLQDPRDTATPRDMVGFLHMLAAGQLLSASSTA -YLLDVMSETITFPDRLRAGLPSDWTIGHKTGTSQNGVTNDVGILTAPDGRHVAIAAFVAE -STANKDDRAATIAAAARAVTAAy ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. BK498 TaxID=2512178 RepID=A0A4V3BXJ3_9BRAD ---SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVD -AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP -QVVTKMLRDGGIENMSVDRYERQFQPAALKDKRDAATPEASARFLEGFAEGNWLRPAHTA -FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAPKREAALAEAARLAVS-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. G0186 TaxID=2487064 RepID=A0A3G6P9V7_9FLAO ----LEQKITSITKGKKATVGVSVLGFEDSFTY-SKNGDKRLALMSVFKFHIACAALDLVD -KGKLSLDQKIFIKKSELYEWSPFREKYPHGNATLGEIIDYTVALSDNNLCDILIELVGGT -QAVQQFMNSKGVTDFQIKNSEHDMAKDWKSLYENYSTTNSSVQVLKKFYDGKLLSKKSTD -YLIQIMLGTKTGTNKMIEQLPQGTPVAHKTGSSGTVAENDMGIITLPNGKHYALAVFVSN -SKESEAVNCRIISDISKTVWNHf ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter oxydans TaxID=442 RepID=UPI00062C2A5F --------IASAEPREQEQSGWWALDLETNRTL-GENPDMHLPMCSTFKWLLAAATLSRTD -YGREHLGREIAFSRKDLIAASPAVKDALAASLSVGELCAATVSLSDSTAANLLLKRLGGP -AALTHWLRDHHDPVTRLDRYETALNRVPMGDLRDTTTPRAMVANLQNTLYGNNLSSASQA -QLLKWLLATTTGPKRMPAGLREGWRIGHKTGTWTRAASGDVAILLPPSGKPVLVAAYAAG -YSIPQSEKEGWFADIAHRAT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A3N2F7Q6_9FLAO --sTLEQKINSITKGKQATVGVSVLGFDNNFKY-SQNGEKRLAMMSVFKFHIACAALDLVD -QGKLSLDQKIFIKKSDLYEWSPYRVKHPEGNATLNEIIDYTVALSDNNLCDLLIGLTGGT -QAVQKFMNSKGIKDFQIKYSEHGMANGWDSLYENYTTTSSTVDLLKKFYDGKLLSKKSTD -YLMQIMLGTKTGANKIVEQLPKGTPAAHKTGASGRKAENDMGIITLPSGKHYAIAVFVSN -SKESETENCKIISDISKVVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-9 TaxID=2610888 RepID=UPI00123D1E67 ---QTNDSFKSLEKQYNGKLGVYSINTPNKTSF-SYNENYHFPICSVFKFLLVGAILEKDM -HNKGFLEKKTLISEQDVKGYTPVTGKNINKSLTISELCFAAI-LSDNAAANILVEQIGGI -KEVTKFAKKLGDHDTIIKDDEPKVNYTSPDSNINKTTPKAITSDLYKLVSGDILDKKHKE -IFIQYLQKNYTGKNRIAVGMPKNWIIGDKTGTCGYGATNDIAIIWPQNSEPFALGMMYTD -PTKKASSNEKIIQQAAKIV---- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. CA7 TaxID=2604424 RepID=UPI001295C31D --eNLRKEINRIITAKNVTAGISIKNIENEDTL-SINGHMSMPMMSVFKFHIALAVLDQVD -KGKLKLYQKFLIKKEELLPWSPIRDEFPDGNLTLNQLLRYMVAHSDNNGCDILLRMIGGP -EFVQKFINKQGIKDITIKLDEEQMGKAWENLYVNVTTPEATTLLLEKFYNGKILKENTTD -YLYRIMVQTSRGLTWMKAGLPPGTELAHRTGISGRAAMNDVGIFKLPNGQHIILSVYLKN -IKEERADTEKIIADIANATYNYy ->[subseq from] Class A beta-lactamase n=1 Tax=Gluconobacter cerinus TaxID=38307 RepID=A0A1B6VM78_9PROT -------QIASAEPREQEQSGWWALDLETNRTL-GENPDTHLPMCSTFKWLLAAATLSRTD -YGRDHLGREIAFSRKDLISASPAVKDALAASLSVGELCAATVSLSDSTAANLLLKRLGGP -AALTHWLRDHHDPVTRLDRYETALNRVPIGDLRDTTTPRAMVANLQNTLYGNNLSSASQA -QLLKWLLATTTGPKRMPAGLREGWRIGHKTGTWTRAASGDVAILLPPSGKPVLVAAYAAG -YSIPQSEKEGWFADIAHRAT--- ->[subseq from] class A beta-lactamase n=1 Tax=Stenotrophomonas nitritireducens TaxID=83617 RepID=UPI000AA8A980 ----LQRELDRLIAPFDGKVGAYVLDLRSGRSA-QVNGGSGFPMASTVKVPVAVHILALVD -EGRLDLRQQVLLQAADIYPMGGPMDIHLSAGITVRDLLHMMLTVSDNNATDILIRLGGGP -AAVDARMRALGIGGIRVDRYIWEMLALYNQDPRDTSTPAGMAELLRRIWEGRALRPDTTA -VLKAILLDCRTGQGRLKGMLPEATPVAHKTGTVDE-VINDVGVITLPGGGEMVVAVYLVS -GAGD-QTRDRMIAQVARAAHDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. enrichment culture clone MS32-6A TaxID=979975 RepID=F1CKJ5_9GAMM -----------------------------------------FAMCSTSKFMAASAILKQSE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGE-------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Aureicoccus marinus TaxID=754435 RepID=UPI000CF41E2F ---RLLDQIAAVDKNLDGQLGFSVLHLESGQEI-SHFGNKRFPMQSVYKFPIALVMLQAVD -RGEFSLDQMVEISPSEYIPHSPLRDRFPRGTMSIKELLRYNISESDGTACDVLLRLLGGT -KETEKKLHALGITDMAIATTEMVQMKNDTIQYQNWATPRGMNQLLKVFHQGEVLSEPSGN -LLKEFMSISTWFDRRLKGKLPPGTKLIHKTGTSNNRATNDVGIIELPNGEHLAVSAFIMD -SRDQHQERENAIAQAARLAYNFw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1Z245_ECOLX ------------------------------------------------------------- --------QRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMEQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILV----- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Scytonema millei VB511283 TaxID=1245923 RepID=A0A1D2P6D4_9CYAN -----QERLKNLDSAAQGKVGIGVLDLNSGQSW-FLNGKQRFPMQSVYKLPSAIAVLKQVD -EGKISLKQLVTIMRRDLAPASPIIKELKGDRIPLRNVLEGSVGISDNTAADALVRLLGGT -KQVNAILGKLQIRNIRVDRLEQQMQPKYLTDPRDTATPEGMVNLLARLQSNQLLSENSTA -LLLKIMTDSPTGQKRLKAGLPENWSIAHKTGTGAGTATNDVGIASSPDGKRVAIAVFIAG -SKAPLEEREKVMSNIASRVVQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DDBE152 ---KLDEGIVAIEKEAEGRLGVALLDLKDRKSW-SHRGAETFPMQSVFKLPLAVAVLQQVE -AGTFRLDQPITVTRKDFSLHSPLAKAFKGERYPLSELIRLAAGESDNTAADLMMREIGGP -QVVTKMLRDGGVTGISIDRYERQFQPNALADPRDASTPEASAQFLEALARGSWLRPAHNA -FLMKVITETKVGGARIKAGLPAGSQLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRAEAAEREAALAAVARLAVS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A497E0S8_9BACT ---RLKAQLEEVIKTIQGEVGVAVKYLKTGEEL-NINGETSFPMASVFKVPILVEVMAQIK -EGRFSLDDEISLQPADLHLGSGLLNDLEAPGLSVRNLIYLMMLISDNSATDILLTKV-GP -DKVNQRLRSLGIDGITVNRTCQHLILQFARIPQDQSTPLAMARLLELIFTKQILDEPSCD -FIIKVMLRCQTGERRLRGDLPASVQVAHKTGTIG-GTVNDAGVIFLPNQGRVVIVVFTKG -TDEKTEDVERVIAQIARFVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A174LPE0_BACUN --sELENRIDSLLKGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase class A n=2 Tax=Parasphingorhabdus marina TaxID=394732 RepID=A0A1N6F9T3_9SPHN ---AARREIAAIEKQTGGRVGVALTSRSGETDF-SWRGGERFAMCSTFKAPLAFALFDAVE -KRDLDLDARFALKKSDLVPYAPYVEKRLAEDVSFMQLAKAAVAISDNAAANLILKAIGGP -AGFTRFVRNHGDEITRLDRIEPFLNENKPDDPRDTTSPEAFASLMHSLMIARP-KHKHST -TVYDWMANSPTGRNRIRLGLPYGWPVGTKTGTAAGGAVNDVAIFWPSGDEPRILSVYWDR -PTVSRVETELAMARIAKIA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. 1131 TaxID=1871628 RepID=A0A2S4M879_9BRAD ---RLDQEIAAIERQSQGRLGVALLDLKDRKSW-SHRGSETFPMQSVFKLPLAVAVLQAVE -AGSLKLDQQITITRKDFSLHSPLAKAFKGESYPLRELIALAAGESDNTAADTLMRLIGGP -QVVTKMLRDGGIGGISVDRYEREFQPLALKDPRDAATPEASTLFLEALAKGNWLRDPAHA -FLDTVITQTKTGPLRIRAGLPLGARFAHKTGAGLNHATNDIGIVTLPNGRVFAIAIYLAG -SKADEKGREAAHAAVAKAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Taibaiella koreensis TaxID=1268548 RepID=UPI000E59AE0F --eALRQSIQAIVDTARAHIGIGVLDLDTGDSL-LYNGADTFPMQSVFKFPLAVAMLHQIE -QEKKPLSTLVNLSRKTMDPWGPLLKEHKEEHITIGDLLDYSVKKSDNNACDALFRLAGGT -GTVNRYIRSLGITGMTIRATEAEMRTAWPVQYTNSCRPGAMLQLLQQFYRKKLLSPEHQQ -FLWQIMTDSENPSDRIKGLLPANAVVTHKTGTSDTNATNDVGIISLPNGKHIALVVFVSD -FKGGTARAAHLIALVAKAVWDHy ->[subseq from] Serine hydrolase n=1 Tax=Bosea sp. RCAM04685 TaxID=2283844 RepID=A0A370L0G5_9BRAD --aKLDSEIPKIEQQSGGRLGVALIDLKDRKTW-SHRGKEPFPFQSVFKLPLAVAVLQAVE -AGKFKLDQSITVTRKDLSLHSPLAKAFKGESYPLRDLLTRATGDSDNSAADLLLRLVGGP -QALTKVLRDGGVTGISVDRYERVFQPASLNDSRDSATPEASIAFLDGFAAGNWLREPEHT -RLIDIITETKSGPDRIRAGLPKGAGFAHKTGLGPNHATNDIGIVTLPNGRRFAIAVYLKG -ATADAKAREAAHAAIARLAVT-- ->[subseq from] Class A beta-lactamase n=1 Tax=Altererythrobacter sp. AY-3R TaxID=2268576 RepID=A0A4Q2KL53_9SPHN ----FKQQIARLADGSNGRIGVAVLDLATGQEF-SILGDQRFPMASTSKIAVAATFMEGVE -QGRWSLSSEFPLLIPARSEFSSVKAPVRKGKLPASQLIELMITRSSNPATDALLAAVGGP -EAVNDWMRRAGIEEFQLTRDIATLVRATAIDIRDSATPRAMTQLLAGLYQGRWLSKRSRE -VILGAMERCITGKRRIPALLPAGVTVAHKTGSLNN-TSSDIGIVRTPGGQAFAVAIYVTG -QG-TRPARENRIAQIARAVYSGy ->[subseq from] Uncharacterized protein n=2 Tax=Arsenicibacter rosenii TaxID=1750698 RepID=A0A1S2VNQ4_9BACT ---RLQAEINQVISRKKATVSVGIYDIGSRQSL-YINGDKYAPMQSVYKFHVALAVLKEVD -KGRFRLTQKMRIRKSDLVPYSPIGEAHPNGVLPLSEIIRYMVAESDGSACDYLFRLLGGT -KPVNDFIHQLGVWDVFIAATEEKMQANWDVQYTNRTTQKAMISLMKLFYEKKILSPASHT -FLWDVMLSTVTGPDRLKKGLPAGTPIAHKTGTSGMGAVNDAGFMTLPNGKHVAISVFVTN -STEGIEANERIIADIAKLTYAYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dyadobacter tibetensis TaxID=1211851 RepID=UPI00046EE21F --qQLRTEIKAILDESDGLVGVGVVDFETNESI-YFNAQERFPMQSVFKFPLALAVLQRVD -AGEWSLDMPIEVTPADLLPWSPIRERYPNGNLTLAEIIRYTVAQSDNNGCDILFRLLDGP -IEVNKAVAQMTSKGIAIVADEAGMAKGWDVQFGNYSTPVAMMDLFQKFWAGRILSPASTE -YLKKVLFETNTCEACMKGLLPKGAQVAHKTGRSATAATNDAGVLLLPNGKAVGLVIFVSN -SKASDSARERLIARISKAVWDQy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. Root672 TaxID=1736584 RepID=A0A0T2Q8I9_9SPHN --nALAQQIALIAEGSQGRIGVAAVDLTTGQEI-GVLGDERFPMASTSKIAIAATFLEGVD -RGRWSLDSQFPMMMPVASKSSRIAPVRAGESYSARALIDMMITRSNNQATDALLAAVGGP -SKVNDWARRAGIQNFNLTRDIATLVRAAHIDIRDSATPRDMVKLLSGIYQGQWLSASSRY -VIIDAMERCRTGTRRIPALMPADARVAHKTGSLNN-TSSDIGIITMPDGRAIALAIYVTG -QG-TRLNREARIANIARAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. Leaf258 TaxID=1736310 RepID=A0A0Q6JLI7_9NOCA ---DVSTGLQAVEERYDVTVGVSLLNTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP ---EDARDDLVRWTAADIERYSPVTTARLDTGLTAAELAEAAVRESDNTATNLVFDQIGGP -AELDAALSRLGDDVTDIVDVEPGLNTVGPDSTGNTTTADAFTTSLAALRGAGSSTDADAA -TLAEWMSGNATGDALVRAGAPSGWTVADKSGGAG-AVRNDIAVVTPPGRPPLVLTVLTRK -NDASAPYEDAAVSESAAVVLN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD53_ECOLX ---------------------------------------GRFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDH---------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. ZT4R6 TaxID=2593302 RepID=A0A552UXA1_9FLAO ---TLQKEIEDIIKNKKATVGVSIIGNNLKDTV-SINATNHLPLQSVYKFHIAIAVLSEVD -EGKFQLNQKIKLTHTDLLKWSPMRDDYPNGALSLAKILEYTLVQSDNNGCDILLRLLGGP -KFVDNYFIKNNFKNISIKATEEDMHKDWETQFKNWTTPKSATEVLIAYYNKKLLSQDSYN -FLWTTLKATTVGAKRIKGQLPKGTIVAHRTGTSGTNATNDIGVVFLPNGKYFFISVFVSN -SKEDNATNEKIIADIAKAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. Hurlbut01 TaxID=1681828 RepID=A0A0K9XW47_9FLAO ----LEQKLNSITKDKNATVAVSVHSFEDNIKL-SINGDKKLPLLSVFKFHIALTVLNLVD -QKKLSLKQKILVTKGDLHEWSPFRKKYPNGNITLEELLQYMVSQSDNNITDLLIRLVGGT -QSVQNFMDKMKVKDFTIKADESKMHEGYEFHYLNTSTANSLNQLLKNFYDKKIISKSSTL -FLMKTMLETTTGANKIVALLPKETPVAHRTGSSGKNAENDIGIITLPNGKHIALSVLVSD -SMESEETNTKMVAEIAKVVYENf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. HTF TaxID=2170732 RepID=A0A2U1R483_9FLAO ---DLRKELNQIIATKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNKVD -EGKLSLDQKIFIKKKDLHEWSPMRDDYPEGNLTLDKLLRYTVSHSDNNGCDVLIKLVGGT -KEIQKFITKQGIKDFVIKVNEQQMET-WKNLYINTSTPLATTELLEKFYKGEILKESSTK -YLYQIMTETSRGLTWMKAGLPEGTELAHRTGISGTNAMNDVGIVKLPNGKHFILSVYLKE -ITETKEDTEKIIADITKVTWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000983540E ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTG--------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter atlanticus TaxID=1267766 RepID=A0A0F7KWQ3_9SPHN ----FERQIAQLADGSNGRIGVAAIDLATGEQL-AVLGDQRFPMASTSKIAVAAAFLEGVD -QGRFSLTSEYPLLLPVNSQSSPVAPVRKGKYLQARELIHLMLTRSSNSATDALLAAVGGP -NVVNDWVNRAGITEYNLTRDIATLVRAVQIDTRDSATPKAMVQLLRGLYQGRWLSPESRD -FLIRTMEECRTGTRRIPANLPGDVTVAHKTGSLNN-TSSDVGILTAPDGRTIALAIYVTG -QG-SRLNREHKIASIARAIYDGy ->[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Root381 TaxID=1736524 RepID=A0A0Q9IJQ3_9BRAD --aKLDKEIVAIEREAKGRLGVALLDLKDRKTW-SHRGNESFPMQSVFKLPLAIAALQAVE -AGKLKLDDKITIRRSEFSLHSPLAKAFKGESYTLRELIRLTAAESDNTAADNLMRRIGGP -KVVSEMLRAGGIEGISIDRYEREFQPASFKDKRDKATPGASVLLLEAVAKGNWLREPSHS -ALIKHMLDNAGGRERIRAGLPEGSRYAHRTGAGLNHATNDIGIVTLPNGRVFAIAVYLAG -SKADAKAREAAHAAVARLAVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI000A3865C3 ----LAAELRIIEAAGNGTLGVELYNTATGQSV-GLNSDRRFGHASSFKFSLAALLLQRHA -AGLIDADRRVTWSEADMLEYAPFTRERIATGATLRELARATQITSDNPAANILLRELGGP -AGLTAFWRSIGDEVSRVDRYEPEMNLVPSTEFRDTTTPAAMARNVAKIIYGDVLPDAERA -ELKQWMVETETGLNRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYFRA -RQ--------------------- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X203_9BACT ---ALETELRRLAATLPGTVGIAVHHVGTGRLV-TVDADRAFPMGSVFKLPVAIAVLRRVQ -TGGLTLETPITIAPEAYYPYSPLRDAKNRAEVTVRDLVETMMVDSDNTAVDVLMARMGGA -DAVNAELRAAGVPDVSVHRTEGEVMAKFLADSRDTATPTALANLLARLDRGEVLDAERTK -ILVGMLDRNKTGGRRFRAGLPAGVRIGDKTGTNPVGTYNDAALVTLPSGARIALVVMTRE -AGDTGAAAEQLMASVARTVYAHf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7S2J0_9PLAN ---RLAARIKPLVSRHKGQVSVLVKHLGSGRSF-AWKSDRPMPTASLIKLAVMVEVYRQVE -KGRVDLDDRLKLDEDDKVPGSGLLRKYFTAGLTLRDAVRLMIAVSDNTATNLVLDHI-GL -ESTNRTMSRLGHLNTRIHAKVFRRETSIDPDRSGSTTASETVSLLEAIHRGKLVSESASQ -QMLEHLKACES-AERIPRFLPSGTVVAHKTGSVSQ-VRTDAGIIDSPAGG-IAICVLTSK -NAGPANAASRLIADISREAFLHf ->[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158B396 ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQNDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL -QNLNKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sunxiuqinia elliptica TaxID=655355 RepID=A0A4R6GUS0_9BACT ----LRDEINQILKDKSATVAVAIQGTEMHDTL-SINADRHMPMQSVFKFHLALAVLEQID -QGKLSLDHQLSFDKNRVDRYSPLREKYPQGAVSVAELLKYTVSLSDNLGCDLLFQLVGGP -EVVQSYLHQIGIKDIAIVYNELLMQSDWSHQYQNWTTAHATNQLLQLFFESQLLSTENHQ -FLLDILKGTTTGKKSIRGLLPKDAVVAHKTGHSGTGALNDIGIVFLPNGSYFYLSILVSD -SMEDNKTNQQLIAQISKLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Bosea sp. BIWAKO-01 TaxID=506668 RepID=A0A1E1V3C5_9BRAD ---KLDSGIQAIERDARGRLGVALIDLKDRKSW-SHRGQERFPMQSVFKLPLAVTVLQAVE -AGKLRLDQEILVKRNELALWSPMKKGFKGEEYTVTDLLTRSTGASDNSAADVLMKRIGGP -KVVTTMLNEGGLSGISVDRYEREFQPYINGEARDSATPEASIAFLEGLVRGNWLREPADR -LLTGILLKSPTGAQRIRAGLPTGATFAHKTGTGDNSAINDIGIVALPDGRRFAIAVYLAG -AQADATAREAAHAAVAKLAVE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A3S3JR79_9RHIZ --dRLHSELAALADAHPGRVGICVQD-ETSPPI-CVNGEQRFSLQSVMKVIVAAAVMKAAD -ERRIALEDRVTIRREDLSVIQPIADIVAERGTSVGDLVRRAVVESDSAATDVLISHLGGV -NAVQAFLDEAGLRGIRIDRTERELQTAYLKDPRDTATPRDMVGFLHRLATGQLLSASSTA -HLLEVMNGTVTFPDRLRAGAPSGWTIGHKTGTSQNGVTNDVGILTAPDGGRVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=UPI00068A408A ---TFAKDIDQIENEYNTKVGIYGINTENGKAY-QHNADERFAFASTYKAIASGILLNKVA ---PSELNKKVETNESEIVANSPVTEQYIGKTMSLKALIKASMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium hankyongense TaxID=1813876 RepID=A0A328AV99_9CAUL --kQLNGDIAAIAARLPAVLGAGLMNLESGEVW-SLNGERPFPMQSVFKAPLGAYALSEVD -AGLLSLDQVFTLDDIDLSPYSPIADAWPARRYTARELLVAAVGMSDNTAADILMRRVGGP -GALTAWLVGKKIEEVRVDRYERELQPRYLADPRDTATPRGMLTFLGMLAAGELISRASTA -LLLQIMTNTPTGAHRLKAGLPPGATLAHKTGTARTDAINDVGIVTLPDKRAYAAAVFLSG -STLDDAARDAAIADVARAMI--- ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. AS-1 TaxID=2015316 RepID=UPI0012FD8EF9 ---RLDKEIGGIEEQAKGRLGVALLDLKDRKLW-SHRGAETFPMQSVFKLPLAVAVLQQVE -AGKFKLDQPITVTRKDFSLHSPLVKAFKGERYPLSELIRLAAGESDNTAADLLMREIGGP -QVVTKMLRDGGIEGMSVDRYERQFQPKALVDKRDAATPEASARFLEALAQGNWLRPAHNA -FLMKVITETKIGADRIKAGLPAGSKLAHRTGAGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAPQREAALAEVAELAVS-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR561 TaxID=1500298 RepID=UPI0006469793 ----LDQKINSIIKDKKATVGVSVLGFENGFKY-SKNADKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKIALNKSNLLEWSPLRDKYPNGGVPLSEILEMTVARSDNNGCDIMLNLLGGT -QTVQKFMDSKGIKGFQIKYNEEAMHKDWNVQYENYSTMNSVTDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKLIEQLPKNTPAARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN -SMETDTFNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SSP7_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Class A beta-lactamase n=1 Tax=Pseudomonas sp. SST3 TaxID=2267882 RepID=A0A658G377_9PSED ---ALTQTVASIEARTGGHIGVSVTALESGQSW-SHRGDERFPIASTFKAFFMRPPTCFGC -RDEVELDTRVRFDETDLQSYSPITKDRVGGNMSLFELCSATTSMSDNTAANLILRNTGGP -QGFTTFMRSIGDAVTRLDRYEPELNDVGPGEKRDTTTPRAAARSLETLLLGDSLSTDSRE -QLKAWLINNKVGGPLLRASLPESWKIADRTGSGG-------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Oerskovia enterophila TaxID=43678 RepID=A0A161XB32_9CELL --hELDEALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA -YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP -TAVTSFAASLGARATRLDRIEPQLNEATPGDDRDTSTPDDVARIYGALLLERGAGALTAA -RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT -DSPGATWDDEAVAAITRLVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium taiwanense TaxID=363331 RepID=A0A0B4DA44_9FLAO ----LDQKINSIIKDKKATVGVSVLGFENGFKY-SKNADKKLPMQSVFKFHIVAAVLDFVD -KGKLSLDQKIALNKSNLLEWSPLRDKYPNGGVPLSEILEMTVARSDNNGCDIMLNLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNVQYENYSTMNSATDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKLIEQLPKNTPAARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN -SMETDAVNCKMISDISKTVWDYf ->[subseq from] Beta-lactamase n=2 Tax=Jannaschia seohaensis TaxID=475081 RepID=A0A2Y9B554_9RHOB ---SVGAAIERVATKLAGRIGFAAQEIGGDDVI-AFNGDETFVMASTYKVAIAAAVLDRVD -KGELSLDQMVDVTLDMMMIGDAALNTHPGLQLSIANVIEVMITESDNTATDISMGLAGGP -AAVTEYLRRIGISDIRVDRPTGEIIGDFEADPRDQATPLAMLELLLAIDSGAATSAESRD -FLIDVMSRTRTGAGRLKGLLPRGTPVGNKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0010236BAA ------------------------------------------------------------- --------------QNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRVVFIYTAG -SQAILVERNRTIAEV-------- ->[subseq from] Class A beta-lactamase n=1 Tax=Bosea sp. TaxID=1871050 RepID=A0A521LS37_9BRAD ---ALDKGVAKIERRAKGRLGVALIDLKDHKLW-SYRGAETFPMQSVFKLPLAVAVLQQVE -AGKLRLDQPVSVTRKDLSLHSPLARQFKGESYPVQELIRLAAGMSDNTAADRLMREIGGP -QVVTAMLRAGGVQGLSVDRYERQFQPEALKDKRDASTPEASARFLEGFAEGNWLRPAHTA -FLTKIITETPIGADRIKAGLPAGSTLAHRTGAGLNHATNDIGIAALPDGRRFVIAIYLAG -SRVDANEREAALAEVAKLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TH98_9BACT ----LRQKIQQIASKTDGTLGVGISGLENRDTL-TLNNHIHFAMQSVYKFHLGLAILNQVD -KGNLKLNQKILIQKKDLLPWSPLREKYPNGNIPLSELFQFTVAQSDNNGCDILFRIMGGP -RVVDNYIKSIGMTDVSIRTTEEEMHKTEGAQFTNWTTPWSAVQLLEKFYQKKILSPASHA -FMWKVLTEANTGSGKIKGLLPTGTIVAHKSGLSGTAATNDIGIVTLPNGKHFIISIFYGN -TKLSDKESDKVIAEVTKAAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000E69494F ----AAKSFDQIEQDNDTIVGVYGINTANGKVI-QHRSDERFAFASTYKAISSGILLQNTP ---TSELNKKITISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI -KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKMAATTLNHLLASENMSRPNLE -LLKHTMIHNETGDTLIKAGMSKDDVVGDKSGQGTYGSRNDLAFVYPKNQKPIILAIYTKK -TDKDAKPDDKVIQTAAETAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus saprophyticus TaxID=29385 RepID=UPI001247CD0B ---TFAKDIEQIENEYNTKVGIYGINTENGKAY-QHNADERFTFASTYKAIASGILLNKVA ---PSELNKKVEINESEIVANSPVTEQYLGKTMSLKALIKTSMLQSDNTANNKIMQELGGV -NGLKHELVQLGDDVSEPQRLEPELNYFDPNSKADTTTPRAAAQTLNSILTSNEMNGSNLS -LLKQTMIENKTGDTLIKAGMPNSYTVGDKSGQATYATRNDLAFIYPKGQKPIILAIYSKQ -DQKDAKPNDKVISDSAREVIKY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Hymenobacter sp. TaxID=1898978 RepID=A0A519YV03_9BACT -hpALRATIDRLATGDAGKVGVALQVLETNDTL-SYHNRQPYPMLSVFKLAIAMQVLHEVD -RGHLRLAQQLLLTKADLPGHSPLRDKYPGGNVSIQELLTYMVTVSDNNACDVLLRLVGGP -SKLTAYVRQLGVRPFVAEVSEAQMGAVWANQYRNWSYPSTQVDLLVQVYHRTALSQASSA -LLWQLLLDTSVGPQRIKGLLPAGTPVAHRTGTSGTNALNDAGVITLPNGQHVALTVFVAD -SPADTATRELLIATIARAVYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LYZ9_9BACT --------------------GVAAWRLDHGPRF-LLNADEAFPMASTFKVAVAGALLAKID -AGTLSLETVLPVDKSRYVESEVIADALIHSGLSIHNLLELMLTRSDNTATDVLTSAAGGP -TAVTAWVRAQGITGLRVDRDTAGIVRAFDKDPRDSSTPNAMAELLTKIFTGHALSPASTK -EIIGTMERCHTGNDRLRARLPATTTVADKTGTLG-GSVNDVGVITLPNGGQVVCAVFIKK -SDLPFADREKVIADIARAVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9173E --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. B11 TaxID=2060312 RepID=A0A2Z5YU75_9SPHN --sALERQIASLADGSRGRIGVAAIDLATGQQV-GVLGDQRFPMASTSKIAIAATFLEGVD -QGRLSLTSEYPLLLPLSSKSSAIAPVRKGQYLQARELIQLMLTRSSNSATDALLAAVGGP -SAVNDWARRAGVKEYNLTRDIATLVRAVQIDIRDSATPRAMVQLLTGLYQGRWLRPESRD -FLIGTMEQCRTGTRRIPAQMPGDVTVAHKTGSLNN-TSSDIGILTAPDGRSIAVAIYVTG -QG-SRLNREAKIAEIARALYDGy ->[subseq from] Beta-lactamase n=1 Tax=Hymenobacter sp. TaxID=1898978 RepID=A0A519T0U2_9BACT -hqALRAEVGQLAPAASARVGVSMRVLGTGDIM-SYHNRQHYSLLSVFKLAIAMAVLHQVD -QGKLRLTQPISLTKADLPKYSPLRDKYPEGNMPVQELLRYMLVVSDNDACDILLKLVGGP -RQVTAYLRGLGIRPVVIAFSEAQMGAVWSAQYANWSYPAAQVELLDRVYRRTALSAASSH -LLYTLLRATSVTPHRLKGLLPPGTPVAHRSGTSSPNATNDVGIIELPDGRHIALAVFVSD -SYAEVAAQELLIAKIAQAVYKEf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR480 TaxID=1500296 RepID=UPI000647776F ----LEQKINSILKNKKATVGISVLGFENSFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIALNKSNLLEWSPLRDQYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTQSAVDVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISKEVWEYf ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Chryseobacterium sp. ON_d1 TaxID=2583211 RepID=A0A4Y4MAJ1_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD -HGKLSLDQKIMLNQSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QVVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSASDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFISN -SMETDVVNCRMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369I2M6_9BACT --dALRSNIQQIVSSKNAVVGVSIIGNNGKDTM-SLHGDRHFPMQSVFKFHIALAVLSEVD -KGKLSLDQKIEIGKDELLPWSPLRDENPNGGFTIERLIQYSVSNSDNTACDVLIRLIGTP -KTVEEYFKKNNIQDIQITYNEEEMQSKWENMFENWTTPKAASETLKMFYENNLLSKSSYD -FFWKTNIETTTGEKRIKGQLPIGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVSE -SKENFDTNEKIIADIAKATYDFy ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6YQ12_9BACT ---RVEKELERISKLAKGKVGISAVHLESGKRI-SMNLYEKYPMASTVKIAIAVQLLSKIE -KGELSLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMTISDNSATDILLRLAGGQ -KAVMERLRILGIDGMSVDRTIIQLIAKLRTDPRDTSTPDAMVNLLTQIYNGKALKPESRD -LLLAVMERCKGGLARLKGYLPAETVVAHKTGSLNATATDDVGIITLPDGGHIAIAVFVAS -SAQPLAEREQTIAHLTRAVYDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium glaciei TaxID=1685010 RepID=A0A172XZ44_9FLAO ----LEKKINSIIKDKKATIAVSVLGFEDDFNF-NKNGEKKLPMQSVFKFHIAAAVLDLVD -KGKLSLDQKILLDKSNLLEWSPLRDKYKDKNVPLSEIIDQTVAMSDNNGCDILLNLIGGT -QTVQKFMNSKGVKGFQIKFNEEAMHKDWQAQYENYSTTNSAVQVLKKFYDGKLLSKKSTD -YLMKVMLGTKTGLNKMVEQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYVIALFVSN -STETDAINCKIISDISKTVWDHf ->[subseq from] Beta-lactamase n=1 Tax=Hyunsoonleella pacifica TaxID=1080224 RepID=A0A4Q9FUL1_9FLAO --eTLRKKIDSIINTKSAIVGVAINGIKTNDTL-SINGQRHYPMQSVFKFPIALTILSEVD -KGNLSLDQKIEIKKNELLPWSPIRKKYPEGALTIAEIIEYTVALSDNVGCDVLLKLLGKP -QVVENYFLSLGFKDFAVKINEETMQGNWDLQFLNWTTPKEANKILITFYENKLLSKESYD -FIWNIMKGTKTGKNRLRGLLPEEIIVAHKTGSSGTAAVNNIGIVFFPNGKHLTISVFVTD -SKEDFKTNEKIISDISKVAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. Root700 TaxID=1736591 RepID=A0A0Q8MFQ4_9CAUL -----------AERARPGVLGVGLMNLESGEVW-LFNGDLRFPMQSVFKAPLGAAVLAEVD -AGRLDLEQPITLTENDISPHSPIADAWPARSYTVRELLVAATGESDNTAADVLMKLIGGP -GAVTAWLDDDHVNEIRIDRYERELQPAYLADERDTATPRGVLTFFYTLDEEPILSPTSKA -LLMKIMTETPTGAQRLKAGFPAGSVFAHKTGAGRNSATNDIGVVTLPDGRRYAVASFLKG -ATLDEAGREAIHADVARAIT--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B1FEC8C ---DVSTGLQAVEERYDVTVGVSLLNTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP ---EDARDDLVRWTAADIERYSPVTTARLDTGLTAAELAEAAVRESDNTATNLVFDQIGGP -AELDAALSRLGDDVTDIVDVEPGLNTVGPDSTGNTTTADAFTTSLAALRGAGSSTDADAA -TLAEWMSGNATGDALVRAGAPSGWTVADKSGGAG-AVRNDIAVVTPPGRPPLVLTVLTRK -NDASAPYEDAAVSESAAVVLN-- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aestuarii TaxID=650004 RepID=UPI00132AA8AC ----LEQQIASLADGSNGRIGVAAVDLSTGQRI-SVLGDQPFPMASTSKIAIAATYLDMVD -QGKLSLSSEFPLMLAVRSTFSTAAAPVRQGQMPAIELIDLMITRSSNPATDALLAAVGGV -DAVNAWARRAQIEEFRLTRDIATLVRAVHIDLRDSSTPAAMVELLSGIYQGRWLTPASRS -VIIDAMERCRTGTRRIPALMPQDVTVAHKTGSLNN-TSSDIGILTAPDGRSIAVAIYVTG -QG-SRSNREARIASIARAIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. UNC402CLCol TaxID=1510531 RepID=UPI00068EB1FC ---SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE -AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP -QVVTKMLRDGGIENMSIDRYERQFQPAALKDKRDAATPEASARFLEGFAEGNWLRPAHTA -FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAPKREAALAEAARLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Flavobacterium seoulense TaxID=1492738 RepID=A0A066WVB1_9FLAO ---SLRHHIKKIAASTNAVVGVSIVGNNGVDTI-AVNAKRHFPMQSVFKFHIAVTMLSEID -KGNFSLDQKIKIQKKDLVPYSPIREKYPEGTLTIAEILKYMVSQSDNIGCDVLLRLLGGP -QFVENYFLNNKFKDISIKINEEVMQNNWDLQFQNWTTPMAANQVLASFYSQKLLSKKSHD -FIWKIMRETSTGLDQLKGKLPEGTVVAHKTGWSGTAAVNDVGVVFLPTGEHFFISIFITD -SKEDKTADAKIIAAIAKAAWDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. IPPAS B-1204 TaxID=2483793 RepID=A0A3M9YPC7_9SPHN ---RLAAELRIIEAAGNGTLGVEIFNTATGMAV-GLNSDRRFGHASSFKLSLAALLLQRHA -AGAIDADRRVTWTQADMLEHAPFTSERMATGATLRELARATQITSDNPAANILLRQLGGP -AALTAFWRSIGDDISRVDRYEPEMNNVPTAEFRDTTTPAAMARTVAKIVYGDVLPEAERA -ELKGWMVETETGLRRVRGGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGGPITFACYFRA -RQGMQPIGEETLARVGRVI---- ->[subseq from] class A beta-lactamase n=1 Tax=Oerskovia sp. Root22 TaxID=1736494 RepID=UPI000702200B --hELDEALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA -YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP -TAVTSFAASLGARATRLDRIEPQLNEATPGDVRDTSTPDDVARIYGALLLERGAGALTAA -RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT -DSPGATWDDEAVAAITRLVVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. 9 TaxID=2035198 RepID=A0A2G6TEH8_9FLAO --nELRQQLNQIIASKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALAVLNLVD -EGKLSLTQEIFVKKRDLHEWSPMKEDYPDGNLTLDKILRYTVSHSDNNGCDILIDLVGGT -KVVQKFINKQGIKDFVIKVNEEQMKN-WKNLYINTTTPLAATQLLEKFYKGEILKEATTK -YLYQIMVETSRGLTWLKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN -ITESKEDTEKIIADIARATWNYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI0009A16929 ----LEQKINSILKNKKATVSVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNFVD -QGKLSLDQKVVLDKSNLLEWSPLRDQYPGGNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAIDVLKKFYDGKLLSKKSTD -YLMKVLWSTSTGMNKIVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. LM4 TaxID=1938609 RepID=A0A1T1BKG5_9FLAO --nELREKLDQIILGKNATVGISIKNIEDKDTL-SINGKLKAPLMSVFKFHIALAVLSQVD -HGKLSLDQKIFIKKKDLLPWSPIREDFPEGNLTLDKLLRYTVSHSDNNGCDILINLVGGT -KTVQKFINKQGIKDFVIKVNEEQMQS-WENLYVNTSTPLATTELLEKFYKGAVLKENTTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNALNDVGIVKLPNGKHFILSVYLKE -ITESKEDTEKIIADITKATWEYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella sp. enrichment culture clone MS32-6C TaxID=979976 RepID=F1CKJ6_9GAMM -----------------------------------------FAMCSTSKFMAASAILKQRE -TQTELLNRRVSLKKSDLVNYNPITEKHLDTGMTVGELAAAALQYSDNTAMNKLIEQLGGP -RKVTEYARTLGDKTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHVTLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGDKTGSGE-------------------------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. G0162 TaxID=2487063 RepID=A0A3G6S1W0_9FLAO --nDLRSKINTIISTKNATVGVSVKGIEDQDTL-SINPNQTMPMLSVFKFHIALAVLNQVD -KGKLKLDQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILLKIVGGA -PIVQKFVNQQGIKDFTIRLNEQQMNSF-ESYFVNTSTPLATTNLLEKFYKKKILKKETTK -YLYQIMVETSRGLTWMKAGLPAGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSVYLKN -INEEMKDTEKIIADIGNAVWEYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium chungangense TaxID=554283 RepID=UPI0004DF142F --nELREKLDQIILGKNATVGISIKNIEDKDTL-SINGKLKAPLMSVFKFHIALAVLSQVD -HGKLSLDQKIFIKKKDLLPWSPIREDFPEGNLTLNKLLRYTVSHSDNNGCDILINLVGGT -KTVQKFINKQGIKDFVIKVNEEQMQS-WENLYVNTSTPLATTELLEKFYNGAVLKENTTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISGTNALNDVGIVKLPNGKHFILSVYLKE -ITESKEDTEKIIADITKATWEYf ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. JAH TaxID=1742858 RepID=A0A101CBW0_9FLAO --sALEQKINSIIKDKKATVGISVLGIENDFKY-NKNSDKKLPMQSVFKFHIAAAVLDFVE -KRKLSLDQKIVLDKSNLLEWSPLRDKYPNGNIPLSEILELTVAKSDNNGCDIMLKLLGGP -KTVQKFMDSKGVKGFQIKYNEAEMHRNWNVQYENYSTTQSAVDVLKKFYEGKLLSRKSTD -NLMKVMLSTSTGLNKMVEQLPKSTPVARKTGASGTGAENEIAIVTLPNGKHYAIAVFVSN -SIESDAVNCKIVSDISKAVWDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea vestrisii TaxID=151416 RepID=A0A543NCX8_9BRAD ---SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE -AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP -QVVTKMLRDGGIENMSVDRYERQFQPAALKDKRDAATPEASARFLEGFAEGNWLRPAHTA -FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAPKREAALAEAARLAVS-- ->[subseq from] class A extended-spectrum beta-lactamase PER-15 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI00140F0D0F ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGAP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Beta-lactamase n=5 Tax=Gammaproteobacteria TaxID=1236 RepID=H6WJJ4_PSEAI ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHTDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVAQTAYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. 67-29 TaxID=1895723 RepID=A0A1Q3NQS0_9BRAD --dKLDKGIDAIETRSKGRLGIALMDLRDRKLW-SHRGSETFPMQSVFKLPLAVAVLQQVE -AGKFKLDQPITVTRKDFSLHSPLVKAFKGERYPLSELIRLAAGESDNTAADLLMREIGGP -QVVTRMLRDGGIQGMSIDRYERQFQPKALTDKRDAATPEASAEFLEALARGNWLRPAHNA -FLMKIITETKIGADRIKAGLPAGSSLAHRTGAGLNHATNDIGIASLPDGRRFVIVTYLAG -SRADAPQREAALAEVAKLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. StRB126 TaxID=878220 RepID=A0A077KJ89_9FLAO --sSLEQKINSITKGKQATVGVSVLGFENNFKY-NQNGDKKLAMMSVFKFHIACAALDLVD -KGKLSLDQKVFIKKSELYNWSPFKKNHPEGNIPLSEVIDYTVALSDNNLCDILIELLGGT -QAVQKFMDSKGVKDFQIKYSERGMANGWDSLYENYTTTHSTIQLLKQFYDGKLLSEKSTD -YLMKIMLGTKTGTNKIVEQLPKGTPAAHKTGSSSTIAENDMGIITLPNGKHYAIAVYVSN -SKESEAENCKIISNISKAVWDNf ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. ok626 TaxID=1761882 RepID=A0A1G9P4G3_9SPHI --sSLQQKIEGIINGKNADVGISVLFFGDRRSV-SVNGDKHYPMQSVYKFHLALAVLDQVD -KGKLSLQQNIFVKKSDLLPWSPLRDKYPNGNLPLSEIIKFTIAQSDNNGCDILFRLVGGP -NKVHKYIANLGIKDCAIVATEEEMHADDKVQFTNWTTPKAANALLLKFWNGTVLKKNTTA -FLKKTMEETVSGPNKIKGLLPAGTIVAHKTGYSGTVATNDIGVITLPNGNGMLISVFVSM -SKGNEKENDLIIAELARAAWD-- ->[subseq from] Beta-lactamase n=1 Tax=Tenacibaculum caenipelagi TaxID=1325435 RepID=A0A4R6TDT5_9FLAO ----LRKKIEKIVSDKNAVVGVSIIGNKGKDTL-SLNGDKRFPMQSVFKFHIALAVLSEVD -KGTLSLDQIVEIDKDELLPWSPLRDENPNGGFTIERLIQYNVSHSDNTACDVLIRLIGTP -KTIEEYIKKSGIEDIQITFNEEGLQARWENIFQNWTTPNAASETLKLFFENNLLSKSSYD -FFWETNKETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKHFIISVFVTD -SQENFKTNERIIADMAKATYDFy ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. ERMR1:04 TaxID=1705393 RepID=A0A0N1DYR6_9FLAO ----LDKKINSIIKDKKATVAVSILGFENAFNY-NKNGEKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKITLNKSNLLEWSPLRDKYKDTNVPLSEIIDQTVAMSDNNGCDILLQLIGGT -QTVQKFMDSKGVTGFQIKFNEEEMHKDWKVQYENYSTTNSAVQVLKKFYDGKLLSKKSTD -YLMKVMLGTQTGLNKMVEQLPKNTPVARKTGASGTGAENEIGILTLPNGKHYAIALFVSN -STETDAVNCKVISDISKTVWDHf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Francisella TaxID=2610885 RepID=UPI0011B3A3CF ---TLDDSFKNLEDKHHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QHKGFLDKQILITQDDIGTYAPVTGKNIGKTLTISQLNHAAI-LSDNPAANILVREIGGL -EKLNKLVTKLGDKDTIIKNDEPEINRTKPDNNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN -PSVKAPSNEKIIQQASKLVAD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. Aq78 TaxID=1191889 RepID=UPI000D104779 --eTLRKKIDSIINTKKAIVGVAINGIEVKDTL-SINGQRHFPMQSVFKFPIALTILSEID -KGNLSLNQKIDIKKSELLPWSPIRKKYPEGGFTIAEIIEYTVALSDNVGCDVLLKLLGEP -QAVENYFSSLGFREFAVKINEETMQNNWDSQFLNWTIPKEANKILATFYENKLLSKESYD -FIWNIMKGTKTGKNRLRGQLPKETVVAHKTGWSGTAAVNNIGIVFLPNGEYFTISVFVTE -SVEDFETNEKIISDISKAAWDYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium viscerum TaxID=1037377 RepID=A0A316WI39_9FLAO --kDLRNKINEIISTKKTTVGISLKGIEDKDTL-SINGNKETPMMSVFKFHIALAVLHQVD -KGKLKLDQKFFIKKEALLPWSPMRDEYPQGNLTLDQLLRFTVSHSDNNGCDILLNIIGGT -EVVQKFINQQGIKDFTIKLNEQEMSS-FDKCYINTTTPLATTELLEKFYKGKILKKETTK -YLYQVMVETSRGLTWMKAGLPIGTELAHRTGISGRAAMNDVGIIKLPNGKHVILSVYLKN -INEEMADTEKIIADISRVVWEYy ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. GH3-15 TaxID=2545755 RepID=UPI0010F59A66 ---AAKARIIDIEKRSGGRLGVALVDPAGRFIL-SQRGDERFAMCSTFKTLLAARILSDPN ---GLQLDDRLTINPAAVEGHAPFTRSRLDEGMTVGEAAEHIVTVSDNAAANLLLDQVGGP -SGLTQWIRTLGDDVTRLDRRELELNENAAGDPRDTTAPLAFAETYRKVMHDDALGAAQRD -HLAGWLNASVTGLDRLRAGVPEGWRVGDKTWYCAAVEINDIAVFDPDGSGWYTLAFMLDR -PRETGAFVDELAAEVGAIAAE-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. 18068 TaxID=2681414 RepID=UPI00135BDF1F ----LAQKVDSIIKDKKATVGVSVLGFEDGFKY-NKNAETKLPMLSVFKFHIAATVLDLVD -KGKLSLGQKILIKKGDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGA -QVVQKFMDSKGVKDFQIKHNEEQMHKGAKYLYENYTTTNSLSQLYKNFYNGKILSENSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAIVVFISN -STETDEVNCKMISDISKAVWDYf ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium sp. JUb78 TaxID=2485111 RepID=A0A4R3AKM6_9SPHI ----LRKNIQQIMQNKDAVVGVAINGINHSDTL-GVNADRRLPMQSVFKFPLAIVMLTEID -KGNFKLDQKIEITKRDLTPWSPIREKYPTGTLTIKEILEYTITLSDNVGCDVLLKLLGGP -QVVESYFVKKGFKDISIKINEKTMQSNWDKQFLNWSTPKEMNRILQTYYVNNLLSMPMYD -FLWTTMKSTNTGLKQLKGQLPDQTVVAHKTGSSGTAALNDVGVVLLPSGEYFVISVFVTH -SKENQETNERIISDIAKAAWDFf ->[subseq from] Beta-lactamase n=1 Tax=Aquimonas voraii TaxID=265719 RepID=A0A1G6W4F8_9GAMM -----SLRLAQLESAHGGRLGVAVLDTGSGLGF-GWRDGERFALCSTFKLPLAALVLREHA -DGRLDGHAPIALDSQPDVPHQPAVDAARASGLSALELARAIQTTSDNLAANLLLRLFDGP -QGFTARLRALGETDLRVDRWEPEMNEVPTGEQRDTVSPRGMARLCARLFGPGLLDASSQR -VLAHWMIETRTGLKRLRAGLPPDWRIGDKTGTAGANKHNDVAIAWPPRRPPTLIAAYYEA -DAHMRPQDDAVLAEVGRIVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI0011F3F563 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNAERDTTMPAAMATTLRNLVTRALLTLAA-- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=8 Tax=root TaxID=1 RepID=A0A127SH14_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter sp. SLTP TaxID=2683266 RepID=UPI0014124805 ---RLAAELRLIEAVGNGTLGVELFDTVSGMSV-GLNRDRRFGHASSFKLSLAALLLQRHA -AGAIDADKRVTWTEADMLEYAPFTRERIATGATLRELARATQVTSDNPAANILLRNLGGP -AGLTAFWRSIGDEVSRLDRYEPEMNIVPPAEFRDTATPAAMARNVAKIIYGDVLPDAERA -ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGEGNYIDIGFAEGPKGPPITFACYFRA -RQGDAARAELTLSRVGRII---- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A3N2F8T4_9FLAO --qDLRNKIKTIISTKNATVGISVKGIEDHDTL-SINGNKEMPMLSVFKFHIALAVLNQVD -KGKLKLDQKFFIKKEDLLPWSPIREEYKEGDLTLDQLLRYTVSHSDNNGCDILLKIIGGA -PVVQKFINQQGIKDFTVKLNEQQMNTF-ESYFINTSTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGLPIGTELAHRTGISGRAAMNDVGIAKLPNGKHFILSVYLKN -INEEMKDTEKIIADIGSAVWEYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium piscis TaxID=1114874 RepID=UPI00080B5277 --nELRQQLSQIISSKNATVGLSIKGIEDKDTL-SINGNLKVPMMSVFKFHIALTVLDKVD -QGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKVLRYTISHSDNNGCDILIDLLGGT -KEVQKFINKQGIKDFVIKVNEQQMRT-WENLYVNTTTPLATTVLLEKFFKGQILKESTTK -YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN -ITEKQEDTEKLIADITKVTWDYf ->[subseq from] Beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3IBF9_9BURK ---SVSAELQEIEKFAGGQLGVFARQTEPERSL-ALGADVRFLMCSTFKLLAAAGTLDRID -NHHELATRRLSYSASDLVEPHPVTGSNVQAGLPLWTLCEAAVAQSDSTAANLLMRAAGGP -AGLTGFIRSIGDGVTRIDRYELAANTA--SGDLDTTTPKAVVRSVHKLLLTDRLSLKSRQ -ALEEWMRADQRGLRRLRAGFPPSWMAGSKPGTSPV-VVNDVAVLRPPSGTPVIVGAFYRS -EPAPLEKREAVLASVGRVVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4V1CBM7_ECOLX --------------------------------------------CSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDATFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSG--------------------------- ------------------------ ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sunxiuqinia elliptica TaxID=655355 RepID=A0A1I2JJ26_9BACT ----LRDEINQILKDKSATVAVAIEGTAMHDTL-SINADRHMPMQSVFKFHLALAVLEQID -QGKFSLDHQLSFDKNKVDRYSPLREKYPQGAVSVAELLKYTVSLSDNLGCDLLFQLVGGP -EVVQSYLHQIGIKDIAIVYNELLMQSDWSHQYQNWTTAHATNQLLQLFFESQLLSTENHQ -FLLDILKGTTTGKKSIRGLLPKDAVVAHKTGHSGTGALNDIGIVFLPNGSYFYLSILVSD -SMEDNKTNQQLIAQISKLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Microscillaceae bacterium TaxID=2053581 RepID=A0A3C0I8L5_9BACT --eTLRSALQQIVADKNATVGVAIRSSNGSDTV-SLNGTQHFAMQSVFKFHIALAVLSQID -QGKFSLSQAIEVKPQELLPWSPLREANPQGGFPISVLLSYAVSVSDNVACDVLLRLLGGP -TVVETYFKQNNIQDISIQINEEIMQANWDLMFQNWTTPQAANEVLVKFYENSLLSAESYA -FVWKVMKETSTGLKRLKGQLPEGTVVAHKTGTSGTEAVNDIGVIFLPNGDYFFISVFVTH -SKEDEATNEKIVADIAKAAWDYf ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. KBW03 TaxID=2153362 RepID=A0A3N7AIL2_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKIVLNKSNLLEWSPLRDKYPEGSIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKGFQIKYNEEAMHKDWNIQYENYSTTKSAVDVLKKFYDRKLLSKKSTD -YLMKVMWSTSTGLNKVVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALTVFVSN -SMETDAANCRMISDISKEVWEYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium CCH10-E5 TaxID=1768797 RepID=UPI000837875E ---RLSREIVAIERDAKGRLGVALLDLKDRSLW-SHRGSERFPMQSVFKWPLAIAALQAVE -AGKLRLDQPVTIKRSEFSLHSPLAKAFKGEAYPVRELIALAAGESDNTAADILMREIGGP -QAVTAMLRAGGITGISVDRYERQFQPAALKDPRDSATPEASVAFVEAQAKGNWLREPAHS -ALIDITLETKSGPDRIRAGLPQGARFAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG -STADAKAREAAHAAVARLAVS-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium haifense TaxID=421525 RepID=A0A3G6SZ42_9FLAO --aELKKEISKITEGKKATVAVSVLGIDFPFQYnNENAEKKLPMQSVFKFHIALAVLDLVD -QGKLSLDQKVFIKKSELLPWSPIREKYTEGNLPLSEIIEYTVAMSDNIGCDVLLRLIGGP -TVVNDFIISKGVKDTQIIYNEELMQTAWRNQYENYTTTKSATKLLKDFYNGKVLSKKSTE -FLLGVMYRTSTGLNKIVEQLPKSAKVAHKTGSSGRNAENDIAIITLPNGKSYAIAVFLSD -STESYDVTCKLISDISEVVFENf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF25-17LB TaxID=2292922 RepID=A0A3A5YJU1_9BACE --sELENQIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium culicis TaxID=680127 RepID=A0A2S9CZK7_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFKY-DKNADKKLPMQSVFKFHIAAAVLNFVD -QGKLSLGQKVLLDKSNLLEWSPLRDQYPGGNIPLSEVIEYTVARSDNNGCDILLKLLGGT -QTVQKFMDSKGIKGFQIKYNEEAMHKDWNVQYENYSTTKSAVDALKKLYDGKLLSKKSTD -YLMKVMWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISREVWEYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis dnLKV2 TaxID=1235787 RepID=R9HTF7_BACUN --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGTLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. ov086 TaxID=1761785 RepID=A0A238ZCY2_9FLAO --nELRQQLNQIISSKNATVGVSIKGIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNKVD -EGKLSLTQEIFIKKKDLHEWSPMEKDYPEGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT -KEVQKFINKQGIKDFVIKVNEEQMKN-WKNLYVNTTTPLAATALLEKFYKGEILKESTTK -YLYQIMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN -ITETQEDTEKIIADITRTTWNYf ->[subseq from] Class A beta-lactamase n=1 Tax=Dyadobacter sp. AR-3-6 TaxID=2541721 RepID=A0A4R5DC11_9BACT ---RLQNELERIAKLAKGRVGVCARHLESGKQI-SLNLNEAYAMASTVKVAIAVQLFNKIE -KGEISLMTMVDLQPSDLHPGSGTLDVLFAKPLSVQNLLELMMVISDNSATDILLRLAGGP -KAVDQKIKDLGIQGMSVDRTIVELIAKLRKDPRDTATPLAMVNLLTGIYQNTVLKPESRD -NLLAVMERCRGGAARLKGYLPPSTLVAHKTGSLNATATDDVGIITLPDGGHIAIAIFVAD -SEQPIEQREQTIAHLTRSIYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B8LZP9_9PLAN ---RLAARIKPLVSRHKGQVSVLVKHLGSGRSF-AWKPDRPMPTASLIKLAVMVEVYRQVE -KGRVDLDDRLKLDEDDKVPGSGLLRKYFTAGLTLRDAVRLMIAVSDNTATNLVLDHI-GL -ESTNRTMSRLGHLNTRIHAKVFRRETSIDPDRSGSTTASETVSLLEAIHRGKLVSESASQ -QMLEHLKACES-TERIPRFLPSGTVVAHKTGSVSQ-VRTDAGIIDSPAGG-IAICVLTSK -NAGPANAASRLIADISREAFLHf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8MCU2_9BACT ---TLRTQIERVIPRARGQVGVAIKHVESGTEL-MVNADQTYPMASTYKVPILVELFYQRA -AGKLSLSDRIEVDPSDVHPGGTIALLLDGPGMSIHNLINLMMRVSDNSAADILLNRI-GP -ANVTARMRSLGLDKIRVDRSTLEMILRFNTTEKDVATPRQMTLLLERIYRGEIVDRASSD -EMMEFMNHSMIGQTRIPALLPEGTRVVHKTGTIS-GSTNDTGVVFLPGGGHLLMTVFTKD -AKAPAADREHVVAEIARFAYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium tiangeerense TaxID=459471 RepID=UPI00119D33E2 --nELREELNKIISTKNATIGVSIKSIEDKDTL-SINGKLNAPLMSVFKFHIALATLNLVD -KEKLTLTQKIFIKKQDLHKWSPIRDEFPEGNLTVDQLLKYTVSHSDNNGCDILLDLIGGT -EAVQKFINNQGIKDFTIKVNEQEMQTR-ENLYINTTTPLATTELLEKFYKGKILKKKSTN -YLHQIMVECSRGSTWMKAGLPDGTELAHRTGISGTNALNDVGIVKLPNGKHLIISVYLKN -ITETKENTEKIIADITKATWHHy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D4E6507 ------------------------------------------------------------- ------------------------TKKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RAU3_9BACT ------------------------------------------------------------- -------------------------------------------------------EQLGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7CE04 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPVADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Adhaeribacter aquaticus TaxID=299567 RepID=UPI00041376C5 ---SLPEKIQQIISAKNATVGVSIIGRNGKDTL-SINGERHFPMQSVFKFHIALAVLSQVD -KGTLSLDQKIKIKRKDLLPHSPLRDKYPNGALPLAEILSYTVSNSDNVGCDALLRLLGGP -QAVEKYFMENNFKAISIKINEEVMQHNWDLQFQNWTTPNAASNVLEAYYHNKLLSPKGYD -FVWKEMRENESGKNRLKGRLPEGTVVAHKTGSSGTAAVNDIGIVFLPNGEYYFISVFVSN -SKEDFNTNEKIIADISKAAWNY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Riemerella anatipestifer TaxID=34085 RepID=UPI00077B81C3 ----LDKKINSIIKDKKATVGISVLGFENNFQY-HKNGKKKLPMLSVFKFHIAATVLDWVD -KGKLSLEQKIFIKKEDLLKWSPIRDQYPDGNMSLDEIIRYTVAWSDNNGCDILLKLIGGT -ETIQKFINSKGIKNFQIKNNEEQMHKASKYVYENYTTTQSLALLYKQFFQGKIISEKSTH -YLYNIMLNTETGKNKLKEQLPPK-TVAHKTGSSGYEAENDSGIVTLPNGKHYSIVVFVNN -STEPEAVNCKMISDISKTVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium naphthalenivorans TaxID=273168 RepID=UPI000A051CBE ----LGQRLASVAEASQGRIGVAALDLATGREV-DVLGDQRFPMASTSKVAIAATFLEGVD -QGKWSLTSEFPMMIPVQSASTAVAPVRPGAYMSAGKLLELMLTRSNNYATDALLKVVGGP -DAVNAWVRRAGIEDWHIDRDIATLVRAKVVDKRDSATPLAMVKLLSGIYQGKWLSPSSRQ -TLLDTMSRCLTGKRRIRAGLPEDVQVLHKTGSLHN-TSSDIGIIEAPDGRVFAVAIYVTG -QG-SRPNREARIASIARTIYSGy ->[subseq from] class A beta-lactamase n=1 Tax=Type-F symbiont of Plautia stali TaxID=1560358 RepID=UPI0009E7A47E ------------------------------------------------------------- -----------------MVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QHATQFARTLGDTTFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLVLGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNYAPLVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] BlaGES-5 n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A2S1JL16_PSEAI ----FKTDLEKLEREKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVEWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMARTVAKVLYGGALTSTSTH -TIERWLIGNQTGDATLRAGFPKDWGCWRENWYLRQRGPERHWFFKAQER-DYAVAVYTTA -PKLSAVERDELVASVGQVITQ-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Tenacibaculum agarivorans TaxID=1908389 RepID=UPI00094BAEB9 --eSLREKIEKLINTKKATVGIAINGIEAKDTL-SVNGGKHFPMQSVFKFPIALTILSEID -KGNLSFDQKINIKKSELLPWSPIRKKYPEGCLTIAEIIEYTVALSDNVGCDVLLKLLGKP -QAVESYFSNLGFKDFAVKINEETMQNNWELQFLNWTTPKEANRILTTFYENKLLSKRSYD -FIWNVMKETQTGKNRLKGQLPKGTVVAHKTGWSGTAAVNNIGIVFLPNGKYFTISAFVTE -SKEDFKVNEKIISDIAKVAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Francisella sp. TX07-6608 TaxID=573568 RepID=A0A1S2WU14_9GAMM ----LNDSFKSLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPITQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNTPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUD9_9BACT --sELENRIDSLLNGKNATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. IHB B 17019 TaxID=1721091 RepID=UPI000720182A ----LEQKINSIIKDKKATVGVSVLGFENGFKY-NKNSEKKLLMQSVFKFHIATAVLDFVD -KGKLSLDQKILLNKSNLLEWSPLRDKYPNGNVPLSEILEYTVTKSDNNGCDIMLKLLGGT -KTVQKFMDSKGVKGFQIKYNEEAMHKDWNAQYENYSTMRSTVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGLNKLVEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAISVFVSN -SMESDAVNCKMISDISKTVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000489F1B0 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. RU37D TaxID=1907397 RepID=A0A1N6TD26_9FLAO ----LSQKINSIIKNKKATVGVSVLGFENGFKY-NKNGEKKLPMQSVFKFYIAATVLDLVD -KGKLSLDQKILLNQSNLLEWSPLRDKYPNGGVPLSEILEMTVAKSDNNGCDILLKLIGGT -QTVQSNMNSKGVTDFQIKYNEAEMHKDWKAQYENYSTTNSAVQVLKKFYDRKLLSKKSTD -YLMKIMLSTSTSLNKIVEQLPKNTLVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSD -SMESDAVNCKVISDISKTVWDYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=A0A2X2VLP6_9FLAO -----EQKINSITKGKQATVGVSVLGFENNFKY-SQNGDKKLAMMSVFKFHIACAALDLVD -KGKLSLDQKVFIKKSELYNWSPFKKKYPEGNIPLSEVIDYTVALSDNNLCDILIELVGGT -QAVQKFMNSKGIKDFQIKHSERGMASGWDSLYENYTTTHSTVQLLKQFYDGKLLSKKSTD -YLMKTMLGTKTGTNKIIEQLPKGTPAAHKTGSSGTIAENDMGIITLPNGKHYAIAVYVSN -SKESEAENCKIISNISKAVWDNf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus stepanovicii TaxID=643214 RepID=A0A411KFA0_9STAP --nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKTISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKKITLKKLIEATMLVSDNTANNKIIDELGGY -EQVKTRLIDLGDSTTHPSRKEPNLNYYSPKDKRDTSTPLAYGKTLKKLISDGNLSKANKD -FLLDLMFKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK -DR--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium 32-67-6 TaxID=1970502 RepID=A0A258CII2_9PROT --------------------------------W-AINGSDRFPMQSVFKAPLGAAVLAEVD -AGRLSLSDTITGSDEDLSPFSPVAAAYPGRRYRVDELLTLAVGASDNTAADLLMGRIGGP -GAVTAWLRSHGIEHMRVDRYERQLQPRYLTDPRDSTTPRDALLFLAMLARGELLSEASTR -HLLKIMEETPTGADRLAAGLPDGARLAHKTGTARTDATNDIGLITLADGRRYAVAVFLSG -STQSEAEREAIIADVARAVTQ-- ->[subseq from] Serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A2J0YYU1_RHIML ---RLRLELETLADAHPGRVGICVQD-QPKSPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD -EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGP -KAIQAFLEKAGLTGVRIDRTERELQTAYIKDPRDTATPRGMAAFLYSLASGSLLTAGSTE -FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE -SRAGQAERAAVIAAAARAITAAy ->[subseq from] Beta-lactamase class A n=1 Tax=Agromyces cerinus subsp. cerinus TaxID=232089 RepID=A0A1N6E7E9_9MICO -hrRLTEAIAELERATSVTIGVTALWHDSRRAF-RYRGDELFPMCSVFKTLAAGALVQARG -YDDVYWAKPIPFTLADVVGKDTRLN--RDTWATPEEMADAAIRYSDNTAGNLLLRELGGP -QAVTAFARSLGANRTRLDRPEPQVNEATPGDERDTSTPDDIAFLLQLLLIDQGAGALTTA -RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVIWRPGEEALTLAILTRT -DRADAPSNHDVLADVTRLIVA-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000F459A78 ----LEQKINSILKNKKATVGVSVLGFENGFTY-NKNANKKLPMQSVFKFHIAATVLNAID -QGKLSLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -RTVQKFIDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina megaterium TaxID=1443666 RepID=UPI0004724BEC ----LRKTIEQIVSDKNAVVGVSIIGNNGTDTL-SLNGDKRFPMQSVFKFHIALAVLAEVD -KGILSLDQTVVIGKDELLPWSPLRDENPNGGFTIKRLIQYNVSHSDNTACDILIRLIGTP -KTVEEYIKKSGIEDIQITFNEEGLQAKWENIFQNWTTPNAASETLKLFFENNLLSKSSYD -FFWETNIDTKTGKNRIRGQLPKEIIVANKTGWSGTAAVNDIGIVFLPNGNYFVVSVFVTD -SQEDFKTNAKIIADIAKATYDFy ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter lutipelagi TaxID=1964208 RepID=UPI0010F56315 ---RLNSRLRLIEASANGSLGASIYDPGTGTHV-SHNGFARFPHCSSFKLSLAALVLKSGH -DGVLDIDERIGWDKDALLGHSPFTTERLSEGATLMELAAATQIVSDNTAANLLLSRVGGP -EGLTAFWRAIGDEKSRLDRYEPDLNHVPIGELFDTTTPDAMSRTVSRLLREDVIDSGSRS -NLRGWMIDTRTGLDRVRAGLPEGWIAGDKTGTSLRSVYVDIGFVEPPVRGPLTYAVYFRA -NEKAQPAALAVFAEVGRVIT--- ->[subseq from] Class A extended-spectrum beta-lactamase VEB-24 n=1 Tax=Providencia rettgeri TaxID=587 RepID=A0A650A8F6_PRORE ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHYPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSETDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGTAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWDYy ->[subseq from] Uncharacterized protein n=1 Tax=Bosea vaviloviae TaxID=1526658 RepID=A0A1D7TVR3_9BRAD ---RLDQEVAAIERQSQGRLGVALLDLKDRKSW-SHRGSETFPMQSVFKLPLAVAVLQAVE -AGKLKLDQPITITRKDFSLHSPLAKAFKGESYPLRELIALAAGQSDNTAADNLMRLIGGP -QVVTKMLRDGGIGGISVDRYEREFQPLALKDPRDAATPEASTLFLEALAKGNWLRDPAHA -AFLDMVIETTSGPLRIRAGLPLGARFAHKTGAGLNHATNDIGIVTLPNGRVFAIAIYLAG -SKADEKTREAAHAAVAKAAVA-- ->[subseq from] Beta-lactamase n=4 Tax=Bacteria TaxID=2 RepID=A0A127SZJ8_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SH64_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea thiooxidans TaxID=53254 RepID=A0A0Q3I7K0_9BRAD -------DLRSLEERHGGRLGLFATR--ESQRV-GWRSTERFAFCSTFKLFLAAYVMQTVQ -QGRDRLDRAVPITAADMVPHGPVTQPAIGRTLTLEELCKAAVEVSDNPAANILIREMGGL -AAFQLWYRSIGDQVTSVDRMEIELNSALPGDMRDTTTAEQYVANLDRVVRGNLLSAAHLQ -LLVRWITETPTGAGRIKAGVPAGYTVGHKTGTGARSTHNNIGIMS--------------- ------------------------ ->[subseq from] Beta-lactamase class A n=2 Tax=Mucilaginibacter sp. YR332 TaxID=1855298 RepID=A0A497Z3S8_9SPHI ---KLRTQIVEIAKDAKGTVGVSILNLETRDTL-SLNGHAHLPMQSVMKFSIAITVLHEID -KGHFKLDQLIHIGKSDYYDYSPLKDKNPVADISIRELLSYMVSLSDNVACDVLIKTLGGI -NKVNDYIHSLGVKNIAFKATEFQMAQAWPVQYTNWAQVTDLTHLLDISFNPNFLSAASHA -YLWKIMQETSTGPNQIKGLLPAGTIVYHKTGRSGTAATNDIGIITLPNGKHLAIAIFVSD -TSVDLQMRESVIARIAKAAFD-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Runella zeae TaxID=94255 RepID=UPI000490391B --sDLRQKINKILATKNAVVGVAISGNNGKDTL-SINANRHYPLQSVFKLHIGLVVLSQVD -KGKLSLDQKIEIQKKDLLPYSPIRDKYPNGALSIAEILESTVASSDNVGCEVLLRLLGGP -KVVEDYFIQHNFKDISIKFNEEQQQGNWELQFQNWTTPKAANEVLAAFYYKKFLSAKSHD -FIWRVMRETTTGAKRLKGALPPNTVVAHKTGSSGTAAVNDIGIVFLPNGHHFFISVFVTD -SKENAETNEKIVADIAKVAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter sp. ZODW24 TaxID=2185142 RepID=UPI000DF7AF59 ----LEKQIAMLANGDNGRIGVAAVDLATGREI-AILGDQRFPMASTSKIAIAATFLEGVD -KGRWSLDDRYPLLHPIRSAYSSRAAPVKRGQYTARELIESMITRSSNSATDAMLAAVGGT -GKVNAWLRRSGIKEVRIDRDIATLVRATFIDERDSATPRAMVELLSGLYQGKWLSASSRR -VVIGAMERCRTGKRRIPKLLPANALVAHKTGSLNN-TSSDIGVITAPDGRSIAVAIYVTG -QG-TRSRREAKIASIASAIYEGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SW64_9BACT --sELENRIDSLLSGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium RBG_19FT_COMBO_58_17 TaxID=1797275 RepID=A0A1F5C174_9BACT ---RLRRRVEDVIKRAEGEVGVALRHLESGQSL-EINAGSRFPMASTFKLPVLVEIMAQVK -EGKLSLEDEVSVQKTEQHLGSGMLSSLTAPGLTVRNLANLMMMISDNSAADILLAKA-GP -ENVNKRLRQYGVEGISVNRSCQELIMKFILDPRDQSTPAAMNRLLEKVYKKEILDPESCD -LILSIMLQCQTGEGRIKGKLPPGAPVAHKTGTIA-GTVNDTGIITLPDGGHMAITVFTKG -FEDETEDVEKIIAEIARLVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=UPI000BA9323E ---ALADEVERLAAPAEGRVGVGIALLGSDEAV--VVGEGRHPMQSVFKLPLGMAVLAAVD -RGELSLDRRVAVTLADFVSHSPIRDRHPDGVLSVGELLGAAAGGSDGTAADVLLDLLGGP -AEVEGFLRGIGVEGVDVAVTEKDMGRDYDAQYRNGATPAGALALLRALHAGRGLSQESRT -LLLRVLTETTTGPNRLRGRLPEGTPVAHKTGTSRTAATNDVGLVTLPDGRRLAVAVFVSD -SPADDATRERVIADVARAAYDAw ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Candidatus Chryseobacterium massiliae TaxID=204089 RepID=A0A3D9AP70_9FLAO ----LEQKINSITKDKKAMVAVSIHSFEDNIKL-SINGNKKLPLLSVFKFHIALTVLNLVD -QKKLNLKQKILITKADLHEWSPFRNKYPNGNMTIEELLQYMISQSDNNITDVLIHLVGGT -QSVQKFMDDLTVKDFTIKADESKMHEGFEFHYWNTSTTNSLNQLLKRFYDKKIISKTSTS -FLMKTMIQTTTGSNKIVALLPKDTPVAHRTGSSGKNAENDIGIITLPNGRHIALSILVSD -SMESEETNTKMVAEIAKVVYENf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00050A362A ------------------------------------------------------------- -------------------------EKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Francisella persica ATCC VR-331 TaxID=1086726 RepID=A0A0K2JRB7_9GAMM ---QVTNDIQNIEKKYGGKIGVYTINRNDWSNF-TVNASFYFPICSTYKFLVVGAILKQSM -DDNKLLNQNLKISKNKIVGYSPITRKYINQTMTIKQLCKASMQ-GDSAATNILIEKLGGL -KNLNKFILSLADHATKITNLEPKVNSVSLITNKNKTTPKIIARDINKLAFSDALDKKHRL -MFKKWLIASSTGNNLITAEVPDEWEVGDKTGTCQYGTTNDVAIIWPNDNRAIIMAIFYTQ -SQKNAKPNSKIIREVTKILLD-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A519LIB3_9FLAO ----LDQKINSIVKDKKANVGISVLGFENNFKY-DKDADKKLPMQSVFKFHIAAAVLDFVE -KGKLSLDQKIILNQSNLLAWSPLRDKYPDGNVPLSEILEFTVAKSDNNGCDILLKLLGGT -QTVQKFMDSKGVKSFQIKNNEAEMHKNWNLQYDNYSTTQSAVDVLKKFYDGKLLSKKSTN -YLMKVMLSTSTGLNKLIEQLPKNTPVARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN -STESDATNCKMISDISKAVWDDf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUC6_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Acinetobacter baumannii TaxID=470 RepID=E5KCK4_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQVLRL----- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga barathri TaxID=1647451 RepID=A0A3N4M6P0_9BACT ---SLRKTIDSIVTQTDGKVGVAILHLGSRDTL-TLNDTAHFPMQSTFKFPIAMAVLKQVD -EGKLKLDQEVPIGKNWMATHSPLRDSLAKVKPTIATMLSYMVSLSDNVACDVLLELIGGE -PVANDFIHGLGVNNIAIVASEIKMGKAWDVQFTNWCQPSAYTQLLDILDKGTALSKASND -FLLKIMFETTTGPGRIRGLLPKELQVAHKTGTSGAAATNDVGIIVLPSGQKLAIAVFVSL -SHADEATREKVIAQITKAAYDH- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Flavobacterium TaxID=196869 RepID=UPI000D9B2697 --nELRQQLNQIISSKNATVGISIKGIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNKVD -EGKLSLTQEIFIKKKDLHEWSPMEKDYPEGNLTLDKLLRYTVSHSDNNGCDILIDLVGGT -KEVQKFINKQGIKDFVIKVNEEQMKN-WKNLYVNTTTPLAATALLEKFYKGEVLKESTTK -YLYQIMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN -ITETQEDTEKIIADITRTTWNYf ->[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. YH-07 TaxID=2182384 RepID=A0A345YCK8_9SPHN -----SATFRILERALGGRLGVAFHAPARHAHI-AYRGDERFPMCSTFKTSLAAQALSLGQ -DGTLDLSERVTWTADDLIFHTPFTGERVAQGATLSELAHAAQTVSDNLAANLLLDRVGGP -AGLTAFWRRLGDETSRLDRMETAVNFVPEGDVRDTTTPVAMARTLAKMLATNPLAAPRRR -ELRQWMIESTTGLKRVRAGLPEDWVAGDKTGNSGY-LRGNIGFALDPSEAPTFFAVYHQS -PVIDGQRVDAAFAQVGRLLA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=A0A411KFJ0_STAXY ---STNNDIEKLEKKYGANIGMYALNTQNSEAL-SFNENKRFAYASTLKAISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITIKKLIEATMLFSDNTANNKIIDELGGY -EHVKNRLTDLGDTTTHPSRKEPDLNFYSPKDKRDTTTPMAYGKTLNKLIVDGNLSKANKD -LLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVALVYPDGQKPIILVIFTNK -DK--------------------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T1C3_9BACT --sELENRIDSLLNGNKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD69_KLEOX ---------------------------------------RSFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQD----------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. AU474 TaxID=2108529 RepID=UPI000D69F057 --eTLRQKIDSILNTKKTIVGVAINGMKVNDTL-SINGQRHFPMQSVFKFPIALTILSEVD -NGNLSLDQKIDIKQSELLPWSPIRKKYPKGVLTIAEIIEYTVALSDNVGCDVLLKLLGKP -QAIENYFSSLGFKDFAVKINEETMQNNWDLQFLNWITPIEANKILATFYENKLLSQESYD -FIWNIMKGTKTGKNRLRGQLPEETIVAHKTGWSGTAAVNDIGIVFLPNGEHLTISVFVTE -SKEDFKTNEKIISDISKMTWDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Flavobacterium sp. B17 TaxID=95618 RepID=UPI000344BA4E ---ALGQKINSIIKDKNATVGISVLGFEDGFTY-KRNADKKLPMQSVFKFHIAATILDYVD -KVKLSLDQKVLLDKTNLLEWSPLRDKYPNGGIPLGEVLEYTVAKSDNNGCDILLKLLGGT -QTVQRFMDSKGIKGFQIKYNEAEMHKDWNIQYKNYSTAASATDVLKKFYDRKLISKNSTD -YLMKIMFSTSTGKNKLIAQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYAIAVFVSN -STETDVVNCKMISDISKSVWDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium balustinum TaxID=246 RepID=A0A3G6TQ56_9FLAO ----LAQKVDSIIKDKKATVGVSVLGFEDDFKY-NKNATTKLPMLSVFKFHIAATVLDLVD -KGKLSLGQKILIKKGDLLEWSPIREKYPNGNLPLSEIINYTVAWSDNNGCDILLRLIGGA -QVVQKFMDSKGVKDFQIKHNEEQMHKEAKYLYENYTTTNSLSQLYKKFYDGKILSEKSTK -FLYDIMLNTSTGGNKLKEQLPKQ-SIAHKTGSSGKDAENDSGIVTLPNGKHYAVVVFISN -STETDEVNCKMISDISKAVWDYf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter neustonensis TaxID=1112 RepID=A0A192D3X4_9SPHN ----LAAELRIIEAAGNGTLGVEIFNTATGGSV-GINQDKRFGLSSTFKLSLAALLLQRHA -AATIDADRRVTWSEADLVFHAPFTRDRIASGATLRELARAAQLTSDNPAANILLRNLGGP -AGMTAFWRSLGDDVSRLDRYETQLNDVPTPEFRDTTTPAAMARTVARIIYGDVLPETERA -ELKGWMVETDTGLKRVRAGLPEGWIAGDKTGTSGY-IYSDIGFAEGPKGGPLTFACYFRA -RQTELARGEQALARVGRII---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KI40_9BACT --------FQELDEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRN--------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RFP5_9BACT ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMATTLRKLLTSP-------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. CF614 TaxID=1884364 RepID=A0A1I2LLK1_9SPHN ----FEQQLAAVAEASRGRIGVAAVDLASGRMI-DVLGDQRFPMASTSKVAIAAAFLEGVD -QGKWSLTSEFPLMIPVGSAYSSAVAPRAGEYMTAERLIELMITRSNNYATDALLKVVGGP -SAVNAWVRRAGIENWHMDRDIATLVRAVVIDKRDSATPVAMVQLLAGVYQGKWLSPQSRA -VLLGAMSRCVTGKHRIAAGMPEGVSVSHKTGSLNN-TSSDIGIVQTPDGRVFAVAIYVTG -QG-SRPGREARIASIARTVYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=UPI0005A571A6 ---EISNRLHNLEKLYGGKIGVYTINRNNNSNF-SHNQSFYFPICSTYKFLVVGAILKQSM -TDNNLLDKEVKISANQIIGYSPVTKKHINQTMTVSELSKAAI-QSDNTATNLLIEKLGGL -NNLNNFILSLHDHATKVAGLEPVANQVSLTTNQNKTTPKIMAKDINKLAFNSILDKKHRL -LFKKWLLENDSGNNRIAAEIPDEWEIGNKTGTCAYGSTNDVAIIWPDDDKAIIMAIFYTQ -SQKDAKPNSKIIREVTKILLD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4Y1PU18_KLEPN ------------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASRAATLRKLLTSQRLSARSQR -QLLQWMV----------------------------------------------------- ------------------------ ->[subseq from] CblA family class A beta-lactamase n=1 Tax=Bacteroides rodentium TaxID=691816 RepID=UPI00046EF653 --sELEKRIDSLLKGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAMLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMVRLLRTTDEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium cutihirudinis TaxID=1265740 RepID=A0A3D9FVM5_9FLAO ---DLRKELNQIIATKNATVGISIKSIEDKDML-SINGNLKAPLMSVFKFHIALTVLSKVD -EGKLSLDQKIFIKKKDLNEWSPMRDDYPEGNLTLDKLLRYTVSHSDNNGCDLLIKLVGGT -KEVQKFINKQGIKDFVIKVNEKQMET-WKNLYVNTTTPLATTELLEKFYKGEILKETTIK -YLYQIMVETSRGLTWLKAGLPEGTELAHRTGISGTNAMNDVGIVKLPNGKHFIISVYLKE -ITETKEDTEKIIADIAKATWNYf ->[subseq from] Beta-lactamase n=1 Tax=Croceicoccus marinus TaxID=450378 RepID=A0A1Z1FDC8_9SPHN ---TFRRQLFAVAPQAQGRIGVAALDLTTGQTV-SIQGDEPFPMASTSKIAIAATFLAGVD -SGKYSLFDRYPLMVPVASESSKVAPVRAGQTMTAEMLIERMITRSDNQATDALLAVVGGP -QAVNAWARKAGLGRFRIDRDIATLVRSRHVDVRDSTPPEEMVELIAGIHQGKWLSPASRG -LLIGAMTRTVTGSSRIKAGLPRGVSFGHKTGTLNK-TASDVGFVTLPDGRVVVMAIYVTG -QSGP-AARNAKIAEITRTIYNGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD50_ECOLX ----------------------------------------SFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVQDH---------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000480A4C1 --eRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=2 Tax=Planctomycetes bacterium Pla144 TaxID=2528003 RepID=A0A5C6CJH7_9BACT ---DLASRIQPLIDSFEGEVGVMIKQLETGEEF-EYRSTESMPTASLIKFPLMIATYQAIE -DGKLDLDQRVTLRDEDKVPGSGILTAHFSDGLSLRDVIHLMIVYSDNTATNLVIDQV-GL -PSTAELMKSMGFAETVLNSKVYRRDTRSRKYGLGSTTAKDMVSLLEKLQAGQLVSEHASK -QMLAHLRACDD-TSKFPRLLPPGLTVAHKTGAVSD-TRTDAGIIESRDG-PIALCVLTTN -IESDDNAAELLCANIAKAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Oerskovia enterophila TaxID=43678 RepID=UPI0008276110 --hELDEALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA -YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP -TAVSSFAASLGARATRLDRIEPQLNEATPGDDRDTSTPDDIARIYGALLLERGAGALTAA -RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT -DSPGATWDDEAVAAITRLVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A3E5EGM2_BACUN --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKLPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Photobacterium damselae TaxID=38293 RepID=UPI0010FED638 --------------------------------------------------LACAKLLADSD -KDKSVLTHQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTTPVAIVETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTQHKPMVMSIYIQQ -SSASMDERNKAIAIIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A126G806_PSEAI ---NLTLKIENVLKAKNARIGVAIFNSNEKDTL-KINNDFHFPMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRET-TGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium acidiphilum TaxID=505248 RepID=UPI000688D287 --------LSALERRSGGQLGVMVRDCATGHGF-GWRQDERFAHCSTFKLSLAAMVLAQID -AGRARGDEVLAYSVLDVLPASPVTEALAGREMSILALAQAAVERSDNTAANLLLARFGGP -AALTAFWRAMGDEVSRLDHNEPMLNRVGLGEVHDTTTPAAMAATLGRVLTGRVLSGASRA -LLWGWMKNCSTGLGRLRAGLPAGWQAGDKTGTEY-GRINDLALVLAPGGAPLAVTAYYLP -GGELRPADEAVLAAVMRIATD-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. ML3W TaxID=1538644 RepID=A0A088EY86_9SPHI ---SLRTNLENIVQLKDALVGIAITGIDKQDTL-GINADRHLPMQSVFKVPIAIVMLSEID -KGNFELDQEIKITKKDMTPWSPIREKYPKGVLTIREILEYTLTLSDNIGCDVILKLLGGP -QVVERYFTNMGFSDISIKINEKTMQSDWESQFRNWATPREINKILQTFYVKNLLSLEQYD -FLWSTMISTNTGLNQLKGQLPKHTVVAHKTGSSGTAALNDVGVILLPNGEYFVISVFVTN -SKENQETNENIIADIAKQAWDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Sandaracinobacter sp. PAMC 28131 TaxID=1715348 RepID=A0A501XJS5_9SPHN ----LEAQFAYLAKQTDGTVGVAVQKVGSTEVM-TLNKGVTFPMASTFKVAVAARIFERID -KGELKLDQIIPVDPKILVGGLAVMTPHDGISLSVHNLLELMITISDNTSTDVLTAQAGGP -AAVTDWLTRHGIKGQRVDADTAHLIYPFNADPRDTSTPEAMVELLMQIQSGKVLSEASTK -ELLAIMGRTSTGDKRLKGLLPIGTPVAHKTGTLMS-IANDVGFITLPDGSQFAIAVFVKG -DTKGSETQERVIAEMARTAYDYy ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUG7_9BACT --sELENRIDSLLNGKEATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis sp. FD7 TaxID=1914525 RepID=A0A2Z5UI08_9SPHN ----LQDRIHALWRAFPGKTGIAVQRIDGEWTL-SHRGGELFPQQSVSKLWVALAVLDAVD -QGRLTLDQRVRIGPEDLTLYQPIASRVRAEGMSVRELIEIAITQSDNTANDSLLRTVGGP -DAVRRFIAKKDLGAIRFGPGERLLQAAYLANPPDGASPAAIANALTRLARGALLSPESTE -YLLGVMSRTKSGPRRLKAGLPPDWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TSAPVPARMELMQAVSRAVAEY- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9213A --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVCFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE16F04 ---SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE -AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP -QVVTKMLRDGGIEGMSIDRYERQFQPAALTDKRDAATPEASARFLEGFAEGNWLRPAHTA -FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAPKREAALAEAARLAVS-- ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000C79764D --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPPGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEERAAMIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. Root1464 TaxID=1736467 RepID=UPI0006FC9CE2 -hrRLSDAIAELERATSVTIGVTAIWHDSGRAF-RYRGADRFPMCSVFKTLAAGALVQARG -YDEAYWAGPIPFTSADVVGDSTKLDTT-TWAATPEQMADAALRFSDNTAGNLLLRELGGP -PAVTAFARSLGATRTRLDRPEPEVNEATPGDERDTSTPDDIAFLFQKLLIDQGAGALTTA -RLQEWMLRNTTSGKRILAGLTPPFELADKTGLGGYGVVNDAGVVWRPGEEALTLAILTRT -DRADAPSNHDVLADVTRLIVA-- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI00078786E1 ----LEQKINSILKNKKATVGVSVLGFENGFTY-NKNADKKLPMQSVFKFHIAATVLNAID -QGKLYLDQKIKLDQSNLLEWSPLRDQYAGKNVPLSEVIEYTVAKSDNNGCDILLRLLGGT -RTVQKFIDSKGVQGFQIKYNEEDMHKDWNVQYENYSTTKSAVDILKKFYDGKILSKKSTD -YLMKVLWSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIITLPNGKHYALAVFVSN -STETDAVNCRMISDISREVWEYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. UNC23MFCrub1.1 TaxID=1449068 RepID=UPI0009DE7F62 ---DVSTGLQAVEERYDVTVGVSLLNTGTGETI-SYRGAERFGFASTVKVFLAAEFLRRTP ---EDARDDLVRWTAADIERYSPVTTARLDTGLTAAELAEAAVRESDNTATNLVFDRIGGP -AELDAALSRLGDDVTDIADVEPGLNTVGPDSTGNTTTADAFTTSLAALRGAGSSTDADAA -TLAEWMSGNATGDALVRAGAPSGWTVADKSGGAG-AVRNDIAVVTPPGCPPLVLTVLTRK -NDASAPYEDAAVSESAAVVLN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroidetes bacterium 46-16 TaxID=1895925 RepID=A0A1Q3X0A6_9BACT -----IAKIDSVINSLHANIGIAVTGLDFSDSI-FINANKHYPMQSVYKFPLALFVLDKVD -KGQLSLEMNVHTARGLVDKWSPMVKDFPGGDMTLRDLLTYAISKSDNNACDILFRTVGGT -AVVQKYLDGIGIKGINIAATEAEMKKAFEVQYSNWAEPVAMAHLLKMFYDTRLLSKDNTN -LLMRLMTQSENPDDRIKGRLPPGTVVAHKTGTSGRAATNDIGIITLPGHRHIAVVIFVSD -YKAGLKQGEQAIAEIAKLVWDYy ->[subseq from] Uncharacterized protein n=2 Tax=Bosea sp. PAMC 26642 TaxID=1792307 RepID=A0A126NXW0_9BRAD --aKLDREIIAIERQSKGRLGVALLDLKDRKTW-SHRGAERFPMQSVFKLPLAVAVLQAVE -AGKLKLDQPVTIKRSEFSLHSPLADALEGESYPLRELIARAAGDSDNTAADFLLRLVGGP -QAVTAMLKAGGITGMSIDRYERMLQPAALSDPRDSATPDASVAFLEALAKGNWLRDPHAA -WLDRVISETMSGPERLRAGLPEKARLAHKTGLGPNHATNDIGLVTLPNGRVFAIAVYLAG -STADAKQREAAHAAVARLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Flavobacterium subsaxonicum WB 4.1-42 = DSM 21790 TaxID=1121898 RepID=A0A0A2MIS9_9FLAO --sQLQKDIDKIVKNKKATVGVSIIGNNVNDTV-NINPSKHFPLQSVFKFHIAIAVLSEVD -KGNLQLDQKIVVDKKDLLKWSPMRDQYPDGALSLAQILEYTLIQSDNNGCDILLRLLNGP -KFVEDYFIKNNFTDIAIKATEEDMHKDWETQFSNWTTPKSASDVLIAYYNNELLSKGSYD -FLWTTMKATQVGAKRIKGQLPSTTIVAHRTGTSGTAAVNDIGVILLPNGKHFYISVFVSN -SKEDEKTNEKIISDIAKAAYNYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE2CCDE ---KLDGGIRTIEREARGRLGVALIDLKDRKSW-SHRGQERFPMQSVFKLPLAIAVLQAVE -AGTLRLDQDIRVRRNELALWSPLKKGFKGDEYTVTDLLTRSTGASDNSAADVLMKRIGGP -KVVTTMLNEGGIAGISVDRYEREFQPYIKGEARDSATPEASIAFLEGLAKGNWLREPHDR -LLTDILLKSPTGAQRVRAGLPTGATFAHKTGTGDNSATNDIGIVALPDGRRFAIAVYLAG -AQADATAREAAHAAVAKLAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. NM69_E16B TaxID=2516960 RepID=A0A4S2AXS7_9BACE ---RLENQIDSLLKDKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQGISLDSIVSIKASQMLPYSPLRKKFPNQDITLRKLMQYSISQSDNNACDILIEYVGGI -KYINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTMVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDKDNADIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00020F3C40 --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Pantoea anthophila TaxID=470931 RepID=UPI0009FE2C7A ------------------------------------------------------------- -----------------MVNYNPVTMKHIGSAMSLAELSAAALQYSDNAAMNKLLAYLGGP -QYATQFARTLGDTMFRLDRNEPGLNTAIPGDPRDTTTPSAMAASLNKLILGSALKDDQKA -TLTAWMKGNTTGAASIKAGLPADWIVADKTGSGDYGTTNDIAVIWPKNHAPLVLTTYFTQ -HDKSAAARKDVLASAARVIAD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUM3_9BACT --sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001296ACBA --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHGLATGQLLSASSTA -HLLEVMNRTTTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8QUH2_9BACT ---HLAGEVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILTMVD -QGDLALTDMIEIEQEDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA -EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEESSS -LLIDIMYRCQTGEARLKGALPPGTQVAXKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE -SKPDNPAMEPVIANIARAIHDYf ->[subseq from] Beta-lactamase n=2 Tax=Flavobacteriaceae bacterium (strain 3519-10) TaxID=531844 RepID=C6X4P0_FLAB3 ----LKKQIQQIIKDKNATVAVSVHDFENNKTI-HINGNKKLPMLSVFKFHIALAVLNEVD -EGKLSLDQNIFIKKSDLAEWSPIRDRFPDGNIPLSLLLKYTVAESDNNGCDIVLRLIGGT -GTVQKFIDSKDVKDFTIKADEAQMHRGDEFLYWNVTSTNSANKLLKDFFDKKTVSKPSTD -FLMNTMLETTTGQNKLVAQLPRGLPVAHKTGSSGKNAENDIGIVTLPNGKHYAISVFVSD -SMESEATNTKMIADISKIVFDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD88C71 ---SLDKGIAKLERRTEGRLGVALIDLKDHKLW-SWRGAETFPMQSVFKLPLAVAVLQQVE -AGKFKLDQPITITRKDLSLNSPIARQFKGESYPVRDLIRLAAGQSDNTAADRLMREIGGP -QVVTKMLRDGGIEGMSVDRYERQFQPAALTDKRDAATPEASARFLEGFAEGNWLRPAHTA -FLTKVISESKIGTGRIKAGLPPGSVLAHRTGLGLNHATNDIGIATLPDGRRFVIVTYLAG -SRADAPKREAALAEAARLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUA0_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-WYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase n=2 Tax=Bacillus thuringiensis TaxID=1428 RepID=C3H3B0_BACTU -----NDSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSDKRFAYASTHKALAVGVLLQKKS ---IEDLNQRVLYTREDLVNYNPITEKYVDRGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPG------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Aquimarina algiphila TaxID=2047982 RepID=A0A554VNG5_9FLAO --eTLKQKIEDIINSKNAIVGVAINGMEIKDTL-NINGQRHFPMQSVFKFPIALTILSEID -KGNLSLDQKIDIKKSELLPWSPIRKKYSEGVLSIAEIIKYTVALSDNVGCDVLLRLLGEP -QTVENYFSSLGFKDFSVKINEETMQNNWDLQFLNWTTPKEANRILTTFYKNRLLTQESHD -FVWNVMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGKYYTISVFITE -STESFETNEKMISDISKATWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium polytrichastri TaxID=1302687 RepID=A0A1M6ZVA5_9FLAO ----LDKKINSIIKDKKATVAVSVLGFENAFNY-NKNGEKKLPMQSVFKFHIAAAVLDFVD -KGKLSLDQKISLNKSNLLEWSPLRDKYKDANVPLSEIIDQTVAMSDNNGCDILLQLIGGT -QTVQKFMDSKGVKGFQIKFNEEAMHKDWNVQYENYSTTNSAVQVLKKFYDGKLLSKKSTD -YLMKVMLGTQTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYAIALFVSN -STETDAVNCKVISDISKAVWDHf ->[subseq from] Beta-lactamase n=1 Tax=Ignavibacteriae bacterium TaxID=2026749 RepID=A0A2E0VZJ3_9BACT --nALQRQFEQLADTIKGNIGVSALNIETGESI-SFNGNEKFPMQSVYKFPIAMVMLNEID -NGNFSLKDTILINESEYIPHSPIRDKYPNGILTIKEILEYNISQSDGTACDVLLRLLGGT -DKVEKSIHALGVKDIAISTTEMVQVANDTIQYQNWATPNAMNRLLEIFQNGNYLTEQSKN -LLLGFMSSNKWFDRRIKRLLPKETKLAHKTGTSSTRATNDVGIITLPDGSHLAISIFISD -SYDSQKKREMTIAQAAKAAYDYw ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=A0A508WY16_9RHIZ --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEERAAMIAAAARAITAAy ->[subseq from] Uncharacterized protein n=1 Tax=Oerskovia sp. Root918 TaxID=1736607 RepID=A0A0Q9BXL7_9CELL ----LDDALRDLERSRSLTVGVSVRG-GGRADY-GYRAAERFPMCSLFKPIAVGALLADKA -YDDAYWSREIAFGPEDLVENSPVTSATTTWRMTPAQLADAALRFSDNTAGNLVLREIGGP -TAVTSFAASLGARATRLDRIEPQLNEATPGDVRDTSTPDDAARIYGALLLERGAGALTAA -RLGDWMLRSTTSGKRFRAGLDGTYELADKTGAGGYGVVNDAGVLWRPGVEPTTLVVMTRT -DSPGATWDDEAVAAITRLVVA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Chryseobacterium rhizoplanae TaxID=1609531 RepID=A0A521FKJ9_9FLAO ----LEQKINSILKNKKATVGVSVLGFENSFKY-DKNADKKLPMQSVFKFHIAAAVLNAVD -QGKLSLDQKVALNKSNLLEWSPLRDQYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTQSAVDVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVERLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMISDISKEVWVYf ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000360B786 --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEERAAMIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Rudaea sp. 3F27F6 TaxID=2502208 RepID=UPI0010F8D21D ---DLQGRLEALAERAPGVLGVAVLDLQSGRSW-RVNADRGFPMMSTFKAALGATVLDRVD -HGALSLDRKVTLTRADMRNGPEAIRKEFDAGFDVRRLLDAAVSESDNAAADALIRLLGSP -AAVTAFLRAHGVDGMRVDRDEAGLAHAYLADPRDTSTPDAAVVFLRKLWRGELLARESTA -LMLEMMTHSPTVPNRLKGGVPAGARLAHKSGTSDTAAHNDIGILSWPDGRTVIVAGFLTA -SPASADERDAIFATLTREVTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Sinorhizobium medicae (strain WSM419) TaxID=366394 RepID=A6U9H5_SINMW --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEERAAMIAAAARAITAAy ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium detergens TaxID=1145106 RepID=A0A420BFH0_9SPHI ---QLKKQLQEIIAQKNATVGISIKGIAAKDTL-SINGNLKMPMMSVFKFHIALAALHQVD -KGKLRLDQKFFIKKDELLEWSPMRDDYPNGNLTLDQLLRYTVSHSDNNGCDILLKLLGGP -EKVQDFISQQGIKDITIKVNEQQMRT-WDNLYLNTTTPIATTLLLEKFYQGKILKKETSS -YLYQIMVETSRGTTWMKAGLPQGTELAHRTGISNRAAMNDIGIVKLPNGHHFTLSIYLMN -ITEKREDSEKLIADITGATWKYf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PASSN1 TaxID=2015561 RepID=A0A257GDP7_9SPHN ---AIEQQVAAIVAQGRGRIGVAAVDLDGGGQI-MINGDMPFPMASTAKVAIAATYLAGVE -QGRLRLDQQFPMMVPVAESRGAVAAVRPGEVMTAQSLMELSITRSDNHATDGLIAAVGGI -NAVNTWLSRIGVSGQRLDHTMATLVRVTTIDTRTSSTPRAMAQLLAAIDRGGALSPESRA -VLLDTMTRTSTGRNRIRSGLPEGVVFAHKTGTLS-GVTDDVGIVRLPDGRHLAIAIFVTG -PEG-HTAHAGLIAQIARVLYDGy ->[subseq from] class A beta-lactamase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0013A56F02 ------------------------------------------------------------- ----------------------PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KEQTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE4FDA7 --dRLQARLQALAEAHPGRLGICAQDADSAPVC--INGDQRFSLQSVMKLVVGAAMMRAAD -RGRIRLDDPVTIRREDLSVIQPIADIVAARGTTIADLVRRAVVESDSAATDVLISRLGGI -AALRTFLAEAGIAEIRIDRTERELQTAYLYDKRDTATPRAMAKFLTMLASGRLLEPASTR -QFREIMAATVTFPDRIRAGTPEGWSVGHKTGTSQNGVTNDVGILTAPDGGFLVIAAFLAE -STAPAPGRAAVIAEAARAITASy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Cloacibacterium normanense TaxID=237258 RepID=A0A1E5UHB1_9FLAO --aELKKEISKITEGKKATVAVSVLGIDFPFQYnNNNAEKKLPMQSVFKYHIALAVLDLVD -QGKLSLDQKVFIKKSELLPWSPIREKNPEGNMPISELIEYSVAMSDNVGCDVLLRLIGGP -KVVHDFLIYKGAKDTQIVYNEEIMQSAWKNQYENYTTMKSATRLLKDFYKGKILSKKSTE -FLLGVMYRTSTGLNKIVEQLPKSAKVAHKTGSSGTGAENDIAIITLPNGKTYAIAIFVSD -SMETWEVNCKMISDISKVVFE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. C05 TaxID=1945855 RepID=A0A1V3NXT3_9GAMM ---RLQQKLDALAQRAPGTLGVAVLDLQSGTEA-GVNAGQAFPMMSVFKAPVAAAVLSRVD -AGKLSLQQQVSVSRADVLSGSPSIGAHFRGEFTVEQLLKAAVSESDNTAVDALVKVVGGP -QVVTAFLRAHGIDGMRVDMDEAGVARAFLDAPTNRSTPDAAVGFLRKLHDNELLTQASTQ -YLLGLMAAQTI-PNRLRAGVPQGVGLADKTGTSGTAAYNDIGILSGPDGHTVIVAAFLTD -SHASDAQRDALFADIARAAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Nitratireductor soli TaxID=1670619 RepID=UPI00065E998B ---RLQAQLQALTDKHPGRVGICVED-ASLKPI-CVNGDQRFSLQSVMKVVVGVAVMRAVD -DGRLKLDDPIVIQREDLSVIQPIADIVAEQGTTIGDLVARAVIESDSAATDVLILELGGA -KAVQSLLDGAGIKGIRIDRTERELQTAYLKDERDTTTPRGMTAFLSALATGELLSPASTR -NFLNVMARTKTFPDRLRAGTPKTWTVAHKTGTSQNGVTNDVGILTAPDGGKIAISVFVAE -STASNDLRAAVIANAARATVAAy ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A3D4P0G7_9BACT ---RLRRRVEDVIKRAEGEVGVALRHLESGQSL-EINAGSRFPMASTFKLPVLVEIMAQVK -EGKLSLEDEVSVQKTEQHLGSGMLSSLTAPGLTVRNLANLMMMISDNSAADILLAKA-GP -ENVNKRLRQYGVEGISVNRSCQELIMKFILDPRDQSTPAAMNRVLEKVYKKEILDPESCD -LILSIMLQCQTGEGRIKGKLPPGAPVAHKTGTIA-GTVNDTGIITLPDGGHMAITVFTKG -FEDETEDVEKIIAEIARLVYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560HCX2_9PROT ----LQARLDRLAHDFPGHAGIAVRDPATGAVA-GVRADQRFPEQSVFKLTVAIALLDLVD -KGATDLDHKVTLYPEDRSVWQPLAKNITPGGTTLGDLMVRMVADSDNIAADTVLRLIGGP -ATVQAALNARGLEGIRVDRDERHLQSAYLSDPRDTATPAGMALLLERLNKGDLLSPASTR -RLLDILDHTTTQPHRLKAGLGAGWAVAHKPGAGPTLANNDVGLMTAPDGGRYAVAVYVAS -VHGPREGADAFIAAVARAVVESw ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. JRR 20_7 TaxID=2183917 RepID=A0A495NQU2_9FLAO --nELRQQLSQIISSKNAAVGLSIKGIEDKDTL-SINGNLKAPMMSVFKFHIALTVLDKVD -QGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKVLRYTISHSDNNGCDILIDVLGGT -KEVQKFINKQGIKDFVIKVNEQQMRT-WENLYVNTTTPLATTVLLEKFFKGQILKESTTK -YLYQIMVETSRGLTWMKAGLPKNTELAHRTGMSGTNAMNDIGIVKLPNGKHFILSVYLKN -ITEKQEDTEKVIADITKATWDYf ->[subseq from] Beta-lactamase n=2 Tax=Legionella waltersii TaxID=66969 RepID=A0A0W1AM06_9GAMM --tDIQKRISAIEKSSNAIIGVTAIYVEKNKVI-SHNGSQRFFMASTIKLPIAIALLHRVD -EEKESLNRIVKLNAKHSVPGSGVLHYMFEKNISMKQILKYMLINSDNSASDVVLQAAKGP -SAVTKRMYALGFKNIVINRSIIQMLMRFQNDVRDTTTPDDMAKLLVKLYKGDVLSESSTN -LLLNIMESCRTGRSRIRGLLPPRVKVAHKTGTWGYRFTSDVGIITLPNKGHIAIAVYIKS -KAVSDYPRSRAIAQISKAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter tepidarius TaxID=60454 RepID=UPI000A3B4682 ---RLAAELMIIEAAGNGTLGVALFNTVTGASV-GLNQDRRFGHASSFKFSLAALLLQRHA -AGLIDADRDVMWSEADMLPYAPFTRERMASGATLRELARAAQTTSDNPAANILLRELGGP -VALTAFWRSIGDEVSRADRYEPALNNVPTGEFRDTTTPAAMARNVARIIYGDVLPEKERA -ELKGWMIETRTGARRVRAGLPQGWIAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYFRA -RQRELASGETTLARVGRVI---- ->[subseq from] class A beta-lactamase n=1 Tax=Vibrio vulnificus TaxID=672 RepID=UPI000D4E6770 ------------EDELGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudofrancisella aestuarii TaxID=2670347 RepID=UPI000E65737A ---QVQNKISRVQGKFGGKVGIYTIDRNDWKNF-KYNENFQFPICSVYKFLVVGAILKESM -TNPDLLDKKIKIHEGDIIGYTPVTSKNINKSLSVKDLSKAAI-LSDNTAANLLINELGGL -KKLNEFIISLNDKDTIITANEPNINNINLHDNFNKTSPKSIARDINKIAFDDVLDKRHQK -LFRKWLKENDTGKNRIAYSLPEGWQIGDKTGTCEYGSTNDVAILWPKGKKAIIMSILYTQ -ADKNAKPKDEIIQATSKIVLDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium shigense TaxID=297244 RepID=A0A1N7IQZ5_9FLAO --qQLKKDLQQIISTKNATFGISVKGIEDQDTL-SINGNKRMPMMSVFKFHIALTVLDLVD -KGKLQLNQKFFIKKEELLAWSPMRDEFPEGNLTLDQLLRYTVSHSDNNGCDILLEIIGGT -QTVQKFINKKGIKDFTIRFNEQQMSGE--NLYTNTTTPIATTELLEKFYKGKVLKENTTR -YLYKIMVETSRGLTWMKAGLPEGTELAHRTGISGRAAMNDVGIVTLPNGKHFILSIYLKN -ITEDRVVTEKTIADITKTVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Anseongella ginsenosidimutans TaxID=496056 RepID=A0A4R3KL40_9SPHI ---TLESQISHIAKEVNGRVGVCALVLETGEAV-SYNGGERYPMQSVYKFPIAMAVLEKVD -RGELTLDQQVRIDTTEYIPHSPLRDKFPGGTLTVRQLLHYNTAESDGTACDVLLRLLGGT -KKAQRYVRRLGIKNMAIATTEQIQVANDLIQYRNWSTPKAMTELFRIFYQDKPLSEESTA -LLMEHLSPSGVWNRRIKGLLPPGTPVVHKTGTAGTRATNDAGIITLPNGNHVAITIFLAD -SHAVQKDREATIAKIARAVFDQy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium elymi TaxID=395936 RepID=A0A3D9DDU8_9FLAO --qQLKKELQQIISTKNATFGISVKGIEDKDTL-SINGNKRMPMMSAFKFHIALAVLDQVN -KGKLRLNQKFFIKKEELHPWSPIRDGFPEGNLTLDQLLRYTVSHSDNNGCDILLEIIGGT -QTVQKFINKKGIQDFTIRFNEQQMSGE--NLYGNTTTPIATTELLDKFYKGKILKEATTK -YLYTIMVETSRGLTWMKAGLPEGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSIYLKN -ITEDRAATEKTIANIAKTVWEYy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDCB5F5 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMAGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. IC081 TaxID=304378 RepID=A0A514WM39_9SPHN --nDFERRLAGVAEASQGRIGVAAVDLSTGRTV-DVLGSQRFPMASTSKVAIAATFLDGVD -KGKWSLSSEYPLMIPVASASSPIAPVRPGAYMSARQLLELMITRSNNYATDALLKVVGGP -AAVNAWVRRAGIEDWHIDHDIATLVRAKVVDKRDSATPLAMVELLTGIYQGKWLTPSSRS -VLMGAMGRCVTGRNRIRAGLPSGVTVSHKTGSLNN-TSSDIGFIETADGRAYAVAIYVTG -QG-SRPAREARIASIARTLYEGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9I1_ECOLX -------------------------------------------------VMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNH-------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Myroides guanonis TaxID=1150112 RepID=A0A1I3PIS6_9FLAO --eNLRDNIEAITKSKNAIVGLAIQGTNPEDTL-SIRGTEHFPMQSVFKFPIALTMLSEID -KGNFSLDQKITISKNELLPWSPLREEYPEGGLSIANILRYTVMSSDNVGCDVLLRKLGGP -IAVENYFHKRGFNDFEVKINEETMQNNWDMQFLNWTTPKEANNILKAFYENKQLSHKNHE -FIWNIMKETETGKTRLKGQLPKGTLVAHKTGWSGSAAVNDIGIVFLPNGNYFYISIFITN -SIEDTETNEKIIADIAKSAWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter cryptus TaxID=196588 RepID=UPI00041C0972 ----LAAELRIIEAAGDGTLGVELFNPVSGVAV-GLNQQQRFGHASSFKLSLAALLLQRHA -AGAIDADRRVTWGKADLVGHSPFTLERLPRGASLRELARAAQVTSDNGAANILLRALGGP -AALTAFWRSLGDSVSRLDRYEPELNLVPASEFRDTTTPAAMACTLARIVYGEVLPEAERA -ELKGWMVETQTGMRRVRAGLPKGWVAGDKTGTSGY-CYVDIGFAEGPKGGPITFACYFRA -RQEMLPRGEQVLARVGRII---- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter salegens TaxID=1737568 RepID=UPI000B330C8B ------RLVAQLADGSNGRIGVAAVDLSTGQEV-GVLGDQRFPMASTSKVAIAATYLEGVD -KGRWTLTRELPLLVPVRSASSKAAPVKEG-QYTALELIDLMLTRSNNAATDSLLHAVGGP -AAVNDWARRAGIKGFNLSRDIATLVRASHIDIRDSSTPRDMVLLLTGLYQGQWLSAESRR -VLIDTMERCRTGTHRIPALLPENVRVAHKTGSLNN-TSSDVGIMMAPDGRSIAVAIYVTG -QG-SRANREAKIASIARAIYDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9D9_ECOLX -------------------------------------------------VMAVAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNH-------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. KBS0721 TaxID=1179672 RepID=A0A1S8ZZJ0_9FLAO --nELRQQLNQIISSKNATVGISIKGIEDKDTL-SLNGSLKAPMMSVFKFHIALTVLDKVD -QGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKILRYTISHSDNNGCDILIDVLGGT -KEVQKFINKQGIKDFVIKVNEQQMRT-WENLYVNTTTPLATTVLLEKFFKGQILKESTTK -YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN -ITEKQEDTEKIIADITKATWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000739857D --qELKNQLQQTIASKKATVGVSIKSIEDKDTL-NINGNLKMPMMSVFKFHIALTVLNEVD -KGKLKLDQRFFIKKEELLEWSPMRNDFPNGNVTLDQLLRYTVSHSDNNGCDILLNILGGT -EKVQTFINQQGIKDFTIKVNEQQMAT-WDNLYINTTTPIATTLLLEKFYKGKVLKKDTTK -YLYQIMTETSRGLTWMKAGLPEGTELAHRTGISDRAAMNDIGIIKLPNGKHFILSVYLMN -ITEKREDTEKIIADIAKATWNYy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LPJ1_9BACT -------DVTQIASLAKGHVGASAVVLETGETVaSLNAQDHFPMQSVYKLPISMAVMKQVD -AGKINLDQKVAVTKGDFVRYSPIRDRNPNGTITVSELLRFAISESDGTASDVLMKLAGGR -IPVQMYVTDLAVTDMIVLNTERELGQDWQVQYRNSATPEAAIALLRALHEKRGLSESSQA -LLLKYMIESTPGTKRIKGLLPTGTIVAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVSD -SPADEATREGVIAKIAKAAWD-- ->[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga sp. O9 TaxID=1233460 RepID=UPI00136FF661 ------RAYATIASGIKGTVGISSVVLETGAAA-GLRTNEHFPMQSVYKFPIAMAVLHEVD -KGRLSLQQPVRVLPSDLIPHSPLRDAHPAGNYSIAELLRLNVAESDGTACDVLLRLLGGP -EKAGQYVHSLGITDISIATTEQVQVPDEMVQYRNWSTPAAMTALLKKFYTGKLLSDSSYH -FLLHLMVTSTPGAKRLKGLLPKDAVVAHKTGTSGTRATNDAGIITLPNGHHLLISVFVKD -ARADLAQREATIARIAEATWNYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia sp. 251B4_12EESBL TaxID=1535668 RepID=A0A076V860_9GAMM ------------------------------------------------------------- -----LLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWIVGDKTGSGDYGTTNDIAVIWPANHAPLIL------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000D19B391 ----AAKSFDQIEQDNDTIVGVYGINTSNGKVI-QHRSDERFAFASTYKAISSGILLQNTP ---TSELNKKITISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI -KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKMAATTLNHLLASENMSRPNLE -LLKHTMIHNETGDTLIKAGASKDDVVGDKSGQGTYGSRNDLAFVYPENQKPIILAIYTKK -TDKDAKPDDKVIQTAAEKAIK-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF45_9BACT ----LPDQIERITAGKHALVGIAVAAADGKEVL-TIQGDKRFPMQSVFKFHIALAVLSAVD -EGKFTLDQQVEILKKDLLPWSPLREEFPEGGFSIQSLLGYTVSQSDNVGCDALLRLLGGP -QVVEGFIKKNQISDISIQINEETMQSNWDLMFQNWTTPRAANEVLVKFYSQRQLSPESHA -FIWRLMRETQTGAGRLNGQLPEGTTVAHKTGSSGTAAVNDIGIIFLPDGNYFYISTFITE -STEDEATNDRLIADIARVCYDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEV2_9BACT ----LPDQIERITAGKHALVGIAVAAADGKEVL-TIQGDKRFPMQSVFKFHIALAVLSAVD -EGKFTLDQQVEILKKDLLPWSPLREEFPEGGFSIQSLLGYTVSQSDNVGCDALLRLLGGP -QVVEGFIKKNQISDISIQINEETMQSNWDLMFQNWTTPRAANEVLVKFYSQRQLSPESHA -FIWRLMRETQTGAGRLNGQLPEGTTVAHKTGSSGTAAVNDIGIIFLPDGNYFYISTFITE -STEDEATNDRLIADIARVCYDYf ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. YR388 TaxID=2135665 RepID=A0A3M0FFM7_9GAMM ---VLQHALEALAQRAPGTLGVAVLDLRSGAAA-GVDADRAFPMMSVFKAPVAAAVLARID -EGSLSLQQSVTVTREQVMGGSPSIGAHFRGEFTIDELLKAAVSESDNTAVNALIRAVGGP -GVVTTYLHAHGIDGMRVDMDEAGIAQAFLADPRNRSTPDAAIAFLRKLVQGELLSPVSTQ -RLLAMMEAQTI-PNRLRAGLPAGLRFADKTGTSGTAAFNDIGIIRWPDGRTVLVAAFLLD -SPATDSQRAALFADIARTVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea thiooxidans TaxID=53254 RepID=A0A0Q3I6M1_9BRAD --dKLDKGIVAIEAQAEGRLGVALLDLRDRKQW-SHRGTESFPLQSVFKLPLAVAVLQQVE -AGKFKLDQPITVTRKDFSLHSPLAKTFKGERYPLSELVRLAAGQSDNTAADLLMREIGGP -QVVTNMLRDGGITGISIDRYERQFQPAALKDKRDAATPEASVLFLEAFAKGNWLRPAHTA -FIEKIISETKIGADRIKAGLPAGSRLAHRTGLGMNHATNDIGIATLPDGRRFAIAIYLAG -SRADANEREAAHAAVARLAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Serratia marcescens TaxID=615 RepID=UPI0009B528F1 -----------------------------------------PPLDSTVKSIACANVLAKVD -AKKLSLNHSMVVTKKNLVTYSPVAKDYMNKPFTLEQACKAANEYSDNTAANFAIFSGGGP -EALTAFMRSIGDTVTRSDRYEPELTVNSVDDLRDTTTPDAMSKSIKKILTGEVLSDSSKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGIRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] Beta-lactamase class A n=2 Tax=Tenacibaculum sp. MAR_2009_124 TaxID=1250059 RepID=A0A1H4SIC1_9FLAO ----LKQQIHKVLKNKKAHVGVAIEGVHPKDIV-SINGDDHLPMQSVFKYHLALAVLHQVD -LGKFDLNESISIDKKTIAKWSPLRKKYPNGAVTLAEIIKYTVAWSDNIGCDLLFELVGGL -KAVENYLHKIGIKDIAIVHNEINMQAQWDRQFENWTTAKAANKTLKLFYKNNLLSKKSYN -FLLDVLKGTQTGKKSIRGFLPKDTIVAHKTGHSGTGAVNDIGIVFLPNGSHFYLSVLVSN -STEPDTTNQKIIAEIGKLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SSZ0_9BACT --sELENRIDSLLNGKKATAGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Class A beta-lactamase n=1 Tax=Empedobacter sp. MRS2 TaxID=2491114 RepID=A0A4Z1BQY8_9FLAO --eSLRTEINQIISSKNLTAGISLKNLKNKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD -QNKLQLNQQFFIKKEDLLPWSPILEDNPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT -KTVQNFINNQGIKDFVIKVNEKEMQT-WDNLYLNTTSANATTKLLEKFYSNKVLKKTSTT -YLYQLMVETSRGLTWMKAGLPTNTELAHRTGISDTNAMNDIGIIKPINHQPIILSIYLKN -ITEERTETEKVIADITKAVWNYy ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia ATCC 25015 TaxID=539329 RepID=C6YWK1_9GAMM ---TLDDSFKNLEDEYHGKLGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QHKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWTIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -PSVKAPSNEKIIQQASKLVSE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium sp. 90 TaxID=2135622 RepID=A0A4R1JS72_9FLAO --nELRQQLNQIIASKNATVGISIKSIEDKDTL-SINGNLKAPLMSVFKFHIALTVLNLVD -EGKLSLTQEIFIKKKDLHEWSPMKEDYPDGNLTLDKILRYTVSHSDNNGCDILIDLVGGT -KVVQKFINKQGIKDFVIKVNEEQMKN-WKNLYINTTTPLAATELLENFYKGEILKEETTK -YLYQIMVETSRGLTWLKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFIISVFLKN -ITESKENTEKIISDIARATWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Nocardia crassostreae TaxID=53428 RepID=UPI000B0674D5 ------------------------------------------------------------- -------------TEADLLEHAPFTSQHVTTGMTIRDLCDAAIRYSDGTAGNLLLRELGGP -AALTAFTRTLGDSVTRMDRIEPDNTTALPGDPRDTSSPRALGTDYQQIVLGTALPPDQRT -FLRDLLERNTTGNQRIRAAIPQGWPVADKTGTGDYGTLNDIAITWPPNTPPLVIATMSDR -PTANAEYRQALLADAAALVVS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera ascorbata TaxID=51288 RepID=A0A3Q8GRR3_9ENTR ------------------------------------------------------------- ----------VEIKKSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPTSWVVGDKTGSGDYGTTNDIAVIWPEDHAPLIL------ ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Xanthomonadaceae bacterium TaxID=1926873 RepID=A0A4Q2XS80_9GAMM -------ELRALEQNANGRLGAYVLDPVRGTAF-GWRENERFTHASSFKMSLAAMLLSKAD -AGQIDLRETLLWTKEDMLSVSPVTTVNLGKGLSVRELARATLVTSDNTAANVLMRRFGGP -SQLTAFWRSIGDKSSRLDRYEPELNVTPPGTDLDTTTPAAMAATTAALVHGTILAADSRA -MLRAWMAEVKTGQDRIRSGFPTDWISGDKTGTGIGKTTH--------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. SCN 62-14 TaxID=1660099 RepID=A0A1E4B2J5_9SPHN ------------MDSLGGTLGAEIFEPETGMAV-GINQDRRFGHASSFKFSLAAMLLAKHA -AGAIDADKKVMWSERDMVEHAPFTRERIASGATLRELAEATQVTSDNPAANILLRALGGP -AALTGFWRSLGDEVSRIDRFEPDMNNVPEGEFRDTTTPAAMARTVARILYGDALPEAERA -QLRQWMIETQTGARRVRAGLPKDWVAGDKTGTSGTSNFIDIGFVEPGKGRPITFAAYYRA -RSEVSASAERVLMRVGRVI---- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. Aq135 TaxID=1191734 RepID=UPI000D561AFE ----LLKKIEQIVSDKNAVVGVSIIGNNGKDTL-SLYGDKRFPMQSVFKFHIALAVLSEVD -KGVLSLDQIVEIDKDELLPWSPLRDENPNGGFTIKRLIQYTVSHSDNTACDVLIRLIGTP -KTVEEYIKKSGIEDIQITFNEEKMQAKWENMFQNWTTPNAASETLKIFFENNLLSKSSYD -FFWKTNTETTTGKGRIRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPDGKYFIISVFVTD -SQENFKTNQEIIAAIAKATYDFy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD2C84E --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5A2BA ------------------------------------------------------------- -----------------------VTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTDFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus sciuri TaxID=1296 RepID=A0A411KFM3_STASC --nSTNNDIEKIEKKYGANVGMYALNTQNGKEL-SFNENKRFAYASTLKAISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTAKNKIIDELGGY -EQVKTRLIDLGDTTTYPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD -FLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK -DR--------------------- ->[subseq from] class A beta-lactamase n=1 Tax=Azospirillum sp. B4 TaxID=95605 RepID=UPI00034DF259 ---ALQARLDQLAHDFPGRAGIAVRDPATGAVA-GVKAQERFPEQSVFKLTVAIALLDLVD -KGAMDLKRKVTLYPRDRSVWQPLAKNITPAGTTLDDLMARMVADSDNIAADTVLRLIGGP -AAVQAALTARGLDGIRVDRDERHLQSAYLNDPRDTAQPAVMALLLERLDKGELLSPASTR -RLLDILDHTTTQPNRLKAGLVAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS -VQGPRERADAFIASVARAVVASw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales TaxID=356 RepID=UPI00082A041E ---RLSREIVAIERDANGRLGVALLDLKDRSLW-SHRGSERFPMQSVFKWPLAIAALQAVE -AGKLRLDQPVTIKRSEFSLHSPLAKAFKGEAYPVRELIALAAGESDNTAADILMREIGGP -RAVTAMLKAGGITGISVDRYERQFQPAALKDPRDSATPEASVAFVEAQAKGNWLREPAHS -ALIDITLETKSGPDRIRAGLPQGARFAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG -STADAKAREAAHAAVARLAVS-- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobium ummariense RL-3 TaxID=1346791 RepID=T0J0V3_9SPHN ---RLIAELERFTKLSDGTVGIAVRDLSSGEEL-AVNGDTLFPMASTYKVAVAGRIFSLID -AGQMTLDTMLPLDPA-LVSEGGVADLHPGAALSVHNFLELMLTRSDNNATDVLVARAGGP -QAVNAWVHGIGVKGLRVDSNTAGLLYTFAQDPRDTATPRAMNQLLSAIQLGKALKPASTA -ALLAIMERCRTGQGRLPAMLPPGTRLAHKTGSLN-GLGNDVGIVSLPDGRIFAISVFVMK -DHEGHAMRDRIMAEAARAAYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Rhizobium meliloti (strain 1021) TaxID=266834 RepID=Q92Y19_RHIME --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia fergusonii TaxID=564 RepID=UPI0011198FFE ------------------------------------------------------------- -------------------------AKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000B49FD89 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. BPTF-M16 TaxID=2169535 RepID=A0A411ZE97_9SPHN ---RLAAKLNIIEAAAGGTLGATFLNTSTGISL-GINQSARFGHCSSFKLSLAAMTLWRDE -QGLDDAERRVTWTQDDLMFVSPFTTRRLDEGATLRELAEFTQKYSDNAAANILLREFGGP -ETLTDFWRMLGDDASRLDRSEPALNNVPPGENRDTSTPDAMARTVSALCFGDTLSEDGRD -TLKQWMIDTPTGAKRVRAGLPEDWLAGDKTGTSIGSLYVDIGFVEPPNRPPLTFATYYRA -RETHDPASQKVLADVGRVLAE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sediminis TaxID=2070536 RepID=UPI000CA05BA2 --nTLRQKINQVLEGKSTTVGVAITSSNPNDTI-SIHGDMHLPMQSVYKFHLALAVLHQID -QGKFNLDEKITIDQKLVDSWSPLRKKYPNGAISLEELLTYTVSLSDNLGCDVLFKLLGGT -EAVQSYINEIGIKDIAIIHTEFKMQAEWDRQYENWTTAKAANKILQLVFEDDLLSPKSYD -FIINVLKETKTGKKSIRGLLPAEAIVAHKTGHSGTGALNDIGIIFLPNGTHFYLSVLVSD -SMENNETNQKIIAEIAKLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. KEM-5 TaxID=2486356 RepID=A0A5S3PQH0_9SPHN ---RLAAKLAILERALGGTLGAAFYDVEQGLTL-THNAELRFPLCSTFKFSLAAMVLMMEQ -NGTLDTSQHVTWQDSDLLSHAPFTRERGAQGATLLELARAAQVASDNTAANLVLDRVGGP -AALTAFWRALGDDVSRLDRMEPQLNAVAEDELRDTTTPAAMVSTLTKLIASDPLGAQRQA -ILRQWMQDTATGSKLVRAGLPPAWEAGDKTGATDAGARADIGYTLSPGGTPVMFALYYRA -DRPPQTEISRTFAEVGRVL---- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525JKP1_9CAUL --kRLDTEVAAIAQRAPGALGFALMNLESGEFW-VRLGDRAFPMQSVFKLPLGAAVLSEVD -AGRLRLDEILTIRAEDLSPWSPIADAWPGRAYSVQELLAAAVGDSDNTAADLLMKHIGGP -GVVSAWLQSKGITEVRVDRYEREVQPAYMADPRDSATPEGMLGLLRRLDQDELVSPASTR -RLLTLMVQTPRGGDRIKAGLPKTATFAHKPGTSGNAAFNDVGIFTLADRRSYAVAAFLTG -STATDAERAALFADLGRTAA--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Taibaiella sp. F-4 TaxID=2301235 RepID=UPI000E573020 --eALRQSLQGIVDTARAHIGVGVLDLDTGDKL-LINGNDSFPMQSVFKFPLAIAVLHQME -QEKKPLSTPVSLSRKNMEAWSPMLRDHKEEQITLGELLSYSVKKSDNNACDALFRLADGT -LVVDQYIKSLGIKGMAIKATEAEMRMAWPVQYTNSCRPDAMLQLLQQFYRKKLLSPEHQQ -FLWQIMTDSENPADRIKGLLPAQAVVTHKTGTSDTAATNDVGIISLPNGRHIALVVYVSD -FKGGTARGAHLIAIVAKAVWDHy ->[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. SYW-2 TaxID=2610886 RepID=UPI00123DB259 ---TLDDSFKNLEDKHHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QHKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVKEIGGL -EKLNKLVTKLGDKDTIIKNDEPEINRTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN -PSVKALSNEKIIQQASKLIAD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chishuiella changwenlii TaxID=1434701 RepID=A0A1M7ALQ3_9FLAO --nNLKEDLQQIISSKNATVGISIKEIETNDTL-SINGNLSAPLMSVFKFHIALTVLNEVD -KGKLKLNQKFFIKKADLHAWSPIQEKFPNGELTLDELIRYTVSHSDNNGCDILLNIIGGT -DVVQKFINEKGIKDFTIKVNEQQMSH-WENLYKNTTTPLASTELLEKFYKNKILKKNTTE -YLYQVMIETSRGITWMKAGLPKNTELAHRTGMSGTNAMNDIGIFKLPNGKHVILSVYLKE -ITESFEDTEKIIADITKAVWNYy ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium nitrogenifigens TaxID=1617283 RepID=A0A521CXB6_9FLAO --nELRNQLQQIISSKSATLGVSVKGIENKDTL-SINGNLKMPMMSVFKFHIALAVLHKVD -EGKLNLTQEIFIKKKDLKEWSPMKVDYPEGNLTLDKILRYTVSHSDNNGCDILINLVGGT -NYIQKFINDQGIKDFVIKVNEDQMKT-WKNLYVNTTTPIATTELLEKFFKGEILKQETTK -YLYQIMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKD -ITEKREDTEKIIADVTKAVWDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000D1DA11F --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000FD994F0 --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGGSGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEERAAMIAAAARAITAAy ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9H5_ECOLX ----------------------------------------------------AAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter pelagi TaxID=994320 RepID=UPI001325ACCD ---RLEAQFRLIEVATGGTFGIAAYDTRADRMI-AYRGDERFALASTFKASLAAFAMTEAQ -AGRIDLDERTFWTQADFVFHRPFTGERVDSGATWRELAYAAQTQSDNVAANLLLKRLGGP -EALTAFWRSLGDPVSRLDRFETDLNRVPPGTVEDTTTPATMARTLATLLFAEPLVPERRQ -ELRRWMAESVTGLQKIRAGLPRGWEAGDKTGNSSPQVRGDIGFVIGPLDAPVTFAAYHRS -PLLDDAPVDAGFAAIGRA----- ->[subseq from] class A beta-lactamase n=1 Tax=Francisella sp. XLW-1 TaxID=2610887 RepID=UPI00123CC7A1 ---TIDDSFNNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -ENLNKLVTKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN -PSVKAPSNEKIIQQASKLVAD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium polynesiense TaxID=1325933 RepID=UPI00058C5FA2 ----LENEIKNFISNEKGRISVAVKNLKTGETI-KINENEVFPSASTIKLVIMSELLKNVK -EGRLKLKDTVEITKEDITGGDGIIKENLNHKFTLEELMTLMIIISDNTATNILINLL-GI -DKINAMAESLNMKNTKLQRKMMDLEAA-KEGKENKTTAEDLANILELIYTGKNISEEYSL -MMLNILKRQQV-KGRLDLYLPEEVTIAHKTGDLDK-LEHDVGIVFLKDSD-YIICVLTKD -TD-TNKDGREIIGKISKMVYDEf ->[subseq from] Uncharacterized protein n=2 Tax=Flavobacterium rivuli TaxID=498301 RepID=A0A0A2M2D4_9FLAO --tELREQLEKIVADKKATVGISVLGLEDGDTL-SMNGDRNFPMMSIFKFHIALTVLKKVD -NGALSLKQKIFISSKELLDWSPIKDKYPAGNLTLDEILMYTVSHSDNNGCDVLLRLIGGT -QVVQEYINTLNIGSFVIRYNEEQMASG-ELAKVNTTTPLATTKLLSLFYNYKLLEKKTTR -YLNELMEQNSRGKALIKGKLPTGTKVAHRTGMSGTDALNDVGIITLPNGKHYAVAIYLNN -ITENKETAEGLIADVSKSVWDYf ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127SLQ7_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. LASN5T TaxID=2491021 RepID=A0A3N9RS16_9SPHN ----IQQQIAAIASQSRGRIGVAAMDLDGGGQI-FLNGDMPFPMASTAKIAVAATFLEGVE -QGRFRLDQRFPMMLSVAERRSPIAPVRAGPVMTAQELMELMITRSNNQATDGIIAAIGGI -APVNQWLTRKGIVGQRLDHTMATLVRATVIDTRTSSTPRAMLALLAAIDRGGALNPESRA -VLLDTMTRTSTGRNRIRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAMVVFVAG -PEG-HAPQSALIAQVARVLYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces subbeticus TaxID=293890 RepID=UPI0003B77BF3 ---RMNEALRALEQSNAVTIGVTALVHGSRHAF-RYRGNELFPMCSLFKSLAAAALVQARG -YDEVYWSTPIPFTIADRVGDSTKLNT--DTWATPEELADAAIRYSDNTAGNLLLRELGGT -QAVTTFARSLGAQRTRLDRAEPEVNEALPGDERDTSTPDDIAFLFELLMLDHGAGALTGA -RLQEWMLRNTTSGRRILAGLTPPFELADKTGLGGYGVVNDAGIVWRPGEAPVTLAIMTRT -DRADAPNNQDVLAEVTRIVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. Mgbs1 TaxID=2485489 RepID=A0A433WLE2_9BACT ------RAYATIASGIKGTVGISSVVLETGAAA-GLRTNEHFPMQSVYKFPIAMAVLHEVD -KGRLSLQQPVRVLPSDLIPHSPLRDAHPAGNYSIAELLRLNVAESDGTACDVLLRLLGGP -EKAGQYVHSLGITDISIATTEQVQVPDEMVQYRNWSTPAAMTALLRKFYTGKLLSDSSYH -FLLHLMVTSTPGAKRLKGLLPKDAIVAHKTGTSGTRATNDAGIITLPNGHHLLISVFVKD -ARADLAQREATIARIAEATWKAy ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WKG3_9BACT ---KLERQIAAIAPLSGGTVGVAATHLESGRSV-FVNADDQFPLASTYKVPIAIQAFKLVE -EGKLSLDQMVPVLPTDIHIGSEWNKLFQAPGLSFRNVIEPMLIFSENSATDLALRLVGGG -EAVTARLRALGINDMRIDRSTADVIAYYANDPRDHGSPRAMLTILTRLWKGELLNKANTA -YMLDIMYRCETGQGRIKGMLPPGTRVAHKTGTFP-GTTNDVGVIDLPDGTHVAIAVYIKK -SSVPGADLEATIAQVSRAAYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649VYG8_ECOLX ------------------------------------------------------------- ------------IKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLI------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Porphyromonas macacae TaxID=28115 RepID=UPI001269F717 ---RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD -KGALRLEQEIRISSTDLLSWSPIRNKYPKGTMPLSEVIRYTISESDNNGCDILLQLIGGT -TAVEEFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD -FLWKVMVDTSTGGNRLKGQLPEGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN -STEDIKTNEKIISDIARKVWEYy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8Q1W2_9BACT ---SVKQEVVNAAKASGGEMGFAASHIETGRRL-TLNSSGRFPMASAYKLPIAIQMLTLVD -EGKAQLERIIKIEPKDIRPGVPLTDKFNAESVSVGDLLEMMLTVSDNTASDLILRLAAGP -EAVTARMRSLGIEDMSIDRSTIEHVFQYGRDLRDTSTPDAMASLLVHVYRKNLLKPETVK -LLLGIMRRCQTGDTRLKGLLPAGTELAHKTGTAM-GIINDVGIITLPNGGHIAIVVFIKG -SKSSVAECEHSIAEVARSAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Porphyromonas macacae TaxID=28115 RepID=A0A0A2E3C2_9PORP ---RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD -KGALRLEQEIRISSTDLLPWSPIRNKYPKGTMPLSEVIRYTVSESDNNGCDILLQLIGGT -TAVEKFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD -FLWKVMVDTSTGGNRLKGQLPKGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN -SAEDIKTNEKIISDIARKVWEYy ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium taichungense TaxID=295069 RepID=A0A1H8CLF9_9FLAO ----LEQKIDSIIQDKNATVGISVLGFEDGFKY-YKNADKRLPMQSVFKFHIAVALLNYVD -KGKLSLDQKVLLDKTNLFEWSPLRDKYPDGVVPLSEILEYTVAKSDNNGCDIILKLLGGT -QTVQRFMDSKGVKGFQIKYNEAEMRKDWNIQYKNYSTAASATDVLKKFYDGKLISRKSTD -YLMQIMFSTSTGKNKLIEQLPENTPVARKTGASGTGAENEIGIVTLPNGKHYAIAVFVSN -STETNVVNCKMISDISKSVWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BIN7_9BACT ------------------------------------------------------------- ----------------------PVTKEHLKEGMTLGGLCAAAIEQSDNTAANLLLDAIGGP -AGLTNLARNLGDNATRLDRKEPELNSAIPGDERDTTTPGAICSDMQRLLLGDALSEASRR -QLEDWLQHNETGEQMIRAGVPNNWIIGDKTGRGSNGATNDIAIMRPPDRAPILLAIYSVG -STATANDREEAIAEAAKIVAETf ->[subseq from] Beta-lactamase n=1 Tax=Akkermansia sp. CAG:344 TaxID=1262691 RepID=R7E586_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINIRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. SLB01 TaxID=2665645 RepID=A0A5Q3R0B2_9FLAO --nELRQQLNQIISSKNATVGISIKGIEDKDTL-SINGNLKAPMMSVFKFHIALAVLNKVD -EGKLSLTQEIFIKKKDLHEWSPMREDYPDGNLTLDKVLRYTVSHSDNNGCDILIDLVGGT -KVIQKFINQQGIKDFVIKVNEDQMKT-WKNLYVNTTTPLATTTLLEKFFKGEILKESTTK -YLYQIMTETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKN -IIEKQEDTEKIIADITKATWHYf ->[subseq from] Class A beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-14 TaxID=2013660 RepID=A0A2N3DBB8_9PROT ---RLAAELRLIEAAAGGTLGVEIYNTVSGQSV-GINRDRRFGHASSFKLSLAAMVLARHA -AGTIDADRRVTWGEADMIAHAPFTRERIGSGATLRELARATQITGDNPAANILLRALGGP -AALTAFWRSIGDDVSRLDRIEPELNFVPAAEFRDTTTPAAMARTVAKIVYGEVLPEAERA -ELRQWLIATETGLRRVRAGLPEGWIAGDKTGTSLGSLYVDIGIAEGPKGPPITFAAYFVA -REHDDPAAELALSRIGKVIAE-- ->[subseq from] Serine hydrolase n=1 Tax=Sinorhizobium sp. M4_45 TaxID=2037901 RepID=A0A2N8JRJ3_9RHIZ ---RLRLELETLADAHPGRVGICVQD-QPKSPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD -EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGT -KAIQAFLEKAGLTGVRIDRTERELQTAYIKDPRDTATPRGMAAFLYSLASGSLLTAGSTE -FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE -SRAGQAERAAVIAAAARAITAAy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. ACN6 TaxID=1920426 RepID=UPI000BB37870 ---DLRKNIEQIIASKNATVGVSMKGIEDKDTL-SINGTLNAPMMSVFKFHIALTVLNQVD -NGILKLDQKFFIKKEELLPWSPMREEFPDGNFTLDQLLRYTVSHSDNNGCDILLRIIGGT -QTVQKFINKQGITDFVIKVNEQEMS-IWENLYLNTTTPLATTELLEKFYKGQILKKATTK -YLYQLMVETSRGKTWMKAGLPANTELAHRTGVSGTNAMNDIGIVKLPNGKHFILSIYLKN -ITEEMEDTEKIIAAITKAVWDY- ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Bythopirellula goksoyri TaxID=1400387 RepID=A0A5B9QFY6_9BACT --eDLSSRIQPLIDAFDGEVGVMVKQLETGETF-EYSSTVPMPTASLIKLPIMIATYKAID -SGKLDLAQKITLKAEDKVPGSGILAEHFSDGLPLKDAIHLMIVYSDNTATNLVIDQV-GL -PRTTEVMKELGCDETVLNSKVFRRDTRSKKYGLGSTTAKEMVSLLEKLQAGQLLSKQASK -QMLAHLRACND-KTKFSRLLPPEIVVAHKTGSVSD-SRTDAGIIESPGG-PIALCVLTTN -IANDDNAAELLCSNIAKAAYDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sediminis TaxID=1679494 RepID=A0A5B2UC15_9FLAO ----LEQKIHSILKNKKATVGVSVLGFENSFKY-DKNSDKKLPMQSVFKFHIAAAILNSVD -QGKLSLDQKIVLNQSNLLEWSPLRDKYTGSNIPLSEVIEYTVAKSDNNGCDILLKLLGGT -QPVQKFMDSKGVKGFQIKYNEEAMHKDWKVQYENYSTTKSAVDVLKKFYDGKLLSKKSTD -YLMQVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYALAVFVSN -SMETDAVNCRMVSDISKEVWEYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHS7_9BACT --qTLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REKIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYYNWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. GH3-15 TaxID=2545755 RepID=UPI0010F62AEB ----LARQIAQLADGSQGRIGVAALDLSTGREI-SILGDQRFPMASTSKIAIAAAYMEGVE -QGKWSLTSEFPLLWSVRSTFSTAAAPVRKGELSAHQLIDLMLTRSSNPATDALLAAVGGP -DAVNDWVHRAGLQDFELTRDIATLVRARHIDTRDSATPETMVQLLTGLYQGRWLSAESRE -VILDAMARCRTGVRRIRGQMPNDVSVAHKTGSLHN-TSSDIGIITAPDGRSYVVAIYVTG -QG-SRGNREQRIASIARAIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. B 225 TaxID=1961849 RepID=UPI000B4BE8B8 ----LEAQIASLAAPAQGRIGVAALDLSTGRTV-SVLGNQPFPLASTSKVAIAATFLAGVD -QGRFRLSDQYPLMVPVRSAYSEVAPVRAGATMSAQGLIELAITRSDNPAADALLAAVGGP -QAVNRWLQGAGLSGMRMDRDIATLVRATTIDPRDSATPLTMVELLGGLYRGQWLSSSSRN -LLLGTMARTVTGKRRMRALLPGEAGIAHKTGTLSN-TASDVGIITTPDGRSIAVAIYVTG -QG-SKAGRDARIASIARAIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. EL138 TaxID=2073156 RepID=UPI000D68C483 ---AARRELAKLEKRIGGRLGVALTDAKGDIAL-DHRGDERFAMCSTFKAPLAFALFDAAD -KGRVDVKKSFAVTENDLVPYAPFVEEQIAAKVTLEQLAKATVKSSDNAAANLILKAIGGP -EAFTDFVRRRGDVITRLDRIEPFLNENKVGDPRDTTSPIAFAKLMHGMMSGKS-RLTNWS -IVYDAMASSKTGLGRIRLGLPYGWPVGNKTGTAGGGAYNDVAIFWPSGDEPRFLTVYTDR -PTASAAIVDRTIAEVAKIA---- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000B498344 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDLLTIRRDDLSVIQPIADIVAERGTSVGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E5I532_9BACT ----LALELTRLGELSGGTMGVGVIHIESGRRV-YVNNNERYPMASTYKVPIAVQLLKRVQ -MKEITLDQMVEVQTYDLHPGSGTLSRFINPGLSVRNLLELMMLISDNSATDIMLDTAGGS -KRVNRILKTNGISGMNVDRSTVRLIAVFSRDKQDTSTPEAMAVLLEKIWNKEILNPEMSE -LLIDIMGRCKTGEDRLKGMLPEETFVAHKTGTIGS-TTNDVGIIELPNKGHVVVAAFVKD -SELEIPERERAIAHAARAAHDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. OV279 TaxID=1500285 RepID=A0A1M4XKL6_9FLAO ---NLRQELKQIISAKNATVGISIKSIEDKDTL-SINGHLNAPMMSVFKFHIALATLNLVD -KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGP -ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSRAAMNDVGIVKLPNGKHFIISIYLKN -ITEKREDTEKIIADLTKATWN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDAF38F --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] VEB-PER_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WZ77_9BACT ---ALVTRLSKLLGPLQPKVGVSVKLAGKQQTS-GWNESAHLPMQSVFKFPIAVVVLSEVD -KGNLSLDQEIDIQKKDLPAWSPIRDDHPSGALTLAEILQYTVSQSDNIGCDLLLKLLGGL -EKVQHYFATHGFTEISVEVTEDDMHRDWNAQFKNWCTPREITRIIEATYEDRLLSESSHA -FLWKIMTETNTGQKRLKALLPADAIVSHKTGSSGTAGTNDVGVIQLPNGRAVYISVFVTD -SKESDEVNERIIAEIGKLVWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00047FD84A --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium 32-64-22 TaxID=1970593 RepID=A0A258GS62_9SPHN ----LAQQIARLADGSAGRIGVAALDLSTGREI-SVLGDQRFPMASTSKIAIAATYMEGVE -QGKWSLTSEFPLLWSVRSTFSTSTAPVRKGEMSALQLIDLMLTRSSNPATDALLAAVGGP -DAVNDWVRRAGLEDFELTRDIATLVRAQHIDMRDSATPETMVELLTGLYQGRWLSAESRE -VILDAMARCRTGVRRIRGQMPDDVSVAHKTGSLNN-TSSDIGIITAPDGRSYVVAIYVTG -QG-SRGNREQRIASIARAIYDGy ->[subseq from] Beta-lactamase n=2 Tax=Porphyromonas macacae TaxID=28115 RepID=A0A379E6T7_9PORP ---RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD -KGALRLEQEIRISSTDLLPWSPIRNKYPKGTMPLSEVIRYTVSESDNNGCDILLQLIGGT -TAVEEFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD -FLWKVMVDTSTGGNRLKGQLPKGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN -SAEDIKTNEKIISDIARKVWEYy ->[subseq from] Beta-lactamase n=2 Tax=Porphyromonas macacae TaxID=28115 RepID=A0A379DF02_9PORP ---RLKSEINRLIKDKNATVGVSIIANNRKDTI-GINENLHYPMQSVFKLPIALTVLSEVD -KGALRLEQEIRISSTDLLPWSPIRNKYPKGTMPLSEVIRYTVSESDNNGCDILLQLIGGT -TAVEKFLSKYELTDISIKASEKEMHETPDLQFRNRATPVSLTKLLTMFYGKSILSQKSFD -FLWKVMVDTSTGGNRLKGQLPEGTRVAHKTGTSGIAATHDIGIIILPTGDPVFISILVSN -SAEDIKTNEKIISDIARKVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Francisella hispaniensis FSC454 TaxID=1088883 RepID=A0A153JBJ7_9GAMM ---QLHDSFKSLENKYDGKIGIFTVDTDNKTNI-KYNENYHFPICSVFKFLLVGAVLDYDM -HNQGFLDKKIPITQDDIGTYAPITAKNIDKSLTISQLNYAAI-LSDNPAANILVREIGGL -QNLNKFIKKLGDKDTIIIADEPKVNHTKPDSNINKTTPKAITKDIYKLAFGNVLDKKHKD -IFIKYLEDNNTGANRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNRQPIGLGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] serine hydrolase n=1 Tax=Qipengyuania sediminis TaxID=1532023 RepID=UPI00105A3556 --sALAQRVAELANASAGRIGVAALDLTTGETV-GVLADQRFPLASTSKIAVAATFLEGVE -QGRWRLDQAFPLLHPTASRFSTSTAPVVAGQLPARELIEQMIVRSSNPATDALLRVVGGP -KAVNAWMRRAGIRDFSIDRDIATLVRAHHIDRRDSATPNAMVQLLAGIYQGKLVAPASRQ -VILGAMSRTVTGKRRIRALIPAGARVLHKTGTLS-GTASDIGFIETPEGHTLAIAIYVTG -QG-TKPARDAKIAAIARGLYDGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. LC2016-13 TaxID=2675875 RepID=UPI0012B8208B --sQLREQLNEIIASKNATVGISIKSIEDKDTL-SINGKLKAPLMSVFKFHIALAVLNKID -EGRLSLTQEIFIKKKDLHEWSLMREEYPNGNLTLDKLLRYTVSHSDNNGCDILINLVGGP -KEIQKFINKQGIKDFVIKVNEEQMKT-WKNLYINTTTPLATTELLEKFFKGEILKENTTK -YLYQIMVETSRGVTWMKAGLPETTELAHRTGMSGRAAMNDVGIVKLPNGKHFILSVYLKD -ITEKQEDTEKIIADITKATWDYf ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium sp. CECT 9293 TaxID=2675057 RepID=UPI00135E4827 ----LHDKINIILLNKNATVGVSVLGFENGFTY-NRNADKKLPMQSVFKFHIAAAVLDFVD -KGKLSLNQKVLLNSSNLLEWSPLRDKYPNGGVPLSEILEFTVAKSDNNGCDIMLKLLGGT -ATVQKFMDSKGVKGFQIKNSEAEMHKDWKLQYKNFSTTQSAVDVLKKFYDGKLLSKKSTD -YLMKVMLSTSTGMNKLVEQLPKNTPAARKTGASGTGAENEIAIITLPNGKHYAIAVFVSN -STESDKVNCKIISDISKVVWDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. OK403 TaxID=1855286 RepID=A0A1I3RTK1_9BRAD --tRLDQEIAAIERQSQGRLGVALLDLKDRKSW-SHRGSETFPMQSVFKLPLAVAVLQAVE -AGKLKLDQPITITRKDFSLHSPLAKAFTGESYPLRELIALAAGESDNTAADNLMRLIGGP -QVVTKMLRDGGIGGISVDRYEREFQPLALKDPRDAATPEASTLFLEALAKGNWLRDPAHA -FLDTVITETKSGPLRIRAGLPLGARFAHKTGAGLNHATNDIGIVTLPNGHVFAIAIYLAG -SKADEKGREAAHAAVAKAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Francisella marina TaxID=2249302 RepID=A0A5C2BWM0_9GAMM ---TLDDSFKNLEDKHHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QHKGFLDKQILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -ENLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAASNDVAIIWPQDKQPFALSVLYTN -PSVKAPSNEKIIQQASKLIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Porphyrobacter sp. AAP82 TaxID=1248917 RepID=UPI000307F6BD ----LAAELRIIEAAGGGTLGVEILDTATGMSV-GINQDHRFGHASSFKLSLAALLLQRHA -AGTIDADRRVMWTEAEMLNPAPFTRARIAQGASLRELARATQTTSDNPAANILLRELGGP -AGLTAFWRSLGDAVSRADRFEPDNNLVPTGEFRDTTTPAAMARTVAKIVYGDALPAKERA -ELKGWMVETQTGLKRVRAGLPEGWIAGDKTGTSGY-NYIDIGFAEGPKGGPLTFACYFRA -RQEMLASGQETLARVGRIITE-- ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium malaysiense TaxID=1348853 RepID=A0A0B1ZF81_9SPHN ----LGQQLASVAEASQGRIGVAAIDLATGREL-DVLGDQRFPMASTSKVAIAATFLEGVD -KGKWSLTSEFPLMIPVSSASTPVAPVRPGAYMSAERLMELMLTRSNNYATDALLKVVGGP -SAVNEWVRRAGIEDWHIDRDIATLVRAQVIDKRDSATPMAMVKLLSGLYQGKWLSPSSRK -ILLDTMSRCVTGKRRIRAGLPDDVQLLHKTGSLHN-TSSDIGIVETADGRVFAVAIYVTG -QG-SRPAREARIARIARTLYDGy ->[subseq from] Beta-lactamase n=1 Tax=Mucilaginibacter corticis TaxID=2597670 RepID=A0A556MI75_9SPHI ----LQAKIGQCAKNANGNVGVYALVLETGETV-SYNGDKKFPMQSVYKFPIAMAVLDRVD -KKQLSLNKKISVTKADYIAHSPLRDKFPNGTIAIKDLVKYSVSESDGSASDVLVRLLGGT -KFANEYVHRLGVKDIAIATTEKIQVENDTIQYQNWATPKAMTSLLNIFYTRHKLSASSRA -VLLNDMITSTPGAKRLKGLLPVGTIVAHKTGTAGTRATNDAGIITLPNGKHLAITVFIAD -SHSSEEIRELTIAKIGKAAFDYw ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. TaxID=1874826 RepID=A0A519QGM9_9SPHN ----FEAQVAALANAQGGRIGVAALDLSTGRSV-AVLGNQPFPMASTSKVAIVATFLEGVD -QGRFRLEDQYPLMIPVPSRDGPVAPVRAGGMYSALNLIEMTITRSDNNATDALLAVVGGP -QAVNRWLRKSGLNDLHIDRDIATLVRARTVDTRDAATPLAMVRLLSGIYRGEWLSASSRA -VLMGAMERCLTGKRRMRALLPEDARVAHKTGTLYN-TSSDVGFIHMPDGRPIAVAIYVTG -QG-GKPNRDARIAAIARALYDGy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter gangjinensis TaxID=502682 RepID=A0A0G9MM20_9SPHN ---QLEMVISQLAEGSQGRIGVAAIDLSTGQQI-SVNGDMRFPLASTSKIAIAAAYLEGVD -QGRWSLTAEYPLLWPVRSEPLSTRAAPVRAGMPAHELIDIMITRSSNPATDALLAAMGGV -EPVNDWMRRAGITEFSLDRDIATLVRRTYIDPRDSATPEAMVQLLAGLYQGRWLSAQSRN -IIIDAMERCRTGRSRIPARMPEGVTVAHKTGTLHR-VASDIGILTGPDGRSIAVAIYVTG -QP-SPAERNGRIASIARALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001295E52E ---RIRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVLAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZE9_9BACT --sELENRIDSLLNGKKATVCIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMAQLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAQTVVGHKTGSSDRNADNDAGLVILPDGRKYYIATFIMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000FD85EBE --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEGRAAMIAAAARAITAAy ->[subseq from] Class A beta-lactamase n=1 Tax=Cryobacterium sp. Sr39 TaxID=1259198 RepID=A0A4R9ALB5_9MICO ------RSVRQLESTSGVMIALSAKNVRSGRQI-NHRATEPVPMCSLFKVLAVANLLRLRG -YEDQYWSTPISFTAADVVVNSPVAAASTSMTMTPNQMADAALRFSDNTAGNLLLRELGGP -ATITQFAQALGARRTRLDRIEPELNEGLPGDVRDTTTAEDMVAIMEALLIDGDAGQLARS -RLQDLMLRNTTSGTRARAGLSEPFELADKTGAGNYGIVNDAGVLWQGQRQTIAMCILTRT -EVASAPNNNDVIADATRLIVSEf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A412DEK7_BACSE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYANWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVITPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9E559 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGSRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. NS26 TaxID=2293980 RepID=UPI000F03535B --------LSALEARHGGRIGFRLQG--PSGDV-GWRAEERFLYCSTFKLFLAAATLNRVD -RGEERLDRAVPITAEDITPHAPATEPAVGSTLTIETLCQAAVEVSDNPAANILIRELSGL -DAWRGWYRSIGDETTRVDRLETELNT--PDGDKDTTTPAQVVRNLQRLFVGGGVG-AHRD -LLTQWLTDTPTGAGRIKAGVPAGWTVAHKTGTGE-GPTGDIGLIWNADGGLMLVAAYYDA -PEATPEQRDAVIADAMRA----- ->[subseq from] class A beta-lactamase n=1 Tax=Citromicrobium sp. JLT1363 TaxID=517722 RepID=UPI000225DF01 ---RARAQLVDIEKRSGGRLGVALIDPAGAVLL-SHRGEERFAMCSTFKTLLAGMVLSGVN ---GLEPEDRLIIDPAAVEGHAPFTRSRFEEGMTVGDAAKNIVTVSDNGAANLLLDEVGGP -RGLTEWIRALGDDVTRLDRRELALNENAAGDPRDTTSPLAFGETYRRVLSDDVLDAADRD -QLARWLVASETGLNRLRAGIPGDWSVGDKTGYCAAVEINDVAIFDPAGGGWYTLVFFLDR -PREAGAFADALGAEVGAIAAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. USDA 6670 TaxID=936134 RepID=UPI00040377CA ---SLRAELAALASAHPGRVGICVQD-ETSRPI-CVNGEQRFSLQSVMKLVVAAAVMQAVD -EGRIALGDRFTIRREDLSVIQPIADIVAIKGTNVRGLVRRSVVESDSAATDVLISHLGGT -KAVQAFLDSAGLRDIRIDRTERELQTTYLTDPRDTATPRDMVGFLHRLATGELLSVSSSA -YLLEVMNGTVTFPDRLRAGVPSGWMIGHKTGTSQNGVTNDVGILTAPDSSHIAVAAFVAE -SRAGKDERAAMIAAAARAITAAy ->[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. JBTF-M21 TaxID=2584124 RepID=A0A547PCK1_9SPHN ----LTAKLRIAEAAANGMLGAEIYDTATGYCV-GLNRDRRFGHCSSFKLSLAAMVLARNA -AGQDSLDRRVTWTRDALMSVSPFTTERLGEGATLLELAEAVQKFSDNAAANILLREVGGP -QAMTGFWRSIGDETSRLDRMEPALNNVPITEVRDTTTPSAMARTVAKIAFGDVLPASEQS -MLRQWMTDTSTGMRRVRAGLPDEWRSGDKTGTSIGSLYVDIGFVEPEKHPPITFATYFRA -RETHDPTSETALARVGEIIAD-- ->[subseq from] Beta-lactamase CTX-M (Fragment) n=1 Tax=Escherichia fergusonii TaxID=564 RepID=A0A679G483_ESCFE --------------------------------------------------MAAAAVLKKSX -XEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTXNDI------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium sp. 52 TaxID=2035213 RepID=A0A2G6UNF4_9FLAO --qQLRNELQEVISTKKATFGISMKGIEDKDTL-SINGTMKMPMMSVFKFHIALAVLDQVD -KGKLQLNQKFFIKKEELHPWSPIKDEFPEGNLTLDQLLRYTVSHSDNNGCDLLLNILGGT -QTVQKFINKIGIKDFTIKVNEHEMTGE--NLYANTTTPIATTELLEKFYRGKVLKKVTTK -YLYKIMVETSRGITWMKAGLPEGTELAHRTGISGRAAMNDIGIVKLPNGKHFILSIYLKN -ISEERVATEKIIADITKAVWEYy ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A0M2NW81_STACC ----AAKSFDQIEQDNDTIVGVYGINTANGKVI-QHRSDERFAFASTYKAISSGILLQNTS ---TSELNKKITISKDDIVAYSPATEKYVGKQMTLRALIKASILQSDNTANNKIIEEIGGI -KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKRAATTLNHLLASENMSRSNLE -LLKHTMIHNETGDTLIKAGASKDDVVGDKSGQGTYASRNDLAFVYPENQKPIILAIYTKK -TDKDAKPDDKVIQTAAETAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D1C253A ----AAKSFDQIEQDNDTIVGVYGINTSNGKVI-QHRSDERFAFASTYKAISSGILLQNTP ---TSELNKKIAISKDDIVAYSPVTEKYVGKQMTLRALIKASMLQSDNTANNKIIEEIGGI -KGFQQALKQRGDNISNPQRLEPDLNLYDPQSTADTTTPKMAATTLNHLLASENMSRPNLE -LLKHTMIHNETGDTLIKAGASKDDVVGDKSGQGTYGSRNDLAFVYPENQKPIILAIYTKK -TDKDAKPDDKVIQTAAEKAIK-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Mucilaginibacter ginsenosidivorax TaxID=862126 RepID=A0A5B8W8J4_9SPHI ----LKAKIDEIAKDAKGTVGVSVLNLETGDTL-NYNGYLHQPMQSVMKFPIAITVLHEID -EGKFTLDQQLRLDKSDLFKYSPLQDKYPAANVSIRELLSYMVSLSDNVACDKLLKILGGT -DVVDTYIHHIGIKNFSIKASEYQMAQAWDVQFSDWVMASELTHLLNVAFKPNFLSTASHA -YLWKIMQETSTGPNQIKGLLPVGTIVYHKTGRSGTNATNDTGIITLPNGNHLAIAILVTN -SPVDLKTRESVIARIAKAAYD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A413E128_BACSE --qTLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REKIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYYNWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEKNAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=2 Tax=Francisella novicida TaxID=264 RepID=A0Q6U4_FRATN ----LNDSFKSLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPITQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL -QSLDKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGTNRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI000158B0AB ----LNDSFKSLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPITQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDNPAANILVRELGGL -QSLDKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGTNRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter epoxidivorans TaxID=361183 RepID=A0A0M3T9N4_9SPHN ----INAKLRIIEAASGGTLGVAMYKTLTGATA-GLNRFERFGHCSSFKLSLAAMLLSKDA -SGAIDAEELVRWTKDDLLSHAPFTTERLGQGATLRELARAAQVLSDNTATNLLLQRLGGP -EGMTAFWREIGDVSSRLDRMEPELNNVPAGEVRDTTTPDSMVRTVARLLFGNVLDRDNRA -TLLKWTVDTATGLQRVRAGLPSDWSAGDKTGTSHQPLYVDIGWVEPAGHPPTCFAVYHHT -KDETTTRANLVMQQVGEVIAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00059B05C6 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium oncorhynchi TaxID=741074 RepID=A0A316X1Z5_9FLAO ---ELKKIIESIIANKKADVGVSIMEVPQKEVV-QINGNKFYPMLSTVKFHIALAILHKVE -KGELSLQQKIYIKKDELLEWSPFQKEHPEGNLTLEETMKWMVSYSDNNLTDILLRLIGGP -EPVQKFINS---KNFVIKNNEEDMHKDWDSQFINTITPNEATRLLEKFYNGKLLNKEHTK -WLYTAMLNNASGAKRLKAHLPKSIKIAHRTGTSFTGAINDFGIIELSDKKRIYIAVFVHD -TYEKFENAEAIIADISKATYDYy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=A0A2X2V9C5_9FLAO --qDLRSKINTIISTKNTTVGISLKGIEDKDTL-SINGNKEMPMLSVFKFHIALAVLNQVD -KGKLKLDQKFFIKKEELLPWSPIREEYPEGNLTLDQLLRYTVSHSDNNGCDILIKIGGGA -PVVQKFINQQGIKDFTIRLNEQQMNTF-ESYFVNTSTPLATTDLLEKFYKGKVLKKETTK -YLYQIMVETSRGLTWMKAGFPAGTELAHRTGISGRAAMNDVGIVKLPNGKHFILSVYLKN -IHEEMKDTEKIIADIGNAVWEYy ->[subseq from] Beta-lactamase n=1 Tax=Francisella salina TaxID=573569 RepID=F8G6Z3_FRAST ---TIDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QHKGFLDKQILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -ENLNKLVAKLGDKDTIIKNDEPEINRTKLDSDINKTTPKAITQDIYNLAFGNILDKKHRE -IFIRYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQDKQPFALSVLYTN -PSVKAPSNEKIIQQASKLIAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Porphyrobacter sp. AAP60 TaxID=1523423 RepID=A0A0N1AZG7_9SPHN ---RLAAELRLIEAAGNGTLGVEIYDTASGMAV-GINRDRRFGHASSFKLSLAALLLQRHA -AGAINADKQVMWTEADMIAHAPFTRERIGSGASLRELARATQITSDNPAANILLKELGGP -AALTAFWRSIGDEASRLDRYEPEMNLVPTAEFRDTTTPAAMARTVAKLIYGDVLPEAERA -ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPLTFACYFRA -RQTEA------------------ ->[subseq from] Beta-lactamase n=2 Tax=Chryseobacterium joostei TaxID=112234 RepID=A0A1N7JBJ2_9FLAO ---ELKKIIESIIVNKKADVGVSIMEIPKKEVV-QINGNKFYPMLSTVKFHIALAILHKVE -KGELSLQQKIYIKKEELLEWSPFQKEHPEGNLTLEETMKWMVSYSDNNLTDILLRLIGGP -EPVQKFINS---KNFVIKNNEEDMHKDWDSQFINTITPNEANRLLEKFYNGKLLNKEHTK -WLYTAMLNNASGAKRLKAHLPKGVKIAHRTGTSFTGAINDFGIIELSDKKRIYIAVFVHD -TYEKFENAEAIIADISKATYDYy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=A0A0G3X957_9SPHN ----FERRIAQAADGSDGRIGVAVLDLATGQEF-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWSLSSEFPLLIPVRSERFSSAKARRGKHLPASELIELMITRSSNPATDALLAAVGGP -AAVNDWMRRAGITDFQLTRDIATLVRASAIDLRDSATPRAMTRLLAGLYQGEWLSPTSRR -VIIGAMERCRTGTRRIPALLPAGATVAHKTGSLNN-TSSDIGIINTPDGRAFAVAIYVTG -QG-TRLAREGRIAQIARAAYAGy ->[subseq from] Beta-lactamase n=2 Tax=Niabella ginsenosidivorans TaxID=1176587 RepID=A0A1A9HXV3_9BACT --nTLQTQFEHISNDIKGHLGISALLIETGESI-QFNGNKKFPMQSVYKFPIAMAMLNQID -AGKFSLEDTIHIDKSQYIPHSPIRDKFPKGALTIKDIIRYNIEESDGTACDVLLRLLGGT -DKAQQHIHEWGVTAIAIATTEMVQVANDTIQYQNWATPEAMNKLLQLFFEGRCLSRNSRE -LLLQYMSISEWFDRRIKGLLPPGTKVAHKTGTAGTRATNDVGIITLPDGRHLAITVFIAD -SYDSQKDREMAIARVSRAAFDYw ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SHI8_9BACT --qTLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REKIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYYNWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D0MVD9_9BACT --eKLRNEITEYLKGKDLKAGISFFSFSNGDTL-SINGDDFFPMQSVFKFHIGLAILNKAD -KGELNIEDKILIKKEDLKEWSPIREINPEGNLTIAELLSYSVSESDNNACDILIEIAGGT -EKIQKYFDDIGLKDFYIVANEYEMHQDWETQFRNKTTPKSSTEIIKKIYSDNLFSKKSFD -YLYKIMTETKTGQKRIKEQLPEGSIIGHKTGTSGKNAVNDIAFISLPNGFKYILSVYLTD -SKLDYPEAEKVMSDISKIISDYy ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. JM1 TaxID=1233950 RepID=A0A086ARE5_9FLAO ---DLSKELKQIISTKNATVGISIKNIEDKDTL-SINGHLDAPMMSVFKFHIALATLNLVD -KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGP -ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSTNAMNDVGIVKLPNGKHFIISIYLKN -ITEKREDTEKIIADLTKATWN-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SNN1_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRQEQLVKWSPLRERFPQGGFSLKELLRVTVKESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] class A beta-lactamase n=1 Tax=Sinorhizobium medicae TaxID=110321 RepID=UPI000462BC01 --nHLHTELAALASAHPGRVGICVQDPTSPPIC--VNGEQRFSLQSVMKLVVAAAVMRAVD -ERRVALSDRVTVRREDLSVIQPIADIVSERGTSLGDLLRRAVVESDSAATDMLISRLGGT -KAIQAFLGESGLHGIRIDRTERELQTAYLTDPRDTASPRGMVGFLHKLAAGQLLSASSTA -HLLEVMKKTVTFPDRLRAGVPSGWTIGHKTGTSRNGVTNDVGILTAPDGRHVAVAAFVAE -SRTGNEERAAMIAASARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000B6BE267 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKR------------ ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7EA47 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMAGFLHGLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AF77C7 ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SKR6_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHMRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKGLKEWGISGINVRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Class A beta-lactamase n=3 Tax=Cryobacterium TaxID=69578 RepID=A0A5F0EA32_9MICO ------RSVRQLESTSGVMIAVSAKNVRSGRQI-NHRATEPVPMCSLFKVLAVANLLRLRG -YEDQYWNTPISFTAADLVVNSPVATASTSMSMTPNQMADAALRFSDNTAGNLLLRELGGP -ATITEFAQALGAKRTRLERIEPELNEGLPGDVRDTTTAEDMVAIMKALLIDGDAGQLARS -RLQDLMLRNTTSGKRARAGLSEPFELADKTGAGDYGIVNDAGVLWQGQRQTIAMCILTRT -EIASAPNSNDVIADATRLIVS-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Flavobacteriaceae bacterium TaxID=1871037 RepID=A0A3B9DZ08_9FLAO --eSLRTEINQILSSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD -QNKLKLNQRFFIKKEDLLPWSPILEDYPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT -KTVQNFINKQGIKDFVIKVNEQEMQT-WDNLYLNTTSANATTKLLEKFYATKVLKKKSTT -YLYQLMVETSRGLTWMKAGLPENTELAHRTGISDTNAMNDIGIIKPINHQPIILSIYLKN -ITEERTETEKVITDITKAVWNYy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=A0A147EET6_9SPHN ----LEQQLASLAEASRGRIGVAALDLTSGRTV-DVLGDQRFPMASTSKIAIAATFLEGVD -QGRFSLSSEFPMMMPVPSRSTAVAPVRPGTYMSARSLIEAMITRSNNYATDALLKVVGGP -RAVNDWVRRAGVNDWHIDRDIATLVRATTIDTRDSATPLAMVRLLSQIYSGQMLSPASRD -VLLGAMGRCLTGKRRIPALLPSGTTVLHKTGSLNN-TSSDVGIIQTPDGRAYAIAIYVTG -QG-TRLARETRIASIASALYHGy ->[subseq from] Beta-lactamase n=1 Tax=Alistipes sp. AF17-16 TaxID=2292190 RepID=A0A396M2D6_9BACT ----LVRQIDSVLSRYRATVGVTVLS-NRDEIV-AANDSILFPLMSVFKFHIALAVLDRMD -RNRTRLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP -EAVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK -FLIRIMTETSTGQDKLKGLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD -SQEDDPTNASIIARISAIVYD-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium haifense TaxID=421525 RepID=A0A3N0WWI5_9FLAO --tELRQELENIIATKNATIGISIKNIETKDTL-NINGTLNTPLMSIFKFHIALATLNLVD -KGKLSLKQKIFIKKEELHEWSPIRDEYLNGNLTLDQLLRYTVSHSDNNGCDILLKLIGGT -ETVQKFINKQGIKDFTIKVNEREMQT-WESLYINTTTPLATTEILEKFYKGQVLKKKTTK -YLYQIMVDCSRGITWMKAGLPEGTELAHRTGISDRASMNDVGIFKLPNGNHIILSVYLKN -ITEEREVTEKIIADIAKATWNYy ->[subseq from] Beta-lactamase n=1 Tax=Oxalobacter formigenes OXCC13 TaxID=556269 RepID=C3X8Y4_OXAFO --qTLQEQVNAIVASHHAKIGIVIENADGSEQA-HYHSGDFFPMQSVFKFPIALAVLDKVD -KGELRFNQRIFLKKSDLRPWSPLREKYKNGNVSLKEILRTTMKDSDNNGCDILLKLAGGP -GAVTAYLREKGIKDMTVATTERTMHGDWNIQAKNRATPEATNRLLKLFYEKKLLKPDTQA -FLWAAMRDSMVSPERLRNGLPPKTPLIHKTGTSMGNTVNDIGIVVLPDGKPLFISVLVSH -GKEPKAKTEKMIARLSKTAWEHf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas guangdongensis TaxID=1141890 RepID=A0A285QYN7_9SPHN ----LQSRVAAVATSDRGEIGVSALDLTTGARL-AVKGDTRFPMASAVKVAIAATYLAGVD -EGRWQLSTMYPLDEAMRVRSDGITDTLPHAGLSGANLIELSLTVSDNTATDMLLKVVGGP -AAVTKWLQGQGISGQRVDRTIARLLIAFDADPRDSSTPDAMVALLARLHDGKALKPASTR -FLFDVLARTKTGAKRVKALLPAGTRWAHKTGTLP-GISNDVGVLTLPNGHKVAVAVLSHG -IA-DPVARDAKLAEIGRILFDGf ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI00068A3476 ---ALRKSFQALADKAPGLLGVAVRDAQTGQTV-AFNGDNRFPLQSVFKAALGAAVLAEID -AGKLRLDETITIRDIDLSPFSPVADAWPARTYTVAELLDRASGASDNTAADVLMKKIGGP -GALTAWLVLKNIKDFQIDRYERQLQPAYLADTRDTATPIAAITFLEALRAGQLLSRASTE -RLLAIMTATTTGKDQLKAAMSSSTTLAHKTGWARTDATNDIGVYTLKDGRQYAVAAFLSG -STASDAERDAIIADVGRIVLK-- ->[subseq from] Beta-lactamase class A n=2 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560G572_9PROT ---ALQARLDRLAQDFPGRGGIAVRDPATGTVA-EVKARERFPEQSVFKLTVAIALLDLVD -HGRMDLAQKVTLYPRDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP -AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLERLDKGELLSPASTR -RLLDILDHTTTQPNRLKAGLVAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS -VQGPRERADAFIASVARAVVESw ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A5Q3LRK9_RHIML --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIVDIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATRQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Class A beta-lactamase-related serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A437G4D1_RHIML --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIVDIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATRQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aureispira sp. CCB-QB1 TaxID=1313421 RepID=UPI000696B0D6 --eTLREKITTVIENKSATVGVAIQGSNSNDSM-SINGHQHLPMQSVFKYHLALAVLHQVD -QGKLRLNKKIVIRKKDIQAWSPLRKKYPNGAVSIAELLQYTVALSDNLGCDILFKLIGGT -SVVQSFLHKIGIKDIAIHHNEMVMQSEWEKQYDNWTTAKAANQVLELFFENNLLSAQSHR -FLLETLKGTKTGKKSIRGLLPQATIVAHKTGHSGTGALNDIGIVFLSDNSYFYISILVSD -SMEEDSVNQQIIAEIAKLTWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. OV715 TaxID=1500287 RepID=UPI00068B3A82 ---DLRQELKQIISTKNATVGISIKSIEDKDTL-SINGHLNAPMMSVFKFHIALATLNLVD -KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNITIDQLLRYTVSHSDNNGCDILLKLIGGP -ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSTNAMNDVGIVKLPNGKHFIISIYLKN -ITEKREDTEKIIADLTKATWN-- ->[subseq from] Serine hydrolase n=1 Tax=Nitrospirillum amazonense CBAmc TaxID=1441467 RepID=A0A248JQ79_9PROT ---ALQARLDRLAHDFPGQAGIAVRDGVTGAEM-GVKARERFPEQSVFKLTVAIALLDLVD -HGRMDLAQKVTLYPKDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP -AAVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLDRLDKGELLSPASTR -RLLDILDHTTTQPNRLKAGLAAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS -VQGPRERADAFIASVARAVVESw ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. (strain PM2-P1-29) TaxID=403776 RepID=A0A077XS50_SPHSM ----LQQYINQIITGKNALVSVAISGISQNDTV-GVQASQRLPMQSVFKFPLAIVMLTEID -KGNFTLDQKIEITKRDLTPWSPIRDKYPDGVLTLREILEYTITLSDNIGCDVMLKLLGGP -QKVEQYFAKQGFKNISIKINEKTMQSNWDKQFLNWCTPQEMNNILKIFYVNNLLSMSMYD -FLWSTMKSTNTGLNQIKGQLPAGTVVAHKTGSSGTAALNDVGIVSLPNGEYFVISIFVTN -SKESKETNERMISDIAKVTWDYf ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2L1J137_ECOLX ------------------------------------------------------------- ------------------------------GTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAAR------ ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. 36-9 TaxID=1895905 RepID=A0A1Q3ZAF4_9FLAO --nDLRKELNQIISTKNATVGISIKGIEDKDTL-SINGNMAMPMMSVFKFHIALTVLNEVD -KGKFKLNQKFFIKKEDLHPWSPIREDFPNGNLTLDQILRNTVSHSDNNGCDFLLKILGGT -DTVQRFINKQGIKDFTIKVNEQQMS-VWENLYLNTTTPLATTLLLEKFYNGKVLKKETTK -YLYQIMVETSRGITWMKAGLPKGTELAHRTGISDRAAMNDVGIVKLPNGKHFILSVYLEN -ITEEREATEKIIADIAKVTWSYy ->[subseq from] CTX-M-90 extended-spectrum beta-lactamase (Fragment) n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T1C031_9ZZZZ ---ALHAQFARIESQTGGRLGVAMLDTHNRIAA-GYRANQRFPVCSTWKLLAVAALLRQVD -EGHENLDRRIRFRASELVVYSPVTKDRVDATMSLRELCAAALVWSDNSAGNLLLAALGGP -SAITRFARAIGDPVTRLDRTEPALNEATPGDARDTTSPRAMLGDLDTLLLGNALTPPSRA -RLNAWLAASQTGAR---------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter zhengii TaxID=2307003 RepID=A0A418NTD7_9SPHN ----LERRIAQVADGSDGRIGVAAIDLATGEQV-SVLGDQRFPMASTSKIAIAATFLEGVD -QGRWSLTSEFPLLWAVRSQSTRVAPVREGEYMAAHQLIDLMITRSSNPATDALLAAVGGP -AAVNDWARRAGLNDFSLDRDIATLVRTYHIDLRDSATPETMARLLAGIYQGEWLSAESRD -VILDAMERCRTGRNRIRGMMPEGVSVAHKTGTLNR-MAGDIGIIEMPDGRAIALAIYVTG -QSASRRLRDSRIASIARALYDG- ->[subseq from] class A beta-lactamase n=1 Tax=Chitinophaga vietnamensis TaxID=2593957 RepID=UPI001178A659 --qSLQARLQEVAATIKGKTGVYAEVLETGDTA-SLHATTHYPMQSVYKFPIALAILQEVD -KGRLRLDQPVQIRKSVLTLHSPIRDSFPEGTMPLREVLRYNTCESDGTACDVLLGLLGGT -RNAEKAIHALGVRDIAIATTEKVQMEDELVQYRNWCTPAAMAQLLRIFYTKNILSPASKA -LLIKDMTETPVGLKRLKGELPPGTTVVHKTGTSNTRATNDVGIITLPNGKHLAIAVFVSD -AYGSTAEREGIIAQMARLCFDAf ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LUI7_ECOLX ------------------------------------------------------------E -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTQPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIW--------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=UPI001419FFA5 ---RLQQTLARLADEAPGTLGITVLDLGAHTRT-RINADRAYPMMSVFKAPVAAAILAQID -EGRLRPDQEVTIDSGDVLGGSPSIGAHFKGKFTVDRLLEAAVSESDNTAVDALIRLAGGP -QVVTAYLRKHGIDGMRIDLGEAGIVDAYMADPRNRTTPDAAADFLEKLWKGELLSATSTK -RLLALMYGQTV-PNRMRAGLPAGVRFADKCGTSYTAAFNDIGIVTWPDGRTVIVAAFLTG -SQTDAKDRNALFAEIGRAVT--- ->[subseq from] Uncharacterized protein n=1 Tax=Bosea vaviloviae TaxID=1526658 RepID=A0A0N0MCD3_9BRAD --aKLDKEIAAIERQSQGRLGVALLDLRDRKTW-SHRGTESFPMQSVFKWPLAIAALQAVE -AGKLQLDQPITIRRSEFSLHSPLAKAFKGDSYPLRELIALAAGESDNTAADILMREIGGP -KVVSAMLRDGGISGISVDRYERQFQPAALKDKRDSATPEASVLFVEAQAKGNWLRDPAHN -ALIDIVTQTKSGPDRIRAGLPQGAGFAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLVG -STADAKEREAAHAAVAKAAVS-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sp. GA093 TaxID=2683249 RepID=UPI001365C1E3 ----LRNKIEQILSKKNAVVGVSIIGNNGKDTL-SLNGERRFPMQSVFKFHIALAVLSEID -KGKLSIDQKIEIGKDELLPWSPLRDENPNGGFTIERLIQYSVSHSDNTACDVLIRLIGTP -KTVEEYIKKSGVNDIQITFNEEEMQKKLENMFQNWTTPKAASQTLKLFYENKLLSKNSYD -FFWKTNIETTTALSRIRGLLPKEIIVAHKSGSSGTNAVNNIGIVFLPDGEYFYISVFVTK -SHENAKTNDRIIADIAKATYDFy ->[subseq from] Uncharacterized protein n=1 Tax=Luteimonas sp. FCS-9 TaxID=1547516 RepID=A0A0H1ALI5_9GAMM ------GDIGSLEAASGGRLGLCLLGPDRRRVV-AHRARESFPTASTIKFALSAAVLAQAD -AGALSLDDRIAVRAQDIRSGASVTGRHVGKDMTVRDLCRGSMVWSDNPAVGLLLPLVGGA -PGLQAFLRRHGDADTRTDGIAEGA---------STTSPDTMARNLARFVLDDALSRPSRL -QLADWLIENRTGDARIRAGMPAGWRVGDKTGGMA-GVSNDIAVLWPPGGVPWLLALYLQG -SPLQAGARDAVLRRATELVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Demequina aurantiaca TaxID=676200 RepID=UPI0007810840 --------------EYDAEVSVSVVEPGGAEPF-GFHHTERRGFASTIKAVIAAAAFAQLS ---ADERDETVTWTREKVSLYSPVTSEHFDDGLTLSELIEASVRYSDNTATNLVLQRIGGP -DVVNEALAALGDDVTNLADEEPALNYISEASAANTTTSLAIAQTLQNIVDSDYLEAEDRT -LLLDLMSGNATGDSLIRAGAPAGWEIADKSGGAG-AIRNDIAVAYPPQGDPVIITILTTR -TDRSKPYDDKLVEDAASAVFD-- ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0012E15568 ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Empedobacter brevis TaxID=247 RepID=A0A5P2G8U4_9FLAO --eRLRTEINQIISSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALTVLHEVD -QNKLQLDQKFFIKKKDLLPWSPILDDFPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT -KIVQNFIHKQGVKDFVIKVNEQEMQK-WDNLYINTTSANATAKLLEKFYTNKVLKKNSTT -YLYQLMVETSRGSTWMKAGLPANTELAHRTGISDTNAMNDIGIIKLVDGKRIILSIYLKN -ITEERAETEKVMADITKAVWNYy ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AF8AD3 ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AED421 ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGLSGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127SSQ5_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYTGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A414PZW1_BACSE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina pacifica TaxID=1296415 RepID=UPI00046ECEDA ----LRNEIEKIISDKNAVVGVSIIGNNGKDTL-SVNGDKQFPMQSVFKFHIALAVLSEID -KGALSLDQIVKIDKDELWKWSPLRDENPNGGFTIEKLIQYTISQSDNTACDVLIRLIGTP -KTVEGYMKKSGIEDIQITFDEKEMQEKWENMFQNWTTPNAANKTLKIFFENNLLSKRSYD -FFWKTNIETTTALGRIRGQLPKEVVVAHKSGSSGTNAVNNIGIVFLPDGEYFYISVFVTN -SHENNKMNDKIIADIAKATYDFy ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E2ZXD4_9GAMM ---TLDDSFKNLEDKYHGKLGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -PSVKAPSNEKIIQQASKLTAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. Gsoil 351 TaxID=2675225 RepID=UPI0012B4AFA2 --rALETQLRAIVANSGGRIGIYAADVDGPRAV-TINANQAFPMASTVKVAIAAAYLQGVD -DGRLRLDTAYPLRIGTGQTGADGRVTREGMSLSAQSLIELMITKSDNQATDAILSAVGGP -AEVNRWLLGAGISGLRVDRDIATLLRVLGLDKRDTVTPAAMVRLLGALHRGEVLSPQSRA -VLLGAMSRCKTGKTRIPALLPEGTLIAHKTGTLW-AQTSDVGIIRLPDGRNVALAVYVTG -QS-SHAAQAQTIAQVARTVYDSf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PhB165 TaxID=2485105 RepID=A0A4R1UPS3_9SPHN ---DFERRLASVAEGSQGRIGVAAVDLSTGRSV-DVLGSQRFPMASTAKVAIAATFLEGVD -KGKWSLSSEYPLMIPVASASSSVAPVRPGAYMSARQLLELMITRSNNYATDALLKVVGGP -SAVNAWVRRAGIDDWHLDHDIATMVRAKVVDKRDSATPLAMVQLLTGIYQGKWLTPESRD -VLMGAMGRCLTGRNRIRAGLPSGVNVSHKTGSLSN-TSSDVGIIETADGRAYAVAIYVTG -QG-NRPAREARIASITRTIYEGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=UPI000E4BACE4 --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REKIPLKHIVHVKASQLQPYSPMRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium 2SD TaxID=2502200 RepID=UPI0010F60500 ---KLDAGIKTIEQSTKGRIGVGLIDLKDRKSW-SYRGTEPFPLQSVFKLPLAIGVLQAVE -AGKFKLDQPITVTRNDLSLHSPLAKAFKGERYPLRELLTLSTGQSDNTAADLLLRLIGGP -QALTALLKDGGVTGISVDRYERVFQPATLADKRDAASPEASIAFLEGLAKGNWLREPANA -ALLDIMLEAKTGPNRIKAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -AKVGEKEREAAHAAVAKLAVE-- ->[subseq from] Beta-lactamase n=2 Tax=Dyella japonica TaxID=231455 RepID=A0A0G9H3W8_9GAMM ----LQHALDALAQRAPGTLGVAVLDLKSGAAA-GVDADRAFPMMSVFKAPVAAAVLSRID -DGSLSLQQSVTVTRDQVMGGSPSLGAHFHGEFTVEQLLKAAVTESDNTAVNALIRVAGGP -GVVTTYLHAHGIDGMRVDVDEAGIAQAFLADPRNRSTPDAAIAFLRKLVQGELLSPVSTQ -RLLALMEAQTI-PNRLRAGLPAGLRFADKTGTSGTAAFNDIGIIRWPDGHTVLVAAFLMD -SPASDPQRAALFADMARTVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E3ZWL8_9BACT ----LSQELMRLSDMSGGKVGICATHIETGKTI-TQNGKEGFPMASSYKVAIATQLLTRVD -SGSLTLAQLVPITKSDFHPGSGMLS-----SLSVRSLLELMLLISDNSATDICLRLAGGP -AAVNACMKRIGVEGLRVDRPTAWLIAAFENDPRDTSTPEAMTLLLTKLYTQPVLKPASQA -LVLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGNGHVAISVFVKA -SHKDGPVRERTIAEVTRTIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD71192 ---RLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIVDIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATRQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase class A n=1 Tax=Altererythrobacter ishigakiensis TaxID=476157 RepID=A0A562UU68_9SPHN ---RLAAKLNIIEAASGGTLGVAFLNTATGAIM-GHNLGTRFGHCSSFKLSLAALTLWRDQ -QSIDDADRLVRWSEDELVAYSPFTAPRTEQGATLSALAEATQKTSDNSAANVLLREFGGP -EALTRFWRLIGDTGSRLDRIEPALNHVPKGELRDTTTPAAMVRTVAALCFGEVLKDANRQ -TLRQWVVDTKTGARRVRAGLPEGWTAGDKTGTSFASLYVDIGFATPPARAPLTFATYYRA -PNIQDPRSEQVLAQVGEVLAE-- ->[subseq from] Beta-lactamase n=1 Tax=Spirochaetes bacterium ADurb.Bin215 TaxID=1852910 RepID=A0A1V5WJB8_9SPIR --dALREQIESITAKSNARTGVALYDPVKRDTV-ALNGTSQFPMHSVMKFPVALAVLSEID -KGNLSLKQRVTITSEDLEPWSPIKAAYPDGTLTIEQILKYTVADSDNIGCDILLRLIGGT -MSVQKFLDTHGFTGISIGATEQEMHDDPDKQYLNSSSPGAMNKLLSAAYTGALLSRESHE -WIWKTLQEATTGGTRIKGLLPKTAIVAHKTGTSGIAAVNDVGVLILPDGNVLYLSVFVAD -SRETPAETEKIIAEIAKAVWDHy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A3E4KXU1_9BACE --kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMKIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEELMHRDVATQYQNWSTPEAVVRLLNIADKQTLFAAEYKD -FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDQENAAIIARISKIVYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD967A1 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRCIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI00130E7BB2 --aKLDKEIAVIERQSRGRLGVALLDLRDRKTW-SHRGAESFPMQSVFKWPLAIAALQAVE -AGKLKLDQPITIKRSEFSLNSPLAKAFKGESYPLRELIALAAGESDNTAADILMREIGGP -KAVTAMLKGGGISGISVDRYERQFQPAALKDKRDSATPEASVLFVEAQAKGNWLRDPAHS -ALIKIVTETKSGPDRIRAGLPEGARLAHKTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG -SSADAKQREATHAAVAKAAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseobacterium oleae TaxID=491207 RepID=A0A1I4VXY8_9FLAO ---DLRKELKQIISTKNATVGISIKSIEDKDTL-NINGHLNAPMMSVFKFHIALATLNLVD -KGKISLAQKVFIKKEDLQQWSPIKDEYPNGNLTIDQLLRYTVSHSDNNGCDILLKLIGGP -ETVQKFINRQGIKDFVIKVNEEEMR-IWKNLYINTTTPLATTDLLEKFYKGKVLKKATTQ -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISSRAAMNDVGIVKLPNGKHFIISIYLKN -ITEKREDTEKIIADLTKATWN-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000488BF2E --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHGLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. AF48-12 TaxID=2291998 RepID=UPI000E511D91 ---TLVRQIDSVLSRYRATVGVAVLS-DRDEIV-AANDSILFPLMSVFKFHTALAVLDRMD -KNRTPLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP -EAVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK -FLIRIMTETSTGQDKLKSLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD -SQEDDPTNASIIARISAIVYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD98AB5 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHGLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. AD56 TaxID=1528744 RepID=A0A2N7QPC5_9GAMM --eTLQHSLEALAQRAPGVLGIAVLDLNSGASA-RVNADQAFPMMSVFKAPVAAAVLSHVD -SGTLSLQQPVTITRDQVMGGSAIPANFRGERFTVEQLLKAAVSESDNTAVNALIRTLGGP -SVVTDYLRAHGIDGMRIDIDEAIVSQAFLADPRNRSTPDAAIVFLHKLVGRELLSPASTQ -RLLALMEAQTI-PNRLRAGLPQGVRLADKTGSSGRAAYNDIGIVTWPDGHRVLVAAFLLD -SPGSDKARDALYADIARSVV--- ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. 9U TaxID=2653158 RepID=A0A653J5T8_9SPHN ----FEQQLAALAEGSQGRIGVAALDLGTGRTV-DVLGDQRFPMASTSKIAIAATFLEGVD -QGRFSLSSEYPMMMPLPSKSSSVAPVRPGTYMSARSLIEAMITRSNNYATDALLKVVGGP -RAVNDWVRRAGVTDWHIDRDIATLVRATTIDSRDSATPLAMVRLLSQIYNGQMLSGSSRD -VLLGAMGRCVTGKRRIPALLPMGTTVLHKTGSLAN-TSSDVGIIRAPDGRAYAVAIYVTG -QG-NRLNRESRIASIARALFHGy ->[subseq from] Beta-lactamase class A n=1 Tax=Porphyrobacter sanguineus TaxID=198312 RepID=A0A1M7SSC2_9SPHN ---RLAAQLRLIEAQGNGTLGVELFDTATGLSV-GINRDRRFGHASSFKLSLAALLLERDA -AGAIDGDKRVMWDEADMLQHAPFTRDRMAKGATLRELARATQVTSDNPAANILLRELGGP -AALTAFWRSIGDEISRVDRTEPEMNNVPTSEFRDTTTPAAMARTVAKIIYGDVLPEAARA -ELKGWMIATETGLRRVRAGLPEGWVAGDKTGTSGY-NYIDIGFAEGPKGPPITFACYFRA -RQSELASGEMTLARVGA------ ->[subseq from] Beta-lactamase n=1 Tax=Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8) TaxID=682795 RepID=G8P1Y7_GRAMM ----LHQQLATIAKDAHGQVFVACSLPGVALDC-NLNPHGHPPMQSTFKLPLAVALLQQVE -RGKLKLDQPIRFLPSDRYPYSPLQDAHPEANVPLHDLLQLSVGESDNTATDILLRLIGGP -QAVQESMNKLALPAIHVRDSERGLHDDFQAQYRNDAEPAAMVTLLRMLADHSPLSAEHTA -LLNRWMTESSTGPHRIKGLLPAGTPVAHKTGTSGEHATNDVGLITLPNGQRLALAIFVTD -AHADETTRDAVIARIAKAIYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000EFB45BC --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase class A n=2 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560F4Z7_9PROT ---ALQARLQRLTHDFPGRAGIAVRDGVTGAEV-GVKARERFPEQSVFKLTVAIALLDLVD -HGRMDLAQKVTLYPQDRSVWQPLAKNITPAGTTLGDLMARMVADSDNVAADTVLRLVGGP -AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLDRLDKGELLSPASTR -RLLDILDHTTTQPNRLKAGLAAGWAVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS -VQGPRERADAFIAGVARAVVESw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012970065 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAGFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. B1 TaxID=1938756 RepID=A0A1W2BKZ2_9SPHN --qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE -KGAYRLDQQFPMMVRVAERGAPSPEARAGTVMTAQSLMELMITRSHNEATDGLITAVGGV -QNVNRWLTRNGITGQRLDHTMATLVRARVIDTRTSSTPRAMVALLAAIDRGNVMSPESRA -VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLS-GVTDDVGIVRLPDGRHLALVFFVTG -PEG-HAAHAGLIARMTRAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. ABRDHK2 TaxID=2571749 RepID=A0A4D7DC53_9SPHN ----IQQQIAAIASQSRGRIGVAAMDLDGGGQI-FLNGDMPFPMASTAKIAVAATFLEGVE -QGRFRLDQRFPMMLSVPERRSPIAPVRAGPVMTAQELMELMITRSNNQATDGLIAAIGGI -SPVNQWLTRKGIVGQRLDHTMATLVRATVIDTRTSSTPRAMLALLAAIDRGGALNPESRA -VLLDTMTRTSTGRNRIRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAMVVFVAG -PEG-HAVQSTLIAQVARVLYDGy ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=C7F8X1_ECOLX -------------------------------------------CGSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTG----------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides salyersiae TaxID=291644 RepID=UPI0003270634 ----LKADFDKLLQDKQATVGVAVVS-DGRKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD -RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV -EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE -FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD -SKEDDKTNAALIAAISQKVYEYy ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces albus TaxID=1888 RepID=A0A0B5EVB2_STRA4 ------------------------------------------------------------- ---ARALAELVRYSRADLLPDSPVTGEHLGQGLSLAALCEAAVRHGDRTAGNLLLRHLGGP -GALTRFARSVGDRVTRLDRWEPELNSAEPDRRTDTTTPYAIARTYAHLTVGDALGTADSC -LLTGWMRQHTAGPARFRTGLPAGWLLADTTGGGPYGTGHDVGIAWTPEGTPLLLACLTRG -SEPGEEPDEALLAETAALLA--- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. FSY-8 TaxID=1908523 RepID=UPI0013767E0C ------LQLARLANASMGRIGVAAVDLSTGKGV-SVMGDQPFPMASTSKIAIVATFLEGVD -QGRFRLTDRFPLMMPVPSASSVVAPVRPGSSLTAHELIELAITRSDNHATDALLAAVGGP -QAVTGWMKRAGLHGMRLDRDIATLVRARVIDPRDSATPQAMATLLAGIYQGQWLSNSSRD -VLLGAMSRCVTGRSRLRAQLPADAMVGHKTGTLNN-TSSDVGLIRASDGRMIAVAIYVTG -QG-GKPGRDSRIATIARAIYEGy ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter confluentis TaxID=1849021 RepID=UPI00136CE9B3 ----LEQRIARLAVGDKGRIGVAAVDLTTGAEL-SVLGDQRFPMASTSKIAIAATFLEGVE -QGRWSLSSEFPLLVPVRSAYSTRVAPVSKGQLAASELIELMITRSSNSATDALLAAVGGP -KAVNDWTRRAGIREFRLDRDIATLVRAAHIDLRDSASPKAMIDLLSGLYQGKFLNSSSRR -VILGAMERCRTGKRRIPALLPASAQVAHKTGSLNN-TSSDIGIIQTPDGRAIAVAIYVTG -QG-SRLAREDRIAQIARAVYDGy ->[subseq from] Beta-lactamase n=1 Tax=Aequorivita lipolytica TaxID=153267 RepID=A0A5C6YNZ0_9FLAO ----LRNQIEQIIAAKNAAVGVSLFGLETGDTL-SINGNKNYPMLSVFKFHIALTVLNKVD -KGELSLNQKLFIKKSELLEWSPFRDKFPDGNITLKEAIQWTVKNSDNNICDILIRLIGGV -KTIDSFINN---PDFIIVNNEEDMHQNWEAQFLNTTTPNNATHLLKKLFQTQILTKSSTK -FLYKTMLETSVGQNRIKGKLPKNTEVAHRTGSSFTGAINDIGIVKLPNGQHFAISVFVHN -TTEKFKDGEEIIADIAKATWDYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6W8U9_9SPHN ---RLEAEFARFAAMTDGTVGIAVRRLNDAPML-VLNGNTLFPMASTYKVAVAGTILSQVD -RGALTLDTMLPVDHRMLVSGIADTMPHPGLAMSVYNLMDLMLTRSDNSATDVLVNQAGGP -AAITAWLRSVGVRDQRVDDNTAQLLYAFAEDPRDTSTPEAMIDLLAKIAQGKALKPGTTQ -VMLEIMARCHTGEHRLKAMLPPGTPIAHKTGSLN-GLGNDVGIISLPDGTSFAIAVFVMK -DTKGKDARDRVMAEAARAAHDYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Acinetobacter baumannii TaxID=470 RepID=Q19RM1_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIMRRCS------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6WGN8_SPHSX ----LEAQFAFLAKQTDGIVGVAVQKVGSSEIM-TLNKGVTFPMASTFKVAVAARIFEKID -KGELTLDQIIPVDPKILVGGLAVMTPHDGISLSVHNLLELMITISDNTSTDVLVQLAGGP -AAVTDWLTRHGIKGQRIDADTAHLIYPFNADPRDTSTPEAMVQLLLLIESGKALSADSTK -ELLAIMGRCTTGEKRLKGLLPIGTVVAHKTGTLMS-VANDVGFITLPDGSRFAIAVFVKG -DTKGTETQDRVIAEMARTAYDYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina macrocephali TaxID=666563 RepID=UPI001268253A --eTLRQKIDSIINTKKAIVGVAINGIKVKDTL-SINGQRHFPMQSVFKFPIALTILSEID -KGNLSLNQKIDIKKSELLPWSPIRRKYPEGGLTIAEIIKYTVALSDNVGCDVLLKLLGEP -QVVENHFSSLGFKDFAVKINEETMQNNWDSQFLNWTIPKEANKILATFYENKLLSKKSYD -FIWNIMKGTKTGKNRLRGQLPKETIVAHKTGWSGTAAVNNIGIVFLPNGEYFTISVFVTE -SVEDFETNEKIISDISKAAWDYf ->[subseq from] Class A beta-lactamase n=2 Tax=Flavobacteriaceae bacterium CRH TaxID=1742859 RepID=A0A101CQQ2_9FLAO ------------IASKNATVGVSMKGIEEKDTL-SINGNLKAPMMSIFKFHIALTVLNQVD -RGILKLDQKIFIKKEDLHSWSPMREEFPDGNFTLDQLLRYTVSHSDNNGCDILLKFIGGP -KTVQKFINKQGIQDFVIKVNEQEMS-IWENLYLNTTTPEATTKLLEKFYKGEILKKSSTK -YLYQLMVETSRGKTWMKAGLPENTELAHRTGISGRAGMNDIGIVKLPNGKHFILAIFLKN -ITEEFEDTERIIADITKAVWEY- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium sp. 40-24 TaxID=1895843 RepID=A0A1Q4G7Y9_9SPHI --nSLRKELHQIIATKNATVCISMKGIGTKDTL-SINGHLNAPLMSVFKFHIALATLNLVD -QGKLSLSQKFFIKKEDLHAWSPIREEFPNGNLTLDQLLQYTVSHSDNNGCDILLDLIGGP -ETVQKFIHKQGIKDFTIKVNEQEMRT-WENLYVNTTTPLASTELLEKFYAGQVLKKNTTK -YLYQLMVECSRGLTWMKAGLPKGTELAHRTGISDRAAMNDVGIFKLPNGNHVVLSVYLKD -ITEEREVTEKIIADITKAIWNYy ->[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A1E4MAL2_9SPHN ----IQQQIAAIASQSRGRIGVAAMDLDGGGQI-FLNGDMPFPMASTAKIAVAATFLEGVE -QGRFRLDQRFPMMLSVAERRSPIAPVRAGPVMTAQELMELMITRSNNQATDGIIAAIGGI -APVNQWLTRKGIVGQRLDHTMATLVRATVIDTRTSSTPRAMLALLAAIDRGGALNPESRA -VLLDTMTRTSTGRNRIRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAMVVFVAG -PEG-HGPHSALIAQVARVLYDGy ->[subseq from] Beta-lactamase n=1 Tax=Algoriphagus lacus TaxID=2056311 RepID=A0A418PN94_9BACT ---ALRETIVEYLAEKNALVGVSIIGNDGKDTL-SINGERRFPMQSVFKFHIALAVLSEVD -KGNLSLDQEVLIKKEELLNWSPLRDENPEGGFTIKQLIQYTVSHSDNTACDLLIGLIGTP -KDVETYFKKNGIQDIEITFNEKEMQANWDNMFKNWTTPIAASETLALFYEDNLLSESSHE -FFWRTNVETSTGENRIKGKLPKGTIVAHKTGWSGTAAVNNIGIVFLPNGEYFIISVFVTE -SKESFEVNEMIIADIAKVTYDFy ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=A0A2U9Q5E4_PSEAI -------------------------------EI-LDRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPA-------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter marinus TaxID=538382 RepID=UPI001361AED4 ----FEQRIAIAADGSKGRIGVSVLDLATGQEF-SILGDQRFPMASTSKIAIAATFLEGVE -QGRWSLSSEFPLLFPLRSQSSPKAPVRRGKHLPASELIELMITRSSNPATDALLAVVGGP -EAVNDWMRRAGIEDFQLTRDIATLVRAAAIDLRDSATPRAMTKLLAGLYQGRWLSPSSRA -VIIGAMERCRTGKRRIPALLPAGATVAHKTGSLNN-TSSDIGIINTPDGRAFAVAIYVTG -QG-SRLARESRIAQIARAAYAGy ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. A27 TaxID=1755991 RepID=UPI001177C70B -hdRLQATLEQYARSAPGLLGIAVLDMRSSAEW-HVNGERPFPMMSVFKAPLAAAVLDLVD -KGRLPLDRRVTITRDQLRAESAIRTNFQGERFAVAELLRAAVSESDNTAADALMRAIGGP -SVVTAYLHAHGIDGMHVEMDEGQVAEAYLDDPRNRSTPVAAVDFLRKLVSGALLSPASTQ -QLLTLMRDQTS-PRRLRAGLPADVTFADKCGTSLTAAFNDIGIMTWPDGRRVIVAAFLMA -SAASRADRDKLFADLAKAVAQ-- ->[subseq from] class A beta-lactamase n=1 Tax=Olivibacter sp. XZL3 TaxID=1735116 RepID=UPI0010658C5F ----LQTQFEQIAKNTKGNVGVCALIIETGESI-SFNGDKAFPMQSVYKFPIAMAVLKKVD -EGELSLDKMIEVDQSEYIPHSPIRDNFPKGTLTIRDLLKYNIEESDGTACDVLLRLLGGT -KNAERYIHKLGIMDIAISTTEMVQVANDTIQYQNWATPKAMSQLLKTFYAAGDLSKNSSA -LLLGYMSVSSYFDRRIKGLLPQETAVAHKTGTAGTRATNDVGIITLPNDQHLAVSVFISD -SYDSQKERELTIAKISRAAFDYw ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000716E3BE ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRN------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A4Q5G8R5_BACSE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REKIPLKHIVHVKASQLQPYSPMRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFTLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0000F5914B ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase n=1 Tax=Francisella tularensis subsp. mediasiatica TaxID=135248 RepID=A0A4Q7HGT1_FRATU ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649UHG5_ECOLX ------------------------------------------------------------- -----------HYRQQDLVDYSPVSEKHLADGMTTGELCAAAITMNDNCAAYMLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEH- ->[subseq from] HGA-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0M0_9ZZZZ --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNKVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLQQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEEDAAIIAHISRIVYDE- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium fuchskuhlense TaxID=1117702 RepID=A0A124JVF0_9SPHN ---AIEQQVAAIVAQGRGRVGVAAVDLDGGGQI-MINGDMPFPMASTAKIAIAATYLAGVE -QGRLRLDQQFPMMVPVAESRGTVAAVRPGEVMTAQSLMELSITRSDNHATDGLIAAVGGI -GAVNTWLSRIGVSGQHLDHTMATLVRVTTIDTRTSSTPRAMAQLLTAIDRGGALSPESRA -VLLDTMTRTSTGRNRIRSGLPEGVVFAHKTGTLA-GVTDDVGIVRLPDGRHLAIAIFVTG -PEG-HTAHASMIAQIARVLYDGy ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A2N8HHV4_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKGTQR -LLWDMMTGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Beta-lactamase n=1 Tax=Flavobacterium kingsejongi TaxID=1678728 RepID=A0A2S1LS47_9FLAO --tKLEEQIIVLSAPFKAKIGVTALVLETEEILvSFHGGDRFPMQSVYKFPIAMAILNEVD -QGRLQLHQKIKVEPSEIIPVSPIREKYPQGALTLSELLRLNIVDSDGTACDVLLRIMGGT -AKVQHYLNSLGITGINIATTEMVQVSDDWIQYQNWSTPDAMTQLLYLFYSKKVLSTPSRL -LLLKWMEESIPGAKRLKGALPKNAIVAHKPGTSGTNATNDVGIITLPNGNHLAISVFVAD -TYVSREEREGLIAAIAKMAWDY- ->[subseq from] Beta-lactamase n=2 Tax=[Pseudomonas] mesoacidophila TaxID=265293 RepID=A0A2A4FM08_9BURK -hdRLQATLDRFARAAPGTLGIAVFDMHGSAEW-HVNGDRSFPMMSVFKAPLAAAVLDRVE -RGQLALNQRVTITRDQLRPESDIRDTFQGDRFSVDALLHAAVSKSDNTAADALLKVVGGP -GVVTAFLRAHGIDGMRVDMGESQVSEAYLSDSRNRSTPVAAADFLRKLSTGALLSATSTQ -YLMTLLREQTN-PRRLRTGLPAGVTLADKCGTSPTAAFNDIGVMTWPDGRRMIVAVFLTA -SPASRADRDRLFADLAKAVAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=G8FXI6_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Stenotrophomonas maltophilia TaxID=40324 RepID=Q3V775_STEMA -----ATDFAALEKACSGRLGVTLLDTGSGRRL-GHRQDERFPLCSTFKSVLAATVLKQAE -RDPALLDQRLPVRAQDILEHAPVTRRHVGKDLTVRDLCRATLITSDNTAANLLFAAIGGP -PAVTAFLRASGDTITRSDRLEPELNSFAIDDPRDTTTPAAIAATLQRLVLGDALKPASRQ -QLADWLIDNRN------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Bradyrhizobium japonicum TaxID=375 RepID=UPI0005779106 -------ELESYERETGGRIGVYAENLATGAKL-AWRADERFVMCSTFKASLAACVLARAD -RGEEQLAAVIPYGKADLLDYAPVAKQNLAAGMSVAEMCKAIVELSDNTCANLLLARIGGP -AALTAFWRSLGDTTSRLDHNEPELNRSPPGDPRDTTTPAAMAGNLKRLVVGEALSPASRT -QLTEWMV----------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=2 Tax=Motilimonas sp. PLHSC7-2 TaxID=2303987 RepID=A0A418YBJ2_9GAMM ----VLPQVKTLQGQVQGQISLAVMASDGAWLW-HYQGQTSVALMSTFKPFACAKLLNDFE -QGRVSKEHKVMVEADTLQAYSPVAKDWLNQAVSYQQACEATLRTSDNTAANIVLEGIGGP -QGLTGFFRDIGDNRSRLDDIEPKLNQVALGETNNTSHAIALVQSLQRLTFGRVLTTGSQE -QLLTWMKANQVSDNLLRASLPEGWRIADRSGAGKQGDRGIIAVVWPDNTQPVIMAIYIQH -AKADMAQLDQAIAAIGASLF--- ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. DHG54 TaxID=1920168 RepID=A0A370K6F0_9GAMM --rQLQRALDALVQRAPGVLGVAVLDLQSGASA-GVHADQAFPMMSVFKAPVAAAVLARVD -GGSLSLDQPVVIHQADVLSGSPSIGAHFHGEFTVGQLLTAAVSQSDNTAVDALIKVVGGP -EVVTAFLRAHGIAGMRVDQGEAGVSRAFLADPRNRSTPEAAVTFLHKLWKGELLSPASTQ -RLLNLMYAQTI-PNRLRAGLPANVRLADKSGTSWIAAYNDIGILSWPDGHVVIVAAFLSD -SPATPAARDALFAGLARDIA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SL22_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQGSDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI001296EC68 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPARLHAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Serine hydrolase n=1 Tax=Chryseobacterium bernardetii TaxID=1241978 RepID=A0A3G6TL63_9FLAO ---EFKKAIESILANKKADVGVSILTAGTKKEVtQINGNKLLPMLSTFKFPVALAVLHKVE -KGELSLQQKIYIKKEELLEYSPFREKYPEGNLSLEDCIQWMIVYSDNNLTDILLRLIGGP -DYVQNFINS---KDIVIKNDEEDMHKDWDSQFINTITPNEAIRLLEQFYNGKILNKEHTK -WLYTAMLNNATGTKRLKGKLPKDVKVAHRTGTSFTGAINDYGIIELSDKKRIYIAVFVHD -TYETFENSESIIADISKAAYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD7A3C9 --dRLRSELTVLANAHPGRVGICVREEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris CAG:120 TaxID=1263053 RepID=R6B270_9BACE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHDNEMHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Flavobacterium aquicola TaxID=1682742 RepID=A0A3E0EV58_9FLAO --nELRKQLKEIIASKNASIGVSIKNIEDKDTL-SINGNLNAPLMSVFKFHIGLTALNLVD -NGKLSLSQKIFIKKEDLHEWSPLRDEYPNGNLTLDQLLRYTVSHSDNNGCDILLELIGGT -KAVQKFINKQGIKDFVIKVNEKEMST-WENLYINTTTPLATTALLEKFYNGKVLKENSTK -YLYTLMAECSRGLSWMKAGLPVGTELAHRTGMSGRAAMNDVGIVKLPNGRHLIISIYLKN -ITETKENTEKILADITKLTWDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium hercynium TaxID=387094 RepID=A0A226H401_9FLAO --tELRKKIEHLISNKKLTAGISIKRIEDQDTL-SINGNLEAPMMSVFKFHIALTVLDLVD -NGRLKLDQSFFIKKEELLPWSPMREEFPEGNLTLDQLLRYTVSHSDNNGCDILLRQIGGT -ETVQKFINSQGIKDFTIKVNEEEMST-WENLYVNTTTPLATTTLLEKFYKGQVLKETSTK -YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNNIGIFKLPNGQHVILCIYLKN -ISISMKATEKLMADITKAVWKHy ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides stercoris TaxID=46506 RepID=B0NPP4_BACSE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNKVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLQQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPQKAYANWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEEDAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=1 Tax=Muricauda lutimaris TaxID=475082 RepID=A0A3A1NAT8_9FLAO --eTLRQKIDSITNTKDVIVGVAINGFKTNDTL-SINGQRHYPMQSVFKLPIALVILSEVD -KGNLSLDQKIDIKKSELLPWSPIREKYPEGALTIAEIIEYTVAMSDNVGCDVLLKLLGKP -QVVENYFSSLGFKDFAAKINEETMQSNWELQFLNWTTPIEANKILSTFYKNKLLSQDSYD -FIWNILKGTKVGKNRLKGQLPEETVVAHKTGWSGTAAVNNIGIVFMPNGEYFTISVFVTE -SKEDFKTNEKIISDISKVAWDYf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sediminis TaxID=1689985 RepID=UPI001328FED7 --nQLERKIALLANGEKGRIGVAAIDLATGAQV-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWSLSSEFPLLVPVRSASSRVAPVKRGAHLPASELVELMITRSSNPATDALLAVIGGP -KAVNDWTRRAGIREFQLDRDIATLVRAAHIDERDSASPQAMIDLLAGLYQGKFLSDSSRR -VILGAMERCRTGTRRIPALLPSNAQVAHKTGSLNN-TSSDIGIIEAPDGRAIAVAIYVTG -QG-SRGAREARIAEIARALYEGy ->[subseq from] Beta-lactamase n=3 Tax=Staphylococcus TaxID=1279 RepID=U6EG14_STASC ---------------------MYALNTQNGKEL-SFNENKRFAYASTLKAISSAMLLEQTP ---YNKLDKKIHINKDDIVPYSPVLEKYIGKEITLKKLIEATMLFSDNTANNKIIDELGGY -EQVKTRLIDLGDTTTYPSRKEPDLNFYSPKDKRDTSTPLAYGKTLKKLIADGDLSKANKD -FLLDLMLKNKSGDTLIKDGAPSNFKVMDKSGQATYGSRNDVAFVYPDGQKPIILVIFTNK -DRKDGKPNDKIVSEVAEIVLK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris CC31F TaxID=1073351 RepID=S3YHW0_BACSE ---TLEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSSQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Ensifer sp. MMN_5 TaxID=2037902 RepID=UPI000C9C848E ---RLRLELETLADGHPGRVGICVQD-QPKAPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD -EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGT -KAIQVFLEKAGLTGVRIDRTERELQTAYMKDPRDTATPRGMAAFLYSLASGSLLTAGSTE -FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE -SRAGQAERAAVIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 12-68-11 TaxID=1970586 RepID=A0A257YJ41_9SPHN ----FEQQLAQLANGARGRIGIAAVDLATGQEI-AVFGDQRFPMASTSKIAIAATYLEGVE -QGRWTLSSEFALRVPVGSRSTAIAPTRDGQVMSAAQLIDLMITRSSNPATDALLKAVGGP -AAVNDWARRAGISEFNLTRDIATLVRAVHVDLRDSATPRAMAQLVSGIYQGKWLSPASRA -VIVSAMERCVTGKGRIRALLPGEVTVAHKTGTLSN-TASDIGVLTTPDGRSLAVAIYVTG -QGG-KAGRDAKIASIARALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDBE95F --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLIIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter aquimixticola TaxID=2489173 RepID=A0A4T3EXR8_9SPHN ----LERHIASLADGSQGRIGVAAIDLATGQQI-SILGDQPFPMASTSKIAIAATYLEMVD -KGQLSLTSEFPLLLPVRSQFSTAVAPVRNGEMPAHQLIDLMITRSSNPATDALIAAVGGV -DKVNDWARRAGIDNFNLTRDIATLVRAVHIDLRDSSTPAAMVELLSGIYQGRWLSAESRA -VIIDAMERCRTGTRRIPALMPDNVTVAHKTGSLNN-TSSDIGILTGPDGRSIALAIYVTG -QG-TRSNREARIASIARAIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000D1ED50A --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTAMPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=2 Tax=Erythrobacter sp. EC-HK427 TaxID=2038396 RepID=A0A5E7YFY5_9SPHN ----FEARLAQLADGSEGRIGVAALDLSTGRQI-SIYGDQRFPLASTSKIAIAAAYLEGVD -QGRWSLTAEYPLLVPNSTPLSSARAPVRQGELPAHELIDLMITRSSNPATDALLAAMGGV -GPVNDWMRRAGITEFSLDRDIATLVRRHYIDPRDSATPEAMVQLLAGIYQGRWLSRESRH -IIIDAMERCRTGSTRIPALMPAGVTVAHKTGTLHR-VASDIGIITGPDGRTIVVAIYVTG -QN-SPTDRNARIATIARALYDGf ->[subseq from] serine hydrolase n=1 Tax=Croceicoccus pelagius TaxID=1703341 RepID=UPI0009EDE959 ----LRQNLFAVARPDKGRIGVAAMDLSTGQTV-SILGDQAFPMASTSKIAIAATFLAGVD -AGRYRLDDKYPLMIPVASRSTSVAPVKPGMELTARSLIELMITRSDNTATDAMLKAVGGP -AEVTKWMRSKGFERFRIDRDIATLVRATGADQRDSTPPNEMVRLIAGLYKGEWLSGESTD -VVIGAMTRTVTGSRRIKAGLPSGVDFGHKTGTLNN-TASDVGFVEMPDGRVVVMAIYVTG -QG-GRPQRDARIAEITRTLYAGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0K0N4E8_ECOLX ------------------------------------------------------------- ------------------------------GTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAX------- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012976700 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLEGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMAGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides salyersiae CL02T12C01 TaxID=997887 RepID=I9SU85_9BACE ----LKADFDKLLQDKQATVGVAVVS-DGRKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD -RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV -EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE -FLEKIMMETVTGKDKLKAGLPPAIVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD -SKEDDKTNAALIAAISQKVYEYy ->[subseq from] Uncharacterized protein n=5 Tax=unclassified Bosea TaxID=2653178 RepID=A0A653TEF5_9BRAD ---RLDAGIKTIEQSTKGRIGVGLIDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAVE -AGKLKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP -QALTAILKDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGNWLREPAHA -ALLDIMLEAKTGPNRIKAGLPEGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAAYLAG -AQVGEKEREAAHAAVARLAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Rhizobiales bacterium 65-79 TaxID=1895815 RepID=A0A1M2YZN8_9RHIZ ----LQAGLDALAKRAPATFGIEVRDLRTGKSW-GVNAGKPLPMMSVFKAPVAAAVLAKAD -NGEISLDQPVSITRKDLRGASRIARNFRGDSFTVRQLLEDMVSQSDNTAADRLIALIGGP -QAVTQFLRLKGIEGMRVDLDEGGVEHAFLADPRNRSTPETAADFLQKLWQGKLLSPASAK -RLLDLMYGQTV-PVRLRAGLPAGVRLADKCGTSVTGAFNDIGVLTWPDGHTVIVAAFLSG -SRASREERTKLFADLARMVAARf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000CFFA34D -hdALQATLERFAQAAPGTLGVVVLDLDRPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGKLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTT-PRRLRAGLPPGVSFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERDRLFADLARAVAS-- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A2A7SJ89_BURGA -hdALQATLERFAQAAPGTLGVVVLDLDRPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGKLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTT-PRRLRAGLPPGVSFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERDRLFADLARAVAS-- ->[subseq from] Serine hydrolase n=1 Tax=Deltaproteobacteria bacterium HGW-Deltaproteobacteria-15 TaxID=2013742 RepID=A0A2N2KBT7_9DELT ---RLRSRVESAIPPSQGVVGVSIKHMESGIVV-AVHGDEPFPMASTFKLPLLVELYAKEK -EGAFKWDDLVEISSTDQHLSSGLTAVYDTPGLSIRNLANLMIIASDNSAADICLSKVGGP -SKVTAGMRKIGIHGIRIDRSCQELILRLAADPADSATPDAMVALLERIWQGRAVDPAASD -AMMKTLNRCRTGANRIRGLLPPSTDVAHKTGTLG-GVVNDVGIITLPDNGHVAIAVMSKR -TRAPREQVERVIADIARYAYDYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CAD7_ECOLX --------------------------------------------------MAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTT--------------------- ------------------------ ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X2T7_9BACT ---ALETELRRLAATLPGTVGIAVHHVGTGRLV-TVDADRAFSMARVFKLPVAIAVLRRVQ -TGGLTLETPITIAPEAYYPYSPLRDAKNRAEVTVRDLVETMMVDSDNTAVDVLMARMGGA -DAVNAELRAAGVPDVSVHRTEGEVMAKFLADSRDTATPTALANLLARLDRGEVLDAERTK -ILVGMLDRNKTGGRRFRAGLPAGVRIGDKTGTNPVGTYNDAALVTLPSGARIALVVMTRE -AGDTGAAAEQLMASVARTVYAHf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aerius TaxID=1837929 RepID=UPI00130FA0B9 ---SFEQAVARVADGSSGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAVAAAFMEQVE -RGKYTLTSEFPLMMPVASKFSTARAPVVPGKFQAVDLIEMMITRSSNPATDALLKAVGGP -AVVNDWARRNGISEFNITRDIATLVRARAIDIRDSATPQAMVKLLAGLHQGKFLSASSRR -VILGAMERCRTGTRRIPGMLPAGARVAHKTGTLNN-TASDIGIIQTPDGRSIAVAIYVTG -QG-SKPARDAKIASIARALYDGy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. 66-12 TaxID=1895714 RepID=A0A1Q3MBV1_9SPHN --nALSQRIAMIAEGSRGRIGVAAIDLVTGQEV-AVLGDQRFPMASTSKIAIAATFLEGVD -QGRFSLTSEYPLMVPVSSKSSAVAPVKAGTYHTAAELLELMLTRSSNTATDGLLKVVGGP -AAVNDWARRAGITSYNLTRDIATLVRSSHVDIRDSVTPRDMARLLAGLYQGKWLSPASHD -LLISTMEKCRTGPRRIPALLSAEVTVAHKTGSLNN-TSSDVGIVTGPNGHPVAMAIYVTG -QGAR-AKREDRIAMIARELYDGy ->[subseq from] Veb-1 n=1 Tax=Sphingobacterium deserti TaxID=1229276 RepID=A0A0B8SYQ6_9SPHI --kSLENDIKTFIHDKKAIVAVAIKNGREGDIV-HVHADEKLPMQSVFKFHIAVAMLTEID -KGNFKLQQPIVIKKEDLTPWSPLRDAYPQGTMPLSTVITYMVSQSDNVACDIVLKLLGGP -EVVDQFYKEKGVKDLSIKINEKTMQRNWEAQFKNWTTAEECTDLLKTYFYKKELSAESHQ -FLWTVMKGTETGLKRLKGNLPANTAVAHKTGYSGTEAVHDIGVIYLPNNDPIFISVLVSK -SREDLATNEEIIARIAHMAYDFy ->[subseq from] Serine hydrolase n=1 Tax=Chryseobacterium sp. G0162 TaxID=2487063 RepID=A0A3G6S498_9FLAO --sELKKAIETILAHKKADVGVSIVTAGTKKEViQINGNKPLPMLSTFKFPVALAVLHKVE -KGELSLQQKIYIKKEELLEYSPFKDKYPDGNLSLEDCIQWMVVYSDNNLTDILLRLIGGP -DYVQQFINS---KNIVIKNDEEGMHKDWDSQFINTITPNEATQLLEQFYTGKILNKEHTK -WLYTAMLNNATGAKRLKGKLPKDVKVAHRTGTSFTGAVNDYGIIELSDKKRIYIAVLVHD -TYETFENSEAIIADIAKAAYNHy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0U5IQE6_9BACT ----PQQDFKELEKKYDAHLGIYVIDTATNKKI-AYHANERFAFTSTYKVLAAGVLLQNYS ---LEQLETVIPYTKDDLVAYSPVTELHTDTGMTLREISEAAVRYSDNTAGNLLFHAIGGP -KGFEKSLRKMGDKTTYANRFETELNTAIPGDKRDTSTAKALAKDLKKLTVGSALPAGKQQ -LLLDWMTDNKTGDALIRAGVLKG------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=B2CD67_KLEOX ------------------------------------------------KHMLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWYFAD-------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Phenylobacterium sp. CCH9-H3 TaxID=1768774 RepID=UPI00083A02FA --------ISAIAGAAPASLGVGLSNLESGQTY-TFNGDRRFPMQSVFKLPLAAAVLAEAD -AGRLMLTEPFVLTEEQLSPVSPIAAGWPARRYTAQALFEAMVVDSDNTAADVLMKRIGGP -GAVTAWLTARRVPEVRVDRYERELQPRYMSDPRDTTTPRGMLELLQMLDRQELVSPASTK -RLLELMGRTRRGVGRIRAGLPRDAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG -STLDEAGRDRIIAEVARAAL--- ->[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI000B9545AD ------------------------------------------------------------- -----------------------MTKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI -QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK -NKKGAVSPDSIIERITRILM--- ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia TaxID=32008 RepID=A0A560UVK9_9BURK -hdALQATLERFAQAAPGTLGVVVLDLDRPSRW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGKLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTT-PRRLRAGLPPGVSFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERDRLFADLARAVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium lindaniclasticum LE124 TaxID=1096930 RepID=T0HQ21_9SPHN ----FGKQLASVAEASRGRIGVAAIDLSSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWSLSSEFPLMVPVPSASSAIAPVRPGTYMSARQLIEIMITRSNNYATDALLKVVGGP -SAVNAWVRRTGIEEWHIDRDIATLVRARVVDKRDSATPIAMAQLLSGIYQGKWMSKQGRD -VLLGAMSRTVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG -QG-TRPNREARIASIARTIYEGy ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E7UD97_9SPHN ---RARAQLVDIEKRSGGRLGVALIDPAGEVLL-SHRGEERFAMCSTFKTLLAGMVLSGET ---GLEQEDRLTIDPAEVEGHAPFTRSRFEEGMTVGDAAQNIVTVSDNGAANLLLDEVGGP -RGLTEWIRALGDDVTRLDRRELALNENAADDPRDTTSPLAFGETYRRVLSDDVLDASGRE -RLAQWLEASETGLNRLRAGMPGDWRVGDKTGYCAAVEINDVAIFDPAGGGWYTLVFFLDR -PREAGAFADALGAEVGAIAAD-- ->[subseq from] Class A beta-lactamase n=1 Tax=Asaia sp. W19 TaxID=2067395 RepID=A0A433WYQ0_9PROT -----------YEKGCGGRLGVHIFCPETGAAL-TWRGNERFLMCSSFKASLVACVLARCD -RDEDELTTHLPFLDSDFTAWAPVARKNRDAGLSLAALCAGAVTASDNVCANMLLRHIGGP -AALTHFWRESGDEITRLDAYEPELNRPSADAAANTTSPVAMARTLHRLVHGTLLHPNSAA -LLRNWMISCNTGTHRLRAGLPPHWISGDKTGNNGQDIAADIAFAAPDPGKSLIIAVYTAG -GTPDETRFRNVFHELGAL----- ->[subseq from] Beta-lactamase (Fragment) n=6 Tax=Bacteria TaxID=2 RepID=C7F8X0_ECOLX --------------------------------------------CSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKT------------------------------ ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Bosea sp. F3-2 TaxID=2599640 RepID=A0A5C1B535_9BRAD --aKLDKEIIAIEEQAKGRLGVALVDLKDRKQW-SYRGAETFPLQSVFKLPLAVAVLQQVE -AGKFKLDQPITVTRQDFSLNSPLAKAFKGERYPLSELVRLAAGQSDNTAADLLMREIGGP -QVVTKMLRDGGITGISIDRYERQFQPKALKDKRDAATPEASALFLEAFAKGNWLRPAHTA -FIEKIAAEMKIGAERIKAGLPAGSRLAHRTGLGLNHASNDIGIATLPDGRRFVIVVYLAG -SRADANERDAAHAAVARLAVS-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SV74_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGEILQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHQNPQKAYANWSTPSEMVRLLKMADEKDLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000CD29E66 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KGFQQALIHRGDHITNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE -LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. cv1 TaxID=1622071 RepID=UPI000C77626C ----LVRQIDSVLSRYRATVGVTVLS-NRDEIV-AANDSILFPLMSVFKFHIALAVLDRMD -RNRTRLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP -EVVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK -FLIRIMTETSTGQDKLKGLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD -SQEDDPTNASIIARISAIVYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D1KRK6_ECOLX ---------------------------------------------------------ARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVSLLGP-------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI000B58CC99 ---TLDDSFKNLEDEYHGKIGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -TSVKALSNEKIIQQASKLTA--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A1W6AL12_ECOLX ------------------------------------------------KVMAAAAVLKXSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonadaceae (miscellaneous) TaxID=122612 RepID=UPI0010F435A6 ----LDDRLFQIWKAFPGKTGIAVQRIDGEWTL-TQRGNELFPQQSVSKLWVALAVLDAVD -NGRLRLDQNVRIGPEDLTLHQPIAGRVQAQGMTVRELIETAITQSDNTANDSLLRTVGGP -DAVRRFIDKKDLGAIRFGPGERLLQAAYRADPPDGASPAAIANALTRLARGALLSPESTQ -YLLGVMTRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVLMGE -ASSPVPARMATMQSVSRAVAEY- ->[subseq from] Class A beta-lactamase n=1 Tax=Flavobacterium sp. IR1 TaxID=2026304 RepID=A0A270QJE2_9FLAO --tELRKKIEHLISNKKLTAGISIKRIEDQDTL-SINGNLEAPMMSVFKFHIALTVLDLVD -NGKLKLNQSFFIKKEELLPWSPMREEFPEGDLTLDQLLRYTVSHSDNNGCDILLRQIGGT -ETVQKFINSQGIKDFTIKVNEEEMST-WENLYVNTTTPLATTTLLEKFYKGQVLKETSTK -YLYQIMVETSRGLTWMKAGLPKNTELAHRTGISGTNAMNNIGIFKLPNRQHVILCIYLKN -ISISMKATEKLMADITKAVWKHy ->[subseq from] Beta-lactamase n=1 Tax=Microscilla marina ATCC 23134 TaxID=313606 RepID=A1ZTJ7_9BACT ----LKQKIHQVFKGKSATVGVAIRGSNSADAI-SINGNKRLPMQSVFKYHLALAVLHQVD -QGKFSLNEKIAITQKMVNAWSPLRKKYPNGALTLAEILRYTVAWSDNLGCDVLFKLIGGT -KVVESYVHKIGVKDIAIVHNEIVMQAKWKHQYENWTTANAANQVLQLFFEDNLLSTKSYN -FLLDVLKGTKTGKKSIRGLLPKDAVVAHKTGHSGTGAVNDIGIVFLPDNSYFYVSVLVSN -SLESDATNQKIIADIAKLTWDYf ->[subseq from] Serine hydrolase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=A0A2W4SKC3_9RHIZ ---RLDREIAAIEKQSQGRLGVALLDLRDRKTW-SHRGSESFPMQSVFKLPLAIAALQAVE -AGRFKLDDRITIRRSEFSLHSPLAKAFKGESYALRELIRLTAAESDNTAADNLMRRIGGP -KVVSDMLRAGGIVGISVDRYEREFQPASFKDKRDTASPSASVLLLEAVAQGNWLRDPSHN -SLIKHMLDNAGGRERVRAGLPAGSRFAHRTGAGLNHATNDIGLVTLPNGRVFAIAVYLAG -SRADAKTREAAHAAVAKAAV--- ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia subsp. philomiragia (strain ATCC 25017) TaxID=484022 RepID=B0TXT1_FRAP2 ---TLDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNQNYHFPICSVFKFLLVGAVLEYDM -QHEGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINYTKPDSNINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -PSVKAPSNEKIIQQASKLTA--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Paraprevotella xylaniphila TaxID=454155 RepID=UPI001032D1A8 ---DLQEQLRRMVADKKAQVGIAVI-LDGRDTL-TVNNDVRFPMMSVFKFHQALAVADACG -QRGVSFDTLVHVRPDDLHPYSPLRDKYPDGNLSVGELLKYTLHLSDNNACDILFRVFGGP -AATDEYLRSMGLRDFAIEVTEDDMHRNLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD -FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGHRYSIAVLVRD -SEESEQATARVIADISEAVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. KEM-5 TaxID=2486356 RepID=A0A5S3P1P6_9SPHN ---ALDRRIAELAEGSNGRIGVAAIDLATGQVV-KVLGDQRFPMASTSKIAIAATFLEGVE -QGRWSLTSEFPLLMPRSSASSRVAPVYEGQYMPARELIEIMITRSNNYATDALLRVVGGP -ERVNDWARRNGLSEFSIDRDIATLVRANHIDLRDSATPMAMVQMLGGLYQGKYLSADSRR -VLLGAMSRTRTGKRRIPAMMPAGVRVSHKTGSLNN-TSSDIGILEMPDGRAIALAIYVTG -QG-TRLNREAKIAAIARAIHDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A3S7Q8J3_9ENTR ------------------------------------------------------------- -------NQRVEIKLSDLTNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -GEVTAFARAIGDRTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGNALGETQRA -QLVTWLKGNTTGAASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPQGRAP--------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Empedobacter brevis TaxID=247 RepID=UPI00132016E4 --eRLRTEINQIISSKNLTAGISLKNIENKDTL-SINGNQMMPMMSIFKFHIALTVLHEVD -QNKLQLNQKFFIKKRDLLPWSPILDDFPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT -KIVQNFIHKQGIKDFVIKVNEQEMQK-WDNLYINTTSANATAKLLEKFYTNKVLKKNSTT -YLYQLMVETSRGSTWMKAGLPANTELAHRTGISDTNAMNDIGIIKLVDGKRIILSIYLKN -ITEERAETEKVMADITKAVWNYy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A412T0Z3_BACSE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGEI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGIVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Legionella saoudiensis TaxID=1750561 RepID=UPI0007311119 ---ALAKKIRDIEKKSHIVMGITAIHIEKNQII-THNSNQRFFMASTIKLPIALAFLHLVD -QKKESLNRMIKLSTKNSVPGSGYLHHIFEKKISLQQILKYTLINSDNSASDSLLNAAKGP -EAVKKRMAALGFKDIQINRSIKEMFVRFENDSRDTTTPNDMAKLLVKVYKKQALSESSTQ -LLMKIMEQCRTGRSRIRGLLPPGVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8BA8 ---RLEQELVRLSDISGGKVGICAVHLESGKTI-SQNGKDHFPMASSYKVAIATQLLSRVD -SGSITLDQLIPITKNDLHPGSGMLS-----PLSVRSLLELMLLISDNSATDVCLRLAGGP -DAVNACMKRLGIDGLQVNRPTAWLIAAFENDIRDTSTPEAMTLLLSKLYTQSILKSDSKA -LMLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGLITLPDNGHVAISVFVKS -SKKDGALRERAIAEVTRTIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Kozakia baliensis TaxID=153496 RepID=A0A1D8UWK6_9PROT -----KQLLSEIEKKLGGRVGVSAVDTKTGLAL-QWRGSERFVMHSVFKWLLSAYLLHCSD -TGSRPLQTSVVIKTSSIVGHSDQTKPFAGTAVTIETLCFWMMSTSDNGAANTLLDVIGGP -SVLTSWLRSLGDTTTRQDTYEPGPTEG-SIDPRNTTTPDAMLALTQKIWMGSVLSPGSRE -TLLAWLQSSAVGGRRLRAGVPSSWVEGDRTGTGDPGVADDVAIFWPDGHKTILVTSFLEG -STNSLARLESAQASIGQILANLf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FDA152D --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIETVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATISAAARAITAAy ->[subseq from] Beta-lactamase n=2 Tax=Algoriphagus TaxID=246875 RepID=A0A0P7Y425_9BACT ----LLTQIEQIVSDKDAIVGVSIIGNNGKDTL-SLHGNMRFPMQSVFKFQVALAVLGEID -QGNISIDQKIEIEKDEFLPWSPLRDAYPNGGFSVEILIQYCVSHSDNSACDILIQLIGGP -KTVESFIKKTGVEDLQIEFNEEKMQSKWENMYHNWTTPNAASETLKLFYENKLLSKVSYD -FFWKTMKETTTGKNRIKGLLPIETIVAHKTGWSGTAALNDVGIVFLPNNEYFILSIFITE -SRENFDTNEKIIAEIAKAAYDFy ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium TaxID=165696 RepID=A0A158SRP9_9SPHN ---QFEKQLASVAEASKGRIGVAAVDLATGRTI-EVLGDQRFPMASTSKIAIAATFLAGVE -KGKWSLTSEFPLMVPVASASSPVAPVRPGAYLSARELIEQMITRSNNYATDALLKVVGGP -KAVNDWVHNAGIEDWHLDRDIATLVRAQVIDKRDSATPLAMVKLLNGIYDGKWMKAESRD -VILGAMSRCRTGRRRIPAMMPDGVTVSHKTGSLNN-TSSDVGIIQTPEGHAFAVAIYVTG -QG-SRPNREARIAQIARAVYDGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L0A1_9BACT --sELKNRIDSLLNSKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=G3JXZ1_KLEPN --------------------------------------------------MAAAAVLKKCE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTK--------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Dyella thiooxydans TaxID=445710 RepID=A0A161IV29_9GAMM --dELQARLQALSRQAPGRLGVTVLDLRDGHAW-RTGADRAYPMMSVFKAPLGAALLARVD -AGTLSLDRQVTITRADLRHRSAIADRFHGEAFTVRELLVAAVADSDNTAADALLPLAGGP -AGVTAFLRSHGIDGLRVDRGEGAIYHAYMAGPRDTSTPDAAASFLRQLWQGELLSAPSTR -LLLDTMTHTPP--FRIEPGLPKSVRFAHKGGTSATAAFNDIGVIAWPDGRAVVVAAFLTG -STQSAKERNALFAELGRVVVR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPH0_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDILLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF29-11 TaxID=2292928 RepID=A0A3A5X1S1_9BACE --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000BD3AD4B ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSLVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLL----------- ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B1AGF4_9BACT ----LLAEIERLAPSSGGTVGVGAVHIETGRAV-WFNEDERFPMASTYKVPIAVQLLSRVD -RGEITLADMVELEPGDIHPGSGTISNLFDDPLSLRNLLELMLLISDNSATDLTLTAAGGP -DAVNARMSELNVDGLSVNRPTSVLIGAFSTDLQDTSTPRAMAHLLAMTWAGKALGSKNTE -VFKDVMLRVQTGTGRIKGVLPPGTPVGHKTGTIG-GTTNDVGYIYLPDDGHVITVVFVKD -SERPVPAREATIAQISRAIYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Fluviicola sp. RIFCSPHIGHO2_12_FULL_43_24 TaxID=1798019 RepID=A0A1G0CC29_9FLAO ---DLKAELEQFLSQCRATAGVSVKVLEDGEAF-TINDTVLHPTLSVYKFPLALAVLHKVD -KGKLKLDQTVHITKEMLHPWSPYRDVHPEGNATISELLAYSVSRSDNNTTDILFDLLGGP -AKVHQYIAGLGIKDMMIAANEYEMGEE-NRLYDNWSKSAAMVDLLGKFYSKKVLSEENTQ -LLVKLMTDTPTGINRMKGLLPATAIVAHKTGTSGTNAVNDVGIITLPNGKHIAIAVFVTD -SKESFETNEYIIAHIAGAVWNHy ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD221AD --dRLRSELTVLANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAGTDVLISHLGGT -KAVQAFLDQAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPERLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. CF476 TaxID=2135474 RepID=A0A318XH89_9BRAD ---KLDAGIKTIEQSTKGRLGVGLIDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAVE -AGKLKLDQPITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLVGGP -QALTAVLKDGGVTGISVDRYERVFQPATLTDRRDAASPDASIAFLEGLAKGTWLRDPSHA -ALLDIMLEARTGPNRIKAGLPAGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -AQVGEKEREAAHAAVARLAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Bosea sp. FBZP-16 TaxID=2065382 RepID=UPI000C30877B ---RLDSGIKTIEQGTKGRIGVGLIDLKDRKSW-TYRGAEPFPLQSVFKLPLAIGVLQAVE -AGKFKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP -QALTTLLRDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGNWLRDPANA -ALLDIMLEAKTGPNRIRAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -AQVGEKEREAAHQAVAKLAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=UPI0009A1A77B ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATPR-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. B04 TaxID=1945860 RepID=A0A1V3QJP1_9GAMM ---RLQRTLAALAQRAPGTLGVAVLDLQSGVEA-GVNAGQAFPMMSVFKAPVAAAVLSRID -AGKLSLQQQVIVTRADVLNGSPSIGAHFRGEFTVEQLLQAAVSESDNTAVDALLKLVGGP -QVVTAFLRAHGIAGMRVDLDEAGVGRAFLAAPTNRSTPDAAVSFLRKLQGNELLTPASTQ -HLLDLMAAQTI-PNRLRAGGPHGVRFADKTGTSDTAAFNDIGIFTGPDGHTVIVAAFLTD -SPASQAQRDALFADIARAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SQ41_9BACT ----LKADFDKLLQDKQATVGVAVVS-DGCKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD -RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV -EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE -FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD -SKEDDKTNAALIAAISQKVYEYy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides salyersiae TaxID=291644 RepID=A0A5M4ZAC3_9BACE ----LKADFDKLLQDKQATVGVAVVS-DGCKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD -RKQLPLTTEILIRKADLLPYSPLREARPEGGMSVGELLRYSVSESDNNACDILFRYIGGV -EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE -FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD -SKEDDKTNAALIAAISQKVYEYy ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea lupini TaxID=1036779 RepID=A0A1H7SG78_9BRAD ---KLDAGIKTIEQGTKGRIGVGLIDLKDRKSW-TYRGGEPFPLQSVFKLPLAIGVLQAVE -AGKFKLDQPITVTRNDLSLHSPLAKGFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP -QALTALLRDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGNWLRDPANA -ALLDIMLEAKTGPNRIRAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -AQVGEKEREAAHQAVAKLAVE-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A412JR08_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVQECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQVNNKIIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces rubellomurinus (strain ATCC 31215) TaxID=359131 RepID=A0A0F2T9M0_STRR3 ---DVGRRLAELEQQHGGRLGVYARNLRTGRTV-RHRADETFPICSVFKTLAVAAVLRDLD -HDGEFLARRIHYTVDDVKNGAPVTGKNLANGMTVGELCAAAIDQSDNTAGNLLLRELGGP -TAVTRFCRSIGDRVTRLDRWEPDLNTAEPDRTTDITTPHAIARTYRRLVLGHALPPAQRR -RLTDWLLANTTS------------------------------------------------ ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Pseudoalteromonas phenolica TaxID=161398 RepID=UPI001375F287 --------------------------------F-SFNGDSKLPMQSVFKFHIAAAVLSEVD -KGKWSLEDKIKITPNDLDNWSPIRKKYPTGTLTLSEVIRYTVSVSDNVGCDILLSMLGGP -KKLEDYLHQSGIKDIAVIYNEENMQKVWQRQYENWTTANAANTALRQFYIKNLLSDKSHQ -FLWDVMKGSKTGRKTIRAGVPKDIQVAHKTGHSGTGAQNDIGIVFLPSGQHYYISVLVSD -SYETSETNQNIIAKISELTWQFf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:189 TaxID=1262737 RepID=R5JPT4_9BACE ----LKADFDKLLQDKQATVGVAVVS-DGCKTF-TYNNQHHFPLMSVFKFHQALAVLNYLD -RKQLPLTTEILIRKADLLPYSPLREARPKGGMSVGELLRYSVSESDNNACDILFRYIGGV -EVVDKYIRTLGITDFKIEATEEDMHEGFRYQYLNWTTPLAAVRALEKFCTETLFRHSYKE -FLEKIMMETVTGKDKLKAGLPPAVVLGHKTGSSDKAGDNDMGFVRLPDGSRYSIAVFVKD -SKEDDKTNAALIAAISQKVYEYy ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127SML6_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDILLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHRNPPKAYSNWSTPSEMVRLLKMADEKNLFAPVYRD -FLWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVITPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A562AA ------------------------------------------------------AVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KEPTAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGTG--------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Enterobacter hormaechei TaxID=158836 RepID=UPI00101C5D53 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMAALLQ-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. dk3624 TaxID=2662363 RepID=A0A5Q0PZR7_9BACT ----LVRQIDSVLSRYRATVGVTVLS-NRDEIV-AANDSILFPLMSVFKFHTALAVLDRMD -KNRTPLDSVVRIKASDMHPYSPLRERHPGRDITIAELLRYSVAHSDNNACDILLEYAGGP -EAVEKYVRGLGIENTFISASEKTMHDRIENQYLNRSTPTATARLIETFFENRLFASKYKK -FLIRIMTETSTGQDKLKSLLPPDCTVGHKTGSSDRTADNDAGFVLTPDGKRYYIAVFVSD -SQEDDPTNASIIARISAIVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Flavobacteriaceae bacterium TaxID=1871037 RepID=A0A348XZ72_9FLAO --eSLRTEINQILSSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD -QNKLQLNQRFFIKKEDLLPWSPILEDYPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT -KTVQNFINKQGIKDFIIKVNEQEMQT-WDNLYLNTTSANATTKLLEKFYATKVLKKNSTT -YLYQLMVETSRGLTWTKAGLPENTELAHRTGISDTNAMNDIGIIKPINHQPIILSIYLKN -ITEERTETEKVITDITKAVWNYy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. HN-Y73 TaxID=2320269 RepID=A0A420ELM3_9SPHN ----LEQKVALLANGEEGRIGVAAIDLSSGHEI-AILGNQRFPMASTSKIAIAATFLDGVD -KGKLSLTSEYPLMIPVSSKSSKVAPVRKGQYLSARRLMELMLTRSSNSATDALLAALGGP -DVVSKWVHSTGITDFQLSRDIATLVRVAQIDPRDSATPLAMVQLLKGLYQGEWLSEKSRR -FLIDTMEQCRTGRRRIPALMPEDVTIAHKTGSLHN-TSSDIGILTAPNGKSYAVAIYVTG -QG-TRANREAKIAHIARAIYDGy ->[subseq from] Beta-lactamase class A n=2 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560K8P7_9PROT ----LQARLDRLAHEFPGRAGIAVRDGLTGAEA-GVKARERFPEQSVFKLTVAIALLDLVD -HGRMDLAQKVTLYPRDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP -AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLERLDKGELLSPASTR -RLLDILDHTTTQPNRLKAGLAAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS -VQGPRERADAFIAGVARAVVESw ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A412N6N1_BACVU --sKLETQLKQAIKDKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQVNNKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Gluconobacter cerinus TaxID=38307 RepID=UPI000C074231 ------ERLQAIERASGGRLGVFVLDTGSGQSV-GWRADERFCHCSTFKLSLAAMALRESD -ANRLDLAETLTFSRADIVGYSPVVERNLAKGLPIITLVEAVQVTSDNAAANVLMRRLGGP -SAMIRFRREIGDNKSRLDGYEPAINVIAPDTEENSTTPRAMAETVRRIVLGDVLSSLSSD -RLRGRMAVTQSGLQRIRAGIPASWRGYDKTGTGMGNKTNDLAVLVPPDRSSLVVIGYFEN -PL--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8HEF9_9BACT ------ATVQKLAHSLEARVGMAAVMLDTGETV-SIGDEAAYPMQSVFKFILALSVLKQVD -EGKLDLEQIIHIRPEQLLKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -GTVQKDLKEWGISGINVRFTENEMLRNHDLQYVNSSRPSAMNALLRAFDEGKILNKDTQR -FLWDIMAGCSTGATRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSLPACEKVIASMARWLCTEw ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HN-E23 TaxID=2488860 RepID=A0A3N5D9E4_9SPHN --nQLELRIAQLAEGSEGRIGVAAVDLATGQTI-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWSLSSEFPLLWAVRSQSTRVAPVREGEYLSARRLIELMLTRSSNQATDALLKAIGGP -SAVNDWAHRAGLSEFSLDRDIATLVRATFIDERDSASPETMVQLLAGLYQGRWLSQASRE -FIIDTMERCRTGTRRIPAMMPGGVTVAHKTGSLNN-TSSDIGILTSPDGRAIALAIYVTG -QG-SRLARERRIASIARGIYDGy ->[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Root483D1 TaxID=1736544 RepID=A0A0Q9ICQ9_9BRAD ---RLDSGIKAIEQSTKGRLGVGLIDLKDRKSW-SHRGAEPFPLQSVFKLPLAIGVLQAVE -AGKFKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLIGGP -QALTAILKDGGVTGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGTWLRDPANA -ALLDIMLEAKTGPNRIKAGLPAGARFAHKTGLGPNHATNDIGIVTLPDGRRFAVAVYLAG -AQVGEKEREAAHAAVARLAVE-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D1C54E1 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KGFQQALIHRGDHITNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE -LLKHTMIHNETGDTLIKAAISKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A3N7GJ16_9FLAO --qNLKRDIRKITRGKKATVAVAVRSIDRPELHyGLNGGLHVPLQSVFKFHIAMAVLADVD -RGRFYLSQKIPVKASELREWSPLKEKYPIGDIPLIELLTYTVAQSDNNGADILIRLIGGP -EKVQAFINGKKITDFNIAGGEAYMAENWNNQFNNWSTANSVTETLIRFYNGDLLSPDSTE -FLYDTLVSTTTGKNRLIAGLPTEAVLAHKTGSSATAAVNDAGLVVLPDGRSYAISVFVTD -SKESEAVNEKVIADISKAAYQYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL41_ECOLX ------------------------------------------------KVMAAAAVLKQSX -XQKQLLNQPVEIKPXDLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRXLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYG------------------------ ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseolinea flava TaxID=2059302 RepID=A0A364Y210_9BACT ---ALKSKISSIVKSIDADIGVSMFHVEKKDTL-SLQGTKHYPMQSIYKFHLALAILEQVD -KGNIKLEKKVRIYPDQYFKHSPIIKTYPEGNLSVTQLLEYTIIESDNLGCDLLFDLIGGP -EKVNHFIHTLRIKDVSILNTEREMHVTPDLQFQNWTTPIAMSTLLREFYLRKVLQATTHD -FLWTTLSKTSVGPRRIKGLLPSGTVVAHRTGTGDRDAVNNAGIIVLPNGDHVVLSVFVTH -LRGEIKDGESAIAEIAKAVYDHy ->[subseq from] serine hydrolase n=1 Tax=[Scytonema hofmanni] UTEX B 1581 TaxID=379535 RepID=UPI0004985F33 ---SLKAAVQNLALASNLTPGVFLVDLNSGGYV-DINAGASFPAASTIKVPILVALFQDVD -AGKIRLDEILTMQQDMVAGGSGIQYKPVGTQFTVLELATKMITISDNTATNMLIAKLGGI -DALNQRFRSWGLTTTAIRNKLPDLEGT------NTTSPKELGNLLAMVNQGNLVSMQSRD -RLLDIMRHTER-DTLLPSGLGAGATVAHKTGDIGT-MLADAGLVDMPNGKRYIAAVMIQR -PNND-PRAEKLISAISSTAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides oleiciplenus TaxID=626931 RepID=A0A3E5BLR2_9BACE ---GLEQQIEQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KEHVSLDSIMEIKAAQMLPYSPLRQKFPDQDISLRELLEYSISLSDNNACDVLIDYAGGI -EKVNSYIKSLGLKDFNLAANEDLMHRDVATQYQNWSTPEAVVRLLDIADKQTLFATEYKD -FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGREYYITVLVME -SQENDQENAAIIARISKIVYD-- ->[subseq from] Beta-lactamase n=6 Tax=Bacteria TaxID=2 RepID=A0A127T508_9BACT --sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1R774_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRR------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=A0A561H389_9GAMM ---RLHETLERLADEAPGVLGITVVDLDTHART-RVNADRAYPMMSVFKPPVAAAVLAQVD -AGHMSLDEEVTIRRGEVVDGSAVPAHFVGDRFTVEQLLEAAVADSDNTAVDALLRRLGGP -RNVMTYLHAHHVDGMRIDLSEGDVSRAYLKDPRNRTTPDAAAVFLEKLWAGELLSSESTK -RLLDLMYRQTT-PNRMRAGLPADVRFADKCGTSYTAAYNDIGIVTWPNGHTVVVAAFLTA -SRADKPARDALFAKLGKALVE-- ->[subseq from] Beta-lactamase n=1 Tax=Paraprevotella xylaniphila YIT 11841 TaxID=762982 RepID=F3QPU2_9BACT ---DLQEQLRRMVADKKAQVGIAVI-LDGRDTL-TVNNDVRFPMMSVFKFHQALAVADACG -QRGVSFDTLVHVRPDDLHPYSPLRDKYPDGNLSVGELLKYTLHLSDNNACDILFRVFGGP -AATDEYLRSMGLRDFAIEVTEDDMHRNLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD -FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGHRYSIAVLVRD -SEESEQATARIIADVSEAVYRY- ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. 7_F195 TaxID=2258963 RepID=A0A3D9BAE2_9FLAO --tTLDQKINIITKDKKATVGISVVGFDHHFKY-SKNGDLKLPMMSVFKFHIACTALDLVD -HGKLSLDQKVFIKKSDLHEWSPFRDQHPKGNASLREVIDYTVALSDNNLCDVLLNLIGGT -KAVQQFMNSRGVKNFQIRHNEHDMAKGWDSLYENYSTVNSITEVLKKLHYGKLLSKNSTD -DLIQMMLGTKTGMNKLVEQLPKNTPVAHKTGSSGKRAENDMGIVTLPNGKQYAIAIFVSN -STETDATNCKIISDISKTVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E2D6EA9 ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAERNQQI------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides oleiciplenus TaxID=626931 RepID=A0A1Q6GSH6_9BACE --kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYAGGI -DKVNSYIKSLGLKDFNLAANEELMHTNVATQYQNWSTPEAVVRLLNIADKQTLFAAEYKD -FLWQILKETSTGTDKLKGQLPPDVIIGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] Beta-lactamase n=2 Tax=Erythrobacter nanhaisediminis TaxID=604088 RepID=A0A1I5L686_9SPHN --nALEQTIAELADGSKGRIGVAAVDLSTGKTV-SVLGDQLFPMASTSKIAVAATFLEGVE -KGKWSLTSEFPLLLPRRSASSPRAPVYEGQYMKAIDLIEIMITRSSNPATDALLRVVGGP -EAVNDWMRRQGIDEFSIDRDIATLVRAQHIDPRDAATPKAMLELLTGLYQGKYLSSESRR -VLLGAMSRTRTGKRRIPALMPASVKVSHKTGSLNN-TSSDVGILETPDGRAVAVAIYVTG -QG-SRLNREAKIAQIARALHDGy ->[subseq from] class A beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=UPI0005A577C1 ---TLDYSFKNLEDKYHGKIGIYTLNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSNINKTTPKAITQDIYNLSFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -PSVKAPSNEKIIQQASKLTA--- ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium aurantiacum TaxID=2116499 RepID=UPI000D1262D2 --tELKKIIESIIAGKKADVGVSIMETPKKEVI-QINGSKFYPMLSTVKFHIALSVLHQIE -KGELSLQQKIYIKKEELLEWSPFQKEHPEGNLTLEEAMKWMVSYSDNNLTDILLRLIGGP -QTVQKFINS---KEFVIKNDEEGMHKDWDSQFINVTTPNEAIKLLEQFYNGKLLNKEHTK -WLYTAMLNNASGAKRLKAHLPKNFKIAHRTGTSFTGAVNDFGIVELPEKKRIYIAVFVHN -SYESFDNTEAIIADIAKATYDYy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Microscillaceae bacterium TaxID=2053581 RepID=A0A349E4P4_9BACT --qALKEKINQVLKGKSATVGVAIQGANPKERL-SINGDKHLPMQSVYKYHLALTVLHQVD -QGKFSLDQKITLDKKMVEAWSPLRKKYPNGTISLAEVIKYTVAWSDNLGCDLLFKLIGGP -KIADAYMHKIGIKDIAIVYPEIVMQAKWHIQYENWTTPKAANQALQLFFENNLLTQKSHD -FLLNVLKGTKTGKKRIRGLLPKETVVAHKTGYSGTGALNNIGIVFLPDNTYFYISVFVSD -SSESNATNQQIIAKIAKLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. GDMCC 1.1288 TaxID=2282649 RepID=A0A3E1YG65_9BACT ---SLKSDVQALIAKSKSRVGVSVIGPEGNDIL-DLKSGERFPMLSVFKFHIGLYVLHLVD -KKELTLNQLVHIDSSDLMKWSPLAKLYPNGNLPLEKILSYTISQSDNNGCDILLKLVGGP -DSVQNYMKKLGVKDISIVATERDMHASWEAQYKNWTSPWAATHLLKAMDENRILSRSSTS -VMLKFLMETAI-TDRLNGLLPKGTKVAHKTGTSGTPATNDIGIIELPNGQHYYIAVFVND -SWESDKKNARLIAEISKAVWDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL45_ECOLX ------------------------------------------------KVMAAAAVLKKSE -SXPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPXSWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0IMS5_9SPHN ---KLLGEFERFATLSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID -AGDVRLDDQLTLDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP -AAITQFVRGLGVDGLRVDSDTAHLLYAFAAEIEDTSTPRAMLDLLTAYESGKALSADSTQ -RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAVVAFVMK -DSKGHKSRDRIIAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter atlanticus TaxID=1648404 RepID=A0A0H4VW64_9SPHN --nQLELRIAQLAEGSNGRIGVAAVDLATGQTI-SVLGDQRFPLASTSKIAIAATFLEGVD -QGRWSLTSEFPLMVPVGSRSSHAAPVRRGEHLSALRLIDLMLTRSSNTATDALLAAIGGP -QAVNEWARRSGLQNFSIDRDIATLVRVVHIDPRDSASPAAMVQLLAGIYQGRWLSSRSRE -VIIDAMERCRTGTRRIPALMPSNVTVAHKTGSLNN-TSSDIGILTAPDGRAIAVAIYVTG -QG-NRLNRERRIASIARGVYDGy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A6A1XN92_BACOV --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter xinjiangensis TaxID=762261 RepID=UPI000F7E3CD0 ----LEQRIAELADGARGRIGVAAIDLVTGEEV-SILGDQRFPMASTSKIAIAATFLEGVD -QGRWKLSDRFPLMVPVASRSSEKAPVRPGTVLSASQLLELMLTRSSNTATDGLLAVVGGP -SAVNDWATRAGIPNFQLTRDIATLVRAVQVDVRDSTTPRAMTKMLVGLYQGKWLSRSSRN -LLIGIMEKCRTGVRRIPALLPDGVTVAHKTGSLNN-TSSDVGIVTGADGHAIAVSIYVTG -QG-SRPGRESKIAHIARALYEGy ->[subseq from] Beta-lactamase n=1 Tax=gamma proteobacterium NOR5-3 TaxID=566466 RepID=B8KHB2_9GAMM -----SNLLKTLTKDLVGVLGVAAQRPGYQGRI-LVNADEPFPMASTYKIPIAITLLRRID -QGELRLDQLVPVPDEAVVFSQIIASAFPHSGISVANLIEVMITYSDNTATDICLELAGGP -EAVTKTMRSLGIQGLHVDRSTAELLKDFEADGKDKSTPRAMLSLLLALKAGETMSQAGTD -FLLGAMSRTVTKPDRLGRLLPKGTQVLHKTGTVG-GVVNDVGYIRLPGGDEFAIVVFTKS -STTDPADRERAIGEVARSLYDYf ->[subseq from] serine hydrolase n=1 Tax=Croceicoccus sp. S2-4-2 TaxID=2571150 RepID=UPI001181FF0B ----LRQNLFAVARPDKGRIGVAAMDLSTGQTV-SILGDQAFPMASTSKIAIAATFLAGVD -QGRYRLDSKYPLMIPVASRSTSVAPVKPGMELTARSLIELMITRSDNTATDAMLKAVGGP -AEVTKWMRSKGFERFRIDRDIATLVRATGADQRDSTPPAEMVRLIAGLYKGEWLSGESTD -VVIGAMTRTVTGRRRMKAGLPSGIDFGHKTGTLNN-TASDVGFVEMPDGRVVVMAIYVTG -QG-GRPQRDARIAEITRTLYNGf ->[subseq from] Class A beta-lactamase n=1 Tax=Rathayibacter sp. Leaf296 TaxID=1736327 RepID=A0A0Q5B5B2_9MICO -------------------MGLVAVDSEDERTV-EHRADERFRFASSIKALAAGALLARTE ---PSDLERVVTW--SDVVDHSPVTGPATATGLPLGEVAEAAVRLSDNTAHNVVLQELGGP -AGLQEALRALGDDVTRVDRVEPELNRVSPE-GLDTGTARSLAADLRTLLLGDPLDSADRA -QLRDWMSGNATGDALVRASAPDGWSVLDKSGGAG-GLRNDLAVVERPGAAPIVIAVLTER -TDPTLPYDDALVARAASVALE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=M9UYD2_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAGLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora viridifaciens TaxID=1881 RepID=A0A1C4YTZ3_MICVI --------LDRLEAEFDARLGVYAVDTGSGRTV-AHRADERFAYCSTFKALAAAAVLDATS ---TAELDQIVRYSRADLLTYSSVTERHVDTGMTLRAVAEAAVRHSDNTAANLLLARLGGP -AGFQRVLRGLGDQVTEPARTEPELNAAVPGDVRDTSTPRALVGDLRAYAVDDALSAEDRA -VLVDWLKRNTTGGRSSGRVLPAGW------------------------------------ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Legionella donaldsonii TaxID=45060 RepID=A0A378JD83_9GAMM ---QLVKKIYDIEKRSNAVIGITAIHIEKNKVI-GHNGNKRFFMASTIKLPIAIAFLHLVD -QKKDSLNRVVNLGLNNVVPGSGTLHYLCERKMSLQQILKYMMANSDNSASDTLLQTVNGP -AYVTKRMHALGFKNIVINRSIIEMMMRFEKDPRDTTTPAEMAKLLVKIYKNEALSESSTK -VLMDIMEKCRTGRSRIRGLLPPYVKVAHKTGTWAFRFVSDVGIITLPNNGHIAIAVYVKS -RAVSNYTRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Renibacterium salmoninarum TaxID=1646 RepID=UPI0009B5CEB8 ----LDGKLTKLEQDAEITLAVCAS-VQGGQRL-EYRATEPLAMCSTFKAILVGVLLSKHA -RDDSYWATQVMIDPAKVLSYAPITQPFAGRPMPIADLCDATLRYSDNTAANLLLEQLGGP -PALTFFAADLGFKNTRLDRTEPDLNESKAGDARDTSTAADLAGIYSALLLGDALGALGQS -MLRGWMLRNTTSAQKMGAGIPKEAELADKTGSGSYGTLNDVGVIFRKAKPPVTLAILSRA -VSTDPNE---------------- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=Q2GBP5_NOVAD --qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKVAVAATFLEQVE -KGNFRLDQQFPMMVRVAETGRVSAEAPLRAGMTAQSLMELMITRSHNEATDGLIHAVGGY -ENVNRWLTRNGITGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGLPVGTLVAHKTGTLS-GVTDDVGIIRLPDGRHLAVAFFVTG -PEG-HAAHAALIARMTRVIYNGy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. HF-5092 TaxID=2594500 RepID=A0A553EKY8_9BACE --nKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVQECVIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKAYKD -FIYQTMVECQTGKDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSQIIADISRIVYKY- ->[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=A0A4Q5EDB0_BACUN --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides congonensis TaxID=1871006 RepID=UPI000934FAA8 ---SLETQLKKAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG -KHNQSLDTLLTIEKSDLKSYSPLRDKYPEGGMSIAELLKYTLQQSDNNACDILFHYQGGP -DSANKYIRSLGIQDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRREPLFAKEYRD -FIYQTMVECQTGQDRLVALLDKGVIVGHKTGTGDRNGCNDIGFVVLPDGHTYSIAVFVKD -SEESSPENSKIIADVSRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. C11 TaxID=2126991 RepID=UPI000D652A59 ---SLQQALDALAQRAPATLGVAVLDLSTGASA-HVNAGRDFPMMSMFKAPVAAAVLSRID -DGSMSLKQSVTITRDQVQGGSPSVGAHFRGEFTVEQLLKAAVTESDNTAVNALIRAVGGA -SVVTGYLHAHGINGMRVDMDEAGVAQAFLADPRNRSTPEAAIDFLHKLVKQELLSPASTQ -RLLAMMAAQTI-PNRLRAGLPANVRFADKTGTSARGAFNDIGIITWPNGHTVLVAAFLMD -SPMTDKARDALFADLARNVVS-- ->[subseq from] Beta-lactamase n=4 Tax=Francisella tularensis TaxID=263 RepID=A0A0E2ZP54_FRATU ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKTTPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase 1 n=1 Tax=Listeria grandensis FSL F6-0971 TaxID=1265819 RepID=W7BRK6_9LIST ------------------------------------------------------------- -------NKRIHFKKEDLIDHSPITEKHTEDGMTLKEIINAAMTYSDNTAANLMLHELGGP -KAYQKELVKIGDTVTQSDRYEPELNSAVPGDKRDTTTPEAMAKNLAFLVKKGNMPTDNFN -YFKQTLIDNTTGDKLIRAGVPEGYIVGDKTGSGSYGTRNDIAVIYPKDKKPLVWVIYSKK -DTEDAEYDDQLIADAAKVLSKYf ->[subseq from] Beta-lactamase n=2 Tax=Legionella worsleiensis TaxID=45076 RepID=A0A0W1AJI0_9GAMM ---EIAKKIAAIEKKSNAIIGISAIHIENNKVI-SHNSTQRFFMASTIKLPIAMAFLHRVD -QKKDSLNRIIKLGLSNAVPGSGSLHHACERKMSMQQILKYMLTDSDNSASDTILHTVNGP -EYVTKWMYELGFKNILINRSILEMFMRFEKDKRDTTTPDEMAKLLVKLYKKEALSASSSK -ILINIMEQCRTGRSRIKGLLPSHVKVAHKTGTWAPGFASDVGIITLPNKGHIAIAVYVKS -QAASDYSRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GR14_9BACT ---RLEKELLRLSNMSEGTVGICAVHIESGKTI-TQNGKDHFPMASSYKVAIATQLLSRVD -SGSLALNQLIPIVKTDFHPGSGMLPNSPATDLSVRSLLELMLLISDNSATDICLRLAGGP -AAVNACMKRIGVEGLRVDRPTAWLIAAFENDIRDTSTPEAMTLLLTKLYTQPVLKPASQA -LMLDIMKRCETGLARLKGALPPNTEVLHKTGTIGL-TASDVGIITLPDNGHVAISVFVKA -SKKEGAVRERTIAEVTRTIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000379CF86 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRDDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVCFLHRLATGQLLSASSTA -HLLEVMNRTTTFPDRLRSGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAXAITAAY--- ->[subseq from] Uncharacterized protein n=1 Tax=Flavobacteriaceae bacterium JJC TaxID=512012 RepID=A0A246AJW8_9FLAO --qNLKKEILKITKDKNATVAVSVNGIDFPYEFnNENADKKLPMLSVFKFHIAAAVLNEVD -HGKLKLDQKIPLKKSDLLEHSPLRDKYPNANLTVDEIIKYTVAQSDNNGCDILLRLIGGT -QTVQKFMDSKGIKNFQIKYNEEWMHKGKEYLYPNYTTVKSLSLLYKSFFEKKILSEKSTA -YLMNIMLGTTTGANKLKEQLPAGTAIAHKTGSSGKDAENDSGIITLPDGKHYAITVFVID -STESEAVNTKMISDISKKVWDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8NU28_9BACT ----LRAEIEKLIPRAGGGVGVAIKHIESGTEL-MINADEKYPMASAFKLPILVELFYQRA -AGKLSLDDRVEIAAGDLHVGSGSMSQLFDAPLSIRNLINLMMRISDNSAADILLNKA-GA -ANVSSRMRALGLETIRVDRTTQEMILEFSKVEKDVSSPRDMNILLEKIFRGEIVDRSTSD -EIIQILKQCQTGLTRIRGLLPQDTVVAHKTGTIG-GTTNDTGIVFLPRGDHLVITVFTKD -AKAPPAERERVIAEISRYAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. Leaf2 TaxID=1735670 RepID=A0A0Q4CBB3_9SPHN ------QQLAAVANASQGRIGVAAMDLATGRMV-DVLGDQRFPMASTSKVAIAATFLDGVD -KGKWTLSSEFPMMVPVPSASTAVAPVRAGEYMSAQRLIELMLTRSNNYATDALLRVVGGP -RAVNAWVERAGIEDWHIDRDIATLVRARVVDKRDSATPKAVVNLLAGIYQGKWLSPSSRA -VLLNTMGRCVTGKRRISAGVPAGVQVAHKTGSLNN-TSSDVGIIQTPDGRAFAVAIYVTG -QG-GRPGREARIASIARTIYNGy ->[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1IUJ0_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRN------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Legionella feeleii TaxID=453 RepID=A0A0W0TM57_9GAMM ---QLVKKIYDIEKRSNAVIGITAIHIEKNKVI-GHNGNKRFFMASTIKLPIALAFLHLVD -QKKDSLNRVVNLGLNNVVPGSGTLHYLCERKMSLQQILKYMMANSDNSASDTLLQTVNGP -AYVTKRMHALGFKNIVINRSIIEMMMRFEKDPRDTTTPAEMAKLLVKIYKNEALSESSTK -VLMDIMEKCRTGRSRIRGLLPPYVKVAHKTGTWAFRFVSDVGIITLPNNGHIAIAVYVKS -RAVSNYTRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0B6CRW7_9GAMM ---ALDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSVFKFLLVGAVLEYDM -QHEGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVTKLGDKDTIIKNDEPKINHTKPDSDINKTTPKAITQDINNLAFGNILDIKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -PSVKAPSNEKIIQQASKLSA--- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium contaminans TaxID=1423959 RepID=A0A1M6Z8T5_9FLAO ---EFKKNIEAILANKKADVGVSILTSGTKKEVtQINGNKPFPMLSTFKFPIALAVLHKVE -KGELSLQQKVYIKKEELLEYSPFREKYPEGNISLEDCIQWIVVYSDNNLTDVLLRMIGGP -DYVQNFINS---KDTVIKNDEKDMHKDWDSQFINTITPNEAIRLLEQFYNGKILNKEHTK -WLYTAMLNNVAGVKRLKGKLPKEVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD -TYETFENSEAIIADIAKTAYDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Burkholderia multivorans CF2 TaxID=985078 RepID=J5BJ40_9BURK ---RAQSELAALDKASDGRLGVAALDTSTGARI-AHHARERFPLCGTYAVVAAAAILARAS -LDASLLPRRILYRRYGIVAGSPVTESHADTGMTVAQLCAAMLESGDKGAGNLLMDVLGGP -QAVTAFARESGDTTFRLDRWEPELNTVGPDDVRDTSTPVAMVDTLQRLLLGDALREPQRA -QLIDWMTAGAR-GDGIAAAVPPGWRVAAKRG----------------------------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A414GNX3_9BACE --sKLETKLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A6C1QMN7_9BACT --hDLRESINQIISSKNALTGVAIAGHDGKDTL-SLNGNLQFPMQSVFKFHIALAMMAEID -KGNFSPEQKVRIKKDDLLPYSPLRDKHPEGALTIAELSKYAVALSDNVASDALLRLLGGP -LRVECFFADNGFADISIKINEEEMQSNWDLQFKNWTTPMASNQILRAFFEDHLLSQASHE -FIWRIMGETITGRNRIRGKLPHSTDVAHKTGWSGTAAVNNIGIVFLPDDSHFYISVFVTD -SKEDFQTNEQIIADIAKAAWDYf ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas acidophila TaxID=1912599 RepID=A0A1I9RH04_9PSED -hdALQKTLDRFASAAPGTLGVAVLDMQGSTGW-QVNGNQAFPMMSVFKAPLGAAVLDRVD -KGELKLNQRVTITRDELRPRSAIRGAFQGDRFPLADLLHAAISESDNTGADALLRLIGGP -QAVTAYLRAHGIHGMTVDMGEGQVADAYLSDPRNRTTPAAAADFLRKLSTGALLSPTSTQ -YLMTLLNEQVT-PRRLRVGLPAGVTFADKCGTSLTAAFNDIGIITWPDGHRVIVAAFLMA -SHASREERDRLFADLARAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPR3_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIKKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD -FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF18_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIKKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD -FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=4 Tax=Francisella tularensis TaxID=263 RepID=A0A0B3VPP7_FRATU ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKITPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. Cy-637 TaxID=2608327 RepID=UPI00141E1847 -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. Ery1 TaxID=2306995 RepID=A0A418NL45_9SPHN ----FERQIVRLADGANGRIGVAVLDLATGQEF-SVLGDQRFPMASTSKIAIAATYMEGVE -QGRWSLSSEFPLLIPVRSEFSTVKAPVRRGKLPASQLIELMITRSSNSATDALLAAVGGP -GAVNDWMRRAGIEEFQLTRDIATLVRARAVDLRDSATPRAMTELLAGLYQGRWLSKSSRQ -VILGAMERCITGKRRIPALLPAGASVAHKTGSLNN-TSSDIGIVHTPDGKAFAVAIYVTG -QGAR-LAREHKIAQIARAVYSGy ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter endophyticus TaxID=1808508 RepID=UPI00135D97E5 ---DFERTVANLAAGDKGRIGVAALDLSSGKEI-AILGDQRFPMASTSKIAIAATFLEGVD -QGRWSLTSEYPLMVPQRSQSSATAPVHKGSYLPASQLLNLMLTRSSNSATDALLAVVGGP -DAVNAWAKRAGIGEFELTRDIATLVRAAHIDHRDSATPRAMVQLLTGLYQGRWLSSESRN -LLINTMEECRTGKRRIVADMPSSVTVAHKTGSLHN-TSSDIGLLTTPDGRTIAVAIYVTG -QG-SRLNRERRIASIARAVYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella sp. CPCC 101087 TaxID=2497754 RepID=UPI00101CA34C ----LDTRIRQLAQGFDGDVGIAVRDVESGWTT-SWNGTRHFPQQSVSKFWVALTAFQRVD -AGELDLSQRVTLRREDLTLHQPIASQIGSNGTTLGDLLFRALTQSDNTANDAVLRRAGGP -EAVRAMLARKGIQGVRFGPGERLMQSSYVEDPIDGATPEGLVEGLARLQRGELLSRASTE -RMLSIMSQTRTGRQRLTGGLAPGWRIAHKTGTGQQTGYNDIGILTSPEGRHYAVAVMIGR -TSVPIPRRMELMQDVTRAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235) TaxID=288705 RepID=A9WLK3_RENSM ------GKLTKLEQDAEITLAVCAS-VQGGQRL-EYRATEPLAMCSTFKAILVGVLLSKHA -RDDSYWATQVMIDPAKVLSYAPITQPFAGRPMPIADLCDATLRYSDNTAANLLLEQLGGP -PALTFFAADLGFKNTRLDRTEPDLNESKAGDARDTSTAADLAGIYSALLLGDALGALGQS -MLRGWMLRNTTSAQKMGAGIPKEAELADKTGSGSYGTLNDVGVIFRKAKPPVTLAILSRA -VSTDPNE---------------- ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. BPTF-M16 TaxID=2169535 RepID=A0A411ZEV6_9SPHN ---SFERRIAQLADGSRGRIGVAAIDLNTGDEV-AVLGDQLFPMASTSKIAVAAAYLELVE -QGKYSLTSEFPLLIPVRSASSRAAPVREG-NMSAEDLIEIMIARSSNPATDALLRVVGGP -EAVNDWMRRQGIDEFSIDRDIATLVRSMHIDTRDAATPKAMIELLQGLYRGDFLTAESRQ -VILDAMAKTRTGKRRIRAGMPDYVGVMHKTGSLNN-TSSDIGIIEGPNGHAIAVAIYVTG -QGA-RSAREARIANIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter dongtanensis TaxID=692370 RepID=A0A1B2A9D4_9SPHN ----LSKTVAQIADGSAGRIGVYAVDLATGREV-SVLGDQRFPMASTSKIAIAATFLEGVE -KGRWSLTSEFPLMVPVASPSSSKAPVRPGQYMKAIDLIEIMITRSSNPATDALLAVVGGP -AAVNNWASRNGISDFNITRDIATLVRAQRIDVRDSATPQAMVQLLAGLYQGKFLKESSRN -VILGAMERCRTGTRRIPGMLPDGARVAHKTGTLSN-TASDIGIIHTPDGRAIAVAIYVTG -QG-SKPARDAKIASIARALYDGy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A139LHC4_BACOV --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SN54_9BACT --dDLKNNILTIIDSKKATVGVALI-VDGKDTL-TINNEIHYPMQSVYKFHLALAVLNYMN -LNKMPFDIPVYIKKSDLLPHSPLRDDHPEGEMPVTEVLQYTVSKSDNNGCDILFRLLGGP -KEVDRYIKSLGISEVNIAATEEEMHSGWEVQFWNWTTPLATVELLEKFRTGDVLPMPYHD -FLWKTMVETSTGANKIKALLPEGTIVAHKTGSSFRNAENDIAVVQLPDGRYYSLAIFVSD -SKESDETNCRIIAEISKAIYDH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera intermedia TaxID=61648 RepID=B2CD66_KLUIN --------------------------------------------------LLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWYFAD-------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=bacterium (candidate division B38) B3_B38 TaxID=2012999 RepID=A0A532UBV2_9BACT ----LQSQIEKVIHRVDGVVGVAIKHLESGEEV-KINGDTLFPMASTFKVPIMVEVFHQIN -EGKFGLDDEAEMTETDLHLGSGMLSSLQAPGLSIRNFITLMMIISDNSAADFLLQKV-GV -DNVNHRMEALGLTDIHIDRTCHQLIMLFNREAKDVCSPADMNSLLEKIFKAEMLDRETCD -LMLQIMLRCQTGEKRLRGILPRGTRVAHKTGTIVT-TVNDCGIIYLPNRGHIVITVFSKE -VEDETADMEKVIAEVARFAFDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=A0A3S3QYR9_RHIML ---RLRLELETLADAHPGRVGICVQD-QPKSPV-CVNGAQRFSLQSVMKLVVAAAVMQAVD -EQRIRLDDQITIRREDLSVIQPIADIVARHGTSVRDLVRRAVVASDSAATDVLIARLGGT -KAIQVFLEMAGLTGVRIDRTERELQTAYIKDPRDTATPRGMAAFLYSLASGSLLTAGSTE -FLLTVMSQTTTFPDRLRAGIPPEWGIGHKTGTSQNGVTNDVGILTAPDGRRIAVAAFVAE -SRAGQAERAAVIAAAARAITAAy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPM3_9BACT --kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEDLMNRDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD -FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSNKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter gaetbuli TaxID=266952 RepID=UPI0013619911 --nAFEQRLAELADGSNGRIGVAAIDLTSGQMV-TVLGDQRFPMASTSKIAVAATFLEGVE -KGKWSLTSEFPLLLPRKSASSKVAPVYEGEYMKAIDLIEIMITRSSNPATDALLRVVGGP -DAVNDWVRRQGIRDFSIDRDIATLVRAQHIDKRDSATPKAMLDLLSGLYQGKFLKPESRR -VLLGAMSRTRTGKRRIPALMPESVRVSHKTGSLNN-TSSDVGILETPDGRAVAVAIYVTG -QG-SRLNREAKIAQIARAIHDGy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. MBES04 TaxID=1206458 RepID=A0A0S6WVK6_9SPHN ----FERQLAAAAEASNGRIGVAAVDLRTGRTL-DVLGDQRFPMASTSKIAIAATFLEGVD -KGKWTLTSEFPMLIPVSSKSSAVAPVREGQYLTAAKLLELMLTRSNNYATDGLLRVVGGP -DAVNAWVRRAGIEDWHLDRDIATLVRANVIDKRDSATPMAMVTLLRGLYEGQWLSKRSRD -TLIAIMGRCVTGRRRIPAGIPDGAMIHHKTGSLHN-TSSDVGIVETPNGDVFAVAIYVTG -QG-SRPNREARIASIARTVYNGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides stercorirosoris TaxID=871324 RepID=UPI001114E074 --kELEQQIGQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRNISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEDLMHQDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD -FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0F7LFU0_ECOLX ----------------------------------------------------AAAVLKESE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Francisella philomiragia TaxID=28110 RepID=A0A0E1N7H4_9GAMM ---TIDDSFNNLEDKYHGKLGIYTVNTDDKINI-SYNENYHFPICSVFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTISQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSSINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGYAATNDVAIIWPQNKPPFALSILYTN -PSVKAPSNEKIIQQASKLTAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercorirosoris TaxID=871324 RepID=A0A1M6H4V1_9BACE --kELEQQIGQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRNISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEDLMHQDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD -FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0007060969 ---QLDDSFKNLENKYDGKIGIYTLNTNDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKITPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. AAP93 TaxID=1523427 RepID=A0A0N0KB86_9SPHN ---AIEQQVSAIVAQGRGRIGVAAVDLDGGGQI-MINGDMPFPMASTAKIAVAATYLSGVE -QGRLRLDQQFPMMVPVAEARGTVAAVRPGMVMSAQSLMELSITRSDNHATDGLIAAVGGI -GAVNTWLNRIGVTGQHLDHTMATLVRVTTIDTRTSSTPRAMVQLLAAIDRGGALSPESRA -VLLDTMTRTSTGKNRIRSGLPEGVVFAHKTGTLA-GVTDDVGIVRLPDGRHLAIAIFVTG -PEG-HTAHAGLIAQIARVLYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonadaceae bacterium KCTC 52780 TaxID=2172047 RepID=UPI000E0D3003 ----LDARIRQLGQSFDGHVGIAVRDVATGRTS-SWNGDRYFPQQSVSKFWVAIAALQRVD -AGQLDLSQRVTLTRNDLTLHQPIATQIGTGSTTIGELMFRAITQSDNTCNDFVLRRAGGP -EAVREMLTRNQLNGVRFGPGERLMQSAYVEDPIDGATPEGIVEGLARLQRGELLSRASTE -RLLSIMSQTRTGRQRLTGGLAPGWRIAHKTGTGQQAGYNDIGIITAPDGRHYAVAVMMGR -TSVPIVQRMEFMQDVTRAVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Francisella novicida TaxID=264 RepID=A0A2L1CI97_FRANO ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNVGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEVNYTQPHSNINKTTPKTITKDIYKLAFGDILDKKHKD -IFTKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNTPSNEEIIQQAAKLIAN-- ->[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C801966 ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMITVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD -RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium multivorum TaxID=28454 RepID=UPI00129C626C --nNLRKELHQIISTKNATVGISMKGIEDKDTL-SINGHLNAPLMSVFKFHIALATLDLVD -KGKLSLSQKFFIKKEDLHAWSPIRDEFPNGNLTLDQLLRYTVSHSDNNGCDILLDLIGGP -ETVQKFIHKQGIKDFTIKVNEQEMR-IWENLYINTTTPLASTELLEKFYAGQVLKKNTTN -YLYQLMVECSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIFKLPNGNHIVLSVYLKD -ITEEREVTEKIIADITKSIWNYy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. BW1 TaxID=2592621 RepID=A0A5D0WZG0_9SPHN ----FERQLAAAAEASNGRIGVAAVDLRTGRTL-DILGDQRFPMASTSKIAIAATFLEGVD -KGKWTLTSEFPMLIPVSSKSSAVAPVREGQYLTAAKLLELMLTRSNNYATDGLLRVVGGP -DAVNAWVRRAGIEDWHLDRDIATLVRANVIDKRDSATPMAMVTLLRGLYEGQWLSKRSRD -TLIAIMGRCVTGRRRIPAGIPDGAMIHHKTGSLHN-TSSDVGIVETPNGDVFAVAIYVTG -QG-SRPNREARIASIARTVYNGy ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2Q8I6_9CYAN ---RLQRKLEAVAKGSDGRVGICAEEMKSGAIA-CVNGDQRFSLQSVMKLVVGAAAMDAID -RGQMRLEDVITVRKKDLSLVQPIADLVAERGTTVADLISRAITESDSAATDLLFARVGGA -EGIQTFLKTKKISGLRVDRDEKHLQTAYLKDERDTATPRGMVTFLSALASGKLLSAKSTA -YLLKVMQRTVTFPDRLKAGVPKGWTLGHKTGTSLTAVTNDVGILTAPDGGTISVAVFVAE -SRRSSKERAKVIAATAKTITSSy ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000C999CC6 ------ATVQKLAHSLEARVGMAAVMLDTGETV-SIGDEAAYPMQSVFKFILALSVLKQVD -EGKLDLEQIIHIRPEQLLKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -GTVQKDLKEWGISGINVRFTENEMLRNHDLQYVNSSRPSAMNALLRAFDEGKILNKGTQR -FLWDIMAGCSTGATRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSLPACEKVIASMARWLCTEw ->[subseq from] Uncharacterized protein n=2 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=I9JMQ7_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIIGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQVNNKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Dyella jiangningensis TaxID=1379159 RepID=A0A328PCE8_9GAMM ----LQQALDVAVRARPGTLGVAVLDMGSGARA-GVHTDEAFPMMSVFKAPVAAAVLAQVE -EGSLSLEQEVTLARTDLRDGSAVPQLAAGKTFTIGRLLRGAVSESDNTAVDALLRVLGGP -QKVTAFLQAHGLKGMRVDLGEGGVNEAFLADPRNRSTPAAAVEFLRKLQGGELLSPASTQ -RLQHLMAEQTL-PNRLRAGVPQGVRFAGKSGTSGTQAYNDIGILTWPDGQAVIVAAFLSD -SAMPAPQRDALFADLARAVAR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPU7_9BACT --sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISLSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=3 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A095H6B9_BURGA -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. MBES04 TaxID=1206458 RepID=UPI000A01D41C ----FERQLAAAAEASNGRIGVAAVDLRTGRTL-DVLGDQRFPMASTSKIAIAATFLEGVD -KGKWTLTSEFPMLIPVSSKSSAVAPVREGQYLTAAKLLELMLTRSNNYATDGLLRVVGGP -DAVNAWVRRAGIEDWHLDRDIATLVRANVIDKRDSATPMAMVTLLRGLYEGQWLSKRSRD -TLIAIMGRCVTGRRRIPAGIPDGAMIHHKTGSLHN-TSSDVGIVETPNGDVFAVAIYVTG -QG-SRPNREARIASIARTVYNGy ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000626EE9A -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter marinus TaxID=874156 RepID=A0A0H0XTD6_9SPHN --nALEARIAQLANGSEGRIGVAAVDLATGQTI-SVLGDQRFPMASTSKIAIAATYLEGVE -QGRWSLTSEFPLLWAVRSRFSTNAAPVRRGEMTALQLIDIMITRSSNPATDALLAAVGGP -AAVNDWARRAGLRDFSLDRDIATLVRASHIDVRDSASPETMVQLLAGIYQGRWLNSASRE -VIIDAMERCRTGTRRIPALMPDNVTVAHKTGSLNN-TSSDIGILTGPDGRSIAVAIYVTG -QG-SRLNRERRIASIARGIYDGy ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000F805CBD -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A3E4R3J8_BACUN --sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQNISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WRM6_9BACT ---DLTALIEKTAGPAKGRVGVFAVVLETGDSV-SLDPDGRYPMQSVYKFPISMVVLRQVE -EGKLKLDQKVRVEKEEYVRRSPLRDKNPNGAVTVQELIRLSIVESDGSASDALMRLAGGA -AAIQEYLTGINVGEVIVANPEKEIGQDWETQYRNWATPEGAASLLRALYEKRGISDQHQK -LLLKFMTESVPGAKRLRGMLPPGTAVAHKTGTSGTAATNDIGIITLPNGNHLAIAVFVSD -SPADETTRESVIAGIAKAAWDTw ->[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Leaf344 TaxID=1736346 RepID=A0A0Q6KHF4_9BRAD ---RLDREIAALEQRSQGRLGVALLDLRDRELW-SHRGAESFPMQSVFKLPLAIAVLQAVE -AGRLKLDQPITIHRREFSLHSPLAKAFKGESYPVRELIRLAAGESDNTAADILMREIGGP -KTVTAMLKAGDIAGISVDRYEREFQPAALKDKRDASTPEASVLFLEAQAKGNWLRDPAHS -RLIDIATDSPTGPKRIKAGLPSGARFAHKTGLGLNHATNDIGVVRLPDGRAFAIAVYLAG -SRADEATREATHAAMARLAVA-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides gallinarum TaxID=376806 RepID=UPI0003A1516F --qALKERIAGFLKEKKATVGVAVLADGDETVL-QHNDRVRYPLLSVFKFHVALAVLDKMN -RQDTALDSIVHVKASQLHPYSPLRKKYAGQDISLKELLQYSISQSDNNACDILIEYAGGI -GHIHEYIKGLGISGFNLSETEDSMHRDPQRTYLNWNTPSEMVRLLKIAYEKTLFAPRYKD -FLWKIMAETSTGSNKLKGLLPSGVTVGHKTGSSDRTADNDAGVVIMPDGRKYYIAVFVMD -SSETDEENAAIIARISRMIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. RIFCSPHIGHO2_12_FULL_65_19 TaxID=1802172 RepID=A0A1G3KM02_9SPHN ----LSDRIRELWRTFPGKTGIAVQRIDGEWTL-SERGGELFPQQSVSKFWVALTVLDAVD -QGRLSLDQRVRIGPEDLTLYQPLAARVRSQGMTVRELIETAITHSDNTANDSLLRTVGGP -AAVRAFIAKKDLGAIRFGPGERLLQSNYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQDVMSRTRSGPRRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS -TTAGIPARMALMQAVSSAVAEY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SNM6_9BACT --sELENRIDSLLNRKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium resinovorum TaxID=158500 RepID=A0A031JS27_9SPHN ------QQLAAVANASQGRIGVAAMDLSSGRMV-DVLGDQRFPMASTSKIAIAATFLEGVD -KGKWSLSSEFPLMVPVGSASSAIAPVRPGEYMSATRLIELMITRSNNYATDALLKVIGGP -KAVNAWIQRAGIDDWHIDRDIATLVRARVVDKRDSATPKAMVNLLSGIYQGKWLSPSSRN -VLLGAMSRCLTGKRRIPAGLPAGVEVSHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG -QG-GRPGRETRIANIARTIYNGy ->[subseq from] class A beta-lactamase n=1 Tax=Empedobacter falsenii TaxID=343874 RepID=UPI00056E3E61 --eSLRTEINQILSSKNLTAGISLKNIENKDTL-SINGNQMMPMMSVFKFHIALAVLHEVD -QNKLQLNQRFFIKKEDLLPWSPILEDYPEGILTLDQLLRYTVSHSDNNGCDILLKIIGGT -KTVQNFINKQGIKDFIIKVNEQEMQT-WDNLYLNTTSANATTKLLEKFYATKVLKKNSTT -YLYQLMVETSRGLTWMKAGLPENTELAHRTGISDRVAMNDIGIIKPINHQPIILSIYLKN -ITEERTETEKVITDITKAVWNYy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. FSW06-99 TaxID=1739113 RepID=A0A117V3C0_9SPHN ---AIQQNVEAIIARGRGRIGVAAADLDGGGQV-LIHGDMPFPMASTVKIAVAGTFLSGVE -AGRFRLDQSFPMMMPVAAREHGEARLRPGPVMSAQQLMELMITRSDNHATDGLITAVGGV -GAVNAWLAKVGIVGQHLDNTIATMVRATTIDTRNASTPRAMLALLAAIDRGGALSPQSRA -VLLDTMTRTSTGKNRMRAGLPEGTVFAHKTGTLQ-GVTDDVGIIRLPDGRHLALAVFITG -PEG-HTPHASMIAQITRALYDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=B2ZTR1_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPFEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDSVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAESSRTNEAIIAQ--------- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A258V622_9SPHN ----IQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE -KGNYSLDQQFPMMLRVVEKASPEAPLRAGSVMTAQSLMELMITRSSNEATDGLIKVVGGY -ENVNRWLTRNGITGQRLDHTMATLVRARVIDTRTSSTPRSMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLS-GVTDDVGIVRLPDGRHLAVAFFVTG -PEG-HAAHAKLIARMMRTIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter sp. Alg231-14 TaxID=1922225 RepID=UPI000D54E482 --------LRIIEAQMGGALGVELFDTQTGLSI-GLNSGMRFGHCSSFKLSLAALVLARNA -AGADDADRIVTWEESDLMFVSPFTTERLNEGASLRELAEFTQKYSDNAAANILLREVGGP -AALTAFWRSIGDGTSRLDRIEPHLNNVPSTEIRDTTTPSVMARTVAKLIYGDVLPDAEKA -TLRQWMVDTSTGTRRVRAGLPGDWRAGDKTGTSIGSLYVDIGFVENPSRGPITFATYLRM -PNESDPAAEAALAQVGEVLT--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SIY2_9BACT --sELENRIDSLLNRKKATIGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. QXT-31 TaxID=1357916 RepID=A0A1P8WZ37_9SPHN ----LDDRLFEIWKAFPGKTGIAVQRIDGEWTL-TQRGNELFPQQSVSKLWVTLAVLDAVD -NGRLRLDQNVRIGPEDLTLHQPIAARVQSQGMTVRELIETAITQSDNTANDSLLRTVGGP -DAVRRFIDKKDLGAIRFGPGERLLQAAYRADPPDGASPAAIANALTKLARGNLLSPESTQ -YLLGVMTRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVLMGE -ASSPVPARMATMQSVSRAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI00119D7130 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KGFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE -LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercorirosoris TaxID=871324 RepID=A0A413H2G9_9BACE --kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEELMHRDVATQYQNWSTPEAVVRLLNIADKQTLFATGYKD -FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519KIB8_9CAUL -------DLSALEARNGGRLGVCIQG--DAGAV-QWRPDERFLYCSTFKLFLAAATLQRVM -QGEEQFDRQVPVIATDLLPHAPMTESAVGGTLSIRDLCRAAVEFSDNPAANILIRELGGL -DALRAWYRSKGDTFTSIDRLEPQLNRL--DGDKDTTSPAQTVRNLGAILTGT-LSGLEFK -SLMGWLQASPTGPNRIKAGVPAGWTVWHKTGTGAAGPTNDIGYLIDPDVGQFMIAVYYDA -PVVPIPEQETIIAEATRIALK-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sediminis TaxID=707214 RepID=A0A512AIB5_9SPHN ---AIESQVSAIVAQGRGRIGVAAVDLDGGGQI-MINGDMPFPMASTAKIAVAATYLSGVE -QGRLRLDQQFPMMMPVAESRGSVAAVRPGVVMTAQSLMERSITRSDNHATDGLIAAVGGI -GAVNTWLSRTGISGQHLDHTMATLVRATTIDTRTSSTPRAMVQLLAAIDRGNALSPESRA -VLLDTMTRTSTGRNRIRSGLPEGVVFAHKTGTLS-GVTDDVGIVRLPDGRHLAIAIFVTG -PEG-HTAHAGMIAQIARVLYDGy ->[subseq from] Beta-lactamase class A n=1 Tax=Moheibacter sediminis TaxID=1434700 RepID=A0A1W2BUY7_9FLAO ---NLRNEINQLISSKNLTAGISIKGIEVKDTL-SVNGNLSMPMMSVFKFHIALAVLNEVD -KGKLKLNQKIFVKKEELLSWSPIREEFPQGNLTLDQLLRYTVSHSDNNGCDILLRLIGGT -ETVQKFINLQGIKDFTIKVNEEEMS-NWDNLYLNTTSPLASTELLEKFYKGEILKKKTTK -YLYQIMVETSRGLTWMKAGLPEGTELAHRTGISNTNAMNNIGIVKLPNGKHYILSIYLTE -IMEEREVTEKILADIAKATYNYf ->[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. DS-208 TaxID=1339276 RepID=A0A015VGH3_BACFG ----LKTQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNKNLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNACNDIGFILLPSGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AKZ9_ECOLX -------------------------------------------------VMAAAAVLKQSX -XQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] Beta-lactamase n=5 Tax=Bacteroides TaxID=816 RepID=E0WMY1_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C800526 ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD -RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] Beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=A0A2S4NDN2_BURGA -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLAE -QGRLPLGQRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -AVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLQDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C802E56 ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD -RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] Beta-lactamase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=G6FVR1_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD -RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C7FF3BA ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD -RILDIMRNTVR-NHLLPTGLEQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] TLL2115 PROTEIN n=1 Tax=Synechococcus elongatus TaxID=32046 RepID=UPI000181CD1C ---NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD -EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA -AELNQQFQEWGLENTVINNPEPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMVYQAf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A415K6Q4_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -ETVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QI98_9SPHN ----FERRIAELADGSSGRIGVAAIDLTTGQEI-AVLGDQRFPLASTSKIAIAATFLEGVE -QGRWSLRSEFPLLWARKSASSPVAPVAEGERMRASELIEIMITRSSNPATDALLRAVGGP -NAVNSWMRRNGMSEFNIDRDIATLVRAHHIDRRDSATPGEMLELLTGLYQGKFLSSESRR -VILGAMSRTRTGTRRIPAMMPASVRVSHKTGSLNN-TSSDVGFLEMPDGRTVALAIYVTG -QG-SRPAREAKIAAIARAIHDGy ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. HII-3 TaxID=2075565 RepID=UPI000CDA5B89 ------QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGDQRFPMASTSKIAIAATFLEGVD -NGKWSLSSEFPLLVPVASRSSAIAPVRPGEYMSAARLIELMITRSNNYATDALLKVVGGP -KAVNAWVERAGIEDWHIDRDIATLVRAKVVDKRDSATPKAMVKMLAGIYQGKWLSPSSRR -VLLGAMSRCLTGKRRIPAGVPAGVQVSHKTGSLNN-TSSDVGIIETPDGRVFAVAIYVTG -QG-GRPGRESRIASIARTIYNGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes senegalensis TaxID=1288121 RepID=UPI00101C5688 --eSLERALRAVTDSVRATVGVAVV-FGDGDTL-AVNGGRCYPMLSVCKFHQALAVLDRLD -RRGLPLTTRIPVRRSDLLPWSPLREACPGGGFTVAELLTYSVAQSDNNVCDVLFRFLGGT -EAVDRYIAGLGIGETVIVADEEMMHRHTDNQYLNRTTPLAAVRLLERFRRGELLSAAYGD -FLLETMFATGTGPDKLRGLLPADVAVAHKTGSSDRDADNDIGIVRLPDGRSYSIVVFVMD -SREDDRTNAAVIARISRLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A412E227_BACSE --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIRKLGINDFNLSETEDSMHWNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD -FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVVIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] Beta-lactamase n=1 Tax=Legionella feeleii TaxID=453 RepID=A0A378IY02_9GAMM ---QLVKKIYDIEKRSNAVIGITAIHIEKNKVI-GHNGNKRFFMASTIKLPIALAFLHLVD -QKKDSLNRVVNLGLNNVVPGSGTLHYLCERKMSLQQILKYMMANSDNSASDTLLQTVNGP -TYVTKRMHALGFKNIVINRSIIEMMMRFEKDPRDTTTPAEMAKLLVKIYKNEALSESSTK -VLMDIMEKCRTGRSRIRGLLPPYVKVAHKTGTWAFRFVSDVGIITLPNNGHIAIAVYVKS -RAVSNYTRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2E2IVJ2_9SPHN ---SFEQRIAELADGDRGRIGVAALDLTTGEQV-AVLGDQLFPMASTSKIAIAATYLEMVE -QGRYSLTSEFPLLIAVRSPSSPAAPVREGNYMQAIDLIEIMITRSSNPATDALLAAVGGP -EKVNDWMRRQGINDFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLHRGDFLSDQSRR -VLLGAMSRTVTGRRRIPANMPAEARVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG -QG-SRLNREARIASIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUN6_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQISHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQGSDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A222UA54_ECOLX ------------------------------------------------------------- ----NLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAI----------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Croceibacterium ferulae TaxID=1854641 RepID=UPI000EB236C5 ----LQQQIANMADGGRGRIGLFAVDLASGEEI-AVLGDQRFPMASTSKIAIAATFMEGVE -RGRWSLSSEFPLMLPVASRSSAVAPVRAGEHLSARQLIELMITRSSNPATDALLKAVGGP -AAVNDWVHRAGIREFNLSRDIATLVRAASIDTRDSATPRAMVELLAGLHQGRWLSDSSRQ -VILGAMERCRTGTRRMRALLPTGVTVAHKTGTLNN-TASDIGFIKAPDGRTIAVAIYVTG -QG-GRPARDAKIANLARAIYDGy ->[subseq from] Beta-lactamase n=2 Tax=Rhodospirillales TaxID=204441 RepID=A0A1E4LHS4_9PROT ---RAEAEIARIAGFAEGAVGLAARHLGSGLAL-GHRADEGFPMASTVKVPLALAVLELVD -AGKLQLDQMVAVDPLEMNPSAPIGEEFLYPGLSLLNLLEPMITRSDNTATDVLFRLAGGP -AAVAAYLARLGVAGITPSRSVRDLLIAYSSDPRDQATPAGMVELLARLFHAEGISRAARD -TLLPIMGRTSTGLRRIEGRLPKGVAVANKTGSAS-GTTNDVGIVTLPGRGAVAMAVYVKD -SALPPAEREDVIADVARTAYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Brevundimonas diminuta TaxID=293 RepID=A0A3D4DDP1_BREDI -------DLSALEARHGGRLGVSAAT--EGRSA-AWRGYERFVYCSTFKMYLAAATLLRVQ -AGQERLDRAIPVTQADMISHAPVTEPAVX-------------EVSDNPAANILIREMGGL -EALRSFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPADWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8I0L6_9BACT ------SAVQELAHSLKARVGMAAEMLDTGETV-AVGDEADYPMQSVVKFVLALSVLKRVD -QGVMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEDEIHRNRDLQYANSSRPSAMNSLLRAFDEGKILKKGTQR -VLWDIMAGCSTGHERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRMIASMARWLCMEw ->[subseq from] class A beta-lactamase n=1 Tax=Chakrabartia godavariana TaxID=2056873 RepID=UPI0010FAD5A8 ----MVAALRAIWSAFPGKAGIAVMKTDGSWMV-SYRGDEPMPQQSVSKLWVAIAVMDAVD -KGQLSLDDQVTLKKSDITLHQPIAGLIGPNGTTIANLLKRAMTQSDNTANDFLMRRVGGP -TAIRELIASKRLGAIRFGPGERHFQARYVADPMDGATPAAIARSLARLKRGELLSAQSTR -YLLNVMESTETGRARLKAGLPAGWKLAHKTGTGQTAGFNDVGIMIAPDGTSYAVAVMIAD -TTAPVPTRQKLIQQVAITVAA-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPQ7_9BACT --kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEDLMHRDVATQYQNWSTPEAVVRLLNIADKQTLFAAGYKD -FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI001410066B ---RLEQELIRLSDISGGKVGICAVHLESGKTI-SQNGKDHFPMASSYKVAIATQLLTRVD -SGSITLDQLIPITKNDLHPGSGMLS-----SLSVRSLLELMLLISDNSATDVCLRLAGGP -DAVNGCMKRLGIDGLQVNRPTAWLIAAFENDIRDTSTPEAMTLLLSKLYMQSVLKPDSKA -LILDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPDKGHVAISVFVKS -SKKDGALRERAIAEVTRTIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TCM1 TaxID=453246 RepID=A0A196M7M5_9SPHN ---KLLAEFARFATLSDGSVGIAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD -AGELRLDDQLALDPALASEGIAWMFSRPGASLSVDRLLELMLQKSDNNATDVLVARAGGP -QAITGFVAKLGVNGLRVDSDTAHLLYNFAMDPKDTSTPSAMLDLITAYASGRALSAASTQ -RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVAVFVMK -DSKGHRSRDRIIAEAARAAYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides fragilis CL05T12C13 TaxID=997881 RepID=I9VY34_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADCMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTIGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A412VKU6_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHKDLNLCYQNWTTPLAAAELLEIFHKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI0004528402 ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q45116_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Nitratireductor aquibiodomus RA22 TaxID=1189611 RepID=I5C6Q8_9RHIZ ---TLSQTVERIESTLGARVGIVIRDTGSDWRW-SHRAEERFLMNSTVKALICGGVLAELD -KGMLTLDQTLPIRQFDIVSYSPVTQKHVGKAMSIADLCLATLDISDNAAANLLIGRLGGP -KAVTAFLRSIGDPVSRLDRLEPKLNAFAPGDPRDTTTPAAMTETWHALLLGDVLKPASRT -QLIEWMSH---------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter troitsensis TaxID=292222 RepID=UPI00070A2B8C ----LEATVAQIANGSAGRIGVYAVDLASGREV-SVLGNQRFPMASTSKIAIAATFLEGVE -KGRWSLTSEFPLMVPVASPFSGSKAPRPGQYMKAIDLIEIMITRSSNPATDALLAVVGGP -AAVNNWASRNGITDFNITRDIATLVRAHRIDVRDSATPQAMVQLLAGLYQGKFLKESSRK -VILGAMERCRTGTRRIPGMLPDGARVAHKTGTLSN-TASDIGIIHTPDGRAIAVAIYVTG -QG-SKPARDAKIASIARALYDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346TJ63_KLEPN ------------------------------------------------------------- ------------------------------GTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLA---------- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Parabacteroides goldsteinii TaxID=328812 RepID=UPI00101CD657 --eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TINNEDRYPMMSVFKFHQALAVLNYLQ -QNNLPLDTPIRIEKEDIIEYSPLRDKYPQGNLPINELLKYIIQLSDNIACDVLFKYIGGP -SVADKYIRSLGIQQFSIVITEDDMHQDLSACYLNWSTPLEAARLLEILLTRSLFKDEYQE -FLKNIMIECETGKDRLPQLLKTDAVIGHKTGTSDQNGTNDIGFVLLPNGSRYTVAVFIKD -SNESMETNAKIISSISEVIYKYf ->[subseq from] Serine hydrolase n=1 Tax=Deltaproteobacteria bacterium HGW-Deltaproteobacteria-21 TaxID=2013749 RepID=A0A2N2GZ94_9DELT ---RLRSRVESAIPPSQGVVGVSIKHMESGIVL-AVHGDEPFPMASTFKLPLLVELYAKEK -EGAFKWDDLVEISSTDQHLSSGLTALYDTPGLSIRNLANLMIIASDNSAADICLSKVGGP -SKVTAGMRKLGIEGIRIDRSCQELILRLAADPADSATPDAMVALLERIWQGRAVDPAASD -AMMKTLNRCRTGANRIRGLLPPSTDVAHKTGTLG-GVVNDVGIIALPDNGHVAIAVMCKR -TRAPRDQVERVIADIARYAYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Syntrophus gentianae TaxID=43775 RepID=A0A1H7VZG4_9DELT ----LEGEIKRLAAMAGGTVGVSALHIESGQLF-SFHGGVRFPMASAYKIPIAVQLLRRVD -QGEIRLNSIVTLTSHDIHPGSGKLIKTFKKKYSVRELLELMLLVSDNSASDAILKLAGGP -EAVTRAMKDLGIEDITVSRSTLNMLARFYTDLRDTATPDAMTSLLAMIYDGTVLQPETTS -VLLKIMERCQTGNSRIKGLMPPGMTVANKTGTIGPGMVNDVAILTLPEGGHVALTIFIKI -SNRSVARQELAMAQMARYLYDYy ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=A0A3E5IJF1_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] FTU family class A beta-lactamase n=1 Tax=Francisella tularensis TaxID=263 RepID=UPI0003E76FFE ---QLDDSFKNLENKYDGKIGIYTLNTDDKTNI-KYNESYHFPICSVFKFLLVGAILDYDM -HNQGFLDKKIPINQDDIGKYAPITAKNAGKTLTISQLNYAAI-LSDSPASNILVRELGGL -QNLNKFIKKLGDNDTIITADEPEINYTQPHSNINKITPKAITKDIYKLAFGNILDKKHKD -IFIKYLQDNNTGANRIAFGMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIALGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 3783N1-6 TaxID=1339310 RepID=A0A0E2TP44_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMT0_9BACT --qALEGKIAGFLKGKKATVGVAVL-TDKDETI-LHNNEVHYPLLSVFKFHVALAVLDKMN -REEIPLKHIVHVKASQLQPYSPLRQKHSGQDISLGELLQYSISLSDNNACDILIEYAGGI -GHIHQYIKKLGINDFNLSETEDSMHRNPQKAYSNWSTPSEMVRLLKMADEKDLFAPVYRD -FFWKTMTETATGSNKLKGLLPSNTVVGHKTGSSDRNADNDAGVLIMPGGKKYYIAVFVTD -SSETDEENAAIIAHISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Granulicella sp. S156 TaxID=1747224 RepID=UPI00131CB206 ---TLHQQISSIAQDAQGKVFVACSLPGVALDC-DLNAHGHPPMQSTFKLPLAIVVLQQVE -RGKLALDQPIRFLPSDRYPYSPLQDAHPDANVPLSELLQLAVGKSDNTAADILLRILGGP -EVVQDSLNKLGLRTIHVRDSERGLHDDFQAQYRNDAEPAAMVALLRLLADHSPLNAEHTA -LLNRWMTESTTGLHRIKGLLPADTLVAHKTGTSGERANNDVGLITLPNGHRLALAVFVID -SRADETTREAVIARIAKVIYDQ- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMV6_9BACT --sELENRIDSLLNSKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. PhB55 TaxID=2485106 RepID=UPI001066187A ----FGKQLASVANASQGRIGVAAVDLSTGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP -SAVNAWVRRTGIDEWHIDRDIATLVRAKVVDKRDSATPIAVVELLSGIYQGKWMSKQGRD -VLLGAMSRTVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG -QG-TRPNREARIASIARAIYEGy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PhB57 TaxID=2485107 RepID=A0A4R3TC95_9SPHN ----FGKQLASVANASQGRIGVAAVDLSTGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP -SAVNAWVRRTGIDEWHIDRDIATLVRAKVVDKRDSATPIAVVELLSGIYQGKWMSKQGRD -VLLGAMSRTVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG -QG-TRPNREARIASIARAIYEGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unknown TaxID=N/A RepID=UPI00143CA456 --nQLGAALEALLNTKKALIGVAIDGPKDGDSI-RINADMHYPMQSIFKLHIALTILAEVD -KGNLSLNQTVLIKKNELLPWSPIREDYPEGALSLAKVLEYTVALSDNAGCDALLRLLGGP -EKIENHFHNLGFTDFEVKINEEEMQNNWDKQFLNWTTPTESNRVLNAFFTQKLLSNDSHT -FFWDVLKNTKTGKKRLRGLLPKETIVAHKTGYSGSAAVNNVGIVYLPNGDTFTISVFITN -STEDTATNERLIAEICKAAWDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=UPI00138F14D5 --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGYNDIGFVLLPDGRTYSIAVFVKD -SKENSQVNSKTIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A1W6AL02_ECOLX ------------------------------------------------KVMAAAAVLKXSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGXKTGSGGYG------------------------ ------------------------ ->[subseq from] Beta-lactamase n=10 Tax=Bacteria TaxID=2 RepID=A0A127SAJ7_9BACT --sELENQIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=2 Tax=Altererythrobacter ishigakiensis TaxID=476157 RepID=A0A562US25_9SPHN ---SFERRIAQLADGSRGRIGVAAVDLTTGEEI-SVLGDQLFPMASTSKIAVAAAYLEQVE -QGKYSLTSEFPLLIPLRSASSPAAPVREGNYMAADQLIEIMIARSSNPATDALLRAVGGP -EAVNNWVRRQGIEEFSIDRDIATLVRSMHIDRRDAATPRAMIQLLQGLYQGKFLSDESRQ -VILDAMAKTRTGKRRIPAEMPDYVEVMHKTGSLNN-TSSDIGILEGPNGHAIAVAIYVTG -QGA-RRAREARIASIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A3E4XI36_BACUN --sELENRIDSLLNGKKTTVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. 32-60-15 TaxID=1970410 RepID=A0A258I0E6_9SPHN ---YIQQQIAAIAAEGRGRIGVAAMDLDGGGQV-FVNGDMPFPMASTAKIAVAATFLEQVE -KGTYRLDQQFPMMLRVRETLGPVAPLREGTVMTAQSLMELMITRSHNEATDGLINVVGGY -ENVNRWLTRNGITGQRLDHTMATLVRARVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVAFFVTG -PEG-HAAHAKLIARMMRTIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus chromogenes TaxID=46126 RepID=UPI000D1CCC02 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLR-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Listeria cornellensis FSL F6-0969 TaxID=1265820 RepID=W7C8Y6_9LIST ----------------------------GKQTI-NFNAEERFAYASTFKAIAGGILLKNLT ---DEQLNKRFTFSKEDLVDHSPITEKHVASGMTMKELINASMTYSDNTAANLTLQQLGGP -KGFEKELLKIGDKTMKPVRYEPELNDAVPGDIRDTTTPEAMAKTLAYLLTNGNLPADRLA -YFKQTLIANTTGGTLIRAGVPNGYVVGDRTGAGSYGTRNAIAMIYPKNKKPLVWVIFSKK ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Fischerella muscicola CCMEE 5323 TaxID=2019572 RepID=A0A2N6JZ96_FISMU ---SLKTNLQSLTSANNLTPGVFVVDLENGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMIVGGSGDMQYKPAGTFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTAIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVQR -PNND-PRAEKLIGSISRAAYQQf ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Methanosarcina mazei TaxID=2209 RepID=A0A0F8JIU6_METMZ --------------------GYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTL---- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured Sphingopyxis sp. TaxID=310581 RepID=A0A1Y5PVT2_9SPHN ----LDDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD -QGRMTLDQRVHIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -EAVRAFISKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE -YLLDVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TNASVPARMALMQAVSGAVADY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A415HQU1_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Aestuariisphingobium litorale TaxID=2339262 RepID=A0A419MUM9_9SPHN ----MVAALRAIWSAFPGKAGIAVMKTDGSWMV-SYRGDEPMPQQSVSKLWVAIAVMDAVD -KGQLSLDDQVTLKKSDITLHQPIAGLIGPNGTTIASLLKRAMTQSDNTANDFLMRRVGGP -TAIRELIASKRLGAIRFGPGERHFQARYVADPMDGATPAAIARSLARLKRGELLSAQSTR -YLLNVMESTETGRARLKAGLPAGWKLAHKTGTGQTAGFNDVGIMIAPDGTSYAVAVMIAD -TTAPVPTRQKLIQQVAITVAA-- ->[subseq from] Beta-lactamase n=6 Tax=Bacteroides fragilis TaxID=817 RepID=Q57509_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 2-F-2 #4 TaxID=1339280 RepID=A0A015ZMI1_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Class A beta-lactamase n=1 Tax=Ponticaulis sp. TaxID=2020902 RepID=A0A2E0UAN6_9RHOB -------------------------------------------MCSSFKWLLAALVLKQVD -AGDLLLEQTVYFTREDMVPHAPVTESALGLGLTVAELCEATVQTSDNPAANLLLRLIGGP -EGFTEMLRADGADTTRLDRWEPELNANTPGDPRDTTTPNAMVSLMGYYLFGAGLSGRSAD -LVKEWMTGATTGLDRLRAGFPDYWISGDKTGTSSNDQTNDVAFAFQPSTQPVLISSYLNV -SDP--MTRDPVHAEIGQLVMK-- ->[subseq from] class A beta-lactamase n=1 Tax=Moraxella osloensis TaxID=34062 RepID=UPI00132E8E5A --------LPSWENKLNAKIGMAVITASNNELA-SYRGNDFFPFNSTIKAFIGAYILHLVD -KGQLDLAQTLQIKATDLLEYAPQSKKFFEANISIAELSEAMITVSDNTASNLLLDTTGGL -KPFNDFLHQIGNSEVILVHNEPLLNRSHYGDKIDTAKPIAYTQALKNILMGDILSEQSKK -LLLTWLINDKVGDSLLRKHLPKDWQIGDKTGAGDE-SRNIVAIVWNSQKEAYFVSLFITQ -PYKSNNQKSVAIAEIGQAIYS-- ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus TaxID=1279 RepID=A0A3N0HUB2_9STAP ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KGFQQALIHRGDHITNPQTLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE -LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0G3FAD5_KLEPN ------------------------------------------------------------- -------------------------------TMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAA------- ->[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8HS92_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEQIIHIRPEQLLKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFALIGGT -GTVQKDLKEWGISGINVRFTENEMLRNHDLQYVNSSRPSAMNALLRAFDEGKILNKDTQR -FLWDIMAGCSTGATRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSLPACEKVIASMARWLCTEw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=UPI00125FA781 --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -ETVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. AM54-2NS TaxID=2292955 RepID=A0A3A5R1H7_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALTDYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=Q849S7_KLEOX -------------KRSGGRLGVALINTADNSQI-LYRGDERFAMCSTSKVMAAAAVLKQSE -SNKEVVNKRLDINAADLVVWSPITEKHLQSGMTLAELSAATLQYSDNTAMNLIIGYLGGP -EKVTAFARSIGDATFRLDRTEPTLNTAIPGDERDTSTPLAMAESLRKLTLGNALGEQQRA -QLVTWL------------------------------------------------------ ------------------------ ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium jejuense TaxID=445960 RepID=A0A2X2VRR9_9FLAO ---EFKKVIETIIAHKKADIGVSIVTAGTKKEVtQINGNKPLPMLSTFKFPVALAVLHKVE -KGELSLQQKIYIKKEELLEYSPFREKYPEGNLSLEECIHWMMVYSDNNLTDILIRLIGGP -DYVQNFINS---KDIVIKNDEEGMHKDWDSQFINTITPNAAIRLLEQFYNGKILNKEHTK -WLYTVMINNATGTKRLKGKLPKDVKVAHRTGTSFTGAINNYGIIELSDKKRIYIAVFIHD -TFETFENSEAIIADIAKAAYNYy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A5N0M834_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALTDYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WPN8_9BACT ---DLTALIEKTAAPAKGRVGVFAVVLETGESV-DLDPDGQYPMQSVFKLPISMAVLRQVE -EGKLKLDQKVKVEKADYVRRSPLRDKNPNGAVTVEELIRLSIVESDGSASDVLTRLAGGA -GEIQAYLTGINIGEMIVANTEKEIGQDWETQYRNWASPEGAAALLRALHEKRGISEPHQK -LVLKFMVESVPGAKRLKGMLPAGTQVAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVSD -SPADEATREGVIAGIAKACWDTw ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. FGD1 TaxID=2692619 RepID=UPI00136B4BF6 ------QQLAAVANASQGRIGVAAMDLSTGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWSLSSEFPLMVPVASRSSAVAPVRPGEYMTASRLIELMITRSNNYATDALLKVVGGP -KAVNAWIDRAGIEDWHIDRDIATLVRARVVDKRDSATPLAMVKLLSGIYQGKWLSPSSRS -VIMGAMSRCVTGRRRIPAGLPAEARVSHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG -QG-GRPGREARIASIARTIYNGy ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium acidiphilum TaxID=505248 RepID=UPI00048CBBF7 ---AIQQNIESIVARARGRVGVAAADLDGGGEV-LIHGDMPFPMASTVKIAVAGTFLTGVE -QGRYRLDQSLPMMMPVAERGARSAQAPVRPGMSAQQLMELMITRSDNHATDGLISAVGGV -SAVNAWLARTGIVGQHVDSTIATLVRATTIDTRNASTPRAMLSLLAAIDRGTALSPQSRA -VLLDTMTRTSTGKNRMRAGLPDGTVFAHKTGTLQ-GVTDDVGIIRLPDGRHLALVIFVAG -PEG-HTSHAMLIAQITRALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI00132F7074 ---TLDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSIFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTVSQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSDINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWTIGDRTGTCGYAATNDVTIIWPQNKPPFALSILYTN -PSLKAPSNEKIIQQASKLTVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Francisella noatunensis TaxID=657445 RepID=UPI0013627EBA ---TLDDSFKNLEDKYHGKLGIYTVNTDDKTNI-SYNENYHFPICSIFKFLLVGAVLEYDM -QDKGFLDKKILITQDDIGTYAPVTGKNIGKTLTVSQLNYAAI-LSDNPAANILVREIGGL -EKLNKLVAKLGDKDTIIKNDEPKINHTKPDSDINKTTPKAITQDIYNLAFGNILDKKHRE -IFIGYLQKNNTGANRIAYSMPKNWTIGDRTGTCGYAATNDVTIIWPQNKPPFALSILYTN -PSLKAPSNEKIIQQASKLTVD-- ->[subseq from] Beta-lactamase n=23 Tax=root TaxID=1 RepID=BLAC_BACUN --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium sharifuzzamanii TaxID=2211133 RepID=UPI000DAF137F --nELRNQLHQIISNKSATLGLSMKGIEDKDTL-SINGNLKMPMMSVFKFHIALAVLHKVD -EGKLNLTQEIFIKKKDLKEWSPMKVDYPEGNLTLDKILRYTVSHSDNNGCDILINLVGGT -KYIKKFINEQGIRDFVIKMNEDQMKT-WKNLYVNTTTPIATTELLEKFFKGEILKQETTK -YLYQLMVETSRGLTWMKAGLPENTELAHRTGISGTNAMNDIGIVKLPNGKHFILSVYLKD -ITEKREDTEKIIADLTKAVWDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5NA29_ECOLX ------------------------------------------------------------- -----LLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGNKTGSGGYGTTNDIAVI---------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. PP1Y TaxID=702113 RepID=F6IHB4_9SPHN ---QFEKQLASVAEASKGRIGVAAVDLATGRTI-EVLGDQRFPMASTSKIAIAATFLAGVE -KGKWSLTSEFPLMVPVASASTPIAPVRPGAYLSARDLIEQMITRSNNYATDALLKVVGGP -KAVNDWVHNAGIEEWHLDRDIATLVRAQVIDKRDSATPLAMVKLLNGIYDGKWMKAESRD -VILGAMSRCRTGRRRIPAMMPDGVTVSHKTGSLNN-TSSDVGIIQTPDGHAFAVAIYVTG -QG-SRPNREARIAQIARTVYDGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=UPI0005CBD566 ---SLETQLKEAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG -KRNQSLDTLLTVEKSDLKPYSPLRDKYPEGGMSIAELLKYTLQQSDNNACDILFHYQGGP -DSANKYIRSLGIQDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRREPLFAKEYKD -FIYQTMVECQTGQDRLIALLDKGVIVGHKTGTGDRNGCNDIGFVVLPDGHTYSIAVFVKD -SEESSPENSKIIADVSRIVYEY- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Sphingobacterium paludis TaxID=1476465 RepID=A0A4V3E1M2_9SPHI ---SLENQITSFIQDKKAFVAVAIQEGHHGDIV-QIHAEEKLPMQSVFKFHIAVAMLTEID -KGTFQLDQPITVSKEDLTPWSPLRDDYPQGAIPLSTLLTYMVAQSDNVACDVILKLLGGP -EQVDLFFKEKGVKNLAIKINEKTMQSNWEAQFQNWTTAEECNNLLKTYFYKKELSPESHS -FLWTVMKGTKTGLKRLKGDLPANTVVAHKTGYSGTEAAHDVGIIFLPDNKPLFISVFVSR -SKEELAVNEEIIARIARMTYDFy ->[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 3986 N(B)19 TaxID=1339289 RepID=A0A015VDJ1_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNKNLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPGGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SKB4_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] CGA/CIA family class A beta-lactamase n=1 Tax=Chryseobacterium timonianum TaxID=1805473 RepID=UPI00083B73C9 --sTLEQKINTIIKGKQATVGVSVLGFEDPIRY-SQNGNKKLAMMSVFKFHVACAALDLVD -KGKLSLDQKIFIKKSDLYEWSPYRVKYPEGNATVSEIIDYTVALSDNNLCDILIELVGGT -QAVQKFMDFKGVKDFQIKYSEHGMANGWDSLYKNYTTTNSTVDLLKKFYEGKLLSKGSTD -YLMQIMLDTKTGANKIVEQLPKGTPAAHKTDSSGRKAENDMGIITLPNGKHYAIAIYVSN -SKESEAENCKIISNISKAVWDNf ->[subseq from] class A beta-lactamase n=1 Tax=Mucilaginibacter sp. HC2 TaxID=2714892 RepID=UPI00140A2F6D --qSIRQQVIKIASGIKAQVGVSAMIVETGDTV-NYRAGDKFPMQSVYKLPIAIAVLHQVE -LGRLSLNQQVKVSPTEIIPVSPIRDRYAHGVLSILELLRYNVSDSDGSACDVLIRILGGC -QKINQYIHSVGIRDIAISTTEMVQVSDDWVQYRNWVKPEAMLLLLKKFYAGQLLNRSHNE -LLLNLMIKSGPGAKRLKGMLPAQAVVAHKPGSSGTRTTNDVGIITLPNNKHLLIAVFIAD -TYADTEEREGVIAQIAKAAWDNw ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium pentaromativorans TaxID=205844 RepID=G6EB29_9SPHN ---QFEKQLASVAEASKGRIGVAAVDLATGRTI-EVLGDQRFPMASTSKIAIAATFLAGVE -KGKWSLTSEFPLMVPVASASTPIAPVRPGAYLSARDLIEQMITRSNNYATDALLKVVGGP -KAVNDWVHNAGIEEWHLDRDIATLVRAQVIDKRDSATPLAMVKLLNGIYDGKWMKAESRD -VILGAMSRCRTGRRRIPAMMPDGVTVSHKTGSLNN-TSSDVGIIQTPDGHAFAVAIYVTG -QG-SRPNREARIAQIARTVYDGy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SN23_9BACT --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A522CNG4_9CAUL ----LQKAVDAIAATAPGMLGVGLMNLESGQSF-LTNPDRPFPMQSVFKLPLAAAVLGEVD -AGHLGLTTRLTILEDQLSPHSPIATAWPGRRYTVEELLEAVLIESDNTAADVLMSHIGGP -GVVTAWLIGKRVPEIRVDRYERELPARYMADPRDTSTPRGMLEFLQRLDRGELLSADSTR -RLTDLMSRCTRGAGRIRAGLRPGAFLAHRPGTSGSTVHNDVGVFTLADKRAYALAVFLSG -ATLDDTGRDRVIAQVASAAVR-- ->[subseq from] Putative Beta-lactamase (Precursor) n=1 Tax=Streptomyces viridochromogenes Tue57 TaxID=1160705 RepID=L8P2T9_STRVR ------------------------------------------------------------- ----------VRYSRDDLVADSPVSENFVKTGMSLRGLCAATLWYSDNTAVNLLFDELGGP -DGLEKVLEEFGDDVTEMDRYEPDMSEGAPGDIRDTSTPRAMAGSLRAFLLGDALKADERE -LLRQWMTTNMTGRTLIRAGVPDGWDVADKSGTAGYGGRNNIAVVWPDDGNPIVMAVMSSR -DKQGAERDDALLAKAAAVAVK-- ->[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. Ery12 TaxID=2306996 RepID=A0A419R2R6_9SPHN ---ALERLVGRIADGSQGRIGVAAVDLVTGQQV-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWSLSSEFPLMVPVRSASSAVAPVRPGQYFKAIDLIEMMITRSNNQATDALLKVVGGP -RAVNKWVRAQGIEEFQIDRDIATLVRAKQIDTRDSATPKAMVKLLTGLYQGKYLNEASRR -VILGAMERCRTGSRRIKALLPDSAIVAHKTGSLNN-TSSDIGVIKAPNGHAIALAVYVTG -QG-SRPAREAKIASIARTLYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000C1BBFEF ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKK -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDV------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI0011857F6F ------------------------------------------------------------- -----------------------MTKNHINGGITVSELCAAALTLSDNSAAKLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQRI -QLQTWLKNNTTGNAKIRAGVPKDWIVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFTK -NKKGAVSPDSIIERITRILM--- ->[subseq from] Beta-lactamase n=1 Tax=Francisella adeliensis TaxID=2007306 RepID=A0A2Z4XY48_9GAMM ----LDASFKKLEDKYSGKIGVYSINNTDKSLI-EYNENYHFPICSVFKLLLVGAVLHEDM -QNEGFLDKKILITKKDITNYTPITGKNIGKHLTISQLSFAAI-LSDNAAGNILIEQIGGL -NKLNLFIKNLGDENTIINNNEPKVNNTTPESNINKTTPKSITRDINELIFGNILDDKHKK -IFIKWLQDNNTGKNRIALNAPKNWIIGDKTGTCGYGSTNDVAILWSPNKNSIALGILYTN -PEKNAKNNEKIIQEATKLITN-- ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D7DE8A ---RLERELLRLSDISGGKVGICAVHIESGKTI-LQNSKDRYPMASSYKVAIATQLLSRVD -SGAISLDQLITIEKNDLHPGSGMIS-----TLSVRSLLELMLLISDNSATDICLRLAGGS -AAVNACMNRLGIEGLQVDRPTAWLIAAFENDPRDTSTPEAMTLLLTKLYTKPVLKPDTQT -LLLDIMRRCETGLARLKGALPPDTEVLHKTGTLGL-TASDVGIITLPDNGHVAISVFVKS -SKKDGNSRERAIAEVTRTIYDYf ->[subseq from] CblA family class A beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00125E7B8F --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMRYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CAC6_ECOLX ----------------------------------------------------AAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTT---------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium guangzhouense TaxID=1850347 RepID=A0A2K2FZF1_9SPHN ------QQLAAVANASQGRIGVAAMDLTTGRMV-DVLGDQRFPMASTSKIAIAATFLEGVD -KGKWSLSSEFPLMVPVGSASSAIAPVRPGEYMPASRLLELMITRSNNYATDALLKVIGGP -KAVNAWIERAGIDDWHIDRDIATLVRARVVDKRDSATPKAMVNLLSGIYQGKWLSPSSRN -VLLGAMSRCLTGKRRIPAGLPTDVKVSHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG -QG-GRPGRETRIASIARTIYNGy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium barchaimii TaxID=1420591 RepID=A0A561HXT9_9SPHN ----FGKQLASVANASQGRIGVAAMDLSSGRMV-DVLGSQRFPMASTSKIAIAATFLEGVD -KGKWTLSSEFPLMVPVPSASSTVAPVRPGTYMSARQLIELMITRSNNYATDALLKVVGGP -SAVNAWVRRTGIEDWHIDRDIATLVRAKVVDKRDSATPIAVVELLAGIYNGKWMSKQGRD -VLLGAMSRTVTGKRRIRAGLPAEVTVSHKTGSLNN-TSSDIGIIETPDGRAYAVAIYVTG -QG-TRPNREARIASIARTIYNGy ->[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. NIES-4103 TaxID=2005458 RepID=A0A1Z4S812_9NOSO -----KDAVQNLVAANNLSPGVFLVDLDTGSYV-DVNSTASFPAASTIKVPILVAFFQEVD -AGKIRLDEMLTMQQDMVAGGSGQMQKPVGTQYNALEVATKMITISDNTATNMLIARLGGM -DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPRELANLMAMLNQGNFVSMRSRD -LMLDIMRRTAR-DNLLPSGLGAGARIYHKTGDIGT-MLADTGIIDTPTGKRYIAAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Prevotella oryzae TaxID=185293 RepID=UPI0004B91663 -----RKGINKIIKGKHATIGVAIYDTQTGNTL-NINGDKHFPMQSVFKFPIALNILTKVD -KGKMSLNDSIFITAKDLLPWSPIRDRYPEGNMPLSEIIRYTISQSDNNGCDILIHLLGGT -STVNSYISSLGLTEMKIKKTEAEQHITPSAQFYNWTTPTCAIQLLRLFHEKKILLSDSRD -FLFKTMTETSTG--SVKTEIPQDVIVAHKTGSAFY-VVNDIGVMQIPDNHTILYAIFIMK -SKESKENNYKIIADIAKVVYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=A0A413N2X4_BACUN --sELENRIDSLLNGKKATVGIAVW-TYKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A5N4EU35_BACOV --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Class A beta-lactamase n=1 Tax=marine bacterium AO1-C TaxID=1905359 RepID=A0A1Q3GHK8_9BACT --qALKEKINQVLKGKSATVGVAIQGVNATDTL-SINGNKHLPMQSVYKYHLAMAVLHQVD -QGKFRLDEKISISKKTVKAWSPLRKKYPNGAVALSEIIKYTVAWSDNVGCDLLFKLIGGP -KVAEAYMHKIGIQDIAIVDPEIKMQAKWKRQYKNWTTAKAANQVLQLFFKNNLLSPKSYN -FLLNVLKGTKTGKKSIRGLLPKDAVVAHKTGHSGTGALNNIGIVFLPGNSYFYISVLVSN -SMESSATNQKIIAEIAKLTWDYf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. Rr 2-17 TaxID=555793 RepID=I9WD20_9SPHN ----FEQQLAAVAEASKGRIGVAAMDLTSGRMV-EVLGHQRFPMASTSKVAIAATFLDGVD -KGRWSLSSQFALQVPITSAFSTAVAPVRGGDMSAQQLLELMITRSNNYATDALLKAVGGP -SAVNAWIARAGVADWHIDRDIATLVRARVVDKRDSATPIAMVQLLSGIYQGKWLSPSSRN -VLLGAMSRCVTGKNRLRAGLPTDVLVSHKTGSLSN-TSSDIGLIQTSDGRVFAVAVYVTG -QG-SRPNREARIASIARTVYNGy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caecimuri TaxID=2516958 RepID=A0A4S2CY52_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRMVALLDKKVTVGHKTGTGDHNGCNDIGFVLLPDGRTYSIAVFVKD -SEESFADNSKIIADISRIIYEY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium MED-G03 TaxID=1986231 RepID=A0A2A5YFA4_9SPHN ---KLLAEFERFAALSDGTVGIAVRDLQTGETQ-SFNGDTLFPMASAYKVAVAGRIFALVD -AGELRLDDQLALDPALASEGIAWMFSRPGAALSVQRLLELMLQKSDNNATDVLVARAGGP -QAITRFVTGLGVNGLRVDSDTAHLLYSFATEIEDTSTPRAMLDLLSAYESGRALSADSTQ -RLFTIMAHCETGKHRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK -DGKGHKARDRIIAEAARAAYDYf ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. NIES-4103 TaxID=2005458 RepID=UPI000BBC8B61 -----KDAVQNLVAANNLSPGVFLVDLDTGSYV-DVNSTASFPAASTIKVPILVAFFQEVD -AGKIRLDEMLTMQQDMVAGGSGQMQKPVGTQYNALEVATKMITISDNTATNMLIARLGGM -DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPRELANLMAMLNQGNFVSMRSRD -LMLDIMRRTAR-DNLLPSGLGAGARIYHKTGDIGT-MLADTGIIDTPTGKRYIAAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bacteroides fragilis TaxID=817 RepID=A0A2M9V5D9_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacC n=1 Tax=Fuerstia marisgermanicae TaxID=1891926 RepID=A0A1P8WHV6_9PLAN --eTLAAKIQPLIDRHDGDVGVYVQHLTSGVKF-QHRPDAVMPTASLIKLPVMIEAYRQAD -AGTIDLDSMLTLHDSDKVPGSGILTTHFSDGLSLRDAIRLMIAYSDNTATNLVVDAI-GM -KATAETMEKMGFPETKLHSKVYRGSSRSQQYGLGSTTAADIVALLQQLHEGKLVSPKACD -DMKAHLLACED-KKKLPRFLPAGVKVAHKTGSVSK-SRCAAGLMYTRSG-PIAICVLTSN -NKGDKNAGDLLCSHIAKAACDYf ->[subseq from] Beta-lactamase n=2 Tax=Rhodanobacter sp. OK091 TaxID=1881037 RepID=A0A1M7BRP4_9GAMM ---RLQQTLDALARRAPGTLGVAVLDLQSGAEA-SVNGGQAFPMMSVFKAPVAAAVLWRID -EGKLSLQQQVTLTRADVLSGSPSIGAHFRGEFTVEQLLKAAVSESDNTAVDALVKVVGGP -QVVTAFLRVHGIDGMRVDLDEAGVGRAFLAAPYNRSTPDAAVMFLRKLHGNELLTPASTQ -HLLDLMAAQTI-PNRLRAGVPRGVGLADKTGTSYMASFNDIGILSGPNGHTVIVAAFLTD -SSASEAERNALFADIARAAATSf ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012965DA1 --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLEGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRVGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAAARAITAAy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD52_ECOLX --------------------------------------------------MLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWYFA--------------------------------- ------------------------ ->[subseq from] Truncated beta-lactamase n=15 Tax=Gammaproteobacteria TaxID=1236 RepID=B9VVU8_ECOLX ------------------------------------------------------------- --------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Kluyvera georgiana TaxID=73098 RepID=A0A3S7Q8H5_9ENTR ------------------------------------------------------------- --------QRVEIKLSDLTNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLITHLGGP -GEVTAFARAIGDRTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGNALGETQRA -QLVTWLKGNTTGAASIQAGLPKSWVVGDKTGSGDYGTTNDIAVIWPQGR----------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Myroides guanonis TaxID=1150112 RepID=A0A1I3QLD4_9FLAO --eKLRDSIEAILRNKNAVVGVAINGMNESDSL-SIHGSRHFPMQSVFKFPIALTMLSEID -KGNFSLGQKVAIHKNELLPWSPIRDKHPEGALTIAEILRYTVMMSDNVGCDVLLRLLEKP -EVVENYIHKKGFNDFAVKINEEVMQNNWDLQFLNWTTPTEANNILRVFYEGNQLSKRSYD -FIWNVMKETETGKDRLKGQLPKGTIVAHKTGWSGSAAVNDIGVVFLPNGNHFYISVFVAD -SKEDTATNEKIIADITRLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium BRH_c3 TaxID=1734408 RepID=A0A117S7Q7_9SPHN ---SFERRIAQLADGSKGRIGVAALDLTTGEEI-GVLDNQLFPMASTSKIAVAATFLEMVE -QGKYSLTSEFPLMMPLRSASSPVAPVRAGEYMPAHQLIEIMISRSSNPATDALLAVVGGP -AKVNDWVRRQGIKDFSINRDIATLVRASHIDKRDAATPRAMLELLKGLYQGKFLSAESRA -VLLDAMSKTRTGKRRIPALMPMGVTVSHKTGSLNN-TSSDIGIIEGPDGRAIAVAIYVTG -QG-SRLAREERIAAIARELYDGf ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. DSM 18164 TaxID=1881058 RepID=A0A1I1SX72_9BRAD ---KLDAGIKTIEQSTKGRLGVGLTDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAIE -AGKLKLDQPITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLIGGP -QALTAILRDGGVTGISVDRYERVFQPATLTDKRDAASPESSIAFLEGLAKGTWLRDPANA -ALLDIMLEAKTGPNRIKAGLPAGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -AQVGEKEREAAHAAVARLAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Alistipes timonensis JC136 TaxID=1033731 RepID=A0A1H4AJ81_9BACT ---SLGRAVRAVADSVRATVGVAVV-FEEGDTL-VVNNACRYPTMSVYKFHQALAVLNRLD -RSGLPLTTRIPVLRSDLLPWSPLREACPGGGFTVAELLAYSVAQSDNNVCDLLFRFLGGP -EVVNRYIAGLGVGETEIAADEETMHRRTDNQYLNWATPLAAVRLLELFRRGKLLSAESGD -FLLKTMFATETGPDKLRGLLPPGVAVAHKTGSAFRDADNDIGIVRLPDGRSYSIAVFVMD -SREDDRTNAAVIARISRLVYDY- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter indicus TaxID=374177 RepID=UPI00136E5AB9 --sALESRIAQIANGDQGRIGVAAIDLSTGREL-SVLGDQRFPMASTSKIAIAATYLDGVD -KGKLSLSSEYPLMVPVSSKSSKIAPVKKGQYLSARELITLMLTRSSNSATDAILAALGGP -SVVDEWVHRTKITNFTLTRDIATLVRVSHIDTRDSASPKAMVRLLKGLYQGDWLSEQSRS -FLISTMEKCRTGTRRIRAQMPSTVTVAHKTGSLHN-TSSDIGIVTTPDGRSFAVAIYVTG -QG-TRANREAKIATIARAIYDGy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A3E4NAI7_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Beta-lactamase class A VEB n=1 Tax=Pedobacter sp. CF523 TaxID=2135715 RepID=A0A3L9ZQ67_9SPHI ---TLKAQIQEVIKGKRATVGISIIANSFKDTI-NINADVHLPMQSVYKFPISLALLKEIE -KGKFLLQQKIVVTKKDLLSWSPIREKYPTGRMSIAEIMEYAVSQSDNNGCDILLRLIGGT -AQVENFLKQNQLNNISVKTTEEQAQKDWSLQFKNWSTAAALTHLLTRSYENKLLSNANYK -FIWKVMEQTTTGSKRIKGQLPVNTVVGHKTGTSGTAATNDIGVIKLPDGGLIFISVLVSG -SLESEQINEKIISDISRLAYEHy ->[subseq from] class A beta-lactamase n=1 Tax=Legionella rowbothamii TaxID=96229 RepID=UPI001055274E ---ALAKKIREIEKKSHIVMGITAIHIEKNRMI-THNSNQRFFMASTIKLPIAVAFLHLVD -EKKESLSRIIKLSSKNSVPGSGYLHHMFEKKISLQQILKYTLINSDNSASDSLLKAAKGP -EAVKKRMAALGFKDIHVNRSILEMFVRFQNDPRDTTTPNDMAKLLVKVYKNQALSETSTQ -LLMKIMEQCRTGRSRIKGLLPPGVKVAHKTGTWSSGFVSDVGIITLPNKGHIAIAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A520X2Y6_9SPHN ----FAQRIARLADGSDGRIGVAAIDLVSGEEI-SILGDQRFPMASTSKIAIAATFLEGVE -RGRWSLTSEFPLMVPVQSAFSSAAAPVRKGSMPAIDLIEIMITRSSNPATDALLRVVGGP -AAVNEWARRNGIREFSIDRDIATLVRAKHIDLRDSATPRAMVDLLSGLYQGRFLSAESRQ -VLLGAMSRTRTGTRRIPAMIPSSAQVLHKTGSLNN-TSSDVGIIKMPNGRAFAVAIYVTG -QG-TRGQREAKIASIARALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas vulcanisoli TaxID=1658060 RepID=UPI0014243713 ---TLQPRLAALAHSAPARVGIAAIDLTNGEMV-SVNGADRFPMASTVKVAIAAAFLHQVQ -LGRQSLDRVYSMAADERRKASRIGNMRGGRTASGADLIDLMLTRSDNSAADILLGAVGGT -VAVGEWLHQAGVTGQRVDRSIADLLSAPVGDVRDSSTPEAMATLLAKLRSGDLLDSQHTA -YLFDVMARCRTGAHRLKAMLPGDALIAHKTGTLD-GVSNDVGIISLPNGHELAVAVFEQG -SGG-HGPRDRNIAQLGRMLYDGf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Erythrobacter sp. THAF29 TaxID=2587851 RepID=A0A5P9GNS8_9SPHN ----FERRIAELADGDRGRIGVAAMDLKTGEMI-TVLGDQLFPMASTSKIAVAATYLEMVD -QGKYSLTSEFPLLIPVRSAYSSRAAPVRKGKMPAIDLIEIMITRSSNPATDALLDAVGGP -EKVNQWMRRQGINDFSIDRDIATLVRATWIDPRDAATPRAMVRLLQGLYRGDFLSDQSRR -VLLGAMSRTVTGKRRIPAYMPEVARVSHKTGSLNN-TSSDIGIIEYPDGRAIAVAIYVTG -QG-TRRNREARIASIARALYDGf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0H3WME5_ECOLX -------------------------------------------------VLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWLLA--------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium pentaromativorans TaxID=205844 RepID=A0A2W5NKT4_9SPHN ----FGRQLATVAEASRGRIGVAAMDLATGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP -SAVNAWVRRTGIDEWHIDRDIATLVRAKVVDKRDSATPIAVVELLAGIYNGKWMSKQGRD -VLLGAMSRTVTGKRRIRAGLPAEVVVSHKTGSLNN-TSSDIGIIETPDGHAYAVAIYVTG -QG-TRPNREARIASIARTIYDGy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes senegalensis TaxID=1288121 RepID=UPI0002ECF424 --eSLERALRAVTDSVRATVGVAVV-FGDGDTL-AVNGGRCYPMLSVCKFHQALAVLDCLD -RRGLPLTTRIPVRRSDLLSWSPLREACPGGGFTVAELLTYSVAQSDNNVCDVLFRFLGGT -EAVDRYIAGLGIGETVIVADEEMMHRHTDNQYLNRTTPLAAVRLLERFRRGELLSAAYGD -FLLETMFATETGPDKLRGLLPADVAVAHKTGSSDRDADNDIGIVRLPDGRSYSIAVFVMD -SREDDRTNAAVIARISRLVYDY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. AM37-9 TaxID=2292951 RepID=A0A3A5TCC0_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSELKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFCKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEENSQANSKTIADISRIVYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP50 TaxID=1884369 RepID=A0A1H7CEL3_9SPHN --aKLQAEFARFAALSDGTVGIAVRDLQTGETQ-AFNGDTLFPMASAYKVAVAGRIFSLID -AGDLRLDDKLALDPALASEGIAWMFSRPGASLSVDRLLELMLQKSDNNATDVLVARAGGP -QAITAFVTKLGVTGLRVDSDTAHLLYAFSIEPEDTSTPTAMLDLMTAYEEGRAFSAASTQ -RFFTIMAHCETGKARIKGMLPPGTAVAHKTGSLN-GVGNDVGIVRLPDGRRIAMVVFVMK -DSKGHVSRDRIIAEASRAAYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Leeuwenhoekiella sp. MAR_2009_132 TaxID=1392489 RepID=UPI00048C3814 --eNLRNELKAVIINKSATVGVAIHGMREADTL-SINGEKHLPMQSVFKFHLALAILNEVD -NGTLALNTPIEIRKELIENWSPLREKYPNGALELQEILKYTVAWSDNMGCDVLFDLLGGP -AVLQHYLQQLGIDDIAVIHTEMTMQSQFENQFENWTTARASTQLLKRFYEENLLSTESYL -FLLETLKETTTGKSSIKGLLPATTAVAHKTGSSGTAALNDIGIVFLPDNTYFYLSVFVSN -SSEDPETNQQIIAEIAKCTYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LRJ0_9BACT ----LRAEIAKLLPRARGGVGVAIKHFESGTEI-VVNGDEKYPMASAYKLPILVELFYQRA -AGKLNLDDRIEVAPADLHVGSGSMSQLFDAPLSIRNLINLTMRISDNSAADILLNKV-GA -DNVTARMKSLGLTTIRVDRTTQEMIFEFSKAEKDVASPRDMNLLLEKILRGEIVDRATSD -EIIEILKDCQTGLSRIRGLLPQDAVVAHKTGTIG-GSTNDTGIVYLPRGEHLLITVFTKD -AKATAAERDRGIAEISRYAYDYf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00077968BE ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSXKN-------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sp. Leaf33 TaxID=1736215 RepID=A0A0Q4KEQ5_9SPHN ----LTERVAQIAKTDAGKVGAYAIDIDTGAML-AINADNRFPMASAVKLAIAATYLDGVD -KGRWNLATMHMLDEGMRVRSDGITDTLPHAGLSGANLIELSLTVSDNTATDMLLKAVGGP -AAVTRWLQSKGIDGQRVDRTIARLLIAFDADPRDSTTPRAMGELIARLRKGELLKPATTT -FLFDVLARCKTGTKRVKALLPMGTRWAHKTGTLP-GISNDVGVLTLPNGHRVAIALLSYG -IA-DPTTRDARLAEIGRTVFDAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SX63_9BACT --sELENRIDSLLNGQKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E1FF925 ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAERNQQI------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Fischerella TaxID=1190 RepID=A0A1U7GW35_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILIAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] Penicillin-binding protein n=1 Tax=Fischerella sp. NIES-3754 TaxID=1752063 RepID=A0A0S3TIV7_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILIAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIASISKATYQQf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. 16-62-11 TaxID=1970405 RepID=A0A258XFD4_9SPHN ----IQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE -KGNYRLDQQFPMMLRVAEKGTPSPEARPGSVMTAQSLMELMITRSHNQATDGLIKVVGGF -DNVNRWLTRNGITGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGVPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVTFFVTG -PEG-HAAHAKLIARMMRTIYDGy ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q57150_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. J-143-4 TaxID=1339271 RepID=A0A015WLG6_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD -SEADNRENSKIIAEISRIVYEY- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WLS8_9BACT ---SLAPSLLALQKESGGILGVSIQNMETGDTI-SLNGEKPLVMQSSFKFPIALAVFNEIE -NNRLSLEKKVKITKSKLPKWSPLRDQLKENTVSVRELLVFMVSHSDNIACDYLLDIIGGP -STVQNFIHQKGIKNIAIKYSEAEMGKTWEAQYQNWVHPKAMSDLFIKLFHEELLSPEHTK -HLIKLMEETTTGAGRLKGLLPENTIVAHRTGTSGRNAVVDAGVLFLPNGQHAAISVFVTG -SGKETPEIEAVIAKIGRAVWDLy ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI000E1D23CB ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TINNDIHYPMMSVFKFHQALALADCMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase family protein n=1 Tax=Bacteroides fragilis str. 3976T8 TaxID=1339314 RepID=A0A016BZA7_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A3E4Q5I8_BACUN --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQNISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISLSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase class A n=1 Tax=Syntrophus aciditrophicus (strain SB) TaxID=56780 RepID=Q2LTC4_SYNAS --qRLKSEIHRIAVLTGGTVGLSALHIESGRCF-SLNGMERFPMASAYKIPIAVQLLSRVD -CGDVDLDQFVTIRGSDIHPGSGLTFKKKAASYTVRELLELMLLVSDNTASDALLNLAGGP -EAVTAFMKTLGIRDLDVSRSTLNMLARFYSDIRDTATPDAMTRLVAMVHCGTVLKPESTT -LLLKIMERCKTGQSRIRGLIPPGMATANKTGTIGPGIVNDVALLTLPGDGHLALTIFIKS -SDRSLSYQEQTMAQIARYLYDYy ->[subseq from] Beta-lactamase n=2 Tax=Woeseia oceani TaxID=1548547 RepID=A0A193LK73_9GAMM --eRLEAEIARIAAGTKGEVGVAMRRIGSDTTI-GYNLRQRFPMASTFKIAVAGATLAMAE -RNEITLQEMVMVDPLLVVPIDKMARHHPGVMLSVLNLINLALTVSDNTATDVLLSKIGGV -DTVNDWLKSIGIKGQRVDSNVAHLLYRFAADPRDSSTPLAMVDLLEKIQTGAALGAEATH -ILLDIMDKATSGKNRLAGRLPENTPVAHKTGTLA-GMANDAGLVELPDGSKFAIAVFIKL -DEGSLAARERIIANISRAAYDYy ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H115 TaxID=1759073 RepID=A0A0W1CI55_9SPHN ----LNDRLYSLWRAFPGKTGIAVQRIDGEWTL-SQRGDELFPQQSVSKLWVALAVLDAVD -QGRLRMDQPVRIGPEDLTLHQPIAARVRSEGMTVRELIETAITHSDNTANDSLLRTVGGP -GAVRAFISKMDLGAIRFGPGERLLQSNYLANPVDGASPAAIASALTRLARGTLLSPESTD -YLLGVMSRTRSGPKRLKAGLPAGWKFVHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGT -TTSSIPSRMALMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Gramella sp. KN1008 TaxID=2529298 RepID=A0A4Q9V3F2_9FLAO --hELKNKFSTIADSSSGNIGVSALHIENGDWV-SLNGDTHFPMQSVYKFPIAMVMLKKID -QGDFSLNDTIFIDKSEYIPHSPIRNMYPDGVLTIEQILEYNVSQSDGTACDVLLRLLGGT -EEVEKYIHELGVTNIAIATTEMIQVANDTIQYQNWATPEAMNKLLVILHKAEYLSKDSHS -LLEKYMSSNNWFDRRIKGLLPEGTEVIHKTGTAGTRATNDVGIIKLPDGNHIAISVFVSD -SYDSQKKREMIIAQVSKAAYDYw ->[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. TM07-1AC TaxID=2292363 RepID=A0A3R6RER7_9BACT --eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TINNEDRYPMMSVFKFHQALAVLNYLQ -QNNLPLDTPIRIEKEDIIEYSPLRDKYPQGNLPINELLKYIIQLSDNIACDVLFKYIGGP -SVADKYIRSLGIQQFSIVITEDDMHQDLSACYLNWSTPLEAARLLEILLTRSLFKDEYQE -FLKNIMIECETGKDRLPQLLKTDAVIGHKTGTSDKGGTNDIGFVLLPNGSRYTVAVFIKD -SNESMETNAKIISSISEVIYKYf ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=2 Tax=Empedobacter brevis TaxID=247 RepID=A0A511NHZ9_9FLAO --eRLRTEINQIISSKNLTAGISLKNIENKDSL-SINGNQMMPMMSIFKFHIALTVLHEVD -QNKLQLDQKFFIKKRDLLPWSPILDDFPEGNLTLDQLLRYTVSHSDNNGCDILLKIIGGT -KIVQNFIHKQEVKDFVIKVNEQEMQN-WDNLYINTTSANATAKLLEKFYTNKVLKKNSTT -YLYQLMVETSRGSTWMKAGLPANTELAHRTGISDTNAMNDIGIIKLVDGKRIILSIYLKN -ITEERAETEKVMADITKAVWNYy ->[subseq from] Beta-lactamase CARB-3 (Carbenicillinase 3) n=1 Tax=Photobacterium damselae subsp. damselae CIP 102761 TaxID=675817 RepID=D0Z431_PHODD ---------------------------------------------------------ADSD -KDKSVLTYPVVIKKSELVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRSVGDSTTRLDRTEPTLNEAKLNDPRDTTTPIAIAETLNKLMLSEILTKPSQQ -QLITWMEGNQVAAPLLRSVLPKGWKIADRSGAGGFGSRGITAVVWPTEHEPMVVSIYIQQ -SSASMDERNKAIATIGKQVFTYf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. 17-62-19 TaxID=1970406 RepID=A0A259DTC8_9SPHN ----IQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNGDMPFPMASTAKIAVAATFLEQVE -KGNYRLDQQFPMMLRVAEKGTPSPEARPGSVMTAQSLMELMITRSHNQATDGLIKVVGGF -DNVNRWLTRNGITGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGVPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVTFFVTG -PEG-HAAHAKLIARMMRTIYDGy ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_02_FULL_61_11 TaxID=1797950 RepID=A0A1F9VTH8_9BACT ---AMVESLDKLSRSYRGRVGIYIRDLETGKTW-AYNAEKLFPSASLIKVPIMAAVFEKIK -LGEFTLDTQIKLTRPSRVGGSGSLKWVREGTLSVMEIVYKMITESDNTATKMLIDQV-GM -PYLSEAFKKLGLEHTNITPEGMSLSS-YRVKRENYTTPREMASLLERIYAGELVNRESSE -FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE -AP-NYTTAKNFISKVAKLTYRYy ->[subseq from] Beta-lactamase n=1 Tax=Dyella japonica A8 TaxID=1217721 RepID=A0A075K399_9GAMM --dALQHSLDALAQRAPATLGIAVVDLSTGASA-RVNAEYAFPMMSVFKAPVAAVVLSRVD -EGTLSLQEPVEITRGQVQGGSPSIGAHFRGEFTVEQLLKAAVSESDNTAVNALIRTVGGP -AVVTGYLHAHGIDGMRVDLDEAGISRAFLDDPRNRTTPDAAVAFLHKLVDRELLSPASTQ -RLLALMEAQTI-PNRLRAGVPSGLRFADKTGTSGTAAYNDIGIITWPDGRRVLVAAFLLD -SSMTDKERGQLFADIARQVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Bosea sp. BK604 TaxID=2512180 RepID=A0A4R3EDT8_9BRAD ---KLDAEIPVIEQQTGGKLGVALIDLKDRKSW-SHRGKEPFPLQSVFKLPLGIAVLQAVE -AGKFKLDQPITVTRKDLSLHSPLAKSFKGESYPLRDLLTRATGDSDNTAADLLLRLVGGP -QVVTKMLRDGGVEGISVDRYERVLQPSVLDDKRDSATPEASIAFLDGLAAGNWLREPAHA -LIEKITVESKSGPQRVRAGLPEGARFAHKTGLGPNHATNDIGIVTLPNGRRFAIAVYLKG -ATVDEKAREAAHAAVAKAAVA-- ->[subseq from] serine hydrolase n=1 Tax=Tolypothrix sp. PCC 7910 TaxID=2099387 RepID=UPI0014278DEF ---SLKTAVQNLAAANNLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-PRAEKLISGISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A6A0IJK0_9BACT ----LADAVAAEARRCGGHVGVHALHLPSGRSF-SLEAGTPFPMASVYKLPIALAVLGAVD -AGQLTLDEALPVEEGDFRRGVPARERFRAGVLRVEEALRLMVRESDNTATDLLLRRIGGP -AAVQARLGELGLAGVRVDRTEIRMAAAFLTDPRDTATPAGMTALLARLVAGDLLSGPSTS -RLLGWMRDSPTGARRIRAGAPAGSVVQDKTGTHWS-GANDVGVVDLPEGGRLLLAVFVKG -SDLPVPEQEDAIAGIARLLA--- ->[subseq from] Beta-lactamase n=2 Tax=Dyella sp. DHOA06 TaxID=1920169 RepID=A0A3S0RGC4_9GAMM ---TLQAQIDALAKRAPGAFGIAVLDLQSGDTW-QVNADKAYPMMSVFKAPVAATVLSRIE -HGQNTMDQTVTVTRADL-GYGPIRDQFKGEQFTVRQLLAAAVSKSDNSAVNALVRLVGGP -TIVTAYLREHGITGMRVDRDEAGIGRRFMADPGNRSTPVAAAAFLQKLWHNELLSPASSK -YLLDLMYAQTL-THRLRGGLPPGVKLADKSGTSDSAAYNDIGIMVWPDGHAVIVAAFMSG -SNAPPKQRDAMYAELARDVAK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. ZX TaxID=2606412 RepID=A0A5D9C6Y1_9SPHN --qRLDARLEAFTQRKDIRVGIAAVHLESGAAL-SVNGDEAFPMASAYKLAAVLTLLHQVE -QGRFTMDQMIPVDDALRVQSGGISTSMPHPGLSVANLIDLTITRSDNTAADMVTQMVGGP -AAITAWLRSVGIEGQRVDRDVAGLIFAFIADPRDSSTPDAMVALLAKLQRGQLVDAEHTA -WLLDVMAHTVTGAKRVKGLLPPRTVFAHKTGTLV-GICADVGILTLPGGGHVAVAIFVKS -HD-DGAKAEAIIAEAGRTIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 TaxID=1801944 RepID=A0A1G2WBK6_9CAUL --------------ARPAALGVGLSNLESGQAY-TFNGDRRFPMQSVFKLPLAAAVLAEAD -AGRMMLAEPFVLTEEQLSPVSPIAAAWPGRRYTAQALFEAMVIDSDNTAADVLMKRIGGP -GAVTAWLTARRVPEVRVDRYERELQPRYMSDPRDTATPRGMLEFLQMLDRQELVSPASTK -RLIELMGRTRRGGERIRAGLPRDAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG -STLDEGGRDRIIAEVTRAAVR-- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5205 TaxID=2019671 RepID=A0A2N6MLV8_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDETLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVQR -PNND-PRAEKLIGSISKATYQQf ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. M8 TaxID=1925550 RepID=A0A1Q8IIN4_9NOCA ------------------------------------------------------------- ----------------------------------------------DNTAGNLLLRRLGGP -TAVTAFARSLGDTVTTLDRWEPELNSAEPGDVRDTSTASGLARGYRELLLGSGLPAAGQQ -TLTGWMRASVTSGQRIRAGLPAGWTAADKSGAGRYGTVNDAGVLWSPDGSPLVLVLLSDS -VTPDAAHDNAAIAEATAVIVE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=UPI00125FF6A9 --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIANISRIVYEY- ->[subseq from] Beta-lactamase family protein n=2 Tax=Bacteroides fragilis TaxID=817 RepID=A0A017NG10_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Croceicoccus naphthovorans TaxID=1348774 RepID=A0A0G3XMN1_9SPHN ----LRQQLFAVARADKGRIGVAALDLSSGQTV-SILGDQAFPMASTSKIAIAATFLAGVD -AGKYQLDDKYPLMIPVASRSTAVAPVKPGMSLTARSLIELMITRSDNAATDAMLKAVGGP -AEVTKWMRSKGFNRFRIDRDIATLVRATGADQRDSAPPMEMVQLIAGLYKGQWLSGPSTD -VVIGAMTRTVTGSRRIKAGLPSGTSFGHKTGTLNN-TASDVGFVEMPDGRVVALAIYVTG -QG-GRPQRDARIAEITRTLYAGf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Alistipes provencensis TaxID=1816676 RepID=UPI0007ED4F40 --eSLERAVRAVTDSVRATVGVAVV-FGDGDTL-VVNNACRYPTMSVYKFHQALALLDDLD -RRGLPLTTRIPVRRSDLLPWSPLREACPEGGFTAAELLAYSVAQSDNNVCDVLFRFLGGP -EAVSRYIAGLGIGETVIVADEETMHRRTDNQYLNWTTPLAAVRLLELFRRGELLSAASGD -FLLKTMFATATGPDKLRGLLPPGVAVAHKTGSAFRDADNDIGIVRLPDGRSYSIAVFVMD -SREDDRTNAAVIARISRLVYDY- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A414IMN9_BACUN --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYICRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Erythrobacter sp. THAF29 TaxID=2587851 RepID=A0A5P9GW22_9SPHN ----LASKLRIIEAAAGGTLGAEIHDTGTGMGF-GLNRHMRFGHCSSFKMSLAAMALARDA -SGLVSKDRQVTWTEDDLMAVSPFTTERLAEGATISELAEATQKFSDNAAANILLREFGGP -QELTGFWRFLGDTVSRLDRIEPLVNNVPEGEIQDTTTPFAMARTVARITQGQVLPDTHRG -LLTQWMVDTRTGLRRVRSGLPEGWLAGDKTGTSLDSLYVDIGFVEPPNRAPLAFAAYYRA -RGTHEPAAEQVLARVGGVIADY- ->[subseq from] Uncharacterized protein n=2 Tax=Bacteroides TaxID=816 RepID=A0A0J9FBX5_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -ETVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter aquimaris TaxID=255984 RepID=UPI00135ED51F --nALEQTIAELADGSKGRIGVAAVDLSTGKTV-SVLGDQLFPMASTSKIAVAATFLEGVE -KGKWSLTSEFPLLLPRRSASSPRAPVYEGQYMKAIDLIEIMITRSSNPATDALLRVVGGP -EAVNDWMRRQGIDEFSIDRDIATLVRAQHIDTRDAATPNAILELLSGLYQGKYLSAESRR -VLLGAMSRTRTGKRRIPALMPASVKVSHKTGSLNN-TSSDVGILETPDGRAVAVAIYVTG -QG-SRLNREAKIAQIARALHDGy ->[subseq from] Beta-lactamase n=5 Tax=Akkermansia muciniphila TaxID=239935 RepID=B2UM78_AKKM8 ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A448LKC3_9FLAO --sELKKAIETILAHKKADVGVSIVTAGKKEVI-QINGNKPLPMLSTFKFPVALAVLHKVE -KGELSLQQKIYIKKEELLEYSPFKDKYPDGNLSLEDCIQWMVVYSDNNLTDILLRLIGGP -DYVQQFINS---KNIVIKNDEEGMHKDWDSQFINTITPNEATWLLEQFYTGKILNKEHTK -WLYTAMLNNATGAKRLKGKLPKDVKVAHRTGTSFTGAVNDYGIIELSDKKRIYIAVLVHD -TYETFENSEAIIADIAKAAYNHy ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011AFC0FB ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPQDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Tri-39 TaxID=1867714 RepID=A0A4Q1U331_9BRAD ---RLDSGIRTIEQGTKGRLGVGLIDLKDRKSW-SHRGSEPFPLQSVFKLPLAIGVLQAVE -AGKLKLDQTITVTRNDLSLHSPLAKAFKGERYPLRELLTRSTAESDNTAADLLLRLIGGP -QALTAILKDGGVSGISVDRYERVFQPATLTDKRDAASPEASIAFLEGLAKGTWLRDPAHA -ALLDIMLEAKTGPNRIKAGLPKGARFAHKTGLGPNHATNDIGIVTLPDGRRFAIAVYLAG -AQVGEIDREAAHAAVARLAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=E0WMX8_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A3A9B5K0_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTA-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGYNDIGFVLLPDGRTYSIAVFVKD -SKENSQVNSKTIADISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. FM1 TaxID=2484537 RepID=A0A3N2QN10_9SPHN ---ALERLVGQIADGSQGRIGVAAVDLVTGQQV-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWSLSSEFPLMVPVRSASSAVAPVRPGKYFKAVDLIEMMLTRSSNQATDALLKVVGGP -RAVNKWVRAQGIQEFQIDRDIATLVRAKQIDTRDSATPKAMVKLLTGLYQGKYLSEASRR -VILGAMERCRTGSRRIKALLPGTAIVAHKTGSLNN-TSSDIGVIKAPNGHAIALAVYVTG -QG-SRPAREAKIASIARTLYDGy ->[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8IHY6_9BACT ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN -FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCMEw ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A3R5UIP5_9BACT ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN -FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCMEw ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium HG15A2 TaxID=1930276 RepID=A0A517MTN7_9BACT ---ALAAQLQPLIDAHQGVVGVMVKDLKTGVEF-RHRVDEPMPTASLIKFPIMIATYQAIE -RGDLKLDRKLTLQEEDKVPGSGILTEHFEAGMPLKNAIHLMMAVSDNTATNLVIDQL-GL -EATNDLMESLGCPNTKLHAKVFRRDTRSQRYGLGSTTAAEMVKLLESLQNGELVSQEASK -LMREQMSAIGS-QAKFPRLLPDGVKLIHKTGSVS-AARTDAGIILSPHG-PIALCVLTEK -NKADDNAGEMLCSHIAKEVYDLf ->[subseq from] Beta-lactamase n=1 Tax=Croceibacterium mercuriale TaxID=1572751 RepID=A0A0B2BXX1_9SPHN ----LQQQIARLADGGQGRIGLFAVDLATGEEI-AVLGDQRFPMASTSKIAIAATFMEGVE -RGRWSLSSEFPLMVPVASRSTAVAPVRAGEHLSARQLIELMITRSSNPATDALLKAVGGP -AAVNDWVRRNGISEFNLSRDIATLVRATSIDTRDSATPRAMVQLLSGLHQGRFLSDSSRR -VILGAMERCRTGTRRIRALMPAGVTVSHKTGTLNN-TASDIGFIHAPDGRTIAVAIYVTG -QG-GRPGRDAKIANLARAIYDGy ->[subseq from] Beta-lactamase class A VEB n=1 Tax=Flavobacterium sp. 5 TaxID=2035199 RepID=A0A2N0HAA9_9FLAO ----LKSKIENILKGKKATVGVSIVANHYKDTL-NINGNEHLPMQSVYKFPIALAVLSEID -KKKFTLHQKIKITKNELPYWSPIRDEYPNGVLTISDILRYTVSQSDNNGCDILLRFIGGT -KVVEDYLSENKLTNISIKTTEEEMHQEWDVQYQNWATPIALNTLLIKSYDTQILSKENYK -FLWKAMTETSTGLKRLRGQLPKKTIVAHKTGLSGTAATNDIGVIVLPNGEPIFITVLVSD -STENAETNEKIISDIAKATWDYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI001230258A ---SLETQLKEAIKDKKAEIGIAVI-TDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI000EFFC4E3 ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLNSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5318 TaxID=2019666 RepID=A0A2N6LIE3_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVQR -PNND-PRAEKLIGSISKATYQQf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sp. BO-6 TaxID=2604537 RepID=UPI0013E13BE9 --tSLERRIAQLADGSNGRIGVAAIDLATGEEI-GVLADQYFPMASTSKVAVAATFLEMVE -QGKYSLTSEFPLLIPVPSAFSSAAAPVRQGEMPAHQLIEIMIARSSNPATDALLAAVGGP -KKVNDWMRRHGFKEFSINRDIATLVRAQHIDKRDAATPREMLRFLAGLYQGKFLSGSSRR -VLLDAMSKTRTGKRRIPALMPAEVEVSHKTGSLNN-TSSDIGIIEGPDGRAIAVAIYVTG -QG-SRAAREDRIAAIARALYDGf ->[subseq from] Beta-lactamase class A n=2 Tax=Luteibacter sp. OK325 TaxID=2135670 RepID=A0A2T5LGP2_9GAMM -------------------------------------------MCSTFKLLAVAAVLNRVD -KGSECLDRRIYYGRDVLLSHAPVTSLHADGEMTVGQLCDAAITVSDNTAGNLLLQAIGGP -DGFNVTMRAFGDTATRLDRTEPKLNIA--SGVLDTTTPEAMGQVAGRLLSGGLLMPTSVA -KLSDWLRAATPGLTMLRAGFPAEADAGDKAGRGTGGQNNDIAIVWKQGKKPLLVAAYYVN -SDMDDGQRNAVLAEVGRVVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhodococcus sp. EPR-279 TaxID=1813678 RepID=UPI0007BBD5DD ----------------------------------------------------VGAVLAAVD -AGALQLSDTRTITAADKVPESAVD-WEPGSVVTIADLASAALTESDNTSGNLLIREAGGT -AALTEFARSLGDTEFRLDRTEPELNTAIPGDPRDTTTPNSMAAGYRTLLDGDVLTAASRE -QLLAWMADTQTSDARFRAGIPDGWTSADKTGTGSYGVSNDAGLLLGPDGQRILVVVLSAT -TSEDSPAMNSLVSDATRQVVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Rudaea cellulosilytica TaxID=540746 RepID=UPI0003A8C511 ---ALQSRLAALAQRAPGTLGVAVLDLRSGTSW-RINAGRGYPMMSVFKAPLGAAVLERVD -RGKLSLDREITLTSVDLRPPGPIGGEIQAGHFSVRRLLDAAVSESDNTAADALVKLVGGP -TAVTTFLRAHGIEGIRVDRDERTLAHAFLTDPRDTSTPEAAVAFLCKLWRGELVSRTSTT -LMLEMMTHSPTVPNRLKGGVPAGAHLAHKSGTSITAAHNDIGILSWADGRTVIVAAFLTA -SPASEQERDAIFATLTRDV---- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. CBA7301 TaxID=2715212 RepID=UPI001435BFAD ----LETQLKEAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMA -KHKQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDVLFNYQGGP -DAVDKYIHSLGIKDCAIVGTETAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD -FIWQTMVECQTGQDRLVALLDKGVIVGHKTGTGDQIGCNDIGFVLLPDGHTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI00035E7BEB --dRLRSELTALANAHPGRVGICVRDEASPAIC--VNGEQRFSLQSVMKVVVAAAVMQAVD -DRRIALGDRLTIRRGDLSVIQPIADIVAERGTSIGDLVSRAVVESDSAATDVLISHLGGT -KAVQAFLDEAGLQGIRIDRTERELQTAYLKDPRDTATPIEMVGFLHRLATGQLLSASSTA -HLLEVMNRTVTFPDRLRAGVPSGWTIGHKTGTSQNGVTNDVGILTAPDGTHVAVAAFVAE -SRAGKDERAATIAAA-------- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q45115_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDRHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000B8E3111 ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN -FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDQVIASMARWLCL-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0007D945B0 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KEFQQALIHRGDHISNPQRPEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE -LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium BRH_c42 TaxID=1734407 RepID=A0A117S421_9SPHN --tSLERRIAQLADGTRGRIGVAAIDLSTGRQI-AVLGDQLFPMASTSKIAVAATYMEMVE -QGKYSLTSEFPLLVAVGSASSAVAPVRKGEHMAAIDLIELMITRSSNPATDALLAAVGGP -AKVNDWVRRQGIREFSINRDIATLVRATHIDRRDAATPRAMVELLRGLYQGKYLSAESRR -VILGAMSRTSTGKRRIPAQIPLGAQVSHKTGSLNN-TSSDVGIIETPDGRAFALAIYVTG -QGAR-AAREERIAAIARALYDGf ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000C9A686A ------SSVRKLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN -FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCMEw ->[subseq from] Beta-lactamase n=3 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A2N8IPJ1_9BACT ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. KK2 TaxID=1855727 RepID=UPI00097E6754 ----LDNRLFEIWRAFPGKTGIAVQRIDGEWAL-AQRGNELFPQQSVSKLWVTLAVLDAVD -NGRLTMDQKVRIGPEDLTLHQPIAARVQSQGMSVRELIETAITQSDNTANDSLLRTVGGP -DAVRRFIDKKDLGAIRFGPGERLLQSAYRADPPDGASPAAIAKALSRLARGTLLSPESTQ -YLLGVMSRTKSGPQRLKAGLPAGWTFLHKTGTGQRGGYNDIGIATAPDGTRYAIVVMMAE -ASSPVPARMATMQSVSRAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SPI0_9BACT --sELKNRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYICRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. NAP1 TaxID=237727 RepID=A3WF43_9SPHN ---SFEQRIAELADGDRGRIGVAALDLATGESV-AVLGDQLFPMASTSKIAVAATYLEMVE -QNKYSLTSEFPLLIPIRSASSPAAPVRRGNYMPAIDLIEIMITRSSNPATDALLAAVGGP -EKVNDWMRRQGITDFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLYRGDFLSDQSRQ -VLLGAMSRTVTGRRRIPANMPDEAVVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG -QG-TRRNREARIASIARALYDGf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingopyxis sp. PAMC25046 TaxID=2565556 RepID=A0A4P7RW00_9SPHN ----LDDRIFQLWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD -QGRLTLDQRVRIGPEDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -DAVRAFIDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE -YLLGVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TSASVPARMALMQAVSGAVADY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. LC363 TaxID=1120705 RepID=A0A095B9Q1_9SPHN ----LDDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD -QGRLTLDQRVRIGPEDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -DAVRAFIDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE -YLLGVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TSASVPARMALMQAVSGAVADY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A1W6AL31_PSEAI ------------------------------------------------KVMAAAAVLKXSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGXP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter tepidarius TaxID=60454 RepID=UPI000A3BC79A ---SFSQRIAELADPSQGRIGVAAVDLATGEQI-MVLGDQLFPMASTSKVAIAATFLEMVD -KGRYSLTSEFPLLLPERSASSPKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP -AAVNDWVRRQGIENFSINRDIATLVRAYHIDKRDAATPRAMTQLLAGLYRGDFLSDESRR -VLLGAMSRTVTGKRRIPAHIPLEARVSHKTGSLSN-TSSDIGIIECPDGRAIAVAIYVTG -QG-SKLAREERIAAIARALYDGf ->[subseq from] Serine hydrolase n=2 Tax=Phenylobacterium sp. LX32 TaxID=2170551 RepID=A0A328AKA6_9CAUL ---ALQEKIEQLAERYREPVGIAITDVSARWTA-QVAGDEVFPQQSVSKLWVALAVMHAVD -RGQLRLDQPVTLTKEDRSVYQPITAKIRGPNTSVYELLKYQLTESDNAANDKLIAEVGGG -EAVSRVMAEKGLEGLGRGETERDLQTAYLANPGDGAKPAAITNALAALHRGELLSPQSTE -AMLDLMAQCRTGSSRLRAGLPSGWSIAHKTGTGPSVGINDVGLITAPDGRTYAVAVMLRQ -TRHPVGARQALMQAVARAVVDYw ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium sp. CAP-1 TaxID=2676077 RepID=UPI0012BB326F ---KLLAEFARFATLSDGTVGIAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD -AGDLRLDDQLALDPALASEGIAWMFSRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP -QAITAFVTRLGVTGLRVDSDTAHLLYTFATEPEDTSTPTAMLDLMTAYEEGRALSPASTE -RFFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GVGNDVGIVRLPDGRRFAVVVFVMK -DSKGHVSRDRIIAEAARAAYDYf ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SDB7_9BACT --sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium lentum TaxID=145287 RepID=UPI000834391F ----VQQQLAGIVAQSRGRIGVAAVDLDGGGQV-MINGDQPFPMASTAKVAIAATFLSQVE -AGRLRLDQNLPMMIRERGPRSAVAPVRQGPIYAAQSLMELSITHSNNEATDGLLSAVGGP -QVVNAWLTRAGITGQHLDHTMATLVRARVIDVRTASTPRAMVALLGAIDRGNALSPQSRA -ILLDTMTRTVTGSKRMRAGLPEGVVFAHKTGTLS-GVTDDVGIIRLPDGRHLAVAIFVTG -PEG-HSAHGAMIAQITRTLYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID=UPI0013DCE502 ------------------------------------------------------------- -----------------------------TDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRFVVIYTTG -SQATMDERNRQIAEIGASLI--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus sp. 47.1 TaxID=1929484 RepID=UPI0008A51EFE ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KEFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE -LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. PC22D TaxID=1962403 RepID=A0A2A8I184_9SPHN ---AFEARIASLAEASQGRIGVAAMDLSTGRVI-DVLGDQRFPMASTSKIAIAATFLEGVE -KGRWSLTSEFPMMMPVRSESSAVAPVRAGEYYTAGKLIELMLTRSNNYATDALLRVVGGP -AAVNAWVHRAGITDWQIDRDIATLVRAEVIDSRDSATPMAMVQLLAGLHEGKWLSDSSRQ -LILDTMGRCLTGRRRIVANLPTEARVAHKTGSLFN-TSSDVGIIETPDGRAFAVAIYVTG -QG-TRLKREARIASIARALYDGy ->[subseq from] Beta-lactamase class A n=3 Tax=Nitrospirillum amazonense TaxID=28077 RepID=A0A560J239_9PROT ---ALQARLDRLAHDFPGQAGIAVRDGLTGAEV-GVKARGRFPEQSVFKLTVAIALLDLVD -HGRMDLAQKVTLYPKDRSVWQPLAKNITPAGTTLDDLMARMVADSDNVAADTVLRLIGGP -AVVQAALTARGLDGIRVDRDERHLQSAYLSDPRDTAQPATMALLLDRLDKGALLSPASTR -RLLDILDHTTTQPNRLKAGLAAGWTVAHKPGAGPTLANNDVGLMTAPDGHRYAVAVYVAS -VQGPRERADAFIASVARAVVESw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. 1.A.5 TaxID=2044604 RepID=UPI000C0BFA74 ----LKKKIEQIISQKNSVVGVSIIGNNGRDTL-SILGDKKFPMQSVFKFHIALAVLDLVD -KGKLSLDQTVKVGKKDLMTWSPLRDENPNGGFTIEKLIQYAVSHSDNTACDVLIKLVGST -KDVEKYFKKNNIQDIQITYNERDMQAKWENMFQNWTTPKAASKTMMLFYEKEPISKNSYF -VFWRTNFETTTGEKRIKGKLPVGTHVAHKTGWSGTAAVNDIGIVVLPNDQHFYISVFITE -SKENFDSNEELIADIAKAAYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0M4FFL9_KLEPN ----------------------------------------RFAMCSTKKVKAAAAVLMKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AM16-24 TaxID=2292002 RepID=A0A414ZCQ7_9BACE --kELEQPIGQVLKDKKATVGVAVLVNDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYAGGI -DKVNSYIKSLGLKDFNLAANEELMHRDVATQYQNWSTPEAVVRLLNIADKQTLFAAEYKD -FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Halomonas axialensis TaxID=115555 RepID=A0A455V9W0_9GAMM ------------------------------------------------------------D -EGLLAPDTEVSFDESALVTYSPVTEQYAGHQMTLFELCDATMTTSDNTAANLILEALGGP -EAITAFARRLDDSVTRLDRFETELNEATPGDERDTTTPNAMLATLETLVLGDVLTPESRQ -QLQDWMKGNAVADGLFRAAMPFDWVIADRTGAGGYGSRSITAIIWPPEQAPTVAVFYPHR -NRRSAQRSHCV------------ ->[subseq from] class A beta-lactamase n=1 Tax=Myxococcus sp. AM301 TaxID=2709664 RepID=UPI0013D75B33 --gELGERLARAVAPAEGPVGVAVVDDADGAAV-VLGGGRRFPMQSVFKLPLAMAVLDAVD -RGELRLEQRVRVEPSDFVSHSPLRDAHPDGVLTLGELLRGAASGSDGTAADVLLGLVGGP -VAVTRYLRSVKVEGVEVAVTEKEMGRDPKAQYRNWATPEGAAALLLAVEAGRGMSADGRR -HLLRLLTETPTGPNRIRGRLPAGTPVAHKTGTSRTAATNDIGLVTLPDGRRLVVAVFVSE -SPADDATRERVIADVAREAFDFw ->[subseq from] Uncharacterized protein n=1 Tax=Bosea sp. Tri-44 TaxID=1972137 RepID=A0A4Q1V5W8_9BRAD ---RLDSGIKTIEQSTKGRLGIGLIDLKDRKSW-SYRGAEPFPLQSVFKLPLAIGVLQAVE -AGKLKLDQKITVTRNDLSLHSPLAKAFKGERYPLRELLARSTGESDNTAADLLLRLIGGP -QALTALLRDGGVSGISVDRYERVFQPATLTDKRDAASPDASIAFLEGLAKGTWLRDSTHA -ALLDIMLEAKTGPNRIKAGLPTGARFAHKTGLGPNHATNDIGIVSLPDGRRFAIAVYLAG -AQVGEKEREAAHAAVAQLAVE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium sp. G1-14 TaxID=2003121 RepID=UPI000B490DA1 --nSLRKELHQIIATKNATVGISMKGIETKDTL-SINGHLNAPLMSVFKFHIALATLNLVD -QGKLSLSQKFFIKKEDLHAWSPIRDEFPNGNLTLDQLLRYTVSHSDNNGCDILLDLIGGP -ETVQKFINKQGIKDFTIKVNEQEMR-IWENLYSNTTTPLASTELLEKFYARQVLKKNSTK -YLYQLMVECSRGLTWMKAGLPERTELAHRTGISDRAAMNDVGIFKLPNVNHVVLSVYLKD -ITEEREVTEKIIADITKAIWNYy ->[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=Bacteroides TaxID=816 RepID=A0A414E6J5_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANNKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Francisella sp. FSC1006 TaxID=1547445 RepID=A0A097EMU0_9GAMM ---SLDDSFKDLENKYNGKLGIYSTD---KSSI-NYNENYYFPICSVFKFLLVGAILEKDM -HNKGFLDKKITITQKDISTYAPVTGKNISKDLTISQLCFAAI-LSDNPAANILVKELGGI -DKLNKFIKKLGDNDTNIKNIEPKINHTKPDSTINKTTPKAITNDIYKIAFGNILDEKHKE -IFIKYLQDNNTGVNRIAYNTPKNWIVGDKTGTCGYGATNDIAIIWPQNAEPFALGMMYTD -PTKKAPSSEKIIQQATKLVI--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5W4S6_ECOLX ------------------------------------------------------------- --------------------------------MFLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAK------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0009BF3A38 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KEFQQALIHRGDHISNPQRPEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE -LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. Alg231-14 TaxID=1922225 RepID=UPI000D553C37 ---SFEQRIAELADGDDGRIGVAAMDLATGEQI-MVLGDQLFPMASTSKIAVAATYLEMVE -QGRYSLTSEFPLLIRVRSPSSPAAPVREGEYMPAIDLIEIMITRSSNPATDALLAAVGGP -QAVNAWMRRQGINDFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLYRGDFLSDQSRQ -ILLGSMSRTTTGRRRIVANMPSEARVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG -QG-SRLARERRIAAIARGLYDGf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. AAP83 TaxID=1523425 RepID=A0A0N1C5A7_9SPHN ----IQQQIAAIAAEGRGRIGVAAMDLDGGGQI-MVNGDMPFPMASTAKIAVAATFLEQVE -KGAHRLDQEFPMMLPVRETISPVAPLRAGTVLTAQSLMELMITRSHNEATDGLINAVGGI -ENINYWLTRNGIAGQRLDHTMATLVRARVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLS-GVTDDVGIVRLPDGRHLAVAFFVTG -PEG-HAVHAKLIARMMRVIYDGy ->[subseq from] TLL2115 PROTEIN n=1 Tax=Synechococcus elongatus TaxID=32046 RepID=UPI000181CD26 ---NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD -EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA -AELNQQFQEWGLENTVINNPLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMVYQAf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. LM 6 TaxID=1896196 RepID=A0A1D7NHC6_9SPHN ---SFEQRIADLANPAQGRIGVAAIDLATGEEI-AVLGDQLFPMASTSKVAVAATYLEMVE -KGRFSLTSEFPLMMPVASAKFSTAKAPVRAGMPAIDLIEIMITRSSNPATDALLAAVGGP -GVVNDWMRRQGIKEFSINRDIATLVRAYHIDKRDAATPRAMVRLLAGLYKGEFLSEQSRQ -VLLGAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDVGIIECPDGRTIAVAIYVTG -QG-SKQAREERIAAIARALYDGf ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides uniformis TaxID=820 RepID=A0A4Y1VJW6_BACUN --sELENRIDSLLNGKKVTVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQNISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISLSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5273 TaxID=2019663 RepID=A0A2N6L0P6_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGTLMAMVSQGNLLNMASRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -SNND-PRAEKLIGSISKATYQQf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A2L1J159_ACIBA ------------------------------------------------------------- -------------------------------TMTLAELSAAALHYSDDTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLASAAR------ ->[subseq from] class A beta-lactamase n=1 Tax=Dyella ginsengisoli TaxID=363848 RepID=UPI000A00FB82 ---RLQQALTQLASKAPGVLGVTIVDLNTGVRT-RINANRAYPMMSVFKAPVAAAVLAQVD -AGRISLNQEVTVDRQDVVSGAAVPSQFKGEHFTVDRLLVAAVSESDNTAVDALIRQVDGP -RVVTDFLRKHGIDGMRVDMGEGDIGRAYLDDPRNRTTPDAAANFLEKLWTGQLLSTRSTK -RLLGLMYGQTV-PSRLRSGLPAVVRFADKCGTSYTAAFNDIGIMTGPDGHTVIVAAFLTA -SRADKKARNAFFAKIGKDVADAy ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=D4WB00_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIPYPLMSVFKFHQALALADYMG -KQRQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANNKIIADISRIVYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar2 TaxID=2004468 RepID=A0A1Y0H7F3_9BACT --------LAAIEARSQGKLGAAVV-TAQGAHY--LHQDEKFSLQSVMKLMVAMAALEQVD -RGQWRLDQSFEFKRSDLSLHQPITQRLGRREITLDECIELMVTESCSGAADFIIRRLGGP -EKVNAFLVKHDIQGMRIDRLERDLQTRYLADPRDTTTPAAMAKLLQKLLQGQLFSPTSTR -YLLGVMERTATGQDRLRAGVPAGWTVGHKTGTSSAGATNDVGIARNKAGEWVILVALLRE -STLAPRDRDRILADVARA----- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. LC363 TaxID=1120705 RepID=UPI00055C0AB5 ----LDDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGDELFPQQSVSKLWVALTVLDAVD -QGRLTLDQRVRIGPEDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -DAVRAFIDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE -YLLGVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TSASVPARMALMQAVSGAVADY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI0004523C26 ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLREIYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A1C7GYN1_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTA-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -EAVNRYIHSLGVRECAIVGTETAMHEDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRMVALLDKKVTVGHKTGTGDRNGYNDIGFVLLPDGRTYSIAVFVKD -SKENSQVNSKTIADISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. OV259 TaxID=1500286 RepID=UPI00055646CF --qDFKKEINSITKDKKATVAVSVTGIDFPFEFnNKNSSKKLPMLSVFKFHIALAVLNEVD -KGKLKLDQKIFIKKTDLLEHSPIRDNFPKGNMPLSELIKYTVAQSDNNGCDILLRLIDGT -ETVQKFMNEKGVKNFQIKYNEEGMHKGKEYLYANYTTVASLNSLYKKFYEKKILSRKSTD -FLMKIMLETSTGTNKLKEQLPKGIPIAHKTGSSGKEAENDSGIITLSNGKHYAISVFVID -STETEAVNCKMISDISKAVWDQf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10 TaxID=1797944 RepID=A0A1F9VSL7_9BACT ---AMVESLDKLSRSYRGRVGIYIRDLETGKTW-AYNAEKLFPSASLIKVPIMAAVFEKIK -LGEFTLDTQIKLTRPSRVGGSGSLKWVREGTLSVMEIVYKMITESDNTATKMLIDQV-GM -PYLSEAFKKLGLEHTNITPEGMSLSS-YRVKRENYTTPREMASLLERIYAGELVNRESSE -FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE -AP-NYTTAKNFISKVAKLTYRYy ->[subseq from] Serine hydrolase n=2 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NV03_9BACT ---RLEQELLRLSNLSAGKVGICAVHLESGRTI-TQNGKDHFPMASSYKVAIATQLLTRVD -SGSVTLDQLVPITKTDFHPGSGMLSERFNSTLSVRSLLELMLLISDNSATDICLRLAGGP -AAVNACMKRLGVDGLQVNRPTAWLIAAFENDLRDTSTPEAMTLLLTKLYTQPILKPASKT -LILDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGDGHVAISVFVKS -SKKEGAVRERTIAEVTRTIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Legionella fallonii LLAP-10 TaxID=1212491 RepID=A0A098G2M7_9GAMM ---ELAKKIDTIEKKSKSVIGITAIYIEKNKIV-GHNSNKRFFMASTIKLPIALAFLHRVD -EKQDSLNRVIKMDMKNSVPGSGSLHHLFEKKMSMQQILKYMMRNSDNSASDTVLHAVNGP -EYVKKRMDALGFKNIYVNRSILEMFLRFENDTRDTTTPEDMAKLLVKVYKKQALSEASTK -VLMNIMEQCRTGRSRIRGLLPGSVKVAHKTGTWAYRFASDVGIITLPNNGHIAIAVYVKS -QSASDYPRSRAIALASRAVYDHf ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter sp. SLTP TaxID=2683266 RepID=UPI0014120282 ---NWQQRIAELADPAQGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATFLEMVE -QGRYTLTSEFPLMMPVASAYSSTKAPVRAGQMPAIDLIEIMITRSSNPATDALLAAVGGP -AVVNDWIRRQGITNFSINRDIATLVRAVHIDTRDAATPRAMVRLLSGLYRGDFLSDQSRQ -VLLAAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIECPDGRTIAVAIYVTG -QG-SKEAREERIAAIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Odoribacter laneus CAG:561 TaxID=1263089 RepID=R5VPE2_9BACT --kDIEIQIADFVKDKKATVGVAVL-TEDDKII-QYNNSVHFPLLSVFKFHVALAVLNKLD -KQHIDLDSTIQIKASQLRAYSPLRDKFPNQDLSWKELLQYSISLSDNNACDILIDSAGGI -AAINKYIQKLGIKDFNLSATEDFMHQGIKNAYLNWSTPLEVVRLMKLAYTKELFSAPYKD -FLWKTMLETSTGANKLKGLLPENVLVGHKTGSSDRTADNDAGLVLLPHGKSFYIAVFIMD -SQETDQTNAAIIAHISKLVYE-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0009C0BE4E ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNTP ---TSELNKKIVISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KEFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE -LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A286SCJ1_KLEPN -------------------------------------------MCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVG--------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides oleiciplenus YIT 12058 TaxID=742727 RepID=K9E3G2_9BACE ---GLEQQIEQVLKDKKATVGVAVLANDTIIA--LHNNQIHFPLFSVFKLHVALAVLDKMD -KEHVSLDSIMEIKAAQMLPYSPLRQKFPDQDISLRELLEYSISLSDNNACDVLIDYTDGI -EKVNSYIKSLGLKDFNLAANEDLMHRDVATQYQNWSTPEAVVRLLDIADKQTLFATEYKD -FLWQILKETSTGTDKLKGQLPPDVIVGHKTGSSDKTADNDAGFIILPDGREYYITVLVME -SQENDQENAAIIARISKIVYD-- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-2100 TaxID=1954172 RepID=A0A1Z4GS59_9CYAN --------VQSLTAANNLAPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVASKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVSMRSRD -RLLDIMRQTQK-DTLLPSGLGAGATIAHKTGDIGT-MLADAGLVDIPSGKRYIAAVMVQR -PNND-PRAEKLISAISRAAYQQf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WTI7_9BACT ---ELKKKLEHVDSSVQSEVGIGVLDLSSGESW-FLNGEQRFPMQSVCKVPVAIAILKLVD -DGALSLGQSVTINPEQYAPWSPLRDELKGGSFTVRNLLERSVADSDNTAVDVLIELAGGA -GKVDAILKAMGIRGVRVDRRERDLQTKFLSDPRDTATPEGMVHLLSQLYQNKLLSPSSTQ -LLLQIMTDTPYGQYRLKAGLPPKWSLAHKTGTGPNTGTNDAGLACAPAGQCFALTVFIAG -SKVPLQNREALMRDVAAAVT--- ->[subseq from] Cft2 n=1 Tax=uncultured bacterium AOCefta2 TaxID=654977 RepID=D6MLX4_9BACT ---DLSQRLAEIARRAGGQVGVSVMNIENGDSA-DFNGDEPRSLYSVFKFPVAVAVLKDVE -TGKLKLDQKVAVKKSDLSGTAPSSSNRWQNMYTVQQLLEFAMIESDNTAVDKLLTLVGGP -STVTKQIQSLGISGIEMAADSREAA--KLADHPNTGSANAIVRLLAGLQKGEVLKPAERT -VLWDMMQRATTGVKRLRAGLPARTVLMHKTGTGPDSGTNDVGIINLPDGGHLAIAVLINK -STLSSASQEQVIAAIAAAAWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D6A4H7_9BACT --qDLKGLLAPLINRHRGEVSVAVKHLATGQSF-SHRADQPMPTASLIKLPIMIEAYRQAE -AGTIDLDLTITLAQADKVPGSGVLTPHFSAGLSLRDAVHLMMTVSDNTATNLVIDRI-GL -RATTDTMERMGCANTKLHSKLFRRGTRSKQFGIGSTTANEILTLLEKLHASKVVSKKASE -AMLGHMLACTD-KDKFPRFLPPGTKLAHKTGSVSS-VRCDGGIIYAPGGA-VAVCVLTKN -NRDQDNAGNRLCARIAITAYRHf ->[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis alaskensis TaxID=117207 RepID=Q1GWS4_SPHAL ----LQDRIHALWSAFPGKTGIAVQRIDGEWTL-SHRGGDLFPQQSVSKLWVALTVLDAVD -QGRLTLDQRVRIGPEDLTLYQPIAARVRAEGLSVRDLIEIAITQSDNTANDSLLRTVGGP -DAVRRFIAKKDLGAIRFGPGERLLQAAYLANPPDGASPTAIANALTRLARGALLSPESTE -YLLGVMSRTKSGPRRLKAGLPADWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TSAPVPARMELMQAVSSAVAAY- ->[subseq from] class A beta-lactamase n=1 Tax=Cryobacterium sp. Sr39 TaxID=1259198 RepID=UPI00141BB793 -------------------IALSAKNVRSGRQI-NHRATEPVPMCSLFKVLAVANLLRLRG -YEDQYWSTPISFTAADVVVNSPVAAASTSMTMTPNQMADAALRFSDNTAGNLLLRELGGP -ATITQFAQALGARRTRLDRIEPELNEGLPGDVRDTTTAEDMVAIMEALLIDGDAGQLARS -RLQDLMLRNTTSGTRARAGLSEPFELADKTGAGNYGIVNDAGVLWQGQRQTIAMCILTRT -EVASAPNNNDVIADATRLIVSEf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. CCP-7 TaxID=1979270 RepID=A0A437LWC0_9SPHN --qRLDARLEAYAQRKDIRVGIAAIHLESGATV-SVNGAEAFPMASAYKLAAVLTLLHQVE -QGRFTMTQMIPVDDALRVQSGGISTSMPHAGLSVANLIDLTITRSDNTAADMVTQMVGGP -QAITAWLKSVGIEGQRVDRDVAGLIFAFIADPRDSSTPDAMVALLTKLQQGKLVNAEHTA -WLIDVMAHTVTGAKRVKGLLPPRTVFAHKTGTLV-GICADVGILTLPGGGHVAIAVFVKS -HD-DGAKAEAIIAEVGRTIYD-- ->[subseq from] serine hydrolase n=1 Tax=Croceicoccus sp. H4 TaxID=1783232 RepID=UPI000AE4814C ----LRQQLFAVARPDKGRIGVAALDLSTGQTV-SILGDQSFPMASTSKIAIAATFLAGVD -KGIYRLDAKYPLMIPVASRSTSVAPVKPGMELTARSLIELMITRSDNTATDAMLKAVGGP -AEVTKWMRGKGFQRFRIDRDIATLVRATGADLRDSTPPDEMVRLIAGLYKGEWLSGDSTD -VVIGAMTRTVTGSRRIKAGLPSGTNFGHKTGTLNN-TASDVGFVEMPDGRVIAMAIYVTG -QG-GRPQRDARIAEITRTLYAGf ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011CD6066 ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unicellular cyanobacterium SU3 TaxID=1982589 RepID=UPI000B3DD822 --eNLQKKIEKVLKNKSATVGVAISGMDPSDTL-SINGDKRLPMQSVFKYHLALAVLHEVD -QGKFGLEDNITIDKELVDAWSPLRKKYPEGAVILAEILEYTVSLSDNLGCDILFDLIGGP -TVVEAYLHKIGIKEITIVHKEIDMQAKWERQFENWTTANTANLSLKLFFEENLLTDKSYS -FLLEILKGTKTGLKSIRGLLPKETVVAHKTGSSGTGALNNIGIVFLPDNSYFYISVFVSD -SKESNDTNQKIIAEIAKLAWDYf ->[subseq from] Beta-lactamase n=1 Tax=Flagellimonas eckloniae TaxID=346185 RepID=A0A0Q1BWV6_9FLAO --qTLKREIYEILQDKDATVGVAISGQNPKDTV-TINGNVHLPMQSVYKYHLALAVLDQVD -KEKLSLEEKITLTKKDLDNWSPIREKYTEGTLTLAEIIEYTVASSDNVGCDLLFKLVGGP -KTVEDFLHNSGISNVAVRYDEEIQQANWDLQYENWTTAKASNKALKVFFENAQLSKESHA -FIWKTMKSSWTGANCIRGHLPKNTVIAHKTGHSGTGAQNDVGIVFLPNGTYFYLSVLVSD -SKEDSKVNEKIIADIAKLSWDYf ->[subseq from] Serine hydrolase n=1 Tax=Bosea sp. Root483D1 TaxID=1736544 RepID=A0A0Q9I8N1_9BRAD ---ELESKLKELAASHPGRVGICAQSA-GDKPV-CVNGEQRFSLQSVMKLVVGAAVMRAVD -EGKMRLDDKVTLRREDLSVIQPLADIVLKDGSTIEDLVRRAVVESDSAATDFLIARLGGV -GAVQTLLDAAELHDIRIDRTERELQTAYLSDPRDTATPLAMVRFLRKLAAGQLLSPASTK -HFLAVMSQTVTFPDRLRAGAPAGWTVGHKTGTSHNGVTNDVGLLTAPDRGFVAVAAFIAE -SRAPAPARAAVIAEAARRVTGAy ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0006990017 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGGRFAFASTYKAISSGILLQNTP ---TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KGFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTLNHLLQSENMSKANLE -LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3D1A6M8_9BACT ---EMVEDLEKISRSYRGRVGIYIKDLETGKTW-DYNSDRKFPSASLIKVPIMAAVFEKIR -AGALSLDTQIRLTRGGRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATKMLIDAV-GM -DYLSSAFSAMGLEQTNITPEGMSLSSR-PVRRENYTTAREMGSLMERIYAGELVSREASE -FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-SCHDVGIVFSPRGD-FVIAVLTSE -SA-NYTMAKNFIAKVAKLTYQYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella sp. BN140058 TaxID=1892855 RepID=A0A4P6FT33_9SPHN ------------------------------------------------------------- -------------------------------GVSARTLMEQMITRSDNRATDLLIARLGGP -AEIHAWLRAHGLSGIRVDRTIAQLLAARRRDVRDSSTPTAMLRLLRTIDGDEALSPASRR -ILLDMMSRCRTGSNRMRALLPAGTKVEHKTGTLS-GYTGDVGFVTLPDGRRIAVALFARG -GV----NRPAVIASAARTIYDAf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Colwellia sp. 20A7 TaxID=2689569 RepID=UPI00135727ED --eSLKQQINSLLEGKNATVGVAILAGDGSEYI-SINGNKKLPMQSVFKYQLALAVLDQVD -KNNLSLSDRISISPKDLDNWSPIRKEYPDGALSLAEVLKYTVAYSDNVGCDILFNIVGGT -KVVEAYLHKQGIMDVAIEYDEITQQLVWDRMYENWTTANAAIAVLKLFYENKLLSQNSHQ -FLWDTMKISGTGKDKIKGLLPKGTIVAHKTGSSGTGAENDIGIVFLPDGTHFYISVLVSN -STEKSAVNKKLIADVSKVTWDYf ->[subseq from] Beta-lactamase n=1 Tax=Croceicoccus ponticola TaxID=2217664 RepID=A0A437GZ80_9SPHN ----LKQNLFAVARPDKGRIGVAALDLSTGQSV-SILGDQSFPMASTSKIAIAATFLAGVD -KGIYRLDSKYPLMIPVASRSTSVAPVKPGMELSARSLIEMMITRSDNAATDAMLKAVGGP -AEVTKWLRAHGFQKTRIDRDIATLVRATTVDVRDSTPPEEMVKLVAGLYQGQWLSQSSRD -VVIGAMTRTVTGRGRIKAGLPTGTSFGHKTGTLNN-TASDVGFVKLPDGRVIAMAIYVTG -QG-GRPQRDARIAEITRTLYSGf ->[subseq from] Class A beta-lactamase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A515A3U7_9BACT ----IEQELLRLSNLSAGKVGICAVHLESGKTI-TQNGKDHFPMASSYKVAIATQLLTRVD -SGSLSLAQLVPIVKTDFHPGSGMLPNSPNSDLSVRSLLELMLLISDNSATDLCLRLAGGP -AAVNACLKRLGIEGLRVDRPTAWLIAAFENDLRDTSTPEAMTLLLTKLYTQPVLKPNSKA -LLLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGDGHVAISVFVKS -SKKEGSVRERTIAEVTRTIYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Saprospirales bacterium GYS_P2D TaxID=2692196 RepID=UPI001359A01A ----VQSAIEEMIKSYDATVGVSIYEPKSGDQI-SVNGDRHLPMQSVYKLHLALTVLKDVD -AGICSLSDSIQITPAHIEQWSPLKKKYPNGAITIAEMMEQTVAWSDNMGCDILFEMVGGP -AIVEKYMRDIGITDVAIRYPEIIMQSDWEIQYLNWSTADAITLLLQKIYTNKMLSETSYD -YLMETLIGTQTGTKSLRGLLPEGTTIAHKTGQAGRGAVNDVGIIFLPDGSPLYISVLVSD -SREKLDDCYHIIAQTARIAWDHy ->[subseq from] Beta-lactamase n=1 Tax=Legionella tucsonensis TaxID=40335 RepID=A0A0W0ZPA8_9GAMM ---ELIKKIKDIEQKSNTVIGLAAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRMIRMDSRNSVPGSGALHYLFEKKISLEQILMHTLKNSDNSASDALLQAVNGP -QYVAKWMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPDDMAKLLVKLYKKQVLSESSTD -LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] Penicillin-binding protein n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=A0A0M0SH08_9CYAN ---SLKTNLQSLASANNLTPGVFVVDLENGSYV-DINASASFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMEKEMMVGGSGDMRNKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVNQGNLISMTSRD -RILEIMRNTVR-NQLLPAGLGQGATIAHKTGDIGS-MLADAGLVDLPTGKRYIVAVMVKR -PNND-PSAEKLIGSISKATYQQf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. FSY-9 TaxID=1908524 RepID=A0A437N0Q3_9SPHN -----ETRLAHLADASNGRIGVAAVDLGSGQGV-SVMGDQPFPLASTGKIAIVAAFLEGVD -QGRYRLNDRYPLMVPVPSRSTAVAPVRPGAMMSAEQLIELAITRSDNHATDALLAAMGGP -QVVTRWLRRVGVSGIRLDRDIATMVRARSIDLRDSTTPQAMAVLLAGLYQGQWLSAQSRE -VLLGAMRRCVTGIHRMKALLPDDALIGHKTGTLSN-TSSDVGLIRTSDGRTLAVAIYVTG -QG-GKPGREQRIAAIARALYENy ->[subseq from] Beta-lactamase n=1 Tax=Odoribacter laneus YIT 12061 TaxID=742817 RepID=H1DJM3_9BACT --kDIEIQIADFVKDKKATVGVAVL-TEDDKII-QYNNSVHFPLLSVFKFHVALAVLNKLD -KQHIDLDSTIQIKASQLRAYSPLRDKFPNQDLSWKELLQYSISLSDNNACDILIDSTGGI -AAINKYIQKLGIKDFNLSATEDFMHQGIKNAYLNWSTPLEVVRLMKLAYTKELFSAPYKD -FLWKTMLETSTGANKLKGLLPENVLVGHKTGSSDRTADNDAGLVLLPQGKSFYIAVFIMD -SQETDQTNAAIIAHISKLVYE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5HSW4_9SPHN ---KLLAEFTRFSTLSDGTVGVAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD -AGEVRLDDQLALDPALASEGIAWMFNRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP -QAITAFVTKLGVTGLRVDSDTAHLLYAFAMEPQDTATPTAMLDLITAYESGRALSAASTQ -RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAVVVFVMK -DSKGHVSRDRIIAEASRAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLZ6_9BACT --sELENRIDSLLNGKKSTVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pla175 TaxID=2528009 RepID=A0A518DAL2_9BACT -hdALQDAVAQLIKLHRGVVGAAAKQLDTGESF-AWNADQPMPTASLIKLPIMLTAYRQID -AGELSPDATIELRKQDKVPGSGVLSEHMSAGFSLRDAIELMIVFSDNTATNLVIEKT-GL -PATSALMRKLGYPETQLHSKVFLRETRSQKYGLGSTTAADMIRLLESLYKGDAASSESCE -AMLGHLRRCDD-RSKVPRYLPEEVEVAHKTGSVS-ATRCDAGIIESKGG-PLAFCILTTD -NAGAENEAELLAAAFGKTLYDHf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pla175 TaxID=2528009 RepID=A0A518DAL2_9BACT -------------------AAYAIADAANGELLwGMNDSEARDPASVTKIMTAHLVLKLAE -SDPEVLDEEIVFSTVADETPGSTSGVRAGETVTVRELLYGLMLPSGNDASVAFAEHFGDG -GPYEGFIRAMNAEAKRLGMKETGYNTSGLTAKGHVTSARDMARLAHAAMKSPVLR----- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=3 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A411SPD6_9BACT -------SAVQLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRQEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] CblA-3 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C145_9ZZZZ --sELENRIDSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKXYIAAFVMX -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter seohaensis TaxID=266951 RepID=UPI000C226B71 -heRLEARLREIGGTFSGEVGIAAVEVASGATM-AYNGDRPFPQQSVSKLWVALTALDLVD -EGALDLSEPAAIRREDLTVYQPIRDIVRTRGTDYRDLMERALTQSDNTANDRLLRRVGGP -QAVDAFIRRKGIEGVQFGTDERSKQSDYLHDPIDGASASAMAQALARLARGELLSPRSTK -FILSTLENTKSGPKRLKGGVPSGWSIAHKTGTGQHSGYNDVGVLTAPDGRQYALAVMIAR -TRTSYAARFEMMQSVTRAVVEY- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides fragilis TaxID=817 RepID=F7LMZ5_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLKTRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHENLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNEIGFILLPDGHAYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI000EFDC465 ---SLETQLKEAIKDKKAEIGIAVI-TDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKTDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sp. NS1 TaxID=2338327 RepID=UPI000EA99982 ---ALERTVAQIANGSGGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAIAATFMEGVE -KGRWTLSSEFPLMVPVASAFSSTKAPVVPGKYSAVDLIEMMITRSSNPATDALLKVVGGP -AAVNAWAARNGMPDFNITRDIATLVRAQRIDVRDSATPQTMGRLLAGLYQGKFLRESSRR -VILGAMERCRTGARRIKGMLPSGVQVAHKTGTLNN-TASDIGIMHTPDGRAIAVAIYVTG -QG-SKPARDAKIASIARALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000F0B5EC4 ------SAVRELAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILAGGTQN -FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCMEw ->[subseq from] Beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=A0A410E2S3_9BACT -------SAVQLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPQDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X7G9_9BACT ---ELSARLKDICERAGGRCGVAVTHVETGRGA-AFEGATPLPLYSVFKLPLAVAVLKEVE -EGRLQLDQKVRVEPEETVPGTEENSALWRQPRPLRELLEFSIARSDNTSTDKMLELVGGP -EAVTRRMRALGLDHIEVRSTVKEFLKS-RDAHPNTGAPEDLARLLVLLRKGEVLAPPQSA -LLLGIMARTVTGDRRLRAGVPAGTPVADKTGSGPS-TTNDVGVVTLPDRGHLALAVLLDG -SKLPSKQQEDLIAEVARAAYEA- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A523WX73_9BACT --eRLKKQIEGVIRGTEGEVGVAVKHLESGQEL-YINGDMNFPMASVFKVPILVEVLAQIK -EGKFTLKDEISIQKTDQHLGSGMLSDLEAPGLSLRNLITMMMIISDNSATDILLTKV-GA -ENVNNRLRSYGIGKITVNRTCQHLIMKFSQIMKDQSTPRAMNRLLEMIYKKDVLNEESCD -LILSVMLECQTGKGRIKGDLPGRTKVAHKTGTIG-GTVNDSGIIYLPDNGQVALTIFTKD -MTLKGKDVDQIIAQIAKFVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium estronivorans TaxID=1577690 RepID=UPI00123A0172 ----LMGEFARFATLTDGTVGIAVRDLSSGETL-AYNGDTLFPMASTYKVAVAAKIFSLLD -AGSLNLDEKLT---------------RLGRPLPVRTLLEMSLTQSDNEATDALVARTGGP -QAVNDWVRSIGVKNLRVDSNTRDLLAGFAMDPRDTATPRAMDDLLVAIRSGKALKPQSTA -MLLSIMERCKTGKDRLRAMLPPGTRIAHKTGTLN-GIGNDVGIVTLPDGRLFAITVFVMK -DYKGHQMRDRIMAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter aquimixticola TaxID=1958945 RepID=A0A419RRF2_9SPHN --dALAAEIDRLALDFGGSVGLAVVDVQTGWHT-GYEADQLFPQQSVSKTWVTLTALDQID -KGELDLARKVTLTRDDLAVYQPIRKEILRSGTDVADLIERAITQSDNTANDALLNIVGGP -DAVRQTIVDKGLGQIRFGPGERAMQSRYLSNPVDGATPLAIARALAKLTRGELLSETATA -YFLTTLERTKSGPRRIKAGAPDGWRVAHKTGTGQQSGYNDVGLITAPDGSSYAIAVMIGE -TRKPTPERMALMQAATRAVAEY- ->[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. DHC06 TaxID=1770545 RepID=UPI00102EB829 ---RLQQALDAAVQGSPGTLGVAVLDLRTGATV-GVHADQPFPMMSVFKAPVAAAVLARIE -AGSLSLSQEVTASRDDLQEGSAVPGKEVKAGFTIERLLKGAVSESDNTAVDILLRVMGGP -QAVMAFLHAHGIDGMRVDVDEAGVSRAFLADPRNRSTPAGAVEFLRKLQGGELLSPTSTQ -YLLRLMAAQTK-PNRLRVGVPQGVQFADKAGTSATAAYNDIGIMSWPDGRIVIIAAFLSD -STASGKERDALFADLARSVA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1Q3T6_KLEPN ------------------------------------------------KGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTAND-------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides fragilis TaxID=817 RepID=Q64WX6_BACFR ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQGRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD -SEADNRENSEIIAEISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. P6W TaxID=1609758 RepID=A0A2Z5E754_9SPHN ------QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWSLTSEFPLMVPVGSASSAVAPVRAGEYMSALRLMELMITRSNNYATDALLKVVGGP -KAVNAWVERAGIDDWHIDRDIATLVRARVVDTRDSATPYAMVQLLSGIYQGKWLSPSSRS -ALLGAMSRCVTGKRRIPAGLPEGAQVSHKTGSLNN-TSSDVGIVQTPDGRVFAIAIYVTG -QG-GRPGRESRIASIARTVYNGy ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. CA7 TaxID=2604424 RepID=UPI00129532FD ---TLTQKIENIISGKKADVGVSVIGVQKNDKV-QINGEKFYPMLSTFKFPIALTTLHQVE -KGKLRLDQKMLIKKEQLLEWSPFREKYPEGNITLEDALQWMMCYSDNNLTDIILRLIGGT -EPVQKLIGS----DFIIKNDEEGMHKDWDSQFINTITPNKAANLLEKFYQGKILNKARTQ -WLYNAMLNNQTGLKRLKGKLPANVKVAHRSGTSFTGAVNSYGIIELPHNKKIVVAVFVHN -TYESFDNAEAIIADISKAAYDHy ->[subseq from] Beta-lactamase n=1 Tax=Paraprevotella clara YIT 11840 TaxID=762968 RepID=G5SR83_9BACT ---DLQEQLRRMVADKKAQVGIAVI-VDGSDTL-TVNNDVRYPMMSVFKFHQALAVADACG -RRGVSFDTLVYIRPDDLRPYSPLRDKYPEGNLSVGELLKYTLHLSDNNACDILFRVFGGP -AATDEYLRSMGLRDFAIEATEDDMHRNLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD -FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGRRYSIAVLVRD -SEESEQATARIIADVSEAVYRY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A5M6AKV4_9BACE ---SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Pedobacter miscanthi TaxID=2259170 RepID=UPI001314E112 --kKLEVTVAEIAADTRGKIGIYARVLESNETF-EFNNNQHFVMQSVFKFPIAVMLLSEVD -KGKFNLDQQVFIPKSKIKKTSKLYEKYPEGNVPLREILEDMVLYSDNNACDVILQLLKGP -RALTRYLHGIGITDINVDFDEWGMQKKWNNQYQNWCTPQAQVTLLKLVFEQKLLKSETNT -LLRTLMRKTYVAPMRIRGLLPKGTLVEHRTGTSATNATNDVGTITLANGKHLAIAIFLMD -SYENNEKRDLIIAKIAKAAVDEf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A4R1W8M1_9SPHN ----FGKQLAAVAEASQGRIGVAAMDLSSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWTLSSEFPLMVPVPSASSAVAPVRAGTYMSARQLIELMITRSNNYATDALLKVVGGP -SAVNAWVRRTGIDDWHIDRDIATLVRAKVVDKRDSATPIAVVQLLSGIYQGKWMSQQGRD -VLLGAMSRCVTGKRRIRAGLPAEVSVSHKTGSLNN-TSSDIGIIETADGHAYAVAIYVTG -QG-TRPNREARIASIARTIYNGy ->[subseq from] class A beta-lactamase n=2 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0011782736 ------SAVQELAHSLKARVGMAAEMLDTGETV-AVGDEAAYPMQSVVKFVLALSVLKRVD -QGVMNLEQIIRIRPEQLVKWSPLRERSPQGGFSLKELLKVTVQESDNNTCDLLFSLIGGP -QAVQKDLTEWGIDGINVRFTEDEIHRNRDLQYANSSRPSAMNSLLRAFDEGKILKKGTQH -VLWDIMAGCSTGHERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSMFIRD -SKDSESACDRMIASMARWLCMEw ->[subseq from] Beta-lactamase n=2 Tax=Erythrobacteraceae TaxID=335929 RepID=A0A0P7W274_9SPHN ---SFEQRIAELADGSQGRIGVAAVDLATGEEI-AVLGDQLFPMASTSKIAVAATYLDMVE -KGQFSLTSEWPLKIPIRSAFSTVAAPVREGSMQAIELIELMITRSSNPATDALLAAIGGP -AKVTEWVHRQGIEEFSIDRDIATLVRANWIDPRDAATPRAMVRLLQGLYRGDFLSDTHRK -VLLGAMSRTVTGQRRIVANMPEGASVSHKTGSLNN-TSSDIGIIEYPDGRAIAVAIYVTG -QG-TRLARERRIAAIARALYDGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CAG8_ECOLX -------------------------------------------MWQTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDRTG----------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Thermosynechococcus vulcanus TaxID=32053 RepID=UPI000F8D3BB9 ---NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD -EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA -AELNQQFQEWGLENTVINNPLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMVYQAf ->[subseq from] serine hydrolase n=1 Tax=Erythromicrobium ramosum TaxID=35811 RepID=UPI001324815B ---NWQQRIAELADPAQGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATFLEMVE -KGRYTLTSEFPLMMPVASAYSSTKAPVRAGQMPAIDLIEIMITRSSNPATDALLAAVGGP -AVVNDWIRRQGITNFSINRDIATLVRAVHIDTRDAATPRAMVRLLSGLYRGDFLSDQSRQ -VLLAAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIECPDGRTIAVAIYVTG -QG-TKQAREERIAAIARALYDGf ->[subseq from] Tll2115 protein n=2 Tax=Thermosynechococcus elongatus TaxID=146786 RepID=Q8DH45_THEEB ---NLQQQIQQLVSRQNLTAGLYFFNLDSGASL-NVGGDQVFPAASTIKFPILVAFFKAVD -EGRVTLQERLTMRPDLIAPEAGTLQQKPNSQYAALEVAELMITISDNTATNMIIDRLGGA -AELNQQFQEWGLENTVINNPLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMVYQAf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=A0A1B8ZSH7_9FLAO ---DLTQQLTTLIAGKKADVGVSIIAPYKREII-QINGNRLYPMLSTVKFPIALTILHKVE -KGELSLQQKLFIKKEELLEWSPFKKEYPEGNISLEDAIKWMVSYSDNNLTDILLRLIGGP -EPVQKFINS---KNFIIKNNEEDMHKDWQSQFINTITPNEATRLLEKFYNGKFLNKKHTQ -WLYMAMINNASGAKRIKGNLPKTVKVAHRTGTSFTGAVNDFGIIELSDKERIYIAVFVHD -TYETFENAEAIIADIAKATYDYy ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. G0186 TaxID=2487064 RepID=A0A3G6PPQ8_9FLAO ---ELKKLIEAIISGKKADVGVSIIGLSKKEVT-QINGNKFYPMLSTVKFPIALTILHQVE -KGELSLHQKIYIKKEELLEWSPFKKEYPDGNLTLEEAMKWMVSYSDNNLTDILLRLIGGP -ESVQKFITS---KSFIIKNDEEGMHKDWDSQFINTITPNEATRLLEQFYNGKILNKEHTK -WLYTAMLNNVSGAKRLKAHLPKGVKIAHRTGTSFTGAVNDFGIIELSDKKRFYIAVFVHD -SYEKFEDTEAIIADIAKAATTHy ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3A0DRR8_9BACT --dELADKIQPLVDAHRGRVAVAIKDLKTGASF-EHNATEAMPTASLIKFPLMIAAYQAVE -EGRLTLDDKLTLAESDKVPGSGILTPHFSAGISLRDAIELMIVYSDNTATNLVAEKV-GL -AATAELMEKLGCPETKMNAKVFRRDTRSKQYGLGSTTAADMVKLLEQLSDKKLVSGAASE -KMLAHLYACED-KQKFPRYLP-GVKIAHKTGSVNE-VRTDAGLIDAPSG-PIAICVLTNE -NQGDRNEAEILCGKIAQIAYRHf ->[subseq from] Beta-lactamase n=2 Tax=Dyella sp. 4G-K06 TaxID=1927958 RepID=A0A370WYV7_9GAMM ---RLQRALTRLAAEAPGMLGVTVLDLDAGTAV-RVNADRAYPMMSVFKPSVAATVLAKID -AESISLDQTVTVARKDVEDGAPSIGAHFTGEFTVRRLLAAAISESDNTAADALVRLVGGP -RVVTAFLRAHGIDGMRVDLDEAGVSRAYLNDPRNRTTPDAAADFLKKLWQGRLLSPGSTR -RLLDLMYGQTI-PARLRNGLPPGVRFADKCGTSYTAAYNDIGIITWPDGHTVIVAAFLTA -SHADKKHRDALFAQIAREVS--- ->[subseq from] Beta-lactamase n=2 Tax=Moorea TaxID=1155738 RepID=A0A1D8U312_9CYAN -----------LVKDKVGTAGVAARPVEGGCLI-LLNAKKWFPMASTVKLPIAMALLDQVD -AGNLRLDTLVEIDDSEWVLSPVVASEFVHPGLSVANLIEVMITLSDNTTTDVCLRLVGGP -DAVDDYVTSLGIKGMDISRYMRGLLKAFEADPRDQVKPLAMLDLLLKLFNGDALSPDSTQ -FLLGIMGRTKTGSGRLKGLLPSGILVEHKTGTVG-GVANDVGYIRLPDGRRVAIAVFTKS -STKAPQERERAIAEIGRLLFDVy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. TaxID=1871047 RepID=A0A349ZX58_9FLAO -------EIVEIMTGKKATVAVSVLDFQDCTSY-HLNAGNSMPMLSVFKFHIALAALDQVD -KGTLQLKQEFLIKKEDLKEYSPVRKLYPDGNLTLEKILYYMVAESDNNLTDYLLNLLGGP -DYVHQYIKNKGVRDTYIRADEDVMHKGFKYMYLNTTTSKAATDLLQKFYKGNILSKASTE -TLLNIMFATSTGANKLKALLPVGTQIAHKTGSSGKDAENDIGIIVLPSGKVYAIAVFIKD -SKESEEINTKMIAAISSAVNQYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A412FXN8_9BACE ---SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A174I1I3_9BACE ---SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F1DI14_ECOLX ------EQIKQSESQLSGRVGMIEMDLASGRTQtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGSTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAAT---------------- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium arthrosphaerae TaxID=651561 RepID=UPI000F4F644D ---DLTQQLTTLIAGKKADVGVSIIAPYKREII-QINGNRLYPMLSTVKFPIALTILHKVE -KGELSLQQKLFIKKEELLEWSPFKKEYPEGNISLEDAIKWMVSYSDNNLTDILLRLIGGP -EPVQKFINS---KNFIIKNNEEDMHKDWQSQFINTITPNEATRLLEKFYNGKFLNKKHTQ -WLYMAMINNASGAKRIKGNLPKTVKVAHRTGTSFTGAVNDFGIIELSDKERIYIAVFVHD -TYETFESAEAIIADIAKATYDYy ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5268 TaxID=2019662 RepID=A0A2N6KAS6_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIGSISKATYQQf ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A1G6G538_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -NAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] ClassA n=3 Tax=Bacteria TaxID=2 RepID=A0A127SGP2_9BACT ---QFESRLDEILSGHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ -REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLRGTTTGANKLKAGLPASTVIGHKTGSSDRTADNDVGYVVLPDGRRYCIAVFVTE -SEENDATNAAIAASASRAAYEYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CA69_ECOLX -------------------------------------------------VMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGAGG-------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium abikonense TaxID=86193 RepID=UPI000789471A ---KLLGEFERFATLSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID -AGDVRLDDQLALDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP -AAITQFVRGLGVDGLRVDSDTAHLLYAFAAEIEDTSTPRAMLDLLTAYESGKALSAGSMQ -RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK -DSKGHKSRDRIIAEAARAAYDYf ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=2 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A395VYM2_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIANISRIVYEY- ->[subseq from] Beta-lactamase n=2 Tax=Staphylococcus cohnii TaxID=29382 RepID=A0A658S140_STACC ------KSFDQIEQDNDTIIGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNRP ---TSELNKKIAISKGDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KEFQQSLIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE -LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] Beta-lactamase n=1 Tax=Paraprevotella clara CAG:116 TaxID=1263095 RepID=R5NKQ1_9BACT ---DLQEQLRRMVADKKAQVGIAVI-VDGRDTL-TVNNDVRYPMMSVFKFHQALAVADACG -RRGVSFDTLVYIRPDDLRPYSPLRDKYPEGNLSVGELLKYTLHLSDNNACDILFRVFGGP -AATDEYLRSMGLRDFAIEATEDDMHRDLADCYRNWTTPLEAVRLLEWLVSGKAAKGAYRD -FIEQTMISCQTGRDRLPAPLATKAVIGHKTGTGDRNGTNDIGFVFLPDGRRYSIAVLVRD -SEESEQATARIIADVSEAVYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5C9H1_ECOLX ---------------------------------------------------AAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGFG------------------------ ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A4V1YZE1_9BACE ---SLETQLKEAIKDKKAEIGIAVI-INEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLKIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI0011065365 ---SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALANYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=Q45118_BACFG ----LETQLKKAIEGKKAEIGIAVI-IDGQDTI-TVNNDIHYPMMSVFKFHQALALADYMH -HQKQPLETRLLIKKSDLKPYSPLRETYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DAVNKYLHSLGIRECAVIHTENDMHKNLEFCYQNWTTPLAAAKLLEIFRNENLFDKEYKN -FIYQTMVECQTGQDRLIALLDKKVTMGHKTGTGDRNGCNDIGFILLPDGHVYSIAVFVKD -SEADNRENSEIIAEISHIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Legionella wadsworthii TaxID=28088 RepID=A0A378M285_9GAMM ---ELLKKIKEIERKSNTIIGISAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLDRMIKMDSRNSVPGSGGLHYLFEKKISLKQILMHTLKNSDNSASDALLKAVNGP -RYVAKRMKDLGLQNISINRSIMEMFIRFQKDVRDTTTPNDMAKLLVKLYKKQALSEASTN -LLMKIMEQCRTGRSRIRGLLPGNVKVAHKTGTWSYRFVSDVGIITLPNKGHIALAVYVKS -KSASDYSRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=V5W480_ECOLX ------------------------------------------------------------- --------------------------------MVLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAA------- ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. ANK073 TaxID=1766800 RepID=UPI0013596D74 ----------------------------DRRAF-RYRAADLFPMCSLFKPLAAAALVRARG -YDDAYWSTPIPFTDADVVRDSIVLSTLRPRQATPEQLADAAIRFSDNTAGNLLLRELGGP -AAITAFATELGATHTRLDRWEPDLNEARPGDVRDTTTPDDIAALYSALLLEDAAGVLASS -RLREWMLRTTTSGARMRAGLTAPYELADKTGGGEYGVVNDAGVLWRPGLEPTTLVILTRT -DRFDAVRNNEVVAEATRIVV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinokineospora auranticolor TaxID=155976 RepID=A0A2S6GT05_9PSEU -------------------------------------------------------MLRRAE -ADPGYLDKLVRYDRSRLEEYAPVTGERVDTGMTVAELCAASVGVSDNTAANLLFDEVGGP -AGATAFVRSLGDDITRMDRNETSLNVGAPGDERDTTTPRRIVETYRALLLGTALAPTGRD -RLTGWLVGSTTGKDLVRAGLPADWRAGDKSGSGAAGEVNNVAIAWPPGRGPWLIGVYTAP -TKA-EPPARPIVAEAARIVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Dyella sp. 4M-K27 TaxID=1927959 RepID=A0A3S0R3H3_9GAMM --kQLQHALLNLAQRAPGLLGITVLDLDTGVQV-RINADRAYPMMSVFKAPAAAAVLALVD -AGKLSLDQTVTLTRADVVDGSPSIGAHFRGDFTLAQLLTAAVSESDNTAADALVRLAGGP -RAVTGYLLAHGIDGLHVDLDEAGIDRAYLSDSRNRTTPDAAADFLNKLWKGQLLSPSSTR -RLLQLMYAQTT-PSRLRAGLPEGVRLADKCGTSATAAYNDIGIMTWPDGHTVIVAAFLTA -SHMDRAGRDAVYVDIAQSIVQ-- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. Y-01 TaxID=2048898 RepID=A0A3G8VIH9_9MICO -----------------------AVDTGTGESV-SYGEDRRFGFASTIKAFAAAVFLQSVP ---GAARDEMVHWTAEEAAAHAPVTSQHVEDGLTYAQLAEAAVRVSDNAALNLIVDRIGGS -AALDDALAELGDATTEVVNDEPTLNTIEPGSTDDTTTAAAFTASLTRILDGSTLSAADAA -LLVDWMSDNRTGDALIRSGAPAGWTVADKSGGAGP-IRNDIAVVTRPGQDPIIITVLTSR -NDPHADFDDTLVASAASITL--- ->[subseq from] Class A beta-lactamase n=1 Tax=Pedobacter miscanthi TaxID=2259170 RepID=A0A366KW83_9SPHI --kKLEVTVAEIAADTRGKIGIYARVLESNETF-EFNNNQHFVMQSVFKFPIAVMLLSEVD -KGKFNLDQQVFIPKSKIKKTSKLYEKYPEGNVPLREILEDMVLYSDNNACDVILQLLKGP -RALTRYLHGIGITDINVDFDEWGMQKKWNNQYQNWCTPQAQVTLLKLVFEQKLLKSETNT -LLRTLMRKTYVAPMRIRGLLPKGTLVEHRTGTSATNATNDVGTITLANGKHLAIAIFLMD -SYENNEKRDLIIAKIAKAAVDEf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D19D12E ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHKSGERFAFASTYKAISSGILLQNRP ---TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIGGI -KEFQQALIHRGDHISNPQRPEPDLNLYDPQSTDDTTTPKRAATTFNHLLHSENMSKANLE -LLKHTMIHNETGDTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter soli TaxID=1739690 RepID=UPI00136AA72B --kALHEEIRALGKSFDGEIGLAVRDVASGWTA-HYEGNDRFPQQSVSKLWVAIAAMTLVD -RGKLDLKQEVTLTREDLTLHQPLRALALRPQTTLEDLLVKAITRSDNTANDYLLRRVGGP -NAVRTVLAELGIAGVRFGPGERIMQSAYIADPVDGATPIGMVDALARLQKGQLLSPASTA -QLLGILEQTRSGAQRLKGGLPPGWTIGHKTGTGQQAGYNDVGILTAPSGRTYAVAVLMGR -ASQPQPVRRALMHALVRVIAEY- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A519WG84_9SPHI ----VSKKVDSIVTSKRAIVGFSVYILETGDTL-SLNGSRHFPMQSVYKFHLALVVLEMVD -RGKLSLGQKVLLKKADLPPHSPLRDKYPNGNVSVDELLRYTVGQSDNNGCDILFKLVGGP -KVVDQYMKKIGIKDVAVVGTEAQMHADYMMQFKNYSSPKASTNLLLKFFQGKILKAGTTE -YLMKIMQESASGPNKLKGLLPAGTLVAHKTGYSGY-ATNDIGIVTLPNGNHMLISAFVMM -SKETEAVNDRLIAELAKLAFDKy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter aquimixticola TaxID=1958945 RepID=A0A419RVD0_9SPHN ---AVQQRISQLAEGSQGRIGVAAIDLTTGESI-SILGDQRFPMASTSKIAIAATFLEGVD -QGRWSLTSEFPLLWAVRSRFSSAAAPVRQGEMTAHRLIDLMITRSSNPATDALLAAVGGP -QAVNDWARRAGLEDFSLDRDIATLVRVTYIDRRDSATPNTMVQMLAGIYQGRWLSGTSRN -VIISAMERCRTGTRRIPAQMPSYVNVAHKTGTLNR-TASDIGIIEMPDGRAIAMAIYVTG -QSANRLRRDARIASIARGIYD-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides sp. D22 TaxID=585544 RepID=D7J8T3_9BACE --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDIFFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A413EP36_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -NAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A413V1G0_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. (strain 113P3) TaxID=292913 RepID=A0A0M4D6J6_SPHS1 ----LEQRIFELWRSFPGKTGIAVQRIDGEWTL-QQRGDELFPQQSVSKLWVALTVLDAVD -RGALTLDRKVTITPADLTLHQPIAARVRAEGMSVRELIETAITHSDNTANDSLLRTVGGP -DAVRRFIAAKDLGAIRFGPGERLLQSNYLANPVDGASPSAIARALTRLARGTLLSPESTD -YILGVMSRTRSGPNRLKAGLPSGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS -TTASIPQRMVLMQAVSGAVAE-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium J003 TaxID=2420340 RepID=A0A3M2FRK1_9CYAN ---SLQQQIQQLVTRQNLTAGLYFFNLDSGASL-NVGGDEVFPAASTIKFPILVAFFKAVD -EGRVRLHERLTMRPDLIAPEAGTLQQKPNSQYSALEVAELMITISDNTATNMIIDRLEGT -AALNQQFQEWGLENTVIHNLLPDMKGT------NTTSPRDLATLMLKIGQGEILSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMVYQAf ->[subseq from] serine hydrolase n=1 Tax=Sphingobium bisphenolivorans TaxID=1335760 RepID=UPI0003A09FEF ---RLMNEFSRFAALTDGTVGIAVRDLSSGEML-SFNGDTLFPMASTYKVAVAGKILALLD -HGQLGLDEQLP---------------RLGRSMPVRALLDMMLTQSDNEATDALVARAGGP -AAVDGWVRALGIKGLRVDSNTAQLLAAFATDPRDTSTPRAMGELLSAIRQGKALKPSSTA -LMLSIMDRCKTGKMRLRAMLPPGTQIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHRGHVIRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix sp. PCC 7601 TaxID=1188 RepID=A0A0D6L2M5_9CYAN ---SLKSAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-ARAEKLISGISRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Fluoribacter dumoffii TaxID=463 RepID=A0A377GE13_9GAMM ---ELLKKLNAIEKKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDSRYSVPGSGSLHYLFEKRITLKEILKHTLRNSDNSASDALLQAAKGP -KYVAQRMSALGFKNIFVNRSIMEMFVRFEKDIRDTTTPNDMAKLLVKLYKKQALSESSTN -LLMDIMEKCRTGRSRIRGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2D8TBN4_9SPHN ---KLLAEFERFAALSDGTVGIAVRDLQTGETQ-SFNGDTLFPMASAYKVGVAGRIFALVD -AGDLRLDDQLALDPALASEGIAWMFSRPGAALSVQRLLELMLQKSDNNATDVLVARAGGP -QAITRFVTGLGVNGLRVDSDTAHLLYSFATEIEDTSTPRAMLDLLSAYESGRALSADSTQ -RLFTIMAHCETGKHRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK -DGKGHKARDRIIAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Legionella quateirensis TaxID=45072 RepID=A0A378KSP4_9GAMM ---ELTKKISAIEKKSNSIMGITAIYIEKNKVI-THNSTQRFFMASTIKLPIAMAFLHRVD -QKKDSLNRIIKLGLSNSVPGSGTLHHACEKKMSMQQILKYMLTNSDNSASDTILHTVNGP -EYVTKRMYELGFKNIFINRSILEMFMRFENDKRDTTTPDEMAKLLVKLYKKEALSESSTQ -VLINIMEQCRTGRSRIRGLLPGNVKVAHKTGTWAPGFASDVGIITLPNNGHIAIAVYVKS -QAASDYSRSRAIALASRAIYDHf ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1K7B0_9ZZZZ ------------------------------------------------------------- -----------------------VTEKHLTDGMTVRELCSAAITMSDNTAVNLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIA---------- ->[subseq from] Serine hydrolase n=2 Tax=Bacteria TaxID=2 RepID=A0A515LB61_9SPHN ----IEAMVARIADGSNGRIGVYAVDLASGRQV-SVLGDQRFPMASTSKIAIAATFMEGVE -RGRFSLTSEFPLMVPVASAFSSSKAPVVPGKYKAVDLIEMMITRSSNPATDALLAAVGGP -AAVNSWAQRNGIGEFNLTRDIATLVRARSVDVRDSATPQAMVSLLTGLYQGKFLTDRSRQ -VILGAMSRCKTGTRRIPAMLPSGAQVAHKTGSLNN-TSSDIGIINTPDGRAIAVAIYVTG -QG-SRPAREAKIANIARALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium timonianum TaxID=1805473 RepID=UPI00083B78D9 ----FKKIIETILAHKKADVGVSILTAGTKKEVtQINGNKPLPMLSTFKFPVALAVLHKVE -KGELSLQQKIYIKKEELLEYSPFKDKYPEGNLSLEDCLQWMVVYSDNNLTDILLRLIGGP -DDVQNFINS---KDIVIKNDEEGMHKDWDSQFINTITPNEAIRLLERFYTGKILNKEHTK -WLYTAMLNNATGIKRLKGKLPKDVKVAHRTGTSFTGAINDYGIIELSDKKRIYIAVFVHD -TYETFENSEAIIADIAKAAYDYy ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. HKB08 TaxID=2502843 RepID=UPI001008E662 ----FEKRIAMLADGDKGRIGVAAVDLATGEEI-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWSLSSEFPLLIPVRSAYSSDRAPVRRGKLPAEELIELMITRSSNPATDALLDVVGGP -SAVNDWMRRNGIGEFQLTRDIATLVRATFIDKRDSATPKAMVELLTGLYQGKFLSASSRR -VILGAMERCVTGKRRIPALLPASANVAHKTGSLNN-TSSDIGIIQSPDGRAIAVAIYVTG -QG-TRLNREARIAEIASALYDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9JQX3_9BACT ---RLEREMARLAQGAGGAVGVAVTHLETGRKV-ALRGRERFPMASSYKVPIAVRLLERVD -RGELRLDQMVELRAKDLHPGSGTLTDLFNKPLSVRNLLELMLLISDNSATDVCLRLAGGP -ERVMARMREVGIQGIDVNRSTAQLIARFNADRRDTAEPEAMRALLERIWARDLLRPDSAE -LLLDIMRRCRTGGARLRGILPAGTEVAHKTGTIG-GTTNDVGIVTLPDG----------- ------------------------ ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A5M5NE31_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. D2 TaxID=556259 RepID=E5C4M8_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMA0_9BACT --sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDPFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=Streptococcus mitis TaxID=28037 RepID=A0A0K2D1V6_STRMT --sELENRIGSLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYFAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. KY5 TaxID=2011159 RepID=A0A2Z4JW68_9SPHN ---SFEQRIAELADGGRGRIGVAALDLATGESV-SVLGDQLFPMASTSKIAVAAAYLEMVE -QNKYSLTSEFPLLIPIRSASSPAAPVRKGNYMPAIDLIEIMITRSSNPATDALLAAVGGP -EKVNDWMRRQGITDFSIDRDIATLVRANWIDPRDAATPSAMVRLLQGLYRGDFLSDQSRQ -VLLGAMSRTVTGRRRIPANMPDEAVVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG -QG-TRLNREARIASIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Legionella sp. km535 TaxID=2498107 RepID=A0A433K700_9GAMM ---EIAKKIAAIEKKSNSIMGITAIYIEKNKVI-SHNSTKRFFMASTIKLPIAMAFLHRVD -QKKDSLNRIVKLGLSNAVPGSGALHHACERKMSMQQILKYMLANSDNSASDTILHTVNGP -EYVTKRMYELGFKNILINRSILEMFMRFENDKRDTTTPDEMAKLLVKLYKKEALSESSTQ -ILIKIMEQCRTGRSRIKGLLPGNVKVAHKTGTWAPGFASDVGIITLPNNGHIAIAVYVKS -QAASDYSRSRAIAQASRAIYDHf ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter cryptus TaxID=196588 RepID=UPI0004092F6F ---SLQQRIAELANPALGRIGVAAVDLSTGEEV-MVLGDQLFPMASTSKIAVAAAFLEQVE -RGRYSLTSEFPLLLPVASPSSAKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP -AVVTDWMRRHGINEFSINRDIATLVRATTIDPRDAATPRAMVRLLAGLYRGEFLSAESRA -VILGAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG -QG-SKAAREERIAAIARALYDGf ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Fremyella diplosiphon NIES-3275 TaxID=1973485 RepID=A0A1Z4MG52_MICDP ---SLKSAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-ARAEKLISGISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5201 TaxID=2019672 RepID=A0A2N6N240_9CYAN ---SLKTNLQSLTSANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMMVGGSGDMQKPVGTQFKALEVATKMMTVSDNTATNMLIARMGGI -EALNQRFRSWGLNTTAIRNQLPDLQGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILDIMRNTVR-NHLLPTGLGQGASIAHKTGDIGT-MLADAGLVDLPTGKRYIVTVMVQR -PNND-PRAEKLIGSISKATYQQf ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A494JAI3_9FLAO ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMFPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFMDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium nitrogenifigens DSM 19370 TaxID=983920 RepID=F1Z6N3_9SPHN ---AIQRTVEAIVARARGRVGVAAVDLDGGGQV-LVNGDMPFPMASTAKVAVAATFLAGVE -QGRHRLDQQLPMMMPVAERHSAVAAVRPGPVMTAQQLMELMITRSNNHATDGLIAAVGGI -GAVNSWLSKNGIVGQHLDSTMATLVRAKTIDTHTSSTPRAMAALLAAIDRGGALSPQSRA -VLLDTMTRTSTGKNRMRAGLPEGTIFAHKTGTLS-GVTDDVGIIRLPDGRHLALAVFVAG -PEGH-LIHANMIAQITRALYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Asaia astilbis TaxID=610244 RepID=UPI0009FFD389 ----------RYERASGGRIGAHLFCPQTGLAI-SWRGEERFLMCSSFKASLAACVLKRCE -GDEDDLTRRLSFVDSDFKTWAPVARQNRDAGLSLAALCAGAVSMSDNVCANMLLRHIGGP -AALTKFWRDSGDDITRLDAYEPELNRPSADPEANTTSPIAMARTLHRLIHGTLLRPHSAA -LLRDWMTSCVTGTHRLRAGLPLTWAAGDKTGNNGKDISADIAFASPANSGSVIMAAYTAG -GKPDEARFRSVFHDLGAL----- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4V1SSA7_9SPHN ----LEATIARIADGSAGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAIAATFMEGVE -RGRFTLTSEFPLMVPVASAFSSSKAPVVPGKYKAVDLIEMMITRSNNQATDGLLAAVGGP -AAVNDWARRNGIAEYNLTRDIATLVRARTVDIRDSATPEAMVRLLSGLYQGKFLAESSRK -VILGAMSRCRTGTHRMRAMLPDEARVAHKTGTLSN-TASDVGIINTPDGRAIAVAIYVTG -QG-SRAARDAKIASIARALYDGy ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. Leaf26 TaxID=1735693 RepID=A0A0Q4ITK4_9SPHN ---KLLAEFTRFATLSDGTVGVAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD -AGEVRLDDQLALDPALASEGIAWMFNRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP -QAITAFVQKLGVTGLRVDSDTAHLLYAFAMEPQDTATPTAMLDLITAYESGRALSAASTQ -RLFTIMAHCETGKARIIGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAIVAFVMK -DSKGHVSRDRIIAEASRAAYDYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A3E5HQM2_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETQLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Parabacteroides timonensis TaxID=1871013 RepID=UPI00094EF2C4 --eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TINNEDPYPMMSVFKFHQALAVLNYLQ -QNNLPLDTPIRIEKEDIIEYSPLRDKYPQGNLPISELLKYIIQLSDNIACDVLFKYIGGP -SVADKYIRSLGIQQFSIVITEDDMHQDLSACYLNWSTPLEATRLLEILLTRPLFKDEYQE -FLKNIMIECETGKDRLPQLLKTDAVIGHKTGTSDKGGTNDIGFVLLPNGSRYTVAVFIKD -SNESMETNAKIIASISEVIYKYf ->[subseq from] Beta-lactamase class A n=2 Tax=Bosea sp. 124 TaxID=2135642 RepID=A0A2T4YEM7_9BRAD --aKLDREIVAIERQSKGRLGVALLDLKDSRTW-SHRGTESFPMQSVFKWPLAIAVLQAVE -AGRFKLDEKITIRRSEFSLHSPLAKAFEGESYPLRELIALAAGESDNTAADILMREIGGP -RVVRAMLAAGGIQGITVDRYERQFQPTALKDRRDSATPEASVLFVEAQARGNWLRGPAHN -ALIDIVTETKSGADRIRAGLPEGARFAHKTGLGLNHATNDIGLVNLPNGRVFAIAVYLAG -STADARTREAAHAAVAKLAVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI000C999D6E ------SAVRELAHSLKARVGMAAEMLDTEETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter jejuensis TaxID=795812 RepID=UPI00136F2C64 ---SFERRIAQLADGSKGRIGVAAVDLSSGEQI-SILGNQRFPMASTSKIAVAATFLEGVE -QGRWSLTSEFPLMIPIRSKYSSRAAPVRKGNMPAIDLIEIMITRSSNPATDALLKVVGGP -NAVNGWARRNGIREFSIDRDIATLVRVSYIDRRDSATPRAMVDLLAGLYQGKFLSRESRR -VLMGAMSRTRTGKRRIPAMIPGEAEVLHKTGSLNN-TSSDIGIIRTPDGRAFAVAIYVTG -QG-TRRNREAKIASIARALYDGy ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YPY6_9BACL ---SLEQKLLDVISDVSGTFGVAVKHLQTGEAA-SINGDQLFQLASTFKIPILAALYRDVE -AGKLSLEDRIKITEEDMVPGSGVLQEHLGVEVTVKDLAMLMIIVSDNLATDQLLKLV-GT -DQVTAYMRELGLADVHIHHSCWDLLSVFQADPRNVGTPVDMAKLVELIALKELISEQACD -GMLDILFRQQF-NSRLPYMLPGKAKVAHKTGTLSS-VVNDVGVVYLPDNGAFSIAVLSKD -NP-SMEEGERTIGRIARAAYDHf ->[subseq from] Beta-lactamase n=2 Tax=Legionella moravica TaxID=39962 RepID=A0A378JTF7_9GAMM ---EIAKKIAAIEKKSNSIMGITAIYIEKNKVV-SHNSTKRFFMASTIKLPIAMAFLHRVD -QKKDSLNRIVKLGLSNAVPGSGALHHACERKMSMQQILKYMLANSDNSASDTILHTVNGP -EYVTKRMYELGFKNILINRSILEMFMRFENDKRDTTTPDEMAKLLVKLYKKEALSESSTQ -ILINIMEQCRTGRSRIKGLLPGNVKVAHKTGTWAPGFASDVGIITLPNNGHIAIAVYVKS -QAASDYSRSRAIAQASRAIYDHf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Pararcticibacter amylolyticus TaxID=2173175 RepID=A0A2U2PIZ6_9SPHI --tDLKQRVEQIISTKKADIGVSIQSSGTGETM-DIRGNQHYPMISIFKFHIALAVLNKVD -NKQLSLKQKIFVRKDELLEWSPFREKYPKGDITLEEALRWTVSHSDNNLGDLLIRLAGGV -RAISNFL---NDPSFIIKNNEEEMHKSWDAQFLNTTTPNFSTRLLDDFYNGKILSRKSTK -LLYEMLVETSVGLNRIKGKLPKETEVAHRTGSSFTGAINDIGIVKLPDGNYFIISVFVHN -TTERYKDGEEIIADIAKAAWDYy ->[subseq from] Penicillin binidng protein PbpA n=2 Tax=Thermosynechococcus sp. NK55a TaxID=1394889 RepID=V5V7C0_9CYAN ---SLQQQIQQLVTRQNLTAGLYFFNLDSGASL-NVGGDEVFPAASTIKFPILVAFFKAVD -EGRVRLHERLTMRPDLIAPEAGTLQQKPNSQYSALEVAELMITISDNTATNMIIDRLEGT -AALNQQFQEWGLENTVIHNLLPDMKGT------NTTSPRDLATLMLKVGQGEILSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDAGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMVYQAf ->[subseq from] class A beta-lactamase n=1 Tax=Moraxella sp. VT-16-12 TaxID=2014877 RepID=UPI000B7E2256 --nKLNEILPRWEKRLNAKIGMAIIN-DDGQIN-SYRKEDYFPVNSTIKAFIVAHVLFLVD -KGKLDLTQSILIKKSDLIEYSPVCQTFFNEKITISELCEATTTLSDNAAANILLNHLGGL -MAFNQFLKDIGADVV-LSHNEPLLNHAHYGETYNTAKPNSYAQSLKDIITKDILSNQSKN -QLLTWLINDKVADDLLRKHLPKNWRIGDKTGTGSE-SKNIVAVIWNAQNKPYFISLFITQ -PNDGKTQKSIAIANIGQ------ ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:754 TaxID=1262750 RepID=R6D3V4_9BACE ---SLETQLKEAIKDKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG -KRNQSLDTLLTVEKSDLKPYSPLRDKYPEGGMSIAELLKYTLQQSDNNACDILFHYQGGP -DSANKYIRSLGIQDCEITHTENDMHEDLDFCYSNWSTPLAAAKLLEIFRREPLFAKEYKD -FIYQTMVECQTGQDRLVALLDNGVIVGHKTGTGDRNGCNDIGFVVLPDGHTYSIAVFVKD -SEESSPENSKIIADVSHIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A650AIB5_ECOLX ------------------------------------------------------------- -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAFPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDI------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00124BDFD7 ------------ASRLGGTLGVVAHDLGTGERA-EVNAERRFTSASVIKIAIMATVLAEAE -AGRRSLDDRLPAPPDARVPGSGVIKDLADAAFSVRDLVTLMIIVSDNTATNLLIDLV-GR -DAVNAWCARHGLHGTVLARVMMDAAA-RERGEENLMTPADVAALLTGLVRGEMLGEASTA -FALDVLSRQQL-NDRLPRHLPPGVTLAHKTGELA-AVCHDAGIVLPKDRDPIVLVAMTEG -ID-SEPEAGTLIADTGRAVYT-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis granuli TaxID=267128 RepID=A0A0X8R5W0_9SPHN ----LDDRIASLWRAFPGKTGIAIQRIDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD -AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE -YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGN -TTASIPARMALMQAVSGAVAE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. HIX TaxID=1759074 RepID=A0A0W1EHE4_9SPHN ----LDDRLFQIWKAFPGKTGIAVQRIDGEWAL-TQRGGELFPQQSVSKLWVTLAVLDAVD -NGRLRLDQNVRIGPEDLTLHQPVAARVQSQGMTVRELIETAITQSDNTANDSLLRTVGGP -DAVRRFIDRKDLGAIRFGPGERLLQAAYRADPPDGASPAAIANALTRLARGTLLSPESTQ -YLLGVMTRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVLMGE -ASSPVPARMATMQSVSRAVAE-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00136F0D00 ------------ASRLGGTLGVVAHDLGTGERA-EVNAERRFTSASVIKIAIMATVLAEAE -AGRRSLDDRLPAPPDARVPGSGVIKDLADAAFSVRDLVTLMIIVSDNTATNLLIDLV-GR -DAVNAWCARHGLHGTVLARVMMDAAA-RERGEENLMTPADVAALLTGLVRGEMLGEASTA -FALDVLSRQQL-NDRLPRHLPPGVTLAHKTGELA-AVCHDAGIVLPKDRDPIVLVAMTEG -ID-SEPEAGTLIADTGRAVYT-- ->[subseq from] Beta-lactamase n=2 Tax=Akkermansia TaxID=239934 RepID=A0A139TSY4_9BACT ------ASIREIVRPLKAHVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD -QGVLDLDQKVQVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP -KAVQKDLKKWGVENMNVKYTEADTHRNNEWQYSNSARPSAMTSLFRRFDEGKILKKDTQL -FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN -SKDSPAVCEGTIASVARWLCTEw ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A5M6BIX5_9BACE ---SLEAQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1Z4N775_9CYAN ---SLKTAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-ARAEKLISGISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis italica TaxID=1129133 RepID=UPI00143A0A18 ----LNDRIYDLWRTFPGKTGIAVQRIDGEWKL-SQRGDELFPQQSVSKLWVALTVLDAID -QGRLTFDQRVRIGPEDLTLYQPLAARVRAEGMSVRDLIETAITKSDNTANDSLLRTVGGP -DAVRAFFDKKDLGAIRFGPGERLLQAAYLANPPDGASPEAIASALTRLARGTLLSPDSTE -YLLDVMSRTRSGPRRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGD -TNASVPARMELMQAVSGAVADY- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1I7H6_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATR---------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SP34_9BACT --sELENRIDSLRNGRKAPVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Culturomica massiliensis TaxID=1841857 RepID=UPI0008398E62 ---TLQKQIRSILKDKKAMIGVAVLY-NGKITV-SVNDDQGYAMLSTFKFPLALAVCDYLD -RQKLPLETEIYVSKADLHPYSPLRDKQPEGDISIKELLRYCVSLSDNNACDILIRYIGGI -ERLQQYIADLGFPDMVIVATETQMHQQTGNQALNRTRPSAAVLLFEQFLQKKLLSATYQD -FLEQILIETTTGANKLKGLLPSGTLVGHKTGSSDRNGDNDMGFVYLPNGNYFVIAVFIMD -SMEDDDTNASIIARISRTVYDHy ->[subseq from] Beta-lactamase n=1 Tax=Moraxella osloensis TaxID=34062 RepID=A0A2D2LXA5_9GAMM --------LPSWENKLNAKIGMAVITASNNELA-SYRGNDFFPFNSTIKAFIGAYILHLVD -KGQLDLAHTLQIKATDLLEYAPQSKKFFEANISIAELSEAMITVSDNTASNLLLDTTGGL -KPFNDFLHQIGNSEVILAHNEPLLNRSHYGEKIDTAKPIAYTQALKNILMGNILSEQSKK -LLLTWLINDKVGDSLLRKHLPNDWQIGDKTGAGDE-SRNIVAIIWNSQKEAYFVSLFITQ -PYKSNNQKSVAIAEIGRAIYS-- ->[subseq from] class A beta-lactamase n=1 Tax=Akkermansia muciniphila TaxID=239935 RepID=UPI0009E0AE99 ----------QLAHSLKARVGMAAEMLDTGETV-MVGDEAAYPMQSVVKFVLALSVLKRVD -QGAMNLEQIIRIRQEQLVKWSPLRERFPQGGFSLKELLRVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILKKGTQS -VLWNIMAGCSTGPERLKGLLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCL-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis granuli TaxID=267128 RepID=UPI0009586E5A ----LDDRIASLWRAFPGKTGIAIQRVDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD -AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE -YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN -TTASIPARMALMQAVSGAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis granuli TaxID=267128 RepID=UPI00082D43F7 ----LDDRIASLWRAFPGKTGIAIQRVDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD -AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE -YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN -TTASIPARMALMQAVSGAVAE-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Sphingopyxis TaxID=2614943 RepID=A0A1E4JR26_9SPHN ----LDDRIASLWRAFPGKTGIAIQRVDGEWAL-AQRGGDLFPQQSVSKLWVALTVLDAVD -AGRISLDQMVRIGPEDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -KAVRAFIADKGLGAIRFGPGERLLQSNYLADPIDGASPAAIASALTRLARGTLLSPASTE -YLLGVMSRTRSGPKRLKAGLPDGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN -TTASIPARMALMQAVSGAVAE-- ->[subseq from] class A beta-lactamase n=2 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000D00BA33 -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLSE -QGRLPLGHRITITRDQLRGHSPIRETFQGQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -VVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A166W7W3_ECOLX ------------------------------------------------------AVLLRSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTN--------------------- ------------------------ ->[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides sp. 2_2_4 TaxID=469590 RepID=C3QTD3_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQRQSLETQLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Dyella sp. C9 TaxID=2202154 RepID=UPI000DEFAFDC ------RVVDAYAARAPGTLGVAVLDLKTGATA-GVNADKPFPMMSVFKAPVAAAVLSRVD -AGTLSLDQRVTIHRSDVLSGSAVPARFRGEQFTVEQLLKAAVSESDNTAVDALLKVV-RP -DEVTAFLHAHGIDGLRVDQDEAGVAQAFLDDPRNRSTPDAAVMFLRKLGGGELLSPASTQ -HLLGLMAAQTI-PNRLRAGLPQGVRFADKTGTSGTAAYNDIGIATWPDGRVLIVAAFLLD -SPATPQARDALFATFARD----- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A414FKE5_9BACE ---SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALANYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKN -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=UPI000E7EDD4F ---SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=5 Tax=Bacteroides TaxID=816 RepID=A0A1Y4V0K2_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQRQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -NAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMIECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC49D2 ---SLEQKLLEIAQGASGTFGVTVKHLQTGETT-SINGNELFQLASTFKIPILATLYRDVE -AGKLSLDDRFKISEEDLVPGSGVLQEHLGVEVTVKDLAMLMIIVSDNLATDRLLKLV-GT -EQVNAYMRELGLENTHIHHSCWDLLSVFQADPRNAATSEDMAKLVELIAKKQVVSEQACD -GMLDILFRQQF-NSRLPYMLPAKTKVAHKTGTLSD-CVNDVGVIYLPDKGSFAISVLSKN -NP-TMEEGERTIGRLARAAYDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=B2CD48_ECOLX -------------------------------------------------VLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGCFL---------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. Leaf180 TaxID=1736289 RepID=A0A0Q5QE39_9FLAO ----TQMDVSKILYDKKATVAVSVLGFEKEYSF-DKNGDAKLPLLSVFKFHIAATVLHLVD -EGELALDQKVILTDAEMIPWSPIREKFPKGDLTLAELLEYTVAQSDNNGCDKLLKLIGGT -ETVQKFMDSKGVKDFQIKVNEEAMQQDRKNMYENFSSTKSAVRLLKSFYENKIISRKSTE -FLMNTMLSTSTGANKLKGWLPKNVRVAHKTGSSGKDAENDMGIVTLPNGKHYAIAVLISD -STETAEVNCGIIADISKVFYD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. (strain SKA58) TaxID=314266 RepID=Q1N8Q5_SPHSS ---KLLGEFERFATLSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID -AGDVRLDDQLALDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP -AAITHFVKGLGVDGLRVDSDTAHLLYAFATEIEDTSTPRAMLDLLTAYESGKALSADSTQ -RLFTIMAHCETGKGRIIGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK -DSKGHKSRDRIIAEAARAAYDYf ->[subseq from] serine hydrolase n=1 Tax=unclassified Novosphingobium TaxID=2644732 RepID=UPI001358CD9F ------QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWSLTSEFPLMVPVGSASSAVAPVRAGEYMTASRLIELMITRSNNYATDALLKVVGGP -KAVNAWVGRAGIDDWHIDRDIATLVRARVVDTRDSATPYAMVQLLSGIYQGKWLSPSSRS -VILGAMSRCVTGKRRIPAGLPEGAQVSHKTGSLNN-TSSDVGIVQTPDGRVFAVAIYVTG -QG-GRPGRESRIASIARTVYNGy ->[subseq from] class A beta-lactamase n=1 Tax=Algoriphagus resistens TaxID=1750590 RepID=UPI00071681C3 --nSLYSTIQQISDTSSGQLGVSILHLESGEKV-SLNGDKKFPMQSVYKFPIAMAVLQEID -KEKFSLDDSIAIHKSEYIPHSPIRDQFPEGVMTLRDILAYNVSHSDGTACDVLLRILGGT -EKAEKKIHGLGIKDIAISTTEMVQVAHDTIQYQNWSTPDAMNDLLVVFFKGKDLSENSRQ -FLLKLMSSNPWFDRRIKGLLPKETPLVHKTGTAATRATNDVGIITLPDQSHLVISVFISD -SYDSQSKRESIIASVSKAAFDHw ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium barchaimii LL02 TaxID=1114963 RepID=A0A0J7XND4_9SPHN ------QQLAAVANASQGRIGVAAMDLTSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWTLTSEFPLMVPVGSASSAVAPVRAGEYMSASRLLELMITRSNNYATDALLKVVGGP -KAVNAWVERAGIDDWHIDRDIATLVRARVVDTRDSATPYAMVQLLSGIYQGKWLSPSSRS -ALLGAMSRCVTGKRRIPAGIPEGAQVSHKTGSLNN-TSSDVGIVQTPDGRVFAIAIYVTG -QG-GRPGRESRIASIARTVYNGy ->[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium AT-5844 TaxID=1054213 RepID=H0A7W7_9PROT ---NAEAEIRRIAAYCQGEVGIAARHLGTGAEL-SVQGEARFPMASTIKMTLVLTILDLAR -QGRLALTDMVSIRPEEMTPLGPLGGEFPHDGLSVLNLLEATITRSDNSATDVLFRVAGGT -AAVQAHMHAIGLRDIEVKRTMREALCDYGHPNRDHATPRAMLALLARLWAGEGIEPAARD -TILAMMARTSTGATRIRARLPAGIAVAHKTGSGT-GTANDLGFLTLPNEGTVALVAYVKG -SPLPVEARDAVLADTARLVLDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter sp. OF09-27XD TaxID=2293112 RepID=UPI000E55DE4A ---TLQKQIRSILKDKKAMIGVAVLY-NGKITV-SVNDDQGYAMLSTFKFPLALAVCDYLD -RQKLPLETEIYVSKADLHPYSPLRDKQPEGDISIKELLRYCVSLSDNNACDILIRYIGGI -ERLQQYIADLGFPDMVIVATETQMHQQTGNQVLNRTRPSAAVLLFEQFLQKKLLSATYQD -FLEQILIETTTGANKLKGLLPSGTLVGHKTGSSDRNGDNDMGFVYLPNGNYFVIAVFIMD -SMEDDDTNASIIARISRTVYDHy ->[subseq from] Class A beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525J8T6_9CAUL --kRLNTEVAAIAARAPGVLGFGLMNLESGEFW-VRLGDRTFPMQSVFKLPLGTAVLSEVD -AGRLSLGETLTIKPEDLSPWSPIADAWPGRAYTVQELLEAAVSNSDNTAADLLMKRIGGP -GAISSWLQGKNVTEIRVDRYEREIQPAYMADPRDSATPEGMLGFLRKLDEGSLISPASTA -RLLTIMIGTPRGADRLKAGLPKDARFAHKMGTSGTAAFNDVSIFTLADRRSYAICAFLTG -STASDTERAALFAQLGHTAA--- ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter epoxidivorans TaxID=361183 RepID=A0A0M5KZ77_9SPHN ---SFERRIAQLADGDRGRIGVAAIDLATGEEV-AILGDQLFPMASTSKIAIAATYLELVE -KGKYSLTSEFPLMIPVSSARFSSSKAPVRKGMQAIDLIEIMITRSSNPATDALLAAVGGP -DKVNDWVRRQGIKEFSIDRDIATLVRAYYIDKRDAATPRAMVELLRGFYQGKYLSADSRR -VLLGAMSRTRTGKRRIVANMPSDARVSHKTGSLNN-TSSDIGIIEAPDGRAIAVAIYVTG -QG-SRLERENRIASIARALYDGf ->[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=unclassified Bacteroides TaxID=2646097 RepID=A0A412BVG8_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQRQSLETRLAIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Phenylobacterium immobile TaxID=21 RepID=UPI000B870DF0 ---ALNRAAEDISRRVPGVLGAGLMNLENGQSW-AFNGDRPFPMQSVFKLPLAAAVLAEIE -AGRLTLDERLVVRPEDLSPYSPIADAWPGRAYTVAEMLNAAVRDSDNTAADMLMRRIGGP -GAVTAWLVDKGVTELRIDRYERQLQTRYLSDPRDTATPRGMLDFLYKLDDGLIIGPVVRE -RLFAMMTGGRV-TSRLAAAMPAGASLLHKTGSSWNAATNDVGLITLADGRRYAAAVFLSG -ASLDDDARDAAIAELGRGMI--- ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5LYK7_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD -FIFQTMVECQTGQDRLIALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YG1 TaxID=2082188 RepID=A0A2Z6AFT8_9SPHN ---KLLAEFTRFSTLSDGTVGVAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALVD -AGEVQLDDQLALDPALASEGIAWMFNRPGATLSVDRLLELMLQKSDNNATDVLVARAGGP -QAITAFVTKLGVTGLRVDSDTAHLLYAFAMEPQDTATPTAMLDLITAYESGRALSAASTQ -RLFTIMAHCETGKARIVGMLPPGTAVAHKTGSLN-GTGNDVGIVRLPDGRRFAVVAFVMK -DSKGHVSRDRIIAEASRAAYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A174WVN6_9BACE ---SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJU6_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKK -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQA--------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium CG12_big_fil_rev_8_21_14_0_65_65_10 TaxID=1974094 RepID=A0A2M7HJI6_9SPHN ---NLGARIAAIADGSRGRIGVAAMDLTTGQTL-GVLDDQFFPLASTSKIAVAATFLEGVE -QGKWSLTSEFPLLWPLRSKSTRVAPVREGKYLPASELIELMITRSSNPATDALLRVVGGP -DAVNAWMRRNGISEFSIDRDIATLVRAIKVDRRDAATPRAMIKLLAMLHNGDVLTPVHRR -VILGAMERCRTGTRRIPALMPAGATVAHKTGSLNN-TSSDIGFITAPDGHTYAVAIYVTG -QG-SRSNRERRIAEIARELLDGy ->[subseq from] Class A beta-lactamase n=1 Tax=Chryseobacterium sp. CH25 TaxID=713559 RepID=A0A4Q1FU20_9FLAO ---EFKKIIETILANKKAEVGVSIITSGTKKEVtQINGNKPLPMLSTFKFPVALAVLHKVE -KGELSLQQKIYIKKEELLAYSPFRDKYPEGNLTLEDCIHWMMVYSDNNLTDILLRLIGGP -DYVQNFINS---KDIVIKNDEEGMHKDWDSQFINTITPNEAIRLLKEFYTGKILNKEHTK -WLYTAMLNNATGVKRLKGKLPKDIKVAHRTGTSFTGAVNNYGIIELSDKKRIYIAVFVHD -TYETFENSEAIIADIAKAAYDYy ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter odishensis TaxID=1155476 RepID=UPI000E716866 ----LERRIAQIANGRDGRIGVAAIDLATGEQV-SVLGDQLFPMASTSKIAIAATFLEGVD -QGRWSLTSEFPLLWAVRSQSTRVAPVREGEYLPASQLIDLMITRSSNPATDALLAAVGGP -AAVNDWARRAGLSGFSLDRDIATLVRTYHIDPRDAATPETMVRLLAGIYQGEWLSAESRD -VILNAMERTRTGRNRIRGMMPAGVTVSHKTGTLNR-MAGDIGIVEMPDGRAIAMAIFVTG -QSASRRLRDARIASIARALYDGy ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SN46_9BACT ---ELENRIDSPLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Uncharacterized protein n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3DZQ9_9FLAO ---SLINKINTITENKKAIIAISVLGFENHFKY-NKNSEKKLPMQSVFKFHIACAVLDWVD -KGKLSLDQKITLNKSNLLEWSPLRKKYPNGNVPLSEIIKQTVAFSDNNGCDILLKLIGGT -QTVQKFMDSKHINNFQIVFNEQQMHKDWNAQYQNYTTTASAAKLLKKFYDMKLLSKESTT -FLMNIMLATTTSLNKMVEQLPSKTPVARKTGASGTGAENEIGIITLPNGQHYALAIFVSD -STEPSMVNLRLISDISKAVWDHf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SS25_9BACT ---DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANNDDQYPLMSVFKFHIALAVLKKME -KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI -QNVNDFIKNLGIDRIQLIETEKSMEQDIRKTYNNWSTPLSVAQLLRKVYTEKVLSDEHFA -FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD -SKESDAANAKIMADIAKKVYSHy ->[subseq from] class A beta-lactamase n=1 Tax=Curtobacterium sp. B8 TaxID=95611 RepID=UPI0003B3DCDA ------------------------------------------------------------- ----ADLDTFVHFGRDDLLAYAPITSRSVDSGMTVRELIDAPLRFSDNTAANLLVERLGGP -ARVEEYLRSIGDRTTTVDRVEPDLNAATPGDPRDTATPEQFAVDLRRVVLGTVLGRSDRT -LLRDTMLDNTTGAATVRAGVDSAWPVADKTGTGEFGVRNDIAVVYPAGRAPIVVVVMTRK -DTPHAATDDALVAAATRTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=X5KBF1_9FLAO ----LKKTLESIISGKKATVGVSIMDPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQGFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 106C TaxID=1932667 RepID=A0A252E276_9NOSO ---SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVSMRSRD -RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR -PNND-PRAEKLISAISRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2QY42_9CYAN ---TLQRKLEAVAKESDGRVGICAEEIKSGVIT-CVNGDQRFSLQSVMKLVVAAAVMDAID -RGQMRLEDVVTVRKNDLSLVQPIADLVAERGTTVADLISGAVIESDSAATDLLFARVGGA -EGIRTFLKTKRISGLSVDRDEKHLQTAYLKDKRDTATPRGMVTFLSALASGKLLSVKSTA -HLLKVMQATVTFPDRLKAGVPEGWTLGHKTGTSLTAVTNDVGILTAPDGGTISVAVFVAE -SRRSSKERAKVIAATAKTITSSy ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter seohaensis TaxID=266951 RepID=UPI000C223CBF --nALEQTIAELADGSNGRIGVAAVDLSTGKTV-SVLGDQLFPMASTSKIAVAATFLEGVE -KGKWSLTSEFPLLLPRRSASSPRAPVYEGEYMKAIDLIEIMITRSSNPATDALLRVVGGP -EAVNDWMRRQGIEEFSIDRDIATLVRAQHIDRRDAATPNAILELLSGLYQGKYLSAESRR -VLLGAMSRTRTGKRRIPALMPASVKVSHKTGSLNN-TSSDVGILETSDGRAVAVAIYVTG -QG-SRLNREAKIAQIARALHDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FFI5_ECOLX ------------------------------------------------------------- ----------------------------------LAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLAS--------- ->[subseq from] Beta-lactamase n=1 Tax=Aureicoccus marinus TaxID=754435 RepID=A0A2S7TA23_9FLAO ---RLLDQIAAVDKNLDGQLGFSVLHLESGQEI-SHFGNKRFPMQSVYKFPIALVMLQAVD -RGEFSLDQMVEISPSEYIPHSPLRDRFPRGTMSIKELLRYNISESDGTACDVLLRLLGGT -KETEKKLHALGITDMAIATTEMVQMKNDTIQYQNWATPRGMNQLLKVFHQGEVLSEPSGN -LLKEFMSISTWFDRRLKGKLPPGTKLIHKTGTSNNRATNDVGIIELPNGEHLAVSAFIMD -SRDQHQERENAIAQAARLAYNFw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. Termitarium-T10T-6 TaxID=1839775 RepID=A0A1C4TP63_9ACTN -------DFEKLEREFDARLGVYAIDTGTGREV-THNDRDRFAYNSTFKALQAAVVLSTYS ---LDGMDKRVAYTREDLVANSPVTEKHVDTGMTLKELCDASVRYSDNTAANLLFDHVGGP -GGLDASLEKLGDDVTRMDREEPELSRWVPGEKRDTSTPRALAEDLRAFVLGKALGAPERA -QLTTWLRTNTTGDAV--------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. 106C TaxID=1932667 RepID=UPI000A39197A ---SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVSMRSRD -RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR -PNND-PRAEKLISAISRAAYQQf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium siyangense TaxID=459529 RepID=A0A420G0H7_9SPHI --nSLRKELHQIIATKNATVGISMKGIEIKDTL-SINGHLNAPLMSVFKFHIALATLNLVD -QGKLSLSQKFFIKKEDLHAWSPIRDEFPNGNLTLDQLLRYTVSHSDNNGCDILLDLIGGP -ETVQKFIHKQGIKDFTIKVNEQEMR-IWENLYINTTTPLASTELLEKFCAGQVLEKNTTN -YLYQLMVECSRGLTWMKAGLPEGTELAHRTGISDRAAMNDVGIFKLPNGNHIVLSVYLKD -ITEEREVTEKIIADITKSIWNYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3FHC6_ECOLX ------------------------------------------------------------- ----------------------------------LAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGGYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAESRRDVLAS--------- ->[subseq from] Beta-lactamase n=1 Tax=Legionella anisa TaxID=28082 RepID=A0A2Z3KSN3_9GAMM ---ELIKKIKDIEKKSNTVMGVTAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDSRNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -RYVAKRMNALGFKNISINRSIMEMFIRFEKDIRDTTTPDDMAKLLVKLYKKQALSESSTD -LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-2098 TaxID=1954171 RepID=A0A1Z4FQV5_9CYAN ---SLKTAVQNLVAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKIPILVAFFQDLD -AGKIRLDEMLTMQQPMIAGGSGNMQYKPAGTFTALEVVTKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVNMRSRD -RLLDIMRQTQR-DNLLPSGLGAGASIAHKTGDIGT-MLADAGLVDIPTGKRYIASVMVQR -PNND-ARAEKLISAISRAAYQQf ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides caccae CAG:21 TaxID=1263037 RepID=R5UU18_9BACE ---SLETQLKEAIKDKKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFGYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYQD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc carneum NIES-2107 TaxID=1973483 RepID=A0A1Z4HZQ9_9NOSO ---SLKTAVQNLAAANSLTPGVLLVDLDTGSYV-DINSAASFPAASTIKIPILVAFFQDLD -AGKIRLDEMLTMQQSMIAGGSGNMQYKPAGTYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTER-DNLLPSGLGTGATIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-ARAEKLISGISRAAYQQf ->[subseq from] Beta-lactamase n=2 Tax=Sphingopyxis sp. MC1 TaxID=1174684 RepID=N9WE64_9SPHN ----LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD -QGKLSLDRQVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -EAVRRFIAKKGLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ -YLMGVMSRTHSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD -TSASIPARMALMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia seriolae TaxID=37332 RepID=A0A0B8N725_9NOCA ------------------------------------------------------------- --------------------------------MTVSELCDAAITRSDNTAGNALLKLLGGP -EALTAFTRTLGDQVTRLDRWEPDLNTDIPGDERDTTTPAALAADYRALVLGDALPAPERR -QLTDWLLANKTGDARIRAGLPGDWRTGDKTGSGDYGTANDAAITWPADGSPVVIVVLSSK -PDAAATADNPLVAAVAKEA---- ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. Z76 TaxID=2304565 RepID=UPI001370C63A --rTLERRLAEYLDTLPVRAGVFVR-TDDGMEA-GYNADEEFPMLSTFKFPVALAVMAKME -RDGAEPSRPATVSARQLLPYSPMRERYGQRDTTLGQLLAYCVSQSDNNACDILIDYAGGI -DSVAHYVARTGVAPMRITATEQTMHTATERQRDNTSSPRAMVELLSLFREGRLLSQPYRD -TLMRYMTETSTGRDKLRAGISENAVSAHKTGSSDRTADNDVGIISLPDGRVCCIAVFVCD -SPMSDAENAAVVANVARMVCEEw ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. SYSU G00007 TaxID=2202251 RepID=UPI000D6E443F ----IQQQVEAIAAEGRGRIGVAAMDLDGGGQI-FINPDMAFPMASTAKIAVAATFLEQVE -KGNYRLDQQFPLMLPVRETISPEAPLRAGDLMTAQTLMELMITRSSNEATDGLLQVVGGV -ENVNRWLTRNGIAGQRLDHTMATLVRAKVIDTRTSSTPRAMIALLAAIDRGGVLSPESRA -VLLDTMTRTSTGKTRIRAGLPEGTLVAHKTGTLW-GVTDDVGIVRLPDGRHLAVAFFVTG -PEG-HAAHAKLIARMMRVIYDGy ->[subseq from] Serine hydrolase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=A0A1Y0RII7_9CYAN -----KTVVQNLAAANNLTPGVFLVDLDNGSYV-DINGSSSFSAASTIKIPILVAFFQDVD -AGKIRLDETLTMQKEMIVGGSGDMQYKPAGTFNVMEVATKMMTISDNTATNMLMTRLGGI -ESLNQRFRSWGLTTTAIRSPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMPSRD -RMLDIMRRTVR-NHLLPTGLGQGATIAHKTGDIGT-TLADAGVVDMPTGKRYIVSVMVQR -PNND-SRAEKLIGSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Scytonema tolypothrichoides TaxID=1233230 RepID=UPI0009FB2CDA ---TLQRKLEAVAKESDGRVGICAEEIKSGVIT-CVNGDQRFSLQSVMKLVVAAAVMDAID -RGQMRLEDVVTVRKNDLSLVQPIADLVAERGTTVADLISGAVIESDSAATDLLFARVGGA -EGIRTFLKTKRISGLSVDRDEKHLQTAYLKDKRDTATPRGMVTFLSALASGKLLSVKSTA -HLLKVMQATVTFPDRLKAGVPEGWTLGHKTGTSLTAVTNDVGILTAPDGGTISVAVFVAE -SRRSSKERAKVIAATAKTITSSy ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A326GHX9_9SPHN --sALEERIAQLADGSSGRIGVAAIDLTNGHTV-SVLGDQRFPMASTSKIAVAATFLEGVE -QGRWSLTSEFPLLLPRRSASSKVAPVYEGQHMKAIDLIEIMITRSSNPATDALLRVVGGP -KAVTNWVHRQGIRDWSIDRDIATLVRARHIDVRDSSTPTAMLELLSGLYQGKYLSAESRR -VLLGAMSRTRTGKRRIPALMPAGVKVSHKTGSLNN-TSSDVGFLETADGRTVAVAIYVTG -QG-TRLNREAKIAQIARALHDGy ->[subseq from] Penicillin-binding protein n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2QXT7_9CYAN ---------QNLAAANNLTPGTFLVDLDNGSYV-DVNASSSFSAASTIKIPILIAFFQDVD -AGKISLDETLTMTKRMVVGGSGDMQYKPAGTFTIMEVATKMITVSDNTATNMLIDRLGGI -ETLNQRFRNWGLTTTTIRNPLPDLEGT------NTTSPKELGKLMGMVNKGNLVSVASRD -RILDIMRRTVR-NHLLPSGLGSGARIAHKTGDIGT-TLADAGLIDMPTGKRYVLAVMVQR -PSND-PRAEKLISSISRAAYQQf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YR768 TaxID=1884365 RepID=A0A1H9U402_9SPHN ---KLLAEFTRFAALSDGTVGIAVRDLQTGETQ-AFNGDTLFPMASAYKVAVAGRIFSLID -AGDLRLDDKLVLDPALASEGIAWMFSRPGASLSVDRLLELMLQKSDNNATDVLVARAGGP -TAITAFVTKLGVTGLRVDSDTAHLLYAFSIEPEDTSTPTAMLDLMTAYEEGRAMSAASTQ -RFFTIMAHCETGKARIKGMLPPGTAVAHKTGSLN-GVGNDVGIVRLPDGRRIAMVVFVMK -DSKGHVSRDRIIAEASRAAYDYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Alistipes finegoldii TaxID=214856 RepID=A0A174CUZ0_9BACT ---QFESRLDEIVSEHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ -REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHHGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCGTTTGANKLKAGLPASTVIGHKTGSSDRTADNDVGYVVLPDGRRYCIAVFVTE -SEENDATNAAIAASASRAAYEYf ->[subseq from] Beta-lactamase class A n=2 Tax=Algoriella xinjiangensis TaxID=684065 RepID=A0A1I4Y847_9FLAO --tDLRQKLTEIISKQDAEIGISLRMIENNDSL-TINGNLNAPMMSVFKFHIALAVLDLVD -KGKLSLNQKIFVRKTDLHAWSPMRDDYPEGNLTLDKILRYTVSDSDNNGCDILIDLVGGT -KAIQDYIDKIDVKDFTIKVNEQQMST-WENCYLNTTTPIAMTDLLVDFYKGKILKKKSTK -YLIQLMEQNSRGTTWMKGQLPKNTVVAHRTGISNQNAHNDVGIITLPNGKHFVLSIFQKN -IKQTQEISAQTMAELTKVIWDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides finegoldii TaxID=338188 RepID=A0A1Q6HDZ1_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQAVALADYMD -KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYNNWSTPLAAAKLLEIFRRKTLFDEAYKD -FIYQTMVECQTGQDRLVALLDKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLENSKIIADISRIVYKY- ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. IPPAS B-1204 TaxID=2483793 RepID=A0A3M9YUW2_9SPHN ---NWQQRIAELADPAQGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAATFLEMVE -QGRYSLTSEFPLMMPVASAYSSTKAPRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP -AKVNDWMRRHGIAEFSINRDIATLVRAVHIDTRDAATPRAMVRLLSGLYRGEFLSDQSRQ -VLLAAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIECPDGRVIAVAIYVTG -QG-TKLAREQRIAAIARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc minutum NIES-26 TaxID=1844469 RepID=A0A367RYJ8_9NOSO ---SLKDAVQNLATTNSLSPGVFLVDLDTGGYV-DVNSSTSFPAASTIKVPILVAFFQDVD -AGKVRLDEMLTMQQDTVAGGSGQLQKPLGTQYNALEVATKMITISDNTATNMLIARLGGM -DALNQRFRSWGLTTTMIRNALPDLQGT------NTTSPRELANLMAMVNQGNFVSMRSRD -LMLDIMRRTQR-DNLLPSGLGTGARIYHKTGDIGT-MLADVGLVDTPTGKRYIAAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. 3_1_23 TaxID=457390 RepID=D7K728_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -NAVNKYIHSLGIRECAIAGTETAMHQDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIANISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. KVJ20 TaxID=457944 RepID=A0A1E2WEP5_9NOSO ---SLKNAVQNLADTNNLTPGVFLLDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNLQKSPGTQYAALEVATKMITISDNTATNMLITRLGGI -DALNQRFRSWGLTDTIIRNQLPDLQGT------NTTTPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DSLLPSGLGAGARVYHKTGDIGT-MLADAGLIGVPTGKRYVAAVMVQR -PNND-PRAEKLISSISRVAYQEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. HMWF008 TaxID=2056845 RepID=A0A2R7JSZ3_9SPHN ---ALAASVASLVRGFDGRVGVAVRSIDQGWTV-DSNGDQRLPQQSVSKLWVAMTVLDLRD -AGRLRLDDPVTVRREDLTLHQPIAALVKGEETTVGELLQRALTMSDNTANDRLLRFVGGP -SAVRDFLQRKGLSNIRFGPGERLLQARYVSDPPDGAAPVAIANALARLKRGDLLTKASSD -YLIGTMESSRTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLIAPDGKSYAIAVMIGD -TPKSIPERQALMQAVVASVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix sp. NIES-4075 TaxID=2005459 RepID=A0A218QGQ4_9CYAN ----LKSAVQNLALASNLTPGVFLVDLDSGAYV-DVNAGASFPAASTIKMPILVAFFQDVD -AGKIRLDETLTMQQDMVAGGSGNMQKPVGTQFTALELVTKMITISDNTATNMLIAKLGGI -EALNQRFRSWGLTTTVIRNKLPDLEGT------NTTSPKELGNLLALVNQGNLVSMRSRD -RLLDIMRHTEK-DTLLPSGLGVGATVAHKTGDIGT-MLADAGLVDMPTGKRYIAAVMIQR -PNND-PRAEKLISAISGITYQQf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Aquimarina sp. RZ0 TaxID=2607730 RepID=A0A5B1B3G0_9FLAO ----LRKRIEKILEDKSTTVGIAIRGINPRDTI-SINGNKRLPMQSVFKYHLALAVLHQVD -QGKLSLDKVISMDKELLESWSPLRKRYPNGGVTLADILKTTVAWSDNVGCDILFKLVGGT -DVVQSYIHNIGIKDIAIVHTEIAMQSEWQNQYENWTTAKAANQILQLFFEDNLLSNQSYI -FLLDVLKSTKTGKKSIKGLLPKETIVAHKTGYSGTGALNNIGIIFLPDDSYFYLSVLVSD -SKESDETNQRIIAEIAKLTWDYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=A0A4S2AV71_9BACE ----LEAQLKEAIKDKKAEIGIAVI-IDGKDTI-TVNNDNHYPLMSVFKFHQALALADYMA -KHKQSLDTLLKIEKSDLKPYSPLRDKYPQGEMSIADLLRYTLQQSDNNACDILFNYQGGT -DAVDKYIHSLGIQDCAIVGTEAAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD -FIWQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRTYSIAVFVKD -SEESFADNSKIIADISRIVYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP49 TaxID=1144307 RepID=J2L9V4_9SPHN ---HLLAEFDRFAALSDGTVGIAAMDLQTGEIQ-ARNGDTLFPMASAYKVAVAGKILSLVD -AGSLRLDDRLALDPALASEGIAWMFSRPGSTLPVSQLLDLMLTRSDNNATDVLVARAGGP -QAVNDWVAALGVHGLRVDSDTAHLLYDFMLDPRDTATPLAMTALLAAYEAGRALKPESTQ -LLFTIMGHCQTGKARLAGMLPPGTAIAHKTGSLN-GIGNDVGIINLPDGRRFAITVFVMK -DSRGHVSRDRIMAEAARAAYDYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. HF-5300 TaxID=2594945 RepID=A0A553KVB4_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDTHYPLMSVFKFHQAVALADYMD -KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEVTHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD -FIEQTMVECQTGQDRLVALLDKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLENSKIIADISRIVYKY- ->[subseq from] class A beta-lactamase n=1 Tax=Mastigocladus laminosus TaxID=83541 RepID=UPI0009082A83 ----LEARVQSIGRAFNGDVGIAVRDVSTGWTT-AYDGDTFFPQQSVSKFWVQLTALDRVD -QGKLDLASSVTVGRDDLTLHQPIRAMVLKNGTTLSDLMHRAITQSDNTANDFVLWKAGGP -EAVRAFLQKNGLDGIRFGPGERLLQTRYIADPMDGATPRAVVEALARLKRGELLSPASTS -RILAIMSNTRTGAQRLKGGLAPGWSLAHKTGTGQQAGYNDIGLLTGPGGRSYAVAVLIRR -TSAPLPQRMAMMQNVTRAVID-- ->[subseq from] Uncharacterized protein n=1 Tax=Emcibacter congregatus TaxID=2043170 RepID=A0A2G4YVP2_9PROT ----LLQEIRRIAERNRGNVGVAVRHLETGKLL-SFNGDAQFLMASTYKIPIAVRILQLVD -QGKLSLDDLIEIRKDEYVSWSIIADRFNRGPISISNLMELMLVLSDNTATDVLLRIAGGG -KAVTAMLRDQNIKEMTVSRGTKDLIIYLSRNNDDKAEPNAMLQLLDNIWTGDILTNSSKK -ILQKIMERCETGKGRIKGKLPKNTIVMHKTGTLDHGVINNVGVIQLPNKGNIAIVVYTKD -AGKGIEFNEEIIADISQAVYNYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5B4X5_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIANISRIVYEY- ->[subseq from] Beta-lactamase BRO-2 n=2 Tax=Moraxella TaxID=475 RepID=A0A066UD53_9GAMM ----LKEILPIWENKFNAKIGMTIIA-DSGEIS-SHRGDEYFPVNSTIKAFIASHILLLVD -KGKLDLNEKIIIKESDLIEYSPVCKKYFNENISISELCEATITLSDNGSANILLDRAGGL -TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTRSLKALITDNILSNQSKE -QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKSYFVSLFITQ -PHDGKNQKDEIMAQIGKEIY--- ->[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SRN4_9BACT --nALQNELTTLVEVAKGRVGVGAVLVETGQTV-YLDRKGQYPMQSVYKLPIAMAVLKMID -DGKVKIDQDVSITPDDFVRHSPIRNVNPQGTMNVYGIMRYSISESDGTASDVLLDLAGGP -DAVMNYLKSIGITEVIVADSEKSISKDWETQYRNWATPEASIELLEHLYGRRALSEQSTN -LVLDFMTNSDTGGRRIKRGLPEGASIAHKTGTGGTGATNDMGIVTLPDGNHLLIVIYIAD -SKETGFARQQLFGDVARAIIEKw ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. SG707 TaxID=2586996 RepID=UPI001445EFB8 ----FEARLAQLAGASQGRIGVAAVDLSSGRGV-SVMGDQPFPLASTGKIAVVATFLEGVD -QGRYKLSDRFPLMMPVPSASTAVAPVRPGAMLSAEQLIELAITRSDNHATDALLAAMGGP -QVVTRWLRRNGINGIRLDRDIATMVRARKIDLRDSTTPQAMAVLLAGLYQGQWLSAQSRE -VLLGAMARCRTGIHRMRAALPGDAMVGHKTGTLSN-TSSDVGLIRSSDGRTIAVAIYVTG -QG-GKPGRDQRIASITRAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. SCN 63-17 TaxID=1660120 RepID=A0A1E4MZ94_9SPHN ----FEARLAQLAGASQGRIGVAAVDLSSGRGV-SVMGDQPFPLASTGKIAVVATFLEGVD -QGRYKLSDRFPLMMPVPSASTAVAPVRPGAMLSAEQLIELAITRSDNHATDALLAAMGGP -QVVTRWLRRNGINGIRLDRDIATMVRARKIDLRDSTTPQAMAVLLAGLYQGQWLSAQSRE -VLLGAMARCRTGIHRMRAALPGDAMVGHKTGTLSN-TSSDVGLIRSSDGRTIAVAIYVTG -QG-GKPGRDQRIASITRAIYDGy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9B5Y5_9BACT --tALQQKISVIAADARGKVSVACSLPGSDLNC-DLNPHTRPPMQSVFKLPLVMTSLHLIE -ERKFSLDQPVRFLPSDRILHSPLQDKYPEANIPLRELLRLAVSLSDNSAADLVLRVIGGP -EVVQRYMNSIGVDGFQLKDGERGLHGDVAAQYRNWFEPASAVKLLRRISDDSPLSAEHTA -LLLAWMKDTPTGAHRIKGELPEGTNVMHKSGTSGSGATNDIGLIALPNGRRLAIAIFVTD -AAADDATRDAVIARIAKAAYD-- ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Bacteroides TaxID=816 RepID=A0A5M5EKY6_BACOV --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKN -SEENNQANSKIIANISRIVYEY- ->[subseq from] Beta-lactamase BRO-1 n=12 Tax=Bacteria TaxID=2 RepID=BLA1_MORCA ----LKEILPIWENKFNAKIGMTIIA-DNGELS-SHRGNEYFPVNSTIKAFIASHILLLVD -KEKLDLNEKIIIKESDLIEYSPVCKKYFDENISISELCEATITLSDNGSANILLDKIGGL -TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKE -QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKPYFISLFITQ -PHDGKNQKDEIMAQIGKEIY--- ->[subseq from] Uncharacterized protein n=1 Tax=Alistipes sp. CAG:29 TaxID=1262694 RepID=R6Z1Q2_9BACT ---QFESRLDEIVSEHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ -REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHHGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCGTTTGANKLKAGLPAEIVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE -SEENDAANAAIAAAVSRAAYEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Prauserella rugosa TaxID=43354 RepID=A0A660CCF4_9PSEU ------------------------------------------------------------- ------------WTDEDLVLNSPVTENTVRNGLTVAQLAEATVTVSDNTAANVLMREFGGP -AAVTAFARSLGDRVTRIDRWEPELSTGTPGDERDTTSPRSIAGTYASLVVGRALSRPDRE -RLTTWMLANQTAGPVFGAGVPAGWALADKTGAGWYGARNDVGITWTPDGAPLVIAAFTHG -RAYEDDSLDEPLAAIAESAC--- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5C2Z6_BACOV --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDTHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNVCDILFNYQGGP -GAVNRYIHSLGVRECAIIGTETAMHEDLNLCYQNWTTPLAAAELLEIFHKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. CCH11-B1 TaxID=1768781 RepID=UPI00082BCD9D ---KLLGEFARFATLSDGTVGIAVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALID -AGQLKLEDQLALDPALASEGIAWMFSQPGAHLSVDRLLQLMMQKSDNNATDVLVARAGGP -QAITQFVTGLGVRGLRVDSDTAHLLYAFAAEPEDTSTPTAMLDLVTAFEAGRALSPASTQ -RLFTIMAGCETGKARIVGMLPPGTAVAHKTGSLN-GVGNDVGVVRLPDGRRFAVVMFVMK -DSKGHVSRDRVIAEAARAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Phenylobacterium sp. CCH12-B4 TaxID=1768784 RepID=UPI00083A2012 --------ISAIAGAAPASLGVGLSNLESGQTYiRLGQHRRFPMQSVFKLPLAAAVLAEAD -AGRLMLTEPFVLTEEQLSPVSPIAAGWPARRYTAQALFEAMVVDSDNTAADVLMKRIGGP -GAVTAWLTARRVPEVRVDRYERELQPRYMSDPRDTTTPRGMLELLQMLDRQELVSPASTK -RLLELMGRTRRGVGRIRAGLPRDAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG -STLDEAGRDRIIAEVARAAL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649VZ78_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDGTEPTLNTAIPGDPRDTTTPRAMAQTLRNLTLGK-------- ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Alistipes onderdonkii TaxID=328813 RepID=A0A656Q3R1_9BACT ---QFESRLDEIVSEHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ -REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHHGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCGTTTGANKLKAGLPASTVIGHKTGSSDRTADNDVGYVVLPDGRRYCIAVFVTE -SEENDATNAAIAASASRAAYEYf ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia gladioli TaxID=28095 RepID=UPI000D009432 -hdALQATLERFAQAAPGTLGVVVLDLERPARW-QVNGTLPFPMMSVFKAPLGATVLDLSE -QGRLPLGHRITITRDQLRGHSPIRETFQSQQFTVDTLLRAAVSDSDNTAADALLRAVGGP -VVVTGWLRAHGIEGMRVDMDEGEVSRAYLADPRNRTTPLAAAEFLRKLAGGELLPPTATR -RLLGLLRDQTQ-PRRLRAGLPPGVTFADKCGTSLTAAFNDIGILTWPDGHRLVIAAFLSA -SRASRAERERLFADLARAVAS-- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A53C11 ------------------------------------------------------------- --------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHGTRLDSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. T09 TaxID=1932621 RepID=A0A252E654_9NOSO ---SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSATSFPAASTIKIPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTQK-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-LRAEKLISAISRAAYQQf ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides finegoldii CL09T03C10 TaxID=997888 RepID=K5CAA1_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQAVALADYMD -KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD -FIYQTMVECQTGQDRLVALLDKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLENSKIIADISRIVYKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingopyxis flava TaxID=1507287 RepID=A0A1T5A0P8_9SPHN ----LEQRIFELWRSFPGKTGIAVQRIDGEWTL-QQRGDELFPQQSVSKLWVALTVLDAVD -RGALTLDRKVSITPADLTLHQPIAARVRAEGMSVRELIETAITHSDNTANDSLLRTVGGP -DAVRRFIAAKDLGAIRFGPGERLLQSNYLANPVDGASPSAIARALTRLARGTLLSPQSTD -YILGVMSRTRSGPNRLKAGLPSGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS -TTASIPQRMVLMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Dysgonomonas mossii DSM 22836 TaxID=742767 RepID=F8WVR0_9BACT ----LRNKIQKIIEGKDATVGVALI-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN -KNNLTLDHQVYVKKSDLLPHSPLRGDYPHGELSVADLIKYTVSNSDNNACDILFRLVGGT -AEVDKYIRGLGLSEFAIAATEEEMHGPWDVQYTNWSTPYTTAQVLEIFRTQNILPQPSHE -FLWNALAGTTTGENKIKELLPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD -SMESNDVNCGIIAQISKAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HTW1_9BACT --eRLEAELARFEPLSGGTLGIHAVHLETGRSV-GLNADDAFPMASTYKVPMAYQLLRRVD -AGEVRLDSLVHLQQHHFSPGSGTLSDFIQPGLSVRNLLELTLLISDNTATDLILEIAGGG -EAVTSAMQDAGFGGVRVDRSTLQLIAAFEMDVRDTATPRAMASLLEAVWRDEGLSPESAG -LLRDIMERCRTGEGRIRGLLPDFVTTANKTGTIG-GTLNDVGAIELPDGGTVLVAAFIKG -SDQPNPRREAALAGAVRAIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A521PVR8_9CAUL ---------------RPANLGVGLINLESGETF-VFNGDRRFPMQSVFKLPLAAAVLAEID -AGRAVFTEPFVLLETQLSPFSPIAAAWPGRRYSLRELFEAMVIDSDNTAADVLMKRIGGP -GAVTAWLAGRHVAEVRVDRYERELQPAYMADPRDTATPLGMLDFLQMLDRQELITPASTR -LLLQLMGRTSRGNARIKAGLPGNAFLAHRPGTSGSTAHNDVGIFTLADRRSYALAVFLSG -ATLDDAGRDRIIAEVARAAVR-- ->[subseq from] Beta-lactamase, putative n=2 Tax=Coleofasciculus chthonoplastes TaxID=64178 RepID=B4W2U5_9CYAN ----LKAQVQTLVAKNKLQPGVFVVDLDTGAYL-DWQSHSIFPAASTIKVAILVAFFQEVD -AGKIRLDEPLTMEPEMIAKGSGDMQQKPGTQYSALEVATKMITISDNTATNMIIHRLGGI -QAVNQRFISWGLTATAINNPLPDLEGT------NTTNARDMANLLYKVNQGELLSLRSRD -RLLDIMQRTVN-NSLIPQGLDSGATVAHKTGDIGS-VLGDVGIVDMPTGKRYLIVTLVKR -PHND-ASASELIRNLSRTVYDYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8Z8_9BACT ---SLQKDLQRVVTESDGKVGICSWSLAASEAV-CINGLERFPLQSVMKLIVSAAVMDAID -QKRMKLEDLITVKPEHASPPQEFADLVRKKGVTVEELMRRSIVDSDSTSIDILIEKLGGM -RTVQSFLKAKNITDIRIDRNERDLQSTYLKDPRDTATPLGMVKFLKALAEGKLLSRTSTE -KLLSIMEMTVTGPDRLKAGLPPGWKIGHKTGTSFAAATNDVGILTAPNAARIAIAVFVTD -SRHSPDERALVIAKAAKAVTGSf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. EL138 TaxID=2073156 RepID=UPI000D698353 ---ALERQIAELWRTFPGKTGIAIKSIDGGWSI-GHRADQNFPQQSVSKLWVAMTLLDKVD -QGRISLSDSIRIGPDDLTLYQPLAAEVKREGKSVYTLLERALAYSDNTANDALLRHAGGP -EAVNDFIRRSRLGKIKFGPGERLMQSDYLADPIDGASPDAIVNALDQLARGKLLSANSTQ -LLQSILKRTRSGPKRLKAGVPSDWEFLHKTGTGQSTGYNDVGIMTAPDGSRYAVAVMLGD -TTAPIPERMRMMQAVTRAVASY- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. T09 TaxID=1932621 RepID=UPI000A36AA59 ---SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSATSFPAASTIKIPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVNMRSRD -RLLDIMRQTQK-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-LRAEKLISAISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Legionella sp. TaxID=459 RepID=A0A2H9SXB9_9GAMM --kDLLKKIRAIEQQNHTTLGITAIHIEHNKKI-AHNSAQRFFMASTIKVPIAIALLHRVD -QKKEALNRVIKMDTKNSVPGSGNLHYVFEKKMSLQQILKHMLVHSDNSASDTVLKAVNGP -QYVTQYMYALGFKNMVISRSILEMLLKFQKDYRDTTTPDEMARLLVKLQKQQILSASSTQ -LIMSIMEQCRTGRSRIKGLLPSYVKVAHKTGTWSYRFASDVGVITLPNNGHVAIAVYVKS -QSASDYPRSRSIALASRAIYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=3 Tax=Bacteroidaceae TaxID=815 RepID=UPI00125F0659 --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSQGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=UPI000AC7F63E ------------------------LDLNSVKILeSFRPEERFPLLSPLKVLLCGAVLARID -AGQEQRGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITSSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWM------------------------------------------------------ ------------------------ ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas indica TaxID=941907 RepID=A0A1X7H068_9SPHN ----LEARVQSIGRAFNGDVGIAVRDVATGWTT-AYDGDTFFPQQSVSKFWVQLTALDRAD -QGKLNLANSVTVGRDDLTLHQPIRAMVLKNGTTMSDLMHRAITQSDNTANDFVLWKAGGP -DAVRAFLHKNGLDGIRFGPGERLLQTRYIADPMDGATPRAVVEALARLKRGELLSPASTS -RILGIMSNTRTGAQRLKGGLAPGWNLAHKTGTGQQAGYNDIGLLTGPDGRSYAVAVLIRR -TSAPLPQRMAMMQDVTRAVID-- ->[subseq from] BRO-2 n=4 Tax=Moraxella TaxID=475 RepID=Q49095_MORCA ----LKEILPIWENKFNAKIGMTIIA-DNGELS-SHRGNEYFPVNSTIKAFIASHILLLVD -KEKLDLNEKIIIKESDLIEYSPVCKKYFDENISISELCEATITLSDNGSANILLDKIGGL -TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKE -QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKPYFISLFITQ -PHDGKNQKDEIMAQIGKEIY--- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SCN 62-14 TaxID=1660099 RepID=A0A1E4AYL7_9SPHN ---SLEARIADLANPARGRIGVAAVDLTTGEEV-MVLGDQLFPMASTSKVAVAATYLEMVD -RGQASLTSEYALLLPVASPSSPKAPVRPGNYMPAIDLIEIMITRSSNPATDSLLAAVGGP -ATVTSWMRRHGFNDFSINRDIATLVRASRIDPRDAATPRTMVRFLQGLYRGDFLSPQSRQ -VLLGAMSRTVTGKRRIPAQMPYDARVSHKTGSLNN-TSSDIGLIETPDGRVIAVAIYVTG -QG-TRAAREDKIAEIARALYDGf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. AM56-10ce TaxID=2302926 RepID=A0A373GA16_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLGTRLPIKKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIANISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium sp. Z007 TaxID=627495 RepID=UPI000B49BAAD ---KLLGEFARFAALSDGSVGIGVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRILALVD -AGEARLDDQLALDPALASEGIAWMFSRPGATLSIDRLLELMLQKSDNNATDVLVARAGGP -QAITGFVNKLGVTGLRVDSDTVHLLYAFANEIQDTSTPAAMLDLIAAYESGRALSAASTQ -RLFTIMANCETGKKRIVAMLPPGTAVAHKTGSLN-GIGNDVGVVRLPDGRRFAIAVFVMK -DGKGHVARDRIIAEAARAAYDYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=A0A3L7Z1Y8_9BACE ----LEAQLKEAIKDKKAEIGIAVI-IDGKDTI-TVNNDNHYPLMSVFKFHQALALADYMA -KHKQSLDTLLKIEKSDLKPYSPLRDKYPQGEMSIADLLRYTLQQSDNNACDILFNYQGGT -DAVDKYIHSLGIQDCAIVGTEAAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD -FIWQTMVECQTGQDRLVALLDKKVTVGHKTGTGDHNGCNDIGFVLLPDGRTYSIAVFVKD -SEESFADNSKIIADISRIIYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavimarina sp. Hel_I_48 TaxID=1392488 RepID=UPI0005615695 ---DLKTSIENILKGKKAQVGVAIASNKSKDAI-NINNDFQYPLQSVFKFPIALTILSEVD -KGKFSIDQPIEISKNELAAWSPIKDKFPDGTLTLGEILAYTVAQSDNIGCDILLKLIGGT -ATVETFLKDNIIEDIVIKVNEQQMHEDWAAQYKNWGKPTALNELLIKAYRGQMLSHKSHE -LIWKIMRETTTGTKRLKGNLPQHVAVAHKTGTSGTRATNDIGVIELPDGEVIFISVLVVN -FQEQPETNEQLIAKISKAAFDYy ->[subseq from] Beta-lactamase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4IMZ9_9CYAN ----LKTVIQNLAAANNLTPGVFLVDLDNGGYV-DVNGSSSFSAASTIKVPILVAFFQDVD -AGNIRLDETLTMQKEMVVGGSGDMQKPVGTQFTAMEVATKMMTVSDNTATNMLIARLGGM -QVLNQRFQSWGLTTTAIRSPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMSSRD -RMLDIMRRTVR-NHLLPTGLGPGATIAHKTGDIGT-TLADAGVVDMPTSKRYIVAVMVQR -PNND-ARAEKLISSISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. RF31YmG TaxID=1932668 RepID=A0A252D5Z8_9NOSO ---SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVNMRSRD -RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR -PNND-PRAEKLISAISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Mastigocladopsis repens TaxID=221287 RepID=UPI0002D9F5C8 ---SLKTAVQNLAAGTNLTPGVFLVDLDNGSYV-DVNGSSSFSSASTIKIPILVALFQDVD -AGKIRLDETLTMQKEMVVGGSGDMQKSAGTQFTVMEVATKMMTISDNTAANMLIGRLGGI -EVLNQRFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNLMAMLSKGNLVSVSSRD -RILDIMRRTVR-NHLLPTGLGQGATIAHKTGDIGT-TLADAGLVEMSTGKRYIIAVMVQR -PNND-ASAEKLIGSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012905CE1 ------------------------------------------------------------- ---QEQLGRRIHYSQNDLVEYSPVTEKHLTNGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGE-------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Swaminathania salitolerans TaxID=182838 RepID=A0A511BUH1_9PROT ---DLARLARNYERRSGGRIGIAIRGLSPGRMT-SWRGHERFLMCSTFKVSLVACILARCE -QGADDLTLRLPFTDEDIGTWAPVIRENRETGLSLAALCAGAITVSDNVCANLLLRHLCGP -RKLTQFWREEGDRVSRLDACEPALNHPAADPLANTTSPCAMTGTLDHLLYGSALNTDSKR -LLRGWMTHCRTGTSRLRSGFPPGWTCGDKTGSNGKDIAADIAFARPVDNHRVVISTYTAG -GAASPALLDATFREIGALAT--- ->[subseq from] Uncharacterized protein n=1 Tax=Alistipes sp. 58_9_plus TaxID=1896970 RepID=A0A1Q6FEK9_9BACT --------------DIPARVGIYAED-SDGRTL-TYRADEMFPMLSTFKIPVAISVLKRTE -VTHTPLSHRIAIAAGQMRPYSPMLKRHPQGWATIDSLLSYAVSMSDNNACDILIDYAGGI -KAVAKTIEQAGIYPMTISATEEDMHRDIDNQRINVCSPRAAAYMLGRLANGELLTSASTE -ALIRHMTRTETGIDKLHAGLPQHIVMAHKTGSSDRTADNDIGIVFLPDGRSYIITVFIAD -SGLDDKANAALTAEISRIVYEAf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroidaceae bacterium TaxID=2212467 RepID=UPI0011DC9A2B --tQLETQLKEAIKGKKTEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQKRSLETRLPIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRSYSIAVFVKD -SEENNRANSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=A0A328ASL9_9CAUL ---ALEAEVGRIADRCPGVLGVGLMNLENLETW-LLNGERPFPMQSVAKLPLGAAVLAEME -AGHLRLDEVVQVQETDLSPFSPVADAWPQRTWTVRELLAEAVGQSDNTAADLLMRRVGGP -GAITAWLVSERIEEVRLDRYARELQPRYMADPQDTATPRGMLNFLQKLDSGQLVSPASAQ -LLLTLLKQNTAGATRLRAGLPPNASLFHKSGTSRNPATNDVGVFTLPNNRSYAIAVFLSG -TSLDGVALDQIIAEIARAAVR-- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. RF31YmG TaxID=1932668 RepID=UPI000A3AB757 ---SLKTAVQNLAAANNLTPGVLLVDLDTGAYV-DVNSAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQQMIAGGSGNMQYKPAGTYTALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLLAMVNQGNLVNMRSRD -RLLDIMRHTER-DTLLPSGLGAGASIAHKTGDIGT-MLADAGLVDISTGKRYIAAVMVQR -PNND-PRAEKLISAISRAAYQQf ->[subseq from] Beta-lactamase n=5 Tax=root TaxID=1 RepID=F3QIV7_9BURK ---DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANNDDQYPLMSVFKFHIALAVLKKME -KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI -QNVNDFIKNLGIDRIQLIETEKSMEQDIRKSYNNWSTPLSVTQLLRKVYTEKVLSDEHFA -FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD -SKETDAANAKIMADIAKKVYSHy ->[subseq from] class A beta-lactamase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012FA55F1 ---RLEQELFRLSNLSAGKVGICAVHLESGKTI-TQNGKDHFPMASSYKVAIATQLLSRVD -SGSITLAQLVPILKTDFHPGSGMLSERFNWPLSVRSLLELMLLISDNSATDLCLRLAGGP -AAVNACMKRLGVEGLQVNRPTAWLIAAFENDIRDTSTPEAMTLLLTKLYTQPVLKPDSKT -LLLDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIITLPGDGHVAISVFVKS -SKKEGPVRERTIAEVTRTIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides finegoldii CAG:203 TaxID=1263045 RepID=R6RUE9_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIQYPLMSVFKFHQAVALVDYMD -KKRLPLGTLLPIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD -FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLENSKIIADISRIVYKY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI001370E3CA -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKVLVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. GV013 TaxID=2135688 RepID=A0A4R7DFZ5_9SPHN ----IEQQVAAIIAQGRGRIGVAAMDLDGGGQI-MINGDMPFPMASTAKIAVAATFLSGVE -QGRFRLDQSFPMMVRIAQPRGAIAPVRAGTVMSAQGLMELSITRSNNEATDGLIAAVGGI -ESVNAWLARTGIAGQHLDHTMATLVRARVIDTRTSSTPRAMIALLAAIDRGGALSPQSRA -VLLDTMTRTSTGRNRIRAGLPEGTLFAHKTGTLA-GVTDDVGIIRLPDGRHLAIAIFVTG -PE-NHTSQAGLIAQIAQVVYNGy ->[subseq from] UPI001446751E UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI001446751E ------------------------------------------------------------- --DARALAELVRYSRADLLPGSPVTGEHLGRGLSLAALCEAAVRHGDRTAGNLLLRRLGGP -GALTRFARSVGDRVTRLDRWEPELNSAEPDRRTDTTTPYAIARTYAHLTVGDALGTADSC -LLTGWMRQHTAGPARFRAGLPAGWLLADTTGGGPYGTGHDVGIVWTPEGTPLLLACLTRG -AEPGEEPDDALLAETAALLA--- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides acidifaciens TaxID=85831 RepID=A0A4Y9GVL0_9BACE ----LEAQLKEAIKDKKAEIGIAVI-IDGKDTI-TVNNDNHYPLMSVFKFHQALALADYMA -KHKQSLDTLLKIEKSDLKPYSPLRDKYPQGEMSIADLLRYTLQQSDNNACDILFNYQGGT -DAVDKYIHSLGIQDCAIVGTEAAMHEDLDLCYQNWSTPLAAAELLEIFRREPLFAKEYKD -FIWQTMVECQTGQDRMVALLDKKVTVGHKTGTGDHNGCNDIGFVLLPDGRTYSIAVFVKD -SEESFADNSKIIADISRIVYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A1G8I3R0_BACOV --sKLETQLKQAIKDKKAEIGIAVI-INGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KKKQSLDTRLPIKKPDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -GAVNRYIHSLGVRECAIIGTETAMHKDLNLCYQNWTTPLAAAELLEIFRKKPLFAKVYKD -FIYQTMVECQTGQDRLVALLDKKVTVGHKTGTGDRNGCNDIGFVLLPDGRIYSIAVFVKD -SEENSQANSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. HGC4 TaxID=1658009 RepID=UPI0006826B54 --nELRKNIQSIIENKNATVGVAII-FNGKDTL-TVNNQYRYPTMSVYKFHQALAVLDNLN -RRNLPLDQQIYVSKAALQPHSPLREARPEGNMPIKELLQYSVSQSDNNACDILFDFLGGP -NYVEKYIKSLGIMQIAITATEQEMHDDPNKQYANWTTPYAAVELLEKFKQQDWFPSQSKS -LLWDALVETSTGKDKIKGLLPSGTVVGHKTGNSFRNADNDLGFIELPNGKQLSIAVFIVN -SMEDDKTNAAIIAQISKAAYDYy ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=2 Tax=Sphingobacterium lactis TaxID=797291 RepID=A0A1H5Z0K3_9SPHI ----LTAKIEQIIKAYDAKVGVAVHNQEFTEHH-FVNKDHKYPMQSVFKFHLGIAVLNQVD -SGKLRLDQDVVITKADVSNYSPIREKFPNGTMPLSQVLHHTIAQSDNVGCNVLFRMLGGP -DQVQAYFEKQGYTGIAIRNDESEIQGDWEVQFKNWIDIETSNKILYDYYTNDQLSESSYQ -FLWDTMRGTSTGRDRIKGLLPAGTVVAHKTGYSGQNAVNDIGVVTLPNDKVFYITVLVTD -AKEPEPNCAKIIAEVAKAAYDHy ->[subseq from] Beta-lactamase n=2 Tax=Akkermansia TaxID=239934 RepID=A0A5B5WI01_9BACT -------AIREIVRPLKAHVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD -QGVLDLDQKVKVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP -ANVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPTAMTSLFRMFDEGKILKKDTQL -FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN -SKDSPAVCEGTIASVARWLCTEw ->[subseq from] Uncharacterized protein n=1 Tax=Leptolyngbya sp. 'hensonii' TaxID=1922337 RepID=A0A1Q8ZIY4_9CYAN ---ALKTEVQALTAQNGLTAGVFFVDLDTGAYI-DLNGDSTFSAASMIKVPILVAFLQDVD -AGKIRLDEMLTMRPDLIGSGSGVIQYRTGTQFTALEIATKMIVISDNTATNMLIDRLGGI -AALNQRFQSWGLTGTLVYNLLPDLEGT------NVTRPKELATLMFRVSQGDLLSIRSRD -RMLDIMRRTET-DTLLPRGLDDNATISHKTGDIGS-MVGDVGVIDAPNGKRYVAVAMVKR -PHND-SRAQEMIRRISRAAYQAy ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium subterraneum TaxID=48936 RepID=A0A0B8ZKX3_9SPHN --qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNADMPFPMASTAKIAVAATFLDLVE -KGNARLDQQFPMMMPVRETGARSAEAPLRSGMTAQSLMELSITRSHNEATDGLIQAVGGY -DKVNRWLTSKGITGQRLDHTMATLVRARVIDVRTSSTPRAMLALLAAIDRGNALSPESRA -VLLDTMTRTSTGKNRIRAGLPAGTLVAHKTGTLF-GVTDDVGIVRLPDGRHLAVVFFVTG -PEG-HTAHAGLIARMMRTIYDGy ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWB2_63_22 TaxID=1797929 RepID=A0A1F9SHD1_9BACT --qEMVADLEKVSRAYRGRVGVYIKDLETGRTW-EYNADRLFPSASLIKVPIMAAVFEKMR -LGAFTLDTQIKLTRRERVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATRMLIDYV-GM -DYLSVAFRELDLEHTNITQEGMSLKSG-RVARENYTTAREMASLLERIYAGELVNRESSE -FMLDVMKHTKS-RSRLRRGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE -VP-SYSSAKIFISKVAKLTYHYy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZR2_9BACT ---DLSSDIQEVIKGKKAQVGVAVLY--KDDAV-TMNNDGQYPLMSVFKFHIALAVLKKMQ -QEGILLSAVVTLGPSDIDTWSPMYKKYKSEELSYGDLINYMVSQSDNNACNWLINFVGGI -QNVNAFIKDLGIDQIQLIETEKSMEQDIRKSYNNWSTPLSVVQLLRKVYTEKVLSDEQFA -FLEKAMLASVSGKDKFRAGLPKEIEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD -SKESDAANAKIMADIAKKLYEHy ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0M3AZK7_9SPHN ------------------------------------------------------------- ----------------------------LGRPLPVRTLLDMSLTLSDNEATDALVARAGGP -QAVNDWVRAIGVRNLRVDSNTRDLLAGFATDPRDTATPRAMDDLLVAIRTGKALKPQSTA -MLLSIMERCRTGKDRLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRLFAITVFVMK -DYKGHQMRDRIMAEAARAAYDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A4P8WG27_KLEPN ------------------------------------------------------------- ---------------------------------QCRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. 519 TaxID=2302937 RepID=UPI0013D7B692 -hdSLRNQILSIIKGKNATVGVAVN-FDGKSQL-TINDNQKYPMMSVYKLHVAMALLDYME -KNNLSMNTEIHIKKEDLLPYSPLRDKHPEGNIPISELLKYTVSQSDNNTCDILFDYIGGP -ETVETYIKGLGIENIAICCNEKAMTENPDAVYTNWTTPSEAIKLVELFRAKNLFSPEYND -YLKTILIETTTGPNKIKGLLPEHLTVGHKTGNSSRNADNDVGFVTLPNGSGYSVAIFIKD -SKENDETNAQIISRISRVIFENy ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter rigui TaxID=1708790 RepID=UPI000F7EAB95 -----DATIARIADGSAGRIGVYAVDLASGREV-SVLGDQRFPMASTSKIAIAATFMEGVE -RGRFTLTSEFPLMVPVASKFSSAKAPVVPGKYKAVDLIEMMITRSNNQATDALLAAVGGT -SVVNDWARRNGIANFNLTRDIATLVRARTVDIRDSATPEAMVRLLTGLYQGKFLAESSRK -VILGAMGRCRTGTHRMRAMLPDDARVAHKTGTLSN-TASDIGIINTPDGRAIAVAIYVTG -QG-SREARDAKIASIARALYDGy ->[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia NIES-25 TaxID=1091006 RepID=A0A1Z4L9V3_NOSLI ----LKNTVQNLATSNNLTPGVFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQEAIAGGSGNLQKAPGTQYAALEVATKMITISDNTATNMLITRLGGI -DALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR -PNND-PRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=A0A0N0IYK7_9FLAO ---TLTQKIENIISGKKADVGVAVIGIQKNDKV-QINGKKLYPMLSTFKFPIALTTLHQVE -KGRLKLDQKLFIKKEELLEWSPFRDEHPEGNITLEEALRWMMCYSDNNLTDVIIRLIGGT -EPVQKLIGG----DFIIKNDEEGMHKDWDSQFINKITPDKAADLLEKFYQGKILNPAHTQ -WLYNAMLNNQTGLKRLKGKLPANVKVAHRSGTSFTGAVNSYGIIELPHNRKIVVAVFVHD -TYESFDNAEAIIADISRTAYDHy ->[subseq from] class A beta-lactamase n=1 Tax=Bacillus cereus TaxID=1396 RepID=UPI000B455F34 ---TVNHSFAKLEKEFDAKLGIYALDTDTNQTV-TYQSNERFAYASTHKALAVGVLLQKKS ---IEDLNQRILYTREDLVNYNPITEKYVDTGMTLKELADASLRYSDNTAQNLILKQLGGP -SEFKKSLREIGDTVTNPERFEPELNEVHPGDTHDTSTPKALATSLQAFALGDVLSIEKRN -LLIDWMKRNTT------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Novosphingobium sp. 12-64-8 TaxID=1970404 RepID=A0A257W248_9SPHN ---AIQQQVEAIVAQGRGRIGVAAMDLDGGGMV-LINGDQPFPMASCAKIAIAATYLDGVE -QGRLRLDQSFPMMMPVAQPRTSVAPVRAGTIMAAQNLMELSITRSDNHATDGLIAAVGGI -ATVNSWLTRNGIAGQRLDHTMATLVRATTIDTRTSSTPRAMIALLSAIDRGNALSPQSRA -VLLDTMTRTSTGRNRIRAGLPEGTLLAHKTGTLA-GVTDDVGIVRLPDGRHLAIAIFVTG -PEG-HTAHAGIISQVARVLYDGy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A6A1JVL5_9BACE ---SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLKIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNRSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECTTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Nostoc linckia TaxID=92942 RepID=UPI000BBC2846 ----LKNTVQNLATSNNLTPGVFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQEAIAGGSGNLQKAPGTQYAALEVATKMITISDNTATNMLITRLGGI -DALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR -PNND-PRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. TaxID=1874826 RepID=A0A3D1P461_9SPHN ---NFEAQLYSAADASNGRIGVAMIDLTSGKTT-AVLGDTPFPMASTSKIAIAATFLDGVD -KGRWSLDDQFPLMIPVKSAFSGDKAPVRAGRYTARELIELSLIHSSNPATDALLAAVGGP -GSVNRWIRTTGIDGMRIDRDIATLVRATTVDLRDSATPVAMAQLLSGLFQGRWLSSRSRA -FLLSTMERCQTGKRRMRSLLPGDARVAHKTGTLNN-TASDVGIIQAPDGHAYAVAIYVTG -QGG-HAGRDARIASIARTIY--- ->[subseq from] Beta-lactamase n=1 Tax=Legionella sp. km488 TaxID=2184757 RepID=A0A317U8N9_9GAMM ---ELIKKLRAIEKNSNTVMGLTAIYIEKNKII-EHNSSERFFMASTIKLPIAMAFLHRVD -EKKDSLDRVIKMDSRNSVPGSGALHYLFEKKISLKQILMYTLKNSDNSASDALLQAASGP -KYVAKRMSALGFKNTYINRSIMEMFLRFQKDIRDTTTPDDMAKLLVKLYKKQALSESSTD -LLMKIMEQCRTGRSRIKGLLPPNVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis terrae subsp. terrae NBRC 15098 TaxID=1219058 RepID=A0A142VW12_9SPHN ----LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD -QGKLSLDRRVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ -YLMSVMSRTRSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD -TSASIPARMALMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0R5RPQ8_9BACT --kELEQQIGQVLKDKKATVGVAVLANDTIVA--LHNNQIHFPLFSVFKFHVALAVLDKMD -KGHVSLDSIMEIKAAQMLPYSPLRQKFPDRDISLGELLKYSISLSDNNACDVLIDYVGGI -DKVNSYIKSLGLKDFNLAANEDLMHRDVATQCQNWSTLEAVVRLLNIADKQTLFAAGYKD -FLWQILKETSTGTDKLKGELPPDVIVGHKTGSSDKTADNDAGFIILPDGRKYYITVLVME -SQETDRENAAIIARISKIVYD-- ->[subseq from] Beta-lactamase family protein n=1 Tax=Bosea sp. RAC05 TaxID=1842539 RepID=A0A1B3NLV6_9BRAD ---RLSREIVAIEREAKGRLGVALLDLKDRSLW-SHRGGERFPMQSVFKWPLAIAALQAVE -AGRLWLDQPITIRRREFSLHSPLAKAFKGEAYPVRELIALAAGESDNTAADILMREIGGP -QAVTAMLKAGGITGISVDRYERQFQPLALRDSRDSATPEASVAFVEAQAKGNWLREPAHS -ALIDITLETKSGPDRIRAGLPQGARFAHKTVAGLNHATNDIGLVTLPNGRVFAIAVYLAG -STADAKQREAAHAAVARLAVA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingopyxis terrae TaxID=33052 RepID=A0A1Y6FQE3_9SPHN ----LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD -QGKLSLDRQVDIGPNDLTLHQPLAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ -YLMGVMSRTHSGPKRLKAGLPSGWEFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD -TSASIPARMALMQAVSGAVAE-- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000C6E4098 ---ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNAKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGIIAQVSKIVWDA- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Flavobacterium frigidarium TaxID=99286 RepID=UPI0009FEA965 ----LEKEINQIIANKKADVGVAILGIEDNFSL-QINGNKQYPLLSVFKFHLALAVLDKVD -KGIFTLDQKITVKERDLLEWSPFLKKYGKRDITMREALQWTISHSDNNICDVLIAKIGGI -NAINEFLNS---PHLILKNNEKQMHESWDAEFVNTTTPNYTAKLLKDFFENKIISNQATH -FLYKTMVETSVGLKRIKGQLPTNTEVAHRTGSSSTGAINDIGIVQIPNGKHVVVVVFVHN -TTEEFAVGEQIIAAISKVTYNAf ->[subseq from] Beta-lactamase n=1 Tax=uncultured Dysgonomonas sp. TaxID=206096 RepID=A0A212JKL1_9BACT ----LRNDIAKIIGGKRATVGVALI-VDGKDTL-TVNNEFHYPTQSTYKFHLALAVLDYLD -KNNLSLNHKIFIPKAELLPHSPLRDDYPDGNLSISEILKYTVSLSDNNGCDILFRFVGGP -SAVDQYIRSLGFTDFAIAATEEEMHGPWEVQYTNWSTPLTAARVLEKFRTGNILPQHFHD -FLWNAMVDTPTGPKKIRGLLPPGTIVAHKTGASFNAAENDIAIIRLPDGRYYSLTVFVAD -SMEDEATNMRIIAEISKAVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWC2_64_44 TaxID=1797935 RepID=A0A1F9TGA9_9BACT -------GLEKHSRSYRGRVGIYIKDLETGKTW-DYNSERQFPSASLIKVPIMAAVFEKIK -AGSLSLDTQIRLTRGGRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATKMLIDTV-GM -DYLSASFRALGLERTNITPEGMSLSSR-PVRRENYTTAREMGSLMERIYAGELVSREASE -FMLDVLKHTKS-RTRLRKGLPLGWEIGHKTGLLRR-NCHDVGIVFSPRGD-FVIAVLTSE -AP-NYTVAKNFIAKVAKLTYQYy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SCN 68-10 TaxID=1660098 RepID=A0A1D2RMZ9_9SPHN ----FEQRIAEIANPARGRIGVAAVDLTTGEEI-MVLGDQLFPMASTSKVAVAATYLDMVD -RGQFTLTSEFPLLLPVASASSPKAPVRPGNYMTAIDLIEIMITRSSNPATDALLAAVGGP -GNVNAWMRRHGFSDFSINRDIATLVRATRIDPRDAATPRTMVKFLSALYRGEFLQPQSRQ -VLLGALSRTVTGKRRIPAMMPVGTRVSHKTGSLNN-TSSDIGIIECPDGRVIAVAIYVTG -QG-TRAAREDKIAEISRALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. AAP60 TaxID=1523423 RepID=A0A0N0JQ15_9SPHN ----FEQRIAELANPAQGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAAAYLEMVE -QGRYSLTSEFPLMLPVASAYSSAKAPVRAGQMPAIDLIEIMITRSSNPATDALLAAVGGP -ANVNSWMRRQGIHDFSINRDIATLVRANHIDTRDAATPRAMAQLLAGLYRGEYLSDQSRS -VILSAMSRTVTGKRRIPAHIPMEARVSHKTGSLNN-TSSDVGLIECPDGRTIAVAIYVTG -QG-TRAAREARIAAIARALYDGf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E40554 ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNAVS------------------ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. StRB126 TaxID=878220 RepID=A0A077KLI7_9FLAO --pDLTKTLQSIISNKKSDIGISIIGPYKNKIT-QINGNKLYPMLSTVKFPIALTVLHKIE -KGELSLEQKLFIKKEELLEWSPFKKEYPEGNISLEEAMKWMVSYSDNNLTDILLRLIGGP -EAVQKFINNKG---VIIQNNEEDMHKDWKSQFVNKITPNEAIKLLEAFYTQKILNKEHTK -WLYTAMLNNATGTKRLKGKLPKEVKVAHRTGTSFTGAVNDYGIIELSDKKRIYIAVFVHD -TYETFENSEAIIADIAKATYDYy ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura darangshiensis TaxID=705336 RepID=A0A4R5B021_9ACTN -------------GRLGGTLGVVAHDLGTGERA-AAGADRRFAAASVIKLPILLAVLAEAE -AGGRSLDDRLAAPPDARVGGSGVVKDLADAAFSVRDLLTLMIIVSDNTATNLLIGMV-GM -DAVNAWCARHGLHGTVLARVMMDAAA-RERGEENLTTPADIAALLTGLVRGELLGERATA -RALDVLSRQQL-NDRLPRHLPAGVTLAHKTGELA-GVCHDAGIVLPGDRAPIVVVAMTEG -IE-NEHDAAALISDTGRALYA-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium nakagawai TaxID=1241982 RepID=A0A3N2F748_9FLAO ---QLKKTLESIITNKKADIGVAVLATDSKEIV-EINGNKLFPMLSTFKFHIALAILNKVE -KGDLSLQQKIYIKKEELLEYSPFKEKYPEGNLTLEECIKWMVAQSDNNLTDILLRLIGGP -EYVERFLNS---KDVIIKNDEEGMHKDWDSQFINKTTPNETIRLLGQFYNGKILNKELTK -WLYTTMLGNVSGAKRLKGHLPKEVKTAHRTGTSFTGAINDFGIIELSDKKRIYIAVFVHD -TYETFENSEAIIAAIAKAAYDHy ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8CRG1_9BACL ----WQQAIDEVLREARGEFGVAVTHLESGMTA-GHQADQLFQMASVFKIPIIATLMRDVE -AGKIRLDQRIPLRYEERVPGSGVLQELDSGALTVKDLAMLMTIVSDNYATDMVINLV-GL -ENIEAHMRELGLESIHLPQTCWQLLNAAPTTENNVATPADLNRLLTMVAKKEILSAASCD -LILDILRRQQY-NSRLPLLLPPGTKVAHKTGTVN-GVVNDAGIIYLPEGGSIAISVLSRK -VE-EKQEAERTIAKVARAVYDQ- ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium indologenes TaxID=253 RepID=UPI0007869DC8 ---TLTQKIENIISGKKADVGVAVIGIQKNDKV-QINGKKLYPMLSTFKFPIALTTLHQVE -KGRLKLDQKLFIKKEELLEWSPFRDEHPEGNITLEEALRWMMCYSDNNLTDVIIRLIGGT -EPVQKLIGG----DFIIKNDEEGMHKDWDSQFINKITPDKAADLLEKFYQGKILNPAHTQ -WLYNAMLNNQTGLKRLKGKLPANVKVAHRSGTSFTGAVNSYGIIELPHNRKIVVAVFVHD -TYESFDNAEAIIADISRTAYDHy ->[subseq from] serine hydrolase n=1 Tax=Moorea producens TaxID=1155739 RepID=UPI0010562789 ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVLLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT -DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQVYDYf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00053108D9 ---ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGIIAQVSKIVWDA- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H071 TaxID=1759078 RepID=A0A0W1GS49_9SPHN ----LSDRIYALWRAYPGRVGIAVQRIDGEWAI-AQRGPDLFPQQSVSKLWVAMTVLDAVD -NGRLSLDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -EAVRAFLRKKDLGSIRFGPGERLLQANYLANPVDGASPSAIASGLTRLARGTLLSPESTD -YLLGVMSRTKSGPKRLKAGLPAGWQFVHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS -TASPIPARMQLMQAVSGAVAE-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C5TVV5_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQAVALADYMD -KKKLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD -FIYQTMVECQTGQDRLVALLDKGITVGHKTGTGDFNGCNDIGFILLPNGHAYSIAVFVKD -SAESSLENSKIIADISRIVYKY- ->[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / NCTC 11153) TaxID=411476 RepID=A7M5B8_BACO1 --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTI-TVNNDIHYPLMSVFKFHQALALADYMG -KQGQSLETRLAIKKSDLKPYSPLRDKYPQGGMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLDKKITVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZ45_9BACT ----------SLLNGKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI0009B8EB74 ------KSFDQIEQDNDTIVGVYGVNTANGKVV-QHRSGERFAFASTYKAISSGILLQNRP ---TSELNKKIAISKDDIVAYSPVTEKYIGKQMTLKALIKASMLQSDNTANNKVIEEIDGI -KEFQQALIHRGDHISNPQRLEPDLNLYDPQSTDDTTTPKRAATTFNHLLQSENMSKANLE -LLKHTMIHNETGGTLIKAAVSKDDVVGDKSGQGTYGSRNDLAFIYPKKQKPIILAIYTKK -SDKDAKPDDKVIQTAAETAIK-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingopyxis sp. MWB1 TaxID=1537715 RepID=UPI000519F88A ----LEDRLFQLWRTFPGKTGVAVQRIDGEWAL-AQRGDDLFPQQSVSKLWVALAALDAID -QGRLSFDRSVRIGPDDLTLYQPLAARVRAEGMTVRELIETAITRSDNTANDKLLWTIGGP -DTVRSFIRKNDLGAIRFGPGERLLQSRYLADPVDGASPAAIAAALTRLARGELLSAESTS -YLLDVMSRTRSGPQRLKAGLPPGWKFGHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGN -TTASVPERMSLMQAVSGAVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides finegoldii TaxID=338188 RepID=A0A174G8M5_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIQYPLMSVFKFHQAVALADYMD -KKRLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKD -FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLENSKIIADISRIVYKY- ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis 502 TaxID=1355388 RepID=T0NFH1_9FLAO ---ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI00099A3859 ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNKVD -RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGISKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides xylanisolvens XB1A TaxID=657309 RepID=D6D2E6_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKN -SEENNQVNSKIIANISRIVYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Parabacteroides gordonii MS-1 = DSM 23371 TaxID=1203610 RepID=A0A0F5IVP1_9BACT --kELEKQLQEAIANKKAQVGIAII-INGKDTV-TINNNCRYPMMSVFKLHQALAVADYCQ -KNGISLDTPVYIRQADLKPYSPLRDKYPEGDLSIKELLEYTLLLSDNNACDILFAQAGDT -KSTDNYIRSLGLRDFSIKVTEDEMHQNESTCYENWSTPLETAKLIELLVTKELFNKESQE -FIKRTMISCETGKDRLPLPLMTNAIIGHKTGTGDRNGTNDVGFVYLPNRQRYTIAVFIKD -SEESEKATSEIIADISRIVYQY- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. 1_F178 TaxID=2258962 RepID=A0A3D9C9N5_9FLAO ---QLKKTLESIITNKKADVGVAVLATDSKEIV-EINGNKLFPMLSTFKFHIALAILNKVE -KGDLSLQQKIYIKKEELLDYSPFKEKYPEGNLTLEECIKWMVAQSDNNLTDILLRLIGGP -EYVERFLNS---KDVIIKNDEEGMHKDWDSQFINKTTPNETIRLLGKFYNGKILNKELTK -WLYTTMLGNVSGAKRLKGHLPKEVKTAHRTGTSFTGAINDFGIIELSDKKRIYITVFVHD -TYETFENSEAIIAAIAKAAYDHy ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. Root1497 TaxID=1736474 RepID=A0A0Q7Z6X9_9SPHN ----LDDRIFQIWKAFPGKTGIAVQRIDGEWTL-AQRGAELFPQQSVSKFWVTLTVLDAVD -NGRLSLDQKVRIGPEDLTVHQPIAARVQSQGMTVRDLIETAITHSDNTANDSLLRTVGGP -DAIRRFIDKKDLGAIRFGPGERLLQAAYRANPPDGASPVAIAGALTRLARGTLLSSESTQ -YMLGVMSRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVMMGE -ATSPIPARMATMQAVSRAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A412IKK9_9BACE --qEIEQQIDSLLKEKKATVGVAVLA--NGETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQENDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A349TB77_9SPHN --tSLERRIAQLADGDKGRIGIAAIDLATGREV-SVLGNQLFPMASTSKIAVAAAYLEIVE -QGKYSLTSEFPLLIPVRSASSPAAPVRKGEYMAAVDLIEIMITRSSNPATDALLAAVGGP -AKVNDWVKRQGIEEFSIDRDIATLVRAYHIDDRDAATPRAMAELLQGLYQGKFLSAESRE -VILGAMSRTVTGKRRIPALMPEEAAVSHKTGSLRN-TSSDIGIIEAADGRAIAVAIYVTG -QG-SRRNREDKIAMIARAVYDGf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. GV010 TaxID=2135477 RepID=A0A2V5BA41_9SPHN ----FEARLAAVANASHGRIGVAAVDLSNGKGI-SVMGDQPFPLASTGKVAIVATFLDGVD -QGRFRLTDRFPIMMPTYSRGSGPAPQRAGALYSATQLIDMAIIHSNNHATDALLAAIGGP -GAVDRWLRKSGIGGIRIDRDIATLVRATTIDLRDSTTPQAMATMLAGLYQGQWLSPNSKA -VLLSAMGRCATGSHRIRGLLPSDAIVGHKTGTLNN-TSSDVGIIRTADGRNIAIAIYVTG -QG-SKPGRDSRIASIARTVYEGy ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-14 TaxID=2013660 RepID=A0A2N3DAZ3_9PROT ---SFEQRIAELANAEQGRIGVAAIDLATGEEI-MVLGDQLFPLASTSKIAIGAAYLEMVE -QGRYSLTSEFPLMMAVRSASSPKAPVREGQYMPAIDLIEIMITRSSNPATDAMLAAIGGP -AVVNNWMRRQGINDFSINRDIATLVRATHIDPRDAATPRAMARLLAGLYRGDFLSDQSRQ -VLLGAMSRTITGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG -QG-TRLAREQRIAAIARALYDGf ->[subseq from] CME family class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A1A6CIU4_ELIMR -htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNIPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKDIKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0003F4BFD5 ---ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase n=2 Tax=Novosphingobium sp. AP12 TaxID=1144305 RepID=J2GAY8_9SPHN ------QQLAAVANASQGRIGVAAMDLSSGRMV-DVLGNQRFPMASTSKIAIAATFLEGVD -KGKWSLSSEFPLMVPVGSASSAIAPVRAGEYMTASRLIELMITRSNNYATDALLKVVGGP -KAVNAWVERAGIDDWHIDRDIATLVRARVVDNRDSATPYAMVKLLSGIYQGKWLSPSSRG -VIMGAMSRCVTGKRRIAAGLPADASISHKTGSLNN-TSSDVGIIQTPDGRVFAVAIYVTG -QG-GRPGREARIASIARTIYNGy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium CFH 75059 TaxID=2528174 RepID=A0A4R0NSX5_9SPHN ---DLQQRVAALAEPSRGRIGVMAVDLSTGQEV-AVLADQRFPMASTSKIAVAATFLEGVE -QGRWTLSSEFPLLRQSARFSSAVAPVTQGRYMPAIDLIEIMIARSSNPATDALLAAVGGP -GVVSNWMRRNGITEFSLDRDIATLVRAIHVDVRDSATPRAMVTFLRGLHEGHYLSPTSRQ -IILGAMSRTVTGQRRIRALMPMNAQVAHKTGSLNN-TSSDVGIVTLPDGRAVAMAIYVTG -QG-TRLEREAKIASIARVLYDGf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI000999187B ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. AF18-52 TaxID=2292242 RepID=A0A3R6RPG9_9BACT --eQLKADIQEIIKDKKARIGVGII-LNGKDTV-TVNNEDRYPMMSVFKFHQALAVLNYLQ -QNNLPLDTQIRMEKEDIIEYSPLRDKYPQGNLPISELLKYTIQLSDNIACDVLFKYIGGP -SVADKYIRSLGLQQFSIVITEDDMHLDLSACYLNWSTPLEAARLLDILLTRSLFKEEYQE -FIKNIMIECETGKDRLPQLLKTKAVIGHKTGTSDKGGTNDIGFVLLPDGSRYTVAVFIKD -SNESMETNAKIIASISDVIYKY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis witflariensis TaxID=173675 RepID=A0A246JUN6_9SPHN ----LNDRITQLWKAFPGKTGIAVQRIDGEWAL-SQRGEDLFPQQSVSKFWVALSILDAVD -QGRIRLDQPVRIGREDLTLYQPLAARVQAEGMSVRELIETAITHSDNTANDSLLRTVGGP -EAVRRFISKKDLGAIRFGPGERLLQSAYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLLDVMSRTRSGPRRLKAGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS -TTSPIPARMALMQAVSGAVAE-- ->[subseq from] Serine hydrolase n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A351AFF0_9BACT ---ATEAQLAAIEARSQGKLGAAVV-TAQGAHY--LHRDGKFSLQSVMKLMVAMAAVEQVD -RGQWRLDQSFEFKRSDLSLHQPITQRLGRRAITLDECIELMVTESCSGAAEFIIRRLGGP -QAVNAFLVKHDIQGMRIDRQERDLQTRYLADPRDTTTPAAMAKLLQKLLKGQLFSPKSTR -YLLGVMERTATGQDRLRAGVPKGWTLGHKTGTSSAGATNDVGIARNKAGEWVILVALLRE -STLAPRDRDRILADVARA----- ->[subseq from] Beta-lactamase n=1 Tax=Legionella steigerwaltii TaxID=460 RepID=A0A378LCB4_9GAMM ---ELIKKLNAIEKKSNTIMGVTAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDSRNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -KYVAQRMSALGFKNIFINRSIMEMFVRFEKDTRDTTTPNDMAKLLVKLYKKQALSESSTN -LLMKIMEQCRTGRSRIKGLLPPHVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis R26 TaxID=1246994 RepID=A0A290NA07_9FLAO ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. Chol11 TaxID=1385763 RepID=UPI000BE2C306 ----LLGEFSRFASLSDGTVGIAVRDLRSGETL-ELNGDTLFPMASTYKVAVAGKILSLAD -AGMLRFDEKLP---------------RLGTAMPVTALLDLMLTRSDNEATDALVARAGGP -QAVNGWLQSLGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSTIQHGKALKRDSTA -MLLGIMARCKTGKARLVGMLPPGTPVAHKTGTLN-GLGNDTGIITLPDGRPIAISVFVMK -DHRGHAARDRIMAEVARAAYDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3E5Q7_9FLAO ---ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEDVNCGIIAQVSKIVWDA- ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3DUB6_9FLAO ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEDMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. HME9302 TaxID=2161824 RepID=A0A369Q7T2_9SPHN --tALEQRIAQLADGSAGRIGVYAIDLASGEEV-SIMGDQRFPMASTSKVAIAATFLAGVD -AGRWSLTSEYPLLRPVRSAYSSARAPVRNGNISARKHLDLMISKSCNSCTDALLRVVGGP -EAVNAWMRGAGISEFELTRDIATLVRASMVDRRDSATPRAMGQLLAGIYQGRLLSANSRS -VLINAMKKTTTGKNRMVAALPAYANVAHKTGTLNR-TASDIGYFDTTDGRTIAVAIYVTG -QSAARSKRDRRIADISRALYEGf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0J7XZT9_9SPHN ---KLLGEFARFAALSDGSVGIGVRDLQTGETQ-ALNGDTLFPMASAYKIAVAGRIFALVD -AGQARLDEQLALDPALASEGIAWMFSRPGATLSIDRLLELMLQKSDNNATDVLVARAGGP -QAITGFVNKLGVTGLRVDSDTAHLLYAFAAELQDTSTPAAMLDLIAAYESGRALSAASTQ -RLFTIMANCETGKKRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAIAVFVMK -DSKGHVARDRIIAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. TH158 TaxID=2067455 RepID=A0A2N4X609_9SPHN ----FEASIAALAEGSQGRIGVAALDLDSGRAV-TVLGEQAFPMASTSKIAIVATFLAGVD -EGRFKLYDQYPLLVPVPSKKFSSAQAPVRQGMSALSLIEATITRSDNQATDALLAAVGGP -HAVTRWVHSTGITDFRIDRTIATLVRAVSIDKRDSVTPLGMVRLLSGIYRREWLSPMSSD -VLLGAMSRTVTGKHRIRGLLPQGTQVAHKTGTLSN-TASDVGFIKTPDGRNLAVAIYVTG -QG-GKPQRDARIAAIARALYDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0D5CA65_ECOLX --------------------------------------------------MAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGS---------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. XM-24bin4 TaxID=2133952 RepID=A0A316JWK4_9SPHN ---SFERRIAQLADGSRGRIGVAAINLNTGEEI-AVLGDQLFPLASTSKIAVAAAYLELVE -QGRYSLTSEFPLLIPVRSASSRAAPVREG-NMPASELIEIMISRSSNPATDALLRVVGGP -AAVNDWMRRQGIKEFSINRDIATLVRSAHIDTRDAATPKAMVELLQGLYQGKFLSAQSRQ -VILDAMAKTRTGTRRIPAEMPDYVQVMHKTGSLNN-TSSDIGILEGPNGHAIAVAIYVTG -QGAR-GAREARIASIARALYDGf ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter lappiensis TaxID=354630 RepID=A0A1N7G0R8_9SPHI --qSIRQQVIKIASGIKAQVGVSAMIVETGDTV-NYHAGDKFPMQSVYKLPIAIAVLHQVE -LGRLSLNQKVKVSPAEIIPVSPIRDHYPHGVLSILELLRYNISDSDGSACDVLIRILGGC -QKINQYIHGVGIRDIAISTTEMVQVSDDWVQYRNWVKPEAMLLLLKKFYAGLLLNRSHNE -LLLNLMIKSGPGAKRLKGMLPAQAVVAHKPGSSGTRATNDVGIVTLPNNKHLLIAIFIAD -TYADTEEREGVIAQITKTAWDTw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Chryseobacterium sp. FF12 TaxID=1608584 RepID=UPI0006D85723 --aELKKEISKITLGKKATVAVSVLGIDFPFQYnNENAEKKLPMQSVFKFHIALAVLDLVD -QGKLSLDQTLFIKKSELLPWSPIREKYPDGNITLAEALKWMVAESDNNCTDIILRLIDGT -KTVQNFLDKNKIKNTQIKFNEEDCHKILNLQYQNYTTTKSANNTLKVFFDKELISKNSTD -FLYKLMVETSTGKNRLVAGIPKGTEIAHRTGTSFTEAVNNIGIVTLPNEKKYAISVFVSD -SKENFDVNEKIISDISKVVFENf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJV0_STAAU ----HAKELNDLEKKYNAHIGVYALDAKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQA--------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CDS-1 TaxID=2004404 RepID=UPI000B3C025D ---RLMAEFARFSTLTDGTVGIAVRDLGTGETL-AYNGDTLFPMASTYKVAVAAKILSLLD -AGSLSLDEPLL---------------RLGRPLPVRTLLEMSLTLSDNEATDALVARAGGP -QAVNDWVHAAGIKGLRVDSNTRDLLAGFTADPRDTATPRAMDDLLAAIRLGKLLKPQTTA -LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDTGIITLPDGRIFVISVFVMK -DYKGHEMRDRIMAEAARAAYDYf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia sp. 2-6 TaxID=2575699 RepID=A0A4P8E4T9_9FLAO -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKDIKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Beta-lactamase n=3 Tax=Sphingobium TaxID=165695 RepID=A0A1L5BR14_SPHIB ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=A0A126RIS3_9SPHN ---RLMAEFARFSTLTDGTVGIAVRDLGTGETL-AYNGDTLFPMASTYKVAVAAKILSLLD -AGSLSLDEPLL---------------RLGRPLPVRTLLEMSLTLSDNEATDALVARAGGP -QAVNDWVHAAGIKGLRVDSNTRDLLAGFTADPRDTATPRAMDDLLAAIRLGKLLKPQTTA -LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDTGIITLPDGRIFVISVFVMK -DYKGHEMRDRIMAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11367 TaxID=2055774 RepID=A0A352XAB0_9CYAN ---ALTTKIQALAAQNKLQPGVLVVDLDTGNYL-DFQSNASFPAASTIKIPILVAFFQDVD -AGKIRLNESLTMEPDAIASGSGNLQQKPGTNYTALEIVTKMIAISDNTATNMIIKKLGGA -KALNQRFHDWGLRTTVINNPLPDLEGT------NTTNPKDLATLMFRVNEGELLSLRSRD -RLLNIMQQTVN-NSLIPQGLAPGAIVAHKTGDIGS-MIGDAGLVDMPSGKRYVIAIMVKR -PHND-TSASELIRQISRAVYQSf ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga dinghuensis TaxID=1539050 RepID=A0A327WDF0_9BACT ----LRDKIAQIIAGKKADIGVSVIGFQKNDTV-QFNGNQLYPMLSTFKFPIALTVLHKVE -KGELNLEQKVLIREAELLDWSPFKDEHPKGDLTLADAMRWMLCYSDNNLTDIILRLIGGA -MPVQQFI---GSKNFIIRNDEEDMHKNWDAQFINKITPNEAAQLLDKFNKGKILNAVHTK -WLYDAMVNNQTGLKRLKGKLPANIKVAHRSGTSFTGAVNSYGIIELPNHKKIIVAVFVHD -SYETFNNTEAIIADISKAAFDYy ->[subseq from] Beta-lactamase n=1 Tax=Scytonema sp. NIES-4073 TaxID=2005464 RepID=A0A1Z4PQD3_9CYAN -----KTVVQNLAAANNLTPGVFLVDLDNGSYV-DVNGSSSFSAASTIKIPILVAFFQDVD -AGNIRLDETLTMQKEMMVGGSGDMQKAVGTQFTAMEVATKMMTVSDNTATNMLIARLGGM -EVLNQRFQSWGLTTTAIRNPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMSSRD -RILDIMRRTVR-NHLLPTGLGPGATIAHKTGDIGT-TLADAGVVDMPTSKRYIVAVMVQR -PNND-SRAEKLISSISRAAYQQf ->[subseq from] Class A beta-lactamase n=1 Tax=Empedobacter brevis TaxID=247 RepID=A0A5P2GG98_9FLAO --pELKQQIDQILLNKKADVGVSIIGSGKNDNI-QINGNKMYPMLSAVKFPIALAVLDKVQ -KGELAMNQHLFIKKEELLDWSPFKEKFPEGNITLEEALSWMVSYSDNNLTDILLRLIGGP -ETVQRYINS---KYFSIKNDEEDMHKDWESQFINRITPNEAVALLKKLDDGKLLNKTYTT -WLYTAMLNNQSGAKRLKAQLPKGVKIAHRTGTSFTGAINDYGIIELPNNQKIYIAVFVHN -TYESFPDSEKIIADISKAAFDYy ->[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9431 TaxID=1173023 RepID=UPI000419D38A ---SLKTNLQSLASANNLTPGVFVVDLDNGSYV-DINASASFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMEKEMMVGGSGDMRNKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVNQGNLISMTSRD -RILEIMRNTVR-NQLLPTGLGQGATIAHKTGDIGS-MLADAGLVDLPTGKRYIVAVMVKR -PNND-LSAEKLIGSISKATYQQf ->[subseq from] Beta-lactamase CME-1 n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=X5K7C3_9FLAO ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] serine hydrolase n=1 Tax=Leptolyngbya sp. 'hensonii' TaxID=1922337 RepID=UPI0009FABDA0 ---ALKTEVQALTAQNGLTAGVFFVDLDTGAYI-DLNGDSTFSAASMIKVPILVAFLQDVD -AGKIRLDEMLTMRPDLIGSGSGVIQYRTGTQFTALEIATKMIVISDNTATNMLIDRLGGI -AALNQRFQSWGLTGTLVYNLLPDLEGT------NVTRPKELATLMFRVSQGDLLSIRSRD -RMLDIMRRTET-DTLLPRGLDDNATISHKTGDIGS-MVGDVGVIDAPNGKRYVAVAMVKR -PHND-SRAQEMIRRISRAAYQAy ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter xinjiangensis TaxID=762261 RepID=UPI000F7ED0BB --kNLQQQINQLGRQFDGKVGIAVRDVQSGWTA-AYNGREWFPQQSVSKLWVSLTALDQVD -KGKLNLSKEVTVERKDLAVFQPIRTLVLRDGTTLDDLMERAITRSDNTANDFLLWRTGGP -HAVQDTLADKNIKGIRFGPGERLMQSDYIADPVDGATPVGMVNALARLKQGKLLSSESTE -KMLDILHETRSGPRRLKGGVPGGWKIGHKTGTGQQAGYNDVGIVTAPSGNSYAVAVLIGR -TSVPLPQRMDMMQRTVRAVVNY- ->[subseq from] Uncharacterized protein n=1 Tax=Sporolactobacillus terrae TaxID=269673 RepID=A0A5K7WVX0_9BACL ----TDQAFVQLEKKFDARIGVYAFDSGTQRTV-AYRPDDRFAYASTYKALAAGAVLQQSS ---IHQLNEVILFSKDDLVTYSPIAENRVNSGMTLGEICEAAIRYSANTAGNLLLKKLGGS -NGFEKTLNKIGDNVTKANRFETDLNEAIPGDLRDTSTASALATDLKAFSVGKAPPTHKRK -MLADWMRGNTTGDQLIRAGVPKG------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Moorea producens 3L TaxID=489825 RepID=F4XTV7_9CYAN ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVLLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT -DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQVYDYf ->[subseq from] Beta-lactamase n=3 Tax=Sphingobium TaxID=165695 RepID=A0A081SYL5_9SPHN ------------------------------------------------------------- -----------------------------DRPLPVRALIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Dyella jiangningensis TaxID=1379159 RepID=A0A023NTV7_9GAMM ---RLQQALDTAARRAPGTLGLAVLDVRSGARA-GVRADEPFPMMSVFKAPVAAALLAQVE -QGSLSLAQEVTVTRADLRDGSAVPGAQVEAGFTIERLLQGAVSESDNTAVDALLRVMRGP -SVVTAFLRAHGIDGMRIDLDEGGISDAFLADPRNRSTPAAAVEFLRKLQGGELLSPASTQ -QLLRLMAGQTL-PNRLRAGVPQGVGFADKCGTSSTQAYNDIGIMTWPDGRIVIITAFLSD -SSASALQRDTLFADLARAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura montaniterrae TaxID=1803903 RepID=UPI00124EE75B --------LVRRASRLGGTLGVVAHDLGTGERA-EVNAERRFTSASVIKIAIMATVLAEAE -AGGRSLDDRLPAPPDARVPGSGVIKDLADAAFSVRDLLTLMIIVSDNTATNLLIDLV-GR -DAVNAWCARKGLRGTVLARVMMDAAA-RERGEENVTTPADVAALLTGLVRGELLGERATA -FALDALSRQQL-NDRLPRHLPPGVTLAHKTGELA-AVCHDAGIVLAKGREPIVLVAMTEG -ID-SESEAATLIAETGRAAYT-- ->[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9339 TaxID=1174528 RepID=UPI00030F6916 ---SLKTTVQSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD -AGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYILAVMVKR -PNND-PSAEKLIGSISKAAYQQf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas jatrophae TaxID=1166337 RepID=A0A1I6KZZ1_9SPHN ----FLNSIQALGSGFAGDVGIAIRDVDEGWTV-AFNADTPMPQQSVSKLWVAITVMDAVD -RGTLSLNETVTVRRSDLTVHQPIRALIGPDGTTLHEILEMAMTRSDNTANDVLLRRVGGP -AAIRRMLADKGIARVRFGPGEPRLQARYLADPEDGATASGIADGLALLAQGRLLSPMSTA -NLLGLMRRSKTGPLRLRSGLPAGWSLAHKTGTGQSTGYNDVGLVAAPNGHRYAVAVLIAS -TRQPIPARMRLMGNVMRALVR-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. NFR15 TaxID=1566282 RepID=A0A1G5TZF8_9SPHN ---ALARSINAVARSFDGRVGVAVRSIDKGWTV-ESNGDVRLPQQSVSKLWVAMTVLDFRD -SGRLTLDDPITLTRNDLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP -SAVRAFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKGELLSPTSTA -YLISTMESSKTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD -TPRTIPQRQELMQSVVQAVVA-- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000999A808 ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIIAYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYNTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00099AB5BF ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KDNLTLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] serine hydrolase n=1 Tax=Moorea producens TaxID=1155739 RepID=UPI0010FAAC08 ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT -DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 43529 TaxID=1840705 RepID=A0A367QR98_9NOSO -----KNAVQNLATSNNLTPGVFLLDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQEAIAGGSGNLQYKAAGTYAALEVATKMITISDNTATNMLITRLGGI -DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-NSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR -PNND-PRAEKLISSISRAAYQEf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00077E88C9 -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKVLVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=C6IKY5_BACT4 ---SLENQLKQAIQGKKAEIGIAVI-IDGKDTV-TVNNETHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI000660DC08 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKDVTIGHKTGTGDRNACNDIGFILLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=3 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI000B3630ED ---ELLEKINTITKDKKATVAVSVLGIENEFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGLFLSKRSTF -FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLSNGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum TaxID=46429 RepID=A0A081RGG0_SPHCR ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGKVLKPQTTA -LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DYRGHEMRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas vesicularis TaxID=41276 RepID=A0A2X1BCA7_BREVE --------LSDLETRNGGRLGFVVQDAATGRKL-VWRGDERFVYCSTFKMYLAAATLLRVQ -LGQERLDRRIPITAADMINHAPVTEPAVGASLTVEQLMKGAVEVSDNPAANLLLKAMGGP -SAMQTFYRSIGDDSTRSDRVEPEMNRL--DGDKDTILPNQSVANLQRLFLDPALTAASRA -LLLQWMTDTPTGQNRLRAGTPADWRVAHKTGTGAMG------------------------ ------------------------ ->[subseq from] Beta-lactamase BlaZ-like protein n=2 Tax=Macrococcus canis TaxID=1855823 RepID=A0A0D6DR74_9STAP ---KINEDIKVIENKYNIQAGVYVNDLTDKQKL-SYNEERLFPYASTFKVINSALLIEKLG ---MNNLDKEVKVSERDIVLYSPIIEKYKNKNVSLKMLIEAALLYSDNTANNLIIEELGGL -KEVEKRLSALGINGANVNRKEVALNFYDPKKNEDTISAKNMSKVLTKMLTGDVLEYKEQI -FLIDLMKKNKTGTTLIKKGMDKKFIVGDKSGQGNYGVRNDIAVVYKKQSKPIIVVVFTKA -KNEKQKPSDTPIVEISKVI---- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A2W5L4V7_SPHMC ----LSDRIAQLWRGFPGKTGIAVQRIDGEWSL-AERGDDLFPQQSVSKLWVVMTVLDAVD -DGRLRLDQSVRIGTEDLTLHQPMAPRVRAAGMTVRELIEAAVTGSDNTANDSLLRTVGGP -EAVRRFISKNDLGSIRFGPGERLLQSRYLANPVDGASPAAIGRALTRLARGTLLSPESTQ -YLMGVLQRTKSGPNRLKAGLPSGWTFGHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLAD -TTATVPQRMALMQAVSGAVAE-- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia bruuniana TaxID=1756149 RepID=UPI0011B6C567 -htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTRTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIITLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A415M2E0_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIAELLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium barthaii TaxID=1054037 RepID=A0A4R6FGS4_9SPHN ------------------------------------------------------------- -----------------------------GRPVPVRTLLEMSLTLSDNEATDALVARAGGP -QAVNDWVHAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLGAIRQGRVLRPQTSA -LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDTGIVTLPDGRMFVISVFVMK -DHRGHEMRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis NUHP1 TaxID=1338011 RepID=A0A077EHW5_9FLAO -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Penicillin-binding protein n=1 Tax=Nostoc linckia z16 TaxID=1628751 RepID=A0A2C6VYB3_NOSLI -----KNAVQNLASNNSLTPGVFLVDLDTGNYV-DINASTTFPAASTIKIPILIAFFEDVD -RGKIRLDEMLTMQQDMIAGGSGNMQYQAAGTYAALEVATKMITISDNTATNMLITRLGGI -DALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPKELGNLMAIISQGNLISMPSRD -LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIVVPTGKRYVAAVMVKR -PNND-PRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis NUHP1 TaxID=1338011 RepID=A0A077EDL2_9FLAO ----LKKTLESIISGKRATVGISIMGPDTKDVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDESEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Legionella drancourtii LLAP12 TaxID=658187 RepID=G9EPM0_9GAMM ---ELAKKIAAIEKKSNTIMGVTAIYIEQDKVV-THNSTQRFFMASTIKLPIALAFLHRVD -EKKDSLTRVIKLDAKNSVPGSGSLYHLFEKKMSLQQILKYMLINSDNSASDTILQAANGP -KSVAKRMGALGFKNISINRSILEILLRFENDMRDTTTPEDMAKLLVKVYKKEALSEASTD -LLLNIMAGCRTGRSRIKGLLPAHVKVAHKTGTWAFRFASDVGIITLPNNGHIAIAVYVKS -QAASDYSRSRAIALASRAIYDHf ->[subseq from] Class A beta-lactamase n=2 Tax=Elizabethkingia TaxID=308865 RepID=A0A5E8CZZ7_9FLAO -htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTRTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIITLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000937ED63 ---SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVFKFHIALAVLNQAD -KGNLTLDQKILVKKSDLHEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT -QAVQKFVNSKGIKNIQIKHNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD -FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN -STESEEINYSIIAQVSKAVFDY- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5396F ------------------------------------------------------------- --------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLYSWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter sp. Z80 TaxID=2304575 RepID=UPI00137A2585 ---TLQNQIKTLIRTHRAKVGVAIR-FGDKETI-ICNDSTRYAMMSTFKFPLALAVLSKLD -KKQLPLETEIYVTPSDLHPYSPLRDTRPEGSISISELLRYTVTLSDNNACDILIHYLGSP -AAIQDYLTRTGISGITIVATENTMHQQ-ENPYLNHCRPSAMTELLEKFLSKTLLSAPYQN -FLEKLMLATSTGADKLKGLLPPGTPVGHKTGSSDRNGDNDVGFIRLPDGRYFTIAVFIMD -SAEDDKANALLIARIARSAYEHy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A1B1S661_KLEPN ------------------------MDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVIEKHLADGMTVGELCSAAITMSDNSAANLLLITVRSP -ARLTAFLTQIGNNFTRLDRWKTKLNEAIPGNALHTTTPVSMTATLPKLLTCQRLISRSQR -PLLQCMVDDPVAGTLILSVLPAGWFISDKTGASKRAARGIVS------------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium amiense TaxID=135719 RepID=A0A494VXK2_9SPHN ---KLLAEFARFAALSDGSVGIGVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFSLID -AGDLRIDDPLALDPALASEGIAWMFSRPGATLSVQRLLELMLTKSDNNATDVLVARAGGP -QAITAFVTKLGVRGLEVDSDTAHLLYDFAIDPRDTSTPTAMLDLLTAYESGKALSAGSTQ -RLFTIMGHCETGKARIPGMLPPGTAVAHKTGSMN-GIGNDVGIVQLPDGRRFAVAVFVMK -DSRGHTSRDRIIAEATRAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. 17J27-24 TaxID=2555898 RepID=A0A4Y8ZRE0_9SPHN ------------------------------------------------------------- -------------------------------GTTARALMDAMITRSDNRATDLLIGALGGP -ASVDQWLRGHGLTGIRVDRTIAQLLSARRRDVRDSSTPTAMLGLLRLLDSGTALTPQSRS -ILLDMMRRCRTGSNRIRGILPPGATVEHKTGTLS-GYTGDVGFLTTPTGRRIAVAFFARG -GE----NRPAVIATAARMIYDAf ->[subseq from] penicillin-binding protein n=1 Tax=Hassallia byssoidea TaxID=482630 RepID=UPI000585C388 ---SLKNAVQNLALASNLTPGVFLVDLNNGAYV-DVNAGASFPAASTIKVPILVAFFQDVD -AGKIRLDETLTMQQDMVAGGSGNMQKPVGTQFTALEVATKMITISDNTATNMLIAKLGGI -EALNQRFRSWGLTTTVIRNKLPDLEGT------NTTSPKELGNLLMMVNQSNLVSLQSRD -RLLDIMRRTEK-DTLLPSGLGVGATIAHKTGDIGT-MLADAGLVDMPTGKRYIAAVMIQR -PNND-ARAEKLISAISGIAYQQf ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix brevissima NIES-22 TaxID=1973478 RepID=A0A1Z4K0S2_9CYAN ----LKSAVQNLIANPNLTPGVMLVDLDTGSYV-DINSNASFPAASTIKIPILVAFFQDLD -AGKIRLDEMLTMEQQAIAGGSGNMQYKPAGTFNALEVVSKMITISDNTATNILIARLGGI -ESLNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPKELATLMAMVNQGNLVSMRSRD -RLLEIMRQTQK-DTLLPSGLGTGATIAHKTGDIGT-MLADAGLVDMPTGKRYIAAVMIQR -PNND-TRAEKLISAISRTAYQQf ->[subseq from] class A beta-lactamase n=2 Tax=Rikenellaceae TaxID=171550 RepID=UPI0009E7A2B1 ---QFESRLDEILSGHKAFVGVAVR-TPGGETI--ARNDTLLPMMSVFKFPVALAVLDRMQ -REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYMVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCGTTTGANKLKAGLPAEIVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE -SEENDATNAAIAASASRAAYEYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A657C3X3_9SPHN ---KLLGEFERFATXSDGTVGIAVRDLQTGXTQ-AIXGDTLFPMASAYKVAVAGRIFALID -AGDVRLDDQLALDPALASEGIAWMFSRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP -AAITHFVKGLGVDGLRVDSDTAHLLYAFATEIEDTSTPRAMLDLLTAYESGKALSADSTQ -RLFTIMAHCETGKGRIIGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK -DSKGHKSRDRIIAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8C2I0_9BACL ----WQQVIDEVLQEAQGEFGVAVTHLESGETA-GHQADQLFQMASVFKIPIIVTLMRDVD -AGKFRLDQRVTLRYEERVPGSGVLQELDSGALTVKDLAMLMTIVSDNYATDMLINLV-GL -ENIEAHMRELGLRNIYLPQTTWQLLNGEPTTANNVASPADLNRLLTMVAKKEILSEASCD -LILDILRRQQY-NSRLPLLLPEGTKVAHKTGTVN-GVVNDAGIIYLPDGGSIAITVLSRN -VA-EKQAAERTIAQVARAVYDQ- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. CF01-10NS TaxID=2292956 RepID=A0A3A5S8W8_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKLYSPLRDKYPQGGMSIADLLRYTLQQSDNNACDILFNYQGGP -DAVNKYIYSLGIRECAIVGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPKVYKD -FIFQTMVECQTGQDRLVALLNKKVTVGHKTGTGDQIGCNDIGFVLLPGGRTYSIAVFVKD -SEENNQANNKIIANISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. CENA543 TaxID=1869241 RepID=A0A2I8AD04_9NOSO ---TLKNAVQELAAANNLTPAVFLADLDTGGYV-DLNADNSLPAASTIKVPILIAFFQDVD -AGKIRLDEMLTIQQEMIVGGSGDFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI -EAVNQRFQSWGLTSTVIRNPLPDLSGT------NTTSPKELGNLLAMVSQGKLVTMRSRD -QILDIMRRTQR-DQLLPAGLDAGARAYHKTGDIGT-LLADAGIIDTPTGKRYIAVVMVQR -PNND-PRAEKLISSISRAAYQEf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A0P0EXG0_BACT4 ---SLENQLKQAIQGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium rosa TaxID=76978 RepID=UPI000A06F348 ----FEARLASVANAAHGRIGVAAVDLSNGKGI-SVMGDQPFPMASTVKVAIVATFLDGVD -QGKFRLTDRFPIMMPLPSRGSGPAPQREGPIYSATQLIDMTIIHSNNHATDAILAAIGGP -KAVDRWLHKAGIGGMRIDRDIATLVRATTIDLRDSTTPQAMATLLAGLYQGQWLTPGSRA -VLLSAMSRCATGTHRMRGLLPNDAIVGHKTGTLNN-TASDVGIIRTADGRNIAIAIYVTG -QG-SKPGRDSRIASIARTVYEGy ->[subseq from] Serine hydrolase n=1 Tax=Westiellopsis prolifica IICB1 TaxID=1970206 RepID=A0A4V2JNA0_9CYAN ---SLKTTVQSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD -TGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR -PNND-PSAEKLIGSISKAAYQQf ->[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=UPI0005A63967 ---------QTLAAANHLMPGIFLVDLDTGSYV-DINGAASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQQEAIAGGSGNMQKPVGTQYTALEVATKMITISDNTATNMLISKLGGM -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPRELAQLMAIVNQGTLVNMRSRD -RLLDIMRQTQR-DNLLPSGLGAGASIAHKTGDIGT-MLADTGLVDIPTGKRYIASVMVQR -PNND-PRAEKLISAISQATYQQf ->[subseq from] Serine hydrolase n=1 Tax=Mastigocladus laminosus UU774 TaxID=1594576 RepID=A0A4D9CKW3_MASLA ---SLKTTVQSLASANNLTPGVFVVDLENGSYV-DINASGSFPSASTIKIPILVAFFQDVD -AGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR -PNND-PSAEKLIGSISKAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=K9PH05_9CYAN ---------QTLAAANHLMPGIFLVDLDTGSYV-DINGAASFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQQEAIAGGSGNMQKPVGTQYTALEVATKMITISDNTATNMLISKLGGM -EALNQRFRSWGLTTTAIRNQLPDLQGT------NTTSPRELAQLMAIVNQGTLVNMRSRD -RLLDIMRQTQR-DNLLPSGLGAGASIAHKTGDIGT-MLADTGLVDIPTGKRYIASVMVQR -PNND-PRAEKLISAISQATYQQf ->[subseq from] Beta-lactamase class A n=1 Tax=Hephaestia caeni TaxID=645617 RepID=A0A397P9T2_9SPHN ----LVAAIKAIGTQFDGKVGIAVQSINQGWTV-SSNGDVKMPQQSVSKLWVALTVLDLRD -QGRLTLDDPVTVTKADLTLHQPVASLVGDTGTTVRDLQYRAITSSDNTANDRLLSYVGGP -EAVRAMIARKQLGAIRFGPGERLLQSAYVADPIDGASANAIADALARLVKGDLLSPSSTQ -WLIQTMSETRTGRARLRANLPGGWSIAHKTGTGQTAGFNDVGVLTAPDGRRYTVAVLIGD -TSRPVRERQQLIQSVAGAVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium taihuense TaxID=260085 RepID=A0A562JS65_9SPHN ---AIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNADMPFPMASTAKVAVAATFLEQVE -KGTFRLDQQFPMMIPVRETGARSAEAPLRSGMTAQSLMELMITRSHNEATDGLIRAVGGY -ENVNRWLSAKGIVGQRLDHTMATLVRARVIDVKTSSTPRAMLALLSAIDRGGALSPESRA -VLLDTMTRTTTGKNRMRAGLPEGTLVAHKTGTLA-GVTDDVGIVRLPDGRHLAVVFFVTG -PEG-HTVHAGLIARMMRTIYDGy ->[subseq from] CME-1 protein n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=Q9RAZ9_ELIME -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter litoralis TaxID=39960 RepID=A0A074MVK9_9SPHN ----FEQRIAALADGSNGRIGVAAVDLATGDQI-AVLGDQLFPMASTSKIAIAATYLDMVE -KGQFSLTSEWPLMIPIRSASSPAAPVREGKYMQAIDLIEIMITRSSNPATDALLAAVGGP -ESVNEWIRRQGINEFSINRDIATLVRASYIDPRDAATPKAMVRLLTGLYRGDFLSDTHRR -VLLGAMSRTVTGKRRIVANMPDEAVVSHKTGSLNN-TSSDIGIIEYPDGRAIAVAIYVTG -QG-SRLAREQRIAAIARALYDGf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter luteolus TaxID=295089 RepID=UPI00136B09E6 ---SFERQLAKVADGDQGRIGVSAIDLTTGYQV-SVLGDQRFPMASTSKVAIAATFLAGVD -QGRWSLTSEFPLLIPVKSGSSPRAPVREGTYLPAEQLLNLMISKSSNASTDALLRVVGGP -QAVNAWMRRAGIDDFELSRDIATLVRATRIDNRDSATPNAMAKLLAGLYQGKWLSRSSRD -VLIGAMENTTTGKRRIRSALPMSANVAHKTGTLNR-MASDIGIFETPDGRAIAIAIYVTG -QSEARRKRDERIANIARALYNGf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0004132182 -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase n=1 Tax=Fluoribacter gormanii TaxID=464 RepID=A0A377GMK8_9GAMM ---ELIKKLQAIEKNSNTVMGLTAIYIEKNKII-EHNSSQRFFMASTIKLPIAMAFLHRVD -EKKDSLDRVIKMDSSNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -KYVAKRMSALGFKNTFINRSIMEMFLRFQKDIRDTTTPDDMAKLLVKLYKKQALSESSTD -LLMKIMEQCRTGRSRIKGLLPPNVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. 65-8 TaxID=1895852 RepID=A0A1Q3UNU6_9SPHN ----LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD -QGKLSLDRQVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ -YLMGVMSRTHSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD -TSASIPARMALMQAVSGAVAE-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WGU3_9BACT ---ELSARLQKLCDRAGASIGLALMHVETGRTV-EIQGKTSLPLYSVFKLPLAIAVLKDVE -ENRLRLDQKVRVTPADVAPGSQGNAALWRKPKTVAELLELSIGRSDNTSSDKLLQLVGGP -DKVMQRMRSLGFQDIEIRSAVRELATR--QGKPNTGTASDLARLLSGLQQGQVLQPPQRT -LLLGFMERATTGLRRLRGDLPAGTIVADKTGTGEDGVTNDVGLITLPEGGHLAMAVLISG -SKLPAEAQEKLIAELAKTAYD-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A0W1II93_9SPHN ----LSDRISQLWRTFPGKTGIAVQRIDGEWSF-SERGGELFPQQSVSKLWVAMTVLDAVD -QGKLSLDRQVDIGPNDLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -EAVRRFIAKKDLGSIRFGPGERLLQSAYLANPMDGAAPAAIASALTRLARGALLSPESTQ -YLMGVMSRTHSGPKRLKAGLPSGWDFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGD -TSASIPARMALMQAVSGAVAE-- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium CCH3-A5 TaxID=1768796 RepID=UPI0009E73F1B --aKLDREIAGIERDSKGRLGVALIDLKDRTAW-SHRGSEHFPLQSVFKLPLAVAVLQAVE -AGTLRLDQPVTVTRKDLSLHSPLATRFKGERVPLRELVRLAAAESDNTAADLLTRLIGGP -QILTAMLKAGGVVGISVDRYERVFQPATLSDRRDAATPDASVAFLEAFAKGNWLRQPEHS -RLIEFAAGALTGKDRIRAGLPEGSRFAHKTGLGPNHATNDIGIVTLPNGRIFAIAVYLAG -STGAPEQREAAHAAVARLAVA-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000332C3F5 ---SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVFKFHIALAVLNQAD -KGNLTLDQKILVKKSDLHEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT -QAVQKFVNSKGIKNIQIKHNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD -FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN -STESEEINYSIIAQVSKAVFDY- ->[subseq from] CME_2 extended spectrum beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=Q9RAZ8_ELIME -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGIIAQVSKIVWDA- ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=A0A1T3D5V5_9FLAO ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Moorea producens JHB TaxID=1454205 RepID=A0A1D9G401_9CYAN ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFNLEQGKWISPQSRT -DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Nostoc commune NIES-4072 TaxID=2005467 RepID=A0A2R5FGJ0_NOSCO ---SLKSAVQNLAATNNLTPGVFLLDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGTLQRQPAGTYAALEVATKMITVSDNTATNMLIARLGGI -DALNQRFRTWGLTTTTIRNQLPDLQGT------NTTTPRELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DTLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYIASVMVQR -PNND-PRAEKLISSISSVSYQEf ->[subseq from] serine hydrolase n=1 Tax=Fortiea contorta TaxID=1892405 RepID=UPI000475D12D -----KNTVQTLAAANNLTPGVFLVDLETGAYV-DVNGAASFPAASTIKVPILVAFFQDLD -AGKIRLDEMLTMQQEAIAGGSGNMQKPPGTQYTALEVATKMITISDNTATNMLITRLGGI -EALNQRFRSWGLTNTVIRNQLPDLQGT------NTTSPRELSQLLAIVNQGNLVNMRSRD -RLLDIMRQTQR-DNLLPSGLGTGASIAHKTGDIGT-MLADTGLVDIPTGKRYIATVMVQR -PNND-PSAEKFITSISRTAYQQf ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. M24A2M TaxID=2682494 RepID=UPI0012EBB6A2 ---AFEARIASLANASQGRIGVAAMDLKTGKVV-DVLGDQRFPMASTSKIAIAATFMEGVE -QGRWSLTSEFPMMMPVRSESTAVAPVRAGEYYSAERLIELMLTRSNNYATDALLRVVGGP -RAVNEWTRRAGITDWQIDRDIATLVRAEVIDTRDSATPLAMVQLLAGLHEGKWLSDRSRA -VILGAMGRCVTGKRRIVANLPSEARVAHKTGSLFN-TSSDVGIIQTPDGRSFAVAIYVTG -QG-TRLNREARIASIARALYDGy ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter gangjinensis TaxID=1028742 RepID=UPI00136A3D9A ----FERRIAQIADGDEGRIGVAAVDLSTGQAI-SILGDQRFPMASTSKLAIAATFLEGVE -RGRWSLSSEFPLLVPVRSAYSSLKAPVRKGNLPASDLIEIMITRSSNSATDALLNVVGGP -SAVNAWMRRNGMDEFQLTRDIATLVRVAHIDERDSATPKVMVQFLTGLYQGRFLSASSRS -VIIGAMERCRTGKRRIPALLPDSANVAHKTGSLNN-TSSDIGTFITPDGRTIAVAIYVTG -QGAR-LKREARIAQIAKALYDGy ->[subseq from] Penicillin-binding protein n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2LVN1_9CYAN ----LKTVIQNLAAANNLTPGVFLVDLDNGGYV-DVNGSSSFSAASTIKIPILVAFFQDVD -AGNIRLDETLTMQKEMMVGGSGMRYKPVGTQFTAMEVATKMMTVSDNTATNMLIARLGGM -EVLNQRFQSWGLTTTAIRSPLPDLQGT------NTTSPKELGNLMAMVSKGNLVSMSSRD -RILDIMRRTVR-NHLLPTGLGPGATIAHKTGDIGT-TLADAGVVDMPTSKRYIVAVMVQR -PNND-ARAEKLIGSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Legionella drancourtii TaxID=168933 RepID=UPI00058BE755 ---ELAKKIAAIEKKSNTIMGVTAIYIEQDKVV-THNSTQRFFMASTIKLPIALAFLHRVD -EKKDSLTRVIKLDAKNSVPGSGSLYHLFEKKMSLQQILKYMLINSDNSASDTILQAANGP -KSVAKRMGALGFKNISINRSILEILLRFENDMRDTTTPEDMAKLLVKVYKKEALSEASTD -LLLNIMAGCRTGRSRIKGLLPAHVKVAHKTGTWAFRFASDVGIITLPNNGHIAIAVYVKS -QAASDYSRSRAIALASRAIYDHf ->[subseq from] Uncharacterized protein n=2 Tax=Dysgonomonas gadei TaxID=156974 RepID=F5J1N6_9BACT ----LRNDIEKIIRGKRATVGVALI-VDGKDTL-TVNNGFHYPTQSTYKFHLALAVLDYLN -KNNLSLDHKIFIRKAELLPHSPLRDDYPDGNLPVSEILKYTVSQSDNNGCDILFRFVGGT -SAVDRYIRDLGFSDFAIAATEEEMHGPWEVQYTNWSTPLTAARVLEKFRTGNILPQHFHD -FLWNAMVDTTTGPKKIKGLLPPGTIVAHKTGSSFNAAENDIAIIRLPDGRYYSLAVFVAD -SMEDEATNMRMIAEISRAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7HIF1_9NOSO -----KNAVQDLATSNNLTPGVFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDVMAGGSGNLQYKPAGTYAALEVATKMITISDNTATNMLITRLGGI -DALNQRFRSWGLTTTVIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DSLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYVAAVMVQR -PNND-PRAEKLISSISRAAYQEf ->[subseq from] serine hydrolase n=1 Tax=Fischerella muscicola TaxID=92938 RepID=UPI0002DAAFB2 ---------QSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD -AGKIRLDEMLTMEKEMMVGGSGDMRNKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILEIMRNTVR-NQLLPTGLGQGATIAHKTGDIGS-MLADAGLVDLPSGKRYIVAVMVKR -PNND-PSAEKFIGSISKAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Fluoribacter gormanii TaxID=464 RepID=UPI0010411413 ---ELIKKLQAIEKNSNTVMGLTAIYIEKNKII-EHNSSQRFFMASTIKLPIAMAFLHRVD -EKKDSLDRVIKMDSSNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -KYVAKRMSALGFKNTFINRSIMEMFLRFQKDIRDTTTPDDMAKLLVKLYKKQALSESSTA -LLMKIMEQCRTGRSRIKGLLPPNVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00136BFBAB ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDESEKIISDIGRATYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000361857C --nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE -KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT -DTVQKF---IGTKDFIIKNDEEDMHKAWDSQFINKITPNRATQLLDKFYQGKILNRVNTK -WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD -TYENFNDSEAIIADIAKTVYDYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum L-1 TaxID=690566 RepID=F6EZS5_SPHCR ------------------------------------------------------------- ------------------------------RLLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIKGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGKVLKPQTTA -LMLSIMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia TaxID=308865 RepID=UPI000999C6D5 -htSILNDINAVTKDKKATVAVSVLGIENEFQFsNTNGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A174SE91_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides finegoldii TaxID=338188 RepID=A0A642LXP6_9BACE --sQLKTLLEQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIQYPLMSVFKFHQAVALADYMD -KKRLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKN -FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLKNSKIIADISRIVYKY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000999E32C -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGIIAQVSKIVWDA- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. RIFCSPHIGHO2_01_FULL_65_24 TaxID=1802171 RepID=A0A1G3K0C1_9SPHN ----LDDRIFQIWKAFPGKTGIAVQRIDGEWAL-AQRGGELFPQQSVSKFWVTLTVLDAVD -NGRLSLDQKVRIGPEDLTVHQPIAARVQSEGLSVRELIEMAITHSDNTANDSLLRTVGGP -DAVRRFISKKDLGAIRFGPGERLLQAAYRASPPDGASPAAIAGALTRLARGTLLSPESTQ -YMLGVMSRTKSGPQRLKAGLPAGWTFLHKTGTGQTVGYNDIGIATAPDGTRYAIVVMMGE -ASSPIPARMATMQAVSRAVAE-- ->[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc flagelliforme CCNUN1 TaxID=2038116 RepID=A0A2K8SLN2_9NOSO ---SLKSAVQNLVATNNLTPGVFLLDLDTGNYV-DVNASTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGTLQRQPAGTYAALEVATKMITVSDNTATNMLIARLGGI -DALNQRFRTWGLTTTTIRNQLPDLQGT------NTTTPRELGNLMAIVSQGNLVSMTSRD -FMLDILRRTQR-DTLLPSGLGTGARVYHKTGDIGT-MLADAGLIIVPTGKRYIASVMVQR -PNND-PRAEKLISSISSVSYQEf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0004E3A5F7 -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI0009997E74 ----LKKTLESIISGKKATVGVSIMDPDTKEVT-WINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYNYy ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127SLF7_9BACT --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KKJ8_9BACT --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQENDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. AF14-59 TaxID=2292240 RepID=A0A3R6PQN9_9BACT --eQLKANIQEIIKDKKARIGVGII-LNGKDTV-TVNNEDRYPMMSVFKFHQALAVLNYLQ -QNNLPLDTQIRIEKEDIIEYSPLRDKYPQGNLPISELLKYTIQLSDNIACDVLFKYIGGP -SVADKYIRSLGLQQFSIVITEDDMHLDLSACYLNWSTPLEAARLLDILLTRSLFKEEYQE -FIKNIMIECETGKDRLPLLLKTKAVIGHKTGTSDKGGTNDIGFVLLPDGSRYTVAVFIKD -SNESMETNAKIIASISDVIYKY- ->[subseq from] Serine hydrolase n=1 Tax=Symploca sp. SIO1C4 TaxID=2607765 RepID=A0A6B3NLY9_9CYAN ---QLKAQMHAIVAQNNLQPGVFLLDLDTGAYL-DWDSRSTFAAASTIKVPILVAFFQALD -AGKVRLDETLIMESEMIATGSGDMQQQPGTQYTALEVITKMIAISDNTASNMIIARLGGA -EALNQQFRSWGLATTAIRNLLPDLEGT------NTTSPREIARLMSIVNQGQLLSLRSRD -RLLDIMRQTQN-DSLLPQGLGNGATIAHKTGNIGS-VLADVGIVDMPTGKRYLIAVMVKR -PH-DDASAQKLIRDISRTAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A4Q5R3N7_9PROT ------------------------------------------------------------- ---------------------------------SATQLLELMIVRSDNGATDLLLAALGGP -ATVQQWLWSQKITGMRVDRTIAQLLRGHLADSKDVATPVAMVALLNKLDSGDVLTPRSRT -FLFDLMRRCETGTRRIRALLPAGTMVEDKTGTLD-GVTNDVGFINMPDGRRVAIAVFARG -GR----DRQPVIAQVSRMIYDRf ->[subseq from] Uncharacterized protein n=2 Tax=Bacteroides caccae TaxID=47678 RepID=I9EQW5_9BACE ---SLETQLKEAIKDRKAEIGIAVI-IDEKDTV-TVNNDIHYPLMSVFKFHQALALADYMA -KRNQSLDTLLRIEKSDLKPYSPLRDKYPQGGMSIADLLRYTLQQSDNNTCDILFDYQGGP -DAVNRYIHSLGIRDCAIVGTETAMHEDLDLCYQNWSTPLAAAELMEIFRREPLFAQEYKD -FIYQTMVECKTGQDRLVAPLAKGVVIGHKTGTGDQIGCNDIGFVLLPDGRTYSIAVFVKD -SEESFAENSKIIADISRIVYEY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00084018A8 ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAILNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A0W8ETH8_ELIMR ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKILVKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -NTVQKLMNVNGVKNFQVKYNEEKMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A6B2F408_KLEPN ------------------------------------------------------------- --------------------------------------------DSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PEQKAESRRDILAAAAKIVTHGf ->[subseq from] Beta-lactamase TEM (Fragment) n=1 Tax=Escherichia fergusonii TaxID=564 RepID=A0A679G4T1_ESCFE ----------------GARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTCANI------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HP03_9BACT --aELEKQIAKIAESAKGKVGVAAVLLETGDSA-MLISDQRFPMQSVYKLPISMAVMDQTR -RGELDLDEKIGVTKEDMVGHSPLRDANPNGGFTIRELIRFALVESDGTASDVLMRIAGGG -PQIQNFLTQIGVKNMRVLNTEKDLALDWQKQYQNYSTPNDAIELLRWLQTSTLAEDKAND -ELVMWMEASIPGAKRFKGSLPPNTIVAHKTGTSGTAATNDIGIITLPNGKHIAIAVFVSD -SPADQDARETVIARVAKAVWDRw ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A1Y4JZ20_9BACE --qTLESKIDDFLKGKKAMVGVAVM-TGRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN -KQETPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD -FLWNTMIATSTGSNKLKGLLPSNTIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMVYDEy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AM10-21B TaxID=2292001 RepID=A0A415CLM8_9BACE --qTLESKIDNFLKGKKATVGVAVL-TDRNEIL-LYNNKMNYPLLSVFKFHVALAVLDKMN -RQETPLDHIIHVKASQLQPYSPLRQKYPNQDISLGELLQYSISLSDNNACDILIKYAGGI -GHIHQYIKKLDINDFNLSETEDSMHRNPSKAYLNWSTPYEMVQLLRIADEKELFAPVYKD -FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SSETDDENAAIIARISRMVYDE- ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A1A6CGR1_ELIMR ----LKKTLESIISGKKATVGVSIMDPDTKEVT-WINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRATYDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. Fuku2-ISO-50 TaxID=1739114 RepID=A0A102DC07_9SPHN ---------GALERRSGGRLGVMVLDSARARGF-GWRQDERFAHCSTFKLSLAAMVLAQID -AGRARGDEVVPYSVLDVLPASPVTDPVLAGQLPVFALAEAAVERSDNLAANLLLARFGGP -AALTAFWRATGDPISRLDHHEPALNRVAPGADQDTTTPAAMAATVARLLTGSVLSGESRA -RLWGWMKGAPTGLGRLRGGLPARWQGGDKTGTWTPAKINDIALALAPVGAPLAVTAYYEP -LGAVRPEDEAVLAAVMRIAAD-- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter mangrovi TaxID=1982042 RepID=UPI000BA24A29 ----LEQLVGQIADGSKGRIGVAAVDLATGEQV-SVLGDQRFPMASTSKIAIAATFMQGVE -DGRWTLTSEFPMMVPVRSESSAVAPVRPGRYYQAVDLIEMMITRSNNEAADALLKVVGGP -KAVNAWVHAHGVENFHIDRDIATLVRASHIETRDSATPKAMVKLLTDLYQGKVLSDSSRQ -VILGAMERCRTGVRRIKALLPDDAIVAHKTGSLHN-TSSDIGLVKAPNGHTIAVAIYVTG -QG-SRLARESKIAHIALTLYDGy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter longus TaxID=1044 RepID=A0A074M8S0_ERYLO ---SFEQRIAELADGSDGRIGVAAWDLATGEQI-TVLGNQLFPMASTSKIAVAAKYLEMVE -QGQYSLTTEFPLLIPVRSASSAAAPVRKGNSMAAIDLIEIMITRSSNPATDALLAAVGGP -QAVNDWMRRQGISDFSLDRDIATLVRANWIDPRDAASPKAMVRLLAGLYRGEYLSDESRR -VLLGAMSRTVTGKRRIVADMPGEARVSHKTGSLNN-TSSDIGIIESPDGRAIAVAIYVTG -QG-SRGAREARIASIARALYDGf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A5C7UFL3_9SPHN --qAIQQQVAAIAAEGRGRIGVAAMDLDGGGQI-FVNADMPFPMASTAKIAVAATFLDLVE -KGAARLDQQFPMMMPVRETGARSAEAPLRSGMTAQSLMELSITRSHNEATDGLIQAVGGY -DKVNRWLTSKGITGQRLDHTMATLVRARVIDVRTSSTPRAMLALLAAIDRGDALSPESRA -VLLDTMTRTSTGKNRIRAGLPVGTLVAHKTGTLF-GVTDDVGIVRLPDGRHLAVVFFVTG -PEG-HTAHAGLIARMMRTIYDGy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas jatrophae TaxID=1166337 RepID=UPI000B838CE1 ----FLNSIQALGSGFAGDVGIAIRDVDEGWTV-AFNADTPMPQQSVSKLWVAITVMDAVD -RGTLSLNETVTVRRSDLTVHQPIRALIGPDGTTLHEILEMAMTRSDNTANDVLLRRVGGP -AAIRRMLADKGIARVRFGPGEPRLQARYLADPEDGATASGIADGLALLAQGRLLSPMSTA -NLLGLMRRSKTGPLRLRSGLPAGWSLAHKTGTGQSTGYNDVGLVAAPNGHRYAVAVLIAS -TRQPIPARMRLMGNVMRALVR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus xylosus TaxID=1288 RepID=Q2FC38_STAXY ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDXRXXXXXXXKAXNSAILLEXVP ---YNXLNKKIHINKDDXVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRXXXEXNYXXPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDK----------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A174U7I0_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SAENNQENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SW99_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRAMGDEVTQLDRWETELNEATPGDLRDTTTPAAMVSSLHELLLGEVLSPAASD ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6SSF3_9SPHN ---KLLGEFARFAALSDGTVGIGVRDLQTGETQ-ALNGDTLFPMASAYKVAVAGRIFALID -AGKLRIDDQLALDPALASEGIAWMFSRPGATLPVQRLLELMLTKSDNNATDVLVARGGGP -QAVTAFVTGLGIKGLEVDSDTAHLLYAFVIDPRDTSTPTAMLDLLTAYDSGRALSADSTQ -RLFAIMGHCETGKARIPGMLPPGTAVAHKTGSMN-GIGNDVGVVRLPDGRRFAIAVFVMK -DSRGHTSRDRIIAEATRAAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. C100 TaxID=1207055 RepID=W1RP35_9SPHN ---KLLAEFGRFAALSDGTVGIAVRDLQTGETQ-AINGDTLFPMASAYKVAVAGRIFALID -AGDVRLDDQLALDPALASEGIAWMFNRPGASLSVQRLLELMLQKSDNNATDVLVARAGGP -QAITHFVTGLGVAGLRVDSDTAHLLYSFATEPEDTSTPKAMLDLISAYESGRALSADSTQ -RLFTIMAHCETGKGRIVGMLPPGTAVAHKTGSLN-GTGNDVGVVRLPDGRRFAVVAFVMK -DSKGHKARDRIIAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. OM08-17BH TaxID=2292285 RepID=A0A374USD6_9BACE --qTLESKIDNFLKGKKATVGVAVL-TDRNEIL-LYNNKMNYPLLSVFKFHVALAVLDKMN -RQETPLDHIIHVKASQLQPYSPLRQKYPNQDISLGELLQYSISLSDNNACDILIKYAGGI -GHIHQYIKKLDINDFNLSETEDSMHRNPSKAYLNWSTPYEMVQLLRIADEKELFAPVYKD -FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVITPDGKKYYIAVFVMN -SSETDDENAAIIARISRMVYDE- ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI0007870B6B ---DLKKTIESIISNKKADVGVSIIDPYHKERI-QINGNKLYPMLSTVKFPIALTVLNKIE -KGELSLQQKLLIKKEELLEWSPFRKEYPDGNISLEEAIKWMVSYSDNNLTDILLRLIGGP -EPVQQFINS---KDFIIRNNEEDMHKDWESQFVNKITPNETTKLLEAFNNGKILNKKHTL -WLYNAMLNNTTGTKRLKGNLPQHVKTAHRTGTSFTGAVNDFGIIEISGKKKFYIAVFIHD -TYEKFGDAEAIIADISKAAYEYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chryseobacterium sp. PMSZPI TaxID=1033900 RepID=A0A2N0XI14_9FLAO ------------------------------------NGDKPLPMLSVFKFHLASTVLDLVD -KGKYSIDQKFLIKKSDLLEWSPLREKYPNGNLPLAEIISYTVAQSDNNTCDFLLKLIGGP -QTVQQFMDSKGVKNVHIKYNEDDMHRDWKTQYGNSSSTNSIVDLLKKFYDGKLISQKSTD -LLMQIMLGTTTGTNKIVEQLPKGTPIAHKTGSSGTVAENDMGIISLPNGKHYAIAVFVSN -STETEKVNTRIVSDISKVVWDDf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00099A82E1 ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---TSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-15 TaxID=2013661 RepID=A0A2N3DL78_9PROT ---SFEQRIAELANADQGRIGVAAIDLATGEEI-MVLGDQLFPLASTSKIAIGAAYLEMVE -QGRYSLTSEFPLMMAVRSASSPKAPVREGQYMPAIDLIEIMITRSSNPATDAMLAAIGGP -AVVNDWMRRQGINDFSINRDIATLVRANHIDPRDAATPRAMVRLLAGLYRGEFLSDQSRQ -VLLGAMSRTITGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG -QG-TRLAREQRIAAIARALYDGf ->[subseq from] serine hydrolase n=1 Tax=Croceicoccus mobilis TaxID=1703339 RepID=UPI0009ED2E3C ---QFRQQLFAAAPQGSGRIGVAALDLTTGETV-SILGDEPFPMASTSKIAVAATFLAGVD -AGKYSLFHQYPLEVPVASKSSNVAPTKPGQMMSAQTLIERMITRSDNAATDALLKAVGGP -KAVTQWVHKTGLTGFRIDRDIATLVRSRHVDVRDSTPPDQMVKLIAGLHEGKWLSASSRG -LLLGAMTRTITGRTRIKAGLPSGTVFGHKTGTLNK-TASDVGFVEMPDGRIVVMAIYVTG -QGGP-AARSAKIAEITRTLYAGf ->[subseq from] Beta-lactamase n=2 Tax=root TaxID=1 RepID=R6KHZ9_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLVATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQENDADNAAIIASISKIVYDT- ->[subseq from] Class A beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A537MKE2_9PROT ----LTARIRELGRAFEGRVGIAVRDVDTGWVA-DWQGDRFYPQQSVSKFWVALTALQRAD -AGDLDLDRRVTVTRNDLTLHQPIAQQVGANGTTLNDLMFRALTQSDNTCNDIVLRHAGGP -AAVREMLTRNRLDGIRFGPGERLLQSRYVEDPVDGATPNGITNGLARLQRGELLSAESTR -RLLTIMSQTHTGPNRLRGGLAAGWTISHKTGTGQQAGYNDIGILHAPDGHHYALAVMIGR -TSTPLPARMELMQDVVRAAIAY- ->[subseq from] Beta-lactamase n=1 Tax=Legionella brunensis TaxID=29422 RepID=A0A0W0SUJ5_9GAMM ---ELAKKINRIEEKLNTVMGITAIHIEKNKIV-AHNGHKRFFMASTIKLPIALAFLHRVD -EKKDSLNRVIKLDSNNSVPGSGALYHLFEKKMSLRQILIHMLSNSDNSASDTILQVVNGP -GYVTKRMYALGFKNILINRSILEILLHFQNDIRDTTTPDDMAKLLVKLYKREALSESNTK -VLMDIMEKCRTGRSRIKGLLPPGVKVAHKTGTWAYRFASDVGIITLPNNGHIAIAVYVKS -QAASDYGRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI0008416FB6 ---SLLKEINNITKGKKATVAVSVLGIEDNFQLsNNNGQLKMPMMSVFKFHIALAILNQTD -KGNLTLDQKILVKKSDLLEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT -QAVQKFVNSKGIKNIQIKYNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD -FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN -STESEEINYSIIAQVSKAVFDY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000999A900 -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKVLVKKSDLLEWSPIREKYPDGNLPLSEVITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMSKKVQAPYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase class A n=1 Tax=Pleurocapsa sp. PCC 7327 TaxID=118163 RepID=K9T1R6_9CYAN ----LKAKLEALAAKYKLQPGVFFVDLDSGNYV-NVRGEQGFSAASTIKIPILIAFFQDVD -AGKARLDEMLTMKKELIGGGSGDLQQQPGKQFSALETARKMIVISDNTATNMIIERLGGI -KALNQRFQDWGLTSTAIHNSLPDLEGT------NTTSPRDLAHLLAMVNRGELVSLKSRD -RLLGIMQETQN-RNLLPQGLEKDATIAHKTGDIGS-VLGDAGIVDMPSGKRYIASILVKR -PHND-GNAKKLIQGISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. MI1205 TaxID=407020 RepID=A0A126R543_9SPHN ----LLGEFARFATLSDGTVGIAVRDLHNGETL-QYNGDTLFPMASIYKVAVAGKILSLAD -AGTLRLDEKLP---------------RLGTPLSVTTLLDLMLTRSDNEATDTLVARAGGP -QAVHGWLKSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIHHGKALKGSSTA -MLLGIMSRCKTGKARLVGMLPPGTPIAHKTGTLN-GLGNDTGIITLPDGRRIAISVFVMK -DHRGHAARDRIMAEVARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Yersinia enterocolitica TaxID=630 RepID=A0A0H5GRY1_YEREN ---SVDKQLAELERNANGRLGVAMINTGNGTKI-LYRAAQRFPFCSTFKFMLAAAVLDQSQ -SQPNLLNKHINYHESDLLSYAPITRKNLAHGMTVSELCAATIQYSDNTAANLLIKELGGL -AAVNQFARSIGDQMFRLDRWEPDLNTARPNDPRDTTTPAAMAASMNKMAERK-------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Legionella cherrii TaxID=28084 RepID=A0A0W0SAG3_9GAMM ---ELIKKLNAIEKNSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDSRNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -KYVAQRMSALGLKNIFINRSIMEMFVRFEKDIRDTTTPYDMAKLLVKLYKKQALSESSTN -LLMNIMEQCRTGRSRIKGLLPSNVKVAHKTGTWSYRFVSDVGIITLPNNGHVAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Olivibacter jilunii TaxID=985016 RepID=UPI00102F4467 ----LRRQIKEIILTGNAEVGVSILGIEDNDTL-SVNGYKHYPMISVFKFQIALTVLNKVD -KGELSLNQKIFIKKDELLEWSPFREKYPEGNITLKESLQWMVSHSDNNICDILIRLVGGV -HAIDTFIAS---PNFVIKNNEEEMHRNWDTQYVNTITPNFSTQQLKQFYEGRILTKSSTE -FLYKTMVETVVGPNRIKGKLPANAEVAHRPGSSFTAAVNDVGIIQLPNGKHFAIAVFVYN -TTEKYKTAEDMIASIAKATWDYy ->[subseq from] Beta-lactamase n=1 Tax=Taibaiella sp. KBW10 TaxID=2153357 RepID=A0A3N6ZXF8_9BACT ----LRKKIEGIISNKKADIGISIINPGEHDSI-QVNGDRFYPMLSTVKFPIALTILHKVA -AGELSMTQKIFIKKAVLLKWSPFREKFPGGNISLEEAMQWMICYSDNNMTDMLLRLIGGP -DSVQHFINS---KQLIVKNNEEEMHKDWASQFVNEVTPNEATRLLMMFDKGAILNKENTQ -WLYNTMVKNTTGVKRLKGKLPENVKVAHRTGTSFTGAINDIGIIELPDGKKIYIAVFIHD -TYEKFDDGEAIIAAIAKEVYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Nostoc sp. (strain ATCC 29411 / PCC 7524) TaxID=28072 RepID=K9QTL3_NOSS7 -----KTAVQDLAAANNLTPGVFLVDLDTGGYV-DINGDSSLPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQEMIAGGSGNMRFKPAGTYAALEVAKNMMTISDNTATNMLIARLGGI -EAINQRFRSWGLTSTAIRNPLPDLSGT------NTTSPKELVNLLAMVSQGKLVSMRSRD -QILDIMRQTER-DHLLPSGLGTGARAYHKTGDIGT-LLADAGVIDTPTGKRYVAAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] serine hydrolase n=1 Tax=cyanobacterium PCC 7702 TaxID=1173021 RepID=UPI000381C301 ------TAVQDLVANNNLTPGVFIVDLDNGGYV-DINASSSFPAASTIKIPILIAFFQDVD -SGKIRLDEPLTMQKTMVVGGSGDMQKPVGTKFTTLEVATKMITISDNTATNMLIARMGGI -DALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAMVNQGNLVSMASRD -RILDIMRKTVR-NHLLPTGLGEGATIAHKTGDIGT-MLADVGLVDLPTNKRYVVAVMVKR -PNND-PRAEKLISSISGAAYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Elizabethkingia sp. YR191 TaxID=2135666 RepID=A0A2T5RTV8_9FLAO ---ELLEKINSITKGKKATIAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMAKKVQAPYANYTTTASMVKTLKAFYIGMFLSKRSTA -FLMEIMTKTNTGMTKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKN -SMETEEVNCGMIAQISKVVWDT- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. (strain ATCC 29411 / PCC 7524) TaxID=28072 RepID=UPI00083AE95F -----KTAVQDLAAANNLTPGVFLVDLDTGGYV-DINGDSSLPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQEMIAGGSGNMRFKPAGTYAALEVAKNMMTISDNTATNMLIARLGGI -EAINQRFRSWGLTSTAIRNPLPDLSGT------NTTSPKELVNLLAMVSQGKLVSMRSRD -QILDIMRQTER-DHLLPSGLGTGARAYHKTGDIGT-LLADAGVIDTPTGKRYVAAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Hapalosiphonaceae cyanobacterium JJU2 TaxID=2109628 RepID=A0A328IIJ4_9CYAN ---SLKTSVQSLASANNLTPGVFVVDLENGSYV-DINASASFPSASTIKIPILVAFFQDVD -AGKIRLDEMLTMEKEMMVGGSGDMRYKPAGTFKALEVANKMMTISDNTATNMLIARMGGI -EALNQRFRNWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLLNMTSRD -RILGIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR -PNND-PSAEKLIGLISKAAYQQf ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A108T9G3_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDTDNAAIIASISKIVYDT- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=UPI0012316B5B --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDTDNAAIIASISKIVYDT- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0007398EBC ---ELLEKINTITKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAILNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMAKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGMITLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=unclassified Bacteroides TaxID=2646097 RepID=A0A416WDN7_9BACE --kELEKRLQETIANKKAQIGIAVIM-NGRDTL-VVNNDCRYPMMSVFKLHQALAVADDCH -RRGRSLDTPVYIRKDDLKPYSPLRDKYPDGNLSIKELLEYTLLLSDNNACDILFSQTGGT -ETADKYIRSLGIEQFSIKVTEDEMHKDMNTCYLNWSTPLETAKVIELLLNKELFGREYQH -FIKQTMISCQTGKDRLPLPLETNAVIGHKTGTGDRNGTNDVGFVYLPDGQRYTIAVFIKD -SEESAQATSQIIADISRVVYQY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nodularia sp. NIES-3585 TaxID=1973477 RepID=A0A218Q7S2_9CYAN -------TVQNLAANSNLKLGVFFVDLDTGSYV-DVNSATSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMEKDMISGGSGNLQQKVGSQYTALEIATRMSTISDNTATNMLIARLGGM -EALNQRFQSWGLSATAIRNPLPDLAGT------NTTSPRELGNLMAMVNQGNLVSLRSRD -LILDIMRRTER-NHLLPSGLGTGARIHHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR -PNND-PEAEKLISAISRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Blastomonas sp. CACIA14H2 TaxID=1419876 RepID=W9BVW3_9SPHN ---GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD -RGEVSLDQEVTITANDLTLHQPLAARVAREGATVRSLINEALTASDNSANDALLRTAGGP -GAVNDFLRRKGLSNIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPQRMQLMQAVSRAV---- ->[subseq from] serine hydrolase n=1 Tax=unclassified Anabaena TaxID=2619674 RepID=UPI00082D3847 ----LKNAVQELAANANLRPGVFLVDLDTGGYV-DINGDNSLPAASTIKVPILIAFFQDVD -AGKIRLDEILTMQQDMIAGGSGNMQFKPAGTYAALEVAKKMITISDNTATNMLIARLGGI -DAINQRFRSWGLTNTAIRNLLPDLSGT------NTTSPKELVNLLTLVSQGKLVSMRSRD -QILDIMRQTER-DHLLPSGLGTGARVYHKTGDIGT-LLADAGLIDTPTGKRYIAAVMVQR -PNND-PRAEKLISSISRAAYQQ- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A139JZ57_BACT4 ---SLEDQLKQAIKGKKAKIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] serine hydrolase n=1 Tax=Nodularia sp. NIES-3585 TaxID=1973477 RepID=UPI000B5C9633 -------TVQNLAANSNLKLGVFFVDLDTGSYV-DVNSATSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMEKDMISGGSGNLQQKVGSQYTALEIATRMSTISDNTATNMLIARLGGM -EALNQRFQSWGLSATAIRNPLPDLAGT------NTTSPRELGNLMAMVNQGNLVSLRSRD -LILDIMRRTER-NHLLPSGLGTGARIHHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR -PNND-PEAEKLISAISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. AL-1 TaxID=1499682 RepID=UPI0009DDA20C ---QFESRLDEIVSGHKAFVGVAIR-TPDGKTV--ARNDSLLPMMSVFKFPVALAVLDRMQ -REGTPLTQPISITPDLLLPYSPMRDSLPTGGLTLGQLLRYTVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE -SEENDAANAAIAAAVSRAAYEYf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=A0A3E5G5F6_9BACE ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQKYKD -FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SAENNQENSKIIADISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Elizabethkingia anophelis R26 TaxID=1246994 RepID=A0A290MRX3_9FLAO ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQGFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDESEKIISDIGRAAYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B9CUG3_9PLAN --dDLKHQLMPLIQSHGGNVAVSVLNLKTGYRF-DYRSTEVMPTASLIKLPVMIEAYRQIS -SGDLSLDVEIVLKAEDKVPGSGILTKHFGDGLKLRDAIQLMIGYSDNTATNLVIDQI-GL -AATAKTMAEMGYPETKLHSRVYRGSERSRKYGLGSTTSSDIVSLLERLHKRDLVSPKFSD -VMLKHLRDCEA-TAQLPRLLPPNLVIAHKSGAVSN-ARCDAGIIYAPNGA-LAICTLTSQ -NESKDNAAELLNARIAKTVFEHf ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI000694067B --kALEQELVELGENFDGVTGIAVTEADTMATM-AHDGDTPFPQQSVSKLWVAMTALDLVD -NGALDLEEPVTLRSEDLTVYQPTRNIVRSRGTDYGDLLDRAITQSDNTANDRLLRRVGGP -QAVEAFMRRNGIAGVQFGTDERTKQSAYLSDPMDGAKASAMAKALARLARGDLLSEESTD -LILSTMEETKSGPRRLKGGVPNGWTFGHKTGTGQQSGYNDVGILTAPDGSQYALVVFIGR -TRASYAARMEMMQEVTRSVVRY- ->[subseq from] Beta-lactamase n=1 Tax=Fluoribacter bozemanae TaxID=447 RepID=A0A0W0RS01_FLUBO ---ELIKKIKDIEKKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDSRYSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -RYVAKRMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPNDMAKLLVKLYKKQALSESSTE -LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Fluoribacter bozemanae TaxID=447 RepID=UPI00104103ED ---ELIKKIKDIEKKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDSRYSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -RYVAKRMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPNDMAKLLVKLYKKQALSESSTE -LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHIAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Candidatus Hamiltonella defensa TaxID=138072 RepID=UPI00031282EE ------------------------------------------------------------- -----------------------LTKQNLADGMTVAELCSAAITVSDNTAANLLLSTIGGP -KGLTSFLQKTGDQVTRLDRWETQLNQALPGDERDTTTPKIMAQTLHNLLTGKILSAKSRQ -QLQTWMVMNKVGGPLLRSVLPANWFIADKTGAGNHGSRGIIAALGADGKPSRIVVIYLTE -TQATMDELNKQIAEIGASLIKHw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI0006D537EB ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNETHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI001371BBEA ---MLKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Blastomonas sp. AAP53 TaxID=1248760 RepID=UPI000308EED1 ---GLRDELAQLWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMAVLEKVD -RGELALDTEVTITRDDLTLHQPLAARVAREGATVRTLINEALTASDNSANDALLRTAGGP -AVVNDFLRRKGLSNIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTQ -LMLDTLGRTRSGPQRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE -TTASIPARMQLMQAVSRAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonadaceae bacterium 3R27C6 TaxID=2502220 RepID=UPI0010F5C949 ----LNDRIYELWRAFPGKTGIAVQRIDGEWSL-SQRGGELFPQQSVSKLWVALTVLDAVD -QGRMTLDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -AAVRAFITKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TTAGIPARMALMQSVSSAVAEY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sporanaerobacter sp. PP17-6a TaxID=1891289 RepID=A0A1G4FG15_9FIRM ----LENKIREFIKNQKGNVAVAIKDLKTGKEI-KINENLVFPSASTIKLSIMSELFNRVN -AGSLNLNDKVELTENMKTGGDGILKEELGHKFTLKEIMTLMIIISDNMATNILIDLL-GM -DNINKRIKDMGLKNTRLQRKMMDSQAA-KEGRENLTTANDLCLILELIYRGENINEECSR -MMLDILKRQQV-RGRLDLYLPEDVIIAHKTGDLDC-LEHDVGIVYLPHRE-YIICVLTNE -TE-TNKDGREIIGKVSKMVYDEf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000665F26C ----LKKTLESIISGKRATVGISIMGPDTKDVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPTGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Elizabethkingia sp. YR191 TaxID=2135666 RepID=A0A2T5RRU4_9FLAO --sQLKKTLESIISGKKATVGISVMSPDEKEVT-GINADQMLPMLSTVKFPLALAVLHEVE -KGKLSMAQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVSGKKRLKGNLPTGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Coprobacter fastidiosus TaxID=1099853 RepID=UPI000240E6C3 --rELKMRIASVLKEKRATVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH -KNNLSLDTEIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT -KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLFRDEYGN -YLRKIMIETSTGNDKIKAGLPERVVMGHKTGSSDRNGDNDLAFVQLPDGQRYCIAIFIRD -SKEDDKTNAAIIASVSKVVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadales bacterium 63-6 TaxID=1895846 RepID=A0A1M3I5Z2_9SPHN ----LEQYVAKLADGTNGRIGVAAVDLTTGEQV-SVLGSQRFPMASTSKIAIAATFLEGVD -KGRWKLDDKFPLMVPLPSQSTKVAPVKAGRMLPARELIDLMLVHSNNQATDGLLAVIGGP -RAVNEWIKRAGIDGFSLDRDIATLVRSLYIDPRDSATPLAMVRLLQGLHDGRWLSKESRE -LLMVTMANCKTGPNRIKGQMPTDVMVAHKTGSLYN-TSSDVGIITGPDGHSIAVAIYVTG -GGMNRGYRIDRIATIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A0W8ETH1_ELIMR ----LKKTLESIISGKKATVGVSIMDPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMHQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWIVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=4 Tax=Bacteroides TaxID=816 RepID=A0A679H3X1_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEESNQENSKIIADISRIVYEY- ->[subseq from] Class A beta-lactamase n=1 Tax=Mesorhizobium sp. TaxID=1871066 RepID=A0A3S3KRN3_9RHIZ ---RLRLQFEALANAHPARVGICAQG-RVLPPI-CVNGEQRFSLRSAVKIVIAAAVMQAVD -EQRMALDDRITIRREDLSVIQPTADIVVEKGTTIGDLVRRAVVDNDNAAADVLIARLGGT -SAIQAFLHKAGLQDIRIDRTERELQTAYLRDPRDTATPRAMVAFLQRLATGTLVSAASTA -YLLGVMEDTVNIPDGLRPGIPSDWTIGHRTGTSPNGVTNDVGILTTPWGDRIAVAVFVAE -SRADESERAALIAAAARAITSAy ->[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter marensis TaxID=543877 RepID=A0A2W5AST8_9SPHN ----LAQRVAMLAAGDQGRIGVAAIDLTSGQMI-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWTLSSEFPLLIPVQSPSSARAPVRPGSYMTAYDLIDLMITRSSNPATDALLAAVGGP -AAVNDWARRNGITDFTLTRDIATLVRANRIDIRDSATPMAMAQLLAGLHQGRFLSARSRQ -VILDAMERCKTGTRRIPALLPLTARVQHKTGSLNN-TSSDIGIFRLADGRPIAVAIYVTG -QG-TRLNRERRIAEIARGIYDGy ->[subseq from] Serine hydrolase n=2 Tax=Hydrococcus TaxID=1616833 RepID=A0A1U7HAC6_9CYAN ----LKAKLEALAAKYKLQPGAFFVDLDSGDYV-NVRGEQGFSAASTIKIPILIAFFQDVD -AGKVRLDEMLTMKKELIGGGSGDLQQQPGKQFSALEIARKMIVISDNTATNMIIERLGGI -KALNQRFRDWGLNSTAIHNSLPDLEGT------NTTSPRDLAHLLAMVNRGELVSLKSRD -RLLGIMQETQN-RNLLPQGLEKDATIAHKTGDIGS-VLGDAGIVDMPSGKRYIASILVRR -PHND-GNAKKLIQGISRIAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SG61-1L TaxID=1603897 RepID=A0A0P6X4B8_9SPHN ---ALEQYVAKLADGTNGRIGVAAIDLTTGEQV-SVLGSQRFPMASTSKIAIAATFLEGVD -KGRWSLDDKFPLMVPLASKSTKVAPVKPGRLLPARELIDLMLVHSNNQATDGLLAVIGGP -KVVSEWVKKAGIDGFSLDRDIATLVRSLYIDPRDSATPLAMTQLLKGLHEGKWLSKSSRD -LLIVTMENCKTGANRIKGQMPADVQVAHKTGSLYN-TSSDVGIITGPDGHSIAVAIYVTG -GGMDRNYRTGRIATIARAIYDGf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0003FE7221 ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGIKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKRMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWD-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A1L6JFV0_9SPHN ----LQSSIHALARNFGGVVGVSVRSLDAGWQI-DANGTRRMPQQSVSKLWVAMTVLDARD -RGRLTLDDPVTLTRENLTVHQPIAALVVKNGTTVRELLLRAMQQSDNTANDRLLNLVGGP -EAVRAMIRDKGLGDIRFGPGERLLQAAYVADPIDGAAPAAIALALARLKAGEILSPSSTR -WLMTVMEASRTGKYRLRGAVPPGWSFGHKTGTGQTAGYNDVGILTAPDGKAYSIAVMIGD -TPRPIKERQELMQGVVAAVVAQ- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingorhabdus sp. Alg231-15 TaxID=1922222 RepID=UPI000D560857 ----LEREIADLWRSFPGKTGIAIKSIDNGWSI-GHREDQNFPQQSVSKLWVAMALLDKVD -QGRISLSDSIRIGPDDLTLYQPLAAEVKREGKSVFTLLEKSLAFSDNTANDALLRHAGGP -DAVNDFIRRSRLGKIKFGPGERLMQSAYLADPIDGASPGAIVNALDRLARGDLLSENSTR -LLQSILKRTRSGPKRLKAGVPAGWEFLHKTGTGQATGYNDVGIMTAPDGSRYAVAVMLGD -TTASVPERMRMMQSVTRAVARY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000CE93CCF -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGISKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Reichenbachiella versicolor TaxID=1821036 RepID=UPI000D6E4502 ----LKKEIQNTLKDKDATVGVSIIGPSSLDTL-SINGDLHLPMQSVYKFHLAAAVLHRVD -QGELNLSDTIEITKEQLDNWSVIRKDYPNGGLSLGQVIKYTVAVSDNVGCDLLFEMIGGP -SVAQEYMNKIGITDIAILHNEETMQSEWSIQYLNWTTAKSATKVLKTLYEDNLLSTASHQ -FLWDVMKSSWVGKLSMKTYLPETTVIAHKTGHSGTAAQNEIGIIWLPNGDYFYISILVSD -SSEESEVNRKLLADITKLTWDYf ->[subseq from] serine hydrolase n=1 Tax=Blastomonas sp. UPD001 TaxID=2217673 RepID=UPI000E350EB0 ---GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD -RGEVSLDQEVTITANDLTLHQPLAARVAREGATVRSLINEALTASDNSANDALLRTAGGP -GAVNDFLRRKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPQRMQLMQAVSRAV---- ->[subseq from] Beta-lactamase n=1 Tax=Sutterellaceae bacterium TaxID=2026794 RepID=A0A3D3SEQ5_9BURK ---DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANNDDQYPLMSVFKFHIGLAVLKKME -KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI -QNVNDFIKNLGIDRIQLIETEKSMEQDIRKSYNNWSTPLSVTQLLRKVYTEKVLSDEHFA -FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD -SKETDAANAKIMADIAKKVYSHy ->[subseq from] serine hydrolase n=1 Tax=Scytonema millei TaxID=1245922 RepID=UPI0005845436 --------------NAKLFPGMFFIDPETGAYL-DWNGDTTFAAASTIKFPILVAFFQDVD -AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI -AALNQRFRNWGLTVTELRNLLPDLEGT------NTTSPKELAQLMVAVQKGDLISVKSHD -RLLNIMRRTHT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLPSGKRYIAVAMVKR -PHN-NAQAKELIRQVSRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522KKB4_9GAMM ---TLQGRLEALARQAPGTLGITVFDLQSGKVW-RVNAQRAFPMMSVFKAPVAAAVLDRIE -HHALSMEQPVVIRRSDLESGA-IREHFKGDQFTVRQLLTEAVSKSDNTAVDALLKVMGGP -RIVTAFLHDHGIDGMRVDIGENGFRSAFLADPRNRSTPDAAANFLRKLWDGQLLPPSSTR -YLLDLMYAQTM-PNRLRRGLPMGARLADKCGTSYTAAYNDIGILSWPDGRAVVVAAFLTA -STASKDERDAIFADLARTVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Shigella flexneri TaxID=623 RepID=UPI0012E7416F ------------------------------------------------------------- --------------------PSPLTSQHIADGMTVSELCNAAITTSDNTAANLLLSTIGGP -EGLTHFLRSTGDSYTRLDRHEPSLNEAKPGDERDTTTPAAMAQTLQKLLNESVLTEKSRK -KLISWMQEDKVGGPLFRSVLPAGWMIADKTGAGDHGSRGIVALLGPGGKPSRIVVLYITN -THSSMNELNEHIAGIGDSVIKNw ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas koreensis TaxID=93064 RepID=A0A2M8WDF0_9SPHN ----LQSSIHALARNFGGVVGVSVRSLDAGWQI-DANGTRRMPQQSVSKLWVAMTVLDARD -RGRLTLDDPVTLTRENLTVHQPIAALVVKNGTTVRELLLRAMQQSDNTANDRLLNLVGGP -EAVRAMIRDKGLGDIRFGPGERLLQAAYVADPIDGAAPAAIALALARLKAGEILSPSSTR -WLMTVMEASRTGKYRLRGAVPPGWSFGHKTGTGQTAGYNDVGILTAPDGKAYSIAVMIGD -TPRPIKERQELMQGVVAAVVAQ- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A412N1H3_9BACE --qTLESKIDDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN -KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD -FLWNTMIATSTGSNKLKGLLPSNTIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMVYDEy ->[subseq from] Uncharacterized protein n=2 Tax=Alistipes onderdonkii TaxID=328813 RepID=A0A1Y3QXI4_9BACT ---QFESRLDEIVSGHKAFVGVAIR-TPDGKTV--ARNDSLLPMMSVFKFPVALAVLDRMQ -REGTPLTQPISITPDLLLPYSPMRDSLPESGLTLGQLLRYTVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE -SEENDAANAAIAAAVSRAAYEYf ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces violaceusniger TaxID=68280 RepID=A0A4D4KXG4_STRVO ------------------------------------------------------------- -----------------------MTEKHVDTGMSLGALCDAAVRYSDNAAANLLFDQLGGP -KGLDAILEKLGDDVIQMENIEPELSRWVPGETHDTTTPRAMVKDLRAFVLGDVLGKGERA -QLTKWLRTNTTGDELIRAGMPKGWQVGDKTGSGSYGARNDIAVVWRPGAAPLVMAIMSYR -GDKDTPFDNKLIADAASVVAD-- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0013662DA1 -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANANLKMPMMSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPIREKYPDGNLPLSEIIAYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGIKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQVSKIVWDA- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. 1_1_14 TaxID=469585 RepID=D7I974_9BACE ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G293_9BACT --sKFEHRLQEIAARVDGVMGYAVLDVTSGDRF-GHLERDVFPTASTIKLAIVYELFKQVD -EGKLRLDQTITLDRKHAVGGSGVLVAMGTPTLSIRDYATLMVMLSDNTATNVLIDLT-GM -DNVTRRMAGLGLSATKLRRRMIDLAAAKRG-DENVSTPADIVRLLEALSKGEGLTSSSRD -EALALLKKPKA--SRLRKGLPPGIEAADKPGELE-GVRVDAGIVFAKNR-PYILCVMTTY -LK-DEAEGERAIEDASRAAYDYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T5B9_9BACT ---EVLQEFKSAENKSHGTVGAAAMDLQTGKRI-DINGDKPFPMQSVYKMPIAMAALGQVD -AGKFALDQKFTLKPEDYAQYSPIRDKNPDGGFSLLDLIRPTVSISDNSTSDYIMKLIGGP -GAVMTFLTDIGTSQIIVKNYEREIQSDWSLQYKNSSTPYAMVDLLGRLHLGEGLTSGSRE -TLLQIMRDTTTGPNRIKGKLPKSLIVAHKTGTSGAGATNDAGIITLPDG----------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000B35DCCD ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI000E5225BA ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKTYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDRHAYSIAVFVKD -SAENNQENSKIIADISRIVYEY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Fischerella sp. NIES-4106 TaxID=2005456 RepID=A0A1Z4TQF6_9CYAN ---SLKTNVQSLASANNLTPGVFVVDLENGSYV-DINASASFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMEKEMMALGSGDMRYKPAGSFKALEVANKMITISDNTATNMLIARMGGI -EALNQRFRSWGLNTTVIRNQLPDLDGT------NTTSPKELGNLMAMVSQGNLISMTSRD -RILEIMRNTVR-NQLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTGKRYIVAVMVKR -PNND-PSAEKLIGSISKAAYQQf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides timonensis TaxID=1470345 RepID=UPI0004B08D60 --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLTPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI -DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7EMM5_9PLAN --qSLEEKLKTIADSHKGVVAIAVKQLDTNESC-YLNADRVMPTASLIKLPIMIEAYRQAA -VEDLDLQKLISLRDEDKVPGSGVLTDHFSDKLPLIDCIQLMIAHSDNTATNLVLDEI-GL -PSTNRTMKRLGCPNTRVNAKVYRRDTSIAPEQSGSTTAREMVRLLEQLDQGQLVNKASCD -AMRRHLLTCQD-QTKIARLLPPGVSVAHKTGAVSR-SRTDAGLIEGPSGT-IAICVLTTD -NERDDNEANQLCGVLARAAYDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas populi TaxID=2484750 RepID=A0A4Q6Y851_9SPHN ---ALARSINAVARSFDGRVGVAVRSIDKGWTI-ESNGDVRLPQQSVSKLWVAMTVLDFRD -SGRLTLDDPITLTRADLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP -SAVRDFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKGELLSPMSTA -FLISTMESSKTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD -TPRTIPQRQELMQSVVQAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 030167 TaxID=2016500 RepID=A0A255G9X6_9ACTN -----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT -PDPKVLDRPVFLPPEAICEGPAWFAEQIATRPSVAEVCRAAIQLSDSTAANALLSLTGGP -DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR -RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS -PRPDTERVNEIFAILAREAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A174NCG0_BACT4 ---SLENQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNEIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKDVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2W6SVI6_9SPHN ----LAQRVAMLAAGDQGRIGVAAIDLTSGQVI-SILGDQRFPMASTSKIAIAATFMEGVE -QGRWTLSSEFPLLIPVQSPSSARAPVRPGSYMTAYDLIDLMITRSSNPATDALLAAVGGP -AAVNDWARRNGITDFTLTRDIATLVRANRIDIRDSATPMAMAQLLAGLHQGRFLSARSRQ -VILDAMERCKTGTRRIPALLPLTARVQHKTGSLNN-TSSDIGIFRLADGRPIAVAIYVTG -QG-TRLNRERRIAEIARGIYDGy ->[subseq from] Uncharacterized protein n=1 Tax=Novosphingobium sp. SCN 63-17 TaxID=1660120 RepID=A0A1E4N3G1_9SPHN ----------DIERQYGGRLGFAVA-FSSGGIV-NWRGHERFAFCSSFKLSLAALVLTGAE -KGEWRLDEKLPFGKGEVLFNSPALQARLGLGISMAEAAEAVQKQSDNGAANLLMRRMGGF -DRVNRFWRGLGDMVSRLDDYETALNRVPPGSLRNTTTPEAMADNLFRMFRQGALSPAVVT -RLKDWMHDTTTGAKRLRAGLPGNWWAGDKTGTGLPGTYVDLAWVEPPDLAPFAIAAFYQP -PKPTDSNAETVLAQVGQNIAQ-- ->[subseq from] Beta-lactamase n=2 Tax=Altererythrobacter namhicola TaxID=645517 RepID=A0A1C7D4Y1_9SPHN ----VERNIAALADGSNGRIGVYALDLSTGMEV-SVLGDQRFPMASTSKIAIAATYLAGVD -QGRWTLQTEWPLLWPLRSKFSSARAPVKAGKMSAYELIDLMITRSSNPATDALLAAVGGP -QAVNDWARSVGMTEFTLTRDIATLVRAMHVDVRDSASPRTMGYLLAGIYNGHWLSASSRN -VILSAMERCITGKRRIPAQMPDYVTVGHKTGSLNN-TSSDIGFLTMPDGRTIVVAIYVTG -QG-SKRQREARIATIARGVLD-- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00136E9996 ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E3Y640_9BACT ----LEQELLRLGALSGGKMGIGVIHLETDQRL-YINNKERYPLASTYKVPIAVQLLKRVE -NGEITLNDMTDVQPKDQHPGSGILSDLVAPGLSLRNQLELMMIISDNSATDICLSAAGGS -KKIKRLLKKHKIRDMSIDRPTIGIIGKFEKDXRDTATPQAMAELLQMIWSNKILEKENSE -LLIDIMSRCQTGEGRLKGXLPKDTYVAHKTGTIG-ATTNDVGIIRLPNKGNVVVVAFVKD -SDLTIPERERAIAHVARSVHDYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A523EA70_9BACT ---RLEHKIRTIADGVDGVVGVTIQDLTTAERF-ALRGDTVFTQASAIKLPVLVELFRQVE -QGRYGLDDIITLERDDIVPGSGVLQRLTPGSLTLRDVATLMVTVSDNTATNMIIDRV-GM -ENVNQTMARLGLPHTKLQRKMMDRE-AWLADRENLSTPNEQARLLELIHRGDVLSDASRK -ELLHILSIPKP--SRIRPLLPRGTRVAHKTGTVA-GVVVDVGIVYLEGR-PFIIAGMANW -LV-DGAEAERALEQIALAAYQYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJU5_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPNSKKDTSTPAAFGTTLNKLIPNGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQA--------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium cucumeris TaxID=1813611 RepID=UPI000F45AE09 ---DLKKTIESILSNKKADVGVSIIDPYHKERI-QINGNKLYPMLSTVKFPIALTVLNKIE -KGELSLQQKLLIKKEELLEWSPFRKEYPDGNISLEEAIKWMVSYSDNNLTDILLRLIGGP -EPVQQFINS---KDFIIRNNEEDMHKDWESQFVNKITPNETTKLLEAFNNGKILNKKHTL -WLYNAMLNNTTGTKRLKGNLPQHVKTAHRTGTSFTGAVNDFGIIEISGKKKFYIAVFIHD -TYEKFGDAEAIIADISKAAYEYy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E3D88AD ------------------------------------------------------------- ------MNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGP -QAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLD--ERK -QLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGNGTRGVIAVMWPPKHAPIIAAIYITQ -TKATMEERNAAIASIGKAI---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A224A860_SHIFL ----------------------------------------------------------RSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Rhodopirellula sp. JC645 TaxID=2605748 RepID=A0A5M6DIB1_9BACT --eELAERVQPLVDKHAGDVAVVIKNLDGAGRF-QFRQDAPMATASLIKLPLMVTAYRRID -AGELEANRLLVLTEADKVPGSGILTDHFSGGLPLQDAIRLMIRYSDNTATNLVAEEV-GL -ARTAEMMASLGLQQTRMHSKVFRRDTSIDLDRSGSTTAAEMAALLERLYRDELASDASCQ -AMKAHLRACDD-GSKLAAGLPPGTPIAHKTGSVSS-VRTDAGIVQGPDGQAFLICVLTEN -NQTEDNAADKLISEIARAAYD-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. EP60837 TaxID=1855519 RepID=A0A173KVZ3_9SPHN ----LLGEFARFATLSDGTVGIAVRDLNNGETL-QLNGDTLFPMASTYKVAVAGKILSLAD -AGTLRFDEKLA---------------RLGTPLTVTMLLDLMLTRSDNEATDALVARAGGP -QAVNGWLQSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIQHGKALKGASTA -MLLGIMSRCKTGKARLVGMLPPGTPVAHKTGTLN-GLGNDTGIITLPDGRMIAISVFVMK -DHRGHAARDRIMAEVARAAYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. HY041 TaxID=2500547 RepID=UPI000FE3E720 ---PLEKTINSIIKNKKATVGVAVIY-DGKDTL-TVNNNYHYPTMSVFKFHQSLAVLDYMD -KNLLPLETPLFLKKSDLRPYSPLRDERPEGNISIGELVKYTVTKSDNNTSNALFHYMSGT -RMTDLYIRTLGIKDFAITATEAEMSEDFNNQYLNWTTPLAAARLLEVFLKDDLVSKDTRD -FLVNAMVQTTTGPDKLKALLPATTKIGHKTGSSARSADNDIGFVALPNGKQYSIAVFVMN -SMESDKTNARIIADISKAVYDFy ->[subseq from] CME-2 extended spectrum beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=A4GRC1_ELIME -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKTLYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLANGKHYAIAVFVKD -SMEGEEVNCGIIAQVSKIVWDA- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D0EC894 ----WQQAVENVLKEAPGIYGIAAVHLETGETV-GHLDEELFQLASTFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWVLLNSIPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVND-VVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium HGW-Elusimicrobia-3 TaxID=2013765 RepID=A0A2N2EM74_9BACT ----LVEDLEKASRAYSGRVGIYIKDLETGKSW-EYNADRRFPSASLIKVPIMAAVFERIR -DGQLSLDTQIKLTRGLRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDSV-GM -DYLSGAFRGMNLEQTNITPEGMSLSSR-PVRRENYTTAREMGGLMERIYAGKLVDREASE -FMLDVLKHTKS-RTRLRRGLPLGWEIGHKTGLLRK-ACHDVGVVFSPRGD-FVIAVLTAE -VP-SYSSAKTFISRVAKLTYKYy ->[subseq from] Beta-lactamase n=4 Tax=Bacteroides TaxID=816 RepID=R6W5T9_9BACE ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHVYSIAVFVKD -SAENNQENSKIIADISRIVYEY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A222U9G9_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPA--------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SUK8_9BACT ------AAVQKLAHSLKARVGMAAVMLDTGEAV-AVGDETAYPMQSVFKFVLALSVLKRVD -QGALNLEHIIHIRPEQLVKWSPLRERFPQGGFSLKELLRVTVQGRGNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHDLQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] class A beta-lactamase n=1 Tax=Litoreibacter sp. K6 TaxID=2601869 RepID=UPI00130A0CCC ---------EVIELSLLGDIGVYALDSENDRAS-GWSEDYRQPSNSTVKFLIATAVLYRVD -AGQERLDRGIHVDDMMPLSHSPVLENAHGDTMPVSAICAAMMTRSDNAAANLLLESLGGP -QSLTLWLRQMGDQVTRVDRYLPDLTTPPESPDSDSTTPAQMVRNMRTFLTGSAQLEGSRL -LLKNWMTENATGAHRLRAGVPQGWQVADRTGTGSDGRTSTIAAIYP-------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. HL-46 TaxID=1479239 RepID=A0A0P8D4H8_9SPHN ---SFQQRIAELAEPSRGRIGVAAVDLATGEEI-MVLGDQLFPMASTSKIAIAATFLEMVE -QGRYSLTSEFPLLLAVRSAYSSAKAPVRKGQMPAIDLIEIMITRSSNPATDALLAAVGGP -EVVNDWVQRHGIHEFSINRDIATLVRARHIDTRDAATPRAMAQLLGGLYRGDYLSDESRR -VLLGAMSRTVTGKRRIVAHIPAEARVSHKTGSLNN-TSSDIGLIECPDGRTIAVAIYVTG -QG-TRLAREQKIAAIARALYDGf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7W6X1_9BACT -------------QKSDAVIGVAAVDLQTGRRI-SVRDTERFPMGSVYKVPIAIEVLRTQQ ------LERMITIEPKDFSPWSPLRDGADGKPMTIEDLAEWMVQASDNTACDALLRIV-TP -QAVTKRMRELGVRGIRIDRQEREMAARYATDPRDTTTPDAMLALFTAIAQHDGLSPANHA -KLMHWMTETTTGPHRIKAGIP-NAAIAHKTGTMP-GTVNDVAIIDN----RIVLAIFTKA -STTPDEKAEADIAAIARGVYDA- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI000999C068 --tALKKTLESIISGKKATVGVSIMDPDKKGVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWVVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9DI69_9BACT -hsKLARQLEQTAAEFDGVMGLAVKDLTTGESF-AVNAAMVFPQASSIKITVLMELLRQAQ -AGKLKLDDRVAIKQVHMVGGSGVLQFFGDASISLRDLAVLMIVLSDNTATNILIDQV-GM -ANVNDTLAHLGLAQTRLQRRMIDTAAQ-RAGRENLSTPREMTTLLELLHGGKVLDASHTA -ALLEILKYPKENASPLRNGLPDGIALANKAGSLP-GVRCDSGIVLLPDR-PYVISVMTTY -GH-DSHAAERAISEVSRRVLEYf ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=A0A1T3IBW1_ELIME ---SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVFKFHIALAILNQAD -KGNLTLDQKILVKKSDLLEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT -QAVQKFVNSKGIKNIQIKYNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD -FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLNNGKHFAIAVFVKN -STESEEINYSIIAQVSKAVFDY- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI000751105C ---ELLEKINSITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA -FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD -SMESEEVNCGMIAQISKVVWD-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A415AJF8_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSIFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLTPYSPLRDKFPDQNISLGELLKYTISKSDNNTCDILIEYVGGI -EQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISQIVYDT- ->[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=Bacteria TaxID=2 RepID=A0A412P7V8_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSIFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLTPYSPLRDKFPDQNISLGELLKYTISKSDNNTCDILIEYVGGI -EQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISQIVYDT- ->[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L4Q5_9BACT ------AAIREIVRPLKAKVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD -QEVLNLDQKVHVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP -AAVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPSAVTFLFRMFDEGKILKKDTQL -FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN -SKDSPAVCEGTIASVARWLCTEw ->[subseq from] Serine hydrolase n=1 Tax=Chroococcidiopsis cubana SAG 39.79 TaxID=388085 RepID=A0A433W660_9CYAN -------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD -AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI -AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKDLAQLMVAVQKGDLISVKSRD -RLLNIMRRTQT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLLSGKRYVAVAMVKR -PHN-NVQAKELIRQVSRAAYQEf ->[subseq from] Class A beta-lactamase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E9TZ04_9CHLR --kSLKVELTRLADLSGGKMGIGVIHLESNQKV-YINNKDRYPLASTYKVPIAVQLLKRVE -KGEKSLEDLLDVQPEDQHPGSGIIGNFVTPGLSLRNQLELMLILSDNSATDICLTAAGGP -DQVKDILKKYNIQNMSIDRPTIGIIGKFGKDLRDTATPQAMAELLQKIWLNEILTREHSE -LLIDIMSRCQTGEGRLKGLLPPGTYVAHKTGTIG-ATTNDVGIIRLPNKGNVIVVAFVKD -SELEIPAREKAIAHVARAAHDFf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2W6SKG7_SPHSX ----LQTKLDAEARSGSARVGLAAIDMTTGDMV-SVNGDQHFPMASTVKVAIAAAFLHGVQ -RGKLSLDATYRLPTDQRKMASGIGNMRAPQRLSGAQALDEMLTRSDNTSADILLAAIGGT -DALGRWLTTAGISGQRVDRSIAELLRAPVGDRRDSSTPEAMAALLAKLRNGELLDKERTL -YLFEVMARCRTGSGRIRGLLPAGTPVAHKTGTMN-GITDDVGIVGLPNGHELAVAIFETG -AG-GARAHDRKIAQLSRILYDHf ->[subseq from] Beta-lactamase class A n=2 Tax=Arboricoccus pini TaxID=1963835 RepID=A0A212RFB3_9PROT -------------------------------------------MCSTFKGLLGALILARVD -QGKESLQRRVTYSEQDLIFTSPITKTNVAKGMSVEDLLEAMLVYSDNTAAILLMRSAGGP -AALTQFLRGIGDTVTRSDRYEPKSNQY--DGALDTTSPRAIIGSAYQILIGNVLTPASRA -RLESGMIACKPGVRRIRASLPASWSIGDRPGENVTEESNDYAIVRPPGRAPLLIATYYDD -PHRSTADREAVIRDVGSAFV--- ->[subseq from] Class A beta-lactamase, subclass A2 n=3 Tax=Bacteroides TaxID=816 RepID=A0A3E5HJ85_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLNYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Sphingomonas haloaromaticamans TaxID=653954 RepID=A0A1S1HEN3_9SPHN ----LEARIATLGQSFSGSVGIAVRDVSTGWAV-SYNAQRPMPQQSVSKLWVSMAVLDAVD -RGTISLSEPVTVRRDNLTVHQPVRAMMGANGTTYGALMRIALTQSDNTCNDMLLRRVGGP -DAVRGMILRKGLGRIAFGPGETLLQSRYLADPMDGATAEAIAGALARLKRGELLSPASTR -LLLTTMGDSRTGPQRLRAGLAPGWTLAHKTGTGQATGYNDVGVITAPDGRSYAVAVMIAS -TRQPIPVRQRLMADVVRAVVA-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI00110758AA ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAATRLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SAENNQENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter sp. zrk23 TaxID=2711215 RepID=UPI0013E171B8 -------VITDLERRFDGVVGIAVNSVDDGWKI-AANGDRRLPQQSVSKLWVAMTVLDYRD -QGRLSLDDPYTVTKADLTVHQPIATLIGDDGTTIRELLRRAMTSSDNTCNDILLRYVGGP -EAVRDFIARKGLGAIRFGPGERLLQAGYIADPPDGATASAIAGALAKLKRGELLSPDSTD -WLISTMESSRTGRNRLRGAVPAGWSFGHKTGTGQTAGYNDVGILTAPDGKTYTVAVLIGD -TARTIRQRQELMQAVVASVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. 1_1_30 TaxID=457387 RepID=F7M8L6_9BACE --tQLETQLKEAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQKQSLETRLPIKKSDLKPYSPLRDKYPQGEMSIADLLKYTLQQSDNNACDILFDYQGGP -DAVNKYIHSLGIRECAIAGTETAMHEDLNLCYENWTTPLAAAELVEIFRKKPLFPNVYKD -FIFQTMVECQTGQDRLVALLDKKVTVGHKTGTGDQIGCNDIGFVLLLGGRTYSIAVFVKD -SEENNQANSKIIANISRIVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Croceicoccus naphthovorans TaxID=1348774 RepID=A0A0G3XNJ6_9SPHN ----LNDRIFQLWRAFPGRTGIAVQRVDGEWAI-AQRGGDLFPQQSVSKLWVALTALDAVD -QGQLSLDHDVRIGPGDLTLHQPIAARVRSEGMTVRDLIESAITQSDNTANDSLLRSIGGP -DAVRSFIARKDLGPIRFGPGERLLQSAYLANPVDGATPSAIASALTRLARGSLLSPESTS -YLLDVMSRTRSGPKRLKAGLPQGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLRD -TTATVPARMALMQAVSGAVAE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Alistipes onderdonkii TaxID=328813 RepID=A0A5B3GTM4_9BACT ---QFESRLDEIVSGHKAFVGVAIR-TPDGKTI--ARNDSLLPMMSVFKFPVALAVLDRMQ -REGTPLTQPISITPDLLLPYSPMRDSLPESGLTLGQLLRYTVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE -SEENDATNAAIAAAVSRAAYEYf ->[subseq from] serine hydrolase n=1 Tax=Sphingosinicella sp. YJ22 TaxID=1104780 RepID=UPI0014083E8E ------------------------------------------------------------- -------------------------------GVSARRLMDAMITRSDNRATDQLIAMLGGP -AVVDEWLRSHGVTGMRVDRTIAQLLAARRRDVRDSSTPVAMLNLLRLIDSGRVLQPHSRA -MLLDMMARCRTGSNRIRGLLPPGTHVENKTGTLN-GYTGDVGFLTLPDGQRIAVAFFARY -GS----NRPAVIASAARAIYDNf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. 20006FA TaxID=2056888 RepID=A0A197BXJ8_9SPHN ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSVMERCKTGKTRLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SMK8_9BACT ----------------KATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIASFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNANIIARISRMVYDA- ->[subseq from] Serine hydrolase n=1 Tax=Chroococcidiopsis sp. CCALA 051 TaxID=869949 RepID=A0A2P8QIE5_9CYAN -------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD -AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI -AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKELAQLMVAVQKGDLISVKSHD -RLLNIMRRTHT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLPSGKRYVAVAMVKR -PHN-NVQAKELIRQVSRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter dokdonensis DSW-74 TaxID=1300349 RepID=A0A1A7BF87_9SPHN ---SFEQRIAELAEPSRGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAATYLEMVE -KGRYSLTSEFPLLLPVRSAFSSARAPVRQGQMPAIDLIEIMITRSSNPATDALLAAVGGP -GVVTDWVHSQGIEQFSINRDIATLVRAIHIDPRDAATPRAMVRLLAGLYRGEFLSDESRR -VLLGAMSRTVTGKRRIVAHMPEEARVSHKTGSLSN-TSSDIGIIESPDGRAIAVAIYVTG -QG-TRLAREERIAAIARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. S-NIH.Pt15_0812 TaxID=1920129 RepID=A0A430BIG2_9SPHN ---ELQARIDSIAAGFRGRFGIAIRAVDDGWTV-EHTARQRLPQQSVSKLWVAMTVLDQRD -QGRVRLDDPIVVRPEDLTLHQPIAFLVKAGGTTVGGLLTRALTQSDNTANDRLLTLVGGP -SAVRRMIQAKRLGEIRFGPGERQLQARYVADPPDGAAPLAIADALARLARGEILSETSTR -ILLDTMASSVTGRARLRAALPPGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD -STRPIRERQMLIQAAAAALTQY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141RLK4_9BACT ------------------------------------------------------------- ---------------------------------------AAALQYSDNTAMNKMISYLGGP -EKVTAFAQSIGDVTFRLDRTEPALNSAIPGDKRDTTTPLAMAESLRKLTLGNALGEQQRA -QLVTWLKGNTTGGQSIRAGLPASWAVGDKTGAGDYGTTNDIAVIWPENHAPLVLVTYFTQ -PQQGAKSRKEVLAAAAKIVTE-- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00099A31FC ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQGFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNSAALLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDESEKIISDIGRATYDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=A0A1H7W616_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLNYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGRAYSIAVFVKD -SEENNQENSKIIADISRIIYEY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella sp. GL-C-18 TaxID=2116704 RepID=A0A2P7QNW1_9SPHN ---ALDMQIRTIGQAFNGDIGIAVEDVQTGWTT-AYDGNTYFPQQSVSKFWVALTALDKAD -RGELSLSRPVTLTKSDMTVHQPVAAQIGPNGTTITALMTRALQQSDNTCNDAVLWRAGGP -DAVRSFLRDKGISGIRFGPGERRLQSKYIASPMDGATPLGIVDALARLKRGELLSPASTD -RLLSIMSNTKTGPQRLKGGLGAGWRLAHKTGTGQQAGYNDIGILTAPDGHSYAVAVMIRR -TSAPLPERMAAMQRTVRSVI--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000B3560F8 ---SLLKEINNITKGKKATVAVSVSGIEDNFQLsNNNGQLKMPMMSVSKFHIALAVLNQAD -KGNLTLDQKILVKKSDLHEWSPIREKYPQGNLPLSEIIYYTVAQSDNNGCDILLRLLGGT -QAVQKFVNSKGIKNIQIKHNEEEMHTKVQVLYENYTTTSSMVKTLKSFYKNMMISKKSTD -FLMDIMLKTDTGMAKLPGLLP-NVKMARKTGSSGTVAENDSGIVTLDNGKHFAIAVFVKN -STESEEINYSIIAQVSKAVFDY- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas laterariae TaxID=861865 RepID=A0A239CY23_9SPHN ---SLERRIVELGRSFSGSVGIAVRDVSDGWTV-GYNADRPMPQQSVSKLWVAMTALDAVD -RGGLSLQEPVTVTRDNLTVHQPVRAMMGPNGTSYGELMRIAMTQSDNTCNDMVLRRAGGP -TAVRSMIERKGLGRIAFGPGETLLQSRYLADPMDGASAEAIAGALARLQRGELLSPASTS -RLLGLMRQSRTGPQRLRGGLAPGWVLAHKTGTGQSTGYNDVGVITAPDGRSYAVAVMIAS -TRQSIPARQQLMNEVVRAVIA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A224A9I1_SHIFL -----------------------------------------------------------SE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- ------------------------ ->[subseq from] Beta-lactamase homolog BlaZm n=5 Tax=Macrococcus TaxID=69965 RepID=B9EC94_MACCJ ---KIKEDIKVIENKYNIQAGVYVNDLTDKQKL-SYNEELLFPYASTFKVINSALLIEKLG ---MNNLDKEVKVSERDIVLYSPIIEKYKNKNVSLKMLIEAALLYSDNTANNLIIEELGGL -KEVEKRLSALGIKGVNVNRKEVALNFYDPKKNEDTISAKNMSKALIKMLTGDVLEYKEQI -FLIDLMKKNKTGTTLIKKGMDKKFIVGDKSGQGNYGVRNDIAVVYKKQSKPIIVVVFTKA -KNEKQKPSDTPIVEISKVI---- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H050 TaxID=1759072 RepID=A0A0W1DT47_9SPHN ----LNDRLYALWRSFPGKTGIAVQRIDGEWAL-AQRGGDLFPQQSVSKLWVAMAVLDAVD -NGRMTLDQRVRIGPEDLVVHQPLASRVQAQGMSVRDLIETAITQSDNLANDSLLRTVGGP -HAVRAFVSRKDLGSIRFGPGERLLQAKYLADPVDGASPSAIASALTRLARGTLLSPQSTD -YLIGVMSRTKSGPKRLKAGLPPGWTFVHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS -TTSSIPARMQLMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0C5XYW9_SPHYB ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L6KSR0_9BACT ---ALKQRLEALVKGKDGRVGICAQD-QSGTMV-CIRGEERFSLQSVVKLIVGAAVLDAAD -RGLADLKAPIVVKPENLSLVQPLAKIVEREGTNADDLVRRAIVDSDSAAVDILIERLGGP -AKVDQFAEGKGILGIRIDRDERHLQTAYQKDPRDTATPRAMTAFLAALMNGKLLAAGSTQ -RLLAIMGETVTFPDRLRAGTGEGWSVAHKTGTSRNAATNDVGILTAPDGGKIAVAVFVAD -SRETPTQRSAIIAGAAQAVTEAy ->[subseq from] Beta-lactamase n=3 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A5M6AF75_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI -DQVNEYVKSLGIKDCNLAATETLMHTS-GDTDLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A3G2C7C6_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDVDNAAIIASISKIVYDT- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium RIFCSPHIGHO2_01_FULL_65_20 TaxID=1802169 RepID=A0A1G3JUE2_9SPHN ---GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD -RGELTLDQQVTITPDDLTLHQPLAARVSREGETVRSLINEALTASDNSANDALLRTAGGP -AAVQDFLRRKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPARMQLMQAVSRAV---- ->[subseq from] LRA-5 n=1 Tax=uncultured bacterium BLR5 TaxID=506522 RepID=B5L5W7_9BACT ----LTERLSSIINAAGGDIGIAVIHVETGHTT-AIQGTTQLPLYSVFKLPLAIAVLKEIE -ENRLQLDRKVRVTPADVAPTANAAMWRRPIDRTVAQLIEVSIIRSDNTSSDKLLQLVGGP -AAVTHRMRALGFPNIEIVSTVREFSEN--RTRPNTGSAEDLARLLVQLQKGELLQPQHSA -LLLGFMHRATTGTERLRGSLPVGTPVADKTGTGDAGVTNDVGIITLPKGGHLAIAVLISG -SKLSPAAQEKLIAEIARAAYDA- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium fuliginis ATCC 27551 TaxID=1208342 RepID=A0A5B8CM55_SPHSA ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aestiaquae TaxID=1509367 RepID=UPI00136E2408 ---DFEKRIAQIADGGKGRIGVAAIDLATGKQV-SVLGDQRFPMASTSKVAIAAVFMAGVD -QGRWSLTSEYALLRPVRSAYSSKRAPVRKGEISAREHLDLMISKSCNACTDTLLRVVGGP -AAVNAWMRSVGIEGFELSRDIATLVRATVIDTRDSATPLAMARLLAGIYQGEWHSKYSRD -IIIGAMERTTTGKKRMRSGLPLSANVAHKTGTLNR-TASDIGIFQTPDGRTIAAAIYVTG -QSASRRMRDERIAQIARALYNGy ->[subseq from] class A beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 150272 TaxID=2016504 RepID=UPI000B96B17C -----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT -PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP -DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR -RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS -PRPDTERVNEIFAILAREAL--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. SA916 TaxID=1851207 RepID=A0A2K0XTM1_9SPHN ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Blastomonas natatoria TaxID=34015 RepID=A0A2V3UVL4_9SPHN ---GLRDELQELWRTFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMTVLEKVD -RGELALDQEVTITPDDLTLHQPLAARVAREGETVRSLINEALTASDNSANDALLRTAGGP -GAVNDFLRRKGLSNIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQASTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPARMQLMQAVSRAV---- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. SCN 67-18 TaxID=1660141 RepID=A0A1E4JFD2_9SPHN -----NREIGRLGAGFDGRAGIAVLDIDAGWSA-SFNGDQPMPQQSVSKLWVAVAALDALD -RGAMRLNDPVTVTRADLTLHQPIRANVGAGGTTIGALLNQAMTRSDNTANDMLLWKVGGP -EAVRGLLMDRGVRGVRFGPGERLLQSAYLDDPMDGATPLGIVDGLAKLQRGRLLSPASTR -LLINTMTESRTGPQRLKAGLGAGWTAAHKTGTGQATGYNDVAIITSPNGHSYAVAVMIAS -TRQSIPVRQKLMADVVRAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Legionella sp. km772 TaxID=2498111 RepID=A0A3S0VWY9_9GAMM --kDLDKKIKAIEKKNNTIIGLTAIHIENNTKI-AHNNTQRFFMASTIKVPIALAFLHRVD -EKKESLNRVIKMDTKNSVPGSGSLYHIFEKKMSTQQILKHMLINSDNSASDTILHAANGP -KYVTQYMANLGFKNIVVNRSILEMFLKFQNDKRDTTTSDEMAKLLVKLQKNQILSESSTQ -LVLKIMQDCRTGRSRIRGLLPGGVKVAHKTGTWAPGFASDVGIITLPNNGHVAIAVYVKS -KSASDYPRSRSIALASRAIYDYf ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. SG720 TaxID=2586998 RepID=UPI001448689A ---AIQQRVAAIAAAARGRVGVAAMDLDGGGQV-LINGDMPFPMASTAKVAVAATFLQMVE -QGRFRLDQQLPMMMPVPEPRNLVAMVRPGPVYTAQTLLERMITRSDNHATDGLIAAVGGI -GAVNRFLVQTGISGQHLDHTMATLVRARAIDTGTSSTPRAMIALLSAIDRGGALSPQARA -VLLDTMTRTSTGKNRIRAGLPEGVLLAHKTGTLA-GVTDDVGIVRMPDGRHLAMAIFVAG -PE-NHTAQAGMISRIAATLYEGf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A412YPK6_9BACE --qTLESKIGDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN -KQETPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHIHQYINKLGVCDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD -FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMAYDEy ->[subseq from] Beta-lactamase n=1 Tax=Coprobacter secundus TaxID=1501392 RepID=A0A0B2JH50_9BACT --nELRKELEAVIRDKKARVGVAVIY-DGKDTL-TLNNEYRYPMMSVFKFHQALSVLNDLD -SGGLPLDTEIFVKKSDLHPYSPLRDSVPQGNMTVAELLRYSITLSDNNACDILFKHFGGT -GKTEKYMKGLGIEKIVIQFDENEMHTSVDAERANWTTPLEAAKVMDIFLRNKLFSVSLSD -FLENLLICTSTGADKIKGGLPSGVIMGHKTGSSSRTADNDLAFVQLPDGKRYTIAVFVMD -ADEDDKTIAGIISQISRHVYDFy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacteriaceae bacterium DW12 TaxID=1550091 RepID=UPI00053251BB -----NIQVDSILRDKKAHIGVHILHLKDGVEL-QVNGENTFPMQSVFKFPIALAVLDMLQ -QKQLPLDHGIYVAKKDLLLWSPLRDQYPEGNLPISKLLAVMVSQSDNNACDILLRWIGGE -DVVQRYIQKLGISDMKIVANEEAMHRDWNVQYLNYSSPKSSNELLVKAYKSNLLSPQYLD -FFWKVMTETSTGKKRITAPLPKGSIVSHKTGSSGTGAVNDVGIVQLADGTAYAISVFVVN -SLEDESTNEQIIAAVSQITYL-- ->[subseq from] Beta-lactamase n=1 Tax=Legionella santicrucis TaxID=45074 RepID=A0A0W0Z3Q9_9GAMM ---ELSKRINAIEKNSRTVMGVTAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKESLDRVIKMDTKNSVPGSGTLHYLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDMRDTTTSDDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] Class A beta-lactamase n=1 Tax=Novosphingobium sp. FSY-9 TaxID=1908524 RepID=A0A3S2Y7A0_9SPHN --------------------------------L-GFWQHQRFAFCSSFKLSLAALVLDGAE -KGEWRLEEKLAYSAADLLPNSPVTQANLALGMTIEALAEAAQKFSDNAAANILLRKIGGF -DRLNQFWWGLGDTVSRLDDYETALNRVPLGSVRNSTTPAAMALNLVKLFYQGALSPAAAA -KLKGWMHDTATGAKRLRAGLPADWWAGDKTGTGLRGTYVDLAWVEPPKLPPFAIAAFYQP -PKPTDPNAEAILAEVGRMVA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis fribergensis TaxID=1515612 RepID=A0A0A7PJX3_9SPHN ----LNDRIYELWRSFPGKTGIAVQRIDGEWAL-SQRGGDLFPQQSVSKLWVTLAVLDAVD -QGRMTLDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -NAVRAFIAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQDVMSRTRSGPRRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGT -TTSSIPARMALMQSVSSAVAEY- ->[subseq from] Serine hydrolase n=1 Tax=Thermosynechococcus sp. CL-1 TaxID=2583530 RepID=A0A5C2M772_9CYAN ---NLQQQIQQLVSRQNLAAGLYFFNLDSGASL-NVGGDAVFPAASTIKFPILVAFFKAVD -EGRVTLHERLTMRPDLIASEAGTLQQKPNSQYPALEVADLMITISDNTATNMIIDRLGGA -AVLNQQFQEWGLENTVINNLLPDMKGT------NTTSPRDLATLMLKIGQGEIVSPRSRD -RLLDIMRRTVT-NTLLPAGLGKGATIAHKTGDIGI-VVGDVGMVDMPNGQRYVAAMMVKR -PYND-PRGSELIRQVSRMAYQAf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. MM-1 TaxID=745310 RepID=M4SBW5_9SPHN ----LEARIATLGQSFAGSVGIAVRDVSTGWAV-SYNAQRPMPQQSVSKLWVSMAVLDAVD -RGTISLSEPVTVRRDNLTVHQPVRAMMGANGTTYGALMRIALTQSDNTCNDMLLRRVGGP -DAVRGMILRKGLGRIAFGPGETLLQSRYLADPMDGATAEAIAGALARLKRGELLSPASTR -LLLTTMGDSRTGPQRLRAGLAPGWTLAHKTGTGQATGYNDVGVITAPDGRSYAVAVMIAS -TRQPIPVRQRLMADVVRAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-4101 TaxID=2005461 RepID=A0A1Z4QVM8_9CYAN ---TLRTSIQSLAAASNLTPGVFIADLDTGSYV-DFNGGAMFSAASTIKIPILVAFFQDVD -AGKIRLDETIASTKTTIATGSGIQYKPVGTSYSALEIATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLNTTVIRNPLPDIEGT------NTATPKELAHLIAVVTKGNLVSMQSRD -RILDIMRRTVK-DNLLPAGLSDGATIAHKTGEIG-AILADVGLVDLPTGKRYIAAVMIQR -PRND-ASAEKLISSISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas fennica TaxID=114404 RepID=A0A2T4HQ24_9SPHN ----LEARIATLGQSFAGSVGIAVRDVSTGWAV-SYNAQRPMPQQSVSKLWVSMAVLDAVD -RGTISLSEPVTVRRDNLTVHQPVRAMMGANGTTYGALMRIALTQSDNTCNDMLLRRVGGP -DAVRGMILRKGLGRIAFGPGETLLQSRYLADPMDGATAEAIAGALARLKRGELLSPASTR -LLLTTMGDSRTGPQRLRAGLAPGWTLAHKTGTGQATGYNDVGVITAPDGRSYAVAVMIAS -TRQPIPVRQRLMADVVRAVVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=C3VJU8_STAAU -------ELNDLEKKYNAHIGVYALDAKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTATNKIIKEIGGI -KKVKQRLKELGDKVTNPGRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQA--------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. H038 TaxID=1759066 RepID=A0A0W1EQP5_9SPHN ----LNERIYELWRAFPGKTGIAVQRIDGEWSL-SQRGGELFPQQSVSKLWVALAVLDAVD -QGRMTMDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -AAVRAFIAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TSSGIPARMALMQSVSSAVAEY- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. B(2019) TaxID=2690446 RepID=UPI0013914311 -----KNAVQNLAANSDLTPGAFLVDLDTGAYV-DVNGSASFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQEMIAGGSGNLQYKPAGTYSALEVATKMITISDNTATNMLIAHLGGR -EVLNQRFRSWGLTTTTIRNLLPDLQGT------NTTSPKELGNLIAIVNQGNLVSMRSRD -QILDIMRRTEK-DNLLPSGLGAGARIYHKTGDIGT-MLADAGLVDIPTGKRYIAAVMVQR -PNND-PRAEKLISSISRSAYEQf ->[subseq from] Class A beta-lactamase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A5C8DCP7_9BACT ---SLRVNINRIAQRINARVGVSISLIEAGDSL-SYRGEERFPMMSVYKFPIAIAVLKELD -RGTTFMERYLLLPKDSIYTGEEETYSFPGGKITIGQLLTLMLVQSSNTACDQLLYLLKGP -ANMQPYLNDLDIQDMAIANTEKEINIDSLLRFDNWSTPDEMRGLLAIAYTGDYLSKKNHD -FLWDKMTETVVGANRIKGLLPKNTVVAHRTGTGY-GSYNDAGIITLPSGKHLAIVVFISE -AQENPEKCNEAIARIAKLAWDYy ->[subseq from] Beta-lactamase class A n=2 Tax=Microcoleus sp. PCC 7113 TaxID=1173027 RepID=K9WCY8_9CYAN ----LKSQIQTLAANNKLQPGVFIVDINTGTYI-DINSRSPVPAASTIKVPILVALFKEVD -EGKIRLDESLTLQSEMIATGSGNLQQKPGAKFTVLELATKMITISDNTATNMLIARLGGI -EALNQRFRAWGLTTTVLRNALPDLEGT------NTASPQELAALMAMINQGQLVSLPSRD -RILSIMQSNEI-NSLLPQGLGSGAIIAHKTGNIG-ALLADVGLVNMPSGKSYIISVMVQR -PFND-DSAQELIRKISKTAYEYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=A0A2L0NG86_STAHA ------------------------------RILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SGA7_9BACT --nELRKELEAVIRDKKARVGVAVIY-DGKDTL-TLNNEYRYPMMSVFKFHQALSVLNDLD -SGGLPLDTEIFVKKSDLHPYSPLRDSVPQGNMTVAELLRYSITLSDNNACDILFKHFGGT -GKTEKYMKGLGIEKIVIQFDENEMHTSVDAERANWTTPLEAAKVMDIFLRNKLFSVSLSD -FLENLLICTSTGADKIKGGLPSGVIMGHKTGSSSRTADNDLAFVQLPDGKRYTIAVFVMD -ADEDDKTIAGIISQISRHVYDFy ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542Q6H5_9BACL ----WQQAVENVLKEAPGIYGIAAVHLETGETV-GHLDEELFQLASTFKIPIMVTLMREVE -AGQIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWVLLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVND-VVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Chroococcidiopsis sp. TS-821 TaxID=1378066 RepID=A0A2S6V5K6_9CYAN ---SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASTIKVPILVAFFQDVD -AGKIRLDERLTLKKELVGGGSGDMQKPLGTQFTALETATKMITISDNTATNLLIERMGGA -AALNQRFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAHLMALVDDGKLMSLRSRD -RLLDIMRRTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPNGKRYIAVAMVKR -PHND-GRAQELIRQISRAAYQE- ->[subseq from] Beta-lactamase n=2 Tax=Legionella shakespearei TaxID=45075 RepID=A0A0W0YKX7_9GAMM ---DLAKKISAIEKKANVIIGITAVLIEKNKVM-SHNGNKRFFMASTIKLPIAIAFLHRVD -EKKDSLKRIIKLDYNNSVPGSGSLYHIFEKKMSSQQIMNHMLINSDNSASDTLLDAVNGP -QYVNKRMSALGFKNISVNRSILEMFMRFEKDARDSTTPDDMANLLVKLYNGEALSESSTD -LLIKTMEKCRTGRSRIKGLLPPNVKVAHKTGTWAYRFASDVGIITLPNKGHIALAIYVKS -QSASDYPRSHSIALASKAVYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas asaccharolytica TaxID=40681 RepID=UPI0008357497 -----TALVPSLTRDFGGKVGIAVMSIDDGWTV-TSNGDMKLPQQSVSKLWVAMTVLDLRD -QGKLTLDDPYTVRKDDLTLHQPIAALVKDDGTTVGELLQRALTQSDNTANDCLLRLAGGP -TAVRAFLTKKGISDIRFGPGERLLQSRYVADPPDGAAPRAIVTALARLKKGELLSPTSTQ -YLMSTMESSRTGRQRLRGAVPEGWTFGHKTGTGQTAGYNDVGFLISPNGKAYAIAVMIGD -TPKTIPERQQLMQAVV------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=F1DI11_ECOLX ------------------------------------------------------------- -AQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLSHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTN--------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella sp. YJ22 TaxID=1104780 RepID=UPI00140D601B --sALEERVQELGHSFPGEVGIAVRDIETGYVA-SWNGGRLFPQQSVSKFWVSLTTLDAVD -RGRLDLDRRVTVTRDDLTLSQPIAQQVDADGTTLRDLMTRAITRSDNTANDFLLWQAGGP -EAVRAFISRTGIEGVRFGPGERLLQSDYIEDPQDGASPLGLTQGLAMLQRGELLSPASTR -HMISTLRATRTGPNRLAGGLAPGWTIGHKTGTGQQAGYNDIGIITSPDGRHYALAVMIGR -VSVPLGVRMTLMNNVTRAAIQY- ->[subseq from] uncharacterized protein LOC115123033 n=1 Tax=Oncorhynchus nerka TaxID=8023 RepID=UPI0011312053 ----AAAALADLERDAGGRLGVCAIDTASGRII-EHRSGERFPFCSTFKAMLSAAVLAQSV -DRPGLLQQRVTYTKADLVNYSPVSEKHVGVGMTVAALCEATIQYSDNSAANLLMKLIGGP -SAVTAYARSIGDDTFRLDRWETELNTALPGDLRDTTTPAAMAASMR-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Legionella sp. 13.8642 TaxID=2259147 RepID=UPI000E205FA1 ---ELSQRINAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=A0A1T3FLP1_ELIME --nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE -KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT -DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK -WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD -TYENFNDSEAIIADIAKTVYDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Edaphobacter aggregans TaxID=570835 RepID=A0A428MMG1_9BACT ---PLRQQIRSIAAEAHGKVSVACSLPGSSLNC-DLDPTAQPPMQSVFKLPLALAILHQVE -QGKFSLDQPIRFLREDLILYSPLQDKYPDAGVPLRTLLQLTVSLSDNTAADILLRLAGGT -KVVDEYIASLGITGFHLEDGERALHRQVALQYRNWFEPQGAVQLLRRISDHSPLTAEHTE -LLLGWMRPAVP-TKRLEGDLPKGTSVAHKSGTSDAHATNDIGLIAMPDGRQLAIAVFVTD -STADQATREKVIAEIGRAAYD-- ->[subseq from] HGG-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C144_9ZZZZ ---DLTSDIQEVIKGKKAQVGVAVLY--KDDAF-TANSDDQYPLMSVFQFHIALAVLKKME -KEGIPLTAVVTLGPSDIDTWSPMYKKYKSKKLSYGDLINYMVSQSDNNACNWLINFVGGI -QNVNDFIKNLGIDRIQLIETEKSMEQDIRKSYNNWSTPLSVTQLLRKVYTEKVLSDEHFA -FLEKAMLASASGKDKFRAGLPKEVEVGHKTGMSYRTCDADVGVIYMPGGEKCYLAVLVKD -SKETDAANAKIMADIAKKVYSHy ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium haifense DSM 19056 TaxID=1450526 RepID=A0A246BAJ8_9FLAO --aELKKEISKITEGKKATVAVSVKGIDFPFEFnNENLRKKLPLLSVFKFHIALATLDMVD -KGRLNLNQKIFIKKEDLHEWSPLREKFPNGNMTLSELLKYMVANSDNNATDKILNVIGGT -QIVQNFIDSKKIKDFQIRVNEERMNSAWKSMYENWSTTESLVKSLIKFDKAKILPKTSRD -LLMNIMLGTTTGTNKIVEQLPKGTPVAHRTGSSGTVAENDIAIITLPNGKKYAIAVLVSD -SRESYEVNCKMISDISKTVWNH- ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia sp. 2-6 TaxID=2575699 RepID=A0A4V1DZD6_9FLAO ----LKKTLESIISGKKSTVGVSIMDPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMHQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAIFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium PASS1 TaxID=2015579 RepID=A0A257DH12_9SPHN -----ENLIQDQWRLFPGRTGVAIMRVDGGEWVlGRRMDELFPQQSVSKTWVALTVLDMVD -QGKLRLDQKVRITRDDLAVHQPIRDQVIANGVSVLNLLEQAIRASDNTANDSLLRTVGGP -QAVTSFIVRKNLGAIRFGPGERALQSRYLNDPIDGASPQAIVRALARLAKGELLSASSTR -LMLDIMSRTSSGPNRLKAGVPAGWSFLHKTGTGQSTGYNDIGIMTAPDGTRYAVAVMMGS -TTASIPQRMTFMQFVSRAVASY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=A0A0D5BL05_ELIMR -htSILNDINAVTKDKKATVAVSVLGIENEFQFsNNNGNLKMPMLSVFKFHIALAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -RTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGMFLSKRSTI -FLMDIMTRTNTGMAKLPGLLP-KVKMARKTGSSGKMAENDSGIVTLVNGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A0D5CA60_KLEPN -----------------------------------------------------AAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGS---------------------------- ------------------------ ->[subseq from] Beta-lactamase n=3 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SFD7_9BACT --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGTKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQENDADNATIIASISKIVYDT- ->[subseq from] Class A beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q3VHP6_9BACT ---NLAAEIQKIEASLGARIGVAAQRF-GGARF-DYRGAERFPLQSVFKYPLAVAVLRAVD -VGKLKLDGAVILDRSNLSVYSPLGETVLAKGTTWAELVKRAVSKSDNTAADVLMRRIGGP -STLTATLRSLGVTGVRIDRYESRLQCRALAEVRDTSTPNGMLTFLRGYDTGGWLSALSKN -FLDRTLFETMTGPDRLRAGFGPDWKLRHKTGTGGYGARNDVGIATAKDGSKIAIAVFLTG -ASGRDKVRDAAIAKVTRLVRD-- ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-7 TaxID=2013670 RepID=A0A2N3B5C3_9PROT ---SFEQRIAELANADQGRIGVAAIDLATGEEI-MVLGDQLFPLASTSKIAIGAAYLEMVE -QGRYSLTSEFPLMMAVRSASSPKAPVREGQYMPAIDLIEIMITRSSNPATDAMLAAIGGP -AVVNDWVRRQGINDFSINRDIATLVRANHIDPRDAATPRAMVRLLAGLYRGEFLSDQSRQ -VLLGAMSRTITGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG -QG-TRLAREQRIAAIARALYDGf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A292ZJK4_SPHSA ------------------------------------------------------------- -----------------------------GRPLPVRTLIDMSLTLSDNEATDALVARAGGP -QAVNDWVRAAGIRGLRVDSNTRDLLAGFAADPRDTATPRAMDDLLAAIRLGRVLRPQTTA -LMLSVMERCKTGKARLRAMLPPGTRIAHKTGTLN-GLGNDAGIVTLPDGRMFVISVFVMK -DHMGHELRDRIMAEAARAAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Legionella steelei TaxID=947033 RepID=A0A0W0ZRM3_9GAMM ---ELIRKLNVIEKKSNTIMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -EKKDSLNRVIKMDARNSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -KYVAQRMSALGFNNIFINRSIMEMFVRFENDTRDTTTPNDMAKLLVKLYKKQALSESSTN -LLMKIMEQCRTGRSRIRGLLPPSVKVAHKTGTWSYRFVSDVGIITLPNNGHIAIAVYVKS -KSASDYPRSHAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000C9AADFE ----LKKTLESIISGKRATVGISIMGPNTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MKH4_9BACL ----WQQAVENVLKEAPGVFGIAAVHLETGETA-GHLEEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Beta-lactamase TEM n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BNE8_KLEPN ------------------------------------------------------------- --------------------------------MTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFAQ-HGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Uncharacterized protein n=2 Tax=Sphingobium quisquiliarum TaxID=538379 RepID=T0H4G6_9SPHN ----LLGEFERFAALTDGTVGIAVRDLHSGQSI-GINNDTLFPMASTYKVAVAGKIFSMAD -AGALNLDERLP---------------RLGTPLPVTALLELMLTRSDNEATDVLVARAGGP -QAVNSWLQSIGIHGQRVDSNTAQLLEAFAADPRDTSTPRAMNDLLAAIHHGKALKPGSSA -ALLAIMARCKTGKARLTGMLPPGTQIAHKTGTLN-GLGNDAGLIALPDGRTFAISVFVMK -DHRGHVLRDRIMAEVARAAYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. ZJ709 TaxID=2709797 RepID=UPI0013EDBDEF ----LRHNIQKIIENKQATIGVGLI-VDGKDTL-TINNNHNYPTLSVYKFHLALAVLNYMQ -INNISLEHEIFIAKDDLLPHSPLRDTNPDGNMSIADLIKYSVAKSDNNACDILFKYIGGT -TKVDQYIKSIGIENCHIAATEAKMHEQFENQYLNWSSPLSAVRLLEVFRSNKLLSPIYQD -FLWKTMVETTTGSNKIKSLLPAKTLVAHKTGSSFRNAENDIAIIQLPDGKYYSLAVFITD -SMENDDINAKIIADISKTVYDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Thalassocella subtropicalis TaxID=1123952 RepID=A0A2L0NG97_9RHIZ ------------------------------KILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDKRDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI0009990A4C ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA -YLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD -SMESEEVNCGMIAQISKVVWDA- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000C6C8F22 ----LKKTLESIISGKRATVGISIMGPNTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingosinicella sp. BN140058 TaxID=1892855 RepID=A0A4P6FKG4_9SPHN --rALDAQIRAIGNTFNGDIGIAVKDVQTGWRT-AFDGNTYFPQQSVSKFWVALTALDKAD -RGELSLTRPVTLTKSDITLHQPVAAQIGPSGTTITSLMTRALQQSDNTCNDAVLWRAGGP -EAVRAFLRNKGISGIRFGPGERLLQSKYIASPMDGATPLGIVDALARLKRGELLSPASTD -RLLSIMSNTKTGPQRLKGGLGAGWRLAHKTGTGQQAGYNDIGILTAPDGHSYAVAVMIRR -TSAPLAERMAAMQRTVRSVI--- ->[subseq from] Beta-lactamase n=1 Tax=Legionella parisiensis TaxID=45071 RepID=A0A1E5JRV6_9GAMM ---ELIKKIRDIERKSNTVMGITAIYIEKNKVI-AHNSNQRFFMASTIKLPIAMAFLHRVD -ENKDSLNRVIKMDSRYSVPGSGALHYLFEKKISLKQILMHTLKNSDNSASDALLQAANGP -RYVAKRMNALGFKNIFINRSIMEMFIRFEKDIRDTTTPNDMAKLLVKLYKKQALSQSSTD -LLMKIMEQCRTGRSRIKGLLPANVKVAHKTGTWSYRFVSDVGIITLPNKGHVAIAVYVKS -KSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0004E3CA50 ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYSTLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter sp. YJ20 TaxID=1104773 RepID=UPI00140C5D14 --tALERQVAQLTANAKGRIGVAAIDLTTGKQV-SVLGTQRFPLASTSKIAIAATFLEGVD -QGRWRLDDKFPMML------SPTQ---EGRSLSARELIELAITRSSNEAADGLLRVVGGP -RAVNDWVHRAGIREFSIDRYIDTLVRAQSIDVRDSATPLAMVNLVKGLHDGRWLSQSSRN -VLLGAMGRCKTGPQRIPGQMPDGVMVAHKTGSLYN-TSSDVGIVTGPDGHAIALAIYVTG -GRNDHKYRFEKIGTIARVVYDGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A7U967_ECOLX -------------------------------------------------VMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKT------------------------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas panacis TaxID=1560345 RepID=A0A1B3ZG99_9SPHN ---ALARSINAVARSFDGRVGVAVRSIDKGWTV-ESNGDVRLPQQSVSKLWVAMTVLDLRD -SGRLTLDDPITLTRNDLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP -SAVRDFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKDELLSPNSTA -FLISTMESSKTGKQRMRGAVPVGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD -TPRTIPQRQELMQSVVQAVVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas formosensis TaxID=861534 RepID=UPI0012F99B1E ---ALANRITTLGRSFNGLVGIAVRDVQTGWTA-SYNGSLLFPQQSVSKLWVSITVMDAVD -RGRLRLDQPVTIRRDDLTVHQPIRALVGPDGTTLGALIEQAMTRSDNTANDKLLWTVGGP -EAVRSMLARNGISGVRFGPGERLLQSRYLADPIDGASPEGITLGLAGLARGNLLSPASCR -YLLGVMENSKTGPQRMRAGLAPGWTLAHKTGTGQATGYNDVGLVTAPDGRAYAIAVMIGR -TTLTIPQRQRLMSDVVRAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG1_02_56_21 TaxID=1805132 RepID=A0A1J4SWN4_9BACT ---AMVSSLGKISRAYKGRVGIYIKDIETGKTW-SYNADRLFPSASLVKVPIMAAVFEKIQ -TGSMTLDTQIKLTRQKRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATRMLIDSV-GM -PYLSESFRKMGLEHTNITPEGMSLTSG-RVVRENYTTASEMAYLMEQVYEGKLVSRESSE -FMLDVLKHNKS-RSRLRRGLPLGWEIGHKTGLLRK-ACHDVGIVFSPRGD-YVIAVLTSE -VP-NYSSAKNFITRVAKLTFRYy ->[subseq from] class A beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013D7A789 ------------------------------------------------------------- ---------------------------------------RAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARLALE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides thetaiotaomicron dnLKV9 TaxID=1235785 RepID=R9HGM1_BACT4 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVIIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=UPI00102A0948 ---ALKQRLEALVQGKDGRVGICAQD-QKGTAV-CVRGEERFSLQSVVKLIAGAAVFDAAD -RGLTDLKEPIVVKPENLSLVQPLAKIVEREGTNADDLVRRAIVDSDSAAVDILIERLGGP -AKVDQFAEGKGILGIRVDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLLSTGSTQ -KLLAIMAETVTFPDRLRAGTGEGWAVAHKTGTSRNVATNDVGILTAPDGGKIAVAVFVAD -SRETPTQRSAIIAGAAQAVTEAy ->[subseq from] serine hydrolase n=1 Tax=Oscillatoria sp. PCC 10802 TaxID=1173028 RepID=UPI0012DBF771 ---DLKMQLQALAAQNDLAAGAFFADLDTGAYI-DLNGSQALPAASTIKLPILIAFFQDVD -AGKISLEEPLTLREEDIAEGSGDMQDNPGRSYTALETATKMIAISDNTATNMLIERLGGA -ETLNQRFASWGLTETAIRNKLPDLEGT------NTTSPKDLGNLMAQVNQGELVSLRSRD -RLLGIMQRTEN-NTLLPQGLGEGATIAHKTGTIAS-MLGDAGIVDLPTGKRYIAAVMVKR -PDND-PRAEELIRQFSRKVYLYf ->[subseq from] Beta-lactamase n=2 Tax=Propionibacteriaceae TaxID=31957 RepID=A0A2A9GWF6_9ACTN -------LIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT -PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP -DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR -RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS -PRPDTERVNEIFAILAREAL--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KZQ1_9BACT ------AAIREIVRPLKAKVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD -QEVLNLDQKLHVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP -AAVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPSAVTFLFRMFDEGKILKKDTQL -FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN -SKDSPAVCEGTIASVARWLCTEw ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI000D6509AA ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DAVNQYIHSLGVTDCAIVCTENEMHQDESLCYQNWTTPLAAARLLEIFRKEVLFPQEYKD -FIYQTMTECQTGQDRLVALLDKKVTIGHKTGTGDRNACNDIGFVLLPDGHVYSIAVFVKD -SAENNQENSKIIADISRIVYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000B34B5CB --nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE -KGELKMSQKIFIKKEELLDWSPFLQKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT -DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK -WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD -TYENFNDSEAIIADIAKTVYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0009BDCC0D ---HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0013205530 ---HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Cyanobacteria TaxID=1117 RepID=K9TXP2_CHRTP -------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD -AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI -AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKDLAQLMVAVQKGDLISVKSRD -RLLNIMRRTQT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLLSGKRYVAVAMVKR -PHN-NVQAKELIRQVSRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Legionella cincinnatiensis TaxID=28085 RepID=A0A378IMT0_9GAMM ---ELSKKIKAIEKNSHTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKDSLDRVIKMDTKNSVPGSGTLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTN -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYEHf ->[subseq from] serine hydrolase n=1 Tax=Chroococcidiopsis cubana TaxID=171392 RepID=UPI000D04BE3A -------------NNTQLFPGMFFIDTETGTYL-NWNGDTTFAAASTIKFPILVAFFQDVD -AGKIRLDEKLTLKKELVGGGAGFQYKPLGSQFTALETATQMIIVSDNTATNLLIERLGGI -AALNQRFKNWGLTVTELRNLLPDLEGT------NTTSPKDLAQLMVAVQKGDLISVKSRD -RLLNIMRRTQT-ATLLPKGLGPGATIAHKTGDIGS-MVGDVGLVDLLSGKRYVAVAMVKR -PHN-NVQAKELIRQVSRAAYQEf ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium sp. SG707 TaxID=2586996 RepID=UPI001447E78F ----------DIERQYGGRLGFAVA-FSSGGIV-NWRGHERFAFCSSFKLSLAALVLTGAE -KGEWRLDEKLPFGKGEVLFNSPALQARLGLGISMAEAAEAVQKQSDNGAANLLMRRMGGF -DRVNRFWRGLGDMVSRLDDYETALNRVPPGSLRNTTTPEAMADNLFRMFRQGALSPAVVT -RLKGWMHDTTTGAKRLRAGLPGNWWAGDKTGTGLPGTYVDLAWVEPPDLAPFAIAAFYQP -PKPTDSNAETVLAQVGQNIAQ-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI000E5D3AD0 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGEIDIADLLNYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAVFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1Q1S3_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=3 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=K9DEM1_SPHYA ---HLLAEFDRFAALSDGTVGVAVQDLQTGEIQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium kunshanense TaxID=1445034 RepID=A0A328BLJ7_9CAUL ---ALQSRLDALAADYGEEVGIAVTDVQAGWTA-GVDRDRPYPQQSVSKLWVAIAVMKAAD -EGRLDPEAPLTLTEADRSVFQPVSYKIGPAGTPLSDLLRRALVESDNAANDRLMRELGGP -EGVAATLDEMGLTAVKVGAYERDLQAAYLADPPDGTTPAAITAALAALHRGELLSAASTQ -RLIGLMEQARTGPRRLKGGLPPGWTIAHKTGTGQSVGINDVGLLTAPDGRTYAVAVMLRH -TRQPVPARLAFMQSVTRTVAEHw ->[subseq from] Beta-lactamase n=1 Tax=Legionella sainthelensi TaxID=28087 RepID=A0A3S4HK61_9GAMM ---ELSQRINAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Microcoleus vaginatus FGP-2 TaxID=756067 RepID=F5UQ40_9CYAN ------PQIESAIEQYSLSAGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFYQDVD -AGKVSLDETLVMKSDLVASGSGTMQDRPNGTFSIRETVDKMITISDNTATNMIIERLGGI -AKLNERFRSWGLTDTRIRNWLGDFQGT------NTTSSVDMVKLLAMLSRDKLVSESSRE -QALELLRNTTT-RTLLPSGLGPGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR -PYND-PIVRDFVRRISRIVYNY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus equorum TaxID=246432 RepID=UPI000FF868FE ------------------------------------------------------------- ------------------------------------ELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A291N1Y8_SPHYA ---HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLRLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=A0A1Q9SHU1_9ACTN ------DELARRASASGGRLGLAVHDLGTGERA-EVDAGRVFTAASVIKLPIMMTLLSGTE -AGTWSLDDRLPLAPSRRVGGAGVAAELADVPLSVRDLLTLMIIVSDNMATNLLIDLL-GM -DAVTSWCARHGMPRTVLARSMMDADAR-ARGHENRTTPADTAALLTGLARGDLLGERATA -HALEVLTRQQT-ADRLPRHLPGGVRLAHKTGELD-GVRHDAGIVLADGRAPIVIVVLTEG -FA-DEDHAADLVAEAGRVVYT-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6WXL8_9SPHN ---HLLAEFDRFAALSDGTVGVAVQDLQTGEIQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLRLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Akkermansia glycaniphila TaxID=1679444 RepID=A0A1C7PCU8_9BACT -------GLEKAVRLSDGKVGFFVLDLDSGASA-GWGDEGMYPMMSVFKFPLALSVLSRVD -EGKLDLDAKYRVAGKDLDPWSPMREKFPQGGFTLRELLRYSVAESDNNACDFLFGLIGGP -AAAQADLKKWGVEDISIRVLEGVMQDDWNAIYLNAARPSAMAGLLKLFADGKILREATNR -ELWEMMAGCKTGTDRLVQGMPAGAVLAHKTGSSGVGAFNDVGIAVLPDGRRLAICAFVSD -SRRPVKECAAVIASLARWACSEw ->[subseq from] Uncharacterized protein n=3 Tax=unclassified Cyanobacteria (miscellaneous) TaxID=1983111 RepID=A0A3B8JK67_9CYAN ----LKAKIQTLVAQYQLQAGVFLLDLETRAYL-DLNSDSTFASASTIKLPILIALFQDVE -AGKVRLDESLTLKSEMRVGGSGDLQKKPGTQYILLEVAKKMIAISDNTATNMLIERLGGI -EALDQRFHSWGLTTTVLRNVLPDLEGT------NTTSPKELANLMLMVNQGRLVSERSRD -RIIDIMQQTQT-NTLLPKGLGVGATIAHKTGTLGS-LLADIGMVDLLTGKRYIVSVMVKR -PHND-AAAEELIRQISRTTYDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KJI0_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter splanchnicus TaxID=28118 RepID=UPI000D90A6BC ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=A0A127SZ44_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZN7_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Odoribacter splanchnicus TaxID=28118 RepID=A0A412WI85_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GNPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Moorea producens PAL-8-15-08-1 TaxID=1458985 RepID=A0A1D8TW64_9CYAN ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVANKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFHLEQGKWISPQSRT -DLINIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQAYDYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X220_9BACT ---ELTKRLATLAKSIGDDVGVTVIHVETGRTI-TVDGAKKLQLYSVFKVPLAIAVLKAVE -EKKISLEQKLHVTPSDVAPGSQINTDLWRRPKNVAELLEFSIVRSDNTSSDKLMQLIGGP -AVVTERMRALGYSNIDIVTTVRDFAA--KGENPNVGTPADLARLLTQLQKGELLQPANAS -LLLGYMERARTGERRLRANLPAGTQVAEKTGSGT-AATNDIGLITLPDGGHLAIAVLING -TKSKTDAQEKLIAETARAAYDAf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Rhodanobacter TaxID=2621553 RepID=A0A1E4Q6S9_9GAMM ---VLQGKLEALARRAPGVLGITVLDPQSGERW-RVNAERAYPMMSVFKAPVAAAVLARID -SGTLTMHETVTLTRADLVAGSPSIGAHFHGEFTVRQLLTAAVSESDNTAVDALLKLV-PP -QDVTAFLRAHGITGMRVDMGEAGVGRAYLADPRNRSTPDAAADLLRQLQRGVLLSPSSTH -ALLVLLQAQTQ-PSRLRQGLPHDVQLADKCGTSYTAAYNDIGILTWPDGRSVIVAAFLTA -STASKAEREALFADLARTVANTw ->[subseq from] Beta-lactamase n=1 Tax=Listeria riparia FSL S10-1204 TaxID=1265816 RepID=W7D7U0_9LIST ------------------------------------------------------------- ---EQQLEKRVFFKKEDLVDYSPVTEKHVESGMTIKEIIHAAVAYSDNTAGNLLFNALNGP -KGFQDELRKIKDETTNADRYETELNVAVPGDPRDTSTPEAFSKNLAFLTRQGNLQPKQLD -YFKQTLIENTTGGKLIRAGIPKDYIVGDKTGAGSYGTRNDIAVIYSDDREPLVWVIFSKK -DKEDATYDDQLIADASKVLSQYf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI00099950FE --sQLKKTLESIISGKKATVGISVMSPDEKEMT-GINANQMLPMLSTVKFPLALAVLYEVE -KGKLSMNQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP -ETVQEFMDS---NSFIIKNNEEGMHKDWDSQFINKITPNFAVLLLQEFSNGKILNKTNTQ -WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Serine hydrolase n=1 Tax=Blastomonas fulva TaxID=1550728 RepID=A0A222WXM0_9SPHN ---GLRDELAQLWRSFPGKTGIAVRRIDGDWVV-GHRGGELFPQQSVSKLWVTMAVLEKVD -RGELSLDTEVTITPEDLTLHQPLAARVAREGETVRTLINEALTASDNSANDALLRTAGGP -GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVNALARLARGELLSQNSTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE -TTAGIPARMQLMQAVSRAV---- ->[subseq from] Beta-lactamase n=1 Tax=Cylindrospermum sp. NIES-4074 TaxID=2005457 RepID=A0A1Z4QIU2_9NOST ----LKTAVQNLATANNLTPGVFVVDLDTGAYV-DVNSTASFPAASTIKVPILIAFFQDVD -GGKIRLDEMLTMKQEMMAGGSGNLQYKPAGTYTALEVATKMITISDNTATNILIARLGGM -EVLNERFRTWGLASTVIRNQLPDLPGT------NTTSPRELGNLMAMVNQGNFLSMRSRD -LMLDIMRRTER-DNLLPSGLGTGARIYHKTGDIGT-MLADAGLVDIPTGKRYIASVMVKR -PNND-PRAEKLISSISRAAYQQ- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas panacis TaxID=1560345 RepID=UPI0009F65F9E ---ALARSINAVARSFDGRVGVAVRSIDKGWTV-ESNGDVRLPQQSVSKLWVAMTVLDLRD -SGRLTLDDPITLTRNDLTLHQPVASLLKNGETTVGELLRRALTMSDNTCNDRLLRYVGGP -SAVRDFIARKGLGNIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKKDELLSPNSTA -FLISTMESSKTGKQRMRGAVPVGWSFGHKTGTGQTAGYNDVGLLMAPDGRAYAIAVMIGD -TPRTIPQRQELMQSVVQAVVA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingopyxis indica TaxID=436663 RepID=A0A239GEV3_9SPHN ----LEARIHSLWQSFPGKTGIAVQRIDGDWAF-AERGDDLFPQQSVSKLWVTLTVLDAID -RGELSFDQKVRIGPEDLTLHQPLAARVRSEGMTIRDLIETAITHSDNTANDSLLRTVGGP -KAVNGFIARKDLGAIRFGPGERLLQSSYLADPPDGASPSAIARALTRLARGELLSPESTK -YVLGVMSRTRSGPKRLKAGLPAGWEFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGT -TTSSVPARMALMQAVSGAVADY- ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5U895_9BACT ---DVADRIAAIEGRIGCRIGVAALDTGNRKRL-DYRADERFPMCSTFKFLAAAAVLKRVD -EKQEKLERFVPYDAKEILEYAPVTKEHLKDGMMLGALCEAAIEQSDNTAGNLLLDAIGGP -AGLTNFARDLGDRITRLDRKEPDLNSAIPGDERDTTTPGSMLGEMTRLLTGDVLSQ---- ------------------------------------------------------------- ------------------------ ->[subseq from] Putative beta-lactamase class A n=1 Tax=Sphingobium sp. (strain NBRC 103272 / SYK-6) TaxID=627192 RepID=G2IPD5_SPHSK ---ALVATIRELGRQFPGKVGIAVYNVEAGWTV-EHNGDQLFPQQSVSKLWVAMTLMDAVD -RGKLSLDRAVTIKQSDLTLHQPIAAMVKGEQTTLRNLLDRAMQQSDNTANDSILRTVGGP -EAVRGYLARFGPDSIRFGPGERLLQSAYLSNPPDGASPVGIARALGKLRKGEMLSPHSTR -ELLAIMTDAKTGPQRVKAGVPAGWSYAHKTGTGQSTGYNDVGIMTAPDGTAYAIAVMIGE -TSAPIPKRWELMQSVSRAV---- ->[subseq from] class A beta-lactamase n=1 Tax=Legionella longbeachae TaxID=450 RepID=UPI0012461D96 ---ELSRRISAIEKNSRTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKESLDRVIKMDTKNSVPGSGSLHHIFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSEDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Legionella longbeachae serogroup 1 (strain NSW150) TaxID=661367 RepID=D3HM63_LEGLN ---ELSRRISAIEKNSRTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKESLDRVIKMDTKNSVPGSGSLHHIFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSEDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. SYSUP0001 TaxID=2303576 RepID=UPI0013C35EE9 ----LEQRIDQLGQSFDGTVGIAVRSVGDGWRT-GWRETELCPQQSVSKFWVALAAMEAVD -RGQVSLGDRVTLRRDDLTLHQPIASRILGGGVTLEELLVEALTKSDNTANDKLMRSIGGP -TAVRSFISRHQLGAIRFYDGERALQSRYLADPYDGATAGAIVDALARLKRGELLSPASTA -RLLTIMGNTKTGANRLKGGLKPGWSLSHKTGTGQQAGYNDIGVLTAPDGASYAVAVMIKR -TATPLEVRMTLMNDVVRAVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides clarus TaxID=626929 RepID=A0A1Y3YYH5_9BACE --qTLESKIGDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN -KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD -FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMVYDEy ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000B35F02B ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus arlettae TaxID=29378 RepID=A0A2L0NGC2_9STAP ------------------------------RILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDXRDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Propionibacteriaceae TaxID=31957 RepID=A0A4R6LLY6_9ACTN -----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT -PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVTEVCRAAIQLSDSTAANALMSLTGGP -DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR -RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS -PRPDTERVNEIFAILAREAL--- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides dorei TaxID=357276 RepID=A0A4R4GUB5_9BACE --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=UPI00101CF359 --qTLESKIGDFLKGKKAMVGVAVM-TDRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN -KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHTHQYINKLGICDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD -FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMVYDEy ->[subseq from] class A beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 061049 TaxID=2016501 RepID=UPI000B9767DD -----AALIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT -PDPKVLDRPVFLPPEAICEPAWFAEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP -DSITRFARDNGDPVTQLTEWEPELNT--PDGDRNTTSPRAIGALFAAMIVGRALRTPARR -RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS -PRPDTERVNEIFAILAR------ ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. NIES-3756 TaxID=1751286 RepID=UPI0009E8DEE1 ---SLKNTVQELAAANNLTPGVFLVDLETGGYV-DVNGSSSSPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQQEMVAGGSGNFQKPVGTKFAALEVATKMITISDNTATNMLIARLGGM -EALNERFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNIMTLVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR -PNND-PRAEKFISSVSRAAYQQf ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia bruuniana TaxID=1756149 RepID=A0A5E8CYZ6_9FLAO ----LKKTLESIISGKKATVGISVIGPDTKEVT-GINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMAQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD -TYESFEASEKIISDIGRATYDYy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A139KM17_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLVATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPTDVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDTGNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase 3 n=1 Tax=Bacillus cereus HuA4-10 TaxID=1053206 RepID=J8A8S9_BACCE ------------------------------------------------------------- --------------------------------MFLKELADASVRYSDSTAHNLILKQLGGP -SEFEKILREMGDTVTTSERFEPELNEVHPEETHDTSTPEAIAKTLQSFTLGTALPIEKRE -LLVDWMKKNTTGDKLIRAGVPKGWEVADKTGAGSYGTRNDIAIIWPPNKKPIVLAILSNH -DKEDATYDDKLIAEATKIVLN-- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI0008404574 ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDESEKIISDIGRATYDYy ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. IP1 TaxID=2021637 RepID=A0A2G1LNY5_9SPHN ---HLLAEFDRFAALSDGTVGVAVQDLQTGEIQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGVHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=UPI00104CE4D0 ---SLEDQLKQAIKGKKAEIGIAVI-IDGKDTV-TVNNDIHYPLMSVFKFHQALALADYMG -KQQQSLNFELTIKKEDLKPYSPLRDSFPQGGIDIADLLKYTLQQSDNNACDILFQYQGGV -DTVNQYIHSLGVTDCAIVCTENDMHQDESLCYQNWTTPLAAARLLEIFRKEALFPQEYKD -FIYQTMTECQTGQDRLVALLGKEVTIGHKTGTGDRNACNDIGFVLLPDGHAYSIAAFVKD -SEENNQENSKIIADISRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A430BI38_SPHYA ---HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLIAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium herbicidovorans (strain ATCC 700291 / DSM 11019 / NBRC 16415 / MH) TaxID=1219045 RepID=A0A086PB77_SPHHM ----LLGEFARFATLSDGTVGIAVRDLHNGETL-QYNGDTLFPMASTYKVAVAGKILSLAD -AGTLRLDEKLP---------------RLGTPLSVNTLLDLMLTRSDNEATDTLVARAGGP -QAVHGWLKSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIHHGKALKGPSAA -MLLGIMSRCRTGKARLVGMRPPGTPVAHKTGTLN-GLGNDTGIITLPDGRRIAISVFVMK -DHRGHAARDRIMAEVARAAYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI00101D9668 --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] Serine hydrolase n=1 Tax=Symploca sp. SIO2E9 TaxID=2607812 RepID=A0A6B3MD01_9CYAN ---ELKAQMQAIVAQNKLQPGVFLLDLDTGAYL-DWDSRSIFAAASTIKVPILVAFFQALD -AGKVRLDETLIMESEMIASGSGDMQQQPGKHYTALEVVTKMIAISDNTASNMIIARLGGA -EVLNQQFRSWGLATTAISNLLPDLEGT------NTTSPREIARLMSMVNQGQLLSLRSRD -RLLSIMQRTQN-DSLLPQGLGNGATIAHKTGNIGS-VLADVGIVDMPTGKRYIIAVMVKR -PH-DDPSAQKLIRDISRTAYNYf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter halimionae TaxID=1926630 RepID=UPI00135DE8B1 --kNLAARIEAVADGSRGRIGVAAMDLSTGQTL-GVLDRQFFPMASTSKIAVAATFMEGVE -QGRWSLTSEFPLLWPLRSKSSRAAPVREGKHLPAIELIELMLTRSSNPSTDALLRVVGGP -EAVNDWMRRNGIEDFSLDRDIATLVRATKIDTRDAATPRAMLQLLAGLHNGDFLSAKSRA -VILSAMSRCRTGKRRIPALMPSGAKVAHKTGSLNN-TSSDVGFITAPSGRTYAVAIYVTG -QG-SRSNREARIARIARELLDGy ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI001107C73A ----LKNAVQNLTSNLNLKPGVFLVDLDTGNYV-DIDASTSFPAASTIKLPILIAFFQDVD -AGKIRLDEMLTMQQDAIAGGSGNLQKSAGTQYAALEVVTKMITISDNTATNMLIARLGGI -DALNQRFRSWGLTTTVIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSVPSRD -LMLDILRRTQK-DTLLPSGLGTGARVYHKTGDIGT-MLADAGLIVVPTGKRYVAAVMVQR -PNND-PRAEKLISSISRVAYQEf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC607D -----QQALEEVLTDSPGVFGVAAAHLETGKSA-GNLDDQLFQLASAFKIPIMVTLMREVE -AGKLRLDQRVTLKRDERVPGSGVLQELDAGALTVKDLATLMTIVSDNYATDLVLELIGGI -EQVTAHMHELGLKDIHLRHTCWQLLNSQPTLENNVATPADLNRLLIMIAQKEILTPASCD -LMLDILRRQQY-NSRLPFLLPEGTKVAHKTGTVN-AVVNDAGIIYLPNGKGIAITVLSRG -IT-EKSAAELTIARVARAIYDQ- ->[subseq from] Penicillin-binding protein n=2 Tax=Calothrix sp. 336/3 TaxID=1337936 RepID=A0A0T7BRF9_9CYAN ----LKTAVQNLAASNNLTPGVFLADLDSGSYV-DLNGGAAFPAASTIKIPILVAFFQDVD -QGKIRLDETLTMEKEMVATGSGDMQKAVGSKFSALDVATKMMVISDNTATNMLIARMGGV -ETLNQRFRSWGLNTTNIRNILPDLEGT------NTTSPKELGNLLGMVSKGNLLSMTSRD -RLLYIMRRTVR-DNLLPAGLGQGAIIAHKTGDIGN-MLGDAGLVDLPTGKRYIAAVMVQR -PRND-TSAEKMINSVSRVAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLF TaxID=1985879 RepID=A0A430DQE5_9SPHN ---DLTRAITTLLANFNGTAAAAVTSIDSGWTV-AYNGSRPMPQQSVSKLWVAMTALDLLD -QGKLTLDDPVVVRREDLTLHQPIASLVKGDGTTVRELMRRALTMSDNTANDRLLTYVGGP -NAVRAFLARRGIQNIRFGPGERLLQSAYVANPPDGAGATAIAEALMRLKQGKLLSPNSTR -YLLDTMAASRTGRARLHAALPPGWTLAHKTGTGQNAGFNDVGILTAPDGRSYAVAVLIGD -TRAPMRDRQQLIQQVVHALV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MJK6_9BACI ----WQQAVEDVLKEAPGIFGIAAMHLETGETV-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELEAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIAITALSR -GVTDTEAAEVTIARVAKAIYE-- ->[subseq from] class A beta-lactamase n=1 Tax=Erythrobacter aquimaris TaxID=255984 RepID=UPI00135E9EE1 ---MLEARLQQIGEGFAGEVGIAAVEVTSGATM-AYNGARPFPQQSVSKLWVSLTALDLVD -EGALDLSEPVAIRREDLTVYQPIRDIVRTRGTDYRDLMERALTQSDNTANDRILRRVGGT -QAVEAFMRRKGIEGVQFGTDERSKQSDYLDDPIDGASASGMAQALARLARGELLSPRSTE -LILSTLENTKSGPKRLKGGVPSGWSIAHKTGTGQHSGYNDVGVLTAPDGTKYALAVMIAR -TRTSYAARFEMMQSVTRAVVEY- ->[subseq from] PenP, beta-lactamase class A n=2 Tax=Nostoc sphaeroides TaxID=446679 RepID=A0A5P8VZW9_9NOSO ---SLKNAVQNLAAANSLTPGVFIVDLDTGNYV-DVNGSINFPAASTIKIPILIAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGDMQKSAGTQYAALEVATKMVTISDNTATNMLISRLGGM -EALNERFRNWGLTNTIIRNQLPDLQGT------NTTTPKELGNLMAIVSQGSLVSMPSRD -LMLDILRRTQR-NTLLPSGLGTGARVYHKTGDIGT-MLADAGLIGVPTGKRYVATVMVQR -PNND-PRAEKLISSISRAAYEEf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. HT-58-2 TaxID=2023229 RepID=A0A2L0GGQ4_9SPHN ---SFEQRIAELANPAMGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKVAVAATYLELVE -KGRYSLTSEFPLLLPVRSAFSSARAPVREGQMQAIDLIEIMITRSSNPATDALLAAVGGP -AAVNDWMRRQGINQFSINRDIATLVRATHIDSRDAATPRAMAQLLAGLYRGEYLSDQSRQ -VLLGAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDVGLIECPDGRVIAVAIYVTG -QG-TKLAREERIAAIARALYDGf ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A078QQC5_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Uncharacterized protein n=1 Tax=Trichormus variabilis NIES-23 TaxID=1973479 RepID=A0A1Z4KMI8_ANAVA ------NVVQQLATATNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD -AGKIRLDELLTMKQEMVAGGSGNFQYKPAGTYPALEVATKMITISDNTATNMLITRLGGM -EALNERFRSWGLTNTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYVVAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Alr4543 protein n=1 Tax=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) TaxID=103690 RepID=Q8YNM1_NOSS1 ------NVVQQLATATNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD -AGKIRLDELLTMKQEMVAGGSGNFQYKPAGTYPALEVATKMITISDNTATNMLITRLGGM -EALNERFRSWGLTNTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYVVAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. GW247-27LB TaxID=2012632 RepID=A0A270BE67_9SPHN ----LEERIFGLWRAFPGKTGIAVQRIDGEWTL-QQRGDDLFPQQSVSKLWVTLTVLDAVD -RGALTLDRKVSITPADLTLHQPLAARVRSEGMSVRDLIETAITHSDNTANDSLLRTVGGP -DAVRRFIAAKDLGSIRFGPGERLLQSNYLANPVDGASPSAIARALTRLARGTLLSPESTD -YVLGVMSRTHSGPKRLKAGLPAGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS -TTASIPQRMALMQAVSGAVAE-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Cyanobacteria (miscellaneous) TaxID=1983111 RepID=A0A2T1FKV4_9CYAN -------QIESAIDQYSLSAGMFFLDLDTGDYL-DIKGDRVFPAASTIKLPILIAFYQDVD -AGKISLDETLVMKSDLVASGSGTMQDEPDNTFSIRETVDKMITISDNTATNMIIERLGGI -AKLNERFRSWGLTDTRIRNWLGDFQGT------NTTSSVDMVKLLAMLSRDKLVSESSRE -QALELLRRTTT-RTLLPSGLGAGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR -PYND-PIVRDFVRRISRIVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium hankyongense TaxID=1813876 RepID=A0A328AXD3_9CAUL ---ELQARLDALAAAYHEPVGIAVVDVKDGWTA-AVDGDSAYPQQSVSKLWVAMSVLDAVD -HGGLALDQAVVVTRDDRSVYQPLGERVGEKGTTLHDLLRRALTESDNAANDKLMREVGGA -GAVTDALAEKGLSHIAVGAYERELQAAYLADPPDGASPSAVAHALAALERGDLLSKASSE -TMLTLMGEARTGRMRLRGGLPPGWKIAHKTGTGPSVGINDVGLLTAPDGRVYAVAVMMRQ -TRKPVPQRLALMQAVTRAVADSw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YKP9_9BACL -----QQALEDVLTDSPGVFGVAATHLETGKTA-GNLDDQLFQLASAFKIPIMVTLMREVE -AGNIRLDQRVTLKQDERVPGSGVLQELDAGALTVKDLATLMTIVSDNYATDLVLELVGGI -EQVTAHMHELGLKNVHLRHTCWQLLNSKPTLENNVATPADLNRLLIMIAQKEILTPASCD -LMLDILRRQQY-NSRLPFLLPEGTKVAHKTGTVN-AVVNDAGIIYLPNGGTIAITVLSRG -VT-EKSAAELTIARVARAIYDQ- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=R6FI74_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAKISKAVYDY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SF68_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAKISKAVYDY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4IGB9_9NOSO ---SLKNTVQELASANNLTPGVFLVDLETGGYV-DVNGSSSSPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQQEMVAGGSGNFQKPVGTKFAALEVATKMITISDNTATNMLIARLGGM -EALNERFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNIMTLVSQGNLVSMRSRD -QILDIMRQTER-DHLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR -PNND-PRAEKFISSVSRAAYQQf ->[subseq from] serine hydrolase n=1 Tax=Nostocaceae TaxID=1162 RepID=UPI0009FDE5D9 ------NVVQQLATATNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD -AGKIRLDELLTMKQEMVAGGSGNFQYKPAGTYPALEVATKMITISDNTATNMLITRLGGM -EALNERFRSWGLTNTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYVVAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Fischerella sp. PCC 9605 TaxID=1173024 RepID=UPI00047C0C34 ----------------NLTPGVFVVDLDNGGYV-DINASSSFPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQKEMVAGGSGDMQYKPAGSFKALEVATKMMTISDNTATNMLITRMGGI -EALNQRFRSWGLTTTVIRNQLPDLQGT------NTTSPKELGNLMGMVSQGNLVSMISRD -RILDIMRNTVR-NTLLPSGLGQGATIAHKTGDIGT-MLADAGLVDLPTNKRYVVAVMVKR -PNND-PNARKLISSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI00136B07B4 ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEVLKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRTAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Legionella sainthelensi TaxID=28087 RepID=A0A0W0YJM8_9GAMM ---ELSQRIDAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -KYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPPHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] Serine hydrolase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A2D1R0W0_SPHYA ---HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPDSTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. EG6 TaxID=1874061 RepID=A0A2Z5UER5_9SPHN ----LAERINFLWRGFPGKTGIAVQRIDGEWAI-AERGGELFPQQSVSKLWVALTALDAVD -QGRVRLDQQVRIGPEDLTLYQPLAARVRAQGMTLRQLIETAITQSDNTANDSVLRTVGGP -GAVRAYMAKKDLGAIRFGPGERSLQSNYLANPIDGASPTAIASALTRLARGTLLSPESTE -YLLDVMSRTKSGPKRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TTSPIPARMALMQAVSSAVAE-- ->[subseq from] Serine hydrolase n=1 Tax=Paraburkholderia sp. 7MK8-2 TaxID=2419777 RepID=A0A494XNP1_9BURK -------------SATTGSFGIAVIDLGSGAVT-GVNLDRPYPMMSVFKAPLGVTVLDQVE -KGSIGLDQVVTLTRADLRNTSPIREHFVGDKFTVRQLLDYGISQSDNSAADALVRLVGGP -LVVTRFLQAHGVEGMRVEMDEGTVSHAYLADPRNRSTPRAAAAFLRKLWAGELLPPRETQ -ALLNLLYAQTT-PSRLRKGMPAGVRLADKCGTSETAAYNDIGIVTGPNGHTAIVAAFLTA -SQATQAEREAWFAELGRQV---- ->[subseq from] serine hydrolase n=1 Tax=Sphingopyxis sp. 2PD TaxID=2502196 RepID=UPI0010F7D21B ----LAERINFLWRGFPGKTGIAVQRIDGEWAI-AERGGELFPQQSVSKLWVALTALDAVD -QGRVRLDQQVRIGPEDLTLYQPLAARVRAQGMTLRQLIETAITQSDNTANDSVLRTVGGP -GAVRAYMAKKDLGAIRFGPGERSLQSNYLANPIDGASPTAIASALTRLARGTLLSPESTE -YLLDVMSRTKSGPKRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TTSPIPARMALMQAVSSAVAE-- ->[subseq from] Serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium USR001 TaxID=1880991 RepID=A0A1C0VEZ7_9CYAN ----LKAEIDKLTAQYSLTPGVFIVDLDTGGYT-SVSSDASFAAASTIKVPILVAFFQAVD -EGKVHLDQMLTLRSEHIASGSGDLQDAPGKKLTALEVATKMIEISDNTATNMLIDLLGGS -EALNQTFQTWGLKVTAIRNSLPDLAGT------NTTSPRELVNLMAQVNQGSLISQKSRD -RLFHIMRQTQN-DSLLPRGLGEGAMIAHKTGNINS-LSADVGMVDMPNGKRYLVAVMVKY -GK-NQKTAEKLIRDISRTTYQY- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A412QCC1_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYQY- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=UPI000BBC325F ---SLKNTVQELASANNLTPGVFLVDLETGGYV-DVNGSSSSPAASTIKIPILVAFFQDVD -AGKIRLDEMLTMQQEMVAGGSGNFQKPVGTKFAALEVATKMITISDNTATNMLIARLGGM -EALNERFRSWGLTTTAIRNPLPDLQGT------NTTSPKELGNIMTLVSQGNLVSMRSRD -QILDIMRQTER-DHLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR -PNND-PRAEKFISSVSRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6MDB2_9BACL ----WQQAIDEVLQEAKGEFGVAVTHLESGMTV-GHQADQLFQMASVFKIPIIVTLMRDVE -AGKIRLDQRIPLRYEERVPGSGVLQELDSGALTVKDLAMLMTIVSDNYATDMVINLV-GL -GNIEKHMRELGLESIYLPQTCWQLLNGAPTTENNVATPADLNRLLSMVAKKEILSAASCD -LILDILRRQQY-NSRLPLLLPPGTRVAHKTGTVN-GVVNDAGIIYLPEGGQIAISVLSRK -VEE-KQEAERTIAKVARAVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. 39858 TaxID=1710890 RepID=A0A1W5CPW4_9NOST --------VQQLATANNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD -AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI -EALNERFRSWGLTTTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Trichormus variabilis (strain ATCC 29413 / PCC 7937) TaxID=240292 RepID=Q3MDA5_TRIV2 --------VQQLATANNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD -AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI -EALNERFRSWGLTTTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacillus salarius TaxID=284579 RepID=A0A3R9NY76_9BACI ------------------------------------------------------------- ------------------------------TGMTLLELSEAAVRSSDNTAGNFLFKKLGGP -DEFEQALRQIDDNVTQADRYEPDLNEFTPGDTRDTSTPIALANNLQAFAVGDLLSDEKRE -LFTDWLQGNATGDTLIRAGAPEGWNVGDKSGAGSYGTRNDIAVVWPPNREPIVIAIMSRH -DTEDAKYDDKLIAQVAEET---- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. B3058 49 TaxID=2183925 RepID=A0A2V5D1Z0_9SPHN ---AIQQRVASIVAGARGRVGVAAMDLDGGGQV-LINPDMPFPMASTAKVAVAATFLQMVE -QGKYRLDQQLPMMMPVPEPRNLVAMVRPGPVFTAQTLLEKSITRSDNHATDGLIAAVGGI -GAVNRFLMQTGISGQHLDHTMATLVRARAVDTGTSSTPRAMIALLSAIDRGGALSPQARA -VLLDTMTRTSTGRNRIRAGLPEGVLLAHKTGTLA-GVTDDVGIIRMPDGRHLALAIFVAG -PE-NHTAQAGMIARIASVVYEGf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. Leaf23 TaxID=1735689 RepID=UPI0006FF376F ---ALVAAINALGDGFQGRVGIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGRYALDTPVTITRSDLTLHQPVAYLMKDGATTVGDLLRRALTMSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLSPTSTR -WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TSRPVQERQQLIQTVVSSIV--- ->[subseq from] Serine hydrolase n=1 Tax=Phyllobacterium myrsinacearum TaxID=28101 RepID=A0A2S9JYA4_9RHIZ ---ALKHRLEALVQGKDGRVGICAQD-QKGTAV-CVRGEERFSLQSVVKLIAGAAVFDAAD -RGLTDLKEPIVVKPENLSLVQPLAKIVEREGTNADDLVRRAIVDSDSAAVDILIERLGGP -AKVDQFAEGKGILGIRVDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLLSTGSTQ -KLLAIMAETVTFPDRLRAGTGEGWAVAHKTGTSRNVATNDVGILTAPDGGKIAVAVFVAD -SRETPTQRSAIIAGAAQAVTEAy ->[subseq from] Beta-lactamase n=1 Tax=Oscillatoria nigro-viridis PCC 7112 TaxID=179408 RepID=K9VHM2_9CYAN -----KPQIESAIEQYSLSAGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFYQDVD -AGKVSLDETLVMKSDLVASGSGTMQDSPNGTFSIRETVDKMITISDNTATNMIIERLGGI -AKLNERFRSWGLTDTRIRNWLGDFQGT------NTTSSVDMVKLLAMLSRDKLVSESSRE -QALELLRHTTT-RTLLPSGLGPGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR -PYND-PIVREFVRRISRIVYNY- ->[subseq from] Beta-lactamase n=3 Tax=Bacteroides TaxID=816 RepID=R6S9U2_9BACE ----LKEQIQAIIHSCKAQVGVAFIW-NGQDTL-SINNDRPYPLMSVFKFHQALAVTHWLE -TRHLSLDTVLYITPEDLKPYSPLRDRYPQGNLSVRELLKYTLQQSDNNACDILFRLTGGP -QETDRYIRSLGCSHFSITATEDDMHVDLNRSYDNWTTPLEAARLLEIFLTRELFRPSDRQ -FIRQTLTECETGKDRLVKPIPSGAVIGHKTGTGDCNGINDIGFFLLPDGSRYSLAVFVKN -SEEDAPATAGVIAAISEAVWN-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides clarus TaxID=626929 RepID=F3PFE7_9BACE --qTLESKIGDFLKGKKAMVGVAVL-TDRNKIL-LHNNKMNYPLLSVFKFHVALTVLDKMN -KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHIHQYINKLGVCDFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADKKELFDPIYKD -FLWNTMIATSTGSNKLKGLLPSNAIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMVYDEy ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7WA14_9BACL ----WQQAVENVLKEAPGIFGIAAVHLETGETA-GHLDEELFQLASTFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLPHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMQDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVNT-VVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Anabaena sp. YBS01 TaxID=2490939 RepID=A0A5Q0GMB7_9NOST --------VQQLATANNLSPGVFLVDLDTGGYV-DINAANALPAASTIKIPILVAFFQDVD -AGKIRLDEVLTMQQEMVAGGSGNFQYKPAGTYPALEVATKMITVSDNTATNMLIARLGGI -EALNERFRSWGLTTTVIRNILPDLPGT------NTTSPKELGNIMTMVSQGNLVSMRSRD -QILDIMRQTER-DNLLPSGLGAGARVYHKTGDIGT-MLADAGLIDTPTGKRYIVAVMVQR -PNND-PRAEKLISSISRAAYQQf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000841404D --nELKKRIENIITGKKVDVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE -KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT -DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK -WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVHD -TYENFNDSEAIIADIAKTVYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. HDW15C TaxID=2714944 RepID=UPI0014073625 ---QLERRIDELGKGFAGRVGIAVESIDDGWTT-SWNGNELSPQQSVSKLWVSITALDAVD -KGKVRLTDAVSFDRSDLTLHQPIAARVLGGGTTLADLMFKAITTSDNTANDKLMRSVGGP -DAVRAMIRNKGLGAIRFYNGERSLQSRYIEDPYDGASANAIVHALSRLKRGELLSPSSTA -RLLNIMGNTKTGANRLKGGLRPGWSLSHKTGTGQQAGYNDIGILTAPDGSSYAVAVMIKK -TSVPLPTRMTLMNNVVRAVIAQ- ->[subseq from] Uncharacterized protein n=1 Tax=Tannerella sp. CAG:51 TaxID=1262979 RepID=R7DH77_9BACT --rELKMRIASVLKEKRAIVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH -KNNLSLDTDIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT -KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLFRDEYGN -YLRKIMIETSTGNDKIKAGLPERVVMGHKTGSSDRNGDNDLAFVQLPDGQRYCIAVFIRD -SKEDDKTNAAIIASVSKVVYDY- ->[subseq from] class A beta-lactamase n=1 Tax=Legionella sp. km542 TaxID=2498108 RepID=UPI0013152018 ------------------------------------------------------------- -------SQRISYSKKDLTSWNPITEKHLSSGMTVEQLCAASISYSDNTAMNLLVKQMGGL -DQMTLFAHSLGNTSFRQDNWPEEAYSGGKGDLKDSSTPKDMANSLQKLSFTDVLAKPQRE -MLISWLKANTTGDLRIRAGLPKGWIVADKTGTGGYGTTNDLGIIWPPGCAPIVVAIYYSS -NDKQAKKRDDIVAIATRLLIT-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. K2R01-6 TaxID=2320861 RepID=A0A418W7J8_9SPHN ---ALQSAIRSLGASFDGSVGIAVRDVHTGWVV-DYNGRQPMPQQSVSKLWVAATLLEGVD -QGRISLSEMVMIRPSDLTLHQPIRQLVGKNGESVSGLLARAMTQSDNTANDSLLRRAGGP -AAVRSFLTSHGITDIRFGPGERLLQSRYLADPPDGATAIGMVDALAKLKRGELLSPRSTD -YLITTMRASRTGPKRLRGGISDGWLFGHKTGTGQSTGYNDVGLLTAPDGRTYAVAVMIGS -TRRSIPERMSLMQAVTRAVIS-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Flavobacterium TaxID=196869 RepID=UPI00131E6380 --dELRKEINQIISSKKADVGISILNLENGDTL-SFNGNKQYPMLSAFKFHVALTVLNKID -KGELSLNQKLFIKKHELLGWSPFKERYPNGDISLKEALEWTVSLSDNNLCDILIRLVGGV -KTVDNFICN---SDFIIKNDEEGMHKNWDAQFLNTITPNFSNQLLNRFLEKKLLTKKSTK -FLYETMVATSVGQNRIKGKLPSKTEVAHRTGSSFTGAINDIGIVKLPNGNRLIISVFVHN -TTEIFKDGEEIIANISKVTWNYy ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI000999A604 --nELKKRIENIITGKKADVGVSIIGGNKNDKV-QINGNQLYPMLSTFKFPIALTVLHKVE -KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT -DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK -WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTGAINSYGIIELPKNKKIVITVFVYD -TYENFNDSEAIIADIAKTVYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI000DEF7333 ----LAARIAELGRGFDGRVGIAVESVERGWRT-GWKTDELYPQQSVSKFMVALTVMDRID -HGALRLDQPVTLTRSDLTVHQPIRDVILANGTTLQDLLNRALTQSDNTANDKLMRLAGGP -EAVRGFIAERRLGEIRFADGERALQSRYIDDPYDGAAPFALVDTLARLKRGELLQPASTA -RLLTIMSDTVTGKNRLRGGLKAGWTLAHKTGTGQQAGYNDIGVLTAPDGRSYAVAVMMKR -TAVPLAVRMTLMNEVVRAIIA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A085K7R1_SPHYA ---HLLAEFDRFAALSDGTVGVAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLALDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYEFMLDPRDTATPLAMNQLLVAYESGKALKPDSTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinithalassobacter portus TaxID=2676234 RepID=UPI000D6E9D8B -----LSTITALESQFDGIVGIAVTSVDEGWSV-AANGERRMPQQSVSKLWVAMTVLDYRD -QGRLSLDDPYTVTKADLTVHQPVATLIGENGTTIRELLRRALTNSDNTCNDILLRYVGGP -DSVRDFISRKGLGAIRFGPGERLLQANYIADPPDGATATAIAQALARLKRGDLLSADSTS -WLLATMESSHTGRQRLRGAVPAGWSFGHKTGTGQTAGYNDVGILTAPDGKSYTIAVLIGD -TSRTIPQRQELMQAVVASVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Moorea bouillonii PNG TaxID=568701 RepID=A0A1U7N5F2_9CYAN ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFHLEQGKWISPQSRT -DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQAYDY- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacteraceae bacterium CCH12-C2 TaxID=1768805 RepID=UPI0008300A61 --nSFEQRIADLANPALGRIGVAAVDLTTGEQV-MVLGDQLFPMASTSKIAVAAAYLELVE -QGRYTLTSEFPLMMPVASASSPKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP -SVVSDWVRRQGINDFSINRDIATLVRARHIDTRDAATPRAMVRLLEGLYRGDFLSDQSRQ -VILSAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGIIETPDGRAIAVAIYVTG -QGG-KAAREERIAAIARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Moorea sp. SIO4A1 TaxID=2607835 RepID=A0A6B3MSI8_9CYAN ----LQKQIQTLVKQHQLQPGIFIHDLDTGAFL-ESNSRLIFPAASTIKLPILIAFFQDVD -AGKVFLDEYITMKPEMIAGGSGNMQQKPGKQYKALEVATKMITISDNTATNMLIERLGGI -EVLNQRFRSWGLKKTVLRNPLPDLPGT------NTTSPRELASLIFHLEQGKWISPQSRT -DLIDIMIQTKT-NTLLPQGLGNGATIAHKTGTLGR-LLADVGLVKMPNGKRYIISVMVKR -PFND-ASAEKLIRTISRQAYDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis lindanitolerans TaxID=2054227 RepID=A0A2S8B6P6_9SPHN -----GDRIASLWRAFPGKTGIAVQRIDGEWAI-TQRGADLFPQQSVSKLWVAMSVLDAVD -DGRISLDQKVRIGPEDLVVHQPLAARVRSEGMSVRDLIETAITHSDNLANDSLLRTVGGP -NAVRAFITKKDLGSIRFGPGERLLQSKYLADPIDGASPAAIASALTRLARGTLLSPASTD -YLLGVMTRTHSGPKRLKAGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TTSSIPARMALMQAVSGAVAE-- ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI00099AEADA ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYTVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA -FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHFAIAVFVKD -SMESEEVNYGMIAQISKVVWDA- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F5CEB7_KLEPN ------------------------------------------------------------- ---------------------NPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRA---------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas mali TaxID=40682 RepID=UPI00082FA8CC -----TNLVPSLTRDFGGKVGIAVMSIDDGWTV-TSNGDLKLPQQSVSKLWVAMTVLDLRD -QGKLTLNDPYTVRKDDLTLHQPIAALVKDDGTTVGELLQRALTQSDNTANDCLLRLAGGP -TAVRAFLAKKGIADIRFGPGERLLQSRYVADPPDGAAPRAIVTALARLKKGELLSPASTQ -YLMSTMESSHTGRQRLRGAVPEGWTFGHKTGTGQTAGYNDVGFLISPNGKAYAIAVMIGD -TPKTIPQRQQLMQAVV------- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia bruuniana TaxID=1756149 RepID=UPI000999D75B ----LKKTLESIISGKRATVGISVIGPDTKEVT-GINGDQMLPMLSTVKFPLALAVLHEVE -KGKLSMAQKLFIKKEELLEWSPFKEKYSQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD -TYESFEASEKIISDIGRATYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000995255C ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVNN -TYESFDDSEKIISDIGRATWNYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. ZJ279 TaxID=2709796 RepID=UPI0013EB7FB0 ----LRHNIQKIIENKQATIGVGLI-VDGKDTL-TINNNHNYPTLSVYKFHLALAVLNYMQ -INNISLEHEIFIAKDDLLPHSPLRDTNPDGNMSIADLIKYSVAKSDNNACDILFKYIGGT -TKVDQYIKSIGIENCHIAATEAKMHEQFENQYLNWSSPLSAVRLLEVFRNNKFLSPIYQD -FLWKTMVETTTGSNKIKSLLPAKTLVANKTGSSFRNAENDIAIIRLPNGKYYSLAVFITD -SMENDDVNAKIIADISKTVYDY- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 7336 TaxID=195250 RepID=UPI000375DD0C ---ELQARIEGLALNPQLRLGMVVVDVEGRNYA-NVRGSERFAAASTIKLPILVALLEAVD -RGEVRLGELLTLEPSAIVGEAGSLQTQPPGSHSVLDTATWMIEVSDNTATNLIVNRLGGR -DVLNRRFRQWGLQQTQLSNPLPDLEGT------NTTSPDDLIRLLEEIERGHLLSMRSRD -RLLSIMQRTQN-ADLLPRGLGPGAIIAHKTGTLRS-LLGDVGLVDLPNGRRYAIAVLVAR -SH-SDPEASELIRQVSREVYNYw ->[subseq from] Beta-lactamase n=1 Tax=Legionella sainthelensi TaxID=28087 RepID=A0A2H5FHC0_9GAMM ---ELSQRINAIEKNSRTVMGITAIHIEKNKVI-SHNSNQRFFMASTVKLPIALAFLHRVD -ENKDSLDRVIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVTNGP -RYVASRMSALGFKNIFVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] CME family class A extended-spectrum beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI00099A1DBD -htSILNDINAVTKDRKATVAVSVLGIENEFQFsNANGNLKMPMLSVFKFHIALSVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -KTVQKLMDVNGVKNFQIKYNEEEMHKNVKALYANYTTTASMVKTLKAFYKGLFLSKRSTI -FLMDIMTKTNTGMTKLPGLLP-KVKMARKTGSSGTVAENDSGIVTLANGKHYAIAVFVKD -SMESEEVNCGMIAQISKIVWDT- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia TaxID=308865 RepID=UPI00099A1D50 ----LKKTLESIISGKRATVGISVIGPDTKEVT-GINGDQMLPMLSTVKFPLALAVLHEVE -KGKLSMAQKLFIKKEELLEWSPFKEKYSQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD -TYESFEASEKIISDIGRATYDYy ->[subseq from] Beta-lactamase n=1 Tax=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) TaxID=63737 RepID=B2J7F0_NOSP7 ----LKNAVQNLAANYNLAPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM -EALNQRFRTWGLTTTTIRNSLPDLQGT------NTTSPKELANLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacillus pumilus TaxID=1408 RepID=A0A2L0NG81_BACPU ---------------------------------eSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDXRDTTMPVAMATTLRKLLTGELLT----- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides TaxID=816 RepID=UPI0007C4E695 ----LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A497KLV1_9ARCH ---SLQAAIEEQAEGFKGTLGVSVKHLYTGETA-SINGDKVFPTASVFKIPVIVEFFRQVD -AGTLSLDQQLLLSERDKVPGSGVLKELTEGLVTYKDLLSLMMIVSDNTATDLITEIV-GF -ENINATMKELGLKETQVTRYCRQILFSLETEDNDVTTPNEMNRLLELIVDGKAASRENCN -KILEIMEKCQTGGYRIPKYLPKEVRLQRKTGSLP-GIRNDVGIVTIKETEKYTITCFTMD -AE-DVYAAEEVLAKVSKAVYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia meningoseptica TaxID=238 RepID=UPI00099A6C6B --nELKKRIENIITGKKADVGVSIIGGNKNDKL-QINGNQLYPMLSTFKFPIALTVLHKVE -KGELKMSQKIFIKKEELLDWSPFLEKYPQGNITLEDALMWMMCYSDNNLTDILIRLIGGT -DTVQKF---IGTKDFIIKNDEEDMHKDWDSQFINKITPNRATQLLDKFYQGKILNGVNTK -WLYEAMLNNKTGLKRLKGKLAADIKVAHRSGTSFTAAINSYGIIELPKNKKIVITVFVHD -TYENFNDSEAIIADIAKTVYDYy ->[subseq from] serine hydrolase n=1 Tax=Nostoc punctiforme TaxID=272131 RepID=UPI000A047337 ----LKNAVQNLAANYNLAPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM -EALNQRFRTWGLTTTTIRNSLPDLQGT------NTTSPKELANLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYQEf ->[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. YT30 TaxID=1735012 RepID=A0A120GAE0_9SPHN ---RLQSRMRIIEANAGGTLGAELFDAASGLSI-GLNQDRRFGHCSSFKLSLAAKILSANA -AGEIDGNKLIRWSEDDLMFVSPFTTQRLDEGATMLELAEFTQKYSDNAAANILLRELGGP -AALTGFWRSIGDDVSRLDRTEPALNNVPVTEVRDTTTPAAMARTVAKLIYGDALPDAERA -ILKQWMIDTPTGVRRVRAGLEEGWVAGDKTGTSFGSLYVDIGFAEAPQKPPITFATYYRA -RETHDPASEATLAQVGKIISD-- ->[subseq from] Beta-lactamase family protein n=1 Tax=Blastomonas sp. RAC04 TaxID=1842535 RepID=A0A1B3N3Z2_9SPHN ---GLRDELAQLWRSFPGKTGIAVRRIDGDWVV-GHRGGELFPQQSVSKLWVTMAVLEKVD -RGELSLDTEVTITPEDLTLHQPLAARVAREGESVRTLINEALTASDNSANDALLRTAGGP -GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQNSTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE -TTAGIPARMQLMQAVSRAV---- ->[subseq from] Uncharacterized protein n=2 Tax=Chroococcidiopsis TaxID=54298 RepID=A0A433V6I5_9CYAN -----------------------------------------------------MAVLNQVD -RGNLKLDQKIRIEASDIVQGSQVLDENSQGKFSLSELLQYMVSKSDNTACDVLLRLIGEP -QRVTEYLSSLGINDIVVANTEKELAQDSTVQYRNSATPDAAVVLLRTLYEGRGLSKTSQA -LLLQWMTEAQTGLKRIKGLLPEGTVVAHKTGTSSTAATNHVGLVTLPSGQHLAIAVFVSN -SQATDVIREEVIAKVARAAWDEw ->[subseq from] class A beta-lactamase n=1 Tax=Propionibacteriaceae bacterium NML 020265 TaxID=2016499 RepID=UPI000B97A94E -------LIADLERRHDVRIGLSAAALTRGRRL-DHRADERFLMLSVFKAIAAAAVLDGIT -PDPKVLDRPVFLPPEAICEGPTWFEQIAARRPSVAEVCRAAIQLSDSTAANALMSLTGGP -ASITRFARDNGDTITQLTEWEPELNT--PNGDRNTTSPRAIGALFAAMIVGRALRTSARR -RLTDWMLGNQTSDQRFRAGLPAGWTLADKTGSGIDATANDVGIAFDPAGNAYQLAVLTSS -PRPDTERVNEIFAILAR------ ->[subseq from] serine hydrolase n=1 Tax=Sphingobium vermicomposti TaxID=529005 RepID=UPI001422B2BC ---RLLAEFARFATLTDGTVGIAVRDLHSGQSI-GINNDTLFPMASTYKVAVAGKIFALAD -AGALSLDERLP---------------RLGTPLSVTTLLELMLTRSDNEATDVLVARAGGP -QAVNSWLQSIGIRGQRVDSNTAQLLAAFAADPRDTSTPRAMNDLLSAIHHGRALKASSSA -ALIAIMARCKTGKARLAGMLPPGTMIAHKTGTLN-GLGNDTGIISLPDGRIFAISVFVMK -DRRGHVLRDRIMAEVARAAYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Altererythrobacter halimionae TaxID=1926630 RepID=UPI00135DDE0D ---TLDRQLSEIGSRFAGQVGIAVRPVEGDRTM-QYRGLELFPQQSVSKLWVSLTALRQVD -AGKLSLDEARVVTLEDLTLHQPIRDEVLASGTEYRDLMQRALTRSDNTANDIILRRVGGP -DAVQATLNRLGLSSIRFGTDERTKQSGYLADPIDGAAPVAIAAALTRLAKGELLSKDSTA -LLLDTLAETRSGPNRLKGGLPPDWRIAHKTGTGQQTGYNDIGILTAPDGRRYAVVVMIAR -TEERVPDRMAMMHEVVGAVAEY- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9QFS1_9BACT ----LVEDLEKASRAYSGRVGIYIKDLETGKSW-EYNADRRFPSASLIKVPIMAAVFESIR -GGRLSLDTQIKLTRGLRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDAV-GM -DYLSGAFRAMNLEQTNITPEGMSLSSR-PVRRENYTTAREMGGLMERIYAGKLVDREASE -FMLDVLKHTKS-RSRLRRGLPLGWEIGHKTGLLRK-ACHDVGVVFSPRGD-FVIAVLTSE -VP-SYSSAKTFISRVAKLTYKYy ->[subseq from] Beta-lactamase n=3 Tax=Bacteroides TaxID=816 RepID=A0A4V6P7U6_9BACE ----LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. CRKS33 TaxID=1710888 RepID=A0A1B7WCZ0_9NOST ----LKNTLQSLAANSDLTPGVFLLDLDNGAYV-DINGNTSFPAASTIKIPILMAFFQDVD -AGKIRLDEMLTLEKEMIVGGSGNLQYQAPGGYTALDLATKMITISDNTATNMLVAKLGGQ -ETLNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSSAYQYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=UPI001363C902 --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A395UNM2_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A412E085_BACSE --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A397WFK9_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase n=8 Tax=root TaxID=1 RepID=A0A0P0M3W0_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium sp. Fuku2-ISO-50 TaxID=1739114 RepID=A0A102D8X3_9SPHN ---AIQQAVEAITARAHGRIGVAAADLDGGGQV-LINGDMPFPMASTAKIAVAGTFLTGVE -QGRFRLDQSLPMMMPVAERRGSSAPLRAGPVMSAQQLMELMITRSNNNATDGLITAVGGV -STVNAWLARNGIVGQHLDSTMATLVRAKTIDTRTASTPRAMLALLSAIDRGTALSPQSRA -VLLDTMTRTSTGKNRMRAGLPDGTVFAHKTGTLA-GVTDDVGIIRLPDGRHLALAIFIAG -PE-SHTSHAMMIADITRALYDGy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A224A905_SHISO ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTQ---------------------- ------------------------ ->[subseq from] Beta-lactamase class A protein n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' N6 TaxID=1261031 RepID=A0A2L2N835_9NOSO ---SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDAIAGGSGTLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI -EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD -LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYEEf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GKJ9_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLATLGGP -VAIQQWLSSHQIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNKLDNGTVLTAQSRA -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAIFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000CD2D16C -----------------------------------------------FKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HWU0_9BACT -----PSQFEKIAPAAKGPVGVAAQLLESGETA-SLHGDEHFPMHSVYKLPISMAVLQRVD -RGELKLDQHVKVEPSDFARSSPVRDKYPGGTLTIAELLRYTICESDGSTSDVLMKLIGGP -AKVMLFLEGIHVSDIQVVNYEKEIGRDWETQYRNWATPKGALALLAALQSQRGLSRESQG -LLLKLMTEAIPGAKRLKGELPAGTVVAHKTGTGGTQATNDIGIITLPDGRHLAVAAFVSD -SAADDN----------------- ->[subseq from] class A beta-lactamase n=1 Tax=Prevotella paludivivens TaxID=185294 RepID=UPI00036B1219 ---TIKDKINNVINNKNAGIGVAILDLNSNESV-VINGEEHYPMQSVFKFPIALKVLNDVD -NDKIKLSDSIFISSAELKKWSTIQEKYPNGNMALSDIIYYMVAISDNIGCDVILKNNGGA -SSINHYLRSIGVNNMTIKINEAEQQAKPDKQFQNWATPNEAINLLTMFYKHSLLKPATQN -FLWDTMKKTATG--SIKNKLPKGITVIHKTGSAPTAVNNDIGIMVFPNKKAVAYAIFIKD -SKETSDTNYNIIAEIGKIIAE-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas mossii TaxID=163665 RepID=A0A4Y9ILP3_9BACT ----LRNKIQKIIQGKDATVGVAII-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN -KNNLTLDHQLYVKKGDLLPHSPLRDDYPQGELSVADIIRYTVSKSDNNGCDILFRLVGGT -AVVDRYIRGLGLSEFAIAATEEEMHGPWEVQYTNWSTPYTAAQALEIFRTHDILPQPFHD -FLWDALAGTTTGGNKIKALLPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD -SMESNDVNCGIIAQISKAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 213 TaxID=2014530 RepID=A0A235IGX3_9NOSO ---SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDAIAGGSGTLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI -EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD -LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYEEf ->[subseq from] Serine hydrolase n=1 Tax=Rhodanobacter sp. C06 TaxID=1945854 RepID=A0A1V3PC73_9GAMM -haALQGKLDALSRRTPGVFGIVVLDPRSGERW-RVNADRAYPMMSVFKAPVAAAVFAQID -SGKLSMERAITLTRADIVGGSPSIGAHFHGGFTVRQLLAAAVSDSDNTAVDALLKLV-PP -QDVTAFLRAHGIAGMRVDMGEAGVDGAYLADPRNRSTPDAAADFLRQLQHGTLLSPSSTR -ALLALLQAQTQ-PDRMRQGLPHDVQLADKCGTSYTAAYNDIGILTWPDGRSVIVAAFLTA -STGSKAQREALFADLARTIAD-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A0Q4R3P9_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAQVARAIYDRf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI0006FB97B7 ----WQQVVENVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRENNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' N6 TaxID=1261031 RepID=UPI000CF31DC1 ---SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDAIAGGSGTLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI -EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD -LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYEEf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4X676_BREBE ----WQQAVENVLKEAPGIFGIAAMHLETGETV-GHLDEELFQLASAFKIPIMVTMMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIAITALSR -GVTDKESAELTIARVAKAIYE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas oligophenolica TaxID=301154 RepID=A0A502CMZ7_9SPHN ------------------------------------------------------------- ---------------------------------SAAKVMELMIVRSDNHAADQVLATLGGP -VALQRWLSSQGMTGIRVDRTIAQLLRGHLADSRDVATPVAMVTLLRKLDNGTVLTAQSRT -FLLELMSRCATGTRRIRALLPTGTQVEDKTGTLD-GITNDVGIITMPDGHRVAIAVFARG -GR----DRQPVIAEVSRAIYDRf ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. DC-2 TaxID=1303256 RepID=UPI0004C46C77 ------------------------------------------------------------- ----------------------------LGTPLPVTALLELMLTRSDNEATDVLVARAGGP -QAINSWLQSIGIHGQRVDSNTAQLLEAFAADPRDTSTPRAMNDLLAAIHHGKALKPGSSA -ALLAIMARCKTGKARLTGMLPPGTQIAHKTGTLN-GLGNDAGLIALPDGRTFAISVFVMK -DHRGHVLRDRIMAEVARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A031JEL1_SPHPI ----LLGEFERFAALTDGTVGIAVSDLHSGQSI-GINNDTLFPMASTYKVAVAGKIFSMAD -AGALNLDERLP---------------RLGTPLPVTALLELMLTRSDNEATDVLVARAGGP -QAINSWLQSIGIHGQRVDSNTAQLLEAFAADPRDTSTPRAMNDLLAAIHHGKALKPGSSA -ALLAIMARCKTGKARLTGMLPPGTQIAHKTGTLN-GLGNDAGLIALPDGRTFAISVFVMK -DHRGHVLRDRIMAEVARAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Legionella gratiana TaxID=45066 RepID=A0A378JN91_9GAMM ---ELSKRINVIEKNSHTVMGITAIHIEKNKII-SHNSNQRFFMASTVKLPIALAFLHRVD -EKKDSLNRIIKMDTKNSVPGSGSLHHLFEKKMSLKQVLIHMMRNSDNSASDTILKVANGP -KYVASRMNALGFKNISVNRSILEMFLRFQNDTRDTTTSDDMAKLLVKLYKKQALSESNTK -LLIDIMEKCRTGRSRIKGLLPAHVKVAHKTGTWSYRFVSDVGIITLPNNGHIALAVYVKS -QSASDYPRSRAIALASRAIYDHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonadaceae bacterium KCTC 52780 TaxID=2172047 RepID=UPI000E0D47A2 --qSLEQRLAALATENPGEYGIAALDLQTGAMV-SFNGNEPFPMASTMKIAVAAAYLEEVD -AGRRSLADEI-------------------GGVTVHSLMDSMITRSNNRATDILMNALGGP -AAIDGWLRRHRLTGIRVDRTIAQLLADRRRDIRDSSTPEAMLGLLRLIASGDALSTNSRA -LLLDMMRRCATGSNRIRGLLPPGAQVAHKTGTLN-GYTGDVGYFTTPEGRRIAVVFFARY -GE----NRPAVISTAARAIYDAf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A414LIV0_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLKDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDTDNAAIIASISKIVHD-- ->[subseq from] Beta-lactamase n=8 Tax=Bacteroides TaxID=816 RepID=B6VZN3_9BACE ----LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. M41 TaxID=1806885 RepID=A0A127MGN2_9SPHN ---ALVREIDQLWRTFPGKTGIAVKRIDGGWEF-GHRSDEYFPQQSVSKLWVAMAMLDKID -QGRASLSDPIRIGKEDLTVHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP -DAVRRFIAKNSLGKIRFGPGERLLQSAYLADPVDGASPIAIVRALDKLARGELLSDNSTK -LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMMGD -TTASIPERMRMMQAVTRAVARY- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WQP1_9BACT ---ELTKLLRSLCDAVAGDIGVAVVHVESGKIV-TVAGDKKLPLYSVYKLPLAITVLREIE -AGKLRLDQKVKVNPADIAGVQFNTDLWRGTQKTVRELIEYAIVRSDNTSADKLLGLIGGP -PIVTQQMRTIGLANIDVVVTSREFTAH--RDKPNTGTTTDLAQLLARLQKGELLQPAKVS -LLRDYMERSKTGERRLRANLPAGTQVADKTGTGDV-ATNDVGLITLPNKGHLAIAVLISG -SKLPVDKQEKTIADIARAAYDSf ->[subseq from] Beta-lactamase class A n=2 Tax=Bacillus oleivorans TaxID=1448271 RepID=A0A285CJJ8_9BACI ----LQQMLNEIVQSSSGTYGVAVKHLDTGEFA-GVNQHERFQLASTFKIPILVTLFRDVN -SDKLELEDIVTVQEEDIVIGSGVIQHHPRVQFTIKDLATLMIIVSDNLATDLILKLV-GT -ENVTSYMKELGLSNTFIHFSCRQLLNFQGDSRNNVSTPVEMAMLVEKIARKEIISEKSCD -AMLDILLKQQF-NSRLPYLLPSRTKVAHKTGTIGN-VINDVGIVYLPEGGAFSIAVLSKE -SV-SMEEGERTIGRIAKAAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. LC81 TaxID=1502850 RepID=A0A095CZ57_9SPHN ----LNDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGAELFPQQSVSKLWVTLTVLDAVD -QGRMTMDQRVRIGPEDLTLHQPIAARVRAEGMSVRDLIETAITHSDNTANDSLLRTVGGP -SAVRAFVAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS -TTSGIPARMALMQSVSSAVAEY- ->[subseq from] Class A beta-lactamase n=1 Tax=hydrothermal vent metagenome TaxID=652676 RepID=A0A3B0TAD0_9ZZZZ ---ALVHEIADLWRTFPGKTGIAVKRIDGAWEI-GHRANQSFPQQSVSKLWVAMTMLDKID -QGRASLSDAIRIGPEDLTLHQPLAAEVRREGKSVYTLLEKALAHSDNTANDALLRHAGGP -EAVNRFIQRSKLGRIKFGPGERKMQSAYLADPIDGASPSAIVNALDKLARGELLSQNSTR -LLLSILSRTRSGPNRLKAGVPSGWKFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGD -TTAPVPERMRMMQAVTRAVARY- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T5E5_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLEHLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroidetes bacterium HGW-Bacteroidetes-20 TaxID=2013689 RepID=A0A2N2XYZ5_9BACT ---ALNDTIGKIISNKKATVGVVVAN-KNGIIVaEKNGAQHFPMQSVFKFHIAIVMLSEIE -KGKFTLDQPIEIKKSDLQVWSPIRDKYPNGTLTIREIIQYTVSQSDNNGCDILLQLLGGP -KVVENFFKEKRFSDISIQINEAQMHTKWNEQFKNWITPYTSNAILFQFNMQTFLTPIHKT -FLLETMINTTTGMGRLKGLLPPSAVVAHKTGSSGTAAANDIGIVFVDKENWYVISVFVTQ -SSENEVVNDQIIAEISKAVWDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346TJ64_KLEPN ------------------------------------------------------------- ----GLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVGDKTGTCGYGTANDLAVV---------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Gloeocapsopsis sp. AAB1 = 1H9 TaxID=1433147 RepID=UPI000CF6A175 ---SLKTTVEQLAAQKNLLPGVFFVDLDSGSYL-DINGSSNFASASMIKVPILVAFFQDVD -AGKIRLDESLTLKKELIGGGSGDMQKPLETKFTALETATKMITISDNTATNLLIERMGGI -AALNQRFLSWGLTATQIRNLLPDLEGT------NTTNPKDLAHLMALVNQGDLMSLRSRD -RLLDIMRRTVT-NTLLPRGLGEGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIAVAMVKR -PHND-GRAQELIRQISRAAYQEf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0005E2E40D ----------------------------------------------TSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CC-3A-396 TaxID=2135655 RepID=A0A4R2UKR5_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -AAIQQWLLSLQIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNKLDNGSVLTAQSRN -FLFELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] Beta-lactamase n=1 Tax=Dolichospermum planctonicum TaxID=136072 RepID=A0A480AI97_9CYAN ----LKNTLQSLAANSDLTPGVFLLDLDNGAYV-DINGNTSFPAASTIKIPILIAFFQDVD -AGKIRLDEMLTLEKEMIVGGSGNMQYQAPGGYTALDLATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSARELGNLISMVNQGNVVTMRSRD -SMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR -PNND-PRAEKLISSISSSAYQYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf242 TaxID=1736304 RepID=UPI0009EA4889 ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAQVARAIYDRf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-F2F-G114-C0414 TaxID=2135662 RepID=A0A3M0EC68_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAQVARAIYDRf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-3A-406 TaxID=2135659 RepID=A0A3M0FQN5_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAQVARAIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. LK11 TaxID=1390395 RepID=A0A1P8PQY4_9SPHN ---ELVSTINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP -QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQQLIQNVAAAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=R9I1T0_9BACE --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ -KQHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDPMKNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVTLPDGSRYVVAVFVKD -SKENMETNTKIISDISTAVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Sphaerospermopsis kisseleviana NIES-73 TaxID=1973480 RepID=A0A1Z4UK18_9CYAN ---TLKSTLQNLATANSLTPGVFMVDLDTGDYV-DINASTSFPAASTIKIPILVAFFQDVD -GGKIRLDEMLTMEKEMVAGGSGNLRTPVGSKYTALDVATKMMTISDNTATNMLITRLGGQ -EVLNGRFRSWGLTTTAIRNILPDLEGT------NTTSPKELADLIAKVNQGNLVSMRSRD -LMLDIMRRTER-NTLIPSGLGEGARAYHKTGDIGT-MLGDAGLIDIPTGKRYIAAVMVKR -PHND-SAAETLISSISKAAYENf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Prevotella sp. 10(H) TaxID=1158294 RepID=UPI0004A70B17 ---KLRKEISGIIGGKDAKVGVALI-VDGKDTL-TVNNNFHYPTQSVYKFHLALAVLDYLD -KNNMTLDHKISVKKSDLLPHSPLRDDYPEGNLSVGEILRYTVSLSDNNGCDILFRFIGGT -DVADKYIRNLGMTDFAIAATEEEMHGPWEVQYTNWSTPYTATLVLEKFRTGNILPQPFHD -FLWSIMTDSPTGKNKIKALLPEGTVVAHKTGSSFNAAENDIAIVQLPDGRCYSLAVFVAD -SMESSYVNCKMIADISKAVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2ZM28_9BACL ----WQQAVENVLKEAPGIFGIAAVHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -DVIDKEAAELTIARVAKAIYE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. JUb134 TaxID=2485112 RepID=A0A4V2TJV2_9SPHN ---DLTRAITTLLANFNGTAAAAVTSIDQGWTV-AYNGNRPMPQQSVSKLWVAMTALDLLD -QGKLTLDDPVVVRREDLTLHQPIASLVKGDGTTVRELMRRALTMSDNTANDRLLTYVGGP -NAVRAFLARRGIQNIRFGPGERLLQSAYVANPPDGAGATAIAEALMRLKQGKLLSANSTR -YLLDTMAASRTGRARLHAALPPGWTLAHKTGTGQNAGFNDVGILTAPDGRSYAVAVLIGD -TRAPMRDRQQLIQQVVHALV--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas oligophenolica TaxID=301154 RepID=A0A502CCM5_9SPHN ---QLTSAIDALARGFSGKFGIAVRAVDEGWTV-EETARQRLPQQSVSKLWVAITLLDLRD -QGKARLDDPIVVRPEDLTLHQPIAGLVKGDGTTVGDLLTRALTHSDNTANDRLLSYVGGP -QAVRAMIERKQLGDIRFGPGERLLQSAYTADPPDGAAPIAIADALARLARGEVLSETSTR -IMLDTMGNSVTGRARLRAALPGGWGIAHKTGTGQNAGFNDVGLITAPDGRRYTIAVMIGD -TRESVRSRQQLIQAVANAVAT-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=UPI0012313728 ----LKADFDKLLQDKQATVGVAVVS-DGRKTF-TYNNQHHFPLMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas sp. 3F27F9 TaxID=2502209 RepID=UPI0010F54884 ---ALVANVAALVRGFDGRVGVAVRSIEEGWAV-DTGGEQRLPQQSVSKLWVAMTVLDYRD -AGRLKLEDPITLTRDDLTVHQPIAALIKGEQTTVGELLQRALTMSDNTANDRLLRYVGGP -NAVRDFLQRKRLGDIRFGPGERLLQSRYVSDPPDGAAPRAIAEALARLKRGDLLSRSSTE -YLLATMESSHTGKQRLRGAVPAGWTFGHKTGTGQTAGYNDVGLLIAPDGRSYAIAVMIGD -TPKPIPARQALMQAVVASVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TF3 TaxID=2495580 RepID=A0A432VGN4_9SPHN ---ALVANVAALVRGFDGRVGVAVRSIEEGWAV-DTGGEQRLPQQSVSKLWVAMTVLDYRD -AGRLKLEDPITLTRDDLTVHQPIAALIKGEQTTVGELLQRALTMSDNTANDRLLRYVGGP -NAVRDFLQRKRLGDIRFGPGERLLQSRYVSDPPDGAAPRAIAEALARLKRGDLLSRSSTE -YLLATMESSHTGKQRLRGAVPAGWTFGHKTGTGQTAGYNDVGLLIAPDGRSYAIAVMIGD -TPKPIPARQALMQAVVASVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MMX4_BREBE ----WQQAVENVLREAPGIFGIAAVHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLRWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEDSCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Mal48 TaxID=2527994 RepID=A0A517QJN9_9BACT ----LKDSLTSLVESFEGEAGVAVKHIPSGETV-LINADEAMPTASLIKISVMIEAYRQVE -AGKLDLAALITLKKEDKVPGSGVLTTHFSPGLSLRDAIRLMMAYSDNTATNLVIDQV-GL -KSVSDTMEELGFPETKIHSKVYRGSTRSKKYGLGSTTARETMNILEKLSQSEFTNEKFNK -EMLEHMRKCIN-RDRIPPFLPRRTVVAQKTGSIST-ARTVAGIIESPSG-PIIVVVLTAK -GNRDGKTTDMLMASISKRAFDYf ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium zucineum TaxID=284016 RepID=A0A2W5NUA5_9CAUL ------------ARARPGVLGVGLANLESGQVY-LFNGERRFPMQSVFKLPLAMAALAEVD -AGRALLTERIQILEEQLSAYSPIGAAWPARRFTFRELLEAVLVESDNTAADVLMKRIGGP -GAITAWLDARRVPEVRVDRYERELQCRYLADPRDTATPRGMIEFLRMLDQDELAEPQSTR -LAMGLMARTPRAPNRIRAGLPRDAFLAHRPGTAGSAAHNDVGIFRLADKRAYALAVFLSG -ATLDEAGRDTVIAEVARAAVA-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. TaxID=29523 RepID=A0A3C0E2M8_9BACE --qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGDYCK -RHQISFDTLLTVDSTDLQPYSPLRDQYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTQTLFDKPHQE -FIKEALVTCQTGTNRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQLPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium 24-56-14 TaxID=1970588 RepID=A0A258Z7V6_9SPHN ----LENLIQDQWRLFPGRTGVAIMRVDGGEWVlGRRMDELFPQQSVSKTWVALTVLDMVD -QGKLRLDQKVRITRDDLAVHQPIRDQVIANGVSVLNLLETSIRASDNTANDSLLRTVGGP -QAVKSFIARKNLGAIRFGPGERALQSRYLNDPIDGASPQAIVRALAKLAKGELLSASSTR -LMLDIMSRTSSGPNRLKAGVPAGWSFLHKTGTGQSTGYNDIGIMTAPDGTRYAIAVMMGS -TTASIPQRMTFMQFVSRTVASY- ->[subseq from] Uncharacterized protein n=2 Tax=Planktothricoides sp. SR001 TaxID=1705388 RepID=A0A0M1JWI4_9CYAN ---QLKNEIQTLSASYQLTPGVFFVDLDTGAYL-DMNGNNTFSAASTIKVPILIALFQEVD -AGKIRLDEPLTMQAEYVAEGSGDMQDPVGTQYTVLETARKMITISDNTATNMLIARLGGQ -NVLNQRFQSWGLASTQIQNFLPDIQGT------NTTSPKDLVSLMAMVEKGGLLSLRSRD -RVLDIMQATEN-NSLLPQGLGDDATIAHKTGNIGS-VLADTGIVDLPNGKRYLASVIVKR -PH-DDPGASELIRQISQAAYQSf ->[subseq from] Beta-lactamase n=4 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A174WNU4_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPASLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Tannerella sp. AM09-19 TaxID=2293249 RepID=UPI000EFDB684 --rELKMRIASVLKEKRAIVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH -KNNLSLDTDIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT -KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNMATPSSAVLLLDKFLKEDLFRDEYGS -YLRKIMIETSTGNDKIKAGLPEGVVMGHKTGSSDRNGDNDLAFVQLPDGQRYCIAVFIRN -SKEDDKTNAAIIASVSKVVYDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Oceanobacillus oncorhynchi TaxID=545501 RepID=A0A2L0NGV8_9BACI ------------------------------KILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGEL------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A5C7M6M3_9GAMM ---DFEARLYNAADGSNGRIGVAVIDLGTGRTV-SVLGDTPFPMASTSKIAVASTFLDGVD -KGKWTLDDKFPLMIPVGSAFSGSKAPRPGEMLTARRLIELALINSSNPATDALLAAVGGP -AAVNRWIKTTGVEGMRIDRDIATLVRARTVDLRDSAPPVARAQLLAGLFQGQWLSQRSRA -FLRGTMERCVTGKRRMRALLPSDARIAHKTGTLNN-TASDVGIIQAPDGHAYAVAIYVTG -QG-GKPNRDARIASIARTIYQ-- ->[subseq from] serine hydrolase n=1 Tax=Sphingopyxis sp. Z10-6 TaxID=2484145 RepID=UPI0014485D00 ----LAERINFLWRGFPGKTGIAVQRIDGEWAI-AERGGELFPQQSVSKLWVALTALDAVD -QGRVRLDQQVRIGPEDLTLYQPLAARVRAQGMTLRQLIETAITQSDNTANDSVLRTVGGP -GAVRAYMAKKDLGAIRFGPGERLLQSNYLANPIDGASPTAIASALTRLARGTLLSPESTE -YLLDVMSRTKSGPKRLKAGLPPGWKFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TTSPIPARMALMQAVSSAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. AG363 TaxID=2183997 RepID=A0A420CVM1_9FLAO ---DLKKTIESIISNKKADVGVSIIDPYHKERI-QINGNKLYPMLSTVKFPIALTVLNKIE -KGELSLQQKLLIKKEELLEWSPFRKEYPDGNISLEEAIKWMVSYSDNNLTDILLRLIGGP -EPVQQFINS---KDFIIRNNEEDMHKDWESQFVNKITPNETTKLLEAFNNGKILNKKHTL -WLYNAILNNTTGTKRLKGNLPQHVKTAHRTGTSFTGAVNDFGIIEISGKKKFYIAVFIHD -TYEKFGDAEAIIADISKAAYEYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147J645_9SPHN ---ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -QGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP -QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPAGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Taibaiella chishuiensis TaxID=1434707 RepID=A0A2P8CZH8_9BACT --tALEQQIGQITAGKKAEIGIAIIGPAPGDQV-MIHAAPLYPMLSTFKFPVALTVLHQVE -QGKLSLNQQIFIRKEELLDWSPFKEKYPKGDITLADALTWMMCYSDNNITDILLRLIGGT -TPVQQFI---GGNDFVIRNNEEEMHANWDAQFVNRISPARAAQLLNQFQQGKLLHKKHTR -WLYKAMLGNKTGLKRLKGKLPPTVKVAHRSGTSFTGAINSFGIIELPGGKRIVIAVLIRD -TYESFDDTETIIADIAKTTYDFy ->[subseq from] Class A beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A4Q3VWV3_9BACT ---DLAQQIRAIEAQFGARLGVAAQRF-GGPRF-DYRGEERFPLQSVFKLPLAVVVLRAVD -AGKLRLDDSVTLSKANISVYSPLSERVWATGTTWADLIRASVSKSDNTAADVLMRRIGGP -TTTTANLHALGAQGLRIDRYESRLQCRALSEVRDSSTPKGMLTFLRGYETAGWLSTRSKE -FLDRALFETTTGPDRLKAGFGPGWKLRHKTGTGGYGARNDVGIATDKVGSKVAIAVFFSG -AVGSDKTRDAAIAKVARLVR--- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Muricauda pacifica TaxID=1080225 RepID=A0A2T0MBA4_9FLAO ---RLKQEIEQVVEGKLATVAVSIQGMEPQETL-SVNGNLHLPMQSVFKLHLAAAVLNEID -KGKLGINDSIKLTPELILEWSPLRKKYPKGGVQIEELLKYNVAWSDNVGCDVLLDLIGGP -IAVQNYIHGLGVKDIAIIDKEIFLQSDWSRQYLNWSTTNASNSLLQILYEQNILSASSHQ -FLMATLKETSTGKGKIRGQLPKDAVVAHKTGSSGTGATNDIGIVFLPDNRYFYISIFVSD -SKEDEVTNQKMMADITKLAWDYf ->[subseq from] Serine hydrolase n=1 Tax=Sporanaerobacter sp. JN28 TaxID=2507161 RepID=A0A410QCW4_9FIRM ----LENKIREFIKNQKGNVAVAIKDLKTGKEI-KINENLVFPSASTIKLSIMSELFNRVN -MRSLNLNDKIKLTENMKTGGDGILKEELGHKFTLKEIMTLMIIISDNMATNILIDLL-GM -DNINKRIKDMGLKNTRLQRKMMDSQAA-KEGRENLTTANDLCLILELIYRGKNINEECSR -MMLDILKRQQV-RGRLDLYLPEDVIIAHKTGDLDC-LEHDVGIVYLPHRE-YIICVLTNE -TE-TNKDGREIIGKVSKMVYDEf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. HY039 TaxID=2501476 RepID=UPI000FEBEBB0 ---PLEKTINSIIKNKKATVGVAVIY-DGRDTL-TVNNNYHYPTMSVFKFHQSLAVLDYMD -KNLLPLETPLFLKKSDLRPYSPLRDERPEGNISIGELVKYTVAKSDNNTSNALFHYMSGT -RMTDLYIRTLGIKDFAITATEAEMSDDFNNQYLNWTTPLAAARLLEVFLKDDLVSKDTRD -FLVNAMVQTTTGPDKLKALLPATTKIGHKTGSSARSADNDIGFVVLPNGKQYSIAVFVMN -SMESDKTNARIIADISKAVYDFy ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A430E140_9SPHN ----LVSAINALGGGFQGKVGIAVRSIDDGWVV-GHAMDERMPQQSVSKLWVALTVMNAVD -EGRLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVSDPPDGAGAGAIADALARLHHGMLLTPQSTS -WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD -TSRPVPERQQLIQTVVSSIV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Coprobacter fastidiosus NSB1 TaxID=1349822 RepID=A0A495VQ65_9BACT --rELKMRIASVLKERKATVGIAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH -KNNLSLDTEIFIRESDLLPYSPLRDRHPQGNMSIQELLSYTVSLSDNNACDILFGYIGGT -KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLFRDEYGN -YLRKIMIETSTGNDKIKAGLPERVVMGHKTGSSDRNGDNDLAFVQLPDGQCYCIAVFIRD -SKEDDKTNAAIIASVSKVVYDY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Gabonibacter massiliensis TaxID=1720195 RepID=UPI00073EE5AA -heNLQKQLRETIAGKNAQVGIAVI-LNGKDTI-TVNNDCQYPMMSVFKLYQALAVADYCQ -KEKLSFETSVYIRRSDLKSYSPLRDRYPQGELPIKELLKYTLHLSDNNACDILFARTGGT -EATDKYIRSLGIRDFSVEFTEDEMHKDINTCYRNWSTPLEAVKVMELLLTRPLFDKDYQD -FIKQAMVTCETGKDRLPFPLETEAIIGHKTGTGDKGGINDVGFVYLPNGKRYTIAVFIKD -SAENMQESSRIIADISRVVYQY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella sp. GL-C-18 TaxID=2116704 RepID=A0A2P7QJJ8_9SPHN ------------------------------------------------------------- -------------------------------GVSARTLMDQMITRSDNRATDLLIAELGGP -QVIDNWMRSHGLSGIRVDRTIAQLLSARRRDVRDSSTPTAMLSLLRTVDGPRALTPASRS -LLLDMMSRCHTGRNRMRALLPAGTRVEHKTGTLN-GYTGDVGFVTLPDGRRIAVALFARG -GV----NRPAVIATAARTIYDAf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A223ZX98_SHISO ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGT----------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Agromyces sp. MMS17-SY077 TaxID=2662446 RepID=UPI001326E91C ---RMTRDIAAIERRTGVTIGVAMSGAARRDSF-AYRATETFPMCSLFKVLAAAALIEARA -CDEEYWTTPQPVG--TVVEDSQVFEGLTEA--TPELAADAALRFSDNTAGNYLLRELGGP -AAIGAFAARFGARSTRLDRWEPELNEATPGDPRDTTTPADIARVYRALVLEDAAGVLVGS -RLRAWMLRNRTSDARMRAGLDRPYDLADKTGGGSYGVVNDAGVLWRPGESTRTIAILTRR -TDPEAPRDNTVVAEVTRILT--- ->[subseq from] Beta-lactamase n=1 Tax=Alistipes inops TaxID=1501391 RepID=A0A0B0BZC1_9BACT --tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD -RNGLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP -TAADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE -FIIRTMTGCNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGRHYTIAVFVKD -SQESLQETERIIAEASDIVYRY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas desiccabilis TaxID=429134 RepID=A0A4Q2IR14_9SPHN ---DLTRAITTLLANFNGTAAAAVTSIDQGWTV-AYNGNRPMPQQSVSKLWVAMTALDLLD -QGKLTLEDPVVVRREDLTLHQPIASLVKGDGTTVRELMRRALTMSDNTANDRLLTYVGGP -DAVRAFLTRRGIQNIRFGPGERLLQSAYVANPPDGAGATAIAEALMRLKQGKLLSPGSTR -HMLDTMAASRTGRARLHAALPPGWTLAHKTGTGQNAGFNDVGILTAPDGRSYAVAVLIGD -TTAPMRQRQELIQQVVHALV--- ->[subseq from] class A beta-lactamase n=1 Tax=Methylobacterium sp. B34 TaxID=95563 RepID=UPI0005B2B01C ------------------------------------------------------------- -----------------------------GPGISVANLCAATLIWSDNTAANLFLADLGRP -EALTAWLRTTGDPVTRLDRTEPTLNTALPGDPRDTTTPDAMRATLGRVLLGTVLSPASRA -RLEAWMVACETGRKRLRAGLPPGWIAGDKTGSGDNGTVNDVAILRPPGRAPILAAVYVTE -STASPDTCAAAYAEIGRLIA--- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. 17J27-24 TaxID=2555898 RepID=A0A4Y8ZQC2_9SPHN --rALAAQIRALGQAFNGDIGIAVRDVQTGWAT-AYDGNTYFPQQSVSKFWVALTALDKVD -QGALSLTRPVTLTKADMTLHQPIARQIGASGTNIGTLMTRALQQSDNTCNDAVLWRAGGP -EAVRAFLREKGISGIRFGPGERLLQSKYIASPMDGATPLGVVDALARLKRGELLSPASTE -RLLSIMSHTKTGPQRLKGGLAPGWQLAHKTGTGQQAGYNDIGVITAPDGHAYAIAVLIRR -TSAPLGERMAAMQKTVRATI--- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A TaxID=2014529 RepID=A0A235I8J2_9NOSO ---SLKNAVQNLAATNNLTPGIFLVDLDTGNYV-DINASTSFPAASTIKVPILIAFFQDVD -AGKIRLDDMLTMQQDMVAGGSGDLQKPPGTQYAALEVVTKMITISDNTATNMLIARLGGM -DALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DTLLPSGLGTGARSYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PAN-DPRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A4Y3PWR2_BREPA ----WQQALDEALKDAPGVFGVAALHVETKEEA-GHLDDELFQLASAFKIPILVTLMREVE -AGRVALDQRIASQKENRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLVIELIGGI -DKVEAHMHELGLEQIHLRHTCWQLLNSLPTRDNNVATPRDLNRLLAMIARKEILTPASCE -LMLDILRRQQF-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPDKGAIAITVLSRA -VT-EKPAAELAIARIARAIYDQ- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=UPI0009E8DF17 ---ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -QGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP -QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPAGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] class A beta-lactamase n=1 Tax=Novosphingobium rosa TaxID=76978 RepID=UPI0009FBFD2B -----------------GTLGFYLLDTATGQGF-GERMDERFAMCSSFKLSLAAHVLHLAQ -QGRIDLTQNVTYGEAFVAAHTPDTKAHLSTGMSVLDLARVSVVNSDNAAANLLLERTGGP -EALTAFWRALGDTFTRLDANEPSLNRVPLGEVRNTSTPRAMAHTVATLLTGPLLTAPHRT -LLLDWMHESATGLKRIRAGVPQGWWAGDKTGTASYDNCIDLA------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Dolichospermum circinale TaxID=109265 RepID=UPI000411439C ----LKDTLQSLATNSDLTPGVFLLDLDNGAYV-DINGNRSFPAASTIKIPILMAFFQDVD -AGKIRLDEILTLEKEMIVGGSGNIQQAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ -EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD -SMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSSAYQYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium 13_1_40CM_4_58_4 TaxID=1803453 RepID=A0A1Q7KMF3_9BACT --qKLESTFDDVDQNLDGVLGVAVLDLTTGQKF-LLHADEVFPQASSIKIAVLAEFYHQAR -SGKLKLTDLYTVQSSDLVPDSYIMAGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-SM -ENVNALMDSLGLAHTRLRRKMMDLKAAG-EGRENISTPREMMTLLEDLYRGKVLNKEMTD -DFFKVLSTEKK-DSFIPRDLPEGLKVANKHGELE-GVRNDSGVVFLQNR-PYVICVMTTY -LRR-ERDGEEAISKISLTAYRIf ->[subseq from] Class A beta-lactamase n=1 Tax=Alistipes sp. 56_11 TaxID=1896968 RepID=A0A1Q6ECW9_9BACT --tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD -RNGLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP -TAADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE -FIIRTMTGCNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGQHYTIAVFVKD -SQESLQETERIIAEASDIVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2X3H3Y8_KLEPN ------EQIKQSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTHYPGQHG------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. HMF7854 TaxID=2315330 RepID=A0A3R9Z507_9SPHN ---DLQAQLRALAVAQPGGAGIAAIDLATGREI-SVDGDRPFPLASTVKLLVAATYLDAVD -QGRRSLAEPIPFDERWRHHGLMTVLAHPGVTLSAANWIEAMLTQSDNSAADQMFAAVGGP -AAVQRWATAHGVAGVRVDRDIGGILLRFAADPRDQGSALGMARLLARIDRGELLRPASRA -WLLDVLGRTRTGPDRIAAGLPAGARLAHKTGSLR-GVTDDVGIATLPGGRRIAIAVLASG -PASDGKARAALIAAAARAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Tannerella sp. CAG:118 TaxID=1262978 RepID=R5I3Z5_9BACT --dELRKELETVIRDKKARVGVAVIY-DGKDTL-TLNNEYRYPMMSVFKFHQALSVLNDLD -SRGLPLDTEIFVKKSDLHPYSPLRDSVPQGNMTVAELLRYSITLSDNNACDILFKHFGGT -DRTEKYMKGLGIEKIVIQSDENEMHTSVDAERANWTTPLEAAKVMDIFLRNKLFPISLSD -FLENLLICTSTGADKIKGGLPSGVIMGHKTGSSSRTADNDLAFVQLPDGKRYTIAVFVMD -ADEDDKTIAGIISQISRHVYDFy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF17-1 TaxID=2292919 RepID=A0A3A6LVQ3_9BACE ----LKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas guangdongensis TaxID=1141890 RepID=A0A285QGZ1_9SPHN ----LKETIGALRNQFDGLAGIAVRSVDEGWAIeSVDADRRMPQQSVSKLWVAMTVLDAVD -RGRLGLDTPVRIRREDLTLHQPIASLVKADGATVRELLQRAMTQSDNTANDSLLRTVGGP -TAVRSFITRKGLGNIRFGPGERLLQARYVADPVDGAAPAAIAAALARLKRGDVLSSTSTD -YLIRTMESSKTGKYRLRGAVPPGWTFGHKTGTGQTAGYNDVGLLTAPDGRTYALAVMIGD -TRRPIQERQLLMQAVVAAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. FARSPH TaxID=2219696 RepID=A0A345WNN2_9SPHN ---QLVERIDRLAAGFDGKFGIAIRAVDEGWTVaSPGARTRMPQQSVSKLWVAMTLLDLRD -QGKARLDDPIVVRREDLTLHQPIAMLVKGDGTTVGELLRRALTMSDNTANDRLLTYVGGP -AAVRAMIERKQLGDIRFGPGERLLQAAYVNDPPDGAAPLAIADALARLARGELFTETSTR -ILLDTMGASITGRARLRSALPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQELIAGVAAAVADY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-1G-424 TaxID=2135658 RepID=A0A4R2RXL6_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -GAIQQWLSSQNITGIRMDRTIAQLLRGHLADSRDVATPVAMVTLLNKIDNGTVLTAQSRT -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAQVARAIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. PAMC28499 TaxID=2565554 RepID=A0A4V1CFY5_9SPHN ---HLLAEFDRFAALSDGTVGLAVQDLQTGEVQ-SRNGDTLFPMASAYKVAVAGRILSLVD -AGSLKLDDRLVLDPALASEGIAWMFSRPGATLPVSQLLDLMLTRSDNNATDVLVARAGGP -KAVSDFVAGLGIHGLRVDSDTAHLLYDFMLDPRDTATPLAMNQLLVAYESGKALKPESTQ -LLFTIMGHCQTGKLRLSGMLPPGTPVAHKTGSLN-GVGNDVGIIGLPDGRRFAITVFVMK -DSRGHVSRDQIMAQAARAAYDYf ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter algicida TaxID=1836209 RepID=UPI001325DC20 --tDLERRVASVADGSNGRIGVAAVDLSTGQMV-SVLGDQRFPMASTSKIAIAATFMQGVE -DGRWSLNDSFPMLYPVRSKSSKVAPVREGERLPATRLIELMITRSNNYAADALLRVVGGP -EAVDKWVHRAGISNFNMTRDILTLVRANHIDNRDSATPKAMVTLLAGLYQGRWLSADSRK -VILGAMSRTVTGRNRMKYLIPTDAKVLHKTGSLHD-TCSDVGLIETPDGRTLAVAVYVTG -QR-SRGAREQKIAMISRAIYDGy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. PP-F2F-A104-K0414 TaxID=2135661 RepID=A0A4R2TAS4_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMDLMIIRSDNQATDQLLAALGGP -AAIQQWLLSLQIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNKLDNGSVLTAQSRN -FLFELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. YJ09 TaxID=1104779 RepID=UPI0012D35C5A ---HLANRIDELGRGFSGRVGIAVKSIDDGWET-GWRDNDLYPQQSVSKLWVSITALDAAD -RGRIDLDDKVTLTRSDLTLHQPIAAEVLDDGTTLGDLMKRAITTSDNTANDRLMRAVGGA -SAVRAMIARKGLGSIRFANGERDMQSRYIADPYDGAAPSAIVDALASLKRGELLSRASTE -RLLDIMGHTRTGPNRLKGGLQPGWTLSHKTGTGQQAGYNDIGILTAPDGRSYAVAVMIKK -TSTPLRVRMTLMNNVVEAVIEQ- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. LK11 TaxID=1390395 RepID=UPI0009FA5D23 ---ELVSTINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP -QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQQLIQNVAAAVAN-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A6A1IUX0_9BACE --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKYHVGLTVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNITDKQILFGTQYKD -FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Uncharacterized protein n=1 Tax=Chlorogloeopsis fritschii PCC 6912 TaxID=211165 RepID=A0A3S0ZXD9_CHLFR ------TAVQSLVADNNLTPGVFVVDLDNGGYV-DVNASSSFPAASTIKIPILVAFFQDVD -SGKIRLDESLTMQKEMVVGGSGDMRKPVGTQFTALEVATKMMTISDNTATNMLITRMGGI -EALNQRFRSWGLTITTIRNPLPDLQGT------NTTSPKELGNLMAMVNQGNLVGMISRD -RILDIMRKTVR-NHLLPTGLGQGATIAHKTGDIGT-MLADAGLVDLPTNKRYIVAVMVKR -PNND-PRAEKLISSISRAAYQQ- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas melonis TaxID=152682 RepID=A0A0D1KQC9_9SPHN ---RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD -QGKARLDDPIVVREQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -QAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFSETSTR -ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQAVAAAVAN-- ->[subseq from] class A beta-lactamase n=1 Tax=Brevundimonas sp. Root1423 TaxID=1736462 RepID=UPI0009E73E23 ------AALEALADQTPGTLAACVVD-EAGASC--VNGDRPSSMQSVMKLLVGLAVLDAVE -RGELGLEDRVTLTRADVSVVQPIESRLGPSGTTIGELVRGAVIQSDSMATDWLIARLGGP -GAVQAFLERKGVTGIRLDRDERHLQTAYQQDVRDTATPRAMATLLYRLASGDLLGTSSTR -WMLATMKETQTFPDRLRAGTAPGWDAAHKTGTSNTGATNDVGVLTSPLGEPSGVAVFLAN -SPAEAPARAAAIAKVARIVTR-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Sphingorhabdus sp. SMR4y TaxID=2584094 RepID=A0A220WB64_9SPHN ---ALVREIDQLWRTFPGKTGIAIKRIDGEWEF-GHRIDEYFPQQSVSKLWVAMAMLDKID -KGRASLSDPIRITKDDLTLHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP -EAVRRFIDENDLGKIRFGPGERLLQAAYLADPVDGASPRAIVRALDKLARGELLSPNSTK -LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMLGD -TTASIPERMRMMQAVTRAVGR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SGJ3_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIVTSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Dolichospermum circinale TaxID=109265 RepID=UPI0004243CE6 ----LKDTLQSLATNSDLTPGVFLLDLDNGAYV-DINGNRSFPAASTIKIPILMAFFQDVD -AGKIRLDEILTLEKEMIVGGSGNIQQAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ -EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD -SMLNIMNRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSSAYQYf ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147IJI9_9SPHN ---ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP -QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Elizabethkingia anophelis 502 TaxID=1355388 RepID=T0PV66_9FLAO ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVFHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLVGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNNAHTQ -WLYNAMLNNVTGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRATWNYy ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZYJ5_9BACT ------------------------------------------------------------- --------------------------------MTLGALCAAAIEQSDNTAGNLLLDTIGGP -VGLTNFARSVSDETTRLDRKEPELNSAIPGDERDTTTPAAMCADMQRFLLGNVLSESSQN -QLQDWLRQNETGSLMIRASVPKTWTVGDKTGRCGNGATNDVAIIGPPGRAPILVAIYSIG -STSSADDRAAIVAEPARAVVE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas echinoides TaxID=59803 RepID=UPI00026CDB2B ---ALVANVAALVRAFDGRVGVAVRSIEEGWAV-DTGGEQRLPQQSVSKLWVAMTVLDFRD -AGRLKLEDPITLTRDDLTVHQPIAALIKGEQTTVGELLQRALTMSDNTANDRLLRYVGGP -NAVRDFLQRKRLGDIRFGPGERLLQSRYVADPPDGAAPRAIADALARLKRGDLLSRSSTE -YLLTTMESSHTGKQRLRGAVPAGWTFGHKTGTGQTAGYNDVGLLIAPDGRSYAIAVMIGD -TPKPIPARQALMQAVVASVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides dorei TaxID=357276 RepID=A0A5C6LAI9_9BACE --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] VEB-PER n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEL0_9BACT -------------------------------------------MQSTYKFHLALAVLGKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNLTTPDATIQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf9 TaxID=1735674 RepID=A0A0Q4CJ24_9SPHN ---ALVAAINALGDGFQGRVGIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGRYALDTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLAGGP -IAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAVADALARLHHGMLLSPTSTR -WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TSRPVQERQQLIQTVVSSIV--- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A1H7III0_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPMEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Uncharacterized protein n=1 Tax=Parasitella parasitica TaxID=35722 RepID=A0A0B7NNL7_9FUNG ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMP---------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sanguibacteroides justesenii TaxID=1547597 RepID=A0A0C3NCP8_9PORP -heNLQKRLRETIAGKNAQVGIAVI-LNGKDTI-TVNNDCQYPMMSVFKLYQALAVADYCQ -KEKLSFETSVYIRRSDLKSYSPLRDRYPQGELPIKELLKYTLHLSDNNACDILFARTGGT -EATDKYIRSLGIRDFSVEFTEDEMHKDINTCYRNWSTPLEAVKVMELLLTRPLFDKDYQD -FIKQAMVTCETGKDRLPFPLETEAIIGHKTGTGDKGGINDVGFVYLPNGKRYTIAVFIKD -SAENMQESSRIIADISRVVYQY- ->[subseq from] serine hydrolase n=1 Tax=Sphingosinicella sp. CPCC 101087 TaxID=2497754 RepID=UPI00101E0020 ------------------------------------------------------------- -------------------------------GATASSLLDSMITRSNNRATDLLMASLGGP -GAIDRWLRAHRLTGIRVDRTIAQLLSDRRRDIRDSSTPAAMIDLLRLIDSGDALSPSSRS -LLLDMMRRCATGSNRIRGLLPPSVQVAHKTGTLN-GYTGDVGFVTLPDGRRIAVVFFARG -GT----NRPAVISTAARAVYDTf ->[subseq from] class A beta-lactamase n=1 Tax=Rhodanobacter thiooxydans TaxID=416169 RepID=UPI0009D98406 ----LQMRLDALAQRAPGTLGIAVLDLRSGEAW-RVNARQAFPMMSVFKAPVAGAVLDRIE -HGGLSMELTVVIRRRELSSGT-IRDHFEGERFTVRQLLADAVSRSDNTAVDALLDTIGGP -RVVTAFLRSRGIDGMRVDLGERDFQSAYLVDPRNRSTPDAAAQFLRKLWEGQLLPPEPTR -HLLDLMYAQTT-PSRLRLGLPPGARLADKCGTSYTAAYNDIGILSWPDGHAIVVAAFLTA -SVDPKGERDALFADLARTVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Nostoc cycadae TaxID=246795 RepID=A0A2H6LGL0_9NOSO ---SLKNNIQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDVVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTSIKNQLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD -IMLDIMRRTER-DNLLPSGLGSGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR -PNND-PRAEKFISSISRTAYE-- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EB2DBB ---ALTTTIDALARDFGGVVGISVRSLEWGWQV-DANGDRRMPQQSVSKLWVAMTVLDARD -KGRLTLDDPVELTREHLTLHQPIATLVVRDGTTVRELLLRAMQQSDNTANDRLLNLVGGP -QAVRAFIADRGLGEIRFGPGERLLQASYVADPVDGAAPSAIALALARLKAGELLSASSTN -FLTTVMSGTRTGKARLRAAVPMGWTLAHKTGTGQTAGFNDIGILTAPDGKAYSVAVMIGD -TPRPVRERQALMQAVVASVVA-- ->[subseq from] Beta-lactamase family protein n=1 Tax=Sphingomonas sp. RIT328 TaxID=1470591 RepID=A0A031HQM0_9SPHN ---QLTSAIDALARDFDGKFGIAIRAVDGGWTVtSPGARTRLPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -AAVRAMIERKRLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFSETSTR -ILLDTMAASVTGRARLRAALPAGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIQERQRLIQSVAAAVAM-- ->[subseq from] serine hydrolase n=1 Tax=Sphingopyxis panaciterrae TaxID=363841 RepID=UPI001423F52C ----LSDRIAGLWRAFPGKTGIAVQRIDGEWAF-SERGDELFPQQSVSKLWVTMTVLDAVD -QGRLRLDQMVRIGPDDLAVHQPLAGRVLAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -DAVRRFVAKKDLGSIRFGPGERLLQSNYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLLGVMSRTKSGPKRLKAGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGS -TTSPIPARMSLMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=hydrothermal vent metagenome TaxID=652676 RepID=A0A160TNA0_9ZZZZ ---ALVANVTALGRNFNGRVGIAVRSIDQGWTV-SSNGDARLPQQSVSKLWVAMTVLDYRD -SGRLTLDDPITLTKDDFTLHQPIAALVKDGGTTIGELLRRALTMSDNTCNDRLLRYVGGP -AAVRDFIRRKGLGDIRFGPGEKLLQSRYVADPPDGAAPSAIAGALAKLKLGQLLSRQSTD -YLISTMESSKTGRQRMHGAVPAGWDFGHKTGTGQTAGYNDVGLLMAPDGRSYAVAIMIGD -TPRAIPERQALMQAVVTAVVA-- ->[subseq from] Beta-lactamase FAR-1 n=1 Tax=bacterium YEK0313 TaxID=1522316 RepID=A0A0A1PA92_9BACT ------------------------------------------------------------- -------------------PSSPITAPRAGAPLTVAEICEAAIVVSDNTAGNLLIEICGGP -ARLTRFIRTLGDSVTRLDRKLPELIVVAPDDPRDTTSPAAMGQNIHRLLLGDVLRPTSRA -QLTAWLVACRTGEARIRAGLPHGWRVGDKTGAGLAGETSDVGIIWPPGRPPVILSIYYVK -KDASGEARSAVIAEAAGLVA--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=A0A147IRD3_9SPHN ---ELVSTINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTYVGGP -QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELMSETSTR -ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQQLIQNVAAAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter sp. TaxID=1883446 RepID=A0A522H1E8_9GAMM ---ELQHSLNALAQRAPGVLGVDVLDLRSGIEV-QVNAHRAYPMMSVFKAPLAAAILSQID -SGQLASGQKVILKRADVVAGSAVPSIFHGEQFTVEQLLTATVSQSDNTAADALVKLAGGP -QAVTAFLRAHGIKGMRVDLDEAGLGRAFLGDPRNRSTPLAAVAFLRKLHNHELLSPTSTR -HLLRLLQAQTV-PRRLRAGLSSDIQLADKCGTSYTAAYNDIGILTWPDGHTVIVAAFLMG -SRASRAQRDALFADLARSIA--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. L-1-4w-11 TaxID=2572576 RepID=A0A4U1L5U9_9SPHN -------GIDAMVREFGGKVGVAIKSIDHGWMV-AKNGDDPMPQQSVSKLWVTMTLLDQVD -QGRVRLSDPITVTRADLTLHQPVASLLKNGVTTVGDLMRRAMTMSDNTANDRLLRHVGGP -AAVNAYIEKHNLGSIKFGPGERLLQSAYVADPIDGASAGAIANALTRLKRGELLSRASTA -HLIATMESSRTGRARLRATVPAGWRLGHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD -TSRPVPARQELMQAVVASVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas spermidinifaciens TaxID=1141889 RepID=A0A2A4B943_9SPHN ------TDIDRLVAGFGGKVGVAVKSIDAGWMV-SKNGDVPMPQQSVSKLWVTLTLLDQVD -QGRVRLDDPITITRSDLTLHQPIASLLKNGVTTVRELMRRAMTMSDNTANDRLLRHVGGP -SAVNAYIARHSLGAIKFGPGERLLQSSYVANPIDGAAAAAIANALTKLRRGELLSPASTA -YLIGVMESSRTGHARLRASVPPGWRLAHKTGTGQTAGFNDVGILTAPDGRAYSIAVMIGD -TSRPTQERQKLMQNVVARVVAY- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI0007518BFA ----LKKTLESIISGKKATVGISVIGPDTKEVT-GINGDQMMPMLSTVKFPLALTVLHEVE -KGKLSMAQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQKFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNVKILNKAHTQ -WLYDAMLNNVSGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHD -TYESFEASEKIISDIGRATYDYy ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0013CF6421 ----LKNAVQNLAANYNLAPGIFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM -EALNQRFRTWGLTTTTIRNSLPDLQGT------NTTSPKELANLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIST-MLADTGLIVVPTGKRYIATVMVQR -PEN-DPRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf34 TaxID=1736216 RepID=A0A0Q4KXC5_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMALMIIRSDNQATDQLLAALGGP -VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA -LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I4W7_9BACL ----WQQAVENELKEAPGIFGIAAVHLETGETA-GHLDEELFQLASTFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLPHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMQDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVNT-VVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Beta-lactamase n=1 Tax=Oscillatoria nigro-viridis PCC 7112 TaxID=179408 RepID=K9VLS5_9CYAN ----LKTQVQVLATENSLTAGIFLVDLDTGSYL-NFNGDTAFASASTIKVPILVAFFQAVD -EGKVQLDQMLTLKPEHIVGGSGEMQDSPGKKYSALEVAQKMIVVSDNTATNMMIELLGGA -EVLNQHFANWGLSTTVLRNKLPDLEGT------NTTSPKDLINIIAQVDRGNLVSVKSRD -RILQIMRQTRN-DSLLPKGLGEGSVIAHKTGNINT-MLADAGMVDLPNGKRYLVAVMVKH -PPETEKPAQALIREISRMSYRY- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A656ZTK9_BREPA ----WQKALEEALKDAPGVFGVAALHVETGEEA-GHLDDELFQLASAFKIPILVTLMREVE -EGRVALDQRIASQKENRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLVIELIGGI -DKVEAHMHELGLEQIYLRHTCWQLLNSAPTRDNNVATPRDLNRLLAMIERKEILTPSSCE -LMLDILRRQQF-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGGAIAITVLSRA -VT-EKPAAELAIARIARAIYDQ- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia anophelis TaxID=1117645 RepID=UPI000739969C ----LKKTLESIISGKRATVGISIMGPDTKEVT-RINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGH -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITPNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDESEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KKF6_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYGPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Calothrix rhizosoleniae TaxID=888997 RepID=UPI000B49DB16 ------------TKNTNLTPGIFLVDLDNGTYV-DINAAASFPAASTIKTPILVAFFQDVD -AGKIRLDEMLIMEQGMIAGGSGNMKKQPGTQFTALEVATKMMTISDNTATNMLIERMGGM -EILNQRFRSWGLRTTAIRNPLPDVEGT------NTTSPKELATLMAMVSKGNLVSMRSRD -RILDIMRRNTR-NHLLPVGLGKGAIIAHKTGNIGS-MLADAGLVDLPTGKRYLAAVMVQR -PRND-PSAAALIQSISRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Novosphingobium kunmingense TaxID=1211806 RepID=A0A2N0HJX2_9SPHN ---SLEATVAALANAGQGRIGVAATDLGTGRTV-SVLGSQPFPMASTSKLAIVATFLQGVD -QGRFSLSDRYPLMVPVPSASSTVAPVRAGATMTAWQLIDRTIINSDNQATDALLRVVGGP -AAVNKWVREAGLTGFSLNRDIATLVRARVVDQRDAATPLTMVQLLTGLHQGRWLSQSSTG -VILSAMERCVTGKRRLKALLPGEARVLHKTGTLSN-TSSDVGIIKTPDGRDIAVAIYVTG -QGG-KSFRDSRIASIARAIYDGy ->[subseq from] Class A beta-lactamase n=1 Tax=Blastomonas sp. TaxID=1909299 RepID=A0A2D6H2E6_9SPHN ---GLRDELQELWRTFPGKTGIAVRRIDGDWVI-GQRGGELFPQQSVSKLWVTMTVLEKVD -RGEVSLDQEVTITANDLTLHQPLAARVSREGETVRSLINEALTASDNSANDALLRTAGGP -GAVQDFLRRKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR -LMLETLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPARMQLMQAVSRAV---- ->[subseq from] Serine hydrolase n=1 Tax=Tychonema bourrellyi FEM_GT703 TaxID=2040638 RepID=A0A2G4EZV0_9CYAN ---ALKTQVQALATENTLTAGIFLVDLDSGSYL-NFNGDTTFASASTIKVPILVAFFQAVD -DGKVRLDQTLTLRAEDIVGGSGEMQDAPGKKYSALEIARKMIVVSDNTATNMMIDLLGGA -EVLNQHFATWGLRATVLNNKLPDLEGT------NTTSPKDLINIIAQIDRGNLVSVKSRD -RIFQIMQQTKN-DSLLPKGLGAEAIIAHKTGNINT-LLADAGMVDLPNGKRYLVAVMVKH -PPETEKPAQSLIRDISRMSYRY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. GY_G TaxID=2292257 RepID=A0A371B2E9_9SPHN ---QLEAELHEIWRAFPGKTGIAVQRIDGQWVT-GKRLGEWFPQQSVSKMWVAMTILDQVD -SGRLRLDQTVRIGMNDLAVHQPIRERVVANGESISSLLEQAITASDNTANDSLLRTAGGP -AAVRNFIERKQLGKIRFGPGERLLQSAYLADPIDGAAPDAIAGALSRLARGELLSPASTR -LLLAMMERTKSGPNRLKSGVPAGWRFGHKTGTGQSTGYNDIGIMTAPDGTRYAVVVMISS -TTAPVPDRMAMMQAVSRTVAAH- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Microcoleaceae TaxID=2053578 RepID=A0A355CDE5_9CYAN -----KPQIEQAIEQYSLSAGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFYQDVD -AGKVSLNETLVMKSDLVASGSGTMQDEADGTFSIRETVDKMITISDNTATNMIIERLGGI -AKLNERFRSWGLTDTIIRNWLGDFQGT------NTTSSVDMVQLLAMLSRDKLVSESSRE -QVLELLRHTTT-RTLLPSGLGAGAVIADKTGDIGF-VVGDAGIIDMPNGKRYLAAIFVKR -PYND-PIVRDFVRRISRIVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc punctiforme NIES-2108 TaxID=1356359 RepID=A0A367S0K8_NOSPU ---SLKNAVQNLAATNNLTPGIFLVDLDTGNYV-DINGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDDMLTMQQDMVAGGSGDLQKPPGTQYAALEVVTKMITISDNTATNMLIARLGGI -DALNQRFRSWGLTATTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -FMLDILRRTQR-DTLLPSGLGTGAKAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PAN-DPRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase class A n=1 Tax=Erythrobacter nanhaisediminis TaxID=604088 RepID=A0A1I5MTX6_9SPHN ---MLEARLQQIGEGFAGEVGIAAVEVTSGATM-AYNGDRPFPQQSVSKLWVSLTALDLVD -EGALDLSEPVAIRRGDLTVYQPIRDIVRTRGTDYRDLMERALTQSDNTANDRLLRRVGGT -QAVEAFMRRKGIEGVQFGTDERSKQSDYLDDPIDGASASGMAQALARLARGELLSSRSTE -FILSTLENTKSGPRRLKGGVPSGWSIAHKTGTGQHSGYNDVGVLTAPDGTQYSLAVMIAR -TRTSYAARFEMMQSVTRSVVEY- ->[subseq from] Serine hydrolase n=1 Tax=Calothrix elsteri CCALA 953 TaxID=987040 RepID=A0A2A2TAB0_9CYAN ---TLRTSIQSITAANSLTPGVFIADLDNGSYV-DFNGGAMFSAASTIKIPIIVAFFQDVD -AGKIRLDETITSTKSAIATGSGDIQYKPAGTYTALEVVTKMITISDNTATNMLIERLGGI -ETLNQRFRSWGLNTTTIRNILPDIEGT------NTTSPKELANLIAVMTKGNLVSMQSRD -RILDIMRRTVK-DNLLPSGLGQGATIAHKTGEIG-AILADAGLVDLPTGKRYIAAVIVQR -PRND-AGAEKLISSISRAAYQQf ->[subseq from] Class A beta-lactamase n=1 Tax=Dysgonomonas sp. 37-18 TaxID=1895907 RepID=A0A1M3LBR2_9BACT ----LRNKIQKIIQGKDATVGVALI-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN -KNNLTLDHQLYVKKGDLLPHSPLRDDYPQGELSVADIIRYTVSKSDNNGCDILFRLVGGT -AVVDRYIRGLGLSEFAITATEEEMHGPWEVQYTNWSTPYTAAQALEIFRTQDILPQPFHD -FLWDTLAGTTTGGNKIKALFPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD -SMESNDVNCGIIAQISKAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Chroogloeocystis siderophila 5.2 s.c.1 TaxID=247279 RepID=A0A1U7HP50_9CHRO ---SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASMIKVPVLVAFFQDVD -AGKIRLDERLTLKKELVGGGSGDMQKPLGTKFTALETATKMITISDNTATNLLIERMGGA -AALNERFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAQLMALIDDGKLMSLRSRD -RLLDIMRGTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPSGKRYIAVAMVKR -PHND-GRAQELIRQISRAAYQE- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UPL3_9BACI ----WQQAVENVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTMMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIAITALSR -GVTDKESAELTIARVAKAIYE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000E4F4A28 --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQGMDDCYKNWTTPIEAANLLELFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1WEK3_ECOLX ------------------------------------------------------------- --------------------------------MSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=A0A147HWJ0_9SPHN ---ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP -QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0008532722 ----WQQAVENVLKEAPGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLTHNCWELLNSMPTPDNNVATPAELNRLLIMIARKEILTESSCE -QMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Phormidium ambiguum IAM M-71 TaxID=454136 RepID=A0A1U7I3U8_9CYAN ----------------LFTPGVFAIDLETGNYA-EINGNNSIAAASTIKMPILIAFLQDVE -AGKIKWDEKLILKSEFRASGSGILRNKVGSEFTAGDVATRMITISDNTATNMVIDRLGGI -EALNRRFQEWGLSATKLQNPLPDVKGT------NTSSPKELAVLMARVMRGELLSAASRD -RMIEIMHQTEN-DNLLPKGIGEGAKIAHKTGNIGS-MLADVGIVNLPSGKRYVIAVMVQR -PRRD-VRAQKIIQQISNTTYQYf ->[subseq from] serine hydrolase n=1 Tax=Phormidium ambiguum TaxID=71191 RepID=UPI0009FEB9AE ----------------LFTPGVFAIDLETGNYA-EINGNNSIAAASTIKMPILIAFLQDVE -AGKIKWDEKLILKSEFRASGSGILRNKVGSEFTAGDVATRMITISDNTATNMVIDRLGGI -EALNRRFQEWGLSATKLQNPLPDVKGT------NTSSPKELAVLMARVMRGELLSAASRD -RMIEIMHQTEN-DNLLPKGIGEGAKIAHKTGNIGS-MLADVGIVNLPSGKRYVIAVMVQR -PRRD-VRAQKIIQQISNTTYQYf ->[subseq from] Beta-lactamase family protein n=1 Tax=Sphingobium sp. RAC03 TaxID=1843368 RepID=A0A1B3MS96_9SPHN ---RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID -AGQLALTDIVPRDVATMG---------PGAPLPVAQLLDLMLTQSDNHATDMLVARAGGP -AAVNAWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGRALSPASTH -AFITIMERCRTGKARLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ -DHRGRVMRDRIMAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium CG12_big_fil_rev_8_21_14_0_65_65_10 TaxID=1974094 RepID=A0A2M7HH52_9SPHN ---ALDRRLNEIGSKFAGQVGIAVRPVESDRTM-HYRGLEPFPQQSVTKTWVALAAFRQVD -EGKLALDEPRIVRREDLTLHQPIRAEVLRKGTDYADLLDRALTRSDNTANDVILRRVGGP -DAVQGTLDKLGLGSIRFGTDERTKQSGYLADPIDGAPPVAVVAALARLAKGELLSDDSTE -RFLKILSETRSGPNRLKGGLPPGWTIAHKTGTGQQTGYNDIGLITAPDGRRYAVAVMIAR -TEQRVPERMEMMHEVVAAVVEY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235J5T9_9NOSO ---SLKNAVQNLATTNNLTPGVFLVDLDTGNYV-DVNSSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDSIAGGSGNLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGI -EALNQRFRSWGLTTTTIRNQLPDLQGT------NTTSPKELGNLMAIVSQGNLVSVPSRD -LMLDILRRTEK-NTLLPSGLGTGARAYHKTGDIGT-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYEEf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf34 TaxID=1736216 RepID=UPI0009EBCA19 ------------------------------------------------------------- ----------------------------------AAKVMALMIIRSDNQATDQLLAALGGP -VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA -LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter buctensis TaxID=1503981 RepID=UPI0013681E46 ------------------------------------------------------------- --------------------------------LPASELIDLAITRSSNPATDALLAAVGGV -SAVNAWARRAGIEEFNLTRDIATLVRATQIDLRDSSTPEAMVELVAGIYQGRWLRPESRA -VIVRAMENCRTGTRRIPALLPAGALVAHKTGSLNN-TSSDIGIITAPDGRSIAVAIYVTG -QG-TRANREARIASIARAIYDGy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sanguinis TaxID=33051 RepID=UPI0009EF0003 ---ELVSAINRLSANFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTFVGGP -QAVRAMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=bacterium A52C2 TaxID=1855383 RepID=A0A1H9LLM6_9BACT ---DLQAQLDALAHKAPGKFGISVLDLESGKRW-GVDAGSAYPMMSVFKAPLGATVLAQAD -AGKISLSQHVTIRRADLRTASRIAEEFRGEQFTVQELLVDAVSYSDNTAADALVRLIGGP -QVITSFLEGHGIRGLHVDIDEGGVSHAYLSDPRNRSTPDAAVAFLQTLWNGRLLPTKSTK -HLLDLLYGQTK-PSRLRAGIPAGVRLADKCGTSETAAFNDIGIMTWPDGRTVIVAAFLTG -SKASQAERNQLFADLAH------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides dorei TaxID=357276 RepID=UPI000E48E12E ----LKTEIRHIIKDKKATIGVALI-LDGEDTL-AVNNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKRYFKPYSPLRDKYPQGNLPISELLAYTMQLSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITTTEDEMHQDMDDCYKNRTTPMEAANLLELFMTQDSMKNEYTN -FLKHIMIECETGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGNRYVVAVFVKD -SKENMETNTKIISDISAAIYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A224A9A8_SHIFL ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Gloeocapsa sp. PCC 7428 TaxID=1173026 RepID=UPI0012DC1CDB ---SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASMIKVPVLVAFFQDVD -AGKIRLDERLTLKKELVGGGSGDMQKPLGTKFTALETATKMITISDNTATNLLIERMGGA -AALNERFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAHLMALVDDGKLMSLRSRD -RLLDIMRRTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPSGKRYIAVAMVKR -PHND-GRAQELIRQISRAAYQE- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SX32_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPCSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas solaris TaxID=2529389 RepID=A0A558RD29_9SPHN ----LLSELERLGRGFDGVVGIAVRDVQAGWSV-SWNGTGRFPQQSVSKLWVALTLLDAVD -RGTLRLEDPITVRRSDLTLHQPVRAMMGPDGTSIRNLLTIAMTQSDNTANDVLLQRVGGP -SAVRAFFTRASISGIAFGPGEKLLQSRYLADPMDGAQPEGMVAALARLRKGDILSPGSTQ -VLLSIMAQSKTGPQRLKGGLGENWAFAHKTGTGQATGYNDVGLLTAPDGRTFAVAVMIAS -TRQPIWARMQLMQNVTRAVV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649V1Q5_ECOLX ------------------------------------------------------------- --------------------------------MSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFPLDRTEPTLNTAIPGDPRDTTSPRAMAQSLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVEGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDV------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=A0A1I5GEN1_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -FAIQQWLSSHKIAGIRMDRTIAQLLRGHLADIKDVATPVAMVTLLEKLDNGTVLTAQSRA -FLFELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BQ58_BREBE ----WQQAVENVLKEAPGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLTHNCWELLNSLPTLDNNVATPAELNRLLIMIARKEILTESSCE -QMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] serine hydrolase n=1 Tax=Blastomonas sp. CCH5-A3 TaxID=1768761 RepID=UPI000826829E ---GLRDELQELWRTFPGKTGIAVRRIDGDWVI-GQRGGELFPQQSVSKLWVTMTVLEKVD -RGEVSLDQEVTITANDLTLHQPLAARVSREGETVRSLINEALTASDNSANDALLRTAGGP -GAVQDFLRHKGLANIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR -LMLETLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPARMQLMQAVSRAV---- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A415BNG6_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLELFMTQDPMKNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNTKIISDISTAVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. AF39-11AC TaxID=2291999 RepID=A0A415II51_9BACE --qKIEQQIDSVLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KDHVGLDSLIEVKSSQLTPYSPLRDKFPDQDISLGELLKYTISKSDNNTCDILIEYAGGI -DQVNEYVKSLGIKDCNLAATETLMHTS-EDAYLNWSTPEEVVRLLNIADKHPLFAAQYKD -FLQAIMQETSTGKDKLKGQLPANVIVGHKTGSSDRTADNDAGFVILPDGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Class A beta-lactamase n=1 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=A0A2L2NZA1_9NOSO ---SLKNAVQNLAATNSLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGM -EALNQRFRTWGLTTTTIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQK-DTLLPSGLGTGARAFHKTGDIGM-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYQEf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. Root214 TaxID=1736491 RepID=A0A0Q8S6I7_9SPHN ----LNDRIYELWRAFPGKTGIAVQRIDGEWSL-SQRGGELFPQQSVSKLWVTLTVLDAVD -QGRMTMDQRVRIGPEDLVVHQPLAARVRAERMSVRDLIETAITHSDNLANDSLLRTVGGP -AAVRAFIAKKDLGSIRFGPGERLLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQGVMSRTRSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS -TTSGIPARMALMQSVSSAVAEY- ->[subseq from] Serine hydrolase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1B7X2P4_APHFL -----KNSLQTLTTASDLTPGVFLLDLDNGGYV-DINGNASFPAASTIKIPILMAFFQDVD -AGKIRLDEILTLEKEMIVGGSGVQYQTPGSKYTALDLATKMITISDNTATNMLVAKLGGQ -EALNGRFRGWGLTTTMIRNPLPDLGGT------NTTSPRELGNLISMVNQGNVVSMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADVGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] Beta-lactamase BlaZm n=2 Tax=Macrococcus canis TaxID=1855823 RepID=A0A4P9CIP0_9STAP ---KIKEDIKVIENKYNIQAGVYVNDLTDKQKL-SYNEELLFPYASTFKVINSALLIEKLG ---MNNLDKEVKVSERDIVLYSPIIEKYKNKNVSLKMLIEAALLYSDNTANNLIIEELGGL -KEVEKRLSALGIKGVNVNRKEVALNFYDPKKNEDTISAKNMSKVLIKMLTGDVLEYKEQI -FLIDLMKKNKTGTTLIKKGMDKKFIVGDKSAQGNYGVRNDIAVVYKKQSKPIIVVVFTKA -KNEKQQPSDTPIVEISKVI---- ->[subseq from] Beta-lactamase n=1 Tax=Sphaerospermopsis reniformis TaxID=531300 RepID=A0A480A1C1_9CYAN ---TLKSTLQNLATANSLTPGVFMVDLDTGGYV-DINASTSFPAASTIKIPILVAFFQDVD -GGKIRLDEMLTMEKEMVAGGSGNLRTPVGSKYTALDVATKMMTISDNTATNMLITRLGGQ -EVLNGRFRSWGLTTTAIRNILPDLEGT------NTTSPKELADLIAKVNQGNLVSMRSRD -LMLDIMRRTER-NTLIPSGLGEGARAYHKTGDIGT-MLGDAGLIDIPTGKRYIAAVMVKR -PHND-PAAETLISSISQAAYENf ->[subseq from] serine hydrolase n=1 Tax=Sphingorhabdus sp. IMCC1753 TaxID=2509719 RepID=UPI0013177A7F ----LENLLHEQWRQFPGKTGVAVMRIDGGDWVlGRRLDELFPQQSVSKTWVAMTILDLVD -QGKLKLDQRVRITTDDLAVHQPIRERVIANGETVLSLLEQAITASDNTANDSLLRTAGGP -QAVRAFMTRKKLSAIRFGPGERALQSRYLANPVDGASPEAIVRALGKLAKGELLSATSTR -LLLDIMSRTSSGPNRLKAGVPAGWRFLHKTGTGQSTGYNDIGIMTAPDGTRYAVAVMMGS -TTSSIPERMAFMQFVSRSVATY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 28-63-12 TaxID=1970434 RepID=A0A258RUJ9_9SPHN -----VAAVNALRAEFDGTVGIAVRSVDKGWSV-STNGDLKLPQQSVSKLWVAMTVLDTRD -AGRLTLDDPVTITREDLTLHQPIAAMVTGDGATVGELLQRALTTSDNTANDRLLRYVGGP -EAVRAFIKRKGLGAINFGPGERVLQSSYVTNPPDGAAPAAIAGALAMLKKGELLSAQSTN -YLISTMESSRTGKQRLRGAVPSGWRFGHKTGTGQTAGYNDVGILTAPDGESYTLAVMIGD -TPRPIPERQALMQAVVSSVIAY- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=UPI000CF30942 ---SLKNAVQNLAATNSLTPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILIAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNLQYKPAGTYAALEVVTKMITISDNTATNMLIAKLGGM -EALNQRFRTWGLTTTTIRNQLPDLEGT------NTTSPKELGNLMAIVSQGNLVSMPSRD -LMLDILRRTQK-DTLLPSGLGTGARAFHKTGDIGM-MLADTGLIVVPTGKRYIASVMVQR -PEN-DPRAEKLISSISRAAYQEf ->[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides plebeius (strain DSM 17135 / JCM 12973 / M2) TaxID=484018 RepID=B5D1X3_BACPM --qKLYANIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGDYCK -RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTRTLFDKPHQE -FIKESLITCQTGTNRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQLPNGHRYTLVIFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sanguineus TaxID=198312 RepID=A0A1M7SFL7_9SPHN ---SFQQRIAELAEPSRGRIGVAAVDLATGEEI-MVLGDQLFPMASTSKIAVAAAYLEMVE -KERFSLTSEFPLLLPIRSAFSSARAPVRKGQMPAIDLIEIMITRSSNPATDALLAAVGGP -DIVNEWVRRQGIADFSINRDIATLVRATHIDSRDAATPRAMARLLAGLYRGDFLSDESRR -VLLGAMSRTVTGKRRIVAHIPAEARVSHKTGSLNN-TSSDIGLIECPDGRTIAVAIYVTG -QG-TRLAREERIAAIARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis bauzanensis TaxID=651663 RepID=A0A246JPI1_9SPHN ----LSERIHFLWRAFPGKTGIAVQRIDGEWAL-AERGGDLFPQQSVSKFWVALTALDAVD -QGRLRLDQQVRIGPEDLTLYQPLAARVRAQGMTVRSLIETAITQSDNTANDSLLRTIGGP -GAVRAYLSKKDLGAIRFGPGERLLQSNYLANPIDGASPTAIASALARLARGTLLSPESTE -YLLDVMSRTKSGPRRLKAGLPPGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGT -TTSPIPARMALMQAVSSAVAE-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A2T7VP17_9SPHN ---RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -QAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFTETSTR -ILLDTMGASVTGRARLRAAVPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQSVAAAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Gloeocapsa sp. PCC 7428 TaxID=1173026 RepID=K9XKN1_9CHRO ---SLKTTVEQLAAQKNLLPGVFFLDLDTGAYL-EINGNSTFASASMIKVPVLVAFFQDVD -AGKIRLDERLTLKKELVGGGSGDMQKPLGTKFTALETATKMITISDNTATNLLIERMGGA -AALNERFLSWGLPATQIRNLLPDLEGT------NTTSPRDLAHLMALVDDGKLMSLRSRD -RLLDIMRRTVT-NTLLPRGLGEGARIAHKTGDIGS-LVGDVGLVDMPSGKRYIAVAMVKR -PHND-GRAQELIRQISRAAYQE- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf257 TaxID=1736309 RepID=A0A0Q4U1C5_9SPHN ------STINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP -QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFTIAVMIGD -TTEDIRKRQQLIQNVAAAVAN-- ->[subseq from] Beta-lactamase n=1 Tax=Oxalobacter formigenes HOxBLS TaxID=556268 RepID=C3X3G5_OXAFO --qSLQEKIGALVAGHRAHIGVTVGNAGGTERA-AIAADALFPMQSVYKFPIALSVLDRVD -RGELSLEKRIAISRSELRPWSPLRDRYRKGKIPLAEIVRTTMTDSDNNGCDILLRLAGAP -EKVTAFLRRHGVAGMTVATTERAMHGDWPIPFRNSSTPAAATRLLRLFEEKKLLKPRTHA -FLWNAMKNSGLSPERLRSSLPPQTPLIHKTGTSTQGTINDMGIIVLPDGQPVFVTVFVSH -GKEPKAVTEKMIPDIARVTWRHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. C-1 TaxID=262667 RepID=A0A0M8JDX2_9SPHN ----LQDRIFELWKAFPGKTGIAVQRIDGEWAL-AQRGGDLFPQQSVSKLWVTLTVLDAVD -QGRIKMDQRVRIGPEDLVVHQPLAARVRAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -SAVRSFIAKKDLGSIRFGPGERMLQANYLANPVDGASPAAIASALTRLARGTLLSPESTE -YLQGVMSRTKSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS -TTAGIPARMALMQSVSSAVAEY- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. Root655 TaxID=1736578 RepID=A0A0Q8FJG7_9CAUL --eKLTVQLQQVADRAPGTLGVAIEDLSTSQII-SFNGERRFPLQGASKAPLGAAVLAEVD -ARRLKLDQVLTIEDVDLSPHSPIADVWPGRKYTVAELLERAVGDGDNTAADVLMEAVGGP -GAVTAWLQGRKVKPVDIDRYERQLQPAYLADPKDTATPLGAVRFLEALNQGELLSPASTR -RLVKVMIASPSAPGRLRAALPDGARLAHRSGTARTPAVNDIGVYRLKDGRKFAVAVFLSG -SSLNEADQDRVIADVGRIVIK-- ->[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=2 Tax=Isosphaera pallida TaxID=128 RepID=E8R687_ISOPI ----LERRLRPLIAAHKGDVGVMVKHLGTGETF-AHRADAPMPTASLIKFPLLIEAYRRVA -TGALDLKTPVTLHDEDKVPGAGILTYHFSQGIPLRDVLRLMIVYSDNTATNLALDAV-GL -DAVNAEMARLGLKRTKFHSKVYRRDTSIDPEGSGVTTAAEMITLWERLHLKKLAEEALCD -AMLDHLLHCDD-KSMLVKELPPGTKVAQKTGAVSD-VRTAAGILYTPSG-PIAVCVLTAR -NQTPDNAAERFSARLAREVYDHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium GWF1_63_6 TaxID=1802168 RepID=A0A1G3JC16_9SPHN ---RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID -AGQLALTDIVSRDVATMG---------PGAPLPVAQLLDLMLTRSDNNATDMLVARAGGP -SAVNAWVAALGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLIAAIRTGKALSPASTH -AFITIMERCRTGKARLSGMLPPGTTIAHKTGTIN-GTGNDTGVVTLPDGRMFAITVFVMQ -DHRGRVMRDRIMAEAARAAYDYf ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=A0A1T3FE39_9FLAO ---ELLEKINTITKGKKATVAVSVLGIENDFQFsNAYGNLKMPMMSVFKFHIALAVLNQVD -RGNLALDQKILVKKSDLLEWSPIREKYPDGNLPLSEIITYIVAQSDNNGCDILLRLIGGV -KTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGMFLSKRSTA -FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD -SMESEEVNCGMIAQISKVVWDA- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 2SG TaxID=2502201 RepID=UPI0010F9AFDA ---QLTSAIDALARNFDGKFGIAIRAVDAGWTVtSPGARTRLPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -AAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFTETSTR -ILLDTMGASVTGRARLRAALPAGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQSVAAAVANY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis sp. LPB0140 TaxID=1913578 RepID=A0A1L3JAM6_9SPHN ------RAIAGLEAEYGGRLGVALWDASGGGYIgGHRSEERFALCSTFKLLLAAFILRQCD -IGKLSLDKKISYSQSDILSHAPETQKYISRGMTVEQLAKAAQISSDNVAANLLLPLIGGP -KGFTKLLRFFGDDVTRLDRIEPMLNFVPMGETRDTTSPSAISSTIAQIFTAGLLTDASAA -TLRQWTMATNTGPNRLRKYLDADWVAGNKTGTAYNGKFNDIALLWDKHRLHYIITAYYEA -PIPKDPKHEEILAQIGKIT---- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides nordii CL02T12C05 TaxID=997884 RepID=I9S0R3_9BACE ----LTKELDILLQGKQAKVGVAVV-FEGRETF-TYNNPHHYPLMSVFKFHQALAVMDYLD -TRQLPLETEIYVRKADLLPYSPLRDARPEGEISVGELLRYSISESDNNACDILLRYIGGT -GVVDKYVRTLGIEDFKIEANEEKLNEAFEYQYLNWTTPFAAVQVMEKFRTETLFRHSYKE -YLEKLMIGTVTGNDKLKAGLPREVVFGHKTGSSGRNGDNDMGFVRLPDGRQYSIAVFVTD -SREDDKTNATLISEISRKVYEYy ->[subseq from] Class A beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A1Q6G355_9BACE ----LTKELDILLQGKQAKVGVAVV-FEGRETF-TYNNPHHYPLMSVFKFHQALAVMDYLD -TRQLPLETEIYVRKADLLPYSPLRDARPEGEISVGELLRYSISESDNNACDILLRYIGGT -GVVDKYVRTLGIEDFKIEANEEKLNEAFEYQYLNWTTPFAAVQVMEKFRTETLFRHSYKE -YLEKLMIGTVTGNDKLKAGLPREVVFGHKTGSSGRNGDNDMGFVRLPDGRQYSIAVFVTD -SREDDKTNATLISEISRKVYEYy ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. HPS0048 TaxID=1078089 RepID=U6RA83_9BACE ----LTKELDILLQGKQAKVGVAVV-FEGRETF-TYNNPHHYPLMSVFKFHQALAVMDYLD -TRQLPLETEIYVRKADLLPYSPLRDARPEGEISVGELLRYSISESDNNACDILLRYIGGT -GVVDKYVRTLGIEDFKIEANEEKLNEAFEYQYLNWTTPFAAVQVMEKFRTETLFRHSYKE -YLEKLMIGTVTGNDKLKAGLPREVVFGHKTGSSGRNGDNDMGFVRLPDGRQYSIAVFVTD -SREDDKTNATLISEISRKVYEYy ->[subseq from] hypothetical protein n=1 Tax=Granulicella sp. L60 TaxID=1641866 RepID=UPI00131A8392 ----LQRRVQHLAAGFPGKVGILVRNIETGAQV-GINADDEFPMASTYKVAIMTQVFRDVE -AGRLSLTERVPLTENELRPGSGLLRYMTPGLPTIHDLVLMMITVSDNEATDLLLKRVGGG -ARVTATLQQLGIPNIRVDRPTLEIIGTLTDDPRDHASPRAMGDLLMKIFKSEVVSEKSSQ -DMLAIMQNQQL-KTRIPRYLE-DVAIASKSGTIGD-VTNDVGILYAGNQ-HIVISVYTLK -ANVQTEQAEEFIARTARETYDYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1Y0BAT1_9BACT ------------------------------------------------------------- ----------------------------------AQQLMERMLIHSDNAATDILIRNLGGP -QAIQGWVSWHGFSNMRVDRTIAQLLRSPRWDSRDSATPMAMVQLLQRIDSGKVLKPGSKA -YLLSTMSRCMTGKNRMRALLPAGTRVEHKTGTLS-GLTSDVGFITLPDGRRIAVALFARG -GS----DRPNTIAQAARAIYDGf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. HDW5B TaxID=2714927 RepID=UPI001407839D --nTLRQEIQDIIQNKKATVGVAII-FDGTDTL-TVNNQYRYPTMSVYKFHQALAVLDYLD -KHNLPLEQQVYVSKSALHPYSPLRDKKPEGNMPVKELMQYSVSQSDNNTCDILFNFLGGT -TPVEQYIKGLGIQQIAITKTEKEMSEDFDNQYGNWTTPYAAVQLLEIFLQQELFASHYKN -FLLDALIQTSTGKDKIKGLLPAGTVVGHKTGMSSKAGDNDLGFIKLPNDKNLSIAVFIVN -SIENDTTNAEIIAQISKVTYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR485 TaxID=1500294 RepID=UPI00064627AF ---DLKKTIESIISNKKADVGVSIIGPDQKETI-QINGNTLYPMLSTVKFPIALTVLKKVE -KGELSLQQKLFIKKEELLEWSPFKKEHPEGNISLEEALKWIVSYSDNNISDILMRLVGGP -EPVQQLVNS---NDCIIQNNEEGMHKDWESQFVNKITPNEAIRLLTAFSNGKILNKEHSL -WLYNIMLNNTAGPKRLKGNLPPQVKVAHRTGTSFTGAINDFGIIELSDNKKIYIAVFVHD -TYEKFENAEAIIADISKATYDYy ->[subseq from] Beta-lactamase class A n=2 Tax=Rubidibacter TaxID=582491 RepID=U5D5N7_9CHRO ---SLQNQFSELAAQSGLEPGAFFYDLDTGEYV-NFNGDRAFSAASTIKVPVLVAFFQALD -RGEVQLDELLTMTPDLIGGGSGAMQYAPGTQFTALETATQTIVISDNTATNMLIHRLGGA -DVLNAQFQDWGLTETAIRNPLPDLDGT------NTTSPQDMVRLLARVERGELLSLRSRD -RLFAIMERTKT-KTLLPRGLGPGATIAHKTGDIGS-SVGDVGAIDLPTGKRYLAAVLVAR -PHND-SRAQELIRNFSRRAYEHf ->[subseq from] Serine hydrolase n=1 Tax=Paenibacillus sp. N3.4 TaxID=2603222 RepID=A0A5C8MES1_9BACL ---NLQQKLENAVKDERGTFGVAVKHLGTKEEA-NINEGRLFQMASSFKVPILTTLYRDVE -AGKIRLDERVKLKWEERVPGSGVLQQLDPEAVSVKDMATLMIIVSDNYATDRVLDLVGGP -KQVEAYMKEQGLNHILVKQSCWDLLTDLTSTEHNVASPRDMGKLLEMIAQKEMLSESSSN -GVLDIMLKQQF-RNRIPYLLPEQVKVAHKTGSIGS-VVNDVGIVYLPEEKGIFTIAVFSQ -GNSFRREGEQAIARLAKAAYDHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 35-24ZXX TaxID=1545915 RepID=UPI00053C0799 ---GLRDELAALWRGFPGKTGIAVRRIDGDWVV-GQRGGEPFPQQSVSKLWVTMAVLEKVD -RGELSLDTPVTITHDDLTLHQPLASRVAREGETVQTLINDALTASDNSANDALLRTAGGP -GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQASTR -LMLDTLGRTRSGPNRLKAGVPVGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLAE -TTASIPQRMQLMQAVSRAV---- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. YGSMI21 TaxID=2077182 RepID=A0A2D3RE71_9SPHN ---ALVREIDQLWRTFPGKTGIAIKRIDGEWEF-GHRIDEYFPQQSVSKLWVAMAMLDKID -QGRASLSDPIRIGKEDLTLHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP -EAVRKFIDKNDLGKIRFGPGERLLQAAYLADPVDGASPRAIVRALDKLARGELLSPNSTK -LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMLGD -TTASIPERMRMMQAVTRAVGR-- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. HK-01 TaxID=196308 RepID=A0A2Z6CXD9_9NOSO ---SLKNNFQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNFQFKPAGTYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTVIKNQLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD -IMLDIMRRTER-DNLLPSGLGSGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR -PNND-PRAEKFISSISRTAYE-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A348UZK5_9BACT ---RLTGQLAAIKDSLDGILGLAIKDLVTGKTI-FINENEIFPQASSIKIAILMEVLKQAE -ENRLRLEDFVDLKPENKVGGGPILNFLGNPSLSVHDLCVLMIVLSDNTATNLLIDLV-GM -EAVNRRLQVLGLNQTRLRRKMMDLKAA-EEGRENISTPREMLSLLEKIWQGKVLGAEQRQ -LFFDFLSLPKE--SPLQQAVPDGVTVADKPGELE-AVRCDSGLVFLRKR-PYIICVMTTY -LG-PREDGNAIIRKIGRLVYEHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E2ZXB8_SPHSX -----LSTITALESQFDGIVGIAVTSVDEGWSV-AANGERRMPQQSVSKLWVAMTVLDYRD -QGRLTLDDPYTVTKADLTVHQPVATLIGENGTTIRELLRRALTNSDNTCNDILLRYVGGP -DSVRDFIARKQLGAIRFGPGERLLQANYIADPPDGATATAIAQALARLKRGELLSADSTS -WLIATMESSHTGRQRLRGAVPAGWSFGHKTGTGQTAGYNDVGILTAPNGKSYTIAVLIGD -TSRTIPQRQELMQAVVASVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=A0A367PV38_9NOSO ----LKNAVQNLAANYNLAPGVFLVDLDTGNYV-DVNGSTSFPAASTIKVPILLAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGDMGSKPAGTYNALEVVTKMITISDNTATNMLIARLGGM -EALNQRFRTWGLTTTTIRNILPDLQGT------NTTSPKELSNLMAIVSQGNLVSMPSRD -LMLDILRRTQR-DTLLPSGLGTGARAFHKTGDIGT-MLADTGLIVVPTGKRYIATVMVQR -PEN-DPRAEKLISSISRAAYQEf ->[subseq from] Beta-lactamase n=1 Tax=Methylibium sp. T29 TaxID=1430884 RepID=W7W894_9BURK ------------------------------------------------------------- -------------------PWSPVTEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP -QALTQYARQLGDKITRLDRNEPDLNTRVEGGSLDTTSPRAMAMTMNKLLLGDALSPLSRN -LLRQWLLENTTGGKRLKAGTPADWTVGDKTGTNKT-DANDIGILLPPQGAPVLVTAYLAD -STASSQIKDATLAEVGRL----- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. AX6 TaxID=2653171 RepID=A0A653YVE1_9SPHN ------SNIERMHSDFGGRVGIAIRSIDDGWTV-SANGDQPMPQQSVSKMWVAMTILDQRD -RGRIDLSDSVTITRQDLTLHQPIASLVVRNGTTVENLLRRAITSSDNTANDRLLTLAGGP -SAVNEFIRRKSLGSIKFGPGERLLQAAYVANPPDGASAHAMVDALARLKEGNLLSAASTT -WLVSTMQNTRTGRSRVKAGTPSGWLWGHKTGTGQTAGFNDVGIMTAPDGKSYAVAVLIGE -TSRSVPQRQDLMQRVAATVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium cloacae TaxID=120107 RepID=A0A1E1F2E1_9SPHN ---RLLAQFESLAALSDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILAMAD -AGALSLQDQVPLDPA-----------QPARLRSLHDLIDLMLTHSDNDATDALVARAGGP -ATIHQWVAALGVKGLRVDSDTAHLLYAFTLDPRDTSTPRAMNALLAAIQLGQALKPASTV -YLLEMMERCHTGKARLKAMLPPGARIAHKTGSLN-GYGGDVGIVTLPDGRMFAVSVFVMK -DYKGRATRDSIMAHAARAAYDYf ->[subseq from] Penicillin-binding protein n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1R0T8_9CYAN ----LKSAIQSLAASTNLTPGVFLVDLDNGSYV-DLNGAASFASASTIKIPILVAFFQDVD -AQKIRLDESLTMEKEVVAGGSGNMQKPVGTQFTALEVATKMMTISDNTATNMLIARLGGI -DALNQRFQSWGLTTTAIRNLLPDLGGT------NTTSPKELGTLMAMVGKGNLVSMRSRD -RILDIMRRTVR-NQLLPAGLGPGATIAHKTGNIGT-ILGDAGLVDVPSGKRYVVAVMVQR -PRND-PGAEKLIVSISRVAYEQ- ->[subseq from] Serine hydrolase n=1 Tax=Porphyrobacter sp. YT40 TaxID=2547601 RepID=A0A4Y6VY83_9SPHN ----FEQRIRELADPAQGRIGVAAIDLATGEEI-MVLGDQLFPMASTSKVAVAATYMSMVE -QGRFSLTSEFPLMLPVRSASSPKAPVRAGQTMQAIDLIEIMITRSSNPATDALLAAVGGP -EVVNNWVRRQGINEFSINRDIATLVRVTHIDNRDAATPRAMVRLLAGLYRGEFLSDESRR -VILGAMSRTVTGKNRIPAYIPLEARVSHKTGSLFN-TSSDIGLIECPDGRVIAVAIYVTG -QG-TKLARQDRIAAIARALYDGf ->[subseq from] HGC-2 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0M2_9ZZZZ --qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TIENNRRYPLMSVFKLHQALAVGDYCK -RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLKKTLFDKPHQE -FIKEALVTCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D107AA4 ----WQQAVENVLKEASGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLTHNCWELLNSMPTLDNNVATPAELNRLLIMIARKEILTESSCE -QMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAEFTIARVAKAIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Blastomonas sp. AAP25 TaxID=1523416 RepID=A0A0N1LFD2_9SPHN ---GLRDELAQLWRSFPGKTGIAVRRIDGDWVV-GQRGGELFPQQSVSKLWVTMAVLEKVD -RGELSLDTEVTITPEDLTLHQPLAARVAREGESVRTLINEALTASDNSANDALLRTAGGP -GVVNDFLRRKGLSSIRFGPGERLLQSAYVADPIDGASPEGIVDALARLARGELLSQSSTR -LMLDTLGRTRSGPNRLKAGVPAGWQFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGE -TTAGIPARMQLMQAVSRAV---- ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter colymbi TaxID=1161202 RepID=UPI000A3942C3 ---TFEQRIAQLADPSLGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATFLEMVE -KGKYSLTSEFPLMLPVASASSAKAPVRPGQYLPAIDLIELMITRSSNPATDALLAAVGGP -AVVNDWIRRQGITNFSINRDIATLVRASYIDTRDAATPRTMARLLAGIYRGEYLSDSSRQ -VLLGSMSRTVTGKRRIPAHIPLEARVSHKTGSLSN-TSSDIGLIECPDGRVIAVAIYVTG -QG-TKQAREERIAAIARALYDGf ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR480 TaxID=1500296 RepID=UPI000647E2CF ---DLKKNIESIIANKKADVGVSIIGPYQKETI-QINGNKLYPMLSTVKFPIALTVLKKVE -KGELSLQQKLFIKKEELLEWSPFKKEHPEGNISLEEALRWIVSYSDNNISDILMRLVGGP -ELVQQLANS---KDCIIQNNEEDMHKDWESQFVNKITPNEAIRLLEAFNNRKILNKEHTL -WLYNTMLNNTAGPKRLKGNLPSSVKVAHRTGTSFTGAINDFGIIELSGKKKIYIAVFVHD -TYEKFENAEAIIAEISKAAYDHy ->[subseq from] Putative beta-lactamase n=2 Tax=Brevibacillus brevis TaxID=1393 RepID=C0ZJM2_BREBN ----WQQVVEDVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTMMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPSELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMVAITALSR -DVTDTEAAELTIARVAKAIYE-- ->[subseq from] Serine hydrolase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A175Y590_9SPHN ---RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -SAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFSETSTR -ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQAVAAAVAN-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7V4S3_9BACL ----WQQAVENVLNEAPGIFGIAAVHLETGETA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELVGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTTVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Dysgonomonas sp. TaxID=206096 RepID=A0A212JS98_9BACT ----LRNKIQKIIQGKDATVGVALI-VDGKDTL-TINNNFRYPTQSVYKFHLALAVLDYLN -KNNLTLDHQLYVKKGDLLPHSPLRDDYPQVELSVADIIRYTVSKSDNNGCDILFRLVGGT -AVVDRYIRGLGLSEFAIAATEEEMHGPWEVQYTNWSTPYTAAQALEIFRTHDILPQPFHD -FLWDALAGTTTGGNKIKALLPEGTFVAHKTGSSFRNAENDIAIIQLPDGRYYSLVVFVAD -SMESNDVNCGIIAQISKVVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Cylindrospermum stagnale PCC 7417 TaxID=56107 RepID=K9WQQ4_9NOST -----KTAVQNLAAANNLTPGVFLVDLDTGSYI-DVNGTTSFPAASTIKIPILIAFFQDVD -TGKIRLDEMLTMQQNMIAGGSGNLQYKPALTYSALEVATKMITISDNTATNMLIARLGGM -EALNERFRTWGLASTAIRNQLPDLPGT------NTTSPRELGNLMAMVNQGNFVSMRSRD -LMLDIMRRTER-DNLLPSGLGAGARTYHKTGDIGT-MLADVGLVDIPTGKRYIAAIMVRR -PNND-PRAEKLISSISRVTYQQ- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B0XRU8_9BACT -----GESLRRIARRVGDAVGVSALHVESGARI-SFNGDRPYPMASVSKVPMALEFLRRVD -LGQIDPSETVVVTVEEFRAHSPLADWSGARSVTVDSLFSLMLAQSDNTATDVILNMSGGP -EAATRHLRRLGVEGVRVDRSEARTFARYGTDPRDTATPDGMTDLLLTIHEGKGLSPESRA -WILDVLDRSRSGRGRMRGRLPPSTFVAHKTGTMG-GAINDVGIVILPDGGHLIVSVFVNT -LRRPTWRRERTIAEMTRLLYDYf ->[subseq from] Metallo-hydrolase family protein n=1 Tax=Sphingorhabdus wooponensis TaxID=940136 RepID=A0A3R8S411_9SPHN ------NLLDDQWRAFPGRTGVAIMRIDGGEWItGKRADELFPQQSVSKTWVALTILDLVD -QGKIRLDQKIRITRDDLAVHQPIRDRVIANGVTVLSLLEQAIIGSDNTANDSLLRTAGGP -QAVQNFLLRKKLGAIRFGPGERAMQSRYLADPIDGASPEAIVRALAKLAKGELLSPASTR -LILGIMSRTSSGPNRLKAGVPAGWQFVHKTGTGQATGYNDIGLMTAPDGTRYAVAVMMGS -TTASIPQRMAFMQFVSRTVATY- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X708_9BACT --kALEQKLTSICSRAQGSIGVTAVHVETGRAV-SVNGNAVLPLYSVFKLPLAITVLKDVE -ANRLKVEQMVHVTPDEIVPGTPENTALWAKPRTVAELIEFSISRSDNTSTDKLLQLVGGP -TRVTEQMRSLGFNNLDIHSTVMGYVKT--RQSVNTGSADDLANLLTQLQQGKILQPAQSQ -LLVGYMRGTITGMRRLRGDLPPGTVVADKTGSGERNTTNDVGLITLPNGGTIAMAVLVTD -SRLVDTAQEKIIAELARAAFDAy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=A0A0Q4L612_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMALMIIRSDNQATDQLLAALGGP -VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA -LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] class A beta-lactamase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFBAC40 --qNLKRDICQIISQNRAHVGISIKGFEKEDTI-NINANDTFPLMSVFKFHIALAVLQRVD -DGVLKLTQKVLVEKSQLHSWSPMRDQYPHGQLSLDEILRYTVSNSDNNGCDILLNLIGGA -KGLQKYIRSLGADDFTVSVNEFQMRS-WENSYLNYSTPMETTKLLEKFYNGLILKANSTD -YLYRLMVETTRGTRYMKSGLPQAAEIAHRPGLSGRIAMNDVGIVKLPNGQYFIISIFLKD -IMQDDRQAEEFFSEVARLTWEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Parasphingopyxis lamellibrachiae TaxID=680125 RepID=A0A3D9FFP4_9SPHN ---QLSDSVTALGSAFNGEVGIAVRDVEEGWTV-SWNGERFLPQQSVSKTWVAMTVLDQVD -RGEMSLDRMVRVRPEDAVVHQPMLSRMGNGGASIRELFTQAMTRSDNLANDRLLWLSGGP -EAVRAFFARNNLEGLRFGPGERELQSRYLADPVDGATANGMVEALARLVRGELLSERSTE -LMISTMRASRTGPQRLRGGVPSGWQFGHKTGTGQVAGYNDVGIVTTPDGRNYAVAVLIGN -TRVGIPARQRLMQAVMGQVVSH- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. S6-262 TaxID=1166340 RepID=A0A1H8HBQ2_9SPHN ----LQMAIQSLARGFQGRAGIAVRAVDEGWTV-EANGRQREPQQSVSKLWVAMTLLDLRD -QGKARLDEPIVVRPEDITLHQPIAYLALKGDTTVGDLLTRALTHSDNTANDRLLTYVGGP -RAVRAMIERKQLGDIRFGPGERLLQAAYTSDPPDGAAPLSIADALARLARGELLSETSTR -ILLDTMGASVTGRARMRAALPAGWTIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -STRPIRERQVLIQNVAAAVTT-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus contaminans TaxID=1343899 RepID=A0A553WBJ4_9SPHN ------NLLHEQWRLFPGKTGVAVMRIDGGDWViGRRLDELFPQQSVSKAWVAMTVLDQVD -QGKLKLDQKVRITIDDLAVHQPIRERVIANGESVLSLLEQAITASDNTANDSLLRTAGGP -QAVRAFIAKKRLGAIRFGPGERALQSRYLADPVDGASPEAIVRALAKLAKGELLSAASTR -LLLDIMSRTSSGPNRLKAGVPAGWRFLHKTGTGQSTGYNDIGIMTAPDGTRYAVVVMMGS -TTSSIPERMAFMQFVSRSVATY- ->[subseq from] Beta-lactamase class A n=2 Tax=Apibacter mensalis TaxID=1586267 RepID=A0A0X3APV5_9FLAO --qKLEKEIRSIIENKKATVGVAVIY-DSKDTL-TVNNDIEYPAASVFKFHQALALLDYMN -KNLLSLESKLYLKKSDMKNYSPLANEHPEGNISIGDLLSYTVSKSDNNASDALYYYMNGT -QMTDMYLRTLGSKKFSIEATEQELSQEFNNQYLNWTTPLEAAQLLNIFITKDIFCKNYKD -FLIQAMAKSETGSDKLKAFLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDPTNARMIADISTIVYKFy ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=root TaxID=1 RepID=A0A3E4N3M0_9BACE --qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TIENNRRYPLMSVFKLHQALAVGDYCK -RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTRTLFDKPHQE -FIKEALVTCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] Serine hydrolase n=1 Tax=Euhalothece sp. KZN 001 TaxID=1884791 RepID=A0A2K3BIN5_9CHRO ---TLKQTLQRLGSQSQLNPGAFIVDLDSGEYV-SLQGEKAFSAASMIKVPILIAFFHAWD -KGKLKLDERLTMTEEVKAGGSGNMQEAVGTEYLALETAAKMIIISDNTATNMIIKRLGGK -EALNQLFAEWGLEHTRLRNPLPDLEGT------NTTSAKELVELLAKLNQGKLVSARSRD -QIFRIMRETKT-RTLLPQGLGEGASIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER -PHND-RAANELIRQFSRETYQYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9SGJ7_9BACT --qKLESTINDIDRSLDGVIGVAILDLASGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ -TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE -DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VRNDSGVVFAEKR-PYVICVMTTY -LQR-ERDGEEAISRISLAAYRTf ->[subseq from] Class A beta-lactamase, subclass A2 n=2 Tax=Alistipes TaxID=239759 RepID=A0A3D1NSQ3_9BACT ---DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD -RNGLTPDTEIFIPEEELVPYSPLREEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP -AATDRYVRSLGLHDFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE -MIRQNLISCKTGADRLPKPLSTGAVIGHKTGTSDRDGTNDLGFVILPDGTRYTIAVFIKD -SAENPETNARIIADISETVYRY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Alistipes sp. TaxID=1872444 RepID=A0A3B9CLP9_9BACT --tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD -RNGLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP -TVADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE -FIIRTMTGCNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGRHYTIAVFVKD -SQESLQETERIIAEASDIVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Ant17 TaxID=1461752 RepID=A0A013XUW5_9SPHN ---RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID -AGQLALTDIVSRDVATMG---------PGAPLPVAQLLDLMLTRSDNNATDMLVARAGGP -SAVNAWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLIAAIRTGKALSPASTH -AFITIMERCRTGKARLSGMLPPGTTIAHKTGTIN-GTGNDTGVVTLPDGRMFAITVFVMQ -DHRGRVMRDRIMAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=A0A0Q4J826_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNEATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] serine hydrolase n=2 Tax=Sphingomonas sp. Leaf257 TaxID=1736309 RepID=UPI0009E894EB ------STINRLSASFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTVHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP -QAVRAMIAAKRLGDIRFGPGERLLQAAYVSDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWQIAHKTGTGQNAGFNDVGLLTAPDGRRFTIAVMIGD -TTEDIRKRQQLIQNVAAAVAN-- ->[subseq from] serine hydrolase n=1 Tax=Caenibacillus caldisaponilyticus TaxID=1674942 RepID=UPI000988386C ---TLQEKLEKVLADKPGTFGVAVRHLGTGESA-AINGDVLFQTASSCKVAILAALFHEAE -KGRLSLETRIRLSKSDLVPGSGVFQYDIGAEISVKDLATLMIIVSDNLATDKILEMV-GK -DNVNALTRALGLKNSRIEHTIWELLCFDMDRPNNVSTPEEMNRLLVLLAEGRLVSKAASA -AMIDILKKQQF-GHRLPYLLPDGATVAHKTGTIGS-VVNDVGIVYFPDQEGFAISVFSRG -CE-TAREAEQTIAELAKTAYDHf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_65_14 TaxID=1803459 RepID=A0A1Q7H548_9BACT ---RLRTHITQAMTEARGRMGVAIKHLESGTEV-VVNADEKFPMASTFKLPVLVTLYDRAK -KGQVKWDETVDVGVHDQHLGSGDLYDVPGVKLSLHNVANLMMMVSDNSGADICLTRA-GA -DNVNALMSSLGAGDIHVDRPTQELILKFAADARDQATPKAFVTLLEKMWRGEAVDKASSE -AMLETMKRCRTGAGRIKGLLPSNTTVAHKTGTIG-GVVDDVGIIYLPEEGHVAIAVLSKQ -TRATDVEVERAIAQIARYAYDYf ->[subseq from] ClassA n=14 Tax=root TaxID=1 RepID=A0A127SQY3_9BACT --qNMTQEIEKIIKGKQASVGVAIIH--NDDII-AIANEDKYPTMSVFKFHIAVTALKKME -AENIPLDKMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI -DKVDSYIKSLGIKDMNFTETEESMHTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA -FLETAMLDCVSGKNKLIAGLPTDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD -SRESDDDNAKIMADISNIVYRH- ->[subseq from] Putative beta-lactamase class A n=2 Tax=Sphingomonas parapaucimobilis TaxID=28213 RepID=A0A0A1W6Y4_9SPHN ------STINRLSAGFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP -QAVRAMIAAKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] Serine hydrolase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1B7W1B1_APHFL -----KNSLQTLTTASDLTPGVFLLDLDNGGYV-DINGNASFPAASTIKIPILMAFFQDVD -AGKIRLDEILTLEKEMIVGGSGVQYQTPGSKYTALDLATKMITISDNTATNMLVAKLGGQ -EALNGRFRGWGLTTTMIRNPLPDLGGT------NTTSPRELGNLISMVNQGTVVSMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADVGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. Sph1(2015) TaxID=1628084 RepID=A0A1R1Z0Q1_9SPHN ------STINRLSAGFAGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -RGRARLDEPIVVRREDLTLHQPIAMLVKGDGTTVGELLNRALTMSDNTANDRLLTYVGGP -QAVRAMIAAKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILIDTMEASRTGHARLRAAVPSGWTIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRKRQLLIQNVAAAVAD-- ->[subseq from] CME family class A beta-lactamase n=1 Tax=Elizabethkingia occulta TaxID=1867263 RepID=A0A1T3MZX1_9FLAO -htSILNDINAVTKDKKATVAVSVLGIENDFQFsNANGNLKMPMMSVFKFHITLAVLNQVD -KGNLTLDQKILIKKSDLLEWSPLREKYPNGNVPLSEIITYTVAQSDNNGCDILLRLIGGT -NTVQKLMDVNGVKNFQVKYNEEEMSKKVQAPYANYNTTASMVKTLKAFYKGVFLSKRSTA -FLMEIMTKTNTGMSKLPGLLP-KVRMARKTGSSGKMAENDSGIVTLGSGKHYAIAVFVKD -SMESEEVNCGMIAQISKVVWDA- ->[subseq from] Beta-lactamase n=1 Tax=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) TaxID=272123 RepID=K9ZMK7_ANACC -----KTDVQNLAAANNLTPGVFMVDLDTGAYV-DINSTASFSAASTIKVPILIAFFQDVD -AGKIRLDEMLTVQQEMIAGGSGTLQTTVGSQYTAIDVATKMITISDNTATNMLIARLGGQ -EVLNERFRSWGLATTIIRSPLPDLQGT------NTTSPRELGNLIAALNQGNMVSMRSRD -IMLDIMRRTQR-NNLLPSGLGEGAKSYHKTGDIGT-MLGDAGLIDIPTGKRYIAAVMVQR -PNND-PTAEKLISAISSAAYQHf ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=A0A1T3F3G6_9FLAO --pQLKKTLESIISGKKATVGVSVMSPDEKEMT-GINANQMLPMLSTVKFPLALAVLYEVE -KGKLSMNQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP -ETVQEFMDS---SSFIIKNDEEGMHKDWDSQFVNKITPNFAVLLLQEFSNGKILNKTNTQ -WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELLGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingosinicella sp. BN140058 TaxID=1892855 RepID=A0A4P6FPU1_9SPHN ------------------------------------------------------------- -------------------------------GVSAATLMEQMITRSDNRATDLLMNRLGGP -AAIDSWLRVRGIGGMRVDRTIAQLLSDRRKDIRDSSTPAAMLNLLRMLDTQPVLKPESRL -RLLDLMARCKTGSNRMRALLPAAVKVEHKTGTLT-GYTGDVGFLTLPSGRRLAVAFFARG -GS----NRPAVIATAARAIFDAf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. NIC1 TaxID=1961362 RepID=UPI0007C0D80B ---RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -SAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFSETSTR -ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQAVAAAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroidales bacterium TaxID=2030927 RepID=UPI0011CAD63E --qNLTQEIEKVIQEKQASIGVAVMY--GDKTF-AVANHKKYPIMSVFKFHIAVTALKKME -TENIPLDSMIYIEPKQIHKFSPLRDKYPNQRLSYRDMIEYTVAHSDNNTCDLLIEFVGGI -KNVDTYIKSLGIKDLNLTETEHDMHENIMNCYNNWSTPLSIAQLLKKVYTENILTEDHFT -FLEKIMLNCSSGKDKLKAGLPADIKIAHKTGHSDRTSEADAGVIYLPNGEKCYIVVLIKD -SRESDKDNAKIMADIANLTFRI- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=A0A0P0GLD1_9BACE --qKIEQQIDSFLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDTDNAAIIASISKIVYDT- ->[subseq from] Uncharacterized protein n=1 Tax=Rheinheimera sp. TaxID=1869214 RepID=A0A349LW26_9GAMM ----------------YARVGIYLLDLQQAQAW-SLNNNPSYPLLSSFKLPLAIWVLKLVE -TGQLSLEQAVPIQRSALMQWSPLLDEHKAANLTVRELLRYSVELSDNNAADVLLQLSGGT -AALQQYLQQQGLQNTVIQATEQQMHQGFAAQYRNHSRPSDMALLLAQLANTELLHAEQSD -LLVQWLRDTPTGAKRVKAGLPDGSIWLHKTGTSGRAAVNDIGLLQLPDGRQFVLVMLVQD -SHWSLDDTEALMARLTARLV--- ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Pan181 TaxID=2527972 RepID=A0A518AS84_9BACT ----LEKLVLPLIENHRGEVGVMIRFLPTGETF-AYRADQAMPTASLIKFPIMMATYKAIH -EGKLKLEQPITLKEDDQVPGSGVLTTHFSPGLSLRDAIQLMIAFSDNTATNLVIDQV-GI -EETNRLMESLGCDETRLNSKVYRRDTRSQKYGLGSTSCRDMIQLAELVSNDEFLGKEDCE -QILKHLYDCTA-KSGVPRLLPESIRIAHKTGSVGD-SRTDAGLIDTPKGK-IAFCVLTTK -NDDDSNEAELLAAEIGLIAYNYf ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A6B1AJP0_9BACT -----GESLRRIARRVGDAVGVSALHVESGARI-SFNGDRPYPMASVSKVPMALEFLRRVD -LGEIDPAETVVVTVEEFRPHSPLAAWSGARSLTVDSLFSLMLGQSDNTATDVILNMSGGP -EAATRHLRRLGVEGVRVDRSEARTFARYGADPRDTATPEGMTDLLLTIHEGKELTPESRA -WILDVLNRSRSGRGRMRGRLPQSTFVAHKTGTMG-GAINDVGIVTLPDGGHLIVSVFVNT -LRRPTWRRERTIAEMTRLLYDYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=UPI0009E8C6AA ------------------------------------------------------------- ----------------------------------AAKVMALMIIRSDNQATDQLLAALGGP -VAVQQWLSSHNIPGIRMDRTIAQLLRGHLADSRDVSTPVAMVTLLNKLDNGTVLTAQSRA -LLLDLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] serine hydrolase n=1 Tax=Novosphingopyxis baekryungensis TaxID=279369 RepID=UPI0012EB2C46 -----VSEVNALWRGFPGTTGIAVRRIDGDWSF-GERKDELFPQQSVSKTWVTLTILDQID -QGKLRLSDPVTITVADLAVHQPIRDRVIANGETVGSLIEQAITKSDNTANDALLWKAGGP -DAVRDFISRKNLGAIRFGPGERLLQSAYLRDPMDGASPQAIVDALAKLARGELLSPASTQ -LMLSTMSRTSSGPNRLKAGVPGGWNFLHKTGTGQSTGYNDIGIMTAPDGTRYAVAVMLGD -TTASIPERMRLMQAVSRAVARY- ->[subseq from] Beta-lactamase n=1 Tax=Anabaenopsis circularis NIES-21 TaxID=1085406 RepID=A0A1Z4GAT6_9CYAN ---SLKNNVQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDVVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGLTTTSIKNQLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD -IMLDIMRRTER-DNLLPSGLGSGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR -PNND-PRAEKFISSISRTAYE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522QUU7_9BACT ---SLRQQIASICESKHAIIGVYVQVIESGDTL-SFNGIKHFPMQSVFKFPLALYILSQVD -KGKLSLNQRLFISKKELLPWSPLRDSHRGGNMTLRDLLQYTISHSDNNGCDILFRLAGGP -DKVNHYIHGLGMKNISIKTTETQMHSAWNVQFSNWATPVAVTKLLVLFYNGKILSPASRD -FLLKMMEGTTTGANKIKGLLPSGTLVAHKSGLSDR------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-1A-559 TaxID=2135657 RepID=A0A4R2SS28_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNQATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-17 TaxID=2013663 RepID=A0A2N3CTD9_9PROT ----LAERIHFLWRGFPGKTGIAVQRIDGEWAV-SQRGGELFPQQSVSKLWVAMAALDAVD -QGRLRLDQQVRIGPEDLTLYQPLAARVRSEGMSVRALIETAITQSDNTANDSLLRTIGGP -TTVQSFLARKNLGAIRFGPGERQLQSRYLADPVDGASPDAIASALTRLARGALLSPESTE -YLLGVMSRTRSGPNRLKAGLPSDWKFLHKTGTGQTAGYNNIGIATAPDGTRYAIVVLMGT -TTSPIPSRMALMQAVSGAVAE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=Q2LA82_ACIBA ----LKEQIESIVIGKKATVGVAVWGPDDLEPL-LINPCEKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDEVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLV------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aurantiacus TaxID=1463599 RepID=UPI00132C2E94 ---AFEKRIAELADGSRGRIGISAVDLSTGYHL-DILGDQRFPMASTSKIAIAATFLEGVE -KGRWSLTSEFPLLVPQRSASSTVAPVSTGKHLPAIQLIELMITRSSNPATDALLRVVGGP -VAVNNWAARNGIREFSLDRDIATLVRATYIDRRDSATPTAMTDLLTALYRGTTLSDSSRS -VILGAMSRTVTGKRRIKALIPSEASVSNKTGSLNN-TSSDIGYIETPDGRTIALAIYVTG -QG-SRAQREAKIAQLARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium ST_bin13 TaxID=1978761 RepID=A0A1W9JKQ8_9PROT ----LSASINAVRAQFDGTVGIAVRSVDKGWSV-ATNGDLKLPQQSVSKLWVAMTVLDARD -SGRLTLDDPVTVTREDLTLHQPIAAMVTGDGATVGELLQRALTTSDNTANDRLLRYVGGP -EAVRAFIKRKGLGAINFGPGERLLQSSYVSNPPDGAAPSAIAGALAMLKKGELLSSPSTS -YLISTMESSKTGRQRLRGAVPEGWRFGHKTGTGQTAGYNDVGILTAPDGQSYTLAVMIGD -TPRPVTERQALMQSVVASVVAY- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00124A601F ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTA------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011C995C0 -----------------------ALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNEVAFIYPKNQ----------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15 TaxID=1802170 RepID=A0A1G3JWU9_9SPHN ---RLIAQFQRFATLTDGTVGITVRDLASGETL-SLNGNTLFPMASAYKVAVAGKIFAMID -AGQLALTDIVPRDV---------ATMGPGAPMPVARLLDLMLTQSDNHATDMLVARAGGP -TAVNGWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGNALSPASTH -AFITIMERCRTGKTRLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ -DHRGRVMRDRIMAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=A0A0Q4F639_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNQATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Beta-lactamase n=4 Tax=Bacteroides TaxID=816 RepID=A0A174U954_BACVU --kTLKTEIRHIIKDKKATIGVALI-LDGEDTL-AINNAEKYPMMSVYKFHQALAVCDYLQ -KRHIPLSTSLYLDKKYFKPYSPLRDKYPQGNLPISELLVYTMQSSDNVACDILFDYIGGV -NVVDEYIHSLGINDVSITATEDEMHQDMDDCYKNWTTPMEAANLLEVFMTQDFMRNEYTD -FLKHIMIECGTGKDRLPAPLPSEVKIGHKTGTSDKNGINDIGFVILPDGSRYVVAVFVKD -SKENMETNAKIISDISAAVYRY- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E4HU16_9BACT ---RLRGALLAIAQRFPGDVGVYVHHIESGMET-GVDEDTPYGMASTYKVPILVELMTRVE -AGDLRLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA -DQITARMRSLGFQNIRVDRTTLELILAFYGGDKDKASARDMTELLVMISEGTAVSRGSSE -VIMEILSRTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGDGRFAISVFTLG -NEADTELGEDTIAEMARTAYDFf ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. JV274 TaxID=1932669 RepID=UPI000985B683 ---DLKKTIESIISNKKADVGVSIIGPDQKETI-QINGNTLYPMLSTVKFPIALTVLKKVE -KGELSLQQKLFIKKEELLEWSPFKKEHPEGNISLEEALKWIVSYSDNNISDILMRLVGGS -EPVQQLVNS---KDCIIQNNEEDMHKDWESQFVNKITPNEAIRLLTAFSNGKILNKEHSL -WLYNIMLNNTAGPKRLKGSLPPQVKVAHRTGTSFTGAINDFGIIELSDNKKIYIAVFVHD -TYEKFENAEAIIADISKATYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Sulfopaludibacter sp. SbA4 TaxID=2043165 RepID=A0A2U3LW36_9BACT ----LTRQWQRIASGTDGVVGAAALHLNSGRHA-SLHGGERFPLASVCKLPIAIAILAMAG -EGKLSLDDQIEIPLQDVVPVSIVAERWPGQKFRLNELLEWMVAKSDNSAVETLFRMSGGA -AGMAARFLQWQVEGMRVDRSERECALRFMADPRDTATPDGTVHLLQRAFRGELLSASLTG -RLVEILEAATTGSARIKGLLPAGTVVAHKTGTTANGGTNDVGVITLPKGGQLAIAVYVKG -STRDLATREKIIAGIARSAF--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9TGZ4_9BACT --qKLESTINDIDRSLDGVIGVAILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ -TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE -DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VRNDSGVVFAEKR-PYVICVMTTY -LQR-ERDGEEAISRISLAAYRTf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter sp. TH134 TaxID=2067450 RepID=A0A2N4WYK2_9SPHN ---SFEQRIADLANPAMGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAGTFLEMVE -QGRFSLTSEFPLMLPVASAYSSAKAPRPGQYLPAIDLIEIMITRSSNPATDALLAAVGGP -AVVNDWIRRQGIAEFSINRDIATLVRAVHIDTRDAATPRAMVRLLAGLYRGDFLSDQSRQ -VLLSAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGLIECPDGRVIAVAIYVTG -QG-TKLAREERIAAIARALYDGf ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf25 TaxID=1735692 RepID=A0A0Q4IFW8_9SPHN ---ALVQAINALGGGFQGHVGIAVRSIDDGWVV-GHAMDRRMPQQSVSKLWVAMTTMSAID -EGRLALTTPVAITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLVGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLSQQSTA -WLLDTMAHTRTGRARIRAALPPGWSVAHKTGTGQTAGFNDIGIITAPDGKAYAIAVMIGD -TARPVPERQQLIQTVVSSIV--- ->[subseq from] serine hydrolase n=1 Tax=Planktothrix paucivesiculata TaxID=1678308 RepID=UPI0012DDC1A3 ----LKTAILGLAKDSKLKPGVFLVDLDTGKYV-DIQGQEAVPAASTIKVPILVSFFQAVD -EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRQISSTIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera malacea cyanobiont' DB3992 TaxID=1206980 RepID=A0A2D0HEL8_9NOSO --kALEPQIKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSRLVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Dysgonomonas alginatilytica TaxID=1605892 RepID=A0A2V3PRU2_9BACT ---ELRKNIGSIIENKNATVGVAII-FNGKDTL-TVNNQYRYPTMSVYKFHQALAVLDNLN -RRNLPLDQQIYISKSALQPHSPLRDARPEGNMPIKELLQYSVSQSDNNACDILFSFLGGT -DYVEKYIKSLGIMQIAITATEKEMHDDHSKQYANWTTPYSAVELLEKFRQDDWFPPKYKN -FLWESLIDTSTGQDKIKALLPPNTVVGHKTGTSFRNADNDLGFIELPNGKQFSIAVFIVN -SIEDDKTNATIIAQISKAAYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes onderdonkii TaxID=328813 RepID=UPI000A05ED1A ---QFESRLDEIVSGHKAFVGVAIR-TPDGKTV--ARNDSLLPMMSVFKFPVALAVLDRMQ -REGTPLTQPISITPDLLLPYSPMRDSLPESGLTLGQLLRYTVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGICIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCEATTGTNKLKAGLPAGTVIGHKTGSSDRTADNDAGYVLLPDGCRYCIAVFVTE -SEENDAANAAIAAAVSRAAYEYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas bacterium TaxID=1895847 RepID=A0A3D0W9Y7_9SPHN ------TDIDGLVGAFGGKVGVAVKSIDTGWMV-SKNGDVPMPQQSVSKLWVTLTAMDQID -QGRITLDDPLTITRNDLTLHQPIASLLQNGVTTVRELIRRAMTMSDNTANDRLLRHVGGP -PAVNAFIARHSLGAIRFGPGERLLQSAYVANPIDGAAAASIANALTKLRRGELLSPQSTS -YLINVMESSRTGHARLRASVPPGWRLAHKTGTGQTAGFNDVGILTAPDGRAYAIAVMIGD -TRRPTQERQKLMQNVVARVVAY- ->[subseq from] CepA (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SIF1_9BACT ---DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD -RNGLTPDTEIFIPEEELVPYSPLRKEFLGGELSVSRLLEYSLQLSDNNACDILFKHTGGP -AATDRYVRSLGLHNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE -MIRQNLINCKTGADRLPKPLSTGAVIGHKTGTSDRDGTNDLGFVILPDGTRYTIAIFIKN -SAENPETNARIIADISETVY--- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7IS84_9NOSO ----LEPQVKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILMAFFQDLD -AGKVTLEEKLTMRRDLVTNGSGTMQESVGKKYTALETITKMITISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPPSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-SRGRDFIRQVSRLVYDY- ->[subseq from] serine hydrolase n=1 Tax=Nostoc piscinale TaxID=224012 RepID=UPI0009F83437 ----LKNAVQNLAATTDLTPGIFLVDLDNGGYV-DINAAVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNFQKPIGTQYSALEVATKMITISDNTATNMLIARLGGI -DALNQRFRSWGLTTTVIKNKLPDLQGT------NITSPKELGNLMAMVNQGNFVSLRSRD -IMLDIMRRTER-DHLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR -PNND-PRAEKLISSISRITYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sporomusa malonica TaxID=112901 RepID=A0A1W2CWH1_9FIRM ----LHQKIQAILAQYTGRSGIVIINQNTGARL-ELHPDMVFPAASMIKVPIMIEVMRQAA -AGLIDLDETLEITSQVQTGGAGILKELRSGVMTVRELVTLMIILSDNTATNILIDLV-GM -NSINATITSLGLRSTVLRRKMMDFEAA-KAGKENYTSAADLAHLFASIASSSALPPTHSA -LMLDILKRQQV-RDKLPFYLPEEIIIAHKTGTLP-GAEHDAGILFVPGG-SYIICVLTAD -LAAN-YEGLQLVANIGKTIYDY- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas japonica TaxID=511662 RepID=UPI0011211A98 ---ALVTTINGLADAFGGRVGIAVKSIDDDWMV-AKNGELALPQQSVSKLWVAMTTLDALD -KGRISLDQSVTITRSDLTLHQPIAALVKDGGTTVRDLLQRAMTRSDNTANDRLLKLVGGP -ASVNAFIADRNLGNIKFGPGERLLQAGYVANPPDGAGAAAIANALARLQRGDLLSPASTR -WLISTMESSKTGRARLKAGTPAGWSLGHKTGTGQTAGFNDIGILTAPNGKSYAIAVLIGD -TSRPVPQRQELIQNVAAAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingopyxis sp. L1A2A TaxID=2502247 RepID=UPI0010F812A1 ----LTERIHFLWRAFPGKTGIAVQRIDGEWAI-AERGGDLFPQQSVSKLWVSLTALDAVD -QGRVRLDQPVRIGPEDLTLYQPLAARVRAQGMTVRQLIETAITQSDNTANDSLLRTIGGP -GAVRAFMAKKDLGAIRFGPGERLLQSNYLANPIDGASPTAIASALARLARGTLLSPESTD -YLLGVMSRTKSGPKRLKAGLPPGWKFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGT -TTSPIPARMALMQAVSSAVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingopyxis sp. YR583 TaxID=1881047 RepID=A0A1H6G6X8_9SPHN ----LNDRIFELWRAFPGKTGIAVQRIDGEWSL-SQRGAELFPQQSVSKLWVTLSVLDAVD -QGRMTLDQRVRIGPEDLVVHQPLAARVRSEGMSVRDLIETAITHSDNLANDSLLRTVGGP -NAVRAFITKKDLGSIRFGPGERLLQANYLANPVDGASPSAIASALTRLARGTLLSPKSTE -YLQGVLGRTKSGPRRLKAGLPPGWQFMHKTGTGQTAGYNDIGIATAPDGTRYAIVVMMGS -TTASIPARMALMQSVSSAVAEY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 28-62-20 TaxID=1970433 RepID=A0A258SCG0_9SPHN ----LSASINAVRAQFDGTVGIAVRSVDKGWSV-ATNGDLKLPQQSVSKLWVAMTVLDARD -SGRLTLDDPVTVTREDLTLHQPIAAMVTGDGATVGELLQRALTTSDNTANDRLLRYVGGP -DAVRAFIKRKGLGAINFGPGERLLQSSYVSNPPDGAAPSAIAGALAMLKKGELLSSPSTS -YLISTMESSKTGRQRLRGAVPEGWRFGHKTGTGQTAGYNDVGILTAPDGQSYTLAVMIGD -TPRPVTERQALMQSVVASVVAY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides cellulosilyticus TaxID=246787 RepID=UPI001230F4B9 --qKIEQQIDSLLKDKKATVGVAVLA--NDETVaVYNNQIHFPLLSVFKYHVGLTVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNITDKQILFGTQYKD -FLQATMQETSTGKDKLKGQLPADVIVGHRTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Candidatus Aminicenantes bacterium RBG_13_63_10 TaxID=1797270 RepID=A0A1F5B941_9BACT ---RLRAQLERLWRNRDGTAGIAVKHLESGREL-LINADDLFPLASVFKLPVLVELMAQVR -EGRLSLEDEIDLVPADLHLGSGVLADLVAPGLSVRNLILLMMTVSDNSAADLLLAKV-GV -ENVNRRLRGLGIEGISVSRSCQELILSFSLQEEDRSAPRAMNVLLERVFRKNILDEASCQ -TILDIMAKCQTGAGRIKGRLPSGTEVAHKTGTLS-GSFNDCGIIFLPDGGHVALSIMTKD -FHMRSADIESLIAETAKFVYDFf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=UPI0009E9CE1D ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNEATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Beta-lactamase n=2 Tax=Sphingorhabdus sp. 109 TaxID=2653173 RepID=A0A653JK83_9SPHN ---ALVQEIEQLWRTFPGKTGIAIKRIDGEWEF-GHRIDEYFPQQSVSKLWVAMTMLDKID -QGRASLSDPIRIGKEDLTLHQPMAVEVEREGKSVYTLLEKALASSDNTANDALLRHAGGP -EAVRKFIDKNNLGKIRFGPGERLLQAAYLADPVDGASPRAIVHALDKLARGELLSANSTK -LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQATGYNDIGIMTAPDGTRYAVVVMLGD -TTASIPERMRMMQAVTRAVGR-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. LMO-1 TaxID=2681549 RepID=UPI0012E6F584 ----LLSEIERLGRGFDGVVGIAVRDVQAGWSV-SWNGTGRFPQQSVSKLWVALTLLDAAD -HGVLRLDDPITVRRTDLTLHQPVRAMMGPDGTSIRNLLTIAMTQSDNTANDVLLKRVGGP -GAVRAFFTRAALPGIAFGPGETLLQSRYLADPMDGAQPEAIAAALARLRKGDLLSPSSTQ -TLLSIMASSKTGPQRLKGGLTEDWAFAHKTGTGQATGYNDVGLLTAPDGRTFAVAVMIAS -TRQPIPVRMRMMQGVTRAVI--- ->[subseq from] Serine hydrolase n=1 Tax=Chroococcales cyanobacterium IPPAS B-1203 TaxID=2049454 RepID=A0A2G7GTP6_9CHRO ---SLKTTVEQLAAQKNLLPGVFFVDLDTGGYL-DVNGNTTFAAASMIKVPLLVAFFQDVD -AGKIRLDESLTLKKELIGGGSGDMQKPLETKFTALETATKMIVISDNTATNLLIERMGGV -AALNERFLSWGLTATQIRNLLPDLEGT------NTTSPKDLAHLMALVNEGDLMSMRSRD -RMLDIMQRTVT-NTLLPRGLGEGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIAVAMVKR -PHND-GRAQELIRQISRAAYQE- ->[subseq from] Beta-lactamase n=1 Tax=Alistipes sp. CAG:157 TaxID=1262692 RepID=R5X4P2_9BACT --tELEQALRTLVERKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD -RNGLPLSTPLPIWESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGP -TAADRYIRTLGIEGFAVEATEEEMHRDLTACYRNWSHPLDAARLLEMLITRPLFRDASQE -FIIRTMTECNTGPERLPKPLATGAVIGHKTGSGDRNGTNDIGFVQLPDGRHYTIAVFVKD -SQESLQETERIIAEASDIVYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chryseobacterium gleum TaxID=250 RepID=A0A1S7SKH9_9FLAO ----LEQKINSILKNKKATVGVSVLGFENGFKY-DKNGDKKLPMQSVFKFHIAAAVLNAVD -QGKLSLHQKIMLNPSNLLEWSPLRDKYPAGNIPLSEVIEYTVAKSDNNGCDILLRLLGGT -QVVQKFMDSKGVKGFQIKYNEEDMHKDWNVQYENYSTTKSAADVLKKLYDGKLLSKKSTD -YLMKVMLSTSTGLNKMVEQLPKNTPVARKTGASGTGAENEIGIVTLPNGKHYA------- ------------------------ ->[subseq from] Penicillin-binding protein n=1 Tax=Nostoc piscinale CENA21 TaxID=224013 RepID=A0A0M4SVF8_9NOSO ----LKNAVQNLAATTDLTPGIFLVDLDNGGYV-DINAAVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNFQKPIGTQYSALEVATKMITISDNTATNMLIARLGGI -DALNQRFRSWGLTTTVIKNKLPDLQGT------NITSPKELGNLMAMVNQGNFVSLRSRD -IMLDIMRRTER-DHLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR -PNND-PRAEKLISSISRITYE-- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia ursingii TaxID=1756150 RepID=UPI00099A52B1 --sQLKKTLESIISGKKAIVGISVMSPDEKEIT-GINANQMLPMLSTVKFPLALAVLYEVE -KGKLSMNQKLFIKKEELLSWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP -ETVQEFMDS---SSFLIKNDEEGMHKDWDSQFINKITPNFAVLLLQEFSNGKILNKTNTK -WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDNSEKIISDIGRAAYDYy ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000E489485 --qNMTREIEKIIKGKQASVGVAIIH--NDDII-TIANEDKYPTMSVFKFHIAVTALKKME -AENIPLDEMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI -DEVDSYIKSLGIKDMNFTETEESMHTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA -FLETAMLDCVSGKNKLIAGLPNDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD -SRESDDDNAKIMADISNVVYRH- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2D6SWQ8_9PLAN ---ELKALLAPLIEAHQGKVAIAIKHLETSETF-DHRADEPMPTASLIKFPVMAEAYRQAE -QGRVELEGLIALREDDKVPGSGILTTHLSAGLSLRDAIRLMIAYSDNTATNLTLEAI-GI -RSTAEFMESLGMPNTKIHAKVFRRESVFPQRSRGSTTAAETLRLYELLHQRKLVSAAASD -KMRDHLLHCTD-DEKMARLLPPGTKVAHKGGAVSR-ARCDAGIIYSPSG-PLVVCVMTSE -NEQPENAGSRLCADVARVAFEHf ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides TaxID=816 RepID=UPI000E52BBF2 --qNMTQEIEKIIKGKQASVGVAIIH--NDDII-AIANEDKYPTMSVFKFHIAVTALKKME -AENIPLDKMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI -DKVDSYIKSLGIKDMNFTETEESMRTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA -FLETAMLDCVSGKNKLIAGLPTDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD -SRESDDDNAKIMADISNIVYRH- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. KC8 TaxID=1030157 RepID=UPI00111055E3 ---ALETRVAELGRAFPGSVGIAVRDVTTGWSV-GYNATRLMPQQSVSKLWVAITVLDAVD -RGAIKLTEPVVVRRENLTVHQPVRAMMGKDGTTYGDLLRIALTQSDNTCNDMLMRRAGGP -DAVRSMISRKGLGQIGFGPGETLLQSRYLADPMDGASAAAIAAALARLERGELLSRGATR -TLIGTMRDSRTGPQRLRAGLAPGWSLAHKTGTGQATGYNDVGLVTAPDGRTYAVAVMIAS -TRQSIPVRQRLMADVVRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium 13_1_40CM_55_7 TaxID=1805079 RepID=A0A1Q7F6S9_9CHLR --qKLESTINDIDRSLDGVIGVAILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ -TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE -DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VRNDSGVVFAEKR-PYVICVMTTY -LQR-ERDGEEAISRISLAAYRMf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWC2_64_44 TaxID=1797935 RepID=A0A1F9TFA4_9BACT ---NMTASLDKLASGYRGHVGIYLKDLNSGRVW-QHNPDRLFPSASLIKVPIMVSILSKIK -SGELSLETRMKLTRRDRAGGSGSLKWAREGTLSVTEILFKMITESDNTATKMLIANA-GI -DYLQRAFGELGLVHTGIFQEGMSLASG-RVERENYTTPREMAGLLERIYLGEIVDAASSE -YMLDVLKHNNKSRTRLRKALPPGWELGHKTGLLRR-SCHDVGIVFSPRGD-YVIAVLTGE -VP-DYASAKNFIARVARSTYEYy ->[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=[Oscillatoria] sp. PCC 6506 TaxID=272129 RepID=D8FTX3_9CYAN ----LKAEIDKLAAQNNFTPGVFIVDLDTGGYA-SVSSDAAFAAASTIKVPILVAFFQAVD -EGRVRLDQVLTLRPEHIASGSGELQDSPGTKYTALEVATKMIAISDNTATNMLIELLGGA -EALNQQFQTWGLTVTAIRNNLPDLAGT------NTTSPKELVNLIGQINQGGLVSLRSRD -RLLYIMRQTQN-DSLLPRGLGEGAIIAHKTGNINS-LVADAGMVDMPSGKRYLVAVMVKY -AK-NEKGADKLIRDISRTTYEYf ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014473738 ------NTLQTLTTNSDFTPGVFLLDLDNGGYV-DINSNTSFSAASTIKIPILIAFFQDVD -AGKIRLDEMLTLEKEMMVGGSGNMQYTPGSKYTALDLATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTATMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD -LMLNIMNRTER-DNLLPAGLGKGANTYHKTGDIGT-MLADAGLVDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Class A beta-lactamase n=1 Tax=Coprobacter sp. TaxID=1941478 RepID=A0A316SPR3_9BACT --qNLTQEIEKVIQDKQASIGVAVMY--GDKTF-TVANHKKYPIMSVFKFHIAVTALKKME -TENIPLDSMIYIEPKQIHKFSPLRDKYPNQRLSYRDMIEYTVAHSDNNTCDLLIEFVGGI -KNVDTYIKSLGIKDLNLTETEHDMHENIMNCYNNWSTPLSIAQLLKKVYTENILTEDHFT -FLEKIMLNCSSGKDKLKAGLPADIKIAHKTGHSDRTSEADAGVIYLPNGEKCYIVVLIKD -SRESDKDNAKIMADIANLTFRI- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Saccharicenans subterraneum TaxID=2508984 RepID=A0A3E2BMM5_9BACT --kRLRDQLAATRDSLDGVLGLAVRDLSSGQSL-FINENEIFPQASSIKIAILLEVLKQAE -ENRLKLEEFVDLKPESKVGGGPILNYYPSLKISIRDLCVLMVVLSDNTATNLLIDRV-GM -ETVNDRLTSLGLKQTQLRRKMMDLRAA-EEGRENISTPREMLTLLDRVWQGKVLGPEHRQ -LFFDLLSLPKD--SPLQQAVPEGITVADKPGELE-AVRCDSGLVFLKKR-PYIICVMTTY -LAP-TEDGNAVIRKIGRQVYNHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella humi TaxID=2068657 RepID=A0A2U2J5Y8_9SPHN ----LDARINELGRAFNGDIGIAVKDIQTGWTS-HYDGTTWYPQQSVSKFWVALTALAEVD -KGNLSLATPVTLGRDDLTLHQPIRAMVLSGGTTPNDLLHRAIQQSDNTANDFLLWRAGGP -EAVRAYLDRMNIEGIRFGPGERALQSSYIANPMDGATPLGIVDALARLKKGELLSPSSTA -LLLEIMSNTRTGPTRLKGGLSGGWRLAHKTGTGQQAGYNDIGIVTSPSGHSYAVAVLIRR -TSAPNIQRMRTMQDTVRAIIDY- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A4U3BDQ2_BACCE ------------------------------------------------------------- -----TLNEVITFTKEDLVDYSPVTEKHVDTGMKLGEIAEAAVRSSDNTAGNILFNKIGGP -KGYEKALRHMGDRITMSNRFETELNEAIPGDIRDTSTAKAIATNLKAFTVGNALPAEKRK -ILTEWMKGNATGDKLIRAGVPTEWVVGDKSGAGSYGTRNDIAIVWP-------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonas sp. KC8 TaxID=1030157 RepID=A0A1X9YEH5_9SPHN ---ALETRVAELGRAFPGSVGIAVRDVTTGWSV-GYNATRLMPQQSVSKLWVAITVLDAVD -RGAIKLTEPVVVRRENLTVHQPVRAMMGKDGTTYGDLLRIALTQSDNTCNDMLMRRAGGP -DAVRSMISRKGLGQIGFGPGETLLQSRYLADPMDGASAAAIAAALARLERGELLSRGATR -TLIGTMRDSRTGPQRLRAGLAPGWSLAHKTGTGQATGYNDVGLVTAPDGRTYAVAVMIAS -TRQSIPVRQRLMADVVRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Porphyrobacter sp. CACIAM 03H1 TaxID=2003315 RepID=A0A2Z2P425_9SPHN ---SFEQRIADLANPAMGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKIAVAATFMELVE -QGRYSLTSEFPLMMPVASASSARAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP -QAVNAWMQRKGIAPFSINRDIATLVRATHIDTRDAATPRAMVRLLAGLYRGEYLSDESRR -VILSAMSRTVTGKRRIPAHIPLEARVSHKTGSLNN-TSSDIGLIECPDGRVIAVAIYVTG -QG-SKLAREERIAAIARALYDGf ->[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. PCC 7107 TaxID=317936 RepID=K9QG58_9NOSO ----LKNTVQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI -EALNQRFRSWGFTTTIIKNKLPDLQGT------NITSPRELGNLMAMVNQGNFVSLRSRD -IMLDIMRRTER-DNLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISVMVKR -PNND-PRAEKFISSISRTAYE-- ->[subseq from] HGF-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0E9_9ZZZZ -------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAVLKKMD -REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI -KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA -FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN -SLESDETNARIMADITRVIYH-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella humi TaxID=2068657 RepID=UPI0011B23140 ----LDARINELGRAFNGDIGIAVKDIQTGWTS-HYDGTTWYPQQSVSKFWVALTALAEVD -KGNLSLATPVTLGRDDLTLHQPIRAMVLSGGTTPNDLLHRAIQQSDNTANDFLLWRAGGP -EAVRAYLDRMNIEGIRFGPGERALQSSYIANPMDGATPLGIVDALARLKKGELLSPSSTA -LLLEIMSNTRTGPTRLKGGLSGGWRLAHKTGTGQQAGYNDIGIVTSPSGHSYAVAVLIRR -TSAPNIQRMRTMQDTVRAIIDY- ->[subseq from] class A beta-lactamase n=1 Tax=Elizabethkingia miricola TaxID=172045 RepID=UPI0009998CAB ----VKKTLESIIYGKKATVGISIIGPDTKDVT-QINGDQMLPMLSTVKFPLALTVLHEVE -KGKLSMDQKLFIKKEELLEWSPFKEKYPQGNITLEEALKWTVSYSDNNLTDILLRLIGGP -ETVQEFIDS---SSFIIKNDEEGMHKDWDSQFINKITSNYATLLLQEFSNGKILNKAHTQ -WLYNAMLNNASGKKRLKGNLPAGVKIAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A TaxID=2014529 RepID=A0A235IE17_9NOSO --kSLEPQIKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQNLD -AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKHYLAAIFVTR -PYKD-TRGRDFIRQVSRLVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 32-66-10 TaxID=1970437 RepID=A0A258H6U6_9SPHN ---ALTATVDALARDFGGVVGISVRSLEWGWQV-DANGDRRMPQQSVSKLWVAMTVLDARD -KGRLTLDDPVELRREHLTLHQPIATLVVRDGTTVRELLLRAMQQSDNTANDRLLTLAGGP -QAVRAFIAERGLGEIRFGPGERLLQASYVADPVDGAAPSAIALALARLKAGELLSASSTS -FLTNVMSGTRTGKARLRAAVPVGWTLAHKTGTGQTAGFNDIGILTAPDGKAYSVAVMIGD -TPRPVRERQQLMQAVVASVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MKG4_9BACT ------------------------------------------------------------- --------------------------------MTLGALCAAAIEQSDNTAGNLLLDTIGGP -VGLTNFARSVSDETTRLDRKEPELNSAIPGDERDTTTPAAMCADMQHFLLGNVLSESSQN -QLQDWLPQNETGSLMIRASVPKTWTVGDKTGRCGNGATNDVAIIRPPGRAPILVAIYSIG -STSSADDRAAIVAEPARAVVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3TAI9_9CAUL -----------------------------------------FNYCSTFKLFLAAATLERAQ -RGDERLDRAVAISSGDLVSHAPVTGAAVGGHLTIQDLCQATVEVSDNPAANILIREMGGL -DAWRGWLRSIGDADTTIDRLEPGLN--VPDGAKDTAHVDQTVTNLQAVLKEGRLDQAHSA -LLRRWLVDSPTGAGRIKAGAPVGWTVAHKTGTGGGGQVNDIGLLEGPNGQRVFLAIYYDG -PSKPAAEADAVVAEATRIS---- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. MBR 210 TaxID=1881015 RepID=A0A1C0UWE4_9NOSO ----LKNAVQNLAATTDLTPGIFLVDLDNGGYV-DINASVGFPAASTIKVPILVAFFQDVD -AGKIRLDEMLTMQQDMVAGGSGNFQKPVGTQYSALEVATKMITISDNTATNMLIARLGGI -DALNQRFRSWGLTTTVIKNKLPDLQGT------NITSPRELGNLMAMLNQGNFVSLRSRD -IMLDIMRRTER-DNLLPSGLGAGARIYHKTGDIGT-MLADTGLVDIPNGKRYIISLMIKR -PNND-PRAEKLISSISRTTYE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JFA9_SPHSX ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNQATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas faeni TaxID=185950 RepID=A0A2T5U9A4_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNQATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. PAMC26645 TaxID=2565555 RepID=A0A4P7QZ09_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNQATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Putative beta-lactamase n=1 Tax=Erythrobacter sp. NAP1 TaxID=237727 RepID=A3WBM5_9SPHN ---AFEQRLEEIGASLTGTVGIAVQDVETGELY-EFNGDELLPQQSVTKLWVAMAALSQVD -QGDLNLTERVRIGRDDLTLHQPVREIVKARGTNYRDLFERSITRSDNTANDRLLRRIGGP -DAVQQWLDDKGLTGIRFGTDERSKQSGYLADPIDGASANAIASALTKLARGDLLDTDTTR -LLRDTLEQTRSGPRRLKGGAPEGWRVEHKTGTGQQSGYNDVGILTSPDGREYAIAVLIGR -TSEPTPARMEMMQQVTSATAQ-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. T09 TaxID=1932621 RepID=A0A252DE48_9NOSO --kALEPQIKALMNRYSLQTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRRDLVTNGSGVMQERVGKKYSALETVTKMVTISDNTATNMIIDHLGGA -AKLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE -QALDILRHTSI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Undibacterium pigrum TaxID=401470 RepID=A0A318JEI3_9BURK -----QNVIESIAIDSGGRLSASLLVLETGQSL-WILPDQAAPMQGVSKLPVVMAALAAVD -KNKLKLEQKVTVSKEELIAASPLRDEHPDGNISLKELMHHAIVDNDGTANDVLLRLLGGP -TAVMQYLAQLEIQDIKVLNTDKEMAKSWNMQYRNTGTPKAMIKLLQALQQGKALSPKARE -LLLKWMTDAETGAARIKALLPAGTAVAHKAGSSATAAHNDVGIVTLPNGHHMVVAVFLTD -SKAPHASRDLTIAKITKLGWDAw ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Microcoleaceae bacterium UBA10368 TaxID=2055793 RepID=A0A355CJJ6_9CYAN ----LKTQIQILATENNLTAGIFLVDLDNGSYL-NLNGDATFASASTIKLPILVAFFQAVD -EGKVHLDQMLTLGAEHIVGGSGEMQDSPGRKYSALEVARKMIVVSDNTATNMMIELLGGA -EVLNQHFATWGLSATVLRNKLPDLEGT------NTTSPKDLINVMAQVDRGNLVSVKSRD -RILQIMRQTQN-DTLLPKGLGEGATIAHKTGNINT-MLADAGMVDLPNNKRYVVAVMVKH -SPETEKAAGSLIRDISRMSYRY- ->[subseq from] serine hydrolase n=1 Tax=Dolichospermum planctonicum TaxID=136072 RepID=UPI0014432547 ----LKNTLQSLAANSDLTPGVFLLDLDNGAYV-DINGNTSFPAASTIKIPILIAFFQDVD -AGKIPLDEILTLEKEMIVGGSGNMQYAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ -EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSARELGNLISMVNQGNVVTMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-LLADAGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSSAYQYf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Novosphingobium TaxID=2644732 RepID=A0A0N1AJW0_9SPHN ---AIQQRVASIAAAARGRVGVAAMDLDGGGQV-LINGDMPFPMASTAKVAVSATFLQMVE -QGRFRLDQPLPMMMPVPEARNLVAMVRPGPVYTAQTLIEKSITRSDNHATDGLIAAVGGI -GAVNRFLTQTGISGQHLDHTMATLVRARAIDTGTSSTPRAMIALLSAIDRGGALGPQARA -VLLDTMTRTSTGRNRIRAGLPEGVLLAHKTGTLA-GVTDDVGIVRMPDGRHLAMAIFVAG -PE-NHTAQAGMIARIASALYTGf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. URHD0057 TaxID=1380389 RepID=UPI00068779C1 ------------------------------------------------------------- -------------------------------GVSARSLMKRMLIHSDNRATDILLKDLGGP -SALHDWLQQSGVNGLRVDRTIAQLLSAKRWDRRDSSTPTAMVDLLRRIYRAELIRPKSRD -YLLDLMAQCETGKNRMKALLP-GVPIEHKTGTLD-GLTDDVGFISMPDGHRVAVAIFTRG -GS----DRPRAIAQAARAIYDGf ->[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-16 TaxID=2013662 RepID=A0A2N3DEN8_9PROT ---ALTASIDALTREFGGVVGVSVRSLDWGWQV-DANGNRPLPQQSVSKLWVAMTVLDARD -KGRLTLDDPVTLTRENLTLHQPIAALVVRDGTTVRELLLRAMQSSDNTANDRLMLLVGGP -EAVRAFIRDRGLDGIRFGPGERLLQASYIADPPDGATTSGMAMALARLKAGELLSPGSSN -FLINVMQGARTGRARIKAGTPADWKWGHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD -TSRPVPARQQLMQAVVASVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Cyanobacterium aponinum (strain PCC 10605) TaxID=755178 RepID=K9Z2J0_CYAAP ---ALRSKFDTLRAKYQLEPGAFFVDLDNGAYV-NYNGIAPFPAASTIKIPVLVAFLQDID -EGKIYLDEKLTMTEANRVPHSGNMQYQPGTQFTALYTATEMIINSDNTATEMIIERLGGK -DELNKRFQEWGLENTVIRNLLPDLEGT------NTTSPRDLGILLAKVNQGDLLSVRSRD -RLLEIMRRTKT-QTLLPQGLENNAIIAHKTGDIGT-VLGDAGIIDMPTGKRYIGAVLVKR -PHND-YSARTLIQEISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Dolichospermum compactum NIES-806 TaxID=1973481 RepID=A0A1Z4V313_9CYAN --------------NADLMPGVFLLDLDNGNYV-DINTNTSFAAASTIKIPILIAFFQDVD -AGKIRLDEMLTMQKEMIVGGSGNMQYTPGSKYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides plebeius TaxID=310297 RepID=A0A414X613_9BACE --qELYTNIYQFISQQKAEVGVAIIA-DGKDTV-TIENNRRYPLMSVFKLHQALAVGDYCK -RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AVTDRYIRSLGINDFSIQYTEDDMHQDLNLGYENWSTPLATAEVIEALLTRTLFDKPHQE -FIKEALVTCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacterium aponinum IPPAS B-1201 TaxID=2047986 RepID=A0A2G3PBP3_9CHRO ---ALRSKFDTLRAKYQLEPGAFFVDLDNGAYV-NYNGIAPFPAASTIKIPVLVAFLQDID -EGKIYLDEKLTMTEANRVPHSGNMQYQPGTQFTALYTATEMIINSDNTATEMIIERLGGK -DELNKRFQEWGLENTVIRNLLPDLEGT------NTTSPRDLGILLAKVNQGDLLSVRSRD -RLLEIMRRTKT-QTLLPQGLENNAIIAHKTGDIGT-VLGDAGIIDMPTGKRYIGAVLVKR -PHND-YSARTLIQEISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. AE3 TaxID=2594473 RepID=A0A516IQS1_9SPHN ------------------------------------------------------------- -------------------------------GVSAARLMDAMMTRSDNHATDLLLRDLGGP -ATVQAWLRQQGLEGLRIDRNIARLLADKRSDIRDSSTPRAMVDLLKRIDQATLLSRSNSD -YLLDMMARCRTGKNRIRALLPSGTPVQNKTGTLNR-YSSDVGFITLPDGRRLAVAFFARN -TN----NGPSTIAWAARTVYDGf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. PP-CC-3G-468 TaxID=2135656 RepID=A0A4R1U727_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVHSDNQATDQLLAALGGP -VAIQQWLSSHRITGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLAAQSRQ -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas aquatilis TaxID=93063 RepID=A0A511Q662_9SPHN ---RLTAAIDSLARNFDGKFGIAIRAVDDGWTVtSPGARTRMPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRDQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -SAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALARLARGELFTETSTR -ILLDTMGASVTGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQAVAAAVAN-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI0013717C30 --eQLEAELRTIGESFAGEVGIAVSEAESLATM-SYAGKKPFPQQSVSKLWVTLTALDLVD -EGALELAEPVTIRREDLTVYQPIREIVKARGTDYGELIQRAITQSDNTANDRLLRRVGGP -QAVEAFMRRNQITGVQFGTDERTKQSTYLADPMDGASARGMSKALARLARGDLLSESSTE -LILSTMEETRSGPRRLKGGVPGGWTFGHKTGTGQQSGYNDVGILTAPDGTHYSLVVLIGQ -TRVSYAERMAMMQEVTRAVVRH- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium EhC05 TaxID=1849171 RepID=A0A1B6Z7Q7_9SPHN ---ALERELAEIWRTFPGKTGIAVKRIDGNWEI-GHRQNEWFPQQSVSKLWVAMTLLDKVD -RGRASLSDAIRIGKEDLTLHQPMAVEVEREGKSVYTLLDKALASSDNTANDALLRHAGGP -EAVRNFIDKNDLQKIRFGPGERLLQSAYLADPIDGASPLAIVRALSKLARGELLSENSTR -LLQSILTRTRSGPNRLKAGVPAGWKFLHKTGTGQATGYNDVGIMTAPDGTRYAVAVMLGD -TTASVLQRMRMMQAVTRAIG--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0N7GSY1_SPHMC ----LSDRINGLWRAFPGKTGIAIQRIDGEWEF-SERGGDLFPQQSVSKLWVTMAVLDAVD -QGRLRLDQMVRIGPDDLAVHQPLAARVLAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -DAVRRFIANKGLGSIRFGPGERLLQSNYLANPVDGASPSAIASALTRLARGTLLSPESTE -YLLGVMSRTKSGPRRLKGGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN -TTSPIPARMSLMQAVSGAVAE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas crusticola TaxID=1697973 RepID=UPI000E2249B5 ---TLAEQLATIAAGGNGRIGIAATDLDTGESF-TYAARDPFPMASTVKVAIAATYLAGVD -RRRFDLDQLYR---------------RGGTVLTARRLIELMLIRSDNGAADILLQAVGGT -QAVNNWLNRAGIRGQRMDRTIARLVLAFVGDARDTSTPTAMVGLLAKLHQGVLLSPDSTR -YLFEVMGRCVTGPHRIKGMLPAGTPVAHKTGTLA-GVSDDVGIVSLPNGHRLALAIFAKG -MR-SEWERDRSIAQLARLLYDRf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Myroides marinus TaxID=703342 RepID=UPI0007421CBA -hqELNNKIKSVISNKNATVGVAIIY-DAKDTL-TVNNDHKYPTMSVYKFFQALNILDYMD -KHNISLDTEIYIKKEDLKEYSPLRDKSPKGEMSLRELIQYTASHSDNNISNLFFRSLIGP -KMTDLYFRSLGIHNFEIVSSEETMSLDFSNQYQNWITPLEATRILEMFRKEELLSPDYNN -FLRQAMIDTKSGQDKVKALLPKNTVVVHKTGMSFRAADNDLAIVYLPNGKQFSIAVFIMN -SKESDKTNASIIAEISKLAYDYf ->[subseq from] serine hydrolase n=1 Tax=Halothece sp. (strain PCC 7418) TaxID=65093 RepID=UPI0012372B4B ---ALKETFKRLAREKQLKPGAFIVDLESGQYV-SLQGESQFSAASMIKVPVLIAFFKAWD -EGRLELDEPLTMTEEVKAGGSGNMQEAVGKQYRALETAAKMISISDNTATNMLIQRLGGK -ETLNELFAAWGLEKTRIRNPLPDLDGT------NTTSPKELVKLLARLNNGELVSARSRD -YILQIMRTTRT-RTLLPQGLDKNATIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER -PHND-RNANELIRRYSRAAYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=A0A2W5C389_9SPHN ---ALVAAVNELARGFDGKLGIAVRSIDQDWQV-ATNGDIALPQQSVSKLWVAMTVLDAAD -QGRLRLDDPVRVTREDLTLHQPIAAMVRGDGATVGELLQRSLTQSDNTANDRLLRLVGGP -EAVRGFIRRKGLGTIKFGPGERLLQSAYVADPPDGAAPVAVTAALAKLKRGAILSAPSTR -YLIDTMESAKTGKQRLAGAVPPGWRFGHKTGTGQTAGYNDVGILSAPDGRSYAIAVMIGD -TPRPVRERQALMHAVIASVI--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A097EI50_9SPHN ---QLTSAIDALARNFDGKFGIAIRAVDAGWTVtSPGARIRLPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -AAVHAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFTETSTR -ILLDTMGASVTGRARLRAALPAGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQSVAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520DNB5_SPHSX ---QLTGAIDTLARDFDGKFGIAIRAVDEGWTVtSPGARTRLPQQSVSKLWVAMTLMDLRD -QGKARLDDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTYVGGP -AAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADALSRLARGELFTETSTR -ILLDTMGASVTGRARLRAALPTGWQIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIQERQRLIQSVAAAVAS-- ->[subseq from] Class A beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZT1_9BACT --aELEQALRTLAEGKRAETGIAVI-LNGTDTV-TVNDAGRYPMMSVFKFHQALAVADFLD -RNSLPLSTPLPIRESDLLPYSPLRDAYPQGGMSIGELLVYTLQLSDNNACDLLFRYIGGT -TAADRYIRTLGIEGFAVEATEEEMHRDMAACYRNWSHPLDAARLLEMLITRPLFRDASQE -FIIRTMTGCRTGQERLPKPLATGAVIGHKTGSGDRHGTNDIGFVQLPDGRHYTIAVFIRD -SQESLQETERIIAEASGIVYRY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium CG_4_10_14_3_um_filter_58_15 TaxID=1974093 RepID=A0A2M7LG03_9SPHN ---ALVREIEALWRTFPGTTGIAVKRIDGAWEF-GFRSDEYFPQQSVSKLWVAMTLLDKID -QGQASLSDPIRIGKEDLTVHQPMAVEVERNGKTVYTLLEMALASSDNTANDALLRHAGGP -DAVRRFIAKNSLGKIRFGPGERLLQSAYLADPVDGASPMAIAHALDKLARGQLLSDNSTK -LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQSTGYNDIGIMTAPDGTRYAVVVMLGD -TTASIPERMRLMQAVTRAVGR-- ->[subseq from] Beta-lactamase n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SIJ0_9BACT -------------------VGVAVM-TGRNKIL-LHNNKMNYPLLSVFKFHVALAVLDKMN -KQGTPLDHIVHVKASQLQPYSPLRQKYPNQDISLGELLRYSISLSDNNACDILIEYAGGI -GHIHQYINKLGICNFNLSETEDSMHRNPSKTYLNWSTPAEMVRLLEIADEKELFDPIYRD -FLWNTMIATSTGSNKLKGLLPSNVIVGHKTGSSDRNADNDAGVVIMPDGKKYYIAVFVMN -SRETDDENAAIIARISRMVYDEy ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter caeni TaxID=288992 RepID=A0A1M4V334_9SPHI ---QLQERIKHIIDTAGGKIGVGVKGMDFKGGF-VINGNHGYPMMSVFKFPLAFAILDKVD -KGELKLSQKFHMPKETLDTWSPMVKDFPNQDMTLADLLTYTVSKSDNNACDFLYTKVGGP -AAVNQYLHNAGVKGISIVYTEGEMEKDWALQYKNWCKPAASLQLLQLLYHQKLLSKSSND -FLIQIMRELPDWGKRITVLLPPTTELIHKTGASGMAAFNDIGIVTLPNGKHIAISVFASD -FKAPKERGINVIAAISKEIWDYy ->[subseq from] class A beta-lactamase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013CD078F -------NLAALEREYGARLGVFAVDTGTGATV-VHRADERFALCSTFKTLAAAAVLDRRP ---GARLDERISYGTADLVPYSPVTEKHTGQGMTLRELCDAAVRYSDNTAGNLLLRDIGGP -RGLTAYARRLGDRVTRLDHTEPELNSNPPGDPRDTTTPRAIA------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Kamptonema TaxID=1501433 RepID=UPI0002EAC056 ----LKAEIDKLAAQNNFTPGVFIVDLDTGGYA-SVSSDAAFAAASTIKVPILVAFFQAVD -EGRVRLDQVLTLRPEHIASGSGELQDSPGTKYTALEVATKMIAISDNTATNMLIELLGGA -EALNQQFQTWGLTVTAIRNNLPDLAGT------NTTSPKELVNLIGQINQGGLVSLRSRD -RLLYIMRQTQN-DSLLPRGLGEGAIIAHKTGNINS-LVADAGMVDMPSGKRYLVAVMVKY -AK-NEKGADKLIRDISRTTYEYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingopyxis macrogoltabida TaxID=33050 RepID=A0A0P0D6Q1_SPHMC ----LSDRINGLWRAFPGKTGIAIQRIDGEWEF-SERGGDLFPQQSVSKLWVTMAVLDAVD -QGRLRLDQMVRIGPDDLAVHQPLAARVLAEGMSVRDLIETAITHSDNLANDSLLRTVGGP -DAVRRFIANKGLGSIRFGPGERLLQSNYLANPVDGASPSAIASALTRLARGTLLSPESTE -YLLGVMSRTKSGPRRLKGGLPPGWQFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVMLGN -TTSPIPARMSLMQAVSGAVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=A0A4V2FM90_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -VAIQRWLSSQNIPGIRMDRSIAQLLRGHLADIKDVATPIAMVTLLNKLDNGTVLAPQSRA -FLLGLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVARVIYNRf ->[subseq from] Beta-lactamase class A n=1 Tax=Bhargavaea ginsengi TaxID=426757 RepID=A0A1H6UBS8_9BACL ---QLQEKVERILEGTDATFGVSIKHLQSGEEV-RIRADEPFQMASVFKVPIVLTLFEQVH -EGQIDLTTRIALTEEDRVPGSGILQELDPGLVTIKDLATLMTIVSDNMATDVLLGML-GK -DAVGDTMRRLGAENISIVHSCWELLSMRKDQENNVCTPDTMTGLLVKLAEGAFINPAVSE -AVLDILYRQQL-NDRIPARLPSGTRVAHKTGTIAS-AVNDSGIIELPGGGPLIISIFSAG -NE-TTQGGEAMIARIAEAAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A524A9M6_9ARCH ----LLDKISGVEKGFGGTLGVAVKYLGSGESA-SMNGDELFPTASVFKIPVIVEFYRQLE -SGAVSLDEKITLMDGDKVPGSGILKELSEGLISYSDLLELMIVLSDNTATDLVVERV-GK -ERVNATLRELGLEKTLVVADCRDILFSLGVEENDVTTPDEMLRLLEMIVDGEAASRESCD -AILEIMGKCQTGIYRISKYLPEEIEFAHKTGSLP-GVRNDVGIVTHKTGQRYIICCFTKD -AE-DVYSAEEVIARVSEVAYDYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. SYSUP0001 TaxID=2303576 RepID=UPI000E56F659 ------------------------------------------------------------- --------------------------------RSARALMEAMMIKSDNVATDLLLANLGGP -AKLQQWLRERHVSGMRVDRTIAQLLAAKRWDVRDSATPRAMVELLRRIDKGELLRPSSRA -YLLDLMARCKTGRNRMRALLPASAQVQHKTGTLNN-YTSDVGFITLPDGRRLAVAFFARG -GA----NRPATIAMAARTIYDGf ->[subseq from] Uncharacterized protein n=2 Tax=Mastigocoleus TaxID=996924 RepID=A0A0V7ZMD9_9CYAN ----LKASLQSMANQNSIRPGVYLIDLDDGRYV-NVNATLSFPAASTIKIPILVAFFQDVD -NGKIRLNEVLTMEKDDMVGGSGDMRNQPAGTYKALEVADKMMTISDNTATNMLIKRMGGM -QALNQRFRRWGLTHTALRNPLPDIEGT------NTTSPKDLGDVMAMVSRGRLVSMQSRD -RILAIMRQNTR-RHLLPTGLGEGATIANKTGYIGK-MLGDAGLVDLVTGKRYTIAVMVER -KVKDDPSAEKFIKSASRQAFE-- ->[subseq from] Beta-lactamase n=2 Tax=Phenylobacterium zucineum TaxID=284016 RepID=B4RBD1_PHEZH --kALQDELSALALAYGEEVGIAVTDLDQGWTA-GVDPDGVYPQQSVSKLWVAIAVLKAAD -EGRLELDRTVLLTDADRSVFQPVAYNIGPQGTTIEALLRRAIVQSDNAANDRLMREVGGP -EAVAEALDGLGLKGVTVGAYERDLQAAYLAEPMDGAQPAAIARALAALKKGELLSPASTD -RLLTLMEEVRTGPRRLKGGLPPGWSIGHKTGTGQRGGINDVGLLTAPDGRIYAVAVMMRR -TWKPVPQRLAFMQAVSRAVAAEw ->[subseq from] Beta-lactamase class A n=2 Tax=Dactylococcopsis salina TaxID=292566 RepID=K9YPP7_DACSA ---TLKQTLQRLGSQSQLNPGAFIVDLDSGEYV-SLQGEKAFSAASMIKVPILIAFFHAWD -EGKLKLDERLTMTEEVKAGGSGNMQEAVGTEYLALETAAKMIIISDNTATNMIIKRLGGK -EALNQLFAEWGLEQTRLRNPLPDLEGT------NTTSPKELVELLAKLNQGKLVSARSRD -PIFRIMRETKT-RTLLPQGLGEGASIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER -PHND-RAANELIRQFSRETYQYf ->[subseq from] Beta-lactamase class A n=2 Tax=Oscillatoria acuminata TaxID=118323 RepID=K9TTS6_9CYAN ---TLKEKLQAMAAEHELTPGVYAIELDTGAYL-DLNGSQRFSAASTIKVPILIAFFQDVD -AGKITLNEMLTMKEEHIAEGSGDMQTEPGTKYSALETATKMSQISDNTATNMLIERLGGA -AALNQRFASWGLSNTAIANPLPDLAGT------NTTSPQDLVQVMGLVERGQVLSLRSRD -RLLKIMQGTVN-NSLLPQGLGSGAAIAHKTGDIGT-AISDAGLVDMPNGKRYLMAAIVKR -PHND-PEAEELIRQMSQVVYQSf ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A525HIC8_SPHSX ----LVALVQSLTRDFGGKVGIAVKSLDDDWMA-TSNGDLKLPQQSVSKLWVAMTVLDARD -QGKLTLDDPITVRREDLTLHQPIAALVKDAGTTVGELLQRALTQSDNTANDRLLQFVGGP -TAVRAFLAKKAIADIRFGPGERALQSRYIADPVDGAAPRAIATALARLKRGELLSPSSTQ -YLIGTMESSRTGKQRMRGAVPEGWTFGHKTGTGQTAGYNDVGFLIAPNGKAFTIAVMIGD -TDKTIAERQALMQAVVLGVVT-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WN54_9BACT ---ELTKQIAALCNDSQGEIGVTVIHVESGRTV-NFEGEKKLPLYSVFKLPLALEVLKRVA -EKKISLDQKIHVAPADVAPGSQFNADLWRKPKTVAELLEFSIVRSDNTSSDQLLQLVGGP -AVVTERMRTLGFPNIDIVSTVREYATS--QGKPNLATTANLARLLSRLQKGELLEPSHLS -LLLGFMERARTGERRLRASLPLGTTVAEKTGSGAD-STNDVGLITLPDGGHLAMAVLIHN -SKLTAEAQERLIADLARKAYDAf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D8C1BC ----WQQAVEDVLKEAPGIFGIAAMHLETGETA-GHLDEELFQLASAFKIPIMVTMMREVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEEKGMIGITALSR -GVIDKEAAELTIARVAKAIYE-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A249MSG3_9SPHN ------SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRLADTTTITRNDLTLHQPTAAMVGTKGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya valderiana BDU 20041 TaxID=322866 RepID=A0A166T6X0_9CYAN ---ALKERLQQVAAEYGLTPGVAIVDVATGDYV-RLSDTMSFSAASTIKVPILVAFFRAVD -AGTVRLDEVLTMEESHIAGGSGYMQYAPGTRYSVLEVASSMIIDSDNTATNMLVDRLGGA -KVLNEQFREWGLTETTIRNPLPDLEGT------NTTTPQELAKLLGQLERGELVSMRSRD -RMMRIMSQTAN-DALLPQGLGEGAFVAHKTGNLRS-VLADAGAIDLPNGKRYLMVAIVKR -PDED-DRAADLIRQMSATAYDYf ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingobium TaxID=165695 RepID=A0A560XEG7_9SPHN ------SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRLADTTTITRNDLTLHQPTAAMVGTKGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Anabaena variabilis TaxID=264691 RepID=UPI000F8DEDF3 -----KTAVQNLATASNLTPGVFMVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD -AGKIRLDEMLTLQQDMIAGGSGTLKSNPGTQYSALEIATKMITISDNTATNMLISRLGGK -DVLNERFRTWGLATTMIRNSLPDLQGT------NTTSPRELGNLISMINQGNIVSMRSRD -LMLNIMSRTER-DHLLPSGLGQGSKAYHKTGDIAT-MLADAGLIDIPSGKRYIAAVMVQR -PTND-PRAEKLISSISAAAYQHf ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. B2 TaxID=2583228 RepID=UPI0011A4A3C0 ------SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRLADTTTITRNDLTLHQPTAAMVGTKGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVAKAVAA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI12_KLEPN ------------------------------------------------------------- -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGHETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDY------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Candidatus Latescibacteria bacterium TaxID=2053570 RepID=A0A3N5WVJ1_9BACT ----VEAEIERIAAEVPGEVGVAAIHLETRRLL-SHNGTDRFPMASVYKVPIAVQALSRVE -AGDLDLEKTLPILPEDHRPGSGHIAEFRSPGLSLRNLLRLSLIKSDNTASDLVLRFAGGP -KAVTKRIRSLGIVDMRVDRSTLQMILIASVDVRDTSTPIAMARLLEKIWSGEALGEEARD -FLLGTMAECN-GSRRLKGMLPPGLEPAHKTGTMGYSTVNDAGIIELPDGGHLAIAVFINQ -AEEDVFELENVIAQITRLLVDFf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. EC-HK361 TaxID=2038397 RepID=A0A5E7XRR7_9SPHN --qQLADRVSNLIRAFGGKAGVGIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDQRD -RGLVRMDDPIVVRTQDLTLHQPIAALVKGDGTTVGELMRRALTMSDNTANDRLLSLVGGP -MAVREMIAAKQLGDIRFGPGERLLQSRYVADPIDGAAPLAIADALARLARGELLSETSTR -LLLDTMAASHTGRARLRAVVPTDWQIAHKTGTGQNAGLNDVGLLTAPDGRRYAVAVMIGD -TTHTMRERQQLIQAVGAALI--- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc punctiforme NIES-2108 TaxID=1356359 RepID=A0A367RM87_NOSPU --kALEPQIKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYDY- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf10 TaxID=1735676 RepID=A0A0Q4CZR5_9SPHN ----LVSAINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGKLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTN -WLLDTMSHTRTGRARLRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TARPVPERQQLIQTVVSAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Coxiella burnetii TaxID=777 RepID=UPI000D409346 ---SINKKLAALEKTTGGRIGLYAIDTENNVRF-QYRARERFPFCSTAKVIVVSAILKKSI -TDPHFLQQNVVYKKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFPQLI -QLQTWLK----------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Trichormus variabilis SAG 1403-4b TaxID=447716 RepID=A0A433USU6_ANAVA -----KTAVQNLATASNLTPGVFMVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD -AGKIRLDEMLTLQQDMIAGGSGTLKSNPGTQYSALEIATKMITISDNTATNMLISRLGGK -DVLNERFRTWGLATTMIRNSLPDLQGT------NTTSPRELGNLISMINQGNIVSMRSRD -LMLNIMSRTER-DHLLPSGLGQGSKAYHKTGDIAT-MLADAGLIDIPSGKRYIAAVMVQR -PTND-PRAEKLISSISAAAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517I1E7_BREBE ----WQQAVENVLKEAPGIFGIAAVHLETGESA-GHLDEELFQLASAFKIPIMVTLMREVE -AGRIRLDQRVTLKWEGRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQIIELIGGI -DKVNEHMHELGLSQIHLRHNCWELLNSMPTRDNNVATPAELNRLLIMIARKEILTEASCE -LMLDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDKEAAELTIARVAKAIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. EO9 TaxID=2304063 RepID=A0A418YSL0_9SPHN ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID -AGALTLDDRLA---------------SPAGPVSVATLVDLMLTRSDNDATDLLVARAGGP -AAVHHWVAGLGIRGLRVDSNTADLLYAFAQDPRDTATPTAMTDLVAAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVITLPDGRLFAITVFVMQ -DHKGQATRDRIMAEAARATYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium quisquiliarum P25 TaxID=1329909 RepID=T0GYZ5_9SPHN ------SVIRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLTDTTTITRKDLTLHQPTAALVGSSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRAFLARRTIKDIRFGPGERLLQSNYLANPPDGAAPSSIVKALAKLKEGEMLSPASSQ -LLMSIMSQAKTGPQRIKGGVPAGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis wesenbergii Mw_QC_S_20081001_S30D TaxID=2486245 RepID=A0A552J9C0_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_20CM_2_65_9 TaxID=1803428 RepID=A0A1Q8AJ58_9BACT ---RLRTHITQAMTEARGRMGVAIKHLESGTEI-VVNADEKFPMASTFKLPVLVTLYDRAK -KGQVKWDETVDVGVHDQHLGSGDLYDVPGVKLSLHNVANLMMMVSDNSGADICLTRA-GA -DNVNALMSSLGAGDIHVDRPTQELILKFAADARDQATPKAFVTLLEKMWRGEAVDQASSE -AMLETMKRCRTGAGRIKGLLPSNTTVAHKTGTIG-GVVDDVGIIYLPEEGHVAIAVLSKQ -TRATDVEVERAIAQIARYAYAYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A649UHI5_ACIBA ---ETLVKVKDAEDQLYARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTT------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Apibacter sp. wkB309 TaxID=1679467 RepID=A0A2S8A6K7_9FLAO --qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -KNLLSLESNIYLKKSDIKKYSPLAKEHPEGNIPIGDLLNYTVSKSDNNASDALYYYMNGT -KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD -FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARMIADISQVVYNFy ->[subseq from] Serine hydrolase n=1 Tax=Aphanothece hegewaldii CCALA 016 TaxID=2107694 RepID=A0A2T1LSQ1_9CHRO ----LKQKIEKIAAKYKLQLGTFVVDLDNGAYV-NLSGDSIFAAASTIKIPILVAFLQDVD -AKKIYLDESLVMDKNVIATGSGNMQYKPDQKFTALETATKMITISDNTATNMIIRRLGGK -EVLNQRFLEWGLQQTVINNILPDLEGT------NTTSSKDLVYILNRVNQGDLLSIKMRD -RLIEIMQGTMT-KTLLPAGLEKSAMIAHKTGDIGT-TLGDAGIIDMPNGKRYLMSIMVKR -PHND-ENGRKLIQEVSRVVYQH- ->[subseq from] Beta-lactamase n=1 Tax=Alkaliphilus oremlandii (strain OhILAs) TaxID=350688 RepID=A8MEZ1_ALKOO ----LENKIKGFLRDIDGNVAVVIKNFNNGEII-QINQDYIFPSASTIKLVIMSELLKQVK -ENKLSINETIVITDKMITGGDGILKENVGHRFTLGEIMTLMIIISDNTATNLLIDIV-GM -DNVNRMAQELGLKRTKLQRKMMDSVAV-KYGRENYTSAQDMLNILELTYKGENIDGYYSK -MMLDILKRQQV-GGRLNLYLPENTVIAHKTGDLDR-LEHDVGIVYLPNCE-YIICVLTNE -TK-SNKDGRQIIGNISKLVYDQy ->[subseq from] Uncharacterized protein n=1 Tax=Barnesiella intestinihominis YIT 11860 TaxID=742726 RepID=K0X250_9BACT ---TVGQKIRQAIQGKNATVGVAFSI--DGQLF-TFNDEHRYPLMSVFKLHVAIAALQKME -NECIALDSLRFIESSQIHKYSPLRELYPERNLSYADLMRYAVSQSDNNACDILIDYLGGI -DIVKDRIDKLGITNYNLTETEETMHSRISNCYNNWSTPSSTLQLLEKLYNEPILNETHTE -FLKNILIETSTGKDKIKAGLPDNIVLGHKTGSSDKIGDNDTGVIYLPNGKLCFLAIFIKD -SRESDQTNAQIIADIARIIYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E7NGH4_9BACT ---RLRGALLAIAQRFPGDVGVYVHHIESGMET-GIDEDTPYGMASTYKVPILVELMTRVE -AGDLSLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA -DQITAQMRSLGFQNIRVDRTTLELILDFYGGDKDKASARDMTELLVMISEGTAVSRGSSE -VIMEILARTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGDGRFAISVFTLA -NEADTELGEHTIAEIARTAYDFf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2E9CSR3_9SPHN ------SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRLADTTTITRNDLTLHQPTAA-MVGTNTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPAAIVQALARLKQGDMLSSASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Alkaliphilus oremlandii TaxID=461876 RepID=UPI00059FD1CC ----LENKIKGFLRDIDGNVAVVIKNFNNGEII-QINQDYIFPSASTIKLVIMSELLKQVK -ENKLSINETIVITDKMITGGDGILKENVGHRFTLGEIMTLMIIISDNTATNLLIDIV-GM -DNVNRMAQELGLKRTKLQRKMMDSVAV-KYGRENYTSAQDMLNILELTYKGENIDGYYSK -MMLDILKRQQV-GGRLNLYLPENTVIAHKTGDLDR-LEHDVGIVYLPNCE-YIICVLTNE -TK-SNKDGRQIIGNISKLVYDQy ->[subseq from] Beta-lactamase n=1 Tax=Nostoc azollae (strain 0708) TaxID=551115 RepID=D7DW46_NOSA0 ------TTVQNLARPYNLIPGVFMVDLDTGAYV-DINSNASFPAASTIKIPILITFFQDVD -AGKIRLDEMLTLQKEMISEGSGSLRQAVGSQYTALDIATKMITISDNTATNMLVTRLGGQ -EVLNERFRSWGLATTMIRNPLPDLQGT------NTISPRELGDLIAKVNQGNLVSMRSRD -LMLDIMRRTER-DNLLPSGLGQGARAYHKTGDIGS-MLGDAGLIDIPTGKRYIAAVMVQR -PNND-PSAEKLISSISSAAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis TaxID=329854 RepID=A0A412YFL9_9BACE --qKIEQQIDSFLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI -DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFATQYKD -FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. URHD0057 TaxID=1380389 RepID=UPI00048B382C ----IRDRVEELGRAFDGRVGIAVRAVDDNWAT-GWKADEFYPQQSVSKLWVSITAMDAVD -QGRVRLDDKVTLTRSDLTVHQPIRSLILEGGTTLADLMVKAITTSDNTANDKLMRSVGGP -TAVREMIHGKHLGAIRFYDGERALQSRYVDDPYDGAAPSAIAAALARLKRNELLSPASTA -RLLDIMSHTKTGANRLKGGLQPGWVLNHKTGTGQQAGYNDIGILTAPDGRSYSVAVMIKL -TKVPLPTRMALMNNVVRAVIAQ- ->[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A537M8T2_9PROT ----LEAQVKALGQSFRGDIGIAVQEVDSGWST-AYDGNTFFPQQSVSKFWVALTALDKAD -RGELSLFAPVTMHKEDITLHQPIAAEIGPNGTSVAELMTRALQQSDNTCNDFVLWRAGGP -DAVRNFLRSKGISGIRFGPGERKLQSNYIANPMDGATPLGIVDALARLKRGELLSPASTE -RLLGIMSHTKTGPQRLKGGLQPGWTLSHKTGTGQQAGYNDIGVVTSPDGRSYAMAVMIRR -TSAPLQERMAAMQATVRSVI--- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas pruni TaxID=40683 RepID=UPI000831797E -----TALVPSLTRDFGGKVGIAVTSIDDGWTV-ASNGDLKLPQQSVSKLWVAMTVLDLRD -QGKLSLDDPYTVRKEDLTLHQPIAALVKGDGTTVGGLLQRALTQSDNTANDCLLRLAGGP -TVVRAFLAKKGIADIRFGPGERLLQSRYIADPPDGAAPRAIATALARLKKGELLSPVSTQ -YLMSTMESSHTGRQRLRGAVPEGWTFGHKTGTGQTAGYNDVGFLIAPNGKAYAIAVMIGD -TPKTIPQRQQLMQAVVTGVV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=A0A087NE09_9SPHN ---RLIAQFQRFATLTDGTVGITVRDLASGESL-SLNGDTLFPMASAYKVAVAGKIFAMID -AGQLALTDIVPR---------DVATMGPGAALPVAQLLDLMLTQSDNHATDMLVARAGGP -TAVNGWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGRALSPASTH -AFITIMERCRTGKTRLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ -DHRGRVMRDRIMAEAARAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. SCG-1 TaxID=2072936 RepID=A0A2L0AFC7_9SPHN ------SIIRSLGQNFNGKVGIAVRRVDADWTV-AWNGTDLFPQQSVSKLWVTMAMLDAVD -RGKLRLSDSVTIRREDLTLNQPLAAMVDSDGTTIEDLMTRAMAQSDNTANDMLLRKVGGP -EAVRSFLARRFVSNIRFGPGERILQSAYLANPPDGAAPSSVVMALAKLKRGEMLSPSSTS -LLLDVMHRAKTGPQRIKGGVPPGWSYLHKTGTGQATGFNDIGIMTAPDGTSYAVAVFIGS -TTVSIPERWQLMQSVARAIAA-- ->[subseq from] serine hydrolase n=1 Tax=Alphaproteobacteria TaxID=28211 RepID=UPI00082A2737 ---TFEQRIAELANPALGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATYMEMVE -QGRYTLTSEFPLMMPVASAKFSSAKAPVRAGMPAIDLIEIMITRSSNPATDALLAAVGGP -QAVNAFMARKGIAPFSINRDIATLVRATHIDSRDAATPRAMTRLLAGLYRGEYLSDQSRQ -VILGAMSRTVTGKRRIPANIPLEARVSHKTGSLSN-TSSDIGLIECPDGRVIAVAIYVTG -QGG-KAAREERIAAIARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Cuspidothrix issatschenkoi CHARLIE-1 TaxID=2052836 RepID=A0A2S6CZ58_9CYAN ------NSLQTLSSNSTLTAGIFLLDLDNGSYV-DINGNTSFAAASTIKIPILIAFFEDVD -AGKIRLDEKLTLEKEMIAGGSGNVQYPPGTKYTAIDMATKMITISDNTATNMIIAKLGGR -ESVNARFRSWGLTTTMIRNSLPDLEGT------NTTSPKELANLILMVNQGNVVSMRSRD -LILNIMGRTQR-DNLLPAGLGKGANAYHKTGDIGT-MLGDVGLVDVPTGKRYIAAIMVQR -PNND-PLAEKLINSISSTAYQHf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Bhargavaea cecembensis DSE10 TaxID=1235279 RepID=M7NHI5_9BACL ---KLQDKIEKLLKETDATFGISIRHLQSGEEV-RIRADESFQMASVFKVPILLALFEQVH -EGRIDLTTRIALTEEERVPGSGILQELDPGLVTVKDLATLMTIVSDNMAADVLLGML-GK -DAVRDTARRLGAGSISIAHSCWELLSMRKDRENNLCTPDDMTAILTNLAEGAFISPGLSE -SVLDILYRQQL-NDRIPARLPAGTKVAHKTGTIAS-AVNDAGIIDLPGGGPLIISIFSAG -NP-TTDSGEAIIARIAETAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas edaphi TaxID=2315689 RepID=A0A418Q229_9SPHN ------------------------------------------------------------- ---------------------------------SARSLMEAMMIHSSNQATDMLLRNLGGP -SMVQAWLTQQGVTGLRIDRNIAQLLAARRWDIRDSSTPRAMVQLLRRLDSGEMLRPQSKA -YLLDLMARCATGKNRIRGLLPSNVRVQHKTGTLNN-YTSDVGFLTLPDGRRLAVAMFARQ -GV----DRPGTIARAARAIVDGf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. LPB0140 TaxID=1913578 RepID=A0A1L3J9U4_9SPHN --qNLQQEIFDLWRVFPGKTGISVHSLDEGWTV-GQRLDDLFPQQSVSKLWVAMTILDQVD -RGKLRLDDEVVITRNDLAVYQPVRDKVLREGESVASLLERAITQSDNTANDSLLRTAGGP -EAVHDFIAKHQLGAIRFGPGERLLQSNYLADPIDGASPRAISLALAKLSRGKLLSYGSSS -YLLDLLNRVRSGPNRLKGGVPSGWSIGHKTGTGQSTGYNDVGILVAPDGRQYMVAVMLGD -TTASIPERMQLMQSVVRAIVR-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium algorifonticola TaxID=2008318 RepID=A0A437JA66_9SPHN ----LLSIIQSLGRGFNGQVGIAVRRVDADWTV-AWNGTALFPQQSVSKLWVAMTLLDAVD -RGKLSLSDSVTVRRDDMTLHQPLASLIGRDGTTLSSLMNRAMTQSDNTANDVVLRKVGGP -EAVRSFLARRFVGNVRFGPGERLLQSTYLANPPDGAAPSAVVMALAKLKRGEMLSPASTQ -LLLATMAQAKTGPQRIKGGVPAGWTYMHKTGTGQSTGYNDIGIMTAPDGTSYAVAVFIGS -TTEPIPKRWELMQSVARAVAEN- ->[subseq from] Beta-lactamase n=1 Tax=Halothece sp. (strain PCC 7418) TaxID=65093 RepID=K9YFE9_HALP7 ---ALKETFKRLAREKQLKPGAFIVDLESGQYV-SLQGESQFSAASMIKVPVLIAFFKAWD -EGRLELDEPLTMTEEVKAGGSGNMQEAVGKQYRALETAAKMISISDNTATNMLIQRLGGK -ETLNELFAAWGLEKTRIRNPLPDLDGT------NTTSPKELVKLLARLNNGELVSARSRD -YILQIMRTTRT-RTLLPQGLDKNATIAHKTGDIGS-LVGDVGIIDRPSGKRYLAAIMVER -PHND-RNANELIRRYSRAAYQYf ->[subseq from] Class A beta-lactamase n=3 Tax=Candidatus Gastranaerophilales TaxID=1906119 RepID=A0A292SSD7_9BACT ----------------NVNVGIATL--KDKDLV--VVNNKKYPLLSVFKYFVAIKVLKYID -QKHISLDTKITINQNDMQTHSPMIKDYKNYPITLAQLLEYMISQSDNNACDILIDYSGGI -NELEKFIHELGFNDIIIKVNEKDMNSDIYNQYLNTSTPKDIVLMMKRVKDNNILSSSSFA -FLENIMLKTSTGENKIKAGLPKNIKIYHKTGSGSRTADNDAGYVRLPNGDLYYIAIMIKD -SPLSDDENSKIISDISKIVYQYf ->[subseq from] class A beta-lactamase n=1 Tax=Bryobacter aggregatus TaxID=360054 RepID=UPI000563C606 ---TLQTKLDGLGKSIDGRVGICVRDADTTTCV---RGAERFSLQSVMKLVVGIAVLDAVD -HRGWKLEDPVLVRKQDLSLVQPISKLVGESGTTVGDLVRRAIVDSDSAAVDILIAKLGGI -EKVQAFLNRKKIAQVRLDRDERHLQTKYQKDPRDTATPLGMTQLLQDLALGKLVSKSSTA -FLMRVMEETVTFPDRLKAGLAPGWKLGHKTGSSSTVATNDVGVMTAPDGRQISVVVFVAD -SRATLKEKAVVMSGVSRAVCESy ->[subseq from] Beta-lactamase n=1 Tax=Microcoleus vaginatus FGP-2 TaxID=756067 RepID=F5UBJ4_9CYAN ----LKTQVQVLATENSLTAGIFLVDLDTGSYL-NFNGDTAVASASTIKVPILVAFFQAVD -EGKVQLDQMLTLKSEHIVGGSGEMQDAPGKKYSALEVAQNMIVVSDNTATNMMIELLGGA -EVLNQHFANWGLSTTVLRNNLPDLEGT------NTTSPKDLINIIAQVDRGNLVSVKSRD -RILQIMRQTQN-ASLLPKGLGEGSVIAHKTGNIDT-MLADAGMVDLPNGKRYLVAVMVKH -SPETEKPAQTLIREISRISYRY- ->[subseq from] Putative beta-lactamase n=1 Tax=Alistipes putredinis DSM 17216 TaxID=445970 RepID=B0MWK8_9BACT ---DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD -RNGLTPDTEIFIPEEELVPYSPLRKEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP -AATDRYVRSLGLRNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE -MIRQNLINCKTGADRLPKPLSTGAVIGHKTGTSDRDGTNDPGFVILPDGTRYTIAVFIKD -SAENPETNARIIADISETVYRY- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis viridis Mv_BB_P_19951000_S68D TaxID=2486270 RepID=A0A552HNP4_MICVR ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DAD078 ----LKSAIQSLAASNNLTPGVFLLDLDNSGYV-DLNGSASFAAASTIKIPILVAFFQDVD -AQKIRLDESLTMSKGMVAGGSGNMQKPVGTQFTALEVATKMMTISDNTATNMLIARLGGI -DALNQRFQSWGLTTTAIRNILPDLGGT------NTTSPKELGTLMAMVGKGNLVSMRSRD -RILDIMRRTVR-NHLLPAGLGPGATIAHKTGNIGT-ILGDAGLVDVPTGKRYVVAVMVQR -PRND-TDAEKLIVSISRVAYQQ- ->[subseq from] serine hydrolase n=1 Tax=Cyanobacterium aponinum TaxID=379064 RepID=UPI0012BB1710 ----LRGKFDTLRAKYQLEPGAFFVDLDNGAYV-NYNGIAPFPAASTIKIPVLVAFLQDID -EGKIYLDEKLTMTEANRVPHSGNMQYQPGTQFTALYTATEMIINSDNTATEMIIERLGGK -DELNKRFQEWGLENTVIRNLLPDLEGT------NTTSPRDLGILLAKVNQGDLLSVRSRD -RLLEIMRRTKT-QTLLPQGLENNAIIAHKTGDIGT-VLGDAGIIDMPTGKRYIGAVLVKR -PHND-YSARTLIQEISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. URHD0007 TaxID=1298856 RepID=A0A2U1FZ26_9SPHN ------------------------------------------------------------- ---------------------------------SARSLMARMLIHSDNRATDMLIRDLGGP -SAIHNWLRQNGVTGLRVDRNIAGLLAAKRWDSRDSSTPTAMVDFLRRIYRAELIKPESRN -YLLDLMAQCETGKNRMKSLLPNGTPVEHKTGTLT-GLTDDVGFITMPDGHRIAVAIFARG -GS----NRPRTIAEAARVIYDGf ->[subseq from] Serine hydrolase n=3 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A0Q4F9Y0_9SPHN ----LVSAINALGGGFQGKVSIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGKLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLTPQSTQ -WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TSRPVQERQQLIQTVVSSIV--- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. YH-07 TaxID=2182384 RepID=A0A345YI45_9SPHN --qELDREISRIGGTFAGHVGIAVHDIEALRTL-HFNGLERFPQQSVSKLWVAMTALDEVD -AGRLDLAEMVEIRSRDLTVYQPIRKIVRRKGSDYADLIARAIVESDNTANDRVLRRVGGP -EAVQDFLDGHGLSSIRFGTDERTKQSTYLADPPDGAPPVAIVEALARLYRGDLLSEESTR -LLLDTLEQTKSGPRRLKAGAPEGWTVRHKTGTGQQSGYNDVGIVTSPQGRGYAVAVMIAR -TREPTLTRMEMMQSIVQAIAKY- ->[subseq from] Uncharacterized protein n=1 Tax=Propionispora sp. 2/2-37 TaxID=1677858 RepID=A0A0K8JD24_9FIRM --eALRKKIEQMTAPYTGNWGILVKNINTGESL-SIEPDRVFPSASMIKLPIMFEVMRQAA -AGALSLDDTLLVTAAARVGGAGILHERPGIAMTIRELVTLMIIISDNTATNLLIDLV-GM -EAVNRTSTNLGLCSTFLRRHMMDFAAA-KAGNENETTAADMALMLEAVYQGRGLPQGYAD -IMLGILKRQQV-RDKLPFYLPEEFEIANKTGTLH-GVEHDAGILYFPDG-PYIVCVLTGN -LTAN-YEGIQLAAGIGKAIYEH- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=A0A0S3EX37_9SPHN ---RLLAQFQSFAVLTDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILSMVD -AGTLNLQDLLD-------------PPLPAKSRSVHDLIDLMLTHSDNDATDALVARAGGP -AAIDEWVGALGVKGLRVDSDTAHLLYAFTRDPRDTSTPRAMNALLANIQLGKALKPASTA -YLLDMMERCHTGKARLKAMLPPGTRIAHKTGSLN-GYGGDVGIVTLPDGRMFTISVFVMK -DYKGRETRDSIMAHAARAAYDYf ->[subseq from] Serine hydrolase n=3 Tax=Microcoleaceae TaxID=1892252 RepID=A0A3D5GCE9_9CYAN ---ALKTQIQVLATENNLTPGIFLVDLDTGSYL-NLNGDATFASASTIKLPILVAFFQAVD -EGKVHLDQMLTLGAEHIVGGSGEMQDSPGRKYSALEVARKMIVVSDNTATNMMIELLGGA -EVLNQHFATWGLSATVLRNKLPDLEGT------NTTSPKDLINVMAQVDRGNLVSVKSRD -RILQIMRQTQN-DTLLPKGLGEGATIAHKTGNINT-MLADAGMVDLPNNKRYVVAVMVKH -SPETEKAAGSLIRDISRMSYRY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9UW30_9BACT --qKLESTIRDVDSHLDGVMGVAIEDLTTGDHF-FLHENEVFAQASSIKITVLAQLYQQAQ -QGKLKLTDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -DNVNSMLDSLGLSHTRLRRKMMDLKAA-AEGRENISTPSEMMTLLEAIHHGKVLNKESTA -DFFKVLSTNKS--SWIPRDLPADLKIANKPGSLE-AVRNDSGIVFVEGH-PYVICVMTSF -LR-NERDGEDAISKISLAAWRMf ->[subseq from] Putative beta-lactamase n=1 Tax=Planktothrix sp. PCC 11201 TaxID=1729650 RepID=A0A1T4ZDZ9_9CYAN ----LKTAILGLAKDSKLKPGVFLVDLDTGKYV-DIQGQEALPAASTIKVPILVSFFQAVD -EGRLRLDEVLTMEAKHVAKGSGELQKPVGSKFTALETANLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPSGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLVGVLVER -EA-DDPQANELIRQISSTIYQYf ->[subseq from] Beta-lactamase n=1 Tax=Richelia intracellularis HH01 TaxID=1165094 RepID=M1WZ40_9NOST -----------LANNTKLTPGIFLVDLDNGNYV-DFNAANSFPAASTIKMHILVAFFQDID -NGKIRLYEQLTMEKGLIVGGSGNMGQKPGTKFTALEVATRMMTTSDNTATNMLIKRMGGI -DVLNQRFRSWGLSITTINNLLPDLKGT------NITSPKELGELMAMVSKGNLVTMRSRD -RIMDIMRRNTR-NNLLPAGLPKGATIAHKTGDIGS-MLADAGLIDLPTGKRYLAVVMVQR -PYND-PSAETLIKSVSRIACQQf ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI000A3D187E ----FEQRIRELANPAEGRIGVAAIDLATGEEI-MVLGDQLFPMASTSKVAVAATYMSMVE -QGRFSLTSEFPLMLPVRSASSPKAPVRAGQTMQAIDLIEIMITRSSNPATDALLAAVGGP -DVVNNWVRRQGIGEFSINRDIATLVRVTHIDSRDAATPRAMVRLLAGLYRGEFLSDESRR -VILGAMSRTVTGKNRIPAYIPLEARVSHKTGSLFN-TSSDIGLIECPDGRVIAVAIYVTG -QG-TKLARQDRIAAIARALYDGf ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11162 TaxID=2055781 RepID=A0A355DVM7_9CYAN ----LKSQIQALTAQNKLQPGIFLVDLDTGTYV-DWQGQSILPAASTIKVPILVAFFQDVD -AGKIRLDEPLTLEPDVIGTGSGELQQKLGHQYTALEVVTKMSAISDNTATNMIIKRLGGA -AVLNQRFRSWGLTATVINNPLPDLEGT------NTTTARDLGNLMGMVNQGQLLSLRSRD -RLLNIMQQTVN-NSLLPKGLGSGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIIVTMVKR -PHND-ASASELIRNISRTVYNYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V578_9BACT -------------------------------------------------VMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWTV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-2098 TaxID=1954171 RepID=A0A1Z4FTT0_9CYAN --kALEPQIKALMNRYSLQTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDETLTMRGDLVTNGSGVMQERVGKKYSALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSESSKE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf339 TaxID=1736343 RepID=A0A0Q6KCY5_9SPHN ---ALQASIETLARNFDGRAGIAVRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITVLDQRD -QGKVRLDQPITVLPTDLTLHQPIAYLVAKTGTTVGGLLTRALTQSDNTANDRLLTLVGGP -EAVRRMIAAKRLGDIRFGPGERMLQARYVADPPDGAAPLAIADAISRVARGELLSETSTR -ILLDTMGASITGRARLRAAIPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD -TRRPIRERQMLIQNVAATVAS-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Dysgonomonas sp. HDW5A TaxID=2714926 RepID=UPI00140A6885 --nTLRQEIQDIIQNKKATVGVAII-FDGKDTL-TVNNQYRYPTMSVYKFHQALAVLDYLD -KYNLPLEQQVYVSKSALHPYSPLRDKKPEGNMPIKELMQYSVSQSDNNTCDILFNFLGGT -TPVEQYIKGLGIQQIAITKTEKEMSEDFDNQYGNWTTPYAAVQLLEIFLQQELFASHYKN -FLLDALIQTSTGKDKIKSLLPARTVVGHKTGMSSKAGDNDLGFIKLPNDKNLSIAVFIVN -SIENDTTNAEIIAQISKVTYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingosinicella vermicomposti TaxID=614671 RepID=UPI000D0FDF4B --rALSQRINALGSSFNGDIGIAVKDIQTGFTT-AYDGSTFFPQQSVSKFWVALTALDRAD -RGLLSLEAPVTVTRSDLTLHQPIAAQVGANGTTINSLMYRAITQSDNTCNDFVLWKAGGP -DAVRSFLANKGIGGIRFGPGERKLQSNYIRDPMDGATPLGTVDALARLKKGELLSPYYTQ -KLLDIMSNTRTGAQRLKGGLAPGWKLAHKTGTGQQAGYNDIGIVTGPDGRSYAVAVFIRR -TSAPLGHRMSTMQNVVRAVVDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A059ULV6_ECOLX -------------------------------------------------VLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKV------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_C_20070703_M131 TaxID=2486263 RepID=A0A551X6L3_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDESLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] class A beta-lactamase n=1 Tax=Undibacterium sp. KW1 TaxID=2058624 RepID=UPI001331E55A -----QNVIESIAMDSGGRLGASLLVLETGQSL-WILPDTAAPMQGVSKLPIVMAALAAVD -KNKLKLDQKVTINKEDLIPPSALRDEHPEGNITAKELMHHAIVDNDGTASDALLRLLGGP -PAVMQYLAQLDIKDIKVLDTEKDLAKSWNMQYRNTATPKAMIKLLQTVQEGKALSPKSRE -LLLKWMTDTEVNAARIKALLPAGTAVVHKAGSSPTAAHNDVGIVTLPNGHHMAVAVFLTD -SKAPHASRDLTIAKITRVGWDAw ->[subseq from] Uncharacterized protein n=3 Tax=Luteibacter rhizovicinus TaxID=242606 RepID=A0A1L3ESC0_9GAMM ---RLQASLDRIASEAPGTLGIVVMDPSTGKSI-KVNDGRSYLMMSAFKAPIAAAVLARVD -SGELKLDQKVHLVPADIVPGSPSLGKRLEAGVSVEEVLRAAVTQSDNTAVDALLRLLGGG -HAATAFLESKGVHGMRIDMGERELSLAVLASKVDSTTLDAAATFLDKLQSGALVSSSSTN -MLLGMMTAQVI-PNRVRAGLPVGFQLADKTGTAGLGAWNDMGIVTAPNGRRMVVAVFLSD -SPAKPKQADAWFAEIGKAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Herbaspirillum sp. B39 TaxID=95609 RepID=UPI0005538D04 ------------------------------------------------------------- ------------------------------------QLCEAAITLSDNTAANLLLESMDGP -AGMTRFVRSLGDELTRLDRNEPTLNEAVPGDPRDTTTPAAMTADLRQLVLGNALTPASRQ -QLAQWLVANQTGDKRVRAGLPKGWKVGDKTGTGRLGTANDVGVVWTEKGAPLLFAVYLTE -NAATDARRD-------------- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A380E9A1_STAAU ----------------------------------------------------------QVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas turrisvirgatae TaxID=1888892 RepID=A0A1E3LV03_9SPHN ---TLSSTVTSLARDFGGVVGISVRSIDWGWQI-DANGNRRMPQQSVSKLWVAMTVLDARD -KGRLTLDDPVTLTRENLTLHQPIAALVVKDGTTVRELLLRAMQQSDNTANDRLLTLVGGP -EAVRAFIRERQLGQIRFGPGERLLQAAYVADPVDGAAPSAIALALARLKAGELLSPSSTH -FLTTVMSGTRTGRARLKAAVPPGWSLAHKTGTGQTAGFNDIGILTAPDGKSYTLAVMIGD -TARVPRDRQLLMQAVVTAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520FLL5_SPHSX ------------------------------------------------------------- ----------------------------------AAKVMELMIIHSDNQATDNLLAALGGP -VAIQQWLWSQKITGIRMDRTIAQLLRGHLADSKDVTTPVAMVTLLNKLDNGSVLTAQSRT -FLLELMSRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] serine hydrolase n=1 Tax=Bhargavaea sp. CC-171006 TaxID=2302363 RepID=UPI0012FB85E1 ---RLQKKIEKLLNETDATFGISIKHLQSGEEV-RIHADEPFQMASVFKVPILLALFEQVH -EGRIDLTTRIALTEEERVPGSGILQELDPGLLTIKDLATLMTIVSDNMATDVLLGML-GK -NAVQDTVRKLGAENMMIVHSCWELLSMRTDRANNLCTPDDMTAILSKLAEGAFISPAVSD -TVLDILYRQQL-NDRLPARLPAGTKVAHKTGTIAS-AVNDSGIIDLPGGARLIISIFSSG -NP-TTESGETVIARIAETAYQYf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XD23_9BACT --eKLAERLRSMIEAAGGDVGLTVIHVESGRTV-SIHGDIQLPLYSVFKLPLAVAVLKDVE -EKRLQLDHKVVTSPTEIVPGSQENTDLWRKPRTVAELLELSISRSDNTSADKLLKLVGGP -EAVTNRMRSLGFPNFMIHSSVSEYVKD--RSKVNTGTASELGRLLVELQQGHVLQKPQLS -VLLGFMERATTGNHRLRGLLPAGTLVADKTGTGEAGATNDVGLITLPNGGHLAIAVLIKA -SKLAPTEQEKLIAELARVSYEA- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis sp. M_OC_Ca_00000000_C217Col TaxID=2486213 RepID=A0A552AB86_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMEYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis flos-aquae DF17 TaxID=2060470 RepID=A0A3E0KV31_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Aliterella atlantica TaxID=1827278 RepID=UPI0005D39EA4 ----LKAAVQQLSTKNGLTPGIFFVDLDTNNYL-DWNGSLTFAAASTIKFPVLVAFFQDVD -AGKIRLDEKLTLKKELIGGGSGDMQYRPGTKFTALTTAAKMIIISDNTATNMLIARMGGI -AALNDRFKNWGLGSTIIRNQLPDLPGT------NITSPKDLAHLMQLVDKGELMSLRSRD -RLLDIMRQTKT-RTLLPRGLGEGSTIAHKTGDIGS-MVGDVGLIDMPNGKRYVGVAMVKR -PHND-SRAQELIRQISRSVYQHf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides intestinalis CAG:315 TaxID=1263048 RepID=R7DLU5_9BACE --qKIEQQIDSFLKDKKATVGVAVLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI -DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNIADKQPLFATQYKD -FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSNRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase class A n=1 Tax=Altererythrobacter xiamenensis TaxID=1316679 RepID=A0A1Y6FIF9_9SPHN ---TFEQELEELGAGLPGEVGIAVVDAKTGYSY-DFDGEEILPQQSVSKLWVTMAALDAVD -RGTLDLSERVTVRREDLTVYQPIRDLVRARGTDYGDLMRRAITRSDNTANDLLLRRVGGP -EKVQAYLDARGIENVRFGTDERTKQSRYLADPIDGASPLGIARALAMLSRGELLSPGSTA -FLLDLLSQTKSGPNRLKGGVPPDWSFGHKTGTGQQSGYNDIGLLTAPDGRTYAMAVMIGR -TRVPTPERMEMMQEVVRATV--- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. TZW2008 TaxID=1917973 RepID=UPI001181ADDC ---QLTASIQQLVREFPGTAGVAIRAVDEGWTV-QANGRLKLPQQSVSKLWVAMTVLDQRD -QGRLRLDDPISVTPADLTLHQPIAYLVKGGSTTVGNLLFRALTQSDNTANDRLLTLVGGP -SAVRDFIERKQLGDIRFGPGERLLQARYIVNPPDGAAPLAIADALARLFRGELLSETSTR -LIVSTMESSRTGRARLKAGIAPGWTLAHKTGTGQNAGFNDVGVITSPDGRRYAVAVMIGD -TTQPMRVRQQLIQAVAATVT--- ->[subseq from] serine hydrolase n=1 Tax=Richelia intracellularis TaxID=1164990 RepID=UPI0012DF4380 -----------LANNTKLTPGIFLVDLDNGNYV-DFNAANSFPAASTIKMHILVAFFQDID -NGKIRLYEQLTMEKGLIVGGSGNMGQKPGTKFTALEVATRMMTTSDNTATNMLIKRMGGI -DVLNQRFRSWGLSITTINNLLPDLKGT------NITSPKELGELMAMVSKGNLVTMRSRD -RIMDIMRRNTR-NNLLPAGLPKGATIAHKTGDIGS-MLADAGLIDLPTGKRYLAVVMVQR -PYND-PSAETLIKSVSRIACQQf ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9443 TaxID=1160281 RepID=I4GBM6_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=bacterium TaxID=1869227 RepID=A0A3N9MWA4_9BACT ----LADEIKRIIKLCKSTVGVGIVHIESGLSW-YNNREVSFPMASTYKIPIAMKLLKDVE -SGVLVMEDMISIKQYDQHPGSGILSELIDNPLSIANLFELMMTISDNTATDIILSLVGGG -GAVTDYLKSLEITGMTVDRSTLEMLSEFLNIHKDVTTPEAMSRLLGKIMIEGVLNRTHIE -ILLDAMRKNKYGDDRIKGFLPPHVIVAHKTGTLGT-ITNDAGILTLPNDGHIALVVLIKK -SDDSNAEREATIAHIARATYDYf ->[subseq from] Serine hydrolase n=3 Tax=Sphingomonas TaxID=13687 RepID=A0A0Q6AFY2_9SPHN ---ALVQAINALGGGFQGHVGIAVRSIDDGWVV-GHAMDRRMPQQSVSKLWVAMTTMSAID -EGRLALTTPVAITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTMSDNTANDKLLNLVGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHRMLLSQQSTA -WLLDTMAHTRTGRARIRAALPPGWSVAHKTGTGQTAGFNDIGIITAPDGKAYAIAVMIGD -TARPVPERQQLIQTVVSSIV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Granulicella pectinivorans TaxID=474950 RepID=A0A1I6LTI9_9BACT --qTLQQKLAKIAASANETVSVACALPNSTLNC-DLNPDGHPPMQSVFKLPLGVAMLHLVE -QGNFTLDQPIRFLPSDRIQYSPLQDKYPDANVPLRELIRLSVYLSDNAAADTLLRLLGGT -AALQKYMDTLGIQGFHIEDTEYSLHTDAQFQFRNWFTPRAAVSFLRLLADNSPLTPEHTQ -LLFSFMQGPGNGTGRIKAGLPADTVVRHKSGTSDY-AMNDIALITLPDGRTLALAVFLTN -STDSQKDREATIAAIAKAVYE-- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. B(2019) TaxID=2690446 RepID=UPI0013919CE7 ----LEPQIQALKARYSLKTGMFFLDLDTGNYL-DVGGDRIFPAASTIKLPILIAFFQDLD -AGKVTLNEMLTMRRDLVTNGSGTMQERVGKKYTALETVTKMVTISDNTATNMIIDRLGGA -ARLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMTRALALLVNNKLVSPESRE -QALDILYRTVT-NTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVRR -PYKD-TRGRDFIRQVSQLVYNY- ->[subseq from] Putative beta-lactamase n=1 Tax=Planktothrix agardhii CCAP 1459/11A TaxID=282420 RepID=A0A479ZPV6_PLAAG ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRQISSTIYQYf ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009ECA5F1 ---ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMSAID -EGKLALTTPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS -WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TARPVQERQQLIQTVVSAIVA-- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides plebeius TaxID=310297 RepID=A0A414QT22_9BACE --qELYTNIHQFISQQKAEVGIAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGNYCK -RHQLSFDTLLTVDSTDLQPYSPLRDRYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AVTDRYIRSLGVNDFSIQYTEDDMHRDLNLGYENWSTPLAAAEVIEALLTRTLFDKPHQE -FIKEALITCQTGTSRIVHPLQKQITVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] serine hydrolase n=1 Tax=Anabaena sp. PCC 7108 TaxID=163908 RepID=UPI000475627D -----KTSVQNLATASNLTPGVFIVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD -AGKIRLDEMLTLQQEMIAGGSGTLKSRVGTQYTTLEIATKMITISDNTATNMLIARLGGK -DVLNERFRTWGLTTTMIRNSLPDLQGT------NTTSPRELGNLIFMINQGNIVSMRSRD -LMLNIMSRTER-DNLLPSGLGQGSRAYHKTGDIAT-MLADAGLIDIPSGKRYIATVMVQR -PTND-PRAEKLISSISAAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium artocarpi TaxID=1414727 RepID=A0A1B9A058_9FLAO ---EFKKIIESIIANKKADIGVSIFISGTKKEVtQINGNNLYPMLSTFKFHIALAILHKVE -KGELSLQQKIFIKKEELLEYSPFKEKYPEGNLTLEEALQWIVIYSDNNLTDILLRLIGGP -QYVEKFINS---KNVIIKNDEEDMHKDWDSQFINKTTPNETIRLLQDFYNGKILNKEHTK -WLYTNMMSTASGAKRLKGKLPQNIKMAHRTGTSFTGAINNFGIIELPNKKNIYIAVFVHD -TYETFNNSEAIIADISKATYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWA2_62_23 TaxID=1797924 RepID=A0A1F9REV9_9BACT ---------GKTSVAYRGRVGIYLKDLHTGKTW-EYNADRLFPSASLIKVPIMAAVFEKIK -LGSITLDTQIKLTRKGRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDYV-GM -DYLAMTFARLGLEHTNITPEGMSLTSG-RVKNENFTTAREMAGLMERIYQGELVNRDASE -FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-SCHDVGIVFSPRGD-FVIAVLTSN -VP-DYRSAKNFIARVAKLTYRYy ->[subseq from] Beta-lactamase n=1 Tax=Alphaproteobacteria bacterium TaxID=1913988 RepID=A0A537MKH7_9PROT ------------------------------------------------------------- ---------------------------------TARVLMEAMIIHSDNRATDMLIATLGGP -SAIDSWLRAHRLSGIRADRTIATLLSDRRTDVRDSSTPTAMLGLLRAIDSGEALTPQSRA -HLLDLMRRCATGTNRIRGLLPPEARVEHKTGTLN-GYTGDVGYLTYPDGRRIAVVFFARG -GS----NRPGVISTAARAIYDGf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa TA09 TaxID=2060472 RepID=A0A3E0L7S4_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_59_12 TaxID=1797946 RepID=A0A1F9UG29_9BACT ---SFTAALRQRSVRFQGSVGYVVKDLRSGEIV-AINQDRVFPSASLIKLPILVAAYQAVE -DGRASLSQPITLHRRDRRGGSGILKWAMPGTFTLRELLEYMIIHSDNTAAEMVIQRL-GF -DYLRHTFDRLGLQDTEIHPDGFRLTGR-RVAEDNRTSPRDMAYLLEKIYHGGLVSRDASE -DMLRILKHQKL-RDRLPRFLPTGWQIAHKTGLLRR-ACHDVGIVFSPQGD-YLICVLTSH -QA-TYKNAKRFIASLGRITYDYy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas turrisvirgatae TaxID=1888892 RepID=UPI0009A1B113 ---TLSSTVTSLARDFGGVVGISVRSIDWGWQI-DANGNRRMPQQSVSKLWVAMTVLDARD -KGRLTLDDPVTLTRENLTLHQPIAALVVKDGTTVRELLLRAMQQSDNTANDRLLTLVGGP -EAVRAFIRERQLGQIRFGPGERLLQAAYVADPVDGAAPSAIALALARLKAGELLSPSSTH -FLTTVMSGTRTGRARLKAAVPPGWSLAHKTGTGQTAGFNDIGILTAPDGKSYTLAVMIGD -TARVPRDRQLLMQAVVTAIVA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Hyella TaxID=945733 RepID=A0A563VKI7_9CYAN ----LQKQLQILTDRYQLEPGILIADIESKDYV-NLGGTDTFAAASTIKIPILVAFFQDVD -AGKINLNQPFTITKESIADGSGYMQYQPGTKFSALKIASSMITVSDNTATNILIEHLGGK -KALNQRFADWGLTTTQISDRLPDKQGT------NTTSPEDLSNLLLKIDRGELVSLASRD -RILAIMKQTER-NTLLPQGLGKDAAIAHKTGTLLS-VLGDTGIIYTPNGKRYIASVLVKR -PDND-PQAESLIQEISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Granulicella sibirica TaxID=2479048 RepID=A0A4Q0T8J2_9BACT ----LKQAIATIAADSDSTVAVACALPNAQLDC-SLNADSHPPMQSVFKLPLAVTVLHFVE -QSKLSLDQQVRFLPADRIPYSPLQDEHPAPNVSLRELFRLAVNLSDNVAADILLRVIGGP -QVVQAYITSLGIKDFHIVDGEHGLYLDAQNQFHNWISPSAAVQLLRLLADASPLTPADTQ -LLFGLMETSPMAPHRIRDGVPPGTVVRHKGGTSQY-ATNDVALITLPDGRTLALAVFLTN -STDDDKTRDATIASIAKAIYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Myroides marinus TaxID=703342 RepID=A0A1H6SUI0_9FLAO -hqELNNKIKGVISNKNATVGVAIIY-DAKDTL-TVNNDHKYPTMSVYKFFQALNILDYMD -KHNISLDTEIYIKKEDLKEYSPLRDKSPKGEMSLRELIQYTASHSDNNISNLFFRSFIGP -KMTDLYFRSLGIQNFEIVSSEETMSLDFNNQYQNWITPLEATRILEMFRKEELLSPDYNN -FLRQAMIDTKSGQDKVKALLPKNTVVVHKTGMSFRAADNDLAIVYLPNGKQFSIAVFIMN -SKESDKTNASIIAEIAKLAYDYf ->[subseq from] Putative beta-lactamase protein n=1 Tax=Gloeothece citriformis (strain PCC 7424) TaxID=65393 RepID=B7KDD6_GLOC7 ---SLEKKITDLAAKYKLQPGSFFVDLDNGAYI-DVNGQAPFSAASTIKIPVLVAFFEDVD -AGKIYLDEELVMTKDVIGSGSGDMQYPVGKKYSALETAAKMNIISDNTATNMLIKRLGGK -EALNERFKAWGLTQTVINNPLPDLEGT------NTTSPRDLAYLLARVNQGEILSLRSRD -RLMGIMQKTKT-RTLLPQGIEKDAIIAHKTGDIGT-VLGDAGIIDMPTGKRYVGAVLVKR -PHND-YSARTLIQDISRTVYQHf ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium ureilyticum TaxID=373668 RepID=A0A1N7KBQ0_9FLAO ---EFKKIIESIIANKKADIGVSIFISGTKKEVtQINGNNFYPMLSTFKFHTALAILHKVE -KGELSLQQKIFIKKEELLEYSPFKEKYPEGNLTLEEALEWIVIYSDNNLTDILLRLIGGP -QYVEKFINS---KDVIIKNDEEDMHKDWDSQFINKTTPNETIRLLQEFYNGKILNKEHTK -WLYTHMLNIASGAKRLKGKLPQNIKIAHRTGTSFTGAINNFGIIELPNKKKIYIAVFVHD -TYETFENSEAIIADISKATYDYy ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter steynii TaxID=430522 RepID=A0A1H0JQV5_9SPHI ---QLQERIKHIIDTAGGKIGVGVKGMDFKGGF-VINNNHGYPMMSVFKFPLAFAILGKVD -KGELQLSQKFHMPKETLDTWSPMVKDFPNQDMTLADLLTYTVSKSDNNACDFLYTKVGGP -AAVNQYLHNAGVKEISIVYTEGEMEKDWALQYKNWCKPAAALQLLQLLYNQKLLSKSSND -FLMQIMRELPDWGKRITVLLPPATELIHKTGASGANAFNDIGIVTLPDGKHLAISVFVSD -FKTPKERGINVIAAISKEIWDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=G5CK57_PSEST ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPIDKRDSTLP---------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. ERG5 TaxID=1381597 RepID=UPI000691C90E --qALVTNIAALGRSFNGRVGIAVRSVDNGWSV-QTNGDALLPQQSVSKLWVAMTVLDFRD -AGKLRLEDPVTLKPEDLTLHQPIAALIKADGTTIGALLQRALTMSDNTANDRLLRYVGGP -KAVRAFIQRKQLGDIRFGPGERLLQSRYVTDPPDGAAPMAIAGALMKLKRGELLSASSTE -YLIGTMQSSKTGKMRLRGAVPEGWSFGHKTGTGQTAGYNDVGLLTAPDGKSYALAVMIGD -TPRPIPDRQALMQAVVAAVV--- ->[subseq from] Beta-lactamase n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=A0A0A1VYH0_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis wesenbergii Mw_MB_S_20031200_S109D TaxID=2486241 RepID=A0A552LWF9_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A0G3VQK8_ECOLX ----------------------------------------------------CGAVLSRVD -AGQEQLDRRIHYSQNDLFEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLR------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381RP82_9ZZZZ ---RLRGALLAIAQRFPGDVGVYVHHIESGMET-GIDEDTPYGMASTYKVPILVELMTRVE -AGDLSLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA -DQITAQMRSLGFQNIRVDRTTLELILGFYGGDKDKASARDMTELLVMISEGTAVSRGSSE -VIMEILARTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGEGRFAISVFTFA -NEADTELGEHTIAEIARTAYDFf ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa (strain NIES-843) TaxID=449447 RepID=B0JWL2_MICAN ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. 39-10 TaxID=1895745 RepID=A0A1M3E2X0_9FLAO --sALSQRISEISAQKKATVAVSVIGIDFPFDLnNENADRKLPMLSVFKFHIALTAMHYVD -QGKLKLDQAFFVKKEELLPYSPLRDKQPDGNLSLAELLYYSVSLSDNNTTDILLRILGGP -KTVQQFMEEKKVKNLRIQYNEEEMHRNPKYFYGNYTSVKSLSKLYKSFYNGKILSKKSTE -YLYHILQQTTTGSNKLVQQLPPD-SVAHKTGSSGKDAENDSGIVALPNGRHYAISVFVND -SYESETVNCQMISDISKAVFD-- ->[subseq from] HGF-1 beta-lactamase n=2 Tax=Parabacteroides TaxID=375288 RepID=R5DKF0_9BACT -------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD -REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI -KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTEKILSATSFA -FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN -SLESDETNARIMADITRVIYH-- ->[subseq from] Penicillin-binding protein n=1 Tax=Aphanizomenon flos-aquae 2012/KM1/D3 TaxID=1532906 RepID=A0A0B0QL49_APHFL ----LKNSLQTLTTNADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD -AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C6IVT8_9BACE --qKIEQQIDSLLKDKKATVGVALLA--NDEIVaVYNNQIHFPLLSVFKFHVGLAVLDKMD -KDHIGLDSLIEVKSSQLKPYSPLRDEFPDQDISLGELLKYTISKSDNNTCDILIEYVGGI -DQVNEYVKSLGIKDCNLAATETLMHTS-GDAYLNWSTPEEVVRLLNITDKQILFGTQYKD -FLQATMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQETDADNAAIIASISKIVYDT- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649Z3N8_PSEAI ------------------------------------------------------------- ----------------------------PGGTLTLRELCRAAVSISDNTAANLALDAIGGA -RTFTAFMRSIGDDKTRLDRREPELNEATPGDARDTTTPIAAARSLQTLLLDGVLSAPARN -ELTQWMLGDQVADALLRAGLPRDWQIADKSGAGGHGSRSIIAVVWPPKRSAVIVAIYITQ -TAASMSASNQAVSRIGSALAK-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium hotanense TaxID=649196 RepID=UPI0011F363A4 --eQLKIAIDSILAKYQAKVGIAIHNHDYTDSL-TVNGDFHFPFQSVYKFHLGIVILDQVD -KGKLSLDQPIKISKEAVTTYSPIKDKYPNGILPLREVLEYTIAASDNVGCDVLFELLGGP -EYVQKYFEDKGYSNLSIKLIEAVQQKEWNRQFENWTTVGSSNQILYDYYTKKLLSASSHQ -FLWDTMRGTTTGPDRLKGDLPKGTVVAHKTGYSGRNALNDVGVVSLPNGEVYYISVFVTD -SEEGEAGSAKIIAEVSAAAWKYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A166H5B8_KLEOX ----------------------------------------------------------RSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTNGNHRIRAAVPADWAVGDKTGTCGYGTAND-------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E1KFN0_9PLAN ---SLDSQLRALLDGHEGKAAVAIKHLTTGEQF-TFRENETMPTASLIKLAVMIETYRQAE -TGRVDLDRRITLKDEDKVAGSGILTPHFSAGISXRDAVQLMIAYSDNTATNLVLNQI-GI -KSTSETMEKLGFPNTKIHAQVFRRETVFPNRSRGSTTASETIGLLEQLYRAKLASPTSTQ -AMLTHLEACQD-RTKLPRLLNPQIRIAHKTGSVSR-VRADAGLLFXPSG-PIAICVLTSD -NKTDENAGDVLCAKVAEXAFHHf ->[subseq from] Beta-lactamase AST-1 n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251Z4K1_9MICO ------------------------------------------------------------- -----------PIEAADILSYAPVTETRVGGTMTLRELADAAMTRSDNTAANLLLEALGGP -AELDAALTALGDDTTVVSRTEPDLNEATPGDDRDTTTPRAAAAYLRAYALGDPLDADERT -LFTGWLTATQTGGTLVRAELPAHWTVGDKSGSGAYASRGDIAVIWRPDAAPLVIAVHSSK -DQQDADADDALISGAAKAAVE-- ->[subseq from] HGC-1 beta-lactamase n=1 Tax=Bacteroides plebeius CAG:211 TaxID=1263052 RepID=R5VVI2_9BACE --qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGDYCK -KHQISFDTLLTVDSTDLQPYSPLREQYPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -TMTDRYIRSLGVNDFSIQYTEDDMHRNLNLGYENWSSPLATAEVIEALFTRTLFDKPHQE -FIKEALITCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQTf ->[subseq from] serine hydrolase n=1 Tax=Aphanocapsa montana TaxID=327565 RepID=UPI00140AB42E ---QVKQEVEALAQAQGLETGLFFLNPETQEYL-SIRGSEAFPAASTIKLPILIAFFQEVD -AGRVKLDEQLVMREDLKVGEAGSMQSEVGSKYSALETADMMITISDNTATNMIMDRLGGN -QVLNERFKSWGLEQTRINQPLPDLEGT------NTISPKDLAILMMKVSQGDILTAHSRD -RALEILRNTVT-DTLLPQGLEPGAQIAHKTGDIGS-AVGDAGLIDMPNGQRYVAGIMVKR -PHND-PRAQELIRNISRLTYQAf ->[subseq from] Uncharacterized protein n=1 Tax=Myroides marinus TaxID=703342 RepID=A0A161S1I8_9FLAO -hqELNNKIKGVISNKNATVGVAIIY-DAKDTL-TVNNDHKYPTMSVYKFFQALNILDYMD -KHNISLDTEIYIKKEDLKEYSPLRDKSPKGEMSLRELIQYTASHSDNNISNLFFRSFIGP -KMTDLYFRSLGIQNFEIVSSEETMSLDFNNQYQNWITPLEATRILEMFRKEELLSPDYNN -FLRQAMIDTKSGQDKVKALLPKNTVVVHKTGMSLRAADNDLAIVYLPNGKQFSIAVFIMN -SKESDKTNASIIAEIAKLAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. S-NIH.Pt1_0416 TaxID=1920123 RepID=A0A430CSC7_9SPHN ------SAINSLSASFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -QGRARLDEPLVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTYVGGP -QVVRTMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILLDTMEASRTGHARLRAAVPSGWKIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRLRQRLIQNVAAAVAS-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A411LP21_SPHPI ------SAINSLSASFSGKKGIAVRAVDDGWTV-EVGGRQRLPQQSVSKLWVAITLLDLRD -QGRARLDEPLVVRREDLTLHQPIAMLVKGDGTTVGELLTRALTQSDNTANDRLLTYVGGP -QVVRTMIANKRLGDIRFGPGERLLQAAYVNDPPDGAAPIAIADALARLARGELLSETSTR -ILLDTMEASRTGHARLRAAVPSGWKIAHKTGTGQNAGFNDVGLLTAPDGRRFAIAVMIGD -TTEDIRLRQRLIQNVAAAVAS-- ->[subseq from] Serine hydrolase n=1 Tax=Richelia sp. TaxID=2053605 RepID=A0A3B9F8Y1_9NOST -----------LANNTKLTPGIFLVDLDNGNYV-DFNAANSFPAASTIKMHILVAFFQDID -NGKIRLYEQLTMEKGLIVGGSGNMGQKPGTKFTALEVATRMMTTSDNTATNMLIKRMGGI -DVLNQRFRSWGLSITTINNLLPDLKGT------NITSPKELGELMAMVSKGNLVTMRSRD -RIMDIMRRNTR-NNLLPAGLPKGATIAHKTGDIGS-MLADAGLIDLPTGKRYLAVVMVQR -PYND-PSAETLIKSVSRIACQQf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_C_20070823_S13 TaxID=2486246 RepID=A0A552GR55_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=bacterium HR08 TaxID=2035403 RepID=A0A2H5VNL1_9BACT ---EVKARIERAIAASGAEVAVAYADLATGEEL-LLRADEPFHAASTMKVAVMLEVFRQAQ -EGRLSLEDRLVVANDSLADGSSFSYERIGQAVTIRELVRAMITRSSNLATNLLIERV-TA -ARVQQLMREMGIEGMRVLRGVEDRR-AFERGLNNTTTARALLLLFRRLAEGRAISPESSA -EMIRILLDQEF-NDGIPAGLPAGVRVAHKTGTIAR-IAHDAGVVYPPIGPPYVLVVLTRG -IA-DERDAHRLIAEISRLLYEH- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf62 TaxID=1736228 RepID=UPI00070174AA ---ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGKLALATPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS -WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TARPVQERQQLIQTVVSAIVA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH10-B3 TaxID=1768757 RepID=UPI0009E99F4E ------AAVGTIARGFDGKVGIAVRSVDRDWMV-SANGDLPLPQQSVSKLWVAMAVLDARD -QGRLTLDDPVTVTREDLTLHQPIAAMVRGDGTTVGDLLQRALTESDNTANDRLLRLIGGP -DAVRAFIARKDLGTIKFGPGERLLQSAYVADPPDGAAPIAIAGALAKLKRGALLSPGSTQ -YLIGTMESSKTGRQRLRGAVPIGWSFGHKTGTGQTAGYNDVGILTAPDGRSYALAVMIGD -TPRPIAERQALMQSVVAAVVA-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Tolypothrix sp. PCC 7910 TaxID=2099387 RepID=UPI001427814C --kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE -QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR -PYKD-TRGRDFIRQVSQLVYNY- ->[subseq from] HGB-1 beta-lactamase n=1 Tax=Alistipes sp. CAG:268 TaxID=1262693 RepID=R6W363_9BACT --eQFERRIDRILEPCEATVGVAVLAPD-GTPI--TRNDRPLPMLSVFKFPVALAVLDRAV -REGIPLSTPVAVGPEWLDSYSPMRDSLPPQGLPLGRLLAYAVSQSDNIACDRLIDFAGGP -GAVDRYLKRLGITEIRITATERTMHLATENQRINTARPSALCSLFDRFLQGELLPQRETA -WLRGLLEGCATGRNKLRAGLPPEVRLGHKTGSSDRTADNDAGYVVLPDGRHYCITVLVTD -SHHDDARNAGVIAAISEAAYEYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y0U8_9BACL ----WQQAVENELKEAPGIFGIAAVHVETGETA-GHLDEELFQLASAFKIPIMVTLMSEVE -AGRIRLDQRVTLKWEDRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDQILELIGGI -DKVNKHMHELGLSQIHLRHNCWELLNSMPTCDNNVATPAELNRLLIMIARKEILTETSCE -LMQDIMRRQHY-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGIIYLPEGKGMIAITALSR -GVTDTEAAELTIARVAKAIYE-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostocales TaxID=1161 RepID=UPI000BBCC8BD --kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE -QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa SPC777 TaxID=482300 RepID=S3JDP8_MICAE ---SLNQKLQALAVKYKLQTGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=A0A0Q4JQ43_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -VAIQRWLSSQNIPGIRMDRSIAQLLRGHLADIKDVATPIAMVTLLNKLDNGTVLTPQSRA -FLLGLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVARVIYNRf ->[subseq from] Serine hydrolase n=1 Tax=filamentous cyanobacterium Phorm 6 TaxID=2107706 RepID=A0A2T1FAR7_9CYAN -----KTQVQILATENTLTAGIFLVDLDTGSYL-NFNGDTPFASASTIKLPILVAFFQAVD -EGKVQLDQMLTLKAEHIVGGSGEMQDAPGKKYSALEVARKMIVVSDNTATNMMIELLGGA -EVLNQHFANWGLRATVLRNNLPDLEGT------NTSSPKDLINIIAQVDRGNLVSVKSRD -RILQIMRQTQN-DSLLPRGLGEGAVIAHKTGNINI-MLADAGMVDLPNGKRYLVAVMVKH -PAETEKPAQTLIRDISRMSYRY- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis flos-aquae TF09 TaxID=2060473 RepID=A0A3E0LBT7_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-4285 TaxID=2497681 RepID=A0A402DAZ1_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Synechocystis sp. PCC 7509 TaxID=927677 RepID=UPI000311D215 ----LKAAVQQLGKNKGLTPGAFFVDLDTKNYL-DWNGSLPFAAASTIKVPVLVAFFQDVD -TGKIRLDEKLTIEKKIIGGGSGGMQYPLGTKYTALNTATQMIVVSDNTATNMLIKRMGGI -KVLNERFQAWGLESTKINNLLPDLTGT------NTTSPKDMGNLMSLVDRGELMTLRSRD -RLLEIMRRTKT-RTLLPQGLGEGAIIAHKTGDIGS-MVGDVGLVDMPNGKRYIAVAMVKR -PHND-SRAQELIRQISRLSYQQf ->[subseq from] serine hydrolase n=1 Tax=Trichormus sp. NMC-1 TaxID=1853259 RepID=UPI0008DBE919 --------VQNLAAQANLTPGVFMVDLDTGAYV-DINSNASFSAASTIKVPILIALFQDVD -AGKIRLDEMLTLQQEMIAGGSGTLKSRVGTQYSALEIATKMITISDNTATNMLISRLGGK -DILNERFRTWGLATTMIRNSLPDLQGT------NTTSPRELGNLISMINQGNIVSMRSRD -LMLNIMSRTER-DHLLPSGLGQGSKAYHKTGDIAT-MLADAGLIDIPSGKRYIAAVMVQR -PTND-PRAEKLISSISAAAYQQf ->[subseq from] Class A beta-lactamase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V2DBU3_9BACT --qNMAQDIEKIIKEKQASVGVAVIH--NDGIF-TIANDDKYPTMSVFKLHVAVTALKKME -NENIPLDTKAYIEQKEMLKYSPLRDKYPDQGISYRDIIDYTVKISDNNTCDWLIRFVGGI -NKVNSYIKSIGIKEMNFTETEESMHTDIMRCYNNWSTPLAVAQLLKKIYAENLLAKEHFT -FLETSMLNCVSGKNKLIAGLPHDIKFGHKTGHSDRTSEADAGVIYLPNGEKCYIVVLIKD -SRESDDDNAKIMADISNAVYRY- ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter luteus TaxID=1581420 RepID=A0A0G9N1B3_9SPHN --qELTGLLETIAADFGGTTGIAVVDLEDGWST-GVNADALLPQQSVSKLWVALTALDRVD -RGTLTLGDRITIARQDLTVHQPIREEVLRAGINPLDLMTRAITRSDNTANDALLWAVGGP -DAVRAMLRDKGIAKVRFGPGERLLQSSYLADPVDGASPRAIATALARLARGELLAPPTTK -LMLDTLRETRSGPRRLKGGLEQGWSIAHKTGTGQYYGYNDVALLFAPDGRTYAVAVMIGE -TRQGVPGSTAMMQKVTRAVED-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf22 TaxID=1735687 RepID=A0A0Q4GT69_9SPHN ---ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGKLALATPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS -WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TARPVQERQQLIQTVVSAIVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella oxytoca TaxID=571 RepID=A0A1W6AKY9_KLEOX ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGNETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYG------------------------ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Nostocales TaxID=1161 RepID=A0A1Z4N466_9CYAN --kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE -QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Class A beta-lactamase n=1 Tax=Elizabethkingia occulta TaxID=1867263 RepID=A0A1T3M9C8_9FLAO --pQLKKTLESIISGKKSIVGISVMSPDEKEMT-GINANQMLPMLSTVKFPLALAALHEVE -KGKLSMNQKLFIKKEELLDWSPFKEKYPAGNITLEEALKWTVSYSDNNLTDILIRLIGGP -ETVQEFMDS---SSFIIKNNEEGMHKDWDSQFINKITPNFAVLLLQEFSNSKILNKTNTQ -WLYNAMLNNVSGKKRLKGNLPTGVKVAHRTGTSFTGAINDYGIIELPGKKKIYIAVFVHN -TYESFDDSEKIISDIGRAAYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E7AQ56_9BACT -------AXLAIAQRFPGDVGVYVHHIESGMET-GIDEDTPYGMASTYKVPILVELMTRVE -AGDLSLDDRVAVEAEDQHIGSGLLSTLWAPGMSLRNIATFMIILSDNSATDMLIDRL-GA -DQITAXMRSLGFQNIRVDRTTLELILDFYGGDKDKASARDMTELLVMISEGTAVSRGSSE -VIMEILARTQTGANRLRGLLPPGYSIAHKTGTIGR-IVNDVGVITMPGDGRFAISVFTLA -NEADTELGEHTIAEIARTAYDFf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9G449_9BACT --qKLEAAIQDIDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ -QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM -ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMLLLENLYRGKVLNKQFTE -EFFNLLSIHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY -LRREH-DGGEAIIRISNAAYQMf ->[subseq from] Beta-lactamase n=1 Tax=Parabacteroides sp. CAG:409 TaxID=1262913 RepID=R7J5J6_9BACT ---DLGARLKETLAGKAATVGVAVI-FNGNELV-TVNNMYRYPMMSTFKFHQALSVLDYLN -KNEKDLNTEILVKQSQLLAHSPMRDANPKGNMSVGDLLKYTLIDSDNNACDVLFDLIGGP -KVTEKYIHKLGIEDVAISQTESLMHANPDNCMLNWCKPSSAVLLLETFLQQPICNKSQKL -FIQRAMADCSTGKDKLKAGLPKDVLLAHKTGSSDRNADNDMGFVVLPNGQYYTIAVFVMN -SRESDKKNARIIADVSRVVYEYf ->[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A552L7C6_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVMASGSGDMQYLGANKYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Chlorogloea sp. CCALA 695 TaxID=2107693 RepID=A0A2T1ECA8_9CHRO -----KTAVQQLGKNKGLTPGAFFIDLDTHNYL-DWNGSLPFAAASTIKVPVLVAFFQDVD -AGKIRLDEKLTLQKKLIGSGSGGMQYPLGTKFTALNTATQMIVISDNTATNMLIDRMGGI -AKLNERFQSWGLVSTKINNPLPDLTGT------NITTPKDMGELMSLVDRGELMSLRSRD -RLLEIMRRTKT-RTLLPPGLGEGAIIAHKTGDIGS-MVGDVGLVDMPNGKRYIAVAMVKR -PHND-SRAQELIRQISRTTYQHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 2B10 TaxID=2483355 RepID=UPI000F7AFF0B ---ALAAAINALGGGFQGKVSIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTMMNAID -EGRYALTAPVTITRSDLTLHQPIAYLMKDGATTVGDLLRRALTMSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLTPQSTQ -WLLDTMSHTRTGRARIRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKAYAVAVMIGD -TARPVPERQQLIQTVVSSIV--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9XQV0_9BACT --qKLETSISNIDNTLDGVMGVAILDLTGGQKF-LLHADDVFPQASSIKIAVLAELYHQAQ -QGKLKLADLYTMQQSDLVPDSDIMGGLTPAIITLRDLATMMVAVSDNSATNVLIDRL-GM -ENVNALMDSLGLPHTRLRRKMMDLKAA-SEGRENISTPREMMTLLESIYRGKVFNKEMTD -DFFKMLSTHK--DSFIPRELPDGLKIANKPGELE-AVRNDSGIVFAQNR-PYVICVMTTY -LHR-ERDGEAAITKISAEAFSMf ->[subseq from] serine hydrolase n=1 Tax=Cronobacter turicensis TaxID=413502 RepID=UPI00131A485A ------------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPEQNEAIPNDERDTTMPVAMAT----------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Alistipes sp. CHKCI003 TaxID=1780376 RepID=A0A143XT01_9BACT ---RLERRIDRIAERCDARIGVAVTT-PAGLLL--SRNDTLLPMLSVFKFPVALAALDRME -RDTLPLTHPVTVGFERLDRYSPMRDSLPAGGVALGALLRYAVSASDNIACDLLIDFAGGP -AAVDDYVRSLGIDGMRILTDERRMHLTVGNQRLNAARPSAVCALFDRFLRGGVLSAAHEA -FLRSLLVSTETGADKLKAGLPARTVIGHKTGSSDRTADNDAGYVLLPDGRSYCIAVFVTD -SEEDDAANAAVIAAISAAVYDHf ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9717 TaxID=1160286 RepID=I4FL98_MICAE ---SLNQKLQALAVKYKLKAGALFIDLDNGAYA-NFREDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=A0A2I9CHN6_MICAE ---SLNQKLQALAVKYKLQTGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas insulae TaxID=424800 RepID=UPI0013D44567 ---QLTTAIDTLARTFDGKFGIAIRAVDEGWTIaSPGARTRMPQQSVSKLWVAMTLMDLRD -QGKARLDDPVLVRPEDLTLHQPIAMLVKGAGTTVGELLTRALTHSDNTANDRLLTYVGGP -MAVRAMIERKQLGDIRFGPGERLLQSAYVNDPPDGAAPLAIADAIARLARGELFTETSTR -ILLDTMGASVTGRARLRAALPAGWKIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -SRRPIRERQQLIQSVAAAVADY- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa EAWAG127a TaxID=2529855 RepID=A0A5J5LUS1_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETASKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf67 TaxID=1736230 RepID=A0A0Q4Q247_9SPHN ---ALVATINALGGGFQGRVGIAVRSIDEGWVV-GHAMDQRMPQQSVSKLWVALTTMNAID -EGKLALATPVTITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLRHGMLLTPQSTS -WLLDTMSHTRTGRARLRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TARPVQERQQLIQTVVSAIVA-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus centrosporus TaxID=54910 RepID=UPI000F0A4441 ---SLQKKLESVLSETSATFGVTVKHLDTNEEA-RINSDQYFQMASTFKVPILATLFRDVV -EGRLSLETRIRLTEDDLVSGSGVLKEFLPGAVAVKDLATLMIIVSDNLGTDKVLELV-GI -ERVDAFMKELGLAHISIQNSCWDLLSFQATLENNVSTPDDMCQLLALIASGELVSQEACD -GILDVMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFAIAAFSHG -N-ESMKAGERIIAQLTRTAYDHf ->[subseq from] Putative beta-lactamase n=1 Tax=Planktothrix agardhii NIES-204 TaxID=282423 RepID=A0A2Z6CDH0_PLAAG ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRQISSTIYQYf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7PID6_9BACT ---RLTDLLQPVIAAHQGAVAVSVKHLKTGATF-AHRADEPMPTASLVKFPVMVAAYQQAA -DGMLDLAKSVVLKEEDKVPGSGILTKHFSAGLSVRDAIRLMIAYSDNTATNLVVDQI-GL -AATTDLMTKWDFPHTRLHAKVYRGDTSIAPDRSGSTTAGEMLRLLERLHRKELVSEEASQ -QMIDHLLACDD-KQRLAKFLPAGTKVALKTGSVS-ASRTVAGIIESPSG-SIAVCVLTEN -NKIDDNAAQLLSAEIARQLWQHf ->[subseq from] serine hydrolase n=1 Tax=Zavarzinella formosa TaxID=360055 RepID=UPI0002E82AA0 ----LEQKISALAKAHEGRVSVAVKHLGTGETI-LLNSGEVMTTASLIKFPIMAEAYAQEL -AGKVKLDQKITLTKEDMVPGSGILTEHFSPGMSLRDAIRLMIVYSDNTATNLVLDQV-GI -KAVNDRMAAMGCGETRINAKVFKGSTRTKQYGLGSTTAKDMVSLLELLHREELVSPAASK -AMLAHLKKCED-KDKFPRRLPPSVVVAHKTGSVNE-ARTDAGILYFPGG-PVAVCVLTNQ -NKTPDNAGNKLCADIALAVFEHy ->[subseq from] Beta-lactamase n=3 Tax=Alphaproteobacteria TaxID=28211 RepID=A0A2T5GSJ5_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLAALGGP -VAIQRWLSSQNIPGIRMDRSIAQLLRGHLADIKDVATPIAMVTLLNKLDNGTVLTPQSRA -FLLGLMGRCATGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVARVIYNRf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas glacialis TaxID=658225 RepID=A0A502G4J0_9SPHN ------------------------------------------------------------- -----------------------------------AKVLELMIVRSDNQAADQLLAAVGGP -VTVQQWLSSHAITGIRVDRTIAQLLRGHLADSKDVATPTAMVALLYKLTNGTVLTPQSSA -YLFDLMRRCQTGTRRIRALLPTGTLVEDKTGTLD-GVTNDVGFITMPDGHRVAVAVFARG -GR----DRQPGIAAVARVIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa 11-30S32 TaxID=2358142 RepID=A0A510PNI5_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVMASGSGDMQYLGANKYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014482306 ------NSLQTLTANADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD -AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVSMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_AC_P_19900807_S299 TaxID=2486264 RepID=A0A552AHI4_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] AmpC n=1 Tax=Planktothrix agardhii NIVA-CYA 126/8 TaxID=388467 RepID=A0A073CD29_PLAAG ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRKISSTIYQYf ->[subseq from] Beta-lactamase class A n=1 Tax=Synechococcus sp. PCC 7502 TaxID=1173263 RepID=K9SNY9_9SYNE ---ELTTKINALTKSQDITVETYLTDLDSGGYV-NIKGSEAIASASMIKIPVLVAFLQDVD -AGKARLDEQLVLSKDVIVGESGGLQEPVGTKISALETITLMIIISDNTATNMIIKRIGGI -EEANQRFLSWDLTSTVIRNPLPDLTGT------NTTSPEDLVNLLSMVEQGKILSPRSRD -RLMDIMHRTKT-NTLLPQGIPPDARIAHKTGDIKS-VVGDAGIIDMPNGKRYIISAIAKR -PSND-QRANELIRQISRTVYTH- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteriales bacterium 13_1_40CM_3_55_5 TaxID=1803468 RepID=A0A1Q7MRI0_9BACT --qKLESTINDIDRSLDGVIGVAILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQAQ -TGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -ENVDGLMTSLGLTRTRLRRKMMDLKAA-SEGRENISTPGEMMILLENLYRGKVLNKEMTE -DFFKVLSTHKS--SFIPRELPEGLKIANKPGELER-VGNDSGVVFAEKR-PYVICVMTTY -LQR-ERDGEEAISRISLAAYRTf ->[subseq from] Putative beta-lactamase n=2 Tax=Parabacteroides johnsonii TaxID=387661 RepID=B7BBD2_9BACT -------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD -REHIPLDSTVCITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI -KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA -FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN -SLESDETNARIMADITRVIYH-- ->[subseq from] Beta-lactamase OXY-2 (Penicillinase) n=2 Tax=Xenorhabdus nematophila TaxID=628 RepID=D3VGM9_XENNA ------------------------------------------------------------- --------------------------------MTLGELSAATLQYSDNAAMNLILNQLGGP -HEVTKFARTLGDNSFRLDRKEPELNNVIPGDERDTSTPRAMADDLYHLALGNALDATQRE -QLITWLKGNTTGAASIRAGVPEGWIVGDKTGRCDYGSTNDIAVIWPVNQPPLILVTYFTQ -PDKEASARPDVLAAAARIMTQH- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I3SF15_9BACL ---SLQKKLESVLSETSAAFGVTVKHLDTNEEA-RINSDQYFQMASTFKVPILATLFRDVV -EGRLSLETRIRLTEDDLVSGSGVLKEFLPGAVAVKDLATLMIIVSDNLGTDKVLELV-GI -ERVDAFMKELGLAHISIQNSCWDLLSFQPTLENNVSTPDDMCKLLALIASGELVSQEACD -GILDVMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFAIAAFSHG -N-ESMKAGERIIAQLTRTAYDHf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa FACHB-524 TaxID=2486203 RepID=A0A3N0WE73_MICAE ---SLNQKLQALAVKYKLQTGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=2 Tax=unclassified Calothrix TaxID=2619626 RepID=A0A2H2XV80_9CYAN ----LKSAIQSLAANNNLTPGVFAADLENGSYV-DFNGGAMFSSASTIKLPILIAFFQDVD -EGKIDLSETLSTSKSTIVGGSGDMQNRPGTKYNILEVATKMMIISDNTATNMLIERLGGV -EKLNQRFRNWGLNTTSLRNTLPDIPGT------NTTSPKELGSLMAMITKGNIVSQESRG -RILEIMRGTFK-DTLLPVGLGQGATIAHKTGEIGS-LLADAGLVDLPSGKRYIVAVMVQR -PRND-VSAEKLINGISRVVYQQf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa Sj TaxID=1979544 RepID=A0A2Z6UQ53_MICAE ---SLNQKLQTLAVKYKLQAGALFIDLDNGAYA-NFRGDTVFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. YJ09 TaxID=1104779 RepID=UPI0012D2BE1F ------------------------------------------------------------- -------------------------------GVPVRTLMAKMLIHSDNHAADVLFKDVGGP -RAVHHWLVQNGIHGVRVDRTIAQLLAAKRWDVRDSSTPKAMVELLRRIYRGELISAQSRN -YLLAEMAKCQTGRNRMKWLLPEGTPVEHKTGTLN-GLTDDVGFITMPDGHRIAVAIFARG -GS----NRPRTIAQAARAIYDGf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis panniformis Mp_MB_F_20051200_S9 TaxID=2486223 RepID=A0A552Q431_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=A0A552BS55_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Genome sequencing data, contig C307 n=3 Tax=Microcystis aeruginosa TaxID=1126 RepID=I4GIX2_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI000468934F ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis sp. Msp_OC_L_20101000_S702 TaxID=2486218 RepID=A0A552CC34_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. B3706 TaxID=2656760 RepID=UPI001407567D --kSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -NNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT -KMTDLYLRTLGSKNFSIQATEEEMNKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD -FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARIIADISQVVYNFy ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9807 TaxID=1160283 RepID=I4H0J5_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_B_20070730_S2 TaxID=2486256 RepID=A0A552D6B0_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9XSH6_9BACT --qKLESKIEQVDRNLDGVMGVAIEDLTTGDHY-FLREDEVFAQASSIKITVLANLYLQAQ -QGKLKLTDLYTVQSSDLVPDSDIMNGLTPGIVTLRDLATMMVAVSDNSATNVLIDRV-GM -QNVNAMLDSLGLSHTRLRRKMMDLEAA-KQGRENISTPREMMTLLDAIYHGKLLNKESTE -DFFKMLSTNKQ--SFIPRDLPPDLKVANKPGELE-AVRNDSGIVFVAGR-PYVICVMTGF -LR-NEREGEEAITKVSLETWRMf ->[subseq from] hypothetical protein n=1 Tax=Planktothrix TaxID=54304 RepID=UPI00041C7362 ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRKISSTIYQYf ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa PCC 9809 TaxID=1160285 RepID=I4HZ79_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Porphyrobacter neustonensis TaxID=1112 RepID=A0A192D2A8_9SPHN ---SFEQRIAQLANPALGRIGVAAIDLATGEEV-MVLGDQLFPMASTSKVAVAATFLEMVE -KGRFSLSSEFPLLLPVASAYSSAKAPVRAGQLPAIDLIEMMITRSSNPATDALLAAVGGP -GVVNDWIRRQGISNFSINRDIATLVRATFIDPRDAATPRTMAKLLAGIYGGQYLSDDSRR -VLLGAMSRTVTGKRRIPAHIPLDARVSHKTGSLNN-TSSDIGLIECPDGRVIAVAIYVTG -QG-TKAAREERIAAIARALYDGf ->[subseq from] Class A beta-lactamase n=1 Tax=Alistipes putredinis TaxID=28117 RepID=A0A1Q6FD30_9BACT ---DLSYRLKKVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLD -RNGLTPDTEIFIPEEELVPYSPLRKEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP -AATDRYVRSLGLCNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQILTPTLRE -MILQNLINCKTGADRLPKPLSTGAVIGHKTGTSNRDGTNDLGFVILPDDTRYTIAVFIKD -SAENPETNARIIADISETVYRY- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter arachoides TaxID=1850444 RepID=UPI001038F7E0 ---ELTALLGTIASDFGGTMGIAVVDVDSGWTT-GINDRKMLPQQSVSKLWVALTALDQVD -RGRLTLGKRVVIEPEDLTVHQPLREQVLRTGTDPLDLLTRALTRSDNTANDALLWTVGGP -DAVRAMLREKAIANVRFGPGERLLQSSYLADPVDGATPRAIATALARLARGDLLSPASTE -RMIAILRETHSGPRRLKGGVGTGWSIAHKTGTGQYYGYNDVALLFAPDGRAYAVAVMIGE -TRKGVPQSMAMMQAVTRAVED-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas wittichii TaxID=160791 RepID=UPI0004AA3996 ---ALDAAIDRLGRRFPGDVGLAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDEVD -SGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP -DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA -KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TGRPLAERMKLMQSVVAATI--- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter sp. (strain K31) TaxID=366602 RepID=B0T712_CAUSK ---TMTVQFQEIANRVPGSLGVAVEDLSTGQII-SFNGEKRFPLQGVFTAPLGAAVLAEVE -AGRLRLNETLRIEDVDLSPHSPIADAWPSRDYTVQELLERAVGDSDNTAADVLMKRIGGP -GAVTAWLQGRKVAPLDIDRYERQLQPAYLADPRDTATPLGALRFLEAMNQAELLGPDSRR -LLGGIVSQASSGPNRLRAALPDGARLAHKAGTARTDVVNDIGVYTLKDDRKFAVVVFVSG -SRLSVAEQEKAIADVGRVVMK-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas wittichii TaxID=160791 RepID=UPI00037C5852 ---ALDAAIDRLGRRFPGDVGLAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDEVD -SGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGNDLMVRALTQSDNSANDRLLHQVGGP -DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA -KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TGRPLAERMKLMQSVVAATI--- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DE02838 ---ALQQRLEKLATGKDARIGICALD-QAGTSV-CVRGDERFSLQSVVKLIAGAATLDAAD -HGAVNIEDPIIIRSENLSLKQPLAKIVERNGTNAGDLVRRAIVESDSAAVDILINRLGGT -GKINSFLAGKAISGIRIDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLISTSSTD -RLLAIMNETSTFPDRLRAGVGNDWSVAHKTGTSPNVATNDVGILTAPDGGKVAISVFVAD -SRETPTRRATIIASAAQAVTEAy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9V0Z9_9BACT --qKLENSIAEVDRNLDGAMGVAILDLTDGHKY-LLHANDVFAQASSIKICVLAELYRQAQ -QGKLKLTDVYTVNASDLVQDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRI-GM -ENVNTMLDSLGLTHTRLRRKMMDLKAA-AEGRENVSTPAEMMVLLESLYRGKVLNKEMTD -DFFKVLATHK--DSWIPRDLPDDLRIADKPGALE-GVRNDSGVIFVEKR-PYVLCVMTTY -LRR-ERDGEDAISKVSLVAWRMf ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis aeruginosa NIES-87 TaxID=449440 RepID=A0A2H6L070_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Planktothrix rubescens TaxID=59512 RepID=A0A1J1L5F7_PLARU ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLLGVLVER -EA-DDPQANELIRQISSTIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. D43FB TaxID=2017595 RepID=A0A2A3N0L7_9SPHN ---RLIAQFQRFATLTDGTVGITVRDLTSGESL-SLNGDTLFPMASAYKVAVAGKIFAMID -AGQLALTDIVPRDVATMGP---------GAPLPVARLLDLMLTQSDNEATDMLVARAGGP -TAVNGWVAGLGIKGLRVDSNTADLLYAFARDPRDSATPTAMTDLVAAIRTGRALSPASTH -AFITIMERCRTGKARLPGMLPPGTTIAHKTGTIN-GTGNDTGVITLPDGRMFAITVFVMQ -DHRGRVMRDRIMAEAARAAYDYf ->[subseq from] Putative beta-lactamase n=1 Tax=Erythrobacter sp. SD-21 TaxID=161528 RepID=A5P823_9SPHN --tALQAELQDIGEGFDGVVGIAVTEADSLATM-SYNGSAPMPQQSVSKLWVTMTALDRVD -EGALDLSERVTIGREDLTVYQPIRNIVKARGTDYGDLMDRAITQSDNTANDRLLRYVGGV -QAVEGFLRRNAIEGVQFGADERTKQSAYLDNPMDGATAEGLARALARLARGDLLSENSTQ -LLLETMSRTKSGPRRLKGGVPAGWEFGHKTGTGQQSGYNDVGILTAPDGTRYALAVLIGQ -TRASYAARMAMMQEVTQRVVRY- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8CZS6_9BACL ---NLQQKLESVLSESSGTFGVAVKHMGTGEEA-QIRAEQYFQMASTFKVPILAALFRDAD -AGLVSLEQRYRLSEADLVPGSGVLKEFLPGAVALKDLATLMIIVSDNLATDKVLEII-GK -ERVEAYMRELGLTQISIKHDCWELLSFQASPENNVATPADMGRLLELIGTGKLASEQASD -GVLDIMKRQQL-RNRIPYLLPDETIIACKSGTVGH-VVNDVGIVYLSDKGAFAIAVLSSG -NP-SVKEGERVIARLAQTAYEHf ->[subseq from] hypothetical protein n=1 Tax=Planktothrix agardhii TaxID=1160 RepID=UPI0004123AC8 ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLLGVLVER -EA-DDPQANELIRKISSTIYQYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-4325 TaxID=2569534 RepID=A0A5J4F560_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Class A beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W5MZV5_9BACT ----------------NVNVGIATL--KDKDLV--VVNNKKYPLLSVFKYFVAIKVLKYID -QKHISLDTKITINQNDMQTHSPMIKDYKNYPITLAQLLEYMISQSDNNACDILIDYSGGI -NELEKFIHELGFNDISIKVNEKDMNSDIYNQYLNTSTPKDIVLMMKRVKDNNILSSSSFA -FLENIMLKTSTGENKSKAGLPKNTKIYHKTGSGSRTADNDAGYVRLPNGDLYYIAIMIKD -SPLSDDENSKIISDISKIVYQYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas montana TaxID=1843236 RepID=UPI0009F9E97A ---ALAATVERLGRGFDGIVGIAVRDVQAGWYI-SFNGQGYFPQQSVSKLWVALTVFDAID -RRRMSLSDTVRIERKDLVVHQPLRAKVGPNGASVSELLLAAMTTSDNLANDSLLRTVGGP -GAVRAFLDRAQLDGIRFGPGERLLQAKYLADPIDGAQPEKVALALARLRKGDLLSPESTQ -RLLTLMASSRTGPQRMRAGSGPGWAFAHKTGTGQATGYNDIGLMTSPDGRTYALAVMIKS -TRQPIPVRQRLMANVARAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. PAMC 26605 TaxID=1112214 RepID=UPI00026CAC4C ------------------------------------------------------------- ---------------------------------SAAKVLELMIVRSDNHAADQVLAALGGP -VAVQQWLSSHNIVGIRVDRTIDQLLRGHLADSKDVATPVAMVALLHKLDSGAVLSAQSRA -FLFELMRRCETGTRRIRAMLPAGTPVEDKTGTLD-GVTNDVGFITMPDGHRVAVAVFARG -GR----DRQPVIAAAARVIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Legionella sp. TaxID=459 RepID=A0A522FDW4_9GAMM --kDLLRKISSIEKNSKVIIGVSAILIEKNKMI-THNGTKRFFMASTIKLPIAIAFLHRVD -EKKDSLNRSMTLDFKNSVPGSGSLYHTFERRVSMQRILKLMMIESDNSASDALLHAAKGP -VYVTKRMGEIGFKNVIINRSILQILMRFEKDIRDTITPNDMALLLVKLFKGQILSEESTN -LLIHIMEQCRTGRHRIKGLLPHYVKVAHKTGTWGYRFASDVGIITLPNKGHIAIAIYVKS -QSASDYPRNRAIALTSRAIYDHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium japonicum BiD32 TaxID=1301087 RepID=N1MM32_9SPHN ------SVVRNLGQSFRGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRLTDTTTITRNDLTLHQPSAAMLKDGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKQGDMLSATSSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A552AL94_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWC2_61_19 TaxID=1797932 RepID=A0A1F9SQN2_9BACT ------GGLEKVSDAYRGRVGIYIKDLHTGKVW-EYNADRLFPSASLVKVPIMVSVLDKIK -LGTITLDTQIRLTRRERVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATRMLIDYV-GM -DYLEDNFKRLGLVETNICQEGMSLTSG-RLKKDNYTTAREMAGLMEKIYDGEMVNREASE -FMLDVLKHNKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-FVLAVLTTE -VP-DYTSAKNFITKVAKLTYAYy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Odoribacter sp. AF21-41 TaxID=2293111 RepID=A0A373UK51_9BACT --kELEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVADYCE -KKGLSFDTPIYIRKADLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFQQTGGT -EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG -FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD -SEESEAATARIIADISKTVYRH- ->[subseq from] Uncharacterized protein n=1 Tax=Oscillatoriales cyanobacterium CG2_30_40_61 TaxID=1805291 RepID=A0A1J5GY69_9CYAN ----LKTAILGLAKDSKLKPGVFLVDLDTGNYV-DVQGQEAVPAASTIKVPILVSFFQAVD -EGRVRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETANLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMHNLLPDLEGT------NKTSAKDLVNLMADINQGKLVSLKSRD -FMLRIMQETRN-RSLLPSGLGEGAFIAHKTGNIDS-VCGDIGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRQISSTIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingopyxis sp. TaxID=1908224 RepID=A0A2G2D3V4_9SPHN ---ALVREIQELWRAFPGKTGIAVKRIDGAWEF-GFRLDEYFPQQSVSKLWVAMTMLDKID -QGKASLSDPIRIGKEDLTLHQPMAVEVERNGKTVYTLLEMALASSDNTANDALLRHAGGP -EAVRRFIDKNSLGKIRFGPGERLLQSAYLADPVDGASPLAIAGALDKLARGELLSDNSTK -LLQSILKRTRSGPNRLKAGVPAGWEFLHKTGTGQSTGYNDVGIMTAPDGTRYAVVVMLGD -TTASIPARMRLMQSVTRAVGR-- ->[subseq from] Uncharacterized protein n=2 Tax=Microcystis aeruginosa TaxID=1126 RepID=L7EBB6_MICAE ---SLNQKLQALTVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLKGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Merismopedia glauca CCAP 1448/3 TaxID=1296344 RepID=A0A2T1BZC0_9CYAN ----LETQIKTLAAKYQLYPEVFLVDLDSGNYV-NLAGDTAISAASTIKVPVLVALLQDVD -AGKVRLNEELTLTSKVIGSGSGAIQQKIGSKFTVLEVATKMIVISDNTATNMIIERLGGQ -EKLNSRFQSWGLTTTAIKNPLPDLEGT------NTTSPKDLVEVMAMVNRGELVSMRSRD -RMLGIMRQTVT-NTLLPQGLGKGSTIAHKTGDIGS-VVGDVGLIDMPSGKRYLAAVLVKR -PH-NNPKAQELIRQISRATYNHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Apibacter TaxID=2630820 RepID=UPI00132AD745 --qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -KNLLSLESNIYLKKSDIKKYSPLAKEHPEGNIPIGDLLNYTVSKSDNNASDALYYYMNGT -KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD -FLFQALTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARMIADISQVVYNFy ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_SC_T_19800800_S464 TaxID=2486257 RepID=A0A552E248_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0014241406 --kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPIFIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMVIDRLGGA -TKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium faniae TaxID=570446 RepID=A0A1G4T6G1_9SPHN ---RLLAQFESFAALTDGTVGIAVQDLSTGEEQ-SLNGDMLFPMASTYKVAVAGKILSMAD -AGVLGLQDQVPLDPA-----------QPARTRSIHDLIDLMLTHSDNDATDALVARAGGP -AVIDDWVGALGVKGLRVDSNTAHLLYAFTRDPRDTSTPRAMNALLAAIRLGQALKPASTA -YLLEMMERCHTGKARLKAMLPPGARIAHKTGSLN-GYGGDVGIVTLPDGRMFAISVFVMK -DYKGRTTRDSIMAHAARAAYDYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Y57 TaxID=334801 RepID=UPI00063F5BFD ----LDGAIERLGRRFPGDVGLAVRDIQTGWTS-HHRGLDYFPQQSVSKLWVSLAALDQVD -GGTLDLSRPLTVRAKDLTLHQPIRALALRPGTTGEDLMIRALTQSDNSANDRLLKEIGGP -DAVRAALRGKAIAGIRFGPGEPRLQAQYLANPIDGATPIAMVDTLARLRRGELLSPASTA -KMTGIMEETRTGALRLKAGLRPGWRLAHKTGTGQQAGYNDVGILTSPDGRSYAVAVMIGR -TSRPLAERMKLMQSVVAATI--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. 66-54 TaxID=1895845 RepID=A0A1M3PTT3_9SPHN -----VSIIETLGRNFNGSVGIAVQRVDAGWTI-AHNGNKLFPQQSVSKLWVAMTMLDAVD -RGKITLDTPVMIRPADLTLHQPIAAMVKGSGTSLRDLFYRAMTQSDNTANDSVLRTVGGP -DAVRGYLARFGPDTIRFGPGERLLQSAYLANPIDGASPLAIVHALAKLKKGDMLSPASTQ -LLLSTMSEAKTGPQRIKAGVPAGWSYLHKTGTGQSTGYNDVGIMTAPDGTSYAIAVMIGE -TTLAIPQRWELMQSVARSVA--- ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=K9PGH4_9CYAN ----LEPQIKTLMAKYSLQTGMFFLDLETGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEQLTMRSDLVTNGSGIMQERVGKKYTALETVNKMITISDNTATNMIIDRLGGA -AKLNQRFRGWGLKDTVIRRLLADLRGT------NTTSSQDLARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-IIGDAGFITMPNGKHYLAAIFVKR -PYRD-SRGRDFIRQVSQLVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HI0063 TaxID=1822240 RepID=A0A165R5D5_9SPHN ---AFEQELEEIAASLDGTVGVAVTDVETGRSY-AIRGDDWFPQQSVSKLWVALTALDEVD -EGRLELDEAVAIGPKDLTLHQPIRDLVQARGTDYADLMQRALTGSDNTANDRILRRVGGA -EAVEDFLAAKKITGVRFGADERTKQSGYLADPIDGATPVGITEALARLARGELLSPSSTA -LILATLQNTRSGPQRLKGGVPPGWSIGHKTGTGQQSGYNDIGILTSPEGHRYTLAVLIAR -TREPTLARMRMMQEVTRATAQ-- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A2D7ZJV9_9CAUL ----LASQIAALGAAFDGRAGIAVRDLEGGWTA-THDGEALYPQQSVSKLWVAVSVLDAVD -RGVLSLDDPVLVRREDLSIHQPIRDHVGRNGTTVGELLASATTRSDNAANDVLMRLVGGP -DHVRAVISARELGAISLADEERYFQTAYLEAPPDGASPVAMVEALDRLAAGELLSSTSTA -HLLDLMAQSRTGPERLAGGLVEGWSLAHKTGTGQATGYNDVGLLTAPDGRTYAVAVFIAD -TTRSVPERQALMQAVTRAVIAQ- ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI001107B05F --kALEPEVKALMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLEEKLTMRRDLVTNGSGTMQERVGNKYTALETISKMITISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSLQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPSGKRYLAAIFVTR -PYKD-SRGRDFIRQVSRLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Microcystis panniformis FACHB-1757 TaxID=1638788 RepID=A0A0K1S6K4_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFREDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Uncharacterized protein n=3 Tax=Microcystis aeruginosa TaxID=1126 RepID=L8NMA8_MICAE ---SLNQKLQALTVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3SQG0_BRECH ---SLQEKLEAVLSESSATFGVVVKHLETQEEA-QINSNDYFQMASTFKVPILATLFRDVS -EGRLSLEQRIRLTEDDLVPGSGVLQEFLPGAVAVKDLAMLMIIVSDNLGTDKVLELV-GT -ERVEAFMKELGLAHISIRNSCWELLSFQPIPENNVATPADMGKLLELIATGQLVSQEACD -SILDIMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFTIAAFSHG -NH-STKEGERMIARLTLTAYEHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V572_9BACT -------------------------------------------------VMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVAAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIRAGLPKSWVV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas paucimobilis TaxID=13689 RepID=A0A031JGZ0_SPHPI ------SVIRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLTDTTTITRKDLTLHQPTAALVGSSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGFLARRTIKDIRFGPGERLLQSNYLANPPDGAAPSSIVKALAKLKEGEMLSPASSQ -LLMSIMSQAKTGPQRIKGGVPAGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=UPI0005C3F8E8 ---SLVNQLDGLIRNFDGVAGIAVTSVESGWIA-TANAQRRMPQQSVSKLWVSMTVLDAVD -RGKIRLDDPLTITKSDFTLHQPVASLVKGDTATVGEIVRRAMQMSDNTCNDKLLRLVGGP -QAVRDFIARKGLGAIRFGPGEKLLQASYVKDPPDGAAPEAIASALGRLKRGELLSPTSTD -WLLRTMAGAKTGKARVRGAVPAGWDYAHKTGTGQTAGFNDVGILTAPDGRSYALAVMIGD -TPRPVRERQLLMQAVASAIVA-- ->[subseq from] Penicillin-binding protein transpeptidase n=2 Tax=Crinalium TaxID=241421 RepID=K9VW32_9CYAN -----KPQLEALATANKLQAGVFVLDLDTGAYL-DYNSSSTFSAASTIKVPVLVAFFQDVD -AGKVSLDEMLTMEPEMIAKGSGDMQYQKAGKFTALETATKMIAISDNTATNMLITRLGGA -EALNQRFRSWGLVATTINKPLPDLEGN------NSTSPQELANVMVMVNEGRLVSVRSRD -RILDIMRQTVT-KTLLPPGLGKGATIAHKTGDIGS-ILADVGLIDMPIGKRYVASVMVQR -PHND-VAARKLIQQISRLTYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. HKS19 TaxID=1813879 RepID=A0A5B8LMD6_9SPHN -------LVQMLTRDFGGKVGIAVKSLDEDWTV-ESNGDIKLPQQSVSKLWVAMTVLDARD -AGKLSLDDPITVKKEDLTLNQPIAALVKDAGTTVGELLQRAMTQSDNTANDRLLQYVGGP -TVVRAFLAKKAIADIRFGPGERALQSRYIADPPDGAAPRAIATALARLKRGELLSPNSTQ -YLIGTMESSRTGKLRMRGAVPEGWTFGHKTGTGQTAGYNDVGFLVSPTGKTFTIAVMIGD -TNKTIPERQALMQAVVLGVVT-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HI0028 TaxID=1822227 RepID=A0A176E1N6_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa KW TaxID=1960155 RepID=A0A1V4BL59_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETASKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc carneum TaxID=374162 RepID=UPI000BBBA474 --kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Planktothrix agardhii TaxID=1160 RepID=A0A1J1JGN3_PLAAG ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINRGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGDGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLVGVLVQR -EA-DDPQANELIRKISSTIYQYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=U3N7T6_KLEPN -------------------------------------------LCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAG----------------------------------------- ------------------------ ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-2520 TaxID=2303982 RepID=A0A5A5REI9_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVMASGSGIQYLGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Nostoc carneum NIES-2107 TaxID=1973483 RepID=A0A1Z4HKW3_9NOSO --kALEPQIKALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPSSKE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKHYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter citreus TaxID=225971 RepID=UPI001321FE58 ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas histidinilytica TaxID=439228 RepID=A0A1T5GGI9_9SPHN ----LDAAIDRLGHRFPGDVGIAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDQVD -SGRLDLSRALTVTARDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP -DAVRATLRGKAIAGIRFGPGEPRLQAEYLANPVDGATPIAMVDTLARLRRGDLLSPASTA -KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TNRPLAERMKLMRSVVAATI--- ->[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A551Z0E9_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNRRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. C8-2 TaxID=2492837 RepID=A0A5B9YLE4_9SPHN ----LDAAIDRLGHRFPGDVGIAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDQVD -SGRLDLSRALTVTARDLTLHQPIRTLALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP -DAVRATLRGKAIAGIRFGPGEPRLQAEYLANPVDGATPIAMVDTLARLRRGDLLSPASTA -KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TNRPLAERMKLMRSVVAATI--- ->[subseq from] serine hydrolase n=1 Tax=Xenococcus sp. PCC 7305 TaxID=102125 RepID=UPI0011817DEA ---KLKDKLSSLTANYQLEAGVYIVDLDNKNYV-NFNGSQAYSAASTIKIPVLVAFFEDVD -AGKIRLDEKLVVTKEVIGGGSGYMQKEIGTKYSALHTATDMIRVSDNTATNMLIQRLGGM -EVLNQRFAEWGLNNTAIRNPLPDLTGT------NTTSPVDLGNLLIKINRGDLISLRSRD -RLLAIMRTTKT-RTLLPQGIEKDAVIAHKTGDIRS-SLGDAGIVDMPNGKRYIVSVLVKR -PAN-DPQAKILIQKISQTTYQH- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis sp. M_QC_C_20170808_M9Col TaxID=2486217 RepID=A0A551YUP1_9CHRO ---SLNRKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVMASGSGDMQYLGANKYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8D553_9BACL ---SLQKKLESVLSETSATFGVTVEHLDTKEEA-RINSDQYFQMASTFKVPILATLFRDVV -EGRLSLATRIRLTEDDLVSGSGVLKEFLPGAVAVKDLATLMIIVSDNLGTDKVLELV-GI -ERVDAFMKELGLAHISIQNSCWDLLSFQPTLENNVSTPDDMCKLLALIASGELVSQEACD -GILDVMKRQQL-RNRIPYLLPDKTIIACKSGTIGS-VVNDVGIVYLPEGGAFAIAAFSHG -N-ESMKAGERIIAQLTRTAYDHf ->[subseq from] class A beta-lactamase n=1 Tax=Parabacteroides johnsonii TaxID=387661 RepID=UPI0011DD6B14 -------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD -REHIPLDSTVCITREQMHEYSPLRNKYPNQGISLRDIITYTITYSDNNTCDWLIDFAGGI -KKVGTFIKSLGIEKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA -FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN -SLESDETNARIMADITRVIYH-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0013D0D36A --kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPIFIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMVIDRLGGA -TKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium japonicum BiD32 TaxID=1301087 RepID=N1MKN2_9SPHN ----LIAQFQRFASLTDGTVGIVVRDLATGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD -AGALTLEERLA---------------SPAGPVPVATLLDLMLTRSDNGATDLLVARAGGP -AAVHHWVAGLGIRGLRVDSNTADLLWAFAQDPRDTATPTAMTDLVAAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVITLPDGRLFAITVFVMQ -DHKGQATRDRIMAEAARATYDYf ->[subseq from] Beta-lactamase n=1 Tax=Microcystis sp. 0824 TaxID=1502726 RepID=A0A2L2XMR6_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides plebeius TaxID=310297 RepID=UPI000E4EF7F5 --qELYTNIHQFISQQKAEVGVAIIA-DGKDTV-TVENNRRYPLMSVFKLHQALAVGNYCK -RHQLSFDTLLTVDSTDLQPYSPLRDRAPHGGFSLKQLMEYTLHLSDNNACDILFKFTGGP -AMTDRYIRSLGVNDFSIQYTEDDMHRNLNLGYENWSSPLATAEVIEALLTRTLFDKPHQE -FIKEALITCQTGTSRIVHPLQKQVTVGHKTGTGDRNAINDAGFVQFPNGHRYTLVVFVKD -SQESMEDTEAIIAQISEMVYQAf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium 28-55-16 TaxID=1970589 RepID=A0A258RNR7_9SPHN ----LENLLQEQWQLFPGRTGVAVMRLDGGEWItGQRMTELFPQQSVSKTWVALTILDLVD -QGKVSLDQKVRITRDDLAVHQPIRDRVIANGVTVLALLEQAIIASDNTANDSLLRTVGGP -QAVQSFLARKNLGAIRFGPGERLLQSRYLANPIDGASPEAIVRALARLARGELLSPASTK -LILGIMSRTSSGPNRMKAGVPTGWRFLHKTGTGQSTGYNDIGIMTAPDGTRYAMAIMMGS -TTASIPQRMSFMQFVSRTVATY- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A352H9A3_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRSGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas virosa TaxID=544645 RepID=A0A412X2A3_9BACT --rELEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVADYCE -KKGLSFDTPIYIRKADLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFQQTGGT -QATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG -FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD -SEESEAATARIIADISKTVYRH- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium vermicomposti TaxID=529005 RepID=UPI00142221B5 -------VVRNLGQSFQGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLTDTTTITRKDLTLHQPSAALVGTSGTTYSDLMRRAMTQSDNTANDTMLRAVGGP -EAVRAFLARRTIKDIRFGPGERLLQANYLANPPDGAAPTSIVKALAKLKEGDMLSPASTQ -LLLSTMSQAKTGPQRIKGGVPAGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTLPIPSRWELMQAVAKAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Luteibacter sp. 22Crub2.1 TaxID=1283288 RepID=A0A1T5DV67_9GAMM ---TLQASLQKLADQAPAKFGIIVVDLDGSASA-KVNDDRAYMLMSTFKAPVSAAVLHQVD -AGKLRLDQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAVTQSDNTAVDALLKLVGGG -QVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK -RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGKRAVVGAFLRD -TTSTDEQRAAWFKELGTVVSK-- ->[subseq from] Beta-lactamase (Penicillin-binding p rotein, transpeptidase) n=1 Tax=Chrysosporum ovalisporum TaxID=75695 RepID=A0A654SIN5_9CYAN -----KDAVQNLATANNLKPGVFFVDLETGGYV-DVNSSISFPAASTIKVPILIAFFQDVD -AGKVRLDEMLTMEKDMVATGSGNLQQQVGTQYSALELATLMSTTSDNTATNMLIARLGGI -QALNQRFQSWGLSATALRNPLPDLTGT------NTTSPKELGNLLAMVNQGNLVTMRSRD -LILDIMRRTER-NHLLPSGLGVEATIHHKTGDIAT-MLGDVGLIDIPTGKRYIAVVMIQR -SNN-DPGAEKLISSISRTAYEQf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8ZZ84_9BACT --qKLEANVQEVDRHLDGVIGVAILDLATGQKY-LLHADEVMPTASSIKIAILAELYRQAQ -QGKVKLTDFYTLEQADLVGGSGISSVLTPGMLTLGDVAGLMISVSDNSATNVIIDRL-GM -ENVNALVDSLGLTHTRLRRKMMDLKAA-AEGRENVATPREMMLLLENLYRGKVLNQQMTE -NFFHLLSVHKE--SYIPRNLPEDLKVANKPGELE-GVRNDCGIVFAGKR-PYVISVMTTY -LKRE-RDGGDAITKISDAAYQMf ->[subseq from] serine hydrolase n=1 Tax=unclassified Erythrobacter TaxID=2633097 RepID=UPI000AC1E242 ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) TaxID=392499 RepID=A5V4D9_SPHWW ---ALDAAIDRLGRHFPGDVGLAVRDVQTGWTS-HHRGLDYFPQQSVSKLWVSLTALDEVD -SGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP -DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA -KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TGRPLAERMKLMQSVVAATI--- ->[subseq from] hypothetical protein n=1 Tax=Planktothrix agardhii TaxID=1160 RepID=UPI0003F9EF16 ----LKTAILGLAKDLKLKPGVFLVDLDTGNYV-DIQGQEAVPAASTIKLPILVSFFQAVD -EGRIRLDEVLTMEEKHVAKGSGELQKPVGSKFTALETADLMITNSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSARDLVNLMADINQGKLVSLKSRD -FMLRIMQQTRN-RSLLPRGLGEGAFIAHKTGNIDS-VSGDVGLIDMPNGKRYLLGVLIER -EA-DDPQANELIRQISSTIYQYf ->[subseq from] Beta-lactamase n=1 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=A0A2Z5FXW8_9BACT ----LQQRIATLAEEAKGIVSVSCSLPRTNLNC-DLNAHGHQPMQSAFKLPLGLAVLHAVE -QGQLSLDQQVRFLPSDIYKFSPLQDMYPNANVPLRQLLELSVGRSDNTATDILLRLMGGT -GPVQSYLDTLGLQGIQIRDSERSLHDDERRQYRNFAEPAAFVKLLRLLADTSPLNAEHAQ -YLLAIMTASPSGPKRLKGLLPAGTIVAHKTGTSGYEATNDVGLITLPDGRRLALAVLVTD -AHADEAAVEHTIASIAHACYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas astaxanthinifaciens TaxID=407019 RepID=UPI000A01D531 ---ELTRRIGTLGASFDGKVGIAVQAVEQGWQT-GWKDKELYPQQSVSKFFVALTAMDAVD -RGRLTLDGPVTLTRDDLTVNQPIAQRVLSGGTTVEALLIDAITKSDNTANDKLMRVAGGP -AAVRRFIADRKLGAIRFYEGERALQSRYISDPYDGAAPAAIVGTLARLKRGELLSPASTA -RLLTIMSDTRTGKNRLRGGLKPGWTLAHKTGTGQQAGYNDIGVLTAPDGRSYAVAVMIKR -TATPLIVRMNLMNEVVRAVIA-- ->[subseq from] Beta-lactamase n=2 Tax=Nostocales TaxID=1161 RepID=A0A0D6KGJ8_9CYAN --kALEPQIQALMSRYSLTTGMFFLDLDTGNYL-DIKGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGDMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNNKLVSPGSKE -QALDILRHTTV-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR -PYKD-TRGRDFIRQVSQLVYNY- ->[subseq from] Beta-lactamase n=1 Tax=Microcystis aeruginosa (strain NIES-88) TaxID=449441 RepID=A0A139GH62_MICA8 ---SLNRKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139X3L3_9CYAN -----KSAVQSLAASNNLTPGVFLIDLDNGGYV-DLNGAASFAAASTIKIPILVAFFQDVD -AQKIRLDESLTLESGMVAGGSGNMQKPVGTQFTALEVATKMMTVSDNTATNMLIARLGGI -DALNQRFQSWGLTTTAIRNILPDLGGT------NTTSPKELSTLMAMVGKGNLVSMRSRD -RILDIMRRTVR-NHLLPAGLGPGATIAHKTGNIGT-ILGDAGLVDVPTGKRYVVSVMVQR -PRND-PGAEKLITSISRVAYEQ- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis novacekii Mn_MB_F_20050700_S1D TaxID=2486266 RepID=A0A552IF07_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=E4PYM7_STAAU ------------------------------------------------------------- ----NKLNKKIHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Chroococcales cyanobacterium metabat2.561 TaxID=2485785 RepID=A0A3N5IDN2_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter citreus TaxID=225971 RepID=UPI0012EED6EA ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRAGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] class A beta-lactamase n=1 Tax=Rhizobiales bacterium TaxID=1909294 RepID=UPI000DD521F1 ---ALQQRLEKLATGKDARIGICALD-QAGTSV-CVRGDERFSLQSVVKLIAGAATLDAAD -HGAVNIEDPIIIRSENLSLKQPLAKIVERNGTNAGDLVRRAIIDSDSAAVDILINRLGGT -GKINSFLAGKAISGIRIDRDERHLQTAYQKDPRDTATPRAMTEFLAALMSGKLISTSSTD -RLLAIMNETSTFPDRLRAGVGNDWSVAHKTGTSPNVATNDVGILTAPDGGKVAISVFVAD -SRETPTRRATIIASAAQAVTEAy ->[subseq from] class A beta-lactamase n=1 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=UPI000DEF41E2 ----LQQRIATLAEEAKGIVSVSCSLPRTNLNC-DLNAHGHQPMQSAFKLPLGLAVLHAVE -QGQLSLDQQVRFLPSDIYKFSPLQDMYPNANVPLRQLLELSVGRSDNTATDILLRLMGGT -GPVQSYLDTLGLQGIQIRDSERSLHDDERRQYRNFAEPAAFVKLLRLLADTSPLNAEHAQ -YLLAIMTASPSGPKRLKGLLPAGTIVAHKTGTSGYEATNDVGLITLPDGRRLALAVLVTD -AHADEAAVEHTIASIAHACYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Pelosinus fermentans JBW45 TaxID=1192197 RepID=I8TYI8_9FIRM --kELQKKIEATLAAYRGRGGMVILNHSSGQHF-ALNPDMVFPAASMIKIPIMYEVMRQAA -AGRIDLEQLLIVKDELRVDGAGILKERPGISMTIRELVTLMIILSDNTATNMLIDLL-GM -SPVNQTMERLGLKSTVLRRQMMDFAAA-AAGQENETSPADIIRLLTTIYDHTDLPADYGK -LMIEILSRQQV-RDKLPFFLPEEIVIAHKTGTLP-GVEHDGGILFLPGG-PYIICIMTAD -LAAN-VEGLQLVATLGKVIYEHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 37zxx TaxID=1550073 RepID=UPI0009DF97FC ------TAIDTMVENFGGKVGVAVKSIDDDWMI-SKNGDVPMPQQSVSKLWVAMTALDLVD -QGKLRLDEQLTITRADLTLHQPIAGLLKNGSATAGELMRRAMTMSDNTANDRLLRRVGGP -DAVNAFIKRKSLGAIKFGPGERLLQSNYVADPIDGAAAAAIANALARLKQGDLFSRASTA -HLVTLMESSRTGAARLRAKVPPGWRLGHKTGTGQTAGFNDVGFLTAPNGRSYTIAILIGD -TSRPVPERQQLMQKVVESVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter mirabilis TaxID=69666 RepID=A0A2D2B0H3_9CAUL --eRLDARLERMGRAFGGRIGIAVYNVDEGWAA-DFNGDALLPQQSVSKLWVSVATLDRVD -RGELSLDDRVLIRKEDLSLHQPIRAQVGEHGTTVRDLMRRAITQSDNAANDALIRRIGGP -WAVQVTVVAKNLGEIRFGPGEREMQTAYVENPPDGASALDIAETLGRLKGGGLLSPGSTA -FLLGLMAETSTGSSRLRASLAPGWTLQHKTGTGQATGYNDVGLLTAPDGTAYAVAVLIGA -SRRPFKDRSSLIAEVGRAVIA-- ->[subseq from] class A beta-lactamase n=1 Tax=Burkholderia sp. E7m48 TaxID=1561197 RepID=UPI0006D3F342 ---DLARQLARIEAQAGGRLGVAILDTASSKPQ-GWRMHERFPMCSTFKFLLASAVLVCKD -QGKEQLGRKIVYAKEVVVANSPVSGPRAGGDMTVGELCEAAITRSDNTAANLLLDSIGGP -AALTAFARSIGDRVTRLDRNEPSLNEATQGDPRDTTTPAAMLADLRALL----------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. SLTY TaxID=2683262 RepID=UPI001412D3AD --eQLQGRLDALARSFPGDVGVAVTRVDEGWTV-SVNGDRPLPQQSVSKLWVSMAILAAAD -RGELSLDERVTIRKEDLSLHQPIRKFVGEAGASLRSLMDGALQSSDNAANDALVRRLGGP -FAVQVAIVGKNLDGIQFGPGERAMQTAYLADPPDGATALGVVEALSRLYRGDLLSPDSTA -LLLERMGGSHTGASRLRAGLPPGWKLAHKTGTGQATGFNDVGLLIAPDGRVYAVAVLIGA -TRQPIEARQAFIASVASAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D8FIQ5_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTXERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9G5I2_9BACT --qKLEAAIQDIDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ -QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM -ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMLLLLEDLYRGKILNKQMTD -DFFELLSIHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNR-PFVISVMTTY -LHRE-KDGGEAIIRIATAAYQMf ->[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA9273 TaxID=2055791 RepID=A0A352ABC2_9CYAN ----LKTQIQTLASQNNLQPGVFMVDLDTGAYL-DSDSQSIFPAASTIKVPILVAFFQDVD -AGKIRLDEPLTLEPEAIATGSGDLQKQPGSQYVALEVATKMIAISDNTATNMIIKKLGGA -AALNQRFQSWGLTATVIKNPLPDLEGT------NTSSPRDLANLMFMVNQGELVSLRSRD -RLLDIMQRTVN-NSLIPKGLGAGAIIAHKTGDIGS-LIADVGLVDMPTGKRYIIVAMVKR -PHND-GSGAELIRQISRAAYNYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15A TaxID=2714942 RepID=UPI00140A2B11 ------------------------------------------------------------- ---------------------------------SARSLMEAMMIHSNNQATDLLLGNLGGP -DKLQQWLQERNVKGIRVDRNIADLLAAKRWDVRDSATPRAMVELLRRIDKGELLRPSSRA -YLLNLMARCQTGKNRMRALLPASAQVQHKTGTLNN-YTSDVGYFTLPDGRRLAVAFFARG -GS----NRPQTIAMAARTIYDGf ->[subseq from] class A beta-lactamase n=1 Tax=Undibacterium sp. YM2 TaxID=2058625 RepID=UPI001331EDAB -----QNVIESIAMDSGGRLGASLLVLETGQSL-WILPDTAAPMQGVSKLPIVMAALAAVD -KNKLKLDQKVTINKEDLIPPSALRDEHPEGNITAKELMHHAIVDNDGTASDALLRLLGGP -PAVMQYLAQLDIKDIKVLDTEKDLAKSWNMQYRNTATPKAMIKLLQTVQEGKALSPKSRE -LLLKWMTDTEVNAARIKALLPAGTAVVHKAGSSPTAAHNDVGIVTLPNGLHMAVAVFLTD -SKAPHASRDLTIAKITRVGWDAw ->[subseq from] Beta-lactamase class A n=2 Tax=Brevibacillus TaxID=55080 RepID=J2HUE3_9BACL ----WQKALEKALADAPGVFGVAAEHLETGESA-GQLDDQLFQLASAFKIPIMVTLMREVE -AGRVRLDQRVVTQKDTRVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLIIELVGGI -DKVEAHMHELGLKQIHLRHTCWQLLNSLPTLDNNVATPRDLNRLLMLIARKEILTQASCE -LMLDILRRQQF-NSRLPYLLPEGTKVAHKTGTVN-AVVNDAGLIYLPDGGTIAITVLSRG -VT-DKQAAELAIARAARAIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter citreus LAMA 915 TaxID=1306953 RepID=A0A0L1KBD5_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRAGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V584_9BACT -------------------------------------------------VMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLKNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPTSWVV---------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W5AYQ9_9SPHN ---NLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQAAAAAVAKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Xenococcus sp. PCC 7305 TaxID=102125 RepID=L8M4S0_9CYAN ---KLKDKLSSLTANYQLEAGVYIVDLDNKNYV-NFNGSQAYSAASTIKIPVLVAFFEDVD -AGKIRLDEKLVVTKEVIGGGSGYMQKEIGTKYSALHTATDMIRVSDNTATNMLIQRLGGM -EVLNQRFAEWGLNNTAIRNPLPDLTGT------NTTSPVDLGNLLIKINRGDLISLRSRD -RLLAIMRTTKT-RTLLPQGIEKDAVIAHKTGDIRS-SLGDAGIVDMPNGKRYIVSVLVKR -PAN-DPQAKILIQKISQTTYQH- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_QC_Ch_20071001_S25D TaxID=2486250 RepID=A0A552FYD6_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETFVATKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNRRFQAWGLTSTVINNALPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Phormidium sp. OSCR TaxID=1666905 RepID=A0A0P8C7J8_9CYAN ---ELDDQLQELLGAYELTPGVMVLDVATGDYV-QLGEDAPFAAASTIKIPILVAFFQAVD -GGQVRLDEPLQLQESHIQGGAGSLQDEAPGLLSALEVATLMIVESDNTATNLLIDRLGGM -EALNDRFRQWGMTETVLQDWLPDLQGT------NTTTPRELAGLLAQIERGELLSMASRD -RLLRIMMLTEN-DTLLPQGLGSGAVIAHKTGNLR-GVLGDAGLVDVVNGRRYVVVALVER -PEYD-EEAVTLIRELSARVYGYf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E8D3G6_9PLAN --eELAGRLRPLIANHEGDVAVAIRHLETGEAF-QHDGGKVMPTASLIKFPVMVEAYRQST -TGEADLDSMIELRDEDRVPGSGILTNHFSSGLSLRDAIRLMIVYSDNTATNLVLDRI-GL -KSTADTMQTLGFLDTKIHAKVFRRDTRSSKYGLGSTTAIEAVRLYELLHKRRLITAEASD -AMLDHLLHCDD-RRKLAAMLPTGTEIAHKGGAVSR-VRCDAGIIYSPSG-PIAICVLTAN -NQGKDNAAEQLCARIAKTAYDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A538RXA1_9BACT -------RITAIDRRLDGVLGVAILDLTSGQKF-LLHGDEIFPQASSIKIPVLAELYRQEQ -AGKARLTDPYTVREADLVPDSDILLGLTPGVLTNRDLATMMVAVSDNSATNILIDRL-GM -ENVNALLDSLGLAHTRLRRKMMDLKAA-QEGRENVSTPRDMMTLLEALHQGKVLNKALTA -DFFKVLATHKD--SALLRGLPDGVRAATKPGALE-GVRNDSGIVFAKNR-PFVLCIMTTY -LR-NEKQGEQAISDIAAAAYQHf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-2519 TaxID=2303981 RepID=A0A5A5RAQ0_MICAE ---SLNQKLQALVVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Microcystis TaxID=2643300 RepID=A0A2P1UFC7_9CHRO ---SLNQKLQALVVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLGDAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Microcystis aeruginosa NIES-2521 TaxID=2303983 RepID=A0A5A5S073_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2E9CHH1_9SPHN ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD -AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP -TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ -DHKGHATRDRIMAEAARASYDYf ->[subseq from] class A beta-lactamase n=1 Tax=Aphanizomenon flos-aquae TaxID=1176 RepID=UPI000489F8E5 ----LKNSLQTLSANADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD -AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVGMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WNC4_9BACT --rELTEQLRSLCDAVAGDIGVAVVHVESGKTV-AVAGDKKLPLYSVYKLPLAMTVLRDVE -AGKLRLDQKVKVTPADVAGTLFNTDLRSAQEKTVRELIEYAIVRSDNTSADKLLGLIGGP -PIVTQEMRTIGLANIDVVVSSREFTAH--RDKPNTGTTTDLAQLLARLQKGELLQPANFS -LLRDYMERAKTGERRLRANLPAGTQVADKTGTGDV-ATNDVGLITLPNKGHLAIAVLISG -SKLPVDKQEKTIADIAR------ ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3A0DMA7_9BACT --qSLAERIEPLIKGHKGTVAVAIKHLSKDAAF-AYRGDEPMPTASLIKLAVMVETYRQAE -EKKVDLAKSITLAENDKVPGSGILTPHFSAGLSLRDAVRLMMVYSDNTATNLVLDQI-GL -KSTADSMEKLGFPNTKIHAKVFRRETRSKKFGLGSTTSNEMVGLLAKIHGKQVVSAAACE -AMLDHLRACDD-RTMLPALLPDGVKVAHKTGAVS-AIRTDAGVIESRAG-PIAICVLTAE -NSTDDNAAKVLGAKIARAAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Gloeothece TaxID=28070 RepID=E0UHR7_GLOV7 ------KKLMDLVPKYKLEARAFFVDMDNGNYV-DINAQAPIPAASTIKIFVLVALLEQID -AGKVRLDEQLTMTKDIVTSGSGDMQYPVGKKFTVLETATKMIIISDNTATDMLVKRLGGK -QVLNQRFREWGLTNTIINNILPDLEGT------NTTSPRDLAYILMRVNQGELLSLKSRD -RMLNIMQQTKT-RTLLPQGLDSDAIIAHKTGDIGT-VLGDAGIIDMPNGKRYIGAVMVKR -PYND-TAGRMMIQEISRTVYQH- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2E7M559_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRSGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Uncharacterized protein n=2 Tax=Parabacteroides sp. An277 TaxID=1965619 RepID=A0A1Y4DGR5_9BACT ---DLGTQLRKAIEGKAATVGVAVIF-NGSELV-TVNDMYRYPMMSTFKFHQALSVVDYIN -RKEKTLATEILVKQSDLKTYSPMRDANRKGNITIGDLLKYSLIDSDNYACDILFEHIGGP -KTTDKYVRGLGIEDFSITQTEREMHESTDNVWLNWTKPSAAVLLLETFLQNPMFDKSQKL -FLERAMADANTGKDKLKAGLPNDVLLGHKTGSSDRNADNDMGFVVLPNGQYYTIAVFVMN -SQESDKTNARLIANISKIVYNYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteriales bacterium 13_2_20CM_55_8 TaxID=1803470 RepID=A0A1Q6XCW1_9BACT --qKLESAINDVDHSLDGVLGVTILDLTSGQKF-LLHADEVFPQASSIKIAVLAELYHQTQ -SGKLKLNDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -ENVNGLMSSLGLTHTRLRRKMMDLKAA-SEGRENISTPGEMMVLLENLYRGKILNKEMTE -DFFKVLSTHKS--SFIPLDLPEGLKIANKPGELE-GVRNDSGVVFVEKR-PYVICVMTTY -LQR-ERDGEEAISRISLAAYRMf ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9W972_9BACT ------SGLEKAAANWRGNVGIYIGDLHTGRNW-DYNADRLFPSASLIKVPIMAAVFDRIK -SGAITLGTQIRLTRADRVGGSGSLRWVRDGTLSVMEIIYKMITESDNTATKMLIDYV-GM -PYLKTAFKQLGLVHTNITQEGMSLSSG-RIARENYTTAREMAGLMERIYAGELVDREASE -FMLDVLKHTKS-RSRLRKGLPLGWEIGHKTGLLRK-SCHDAGIVFSPRGD-YVIVVLTSE -VP-DYASAKKFISRVASLTYTYy ->[subseq from] HGF-1 beta-lactamase n=1 Tax=Bacteroides sp. CAG:20 TaxID=1262738 RepID=R5ES05_9BACE ---TVGQKIRQAIQGKNATVGVAFSI--DGQLF-TFNDEHRYPLMSIFKLHVAIAALQKME -NECIALDSLRFIESSQIHKYSPLRELYPERNLSYADLMRYAVSQSDNNACDILIDYLGGI -DIVKDRIDKLGITNYNLTETEETMHSRISNCYNNWSTPSSTLQLLEKLYNEPILNETHTE -FLKNILIETSTGKDKIKAGLPDNIVLGHKTGSSDKIGDNDTGVIYLPNGKLCFLTIFIKD -SRESDQTNTQIIADIARIIYN-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium xenophagum TaxID=121428 RepID=UPI00039C29CF ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD -AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP -TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVTAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ -DHKGHETRDRIMAEAARASYDYf ->[subseq from] Penicillin-binding protein n=1 Tax=Anabaena sp. WA102 TaxID=1647413 RepID=A0A0K2LYD9_9NOST ----LKNSLQTLTTNADLMPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD -AGKIRLDEILTLQKEMIVGGSGNMQYTPDSKYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNVVGMRSRD -LMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYEHf ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001448637C ----LKNSLQTLTTNSDLISGVFLLDLDSGGYI-DINSNASFAAASTIKIPILIAFFQDVD -AGKIRLDEMLTMQKEMIAGGSGNMQYTPGSKYTALDVATKMITISDNTATNMLVAKLGGQ -EELNGRFRSWGLTTTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNIVSMRSRD -LMLNIMNRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A353CT26_9BACT ------SALSKASIAYPGRVGVYLKDLRTGRTW-AYQPDCLFPAASLIKVPIMAAVFDKIA -RGELSLETRIRLTGKDRRGGSGSLKWAREGTLSVMELLYKMITESDNTAAQMIIDHA-GY -SYLEHAFRKIGLVYTNIAPEGMSLTSG-RVARENYTTPREMALLVDRIYAGAMINRESSQ -LMLDLMKHNK-GRTRLRKGLPMGWEIGHKTGLLRR-SCHDVGVVFSPRGD-YIIAVLTGE -VP-SYSSAKRFIAGMAKLTYGYy ->[subseq from] Beta-lactamase class A n=1 Tax=Rivularia sp. PCC 7116 TaxID=373994 RepID=K9RHF0_9CYAN -----KSSIQSLVAATNLTPGIFVANLDSGNYV-DINASTSFSAASTIKIPILVAFFQDVE -AGKIKLNEPLTMTKDMIAGGSGMRSKPVGSQFTALEVADKMMVISDNTATNMLIARMGGI -DALNQRFRSWGLIATSLQNPLPDIQGT------NTTSPKELAQVIAMVSKGQLVSRQGSQ -QILEIMRRNQR-RHLLPKGLGAGARIANKTGYIG-AMLGDVGLIELPSGKRYIAAVMVKR -PRND-SRAETLITSVSRSAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Barnesiella viscericola DSM 18177 TaxID=880074 RepID=W0ES43_9BACT ---KIDSEIRIISQRHDATIGVAFS-LDNRLYI--YNDSIRYPLMSVFKLHVAVAALQRME -AKGTQLDEILQIDSSQMQRYSPLLDRYPSGSISYADLLHYALALSDNNACDILIDYAGGI -EAVKACTDGASLTGYDLTETEASMHEHIPACYHNWAHPSSVVQLLQKIHDGALLNEEHTR -FMINTLIETSTGNNKIRAGLPAGITMGHKTGSSGTIADNDAAFIYLPDGRLCYLVIFVKD -SHETDSQNADLIARITRIIYN-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. PAMC 26605 TaxID=1112214 RepID=UPI00026CD65C ---ALATSVAILARQFDGRVGIAVRSIDRGWSV-DAGGEQRLPQQSVSKLWVAMTVLDYRD -RGRLRLTDPVTLYRDDITLHQPIAGLIKGDQTTVGELLQRALTMSDNTANDRLLRYVGGP -NSVRDFMQRKGLGDIRFGPGERLLQSRYVADPPDGAAPVAIAGALARLKRGDLLSPESTT -YLISTMESSHTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLTAPDGSSYAIAIMIGD -TPRPIPARQALMQAVVASVVA-- ->[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI00130B3348 ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=2 Tax=Microcystis TaxID=1125 RepID=A0A552LN84_9CHRO ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKAADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. B2966 TaxID=2656761 RepID=UPI00140BEB5B --qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -KNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT -KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD -FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARMIADISQVVYNFy ->[subseq from] Beta-lactamase SHV-1 n=1 Tax=Raoultella planticola TaxID=575 RepID=A0A485A5N2_RAOPL ------------------------------------------------------------- -----------------------------------GELCAAAITLSDNTAANLLLTTLGGP -QGLTSFLRHSGDQTSRLDRWETELNEARPGDVRDTTTPQAMARTLRNLLTGRVLSSASQQ -QLQRWMVEDKVAGPLLRSVLPAGWFIADKTGAGNRGSRGIIAALGPDGKAARIVVIYLTG -TPATMDERNKQIAAIGATLIRHw ->[subseq from] Serine hydrolase n=1 Tax=Sphingosinicella ginsenosidimutans TaxID=1176539 RepID=A0A5C6TWS2_9SPHN --sALEQRITELGRGFNGIVGIAVRDVESGWTT-SWNGRRYFPQQSVSKFWVAITALQAAD -QGRLDLSQNATLTRADLTLHQPVAADIGPNGTSLDNFMFRALTTSDNTCNDMVLRHAGGP -AAVRAMLERNHIEGIRFGPGERIMQSHYVEDPVDGAMPEGIVDGLARLQRGELLSQRSTA -RLLSILAAVRTGPQRLRGGLAPGWQIAHKTGTGQQAGYNDIGILTAPDGHHYAVAVMIGR -TATPLPTRMALMQNVTRAVIAY- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG08_land_8_20_14_0_20_51_18 TaxID=2014309 RepID=A0A2H0ZBF6_9BACT --nDLTSQLEEAARKYPGRVGIYLKDLSQNHEW-TYRPDRIFPSASLIKVPIMASVMRKVE -KDAINMDTELRLTHKDRRSGSGSLKWAREGTLSLLEIIYRMITESDNTATQMLLDYF-GM -NYFEEEFRNLGLAYTNITQDGMSLTSG-RVAKENYTTAREMGYLLEKIYAGELISRKASE -TMLDILKRNKS-RGRLRKGLPLGWEMGHKTGLLRT-ACHDAGIVFSPRGD-YLIVVLTSK -GP-DYRSAKNFISKIAKITAAYy ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=UPI001431B6A4 --kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA -TKLNQRFHNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVSMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Cloacibacterium normanense TaxID=237258 RepID=A0A1E5UFT6_9FLAO --nELKNKIEKIISTENGDFGVSIID-ENNNIV-EINGKKHYPLLSTFKFPIALTILHKVE -KRELSMQQQIFIKKEDLLEWSPFKEKHPDGNISLEEAINWMIVYSDNNLTDILLRLLGGT -ETVQKFI---DDENFVIKNNEDEMHRDWNSQFINKSTPNSFAQLLKKFSEGKILNSENTK -WLYQSMVKSETGVKRLKGKLP-NVKIAQRAGTSFTGAINNVGIMELPNNQKIYIAVFVHN -TSEEFSKGEEIIADIAKTTYEFy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas soli TaxID=266127 RepID=UPI00083691CF --qELVSSLDALTRNFGGIAGVSVASVDQGWLI-SSNGERKLPQQSVSKLWVTMTVLDQID -QGKLSLDTPVSISREDFTVHQPVAALVKDGQTTVAELIRRAMQMSDNTCNDKLLRLVGGP -DAVREFIARRSLGPIRFGPGERLLQAAYVADPPDGAAPLAIAGALARLKRGELLSPTSTD -WLIKTMEAARTGKARVRAAVPPGWTYAHKTGTGQTAGFNDVGILTAPDGRGYALAVMVGD -TNRPVRERQLLMQQVASAIVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Butyricimonas sp. An62 TaxID=1965649 RepID=A0A1Y3W3I4_9BACT --kELEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVANYYE -KKGLSFDTPIYIRKTDLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFQQTGGT -EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG -FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD -SEESEAATARIIADISKTVYRH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A0G3VS34_ECOLX ----------------------------------------------------CGAVLSRVD -AGQEQLGRRIHYSQNDLFEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLR------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A380FJG6_STAGA ----------------------------------------------------------QVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. D43FB TaxID=2017595 RepID=A0A2A3MZU7_9SPHN ---TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD -RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR -LLLTVMAEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] Serine hydrolase n=2 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=A0A367PY31_9NOSO --kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA -TKLNQRFHNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVSMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYDY- ->[subseq from] Beta-lactamase n=2 Tax=Nostoc punctiforme TaxID=272131 RepID=B2IVV4_NOSP7 --kALEPQIKALMNRYSLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLIMRRDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGV -TKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYDY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. B2 TaxID=2583228 RepID=UPI0011A6ED31 ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID -AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP -TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGIISLPDGRLFAITVFVMQ -DHKGHETRDRIMAEAARASYDYf ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A520VJE3_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPDDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LVLGTLARTHSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] class A beta-lactamase n=1 Tax=Luteibacter sp. 9133 TaxID=1500891 RepID=UPI000689CEE4 ---TLQASLQKLADQAPAKFGIIVVDLDGSASA-KVNDDRAYMLMSTFKAPVSAAVLHQVD -AGKLRLDQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAVTQSDNTAVDALLKLVGGG -EVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK -RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGNRAVVGAFLRD -TTSTDEQRAAWFKELGTVVSK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 32-62-10 TaxID=1970436 RepID=A0A258G0R8_9SPHN ------STIQTLRAQFAGNVGIAVRNIDKGWAV-TANGSTKLPQQSVSKLWVAMAVLDYRD -SGQLTLDDTVTVTREDLTLHQPIAAMVKGDGATVGELLQRALTTSDNTANDRLLRFIGGP -ETVRGFIRRKGLGSISFGPGERLLQSSYVTNPPDGAAPEAIAGALAMLKKGELLSANSTN -YLIATMESARTGKQRLSGAVPAGWRFGHKTGTGQTAGYNDVGILTAPDGQSYALAVMIGD -TPRPVAERQALMQSVVASVVAY- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. MI1205 TaxID=407020 RepID=A0A126RAN6_9SPHN -------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMAVLDAVD -RGKLRLSDTTTITRKDLTLHQPSAGLVGSTGTSYSDLMRRAMMNSDNTANDTLLRSVGGP -EAVRSYLARRFIKDVRFGPGERLLQANYLASPPDGAAPSAIVHALAKLKEGDMLSPASSR -LLMSIMSEAKTGPQRIKGGVPAGWRYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTEPIPARWELMQAVARAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium tetanomorphum DSM 665 TaxID=1230342 RepID=A0A037Z4T8_CLOTT ---ELENLIEDIINNSKGDIAVAIKNLESNSTI-MINEKEVFPSASTIKLLIMVTAMQEVK -EGKRNLKDKIIISTEEKCGGDGILKELNKDHFTLIEIITLMIIISDNTATNILIDML-GM -DNINKIANELKLNNTRLQRKMMDSE-AVKMGKENLTTALDMCTILEMLYKGEIVDKEYSN -IMIEILKKQQV-NGRLTLYLPDDLVVAHKTGDLDK-LEHDVGIVYYPYCN-YIICVLTKN -LY-TNKEGREIIGKISYEVYKSf ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingobium TaxID=165695 RepID=A0A560WSK9_9SPHN ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMVD -AGALTLEDQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP -TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKVLSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLIAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ -DHKGHETRDRIMAEAARASYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V579_9BACT -------------------------------------------------VMAAAAVLKKSE -SGPSLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVAAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVV---------------------------------- ------------------------ ->[subseq from] CTX-M family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6D1LVG4_ECOLX -----------------------------------YRADESFAMCRTSKVMAAADVLKQSE -TQKKVLSQKVEIKSSDLINYNPITEKDVNGTMTLAELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFDRAIGDNTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGSALGETQRA -QLVTWLKGNTTGAASIQAGL---------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingorhabdus sp. IMCC26285 TaxID=2509718 RepID=UPI001366125C ----LENLIQEQWKQFPGKTGVAILRIDGGEWViGRRLDELFPQQSVSKTWVALTILDLVD -QGKLRLDQKVRITADDIAVHQPIRERVLAKGESVQSLLEQSITASDNTANDSLLRTAGGP -QVVRSFIARKKLGAIRFGPGERVMQSRYLADPVDGASPVAIVRALGKLARGELLSPTSTR -LLLDIMSRTSSGPNRLKAGVPVGWKFVHKTGTGQSTGYNDIGIMTAPDGTRYAMAVMIGS -TTASIPERMAFMQFVSRTVATY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus soli TaxID=2601267 RepID=A0A5C6ULE0_9SPHN ---ALTERIDQLWASFPGKTGIAVRRIDGDWSY-AKRGDEYFPQQSVSKLWVTMTVLDAID -NGRLSLSTPVDIGPENLTVHQPIAARVAREGETVGSLIEQAITHSDNTANDSLLRTAGGP -DVVRGFIAKNGLGPIRFGPGERLLQASYVADPVDGAQPSAVVAALAKLARGELLSAQSTK -LLTETLSRTHSGPQRLKGGVPAGWQIGHKTGTGQSTGYNDIGILTAPDGTRYAIAVMLAE -TTASIPERMRLMQNVVRAVVDT- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aquaemixtae TaxID=1958940 RepID=UPI00135F4723 -----ERRIAMAADGDMGRIGVAAIDLSTGDRI-SVLGDQRFPMASTSKVAIAATFLAGVD -QGRWSLTSEYPLLIPVRSAYSTRVAPVRHGNITAQNHLELMISKSCNACTDALLKVVGGP -SAVNAFMRNAGIHDFQLTRDIATLVRVVTIDTRDSASPNAMVKLLADIYQGRLLSPQSRA -ILMDAMRGTTTGKYRMRSSLPSSANLAHKTGTLTR-TASDIGIFHTPDGRAIAIAIYVTG -QSQSRRLRDDRISTIAREVYNAf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas prati TaxID=1843237 RepID=UPI0012F6E25D ---ALAATIKRLGRGFDGIVGIAVRDVQAGWFI-SFNGSGYFPQQSVSKLWVALTVFDAID -RGRMSLSDTVRIERKDLVVHQPMRGKVGAAGASVSELLLAAMTTSDNLANDSLLRTVGGP -GAVRAFLARSQLTGIRFGPGERLLQAKYLADPIDGAQPEQVALALARLRKGDLLSPVSTQ -RLLTLMASSKTGPQRMRAGSGPGWAFAHKTGTGQATGYNDIGLMTSPDGRTYALAVMIKT -TRQPIPVRQRLMSDVARAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11370 TaxID=2055769 RepID=A0A350Y9A1_9CYAN ----LKSQIQALAAQNKLQPGIFLVDLDTGTYV-DWQGQSILPAASTIKVPILVAFFQDVD -AGKIRLDEPLTLEPDVIGTGSGELQQKLGHQYTALEVVTKMSAISDNTATNMIIKRLGGA -AVLNQRFQSWGLTATVINNPLPDLEGT------NTTTARDLGNLMGMLNQGQLLTLRSRD -RLLNIMQQTVN-NSLLPKGLGSGATIAHKTGDIGS-LVGDVGLVDMPNGKRYIIVTMVKR -PHND-GSASELIRNISRTVYNYf ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YKH8_9BACL ---SLQQKLEDLLRETRGTFGIAVKNLQTGEEA-SINADRLFQLASVFKIPILATLYRDVE -AGKQTLEQRITITETDNVPGSTILASLDWGVLTMKDLAMLMIIVSDNVATDVLLKMI-GV -QNVDSYMKQLGLENTFINHSCWELLSFKADKRGNVSTATEMSRLVEMIANEQLLTKTSTD -GMMDILGRQQF-KNRLPQLLPSQAKVAHKTGTLPPGIVNDVGIVYMPDKGAFTIAVLSQG -NP-SVADGERMIARIARTAYDHf ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3D2LCS1_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRSGDLTVHQPIRDIVRRDGADYSELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LLLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomyces sp. SH-PL14 TaxID=1632864 RepID=A0A142WZA5_9PLAN -----AGVLTPLISAHEGEVAVAVKHLAKGDEF-THRPTETMPTASLIKLAILVEAYRQSE -AKTLDLAKLLDLRKEDMVPGSGILTDHFPVGLSVEGAAHLMIAFSDNTATNLVLDQF-GM -KAVNETMAGLGLPETRVHSKVFRRDTSIDPDRSGSTTARDMLTLLEKLHGGTLVSGPASE -AMRKHLAACDD-KLKFPRLLPKDVKVLHKTGSVAN-VRTDAGWIETPAG-PIALVVLTAN -NKGDTNAGDLLCAKVARAAYDHf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X844_9BACT --hELEQRLKTISDGSQGTVGLSVVHIESGKTV-SINGSSQLPLYSVYKLPLAVTVLKDVE -EKRLRLDQKIHITPQNVVQGTTANSALWQKPYTVEQLLEFSISRSDNTSSDKLVELVGGP -LQVTERMRSLGFQNLDIHISSGEFVKT--RQNPNTGSSDDLVQLLVQLHRGKILQPAQVN -LLRGFMQRATTGLHRLRGDLPRGTVVADKTGSGEAKVTNDVGIITLPRGGHLAMAVLVNG -SKLPDAAQEKLIADLARAAYDAy ->[subseq from] Beta-lactamase n=2 Tax=unclassified Nostoc TaxID=2593658 RepID=A0A2L2NGT9_9NOSO ----LEPQIKALMNRYNLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRGDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGV -AKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSPQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYNY- ->[subseq from] Beta-lactamase n=2 Tax=Pedobacter westerhofensis TaxID=425512 RepID=A0A521FJT7_9SPHI -heGLRNKIRAYASNGKCKVGVAIRLLETGDTL-SHGDAVLYPMQSVFKFPIAMSLLIAAD -KGEIDLNQRVHIKKEELKKVSALYDKYPDGNVPLLEVLSDMVTKSDNNACDIIMKILGGG -DRITRDIHRLGVPAFTVKVNEAQMSSEWPLQYLNVCRPSAQIQLLDILLNKPVLSNKNRD -LLLEMMHHTFVTPNRIRRFLPAGTPLAHRSGTSSTKATNDVGLITLPNGNHLAIAVFVAE -SYEEMDARELIIANIAKAAYEEf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Sphingobacterium kitahiroshimense TaxID=470446 RepID=UPI00143C5528 --qQLQERIKHIIDTTGGNIGVGVQGMDFKSGF-IINGNHEYPMMSVFKFPLAFAILDKVD -KGELKLSDKFHMPKASLDTWSPMVKDFPNQDVTLADLLTYAVSKSDNNACDFLYTKVGGP -VAVNQYLHHAGVKDISIVYTEGEMEKDWALQYKNWCKPAGAIKLLQLLYNQQLLSKTSND -FLIQIMRELPDWGKRITVLLPPTAELIHKTGASGMAAFNDIGIITLPNGQHLAIAVFVSD -FKAPQQRGINVIAAISKEIWDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-F2F-G114-C0414 TaxID=2135662 RepID=A0A3M0EQR3_9SPHN ----LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLTKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQQAAAAVAH-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000DBE3660 ------------------------------------------------------------- ------QNQKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6MBZ5_9BACL ---NLQQKLESVLSESSGTFGVAVKHMGTGEEA-QIRAEQYFQMASTFKVPILAALFRDAD -AGLVSLEQRYRLSEADLVPGSGVLKEFLPGAVALKDLATLMIIVSDNLATDKVLEII-GK -ERVEAYMRELGLTQISIKHDCWELLSFQASPENNVATPADMGRLLELIGTGKLASEQASD -GVLDIMKRQQL-RNRIPYLLPDETIIACKSGTVGH-VVNDVGIVYLSDDGAFAIAALSSG -NP-SVKEGERVIARLAQTAYEHf ->[subseq from] Class A beta-lactamase n=1 Tax=Erythrobacter sp. KY5 TaxID=2011159 RepID=A0A2Z4K3Z5_9SPHN ---RFEAMLRQIEGEADGTLGVELFDVSTGHSV-GINRDRKFGHCSSFKLSLAAMVLASDS -LGIVDAARRVMWSEDDLMFVSPFTTQRLTQGATLHELAEATQKYSDNTAANILLREYGGP -QALTAFWSGIGDNVSRLDRYEPRVNYVPVTEYRDTTTPAAMARTVAALAFGGVLPDAERA -LLRQWMIDTETGARRVRAGLHEELVGGDKTGTSIGSLYVDIGFVQPPKSGPFTFATYFRT -RTATDPSAEAALARVG------- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9GUN5_9BACT --qKLEATIQDVDRNLDGVLAVAILDLTTGQNY-LFHADEVLPTASSIKIAVLAELYHQAQ -QGKLKLGDLYTLESSDLVGGSGVAGALTAGVLTLRDVAALMISVSDNSATNIIIDRI-GM -ENVNALLNSLGLTHTRLRRKMMDLKAATEG-RENIATPREMMLLLEELYRGKVLNKQFTE -DYFNLLSIHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFLGKR-PYVISVMTTY -LRRE-HDGGKAIIRISNAAYQMf ->[subseq from] Uncharacterized protein n=2 Tax=Bacteroides TaxID=816 RepID=R6CIK0_9BACE ----LESKIKKSIENVPAQVGVAII-INGKDTI-TVNNECHYPLMSVMKYPQALAVLHYLH -QHNQPLSTKIFIPKEALLDYSPLRDKYPEGNMPIAQLLDYTIQKSDNNACDILFNYTGGV -SYTDSYIRSLGINNFSISKTEDDMHEDLAACYENWSTPLEIASLTDMLFSKELFPTEYQN -FLKETMLNCQTGTNRLPAPLDTTARIGHKTGTSDRNGINDVGFILLPDGKRYTIAVLVKD -STESMADTEKIIANISGIVYHH- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Leaf357 TaxID=1736350 RepID=A0A0Q5R9M3_9SPHN ------------------------------------------------------------- ----------------------------------AAKVLELMIVRSDNRAADQVLDSVGGP -AALQQWLSTQKITGIRADRTIAQLLRGHLADSKDVATPVAMVTLLQKLDSGTVLTAQSRT -FLFGLMSRCATGTRRIRALLPAGTPVEDKTGTLD-GVTNDVGFITMPDGRRVAVAVFARG -GR----DHQPVIAQVSRAIYDRf ->[subseq from] Beta-lactamase n=1 Tax=Calothrix parasitica NIES-267 TaxID=1973488 RepID=A0A1Z4LLD8_9CYAN ---------QSLVAASNLTPGIFIADLDTGNYV-DINGNNSIASASTIKLPILVAFFQDLE -AGRIELNEPLKMTKEMIAGGSGNMRKPVGSEFTALEVADKMMVISDNTATNMLIARLGGM -EALNQRFRSWGLTATTLNNKLPDIQGT------NTTSPKELAQVMGMVTKGQLVSSTMSQ -RIIEIMARNQR-RHLLPKGLGAGARIANKTGFIG-AMLGDVGLIELPTGKRYVVAVMVKR -PRND-PRAETLIPSISRSAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=A0A2W5B057_9SPHN ---ALVAAINALGGGFQGKVSIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTVMNAID -EGKLALTTPVTITRGDLTLHQPIAYLMKNGATTVGDLLRRALMMSDNTANDKLLNLAGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLTPQSTN -WLLDTMSHTRTGRARIRAALPTGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVMIGD -TARPVPERQQLIQTVVSSIV--- ->[subseq from] Putative beta-lactamase protein n=1 Tax=Microcystis viridis NIES-102 TaxID=213615 RepID=A0A3G9JQ63_MICVR ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDEPLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NSTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSANIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium RIFCSPLOWO2_12_FULL_63_15 TaxID=1802170 RepID=A0A1G3K1E9_9SPHN ---TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD -RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR -LLLTVMAEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GNJ1_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGALLTRALTHSDNTANDRLLTRVGGP -PAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TTRPMPERQKLIQAAAAAVANY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Nostoc sp. 3335mG TaxID=2204170 RepID=A0A318B9S7_9NOSO ---------------FQGRVGIAVRSIDDGWVV-GHAMDQRMPQQSVSKLWVALTAMNAID -EGKLALTTPVRITRSDLTLHQPIAYLMKDGVTTVGDLLRRALTLSDNTANDKLLNLVGGP -VAVRDFIASRGLGNIRFGPGERLLQAAYVADPPDGAGAGAIADALARLHHGMLLKPQSTS -WLLDTMSHTRTGRARLRAALPAGWSVAHKTGTGQTAGFNDVGILTAPDGKSYAVAVLIGD -TARPVRERQQLIQTVVSAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3DEW5_9SPHN -----VSSLNALTRNFGGVAGVSVASVDQGWLI-SSNGERKMPQQSVSKLWVTMTVLDQID -QGKLSLDTPLSFTSEDFTVHQPIAALVKDGQTTVGEVIRRAMQMSDNTCNDKLLRLVGGP -DAVRDFIARRGLGPIRFGPGERLLQAAYVSDPPDGAAPLAIAGALARLKRGELLSPTSTD -WLIATMEAAKTGRARVRAAVPAGWTYAHKTGTGQTAGFNDVGILTAPDGRGYALAVMVGD -TTRPVRERQLLMQQVAAAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Aequorivita sublithincola (strain DSM 14238 / LMG 21431 / ACAM 643 / 9-3) TaxID=746697 RepID=I3YUS1_AEQSU ----LQSKIETIISAKKGTIGVSIIGPKTSDNV-SINGEEMFPMLSTFKFPIALMVLHKVE -VRELSMQQQVFIKKEELLQWSPFREKYPEGNISLEEGINWMVNYSDNNITDILLRLIGGT -DQVEKFLNN---KIFIIKNNEDDMHKDWESQFINKATPSAFTELLKNFSEEKILNKENTA -WLYQAMVGSRTGVNRLKGKLP-NVEIAQRAGTSFTGAINNVGIIELPNKHKIFIAVFIHN -TSEEFEKAEEIIADIAKATYDYy ->[subseq from] serine hydrolase n=1 Tax=Clostridium lundense TaxID=319475 RepID=UPI000481B14F ---ELKEKISDIINENKGDVGVVVKNLNTDSTI-MINEEEVFPSASTIKLVIISTLMKEVS -KGIMKLDDKIVLTNKCKCGGDGILKELNDGKFTLKEIATLMIILSDNTATNILIDLL-SM -EKINEMAKELNLPNTQLRRKMMDSEAA-RMGRENVTTAKDMCHILELIYKGKVVSEEYSD -IILDILKRQQV-GGRLNLYLPEEITIAHKTGDLDK-LEHDVGIVYHQHC-NYIICVLTKN -VE-TNKDGREIIGKVSLQVYN-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 28-62-11 TaxID=1970432 RepID=A0A258RA27_9SPHN ------STIQSLRTQFAGNVGIAVRNIDKGWAV-TANGSTKLPQQSVSKLWVAMAVLDYRD -SGQLTLDDTVTVTREDLTLHQPIAAMVKGDGATVGELLQRALTTSDNTANDRLLRFIGGP -ETVRGFIRRKGLGSISFGPGERLLQSSYVTNPPDGAAPEAIAGALAMLKKGELLSANSTN -YLIATMESARTGKQRLSGAVPAGWRFGHKTGTGQTAGYNDVGILTAPDGQSYALAVMIGD -TPRPVAERQALMQSVVASVVAY- ->[subseq from] Uncharacterized protein n=2 Tax=Parabacteroides johnsonii TaxID=387661 RepID=K5Y3V5_9BACT -------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNLQYPLMSLFKFHVTVAALKKMD -REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI -KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA -FLEETMLNCSSGENKLKAGLPPNVKIGHKTGHSDRTSETDAGVIYLPDGERCYIAVLIKN -SLESDETNARIMADITRVIYH-- ->[subseq from] Beta-lactamase class A n=1 Tax=Parasphingorhabdus marina DSM 22363 TaxID=1123272 RepID=A0A1N6H9H5_9SPHN ---ALEREIFELWRAFPGKTGIAIKRIDQNWEI-GQRANENFPQQSVSKLWVAMTVLHKVD -KGEISLSDSIRIGPDDLTLYQPLAREVARNGKSVYTLLDRALAQSDNTANDALLRHAGGP -DAVNDFIRRSRLGEIRFGPGERLMQSDYLADPIDGATPGAIVNALDKMARGKLLSENSTR -LLQSILTRTRSGPKRLKAGVPPGWGFLHKTGTGQSTGYNDVGIMTAPDGTRYAVAVMLGN -TTAPVPERMQLMQSVTRAVARY- ->[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Calothrix sp. NIES-3974 TaxID=2005462 RepID=A0A1Z4NFC5_9CYAN ---TLKTAIQNLASANNLTPGVFVLDIASGAYV-DLNAGATFSAASTIKIPILIAFFQEVD -AGNIRLDETMTMKQEFIAGGSGDMQKPVGTKYTALEVANKMMTISDNTATNMLIDRLGGI -SSLNQRFQSWGLATTQIRNILPDLEGT------NSTTPKELGQLLTMLNKGNLVSMISRD -RILEIMRQTVR-DTLLPVGVGQDSKIAHKTGDIRS-MIGDAGLVDISNGQRYAIAVMVQR -PDND-PRAERLIGSISRTVYQH- ->[subseq from] Beta-lactamase n=1 Tax=Terriglobus saanensis (strain ATCC BAA-1853 / DSM 23119 / SP1PR4) TaxID=401053 RepID=E8UZF8_TERSS ---SLQSRIATIAATIPAKVSVACSLPNTPLNC-DLNPDANPPMQSVFKFPLAVAVLHRAD -EGKLFLDTPVRYLSVDIISYSPLQDKYPRGNVPLRELITLSVSKSDNTASDILLRILGGP -PVLDAYIHTLGVTGFQVRDNEKSLHATNALQYRNTFSPRAATQLLRLMADRSPLSPASTR -FLNDIMLHATSGPHRIHGDLPEGTSVAHKTGTSGTAATNDIGLITLPNGQRLAIAIFVTD -AHATPEAIEHVMAQIARAAYD-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Sphingomonas jeddahensis TaxID=1915074 RepID=A0A1V2EV52_9SPHN ----LDASIQQMVREFPGVAGVAVRAVDEGWTI-QAGGRRLLPQQSVSKLWVAMTVLDQRD -SGRLKLDDPVSVTAADLTLHQPIASLVKGGQTTVGNLLFRALTQSDNSANDRLLTLVGGP -SAVRAFIERKQLGDIRFGPGERHLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR -LMVSTLEASKTGRARLKAGLAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD -TTRPMRERQQLISAVASTV---- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. EC-HK427 TaxID=2038396 RepID=A0A5E7ZHP9_9SPHN ---ELAANIDRLGEDFGGSLGVAVVDVERDWQT-DWNGTQLLPQQSVSKLWVAFTALRQAD -TGALDLGRDVTLTRADLAVYQPIREEILAAGASVEDLITRAITQSDNTANDAVLNVIGGP -EAVRAELADAQLGDIRFGPGERAMQSRYQDDPVDGASALAIAGALARLERGHLLTRERTR -WLIDVMFATRSGPNRLRAGAPEGFTLAHKTGTGQQSGYNDVGLLYAPDGTAYAIAVMIGE -TQRPTEERMAMMQAVTRAVADY- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115AB0D5 ------------------------------------------------------------- ------------------------------------------ATMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. PP-F2F-A104-K0414 TaxID=2135661 RepID=A0A4R2TW87_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTINDLLTRALTHSDNTANDRLLARVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQAVAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235J1E2_9NOSO --kALEPQIKALMNRYNLKTGMFFLDLDTGDYL-DVGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRGDLVTNGSGTMQERVGKKYTALETITKMITISDNTATNMIIDRLGGV -AKLNQRFRNWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSSQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A2N7QCY1_9BACT --kQLATEIKSVVDSVDGVVGIAIKDLSSGYAF-YLNENEVFPQASSIKIAIWLEVLKQVE -EGKLKLDEFLDLKPQDKVGGGPILVFLGNPSISIRDLCVLMVVLSDNTATNLLIERV-GM -EAVNKRLRSLGLTQTKLQRKMMDLKAA-EEGRENISTPREMLSLMEKIWKGQVLSPELRQ -EFFNLLALPKD--SPLQKVVPEGVVVADKPGELE-AVRCDSGLVFLKKH-PYVIGIMTTY -LSP-QVDGNEIIKKIGALAFHYf ->[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides coprocola DSM 17136 TaxID=470145 RepID=B3JEU5_9BACE ----LESKIKKSIENVPAQVGVAII-INGKDTI-TVNNECHYPLMSVMKYPQALAVLHYLH -QHNQPLSTKIFIPKEALLDYSPLRDKYPGGNMPIDQLLDYTIQKSDNNACDILFNYTGGV -LYTDSYIRSLGINNFSISKTEDDMHKDLAACYENWSTPLEIASLTDMLFSKELFPTEYQN -FLKETMLNCQTGTNRLPAPLDTTARIGHKTGTSDRNGINDVGFILLPDGKRYTIAVLVKD -SKESMADTEKIIAKISEIVYHH- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWA2_61_42 TaxID=1797923 RepID=A0A1F9QGL2_9BACT ---DLTAGLEKTSGAYRGRVGIYLKDLHTGKVW-EYNSDRLFPSASLIKVPIMASVFEKIK -LGAITLDTQIRLTRRGRVGGSGSLKWVRDGTLSVMEIIYKMITESDNTATKMLIDYV-GM -DYLDESFKKLGLTYTNITPEGMSLSSG-RVKKENYTTAREMAGLMERIYAGELVNREASE -FMLDVLKHTKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-FLLAVLTSE -VP-DYTSAKNFIARVAKLTYAYy ->[subseq from] Genome sequencing data, contig C307 n=1 Tax=Microcystis aeruginosa PCC 9808 TaxID=1160284 RepID=I4HTW8_MICAE ---SLNQKLQVLAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. PP-CE-3G-477 TaxID=2135660 RepID=A0A2T5GQV5_9SPHN ----LERVLSMLVAERSGDYGIAALDLRDGSTV-SIRGDTPFPMASTVKLAIAGAYLADVD -QGRRTLGDMIVGRP-------------------AAKALELMIVRSDNQATDQLLAALGGP -VVIQQWLWSHKIAGIRMDRTIAQLLRGHLADSKDVATPIAMVTLLNKLDNGTVLTAQSRN -FLLELMSRCQTGTRRIRALLPAGTRVEDKTGTLD-GITNDVGFITMPDGRRVAIVVFARG -GR----DRQPVIAEVSRAIYDYf ->[subseq from] Serine hydrolase n=2 Tax=Phenylobacterium sp. HYN0004 TaxID=2201350 RepID=A0A2Z3HSX1_9CAUL -----AERLAALDPGFPRPVGIAVMDVGSGWLA-SWQGDQPFPQQSVSKLWVALTIMDQVD -ARRLDLDQPVILTDADRSVNQPVTHLIENGATTVRDLLQRALIQSDNAANDKLMALAGGP -AAVQAFLASRGMSGIRLAEDERRLQSAYVEQPFDGATPAGIVRALAALHRGELLSRTSTD -FILQTLGRVTTGPMRLRGGLPPGWRAAHKTGTGQTFGLNDVGLVTAPDGRTYAVAVLAPQ -APKGSPNRLRVFQSVSAALVEQw ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Cyanobacteria bacterium UBA11049 TaxID=2055787 RepID=A0A3D1P7F7_9CYAN --------VQQLAAQNKLLPGVFFVDLDTGNYM-DLNGETTFSSASTIKFPVLVAFFQDVD -AKKIRLDEQLTVKQELIGGGSGDLQKPVGTKLSALSTAIKMITISDNTATNMLIDRLGGA -KALNQRFSSWGLAVTEIRNPLPDLSGT------NTTSPRDLAQLMAAVEQGNLISVKSRD -RLLDIMRHTAI-VTLLPKGLGEGATIAHKTGDIGS-MVGDVGLVDMPSGKRYVAVAMVKR -PHN-NEQAKELIRSFSRAAYQQf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium xenophagum TaxID=121428 RepID=A0A401IY62_SPHXE ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID -AGALTLEEQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP -TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ -DHKGHETRDRIMAEAARASYDYf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Apibacter TaxID=2630820 RepID=UPI00132C6BC4 --qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -KNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT -KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD -FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARMIANISQVVYNFy ->[subseq from] Serine hydrolase n=2 Tax=unclassified Cyanobacteria (miscellaneous) TaxID=1983111 RepID=A0A3C0NC11_9CYAN ----LEPQVKALMARYSLKTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVSLDETLVMQRRLITGGSGTMQYNSAGTFSARETVTKMITISDNTATNMIIDRLGGI -TKLNQRFRSWGLKDTIIRNWLADLRGT------NTTSSKDMVRLLALLINNQLVSLSSRE -QVLDILRHTTI-KTLLPAGLGPGADIADKTGDIGF-LIGDAGVITMPNGKRYLAGIFVRR -PYKD-SRGRDFIRQVSSLVYNY- ->[subseq from] Beta-lactamase class A n=2 Tax=Oscillatoriales cyanobacterium JSC-12 TaxID=864702 RepID=K8GFU4_9CYAN ----LKTAVQGVVQQYGFTPGVFLIDLDNNNFV-DLSGSASFAAASTIKVPVLIAFFQDVD -AGKIRLDEKLTMRKDLIAPESGDMQYLPPGAFTALETATKMITISDNTATNMLIDRLGGI -QAVNQRFKSWGLSATQITNLLPDLKGT------NTTSPKELASLMVRVSQGELVSLRSRD -RLLDIMRRTVN-NSQLPQGLGEGATIAHKTGDIGT-LIGDVGLVDMPSGKRYAAAVLIKR -AFND-DRAYDLVQKISRTMYQHf ->[subseq from] class A beta-lactamase n=1 Tax=Chryseobacterium sp. YR459 TaxID=1500292 RepID=UPI000648672C ---DLKKTIESIISHKKADVGVSIMGPYQKETI-QINGNKLYPMLSTVKFPIALTVLKKVE -KGELSLQQKLFIKREELLEWSPFKKEHPDGNISLEEALKWIVLYSDNNICDILMRLVGGP -EPVQQLVNS---KDCIIQNNEEDMHKDWESQFVNKITPNEAIRLLETFNNGKILNKKHHL -WLYNAMLNNTAGPKRLKGSLPEYVKVAHRTGTSFTGAINDFGIIELSGSQKIYIAVFVHD -TYEKFENAEAIIADIAKVTYEFy ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A126RJ66_9SPHN -------VVRNLGQSFNGKVGIAVRRVGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRSYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf357 TaxID=1736350 RepID=UPI0009EB8815 ------------------------------------------------------------- ----------------------------------AAKVLELMIVRSDNRAADQVLDSVGGP -AALQQWLSTQKITGIRADRTIAQLLRGHLADSKDVATPVAMVTLLQKLDSGTVLTAQSRT -FLFGLMSRCATGTRRIRALLPAGTPVEDKTGTLD-GVTNDVGFITMPDGRRVAVAVFARG -GR----DHQPVIAQVSRAIYDRf ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter donghaensis TaxID=267135 RepID=UPI00093EB6BE ---TFEQRIAELANPALGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKIAIAATYLEMVE -QGRYTLTSEFPLLLPVRSASSAKAPVRPGQYMPAIDLIEIMITRSSNPATDALLAAVGGP -QAVNSWMARKGLAPFSLNRDIATLVRANHIDSRDAATPRAMVRLLAGLYRGEYLSDQSRQ -VILGAMSRTVTGKRRIPANMPLEARVSHKTGSLSN-TSSDIGLIECPDGRVIAVAIYVTG -QG-TKLAREERIAAIARALYDGf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A350KUF0_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LVLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI00130A9DDA ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -EALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-LLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8CKD9_9BACL ---SLQEKLEHVLSESSATFGVVVKHLGTGEEA-RVRPEQYFQMASTFKVPILATLFRDID -EGTCSLEQRFRLTEDDLVPGSGVLKEFLPGAVALRDLATLMIIVSDNLATDKILELI-GA -ERVDAYMKELGLQNISIKQSCWELLSFQPTPENNVTTPADMNQLLEWIGTGQLSSQAASD -GILDIMKRQQL-RNRIPYLLPDQTVVASKSGTVGH-VVNDVGIVYLPEEKGAFTITALSF -GHASTKEGERMIARLAQTAYEHf ->[subseq from] Putative beta-lactamase class A n=1 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=A0A087NIN7_9SPHN ---TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD -RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR -LLLTVMGEAKTGPQRIKGGVPPGWAYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A2Z4WTF0_ECOLX ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGQ---------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Microcystis aeruginosa TaxID=1126 RepID=UPI00130D1C3C ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-LLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Microcystis aeruginosa NIES-2549 TaxID=1641812 RepID=A0A0F6U5V0_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFSAASTIKIPILVAFFEDVD -AGKIRLDEPLVASKDVMASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-LLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf357 TaxID=1736350 RepID=A0A0Q5RBJ1_9SPHN ---ALVANVTTLGTNFQGKVGIAVHSIDQGWTV-QSNGETRMPQQSVSKLWVAMTVLDFRD -AGRLKLDDPVTIRREDLTLHQPVAALVKGDGTTVGELLQRALTMSDNTCNDRLLQYVGGP -AAVRAFIARKNLGDIRFGPGERLLQSRYVANPPDGAAPLAIAGALAKLKQGKLLSASSTD -YLIGTMESSRTGKQRMHGAVPPGWSFGHKTGTGQTAGYNDVGVLMAPDGRSYSLAVMIGD -TPRPIPERQALMQAVVAAVVM-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. PP-CC-3A-396 TaxID=2135655 RepID=A0A4R2U6E2_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTINDLLTRALTHSDNTANDRLLARVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQAAAAAVAKY- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_MB_S_20031200_S102 TaxID=2486254 RepID=A0A552EKF9_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFSGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVATKDVLASGSGDMQYGLNKTYTALETATKMNVISDNTATNMLIKRMGGK -KALNQRFQAWGLTSTVINNPLPDLEGT------NTTSPRDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V567_9BACT -------------------------------------------------VMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQQA -QLVTWMKGNTTGAASIQAGLPASWVV---------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Mn802worker TaxID=629773 RepID=UPI00035D02FB ---RLRAEVDRLIAGFPGKAGAAIRAVDDGWTV-QRGGALSMPQQSVSKLWVALTVLSQRD -AGKLRLDDPVLVTTNDLTLHQPIASLVRGEGTTVMGLLTRALTQSDNTANDRLLTLVGGP -SAVRAFIAEHQLGAIRFGPGERLLQSRYIDNPPDGAAPLAIADALARLARGDLLSETSTR -VMLDTMGASITGRARLRAALPAGWKIAHKTGTGQNAGFNDVGLLTAPDGKRYAVAVMIGD -TRAPMRERQQLIQNVAAAL---- ->[subseq from] Serine hydrolase n=1 Tax=Microcystis aeruginosa Ma_MB_F_20061100_S20D TaxID=2486253 RepID=A0A552EYS3_MICAE ---SLNQKLQALAVKYKLQAGALFIDLDNGAYA-NFRGDTIFAAASTIKIPILVAFFEDVD -AGKIRLDETLVASKDVLASGSGDMQYGVNKTYTALETATKMNVISDNTATNMLIKRMGGK -KVLNQRFQAWGLTSTVINNPLPDLEGT------NTTSPKDLVTILGKVNQGELLSLRSRD -RLLNIMQETRT-RTLLPQGIEKSADIAHKTGDIGS-MLADAGIIDMPNGKRYLGAVMVKR -PHND-SNARTLIQQISRTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=A0A0F3JZ35_9GAMM ---TLQAHLQAVADQAPGTLGILVMDPATGGTV-TVNDHRPYLMMSVFKAPIAAAVLASVD -AGTLSLDKKVALTPADIVEGSAVPGEALKAGFSIDELLHAAVTQSDNTAVDALLRVLGGG -KAATAFLTGKGVQGIRIDMGERELGAAVLASQVNSATLHGAAAFLRKLQAGELVSPASTQ -KLLGLMTAQVI-PNRLRGGLPAGYQLADKTGTSGTRAFNDIGIVTAPGGGKRIVVVFLAE -ARATPEQATKWFAEIGHEVT--- ->[subseq from] serine hydrolase n=1 Tax=filamentous cyanobacterium ESFC-1 TaxID=1128427 RepID=UPI0004AF6E9A ----LKQKIEALAAQYDLEVGALLVDLDTGLYV-NIRGEESFAAASTIKLPILIAFFQAID -ANQVSLDEKLTMRPDLIAGEAGTMQQQPGTQFTALETMKKMIEISDNTATNIAIDRLGGA -TVLNQRFQDWGLQATVIQNLLPDVEGT------NTTSPKDLAELMAMMNQGEIMSSRSRD -RVLDIMQNVQT-NSLLRQGIGQEATIAHKTGNIGS-LVADAGIIDTPTGKRYLAVVMVKR -PHND-PKAIELIQEISRTAYEYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C5Y5U0_9BACE --qELYSNINHFIAQQKAEIGVAIIA-EGKDTL-TIGNNHHYPLMSVFKLHQALAVGNYCE -KHRISFDTLLTVSKTDLKRYSPLRDQHPNGGFSLKQLMQYTLHLSDNNACDILFRFMGGP -DVTDRYIRSLGIKDFSVQHTEEDMHRNLNLCYQNWSTPLATAEVIEALLTRPLFDKEHQE -FIKKSLITCQTGKSRIVRPLQKNVIVGHKTGTGDYNAINDAGFIVFPDGRRYTLVVFVKN -SQENPEHTEVIIAHISEMVYQAf ->[subseq from] serine hydrolase n=1 Tax=Luteibacter yeojuensis TaxID=345309 RepID=UPI000ACB8784 ---TLQAHLQAVADQAPGTLGILVMDPATGGTV-TVNDHRPYLMMSVFKAPIAAAVLASVD -AGTLSLDKKVALTPADIVEGSAVPGEALKAGFSIDELLHAAVTQSDNTAVDALLRVLGGG -KAATAFLTGKGVQGIRIDMGERELGAAVLASQVNSATLHGAAAFLRKLQAGELVSPASTQ -KLLGLMTAQVI-PNRLRGGLPAGYQLADKTGTSGTRAFNDIGIVTAPGGGKRIVVVFLAE -ARATPEQATKWFAEIGHEVT--- ->[subseq from] serine hydrolase n=1 Tax=unclassified Erythrobacter TaxID=2633097 RepID=UPI000ACF5E06 -haALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRSGDLTVHQPIRDIHRDGSADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LVLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAVAVMIAR -TREPTPVRMEMMQEVVRAIVR-- ->[subseq from] serine hydrolase n=1 Tax=Geitlerinema sp. PCC 7105 TaxID=102127 RepID=UPI0003483B50 ---ALKERLQQVATEYGLTPGVAIVEVATGDYV-RLSDTMSFSAASTIKVPILVAFFRAVD -AGTVRLDEVLTMEESHVAEGSGYMQYAPGTRYSVLEVASSMIIDSDNTATNMLVDRLGGA -KVLNEQFREWGLTETTIRNPLPDLEGT------NTTTPQELAKLLGQLERGELVSMRSRD -RMMRIMSQTAN-DALLPQGLGEGAFVAHKTGNLRS-VLADAGAIDLPNGKRYLMVAIVKR -PDED-DRAADLIRQMSATAYDYf ->[subseq from] Class A beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A249MSY8_9SPHN ---RLIAQFQRFASLTDGTVGIVVRDLGTGETL-SLNGDTLFPMASAYKVAVAGRIFAMID -AGALTLEEQLA---------------SPAGPVSVATLLDLMLTRSDNDATDLLVARAGGP -TAVHQWVAGLGIRGLRVDSNTADLLYAFARDPRDTATPTAMTDLVAAIRTGKALSGRSTV -ALLSIMERCRTGKARLPGMLPPGTLVAHKTGSLN-GTGNDTGVISLPDGRLFAITVFVMQ -DHKGHATRDRIMAEAARASYDYf ->[subseq from] Serine hydrolase n=2 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9EAZ5_9BACT --qKLEAAIQDIDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ -QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM -ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMMLLEDLYRAKILNKQMTD -DFFELLSIHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNR-PFVISVMTTY -LHRE-KDGGEAIIRIATAAYQMf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4Q3ABN4_9SPHN ----LTATVDALARDFGGVVGISVRSLEWGWQV-DANGNRRMPQQSVSKLWVAMTVLDARD -KGRLTLDDPVELTREHLTLHQPIASLVVRDGTTVRELLLRAMQTSDNTANDRLLTLVGGP -QAVRAFIADRALGEIRFGPGERLLQASYVADPVDGAAPSAIALALARLKAGELLSASSTS -FLTNVMSGTRTGKARLRAAVPVGWVLAHKTGTGQTAGFNDIGILTAPDGKAYSIAVMIGD -TPRPVRERQQLMQAVVASVVA-- ->[subseq from] Beta-lactamase class A VEB n=1 Tax=Parabacteroides chartae TaxID=1037355 RepID=A0A1T5BBF4_9BACT ---ELKKEIEIIVGGKDLKLGFALYDFSTGKSI-SINGNDRYPMQSVFKFPIGVALLDCVS -RGEFALSDSVTLTKADLLPWSPIRERWPEGVLPLVSVMTYMVAHSDNSATDFLIHKIGGV -ARIQDIVNRLGAKKINIRNNEAEIQGSWSVQFDNWTTPNAMVDFLRLMNDGKLLDKANTA -VLWEIMASASS--GSVNRLVPKTVTFARKTGYSGANAQNDVGIIELEDGRRVAYAIFLTD -STLGTDAGYDILAQIGKAIWKAy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas faecihominis TaxID=1472416 RepID=UPI000F57FB0E --qGLEEQLRKVIANKKAQIGIAVI-INGKDTI-TINNDERYPMMSVFKLHQALAVADYCE -KKGLSFDTPIYIRKADLKTYSPLRDLYPNGELPIKKLLEYTLHLSDNNACDILFQQTGGT -EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG -FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD -SEESEAATARIIADISKTVYRH- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0M3AXX1_9SPHN -------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMAFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Dyella sp. 333MFSha TaxID=1798240 RepID=A0A1G7M2J6_9GAMM ---TLQASLQKLADQAPAKFGIIVVDLDGSAAA-KVNDDRAYMLMSTFKAPVSAAVLHQVD -TGKLRLDQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAVTQSDNTAVDALLKLVGGG -QVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK -RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGKRAVVGAFLRD -TTSTDEQRAAWFKELGTVVSK-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium bisphenolivorans TaxID=1335760 RepID=UPI0003A412FC ------SVIRNLGQSFNGKVGIAVRRVGSDWTV-AWNGTSLFPQQSVSKLWVSMAFLDAVD -RGKIRLTDTTTITRKDLTLHQPTAALVGSSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRSYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVEALAKLKEGDMLSSASAQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTESIPSRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf17 TaxID=1735683 RepID=A0A0Q4FPS4_9SPHN --eALSARIDALARAFAGKAGIAIRAVDQGWSV-EAGGRQRLPQQSVSKLWVALTLMDLRD -QGRASLDTPITVRPQDLTLHQPIAMLVKGSGTTVGDLMVRALTHSDNTANDRLLNYVGGP -SAVRAMIERKRLGDIRFGPGERALQSAYIANPPDGAAPLAIADALARLARGELLSEGSTR -ILLDTMGRSVTGRARLRAALPPGWIIAHKTGTGQNAGFNDVGLLTAPDGNRYAIAVMIGD -TLRPIQERQQLIQAVAGAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=Luteibacter pinisoli TaxID=2589080 RepID=A0A4Y5Z2R4_9GAMM ---HLQAALQKVADQAPGTLGVLVMDPAAGQSV-SVNAGRPYLMMSVFKAPIAAAVLSQVG -AGTLTLDRTVHLGPADVVDGSAVPGASLKAGVSVDELLHAAVTQSDNTAVDALLRLLGGS -PVATRFLASKGVQGIRIDMGEGELARAVLASHVDSSTLEGAGAFLRKLQAGELLSAGSTQ -KLLGMMSAQVI-PNRIRGGLPAGYQLADKTGTSGTRAFNDIGIITAPNGQKRVVVVFLAN -ARATPEQATKWFAEIGRLTA--- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Parabacteroides sp. TaxID=1869337 RepID=A0A354WXV1_9BACT --eTLGHQLRQVINGKAATVGVAVI-FKGSELI-SINNMYRYPMMSTYKFHQALSVIDYLH -KHNENLATEILVKKSDLLAHSPLRDANPNGNITIGDLLKYSLIDSDNNACDILFKHIGGV -QVTEKYIHGLGIKDVAISQTEAKMMESENNCMLNWTKPSAAVLLLETFLQNQMFNKNEIL -FLERAMADCKTGNDKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVLPNGQYYTIAVFVMN -SRETDKENAKLMADISRTVYEYf ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. ba1 TaxID=1522072 RepID=UPI0005685747 ---TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD -RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR -LLLTVMGEAKTGPQRIKGGVPPGWAYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis (strain ATCC 27551) TaxID=336203 RepID=A0A292ZHM8_SPHSA ------SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas adhaesiva TaxID=28212 RepID=A0A2A4I652_9SPHN ---ALQARVAELVRAFPGKAGAAIRSVDDGWVV-GQGGDLSLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVSRDDLTLHQPIASLVKGEGTTLSGLLTRALTQSDNTANDRLLTYVGGP -TAVRRFLASKELTGIRFGPGERLLQSRYIDNPPDGASPNGITAALARLARGELLTETSTR -ILLDTMAASRTGHARLRAATPTGWQLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TTAPMRDRQKLIQDVCAAL---- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter sp. B2912 TaxID=2656763 RepID=UPI001369B657 --kSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -NNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT -KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFINKDIFCKNYKD -FLFQAMTESETGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARIIADISQVVYNFy ->[subseq from] Serine hydrolase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A356THR2_9DELT ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LVLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9BV01_9BACT --qKLAATLNDVDGKLDGVLAVAVLDLSTGQKY-LLHADEVMPTASSIKIAILAELYRQAQ -QGKVKLTDFYTLQQSDMVGGSGITSVLTPGMLTLRDVAGLMISVSDNSATNVIIDRV-GM -ENVNALLDSLGLTHTRLRRKMMDIKAA-AEGRENVATPREMMLLLENLYRGKVLNKPMTE -DFFNLLSVHKE--SYIPRNLPEDVRVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTTY -LRRE-RDGGEAITKISDAAYQMf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=2 Tax=Pirellula sp. SH-Sr6A TaxID=1632865 RepID=A0A142Y5M6_9BACT --aQLASQFDPLIRNHQGEVAVAIKNLDTGELY-QHNETTVMPTASLIKFPVLVELYRQVD -AGNLRLDRLVTLQDSDKVPGSGILTDHFQSGIPLETIARLMIRYSDNTATNLVLDQI-GM -ENTSKTMLQLGFRETRLHSKVFRRDTRSQKYGLGSTTAAEMLGLLELLHAKMLVSEKASE -QMLTHLASCED-DSKLVRDLPKAVKSFHKTGSVND-VRTDAGLFQTPKGT-LAIVVLTAK -NQGNANAAELLCAKIGSTAYEWf ->[subseq from] Beta-lactamase n=1 Tax=Anabaena cylindrica (strain ATCC 27899 / PCC 7122) TaxID=272123 RepID=K9ZDS1_ANACC ----LEPQIKALMNRYSLQTGMFFLDLDNGDYL-DIGGDRVFPAASTIKLPILLAFFQELD -AGRVSLDDKLTMRRDLVTNGSGVMQERVGKKYTALETITKMIVISDNTATNMIIDRLGGA -AKLNGRFRSWGLKNTVIRHLLGDFKGT------NTTSSQDMARALALLVNDKLVSSQSKE -QALDILRHTKT-RTLLPAGLGKGAIIAHKTGDIGF-LIGNAGFVTMPNGKHYLAAIFVKR -PYKD-VRGREFIREVSRLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Ag1 TaxID=1642949 RepID=A0A0M2LTS5_9SPHN ---ALDASIQQLVREFPGIAGVAVRAVDEDWTI-EAGGRRLLPQQSVSKLWVAMTVLDQRD -NGRLKLDDPVSVTASDLTLHQPVAYLVKGGTTTVGNLLFRALTQSDNTANDRLLTLVGGP -RAVNAFIERKRLGDIRFGPGERLLQAAYIDNPPDGAAPLAIADALSRLARGELLSETSTR -LMISTLESSRTGRARLKAGIAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD -TTRPMRERQQLIQAVAASV---- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc minutum NIES-26 TaxID=1844469 RepID=A0A367QYW6_9NOSO ----LEPQIKTLMARYGLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLDEMLTMRRDLVTNGSGVMQQRVGKKYTALETINKMVTISDNTATNMIIDRLGGA -ARLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALLVNDKLVSSTSKE -QALDILRRTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPSGKRYLAAIFVKR -PYKD-VRGRDFIRQVSHLVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium wenxiniae (strain DSM 21828 / JZ-1) TaxID=595605 RepID=A0A562KDC6_SPHWJ --eRLLAQFQSFAALSDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILSMAD -AGVLALQDQVPLGPALL-----------AKARSVHDLIDLMLTHSDNDATDALVARAGGP -AAVDGWVKALGVKALRVDSDTAHLLYAFTLDPRDTATPRAMNALLAAIQLGKALKPASTV -YLLGMMERCHTGKARLKGMLPPGARIAHKTGSLN-GYGGDVGIVTLSDGRMFAISVFVMK -DYRGRETRDRIMAQAARAAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0C5XJA7_SPHYB ------SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AE3 TaxID=2594473 RepID=A0A516IRI8_9SPHN ---ELREQISSLSRAFPGIAGVSVMSIKDGWQI-GYNDRKLFPQQSCSKLWVAITALDAVD -RGRVSLNDRVTIGRDDLTLHQPIRTKVLGNGTTLGALLQSAITESDNTANDKLMRSVGGP -LAVRDMIDSKRLGSIRFYEGERALQSRYIADPYDGAAPQAVTQSLARLKRGELLSPASTQ -RLLSTMASTKTGALRVRAAMKPGWKWSHKTGTGQVGGINDIGILTAPDGTAYAMAIMTVP -SK-SDGAAQEFMQKIARAVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. NAP1 TaxID=237727 RepID=A3WE64_9SPHN ---RFEAMLRQIEGESNGTLGVELFDVSTGHSV-GINRDRRFGHCSSFKLSLAAMVLASDS -LGIVDADKRVMWSEDDLMAVSPFTTRRLIEGATLRELAEATQKFSDNAAANILLREYGGP -AALTAFWSGIGDNVSRLDRYEPALNNVPVAEYRDTTTPAAMARTVAALAYGEILPDEDRA -TLRQWMIDTPTGVRRVRAGLHEELVGGDKTGTSLESLYVDIGFVEPPADK---------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas ginsenosidimutans TaxID=862134 RepID=A0A2A4HXQ4_9SPHN ---ALQGRVSELIRAFPGKAGAAIRSVDEGWVV-GQGGDLSLPQQSVSKLWVAMTVLAQRD -AGRLKLDEQVLVTRDDLTLHQPIAALVKGEGTTLSGLLTRALTQSDNTANDRLLTYVGGP -AAVRRFLASKELTGIRFGPGERLLQSRYIDNPPDGASPNGITAALARLARGELLTETSTR -ILLDTMAASRTGHARLRAATPAGWQLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TTAPMRDRQKLIQDVCAAL---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=D2WSB1_KLEPN ------------------------------------------------------------- -------------------------EKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLR- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf198 TaxID=1736299 RepID=A0A0Q5UYQ5_9SPHN ----LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQQAAAAVAH-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLG TaxID=1985880 RepID=A0A430DKW1_9SPHN ---ALDASIQQLVREFPGIAGVAVRAVDEDWTI-EAGGRRLLPQQSVSKLWVAMTVLDQRD -NGRLKLDDPVSVTASDLTLHQPVAYLVKGGTTTVGNLLFRALTQSDNTANDRLLTLVGGP -RAVNAFIERKRLGDIRFGPGERLLQAAYIDNPPDGAAPLAIADALSRLARGELLSETSTR -LMISTLESSRTGRARLKAGIAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD -TTRPMRERQQLIQAVAASV---- ->[subseq from] serine hydrolase n=1 Tax=Porphyrobacter sp. AAP82 TaxID=1248917 RepID=UPI0002D91EA4 ---TFEQRIADLANPALGRIGVAAVDLATGEEV-MVLGDQLFPMASTSKVAIAATYLEMVE -QGRFTLTSEFPLMLPVPSARFSTAKAPVRAGMPAIDLIELMITRSSNPATDALLAAVGGP -QAVNSWVQRKGLAPFSINRDIATLVRANFIDTRDAATPRAMVRLLAGLYRGEYLSEQSRQ -VILGAMSRTVTGKRRIPANIPLEARVSHKTGSLSN-TSSDIGIIECPDGRVIAVAIYATG -QGGK-LAREERIAAIARAVYDGf ->[subseq from] HGC-1 beta-lactamase n=1 Tax=Bacteroides sp. CAG:875 TaxID=1262752 RepID=R7AAN9_9BACE ----LYSNINHFIAQQKAEIGVAIIA-EGKDTL-TIGNNHHYPLMSVFKLHQALAVGNYCE -KHRISFDTLLTVSKTDLKRYSPLRDQHPNGEFSLKQLLQYTLHLSDNNACDILFRFMGGP -DVTDRYIRSLGIKDFSVQHTEEDMHRNLNLCYQNWSTPLATAEVIEALFTRPLFDKEHQE -FIKKSLITCQTGKSRIVRPLQKNVIVGHKTGTGDYNAINDAGFVLFPDGRRYTLVVFVKN -SQENPEHTEAIIAHISEMVYQAf ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. RSMS TaxID=520734 RepID=UPI0010F8A18F ------SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium J055 TaxID=2420338 RepID=A0A3M1SQG4_9CYAN ---DLQAEVEKMAAQNELNPGVLFVDLETGGYL-NLNDTHVFSAASTIKIPILVAFFQAID -EGTIRLDEELTLKPEQIVPEAGFMQYDPPGTYTALEVATAAIVASDNTATNMLIDRLGGT -ETLNQKFRSWGLTQTVLHNALPDLGGT------NTTSPQDLAKLILAVDRGKVISLPSRD -RLLEIMKETEN-DSLLPQGLGEGASIAHKTGTINS-ILADAGLVALPTGKRYIAVVMVER -TDGD-ERAGDLIRQISTVAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus subsp. aureus 71193 TaxID=1155084 RepID=A0A0E0VRK8_STAA5 ----------------------------------------------------------QVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -TKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Class A beta-lactamase n=1 Tax=Butyricimonas synergistica TaxID=544644 RepID=A0A1U7L984_9BACT --qGLEEQLRKVIANKKAQIGIAAI-INGKDTI-TINNDERYPMMSVFKLHQALAVADYCE -KKGLSFDTPIYIRKADLKTYSPLRDLYPNGELPIKKLLEYTLHLSDNNACDILFQQTGGT -EATDHYIRSLGMRHFAIKATEDEMHQDKNKCYQNWSTPLETARIIELLLNVRLFDDEYQG -FIKTTMMSCETGKDRLARPLQNKAIIGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD -SEESEAATARIIADISKTVYRH- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium fuliginis ATCC 27551 TaxID=1208342 RepID=A0A5B8CEN5_SPHSA ------SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRSYLARRYIRDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V585_9BACT -------------------------------------------------VMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPGDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1AW48_KLEPN ------------------------------------------------------------- ------------------------SEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYL-- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf198 TaxID=1736299 RepID=UPI000AE6C8A9 ----LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQQAAAAVAH-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf242 TaxID=1736304 RepID=A0A0Q4R8F1_9SPHN ----LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQQAAAAVAH-- ->[subseq from] Beta-lactamase class A n=1 Tax=Microcoleus sp. PCC 7113 TaxID=1173027 RepID=K9WJP5_9CYAN ----LEPQIKALMARYSLQTGMFFLDLDTGNYL-DISGDRVFPAASTIKLPILIAFFQALD -EGKVNLNETLVMRRDLMTNGSGTMQYRAGKKFSIRETVTKMITISDNTATNMIIDRLGGR -AKLNQRFQSWGLKDTVIRNMLGDFKGT------NTTSPKDLVRLLTLVANQKLLAPSSRE -QALEILRNTKT-RTLLPAGLAPGAEIAHKTGDIGF-LIGDAGMIEMPNGKRYLAGIFVRR -PYKD-VRGRDFIRQVSQTVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. WZY 27 TaxID=2283317 RepID=A0A369VT65_9SPHN ----LVETIGDLGRNFGGKVGIAVRAVDGGWSA-DSNGSLLLPQQSVSKLWVAMTVLDQVD -RGRLSLDTPLVVRSEDLTVHQPMAMLVKGDGTDVRELLRRALTTSDNTANDKLLQTVGGP -EAVRGFIQRKGLGAIGFGPGERLLQAAYVDNPPDGAAPSAIAFALAALARGELLSPASTR -YLLSTMEASRTGPQRLRGAVPASWTSAHKTGTGQTAGYNDVGLLTAPDGTRYAVAVMIGD -TRRSIPQRQALMQAVAAAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium SG_bin5 TaxID=1827382 RepID=A0A1W9H2C1_9PROT ----LQNSVQLLVRQFPGKVGIAVSSVDQGWLL-SANGDVRLPQQSVSKLWVAMTVLDGID -AGRFTLDTPVKVTREDLTLHQPIAAMVKPGKTTVGDLLQRALTQSDNTANDRLLRFVGGP -EAVRGFIAKKGLGNIRFGPGERLLQAAYVADPPDGAAPAAIATALARLKKGELLRAFTTG -YLIATMESSKTGKMRLRGAVPPGWSFGHKTGTGQTAGYNDVGILTAPDGRSYTLAVMIGD -TRRPIAERQALMQQVVASIVAY- ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides sp. OF04-15BH TaxID=2292281 RepID=A0A416GGM6_9BACE --qDLKQSILHYLTDKQAEVGVAVI-FNGTDTL-TVNNDNRYPLMSVVKFHQALAVADTLT -ALSETVDHKVLVTPEDLKPYSPMRDRYPQGNLPLRTLLEYTLQQSDNNACDLLFRLYGGP -QATDRYIRSLGLTDFAVQVTEDDMHRDTQTCYDNWSTPLEAVRLLEIFLKKPLFAQPIQE -FLKTTLMECEIGTDRLPAPLATGARIGHKTGTSDQDAINDMGFVLLPDGRYYTIAVFVKH -SRESAENTARIIADISRLVYSSf ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A4R2S117_9SPHN ----LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKLRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQQAAAAVAH-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Altererythrobacter namhicola TaxID=645517 RepID=A0A1C7D924_9SPHN --qDLSEQIAALGEGFDGEAGLAFRDNQTGRII-HYQGDALYPQQSVSKLWVAMAALAQAS -AGELDLQDSVTIRRADLTVYQPIRSIVRQQGTDYADLLSRALTRSDNTANDVLLRRVGGP -EAVQAWLNGAGLGAIRFGTDERTKQSGYLSAPMDGASPVLMAVALGRLAEGNLLDTVSTE -LLLSTLEETRSGPKRLKGGLPDGWTIAHKTGTGQQSGYNDVGILTAPDGRTYTVVAMIRR -TSAPNGQRMELMQELVRAVG--- ->[subseq from] CepA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SY47_9BACT --eTLGEQLRQVIQGKAATVGVAVIF-NGSELV-SVNNMYRYPMMSTYKFHQALSVVDYLH -KHDKNLATEILVKKSDLLAHSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP -LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL -FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN -SRETDQENAKIMADISRTVYEYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. 20006FA TaxID=2056888 RepID=A0A197BT17_9SPHN ------SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. SA916 TaxID=1851207 RepID=A0A2K0XW28_9SPHN ------SVIRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNAGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] CepA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SVM0_9BACT --eTLGEQLRQVIQGKAATVGVAVIF-NGSELV-SVNNMYRYPMMSTYKFHQALSVVDYLH -KHDKNLATEILVKKSDLLAHSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP -LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL -FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN -SRETDQENAKIMADISRTVYEYf ->[subseq from] HGE-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0F1_9ZZZZ ----LESRLRRIIRLSNTDVGVAVISGSRNWAV----GNRKRPLLSVFKFFIAVQTLRQME -QTGTALNAKLTVEENMTDAYSPMLKKHPRRPISLAELLEYMIAESDNNAADILLKYSGGT -GQLEKFLHDLGFSGIDIRVNEKQMNQKAENQYLNQAAPSDVAGLIKLVLEKDVLSAEHRK -FLSDIMLKTSTGTDKIKQGLPPGVMFGHKTGSSSRTADNDAGFVTLTNGRTYYIAVMITE -SKLDDRANAALAAQISQTVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas lenta TaxID=1141887 RepID=A0A2A2SG65_9SPHN ---ALIAAVEEAVRGFDGLAGAAVRAVDDGWTV-EANGRRPMPQQSVSKLWVALTLMEQRD -QGRVRLDDPITITRGDLTLHQPIAYLVAKNGTTVGDLLNRALTQSDNTANDRLLTLVGGP -GAVRDFIANKRLGEIRFGPGERLLQARYVDNPPDGAAPLAIADALARLARGELLSESSTR -IMLDTMGRTVTGRARLRAAMPVGWKLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TRASTTARQQLIQTVARAVT--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=A0A0Q4L6K5_9SPHN ---SLVNAISQLQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP -SAVRGMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQKLIQNAAAAVANY- ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QM44_9SPHN ---ALEEEIAALAAGFDGEAGLAVQDVATGRIL-HAQGDALYPQQSVSKFWVALAALNEAD -EGRFDLSETVTLRREDLTLHQPIREIVRTQGTDYGDLFDRALTRSDNTANDRILRRIGGP -ETVQEFIDDADLAGIRFGTDERTKQSAYLADPVDGASPIAMAHALGQLARGELLSSVSTE -LLLSTLEQTRSGPRRLKGGVPPGWTIAHKTGTGQQSGYNDIGIVTSPAGHEYAVVAMIRR -TGAPVPARMEMMQELVRAVVR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WPQ5_9BACT ---DLTKQIAALCNDAQGEIGVTVIHVESGRTV-EFEGEKKLPLYSVFKLPLAVEVLKRVE -EKKISLDQKLHVDPADVAPGSQFNADLWRKPKTVAELLEFSIVRSDNTSSDKLLQLVVGP -AVVTERMRGLGFPQIDIVSTVREYAT--SRDKPNLATTANLARLLNRLQKGELLEPAHLS -LLLGFMERARTGERRLRASLPTGTPVAEKTGSGAD-STNDVGLITLPDGGHLAMAVLIHN -SKLTAEAQERLIAELAR------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X6Y1_9BACT ---HLAARYEQIAAQAKGRVGAASVVLEGGEET-CIRCDEHFPMQSVYKFPIAMAVLARVD -AGELKLDQKVAVSKNEYLAVSQLRDRSRDKDVELRELLELAVVKSDGTASDVLMRLLNGA -KEVMRFLASIGIDATSINDPEMALQKDWQVQYRNWMSPRGALKLLRAFHEGKGLSKQSHA -LLRDMLERSIRGEKRLKGLLPKETVMAHKTGTSGTAATNDIGIITLPNGKHLAVAVFVSD -SKGDQPMREGAIAALARLAWD-- ->[subseq from] Serine hydrolase n=1 Tax=Arthrospira sp. PLM2.Bin9 TaxID=2599626 RepID=A0A5Q4H9I8_9CYAN --kDLKNQLESVAAASDVSPALMFLDLNTGGYV-GLREQSIVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALETATKMMTISDNTATNMIIDRLGGF -QVLNQRFRSWGLTDTMARNPLPDIEGT------NKTTPRDMVNLFSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVGNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAER -TNG-NQAAESMIQKMSRQVYEY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium estronivorans TaxID=1577690 RepID=UPI00123951A2 ------AVVRNLGQSFHGKVGIAVRRVGSDWTV-AWNGNSLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITRKDLTLHQPSAAMVGANGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGYLARRFIKDIRFGPGERLLQSNYLASPPDGAAPSSIVEALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTESIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. RF31YmG TaxID=1932668 RepID=A0A252CY76_9NOSO --kALEPQIKALMNRYSLTTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGEMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -GKLNQRFRTWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSDSSKE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. Chol11 TaxID=1385763 RepID=UPI000BE4539D -------VVRNLGQSFNGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD -RGKIRLTDTTTITRKDLTLHQPTAALVGTSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRTIKDVRFGPGERLLQSNYLSNPPDGAAPSSIVKALAKLKEGEMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPPGWKYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. EO9 TaxID=2304063 RepID=A0A418YSV8_9SPHN ------SVVRNLGQNFRGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRLTDTTTITRNDLTLHQPTAAMVGTSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIRDIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKQGEMLSSASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVGIPERWALMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AAP5 TaxID=1523415 RepID=A0A4P6XBA9_9SPHN ---ALVANVAMLARQFDGRVGIAVRSIERGWSV-DTGGDQLLPQQSVSKLWVAMTVLDYRD -RGRLRLTDPVTLYRDDITLHQPIAALIKGDQTTVGELLQRALTMSDNTANDRLLRYVGGP -NAVRDFIQRKGLGDIRFGPGERLLQSRYVADPPDGAAPMAIAGALARLKRGDLLSPESTR -YLIGTMESSHTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGSSYAIAIMIGD -TPRPIPARQALMQAVVASVVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Myroides profundi TaxID=480520 RepID=A0A0B5RJE9_9FLAO -hqELNNQINKVINTKNATVGVAIIY-DAKDTL-TVNNNHKYPTMSVYKFFQALNILDYMD -KHNISLDTEIFIKKEDLQEYSPLRDKRPMGDISLGELIQYAASHSDNNVSNLFFKSLIGP -KMTDLYFRTLGIKEFEIVSSEEEMSLDFNNQYQNWITPLEATRILEMFRKEELLSPKYNN -FLRQAMIDTKSGQDKVKALLPKNTLVVHKTGMSFRAADNDLAIVYLPNGKQFSIAVLVMD -SKESDQTNAAIIAEIAKLTYDYf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 106C TaxID=1932667 RepID=A0A252DQR4_9NOSO --kALEPQIKALMNRYSLTTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGEMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -GKLNQRFRTWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSDSSKE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFITMPNGKRYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. XS-10 TaxID=2599297 RepID=A0A518RLK8_9SPHN ---ALTATIASLAKEFGGVVGISVRSLDWGWQV-DANGQRPMPQQSVSKLWVAMTVLDARD -KGRLTLDDPVTVTRDNLTLHQPIASLVVKNGTTVRELLLRAMQSSDNTANDRLLTLVGGP -QAVRAFIAEKGLGAIRFGPGERLLQAAYIADPPDGASSSAIALALARLKAGELLSPASSN -FLINVMQGARTGRARIKGATPPDWKWGHKTGTGQTAGFNDVGVLTAPDGKAYSIAVMIGD -TSRPVRERQELMQAVVTSVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9XB95_9BACT -------------------MGVAILDLTGGQKF-LLHADDVFPQASSIKIAVLAELYHQAQ -QGKLKLADLYTMQQSDLVPDSDIMGGLTPAIITLRDLATMMVAVSDNSATNVLIDRV-GM -ENVNAFLDSLGLTHTRLRRKMMDLKAAG-EGRENIATPREMMVLLEALYRGKVLNKEMTD -DFFKMLSTHK--DSWMPRDLPEDTRVANKPGSLE-GVRNDSGIVFAKNR-PFVICVMTTY -LR-DEREGEKAITRIGLAAYRMf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. Ant17 TaxID=1461752 RepID=A0A013VN19_9SPHN ------STIRNLGQGFRGKVGIAVRRVDADWTV-AWNGNALFPQQSVSKLWVALTFLDAVD -RGKLRLTDTTTITKNDLTLHQPSAAMVKTGGTSYSDLMRRAMTRSDNTANDTLLRAVGGP -EAVRGYLARRMIKDIRFGPGERLLQSNYLANPPDGAAPTAIVGALAKLKQGDLLSADSSR -LLLSVMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Limnoraphis robusta TaxID=1118279 RepID=UPI00066BC90B ---NLKQQILALTENSNLKPGVLLLDLDTGGYV-DINSESAFMAASTIKVPILVAFFQAVD -EGKIRLDETLTMQDQHIAGGSGDMQYKPAGTFTALETATKMIVVSDNTATNMLIERLGGA -EFINQKFLDWGMKNTVIRDVLPDLRGT------NKTTPRDLVNLLTQLNQGGLVSMKSRD -RIFRIMEKTEN-DSLLPSGLGKGAVIAHKTGNLKL-VTGDVGLIDLPNGKRYLLAVIVER -NEED-SAAESLIRNISKTVYEDf ->[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. An55 TaxID=1965646 RepID=A0A1Y3WD69_9BACT ---TVSHRIEQLLQDKSATVGVACSI--NGQNF-AFNDTVRYPLMSVFKLHVAVAVLQRME -ADGTRLDEILHIDSTQMRRYSPLLDRYPSGCISYAQLLHYALALSDNNACDLLIARAGGI -DAVKSCIDRAGITGYDLTETEASMHANIPACYRNWGHPSSVVQLLQKIHDGALLNEEHTR -FICSTLVEISTGTNKIRAGLPSDITLGHKTGSSGTIADNDAGFIVLPDGRVCYLTVFVKD -SRESDATNADLIAQITRIIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Hormoscilla sp. GUM202 TaxID=2480853 RepID=A0A533P1N3_9CYAN ---SLRQEVQTLAAANELIPGVFILDLDRGAYV-EVNSSSTFAAASTIKLPILVAFFQDVD -AGLLRLDEQLTLRREHVATGSGSMQYHQGTQYSALEAARMMITISDNTATNMLIEGLGGI -DVLNQRFKSWGLRTTVLRNPLPDLEGT------NTTNPRDLAYLMARINQGNLTSGRSRD -RMLEIMERTET-TPLLKPGLGEGATIAYKTGNIGS-MIADVGLISLPKGKRYIAAVMVNR -PFND-DRARELITQISRAAYR-- ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-2100 TaxID=1954172 RepID=A0A1Z4H4P4_9CYAN --kALEPQIKALMNRYSLQTGMFFLDLDTGNYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVRLDEKLTMRGDLVTNGSGEMQERVGKKYTALETITKMVTISDNTATNMIIDRLGGA -AKLNQRFRSWGLKDTVIRRLLADLRGT------NTTSSQDMARVLALLVNNKLVSLSSKE -QALDILRHTSI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVKR -PYKD-SRGRDFIRQVSQLVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fluminis TaxID=511487 RepID=A0A3M8DT06_9BACL ---SLQEKLEAVLSESSAVFGVTVKHIGTQEEA-RINADRYFQMASTFKVPILAALFRDVE -AGRLRLEDRIRLTEDDLVAGSGVLKEFLPGVVAIRDLAMLMIIVSDNVGTDKVVELV-GK -ERVEAFMRELGLNGISVKFDCWELLSFQPSPENNVATPSDMGRLLELIATGQLVSQEACD -GILDIMKRQQL-RNRIPYSLPDKTVIACKSGTIGS-VVNDVGIVYLPDKGAFTIAAMSQG -NG-TMKEGEQLIARLALTAYEHf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. CENA543 TaxID=1869241 RepID=A0A2I8A1Q4_9NOSO ---QLDTEIKRLMSRYSLAPGMFFLDMETGEYL-DINGEKIFPAASTIKFPILIALFQEID -AGRVSLNETVVMRRDLMTGGSGNMQYKPGTKFSLLETATRMMTISDNTATNMVIDRLGGK -NKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRVAALIANNKLLSSNSHD -KVMDIMVRCKN-RSLLPAGLGKGAVIAHKTGTLGR-VLGDAGIIETPSGKRYLAGIMVAR -PFGD-ARARSFINQVSRLVYG-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pyrinomonas methylaliphatogenes TaxID=454194 RepID=A0A0B6WUT6_9BACT ---DLRGQISALIRASGAKVAVAFHDLETEREL-LIDADESFHAASTMKVPVMMEVFRQAQ -AGRLALDERLKVKNESIADGSPYSYRRVGSEATVRELVRLMITESSNLATNLLIERV-TP -KSVMELVHNLGADGMRVLRGVEDGK-AYARGLNNTTTARALMILLKAIAEERAISPQASA -EMREILLAQKF-NEGIPAGLPPGVRVAHKTGSITR-IYHDAGIIYVPGRKPYVLVVLTRG -IA-DEGRAHQLVADISRAIYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Crocosphaera chwakensis CCY0110 TaxID=391612 RepID=A3IUA3_9CHRO ---ALKEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFQEVD -KGNMHLDQMLTMTKDVMVSGSGDMQYMQENKFPAIEVATKMIIISDNTATEMLVKQIGGK -EVLNQRFKEWGMKHTEIHNILPDLEGT------NKTSSEDLAKLLARIERGDLISTRSRD -RLIAIMEGTKT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-PAGRSLIQDISRTVYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_69_31 TaxID=1801944 RepID=A0A1G2WAU2_9CAUL ---ALQARLDELAAAYGEEVGIAVTDVTQGWTA-GVDHERPYPQQSVSKLWVAIAVMKAAD -EGRLDPYGWVTLTEEDRSVYQPVSYRIGAGGTPISDLLRRALVESDNAANDKLMRELGGP -EGVAATLEGMGLTGVKVGAYERDLQAAYLADPLDGAAPGEVTTALAALSRGELLSPQSTE -WLIGLMAQARTGPRRLKGGLPAGWTIAHKTGTGQSVGINDVGLITAPDGHVYAVAVMMRH -TRKPVPERLAFMQAITRAVAEQw ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. PP-CE-3A-406 TaxID=2135659 RepID=A0A3M0FNV5_9SPHN ----LVNAISELHSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTIGDLLTRALTHSDNTANDRLLARVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDILSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQRLIQQAAAAVAH-- ->[subseq from] Probable beta-lactamase n=1 Tax=Arthrospira platensis (strain NIES-39 / IAM M-135) TaxID=696747 RepID=D5A0K8_ARTPN --kDLKNQLESVAATSDVSPALMFLDLNTGGYV-GLREQSIVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALETATKMMTISDNTATNMIIDRLGGF -QVLNQRFRSWGLTDTMARNPLPDIEGT------NKTTPRDMVNLFSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVGNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAER -TNG-NQAAESMIQKMSRQVYEY- ->[subseq from] Beta-lactamase n=4 Tax=Sphingobium TaxID=165695 RepID=A0A081T4H2_9SPHN --------VRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDALLRAVGGP -DAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingobium francense TaxID=332057 RepID=A0A4Q4J9Z1_9SPHN --------VRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Alistipes sp. TaxID=1872444 RepID=A0A358RBJ6_9BACT --eQFERRIDRILEPCEATVGVAVLAPD-GTPI--TRNDRPLPMLSVFKFPVALAVLDRAV -REGISLSTPVAVGPEWLDSYSPMRDSLPPQGLPLGRLLAYAVSQSDNIACDRLIDFAGGP -GAVDGYLKRLGITEIRITATERTMHLATENQRINTARPSALCSLFDRFLQVELLPQRETA -WLRGLLEGCATGRNKLRAGLPPEVRLGHKTGSSDRTADNDAGYVVLPDGRHYCITVLVTD -SHHDDARNAGVIAAISEAAYEYf ->[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium BRH_c25 TaxID=1734399 RepID=A0A101W818_9FIRM ----FKKNLEEIINSSNANIGVAIKNMNTGETI-MINEGLAFRSASTIKLLIMSEILKEVK -EGEHTLDEPVVFADSIKVGGCGILKELNSGHFTIEEIITLMIILSDNTATNILIDMS-GM -DRINSMALELGLKNTELQRKMMDFEAA-KAGKENKTCAEDMMRILELIYNGENIDEKYSS -IMLDILKRQQI-VGRLDLYLPEDTVIAHKTGDLDK-LEHDVGIVFLPNCT-YIICVLTSE -NN-SNREGQEIIGKISQLVYNSy ->[subseq from] Uncharacterized protein n=1 Tax=Calothrix desertica PCC 7102 TaxID=232991 RepID=A0A433V414_9CYAN ---SLKSAIQNLAIQNNLTPGVFVTDLDNGGYV-DFNGGAMFSSASTIKLPILIAFFQDVD -EGKINLEETLRTSKSTVAGGSGDMQNRPGTQYGILEVATKMMTISDNTATNMLIERMGGI -EKLNERFRSWGLNTTLLGNILPDIEGT------NKTSPKELSNLMAMITKGNIVSSQSRE -RIIDIMQRTVK-DTLLPAGLGQGAKIAHKTGEIG-GILADTGLVELPSGKRYLISVMVQR -PRND-VSAEKLINGISRAAYQQf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chlorophenolicum L-1 TaxID=690566 RepID=F6ET74_SPHCR --------VRSLGQSFNGKVGIAVRRVGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=1 Tax=Parapedobacter indicus TaxID=1477437 RepID=A0A1I3CNX1_9SPHI ---TLRKDIERILANYQARIGIAVHNQDFSDSL-IVAGNYHFPFQSVYKFHLGIAVLNQVD -NGILKLDQPIRVSKAAVTTYSPIKDKYPDGVLPLSEVIKYTIAESDNVGCDILFELLGGP -DAVQAYFSDKGYGNLSIKLTEAVQQKEWDLQFANWTTVGSCNHILYDYYTKRLLSPTSHQ -FLWDTMRGTKTGVNRIKGDLPTGTVVAHKTGYSGTAAVNDIGVVSLPNGDVFYMTVLVTD -SKEEESVSAKAIAEVSKAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fluminis TaxID=511487 RepID=A0A3M8DI39_9BACL ---ELQEKLERIAREMPGTFGVAIKHLETGEEA-SLFGDELFQLASVFKIPILATLFRDVE -EGRLSLGERVKLQADERVPGSGVLQELDPGAVTIKDLAMLMIIVSDNYGTDQVLKHV-GI -ERVNRFMNELGLVKTNIQHDCWRLLTLEPRPENNVSTPQEINRLLEMIAKKQLISEAACD -GMLNILKRQQF-TSRIPNLLPGQARAAHKTGTIGS-CVNDAGIVYMPQGKGAFAITVLSR -DNESTNQGAQTIARLSRAAYDHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH9-F2 TaxID=1768778 RepID=UPI00082EF4BF ---ALQGRVSELIRAFPGKAGAVIRSVDEGWVV-GQGGDLSLPQQSVSKLWVAMTVLAQRD -AGRLKLDEPVLVTRDDLTLHQPIAALVKGEGTTLSGLLTRALTQSDNTANDRLLTYVGGP -AAVRRFLASKELTGIRFGPGERLLQSRYIDNPPDGASPNGITAALARLARGELLTETSTR -ILLDTMAASRTGHARLRAATPAGWQLAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TTAPMRDRQKLIQDVCAAL---- ->[subseq from] serine hydrolase n=1 Tax=Planktothrix tepida TaxID=1678309 RepID=UPI0009340622 ---DLKTAILALAQDSKLKPGVFLVDLDTGNYV-DISGETPIPAASTIKVPILVSFFQAVD -EGRIRLDEILTMEEKHIAKGSGELQKPVGSKFTALETATLMITNSDNTATNMIIDRLGGI -ESLNQQFVSWQLKQTQMQNILPDLEGT------NKTSSKDLVTLMAEINQGKLVSVKSRD -FMLRIMQQTRN-RSLLPSGLGEGAFIAHKTGNIDT-VSGDIGLVDMPNGKRYLVGVLVQR -EA-DDPQAEELIRQISSTIYQYf ->[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Planktothrix tepida PCC 9214 TaxID=671072 RepID=A0A1J1LNE4_9CYAN ---DLKTAILALAQDSKLKPGVFLVDLDTGNYV-DISGETPIPAASTIKVPILVSFFQAVD -EGRIRLDEILTMEEKHIAKGSGELQKPVGSKFTALETATLMITNSDNTATNMIIDRLGGI -ESLNQQFVSWQLKQTQMQNILPDLEGT------NKTSSKDLVTLMAEINQGKLVSVKSRD -FMLRIMQQTRN-RSLLPSGLGEGAFIAHKTGNIDT-VSGDIGLVDMPNGKRYLVGVLVQR -EA-DDPQAEELIRQISSTIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Planktothrix sp. UBA10369 TaxID=2055760 RepID=A0A354WIV5_9CYAN ---DLKTAIMGLAKDSKLKPGVFLVDLDTGNYV-DIQGEEALPAASTIKVPILVSFFQAVD -EGRLRLDEVLTMAEKHIAKGSGELQDQPGSKFTALETVTLMIENSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMAEINQGKLISLKSRD -LMLRIMEQTRN-RSLLPSGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYLVGVLVQR -EAN-DPQAPELIRQISSTIYQYf ->[subseq from] Beta-lactamase n=1 Tax=Limnoraphis robusta CS-951 TaxID=1637645 RepID=A0A0F5YMC3_9CYAN ---NLKQQILALTENSNLKPGVLLLDLDTGGYV-DINSESAFMAASTIKVPILVAFFQAVD -EGKIRLDETLTMQDQHIAGGSGDMQYKPAGTFTALETATKMIVVSDNTATNMLIERLGGA -EFINQKFLDWGMKNTVIRDVLPDLRGT------NKTTPRDLVNLLTQLNQGGLVSMKSRD -RIFRIMEKTEN-DSLLPSGLGKGAVIAHKTGNLKL-VTGDVGLIDLPNGKRYLLAVIVER -NEED-SAAESLIRNISKTVYEDf ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. IPPAS B-1204 TaxID=2483801 RepID=A0A3M9ZEU8_9CYAN ------------------VPGVYVMDIDNGDFF-SFNGNATFSAASMIKLPVLIAFFQDVD -AGKIKLDEMLQIQQTDVAEGSGDMQYGVGTQYSALETATNMIVSSDNTATNMVIRRLGGI -QALNQRFRQWGLQQTLLRKPLPDLEGT------NTTSPKELASLMALLNDGKLISMKSRD -RAFEIMRRTAN-DSLLPSVMSPGSAIAHKTGDIGS-MLGDIGLVDLPSGRRYAIATMVKR -PHND-ARAQDLIRQIAAIVYEHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. 3P27F8 TaxID=2502213 RepID=UPI0010F91BF2 ---ELVARVDALVRSFPGIAGVAIRAVDEGWTV-ESGGRRRMPQQSVSKLWVAMTVLDQRD -SGRLRLDDPVTIYPADLTLHQPIASLVKPGGTTVSALLTRALTQSDNTANDRLLTLVGGP -AAVRSFIERKQLGDIRFGPGERLLQSAYITDPPDGAAPLAIADALSRLARGELLSETSTR -FLLATMGSTVTGRARLKAALPPGWSLQHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TMRPMRDRQQLIQAAAGAL---- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium ummariense RL-3 TaxID=1346791 RepID=T0K1S1_9SPHN ------SVVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNQLFPQQSVSKLWVSMAFLDAVD -RGKLRLADTTTITKKDLTLHQPTAALVGNTGTTYADLMKRAMTQSDNTANDTLLRAVGGP -DVVRGFLARRLIKDIRFGPGERLLQANYLANPPDGAAPSSIVAALAKLKEGDMLSAGSSR -LLLSLMEEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. YL-JM2C TaxID=1336744 RepID=UPI0004A8002B ---ALDAAIDRLGRRFPGDVGLAVRDVQTGWTS-HRRGLDYFPQQSVSKLWVSLTALDQVD -GGRLDLSRALTVTAKDLTLHQPIRALALRPGTTGDDLMVRALTQSDNSANDRLLHQVGGP -DAVRATLRGKAIAGIRFGPGEPRLQAEYLADPIDGATPIAMVDTLARLRRGDLLSPASTA -KMTAIMEETRTGALRLKAGLKPGWRLAHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TGRPLAERMKLMQSVVAATI--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W5B7T0_9SPHN ------------------------------------------------------------- ----------------------------------AAKVMELMIVRSDNRATDQLLAALGGP -VAIQQWLSSQKIPGIRMDRTIAQLLRGHLADSKDVATPVAMVTLLNTLDNGTVLTAQSRA -FLLELMSRCATGTRRIRALLPVGTRVEDKTGTLD-GITNDVGFITMPDGRRVAVAIFARG -GR----DRQPVIAEVARVIYDRf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WMB9_9BACT ---DLQNKIETIISSTKADIGVAVMVPSSHDTI-LVNGMKPYTMMSVVKFPQAVYILSLVD -RGKLRLSQKVNFDAAELQRHSPMRDKYGKDPVTLEETIMWAVSHSDNIACDRLFELGGGV -AANEKYFQDLGYHDFAIGVDYKHLDEK--TMRANNTSPLTMTRILERFYNGKLLAGSSRN -LLLKFMTQSQNPEDRIKGNLPKGTVVAHKTGTSANGVFNDVGIITLPSGKQIILSVFVSA -SKEKSDDNAKAIAAIAKAVFDHy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15C TaxID=2714944 RepID=UPI00140B1F86 ------------------------------------------------------------- ---------------------------------SARSLMRRMLIHSDNGATDVLIRDLGGP -QALDSWLKDNGVQGLRVDRTIAQLLRDKRWDRRDSSTPTAMVDLLRRIYKAELITPKSRN -YLLDVMGQCQTGKNRIKGLLP-GVPVEHKTGTLN-GYSSDVGFITMPDGRRVAVAFFARG -GD----DRPRTIAQAARAIYDGf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. HDIP04 TaxID=428994 RepID=T0HGJ1_9SPHN --------VRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudanabaena sp. ABRG5-3 TaxID=685565 RepID=A0A2Z5WTQ1_9CYAN ----LVSKIKELAKEKDLSMQMMMVDLDSGAYV-QIGANQVIAAASTIKTPLLVAFFQDVD -AGKIKLDEQLEITDDVKVGEAGDFQFLPTGTISALETATQMIIISDNTATNMIIKRLGGN -AAVNQRFKSWGLNNVVVNNKLPDLEGT------NTISTQDMVTLLAMLDKGKLLEPRSRD -RFMDIMRRPVT-NTLLPKGIGEEARIIHKTGDIRS-AVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRATYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Caulobacterales bacterium 32-69-10 TaxID=1970503 RepID=A0A258FMK1_9PROT ----LTLRLEQLRKDFGGSVGIAVHDLQAGWTT-GSNGLAVLPQQSVSKLWVAIALLDAVD -RGEIDLAESVTVTPADLSVNQPIREKLAGGATTLGDLLAMQVALSDNAANDIVMRRVGGS -EAVQRTIAAKRLGAIRAGPEEKVLQPAYLADPDDGATPVALVEALARLKRGELLSPASTA -RLQQVMAQTSTGPMRLPAGLPMGWTISHKTGTGQSTGYNDVGLLGAPDGRTYAVAVMIGS -TTRPVPERMTLMATVAAAVVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-1A-559 TaxID=2135657 RepID=A0A4R2SV29_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERRLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGHRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WL07_9BACT ---QLTERLKAITSSAGGVVGLAVTHIESGRTV-NIQGTLPLPLYSVFKLPLAVAVLKDVE -ENRLRLDRKVLTTPAEIVPGSQENTDLWRKPRTVTELLELSVMRSDNTSADKLLQLVGGA -SAVTERMRSLGYQNLLIHSSVREYVAD--RKKVNTGTASDLTRLLVDLHQGRILQPPQLS -VLLGFMQRATTGQRRLRDLLPAGTQVADKTGSGAAGATNDVGLITLPKGGHLAIAVLVSD -AKLPTEEQEKLIAEVARVSYDA- ->[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. SR411 TaxID=1980935 RepID=A0A256BFL5_9CYAN --------VKELAKEKDLAMQMMVVDLDSGAYV-QVGANQPIAAASTIKTPILVAFFQDVD -AGKIKLDEQLEMTADVKVGEAGDFQFLPTGTITALETATQMIVISDNTATNMIIKRLGGF -TALNQRFKSWGLNNIVIKNQLPDLEGT------NTISTQDMVTLLAMLDKGKLIEPRSRD -RFMDIMRRPVT-NTLLPKGLGEEARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRTTYEYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3WH31_BRECH ---DLQKKIEELVGQATATFGIVIKHLETNEEV-KINEGHLFQMASCYKVPILATLFREVE -AGTIDLNTRVRLSLTDRVPGSGVLKEFDPGSVSLKDLATLMIIVSDNVGTDKILELV-GV -NHTDQYMKSIGLQDTYVNLTCWQLLSFTKSIENNVSTPADMALLLEKIARKELISKKACE -QMIDIMKRQHF-RDRIPNLLPAGTPVACKSGSVG-GVHNDIGIIYLPEEKGTVIVSAFSE -NNSSQLEAAQMIAKVAQSAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Phyllobacterium sp. OV277 TaxID=1882772 RepID=A0A1H0EPY3_9RHIZ ---ALQQRLEKLATGKDARIGICALD-QAGTSV-CVRGDERFSLQSVVKLIAGAATLDAAD -HGAVNIEDPIIIRSENLSLKQPLAKIVERNGTNAADLVRRAIVDSDSAAVDILIDRLGGT -GTINSFLAGKAISGIRIDRDERHLQTAYQKDPRDTATPRAMTEFLAALMNGKLISTGSTN -RLLAIMNETSTFPDRLRAGVGKDWSVAHKTGTSPNVATNDVGILTAPDGGKVAISVFVAD -SRETPTLRAMIIASAAQAVTEAy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1AW47_KLEPN ------------------------------------------------------------- ------------------------SEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIY--- ------------------------ ->[subseq from] Penicillin-binding protein, transpeptidase n=2 Tax=Geitlerinema sp. PCC 7407 TaxID=1173025 RepID=K9S5U5_9CYAN ----LKAEIQTIASQNQLSPAVLVVDLDSDAHV-DINAAVPLPAASTIKIPILVAFFQDVD -AGKIRLDEQLTMRQELVASGSGEMQYQPPGTFTALETATKMITVSDNTATNMLIERLGGM -ASLNQRFQAWGLPATALRNPLPDLEGT------NTTSPHDLVQVMALVNRGDLMSQRSRD -RLLSIMHDTVN-DSLLPQGLGEGAIIAHKTGDIGS-LLADAGLVDMPSGKRYLIAVMVKR -PH-NADAAYELIQQISKATYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. YZ-8 TaxID=2319844 RepID=A0A494THN8_9SPHN ---RISAKIAELGRAFGPGVGISVRDIREGWST-SWNGDRLCPQQSVSKLWVALAVFDAMD -RGALRPDDAMIVTRNDLTLHQPIRALVGEQGATVSELLERQMTQSDNTANDMLLRRIGGP -TAIRSMLTRLRISNVRFGPGERLLQSAYAENPVDGAAPNAITLALARLVRGDLLTPTGTQ -NLLALMERSKTGRARMKAAIEPDWLLAHKTGTGQVAGFNDVGLLTAPDGHIYAVAVMVAR -SSRPIAERQAIIANVARAVIDDw ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. EhN03 TaxID=1849358 RepID=UPI00128FF08F --rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRSADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTPPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9Q4A1_9BACT --qKLEASITDVDRSLDGVMGVAIEDLNSGQKY-LLRGDDVFPQASSIKIAVLAELYRQAQ -QGKLKPTDVYTVKASDLVADSPIMNGLTPGVVTLRDLATMVVAVSDNSAANILIDRV-GI -ESVNSLLDSLGLAHTRLRRKMMDLKAA-SEGRENISTPSEMMTLLEDVYRGKVLNKPLSE -DFFRLLSTKKN--SWIPRELPEDLKVADKEGELE-GVRNDSGIVFLENS-PYILCVMTTY -LRR-ERDGEEAISKISVDAYRMf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9QDY2_9BACT --qKLEASITDVDRSLDGVMGVAIEDLNSGQKY-LLRGDDVFPQASSIKIAVLAELYRQAQ -QGKLKPTDVYTVKASDLVADSPIMNGLTPGVVTLRDLATMVVAVSDNSAANILIDRV-GI -ESVNSLLDSLGLAHTRLRRKMMDLKAA-SEGRENISTPSEMMTLLEDVYRGKVLNKPLSE -DFFRLLSTKKN--SWIPRELPEDLKVADKEGELE-GVRNDSGIVFLENS-PYILCVMTTY -LRR-ERDGEEAISKISVDAYRMf ->[subseq from] serine hydrolase n=4 Tax=Sphingomonas TaxID=13687 RepID=UPI0008336EF6 -----VTGIDAIATEFGGKVGIAVKSIDEGWMV-AKNGDQRMPQQSVSKLWVAMTMLDARD -KGRVRLEDSVTITRNDLTLHQPIAGLMKDGSTTVGELFRRAMTMSDNTANDRLLQLVGGP -QAVRGFIADRNLGNIRFGPGERLLQSSYVAEPIDGAGAAAIANALARLKRGELLSAGSTT -LLISTMQESRTGRARLKGAVPAGWVLGHKTGTGQTAGFNDVGILTAPDGKSYAIAVLIGD -TRRPIPERQQLMQTVVASVVA-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter pelagi TaxID=994320 RepID=UPI001323A67D ---RFEQELEEIAASLEGTVGIAVTDVETGRSY-AIRGDDWFPQQSVSKLWVALTALDEVD -QGRLELDEGVVIGPKDLTLHQPIRDLVRARGTDYADLIQRAITHSDNTANDRILRRVGGA -EAVEDFFAAKKITGVRFGADERSKQSGYLADPVDGAMPLGITRALARLARGELLSPASTA -LILATLNATRSGPQRLKGGVPPGWSIGHKTGTGQQSGYNDIGILTSPDGHRYALAVMIGR -TREPTLERMRMMQAVTVAT---- ->[subseq from] Beta-lactamase class A n=1 Tax=Cylindrospermum stagnale PCC 7417 TaxID=56107 RepID=K9X017_9NOST --kALEPQIKALMSRYSLQTGMFFLDLDNGDYL-DIGGDRVFPAASTIKLPILLAFFQSLD -EGKVSLDKQLTMRGDLVASGSGVMQERVGKKYTALETITKMSVISDNTATNMIIDYLGGP -ARLNQRFRSWGMKDTVIRRLLGDFRGT------NTTSPQDLARALALLVNDKLVSSQSKE -QALDILRQTKT-RTLLPAGLGKGAVIAHKTGDIGF-LIGNAGFITTPNGKHYLAAIFVKR -PYKD-VRGRDFIRQVSQLVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Phormidesmis priestleyi ULC007 TaxID=1920490 RepID=A0A2T1D5T2_9CYAN -----KNNLQALVQQTQLSPGMMIVDLDTNAYL-NINASVALPCASTIKLPILVAFFQDVD -AGKIRLDEMLTMRSDLIATESGEMQQPVGSQFSALETATKMITVSDNTATNLLIDRLGGK -EALTQRFQSWGLTSTAIQNRLPDVEGT------NTSSSQDLVTLLGLVSNGKLLSMRSRD -RMLDLMRHTVN-NSLLPSGLGEGATISHKTGSIGS-MIGDVGLIDMPSGKRYLIAAMVKR -PRND-ERAEELIRQVSRLTYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf34 TaxID=1736216 RepID=A0A0Q4L9K9_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGP -SAVRGMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQKLIQNAAAAVANY- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI0013DEA125 ------------------RVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNVGDHVTRLDRWEPELNEAIPNDERDTTMPVA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium ST_bin14 TaxID=1978762 RepID=A0A1W9JVW9_9PROT ---QLVSTINALRAQFSGSVGIAVRSIDKGWTV-ASNGDAKLPQQSVSKLWVAMAVLDFRD -SGRLTLDDAVTVTREDLTLHQPIAMMVKGDGATVGELLQRALTTSDNTANDRLLRFIGGP -DTVRAFIQRKGLGSISFGPGERLLQSSYIANPPDGAAASAIAGALAMLKKGELLSAQSTS -YLIATMESSRTGKQRLSGAVPAGWHFGHKTGTGQTAGYNDVGILTAPDGQSYALAVMIGD -TPRPVPERQALMQSVVASVVAY- ->[subseq from] serine hydrolase n=1 Tax=Oxynema sp. AP17 TaxID=2064643 RepID=UPI001442E45C ---ALKTELQGLAAPHDLTPGIFVVDLDTGGYV-DLNGSSSFSAASTIKLPILIAFFQAVD -EGKVRLDQMLTMQAEQVAGGSGMRYSAPGTEYSALETATKMITISDNTATNMLIDLLGGA -EILNEQFRGWGLSSTQISNPLPDLEGT------NTTSPRDLVQLMSMVEQGGLVSLRSRD -RLLDILTATVN-DSLLPQGLGQDAAIAHKTGDIGT-SIADAGLVDRPDGKRYLIATLVKR -PHND-PQGEELIRQMSKAVYDSf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KJR1_9BACT --------FQELEEKYDATLGIYALDTETNKEI-SYNADERFAYCSTYKALAAGAILEKYS ---IEELDNVIYFEEEDVLSYAPVAKDKVDTGMTIREICDAAVRQSDNTAGNLQFALLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLAFNLKEYVTGDILSDDKKE -IFIDWMSNNATGDELIRAGV---------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium J007 TaxID=2420339 RepID=A0A3M2GPK8_9CYAN ---ALKTELQGLAAPHDLTPGIFVVDLDTGGYV-DLNGSSSFSAASTIKLPILIAFFQAVD -EGKVRLDQMLTMQAEQVAGGSGMRYSAPGTEYSALETATKMITISDNTATNMLIDLLGGA -EILNEQFRGWGLSSTQISNPLPDLEGT------NTTSPRDLVQLMSMVEQGGLVSLRSRD -RLLDILTATVN-DSLLPQGLGQDAAIAHKTGDIGT-SIADAGLVDRPDGKRYLIATLVKR -PHND-PQGEELIRQMSKAVYDSf ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium zucineum TaxID=284016 RepID=A0A2W5PEB6_9CAUL --eALQSRLDELAAAYGEEVGIAVTDVTAGWTA-GVDQDRPYPQQSVSKLWVAIAIMKAVD -EGRLDVESPVLLSEADRSVFQPVSYKIGANGTAMSDLLRRALVESDNAANDRLMRELGGP -EGVADTLHGMGLSSVKVGAYERDLQAAYLAEPLDGAAPAAITAALAALSRGELLAPASTQ -RLIGLMAEARTGPRRLKGGLPPGWSIAHKTGTGQSVGINDVGLLTAPDGRTYAVAVMMRH -TRHSVPERLAFMQSVTRAVAEQw ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E3MWZ1_9PLAN -----SQKLSSLLQDHEGNVSVAIKHLSTGERF-EFHANRTMPTASLIKIAVMVEAYRQAD -AGRIDMDQRITLLAGDKVPGSGILTTHFSAGLSLRDAIRLMISHSDNTATNLVLDQI-GI -RSTAETMEKLGFPNTKIHAKVFRRETRSKQFGLGSTTALETAHLLEQLYRRQLASPAASL -AMLKHLENCQD-RTKLPRFLDSHTKIAHKAGSLSR-VRTDAGIIFLSSG-PLVICVLTSD -NKTDENASEILCARVAKVACAHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G7N3_9SPHN ---QLDAAIVALHQGFEGKSGIAIRAVDDGWTV-EVGGRQHLPQQSVSKLWVAITLLDLRD -QGKARLEDPVVVRPEDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERQLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQSVAAAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=[Leptolyngbya] sp. JSC-1 TaxID=1487953 RepID=UPI00068C1ABC -----------------LVPGVYVMDIDNGNFF-SFNGNATFSAASMIKLPVLIAFFQDVD -AGKIKLDEMLQIQQTDVAEGSGDMQYGVGTQYSALETATNMIVSSDNTATNMVIRRLGGI -QALNQRFRQWGLQQTLLRKPLPDLEGT------NTTSPKELASLMALLNDGKLISMKSRD -RAFEIMRRTAN-DSLLPSVMSPGSAIAHKTGDIGS-MLGDIGLVDLPSGRRYAIATMVKR -PHND-ARAQDLIRQIAAIVYEHf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 43529 TaxID=1840705 RepID=A0A367QMZ8_9NOSO ---ELKTPINKLVSRYKLTPGMFFMDLETGDYI-SINGNKAFPAASTIKYPILIALFQEVD -AGRIKLDETLVMQRKHVVGGSGSMQKRVGSKFSVLKTATMMMTISDNTATNMIIARLGGI -PKLNQRFRSWGLQNTALRRMLGDFNGT------NKTSAKDLVRLSALMVNNQLLSDKSES -QVLGIMYGCQN-RRLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTSSGKRYLAGILVKR -PNHD-KRARDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase class A n=1 Tax=Propionispora hippei DSM 15287 TaxID=1123003 RepID=A0A1M6BVY0_9FIRM --kQLEQTIQQILTTCPCQQALLVRHLPSGRQF-ALNPDQVFPAASMIKLPIMYEVMRQAS -QGLLALEELLEVTEAVRVGGAGILQERPGIALTVQELVTLMIVISDNTATNLLLNRL-GL -AAVNNTAEQLGLTNTVLRRRMMDFAAA-RAGQENHTSAADIAKLLEIMYQQTTLPPEYGK -LMLNILKRQQI-RDKLPFYLPEDIAIAHKTGTLD-GVEHDAGILFSAGG-PYLISVMTAG -LPAN-YQGLQLVAQIGRAIFEY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 66-10 TaxID=1895848 RepID=A0A1M2ZEY2_9SPHN ---ALAERIETLVRGFPGVAGIAIRAVDEGWTV-EYGARRLMPQQSVSKLWVAMTVLDQRD -SGRLRLDDPVTLYPADLTLHQPIAALVKPSGTTVSSLLVRALTQSDNTANDRLLKLVGGP -AAVRAFIERKQLGDIRFGPGERLLQAAYIADPPDGAAPLAIADALARLARGELLSETSTR -FMLTTMGSTVTGRARLKAALPPGWTLQHKTGTGQNAGFNDVGLLTAPDGRRYAIAAMIGD -TTRPMRDRQLLIQAAASALT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI10_KLEPN ------------------------------------------------------------- -------------------------------GMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELVTLASRQ -LLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGMIAALGPDGKPSRIVVINTTG -SQATMDERNR------------- ->[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=1 Tax=Pirellula staleyi (strain ATCC 27377 / DSM 6068 / ICPB 4128) TaxID=530564 RepID=D2QYA8_PIRSD --eKLAKRLEPIIAAHQGQVAVAIKHLPSEATF-EYRAADPMPTASLIKLPVMIEAYRQSA -AGKLDLAQSITLTEKDKVPGSGVLTKHFSAGLTLRDAIRLMMAFSDNTATNMVLERT-GI -PAVNQTMEKLDLVETKIHSQVSVLPERSKQFGLGSTTAAETVALIEKLHQGKLATPAICA -EMLQHLYATEE-ESCLPRLLPEGVRVAQKTGAVS-AVRTAAGIIESNAG-PILICVLTSE -NRTSDNSAELLIANIARETHEHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TCM1 TaxID=453246 RepID=A0A196M8N7_9SPHN ------NVVRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTITRNDLTLHQPSAAMLKNGSTSYSDLMRRAMTQSDNTANDALLRAAGGP -EAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSSASSR -LLMTIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVSRAVAA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=A0A1H7RH27_9SPHN ----LRAEVDRLIGEFPGKAGAAIRAVDDGWTV-QRGGALSLPQQSVSKLWVAMTVLSQRD -AGKLRLDDPVLVTTNDLTLHQPIASLVRGEGTTVMGLLTRALTQSDNTANDRLLRLVGGP -SAVRAFIAEHQLGAIRFGPGERLLQSRYIDNPPDGAAPLAIADALARLARGDLLSETSTR -VMLDTMGASVTGRARLRAALPSGWTIAHKTGTGQNAGFNDVGLLTAPDGKRYAVAVMIGD -TRAPMRVRQQLIQNVAAAL---- ->[subseq from] HGE-1 beta-lactamase n=1 Tax=Azospirillum sp. CAG:239 TaxID=1262705 RepID=R6J3X4_9PROT --nSLESRLRRIIRLSNTDAGVAVVSGSRNWAV----GNRKRPLLSVFKFFIAVQTLRQME -QTETALNAKLTVKENMTDAYSPMLKKHPRRPISLAELLEYMIAESDNNAADILLEYSGGT -GQLEKFLHDLGFSGIDIRVNEKQMNQKAENQYLNQAAPSDVAGLIKLVFEKDVLSAEHRK -FLADIMIKTSTGADKIKLGLPPGVIFGHKTGSSSRTADNDAGFVTLTNGSTYYIAVMITE -SKHDDRANAALAAQISQTVYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Crocosphaera subtropica (strain ATCC 51142 / BH68) TaxID=43989 RepID=B1WW03_CROS5 ---ALKEKIQKIDAKYNVKPQAWFMDLDNGAYV-TYNGTQPVPAASTIKIPVLVAFFQEVD -KGNMHLDQMLTMTKDVMVSGSGDMQYQVDKKFPAIEVATKMIVISDNTATEMLIKQIGGK -EVLNQRFKEWGMKHTEIHNILPDLEGT------NKTSSEDLSKLLARIERGDLISTRSRD -RLIAIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-PAGRSLIQDISRTVYQHf ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium sp. NYYP31 TaxID=2546448 RepID=UPI0012E10940 ---NLESKINAILSNYDAKVGVAINNNDFSESI-LINSEHPFPLQSTYKFHLGIVILDQVD -QGKLTLDQPISISKKSVTTYSPIKDKYPNGTLPLHEVLRYTIAESDNVGCDILFELLGGP -DFVQKYFDDQGYQDLSIKLIEEIQQANWDLQFDNWTKVKTSNKILFDYYKKQQLSEASYK -FLWDTMRSTSTGRNRIKGLLPQGTVVAHKTGYSGVNAVNDIGVVSLPNGEVFYISVYVTD -SKETEPRSAEIIAKVSKAAYDYf ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter lutipelagi TaxID=1964208 RepID=UPI0010FA4F94 --qALDRRLSELGGTFDGQVGIAVVDIAQDASV-HYNGLQQLPQQSVTKLWVALTALDMVD -QGELDLSETVAIMRDDLTLHQPLRAQVLKQGTDFGDLLQRAIITSDNTANDRLLQRVGGP -DAVQAFLDDHELGSIRFGSDERTKQSAYLADPEDGASAVAIAQALASLSRGELLSDRSTQ -ELLGILSRTRSGPRRLKGAVPPDWAIAHKTGTGQQSGYNDIGLITSPEGKTYAVAVLIGR -TRAPNPRRMELMQRVVHAVLEY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf33 TaxID=1736215 RepID=UPI0009E743C4 ----LTRAVETLRDNFDGLAGIAIRSVDDGWAVdSVDADRRMPQQSVSKLWVAMTVMDQID -SGRLTLDTPVTIRREDLTLHQPVASLVAKDGTNVRDLLKRAMTQSDNTANDSLLRTVGGP -AAVRSFISRKGLGNIRFGPGERLLQSRYVADPVDGAAPAAIASALARLKKGVLLSPASTR -YLVETMESSKTGKYRMRGAVPPGWTFGHKTGTGQTAGYNDVGLLIAPDGRTYAVAIMIGD -TRRPIQDRQLLMQGVVSAIVA-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium herbicidovorans TaxID=76947 RepID=A0A086PB28_SPHHM -------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTVLDAVD -RGKFRLSDTTTITRKDLTLHQPSAGLVGSSGTSYSDLMRRAMMNSDNTANDTLLRSVGGP -EAVRSYLARRFIKDVRFGPGERLLQANYLASPPDGAAPSAIVHALAKLKEGDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPAGWRYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTEPIPARWELMQAVAKAVAA-- ->[subseq from] Uncharacterized protein n=1 Tax=Brevundimonas sp. Root1423 TaxID=1736462 RepID=A0A0Q7SCJ4_9CAUL -----------------------------------VNGDRPSSMQSVMKLLVGLAVLDAVE -RGELGLEDRVTLTRADVSVVQPIESRLGPSGTTIGELVRGAVIQSDSMATDWLIARLGGP -GAVQAFLERKGVTGIRLDRDERHLQTAYQQDVRDTATPRAMATLLYRLASGDLLGTSSTR -WMLATMKETQTFPDRLRAGTAPGWDAAHKTGTSNTGATNDVGVLTSPLGEPSGVAVFLAN -SPAEAPARAAAIAKVARIVTR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9S0Q3_9BACT ---RLGAVITDVDRDLDGVLGVAIEDLTSGQRF-LLRGNEVFPQASSIKIAVLAELYRQAQ -SGKLKLNDLYTVQASDLVPDSSIMGGLTPGIVTLRDLATMMVAVSDNSATNVLIDRV-GM -ENVNGLMNSLGLANTRLRRKMMDLKAAG-EGRENISTPQDMMVLLEGLFRGKVLSKEMTD -DFFKMLSTPKS--SFIPRDLPEGLKIANKPGELE-GVRNDSGVVFLANR-PYIICVMTTY -LRR-ERDGEEAIGKISVAAYRMf ->[subseq from] Beta-lactamase n=1 Tax=Acaryochloris sp. RCC1774 TaxID=1764569 RepID=A0A2W1JBJ9_9CYAN ------------AAQKGLTPGMYFLNADTGATL-DIAGDQAFSAASTIKVPVLLAFFQAID -AGEVNLDDKLVMRPDLIATESGTMQYQPPGTFSALETAQKMITISDNTATNMLIDLLGGA -DRLNRQFRGWGLKHTEIRNPLPDLDGT------NTISPQDLSNLMLKLSRGELLSIESRD -QTLKIMRNTVT-KTLLPRGLDSAASIAHKTGDIGS-IVGDTGLIEMPNGQRYVATVMVER -PHND-PRAQELIRKISRMTYKVf ->[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI000707FC99 -hkKTFEKIKFIADTSNGVIGVAVKNLETGETF-FINENLIFPQGSAIKIPILIEVIKQAS -EGKFKLTDKIKIEKKHQVGGSGVLKEFGDGTLSIYDLAVLMITVSDNTATNILIDLV-GM -ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPLEAMKLMEMLYKGEVISKEISN -QVIDILKKRKE--ANLNKYLPEDIQIANKPGGIE-GVTCEWGIVYLPRH-PYVIVVMSNY -NL---KSANETIAQISKIIYEHf ->[subseq from] serine hydrolase n=1 Tax=Cronobacter dublinensis TaxID=413497 RepID=UPI001319D963 ------------------------------------------------------------- ------------------------------------------ITMSDNTAANLLLTPIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium chlorophenolicum TaxID=46429 RepID=A0A081RD19_SPHCR --------VRSLGQSFNGKVGIAVRRIGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPTAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSQ -LLMSIMSEAKTGPQRIKGGVPTGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Class A beta-lactamase n=2 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=A0A2L2NVM3_9NOSO --kALEPQIKVLMSRYSLKTGMFFLDLDTGDYL-DIGGDRVFPAASTIKLPILIAFFQDLD -AGKVTLQENLTMRRDLVTNGSGSMQERVGKKYTALETITKMITISDNTATNMIIDRLGGA -ARLNQRFRSWGLKDTVIRHLLADLRGT------NTTSSQDMARVLALVVNNKLVSLQSRE -QALDILRHTTI-HTLLPAGLGKGAVIANKTGDIGF-LIGDAGFVTMPNGKRYLAAIFVTR -PYKD-TRGRDFIRQVSQLVYNY- ->[subseq from] Putative beta-lactamase n=1 Tax=Cyanothece sp. (strain PCC 7425 / ATCC 29141) TaxID=395961 RepID=B8HLP2_CYAP4 -----EQQMNEIAARPGLTAGAFFLNLDTGAYA-DVNGAATFPAASTIKTPILVAFFQDVD -AGKIKLDERLVMRPDLIASEAGIMQYKPGTKFSALETADLMITISDNTATNMLIDRLGGA -AALNQRFLSWGLQQTVIRNWLPDLKGT------NTTSAKDLAYLMMLVGRGDLVSVRSRD -RLLDIMHRTVT-NTLLPQGLGEGAKIAHKTGDIGI-VIGDGGMVDMPSGQRYVAAAMVRR -PYND-VRGRELIQQMSRLTYQAf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacC n=1 Tax=Planctomycetes bacterium Q31a TaxID=2527968 RepID=A0A518GCE6_9BACT --sDLAAALQPLVDAHAGDVAVAAADLKTRISW-NYQGDQVMPTASLIKLPVMIEAYRQAQ -AGGLSLEHLIVLREEDKVPGSGILTEQFSAGLPLNDAIRLMMRYSDNTATNLVLDSI-GL -ESTAKTMAELGFPETRIHSKVFRRDTSIDSDRSGSTTANETVTLLSQLVRGELADESSTQ -SMLDHLFACEA-TNGFPRDLPAGTRVAHKTGSVTL-ARTEAGIIDSPAGK-IVLCVLTNN -NESENNAGNVLCAKLAKAAFD-- ->[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia NIES-25 TaxID=1091006 RepID=A0A1Z4L226_NOSLI ---ELKTPINKLVSRYKLTPGIFFMDLETGDYI-SVNGTKAFPAASTIKYPILIALFQEVD -AGRIKLDETLVMQRKYVVGGSGSMQKRVGSKYSVLKTATMMMTISDNTATNMIIARLGGI -PKLNQRFRSWGLQSTALRRMLGDFNGT------NKTSAKDLVKLSALMVNNQLLSDKSKS -QVLGIMYGCHN-RKLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTPSGKRYLAGIFVKR -PNND-LRARDFIRQVSQVVYGYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas edaphi TaxID=2315689 RepID=A0A418Q3M7_9SPHN ---SLAAQINAIGRGFNGIVGVSVVSLRDNWQA-DYNATRLFPQQSCSKLWVAVAAMDAVD -KGRVSLNDKVTLGRSDLTLHQPIRSKVLGGGTTLGSLLFTAITQSDNTANDKLMRSIGGP -EAVRNMIEAKNLGSIRFYDGERALQSRYIRDPYDGAAPRAVAEGLARLQKGELLSPGSTR -RLLSIMASTKTGGLRVRAALKPGWEWSHKTGTGQIGGINDIGILTAPDGTAYAMAIMTIP -NK-SDGGAQELMREVTKAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. CCH11-B1 TaxID=1768781 RepID=UPI00082A6CC1 ------AVVRNLGQSFSGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRITDTTTITKNDLTLHQPSAAMLKDGMTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARKMIRDIRFGPGERLLQSNYLANPPDGAAPSSIVRALAKLKQNQMLSPASSR -LLMSIMSEAKTGPRRIKGGVPPGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTQPIPARMELMQAVSRAIAA-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Anabaena TaxID=2619674 RepID=A0A1B7V0R2_9NOST ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -EGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520IWW5_SPHSX ------------------------------------------------------------- -----------------------------------AKVLELMIIRSDNYATDQILATLGGP -LAVQQWLSSHQMAGIRVDRNIAQLLRGHLADIKDVATPVAMVALLSRLDSGTVLTAQSRS -FLFGLMSRCATGTRRIRALLPAGTPVEDKTGTLD-GVTNDVGFITMPDGRRVALAVFARG -GR----DRQPVIAEVARAIYDRf ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI00136F84A7 --nALEQRISQLADGSRGRIGVYAIDLSTGQEI-GILADQRFPMASTSKVAIAATYLAGVD -AGKWSLTSEWRLPR-------------PGGALSARQHIDLMISKSCNDCTDALLAAVGGP -RAVNQWMRNAGLEEFELTRDIATLIRASSVDLRDSATPRAMGQLLAGIYQGKWLSTSSRN -VLMNAMRATTTGKKRMRSALPTGAGLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas glacialis TaxID=658225 RepID=A0A502FU42_9SPHN ---ALATSVAILARQFDGRVGIAVRSIDRGWSV-DAGGEQRLPQQSVSKLWVAMTVLDYRD -RGRLRLTDPVTLYRDDITLHQPIAGLIKGDQTTVGELLQRALTMSDNTANDRLLRYVGGP -NSVRDFIQRKGLGDIRFGPGERLLQSRYVADPPDGAAPVAIAGALARLKRGDLLSPESTN -YLISTMESSHTGKQRMRGAVPPGWSFGHKTGTGQTAGYNDVGLLMAPDGSGYAIAIMIGD -TPRPIPARQALMQAVVASVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium zucineum TaxID=284016 RepID=A0A227JQW0_9CAUL ---KLQQTLDALAENFGETVGIAIVDTSSNWIV-DVRGDMAFPQQSVSKLWVALTTLDAVD -RGVVALDQQVVLTEADRSVNQPISYRITPDGTTVADLLKRALIESDNAANDKLMGMAGGP -GAVRRLMNDKGLAGISLAEDERHLQAAYLTHPYDGAQPKALAIALAQLQAGKLLSSGSTR -WMVETMAKARTGPSRLKGGLPAGWHIAHKTGTGQRGGINDVGLITAPDGKTYAVAVFLQR -TRRPVSERLAFLQSVSRAIVAQw ->[subseq from] Carboxylesterase n=1 Tax=Synechococcus sp. 60AY4M2 TaxID=1353262 RepID=A0A2G8PCC0_9SYNE ---ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE -TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGQ -EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD -RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR -ETPNDPKAEELIAKLSQAAYEFw ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00142E390C ----------------------------------------------TSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAMPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLP--------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium sp. 1.A.4 TaxID=2044603 RepID=UPI000C0BBC57 ---KLQPKIDSILSKYDAKVGVAIHNHDLSDSL-IVNGDHHYPLQSVYKFHLGIVILDQVD -KGKLKMKDPLVFSKETMNSYSPIKDAHPNGVMPLDEVLFHTIAESDNIGCDAMFDLLGGP -KVVDTYFKKLGFKDQNIGYTERVQQAKWDIQFENWTTVSAGNHIMHAFYTNDLLSKKSYD -FLWDNMRKTTTGPNRIKGLLPKGTIVAHKTGTSGRNAINDIGVVSLPDGKVFYISVYVTD -SNEVGEPNERVVAEVSKAAYDAf ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas sp. OK281 TaxID=1881067 RepID=A0A1I5EBK6_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TVRPMPERQKLIQAAAAAVANY- ->[subseq from] Uncharacterized protein n=1 Tax=Alkalinema sp. CACIAM 70d TaxID=1934309 RepID=A0A251WAN5_9CYAN ---TLKAQIQSVLAQNKLTAGVMLADLDTQAYV-DINASETFAAASTIKFPVLVAFFQEVD -AGRATLNEMLTMTKELVADEAGEMQQPVGTKFSAIKTVTDMMMISDNTATNLIINRVGGA -AALNQRFASWGLTSTQIRNWLPDVKGT------NTTSPKDMATLFALVNEGKLVSMKSRD -RILDIMRKSQA-HSLLPKGLGEGASIAHKTGTIGE-LLGDVGLIDTANGNRYVAAVLVKR -PR-DDDRAETLIQQISKLSYQMf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Planktothrix TaxID=2648599 RepID=A0A3C1RY73_9CYAN ---DLKTAIMGLAKDSKLKPGVFLVDLDTGNYV-DIQGEEALPAASTIKVPILVSFFQAVD -EGRLRLDEVLTMAEKHIAKGSGELQDQPGSKFTALETVTLMIENSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMAEINQGKLISLKSRD -LMLRIMEQTRN-RSLLPSGLGEGAFIAHKTGNIDS-VSGDIGLIDMPNGKRYSVGVLVQR -EAN-DPQAPELIRQISSTIYQYf ->[subseq from] Beta-lactamase CARB-6 n=1 Tax=Leptolyngbya sp. O-77 TaxID=1080068 RepID=A0A110AW57_9CYAN ----LTTTLQSLVAQTGLSAGVFVVDLDTGDYV-DLNGSTVYPAASTIKTPILVAFLQDVD -RQRVRLDESLTLQTIDITDGSGEIQMEVGSQLSALDTATKMITISDNTATNMVIHKLGGL -TALNSRFRDWGMSHTVLNNLLADLQGT------NTTSARDLSLLLTAVSQGDLLSLRSRD -RLLDIMRSTVN-NNLLAATLGPDAKIAHKTGNIDS-LSGDSGIVDMPNGKRYVITALVQR -AG-DAGSAAQLIQQISQATYQYf ->[subseq from] Beta-lactamase n=2 Tax=Microcoleaceae TaxID=1892252 RepID=B5W7Y4_LIMMA ---DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF -QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR -NNGD-QAAESMIQKMSRQVYQY- ->[subseq from] serine hydrolase n=1 Tax=Arthrospira sp. TJSD092 TaxID=2153484 RepID=UPI000D3A1865 ---DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF -QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR -NNGD-QAAESMIQKMSRQVYQY- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3D1N2I1_9BACT ---NMTASLESASSAYRGHVGIYLKDLHTGKTW-QYNPDRLFPSASLIKLPIMAAVFEKIK -AGELTLDTQITLSRQNRWGGSGSLKWVRDGTLSVMEILYKMITESDNTATRMFIDHM-GL -DFLQQEFSRLGLLYTKIYPEGLSLSSG-RVRRENYTTAREMAGILERIYDGELISRDSSE -QMLEVLKHNKS-RNRLRRGLPIGWEIGHKTGLLRR-SCHDVGIIFSPRGD-YIIAVLTSN -VP-NYSSAKNFISMVAKLTYKYy ->[subseq from] Beta-lactamase n=2 Tax=Microcoleaceae TaxID=1892252 RepID=K1X8H1_ARTPT ---DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF -QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR -NNGD-QAAESMIQKMSRQVYQY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium phenoxybenzoativorans TaxID=1592790 RepID=UPI0009F212AF -----VSIIQSLGRGFNGHAGIAVKRVDADWVV-SYNGNELFPQQSVSKLWVAMNLLDNVD -RGKLKLTDSVTLGRSDLTVHQPLAAMIGKDGTTYADLFRRAMTQSDNTANDAMLRRSGGP -DAVRGFLARRFISNIRFGPGERLLQSDYLANPPDGAAPIGIVTALAKLKKGDMLSPTSTR -FLLDTMHEAKTGPQRIKGGVPAGWTYAHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQGVARAIAA-- ->[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4RY28_9CYAN ---SLKSAIQNLAIQNNLTPGVFIADLDNGGYV-DFNGGAMFSSASTIKLPILMAFFQEVD -EGKINLEETLRTSKSTVAGGSGDMQNRPGTQYGILEVATKMMTISDNTATNMLIERMGGI -EKLNQRFRSWGLNTTSLGNILPDIEGT------NKTSPKELSNLMAMITKGNIVSSQSRE -RIIDIMQRTVK-DTLLPVGLGQGAKIAHKTGEIG-GMLADTGLVELPSGKRYLISVMVQR -PRND-VSAEKLINGISRAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. SAORIC-644 TaxID=1869314 RepID=A0A2K1E876_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGELELTEKVEIRDPDLTVHQPIREIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=A0A1G7N6V5_9SPHN ------RTVQSLYAGFEGKKGIAIRAVDDGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -KGKARLDDPITVRREDLTLHQPIAYLVKGDGTTVGGLLTRALTQSDNTANDRLLTYVGGP -AAVRRMIAEKRLGDIRFGPGERLLQAAYVADPPDGAAPIAIADALARLTRGELLSETSTR -ILLETMGASRTGHARLRAAVPASWQIAHKTGTGQNAGFNDVGLLTAPDGRRFAVAVMIGD -TTEPIRNRQVLIQNVAAAVAT-- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI0011082C93 --------INKLITRYKLTPGIFFMDLETGDYI-SINGNKAFPAASTIKYPILIALFQEVD -AGRIKLNETLVMQRRYVVGGSGNMQQRVGSKFSVLKTATMMMTISDNTATNMIIARLGGI -AKLNQRFRSWGLQSTALQRMLGDFNGT------NKTSAKDLVRLSALMVNNQLLSAQSKS -QVIGIMYGCHN-RRLLPSGLGYGAKIAHKTGTLRF-VLGDAGIIETPSGKRYYAGIFVRR -PNND-DRARDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ZM42_9BACT --qKLEATIHETDQSLDGAMGVAILDLSTGQKF-LLHHDDVFPQASSIKITVLAELYRQAQ -QDKLKLTDLYTVQASDLVPDSDIMNGLTPGVITLRDLATMMVAVSDNSATNVLIDRL-GI -ENVNAFLDSLGLTHTRLRRKMMDLKAAG-EGRENIATPREMMVLLEALYRGKVLNKEMTD -DFFKMLSTHK--DSWMPRDLPEDTRVANKPGSLE-GVRNDSGIVFAKNR-PFVICVMTT- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=unclassified Synechococcus TaxID=2626047 RepID=UPI000C19D722 ---ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE -TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGQ -EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD -RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR -ETPNDPKAEELIAKLSQAAYEFw ->[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A353GXF9_9FIRM ----------QAVDFKKMNCAFIITNLRNGESA-SYNQEERVPSASLIKLPVMAETVRQVK -EGRLHLQDRVTVKAEDKVPFSILTMLETENNYSLQDLLTLMIVQSDNTAANILIQRV-GM -AKINDFCIDLKMRNTLLERQMMDLNAR-RAGRENRTTASDMARFLERLYQGELIDKASST -YMIEIMKKQLE-NSMMRLYIPDETVIAHKSGELD-GIAHEAGIVYHEKGD-FLFVVLVWN -AV-TNNEARQTIGQISKIAYDYf ->[subseq from] Beta-lactamase family protein n=2 Tax=Sphingobium sp. RAC03 TaxID=1843368 RepID=A0A1B3MR00_9SPHN ---TLVSAIRNLGQGFRGKVGIAVRRIDADWTV-AWNGTALFPQQSVSKFWVALTFLDAVD -RGKLRLTDTTTITKNDLTLHQPSAAMVKAGGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRSYLARRMIKDVRFGPGERLLQANYLANPPDGAAPTAIVGALAKLKQGDMLSAESTR -LLLTVMAEAKTGPQRIKGGVPLGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVLIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=UPI000B942B89 -htDLKKQIDEILNSYDAKAGIAIHNHDFSDSL-IINGNHKYPLQSTYKFHLGIAILDQVD -KGKLSLDQPVEFSKEMLKTYSPIKDKYPNGVLPLSEVMRYTIAESDNIGCDAMFELLAGP -DKVQEYFVEKGYTEQSIKTNEAVQQADWDIQFQNWTKVSQANKILFDYYTKNLLSESSHK -FLWDTMRSTSTGKNRIKGLLPKGTTVAHKTGYSGTAAVNDIGVISLPNGQVLYISVYVTD -SKETEPQSASIIAKVSKAAFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Roseofilum reptotaenium AO1-A TaxID=1925591 RepID=A0A1L9QXD5_9CYAN ---ALKNQIQALASQSEFKPGVFVLDLDTAGYV-DMQGTLAFSSASTIKLPILLAFFQAVD -AGTIRLDETLTLKEVHRAGGSGSLQYPVGSEYTALEVATWMMTISDNTATNIIIERLGGM -VQVNQSFSRWGLQQTVLRDWLPDLDGK------NTTSPRELAQVMAMIHQGDVVSLKSRD -RMIDIMRQTET-SVLLEQGLGAGATIAHKTGDIGK-LLGDVGLIDLPSGKRYIAAVLVER -PHND-YGAANLIGDISHLAYEH- ->[subseq from] serine hydrolase n=1 Tax=Myxacorys almedinensis TaxID=2651157 RepID=UPI0013920E67 -----------------LTPGVMVVDLDTHTFL-DINASNSFAAASTIKVPVLAAFFQEVD -AGKIRLDEMLTMRPDLIATEAGDLQYQPPGSFLALEVVTKMITVSDNTATNMIIDRLGGK -DALNQRFQTWGLTHTAIRNPLPDLGGT------NTTSPKDMATLMSMINSGQMVSSRSQA -RMLDMMRNVVT-DSLLPRGLGEGATIAHKTGDIGS-LVGDIGMVDMPSGKRYVIGVLVKR -PHND-DNAQNLIRQISTLTYQYf ->[subseq from] Class A beta-lactamase n=1 Tax=Psychromonas sp. RZ22 TaxID=2555643 RepID=A0A4Y8A114_9GAMM ------------------------------------------------------------- ------------IEEESILGYAPITSHKIGQTMSLSELCEAAMFVSDNTAANLLLKELGGP -STITVFMKILGDNTTRLDRWEPELNEATVNDIRDTTTANAMTESLYSVLFQEHLSELSRQ -QLQYWLINNKVTGSLLRSVIPQSWSIGDRSGAGGSGSRGITAVIFPDNQPAVFVAIYITQ -TKASMAQRDRAIAEIGEVIF--- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=unclassified Apibacter TaxID=2630820 RepID=UPI00135D8A41 --qSLEKKIHSITKNKKATVGVAVI-FDGKDTL-TVNNDMEYPAMSVFKFHQALALLDYMN -KNLLSLESNLYLKKSDIKKYSPLAKEYPEGNIPIGDLLNYTVSKSDNNASDALYYYMSGT -KMTDLYLRTLGSKNFSIQATEEEMSKDFNNQYINWTTPLEAARLLDIFMNKDIFCKNYKD -FLFQAMTESEPGSDKLKALLPKKVLIGHKSGSSSRNADNDIGFVYLPNGKQYSIAVFIKD -SKEDDKTNARMIADISQVVYNFy ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium sp. EP60837 TaxID=1855519 RepID=A0A173KUC9_9SPHN -------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGSALFPQQSVSKLWVSMTFLDAVD -RGKIRLSDTTTITRKDLTLHQPTAALVGNSGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSYLARRYIKDIRFGPGERLLQANYLASPPDGAAPSSIVNALAKLKEGSMLSPASAQ -LLMSIMSEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTEPIPTRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9WGK0_9BACT --qKLEAATRDLDAQLDGVMGVAIEDLTTGNHI-FLHADEVLAQASSIKITVLAELYRQAQ -QGKLKLTDLYTVQASDLVPDSDIMGGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GM -DNVIAMLDSLNLPHTRLRRKMMDLEAA-KHGRENISTPREMMILLEDIYQGKVLNQEMTA -DFFKLLSTNKS--SWIPRDLPAGVKVANKPGALE-GVRNDSGIVFVEGR-PYVICVMTTF -LR-NERDGEEAISKISLAAFRMf ->[subseq from] Carboxylesterase, beta-lactamase family n=1 Tax=Synechococcus sp. (strain JA-3-3Ab) TaxID=321327 RepID=Q2JW55_SYNJA ---ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE -TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGR -EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD -RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR -ETPNDPKAEELIAKLSQAAYEFw ->[subseq from] serine hydrolase n=1 Tax=unclassified Phenylobacterium TaxID=2640670 RepID=UPI00083AFFBC ---ALQARLDELAAAYGEEVGVAVTDVAEGWTA-GVDHERPYPQQSVSKLWVAIAVMKAAD -EGRLDPYGWVTLTGEDRSVYQPVSYRIGTGGTPISDLLRRALVESDNAANDKLMRELGGP -DGVAATLEGMGLTGVKVGAYERDLQAAYLAQPLDGAAPGEITTALAALSRGELLSPRSTE -WLIGLMTQARTGPRRLKGGLPAGWTIAHKTGTGQSVGINDVGLITAPDGHVYAVAVMMRR -TRKPVPERLAFMQSVTRAVAEQw ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YPH9_9BACL ---DLQKKIEELVGQATATFGIVIKHLETNEEV-KINEGHLFQMASCYKVPILATLFREVE -AGTIDLNTRVRLSLTDRVPGSGVLKEFDPGSVSLKDLATLMIIVSDNVGTDKILELV-GV -NRTDQYMKSIGLQDTYVNLTCWQLLSFTKSIENNVSTPADMALLLEKIARKELISKNACE -QMIDIMKRQHF-RDRIPNLLPAGTPVACKSGSVGS-VHNDIGIIYLPEEKGTVIVSAFSE -NNSSQLEAAQMIAKVAQSAYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter junii TaxID=40215 RepID=S5ZYH8_ACIJU ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDE---------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. AP23 TaxID=499656 RepID=UPI0009F9E9C7 --qRLDRELSRIGSTFAGHAGIAVRDMEARRTL-HFNGLEAFPQQSVSKLWVAMTALDEVD -EKRLDLTERVEIRARDLTVYQPIRDIVRRDGSDYADLIERAIAESDNTANDRILRRIGGP -EAVQDFLDGHGLSSIRFGTDERSKQSTYLADPVDGAPPVAIVEALARLYRGNLLSNSSTS -LLLGALSRTKSGPQRLKAGAPEDWLVRHKTGTGQQSGYNDVGLVTSPEGRSYAIAVMIAR -TREPTPLRMEMMQEVVRAVAR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium sp. CZ-2 TaxID=2557994 RepID=A0A4P7DU00_9SPHI ---KLQPKIDSILSKYDAKVGVAIHNHDLSDSL-IVNGDHRYPLQSVYKFHLGIVILDQVD -KGKLKMKEPLVFSKETMNSYSPIKDAHPNGVLPLDEVLFHTIAESDNIGCDAMFDLVGGP -KVVDTYFKKLGFKDQNIAYKERVQQAKWDIQFENWTTVSAGNHIMHAFYTNDLLSKKSYD -FLWDNMRKTTTGPKRIKGLLPKGTVVAHKTGTSGTAAINDIGVVSLPDGKVFYISVYVTA -SNEVGEPNERVVAEVSKAAYDAf ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SRK3_9BACT ------------------------------------------------------------- --------------------------------MTLGALCEAAIEQSDNTAANLLLDAVGGP -ASLTYFARKLGDQITRLDRKEPDLNSAIAGDERDTTTPGAMCLDMQRLLVASVLSESSRR -QLEDSLLRNKMGQLMIRAGVPKTWSVGDKSGRCANGATNDIAIIRPPDRAPILLAIYSVG -STAPANNREMAIAEVAKIVAELf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas oleivorans TaxID=1735121 RepID=A0A2T5FYC2_9SPHN ----LDSAITALGSGFNGTVGIAVRDVQAGWTV-AYNGGLAFPQQSVSKLWVAITLLDAVD -RGELSLDEQLLIGPRDFTVHQPIRALVGAGGTSYRSLLSLAMTQSDNTANDLLLRRAGGP -DAVRAMFLRKGLAGIAFGPGERLLQSRYLADPMDGAQPVGIVAALSRLRRGELLSIASTH -YLLGLMSSSRTGPQRLRGGLSPDWSFAHKTGTGQATGYNDVGLLTSPDGRSYAVAVMIGS -TRRGIPERQRLMQDVTRAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Geitlerinema sp. PCC 9228 TaxID=111611 RepID=UPI000AC105E1 ---SLKSQWKEIVSNYRFDVGAFLLDLDTGAYI-NLNSKASYSAASTIKVPILIAFMQEVD -AGNIQLQEKLEMKEKHVAGGSGNLQQQVGTQYTAWELASKTIAISDNTATNILIDRLGGI -EKLNQRFQSWGLQTTRLRNPLPDLEGT------NTTNPQELAKLMAWIEQGHMLTLRSRD -RLLHLMRQTEN-DSLLPQGLPSQASIAHKTGDIGS-LLADVGTIDLPNGKRYLLAVMVKR -PHNN-YVAADIIRKISQTTA--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0AK43_9BACT --qKLEAGIGEVDRDLDGVLGLAILDLSSGQKF-LLHPDDVFPQASSIKIAVLAELYRQAQ -QGKLKLTDLYTVEASDLVPDSDILGGLTPGVITNRDLATMVVAVSDNSATNVLIDRV-GM -ENVNALMDSLGLTHTRLRRKMMDVKAA-GEGRENVSTPREMMALLESIYRGEVLNKEMTD -DFLKMLSTHKE--SFLPRDLPDDVRVANKPGELE-AVRNDSGIVFAKNR-PYVICAMTTY -LR-NERGGEQAITKISALAYRMf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. EC-SD391 TaxID=2038398 RepID=A0A5E8ACG3_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS -AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQKLIQNAAAAVANY- ->[subseq from] serine hydrolase n=1 Tax=unclassified Synechococcus TaxID=2626047 RepID=UPI0002D43228 ---ALQERLAALADQPGLTAGALFWEVESGAFA-GVRPDQVFPAASVIKIPILLAFLQAVE -TGQVRLDERLTLREDLRGGGAGVLQTRPLGSVSALEAATLMSTISDNFAANLIIDRLGGR -EALNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLSRRSRD -RFLDILWRTQR-PSYFRPNLGQEVRIAHKTGTLRS-VVGDAGILDLPNGRRYVAAVWVKR -ETPNDPKAEELIAKLSQAAYEFw ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=A0A2T5GME3_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS -AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQKLIQNAAAAVANY- ->[subseq from] serine hydrolase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI00068B861E ----LRARLAAIAHTTKAEVGVSVQNLAAGQRI-EIGARTRMPSASVIKLPILAELLRMAE -RGELSLAERVHVDRSDVVGGTGQLQEKLPQDISLHRLARYMIIYSDNTATNLLIDRI-GF -GPVNALIRSLGLRSTVLERKMMDTEAQ-QHGRENYLDAADIAKLLRSLWDGRLLSAPSRA -IALGFLRDQRL-NELIPAALPPGAPVAHKTGTLDDLVTHDVGYYLVPGSE--VLVVFTTK -GT--TAAGTAAVHRMARAVWD-- ->[subseq from] Beta-lactamase n=2 Tax=Crocosphaera watsonii TaxID=263511 RepID=T2JS57_CROWT ---ALQEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFEEVD -KGNIHLDQMLTMTKDVMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK -EVLNKRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-VAGRHLIQDISRTVYQHf ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Luteibacter TaxID=2620188 RepID=UPI00068BE602 ---TLQASLQKLADQAPAKFGIIVVDLDGSASA-KVNDDRAYMLMSTFKAPVSAAVLSQVD -AGKLSLNQKVHVTPADVTAGSPSIGARAAKGVTVSELMTAAATQSDNTAVDALLKLVGGG -QVVTAYLKDKGVEGMRIDMDERAVGHAAIVMQENTTTLDGAATFLRKLQAGELLSAASTK -RLLDMMQAQVI-PNRIRAGLPAGFSIADKTGTGASNAWNDMAIITAPNGNRAVVGAFLRD -TTSTDEQRAAWFKELGTVVSK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas faeni TaxID=185950 RepID=A0A2T5U7L4_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9HM46_9BACT --qKLEAMIGGVDRNLDGVLGVAILDLTTGQNY-LLHADEVLPTASSIKIAILAELYHQAQ -QGKIKLGDLYTLQSADLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNIIIDRI-GM -ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMLLLENLYRGKVLNKQFTE -EFFNLLSIHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY -LRRE-HDGGEAIMRISNAAYQMf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y5J9_9BACL ---DLQKKIEELVGQATATFGIVIKHLETDEEV-KINEGHLFQMASCYKVPILATLFREVE -ARAIDLNTRVRLSLTDRVPGSGILKEFDPGSVSLKDLATLMIIVSDNVGTDKILELV-GV -NRTDQYMKSIGLQDTHVNLTCWQLLSFTKSIENNVSTPADMAFLLEKIARKELISKKACE -QMIDIMKRQHF-RDRIPNLLPAGTTVACKSGSVG-GVHNDIGIIYLPEEKGTVIVSAFSE -NNSSQLEAAHMIARVAKTAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E3HJW8_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVXRAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTDERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LXLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLITSPAGRTYAIAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] Serine hydrolase n=2 Tax=Sphingobium TaxID=165695 RepID=A0A0J9D3E3_SPHYA ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVEALAKLKEGDMLSSASSR -LLMSTMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVARAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Arthrospira sp. TJSD091 TaxID=1640536 RepID=UPI00061B4ADC ---DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF -QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR -NNGD-TAAESMIQKMSRQVYQY- ->[subseq from] Uncharacterized protein n=1 Tax=Limnospira indica PCC 8005 TaxID=376219 RepID=H1WII0_9CYAN ---DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF -QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR -NNGD-TAAESMIQKMSRQVYQY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ALL3_9BACT --qKLAATIKEVDGKLDGVLAVAILDLSTDQKY-LLHADEAMPTASSIKIAILAELYRQAQ -QGKVKLTDFYTLQRSDMVGGSGITRVLTPGMLTLRDVAGLMISVSDNSATNVVIDRI-GM -ENVNALLDSLGLTHTRLRRKMMDLEAA-SEGRENFATPREMALLLENLYRGKVLDQQMTD -DFFNLLSVHKE--SYIPRNLPEDLKVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTAY -LRRE-RDGGDAIAKISDAAYLMf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. JBTF-M21 TaxID=2584124 RepID=A0A547PC00_9SPHN ---AFERQIVQLADGDQGRIGVYAIDLETGKEI-SVLGDQRFPMASTSKVAVAAAFLDGVD -QGKWKLSDEFPLMIPVKSAKFSTSRAPVRTGVAAWELISLMISKSCNSCTDALLRVVGGP -KAVNAWMRDAGFDDFELSRDIATLVRVEWIDPRDSASPRTMGLLIAGIYQGRWLSQQSRG -LLMAALEETTTGRRRMTAALPESARLAHKTGTLSR-TASDIGIFRLPDGRAVAAAIYVTG -QSANRKKRDERIAAITRALYNGf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8YV12_9BACT --qKLAAAVNEVDSKLDGVLGVAILDLTTGQKY-LLHPDELMPTASSIKIAILAELYRQSE -QGKVKLTDFYTLQQSDMVGGSGITSVLTPGMLTLRDVAGLMVSVSDNSATNVIIDRI-GL -ENVNALLDSLGLTHTRLRRKMMDLKAA-SEGRENLATPREMMLLLENLYRGKVLNKQMTE -DFFNLLSVHKE--SYIPRDLPEAIKVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY -LKRE-RDGGDAITKISDAAYQMf ->[subseq from] serine hydrolase n=1 Tax=Limnospira indica TaxID=147322 RepID=UPI0012FA23D2 ---DLKTQLELVAAASDITPALMFLDLNTGGYV-GLREQSKVPAASTIKVPILVAFFQAVD -AGEIRLDEMLVMTENHQVGEAGIMQYQPPGTYTALATATKMMTISDNTATNMIIERLGGF -QVLNQKFRSWGLTDTLVRNPLPDIEGT------NQTTPRDMVSLLSQIHQGGLLSMTSRD -RLLRIMTETEN-NHLLPSGVSNGAVVAHKTGTLNI-MLADVGIVDMPNGKRYILAILAQR -NNGD-TAAESMIQKMSRQVYQY- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A2D8MGN0_9SPHN ---ALQQQLRDLGETFNGDVGIAVTQADTLATM-SYSGKKRFPQQSVSKLWVSLTALDLRD -EGALDLSEPVRLRAEDLTVHQPLRNIVRARGTDYADLINRAITQSDNTANDRLLRRVGGP -SAVEGFLRRNQISGVQFGTDERTKQSAYLADPIDGASPVGITKALARLARGDLLSENSTD -LIVSTMQRTRSGPRRLKGGVPAGWTIAHKTGTGQQSGYNDIGILTAPDGTNYTMAVMIGS -TRASYAARMGMMQEVTRSVVRY- ->[subseq from] Beta-lactamase class A n=1 Tax=Propionispora vibrioides TaxID=112903 RepID=A0A1H8PNC5_9FIRM --kQLEQTIQQILTTCPCQQALLIRHLPSGRQF-ALNPDQVFPAASMIKLPIMYEVMRQAS -QGRLALEELLEVTEAVRVGGAGILQERPGIALTVQELVTLMIVISDNTATNLLLNRI-GL -AAVNSTAEQLGLTNTVLRRRMMDFTAA-RAGQENHTSVADIAKLLEIMYQQTTLPPEYGE -LMLNILKRQQI-RDKLPFYLPEDIAIAHKTGTLD-GVEHDAGILFSAGG-PYLISVMTAD -LPVN-YQGLQLVAQIGRAIFEY- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:144 TaxID=1262736 RepID=R5YBD0_9BACE ---DIQLAIHSVINDKRATVGIAIL-CDDGNMV-VMNDDERYPVMSVFKFHVVVTALKKME -QHGIPLDSMTLIPQEQMLSYSPLREKYPNRDISYRNIIRYTMAHSDNNTCDFLIDFVGGI -SVVDSLIRQLGINKFAFSETEKTMHENILNCYNNWCTPSSMVLFLKKIYTEPILNNDHFL -FLEQVMIETSTGTNKIKAGLPADVILGHKTGSSDRTGDNDAGIIYLPHNKRCYIAIFIKD -SKENDTANAKIIADITEKIYE-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XBW0_9BACT ---DLSNRLTTLAKSLGDEVALSVVHVESGRAV-AVEGAKKLQLYSVFKVPLAIAVLKAVE -EKKLSLDQKVHVTPGDVAPGSQFNTDLWRQPKSVAELLEFSIVRSDNTSSDKLLGLVGGP -AGVTQRMRALGYSDIDIVSTVRGYASK--QGNPNVGAPVDLARLLTQLQKGELIQPANAL -LLLGFMERARTGERRLRASLPPGTPVADKTGSGT-AATNDIGVITLPDSGHLAIAVLING -TKSKTEAQEKLIAEIARAAYDAf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D4Y597_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP49 TaxID=1144307 RepID=J2W8N5_9SPHN ----LVSVIQNLGQSFRGKVGIAVRRVNSDWTV-AYNGSALFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITKKDLTLHQPSAAMVGATGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVEALAKLKEGDMLSSASAR -LLMGIMEEAKTGPQRIKGGVPHSWSYLHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVAKAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D9X7Q1_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. Z007 TaxID=627495 RepID=UPI000B4A42CC -------VVRNLGQSFNGKVGIAVRRIGADWTV-AWNGTALFPQQSVSKLWVAMTFLDAVD -RGKLRITDTTTITRNDLTLHQPTAALVAKEGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNQMLSPASSR -LLLSIMAEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGASYAVAVMIGS -TTVGIPERWALMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9UN96_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYB2_FULL_62_6 TaxID=1797970 RepID=A0A1F9ZDY1_9BACT ----MVTSLENTAYNYRGHVGIYLRDLNSGRTW-EYNADRLFPSASLIKLPIMAAVFDKIK -TGALSLDTQIKLTRRDRAGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDYA-GI -NYYQLTFEKLGLVYTRIYPEGLSLTSG-RVARENYTTAREMSVLLERIYRGDLVDRASSE -AMLEFLKQNK-GRTRLRKGLPIGWEIGHKTGLLRK-SCHDVGIVFSPRGD-YIIAVLTGD -VP-DYTSAKSFISKVAKLTYEYy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Methylomusa anaerophila TaxID=1930071 RepID=A0A348AGG3_9FIRM ----LHRNIERILTAYTGRWGMVIVNQSTGARL-ELNPEMVFPAASMIKVPIMYEIMRQAA -AGTISLDDSLTVTSCFRTGGAGILKERPGLTLTVRELVTLMIILSDNTATNMLIDLA-GM -EAINKTITGLGLKSTVLRRRMMDFDAALA-GKENYTSAADLALMFANIYHSRGLPESYGA -LMMDILTRQQI-RDKLPFYLPAKTVMAHKTGTLT-GVEHDAGILFLPGG-PYIICVLTGD -LAAN-QQGIQLVASIGKVIYEYf ->[subseq from] Beta-lactamase n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3L3H0_9BURK ------------------------------------------------------------- ----------------------------------AAKVMELMIIRSDNQATDQLLTTLGGP -AAVQQWLLTQKIAGIRIDRSIAQLLRDHLADSKDVATPVAMVTLLTKLDNGTILTAQSRA -FLLDLMNRCATGTRRIRALLPAGTRVENKTGTLD-GITNDVGFMTMPDGRRVAVAVFARG -GR----DRQPAIAEVARVIYNRf ->[subseq from] Beta-lactamase n=1 Tax=Crocosphaera watsonii WH 0003 TaxID=423471 RepID=G5J769_CROWT ---ALQEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFEEVD -KGNIHLDQMLTMTKDVMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK -EVLNKRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-VAGRHLIQDISRTVYQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=A0A0P1LDV6_9BACT -hkKTFEKIKFIADTSNGVIGVAVKNLETGETF-FINENLIFPQGSAIKIPILIEVIKQAS -EGKFKLTDKIKIEKKHQVGGSGVLKEFGDGTLSIYDLAVLMITVSDNTATNILIDLV-GM -ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPLEAMKLMEMLYKGEVISKEISN -QVIDILKKRKE--ANLNKYLPEDIPIANKPGGIE-GVTCEWGIVYLPRH-PYVIVVMSNY -NL---KSANETIAQISKIIYEHf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. YT30 TaxID=1735012 RepID=A0A125QJL3_9SPHN ---SFEQRIAELADGNLGRIGVYAVDLATGEEI-SVLGDQRFPMASTSKVAVAATFLAGVD -EGRYSLTSEYPLLIPVRSKKFSSEKAPVRTGVPAYELISLMISKSCNSCTDALLKAVGGT -EEVNKWMRQAGLSDFELSRDIATLVRVEWIDPRDSATPRVMGQLLAGIYQGRWLSANSRN -LLIGAMEETTTGRRRMNAALPDAAALAHKTGTLTR-TASDIGIFRLADGRAVVAAIYVTG -QSASRAKRDARIADITRALYNGf ->[subseq from] class A beta-lactamase n=1 Tax=Luteibacter sp. 9135 TaxID=1500893 RepID=UPI000691093A ----LQASLQSLADKAPAHFGIIVTDLDDGTTA-RVGDDRAYMLMSVFKAPVAAAVLHGVD -AGTLHLDQRVHLTPADVVAGSPSIGTRAAKGVTVAELLSASVSQSDNTAVDALLKLLGGG -PKVTAYLDGKGVHGMRIDVGEREIGQAAIAMPQNTTTLDGAATFLRKLQAGELLSPVSTR -YLLSLMQAQVV-PTRIRAGLPAGFGIADKTGTGAYGAWNDMAIVTAPNGKSAVVAAFLRD -TTSTDDERAAWFRELGALVAA-- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=A0A4Y1WWV8_9BACT ----LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD -SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLRYTVAESDNCACDRLIREIGGI -GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD -FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE -TALSDGETAALIAEISRLVWQ-- ->[subseq from] Beta-lactamase n=1 Tax=Pelosinus fermentans B4 TaxID=1149862 RepID=I9AWU6_9FIRM --kELQKKIEATLAAYRGRWGMVILNHSSGQHF-TINPDMVFPAASMIKIPIMYEAMRQAA -AGRIDLEQLLIVKDELRVDGAGILKERPGISMTIRELVTLMIILSDNTATNMLIDLL-SM -SAINQTMERLGLKSTVLRRQMMDFAAA-AAGQENKTSSADIIRLLTIIYDHSHLPADYGK -LMIDILSRQQV-RDKLPFFLPEEIVIAHKTGTLP-GVEHDGGILFLPGG-PYIICIMTAD -LPAN-VEGLQLVAALGKVIYEHf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium baderi TaxID=1332080 RepID=T0G5V3_9SPHN -----VSVIRDLGQSFNGHVGIAVRRVGAGWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD -RGKLRLTDTATITRQDLTLHQPSAAMVGATGTTYGNLMNRAMTQSDNTCNDALLRAVGGP -DAVRGFLARRFIGNIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSASSTA -TLLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingobium wenxiniae (strain DSM 21828 / JZ-1) TaxID=595605 RepID=A0A562KN23_SPHWJ -----VSVIRDLGQSFNGHVGIAVRRVGAGWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD -RGKLRLTDTATITRQDLTLHQPSAAMVGATGTTYGNLMNRAMTQSDNTCNDALLRAVGGP -DAVRGFLARRFIGNIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSASSTA -TLLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A5P6NFH9_9SPHN --rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRAADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9HR12_9BACT --qKLEVAIKDVDRNLDGVLAVAILDLSTGQKY-LFHADEVLPTASSIKIAILAELYHQVQ -QGKLKLGDLYTLQSSDLVGGSGVAGALTPGVLTLRDVAALMISVSDNSATNVIIDRI-GM -ENVNALLDSLGLTHTRLRRKMMDVKAA-AEGRENIATPREMMILLEDLYRGKILNKQMTD -DFFELLSIHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGHR-PFVISVMTTY -LHRE-KDGGEAIIRIATAAYQMf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V582_9BACT --------------------------------------------------MAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGPPASWVV---------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=UPI001143AEB9 ----LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD -SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLRYTVAESDNCACDRLIREIGGI -GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD -FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE -TALSDGETAALIAEISRLVWQ-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0002898F93 ------------------------------------------------------------- -----------------------------------AKVMELMLVRSDNIAADQLLATLGGP -MAVQQWLWSHKITGIRVDRTIAQLLRGHLADSKDVATPVAMVALLYKLDNGTILSAQSRN -VLFDLMGRCQTGTRRIRALLPVGTRVEDKTGTLD-GVTNDVGVITMPDGRRVAIAIFARG -GR----DRQPVIAEVSRVIYDRf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Erythrobacter sp. RIFCSPHIGHO2_12_FULL_63_10 TaxID=1797975 RepID=A0A1F9ZDR3_9SPHN ---SFERRIAQLADGRQGRIGVAAIDLTTGRQI-AVLGDQLFPMASTSKIAVAATFLEMVE -QDKYSLTSEFALLLPVGSAFSSAAAPVRKGEMPAIDLIELMITRSSNPATDALLAAVGGP -AKVNDWVRRQGIKEFSINRDIATLVRAAHIDKRDAATPLAMVELLGGLYQGKFLSDESRR -VLLGAMSRTRTGKRRIPAQIPLEAQVSHKTGSLNN-TSSDVGIIQTPDGRAIALAVYVTG -H---------------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3D6EAV0_9PORP ----IQLAIHSVINDKRATVGIAIL-CDDGNMV-VMNDDERYPVMSVFKFHVVVTALKKME -QHGIPLDSMTLIPQEQMLSYSPLREKYPNRDISYRNIIRYTMAHSDNNTCDFLIDFAGGI -SVVDSLIRQLGINKFAFSETEKTMHENILNCYNNWCTPSSMVLLLKKIYTEPILNNDHFL -FLEQVMIETSTGTNKIKAGLPADVILGHKTGSSDRTGDNDAGIIYLPHNKRCYIAIFIKD -SKENDTANAKIIADITEKIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9SXA3_9BACT ---KLEASIADVDRNLDGVLGVAIEDLTTGQKY-LLHADDVFPQASSIKIAVLAELYHQAQ -QGKLKLTDFYVVQSSDLVPDSDIMGGLTPGVITLRDLATMTVAVSDNSATNVLIDRV-GM -ENVNALMDSLGLRHPRLRRKMMDLKAA-SEGRENVATPAEMMTLLEDLYRGKVLNKELTD -DFFRMLSTHKN--SFIPRDLPEGLKIANKPGELE-GVRNDSGIVFVDNR-PYIICVMTTY -LRR-ERDGEEAIRKISLETYRMf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E6RWE6_9SPHN --qELDREISRIGGTFAGHVGIAVHDIEAXRTL-HFNGLERFPQQSVSKLWVAMTALDEVD -AGRLDLAEMVEIRSRDLTVYQPIRKIVRRKGSDYADLIARAIXESDNTANDRVLRRVGGP -EAVQDFLDGHGLASIRFGTDERTKQSTYLADPPDGAPPVAIVEALARLYRGXLLSEXSTR -LLLDTLEQTKSGPRRLKAGAPEGWTVRHKTGTGQQSGYNDVGIVXSPXGRXXAXAVMIAR -TREPTPTRMEMMXXVVRAVVRY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium cupriresistens TaxID=1132417 RepID=A0A4Q4JL21_9SPHN -------VVRNLGQSFHGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPSAALVAREGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKEGQMLSPASSR -LLLSIMAEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGYNDIGIMSAPDGANYAVAVMIGS -TTVSIPERWALMQAVAKAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium czechense LL01 TaxID=1420583 RepID=A0A0J7XS53_9SPHN -------VVRNLGQSFHGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPSAALVAREGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKEGQMLSPASSR -LLLSIMAEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGYNDIGIMSAPDGANYAVAVMIGS -TTVSIPERWALMQAVAKAVVA-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Sphingobium TaxID=2611147 RepID=W1RXZ6_9SPHN ------SVIRNLGQSFHGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTITRNDLTLHQPSAALVAKDGTSYSDLMRRAMTQSDNTCNDALLRAAGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPSSVVAALAKLKQGDMLSPASSR -LLLSIMEEAKTGPKRIKGGVPAGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. PAMC28499 TaxID=2565554 RepID=A0A4P7QMK1_9SPHN ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR -VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] Beta-lactamase class A n=4 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A084EQW9_SPHYA ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR -VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A177J307_SPHYA ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR -VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2D9PAZ4_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3D0WLM1_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9P5K5_9BACT --qKLEASIAEVDHNLDGVMGVAIEDLTSGQKY-QLRENEVFPQASSIKIAVLAELYRQAQ -QGKLKLTDLYVVKSVDLVEDSPIMNGLTPGVITLRDLATMVAAVSDNSAANILIDRV-GM -ENVNSFLDSLGLAHTRLRRKMMDLKAAG-EGRENISTPGEMMTLLDAIYRGKVLNKSLTD -DFFKVLSTKKN--SWIPRDLPENLKIADKDGELE-GVRNDSGVIFLENR-PYILCVMTTY -LRRE-RDGEEAISKISV------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=A0A0Q4JKN4_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS -AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQKLIQNAAAAVAT-- ->[subseq from] class A beta-lactamase n=1 Tax=Salmonella enterica TaxID=28901 RepID=UPI000578EE57 ----------------GARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -XGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTT------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=A0A085K7G9_SPHYA ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR -VLMNFMQEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Hormoscilla sp. GUM007 TaxID=2480854 RepID=A0A533NMJ2_9CYAN ---SLRQDVQTLASANELIPGVFILDLDRGAYM-EVNSSSTFAAASTIKLPILVAFFQDVD -AGLLRLDEQLTLRREHVATGSGSMQYHQGTQYSALEAARMMMTISDNTATNMLIEGLGGI -DVLNQRFESWGLRRTVVRNPLPDLEGT------NTTNPRDLAYLMARINQGSLTSGRSRD -RMLEIMGRTET-TPLLKPGLGEGATIAYKTGNIGS-MIADVGLISLPNGKRYIAAVMVNR -PFND-DRARELIAQISRAAYR-- ->[subseq from] Beta-lactamase class A/beta-lactamase class A VEB n=2 Tax=Sphingobacterium sp. JUb20 TaxID=2485110 RepID=A0A4R3AHA3_9SPHI --qQLQERIKHIIDTTGGNIGVGVQGMDFKSGF-IINGNHEYPMMSVFKFPLAFAILDKVD -KGELKLSDKFHMPKASLDTWSPMVKDFPNQDVTLADLLTYSVSKSDNNACDFLYTKVGGP -VEVNQYLHYAGVKDISIVYTEGEMEKDWALQYKNWCKPAGAIRLLQLLYNQQLLSKTSND -FLIQIMRELPDWGKRITVLLPPTAELIHKTGASGMAAFNDIGIITLPNGQHLAIAVFVSD -FNAPQQRGINVIAAISKEIWDYy ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter gangjinensis TaxID=502682 RepID=A0A1J0VAC9_9SPHN --eELEATLQDIGKDFGGSLGIAVVDVEQDWQA-GFNADTVLPQQSVSKTWVALTAMVMAE -AGELDLDAPIRVTREDLTLHQPIRKEILRDGTDHADLIERAIQQSDNTANNALLQRVGGP -EAIRAMLAEQGLEGIRFGPGEKPMQASYLADPVDGASAAAIAQAFAAIVRGDVLSEEGAD -TFLTIMANTRSGPRRLKGGREDGWVVSHKTGTGQQSGYNDVGVLFAPDSTPYAVAVMIGV -TERPTPERMEMMQSVTRAVIAY- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014481CC4 --------------NADLIPGVFLLDLDNGGYV-DINSNASFAAASTIKIPILIAFFQDVD -AGKIRLDEMLTLEKEMIAGGSGNMQYQPPDSYTALDVATKMMTISDNTATNMLIAKLGGQ -EVLNGRFRSWGLTTTMIRNPLPDLPGT------NTTSPRELGNLISMVNQGSVVSMRSRD -LILNIMSRTQR-DNLLPAGLGKGASAYHKTGDIGT-MLGDAGLVDVPTGKRYIAAIMVQR -PHND-PRAGKLISSISSAAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9) TaxID=1198114 RepID=E8X484_GRATM ----LRQQIRATAEQAKGKVSVACSLPGTLLDC-DLHPDAHPPMQSVFKLPLGMAILDQVQ -RGRFTIDQPIRFLASDRIPYSPLQDEFPQADVPLRELLRLSVSLSDNCAADVLLRILGGP -KVLQAYIDSLGIEGFHIQDDEAGLHQDVLAQYRNWFEPSAAVALLRLINDRPPFSRQNTA -LLTGWMKTPPDRPSRVAQALPKGIEVLHKTGTSDY-ATNDIGLITLPDGRRLAVAVFVTD -ASADTATRDRVIAEISRQIYD-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingomonas mucosissima TaxID=370959 RepID=A0A245ZFJ8_9SPHN ---ALLNAVQALGQSFNGDVGISVRDVEEGWTV-AWAGDKPRPQQSVSKLWVAIALMDAVD -RGRLGIDHSVTVRQSDLTLHQPIRPLVGKDGTTIGDLLHGAMTRSDNTANDVLLWRVGGP -DTVRRTLAEKGVAGVTFGPGERLLQARYLADPEDGASANGVTLGLALLAQGKLLSPASTE -KLLSLMRASKTGTLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLIVAPDGHRYAVAVMIAS -TRQPIPARMRLMGDVSRAIVS-- ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter marinus TaxID=874156 RepID=A0A0H0XM52_9SPHN ----LATEIDRLALEFGGSTGIAVIDIKNGWST-GFEEEKILPQQSVSKLWVAITALEHAD -RGELSLSDKVRLTRDDLAVHQPIRARILNEVIDIAELIERALTESDNTANDAVLNAIGGP -DAVRAMLAKKEMIGIRFGPGERMMQSSYQSNPVDGATPLAIASALARLSRAEILSAGSRD -WLISVLRRTKSGPNRLKAGVPDGWEIAHKTGTGQQSGYNDVGLLLAPDGCNYAVAVMIGE -TRRETPDRMELMQGVARAVAEY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=A0A4Y1XN26_9BACT ----LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD -SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLHYTVAESDNCACDRLIREIGGI -GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD -FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE -TALSDGETAALIAEISRLVWQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=A0A4Q7SK71_9SPHN ---SLVNAISELQSGFQGKAGIAVRAVDDGWTV-EAGGRQLLPQQSVSKLWVALTVMDLRD -QGRIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGDLLTRALTHSDNTANDRLLTRVGGS -AAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TIRPMPERQKLIQNAAAAVANY- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SD-21 TaxID=161528 RepID=A5PA76_9SPHN --sALERTVAQLADGSRGRIGVYAIDLSTGQEI-GVLADQRFPMASTSKVAIAAVYLAGVD -AGKWTLSSEWRLPR-------------PGGALSAQQHLDLMISKSCNACTDALLDAVGGP -RAVNAWMRKAGIEEFQLDRTIASLVRASSVDLRDSATPRAMGQLLAGIYQGKWLSPSSRA -VIMNAMRATTTGKKRMRSALPVSAGLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG -QSSSMAAEN-------------- ->[subseq from] Beta-lactamase n=1 Tax=Methylibium sp. T29-B TaxID=1437443 RepID=W7WML0_9BURK ------------------------------------------------------------- ------------------------TEAYADGELTLAQLCHATITTSDNTAGNLILASYGGP -QALTQYARQLGDKITRLDRNEPDLNTRVEGGSLDTTSPRAMAMTMNKLLLGDALSPLSRN -LLRQWLLENTTGGKRLKAGTPADWTVGDKTGTNKT-DANDIGILLPPQGAPVLVTAYLAD -STASSQIKDATLAEVGRL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. AP50 TaxID=1884369 RepID=A0A1H6SQ95_9SPHN ------NVVRNLGQSFRGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLADTTTITRNDLTLHQPTAALVAQNGSSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKQNEMLSSASSR -LLLSIMSEAKTGPQRIKGGMPPGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. UWO311 TaxID=2487337 RepID=UPI001157724E ------SKIKDLAKEKDLSMQMMVVDLDSGAYV-QVGANQSIAAASTIKTPILVAFFQDVD -AGKIKLDEPIEMTADVKVGEAGDFQFLPTGTISALEVATQMIVISDNTATNMIIKRLGGT -SVLNQRFKSWGLNNVVVNNQLPDLEGT------NTISTQDMVSLLAMLDKGKLIEPRSRD -RFMDIMRRPVT-NTLLPKGIGENARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQVSRATYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. HMF7854 TaxID=2315330 RepID=A0A3R9Y4P2_9SPHN ------------------------------------------------------------- ---------------------------------SAARLMDAMLIHSNNVATDMLLRNLGGP -SAIQAWLNQHQVKGMRMDRTIAALLAARRWDVRDSTTPEAMVQFLRRLDSGDFISPSSRA -YLLGVMSRCETGKNRMKAFLPYGTKVEHKTGTLN-GLTGDVGFITMPDGRRVALAIFARN -GN----NRPRTIAATALAIYEGf ->[subseq from] serine hydrolase n=1 Tax=Phormidium sp. HE10JO TaxID=1765956 RepID=UPI000B400A99 ----LDSQLQELLGQYELTPGIMVVDVATGDYV-RIGEGSVFAAASTIKVPILVAFFQAVD -AGQVQLEERLRLEESHIQGGSGSLQYEAPGLLSALEVATLMIVESDNTATNLLIDRLGGF -AALNDRFRQWGMRETVLEDWLPDVQGT------NQTTPEELAGLLGQIERGELLSMGSRD -RLLRIMMMTEN-DTLLPQGLGTGAVIAHKTGNLR-GVLADAGLVDVPNGQRYVVVALVER -PEYD-DRAVELIRELSARVYGYf ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter gangjinensis TaxID=502682 RepID=A0A0G9MQS7_9SPHN --eELEATLQDIGKDFGGSLGIAVVDVEQDWQA-GFNADTVLPQQSVSKTWVALTAMVMAE -AGELDLDAPIRVTREDLTLHQPIRKEILRDGTDHADLIERAIQQSDNTANNALLQRVGGP -EAIRAMLAEQGLEGIRFGPGEKPMQASYLADPVDGASAAAIAQAFAAIVRGDVLSEEGAD -TFLTIMANTRSGPRRLKGGREDGWVVSHKTGTGQQSGYNDVGVLFAPDSTPYAVAVMIGV -TERPTPERMEMMQSVTRAVIAY- ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI000289E520 ----LTATITQLVRSFNGKVGVAVRSVDDGWMI-NAGGSQRLPQQSVSKLWVAMTVLAARD -AGKLRLDDPITLTRDDITLHQPIAGLIRGDTTTVGELLQRALTMSDNTANDRLLRLVGGP -TAVRGFIARKGLGAIGFGPGERMLQARYVAAPLDGAAPAAIATALARLKRGEILSAPSTS -YLIGTMQSSHTGKMRLRGAVPPGWTFGHKTGTGQTAGYNDVGLLIAPDGRTYAIAVMIGD -TLRPIPARQQLMQAVVSSVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Sphingobacterium sp. dk4302 TaxID=2662364 RepID=A0A5Q0Q6T5_9SPHI --aQLKKDIETILSKYKAKVGIAIHNDDYTDSL-TVNAEHHYPFQSVYKFHLAIAVLNQVD -LGVLKLDQPITISKAAVTTYSPIKEQYPNGVLPLSKVIDFTVADSDNVGCDILFELLGGP -DKVQAYFIANGYQDLSIKLTEEVQQKDWEKQFQNWTTVGSSNKILYDYYRKHLLSETSHQ -FLWDTMRGTRTGLNRLKGDLPPGTVVAHKTGYSGTAAVNDIGVVSLPNDKVFFISVYVTD -SKEEEPVSAKIIAEVAAATWKY- ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium I41 TaxID=2528024 RepID=A0A517U3H2_9BACT ---ELAELIQPLIDAHQGDVAVAVKDLNTGETF-EHQAHKTMPTASLIKFPLMIAAYQAIE -EGTADPATLIELKESDKVPGSGILTTHFSDGISLRDAIQLMIVYSDNTATNLVANEV-GL -DKTAALMEKLGYPETKLHSFVFKRESRSVKFGLGSSTPADMASLLEKLQKKELVSQEASE -KMLGHLYACAD-KSTFPRNLP-NVKIAHKTGATNE-VRTDAGIVDGPKG-PIVLCVMTNE -NRDQENAGDVLCSKIAQAVYQHf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012450F69 ------------------------------------------------------------- -------KEKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Similar to Beta-lactamase class A n=1 Tax=Crocosphaera watsonii WH 8501 TaxID=165597 RepID=Q4C1V5_CROWT ----LQEKIQKIDAKYNVKPQAWFIDLDNGSYV-TYNGTQPVPAASTIKIPVLVAFFEEVD -KGNIHLDQMLTMTKDVMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK -EVLNKRFKEWGMKNTEINNILPELEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-VAGRHLIQDISRTVYQHf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI0013281191 ----------RWAERWGGTLGAAVHDLGTGERA-EAAAGRSFTSASVIKVPLLAALLAGAE -AGDWSLDDRLPVGPRARVGGSGVLKDLADVPLSLRDLATLMIVLSDNTATNLLIDLV-GF -AAVNAWCARHGLRGTVLARRMLDADAR-ARGDENLTTAGDMAALFTGLVRGDLLGERSST -FALDVLARQQV-NDRLPRHLPDGARLAHKTGELP-GVRHDAGVVLPEGRAPIVVVVLTEG -VTDPRDRAADLIAETGRAVY--- ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=UPI0011450B34 ----LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD -SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLHYTVAESDNCACDRLIREIGGI -GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD -FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELPDGSGYAICVYVAE -TALSDGETAALIAEISRLVWQ-- ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3TYU4_9CAUL ----------------------------------------------------------RVQ -REEEQLDRAVAVTRADMIPHAPVTEKAIGRTLTIRELMQAAVEVSDNPAANILIREMGGI -AVWRSWWPTFGDTTTVISRLEPDLNTALPNDPRDTCLPDQTIANIRELAFSDRLTPEHDQ -LISGWMIASPTGANRIKAGAPEGWTVAHKTGTGANGATNDIGMLTPLSGSPVLLAAYFTG -APATDDQRDAVIAEATRRALK-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9B022_9SPHN --rELDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLHEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGQQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQDIVRAVVNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium mizutaii TaxID=1010 RepID=A0A239XUR4_9SPHI ----LKPQIDQVLANNKAKVGIAIHNDTFTDSL-IINGDYPYPMQSTYKFHLAIAVLDQVD -KGKLTLGQPVEISKETVSTYSPIKDKYPNGTLPLSEIIRYTVAESDNVGCDIMFGLLGGT -EQVQKYFEEKGYSEQSIKTTEEEQQANWDIQFQNWTKVSQANRILFDYYSKKLLSDSSHK -FLWDTMRSTSTGKDRLKGLLTQGTVVAHKTGYSGTGAVNDIGVIELPNGKVFYISVYVTD -SKETEPNSAKIIAEVSKAAYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CC-3G-468 TaxID=2135656 RepID=A0A4R1U4P4_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAITVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. UNC305MFCol5.2 TaxID=1449076 RepID=UPI00068954B7 ---ELVTSLDGITRNFNGLVGVAVTSIDDGWTAsNVTASRPLPQQSVSKLWVTMTVLDAVD -RGEIRLDDPLTITRADFTLHQPVAALVKGDVTTVAEIMRRAMQMSDNTCNDKLLRLVGGP -QAVRDFIARKQLGTIRFGPGEKLLQAAYVKDPPDGAAPASIADALARLYRGELLSANSTA -WLLATMDGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAIAVMIGD -TSRPIRERQLLMQAVASAIVAH- ->[subseq from] Beta-lactamase n=1 Tax=Planctomycetales bacterium TaxID=2053591 RepID=A0A5K7XL11_9BACT ---DLADVVQPLIDAHRGDVAVKIKDLATGETF-EYHADKTMPTASLIKFPLMIASFQEFE -EGNVAPEAIVELDEKDKVPGSGVLTAHFSGGMPLRDAIRLMIVYSDNTATNLVAKKV-GL -DKTAKLMEKLGYPETKLHSYTFNRPSRSVKYGLGSTTPADMVSLLEKLWKKELVSKEASE -KMLTNLYACAD-KSTFPRYLP-DVKFAHKTGATEL-VRTDAGLMELPSGGPIAMCVMTNE -NKSPNNEGDVLCSKIAQAVYRYy ->[subseq from] Serine hydrolase n=2 Tax=Novosphingobium ginsenosidimutans TaxID=1176536 RepID=A0A5B8S5E3_9SPHN ---ALQAELSRIAASFEGQVGIAVTKAGCDWTV-GARLDQHFPQQSVSKLWVAMSVLDAVD -NGRMRLDQQITITPRDLTLNQPLQWEVLDKGRPVQMLMANALSLSDNTANDRLLWTVGGP -NHVRAFLKSREIAGIRFGPGERLLQSKYVADPMDGATPAGMAQALARLAKGELLSEQSTK -LLLDTMGKSRSGPMRLKAGLPPGWKAFHKTGTGQATGYNDVAVVEAPDGSYYGVAVLIGQ -THQPIRARMEMMQSVSAALA--- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Aminicenantes TaxID=910038 RepID=A0A1F5AFQ7_9BACT -------------------LGVALKDLKTGRTF-LLNEREVFPQASSIKIAVLYEMFKQAE -EGRLKLDEFIIVDEGRKVEGSGVLFYLGRPRLSVRDLAVLMVVLSDNTATNLLIDKV-GM -EAVNKRMDALGLSKTRLRRKMMDLKAA-AEGRENVSTPLEMMTLLEKIWKGGILGESYRK -DLLAILAIPKD--SPLRAGVPEGVEVAEKPGELE-AVRCDSGIVMLTGR-PYVLCVMTTY -LKRD-ADGNPAIAKISRIVYEH- ->[subseq from] Beta-lactamase n=1 Tax=Nodularia spumigena CCY9414 TaxID=313624 RepID=A0ZAJ6_NODSP ------DAVQNLAIASNLRPGVFLVDLETGGYV-DVNSSATFSAASTIKVPILIAFFQDVD -AGKVRLDEMLRMEKEMVAGGSGNLQQQVGTQYSALELATQMSASSDNTATNMLIARLGGM -EALNQRFLRWGLSATAIRNPLPDLPGT------NTSSPRDLGNLLAMVNQGNLVSMRSRD -LILDIMRRTER-NHLLPSGLGAGARVYHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR -PNND-PLAEKLISAISGAAYQQf ->[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena frigida TaxID=945775 RepID=A0A2W4Y874_9CYAN ------SKIKELAKEKDLAMQMMVVDLDSGAYV-QIGANQPISAASTIKSPILVAFFQDVD -AGKIKLDEQLEMTADVKVGEAGELQLLPTGTISALETATQMIVVSDNTATNMIIKRLGGF -AALNQRFKSWGLNNIVVNSQLPDLEGT------NKISTQDMVSLLAMLDKGKLIEPRSRD -RFMDIMRRPVT-NTLLPKGIGEDARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRVTYDYf ->[subseq from] Uncharacterized protein n=2 Tax=Bhargavaea cecembensis TaxID=394098 RepID=A0A163FIZ0_9BACL ---SLQGKIEKLLGETSARFGVSIRHLQSGEEV-RIRADERFQMASVFKVPILLSLYEQVH -EGRIDLTTRVALTKEERVPGSGILQELDPGLVTIKDLATLMTIVSDNMATDVLLGML-GK -EDVQETMKRIGAENISIVHSCWELLSMRTDLENNLCTPDDMTAILTKLAEGAFIDPAVSG -AVLDILYRQQL-NDRIPGRLPAGMPVAHKTGTIAS-AINDAGIIGLPGGGPLVVSIFSAD -NP-TTESGEAVIARIAETAYRHf ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A521PQP0_9CAUL ---ALQARLDELAAAYGEAVGIAVTDVEAGWTA-GVDQDRPYPQQSVSKLWVAIAVMKAAD -EGRLDPYGWVTLTDADRSVFQPVAYKIGSSGTPISDLLRRALVESDNAANDRLMRELGGP -DGVAATLQDMGLKDVKVGAYERDLQAAYLAAPLDGAAPAAITAALAALSRGELLSEASTG -RLIGLMEQARTGPRRLKGGLPAGWSIAHKTGTGQSVGINDVGLITAPDGHVYAVAVMMRH -TRQSVPARLAFMQSVTRAVAEQw ->[subseq from] serine hydrolase n=1 Tax=Sphingomonadaceae TaxID=41297 RepID=UPI00065C8420 ---DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-AFNAERMLPQQSVSKLWVAIAVMDAVD -RGKLSLSDPVTVKKSDLTVHQPIRSLVTKAGTTVGKLLELAMTRSANSCNDVLLWKVGGP -QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSARSTR -HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGHRYAVAVMIAS -TRLPIPARMRLMGNVTRAIVR-- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=A0A235E0M0_9SPHI -htELKKQIDEILNSYDAKAGIAIHNHDFSDSL-SINGNHKYPLQSTYKFHLGIAILDQVD -KGKLSLDQPVVFSKEMMNTYSPIKDKFPNGVLPLSEVMRYTIAESDNLGCDAMFELLAGP -DKVQEYFVKKGYTEQSIKTNEAVQQADWDIQFQNWTKVSQANKILFDYYTKNLLSESSHK -FLWDTMRSTSTGKNRIKGLLPKGTTVAHKTGYSGTAAVNDIGVISLPNGQVLYISVYVTD -SKETEPQSASIVAKVSKAAFDYf ->[subseq from] serine hydrolase n=1 Tax=Cyanothece sp. BG0011 TaxID=2082950 RepID=UPI000D1EC3F9 ---ALKEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQPIPAASTIKIPVLVAFFQEVD -KGNIHLDQMLTMTKDVMVSGSGDMQYMQENKFPAIEVARKMIVISDNTATEMLVKQIGGK -EVLNQRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLISIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYD-DIAGRHLIQEISRTVYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 67-41 TaxID=1895850 RepID=A0A1Q4E3T8_9SPHN ---ALDQAIRGITNNFEGLVGVAVTSIDDGWIV-ASNGERPMPQQSVSKLWVAMTVLDQVD -QGRIRLEDPITITRADFTLHQPVAALVKGDAASVGEIIRRAMQMSDNTCNDKLLRLVGGP -DAVRTFLARKGITGVRFGPGEKLLQASYVKDPPDGAAAAGISVALARLKRGELLSPTATA -WLLQTMDGAKTGRARVHGAVPPGWTYGHKTGTGQTAGFNDVGILTAPDGKSYALAIMIGD -THRPVRERQMLMQQVAQAIVT-- ->[subseq from] serine hydrolase n=1 Tax=Raoultella sp. 18102 TaxID=2681434 RepID=UPI00135CB146 ---ALKSSLERIASDAPGTLGIVVMDPASGTSV-KVNDGRPYLMMSAFKAPIAAAVLARVD -SGELKLDRTVHLVPADIVPGSPSLGKRLEAGVSVEELLRAAVTQSDNTAVDALLRLLGGG -AAATRFLESKGVHGMRIDFGERELSLQVLASHVNSTTLDGAAAFLEKLQAGALVSPSSTN -MLLGMMTAQVI-PNRVRAGLPAGFQLADKTGTAGLGAWNDMGIVTAPDGRRMIVAVFLSD -SPAAPKQADAWFAEIGRLVAA-- ->[subseq from] Uncharacterized protein n=1 Tax=Thermoprotei archaeon TaxID=2250277 RepID=A0A662UEV6_9CREN --eRLESELVNLVKSFPAKVGVGFKDLKTGAEY-YINGRERFLTASVFKVFVLIELYNQVV -KGELDLRRRYRISEKVKVLGSGILKELDEGLPTLRDLAKLMMILSDNIATDIIMELL-GK -DRINRTVRELGLRETRVYLTTGEILLETDLEYNNVTTPEEMVRTLELLYRGEVLTPEACR -EILEIMKACQTGEARIKRYLPYNVKVAHKTGTMP-GVVNDAGIVFTEKGD-YVLVVFING -LNQYVPLGEELIAQISKKVYDVy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644UT93_9ZZZZ ---ELKKEIEIIVGGKDLKLGFALYDFSTGKSI-SINGNDKYPMQSVFKFPIGVALLDCVS -RGEFSLSDSVTLTKADLLPWSPIRERWPEGVLPLVSVMTYMVAHSDNNATDFLIHKIGGV -ARIQDIVNRLGAKKINIRNTEAEIQGSWSVQFDNWTTPNAMVDFLRLMNDGKLLDKANTA -VLWEIMASASS--GSVNRLVPKTVAFARKTGYSGANAQNDVGIIEFEDGRRVAYAIFLTD -STLGTDAGYDILAQIGKSIWKAy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingomonas dokdonensis TaxID=344880 RepID=A0A245ZDE9_9SPHN ---AMTASITQLVREFPGIAGVAVRAVDEGWTV-EAGGRRPLPQQSVSKLWVAMTVLDQRD -SGRLRLDDAVSLTPADLTLHQPSAVLVKNGVTTVSDLLFRALTQSDNTANDRLLTLVGGP -QAVRSFIERKQLGDIRFGPGERLLQARYIDNPPDGAAPLAIADALSRLARGELLSETSTR -LLISTMESSRTGRARLKAGISPGWTLAHKTGTGQNAGFNDVGLLTSPDGRRYAVAVMIGD -TERPMRERQQLIQAVAATVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YR768 TaxID=1884365 RepID=A0A1H9U6V5_9SPHN ------NVVRNLGQSFRGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLADTTTITRNDLTLHQPTAALVAQNGSSYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKQNEMLSSASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVSIPERWALMQGVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=A0A0Q4J864_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGHRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. PAMC26645 TaxID=2565555 RepID=A0A4P7R2U8_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPILVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILIDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium amiense TaxID=135719 RepID=A0A494VWD1_9SPHN ------DVVRNLGQSFNGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRITDTATITRNDLTLHQPSAMMLKDGMTSYSDLLHRAMTQSDNTANDTLLRAVGGP -EAVRGYLARKTIRDIRFGPGERLLQSRYLANPPDGAAPSSIVQALARLKQNRMLSPASSR -LLMSIMSEAKTGPRRIKGGVPPGWTYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTRPIPERMELMQAVSRAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI000376D121 ---SLKSAIQNLAIQNNLTPGVFVADLDNGGYV-DFNGGAMFSSASTIKLAILIAFFQEVD -EGKINLEETLRTSKSTVAGGSGDMQNRPGTEYGILEVATKMMTISDNTATNMLIERMGGI -EKLNQRFRSWGLNTTSLGNILPDIEGT------NKTSPKELSNLMAMITKGNIVSSQSRE -RIIDIMQRTVK-DTLLPPGLGQGAKIAHKTGEIG-GILADTGLVELPSGKRYLISVMVQR -PRND-VSAEKLINGISRAAYQQf ->[subseq from] serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI0008477952 ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR -VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Rippkaea orientalis TaxID=2546366 RepID=UPI00017E6BD0 ----LKAKLDKIATQSKLKPQAWFMDLDNGAYV-SVNGSVPVPAASTIKIPVLVAFFEALD -AGKIHLDEILTMDKAIITSGAGNMQYPPGTKFTALETATQMIVISDNTATDMLIRRLGGK -EALNARFRDWGMTNTVINNRLPDLEGT------NTTTPEDLSKLLARIERGEVLTLRSRD -RLLGIMQETRT-RTLLPQGLEKDAIISHKTGDIGS-IIGDAGIIDIPNGKRYIGAVFTSR -PYND-PMGRALIQDFSRTTYQHf ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Bathyarchaeota TaxID=1700837 RepID=A0A1F5DFS1_9ARCH ----LLEAVKKPAEGFKGVLGVSVNHLGTGESA-SLNGDRLFPTASVFKVPVIVEFYRQVE -RGVLSLDERVTLREVDKVPGSGILRELTEGLVSLRDLLSLMMIVSDNTATDLVAGRV-GF -DNVNRTLRGLGLTRTSISRYCREILFSLGTENNDVTTPNEMNRLIALVSEGKAASQESCD -QILGIMAKCQTGPARIPKYLPREVRLERKTGSLP-GIRNDVGIVTLRTGERYALSCFTMG -AE-DVYSAEEVIAQVSLNVYTHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127STE2_9BACT ---PLAQQLKSIIENKKATVGIAVLY--NGKILvTVNDKAGYPMMSTFKFPLALAVLERLD -KQGLPLETELFISKPDLHPYGPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLENTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQI-------- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=UPI00141BD1D9 --rALDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas rubra TaxID=634430 RepID=A0A1I5R777_9SPHN ---QLQATVSQLLGNFGGKAGAAVRAVDEGWTV-EAGGRQRLPQQSVSKLWVAMTLLDLRD -QGRARLDEPITVLPADLTLHQPIAYLVAKSGTTVGGLLTRALTQSDNTANDRLLTYVGGP -EAVRRMILAKRLGDIRFGPGERALQARYTADPPDGAAPLAIADALARLARGELLSETSTR -ILLDTMGASVTGRARLRAALPVGWKISHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD -TTRPIRERQQLIQAVAAAVAA-- ->[subseq from] Beta-lactamase (Fragment) n=5 Tax=Bacteria TaxID=2 RepID=C5IDC8_9BURK ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDE---------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=A0A0S3F3F1_9SPHN ----LVSVIRNLGQSFNGHVGIAVRRVGADWTV-AFNGNQLFPQQSVSKLWVSMAFLDAVD -RGKLRLSDTTTITRKDLTLHQPSAAMVGNTGTTYSNLMNRAMTQSDNTCNDALLRAVGGP -DAVRGFLARRFISNIRFGPGERLLQSNYLANPPDGAAPASVVQALAKLKQGDMLSPSSTS -ALLSIMGEAKTGPQRIKGGVPPGWHYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc flagelliforme CCNUN1 TaxID=2038116 RepID=A0A2K8T0D0_9NOSO ------SQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMTISDNTATNLILDRLGGA -AKVSQRFRSWGLQNTALRNLLPDIAGT------NTTSSKDLVRLAALVYNNRLLSPNSRN -QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNHD-PKAGDFVRELSRRVYNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. PP-CE-3G-477 TaxID=2135660 RepID=A0A2T5GYB0_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPILVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIERKRLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium 13_2_20CM_57_17 TaxID=1803464 RepID=A0A1Q6YEY4_9BACT --qKLEATINGVDRNLDGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAILAELYRQAQ -QGKIKLGVLYTLQSSDLVGGSGIAGALTPGVLTIRDVAALMISVSDNSATNIIIDRV-GM -ENVNMLLDSLGLTRTRLRRKMMDVKAA-AEGRENIATPREMVQLLEDLYRGKVLNKQMTE -DFFALLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNR-PFVISVMTTY -LRRE-KDGGDAIVRIATAAYQMf ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An322 TaxID=1965632 RepID=A0A1Y4ANI5_9BACE --pALREQIQHIIGNAEAEIGVAVI-INGKDTL-TFNNEAHYPLMSVMKYHQALAVAHYLD -QRDLPLSTHIRIEKQDLRPYSPLRDKYPNGGLSIGELLTYTLQLSDNNACDILFEYIGGT -ASANQYLQTLGIEGFSISATENDMHQNPERCYENWSTPLSAARFMDSLIAGTLIDTAYTH -FIQETLLSCQTGKTRLPSPLQTDARIGHKTGTSDQNGINDVGFILLPDGKRYTVAVLVKH -SKLSYEETERIIADISTLIYQAy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T6T2_9BACT ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGD----------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. CAP-1 TaxID=2676077 RepID=UPI0012BB2A5C -------VVRNLGQSFNGKVGIAVRRIGSDWTV-AWNGNALFPQQSVSKLWVAMTFLDAVD -RGKLRITDSATITRSDLTLHQPSAALLKDGMTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGFLARRMIRDIRFGPGERLLQSNYLASPPDGAAPASIVQALSKLKRNEMLSSASSQ -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVGIPERWALMQAVARAVAA-- ->[subseq from] class A beta-lactamase n=1 Tax=Luteibacter anthropi TaxID=564369 RepID=UPI00141EB454 ---NLRASLEQVANQAPGTMGILVMDPASHETI-KINDGRSYLMMSVFKAPVAATVLDQID -HGKLSFDQKVHLTPADVVGGSPSLGVRLKSGVTIDELLHAAVTQSDNTAVDALIRVLGGG -KTVTTYLESKGVRGMRIDMGERELGAAVLASKVNSTTLDGAGSFLDHLQAGQLLPPAFTK -RLLDMMTAQVI-PNRIRAGLPQGFQLADKTGTALIGAWNDIGVITGPDGRKKIVAVFLSD -SPADRKQADAWFAEVGRLVA--- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc commune NIES-4072 TaxID=2005467 RepID=A0A2R5FQB2_NOSCO ------SQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMTISDNTATNLILDRLGGA -AKVSQRFRSWGLQNTALRNLLPDIAGT------NTTSSKDLVRLAALVYNNRLLSPNSRN -QVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Sulfotelmatobacter kueseliae TaxID=2042962 RepID=A0A2U3K1Y3_9BACT --qKLEASIQQVDQHLDGVMGVAIEDLTTGDHS-FLHEDEVFAQASSIKITVLAGLYLQAE -QGKLKLTDLYTVQSSDLVPDSYIMNGLTPGVVTLRDLATMMVAVSDNSATNVLIDRV-GM -PNVNAMLDSLGLTHTRLRRKMMDLEAA-KQGRENISTPREMMTLLDAIYHGKVMNKDSTA -DFFKVLSTNKD--SWIPRDLPADLKIANKPGALE-AVRNDSGVVFVEGR-PYVISVMTAF -LG-NERDGEEAISKISLEAWRMf ->[subseq from] Beta-lactamase class A n=1 Tax=Nodularia spumigena UHCC 0039 TaxID=1914872 RepID=A0A2S0Q3P4_NODSP ------DAVQNLAIASNLRPGVFLVDLETGGYV-DVNSSATFSAASTIKVPILIAFFQDVD -AGKVRLDEMLRMEKEMVAGGSGNLQQQVGTQYSALELATQMSASSDNTATNMLIARLGGM -EALNQRFLRWGLSATAIRNPLPDLPGT------NTSSPRDLGNLLAMVNQGNLVSMRSRD -LILDIMRRTER-NHLLPSGLGAGARVYHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR -PNND-HLAEKLISAISGAAYQQf ->[subseq from] serine hydrolase n=1 Tax=Dolichospermum flosaquae TaxID=1166 RepID=UPI0014461044 ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -GGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Beta-lactamase PSE-1 n=1 Tax=Dolichospermum sp. UHCC 0315A TaxID=1914871 RepID=A0A5C0DVE5_9CYAN ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -GGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Anabaena sp. 90 TaxID=46234 RepID=K7VYG2_9NOST ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -GGKIRLDEMLTLQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:633 TaxID=1262744 RepID=R6FLJ6_9BACE --tTLQSRISDFLKNKKATVGVSVL-TERGDTL-LYNNNLRYPLLSVFKFHIAMAVLDKMD -HAGTPLDSILHISSSQLQKYSPLRDKYPNQDISLRDLLKYSVSLSDNNACDILIDYAGGI -SKVDSYIRKLGIKNFHLSETENTMHQDPEKAYNNWSYPSEATRLLFIADTKTLFANNYKE -FLTEIMLGTTTGTDKLKGLLPPCTQVGHKTGSSDRNADNDLGFVTLPCGVKYYIAIFVMN -SYETDQENASIIAFISRLIYDE- ->[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium TaxID=1926873 RepID=A0A4Q2XU83_9GAMM ---DLLNAVQALGTGFKGDVGISVRDIDEGWAV-AWEGDNPRPQQSVSKFWVAIAVMDAVD -RGRLSLNGAVTVTRSDLTLHQPIRALVGKHGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLSEKGIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTT -SLLTLMRSSKTGPLRLKSGLRTGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPARMRLMGDVTRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7HP39_9NOSO ---ELKSPINKLVSRYKLTPGIFFMDLETGDYI-SVNGNKAFPAASTIKYPILIALFQEVD -AGRIKLNETLVMQRKYVVGGSGNMQYMRTGSFSVLKTATMMMTISDNTATNMIIARLGGI -AKLNQRFQSWGLQSTALRRMLGDFNGT------NKTSAKDLVRLSALMINNQLLSDKSQS -QVLGIMYGCHN-RKLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTPSGKRYLAGIFVRR -PNND-LRARDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase class A n=1 Tax=Dendrosporobacter quercicolus TaxID=146817 RepID=A0A1G9U2T0_9FIRM ----LRQHIETIIDQSSASWGIVIHRPATGQKL-EINPVQAFPAASMIKVPIMVEIMRQTA -AGIISLDDSLAVTSQVRVGGAGVLTERPDLTMTVRELVTLMIIISDNTATNLLIDLA-GM -PAINAAITNLGLNSTSLKRRMMDFAAA-QAGEENTTSAADMAALFELIRAKACLPPVYCD -LMLDLLSRQQV-RDKLPFYLPEEFKLAHKTGTLP-GVEHDGGILFFPAG-PCVVTVLAGN -LAAN-YQGLQWIAQIGKVIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=A0A0Q4EG27_9SPHN -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVLIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium fuliginis (strain ATCC 27551) TaxID=336203 RepID=A0A292ZIH9_SPHSA ---DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-AFNAERMLPQQSVSKLWVAIAVMDAVD -RGKLSLSDPVTVKKSDLTVHQPIRSLVTKAGTTVGKLLELAMTRSANSCNDVLLWKVGGP -QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSARSTR -HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGHRYAVAVMIAS -TRLPIPARMRLMGNVTRAIVR-- ->[subseq from] Beta-lactamase n=1 Tax=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) TaxID=269084 RepID=A0A0H3K538_SYNP6 ----LQTQLAALIQQQALKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLAALMEAVQ -QGKVRLDEQLTMTQDLVASEAGAMQYPVGSKFTVLETAIEMIRISDNTATNLLIARLGGI -EAVNQRFAAWGLQTTRIRNLLPDLEGT------NSTTPKEMVELLAKVENGSLLDPRSRD -RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPSGKRYIAAMLVRR -PDND-LKANELIRQVSQRTYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8YDY8_9BACT --qKLAATVNEVDSKLDGVLAVAILDLTTGQKY-LLHADEVMPTASSIKIAILAELYRQAQ -QGGIKLTDFYTLQQSDLVGGSGITSVLTPGMLTLRDVAGLVISVSDNSATNVIIDRI-GM -ENVNALLDSLGLARTRLRRKMMDLKAA-SEGRENVATPREMMLLLENLYRGKVLNRQMTE -DFFNLLSVHKE--SYIPRNLPEDVKVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTTY -LRRE-RDGGEAITRISDAAYQMf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=UPI0012E17045 ---DLLNAVQALGASFKGEAGISVRDIDEGWVV-AWAGDSPRPQQSVSKFWVAIAVMDAVD -RGRLSLSDPVTVTRSDLTVHQPIRTLVGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLAEKEIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. IBVSS2 TaxID=1985172 RepID=A0A1Y2QPV4_9SPHN ---ALDQAIRGITNNFEGLVGVAVTSIDDGWIV-ASNGERPMPQQSVSKLWVAMTVLDQVD -QGRIRLEDPITITRADFTLHQPVAALVKGDAASVGEIIRRAMQMSDNTCNDKLLRLVGGP -DAVRTFLARKGITGVRFGPGEKLLQASYVKDPPDGAAAAGISVALARLKRGELLSPTATA -WLLQTMDGARTGRARVHGAVPPGWTYGHKTGTGQTAGFNDVGILTAPDGKSYALAIMIGD -THRPVRERQMLMQQVAQAIVT-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. Leaf257 TaxID=1736309 RepID=A0A0Q4UAK5_9SPHN ------------------------------------------------------------- ---------------------------------TAAKAMEAMIVRSDNLAADQMFATLGGP -AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPVAMVQLLRILDSGTALSSQSRA -YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVSRMIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6ST02_9SPHN ------AVVRNLGQSFSGKVGIAVRRIGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPSAMMLKDGMTSYSDLLRRAMTQSDNTANDALLRAVGGP -EAVRSYLARKAIRDVRFGPGERLLQSAYLANPPDGAAPSSIVQALARLKQNRMLSPASSR -LLMSIMSEAKTGPRRIKGGVPPGWTYLHKTGTGQSTGYNDIGIMTAPDGTSYAIAVMIGS -TTQPIPARMELMQAVSRAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. UWO310 TaxID=2480795 RepID=A0A6C2E1Q5_9CYAN ---ALLAKIKELAKEKDLSMQMMMVDLDSGTYV-QIGANQPIAAASTIKTPILVAFFQDVD -AGKIKLDEPLEMTADVKVGQAGDLQYLPTGTISALETATKMIVISDNTATNMIIKRLGGA -VALNQRFKSWGLNSIVINNQLPDLEGT------NTISTQDLATLLSMLDRGKLIEPRSRD -RFMDIMRRPVT-NTLLPQGLGEDARIIHKTGDIAS-SVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRATYEYf ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter odishensis TaxID=1155476 RepID=UPI000E716842 --eELSDKLEAIGEEFGGTLGIAVVDVDTGWST-GFNETALLPQQSVSKTWVTLTALTMAE -KGLLNLDAPIRVSREDLTLHQPIRKEILRSGTTVGELIERAIQQSDNTANNAILQRVGGP -RAVRAMLREQGLDGIRFGPGEKPMQANYLADPVDGARPIAIARALAAIERGEVLSPKRAE -EFLTIMSNTRSGPRRLKGGRAEGWVVSHKTGTGQQSGYNDVGVLFAPDSSAYAVAVMIGV -TKRPTIERMQMMQEVTRAVIA-- ->[subseq from] Beta-lactamase n=2 Tax=Parabacteroides goldsteinii TaxID=328812 RepID=A0A0J6CBE0_9BACT ------DRIEKIIHGKKASVGVAILY--KDKMF-LISNGNKYPLMSVFKFHVAVAALKEME -YKGIALDSTVCIKAEQMHKYSPLRERYPDQDISYGSLIEYTASLSDNNTCDILIDFVGGI -SKVEAYIHTLGISDIQLTETEYTMHQNLDNCYRNWSTPQSVVALLKKVYTENVLSQEHFL -FLEQAMLSTPTGKNKLRAGLPECIALAHKTGQSGRTGDNDAGIVYLPSGEKCYIAVLIKD -SKETDAENASIIADIAKEVYN-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=A0A0Q4G0G7_9SPHN ---DLLNAVQALGASFKGDAGISVRDIDEGWVV-AWEGDSPRPQQSVSKFWVAIAVMDAVD -RGRMSLSDPVTVTKSDLTVHQPIRTLVGADGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -DAINRMLAEKGVAGVRFGPGERQLQARYLAAPLDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A349PDT0_9BACT --------IEKTSGAYRGRVGIYLKDIQTGRVW-EYNAAGLFPSASLIKVPIMAAVFEKIK -LGAITLDTQIRLTNRGRVGGSGSLKWVREGTLSVMEIIYKMITESDNTATKMLIDYV-GM -PYLENSFRKLGLVQTNITPEGMSLASG-RVKNENYTTAREMAGLMERIYEGELVNREASE -FMLDVLKHTKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-FVLAVLTSE -VP-DYTSAKNFITRVAKLTYAYy ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:755 TaxID=1262935 RepID=R5GFE1_9BACT ---SLRNEMSRVTAGLHATVGVSFIH--NGRLF-TFNDSVHYPMMSVYKVPVALAVLQKMS -STGTSPATRIEVKREQWHPYSPMREAFRDSSIRLADLLHYCVAMSDNNAADILTAYVGGI -TVVARTVESLIGKKMHISETEQDMHENTENVYNNWCHPSAMAILLQEIYEGNALDSSARA -YFERLMRSTQTGTDKMPAGLPPGIALGHKTGSSDKAGDNDAGVIYMPDGKRCYAAVFIKD -STESDATNAQTIATLTRLIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11372 TaxID=2055768 RepID=A0A350XJ15_9CYAN ------AEITALEQYPKLTPGIFILDPDTDGYF-DLNGTSAIASASTIKIPILVAFFQDVD -AGKIRPDELLTMKPQFIATGSGNMQKFPGSKYTALETATKMITISDNTATNMLIERLGGA -EALNQRFASWGLTATAIRNQLPDVEGT------NTTSAKDLANLIAFVNQGELVSRQSRL -SLLSIMRRTER-NHLLPRGLGQGATIAHKTGYIG-AMLADAGLIELPNGKRYIAAVMVKR -PQND-PRAEKLIRQISRIAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera malacea cyanobiont' DB3992 TaxID=1206980 RepID=A0A2D0HFP3_9NOSO -----TSQIRTLLASYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLSDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA -AKVSQRFRSWGLQNTAMQNLLPDIGGT------NTTSSKDLVRLAALVSNNRLLSPASRN -QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-RRAGDFVREVSRRVYNY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Myroides sp. N17-2 TaxID=2030799 RepID=UPI000EFB1A8A --qKLKQQIEPILQHKKATVGIAIIY-DGKDTL-TFNNDHKYPTMSVYKFFQALTILDYMD -KHNIDLNTPMFIKKEDLKEYSPLRDKRPMGDMPIGELIQYTASHSDNNISNLFFSSLIGP -KMTDLYYRSIGIKEFEIVSSEEEMSLDFNNQYDNWITPLEATRILELFHRKELLSPKYKA -FLQQAMIDTKSGQDKVKALLPKNTVVVHKTGMSFRAVDNDLALVYLPNGKQFSIAVFVMD -SLEDDKTNASIIAQVAKVAYDYy ->[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. 'Lobaria pulmonaria (5183) cyanobiont' TaxID=1618022 RepID=A0A2L2NK45_9NOSO -----TSQIRSLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA -AKVSQRFRSWGLQNTALRNLLPDIAGT------NTTSSKDLVRLAALVSNNRLLSPTSRN -QVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Serratia TaxID=613 RepID=U6A4G9_SERFO ---------------------------------------------------AVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPVAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. TaxID=47254 RepID=A0A2W7AQA1_9CYAN ----LQQRLASLRSGASLKPGMFFMDLETGNYA-EVNGDKVYPTASIIKLPILIALFQEVD -AGNIRLNETLTMTRDVIVGGSGEIQDLPPGTFSLLETATKMIVISDNTATNMIIKRMGGI -QVLNARFRSWGLQKTAMRNMLPDLKGT------NTTTARELVRLLAMLDKQQLLSSQSQG -QVLNILQRVRN-RTLLPVGLARGATIAHKTGDIGF-ILGDAGIIQMPTGKRYLAAVLVES -AY-DDPSARDFIQDVSRIVYTY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 43529 TaxID=1840705 RepID=A0A367PW02_9NOSO -----SSQIRTLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQDID -AGKIKLTDKLVMRRDLRVGEAGTMQKPIGTKFSVLETATLMMTISDNTATNMVLDRLGGA -AKVSQRFRSWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVYNNRLLSPNSRD -RVLGIMRGVKT-NSLLPAGIGKGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNHD-PKAGDFVREVSRRVYNY- ->[subseq from] UPI0014399A39 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0014399A39 ----LQSRVDALVRSFPGKAGAAIVAVDEGWSV-ERGGSLSLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVTRDDLTLHQPIAGLVRGEGTTVGALMTRALTQSDNTANDRLLTFVGGP -SAVRAFISEKRLGAIRFGPGERLLQSRYVDNPPDGAAPLAIADALARLARGELLSETSTR -LLLETMTASRTGHARLRAATPAGWELAHKTGTGQNAGFNDVGLVTAPDGRRYAVAVMIGD -TTAPIRDRQRLIQNVASSL---- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter oceanensis TaxID=1463597 RepID=UPI001369BBB0 ---SLERRVAMVADGDRGRIGVYAIDLTTGREV-GILADQRFPMASTSKVAIAAAYLAGVD -KGRWTLSSEWRLPRA------------GGTYMPAHQHLKLMIAKSCNDCTDALLEAVGGP -AAVNRWMKEAGIEDFQLNRYISSLVRASSIDLKDSATPRAMGQLLAGIYQGKWLSASSRR -VLLDAMEQTTTGKKRMPAALPMSANLAHKTGTLSR-TASDIGIFYTPDGRAIAAAIYVTG -QSPSMAAEN-------------- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc calcicola FACHB-389 TaxID=1357508 RepID=A0A1U7HXG5_9NOSO ------SQIRTLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLRVGESGTMQKPVGTKFSVLETATLMMTISDNTATNMVLDRLGGA -AKVSQRFRSWGLQNTALRNLLPDVAGT------NTTSSKDLVRLAALVSNNRLLSPNSRN -QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=A0A0Q4K649_9SPHN ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. KY5 TaxID=2011159 RepID=A0A2Z4K1L3_9SPHN ---AFEQKLEEIGASLSGTVGIAVEDVDTGELY-EFNGDEMLPQQSVTKLWVAMAALSQVD -QGDLKLTERVRIGRDDLTLHQPIREIVKARGTNYRDLFERSITRSDNTANDRLLRRVGGP -EVVQKWLSDNQLDGIRFGTDERSKQSGYLADPIDGASANAIASALAKLARGDLLGENTTM -LLRNTLEQTRSGPRRLKGGAPDGWRVEHKTGTGQQSGYNDVGILTSPDGREYAVAVLIGR -TSEPTPVRMDMMQQVTIAIAE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=UPI000D3D1A48 ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. STIS6.2 TaxID=1379700 RepID=UPI000D13F7E5 ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] Serine hydrolase n=3 Tax=unclassified Sphingomonas TaxID=196159 RepID=A0A0Q4I602_9SPHN ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. T1 TaxID=2653172 RepID=UPI001358A6EE ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] serine hydrolase n=1 Tax=unicellular cyanobacterium SU3 TaxID=1982589 RepID=UPI000B3E1A08 ---ALKEKIQKIDAKYNVKPQAWFIDLDNGAYV-TYNGTQAVPAASTIKIPVLVAFFQEVD -AGNMHLDQMLTMTKDVMVSGSGDMQYMQENKFPAIEVARKMIVISDNTATEMLVKQIGGK -EVLNQRFKEWGMKHTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLIAIMEGTKT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYD-DIAGRHLIQDISRTVYQHf ->[subseq from] Serine hydrolase n=1 Tax=Nodularia spumigena CENA596 TaxID=1819295 RepID=A0A166I2Q2_NODSP ------DAVQNLAIASNLRPGVFLVDLETGGYV-DVNSSATFSAASTIKVPILIAFFQDVD -AGKVRLDEMLRMEKEMVAGGSGNLQQQVGTQYSALELATQMSASSDNTATNMLIARLGGM -EALNQRFLRWGLSATAIRNPLPDLPGT------NTSSPRDLGSLLAMVNQGNLVSMRSRD -LILDIMRRTER-NHLLPSGLGAGARVYHKTGDIAT-MLGDVGLIDIPTGKRYIAAVMVQR -PNND-PLSEKLISAISGAAYQQf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia fonticola TaxID=47917 RepID=U6A4I8_SERFO ---------------------------------------------------AVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALAEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A1C5V3Z5_9BACE ---SLRNEIIHSICKYDAKVGVAVM-VNNTDTL-TVNNSDKYPMMSVFKFHQALAVCHFLQ -MKGIPLDSVINISKEELREYSPLRDRFPEGNISLLELMEYTLQLSDNNACDILFNRILSI -KETDRYIRSLGIDDFSIEMDENDMHENLDNCYSNWTTPMAAVRLINLFLEGDAVSGEYYD -FIKRTMTECTTGTGRLPYPLKTAAVIGHKTGTGDKNGINDIGFIDLPNGDRYLIAVFVKD -SAENYETTEKIIAEISSIVYK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas aerolata TaxID=185951 RepID=A0A2T4YVX7_9SPHN ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus elongatus PCC 11801 TaxID=2219813 RepID=A0A3G6X3A5_SYNEL ----LQTQLAALIQQQTLKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLTALMEAVQ -EGKVQLDEQLTMTKELVASEAGAMQYPVGSKFTVLESAIEMIRISDNTATNLLIARLGGI -EAVNQRFAAWGLETTRLRNLLPDLEGT------NSTTPKEMVELLAKIENGSLLKPRSRD -RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPNGKRYIAAMLVRR -PDND-LKANELIRQVSQRTYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia z16 TaxID=1628751 RepID=A0A2C6W0A7_NOSLI ---ELKTPINKLVSRYKLTPGIFFMDLETGDYI-SVNGNKAFAAASTIKYPILIALFQEVD -AGRINLNETLVMQRKYVVGGSGSMQKRVGSKFSVLKTATMMMTISDNTATNMIIARLGGI -PKLNQRFRSWGLQSTALHRMLGDFNGT------NKTSAKDLVKLSALMVSNQLLSDKSKS -QVLGIMYGCHN-RKLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIQTPSGKRYLAGIFVKR -PNND-LRARDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase n=1 Tax=Crocosphaera watsonii WH 8502 TaxID=423474 RepID=T2I6S8_CROWT ----LQEKIQKIDAKYNVKPQAWFIDLDNGSYV-TYNGTQPVPAASTIKIPVLVAFFEEVD -KGNIHLDQMLTMTKDIMVSGSGDMQYGINKKFTALEVARKMIVISDNTATEMLVKQMGGK -EVLNKRFKKWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-VAGRHLIQDISRTVYQHf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9N8D3_9BACT --qKLQVSIAGTDRELDGILGVSIQDLSSGEQF-SLHGDEVFPQASSIKIAVLAELYRQAA -QGKLKLTDLYTVNSADLVADSYIMNGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GI -ENVNALLDSLNLPHTRLRRKMMDIKAA-AEGRENISTPNEMAGLLRAVYQKKFFDAALTE -DLFKVLSTPK--DSWIPRELPDDLKIANKPGSLE-GVRNDSGIIFLANR-PYILCVMTTY -LRR-ERDGEQAISRISLAAWRMf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. T1 TaxID=2653172 RepID=A0A654B731_9SPHN ------TAIDALHHDFAGKAGIAIRAVDEGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGKAKLEDPVVVRAEDLTLHQPIAMLVTGDGTTVGELLRRALTHSDNTANDRLLSYVGGP -RAVRGMILRKQLGEIRFGPGERLLQSAYVANPPDGAAPIAIADALARLARGELLSASSTQ -VLLDTMGASVTGRARLRAALPAGWRIAHKTGTGQNAGFNDVGLLTAPDGKRYAIAVMIGD -TLRPIRERQMLIQAVAAAVAA-- ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 6303 TaxID=1170562 RepID=K9V5T9_9CYAN ----LKSAITNLTTTTNFTTGVFLVDLDTNSFV-DINGARTFSSASTIKLPILIALFQEVD -AGKIRLEDSIATKQELLAGGSGDIQQPIGTKYTILDLATKMITISDNTATNMLIERLGGI -ENLNQRFRGWGLASTSLRNLLPDLKGT------NTTSPKDLAGLIAMITKGNIVTNQSRD -RILDIMRRTVK-DTLLPSGIDQGATIAHKTGDIAS-MVADVGLIESATGKRYIAGVMVER -PNND-NRAETLISSISRLTFQ-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A2V8XDJ7_9BACT --qKLATTVNEVDRNLDGVLAVAILDLSTEQKY-LLHADEVMPTASSIKIAILAELYRQAQ -QGKLKLTDFYTLQSSDLVGGSGISSVLTPGALTLRDVAGLMISVSDNSATNVIIDRV-GM -ENVNALLDSLGLTHTRLRRKMMDLKAAG-EGRENIATPREMMLLLESLYRGKVLNKQMTE -DFFNLLSVHKE--SYIPRELPEDLKVANKPGELE-GVRNDSGIVFTGKR-PYVISVMTTY -LRRE-RDGGEAIIKISNAAYQMf ->[subseq from] Beta-lactamase enzyme family protein n=2 Tax=Lyngbya aestuarii TaxID=118322 RepID=U7QP35_9CYAN ----VKQQILALTENSDLKPGVLLVDLDTGGYV-DINSESAFAAASTIKVPILVAFFQAVD -EGKISLNEVLTMEDQHIAGGSGDMQYQSAGTYTALETATKMIVISDNTATNMLIERLGGA -EFINQKFLDWGLHNTVIRDVLPDLRGT------NKTTPKDLVNLLTQLNQGGLVSMKSRD -RIFRIMEKTEN-DSLLASGLGRGAIIAHKTGNLKS-VSGDVGLIDLPNGKRYLLAVLVER -ND-DDSAAESLIRNISKTVYESf ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides ndongoniae TaxID=1903262 RepID=UPI000DE5A566 --tTLQSRISDFLKNKKATVGVSVL-TERGDTL-LYNNNLRYPLLSVFKFHIALAVLDKMD -HAGTPLDSILHISSSQLQKYSPLRDKYPNQDISLRDLLKYSVSLSDNNACDILIDYAGGI -SKVDSYIRKLGIKNFHLSETENTMHQDPEKAYNNWSYPSEATRLLFIADTKTLFANNYKE -FLTEIMLGTTTGTDKLKGLLPPCTQVGHKTGSSDRNADNDLGFVTLPCGVKYYIAIFVMN -SYETDQENASIIAFISRLIYDE- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Sulfotelmatobacter kueseliae TaxID=2042962 RepID=UPI000D109E6D --qKLEASIQQVDQHLDGVMGVAIEDLTTGDHS-FLHEDEVFAQASSIKITVLAGLYLQAE -QGKLKLTDLYTVQSSDLVPDSYIMNGLTPGVVTLRDLATMMVAVSDNSATNVLIDRV-GM -PNVNAMLDSLGLTHTRLRRKMMDLEAA-KQGRENISTPREMMTLLDAIYHGKVMNKDSTA -DFFKVLSTNKD--SWIPRDLPADLKIANKPGALE-AVRNDSGVVFVEGR-PYVISVMTAF -LG-NERDGEEAISKISLEAWRMf ->[subseq from] serine hydrolase n=1 Tax=Synechococcus elongatus TaxID=32046 RepID=UPI000F7F5C3B ----LQTQLAALIQQQALKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLAALMEAVQ -QGKVRLDEQLTMTQELVASEAGAMQYPVGSKFTVLETAIEMIRISDNTATNLLIARLGGI -EAVNQRFAAWGLQTTRIRNLLPDLEGT------NSTTPKEMVELLAKVENGSLLDPRSRD -RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPSGKRYIAAMLVRR -PDND-LKANELIRQVSQRTYQ-- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014479C54 ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -EGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc linckia NIES-25 TaxID=1091006 RepID=A0A1Z4LE45_NOSLI ----LSSQIRSLLASYSLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQDID -AGKIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA -AKVSQRFRSWGLQNTAVRNLLPDVAGT------NTTSSKDLVRLAALVSNNRLLSPNSRD -RVLDIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XQN4_9CHLR ---TVASEIERLADATGGIVGLAATQLATGRHI-GHREDELFPTASVIKLPLLVTLYEDAI -AGRIDLSERVVYREGTKVAGSGVLQYLDDGLPTLRDLSVLMMSVSDNTATDLLFDRV-GK -TRIEATMDRLGLSSTRVPFDIRAMLMSMIPDQADRTTPADMSRLLELIESRSILDADACT -AIIELMKRSQS-GTRIPGLLPKGTVVAHKTGSYRR-LRNDVGIVYAPNG-PYVIALFARE -LARDNVDDDGALARISLAVYEEf ->[subseq from] serine hydrolase n=1 Tax=Thermoanaerobacterium saccharolyticum TaxID=28896 RepID=UPI0005F01027 ---SLHDDIMNFVSNAGGDIGVSVKNLKTGERI-DINEDMMFPSASTIKILIMAQIYKMAK -EGYIRLTDNIVLSDFMKTDGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINRMAEDLGLVHTKIQRKMMDFEAA-KSGKDNYTCPKDMAHLLEQMYAGKVVDEEHSI -KMIEVLKKQQD-LGRLDMYLPDDVVIAHKPGELKH-LEHDVGIVFLKDCD-YIISVMTNN -LSTN-LDGRRAIGKISKMVYDEy ->[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. BC1403 TaxID=2043171 RepID=UPI000CD8D601 ---------KDLAKEKDLSMQMMVVDLDSGAYA-QIGANQPIAAASTIKAPILVAFFQDVD -AGKIKLDEQLEITADVKVGEAGDFQFLPTGTISALEVATQMIVISDNTATNMIIKRLGGF -SALNQRFKSWGLNNVVVNNQLPDLEGT------NTISTQDMVSLLAMLDKGKLIEPRSRD -RFMDIMRRPIT-NTLLPKGIGEEARIIHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQVSRATYDYf ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001445AD64 ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -EGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf208 TaxID=1735679 RepID=A0A0Q4EXB0_9SPHN ---DLLNAVQALGASFKGEAGISVRDIDEGWVV-AWAGDSPRPQQSVSKFWVAIAVMDAVD -RGRLSLSDPVTVTRSDLTVHQPIRTLVGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLAEKEIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. 67-36 TaxID=1895849 RepID=A0A1M3DAN0_9SPHN ---ALVEQVDALVRGFPGVAGIAIRAVDDGWTV-ESGGRRRMPQQSVSKLWVAMTVLDQRD -SGRLKLDDPVTLYPSDLTLHQPIAALVKPSGTTVGALLTRALTHSDNTANDRLLTLVGGP -AAVRSFIERKQLGDIRFGPGERLLQSAYIADPPDGAAPLAIADALARLARGELLSETSTR -FLLTTMGSTVTGRARLKAALPPGWSLEHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TMRPMRDRQLLIQAAAGAL---- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas carotinifaciens TaxID=1166323 RepID=UPI000DD8B938 ------RTVQTLYAGFEGKKGIAIRAVDDGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -KGKARLDDPITVRREDLTLHQPIAYLVKGDGTTVGGLLTRALTQSDNTANDRLLTYVGGP -AAVRRMIAEKRLGDIRFGPGERLLQAAYVADPPDGAAPIAIADALARLTRGELLSETSTR -ILLETMGASRTGHARLRAAIPASWQLAHKTGTGQNAGFNDVGLLTAPDGRRFAVAVMIGD -TTEPIRNRQVLIQNVAAAVAT-- ->[subseq from] serine hydrolase n=1 Tax=Geminocystis herdmanii TaxID=669359 RepID=UPI0011819F2E ---DLKNKFAQLQTKYQLEAGAFFVDLDNGAFV-NFNGITTFSAASTIKTPILVAFFQDVD -AGKIYLDEQLATSPSNIGGGAGGMQQPVGTKYSAIHTATEMIVNSDNTATNMIIERLGGK -DELNRRFKEWGLDVTQISNLLPDLEGT------NTTSPRDLAMVLAKVNQGDLISVRSRD -RMLDIMRQTRT-RTLLPQGIEKDATIAHKTGDIGT-VLGDAGIIDIPTGKRYIGGVLVKR -PHND-YTARTLIQDISRTAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3WI38_BRECH -----EQVIQETLIDAPGVFGVAVTHLETGETA-GNLDDQLFQLASAFKIPILVTLMRDVE -EGKIRLDQRVPLKWNERVPGSGILQELDAGALTVKDLATLMTIVSDNYATDLILNLV-GL -KNVNTHMRELGLEEIHLRHTCWQLLNSMPTLDNNVATPADLNRLLVMIAKKEILTPASCD -IMLDIMRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPNKGAIAITVLSRG -IK-DKQAAELTIARVAKAIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E9V1C0_9SPHN --rKLDREISRIGGTFPGHVGIAVRDIAARRTL-HFNGLQLFPQQSVSKLWVTLTALGEVD -AGQLELTEKVEIRDPDLTVHQPIRDIVRRRGTDYADLIERAITHSDNTANDRILRRVGGP -DVVQKFLDDHGLSSIRFGTDERTKQSAYLADPIDGAPPVAIVEALARLXEGKLLSGPSTA -LLLATMSRTKSGPQRLKAGAPQDWIVRHKTGTGXQSGYNDIGLFTSPDGRTYAIAVMIAR -TRVSIPERMAMMQEVVRAVVNY- ->[subseq from] Class A beta-lactamase, subclass A2 n=4 Tax=Bacteroides TaxID=816 RepID=A0A642EKK6_BACFG ----LESKIKKSIENVPAQVGVAII-INGKDTI-TVNNECHYPLMSVMKYPQALAVLHYLH -QHNQPLFTKIFIPKEALLDYSPLRDKYPGGNMPIDQLLDYTIQKSDNNACDILFNYTGGV -SYTDSYIRSLGINNFSISKTEDDMHEDLAACYENWSTPLEIASLTDMLFSKELFPTEYQN -FLKETMLNCQTGTNRLPVLLDTTARIGHKTGTSDRNGINDVGFILLPDGKRYTIAVLVKD -SKESMADTEKIIANISGIVYHH- ->[subseq from] Beta-lactamase n=2 Tax=Pseudanabaena TaxID=1152 RepID=L8N0H5_9CYAN ---ALLAKIKELAKEKDLSMQMMMVDLDSGTYV-QIGANQPIAAASTIKTPILVAFFQDVD -AGKIKLDEPLEMTADVKVGQAGDLQYLPTGTISALETATKMIVISDNTATNMIIKRLGGS -VALNQRFKSWGLNSIVINNQLPDLEGT------NTISTQDLATLLSMLDRGKLIEPRSRD -RFMDIMRRPVT-NTLLPQGLGEDARIIHKTGDIAS-SVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRATYEYf ->[subseq from] Putative beta-lactamase n=2 Tax=Leptolyngbya boryana TaxID=1184 RepID=A0A1Z4JC10_LEPBY ----------AIAPQTQLTPGLMVVDADTGAYF-DINGSNAIPAASTIKFPILVAFFQAVD -EGKVRLDQPLTLKKEQIAAESGDLQDQPGSQFPAIQVATKMIDISDNTATNMIIDLLGGK -EAVNQRFQAWGLTNTVIQNALPDLQGT------NTSSPRDMVTLLSAVNSGKLVSMRSHE -RMLTIMRKVVN-NSLIPQGLGQGAVIAHKTGDIGM-MLGDVGMIDLPNGKRYFMAAMVKR -PHND-DRAGDAIRKMSELTYQYf ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WOR-1 bacterium RIFOXYC12_FULL_54_18 TaxID=1802584 RepID=A0A1F4T669_9BACT ---ELSQRFAALTRNHGQKVGVAFIDLKTGREL-TVNGTAEFPTASVGKVPVMAAAYALAD -KSQLNLDTKVRYLAEDRLGGSGLLQWTKCGRYSLRRLISLMITHSDNTATKMIVDNL-GL -AAINDYLRSQGLNDIVIADPT--MLREPPLPGRNLTTPLAMAHLVTRIEQRRGFSETSTA -EMLKFMRNQKY-RWGLWQGVPPGTTIADKTGNLT-GILNDVGIVYTKAGN-YVLAIFTQG -FSQK-NNARRLINQLSQAAYEEy ->[subseq from] Class A beta-lactamase n=1 Tax=Sandaracinaceae bacterium TaxID=2510337 RepID=A0A520PXB6_9DELT ---TLQGELAEIAARIDGRVAIAVVSLDRGGEW-AVNGDAPMPQQSTFKTWLAVAAADAVE -RGEASWEDEVRIERAHLLFYQPIAEEVGPEGFTLAHLVEQILLVSDNPSADAILRHLGGP -GAVQAALERRGVEGVRITTNEEGLHAAALAADPNAATALGAARSLARLARGELLSEASTR -RILSLMEASETGQARLRAGLAPGWALAHKTGSGFEVGANDIGVLTAPDGRRYAVAVFVAG -TTADAATRDGVIAGVARAVTR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZMS0_9BACT -----RAHIETLIARSGADVGLAFRTLDGRDEL-LIQPDVEFHAASTMKVPVMIELFRKAR -AGALKLDDRIPVANESIVDGSPYKYKHVGGTMSYRDLCEAMITVSSNFATNLLIERL-GA -KNVQRTTESLGAPGMHVLRGVEDDK-AFRQGLNNTTTARGLMTLMEKIAKGEAVDKPSSD -EMIAILERQHF-NDRIPAGLPEGTRVAHKTGEITK-IQHDAAIVFAE--RPYVLVILVRG -LQ-DARKGSALAADISRVIYE-- ->[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4S861_9BACT ---SLRPALEERIARHQGVVGLAIIDLATGDTL-SIRGDEPFPTASVIKVPVLVEVFHQVE -NGRLRLEDPIVMLDVDKRPGSGVLQYLTAPLITVRDAAFLMIALSDNTATNLLVDKV-GI -RAVTARMDSLGLPRTALHSKVFDRSSSVAPDSSGVTTPNEMARLFAMIHRGEAVSPEASR -EMLRMLRAQFY-TDAIPRYLPAGTTVAHKTGSID-AARHDCGIVSSREPRDYVLCVFTKE -NQRTDNEAHVLIADLARLVH--- ->[subseq from] Beta-lactamase n=2 Tax=Labilithrix luteola TaxID=1391654 RepID=A0A0K1PTJ4_9DELT -------------------------------------------MQSVFKLPLAIELLAHVD -AGDLRLDDEVTIRPSDLRPGGALADELPNGGRSMLALLERMVIASDNTAADILLERVGGP -RKVTDRLHALGIEGVDVSRSEADLHFTYLADPRDTAKPNAMVDLLLRVHQRKVLKPESGE -RLVSILERTTTGKKRLRGLLPPETVVAHKTGMSDTAATNDVGIITLPGNGHVVIAAFLSN -SKGDDDTRDRAIATVTRAMVDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium barthaii TaxID=1054037 RepID=A0A4R6FHP7_9SPHN -------VVRNLGQSFNGKVGIAVRRVGSDWTV-AWNGNLLFPQQSVSKLWVSMTFLDAVD -RGKIRLSDSTTITRKDLTLHQPSAALVGNSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRSYLARRYIKDIRFGPGERLLQSNYLASPPDGAAPSSIVHALAKLKENDMLSPASSQ -LLLSIMGEAKTGPQRIKGGVPAGWHYLHKTGTGQSTGFNDIGIMTAPDGTCYAVAVMIGS -TTEPIPVRWQLMQAVAKAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobium yanoikuyae ATCC 51230 TaxID=883163 RepID=K9CUT5_SPHYA ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSSGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSASAR -VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGFNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae subsp. rhinoscleromatis TaxID=39831 RepID=A0A378EHS6_KLEPR ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPRRRP--------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Staphylococcus hominis TaxID=1290 RepID=A0A533IUA6_STAHO --------IRSLVADFDGLVGVAVRSVQDGWTA-SANGDRLMPQQSVSKLWVAMTVLDTID -RGRATLDSPVSITWDDLTLHQPIAALVKRDRTTVRELLGRALTQSDNTANDRLLRFVGGP -AAVRAFIERNALGSIRFGPGERLLQSRYIADPPDGASASAIAHALSQLKRGRLLSPGSTA -YLISTMESSRTGKQRLRGAVPPGWRFGHKTGTGQTAGYNDVGLLTAPDGKSYAIAVMIGD -TGRPIPARQQLMQAVVATVVA-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. LK11 TaxID=1390395 RepID=A0A1P8PU94_9SPHN ------------------------------------------------------------- ---------------------------------TAAKAMEAMIVRSDNLAADQMFATLGGP -AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPVAMVQLLRILDSGTALSSQSRA -YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVSRMIYDRf ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FBA02 ------------------------------------------------------------- -------------------------EKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASLQ -QLIDWMEADKVAGPLLRSALPAGWFIAYKSGAGERGSLGIIAALGPDGKPSRIVVIYTT- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonadaceae TaxID=41297 RepID=A0A656PT59_9SPHN -----VSVIRSLGQSFKGKVGIAVRRIGADWTV-AWNGNSLFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTLTRNDLTLHQPSAALVAKQGTSYSDLMRRAMTQSDNTCNDALLRAAGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSAIVAALAKLKQGDMLSPASTR -LLLNVMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVPIPERWALMQAVSKAVAA-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A0A1WCM5_9SPHN ------------------------------------------------------------- ---------------------------------TAAKAMEAMIVRSDNLAADQMFATLGGP -AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPVAMVQLLRILDSGTALSSQSRA -YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVSRMIYDRf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf20 TaxID=1735685 RepID=UPI0012E1C109 ---DLLNAVQALGASFKGDAGISVRDIDEGWVV-AWEGDSPRPQQSVSKFWVAIAVMDAVD -RGRMSLSDPVTVTKSDLTVHQPIRTLVGADGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -DAINRMLAEKGVAGVRFGPGERQLQARYLAAPLDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pelosinus propionicus DSM 13327 TaxID=1123291 RepID=A0A1I4LZ33_9FIRM --kELQKKIEDTLAAYTGRWGMVIQNHSNGQHF-ALNPDMVFPAASMIKIPIMYEVMRQAA -AGKIDLEQLLIVKDELRVDGAGILKERPGIAMTIRELVTLMIILSDNTATNMIIDFI-GM -STVNQTMEHLGLKSTVLRRQMMDFAAA-AAGLENETSSADIICLLTKIYDHTNLPADYGK -LMIDILSRQQV-RDKLPFFLPEEIAIAHKTGTLP-GVEHDGGILFLPGG-PYIVCIMTAD -LPAN-VEGLQLVAALGKVIYEHf ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sphaeroides TaxID=446679 RepID=UPI000E46C73E -----TSQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLRVGEAGTMKKPIGTKFSVLQTATLMMTISDNTATNLILDRLGGA -AKVSQRFRSWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVYNNRLLSPNSRN -QVLGIMRRVKT-NTLLPAGIGKGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNHD-PKAGDFVREVSRRVYNY- ->[subseq from] Beta-lactamase n=1 Tax=Synechococcus elongatus (strain PCC 7942 / FACHB-805) TaxID=1140 RepID=Q31MT6_SYNE7 ----LQTQLAALIQQQALKAELFLTDLDTGNYV-DINGTTSIPAASTIKIPVLAALMEAVQ -QGKVRLDEQLTMTQDLVASEAGAMQYPVGSKFTVLETAIEMIRISDNTATNLLIARLGGI -EAVNQRFAAWGLQTTRIRNLLPDLEGT------NSTTPKEMVELLAKVENGSLLDPRSRD -RFFAVLRTTET-NTLLSRGLGEEATIAHKTGDIAM-VVGDVGLIDMPSGKRYIAAMLVRR -PDND-LKANELIRQVSQRTYQ-- ->[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:255 TaxID=1262923 RepID=R5CTW4_9BACT ------AAIKKLAEGKDAEIGVAWME--GNAMH-SMNNERLYPLMSVFKLHVAVALLKDME -RRGAAVDTTLNITPEQMRKYSPLMKQHPDGRITLPQLIRYAIAESDNNAADILIAMAGGI -DSVDREIHAMGIKDCHLSETEATMYEAPINSYANWSKPESVVWLLRKLYDGRLLSGEYDR -CIKQALAATTTGADKIKAGLSQGMTLAHKTGTGFKMADNDAGVVTMPDGRQVAIAILIKD -SKMSDADNARLMAEITKIIL--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D6KNL3_9SPHN ---ALDRAISRIGGTFDGHVGIAVRDLAARRTL-HFNGLEQFPQQSVSKLWVALTALDEVD -AGRLDLGEMVRIRPGDLTVHQPIRDIVRRDGADYAELVERAITQSDNTANDRILRRVGGP -AAVQDFLDTHGLSSIRFGTXERSKQSAYLADPLDGAPPVAVVGALAKLHRGELLSPGSTS -LXLGTLARTRSGPQRLKAGAPEDWTVRHKTGTGQQSGYNDIGLIXSPAGRTYAXAVMIAR -TREPTPVRMEMMQEVVRAVVRY- ->[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. 'Roaring Creek' TaxID=1681830 RepID=UPI0006D8272E ---ALLAKIKELAKEKDLTMQMMIVDLDSGTYV-QLGANQPIAAASTIKTPILVAFFQDVD -AGKIKLDEQLEMTADVKVGQAGELQYLPTGTISALETATKMIVISDNTATNMIIKRLGGA -VALNQRFKSWGLNSIVINNQLPDLEGT------NTISTQDLATLLSMIDRGKLIEPRSRD -RFMDIMRRPVT-NTLLPQGIGEDARIIHKTGDIAS-SVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRATYEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium faniae TaxID=570446 RepID=A0A1G4SD41_9SPHN ------SVIRNLGQSFNGHVGIAVRRIGADWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD -RGKLRLSDTTTITKKDLTLHQPSAMLVDNSGTTYSNLMDRAMKQSDNTCNDALLRAVGGP -DAVRGFLARRFISNIRFGPGERLLQSNYLANPPDGAAPSSIVRALAKLKEGDMLSPTSTR -TLLSIMGEARTGPQRIKGGVPAGWSYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A348V185_9BACT -----SRQILQRISSFRGETGLVVKDLQTGWTF-LHNDEALFPAASLIKIPIMVACFKAVE -EGRLSLAEKYVLRRQDRVGGSGLLRRMRNGRFTYEELIDYMVTHSDNIATNVIIKRL-GF -DYISQVFEELGLRDTVLNRQMMDFRAR-ENGLENYTSAREMADLLEQIYHGRCLNAAISE -RCLDVLKRQKI-NDRLPRFLPREATVAHKTGQERE-VCHDAGIVFSPHGD-YIIIVLVRT -WTGP-LTTKTFIARLSSYFYQVf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH5-D11 TaxID=1768786 RepID=UPI0008315B49 ---ALEASISQLVREFPGIAGVAVRAVDEGWTV-EAGGRRPLPQQSVSKLWVAMTVLDQRD -SGRLRLTDAVSLTPADLTLHQPSAFLVRNGITTVSDLLFRALTQSDNTANDRLLTLVGGP -SAVRAFIERKQLGEIRFGPGERLLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR -LLISTMESSRTGRARLKAGAAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD -TQRPMRDRQQLIQAVAATVT--- ->[subseq from] CubicO group peptidase (Beta-lactamase class C family) n=1 Tax=Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007 TaxID=415956 RepID=A0A5S5CZU6_9SPHI ----LQKRIAKLFAQYKGRFAYAMVDMQTGEQL-LHRATETFHAASTMKTPVMIEVFRQAA -AGKFRLTDSITVYNESIVDNSTYAYARIGTKLTWYDLVYRMITESSNLATNILIDRV-GA -KNIMKTMKSLGLKDIQVLRGVEDTK-AFEKGLNNTTTAYDLMLLFKQLAEGKAVSPASSE -AMIAILKDQHF-RSMIPARLPKDVRVAHKTGSIA-GIRHDSGIVYLPDGRAYVLVLLSGE -LED--SDARDALAAMSRVFYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OV641 TaxID=1881068 RepID=A0A1H7ASM1_9SPHN ---ALEASISQLVREFPGIAGVAVRAVDEGWTV-EAGGRRPLPQQSVSKLWVAMTVLDQRD -SGRLRLTDAVSLTPADLTLHQPSAFLVRNGITTVSDLLFRALTQSDNTANDRLLTLVGGP -SAVRAFIERKQLGEIRFGPGERLLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR -LLISTMESSRTGRARLKAGAAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYAVAVMIGD -TQRPMRDRQQLIQAVAATVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Roseibium hamelinense TaxID=150831 RepID=A0A562TGX9_9RHOB ---TLRSEVSRIAETVGEGVGASIAFPGEPPID-LINGDRSFPMMSTVKTLVSMAALDRVS -EGEMTLESQITIMEDDLSVMSPVNLTFPQAPTTLYNLIWTAIVDSDNTTPNTMMRVMGGP -ESVEAFVREQGVDEISVARNLNGLFVPLWDDPRDTTTPNAMARLLSGFLAGDVLDEERTA -ILIDIMEQTRTGKARLQGMLPPGTIVGHKTGTGHD-SINDAGWIRLPDGRTMVIAVYNRN -TA-SIEAKEQVIAQIARAAYD-- ->[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. TaxID=1872480 RepID=A0A2E1Y6P4_9SPHN ---ALQQQLGDLGEAFNGDVGIAVTQADTLATM-SYTGTKRFPQQSVSKLWVSLTALDLRD -EGALDLSEPVTLRAEDLTVHQPLRDIVRARGTDYADLINRAITQSDNTANDRLLRRVGGP -SAVEGFLRRNQISGVQFGTDERTKQSAYLADPIDGASPVGITKALARLARGDLLSENSTG -LIVSTMQRTRSGPRRLKGGVPAGWTIAHKTGTGQQSGYNDIGILTAPDGTNYTIAVMIGS -TRASYAARMGMMQEVTRSVVRY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520IF48_SPHSX ---DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIEELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3B9ZY15_9BACT ------AGLENASASYRGKVGIYLKDLHTGKFW-EYNPDRLFPSASLIKVPIMAAAFEKIK -AGELTLDTQIKLTRQDRWGGSGSLKWVREGTLSVMEIIYKMITESDNTATHMLIDYL-GF -DFLQMEFSRLGLVYTKIYPEGLNLTSG-RVARENYTTAREMADLLEQIYEGKLIDKNSSE -QMLEFLKHTKS-RSRLRRGLPLGWEIGHKTGLLRR-SCHDVGIVFSPRGD-YIIAVLTSD -VP-NYSSAKNFIDKVAKVTYKYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534HHC1_9GAMM --hKLETEVREIDARLDAVMGVAIEDLSNGGTL-FLNPDEIFPQASSIKIAVLAELYHQHQ -EGKLKLDDLYTVNTADLVADSNIMGGLTPGVITNRGLATMMIAVSDNSATNVLIDRI-GM -ENVNALLESLGLHHVRLQRKMMDLRAAVEG-RENVATPREMMTLLDALYRNKVLNPGLTD -DFFKMLSTPK--DSWIPRYLPEDVKIANKPGSLE-GVRTDSGVIFAK--RPYILCVMTTY -LR-NERDGEEAIAQLSRAAYRTf ->[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. TaxID=1153 RepID=A0A2W7A5P4_9CYAN ------SKIKELAKEKDLTMQMMVVDLDSGAYV-QVAANQPISAASTIKTPILVAFFQDVD -AGKIKLDEMLEMTADVKVGEAGDFQLLPGTKIPALEVATQMIVISDNTATNMIIKRLGGF -AVLNQRFKSWGLNNIVVKNQLPDLEGT------NTISTQDMVSLLAMLDKGKLIEPRSRD -RFMDIMRRPVT-NTLLPKGIGEDARIIHKTGDIGS-VVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRTTYDYf ->[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1PPK1_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPKR----------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pan44 TaxID=2527983 RepID=A0A517SJY1_9BACT ---RWKDRIRELAAAHKGKVAVAVSHPSSKETF-FLNEKEVMPTASLIKLAVMVEAYRQAD -AGRIDLKKLATLKEEDKVPGSGILTQHFSAGLSVRDSVRLMMAYSDNTGTNLVLDAI-GI -PATAKAMEELGYPETKIHSKVRDLSVRSVKYGLGSTTAADMVSILERLLKGELANEESTK -AMIAHLRSNPD-KETFSKHLPATAKYGYKGGAVDR-IRTAAGFIDVEGG-PLLVAVLTAE -NTDQENSAQNLIARITKEAFDRf ->[subseq from] serine hydrolase n=1 Tax=Sediminibacillus massiliensis TaxID=1926277 RepID=UPI0009884D02 ---SLQMKLEQTLERIEGEVGVTVEHLQTGEHA-SINGDRLYQTASTIKVPILCALYKLAE -QGLIGLEERVRIENEDFVPGSGVLQEMQPGLVTVKDLATLMIVVSDNLATDKLLTMI-GM -EKVEGFMRSQSLQSTFVRQSIWELLCQRDVKDNNLMSPNDMAHLLRKITDHEGLAADSCN -QILDIMSRQHF-QNRIGGELPPQVKVASKSGSLFQ-VANDVGIVYLPDG-SYTISVFTTG -IQP--KEQDNAIASISKVVFDHf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9RE75_9BACT --qKLQVSIAGTDRELDGILGVSIQDLSSGEQF-SLHGDEVFPQASSIKIAVLAELYRQAA -QGKLKLTDLYTVNSADLVVDSYIMNGLTPGVITLRDLATMMVAVSDNSATNVLIDRV-GI -ENVNALLDSLNLPHTRLRRKMMDIKAA-AEGRENISTPNEMAGLLRAVYQKKFFDAALTE -DLFKVLSTPK--DSWIPRELPDDLKIANKPGSLE-GVRNDSGIIFLANR-PYILCVMTTY -LRR-ERDGEQAISRISLAAWRMf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520ELL1_SPHSX ------NAVQALGASFKGEAGISVRDIDEGWVV-AWAGDSPRPQQSVSKFWVAIAVMDAVD -RGRLSLSDPVTVTRSDLTVHQPIRTLVGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLAEKEIAGVRFGPGERQLQARYLADPLDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium minihomine TaxID=2045012 RepID=UPI000C76C813 -----EQMLREYLNAQPGEAAVWVQDLTDGTTA-VINADAVFPSASTIKLVIMACLLEKVR -DGQMSLDDLVTMTPDMKTGGDGILKELRSGHIALEELLTLMIIVSDNTATNILIDRL-GM -EEINSTANALGMKQTVLERRMMDSQAK-KLGKDNFTCARDLALILEKIYREQCVDASMSR -LMMDLLKRQQQ-TGRLQLYLPEDLEIAHKCGDLDY-LEHDVGIVFLPKH-PYLIVVLTKD -NP-TNKEGRELIGIVSKIVWEQ- ->[subseq from] Metallo-hydrolase family protein n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A522CLW8_9CAUL ---ALQSRLDVLAAGYGEDVGIAVTDVTSGWTA-GVGQDRLYPQQSVSKLWVAIALMRAVD -EGRLDLNAWLTMDDADRSVFQPVVAEYRQGSTPMSDLLRRALVESDNAANDRLMRELGGP -EGVRAALDDMGLTNVKVGAYERDLQAAYVAAPLDGASPAAITAALAALSRGALLSEESTL -RITALMTAARTGPRRLKGGLPAGWSIAHKTGTGQQGGINDVGLLTAPDGRTYAVAVMLPR -TRHSVTARLAFMQSVSRAVVEQw ->[subseq from] Beta-lactamase n=1 Tax=Nostoc linckia z16 TaxID=1628751 RepID=A0A2C6V676_NOSLI ----LSSQIRTLLANYSLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQDID -AGKIKLTDKLVMRRDLRVGEAGTMQKPVGTKFSVLETATLMMTISDNTATNMVLDRLGGA -AKVSQRFRSWGLQNTAMQNLLPDVGGT------NTTSSKDLVRLAALVANNRLLSPNSRN -QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=A0A649W1R7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-HYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEMHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLITAIPGDPRDTTSPR--------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Carboxylesterase, beta-lactamase family n=1 Tax=Synechococcus sp. (strain JA-2-3B'a(2-13)) TaxID=321332 RepID=Q2JKE0_SYNJB ---ALQERLAALADQPGLTAGALFWEVETGAFA-GVRPDQAFPAASVIKIPILLAFFQAVE -TGQVRLDEQLTLREDLKGGGAGVLQTRPLGSVSALEAATLMITLSDNFATNLIIDRLGGQ -ETLNQKFRQWGLQHTQISWWLPDLEGT------NTSSPRDMVWLLSQVEQGRMLNRRSRD -RFLDILWRTQR-LSYFRPNLGQEVRIAHKTGTLGS-VVGDAGILDLPNGRRYVAAVWVKR -ETPNDPRAEGLIASLSQAAYEFw ->[subseq from] Serine hydrolase n=1 Tax=Alphaproteobacteria bacterium PA2 TaxID=2015570 RepID=A0A257J1R0_9PROT --eALQRDLDSLAEAFGETVGLAIVDISANWMV-DVRGDEAFPQQSVSKLWVALTTLSAID -RGAAGLDDAVVLTESDRSVNQPVSYLITPEGTTVEDLLRRALIESDNAANDKLMALAGGP -GAVRRLLHEKGLEGIALAEDERHLQAAYLSRPYDGARPGSVAVALGRLQAGKLLSKESTR -WMLDTMARATTGPNRLKGGLPDGWRIAHKTGTGQQGGINDVGLITAPDGRTYAVAVFLQR -THNPVSERLAFMQAVSQALVAHw ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter gaetbuli TaxID=266952 RepID=UPI001360E777 --kALQDRLAAIGKAFPGEVGIAVVDVSSGARM-HFEGRKPFPQQSVSKLWVAMTALDLVD -QGALDLAEPVSIERRDLTLHQPIREIVRTRGTDYFDLFERALTESDNTANDRLLRRVGGP -TAVDGFLRREGIIGVQFGPDERTKQSKYLADPVDGASAIGIAQALARLAKGDILSPASTS -FILGTLERTKSGPNRLKGGTPAGWVMAHKTGTGQQSGYNDVGVLRAPDGSQYAIAVMIGR -TRSSFSSRFEMMQAVTRAVADH- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroidaceae bacterium TaxID=2212467 RepID=UPI0012B84D46 --tAIEQKILQAIQGKNATVGAAFSI--DGQLF-TFNDEHRYPLMSVFKLHVAIAALQKME -NECIAPDSLRFIESLQIHKYSPLRELYPERNLSYADLMRYAVSQSDNNACDILIDYLGGI -DIVKDRIDKLGITNYNLTETEETMHSRISNCYNNWSTPSSTLQLLEKLYNEPILNETHTE -FLKNILIETSTGKDKIKAGLPDNIALGHKTGSSDKIGDNDTGVIYLPNGKLCFLAIFIKD -SRESDQTNAQIIADIARIIYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A2E8ED93_9ARCH --------LNDAVSGLKGTLGVSVKHLETGETA-SINGGDLFPTASVFKVPVIIEFFRQLE -SRTVSLDEKKMLAEADKVPGSGILKELSNGLLTYGDLLRLMMILSDNTATDLVIKRV-GK -DRVNATIRSLGLEETKVVADCRDILFSLGVDENDVTTPSEMLRLLEMIVEGKAASRESCN -EIMEIMSKCQTGGNRIPKYLPAEMELTHKTGSLP-GIRNDAGLVTIQTGERYILSCFIKG -AA-DVYAAEETIAMVSKSVYKYf ->[subseq from] Serine hydrolase n=1 Tax=Altererythrobacter sp. TaxID=1872480 RepID=A0A2E6K8U3_9SPHN ---ALQQQLGDLGEAFNGDVGIAVTQADTLATM-SYTGTKRFPQQSVSKLWVSLTALDLRD -EGALDLSEPVTLRAEDLTVHQPLRDIVRARGTDYADLINRAITQSDNTANDRLLRRVGGP -SAVEGFLRRNQISGVQFGTDERTKQSAYLADPIDGASPVGITKALARLARGDLLSENSTG -LIVSTMQRTRXGPRRLKGGVPAGWTIAHKTGTGQQSGYNDIGILTAPDGTNYTIAVMIGS -TRASYAARMGMMQEVTRSVVRY- ->[subseq from] class A beta-lactamase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI0013E2DAF6 -------------------MGISIKGFEKEDTI-NINANDTFPLMSVFKFHIALAVLQRVD -DGVLKLTQKVLVEKSQLHSWSPMRDQYPHGQLSLDEILRYTVSNSDNNGCDILLNLIGGA -KGLQKYIRSLGADDFTVSVNEFQMRS-WENSYLNYSTPMETTKLLEKFYNGLILKANSTD -YLYRLMVETTRGTRYMKSGLPQAAEIAHRPGLSGRIAMNDVGIVKLPNGQYFIISIFLKD -IMQDDRQAEEFFSEVARLTWEYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5I719_9SPHN -------VVRNLGQSFRGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPTAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVGIPERWALMQAVAKAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium yanoikuyae TaxID=13690 RepID=UPI000262C200 ----LVSVIQNLGQSFRGKVGIAVRRVGADWTV-AYNGNALFPQQSVSKLWVSMTFLDAVD -RGKIRLADSTTITKKDLTLHQPSAAMVGSGGTTYSDLMRRAMTQSDNTANDTLLRAVGGP -DAVRGYLARRHIANIRFGPGERLLQSNYLASPPDGAAPASIVQALAKLKEGDMLSSVSAR -VLMNFMEEAKTGPQRIKGGVPHSWTYMHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVSIPERWQLMQAVSRAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8ZUQ9_9BACT ----LRERLTKIAASFPGKVGIFVRNIETGEET-GVNPNDEFPMASTYKVAIMVQVFREAD -AGHLSLAERVPLSDADRRLGSGLLPYMTPGLPTIHDLVLLMITLSDNEATDLMLKRV-GA -RNVTAMLRQLGIQDMRVDRSTEELIGAFVDDARDHTSPKAMAELLTKIFRAEAATEKSCH -DMLEIMEQQQL-RTRIHRYLE-NTTVASKNGTIGY-VTNDVGIVSVGKH-HLVVSAYTLK -ANVTTEQAEELIGRLARAAYSYf ->[subseq from] Serine hydrolase n=1 Tax=Calothrix elsteri CCALA 953 TaxID=987040 RepID=A0A2A2TG31_9CYAN -------QIRGLLASYSLNPGIFFLDLQTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLKVGESGTMQYKPGTKFSVLETATLMMIISDNTATNMVLDRLGGT -TKVNQRFRNWGLPNTAVRNQLPDIAGK------NTTSSKDLVRLAALVHNNRLLSSNSRN -QVLGIMRRVKT-NTLLPAGIGKGATIAHKTGTLRF-IIGDAGIIDMPNGKSYLAGVLVQR -PNHD-PRAGAFVREVSRRVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. KVJ20 TaxID=457944 RepID=A0A1E2WIQ0_9NOSO -----SSQIRALLATYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLRVGEAGTMKKPVGTKFSVLQTATLMMTISDNTATNMVLDRLGGV -AKVNQRFRGWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVSNNRLLSPNSRN -QVLGIMRRVKT-NSLLPAGIGKGATIAHKTGTLRF-IIGDAGIIEMPNGKSYLAGILVQR -PNHD-RRAGDFVREVSRRVYNY- ->[subseq from] Uncharacterized protein n=2 Tax=Sphingomonas sp. Leaf230 TaxID=1735694 RepID=A0A0Q4IWD7_9SPHN ---------------------------------------------------LAAMLLAKAD -AGQIDLRETLHWTKEDMLSVSPVTTVNLGKGLSVQELARAALVTSDNTAANVLMRRFGGP -SQLTAFWRSIGDKSSRLDRYEPELNVTPPGTDLDTSTPAAMAATTAAIVHGTILTADSRA -MLRAWMAEVKTGQDRIRSGFPTNWISGDKTGTGIKHIYVDLAFGGPAGRSPLIVTAYFEP -ARPMARDAVAVLATVGRIAA--- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E0WY21_9PLAN ---DLASELTALAESHDGDVAIALKYLPTGESF-AYRADVPMPTASLIKLPLMATVYHAVD -AGRLDPQQMLTLAEEDKVPGSGILTEQFSPGLSLHDAIHLMIRHSDNTATNLVAGAV-GL -AETAKYMEELGMPETKLHRDTSLFPERSQQYGLGSTTAADQVKLLELLATGQLVSPKSSE -AMLAHLYACED-DSKLARSLRDGLKIAHKTGAVNK-VRTDAALIDLPGGR-LAICVLTAN -NAGDKNAAEILCGRIARRAVRHf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc punctiforme NIES-2108 TaxID=1356359 RepID=A0A367R3E4_NOSPU -----TSQIRTLLASYTLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA -AKVSQRFRSWGLQNTAMRNLLPDIGGT------NTTSSKDLVRLAALVSNNRLLSPTSRN -QVLGIMRRVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas ginsenosidivorax TaxID=862135 RepID=A0A5C6UI35_9SPHN ---QLAATIDALHRGFAGKAGIAIRAVDEGWTV-EAGGRLSLPQQSVSKLWVAITLLDLRD -QGKARLDEPILVRPEDLTLHQPIAMLVKGAGTTVGDLLTRALTHSDNTANDRLLTFVGGP -GAVRAMIERKRLGDIRFGPGERLLQAAYVANPPDGAAPIAIADSLARLARGELLSETSTR -ILLDTMGASVTGRARLRAALPPGWTIQHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMVGD -TLRPIRERQQLIQSVAAAVAS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=T1Z0T9_ECOLX ------------------------------------------------------------- -----LLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGSGAFRPGPPASWVCGIKTRPAANGTTNDIAVIWPKDRAPLILVH---- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Larkinella terrae TaxID=2025311 RepID=UPI0012AD8416 --qSLSEKLTAYLQQLQARVSVAFESLTDHSAF-AHRADELVPSASVIKIPILIETMERVK -SGQFDLEKIHMLQASEKTGGSGVLQTYPDQSLTNREVLTLMMTRSDNTATNILIREL-GM -ENINQRMRTLGLTQSQLNRMMMDTLAA-KLGRENRVTAFEMNALLKKIYRHEVATPALCE -QMIDILKRNTD-QTTFRLFLPKSAVIAHKTGELSY-VRGDAGIFYVS--KPFLLSVFVQG -TT--TPEAEKIIGEIAQICYQQy ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter lutipelagi TaxID=1964208 RepID=UPI0010F6969C ----FEQRIAQLANGSDGRIGVYAMDLSTGQEI-GILADQRFPMASTSKVAIAATYLAGVD -NGRWSLTSEFRLPR------------R-GGGVPAHTLLDLMISKSCNDCTDALLSAVGGP -SAVNAWMRNAGIGGFQLNRDIATLIRASRVDSRDSATPRAMGQLLAGIHQGRWLSASSRR -VLLNAMAETTTGKNRMRSALPMHANLAHKTGTLSR-TASDIGIFYTPDGRAIAAAIYVTG -QSPSLA----------------- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacterales bacterium 68-7 TaxID=1895737 RepID=A0A1Q3JFC7_9PROT ---RLRREIPEIAKRCPGVLGVAIGASRGGDLY-TFNAARSFPMGSVFKAMLGAAVLSESE -AGQFALSETVEVRDIDLSPHSPVADAWPATTYTLDDLLKRTVSDSDNTAADILLKRIGGP -GMLTAWLESKGSEGLRVDRYEREMQPAFLIDPRDTATPSGMMNWLDGLAAGLLLSPAATT -RLLKMMTETPRASGRLAAATPAGAELAHKPGTGWNLATNDVGVYTLKDGRQLTVVAFLAG -ATLDETGRDKAIADVGRAAI--- ->[subseq from] Serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii CENA303 TaxID=1170769 RepID=A0A1X4GA50_9CYAN -----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNKNFPAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNILISKLGGK -ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] Serine hydrolase n=2 Tax=Bacteria TaxID=2 RepID=A0A534HZ32_9GAMM --hKLETEVREIDARLDAVMGVAIEDLSNGGTL-FLNPDEIFPQASSIKIAVLAELYHQHQ -EGKLKLDDLYTVNTADLVADSNIMGGLTPGVITNRGLATMMIAVSDNSATNVLIDRI-GM -ENVNALLESLGLHHVRLQRKMMDLRAAVEG-RENVATPREMMTLLDALYRNKVLNPGLTD -DFFKMLSTPK--DSWIPRYLPEDVRIANKPGSLE-GVRTDSGVIFAK--RPYILCVMTTY -LR-NERDGEEAIAQLSRAAYRTf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=A0A4R2PG13_9SPHN ----LLNAVQALGGAFRGQVGISVRDIDEGWTV-AWGGDSARPQQSVSKLWVAIAVMAAVD -AGKLSLDDAITVRRSDLTLHQPIRAKVGAAGTTIGELLRGAMTHSDNTCNDVLLWRVGGP -IAVRRLLRDKGIEGVTFGPGERLLQARYLAAPYDGASANGITLGLSLLAQGKLLSARSTA -SLLALMRQSRTGPLRLRSGLRPGWTLAHKTGTGQATGYNDVGLIVAPDGHRYAVAVLIAS -TREPIPVRMRLMGDVTRALVA-- ->[subseq from] Putative beta-lactamase protein n=1 Tax=Stanieria sp. NIES-3757 TaxID=1807358 RepID=A0A140KB26_9CYAN ---SLKSKLQTLASQYKLQPAIFLVDLDDNSYV-SIQGAVTIAAASTIKLPVLVAFFQDVD -QGKIHLDEKLTMNKEDIGSGSGGMQEKPGTQFTALEVASQMITISDNTATNMLIKRMGGA -EQLNQRFLEWGLTQTVIRNPLPDLEGT------NTTSPEDLGNLLINLERGKFVSLKSRD -RMLKIMSNLAR-NTLLPIGLETNATIAHKTGDIRS-VLGDVGIIDMPNGKRYVASVLVKR -PDND-PKAKEFIQKMSQVAYQH- ->[subseq from] serine hydrolase n=1 Tax=Myxosarcina sp. GI1 TaxID=1541065 RepID=UPI000907A803 ---ALQAQLEDLAAQYQLEPKVFLADLDTQSYV-SIDGQTPLSSASTIKLPILIAFFQDVD -AGKIDLQEELTITEEVVGGGSGGMQYPIGTKYTALETVTLMITVSDNTATNMLIERLGGQ -AALNQRFIDLGLTATRLQNPLPDLTGT------NTTSTEDLGNLLVQLARGELVSIQSRD -RLLLIMRSIVR-NTLLPEGLEAGAIIAHKTGDIKS-VLGDAGIIDMPNGKRYIASVLVKR -PDND-PQAKEFIQQMSHLVYQYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacF n=2 Tax=Planctomycetes bacterium TBK1r TaxID=2527963 RepID=A0A518KXW4_9BACT --dDLARRITPLISDYQGDVAVGIKNLSGEGEF-WYRHDQPMATASLIKLPLLVATYQQID -SATVDPAQLIELTREDQVPGSGILSQHFSPGLPLIDAIRLMIRYSDNTATNLVIDQV-GL -PTTTESMKSLGLVHTQLHAKVYRRDTAPKRSQRGSTSAADMIKLLEGIHTHQVASKTSCE -AMIGHLLSCDD-QVKLAAGLPSGTKIAHKTGGVSS-VRTDAGIIFGPGEQAFAICVLTEN -NKSADSAPHRLIADIGRAAYQAf ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. CAG:299 TaxID=1262792 RepID=R6Z6E6_9CLOT ---EMKQDICAFLQGKQGKVCVSFYDLNAGEGF-SIRGTERVPSASTIKLVILAEAMRRVR -EGELSLEQTITVTEEMRTGGDGILKELLPGHFTLREILTLMIIVSDNEATNILIRML-GM -DSVNRMASELGLKEACLGRLMMDSEA-KKQGKDNYICADDMTEIFRQIYAGQCVGEEESR -LMMDILKRQQQ-GGRLQLYLPEEIETAHKCGDLD-ALENDGGIIFLPGR-PYILTVLTSE -ME-SNKEGREVIGHISRIVFD-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X2Y4_9BACT ----LSETLKKLCDTVGGKVSVAVVHVETGKLA-TVDASNELPLFSVFKLPLAITVLKRVE -EGSLKLDQNVHIGPDELIVGTRANSQRWQNPFTIKQLLEFSIIESDNTSSEKLLQLVGGP -QAVTERMLSFDLQQINIKTTIRDYVAT--RSNPNTGSAAALVKLLSKLQNGELLQRAQTD -LVIGMMERAKTGLHRLRGNLPQGTKVGDKTGSGDPNSTNDVGLITLPNGGHLAMAVLLHE -STLSDEAQEKLIADLARTAFDAy ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas virosa TaxID=544645 RepID=A0A413IPU7_9BACT ---GLEEQLRKVIANKKAQIGIAVI-INSKDTI-TINNDARYPMMSVFKLHQALAVADYCE -KKGLSFDTSIYIRKADLKTYSPLRDLYPDGELPIKELLEYTLHLSDNNACDILFLQTGGT -EATDHYIRTLGMRHFAIKATEDEMHQDKNKCYLNWSTPLETVRMIELLLNVPLFDDEYQK -FIKTTMMSCETGKDRLARPLQNKAILGHKTGTGDRNGMNDVGFVYLPDGQSYTIAVFIKD -SEESEAATARIIADISKTVYRH- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=R9IDW2_9BACE --kAIENALQEYIKGKDARIGVAVI-INGKDTA-SVNGNRDFPMMSVVKFPLALTVAHWID -TNGMSLNDSITFRKNDLDEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFNRFDAEMRNTSLSYS -VIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGVRYSIAVFVAD -SGYDMARTSAIIAEISRIVW--- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1J4A0_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEVIPNDE---------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_2_20CM_2_66_4 TaxID=1803462 RepID=A0A1Q7AH46_9BACT -----RAHIETLIARSGADVGLAFRTLDGRDEL-LIQPDVEFHAASTMKVPVMIELFRKAR -AGALKLDDRIPVANESIVDGSPYKYKHVGGAMSYRDLCEAMITVSSNFATNLLIERL-GA -KNVQRTTESLGAPGMHVLRGVEDDK-AFRQGLNNTTTARGLMTLMEKIAKGEAVDKPSSD -EMIAILERQHF-NDRIPAGLPEGTRVAHKTGEITK-IQHDAAIVFAE--RPYVLVILVRG -LQ-DARKGSALAADISRVIYE-- ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes communis TaxID=2585118 RepID=UPI0002E7B0D1 ----LERDLCRAVRGVDAEVGIAVVR--EGRVIaSVGGDRPMPAMSTFKFPLALAAAARLD -SLGLPLSAQLEVTGDDLWPWSPLREAHPAGGFSFGELLRYTVAESDNCACDRLIREIGGI -GALQRYVEGLPAEGLDFRMTEREMSGAPDAQRRNRATPEAMALLLDRFRHDSLFASEYRD -FLWQTLCTTTTGMNKLRAGLPDGTTIGHKTGSSDRDADNDLGYVELSDGSGYAICVYVAE -TALSDGETAALIAEISRLVWQ-- ->[subseq from] Uncharacterized protein n=3 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9QU62_9BACT ---AMVASLENLAYNYSGHVGIYIKDLNSDKVW-EYNPDRLFPSASLIKVPIMIAVCDKIK -RGELSLDTQIKLTRRDRAGGSGSLKWVREGTLSVMEIIYKMITESDNTATRMLLDYA-GM -DYFQRAFEQMGLVYTKIYPEGFSLTSGWVA-RENYTTAREMAGLMERIYKGEVVDRNLSE -FMLEVLKHNKS-RSRLRKGLPLGWEIGHKTGLLRR-SCHDVGVVFSPRGD-YLISVLTSE -VP-NYSSAKGFISSVAKLTYKYy ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013DF5B2C ------------------------------------------------------------- ---------------------------------------------SDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAALI--- ->[subseq from] ClassA n=2 Tax=Bacteria TaxID=2 RepID=A0A127SAZ6_9BACT ------------------------------------------------------------- --------------------------------MTIREICDAAVRQSDNTAGNLQFTLLDGP -NGFKQSLSKIGDTVSEPSRIETELNDAVPGDIRDTSTPKQLALNLKEYATGDILSDDKKE -IFIDWMSNNATGDELIRAGVPSDWIVADKSGAGSYGTRNDIAIVTPPNKKPIFVAVLSKK -AEQDAEYDNKLIADATKIIFD-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium KOR34 TaxID=1938618 RepID=A0A5C5VHS6_9BACT ---SFEASLTELLEGHRGTVAAAAKHLPSGKEF-RFNADQPMPTASLIKLSIMAAAFKAEA -DGRLKMSDEVSLKEEDKVPGSGVLTENFSAGMPLHDAIRLMIAFSDNTATNLVIDQV-GL -PATTEYMEELGLPSTRLHAKVFRRDTSIAPERSGSTTASEMIELLEQINDRKLISSQASE -AMYQHLLACES-RSKVPRYLPEDTPVAHKTGSVS-AARCDAGIIESPKG-PIAFCILTGD -NKGDENEAELLAAEFGKAIYTHy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9MWU2_9BACT --qKLEASIAEVDHNLDGVMGVAIEDLTSGQKY-QLRENEVFPQASSIKIAVLAELYRQAQ -QGKLKLTDLYVVKSVDLVGDSPIMNGLTPGVVTLRDLATMLAAVSDNSAANILIDRL-GM -ENVNSLLDSLGLTHTRLRRKMMDLKAAG-EGRENISTPGEMMTLLDAIYRGKVLNKSLTD -DFFKLLSTKKN--SWIPRDLPENLKIADKDGELE-GVRNDSGVIFLENR-PYILCVMTTY -LRRE-RDGEEAISKISV------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ZDH117 TaxID=2305907 RepID=A0A396RV78_9SPHN ----LVETVRFLGREFEGRVGIAIRRVDTGWSV-DWQGDLPMPQQSVSKLWVAMTALDARD -KGMLRLDQPVTVTRSDLTLHQPIASLVKGDGTDPDELLRRAMTMSDNTANDKLLSLAGGP -AAVNRFLAGKGLTGIKFGPGERLLQAAYVANPPDGATANGIARALAKLHRGELLKPDSTA -YLLRYMEESKTGRARLKGAMPPGWRLAHKTGTGQTAGFNDVGLITSPDGTTYAVAVLIGR -TGKPVRDRQSLIQAVATTLIA-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. S-NIH.Pt15_0812 TaxID=1920129 RepID=A0A430BMR5_9SPHN ------------------------------------------------------------- ----------------------------------AAKVLEAMIVHSDNVAADQLFAALGGP -AAVQQWVWSQKIIGMRVDRTIAQLLRGHLADSKDVATPVAMVQLLKALDSDTVLAPQSRS -FLLGLMAKCRTGTRRIRALLPAGTVVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GN----DRQPVIAQLSRMIYDRf ->[subseq from] Beta-lactamase n=1 Tax=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) TaxID=479434 RepID=D1CAH8_SPHTD ---AARTELDDLIRRAPGTVGLVIEDLTTGERL-EWSPETQFLAASIIKIPILVEGLRQAE -EGTVRLDQMVPVPDDAKVGGFGILKELTSVTISLLDLLTLMIIVSDNTATNLCIDVL-GV -ESINRTIASLGLTGTQLQRKMMDYEA-RDRGLENFTTPADVARLLRLIATRQILTPEACD -LALDIMARQQV-RDRLPLYLPDDMRVAHKTGELS-GVRHDAGVIFFESG-PVIVVALTQG -FSDQGGDASALIAQIPRVL---- ->[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JX38_9ZZZZ ------------------------------------------------------------- --------------------------------------------MSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEVDKVTGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Scytonema tolypothrichoides VB-61278 TaxID=1233231 RepID=A0A0C2LL52_9CYAN ---QLSSQLKTLIARYSLSPGMFFLDLDTGNYL-DFNGEKIFPAASTIKFPILVALFQEVD -AGRVKLNETLVVRRDLKAEGSGVLQKPVGTKLSVLDTATKMITISDNTATNMIIDRLGGI -AKLNQRFRSWGLQNTVIRRQLGDFKGT------NTTSPKDLVRLSALVANNKLLSSTSHS -QALGIMRRVEN-KRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-KRARDFISQVSKLVYG-- ->[subseq from] Putative Beta-lactamase n=1 Tax=Bacteroides finegoldii DSM 17565 TaxID=483215 RepID=C9KU58_9BACE ------------------------------------NNDIQYPLMSVFKFHQAVALADYMD -KKRLPLGTLLSIKKSDLKPYSPLRDQFPQGGMSIADLLKYTLQQSDNNACDILFNYQGGP -DSVNRYIQSLGIRDCEITHTENDMHEDLDLCYSNWSTPLAAAKLLEIFRRKTLFDEAYKN -FIYQTMVECQTGQDRLVALLGKGVTVGHKTGTGDFNGCNDIGFVLLPNGHAYSIAVFVKD -SAESSLKNSKIIADISRIVYKY- ->[subseq from] Uncharacterized protein n=2 Tax=Prevotellaceae TaxID=171552 RepID=A0A0M0N1Z8_9BACT ------AAIKKLAEGKDAEIGVAWME--GNAMH-SMNNERLYPLMSVFKLHVAVALLKDME -RRGAAVDTTLNITPEQMRKYSPLMKLHPDGRITLPQLIRYAIAESDNNAADILIAMAGGI -DSVDREIHAMGIKDCHLSETEATMYEAPINSYANWSKPESVVWLLRKLYDGRLLSGEYDR -CIKQALAATTTGADKIKAGLSQGMTLAHKTGTGFKMADNDAGVVTMPDGRQVAIAILIKD -SKMSDADNARLMAEITKIIL--- ->[subseq from] Penicillin-binding protein, transpeptidase n=2 Tax=Lyngbya sp. (strain PCC 8106) TaxID=313612 RepID=A0Z083_LYNSP ---TVKQQILALTENSDLKPGILLVDLDTGGYV-DINSESAFAAASTIKVPILVAFFQAVD -EGKISLNEVLTMEGQHIAGGSGDMQYQPSGTYTALETATKMIVISDNTATNMLIERLGGA -EFINQKFLDWGLHNTVIRDVLPDLRGT------NKTTPKDLVNLLTQLNQGGLVSMKSRD -RIFRIMEKTEN-DSLLASGLGRGATIAHKTGNLKS-VSGDVGLIDLPNGKRYLLAVLVER -NDED-SAAESLIRNISQTVYESf ->[subseq from] serine hydrolase n=1 Tax=Sphaerobacter thermophilus TaxID=2057 RepID=UPI00069026B2 ---AARTELDDLIRRAPGTVGLVIEDLTTGERL-EWSPETQFLAASIIKIPILVEGLRQAE -EGTVRLDQMVPVPDDAKVGGFGILKELTSVTISLLDLLTLMIIVSDNTATNLCIDVL-GV -ESINRTIASLGLTGTQLQRKMMDYEA-RDRGLENFTTPADVARLLRLIATRQILTPEACD -LALDIMARQQV-RDRLPLYLPDDMRVAHKTGELS-GVRHDAGVIFFESG-PVIVVALTQG -FSDQGGDASALIAQIPRVL---- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9F9Y6_9BACT --qKLEATIGGVDHNLDGVLGVAILDLATGQKY-VLHADAVLPTASSIKIAILAELYRQAQ -QGKIKLSDLYTLQSSDLVGGSGIAGALTPGVLTIRDVAALMISVSDNSATNIIIDRV-GM -ENVNTLLDSLGLTHMRLRRKMMDVKAA-AEGRENIATPREMVQLLEDLYRGKVLNKQMTE -DFFAILSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGNH-PFVISVMTAY -LRRE-KDGGDAIIRIATAAYQMf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A654DHI4_9SPHN ---DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] serine hydrolase n=2 Tax=Sphingomonas TaxID=13687 RepID=UPI001443B383 ---DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter lutimaris TaxID=1538146 RepID=A0A395LG17_9SPHN ----LDDRLFAIGSDFAGKVGIAVHDPARGRMM-HFNGTDLYPQQSVSKLWVALTALDQAD -RGRLDLSETGTVRREDVAVYSPIRGGVVANGTSWRDFMKRAITASDNTANDMVLRRVGGP -DAVRATLARKGFSDIRFGPGERPMQSDYVDDPVDGATPVAIAAALGELHEGALLSEAGTQ -QFLEWLGQVKSGPNRLKGGLPAGWSIGHKTGTGQQAGYNDVGILTAPDGSVYTVAVLVGR -TQVPIPARMEMMHAVVRAVAG-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZNU1_9BACT -----RAHIETLIARSGADVGLAFRTLDGRDEL-LIQPDVEFHAASTMKVPVMIELFRKAR -AGALKLDDRIPVANESIVDGSPYKYKHVGGVMSYRDLCEAMITVSSNFATNLLIERL-GA -KNVQRTTESLGAPGMHVLRGVEDDK-AFRQGLNNTTTARGLMTLMEKIAKGEAVDKPSSD -EMIAILERQHF-NDRIPAGLPEGTRVAHKTGEITK-IQHDAAIVFAE--RPYVLVILVRG -LQ-DARKGSALAADISRVIYE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas aerolata TaxID=185951 RepID=A0A2T4YP51_9SPHN ---DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRIGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Weissella cibaria TaxID=137591 RepID=UPI00143F48C7 ------------------------------------------------------------- --------------------------------------------MSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPRLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGAS----- ->[subseq from] Class A beta-lactamase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8Q036_9ACTN ------------------------------------------------------------- ----------------------------ATTGMTVADLCDASLTVSHNTATNLPLDLLGGP -TAVTAFAPGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLGGGLQPADCE -RLTTSLVANTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Desulfovibrio sp. An276 TaxID=1965618 RepID=A0A1Y4D2C1_9DELT ---EIAPTLADLERRFACDISLAALDVQGGQKV-LYRADNRFAFCSTFKFFLVAEVLRKAD -ADRSLVGKRLFWKENEEQEWSPATRGRGGEGMSVIALCEAAMTLSDNTAANLLLRLLGGP -FAMTKCMRALGDRDFLLCDYEPRLNYENRLPQANTATAAGFLQAMRTLLFDRSYPDFSRN -LLLQLAGKTRTGTGRIQASLPKGATLFHKTGTGF-GNVHDLALVRYPNGRECLLVIFTKN -TQNVEKEDQ-------------- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_59_9 TaxID=1797952 RepID=A0A1F9VP73_9BACT ----MIASVQERIQRNPGKVGIYIKDLRNDRVW-TYGENEMFPSASLVKLPIMATVFQRVQ -EGKLSLDKRIAVNRRYRMGGSGRLKWFRDGSFTLRDVIQWMITESDNTAMKMAIDTV-GF -AAFQEELPRFGFRATQVNPEGLSLSSG-RVSRENYTTAAEMGMFLEKLYRKELVSPTASE -IMTELMKKLPT-RKRLATGLPYGWQIAHKTGLLRQ-ACHDVGIVYTPEGD-YIICVLTGK -NS-SYRRAKELIASVGKTMHQYf ->[subseq from] Serine hydrolase n=1 Tax=Peptoniphilus sp. HMSC075B08 TaxID=1739525 RepID=A0A1F0GQW5_9FIRM --rRLENTIENIVEESSANISVSFYDLDQGEGF-SINGDKRVPSASMIKLLILLKALDECD -KGKINLEDTINLDDHDKVDGSGILKELSNNHFSIRELLTLMIIVSDNTATNILIDLL-GM -EEINKIGNDLGLEKTSLERKMMDSNAR-EKGLDNFTSSNEILKLLKMIYDKDFVSEDFSD -LALDILLRQKE-RQRLQRYLPEDLKIASKSGDLDN-LENDGGIFFTENK-NYILVVLVNQ -AK-SNVLAKEIIGEISLKIYK-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Bacteria TaxID=2 RepID=I1V598_9BACT -------------------------------------------------FMAASAILKQSE -TQTELLTRRISLKKSDLVNYNPITEKHLDTGMTIGELAAAALQYSDNTAMNKLIEQLGGP -QKVTAYARTLGDNTFRLDRTEPTLNTAIPGDDRDTTSPRAMALSLQHATLGTALAEPQRA -QLVEWMKGNTTGGMSIRAGLPATWVV---------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Stanieria cyanosphaera TaxID=102116 RepID=UPI0012375CED ---SLKSKLQTLASQYKLQPAIFLVDLDDHSYV-SIQGSGAIAAASTIKIPILVAFFQDVD -QGKFRLDQELTMNKEDIGSGSGSMQEKPGTQFTTLEVATKMITISDNTATNMLIKIMGGA -EKLNQRFLEWGLTETVIRNPLPDLEGT------NSTTPEDLGNLLINLERGKLVSLKSRD -RMFTIMSNLVR-NTLLPVGLEADATIAHKTGDIRS-VLGDVGIIDMPNGKRYVASVLVKR -PDND-PQAKEFIQKMSQVAYQH- ->[subseq from] Beta-lactamase, putative n=1 Tax=Acaryochloris marina (strain MBIC 11017) TaxID=329726 RepID=B0CCE0_ACAM1 ----IKRQIQAWAAQSELKPAMFFLNPSTGEYL-DINGAKSISAASTIKIPVLLAFFEDVD -AGIIDLDEPLVMRPDLVASEAGSMQEPVGTTFSALDTAEYMIAISDNTATNMLIDRLGGA -EKLNQRFKSWGLKHTTIRNPLPDLEGT------NTISPQDMAALMLKLKDEDLLSSTSRE -QALDILRQTVT-NTLLPQGIEKDADIAHKTGDIGS-VVGDIGLIDMPNGQHYVAAILVQR -PHND-PRAQELIRKISKLTYKTf ->[subseq from] Uncharacterized protein n=2 Tax=Pelosinus sp. UFO1 TaxID=484770 RepID=A0A075KJX0_9FIRM --eELRKKIEHVLARYTGRWGIVIQSHTTGESV-EINPEMIFPSASMIKVPILYEVVRQTA -SGLISLDESLVVTDHFRTGGAGILKERPNISMTVRELLTLMIILSDNTATNMLIDLV-GM -DSVNKTMKDLGLGQTVLRRRMMDFEAALAG-KENDTSAADLAHLFSIIYGNSKLPTEYSE -LMLDILTRQQV-QDKLPFYLPEETVIAHKTGTLS-GVEHDGGILFLPGG-PYIICILTAD -LTVN-FQGLQLVASLGKEIYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Larkinella arboricola TaxID=643671 RepID=A0A327WPN0_9BACT -----------------VQVSVAVEELEGKTQF-YHRADERPPAASVIKVPIMVETMEQVK -TGQFDLEKIHILQDAEKTGGSGILKTYPDQSLTNREVLTLMMTHSDNTATNILIREL-GM -DNINQRMRSLGLTRSQLNRVMLDTMA-VKQGRENRVTAREMNALLRKIYRKEVATPALCD -QMIEILKGNRD-QKTFRMFLPPSAVIAHKTGELTY-VRGDVGIFYV--RKPFLLSVFVQG -TT--TEDAERIIGEIAQICYNQf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8HPF0_9BACT --eHVQRQLRDVASSFDGVMGYYVVDLTDGRTF-GALQDDVFPTASSIKLALIYELFKQVD -EGRIALEDVRPLNPAFKVGGSGVLHELTTPSLSIRDYATLMVVLSDNTATNVLIDAV-QM -TRVNDRMTALGLGHTKLRRRMMDREAALRGD-ENVSTPAELAKLLQIMYRGDGLTPGSRD -TLIAILKKSKD--TPLRRGVPPNVDVANKPGDLE-GVATDAGIVYVKNR-PYVLAVMTSY -AN-DGGGGARAIEAASRAVYDYf ->[subseq from] Beta-lactamase n=2 Tax=Raphidiopsis TaxID=244599 RepID=A0A1Z4VBW5_9CYAN -----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFPAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK -ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELANLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Prevotella sp. MGM2 TaxID=2033406 RepID=A0A2L2WWK4_9BACT ----LQAKIEEVIAPYDAKIGVAVIV-NGLETT-TVNNTADYPLMSVMKFHQALAVANFLQ -HEDGQITDKIYITPEQLLPWSPLRDQYPGGGVSIGDLLRYTLQQSDNNACDILFNLIGGP -RYVNRYIRSLGLRQTVITATEAEMHASEKACYANRTSPLDAARLLERFETRMLFSHDVQS -LIRRLMITCQTGMDRLPLPLETKAVIGHKTGTSDWTGTNDIGFVRLPSGQRYVIAVFVKD -SAEAPVTNARIIADISRTVFEH- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobium sp. YG1 TaxID=2082188 RepID=A0A2Z6AFN8_9SPHN -------VVRNLGQSFRGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPTAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVGIPERWALMQAVAKAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AAP5 TaxID=1523415 RepID=A0A4P6XB01_9SPHN ------------------------------------------------------------- ----------------------------------AAKVLELMIVRSNNQAADQLLAAVGGP -AAVQQWLSSQNIIGIRVDRTIDQLLRGHLADIKDVATPVAMVALLHKLDSGAVLTAQSRA -FLFELMRRCETGTRRIRAMLPAGTPVEDKTGTLD-GVTNDVGFITMPDGHRVAVAVFARG -GR----DRQPVIAAVARVIYDRf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium GWA2_34_9 TaxID=1801604 RepID=A0A1F6PJI3_9BACT ---KLTNQLKYLAAAYQLNAGIFVWDYNTGGYV-DINGDGVFPTASIIKLPVLFQVFRRAE -KGLINLNDKISLTNYYITGGSGALQYSPGRKLTYRQLASLMIQESDNTATNMLLSSVGGM -NELDREIKSWGLKTTSLSNWLPDLDGT------NVSTPKEMGTLLYNIGNTNLLSIKTRA -EIVDIMSHVRN-RNLIQAGLPADVGFIHKTGDIGT-MLGDAGVVALPDGRKYVIVIMVKR -PWNS-FAAKEFIIEASKITYNSy ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 210A TaxID=2014529 RepID=A0A235ICB1_9NOSO -----TSQIRTLLASYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLKVGESGIMQYKPGTKFSVLETATLMMTISDNTATNLVLDRLGGA -TKVSQRFRSWGLQNTALRNLLPDIGGT------NTTSSKDLVRLAALVSNNRLLSPSSRD -RVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] Beta-lactamase n=3 Tax=Erythrobacter TaxID=1041 RepID=A0A165QDN7_9SPHN ----LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD -AGKWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP -RAVNKWMQEAGIEGFQLSRDIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A222ERW3_9SPHN ----LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD -AGKWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP -RAVNKWMQEAGIEGFQLSRDIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc sphaeroides CCNUC1 TaxID=2653204 RepID=A0A5P8VUR0_9NOSO -----TSQIRTLLASYTLNPGIFFLDLATGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLRVGEAGTMKKPIGTKFSVLQTATLMMTISDNTATNLILDRLGGA -AKVSQRFRSWGLQNTAMQNLLPDIPGK------NTTSSKDLVRLAALVYNNRLLSPNSRN -QVLGIMRRVKT-NTLLPAGIGKGATIAHKTGTLRF-IIGDAGIIQMPNGKSYLAGVLVQR -PNHD-PKAGDFVRELSRRVYNY- ->[subseq from] Beta-lactamase n=1 Tax=Cylindrospermum sp. NIES-4074 TaxID=2005457 RepID=A0A1Z4QRN8_9NOST ----LEPQIKALMSRYSLQTGMFFLDLDNGNYL-DIGGDRVFPAASTIKLPILVAFFQDLD -AGKVSLNKQLTMRGDLVASGSGIMQERVGKKYTALETITKMIVISDNTATNMIIDYLGGT -ARLNQRFRTWGLKNTVIRNLLGDFRGT------NTTSSRDMARVLALLVNDKLVSSQSKE -QALDILRQTKT-RTLLPAGLGKDALISHKTGDIGF-LIGDAGFITMPNGKHYLAAIYVKR -PYKD-VRGRNFIRQVSQLVYNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I4CU21_9BACL ----WQQVIQETLIDAPGVFGVAATHLETGETA-GNLENELFQLASAFKIPILVTLMRDVE -AGKITLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNFATDLILQLV-GL -DNVNAHMRELGFSQIHLRHNCWQLLNSQGTLENNVATPAELNRLLVMIGKKEILTPASCD -LMLDILRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPDNKGAIAVTVLSR -GIKDKQAAELTIAKVAKAVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A2D8MAT4_9SPHN ----LGQRISQLAEGSQGRIGVYAIDLTTGHEI-GVLADQRFPMASTSKVAIAATYLAGVD -AGKWSLTSEWRLPR-------------PGGALSGKQHLDLMISKSCNACTDALLNAVGGP -KAVNDWMRSAGITEFQLTRDIATLVRASAVDFRDSATPRAMGQLLAGIYQGKWLSASSRG -VLMNAMRATTTGKKRMRSALPTSAGLAHKTGTLAR-TASDIGIFHTPDGRAVAVAIYVTG -QSPSMAV---------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. An22 TaxID=1965590 RepID=A0A1Y4GQL6_9BACT ---AARQQIETLLQDKKATVGVACSI--DGDDF-ALNDTVRYPLMSVFKLHVAVAALQRME -AEGTRLDEALTIDSTQMHRYSPLLGLYPSGNISYTDLLHYALALSDNNACDILIDYAGGI -GAIKHCIDRAGITGYDLAETEASMHADIPACYRNWAHPSSVVQLLQKILDGSLLNEEHTR -FMRTTLVETSTGLNKIRAGLPPEIVLGHKTGSSGTIADNDASFFCLPDGRLCFLVVLVKD -SRESETTNAALIARIARIVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf412 TaxID=1736370 RepID=A0A0T0Q060_9SPHN ----LQYRVDQLLRQFPGKAGAAIVAVDEGWSV-SSGGTLSLPQQSVSKLWVAMTVLAQRD -AGRLRLDDPVVVTRDDLTLHQPIASLVRGDGTTVGALMTRALTQSDNTANDRLLTFVGGP -SAVRAFIAEKRLGAIRFGPGERLLQARYVDNPPDGAAPLAIADALARLARGELLSETSTR -LLLETMGASRTGRARLKAATPAGWELAHKTGTGQNAGFNDVGLVTAPDGRRYGIAVMIGD -TTAPMRTRQFLIQNVASAL---- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=UPI0010432A98 ----LLNAVQALGGAFRGQVGISVRDIDEGWTV-AWGGDSARPQQSVSKLWVAIAVMAAVD -AGKLSLDDAITVRRSDLTLHQPIRAKVGAAGTTIGELLRGAMTHSDNTCNDVLLWRVGGP -IAVRRLLRDKGIEGVTFGPGERLLQARYLAAPYDGASANGITLGLSLLAQGKLLSARSTA -SLLALMRQSRTGPLRLRSGLRPGWTLAHKTGTGQATGYNDVGLIVAPDGHRYAVAVLIAS -TREPIPVRMRLMGDVTRALVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Root241 TaxID=1736501 RepID=A0A0Q8XN82_9SPHN ----LVTSLDGITRNFNGLVGVAVTSIEDGWTAsNVTASRPLPQQSVSKLWVTMTVLDAVD -RGVLRLDDPLTITRADFTLHQPVAALVKGDASTVGEIMRRAMQMSDNTCNDKLLHLVGGP -QAVRDFIARKQLGTIRFGPGEKLLQAAYVKDPPDGAAPASIANALARLYRGELLSANSTA -WLLATMDGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAVAVMIGD -TSRPIRERQLLMQAVARAIVAH- ->[subseq from] Beta-lactamase n=1 Tax=Rippkaea orientalis (strain PCC 8801) TaxID=41431 RepID=B7JVX1_RIPO1 ----LKAKLDKIATQSKLKPQAWFMDLDNGAYV-SVNGSVPVPAASTIKIPVLVAFFEALD -AGKIHLDEILIMDKAIITSGAGNMQYPPGTKFTALETATQMIVISDNTATDMLIRRLGGK -EALNARFRDWGMTNTVINNRLPDLEGT------NTTTPEDLSKLLARIERGEVLTLRSRD -RLLGIMQETRT-RTLLPQGLEKDAIISHKTGDIGS-IIGDAGIIDIPNGKRYIGAVFTSR -PYND-PMGRALIQDFSRTTYQHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Cytophagaceae bacterium TaxID=2026729 RepID=A0A4Q3NX30_9BACT ---RLTQELMRLSDMSGGKVGICATHIETGKTI-TQNGKEGFPMASSYKVAIATQLLTRVD -SGSLTLAQLIPITKDDFHPGSGMLPNSPNSDLSVRSLLEFMLLISDNSATDICLRLAGGP -AAVNACMKRMGIEGLRVDRPTAWLIAAFEKDPRDTSTPEAMTLLLTKLYTQPVLKPASQA -LILDIMKRCETGLARLKGALPPDTEVLHKTGTIGL-TASDVGIIILPGN----------- ------------------------ ->[subseq from] HGE-1 beta-lactamase n=1 Tax=Brachyspira sp. CAG:484 TaxID=1262759 RepID=R5HGE6_9SPIR ----LSFKLRRYTWQKDYRIGIAVLKNDKIWTI----GTQKQPLLSVFKYFIAVEVLNKLN -KQKIDLNTKLTIKETMINKYSPMLKKYKSFPITIAELLEYTISESDNNASDILLEYIGGA -RKLDKVLKDTGFSGIEISVNEKEMNSDINKQYLNQATPKDVAKYMKTVRETDILTVEHKN -FLDKIMEKTVTGEDKIKKGLPPGTVFGHKTGSSSRDADNDAGYVILPNGETYYIAVFISN -SKLSDKENAEIIANISKTVYKH- ->[subseq from] serine hydrolase n=1 Tax=Sciscionella marina TaxID=508770 RepID=UPI000369F9CB ----LRARLAAIAHTTEAQVGVSVQNLAAGQRI-EFRARTRMPSASVIKLPILAELLRMAE -RGELSLAERVRVDRSDVVGGTGQLQEKLPQDVSLHRLARYMIIYSDNTATNLLIDRI-GF -GPVNALIRSLGLHATVLQRKMMDTEAQ-QHGKENYLDAADIAKLLRALWDGRLLAGPARA -IALGFLRDQRL-NELIPAALPPGAPVAHKTGTLDDLVTHDAGYYLVPGSE--VLVVFTTR -GT--TAAGTDAVHRMARAVWD-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium TaxID=165695 RepID=UPI000E72EFF1 -------VVRNLGQSFRGKVGIAVRRIGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPTAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRGFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR -LLLSIMSEAKTGPQRIKGGVPPGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVGIPERWALMQAVAKAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter zhengii TaxID=2307003 RepID=A0A418NQ63_9SPHN --eELSETITGIAEEFGGTMGIAVVDVDTGWST-GYNENDWLPQQSVSKTWVTLTALTMAE -KGLLDLDAPIRVSREDLTLHQPMRKEILRDGTTVGELIERAIQQSDNTANNAILQRVGGP -RAVRAMLREQGLDGIRFGPGEKPMQSSYLDDPVDGAKPIGIARALAAVERGEVLSKERAE -ELLTIMSNTRSGPRRLKGGRADGWVVSHKTGTGQQSGYNDVGVLFAPDSSAYAVAVMIGV -TKRPTIERMQMMQQVTRAVIA-- ->[subseq from] BlaZ n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A0A0R1G2_STAAU ------------------------------------------------------------- -----------HINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Parabacteroides sp. CH2-D42-20 TaxID=2320086 RepID=A0A3L7Z8N4_9BACT ---TIENALQEYIKGKDARIGVAVI-INGKDTA-SVNGNRDFPMMSVVKFPLALTVAHWID -TNGMSLNDSITFRKNDLNEYSPMLKKYGKSRMTIRELLEWSLIESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium 13_1_20CM_4_56_7 TaxID=1803434 RepID=A0A1Q7V8I0_9BACT --qKLESSIREVDHNLDGVLGVAIEDLTTGQKF-FLHEDELFPQASSIKIAVLAELYHQAQ -SGKAKLSDLYTISSSDLVPDSDIMLGLTPSVITNRDLATMMVAVSDNSATNVLIDRV-GM -ENVNALMDSLGLTHTRLRRKMMDVKAA-GEGRENISTPREMMSLLEQIYRGKVLNKEMAA -DFLKMLSTHKQ--SFIPRDLPDGVRTANKPGELE-GVRNDSGIVFAQNR-PYVICVMTTY -LH-TEHDGEDAIARISSAAYRMf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf10 TaxID=1735676 RepID=A0A0Q4DM65_9SPHN ---DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -RGRLSLADPVTVTRADLTLHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP -AAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGLTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRLPIPARMRLMGDVTRAVIA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5M9S3_9BACT ---DFANRILSVEERTGARIGVAALDTASGKRL-DYRSEERFPMCSTFKFLAAAAVLKRVD -EKQDQLDRFIRYAAKDILEHAPVTKAHLVDGMTLGALCAAAIEQSDNTAGNLLLDAIDGR -AGLTNFARNLGDNVTRLDRKEPELNSAIPGDERDTTSSAAMC------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. Leaf26 TaxID=1735693 RepID=A0A0Q4IQL2_9SPHN -------VVRNLGQSFRGKVGIAVRRVGADWTV-AWNGTSLFPQQSVSKLWVSMTFLDAVD -RGKLRITDTTTITRNDLTLHQPSAALVAQNGTSYSDLMRRAMTQSDNTANDTLLRAVGGP -EAVRSFLARRMIKDIRFGPGERLLQSNYLASPPDGAAPSSIVQALAKLKQNDMLSPASSR -LLLSIMSEAKTGPQRIKGGVPHGWSYLHKTGTGQSTGFNDIGIMTAPDGTSYAVAVMIGS -TTVAIPERWALMQAVAKAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. C11 TaxID=1178594 RepID=UPI00140D20EC ---SLQAQLEDIVKDANGTFGVYVKHLETGETA-SIYENRLFQAASTFKVPILSALYREAK -KGTVNLDERVKLTEKDFVPGSGIFQRLTPGVVTIKDLAMMMIIVSDNAGTDKILEII-GK -ETVDQFMKELGLTNIHTPLTCWELLCFQESIHNNVSSPKDMAKLLELIVTKQLISEKACD -EMFDILSKQQH-RNRIPYLLPGNTVVAHKTGTVGS-VINDVGIVKLPYQGTYVITVFSTG -NS-SEAEGANIINKLSKAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BDB0_9BACT --kKLETRVEEIAARLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ -KGKAKLNELYTFDPKDLVEDSQIMAGLTAGMVTNRDLAQFVVAVSDNTATNVLIDRV-GM -QNVNATLRNLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNKELTD -QLIKQLKTLKK-DSYLSYELPTGVDIADKPGSLE-GVRNDSGIIFAQNR-PFAISVMTAY -DR-DEKAAERAISEVALEAYHYf ->[subseq from] serine hydrolase n=1 Tax=Leptolyngbya ohadii TaxID=1962290 RepID=UPI000B59E501 ----LVARIQPLTKDLDLTPGVFLADLDNGNYY-SLNGTATFAAASTIKVPLLIAFFQDVD -AGKIRLDETMIMLQNDVAGGSGDMQFEVGTEFSALEVATNMIVISDNTATNMVIRRLGGI -EAVNQRFKEWGLEQTIVRNLLPDLEGT------NTTSPKELAAVMSLLSQGELLSLKSRD -RAIEIMQGTLT-DTLLPTSIGPGATIAHKTGDIGS-LVGDTGLIDMPSGRRYAITAMVKR -PHND-DRAQELIRQIAATAYDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf30 TaxID=1736213 RepID=A0A0Q4K1W5_9SPHN ------NAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQISLSDRVTLTRADLTLHQPIRALIGADGTTIDELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A497L7A8_9ARCH ----LLERIREAAEGFEGVLGVSVKHLGTGEAA-SLNGGELFPTASVFKVPVIVALYRQVD -AGAVSLDEKVVLREEDKVPGSGILKELSPGLITLRDLVTLMMIVSDNTATDLVVERV-GL -ENVNATLQRLGLERTRVVADCRDILFSLGVENNDVTTPDEMLRLLEMIVEGEAASRESCD -AILETMSRCQTGSYRIGKYLPEKMEIAHKTGSLP-GIRNDAGVVTLDSGERYIISCFT-- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI0014477E96 ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -GGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSAAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=A0A147IWE2_9SPHN ---DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -QGRLSLADPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP -VAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPARMRLMGDVTRAVIA-- ->[subseq from] Beta-lactamase n=3 Tax=unclassified Citromicrobium TaxID=2630544 RepID=A0A0P6ZSV2_9SPHN ---SFERQVAALADGSQGRIGVYAVDLTTGAEV-GVLADQRFPMASTSKVAIAATFLAGVD -QGRWSLSSEFELPG-------------RGTYISAREHLNLMITRSCNDCTDALLNAVGGP -QAVNAWMRSAGILDFQLTRNIAALVRATEIDLRDSATPRAMGQLLAGIYQGRWLSPSSRQ -VLMNAMGDTVTGKRRMTSALPMSANLAHKTGTLSR-TASDIGIFYTPDGRPIAAAIYVTG -QSASMAVEN-------------- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9N7V9_9BACT --qKLESSIREVDHNLDGVLGVAIEDLTTGQKF-FLHEDELFPQASSIKIAVLAELYHQAQ -SGKAKLSDLYTISSSDLVPDSDIMLGLTPSVITNRDLATMMVAVSDNSATNVLIDRV-GM -ENVNALMDSLGLTHTRLRRKMMDVKAA-GEGRENISTPREMMSLLEQIYRGKVLNKEMAA -DFLKMLSTHKQ--SFIPRDLPDGVRTANKPGELE-GVRNDSGIVFAQNR-PYVICVMTTY -LH-TEHDGEDAIARISSAAYRMf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia fonticola TaxID=47917 RepID=U6A6K4_SERFO ---------------------------------------------------AVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDERDTSSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520J9Z6_SPHSX -----VNAISELQSGFQGKAGIAIRAVDDGWTV-EAGGRQLLPQQSVSKLWDAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. WG TaxID=1592629 RepID=UPI0002EAD03A ---ALLNAVQALGAEFDGQVAISVRDIDRGWMV-AWNGERAFPQQSVSKLWVAIAVFDAID -AKRLSLTTPVTVTRADLTVHQPIRALVGANGTTVGALLQCALTRSDNTCNDVLLWKVGGP -AAIRRMLADKGVRGVSFGPGERELQARYLADPYDGASANGITLGLSLLGQQKLLSPASTD -RLLSIMLASKTGPLRLKSGLRPGWKLAHKTGTGQATGYNDVGLLTAPNGHRYAVAVLIAS -TRRPIPVRMQLMGDVTRAIIR-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009E704EE ---DLLNAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQMALSDRVTLTRADLTLHQPIRALIGADGTTIEELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf412 TaxID=1736370 RepID=UPI0009EAA8B5 ----LQYRVDQLLRQFPGKAGAAIVAVDEGWSV-SSGGTLSLPQQSVSKLWVAMTVLAQRD -AGRLRLDDPVVVTRDDLTLHQPIASLVRGDGTTVGALMTRALTQSDNTANDRLLTFVGGP -SAVRAFIAEKRLGAIRFGPGERLLQARYVDNPPDGAAPLAIADALARLARGELLSETSTR -LLLETMGASRTGRARLKAATPAGWELAHKTGTGQNAGFNDVGLVTAPDGRRYGIAVMIGD -TTAPMRTRQFLIQNVASAL---- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=2 Tax=Sphingomonas mucosissima TaxID=370959 RepID=A0A245ZGU8_9SPHN ---ALEASIGQLVREFSGVAGVAVRAVDDGWTV-EASGRRLLPQQSVSKLWVAMTILDQRD -SGRLRLDDEVSLTPADLTVHQPTAYLVKG-GTTVGDLLFRALTQSDNTANDRLLTLAGGP -SAVRSFIERKQLGDIRFGPGERLLQAAYIDNPPDGAAPLAIADALARLARGELLSETSTR -LLISTLESSKTGRARLKAGAAPGWTLAHKTGTGQNAGFNDVGLLTAPDGRRYSVAVMIGD -TQRPMRDRQQLIQAVAATVT--- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A5P6N7R3_9SPHN ----LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD -AGRWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP -RAVNKWMQEAGIEGFQLSRDIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Uncharacterized protein n=2 Tax=Desertifilum sp. IPPAS B-1220 TaxID=1781255 RepID=A0A1E5QLV1_9CYAN ----LKNSLGAIAQQYNLSPGIFLIDLDTGAYV-DLNGTQTYAAASTIKLPILVAFFQDVD -AGKIRLEEMLVMKPEHIATGAGDLQYQPAGTYSALDVATKMMTISDNTATNMLIERLGGA -EALNQRFRSWGLKITALNNPLPDIEGT------NLTSPQELAQIMAIVNRGDWVQGRSRD -RILDIMGRTET-APLLKSGLGPGARLANKTGTLGV-LLADMGLVDTPTGKHYAIAVMVKR -EFGD-PTAEELIYQVSRAAYQHf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=A0A147ING4_9SPHN ------------------------------------------------------------- --------------------------------RTAAKAMEAMIVRSDNLAADQMFATLGGP -AKVQQWVLSHNISGMRVDRTIAQLLRGHLADIKDVATPFAMVQLLRILDSGTALSSQSRA -YLLGLMRQCRTGTRRIRGLLPAGTLVEDKTGTLD-GITNDVGFITMPDGRRVAIAVFARG -GR----DRQPVIAEVSRMIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. 'hensonii' TaxID=1922337 RepID=A0A1Q8ZBE0_9CYAN ----LQDRIQTLRANYALKSGLFFLDVDTGNYL-DINGNKTFPTASIIKLPILIAFFQDVD -AGKIRLDETLVMRPELIASGSGTMQDLPAWSFSALKTATQMIVISDNTATNMIIHRMGGI -SVLNQRFRSWGLKKTVIRNWLPDLSGT------NTTTAREMVYLLSLLDQRKLLSPQSQD -EALGILRRTKT-RTLLPAGLGTGATIAHKTGDIGF-MLGDAGIIELPNGKRYLGAVLVIR -PYND-IAGRNFIRQVSGTVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A222EUF8_9SPHN --rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGTDERSKQSGYLADPIDGAPPVALVEALTRLQCGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Mal64 TaxID=2527991 RepID=A0A5C5ZJ80_9BACT ---DLEKILRPLLEGHRGVVTAAVKHLGTGESF-THEADRPMPTASLIKLPLMVAAYEAID -RGETALDHKITLREEDKVPGSGVLTPHIGAGITLADAIQLMIAFSDNTATNLVIDQV-GL -GATTELMEGLGLHNTKLNAKVFRRDTSINPEGSGSTTAAEILSLVEMLHARELVSPAASD -AMLERLFACQD-RGKLCRYLPEETRVAHKGGSVS-ASRCDAGLMETPAG-PIALAIFTTD -NEGDENEAELLAGEFGRVVYQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacterium sp. RBIITD TaxID=1550240 RepID=A0A285BET8_9FIRM -----YENIQNLIKSTSGNVGASIKNLKTGETI-NINENLVFPSASTIKIVIMAEILRKVK -EGFIRLNDNIILSNFMKTGGSGILHELNSGHFTIEELITLMIIISDNTATNILIDIA-DM -KNVNNMAVSLGMSHTKLQRKMMDFEAA-RCGKENYTCAADMTHILELINDGKVINKEYSN -MMLDILKRQQD-LGRLDLYLPENTIIAHKPGELDF-LEHDVGIVYLKNCT-YIISVLTNK -MKT-NLEGRKTIGKISKMVYDEy ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas viridiflava TaxID=33069 RepID=UPI0013DFD2BA ------------------------------------------------------------- ---------------------------------------------SDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGVRGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. TaxID=1872480 RepID=A0A2E1Y9H1_9SPHN ----LGQRISQLAEGSQGRIGVYAIDLTTGHEI-GVLADQRFPMASTSKVAIAATYLAGVD -AGKWSLTSEWRLPR-------------PGGALSGKQHLDLMISKSCNACTDALLNAVGGP -KAVNDWMRSAGITEFQLTRDIATLVRASAVDFRDSATPRAMGQLLAGIYQGKWLSTSSRG -VLMNAMRATTTGKKRMRSALPTSAGLAHKTGTLAR-TASDIGIFHTPDGRAVAVAIYVTG -QSPSMAV---------------- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=UPI00102E8DA9 ----TRQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGIDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Aphanothece sacrum FPU1 TaxID=1920663 RepID=A0A401IJY6_APHSA ---NLKTKLQAIAAKYKVKPQAWFLDLDNGAYI-NLGGSTPIPAASTIKIPVLVAFFEEVD -KGNIHLDQMLIMDKEVITTGSGDMQYQVGKKFTALEVATKMIIISDNTATDMLIRQIGGK -EVLNQRFKEWGLTHTVINNRLPDLEGT------NTTSSEDLGKLLAKVERGDFLSPRSRD -RLLAIMEKTKT-RTLLPQGIEKEANIAHKTGDIGT-ILGDAGIIDIPTGKRYIGVAFAQR -AYND-PAARSLIQEFSRTVYQHf ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter sp. BPTF-M16 TaxID=2169535 RepID=A0A411ZBE0_9SPHN ----LAGQLYRIGEEFDGRVGLAVVDVGRERSM-HHNGNELMPQQSVSKLWVALTALDQAD -RGEFSIEDVTTIRRQDLTLYQPVRSIVLTRGTSYRDLIRRAIIQSDNTANDKVLNAIGGP -DAVRETIVQKGLGAIRFGPGERIMQSSYISDPIDGATPNAIAQALARLARGELLSAGSTR -AFLQWLTEVKSGPNRLKGGIAPGWTIGHKTGTGQQAGYNDVGILTAPNGDQYAVAVLVAR -TAIPLRERMAMMHEVVGAVIDY- ->[subseq from] serine hydrolase n=1 Tax=Aphanizomenonaceae TaxID=1892259 RepID=UPI000C1C6063 -----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK -ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] class A beta-lactamase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI000F63681D ---TASDALAALELRNGGRLGVFALDAGSGRSL-GWREDERFGMCSTFKLLLAATVLDAAR -QGRLDGTAPIHFSDDDLVPHSPVLREHLALGLTAPELARATQLTSDNAAANLLIRKLGGP -EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE -RLREWMVETGTGLARL-------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. AP23 TaxID=499656 RepID=A0A109LUE6_9SPHN ----LERQLAQLADSSNGRIGVYAIDLSTGREI-GVLADQRFPMASTSKVAIAAVFLAGVD -EGRWSLTSEFRLPR-------------PGRVLPAYKHLSLMISKSCNDCTDALLQAVGGP -RAVNKWMRDAGIEGFQLTRDIATLIRAWSVDAKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMRSALPASANLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] serine hydrolase n=1 Tax=Spirulina major TaxID=270636 RepID=UPI000A075430 ----LQTQIDAAIAGYAGHVGLLVVDLDTGDYV-NSNGLESFSAASTIKLPILVAFYQDVD -QGAVSLDESLTMTAELVAAEAGTMKYPVGTQFSALETVTTMITISDNTATNMIIARLGGY -DALNQRFQDWGLQQTEVKQWLPDLGGT------NVMSPVDVVNLLIRLERGELVSLRSRD -RILSTLTAVKN-RQLLPQGLDEKAVIAHKTGTLG-GVLADVGLVDVPNGKRYAIAVITKR -PRHD-PQAQTLIQTLSRLTYQHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=A0A0Q4LFB3_9SPHN ---DLLNAVQALGARFDGQVGISVRDIDENWGV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -RERLSLGDPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMTRSDNTANDVLLWRIGGP -AAVNRMLRDKSVTGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -PLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPVPVRMRLMGDVTRAVIA-- ->[subseq from] Penicillin-binding protein, transpeptidase n=2 Tax=Aphanizomenonaceae TaxID=1892259 RepID=D4TRV4_9CYAN -----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK -ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=UPI000778B4C2 -----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK -ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098EA058 ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNTVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5205 TaxID=2019671 RepID=A0A2N6LUS0_9CYAN ---QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIQLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=UPI000C1BE692 -----KTTIENLSAANNLIPGVFIVDIDSGAYV-DVSGNNNFPAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK -ELLNSRFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15B TaxID=2714943 RepID=UPI001407DDFE ------------------------------------------------------------- ---------------------------------SARSLMASMIIKSNNAATDILLNDLGGP -DTLQDWIEQHRLSGMRVDRTIARLLAAKRDDLRDSSTPMAMLNMLSKLDKGELLRPANKQ -YLLGLMAKCTTGKNRMRALLPAGTRVEHKTGTLN-GLTADVGFITLPDGRRIAVAFFARN -GS----DRPRTIAEAAWTVYYGf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Cra20 TaxID=1327635 RepID=A0A2K8MLD2_9SPHN ------TSIDNITRNFNGLVGVAVTSIDDGWTAsNVTASRPMPQQSVSKLWVAMAVLDAVD -RGTVRLDDPLTITRSDFTLHQPIAALVKGDATTVGEIMRRAMQLSDNTCNDKLLRLVGGP -QAVRDFIYRKQLGTIRFGPGERLLQAAYVKDPPDGAAAASIADALARLHRGELLSASSTN -WLLATMGGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAVAVMIGD -TSRPIRERQLLMQAVGSAIVAH- ->[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium SG_bin6 TaxID=1827383 RepID=A0A1W9HKW6_9PROT ----LQNSVQLLVRQFQGKVGAAVASVDQGWLL-SANGDVRLPQQSVSKLWVAMTVLDGID -AGRFTLDTPMKVTREDLTLHQPIAAMKPGQGTTVGDLLQRALTQSDNTANDRLLRFVGGP -EAVRGFIARKALGNIRFGPGERLLQAAYVADPPDGAAPAAIATALSRLKQGELLRPFTTG -YLIATMESSKTGRMRLRGAVPLGWSFGHKTGTGQTAGYNDVGILTAPDGRSYTLAVMIGD -TRRPIAERQALMQQVVASIIAY- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. HI00D59 TaxID=1822215 RepID=UPI0012E8735A --rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRSADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGTDERSKQSGYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPENWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEKMQQVVRAVAR-- ->[subseq from] Uncharacterized protein n=1 Tax=Chondrocystis sp. NIES-4102 TaxID=2005460 RepID=A0A1Z4RVV9_9CHRO -----KLKLQELGQQYSLKPEVFIADLDTKGFV-NLEASNAIASASTIKLPILVAFFQDVD -AGKISLSEKLTITKEDVATGSGDLQHKPGTKLSALETAEKMMVISDNTATNMLIKRLGGQ -ESLNQRFTKLGLTATKIRNPLPDLDGT------NTTTPEDLGNLLINISNGELVSLRSRD -RLLGIMRNIVR-DTLLPQGLEPGAIIAHKTGDIAS-VLGDVGMIDMPNGKRYIAAILVKR -PTNS-FEAQEFIQKASRLTYQHf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus centrosporus TaxID=54910 RepID=UPI000F09BDF6 ----WQQVIQETLIDAPGVFGVAATHLETGETA-GNLENELFQLASAFKIPILVTLMRDVE -AGKITLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNFATDLILQLV-GL -DNVNAHMRELGFSQIHLRHNCWQLLNSQGTLENNVATPAELNRLLVMIGKKEILTPASCD -LMLDILRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPDNKGAIAVTVLSR -GIKDKQAAELTIAKVAKAVYD-- ->[subseq from] class A beta-lactamase n=1 Tax=Sphingobium abikonense TaxID=86193 RepID=UPI00078840FE ------SVIRNLGQSFKGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTLTRNDLTLHQPSAALVAKQGTSYSDLMRRAMTQSDNTCNDALLRAAGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLSNPPDGAAPGSIVAALAKLKQGDMLSPASTR -LLLNIMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVPIPERWALMQAVSKAVAA-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1JDM0_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIKG------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A353BXE9_9FIRM ----------QAIDFQKLNCAFVVKNLQTGECA-SYNSEARVASASLIKLAVMAESIRQVK -EGKLNLKQRLVVREEDKVDFSILTLLATGNSYTLRDLLTLTIVQSDNTAANILIDLT-GM -TEINKFCNDLGLKDTVLRRKMMDGEA-RKAGRENYTTAADMARFLELLYQGKLLDPESCS -LMIEIMKKQLD-NTMIRLYIPDDTVVAHKTGELE-GISHEAGIVYHDKA-DFIIVMLVWD -AL-SGNDARQTIGRAAKTVYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_53_38 TaxID=1797961 RepID=A0A1F9XR82_9BACT ---TMVTALENIAYNYNGHVGIYIKDLNSDKVW-EYNPDRLFPSASLIKVPIMIAICEKIK -RGELSLDTQIKLTRRDRAGGSGSLKWVREGTLSVTEIIYKMITESDNTATKMLVEYG-GI -NYFQQAFENLGLVYTKIYPEGLSLTSS-RVVRENYTTAREMAGLMERIYKGEMVDRSLSE -FMLDVLKHNKS-RSRLRKGLPIGWEIGHKTGLLRR-SCHDVGIVFSPRGD-YLIAVLTSD -VP-DYTSAKGFISRVAKLTYEYy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI000684E963 ---ALQQRVTQLIRSFPGKAGAAIQAVDEDWIV-SEGGALYLPQQSVSKLWVAMTVLGQRD -AGRLKLDDPVLVTRDDLTLHQPIAGLVTGEGTTVTGLLTRALTQSDNTANDRLLTYVGGP -AAVRRFLAEKHISGIRFGPGERLLQSRYIDNPPDGAQPAAIVEALARLARGELLSETSTR -VLLDTMANSHTGRARLKAATPAGWTLAHKTGTGQNAGFNDIGILTAPDGRRYAIAVQIGD -TTAPMRVRQVLIQQVAAAL---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V594_9BACT -------------------------------------------------VMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSLRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASILTGLPASWVV---------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009906A7A ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium CG2_30_44_21 TaxID=1805292 RepID=A0A1J5H0R9_9CYAN ------AKIKELAAQKDLAMQMMAIDLDSGTYV-QVGANQKIAAASTIKMPLLVAFFQDVD -AGKIKLDEMLEISEDVVVGEAGFQGLALGTKKTALETATQMIVISDNTATNMIIKRLGGV -ATVNQRFKSWGLKNIVANNKLPDLEGT------NTISTQDMVTLLAMVDQGKLVTPRSRD -RFMDIMSRPIT-NTLLPQGIGAEARIVHKTGDIGS-AVGDAGIVDMPNGKRYAIAVMVTR -PNND-QRANELIRQISRASYDYf ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HI00D59 TaxID=1822215 RepID=A0A165SA22_9SPHN --rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRSADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGTDERSKQSGYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPENWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEKMQQVVRAVAR-- ->[subseq from] serine hydrolase n=1 Tax=Chondrocystis sp. NIES-4102 TaxID=2005460 RepID=UPI000BBCB999 -----KLKLQELGQQYSLKPEVFIADLDTKGFV-NLEASNAIASASTIKLPILVAFFQDVD -AGKISLSEKLTITKEDVATGSGDLQHKPGTKLSALETAEKMMVISDNTATNMLIKRLGGQ -ESLNQRFTKLGLTATKIRNPLPDLDGT------NTTTPEDLGNLLINISNGELVSLRSRD -RLLGIMRNIVR-DTLLPQGLEPGAIIAHKTGDIAS-VLGDVGMIDMPNGKRYIAAILVKR -PTNS-FEAQEFIQKASRLTYQHf ->[subseq from] Beta-lactamase n=1 Tax=Rhodanobacter thiooxydans TaxID=416169 RepID=A0A154QFZ0_9GAMM ------------------------LDLRSGEAW-RVNARQAFPMMSVFKAPVAGAVLDRIE -HGGLSMELTVVIRRRELSSGT-IRDHFEGERFTVRQLLADAVSRSDNTAVDALLDTIGGP -RVVTAFLRSRGIDGMRVDLGERDFQSAYLVDPRNRSTPDAAAQFLRKLWEGQLLPPEPTR -HLLDLMYAQTT-PSRLRLGLPPGARLADKCGTSYTAAYNDIGILSWPDGHAIVVAAFLTA -SVDPKGERDALFADLARTVAA-- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000FA20573 ------------------------------------------------------------- --------------------------------------CSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNR------------- ->[subseq from] serine hydrolase n=1 Tax=Geminocystis sp. NIES-3709 TaxID=1617448 RepID=UPI0011875654 ---DLKNKFIQLKTKYNLEPGAFFVDLDNGSFV-NFNGTTTFSAASTIKIPILVAFFQDVD -AGKIYLDEQLATSAKNIGSGSGGMQYQPGTKYTAIHTATEMIINSDNTATNMIIERLGGK -DELNKRFKEWGLDVTLINNSLPDLEGT------NTTSPKDLAITLAKVNQGELISLRSRD -RLLDIMRQTRT-RTLLPQGIEKDATIAHKTGDIGT-ILGDAGIVDIPTGKRYIGGVLVKR -PYND-YSARTLIQEISRTAYQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Geosporobacter subterraneus DSM 17957 TaxID=1121919 RepID=A0A1M6H6Q8_9CLOT -----EKGIRMLLGNTMAKTCVVLKDLRKDEWIfRKDETMVVPSASTIKILIMVEALKQVQ -EGKYQLDERFSIMEEDKVDYSIL-SDLTTDSYTFRDLIMLMIIVSDNTATNVLIDLL-GF -DAVNHRAMEIGLQNTRLQRKMMDFEAA-KAGKQNLTTAMDMALLMEKIYKKEVLNLDLCN -LALDILKRQKD-KTMLKRYIPEDVEIAHKTGDLTN-LNHDIGIIFLPQST-YLLGVFVSE -AK-SNLEAQQTIGEISKTVYDYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. Ant20 TaxID=104605 RepID=A0A0A6CXG7_9SPHN ------NAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQISLSDRVTLTRADLTLHQPIRTLIGPDGTTIDELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] Uncharacterized protein n=2 Tax=Tuwongella immobilis TaxID=692036 RepID=A0A6C2YMI9_9BACT ---ALAEKLKPLIAAHQGTVAIGVQHLGTGATV-WHNADEVMPTASLIKLPIMVEVYHQVA -EKKLSLDDRIQLTKEDMVPGSGILTANFSEGFPLRDAVTLMIVFSDNTATNLVLDKI-GI -PSTNFRMAKYGMPNTRVNAKVFRGSKRTKQYGLGSTTAREMITLLHLLHQKKLVSAAACD -AMLATLRRCDD-DEKFPRFLPASVKVAHKTGSVSD-ARTDAGILEFPQG-PVAICVLTAK -NRKADNAGNRLCADVAKVVYQHy ->[subseq from] serine hydrolase n=1 Tax=Allonocardiopsis opalescens TaxID=1144618 RepID=UPI000D049318 --------LVALEERTGRTVGAVLLE--GGRRLvAHRPDQVMPTCSVFKSFLVAALLHDRD -DREYWYDAAIDYDESDVVINSAVLSERSG-PISPHDLAEAALRYSDNTAANLLLAELGGP -AVLTEFTRSLGAAVTRFDRLEPELNAAVPGDDRDTSTPAEVAMLMHAVLVERSAGAYTAA -RLNTWMLWNET--SRITEALRTGDELTDRTGAGAYGVVNDAGVLYRPGQPPRSFAVMTRT -DDEDAENDDAVVLEAARLL---- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A350D3C0_9BACT ---KLISDLRSFSDQLDGVLGLAIKDLSTGRTI-FINENEIFPQASSIKMTILLEVLKQAE -EGKLKLDEFINLTPEAKVGGGLILAYYPALKISIRDLCVLMVVLSDNTATNLLIDRA-GL -KNINNRLQGLGLNQTKLQRKMMDVKAA-GEGRENLSTPLEMMSLLEKIYKGSVLSPASKQ -EFFNILSLPKD--SPLQQAVPEGVVVADKPGELE-AVRCNSGLVFLKKH-PYVICVMTTY -LK-NEAEGNATIKKIGQAAFSYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9LUK5_9BACT -haKLEAGLLREAEGLDGVMGYFIQDLATGETF-EHNAELVFPTASTIKLTVLLELMRQDQ -EGKLSLDEKHTVRRNETAAGDPILYMLGDGTMTLADLATFMVVLSDNSATNILIERV-GM -ANVNSRAGSLGLNQTHLRRKMMDLEAA-RQGNENVSTPRELSGLLAKLRAGKALDPAHTK -KYLALLALPK--DSLFNKALPSGTVIEDKPGALE-GVRCDAGIIEIPGR-PFVITVMTTY -LG-DENQGERAIESVARKAYEHf ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00117CA2AF ------HMIRQLLQETPYNVHMIVKDLRTDETFiCERPDAVFSSASLIKVPILLAVLHHVQ -SNQGSLHQVLTITPEDWVDFSGISEQQLVS-TTIYELLVWMIITSDNTATNVLINYI-GM -DALNRYFREIGLTHTILQRKMMDFER-LANGVDNVTTTRDMAHIFTHIYRQDLLMPSFSA -LAIDILSRQRV-HDLLRRYLVDDVRIAHKTGGLD-AVDHDVGIVYGDSKD-YLIGVFVTE -VTNN-QDARQLIGRISKVVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Chryseobacterium nematophagum TaxID=2305228 RepID=A0A3M7TLR1_9FLAO ---QLQEKIKHIIYTAGGKIGVGVKGMDFKTGF-VINGNHEYPMMSVFKFPIAFAVLDKVD -KGELKLNQKFHMPKESLDTYSPMIKDFPNQDVTLADLLMYMVTKSDNNACDFLITKVGGP -AAINKYLHRAGVKDIAIAYTEGAMEKEKSLQYKNWLKPGGSLQLLQLLFDQKLLSKSNND -FLFQIMRELPDGSKRITVQLPAETELFHKTGYSGMAAFNDMGIVTLPNGKHLAISVFLSD -FQGPLDRGINVIAAISKEIWDFy ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. CHR27 TaxID=2506423 RepID=A0A4Q1KEZ1_9SPHN ---ALRVQIETLGSSFNGTVAISVRPVDADWEA-AYNADSLMPQQSVSKLWVAMAALDAVD -RGKLTLLDPVTVRPDDLTLHQPLAAMVRSTGTDVADLMTRAMTESDNTANDVVLRQIGGP -EAIRGYLARRFLANIRFGPGERVLQSDYLANPMDGAAASSITLALARLKRGEMLSPASTA -YLLAVMHEAKTGRQRIKGGVPAGWSYAHKTGTGQATGFNDVGIMTAPDGTSYAVAVMIAS -TTVSIPERWAVMQGVARAVAAY- ->[subseq from] Serine hydrolase n=1 Tax=Erythrobacter sp. HN-E23 TaxID=2488860 RepID=A0A3N5DT47_9SPHN ---DLAQTIDSLGEDFGGLLGIAVEDVDAGWTT-AYNGERMLPQQSVSKFWVSLTALDQAD -RGELDLDRTIVLTRKDLTLHQPIRAEILLRGTTPRELMEQALTHSDNTANNAILEAVGGP -AAVSTMMARHDITGVRFGTDEITKQSAYLDDPIDGATPLGMVHALSRLARGELLSERSTR -LMIETLKRTHSGPRRLRGGREGDWVVAHKTGTGQQSGYNDVGLVISPGGRTYAVAVLIGW -TRRPTIERMAMMQKVTRAVI--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudanabaena sp. PCC 7367 TaxID=82654 RepID=K9SF80_9CYAN ---ELKAQINQLTAAEDLGLQALLVNIDTESYV-NINADVPIAAASTIKLPLLVAFLQDVD -AGKIRLDEQLEISEDVRVGHAGELQYEPGTTVSALETITLMITISDNTATNMVIKRLGGA -GAVNERFASWGLNATVIRNPLPDLEGT------NTTSPQDLVNLLAMVDQGKLIAPRSRD -RFMDITRRTLT-DTLLPQGIGPEARIAHKTGDIAS-VVGDAGIIDMPNGRRYIMAALVQR -PDND-QRANDLIRQVSDATYQHf ->[subseq from] serine hydrolase n=1 Tax=Citreicella sp. 357 TaxID=766499 RepID=UPI0009FF7783 ------------------------------------------------------------- --------------------------------------CSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNPL------------ ->[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. MDT14b TaxID=1710886 RepID=A0A1B7W8E0_9NOST ------NSLQTLTANSDLIPGVFLLDLDNGGYI-DINSNISFAAASTIKIPILIAFFQDVD -GGKIRLDEMLILQKEMIVGGSGNMQYQPTGSYTALDVATKMITISDNTATNMLVAKLGGQ -EALNGRFRSWGLITTMIRNPLPDLEGT------NTTSPRELGNLISMVNQGNMVSMRSRD -LILNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVKR -PNND-PRAAKLISSISSTAYQHf ->[subseq from] Beta-lactamase n=1 Tax=Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437) TaxID=111780 RepID=K9XQQ8_STAC7 ---SLKSKLQTLASQYKLQPAIFLVDLDDHSYV-SIQGSGAIAAASTIKIPILVAFFQDVD -QGKFRLDQELTMNKEDIGSGSGSMQEKPGTQFTTLEVATKMITISDNTATNMLIKIMGGA -EKLNQRFLEWGLTETVIRNPLPDLEGT------NSTTPEDLGNLLINLERGKLVSLKSRD -RMFTIMSNLVR-NTLLPVGLEADATIAHKTGDIRS-VLGDVGIIDMPNGKRYVASVLVKR -PDND-PQAKEFIQKMSQVAYQH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649UI99_PSEAI ----------------------FAIDTGSGNTF-GYRSDERFPLCSSFKGFLAAAVLERVQ -QKKLDINQKVKYESRDLEYHSPITTKYKGSGMTLGDMASAALQYSDNGATNIIMERLGGP -EGMTKFMRSIGDNEFRLDRWELELNTAIPGDKRDTSTPKAVANSLNKLAFGNVLNAKVKA -IYQNWLKGNTTG------------------------------------------------ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Riemerella anatipestifer TaxID=34085 RepID=J9QX37_RIEAN --nNLKYQIEKIISSKKGDFGISIID-ENNNII-EINGNKSYPLLSTFKFPIALTILHKVE -NGELLMQQQIFIKKEELLEWSPFKEKYPNGNISLEEALHWMIVYSDNNMTDILLRLIGGT -NAVEKFI---DDENFVIKNNEDEMHKDWNSQFINKSTPNSFTKLLKNFSEGKMLNSENTK -WLYESMVNSKTGVKRLKGKLP-NVKIAQRAGTSFTGAINNVGIMQLPNNQKIYITVFIHN -TSEEFNKGEEIIADIAKTTYEFy ->[subseq from] serine hydrolase n=1 Tax=Cronobacter dublinensis TaxID=413497 RepID=UPI00131A1E2E ------------------------------------------------------------- ----------------------------------------------DNTAANLLLTTIGGP -KELTAFLHSMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=A0A4R2PJU1_9SPHN ---ALQARIEQLVRNFPGKAGAAIVAVDEDWVV-QQGGDLSLPQQSVSKTWVAMTVLSQRD -EGRLTLDDPVLVTRDDLTLHQPIAGLVGANGTTVGGLLTRALTQSDNTANDRLLTVVGGP -SAVRRFIAKHQLGAIKFGPGERLLQSRYIDNPPDGAAPVAIAGALARLARGELLSETSTR -ILLDTMAASRTGHARLRAATPPGWKVAHKTGTGQNAGFNDVGLLTAPDGRRYAIAVMIGD -TAAPMRLRQQLIQNVCAAL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Paraburkholderia fungorum TaxID=134537 RepID=A0A1H1JV03_9BURK ------AELQRIIEYSRGSVGVSALHVETGERL-GLHEDCRFPLESTIKIAIAMKVLALVD -AGELALSDWIEVQSSEMNSGGPLGEEFLHDGLSVMNLLEPMITRSCNTSTDVMFRVAGGA -EAVADYVETLGIEGFESRYTMRHALCDYRNDLRDQCTPYTMIELLNALWSGKGITRASRD -LLLDIMSRTTTSPERVKGRLPQGVPFANKTGSGL-GAAADVGFLTLPDGGTVALAVYVKD -SPENMAYRNSIIADVARLAYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Poribacteria bacterium TaxID=2026781 RepID=A0A495Z2Y4_9BACT ------SAIQDFTAHTEGIIGVAAKHLETDKRV-SHNADTIFFTASTLKVPLLVELYRQVD -AGIIDVHQRIDLTDALRVPGSGVLKELAAGLPTIHDLAMLMIIISDNTATDILYNQV-GG -DNINNTMQQLGLTHTHIPMTCRELLYGFSEDRSDVSSPNDMCCLLELIYDGDILSPQSRG -AVLDILKRQQL-STVIPHALPSGTVVAHKTGSYHS-VRCDVGIVFSPTG-PYTVAIMAKQ -MTGDRLSVDASLAAVSRAVYDEf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. WG TaxID=1592629 RepID=A0A0W1QLM6_9SPHN ------NAVQALGAEFDGQVAISVRDIDRGWMV-AWNGERAFPQQSVSKLWVAIAVFDAID -AKRLSLTTPVTVTRADLTVHQPIRALVGANGTTVGALLQCALTRSDNTCNDVLLWKVGGP -AAIRRMLADKGVRGVSFGPGERELQARYLADPYDGASANGITLGLSLLGQQKLLSPASTD -RLLSIMLASKTGPLRLKSGLRPGWKLAHKTGTGQATGYNDVGLLTAPNGHRYAVAVLIAS -TRRPIPVRMQLMGDVTRAIIR-- ->[subseq from] Serine hydrolase n=2 Tax=Hapalosiphonaceae TaxID=1892263 RepID=A0A4D9CLG3_MASLA ---QLNTQIKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLSNNQLLNDGSRS -QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Hapalosiphonaceae cyanobacterium JJU2 TaxID=2109628 RepID=A0A328ICR5_9CYAN ---QLNTQIKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLSNNQLLNDGSRS -QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf226 TaxID=1735691 RepID=A0A0Q4HYU5_9SPHN ------NAVQALGASFKGQVGITVRDIDEGWVV-AWDGDTRRPQQSVSKLWVAIAVMDAVD -RGQMALSDRVTLTRADLTLHQPIRALIGADGTTIEELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLDAKGVEGVTFGPGERVLQARYLAAPYDGASANGVTLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDIGLLVAPNGHRYAVAVMIAS -TREPIPVRMRLMGDVTRAVVA-- ->[subseq from] Beta-lactamase n=1 Tax=Geminocystis sp. NIES-3709 TaxID=1617448 RepID=A0A0D6ARF5_9CHRO ---DLKNKFIQLKTKYNLEPGAFFVDLDNGSFV-NFNGTTTFSAASTIKIPILVAFFQDVD -AGKIYLDEQLATSAKNIGSGSGGMQYQPGTKYTAIHTATEMIINSDNTATNMIIERLGGK -DELNKRFKEWGLDVTLINNSLPDLEGT------NTTSPKDLAITLAKVNQGELISLRSRD -RLLDIMRQTRT-RTLLPQGIEKDATIAHKTGDIGT-ILGDAGIVDIPTGKRYIGGVLVKR -PYND-YSARTLIQEISRTAYQHf ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. Leaf343 TaxID=1736345 RepID=A0A0Q5Q225_9SPHN ---ALQAAVDSLIRGFDGRAGAAVRAVDDGWTV-EAGGRQRLPQQSVSKLWVAITLLDLRD -QGRARLDEPIAVLPADLTLHQPIAYLVAKTGTTVGGLLTRALTQSDNTANDRLLTFVGGS -SAVRAMIAKKRLGDIRFGPGERMLQARYIGDPPDGAAPLAIADALARLARGEILSETSTR -IMLDTMGASVTGRARLRAAIPPGWKISHKTGTGQNAGFNDVGLLTAPDGRRYALAVMIGD -TVRPIRERQQLIQAVAAAVT--- ->[subseq from] Uncharacterized protein n=3 Tax=Alistipes TaxID=239759 RepID=A0A4Y1WLN5_9BACT -------------------------------------------MMSVFKFPVALAVLDRMQ -REGIPLTQPISITPDLLLPYSPMRDSLPAGGLTLGQLLRYTVSESDNIACDILLREAGGP -EAVEAYVRSLGIGGIRIAASEEEMHRGIGNQRVNKARPSSVCTLFDLFLQGRLLKGEYNA -LLQRLLCGTTTGANKLKAGLPAGIVIGHKTGSSDRTADNDAGYVLLPDGRRYCIAVFVTE -SEENDAANAAIAASASRAAYEYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf10 TaxID=1735676 RepID=UPI0012E31BCE ------NAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -RGRLSLADPVTVTRADLTLHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP -AAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGLTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRLPIPARMRLMGDVTRAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus simulans TaxID=1286 RepID=UPI000FEE94AD --------------------GYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQYDLVEYSPVTENHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMP---------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium MED-G03 TaxID=1986231 RepID=A0A2A5YN62_9SPHN ------SVIRNLGQSFRGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTITRNDLTLHQPSAALVARDGTSYSDLMRRAMTQSDNTCNDALLRAAGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPSSIVAALAKLKQGDMLSPASTR -LLLNVMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVPIPERWALMQGVAKAVAA-- ->[subseq from] Penicillin-binding protein n=1 Tax=Fischerella sp. NIES-3754 TaxID=1752063 RepID=A0A0S3TL43_9CYAN ---QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKHPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRY -KTLDIMRRVEN-RSLLPAGLGKGAMIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella major NIES-592 TaxID=210994 RepID=A0A1U7H200_9CYAN ---QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKHPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRY -KTLDIMRRVEN-RSLLPAGLGKGAMIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525KXQ4_9CAUL ---ELQATIAKLAETYREPVGIAVTDVSDRWTA-QVAGSEVFPQQSVSKLWVALTVFQAVD -RHAMTLDQPVVLTPDDRSVYQPLASRIRGPNTTVYDLLRRQLTESDNAANDKLIREVGGG -GAVDRTLAEKGLAGLGVGETERDLQTQYLANPPDGAKPMAITESLAALKRGELLSPGSTE -AMLGLMGEAKTGLSRLRAGLPAGWSIAHKTGTGPSVGINDVGLVTAPDGRSFAVAVMMRE -TRKSVPARLVLFQRISRAIVDYw ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas yabuuchiae TaxID=172044 RepID=UPI0009FECD00 ------NAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -QGRLSLADPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP -VAVNRMLKDKGVAGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPARMRLMGDVTRAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9431 TaxID=1173023 RepID=UPI0003F92417 ---QLNTQIKALMARYKLQPGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLSNNQLLNDGSRS -QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Beta-lactamase n=1 Tax=Hapalosiphon sp. MRB220 TaxID=1704290 RepID=A0A0M0SDU6_9CYAN ---QLNTQIKALMARYKLQPGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLSNNQLLNDGSRS -QALDIMRRVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] hypothetical protein n=1 Tax=Planktothrix serta TaxID=1678310 RepID=UPI0009F932DC ----LKTAILGLAKDSKLKPGVFLVDLDTGNYV-DIQGELPLPAASTIKVPILVSFFQAVD -EGRLRLDEVLTMEEKHIAKGSGELQKPVGSKFTALETATLMITNSDNTATNMIIDRLGGI -ESLNQQFAFWQLKQTQMQNILPDLEGT------NKTSAKDLVTLMAEINQGKLVSVKSRD -FMLRIMQQTRN-RSLLPRGLGEGTFIAHKTGNIDS-VCGDIGLIDMLNGKRYLVGILVER -EA-DDPQANELIRQVSSTIYQYf ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Ji-3-8 TaxID=2708539 RepID=UPI0013EA4BA7 ---KLTADFQPIANRVPGNLGVAVEDLGTGQII-SFNGEKRFPMQGVFKAPLGAAVMAEIE -AKRLKLDDTVLIEDVDLSPPSAIADAWPGRNYTIQELLERAVGQGDNTAADVLMKRVGGP -GAVTAWLQGRKVMHLDVDRYERQIQPAYLADPRDTATPLGALRFLEALNQAELLEPESRR -VLGRITGQTTLAPNRLRAALPDGARLAHVPGTARTDAVNDIGVYTLKDGRKFAVVAFVSG -SALSVADQEKAIADVGRVVIK-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8CUA5_9BACL ----WQQVIQETLIDAPGVFGLAVTHLETGETA-GNLENELFQLASAFKIPILVTLMRDVE -AGKITLDQRVTLKWEERVPGSGILQELDAGALTVKDLATLMTIVSDNFATDLILQLV-GL -DNVNAHMRELGFTQIHLRHNCWQLLNSQGTLENNVATPADLNRLLVMIGKKEILTPASCD -LMLDILRRQHY-NSRLPYLLPPGTKVAHKTGTVNE-VVNDAGIIYLPDNKGAVAVTVLSR -GIKDKQAAELTIAKVAKAVYD-- ->[subseq from] Beta-lactamase, putative n=1 Tax=Leptolyngbya sp. NIES-3755 TaxID=1752064 RepID=A0A0S3U4P8_9CYAN ---------TAIASQTQLTPGFMIVDADTHAYV-DVNGSNPIPAASTIKFPILVAFFQAVD -EGKIRLDEPLTMRKELVATESGELQNLPGSQFPAIEVATKMIDISDNTATNMIIDRLGGK -DAVNQRFQSWGLTNTAVQNMLPDLPGT------NTSSPRDMVALLDAVNRGELVTMRSHD -RMLSIMRKVVN-NSLLPQGLGEGSAIAHKTGDIGI-MLGDVGMIDLPNGKRYLMAAMVKR -PHND-DRAGDLIRQVSKMTFQYf ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. TCA1 TaxID=2682474 RepID=UPI001358A800 ---ALGQQITALGQGFDGDIGIAVEDVQTGAVA-EFDGRTFFPQQSVSKFWVALAALDAAD -RGRIKLDTPVVLTPSDLTLHQPIANEIRTAGTTLGALMSRALQQSDNTCNDFILRAIGGP -GSVRAFIDANNIAGVRFGPGERLMQSAYVADPVDGAQPVAVVNALARLQRGELISASSTA -RLLGTMSHTRTGPQRLKGGLAPGWSLAHKTGTGQQTGYNDIGILTSPGGRSYAVAVMIRR -TAAPIWSRMVVMQNVVRAVIA-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1P492_9ZZZZ ------------------------------------------------------------- ----------------------------------------------DNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A3S0MFW8_9BRAD --qDLKSEISRIESRIKGRLGVAVLDTGSDRRF-GYRKDERFPMCSTFKLMAAAAILKRVE -QGQETLEQRVHFSKSDLVTYSPATEKHLESGMTVAELCEAAITLSDNTAGNLMLGMLGGP -PGVTAFARALGDPLTRLDRTELALNEAVPGDP---------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=UPI000E1E7476 -----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFSAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIELATKMMTISDNTATNMLISKMGGK -ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] Serine hydrolase n=2 Tax=Cylindrospermopsis sp. CR12 TaxID=1747196 RepID=A0A0R0M7U3_9CYAN -----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFSAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIELATKMMTISDNTATNMLISKMGGK -ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 3335mG TaxID=2204170 RepID=A0A318ANW1_9NOSO ------NAVQALGGSFKGQVAIAVRDIDQGWSI-AWNGDKPHPQQSVSKLWVGIAVMAAVD -EGRLSLADPVVVKRSDLTLHQPIRAKVGPEGTTIGDLLQGAMTLSDNTCNDVLLWKVGGP -DAIRRMLAAKGIEGVGFGPGERELQARYLDDPYDGATANGITLGLSLLADNKLLSPASTR -HLLALMRASRTGPLRLKSGLKPGWTLAHKTGTGQSTGYNDIGLLVAPDGRRYAVAVMIAS -TREPIPVRMRLMGDVSRAIVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetia bacterium TaxID=2052181 RepID=A0A4P5WTD2_9BACT --qTLAERIQPLVQAHRGNAAVAIRHLETGEQF-LWRADLVQPTASLIKLPVMVTACRMAD -AGQLDLSKMLQLSDADKVPGSGILTGHFSAGLSVRDAMRLMIRYSDNTATNLVVREI-GL -PATAACMQELGYAETRLNSFVYRGDTTIAPERSGSTTALETIGLLEQIQRGTAAKPESCQ -AMLQHLESCDD-DTMLAAQLPKGTRIAHKSGAVA-ASRTDAGLIFGPGG-VFAICVLTTE -NEDDNNSAHELIAKVARAAWDHf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ATQ8_9BACT --qKLAATVNEMDGKLDGVLAVGILDLSTGQKY-LLHADEVMPTASSIKIAILAELYRQAQ -QSKLKLTDFYTLQQSDRVGGSGITSVFSPGMLTLRDVAGLMISVSDNSATNVIIDRV-GM -ENVNALLDSLGLTHTRLRRKMMDLKAA-SEGRENVANPREMMLLLENLYRGKVLNKQMTE -DFFNLLSVHKE--SYIPHNLPEDVKVANKPGELE-GVRNDSGIVFAGKR-PYVISVMTTY -LRRE-RDGGEAITKISDAAYQMf ->[subseq from] AMIN domain-containing protein n=1 Tax=cyanobacterium PCC 7702 TaxID=1173021 RepID=UPI00036F5DDE ---QLSSEVRKLMSRYNLDPGMFFLDLETGDYL-DINGEKVFPAASTIKFPILVALFEDID -SGRVKLNEILVMRRDLMTGGSGIMQKRPGTKFSLWETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALIVKNQLLSDASRS -RVLDLMSRVEN-KSLLPRGLGKGAIISHKTGTLGI-VLGDAGIIQMPTGRRYLAGIMVRR -PFGD-LAAKSFINQVSHLVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E4CUH7_9SPHN ----LDDQLFALGTNLDGKVGIAVHDPARGRMM-HFEGTALYPQQSVSKLWVALTALDQAD -RGELDLSEAGTVRREDLAVHSPIRKSVVANGTSYADFIARALTQSDNTANDMVLRRVGGP -EEVRRTLARKGFADIRFGPGERPMQSAYVADPVDGATPVAIAAALAQLHEGALLSDGSTA -QYLGWLSEVKSGPNRLKGGLPAGWSIAHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR -TQVPVPERMEMMHGVVRAIAG-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium TaxID=165695 RepID=T0HPJ5_9SPHN ------SVIRNLGQSFKGKVGIAVRRVGADWTV-AWNGNALFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTLTRNDLTLHQPSAALVAKQGTSYSDLMRRAMTQSDNTCNDALLRAGGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLSNPPDGAAPSSIVAALAKLKQGDMLSPASTR -LLLNIMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVPIPERWALMQAVSKAVAA-- ->[subseq from] Uncharacterized protein n=1 Tax=Phenylobacterium sp. RIFCSPHIGHO2_01_FULL_70_10 TaxID=1801945 RepID=A0A1G2WJW2_9CAUL ---ALAAYVDALGRNFQGRAGIAVRSLEGGWTA-AHDAEGLYPQQSVSKLWVALSVLDAVD -RQVIRLDDPVLVRRQDLSIHQPIRDFVGPRGTSVDELLESATTKSDNAANDVLMRLVGGP -EAVRAVIAEKELGAIGLADEERYFQTAYLAEPPDGATPVAVVEALERLHRGELLSPESTE -LLLTHLGASRTGPNRLGGGLAEGWTLAHKTGTGQATGYNDVGLLTAPDGATYAVAVMIAE -TTATIPERQALMQAVTRAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Anaeroarcus burkinensis TaxID=82376 RepID=UPI0003FE8F59 --kHLHTKLEQLAASCPCRWSVVVTDTDGREIY-SLRPDLIYPSASMIKVPILFEILRQAA -AGTLCLQEPLAPSASCRVGGAGILKELNPSLLNIRDLCVLMISLSDNTATNTLIERV-GM -AAVNQTMSDLGLSHTRLQRRMMDFAAA-EAGLQNETTAADMAKLYQLLLNAQGLPPAYAA -LALNILKTQQV-RDKIPFYLPESVSLAHKTGTLD-GVEHDGGVLYLPAG-PYIVCIFADG -LQ-SNAHGLQLIAQMGRAIYN-- ->[subseq from] serine hydrolase n=1 Tax=Novosphingobium sp. FGD1 TaxID=2692619 RepID=UPI001367BADD ---ALGQQITALGQGFDGDIGIAVEDVQTGAVA-EFDGRTFFPQQSVSKFWVALAALDAAD -RGRIKLDTPVVLTPSDLTLHQPIANEIRTAGTTLGALMSRALQQSDNTCNDFILRAIGGP -GSVRAFIDANNIAGVRFGPGERLMQSAYVADPVDGAQPVAVVNALARLQRGELISASSTA -RLLGTMSHTRTGPQRLKGGLAPGWSLAHKTGTGQQTGYNDIGILTSPGGRSYAVAVMIRR -TAAPIWSRMVVMQNVVRAVIA-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C8095E2 ---QLNTQVKALMARYSLQPGMFFLDIDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5318 TaxID=2019666 RepID=A0A2N6LAU6_9CYAN ---QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIQLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLAAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya frigida ULC18 TaxID=2107698 RepID=A0A2T1DYC0_9CYAN -----KADLQALALKMQLTPGIFLYELDSSAYL-DLNGGASFAAASTIKVPILIAFFQDVD -AGKIRLDELLTMRKELVAGGSGEMQGPVGTQFTALETVTKMITISDNTATNMVIARLGGM -SALDQRFRSWGLVSTAINSLLPDLSGT------NTTSPRDMALLMTRISQGELVSIRSRD -RVLDIMQRTVN-RSQLPQGLGKGATIAHKTGDIG-GMIGDVGLIDMPSGKRYALTVLVKR -SFND-DSAYDLVQKASRTVYQY- ->[subseq from] Beta-lactamase class A n=1 Tax=Hydrogenispora ethanolica TaxID=1082276 RepID=A0A4R1R8I5_9FIRM --------ILQAIDPTAMKCGFVIKNLRTDETA-LWNERQRVPSASLIKLPIMAEVLRQAQ -AGSYSLTRRIRVKQEDKVPFSILTLLETGNDYSLQDLITLMIVQSDNTAANLLIDLA-GM -EKVNRFLAGLGLSATLLQRKMMDGTAR-RAGRENFTCAADMARLLELLYREELVDAPSSA -RMLEIMKQQLD-TSMMMLQLPDETVVAHKTGELEQ-IDHEAGIVYLEGRD-YLFVMLVWD -APAN-RDARLAIGRASRAVYDYf ->[subseq from] serine hydrolase n=1 Tax=Prochlorothrix hollandica TaxID=1223 RepID=UPI00034D6A7F ----LKQKVQALVQEQDLTPGVMVVDLDTGDYY-SLNGDRLFATASMIKMPILLAFFEDVD -AGKIRLDEELVMREDLVATEAGEMQYPVGTKFTALETAEEMIRISDNTATNMLIDRLGGA -AALNQRFRDWGLTTMAINNLLPDLEGT------NVSTPQDFALLMELINEGNLLSMRSRD -RLLSILRTPVT-QTLLSPGLGEGATIAHKTGDIGS-LVGDVGLIDMPTGKRYLAVMMVER -PTND-NRAQELIRQMSRLTYG-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus sp. TaxID=1902408 RepID=A0A2D5DJP7_9SPHN -----VAEIDELWRNXPGTTGXAVRRXXGDWSF-GKRQDEXXPQXSVSXTWVSLTILXEVD -KGRIKLSDPVTIGVNDLAVHQPIRDRVIANGETVYSLIQQAITRSDNTANDALLWKAGGP -DAVNAFIRXKGLGAIRFGPGERLLQSDYLRDPMDGASPQAIVDALGKLARGELLSPESTR -LMLETMERTHSGPNRLKAGVPDGWDFLHKTGTGQATGYNDIGIMTAPDGTRYAVAVMLGD -TTASIPARMRLMQSVTRAVARY- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An269 TaxID=1965613 RepID=A0A1Y4FJB9_9BACE ----LQEQIQQITANTDAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD -KHHLPLSTSVFIRKEDLRPYSPLRDRYPEGNLPISELLTYTLQLSDNNACDILFDYIGGT -EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH -FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH -SKLSFEATERVIADISAVVFR-- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodopirellula sp. SM50 TaxID=595453 RepID=A0A2A2WH76_9BACT --dDLDRRITPLIGPYQGDVAVGIKNLSGEGEF-WYRHEQPMATASLIKLPLLVTTYQQID -SATVDPAQLIELTREDKVPGSGILTRHFSPGLPLIDAIRLMIRYSDNTATNLVIDQV-GL -PTTTETMKSLGLLHTQLHAKVYRRDTRSQRYGLGSTSAADMITLLEGIHTHQVASKSSCE -AMIAHLLSCDD-QVKLPAGLPSGTKIAHKTGGVSS-VRTDAGIIYGPGKQAFAICVLTEN -NKSAESAPHRLIADIGRAAFDVf ->[subseq from] Class A beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A1Y4E643_9BACE ----LQEQIQQITANTDAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD -KHHLPLSTSVFIRKEDLRPYSPLRDRYPEGNLPISELLTYTLQLSDNNACDILFDYIGGT -EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH -FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH -SKLSFEATERVIADISAVVFR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An19 TaxID=1965580 RepID=A0A1Y4JEQ3_9BACE ----LQEQIQQITANTGAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD -KHHLPLSTSVFIRKEDLRPYSPLRDRYPKGNLPISELLTYTLQLSDNNACDILFDYIGGT -EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH -FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH -SKLSFEATERVIADISAVVFR-- ->[subseq from] Serine hydrolase n=1 Tax=Virgibacillus necropolis TaxID=163877 RepID=A0A221MAB5_9BACI --kQLINSIESITKQAGGTWGISLDDLDKKETW-TSNEDELFYAASVIKVPILLAAFTAFD -QRKFSLSDTVKLRKEDLVGGSGVLQHMTPGTLTIYDLVTLMIIQSDNTATNMVIDLV-GT -KKIQQTMEDLGLENSRFYNKLMVVPANLEG--RNLVTAADMTSMLKQMVMGEVVSMHACE -QMIDMLKKQQL-QNCLPARLPEQWELAHKTGSISR-VCHDIGILYVGNRT-MVVSILSKG -VE--DRTSPKVIADIGWEIYHY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium cloacae TaxID=120107 RepID=A0A1E1F2Y7_9SPHN ------SVIRNLGQSFNGHVGIAVRRIGADWTV-AHNGNQLFPQQSVSKLWVSMAFLDAVD -RGKIRLSDTTTITRKDLTLHQPSAALVGNNGTTYSNLMNRAMTQSDNTCNDALLRAVGGP -DAVRGFLARRFIGNIRFGPGERLLQSNYLANPPDGAAPASIVQALAKLKEGDMLSPTSTR -MLLSVMGEARTGPQRVKGGVPPGWHYLHKTGTGQSTGYNDIGIMTAPDGTSYAVAVMIGS -TTEPIPVRWQLMQAVAKAVAA-- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4IKD0_9CYAN ---QLNSQLKTLIARYSLSPGIFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLDTITKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLSDRSRS -QALGIMRRVEN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-TRARVFISQVSKLVYG-- ->[subseq from] Beta-lactamase n=2 Tax=Thermoanaerobacterium TaxID=28895 RepID=W9EEV2_9FIRM ---SLHDDIMNFISNADGDIGVSVKNLKTGEII-SVNEDMMFPSASTIKILIMAQIYKMAK -EGYIRLTDNIVLSDFMKTDGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGLVNTKIQRKMMDFEAA-KSGKDNYTCPKDMTRLLEQMYSGKVVDEEYSI -KMIEVLKKQQD-LGRLDMYLPDDIVIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN -MTT-NLDGKIAIGKISKMVYDEy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf38 TaxID=1736217 RepID=UPI0009E74562 ------NAVQALGARFDGQVGISVRDIDENWGV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -RERLSLGDPVTVTRADLTVHQPIRTLVGKTGTTVGDLLRGAMTRSDNTANDVLLWRIGGP -AAVNRMLRDKSVTGVRFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -PLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPVPVRMRLMGDVTRAVIA-- ->[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium RIFCSPLOWO2_02_FULL_45_28 TaxID=1801864 RepID=A0A1G1PQ67_9BACT --qALQQSIKSEIGQFKGEAGIVIKDLGTGWEF-SYEKAKLFPSASLAKIPLMAACFLAVD -QGRIKLDRNIALKSADKLTGSGVLKDMPAGTFSVERLIGLMIYDSDNTATNIVTNLV-GI -DYLNNTFKSFGLKNTDLSRKIADYHSR-DKGIENYTTAEDMALLLDKIYRRSLGNKNVSD -QCISMLKLTRM-NDRIPKYLPVDITIAHKTGLEN-GVCHDAGIVFTNKGD-IIIVVLTKH -ANSNSAPSKGFIAKVSLHAYRYf ->[subseq from] serine hydrolase n=1 Tax=[Scytonema hofmanni] UTEX B 1581 TaxID=379535 RepID=UPI0004953D09 ---ALNSQIKALMNRYRLNPGMFFLDLQTGNYV-DINGEKIFSAASTIKFPVLVALFEEID -AGRIKLNEKLVMRRGLIANEAGTMQKPVGTKFSVLQTVTNMMVTSDNTATNMIIDRLGGE -TKLNQRFRNWGLQNTVIRNNLPDIGGT------NTTSPKDLVRLSALLTNNRLLSPQSRN -QVLAIMRRNHN-RSLLPAGIDKKAVIAHKTGTLRF-ILGDAGIIQMPNGKSYLAGILVRR -PNHD-DRAMYFIRQVSRAVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A550H166_9ARCH -----IDAIKKPAEGFKGKLGVSVKHLGTGESA-DLNGDMLFPTASVFKVPVIVEFYRQVE -DCMIGLDDQVLLRDSDKVPGSGILKELTEGLVSYRDLLSLMMIVSDNTATDLIVKTV-GF -DNINDAMKDLGLKDTKVTKYCRQILFSLGTEDNDITTPNEMLKLVEYIVEGKAAEPESCQ -AILDIMAKCQTGGYRIPKYLPNKLLLQRKTGSLP-GVRNDVGVITVKTGEKYILACFTMD -AE-DNYEAEEVIAKVSQAVYQYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Mn802worker TaxID=629773 RepID=UPI0012EAE697 ---DLVNAVQALGSGLKGDVGISVRDIDDGWVV-AWQGDRARPQQSVSKLWVAVAVMDAVD -RGTMSLSDRVTVRRSDLTLHQPIRALVGKEGTTVGALLRGAMTRSDNTCNDVLLWRIGGP -AAINRMLAGKGIVGVRFGPGERKLQARYLAAPMDGASANGITLGLTLLAQGKLLTPRSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -THQPIPARMRLMGNVTRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella muscicola CCMEE 5323 TaxID=2019572 RepID=A0A2N6K958_FISMU ---QLNTQVKALMARYSLQPGMFFLDIDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLTNNQLLSDTSRS -KALDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sp. SYSU K30005 TaxID=2666135 RepID=UPI0012D8875B ----LQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -IGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFQESHANNVTTAADMALLLEQIANKQLISEKACD -DMFEILAKQQF-RNRIPYLLPQNTVVAHKTGTLAS-VVNDAGIVQLPDNGNFIITVFSIG -NK-TEAEGASIITKLSRVTYNHf ->[subseq from] Beta-lactamase n=1 Tax=Aphanizomenon flos-aquae 2012/KM1/D3 TaxID=1532906 RepID=A0A0B0QIH7_APHFL ---ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD -AGKIQLDETLVMGKKHIVGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLQNTVMRNRLGDFQGT------NKTSAKDLVKLSALMENNQLLSNTSQL -QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR -PNND-PRGTDFIRQVSQVVYGYf ->[subseq from] Uncharacterized protein n=2 Tax=filamentous cyanobacterium CCP2 TaxID=2107700 RepID=A0A2T1CV85_9CYAN ----LLQKVTPIAQGTDLTPGVFVLDLDNGDYL-SLNGETTFSAASMIKVPLLLAFFQDVD -SGKIRLDEMLTMLEGDIVGEAGEMQFDGAGTYTALETAANMIITSDNTATNMIIRRLGGV -EVVNQRFREWGLQQTVLRNPLPDLEGT------NETSPRELSYLLARVSEGELMSMKSRD -RFLDIMERTVA-NGLLPASIGQGATIAHKTGDIGS-LLGDSGIVDMPNGKRYAITVMVKR -PHND-DRAFELIRQISGVTYDH- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. MK52 TaxID=2711156 RepID=UPI0013EA8A6D ----LDRTIARLGRSFDGDVGIAVRDVQTGWTS-DHRGLDLFPQQSVSKLWVALAAFDQVD -RGTLSLDRELSLTKADLTLHQPVRALALRPGTDARDLVIRALTQSDNSANDRMLREVGGT -GSIRATLAAKAIAGVRFGPGERSLQAAYTSDPMDGASPLGIVDALARLKQGRLLSQRSTE -EMLGIMSNTRTGANRLKGGLEPGWTLAHKTGTGQQAGYNDVGILTSPEGRSYAIAVMIGR -TDRPLGQRMALMQKVVGATID-- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012460585 ---ETLVKVKDAEAQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Olivibacter sitiensis TaxID=376470 RepID=UPI000405A205 ---ALRKKIEGLMEKHKGRFAVAFKDLTTGETF-LHDAHKNFHAASTMKTPVMVEVFRQAS -LGKFSVDDSILVYNRSIVDGSYYSYKKVGTKLPISDLLYRMITKSSNLATNIVIDLV-GA -KNVNKTMRAMGAKDIQVLRGVEDSK-AYEKGLNNTTTAYDLMLLFEQLAEENIIDKASCD -RMIEILMDQHF-RSKIPALLPEGVRTATKTGSLAT-VSHDSGVVFLPDGRKYVVVLLSDG -ID--KEEADKTLAQISRALYDY- ->[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. TaxID=1153 RepID=A0A2W6YT59_9CYAN ---SLTAKIKELAAQKDLVMQMMAIDLDSGTYV-QVGATQKIAAASTIKTPLLVAFFQDVD -AGKIKLDELLEISEDVMVGEAGDFQGPLGTKKTALETATQMIVISDNTATNMIIKRLGGL -AAVNQRFQSWGLNNIVANNKLPDLEGT------NTISTQDMVTILAMVSQGKLMTPRSRD -RFMDIMSRPIT-RTLLPQGIGADARIFHKTGDIGS-AVGDAGIIDMPNGKRYAIAVMVTR -PNND-QRANELIRQISRASYDYf ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. PCC 7507 TaxID=99598 RepID=K9PN19_9CYAN ---ELQTPIKALMARYRLTPGIFFMDLQTGDYL-NINGGKAFPAASTIKYPILIALFQEVD -AGKIKLSETLVMQRKHVAGGSGNMQQRVGTKISLLETVTKMMTISDNTATNMIIDRLGGK -ANLNQRFRSWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALMANNQLISDTSSS -QVLGIMIRCHN-RSLLPSGLGSGASIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-DRAKAFIRQVSQVVYGYf ->[subseq from] class A beta-lactamase n=1 Tax=Parabacteroides merdae TaxID=46503 RepID=UPI000EE076FD ----IENTLQEYIAGKDARIGVAVI-INSKDTV-SINGNRDFPMMSVVKFPLALTVAHWID -NNDMSLNDSIAFGENDLNEYSPMLKMYGKSRMTVRELFEWSLVESDNNAADILLKRIGGT -SGATSLMRQLNISEILIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYIEMRNTSRSYS -EISSMLEQCSTGRDRLAALLPINATIGHKTGTGFISAVNDCGYVKLPDGTRYSIAVFVAD -SSYDMAATSAIIAEISNIVWK-- ->[subseq from] Beta-lactamase n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A0B1Y3E8_9BACI ----LQENLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKERIRLEEEDLVNGSGILKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ESVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGASIISKLSRVAYNHf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SM23_52 TaxID=1703359 RepID=A0A0S8H5A1_9BACT ---ELRSRLQSRISESGAEVGVYFRNLASGDSL-LLDVESRVHAASMMKVPVMIQLYRDAE -AGRLSLDDSLTISKTSIVDGTPYEYARVGEKETVRQLTELMITVSSNLATNMLIELV-GA -ERVQATMRQLGADSIAVLRGVEDIK-AYRAGLNNTTTARDMGLIFSAIAEHRAASPESCR -EMIAILSRQQF-NEGIPAGLPPGTQVAHKTGSIM-GIRHDGGIVYPENGSPYVLVVLTRG -IT-DSASADRLITDVSRMVYA-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. PA-18-2419 TaxID=2575443 RepID=UPI0011084EB2 ------SQIRTLLASYSLNPGIFFLDLDTGNYI-DINGEKRFAAASTIKFPLLVALFQEID -AGRIKLTDKLVMRRDLRVGEAGTMQKPIGTKFSVLETATLMMTISDNTATNMVLDRLGGA -AKVSQRFRSWGLQNTAIRNLLPDIPGT------NTTSSKDLVRLAALVSNNRLLSPNSRN -QVLGIMRHVKT-NSLLPAGIGQGATIAHKTGTLRF-IIGDAGIIKMPNGKSYLAGVLVQR -PNYD-PKAGDFVREVSRRVYNY- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012476115 ---ETLVKVKDAEAQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=candidate division TM6 bacterium GW2011_GWF2_28_16 TaxID=1619077 RepID=A0A0F9YC03_9BACT --kQLQKNISEKCNSLTGLIGVSAYHIESKKWV-NCNADEFYPMASTYKLQIAAYCLSLVD -KKQINLQEKYKIKTLDLQRGSTIKK---GQQMSIAELIKLMIEKSKNDASDIILRMVGGP -DHVNNWLKTNGFNNMSVDRSVLEMLDKFYVDKKDTTTPKEMVNFLTQLFEKKLLSEDSTN -FLLQSMLKCHWGKEKIPGLLPQGTKIWHKTGRMDK-ITSDVGIVELPNKGHLVIALYTNK -SKSSIDIQERKMAQISKLLFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10 TaxID=1797944 RepID=A0A1F9XDK2_9BACT ---RMSQDMRRAVRTFQGGVSIYVKNLETGKEW-AYNADEKMPSASLIKLPIMIGVVEKIG -KGELSLDHPMVLTREARRSGSGHIKWRPNGEFTIGQLLEEMMAYSDNIAQELLIRAV-GM -KYLRERFAAFGLTATNITREGLSLA--PRTRIENYTTAREMGMLLEQIYRGQKFGGDSSA -RMIELMKHAKY-NDRLPRQLPAGWTIAHKTGLLRR-ACHDCGIVYSPAGD-YIICVLTRS -GR-SYRDAKRFISKVAAISYRYf ->[subseq from] HGF-1 beta-lactamase n=1 Tax=Alistipes sp. CAG:831 TaxID=1262698 RepID=R5ID00_9BACT --kDLRGDIEKVIAGRQATIGVAVMC---GDTViTVNNSRKYPLMSVFKLHVAVTALRKMD -AEGIPLDSTVLIRSEQLHEYSPLRDRYPGQDISYRNIVGYTVSHSDNNTCDLLIGFSGGI -DKVDSCIKSLGITDLNLTETEADMHGDIRNGYLNWSTPMSVVRLFEKIYSGEILSTEHSA -FLERILLECSSGQDKLKAGLPGDVPVAHKTGHSDRLGDADAGAIYMPDGRKCYVSVLIMD -SKETDEVNAGVMAEIAGIVYRYf ->[subseq from] serine hydrolase n=1 Tax=Acaryochloris sp. CCMEE 5410 TaxID=310037 RepID=UPI00058532A0 ----IKRQIQAWAAQSELKPAMFFLNPSTGEYL-DINGAKSISAASTIKIPVLLAFFEDVD -AGIIDLDEPLVMRPDLVASEAGSMQEPVGTTFSALDTAEYMIAISDNTATNMLIDRLGGA -KKLNQRFKSWGLKHTTIRNPLPDLEGT------NTISPQDMAALMLKLKDEDLLSSISRE -QALDILRQTVT-NTLLPQGIDKDADIAHKTGDIGS-VVGDIGLIDMPNGQHYVAAILVQR -PHND-PRAQELIRKISKLTYKTf ->[subseq from] Uncharacterized protein n=2 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A350CFW2_9PLAN --qTLAERIQPLVQAHRGNAAVAIRHLETGEQF-LWRADLVQPTASLIKLPVMVTACRMAD -AGQLDLSKMLQLTDADKVPGSGILTGHFSAGLSVRDAMRLMIRYSDNTATNLVVREI-GL -PATAACMQELGYAETRLNSFVYRGDTTIAPERSGSTTALETIGLLEQIQRGTAAKPESCQ -AMLQHLESCDD-DTMLAAQLPKGTRIAHKSGAVA-ASRTDAGLIFGPGG-VFAICVLTAE -NEDDNNSAHELIAKVARAAWDHf ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=1 Tax=Alistipes dispar TaxID=2585119 RepID=A0A4Y1WYF7_9BACT --dDLEHRLDEALEGRRARIGVAVR-TPDGRTI--RRGDVPLPLLSVFKVPVALAALDRAA -RERMPLSAPFDVGPERLDGYSPMRDSLPPEGVTLAGLIRYSISLSDNIACDRLLDFAGGP -AAVEEYLRGAGIGGFRIAASERTMHRATENQRLNTAPPSAVCELFARLLRGGLLPAEYDA -LLRSALEEAPTGANKLRAGLPGNVRLGHKTGSSDRTADNDAGYVLLPDGRSYCVAVFVTD -SRETDGTNAAIAAEISRAAYECf ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EB640E ---DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -QGRLSLADPVTVTRADLTLHQPIRTLVGKTGTTVGDLLRGAMSRSDNTANDVLLWRIGGP -AAVNRMLKDKGVASVCFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPARMRLMGDVTRAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. HI0020 TaxID=1822223 RepID=UPI0012E778F1 --rELDQAVSRIGGTFDGHVGIAVRDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRNADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHELASIRFGTDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKPGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium UBA11371 TaxID=2055770 RepID=A0A351LFT6_9CYAN -----KAEITAALAQYQLTPGIFILDPDTDAFL-DLNGSSAKSSASTIKIPILVAFFQDVD -AGKIRPDELLTMKAKFIAAGSGNMQKFPGSKYTALETATKMIAISDNTATNMLIERLGGA -EALNQRFVSWGLTATAIRNQLPDIEGT------NTTSAKDLASLIAFVNQGELLSLQSRD -RLLSILRRTER-NHLLPRGLGAGATIAHKTGYIG-AMLADAGLIELPNGKRYIAAVMVKR -PRND-PQAEKLIRQISRIAYQHf ->[subseq from] Class A beta-lactamase, subclass A2 n=1 Tax=Apibacter muscae TaxID=2509004 RepID=A0A563DFA6_9FLAO ------DSIQNVIKDKQATVGVGVIY-HNNDTL-SINNQYLYPTMSVYKFHQALAILNYLE -KNKLSLNTTYFIKKEDLDPYSPLFKERPEGNISIKDLLYYSICLSDNNVSNYLFRYLVNP -AQTEDYIKSLGTDEISIKRTEKEMSQNHDNQYLNWTRPLATAILFNKILNEKIFKEEYQD -FLIETLIKTNTGENKIKGLLPKDLIVGHKTGNSYRDADNDAGFVLLPNGKKYTLAIFIMN -SKETDEVNASIIAKISQLIYNYy ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. OV641 TaxID=1881068 RepID=A0A1H6X2Z6_9SPHN ---ALLNAVQALGRGFSGDVGISVRDIDEGWTV-DWAGDKPRPQQSVSKLWVGITVMDAVD -RGRMSLSDPVTVRKSDLTVHQPIRPLVDSDGTTVGALLQGAMTRSDNTANDVLLWRVGGP -EAVRRMLDDKDVAGVTFGPGERLLQARYLADPEDGASANGVTLGIALLAQGKLLSPASTD -KLLSLMRASRTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS -TRQSIPSRMRLMGDVSRAIVA-- ->[subseq from] serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium MTP1 TaxID=1751289 RepID=UPI0009EB7316 ---ALTNSIQNLIAQNGLTAGVYLVDQDNGNYI-DIGGAAALQAASTIKVPVLVAFLQDVD -AGKIRLDEELPMLESDVAEGSGEFQQAVGTKWTALETARQMIVISDNSATNMLIRRMGGA -QALNQRFRSWGLTATVINNPLADLAGT------NTTSAKDLTTLLTAVTQGKLLSLRSRD -RLMEIMQSTVT-NTLIPAGIGEDVLVAHKTGNIDT-MVGDTGIVDMASGKRYVLTVLVQR -PV-DDSRAQELIRQISNAVYQYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A166NHK6_PSEAI -------KLAELERQSGGRLGVALIYTADYSQI-LYRADERFAMCSTSRVMAAAAVLKKSE -SEPNLLHQRVEIKKSDLVHYIPIAEKHVNGTMSLAELSAAALQYSDHVAMNTLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLR-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9VUU2_9BACT --eKLTASIRQVDVELDGVLGVAIEDLTTGQKF-SLREDEVFAQASSIKIAVLAELYRQDQ -SGKAKLSDLYTVQASDLVPDSDIMGGLTPSVITNRDLATMMVAVSDNSATNVLIDRV-GM -ENVNRMLDSLNLPHTRLRRKMMDIKAA-AEGRENISTPREMLSLLEQIYRGKVLNQETTQ -EFLKMLSTHK--DSWLPRDLPDSVRVADKPGSLE-GVRNDSGIVFAQNR-PYAICVMTSY -LNK-ERDGENAISRISAAAYAVf ->[subseq from] serine hydrolase n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI00036E13CD ---ELRQQIEQELARHPGVFAVAFKDLTTGQEL-LIREKERFHAASTMKTPVMIEVYRQQA -QHKLALTDSILVKNESIVDGSPFSYKQLGTKRTLASLVYDMITVSSNLATNLIIEKV-DA -RKVTQTMRELGAKDIEVWRGVEDAKA-FAKGLNNTTTAYDLMVIYEKLAQGKVVSPEASQ -AMIGILLEQKF-NESIPAKLPKDVKVAHKTGSIT-GVRHDSGIVYLPDGRTYVLVILSKQ -IKEDLE-TQNAMATVSEW----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A7U968_ECOLX ----------------------------------------------------------ESE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVG--------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK235 TaxID=2512131 RepID=A0A4R2PJX4_9SPHN ----LLNAVEALGQRFPGAVGISVRDVERGWTV-SWQSGTRRPQQSVSKLWVALATFDAID -RGTLSLRKTVTVRRADLTLHQPIRARVGAGGITIAGLLDCALTRSDNTCNDVLLRQVGGP -AAVRRTLTRKGISGVTFGPGERLLQARYVASPPDGASADGVTLGLARLAQGRLLSKASTA -RMLALMRASRTGPLRLRSGLGRGWTLAHKTGTGQATGTNDVGLLTAPDGHRYAVAVLIAR -TRAPLRVRLRLMGDVTRAVVR-- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001444F1FD ---ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD -AGKIQLDETLVMGKKHIVGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLQNTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSNTSQL -QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR -PNND-PRGTDFIRQVSQVVYGYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Lindowbacteria bacterium RIFCSPLOWO2_12_FULL_62_27 TaxID=1817870 RepID=A0A1F6LAM5_9BACT ---RMSQDMRRAVRTFQGGVSIYVKNLETGKEW-AYNADEKMPSASLIKLPIMIGVVEKIG -KGELSLDHPMVLTREARRSGSGHIKWRPNGEFTIGQLLEEMMAYSDNIAQELLIRAV-GM -KYLRERFAAFGLTATNITREGLSLA--PRTRIENYTTAREMGMLLEQIYRGQKFGGDSSA -RMIELMKHAKY-NDRLPRQLPAGWTIAHKTGLLRR-ACHDCGIVYSPAGD-YIICVLTRS -GR-SYRDAKRFISKVAAISYRYf ->[subseq from] Serine hydrolase n=1 Tax=Larkinella rosea TaxID=2025312 RepID=A0A3P1BNF5_9BACT ---------------AQARVNVAFESLTDHTTF-VHLPDELVPSASVIKIPILIETMERVK -AGKFDLDQIHVLQASEKTGGSGVLQTYPDQSITNREVLTLMMTRSDNSATNILIREL-GM -ENINQRMRTLGLTQSRLNRMMMDTLAA-KQGRENRVTASEMNILLKKIYRNEVATPALCE -QMIDILKRNTD-QTTFRLFLPKSAVIAHKTGELSY-VRGDAGIFYVT--KPFLLTVFVQG -TT--TPEAEKIIGEIAEICYNQf ->[subseq from] serine hydrolase n=1 Tax=Fischerella muscicola TaxID=92938 RepID=UPI00036C4972 ---QLNTQVKALMARYKLQPGIFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLMTGGSGTLQKRPGAKLSVLETATKMITISDNTATNMIIDRLGGK -ARLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALLSNNQLLNDASRS -QALGIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V573_9BACT -------------------------------------------------VMAAAAVLKQSE -TQKGLLSQRVEIKPSDLINYNPIAEKHVNGTMTFGELSAAALQYSDNTAMNKLIAHLGGP -DKVTAFARTIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGGTQRA -QLVMWLKGNATGAASIQAGLPTSWVV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Nostoc sp. PCC 7107 TaxID=317936 RepID=K9QL89_9NOSO ---ELRSQVKALAARYSLDAGMFFLDLETGNYL-DLNGEKIFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLVTGGSGEFQKRAGTRFSLIETVTKMITISDNTATNMVIDRLGGK -AKLNQRFRGWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVAKNQLLTDSSRS -KVLDIMRRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR -PFNDL-KARDFISQVSRIVYG-- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter aquaemixtae TaxID=1958940 RepID=UPI00135F4352 ---ALDNALFAAANGFDGYLGVAIHDIARDRTV-HYNGERLFPQQSLSKLWVALAALQKVD -EGTLELAEPVSIRRSDLTLHQPVRKIVLARGTDYGDLLRRAITESDNTANDMLLKRVGGP -PGVRNAIAAAGLGAIKFGPGEREMQSAYVLDPVDGASPVAIADALGKLAKGELLEAPTTA -HFLDLLANVKSGPNRLKGGVPAGWLIGHKTGTGQQAGYNDVGILTAPDGSRYAVVVMIGR -TAVPVPQRMELMHAIVAATVHY- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI00068B092B ----LQENLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGASIISKLSRVAYNHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. (strain YBL2) TaxID=484429 RepID=A0A0C5XQP9_SPHYB ---DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-SFNAERMLPQQSVSKLWVAIAVMDAVD -RGTLSLSDPVMVKKSDLTVHQPIRSLVTKAGTTIGKLLELAMTRSANSCNDVLLWKVGGP -QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSGRSTR -HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGNRYAVAVMIAS -TRLPIPARMRLMGNVTRAIVR-- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0004A7EE3A ---ELQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RGRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGASIISKLSRVAYNHf ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00110702DD --kAIENTLQKYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWID -TNGMSLNDTVTFNEKAMKEYSPMLKKYGKSRMTVRELLEWSLAESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYRELGNASQSYS -EISVMLEDCRTGLDRLALLLPTNATIGHKTGTGFISAVNDCGYVKLLEGTKYSIAVFVAD -SGYDMAATSAIIAEISKIVWK-- ->[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E7UG09_9SPHN ----LDDRLFALGTGLEGKIGIAVYDPARSRMM-HYNGTQLFPQQSVSKLWVALTALDQAD -RGELDLSETGTVRVDDLAVHNPIRRSVVANGTTYRDFLERALTASDNTANDMVLRRVGGP -DEVRETLARKGFADIRFGPGERPMQSAYVADPVDGATPVAIASALARLHGGELLSQESTA -RYLAWLDDVKSGPNRLKGGLPEGWSIGHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR -TQVPVPARMEMMHGVVRAVAG-- ->[subseq from] Beta-lactamase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=G6FSV8_9CYAN ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C7FA3F8 ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000E0A69E7 ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001249161E ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012449D71 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00124942E2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001248DF18 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001247D821 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012453F42 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00124565A1 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. YH-07 TaxID=2182384 RepID=A0A345YAX9_9SPHN ----LAREIAMLADGSNGRIGVYAVDLATGHEV-GVLADQRFPMASTSKVAIAAAYLAGVD -EGRWSLTSEFRLPR-------------PGGALPAYKHLSLMISKSCNDCTDALLAAVGGP -RAVNKWMRNAGIEGFELSRDIRTLIRAWSVDAKDSATPRAMGQLLAGIYQGKWLSDHSRR -FLLDAMEETTTGKRRMRSALPVSANLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5201 TaxID=2019672 RepID=A0A2N6N4E0_9CYAN ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001243F231 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001247EF42 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001245CCCA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0012473325 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001245FBB3 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Saganbacteria TaxID=1703751 RepID=A0A1F4RBG8_9BACT --tKLRQKLDALVLPYGVKVGLCFIDLQNGKEL-QINGKNKFPAASVAKLPVMATGFHLAE -SGKLDLGQKVKFKEKDKLAGSGVLRWMKAGNYTIKNLIRLTIVLSDNTATRMAVRQI-GL -EEINNYLKKCGLNDTVIVDDTM-LNDPALTQNYNTTTPYDMARLVALIKNSAYFSAASKK -QMLAYMKFQRY-RWGLWKGVPKGIKIANKTGNLDR-VLNDVGIVYAPSGN-YALAIFTHG -FQKN-KTARKVINEISKVVYTVf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A5N8ACR8_9SPHN ---ELQRSIAALGQNFNGVAGISVRRVDADWEV-SYNGGRLMPQQSVSKLWVAMTMLDAID -RDRLTMSDPVTISGNDLTLHQPVAAMMKGGTTTLSDLYNRAMQQSDNTANDAILRKVGGP -EAVRGFLARRFIPDIRFGPGERLLQSDYLANPPDGAAASSITLALAKLKRGEMLSPSSTA -YLISTMEGAKTGPQRIKGGVPAGWRYGHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTAAIPERWQLMQGVSRAIAA-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A2W4IK62_9BACT ---SLEDELEKLSDKKKLRTGLFVVEPATGRYA-EMNGRQPFMAASMIKVPVLVSLLAALD -RKSVSLTEKLTIRKDLITGGSGYLQWRPVDSITVKEAAELMIIISDNTATNLLIDRLGGL -EKLNKQYSSWGLKNTKLNNLLADLDGT------NTTSPYDLCYMMGRIERGELISQSSRD -WMYSIMHRTRI-KTLLPQGLNPGDRIFHKTGDIGK-MVGDVGLVHTKDGKRYLVAVQVER -PHND-RRANELIRTLSRAIH--- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098FF2FE ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingomonas dokdonensis TaxID=344880 RepID=A0A245ZTW4_9SPHN ---ALLNAVQALGQSFDGDVGISVRDVDDGWVV-AWAGDKPRPQQSVSKLWVGITVMDAVE -KGRLTLDDPVTVRRSDLTVHQPIRPLVKGDGTTVGALLSGAMTRSDNTANDVLLWRVGGP -EAVRRMLADKGVRGVTFGPGERLLQARYLADPIDGASANGVTLGIALLAQGKLLKPASTD -KLLSLMRASKTGPLRLKSGLRPGWSLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPARMRLMGNVSRAIVA-- ->[subseq from] Penicillin-binding protein, transpeptidase n=3 Tax=Cylindrospermopsis raciborskii TaxID=77022 RepID=D4TIF5_9CYAN -----KTTIENLSAANNLIPGVFIVDIDSGGYV-DVSGNKNFSAASTIKIPVLVAFLEDVD -RGKIRLDEILTMEQEMVAGGSGNLRTMPGTKLKSIEVATKMMTISDNTATNMLISKLGGK -ELLNARFRSWGLVNTAIQSPLPDLEGT------NTTSPKELASLIAKVNQGELISMRSRD -LMLDIMRRTQR-DDLLPAGLGEGATAYHKTGDIGT-MLADAGLIDVPTGKRYIASIMVKR -PH-NEPAAAKLINSISQATYSY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Anabaenopsis circularis NIES-21 TaxID=1085406 RepID=A0A1Z4GE45_9CYAN ---QLRSQVQALAARYSLDAGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLITGGSGEFQKRAGSRFSLIETVTKMITISDNTATNMVIDRLGGK -AKLNQRFRGWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVAKNQLLTDSSRS -KVLDIMQRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR -PFNDL-KARDFINQVSRIVYG-- ->[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Nostoc TaxID=1177 RepID=A0A2Z6CV00_9NOSO ---QLRSQVQALAARYSLDAGMFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLITGGSGEFQKRAGSRFSLIETVTKMITISDNTATNMVIDRLGGK -AKLNQRFRGWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVAKNQLLTDSSRS -KVLDIMQRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR -PFNDL-KARDFINQVSRIVYG-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2E6RUG5_9SPHN ----LAREIAMLADGSNGRIGVYAVDLATGHEV-GVLADQRFPMASTSKVAIAAAYLAGVD -EGRWSLTSEFRLPR-------------PGGALPAYKHLSLMISKSCNDCTDALLAAVGGP -RAVNKWMRNAGIEGFELSRDIRTLIRAWSVDAKDSATPRAMGQLLAGIYQGKWLSNHSRR -FLLDAMEETTTGKRRMRSALPVSANLAHKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] serine hydrolase n=1 Tax=Pleurocapsa sp. PCC 7319 TaxID=118161 RepID=UPI00034CE117 ----LKVELEKLAEQYQLEPEMFLVDLDTKGFV-SLQGNKAIASASTIKLPILVAFFQDLD -RGKIHLEEQLTLTEEIIGSGSGNMQQEPGTKFSALEVADKMITISDNTATNMLIQRLGGQ -EALNQRFMDMGLTATRLQNPLPDLEGT------NTTSPEDLGNLLVKIDSGELISLRSRD -RLLHIMNNVVR-DTLLPQGLESGAIIAHKTGDIKS-VLGDAGIIDMPNGKRYIASVLVKR -PDND-PQAKEFIQKASQTAYQYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00045207F3 ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTHPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Leptolyngbya sp. NIES-2104 TaxID=1552121 RepID=A0A0P4UG00_9CYAN ----------TIAPQTQLTPGFMVVDADTHTYV-DVNASNPIPAASTIKFPILVAFFQAVD -EGKIRLDEPLTMRKELVATESGDLQTLPGSQFPAIEVATKMIDISDNTATNMIIDRLGGK -DALNQRFQSWGLTNTAIQNLLPDLPGT------NISSPRDMVALLDAVNRGELVSMRSHD -RMLNIMRKVAN-NSLIPQGLGEGSAIAHKTGDIGI-MLGDVGIIDLPNGKRYLMAAMVKR -PHND-DRAGDLIRQVSKLTYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas gei TaxID=1395960 RepID=A0A4S1XH02_9SPHN ------ASIDTITRNFSGLAGIAVTSIDDGWMAsNVTARRPLPQQSVSKLWVTMTVLDAVD -RGTVRLDDPLTITRADFTLHQPIASLVKGDTTTVAEIMRRAMQMSDNTCNDKLLRLVGGP -QAVRDFIARKQLGTIRFGPGEKLLQASYVKDPPDGAAPASIAEALARLKRGELLSPSSTD -WLLATMGGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYALAVMIGD -TSRPIRERQLLMQAVARAVVAY- ->[subseq from] Cephalosporinase n=3 Tax=environmental samples TaxID=48479 RepID=X2KYL7_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVFKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas naasensis TaxID=1344951 RepID=A0A4S1WHD7_9SPHN ---DLVAAIDTITRNFNGLVGVAVTSIDDGWMAsNVTATRPLPQQSVSKLWVSMTVLDAVD -RGVVRLDDPLTITRADFTLHQPVAALVKGDVTTVAEIMRRAMQMSDNTCNDKLLRLVGGP -AAVRDFIARKQLGSIRFGPGERLLQAAYVKSPPDGAAPASIADALARLHRGELLSASSTD -WLIATMAGAKTGKARVRGAVPPGWSYGHKTGTGQTAGFNDVGVLTAPDGRRYAIAVMIGD -TVRPIRERQLLMQAVASAVVAH- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pattaloongensis TaxID=405436 RepID=A0A1H3G8C9_9ACTN ---ALTKRLREIVDAADNRAGVAVRDLSGRRDI-AVNGSFRPPAASVIKLWILAELLRQVD -CGRLSLEKKVLVERRDVVAGAGLRDEKLPQRVPVRRLAELMITVSDNTATNVLIDTLGGV -APVNALIRALGQQQTQLGSKLYDPS---PRARGNYTSAVDVVSLLAAVWEGRLLSPASRD -FMIDLMRGQTI-DTKIPAALPPDAPVAHKTGELED-AAHDVGYYLIPGS-EVAVAFLTAG -PE---APGTELVRELARAVYDH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SGE9_9BACT --kKLETRVEEIAARLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ -KGKAKLNELYTFDPKDLVEDSQIMAGLTAGMVTNRDLAQFVVAVSDNAATNVLIDRV-GM -QNVNATLRNLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNKELTD -QLIKQLKTLKK-DSYLSYELPTGVDIADKPGSLE-GVRNDSGIIFAQNR-PFAISVMTAY -DR-DEKAAERAISEVALEAYHYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas jaspsi TaxID=392409 RepID=UPI0004B917AD ----LEQRLFSIANANPGNIGVAALDLKTGQLV-SVYGDDAFPMASTVKVAIAANYMSQVE -AGRRSLDATI-------------------GGQPVRSLMARMLIHSDNVATDMILNNLGGP -APVQAWIDQHGITGLRIDRTIASLLAAKRKDVRDSATPKAMVTMLQKLDSGAMLRPSSRD -YILDLMAQCATGKNRIPGLLS-GVKVQHKTGTLT-GLTTDVGYLTLPDGRRVAIAVFARY -GA----NRPATIATAARAVYDGf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A2A4TZV8_9BACT ---KMGAELEKAAQAYPARVGIMVRDLGRGWTY-TYHADDLFPSASLIKVPIMVGVFDKIN -RGRLSLHSKLKLRRSTRMGGSGRIKWRRDGTFSVRQLLEMMMQRSDNTAMLLLIDEV-GM -GYLQNFFPTMGLVYTEIYPEGLRLTSG-RVRYENYTTPREMASIFEKGYHGELVNSFASE -LMMDIMKGKK-GKTRLAKKLPIGWEIAHKTGLLRR-SCHDVGVVYSPNGD-FVISVLTGR -NA-SYGQAKRFITKVGEITYRHy ->[subseq from] Putative beta-lactamase n=2 Tax=Erythrobacter litoralis TaxID=39960 RepID=Q2N9V7_ERYLH ---ALDQALFDIAAPFDGYLGIAVHDIARDRTV-HFNGNEHLPQQSLSKLWVTLAALRMVD -AGELDLSERVSIRRSDLTLHQPVRQIVLARGTTYGDLMRRAITESDNTANDMLLKRVGGP -AGVRNAIGEARLGAIRFGPGEVPMQSGYVLDPVDGATPRAIALALARLARGELLEPGTTA -LFLQLLKDVKSGPNRLKGGVPPGWSIGHKTGTGQQAGYNDVGILTAPDGARYSVVVMIGR -TAVPLPVRMELMHKVVEAIVRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured soil bacterium TaxID=164851 RepID=M4QHL2_9BACT ---ETLVKVKDAEDQLGARVGYIELDLSSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009901C54 ------------------------------------------------------------- -----------HINKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Serratia fonticola TaxID=47917 RepID=U6A4F7_SERFO ---------------------------------------------------AVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYSDNTAMNKILEHLDGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVVGD-------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5330 TaxID=2019670 RepID=A0A2N6MGF5_9CYAN ---QLNTQVKALMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLRKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFQSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Uncharacterized protein n=1 Tax=Calothrix desertica PCC 7102 TaxID=232991 RepID=A0A433VGT7_9CYAN ----LETQIKTLMNRYSLTPGLFFLDLQTGDYL-NINGERIFPAASTIKYPVLIALFEEVD -AGRIRLDETMVMQRRHLAGGSGNMRFRSGTKFSLLETATRMMTISDNTATNMVIERLGGI -AKLNQRFRKWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRT -QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTPSGRKYLAGILVRR -PHHS-PQARDFIRQVSQLVYNY- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas endophytica TaxID=869719 RepID=A0A147I8C9_9SPHN ---ALQERVTQLIRSFPGKAGAAIQAVDEDWIV-SEGGALYLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVTRDDLTLHQPIASLVTAQGTTVGGLMTRALTQSDNTANDRLLTVVGGP -AAVRRFLAEKHISGIRFGPGERLLQSRYIDNPADGAQPAAIVEAMARLARGELLSETSTR -ILLDTMAASHTGRARLKAATPPGWKLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD -TTAPMRVRQVLIQQVAAAL---- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525JZD9_9CAUL ---ELQATLERIVQGYGEPVGIAVSDVTSGWTA-SVAGRETFPQQSVSKLWVALAVMQAVD -DHRLSLDQNVVMHAEDRSVYQPLASRIRGPNITLADLMRHALIESDNAANDMLIRQVGGA -GVVTQAIADKHLAGLAVGGTERDVQTNYLANPPDGATPDGITTALAALKRGELLSRASTD -FMLDLMGEARTGVMRLRAGVEPGWSLAHKTGTGPSVGINDVGLLTAPDGRTYAVAVMVRE -TKQPPSARHRLMIGVARAIEAYw ->[subseq from] Serine hydrolase n=1 Tax=Scytonema millei VB511283 TaxID=1245923 RepID=A0A1D2PFN1_9CYAN ---QLSSQLKTLIARYSLSPGMFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFEEVD -AGRIKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLDTATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLSDRSRS -QALGIMRRVEN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-TRARVFISQVSKLVYG-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Aeromonas sp. C_PIA_I1 TaxID=682902 RepID=D1LFF0_9GAMM ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWAVGD-------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=2 Tax=Alistipes sp. An54 TaxID=1965645 RepID=A0A1Y3WV54_9BACT ---TLEQDLEQLAASLEARIGIAIR-TPDGETI--SRQDVPLPLLSVFKFPVALAVLDKAD -AEGTPLTTPVEVGPEWLDPYSPLRDSLPATGVTLGELLRYSTSLSDNIACDRLLEYVGGP -NAVERYVEKAGIEGFRIAATERTMHLDPANQRINVARPSAVCALFARLLEGGLLTPEHET -LLQRLLEGAVTGTDKLRAGLPEGAVLGHKTGSSDRTADNDAGYVVLPDGRHYCVTVLVTD -SPADDAKNAAVIAAISKRIYEHf ->[subseq from] Beta-lactamase n=1 Tax=Cyanothece sp. (strain PCC 7425 / ATCC 29141) TaxID=395961 RepID=B8HM72_CYAP4 ----LQQRLAGYRKTYPAQSGMFFLDMDNGNYV-DLNGDKIFPAASIIKLPILVAFFQAVD -AGKVRLDEKLTLRPELFASGSGEMQQRPWTQFSAQYTAAQMIIISDNTATNLILKRLGGP -GVLNQQFRSWGLKQTVIRNWLPDLSGT------NTTTARELVNLLTLLDQGKLLTPSSRE -KALAILRQTKN-RKLLAAGLGPGAVFAHKTGDIGF-MLGDAGMIQMPTGKRYMAAVIAKT -PY-DDPAGWTFMREISKIAYTYf ->[subseq from] Serine hydrolase n=1 Tax=Natronospirillum operossus TaxID=2562806 RepID=A0A4Z0WE30_9BACT ---RLESRLEVVDTEFSGDLSVYVAHTGSGESV-SLRGHEHWYLASTIKVPVAIELLAQVD -AGERSLDDQVALEGRDYVDGAGQTNWHDGTEFTLEHLLQEMLVVSDNAASDMVIRTV-GI -DNVNTRMEALGLDFVGPITSLADVRRAYYQTPYNSGTLSAMGQMMARLVEGELLSADSTD -YLLDLLQTIETGDNRLRATLPDDARFAHKTGTQHR-RACDIGAVLAENDRSAVVVAVCTR -GPRSTAEAERAMRAVGEAVTE-- ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5268 TaxID=2019662 RepID=A0A2N6KCD7_9CYAN ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLRKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI000303AF4A ----LETQIKTLMNRYSLTPGLFFLDLETGDYL-NINGEKIFPAASTIKYPVLIALFEEVD -AGRIRLDETMVMQRRHLAGGSGNMRFRPSGTFSLLETATRMMTISDNTATNMVIERLGGI -AKLNQRFRKWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRT -QVLNIMYQCKN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTPSGRKYLAGILVRR -PHHS-PQARDFIRQVSQLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=UPI00119E2CC4 ------------------------------------------------------------- -------------------------------GASAHYLMDRMMVRSDNRATDELIATLGGP -RAIDRWLRGHGLTGIRVDRNIADLLAARRWDVRDSSTPLAMLELLRLVDGNLALSAQSRA -TLIDMMRRCATGSNRIRGMMPYGAVVENKTGTLNS-YTTDVGFLTLPDGRRLAVAFFARG -GE----NRPAVIATAARAIYDGf ->[subseq from] serine hydrolase n=1 Tax=Calothrix desertica TaxID=32056 RepID=UPI000F8C7BD9 ----LETQIKTLMNRYSLTPGLFFLDLQTGDYL-NINGERIFPAASTIKYPVLIALFEEVD -AGRIRLDETMVMQRRHLAGGSGNMRFRSGTKFSLLETATRMMTISDNTATNMVIERLGGI -AKLNQRFRKWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRT -QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTPSGRKYLAGILVRR -PHHS-PQARDFIRQVSQLVYNY- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=unclassified Acinetobacter TaxID=196816 RepID=D1LFE2_9GAMM ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Sphingomonas endophytica TaxID=869719 RepID=UPI000737052D ---ALQERVTQLIRSFPGKAGAAIQAVDEDWIV-SEGGALYLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVTRDDLTLHQPIASLVTAQGTTVGGLMTRALTQSDNTANDRLLTVVGGP -AAVRRFLAEKHISGIRFGPGERLLQSRYIDNPADGAQPAAIVEAMARLARGELLSETSTR -ILLDTMAASHTGRARLKAATPPGWKLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD -TTAPMRVRQVLIQQVAAAL---- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sinduriensis BLB-1 = JCM 15800 TaxID=1384057 RepID=A0A0A3HVR8_9BACI -----EKAILRLLEQAPFDIRLIIKDAGGSQFLlSKNPDDVFQSASLIKVPILLALLDSIE -NRNFTLHQTVQISKENRVEYSVLTEL-GTEECSLHDLLVWMIITSDNTATNVLIDLI-GL -ENINRYFKKVGLTQTKIQRKMMDFHQM-ARGFDNVTTAADMATLYTAIYRKSLLSKEHSE -LVIDILSRQRV-HESLRRYLVEDVKMAHKTGSLAT-VEHDVGIVFSSKRD-YIIGVFVTD -HTNS-EEAKRFIGQVSKIVYDH- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00068952B7 ----LQENLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ESVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGASIISKLSRVAYNHf ->[subseq from] Peptidase_S11 domain-containing protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A353ZAM2_9PLAN --qTLDRRLKGLIEDHDGEVAVAVEHLQTQERF-GFRSDEVMSAASLIKFPVMVEVYRQSE -QGQIELHQFLELTEQDKVPGSGILTPHFSPGLAIVDAVRLMIAFSDNTATNLLLDKI-GL -GATTETMRTLGFPNTRLNSKVYRRETRSREFGLASTTADEMVGLLRLLHERKLVSPKASD -AMHAHLLNCDD-HHKFPRFLPEGAKVAFKTGSTE-AIRSAAGILETPRG-PVAICVLTSE -NASEDNEGDVLCARIAREVWDYf ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A2N7Q988_9BACT -------NILKRISTFRGEAGITVKDLKTGWTF-LHNEDQPFPAASLVKIPVMVACFKAAQ -DGLIDLEAGYVLQRKDKTGGSGLLRRMRSGRFTFRELVDYMVTESDNTAANILIDKL-GF -DYINRVFREIGLKKTVLNRKMIDFNAR-DQGMENYTTAAEITSLLEKIYYGQCFNQEISQ -KCLEVLKRQKI-NDRLPRYLPKGVIVAHKTGLEKE-VCHDAGIVFTPYGD-YIITVLVHT -WGGP-TTAKNFIARLSSYFYQVf ->[subseq from] Serine hydrolase n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519J306_9CAUL -------ALVAHAAQADGVLGACIVD-RHGAAC--ANGDRPISMQSVMKLLVGMAVLDAVD -QGRLTLDDEVLLTRDDVSVFVQPLEKLIGPDTTVGELIRGAITESDSLATDWLIDRLGGT -AAVQAYLDRKGIVGVRLDRDERRLQTAYQNDVRDTATPRGLATLLYRLGDGQLLSAGSTR -WILDVMGETGTFPDRLRAGTPADWWIGHKTGSSSVGVTNDVGVMRAPDGAVIGVVALLAN -SSAPAPERAAAIAGVSRIAAET- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2D8TCP7_9SPHN ------SVIRNLGQSFRGKVGIAVRRVGADWTV-AWNGTALFPQQSVSKLWVSMTFLDAVD -RGKLRLTDTTTITRNDLTLHQPSAALGARDGTSYSDLMRRAMTQSDNTCNDALLRAAGGP -DAVRGFLARRMIKDIRFGPGERLLQSNYLANPPDGAAPSSIVAALAKLKQGDMLSPASTR -LLLNVMSEAKTGPQRVKGGVPAGWHYLHKTGTGQSTGYNDVGIMTAPDGTSYAVAVMIGS -TTVPIPERWALMQGVAKAVAA-- ->[subseq from] serine hydrolase n=1 Tax=Negadavirga sp. SW125 TaxID=2164132 RepID=UPI000E0A8D1D --eELKSKLEERVTQVDGTIAVALKVLEGGKETlFIHEREVFHAASTMKTPVMMEIYRQAE -QGKFSLSDSIPVVNESIVDGSPFSYHMIGQKETIYELMYQMIIKSSNLATNILIDLI-GA -SNVNEFMREIGANDIQVLRGVEDLKA-FEAGLNNTTTALDMMLIMEAIATGKAVNQEASL -QMMDILYDQYY-KDLIPKKLPEEVKVAHKTGSIT-GVQHDAAILELPDGKRYVLVILSKE -LK-DVEEGKEAIADISRQIYQY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A4U0_RAHAQ --------------------------------------------------MAASAILKESE -VKKNLLTQHVVLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QLY0_9SPHN ------------------------------------------------------------- -------------------------------GASAHYLMDRMMVRSDNRATDELIATLGGP -RAIDRWLRGHGLTGIRVDRNIADLLAARRWDVRDSSTPLAMLELLRLVDGNLALSAQSRA -TLIDMMRRCATGSNRIRGMMPYGAVVENKTGTLNS-YTTDVGFLTLPDGRRLAVAFFARG -GE----NRPAVIATAARAIYDGf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas ginsenosidivorax TaxID=862135 RepID=A0A5C6UJM8_9SPHN ---DLLNAVQALGARFQGAAGISVRDIDEGWVV-AWEGDTPRPQESVSKLWVAIAVMDAVD -RGRLSLADPVTVTRSDLTVHQPIRTLVGADGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLADKGIAGVTFGPGERQLQARYLADPIDGASANGVTLGLSLLAQGKLLGARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. ZYM-1 TaxID=1681184 RepID=A0A0N8IKA0_9BACI ----LQERLEEIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVE -VGRVELKERIRLKEEDFVNGSGIFKELIPGVVTIKNLATMMIIVSDNVGTDKLLNIL-GK -ENVNLFMKEIGLCNTYIHFSCWELLCFQESHENNVTTAADMAALLEKIANKQLISDKACE -DMFEILAKQQF-RHRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NK-TEAEGASIISKLSRVTYHHf ->[subseq from] Beta-lactamase class A n=1 Tax=Stakelama pacifica TaxID=517720 RepID=A0A4R6FWF8_9SPHN ---ALTAIIQSAVRNFDGKAGVAVESVDDGWIV-SANGETLMPQQSVSKTWVAMTVLAQRD -EGRLSLDDPLTITTADLTLHQPIAALVQKNGSTVGEIMKRALTMSDNTCNDKLLWLVGGP -PAVRAFIESRKLGAIRFGPGERLLQSAYIADPPDGAAPVAIADALARLKRGELLSAGSTS -WLITTMQSSHTGRNRLRGEVPGDWLFGHKTGTGQTAGYNDVGILTAPDGRSYTVAVMIGD -TARTIPQRWELMHTVVKAIVN-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter vulgaris TaxID=291985 RepID=UPI0005961D5D --sQLEKTVASLADGSRGRIGVYAIDLTTGQEI-GVLEDQRFPMASTSKVAVAAAYLAGVD -AGKWSLTSEWRLPR------------RGGAYLTGLEHLNLMISKSCNACTDALLEAVGGP -AAVNKWMRDAGIEDFQLTRDIATLVRASSVDLRDSASPRAMGQLLAGIYQGRWLSTSSRA -VLMDAMRATTTGKKRMRSALPTSAGLANKTGTLSR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. (strain YBL2) TaxID=484429 RepID=UPI000A059ED2 ---DLLNAVEGLGQSFKGEVGISVRDLDEGWTV-SFNAERMLPQQSVSKLWVAIAVMDAVD -RGTLSLSDPVMVKKSDLTVHQPIRSLVTKAGTTIGKLLELAMTRSANSCNDVLLWKVGGP -QAIRAMLKRKGLDDVGFGPGERKLQARYLADPYDGASANGVTFGLMRLKQGKLLSGRSTR -HLLGLMRASRTGPQRLRSGLRKGWTLAHKTGTGQATGYNDVGILVSPDGNRYAVAVMIAS -TRLPIPARMRLMGNVTRAIVR-- ->[subseq from] serine hydrolase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=UPI00140335D4 ---ELQARLTELAEDYREDVGIAVTDVTERWTA-SVDGGSLYPQQSVVKIWVALAMMEAID -QGRFRLDQPVLVRPEDRSVYEPLGRKIGRTGTTYYDLLSRSLTESDNTANDKIMSEVGGA -AIVTDVVARKGLTGIGIGGDEKMLQSAYLANPPDGATPIGLTHGLAALQRGELLSKPSTD -TLIGLMAEAKTGNLRLKAGLPPGWSIAHKTGTGPSVGINDVGLITAPDGRVYAVAVMLRE -TKRPFRDRQRLMQQVARAVADHw ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V577_9BACT -------------------------------------------------VMAAAAVLKQSE -TQKDLLSQRVEIKSSDSINYNPIAEKHVNGTMTLGELSAAALQYSDNTAMNKLIAHLGGP -GKVTAFARAIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQALRNLTLGNALGDTQRA -QLVMWLKGNTTGAASIQAGLPTSWVV---------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=UPI0009FE097F ---ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HQRLSLATPVTVTRADLTVHQPIRPLVGSSGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLLSHGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS -TRQSIPVRMRLMGDVTRAVIR-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645AR96_9ZZZZ ---ELKNNIENIISNSNGNIAVALRMMNDKSTI-MINENMIFPSASTIKLVIMSTLMREVK -EGRMSLNDRIKLLNCSKCGGDGILKELEEGHFTLKEIITLMIILSDNTATNILIDML-GM -KKVNEEAERLKLYNTQLRRKMMDSVAA-KMGRENVTTAKDLCSILESIYERKLVSEEYSE -IMLDILKRQQV-GGRLNLYLPEDLVIAHKTGDLDK-LEHDVGIVFHPKD-NYIICVLTKK -VD-TNKEGKEIIGKISHEVYK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W5PH40_9SPHN ---ALQERVSQLIRAFPGKAGAAIQAVDEDWIV-SQGGTLYLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVTRDDLTLHQPIAGLVTADGTTVGSLLTRALTQSDNTANDRLLTVVGGP -AAVRRFIADKRLGAIRFGPGERLLQSRYIDNPPDGAQPVAIVDALARLARGELLSETSTR -VLLDTMAASRTGHARLRAATPPGWKLSHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD -TTAPMRARQVLIQQVAAAL---- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium deserti TaxID=1914756 RepID=A0A328ATW1_9CAUL ---ELQARLTELAEDYREDVGIAVTDVTERWTA-SVDGGSLYPQQSVVKIWVALAMMEAID -QGRFRLDQPVLVRPEDRSVYEPLGRKIGRTGTTYYDLLSRSLTESDNTANDKIMSEVGGA -AIVTDVVARKGLTGIGIGGDEKMLQSAYLANPPDGATPIGLTHGLAALQRGELLSKPSTD -TLIGLMAEAKTGNLRLKAGLPPGWSIAHKTGTGPSVGINDVGLITAPDGRVYAVAVMLRE -TKRPFRDRQRLMQQVARAVADHw ->[subseq from] class A beta-lactamase n=2 Tax=Coxiella burnetii TaxID=777 RepID=UPI0000DAEA03 ------------------------------------------------------------- -------------KKNELVSYSPITKNHINGGITVSELCAAALTLSDNSAANLLIKKLGGL -TAINAFARSIGDKQFELDRLEPQLNSAIPGDIRDTTTPEAMANSLKRLTLGDILAFP--- -QLTTNMVKKIILQEMPKSELAFRKTVGDKTGSGGYGTTNDIGIIWPPKRAPIVVAIFFKK -NKKGAVSPDSIIERITRILM--- ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. TaxID=47254 RepID=A0A2W6ZXN8_9CYAN -------GLQSLIQQNKFKPGVFLVDLDSNDYL-DLSGAASFSAASMIKLPILIAFFQDLD -SGKIQLDEKLVMRQEVVADGSGDLQYLPGSQFTALDTVTRMITISDNTATNMLVARLGGM -SSLNQRFKSWGLSTTTLNKPLPDLQGT------NTSSPKELASLMVRVSQGDLVSLRSRD -RMLDIMRRTIN-NSQLPQGLGEGATIAHKTGDIGT-LVGDVGLIDMPNGKRYATAVFIKR -SFND-DAAYDLVQKISRLIYQH- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001249007B -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Sphaerobacter TaxID=2056 RepID=D1C1J1_SPHTD ----TIERIRALAEDFAGTIGVAARDLDTGTEV-MYNPDVVVPTASTMKTVLLYELYRQVD -AGQIDPAMRITLEERHRVPGSGVLQDLDAGVPTVKDVATLMITVSDNTATDMIYDLI-GR -EAVATTLERLGMTNTHLPLDTWEILALRETPDNDVSTPRDMLRLVEAIFRGEGLSPASRE -AVIDILKRQKY-TTIIPEQLPFGVKAAHKTGTLR-GVRNDVGLVFAGER-TYAVALMSKG -SP-NLVASQRLLSDISRLIYECf ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. An51A TaxID=1965640 RepID=A0A1Y3WYF1_9BACE ----LQEQIQQITANTDAHVGVALI-IDGKDTI-TINNDDRYPLMSVMKYHQALAVAHYLD -KHHLPLSTSVFIRKEDLRPYSPLRDRYPEGNLPISKLLTYTLQLSDNNACDILFDYIGGT -EETDKYLRTIGCDQFAVTATEDDMHKNLALCYNNWSTPLSTARLMDRLAAETLIDTSYTH -FIRETLLDCQTGKARLPFPLQTETRIGHKTGTSDQNGINDAGFILLPNGKRYTLVVFVKH -SKLSFEATERVIADISAVVFR-- ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=Rahnella TaxID=34037 RepID=U6A718_RAHAQ --------------------------------------------------MAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. HMP27 TaxID=1487921 RepID=A0A099SCY6_9CLOT ---ELKNNIENIISNSNGNIAVALRMMNDKSTI-MINENMIFPSASTIKLVIMSTLMREVK -EGRMSLNDRIKLLNCSKCGGDGILKELEEGHFTLKEIITLMIILSDNTATNILIDML-GM -KKVNEEAERLKLYNTQLRRKMMDSVAA-KMGRENVTTAKDLCSILESIYERKLVSEEYSE -IMLDILKRQQV-GGRLNLYLPEDLVIAHKTGDLDK-LEHDVGIVFHPKD-NYIICVLTKK -VD-TNKEGREIIGKISHEVYK-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium Pla123a TaxID=2528002 RepID=A0A5C5YTU3_9BACT ----FNSSLVDLLESHRGTVSAAAKHLPSGEEF-SFQADRPMPTASLIKLPILATAYHAAA -EGKVDLDAMVTLKEEDKVPGSGVLTANFSAGMPLHDAIRLMIAFSDNTATNLVIDQI-GL -PATNEYMDQLGLNNTRLHAKVFRRDTSIAPERSGSTSASEMLKLLEQIERGELISKQASK -SIYEHLLACES-RSKVPRYLPEETRVAHKTGSVS-AVRCDAGIIESPKG-PIAFCILTGD -NEGDENEAELLAAEFGKAIYAHw ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. CCP-7 TaxID=1979270 RepID=A0A437LYL1_9SPHN ---ALDRRIEALGAAFRGDVGLAVRDIQTGWTS-HYRGLDYFPQQSVSKLWVAISAFDMAD -RGKIDLHGKLSIRADDLTLHQPIKSLATRPGTDREDLLTRALTQSDNSANDKMLREVGGP -DAVRATLAAKSISGIRFGPGEKGLQSAYVADPIDGARPLAMVDALARLKNGQLLSDASTA -QMLDIMGQTRTGALRLKSGLRPGWTLSHKTGTGQQAGYNDVGILTSPEGRSYAIAVMIGR -TSRPLPERMDLMRKVVRTTIT-- ->[subseq from] serine hydrolase n=1 Tax=Aphanizomenon flos-aquae TaxID=1176 RepID=UPI000488404E ---ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD -AGKIQLDETLVMGKKHIVGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLQNTVMRNRLGDFQGT------NKTSAKDLVKLSALMENNQLLSNISQL -QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR -PNND-PRGTDFIRQVSQVVYGYf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GD88_9BACT --kKLETRVEEIAGRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ -KGKAKLNELYTFDPKDLVEDSQIMAGLTAGMVTNRDLAQFVVAVSDNAATNVLIDRV-GM -QNVNATLRNLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNKELTD -QLIKQLKTLKK-DSYLSYELPTGVDIADKPGSLE-GVRNDSGIIFAQNR-PFAISVMTAY -DR-DEKAAERAISEVALEAYHYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009907C70 ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase class A n=1 Tax=Parafilimonas terrae TaxID=1465490 RepID=A0A1I5WC18_9BACT ---QLKDKIAAQIEKHKGRYAVAFKNLSNGEEI-LINEHENFHAASTMKTPVMIEVFKQVQ -AGNFSMNDSITLKNESIVDESSFSYKHIGENRSVYQLMYNMIIMSSNFATNLIIDLV-GA -ENANETMREMGAKDIQVLRGVEDD-KAYEKGMNNTTTAYDLMLIFSKIANGEIVSKPACD -SMIDILSNQHF-NSVIPAKLPKDVKVAHKTGSIIS-VQHDSGIVFLPDGKKYVLVLLSKD -WT-DEKDAIGLMADISKTIYDH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudochrobactrum sp. C_SS_V3 TaxID=683080 RepID=D1LFE0_9RHIZ ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4REK9_9CYAN ---QLSSQVRSLMSRYSLDPGLFFIDLETGNYV-DYNGEKAFSAASTIKFPILIALFQEID -AGRVKLNETLTMRRDLVTGGSGTMQYRAPGTFSLLETATRMITISDNTATNMIIDRLGGK -NKLNPRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALVANNQLLSNSSRT -RALDIMRRVEN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR -PFGD-RRGTEFISQVSRTVYS-- ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes megaguti TaxID=2364787 RepID=UPI0013CF3A27 ---TLEQDLEQLAASLEARIGIAIR-TPDGETI--SRQDVPLPLLSVFKFPVALAVLDKAD -AEGTPLTTPVEVGPEWLDPYSPLRDSLPATGVTLGELLRYSTSLSDNIACDRLLEYVGGP -NAVERYVEKAGIEGFRIAATERTMHLDPANQRINVARPSAVCALFARLLEGGLLTPEHET -LLQRLLEGAITGTDKLRAGLPEGAVLGHKTGSSDRTADNDAGYVVLPDGRHYCVTVLVTD -SPADDAKNAAVIAAISKRIYEHf ->[subseq from] serine hydrolase n=1 Tax=Clostridiales bacterium mt7 TaxID=1631345 RepID=UPI000C75BB79 ---NLQESIERVVAQQQGTFGVYVKHLITMESA-SVNGDRLFQTASVFKVPILATLMRDVV -EGRSDLNQRVRLTSEDIVPGSGIFKELEPGVVTIKDLATMMIIVSDNLATDQVLSIV-GK -ERVQEYMSELGLSKTFIRFNCWELLSYQETSENNVSTPVEMGILLEHIVTKKVISEEASA -KIFDIMTKQQL-RNRIPRLLPKGTLVGCKSGTLGS-VVNDCGIVQLPDKKGLFVIAVFSK -DNPTIPQGEEVIAKLALTAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonas sp. RIT328 TaxID=1470591 RepID=A0A031HN48_9SPHN ------------------------------------------------------------- --------------------------------RSAAQLMELMIVRSDNHAADQLLAAVGGP -VAVQQWLATNGIAGIRVDRTIAQLLRE-PGDSKDVATPNAMVALLDKL-NGPLLSAESRG -LLFGLMSRCATGTRRIRALLPAGTRVEDKTGTLD-GVTNDVGFITMPDGRRLAVAVFARG -GR----DRQPGIAAVARAIYDRf ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-114 (HZI) TaxID=2486475 RepID=A0A3N2NHE2_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVIKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3S3R2_9CAUL --eTLQRRLNALALQFPGDVGIAVRRLGAGWTV-SVNGDRPMPQQSVSKLWVSMAILAAAD -RGELSLDETVLIRKQDLSIHQPIRRYVGEAGASLRSLMAGALQQSDNAANDALVRRLGGP -FAVQVAIVGRNLDGIRYGPGERAMQTAYLANPPDAATPLGLVEALSRLHGGELLSPGSTA -LMLQEMGGSLTGGGRLRAGLPTGWRLAHKTGTGQATGYNDIGLITAPDGRVYAVAAMIAA -TRRPLPERQRFMVGVARAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Trichodesmium erythraeum (strain IMS101) TaxID=203124 RepID=Q10XW0_TRIEI ---ALKTELDTIITKFSLTPGVFLIDTDTGAYV-DINGDATMAAASTIKLPILVAFFQAVD -QGRIKLNDLLTMKESHVAEGSGNMQRNPGSKYTALQTVRKMIIISDNTATNMLIEELGGA -EILNQSFQSWGLKNTVINNSLPDLSGT------NTTTSKDLINLISQINQGGLVSLKSRD -RLFRIMERTQN-NSLLPRGVGRGSVVAHKTGNLKS-MLADVGMIDLVNGRRYLLAVLVKR -PDED-QDAVDLIRRVSKETYKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Chamaesiphon minutus (strain ATCC 27169 / PCC 6605) TaxID=1173020 RepID=K9UAP8_CHAP6 ----LKSQIKALAAKYSISPGMFFMEVETGNYL-DINGEKSFPAASTIKLPILMALFQAVD -AGKIKLDEKLTVRRDLITGGSGRLQNSRGAKLSVLQTATKMIVISDNTATNMIIDRLGGR -KALNSKFKSWGLRKTVLNRMLGDFKGT------NTTSPADLVRLSALLAKRQLITETSRS -KVLDILNQTAN-RKLLPAGLGKGAAIAHKTGTLGR-LIGDAGIIEMPNGKLYLAGIFVKR -SFND-VRARDFVQAVSKLTYNY- ->[subseq from] Serine hydrolase n=2 Tax=Proteobacteria TaxID=1224 RepID=A0A520JET2_SPHSX ----LAANVTQLVRGFTGKVGVAVRSVDDGWLI-DAGGSQRLPQQSVSKLWVAMTVLSARD -AGKLRLDDPITLTRDDITLHQPIAGLIRGDTTTVGELLQRALTMSDNTANDRLMRLVGGP -NAVRGFIARKGLGAIGFGPGERMLQARYVANPPDGAAPTAITGALARLKRGDLLSAASTS -YLIGTMQSSHTGKMRLRGAVPAGWSFGHKTGTGQTAGYNDVGLLIAPDGRTYAIAVMIGD -TLRPIPARQQLMQAVVSSVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas taxi TaxID=1549858 RepID=A0A2W4YW50_9SPHN ---DLLNAVQALGAGFKGQVGISVRDIDEGWVV-AWDGDRPRPQQSVSKLWVAITVMDAVD -RGRLSLTDPVTVTRADLTLHQPIRALVGKDGATIGELLRGAMTRSDNTCNDVLLWRVGGP -VAVNRMLADKGVSGVKFGPGERQLQARYLAAPIDGASANGITLGLSLLSQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS -TRQAIPVRMRLMGDVTRAIVA-- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001243A1F1 -------KVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00115502D6 ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Scytonema sp. NIES-4073 TaxID=2005464 RepID=A0A1Z4PRX2_9CYAN ---QLNSQLKTLLARYSLSPGMFFLDLDTGNYL-DFNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLDTVTKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLSDRSRS -QALGIMRRVEN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-TRARVFISQVSKLVYG-- ->[subseq from] Uncharacterized protein n=1 Tax=Synechococcus lividus PCC 6715 TaxID=1917166 RepID=A0A2D2Q424_SYNLI ---------------------MYFFNLDSGAAL-NVGGDDVFPAASTIKIPILVAFFKAVD -ENRISLSERLTMRPDLIAPEAGTLQQKPNSQYPALEVADLMITISDNTATNMLIDRLGGA -AVLNQQFQEWGLKNTVINNLLPDMEGT------NTTSPRDLATLMLKIGQGELVSPRSRD -RLLDIMRRTVT-NTLLPAGIGPGATIAHKTGDIGT-VVGDAGMVDMPNGQRYVAAMMVKR -PYND------------------- ->[subseq from] serine hydrolase n=1 Tax=Anabaena sp. PCC 7108 TaxID=163908 RepID=UPI000364E537 ---ELQTPIKALMARYRLTPGIFFMDLQTGNYL-NINGDQPFSAASTIKYPILIALFQEVD -AGRINLNETLVMQRKHVTGGSGDMQRRVGTKLSLLETVNKMMTISDNTATNMMIDRLGGK -ANLNQRFRAWGLQSTVIKNMLGDFKGT------NKTSAKDLVRLSALITNNQLISDTSRS -QVLGIMIHCHN-RSLLPSGLGNGASIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-SRAIAFIRQVSQVVYGYf ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacterium sp. IPPAS B-1200 TaxID=1562720 RepID=A0A1E5QSN2_9CHRO ------------EKYANLQPSLFFVDLDNGAFV-NMNGMEAFPAASTIKTPILVAFFQDVD -EGKILLDEKLTMTEETKATEAGTMQYQPGTQYTALKVAEEMIIRSDNTATNMLIERLGGV -EALNQRFKEWGLESTVINNYLPDLEGT------NTISARDLAMTLVKVSNGNLVGTRSRD -RLLGIMQRTIT-RTLLPQGIEPDAMIYHKTGDIGK-VLGDGGIIDIPTGKRYVGAVLVQR -PHND-YTARTMIQEISREAYQHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus niameyensis TaxID=1522308 RepID=UPI000781F890 ---RLITNIQNAVEQVGGTWGIALKDLDTQETW-DLNGDELFYAASVIKVPIMAAVFNAFD -KGEFTLSDTIILKREDLVGGAGILQFMTPGAFTIHDIMTLMIIQSDNTATNMLIDLV-GI -ANIQKTMKDIGLKRSSFYNKLMTVPVH--IDGKNLITAGEMATLLEKIACGKVVSVYACE -QMIDIMKKQQI-RDCLPGKLPPEWELANKTGWVS-GCRHDIGIFYVGKRK-MICAVLSKD -VD--DGKSLQVLAEIGKLIYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. URHD0007 TaxID=1298856 RepID=A0A2U1G0L6_9SPHN ---DLHRQLIGLGRAFDGKAGIAVVSLRDGWEI-DWNANSLFPQQSCSKLWVAITTMDAVD -RGKVRLDSSVTLGRSDLTLHQPLREKILGGGTTLGSLLFDAITESDNTANDKLMRAVGGP -QAVRGMIARKGLGAIRFYNGERALQSRYISDPYDGASPHAIAGALAALKKGQLLSPASSS -RLLSIMGRTRTGGMRVRAALAPGWEWNHKTGTGQIAGLNDIGLLSAPDGSVYAMAIMVIA -NHS-DGSAQELMRDVTKAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D67B93 ---HLRKQVNQELAKQPGVFAVAFKDLGTGQEL-LIREREEFHAASTMKTPVMIEIYKQAA -QKRLSLDDSITIKTESIVDGSPYTYKYVGTKRTIDSLVYDMIIWSSNLATNLVIELA-DA -QKVTQTMREMGANDIQVRRGVEDSKA-FAQGLNNTTTAYDLMVIFEKIALGKAVSPAASE -AMIKTLLDQRF-KTKIPAKLPKDVKVAHKTGSIK-GVLHDSGIVFLPDGRKYVLVLLSKD -IQ-NEQAVENVMATVSKLIYDY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=UPI000D38E32F ------NAVQALGISFKGDVGISVRDIDEGWVV-AWEGNNPRPQQSVSKFWVAIAVMDAVD -RGRLSLTDPVTVTRSDLTVHQPIRAFVGKDGTTIGDLLRGAMTRSDNTCNDVLLWRIGGP -AAINRMLDEKGIAGVGFGPGERQLQARYLSDPLDGASANGVTLGLSLLAQGKLLSAQSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPVRMRLMGNVTRAIVA-- ->[subseq from] Metallo-hydrolase family protein n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520JEA4_SPHSX ---DLLNAVQALGAAFQGAAGISVRDIDEGWVV-SWEGDDPRPQQSVSKLWVAIAVMDAVD -RGQLSLADPVTVTRSDLTLHQPIRALIGKDGTTIGELLRGAMTRSDNTCNDVLLWRVGGP -AAINRMLADKRVAGVKFGPGERQLQARYLAAPMDGASANGITLGLSLLAQGKLLSARSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVVA-- ->[subseq from] Class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A5C8XA77_STAAU ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=UPI000B879046 ---RLVNAVQALGRGFKGAVGISVRNIDEGWVV-AWEGDRARPQQSVSKLWVAIAVMDAVE -HGRLSLADRVTVRRSDLTLHQPIRALVGKNGTTIGALLRGAMTRSDNTCNDVLLWKVGGP -SAINRMLREKGIDGVKFGPGERKLQARYLAAPMDGASANGVTLGLSLLAEGKLLTPRSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -THQPIPTRMRLMGNVTRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8WUY7_9BACT --qKLEATINDVDHNLDGVLAAAIMDLSTGQKY-LFHADEVLPTASSIKIAILAELYRQAQ -QGKVKLTDLYILQQSDLVGGSGIAEALTPGTLTIRDVAALMISVSDNSATNIIIDRV-GM -ENVNALLDSLGLTHMRLRRKMMDLKAAG-EGRENVASPREFMLLLEALYRGRVLNKQFTE -DFFKLLSVHKE--SYIPRELPEDLRVANKPGELE-GVRNDSGIVFTGSR-PFVISVMTTY -LRRE-RDGGDAIVRISTAAYRMf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI13_KLEPN ------------------------------------------------------------- ----------------------PVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLDNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAKATTLRKVLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAA----------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Hydrocoleum sp. CS-953 TaxID=1671698 RepID=A0A261KN50_9CYAN ---ALKTELDTVIAKYKLTPGVFMIDADTGAYL-DINGDTAVAAASTIKLPILVAFFQAVD -QGRIKLNDMLTMEESHVAEGSGDMQRKPGSKYTALQTARKMIVISDNTATNILIEALGGA -DVLNQLFQSWGLKNTVINNPLPDLSGT------NTTTPKDLINLISQVNQGGLVSLKSRD -RLFRIMERTRN-DSLLPRGVGRGSVVAHKTGNLKS-VLGDVGMIDLLNGKRYLLAVLVKR -PD-DDQDAVDLIRGVSKETYQY- ->[subseq from] Beta-lactamase class A n=1 Tax=Atelocyanobacterium thalassa (isolate ALOHA) TaxID=1453429 RepID=D3ER03_ATETH ----LKKQLESINTKYNVEPKAWFLDLDSNTYV-NFNGTKSIAAASTIKIPILVAFFEKVD -AGDISLDQMITMDKEIIVGGSGNMQYMETGKFTALEIARKMIIISDNTATELLIRQIGGK -LFLNERFKKWGMRQTVINNSLPDLDGT------NRTSPEDLAKLLLKIEKGNLISLRSRD -RFLNIMRETKT-KTLLPKGLERNASIAHKTGDIGT-IIADAGIIDMPTGRRYIGAIFVER -DY-DDPAGRELIQNFSKTIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=A0A196NEW7_9SPHN ---ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HQRLSLATPVTVTRADLTVHQPIRPLVGSSGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLLSHGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS -TRQSIPVRMRLMGDVTRAVIR-- ->[subseq from] Beta-lactamase class A BlaZ n=1 Tax=Cyanobacterium sp. HL-69 TaxID=2054282 RepID=A0A2K8WNL3_9CHRO ------------EKYANLQPSLFFVDLDNGAFV-NMNGMEAFPAASTIKTPILVAFFQDVD -EGKILLDEKLTMTEETKATEAGTMQYQPGTQYTALKVAEEMIIRSDNTATNMLIERLGGV -EALNQRFKEWGLESTVINNYLPDLEGM------NTISARDLAMTLVKVSNGDLVETRSRD -RLLGIMQRTIT-RTLLPQGIEPDAMIYHKTGDIGK-VLGDGGIIDIPTGKRYVGAVLVQR -PHND-YTARTMIQEISREAYQHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. HDW15B TaxID=2714943 RepID=UPI00140D3470 ---ALRDQLRTITRAFDGSSGIAIVSLRDGWEA-SWNGDKLFPQQSCSKLWVAITAMDAVD -RGRIRLSNKVTLTRDDLTLHQPIRQKILTGPTTLGALLFQAVTESDNTANDRLLRAVGGS -EAVRAMIARKGLGAIRFYEGERKLQSRYLTNPYDGAAPRAVANALARLKAGQLLSPTSTA -ELLSIMGSTRTGKLRVRAGLAPGWSWNHKTGTGQIGGINDIGLLTAPDGAIYAMSIMTVP -NRAD-GGAQDLMQAVARAVIAQ- ->[subseq from] Beta-lactamase n=5 Tax=Bacteria TaxID=2 RepID=X2L5P1_9BACT --tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK -QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT -HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL -WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD -SKLSSEKTEELIAEISRLTYEY- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas sp. 8AM TaxID=2653170 RepID=A0A654CP80_9SPHN ---ALQQRVTQLIRSFPGKAGAAIQAVDEDWIV-QEGGALYLPQQSVSKLWVAMTVLGQRD -AGRLKLDDPVLVTRDDLTLHQPVASLVTGEGTTVAGLLTRALTQSDNTANDRLLTYVGGP -AAVRRFLSEKRLPGIRFGPGERLLQSRYIDNPPDGAQPAAIVEALARLARGELLSETSTR -VLLETMANSHTGRARLKAATPVGWTLAHKTGTGQNAGFNDIGILTAPDGRRYAIAVQIGD -TTAPMRVRQVLIQQVAAAL---- ->[subseq from] Beta-lactamase class A n=2 Tax=Bacteria TaxID=2 RepID=A0A2T5GHJ2_9SPHN ---NLLNAVQALGISFKGDVGISVRDIDEGWVV-AWEGNNPRPQQSVSKFWVAIAVMDAVD -RGRLSLTDPVTVTRSDLTVHQPIRAFVGKDGTTIGDLLRGAMTRSDNTCNDVLLWRIGGP -AAINRMLDEKGIAGVGFGPGERQLQARYLSDPLDGASANGVTLGLSLLAQGKLLSAQSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPVRMRLMGNVTRAIVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Anaerospora hongkongensis TaxID=244830 RepID=A0A4R1PTQ9_9FIRM --kDIHAKLHAQLASFPGRCGLVIVNLANGEKW-EYCPETCFAAASMIKLPLMYEVMRQAA -AGLLSLDEYLTVTSEIQTGGAGILGELLPGLLTIRELVTLMIILSDNTATNMLIDRI-GM -DSVNNTAAALGLQSTILRRRMMDFEAA-ARGEENMTSAADLAQLFAHIYHPQLLSKEYGA -LMLDILKRQQV-RDKLPFYLPEEIEIAHKTGTLP-GVEHDGGILFLS--APYIICVLTDG -HTAN-YEGLQLVALIGKIIYE-- ->[subseq from] serine hydrolase n=1 Tax=Altererythrobacter soli TaxID=1739690 RepID=UPI001370938D ------------------------------------------------------------- ---------------------------------SALSLMDRMMVRSDNRATDLLIGALGGP -GAVDYWLRAQGLSGIRVDRNIAQLLGDRRWDIRDSSTPLAMLELLRLIDSDRALAPQSRA -LLLDMMRRCATGSNRIRGLMPYGAKVENKTGTLNQ-YTSDVGFLTLPDGRRVAVAFFARG -GE----NRPAVIATAARAIYDTf ->[subseq from] Beta-lactamase n=1 Tax=Cyanobacterium stanieri (strain ATCC 29140 / PCC 7202) TaxID=292563 RepID=K9YNW8_CYASC -----REKMTALFEKYHLQPSAFFVDLDNGAFV-NMNGIEAFPAASTIKTPILVAFFQDVD -EGNILLDEMLTMTEENRATEAGTMQYQPGTQYTALKVAEEMIIRSDNTATNMLIERMGGA -EALNQRFREWGLESTVINNYLPDLEGT------NTISARDLAITLMKVSNGDLVESRSRD -RLLGIMQRTIT-RTLLPQGIEPGATIYHKTGDIGK-VLGDGGIIDIPTGKRYVGAVLVQR -PHND-YTARTMIQEISREAYQHf ->[subseq from] Slr0121 protein n=1 Tax=Synechocystis sp. (strain PCC 6803 / Kazusa) TaxID=1111708 RepID=Q55897_SYNY3 --------------------YSYFIDVDNGQFA-NAKGETQLPAASTIKIPVAIAFFEAVD -QGKIQLHEELPLTQDVIVGEAGTMQYDVGKRYPALEVVTKMIVISDNTATNMLIKRLGGK -EFLNQRFQAWQMPQTKINNYLPDLEGT------NTTSPQDLALLLVKLQGGELLSLKSRD -RLLGIMQQTKT-RTLLPQGLEPDAQIAHKTGDIGT-VLGDAGIVDMPNGKRYVGAVLATR -PHND-VAGRLLIQDISRTAYQHy ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter sp. GH3-10 TaxID=2691582 RepID=UPI001365D5AE --dALSATFDRIGQEFGGSLGIAVVDVDTGWST-GFNQNALLPQQSVSKTWVTLTALEMAE -KGQLDLDSPIRVSREDLTLHQPIRKEILRMGTTIGELIERAIQKSDNTANNAILQRVGGP -AAVRAMLARNGLEGIRFGPGEKPMQSNYLADPVDGATPIGIARALARIERGEVLSEKRAE -EFLTIMSNTSSGPRRLKGGRADGWVISHKTGTGQQSGYNDVGVLFAPDSSAYAVAVMIGV -TERPTIQRMDMMQSVTRAVIA-- ->[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A231VM40_THETR ----LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK -EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN -MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN -LSTN-LDGRRAIGKISKMVYDEy ->[subseq from] class A beta-lactamase-related serine hydrolase n=1 Tax=Synechocystis sp. CACIAM 05 TaxID=1933929 RepID=UPI00138E7C84 --------------------YSYFIDVDNGQFA-NAKGETQLPAASTIKIPVAIAFFEAVD -QGKIQLHEELPLTQDVIVGEAGTMQYDVGKRYPALEVVTKMIVISDNTATNMLIKRLGGK -EFLNQRFQAWQMPQTKINNYLPDLEGT------NTTSPQDLALLLVKLQGGELLSLKSRD -RLLGIMQQTKT-RTLLPQGLEPDAQIAHKTGDIGT-VLGDAGIVDMPNGKRYVGAVLATR -PHND-VAGRLLIQDISRTAYQHy ->[subseq from] Beta-lactamase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2D8R0S9_9BACT ------------------------------------------------------------- ----------------------------------AYALMDRMMVRSDNRATDILINHLGGP -HAIEAWVESKGVTGMRVDRTIAQLLASKRWEHEDTSTPKAMLMLLHGIDRGGFLSASSRA -TILDMMRRCVTGRNRIKGLMPQGAIVEHKTGTLN-GYTSDVGYLTLPDGRRLAVAFFARG -GS----NRPAVIASAARSIYDGf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=A0A1H7FVD2_9SPHN ---RLVNAVQALGRGFKGAVGISVRNIDEGWVV-AWEGDRARPQQSVSKLWVAIAVMDAVE -HGRLSLADRVTVRRSDLTLHQPIRALVGKNGTTIGALLRGAMTRSDNTCNDVLLWKVGGP -SAINRMLREKGIDGVKFGPGERKLQARYLAAPMDGASANGVTLGLSLLAEGKLLTPRSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -THQPIPTRMRLMGNVTRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. UV9 TaxID=1851410 RepID=A0A4Q0GM86_9SPHN ---DLLNAVQALGAGFKGQVGISVRDIDEGWVV-AWDGDRPRPQQSVSKLWVAITVMDAVD -RGRLSLTDPVTITRADLTLHQPIRALVGKDGATIGELLRGAMTRSDNTCNDVLLWRVGGP -AAVNRMLADKGVVGVKFGPGERQLQARYLAAPIDGASANGITLGLSLLSQGKLLSTRSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPSGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAIVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V589_9BACT -------------------------------------------------VMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLAEFSAATIQYGDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPQAMAKSLQNLTLGKALAEPQRA -QLVEWMKGNTTGGASIRAGLPTTWVV---------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0011A6C11E ---ELQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RGRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGACIISKLSRVAYNHf ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium Isolate-002 (NCI) TaxID=2489215 RepID=A0A4Q0IZU1_9BACT --kAIEVALQEYIQEKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLEGf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Mn802worker TaxID=629773 RepID=UPI00056AA66A ------------------------------------------------------------- -------------------------------------VMELMIVRSDNQAADQLLAAVGGP -GVVQQWLDAHGFAGIRVDRTIAQLLRGHLADVKDVATPIAMVALLSRLEDATVLTARSSG -FLFGLMRRCSTGTRRIRALLPPGTTVEDKTGTLD-GVTNDVGFITMPDGHRVAIAIFARG -GR----DRQPGIAAIARLVYDRf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas phyllosphaerae TaxID=257003 RepID=UPI000684ED23 ---ALQARVSQLIRSFPGKAGAAIQAVDEDWIV-SEGGTLSLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVTRDDLTLHQPIASLVTVQGTTVGALLTRALTQSDNTANDRLLNVVGGP -SAVRRFLAEKRLNGIRFGPGERLLQSRYIDNPPDGAQPAGIVEALARLARGELLSETSTR -VLLETMAASHTGRARLKAATPAGWTLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD -TTAPMRVRQVLIQQVAAAL---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Curtobacterium sp. HSID17257 TaxID=2419510 RepID=A0A433FL51_9MICO ------------------------------------------------------------- --------------------------------LTVRALVDAALRQSDNTAANLLVERLGGV -GAVSRWLHGIGDDVTRVDRVEPDLNTAVPGDPRDTTTPAQSAADLRAVLLGDALDPDDRA -LLRSAMAGTTTGDGTIRAGVPDGWSVADKTGTASYGVRNDVAVVQPPGRDPIVLVVFTTR -DGAGAD----------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V588_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMCIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas jaspsi TaxID=392409 RepID=UPI0004B2CF1F ---ALNARIAEMGRAFDGKAGIAIVSLKDGWEI-GYGATALYPQQSCSKLWVAITAMDAVD -RGRVSLSDKVTLGRDDLTLHQPLADKILAGGTTLGALLFTAITESDNTANDKLMRSIGGP -SAVRTMIAAKGLGSIRFYEGERALQSRYVADPYDGAAPQSVARALARLKRGELLSAESTN -RLLSIMSQTRTGKLRVRAALPAGWSWSHKTGTGQIAGINDIGLLTAPDGTVYAMAIMTVT -NRS-DGNSQDLMQAVTRELVAY- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001446C780 ---ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD -AGKIRLDETLVMGRKHIVGGSGNMQYRVGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLQNTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSSTSEL -QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGIFVRR -PNHD-ARAKDFIRQVSQVVYGYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf231 TaxID=1736301 RepID=A0A0S9CHS2_9SPHN ---ALQERVAQLVRSFPGKAGAAIQAVDEDWIV-SQGGTLYLPQQSVSKLWVAMTVLAQRD -AGRLKLDDPVLVTRDDLTLHQPIASLVTATGTTVGALLTRALTQSDNTANDRLLTVVGGP -AAVRRFLADKRLNGIRFGPGERLLQSRYIDNPPDGAQPSGIVEALARLARGELLSETSTR -VLLETMAASHTGRARLKAATPAGWTLAHKTGTGQNAGFNDIGLLTAPDGRRYAIAVQIGD -TTAPMRMRQVLIQQVAAAL---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudochrobactrum sp. C_NA_101_V4 TaxID=683079 RepID=D1LFD3_9RHIZ ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPASWVVG--------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Geminocystis sp. NIES-3708 TaxID=1615909 RepID=A0A0D6AIW7_9CHRO ----LKNKFAELKAKYKLEPGAFFVDLDNGAYV-NFNGTSNFAAASTIKIPILVAFFQDVD -AGKIYLDEKLTTTSSNIGSGSGGMQQPVGTQFSAIHTVTEMIINSDNTATNMIIERLGGK -NELNKRFKEWGLDMTVINNPLPDLEGT------NTTNPRDLAMVLVKVNQGDLISLRSRD -RLLEIMRQTKT-RTLLPQGIEEEASIAHKTGDIGT-ILGDAGIVDIPTGKRYIGAVLVKR -PYND-YSARTLIQEISRTGYQH- ->[subseq from] OKP-A beta-lactamase (Fragment) n=1 Tax=mine drainage metagenome TaxID=410659 RepID=T0YJU6_9ZZZZ ------------------------LDLRTGLHA-SHRGGERFPMCSTWKVLAVAAMLQRVD -AGQERLDRRIRFDAHQLVSWSPVTERHVGGEMRVDALCAAALEISDNTAANLLLEALGGP -AAITRFARGLDDRVTRLDRYETALNEATPGDPRDTTAPDAMAGDLRRLLLGDAL------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D1LFC0_ECOLX ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- ------------------------ ->[subseq from] Putative beta-lactamase n=1 Tax=Bacteroides sp. CAG:443 TaxID=1262739 RepID=R6MMD2_9BACE --hTLESQIRQVTKSIRAQVGVAVI-IDGKDTV-TVNNDSRYPLMSVVKYPQSLAVAHFLH -QHNRPLSTEVFIAKEALYPYSPLRDEYPEGNLPISRLLEYTLQQSDNNACDILFEYIGGV -SYAERYIRSLGTECLAISKTEEQMYQAPESCYENWSSPLEMARLTDTLFSKELFPSDYQN -FIKETMLNCVTGENRLPQPLNTTARIGHKTGTSGRGGINDVGFVILPDGRRYSIAVLIKD -SKETMKATEKVIADISEIVYRY- ->[subseq from] Beta-lactamase n=1 Tax=cyanobacterium endosymbiont of Rhopalodia gibberula TaxID=1763363 RepID=A0A2Z5TLV6_9CYAN ------EKVASQEKYAKVKPQGWFIDLDNGNYV-NFNGDTSLSAASTIKIPVLVAFFEELD -AGRIYLDEMLTMDEEIITGGSGSMQQKPGTKFSALEAATKMIVISDNTATDMLVRRLGGK -EALNKRFKEWGLTKTEINNRLPDLEGT------NTTSPKDLVELLARVERGDLLTVRSRD -RLLGIMQKTRT-QTLLPQGLEQGAIISHKTGDIGT-ILGDAGIIDIPTGKRYIGAVFAER -SYND-VMGRMVIQDFSRTVYQHf ->[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Nostoc sp. NIES-4103 TaxID=2005458 RepID=A0A1Z4S8M9_9NOSO ---QLNSQIKVLMARYSIEPGMFFLDLDTGNYL-DFNGEKAFPAASTIKFPVLVALFQEVD -AGRVKLNETLVMRRDLMTGGSGVMQKRSGTRFSLLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRNWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALIANNQVLSNSSRT -QVLNIMRRVKN-RSLLPSGLGKGAVIAHKTGTLGV-ILGDAGIIEMPSGKRYLAGIIVKR -PFND-LRGKAFITQVSRLVYG-- ->[subseq from] class A beta-lactamase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012614F94 ------------------------------------------------------------- ------------------------------TDITLQTACQATMETSDNTAANLVLEKIGGH -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSASRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A3Z6_RAHAQ --------------------------------------------------MAASAILKESE -VKKNLLTQYVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIVGD-------------------------------- ------------------------ ->[subseq from] AMIN domain-containing protein n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000C7F941E ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIIVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI00125CC26A --tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK -QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT -HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL -WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD -SKLSSEKTEELIAEISRLTYEY- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides faecis TaxID=674529 RepID=UPI001106DDF3 --tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK -QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT -HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL -WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD -SKLSSEKTEELIAEISRLTYEY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2W6WY67_9SPHN -----VSIIQSLGRNFNGDVGIAVKRVDADWVV-AYNGSKLYPQQSVSKLWVAMNLLDNVD -RGKLRMSDTVTVTRSDLTLHQPLAAMVGKDGTTYNDLFRRAMTESDNTANDMMLRKGGGP -EAVRGYLARRFISTIRFGPGERLLQSAYLANPPDGAAPIGIVTALAKLKRGEMLSPNSTQ -YLLSTMAQAKTGPQRVKGGVPFGWHYAHKTGTGQSTGYNDVGIMTAPDGTSYAIAVMIGS -TTVAIPERWALMQAVSRAVAEN- ->[subseq from] serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=UPI00123AEC3F ----LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK -EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN -MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN -LSTN-LDGRRAIGKISKLVYDEy ->[subseq from] Serine hydrolase n=1 Tax=Fischerella thermalis CCMEE 5273 TaxID=2019663 RepID=A0A2N6KMV1_9CYAN ---QLNTQVKGLMARYSLQPGMFFLDLDTGNYL-DLNGEKIFPAASTIKFPILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIIVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae subsp. pneumoniae TaxID=72407 RepID=A0A0M3R6L4_KLEPN ------------------------------------------------------------- --------------------------KTPCRRHTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPKKKAKRIVVIYL-- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI000DEFE825 ------------------------------------------------------------- -------------------------------TLSAKTLMEAMLIHSNNVATDILIRNLGGP -RVVQEWIDFHRLSGIRVNRTIAQLLASPRDDIRDSATPEAMVTLLRQIDRGNVLTPQSRV -FLLSVMRRCATGSNRIRGLLDPTVLVEHKTGTLT-GLTSDVGFITMPDGRRVALALFARG -GS----DRPNSIAQAARTIYNGf ->[subseq from] serine hydrolase n=1 Tax=Citromicrobium sp. JLT1363 TaxID=517722 RepID=UPI001111BCFA ----LDDRLFALGTGLEGKIGIAVHDPARSRMM-HYNGTQLFPQQSVSKLWVALTALDQAD -RGELDLSETGTVRVDDLAVHNPIRRSVIANGTTYKDFLERALTASDNTANDMVLRRVGGP -DEVRKTLARKGFADIRFGPGERPMQSAYVADPVDGATPVAIASALARLHGGELLSQESTA -RYLAWLDDVKSGPNRLKGGLPDGWSIGHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR -TQVPVPARMDMMHGVVRAVAG-- ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus timonensis TaxID=1871002 RepID=UPI0008D9D216 --eQVKKRIASLCRQRAGTVAVDFYDETIGHGF-SFGGTRAVPSASTIKVLILAELLRQVE -QGLLSLEQPVTIRKEDYTGGDGILKELEPGHFTLKELATLMIIVSDNLATNRIIGLV-GM -ENVNALGKELGLQAARLGRRMMDSD-ALARGMDNWISAGDMGKLLRKIYEGTLVSQRASK -LMLDILKRQQQ-GERLQRYLPETVPLAHKCGDLD-GVENDGGIFLLPDH-PYILVVLTSH -MP-DNRSGRETIGRISRWVWE-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG22_combo_CG10-13_8_21_14_all_63_91 TaxID=2014312 RepID=A0A2H0DQ87_9BACT --eNMSAEIEKAARAYPARVAILIKDLNRGYTY-AYHADDLFPSASLIKVPIMVGVFDKIH -RGRLSLQSNLKLRRSTRMGGSGRLKWQRDGTFTVRQLLEQMMQRSDNTAMLLLIDEV-GM -GFLQNFFPTMGLVYTEIYPEGLRLTSG-RVRYENYTTAHEMAMLLEKAYKGKLVNSFASE -LMLDIMKGKK-GKTRLAKHLPVGWEIAHKTGLLRR-VCHDVGVVYSPNGD-YVVAVLTGR -NP-TYGRAKEFITEIGDITYKHy ->[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A2S5D179_LYSSH ----MQQTIQRLIQEAPYKVHMFVKDFKTNDFViHERLDDAFSSASLIKVPILIAVFDYID -VCNLPINQVITVTPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDLI-GM -DVLNQYFHKIGLTQTQLQRKMMDFER-LAKGIDNITTARDMALLFSRIYEKNLLSPVFSQ -LVIDILCRQRF-HENLRRYIVDDVTIAHKTGGLDS-VDHDVGIVYSHGQ-EYAIGVFITE -VKQN-DVARQLIGRLSKVVYDN- ->[subseq from] Beta-lactamase n=1 Tax=Anabaena sp. WA102 TaxID=1647413 RepID=A0A0K2M3K8_9NOST ---ELQTPIKTLMARYKLSPGIFFMDLNTGDYL-SINGDKSFAAASTIKYPILVALFQQVD -AGKIQLDETLVMGKKHIAGGSGNMQYRLGSKFSLLETATRMMTISDNTATNMIIERLGGI -TQLNQKFRSWGLQNTVMRNRLGDFQGT------NKTSAKDLVKLSALMENNQLLSNTSQL -QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGVFVQR -PNND-PRGTDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase class A n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A1H8JLL9_9BACI ----LQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKEHIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPNKGNFIISVFSIG -NN-TEAEGASIISKLSRVAYNHf ->[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A2G1CM45_THETR ----LYDDIKRFINSTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK -EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN -MMLDILKKQQD-LGRLDLYLPDDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN -LSTN-LDGRRAIGKISKMVYDEy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=D1LFB9_ECOLX ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Margulisbacteria TaxID=2211321 RepID=A0A2W4I0T0_9BACT ---------------NGGTVGISIKDLTSEEYI-SINGDIQFNPASVIKVPVMAEVFHQLA -NGKLTLDKCIVLKRNNKVPGSGGLYYCQNGNYTIKHLVEKMITESDNTATNMLINFV-GM -NNINKYMNSLGLSQTVIKDDTMLSKK---PGYQNTTTPDDMLLLLDMMYQGKLVNKKYSL -QMLEIMSAQKH-KWGIRKYLPETLKIANKTGSLNS-VRNDIGIIFVKDK-PYILTIFAKQ -IPSD-FEATLFVRTISKLIYDK- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8YZH2_9BACT ---KLRQQIEQELSKQPGVFAVAFKDLSTGAEV-LIREHEVFHAASTMKTPVMIEVYKQAA -QHKLALTDTMTITTESIVDGSPYSYKAVGTKRTLAALVYNMIIISSNLATNMVIERV-GA -QNVTQTMRDLGARDIQVRRGVEDSKA-FTKGLNNTTTAYDLMLIFEKIATGKAVSPEASK -AMITTLLDQKF-NDAIPGKLPKEVKVAHKTGSIT-GVRHDSGIVFLPDGRKYVVVLLSKD -IK-DDKATIETMATVSEMIYKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GPW8_9BACT ---ELRQQIEQELSKQPGVFAVAFKDLTTGKEL-LIREHEVFHAASTMKTPVMIEVYKQVA -QHKLSLKDSMTITTESIVDGSPYSYKAVGTKRTLAALVYDMIIVSSNLATNMVIERV-GA -QNVTQTMRELGAKNIQVRRGVEDSKA-FAQGLNNTTTAYDLMVIFDKIATGKAVSPDASK -AMITTLLDQKF-NDAIPGKLPKDVKVAHKTGSIA-GVRHDSGIIFLPDGRKYVLVLLSKE -IK-DDKATIQTMATVSEWIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Phenylobacterium sp. TaxID=1871053 RepID=A0A525JHA5_9CAUL ---DLQATLERIAAGYGEPVGIAVSDVSAGWMA-EVGGEETYPQQSVSKLWVALAVLQAVD -DRRLSLDQTVVMHQEDRSVYQPLASRIRGAGISLADLMRHALIESDNAANDMLIREVGGP -GVVAHAIAQKHLAGLALGGTERDVQTTYLANPPDGATPVGIATALSALKRGELLSRSSTD -FMLELMGEARTGVLRLHAGLEPGWSLAHKTGTGPSVGINDVGLLTAPDGRTYAVAVMVRQ -TKQPPSARHRLMAGVARAVESYw ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas hengshuiensis TaxID=1609977 RepID=UPI000980EF44 ----LLNAVQGLGGGFAGSVGIAVRDIDEGWLI-SFNGAAALPQQSVSKLWVAIAVMDAVD -RGALSLSDPVTVRRSDLTVHQPIRALVGPDGTNVRALLEGAMTRSDNTCNDVLLWKVGGP -TAIRAMLARKHIEGVTFGPGERELQARYLAAPYDGASAQGVTLGLSLLARGTLLSPASSA -HLIGLMRASRTGPARMRAGLKPGWALAHKTGTGQTTGYNDVGILTAPDGHRYAVAVMIAS -TRVSIPVRQRLMANVVRAVIR-- ->[subseq from] Uncharacterized protein n=1 Tax=Trichormus variabilis SAG 1403-4b TaxID=447716 RepID=A0A433UQF6_ANAVA ---ELQTPIKKLMARYKLSPGIFFMDLETGDYL-NVNGDKSFAAASTIKYPILIALFQEVD -AGRIKLDETLVMGRKHMVGGSGNMQYRVGSKFSLLETATKMMTISDNTATNMVIDRLGGI -NKLNQKFRGWGLQNTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSDTSEL -QVIGIMNGCHN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETPSGKRYLAGIFVRR -PNHD-ARAKDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. enrichment culture clone MS40-13 TaxID=979980 RepID=F1CKJ8_9PSED ------------------------------------------------------------- ----------------DLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSG--------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar1 TaxID=2004467 RepID=A0A1Y0GZN4_9BACT ----IEAKLAALEKTNKCEIGAAIVT-PTETHF--SRKNERFSLQSVMKMVVSMTALHLVE -RGKWKLDQPFTFRFSDLSIHQPLSDELGNRNVTLDQLIELSTTESCSASVDFMIRKMGGT -KVVNEFLKKHDIKGMSVDREERELQTRYQIDPRDTTTPAAMADLLKKLVQGKLLSPEHTA -YFMGVMERTQTGPDRLKAGVPDGWILGHKTGTSSRSATNDVGYVRNESGEWKIIVALIRN -SKQTYEVREATIRQVAEVAFE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas kaistensis TaxID=298708 RepID=UPI00143C4CF4 ------------------------------------------------------------- ---------------------------------SARALIESMMIKSNNQSTDLLIANLGGP -RAIQQWLDHNQIRGVRVDRNIARLLADKRWDLRDSSTPVAMVEMLRSLDKGNILTPANRA -YLLDVMARCSTGKNRIRGMLA-GVPIAHKTGTLNN-YTSDVGYLTLPDGRRLAVAFFARG -GT----DRPLTIAQAARTIYDGf ->[subseq from] HGE-1 beta-lactamase n=1 Tax=Clostridium sp. CAG:967 TaxID=1262849 RepID=R5KCJ4_9CLOT ----LSIKLNCLILNKDAVVGIAIIK--NQKEW-IIGSKNSLPMLSVFKYFVALKVLDKLE -KEKISLNKEITINKNMVDEYSQMLDKYKTFPISIANLLKYTISESDNNACDILIGYAGGT -KEIQEYINSIGFVDVEISETEFDMNKEIEKQYLNQARPIDIIRAMKFVRDRNILSDASCK -FLDEIMINTTTGKDKLKAGLPQNITLGHKTGSSSRKADNDTGYVFLPDGNVYYIAVMIKD -SKMSDEENAKLISSISKITYTHf ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. GBPx2 TaxID=2716263 RepID=UPI00140C11C0 --eDLKVAIQALIEDTEGDFGIAFKLLDSGSHL-LINEKEVFHAASTMKTPVMIEIFKQAG -SGKFSLDDSILIVNESIVDGSPYSYERIGEKATVYELMYQMIIKSSNLATNILIEEV-GA -ENVTQTMRDLGAADIEVLRGVEDLKA-FDAGLSNTTTALDMMLIMEAIASGEAVGQEESR -QMMDILYDQYY-KDLIPKLLPKEVKIAHKTGSIT-GVQHDAAILTLPDGKQYVLVILTKN -LT-DVEAGKEAIAEISKMIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium symbiosum TaxID=1512 RepID=A0A174H0T0_CLOSY --eELKNRINEFIESQTGNICVALFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC -AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM -DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA -LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG -VK-TNKDGREAIGRISQIIYEE- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYB2_FULL_48_7 TaxID=1797967 RepID=A0A1F9XK05_9BACT --------------SFPGEVGLYIKDLRTGVVV-AYNEDKKFASASLVKIPIMAAAYQAVE -DGNITLQEKLTLSQRLKASGSGMLKRFRRGTFTIDELLYHMITESDNTATNMITDKL-GY -GYVNWVFRNLGMQVTRMDRAIMDLRMR-SLGIENYTTAREMGEILEKIYNKKIISETACQ -DMLDILSHQKY-NDRIPRYLPEGLSVAHKTGLLR-GICHDAGIVFTPRGD-FVVCVLTSD -FG-SYRLAKNLIGEVAYKTYRAy ->[subseq from] Uncharacterized protein n=1 Tax=Blastopirellula marina TaxID=124 RepID=A0A2S8GMP6_9BACT ---ELSEALLPAIKRHKGEAAVLIKHLPSGATF-AYQADRPQGTASLIKLPVLMTLYKQVT -DGDVSLDALVEMKKEDQVPGSGILTGHFSPGLSVYDAAHLMITYSDNTATNLVIDQI-GL -PATKKLMKELGCPSTQLNSKVYRRDTSSQQYGLGVTSCSDMVRLLEMLHDGKFVDAATSK -KILAHLAFGDD-KSKVTRYLPAGVKPAHKTGAVNN-VRTDAGIIPLPEGA-LLFSVLTQN -NEGDKNEAELLAAEIGQVAYHYf ->[subseq from] Uncharacterized protein n=1 Tax=Blastopirellula marina TaxID=124 RepID=A0A2S8GMP6_9BACT ----------------------TVIDLDSGEAIgGADFDTVRDPASVTKIMTAHLVLTLAE -KSPEVLDETITFSERDKTPGST-SALKAGEKVSVGELLYGLMLPSGNDASVALAEHFGDI -AAMNKMAKSLGMTATGYANPHGLTAE------GHVTTAADMAKLARAAMQSERFRKIVAT -QQHATTVQSESGYERTNQLLEQEGFFGVKTGTTGPAGACLVSCCQRDGK-RLLMVVLGSS -STEA------------------- ->[subseq from] serine hydrolase n=1 Tax=Synechococcales cyanobacterium C TaxID=2690447 RepID=UPI00137A9656 ----VKAEVETLAAQSGLTPGAFFYSLDTGHFL-NLSGDRVFSAASTIKIPILIAFFQAVD -AGQVRLDESLVMRPDLIASEAGSIQYPPNSEYPALEIADLMITISDNTATNMLIDRLGGA -AALNQRFQSWGLQHTKIENLLPDLEGT------NLVSPMDLATVFLRLGEGELLSEASRT -KALEIMSRTVT-NTLLPQGLGEGASIAHKTGDIGS-VVGDAGLISTPNGQTYAAAVLVAR -PHND-SRAQELIRQISRITYTRf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CF311 TaxID=2135485 RepID=UPI000E31FE6E -------AIDGITRNFDGLVGVAVTSVQDGWIVtSNDAARPMPQQSVSKLWVTMTVLDQVD -QGKIRLEDPITITRADFTLHQPIAALVKGDQATVGEIVRRAMQMSDNTCNDKLLRLVGGP -DAIRAFLARKGIAGVRFGPGERLLQAAYVRNPPDGAAAGAISVALARLKRGELLSPTSTD -WLLRTMDGAKTGRARVHGAVPPGWIYGHKTGTGQTAGFNDVGILTAPDGKSYALAVMIGD -TRRPIRERQMLMQQVAQAIVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A3Y5_RAHAQ --------------------------------------------------MAASAILKESE -VKKNLLTQHVGLKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPAAWIVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. CF311 TaxID=2135485 RepID=A0A2U0VJ25_9SPHN -----VSAIDGITRNFDGLVGVAVTSVQDGWIVtSNDAARPMPQQSVSKLWVTMTVLDQVD -QGKIRLEDPITITRADFTLHQPIAALVKGDQATVGEIVRRAMQMSDNTCNDKLLRLVGGP -DAIRAFLARKGIAGVRFGPGERLLQAAYVRNPPDGAAAGAISVALARLKRGELLSPTSTD -WLLRTMDGAKTGRARVHGAVPPGWIYGHKTGTGQTAGFNDVGILTAPDGKSYALAVMIGD -TRRPIRERQMLMQQVAQAIVA-- ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. Z76 TaxID=2304565 RepID=UPI001368D1EE --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=D1LFB6_ECOLX ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVG--------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Gemmata massiliana TaxID=1210884 RepID=UPI00137B94C7 ---DLESRIAPLAKDHKGKVAVAVKHLKTGEEF-YLNADEAMPTASLIKLPVMVETYWQAH -EEKVKLDTKLTLTKDDKVGGSGILTSHFSDGFPLKDAVRLMIVYSDNTATNMVLDQI-GI -PSTNTRMEKLGLKNTKVHAKVFKGSTRTDKYGLGSTTAKEMVQLLELIETGKVASPEACK -EMLGHLKACDD-KEKMTRYLPAGTVVAHKTGSVN-ASKTDAGIVYLKSG-PVVLCVLTDG -NDDKDNAAQVLIGKIAKEVYEHy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A420_RAHAQ --------------------------------------------------MAASAILKESE -VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP -QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWVVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Synechocystis sp. (strain PCC 6714) TaxID=1147 RepID=A0A068MWC2_SYNY4 --------------------YAYFIDVDNGRFA-NAKGETQLPAASTIKIPVAIAFFEAVD -QGKIQLHEELPLTEDVIVGEAGTMQYDVGKRYPALEVVTKMIVISDNTATNMLIKRLGGK -EFLNQRFQAWQMPQTKINNYLPDLEGT------NTTSPQDLALLLVKLQGGELLSLKSRD -RLLKIMQETQT-RTLLPQGLEPDATISHKTGDIGT-VLGDAGIVDMPNGKRYVGAVLATR -PHND-VAGRLLIQDISRTVYQHy ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q7CLG2_9BACT --eKLEATINGVDRNLEGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAILAELYRQAQ -QGKIKLGDLYTLQSSDLAGGSGIAGALTPGVLTIRDVAVLMISVSDNSATNIIIDRI-GI -ENVNALLDSLSLTQTRLRRKMMDVKAA-GEGRENIATPREMVTLLESLYRGRVLNKPMTE -DFFTLLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGSR-PFAISVMTTY -LRRE-KDGGDAIVRIATAAYQMf ->[subseq from] Beta-lactamase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) TaxID=580327 RepID=D9TTD1_THETC ----LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIYKMAK -EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN -MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN -LSTN-LDGRRAIGKISKLVYDEy ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Thermokryptus mobilis TaxID=1643428 RepID=A0A0S4N168_9BACT --rKTFEKIKFIADTSNGVIGVAVKNLATGETF-LINENLIFPQGSAIKIPILIEVMKQAS -EGRFKLTDKIKIEKKHQVGGSGVLKEFADGLLSIYDLAVLMITVSDNTATNILIDLV-GM -ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPIEAMKLMEMLYKGEVISKDVSQ -KVLEILTKEKE--GSLGKYLPSDIKIANKPGGIE-GVNCEWGIVLLPRH-PYIIIVMSNY -NLK---SAQETIAQISKIVYEHf ->[subseq from] serine hydrolase n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DA651D ---ALNSQIRALMDRYNLVPGMFFLDLQTGDYL-NINGDKAFPAASTIKFPILIALFQEIE -AGRVSLDEPLVMRRDLVAGGSGMQDKSVGSRFTVLQTATKMMTISDNTATNMIIDRLGGQ -VILNQRFHSWGLQNTAIRNLLADVNGT------NTTSAKDLVKLSALITNNKLINNTSRA -QVLEMMRHCHN-QSMLPSGLGSGAIIAHKTGTLRF-VLGDAGIIQTPTGKIYLAGILVKR -PNHD-SRATAFIRQVSRFVYDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V595_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTNYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=3 Tax=Bacilli TaxID=91061 RepID=A0A160MD44_9BACI ---SLQDRLEEVLRDASGTFGVYVKHLETGETA-AINENRFFQAASVFKIPILAALYRDVH -LGKVNLQERIRLEEADLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKILRII-GK -ENVNQYMKEVGLNNTYIRFSCWELLCFQESIDNNVTTAFDMALLLEKIANKQLISEKACD -DMFEILEKQQF-RNRIPYLLPATTVVAHKTGTVAS-VVNDAGIVELPDNGRFIISAFSIG -NK-SEAEGARKIAELSRAAYGYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Rhodopirellula solitaria TaxID=2527987 RepID=A0A5C5X9A8_9BACT --kQLAKLILPLIRSHQGQVNVMLKHLPSGATF-AHQADSVSGTASLIKLPLLVTLYDEVD -NGRADLDAMITLQAKDMVPGSGILTTQFSPGLSLRDAAHLMIVRSDNTATNLVIDAI-GL -DSTNEKMKSLGLTETRLNSKLYRRRTRSKLYGIGSTTPAEMVSLLERLHENQLFDKATTK -QVTSHLYACDD-TTKFQRYLPAGARIAHKTGYVDD-IRTDAGWVETVDGT-MLYCVMTHD -NVSDQNSADLVIGEIGRIAYETf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas trueperi TaxID=53317 RepID=UPI0011522B17 ---ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HKRLSLATPVTVTRADLTVHQPIRPLVGPSGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRHMLKEKGVDGVEFGPGERELQARYLAEPYDGATANGVTLGLSLLAKDKLLSHASTE -RLSRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVIR-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013A6FC3A ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -TKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00129C4AFB --tSLQKQVEQLLEGKNVQVGIAVYY--QGKMLcTKNADQSFPMMSVFKLHQAVAILHCLK -QDSLTLKKPMLITKDMLSPYSPLRDKYPDGDLKVSQLIEYSVAQSDNNASNILFNLFDGT -HYANQVIQDLGCTNTQIKWTEDEMAMDHSRAYFNSTTPNDAILLLEMLVDNRTQRQQDFL -WLTEVMSGTQTGPNRLAKYLPTGTKLYHKTGTGYVKAVNDIGFVILPNGKHYSIAVFCKD -SKLSSEKTEELIAEISRLTYEY- ->[subseq from] Beta-lactamase-like protein n=1 Tax=Clostridium sp. MSTE9 TaxID=1105031 RepID=J0N280_9CLOT -----EEKIREYLNLQPGEQAVFIKDLTDGETF-CFNEKAVFPSASTIKLVIMACLLDQVK -TGRLSLEDPVVLTEEMRTGGDGILKELSAGHFSLREILTLMIIVSDNTATNILIQLL-GM -DAINEMAGRLRLSRTVLGRRMMDSEA-RKQGKDNYTCADDIAHILELIYEQKCVDVPSSR -LMLDILRRQQQ-SGRLQLYLPEEVEIAHKCGDLDF-LEHDAGIILLPKR-PYLIVVLTRD -NP-TNKDGREVIGTVSRMVYEE- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Elusimicrobia bacterium RIFOXYD12_FULL_66_9 TaxID=1797972 RepID=A0A1F9YKV6_9BACT ----MIADLDKLSSRYPGRVSIFLRDLRTGKTW-MHHPDDLFPAASLIKVPILIAAFYKMK -DGQLSLDEKLTISRRNRVGGSGSLKWRPDGTLKVRDLLLYMINESDNTATKMILERL-GL -GYVQQQFPRMGLLYTGIYEEGMSLKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKASSE -YMMEILKHPKAAQSRLAKGLPTGWEIAHKTGLLRQ-ACHDSAIFLTPNGD-YTMTVLTGQ -NQ-SYSQAKTLITKLAHVTFANy ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. MBR 210 TaxID=1881015 RepID=A0A1C0VNW7_9NOSO ---QLRSRVQALATKYSLDPGLFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEID -AGRIKLNETLVMRRDLITGGSGEFQKRAGTRFSLLETATKMITISDNTATNMIIDRLGGK -ARLNPRFRSWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVANNRLLSDSSRG -RVLNIMQRVRN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR -PFNDL-KARDFINQVSRIVYG-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A3N2L6S1_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA9971 TaxID=2055776 RepID=A0A353QTI9_9CYAN ---NLTNQLKYLAAAYQLETGIFIWDYNTGGYV-DINGDKIFPTASIIKLPVLFQIFRRSE -KGLINLNDKISLTNYYITGGSGSLQYSPGTKHTYRHLAALMIQESDNTATNMLLSSVGGM -NELDREIKNWGLKSTSLSNWLPDLDGT------NVSTPREMGTLLYNIGNTNLLSIKTRA -EIVDIMSHVRN-NRLIQAGLPADAGFIHKTGDIGT-MLGDAGVVALPDGRKYVIVIMVKR -PWNS-FAAKEFIIEASKITYNSy ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas pokkalii TaxID=2175090 RepID=A0A2U0SIU5_9SPHN ---ALVNRLSEVARNFDGVVGIAVTSVDRNWTA-SQGGARRLPQQSVSKLWVAMTVLDQVD -QGRIRLSDPLVITRADFTLHQPVASLVKGDQSTVGEIMRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLLSTMQASHTGKHRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSFALAVMIGD -TPRPINERQLLMHAVVRAVVAE- ->[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A223HXB4_THETR ----LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIYKMAK -EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSN -MMLDILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLENCQ-YIISVMTNN -LSTN-LDCRRAIGKISKMVYDEy ->[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium SM23_72 TaxID=1703777 RepID=A0A0S8ILD3_9BACT --sKLSQEISQEISQFKGKVGIVIKDLDKDWEL-FYNKQMLFPSASLAKVPLMAASFLAAQ -EGRLKLERNVKLKSSDKFSGSGILKDHPGVEFSVEELIGLMIYDSDNTATNMVTGMV-GI -NYLNNFFKNIGLKNTNLARRIADYSSR-KRGIENYTTAEDMAWILEKIYRKTLINKDISE -RCLKLLKLQRY-NDRIPKYLPVELTIAHKTGLER-GICHDTGIVYTPKGD-FLICVLTKH -ENANSVPSKEFIAKISLYVYHYf ->[subseq from] Uncharacterized protein n=2 Tax=Calothrix desertica TaxID=32056 RepID=A0A3S1CGC0_9CYAN ----LNSQIRALMSRYSLSPGMFFVDLQTGDYI-DINGNKVFSAASTIKLPILITLFQEIE -AGRVRLDDTLVMRRDLVAGGSGDMQNMRTGKFTVLETATKMMTISDNTATNMIIDRLGGF -SRLNERFRSLGLQKTALRHLLADEYG------TNTTSAKDLVHLSSLIANNQILSDGSRA -QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVKR -PNHD-KRATAFIRQVSHIVYDY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Gemmata sp. SH-PL17 TaxID=1630693 RepID=A0A142XHT1_9BACT ---DLESRIAPLAKDHKGKVAVAVKHLKTGEEF-YLNADEAMPTASLIKLPVMVETYWQAQ -EGKVKLDTKLTLTKDDKVGGSGILTSHFSDGFPLKDAVRLMIVYSDNTATNMVLDQI-GI -PSTNTRMEKLGFKNTKVHAKVFKGSTRTDKYGLGSTTAKEMVQLLELIEAGKVASPEACK -EMLGHLKACDD-KEKMTRYLPAGTVVAHKTGSVN-ASKTDAGIVYLKSG-PVALCVLTDG -NDDKDNAAQVLIGKIAKEVYEHy ->[subseq from] Beta-lactamase n=1 Tax=Altererythrobacter xiamenensis TaxID=1316679 RepID=A0A1Y6F7K3_9SPHN ----FERRIAQLADGTRGRIGVYAIDLSSGDEV-SVLGDQFFPMASTSKVAVAATYLAGVD -EGRWGLTSEWQLPR------------RGGAHVPAYRLIELMISKSCNDCTDALLDAVGGP -AAVNAWVKKAGISGFNLNRNIRALIRASVVDTRDAATPRAMGQLLAGIYQGRWLSSSSRQ -VILDSMEQTTTGKRRMRSAVPLSAKLAHKTGTLSR-TASDIGIFHTPDGRPIAVAIYVTG -QSPSMAVEN-------------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. LM7 TaxID=1938607 RepID=A0A1S6FL18_9SPHN ----LVTSIDSITRNFAGLAGIAVTSVDDGWIAsNATASRPLPQQSVSKLWVAMTVLDAVD -RGTVRLDDPLTITRSDFTLHQPIAALVKGDVTTVGEIMRRAMQMSDNTCNDKLLRLVGGP -QAVRDFIARKQLGTIRFGPGEKLLQAAYIKDPPDGAAPIAIADSLARLQRGELLSPNSTA -WLLATMGGAKTGKARVRGAVPPGWLYGHKTGTGQTAGFNDVGILTAPDGRSYAVAVMIGD -TARPIRERQLLMQAVASAIVAH- ->[subseq from] serine hydrolase n=1 Tax=Clostridium jeddahense TaxID=1414721 RepID=UPI0004BB4233 -----EEKIREYLNLQPGEQAVFIKDLTNGETF-CFNEKAVFPSASTIKLVIMACLLDQVK -TGRLSLEDPVVLTEEMRTGGDGILKELSAGHFSLREILTLMIIVSDNTATNILIQLL-GM -DAINEMAGRLGLSRTVLGRRMMDSEA-RKQGKDNYTCAGDIAHILELIYEQKCVNVPSSR -LMLDILRRQQQ-SGRLQLYLPEEVEIAHKCGDLDF-LEHDAGIVLLPIR-PYLIVVLTKD -NP-TNKDGREVIGTVSRMVYEE- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8W2V0_9BACT --qKLEATINGVDRNLEGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAILAELYRQAQ -QGKIKLGDLYTLQSSDLAGGSGIAGALTPGVLTIRDVAVLMISVSDNSATNIIIDRI-GI -ENVNALLDSLSLTQTRLRRKMMDVKAA-GEGRENIATPREMVTLLESLYRGRVLNKPMTE -DFFTLLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGSR-PFAISVMTTY -LRRE-KDGGDAIVRIATAAYQMf ->[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A410MP42_LYSSH ----LQESLEKIIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKEHIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGASFISKLSRVAYNHf ->[subseq from] Peptidoglycan glycosyltransferase n=2 Tax=Fischerella sp. NIES-4106 TaxID=2005456 RepID=A0A1Z4TF85_9CYAN ---QLNTQVKALMARYNLQPGIFFLDLDTGNYL-DLNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVMRRDLMTGGSGTLQKRPGIKLSVLETATKMITISDNTATNMIIDRLGGK -ARLNQRFQSWGLQNTMIRNLLGDFKGT------NTTSAKDLVRLGALLSNNQLLNDGSRS -QALDIMRHVKN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] class A beta-lactamase n=1 Tax=Parabacteroides johnsonii TaxID=387661 RepID=UPI00101D8EF0 --kAIENALQEYIKGKDARIGIAII-INGKDTV-SVNGNRDFPMMSVVKFPLALTVANWVD -TNNMSLSDTVTFSGKSLKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLNCVGGV -SGATSKMRQIGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFNNEMRNASQSYS -EISVMLKQCRTGLDRLALLLPTNATIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SGYDMAATSAIIAEISKIVWK-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZLY8_9BACT --kKLETRVREIADRLDGVVGVAILDLTDGRAL-LHNADRVFPTASSIKIAILLELYRQDQ -KGKAKLDDVYTFNPKDLVDDSRIMAGLTAGVVTNRDLAQFMVAVSDNAAANILIDRV-GR -DKVNAMLQGLGLSKTLLRRKMMDIAAAKRG-DENVATPHEVVRLLDAIQKEKVLNNESTA -QFIKQLSTKK--DSYIPRYLPDDVQVANKPGDLE-GVRNDSGIVYAKNR-PFAISVMTAY -DR-DEKAAERAISELALEAYHYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A729_RAHAQ --------------------------------------------------MAASAILKESE -VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP -QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPAAWVVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=2 Tax=Synechococcus sp. (strain ATCC 27167 / PCC 6312) TaxID=195253 RepID=K9RYG3_SYNP3 ---QVEKTIQQWAAKKQLQGGAYFLNLTTGNSV-NVDGTQIVAAASTIKIPVLVALFQALD -RGEITLAEPLTMRPDLIAGEAGTMQQKPGTKFSTLETAELMISISDNTATNMLIDRLGGA -TILNDQFVQWGLEHTVIRNPLPDMEGT------NTTSPKDLAILMARIAQGDLVSQTSRE -KLLGIMRTTVT-NTLLPQGLGPGAKIAHKTGDIGT-FVGDAGLIEMPNGQQYVAGIMVKR -PYND-PQGTELIRQISRLTYQAy ->[subseq from] Serine hydrolase n=1 Tax=Anabaena sp. MDT14b TaxID=1710886 RepID=A0A1B7WLX7_9NOST ---ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILVALFQEVD -AGKIQLDETLVMGRKHIVGGSGNMQYRVGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLENTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLLSSTSEL -QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGIFVRR -PNHD-ARAKDFIRQVSQVVYGYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9K5B2_9BACT -hsELEGELDRVADRLDGVVGYAIKDFSTGEAF-YRNADLVFPAASSIKLAVLLELTRQAQ -EGKLSLDEKHTVRRSETVAGDPILYMLGDGTMTLRDLAVFMVVLSDNSATNILIDRV-GM -ENVNAGVARLGLKETRLRRHMIDIEAA-RRGNENVSTPRELAVLLEKVRNGQVLDSVHSQ -DYFSILRLPKD--SLFSKALPPGVPVEDKPGALD-AVRCDAGIIEAEGH-PFVVSVMTTF -LA-SNEEGERAIKEIARLAYAHf ->[subseq from] hypothetical protein n=1 Tax=Phormidesmis priestleyi TaxID=268141 RepID=UPI0009ECD0B4 -----KNDIQTLVAQQQLNSSVMLVDLDTNAFL-NINASVALPCASTIKLPVLVAFFQDVD -AGKIHLDELLTMRPDLIATESGEMQYQPPGTFTALETATKMITVSDNTATNMLIDRLGGK -DVLTQRFQSWGLTSTAIRNPLPDIAGT------NTSSSQDLVTALGLVTNGKLMSLRSRD -RLLDIMRRTAN-SSLLPTGLGEGATIAHKTGSIGT-LIGDVGVVDMPSGKRYLIGALVKR -PR-DDERAEELIRKVSRLTYQYf ->[subseq from] Beta-lactamase/transpeptidase domain-containing protein n=1 Tax=Anabaena sp. 90 TaxID=46234 RepID=K7W3G2_9NOST ---ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD -AGEIQLDETLVMGRKHIVGGSGNMQYKVGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLENTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLVSNTSEL -QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGVFVQR -PNHD-ARAKDFIRQVSQVVYGYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A2E1YY57_SPHSX ---ALTAIIQSAVRNFDGKAGVAVESVDDGWIV-SANGETLMPQQSVSKTWVAMTVLAQRD -EGRLSLDDPLTITTADLTLHQPIAALVQKNGSTVGEIMKRALTMSDNTCNDKLLWLVGGP -PAVRAFIESRKLGAIRFGPGERLLQSAYIANPPDGAAPVAIADALARLKRGELLSAGSTS -WLITTMQSSHTGRNRLRGEVPGDWLFGHKTGTGQTAGYNDVGILTAPDGRSYTVAVMIGD -TARTIPQRWELMHTVVKAIVN-- ->[subseq from] Beta-lactamase class A n=2 Tax=Tissierella praeacuta TaxID=43131 RepID=A0A1M4TR86_9FIRM -------------DSVDEEVSIIIKDLTNDRWIlKYNEDRVFPSASLIKIPIMIEVLERVE -KGELSLDKKIKIKAIDRVDYSIISELTLK-EYTLIDLITLMIILSDNTATNVLIDLL-GY -EKVNETVKKLNCNNTILKRKMMDFTAA-KEGRENLTSPMDMALFMEKIYNKSIISPKICD -VMIDILTRQKH-RDMLPRYILDEVKIANKTGELS-GINHDIGIFYLENIN-YLIGIFTTN -GK-DDLVGKRTIGRISKLVYDNf ->[subseq from] serine hydrolase n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI00035CE78C ----LNSQIRALMSRYNLSPGMFFVDLQTGDYI-DINGDKVFSAASTIKLPILITLFQEIE -AGRVRLDDTLVMRRDLVAGGSGDMQNRVGKKFSVLETATKMMTISDNTATNMIIDRLGGF -SRLNERFRSLGLKNTALRHLLADVYGT------NTTSAKDLVHLSSLIANNQILNDGSRT -QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVKR -PNHD-ERAIAFIRQVSHIVYDY- ->[subseq from] serine hydrolase n=1 Tax=Tissierella praeacuta TaxID=43131 RepID=UPI001047B974 -------------DSVDEEVSIIIKDLTNDRWIlKYNEDRVFPSASLIKIPIMIEVLERVE -KGELSLDKKIKIKAIDRVDYSIISELTLK-EYTLIDLITLMIILSDNTATNVLIDLL-GY -EKVNETVKKLNCNNTILKRKMMDFTAA-KEGRENLTSPMDMALFMEKIYNKSIISPKICD -IMIDILTRQKH-RDMLPRYILDEVKIANKTGELS-GINHDIGIFYLENIN-YLIGIFTTN -GK-DDLVGKRTIGRISKLVYDNf ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI00084A423A -----QQTIQRLIQEAPYKVHMFVKDFKTNDFViHERLDDAFSSASLIKVPILIAVFDYID -VCNIPINQVITVTPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDLI-GM -DVLNQYFHKIGLTQTQLQRKMMDFER-LAKGIDNITTARDMALLFSRIYEKNLLSPVFSQ -LVIDILCRQRF-HENLRRYIVDDVTIAHKTGGLDS-VDHDVGIVYSHGQ-EYAIGVFITE -VKQN-DVARQLIGRLSKVVYDN- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G5G9_9BACT --eHVQRQLRDVASSFDGVMGYDVVDLTDGRTF-GALQDDVFPTASSIKLALIYELFKQVD -EGRIALEDVRPLNPAFKVGGSGVLHELTTPSLSIRDYATLMVVLSDNTATNVLIDAV-QM -TRVNDRMTALGLGHTKLRRRMMDREAALRGD-ENVSTPAELAKLLQIMYRGDGLTPASRD -TLIAILKKSKD--TPLRRGVPPNVDVANKPGDLE-GVATDAGIVYVKNR-PYVLAVMTSY -AN-DGGGGARAIEAASRAVYDYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. CCH5-D11 TaxID=1768786 RepID=UPI0009E97EB8 ---ALLNAVQALGRGFSGDVGISVRDIDEGWTV-DWAGDKPRPQQSVSKLWVGITVMDAVD -RGRMSLSDPVTVRKSDLTVHQPIRPLVDSDGTKVGALLQGAMTRSDNTANDVLLWRAGGP -EAVRRMLEEKDVAGVTFGPGERLLQARYLADPEDGASANGVTLGIALLAQGKLLSPASTD -KLLSLMRASRTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQSIPSRMRLMGDVSRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4RXL7_9CYAN ----LNSQIRALMSRYNLSPGMFFVDLETGDYI-DINGDKAFSAASTIKLPILITLFQEIE -AGRVRLDDTLVMRRDLVAGGSGDMQNMRTGKFTVLETATKMMTISDNTATNMIIDRLGGF -SRLNERFQSLGLQNTALRHLLADEYG------TNTTSAKDLVHLSSLIANNQILSDGSRT -QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVKR -PNHD-ERATAFIRQVSHIVYDY- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura rayongensis TaxID=1429076 RepID=UPI001355D5BA ---KALDELARRAEARGGVLGVVVQG-ASGERA-SVNADRTFTAASLIKLPVLLALLDGVE -AGRWSLDDRLPVR--DRVGGAGILRDLADVALSVRDLVSLMIVISDNTAANLLIDRI-GQ -HTVADWCARHGLHATVLARRMMDAEA-RERGEENRTSPADMATLLDGLVRGTLLGPAATA -FALDVLARQQV-RDRLPRDLPDNVRIAHKTGELD-GIRHDVGVIFTN--TPIVVAALTEN -TE----EADDLIAETARRAVQ-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 22-7 TaxID=2709707 RepID=UPI0013D14A57 ---SLKDRLEEVLRDASGTFGVYVKHLETGETA-AINENRFFQAASVFKIPILAALYRDVH -LGKVNLQERIRLEEADLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKILRII-GK -ENVNQYMKEVGLNNTYIRFSCWELLCFQESIDNNVTTAFDMALLLEKIANKQLISEKACD -DMFEILEKQQF-RNRIPYLLPATTVVAHKTGTVAS-VVNDAGIVELPDNGRFIISAFSIG -NK-SEAEGARKIAELSRAAYGYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A0P0LKQ2_BACVU --kTIEKALLEYVSDKDARIGIAVI-VNGTDTV-SVNGKRDFPMMSVVKFPLALTVVQWID -ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTIRELLEWSLVESDNNAADILLNHVGGI -SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAQLFDRFDTEMRNTSLSYS -EIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGERYSIAVFVAD -SGYDMAETSAIIAEISRIVW--- ->[subseq from] serine hydrolase n=1 Tax=Pseudanabaena sp. PCC 6802 TaxID=118173 RepID=UPI0012E9995F ---ALTAKIKQLAAESDLSLQTLVFDADTGVYT-DVNSRKPIASASIIKIPLLIAFLQDVD -EGKVQLGEQLEISKDVIVGEAGGLQYEPEGTISALETLTEMIVHSDNTATNMIMKRIGGK -DAANRRFKSWGLNSTVIRNQLPDLEGT------NTTSPYDLVNLLSMVDKGKLLSPRSRD -RLMDIMRRPVT-NTLLPQGIAADARIVHKTGDIRS-VVGDAGIIDMPSGRRYIMAAIVKR -PDND-QRANELIRQVSRATYDY- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A520VEU9_9SPHN ----LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD -ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP -SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] Beta-lactamase n=6 Tax=Sphingomonadales TaxID=204457 RepID=A0A2D5F3P5_9SPHN ----LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD -ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP -SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] serine hydrolase n=1 Tax=unclassified Erythrobacter TaxID=2633097 RepID=UPI0007B87384 ----LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD -ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP -SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. HI0028 TaxID=1822227 RepID=A0A176E195_9SPHN ----LEQQIAQLADGSDGRIGVYAIDLSTGREV-GVLADQRFPMASTSKVAIAATFLAGVD -ANRWSLTSEYRLPR-------------PGGALPAYRHLSLMISKSCNDCTDALLAAVGGP -SAVNKWMKDAGIEGFSLSRDIATLIRAWSVDIKDSATPRAMGQLLAGIYQGKWLSDYSRR -VLLDAMEETTTGKRRMPSALPVSANLAHKTGTLAR-TASDIGIFHTPDGRAIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Duncaniella sp. TLL-A3 TaxID=2530391 RepID=A0A4Z0V2U1_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNFPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044788EE ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Nostoc piscinale CENA21 TaxID=224013 RepID=A0A0M4SVF1_9NOSO ---QLRSRVQALASRYSLDPGLFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEID -AGRIKLNETLVMRRDLITGGSGEFQKRAGTRFSLLETATKMITISDNTATNMIIDRLGGK -AKLNPRFRSWGLQNTVVRNLLGDFKGT------NTTSAKDLVRLSALVANNRLLSDSSRG -RVLGIMQRVHN-TKLLPAGLGKGAVIAHKTGTLGI-VLGDAGIIQMPSGKRYLAGIFVRR -PFNDL-KARDFINQVSRMVYG-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas trueperi TaxID=53317 RepID=A0A543M1U1_9SPHN ---ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HKRLSLATPVTVTRADLTVHQPIRPLVGPSGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRHMLKEKGVDGVEFGPGERELQARYLAEPYDGATANGVTLGLSLLAKDKLLSHASTE -RLSRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVIR-- ->[subseq from] Uncharacterized protein n=2 Tax=Alistipes sp. An116 TaxID=1965546 RepID=A0A1Y4U656_9BACT ---TLEQDLEQLAASLEARIGIAIR-TPDGETI--SRQDVPLPLLSVFKFPVALAVLDKAD -AEGTPLTTPVEVGPEWLDPYSPLRDSLPATGVTLGELLRYSTSLSDNIACDRLLEYVGGP -NAVEHYVEKAGIEGFRIAATERTMHLDPANQRINVARPSAVCALFARLLEGGLLTPEHEA -LLQRLLEGAVTGTDKLRAGLPEGAVLGHKTGLSDRTADNDAGYVVLPDGRHYCVTVLVTD -SPADDAKNAAVIAAISKRIYEHf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium CG1_02_49_10 TaxID=1805289 RepID=A0A1J4VRZ7_9BACT --------VKEVSSAFSGEAGIVVRDMKGGYEI-VIDGDKPFPSASLAKAPIMAAYLLAAE -EGRVCLDETIRLKGYHKVGGSGVLKGVKTGKFTVEQLMELMITKSDNAATNMLIERL-GF -DYLNDAFKRLGLRNTNISRYMMDFKKR-SKGIENYTTANDVDLLLSDIYNGRLINKEVSD -RCMGLLKEQKM-ADRIPARLPPSTVVAHKTGLEK-GICHDAGIVFAPKGD-FAVTVLTRH -HNKDSRPSKKFISQIAFMVYTIy ->[subseq from] Beta-lactamase class A n=1 Tax=Gloeocapsa sp. PCC 73106 TaxID=102232 RepID=L8LQ12_9CHRO ---SLNQKIRDLTAKYQLDARAFFIDLDNYAYV-NFQGDTPISAASTIKIPILVAFFQDVD -AGKIYLDELLTMEEKHRAGGSGEMQYLGSGRFTALKIALNMIVTSDNTATNMLIERLGGA -EALNQRFQAWGLKSTVIRDILPDLEGK------NTTSPQDLVFLLGEVNAGKLISLRSRD -RLLDIMTATKN-NSLIPQGLEGDATVAHKTGDIGS-VLADGGIIDIPSGKRYLAAIMVKR -PHND-PQARTLIQEISRTAYQHf ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Bacillus firmus TaxID=1399 RepID=A0A380XTL2_BACFI ---SLQDRLEEVLRDASGTFGVYVKHLETGETA-AINENRFFQAASVFKIPILAALYRDVH -LGKVNLQERIRLEEADLVNGSGIFKELIPGIVTIKNLATMMVIVSDNVGTDKILRII-GK -ENVNQYMKEVGLNNTYIRFSCWELLCFQESIDNNVTTAFDMALLLEKIANKQLISEKACD -DMFEILEKQQF-RNRIPYLLPATTVVAHKTGTVAS-VVNDAGIVELPDNGRFIISAFSIG -NK-SEAEGARKIAELSRAAYGYf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. TaxID=1042 RepID=A0A3B9B5H0_9SPHN ----LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD -EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP -SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR -VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Beta-lactamase n=2 Tax=Erythrobacteraceae TaxID=335929 RepID=A0A2D9PA32_9SPHN ----LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD -EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP -SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR -VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. SAORIC-644 TaxID=1869314 RepID=A0A2K1EB22_9SPHN ----LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD -EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP -SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR -VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A2D9XBS1_9SPHN ----LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD -EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP -SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR -VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Putative beta-lactamase n=1 Tax=Parabacteroides sp. D13 TaxID=563193 RepID=C7X4B2_9BACT ----IENTLQEYIAGKDARIGVAVI-INSKDTV-SINGNRDFPMMSVVKFPLALTVAHWID -NNDMSLNDSIAFGENDLNEYSPMLKMYGKSRMTVRELFEWSLVESDNNAADILLKRIGGT -SGATSLMRQLNISEILIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYIEMRNTSRSYS -EISSMLEQCSTGRDRLAVLLPTNATIGHKTGTGFISAVNDCGYVKLPDGTRYSIAVFVAD -SGYDMGATSAIIAEISNIVWK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sartorii TaxID=671267 RepID=A0A4V3RT29_9BACE --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGALEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11) TaxID=858215 RepID=F6BKP3_THEXL ---SLHDDIMNFVSNAGGDIGVSVKNLKTGEMI-GVNEEMMFPSASTIKILIMAQIYKMAK -EGYIRLTDNIVLSDFMKTAGSGVLYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGLFHTKIQRKMMDFE-AIKSGKDNYTCPKDMTRLLEQMYSGKVVDEEYSI -KMIEILKKQQD-LGRLDMYLPDDVLIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN -MNT-NLDGKMAIGKISKMVYDEy ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001445C7A2 ---ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD -AGEIQLDETLVMGRKHIVGGSGNMQYKVGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLENTVMRNRLGDFKGT------NKTSAKDLVKLSALMENNQLVSNTSEL -QVIGIMNGCRN-RSLLPSGLGSGAKIAHKTGTLRF-ILGDAGIIETSSGKRYLAGIFVRR -PNHD-ARAKDFIRQVSQVVYGYf ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000708D1E0 --kTIEKALLEYVSDKDARIGIAVI-VNGTDTV-SVNGKRDFPMMSVVKFPLALTVVQWID -ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTIRELLEWSLVESDNNAADILLNHVGGI -SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAQLFDRFDTEMRNTSLSYS -EIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGERYSIAVFVAD -SGYDMAETSAIIAEISRIVW--- ->[subseq from] Serine hydrolase n=3 Tax=Clostridiales TaxID=186802 RepID=A0A413JG06_CLOSY --eELKNRINEFIESQTGNICVSLFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC -AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM -DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA -LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG -VK-TNKDGREAIGRISQIIYEE- ->[subseq from] Serine hydrolase n=2 Tax=Okeania TaxID=1458928 RepID=A0A6B3P403_9CYAN ---ALKTELDTVIAEYKLTPGIFLIDVDTGAYL-DINGNVAIAAASTIKVPILVAFFQAVD -QGRIKLDDMLTMEESHVAEGSGDMQRRPGTKYTALQTATKMIVISDNTATNMLIETLGGS -EVLNQLFQSWGLKNTTINDSLPDLSGT------NTTTPKDLINLISQVNQGGLVSLKSRD -RLFRIMERTKN-DSLLPRGIGRGTIIAHKTGNLKS-VLADVGMIDLLNGKRYLLAVLVKR -LD-DEQTAVDLIRDVSKKTYQY- ->[subseq from] Serine hydrolase n=1 Tax=Merismopedia glauca CCAP 1448/3 TaxID=1296344 RepID=A0A2T1C189_9CYAN ----VNAEIRSLMNRYKLSAGMFFVDLQTGEYI-DINGDRAFSAASTIKFPILMALFQEIE -AGRVSLSEPLVMRRGLMVGGSGNMSNKPAGTFTVSDTVNKMMIISDNTATNMIIERLGGK -NVLNQRFRSWGLQSTVIRNWLVDEKG------TNTTSAKDLVQLSALLANNKLVSDRSRL -MVMDIMRQCHN-RSMLPAGLGSGAVIAHKTGTLRF-VLGDAGIIQTPSGKTYLAGIMVRR -PNHD-RRATSFIRQVSQLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium baderi TaxID=1332080 RepID=UPI000688F693 ---DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD -RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP -SAVRTMLARKGVSGVGFGPGERVLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR -HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS -TRQPIPVRMRLMGDVTRAIIR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Stigmatella aurantiaca TaxID=41 RepID=A0A1H7L6F0_STIAU ---------QRIAQVKGASVAVAYLNLGDSRDTvFLGAEASFHAASTMKVPVMIEFFRQVD -AGKLSLDQPVPLANRSIVDGSPYTYERLGQAVPASELLKRMVTRSSNLATNTLIARV-DA -KRVTRTLRALGARSMTVLRGVEDAK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ -AMRDILLAQEL-NTLIPAGLPPGTPVAHKTGQIT-GVLHDAAIVYPPGRAPYVLVVLTRD -IP-EAPVAEALIADLARQVHA-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8W4M3_9BACT --eKLEATINGVDRNLEGVLGVAILDLTTGQKY-FLHADEVLPTASSIKIAVLAELYRQAQ -QGKIKLGDLYTLQSSDLAGGSGIAGALTPGVLTIRDVAVLMISVSDNSATNIIIDRI-GI -ENVNALLDSLSLTQTRLRRKMMDVKAA-GEGRENIATPREMVTLLESLYRGRVLNKPMTE -DFFTLLSVHKE--SYIPRELPEDLRIANKPGELE-GVRNDSGIVFTGSR-PFAISVMTTY -LRRE-KDGGDAIVRIATAAYQMf ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WY31_9BACT ---SLAELISSIQVKSGGKVAVSVRHIETNQGG-SWRGFEEMPLYSVFKLPLAVVVLKDVE -AGKLQLDQRVSVKESDVAPIAANTDRNVPLEMTVRQLLELSLIESDNTSSDKLLQLTGGP -GALTKRIESLGFDKIKINVSVKEMSQN--KKHLNVATAESIVRLLSGLQQGSVLKDEQRT -VLFELMGKSRTGLKRLRGLLPAGTAVLDKTGTGPDGAINDVGIVTLPSGGHLAVAVLISG -SKLPVEEQEHMIAEIALASYKLf ->[subseq from] Beta-lactamase n=2 Tax=Clostridiales TaxID=186802 RepID=E7GH01_CLOSY --eNLKNRINEFIESQTGNICVSLFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVG -AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM -DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA -LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG -VK-TNKDGREAIGRISQIIYEE- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf9 TaxID=1735674 RepID=A0A0Q4CU02_9SPHN ---DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -QGRLSLADPVIVTRADLTLHQPIRTLVGKTGTTVGNLLRGAMSRSDNTANDVLLWRIGGP -AAVNRMLKDKGVAGVCFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPARMRLMGDVTRAVIA-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:462 TaxID=1262740 RepID=R7CZR4_9BACE ----LREEVGAFLRDKRATVGVSVL-TDSTTLL-AWNDTLHLPLLSVFKFPVALAVLHRME -QQQTPLDTVLHLTPDDLKTYSPLCIRYPERSIRMDSLLYYSVALSDNNACDVLLRYAGGP -RAVEQYIHQLGITDVRLSATEDDMHRQPGRVSDNSATPEAISRLFRLFLQEGLSAPVYRN -YLYRVLTSTSTGMNKLPAGLPDHAILGHKTGSSDKTADNDAGFVLLPDGQRYYITVLVTN -SLENDSVNAAIIATLSHIVCRH- ->[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139X861_9CYAN ---TLNSQIRALMERYSFLLGMFFLDLQTGDYL-NINGDKAFPAASTIKFPILIALFQEIE -AGRVRLDEPVVMRQDLVAGGSGMQSKSVGSRFTILQTATKMMTISDNTATNMIIDRLGGK -AVLNQRFHSWGLQNTTIRNLLADVNGT------NTTSAKDLVKLSALVTNNQLINDTSRS -QVLEMMRHCHN-QSMLPSGLGSGAIIAHKTGTLRF-VLGDAGIIQTPSGKIYLAGILVRR -PNHD-SRATEFIRRVSQFVYEY- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sporomusa termitida TaxID=2377 RepID=A0A517DYG6_9FIRM --eRLHTKIQTLLAQYSCRSAVIVRNESTGNAL-AINPAMVFPAASMIKIPIMIEVMRQAA -AGKLPLAKTVAITSQMQTGGAGILKEQPGIKMTVAELVTLMIILSDNTATNVLIDLA-GM -AAINAAITGLGLRSTVLQRKMMDFAAA-KAGRENLTSAADLARLFAGIAGSTAVPPPYNA -MMLDILKRQQI-RDKLPFYLPAEVIIAHKTGTLA-GAEHDGGILFAPGG-PYIICVLTAE -LTAN-YEGLQLVAMIGKIIYEY- ->[subseq from] serine hydrolase n=1 Tax=Runella zeae TaxID=94255 RepID=UPI0003FF81EF ----LRTSIVSKLGQIEGDFAVAFKDLQTQQTL-FINEKENFHAASTMKTPVMMEVFRQAQ -AGKFNLSDSILVKNESIVDGSPFKYKKIGSKMTIYDLTYQMMIVSSNLATNILIDLV-DA -KKANQFMRELGAKDINVLRGVEDTK-AFEKGLSNTTTAYDLMLIFEKIAQKKVVSPTASD -KMIQILLDQKF-NEIIPAQLPSNVRVAHKTGSIT-GVRHDSGIVYLPNGKAYVLVLLSKK -LTN-PEAGVKAMAEVSEMIYN-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Gammaproteobacteria TaxID=1236 RepID=A0A166NHH3_PSEAI ------------------------------------------------------------- ---------------------------------------------------DKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAA------- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A358AGR3_9BACT --dNLKKEIEGRIADFRGNIGIVIKDLNEGWEI-DFNKGALFPSASLVKVPILLSYFYAQQ -EGKVRTSDLVSLKSYEKVPGSKVLGDSSVGSFSVEELFEPMIAKSDNTATNILIDLL-GF -EAFNDYFIRLGLRNTNLVRRMMDFEER-KEGRENYTTAEDMAYLLEILYRRSFLDKNTSE -KCLGFLKQQKI-KDRIPRKLPEGVTVAHKTGLENY-ICHDAGIVFTQKGD-FLICVLTKH -QDKFAAPAKRFISDIALITYNYy ->[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=A0A1E4R8W0_9BACI ----LQESLEKVIQEATGTFGVYVKHLESGETA-AINENRLFQAASVFKIPILVTLYRDVQ -MGKVELKERIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLNML-GK -ENVNQYMKEIGLSNTYINLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDSGNFIISVFSIG -NI-TEAEGASIISKLSRVAYNHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI07_KLEPN --------------------GMIEMDLDSGRTLtAWCSDERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSENSATNLLLATVGGP -AGLTAFLRQIGENVTRLDRWETELNEALPGDSRDTTTPA--------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) TaxID=504472 RepID=D2QDV0_SPILD ---KLRQQIEQELSRHPGTFAVAFKDLKTGKEL-LIREHEVFHAASTMKTPVMIEVYKQAA -QHKLALSDSMTITTDSIVDGSSYSYKAVGTKRTLAALVYDMIIVSSNLATNMVIERV-GA -QNVTQTMRDLGAKDIQVRRGVEDSKA-FAQGLNNTTTAYDLMVIFEKIARGKAVSPDASK -AMITTLLDQKF-NDAIPGKLPKDVKVAHKTGSIT-GVRHDSGIVFLPDGRKYVLVLLSKE -IK-DDKETIETMATVSQWIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Euhalothece natronophila Z-M001 TaxID=522448 RepID=A0A5B8NR54_9CHRO ---DLKQTFERLGSEQQLNPTAFIIDVDSGEYV-DLQGNTTVSAASTIKLPILIAFFYAWE -QGELELDERLTMTEDVKVGEAGRMQDDVGTEYVALETATEMIRISDNTATNMIMKRVGGK -EVLNQLFAQWGLEKTRIRDQLPDVEGT------NTTSPKEMVELLVKLEKGELLSARSRD -KVFEILQTTET-DSLLPQGLGDGATIAHKTGHIGS-VVGDVGIINRPNGQRYFAAILVER -PHND-SHANELIRNYSQHTYQYf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc minutum NIES-26 TaxID=1844469 RepID=A0A367Q8R0_9NOSO ---QLSSQVKGLMARYSLEPGMFFLDLDTGNYL-DFNGEKAFPAASTIKFPVLVALFQEVD -AGRVKLNESLVMRRELMTGGSGVIQKRPGTRFSLLDTATKMITISDNTATNMIIDRLGGK -AKLNQRFRNWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLSALIVNNQVLSNSSRS -QVLSLMRRVEN-RSLLPSGLGKGAVIAHKTGTLGV-ILGDAGIIEMPSGKRYLAGIMVRR -PFND-LRGKAFISQVSRLVYSY- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides barnesiae TaxID=376804 RepID=UPI00037C980F ---SLRQELANRIKNCRAQVGVALV-VDGKDTL-TLFNEVPYPLMSVYKLHQAMAVGKYLH -ERGRTSESRIAIGKEDLKPYSPLRDKYPDGNLSVRELLEYTLQWSDNNACDILFAHTGGT -AGTDRYIRSLGLKEFAISSTEDEMHRDLDKCYDNWSSPLEMARLLEILFTTDLEMGEFQP -LIRQILMTCRTGLNRLPKPLENGAQIAHKTGTGDKNGINDAGMVFLPDGRRYTLVVFVKD -SWESMEKTEQLIADVSEIVYRY- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536FCW5_9CHLR ------RRIEEIGSGV-GIVGVAATRLSDGRHI-GIREDELFPTASVFKVPLLVALYAEAL -AGRLDLGERVGYRADTRVAGSGVLQFLDDGLPTLRDLAVLMMTVSDNTATDLVLERV-TK -DRVNATMREYGLRSIAVPFGTREMLMSIVPAETDRTTPREMCRLLELLATDAILDAGSCR -AILEIMERIQS-GTRLPGLLPKGTVVAHKTGSLRR-TRNDVGIVRAPNGA-YAVAIFTRE -LVRDNVDDERAIAAMSLAVYE-- ->[subseq from] serine hydrolase n=1 Tax=Planococcus sp. CAU13 TaxID=1541197 RepID=UPI00053001D1 ---QLQQQIEQYISGIDAEFGISIKHLKTQEEV-NIQGDRLFQMASVVKVPILATLYDLAE -KGEIDLNQRIEMLDEDHVPGSGVFKAMDSGIPTIKDLATMMIIVSDNQATDKLLELVGGA -EAVEEKMKSIGLNNIHIKHSIWDLLSFQESPESNTSTAKDMTLLMEKIAMGEFVSKECSA -AIYEILLKQHY-QQRIGGSLPRNTKVANKTGSLGT-MFNDTGIVQLPDKGAFVITVYSIG -SSLD-YKGDEPIAEISRMAYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A3B9ZHF9_9BACT --qALERALSQEVSRFQGEAGVILKDLDMDWQI-AVNKTKSFPSASLAKIPIMASCFYAVF -QGKIKLQDELILKERHKVLGSGTLKTMAAGRVSIENLIERMITESDNTATNMLIELL-GY -EYMNSCFKEFGLKDTSLARKMMEFKLR-RKGVENYTTAGDVALLLEKMYRKEVINAEFSE -RCLSLLKQQKI-KDRIPALLPPEVVIAHKTGLERH-VCHDAGIVFSPGGN-FLLCVLTSH -TDKTSKRAKEFIARLAFEAYRYf ->[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522P938_9BACT ---QLQSHLDSLARHAPGDVAVAVRDLRTGEVV-GYNAHASLPAASTIKVPVMVEVFRQME -AGAFTLDRDVTLASADRDGWGDLADAPAGSHYTVRRLLWLMITQSDNTAANMLIRLV-GR -AHVNQTMHALGLGNTSLSDYIRSYGDI----RSIRTTASDMVRLMAMIAHGTLVDEWSCG -EMLEIMAGQQI-NTLLPQPLPADVLVAHKTGSLHD-TLNDVGVVYLA-GAPYAIAVMTTH -LA-SLDSGRAFIHAVSSLTFK-- ->[subseq from] Serine hydrolase n=1 Tax=Parabacteroides distasonis TaxID=823 RepID=A0A3L7ZL56_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRIGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9G4_SHIFL ------------------------------------------------------------- -------------------------QKSIGRMASQEEDCSADITMSDNTAANLVLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLNSALPAGWFIADKSGAGERGWRGINAALGPDGMPSRIVVIYTTG -KQATMDERNRQIPEIGASL---- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ZX TaxID=2606412 RepID=A0A5D9C947_9SPHN ---ALDRRIEALGSGFRGDVGLAVRDIQTGWIS-HYRGLDYFPQQSVSKLWVAISAFDMAD -RGKLDLRGRLSVRPNDLTLHQPIRSLATRPGTDREDLLTRALTQSDNSANDKMLREVGGP -DAVRATLAAKSISGIRFGPGEKGLQSAYVADPVDGARPIAMVDALARLKTGELLSDASTA -QMLDLMGQTRTGALRLKSGLRPGWTLSHKTGTGQQAGYNDVGILTSPEGRSYAVAVMIGR -TSRPLPERMDLMRKVVRLTIA-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus telephonicus TaxID=1714840 RepID=A0A3S0QXT4_9BACI -----KEKVQRLIEEVRFDVKVVVSEANSNEFLiGIGIDDVFQSASLIKVPIMLAVLDYVE -DNNVSLKQVIAIKEENVVDFSMITEQGLK-NSTIYDLLVGMIITSDNTATNVLIDFI-GM -DNLNQYFKKIGLTQTILNRKMMDFEQV-KKGLDNVTTARDMSVLFRHIYRQDLLTPKNCE -LALNILKRQRI-YESLKRYLVDDVTIAHKTGSLDT-VEHDVGIVFSPLKD-YMIGIFVTN -HC-DNEEAKRLIGRISKVVYQHf ->[subseq from] Serine hydrolase n=3 Tax=Nostocaceae TaxID=1162 RepID=A0A1W5CH86_9NOST ---QLDSQIKQLMNRYSLSAGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFEEID -AGRINPNETLVMRRDLMTGGSGTMQYRKAGSFKLMETASKMMIISDNTATNMIIDRLGGK -NRLNQRFRSWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALISNNKLLSATSNS -RVMDIMSRCKN-RSLLPVGLGKGAVIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGIMVAR -PFGD-ARAKAFINQVSRLVYG-- ->[subseq from] Class A beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A4V6RE54_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI0009EB1A4D ---DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDTPRPQQSVSKLWVAIGVMDAVD -QGRLSLADPVIVTRADLTLHQPIRTLVGKTGTTVGNLLRGAMSRSDNTANDVLLWRIGGP -AAVNRMLKDKGVAGVCFGPGERQLQARYLDAPLDGASANGVTLGLSLLAQGRLLSDRSTA -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPARMRLMGDVTRAVIA-- ->[subseq from] Beta-lactamase n=2 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RCA7_9BACT ---RMEDSVRAIAERTDAVVGVAILDLTDGRAL-YLNADAAYPTASTIKIALLAELYRQDE -RDGAKLGDTYTVDAKDAVGGAGIMGGLSPGALTNRDLARLMVSLSDNSATNVLIDRV-GM -ERVNALLSGLGLEKTRLRRHMMDTRAA-REGRENTATPRELVTLLGALHAGRVLGRVATD -SFFAMLSTGKN--GYITRLLPPDVTVANKPGDLD-GVRNDAAVVFVPGR-PFAIAVLTTY -GG-DDRAAEGRIAEIARAAWTYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A8_9BACT -------------------------------------------------VMAVSALLKQSE -TDKNLLAKRMEIKQSDLVNYNPIAEKHLDTGMTLGEFSAATIQYSDNTAMNKILEHLGGP -AKVTEFARTIGDKTFRLDRTEPTLNTAIPGDKRDTTSPLAMAKSLQNLTLGKALGEPQRA -QLVEWMKGNTTGGASIRAGLPTT------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=unclassified Lysinibacillus TaxID=2636778 RepID=UPI000B7C64A2 ----LQESLEKIIQEATGTFGVYVKHLESRETA-AINENRLFQAASVFKIPILATLYRDVQ -MGKVELKEHIRLEEEDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLSIL-GK -ENVNQYMKEIGLSNTYIRLSCWELLCFKESHANNVTTAADMALLLEKMANKQLISEKACH -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGNFIISVFSIG -NN-TEAEGASIISKLSRVAYNHf ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum CTI-5 TaxID=1316586 RepID=U7T4W2_FUSNU --tEWKKEIEKIISRVKGSVCINFYDLAKNNGF-SINGDKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKKASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIENKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Pseudonocardia acaciae TaxID=551276 RepID=UPI0009FFDE6B ------DELAARATKLGGALGAVIEDLRTGRRA-EVGAQRAFTSASVIKLPIAMTVLA--- --GELPLDRQVMVRAAARAGGSGILRDLEVPALSVRDLLTLMITISDNTATNVLIDLV-GI -DAVNAWCAGHGLTGTVLARRMFDAEAR-ARGEENLTTARDVATLLADLARGRLLDPPATD -FALDVLARQRV-NDRLPRHLPDGLRLAHKTGELD-GIRHDAGIVLDKGK-PTIVVVALTE -AINSAATACDLIAEVGRLAY--- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI001447BAC8 ---ELQTPIKTLMARYKLSPGIFFMDLETGDYL-SINGDKSFAAASTIKYPILIALFQQVD -AGEIQLDETLVMGRKHIVGGSGNMQYKVGSKFSLLETATRMMTISDNTATNMIIDRLGGI -TQLNQKFRSWGLENTVMRNRLGDFNGT------NKTSAKDLVKLSALMENNQLVSNTSEL -QVIGIMNGCHN-KSLLTSGLGSGAKIAHKTGTLRF-VLGDAGIIETSSGKRYLAGVFVQR -PNND-SRGTDFIRQVSQVVYGYf ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=Enterobacteriaceae TaxID=543 RepID=A0A125SIY0_ECOLX ----------------------------------------------------CGAMLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDR-------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D4Y5D5_9SPHN ----LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD -EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKSCNDCTDALLNAVGGP -SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR -VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Atelocyanobacterium thalassa isolate SIO64986 TaxID=1527444 RepID=A0A086CHW6_9CHRO -----KKQLEDINIKYDVQPKAWFFDLDTNTYV-NFNGTKSISAASTIKIPVLIAFFEKVD -AGDISLDQMITMDKEMIVSGSGNMQYMQAGKFTALEIARKMIIISDNTATELLVRQIGGK -FFLNERFKKWGMKQTVINNPLPDLNGT------NRTSPEDLTKLLLRIERGDLISLRSRD -RFLNIMRETKT-KTLLPKGLEKNASIAHKTGDIGT-IIADAGIIDMPTGKRYIGSIFVER -SY-DDPAGRELIQKFSKAIYQY- ->[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:1185 TaxID=1262921 RepID=R5MI05_9BACT ------KAVESLIKGKDAEIGVAWME--GNAMY-SVNNERLYPLMSVCKLHVAIALLRGME -RRGAAVDTTLNITPEQMRKYSPLLKLHPDGRITLRQLIHYAIAESDNNAADILTAMAGGI -DSVDREIHAMDIKGCHLAETEASMHDAPINSYANWSKPESVVWLLRKLYDGRLLSGEYDR -CIKQALAATTTGADRIKAGLGQGMTLAHKTGTGFKTADNDAGVVTTSDGRQVIMAIMIKD -SKMSDADNARLMAEITRIIM--- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacterium thermosaccharolyticum M0795 TaxID=698948 RepID=L0IPB7_THETR ----LYDDIKRFVTSTDGNIGVSIKNLKTGERI-DVNEEMMFPSASTIKILIMAQIYKMAK -EGYIRLTDNIVLSDFMKTAGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINRMAEDLGMLHTKIQRKMMDFEAA-ESGKDNYTCAKDMTHLLELIYAGKVVDKEYSN -MMLNILKKQQD-LGRLDLYLPEDVLIAHKPGELKL-LEHDVGIVFLKNCQ-YIISVMTNN -LSTN-LDGRKAIGKISKMVYDEy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas astaxanthinifaciens TaxID=407019 RepID=UPI0004A733EA ------------------------------------------------------------- ---------------------------------SARGLLEAMLIHSNNVATDHLINNLGGP -TAVQSWLTFNNVRGVRVDRTIARLLADKRWDLRDSATPLAMVQLLRTIDRGNVLSQSSHR -YLLSVMARCQTGKNRIRGMLS-GVPIEHKTGTLNN-YASDVGFITMPDGRRLAIAIFARG -GT----DRPTTIAQTARTIYDGf ->[subseq from] serine hydrolase n=1 Tax=Spirulina major TaxID=270636 RepID=UPI0009355AFF -------TLDAIAAQQDLQTSVFVVDLDTGDFV-NLNGTATMAAASTIKLPILIAVFQEVD -RGLVDLSEPLVMTTEMMASGSGTMQYTPGTTYSLEATAEKMITISDNTATNMLIQRLGSA -PLLNERFRDWGLKQTSIQNLLPDLTGT------NETSPLDLVTLLAMVHDGKLVSLRSRD -QLIRIMQQVEN-RDLLPQGLDEQAVIAHKTGDIGS-MLGDVGIVDTPMGKRYAIAALVGR -PHND-DRARILIQDLSRATYQHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V590_9BACT -------------------------------------------------FMVASAILKESE -VKKNLFTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Thermoanaerobacterium sp. PSU-2 TaxID=1930849 RepID=A0A1X2FWX4_9FIRM ---SLHDDIMNFVSNAGGDIGVSVKNLKTGEMI-GVNEEMMFPSASTIKILIMAQIYKMAK -EGYIRLTDNIVLSDFMKTDGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGLFHTKIQRKMMDFE-AIKSGKDNYTCPKDMTRLLEQMYSGKVVDEEYSI -KMIEILKKQQE-FGRLDLYLPDDVLIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN -MNTN-LDGRMAIGKISKMVYDEy ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI000A03EE7A -----VNRLSDIARNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudanabaena sp. TaxID=1153 RepID=A0A352JFG1_9CYAN ------NKIKELAKEKDLSMQMMMVDLDSGVYV-QIGANQPITAASTIKTPVLVAFFQDVD -AGKIKLDEPLEITSDVKVGEAGDFQFLPGTKISAITTATQMIVISDNTATNMIIKRLGGF -TALNQRFKSWGLSNVVINNPLPDLEGT------NTISTQDMVTLLAMIDKGKLIEPRSRD -RFMDIMRRPIT-NTLLPKGIDEEARIVHKTGDIRS-AVGDAGIVDMPNGKRYAIAVMVKR -PDND-QRANELIRQISRATYDYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI001430FF3A -----VNRLSDIARNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=A0A2P4UNU4_9ACTN ---KALDELAHRAEGRGGVLGVVVQS-ANGEYA-SVNADRAFTAASLIKLPVMLALLDGVE -AGRWSLDDRLPVR--DRVGGAGILRDLADVALSVRDLVTLMIVISDNTAANLLIDRI-GA -PAVADWCGRHGLRATVLERRMMDAEAR-ARGAENRTSPADMAKLLDGLVRGTLLGPAMTA -FALDVLARQQV-RDRLPRYLPAGLRIAHKTGELD-GLRHDVGIIFTN--APIIVAALTEN -AD----EADDLIAESARRAVQ-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A3N2K5X7_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFEGAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=A0A126RVL4_9SPHN ---DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD -RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP -SAIRTMLARKGVSGVGFGPGERLLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR -HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS -TRQPIPVRMRLMGDVTRAIIR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A3_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALRKSDRVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Paucisalibacillus sp. EB02 TaxID=1347087 RepID=UPI0012DE4269 --rELSERISQITEDASGTWGISLHDLDTDEKW-ELNAHELFYSASVIKIPIMITVFASSH -RNQFSLSNCLTLKREDLVGGSGVLQHMTPGTISIYDLIMLMIIQSDNTATNMLIDLV-GT -EAIQQTMKNIGLEKSNFYHKMMTIDV--EREGLNEITAHDMTNMLKKILTGKIISAHACE -QMIDILKKQQV-RNSLPAKVPKQWEIANKTGNVS-GIRHDVGIFYVGKR-TFIASVLTRG -LD--DLQSPEIIGRVGLEIYQY- ->[subseq from] Beta-lactamase class A n=2 Tax=Bacillus simplex TaxID=1478 RepID=A0A1N7GKE6_9BACI ----LQDRLEEVIQDATGTFGVYVKHLESGETA-AINENRFFQAASVFKIPILAALYRDVE -IGKVRLQERIRLEEVDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLNIL-GK -ENVNQFMKEVGLNNTYIRFSCWELLCFKESIANNVTTASDMALLLERIAYKQLISEKACD -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGRFIITAFSIG -NK-TEAEGAGIISELARVAYNHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9QD60_9BACT --dKLESQIREIDRNLDGVMGVAIEDLTTGQKF-FLHEDEVFPQASSIKIAVLAELYHQAQ -SGKARLADLYTVEAKDMVQDSDIMLGLTPGVVTNRDLATMMVAVSDNSATNVLIDRL-GM -ENVNALLDSLGLTHTHLRRKMMDVKAA-SEGRENVSTPREMMTLLEQVYRGKILNKEMTD -DFLKMLATHKG--SAISRDLPEGVRSADKPGELE-GVRTDSGIVFAENR-PYVISVMTTY -LHN-EHDGAEAIARISVAAYGMf ->[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI001196401A ---ELQDRLEEVILDATGTFGVYVKHLESGETA-AINENRFFQAASVFKIPILAALYRDVE -IGKVRLQERIRLEEVDLVNGSGIFKELIPGIVTIKNLATMMIIVSDNVGTDKLLNIV-GK -ENVNQFMKEVGLNNTYIRFSCWELLCFKESIANNVTTASDMALLLERIANKQLISEKACD -DMFEILAKQQF-RSRIPYLLPQNTVVAHKTGTIAS-VVNDSGIVQLPDNGRFIITAFSIG -NK-TEAEGAGIISELARVAYNHf ->[subseq from] Serine hydrolase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=A0A1P8JQ59_9BURK ---RMQAEFTRIETQSGAGLGVYVRDLGTGHAA-SHRAEETWYLASTVKVPIAIAVLRGVD -RGDYRLDTRLVLRDTDLVDGAGQTKQHVGAPLSIRYLLNQMIVYSDNTASDMLIGLV-GI -DAVNAVVHELVPQGFQRITTLADVRRAYYATGLNSGRLDAYADLLELLARGKALSAGSTK -YLLGVMERVRTGPNRIKAGLPPRAHFAHKTGTQR-ARTCDSGVVTLPGRDQRVVVVACTS -GELSSTRSDHTLRQVGTALCK-- ->[subseq from] serine hydrolase n=1 Tax=Gudongella oleilytica TaxID=1582259 RepID=UPI000FF8972A --------VMEMMKELKGNIGVYYKDLTTGESF-GIRADEKYLAASVIKLMVLLEAFKQES -QGKISFDQFIEIKEKDKLPCGSLTYMHDGLKVTIMDLCVLMIIQSDNTATNIMIKLL-GM -DSINSTIRELGFEKTKLNRLLFDSEEQ-KKGKENYISPLEMGTFLEKLYNGELISKKASM -AMLDIMKTQQL-NHKIPYYIPKGVKIAHKTGEDD-GITNDVALVFSE--RPFIICFAAYG -TNVQ--MTEDFYRKAAKLFYD-- ->[subseq from] Beta-lactamase n=2 Tax=Fibrisoma limi TaxID=663275 RepID=I2GJ30_9BACT ---SLTDSLTAYLRRLNAQVSVAVESLADSTRSfHHQADERVPSASLIKLPILIEAMERIK -AGQLDPDEIHILTDSEKTGGDGILKTYSHRSIAYRDIIRLMMIHSDNTATNILINEL-GM -NAINQRIRSLGLAKTQLNRVMMDTAA-VRQGRENYVTAREMNQLLTKIYQHQIATPALCD -QMLDILKQNEN-RQTIPRLLPNTVVVAHKTGILSY-VRGDVGIIYAP--QPFVLSVLVQG -VS--TAEAERIISEIALMCYNHy ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium chungbukense TaxID=56193 RepID=A0A0M3AKP9_9SPHN ---DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD -RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP -SAIRTMLARKGVSGVGFGPGERLLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR -HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS -TRQPIPVRMRLMGDVTRAIIR-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. TKS TaxID=1315974 RepID=UPI0009EB055D ---DLLNAVQGLGSAYKGKVGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD -RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP -SAIRTMLARKGVSGVGFGPGERLLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR -HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS -TRQPIPVRMRLMGDVTRAIIR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=A0A4Q7SGS5_9SPHN ---DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTQSDLTVHQPIRALVGKDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -AAINRMLATKGVAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSPRSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPARMRLMGDLTRAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Ignavibacteriales bacterium CG07_land_8_20_14_0_80_59_12 TaxID=1974045 RepID=A0A2M6YY62_9BACT --dKLLAHLQSIVDTSDAVVGIAAKDLTSGEEF-FINENEIYPQASAIKIHILAELYRQAA -EKKFSLSEIRPLPESERVGGSGVLNELGRNTMSIRDYAVLMIVLSDNTATNVLIDLV-GM -DNVNKFLGGLGAQKTRLQRKMMDYKAA-AEGRENIGTPKEVLMVLEKMYLGEISGRAASE -DMLSIMRKPKPG--PIRSGVPATVDVANKEGEIE-GIRTDVAIVYLPGK-PYAICVMAKY -LLHD-EDGPRIITDVSSAVYSYf ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009903361 ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Calothrix sp. HK-06 TaxID=1137096 RepID=A0A1Q4S0B8_9CYAN ----LETQIKTLMNRYSLTPGIFFLDSQTGDYL-NINGEKIFPAASTIKYPVLIALFEEVD -AGRIRLNETMVMQRRHLAGGSGNMRFRPAGTFSLLETATRMMTISDNTATNMVIERLGGI -AKLNKRFRTWGLEQTAMRNMLGDFGGT------NRTSAKDLVRLSALVTNSNLLSDASRN -QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTASGRKYLAGILVRR -PHHS-PQARDFIRQVSQLVYNH- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLE TaxID=1985878 RepID=A0A430EPD8_9SPHN -----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAVVAE- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. ABOLD TaxID=1985877 RepID=UPI000F7E4447 -----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAVVAE- ->[subseq from] Beta-lactamase class A n=1 Tax=Rivularia sp. PCC 7116 TaxID=373994 RepID=K9RI85_9CYAN ---QLHSQVKSLMSRYSLDPGIFFMDLETGDYL-DINGEKAFPAASTIKLPLLVALFEEVD -AGRVKLNETVVMRRDLMTGGSGTMRKRPGTKFSLLETVTKMITISDNTATNMVIDRLGGK -ARLNQRFRNWGLQNTVIRNLLGDFKGT------NTTSPKDLARVGALISNNLLLSNSSRA -KVLDIMHRVEN-KAYLASGFGRNAKFAHKTGTLGI-VLGDAGIVTMPNGKRYLAGIMVNR -PFRD-RRAKSFIKQVSRMVYGH- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus parviboronicapiens TaxID=436516 RepID=UPI0006D109FD -----EQMLRQLLQKSPYKMHMIVKDLSTDEIIiSERYDDVFSSASLIKVPILLAVLHHVQ -TNKVALHQVLTISPKDWVDFSGISEQQLQA-ASIYELLVWMIITSDNTATNVLIDFM-GM -NVLNRYFREIGLTHTILQRKMMDFER-LANGVDNVTTARDMTHIFTHMYHQDLLMPSYSA -LAIDILSRQRV-HESLRRYLIDDVTIAHKTGGLET-VDHDVGIVYSDAK-DYLIGVFITE -VTNN-QDARQLIGRISKVVYEY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI000EAEACA5 -----VNRLSDLAQNFNGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIHLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. ABOLE TaxID=1985878 RepID=UPI0013E038DC -----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAVVAE- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas TaxID=13687 RepID=UPI0013DEBAC3 -----VNRLSDIAHDFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAVVAE- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0037 TaxID=2133752 RepID=A0A544UTL3_9BACI -----KQTITQILQKAPYKVHMFVKDCKTEHFFiSEKLEDPFSSASLIKVPILLAVLNYIE -SNNLSLEQEIKIAPEEWVDFSVISEQRLEQ-STIYELLVWMIITSDNTATNILIDFL-GM -DTLNQYFRQIGLLQTTIQRKMMDFER-LAKGFDNTTTAKDMALLFSRIYRRDLLSSASSE -VTIGILSRQRV-HESLKRYLVDDVKFAHKTGGLNT-VDHDVGIVYNSSGD-YLIGVFVTE -VTN-NDHARQLIGRISKVVYDY- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A543LTQ3_9SPHN -----VNRLSDLAQNFNGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIHLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. AG:487_50_53 TaxID=1897014 RepID=A0A1Q6HM45_9BACT ---SLAERIDSILSGRRMTVGVSAEC-GDFSYV--RNARVRFPLMSVFKVHVAMKVLADMS -ASGTSLDTVVHVERAMLREYSPLRDARPSGDITLAGLMRYSVAESDNNACDILIRMAGGI -GQVDRYVRSLGVDGFRLMHNEDAMHRDITRCYDNWSTPEAMTRLMKIVFEGSA---PLYA -PLRSMMAATVTGADKIRAGVPESLPVAHKTGSSDKTGDNDVAVVRMPSGRNCYITVFIKD -SAETDAVNAAVIAAVAREIVE-- ->[subseq from] serine hydrolase n=1 Tax=Microcoleus sp. IPPAS B-353 TaxID=1334624 RepID=UPI001357D54E ---DLTGQLQGLVAEYELTPGLMVVDVTTGDYA-QMGQDRPFAAASTIKIPILVAFLQAVD -AGQVRLDERLRLEESHIAGGAGRLQDEVPGSFSALEVATLMMVQSDNTATNLIIDRLGGL -ATLSSQFREWGMQETVLEDWLPDLQGT------NQTTPRELAGLLAQIERGELLSMASRD -RMLRIMMLTQN-NGLLPQGVGEGGVIAHKTGNLRF-VLADAGLVDVVNGRRYVLVALVER -PEY-EEEAADFIRELSARVYGYf ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00073BF40F -------------KASCGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEA--------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Class A beta-lactamase n=1 Tax=Parabacteroides distasonis TaxID=823 RepID=A0A1Y4IR27_9BACT --kTIEKALLEYVSDKDARIGIAVI-VNGTDTV-SVNGKRDFPMMSVVKFPLALTVVQWID -ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTIRELLEWSLVESDNNAADILLNHVGGI -SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAELFDRFDNEMRNTSLSYS -EIATMLEQCRTGIDRLVAFLSSDATIGHKTGTGFISAINDCGYVNLPNGARYSIAVFVAD -SGYDMAETSAIIAEISRIVW--- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Enterobacteriaceae TaxID=543 RepID=A0A2P1JHI0_ECOLX ------EQIKLSESQLSGRVGMIEMDLASGRTLtAWRADERFPMMSTFKVVLCGAVLARVD -AGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETXLN----------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A2E0Q6F1_9SPHN ----LDDQLFALGTGLDGKVGIAVYDPARGRMV-HFKGTRLYPQQSVSKLWVALTALDMAD -RGQLGLGETGTVRMGDLAVHSPIRQNVIAQGSTYADFIKRALTQSDNTANDTVLRRVGGP -EQVRKTLAKKGFADIRFGPGERPMQSAYVDDPVDGATPVAIAAALAQLKQGELLSPANTA -QFLGWLGEVKSGPNRLKGGLPEGWSIAHKTGTGQQAGYNDVGILTAPDGSIYTVAVMIGR -THVSIPERMEMMHGVVRAIAG-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas pokkalii TaxID=2175090 RepID=A0A2U0SJ89_9SPHN ---ALLNAVQALGAGFQGQVAISVRDIDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HQRLSLATPVTVTRADLTVHQPIRPLIGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQNRLLDRASTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVIR-- ->[subseq from] CblA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SJC4_9BACT ----------------------------------------------------ALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMIDTETGANKLKGMLPAKTVVGHKTGSSDRNADNDAGLVILPDGRKYYIAAFVMD -SYETDEDNADIIARISRMVYDA- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=J9V7B1_ECOLX -------------RQSGGRLGGALINTADNSQI-LYRADERFAECSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQ----------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=UPI0009F841BE ---RMQAEFTRIETQSGAGLGVYVRDLGTGHAA-SHRAEETWYLASTVKVPIAIAVLRGVD -RGDYRLDTRLVLRDTDLVDGAGQTKQHVGAPLSIRYLLNQMIVYSDNTASDMLIGLV-GI -DAVNAVVHELVPQGFQRITTLADVRRAYYATGLNSGRLDAYADLLELLARGKALSAGSTK -YLLGVMERVRTGPNRIKAGLPPRAHFAHKTGTQR-ARTCDSGVVTLPGRDQRVVVVACTS -GELSSTRSDHTLRQVGTALCK-- ->[subseq from] Beta-lactamase n=1 Tax=Koribacter versatilis (strain Ellin345) TaxID=204669 RepID=Q1IIZ9_KORVE --qKMTADVTAVQQHFDGVMGITIRDLTDNREF-TLNPDDIFPTASSIKLPLLVELWRQSQ -TGTQKLTDLYTFRKEDVVPDSAIMENLTPGVVTNRDLAGMVVAVSDNSATNVLIDRV-GF -DNVNKMLDAQGLHKTRLRRHMMDLAAA-KAGNENVSTPHEMTQLLEAVYRGKILNPQMSE -DFWNLMCTKKE--SPLPRLLPEDLRIANKPGELD-GVRTDSGLVFLKNR-PYVISVMTTY -AA-NEREASAAIAQISLIAYNYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rahnella aquatilis TaxID=34038 RepID=U6A6G8_RAHAQ --------------------------------------------------MAASAILKESE -VKKDLLTQHVELKKSDLVNYNPITEKHLNDGMTMGELAAAALQYSDNAAMNKLIEHLGGP -QKVTDYARTLGDKTFRLDRTEPTLNTAIPGDDRDTSTPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPVTWVVGD-------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=3 Tax=Calothrix TaxID=1186 RepID=A0A2H2XXG1_9CYAN ---ALETQINTLMNRYKLSPGIFFLDLQTGDYL-NINAEKIFPAASTIKYPVLVALFEEVD -AGRVQLNETMVMQRRHLAGGSGNMRFRSTGTFSLLETATRMMTISDNTATNMVIERLGGI -AKLNQRFRAWGLEQTAMRNMLGDFGGT------NKTSAKDLVRLSALVTNSQLLSDASRT -QVLNIMYRCQN-RRLLPSGLGKGANIAHKTGTLRF-VLGDAGIIQTASGRRYLAGILVRR -PHHS-PQARDFIRQVSQLVYTH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Citrobacter freundii TaxID=546 RepID=A0A1D8MAM1_CITFR -------------------------------------------MMSTFKVLLCGAVLSRID -AGQEQLGRRILYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPYDERDT-MPVAMATTLRKLLTGELLTLASRQ -Q----------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000D72A331 ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0AUR4_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -ARVQAFTRSAELKAADLQDTMRDAYARYYQRGLNTATMEGYGAMLEKLVQGKLLPDAKRD -MLFEYMKINEPGEYRLAGGLPRKTSFIHKTGTQFE-RACHVGVINPRESAAIVVAACVEG -VDEN-KPAENLLREVGQAVAQ-- ->[subseq from] serine hydrolase n=1 Tax=Alkaliphilus sp. LacV TaxID=1482732 RepID=UPI00125D3641 -------------QGVEANVSIVLNDLTRDKWVlRYKENKKFPSASTIKILIMVEALKQVN -EGKFTLEQKITAKDSDRVEFSIISELNIS-EYTFKDLIILMIIISDNTATNMLIDMV-GY -ESINKMAGVLGLSSTVLKRKMMDFEAA-KAGRQNETSAIDMAKILQKIYNKSILNEEMCE -IMIDILKRQKH-KDSLSRYITDEVTIAHKTGELDR-LNHDIGIFYLEDI-HYILGVFVTD -AQ-DNLEAKRIIGSISKLVYEHf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter litoralis (strain HTCC2594) TaxID=314225 RepID=Q2N5T1_ERYLH ----FEQRVAQLADGTDGRIGVYALDLSTGREI-GVLADQPFPMASTSKVAIAAVYLAGVD -AGKWSLSSEWRLPR-------------PGGKVPAKTLLDLMVSKSCNDCTDALLSAVGGP -EAVNRWMRQAGISGFQLNRTIRTLINASQIDHRDAATPRAMGQFLAGIHQGRWLSASSRR -VLLDAMLGTTTGDRRMRSALPMSANLAHKTGTLSR-TASDIGLFRTSDGRIIAAAIYVTG -QSSSMSAEN-------------- ->[subseq from] class A beta-lactamase n=1 Tax=Odoribacter sp. Z80 TaxID=2304575 RepID=UPI00137AC775 --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMFLNDTVTFSEKAMKEYSPMLKKYGKSRMTIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Serine hydrolase n=2 Tax=Caloramator sp. E03 TaxID=2576307 RepID=A0A5B7TJW3_9CLOT ---------KSQMNEYDIKYSLSVKRLDTGQEF-NINENEVVPSASTIKVFIMAEAIRQMK -EG-IVKNERIKVSTKDYVPYSIISLLNPENTYTMMDLITLMIIQSDNTATNVLIDIL-GM -DKINAFIKSIECNSTILERKMMDLDVR-KRGLENKTTSKDLTHFMELLYKGRIVDEKSSK -TMIDIMKHQLD-SSMMRYFIPEEIEVANKTGELD-GIDNDTGIVYLNKGD-YIFTMMTRD -AK-SNNEARFAIAQVSKIVYEYf ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter jejuensis TaxID=795812 RepID=UPI0013697D7E ----LDDAVFTTANVFEGYVGIAIRDIERGRVI-HFNGERMFPQQSLSKLWVALAALEKVD -EGELDLAEKVSIRRSDLTVHQPVRKIVLARGTDYGDLLRRAITESDNTANDMLLRRVGGP -PGVRNAIAAGDLGAIKFGPGERAMQSGYVNDPVDGASPNAIAAALARLAQGDLLEPPTTD -LFLRLLDAVKSGPNRLKGGVPEGWSIGHKTGTGQQAGYNDVGILTAPDGHRYAVVVMIGR -TATPVPERMELMHRIVAATVAY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6DGR6_9BACT --kKLELRIDEIAMRFDGVMGIAIVDLTDGRPAlLRNAEHVFPAASSIKLPILLELYHQDE -KGKATLDDLYTVDPKDLVEDSRVMGGLSAGVVTNRDLAQFMVAVSDNTAANVLIDRI-GK -DNVNATLRGLGLTKTMLRRKMMDVTAAQ-RGDENVATPHEMVQLLEAIYKGKVLKADSTK -QLIKQLSTLKP--SYIPRDLPDGVQVANKPGELE-GVRTDSGIVFSANR-PFAISVMTAY -AS-DERAAERAISDVAREAYHYf ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WY39_9BACT ---ELRQQIEQELARHPGVFAVAFKDLTTGQEL-LIREKELFHAASTMKTPVMIEVYKQQA -QHKLSLSDSILVKNESIVDGSPFSYKQLGTKRTLASLVYDMITVSSNLATNLIIEKI-DA -RKVTQTMRELGANDIQIWRGVEDSKA-FAKGMNNATTAYDLMVIYNKLAQGKVVSPEASK -AMIGVLLEQKF-NESIPAKLPKEVKVAHKTGSIT-GVRHDSGIVYLPDGRKYVLVILSKQ -IKDD-IETQNAMATISEWLYHY- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium sp. oral taxon 203 TaxID=671211 RepID=A0A223AZM1_9FUSO --tEWKKEIEKIISQVDGKVCINFYDLDKKNSF-SINGNEKVLSASMIKLLILAELMKKVS -ENKFSLSDTITITNFMKTRGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKETFLERRMMDAEA-RKNGYDNYTCADDISSLLKLIYQEKLINKEASQ -FMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDK-VYILVVLTSG -MS--NLECKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E4CVF7_9SPHN ------------------------------------------------------------- -------------------------------GISGREHLDLMITRSCNDCTDALLKAVGGP -RAVNAWMRQAGIYDFELTRDIATLVRASQIAFEDSATPRAMGQLLAGIYQGKWLSAYSRQ -VLMNAMSGTVTGKRRMTSALPDSANLAHKTGTLSR-TASDIGIFFTPDGRPIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=A0A2N6TJD3_FUSNU --tEWKKEIEKIISRVKGSVCINFYDLAKNNGF-SINGDKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQKKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG -MP--NFQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=UPI0013EEBEBF ---DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTQSDLTVHQPIRALVGKDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -AAINRMLATKGVAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSPRSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPARMRLMGDLTRAVVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V570_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLSTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Calothrix elsteri CCALA 953 TaxID=987040 RepID=A0A2A2TQL0_9CYAN ----LKTQVQTLMAKNKLAPGMFFLDLESGDYL-DINGDKVFPAASTIKYPVLIALFEQVD -AGKIKLDETLVLRSSQKAAGSGTLQYQASGILSVAETVNKMISISDNTATNMIIDRLGGK -EKLNQRFQNWGLQSTVIRNRLGDFKGT------NTTSAKDLVRLSALIENHKLISDTSHL -QVIEIMRNCHN-AKLLAAGVGKGGKIAHKTGDIGF-VVGDAGIIEMPNGHRYLAGFFVRR -PH-DDERGREFVRRVSRMVYEHf ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3NZC0_9FUSO --tEWKKEIEKIISEVKGQVSVSFYDLDKSTSF-SIDGDKKVLSASMIKLLILAELMRQVS -EAKLSLSQKITLTDSMRVGGDGILKVLDSGHFSLKELAKLMIVVSDNEATNILIDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLRLIYEGKLINEEASE -IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTGA -MP--NLECRETIGKISKYIYN-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Calothrix TaxID=2619626 RepID=A0A2H2Y4T3_9CYAN ---ELQTLIKSLMAKYRLTPGIFFMDLQTGDYI-DINGAKAFSAASTIKYPILIALFQEID -AGRVKLDETLVMRRTVMVGGSGNMQEHAGKKYSLLETATQMMTVSDNTATNMIIDRLGGI -AKLNQKFRSWGLQSTIMRNRLGDFSGT------NKTSAKDLVRLSALMASNQLLSEASQS -QVTQIMYGCHN-RTLLPSGLGSGAKIAHKTGTLRF-VLGDAGIIETLSGKRYLAGIFVHR -PDND-NRARDFIRQVSQVVYGYf ->[subseq from] serine hydrolase n=1 Tax=Hassallia byssoidea TaxID=482630 RepID=UPI000585BD16 ----LNSQIKALMNRYSLNPGMFFLDLQTGNYV-DINGEKIFSAASTIKFPVLVALFEEID -AGRIKLNEKLVMRRGLIAGESGTMQKPVGTKFSVLQTITNMIVISDNTATNMIIDRLGGE -TKLNQRFRNWGLQNTVIRNNLPDVGGT------NTTSPKDLVRLSALLSNNRLLSPQSRN -QVLAIMRGTRN-RSLLPAGIDKKAIISHKTGTLRF-ILGDAGIIQMPNGKSYLAGILVRR -PNYD-DGAVSFIRQVSRAVYNY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. BK036 TaxID=2512122 RepID=UPI001029D709 ------NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTQSDLTVHQPIRALVGKDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -AAINRMLATKGVAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSPRSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAVAVMIAS -TRQPIPARMRLMGDLTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadales bacterium TaxID=1978525 RepID=A0A4V1ZXX8_9SPHN --qELVSSLEALVRNFSGVAGVSVASVDEGWLI-SAGGERKLPQQSVSKLWVTMTVLDQID -QGKLSLDTPLSFTTEDFTVHQPIAALVKPGQTNVAEVIRRAMQMSDNTCNDKLLRLVGGP -DAVRDFIARRSLGPIRFGPGERLLQAAYVLDPPDGAAPLAIAGALARLKRGELLSPSSTE -WLIKTMEAAKTGRSRVRAAVPVGWSYGHKTGTGQTAGFNDVGIMTAPDGRGYAVAVMIGD -TARPVRERQLLMQQVAAAIVA-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=UPI000B824F4B -----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRISLNDPLVITRADFTLHQPVASLVKSDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRAYALAVMIGD -TPRPINERQLLMQGVVRAVVAE- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=UPI000C1BE80D --tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKETSE -IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MP--NLECRETIGEISKCIYDK- ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix campylonemoides VB511288 TaxID=1245935 RepID=A0A0C2QBK0_9CYAN -----NSQLKTLMGRYSLSPGMFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFEEVD -AGRIKLNETLVLRRDLKAEGSGILQYPVGTRLSVLDTATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNDKLLNNTSRS -KVLGIMRRVQN-RRLLPAGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-TRARVFISQVSKLVYG-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=A0A1I3UXT6_9SPHN -----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRISLNDPLVITRADFTLHQPVASLVKSDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRAYALAVMIGD -TPRPINERQLLMQGVVRAVVAE- ->[subseq from] serine hydrolase n=1 Tax=Rufibacter roseus TaxID=1567108 RepID=UPI0013725D12 ---KTEAQLREMIDASPAVTGLVAVDLTSGETF-SFNQDVQFPQASAIKVPILLEVYKQAQ -EGKFALTDVLSIEPATVVGGTGIIKDLVDTSFSIRNLAVLMIALSENTATNALIDLV-GM -QNINKTMQNMGLKQTRVQRKMIQAAAS-GRGEENISTPADAAKMLQMLYKGEFLNKATSQ -EILSILLKTDRQTSRLSAGIPQHVPLAFKPGILN-GVSTEWAIVLLPER-PYAIAIMESY -KQ--SGKAEKIMEEVSEVLYNYf ->[subseq from] Serine hydrolase n=1 Tax=Merismopedia glauca CCAP 1448/3 TaxID=1296344 RepID=A0A2T1BX38_9CYAN ----LKRELLSVVKEYSLSVGMFFLDVDTGEHI-DIGGARVFPAASTIKMPILIALFQDVD -SGRVKLNQTLVMRRKHVTGGSGTLQKRVGAKLSVLDTASRMIIISDNTATNMIIDRMGGI -ARLNSRFRSWGLRDTVMRNWLADLRGT------NKTSSKDLARVLTLVSKRRLISDGSRQ -KVLGILRRTKT-RTLLPSGIGPGARIAHKTGDIGF-LVGDAGLVEMPGGKRYVGVVFVRR -PY-DSPLARKFVKRVSRLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=UPI000A01C92C -----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_39_19 TaxID=1797957 RepID=A0A1F9X1D0_9BACT --eKLNNEMMENINKFPGEVGIYIKDLKTGVVL-SYNESKPFASASLVKIPIMAATFQAVE -DGNMSLSSKMTMLRKYKAAGSGSMKRNRKGTYTVEQLVYNMITDSDNTATNMLTYEL-GF -GYINWVFQKLGLEVTRFDRGIMDLRLR-NKGIENYTTAKEMGDLLEKMYNKKLVSKESSN -KMLDVLAHQKH-NDRIPRFLPNGLNVAHKTGLLR-GICHDAGIVFTDKGD-FIVCVLTRD -FG-SYKLAKNFIGEVAYITYRCy ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. TDK1 TaxID=453247 RepID=A0A196NGH6_9SPHN -----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLNDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A353C7Q8_9BACT --qTLSKRFGSIAEEAKGKVGVYALVLETGEFA-VLNPTERFAMQSVVKVPISMAVMKMVA -DGKLTLDTRIKIEKEEFVPHSPIRDKIPNGGLTIGELIESAVSVSDGTASDVLQRVAGGA -KGVQAFIDQLGVSGMKIRHTHKEFAADWDLQYENSITAESAVRLLQKLWDEKAASPQKEL -ILLNHMYRTPTGPNRLKGLLPPGTPVAHKTGTGRTSATNDVGIITLPNGDH--------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Bacillus cecembensis TaxID=459347 RepID=UPI00071710CF -----QQQLAQLLDDIPYRVHVIIQDYRTNQLFiEKNKDAVFSSASVIKVPILMAVLHHLE -KTNGQLSQKVPITDTNIVDFSVLTEQQ-QKKATLHELLLWMIITSDNTATNMCIDLI-GF -EALNDYFQHIGLKSTAVQRKMMDFERQ-QQGLDNVTTARDMQHLFQQIYAGTLLAREWNE -VALNILLRQRS-HESLKRYLVDDVKIAHKTGGLDT-VDHDVGIVFTEQVD-YFIGVFLTE -VT-DNDKARQYIGQISKIAYAYf ->[subseq from] Peptidoglycan glycosyltransferase n=3 Tax=Calothrix TaxID=1186 RepID=A0A2H2X753_9CYAN ---SLSSQIKSLMSRYSLDPGMFFVDLETGNYV-DYNGEKAFSAASTIKYPILIALFQEID -AGRIKLNETLTMRRDLMTGGSGTMQYQAAGTFSLLETATKMITISDNTATNMIIDRLGGR -NKLNPRFRSWGLQNTVIRNLLGDFKGT------NITSAKDLVRLSALVANNQLLSNSSRT -RVLDIMRRVKN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR -PFGD-ARGTSFISQVSRTVYG-- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermohydrogenium kirishiense TaxID=937254 RepID=A0A4R4A918_9FIRM ----LYDDIKRFINNTDGNIGVSIKNLKTGERI-DINEEMMFPSASTIKIVIMAQIFKMAK -EGYIRLTDNIILSDFMKTNGSGILYQLNSKHFTIEELITLMIIISDNTAANVLIDIA-DM -KNINKMAEDLGMLHTKIQRKMMDFEAA-KSGKDNYTCPKDMTHLLELIHDGKVVDEEYSI -KMIEILKKQQE-FGRLNLYLPDDVLIAHKPGELKS-LEHDVGIVFLKDCD-YIISVMTNN -MNTN-LDGRMAIGKISKMVYDEy ->[subseq from] class A beta-lactamase n=1 Tax=Prevotella lascolaii TaxID=1776379 RepID=UPI00083AC805 ---SLAERIDSILSGRRMTVGVSAEC-GDFSYV--RNARVRFPLMSVFKVHVAMKVLADMS -ASGTSLDTVVHVERAMLREYSPLRDARPSGDITLAGLMRYSVAESDNNACDILIRMAGGI -GQVDRYVRSLGVDGFRLMHDEDAMHRDITRCYDNWSTPEAMTRLMKIIFEGS---TPLYA -PLRSMMAATVTGADKIRAGVPESLHVAHKTGSSDKTGDNDVAVVRMPSGRNCYITVFIKD -SAETDAVNAAVIAAVAREIVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V597_9BACT -------------------------------------------------FMAASAILKESE -VKKKLLTQHVALKKSDLVNYNPSTEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RBG_16_66_12 TaxID=1797940 RepID=A0A1F9UYB6_9BACT ---KMTSQLDNLSARYPGRVSIFLSDLRSGKTW-MHHPDDLFPAASLIKVPIMIAAFYKMK -DGQLSLDERLAISRRNRVGGSGSLKWRPDGTLAVRDLLMYMINESDNTATKMILERL-GL -GYVQQQFPRIGLLYTGIYEEGMSIKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKASSE -FMMEILKRPKAVPSRLAKGLPVGWEIAHKTGLLRQ-ACHDSAVFLTPNGD-YAMTVLTGQ -NQ-SYSQAKTLITKLAHVTFANy ->[subseq from] serine hydrolase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ACAAE3 ---ELRQQIEQELARHPGVFAVAFKDLTTGQEL-LIREKELFHAASTMKTPVMIEVYKQQA -QHKLSLSDSILVKNESIVDGSPFSYKQLGTKRTLASLVYDMITVSSNLATNLIIEKV-DA -RNVTQTMRELGANDIQIWRGVEDSKA-FAKGMNNATTAYDLMVIYDKLAQGKVVSPEASK -AMIGVLLDQKF-NESIPAKLPKEVKVAHKTGSIT-GVRHDSGIVYLPDGRKYVLVILSKQ -IKD-DIETQNVMATISEWLYRY- ->[subseq from] Serine hydrolase n=1 Tax=Nostocales cyanobacterium HT-58-2 TaxID=1940762 RepID=A0A1Y0RVY5_9CYAN ---QLNSQLKTLVTRYSLSPGMFFLDLDTGNYL-DFNGEKVFPAASTIKFPILVALFQEVD -AGRVKLNETLVLRRDLKAEGSGVLQKPVGTRLSVLDTATKMITISDNTATNMIIDRLGGK -AKLNERFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLTSTSRS -QALAIMRRVEN-KGLLPSGLGKGAVIAHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-TRAKVFISQVSKLVYG-- ->[subseq from] Beta-lactamase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=R6PMX1_9CLOT ---DLENNLKFLASKYSLKPSVYVWEYESGKHA-DINSTEVYPTASIIKIPVLIQLFRSIE -AGMLKLDDKIAMTQYYKSEGSGSLQFKGNNAYTVDDLARVMITESDNSATNMLMDATGGM -NAMNQSLRKWGMKETRVNDWLPDLQGT------NVTTSKEMATLLYNIDNPNFLSLNSRE -KMVDYMSHVHN-NRLIQAGLPSDAIFIHKTGDIGK-MLGDAGIVYTPNGKKYIVVMLVNR -PYN-SPQGKDFIVAASSLIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium SW_9_44_58 TaxID=1919144 RepID=A0A2T2RGQ8_9CYAN ---SLKQTFQTLASQQQLNPAAFVVDLDSGKYV-NFQGESRLSAASMIKIPILIAFFQAWE -EGKLQLDESLTITEAVKAGGSGKMQNQPGTEYLALEAAAKMIIDSDNTAANMIIKRLGGK -EALNRLFVQWGLEHTRLRNPLPDFERT------NTTSPKELVTLLAQLSQGELVSARSRD -RIFQILGKTQN-NSLLVQGLDQRASIAHKTGSIAS-LVGDVGIIDSHTGKRYLVAVMVER -PPND-NQAKELIRRYSQETYQYf ->[subseq from] serine hydrolase n=1 Tax=Vibrio breoganii TaxID=553239 RepID=UPI00068081E5 ------KQVEAITAPLVGRVGFAAQLIGSDKII-AYNGDMTFPMASTYKVPAAVTLLKRVE -AGEVKLDDMVELHLDDMVADNVIAENFVHPGLSVANLIEPMITMSDNTAADFVISLAGGP -KAITDAMRKLGIKDMRIDRNIKDLFRKYEADPRDQSTPFAMLDLLMKIDSATAISEDSRD -FLIASMSRTRTGAGRIKGLLPRGTPVAHKTGTAT-GVAN--------------------- ------------------------ ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X665_9BACT -------LLKNVINGKQATVGVAIKNFQSGEEH-YILPDERFALMSVAKFPQVLLLLHLAD -EGKYDPKAPVSFDAEDLKQASSLRKDHPQSALPLTEALRYCIGQSDNITSNKIFELEGGP -RAVEDYVHSLGIADIGVTTDYAHMRPDSPR--QNWGTPRAMLALLEKFHNGKLLSDSSKA -MLWKAMVEATSGHNRIRGGVPAGTLVADKTGTSGTAAFNDVGIVQLPDGGYYGLVVFVGD -SKEPDSVNAAIIAGVSKTVWEHf ->[subseq from] serine hydrolase n=1 Tax=Anaeromusa acidaminophila TaxID=81464 RepID=UPI000368BF63 --kHLHTKLEQLAASCPCRWSVVVTDGDGRNVY-SLRPDLIYPSASMIKVPILFEILRQAA -AGTLCLQDPLAPSASCRVGGAGILKELNPSLLNIRDLCVLMISLSDNTATNTLIERV-GM -AAVNQTMSDLGLSHTRLQRRMMDFAAA-EAGLQNETTAADVAKLYQLLLNAQGLPPAYAA -LALNILKTQQV-RDKIPFYLPESVSLAHKTGTLD-GVEHDGGVLYLPAG-PYIVCIFADG -LQ-SNAHGLQLIAQMGRAIYDA- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=UPI000C1BE47C --tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKEASE -IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MP--NLECRETIGKISKCIYDK- ->[subseq from] serine hydrolase n=1 Tax=Mastigocladopsis repens TaxID=221287 RepID=UPI0002EE6327 ---QLNSQLKTLMARYSLSPGMFFLDLDTGNYL-DFNGEKVFSAASTIKFPILVALFQEVD -AGRVKLNETLVLRRDLKAEGSGVLQYPVGTRLSVLATATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALITNNKLLNDTSRS -QVLGIMRRVEN-KRLLPAGLGKGAVISHKTGTLGV-LLGDAGIIELPSGKRYLAGILVKR -PFGD-TRARDFISQVSKLVYG-- ->[subseq from] Beta-lactamase n=1 Tax=cyanobacterium endosymbiont of Epithemia turgida isolate EtSB Lake Yunoko TaxID=1228987 RepID=A0A077JJM7_9CYAN ------EKIASQEKYAKVKSHGWFIDLDNGNYV-NFNGDTSLSAASTIKIPVLVAFFEELD -AGRIYLDEMLTMDEKIITGGSGSMQQKPGTQFSALEAATKMIVISDNTATDMLVRRLGGK -EVLNKRFKEWGLTKTEINNHLPDLEGT------NTTSPKDLVELLALIERGDLLTVRSRD -RLLGIMQKTRT-QTLLPQGLEQGAMIFHKTGDIGT-ILGDAGIIDIPTGKRYIGAVFAER -SYND-VMGRMIIQDFSRIVYQHf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroidales bacterium TaxID=2030927 RepID=A0A4S1ZGM0_9BACT ---ALTDTLSKITSDYPGKIGVAVI-INNTDTV-AVNNKSIYAMMSVFKVHQALALCNDFD -RKGLSLDSLIAMQRDKLDPWSPMLKEHQEAELPVRELLRYTLIQSDNNASNLMFNRLVDV -ARTDSFIATIPRQSFQIAYTEEEMSADHGKAYSNYTSPLGAATLMNRLFTDSLISKDKQS -FIMETLEQCSTGKDRIVAPLKEGVVVAHKTGSGYTNAHNDVAFIRLPNGKHYTLAVFVKD -FKGNEEEAAKAIARISATVYS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A159YKG6_ECOLX ------------------------------------------------------------- --------------------------------MSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVI---------------- ------------------------ ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7VKI7_9BACT --qSLSDRIEPLIAKHQGTVCVAIKHLATGETF-FHRPQDVVPTASLIKFPVMIEYYRQVD -EGKLSGDRMVTLTQEDKVPGSGVLTDHFANSLPLETINHLMITFSDNTATNLLLDQI-GI -ANVAKTMQHLGLPETQIHSKVFRRDTSIAQDRSGSTTAADMLSLLEQLHARKLVSSEASE -RMLSHLLSCDD-KTKLLRFLPKEIKGYHKTGAVNE-SRTDAGLFDTPSGW-IAMVCLTSE -NQGDSNAAEILCGRIAQETYEHf ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=filamentous cyanobacterium Phorm 46 TaxID=2107705 RepID=A0A2T1D8A8_9CYAN -----KTQVQILATENTLTAGIFLVDLDTGSYL-NFNGDTPFASASTIKLPILVAFFQAVD -EGKVQLDQMLTLKAEHIVGGSGEMQDAPGKKYSALEVARKMIVVSDNTATNMMIELLGGA -EVLNQHFANWGLRATVLRNNLPDLEGT------NTSSPKDLINIIAQVDRGNLVSVKSRD -RILQIMRQTQN-DSLLPRGLGEGAVIAHKTGNINT-MLADAGMVDLPNGKRYLVAVMV-- ------------------------ ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3D1DR50_9PLAN ---RLAARIKPLVSRHKGQVSVLVKHLGSGRSF-AWKPDRPMPTASLIKLAVMVEVYRQVD -RDRVDLDDRLKLDEDDKVPGSGLLRKYFTTGLTLRDAVRLMIAVSDNTATNLVLDHI-GL -KSTNRTMSRLGHLNTRIHAKVFRRETSIDPDRSGSTTASETVALLEAIHQGKLVSESASQ -QMLEHLQACES-TERIPRFLPPGTVVAHKTGSVSQ-VRTDAGIIGSPAGA-IVICVLTSE -N---------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. 43_108 TaxID=1896974 RepID=A0A1Q6HCJ8_9BACE --dSLENRLNEAIAGKNAEIGIAVIA--GKDTV-TVNNDAEYPMMSVFKFHQALATSDYLR -THGLELNDTIHISKKELKEYSPLRDKYPNGNITYAELMEYTLQQSDNNACDILFQRTADL -CRTDSFIRTLGIDKFAISVNENDMHVDPKLCYSNWTTPLEAAKLIDAAFTREIVPDPYLS -FIRNTMSNCTTGKDRLPFPLEKDASIAHKTGTSDRDAINDVGYISLSDGRHYSIAVFVKN -SKESDSETAGIIAEISEVVYDY- ->[subseq from] FRAMP1.1 beta-lactamase (Fragment) n=1 Tax=uncultured organism TaxID=155900 RepID=I0AXW7_9ZZZZ --qDAERRISEMTAGKPAEVGVAWIA--DGKAH-AVNNADGYPMMSVFKLHGAVAELRQME -RRGTPADTLITVRAAEMEKYSPMLKRYGGRDIRLDSLLRYSVAESDNNACDIIMRLAGGT -DGVNAEMRAIGLTGYAITETEASMHADPTRSYNNRSTPLAVAELFRKLYEGGILGEPYAT -LLKDILLSTSTGPNKIKAALPPGATLAHKTGTGFITADNDAGAITLADGRRIYIAVLVKD -SKLGADGNARLIKEIAEAVI--- ->[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus sp. OK032 TaxID=1884358 RepID=A0A1H9RFP2_9BACI ---TLQQRIESYIHDIDATFGIYIKHLGTQEEV-NIQGNQLFQMASVFKVPILATLYEKVN -NGEINLHERIRLNEEDYVPGSGVFQEMQYGIPTIKDLATMMIIVSDNLATDKVLSIVGGA -DHVQERMHQMGLNDIYIKHTCWELLSFQNSTGNNVSSAKDMSLLLEKIALDEFISPDCSR -EIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MYNDAGIVYLPDNGEFVITVYSTG -SSLE-YKGDEPIARIAEIAYQYf ->[subseq from] Beta-lactamase TEM n=1 Tax=Solibacillus isronensis B3W22 TaxID=1224748 RepID=K1KHN5_9BACL -----HKQLDRIIAQCPYKVHVIVEDYKTDEIVwKIRAEEIFSSASIIKVPILIAILAHLQ -KTNGSLNQVFKISPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM -DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA -VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFLEVRD-YFIGVFTTE -VT-DNDKARQTIGAISKIVYEHf ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JKB7_9BACT ---------TRIAQDSGAYAGVAYIDLGSSDTL-FVNPDSSFHAASTMKVPVMIELFRRAN -TGSFRMDQGLMMVNQSLADGSPYSYHRIGERVRVDSLLRLMITRSSNFATNTLITLV-GA -DAVTKTMRVLGARRIQVRRGVEDGK-AFQAGLNNTTTARDLAIIMRAIEDGKAAPPDATQ -QMLAIMLAQEF-NEKIPAGLPPGIRVAHKTGDIT-AVSHDAAIVYPPGRQPYVLVVLTRG -IT-DGAKSAKLIADISSMVFSH- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7RG39_9BACT --qSLSDRIEPLIAKHQGTVCVAIKHLATGETF-FHRPQDVVPTASLIKFPVMIEYYRQVD -EGKLSGDRMVTLTQEDKVPGSGVLTDHFANSLPLETINHLMITFSDNTATNLLLDQI-GI -ANVAKTMQHLGLPETQVHSKVFRRDTSIAQDRSGSTTAADMLSLLEQLHARKLVSSEASE -RMLSHLLSCDD-KTKLLRFLPKEIKGYHKTGAVNE-SRTDAGLFDTPSGW-IAMVCLTSE -NQGDSNAAEILCGRIAQETYEHf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas azotifigens TaxID=330920 RepID=UPI000A025FC1 ---ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPNPQQSVSKLWVAIAVFDAID -HTRMSLATPVTVTRSDLTVHQPIRPLVGPSGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLIGHASTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQSIPVRMRLMGDVTRAVIR-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3NW79_9FUSO ---EWKKEIKKIISEVKGQVSVSFYDLDKNMAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILMDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKETSE -IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MP--NLECRETIGKISKCIYDK- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A522QFQ7_9BACT ---QLQMRLDTLARHAPGDVAVAVRDLRTGEVV-GYNAHASLPAASTIKVPVMVEVFRQME -AGAFALDRDVSLTSADRDGWGDLADAPANSHYTVRRLLWLMITQSDNTAANMLIRLV-GR -AHVNETMHALGLGNTSLSDYIRSYGDI----RSIRTTASDMVRLMAMIAHGQLVDEWSCG -EMLQIMAGQHI-NTLLPEPLPADVLVAHKTGSLHD-TLNDVGVVYLA-GAPYAIAVMTTH -LA-SLDSGRAFIHAVSSLTFK-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFI2_9BACT ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRRLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWT----------------------------------- ------------------------ ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3N5ZUU7_9BACT ---QFAVRLEDIARRVDGVVGYCVVDLTSGTRF-TRLETEVFPTASTIKLAILYELFAQAQ -EGRLALDKPLTLDRAAAVGGSGILFEMGTPTLSLRDYAVLMVVLSDNTATNVLIDAV-GM -ANVNRRMQGLGLTETRLRRKMIDLAAARRG-DENVSTPGEIARLLEAYHKGTGLEPPTVA -AALAILKKGKD--SWLVRAVPSSVPVASKPGDLE-GVRVDAGIVYVPKR-PFIITVMTSW -LQRD-EDGERAIEDLSRAAYQYf ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium canifelinum TaxID=285729 RepID=A0A3P1UYS9_9FUSO --tEWKKEIEKIISQVEGKVSVNFYDLNKTDGF-SINGNEKVLSASIIKLLILAELLKKAS -ENKFSLSDTITITNFMKTEGDGVLKELNTGHFSLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKETILERRMMDTEA-RKNGYDNYTSADDISLLLKRIYQEKLINKEASQ -VMLDILLRQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWFGDKA-YILVVLTSG -MS--NLQCKRTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Sporomusaceae bacterium TaxID=1917525 RepID=A0A402BNM3_9FIRM --eELRQKIWGILETYTGHFGLVLMNPTTGARL-ELNPTLPFPAASMIKVPIMYEIMRQAA -ANTLSLEDTLIVTNEVCVGGAGILKELRPNLMTVKELITLMIIVSDNTATNMLIDLV-SM -KSINDTMAALGLTATCLKRRMMDFAAA-QKGHENTISAADLALLYAKLLTGSEIPMSYNH -LMLDILKRQQI-RDKLPFYWPEETVLAHKTGTLA-GVEHDGGILFFPGG-PYIVVVLTGN -LDAN-YRGLQLVAEIGQVLYDHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A140IK99_ECOLX --------------------------------------------------MAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIR------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SG8_28 TaxID=1703357 RepID=A0A0S8B8R5_9BACT ---SLQTAIEHHAATSGATVGVYFRDLASGDSL-LFDADARMHAASMMKVPVLIQLFRDQD -AGRLSLDDSVVITKTSIVDSSTFDYARIGERASIASLAERMITVSSNLATNMLIELV-GA -ARVQATMRELGADSIAVLRGVEDIK-AYEAGLSNTTTARDLGAIFTAIAAGTAASAESCR -EMIAILERQEF-NEGIPAGVPSEVRVAHKTGWIS-GIRHDGGIVTLPDGRRYVLVVLTRG -IA-DVAVADSLIVDVSRLVYD-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas elodea TaxID=179878 RepID=UPI000A0304A3 ---ALLNAVQALGAGFQGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HARLSFATPVTVTRSDLTVHQPIRALIGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLAQDKLLSHGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPDGHRYAVAVMIAS -TRQSIPVRMRLMGDVTRAVIR-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3PY58_9FUSO --tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILMDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINKEASE -IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MP--NLECRETIGKISKCIYDK- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2G9EDV6_9FUSO ---EWKKEIKKIISEVKGQVSVSFYDLDKNMAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAKLSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLKLIYEGKLINEEVSE -IILDILLQQQQ-SERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MP--NLECRETIGEISKCIYDK- ->[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. WM24 TaxID=2558278 RepID=A0A4Y9J486_9BACT ----MEHRLSEYVSGKDATIGIAVI-INGNDTV-AVNGDKDFPMLSVYKFPQALAVADYCK -RHDIGLGDTVAVKATELKIWSPLRDKYGISDVTINELLEYTLQLSDNNACDILFRLIGGT -QAADSLMKSMGYNDIHIISTEDEMHKDLSLCYLNSSTPIAMARLFDRFYREERNGLNTHR -VIGEIMTSCTTGANRLPAPLKSDAIIGHKTGTGDTNGINDAGVVYLPDGNTYSIAVFIKD -SAYDMAETEKMIAEISELVYK-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Chlorogloeopsis fritschii PCC 6912 TaxID=211165 RepID=A0A3S0Y2Q8_CHLFR ---QLNSQVKALMARHSLQPGMFFLDLETGNYL-DINGEKVFPAASTIKFPILIALFQEID -AGRVKLNDTLVMRRDLMTGGSGTMRKRAGSKFSLLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRTWGLQNTIIRNLLGDFKGT------NTTSAKDLVRLSALITNDQLLSSTSRS -KVLDIMSRVQN-RSLLPKGLGKGAIISHKTGTLGI-ILGDAGIIQMPTGKRYLAGIIVRR -PFGD-ARAKSFISQVSRLVYG-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A3S0EFR0_9BACT ---ELRKKIEVVATMKDLRAGVFAADLKTGKFV-DYNGHDEYAAASMIKVPVYVSLLTALD -RKEVSLDQPVEIRQDLVTGGSGWLQWRPGTKVPLREVAELMIIISDNTATNMVIDLLGGK -EKCNRDYVSWGLQKTRINNMLGDFEGT------NKTSPYDMVYLLSRIDRGEIISPESRK -WMYQTMERTRI-RTLLPPGLAPGSRILHKTGDIGT-MVGDAGIVITPTGQRYIVSMQVER -PHND-RRANLLIRALSKMVYRCf ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. C21 TaxID=2302915 RepID=A0A372F5J4_9BACT --eKFKNEIQAKLSTVEGEFAVAFKDLQTGKTL-FINEKDNFHAASTMKTPVMIEVFKQAR -AGKFKLSDSIVVKNESIVDGSSYSYKKIGRKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KNANATMRTLGANDIQVLRGVED-NKAFKLGMNNTVTAYDLMTIFEKLAQEKVVSPEDSK -GMIKILLDQKF-REKIPAKLPAEVKVAHKTGSIT-GVQNDSGIVYLPDGRKYVLVLLSRK -LK-DEKKGVEALADVSRMIFDNf ->[subseq from] AMIN domain-containing protein n=1 Tax=Anabaena sp. 4-3 TaxID=1811979 RepID=UPI00082A8AAF ---QLESQIKSLMRRYSLTPGMFFLDMETGEYL-DINGEKAFPAASTIKFPVLVALFQEIE -AGRVKTNETLVMRRDLMTGGSGNMQQKPGTKFNLLETATRMMTISDNTATNMIIDRLGGK -NRLNERFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLAALISNDKLINRNSYA -QVMDIMRRCKN-RSLLPVGLGKGAAIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGILVGR -PFRD-ARAKSFINQVSRLVYG-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Anabaena sp. (strain CA / ATCC 33047) TaxID=52271 RepID=UPI00082F20EF ---QLESQIKSLMRRYSLTPGMFFLDMETGEYL-DINGEKAFPAASTIKFPVLVALFQEIE -AGRVKTNETLVMRRDLMTGGSGNMQQKPGTKFNLLETATRMMTISDNTATNMIIDRLGGK -NRLNERFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLAALISNDKLINRNSYA -QVMDIMRRCKN-RSLLPVGLGKGAAIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGILVGR -PFRD-ARAKSFINQVSRLVYG-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas elodea TaxID=179878 RepID=UPI000C1E13D4 -----VNRLSDIAHNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLSDPLVITRADFTLHQPVASLVKGDQSTVGEIMRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Beta-lactamase class A n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=R7ZA24_LYSSH -------LIRQLLQETPYKVHIIVKDLRTDETLiSERSTEVFSSASLMKVPILLAVLHHVE -TNRLTLDEVLMITPKDWVDFSVISEQQLKS-ATIYELLVWMIITSDNTATNILIDYM-GM -DALNCYFRENGLKHTILQRKMMDVVRR-ANGVDNVTTARDMAHIFTHIYRQDLFTPSFSA -LAIDILSRQRV-HEALSRYLVDDVIIAHKTGGLET-VDHDVGIVYSDAK-DYLIGVFVTE -VTN-NQEARQLIGRISKVVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Neosynechococcus sphagnicola sy1 TaxID=1497020 RepID=A0A098THL1_9CYAN ---DLQPQVQAVIQRYSLKAGMYFVDLQTGNYL-DIQGDRVFPAASTIKLPILIAFFQDVD -AGKVSLHETLVMRRDLIASGSGDMQDMPGSKFSALETVNKMITISDNTATNLIIDRLGGI -ERLNQRFRSWGLQDTVMHNWLGDFQGT------NKTSSKDLVRLLALMINGRLVSDSSQE -QVLRILRHTTV-KTLLPSGLGPGAVIADKTGDIGF-LVGDAGVIDMPNGRRYLAGIFVLR -PYND-PIVRRFVREISHLVYAY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobium sp. RSMS TaxID=520734 RepID=UPI0010F9CFAA ---NLLNAVQRLGEAFDGQVGISVRDMDEGWTV-SFNGDRLVPQQSVSKLWVAIAVMDAVD -HGKLSLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGHLLKMALTRSANSCNDVLLWKVGGP -KAIRAMLARKGVDDVSFGPGERKLQARYLAAPYDGASADGITRGLMLLKKGKLLSAGSTR -HLLSLMRASRTGPLRLRSGLRDGWTLAHKTGTGQSTGYNDVGILVSPEGHRYAVAVMIAT -TRVPIPTRMRLMGNVTRAIIR-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. ATCC 53789 TaxID=76335 RepID=A0A367QQ51_9NOSO ---ELKTPIKALMARYRLTPGIFFMDLKTGDYF-SFNGDKAFSAASTIKYPILIALFQEVD -AGRIKLGETLVMRRKHVTGGSGDLQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV -SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISDRSQS -QVLGIMIRCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=UPI000CD8979B ---KALDELAHRAEGRGGVLGVVVQS-ANGEYA-SVNADRAFTAASLIKLPVMLALLDGVE -AGRWSLDDRLPVR--DRVGGAGILRDLADVALSVRDLVTLMIVISDNTAANLLIDRI-GA -PAVADWCGRHGLRATVLERRMMDAEAR-ARGAENRTSPADMAKLLDGLVRGTLLGPAMTA -FALDVLARQQV-RDRLPRYLPAGLRIAHKTGELD-GLRHDVGIIFTN--APIIVAALTEN -AD----EADDLIAESARRAVQ-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI00141018D5 --dQLRQQINQELAKQSGVFAVAFKDLGTGQEL-FIREHDVFHAASTMKTPVMIEVYKQVA -QKRLSLSDSIPIKTESIVDGSPYSYKEVGTKRTLVSLVYDMIILSSNLATNLVIEQA-DA -QKVTQTMRELGAKDIQVRRGVEDSK-AFEQGLNNTTTAYDLMVIFEKIATGQAVNPEASK -AMINILLDQRF-TSKIPAKLPKEVKVAHKTGSIK-GVSHDSGIVFLPDGRQYVLVLLSKD -LKND-QAAEDTLATVSELIYQY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=UPI000B8501B0 ---ALLNAVQALGTGFQGQVAISVRDVDRGWMV-AWNGERPHPQQSVSKLWVAIAVFDAID -HQRLSLATPVTVTRADLTVHQPIRALVGPTGTTIGALLECALTRSDNTCNDVLLWKVGGP -TAIRRMLKEKGVDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLARDKLLSHGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVIR-- ->[subseq from] Beta-lactamase class A n=2 Tax=Stigmatella erecta TaxID=83460 RepID=A0A1I0KDR4_9DELT ---------QRIAQVKGASVAVAYLNLGDSRDTvFLGAEASFHAASTMKVPVMIEFFRQVD -AGKLSLDQPVPLANRSIVDGSPYTYERLGQAVPASELLKRMITRSSNLATNTLIARV-DA -KRVTRTLRALGARSMTVLRGVEDAK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ -AMREILLAQEL-NTLIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPPGRAPYVLVVLTRD -IP-EAPVAEALIVDLARQVHA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V596_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNAAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSICAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8U3R1_9BACT ---KLESTLDRLASELRGATGYVIRDLDSGETF-EKSGDAIFPAASTIKLPIFIELYKRAE -EGGIDLERPVPIDPKARVEGGGVLEKWSAPYLSARQLSVLMIDFSDNYAANLLTDLV-GM -ESVGRRLRSWGFEDTLLRRRMMDLGAA-RAGRENVTTPRDMAGLLERLQRGQLLNAENTR -AVIDVMKRNEG--TPIKRGLPPGAEAADKDGELE-GVRCDAGLVFVKGGRPLVIAVMTAY -LE-DDAAGEAFIGEVTRAACQY- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI000BFCB17A --tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGNEKVLSASMIKLLILAELLKKAS -ENKFSLSDTITITNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKETILERRMMDAEA-RKNGYDNYTSADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_50_26 TaxID=1797960 RepID=A0A1F9WTY4_9BACT ------AELQARAEKFPGEAAIVIKDIQTQQEI-GINVARLFPSASLVKVPIMAAVYQAQE -EGKLRLEDHIILKKKHKVRCSRLYNMRPGRKVVIRDIIERMITESDNTATNMLVDAL-GF -GYLNQKFIEFGLKQTDLRRGVMDLKW-RKAGIENYTTAADMALLLEKIYNGELVSHAASA -EMLEVLKRQKV-NDRIPRLLPDGLVIAHKTGLLND-TVSDVGIVFTKEGD-FIICVLTAD -IK-SFLSAKKFIGSVAACAYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Anseongella ginsenosidimutans TaxID=496056 RepID=A0A4R3KNA2_9SPHI ----LRERIISRLEAENGTFAVAFHDMDTGKEL-LFNEREVFHAASTMKTPVLIEIYKQAA -EGKLSLDDSLLIKNKSIVDGSLYRYKRIGEQVPLKKLLYKMIIRSSNLATNIIIELA-GA -ENVTKTMRNLGAADIRVLRGVEDLK-AYEKGLSNTTTAFDLLRIYQKMASGEIVSPEASK -AMISTLLDQEF-DRIIPAGLPEDVKVAHKTGSIS-GVRHDSGIVFLPGGRTYVLVLLSKD -LE-DAEAGIAAMADVSEMIYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A9_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGMTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERGTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E7UC23_9SPHN ------------------------------------------------------------- -------------------------------GISGREHLDLMISRSCNDCTDALLKAVGGP -RAVNAWMRQAGIHDFELTRDIATLVRASQIAFEDSATPRAMGRLLAGIYQGKWLSSYSRQ -VLMNAMASTVTGKRRMTSALPDSANLAHKTGTLSR-TASDIGIFYTPDGRPVAAAIYVTG -QSVSMASEN-------------- ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1NBP0_9CYAN ----LNSQIQALMARYSFLLGMFFLDLQSGDYL-NINGDKAFPAASTIKFPILIALFQEIE -AGRVRFDESLVMRRDLVAGGSGDMQQSVGSRFSVLQTATKMMTISDNTATNMIIDRLGGK -AVLNQRFQSWGLKNTTIRNLLADVNGT------NTTSAKDLVRLSALVTNDKLINNTSRS -QVLQIMRQCHN-QSMLPSGLGSGAIIAHKTGTLRF-VLGDAGIIQTPNGKIYLAGILVKR -PNHD-SRATEFIRQVSRFLYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Chrysopegis kryptomonas TaxID=1633643 RepID=A0A0P1MZL5_9BACT -hkKTFEKIKFIADTSNGVIGVAIKNLATGETF-LINENLLFPQGSAIKIPILVEVLKQAN -EGKFKLTDKIKIEKKYQVGGSGVLKEFGDGLLSIYDLAVLMITVSDNTATNILIDLV-GM -ENVNKTLEKLGFKNTKLQRKMIRPDAS-ARGEENLSTPFEAMKFMEMLYKGQIVSKEISE -QAIKILKKEKE--ANLNKYLPQNIEIANKPGGIE-GVTCEWGIVFLPRH-PYVIIIMSNY -NL---TSAGETIAQISKIAYEHf ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. 17J42-9 TaxID=2492393 RepID=A0A4Q5LVL9_9BACT --eKLKDAIQAKLATVEGEFAIAFKDLQTGQTL-FINEKDNFHAASTMKTPVMIEVFKQAR -AGKFKLSDSIVVKNESIVDGSPFGYKKIGKKMTIYDLTYQMIIVSSNLATNILIDLV-EA -KKANATMRTLGANDIQVLRGVEDSKA-FKLGMNNTVTAYDLMTIFEKLAQKTVVSKEDSE -GMIKILLDQKF-REKIPAKLPKEVKVAHKTGSIT-GVQNDSGIVYLPDGRKYVVVLLSRK -LK-DEKKGVEVLAEVSRMLYD-- ->[subseq from] Beta-lactamase n=2 Tax=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) TaxID=479434 RepID=D1C5R0_SPHTD ----------AAAEATGGTVGATIVA-PGGETF-RHNGDRRFRAASTVKIPLMIAVYRAVD -AGERALTDRIVLRAADKAPGSGVLLHHDGLELTLEDLVYLTISISDNTATNLLIDLV-GL -DAVNDVIASLGMRDSNLSRKMKGRP-ALPDEPENWATPDDYALAVQALLEGRAASQESCT -AMLAMLEKQQN-PRRIGRYVPEGIRWGSKTGSLT-GVVNDVGFITTPAGT-LVVAVFTEN -LP-DLHAGEQAIGDITRAALQ-- ->[subseq from] PenP, beta-lactamase class A n=1 Tax=Nostoc sphaeroides CCNUC1 TaxID=2653204 RepID=A0A5P8W169_9NOSO ------LPIKALMARYRLTPGIFFMDLETGDYF-SFNGDKAFSAASTIKYPILIALFQEVD -AGRIKLGETLVMRRKHVTGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV -SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALITNNQLISDTSQS -QVLGIMIRCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] Uncharacterized protein n=2 Tax=Calothrix desertica TaxID=32056 RepID=A0A3S1AMW2_9CYAN ---QLSSQVRSLMSRYSLDPGLFFIDLETGNYV-DYNGEKAFSAASTIKFPILIALFQEID -AGRVKLNETLTMRRDLVTGGSGTMQYRAPGTFSLLETATKMITISDNTATNMIIDRLGGR -NKLNPRFRTWGLQNTVIRNLLGDFKGT------NITSAKDLVRLSALVANNQLLSNSSRA -RVLDIMRRVEN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR -PFGD-RRGREFISQVSRTVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D6UNZ1_9SPHN ----LERQIAQLADGSNGRIGVYAIDLATGREI-GVLADQRFPMASTSKVAIAATFLAGVD -AGKWSLTSEFRLPR-------------PGGAMPAHRHLSLMISKSCNDCTDALLNAVGGP -RAVNKWMQEAGIEGFQLSRDIATLIRAWSVXTKDXATPRAMGQXLAGIYQGXWLSDYSRR -VLLDAMEXTTTGKRRMRSALPLSANLAHKTGTLAR-TASDIGIFHTPXGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus parviboronicapiens TaxID=436516 RepID=UPI000D3BF00A -----EQMLPQLLQKSPYKMHMIVKDLSTDEIIiSERYDDVFSSASLIKVPILLAVLHHVQ -TNKVALHQVLTISPKDWVDFSGISEQQLQA-ASIYELLVWMIITSDNTATNVLIDFM-GM -NVLNRYFREIGLTHTILQRKMMDFER-LANGVDNVTTARDMTHIFTHMYHQDLLMPSYSA -LAIDILSRQRV-HESLRRYLIDDVTIAHKTGGLET-VDHDVGIVYSDAK-DYLIGVFITE -VTNN-QDARQLIGRISKVVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. CAG:714 TaxID=1262749 RepID=R6YU04_9BACE ---SLRQELANRIKNCRAQVGAALV-VDGKDTL-TLFNEVPYPLMSVYKLHQAMAVGKYLH -ERGRTSESRIAIGKEDLKPYSPLRDKYPDGNLSVRELLEYTLQWSDNNACDILFAHTGGT -AETDRYIRSLGLKEFAISSTEDEMHRDLDKCYDNWSSPLEMARLLEILFTTDLEMGEFQP -LIRQILMTCRTGLNRLPKPLENGAQIAHKTGTGDKNGINDAGMVFLPDGRRYTLVVFVKD -SWESMEKTEQLIADVSEIVYRY- ->[subseq from] serine hydrolase n=1 Tax=Varibaculum timonense TaxID=1964383 RepID=UPI0009BB49C7 ----INKKIFSIIRCLEGEIGLYFEDLQTGEKL-TINSDNIFPAASTIKIPLVLFLFQIVE -DGMLDLNDVVSISKDNRVMGTGIIKDLNENYPTILDLATLCITVSDNIAANQIIDLVGGT -SKVNEFCKKIGLSNTRLQRKMLDIE-AIKAGKDNYTTAGDMGSLLRQLGKNKIVSKQVSE -RVIEIMKTQQF-RQKLPALIPAVVVVANKTGDLR-GVQNDVGIFIMPGNNIYILAILICS -LAED-SQGIEAIAKISKVVYEE- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098F8457 ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus canaveralius TaxID=1403243 RepID=A0A2N5GGI2_9BACI ---SLQNRLEEVLHDATGNFGVYVKHLESGETA-AINQNRFFQAASVFKVPILATLYRDAE -MNRVDLHQRIRLEEKDLVNGSGIFRELIPVEVTIKNLATMMIIVSDNVGTDKILQII-GK -ETVNQYMKEIGLNNTYIRFSCWELLCFQESIENNVTTAADIAKLLQLIASKQLISQHACD -DMFEILAKQQF-RNRIPNLLPENTIVGHKTGTVAS-VVNDAGIVKLPDKKGTLIITAFSI -GNKTEAEGARKIAELSKAAYDHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium sp. LB126 TaxID=1983755 RepID=A0A2M8QW85_9SPHN ---DLLNAVQGLSASFKGRVGISVRDIDEGWTL-SSNGDAPLPQQSVSKLWVAITVMDAVD -RGKLSLSDPVTVRRSDLTVHQPIRPLVTKAGTTVGKLLEMALTRSANSCNDVLLWKVGGP -QAVRDMLARKDIDDVGFGPGERELQARYLAAPYDGASANGITLGLALLKRGELLSRKSTN -HLLALMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILVSPDGHRYAVAVMIAS -THEPIPVRMRLMGNVTRAIIR-- ->[subseq from] Uncharacterized protein n=1 Tax=[Clostridium] symbiosum ATCC 14940 TaxID=411472 RepID=U2BDQ5_CLOSY --eELKNRINEFIESQTGNICVSLFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC -AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM -DRINGMAAELGLKEAVLGRKMMDSEAK-KQGCDNFICADDIMLILKKIYEGSCVNRKASA -LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG -VK-TNKDGREAIGRISQIIYEE- ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter luteus TaxID=572036 RepID=A0A1T5B9D6_9SPHI --eKLKEQIKAELAKQKGTFGIAFKNIQTGEEI-LINERINFHAASTMKTPVLIEAYKQAE -AGKFNIDQPILVKNESIVDGSLYSYTKVGTKLPIYDLLYLMIIKSSNLATNIIIDLV-GA -QNANKTMRELGAHDIQVLRGVEDSK-AFQKGMNNTTTAYDQMLIFEAMATGKIVNKKSSD -AMIKILLDQAF-NDKIPAQLPKNVKVAHKTGWIK-GINHDAGIVYLPDGRKYVLVLLSKE -MT-DDKAGVAAMANVSKMVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Saccharicenans subterraneum TaxID=2508984 RepID=A0A3E2BQV0_9BACT -----SRQILQRISSFRGETGLVVKDLQTGWTF-LHNDEARFPAASLIKIPIMVACFKAVE -DGRLDLGEKYVLRRQDRVGGSGLLRRMRNGRFTYAELIDYMVTHSDNIATNVIIKRL-GF -DYISGVFEALGLQDTVLNRLMMDFRAR-EDGLENYTSAREITGLLEMIYHGRCLNASISE -KCLDVLKRQKI-NDRLPRFLPREALVAHKTGQERE-VCHDAGIVFSPHGD-YIITVLVRT -WSGP-LTTKTFIARLSSYFYQVf ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5XP66_9BACT -----------IATRLDGVMSVAILDLTDGRIL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKGKLDDSYTFDPKDLVEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAATNILIDRV-GR -DNVNATLRGLGLTKTMLRRKMMDIGAARRG-DENVATPQEMVRLLEMIYKGKALNKELTD -ELIKRLKTLKK-DSYLSYELPAGVELADKPGTLD-GVRNDSGIVFAPNR-PFAISVMTAY -DR-DEKAAERAISEVALEAYRYf ->[subseq from] class A beta-lactamase n=1 Tax=Brevibacterium sp. VCM10 TaxID=1381751 RepID=UPI000470BB8B -----------------------------------------------------AELLDRTT ---PKELEKNVSWTQADVDEWTPVTEKHVDEGLPLEDVAESALRVSDNLAMNIVLDELGGP -EALDDALEKNGDMTTEVTDEEPELNDVEDGSTDNTTTPAAITADLQSLLDPQRFSDDDRR -VLFDWMSANETGDPLIRAGAPEGWVVRDKSGHSD-AIQNDIAVVTPPDRQPIVVSVMTEA -DDPESEDGPALVAAVAEAV---- ->[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011EBC46E ---TLTQKISAELTKHKGYYAVAFSESSSGKTV-FINEREFFHAASTMKTPVMIEVFKQAN -AGKFSLTDSVTLKNESIVDGSLFRYKRIGKKMVIRDLVYEMITVSSNFATNMLIDLV-GA -GNVTQSMRELGAKDMKVLRGVEDTK-AFEKGLNNTTTAYDLMLIFAKMAQGEIVNQKASK -AMIEILLDQKF-GTVIPAKLPADVKVAHKTGAFGK-VRHDSGIVYLPNGRHYSIVILSRD -WE-DEKETLELLSDVSKMIYD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Calothrix TaxID=2619626 RepID=A0A2H2XYN0_9CYAN ---TLNSQIKALMSRYNLSPGMFFVDLQTGDYI-DINGNKAFPAASTIKLPILITLFQEIE -AGRVRPDETLVMRRDLVAGGSGDMQNRVGSKFSVLQTATKMMTISDNTATNMIIDRLGGF -YRLNERFRTLGLQNTALRHLLADEYG------TNTTSAKDLVLLSNLIANNQILSDASRN -QILDIMRRCHN-QSMLPSGLGAGAVIAHKTGTLRF-VLGDAGIIQTASGKRYLAGILVRR -PNHD-ARATTFIRQVSHIVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A4P5WCD4_9BACT ---QMEDSVRLIAKGTDAVVGVAILDLTDRRAF-YLNADAVYPTASTIKLAVLAELYRQHA -RAGAKLGDLYTIDSKDVVGGSDIMGGLTAGVVTNRDLATMMMAVSDNAATNVLINRV-GM -DNVNSWLAGLGLKNTRLRRQMMDVQAA-QAGRENTATPRELVLMLETLHKGDALGKTGTE -DFFKMLGTGKM--SYLPRLLPDGVRTANKPGDLD-AVRNDAGIVFAPNR-PFAIAVMTTF -GR-DHREQEMAIARISRTAWSYf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas sp. NFR04 TaxID=1566283 RepID=A0A1I3MT09_9SPHN ---ALLNAVQALGTGFQGQVAISVRDVDRGWMV-AWNGERPHPQQSVSKLWVAIAVFDAID -HQRLSLATPVTVTRADLTVHQPIRALVGPTGTTIGALLECALTRSDNTCNDVLLWKVGGP -TAIRRMLKEKGVDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLARDKLLSHGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVIR-- ->[subseq from] serine hydrolase n=1 Tax=unicellular cyanobacterium SU2 TaxID=1981054 RepID=UPI000A19BF15 ------EKVAAQEKYANVKPTAWFIDLDNGNYV-SLNGDAPLSAASTIKLPVLVAFFEALD -ARKIHLDEMLIMDKEIITGEAGTMQYQPPGTFSALETATKMIVISDNTATDMLIRRLGGK -DVLNQRFKEWGLTNTVINNRLPDLEGT------NTTSPQDLAKLLARVERGDLLTLRSRD -RLLGIMQKTRT-RTLLPQGLEQDAIISHKTGDIGT-ILGDAGIIDIPTGKRYVGAVFAER -PYND-VKGRMVVQDFSRTVYQHf ->[subseq from] Serine hydrolase n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A3A9BIT8_9BACE --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPIMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf17 TaxID=1735683 RepID=UPI0009EB30B8 ---ALLNAVQALGSSFQGQVGIAVRDVTDGWVV-GYNADAAMPQQSVSKLWVAIAVMDAVD -RGALSLSDAVTVRQSDLTVHQPIRARVGADGTTVSALLDCAMTRSDNTCNDVLLWKVGGP -TAIRRMLTAKRIAGVSFGPGERVLQARYLAAPYDGASANGITLGLALLQRGELLSNASTV -HLLTVMGASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLRSPDGHTYAIAVLIGS -TRRPIPARMQFMGNVTRAVIQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. vincentii 3_1_36A2 TaxID=469604 RepID=C7XRW9_FUSNV --tEWKKEIEKIISQVEGSVCINFYDLNKNNVF-SINGDKKVLSASTIKLLILAELMKKIS -ENKFSLSDTIMIADSMKTGGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas pituitosa TaxID=99597 RepID=UPI0009FD978F -----VNRLSDIAQNFDGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLSDPLVITRADFTLHQPVASLVKGDQSTVGEIMRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGSIRFGPGEKLLQLRYVADPPDGAAPLAIAGAIARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. NIES-3756 TaxID=1751286 RepID=UPI00071EF13D ---QLDAQIKQLMNRYSLSPGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFQEID -AGRVRPNETLVMRRDLMTGGSGNMQYRKAGTFSLMETASKMMIISDNTATNMIIDRLGGK -NRLNQKFRSWGLQNTIIRNLLGDFKGT------NKTSPKDLVRLAAMISNNKLLSLNSNA -QVMDIMSRCKN-RSLLPVGLGKGAVIAHKTGTLGR-VLGDAGIIQTASGKRYLAGIMVAR -PFGD-ARAKAFINQVSRLVYG-- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A377UTU8_KLEPN ------------------------------------------------------------- ----------------------------------------------------------AGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Uncharacterized protein n=1 Tax=Lucifera butyrica TaxID=1351585 RepID=A0A498RDJ3_9FIRM --kELRHKVQSVLSGAGGRWSIVIINQATRERL-EINPAMVFPAASMIKVPILYELMRQVA -AGQLSLDESLIVAGASRVGGAGILQELRPDIMTLRELAILMIVLSDNSATNLLIERV-GM -NAVNQTMTALGLTSTVLRRRMMDFEAA-RTGRENETCATDLALLFELIYTSHGLPDQYGA -LMVDILKRQQI-RDKLPFYLPEETILANKTGTLP-GVEHDGGILFLPGG-PYIICVLSGD -LTFN-YQGIQLIARIGKIVYEH- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5N3F0_9BACT --kKLETRVDEIANRLDGVMGVAILDLTDGRVL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKARLDDIYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVTVSDNAAANVLIDRV-GK -DNVNAMLHSLGLSKTMLRRKMMDVAAA-RRGEENVATPQEMVRLLEAIYKEKVLDKQATA -EFIKQLSTSKQ--SYIPRYLPENVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY -DR-DEKAAGRAISDVALEAYHYf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LQ49_9BACT --kKLETRVDEIANRLDGVMGVAILDLTDGRVL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKARLDDIYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVTVSDNAAANVLIDRV-GK -DNVNAMLHSLGLSKTMLRRKMMDVAAA-RRGEENVATPQEMVRLLEAIYKEKVLDKQATA -EFIKQLSTSKQ--SYIPRYLPENVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY -DR-DEKAAGRAISDVALEAYHYf ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus gallinarum TaxID=1293 RepID=A0A380FCU8_STAGA ------------------------------------------------------------- ---PQDLNQKVTINKSDIVTYSPVTEKYIGKTMTLRQLIEASMLKSDNTANNKVIQAIGGV -NAFKSELRQLGDCVSEPQRLEPDLNNYDPKKIADTTTPRAAATTLNYILTHSNMHKGNLQ -FLKELMIKNETGDSLIKAGAAKDDIVGDKSGQGTYATRNDLAFIYPKGQKPIILAIYTKQ -SDKNAKPNDEVIAKTAEIAIKY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. V33-4 TaxID=2054169 RepID=UPI000C78E850 ---SLQNRLEEVLHDATGNFGVYVKHLESGETA-AINQNRFFQAASVFKVPILATLYRDVE -MNRVDLHQRIRLEEKDLVNGSGIFRELIPVEVTIKNLATMMIIVSDNVGTDKILQII-GK -ETVNQYMKEIGLNNTYIRFSCWELLCFQESIENNVTTAADIAKLLQLIASKQLISQHACD -DMFEILAKQQF-RNRIPNLLPENTIVGHKTGTVAS-VVNDAGIVKLPGDGTLIISAFSIG -NK-TEAEGARKIAELSKAAYDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter holothuriorum TaxID=241145 RepID=A0A1T5A680_9FLAO --qQLQKKIAAIFEENQGDFAIAFKNISAEKYNiLINQNENFHAASTMKTPVMIEVFKQAS -EGKFSLKDSLIIRNESIVDGSPFAYEQLGQKRSIKDLVTDMIIYSSNLATNIVIELV-GA -KNVNKTMREIGAMDINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALAKGKAVNPEADK -QMLQILRQQKH-TDLIPALLPKNLKIANKTGWIT-GVHHDSALIELPDGKRYVLVLLSKN -MK-DMEAGTRMLAEVSKMVYDH- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6ADW7_9BACT --kKLETRVDEIANRLDGVMGVAILDLTDGRVL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKARLDDIYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVTVSDNAATNVLIDRV-GK -DNVNAMLHSLGLSKTMLRRKMMDVAAARRG-DENVATPQEMVRLLEAIYKEKVLDKQATA -EFIKQLSTSKQ--SYIPRYLPENVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY -DR-DEKAAGRAISDVALEAYHYf ->[subseq from] Extended spectrum beta-lactamase VEB (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1Q3T5_KLEPN ------------------------------------------PMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -S---------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium periodonticum D10 TaxID=620833 RepID=K1GKV3_9FUSO ---DWKKEIEKIISEVKGQVSVSFYDLGKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAELSLSQKITLTDSMRVGGDGILKVLASGHFSLKELAKLMIVVSDNEATNILIDLL-TM -ENINALGRNLALKETFLQRKMMDSKAK-EKGYDNYTSSDDIALLLRLIYEGKLINEEASE -IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MS--NLECRETIGKISKYIYDK- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0007E365D1 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNK-------------------------------------------------- ------------------------ ->[subseq from] Imipenem-hydrolyzing beta-lactamase n=1 Tax=bacterium HR10 TaxID=2035405 RepID=A0A2H5VXC0_9BACT --eKTEARLREIVASARGVMGIVVVDLVSGERF-AINEDLVFPQGSAIKIPILMEVYKQAH -EGRFRLTDRRRLEKAHVVGGSGILKEFGEGLLSIYDLCVLMIVLSDNTATNMLIEMV-GM -ENVNRTMAALGLTRTRLQRKMIDPAAS-ARGEENLSTPAEAARLMEILYRGEFINREVCD -QILAILKKPKR--TAVSAGVPSDVPIASKPGSIP-GVSTEWAIVELRER-PYVIVVMENY -GM--GEEAPAAFREISRTVYDYf ->[subseq from] Beta-lactamase (Fragment) n=3 Tax=Enterobacteriaceae TaxID=543 RepID=A0A140DR55_ECOLX ------------------------------------------------------------- ----------------------------------VGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYLR- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. BT328 TaxID=2692134 RepID=UPI0014100FC6 ---------TAYIHRLNARISIATKSLADSSLSfYERADERVPSASVIKLPIMIEAMERVK -AGTLDLDEIHILTDSEKTGGDGVLKTYSHRSVSYRDMLRLMMVFSDNTATNIFINEL-GR -DAINQRIRQLGLTKSQLNRVMMDTLAA-RQGRDNYVTAREMGQLLEKIYRKQVATPELCD -QMIDILKQNED-TKTIPSLLPKGTVVAHKTGTLTN-VRGDVGVVYAKSGKPFLLSIFVEG -IA--QPEAERIIGEVAFICYSYy ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Tolypothrix sp. NIES-4075 TaxID=2005459 RepID=A0A218QND1_9CYAN ----LNSQIKALMNRYTLSPGMFFLDLQTGNYV-DINGEKIFSAASTIKFPVLVALFQEID -AGRIKLDEKLVMRRGLIAGESGTMQKPVNTKFSVLQTLTNMIVISDNTATNMIIDRLGGE -TKLNQRFRNWGLQNTVIRNNLPDVGGT------NTTSPKDLVRLSALLSNNRLLSPQSHN -QVLAIMRQTHN-RSLLPAGIDKKAIISHKTGTLRF-VLGDAGIIQMPNGKSYLAGILVHR -PNYD-DGAVSFIRQVSRAVYNY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5US37_9BACT --kKLETRVEEIAARLDGVMGVAILDLTDGRIL-LRNADRFFPTASSIKIAILLELYRQDQ -KGKAKLDDIYIFDPKDLFEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAATNVLIDRV-GM -QNVNATMRSLGLTKTMLRRKMIDVAAARRG-DENVSTPQEMVRLFEMIYKGKALNKELTD -ELIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GVRNDTGIVFAHNR-PFAISVMTAY -DR-DEKAAERAISGVALEAYHYf ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma endophyticum TaxID=662367 RepID=A0A1I1X695_9BACT --dQLTQKINAELAKQPGTFAVAFRDLTTGKEL-LIRERETFHAASTMKTPVMIEVYKQVA -QHKMALADSITITTESIVDGSPYSYKAVGTKRTLAALVYDMIIVSSNLATNLVIERV-GA -QNVTKTMRDLGTKDIQVRRGVED-NKAFAQGLNNTTTAYDLMVIFDRIATGKAVSPEASK -AMIATLLDQKF-NTAIPAKLPKDVKVAHKTGSVT-GVRHDSGIVFLPDGRKYVLILLSKD -IK-DDNATLGVMATLSEWIYQY- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium TaxID=2498093 RepID=A0A4S4H4G5_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLVLTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKNRMTIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf17 TaxID=1735683 RepID=A0A0Q4FL37_9SPHN ------NAVQALGSSFQGQVGIAVRDVTDGWVV-GYNADAAMPQQSVSKLWVAIAVMDAVD -RGALSLSDAVTVRQSDLTVHQPIRARVGADGTTVSALLDCAMTRSDNTCNDVLLWKVGGP -TAIRRMLTAKRIAGVSFGPGERVLQARYLAAPYDGASANGITLGLALLQRGELLSNASTV -HLLTVMGASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLRSPDGHTYAIAVLIGS -TRRPIPARMQFMGNVTRAVIQ-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. ZYM-1 TaxID=1681184 RepID=A0A0P7N290_9BACI -----EKMIQDMIQETPYKVHLFVKNPKTEQFLyRYQMEESFSSASVIKVPILLAVLAYIE -KHSLSLHSSLSISPDDWVDYSVVSEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM -EYLNDYFRQIGLQETLLQRKMMDVDR-LAKGIDNFTSPRDMAHLFTRIYQQDLVSSPYSE -LAIDILSRQRV-SDGLKRYLVDDVKLAHKTGGLET-VNHDVGIVYSSAVD-YIIGIFVTN -VT-DNNQARQLIGRLSKVVYAH- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Blastopirellula retiformator TaxID=2527970 RepID=A0A5C5UWF4_9BACT ---DLAEALLPALKRHRGEAAVVIKHLPSGATF-AFHGDRPQSTASLIKLPLLMALYQAVN -EKQVTLDALVEMKKEDQVPGSGILTGHFSPGLSVRDAAHLMVTYSDNTATNLVIDQV-GL -PATRKLMKTLDCPSTQLNSKVFRRDTSSKQYGLGVTSCDDMIRLLELLHKGEFIDKATSQ -AIIDQLAFVND-KSKVTRFLPPGVKPAHKTGAVND-ARTDAGIIPLPEGA-LLFCVLTQQ -NEGDKNEAELLAAEIGQVAYHYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Blastopirellula retiformator TaxID=2527970 RepID=A0A5C5UWF4_9BACT ----------------------TVIDLDSGKTLgGDNADGVRDPASVTKIMTAYLVLQMAE -ESPELLDEIVTFSQRADKTPGSTSGLKVGEQVSVGELLYGLMLPSGNDASVALAEHFGDV -AAMNSQAEKLGMTQTGYANPHGL------TAKGHVTTAADMAKLGRAAMQLERFREIVAT -PQRGATVESKTGYQRTNRLLHQEGYFGVKTGTTGQAGACLVSCCERDGK----------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Emticicia oligotrophica TaxID=312279 RepID=UPI00025F57BC ---ATKTAIEAKLKAVDGVFAVAFKDLQTGKTL-FINEKENFHAASTMKTPVMIEVFKQAK -AGKFKLTDSILVKNESIVDGSPYSYKQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KNANQSMRALGAKDIQVLRGVEDQK-AFDKGLSNTTTAYDLMLIFEKIAENKVIDKKSCE -EMRKILFDQKF-NEIIPEKLPKTVKVAHKTGSIT-GVQHDSGIVYLPDGRKYVLVLLSKK -LK-NADAGVKVLAEVSEMIYE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides caecimuris TaxID=1796613 RepID=A0A1C7H504_9BACE --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKNRITIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQSYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIITEVSKIVLE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf23 TaxID=1735689 RepID=UPI0009E93EE0 ---DLLNAVQALGAGFEGQVGISVRDIDENWVV-DWQGDIPRPQQSVSKLWVAIGVMDTID -RKRMSLVDPVTVTRADLTVHQPIRTVVGKAGTTVGDLLRGAMTRSDNTANDVLLWRIGGP -AAVNRMLKDKRVAGVRFGPGERQLQARYLEAPLDGASANGVTLGLSLLAQGRLLSDRSTT -SLLTLMRASKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPARMRLMGDVTRAVIA-- ->[subseq from] serine hydrolase n=1 Tax=Nostoc sp. UIC 10630 TaxID=2100146 RepID=UPI0013D6FDD5 ---ELKTPIKALMARYRLTPGIFFMDLKTGDYF-SFNGGKAFSAASTIKYPILIALFQEVD -AGRIKLGETLVMRRKHVTGGSGNLQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV -SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISDRSQS -QVLGIMIRCQN-RKLLPSGLGSGANIAHKTGTLRF-ILGDAGIIETPSGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HPT9_9BACT --eKLDARAGEMVERFEGVMGVAIVDLTDGRAI-LQNADRVFPTASSIKIAILLELYRQEQ -QGKAKLDDVYTFDPKDLVEDSQIMAGLTAGVVTNRDLAQFMIAVSDNAATNVLIDRV-GM -QNVNAMLRNFGLTKTMLRRKMMDIAAAKRG-DENVSTPQEMARLLETIHKGKALSTELTA -GFIKQLKTLKK-DSYLSYELPPGVEIADKPGSLD-GVRTDSGIIFAKNR-PFAISVMTAY -DR-DERAAEHAISEVALEAFRYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A2D6UQS7_9SPHN --rELDQAVSRIGGTFXGHVGIAVRDXEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLXLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAXTESDNTANDRLLRRVGGA -XXVQDFLDTHGLASIRFGXDERSKQSSYLADPIDGAPPVALVEALARXQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Beta-lactamase n=1 Tax=Stigmatella aurantiaca (strain DW4/3-1) TaxID=378806 RepID=E3FNK7_STIAD ------ELLQQISQVKGGTVAVAYRDLGDSRDAvFLEADTSFHAASTMKVPVMIEFFRQVD -AGVLALDQPIVLTNRSIVDGSPYSYEHLGRPMPASELLKRMITRSSNLATNSLIALV-GA -KRVTRTLRTLGAPSMTVLRGVEDGK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ -AMRDILLAQEL-NALIPAGLPPGTPVAHKTGQIT-AVLHDAAIVYPAGRAPYVLVVLTRG -IA-DEQVARALIVDLSRSVHA-- ->[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A326GFP8_9SPHN -hqALQSELVAIDGAFAGDAGIAVVEVASGAVM-QSDGRVPFPQQSVSKLWVAMTALDLVD -KGKLGLQEPVSIGRQDLTLHQPIRAIVLEHGTNFGELLHRAITESDNTANDRLLLRVGGP -QAVEGYLRRQSISGVQFGTDERTKQSAYLADPIDGASATGMATALARLARGELLSGPSTR -LLLGTMAQTKSGPNRLKGSVPEGWSMAHKTGTGQQSGYNDVGILTAPDGTQFAIAVLIGS -TRSSYAERFAMMQAVTSAVVRY- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:487 TaxID=1262928 RepID=R5PW78_9BACT ---SLAERIDSILSGRRMTVGVSAEC-GDFSYV--RNARVRFPLMSVFKVHVAMKVLADMS -ASGTSLDTVVHVERAMLREYSPLRDARPSGDITLAGLMRYSVAESDNNACDILIRMAGGI -GQVDRYVRSLGVDGFRLMHDEDAMHRDITRCYDNWSTPEAMTRLMKIIFEGSA---PLYA -PLRSMMAAIVTGADKIRAGVPESLPVAHKTGSSDKTGDNDVAVVRMPSGRNCYITVFIKD -SAETDAVNAAVIAAVAREIVE-- ->[subseq from] serine hydrolase n=1 Tax=Paucisalibacillus globulus TaxID=351095 RepID=UPI000A00D08D ---NLTERIRRIMEAAGGTWGISLHDLDTNETW-EFNAHELFYSASVIKIPIMIAVFAASH -RKEISLSNCLPLKREDMVGGSGVLQHMTPGTITIYDLITLMIIQSDNTATNILIDLV-GT -EAIQQSLKEMGLEKSKFYHKMMTQDAN--REGLNEITAHEMTNMLKELATGKIISVHACE -QMIDRMKKQQV-RNSLPANIPKQWEIANKTGNIS-GVRHDVGIFYVGKR-TLIASILSRG -VD-D-LKSAA------------- ->[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. ZZJ9 TaxID=2315727 RepID=A0A368JSE3_9BACT ---------------AQAQVNVAFESLVDGTQF-VHRPDELAPSASVIKIPIMIETMEQVK -AGKFDLDKIHVLLASEKTGGSGVLQTYPDESITNLEVLTLMMTRSDNSATNILIREL-GM -DNINRRMQTLGLTQSRLNRVMMDTLAA-KQGRENRVTAREMNLLLKKIYRNEVATPALCA -QMIDILKRNAD-QTTFRLFLPKSAVIAHKTGELTY-VRGDAGIFYVT--KPFLLSIFVQG -TT--TPEAEKIIGEIAAICYNQy ->[subseq from] serine hydrolase n=1 Tax=Clostridium peptidivorans TaxID=100174 RepID=UPI000BE3CF99 -----DQKLYSILGTLEGEVGIYFEDIQTGEKI-LINPDSVFSAASTVKIPLVSLLFQEVS -EGKINLNDIIELSEENRVGGTGIIKNLDKRYPTVLDLATLAIIVSDNAATNQLVDLVGGL -EGITKYCDSIGLTNTKFQRKMMDIKAK-ASGKDNLTTARDMGNILAKLARNEIVSANASR -QIVDIMKSQQL-RSKLPAYIPAIVMVANKTGDLDR-VQHDVGIFILPGNNYYILTMFTSN -LSAD-SEGIRAIGEVSKAIYEE- ->[subseq from] Serine hydrolase n=1 Tax=Chamaesiphon polymorphus CCALA 037 TaxID=2107692 RepID=A0A2T1FWF8_9CYAN ----LKSQIKTLAAKYSISPGMFFMEVDTGNYL-DINGEKSFPAASTIKLPILMALFQAVD -SGQVKLDEKLTVRRDLITGGSGELQNSRGAKLSVFQTATKMIAISDNTATNMIIDRLGGR -KVLNSKFKSWGLRKTVINRMLGDFKGA------NTTSPADLVRVSALLAKRQLITETSRS -KVLDILNQTAN-RKLLPAGLGKGAAIAHKTGTLGR-LIGDAGIIEMPNGKLYLAGIFVKR -SFND-VRARNFVQAVSKLTYNY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6JD60_9BACT --kKLELRIDEIAMLFDGVMGIAIVDLTDGRPAlLRNAEHVFPAASSIKLPILLELYHQDE -KGKATLDDLYTVDPKDLVEDSRVMGGLSAGVVTNRDLAQFMVAVSDNTAANVLIDRI-GK -DNVNATLRGLGLTKTMLRRKMMDVTAAQ-RGDENVATPHEMVQLLEAIYKGKVLKADSTK -QLIKQLSTLKP--SYIPRDLPDGVQVANKPGELE-GVRTDSGIVFSANR-PFAISVMTAY -AS-DERAAERAISDVAREAYHYf ->[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. ZZJ9 TaxID=2315727 RepID=A0A368JS31_9BACT --eQLRQQIEAQLAKQPGRFAVAFKDLTTGQEL-LIHEREEFHAASTMKTPVMIEVYKQAT -QKRFSLSDSILIKNESIVDGSPYSYTKVGTKLPLSAVMYDMIILSSNLATNLIIERV-DA -KKVMQTMREMGAKDMQVRRGVEDTKA-FQQGLNNTTTAYDLMVLFEKIATGKAVSPEASQ -DMIRILLDQRF-NSVIPAKLPKNVKVAHKTGSITS-VRHDSGIVFLPDGRQYVLVLLSKE -IKSD-AAVIESLATVSGMIYQYf ->[subseq from] Beta-lactamase class A n=1 Tax=Allonocardiopsis opalescens TaxID=1144618 RepID=A0A2T0QA86_9ACTN ----------------------------------AHRPDQVMPTCSVFKSFLVAALLHDRD -DREYWYDAAIDYDESDVVINSAVLSERSG-PISPHDLAEAALRYSDNTAANLLLAELGGP -AVLTEFTRSLGAAVTRFDRLEPELNAAVPGDDRDTSTPAEVAMLMHAVLVERSAGAYTAA -RLNTWMLWNET--SRITEALRTGDELTDRTGAGAYGVVNDAGVLYRPGQPPRSFAVMTRT -DDEDAENDDAVVLEAARLL---- ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127STV8_9BACT --------------------------------V-SVNNMYRYPMMSTYKFHQALSVVDYLH -KHDKNLATEILVKKSDLLAHSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP -LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL -FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN -SRETDQENAKIMADISRTVYEYf ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SQ09_9BACT --kTIEKALLEYVSDKDARIGIAVI-VNGTDTI-SINGKRYFPMMSVVKFPLALTVVQWID -ANGLSLNDSIAFSEKALKEYSPMLKRYGKKRMTVRELLEWSLVESDNNAADILLNHVGGI -SGATKIMRKIGVDNIEIGASEDDMHRDPYLSYLNRTTPLAMAQLFNRFDAEMRNTSLSYS -EIATMLEQCRTGIDRLVALLSSDATIGHKTGTGFISAINDCGYVNLPNGVRYSIAVFVAD -SGYDMAGTSAIIAEISRIVW--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. ABOLE TaxID=1985878 RepID=A0A430EL96_9SPHN ---ALLNAVQALGAGFHGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HARMTLATPVTVTRSDLTVHQPIRPLVGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP -TAIRRMLKEKGVDGVGFGPGERELQARYLAAPYDGATANGVTLGLSLLAQGKLLGRTSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGDVTRAVIR-- ->[subseq from] serine hydrolase n=1 Tax=Citromicrobium sp. JLT1363 TaxID=517722 RepID=UPI000225EB75 ----FERQIATLADGSNGRIGVYAIDLATGEEV-GILADQRFPMASTSKVAIAATFLAGVD -QGRWSLTSEFELPG-------------RGTYISGREHLDLMISRSCNDCTDALLNAVGGP -QAVNAWMRQAGIYDFELTRDIATLVRASEIAFEDSATPRAMGRLLAGIYQGKWLSSYSRQ -VLMNAMASTVTGKRRMTSALPDSANLAHKTGTLSR-TASDIGIFYTPDGRPVAAAIYVTG -QSVSMASEN-------------- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000B9595A2 ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Gloeobacter kilaueensis JS1 TaxID=1183438 RepID=U5QHF3_9CYAN ---ALEAAMHKLTQQPRLRSGFLFFDPATGAYA-QMAADESFSAASVIKVPVLVELMRQVD -GGSVRLDEVLTLKAAHKGGGSGWLQYRPNGTMSVLAVATLMIIRSDNTATNMIIDRLGGA -AYLNEQFRRWGLRRTVINAPLPDLEGT------NTTSPGDLALLMSELDRGELTSPQGRT -VAYGLMGRTRI-GSLLPMGLGPGARILHKTGDIGK-MVGDVGVVTTPDGRRYLATALVER -PHND-RRANQLIAKLSQAFYHVf ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235IQQ0_9NOSO ---ELKTPIKALMARYRLTPGIFFMDLQTGDYF-SFNGDKAFSAASTIKYPILIALFQEVD -AGRIKLGETLIMRRKHVAGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGA -SKLNQKFRTWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISDTSQS -QVLGIMIRCHN-KSLLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. EC-SD391 TaxID=2038398 RepID=A0A5E7YBE9_9SPHN ---DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTQSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRKPIPARMRLMGDLTRAVVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax cattleyae TaxID=80868 RepID=A0A1H0V480_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQAVARALDLKTSELQATMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQEGARAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFI8_9BACT ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAEVSAAALQYSDNTAMNKLIAQLGGP -GGVTAFAREIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSW------------------------------------ ------------------------ ->[subseq from] Penicillin-binding protein, transpeptidase n=1 Tax=Calothrix sp. PCC 6303 TaxID=1170562 RepID=K9V0Y7_9CYAN ----VSSQVKSLMNRYSLDPGIFFLDLQTGNYI-DFNGEKAFPAASTIKFPILIALFQEID -AGRIKLNETLVMRRNLITGGSGNFQYKPAGSFSLLETATKMITISDNTATNMIIDRLGGK -AKLNPKFRAWGLQNTVIRNLLGDFKGT------NTSSPKDLVRLSALIANNQLLNDRSRN -RVLDIMRRVEN-QSLLVSGLGKGTIIAHKTGTLGI-VLGDAGIVQTPSGKRYLAGIMVRR -PFGD-SRAKSFITQVSRLVYG-- ->[subseq from] Uncharacterized protein n=3 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A1G1Q060_9BACT ------------IADFRGNIGIVIKDLNEGWEI-DFNKGALFPSASLVKVPILLSYFYAQQ -EGKVRTSDLVSLKSYEKVPGSKVLGDSSVGSFSVEELFEPMIAKSDNTATNILIDLL-GF -EAFNDYFIRLGLRNTNLVRRMMDFEER-KEGRENYTTAEDMAYLLEILYRRSFLDKNTSE -KCLGFLKQQKI-KDRIPRKLPEGVTVAHKTGLENY-ICHDAGIVFTQKGD-FLICVLTKH -QDKFAAPAKRFISDIALITYNYy ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000A100C18 ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KTIKKRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. animalis TaxID=76859 RepID=A0A2G9FA65_FUSNU --tEWKKEIEKIISRVKGSVCINFYDLAKNNGF-SINGDKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM -KNINQLGREVDLKETFLGRKMMDIEAR-KKGYDNYTCADDISSLLKLIYQEKLINEEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGNKA-YILVVLTSG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KF98_9BACT -------AIREIVRPLKAHVGVSAVMLDTGESV-SVGDEAFYPMQSVYKFPLALSVLKRVD -QGVLDLDQKVKVTRDQLPEWSPLRDRFPQGGFPLKELLRFSVQESDNNACDILFSLIGGP -ANVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPTAMTSLFRMFDEGKILKKDTQL -FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGT------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI001412FCA0 --eQLRKEIESRFKSVEGDFGLAFKDLQTGATL-LIREKETFHAASTMKTPVMIEVYKQAG -EGKFKLTDSIVVKNESIVDGSPFSYKKIGQKMTIYDLTYQMIIVSSNLATNILIDLV-DA -RKANETMRKMGAKDIQVLRGVEDDK-AFQLKMNNTTTAYDLMLIFEQIALKKAVSKRSSE -EMIKVLSDQKF-NEIIPARLPAGVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKN -LK-DKDKGVAMLADVSALLYD-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobium limneticum TaxID=1007511 RepID=A0A5J5HSQ7_9SPHN ------NTIQALGAGFNGQVGISVRDIDEGWVA-AWEGDIPRPQQSVSKLWVAIGVMDAVD -RQRLSLTDPVTVTRADLTVHQPIRTLVGKTGTTIADLLHGAMARSDNTASDVLLWRIGGP -AIINRLLGDKGIGGVRFGPGERQLQARYLAAPLDGASANGVTLGLSLLAQGKLLSPQSTA -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYALAVMIAS -TRQPIPVRMRLMGNVTRAVIA-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649UH73_PSEAI ----FKTDLEKLESEKAAQIGVAIVDPQGEIVA-GHRMAQRFAMCSTFKFPLAALVFERID -SGTERGDRKLSYGPDMIVGWSPATERFLASGMTVLEAAQAAVQLSDNGATNLLLREIGGP -AAMTQYFRKIGDSVSRLDRKEPEMSDNTPGDLRDTTTPIAMAGTVAKVLYGGALTSTSTH -TIERW------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Aquincola tertiaricarbonis TaxID=391953 RepID=UPI000614A0C0 ---RLQAELAQVAQRHSARIGVYVRDLDSGASA-SFQADRPWYLASTVKVPVAIAVLRGVE -RGDFGLDTPLTLRAADLVDGAGPTRKPLGAPLTVRYLLEQMIVWSDNTASDMLIGLV-GI -QAVNALVQELVPGGFERITSLADVRRAYYATGLNTGRLDAYGELLARLVEGQALGPKGTA -WLLRLMERVKTGPNRIKAGLPTRARFAHKTGTQR-GRTCDAGVISVPGKDSRVLVAACTS -GELSVARSDRALREVGAAIC--- ->[subseq from] serine hydrolase n=1 Tax=Gloeobacter violaceus TaxID=33072 RepID=UPI00030E8212 ---SLESAMLKLTDQPRLRSGFMFVEPASGRYV-AMADGESFSAASVIKVPVLVEFLRQVD -SGRLKLDDTLILRQEHKGGGSGWMQYMPNGKMSAYNVARLMIVRSDNTATNMIIDLVGGA -DYLNAQFGRWGLRTTRINAPLPDLEGT------NTTSPADMALLLTELERGRLVTTQMRA -KGYELMGRTRT-GSLLPVGLGPGAKILHKTGDIGK-MVGDAAVVTMPDGRRYVAVALVER -PHND-RRANQLIAKLSQKFYYV- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFH2_9BACT ------------------------------------------------------------- ------LNQRVEIKKSELVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWV----------------------------------- ------------------------ ->[subseq from] Extended spectrum beta-lactamase VEB (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A1U9YG06_KLEPN ------------------------------------------PMQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -S---------------------- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax cattleyae TaxID=80868 RepID=UPI000B88F911 ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQAVARALDLKTSELQATMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQEGARAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Citromicrobium TaxID=2630544 RepID=A0A0P7A0T1_9SPHN ----LDDQLFALGTGLKGKVGIAVYDPARGRMM-HFKGTQLYPQQSVSKLWVALSALDMAD -AGRLDLSETATVRNGDLAVHSPIRQSVAAQGTSYADFISRALTQSDNTANDMVLRRVGGS -DAVRRVLARKGFADIRFGPGERPMQSAYVDDPVDGASPVAIASALARLESGELLSDASTT -RFLGWLGEVKSGPNRLKGGLPDGWSIAHKTGTGQQAGYNDVGILTAPDGSVYTVAVMIGR -TQVPIPVRMEMMHGVVRAVAG-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter sp. SW132 TaxID=2293433 RepID=A0A371QTQ1_9BACT ------------------------------------------------------------- --------------------------------------------------------RLRGI -SNMSERLDEL-VRIMDVDRDELNAENKYYDGGLNSGTMEAMSVMLERLVEGEYLNEENTD -LLIEIMEVIATGDHRIKAGLPEGIRFAQKTGTLI-GRACNVGVIYPQDQKPIVVSVCAKD -YN-QLSDAENAFQRIGMVISENw ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroides sp. TaxID=29523 RepID=A0A351YGJ7_9BACE ----LQDDVEDYLEDKQATVGISVL-TDTCTIL-AVNDTTRLPLLSVFKFPVAWAVLHRIE -RHGTPLDTVFHLTPDDLKTYSPLCMSHPDRTVRMDSLLFYSVALSDNNACDVLLKYAGGP -KAVERYIHDLGIADISLSATEDDMHREPSKALDNNATARAVSQMFQRFMQRDTLGTAHHN -FLFRTLTATSTGNNKLRAGIPRHQMFGHKTGSSDRTADNDAGFVVMPNGQRYYITVLVNN -SMENDSVNAAIISTVSQMTYD-- ->[subseq from] Serine hydrolase n=2 Tax=Sphingomonas TaxID=13687 RepID=A0A0W1QM95_9SPHN -----VNRLADLAHGFEGVVGIAVTSVDRNWTA-SQGGARKLPQQSVSKLWVAMTVLDQVD -QGRIRLEDPLVITRADFTLHQPVASLVKGDQSTVGEILRRALTMSDNTCNDKLLRLVGGP -PAVRSFIARNALGPIRFGPGEKLLQLSYVADPPDGAAPLAIAGALARLKRGELLSPVSTQ -WLIATMQASHTGKYRLRGALPPGWQLAHKTGTGQTAGYNDVALLTAPDGRSYALAVMIGD -TPRPINERQLLMQGVVRAIVA-- ->[subseq from] Serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=A0A1U7LZN2_9FIRM --nKLKDEVKNIINESFFNVSISFCDLDNGEHF-SVEGDKRMQSASMIKLLIMLTLLKKVE -EGEISLDEKIKLEKEKRVEGSGILKELSYDHFSIRELLTLMIIISDNFATNILIGKI-GM -DEINRTAKDFGLKKTILQRNMMDLDAK-ERGLDNYTSSDDILKILKSIYEKNFLGEDMSK -LAIDILLKQQE-RDRLQRYLKEDLKIANKTGDLDN-LENDGGIFFTENK-NYILVVLVNQ -AKS-NILAKELIGKISLKIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MDE8_9BACL ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNVMQKTKMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRHLATGKVISYDSCL -KMVAILKAQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHGy ->[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus sp. OK032 TaxID=1884358 RepID=A0A1H9X2R0_9BACI --kALSNKINDLIGQSKGTWGIVLEDLDVGEKW-ALNENELFYAASVIKVPLMVAVFSAVE -RGEIALTDQIILKEEDIVGGSGVLQHLTQETFSLQDMIMLMIIQSDNTATNILIDQV-GV -EHIVQTMKEVGMDKSTFYNKLM-MNRPNPK-GFNRITASEIAKLLKLMATGELVSADASK -QMLDIMKKQQI-KDCLPAKLPTAWELAHKTGWIP-GTRHDVGIFYVGQRK-LIATVLSKG -VD--DLVSKRVLADTGEVIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6CCB7_9BACT --kKLEARVDEIAERFDGVMGVAIVDLMDDRAI-LKNADHVFPTASSIKIAILLELYRQEQ -QGKAKLDDIYTFEAKNLVDGSQIMTGLTPGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM -QNVNATLRNLGLTKTMLRRKMMDIAAARRG-DENVSTPQEMMRLLEAIYQGKALDKELAK -AFMKQLSTKKE--SYIPRQLPPDVSIANKPGDLD-GVRTDSGIVFAKNR-PFAISVMTTY -DRE-ERAAESAIAEIALEAFHYf ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium pseudoperiodonticum TaxID=2663009 RepID=A0A2D3PPH5_9FUSO --tEWKKEIEKIISEVKGQVSVSFYDLDKNIAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAKLSLSQKIILTDSMRVGGDGILKVLDSGHFSLKELAKLMIVVSDNEATNILIDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLRLIYEGKLINEETSE -IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -MS--NLECRETIGKISKYIYDK- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1W6RZ34_9BACT ------------------------------------------------------------- -------------------------------------------------AMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPK------------------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=A0A0Q4JQP8_9SPHN ---DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRKPIPARMRLMGDLTRAVVA-- ->[subseq from] Uncharacterized protein n=1 Tax=Geosporobacter ferrireducens TaxID=1424294 RepID=A0A1D8GP08_9CLOT ----LEKEIIRALESTSAKTSVVLKDLRNDIWIfQKEEKMVIPSASTIKILIMTEALNQIQ -QGKYQLEEKVSIMEEEKVPYSIISDL-TTDFYTFQDLITLMIIVSDNTATNVLIDLL-GF -DAINEMATKIGLKNTQLKRKMMDFEAA-QMGRQNITTAIDMAMLMEKIFNREILNEKLCN -HAIDILKRQKD-KIMLKRYIPEDTVIAHKTGDLAN-LNHDIGIFYLPQQT-YLLGVFVTE -AQ-SNLAAQQIIGEISKLVYTYy ->[subseq from] AMIN domain-containing protein n=1 Tax=Calothrix sp. PCC 7103 TaxID=32057 RepID=UPI0003734E22 ---QLSSQVRSLMSRYSLDPGLFFIDLETGNYV-DYNGEKAFSAASTIKFPILIALFQEID -AGRVKLNETLTMRRDLVTGGSGTMQYRAPGTFSLLETATKMITISDNTATNMIIDRLGGR -NKLNPRFRTWGLQNTVIRNLLGDFKGT------NITSAKDLVRLSALVANNQLLSNSSRV -RVLDIMRRVEN-TSLLASGLGRGATIAHKTGTLGV-ILGDAGIIQMPNGKRYLAGIFVRR -PFGD-ARGREFISQVSRTVYS-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E8958 ---------TAYIHRLNARISIATKSLADSSLSfYERADERVPSASVIKLPIMIEAMERVK -AGTLDLDEIHILTDSEKTGGDGVLKTYSHRSVSYRDMLRLMMVFSDNTATNIFINEL-GR -DAINQRIHQLGLAQSQLNRVMMDTLAA-RQGRDNYVTAREMSQLLEKIYRKQVATPELCD -QMIDILKQNED-TKTIPGLLPKGTVVAHKTGTLTY-VRGDVGIVYAKSGQPFLLSVFVEG -VA--QPEAERIIGEIALICYTYy ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6BYB5_9BACT --kKLEARVDEIAQRFDGVMGIAIVDLTDERAI-LKNADQVFPTASSIKIAILLELYRQEQ -QGKAKLDDTYTFDAKDVVDGSQIMTGLTSGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM -QNVNATLRNLGLTKTTLRRKMMDIAAA-KRGEENVSTPQEMTRLLEAIHKGKALDKELAN -AFMKQLSTKKE--SYIPRRLPPDVDVANKPGDLD-GVRTDSGIVFAKNR-PFAISVMTAY -DR-DERAAEGAIAEIALEAFHYf ->[subseq from] Beta-lactamase n=1 Tax=Rhodobacterales bacterium 12-64-8 TaxID=1970554 RepID=A0A257Y7R8_9RHOB -----VERFRAIADYVAGRLGVCAIDTGNGRTL-GTNTNGRFAMASTFKWLLAAAVLKRHE -AIPTILDQTRRVEEKNLLDYAPVTS-VIAGKLSLAELCSAAVSVSDNTAANLLLSHLGGP -AALTQFLRESGDTVTRLDRTEPTLNENAKGDPRDTTTPAEMAQTMARLLTDEVLNAASRA -RLIGWMRASTTGTACVRACLRSGM------------------------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Citromicrobium TaxID=72173 RepID=UPI000C1B9BA3 ----LDDQLFALGTGLKGKVGIAVYDPARGRMM-HFKGTQLYPQQSVSKLWVALSALDMAD -AGRLDLSETATVRNGDLAVHSPIRQSVAAQGTSYADFISRALTQSDNTANDMVLRRVGGS -DAVRRVLARKGFADIRFGPGERPMQSAYVDDPVDGASPVAIASALARLESGELLSDASTT -RFLGWLGEVKSGPNRLKGGLPDGWSIAHKTGTGQQAGYNDVGILTAPDGSVYTVAVMIGR -TQVPIPVRMEMMHGVVRAVAG-- ->[subseq from] Beta-lactamase n=1 Tax=Nostoc punctiforme (strain ATCC 29133 / PCC 73102) TaxID=63737 RepID=B2J9P6_NOSP7 ---ELKTPIKALMARYRLTPGIFFMDLKTGDYF-SFNGDKAFSAASTIKYPILIALFQEID -AGKIKLGEALVMRRKHVTGGSGDLQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV -SKLNQKFRRWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTKNQLISDRSQS -QVLGIMIRCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPTGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A0_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKHLNEGTTIGELAAAALQYSDNTAMNKLIEHLGGP -NKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRTGLPATWIV---------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFI7_9BACT ------------------------------------------------------------- ------LNQPVEIMPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWT----------------------------------- ------------------------ ->[subseq from] Imipenem-hydrolyzing beta-lactamase n=1 Tax=bacterium HR08 TaxID=2035403 RepID=A0A2H5VMZ6_9BACT --eKTEARLREIVASARGVMGVVVVDLVSGERF-AINEDLVFPQGSAIKIPILMEVYKQAH -EGRFRLTDRRRLEKAHVVGGSGILKEFGEGMLSIYDLCVLMIVLSDNTATNMLIDLV-GM -ENVNRTMASLGLARTRLQRKMIDPAAS-ARGEENLSTPAEAARLMEILYRGEFINREVCD -QILAVLKKPKR--TAVSAGVPSGVPIASKPGSIP-GVSTEWAIVDLRER-PYIIVVMETY -GMG--EDTPATFREISQTVYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFH1_9BACT ------------------------------------------------------------- ------LNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAVLPASWV----------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Gloeobacter kilaueensis TaxID=1416614 RepID=UPI001182E98C ---ALEAAMHKLTQQPRLRSGFLFFDPATGAYA-QMAADESFSAASVIKVPVLVELMRQVD -GGSVRLDEVLTLKAAHKGGGSGWLQYRPNGTMSVLAVATLMIIRSDNTATNMIIDRLGGA -AYLNEQFRRWGLRRTVINAPLPDLEGT------NTTSPGDLALLMSELDRGELTSPQGRT -VAYGLMGRTRI-GSLLPMGLGPGARILHKTGDIGK-MVGDVGVVTTPDGRRYLATALVER -PHND-RRANQLIAKLSQAFYHVf ->[subseq from] ClassA (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SAX3_9BACT ------------------------------------------------------------- --ENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATDQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Serine hydrolase n=1 Tax=Citromicrobium sp. TaxID=2024827 RepID=A0A2E2NIX0_9SPHN ----LDDQLFALGTGLKGKVGIAVYDPARGRMM-HFKGTQLYPQQSVSKLWVALSALDMAD -AGRLDLSETATVRNGDLAVHSPIRQSVAAQGTSYADFISRALTQSDNTANDMVLRRVGGS -DAVRRVLARKGFADIRFGPGERLMQSAYVDDPVDGASPVAIASALARLESGELLSDTSTA -RFLGWLGEVRSGPNRLKGGLPEGWSIAHKTGTGQQAGYNDVGILTAPDGSVYTVAVMIGR -TQVPIPVRMDMMHGVVRAVAG-- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / CIP 101130 / JCM 8532 / LMG 13131) TaxID=190304 RepID=Q8RIK5_FUSNN --tEWKKEIEKIISQVDGKICINFYDLDKKNGF-SINGNEKVLSASMIKLLILAELMKKVS -ENKFSLSDTITITNFMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINFLGKELGLRETFLERRMMDAEA-SKNGYDNYTSADDISLLLKLIYQEKLINKETSQ -LMLDILLRQQQ-GERLQRYLPPDIKIAHKCGDLDN-LENDGGIIWLGNK-IYILVVLTSG -MS--NLQCRQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Scytonema hofmannii PCC 7110 TaxID=128403 RepID=A0A139XFB0_9CYAN ----LYPQVKKLMSRYSLAPGMFFLDLETGNYL-DIYGEKVFPAASTIKYPILIALFQDID -AGKVKLNDTLVLRRNLKAEGSGVLQFKPAGTLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSVMIDNDKLLSPTSRS -KALSIMRRVQN-RRLLPSGLGKGATIAHKTGTLGI-ILGDAGIVELPTGKRYLAGIFVKR -PFGD-TRAREFISQVSKLVYG-- ->[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium RBG_13_44_8b TaxID=1801836 RepID=A0A1G1MM88_9BACT --qELQQRIKAEISQFKGEAGIVIEDLEAGWEF-SYDKAKLFPSASLAKIPLMAACFLAAD -QGRIKLERNIALKSSDKLTGSGVLKDMPAGTFSVERLIGLMIYDSDNTATNIVTNLA-GI -DYLNSAFKSFGLKNTDLSRKIADYQSR-DKGIENYTTAEDMALLLDKIYRRSLGNKNVSD -QCISMLKLTRM-NDRIPKYLPVAITIAHKTGLEK-GVCHDAGIVFTNKGD-LIIVVLTKH -ANPNSVPSKAFIAKVSLHAYKY- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sordidisoli TaxID=2502893 RepID=A0A4Q2UJY6_9BACT ---------------ASARVSVAVESLADSSVSfAHRADERVPSASVIKLPILLEAMERVK -AGTLDLDEIHILTDAEKVGGDGVLKTYSHRSIAYRDLLRLMMVYSDNTATNIFINEL-GM -DAINARIRAVGLPRSQLNRVMMDTLAA-RQGRDNYVTCLEMNRLLKKIYHRQVATPELCE -QMLTLLKQNED-TLTIPRLLPPGTVVAHKTGTLSY-VRADVGIVYA--HQPFLLSIFVEG -LP--TAEAERTIAETARICFTYf ->[subseq from] hypothetical protein n=1 Tax=Spirulina subsalsa TaxID=54311 RepID=UPI0002FE7361 ----LKNRLQSLIARYEFEAGVFFMDLDTGDYV-DIQGSKPFAAASTIKTPILIAFFQALD -AGSVSLTETLVMEEDTRAGEAGDMQQPIGTRFSALDTVTRMITISDNTATNMIMKRLGGQ -DILNQRFAEWGLSATVIRNLLPDLEGT------NTTSAVDLAHVMARVNRGDLVNLRSRD -RLLEIMRNVQN-NQLLPQGLENGAIIAHKTGNIGS-VVADAGLIDTPTGRRYLAAVIIQR -PHND-PKAKDLIRDISREAYQYf ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. EC-SD391 TaxID=2038398 RepID=UPI00125EB4E6 ------NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTQSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRKPIPARMRLMGDLTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522MX78_9BACT --sQLQTRLDSLASRAPGSVAVAVRDLRTGQVA-GYNAQASLPAASTIKVPVMVEVFKQME -DGTFTLGREVTLQNGDRDDWGDLAAAPSGSHYTVRRLLWLMITQSDNTAANMLIRLV-GR -VHVNETMRALGLDHTALSDYIRSYGDI----RSIRTTASDMAHLMALIAHGELVDEWSCG -EMLEIMAGQQI-NTLLPEPLPSDVLIAHKTGSLHD-TLNDVGVVYLHDA-PYAIAVMTTR -LP-SLDSGRAFIHAVSSLAFK-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYB2_FULL_50_12 TaxID=1797969 RepID=A0A1F9X8N7_9BACT ----------ARAEKFPGEAAIVIKDIQTQQEI-GINVARLFPSASLVKVPIMAAVYQAQE -EGKLRLEDHIILKKKHKVRCSRLYNMRPGRKVVIRDIIERMITESDNTATNMLVDAL-GF -GYLNQKFIEFGLKQTDLRRGVMDLKW-RKAGIENYTTAADMALLLEKIYNGELVSHAASA -EMLEVLKRQKV-NDRIPRLLPDGLVIAHKTGLLND-TVSDVGIVFTKEGD-FIICVLTAD -IK-SFLSAKKFIGSVAACAYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=bacterium TaxID=1869227 RepID=A0A539D5D3_9BACT ------------------------------------------------------------- ----------------DMINHAPVTEQAVGGTLTIQQLMEATVGLSDNPAANILIRELGGL -ERLRAFYRGIGDTDTRVDRLEPEMNRL--DGDKDTITPAQSARNIDRLFVDTPLTAASRT -LLLGWMVATPTGPNRLKAGLPADWRLAHKTGTGGYGPTNDIGLAWPPSGGPLIITAYFHG -ARSTEQQREAAIADATRMAL--- ->[subseq from] class A beta-lactamase n=1 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=UPI001371F84E --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRITIRELIEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS -EISVMLEQCRTGLDRLALLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] class A beta-lactamase n=1 Tax=Granulicella sp. L60 TaxID=1641866 RepID=UPI00131D05EB --qSLQQQIQTIAADAHGKVSVACSLPDSPLNC-DLNPTAHPPMQSVFKLPLALTILHQLE -QGKFSIDQPIRFLPEDRILYSSLQDKYPNANVPLRTLLQLTVSLSDNTAADILLRIAGGP -DVVDKYIASLGITGFHLRDGENALHHSVPLQYRNWFEPRSAVQLLRILSDRSPLTPEHTA -QLLAWMRPATP-TTRLQGDLPAGTIVAHKSGTSDAHATNDIGLITLPDGRQLAIAVFVTD -STADTAIREKVIARIARAAYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA12_FULL_49_49 TaxID=1797954 RepID=A0A1F9VGH8_9BACT ----LMAELQGQAAKFKGDAGILVKDISTGESI-SMNSSKLFPSASLVKLPIMAAVYQAEL -EGRLQLTDKLVLKRSHKVRCSKLYFKRNGTKYEINDLIVRMITESDNTASNMLVEAL-GF -GYINQKFVEFGLKDTDLRRGIMDLKWR-RAGIENYTTVEDMAYLLEKIYNRELVSTAASD -RMMAVLKKQKV-NDRIPRKLPDETIVAHKTGSLRD-TISDCGIVFTQKGD-FIVCVITAD -IK-NYRTAKRFIADIAACAYDK- ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00053A5D14 ---AVQQKLAALEKSSGGRLGVALIDTADNTQV-LYRGDERFPMCSTSKVMAAAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAH-------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Glr2387 protein n=1 Tax=Gloeobacter violaceus (strain ATCC 29082 / PCC 7421) TaxID=251221 RepID=Q7NHZ7_GLOVI ---SLESAMLKLTDQPRLRSGFMFVEPASGRYV-AMADGESFSAASVIKVPVLVEFLRQVD -SGRLKLDDTLILRQEHKGGGSGWMQYMPNGKMSAYNVARLMIVRSDNTATNMIIDLVGGA -DYLNAQFGRWGLRTTRINAPLPDLEGT------NTTSPADMALLLTELERGRLVTTQMRA -KGYELMGRTRT-GSLLPVGLGPGAKILHKTGDIGK-MVGDAAVVTMPDGRRYVAVALVER -PHND-RRANQLIAKLSQKFYYV- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=A0A2T5GGQ1_9SPHN ---DLLNAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGITLGLSLLAQGKLLSARSTT -SLLTLMHSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRKPIPARMRLMGDLTRAVVA-- ->[subseq from] Serine hydrolase n=1 Tax=Solibacillus sp. R5-41 TaxID=2048654 RepID=A0A2D1SVL2_9BACL -----KQQLAQLLDQIPYRVHVIIQDYRTNESLiEKNTQSVFSSASVIKVPILMAVLHHLE -KTNGQLSQVVPITSDNVVDFSVLTEQK-QKTATLHELLLWMIITSDNTATNMCIDFI-GI -ETLNYYFQQIGLKSTSVQRKMMDFERQ-QKGFDNVTTARDMQHLFHQIYAGKLLAHEWNE -VALNILLRQRS-HESLKRYLVDDVKIAHKTGGLDT-VDHDVGIVFTEQVD-YFIGVFLTE -VT-DNEKARQYIGQISKIAYAHf ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10401 TaxID=2678657 RepID=UPI0013D58B7F --eELEADIQAVIAGTAGDFGVAFSLLDGSETQlLINEKEVFHAASTMKTPVMIEIYKQVG -SGQIALDDSILILNESIVDGSSYSYERIGKKATVYELMYQMIIKSSNLATNILIERV-GA -ENVTQTMRELGAADIQVLRGVEDLKA-FDAGLSNTTTALDMMLIMKAIATGEAVGQEESR -QMMDILYDQYY-KDLIPKLLPETVKIAHKTGAIT-GVQHDAAILTLPDGRSYVLVILTKN -LE-DLPAGKEAISAISKLIYD-- ->[subseq from] serine hydrolase n=2 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD9709F --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAANLLLESFGGP -PALTEFVRSFDDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Nibribacter sp. BT10 TaxID=2698458 RepID=UPI001366EB5F ---SLKDRISAELSQQKGTFAVAFKDVQTGEEV-LLQEHENFHAASTMKTPVLVEAYKQIE -AGKFTIDSPIEVKNNSIADSSTFSYQHLGKTLPMSDLLYRMIIKSSNLATNIIIELV-GA -ENVTATMRNLGAQEIQVRRGVEDGK-AYALGLNNTTTAYDLMLLYTHLVQGKAVSPAASQ -AMIKILLDQQY-KDIIPAKLPKDVQVAHKTGWIT-GVRHDSGIVFLPDGRKYVLVLLSKQ -LE-DEPAAISAMAQVSLLVYQH- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus okhensis TaxID=333138 RepID=A0A0B0IEU8_9BACI ----LQGCIDEIIHKSTATYGVSIKHLETSEVA-IVNGDKIFQQASVFKIPILVTLLKQVE -SNHLRLDTRVKIKKGDYVPGSGILQELDYGAVSVKDLALLMIIVSDNLATDKLLQMV-GL -DNVQQHMEMLGLKHTTIKHSCYDLLRFERTKKCSVSTANEMNLLLEKLLNYDLLNETNTN -MMLDILLKQRI-QNRLPLLLPEGTKIAHKTGSLDH-YLNDCGIVFLPNDGTYIISVFSSD -HH-STEGGDQEIGEISKAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium SCN 70-22 TaxID=1660163 RepID=A0A1E4B5U4_9BACT ---SLRERIAARVARHGALAGVYYRDLGSGEEL-AWHADSTFHAASTMKVPVMIAYFRGVD -EGRFGAGQRVTLANRSIVDGSPYAYRRVGEEVAVRELVERMITRSSNLATNVVIELV-GA -ERAQATARSLGASTMMVRRGVEDGLA-FRAGLNNTTTARDLGALFEAIGRGAAASGASTR -AMLEILERQEF-NDEIPAGLPPGTRVAHKTGWIT-GILHDAALVLPEGRPPFVLVVLTKG -IP-DEKVAQRLIADIAGMVWAH- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3D2PAI2_9BACT --qTLAEKIKNKLYNFPGNVGLVIKDLKTGKTI-FYNQDKLFPSASLVKIAIMSACFQAES -EGKINFNDYFRLKSKYKSRGSGILRYSPAGKISLKELVELMITKSDNTATNILTEIL-SF -DYLNGYFQQMGLRNTNFSRNIMDITKY-YRGIENYTTASDIAQILDKIYHYQLVSPEASE -RMLTLLKKQEI-RDRLPRYLPGYVEVAHKTGLFDN-VCHDAGIIFHPRGD-FLISILVSD -HQE-HRLAKELIGQVAKIAFEYy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Apibacter muscae TaxID=2509004 RepID=UPI0011AD302C ------DSIQNVIKDKQATVGVGVIY-HNNDTL-SINNQYLYPTMSVYKFHQALAILNYLE -KNKLSLNTSYFIKKEDLDPYSPLFKERPEGNISIKDLLYYSLCLSDNNVSNYLFNYLVSP -VQTEDYIKSLGTDEISIKGTEKEMSQNHDNQYLNWTRPLATAILFNKILNKKIFKDEYQD -FLIETLIKTNTGENKIKGLLPKDLIVGHKTGNSYRDADNDAGFVLLPNGKKYTLAIFIMN -SKETDEVNASMIAKISRLIYNYy ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus provencensis TaxID=2058289 RepID=UPI000CFA3D94 ---KWQASLEALCQNSSGQVTLSFYDEKLRHGF-SVGGSCAVLSASTIKLLVLAEVFRQAE -EGSLSLAEGVTLTAEKRTGGDGILKELLSGHFTLKELCTLMIIVSDNEAANLLLDRV-GM -DKVNQLGEDLGLTATHLGRKMMDSAA-RDAGRDNWTCADDLVLLLRGIYEGTLVSPHASK -TMLEMLKRQQQ-GDRLQRYLPEDVPLAHKCGDLK-GVENDCGIFLLPDH-PYILAVLTQQ -QP-DSLTGKRTLGTLGKLVYDH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingomonas sp. TaxID=28214 RepID=A0A520IM74_SPHSX --------------------------VDDGWTV-EAGGRQQLPQQSVSKLWVAMTVMDLRD -QGKIRLDEPIVVRPQDLTLHQPIAMLVKGDGTTVGELLTRALTHSDNTANDRLLTRVGGP -SAVRSMIARKQLGAIRFGPGERLLQSAYVRNPPDGAAPIAIADAIARLAKGDLLSETSTK -ILLDTMGRSVTGRARLRAALPGGWEIAHKTGTGQNAGFNDVGLLTAPDGRRYGIAVMIGD -TIRPMPERQKLIQAAAAAVANY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A520X479_9SPHN ---RLDNALYEIGSLFDGYLGIAIVDVERGRTV-HFGGNQLFPQQSVSKLWVTLAALEQVD -AGKLSLDEPVLVGYSDLTLHQPIRNIVLARGGDFGDLMRRAITASDNTANDRLLRRIGGP -EAVRKTIVRNRLGAIRFGPGERAMQSSYVAKPVDGATPIAIAGALARLARGELLEPATTR -IFLDLLRDVKSGPNRLKGGVPPGWTIGHKTGTGQQAGFNDVGLLTAPDGARYAVAVMIGR -TAVPVPERMDMMHRVVAAVARY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4IDW1_9NOSO ---QLDAQIKQLMNRYSLSPGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFQEID -AGRVRPNETLVMRRDLMTGGSGNMQYRKAGTFSLMETASKMMIISDNTATNMIIDRLGGK -NRLNQKFRSWGLQNTIIRNLLGDFKGT------NKTSPKDLVRLAAMISNNKLLSLNSNA -QVMDIMSRCHN-RSLLPVGLGKGAVIAHKTGTLGR-VLADAGIIQTASGKRYLAGIMVAR -PFGD-ARAKAFINQVSRLVYG-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus borstelensis TaxID=45462 RepID=UPI00046863FA ---SLENALSTLLEKSGGQWGIYLEDLQTNEIW-GKGHDDRFYAASVIKVPIMAAVFAEAY -AGKFALEDKLTLRQEDQVGGAGILQHMTPGTWSIYDLTTLMIIQSDNTATNMLIDLV-GA -EAIRSVMNKTGMVNSQFHNKLMIVPAELEG--YNEVTAADLGSHLRHLATGKIISYNSCL -HMINIMKRQQH-RDRIPYHLPPKWELAHKTGTVTR-TTHDIGVMYIGNRA-VTICLLSKN -IE--TVAANDVMAQIGRMVYDLy ->[subseq from] serine hydrolase n=1 Tax=Sediminibacterium roseum TaxID=1978412 RepID=UPI00137B4186 ---ELLNNIKATLAQEKGTFAMTFIDLQTKQML-VINEHENFHAASTMKTPVMIEVFKQVA -AGKLSLQQMVTVKNESIVDSSTYSYTKVGRQVPLSELVYQMIILSSNLATNLVIELV-DG -KNVTQTMRTLGANDMQVLRGVEDTK-AFQKGLNNTTTAYDLAIVFSKMAEGKIVSPQACD -EMIKILLDQQH-NTVIPALLPKEVKVAHKTGSIT-GVHHDSGIVFLPNGKKYVLVLLSKN -IE-SDKAATGAMARVSKMIYD-- ->[subseq from] Serine hydrolase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A2L2WT04_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRITIRELIEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSIAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas sp. Leaf28 TaxID=1735695 RepID=UPI0009E7D948 ------NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGVTLGLSLLAQGKLLSARSTT -SLLTLMRSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRKPIPARMRLMGDLTRAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52915 TaxID=2653852 RepID=UPI0014085AE7 -----RRAVEGYEKDHAGIAGAYVVDPGGGLGY-GVRADEPFFGASVMKVPVMVAVYRRID -EGELALSDMFETEEGDWAAGAGWLQWEEPGEHTVEDYLYMMMTQSDNVATNALIRKVGGL -EYVNEVAKDLGAKNTVLRQKVTS-ERAIVTGLDNQTTPRDMATMLAEVATGDAASEISCE -DMLDLMYQNVT-DRWLEAGLPDDVYAANKTGWLYK-VYDDAGVVQEGE-HPYVVAIFSKH -GPDDVEAGKELIKDVSESAWK-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P4200 TaxID=2040295 RepID=UPI000F63498B ---KLEDKIKNIIDNSGGDISVVFKNLKNNYCI-NINENKVFPSASTIKLVIMATFLKKVR -DGLVKLEDNIVLLNSHKCGGDGILKELNEGHFTYKEIITFMIIISDNTATNILIDFL-GM -DEINSMAESLNLKHTRIKRKMMDSE-AVKQGMDNFTTAKDLASFLTLLYNKEIINENYSY -IMLEILKRQQV-KGRLDLYLPEDLCIAHKTGDLDR-LEHDVGIVYTKNIN-YIICVLTSN -ID--NKNGREFIGRISKQIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Solibacillus silvestris TaxID=76853 RepID=A0A1A7M1U0_9BACL -----HKQLDRIIAQCPYKVHVIVEDYKTNEIVwENRAEEIFSSASIIKVPILIAILAHLQ -KTNGSLNQVFKIAPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM -DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA -VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFLEVRD-YFIGVFITE -VT-DNDKARQTIGAISKIVYEHf ->[subseq from] serine hydrolase n=1 Tax=Paucisalibacillus globulus TaxID=351095 RepID=UPI000BB80B01 --kELTERITQITEDAGGTWGISLQDSGTGESW-ELNGHELFYSASVIKIPIMIAVFAANH -RNEISLSNRLTVKREDMVGGSGVLQHMTPGILSITDLMTLMIIQSDNTATNMLIDLV-GT -EAIQQTMKDIGLVKSKFFHKMMTQEVD--RKGFNEITAHEMTDMLKKIATGKIISVYACE -QMIDILKKQQI-SNSLPAKIPEQWEIAHKTGNVS-GIRHDVGVFYVGKR-TLIASVLTKG -LN--NLESPEIIGRIGLEIYQY- ->[subseq from] Beta-lactamase n=1 Tax=Pedosphaera parvula (strain Ellin514) TaxID=320771 RepID=B9XGI6_PEDPL ---KTETQLQEIISHTRGAMGISVLDLTSNDRF-DINAEMVFPQASAIKIPVLMEVYKQAH -AGKFSLTDTRRIEKQDKTSGSGILFELGDGTMTIHDLCILMILISDNTATNLLIDLV-GI -TNVNQTLNSLGFEQTRLQRRMMDAAASLRGD-ENLSTPAEGVRILELLHKGEFINRSICD -DILAILKKPKP--TNLTAGLPDGTVVATKPGNIS-GVATEWAIVYLKDR-PYIVVIMENY -GVEH--DAPDAMKAISQTLHEYf ->[subseq from] Uncharacterized protein n=1 Tax=Rhodothermaceae bacterium RA TaxID=1779382 RepID=A0A1V0DF68_9BACT ---DLHARLEPLFARYEATVAVAVRDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE -AGRFSLDDSLLVRNTSIVDGSTYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA -DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLFDALRRGAAVSPEADR -AMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG -ID-DRARSAELVAEVARAVHQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:598 TaxID=1262743 RepID=R5C210_9BACE --tQLRTELQTYTDTLDAQIGIALL-LENGDSL-TLNNRQHYEMMSVFKFHQALAVCNYLY -HHNQSLDTLLHITPDDLKPWSPLRDRYLQEKISVRNLLEYTLQQSDNNACDILFDRLVSP -TETDRFIRSQGLTDFGIAYTEADMQKDHHLSKGNWSTPYAAASLLKHFLETDLIKEPYKA -FIKETMTSCQTGMKRLPAPLHTKAIIGHKTGSGYIGATNDLGFITLSDGTRYILAVFVKD -SGYNATQTEEIIGQISQIVFNH- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3C1X2M3_9PLAN --qTLEDRIRPLVQAHRGNAAVAVRHLDSGEQF-LWRAEIVQPTASLIKLPLMVTAYRQID -AGQLDAARMLTLAEADKVPGSGILTGHFSAGLSVRDAIRLMIRYSDNTATNLVAREV-GL -PATAACMQELGYSETRLNSFVYRGDTTIAPERSGSTTALETVGLLEQIQRGTVASADSCR -AMLQHLESCED-SAMLAARLPKGTKIAHKSGAVA-ASRTDAGLIYGPTG-VFAICVLTTE -NEEDSNAAHDLIATVARAAWDHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8DFH9_9BACL ---SLSPSIAKVLEEAGGQWGVYVEDLQTGEQL-AFNQDERFYAASVIKVPIMTAVFSEVY -AGKFALDTKIALRSEDQVGGAGILQHMTPGSWTVQDLVTLMIIQSDNTATNILIDLV-GR -DAIRAAMQATEMTNSRFYNKLMIVPAQVEG--YNEVTAADLGNHLRYLATGKVISYDSCE -RMIAILKQQQH-RDRIPHHFPPSWEFANKTGSVTK-ITHDMGILYIGSRA-VTICVLNKG -LE--QRPAVQAIAKIGKLVFDLy ->[subseq from] AMIN domain-containing protein n=1 Tax=Scytonema sp. UIC 10036 TaxID=2304196 RepID=UPI0012DAC637 -------QVKKLMSRYSLSPGMFFLDLETGNYL-DIYGEKVFPAASTIKYPILIALFQDID -AGKIKLNETLVLRRGLKAEGSGVLQKPVGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLARLSVMIDNDKMLSNTSRA -KVLGIMRRVQN-RRLLPSGLGKGATIAHKTGTLGI-ILGDAGIVELPTGKRYLAGIFVKR -PFGD-TRAREFISQVSKLVYG-- ->[subseq from] Class A beta-lactamase n=1 Tax=Fusobacterium sp. CM1 TaxID=936561 RepID=X8HRV2_9FUSO --tEWKKEIEKIISQVEGSVCINFYDLAKNTGF-SIDGDKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKKASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIEDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus beijingensis TaxID=1126833 RepID=A0A0D5NJ11_9BACL ---ELRSNIEQLTGQAGGMWGVTVTDLHSGEKM-TLNGSEPFNSASIIKVPIMAAAFAAVY -DGELALGSRIECRLDDMAGGSGIMRHLTPGVLTVNDLITLMIIQSDNTATNMLIDAL-GT -NRIQATVAELGMTNTRFYHKVGLMMAQPE--GRNTITADDAAIMLTRLGEGSFISRHACQ -QMIDIMKNQQY-RNGLPQQLPAAWELANKTGWVD-GIQHDAGILYAKGRA-VAVTVLSRN -GG-TPSEALACIAAIGREVYRY- ->[subseq from] serine hydrolase n=1 Tax=Runella limosa TaxID=370978 RepID=UPI000404EC73 ---SLKETIQARLKTVEGEFGVAFKDLQTQETL-FINGHENFHAASTMKTPVMIEVFKQAK -AKKFNLTDSILVKNESIVDGSPFKYRQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KNANATMRQLGAQDIQVLRGVEDTK-AFQKGLNNSVTAYDLMLIFEKIALKKAVNKKACD -AMIRILLDQKF-NEIIPAQLPTNVNVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKK -LTN-PKEGVKALADISRLIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Nostoc commune NIES-4072 TaxID=2005467 RepID=A0A2R5FYC4_NOSCO ---ELKTPIKALMARYRLTPGIFFMDLQTGDYF-NFNGDKAFSAASTIKYPILIALFQEVD -AGRIKLGETLVMRRKHVTGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGV -SKLNQKFRSWGLQSTVIRNMLGDFKGT------NKTSAKDLVRLSALVTNNHLISDISQS -QVLGIMIHCHN-RALLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacteraceae bacterium TaxID=2026738 RepID=A0A2E5DND4_9SPHN ----LESRIAQLADGSNGRIGVYAVDLTSGREI-GVLADQRFPLASTSKVAIAATYLAGVD -EGRWSLTSEYRLPR-------------PGGAMPAYRHLSLMISKXCNDCTDALLNAVGGP -SAVNKWMRGAGIEGFELTRNIATLIRAWSVDTKDSATPRAMGQLLAGIYQGKWLSEHSRR -VLLDAMLETTTGKRRMRSVLPVSANLAHKTGTLAR-TASDIGIFLTPDGRAIAAAIYVTG -QSPSMA----------------- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG11_big_fil_rev_8_21_14_0_20_64_6 TaxID=2014311 RepID=A0A2H0PC50_9BACT ---EMTGRLAKMAVKYPGRVSIYLKDLKTGRTW-MHHPDDLFPAASLIKVPVMIAAFYKIR -DGHLDLDERIAITRRNRVGGSGSLKWRPDGTLSVRELLVHMINESDNTATRMVLDRI-GI -GYVQQQFPRMGLLYTGIYEEGMSIKGG-RVMHENYTTAREMSMLMDKIYSGKAVDKVSSE -VMLGILKKPKAVASRLAKGMPRGWEIAHKTGLLRQ-ACHDSAIFMTPNGD-YALTVLTGQ -NR-SYSTAKDFITKAGKVTFNHy ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI000858A0EE ------------------------------------------------------------- -------------------PYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. JS21-1 TaxID=1855283 RepID=A0A1H7RM44_9SPHN ------------------------------------------------------------- -----------------------------------SRVMELMIVRSDNQAADQLLAAVGGP -VVVQQWLNAHGFSGIRVDRTIAQLLRGHLADVKDVATPTAMVAFLSRLEDATVLTARSGA -YLFDLMRRCATGTRRIRALLPPGTTVEDKTGTLD-GVTNDVGFITMPDGHRVAIAIFARG -GR----DRQPGIAAVARLVYDRf ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides togonis TaxID=1917883 RepID=UPI00094AF462 --tQLRTELQTYTDTLDAQIGIALL-LENGDSL-TLNNRQHYEMMSVFKFHQALAVCNYLH -HHNQSLDTLLHITPADLKPWSPLRDRYQQEEISVRNLLEYTLQQSDNNACDILFYRLVSP -AETDLFIRNLGLTDFGIAYTEAEMQKDHHLSKGNWSTPYAAASLLKHFLETDLIKEPYKA -FIKETMTSCQTGMKRLPAPLHAGAIIGHKTGSGYIGATNDLGFITLSDGTRYILAVFVKD -SGYNATQTEEIIGQISQIVFNH- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Nostoc TaxID=2593658 RepID=A0A235I2L4_9NOSO ---ELKTPIKALMARYRLTPGIFFMDLQTGDYF-SFNGDKAFSAASTIKYPILIALFQEVD -AGRIKLGETLIMRRKHVAGGSGDMQQRVGTKLSLLQTATKMMTISDNTATNMIIDRLGGA -SKLNQKFRTWGLQSTVIHNMLGDFKGT------NKTSAKDLVRLSALVTNNQLISGTSQS -QVLGIMIRCHN-KSLLPSGLGSGANIAHKTGTLRF-VLGDAGIIETPSGKRYLAGIFVRR -PNND-IRARDFIRQVSRVMYGYf ->[subseq from] AMIN domain-containing protein n=1 Tax=Aphanocapsa montana TaxID=327565 RepID=UPI00140E1ECB ----LTQRLAALHSQYAVDPSVFVLNLNNGDYA-DLQGGAPFPAASVIKLPILIAYLQDLD -AGKVSLDETLVMRPELVASGSGYMQDLPDWSFSARYTLTQMIETSDNTATNMIIHRLGGP -AYLNRRFQSWGLKDTQIRNWLPDLSGT------NTVSSHDLATVLTKVVKGNLLSSQGRQ -RALYILKLTQT-RSLLVPGIGRGASIAHKTGDIGF-ALGDAGIVFMPGGQDYVISVLLRR -PYND-PRGRDYVQRVSKTVYAYf ->[subseq from] serine hydrolase n=1 Tax=Larkinella sp. C7 TaxID=2576607 RepID=UPI00111143CA ---------------AQAQVNVAFESLTDDTRF-FHRPDELVPSASVIKIPIMIETMEQVK -AGKFDLEKVHVLLASEKTGGSGVLQTYPDESLTNLEVLTLMMIRSDNSATNILIREL-GM -DNINRRMQTLGLTQSRLNRVMMDTLAA-KQGRENRVTAREMNLLLKKIYRNEVATPALCA -QMIDILKRNAD-QTTFRLFLPKSAVIAHKTGELTY-VRGDAGIFYVT--RPFLLSVFVQG -TT--TPEAEKIIGEIAAICYNQy ->[subseq from] Serine hydrolase n=1 Tax=Larkinella knui TaxID=2025310 RepID=A0A3P1CX28_9BACT ---QLRRQIEAELAKQPGRFAVAFKDLSTGEQL-FIREREEFHAASTMKTPVMIEVFKQAA -QHRLSLSDSVLVKNESIVDGSPFSYKKVGTKRTLYGLMYDMIILSSNLATNLIIDLV-EA -RNVTQTMRDLGAKDIQIRRGVEDTK-AFQKGLNNTTTAYDLLVIFEKIATGKAVSPEASE -AMIKVLLDQHF-SSVIPAKLPKEVKVAHKSGSFAT-VRHDSGIVYLPDGHKYVLVLLSKE -MK-DDAAATETLASVSGLIYQY- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas aurantiaca TaxID=185949 RepID=UPI000D3802D8 ------NAVQALGAGFDGAVGISVRDIDEGWVV-AWEGDTPRPQQSVSKLWVAIAVMDAVD -RGQMSLADPVTVTRSDLTVHQPIRALVGPDGTTIGALLSGAMTRSDNTCNDVLLWRVGGP -VAINRMLAAKGIAGVTFGPGERHLQARYLAAPIDGASSNGITLGLSLLAQGKLLSARSTT -SLLTLMHSSKTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPDGHRYAIAVMIAS -TRKPIPARMRLMGDLTRAVVA-- ->[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLC1_9BACT ---SLTYQIKEIIAGKNAQVGVAIIHGDETWTI----GQGKQSLMSVFKLFIAMQVLDKLE -KDKTDINQMVTITEDMVDRYTPMLKVYPQTPIPMIKLIEFMVSESDNNAANFLMEYTGGA -EGLENYLKQLGFPEIEIKVSEAKMTADVKSQLLNKAYPMDVIRLLKQVREGNFLSDKNKK -LLDEMLIKTMTGENKIKKYLPSEVVIGHKTGSSDTGADNDVGFVRLADGCEYYLAVMVTD -SSLSDEDNAELIAKVSKVVYDNf ->[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus contaminans TaxID=694055 RepID=UPI00064DF7F0 --kQLTKRIQEIIKHAGGTWGISLEDLTTNEAW-GLNTEESFYAASVIKVPIMIAVFDAHH -QGALNLTDTVHLDRDALVGGSGVLQHLTGTRFTIHDLLTLMIIQSDNTATNILIDLL-GV -EKIQQTMEKQGLVKSKFYHKMMTVPVD--REGINEITAREMTVMLKKLVTGKIISAYACE -QMITIMKKQQI-RTTLPGKIPTNWEIANKTGSVS-GIRHDIGIFYVGKR-TLVAAVLSKD -VD--DIRAVDALGEIGLEIWQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFJ3_9BACT ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRADLPTSWT----------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium SM23_72 TaxID=1703777 RepID=A0A0S8IJE0_9BACT --nRLNQEIGQEIGQFKGEAGIVIRDLDKDWEL-FYKKETLFPSASLAKIPLMAGSFLAAQ -EGRLKLERNVKLKSTDKFSGSGVLKDHPGVEFSVEELIGLMIYDSDNTATNMVTGMV-GT -DYLNNFFKNIGLKNTNLSRRIADYSLR-KRGIENYTTAEDMARILEKIYRKTLINKEISE -RCLKLLKLQRL-NDRIPKYLPAELTIAHKTGLER-GVCHDAGIVYTPKGD-FLICVLTKH -KNANSIPSKEFIARISLYVYRYf ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A2S0K6S7_LYSSH -----QPTIQRIIQEAPYKVHMFVKDFKTNDFViNERLDEAFSSASLIKVPILIAVFDYID -VCDIPINQVIAISPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDVI-GM -EALNKYFHKIGLTHTQLQRKMMDFER-LAKGIDNITTARDMAHLFSQIYRQNLLSPVLSQ -LAIDILCRQRF-HECLRRYIVDDVTIAHKTGGLDT-VDHDVGIVYSHVQD-YGIGVFISE -VKQN-DVARQLIGRLSKVVYDK- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFH9_9BACT ------------------------------------------------------------- ------LNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDATTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWT----------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I2D2_9BACL ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDRIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMIAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHVy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9BBA2_9BACT ----AESAIVTRIAKSGADVGVYFKTLDGKSVW-SSRAEDVFHAASTMKIPVMIELFHQVN -QGKLKLDDPLTIKNESIVDGSIYTYKAEGQTRTVRQLCELMITVSSNFATNLLIEKL-GV -ENIRATVHALGADGVNVLRGVEDD-KAYEKGLNNTTTARGLAILLQAIAEGKAVDAESCK -EMIAVLERQKF-NEGIPAGLPQGTPVAHKTGEITK-IHHDAAIVFAK--RPFILVILVRG -LV-DIKESSALMADVSKSLYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon RBG_13_52_12 TaxID=1797379 RepID=A0A1F5DSE9_9ARCH ---------------FEKVIGVAVKHLGTGEEA-SFNGDVLFPTASVFKVPVIVELYRQVE -AGKLSLDDKMVLKEAEKVPGSGILKELSEGLVTIKDLSRLMMILSDNTATDLLVERV-GK -DNVNAAMQRLGLNKTTVVADCRDLLFSLGTEKNDVTTPLEMNKLLGLIVEGKAAGRVGCE -AILATMEKCQTGEYRVPKYLPESVKMNRKTGSLP-GIRNDVGVITIKTGEKYCISCFTKG -AP-DVYAAEETIARISRNVYQYf ->[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR43 TaxID=1076522 RepID=UPI00047951DF --eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHESFHAASTMKTPVMIEVFKQAE -AGRFSLNDSIPVKNTSIVDGSPYKYHQTGTKMLLKELLRQMIIRSSNLATNILMEMVSG- -TEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK -SMIDVLLDQQD-NSVIPAGLPPVVKVAHKTGSIT-GVHHDSGIVYMPDGRQYVLVLLSKQ -LA-DDAAATKAMSRVSGLFYDY- ->[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522L995_9BACT ---KLKKDIGNKVGHFRGTVGMVIEDLDMGWKI-TFNEDTLIPSASLVKVPIMLSCFYAAQ -DGKISLKDAISLKSSEKVSGSKVLGKEPPGAFTVEELFNPMITQSDNAAANVLIDFL-GL -DTLNRYFKKMGLKNTNIARRMMDFVER-RAGEENYTTAQDMAYLLEELYYRKFLNKEVSE -KCLKLLGEQKI-NDRIPRKLPRGTYVVHKTGLEKH-VCHDVGVVFTNKGN-FLICVLAKH -EDRLAKHAKRFISDVTLLTYNYy ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0001B8F083 --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSDHFTLKELATLMIIVSDNQATNILIDFL-GM -KNINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG -MP--NFQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase class A n=2 Tax=Chitinophaga japonensis TaxID=104662 RepID=A0A562TDF4_CHIJA ---TIKQRILDTLAGHPGIYAVAFRNLVTGEEI-LIREKETFHAASTMKVPVMIAVFKQAA -AGRFSLSDPIMVKNTSIVDSSEYEYRQVGTRRTLSDLVYRMIIKSSNLATNMVIELV-GG -QYVTQTMRELGAQDIQVLRGVEDGK-AYRAGLNNTTTAYDLLLIFEKMAQGETVSPAASE -DMIRILLDQRF-NSIIPAQLPAGVKVAHKTGEIT-GVRHDAGIVFLPDGRKYVLVLLSRE -LEN-PEEGAQAMATVSRMLYDH- ->[subseq from] Uncharacterized protein n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1IFD0_9ZZZZ ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPG------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8QBV1_9BACT -----------------------------------------------------MAVLKRID -NNTLTFDDKITVRPRDFVSEFSIATKYPKGALPVRELLDYMISESDGTACDVLMRMLGGP -EAVTINLREWGVNDIKLVTYESDMFKTPSVSFLNWSSPEAMVQLLKLLQTEKVLSAERRD -ILLSLMIKSRPGQQRIKGLLPPGTMVAHKTGTSDTTATNDVGIITLPNGQHLAIAVFVST -TKADEKTREDVIAKFARAASDCw ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A514ZUY2_9BACT ---ELRQKIETELSRQTGIFAVAFKDLATGKEL-LIRERDVFHAASTMKTPVMIEVYKQQA -QGKLSLSDSILIKTESIVDGSPYTYKQIGTKRTLASLVYDMITVSSNLATNLIIERVGGP --NVTQTMRDLGAKDIQVRRGVEDSK-AFAKGLNNSTTAYDLMLIFDKIATGQAVSPEASK -AMIATLLEQKF-NDAIPAKLPKTVKVAHKTGSIV-GVRHDSGLVILPDGRQYVLVLLSKD -IK-DDKATSGAMATVSEWIYQY- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=A0A174J2U0_BACVU --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSRITIRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGALEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIIAEVSKIVLE-- ->[subseq from] DUF3471 domain-containing protein n=1 Tax=Sphingobacterium alkalisoli TaxID=1874115 RepID=A0A4V5LYX8_9SPHI ---DLKSRIQKIMAKQEGRFAYAFMDLQTGEQL-LFNAQEMFHAASTMKTPVMVEAFKQAA -EGKFSLSDSITVYNNSIVDKSKFSYARLGKKMTRHDLIFRMITASSNLATNIIIDQV-GA -KNVMKTMKSIGADDIRVLRGVEDSK-AFQKGLNNQVTAYDLMLIFERIAKGNLINKTASE -GMIKILKAQKF-NSIIPAQLPDDVEVAHKTGSIE-GICHDSGIVYLPGGRSYVLVLLSGK -LK--DADARKTLADVSRQFYNYf ->[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR53 TaxID=925409 RepID=UPI0004794A83 --eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHASFHAASTMKTPVMIELFKQAE -AGRFSLNDSIPVKNESIVDGSPYKYHQTGTKMLLKELLRQMIIRSSNLATNILMEMVSG- -TEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK -SMIDVLLDQQD-NSVIPAGLPPGVKVAHKTGSIT-GVHHDSGIVYMPDGRQYVLVLLSKQ -LA-DDAAATKAMSRVSGLFYHY- ->[subseq from] class A beta-lactamase n=1 Tax=Bacteroides paurosaccharolyticus TaxID=732242 RepID=UPI00046A56BD ---TLEEMINRKIREVKADVGVAII-INSKDTL-AINNEHNYPMLSTYKVHQAMKVVDFLR -EKSVPLTNEIEIPASQLKSYSPLQQKYPSGVLPVSEILRYSLQLSDNNACDILFSLVGGP -MVVNRYLESIGVHDCNVAYTEDEMRQDINRAYDNWTTPLEGAIVMEKLFCGEIGDDQYSS -FIKEILYNSKTGEKRIPCLLPKDIKIAHKTGTGPKKGVNDIGFIELPNGKHYSIAIFIKD -SYEDMQRNELLIAEISEIVFN-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_2_54_15_9cls TaxID=1805418 RepID=A0A1Q6WW96_9BACT --kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ -KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR -DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA -GLIKQLSTKK--DSYIPRLLPDDVQVANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY -DR-DEKAAERAISDVALEAYQYf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00098F7BE0 ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=1 Tax=Rufibacter ruber TaxID=1783499 RepID=UPI00082B137F ----VKAAILAELGKQEGTFAVAFKDLETGEEL-LIQEHERFHAASTMKTPVLIEAYRQAA -QGRFSLQDSLLVKNESIVDGSPFSYSLLGQKRPWSELLYKMIIHSSNLATNLVIEQL-DA -QKVTQTMRQMGAQDIQVLRGVEDTK-AYQQGLNNTTTAYDLLLLFQQIAQGKAVSPAASQ -EMIQILLDQKY-KDIIPAKLPREVQVAHKTGWIT-GVRHDAGIVFPPNGHPYVLVLLSKG -LS-DEQAGIKAMATVSEMLYG-- ->[subseq from] All4822 protein n=2 Tax=Nostocaceae TaxID=1162 RepID=Q8YMV4_NOSS1 ---QLDSQIKRLMNRYSLSAGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFEEID -AGRINPNETLVMRRDLMTGGSGTMQYRKAGSFKLMETASKMMIISDNTATNMIIDRLGGK -NRLNQKFRTWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALISNNKLLSATSNS -RVMDIMSRCKN-RSLLPVGLGKGAVIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGIIVAR -PFGD-ARARAFINQVSRLVYG-- ->[subseq from] Beta-lactamase n=1 Tax=Brevundimonas abyssalis TAR-001 TaxID=1391729 RepID=U3ANB0_9CAUL ------------------------------------------------------------A -RGEERLDRALPITSDDMISHAPVTGPAVGGALTIEALCRSTVELSDNPAANILIREMGGL -DSWRNWYRSIGDSVTRVDRLEPELNLV--GDERDTTTPTQAVANMARLLAQTRLTAAHQT -LLERWLTDSPTGPNRIKAAAPDGWRVGHKTGTSSLGPVNDIGVIWPPEGAPIFVAAYYEG -PPDDFAAGEAVIAEAVGRALEA- ->[subseq from] Beta-lactamase class A n=1 Tax=Pontibacter mucosus TaxID=1649266 RepID=A0A2T5Y1U0_9BACT --dDLRQQINATLGAQQGTFAVAFKDMQTGKEL-LLNAQESFHAASTMKTPVLIEAYRQAS -EGRFSLSDSILIRNESIVDGSLYSYTLVGQKRPVSELLYKMIIQSSNLATNLVIAEL-DA -KQVTQTMRELGARDIQVLRGVEDSK-AYERGLNNTTTAYDLLLLFEQIAAGKAVSPEASQ -DMIRILLDQRH-REIIPARLPEGVKVAHKTGWIT-GVRHDSGIVILPDGRKYVLVLLSKD -LK-DEKAAMEAMATVSEMIYKY- ->[subseq from] Beta-lactamase class A n=2 Tax=Hydrobacter penzbergensis TaxID=1235997 RepID=A0A1H2T4R0_9BACT --eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHESFHAASTMKTPVMIEVFKQAE -AGRFSLNDSIPVKNASIVDGSPYKYHQTGTKMLLKELVRQMIIRSSNLATNILMEMV-SG -AEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK -SMIDVLLDQQD-SSVIPAGLPPGIKVAHKTGSIT-GVHHDSGIVYMPDGKQYVLVLLSKQ -LADD-AAATKAMSVVSGLFYH-- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520DV48_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -RRVEAVRRAMGVKAGDLQRTIDEAYARYYKHQRNSATLEAYGTLLEQLVRGKLLSPASTQ -RLFTAMKFGPPGGYRLAGGLRQDVKFIHKTGTQYR-TACHVGVVNPQDGAKAIVVASCAR -DLDDQREAGKVFTEVGRAV---- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8Q5M8_9BACT ------EEVLAELGKQEGTFAVAFKDLKTGEEL-LLNEHESFHAASTMKTPVLIEAYKQAA -EGKFDLTDSILVKNESIVDGSPFTYTQLGQKRPLSELLYKMIIQSSNLATNIVIEKL-DA -KNVTQTMRALGAKDMQVLRGVEDTK-AYRQGLNNTTTAYDLMVLFQKMAQGKVVSPAASQ -DMIKVLLDQKF-KEIIPAKLPQDVKVAHKTGWIT-GVRHDSGIVFLPNGRQYVLVLLSKG -IA-DDKASVAAMANVSEMIYRH- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A4S2FVF4_9BACT --kAIEKALLEYVSDKDARIGIAVI-VNGTDTI-SVNGKRDFPMMSVVKFPLALTVVQWID -ANGLSLNDSIAFSQKALKEYSPMLKRYGKKRMTVRELLEWSLVESDNNASDILLNHVGGI -SGATKIMKKIAIDNIEIGASEDDMHRDPYLSYLNRTTPLAMAELFDRFDNEMRNTSLSYS -EIATMLEQCRTGIDRLVAFLSSDATIGHKTGTGFISAINDCGYVNLPNGARYSIAVFVAD -SGYDMAETSAIIAEISRIVW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) TaxID=886293 RepID=L0D6A5_SINAD ---ELERTIRTLVEG-AGDVAVAYCRLSDGEQV-FIKGDERFHPASTMKVPVMMEVFRQAE -EGTLALDGRIRLKNESIADGSRYSYRHLGDERTVRDLVRLMITESSNLATNLLIERV-TA -ARVSELMKSMGAGDVRVLRGVED-NRAFQRGLNNETTARGLATIFRQLAARRVVSAKASE -EMLAILRDQKF-NEGIPAGLPAGVPVAHKTGWIT-AISHDAAIVEPGGRSPYVLIVLTRG -IK-DPAKAHELIARVSRAVYEH- ->[subseq from] Uncharacterized protein n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N7F1R6_9BACT -------------------------------------------MISAFKFHIALTVLDKVD -KGELSLTQKLFFKKSELLEWSPFREKYPNGDITLKEALQWTISVSDNNLCDILIRLVGGV -KTVDNFINS---ADFIIKNDEEGMHQNWDAQFLNTTTPNFSNQLLKRFLENKLLTKKSTK -FLYKTMVSTSVGQNRIKGKLPTNTEVAHRTGSSFTGAINDIGIVRLPNGKYFIISIFVHN -TTEKFKDGEEIIADITKATWDNy ->[subseq from] Serine hydrolase n=1 Tax=Duncaniella muris TaxID=2094150 RepID=A0A2V1IIK9_9BACT --kAIENALHEYIKGKDARIGVAVI-INGKDTV-SVNGNRDFPMMSVVKFPLALTVAHWIN -TNGMSLNDTVTFSEKAMKEYSPMLKKYGKSLMTVRELLEWSLVESDNNAADILLHRVGGT -SGVTSIMRQMGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFYHELRNASQLYS -EISVMLEQCRTGLDRLAFLLPTNALIGHKTGTGFISAVNDCGYVNLPNGTRYSVAVFVAD -SNYDIATTSAIITEVSKIVLE-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7EK04_9BACT ---------TRIAQEPGAYVGLAYVDLASGDTL-FLNADSSFHAASTMKVPVMIELFRRAN -TGSFGMNQGLLMVNQSLVDGSRYAYHRIGDRVSVDTLLRLMITRSSNFATNTLITLV-GA -EEVTRTMRALGAQRIQVLRGVEDGK-AFEKGLNNTTTARDLAIILRAIQEGKAASPPATR -EMLAILLAQEF-NEKIPAGLPPGTRVAHKTGEIT-AVSHDAAIVYPAGRKPYVLVVLTRG -IT-DGAKASKLIADLSSIIYQH- ->[subseq from] serine hydrolase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF5BCCC ------------------------------------------------------------- ------------------------------------------------------------- -ARVRKVSQLLDVPVSRLRMPLEDAYTAYYASGVNSGRLDAYGQLLALLVDGRALGRPMTD -YLLQVMERTATGTRRIKAGLPPDARFAHKTGTQRR-RICDAGLVTSPRTAARVLVVACVR -GDLSLERSERALQQVGAALC--- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2FYK9_9BACL ----LFAQISSLIKDAGGEWGIFFEDLQTGETF-SFNEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLREEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGRHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILFIGSHA-VTLSILNKG -LE--QKDAADVMAQIGNLVYHVy ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5KYY8_9BACT --kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ -KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR -DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA -GLIKQLSTKK--DSYIPRLLPDDVQVANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY -DR-DEKAAERAISDVALEAYQYf ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. I-24 TaxID=2666025 RepID=UPI00138E751A --dQLRQQINQELAKQSGVFAVAFKDLSTGQEL-FIREHDVFHAASTMKTPVMIEVYKQVA -QKRLSLADSIPIKTESIVDGSSYSYKEVGTKRTLASLVYDMIILSSNLATNLVIEQA-DA -QKVTQTMRELGAKDIQVRRGVEDSK-AFEQGLNNTTTAYDLMVIFEKIATGQAVNPEASK -AMIDILLDQRF-MSKIPAKLPKEVKVAHKTGSIK-GVSHDSGIVFLPDGRQYVLVLLSKD -LKND-QAADNTLATVSELIY--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=D1LFJ5_9BACT ------------------------------------------------------------- ------LNQRVEIKKSDLINYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIVHLGGP -DKVTAFARSLGDETFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRNLTLGKALAETQRA -QLVTWLKGNTTGSASIQAGLPTSWV----------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Vibrionimonas magnilacihabitans TaxID=669455 RepID=A0A2S8SIP8_9BACT --eQLMQQVKDTLALQKGFFAVAFRDLSTGETL-LWNEHESFHAASTMKTPVMIEVFKQAE -AGRFSLNDSIPVKNASIVDGSPYKYHQTGTKMLLKELVRQMIIKSSNLATNILMEMV-SG -AEVTKTMRSMGAKDIQVLRGVEDQK-AFDKGLNNTTTAYDLMLIYEQLSLGKAVSVAASK -SMIDVLLDQQD-SSVIPAGLPPGIKVAHKTGSIT-GVHHDSGIVYMPDGKQYVLVLLSKQ -LADD-AAATKAMSVVSGLFYH-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chamaesiphon minutus (strain ATCC 27169 / PCC 6605) TaxID=1173020 RepID=K9UP01_CHAP6 ----LDRRLQATLNRSKIDPSYLFVDLNSGEYT-QLGADRVLPAASTIKLPILIALFQDVD -AQKVQLEEKLTIDKNSIAGGSGDLQQKPGTQVSILVAATKMMTISDNTATNLIINRLGGA -TKLNQRFRNWGLKVTTINRPLPDLEGK------NTTTPRELARTMMAIDPGKLLSDSSTS -QILSIMSNT-IGNTMLPKGLGAGAKIAHKTGDIGS-TIADVGAIELPSGKKYLAAVIAKR -PYND-PDGPALVRSMSKIVYEQf ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-4101 TaxID=2005461 RepID=A0A1Z4RJM5_9CYAN ---QLAAQVRTLMARYSIEPGIFVLDLDTGNYL-DYNGEKVFSAASTIKFPILIALFQEID -AGRIKPNETLVMRRDLITGGSGNMQYKPAGTFNLMETATKMITISDNTATNMIIDRLGGK -SKLNPRFRNWGLQNTVIRNLLGDFKGT------NTTSPKDLVRLSALISNNQLLTNSSQT -KVIDIMRRVQN-RSLLASGIGKGAVIAHKTGTLGV-ILGDAGIIQLPSGKRYLAGIMVRR -PFGD-SRGTQFISQVSKVVYG-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A0D9AMM6_PSEST ------------------------------------------------------------- ------------------------------------------------------------- --RLELLARLLGVPKSELRARLREAYERYYATPNNSATLQAYGDLLAALVAGKAVSRASTE -YLLGVMTRVQTGDQRIKAGLPATVSYAHKTGTQV-ARICDAGLIAPPATGRIVVVACVRG --AASTVKAERALRGAGEAIT--- ->[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI00135AA69A --eDLKQKISEELAKHKGSYAIAFKDLKTGEEF-GINEHETFHAASTMKMPVMIEVFKQAS -QGKFKLTDSITIKNESIVDGSLYSYRHIGEKRAIKDLVYEMIIVSSNFATNMVIDLV-GA -KNVTQTMRDLGAKDILILRGVEDAK-AFQKGLNNTTNAYDLRLLFEKMALGKIVNQKACD -AMIKILLDQKF-NDVIPGNLPKDVKVAHKTGGLPN-IQHDSGIVFLPDGRKYILVILSRD -WE-SEAANRKMLAGISEMIY--- ->[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. UNC358MFTsu5.1 TaxID=1449049 RepID=UPI000AA08038 --qKLTAQFQPIADRVPGQLGVGLEDLGTGQII-SFNGERRFPLQNVAKAPLGAAVMAEVE -GKRLRLDDVLLIEDVDLSPPSPLADAWTGPSHTVQELLERAIRDGDNTAADILMKRVGGP -GAVTAWLQGRKVMNLDIDRYERQLQPAYLADPRDTATPLGALRFLEALNQAELLNADSRR -LLGGITRQVTAGPDRLRAALPRDAQLVHVPGTARTDVVNDIGVYTLKDGRKFAVVVFISG -SPLPLAEQEKAIADVGRVVIK-- ->[subseq from] Uncharacterized protein n=1 Tax=Omnitrophica WOR_2 bacterium RBG_13_41_10 TaxID=1801849 RepID=A0A1G1MBI9_9BACT -----EAGINKEILSFNGKPGSTIKDLSNNWQI-KINPNGSFPAASLVKIPIMAACFYAVN -EGRLKLDENLQLRTKDKVLGSGNLKNLASGRFSIQQLLEIMITESDNTATNMLIERI-GF -DYLNDCFKKIGLKNTNISRKMMDFKSR-RHGRENFTTASDLAFILEEIYRNKLINRKYSQ -KCLGLLKKQNI-RDRIPSRLPQEICVAHKTGLER-GICHDVGIIFTHRT-NILICVLTKH -NNKTARLAKNFIARVAFLTYR-- ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas insulae TaxID=424800 RepID=UPI0013CF630C ------NAVQALGAGFAGDVGIAVRDIDEGWSV-AWAGDTPRPQQSVSKLWVAIAVMDAID -RGRMSLTDPVTVRRSDLTVHQPIRALVGPDGTTVGDLLRGAMTRSDNTCNDVLLWRVGGP -EAIRRMLAAKRIAGVTFGPGERELQARYLAAPIDGASANGVTLGLSLLAQGKLLSARSTA -SLLALMRSSRTGPLRLKSGLRPGWTLAHKTGTGQSTGYNDVGLLVAPNGHRYAVAVMIAS -TRVAIGTRMRLMGNVTRAIVA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=A0A1I3I3G2_9PSED ----LLERLQAVAERQDGELGVYVKDLHSNLAV-TLRADERWYMASGIKVPVAIAVLRGVE -RGDWQLDTRLPLAANDFVDGAGSTNQHGPGELSVRFLLEQMIIYSDNTATDRLIRLA-GL -DTVNALVRELVPEGFEPITTLGDVRRNYYRSNLNAATLSAYGGLLERLASGQALGKAQTD -YLLEVMGRVKTGRQRIVAGLPKDARFAHKTGTQR-ARICDSGLIEAPARAEPVLVVACVQ -GQQSLAKAERSLRQVGEALT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Phenylobacterium sp. SCN 69-14 TaxID=1660128 RepID=A0A1D2TR45_9CAUL ------------------------------------------------------------- --------------QADMISHAPVTEPAVGSTLTIEQLMKGTVEVSDNPAANILIREMGGL -DALRAFYRGIGDDSTRVDRLEPEMNRQ--DGDKDTITPDQSVRNIQRLLVDTPLSPASKT -LLMRWLVDTPTGQGRIKAGVPAGWTVAHKTGTGGYGPVNDIGLILPPNAAPIAIAVYFHA -TKSTDAQREAVIADATRQALK-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. 209 TaxID=1955701 RepID=UPI00098CF9C6 ---------------ASARVSVAVESLADSSVSfAHRADERVPSASVIKLPILLEAMERVK -AGTLDLDEIHILTDTEKVGGDGVLKTYSHRSIAYRDLLRLMMVYSDNTATNIFINEL-GM -DAINARIRAVGLPRSQLNRVMMDTLAA-RQGRDNYVTCLEMNRLLKKIYHRQVATPELCE -QMLTLLKQNED-TLTIPRLLPPDVVVAHKTGTLSY-IRADVGIVYA--HQPFLLSIFVEG -LP--TAEAERTIAETARICFTYf ->[subseq from] Beta-lactamase n=2 Tax=Sphingobium baderi TaxID=1332080 RepID=T0GFC3_9SPHN --eRLLAQFQSFAALSDGTVGIAVQDLSTGEEQ-SLNGDTLFPMASTYKVAVAGKILSMAD -AGVLALQDQVPLGPA-----------LPAKARSVHDLIDLMLTHSDNDATDALVARAGGP -AAIDGWVKALGVKALRVDSDTAHLLYAFTLDPRDTATPRAMNALLAAIQLGKALKPASTV -YLLGMMERCHTGKARLKGMLPPSARIAHKTGSLN-GYGGDVGIVTLSDGRMFAISVFVMK -DYRGRETRDRIMA---------- ->[subseq from] Serine hydrolase n=1 Tax=Peptoniphilus sp. HMSC062D09 TaxID=1739305 RepID=A0A1E9AUM7_9FIRM --nKLRDAIKNIVDESPGSISVTFCDLDEGEKF-SINGNKKSPSASMIKLLIMLTIFKKVE -LGEINLNEKIKLEDENKVDGSGVLKELSCEHFSIRELLTLMIIISDNFATNILIDKV-GM -DDVNKLGRELKLLETSLERKMMDVGAK-EKGHDNYTSSEDVASILKMIYEKSFLSEEMSS -LAIDILLRQQE-RDRLQRYLPEDLKIASKSGDLDN-LENDGGIFFTEAK-NYILVVLVSG -AE-SNVAAKEIIGKISLEIYK-- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium hwasookii TaxID=1583098 RepID=UPI0004972E15 --tEWKKEIEKIISQVDGKVCVNFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKIS -EDKFSLSDTIMMTNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ -LMLEILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLEEK-VYILVVLTSR -MS--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_55_10 TaxID=1805420 RepID=A0A1Q6V723_9BACT --kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ -KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR -DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA -GLIKQLSTKK--DSYIPRLLPDDVQIANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY -DR-DEKAAERAISDVALEAYQYf ->[subseq from] Beta-lactamase n=1 Tax=Gloeomargarita lithophora Alchichica-D10 TaxID=1188229 RepID=A0A1J0A8V3_9CYAN --qALQAQLLPLTQRNKVTATLYAVDLDSGEYL-DMGGTKTVPAASTIKLPLLLALFQDLD -QGKVRLDERLTMTKPLVASGSGDMQQPVGTTFTLLDTATRMIVISDNTATNMILERLGGK -EVVNQRFQEWGLQTTAVRNLLPDLKGT------NTTSAADLVHTLALIAQGELLSQRSRD -WVLHILRSTEN-RSLLPAGLGKGAVIGHKTGDIGF-IIGDAGVVDTATGQRYLITIFIQS -SYND-PQAVQLLQELSRKSYQY- ->[subseq from] Putative class A beta-lactamase n=1 Tax=Vibrio azureus NBRC 104587 TaxID=1219077 RepID=U3CFJ1_9VIBR ---SLESAIAILEEETSSRIGVSVWDTQSNEWW-DYRGNERFPILGTAKVFVCAAMLDAIE -RNVFSKNTTVTIKPEELTTYSPYVTHWIGQPIKLTSLCEAAALEGDNTAANVIMRELGGP -QSINTFFRSIGDKSTHITQLFPT-NSSLKG---NSSKPNTMVMNLHNIFEGDRLNYEDRE -QIETWMKNTNRKKSRITPALPENWFLAERRGIAHD-SRAELFTIWREEHSPVYVGIYIKD -YDLSLQASGQLLTQVAQLVLREy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X8N8_9BACT --hELEQRLKTISDGSQGTVGLSVVHIESGKTV-SINGSSQLPLYSVYKLPLAVTVLKDVE -EKRLRLDQKIHVTPQNVVQGTTANSALWQKPYTVEQLLEFSISRSDNTSSDKLVELVGGP -LQVTERMRSLGFQNLDIHISSGEFAKT--RQNPNTGSADDLVQLLVQLHRGKILQPDQVN -LLRGFMQRATTGLHRLRGDLPRGTVVADKTGSGEAKVTNDVGIITLPRGGHLAMAVLVNG -S---------------------- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=candidate division KSB1 bacterium 4484_87 TaxID=1970772 RepID=A0A1W9RJG4_9BACT -------EIENLCADFEATIAVAFEDLQNGASF-FINEKMQMHAASTMKTPVMIEVFKQAE -EGQLSLDDSILVKNESIVDGSKFSYQHLNKNMSIRDLVYQMITVSSNFATNLLIDLV-DA -KNVTATMRSLGAENIRVLRGVEDLKA-YHAGLNNTTDAYDMYLIMKKIALKQVVSPHACD -EMIAILADQRY-KDKIPRFLPSTIRIAHKTGWIS-GIDHDAAIVYMTPDHPYILVVLTKG -IK-NHVQAQELIGKISKTIFDK- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SEM5_9BACT ------------------------------------------------------------- -------------------------------------------SWSDNTAANIVTDAIGGP -QAFTVFMRDIGDQHTRLDRKEPEMNAATPNDLRDTTTPNAIVESLRRIILCDVLREDSRA -LLTDWMINDKVADALLRATLPRTWSIADKSGAGGHGSRSIVAVIWPKNRAPIVVGIYITQ -TTAPMVDSNAAIARLGSVLAD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Solibacillus silvestris (strain StLB046) TaxID=1002809 RepID=F2F4L4_SOLSS -----HKQLDRIIAHCPYKVHVIVEDYKTNEIVwKNRAEEIFSSASIIKVPILIAILAHLQ -KTNGSLNQVFKIAPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM -DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA -VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFLEVRD-YFIGVFITE -VT-DNDKARQTIGAISKIVYEHf ->[subseq from] serine hydrolase n=1 Tax=Larkinella sp. C7 TaxID=2576607 RepID=UPI0011114DA1 --eQFRQQIETQLAKQPGRYAVAFKDLTTGQEL-LIHEREEFHAASTMKTPVMIEVYKQAA -QKRFSLSDSILIKNESIVDGSPYSYTKVGTKLPLSAVLYDMIILSSNLATNLIIDLV-DA -KKVMQTMRDMGIRDMQVRRGVEDTK-AFQKGLNNTTTAYDLMLLFEKIATGKAVSPEASQ -DMIRILLDQRF-NSVIPAKLPKTVKVAHKTGSIAS-VRHDSGIVFLPDGRKYVLVLLSKE -IKSD-AAVVESLATVSGMIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8D3H9_9BACL ---SLSTQIAQLVENAGGEWGIYLEDLQTGETL-AFNEHKRFYAASVIKVPIMTAVFAEAY -AGNIALEQKIKLRQEDLVGGAGVLQHMTPGTLTVQDIVTLMIIQSDNTATNILIDLV-GT -ESIRAAMQKTGMTNSQFYNKLMVVPAELEG--YNELTAADMGSHFRYLATGKVISYDSCL -KMMAILKQQQH-RDRIPFHFPPKWELANKTGSVTH-ITHDTGVLFVGSHA-VTICALNKG -LE--QNPAAQTIAEIGRLVYNLy ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium periodonticum ATCC 33693 TaxID=546275 RepID=D4CTL1_9FUSO --tEWKKEIKKIISEVKGQVSVSFYDLDKNMAF-SIDGNKKVLSASMIKLLILAELMRQVS -EAELSLSQKITLTDSMRVGGDGILKVLDSGHFSLKELAKLMIVVSDNEATNIFIDLL-TM -ENINALGRNLALKETFLQRKMMDSNAK-EKGYDNYTSSDDIALLLRLIYEGKLINEETSE -IILDILLQQQQ-SERLQRYLPSDTKIAHKCGDLDN-LENDGGIIWINDRA-YILVVLTSA -IP--NLECRETIGKISKYIYS-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. animalis TaxID=76859 RepID=A0A2B7YSA1_FUSNU --tEWKKEIEKIISQVEGSVCINFYDLAKNTGF-SIDGDKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELTTLMIIVSDNQATNILIDFL-GM -ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDILSLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGNKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5404 TaxID=1864824 RepID=A0A2N1KKL1_9BACT ---TLKDQITQYLADKKGTYAVAFKNLQSKQTV-YINEHELFHAASTMKTPVMVEVYKQAA -AGKFAVRDSILVKNESIVDGSTYRYTEVDQKKSIYDLMYQMIIVSSNLATNIIIDLV-GA -EKVTKTFHQLGAKNSQIRRGVEDQK-AYQKGLNNEVTAYDLAELFEKIAKGKAVNKESSK -AMIQILLDQKF-NDIIPAKLPAGTKVAHKTGSITN-IYHDSGIVYLPDGRSYVIVLLSRD -WD-TRENAIQTMATISEMVYQ-- ->[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A2I0UY60_9BACI -----EQIIEKMVQESPYNVHLFVHNLTTNQLLtSHQLETAFSSASVIKVPILIALLSYIE -HNKLSLDTTLPISPDDWVGFSVISEQRLTQ-STLYDLLVWMIITSDNTATNVLIDEV-GM -SFLNDYFRHIGLQDTVLQRKMMDVER-LAQGIDNRTSARDMAHLFTRIYRQELLTAPYSQ -LVIDILSRQRV-HDSLKRYLVEDVKLAHKTGGLDT-VDHDVGIVYSSTID-YSIGVFMTN -VM-DNEQARQLIGRLSKVVYA-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI0006FF9B3D ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINENQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIRLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVDILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAAEVMAQIGHLVYHVy ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D0EA6C3 ----LFAQISSLIKDAGGEWGIFFEDLRTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNIMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEIANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAADVMAQIGNLVYHVy ->[subseq from] Serine hydrolase n=1 Tax=Ammoniphilus sp. CFH 90114 TaxID=2493665 RepID=A0A4V1NXB6_9BACL ---SLQQKIESIASEAVGMFGVSIKHLNTQEEV-NINENRLFQTASVVKIPILAALMEEAY -KGNIDLHKRMPIREEDFVPGSGVLKEFEGVEVTIKDMATMMIIVSDNLATDKVLGLL-GA -DHVQRRMHESGMQNMYIKHSIWELLSYQESTENNVSTPKDMTRLLEMIAKGEFVSKDCSD -DIIDILLKQQL-RQRIPRLIPYGTKIANKTGSLAT-IVNDAGIVYMPNKGAFVMSVFSKG -VA-SSYDAERTIVQMAQTAYQHf ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus harei TaxID=54005 RepID=UPI0011DD7284 ---GLQNKIENIVEESSANIFVSFYDLDLGEGF-SINGDQQVPSASMIKILILLKAFDECD -KGKLNLEDTISLDDYERVDGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR -EEINKIGHELGLEKTILQRKMMDSLAK-ERGLDNFTSSNEILKLLKMIYEKNFINEDYSE -LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ -AE-SNVLAKEIIGEISLKIYK-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=A0A0M5JCM8_9BACI ---TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE -RGEFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIIMLMIIQSDNTATNILIDLV-GI -DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE -QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE -E--DDLVSKRILSEIGEAIYNY- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter sp. CAG:267 TaxID=1262684 RepID=R5YMF9_9PROT ------AAVEKIADGAGADVGVAYA---SSEKY-RQNGSRQYPLLSVFKLHVAVAVLDRAD -RENIALDSRIQIPSAEIKPYSPLREKYGVRDLPLRELLRYMVAESDNNACDILIRWLGGV -KKVAAYSRKIGLRQTEILVTETEMNRNVRLQYANKAPLSEIIRLLQLIDGGKLFAPELHK -ELLAIMEKTSTGTDKIKKYLPSFVSVAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD -SRLSDKENAEIIARIAFLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6G1A0_9BACT --kKLETRVEEIAGRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ -KGKAKLDDIYIFDPKNLVEDSRIMAGLTPGVITNRDLAQFMVAVSDNAAANILIDHV-GM -QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKEKVLNKEMTT -DFIKQLSTLKQ--SYIPRLLPDNVQIANKPGELE-AVRNDVGIVFASNR-PFVISVMTAY -DR-DEKAAERAISKVALEAYHYf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5JW90_9BACT --kKLETRVEEIAARLDGVMGVAVLDLTDGRVL-LRNADRVFAAASSIKLAILLELYRQDQ -KGKARLDDIYSFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANVLIDRV-GR -DNVNAMLRSLGLSKTVLRRKMMDIAAARRG-DENVATPQEMVRLLEAIFKEKAVDKESTA -GLIKQLSTKK--DSYIPRLLPDDVQIANKPGELE-GVRNDSGIVFAAHR-PFGISVMTAY -DR-DEKAAERAISDVALEAYQYf ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. JN-9 TaxID=2507159 RepID=A0A410PKS6_9CLOT ------ENIKRLIDENKGDIAVAFKNLKTNSSI-MINEDVIFPSASTIKLVIIAALMNEIN -KGTMKLEQTITLSDIHKCGGDGILKELKEGHFTLYEIAKLMIIISDNTAANILIKLL-GM -GNINQMAEKLGMANTKLNRKMMDSEA-VKYGKENVTTAKDLCHFLELLYNGKVINKEYSE -IILGVLLKQQL-GGRLNLYLPEGVIIAHKTGDLDK-LEHDAGIVYNYPND-YILCVLTKN -LL-SNKDGKEIIGRVSLEVYKY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5JP39_9BACT --kKLETRVEEIAGRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSQIMAGLTAGVVTNRDLAQFMVAVSDNAATNVLIDHV-GM -QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVATAQELARLLEMIYKGKALNQELTG -DLIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GVRTDSGIVFAKNR-PFAISVMTTY -DR-DEKAAERAISEVALEAYRYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. AAP5 TaxID=1523415 RepID=A0A4P6XBT4_9SPHN ------NAVQALGSGFPGQVGIAVRDVTEGWIV-GYNADRLLPQQSVSKLWVAIAVMDAVD -RGRLTLSDIVTVRRSDLTVHQPILPLVGTDGTTIAALLEGAMTRSDNTCNDVLLWKIGGP -PAIRRMLMQKGIAGVGFGPGEWLLQARYLAAPYDGASANGVTLGLARLQRGEVLSSSSTL -HLLTLMAASKTGPLRLKSGLRSGWTFAHKTGTGQSTGYNDVGLLKAPDGHTYAVAVMIGS -TRRPIAARMQFMGNVTRAIIR-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus camelliae TaxID=1707093 RepID=A0A2N3LM91_9BACI ----LMNEIQDILHRTGGTWGICLEDLDKKQHW-SWNEKEDFFAASIIKVPIMAAVFSAYD -QGQFHLSDKIVLKREDLVGGSGILQHMTPGILTIYDYLTLMIIQSDNTATNVLIDLV-GV -EKIQETMSEIGMKNSCFYNKLMTVPVK--TKGRNKITAGDMAILLHKLTSGSIISQYACE -QMIDIMKKQQF-RDCLPEQFPSEWEFANKTGWVT-GIHHDIGVLYVGNRT-MNIVVLSKD -VEN--RLAKQTMAQIGKCIFNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Mesorhizobium plurifarium TaxID=69974 RepID=A0A0K2VU99_MESPL ---NVTAEISRHSLGAEGYVGVAAWRLDGGPAL-LLNADQPFPMASTFKIAVACRILERIA -TGELGCDHLLEVPDDIRVPGSVIADRFIHPGLSVHNLLQVMLDESDNTATDVLIEACGGV -ATVTRSLEAWGVVGQRVDRDVRGLLRAFEDDLRDVSTPFAMSTLLAELFSDRLPLANLAT -VLRDIMRACRTSGTRLRGLLPPGTEVIDKTGTLG-GVTNDVGLIVLPQGGEIVISVFIKK -GCAPFEQQERVIAEIARTVYDFf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_66_21 TaxID=1797191 RepID=A0A1F2TUC0_9BACT --sDLEARLRGPIAASGAEVALAYRTLDGSAEL-LIDADKPFHAASTMKVPVMIELFRRAR -AGTLSLDDRLPIVNESIVDGSPFRYAAVGKTMTLRHLCELMITVSSNFAANLLIEKL-GA -EHIRKTVATLGADGMQVLRGVEDQK-AFDKGLNNTTTARGLLVLLDKIAHGQAVDRAADD -EMLAILERQHF-SDAIPGGLPPGTVVAHKTGTITR-IHHDAAIVYAS--RPYVLVVLVRG -LD-DQKKAAALIAEISKIVFE-- ->[subseq from] Uncharacterized protein n=2 Tax=Rubrobacter xylanophilus TaxID=49319 RepID=A0A510HGS5_9ACTN -------EAEEAVREHPGIAGFYVRDLESGAGY-GVRPDHVFFSASTIKVPVMIAVYRRID -EGRLDYSDRIVTTEEDWAAGAGWLRWTPGAKSTVEDALWLMITQSDNVATNALVRLVGGP -DYVNRVARSLGARDTVLYWKLSSERAAVP-TLDNRTTPRDMALLLARIRSGEAASRHSCR -EMLGLLEQNDL-EWWIEGGVPPGVKVANKGGWLD-ATYNDAGIVEYEER-PYVLAIFTEY -GP-DLNEGGRYLQRISRAVW--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5XXL6_9BACT --kKLETRVAEIAARLDGVMGLAILDLTDGRIL-LHNADRVLPAASSIKLAILLELYRQDQ -QGKAKLDDSYTFAPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNASANILSDRV-GR -DNVNAMLHSLGLSKTMLRRKMMDVAAA-RRGEENVATPQEMVRLLESIHKGKVLDKQSTA -EFIKQLSTSK--DSYIPRYLPDGVQVANKPGELE-AVRTDSGIVYAQNR-PFAISVMTAY -NR-DEKAAERAISEVALEAYHYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI0009EAA634 ---TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE -RGEFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIIMLMIIQSDNTATNILIDLV-GI -DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE -QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE -E--DDLVSKRILSEIGEAIYNY- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Omnitrophica TaxID=1047005 RepID=A0A2G9YIM0_9BACT ---RLKKTLENKVMNFRGTVGMVVEDLDMEWEI-AFDKDTLIPSASLVKVPIMLSYFYAAQ -DGKISLKDTIILKSSEKVSGSRVLGKEPAGSFTVKELFNPMITQSDNAAANILIDFL-GF -DTLNYYFKKMGLKNTNIARKMLDFEER-REGEENYTTAQDMAYLLEELYHKKFLNKDVSE -KCLELLGQQKI-NDRIPRKLPRGTFVVHKTGLERH-ICHDAGIVFTNKGN-FLICVLVKH -KDRFAKPTKKFISDVTLLTYNYy ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonas sp. SRS2 TaxID=133190 RepID=A0A0F5PFS0_9SPHN ---DLLNAVQRLGSTFQGRIGISVREIDAGWTV-AFAGDANLPQQSVSKLWVGVATMQQLE -QGRLSSADPITVRRSDLTVHQPLRPLVTANGTTIGKLLELAMTRSANSANDVLLWKIGGP -RTVREMLSRTGITGVGFGPGERELQARYLAAPYDGASPNGVTLGLAMLAKGKLLNPSSTA -RLLALMRASKTGPLRLRSGLQPGWTLAHKTGTGQATGYNDVGILVSPSGRRYAVAVMIAS -THQPIPVRMRLMGDLTRAVIR-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma luteum TaxID=431553 RepID=UPI0012F8B7D6 ---------------------------DTTLSF-AHRATVRIPSASVIKLPIMLELMERVE -AGTIKLDAIHSLTEAEKVGGDGVLKTYPDKSVSYRELLRLMLIKSDNTATNILIHLL-GR -DAVNQRIRKLGLERSQLNRVMMDTLAA-RQGRENYVTAQEMNTLLEKVYRYQVATPERCE -EMLAILKQNED-TLTIPRLLPKRVVIAHKTGTLAY-VRGDVGIVYTQ--KPFLLAVFVEG -VP--TPEAERIISEVAMICYTYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q6WWY0_KLEPN ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLVDGMTIGELCAAAITLSDNSAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETE------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Tolypothrix bouteillei VB521301 TaxID=1479485 RepID=A0A0C1NCF5_9CYAN -------QVKKLMSRYSLSPGMFFLDLETGNYL-DIYGEKVFPAASTIKYPILIALFQDID -AGKVKLNDTLVLRRDLKAEGSGVLQKPVGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLARLSVMIDNDKLLTNTSRS -KALGIMRRVEN-RRLLPSGLGKGATIAHKTGTLGI-ILGDAGIVELPTGKRYLAGIFVKR -PFGD-TRAREFISQISKLVYG-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6KBF2_9BACT --kKLEARVGEIATRLDGVMGVAILDLTDGRIL-LRNADHVFPTASSIKIAILLELYHQDQ -KGKVKLDDIYTFDPKDLVEDSQIMAGLTPAVVTNRDLAQFMVAVSDNAATNVLIDRV-GM -QNANATLRSLGLTKTMLRRKMIDIAAARRG-DENVATSQEMTRLLEIIYKGKALNKEVTD -QFIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GIRNDSGIIFAPNR-PFAITVMTAY -DR-DEKAAERAIGQVALEAFHYf ->[subseq from] Serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5L0J8_STAAU ------------------------------------------------------------- -----------------MVAYSPILEKYVGKDIALKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGIPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7X3B6_9BACL ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNILIDLV-GT -ESIRNAMQKTEMANSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHVy ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012F9431C ---ELRQKIEQEFSKYPGVFAVAFRNVATGEEL-LIREREVFHAASTMKTPVMIEVYKQQA -QGKLSLSDSILIKTESIVDGSPYTYKQIGTKRTLASLVYDMITVSSNLATNLIIELV-GA -PNVLQTMRDLGAKDIQVRRGVEDSK-AFAKGLNNSTTAYDLMLIFDKIATGQAVSPEASK -AMIATLLDQKF-NDAIPAKLPNDVKVAHKTGSIT-GVRHDSGIVLLPDGRKYVLVLLSKD -IK-DDKLTSGVMATVSEWIYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=I1V5A1_9BACT -------------------------------------------------FMAASAILKESE -VKKNLLTQHVALKKSDLVNYNPITEKRLNEGMAIGELPAAALQYSDNTAMNKLIEHLGGP -HKVTDYARTLGDNTFRLDRTEPTLNTAIPGDERDTTSPRAMALSLQHATLGSALAEPQRA -QLVEWMKGNTTGAMSIRAGLPATWIV---------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus mangiferihumi TaxID=1130819 RepID=A0A4U2YNK5_9BACI -----QQTIQRIIQEAPYKVHMFVKDFKTNELViNERLDDAFSSASLIKVPILIAVFDYID -VCNIPINQVIAITPSDWVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDVI-GM -EALNKYFHKIGLTHTQLQRKMMDFER-LAKGIDNITTARDMAHLFSQIYGKNLLSPVLSQ -LAIDILCRQRF-HESLRRYIVDDVTIAHKTGGLDT-VDHDVGIVFSHVQD-YGIGVFISE -VKQN-DVARQLIGRLSKVVYDK- ->[subseq from] Beta-lactamase VEB-1 (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M3R7M2_PSEAI -------------------------------------------MQSVMKFPIALAVLSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLINTYNNQLLSKKSYD -FFWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QH_7_62_13 TaxID=1919098 RepID=A0A2T2T870_9BACT ---DLKDQIQTTLDSVEGDFAVAVRTLDDTTETlLLNEHEMFHAASTMKVPVMVELYRQAH -EGRFSLDDSIEVKNESIVNGSPYSYDHIGEKRSIRTLMRAMITVSSNLATNILIEKV-GA -ERTTQTMREYGADSIQVRRGVEDMNA-YRRGLNNETTAHDLLVILERIARGNAVSAEASS -EMIDILRDQEY-NDMIPARLPDSVDVAHKTGRIT-GVRHDGGIVVVPDGPSYVLVLLSKN -LR-DETAGIATLARLSRLVFE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=C7E642_ECOLX ------------------------------------------------KVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGN--------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_57_9 TaxID=1797943 RepID=A0A1F9U874_9BACT ---AMTEELSLLASKHQGRVAIFLKDLGTGNIW-THHSEDLFPSASLIKVPLMACVFFKIR -DGQLALYDKLTLRRRHRRGGSGSLKWRSDGELTVHELLRHMINESDNTATAMILEVL-GL -NYVQQQFPKLGLVYTGISEEGMSLKSG-RVAQENYTTAREMAMILEKIYRGEMVDRPSSE -IMMDILKHRKAVTSRLAKGLPKGWEIAHKTGLLRH-ACHDAAVILTPHGD-YVMTVLTGQ -NA-SYRTAKNFIDRLGRVTFAL- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SGR5_9BACT --eRLQATLLRLSTDLDGVPGYLMRDLASGESL-ERNADIVFPVASVIKLPVLLELYRQAE -EGTLDLARPVPIDPKARVEGGGVLEKWSAPYLSAAQLAVLMMDFSDNYATNLLIDLV-GP -DRVGRRLKGWGFKETLLRRKMMDLDAA-RAGRENVSTPREMAALLERLGRGQILDADGTG -RVIAIMKRNER--TPLKRALPAGIEAADKEGELD-GVRCSVGIVFVPSGR---------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C0ZKU0_9BACT ---KFVAKIQSIAENADAVVGVAIKDLKSGDEY-LINADEILPQASSIKIHILTELYREAE -QGRYRLTDILQLPESVRVGGSGILSELGPKSLSLHDYAVLMIVLSDNTATNLLIDLV-GM -QNVNKSLQAMGASKTKLQRVMMDVKAA-KAGRENIGTPREAMMVLEKLHQGEIVSKKASE -EIVSILRKPKEG--PIRRGVPESVPVANKEGEVE-GMRCDVAIVELPES-PYIICVMTKL -LLKP-EDGPRVIEELSRASFQYf ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00114DB686 -----EQIIEKMIQESPYNVHLFVHNLTTNQLLtSHQLETAFSSASVIKVPILIALLSYIE -HNKLSLDTTLPISPDDWVDFSVISEQRLTQ-STLYDLLVWMIITSDNTATNVLIDEV-GM -SFLNDYFRHIGLQDTVLQRKMMDVER-LALGIDNRTSARDMAHLFTRIYRQELLTAPYSQ -LVIDILSRQRV-HDSLKRYLVEDVKLAHKTGGLDT-VDHDVGIVYSSTID-YSIGVFMTN -VM-DNEQARQLIGRLSKVVYA-- ->[subseq from] serine hydrolase n=3 Tax=Rhizobium meliloti TaxID=382 RepID=UPI000FD40C88 --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVEKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFSDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus harei ACS-146-V-Sch2b TaxID=908338 RepID=E4L0E4_9FIRM ---GLQNKIENIVEESSANISVSFYDLDLGEGF-SINGDQQVPSASMIKLLILLKAFDECD -KGKLNLEDTISLDDYERVDGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR -EEINKIGHEFGLEKTILQRKMMDSLAK-EKGLDNFTSSNEILKLLKMIYEKNFVNEDYSE -LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTTNK-NYILVVLVNQ -AE-SNVLAKEIIGEISLKIYK-- ->[subseq from] serine hydrolase n=1 Tax=Solibacillus kalamii TaxID=1748298 RepID=UPI000B3E6F17 -----HKQLDRIIAQCPYKVHVIVEDYKTNEIVwKNRDEEIFSSASIIKVPILIAILAHLQ -KTNGSLNQDFKIAPENMVDFSVITEQK-QIRATLHELLLWMTITSDNTATNVCIDLL-GM -DAFNDYFNEIGLHNTRVQRKMMDFERQ-KLGFDNVTTAQDMQQLFRKIYRGTLLTSEWNA -VALDILSRQRS-HESLKRYIADDVKMAHKTGGLDT-VDHDTGIVFTEVRD-YFIGVFITE -VT-DNDKARQTIGAISKIVYEHf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A059WJK3_KLEPN ------------------------------------------------------------- --------------------------------------------------MNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPR------------------- ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus soli TaxID=1543965 RepID=A0A544SYW7_9BACI --kTLVNKIRNLTKQSVGTWGIVLEDLDLGEKW-VWNEDELFYAASVIKVPIMAAVFSAVE -RAELALTDQIIIKEEDLVGGSGVLQHLTPGTLSIQDTVMLMIIQSDNTATNVLIDQV-GV -EYIVQTMKAVGMEKSTFYNKLM-MNKPNPK-GFNQITASDVARLLRLIATGELVSPEASE -QMTAIMKKQQI-KDCLPEKLPTSWELAHKTGWIP-GTRHDVGIFYVGERK-LVATVLSKE -ED--DLVSKRILTEIGEEIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6N867_9BACT --kKLDARVGEMVQRFDGAMGVAVVDLTDGRAI-LKNADHIFPTASSIKIAILLELYHQDQ -QGKAKLDDVYNFDPKELVEFSQIMAGLTPGVVTNRDLAQFMVAVSDNTAANILIDRV-GK -DNVNAMLGGLRLTKTMLRRKMMDFAAA-RRGEENVSTPQEMTRLLEAIYKGKLLSKELSQ -QLIKQLSTLKE--SYIPHDLPASMQVANKPGNLQN-VRTDSGIVFVKDR-PFAISVMTAD -AR-DERAAEHAISEIALEAYRYf ->[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC670 TaxID=2712865 RepID=UPI0013E9D802 --------VVALVAPHEAVVEVALHDLATGETV-LIRADEPIHPASTMKVPVMMEVYRRAE -AGGLGLDDEIEVKNTSIVDGSHYAYKRVGGKATIRELVFLMITESSNLATNILVEKL-TG -EAVTAFMKELGAGDLKVLRGVEDDK-AVALGRNNVGTARGTMTILTRLAEGTAVSRSASD -AMLEVLRAQKF-NDGIPAGLPEGTVVAHKTGSFAK-VYHDAGIVEPEGRKPFVLVVMTRG -IEAE-DASRKLVADVARAAYEH- ->[subseq from] Serine hydrolase n=1 Tax=Romboutsia maritimum TaxID=2020948 RepID=A0A371IRP9_9FIRM -----------------------------------------YPSASTIKLVIMGAVMKEIK -EGRINFDDKILLSRDKVCEGDGILKELDEDHFTIKEIMTLMIILSDNTATNILIDLV-GM -DAVNKIGSDMGLKYTKLRRKMMDSE-AVKNGRENTTTPKEMAKILNKIYSEEFIDENFSK -IALDILKRQQV-GNRLTLYMPEDVVVAHKTGDLDK-LEHDVGIVYHELGN-YIICILTKN -LD-TNKNGREVIGKISKLVYENf ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2XAU8_9FIRM --------FATWLDAAPGRYGVFALNLVNGKSV-SYHEKDVFPSASTIKVPIMIEVFRRVE -EDHLSLDSLLTLRAEDQVGGSGILFDLTPGSYSLRDLTTLMITVSDNTATNLLIDYL-GV -DAVNATMRRLGAHDTVLERRLQRVPVE--RPTVNRTTPYDLALMMERLAKGECVSLAVSE -RMVSLLKQCQG-PISITAGQPPTVTVAHKTGSLSN-ANHDAGIVYSHDGLAYVAAIMSEG -APHD--TLAPVLRRIGRA----- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus xylanilyticus TaxID=582475 RepID=UPI00083C9188 -----ERTIKQMLQETTYKVHMFVKEPKTEQFFmNERLEEVFQSASLIKVPILLAVLNNLE -SNNKSLEQEMKIAPEEWVDFSVISEQHLEQ-STIYELLVWMIITSDNTATNVLIDFL-GM -DVLNQYFREIGLLHTTIQRKMMDFER-LAKGFDNTTSARDMAHLFLRIYRRDLLSPAFSE -LTLDILSRQRV-HESLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNFGD-YLIGVFITE -VTN-NDQARQLIGRISKVVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A355F341_9BACT ----LPGQVERIAKQSRGVVSVAYENLGTGASL-AFQDSEILHAASTMKVPVMMALFEAVD -RGQMRLDAPVRVVNDSIVDGSRYAYAALGQTRTLEELIRRMIVRSSNLATNLLIDQI-GA -SNVTDLMRRLGAYDVTVLRGVEDSK-AFDAGLNNRVSARDLLLLYKKLLDDTTFSRASRE -RMLAILKAQEF-NEKIPAGLPPGTEVAHKTGDIT-AFHHDAAIVFPPGEKPYLLIVLTGG -IA-DEAVADRVIADVSRAVWTY- ->[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium amurskyense TaxID=320787 RepID=A0A0H4PHL8_9BACT --------------------SYIIQD-KEGNVLsKLNADKKIPSASIIKIPLLIYFMQNVE -EGKVKLSDSYQLKEADKVGGSGKLQYKPTAYATYEYLAKEMIRVSDNTATNILIRKL-GL -QQFQEWLRENGYKTTQLNRFMMDFE-AIALGQQNYLSAEEMNRLLLGLLNGQLLNKASAY -QAIEWLKNCED-DNALPHLLPDGIAVAHKTGTLEY-VRGDAGILYGE--KTIVLTVMVEH -FS-NVANADKIIAEIGRLAYQEf ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus borstelensis AK1 TaxID=1300222 RepID=M8D3H0_9BACL ---SLENALSTLLEKSGGQWGIYLEDLQTNEIW-GKGHDDRFYAASVIKVPIMAAVFAEAY -AGKFALEDKLTLRQEDQVGGAGILQHMTPGTWSIYDLTTLMIIQSDNTATNMLIDLV-GA -EAIRSVMNKTGMVNSQFHNKLMIVPAELEG--YNEVTAADLGSHLRHLATGKIISYNSCL -HMINIMKRQQH-RDRIPYHLPPKWELANKTGTVTR-TTHDIGVMYIGNRA-VTICLLSKN -IE--TVAANDVMAQIGRMVYDLy ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter immobilis TaxID=1348778 RepID=A0A3M9N4E7_9BACT ---SLREEVLQELRQQKGTFAVAFKDLQTDEEL-LLNEHESFHAASTMKTPVLIEAYRQAH -QGRFSLSDSLLVKNESIVDGSPFSYKVLGQKRPLSELLYKMIIQSSNLATNLVIEQL-DA -RKVTQTMRELGAKNMQVLRGVEDGK-AYQQGLNNTTTAYDLMVLFQQMARGKTVSPAASQ -EMIRILLDQKF-KDVIPAKLPKEVKVAHKTGWITK-VRHDSGIVFLPDGRKYVLVLLSKD -WDND-SAATAAMANVSQMIYRH- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YZ86_9BACL ---SLSTSIADLLQEAGGEWGIYLENLQSGEKF-ALNENQRFYAASVIKVPIMTAVFAEAY -AGKLALEDKIKLRREDLVGGAGVLQHLTPGTLTVQDLVTLMIIQSDNTATNMMIDLV-GT -EAIRTAMSKTEMVNSQFYNKLMVVPAELEG--YNEITAADMGSHLRYLATGKVISYDSCL -KMIHILKQQQH-RDRIPSLLPPKWEFASKTGSVTN-ITHDVGILYVGGHA-VTISVLNKG -LK--QKAAADVMARIGSLVYGVy ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma oryzae TaxID=1469603 RepID=A0A2T0T0J8_9BACT -----------------VTVSLAVQSLTDSSVAmSVNAERPVPSASVIKLPIMVEVMEQVK -AGTLDLSEIHILTDSEKAGGDGVLKNYSHRSISYADLLRLMLVYSDNTATNIFINEL-GM -AAINARIRAMGLTGTRLNRVMMDTVAA-RQGRDNYVTAADMNRLLSQLYRHRLATPALCE -QMLDILKQNED-TLTIPRLLPKSVVVAHKTGTLAY-VRADAGIVYA--RQPFLLTVLIQG -AP--TPDAERIIAELALICYNAf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517I7U7_BREBE ----LFAQISSLTKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIQLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GA -ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAADVMAQIGNLVYHVy ->[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus californiensis TaxID=161536 RepID=UPI00064DFCEF ---ELGDRIQRITDQSTGTWGISLYDLDTNETW-EMNEHHLFYAASVIKVPIMIAAFAANK -RGEFILSDTVELKRENIVGGSGVLQHLTPGTFTIYDLLTLMIIQSDNTATNMMIELV-GV -PSIQQTMKDIGLEKSKFYHKMMTMDVD--REGMNEITASEMAGMLRKLATGKIISVHACE -QMIAIMKQQQI-TNCLPGKVPKEWEIANKTGNVS-GIRHDIGIFYVGKRK-LIASVLTSG -LD--DIQSPDILSKVGLEIYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium lianum TaxID=388280 RepID=A0A1M7QG25_9BACT ---DLEAAIQDIVEDTAGDFAVAFKLLDSGLQV-LIHEKEVFHAASTMKTPVMIEIFRQVH -AGKMALEDSVLILNESIVDGSPYSYGRVGQQATVYELMYQMIIKSSNLATNILIEKV-GA -ENVTKTMRDLGAADIQVLRGVEDLKA-FDAGLSNTTTALDMMLIMEAIATGEAVGQEESR -QMMDILYDQYY-KDLIPKLLPDEVKIAHKTGSIT-GVQHDAAILTLPGGTSYVLVILSKN -LS-DVAAGKKAINEISKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0011AAB929 -----ENQIQDLIQKTPYNVHLFVKDPKTEQFLfSHQIEESFSSASIIKVPILLAVLAYIE -KHNISLHSPLTISPADWVDFSVISEQHLTQ-STVYELLVWMIITSDNTATNVLIDAV-GM -EFLNDYFHQIGLQETLLQRKMMDVER-LAMGIDNFTTARDMAHLFTRIHQQDLLASPYNR -LVIEILSRQRV-HEGLKRYLVDEVKLAHKTGGLDT-VNHDVGIVYSSSID-YMIGVFITN -VT-DNDLARQLIGRLSKVVYDH- ->[subseq from] Serine hydrolase n=1 Tax=Vitiosangium sp. GDMCC 1.1324 TaxID=2138576 RepID=A0A2T4VVJ5_9DELT ----LRADLQAIAQVKGASVAVAYQQLGDAKDSlYLEADRSFHAASTMKVPVMIELFRQAD -AGKLALDQQVPLVNQSIVDGSPYAYERLGKPVPVRELVERMITRSSNLATNTVIALV-DP -KRVTKTLRSLGATTMTVLRGVEDGK-AYEKGLNNTTTARDLATLMAAIERGQVASPDSTK -AMRSILLAQEL-NQEIPAGLPPGTPVAHKTGQIS-GVLHDAAIIYPSGRPPYILVVLTSG -IP-DEKVARSLIVDLSRRVYSH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A345GSJ2_KLEPN ------------------------------------------------------------- -------------------------EKNLADGMTVGELCAAAITMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVA------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI00119F9958 ---SLQKIIESYVTNIEADFGIYIKHLETNEEV-NIQGDKLFQTASVMKLPVLATLYEKAY -KGEINLQQRIQLTEQDYVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLATDKLLKILGGV -NPVKETMDRLGLKNIYIKHSIWELLSYQHNKESNVSSAKDMSLLLELFAKGEFVSTKCSR -EIIDILHRQHY-QQRIGGLLPRNTPVANKTGSLG-AMYNDAGVVYLPDKGQYVICVFSNG -HSLE-YEGDEPIAQISKIAYEYf ->[subseq from] serine hydrolase n=1 Tax=Marinobacter fonticola TaxID=2603215 RepID=UPI0011E7D310 ------------------------------------------------------------- -----------------------------------------------------------GD -ARVNALAKVLGVSRNEFAQTLDEAFAIYYHTGLNSGRLSAYSRFLEKLVNGDLLEKESQA -YLLNTMERIKTGDNRIVAGLPPDVSFAHKTGTQYR-RACNIGIATHGDGQRVIIAVCARG -TR-NLTDTERAMRQVGEAIT--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacteroidales bacterium TaxID=2030927 RepID=A0A316MI51_9BACT --kSMEQQISEYIDGKDARIGVAVI-VDGADTI-AVNGTKDFPMLSVYKFPQAITVADYCT -RNAIELSDIIDILPSELSEWSPLRDKYGVTRLPVNELLAYTLQQSDNNACDILFRLAGGP -LAADSLMKSMGYPDINVASTEDEMHRDTDLCYLNHSTPLEMSRLVDRFYRDLSHSSPECA -EIARLMESCSTGADRLAKPLARGVTIGHKTGTGDRNGVNDVGYIKIPGGRSYSISVFIAD -SAYDIAGTSAIIADISEIVF--- ->[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC665 TaxID=2711216 RepID=UPI0013EC5F19 ---------------SGAVVEIALHDLETGRAH-LIRADEPIHPASTMKVPVMLEAYRQAE -AGLIKLDDQLEIKNQSLVDGSPYTYKRIGGKAAVRELVLLMITESSNLATNILIEKL-GA -VNVTNFMKKLDAGDLKVLRGVEDDK-AFAAGMNNVGTARGLMTILTRLAEGTAVSKTADA -AMMDVLRAQKF-NDGIPAGLPKGTVVAHKTGSITN-VYHDAAVVEPPGRKPFVLVVMTRG -IEAD-HAARKVVAEIARAAYEE- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter immobilis TaxID=1348778 RepID=A0A3M9N2D2_9BACT --qKTEQQLKEILEASPALTGLVAVDLTSGETI-SFNPNVVFPQASAIKVPILLEVYQQAQ -AGKFKLTDLRAIAPENRVGGTGIIKDLPDTTFSIRNLAVLMIALSDNTATNTLLDLV-SM -ASINATMQRLGLKQTRVQRKMIQAAAS-GRGEENISTPAEAAKMLQLLYKGEFLNKAASA -EIISILQKTNRETSRLAAGLPASVPLAFKPGVLN-GVSTEWALVLLPER-PYAVAIMENY -KVP--GKAERVLEDVSAVLYQYy ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. FJAT-14222 TaxID=1932366 RepID=A0A0M9WWF8_9BACI -----KQTITEILQNAPYKVHMFVKDCKTEQFFiSEKLEDAFSSASLIKVPILLAVLNYLE -SNNKSIEQEIKIAPEEWGDFSVISEQHLEQ-CTIYELLVWMIIKSDNTATNVLIDFL-GM -EALNQYFRQIGLLQTTIQRKMMDFER-LAKDLDNTTSARDMALLFSRIYRKDLLSSAFSE -LTLDILSRQRV-HESLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYNNSRD-YLIGVFVTE -VTNN-DDARQLIGRLSKVVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Pontibacter sp. S10-8 TaxID=1797110 RepID=A0A1Q5PIL8_9BACT ---ALRQQITEELEKQEGTFAVAFKDMATGEEL-LLNERESFHAASTMKTPVLIEAYKQAA -AGKLSLSDSILVRNGSIMDGSMYSYTFVGQKRPVSELLYKMIIQSSNLATNLMIEEL-DA -KQVTQTMRELGAQDIQVLRGVEDSK-AYEQGLNNTTTAYDLMLIFEQIATGKAVNPEASQ -EMIRILLDQRH-REIIPARLPKEVKVAHKTGWIT-GVRHDSGIVILPDGQKYVLVLLSKD -LK-DEKAGMEAMAKVSELVYKY- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0008536A7D ----LFAQISSLIKDAGGEWGIFFEDLRTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIQLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNIMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAADVMAQIGNLVYHVy ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A317J2Q5_9BACT ---DLKSRIEDSLKTQSGIFALAFKDLSSNKTI-FINEHTIFHAASTMKTPVLVEVYNQVN -QHKISLNDSIVLKNESIADGSPFTYTHLGEKRSLSQLLYQMITVSSNFSTNLVIDRV-GA -NNVTETMRKLGLRDLQVLRGVED-NKAYAKGLNNIVTAYDLMILFEKIAKGKAVNPASSK -EMIKILEDQKF-NEIIPAQLPANVKVAHKTGSFK-GVHHDSGIVFLPNGKKYVIVILSKD -LT-DEEAATRMMAGISGMIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Nostoc sp. 'Peltigera membranacea cyanobiont' 232 TaxID=2014531 RepID=A0A235IY81_9NOSO ---ELKSQVKALMAHYSLKPGMFFLDIETGNYL-NIDGEKVFPAASTIKYPILIALFEQVD -AGNIKLDEKLVMRRDLVASGSGDLQKRAGIKLSVMETVNKMITISDNTASNMIIDRLGGK -AKLNQRFHTWGLKNTVIRNMLGDFKGT------NTTSPADLVRLSALVDQHKLISESSQF -QVLDVLRHCHN-NKLLAAGVGKGGSIAHKTGDIGF-LVGDAGIISLPNGKHYLAGIFVIR -PH-DDERGREFVRQVSRIVYQY- ->[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4U6CXY2_9BACT ---DLKQKISTELSKHKGSYAVALKDLTTGEEL-SINELQTFHAASTMKMPVMIEVFKQAS -QGKFKLTDSITIKNESIVDGSSYSYRHIGEKRAIKDLVYEMIIVSSNFATNMVIDLV-GA -KNVTQTMRDLGAKDILILRGVEDAK-AFQKGLNNTTNAYDLRLLFEKMALGKIVSQKACD -AMIKILLDQKF-NDVIPGNLPKDVKVAHKTGGLPN-IQHDSGIVFLPDGRKYVLVILSRD -WE-NEAANRKMLAGISEMIY--- ->[subseq from] class A beta-lactamase n=1 Tax=Paramuribaculum intestinale TaxID=2094151 RepID=UPI0013751C65 ---EMEVSLKTYVHDKDARIGVAVI-INGKDTV-SVNGKRDFPMLSVYKFPQALAVADYCH -KHNISLNDTIRISADDLNPWSPMRDKYGRKDLPLSEILAYSVQQSDNNACDVLFRLIGGP -QVADSLMKCLGYDEIHILNTEDEMYRDPYLCYANRATPLQMASLFDQFYRREMRHDSRLE -ALGAMMMSCNTGNNRLPLPLPTNAMVGHKTGTGGQGGVNDAGYVFLPNKQGYAIAVFVAD -SGYDMAETENIIADISEIVFQ-- ->[subseq from] Uncharacterized protein n=1 Tax=archaeon TaxID=1906665 RepID=A0A6A8ATQ9_9ARCH ----------AAAEEFDGVMGVSIKDLTTGDAL-SVNGDEQFLAASSIKIPILIELYKKAR -VGTLDLGKEVTVPDDVKVGGTGVIKELGNVTLTLQDLITLMITVSDNTATNMLIDVA-VM -DDVNATMKELGLNVTRLRRKMQDYE-AIAQGKENYSTPNEFTRLMEILHTSERLDPWIAE -QALAVLKKPKT--TTINRLLPYDVEIASKYGNMRN-SYCDVALVYHPQN-PYIITVMTKY -IPTDDVRKQDAISEVSKTAYDHf ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=UPI0002FA16BF --nKLRDAIKNIVDESPASISVTFCDLDEGEKF-SINGNKKSPSASMIKLLIMLTLLKKVE -LGEIDLNEKIKLEEENKVDGSGVLKELSCEHFSIRELLTLMVIISDNFATNILIDKV-GM -DDVNKLGRELNLLETSLERKMMDVGAK-EKGNDNYTSSEDVASILKMIYEKSFLSEEMSS -LAIDILLRQQE-RDRLQRYLPENLKIASKSGDLDN-LENDGGIFFTEAK-NYILVVLASG -AE-SNVAAKDIIGKISLEIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8CEU5_9BACT ---KFEQRLQQISSRVDGVVGYSVLDLTSGDRI-AHLERETFPTASTIKLAIVYELFRQAA -EGRIRLDDTIALDRAKAVGGTGVLSQLGTPTLSVREYATLMVIVSDNTATNVLIDRL-GM -QNISARMQSLGLGATKLRRHMMDTAAARRG-DENVSTPDDIVRLLQAIEKDE---PDASA -----LLKKPK--ESRLRRALPPGVEAADKPGELD-GVRVDAGIVFAKNR-PYALCVMAAF -LT-SEVEGERAIEEMSRAAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium hwasookii ChDC F300 TaxID=1307444 RepID=A0A0S2ZH51_9FUSO --tEWKKEIEKIISQVDGKVCVNFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKIS -EDKFSLSDTIMMANFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ -LMLEILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLEEK-VYILVVLTSR -MS--NLQCKQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas oligophenolica TaxID=301154 RepID=A0A502C1D9_9SPHN ---DLLNAIQALGTVFHGRVAITVRDIDEGWAV-AYHGDTLFPQQSVSKLWVAIAVMEAID -RGTLSLADPVTVRRSDLTVHQPIRPLVGKNGTTIAKLLEGAMTHSDNTCNDVLLWKVGGP -PAIRRMLQRKGIKDVGFGPGERILQARYLAAPYDGASANGVTLGLALLNRNALLSRRSTA -YLLSRMRASKTGPLRLRSGLRSGWTLAHKTGTGQSTGYNNVGILRSPNGHYYAVAVMIAS -TRRPIPARMRFMGNVTRAVIR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RDB7_9BACT --kKLEMRVEEIADRLDGVMGVAILDLTDGRIL-LRNADRVFPTASSIKIAILLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSQIMAGLTPSVVTNRDLAQFMVAVSDNAAANILIDRV-GK -DNVNTMLRGLGLTKTMLRRKMMDIAAARRGD-ESIATPQEMLRLLEAISKGKVLDKQSAA -EFIKQLSTRK--DSYIPRLLPESVQVANKPGELE-AVRNDCGIVFAPNR-PFAISVMTAY -DH-DERAAGNAISEVALEAYRYf ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0002137E02 --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLKQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENNGGIIWIEDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Candidatus Melainabacteria TaxID=1897007 RepID=A0A1F6SGB2_9BACT ---RLTNRLKYLAKQYSLEPGIFIWDFSTGQYV-DINADQEFPTASIVKIPILLQLFRRAE -LGFANLNDRMSLAEYNITGGSGYLQYKPVGTFPIHHLARLMIQESDNTATNMILSTVGGI -NELNRVLRSWGFSKTHMSDLLPDLYGT------NVSTPKDMGTMLFNLDNSDFLTLKSRA -AIVDIMSHVRN-RFLIQAGLPDNAQFIHKSGDIGT-MLGDAGIVMLPDGRKYIIVIMVKR -PW-NLYSAKEFIINASKITYNSy ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WOR-1 bacterium RIFOXYB2_FULL_48_7 TaxID=1802583 RepID=A0A1F4TKC6_9BACT ---ALQAKLNHQLAPFKHKVGVAFIDLKTGDIL-QVNGSMEFPAASVAKVPVMAAAYHLVE -LKQLNLAEKLKLRKEDKVGGSGYLQWMKPGTMSLKDLIGLMIMRSDNTATKMLVDRI-GL -GNINQYLQANDIKNTVLNDHTMLVE--PPSNNNNRTCPLDMAYLTLKIQESYGFDKDSSQ -EMLYFMKNQRY-RWGIWRGVPPGTIVADKTGNLT-GILNDVGVVYTKAGN-YVLAIFTRN -FPK-KREGRKIINDVSRLVYEEy ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00046A831B -----ENQIQDLIQKTPYDVHLFVKDPKTEQFLfSHQIEESFSSASIIKVPILLAVLAYIE -KHNISLHSPLTISPADWVDFSVISEQHLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -EFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIHQQDLLASPYNR -LVIDILSRQRV-HEGLKRYLVDEVKLAHKTGGLDT-VNHDVGIVYSSSID-YMIGVFITN -VT-DNDLARQLIGRLSKVVYDH- ->[subseq from] hypothetical protein n=1 Tax=Kallotenue sp. CFH 73958 TaxID=2592335 RepID=UPI00128BD248 -------QAREAVEDYPGVAGFYAIDLKSGGGY-GVRPDEIFFSASTIKIPVMVAVYRRID -QGKLKYSDSIVTKEEDWAAGAGWLRWTPGAKTTVEDALWLMMTQSDNVATNALTRIVGGP -GYVNEVARSLGAKDTHLFWRLSSERAA-VPSLDNRTTPRDMAKMMQEISAGRAASEFACR -EMIGLMEQNSL-EYWIESGVPQNVKVANKGGWLD-ATYNDVGLIEYEER-PYALAILTKY -APEEMAEGQTVLTNVSKAVW--- ->[subseq from] Class A beta-lactamase n=3 Tax=Muribaculaceae TaxID=2005473 RepID=A0A2V1IW38_9BACT ---EMEVSLKTYVHDKDARIGVAVI-INGKDTV-SVNGKRDFPMLSVYKFPQALAVADYCH -KHNISLNDTIRISADDLNPWSPMRDKYGRKDLPLSEILAYSVQQSDNNACDVLFRLIGGP -QVADSLMKCLGYDEIHILNTEDEMYRDPYLCYANRATPLQMASLFDQFYRREMRHDSRLE -ALGAMMMSCNTGNNRLPLPLPTNAMVGHKTGTGGQGGVNDAGYVFLPNKQGYAIAVFVAD -SGYDMAETENIIADISEIVFQ-- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter sp. HI0063 TaxID=1822240 RepID=A0A165QX19_9SPHN --sDLTRRIARLADASQGRIGVYAIDLSSGEEV-GVMADQWFPLASTSKVAIAATYLAGVD -QGKWTLSSEWRLPG------------RGGATLPARRHLELMISKSCNDCTDALLDAVGGP -AAVNRWMREAGLTEFMLTRDIATLIRATSIDVNDSATPRAMGQLLAGIYQGKWLSSSSRS -VLMSAMFATTTGKNRMSAALPGSANLAHKTGTLSR-TASDIGLFQTADGRTIAAAIYVTG -QSPSMAYEN-------------- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium hwasookii ChDC F128 TaxID=1216362 RepID=J8VHG0_9FUSO ---ELKKEIEKIISQVDGKVCVNFYDLNKNNGF-SINGSEKVLSASMIKLLILAELMKKIS -EDKFSLSDTIMMANFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ -LMLDILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWFEDK-VYILVVLTSR -MS--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Caenibacillus caldisaponilyticus TaxID=1674942 RepID=UPI00098876E2 --qQLIQQIEQHVQEAGGTWGIAIEDLNRGETW-RLNGDQPFYAASIIKLPIMAAVYAAAA -RGDFRLSDFLTLKQDDLVGGSGVLQHLTPGILPIADYVMLMIIQSDNTATNMLIDLV-GT -EEIQKAMKALGMENSTFYNKLMTVPVDTPG--RNMITAADVTKLLSTIARGRFVSWYACE -QMIAIMKKQQW-RDGLPAFLPDEWEVANKTGWMT-GIRHDAAIFYVGRR-TLAVTTLSKD -C--DDWAARVAMAKIGKAIYEY- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D89CE3 ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFAFEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMKNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL -KMVTILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHAy ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q8AIM2_9BACT -------------KTSGADVAVAFRTLDGRDEL-LIQPDVDYHAASTMKVPVMIELFRQAR -AGTLKLDDQMPVVNESIVDGSPFAYKRIGSRMSYRDLLDAMITVSSNFATNLIIEHL-GP -KNIQRTTDALGATGMHVLRGVED-NKAFAKGLNNTTTARALLTLMEKIAKGDAVDKASSD -EMVAVLKRQTF-IDRIPAGLPPGTPVAHKTGEITK-IQHDAAIVYAP--RPFALVILVRG -LQ-DAKEGSKLAAEITRVLYD-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Acidobacteria (miscellaneous) TaxID=305072 RepID=A0A1Q7MQ53_9BACT -------------KTSGADVAVAFRTLDGRDEL-LIQPDVDYHAASTMKVPVMIELFRQAR -AGTLKLDDQMPVVNESIVDGSPFAYKRIGSRMSYRDLLDAMITVSSNFATNLIIEHL-GP -KNIQRTTDALGATGMHVLRGVED-NKAFAKGLNNTTTARALLTLMEKIAKGDAVDKASSD -EMVAVLKRQTF-IDRIPAGLPPGTPVAHKTGEITK-IQHDAAIVYAP--RPFALVILVRG -LQ-DAKEGSKLAAEITRVLYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Azospirillum sp. 51_20 TaxID=1896972 RepID=A0A1Q6UAG7_9PROT ---SLAYRLNRLAAGKDCRVGAAVIA---GSHS-FVHGEGKYPLLSVFKLFIAAQVLDKLG -RENTDCKTELTITRDMIDEYSPMRDERRTYPISVARLLEYMVAESDNNAADILLAYAGGA -EQTQAYLNRLGFGGIDVSVSEKEMNADIAKQYVNRASPADVVRFLKTVREGDILTPENRK -FFDKIMTATVTGGDKLKAGLLQGTVFGHKTGSSSRTADNDAGFVILPDGRTYYIAVMVSD -SRMSDRENAALAAEISAVVYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_12_FULL_39_28 TaxID=1797951 RepID=A0A1F9V9Q5_9BACT --eELKRKIRYQIDHFPGVVGIYIKDLNRGWTI-EVQAEKLFPSASLVKIPIMATLFQAED -QGLISLEDTLALKKKFKTSGSGSLKKRIGTRYTLRALINKMITLSDNTATNMLTDLL-GL -SYYNSSFSQLGLKNTNFSRKIMDLNKR-DQGIENYTTPKDMGLILEMIYNKKL---KNSE -EMLEILKDQKI-NDRLPVSIPSYWPVGHKTGLMRE-CCHDVGIVFAPSST-YIVCVLTQD -IR-RIRRAKSFISEIGHLTALYy ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UZR3_9BACI ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFAFEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMKNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL -KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHAy ->[subseq from] serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012950808 --hALEARLAELDRRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVD -KGVGKLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MD12_9BACI ----LFAQISSLTKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL -KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYVGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHVy ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A524HVL2_9BACT ---ALAEALSEPIAASDAEVGVYFRNLGTGDTV-LINADLRLHAASTMKVPVMIQLFRDAE -AGRFDIDQPVPIGMTSIADGSLYDYQKVGSAVPARELIDLMITRSSNLATNILIELA-DA -RRVTATMRSLGADSIEVLRGVEDLKA-YRAGLSNTTTARDLGVILTALAEGRAAGESATA -DMLAILEHQEF-NEGIPAGLPAGTRVAHKTGWIT-AIDHDAAIVYPDGGPPYVLVVLVRG -IE-DHAVSSKLIATLSGITYR-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D10CFAB ----LFAQISNLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSLLNKG -LE--QKDAANVMAQIGTLVYHVy ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127ST58_9BACT ------AAVEKITDGAGADVGVAYA---SSEKY-RQNGSRQYPLLSVFKLHVAVAVLDKAD -RENIALDSRIQIPSAEIKPYSPLREKYGVCDLPLRELLRYMVAESDNNACDILIRWLGGV -KKVAAYSRKIGLRQTEILVTETEMNRNVRWQYANKAPLSEIIRLLQLIDGGKLFAPELHK -ELLAIMEKTSTGTDKIKKYLPSFVSVAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD -SRLSDKENAEIIARIAFLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus vulpis TaxID=2325572 RepID=A0A544TUZ3_9BACI ---TLQQKIESYIRDIDATFGIYIKHLGTQEEV-NIEGNRLFQMASVFKVPILATLYEKVY -KGEIDLHERVKLLEEDFVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLATDKVMSIVGGA -NSVQEKMHQIGLNNIYIKHTCWELLSFQESTDNNVSSAKDMSLLLEKIALGEFVSTECSR -EIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDAGIVYLPNKGEFVITVYSTG -GSLE-YKGDEPIAHIAEIAYQYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacter sp. RRmetagenome_bin22 TaxID=2599629 RepID=A0A2W5Z637_9BACT ---RLAPQLMRLASGTRGVVAVSVVDLDSGMSI-AINGDRNLPAASTIKVPVMVEVLRQID -VGKFSFQRTVSLTDADRDCYGSLCTAHWGSQYTVLQLVWTMITVSDNTATNMLIRLV-GR -QHINQTMSGLGLDQTRLGDVIRS-----DGDIRLRTSANDMMRLLGMIAGHRLINAQACD -EMLQILSGQRH-NRLLPAWLPKGLTIAHKTGTLRD-TLNDVGIVELD-GAPYVICVMTTH -LA-DLDAGERFIRRASLLTYRAf ->[subseq from] Uncharacterized protein n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A359LZN7_9BACT ---KTLARISEVDAKLDGALGVAAIDLTSGRVL-SYNANSVFPQASSIKIPILIRLFRDAR -AKQVNLDEKITLTERDMVGGSGHLRGLIQKGLTVREVATAMMETSDNTATNKIIAMV-QR -ERVNQLLDELGFANTRLRRIMMDTAAA-GRDEENVSTPLEMARLVEKIYRNEAAAPADCA -EIAGIMKKVKA---EMREAIPVGVDVASKPGGVP-GVAAETGIVYLANR-PFVLSVMSTF -LAP----KTHPVGEVTRAVYSHf ->[subseq from] Beta-lactamase n=1 Tax=Planctomycetes bacterium ETA_A1 TaxID=2528023 RepID=A0A517XUI6_9BACT ---ELADTLAPLLKAHRGRVAVAVKHLKTGAEF-YHQADEPMPTASLIKFPVMVEAFYQAA -DKKIDFGTTLTLKKEHRVPGSGVLTSHFSDGFPLRDAVRLMIAVSDNTATNLVLEQT-GI -RPVNERMAKLGLTETRINAQVFRGSTRTKKYGLGSTTAREMVKLLEMLQENKLVSEEACK -AMIAHLRACDD-TAMFKRYLPPGVLLAHKTGAVSN-ARTQAGIMTLPSG-PVALCVLTNE -NADQDNAAQVLLANVAKAVYDHf ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. TH156 TaxID=2067454 RepID=A0A2N4XGY5_9BACT ---QLKNAILARLNPVEGEFALAFKDLQTGQTV-FINEKESFHAASTMKTPVMIEIFKQAK -AGKFKLTDSILVKNESTVDGSPFKYKKTGQQMTIYDLTYQMIIVSSNLATNILIDLV-GA -KNANATMRALGANDIQVLRGVEDSK-AFQSGMNNTVTAYDLMLIFEKLALGEVVSRKDSE -AMIKILLDQKF-NEIIPARLPGAAKVAHKTGSIT-GVQNDSGIIYLPDGRKYVLVILSRK -LT-DVKKGVEALADVSGMIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. animalis 7_1 TaxID=457405 RepID=A0A140PSV4_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSDHFTLKELATLMIIVSDNQATNILIDFL-GM -KNINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus arenosus TaxID=1229153 RepID=A0A3D8Q206_9BACI --eQLRQHIKRIIKQSGGKWGISIEELGTNNSW-GINEGDLFYAASIIKIPIMTAVFNDYE -NGRLSLSNTLELKREEMVGGSGVLQHSPGTKWTIYDLLTLMIIQSDNTATNMLIDVI-GM -ESIQQMMKDIGMQDSKFYNKLMTVPATIQG--YNQVTAQELTMMMKKIAMGKIISMHACE -QMIAIMKKQQL-TDCLPAKLPPEWQLANKTGFTS-GVRHDIGILYVGDRA-MVATVLSQD -VD--DNRSKDAIAEMGLEIY--- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A502E085_9BURK ---HLLADLARIDASGKARIGVYVRDLDTGRAI-SYKADQRWYLASMVKVPVAMAVLRGIE -RGDYTLDTEVTLRASDYVDGAGSTNRQPVGQIAIRVLLEQMIIYSDNTASDMLIDLV-GI -AEVNALVASLVPEGFRRITSLGAIRRAYYATGLNSGRLDAYGELMSLLVGGKALSPLSTS -YLLKLMERVATGTNRIKAGLPTGVRFAHKTGTQRR-RTCDAGLVRTNNGQRRVLVVACTR -DEPSLERSEFALMQVGAAIC--- ->[subseq from] Serine hydrolase n=1 Tax=Snowella sp. TaxID=2164131 RepID=A0A2W7B5W6_9CYAN ----LKQKLANLDKKQKIETQAFFIDLDNGKYV-NLAGDTPISAASLIKIPIAIAFFQDVD -AGKIKLNEKLPMGKDVIASGSGDMQYQQGQKFTALETVTKMIAISDNTATNMLIKRMGGK -AVLDQRFQAWGLTHTQIHNLLPDLEGT------NMTSSKDLATVLLKVNQGELISLKSRD -RLLGIMQETKT-RTLLPPGLESGAIISHKTGDIGT-VLGDAGIIDMPSGKRYIQAIIAKR -PYND-IAARTLIQDMSRATYQH- ->[subseq from] Serine hydrolase n=2 Tax=Acidovorax sp. Root217 TaxID=1736492 RepID=A0A0Q8T5E3_9BURK ----LQAELTQVAAQNTAGIGVYVRDLESGIAV-SHRGQERWYLASTVKVPVALAVLQAVE -RGDFTLDTRLRVRASDYVDGAGHTNAKPVGALSIRYLLEQMVIYSDNTASDMLIGLV-GI -RAVNALVEQLVPRGFERITSLADVRRAYYASGLNSGRLDAYADLLELLVNGKVLHAAHTR -YLLSVMERVQTGVHRVQAGLPKTARFAHKTGTQR-ARTCDSGLVTVPGRDQRVIVVACTR -GELSSARSDRALRDVGAALC--- ->[subseq from] Serine hydrolase n=2 Tax=Fusobacterium TaxID=848 RepID=A0A2C6B447_FUSNP --tEWKKEIEKIISQVEGKICVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELLKKAS -ENKFSLSDTITITNFMKTEGDGVLKENIGHHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus xylanilyticus TaxID=582475 RepID=A0A0K9FE55_9BACI -----KQTITQILQKAPYKVHMFVKDCKTEHFYiSEKIEDTFSSASLIKVPILLAVLNYVE -NNNLSLEQEIMIAPEEWVDFSVISEQRLEL-STIYELLVWMIITSDNTATNVLIDFL-GM -DTLNQYFREIGLLQTTVQRKMMDFER-LAKGFDNTTSARDMALLFSRIYRRDLLSSAFSD -LTIDILSRQRV-HESLKRYLVDEVKLAHKTGGLDT-VDHDVGIVYSSSGD-YLIGVFITE -VTN-NDHARQLIGRISKVVYDY- ->[subseq from] serine hydrolase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI00119F6336 --qRLTESLARIDAAPDGRIGVYARDLASGDSV-SFRAEQSWYLASTVKVPVAIAVLRGIA -RGDYTLDTPVTLRADDYVDGAGSTNRHAVGALPIRFLLEQMVIHSDNTASDMLIGLV-GL -AQVNAVAAEVAPGGFGSITRLAEVRRAYYATGLNTSRLDAYGELLARLADGQLLPPAQTR -YLLGLMERVVTGPQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAGGT-RVLVVACTR -GELSLVRAERALREVGTALC--- ->[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SGM8_9BACT ------AAVEKIADGAGADVGVAYA---SSEKY-RQNGSRQYPLLSVFKLHVAVAVLDRAD -RENIALDSRIQIPSAEIKPYSPLREKYGVRDLPLRELLRYMVAESDNNACDILIRWLGGV -KKVAAYSRKIGLRQTEILVTETEMNRNVRLQYANKAPLSEIIRLLQLIDGGKLFAPELHK -ELLAIMEKTSTGTDKIKKYLPSFVSMAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD -SRLSDKENAEIIARIAFLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas populi TaxID=2484750 RepID=A0A4Q6XT84_9SPHN ---ALLNAVQALGAAFHGKVAISVRDVEQGWMV-AWNGERANPQQSVSKLWVAITVFDAID -HRRLSLTTPVTVRRADLTVHQPILPLVGPDGTTVGALLQCALTRSDNTCNDVLLWKVGGP -AAIRRMLTEKGIRGVGFGPGERVLQARYLAAPYDGATANGVTLGLSLLGQRKLLSPASTQ -RLLSIMLASKTGPLRLKSGLRTGWRMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPISARMRLMGNVTRAIIR-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4ICZ4_9BACT ---QMEDSVRLIAKGTDAVVGVAILDLTDRRAF-YLNADAVYPTASTIKLAVLAELYRQHA -RAGATLGDLYTIDGKDVVGGSDIMGGLTAGIVTNRDLATMMMAVSDNAATNVLINRV-GM -DNVNGWLAGLGLKNTRLRRQMMDVQAA-QAGRENTATPRELVLMLEALHKGDILGAPLTD -EFFRMLGTGKM--SYLPRLLPAAVRTANKPGDLD-AVRNDAGIVFVPNR-PFAIAVMTTF -GR-DHREQEMAIARISRTAWSYf ->[subseq from] Uncharacterized protein n=1 Tax=Acetobacter sp. 46_36 TaxID=1896965 RepID=A0A1Q6T199_9PROT ------AAVEKIADGAGADVGVAYAS--SGK-Y-RQNGSRQYPLLSVFKLHVAVAVLDRAD -RENIALDSRIQILSAEIKPYSPLREKYGVRDLPLRELLRYMVAESDNNACDILIRWLGGV -KKVAAYSRKIGLRQTEILVTETEMNRNVRLQYANKAPLSEIIRLLQLIDGGKLFAPELHK -ELLAIMEKTSTGTDKIKKYLPSFVSVAHKTGSSSKIADNDVAIIKSGNN-VWYLAVMVAD -SRLSDKENAEIIARIAFLIYK-- ->[subseq from] serine hydrolase n=1 Tax=Erythrobacter pelagi TaxID=994320 RepID=UPI00132C6604 --sDLTRRIARLADASQGRIGVYAIDLSSGEEV-GVMADQWFPLASTSKVAIAATYLAGVD -EGKWTLSSEWRLPG------------RGGATMPARRHLELMISKSCNDCTDALLNAVGGP -AAVNRWMRGAGLTEFMLTRDIATLIRATSIDVNDSATPRAMGQLLAGIYQGKWLSSSSRS -VLMSAMFATTTGKNRMSAALPGSANLAHKTGTLSR-TASDIGLFQTADGRTIAAAIYVTG -QSPSMAYE--------------- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI00029CAC95 -----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLEASFSSASLIKVPILLALLSYIE -KNKLSLDSTLMISPADWVDFSVISEQRLTQ-STFYDLLVWMIITSDNTATNVLIDVV-GM -AYLNAYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLSPPYNK -LVIDILTRQRV-HDSLKRYLIEDVRLAHKTGGLDT-IDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Uncharacterized protein n=1 Tax=Psychrobacillus sp. FJAT-21963 TaxID=1712028 RepID=A0A0Q3TQU8_9BACI ---TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE -RREFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIMMLMIIQSDNTATNILIDLV-GI -DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE -QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE -E--DDLVSKRILSEIGEAIYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_54_10 TaxID=1797945 RepID=A0A1F9TYU0_9BACT --tELHQKINYQLRHFPGVAGIYVKDLKTGWTI-EHNSDDLFPSASLVKLPMMAVIYQAQV -SGRLSLDESITLMRNMKARGSGHLRKRPGTRYRVRELIFKMITESDNTATNMLTDRL-DL -DYYNRHFLALGLSRTNLSRMIMDLRRR-DEGIENYTTAKDMGNLLEMIYFKNLT---GSE -EMLDILKHQKI-NDRLALGIPNGWQIGHKTGLMNN-ACHDVGIVFSPTND-YVICVLTTQ -IR-NFRRPKNFISAVSHLVATYy ->[subseq from] Serine hydrolase n=2 Tax=unclassified Nostoc TaxID=2593658 RepID=A0A235HUC2_9NOSO ---ELKSQVRALMTHYSLKPGMFFLDIETGNYL-NIDGEKVFPAASTIKYPILIALFEQVD -AGNIKLDDKLVMRRDLVASGSGDLQKRAGIKLSVMETVNKMITISDNTASNMIIDRLGGK -AKLNQRFHTWGLKNTVIRNMLGDFKGT------NTTSPADLVRLSALVDQHKLISESSQF -QVLDVLRHCHN-NKLLAAGVGKGGSIAHKTGDIGF-LVGDAGIISLPNGKHYLAGIFVIR -PH-DDERGREFVRQVSRIVYQY- ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD69_9BACT ------------------------------------------------------------- -------------KKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Serine hydrolase n=1 Tax=Ammoniphilus sp. CFH 90114 TaxID=2493665 RepID=A0A4Q1SYB5_9BACL ---QLVDHVKELTESSGGVWGVVIEDLQTGEEF-RHNAEERFYAASIIKVPIMVAVFDAAN -EGKFHLSDTLALRREDMTSGAGVLQHMTAGTLSIYDLVTLMIIQSDNTATNMLIDLV-GK -KRIREVIKELELSGTVFFNKLQVIP--YPLKGSNQMTAGDAAQLMKRLVTQKVISWQACE -QMIEIMKKQQL-NDFLPSGMPPSWAFAHKTGMVTQ-IHHDVGVLYRNGRA-VLLSVFSRG -LE--TKEARQTMANIGLAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UT02_9BACT --------------ASGAEASVAFRTLDGKAEL-LVRPDVAYHAASTMKVPVMIELFAQAR -KGTLRLDDPLPVKNSSIVDGSPYSYRSVGGTLTLRQLCEAMITVSSNLAANLLIEKL-GV -ESIRRRVHKLGADGMELLRGVEDAKA-FRKGLNNTTTARALLVLLDRIALGKAVDAAASR -QMVDILGRQRF-NDAIPAGLPAGTPVAHKTGSITK-IHHDAAIVYGP--RPFVLVVLVRG -LE-DEKKSKALTADIARAMY--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MG91_BREBE ----LFAQISSLIKDACGEWGIFFEDLRTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRKEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAAEVMAQIGHLVYHVy ->[subseq from] Class A beta-lactamase n=1 Tax=Dethiosulfovibrio peptidovorans TaxID=47055 RepID=A0A2G6M623_9BACT ----------DRINSLSGTVGLVIEDLQGKNRK-EWNATELFPAASVIKLPILWELFSRVE -KKDFSLQDEVELLEEDKVEGFGILKEHAGLRLSLKDIATLMIVLSDNVATNMLIDLL-GM -DNINDTIESLGLKQTSLQRKMMDSEA-KDRGADNFTSPEDVALLLRHYLENAELSSFSRD -VMLDILLRQQC-NNKLPFRMPPGAPFAHKTGDLP-GTEHDVGILLFPEKT-LLVVVMTKD -LR-DNQKGIIFHNEIGELLYTTf ->[subseq from] Uncharacterized protein n=1 Tax=Psychrobacillus sp. FJAT-21963 TaxID=1712028 RepID=A0A0Q3W401_9BACI ---SLQQKIESYIENIDATFGIYIKHLGTNEEV-NIQENQLFQMASVCKVPILATLYEKVY -KGEIDLQERIKLVEEDYVPGSGVFQEMDYGVPTIKDLATMMIIVSDNLATDKVLSIVGGA -DRVQDRMHQLGLSNIYTKHTIWELLSFQDSTENNVSSAKDMSLLLEKIALGEFVSEECSS -DIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDTGIVYLPDKGEFVITVYSAG -SSLE-YKGDEPIARISEIAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y8U0_9BACL ----LFAQISSLTKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAQDMGSHLRYLATGKVISYDSCL -KMVVILKAQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-ITLSILNKG -LE--QKDAANVMAQIGNLVYHGy ->[subseq from] serine hydrolase n=1 Tax=Salinicola halophilus TaxID=184065 RepID=UPI0013A619F5 ------------------------------------------------------------- ------------------------------------------------------------P -ARLAAISRFIGVPVSDFQRDLSQAFDRYYETGLNAGRLDSVGRLLAMIERGETLSPASTQ -TLLAVMERTRTGANRLRRSWPDDVDFAHKTGTQRS-RFCDGGIASRDEGVRRVVVVTCAK -GTLSMAPAERAMRDVGAAVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus halotolerans TaxID=1368476 RepID=A0A3M8HBC4_9BACI ---YLQDRISRLIDEESFDVKVVVKDMDTDNILfEKGIYDVFSSASLIKVPILIAVLDYIE -QRDGLLYQELTITKGNCVDFSVITEQG-QTKSTLYELLVWMIITSDNTATNVLIDFV-GM -DNLNRYFKKIGLTETSVNRKMMDFIRM-EKGIDNVTTAKDMATLFTHIYRKTLLSETYSD -LAINILSRQRI-QDSLKRYFLNDVKMAHKTGSLDT-VEHDVGIVFHPSKN-YLIGVFVTN -HS-SNERAKQLIGRISQTVYQH- ->[subseq from] CARB-like beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=Q2PPY0_PSEAI ------------------------------------------------------------- --------------------------------ITLDDACFATMTTSDNAAANIILNALGGP -ESVTDFLRQIGDKETRLDRIEPELNEGKLGDLRDTTTPNAIVNTLNELLFGSTLSQDGQK -KLKYWMVNNQVTGNLLRSVLPEGWNIADRSGAGGFGARSITAVVWSEAQSPIIVSIYLAQ -TEASIADRNDAIVKIGRSIFEVy ->[subseq from] serine hydrolase n=1 Tax=Psychrobacillus sp. FJAT-21963 TaxID=1712028 RepID=UPI0009E9B9E9 ---TLVSRIQDLIDQSKGTWAIVLEDLSLGEKW-ELNGDELFYAASVIKVPIMAAVFNAVE -RREFSLSDQIVLKEEDYVGGSGILQHFTTGTLSIQDIMMLMIIQSDNTATNILIDLV-GI -DSVVQSMNEVGMEKSTFYNKLMMNNPNPK--GFNQISANDIAKLLKQMAIGELVSAKASE -QMINIMKKQQI-KDCLPEKLPTAWELAHKTGWIP-GTRHDVGIFFVGERK-LIATVLSEE -E--DDLVSKRILSEIGEAIYNY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Nostoc sp. NIES-2111 TaxID=1973475 RepID=A0A1Z4IH76_9NOSO ---QLDSQIKRLMKRYSLSPGMFFLDMETGEYL-DINGEKIFAAASTIKFPILIALFQEID -AGRISPNEILVMRRDLMTGGSGTMQYRKAGSFGLMETASKMMIISDNTATNMIIDRLGGK -NVLNQKFRRWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALISRKKLLSSKSNS -QVMSIMTRCSN-RSLLPVGLGKGAKIAHKTGTLGR-VLADAGIIQTPSGKRYLAGIMVAR -PFGD-ARARTFINEVSRLVYG-- ->[subseq from] Serine hydrolase n=1 Tax=Calditrichaeota bacterium TaxID=2212469 RepID=A0A3M1ADU0_9BACT -----SKYLKGLSDSLHAEISVSFYDLQTGQAY-GFADRKMMHAASTMKVPVMIEVFRQAE -AGRFSLHDSLLVKNQSIVDGSPFSYQVIGQKRPIRELVEQMITWSSNLATNLLIEWV-GA -KNVMATLREIGAKDMQVLRGVEDLKA-YRQGLNNRTNAHDLMVVMRALAQKTVASPAACK -QMIDILKHQHW-RTKIPGGLPPGVAVANKTGSIT-AIDHDCAIVFPPQRKPYVLVVLTRG -IA-DHDQAAATIAAISHKIYA-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium hwasookii ChDC F174 TaxID=1307442 RepID=A0A0S2ZL92_9FUSO ---EWKKEIEKIISQVDGKVCINFYDLNKNDGF-SINGDEKVLSASMIKLLILAELMKKVS -ENKFSLSDTIMMVNFMKTEGDGVLKELNTGHFNLKELATLMIIVSDNQATNILIDFL-GI -ENINLLGKELGLKETFLKRRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ -LMLDILLKQQQ-GERLQRYLPTDIKIAHKCGDLDN-LENDGGIIWLEDK-VYILVVLTSR -MS--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC4E99 ---SLSTSIGDLLREAGGEWGIYLEDLQTGEKF-TWNENQRFYAASVIKVPIMTAVFAQAY -AGKLALEDKIKLRHEDLVGGAGVLQHMTPGTLTVQDLVTLMIIQSDNTATNMMIDLV-GI -EAIRTAMSKTEMVNSQFYNKLMVVPAELEG--YNEITAADMGSHMRYLATGKVISYDSCL -KMIAILKQQQH-RDRIPFLLPPKWEFANKTGSVTN-ITHDVGILYVGSHA-VTISVLNKG -LK--QKTAADVMARIGSLVYGL- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas sp. WG TaxID=1592629 RepID=A0A0W1QGG1_9SPHN ---ALLNAVQALGAGFRGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HARMSLATPVKVIREDLTVHQPIRPLVGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLAQDELLSYGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGNVTRAIIR-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A497DZC0_9BACT ---ELVKTVTSIAQEIKGKVGVYVKHIESGETI-GYNENERFQLASVFKIPLLLTLFKQIH -LGKISLDDRLVLRTKDKTFGSGLLSSMKPGLLSINDLQLLMMAKSDNTATDILYEIV-TP -QAINEYMKELGLKSTKIDYNTRQLILQFDQSDHDTSTPYEIGLLLEKCVKGEIINKEISD -QIVETMKHH-TGAELITRYLPFGVTIARKGGSLAYTVLNDSGIVWLPYKGTLVICIFCNE -LNEVHYELKDKMGRIARAAFDYf ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SGAir0095 TaxID=2070463 RepID=A0A4P8S5G8_9BACI ------------GEQLNNNVKLIVNDARTNELLlSKDINDVFSSASLIKVPILLAVLDHLE -NQNQSISQMVKITPDNRVEFSVLTELE-AEEATLHELLVWMIIVSDNTATNVLIDLL-GF -EKLNQYFIKIGLGHTRIRRKMMDFVQ-LESGFDNTTTAKDMALLFTAIYRGELLSKKHSE -LVINILSRQRI-NDSLKRYIADDIKIAHKTGSLET-VEHDVGIVFTEKND-YIIGVFVTE -HTN-NEEAKQIIGKISRIIYGH- ->[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52909 TaxID=2653851 RepID=UPI00140D7462 ------GKLEDRVKGYDGVAGVYVRDLEGDFGY-GVRADETFFSASIIKVPVMVAVYRKVE -KGDLSFSQEVELKEEDWAAGAGWLQWEKAGTQTVGDLLLLMMTQSDNVATNALVRMVGGK -DHVNDVAESLGAKDTLLYQKVSSERGAVPA-LDNRTTPRDMATMMQKIADDEAASEKSCG -YMKDLMRTNEL-DWWLDAGLPADVDAANKAGWLYQ-VYGDVGIVEHEGN-RYAIAILSKH -GSATVDEGAVLIEDLSRTTWE-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides stercoris TaxID=46506 RepID=A0A3E4UL47_BACSE ---SLTDTISKIVSEYPGEIGVAVI-INSRDTI-TVNNKSIYPMMSVFKVHQALALCNDFD -SKRISLDTLIRINKGKLDPWSPMLKEHSEPELPIRKLLNYTLIQSDNNVSNLMFKRLLDI -AKTDSFVATIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTDKIISDEKQD -FIKNTLKECKTGTDRIAAPLKEGVVIAHKTGSGDNGAHNDVAFIRLPNNEYYTLAVFVKD -FKGNETQAAKVIARISETVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A2C6ATC1_FUSNP --tEWKKEIEKIISQVDGKVCVNFYDLNKIDGF-SINGNEKVLSASMIKLLILAELLKKAS -ENKFSLSDTITITNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=UPI00136F62F2 --sQIEERLKTYVAAQDTRIGVAVI-IDGKETI-SVNGNRDFPMLSVYKFPQALAVADYCM -KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP -QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDNPVHE -AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD -SAYDMARTEKIIADISKIVYQ-- ->[subseq from] serine hydrolase n=1 Tax=Solibacillus isronensis TaxID=412383 RepID=UPI0009A73C64 -----HKQLDRIIAQCPYKVHVIVEDYNTNEIVwKNRGEEIFSSASIIKVPILITILAHLQ -KTNSNLNHIYEIVPENMVEFSVITEQRQ-IRATLHELLLWMTITSDNTATNVCIDLL-GM -DAFNNYFKEIGLHNTRVQRKMMDFERQ-KLGFDNETTAEDMQHLFRQIYRGTLLTKEWNA -IALDILSRQRS-HESLKRYIVDDVKMAHKTGGLDT-VDHDTGIIFTKERD-YFIGVFITE -VT-DNEKARQLIGTISKIVYDHf ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A246EI18_FUSNP --tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGNEKVLSASMIKLLILAELLKKAS -ENKFSLSDTITITNFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGKA-YISVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6CYV9_9BACT --kKLEARVDEIAQRFDGVMGIAIVDLTDERAI-LKNADQVFPTASSIKIAILLELYRQEQ -QGKAKLDDTYTFDAKDVVDGSQIMTGLTSGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM -QNVNATLRNLGLTKTTLRRKMMDIAAA-KRGEENVSTPQEMTRLLEAIHKGKALDKELAN -AFMKQLSTKKE--SYIPRRLPPDVDVANKPGDLD-GVRTDSGIVFAKNR-LFAISVMTAY -DR-DERAAEGAIAEIALEAFHYf ->[subseq from] Beta-lactamase n=3 Tax=Acidaminococcus TaxID=904 RepID=G4Q6H0_ACIIR -----------------APYGVYFSDLKTGKGY--YRNSVQTPAASMIKVFILAAAYEDIR -DGKLSLTETFTLTDKNVVAGSGVLQGMPKGTVTVKKALDEMIIHSDNTATNLMIDRL-GM -DRVNRYLKEHGYKDTTLRRKMMDFDAA-KKGAENMTTVRDVGLLFKRLYQGKCVSKDLDA -QMLAIYKAQVD-TDMLPDKLPKGTVVAHKTGEVRD-LRHDGGIVYTAKGD-YVLVVFTRD -YTPY-----ASVADLSRRVYDG- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium MEL.A1 TaxID=1899017 RepID=A0A1D7YSX4_9BACT ----LESQLSNLAAMYSIHPSVYVWDYETGNYV-DMNADEIFPTASIIKLPVLVELFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFRAANSYTIDKLARMMITESDNSATNMLMARLGSM -TDINSALREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPKFLSNSSRE -KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR -PHN-SPLGKEFIVKASQVIYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Tissierella sp. P1 TaxID=1280483 RepID=A0A265Q247_9FIRM ----------------EEKVSIIIKDLTNDQWIlKYDENRTFPSASIIKILIMAEALERVE -KGEFDLEQKIKVRECDRVEYSLVSELKLE-EYPLIDLITLMIILSDNTATNILIELL-GY -ERINEMAKKIGCNDTILRRKMMDFEAA-KEGRENMTSPMDIAILMEKIYNKSIISPEMCE -LMIHILSRQKH-RNMLPRYILDEVVIAHKTGELS-GLNHDIGIFYLENI-HYLIGIFTTD -GK-DDLVGKGTIGKISKLVYDN- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8IYL0_9BACT ---ALRARVLSLIKASGAEVAVAFRTIDGRQEL-LIDPDTTFHAASTMKLPVMIELFRQAE -AGMLSLDDPLPIRNHSIVDGSEYPYKAIGGTLTLRQLAEAMITVSSNFAANLLIERL-GV -ENIRRTVTKIGADGMQVLRGVEDAK-AFEKGMNNTTTARGLLVLLEKLANGPVVSTKADA -DMIAMLSRQTF-NDAIPAGVPAGTRIAHKTGTITK-IHHDAAIVFAP--RPYVLVVLVRG -LQE-EKESAALIAAISREVW--- ->[subseq from] Beta-lactamase VEB-1 (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M4FJ21_PSEAI -------------------------------------------MQSVMKFPIALAVLSEID -KGNLFFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGKNATNDVGVITLPNGQLIFISVFVAE ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingomonas populi TaxID=2484750 RepID=UPI0013EE7AB0 ---ALLNAVQALGAAFHGKVAISVRDVEQGWMV-AWNGERANPQQSVSKLWVAITVFDAID -HRRLSLTTPVTVRRADLTVHQPILPLVGPDGTTVGALLQCALTRSDNTCNDVLLWKVGGP -AAIRRMLTEKGIRGVGFGPGERVLQARYLAAPYDGATANGVTLGLSLLGQRKLLSPASTQ -RLLSIMLASKTGPLRLKSGLRTGWRMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPISARMRLMGNVTRAIIR-- ->[subseq from] Uncharacterized protein n=2 Tax=Pseudomonas TaxID=286 RepID=A0A1E4V439_9PSED ------------------------------------------------------------- ------------------------------------------------------------- -----AVARQLGLAEADLQPSLDQAYQAYYAGGANSAHLTALAEVLEGLADGRALDAAHTD -YLLGLMRQVQTGNQRIRAGLPAATPYAQKTGTQR-ARACDAGLIEPPARAPVLVVACV-R -GDLSMARSERSLRQVGEALT--- ->[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. MA1 TaxID=2607654 RepID=A0A5N1JLZ8_9BACT --eQLRHQIETQLATQPGRYAVAFKDLTTGQTL-LIHEREEFHAASTMKTPVMIEVYKQAA -QKRFSLSDSILIKNESIVDGSPYSYTKIGTKLPLSAVLYDMIILSSNLATNLIIERV-DA -KKVMQTMREMGTKDLQVRRGVEDTK-AFQKGLNNTTTAYDLMVLFEKIATGKAVSPEASQ -DMIRILLDQRF-NSVIPAKLPKTVRVAHKTGSITS-VRHDSGIVFLPDGRKYVLVLLSKE -IKND-TAVVESLATVSGMIYQYf ->[subseq from] Serine hydrolase n=1 Tax=Larkinella knui TaxID=2025310 RepID=A0A3P1CTX2_9BACT -----------------AHVNVAFESLTDATKF-VHLPDEPVPAASVIKLPILIETMERVK -AGQFDLGKIHVLQESEKTGGSGVLQTYPDQSVTNLEVLTLMMTRSDNTATNILIREL-GM -ENINRRMQTLGLTQSRLNRMMMDTLAA-KQGRENRVSAHEMNVLLKKIYRNEVATPELCA -QMIDILKRNSD-QTTFRLFLPKTAVIAHKTGELAY-VRGDAGIFYVA--KPFLLSVFVQG -TT--TPEAEKIIGEIAQICYNQf ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6DKY8_9BACT --kKLEARVDEIAERFDGVMGVAIVDLTDDRAI-LKNTDHVFPTASSIKIAILLELYRQEQ -QGKAKLDDIYTFEAKNLVDGSQIMTGLTPGVLTNRDLAQFTVAVSDNAAANVLIDRV-GM -QNVNATLRNLGLTKTMLRRKMMDIAAARRG-DENVSTPQEMMRLLEAIYQGKALDKELAK -AFMKQLSTKKE--SYIPRQLPPDVSIANKPGDLD-GVRTDSGIVFAKNR-PFAISVMTTY -DRE-ERAAESAIAEIA------- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A1B1S8Z6_9BACT --sQIEERLKTYVAAQDTRIGVAVI-IDGKDTV-SVNGNRDFPMLSVYKFPQALAVADYCM -KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP -QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDSPVHE -AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD -SAYDMARTEKIIADISKIVYQ-- ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=UPI0003016D59 ----LEEKIKSLINEVQGEFGVYFEDTVDGTKI-LLNENIVFSAASTIKIPLVALGLKLYE -EGKFDLNDEIEIKPENRVGGTGVLKTLNRNYPTVSDLMTLAITVSDNVATNQLVDLVGGF -DNINSFSKSLGLNDTKFQRKMLDLKSL-QEGKDNFTTAKDLGTILSLVAKDECVSKESSE -LLLKMMKMQQF-RQKLPNLIPAIVLVANKTGDLWK-VQHDVGIFILPKGERYVISVFSQK -LAED-YEGVETISKISKAAYEY- ->[subseq from] Beta-lactamase n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6MDW4_9BACL ---SLSPSIAKILEEAGGEWGVYLEDLQTGEQL-AFNQDERFYAASVIKVPIMTAVFAEVY -AGKFALESKITLRSEDQVGGAGILQHMTPGSWTVQDLVTLMIIQSDNTATNILIDLV-GR -EAIRAAMQATEMTNSRFFNKLMIVPAQVEG--YNEVTAADLGNHLRYLATGKVISYDSCE -RMIAILKQQQH-RDRIPYHFPPSWEFANKTGSVTK-ITHDMGILYIGSRA-VTICVLNKG -LE--QRPAVQSIAKIGKLVFDLy ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus sp. AK 1817 TaxID=2303505 RepID=A0A5J6PJF2_9BACI ---SLQKIIESYVTNIEADFGIYIKQLQTNEEV-NIQGDKLFQTASVMKLPVLATLYEKAY -KGEINLQQRIQLTEQDYVPGSGVFQEMEYGIPTIQDLATMMIIVSDNLATDKLLKILGGV -TPVKETMDRLGLNNIYIKHSIWELLSYQHNKESNVSSAKDMSLLLELFAKGEFVSTKCSR -EIIDILHRQHY-QQRIGGLLPRNTPVANKTGSLG-AMYNDAGVVYLPDKGQYVICVFSNG -HSLE-YEGDEPIAQISKIAYEYf ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) TaxID=358681 RepID=C0ZAZ5_BREBN ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKIPIMTAVFAEAY -AGKFAFEDKIKLRTDDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMKNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL -KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHAy ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MEL1_9BACT --kKLETRIRDIADKFDGVMGVAILDMTDGRIF-SLNADRVFSTASSIKIAVLVELYRQDQ -KGKARLDETYTFHPKDLVEDSRIMAGLTAGVVTNRDLAQFMVAVSDNAAANILIDRV-GK -DNVNATLRAVGLSKTMLRRKMIDIAAARRG-DENVATPEEMVRLLEPIYKGKVLNNEATA -ALTKQLSTLKQ--SYIPRLLPENVQVANKPGELE-AVQTDSGIVFAANR-PFAICVMSAY -DR-DERAAERAISEVALEAYRYf ->[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A6A0HII2_9BACT -haALDHYLEHLTDSLQAEIGVAFRDLETGQEY-FFNEKSMMHAASTMKVPVMIEVFRQAE -AGKFRLEDSVFVRNQSIVDGSPYSYKVIGQKMSVHDLVYQMITVSSNLATNLLIELV-DA -KKVMATLQQLGIHDMQVLRGVEDGK-AYQLGRNNRTNALDLMLSLQAIAEQRAASPAACQ -AMIAILKDQKF-RDSIPAGLPEGFIAANKTGSIT-AINHDAAIILHPNRKPIVLAILTRK -IT-NHEQARATIAGLTRHLF--- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobium lucknowense F2 TaxID=1450518 RepID=A0A081T6X0_9SPHN ---DLLNAVQGLGTSFKGKVGISVRNMDEGWMV-SFNGGRMLPQQSVSKLWVAIAVMDAVD -HGALSLSDPVTVRRSDLTVHQPIRPLVTKAGTTIGKLLEMALTRSANSCNDVLLWKVGGP -EAIRAMLKRKRINDVGFGPGERKLQARYLANPYDGASANGVTLGLMLLKQGKLLSKSSTR -HLLSLMRASRTGPLRLRSGLRNGWTLAHKTGTGQTTGYNDVGILVSPEGHRYAVAVMIAS -TRAPIPARMRLMGDVTRAVIR-- ->[subseq from] Beta-lactamase n=2 Tax=Francisella salina TaxID=573569 RepID=F8G8P6_FRAST ------------------------------------------------------------- --NKDLLNEKIKILSNQVVGYSPITKEHINQTMTVSQLSRAAI-QSDNTATNLLIEKLGGL -SNLNKFILSLHDHATKVAGLEPIANQVNLTTNQNKTTPKIMARDINKLAFNNILDKKHRL -LFKKWLLGNDSDDNRIAAEIPDEWDVGNKTGTCAYGSTNDVAIIWPDDDRAIIMAIFYTQ -SQENAKPNSKIIREVTKILLDKf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6FNL9_9BACT --kKAESRIDEIATRFDGVMGVAIVDLTDARPAlLRNAEHVFPAASSIKLAILLELYHQDE -KGKARLDDLYTFDPKDLVEDSRIMGGLSTGVVTNRDLTQFMVAVSDNSAANVLIDRV-GK -DNVNAMLRGLGLAKTMLRRKMMDVAAAQ-RGDENVATPHEMVQLLEAIYKGKVLKADSTK -ELIKQLSTLKP--SYIPRELPDGVQVANKPGELE-GVRTDSGIVFSANR-PFAISVMTAY -AR-DDRAAERAISDIAQEAYHYf ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A2N5KJR4_9ACTN -----RRAVEGYEKDHAGIAGAYVVDPEGGLGY-GVRADEPFFGASVMKIPVMIAVYRRMD -EGKLALSDSFKTEKGDWAAGAGWLQWEDPGVHTVEDYLYMMMTQSDNVASNALIRKVGGA -EYVNEVARDLGAENTLIRAKITS-ERAIVTALDNQTTPRDMATMLSEVATGDAASKISCE -DMLDLMYQNVT-DRWLEAGLPNEVYAANKTGWLYK-VYDDAGVVQEGER-PYVVAIFSKH -GPDDVEVGKTLIRDVSWAVWK-- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. FJAT-14745 TaxID=1704289 RepID=A0A0M0X2I9_9BACI -----KQTITQILQIAPYKVHMFVKDCKTEHFFmNEKLEDTFSSASLIKVPILLAVLNYVE -SNNLSLEQEIKITPEEWVDFSVISEQRLEQ-STIYELLVWMIITSDNTATNVLIDFL-GM -DALNQYFREIGLLQTTIQRKMMDIER-LAKGFDNTTSARDMALLFSRIYRRDLLSLAFSE -LTLEILCRQRV-HESLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSSSGD-YLIGVFITE -VTN-NDHARQLIGRLSKVVYDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A346QRV6_KLEPN ------------------------------------------------------------- ------------------------------------------ITMSDNSASNMMLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQ------------- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus boronitolerans TaxID=309788 RepID=UPI0002FF7414 -----EQRITTLIQESPYNVHLFIKNLTTNQLLiGHQLEASFSSASLIKVPILLALLSHIE -KNKLSLDSTLTISPADWVDFSVISEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLSPSYNK -LVIDILSRQRV-HDSLKRYLVDDVRLAHKTGGLAT-VDHDVGIFYTHAVD-YSMGVFITN -VTEN-DHARQLIGHLSKVVYDQ- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_20CM_2_70_9 TaxID=1805058 RepID=A0A1Q8A776_9CHLR ------ARLDALARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL -AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK -GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKAILDPPSCD -AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE -LVRDNVDDDRALAQLSLAVWEE- ->[subseq from] Beta-lactamase n=5 Tax=Staphylococcus aureus TaxID=1280 RepID=D2J6J5_STAAU ------------------------------------------------------------- ------------------HNYTDFIEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Uncharacterized protein n=2 Tax=Fusobacterium nucleatum TaxID=851 RepID=D5RB77_FUSN2 --tEWKKEIKKIILQVEGKVCINFYDLGKNNGF-SINGSEKVLSASMIKLLILAELMKKVS -ENNFSLSDTITITNFMKTEGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINFLGKELGLRETFLERRMMDAEA-SKNGYDNYTSADDLSLLLKLIYQEKLINKETSQ -LMLDILLRQQQ-GERLQRYLPPDIKIAHKCGDLDN-LENDGGIIWLGNK-IYILVVLTSG -MS--NLQCRQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI00047C24F2 ------------------------------------------------------------- ----------------------------------------------------------MGP -QRVQALARTLQVKKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYRDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHVGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4F2M9_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGARAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. nucleatum TaxID=76856 RepID=A0A101K6N2_FUSNC --tEWKKEIKKIILQVEGKVCINFYDLGENNGF-SINGSEKVLSASMIKLLILAELMKKVS -ENNFSLSDTITITNFMKTEGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINFLGKELGLRETFLERRMMDAEA-SKNGYDNYTSADDLSLLLKLIYQEKLINKETSQ -LMLDILLRQQQ-GERLQRYLPPDIKIAHKCGDLDN-LENDGGIIWLGNK-IYILVVLTSG -MS--NLQCRQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000A05C905 ------------------------------------------------------------- ------------------------------------------------------------- -ARVRKVSQLLDVPASRLRMPLEDAYTAYYASGVNSGRLDAYGELLALLVDGRALGRPMTD -YLLQVMERTATGTRRIKAGLPPDARFAHKTGTQRR-RICDAGLITGPRTAAQVLVVACVR -GDLSLERSERALQQVGAALC--- ->[subseq from] hypothetical protein n=1 Tax=Rufibacter ruber TaxID=1783499 RepID=UPI000AD3F6A4 --qKTEAEIRRILEASPAVTGLVAVDLTSGETL-QFNQDMVFTQASAIKIPILLEVYNQAH -QGKFKLTDLREINPANVVGGTGILKDLVDSAFSIRNLAVLMITLSDNTATNALIDLV-GM -PHINATLQKMGYKQTKVQRKMIQSAA-SGRGEENISTPAEAARMLQMLHKGEFVNKAVSQ -EIVSVLKKNSRGNSRLAAGVPANVPLAFKPGGLN-GVSTEWALVLLPER-PYAVAIMENY -KV--VGKAETVLEEVSAVLYQYy ->[subseq from] serine hydrolase n=1 Tax=Clostridium symbiosum TaxID=1512 RepID=UPI00093C4F97 --eELKNRINEFIESQTGNICVALFDLKEQDGF-SIDGDRRVPSASMIKLVIMAELMRRVC -AGELSLEEKIKITQEMRTGGDGVLKEEPGHEFSLREILTLMIIVSDNEATNILIQML-GM -DRINRMAAELGLKEAVLGRKMMDSEA-KKQGRDNFICADDIMLILKKIYEGSCVDRKASA -LMLDILKRQQQ-SGRLQLYLPEDVEVAHKCGDLDF-LENDGGIILLPGH-PYILAVLTNG -VKTNK------------------ ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus sp. A1 TaxID=1571920 RepID=A0A0B1XTP0_9BACI -----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTE -KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE -LVIDILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN -VT-DNDLARQLIGRLSKVVYDY- ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus timonensis TaxID=1268254 RepID=UPI00030304C3 --nKLKKEIEDLVKDSSANISISFYDLDEDEKF-AINGDKKVPSASMIKLLIVLKLLEKVE -RKDLDLEEKIKIQDYEKVDGSGILKELSSNHFSIRELLTLMIIVSDNFATNILIEII-GM -DEVNDLGEKLGLLNTSLQRKMMDLDAK-EKGFDNYTSSHDILKILKMIYEKTFLREDLSD -LALDILLRQQE-RSRLQRFLSEDIKIANKSGDLDN-LENDGGIFFTNKK-NYILVILVNE -AQ-SNVLAKEIIGKISLKIYE-- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium Isolate-007 (NCI) TaxID=2489217 RepID=A0A4Q0IHL1_9BACT --sQIEERLKTYVAAQDTRIGVAVI-IDGKDTI-SVNGNRDFPMLSVYKFPQALAVADYCM -KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP -QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDSPVHE -AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD -SAYDMARTEKIIADISKIVYQ-- ->[subseq from] Beta-lactamase VEB-1 (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A0M4FJX0_PSEAI -------------------------------------------MQSVMKFPIALAVFSEID -KGNLSFEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCEILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGKNATNDVGVITLPNGQLIFISVFVAE ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus phoceensis TaxID=1720298 RepID=UPI000782850A --nKLKKEIEDMVKDSSANISISFYDLDEDENF-AINGDKKVPSASMIKLLIMLKVLEKVE -RKELDLEEKIKIQDYKKVDGSGILKELSWDHFSIRELLTLMIIVSDNFATNILIEIL-GM -DEVNDLGEKLGLLNTSLQRKMMDLDAK-EKGFDNYTSSQDILKILKMIYEKTFLREDLSD -LALDILLRQQE-RSRLQRFLSEDIKIASKSGNLDN-LENDGGIFFTNKK-NYILVVLVNE -AQ-SNVLAKEIIGKISLKIYE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Spirosoma endophyticum TaxID=662367 RepID=A0A1I1YKV1_9BACT ----------------SARVSLSVKSLSDNNVAfKYRADERVPSASVIKLPIMLEAMERVK -AGTLNLDKIYFLKASDKVGGSGVLQNYPDQSVSYRELLRLMMIESDNTATNIFINLL-SR -DAINQRIRTIGLKQSQLNRIMMDTLAA-REGRENYVTAQEMSTLVEKIYRNQVATPKLCL -EMIDVLKQVP-GPLTISRLLPKGTVVAHKTGTLTY-VRGDVGIVYAK--EPFLLSVFVEG -VP--TPEAERIIGELSLICYTYf ->[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. S45 TaxID=1641861 RepID=UPI00131E5B63 ---ALAARLQMLGAGFDGQVGIAVEDVREGWVA-DYNGSILRPQQSVSKLWVALAVFKTAD -FGGLKLSDPVLVRRNDMSVFNQPMQKLLGKDTTIDGLLVGAIAQSDNAANDILVRRLGGS -TAVRRALADERIMGIRTGPEERVLQSAYVADADDGATPLGLVDGLSRLQRGELLSSPSTA -RFLQILASTETGPMRLKAGLGSGWSIAHKTGTGQSTGYNDVGLLTAPDGHTYAVAVMIGA -TRRPIPERQALMADVARAVVAQ- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_2 TaxID=1916214 RepID=A0A292QKT8_9BACT ----LESQLSNLAAMYSIHPSVYVWDYETGNYV-DMNADEIFPTASIIKLPVLVELFRSIE -KNQLTIYDEMPLTEYYRSEGSGSLQFRAANSYTIDKLARMMITESDNSATNMLMARLGSM -TDINSALREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPKFLSNSSRE -KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR -PHN-SPLGKEFIVKASQVIYN-- ->[subseq from] Beta-lactamase n=1 Tax=Geomicrobium sp. JCM 19037 TaxID=1460634 RepID=A0A061NRZ3_9BACL ------QTMQSFIEEKNAVFGVSVTHVESGEHF-SARGDDPFQQASVFKVPILLSLLKKVD -RGEIDLTARVTLTQEDEVYGSGILKELSPGLPTFKDLAVLMIIVSDNLATDKILKII-GL -ETVQKDLTDWGFTRTTMDVTTSDLLAFQTHTETNTTTPNEMNQIYERLLAGELLSPSSTS -IALDILSRQHL-NRRIPRYLPKSVQVLHKTGSLAD-HLNDAGIIRIDDHNTLIISIFSRG -HA-STEAGEDDIAHIANRAV--- ->[subseq from] serine hydrolase n=1 Tax=Planctomyces sp. SH-PL62 TaxID=1636152 RepID=UPI0012E95140 -----------------AFVEVALHDLETGATV-LIRADEPIHPASTMKVPVMLEVYRRAE -AGEFGLDDAIEIKNTSLVDGSPYSYKRIGGRAAIRELVFLMITESSNLATNLLIEKV-SG -ESVTAFMKELGAGDLKVLRGVEDGKA-FAKGLNNVGTARGTMTVLTRLAERTAVSKSASE -AMLEVLRAQKF-NEGVPALLPEGTIVAHKTGSITR-INHDAAIVEPPGRKPFVLVVMTRG -IEAD-RDARRLIAEIARAAYDH- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI0009EC031C ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGLIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A3Q9SCN4_9BACI ---TIEHDILGLVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIRELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNLLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKMIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus sp. 160 TaxID=2052660 RepID=A0A345PKT7_9BACI --eQLSHNIERIIKQSSGKWGIAIEELGTNKSW-GINEEELFYAASIIKVPIMIAVFAAYE -NERLSLSDVLELKIEEMVGGSGVLQYLAPGTLTINDLITLMIIQSDNTATNMLINLI-GK -ENIQQTMKNIGMQKSKFYNKLMTVPANLQG--YNEITAQDLTMILKKLAAGKIVSMHACG -RMIEIMKKQQL-TDCLPAKLPQTWQLANKTGFVS-GVRHDIGIFYVGDRA-MATTVLSQD -LD--DHHSKDAIAEIGLEIYRY- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI0006B2F008 ---PLERALARVEADSGVRIGVYVRDLDTGASA-SLHGAEPWYLASSVKVPVAIAVLRGVE -RGDFTLETSLTLRAADYVDGAGPTNSRPVGTLTVRYLLEQMIIYSDNTATDMLIGLV-GI -GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQALVEGRALDARHTA -YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRLLVVACTR -GEPSTARSDRALRQVGIALC--- ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingomonas TaxID=196159 RepID=UPI00055FE90B ------NAVQALGAGFRGQVAISVRDVDRGWMV-AWNGDRPHPQQSVSKLWVAIAVFDAID -HARMSLATPVKVIREDLTVHQPIRPLVGPNGTTVGALLECALTRSDNTCNDVLLWKVGGP -AAIRRMLKEKGIDGVGFGPGERELQARYLAAPYDGATANGITLGLSLLAQDELLSYGSTD -RLFRIMLASKTGPLRLKSGLQPGWKMAHKTGTGQATGYNDVGLLTAPNGHRYAVAVMIAS -TRQPIPVRMRLMGNVTRAIIR-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Planctomyces sp. SH-PL62 TaxID=1636152 RepID=A0A142YN72_9PLAN -----------------AFVEVALHDLETGATV-LIRADEPIHPASTMKVPVMLEVYRRAE -AGEFGLDDAIEIKNTSLVDGSPYSYKRIGGRAAIRELVFLMITESSNLATNLLIEKV-SG -ESVTAFMKELGAGDLKVLRGVEDGKA-FAKGLNNVGTARGTMTVLTRLAERTAVSKSASE -AMLEVLRAQKF-NEGVPALLPEGTIVAHKTGSITR-INHDAAIVEPPGRKPFVLVVMTRG -IEAD-RDARRLIAEIARAAYDH- ->[subseq from] Serine hydrolase n=2 Tax=Halomicronema hongdechloris TaxID=1209493 RepID=A0A1Z3HP37_9CYAN ------------------TQATFMVDLDTGDYV-DVNGSTPVPAASTIKVPILVALLQAID -AGQVTLDQGLTLRQQDLAGGSGLREQPLDTQYPVLEVATQMIVSSDNTATNMIIELLGGA -TALNQQFRQWGLSATVIRSPLPDLGGT------NTTSAQDLVTLMARVNQGELLSLRSRD -RLLAIMQRTDN-RSLIPSAAGNGAIVANKTGDIKS-LLGDVALVDTRSGKRYALAILVQR -PDND-GRAGELIRRITERVQ--- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D210B4F ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A4S2FWR7_9BACT --sQIEERLKTYVAAQDTRIGVAVI-IDGKDTI-SVNGNHDFPMLSVYKFPQALAVADYCM -KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGP -QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDNPVHE -AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD -SAYDMARTEKIIADISKIVYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. N3536 TaxID=2666127 RepID=A0A6B8K3D4_9BACI ---SLQKIIESYVTNIEADFGIYIKHLQTNEEV-NIQGDKLFQTASVMKLPVLATLYEKAY -KGEINLQHRIQLTEQDYVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLATDKLLKILGGV -NPVKETMDRLGLNNIYIKHSIWELLSYQHNKESNVSSAKDMSLLLELFAKGEFVSTKCSR -EIIDILHRQHY-QQRIGGLLPRNTPVANKTGSLG-AMYNDAGVVYLPDKGQYVICVFSNG -HSLE-YEGDEPIAQISKIAYEYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3WLF1_BRECH ---NLSTQISQLVENAGGEWGIYLEDLHTGEKL-TFQEHQRFYAASVIKVPIMTAVFAEAY -AGNIALEQTIKLRREDLVGGAGVLQHMTPGTLTVQDLVTLMIIQSDNTATNIMIDLV-GT -ESIRNAMKKTEMVNSQFYNKLMVVPAELEG--YNEITAADMGAHFRYLATGKVLSYDSCL -KMMAILKQQQH-RDRIPKHFPPKWEFANKTGSVTK-ITHDTGILFMGSHA---VTICLLN -KGLEQKPAADVMAEIGRLVYDLy ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. BA3 TaxID=2057910 RepID=A0A2N0Y689_9BACI ---TIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE -RILRALDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Larkinella sp. MA1 TaxID=2607654 RepID=A0A5N1J9H0_9BACT ----------------QTQVNVAFESLTDSTRF-FHLSDELVPSASVIKIPILIETMEQVK -ARKFDLDKVHVLLASEKTGGSGVLQTYPDDSITNLEVLTLMMTRSDNTATNILIREL-GM -DHINRRMQTLGLTKSRLNRVMMDTLAA-KQGRENRVTAREMNLLLKKIYRNEVATPALCA -QMIDILKRNAD-QTTFRLFLPPSAVIAHKTGELTY-VRGDAGIFYVT--KPFLLSVFVQG -TT--TPEAEKIIGEIAAICYNQy ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus sp. DNF00840 TaxID=1477000 RepID=A0A134APC4_9FIRM ----LQNKIENIVEESSANISVSFYDLDFGEGF-SIDGDKQVPSASMIKLLILLKAFYESD -KGKLNLEDTISLDDYERVEGSGILKELYRDHFSIRELLTLMIIVSDNTATNILIDLL-GR -DEINKIGHELGLEKTILQRKMMDSLAK-EKGLDNFTSSDEILKILKMIYEKDFINEDYSQ -LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ -AE-SNVLAKEIIGEISLKIYK-- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax oryzae TaxID=862720 RepID=UPI00035D588F ------------------------------------------------------------- ----------------------------------------------------------MGP -QRVQALARTLQVKKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYRDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus muralis TaxID=264697 RepID=A0A1B3XL97_9BACI --qTIENDILALVEAFDGKIAYK-LETDLGDTI-GYHEEDLFQSASLIKIPMIIEGYRQSE -RKKIYLNQPVTIPSKAVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTATNMMMSLL-GF -EEINRCMKDLGLKNTILEREMQDFKA-LKEGRDNTITAEDAITCLKSIHTGDFLTKESQE -RILRVFDNQQL-RDKLPSLMGKEVKVANKTGGIR-GVSHDCAIIRLKSRT-VYAAVLTEN -IK-SEEESRQVISKIGKLIYD-- ->[subseq from] hypothetical protein n=1 Tax=Nodosilinea nodulosa TaxID=416001 RepID=UPI000305B09C ------GELENLATLTGLTPLAFAVDLDSGQYV-DLGGGEPIAAASTIKMPILVAFLQQVD -AGTMDLNQAMVLREEDVAGGSGTMHSAVGTQYTALEVATHMIVSSDNTAANMMIAALGGM -EALNQTFASWGLEQTLLRNPLPDLDGT------NTTSAKDLALLMALIDQGGLLTPRSRD -RMFSIMQRTEN-ASLIPSGITDGSITAHKTGDIGT-MLGDVALIDVPNGKRYALALLVQR -PDND-GRASELIRRMTTTVH--- ->[subseq from] Beta-lactamase n=1 Tax=Chlorogloeopsis fritschii PCC 6912 TaxID=211165 RepID=A0A3S0Y4H3_CHLFR ---KLYDRIEKISRAAQGRVGVAATVLETGESV-ALNAEQRFPMQSVYKFPIGMAVLAQVD -KGKLKLEQRVRVEKSDFVSHSPIRDNNLQGVLSIAELLKYMVSESDGTACDVLLRLIGSP -KVVTEYLRELGVNDIVVANTDKEIGQDKSVQYRNWTTPEGAIALLRALHEGRGLSKSSQA -LLLRLMIETPTGLQRIKGY----------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium sp. HMSC065F01 TaxID=1739435 RepID=UPI0008A4892C --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM -ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Elusimicrobia bacterium RIFCSPHIGHO2_02_FULL_61_10 TaxID=1797944 RepID=A0A1F9W9P1_9BACT --tELHQKINYQIRHFPGVAGIYIRDLKTGWTI-EYNADKLFPSASLVKLPIMAVLYQAQV -AGRLSLDESLPVLRKLKARGSGHLRRRLGSRVSVRELVYKMITESDNTATNMLADRL-DM -DYINRHFLALGLSRTNFARMIMDLRRR-DQGIENYTTAHDMGNLLEMIYSKKLT---GSE -EMLEILKGQKI-NDRLALGVPSEWQIGHKTGLMNN-ACHDVGIVFSPTSD-YVICVLTTN -IR-SFRRPKNFISEISYLAASYf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PBV1_9CHLR ---------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL -AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK -GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD -AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE -LVRDNVDDDRALAQLSLAVWEE- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536CUF2_9CHLR ---------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL -AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK -GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD -AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE -LVRDNVDDDRALAQLSLAVWEE- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PE01_9CHLR ---------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL -AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK -GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD -AILALMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE -LVRDNVDDDRALAQLSLAVWEE- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:715 TaxID=1262834 RepID=R5DJN9_9CLOT ----LESQLSNLAAMYSIHPSIYVWDYETGNYV-DMNADEIFPTASIIKLPVLVELFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFRAANSYTIDKLARMMITESDNSATNMLMARLGSM -TDINSALREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPKFLSNSSRE -KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR -PHN-SPLGKEFIVKASQVIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Ureibacillus thermophilus TaxID=367743 RepID=A0A4P6USA3_9BACL ------EQIRTLLKQVDCKTHLFVKDLKTNEYLiAEKMDEVFSSASIIKVPILCAVLHYVQ -EHQLSLNHSVDISPENKVDFSVITEQDLTT-STIYELLYWMTVVSDNSATNVLIDLL-GF -DYLNTYFHNIGLKNTKLQRKMMDFDR-LNQGYDNVTTARDMADLFTMISQQTLLPEKLNR -LAIDILCKQTD-YERLKRYIK-DARIAHKTGSLDT-VCHDVGIVYHRNGN-YIIGVFLTE -VR-DFEMGKRWIGRISKMVYDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas sp. AG1028 TaxID=2572911 RepID=A0A561DWT1_9PSED ----LLERLQAITAKQNGELGVYVKDLHSNLAV-TLRAEERWYMASGIKVPVAIAVLRGVE -RGDWQLDTRLSLEADDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLA-GL -DAVNGLVRELVPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLATGQALGNEQTA -YLLSVMSRVKTGSKRLIAGLPKDARLAHKTGTQR-ARICDSGLIETPQRAEPVLIVACVQ -GELSLSKAERTLRQVGEALTD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A317IGA4_9BACT ---DLEKRLTDMSLLKGMHTGVFLVEPKTGKYA-DVNGHDQFAAASIIKLPVLVSFLIHLD -RKEIKMDEKLTLRQDLMAAGSGHLQWKVGSKVTVREAAELMITVSDNTATNLLIEALGGK -AGLNEEFARWGLTQTKINNMLGDFEGT------NKTSPYDLVYLLGRIDRGELVSPASRR -WMLAVMERTRI-RTLLPQGIGPGAKIAHKTGDIGC-MVGDAGIITSPLGVRYLIAVQVER -PRND-RRANVLVRNISKEIYN-- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax citrulli TaxID=80869 RepID=UPI0006625689 ------------------------------------------------------------- -----------------------------------------------------------GS -QRVQALARTLQVQKDDLKKTMEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE -DMDEMRQAGRLFEQLGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus lasiicapitis TaxID=1636719 RepID=A0A544TBQ6_9BACI ---TLKQQIESYIEGIDANFGIYIKHLGTQEEV-NIQGNLLFQMASVFKVPILATLYEKVF -NGEINLQERVPLNEEDYVPGSGVFQEMQYGIPTIKDLATMMIIVSDNLATDKVLSIVGGA -NNVQERMHQMGFKDIYIHHTCWELLSFQDSTENNVSSAKDMSLLLEKIALDEFVSPDCSR -EIREVLFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDTGIVYLPDNGEFVITVYSTG -SSLE-YKGDEPIARISEIAYQYf ->[subseq from] Beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4U9LAA2_ECOLX ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWG--------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium CG1_02_37_114 TaxID=1805131 RepID=A0A1J4YVZ0_9BACT --eKLAKDINVMAKNLPGRVSFVIKDLRTGVCI-KQNADELFPSASLVKVPLMACVYKAAE -DGLLSLDEKLILKRSHRVEGKKLRYCRIGTKLEITRLIELMIDESNNIATNMLTERL-GL -DYINDTFKQFGLKKTNFDRYIMDLKAR-NRGIDNWTTAEEITELLEKIYSRKLVNSKASE -QMLEILMKQEI-RDRIPKWLPKDIQIANKTGYLRQ-TCHDAGIVFSVNGD-FIVCVLTHG -VKKT-KLAKNFIREVGYRTYMQy ->[subseq from] Beta-lactamase class A n=2 Tax=Bacillus TaxID=1386 RepID=A0A561DAM2_9BACI --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKMIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus massiliglaciei TaxID=1816693 RepID=UPI000AA7E597 --qAIEKEVLQLAEEFNGKFACQIVW--DEEII-DYHSDERFQSASLIKIPMIVEGFRQAE -AKEIYLNQPVTIRREQITGGSGVLHALSDKVLTLEDLLTLMITVSDNTSTNILIDLL-GF -DKINQCCRDLGLKNTVLERKMFDFKAK-KEGKDNFITAADTITSLKAIHTGSVLSKESHE -KILRVFENQQF-REKLPARMGKGVKVAGKTGGIQ-GVSHDAAILRSDTQ-TVYAAVLTEE -IT-SDEDSRQVMGKIGKLLYDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas straminea TaxID=47882 RepID=A0A1I1RQV1_PSEOC ----LLERLQAITAKQKGELGVYVKDLHSNLAV-TLRAEERWYMASGIKVPVAIAVLRGVE -RGDWQLDTRLSLEADDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLA-GL -DAVNGLVRELVPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLATGQALGNEQTA -YLLSVMSRVKTGSKRLIAGLPKDARLAHKTGTQR-ARICDSGLIETPQRAEPVLIVACVQ -GELSLSKAERTLRQVGEALTD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8AP61_9BACT ---KFEQRLQQISSRVDGVVGYSVLDLTSGDRI-AHLERETFPTASTIKLAIVYELFRQAA -EGRIRLDDTIALDRAKAVGGTGVLFQLGTPMLSVRDYATLMVIVSDNTATNVLIDRL-GM -QNISARMQSLGLGATKLRRHMMDTAAARRG-DENVSTPDEIVRLLQAIEKDE---PDASA -----LLKKPK--ESRLRRALPPGVEAADKPGELD-GVRVDAGIVFAKNR-PYALCVMATF -LT-SEVEGERAIEEMSRAAYDYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Oxalobacteraceae bacterium TaxID=1871070 RepID=A0A4Q3JTY0_9BURK ------------------------------------------------------------- ---------------------------------SAAKLLELMIVRSDNVAADQLLASLGGP -GALQQWLRLRGITGIRVDRTIAQLLRDHLADSRDVATPNAMVSLLSKLNNGDVLTDKSRA -LLFALMSRCSTGTRRIRALLPTGTRVEDKTGTLD-GVTNDIGVVTMPDGHRVALAIFARG -GR----DRQLGIAQLARAIYDRf ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3C1EM50_9BACT -----TQALGALAARHPGRVSIMLKDLKSGRCW-TYHPDDLFPAASLIKVPVMISAFYKIS -EGELSLNEMLVLRRRTRVGGSGSLKWRPDGTLSVSELLIHMINESDNTATAMVLDRL-GI -GWVQQQFPRMGLLYTGIYPEGMSIKGG-RVAHENYTTAREMSMLLEKIYRGEIVDKDSSA -LMLEILKRRKAVPSRLAKGLPRGWEIAHKTGLLRM-ACHDSAIFFTPNGD-YVMTVLTGQ -NR-SYHAAKDFISRLGRITFRYy ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10180 TaxID=2666137 RepID=UPI001391E23E ---ALEEGILSLMQATEGDFGVAFRMLDSGKEL-LINEKEVFHAASTMKTPVMIELFKQAG -AGKFDLQDSILIVNESIVDGSPFSYERIGEKTTIYELMYQMIIKSSNLATNILIDLV-GA -EKVTQSMRELGAEDIEVLRGVEDLKA-FEAGLSNTTTALDMMRIMEAIALGKV---EGSE -EMMKILSDQYF-KDLIPKLLPADVKIAHKTGSIT-GVQHDAAILELPNGNRYVLVILSKN -LA-DVAAGKETIAEISRLIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=A0A323TUG7_FUSNU --tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS -EDKFSLSDTIMMTNFMKTGGDGVLKELNAGHFTLKELATLMIIISDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax citrulli TaxID=80869 RepID=UPI000324B3E0 ------------------------------------------------------------- -----------------------------------------------------------GS -QRVQALARTLQVQKDDLKKTMEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE -DMDEMRQAGRLFEQLGRAITR-- ->[subseq from] Beta-lactamase n=2 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RJT0_9BACT ----VERRVAELRGTADAFVAVAWRDLGTGERL-DLHGDSVFHAASTMKVPVMIELMRRSD -RGALALDQEILLVNRSIVDGSPYAYALVGRRVAVRELIRRMIVRSSNLATNALIALA-DP -AQVTATAASLGAVRTRVRRGVEDQK-AFDKGLNNVTTASDLAALLEAIERGRAASAGACA -EMRRVLLGQELDAGSIPAGVPPGTRVAHKSGQIT-GVLHDAAIVYPRGRPPYVLVVLTRG -IP-DEKLAAAAIADVSRLVYAY- ->[subseq from] Serine hydrolase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A4Y8U7S9_9BACI --qTIEHDILALVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -MQ-SEEESRQVISKIGKMIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Erythrobacter lutimaris TaxID=1538146 RepID=A0A395LHT4_9SPHN ---AFERQIANLADGSDGRIGVYAIDLVTGQEV-GILADQRFPMASTSKVAIAATFLAGVD -QGRWSLTSEFELPG-------------RGKYISAREHLDLMISRSCNDCTDALLYAVGGP -QAVNAWMRNAGISEFELTRDIATLVRASQIAFEDSASPRAMGQLLAGIYQGKWHSSYSRQ -VLMNAMSATVTGKRRMTSALPMSANLAHKTGTLSR-TASDIGIFYTPDGRPIAAAIYVTG -QSPSMAVE--------------- ->[subseq from] hydrolase n=1 Tax=Leptolyngbya sp. PCC 6406 TaxID=1173264 RepID=UPI0002AC8BDE ------------------TQSTFLLDLDSGRYA-DINGGTAIAAASTIKVPILVAFLAAVD -SGRLTLDQAVTLQESSVVGGSGEMQTALGTRYTAYTVATEMMIASDNTATQLMIELLGGA -SALNQQFQSWGLRSTVLRNPLPDLEGT------NTTSPRDLVRILTLVEQGDLLQPRSRD -RLLSIMQRTYS-RDLIPAGIAEGALVFNKTGDIGT-LLGDVALVEAPNGKRYILSTLIQR -PHND-GRAAELIRRIAETVH--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536IJ97_9CHLR ---------DSLARDI-GIVGVSATHLTTRRHI-GVREDELFPTASVIKLPLLVTMYEESL -AGRLDLTERVRYDAGTRVAGSGVLQYLDAGLPTVRDLAVLMMSVSDNTATDLLLERV-GK -GRVEAAMGRYGLRSIRIPFGIREMLMVIPA-QADRSSPRDMCRLLELLARKEILDPPSCD -AILGLMERIQS-GTRLPGLLPKGTVVAHKTGSYRR-VRNDVGVVYAPNGA-YAVAIFARE -LVRDNVDDDRALAQLSLAVWEE- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542SFR2_9BACL ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRAEDLVGGAGVLQQMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLGTGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSLLNKG -LE--QKDAANVMAQIGTLVYRVy ->[subseq from] serine hydrolase n=1 Tax=Spirosoma lacussanchae TaxID=1884249 RepID=UPI001108B7FB ----------------SARVSVAVESLADSSVSyARRADERVPSASVIKLPILLEAMERVK -AGTLDLDEIHILTDAEKVGGDGVLKTYSHRSIAYRDLLRLMMVYSDNTATNIFINEL-GM -DAINARIRAVGLPKSQLNRVMMDTLAA-RQGRDNYVTCFEMNRLLKKIYRRQVATPELCE -QMLTLLKQNED-TLTIPRLLPPGTVVAHKTGTLSY-IRADVGIVYA--RQPFLLSIFVEG -LP--TADAERTIAETARICFTYf ->[subseq from] Beta-lactamase n=2 Tax=Fusobacterium TaxID=848 RepID=R5XJ41_9FUSO --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSDHFTLKELATLMIIVSDNQATNILIDFL-GM -KNINLLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQKKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG -MP--NFQCKQTIGKISKFVYDK- ->[subseq from] CubicO group peptidase, beta-lactamase class C family n=1 Tax=Parapedobacter composti TaxID=623281 RepID=A0A1I1KP95_9SPHI ---DLRKRIGQIMKRHKGRFAYALLDMQNGEQL-LYNAGETFHAASTMKTPVMIEVFRQAA -AGKFRMTDSITVYNESIVDRSRYSYARIGTKLTRHDLVYRMITESSNLATNILIDQV-GA -KSVMKTMKTMGANDIQVLRGVEDTK-AFEKGLNNTVTAYDLMLLFKHLAAGTAVDRASSE -AMVDILKAQRF-RSMIPARLPDDVVVAHKTGSITE-ILHDSGIVYLPDGRAYVLVLLSGG -LPDD--DARNALASISRLVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobium baderi LL03 TaxID=1114964 RepID=T0GLK2_9SPHN -------------------MGISVRDIDEGWTV-SFNGDASLPQQSVSKLWVAIAVMDAVD -RGKLKLSDPVTVRRSDLTVHQPIRPLVTKSGTTIGKLLELAMTRSANSCNDVLLWKVGGP -SAVRTMLARKGVSGVGFGPGERVLQARYLAAPYDGASPNGITLGLAMLKRGELLTPASTR -HLLSLMRASRTGPLRLRSGLRSGWTLAHKTGTGQSTGYNDVGILNSPDGHRYAVSVMIAS -TRQPIPVRMRLMGDVTRAIIR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax sp. CF316 TaxID=1144317 RepID=J0TZ42_9BURK ----LQAELVQVAAQNTAGIGVYVRDLETGIAV-SHRGMERWYLASTVKVPVALAVLQAVE -RGEFTLDTKLRVRASDYVDGAGQTNKAVGTALSVRYLLEQMVIYSDNTASDMLIGLV-GI -RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVHGKIVNPEHTR -YLLAVMERVQTGVYRVQAGLPKAARFAHKTGTQR-ARTCDSGLVTVPGRDRRVIVVACTR -GELSSARSDRALRDVGAALCQ-- ->[subseq from] DUF3471 domain-containing protein (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4V1UFY2_9BACT ---DLNKKIASIFAAHEGEFAVAFKDLSTGKEL-LLNARTNFHAASTMKTPVLIETFKQAA -AGKFSIDEPILIKNESIVDGSLYHYTKVGTKLPLRDVLNRMITRSSNLATNIVIDLV-GA -TNANASMRSLGAKDIQVLRGVEDDK-AFQKGLNNTTTAYDLMLIMEAIANGKAFDQKASD -EMLKILFDQKF-NDKIKKKLPPEVKVASKSGSIT-AVSHDSGIVYLPDGRKYVLVLLSKG -VQ-SYDEVNNTLANVSRLIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C0ZGX7_9BACT ---DLKRSIDAEFRKVEGVFGLAFFNLRTGEML-LINEREMFHAASTMKTPVMIEIFKWVK -EGRLSLGDSIEVKNESIVDGSSYQYRRIGGKATIRELMYQMITVSSNLATNILIDLV-DA -KNVSATMRSMGAVNIRVLRGVEDGQA-FRKGLNNTTDAYDQMLILRAIAEGRAVDSASSK -AMIDILFEQKF-NDLIPALLPKNVRVAHKTGSIT-GVEHDCGVVFLADGRRYVLVILSKE -LK-DVKGGKDVIARVSKMIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0AVG0_9BURK ---RLQASLEMLDERVHADVGVYVHDLTTGIAV-AHRAHESWYLASMVKVPVALAVMQAVD -RGEISLDTRMTLRAADYVDGAGNTNSMAPGTLSVRHLIEQMIIYSDNTASDMLIELV-GL -DAVNALVQTVIPGGMRPITTLADVRRAYYATRVNSGPLDAYGALLAQLAQGRVLTPASTD -YLLKTMRRVKTGDRRLKAGFPPATLFAHKTGTQR-ARFCDAGIVDIPSARQAVIVACVSG --DASLTRSEQALKEVGTVI---- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0012472D00 -----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTE -KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE -LVIEILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN -VT-DNDLARQLIGRLSKVVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9KZN1_9BACT -haKLEAEINRVADRLNGVLGYAIKDLSTGESF-YRNADLVFPTASSIKLAVLLELMRQDQ -EGTLSLNEKHTVRHSELPPTDPILHMLGDGTMTLRDVATFMVVLSDNGATNILIDRA-GM -DNINAEIARLGLTQTHLRRRMIDIEAARRG-DENVSTPRELMALLEKVRGGGALDAAHTK -EYSDLLGLPK--DSLFNKALPATVRIEDKPGALD-AVRCDAGIIEVPGH-PFAMSVMTTY -LG-SNDQGERAIKQIARLAYEHf ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3A0E280_9BACT ---KVQLELESIAADVQGVMGIAVEDLAGQHRF-AVNEGLQFAQASAIKIPILMEVLKQAH -EGKLKLEEMHWIEKQYQVAGSGVLGEHRTTQMSLEDLCVLMIVLSDNTATNMLIDRV-GM -DEVNRTMESLGCRHTKLRRRMMDVAAAQ-RGDENVSTPADAARIMRTLHEGQFVSREVSD -HVLAILRKDKPGD--VKAALPAGTSVAFKPGAIP-GVAAEWAIVELERR-PYIVVAMGGF -GV--KEEFKDAFREVSKTAYEFf ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=A0A1U7M079_9FIRM ----LEEKIKSLINEVQGEFGVYFEDTVDGTKI-LLNENIVFSAASTIKIPLVALGLKLSE -EGKFGLNDEIEIKPENRVGGTGVLKTLNRNYPTVSDLMTLAITVSDNVATNQLVDLVGGF -DNINEFSKSLGLNDTKFQRKMLDLKSL-QEGKDNFTTAKDLGTILSLVAKDECVSKESSE -LLLKMMKMQQF-RQKLPNLIPAIVLVANKTGDLWK-VQHDVGIFILPKGERYVISVFSQK -LAED-YEGIETISKISKAAYEY- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0004041F3B ---EWKEKIKKIISQSEGQVCVNFYDLDRKEGF-SIDGDKKVLSASMIKLLIIAELMRQVS -ENKFSLSDKITVIEVMKTGGDGILKELESNHFTIKELATLMIIVSDNEATNVLIDFL-GM -NNINQMAKNLGLKETYLGRKMMDTEA-RKNGYDNYTCANDISLLLKLIYQEKLINKEASQ -LILDILLKQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENNGGIIYLSNKT-YILVVLTSG -IS--NLKGKQTIGKISKFIYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-21352 TaxID=1581030 RepID=A0A5E8L2S9_9BACI ---TIEHDILGLVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIRELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKMIYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A539EG41_9BACT ----MTAELQRTASSSRWRTAVYVKDLQRGYEW-AYHAEDLFPAASLIKLPIMVGVFEKIQ -RGQLSLYSKLKLRRTTRMGGSGSLKWQRDGTYTVRYLLEKLIKESDNTAMLLLLDEV-GI -GFLQQYFPQMGLVYTEINSDGLRLDSG-GVRTENYTTAREMGAVLERIYRGELVNGFASE -LMLDILKRKRA-RTRLAKHLPPGWQIAHKTGLLRR-SCHDAGIVFSPNGD-YVMVVLTGR -VD-SYPAAKELIARLGKTTYRTy ->[subseq from] Beta-lactamase class A n=1 Tax=Nostoc sp. (strain ATCC 29411 / PCC 7524) TaxID=28072 RepID=K9QV33_NOSS7 ---QLDSQIKSLMARYSLSPGMFFLDMETGEYL-DINGEKIFPAASTIKFPILVALFQEIE -AGRVRTNETLVMRRDLMTGGSGNMQQKPGTKFNLLETANRMMIISDNTATNMIIDRLGGK -NRLNERFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLAALISNEKLLGSSGYT -QVMNIMSRCKN-RSLLPVGLGKGAAIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGILVAR -PFRD-ARARSFINQVSRLVYG-- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. animalis ATCC 51191 TaxID=997347 RepID=F9EL26_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM -ENINQLGREVDLKETFLGRKMMDIETR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKT-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A098FBC7_9BACI --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Acidovorax TaxID=2684926 RepID=UPI000D3346ED ----LQAELVQVAAQNTAGIGVYVRDLETGIAV-SHRGMERWYLASTVKVPVALAVLQAVE -RGEFTLDTKLRVRASDYVDGAGQTNKAVGTALSVRYLLEQMVIYSDNTASDMLIGLV-GI -RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVHGKIVNPEHTR -YLLAVMERVQTGVYRVQAGLPKAARFAHKTGTQR-ARTCDSGLVTVPGRDRRVIVVACTR -GELSSARSDRALRDVGAALCQ-- ->[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A3B9LUP8_9BACT ---KFSHRVEDIASHVDGVVGYAALDLTSGDRF-GHLEKDTFPTASTIKLAIVYELFKQVK -EGKVRLDETMVLDRSKAVGGSGVLSQLGTPTLSIRDYATLMVMLSDNTATNVLIDRL-GM -DAITRRMQSLGLGGTKLRRHMMDTAAARRG-DENVSSPEEIVRLLQIINQNQ-------P -DAIALLKKSKE--SHLRKGLSAGVETADKPGELE-GVRVDAGVVFAKNR-PYILCVMTTF -LK-NEADGERAIEDISRAAYEYf ->[subseq from] Uncharacterized protein n=1 Tax=Tumebacillus avium TaxID=1903704 RepID=A0A1Y0IVM2_9BACL ------PALQNLIEAARGTYGVSIYHLESQSEF-SYQADEWFYAASIIKVPIMAAVFDQAF -KGKLSFEEKIALRAEDMVTGSGLLQNLSPGLLSIYDYTMLMIIDSDNTATNILIDRI-GT -QAIQDAMAEWGLTGSGFYNKISVIPAKIEN--FNTITPRDMTRLLKLIADGKVVSWRACA -EMVKIMKQQKY-NEGLPSLLPQQWECAHKTGWVN-GTDHDMGLLYFPHHT-FAVSVFGKN -IT-DRKDAHHLMGQIGRLLYDH- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium TaxID=1930536 RepID=A0A520Y9Q0_9SPHN ---ALGTDILERVRSFNGTSGIAVHSIDGGWET-GWQTARLFPQQSVSKLWVSLAVMDQYD -RNELDLRKRVTLDRDDLTLWSSATRASILRGRTLDQLMYDALVSSDNHANDRLLREVGGP -EAIREMIERKGLGDIRFGEGERLMQARYLDDPYDGASPLAIVRALAKLERGELLSPASTA -KLLTTMGMAKTGRLRIKSSLKPGWTWIHKTGTGQVGGLNDIGILSAPDGSSYAIAVMTIP -NST-DGSAQELMRDIGSMVIAH- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus fusiformis ZC1 TaxID=714961 RepID=D7WTR3_9BACI -----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLEASFSSASLIKVPILLALLSYIE -KNKLSLDSTLTISPTDWVDFSVISEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM -AYLNDYFQHIGLQDTLLQRKMMDVDR-LAKGIDNRTSARDMAHLYTCIYQQELLSPPYNK -LVIDILSRQRV-HDSLKRYLIEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Putative beta-lactamase n=1 Tax=Bosea sp. LC85 TaxID=1502851 RepID=A0A085F0Q8_9BRAD -------------------------------------------MQSVFKLPLAVAVLQSIE -AGKLRLDQEIRVKRNELALWSPMKKGFTGEEYTVTDLLTRSTGASDNSTADVLMKRIGGP -KVVTTMLSEGGIAGISVDRYEREFQPYIKGEVRDSTTPEASIAFLEGLARGNWLREPADR -LLTEILVKSPTDAQRVRAGLPTGATFAHKTGTGDNSATNDIGIVALPDGRRFAIAVYLAG -AKVDAKGREAAHAAVAKLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nakamurella lactea TaxID=459515 RepID=UPI0006843654 ---EAEQRVRDLVRPAPGRVAVVARAVPGGQGF-SVAGDESFTSASLIKVPVLVSALQQVE -AGALSLTQRVRVDTSPRVGGSGILAGLSDVTVSIRDLLELMITISDNLATNLLIETL-SV -PTIAASIEAAGLTNTALQRRLMDLQAR-SRGLDNHTCATDMALLLEQIAVGEGLSADSYR -LAREVLARQQV-NDRLPRQLPHGWVLAHKTGELD-GVRHDAGFVTVDSSPVLVIAVLTEG -FGAYGAAAADLVADVGRIVYS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A2A4BLA4_9BACI --qTIEHDILALVETFNGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8A5Y5_9BACT ---KFEQRLQQISSRVDGVVGYSVLDLTSGDRI-AHLERETFPTASTIKLAIVYELFRQAA -EGRIRLDDTIALDRAKAVGGTGVLFQLGTPTLSVRDYATLMVIVSDNTATNVLIDRL-GM -QNISARMQSLGLGATKLRRHMMDTAAARRG-DENVSTPDEIVRLLQAIEKDE---PDASA -----LLKKPK--ESRLRRALPPGVEAADKPGELD-GVRVDAGIVFAKNR-PYALCVMAAF -LT-SEVEGERAIEEMSRAAYDYf ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A4Q0IAL4_9BACT ---DMETELKTYVHDKDARIGVAVI-INGMDTV-SVNGKRDFPMLSVYKFPQAIAVADYCS -RHNILLTDSIRISASEMKPWSPMREKYGRKDLPLSEILAYSVQQSDNNACDVLFRLIGGP -QVADSLMKKLGYDEIRILNTEDEMHADPYLCYANRATPLQMAALFDRLYRQEMRHSPVLE -AVGAMMMQCVTGNNRLPLPLPTNAMIGHKTGTGDVNGVNDAGYVFLPNKQGYAIAVFIAD -SGYGMTETEKMIADISEIAFK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonas glacialis TaxID=658225 RepID=A0A502FFC7_9SPHN ---DLLNAVQALGSGFPGQVGIAVRDVTEGWIV-GYNADRLLPQQSVSKLWVAIAVMDAVD -RSTLKLSDIVTVRRSDLTVHQPIRPLVGIDGTTIAALLQGAMTRSDNTCNDVLLWKIGGP -PAIRRMLMQKGIAGVGFGPGERLLQARYLAAPYDGASANGVTLGLARLQRGEVLSNSSTL -HLLTLMAASKTGPLRLKSGLRSGWTFAHKTGTGQSTGYNDVGLLKSPDGHSYAVAVMIAS -TRRPIPARMQFMGNVTRALIR-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium GWA2_66_18 TaxID=1797926 RepID=A0A1F9R057_9BACT ---KMTAALDKTAVHYPGRVSICMRDLRTGKTW-MYHPDDLFPAASLIKVPILIAAFYKMK -DGQLSLEEKLPITRRNRVGGSGSLKWRPDGTLAVRELLIHMINESDNTATKMVLERL-GL -GYVQQQFPRMGLLYTGIYEEGMSIKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKPSSD -LMMEILKKPKAVASRLAKGMPTGWEIAHKTGLLRQ-ACHDSAIFLTPNGD-YSLTVLTGQ -NQ-SYSQAKTFITKLAHVTFANy ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetales bacterium 71-10 TaxID=1895807 RepID=A0A1U7GIU8_9BACT ------------------------YDFATGATH-LIRADEPIHPASTMKVPVMLEAYRLAE -AGGLRLDDEVEVKNTSLVDGSPYSYKRVGGKATVRELVFLMITESSNLATNILVEKV-GA -KAVTDFMAKLGAPDLKVLRGVEDDK-AVKAGMNNVGTARGTMTILKRLAEGTAVSKAADA -AMMDVLRAQKF-NNGIPAGLPEGTPVAHKTGSFA-GVYHDAAVVEPAGRAPFVLVVMTRH -VPDDDPKARELAAEIARIAYRH- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013B028F5 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTRR----------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum CTI-1 TaxID=1204474 RepID=U7TE06_FUSNU --tEWKKEIEKIISQVEGSVCINFYDLAKNTGF-SIDGDKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGKELRLKETFLGRKMMDIEAR-KNGYDNYTCADDISSLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLLSDIKIAHKCGDLDN-LENDGGIIWLGNKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. animalis F0419 TaxID=999414 RepID=H1HH47_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVF -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGRELDLKETFLGRKMMDIEAR-KKGYDNYTCADDISLHLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Erythrobacter flavus TaxID=192812 RepID=A0A3T1CJB1_9SPHN ------------------------RDIEGGRTL-HFNGLELFPQQSVSKLWVAMTALDEVD -AGRLDLSEMVAIRTADLTVHQPIRDIVRRDGSDYAELIERAITESDNTANDRLLRRVGGA -EAVQDFLDTHGLASIRFGIDERSKQSSYLADPIDGAPPVALVEALARLQRGELLSAGSTG -LLLGTLARTKSGPQRLKAGAPEDWIVRHKTGTGQQSGYNDIGLFTAPSGRSYAIAVMIAR -TREPTPVRMEMMQQVVRAVAR-- ->[subseq from] Class A beta-lactamase n=2 Tax=Vibrio TaxID=662 RepID=A0A2K1CLW1_9VIBR ---SLESTIATLEEETSSRIGVSVWDTHSNERW-DYRGYERFPILGTAKVFVCAAMLDAIE -RKTLNKDATITIKPEELSSYSPATQHWVEKPIDLTTLCEAATLEGDNTAANVIMRELGGP -QTTVLFLRSIKDTKTYLTEYFPTDSSL----RGNSSTPNTMVLNLRNILEGDKLNYGARE -QLKTWMKNIKRSKSKVFPTIPEGWSIAERRGFARD-SRAELFVIWREGYQPVYVGIYIKD -YDLSIQASEQLLTQVAQLILREy ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=A0A0M4G5W7_9BACI ---SLQQKIESYIENIDATFGIYIKHLGTNEEV-NIQENQLFQMASVCKVPILATLYEKVY -KGEIDLQERIKLVEEDYVPGSGVFQAMDYGVPTIKDLATMMIIVSDNLATDKVLSIVGGA -DRVQDRMHQLGLSNIYTKHTIWELLSFQDSTENNVSSAKDMSLLLEKIALGEFVSAECSS -DIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDAGIVYLPDKGEFVITVYSVG -SSLE-YKGDEPIARIAELAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. R-22-1c-1 TaxID=2487040 RepID=A0A3M9MCQ7_9BACT ----LREEVVAELGKQKGTFAVAFKDLKTGQEL-LINEHESFHAASTMKTPVLIEAYKQAT -QGKFALTDSVLVKNESIVDGSPFSYTQLGQKRPLTELLYKMIIQSSNLATNIVIEKL-DA -KKVTQTMRELGAKDIQVLRGVEDTK-AYRQGLNNTTTAYDLMVLFEKMGQGKTVSKAASQ -EMINVLLDQKF-KDVIPAKLPTDVKVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKG -LE-DEKAGIAAMANVSEMIYRH- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000E311E68 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLDNMGDHVTRLDRW---------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. Soil745 TaxID=1736396 RepID=UPI00070EF482 --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVVHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKMIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacteraeota bacterium TaxID=2052317 RepID=A0A2W5XBI9_9BACT ---SLQEALADRIRRVPGTAGVYVRTMQSGPALfTYNTEESFPAASTIKMLIMLTAFHREE -TAPGSLQAPVRLRSSDFVGGSPYLARASAGEYTVAQLVTPMITLSDNSAANALITHF-GF -DAINASARRAGLSNTYLRRHFLDYS-AIVHHHENVTTAGDMGRLLFSLERGAVAHPMFCR -RMVAIMLHQTD-RDKIPAGLPAGTPVANKTGEVD-GVRNDIAIVDPFGDSPFVLTVFTKN -LS-SYELARRAIAAIASDVF--- ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A2A8FSL1_9BACI --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLM-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKMIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E2ALY4_9CHLR -------NIEKAIFRVNATVGIAAKHLATGREI-LQNANDTFYTASTFKVPLIVALFRLVD -QGKIDPSERIKFSDSMRVPGSSILKVMGAGLPTIHDLAMLMIIVSDNTATDLIFDRV-GK -EFLNSTITEMGLSNTRIPMTTRELLYGFQEDKSDVSSPSDMSKVLELIHSGGFLSDQSSE -AVLNILLRQQL-NNVIPLLLPSGTKSAHKTGSYH-GVRCDVGIVYGESG-PYTVAIMAKG -ASGISLETDLSLARVSRAIYDEf ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2EBT5_9BACT ---NLTKRLKNLASKYSLEPGIFIWDISSGQYV-NINADKEYPTASIIKIPILFQLYKRAE -MGLINLNEKMSLQEYYITGGSGFLQKPVGTDLSVYNLAQIMIQESDNTATNMLLSAVGGT -NGLNRVLRSWGFSQTHMSDLLPDLYGT------NVSTPKDIGTMLYNIDNPDFLTLKSRA -NIVNIMSHVKN-RFLIQAGLPSNAEFIHKSGDIGS-MLGDAGIVMLPDGRKYVIVIMVKR -PW-NLYSAKEFIIKASEITYNSf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A4Q6F6B6_9PROT -------QIASLAEASRGRIGVAAIDLANGRTI-EVLGNQRFPMASTSKIAIAATFLEGVD -KGRWTLDQQFPLMVPQASKLSTKTAPVKPGRMSAREMIERMITRSDNQATDGLLAVVGGP -QSVNSWVRRAGIDGFSLDRDIATLVRATYIDKRDSATPLAMAQMLSGLHQGKWLSAQSRQ -VLIGAMERCITGKNRIPGKMPSNVLVAHKTGSLYN------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Melittangium boletus DSM 14713 TaxID=1294270 RepID=A0A250IRM9_9DELT ---------ERIAQVKGASVAVAYRDLGDPKDSlDLEADRSVHAASTMKVAVMLEFFRQVD -AGSLSLDMAPVLTNQSIVDGSPFAHERMGQPVPVRELVERMITRSSNLATNAVIARV-DA -KRVTKTLRALGARRMTVLRGVEDGK-AYAKGLNNTTTARDMAVLLSAIERGMAASPASTQ -AMRTILLAQEL-NQEIPAGLPAGTPVAHKTGQIS-GVLHDAAIVYPPGRKPYVLVVLTSG -IP-DEQVARALIVDVSRMVYAH- ->[subseq from] serine hydrolase n=1 Tax=Tuberibacillus calidus TaxID=340097 RepID=UPI00041FF742 --eKLTRCIEKWINEAGGTWGIVLEDLNEGVRW-EHNEDRLFYAASMIKLPIMAAVFAAAS -RGDFRLTDSLTMKKDDIVGGSGVLQHLSPELLPIYDLVTLMIIQSDNTATNMLIDLV-GF -QEIRNAMQNLGMEDSTCFTKLMTVPVERPG--RNMVTARDLNRLLKKLATGQFVSLYACE -HMIDIMKKQQF-RDCLPSLLPDDWEFANKTGWVT-GIRHDGGILYVGERA-LAITVLSES -V--DDRQAKATMGKIGRAAYEY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9DQ62_9BACT --------------ASGAEVAVALRTLDGRDEL-FIAADQSFHAASTMKIPVMIELFTQVQ -AGKVRLDEPLAVKNESIVDGSVYQYKAVGQTMTLGRLCEAMITVSSNLATNLLIDKL-GV -ENIRRTVHSLHADGMQVRRGVEDGKA-FAQGINNTTTARALLILLEAIAKSEAVDPASSH -AMVEILKRQKF-NEAIPAGLPAGTPVAHKTGEITK-IHHDAAIVYGPRA--YVLVILVRG -LAE-KERSAALMAEITKLVHQ-- ->[subseq from] serine hydrolase n=1 Tax=Bryobacter aggregatus TaxID=360054 RepID=UPI0004E1C564 ---KMHDRIVAYDARMDGALGVAIIDLTTGTQW-SYHGKLVFPTASAIKVPILMEIFRLRE -LGQLHFNEKVTLQPAEAVGGSGVLQERLRNGLSVEEIVREMIASSDNTATNWCIRRV-GM -AGVNHTMAQMGYQGTRLQRIMIDQAAA-TRNEENVSTPEDMADMLRVIYEGKAVNAKASA -EMIAMLKLVKA---GMRRAIPPAIEVASKPGELV-GVRTETGIVYLKGR-PFVLAVMGTY -LNES----DSPIEAVTKIVFDCf ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. OL1 TaxID=2517243 RepID=A0A4Q9TZ05_9BACI -----EQRITTLIQESPYNIHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE -KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYELLVWMIITSDNTATNVLIDVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLTPTYNK -LVINILSRQRI-HDSLKRYLVEDVRLAHKTGGLNT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] serine hydrolase n=2 Tax=Enterobacterales TaxID=91347 RepID=UPI0011AE1BC9 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPTR------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0011583522 ------------------------------------------------------------- --------------------------------------------------ANLLLTTIGEP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus sp. YR326 TaxID=1855296 RepID=A0A4R7U981_9BACI -----KQTITQILQKAPYKVHMFVKDCKTEHFYiSEKIEDTFSSASLIKVPILLAVLNYVE -INNLSLEQEIKIAPEEWVDFSVISEQRLEL-STIYELLVWMIITSDNTATNVLMDFL-GM -DTLNQYFREIGLLQTTVQRKMMDFER-LANGFDNTTSARDMALLFSRIYRRDLLSSAFSD -LTINILSRQRV-HESLKRYLVDEVKLAHKTGGLDT-VDHDVGIVYSSSGD-YLIGVFITE -VTN-NDHARQLIGRISKVVYDY- ->[subseq from] Imipenem-hydrolyzing beta-lactamase n=2 Tax=Planctomycetes bacterium I41 TaxID=2528024 RepID=A0A517U393_9BACT --rQMQARLQAIADGVDGTFGLVVADLAGQHRF-EVNADRQFTQASCIKTPILLEVLKQAH -EGKLQLADRRWVEKQDKTGGSGILAELGDRTLSIEDLCVLMIVMSDNTATNMLIDQI-GM -ENVTATMALLGCEQTVLRRRMMDAAAA-ARGEENLSTPADAARILRLLHEGTFVNREVSN -HALSILRKLKSG--AIRSTVPQSVSVAFKPGELP-GLLTEWALVELPER-PYIVVVMGTY -NPSTDDDLDAAMKQVGKEAYKFf ->[subseq from] Serine hydrolase n=1 Tax=Aureibaculum marinum TaxID=2487930 RepID=A0A3N4NIW5_9FLAO --eNLEHTIRTQIDSINGTVAVAYYNLSDPKDSlFINVDENFHAASTMKVPVMIELFKQAN -EGKLNVNDSILLKNESIVDGSIYSYKHIGTKVAIKDLIHSMITVSSNLATNVLIELV-NA -KNVTATMRNLGAKNINVLRGVEDIK-AYNKGLSNTTTARDLMIIMKAIAKNKAGSKADSK -AMIDILKDQQF-KSVIPKHLPNSVTVAHKTGSIT-GVHHDAGIVYLPDGRSYVIVLLSKE -LK-DFEKGTEQLAKISKTIYNY- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix parasitica NIES-267 TaxID=1973488 RepID=A0A1Z4LIM0_9CYAN ---QLYSQVKSLMSRYSLDPGMFFLDLETGDYL-DINGEKAFPAASTIKLPLLVALFEEVD -AGRVKLNETVVMRRDLMTGGSGTMRKRPGTKFGLLETVTKMITISDNTATNMVIDRLGGK -ARLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSPKDLARVGALISNNLILSSSSRA -KVLDIMHRVRN-KAYLGSGIGKNAKFANKTGTLGI-VLGDTGIVTMPNGKRYLAGMIVRR -PFRD-RRAKSFIKQVSRIVYGH- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. BN140078 TaxID=2607653 RepID=A0A5B2VRL5_9BACT ---SLQQQIADTLAQHAGVFAVAFKDLASGQEL-LINAHESFHAASTMKVPVMVEVFKQAK -AGKFSLSDSVLIKNESIVDSSSFQYTHIGERWPLSSLVYDMIIMSSNLATNIIMEMV-TG -RQVTQTMRQMGAKDIQVLRGVEDSK-AFEKGVNNTTTAYDLMLIFTAIAEAKTIDTPAAN -QMIKILLDQKF-NDIIPARLPQGVTVAHKTGEIT-GVRHDAGIVFLPDGRKYVLVLLSKQ -LQ-DTAGGVQAMAAVSEMIYK-- ->[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A163R3P0_9BACI ----NEQALLTLISSGEGNYGVSIYHFETKETF-EFQSDELFYSASIIKVPIMAAVFAHAM -EGKCSLSDQIRVREEDIVPGDGIIKHLSSNIWTIQDLIILMIIESDNTATNILIDRV-GL -DQINSYMKEWGFGQSHLHHKLQ-INAQREPGKMNVVTAYEMNEFLKKIAAGSVLSLNSCK -KMISIMKQQKM-NDLLPSLLPPNWEFAHKTGYVP-GIEHNVGLFYMPGQ-TYAISVLSNN -VP-NRSEPRRIMGEIGKLLYK-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Eisenbacteria bacterium TaxID=2212470 RepID=A0A538STU8_9BACT ----LEGGIRAVVAKSHGVWGISVRHVERHESA-GVRENERFNMASVFKVPILVELFHQAS -QGKIALDERVEWKDPGRYFGSGVLQARPGLNPTIHDLATLMIIVSDNAATDQLLARV-GK -ANVNARLRALGLTKTSVDAGTREHTLQALRDCHNCSTPSEMSQLFEKIVSGLAGDSVGTN -DMLGILSKQQF-NQRLPRLLPVGIRVAHKTGTVTNPVVNDAGIIYLPNGEHVVVTAFSHG -TDKAFNDAEDTIAEIGKTVFDYy ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7UPH8_9BACL ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SFNEDQRFYAASVIKVPIMTAVFAEAY -AGKFALEDKIKLRAEELVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNTMQKTEMSNSHFYNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVDILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAAIFMAQIGNLVYHVy ->[subseq from] serine hydrolase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F850C3 ------------------------------------------------------------- ------------------------------------------------------------- -ARVRKVSQLLDVPVSRFRMPLEDAYTAYYASGVNSGRLDAYGELLALLVEGRALGRPMTD -YLLQVMERTATGTRRIKAGLPPDARFAHKTGTQRR-RICDAGLITTPRRAPVLVVACVRG -D-LSLERSESALQQVGAALC--- ->[subseq from] Serine hydrolase n=2 Tax=Acidovorax sp. Root219 TaxID=1736493 RepID=A0A0Q8T8F7_9BURK ----LQAELTQVAAQNTAGIGVYVRDLESGIAV-SHRGQERWYLASTVKIPVALAVLQAVE -RGDFTLDTRLRVRAADYVDGAGHTNAKPVGALSIRYLLEQMVIYSDNTASDMLIGLV-GI -RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVNGKVLHGAHTR -YLLGVMERVQTGVHRVQAGLPKTARFAHKTGTQR-ARTCDSGLVTVPGRDQRVIVVACTR -GELSSARSDRALRDVGAALC--- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sp. AR18-8 TaxID=1889781 RepID=UPI000826AC51 -----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE -KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMVHLYTRIYQQELLTPTYNK -LVIDILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodonellum psychrophilum GCM71 = DSM 17998 TaxID=1123057 RepID=U5BW92_9BACT ----------------DKGLEVSLLQQPTGEILfSMNAEKSVPSASIIKIPILMEFFRQIE -SKTLHLDQMYALEAKDKVGGAGELQNLEENSHSLEFLAREMIRISDNTATNVLIGLV-GM -ENVNLLMEELGLKTTRLNRYMMDFE-AIEAGKQNITSPAEINKLLSIILSGVELSTSSRE -SMLNMLLACAD-KSTIPGKLPEGTRVAHKTGTLSY-VRGDAGIIL--NQKPIILSIFVEN -FE-TLEQADEIIANIANLAFEAy ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. Leaf13 TaxID=1736211 RepID=A0A0Q6GXA9_9BACI --qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDESFQSASLIKIPMIIEGYRQSE -EKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH -DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -KILRAFDNQQL-RDKLPSLMGKGVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE -DMKSEDESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D4YMK2_9BACT ---------ARIAVEPGVQVGLAYIDLASGDTL-FLNADSSFHAASTMKVPVMVELFRRAN -TGSFRMNQGLLLVNQSIVDGSLYAYHRIGERVRVDTLLRLMITRSSNFATNTLITLV-GA -DAVTRTMRSLGAERIQVLRGVEDGK-AFEKGLNNTTTARDLGIILRAIEEGRAASPTATR -EMLGILMAQEF-NEKIPAGLPPGTRVAHKTGEIT-AVSHDAAIVYPAGRKPYVLVVLTRG -IA-DGVKSSKLIADISAIVYAH- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=A0A4S2FIH8_9BACT ---HIEERLATYIAAQDARIGVAVI-IDGRDTI-SVNGNRDFPMLSVYKFPQAMAVADYCM -KNGVGLSDTISIRGDEMKEWSPMRDRYGVGDLPLSELLEYSLRDSDNNACDILFRLIGGT -HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE -AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNGVNDAGYVFLPDGRGYAVAVFIAD -SACGMEETERMIADISDIIFQ-- ->[subseq from] Serine hydrolase n=2 Tax=Muribaculaceae TaxID=2005473 RepID=A0A3N2K939_9BACT ---HIEERLATYIAAQDARIGVAVI-IDGRDTI-SVNGNRDFPMLSVYKFPQAMAVADYCM -KNGVGLSDTISIRGDEMKEWSPMRDRYGVGDLPLSELLEYSLRDSDNNACDILFRLIGGT -HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE -AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNGVNDAGYVFLPDGRGYAVAVFIAD -SACGMEETERMIADISDIIFQ-- ->[subseq from] Uncharacterized protein n=3 Tax=Fusobacterium TaxID=848 RepID=X7SCK9_FUSNU --tEWKKEIEKIISQVDGKVCINFYDLNKNNGF-SINGNEKVLSASMIKLLILAELMKKNS -ENKFSLSNTIMIENSMKTGGDGILKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-KKNGYDNYTCADDISLLFKLIYQEKLINKETSQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Pseudoflavitalea sp. X16 TaxID=2716334 RepID=UPI00141F9E46 ---QLKQAITSTLAQSEGQYAVAFKDLGPGTAL-EVNGDTSFHAASTMKTPILIEVYKQAA -AGKLSLSDSILVKNESIVDSSTYSYTRIGTKRTLYELVYDMIIMSSNLATNIVIEYV-DA -KKVTQTMRDLGARDIQVLRGVEDSK-AYQKKLNNTSTAHDLMVIFDKIATGQAVDSAADQ -AMINILLDQKF-NEIIPAKLPKDVKVAHKTGNIT-GVQHDSGIVFLPDGRKYVLVILSKG -IK-DEKAAIENMARVSEMIYQY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Enterobacter cloacae TaxID=550 RepID=Q6WWY1_ENTCL ------EQIKQSESQLSGRVGMVEMDLASGRTLaAWRADERFPMVSTFKVLLCGAVLARVD -AGLEQLDRRIHYRQQDLVDYSPVSEKHLTDGMTIGELCAAAITLSDNCAGNLLLATVGGP -AGLTAFLRQIGDNVTRLDRW---------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A3A4K107_9BACT --eTLRQKLANEISQFKGEAGIVVKDLQTNRVI-YHNKDKLFPSASLAKIPIMAACFLAAE -EGRLKLVRQVALKDSDKLTGSGILKDTRHGAFTVEELIGLMIYDSDNTATNILTNMV-GI -DYLNNSFKTFGLKNTELSRRIADYKSR-DAGFENYTTVEDMALILEKIYRRVLVNKDISE -KCIKLLKLQRI-SDRLSKYLPVETLVAHKTGLER-GICHDVGLVFTSEGD-FLICVLTKH -SNSNSAPSKEFIAKLALYAYAYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-20673 TaxID=1830326 RepID=UPI0007BECFE7 --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QRKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A351I130_9BACT ---KMTAALDKTAVHYPGRVSICMRDLRTGKTW-MYHPDDLFPAASLIKVPILIAAFYKMK -DGQLSLEEKLPITRRNRVGGSGSLKWRPDGTLAVRELLIHMINESDNTATKMVLERL-GL -GYVQQQFPRMGLLYTGIYEEGMSIKGG-RVAHENYTTAREMTMLLEKIYKGEAVDKPSSD -LMMEILKKPKAVASRLAKGMPTGWEIAHKTGLLRQ-ACHDSAIFLTPNGD-YSLTVLTGQ -NQ-SYSQAKTFITKLAHVTFANy ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. GBPx2 TaxID=2716263 RepID=UPI001409429F ----AQKDWQDFMKQFPDHLDISLLQDETGEPLfQQHAGKRIPSASIIKIPILISLMEKVD -EEHMHLDSLYTLQASDKVGGAGELQHLPEGSITFRYLAEEMIRISDNTATNILIRTI-EM -DYIQHWLREYGYEDTQLNRIMMDFK-AIEEGRQNYTSPQEINDILIKLWNGAWLNENSRA -EIMHWLKGCAD-NSTIPSQLPAGTVVAHKTGTLDY-VRGDAGIILG--DKPLILSVFVEK -FD-SMEEAESAIGQIALKAFRDf ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. TaxID=1960881 RepID=A0A3C0UVJ8_9BACT ---SLKETIEVRLKTVEGEFGVAFKDLQTQETL-FINDHENFHAASTMKTPVMIEVFKQAK -AKKFKLTDSILVKNESIVDGSPFKYRQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KNANTTMRQLGAQDIQVLRGVEDTK-AFQKGLNNSVTAYDLMLIFEKIALKKVVNKKACD -VMIHILFDQKF-NEIIPAQLPTNVKVAHKTGSIT-GVQHDSGIVSLPDGRKYVLVLLSKK -LTN-PKEGVKVLADISRLIYE-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax avenae (strain ATCC 19860 / DSM 7227 / JCM 20985 / NCPPB 1011) TaxID=643561 RepID=F0Q209_ACIAP ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DCA41E ----LSDSLAAYVKQLPTRVSIATRSLTDSRKSfYYRADERVPSASVIKLPIMIEIMERVR -AGLLDLDKMHSLLDSEKTGGDGVLKTYPHQRVSYRDMLRLMLIQSDNTATNIFINEL-GR -DAINRRIRQLGLTKTQLNRVMMDTLAA-RQGRENYVTAGEMNVLLEKIYRKQVATPNLCD -QMIDILKQNED-TVTIPRLLPKGTVVAHKTGTLPY-VRGDAAIVYARSEEPFLLSVFVEG -VS--QFEAERIIGDVALVCHSYf ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=W1I967_9BACT ----ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD -KKGISLDTLVKINREKLDPWSPMMKDYSTSVLTVRDLLRYTLIQSDNNASNIMFKNILNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQN -FIKNTLTECKTGVDRIVAPLKDGVVIAHKTGSGYNGAHNDVAFIRLPNNKYYTLAVFVKD -FKGNEKQAAKIIARISGTVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax konjaci TaxID=32040 RepID=A0A1I1UN45_9BURK ----LERALAQAEASSGVRIGVHVRDLETGASA-SLHATEPWYLASSVKVPVAIAVLRGVE -RGDFTLDTPLTLRAADYVDGAGATNSRPVGALTVRYLLEQMIVYSDNTASDMLIGLV-GI -GTVNAVVQSLVPAGIGRITTLADVRRTYYAGGLNSGRLDAYADLLEALVAGRALDARHTA -YLLSVMERVKTGTQRIKAGLPAGARFAHKTGTQR-ARTCDSGLITVPARERRVLVVACTR -GEPSTARSDRALRQVGIALC--- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) TaxID=485917 RepID=C6XYR5_PEDHD ---ELSRRIKAETNKYNADFAVAYKDLGTGETF-LMNAKTNFHAASTMKTPVMAEVFKQAA -KGKFAISDSVVVYNQKSIAGGGLYYHKIGKKMSIENLLLLMITRSSNLATNILIDKV-GA -KNVNKTMRSIGAHDIQVLRGVEDGK-AFEKGMNNTVTAYDLMLLFEKIAKGDMVNKKASE -AMVDILMQQTF-RGIIPARLPKEVKVANKTGSITK-VLNDSGIVYLPDGREYVLVLLSRG -MEE--EAAKKTLSSISEYIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax sp. Leaf160 TaxID=1736280 RepID=A0A0Q5LHH0_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -RRVQALARALDVPQAQLQKTMDEAYARFYRSGDNTATLVAYGGLLESLVRGKLVNAEHQQ -LLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQHQ-RACHMGVIDPQDGQRAIVVATCAE -GLDEQKQAGRAFEALGRAITQ-- ->[subseq from] Beta-lactamase CARB-6 n=1 Tax=Verrucomicrobia bacterium ADurb.Bin118 TaxID=1852928 RepID=A0A1V6DM14_9BACT -hqKTEIRLREIAARTRGALGFVALDLTSGERF-ALNETLTFPQASAIKIAILMEVYKQAE -EGKFKLTDARRIARADKVGGSGILKHLGDDTLSLADLCVLMIVLSDNTATNLLIDLV-GL -ENINRTLDALGLPHTRVRRRMLDTAASWRGD-ENVSTPAEAARIMEILFKGEFQNRATCE -AILALLRQTQG--GSIQAALPAHIPVAFKPGGIA-GVTTEWAIVELPGR-PYVLVVMENY -GLE--TDADTAIKELAVVVHEHf ->[subseq from] serine hydrolase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=UPI00076B9CFC ------------------------------------------------------------- ---------------------------------------------------SALLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D15C6CE ---PLERALARVEADSGVRIGVHVRDLDTGASA-SLHGTEPWYLASSVKVPVAIAVLRGVE -RGDFTLETPLTLRAADYVDGAGPTNSRPVGTLTVRYLLEQMIIYSDNTATDMLIGLV-GI -GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQALVEGRALDARHTA -YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRLLVVACTR -GEPSTARSDRALRQVGIALC--- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-22058 TaxID=1581037 RepID=A0A0M1NPZ2_9BACI ---TIEHDILGLVETFKGRIAYKIEN-GIGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIRELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGEMIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacteraceae bacterium AT-5844 TaxID=1054213 RepID=H0A7X3_9PROT ---SAKAEIARIAAFAEGETGVAALHMETGEAI-GFGEHGRYPPGSSIKMALVLCIFAMVD -RGELSLDDMIEVDDVEMTSSGPLGGEFVHAGLSLINLIEVTITRSDNTATDVLFRLAGGP -AAVQAWLRDIGIDDFDVTLSMREALCDYQLSVRDHCTPLAMLELLRRLYQLDGVSARTRE -LLLPIMQRTPS-FNRIRARLPKGVVGGTKPGSGS-GTCSDVGFITLPGRGTFAISVQVKA -SPRSMAEREVVVADITRLIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. YS11 TaxID=2072025 RepID=A0A2I7Z1Y8_9BACI -----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE -KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM -EYLNVYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTQIYQQELLSPPYNK -LVIDILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Peptoniphilus lacrimalis TaxID=33031 RepID=A0A379C2D1_9FIRM ---KIKKHIEKIISESSGNICLSFYDLDDEEGF-SINEDKKVRSASMIKLLIMAEIMNQSK -NGKISLDTKIKVGKKDKVGGSGILKEFDCEHFSIKELMTLMIIVSDNQATNILIDLV-GM -DNINLMGKRLNLKSSSLQRKMMDIK-ALEKGRDNYISAIDVKVILEKIYRKTLVDEKSSE -LMLDILLRQHE-RQRLGRFLDEEVKIASKTGDLDK-LENDGGIFFLENKN-YILVVLIDD -AV-TNAMAQETIGKISKYIYDE- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus asahii TaxID=228899 RepID=A0A398AY73_9BACI --qSIEPKILELIETFDGRIAYKIEN-DRGESI-SYHEHEAFQSASLIKIPMIIEGYRQAE -NKDIYLNQPLTIPRNEVTRGSGVLHTLSDKVLTVEDLLTLMITISDNTSTNMMMTLL-TF -EKINQCIQELGLENTVLQRRMFDFKA-LKEGRDNTMSAADTVLCLKAIHTGDFLTKASQE -RILDIFEQQQF-KERLPAMMGKGVKVGNKTGSLR-GVMHDAAIIRSETET--VCAAVLTE -DMASEEESRQIISKIGKLIYDE- ->[subseq from] AMIN domain-containing protein n=1 Tax=Nostoc sp. NIES-3756 TaxID=1751286 RepID=UPI00082E1D11 ----LDFRIKQLMNCYSLSPGMFFLDMETGEYL-DINGEKTFAAASTIKFPILIALFQEID -AGRINPNETLLMRRDLMTGGSGTMQYKAGTKFSLMETASKMMIISDNTATNMIIDRLGGK -NRLNQKFHSWGLQNTVIRNLLGDFKGT------NKTSPKDLVRLAALVSNNKLLSTKSNS -QVMNIMSRCHN-RSLLPVGLGKGAKIAHKTGTLGR-VLGDAGIIQTPSGKRYLAGIMVAR -PFGD-VRARTFINEVSRLVYG-- ->[subseq from] Uncharacterized protein n=1 Tax=Oscillibacter sp. TaxID=1945593 RepID=A0A350TJS3_9FIRM ----LQDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ -SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNIATNLIIDAV-GM -PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSSDMSE -FALDLMKGQHD-DAGLLEGLPVGSVFAHKTGTLD-GVFNDGGIALAPN--PYVMVVLSSD -AERSQ--AQACMVDIAQAA---- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0004177EA6 --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM -ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LILDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobium chinhatense IP26 TaxID=1346790 RepID=W1KKU6_9SPHN -----------LGTSFKGKVGISVRNMDEGWMV-SFNGGRMLPQQSVSKLWVAIAVMDAVD -HGALSLSDPVTVRRSDLTVHQPIRPLVTKAGTTIGKLLEMALTRSANSCNDVLLWKVGGP -EAIRAMLKRKRINDVGFGPGERKLQARYLANPYDGASANGVTLGLMLLKQGKLLSKSSTR -HLLSLMRASRTGPLRLRSGLRNGWTLAHKTGTGQTTGYNDVGILVSPEGHRYAVAVMIAS -TRAPIPARMRLMGDVTRAVIR-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus butanolivorans TaxID=421767 RepID=A0A0M0ESF2_9BACI --qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDESFQSASLIKIPMIIEGYRQSE -EKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GN -DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -KILRAFDNQQL-RDKLPSLMGKGVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE -DMKSEDESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax citrulli TaxID=80869 RepID=UPI00069803A9 ------------------------------------------------------------- -----------------------------------------------------------GS -QRVQALARTLQVQKDDLKKTIEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE -DMDEMRQAGRLFEQLGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter tibetensis TaxID=512763 RepID=A0A0P0CIT2_9BACT -----REEVLAELGKQKGTFAVAFKDLKTGEEL-LLNEHESFHAASTMKTPVLIEAYKQAS -EGKFAITDSVLVKNESIVDGSPFSYSQLGQKRPLSELLYKMIIQSSNLATNIVIEKL-DA -KNVTQTMRDLGAKDMQVLRGVEDTK-AYRQGMNNTTTAYDLMVLFQKMALGKTVSKSASQ -EMIKILLEQKF-KDVIPAKLPQEVTVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKG -LE-DEKAGIEAMANVSQMIYQH- ->[subseq from] serine hydrolase n=1 Tax=Acinetobacter seifertii TaxID=1530123 RepID=UPI0012504791 --nSVQQQLEALEKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPT------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=2 Tax=Bacteria TaxID=2 RepID=UPI0009906C8C ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A350D5P7_9BACT --------ILKRISNLRGQTGIVVEDLETGWTF-IHNEEQPFPAASLVKIPIMVACFKAAG -EGLLDLSGKYVLKRKDRVGGSGRLRRMRNGRFTFAQLIDYMVTESDNIACNILIDRL-GF -DYINNVFDELGLKKTRLNRKMIDFAAR-DQGLENYTSAAEMTGLLERIYHRCCYNAVISD -QCLAVLKRQKI-NDRLPRYLPKEVTVAHKTGLEKE-VCHDAGIVFTPNGD-YIITVLVHT -W---------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus caseinilyticus TaxID=1503961 RepID=A0A1H3UGY3_9BACI ------GEITKIIGEAAGSFGVAIKHVESGQEV-IINGEKQFEMASVFKLPVLVALLTNAA -PRAVSLDTRMEIRQNDRVPGSGIIKELDEGLMTIRDLATLMIIVSDNTAADMVLHMI-GK -ENVNRKMKELGLENIVVRQSCWELLTMENTRQGNRATVTDTNALLEKIVTRRI-EVTASK -QIIDILSRQQY-RQRLPSLLPPATKTANKTGTIGT-VVNDAGILFLPDHKGTLIITVFSE -GNRTLAAGENVIAKIAKTAFDHy ->[subseq from] Beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A412N9W8_BACVU ----ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD -KKGISLDTLVKINREKLDPWSPMMKDYSTSVLTVRDLLRYTLIQSDNNASNIMFKNILNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQN -FIKNTLTECKTGVDRIVAPLKEGVVIAHKTGSGCNGAHNDVAFIRLPNNKYYTLAVFVKD -FKGNEKQAAKIIARISGTVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides salanitronis (strain DSM 18170 / JCM 13567 / BL78) TaxID=667015 RepID=F0R526_BACSH ----LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQALAICNRFD -QDGLSLDTSLTIRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV -AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD -FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVSYALAVFIKD -FKGNESQASQVAARISAAVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. CAG:617 TaxID=1262933 RepID=R7PDW2_9BACT ---GLAEQIVELTTRCRAQTGVAVIM--GRDTV-CVGNDTHYPMMSVMKLPLAVWVVDSLL -HHGCSWRDTVEVDSASLLPYSPMRQQYPRGGFSMEQVLNYSLQLSDNNACDWLLHRSGGP -RAVERFLRRRGLTNISIQFTEDDMHVDPRRAYGNWTTPLEMARLVAMLLEGRLTDERGQE -WLRGSLLQCQTGQNRLARPLETGAAFGHKTGTSDRDAMADAGFVRLPDGRKYVIVVFVKD -AAESDARVEQLMADVSELVYR-- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. LJ137 TaxID=2293253 RepID=UPI000F489070 ---DVQQRIEALCDAAGGSWGIMLMDLDNGSSW-GMNETQPYTAASIMKIPIMATVLQAHE -SGKFQLGDKLILKKEDLVGGAGVLQHMTPGTLTVYDLMMLMIIQSDNTATNILVDLV-GI -KTIQQYLKVHGFEGTSFYNKLMIVPAK--RKGPNLITAVDMGRLLTEIAQGHMISLQASE -RMIDILKKQQL-QDCLPALLPEQWEIAHKTGSVQ-GILHDVGILYVGQRK-LVAAILSQG -LDK--LAAQSVIQKIGLELYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus psychrotolerans TaxID=126156 RepID=A0A1I5Z3R3_9BACI ---NLQQKIESYIDTVDATFGIYIKHLGTNEEV-NIKEHQLFQMASVVKVPILVTLYEKVY -KGEIDLQQRIKLVEEDYVPGSGVFQEMEYGIPTIKDLATMMIIVSDNLAADKVLSILGGT -HQVEEKMHQLGLSNIYTKHTIWDLLSFQESTENNVSSAKDMSLLLEKIALGDIVSEECSR -EIREILFKQHF-QQRIGGLLPRNKKVANKTGSLGT-MFNDTGIVYLPDNGEFVITVYSVG -NSLE-YKGDEPIARIAEIAYQHf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6FG45_9BACT -------------------MGVAILDLSDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSQIMSGLTPGVVTNRDLAQFMVAVSDNAATNVLIDHV-GM -QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVSTPQEMARLLEMIYKGKALNQELTG -DLIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GVRTDSGIVFAKNR-PFAISVMTTY -DR-DEKAAERAISEVALEAYRYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI00119D4B4E ---TIEHDILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE -RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI0011A3B828 --qTIEHDILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLENTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE -RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EBJ0_9BURK ---PLERALARVEADSGVRIGVYVRDLDTGASA-SLHGTEPWYLASSVKVPVAIAVLRGVE -RGDFTLETPLTLRAADYVDGAGPTNRAVGTPLAVRYLLEQMIIYSDNTATDMLIGLV-GI -GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQALVEGRALDARHTA -YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRVLVVACTR -GEPSTARSDRALRQVGIALC--- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum subsp. animalis 4_8 TaxID=469607 RepID=R9REA2_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQKKLINKETSQ -LMLDILLRQQQ-GERLQRYLSSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase class A n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=A0A1T5IQT9_9BACT --eKLGKNIASVLGQQSGVFAVAFKDLTTGEEI-LIDERESFHAASTMKTPVLIEVCKQVV -AGKFSLTDSIVLKNESIVDSSVFTYNHLGEKRSISSLAYDMIIASSNLATNLIIELV-DA -KNVTQTMRDLGARDIQVLRGVEDAK-AFDRGLINTTTAYDLMVIFEKIANGEAVNPEASQ -IMIGILSDQKF-NEIIPAKLPKDVKVAHKTGNIA-GVNHDSGIVFLPDGRKYIVVLLSKE -AK-DEKAAIAAMASVSEMIYSY- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=UPI000FF85698 ----ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD -KKGISLDTLVKINREKLDPWSPMMKDYSTSVLTVRDLLRYTLIQSDNNASNIMFKNILNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAILMNRLFTESLISNEKQN -FIKNTLTECKTGVDRIVAPLKEGVVIAHKTGSGCNGAHNDVAFIRLPNNKYYTLAVFVKD -FKGNEKQAAKIIARISGTVYS-- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI0006C9EF28 -----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE -KNKLSLNSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIEVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRIYQQELLTPTYNK -LVINILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Serine hydrolase n=1 Tax=Gemmata obscuriglobus TaxID=114 RepID=A0A2Z3H5M8_9BACT ---DLESRITPLVKEHKGKVAVAVKHLKTGEEF-YLNADEPMPTASLIKLPIMVEAYWQAK -EDKIKFDKPVTLAKGDKVPGSGILTPHFSEGFPLKDAIRLMIVYSDNTATNMVIDQI-GL -PATGERMAQLGLKNTKVNAKVFKPETFGKKYGLGSTTAKEAVRLLELIDAGKVVSPEACK -EMLGHLKACDD-KEKLVRFLPAGTVVAHKSGSVD-ASKTDAGIIYTKGG-PIAVCVLTDA -NEAADNAGQVLIGKVAKEVFDHf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides reticulotermitis JCM 10512 TaxID=1445607 RepID=W4UWF3_9BACE --------------------------------------------MSVYKFHQALALANYME -QRNLPFETILGITQSDLKPYSPLRDQYPNGGMSVAELLKYTLQQSDNNACDILFRYQGGT -GAVNRYIHSLGITDCLISATEEEMHQDLERCYQNWTTPVAAAGLVDLFLRKPLFGAAYKD -FIYQTMVECQTGKDRLPAPLTKGVIIGHKTGTGGLNGTNDIGFILLPNGHRYSIAVLIKD -SEENPQATSGLIGEISRIVYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium 13_2_20CM_2_66_5 TaxID=1805203 RepID=A0A1Q7AVU0_9BACT ----LKARVQARILQTPARVGLYYRDLTTGDSL-TVGSDVRFHAASTMKVPVMIQLFRDRD -AGLLSLDDSVTITNTSIVDSSPYRYKRLGQRASIRQLIELMETVSSNLATNLLIAKV-DA -KRANATAHALGADSILVLRGVEDD-KAYRAGLNNTTTARDLGMLLAAIANGKAASAASCR -EMLAILGRQQF-NEGIPAGLPPGTTVYHKTGWIGQVVYHDAALVEPPNGGRYVLVVLTGA -IQKD-ADAHAAVRDLSKLVFD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax radicis TaxID=758826 RepID=A0A561D152_9BURK ----LQAELVQVAAQNTAGIGVYVRDLETGIAV-SHRGMERWYLASTVKVPVALAVLQAVE -RGDFALDTKLRVRASDYVDGAGQTNSPVGTALSVRYLLEQMLIYSDNTASDMLIGLV-GI -RAVNALVEQLVPRGFERITSLADVRRAYYAGGLNSGRLDAYADLLELLVNGKIVNPEHTR -YLLAVMERVQTGVYRVQAGLPKAARFAHKTGTQR-ARTCDSGLVTVPGRDRRVIVVACTR -GELSSARSDRALRDVGAALCQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus choshinensis TaxID=54911 RepID=A0A0Q3SY28_BRECH --eQLRQKLSDLLAKAQGSWGVVVEDLDHGTRF-EHRAEESFIAESVIKVPIMAAVYAAAD -RGQFTMDDRLSLRKEDLVKGSGLLYTLSPGLLTIRELVTLMIIQSDNTATNVLIDLV-GK -ERIDQTMFELGMQQSKYSRKLMIYPVD--ISENNTITACDVSRMLGRLATSKFLSHRACE -EMIGIMKKQQV-RNGLPSLLPTDWEIACKSGWDT-GRQHDVGVLYVGDRR-FSIVALSQN -VQ--AEAALEVLGQLGKEVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5KLV7_9BACT --kKLETRVEEIAGRLDGVMGAAILDLTDGRIL-LRNADRVFPTASSIKIAVLLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSQIMAGLTAGVVTNRDLAQFMVAVSDNAATNVLIDHV-GM -QNVNATLRSLGLTKTMLRRKMIDIAAARRG-DENVATAQELARLLEMIYKGKALNQELTG -DLIKQLKTLKK-DSYLSYELPADVELADKPGTLD-GVRTDSGIVFARNR-PFAISVMTAY -DR-DEKAAERTISEVALEAYRYf ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Escherichia coli TaxID=562 RepID=D1LFC7_ECOLX ----------------------------------------------------AAAVLKQSE -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGTTT------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A2X0XS56_LYSSH -----EQRITTLIQESPYNVHLFIKKLTTNQLIiSHQLETSFSSASLIKVPILLALLSYIE -KNKLSLDSTLTISPTDWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTQIYQQELLSPPYNK -LVIDILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGCLSKVVYDQ- ->[subseq from] Beta-lactamase class A n=1 Tax=Sediminibacterium ginsengisoli TaxID=413434 RepID=A0A1T4K2J1_9BACT ---TLTQKIQQLLSGQQGVFAVAFKDLATGETI-LINEKTMFHAASTMKTPVMIELYKQAA -AGTFSLQDSALVRNESIVDGSLYRYRREGERLSLNELIYQMIIRSGNLATNILIEIL-DG -KKITATMRELGAPDIQVLRGVEDQK-AFDQGLNNTTTAYDQMKIYEALANGKAVNKDASD -AMIRILLDQQH-NTVIPALLPKDVKVAHKTGSITS-VHHDAGIVFLPDGRKYVLALLSAK -FT-SDKEATGAMARVSQLVYRY- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI0004FF95F4 -----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVIAYTE -KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE -LVIDILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN -VT-DNDLARQLIGRLSKVVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8CMB4_9BACL ---SLSPSIAPLLEESGGEWGVYLEDLHTGEQL-SFNQNERFYAASVIKVPIMAAVFAEVS -AGKFALETIIRLRQEDQVGGAGILQHMTPGSWTVQDLVTLMIIQSDNTATNMLIDLV-GK -ESIRSIMQATEMTNSHFYNKLMIVPAQVEG--YNEVTAADLGNHLRYLAKGKVISYDSCA -RMMAILKQQQH-RDRIPLHFPPSWELANKTGSVTN-ITHDIGILYVGSSA-VTICVLNKG -LP--QKAAVQTIASIGKLVFDLy ->[subseq from] serine hydrolase n=1 Tax=Numidum massiliense TaxID=1522315 RepID=UPI0006D57C51 --eQLKQTLEQLMEKAGGMWALVVDDLDRQTQW-AHNEEELFYAASVIKIPIMAAVFAAAA -RGNLRLSDRVTLMREDIVGGAGVLQHMTPGILPIVDLLTLMIIQSDNTATNVLIDAV-GK -PFIRETMRELGMSRSEFHHKLMIVPAKTKG--YNVITAADMSCLLARLAHGKFLSRHACE -QMIAILKKQQF-RDCLPAHLPEHWELAHKTGWVT-GIRHDVGIFYVGNR-CMTVALLSRD -VD--DFVARQTMAAVGRHIYEY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI000C265912 ------------------------------------------------------------- ------------------------LEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=1 Tax=Mycobacterium tilburgii TaxID=44467 RepID=UPI0011820C68 ------------------------------------------------------------- -----------------------------------GQLCAAALQRSDNTAANLLLSAIGGP -PAITDFARSIGDELTRLDRWELELNTAIPGDLRDTSTPRALGTGIRKLLTGTVLGQAQRG -QLEQWMRGNTT--SSMREDLLPGWSSADKTGTGDYGSTNDVGMVYGPAGQRILVSIMARS -QSPDAAALRPLIADVTRSVL--- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=UPI0001D0A9E7 --tEWKKKIEKIISQVEGNVCINFYDLNKNNGF-SVNGDKKVLSASMIKLLILAELMKKIF -ENKFSLSDTVMMANFMKIEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VG77_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GE -ARVRKLAQILGVTPTELLPDLDSAFESYYATHANSASLRDYGRMLAALQQGRALDAEGTR -YLLDVMGRVQTGRQRIRAGLPAGATFAHKTGTQYR-RLCDSGIVTMPSAPRVVIAACVRG -AT--GAAGERALRDIGAAVT--- ->[subseq from] Serine hydrolase n=1 Tax=Haliea sp. TaxID=1932666 RepID=A0A519HLL0_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GP -KRVDNIRRALNLQPGNLQATIDDAYARYYRTNVNSATLQAYGDMLEKLVKGQLLKPASMQ -RLFTDMKIDIYTNYRVQAGLPRSVKFIHKTGTQYR-RACHVGVINPQNNAANAIVVTTCA -ADDEQRQAGAVFQQVGRAVTK-- ->[subseq from] serine hydrolase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F8EEEF --eALGAQIERIDRGTPGELGVFVKRLDGGETY-RHGAERFWYLGSMTKVPIAIAVLQQVD -AGKLKLSDTVELQDADRIDVSRVVRERTGRRYTVDALLDRMLKDSDNTAANMLIRTV-GE -DTVQRAAQALGTQGFK-------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Comamonadaceae bacterium ALPHA2B TaxID=2502232 RepID=UPI0010F8EEEF ------------------------------------------------------------- -----------------------------------------------NTALVQVANAPLGP -GRVQAVQRALKLKDGDLQRTIDDAYDRYYRHDINSATLDAYGAMLEKLVRGELLQPASLQ -RLYAAMKLGTFTNHRLQAGLPRGEPFIHKTGTQYE-RACHAGVLRPQDRAHAVVVAVCAA -GMDEHKDVDAIFQQVGRAVAQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Tumebacillus permanentifrigoris TaxID=378543 RepID=A0A316DZR3_9BACL ---ALSEQLTKCLQAAQGTFGVAIHHFQSQETF-HYNADEVFFAASIIKVPVMAAVFDQAS -KGVLTMAETMTLRTEDKAPGSGILSNLSTGLISIWDLVVLMIIESDNTATNMLIDRI-GM -ETVQACMQEWGMEQTRIYNKLAVIPAN--LQHVNTISPREMTDFMIKLAESKIVSWKACR -EMVDILKQQKF-NDGIPSLLPPTFEMAHKTGWVRT-VENDCGLLYFPGHT-FAISIFTKD -VT-DKPATKRVMGEIGLHLYN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Novosphingobium kunmingense TaxID=1211806 RepID=A0A2N0HK34_9SPHN ----LQTALNDIAARFQGKVGIAINQAGCKWLV-GVRADEYFPQQSVSKLWVSLSVLDAVD -RGQMRLDEPITLRPDDQVVNQPLRWTVLDQGLPAQTLMQDSLSLSDNMANDKLLWRVGGP -DHVRMVLSERKIEGIRFGPGERLLQSKYVADPMDGATPAGIASALGRLGGGELLSEQSTA -LLLDIMAHSKSGPRRLKGGLLPGWKAYHKTGTGQQTGFNDVALVEAPDGTRYGVAVMIGE -TRLPNPARLEMMQAVSRALVA-- ->[subseq from] Beta-lactamase n=1 Tax=Stigmatella aurantiaca (strain DW4/3-1) TaxID=378806 RepID=Q098G1_STIAD --------------------AVAYRDLGDSRDAvFLEADTSFHAASTMKVPVMIEFFRQVD -AGVLALDQPIVLTNRSIVDGSPYSYEHLGRPMPASELLKRMITRSSNLATNSLIALV-GA -KRVTRTLRTLGAPSMTVLRGVEDGK-AYAKGLNNTATARDLATLLAALEQGKAASPRSTQ -AMRDILLAQEL-NALIPAGLPPGTPVAHKTGQIT-AVLHDAAIVYPAGRAPYVLVVLTRG -IA-DEQVARALIVDLSRSVHA-- ->[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf274 TaxID=1736318 RepID=UPI0009E8830F ---RLSAELERIDAAPDGRIGVYVRALSSGESL-SFRADQSWYLASTVKVPVAIAVLRGIA -RGAYTLDTPVTLRADDYVDGAGSTNSHAVGTLPIRTLLEQMIIHSDNTASDMLIGLV-GL -EQVNAVVTEVAPAGFGPITRLAEVRRAYYATGLNAGRLDAYGELLAQLADGRLLPPTQTR -HLLGLMERVVTGPQRIRAGLPAGMRFAHKTGTQR-GRFCDAGIVQPAGGATRVLVVACTR -GELSLVRAERALREVGAALC--- ->[subseq from] Serine hydrolase n=1 Tax=Caldilineae bacterium TaxID=2420332 RepID=A0A3M1FGV3_9CHLR ---NLRDELAAIIQESGAEMGVAIRHLETGEEI-NIHGDRVFPLASVFKIPVLVEAFRQIH -AGKLTLDERHTLTVTEKNLPSGVLVFFDDGLPTFRDLLTLMIIISDNTATDMVMHRL-GA -GAVTRTMHDLGLTDIHVPITVREIFDYSLGPDNNVGTPRALTQLLSMIWHGQIIDRAACD -AMLAILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GLRNDSGIIYVDDHNHVAVTVFSRW -DDEA------------------- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Acidaminococcus sp. CAG:542 TaxID=1262687 RepID=R7M167_9FIRM ---------------AAGPAQVYFTNLSTNQSL--YRGSETMTAASMIKVFILAKAYEDIQ -NGSLSRNETFTLTPDNVVGGAGVLQGRGYGSVSLQEALELMITESDNTAANLLIDRL-GM -DRINAYMQRHGYTHSVLRRKMMDTE-AMAAGRENLTSTRDIALLFKRLYQGKCVSPAQDR -EMLAIYKRQTD-NDSIPGDLPRGTVVAHKTGEVND-LRHDGGIVYTPNGD-YVLVIFTRN -YTP-YETMADLSEKIYQAV---- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus varians TaxID=1145276 RepID=A0A4U2YGB1_9BACI -----QPTIQRIIQEAPYKVHMFVKDFKTNDFViNECLDEAFSSASLIKVPILIAIFDYID -VCNIPINQVIAISPSDSVDFSVISEQRVT-SCTIYELCVWMITTSDNTATNVLIDVI-GM -EALNKYFHKIGLTHTQLQRKMMDFER-LAKGIDNITTARDMAHLFSQIYRQNLLSPVLSQ -LAIDILCRQRF-HECLRRYIVDDVTIAHKTGGLDT-VDHDVGIVYSHVQD-YGIGVFISE -VKH-NDVARQLIGRLSKVVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2G6Q4K1_9BACT --kDLDRQINEILAGQPGVYSVSYRDLASGREW-HFNADDRMHAASTMKVPVMLRVFQKLE -QENKSLNDALRVHNSSIVDGSAFAYQFLGKNVPIEHLVRLMIIRSSNLATNILIDWV-DA -KKVTELMVELGARQTSVLRGVQDLK-AFEKDMNNTTTSRDMLQILISCYQSELFTKTSRD -AMIQFLLDQEF-NDLIPAGIPANAKVAHKTGSISR-VHHDAALVMLPDGSSYGLVVFSRD -FGEERERVKQTIRNISSAVYQY- ->[subseq from] class A beta-lactamase n=1 Tax=Moraxella catarrhalis TaxID=480 RepID=UPI000EAA6877 --------------------------------------------------------LLLVD -KEKLDLNEKIIIKESDLIEYSPVCKNYFDENISISELCEATITLSDNGSANILLDKIGGL -TAFNQFLKEIGAD-MVLANNEPLLNRSHYGETSDTAKPIPYTKSLKALIVGNILSNQSKE -QLITWLINDKVADNLLRKYLPKNWRIGDKTGTGSE-SKNIIAVIWNENNKPYFISLFITQ -PHDGKNQKDEIMAQIGKEIY--- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C1YRB7_9BACT --eKLTAKIKQIVEQADAVVGVAIKDLRSGEQI-LFNEDEIFPQASSIKIHILSEVYKQAA -EKKFNITDIKQLPITARVGGSGILSSLGEKSLSIRDYCVLMIVLSDNSATNLLIDLV-GM -KNVNESLQKNGATKTKLQRVMMDIQAA-KEGRENISTPKDVLVILDKMYNGTLVNKQASD -DMLSIMKLDKD--GALKSGIAPDVSIANKGGDVE-GVRTDVGIIYLENN-PYSICVMTKM -LVH-NEDGSKIITDVSHEAFNYf ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus raoultii TaxID=1776387 RepID=UPI0008D95A8C ---ELKAKIENYIEENKGNICLSYYDLDKGEGL-SIKGEEKVPSASMIKLLIMATLLKEVR -EGKISLEEKIKISKDEYCGGSGILKELDPGHLTIKELMTLMIIVSDNLATNILIKLL-GM -KKINEMGLELGLKNTFLGRKMMDGEAK-SLGKDNFTSADDIKNILKLVYKKELVDEKSSD -LMLELLLSQHE-RERLQRFLGEEVKIANKSGDLDF-LENDGGIFFLEHK-TYILVILVSK -AS-SNYEAKEIIGKISKFIYEE- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium xiamenense TaxID=1297121 RepID=UPI0012B8A053 ------------------------IQGAEGEILaEYEPDKGVPSASIIKIPILLALLEAVE -NEELSLEDRYHLRNQDKVGGAGELQFEPDGSLTYRTLATEMIRISDNTATNILIDEL-GM -ERIQGWLNERGFTATQLNRKMMDFA-AIEQGKQNYTSPAEINRILLMLLDSKSVSAETAA -SARQLLTACAD-RQTLPALLPKNLEVAHKTGTLDY-VRGDAGIIFG--KRPLVVSVFVEH -FQ-EIEEAEKIIAEIGRLAYEIy ->[subseq from] serine hydrolase n=1 Tax=Acidovorax avenae TaxID=80867 RepID=UPI000D152DAE ------------------------------------------------------------- -----------------------------------------------------------DP -QRVQALARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I3WFG3_9BACL ---SLSTQIAQLVENAGGEWGIYLEDLQTGETL-AFNEHKRFYAASVIKVPIMTAVFAEAY -AGNIALEQKIKLRQEDLVGGAGVLQHMTPGTLTVQDIVTLMIIQSDNTATNILIDLV-GT -ESIRAAMQKTGMANSQFYNKLMVVPAELEG--YNELTAADMGSHFRYLASGKVISYDSCL -KMMAILKQQQH-RDRIPFHFPPKWELANKTGSVTH-ITHDTGVLFVGPHA-VTICALNKG -L--EQIPAAQTIAEIGRLVYNLy ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. AFS017274 TaxID=2033488 RepID=A0A2A8TN97_9BACI ---TIEHDILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLENTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE -RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4WW84_BREBE ----LFAQISSLIKDAGGEWGIFFEVLQTGETL-SINEDQRFYAASVIKVPIMTAVFAEAY -AGKFAFEDKIKLRTEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNMMIDLV-GT -ESIRNAMQKTEMTNSQFHNKLMVVPAELEG--YNEVTAKDMGSHLRYLATGKIISYDSCL -KMVAILKTQQH-RERIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAANVMAQIGNLVYHAy ->[subseq from] PG_binding_1 domain-containing protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7L3Y4_9PLAN --kSLRQKLSSLLKTHEGHVAVAIKHLATGERF-EFEANRAMPTASLIKIAVMVEAYRQAD -AGRIDLEQRITLLAGDKVPGSGILTTHFSAGVSLRDAIRLMIAYSDNTATNLVLEQI-GI -RSTSKTMEKLGFPNTKIHAKVFRRDTRSKRFGLGSTTALETVQLLEQLYRKQLASPSASD -AMLKHLENCQD-RTKLRRFLEPHITIAHKTGSLAT-VRTDAGIISSPSG-PLVVCVLTSE -NKTEENAGEILCARVAKITCAHf ->[subseq from] Beta-lactamase class A n=1 Tax=Larkinella arboricola TaxID=643671 RepID=A0A327WPN5_9BACT --kELRQQIERELSQQPGTFAVAFRDLKTGQEL-LIREHENFHAASTMKTPVMIEVYKQAA -QGRFSLSDSMLIKNESIVDGSPYSYTRVGTKRPLSALVYDMIIVSSNLATNLVIELV-DA -RKVTQTMRDFGAKNIQVRRGVEDKK-AFDQGLNNTTTAYDLMVIFDKMASGKAVSPEASA -DMIRILLDQRF-NTVIPAQLPNDVKVAHKTGSIA-GVHHDSGIVMLPDGRKYVLVLLGKD -LN-DESASVRSMATVSRLIYDY- ->[subseq from] Beta-lactamase n=1 Tax=Peptoniphilus sp. ING2-D1G TaxID=1912856 RepID=A0A090HZ88_9FIRM ----LKLKIENIIRRTKGKVCLCFYDLKENKGF-GINELQKMRSASTIKLLIMAELMRRVK -NKEFSLSDKIAVTKDNFTGGDGILKELEYHHFSLKELVTLMIIVSDNEATNILIDLL-GM -ENINKLGKNLKLKEADLQRKMMDSE-ALAKGYDNYICAEDLKTILQKIYEGKLINKKSSE -IMLDILKRQTQ-GERLQRYIAEELTIAHKSGDLDN-LEHECAIIFLEDMD-YIIVVMTDD -MN-SNLEGREIIGKISKTIYDE- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Elusimicrobia TaxID=1797919 RepID=A0A1F9S063_9BACT ---AMTADVEASARRYPHRVGIYIKDLHHNLEW-SYHADDLFPAASLIKVPVMCGVFEKIH -RGELSLNSQLTLRRRTRMGGSGSLKWAREGSYTVRRLLEKLIHESDNSAMMLLIDEV-GM -GYLQRFFPSMGLVYTEIYPDGLRLTSG-SVRYENYTTPREMGGMFEKMYRHQMVDQFASE -LMLDILKSNPS-RSRLAKELPVGWELAHKTGLLRR-ACHDVGIVFSPQGD-YVIAVLTGR -NQ-SYTAAKDLIINLGKTTYKYy ->[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera sp. GP187 TaxID=1882752 RepID=A0A1N6JE71_9BACT ----LERTLRAIVEP-AGEVAVVYTNLADGEQV-FIKGDERIHPASTMKVPVMMEVFRQAE -LGTLALDGGIRLKNDSIADGSRFTYRHLGEERPVRELVRLMITESSNLATNLLIERV-TA -PRVSELMKAMGAGDVRVLRGVED-NRAFERGLNNETTARGLATILQQLAARRVVSVKASE -EMLAILRGQKF-NEGIPAGLPAGVPVAHKTGSIT-AIAHDAGVIEPAGRAPYVLVVLTRG -IK-DSAKAHELIARVSRVVYEH- ->[subseq from] Beta-lactamase class A n=2 Tax=Brevibacillus TaxID=55080 RepID=J3BB11_9BACL --------VSELLEAAGGEWGVYLEDLQTNEKL-AINENQRFYAASVIKVPIMAAVFAEAY -AGKLALGDKLKLRQEDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMMIDLV-GA -DSIRSIMRKTGMENSSFYNKLMVVPAELEG--YNEITAADIASHLRYLATGKVISYDSCL -KMIAILKQQQH-RDRFPFLLPPKWEFANKTGSVTK-ITHDVGIFYTGPH---AISVSLLN -KGLAQKDAASVMARIGRLLYDTy ->[subseq from] BlaTEM-183_1_HQ529916 n=1 Tax=Escherichia coli TaxID=562 RepID=A0A3P5G6U6_ECOLX -------------------------------------------MMSTFKVLLC-AVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KE-QPLLHNMGI-VTRLDRWEPELNEAIPNDERDTTMLAAMATTLRKLLTGELLTSASRQ -QL-DWMEADKVAGPLL-------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus sp. oral taxon 836 str. F0141 TaxID=768724 RepID=D8FGV9_9FIRM ---KIKKHIEKIISESSGNICLSFYDLDDEEGF-SINEDKKVRSASMIKLLIMAEIMNQSK -NGKISLDTKIKVGKKDKVGGSGILKEFDCEHFSIKELMTLMIIVSDNQATNILIDLV-GM -DNINLMGKRLNLKSASLQRKMMDIK-ALEKGRDNYISAIDVKVILEKIYRKTLVDEKSSE -LMLDILLRQHE-RQRLGRFLDEEVKIASKTGDLDK-LENDGGIFFLENKN-YILVVLIDD -AV-TNAMAQETIGKISKYIYDE- ->[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0005500C1E --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPSEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGREVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQIISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus acetophenoni TaxID=614649 RepID=UPI000BE2F069 ----LIEKIRSLIECVDFKVHLFVKEAKSENYIlNEKSDDIFSSASLIKVPILLGVLDYLE -KNNQTLDEELPIAIENKVEFSVVTEQNLDS-CTLYELLVWMIITSDNSATNVLIDFI-GM -EELNIYFNKIGLTQTRLQRKMMDFKS-LNKGYDNVTTARDMAYLFSRVYQQDLLSDQYSQ -LVIDILCRQRV-HEGLKRYITDDIFIAHKTGSLDT-VCHDVGIVYHPSNN-YIIGIFLTE -LA-DVEIGKRLIGRISKIVYEYf ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M4H7_9BURK ---AMHRELERFARQEGTRFGVYVHDLASGQRM-SFHGDERWYLASSVKVPVAIAVLRAVE -RGDFSLETPLTLRAGDYVDGAGITNRQPVGALTVRWLLEQMIIYSDNTASDMLIGLVGEA -NAVTQLLVPTGLERITSLADVRRHAYAYYADGLNSGRLDAYGDLLVQLVDGLALNAQHTA -YLLGVMERVKTGPRRIKAGLPAGARFAHKTGTQR-ARTCDSGLVTVPAQERRVIVVACTR -GEPSTARSDRTLRHVGIALC--- ->[subseq from] Peptidoglycan glycosyltransferase n=1 Tax=Calothrix sp. NIES-3974 TaxID=2005462 RepID=A0A1Z4NJ73_9CYAN ----------------HLDAGFFFLDMETGNYI-DHNGEKIFPAASTIKFPILVALFQEID -AGRVKLNETLTMCRDLITGGSGNMQYRPGTRFSLLETATQMMTVSDNTATNMIIDRLGGL -NRLNQRFRSWGLQNTVMRNMLGDFGGT------NTSSAKDLVRLGALIANNQLLTASSRS -RVLDIMYRVRN-RSYLPSGLGSGARIAHKTGTLA-ALVGDTGIIQTPSGRRYLAGIFVRR -PRWD-DRGVELVRQVSQIFYG-- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10401 TaxID=2678657 RepID=UPI0013D4C43D --------------------------NETGDILfQQNSDKSIPSASIIKIPILIALMEKVE -NEAVNLDSLYTLQASDKVGGAGEMQHLPEGSLTFRYLAEEMIRISDNTATNILIRTI-GM -DYIQQWLSKHGYKATQLNRFMMDFK-AIEAGRQNYTSPKEINEILLNLWNGAWLKEASKE -EIMHWLKGCAD-NSTIPSRLPTDTIVAHKTGTLDY-VRGDAGLILG--DKPLILSVFVEN -FQ-SMEEAEAAIGKIALKAYTDf ->[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium halophilum TaxID=1416801 RepID=A0A1H7BVP7_9BACT ------------------------IQGAEGEILaEYEPDKRVPSASIIKIPILLALLEAVE -KEELSLEDRYRLRNQDKVGGAGELQFEPDGSLTYRTLATEMIRISDNTATNILIDKL-GM -ERIQGWLNERGFTATQLNRKMMDFA-AIEQGKQNYTSPAEINRILLMLLDATSVSAETAA -SARQLLTACAD-RQTLPALLPKNLEVAHKTGTLDY-VRGDAGIIFGK--RALVVSVFVEH -FQ-EIEDAEKIIAEIGRLAYEIy ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. An269 TaxID=1965613 RepID=A0A1Y4FJX4_9BACE ----LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQALAICNRFD -QDGLSLDTSLTVRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV -AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD -FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVNYALAVFIKD -FKGNESQASQVAARISAAVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8QRU5_9BACT --qKTERQLRDLLEKSPAVTGLVAIDLTSGEAF-RFNQDQVFTQASAIKIPILLEVYKQAQ -NGKFALHHLHNIAPAQVVGGTGIIKDLPDSTFSIRNLAVLMITLSDNTATNALIDLV-GL -ANINATLQSLGLKQTRVQRKMIQGAA-SGRGEENISTPAEAAQILQMLYKGQFLNKAASA -EIVSILQKTNREASRLTSGLPAHVPLAFKPGILN-GVSTEWALVLLPER-PYAVAMMENY -KVP--GQPDRTMEEVSAVLYQYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A4Y3PEX2_BREPA --------VSELLEAAGGEWGVYLEDLQTNEKL-AINENERFYAASVIKVPIMTAVFAEAY -AGKLALEDKIKLRQEDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMMIDLV-GT -DSIRNAMRKTGMENSSFYNKLMVVPAELEG--YNEITAADIGSHLRYLATGKVISYDSCL -KMIAILKQQQH-RDRFPFLLPPKWEFANKTGSVTK-ITHDVGIFYTGPH---AISVSLLN -KGLAQKDAAAVMARIGSLLYDAy ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E6J5J7_9CHLR ------SEIKSLVSEINGEVGVAALNLKNDKNI-YINEDESFFMASVFKIPLLITLYKQVD -LGNIDMDQRITLAQDLKTGGSGVLRELTPGIPTLFDLAMLMIIISDNTATDILFNML-GK -DKINSLMRQNNLSKTFTPMSCQDLLSALNEDKSNVSTAYEMVTLMKLLTTGKILSESSTN -SVLSILKSQKL-KTIIPHYIPKNIKIANKTGGVYS-VRSDVGTVWSPKG-PYTIAIMAKN -VT-NEPDIDTKLAKISLSIYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Margulisbacteria bacterium GWE2_39_32 TaxID=1817872 RepID=A0A1F6QC09_9BACT ----------------GGIVGVSIKDLTTGEYF-SINGDVQFNPASVIKVPVMVEAFHQMA -LGRISMDEKLFLHQQNKIQGSGSIQYLPNGSFTVKRLINLMITDSDNTATNMLICRL-GT -KNINQYMRKVGLRHTVLKDPTM--FCKLPG-KYNLTSPNDMLMLLEKMYKGELVSADASK -QMLDIMKAQLH-KWGIQRFLPASAIVANKTGSLDF-VRNDIGIILDKKH-PYILSIFSKQ -LP-SNYYGSVLVGSISKVIFD-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A4U2MI98_9BACI --qTIEHDILALVETFNGRIAYKIEN-GLGDTI-GYHETESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE -RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=UPI0012B3528D ---------------AAGPAQVYFTNLSTNQSL--YRGSETMTAASMIKVFILAKAYEDIQ -NGSLSRNETFTLTSDNVVGGAGVLQGRGYGSVSLQEALELMITESDNTAANLLIDRL-GM -DRINAYMQRHGYTHSVLRRKMMDTE-AMAAGRENLTSTRDIALLFKRLYQGKCVSPAQDR -EMLAIYKRQTD-NDSIPGDLPRGTVVAHKTGEVND-LRHDGGIVYTPNGD-YVLVIFTRN -YTP-YETMADLSEKIYQAV---- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Margulisbacteria bacterium TaxID=2053573 RepID=A0A2W4IF55_9BACT ----------------GGIVGVSIKDLTTGEYF-SINGDVQFNPASVIKVPVMVEAFHQMA -LGRISMDEKLFLHQQNKIQGSGSIQYLPNGSFTVKRLINLMITDSDNTATNMLICRL-GT -KNINQYMRKVGLRHTVLKDPTM--FCKLPG-KYNLTSPNDMLMLLEKMYKGELVSADASK -QMLDIMKAQLH-KWGIQRFLPASAIVANKTGSLDF-VRNDIGIILDKKH-PYILSIFSKQ -LP-SNYYGSVLVGSISKVIFD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3R9AGW2_9BURK ----------------------FALDAGSGRSL-GWREDERFGMCSTFKLLLAATVLDAAR -QGRLDGTAPIHFSDDDLVPHSPVLREHLALGLTAPELARATQLTSDNAAANLLIRKLGGP -EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE -RLREWMVETGTGLARL-------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Bernardetia litoralis (strain ATCC 23117 / DSM 6794 / NBRC 15988 / NCIMB 1366 / Sio-4) TaxID=880071 RepID=I4APP3_BERLS ------------------------------------------------------------- -----------------------------------------------------------GV -EKTNKFIKKLGLKHTIIAASEEKMHESFDNQYLNTTTPLDAVSLLKHFYQGKILKKETQD -FLWKLLVETRTGSNKIKAGLPDKIILGHKTGSSFRKAENDIGIVITEKN-TYAVAIFIKN -STESNEVNNTLIAELSKMIFEY- ->[subseq from] ClassA n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T154_9BACT ---KLAERIDSIIGDKKMTVGVAAEYADMHFV---LNDSVRFPLLSVFKTHVAMAVTARMQ -MDGISPDSVVHIDKGRLKKYSPLRQKHPDSDITIAELMRYSVAESDNNACDILIDLAGGI -DYVDMYIRSLGVSGFSISETEASMHANRQLCYANWSYPESMLDVLKVVFAP---GDTRFA -LLRGIMLGTSTGRDKIPAGVPEGIAVAHKTGSSDKAADNDAGVVMLPGGN-CYIVVFIMD -SAETDSTNAATIAAITRAVLA-- ->[subseq from] Uncharacterized protein n=4 Tax=Fusobacterium TaxID=848 RepID=A0A0M1VWP4_FUSNV --tEWKKKIEKIISQVEGNVCINFYDLNKNNGF-SVNGDKKVLSASMIKLLILAELMKKIF -ENKFSLSDTVMMANFMKIGGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Fusobacterium hwasookii TaxID=1583098 RepID=UPI0004975C39 --tEWKKEIEKIISQVDGKVCVNFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKIS -EDKFSLSDTIMMANFMKTEGDGVLKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLRETFLERRMMDAEA-RKNGYDNYTSADDISLLLKLIYQEKLINKEASQ -LMLEILLKQQQ-GERLQRYLPTDIKIAHKCADLDN-LENDGGIIWLEEK-VYILVVLTSR -MS--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium ISCAR-4553 TaxID=2558931 RepID=UPI00142232FC --------LDEIVARQEAVVAVSVRDAATGTRL-DRLPDRPFHAASTMKVPVMIEVYRQAA -LGRFRLSDSLTVRNASIVDGSPYRYERLGTRMALRDLVDRMITVSSNLATNLLIDVV-SA -DSVQATVERLGGHGMRVLRGVEDLA-AYRQGLNNVTTAPALAALLEALAAGRAVSPEADR -EMIGILLEQRF-NEMIPAGLPAGTRVAHKTGWIT-GIHHDAAIVYPAGDAPYVLVILIEG -IE-DPHVAATLGADIARAVH--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A327J5A8_9BACT ----LQQELVSLTEMYTVKPAIYVWDYETGNYI-DINADKSYSTASIIKIPVLIDVFKSIE -AGQLSLEDKIPLTEYYRSEGSGSLQFKARDSYTIDELAERMITESDNSATNMLMAKVGSM -TDVNQSIRDWGLKNTSVHTWLPDLTGT------NRTTAKEMAEMLYNIDEDKFLSEESRS -KMLNYMGHVHN-NRLIQAGLGAGSVFLHKTGDIGT-MLGDAGIVITPNGKKYIVVILANR -PH-NAIAGKDFIVHASEIIYNY- ->[subseq from] Beta-lactamase n=1 Tax=Cystobacter fuscus DSM 2262 TaxID=1242864 RepID=S9QP24_9DELT -----RESLQERISQVGASVAVAYQRLGGSPDAlYLEADRSFHAASTMKVPVMLEVFRQVD -AGTLSLEEPVTLTRESIVDGSPYVHERLGQSVPLRELVERMITRSSNLATNLVLSRV-DA -RRVTKTLRALGARRMTVLRGVEDGK-AYAQGLNNTATARDLASLLSALERGRAASPASTR -AMRSILLAQEL-NREIPAGLPPGTPVAHKTGQIS-GILHDAAIVYPPGQPAYVLVVLTRG -IP-DEAVARSLIVELSRQVYAH- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000E39A6F1 -----LARLAKVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -ERVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGARRIKAGLPSGTVLAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus lacrimalis 315-B TaxID=596330 RepID=D1VS05_9FIRM ---KIKKHIEKIISESSGNICLSFYDLDDEEGF-FINEDKKVRSASMIKLLIMAEIMNQSK -NGKISLDTKIKVGKKDKVGGSGILKEFDCEHFSIKELMTLMIIVSDNQATNILIDLV-GM -DNINLMGKRLNLKSASLQRKMMDIK-ALEKGRDNYISAKDVKVILEKIYRKTLVDEKSSE -LMLDILLRQHE-RQRLGRFLDEEVKIASKTGDLDK-LENDGGIFFLENKN-YILVVLIDD -AV-TNAMAQETIGKISKYIYDE- ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus boronitolerans JCM 21713 = 10a = NBRC 103108 TaxID=1294264 RepID=A0A0A3IDZ5_9BACI -----EQRITTLIQESPYNVHLFIKNLTTNQLLiGHQLEASFSSASLIKVPILLALLSHIE -KNKLSLDSTLTISPADWVDFSVISEQRLTQ-STFYELLVWMIMTSDNTATNVLIDVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVEQ-LAKGIDNRTSARDMAHLYTQIYQQKLLSASYNK -LVIDILSRQRV-YDSLKRYLVDDVRLAHKTGGLDT-VDHDVGIFYTHAVD-YSMGFFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Serine hydrolase n=1 Tax=Cyclobacterium qasimii TaxID=1350429 RepID=A0A512C9G4_9BACT ----------------------YIIQDKDGKVLsKLNADKQIPSASIIKIPLLLYLMEKVE -QGELALHETYKLKNSDKVGGSGELQFKPDGHITYELLASEMIRISDNTATNVLIRKV-GL -RSFQEWLHTNGYKTTQLNRYMMDFD-AIAKGQQNYTSSAEMNRLLLSLLNEKSLNKASTL -QVIEWLKNCED-NSALPYLLPEVVAIAHKTGTLEY-VRGDAGIIFG--KRPIVLTVFVAH -YS-NLENANKIIAEIARLAFLD- ->[subseq from] Uncharacterized protein n=1 Tax=Tumebacillus algifaecis TaxID=1214604 RepID=A0A223CZI5_9BACL ---ALAPDLQRLIEAGRGTYGVSIYHLESQSEF-SYQQDESFYAASIIKVPIMAAVFDQAS -KGNLSFSEKITLRAEDKVTGSGLLQNLSPGLLSIYDYTVLMIIDSDNTATNILIDRI-GT -QAIQAAMQEWGLEGSGFYNKISVIPAKIEN--FNQITPRDMTHLLKQIADGKVVSWRACA -EMVQIMKQQKY-NEGLPSLLPKQWECAHKTGWIN-GTDHDMGLLYFPRN-TFAVSVFGKN -IT-DRKDAHSLMGQIGQLLYE-- ->[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium qasimii M12-11B TaxID=641524 RepID=S7WE28_9BACT ---------------------SYIIQDKDGKVLsKLNADKQIPSASIIKIPLLLYLMEKVE -QGELALHETYKLKNSDKVGGSGELQFKPDGHITYELLASEMIRISDNTATNVLIRKV-GL -RSFQEWLHTNGYKTTQLNRYMMDFD-AIAKGQQNYTSSAEMNRLLLSLLNEKSLNKASTL -QVIEWLKNCED-NSALPYLLPEVVAIAHKTGTLEY-VRGDAGIIFG--KRPIVLTVFVAH -YS-NLENANKIIAEIARLAFLD- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YB64_9BACT --kKLESRVEGTASRLDGVMGVAILDLTDGRIL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKARLDGIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFMVAVSDNAAANVLYDRV-GR -DNVNAMLHSLGLSKMMLRRKMMDIAAARRG-DENVATPREMVRLLEAIYKEKALNKQATA -EFITQLSTLKQ--SYIPRSLPDNVQVANKPGELD-AVRNDSGIVYALNR-PFAISVMTAY -DR-DEKAAERAISEVALEAYHYf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G4G2_9BACT -------------------------------------------MASVYKLPIALELLAQVS -QGALTLDRQVPILASDIRACCTLSRRHPNGGLSAGELLELMIVESDNTAADAVLKLVGGP -PVVERRLRALGFDAINVNRYEGDIAFRYTRDPRDTATPDDMARFLARLQLGNLLPRAPTD -LLLDLMARAKTGPHRIKALLPPDTSVAHKTGTTDV-VINDVGIVTLPTGGHLVLAAFAMN -GG-RVTAMQKTIAQLAGAAFECf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A426H0P4_9BACI --qTIEHDILALVESFNGKIAYKIED-GLGETI-GYHVNESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTSTNMMMSLL-GI -DEINRCIKELGLKNTILERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -RIMRVFDNQQI-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQA-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus cavernae TaxID=1674310 RepID=A0A3S0TYA1_9BACI ---ALNDSIKQLLEPFDGRIAFKIEM--DDQMI-EQKSEDIFPSASLIKIPILIETFRQSE -ERQIYLNQPVTIPLQERVGGSGVIHAMSDKVMTIEDILTLMIVVSDNTATNLLISLL-GQ -DQINGCLKELGMDKTVLNRKMMDSK-AIEEGRDNYTTAADVLASLKAINEGTLLTAESKQ -RILTIMKKQQF-TDKLPARMDEKVSVANKTGSLP-GVTHDCAIITYGEKT-AYAAVLTDG -LS-SEEEGRQMIAKIGELVYEY- ->[subseq from] serine hydrolase n=1 Tax=Senegalimassilia anaerobia TaxID=1473216 RepID=UPI0013896BEF ----LRDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ -SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNVATNLIIDAV-GM -PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSPDMSE -FALDLLKGQHD-DAGLLEGLPVGSVFAHKTGTLD-GVFNDGGIVLD--QNPYVMVVLSSD -AERSQ--AQACMVDIAQAA---- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sp. YIM 98839 TaxID=2663380 RepID=UPI0013DCAC76 --nQLKVDIQAIIEDSGGEWGIAIEDLHTNEIF-TEQADRPFYAASIIKIPIMITVFKRYE -DGAFTLSDKLSLKREDMVGGSGVLQHMTPGTLTIYDLLMLMIIQSDNTATNMLIDLV-GT -KEIQQTLDTIGAFNSKFYNKLMIVPVQ--KEGSNIITANDMTLLLKQLVNGQIISVHACQ -QMINIMKKQQI-RESLPGKLPKKWELAHKTGNVTK-VRHDVGIFYVGNRT-LIASVLSQG -MN--DLVSKELFHDIGLAIFN-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A270AFY5_9BACI ---TIEHDILALVEAFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPSGEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI000BA4EF6F ---TIEHDILALVEAFNGRIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPSGEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESRE -KILHVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Senegalimassilia anaerobia TaxID=1473216 RepID=UPI0009DA0AC2 ----LRDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ -SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNVATNLIIDAV-GM -PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSPDMSE -FALDLLKGQHD-DAGLLEGLPVGSVFAHKTGTLD-GVFNDGGIVLD--QNPYVMVVLSSD -AERSQ--AQACMVDIAQAA---- ->[subseq from] serine hydrolase n=1 Tax=Leptolyngbyaceae cyanobacterium CCMR0082 TaxID=2304604 RepID=UPI0013D2ABD0 ----LKTKLEELQELIELTPTIYVFDLDTGNYV-EVAGNAETPAASTIKLPILIAFFKAVD -EGRITVDQALAMQSNQIAGGSGDMQGQPPGTYTALEVATQMIINSDNTATNMMIDLLGGP -QALNQQFADWGLTMTILRNPLPDIEGT------NTTSAQDLVRMIAHLHKGDILSLRSRD -RVMNILQRTYN-KKLLPAGVSETTISYNKTGNIGE-VLGDVALMDLANGKRYAIAALVRR -PEND-GRAQELIRRISQAVYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A1N6W851_9BACI --qTIEHDILALIESFKGKIAYKIEN-GHGDMI-GYRENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKQLGLKNTILERKMQDFK-ALKEGLDNTISAEDTITCLKAIHTGNFLTKESQE -KILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTEG -MK-SEEESRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. B4EP4a TaxID=2590665 RepID=UPI001154CEA9 ---TIEHVILALIETFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLTKESQE -RILRVFDNQQL-RDKLPSLMGKGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BHU9_BREBE ----LFAQISSLIKDAGGEWGIFFEDLQTGETL-SINEVQRFYAASAIKVPIMTAVFAEAY -AGKFALEDKIKLRAEDLVGGAGVLQHMTPGTFTIRDLVTLMIIQSDNTATNIMIDLV-GT -ESIRNAMQKTEMTNSHFYNKLMVIPAELEG--YNEVTAKDMGSHLRYLATGKVISYDSCL -KMVAILKTQQH-RDRIPFLLPPKWEFANKTGSVTK-ITHDVGILYIGSHA-VTLSILNKG -LE--QKDAADVMAQIGNLVYHVy ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A413HDX0_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537J774_9BACT --qNLKQQIIEQLSQPKGTFAVAFKDISSKKEL-IINEKEIFHAASTMKTPVMIEVFRQAS -KKKFSLNDSLVLKNESIVDSSSFAYKHLGEKRSIYDLVYQMIVVSSNLATNLIIEKV-DA -SNVTQTMRRYGANDIQVLRGVEDQK-AYDKGLNNTTTAYDLMLIFEKIARGKAVNKKACE -AMIDILLDQKF-NTIIPAQLPKDVKVAHKTGFIT-GIHHDSGIVFLPDGRKYVLVLLSKN -VE-DEDKAVKTMANVSGMIYQY- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A354PGU9_9PLAN ---RLAELIQPLIDAHDGKIGLAIKHLGNGNGF-VYRADDPMPTASLIKMAVMVTAYDQIH -AGTLSRTLPIALKEQDKVPGSGILTAHFSEGLSLRDAIRLMMAYSDNTATNLVVDQI-SL -PATATLMKSLNLPNTQLHSKVYRRDTSIDLERSGSTTAAETIAMLEWIDRGQIINREICD -EMLEHLYANQD-SSKLARSLPAKVRVAHKSGDVN-ASRCDAGLVDGPQGR-IAICVLTDE -NASDNNAALKLMGEIAAVTYRHy ->[subseq from] Beta-lactamase n=1 Tax=Bacillus asahii TaxID=228899 RepID=A0A3T0KP35_9BACI --qSIEPKILELIETFDGRIAYKIEN-DRGESI-SYHEHEAFQSASLIKIPMIIEGYRQAE -NQDIYLNQPLTIPRNEVTRGSGVLHTLSDKVLTVEDLLTLMITISDNTSTNMMMTLL-TF -EKINQCIQELGLENTVLERRMFDFKA-LKEGRDNTMSAADTVLCLKAIHTGNFLTKASQE -RILDIFEQQQF-KERLPAMMGKGVKVGNKTGSLR-GVMHDAAIIRSETET--VYASVLTE -DMASEEESRQIISKIGKLIYDE- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. vincentii TaxID=155615 RepID=A0A2G7H8V4_FUSNV --tEWKKEIEKIISQVEGSVCINFYDLNKNNVF-SINGDKKVLSASMIKLLILAELMKKNS -ENKFSLSDTVMMANFMKIGGDGVLKELNTGHFTLKELATLMIIISDNQATNILIDFL-GM -ENINQLGKELDLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LILDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGDRA-YILVVLTNG -MP--NLQCKQTIGKISKFIYDK- ->[subseq from] Beta-lactamase n=1 Tax=Fibrobacter intestinalis TaxID=28122 RepID=A0A1T4NA50_9BACT --qSLTDTLSKIASEYPGEIGVAAI-INNSDTI-AVHDKPVYPMMSVFKVHQALALCNVFD -RQNFSLDSSITIQREELDPWSPMLKEHPEPELTVKNLLRYTLTQSDNNASNLLFQKFVDV -SQTDSFIASIPRASFQIAFTEKEMSANHDKAYANYTSPLGAAMLMNRLFNDSLVSREKQN -FITNTLQECTTGKDRIVAPLKEGVVIAHKTGSGYTNAHNDIAYIQLPNDIHYSLAVFVKD -IQGNETLAAEAISRLSASVYAY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0A368_9BACT --tKLQEKIAAVDRNLDGVMGVAVRDLTNSETY-LLHGDDVFPQASSIKIAVLAELYDQEQ -RGRARLADLYTVRSEDLVPDSFIMGGLTPGVITNRDLATMMVAVSDNSATNVLIDHL-GM -PNVERMLASIGLKNTHLQRKMMDIAAA-RQGRENVSTPREMMTLFDAIYRNKLFDKELTA -DFFKVLSTPK--DSSIPKLLPADLNIANKPGELE-AVRNDSGIIFVPNR-PFILCVMTTY -LH-DERVGQRSISEIALAAYEYf ->[subseq from] serine hydrolase n=1 Tax=Chitinophagaceae bacterium PMP191F TaxID=1691979 RepID=UPI0006BC04FD ----IQEEITNLLQQQQGIFAVAFKDLSSGKTI-LINEHEVFHAASTMKTPVMIEVYKQAA -EGKFSMDDSLELKNSSIVDGSTYQYGQLGKKSTIAALVYDMIIVSSNLATNMLIEKT-GA -PNVMQTMRQLGANDIQVLRGVEDTK-AYEQGLNNTTTAYDLMIIFEKMAKEEIVNKQASK -QMINILLNQQF-NDIIPAMLPKNVSVAHKTGNIT-GVQHDSGIVLLPDGRKYVLVLLSKQ -LT-DTAAAIKVMANISAILYR-- ->[subseq from] Beta-lactamase n=2 Tax=Sphingomonadales TaxID=204457 RepID=A0A2E0Q6C5_9SPHN ----FERQLASLADGSAGRIGVYAIDLNTGEEV-GVLEDQRFPMASTSKVAIAATFLAGVD -QGRWSLSSEFELPG-------------RGTYISAGEHLNLMITRSCNDCTDALLNAVGGP -QAVNKWMRQAGIYDFELTRNIASLVRASQIAFEDSATPRAMGKLLAGIYQGQWLTPYSRR -VLLEAMGGTVTGKRRMSSALPMSANLAHKTGTLSR-TASDIGIFQTPDGHMVAAAIYVTG -QSVSMEVEN-------------- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. PCC 7003 TaxID=374981 RepID=A0A1B1TT58_9SYNE ------TTQAAIAADPNLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFLEAVD -SGKVQLDDSLTLTKEVIGGGSGSMQYTPGSTYTALYTAREMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00105D43B0 -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -ERVNAVTRELVPEGFGPITTLTDVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Bryobacterales bacterium KBS 96 TaxID=639034 RepID=UPI000372583E --qKLEHGVETLDSGLDGVMGVAILDLTTGREW-MYHANEVFPTASTIKLAVLTELYHQQE -TGAAKLTDMYTVRKEDLAPDSAILDNLTPGVLTNRDLAAAVVAVSDNSASNILTNRL-GM -ARINTMLDGLNLKQTRMRRLMMDLEAA-KQGRENVATPHELVLLLQAIYQNKLFRPELTQ -DLLNLLSTPKS--SSIPRLLPEDLKIANKPGELF-GVRCDAGIVFVPKH-PFAIAIMTTY -DR-DGRAAEQTISQVALLAWRLf ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=uncultured Eubacterium sp. TaxID=165185 RepID=A0A1C5RMA9_9FIRM ------EKLIAYLQREGVSGAFAVKDLRSGEIC-SFNEDEVVASASLIKMFILIRAFQKIR -AGEMTLDDQIEVRAEDVVDFSVLLFLDP-RKYSLRELLKLMIVYSDNTATNVLIDLF-GM -DGINSTIRELGYSDSVLQRKMMDFRAA-EEGRQNFTSVKEMLDLMERLYEDRLLGSPYDG -QMLDIMKGQAD-ETMMRQELPDELVIARKSGELD-ALDHDIAIVYTEKGN--YIYIFFAW -DAKDNNHARKILSETSKLVFDDf ->[subseq from] Uncharacterized protein n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A3A0D121_9BACT -heKTEAKLWEIAGNVSGVMGIAALDLTSGERF-GVNENMVFPQGSAIKIPVLMEVYKQAT -EGKFRLTDLRWIDKQHKVGGSGILQQLGDHTLSIRDLAILMIVLSDNTATNMLIDLV-GM -ENVNRTMSSLGLTQTRLQRRMINAAAS-GKGEENLSTPSEAVRIMEVLHRGEFLNRQVCD -EILEILKKPKSG--GLNAGLPANLPVAFKPGGIP-GVSTEWAIVYLKER-PYAVAVMENY -EM--NGEAKSAMKEISRILYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium GWF2_32_7 TaxID=1801605 RepID=A0A1F6PM50_9BACT ---RLTNRLKYLAKQYSLEPGIFIWDFSTGQYV-DINADQEFPTASIVKIPILLQLFRRAE -LGFANLNDRMSLAEYNITGGSGYLQYKPVGTFPIHHLARLMXXXSDNTATNMILSTVGGT -NELNRVLRSWGFSKTHMSDLLPDLYGT------NVSTPKDMGTMLFNLDNSDFLTLKSRA -AIVDIMSHVRN-RFLIQAGLPDNAQFIHKSGDIGT-MLGDAGIVMLPDGRKYIIVIMVKR -PW-NLYSAKEFIINASKITYNSy ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter ruber TaxID=990371 RepID=A0A1G9LU15_9SPHI ----LKKKINAEFAKNKGIFAMAFKNLSTGEEI-LINEKIHFHAASTMKTPVLIEAYKQAA -AGKFSIEDPLTIKNESIVDGSPFSYTKTGTQVKIYDLLYLMIIKSSNLATNLIIDLV-GA -KNANNTMREMGANDIQVLRGVEDTKA-FRKGLNNTTTAYDQMLIFSEMADGKIVNQESSD -AMINILLDQKF-NDKIPAKLPKDVKVAHKTGWIT-GVNHDAGIVFLPDGRKYVLVFLSKE -LT-DDQAAVKSMAKVSRMIFNYf ->[subseq from] Class A beta-lactamase n=1 Tax=Barnesiella sp. WM24 TaxID=2558278 RepID=A0A4Y9J114_9BACT --sQIEERLKTYVAAQDTRIGVAVI-IDGKDTI-SVNGNRDFPMLSVYKFPQALAVADYCM -KKGITLSDTIGIQAKEIKEWSPMRNKYGVSDLPLSEILEYSLQQSDNNACDVLFRLIGGS -QVSDSLMKASGYGDITIGSTEDEMHRDPYLCYQNRATPIAMARLFDKFYRLEMHDSPVHE -AVGAMMMLCGTGDNRLPAPLATDAVIAHKTGTGGRNGINDAGYVFLPNGRGYAIAVFIAD -SAYDMARTEKIIADISKIVYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A1Z3CIR3_FUSNP --tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS -EDKFSLSDTIMMANFMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Ammoniphilus sp. YIM 78166 TaxID=1644106 RepID=UPI00106F0B9B ---QLVDQVKQQIESAGGEWGVVLEDLQTGEEY-RWNAEERFYAASVIKLHIMVAVFGAAN -EGKFNLSDTLVLRREDITTGAGVLQHMTPGTLSIYDVITLMIIQSDNTATNMLIDLV-GK -KRIRDVIKELELNNTTFYNKLQVVP--YPLKGSNQTTAGDTALLLKRLVTQKVISWHACE -QMIDIMKKQQL-NDFLPSNYPKSWEFAHKTGMVTR-IHHDAGVLYRNGRA-LLVSFFSRG -LE--TKEAREAMSHIGQAIYEY- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI001104F167 --nSVQQQLEALEKSSGGRFGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDRTEPT------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. An51A TaxID=1965640 RepID=A0A1Y3XGV6_9BACE ----LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQALAICNRFD -QDGLSLDTSLTVRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV -AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD -FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVNYALAVFIKD -FKGNESQASQVAARISAAVY--- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Pseudomonas TaxID=2583993 RepID=A0A350N2V5_PSESP -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -ERVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A165NVG8_PSEST -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Rufibacter sp. DG31D TaxID=1379910 RepID=A0A0H4VU76_9BACT --nSLKEQITTELSKQKGTFAVAFKDLKTGEEL-LINEHTSFHAASTMKTPVLLEAYKQAA -EGKFSITDSILVKNESIVDGSLYSHRLLGQKRTLYDLLYRMIIQSSNLATNIVIEKL-DA -KNVTQTMRSLGMKDMQVLRGVEDTK-AYRQGLNNTATAYDLMVLFQHIAQGKAVSKKASQ -EMVKILLDQKF-KDIIPSKLPTDVKVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKE -LQ-DEPAGIAAMATVSEMIYKH- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7MCA2_9BACT ---SLRARIEARIAQAPARVGLYYRDLSGGDSL-TVGAAARFHAASTMKIPVMIQLFRDQD -AGLLSLDDSVTVTNTSIVDSSPYQYKRLGQRASIRELIELMETVSSNLATNLLITRV-DA -KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIANGKAASAASCR -AMLAILGRQHF-TEGIPAGLPPGTRVYHKTGWIGQVVYHDAAVVEPTDGRRYVLVVLTGG -IQKD-EDSHALVRDLSRLVFD-- ->[subseq from] Serine hydrolase n=1 Tax=Pleurocapsa sp. CCALA 161 TaxID=2107688 RepID=A0A2T1CIH1_9CYAN ----LKSQLEQLATQYDIKPELLFIDLDNKGFV-SIDSKLPLPAASTIKLPILVAFFQDVD -RGKINLAEEFIMTKDVIAGGSGGMQYEPPNSFSALKTAEQMMTNSDNTATNMLIKRLGGM -EQLNQRFTKMGLTATKLHNPLPDLTGT------NTTSSADLGNLLVKIDGGSLISLRSRD -RMLYIMRNIVR-NTLLPEGLEPGALIAHKTGDIKS-VLGDVGIIDMPNGKRYIASILVKR -PDN-SPLAKEFIQKASGVAYQYf ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sp. SYSU K30005 TaxID=2666135 RepID=UPI0012D97B5B -----EQMIQEMIKETPYNAHLFVKNLKTNQLLiDYQLESSFSSASVIKVPILLALLTYME -NNNISLDSTRSISPDDWVDFSVISELRLTQ-STLYELLVWMIITSDNTATNVCIDVV-GM -EFLNDYFRQIGLQDTVLQRKMMDVER-LAKGIDNRTSARDMAHLFTRIYQQDVLSPSYSK -LVIDILSRQRV-HDSLMRYLVDDVKLAHKTGGLDT-VDHDVGIVYSSAID-YSIGVFLTN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides ovatus SD CMC 3f TaxID=702443 RepID=D4W9A8_BACOV ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus acetophenoni TaxID=614649 RepID=A0A285U3R2_9BACI ------EKIRSLIECVDFKVHLFVKEAKSENYIlNEKSDDIFSSASLIKVPILLGVLDYLE -KNNQTLDEELPIAIENKVEFSVVTEQNLDS-CTLYELLVWMIITSDNSATNVLIDFI-GM -EELNIYFNKIGLTQTRLQRKMMDFKS-LNKGYDNVTTARDMAYLFSRVYQQDLLSDQYSQ -LVIDILCRQRV-HEGLKRYITDDIFIAHKTGSLDT-VCHDVGIVYHPSNN-YIIGIFLTE -LA-DVEIGKRLIGRISKIVYEYf ->[subseq from] serine hydrolase n=1 Tax=Emticicia oligotrophica TaxID=312279 RepID=UPI00025F5AAF -----------------MNVSMVVEEMNGNKIY-EYRPSVKMPSASVIKIPILMTLMGKVA -KKELSLEDTHTLLHEEKTGGSGVLAEMSDGKFTIRELAQEMIRSSDNTATNILINKV-GR -ESVNAYLQQWGMSQTRLNRVMMDTEA-VKQGRENYINAREVNALLQMIYGHKIATPALCD -EMLEMLKNCAD-KSTIPSQLPQNLSIAHKTGTLAY-VRGDAAIVFTQN--PFVISIFVEG -FDK-ESTAEKVIGDLAKICWN-- ->[subseq from] Beta-lactamase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537K9E4_9BACT -------------------MGVYVRAVATGEEV-ELNADRPFQMASVFKIPILAELLSETH -AGRRPLDNRIILTDQMKAPGSGVLKELSAGTLTVRDLATLMIIVSDNTATDILLGLV-TK -EAVNSRLRACGLERTTVAMSCRELLWVYRDERANTTTPREMAVLLGHVLRPTLLAPDVCR -QMLDILRRQQI-RDRLPLLLAPAVDIAHKTGSVSR-VSNDAGILYAPKS-PCVVTVFTRD -LAD-DLKGRMAIAQVGQAVYEAy ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. V59.32b TaxID=1758642 RepID=A0A3E2J5H1_9BACI ---ALEESIMQLKNHADGRIGLHIEI--DGKVI-ESDGQEIFQSASLIKIPILIEAFRQSE -EKRIYLNQPVTIPMTERVGGSGVIYALTDKVMTIGDIITLMIIVSDNTATNLLISFL-GQ -DEINRCIKDLGLDKTVLNRRMMDFE-AINQGRDNLTTATDMLVCLKAIKEETFLSSKSNE -QILSIMRKQQM-TDKLPALMPEKVSVANKTGSLP-GIVHDCAIITYGEKT-AYVAVLTSV -SS--EEEGRQVLAKIGKLVYEY- ->[subseq from] serine hydrolase n=1 Tax=Luteimonas abyssi TaxID=1247514 RepID=UPI000737D495 ----LRERLEAADRRFAGDIGVFVQHLGSGEAF-SFHADEPWYLASGIKVVVAIAVLQRVE -AGDLSLETRVRLRETDFVDGAGQTNSWPAGTLRVSYLLEQMIVYSDNTATDVLIRTV-GE -DEVNVLARALGLTITTLADVR----RAYYATNVNAASLRDYARMLEALAEGRALGTEQTR -YLLDVMTRVRTGDRRIKAALPAGARFAHKTGTQYR-RVCDLGIVTVRGANEQVVVAACAR -GA-PTAAGERALRDVGAAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium ljungdahlii TaxID=1538 RepID=A0A162L2T3_9CLOT -------KILAAIDLKKLNCSFVIENLKTGEKI-AYNENMVVPSASLIKIPIMMEILNQVK -EGKLSLKQRITVEDNVKVPFSILNLLETGNSYTLKDVITLMIIQSDNTAANILMDLA-GM -DNVNNYIKNLKIKNTVLQRKMMDSKAR-KEGRENKTTAADMAKFFEIIYKGEKAEESYSI -LMKDILTNQLD-NSVMRLSIPDDTVIAHKTGDLY-GISHDAGIVYLPNVD-YIFCGLTWD -AV-TNNFARETIGKISKIAYDYf ->[subseq from] Beta-lactamase n=2 Tax=Rubrobacter xylanophilus TaxID=49319 RepID=Q1AVA6_RUBXD ------EEAAGVVREHPGVAGFYVRDLKSGAGY-GVRPDQVFFSASTIKVPVMIAVYRRID -QGRLHYSDRIVTTEEDWAAGAGWLRWQTPGASTVEDALWLMIAQSDNVATNALVRLVGGP -GYVNEVARSLGAEDTALHWKLSSERAAVP-SLDNRTTPRDMALLLAKIRSGEAASRYACR -EMLGLLEQNNL-EWWIEGGVPPGVKVANKGGWLDS-TYNDAGIVEYEER-PYVLAVFTEY -GP-GLGEGGRYLQRISRAVW--- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. CFH S0501 TaxID=1644114 RepID=UPI00106E2C9E ---TLHDSIMSLVEKAGGKWGFVIEDLQTNERL-AYQEDERFYAASLIKVPIMTAVFAEQY -AGKLSFEDKVRLKKEDLVGGSGVLEQLTPGTFTIYDLVMLMIIQSDNTATNMLIDLV-GK -KSIRSIMKKTGMSNSQFHNKLMVIPAELEG--YNEVTAADMANHFRLMATGKILSYNSCL -QMIRILKQQQI-QQSLPLHLPPRWEMAHKTGSVST-NDHDVGILYVGQKA-ILISTLSAN -VPA--NLARDTMGRICELVYQLy ->[subseq from] Uncharacterized protein n=1 Tax=Synergistetes bacterium HGW-Synergistetes-2 TaxID=2013843 RepID=A0A2N1QPP8_9BACT ------QKIYELLGGLEGKAALYVEDLASGEIF-TICADEVHVACSLVKVPILALLLKDAE -EGGARLEEKISIPPEKRVGGTGLICHEPEAELSWRDVMKLMVIVSDNSATNAVIDLL-GI -DRINAFFKSIGLTSTELQRKMMDME-AIKAGRNNYTTAADMGRLLKLAATGSLVSRNVSD -AVIDTMSRQLY-TSKLPALLPASVTVANKTGDLPK-TEHDVGLFILPGGKRYVVAMLTSQ -LA-SEKEGIACIAKVSKIIYDA- ->[subseq from] Beta-lactamase n=2 Tax=Lunatimonas lonarensis TaxID=1232681 RepID=R7ZPI9_9BACT --------------------------IQEREVLsVHDPARRIPSASIIKVPILIALMQDVQ -EGKRSLSEEIVLHESDMVAGAGELQFRAPGTYSLEFLAREMIRISDNTATNLLIQTL-GM -DRIQGWLQSHGFRQTQLNRLMMDFG-AIEAGRQNYTSAEEMVRMLLELADGKYLDAKGTD -FVLELLRDCAD-REAIPSKLPAGTVVAHKTGTLDY-VRGDAGLVWG--EKPLAICVFVEG -FS-SLEQADEIIGQIALLAFDTy ->[subseq from] Uncharacterized protein n=1 Tax=Acidimicrobiaceae bacterium TaxID=2024894 RepID=A0A2E5P4B3_9ACTN ------KDLTSFAKTFTGVLGVSAVHLETGEQV-AYNSDHPLLTASTFKSILLVSLLEMVD -VQKLSLDDRITFTATKRVAGSGVLKLMRSDTVSIGDLAVLMITISDNTASQMLFDVV-GH -DRIQHTIDRLGLTRTRIPLSPKEMLLRAYSSEGNISTPADMCRLFRRIHNNEVLSCESKR -TFLDIHKGQQL-RTVIPHRLPAGTVCAHKTGQFEL-VSCDVGIVYSRHG-PYAIALMANG -ARGDRIEVNAALAALSRRVFDEf ->[subseq from] Beta-lactamase n=1 Tax=Lysinibacillus odysseyi 34hs-1 = NBRC 100172 TaxID=1220589 RepID=A0A0A3INB9_9BACI ------RMIEQLLQTCPYKVHLFVKDAKAKGYFhSLLIDEVFSSASLIKVPILIAVLDHVE -RHERSLDEVIQIQSENRVDFSVITEQQLNE-STLYELLVWMIITSDNTATNVLIDYL-GM -DALNTYFGKIGLTHTTLQRKMMDFVR-LESGFDNVTTARDMAHLFTRIYRQDLLSVPFST -LAIDILSRQRV-HESLTRYLVEDIHIAHKTGGLDS-VDHDVGIVFNHVN-DYIIGVFVTE -VTN-NDEARQFIGRLSKAVYEQ- ->[subseq from] Beta-lactamase n=2 Tax=Prevotella TaxID=838 RepID=A0A3R6AR46_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Larkinella sp. BK230 TaxID=2512173 RepID=A0A4R8CZB3_9BACT ----LRQQIEQELGKQPGTFAVAFRDLQTGQEL-LIREHENFHAASTMKTPVMIEVYKQAA -QGRFSLSDPILVKNSSIVDGSLYSYTKVGTKRPLSDLVYDMIIVSSNLATNLVIELV-DA -RKVTQTMRDFGARDIQVRRGVEDKK-AFEQGLNNTTTAYDLMVIFDKIATGKAVSPEASK -AMIRILLDQRF-NTVIPAQLPTDVQVAHKTGSIA-GVHHDSGIVMLPDGRKYVLVLLGKD -LK-DDAAAIKSMATVSRLIYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFOXYA2_FULL_40_6 TaxID=1797958 RepID=A0A1F9X070_9BACT --nDLNKEVMENVYSFPGEVGLYIKDLKTGVVI-TYNENKPFASASLVKLPIMAATYQAIE -DGNITLQEQLTLTRSLKAAGSGTLKMRRGTKFCVSELLYHMITESDNTATNMISNKL-GY -GYINWVFKNLNMEVTRMDRGIMDLRMR-KYGVENYTTAREMGDILEKIYNKQLISERASD -EMLTILSQQKH-KDRIRRFLPKNLNVANKTGLLRD-ICHDAGIVFTDKGD-FIVCVLTSD -FGPSYRVAKNLIGEVAYKTYRC- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=UPI0005196F2A ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Niastella yeongjuensis TaxID=354355 RepID=A0A1V9FC05_9BACT ---KLKDQISSKLAEQPGNFAVAFKDLSTGEML-LLNDQDFFHAASTMKTPVMIEVYKQAA -AGRFSLNDSFALKNSSIVDNSAFSYQHLGEKYSLYNLVYDMIIRSSNLATNMVIELV-NA -HNVTQTMRQLGADKIQVLRGVEDSK-AFDKGLNNVTTANDLLVIYEKMAQGEIVDNASSQ -AMIKILLNQEF-NDIIPARLPKDVKVAHKTGNISH-VLHDSGIVFLPNGKKYVLVILSKN -LQN-EANAKKAMAEVSEMIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. animalis TaxID=76859 RepID=A0A0M4RIX7_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGDKKVLSASMIKLLILAELMKKVF -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELRLKETFLGRKMMDIEAR-KKGYDNYTCADDISLLLKLIYQEKLINKKASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWIGDKA-YILAVLTNG -MP--NFQCKQTIGKISKFVYDK- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9BHP6_9BACT ----ARGEIEKRIQASGADVAIAFRTLDGKLEW-HVRADEPFHAASTMKVPVMIELFSQVK -EGKARLDEPLVVRNESIVDGSAYSYKAAGQTRTLEQLCEAMISVSSNLATNLLIEKL-GV -ENIQKTVGALHAEGMNVLRGVEDE-KAYEKGLNNTTTARGLEVLLEAIAEGKAVDGEASR -QMVEILERQKW-NEAIPAGLPPGTAVAHKTGEITK-IHHDAAIVYAK--RPFVLVILVRG -MA-DSKASAALMADITRALFQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. Soil768D1 TaxID=1736405 RepID=A0A0Q9VJ99_9BACI --qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDEPFQSASLIKIPMIIEGYRQSE -EKKIYLNQPVTIPPIEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH -DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -KILRAFDNQQL-RDKLPSLMGKGVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE -DMKSEDESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6KZU0_9BACT --kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK -DNVNAMLHSLGLPKTLLRRKMMDIAAARRG-DENIATPQEMVRLLEAIFKEKALDKQATA -EFIKQLSTLKQ--SYLPRYVPESVQVANKPGELE-GVRNDSGIVFAQNQ-PFAISVMTAY -DR-DEKAAERAIGEVALEAYRYf ->[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus scapharcae TaxID=1147159 RepID=UPI000225AB98 ---ELTDRIEEITNEAGGTWGIALYDMDTGISW-EKNSHDTFYAASVIKVPIMIAAFAASQ -KGELSLSEQLELKREDIVGGSGVLQHLTPGYFSIYDLITLMIIQSDNTATNMLINYI-GV -AEIQQSMREIGMEKSRFCHRLMTLEVD--REGQNEINAYEMTEMLVKLASGKIISAHASE -QMITIMKKQQI-RNALPSNIPKKWEFANKTGNIP-GISHDIGMLYVGNR-IFIASVLSKG -VE-D-IEAPKIIGNIGLEIYQY- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A3R8VHA0_PSEST -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QDDLTLDSRVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVTEGFGPITTLADVRRRYYVTPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537LUQ1_9BACT ----LQGVVEGAAARVSGRLGCCVCP-ETGTPWaIHRAEETFATASVIKAPIAVAVAAEVE -AGRLEWNQLLPPHLRDDAGDSGVIRHLSPLPYTVRDLVFLMLVVSDNRATNLLIDLV-GM -ERLNASFARAGWKHTSLARRLGDFEAR-ARGLENRSTPRETCDVFLRLLRGDLLSPGSRT -LLLEFLKAQVY-RDRLPARLPRTTAVAHKTGDMP-GVENDAGVLYLPAG-PIVAAVFTNE -LA-SDVEGRLAIQEIGRAIYD-- ->[subseq from] serine hydrolase n=1 Tax=Varibaculum timonense TaxID=1964383 RepID=UPI0009BB80F3 ---SLEKAIFSTLSELDGTIGMYFEDIVTGKKI-CINSEIEFSAASTIKIPLVLLLLTQAK -AGLIDLEEQIEIDKANRIGGSGVIKEISSSYPTIMDLAKLAIILSDNIATNQLVDIVGGV -KKVTEFCKSIGMDSTKFQRKMMDFES-LKLGKDNVTTPRDMGRLLKMLAEDDNRLSGVSS -KMIDIMKAQQL-NQKLPNLIPALVVVAHKTGELWR-AQHDVGIFILPGGHKYILALYTSD -LSS-DSKGVEVIAKLSKIVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Phormidium tenue NIES-30 TaxID=549789 RepID=A0A1U7J3W1_9CYAN ----LKGELEQLATLTPGTPVGFAVDLDSGQYV-DLGGAEPVASASTIKVPILVAFLQQVD -AGTLALNQSMALQEEYMANGSGTLREAVGTEYTALEIATRMIVTSDNTATNMMIASLGGI -EALNQTFAAWGLEHTVLRNALPDLDGT------NTTSAKDLTLLMALIDQGGLLTPRSRD -RLFSIMQRTEN-GSLIPSGIRDGSLLANKTGDIS-AMLGDVALVDVPNGKRYALAVLVQR -PAND-GRASELIRRMTETI---- ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E4A0Y8_9BACT ---QLRKQIEQELSKQPGVFAVAFRDLATGNEL-LVRERDVFHAASTMKTPVMIEVYKQAA -QHKLALSDSLTIKTESIVDGSTYSYKAIGTKRTLEALVYDMIIVSSNLATNMVIERV-GA -QNVTQTMRDLGAKDIQVRRGVEDSKA-FAQGLNNTVTAYDLMVIFEKIAIGKAVNPQASN -AMIKTLLDQKF-NDAIPGKLPRDVKVAHKTGSIA-GVRHDSGIVFLPDGRKYVLVLLSKD -IK-DDKATVATMATVSELIYTY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044E1E4D ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=2 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5BBCE ------------------------------------------------------------- --------------------------------------------------ANLLLTTIGGP -KELTAFLHNMGDHVTRLDSWEPELNEAIPNDERDSTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides sp. An19 TaxID=1965580 RepID=A0A1Y4JNU6_9BACE ----LTDSISRIVSACPGEVGVALI-VNNSDTV-TVNNKSIYPMMSVFKLHQVLAICNRFD -QDGLSLDTSLTVRREDLDPWSPMLKEHREPLLPVRDLLRYTLIQSDNNASNLLFERLVSV -AETDSFIATIPRSSFRIAYTESEMAADHAKAYANCTSPLGAAMLIHRLFTDALVSREKQD -FIMKSLGECTTGKDRIAAPLKEGISIAHKTGSGYTEAHNDVAYICLPNGVNYALAVFIKD -FKGNESQASQVAARISAAVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4F2L8_9BURK ---PLERALARVEADSGVRIGVHVRDLDTGAFA-SLHGTEPWYLASSVKVPVAIAVLRGVE -RGDFTLETPLTLRAADYVDGAGPTNSRPVGTLTVRYLLEQMIIYSDNTATDMLIGLV-GI -GTVNAVVQSLVPRGFGRITSLADVRRTYYATGLNSGHLDAYADLLQTLVEGRALDARHTA -YLLSVMERVKTGTQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRSGPRLLVVACTR -GEPSTARSDRALRQVGIALC--- ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus timonensis TaxID=1871002 RepID=UPI0008DA9961 -----------------GPFQIYFTNLSTNQSI--YRGSETMPAASMIKVFILAKAYEDIQ -SGSLRRNETFTLTPDNVVGGAGILQGRGYGTVSLQEAMDLMITESDNTAANLLIDRL-GM -DRINSYMQSHGYTHSVLRRKMMDTEA-MREGRENMTSTRDIALLFKRLYRGQCVGPAQDR -EMLEIYKRQTD-NDSIPGALPKGTVVAHKTGEVSD-FRHDGGIVYTPKGD-YVLVIFTGN -YTPY-ETMAD------------- ->[subseq from] Uncharacterized protein n=2 Tax=Senegalimassilia anaerobia TaxID=1473216 RepID=A0A369L8W6_9ACTN ----LRDALEQAVEAHSGAYAVTCASADGSWSV-DVNGDKPFVSASIIKLAILGTLLDQAQ -SGVLSLDGTVTVSPSDIVGGTGVIQASGAGEYTYRQLAAYMIQDSDNVATNLIIDAV-GM -PAVNEYASEIGLTQTVLNRRMMDFAA----GDENYTSANDVARMLQLIYQGKLVSPDMSE -FALDLLKGQHD-DAGLLEGLPAGSVFAHKTGTLD-GVFNDGGIVLD--QNPYAIVMLSGD -AERS--QAQACMVDIAQAA---- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=UPI001143025C -----ENQIQDLIQKTPYKVHLFVKDPKTDQFLfSHQLEESFSSASIIKVPILLAVLAYTG -KHNISLHSSLTITPTDWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE -LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYGSSFD-YLIGIFITN -VT-DNDLARQLIGRLSKVVYDH- ->[subseq from] Uncharacterized protein n=1 Tax=Olsenella sp. oral taxon 809 str. F0356 TaxID=661087 RepID=G5F2U5_9ACTN ----IQAAVEAALAGHSGSAYVAYESVDGSTTGfSLGGEERVPSASMIKTAVMATLLQEAQ -DGRISLADGTILRGQDRVEGSGVVQDMRAGTLSYGQLAAYMIGQSDNMATNLLIDAL-GM -DAVNEECQRLGLADTSLRRKMMDTAAATS-GRENYTSASDQARLLLMVARGELVSPEASE -RALGWLEDQAD-TRGLAQGLPDGVAFAHKTGSLD-GVRHDGGIVLG--DHPYVFVVMTTG -MD--QGQADALMARVSTAVWE-- ->[subseq from] Uncharacterized protein n=3 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q7TIJ0_9BACT ----LKARVQARILQTPARVGLYYRDLTTGDSL-TVGSDVRFHAASTMKVPVMIQLFRDRD -AGLLSLDDSVTITNTSIVDSSPYRYKRLGQWASIRQLIELMETVSSNLATNLLIAKV-DA -KRANATAHALGADSILVLRGVEDD-KAYRAGLNNTTTARDLGMLLAAIANGKAASAASCR -EMLAILGRQQF-NEGIPAGLPPGTTVYHKTGWIGQVVYHDAALVEPPNGGRYVLVVLTGA -IQKD-ADAHAAVRDLSKLVFD-- ->[subseq from] Serine hydrolase n=1 Tax=Lewinella nigricans DSM 23189 = NBRC 102662 TaxID=1122177 RepID=A0A2D0N8R0_9BACT ---DLEQQVKEEFDQGDGTFAMAFMDLTTGDQL-LINARESFHAASTMKTPVLIELYKQSE -AGKFSLEDSILVKNESIVDSSLYSYDVVGSKRTVADLAYDMIIVSSNLATNLVIDLV-DA -RKVTQTMRDLGAPDIQVLRGVEDIK-AYELGMSNSTTAYDLMAIYEKLGRGEVVSPEASE -AMIDILLDQKF-NDIIPAHLPEAVKVAHKTGSIT-GVHHDSGIVMLPDGRKYVLVLLSKE -LG-DFAAGTELLAGVSKMVYDY- ->[subseq from] serine hydrolase n=1 Tax=Pygmaiobacter massiliensis TaxID=1917873 RepID=UPI000C79DEAF ----LKNEIESYLATRPGKVAVVWRDLISGGDF-SIAGKTRFVSASTIKLLIMAELLDQIA -AGRRSLSDHILLTQARVTGGDGILKERPGHSFALEEILTLMIIVSDNTATNLLIDLL-GM -DAINAQARKLRLREAQLGRKMMDTEAK-RQGRENYICAEDMAKMLELIYRGTLVDEKMSR -TALEILLRQQQ-TGRLQLYLPEEIPVAHKCGDLDC-LEHDGGLILVEGH-PYLLVVLTEQ -NP-SNREGRETIGTISKMVYDA- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XDV2_9BACT ----------------GRDVGLVLLPLDGRDAV-MVEPDKTFHAASTMKVPVMIELFRQAE -EGKLRLEDPLPIVNESIVDGSVYHYKAVGKTMTLRELCEAMITVSSNLAANLLIERV-GV -ENIRATVARLGATGMDVRRGVEDQK-AFDQGLNNTTTARGLAVLMQKRAKGQAVSPRADA -EMVAVLKRQKF-NDAIPAGVPEATPIAHKTGTITK-IHHDAAIVYGP--RPFVLVILVRG -IQE-QKESAALMAAISREVWN-- ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T181_9BACT --tALQNELTDFVKDKDARIGMAVI-IDGKDTV-AVNGKEDFPMLSVYKLPIALALADNYR -VKGLDFSEPIAIAKEDLHLYSPMTGRLLASSMPTREILNYMLQQSDNNASDLAVKKLGGT -ENVMKWLSKSGLSGVKVVSTENEMHINPELSYKNSSTPIAMARLLDKLDTE--WNDSLSK -EIKQMMETCKTGENRLAKLLPTNAVTGHKTGTGFIMAVNDVGYVHLSNGHRYSIAVFIAD -AHYDMAESENIIAQISEMVWR-- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI0004D3B9EB -----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTE -KHNISLHSALTITPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFCQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE -LVIDILSRQRV-HEGLKRYLVDDVKLAHKTGGLDT-VDHDAGIVYSSSFD-YLIGVFITN -VT-DNDLARQLIGRLSKVVYDY- ->[subseq from] Serine hydrolase n=2 Tax=Halomonas sp. 1513 TaxID=1883416 RepID=A0A1P8R451_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- --RVTAFAERLGVAREELKLDTDAAFDAYEASALNGGTLVAFGELLATLARGGGLSAASRE -ALLAVMRRTRSGEARLKAGFGDDVVYAHKTGTQHR-RTCDAGIAQRGGQRQVAVVACTRG -P-LDVVPHERLLAEVGAAI---- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5VKA8_9BACT --kKLETRVEEIAARLDGVMGVAILDLTDGQVL-LRNADRVFPAASSIKLAILLELYRQDQ -QGKAKLDDIYAFDPKDLVEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAAANILYDRV-GR -DNVNALLRGLGLSKTTLRRKMMDIAAARRG-DENVATPQEMIRLLEAIYKEKALNKQSTA -EFIKQLSTLK--DSYIPRYLPEGVQIANKPGELE-GVRTDSGIVFAPNR-PFAISVMTAY -DRDEKA----------------- ->[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:1058 TaxID=1262918 RepID=R5CN93_9BACT --qTAEEAITRLARGRQATVGAAWIS--GGREH-AVNNRGDYPLMSVFKTHCAIAALRRMQ -REGIPADTLIRVKAAEMTPYSPLAKMHEGEDMRFDSLLYYSIALSDNNACDVTIRMAGGI -EGVNAEMEAIGLAGCALTETEATMAADPQRSYNNRSTPLSVAVLFRKLYEDGILGGDYDR -LMKAALEATQTGPDKMKAALAPGMTLAHKTGTGFMTADNDAGAVTLPDGRRIYIAVLVKD -TRLGTKENARLIREITEAIIR-- ->[subseq from] Serine hydrolase n=1 Tax=Niastella populi TaxID=550983 RepID=A0A1V9G892_9BACT --nKLKNQVNSKLAEQPGDFAVAFKDLTTGDSL-FINEQTFFHAASTMKTPVMIEVYKQAA -AGIFSLNDSFTIKNESIVDSSSFRYRHLGEKRTLYELVYDMIISSSNLATNMVIELV-NA -RNVTQTMRQLGADRIQVLRGVEDSK-AFDKGFNNITTANDLLVIFEKMAKGEIVDSTACQ -AMIDILLKQQF-NEVIPARLPKDVKVAHKTGNISH-VYHDSGIVFLPDGRKYVLVLLSKN -LK-NEEQAKKAMAEVSELIYKY- ->[subseq from] Serine hydrolase n=1 Tax=Litorilinea aerophila TaxID=1204385 RepID=A0A540VDX5_9CHLR ----LLHNIQAAVAASGAHMGIAIHHLESGETL-ELNADEPFPLCSVLKIPVLVEAFRQLR -EGRFRLDDRWELTLAEKNLPSGVLVFLQDGLPTVQDLLTLMIIISDNTATDMLMHRL-GV -ARINQTMHELGLADTHIALTIREIFDFSTGPDNDVGTPRDMTRLLTLIFRGEVVDREACD -QMLHILLQQQL-NTRLPLFLPEGVPFAHKTGTLS-GIRNDAGILYASPTSHVAISVFSRW -DARRTTAIDEAFGRIGRLVYDHy ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI0011A8FC58 --kKLVSRIQDLIERSEGIWGIVLEDLELDERW-ELNGEELFYAASVIKVPIMVAVFSAAE -KGEFKLSDQLLLKEEECVGGSGVLQHLTPGTLSIQDIVMLMIIQSDNTATNILIDLV-GV -EAIAQTMKEAGMEKSTFYNKLML--STPPPKGYNQITPNDVAKLLKSLTTGTLVSPHASE -QMIDIMKKQQM-NECLPEKLPSVWELSHKTGWIP-GTRHDVGIFFVEGRK-LIATVLSKD -ED--DLLSKGILNEIGEEIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EHP4_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQTLARTLQVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. animalis D11 TaxID=556264 RepID=D6BHN0_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSEHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINQLGKELRLKETFLGRKMMDIEAR-KNGYDNYTCADDISSLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLLSDIKIAHKCGDLDN-LENDGGIIWLGNKA-YILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7804A9 -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRVE -QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A2D8IFF2_PSESP -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QGDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -ERVNAVTRELVPEGFGPITPLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase n=2 Tax=Firmicutes TaxID=1239 RepID=A0A0A3J0I7_9BACI -----KEELERLIDSVDYNIHLFIKRAKAEDFIfAKQLDEVVSSASLIKVPILIAVLELIE -RQNISLQMEVEIKQNHKVEYSVLTEQDSD-KSTLYELLVWMIITSDNTATNVLIDFL-GM -EECNAFFKKIGLTRTKLQRKMMDFDS-LQKGVDNVTTARDMANLFTRIYKQDLLPLQFSQ -LALDILSRQRI-NDGLKRYIIENVKIAHKTGNLDT-VSHDVGIVFHEKLD-YIIGIMITD -IN-DAEEAKKCIGLISKIVFQYf ->[subseq from] serine hydrolase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=UPI0009E4E25D ---QLRKQIEQELSKQPGVFAVAFRDLATGNEL-LVRERDVFHAASTMKTPVMIEVYKQAA -QHKLALSDSLTIKTESIVDGSTYSYKAIGTKRTLEALVYDMIIVSSNLATNMVIERV-GA -QNVTQTMRDLGAKDIQVRRGVEDSKA-FAQGLNNTVTAYDLMVIFEKIAIGKAVNPQASN -AMIKTLLDQKF-NDAIPGKLPRDVKVAHKTGSIA-GVRHDSGIVFLPDGRKYVLVLLSKD -IK-DDKATVATMATVSELIYTY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5T5C8_9BACT --kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKARLDDLCTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK -DNVNTMLHGLGLSKTMLRRKMMDIVAAQRG-DENVATPQEMVRLLEAIFKEKALDKQSTA -ELIRQLSTKK--DSYIPRYLPESVQVANKPGELE-GVRTDSGIVYAQKR-PFAISLMTAY -DR-DERAAERAISEVALEAYRYf ->[subseq from] Beta-lactamase class A n=1 Tax=candidate division TM6 bacterium GW2011_GWF2_33_332 TaxID=1619080 RepID=A0A0G0CP64_9BACT ---DIQKKVQEICTSVPGEMGVAALHIESGRRV-EFNSHEAFPMASSYKIPIALSCLSLVD -SGRLSLNQHVLF-----VGRSKKTPNVKKVYVTLRKCIELMLARSNNTTSDRVLEMTGGP -FAVNSWLSRHQIYGMRIDRPVLKMRKKFYVDERDTTTPRVMVDLLAQAFEGKLVSERSTS -FLFSCMAKCCTGSMRMVHLLPKHVKVYHKTGTMD-GIISDVGVITLPGGGHLVLAVYSNK -SMRLTDDRALAIARIARSLFDYf ->[subseq from] Serine hydrolase n=1 Tax=Larkinella rosea TaxID=2025312 RepID=A0A3P1C1N4_9BACT --eQLKQQIELEFKKQPGRFAVAFKDLTTGNEL-LIREQEVFHAASTMKTPVMVEVYKQVA -QKRFSLTDSILIKNQSIVDGSLYSYTEVGKKRTLYSIMYDMIIVSSNLATNLIIDLV-DA -RKVTQTMRELGIKNSNVLRGVEDTK-AFQKGLNNTVTAYDLMILFEKIATGKAVSPQASE -AMIKVLLDQHF-SSVIPAKLPKDVKVAHKSGSFAT-VRHDSGIVYLPDGRQYVIVLLSKE -MP-DDAAATETLATVSGLIYQY- ->[subseq from] Transpeptidase domain-containing protein n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A359LPX7_9BACT ---TLDERVRAAVTGFQGTVSLYAKNLATGAEY-GLRADERVRTASTIKLPIMAAVFAAVE -RGQARWDERIKMTREDKVSGSGVIRELADDSLTLRDLVHLMIVVSDNTATNLVLDRF-TA -DFVNEELDRLELRQTRSLRKILGDGREFRRFGIGVSTPREMARLLEKLHRGEAVSAGASK -EMMAILKRQQY-KDGIGRRIEEE-KVASKSGALD-ALRSDVGIVETARG-PVALAITVDG -MPSPENAGNKLIGRLAELIVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_64_13 TaxID=1797948 RepID=A0A1F9UWP7_9BACT ---ELNRKVREQSERFPGVSGIVIKDLRRGWTI-EHNPSRLFPSASLVKLPLMVALYEADL -RGEISLDQSFPILRHLRARGSGTLKQRPGTRLTIHEFISRMITESDNTATNVLTNLF-GL -DYYNSQFLSMGLSRTNFSRTIMDLRQR-DRGIENYTTPRDMARLLEWIYRGRF---SGSR -EMMDILKAQKI-NDRLARGIPGDWTIGHKTGLMRD-SCHDVGIVFAPGSD-YVICALTTD -AR-SSRRAKKFITSLSKLTAEYy ->[subseq from] Beta-lactamase enzyme family n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=A0A023X3Z3_9ACTN ---------VEVVERYPGIVGFYALDLRDGSGF-GVRPDEEFFSASTIKVAVMAAVYRKID -AGELEYSDELTTTDEDWAAGAGWLRWTPGAKATVEDALWLMMTESDNVATNVLTRAVGGP -EYVNEVIRDLGAKDTELFWKLTSERAAVP-ELDNNTTPRDMTTLLSGIYNGEGFKDFSRR -EMVDLMGQNNL-EYWLEGGLPPEVKAANKGGWLD-GSYNDVGIVRYEES-PYALAIYTMN -GP-VIEEGQGVLSEVSEAVW--- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. X1(2014) TaxID=1565991 RepID=A0A077JB23_9BACI ----LKEKITKDLVDFKGRVGVAIEI--EYERY-EFHSGEVFPSASVIKVPILIECLKQSE -LGKIDLDEFIKIT--DRAGGSGVLQALSTNLLTIKDLMTLMITVSDNTATNMLINIV-GM -DQINQTMEEIGLHSTRLQRKMMDFAAK-EKGLDNVTSPSDMVKCLKIIHEEDFLSANSRR -MALDILHFQQFHDKLLAMINTDKVFTANKTGSLSN-VENDCAIIKAGSKT-AYVAVLTDQ -LP-DPYEARQVISRIGKHIYN-- ->[subseq from] Serine hydrolase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A6A9R223_PSEST -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QGDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GV -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGARRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A414XI42_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGENGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Caloramator quimbayensis TaxID=1147123 RepID=A0A1T4WDN7_9CLOT -------NIRGIMEKHDIKYSLIVKNLSTGEML-NINGDTSIPSASTIKVFIMAEAFRQAK -EGKISLKERIKVDKSYHVPYSIISLLSEDNTYTIMDLITLMIIQSDNTSTNVLIDIL-GM -GKINDYIKSLGCSLTVLERKMMDFIAR-DKGLENKTCARDLTLFMELLYKGEVVDESSSK -IMMDILKHQLD-TSMMAYFIPEEVSIAHKTGEVSR-VDHDFGIVFLDNLD-YIFTMMTYD -VK-SNNDARFAIAQVSKEVYDYf ->[subseq from] Beta-lactamase n=3 Tax=Bacteria TaxID=2 RepID=A0A127STN6_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGDNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R6DLM7_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Anaerosphaera massiliensis TaxID=2040296 RepID=UPI00126012C3 --eNLKGKIINMLSKRSGNISITFYDLDEKEGF-SIRGDKKAPSASMIKLLIMIEVMRRVN -NRELFLNEKYKINEDMKVGGSGILKDLEDGHFSLRELIILMIIVSDNVATNFLISLV-GM -DNINTTGKNIGLKNTILERVMMDIDAT-REGRDNYTSSDDVALIFNKIYNQELISEELSQ -IMLGILLKQQY-RDRLQRYLPEDIKIANKSGDLDY-LENDGGIFFRKNK-NYILVVLVNS -AI-SNYEAKESIGRISEIIYEE- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus fusiformis TaxID=28031 RepID=A0A1E4R5Z3_9BACI -----ENQIQHLIQKTPYKVHLFVKNPKTEQFLfSHQIEESFSSASIIKVPILLAVLAYIE -KHNISLHSSLTIAPADWVDFSVLREQRMT-QSTLYELLVWMIITSDNTATNVLIDVV-GM -EFLNDYFRQIGLKETMLQRKMMDVER-LAMGVDNFTSARDMAHLFTRIYQQDLLASPYNG -LVIDILSRQRA-HEGLKRYLVDDIKLAHKTGGLDT-VDHDVGIVYSSSVD-YMIGVFITN -VTEN-DLARQLIGRLSKVVYDH- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4DUV7_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQTLARTLQVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPSHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. AWRP TaxID=2212991 RepID=A0A3T0LVN8_9CLOT -------KILAAIDLKKLNCAFVIENLKTGEKI-AYNENIVVPSASLIKIPIMMEILNQVK -EGKLSLKQRITVEDNVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM -DNVNNYVKNLEIKNTVLQRKMMDSQAR-KEGRENRTTAADMAKFFEIIYKGEKIKESYSV -IMKNILTAQLD-NSVMRLNIPDDTLIAHKTGDLD-GISHDAGIVYLPNAD-YIFCGLTWD -AV-TNNFARETIGKISKIAYDYf ->[subseq from] Serine hydrolase n=2 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534GPQ1_9GAMM -------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV -ENIRAGVHALGADGMNVLRDLEDAKA-FEHGLVNTTTAQALLALLEAIARGQAVDRESSR -QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLAS--RPFVLVVLTRG -LEN-PKESTALIAEITRELYR-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A229I6J2_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGGNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon TaxID=2026714 RepID=A0A2E8EI86_9ARCH --eKLLRRLEAITNDFNGVMGISIKDLVSGDEF-NINENEVFPVASSIKIPLLMEFFRQVK -SGMLDLYSEITIQEGNKTKGSGVLNELGDGTMSLQDLATLMIIVSDNTATNMLIDKV-GM -DDVNLLMQNLGLMETKLQRKMQDYQAALSG-QENISTPFEFMKLMECLFRKKGLDAWVCE -QTLSVLKKPKI--TAISLGVPMELEIANKPGGMI-GVSCDAAIIFQPNR-PYVIIILTKE -ISLSDARAGKRITEVSSLVYEYf ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. NIES-970 TaxID=1827144 RepID=UPI000BBA56C9 ---------AAIASEPTLDASLLFVDLDTGEYL-DVAGDRALSAASTIKIPILVAFLEAVD -KGEVNLDDTLTMTQEVIGGGSGGMQKTPGSTYSALYTATEMSVNSDNTATNMIIEVLGGN -TALNAKFQQWGMAQTQVNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSMRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGT-IIGDAGIIDLPNGKRYVAAIFVER -PYND-PKGRELLHKISRQFYDH- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. NKBG15041c TaxID=1407650 RepID=UPI0011DD353A ---------AAIASEPTLDASLLFVDLDTGEYL-DVAGDRALSAASTIKIPILVAFLEAVD -KGEVNLDDTLTMTQEVIGGGSGGMQKTPGSTYSALYTATEMSVNSDNTATNMIIEVLGGN -TALNAKFQQWGMAQTQVNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSMRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGT-IIGDAGIIDLPNGKRYVAAIFVER -PYND-PKGRELLHKISRQFYDH- ->[subseq from] Class A beta-lactamase n=1 Tax=Nocardia panacis TaxID=2340916 RepID=A0A3A4KWJ9_9NOCA ------------------------------------------------------------- --------------------------------MTLLEIAAAAVTRSDNAAGNLLLRELGGP -QRFTAFLRSLGDQAARLDDNEPALGAFRPGDDRNTTTPAGLAADYRAVTLGAVLGTPERV -QLIQWMREAKTGDSRIRAGLPSDWITADKTGTGGYGCVNDAAITWPANGAPLVIAIQACG -NGENGAADETLFPEVTRLVLD-- ->[subseq from] ClassA_beta_lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059X5A8_9BACT ------------------------------------------PMLSTVKFPIALAILYKVE -QGELAMKQKLLIKKAHLREWSPFRKLHPNGNITLEEAMTWMVAESDNNLTDVLLRLIGGT -ETVKEFMDS---EGFIIKNNEADMHKDWAAQFVNKIRPTVAVQVLQEFDQQRILNPQHTK -WLYTTMAGSKTGDKRLKGKLPENIVVAQKTGTSFTGAINDIGIIELPGNKKIYIAVYVRD -CAEPFETGEAIIADIAKVTYDYy ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax citrulli (strain AAC00-1) TaxID=397945 RepID=A1TIK7_ACIAC ---PLERALARAEADSGVRIGVHVRDLETGASA-SLHGTEPWYLASSIKVPVAIAVLRGAE -RGDFTLDTPLTLRAADYVDGAGPTNGRPGTPLTVRYLLEQMIIYSDNTASDMLIGLV-GI -GTVNAVVQSLVPRGFGRITTLADVRRSYYATGLNSGRLDAYADLLQALVEGRALDARHTA -YLLSVMERVKTGPQRIKAGLPPGARFAHKTGTQR-ARTCDSGLVTVPRAERRVLVVACTR -GEPSTARSDRALRQVGIALC--- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium M5B4 TaxID=2054928 RepID=A0A2N5JQL6_9CYAN ----------------ELNLHLMVYEPDQGGYV-DINAATPTASASLIKLPLLVAFLEQLD -LQTIALDEMLQLTEGDKAPEAGILQDQPGTKISALEVATLMITESDNTATNMMIKRLGGI -EVINERLDKWGMKQTRFRNILPDLQGT------NTTSAKELVELFSKVEQQQLLSLRSRD -LFMDILSQTKN-NSLIAEPIGEKSRIRHKTGTIAN-LIGDVAMIDAPNGRRYFLAVMVRR -PPED-PSAEELIRKISATVYSHf ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI001290C3BC ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A127D529_9BACI --qTIEHDILALVESFNGKIAYKIEN-GLGETI-GYHVNESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTSTNMMMSLL-GI -DEINRCIKELGLKNTILERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -RIMRVFDNQQI-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -M-KSEEESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A521GJF0_9BACT ------DSLTAYIRSLTVRVSVALESLASSERF-YYRADERVPSASLIKVPIMVAAMTAAQ -AGKLDLDEIHILTDSEKVGGAGILQTYPNRSISYTELVRLMITISDNTATNILISDL-GR -EAINTQMQSWGMTQSRLNRVMMDTLAA-RQGRENYVTAREMNQLLTKIHEHKLLTPALCE -QMLTFLKQNED-TLTIPHLLPPQVVVAHKTGVLAY-VRGDAGIVFAP--RPFVLTVLVEN -AG-TEAAGEQTIADLAFLVWK-- ->[subseq from] serine hydrolase n=1 Tax=Luteimonas sp. LNNU 24178 TaxID=2605430 RepID=UPI0011EFC41C ----LRTRIEAADARFPGEIGVYVHHLGRDESF-SFRAEESWYLASGIKVPVAIAVLRRVE -RGELRLGDRVRLRADDFVDGAPTNAQRVGTPLRVDWLLEKMLVYSDNTATDVLIRSV-GV -DAVNAVATELLATDDLLITTLADVRRAYYETNVNAAPLRDFGHMLATLSDGLALGPEGTA -YLLDLMSRVKTGAKRIKAGLPPNAVFAHKTGTQHR-RACDLGIVTMPDGVERVVVAACAR -GAASNAASERALREVGVAVT--- ->[subseq from] Beta-lactamase n=1 Tax=Hyalangium minutum TaxID=394096 RepID=A0A085WKX8_9DELT ---------QRIIQVKGASVAVVYQDLGDLKDSvLIEADRSFHAASTMKVPVMVEFFRQVD -AGTLSLDQPIPLVNQSIVDGSPYAYEQLGKSVPARELIQRMITRSSNLATNSVIALV-DA -KRATQTLRTLGAQQMTVLRGVEDGK-AYQQGLNNTATAKDLATLLAAIERGKAASDRSTE -AMRSILLAQEL-NEEIPAGLPPSTRVAHKTGQIS-GVLHDAAIIYPSGRAPYVLVVLTSG -IP-DEKVARSLIVDISRAVYAH- ->[subseq from] Beta-lactamase class A n=2 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A370FRT6_9BURK ---RMASAMQQLGGASQTGIGVYVLDLASGQSF-GHRADERWYLASMVKVPVAIAVLQAVE -RGEISLDTTVTFRAGDRVDGAGATLRQPLGSLSVRWLMGQMIIYSDNTATDMLIDLV-GL -QAVNGVAQTLAPRGIARITPLAEVRRAYYAEGLNSGRLDAYAQILVALAEGRALGAEATQ -TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPARHPVVLAACVRD -AP-SLGRAEHLLAQTAAALC--- ->[subseq from] serine hydrolase n=1 Tax=Halomonas sp. BC1 TaxID=1670448 RepID=UPI0009BC907E ------------------------------------------------------------- ------------------------------------------------------------- -----ALARTLGVSSSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ -TLLEVMQRTRSGTQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG -PL-ALSAHEQALTRVGEALHD-- ->[subseq from] Serine hydrolase n=1 Tax=Fibrisoma montanum TaxID=2305895 RepID=A0A418M338_9BACT ---------------TKARVSLAVESLADSTPSfYHHADERVPSASLIKLPILIEAMERIK -AGQLDPDEIHILTDSEKTGGDGVLKTYSHRSIAYRDLIRLMMIHSDNTATNILINEL-SQ -NAINQRIRSLGLSATQLNRVMMDTVAA-RQGRENYVTAREMNHLLKRMYHHQLATPALCD -QMLDILRQNED-RQTIPRLLPKTVAVAHKTGILSY-VRGDVGIIYAS--QPFVLSVLVQG -VP--TAEAERIISEIALMCYNQy ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3M2EAQ0_9BACT ------------------------RDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE -AGRFSLDDSLLVRNESIVDGSAYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA -DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLLDALRRGAAVSPEADR -TMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG -VE-DQARSAELVAEVARVVHE-- ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteria bacterium CG2_30_36_16 TaxID=1805221 RepID=A0A1J5FXT8_9BACT --eKLTAEIKNKLDSAKGIYGLVYKDLQTGENI-FYNEKENFHAASTMKTPVMIEVFKQAE -EGSFSLDDSILVKNESIVDSSLYMYQFIGGKKTIRQLVYDMITVSSNLATNILIDLV-HA -ENVMRTMKEIGAENIKVLRGVEDIK-AFEKDLNNTTDAFDLMLIFEKIAIGEIISEKACS -EMIDILLNQEF-NSRIPALLPSDVKVAHKTGSIT-GIEHDGGIVILPDGRKYILIILSKG -IQGS-KLKTNIQAEVSRMIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Variovorax guangxiensis TaxID=1775474 RepID=A0A502DZ80_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEALRNAMKVGKEDLKAKSDEAYDRYYQRNLNSATLVAYGTMLEKLVQGKLLKPDSTQ -KLFTAMKVDIFTNYRLQAGLPRSVKFIHKTGTQHR-RACHSGVINPQNGGDAIVVVTCAA -DLDEQREAGKVFERVGRAITK-- ->[subseq from] DUF3471 domain-containing protein n=1 Tax=Sphingobacterium olei TaxID=2571155 RepID=A0A4U0P445_9SPHI ----LKSRIQKLAKQPEGRFAYAFMDLQTGEQL-SLNAHELFHAASTMKTPVMVETFKQAA -EGKFSLSDSITVYNQSIVDKSKFSYVRVGTKITRHDLIFRMITESSNLATNIVIDQV-GA -KNVMKTMKSIGANDIQVLRGVEDTKA-FQKGMNNQVTAYDLMLIFERIAKGTMVNTEASK -AMIDILKKQKF-NSVIPAQLPKDVQVAHKTGSIA-GIFHDSGIVYLPNGRAYVLVLLSAD -VKD--NAVKKTLANVSLQFYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5JAU3_9ACTN -----------------NQAGATVRDLSGMQQV-AVNGTLRPKAASVIKLWILVELLRRVD -CGQVSLDERVLVTQADVVGGTGQLQEQIPQLATLRKLAEYMIEYSDNTATNVLINYLGGF -APMNALADSMNQRQTVLARKMLDTEAA-ARGEENYTSPDDVISLLGAVWDAQILTPASRD -LMIGFMREQTL-NSKIPAALPPGTPVAHKTGELPD-ASHDVGYYLIPGA-ETAVAFLTSG -PE---PSGADLVRRLARTVYDY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=UPI000B5AC25C -----------------NQAGATVRDLSGMQQV-AVNGTLRPKAASVIKLWILVELLRRVD -CGQVSLDERVLVTQADVVGGTGQLQEQIPQLATLRKLAEYMIEYSDNTATNVLINYLGGF -APMNALADSMNQRQTVLARKMLDTEAA-ARGEENYTSPDDVISLLGAVWDAQILTPASRD -LMIGFMREQTL-NSKIPAALPPGTPVAHKTGELPD-ASHDVGYYLIPGA-ETAVAFLTSG -PE---PSGADLVRRLARTVYDY- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI000DA55527 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRVD -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLD------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534ESA6_9GAMM -------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV -ENIRAGVRALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR -QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLAS--RPFVLVVLTRG -LEN-PKESTALIAGITRELYR-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A6A7VS45_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase, putative n=1 Tax=Synechococcus sp. NIES-970 TaxID=1827144 RepID=A0A1Q2TXL1_9SYNE ---------AAIASEPTLDASLLFVDLDTGEYL-DVAGDRALSAASTIKIPILVAFLEAVD -KGEVNLDDTLTMTQEVIGGGSGGMQKTPGSTYSALYTATEMSVNSDNTATNMIIEVLGGN -TALNAKFQQWGMAQTQVNNPLPDLEGT------NLTSAKDLAHLLARINQGEILSMRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGT-IIGDAGIIDLPNGKRYVAAIFVER -PYND-PKGRELLHKISRQFYDH- ->[subseq from] Beta-lactamase n=2 Tax=Archangium violaceum TaxID=83451 RepID=A0A084SPU3_9DELT ---------ERIAQVKGATVAVAYRHLGNSKESlYLEADRSFHAASTMKVPVMIEFFRQVD -ADKLSVSQELTLANQSIVDGSPYAYERLGKPVPARELVERMITRSSNLATNTVIALV-DA -KRVTKMLRSLGARQMTVLRGVEDGK-AYQKGLNNTATARDLATLMTAIEQGKAASPASTQ -AMRSILLAQEL-NLEIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPSGKTPYVLVVLTSG -IP-DEKVARSLIADLSRQVFA-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A646FR36_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Limnothrix TaxID=2632864 RepID=A0A1C0VBK0_9CYAN ---SLSDQFQKIAARYSLILHAAALDLDTGDFA-AWNDNRSVAAASTIKVPILVAFFQDVD -AGKIRLDEMLTMEARFVAPEAGTMQQKPGQKFSAIDTARQMIVISDNTATNMIMARTGGS -GPLNQRFQSWGLQGTSIRDLLPDITGL------NRTTARDLVQLTALINRGELVSMRSRD -RLLSIMRGTAA-NSLLPKGIGKGGEVAHKTGTLAK-LLADTGLVDTPNGRRYGIAVLAER -APND-PKAAEAIRDYSRAAYNHf ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M4U0_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -KRVQALARALDDADTFQVRTMDEAYDRYYQQRFNTATLTGYGAMLENLVRGKLITPQHQQ -ALFKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQLH-RACHMGVIEPQDGKSAIVVAACAE -GLDEQKEAGKAFEAVGRAITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. AM23-5 TaxID=2292054 RepID=A0A415VCF2_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGSNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI00044E2A66 ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKN-- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009DC0EB4 ---RMASAMQQLGGASQTGIGVYVLDLASGQSF-GHRADERWYLASMVKVPVAIAVLQAVE -RGEISLDTTVTFRAGDRVDGAGATLRQPLGSLSVRWLMGQMIIYSDNTATDMLIDLV-GL -QAVNGVAQTLAPRGIARITPLAEVRRAYYAEGLNSGRLDAYAQILVALAEGRALGAEATQ -TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPARHPVVLVACVRD -AP-SLGRAEHLLAQTAAALC--- ->[subseq from] serine hydrolase n=1 Tax=unclassified Synechococcus TaxID=2626047 RepID=UPI00117DF0D8 ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGDTSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma montaniterrae TaxID=1178516 RepID=A0A1P9X473_9BACT ----------------SARVSVAVESLMDSSVAfAYRADERVPSASVIKLSILLEAMERVK -AGTLDPDEIHILLDSEKTGGDGVLKTYSHRSIAYRDLLRLMLINSDNTATNIFINEL-GM -DAINARSQAVGLTQTRLNRLMMDTLA-VQQGRQNYVTAREMNVLLKKIYRHEVATPALCE -QMLDILKQTED-TATIPRLLPPGTVVAHKTGILNY-VRGDVGIVYAKN--PFLLSVFVEG -TT--TPEAEKIIGEVASTCYHFf ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N7F0Z2_9ACTN ------GQLQQVVDASTANAGVTVRDLSGDQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPAQVVDGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPASRD -LMIAFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-TSHDVGYYLLPSSQ-VAVAFLTSG -PM---AGGDETVRRLARTVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium neonatale TaxID=137838 RepID=A0A2A7MDV8_9CLOT ----LTNRINHIIKNSSADIAVLVKDLKEDKVIfKYNEDKKYVSASIIKVPIMIEALSRVD -LGEINLDDKFNIGDDNKVDFSVITEQDLK-ECTFEELIEWMIISSDNTATNVLIDIL-GL -ENINDRIKKLNMKNTLLERKMMDFK-AIEYGRNNYTSLNDMLIAMEGLYRGVLISSEMSL -KAIDILKNQRD-NFMLKRYIRDNVTLANKTGELDK-LNNDVGIFYTKNHN-YFIGIFVHD -VKKN-KDAYEIIGKISKEVYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A147GQS8_9BURK ---RMATAMQQLEALQRTEVGVYVLDLASGQSF-GHRAEERWYLASMVKVPVAIAVLQAVE -RSDITLDTPLTLRAADKVDGAGATLRQPGSALTVRWLMGQMIIYSDNTATDMLMNLV-GL -QAVNGVVKALAPQGIGRITTLAEVRRAYYAEGLNSGRLDAYAGILTALVQGKALHPDSMQ -TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPGTHPVVLVACVRD -AP-TLPRAEHLLQQTAAALC--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus simplex TaxID=1478 RepID=UPI0011DCFA0E --qTIEHDILALIEAFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLKRKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLMKESQE -RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -IK-SEEESRQVISKIGKLIYD-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Gammaproteobacteria (miscellaneous) TaxID=33811 RepID=A0A1Q6WM72_9GAMM -------------KKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV -ENIRAGVRALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR -QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG -LEN-PKESTALIAEITRELYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus chungkukjangi TaxID=1202712 RepID=A0A318TVJ5_9BACI -----EKNLQDLIEQVPYKVKLVVKDCAEPNQF-LFTKDDVFSSASLIKVPILVAVLEFLE -NKNESIHQIVKIAEENRVDFSVLSELEVS-EASLYELLVWMIITSDNTATNVLIDFW-GM -ENLNHYFKKIGLKNTTIQRKMMDFEQ-LEKGFDNLTTAREMAFLFEAIYRQDLLSKKSSE -LASDILSRQRI-QDSLKRYIADDVKVAHKTGSLET-VEHDIGIFFSKKR-PYIIGVFVTD -HTN-TEEAKSFIGKLSKIIYDHf ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F77AEA8 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIYSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. SYP-B805 TaxID=1578199 RepID=UPI0013ECF7AF ---TLHDRIMALVEKAGGTWGIVLEDVHTNERW-TLNEDHRFFAASLIKVPIMTAVFAEAY -AGKFAFEDKLKLRQEDLVGGSGVLQHMTPGTLTILDLVTLMIIQSDNTATNLLIDLV-GK -ESIREIMRKTGMTNSQFYNKLMIIPAELEG--YNEVTAADMARHLKLLATGKAISYDSCL -RMIAILKKQQV-RDSLPYHLPDPWELANKTGSVST-NEHDCGILYVGQSA-VIIAALSHQ -VP--TKTARDTIGRIGELVYNLy ->[subseq from] serine hydrolase n=1 Tax=Romboutsia timonensis TaxID=1776391 RepID=UPI0008DA4E09 -----QEKIIKLLEGCSGKIGFYYKDLNTQNEI-KYNEDVKFMAASIVKLPILIEALRRLE -SKDISDLEKIAITKYMKVPCGALTYMHDGIEVTIRDLCNLMIILSDNTATNVLIDRL-GI -DEINKTIKNLGLKNTILSRKMYDMESK-KLGNENYFSLSDMAIILESIHNETLISQSVSK -EIKTIMKEQQI-NHKIPYYIPEDVTILHKTGEAD-GITHDIGIVYSKN--PFIIGFASNE -TN--IQEFEDIIRKISRFIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Gottschalkiaceae bacterium TaxID=2527676 RepID=A0A521J512_9FIRM -----IENINRYIEGAKGEVSLVLKDLTNDKWIyTLNGNKPVQSASTIKVLIMVEALNQVL -QGKYSLNQIIDIREEYKVKYSMITDMTLK-SYPYLDLIILMNIVSDNTATNILIDLL-GY -ENINEMARKLGLKNTVLRRKMEEFK-AIKEGRDNYTSAMDMGVIMESLYRNLILTPEMCS -LALDILKRQKY-KDVLLRLISEDVKIAHKTGGLRN-LSHDIGIFYLDSVD-YLLGVFVTE -AES-DVEAKEIIGKISKVVYNYf ->[subseq from] Serine hydrolase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A410ML84_LYSSH -----ENQIQNLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTG -KHNISLHSALTITPTDWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFRQIGLQETLLQRKMMDVER-LAMGIDNFTSARDMAHLFTRIYQQDLLASPYNE -LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYGSSFD-YLIGIFITN -VT-DNDLARQLIGRLSKVVYDH- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SYJ5_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] CfxA6 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=C8C0D8_9ZZZZ ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A127SV59_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Latescibacteria bacterium TaxID=2053570 RepID=A0A3D2RNC0_9BACT ------KDLTSFAKTFAGVLGVSAVHLETGKQV-AYNSDHPLLTASTFKSILLVSLLERVD -AQELSLDDRIAFTTTKRVAGSGVLKLMKSDTFSIGDLAVLMITISDNTASQMLFDVV-GH -SRIRHTIDRLGLTHTQIPLSPKEMILA-YSSEGNVSTPADMCRLFRRIHNNEVLSCKSTR -IFLDIHKGQQL-RSVIPHRLPAGTVCAHKTGQFEL-VSCDVGIVYSNHG-PYAIALMAND -TRGDRIEVDTSLAALSRTVFDQf ->[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus sp. AC-3 TaxID=1680467 RepID=A0A1T5B7Z3_9BACI -----KQTITEILQNAPYNVHMFVKDCKTEQFFiSEKLEDTFSSASLIKVPILLAVLNYLE -SNNHSLEQEIEIAPEEWVDFSVISEQRLEQ-STIYELLVWMIITSDNTATNVLIDFL-GM -DALNHYFRQIGLKQTIIQRKMMDFEK-LAKGFDNTTSASDMALLFSRIYRKDLLSSAFNE -LTIDILSRQRI-HESLSRYLVDDVKLAHKTGGLET-VDHDAGIVYSRSGD-YLIGVFVTE -VTN-NDYARQLIGRIFKVVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium carnis TaxID=1530 RepID=A0A3P6JKA4_9CLOT ----LTNRINHIIKNSSADIAVLVKDLKEDKVIfKYNEDKKYVSASVIKVPIMIEALSRVD -LGEINLDDKFNIGDDNKVDFSVITEQDLK-ECTFEELIEWMIISSDNTATNVLIDIL-GL -ENINDRIKKLNMKNTLLERKMMDFK-AIEYGRNNYTSLNDMLIAMEGLYRGVLISSEMSL -KAIDILKNQRD-NFMLKRYIRDNVTLANKTGELDK-LNNDVGIFYTKNHN-YFIGIFVYD -VKKN-KDAYEIIGKISKEVYDYy ->[subseq from] Beta-lactamase n=2 Tax=Aquisphaera giovannonii TaxID=406548 RepID=A0A5B9VZB5_9BACT ---TLTSRLEPLIRAHKGKVAIAVKNLKTGEEF-HHRGAEVQPTASLIKFPVMVEAYRQAA -EGKVDLDARITLRAEDKVPGSGILTDHFSAGIALKDAIRLMIMSSDNTATNLVLDAI-GI -GATAATMESMGYPNTKIHSKVFRRDTRSKAYGLGSTTADEMVRLLEALHAHRLASPSACD -RMIEHLRTCDD-RDKFPKGLPYGTKVAFKTGSVDE-ARTAAGLIDCPDGT-VALCVLTCE -NQVPDNAGNVLCADVARAVFAHf ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A5P0WHB6_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Parabacteroides goldsteinii TaxID=328812 RepID=UPI00101E0606 ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNVSYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium ragsdalei P11 TaxID=1353534 RepID=A0A1A6AKR7_9CLOT ------EKILDVIDLKKLNCAFVIENLKTGEKI-AYNENVVVPSASLIKIPIMMEILNQVK -EGKLSLKQRITVNDNVKVPFSILNLLESGNSYTLKDIITLMIIQSDNTAANILMDLA-GM -DNVNNYVKNLEIKNTVLQRKMMDSQAR-KEGRENKTTAADMAKFFEIIYKGEKAKESHSV -IMKNILTAQLD-NSVMRLNIPDDTLIAHKTGDLD-GISHDAGIVYLPNVD-YIFCGLTWD -AV-TNNFARETIGKISKIAYDYf ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7A3836 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIYSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] class A beta-lactamase n=1 Tax=Muribaculum intestinale TaxID=1796646 RepID=UPI001093E7EF ---HIEDRLATYIAAQDARIGIAVI-IDGRDTV-SVNGNRDFPMLSVYKFPQALAVADYCM -KNGIGLSDTISIHGYEMKEWSPMRDRYGMGDLPLSELLEYSLRDSDNNACDILFRLIGGT -HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE -AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNGVNDAGYVFLPDGRGYAVAVFIAD -SACGMEETERMIADISDIIFQ-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A521MSD1_9BACT ---ELLKKIQARLSAETGEFALAFRDLQTKEQI-LWNDRTSFHAASTMKTPVMVEVFKQVA -AGKLSLTDSLVVKNESIVDGSLYTYRLVGTKVTLYDLVYQMIILSSNLATNMVIELV-DG -KKVTQTMRELGAKDMQVLRGVEDGK-AFEKGLNNSVTAYDLMILYQALAAGTIVNSKACE -DMIRILLDQRY-NDIIPAYLPKELKVAHKTGSIT-GVHHDSGIIFLPDGRKYVLVILSRK -LA-DADKATEAMARVSEMIYRY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A212NCV2_KLEPN -------KLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELTAAALQYSDNVAMNKLIAHVGGP -ASVTAFTRQLGDETFRLHRTDPTFNTDIAGDPRKLPSSWAMA------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000311DCAE ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Parabacteroides sp. AM17-47 TaxID=2293118 RepID=UPI000E941E34 ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNMLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Class A beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A2S6DA69_STAAU ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus butanolivorans TaxID=421767 RepID=A0A2A7W7C9_9BACI --qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDEPFQSASLIKIPMIIEGYRQSE -EKKIYLNQPVTIPPIEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH -DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -KILRAFDNQQL-RDKLPSLMGKEVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE -DMKSEDESRQVISKIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salarius TaxID=435906 RepID=A0A2N0U312_9FLAO --qELQKKIASIFEENHGDFAIAFKNISEEKDSiLINAHKNFHAASTMKTPVMIEVFKQAS -EGKFSLQDSLVIKNESILDGSSYSYEQIGQKRSIEDLVTDMIIYSSNLATNIIIELV-DA -KNVNQTMREIGAMDINVLRGIEDMK-AYEAGLSNSTTAYDLMLIFEALAKGKAVNAEADK -QMLQILQQQKH-TDLIPALLPENLKIANKTGWIT-GVHHDSALIELPDGKKYVLVLLSKN -MK-DMEAGTKMLAEVSKLIYDH- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000C9B9EB1 -----LARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVLRRIE -QDDLTLDSRVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATLFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGARRIKAGLPSDTVLAHKTGTQR-ARICDAGLVDQPGTQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacF n=1 Tax=Planctomycetes bacterium Pla111 TaxID=2528000 RepID=A0A5C5WFD3_9BACT ----LQAALAPMIDAHRGTVAVRFEHLVTGDAY-AYQADQQMPSASLIKLPVMMAAYEAAA -RGALSLDERCVFEEADKTPGSGLLSTHLSPGLSLRDMIRLMIGWSDNAATNVVIERV-GI -KAVNDLMDRLGCPHTRLNSLVFKRETLSAKYGLGVMCPKETVLLLKRLAEDDAAVKEMSE -EMREHLRACQS-TSMAPRLLPDGVVIAHKTGSVAD-ARCDAGIIESPVG-PIAYCVMTAD -NVSDENEAAKLIAEVTKAAYDRf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0009B2D86D ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=1 Tax=Bacillus butanolivorans TaxID=421767 RepID=UPI000E29783D --qTIEHEILALVETFDGRIAYKIEN-ADGDTI-SYHDDEPFQSASLIKIPMIIEGYRQSE -EKKIYLNQPVTIPPIEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMTLL-GH -DEINQCIKELGLKNTILGRRMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -KILRAFDNQQL-RDKLPSLMGKEVKVASKTGAIR-GVAHDCAIIRSEFQT--VYAVVLTE -DMKSEDESRQVISKIGKLIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Olsenella sp. DNF00959 TaxID=1476999 RepID=A0A134A1M2_9ACTN ----IQAAVEAALAGHSGSAYVAYESVDGSTTGfSLGGEERVPSASMIKTVVMATLLQEAQ -DGRISLADGTILRGQDRVAGSGVVQGMRAGTLSYGQLAAYMIGQSDNMATNLLIDAL-GM -DAVNEECQRLGLADTSLRRKMMDTVAA-ASGRENYTSASDQARLLLMVARGELVSPEASE -RALGWLEDQAD-TRGLAQGLPDGVAFAHKTGSLD-GVRHDGGIVLG--DHPYVLVVMTTG -MD--QGQADALMARVSTAVWE-- ->[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6IC55_9BACT --kKLEARVEEITSRLDGVMGVAILDLTDGRIL-LRNADHVFPAASSIKLAILLELYRQDQ -QGKAKLDDIYTFDSKDLVEDSQIMAGLSAGVLTNRDLAQFTVAVSDNTAANILYGRV-GR -ENVNAMLRGLGLSKVMLRRKMMDVAAA-RRGEENVATPQEMVRLLEAIHKEKVLNKKSTA -EFIKQLSTLKE--SYIPRCLPNGIQVANKPGNLE-GVRTDSGIVFVLNR-PFAISVMTAY -DR-DERAAERAISKVALEAYHYf ->[subseq from] Serine hydrolase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A516NL39_9NOCA ----AETRIRAVFADAGCTGWLHARRCDSGTEI-SLGGDERVVVASVYKLPLFVAFCRQID -EGRIDPTARITVTPSDCTPPTGIAALRDPVTMSLRDLAASMMTVSDNAAADVLLGEI-GL -AAVEELLDDVGLTRTRIVGGTADLHRAYDPSYTSATTPEEMTRFLHALWRGDILSPERTD -YARAVMRAQVW-QHRIAAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPAVDAAIAEVARIAVT-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI00118430A3 ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGVNEAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Leptolyngbya sp. DLM2.Bin27 TaxID=2480213 RepID=A0A5Q4EEY6_9CYAN ----LKGELEQLATLTPGTPVAFAIDLDSGQYV-DLGGAEPVAAASTIKVPILMAFLQQVD -AGNMALNQSLALREEHLAGGSGTMREAVGTEYTALEVATQMIVISDNTATNMMIAALGGI -EALNQTFVAWGLEHTLLRNPLPDLEGT------NITSAKDLALIMALIDQGGLLSTRSRD -RLFSIMQRTQN-DSLIPSGIRDRSLTANKTGDIG-GMLGDVALVDVPNGKRYSLAVLVQR -PNND-GRASELIRRMTETVH--- ->[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009EA9922 ---RMATAMQQLEALQRTEVGVYVLDLASGQSF-GHRAEERWYLASMVKVPVAIAVLQAVE -RSDITLDTPLTLRAADKVDGAGATLRQPGSALTVRWLMGQMIIYSDNTATDMLMNLV-GL -QAVNGVVKALAPQGIGRITTLAEVRRAYYAEGLNSGRLDAYAGILTALVQGKALHPDSMQ -TLLKLMEDVATGPQRLRAGLPPQARFAHKTGTQRR-RICDAGLVRMPGTHPVVLVACVRD -AP-TLPRAEHLLQQTAAALC--- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013E408B9 ------------------------------------------------------------- -------------------------KRQVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A5P0WVM9_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Synechococcus TaxID=2626047 RepID=A0A4P8X313_9SYNE ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 8807 TaxID=195248 RepID=UPI0008103457 ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. NKBG042902 TaxID=490193 RepID=UPI000694509C ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 73109 TaxID=374982 RepID=UPI0007458EB7 ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0009BAE9E1 ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A0H3YWR8_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium lianum TaxID=388280 RepID=A0A1M7Q6N9_9BACT -------------------VSLLIQD-EEGQTLfSQSADKRIPSASIIKIPILIALMEKVE -NREITLDARYSLQATDKVGGAGELQHLPDGSITFRYLAEEMIRISDNTATNILIRAI-EM -GYIQDWLKKNGYRDTQLNRLMMDFK-AIEEGRQNYTSPREINDILLNLWEGKWLKEDSRA -EIMHCLKGCAD-NSTIPSLLPAGTVVAHKTGTLDY-VRGDAGIILG--DKPLILSVFVEN -FE-SMEEAESAIGKIALKAFRDf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=F1DI15_KLEPN ------------------------------------------------------------- -TQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAVLSAPALQYSDNTAMNKLIAQLGGP -GGLTAFARAIGDETFLLDRTESTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLLTWLKGNTTGAASIRAGLPTSWT----------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3B0AEL5_9ACTN -------QLRQVVDASTANAGVTVRDLSGDQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQVSLDDEVLVTPAQVVDGTGELQHEEFPRVTLYRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPASRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TVVAFLTSG -PM---ASGDETVRQLARTVYDH- ->[subseq from] Beta-lactamase, putative n=1 Tax=Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) TaxID=32049 RepID=B1XL05_SYNP2 ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGN -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGDTSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] Peptidase S12 family protein n=1 Tax=Flavihumibacter petaseus NBRC 106054 TaxID=1220578 RepID=A0A0E9N4Z5_9BACT ------KSINAVLATHEATYGIAFKDIGSGQTF-YHNEKSSFHAASTMKTPVLIETYRQAK -AGKFSLTDSILVKNTSIVDGSPYSYQAIGKRLPINDILYRMITRSSNLATNMMIELV-GA -ENVMATMRSIGANDIRVLRGVEDDK-AFEKGLNNTTTAYDLMLIMEHIARGTAIDRQASQ -AMISILTDQYF-RDIIPARLPKEVKVASKTGSIN-GICHDSGIVFLPDGRRYVLILLSKG -IA-DLNTAKSVLAQVSEIIYKHy ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0B4_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGHNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B8TFF2_PSESP ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEDFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A656ZL01_BREPA --------VSELLEAAGGEWGVYLEDLQTNEKL-AINENERFYAASIIKVPIMTAVFAEAY -AGKLALEDKIKLRHEDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMMIDLV-GT -ESIRSAMRKTGMENSSFYNKLMVVPAELEG--YNEITAADIGSHLRYLATGKVISYDSCL -KMIAILKQQQH-RDRFPFLLPPKWEFANKTGSVTK-ITHDVGIFYTGPH---AISVSLLN -KGLAQKDAAAVMARIGSLLYDAy ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A6A7UHM5_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus muralis TaxID=264697 RepID=UPI00070F07FD --qTIEHDILALVEGFNGKIAYKIEN-GSGDTI-GLHKEESFQSASLIKIPMIIEGYRQSE -RKKINLKQSVTIPPSVVAGGSGVLHTLSNKVLTVEDLLTLMITVSDNTATNMMMSLL-GI -DEVNQCIKELGLKNTKLERRMQDFKA-LKEGRDNTISAEDTIICLKAIHTGDFLAKESQE -RIMRVFDNQQL-KDKLPSLMGGGVKIASKTGGIR-GVSHDCAIIRSEYQT-VYAAVLTEN -TR-SEEDSRQVISKIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium lianum TaxID=388280 RepID=UPI0009FF0972 -------------------VSLLIQD-EEGQTLfSQSADKRIPSASIIKIPILIALMEKVE -NREITLDARYSLQATDKVGGAGELQHLPDGSITFRYLAEEMIRISDNTATNILIRAI-EM -GYIQDWLKKNGYRDTQLNRLMMDFK-AIEEGRQNYTSPREINDILLNLWEGKWLKEDSRA -EIMHCLKGCAD-NSTIPSLLPAGTVVAHKTGTLDY-VRGDAGIILG--DKPLILSVFVEN -FE-SMEEAESAIGKIALKAFRDf ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0002D7A7D0 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ295 TaxID=2512146 RepID=A0A4Q7ZZC2_9ACTN -------------------AGVAVRDLSGDQQI-AVNGEFRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQYTFPQVVTLYRLAEYMIIYSDNTAANVLIDYLGGF -APVNALIDAMNQRETILARKMLDTEAA-RRGEENYTSPDDVISLLGAVWDADILAPPSRD -LMIGFMRRQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-VAVAFLTGG -PI---ATGDEVVRRLARTVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=uncultured Candidatus Melainabacteria bacterium TaxID=2682970 RepID=A0A650EKP0_9BACT ----LQRELMNLMEEYTVKPAVYVWDYETGNYI-DINASKSYATASIIKIPVLIDVFKSIE -AGQFSLNDTMPLTEYYRTEGSGSMQFKARNSYTIDKLAELMITESDNSATNMLMAKVGSM -TDVNQAIRSWGLKNTSVQTWLPDLTGT------NRTTARDMAQMLYNIDEDKFLTEESRA -RIFNYMGHVHN-NRLIQAGLGVGSVFLHKTGDIGT-MLGDAGIVIAPNGRKYIVVILANR -PHNS-VAGKDFIVHASEIIYNY- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R5XPW7_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Paramuribaculum intestinale TaxID=2094151 RepID=A0A2V1IUI6_9BACT ---AMTSRLKEFTTGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV -RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP -QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESAHE -TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGARNGINDAGYVFLPDGNGYSIAVFIAD -SAYDMAATEQLIAEISTIVFN-- ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-043 (Harlan) TaxID=2486463 RepID=A0A3N2L584_9BACT ---AMTSRLKEFTTGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV -RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP -QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESAHE -TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGARNGINDAGYVFLPDGNGYSIAVFIAD -SAYDMAATEQLIAEISTIVFN-- ->[subseq from] serine hydrolase n=1 Tax=Gracilimonas tropica TaxID=454600 RepID=UPI00035CBEE7 ---ELEQAIESRLSGLEGTFGIAFKNLNNPDEYvFINEDERFHAASTMKTPVIVELYKRAE -SGEFDVQDSIVVKNTSIVDGSEFTYEKLNAKTSLYDLAYQMITRSSNLATNILIDFL-GA -ESVTQTMRSIGADSIEVLRGVEDIK-AYEAGLSNTTTPRDLLVLFEEIEQGALLNDRSKE -AIISILKDQKY-NEMIPAKLPAEASVAHKTGWITN-VHHDSGIVYMPDGRAFVLIFLSKE -AP-NREAVLDAAADIASYCY--- ->[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A3D3IAB8_9BACT ---QLKEDINNELSKVEGEFGIAFKDLTTGETL-FINEKEVFHAASTMKTPVMIEVFKQAQ -AGHLSLADSILIKNDSIVDYSLNAYHQVGTMKPLSAIVYDMINMSSNLATNIVIELV-DA -KNVTLTMHDLGANDLLVLRGVEDSKA-FTAGLNNTTTAYDLMMIFEKLAKGKAVSPEADQ -QMIDILLDQKF-NEIIPAQLPANVKVAHKTGTIT-GVQHDSGIVMLPDGKEYVLVTLSKN -LT-DSEKGVAAMANVSELIYKH- ->[subseq from] Serine hydrolase n=2 Tax=filamentous cyanobacterium CCP3 TaxID=2107704 RepID=A0A2T2VXW7_9CYAN ----LKGELENLATLTPGTPVAFAVDLDSGQYV-DLGGAEPVAAASTIKVPILIAFLQQVD -AGTVALNQSLMLQEEHMAGGSGTLREAVGTEYTALEVATRMIVASDNTATNMMIAALGGI -EALNQTFAGWGLEHTVLRNPLPDLDGT------NTTSAKDMALIMALVDQGGLLTPRSRD -RLFSIMQRTEN-ISLIPSGISDTSLTAHKTGDIG-GLLGDVALVDVPNGKRYTLALLVQR -PTND-GRASELIRRMTETV---- ->[subseq from] serine hydrolase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000825E24D ---ALGAQIDRIDRDTPGELGVYVKRLNGGETY-SHGAERFWYLGSMTKVPIAVAVLQQVD -AGKLKLSDTVELQDADRIDVSRVVRERTGRRYTVDALLDRMLKDSDNTAANMLIRTV-GE -DTVQRAAQALGTQGFK-------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Xylophilus ampelinus TaxID=54067 RepID=UPI000825E24D ------------------------------------------------------------- -----------------------------------------------NTALVQVANAPLGP -GRVQAVQRALKLKNGDLQRTIDDAYDRYYRHDINAATLDAYGAMLEKLARGELLKPASLQ -RLYAAMKLGTFTNHRLQAGLPRSEPFIHKTGTQYK-RACHAGVLRPQDRADAVVVAVCAA -GMDEHKDVDAVFQQVGRAIAQ-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A415FEF9_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A210Y0E9_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus capsici TaxID=2115968 RepID=UPI000E202E16 -----EQRITTLIQESPYNVHLFIKNLTTNQLLiSHQLETSFSSASLIKVPILLALLSYIE -KNKLSLNSTLTISPTNWVDFSVISEQRLTQ-STFYDLLLWMIITSDNTATNVLIDVV-GM -EYLNDYFQHIGLQDTLLQRKMMDVER-LAKGIDNRTSARDMAHLYTRVYQQELLAPTYNK -LVINILSRQRI-HDSLKRYLVEDVRLAHKTGGLDT-VDHDVGIFYTNAV-DYSMGVFITN -VT-DNDQARQLIGRLSKVVYDQ- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum ATCC 10953 TaxID=393480 RepID=A5TRP4_FUSNP --tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILTELMKKIS -EDKFSLSDTIMMANFMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] serine hydrolase n=1 Tax=Proteiniborus ethanoligenes TaxID=415015 RepID=UPI000B82F269 -----IENINRYIEGAKGEVSLVLKDLTNDKWIyTLNGNKPVQSASTIKVLIMVEALNQVL -QGKYSLNQIIDIREEYKVKYSIITDMTLK-SYPYLDLIILMNIVSDNTATNILIDLL-GY -ENINEMARKLGLKNTVLRRKMEEFK-AIKEGRDNYTSAMDMGVIMESLYRNLILTPEMCS -LALDILKRQKY-KDVLLRLISEDVKIAHKTGGLRN-LSHDIGIFYLDSVD-YLLGVFVTE -AES-DVEAKEIIGKISKVVYNYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides fluxus YIT 12057 TaxID=763034 RepID=F3PNS1_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNNVSYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase 1 n=2 Tax=Planctomycetes bacterium Poly30 TaxID=2528018 RepID=A0A518EQL6_9BACT ------EAIAAATTRSDGEVFVAYRDLGDGASW-DVRGDTVVHAASTMKVPVMVALHRRAF -EGRFDLEAPMNVHNSSIVDGSPYTYDRVGESLPASELCRRMIVRSSNLATNLLVDEL-GA -DQIQRTIEGLGVRHMRVLRGVEDGK-AYRAGLSNTATASDLRELLTAIAEGVAVSPEHSD -AMLETLAAQEF-SELIPAGLPEGIRVAHKTGSIT-GILHDAAIVMPEGVPPYVLVILTRD -FA-DSKDAADAIREVTRRV---- ->[subseq from] serine hydrolase n=1 Tax=Rhizobium meliloti TaxID=382 RepID=UPI0012963AE1 --hALEARLAELERRHGGRVGVAALNLSTGARV-GHRADERFLMCSTFKALASAMVLARVE -----KLDRRIVFSKEVLVYFSPVTETRVGGEMSVAELCMATLTQSDNTAVNLLLESFGGP -PALTEFVRSFGDELTRLDRFEPELNEDGPDDLRDTTTPGA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus simplex NBRC 15720 = DSM 1321 TaxID=1349754 RepID=A0A223EE15_9BACI --qTIEHDILALIEAFNGKIAYKIEN-GLGDTI-GYHENESFQSASLIKIPMIIEGYRQSE -QKKIYLNQPVTIPPNEVTGGSGVLHVLSNKVLTVEDLLTLMITVSDNTSTNMMMNLL-GF -EEINQCIKELGLKNTVLERKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGNFLMKESQE -RILRVFDNQQL-RDKLPSLMGRGVKIASKTGGIR-GVAHDCAIIRSETQT-VYAAVLTED -IK-SEEESRQVISKIGKLIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:1320 TaxID=1262922 RepID=R6ETJ0_9BACT ----LTDSLSRIASACPGEMGVAVI-VNDTETI-TVNNQSVYPMMSVFKVHQALALCDDFD -KRGLSLDTLIRINRSELDPWSPMMKDHPERILTIRDLLRYTLTQSDNNASNLLFKRLVDV -AKTDSFVATIPRPSFRIVYTEEEMAVDHDRAYSNYTSPLGAAMLMNRLFTDKLVSDGKQD -FIKNTLKECETGTDRIVAPLEPDAVIAHKTGSGYNGAHNDVAYICLPNNISYALAVFVKD -FKGNEAQASRYIARASAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Ureibacillus thermosphaericus TaxID=51173 RepID=UPI000BBC6272 ------EQIRTLLDEADCKVHLVVKDLKTDQYLiAEKMDEVFPSASIIKVPILLAVLHYVQ -ENQFSLTDVVEISPENKVDFSVITEQDLT-SCTIYELLLWMIITSDNSATNELIDLL-GF -EKLNHYFKKIGLAHTNLERKMMDFEK-INLGYDNVTTARDMAHLFSLIYQQQLLIDEFNK -IAIDILCKQRD-YERLKRYIA-DVRIAHKTGSLDT-VCHDAGIVYHPTMD-YLIGVFLTE -LN-DFEFGKRFIGRISKIVYDYf ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI001290E54C ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADPDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus locisalis TaxID=305507 RepID=A0A1I7DBX9_9BACT ---TLQEQLQSKLDSIQGDVAVAFFNLSDPSDSlLINADEEFHAASTMKVPVMIELYKQQE -AGNLDLNDSILLKNESIVDGSPYSYSKIGTTVALKDLMFPMITVSSNLATNVLIELV-GA -KNVTATMRDLGASKIEVLRGVEDQK-AYDLGLSNSTTAKDLMIIMAAIAQNKAGTKKDCD -EMIQIMKDQQF-NEIIPFYLPEDVAVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LE-DFDKGTEQLAGISKTVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2U8SQD7_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma spitsbergense TaxID=431554 RepID=UPI0012F8599E ------------------RVSLSTRSLVDATLSfAYRADVRVPSASVIKLPIMLELMERVK -AGMFNLDAMHTLTEAEKVGGDGVLQTYADQSVSYRELLRLMLIKSDNTATNIIIHLL-GR -DAINQRLRKSGLERSQLNRVMMDTLAA-KQGRENYVTAQEMNALLEKVYRHQVATPEGCE -AMLTILKQNED-VLTIPRLLPKSVVIAHKTGTLAY-VRGDAGIVYAE--KPFLLAVFVEG -VP--TPEAERIIGEVVLICYTYf ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T028_9BACT --tALQNELTDFVKDKDARIGMAVI-IDGKDTV-AVNGKEDFPMLSVYKLPIALALADNYR -VKGLDFSEPIAIAKEDLHLYSPMTGRLLASSMPTREILNYMLHQSDNNASDLAVKKLGGT -ENVMKWLSKSGLSGVKVVSTENEMHINPELSYKNSSTPIAMARLLDKLDTE--WNDSLSK -EIKQMMETCKTGENRLAKLLPTNAVTGHKTGTGFIMAVNDVGYVHLSNGHRYSIAVFIAD -AHYDMAESENIIAQISEMVWR-- ->[subseq from] Serine hydrolase (Fragment) n=2 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=A0A353JXU4_9CLOT ----LKKEIKAFIKTQSGNIAVSFYDLNEKSGF-SIDGEKRMLSASTIKLVIMAELMRRVH -IGEISLENKITVTVQMKTGGDGILKELEPGHFTIKELLTLMIIISDNEATNILIDFL-GM -ESINQMAQAMRLKQAHLGRKMMDSEA-KKAGHDNYICAEDIRDILKSIYEGTCIDGKSSK -MMLNILKHQQQ-SGRLQLYLPEEVEVAHKCGDLDC-LENDGGIFFLPKH-PYILVVLTNE -MP-TNKDGREAIGKISWIVYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudohongiella sp. TaxID=1979412 RepID=A0A2D9DQ34_9GAMM --------VAAASNNIRMSIGVAGLAGVNDDAMvLLGSSESYPPASTIKMLLIATLMHQVD -AGMLSLDDTTTVEQSDIVGYGEIQNELVPNEVTLRRLAQLTVTVSDNTATNVLVDVV-GY -DAMQALADTLELQDMQFGRKMFE--AATPPAKENYITAADSIKLLKAIYDGEFLSESSRQ -TVIDWMSAQTV-KTKIGAGIPADVPIAHKTGENAS-VTHDLGYILWPGN-EVALAIFAQS -EETDQATVNPVVAEVAGIIYEH- ->[subseq from] Serine hydrolase n=1 Tax=Verticiella sediminum TaxID=1247510 RepID=A0A556AE82_9BURK ------------------------------------------------------------- ---------------------------------------------------------I-GP -ARVRAVRDALDVGEDALAATMPEAYARYYATQRNMAPLDAYGAMLERLVAGDLLSDESRA -RLFAYMKLDEDGDYRLEGGLPQGIPFIHKTGTQFE-QACHVGVAYPESGKRAVVVAACAS -GLDEAKEAGAVLRRIGRAVAD-- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus TaxID=1279 RepID=UPI0003C5E01E ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMAYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5WYP9_9BACT --kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK -DNVNAMLHSLGLPKTLLRRKMMDIAA-VRRGHENIATPQEMVRLLEAIFKEKALDKQATA -EFIKQLSTLKQ--SYLPRYVPESVQVANKPGELE-GVRNDSGIVFAQNQ-PFAISVMTAY -DR-DEKAAERAIGEVALEAYRYf ->[subseq from] serine hydrolase n=1 Tax=Leptolyngbyaceae cyanobacterium CCMR0081 TaxID=2292702 RepID=UPI0013D14FE7 ----LKTKLEELQELIELTPTIYVFDLDTGNYV-EVAGNAETPAASTIKLPILIAFFKAVD -EGRITVDQALAMQSNQIAGGSGDMQGQPPGTYTALEVATQMIINSDNTATNMMIDLLGGP -QVLNQQFADWGLTMTILRNPLPDIEGT------NTTSAQDLVRMIAHLHKGDILSLRSRD -RVMNILQRTYN-KKLLPAGVSETTISYNKTGNIGE-VLGDVALMDLANGKRYAIAALVRR -PEND-GRAQELIRRISQAVYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Proteiniborus ethanoligenes TaxID=415015 RepID=A0A1H3MQ78_9FIRM ------ENINRYIEGAKGEVSLVLKDLTNDKWIyTLNGNKPVQSASTIKVLIMVEALNQVL -QGKYSLNQIIDIREEYKVKYSIITDMTLK-SYPYLDLIILMNIVSDNTATNILIDLL-GY -ENINEMARKLGLKNTVLRRKMEEFK-AIKEGRDNYTSAMDMGVIMESLYRNLILTPEMCS -LALDILKRQKY-KDVLLRLISEDVKIAHKTGGLRN-LSHDIGIFYLDSVD-YLLGVFVTE -AES-DVEAKEIIGKISKVVYNYf ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-110 (HZI) TaxID=2486473 RepID=A0A3N2NKN5_9BACT --aDLQRELQEYVSDKEARIGIGVI-VDGRDTV-EVNGHQRFPMMSVYKFPISLALADVCR -ADGMTFDDSCTVVASELHRYSPMTDSYADIDISIRELLAYTLQMSDNNASDILLKRAGGA -GRVDSYVRSLGVGDIDIRWSEAEMHADTARCRDNSCTPLAMAALLSRFDAAD--DDALTA -EIKRLMETCATGTDRLLPPLEAGALLGHKTGTGDLQAINDVGYVHTPEGHVYSIAVFISD -SSLDMQSTSAMIAEISRMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus composti TaxID=720633 RepID=A0A3N9UAK6_9BACI -----KQIIRQMIQDVPYNVHLFVKEAKENQFLiGEQLDAVFSSASLIKVPILLAVLDHLE -RTNQSLDHRLEITPENVVEFSVLTEQKVT-TCTIYELLVWMIITSDNSATNVLIDYI-GM -EGLNHYFSNFGLTQTKLQRKMMDFKR-LEQGFDNVTTARDMAHVFTSLYRQTLLSQHNNT -IAIDILSRQRI-YEGLKRYLVGDVKIAHKTGGLET-VDHDVGIIYTETVD-YIIGVFVTE -VSN-NDEARQLIGRISKVVYNEf ->[subseq from] Beta-lactamase class A n=1 Tax=Lysinibacillus sp. SG45 TaxID=1500271 RepID=A0A1H8BYX2_9BACI -----ENQIQDLIQKTPYKVHLFVKDPKTEQFLfSHQLEESFSSASIIKVPILLAVLAYTG -KHNISLHSALTITPTDWVDFSVISEQCLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -DFLNDYFRQIGLQETLLQRKMMDVER-LAMGNDNFTSARDMAHLFTRIYQKDLLASPYNE -LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYGSSFD-YLIGIFITN -VT-DNDLARQLIGRLSKVVYDH- ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus lasiicapitis TaxID=1636719 RepID=A0A544STV0_9BACI ----LVNKIRSLTEQSAGTWGIVLEDLDRGAKW-ISNGDELFYAASVIKVPIMVAVFSAVE -RGEISLTDELILKEDDFVGGSGVLQHLTPGTLSICDIVMLMIIQSDNTATNILIDLV-GV -EHIVQTMKEAGMEKSTFYNKLMMNNPR-PK-GYNQITANDIGKLLKLMATGKLASEEASK -QMIAIMKKQQI-KDCLPEKLPSPWELAHKTGWIP-GTRHDVGIFYVGQRK-LLATVLSKE -ED--DLLSKQILAEIGEEIYNY- ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium Isolate-004 (NCI) TaxID=2489216 RepID=A0A4Q0IAF6_9BACT ----MTSLLKDFAAGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV -RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP -QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESAHE -TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGDRNGINDAGYVFLPDGSGYSIAVFIAD -SAYDMAATEQLIAEISTIVFN-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium RIFCSPLOWO2_01_FULL_60_11 TaxID=1797947 RepID=A0A1F9UFG0_9BACT --qELEQSINYQIRHFPGQTAVYIRDLNTGWTI-EHNTDVLFPSASLVKLPIMAVLYQAQV -SGRLSLDESLPLLRKLKASGSGHLRFRRTGSIRVRELIYKMITESDNTATNMLTDRL-DL -DYINRHFLALGLNRTNFSRMIMDLRRR-DQGIENYTTAQDMGNLLEMIYFKNLT---GSE -EMLETLKNSKI-NDRLAMGIPSNWQIGHKTGLMNN-ACHDVGIVFSPTHD-YVICVLTTK -AR-RFRRAKGFISEVSHLAAMYy ->[subseq from] serine hydrolase n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=UPI000B89590C ------------------------------------------------------------- -----------------------------------------------------------GP -RRVQALARALGMPESQLQRTMDEAYARFYRRGDNTAPLVDYGAMLERLVRGQLVNAQHQQ -QLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQFQ-RACHMGVIDPQDGRRAIIVATCAE -GLDEQKQAGRAFEALGRAITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:967 TaxID=1262849 RepID=R5KEM9_9CLOT ----LENQLKNLSAMYSIHPSIYVWDYDTGNYA-DVNADEVFPTASIIKLPVLVQLFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYTIDTLARMMITESDNSATNMIMARLGSM -TDINQGLREWGLKHTYVQTWLPDLGGT------NHSTARDMATILYNIDNPQFLSTSSRE -KIFDYMGHVHN-NRLIAAGLPAGAEFLHKTGDIGK-MLGDAGIVFAPNGKKYIVVIFANR -PHN-SPLGKEFIVKASETIYNY- ->[subseq from] Beta-lactamase n=48 Tax=Bacteroidetes TaxID=976 RepID=L1PB72_9FLAO ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. PCC 7117 TaxID=195498 RepID=A0A1B1U2B5_9SYNE ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGD -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. NBS58-1 TaxID=2595005 RepID=A0A5B6TW90_9BACT --------VLAELGKQKGTFAVAFKDLKTGEEL-LINEHESFHAASTMKTPVLIEAYKQAA -EGRFSITDSILVKNESIVDGSPFSYTQLGQKRPLAELLYKMIIQSSNLATNIVIEQL-DA -KKVTQTMRELGARDLQVLRGVEDTK-AYRQGLNNTTTAYDLMVLFQLMAQGKTVSPAASK -EMIKVLLDQKF-KDVIPAKLPQEVKVAHKTGWIT-GVRHDSGIVFLPDGRQYVLVLLSKG -LV-DEKAGIQAMANVSEMIYRH- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A5Q5G016_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGCNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A5N7TM30_PSESP ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus vaginalis TaxID=1756987 RepID=UPI000A26AF15 ----LQNKIENIVEESSANISVSFYDLDLEEGF-STDGDKQVPSASMIKLLILLKAFYECD -KGKLNLEDIISLDDYERVEGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR -DEINKIGHELGLEKTILQRKMMDSLAK-EKGLDNFTSSNEILKILKMIYEKDFINEDYSQ -LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ -AE-SNVLAKEIIGEISLKIYN-- ->[subseq from] Beta-lactamase n=1 Tax=Acidovorax citrulli (strain AAC00-1) TaxID=397945 RepID=A1TIK6_ACIAC ------------------------------------------------------------- -----------------------------------------------------------GS -QRVQALARTLQVQKDDLKKTMEEAYDRYYAWGTNTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAQAIVVATCAE -DMDEMRQAGRLFEQLGRAITR-- ->[subseq from] Serine hydrolase n=1 Tax=Cystobacter fuscus TaxID=43 RepID=A0A250J7M9_9DELT ----LREALQERISQVGASVAVAYQRLGSPDSL-YLEADRSFHAASTMKVPVMLEVFRQVD -AGTLSLEEPVTLTRQSIVDGSPYEHERLGQPVPLRELVERMITRSSNLATNLVLSRV-DA -RRVTKTLRALGARRMTVLRGVEDGKA-HARGLNNTATARDLASLLSALEQGRAATPASTR -AMRSILLAQEL-NREIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPPGHPAYVLVVLTRG -IP-DEAVARSLIVELSRQVYAH- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella denticola TaxID=28129 RepID=Q8KT57_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRITAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium marinum (strain ATCC 25205 / DSM 745) TaxID=880070 RepID=G0IZA1_CYCMS ---QLEEEIRKLMNETEGDFALAFRSVDGEESElFFNEKETFHAASTMKTPVMVALFEQEA -AGKFSLQDSILIRNSSILDGSTYQYKRIGENATLYELMYEMIVRSSNLATNILIEKV-GA -KNVTQLMRELGAEDIQVLRGVEDLK-AYEAGLSNTTTALDMMLIMEAIAKHKV---AGSK -KMIDILSDQHF-NDLIPKYLPKEVKIAHKTGAIT-GVQHDAAIVELPDGNRYVLVILSKN -LT-DEKAGKECIAKISQMIYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A2E0KYR2_9CHLR ---TLQSDIQTIIDESGIQAGVSVWHIERDEQT-DVNGDQPFPMASVFKIPILATAGKQLK -EGRISLDTRIELKDADKSAGSGILPYFEAGLPTVRDLLTLMIIISDNTATDMTVELLGGA -QVVESYMHEIGLGDIYFKMNCKDLLKFSTGPDNNVSTANAMTQLVHMIFQSEIVDGAIRD -ELLNILLKQQF-NVRLSRFLPPNVAFAHKTGTIG-GIRNDSGVIYINDDSHVIVTLFVWW -DDQRIFEVETAMGKIGKLVYDHy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8R6C6_9BACT ---ALEGKVRGLIATSGATVAVAFQDLQTGREL-LINPGVSFHAASTMKVPVMLEIYRQAQ -FGKLSLDERLPVKNESIADGSTFSYKKIGGTETVRELLRLMITESSNLATDILIERV-TP -ARVMELMRRMGARDMRVLRGVEDGK-AFERGLNNTTTARDLLVLMRAIAEERAVSIIASR -EMARVLLDQKF-NEGIPAGLPPLIPVAHKTGSITK-IEHDAGIVFLSGRKPYVLVVLVRG -IAE-EARAHKLIADISRAIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9IHN4_9BACT -haKLEAEINRVADQLNGVLGYAIKDLSTGESF-YRNADLVFPTASSIKLAVLLELMRQDQ -EGTLSLNEKHTVRHSELPPTDPILHMLGDGTMTLRDVATFMVVLSDNGATNILIDRA-GM -DNINAEIARLGLAQTHLRRRMIDIEAARRG-DENVSTPRELMVLLERVRGGGALDAAHTK -EYSDLLGLPK--DSLFNKALPSTVRIEDKPGALD-AVRSDAGIIEVPGH-PFAMSIMTTY -LG-SNDEGERAIKQIARLAYEHf ->[subseq from] serine hydrolase n=1 Tax=Olivibacter sp. XZL3 TaxID=1735116 RepID=UPI001066BF7D ----LTKKINEILQGAQGTFAIAFKDLSDNDTY-FYNEHEVFHAASTMKTPVLAEAFRQME -QGKFSLTDSVEVYNKSIYDGSPYSYALLGTKVTIADLLHRMITQSSNLATNIVIDLV-GA -KNVMKTMRQLGAKEMKILRGVEDSKA-FAHGMNNTVSAHDLLLLFEQLAKDSMVSKQASE -EMVAILMQQHF-RGTIPAKLPGTVKVANKTGSIDK-VFHDSGIVFLPDGRRYVLILLSKG -LEE--KRAQESLAEVSSVFYHY- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R5WK83_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Virgibacillus phasianinus TaxID=2017483 RepID=A0A220U3D5_9BACI --kQLIDKIKTITKEAGGTWGISLEDLDTKETW-TSNGEQVFTAASVIKVPILIAAFAAFD -QKLLVPSDTVELKKEDLVAGSGVLQHMTPGTFTIYDLLTLMIIQSDNTATNMIIDLL-GA -EKINQTMEELGLKKSKFFNRLMIVPAN--REGVNQITALEMTAMLKQLVTGQVVSLYACE -QMIDIMKKQQL-QDCLPGRLPEAWQLAHKTGSVTR-VCHDVGIFYVGEK-TMIASVLSKG -ID--DIKAPGLFADIGFEIY--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus gelatini TaxID=1655277 RepID=A0A3M8B2V4_9BACL --------VSELLEAAGGEWGIYLEDLQTNEKL-AVNENQRFYAASVIKVPIMAAVFAEVF -SGKLALEDKIRLRREDLVGGAGVLQHMTPGTFTVYDLVTLMIIQSDNTATNMLIDLV-GT -DSIRSIMQKTGMENSSFYNKLMIVPAELEG--YNEITAADIGSHLRYLATGKIISYDSCL -KMIAILKQQQH-RDRFPFLLPPKWEYANKTGSVTK-ITHDVGIFYTGPH---AISISLLN -KGLEQKDAASVMARIGRLLYDLy ->[subseq from] Serine hydrolase n=2 Tax=Pseudomonadales TaxID=72274 RepID=A0A3R9BWX5_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A0A3S4PGW0_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI00048C361B -------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE -EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV -DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE -QMVNLLTRCQ-GPVSIAKNLTKEVIVAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Burkholderiales bacterium TaxID=1891238 RepID=A0A4Q3UQC8_9BURK ------NAVQRLGTTFQGRIGISIREIDAGWTV-AFGGDASLPQQSVSKLWVGIATMQQIE -RGRLSLSDPILVHRSDLTVHQPLRPLVTANGTTVGSLLELAMTRSDNSANDILLWKIGGP -PIVRDMLSRDGVLGVGFGPGERDLQARYLAAPYDGASANGVTLGLALLAQGKLLKPSSST -HLLALMRASKTGPLRLRSGLRPGWTLAHKTGTGQATGYNDVGILVSPAGHRYAVAVMIAS -THQPIPARMRLMGDVTRAIIR-- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3R472_9BURK ---RLRTQIERLDADTPGDLGVYVKRLDNGEAY-GHGADRRWYLASTVKVLIAIAVLQQVD -AGRLKLDAQVALQDSDRIDVGKLVWEKTGTRHRVDALVQRMLRDSDNTAANMLIRTLGGE -VPLNDSAAAAIDAELHPDARKLSNAQRYYRHQNNSATLEGYGAMLEKLVRGELLKPASLQ -RLNDGMKLGIYTNYRLQAGLPRGVDFIHKTGTQHQ-RACHAGVIRPQNQAQGVVVVACTA -ELDEQKAAGPVLQRVGQAVTQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus acidophilus TaxID=53633 RepID=A0A2T2WFD7_9FIRM ----LRMTLESLVAQLPGQYGIFARNLNTGQTI-AMGEHQVFPSASLIKVPILAEVLRRVE -EEGLSLDETLVMRAEDQVPGSGVLKDLTPGTYTLRDLSMLMITVSDNTATNLLIDYL-TV -DSVNALLRRLGLPQTSLERRLERVPAQ--VTRVNRTTAHEMARLMELVATGQLISQDVSR -RMIDRLQRCQAEDPRYIGQLP-AIQVAHKTGSLAQ-ARHDCGIVFHAKG-VFVASILSQG -APA--SQLQDRIHRIGQFIF--- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax avenae subsp. avenae TaxID=80870 RepID=A0A2R4EBK0_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQVLARSLHVRKDELQKTMEEAYDRYYARGANTATLAGYGGMLEKLVRGQLLTPPHQQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQYH-RACHMGVIDPQDGAHAIVVATCAE -GMDEMRQAGRLFEQIGRAITR-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. PCC 7117 TaxID=195498 RepID=UPI0009FEA9ED ------TTQAAIAADSTLDASLLFVDLDTGEYL-DVAGDRPLSAASTIKIPILVAFFEAVD -SGKVNLDDSLTLTQEVIGGGSGGMQKTPGSTYTALYTATEMSVNSDNTATNMITELLGGD -AVLNAKFQQWGMTQTQLNNPLPDLEGT------NLTSAKDLAHLLARVNQGEILSVRSRD -RLFRIMGATSN-DRLLPQSLGQGADIVHKTGDIGS-IIGDAGIVDLPNGKRYVAAIFVER -PYND-PKGKELLHKISRQFYDH- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7R7T1_9BACT ---SLRSQVEARIARAPARVGVYYRDLATGDSL-TVGSGVRFHAASTMKIPVMIQLYRDRD -AGVLSLDDSITITNTSIADSSPYLYKRLGQRASIRELIELMETVSSNLATNLLIAKV-NA -TRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIANGTAASAASCR -EMLAILGRQQF-NEGIPAGLPPGTQVYHKTGWIGQVVYHDAALVEPAGRGRYVLVVLTGG -IQKD-ADSHALVRDISRLVFD-- ->[subseq from] serine hydrolase n=1 Tax=Ureibacillus thermosphaericus TaxID=51173 RepID=UPI00030D8C5C ------EQIRTLLDEADCKVHLVVKDLKTDQYLiAEKMDEVFPSASIIKVPILLAVLHYVQ -ENQFSLTDVVEISPENKVDFSVITEQDLT-SCTIYELLLWMIITSDNSATNELIDLL-GF -EKLNHYFKKIGLAHTNLERKMMDFEK-INLGYDNVTTARDMAHLFSLIYQQQLLIDEFNK -IAIDILCKQRD-YERLKRYIA-DVRIAHKTGSLDT-VCHDAGIVYHPTMD-YFIGVFLTE -LN-DFEFGKRFIGRISKIVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R6GVA8_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADQDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGYNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Cyclobacteriaceae bacterium TaxID=2099675 RepID=A0A5C7Z8I3_9BACT --eETSRQIETILSKPKGSFAVAYKDLLTGEEI-LINEHALFHAASTMKTPVMAEVYRQVA -EGKFSLKDSVLIKNDSILDGSSFSYDHIGEKRTVYSLMYDMIIISSNLATNLIVELV-DA -KNVTQTMRSIGANDIQVLRGVEDTK-AYEAGMNNQVTAYDLMLLFEKIDKEEIVNAEASM -AMMDILLDQKF-NDIIPAKLPAEVKVAHKTGSIT-GVRHDSGIVFLPDGKKYVLVLLSKD -LE-DEDAGVQAMAEVSEVLYQY- ->[subseq from] Beta-lactamase n=2 Tax=Prevotella TaxID=838 RepID=A0A096CAA3_9BACT -----TDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9DS78_9CHLR ------SEIKSLVSEINGEVGVAALNLKNDKNI-YINENESFFMASVFKIPLLITLYKQVD -LGNIDMDQRITLAQDLKTGGSGVLRELTPGIPTLFDLAMLMIIISDNTATDILFNML-GK -DKINSLMRQNNLSKTFTPMSCQDLLSALNEDKSNVSTAYEMVTLMKLLTTGKILSESSTN -SVLSILKSQKL-KTIIPHYIPKNIKIANKTGGVYS-VRSDVGTVWSPKG-PYTIALMAKN -VT-NEPDIDTKLAKISLSIYEY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. B14905 TaxID=388400 RepID=UPI0000F3867E -----ENQIQDLIQKTPYKVHLFVKDPKTDQFLfSHQLEESFSSASIIKVPILLAVLAYTG -KHNISLHSALTITPTDWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -GFLNDYFRQIGLQETSLQRKMMDVER-LAMGIDNFTSAQDMAHLFTRIYQKDLLASPYNE -LVIDILSRQRV-YEGLKRYLVDDVKLAHKTGGFDT-VDHDVGIVYGSSFD-YLIGIFITN -VT-DNDLARQLIGRLSKVVYDH- ->[subseq from] serine hydrolase n=1 Tax=Salinimicrobium terrae TaxID=470866 RepID=UPI000409E3B5 --qKTEKKLQEIFQSSPAITGLVAVDLTSGEKI-SWNPDVQFPQASSIKIPILIEVFKQAS -EGKYSLSDRLPVNSTNLVGGTGILKNLDDPALSIKNLGILMIALSDNSATNSLIDLV-GI -PKVNKTLQSLGMKQTLLQREMMNSTA-SARGEENLATPAEAAKILQLLYKGEFINPNVSK -EIVDILKMTDREDSRLAAGIAENVDIAFKPGFIN-GVSVEWAIVNLQQR-PYAVAIMESH -KV--SGEAEEVMEDVSKILYNYf ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534B4Z7_9GAMM -------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFAYRAGG-GRTLRELSELMITVSSNLAANLLMDRL-GV -ENIRAGVHALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR -QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDIAR-IWHDAGIVLAS--QPFVLVVLTRG -LEN-PKESTALIAGITRELYR-- ->[subseq from] Beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=G5SM21_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGSNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A4P8LYC8_BACFG ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGSNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=2 Tax=Pseudoxanthomonas wuyuanensis TaxID=1073196 RepID=A0A286CYM8_9GAMM ---ALQARLQAVEKRFSGRIGVYLHHLGRNESL-SYHADEPWYLASGVKVPVAIAVLREVE -QGRLALDTRVRLQESDFVDGAGQTNSYPAGTLRVSFLLEQMIIHSDNTASDALIRTV-GL -DQVNSVATELLATNKLIVTSLSDVRRAYYATEVNTAPLSDFGRMLATLSDGLALNPEGTA -YLLNLMSRVKTGEQRIKARLPVASRFAHKTGTQHR-RVCDLGIVATPRQERVVIAACARG -GT--QAAGERALREIAAAVT--- ->[subseq from] Serine hydrolase n=2 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3C1MKT8_PSESP ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000D205452 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Candidatus Omnitrophica bacterium ADurb.Bin205 TaxID=1852852 RepID=A0A1V5X8F6_9BACT -----TAQLMREIDKFKGDSAVIIKDLESGWEF-VYQKDKLYPSASLAKIPIMAAAFIAAG -KGKVNLDTEIALKPSDKLTGSGVLKSLPAGTFNFERLIGFMIYDSDNTATNIVTKTL-GI -DYLNNTFKELGLKHTKLLRRVADYRLR-NQGVENYTTAEDMAFLLEKIYLRSLFNKQVSD -KCIGLLKLTRM-NDRIPRYLPADITIAHKTGLERN-VCHDVGLVLTPKGN-FLICVLTNY -KNTDLKTAKQFIARIALLTYKFy ->[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A3D6ERG4_9BACT --eETSQQLETILSKPKGTFAVAYKDLTTGEEI-LINEHLLFHAASTMKTPVMAEVYRQVA -EGKFSLKDSILIKNESILDGSTFSYDHIGEKRTVYSLMYDMIIISSNLATNLIVELV-DA -KNVTQTMRNMGANDIQVLRGVEDTK-AYEAGMNNQVTAYDLMLLFEKIDKEEIVNAEASM -AMMDILLDQKF-NDIIPAKLPADVKVAHKTGSIT-AVRHDSGIVFLPDGKKYVLVLLSKD -LE-DEQGGVQAMAEVSEVLYQY- ->[subseq from] CepA family class A extended-spectrum beta-lactamase n=6 Tax=Bacteroidales TaxID=171549 RepID=A0A679HPI5_BACT4 ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides dorei TaxID=357276 RepID=A0A4R4GF13_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus harei TaxID=54005 RepID=A0A133PS82_9FIRM ---GLQNKIENIVEESSANISVSFYDLDLGEGF-SINGDKQVPSASMIKLLILLKSFDECH -EGKLNLEDTISLDDYERIDGSGILKELYRNHFSIRELLTLMIIVSDNTATNILIDLL-GR -EEINKIGHEFGLEKTILQRKMMDSLAK-ERGLDNFTSSNEILKLLKMIYVKNFVNEDYSE -LALDILLRQQE-RDRLQRFLPEDLKIANKSGDLDN-LENDGGIFFTKNK-NYILVVLVNQ -AE-SNVLAKEIIGEISLKIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus glaciei TaxID=2283160 RepID=A0A5J6SSG8_9BACI ---TLVNSILELIEQSDGTWGIVLEDLDLGEKW-VWNGDELFYAASVIKVPIMAAVFAAAE -MGKLAISDQLVLKSEDFVLGSGILQHLTPGTFSLKDIIMLMIIQSDNTATNIMIDLV-GM -DNIVQTLKKAGMEKSTFYNKLMMNNPNPK--GFNQITPNDISKLLKQMTTGELVSPEASE -QMIGIMKKQQI-KDCLPDKLPTAWELAHKTGWIP-GTRHDVGIFYVGQRK-LIATVLSKD -VD--DLLSKQILTEIGGKIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Thermomicrobiales bacterium TaxID=2482790 RepID=A0A5C7JKA3_9CHLR ---AFAEAMADYVDDLSGEIGVAVRDLETGDTF-GYNATEIFPTASTLKVPLIYVLYRLAD -AGAIDLNERVTLSYANRVPGSGVLQHMDEGLPTLRDLAELMIIVSDNWATDLLWNRL-TK -PVVDSTLAEIGLTQTSLPFTIHEIFAMVYDARNDTSSPADMVRLLTLIDAGDGLSDVSRD -AVLDTLKHQNF-TTILQGRLPEGIEVAHKTGSLR-GVKNDVGLVSAPNA-RYAIALMSRG -QD-DIPEVTDRLSRISRWVYD-- ->[subseq from] Beta-lactamase n=2 Tax=Pseudomonas TaxID=286 RepID=A4VI24_PSEU5 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDHLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase n=4 Tax=Pseudomonas TaxID=286 RepID=S6JUA9_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri (strain ATCC 17588 / DSM 5190 / CCUG 11256 / JCM 5965 / LMG 11199 / NCIMB 11358 / Stanier 221) TaxID=96563 RepID=F8GZ31_PSEUT ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Cystobacter ferrugineus TaxID=83449 RepID=A0A1L9BKP4_9DELT ----------RISQVKGATVAVAYQRLGSPDSL-YLEADRSFHAASTMKLPVMLEVFRQID -AGTLSLEEPVTLTHQSIVDGSPYVHERLGQPVPLRELVERMITRSSNLATNLVLSRV-DA -RRVTKTLRALGARRMTVLRGVEDAKA-HARGLNNTATARDLASLLSALERGRAASPASTR -AMRSILLAQEL-NREIPAGVPPGTPVAHKTGQIS-GVLHDAAIVYPPGHPAYVLVVLTSG -IP-DEAVARSLIVELSRQVYAH- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. HSS6-12 TaxID=2720024 RepID=UPI00143C0B86 -------QLAAIVDDAAATAGVTVRDLSGDQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQVSLGDGVLVTPADVVDGTGELQHETFPQVTLHRLAEYMIIYSDNTAANVLIDYLGGF -APVNALIDSMNQRETILARKMLDTEAA-RRGEENYTSPDDVVSLLGAVWDADILAPPTRD -LMINFMRRQTL-NNKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-VAVAFLTGG -PI---ATGDEVVRRLARTVYDY- ->[subseq from] Class A beta-lactamase n=1 Tax=Fusobacterium sp. CM22 TaxID=936563 RepID=X8GUG7_9FUSO --tEWKKEIEKIISQVEGKVCVNFYDLNRIDGF-SINGNEKVLSASMIKLLILAELLKKAS -ENKFSLSDTITITNFMKTEGDGVLKENIGHHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYFPSDIKIAHKCGDLDN-LENDGGIIWIGDR-IYILVVLTSG -MS--NLQCKQTIGKISKFIYDK- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7B5C82 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAITRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2G6HSG1_9BACT --kDLDRQIKEILAGQPGVYSVSYRDLASGREW-HFNADDCMHAASTMKVPVMLRVFQKLE -RENKSLNDALRVHNSSIVDGSAFAYQFLGKNVPIEHLVRLMIIRSSNLATNILIDWV-DA -KKVTELMVELGARQTSVLRGVQDLK-AFEKDMNNTTTSRDMLQILISCYQSELFTKTSRD -AMIQFLLDQEF-NDLIPAGIPANAKVAHKTGSISR-VHHDAALVMLPDGSSYGLVVFSRD -FGEERERVKQTIRNISSAVYQY- ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. 17J42-9 TaxID=2492393 RepID=A0A4Q5M1D2_9BACT ------------------KVSMSVEGMSGEEFF-SYRPTVIVPSASVIKIPILMELMEKVK -AKQIDLNKVYILQASDKTGGSGVIANMPDGKFTIRELAQEMIRSSDNTATNILIREV-GM -EAVNQNLMRLGSTQTRLNRIMMDTMA-VKQGRENYVNTLEINDLLRKIYKKEVATPALCE -EMIEILKNCGD-TTTIPRNLPKDVVIAHKTGGLAY-VRGDAAIVYTK--EPFIISIFIEG -FKE-ESTAERIIGDLAEICWE-- ->[subseq from] Serine hydrolase n=1 Tax=Luteitalea sp. TaxID=2004800 RepID=A0A6A7L9E8_9BACT ----VADRIAALTKGFKGTVVFYAKNLNTGREL-ASDPDARVRTASTIKLPVLCALESLVT -NGKVKWDERLVLKPEEKVSGSGVLQSLAEGTLTVRNLAILMIIVSDNTATNLLIDRI-GA -DTVNDYLDTLGLTKTRLNRKIVSGDSENKRFGLGVSTPRQMVTLLERLHQGKIVSPAASN -DVIDILKKQQI-TAASGRHAPQQWTVASKSGSLN-ALRSDVGIIYTDAD-PIALAITVED -MPETDNVGEKLIWQLTEAL---- ->[subseq from] Beta-lactamase class A n=2 Tax=Pontibacter mucosus TaxID=1649266 RepID=A0A2T5YFS3_9BACT --qQTEQQLAAIINRSPAVTGLVAVDLTNGDMF-SFNAEVVFPQASAIKIPVLMSMYKQAH -EGKFSLNDTRQVAAADAVGGTGVLKDLDGPPMSIRNLGILMITLSDNTATNTLIDLV-SM -QETNAMLRSLGAKHTLLQRRMINAAAS-GRGEENISTPADAAKILQLLYKGEFINKATSE -EIVSILSKTDRQTSRLAPGLPDNVPVAFKPGILN-GVSTEWAIVLLPER-PYVVAVMESY -KV--KGQAERTVEELSEVLYQYf ->[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC665 TaxID=2711216 RepID=UPI0013EA38D9 ---ELGARIEKLVKEHKGKATVALKNLKTGETF-SINPDEPMPTASLIKFPVMVEAYRQAA -EGKIDLNAPVTLRKKDMVPGSGVLTYHFSDGFPLVDAVHLMITYSDNTATNIVLDAV-GI -GSTAATMEKLGYPNTKIHSKVFRRDTSVFPDRSGSTTAGEMVKLFEALQAKKLVDEKSSE -AMWKHLLTCDD-KAKFPRFLPAGTKVAFKTGSVDE-ARTCAGVIETKGG-PVALCVMTNA -NEGDENAGNVLCAKTAREVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Cerasibacillus quisquiliarum TaxID=227865 RepID=A0A511V2E8_9BACI ---TLIQQIEKTITDSNGEWGVVLEDLQTKETW-TYNEHEQFPAASIIKLPIMVAAFQAAE -DKILRLSDTYSLSHDDLVGGSGVLQHMTPGTITIHDLITLMIIQSDNTATNILIDLL-EV -DYIQKIMEDIGMHESEFYNKLMIVPVK--RKGANTITAKDVSHLLKQLVQGALVSEHACE -QMIEIMKKQQI-SDGFRGKLPSQWQLANKTGHITN-VQHDAGIFYVGYR-QLIATVLIKN -LE-D-YKANTSLMQLGETIYQY- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A2C6C9Z4_FUSNP --tEWKKEIEKIISQVDGKVCINFYDLNKNNGF-SINGNEKVLSASMIKLLILAELMKKNS -ENKFSLSNTIMIANSMKTGGDGILKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYFPSDIKIAHKCGDLDN-LENDGGIIWIGDR-IYILVVLTSG -MS--NLQCKQTIGKISKFIYDK- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8QV74_9BACT ----LEGKVRGLIAASGATVAVAFRDLQTGREL-LLNPGVSFHAASTMKVPVMLEIYRQAQ -FGKLSLDERLPVKNESIADGSTFSYKKIGGTETVRELLRLMITESSNLATDILIERV-TP -ARVMELMRRMGARDMRVLRGVEDGK-AFERGLNNTTTARDLLVLMRAIAEERAVSIIASR -EMARVLLDQKF-NEGIPAGLPPLIPVAHKTGSITK-IEHDAGIVFLSGRKPYVLVVLVRG -IAE-EARAHKLIADISRAIYE-- ->[subseq from] serine hydrolase n=3 Tax=Enterobacteriaceae TaxID=543 RepID=UPI0013A6351E ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPT------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B9TL01_PSESP ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRIE -QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVSEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STTQAERALRGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus chromogenes TaxID=46126 RepID=UPI000D4C05C2 ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVVSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDR----------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=filamentous cyanobacterium CCP4 TaxID=2107699 RepID=UPI000D12CC7F ----LKGELENLATLTPGTPVAFAVDLDSGQYI-DLGGAEPVAAASTIKVPILIAFLQQVD -AGTVALNQSLMLQEEYMAGGSGTLREAVGTEYTALDVATRMIVASDNTATNMMIAALGGI -EALNQTFAGWGLEHTVLRNPLPDLDGT------NTTSAKDMALIMALVDQGGLLTPRSRD -RLFSIMQRTEN-VSLIPSGISDRSLTAHKTGDIG-GLLGDVALVDVPNGKRYTLALLVQR -PTND-GRASELIRRMTETVH--- ->[subseq from] hypothetical protein n=1 Tax=Leptolyngbya sp. KIOST-1 TaxID=1229172 RepID=UPI00069115A7 -------------------PVAFAVDLDSGQYV-DLNGAEPVAAASTIKVPILVAFLQQVD -AGTLALNQSLMLQEEHLAGGSGTMREAVGTEYTALEVATRMIVASDNTATNMMIAALGGT -AALNQTFTGWGLEHTLLRNPLPDLDGT------NTTSAKDLALIMALIDQGGLLTPRSRD -RLFSIMQRTEN-ISLIPSGIGDKSLTAHKTGDIGS-LLGDVALVDVPNGKRYTLALLVQR -PTND-GRASELIRRMTEVVH--- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum subsp. polymorphum TaxID=76857 RepID=A0A2B7YH17_FUSNP --tEWKKEIEKIISQVEGKVCVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS -EDKFSLSDTIIMANFMKTGGDGVLKVLNTGHFTLKELATLMIIISDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A5C6K354_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGHNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T0G8_9BACT ------DHLARLERDHGGRLGVCVLDAGSGREL-HWRGDERFGMCSTFKLPLAATVLHAIR -AGELDGDEAIGFTQDDLVPHAPVIQSRLDAGMTPVELAQATQLTSDNVAANLLIRRLGGP -EAVTARWHAFGDAITRLDRWEPAMNLVPPGEIRDTTTPCAMARHVARL------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4V1ZP77_9BURK ---RLEKALAGIDAQGTAKIGVYVRDLDTGVAA-SWKADQRWYLASMVKVPVAIAVLRGVE -REQYTLDTKVSLRASDYVDGAGRTNSYKVGRLSIRFLLDQMIIYSDNTATDMLIDLV-GA -AGVNAVVESLVPDRFREITSLSDVRHAYYASGVNSAPLTAYADLLQLLADGKALTPRYTD -YLLKVMERVATGKNRLKAGLPPDMKFAHKTGTQRR-RICDAGLLRFAGRERRAIVVACVR -DEPSLVISEHALVQVGAAICK-- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009906B5E ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium sp. SYSU L10167 TaxID=2666329 RepID=UPI001391CA1F ---ALEEGILSLMQATEGDFGMAFRMLDSGREL-LINEKEVFHAASTMKTPVMIELFKQAG -AGKFDLQDSILIVNESIVDGSPFSYERIGEKTTIYELMYQMIIKSSNLATNILIDLV-GA -EKVTQSMRELGAEDIEVLRGVEDLKA-FEAGLSNTTTALDMMLIMEAIALGNV---EGSE -EMVTILSDQYF-KDLIPKLLPADVKIAHKTGSIT-GVQHDAAILELPNGNRYVLVILSKN -LA-DVAAGKETIAQISRLVFEY- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC3DE1 --sKLEQTIQELAASIDGRVAVFIEW--DEGRV-SLNEQEAFPSASLIKIPIMLEALRQEQ -VGQTDLNTSLAIPAEERVGGMGVLADLSSEILPLRDLVTLMIAISDNTATNLVIQKV-TM -EAVNQLAAGLGCQHTVLARKMMDTEA-VRQGKDNYTSAQDIGLLLKEIITGDTLDSSRKE -AAFQMMRQQQF-HTKLPAELPPDASFAHKTGELA-GIEHDAGILKMGDR-YITMAVLTRD -LA-DEAAGREFIAKVGKAVFDTf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HIS3_9BACT --------FEKLEHWTAGRIGVAAVNTADNSSL-QYRGDERFPLCSTFKLMAAAAILHRSL -DEPDLLKKHILYSATEVTAYAPVTIKHLSTGMSIADLCAAAIQYSDNAGVNLLMKELGGP -KAVTAFAQTIGDNLFRLDRWEPELNSAIPNDPRDTSTPASTISGLYRL------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Parabacteroides merdae TaxID=46503 RepID=A0A3E4ZMR6_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGVNEAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI0012922B96 ----LTDSISQIVSACPGEIGVAVI-INNTDTV-SVNNKSIYPMMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPRSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGCNGAQNDVAYICLPNKVCYTLAVFVKD -FKGNESQASQFVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5PTD4_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -GRVEAVRKALNLKTTDLKATIDEAYDRYYKTNVNSATLEAYGDMLEKLVKGQLLKPPSTQ -LLFTAMKIDIFTNYRLQAGLPRSEKFIHKTGTQYR-RACHVGVINPQNGADAIVVTTCAA -DLDEQKQAGRVFQQVGQAITK-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium coskatii TaxID=1705578 RepID=A0A166SWV4_9CLOT -------KILAAIDLKKLNCAFVIENLKTGEKI-AYNENVVVPSASLIKIPIMMEILNQVK -EGKLSLKQRITVEDNVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM -DNVNNYVKNLGIKNTVLQRKMMDSEAR-KEGRENKTTAAEMAKFFEIIYKGEKAKGSYSV -IMKNILTSQLD-NSVMRLNIPDDTLIAHKTGDLD-GISHDAGIVYLPNVD-YIFCGLTWD -AV-TNNFARETIGKISKIAYDYf ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides eggerthii TaxID=28111 RepID=A0A414M273_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADYNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. 141 TaxID=2056666 RepID=A0A2M9TDX4_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -------ARTLGVSPSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ -TLLEVMQRTRSGEQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG -PL-ALSAHEQALTRVGEALHD-- ->[subseq from] Class A beta-lactamase, subclass A2 n=6 Tax=Bacteria TaxID=2 RepID=A0A641QV39_BACOV ----ISDSISKIASEYPGEIGVAVI-INNQDTV-TVNNKSIYPMMSVFKVHQALALCNDFD -KKGSSLDTLVKINREKLDPWSPMMKDYSTPVLTVRDLLRYTLIQSDNNASNLMFKSMLNT -AQTDSFIAKIPRSSFQIAYTEEEMLADHDKAYSNYTSPLGAAVLMNRLFTESLISDDKQS -FIKNTLMECKTGMDRIVAPLKEGVVIAHKTGSGFNGAHNDVAFIRLPHNKYYTLAVFVKD -FKGNETQAAKIIARISNTVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Chryseolinea soli TaxID=2321403 RepID=A0A385SNN0_9BACT -hdKVKETITQALAAQQGTFAVAFKDLSTGEEI-FINERMPFHAASTMKTPVMIEVFKQAA -AGKFSLTDSVLIKNESIVDGSPYGYRQIGKKRTLQSLVYEMITVSSNLATNIVIEWV-DA -KNVTQTMRDLGAKDIQVLRGVED-NKAFEKKLNNTVTAYDLMLIFEKLGKGEAVNPEASK -AMIAILLDQKY-NDIIPAKLPRDVKVAHKTGWIK-GLHHDSALVMLPDGRQYVLVLLSKD -LK-DEKAAVETLNDVSKTLYDY- ->[subseq from] serine hydrolase n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013A62298 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPT------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T354_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQEISLDALCGATMRTSDNTAANKVLEALGGP -DAVTAFMRAMGDEVTQLDRWETELNEATPRCRR--------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus vulpis TaxID=2325572 RepID=A0A544TRP1_9BACI --kKLISKIQDLIGQSEGIWGIVLEDLDLGEKW-ELNGEELFYAASVIKVPVMATIFSAVE -RGELTLTDQILLKEKDFVGGSGVLQHFTPGTLPIQDIIMLMIIQSDNTATNILIDLV-GV -ENIVRTMNEAGMEKSTFYNKLMMNNPNPK--GFNQVTASDIARLLKLIASGELVSSEASE -QMISIMKKQQI-KDCLPEKLPSPWELAHKTGWIP-GTRHDVGIFYVGQR-RLIATVLSKE -VD--DLMSKRILSEIGEEIYNY- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=UPI00125F6D87 ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGNNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella denticola TaxID=28129 RepID=Q8KT56_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQVLALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Lysobacter alkalisoli TaxID=2591633 RepID=A0A514BSS8_9GAMM ------------------------------------------------------------- --------------------------------------------------------AAAGP -TRMHRLAELLGVTPADFHPDIDSAFEAYYATHVNTAPLRDFGRMLVTVANGLALGQEGTT -YLLDTMTRAKTGEKRIKAGLPPEARFAHKTGTQHR-RACDLGIVLMPAGEQVVIVACVRG -PA-SVAQSERALREVGAAVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Salinimicrobium sediminis TaxID=1343891 RepID=A0A285X1Y8_9FLAO --qKTEQRLQEIFNTSPAITGLVAVDLTSGEKI-GWNSEVQFPQASSIKIPVLMEVFKQAH -EGKFSLSDPLPLTSENTVGGTGILKHLEDPALSIKNLGILMIALSDNSATNALIDLV-GM -SEVNSTLKSLGMTNTLLQRKMMNSEA-SARGEENLATPADAAKILQLLYKGEFVSPEVSN -EILDILKMTDREDSRLAAGIPENVPIAFKPGFIS-GVSTEWTIVLLEQR-PYAVALMESN -KLP--GEAERVMEEVSEILFNYf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A0N9HJB5_9BACT -------------------------------------------------------MLSEID -KGSFRLIKRSRSRKSELLPSSPIREKYPDGALTIAEILEYTVSKSDNAGCDALLRLLGGP -QAVENYFVKNKFKDIAIKINEEVMQGNWDLQFQNWTTPKAADKVLEAFYSNKLLSQKSYA -FLWKVMRETETGANRLKGQLPDGTVVAHKTGWSGTAAVNDIGVVFLPDGKHFFISVFVTD -SRENAETNEKIIADIAKAAWDHf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0009908747 ------------------------------------------------------------- ------------------------LEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGN -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase AmpC n=1 Tax=Marinobacter sp. HL-58 TaxID=1479237 RepID=A0A0P7ZGI0_9ALTE --eDLEKKLAGIDDRYPGELGVYVHNLEDGKTA-DLRAGETWYLASTIKVPVAMAVMEAVD -SGELTLDTDVELKAADFVDGAGETNKSPGDRVSVRYLFEQMLTHSDNTATDVLIRLV-GM -DAVNQLVRRYTDGGIGEVTTLADVRRGYYESGLNSGRLDEFSLLFEALAEQDGLSDDSSA -YLLSTLENIKTGDNRIKAGLPDHVTFIHKTGTQYR-RACNIGLVQMDDHPGVIIAACGRG -TQ-DLNASELAFRRVGEAVSE-- ->[subseq from] serine hydrolase n=1 Tax=Salegentibacter sp. Hel_I_6 TaxID=1250278 RepID=UPI00056D216F --eKLQQKIDSVFENTQGDFAIAFKNLSEEKDSiFINAHEDFHAASTMKTPVMIEVFKQAA -EGKFSLQDSLVIKNESILDGSSYAYERIGQKRSIQDLVTDMIIYSSNLATNIVIELV-DA -KNVNKTMRELGAKNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALSNGKAVNPEADK -QMLEILQQQKH-IDLIPALLPENLKIANKTGWIT-GVHHDSALIELPDGTKYVLVLLSKN -ME-NMDAGTKMLAEVSKMVYDH- ->[subseq from] MurNAc-LAA domain-containing protein n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A5Q4FF58_9BACT ---TLEQQILRITEAAEGDYAVAFIDAGNPETNlFIDADEWFHAASTMKTPVMIEVYRQAM -EGRFGLDDKLVVRNEFVSIGSTYSYDHLGSELSIRELVYSMIVRSGNLATNIVIEHV-GA -ENVNRAMADMGAEGIRVLRGVEDMEA-FRAGMNNEVTARGLAMMYLRLAEGSVLDETYRS -QVLSVLKDQHF-RDMIPALLPEGVTVAHKTGWIT-GVRHDSGIVYLPDGRAYVLVILSKN -VP-DRADANRTGAEISRRIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus yeomjeoni TaxID=291403 RepID=A0A327PTY7_9BACT --qMLQSTIQAQLDSIQGDVAVAFINLSDPSDSlFINASEEFHAASTMKVPVMIELFKQQK -QGKLDLNDSILLKNESIVDSSLYSYNKIGGKVTLKDLMYPMITVSSNLATNVLIELV-GA -KNVTATMRDLGAEKIEVLRGVEDQK-AYDLGLSNSTTAKDLMVIMKAIAEEKAGTKQDCD -EMIRILKDQQF-NEIIPFYLPKDVTVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LE-DFDKGTEQLAGISKTVYDH- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI0013FD88FC ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPT------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3E0NVQ3_9BACT ----LRGDVEALIEASGAEVAVAMRTLDGALEL-LIEPDLEMHAASTMKVPVMIELFRRAE -QGELTLADPIEVTNESIVDGSPYTYSAIGSERTLRHLCEAMITWSSNLATNILIDFL-GA -ERIQATTDELGASGMKVLRGVEDIKA-FDAGLSNSTTARALLVLLEKLGRGEVVSADASE -QMVAILRRQQF-GEAIPAGLPPGTVVAHKTGNITR-IHHDAALVEIE--RPYVLVVLVRG -IE-DRAQSAALIASIARRVH--- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium marinum TaxID=104 RepID=UPI0011EF141E ---QLEEEIRKLMNETEGDFALAFRSVDGEESElFFNEKETFHAASTMKTPVMVALFEQEA -AGKFSLQDSILIRNSSILDGSTYQYKRIGENATMYELMYEMIVRSSNLATNILIEKV-GA -KNVTQLMRELGAEDIQVLRGVEDLK-AYEAGLSNTTTALDMMLIMEAIAKHKV---AGSK -KMIDILSDQHF-NDLIPKYLPKEVKIAHKTGAIT-GVQHDAAIVELPDGNRYVLVILSKN -LT-DEKAGKECIAKISQMIYN-- ->[subseq from] serine hydrolase n=1 Tax=Halomonas stevensii TaxID=502821 RepID=UPI0012EAF5B4 ------------------------------------------------------------- ------------------------------------------------------------- -----ALARTLGVSSSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ -TLLEVMQRTRSGEQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG -PL-ALSAHEQALTRVGEALHD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A650AIC6_ECOLX ------------------------------------------------------------- -----------------------------------------------------------GP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDITVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLAS--------- ->[subseq from] Uncharacterized protein n=2 Tax=Cytophagaceae TaxID=89373 RepID=U5BJI8_9BACT ---ELESALLAELENAQGDFAIAFKTLDDPSQMvLINEKEVFHAASTMKVPVMIEMYKQAG -QGKFSMKDSIPIINESIVDSSLFSYERIGQQATYYELMYEMVTMSSNLATNILIEKI-GA -DNINATMREMGVLDNQVLRGVEDLKA-FDAGLNNTTTAYDLMLIMEAIAKGETVDSASSE -EMMDILIDQKF-NEMIPELLPKDVVVAHKTGAIS-GVEHDAAIVKLPDGRAYVLVILSKN -LE-DVEKGKSQIAQISKIIYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium 4484_49 TaxID=1970784 RepID=A0A1W9RGE6_9BACT ------NEVDEVLKKFKGKAGVVIVDLQNGWTI-ARNQNEKCPAASVIKLPIAVVVYKAIA -EGKVFRGQVIEIRRSDVVSGSGVIRKRNPRRYTLDDLVALMLTVSDNTACNKIISLL-GF -DYINTEMKKLGLQDTTLRRFMMDFKAR-DRGFENFTSARDIAEVWKLLYYEKILGEKESR -YLIELLKNQKV-NDRISGLLATRTIVANKTGLERN-VCHDSGIIFTPYGD-ILIVVLASD -FK-SFKLAKEFIATLA------- ->[subseq from] serine hydrolase n=1 Tax=Rubrobacter indicoceani TaxID=2051957 RepID=UPI000E5A1082 -------EAARTVEEYPGVAGFYVMDPKDGSGY-GVRPDEEFFSASTIKIAVMAAVYRKIE -SGELEYSDMLTTTEGDWAAGAGWLRWNTPGATTVEDALWLMMTESDNVATNVLLRTVGGP -EYVNSVSRDLGAENTNLFWKLSSERAAVP-ELDNRTTPRDMATMLAAIYSGDGLNDFSRN -EMIDLMRQNSL-EYWLEGGIPGGVTAANKGGWQD-GIYNDAGIVERD-GSPYVLAIYTMN -GP-ELEVGSPVLAEISGSVW--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RVY2_9BACT --kKLETRVEEIASSLDGVMGVAILDLTGGRIL-LRNADRVFPAASSIKIAILLELYRQDQ -KGKAKLDDIYTFDPKDLVEDSRIMAGLTAGVITNRDLAQFLVAVSDNAAANVLYDRV-GK -DNVNAMLHSLGLPKTLLRRKMMDIAAARRG-DENIATPQEMVRLLEAIFKEKALDKQATA -EFIKQLSTLKQ--SYLPRYVPESVQVANKPGELE-GVRTDSGIVFAQNQ-PFAISVMTAY -DR-DEKAAERAIGEVALEAYRYf ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7B7544 ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRIE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] B30.2/SPRY domain-containing protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9JZZ7_9BACT ----LALEMAKLAREFDGALGVYAKELNGGKEF-AYHADDPFATASLFKLPVMVELFRRVE -AGEVSFAKRLKPPETGISRGTGLIRSLKDQPFTLRDYCRLMIIFSDNIATDTLMQII-TP -QSVTATMKELGFPHTRVSGNCTLMHYADRSLNGNVTTPREIGLLFERLYRGQVVSSSASA -QMLEILKETTS--RKMASSLPSVIEVAHKVGSTK-GVSTDAGIIYMPKK-PIVLSLFTYS -ETAD-ARAGKLIADIGKLVAEEf ->[subseq from] Beta-lactamase class A n=1 Tax=Paramaledivibacter caminithermalis DSM 15212 TaxID=1121301 RepID=A0A1M6LHN7_9CLOT ----LRKKIDDIIEGVDGDVGVIVKNLETNESI-MINEDTVFPAASVIKLYILWELFERIK -KGEFTLEQEILLKESHKVGGFGVLKEHEGINLSLKDIATLMIILSDNTATNILIDLL-GM -DNINQTIKNNKMKDTVLQRKMMDGEA-KAKGFDNYTSPMDVLSILEKSL--------QRE -EIIDIMKRQQC-NNKLPALIDDSIVIAHKTGDLP-AVEHDVGIMFMENS-SIIIIVLTKN -LKEN-IEGIKLNNNIGKAVYDYy ->[subseq from] serine hydrolase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=UPI0007C80ADD -----ERQVERRILAAHADVAVFFRPLGGGSEW-SYKPDDTFHAASTMKVPVMIELFHQAR -QGKLALDDPLLIHNESLVDGSAFYYRSEGQTRTLRELCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARGLAILLTAIAQGKVVDPDSSR -QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-GIHHDAAIVY--GRQPFVLVILVRG -MTNS-EDSSALMADITRVFYR-- ->[subseq from] Beta-lactamase n=1 Tax=bacterium J10(2018) TaxID=2320122 RepID=A0A3L7ZYW6_9BACT ----LADTITKITSQYPSEIGVAVI-INNTDTV-TVNNSNIYPMMSVFKVHQALAVCHDFD -RKGLSLDSLMNIAREELDPWSPMMKEHLEPVLTVKDLLHYTLSQSDNNASNLMFKRLVDV -ARTDSFIATIPRSSFHIAYTEEDMSTDHDKAYANCTSPLGAAILMNRMFTDSLVSRENQL -FIANTLKECKTGNDRIAAPLKEGISIAHKTGSGYINAHNDVAYICLPDNTCYTLAVFVKD -FKGNEAEAAKAIAHISATVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534GHI7_9GAMM -------RIESVIERSGADVAVAFRTLDGRTQW-LRRADEPFHAASTMKVAVLIELYRQAR -QGRVGLDDPLRVKNESLVDGSAFAYRAAGGTRTLRELSELMITVSSNLAANLLMDKL-GV -ENIRAGVHALGADGMNVLRDLEDAK-AFERGLVNTTTAQALLALLDAIARGQAVDRESSR -QMLETLERQTI-NDAIPAGLPAGTHVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG -LEN-PKESTALIAEITRELYR-- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534CTH2_9GAMM -------RIESVIERSGADVAVAFRTLDGRTQW-LRRADEPFHAASTMKVAVLIELYRQAR -QGRVGLDDPLRVKNESLVDGSAFAYRAAGGTRTLRELSELMITVSSNLAANLLMDKL-GV -ENIRAGVHALGADGMNVLRDLEDAK-AFERGLVNTTTAQALLALLDAIARGQAVDRESSR -QMLETLERQTI-NDAIPAGLPAGTHVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG -LEN-PKESTALIAEITRELYR-- ->[subseq from] Uncharacterized protein n=2 Tax=Planctomycetales bacterium TaxID=2053591 RepID=A0A5K7XDI2_9BACT --qQMQARLQAIADGVDGTFGLVVEDLAGEHAF-AVNSGRHFTQASCIKTPILMEVLKQAH -EGKFALTDRVRVEQQDKTTGSGVLFELGNGSLSIEDLCVLMILLSDNTATNLLIDRV-GM -ENVTATMESIGCGQTVLRRRMMDMAAA-ARGEENRSTPADAARIMRLLKEGKFVNQAVSD -HALAILRKSKSG--AIRSTVPLSVPVPFKPGELP-GLLTEWALVELPERPYIVIAMGTYN -PKSTDDDLDAAMKLVGKEAYKFf ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas songnenensis TaxID=1176259 RepID=A0A482U6N6_9PSED ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRIE -QDDLTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGTGFAHKTGTQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALRGTGEAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. SAJ1 TaxID=2497750 RepID=A0A3S0N9P3_9BACI --------------TTGGTWGIYLEDLDKNETW-SWNENEVFYAASIIKVPIMAAVFSAFD -EGLFKLSDTIVLKREDLVEGGVLQHLTPGIRLTIYDYLTLMIIQSDNTATNVLIDLV-GV -KKIQEMIAEIGMKNSCFYNKLNTVPVK--TNGRNMITARDMAVLLKKLTSGMIISQYACE -QMIDIMKKQQF-RDCLPYKFPETWEFANKTGWVT-GIRHDIGVLYVGRR-TMNIVVLSKD -VE--DKLAKQTMAQIGECIFNY- ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344THH1_9BACT ---RLKEAIQAKLSGIEGNFGIAFKDLQSNQTL-FINEKENFHAASTMKTPVMIEVFKQAK -EGKFKLTDSILVKNESIVDGSTFSYKMIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KKANATMRDFGAKDIQVVRGVEDSK-AFQLGMNNSVTAYDLMVIFEKIARKKAIDRTSSE -GMTDILFDQKF-NEIIPAKLPKEVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLILLSKN -LK-DPKAGVRTLADVSEMIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium nucleatum TaxID=851 RepID=A0A3P1VRG0_FUSNU --tEWKKEIEKIISQVEGKVYVNFYDLNKNNGF-SINGDKKVLSASMIKLLILAELMKKIS -EDKFSLSDTIITANFMKTGGDGILKELNTGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKETSQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENDGGIIWLGGK-AYILVILTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium nucleatum subsp. animalis 11_3_2 TaxID=457403 RepID=F7L0T3_FUSNU --tEWKKEIEKIISQVKGSVCINFYDLVKNTGF-SIDGNKKVLSASMIKLLILAELVKKVS -ENKFSLSDAITVTEAMKTGGDGVLKELNSGHFTLKELTTLMIIVSDNQATNILIDFL-GM -ENINLLGKELRLKETFLGRKMMDAEA-RKKGYDNYTCADDISLLLKLIYQEKLINKEASQ -LMLDILLRQQQ-GERLQRYLPSDIKIAHKCGDLDN-LENNGGIIWIEDKA-YILVVLTNG -MP--NLQCKQTIGKISKFVYDK- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella sp. ICM33 TaxID=1161412 RepID=UPI000684045F ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=2 Tax=Prevotella TaxID=838 RepID=F0H4M5_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella salivae F0493 TaxID=1395125 RepID=U2MSJ8_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=2 Tax=Hazenella coriacea TaxID=1179467 RepID=A0A4R3L531_9BACL --qTLKARLNQWHEKAVGQWGIWIEDLADQQTW-TVNEDQTFYAASVIKVPIMVAVYQQAW -KGQFSLEEKIPLTKEMQVGGSGVLQHLSVGTLSIQDLITLMIIQSDNTATNLLIQLV-GK -KTIQQVMKDLGMEQSAFYNPLMIVPV--EREGVNLITAADVAACYRKIAKGEAVSYHHSL -QMIHVLKNQQI-QDCFPSQLPAPWELAHKTGMINR-VLHDTGILYLRDRA-FLLVALSAD -CS--YEEARQQLGELARIVWEVy ->[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus TaxID=400634 RepID=A0A0A3I7H8_9BACI ------EKIRPLVEEVDFKVHLFLKEMESEQFIlSENLDDGFSSASLIKVPILVAVLDYIE -QNKLSLYSELKIHSQNKVDFSVVTEQDLDE-CTLYELLVWMIITSDNSATNVLIDFI-GM -EKLNVYFNRIGLKATKLQRKMMDFER-LQQGYDNVTNARDMAYLFTSIYEQTLLSEQYSN -LVLDILSRQRV-HEGLKRYISGDVQMAHKTGSLDS-VFHDTGIVYLDSKD-YIIGVFTTQ -LS-DVEAGKRLIGRISKIAYEYf ->[subseq from] Beta-lactamase class a n=2 Tax=Leptolyngbya sp. Heron Island J TaxID=1385935 RepID=U9W143_9CYAN ------------------TPTIYMFDLDTGNYV-DVAGNAEVAAASTIKLPILVAFFKAVD -DGRITVDQTLAMQSSQIAGGSGDMQVQPPGTYTALEVATQMIINSDNTATNMMIDLLGGA -PELNQQFASWGLTMTVLRNPLPDLEGT------NTTSAQDLVRMLAHLHKGEILSLRSRD -RVMNILQRTYN-KKLLPAGVSETTVSYNKTGDIGS-VLGDVALMDLANGKRYAIAALVQR -PEND-GRARELIRRISQTVYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Limnothrix sp. CACIAM 69d TaxID=1890733 RepID=A0A372DP46_9CYAN ----LSDQFQKIAARYSLILHAAALDLDTGDFA-AWNDTRSVAAASTIKVPILVAFFQDVD -AGKIRLDEMLTMEARFVAPEAGTMQQKPGQKFSAIDTARQMIVISDNTATNMIMARTGGS -GPLNQRFQSWGLQGTNIRDLLPDITGL------NRTTARDLVQLTALINRGELVSIRSRD -RLLSIMRGTAA-NSLLPKGIGKGGEVAHKTGTLAK-LLADTGLVDTPNGRRYGIAVLAER -APND-PKAAEAIRDYSRAAYNHf ->[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537JDF1_9BACT ----LQGVVEGAAARVSGRLGCCVCP-ETGTPWaIHRAEETFATASVIKAPIAVAVAAEVE -AGRLEWNQLLPPHLRDDAGDSGVIRHLSPLPYTVRDLVFLMLVVSDNRATNLLVDLV-GM -ERLNASFARAGWERTSLARRLGDFEAR-ARGLENRSTPRETCDVFLRLLRGDLLSPGSRT -LLLEFLKAQVY-RDRLPARLPRTTAVAHKTGDMP-GVENDAGVLYLPAG-PIVAAVFTNE -LA-SDVEGRLAIQEIGRAIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Blastopirellula cremea TaxID=1031537 RepID=A0A368KK79_9BACT -----SALLLPLIEKHRGDVGVVIQHFPSGESF-AYQADKPMSTASLIKLPLLMATYAKVH -DGGVSLDTMITLTEADKVPGSGILTKHFSPGLSLRDAIQLMVAYSDNTATNLVIDTV-GL -DTTNTLMKKLGCDETRLNSKVFRRDTRSKAFGLGSTSANDMQRMLRALHDRSFVDQATSE -QILKHLYDCED-RMKAARYLPANVKVAHKGGSVN-AARTDAGIIDLPDGGAILFCVLTMN -NQTDDNEGDVLSAKIGKAVYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A660WPM8_9BACT ---NLKREILDLTTSFEGEISFLVKKLRFPSKI-SSREELIFPAASLIKLPLVAVALKAIG -EGKISSQEYITIKKEDIVGGSGIIKKMKTPFVHFERLCELAISYSDNTATNKIIDIL-GF -DYINENFKKIGLKNTFLERKMMDFRKR-SRGIENYTTTLDITYLLEKIYRGGILDKDASK -VLLSFLKKQKV-RDRLPRYLPKEIIVAHKTGLEK-GVVHDAGIVFTSRGD-YIICVLTKG -VK-NYERAKKIIAEISLLAYTFy ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A496S9Q2_9BACT ---NLKREILDLTTSFEGEISFLVKKLRFPSKI-SSREELIFPAASLIKLPLVAVALKAIG -EGKISSQEYITIKKEDIVGGSGIIKKMKTPFVHFERLCELAISYSDNTATNKIIDIL-GF -DYINENFKKIGLKNTFLERKMMDFRKR-SRGIENYTTTLDITYLLEKIYRGGILDKDASK -VLLSFLKKQKV-RDRLPRYLPKEIIVAHKTGLEK-GVVHDAGIVFTSRGD-YIICVLTKG -VK-NYERAKKIIAEISLLAYTFy ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A496RI38_9BACT ---NLKREILDLTTSFEGEISFLVKKLRFPSKI-SSREELIFPAASLIKLPLVAVALKAIG -EGKISSQEYITIKKEDIVGGSGIIKKMKTPFVHFERLCELAISYSDNTATNKIIDIL-GF -DYINENFKKIGLKNTFLERKMMDFRKR-SRGIENYTTTLDITYLLEKIYRGGILDKDASK -VLLSFLKKQKV-RDRLPRYLPKEIIVAHKTGLEK-GVVHDAGIVFTSRGD-YIICVLTKG -VK-NYERAKKIIAEISLLAYTFy ->[subseq from] Uncharacterized protein n=1 Tax=Pontibacter sp. S10-8 TaxID=1797110 RepID=A0A1Q5PHW7_9BACT --qQTEKQLHDIISRSPAVTGLVAVDLTSGDTF-AFNPDVVFPQASAIKIPILMNVYQQAH -EGRFSLTDIRKVSPADVVGGTGVLKDLKTMPTSIYDLGVLMITLSDNTATNSLIDLV-SM -KEINAMLRGLGAKQTLVQRKMINAAAS-GRGEENLSTPADAARILQLLYKGEFISKATSK -EIISILKRTDRQTSRLAAGIPDAVPIAFKPGVLN-GVSTEWAIVLLPER-PYAVAVMESY -KV--KGQAEETVEQLSEVLYQYf ->[subseq from] Beta-lactamase class A n=1 Tax=Leptolyngbya sp. PCC 7375 TaxID=102129 RepID=K9FLX9_9CYAN ----LKTKLEELQELIELTPTIYVFDLDTGNYV-EVAGNAETPAASTIKLPILIAFFKAVD -EGRITVDQALAMQSNQIAGGSGDMQGQPPGTYTALEVATQMIINSDNTATNMMIDLLGGP -QVLNQQFVDWGLTMTILRNPLPDIEGT------NTTSAQDLVRMIAHLHKGDILSLRSRD -RVMNILQRTYN-KKLLPAGVSETTISYNKTGNIGE-VLGDVALMDLANGKRYAIAALVRR -PEND-GRAQELIRRISQAVYQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Prevotella intermedia TaxID=28131 RepID=C1M2W2_PREIN ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNVSYTLAVFVKD -FKGNESQASQYVAHISAVVY--- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534FCD3_9GAMM -------AIESTIKKSGADVAVAFRTLDGRTQW-LRRPDEPFHAASTMKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFALYRAGPGRSLRELSELMITVSSNLAANLLMDRL-GV -ENIRAGVRALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR -QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLAS--RPFVLVVLTRG -LEN-PKESTALIAGITRELYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A660WMK1_9BACT ------NEVDEVLEKFKGKAGIVIVDLQNGWTI-ARNQNEKCPAASVIKLPIAVVVYKAIA -EGRVSRGQVIEIRRLDVVSGSGVIRKRNPQRYTLDDLVALMLTVSDNTACNKIISLL-GF -DYINTEMKKLGLQDTTLRRFMMDFKAR-DRGFENFTSARDIAEVWKLLYYEKILGEKESR -YLIELLKNQKV-NDRISRLLATRTIVANKTGLERN-VCHDSGIIFTPYGD-ILIVVLTSD -FK-SFKLAKEFIATLAF------ ->[subseq from] FRAMP1.1 beta-lactamase n=1 Tax=Prevotella sp. CAG:1124 TaxID=1262920 RepID=R5KV81_9BACT --qTTEEKITDIINGKPAKVGVAWIV--DGKEH-SVNNADCYPLMSVFKLHGAIAALRQME -RRGTPTDTLVRINASQVTRYTPMLERYPESGIRFDSLLQYSVAESDNNACDIIISMAGGI -EDVNAEMCAIGLADYSLSETEISMQADPMRSYDNCSTPLSVAILFKKLFEENILGEPYAT -LLKHILISTTTGQDKIKAALEPGMLIAHKTGTGFDGADNDAGVVLLPDGRRIYISALVKD -SKLGSKENAKLIADMARIIIR-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella sp. P5-108 TaxID=2024225 RepID=UPI000B9712BB ----LTDSISQIVSACPGEIGVAVI-VNKKDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Halomonas sp. BC2 TaxID=1670449 RepID=UPI0009C0032C ------------------------------------------------------------- ------------------------------------------------------------- -----ALARTLGVSSSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ -TLLEVMQRTRSGEQRLKRGMGREVTFAHKTGTQHR-RSCDAGIATRDGAQHWVIVACSRG -PL-ALSAHEQALTRVGEALHD-- ->[subseq from] Class A beta-lactamase n=2 Tax=unclassified Muribaculaceae TaxID=2006847 RepID=A0A3N2KNW8_9BACT ---RLQNELTSFVERKDARIGIAVI-INGKDTV-SVNGSKDFPMMSVFKFPLALAVAKWVD -SNGMSLNDSIAFGPKALIKYSPMLKKYGSGLMSFKELLEWSLIESDNNAADLLLKRVGGT -ACATTLLKDAGELDITIGASEQEMHKDPYTSYLNRSTPLAMATLFDRFDTDIKARSKSFS -NISVMLEQCRTGVDRLAAPFATNAVVGHKTGTGFISAINDCGYIHLPNGTRYTIAVFVAD -SGYDMTETSKIIADISEIVFK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Echinicola vietnamensis (strain DSM 17526 / LMG 23754 / KMM 6221) TaxID=926556 RepID=L0G3T4_ECHVK --eTLRNQITAHLSEVQGDFAVAFRSLGSDTLSlMINEKESFHAASTMKTPVMIELYKQVA -LGNISLDDSITVVNESIVDGSPFSYGKIGQKSTYKALNFQMITMSSNLATNILIDKL-DA -KKVTQTMRDLGAKDIEVLRGVEDLK-AYEQGLSNTTTAYDLMVIMEAIAAGKAVSKEASA -AMFEVLKAQHF-NEIIPGLLPENVTVAHKTGSIT-GVRHDSGIVELPSGERYVLVLLSKN -LKAP-EKGIQVMAQISKLIYK-- ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus massiliensis TaxID=1852375 RepID=UPI0009F53543 ----------------AGPAQVYFTNLATNQSI--YLGSETMPSASMIKVFILAKAYEDIQ -DGRLSRKETFTLTSDNVVGGAGVLQGRGYGSVPLQEALELMITESDNTAANLLIDRL-GM -DRINAYMQSHGYTHSVLRRKMMDTE-AMEAGRENLTSTRDIALLFKRLYQGKCVGPAQDR -EMLAIYKRQTD-NDSIPGDLPQGTVVAHKTGEVND-LRHDGGIVYTPKGA-YVLVIFTRD -YTPY-----GTMAELSEKI---- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=39 Tax=Bacteria TaxID=2 RepID=A0A630ZBQ7_SALET ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=unclassified Prevotellaceae TaxID=224765 RepID=UPI00094E81AD ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella salivae TaxID=228604 RepID=UPI0005673B24 ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. P4-51 TaxID=2024228 RepID=A0A255UGR8_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Thermobaculum terrenum (strain ATCC BAA-798 / YNP1) TaxID=525904 RepID=D1CF14_THET1 ---SLQERIANIIDSV-GYFGVAAKDLTQGREL-FINADETFNTASVIKVPIMIELFRRVY -EDNVSLDDRLILEDRFRTGGSGILKEFRSGLLTLWDLCVAMIALSDNVATNMLIDYL-GI -DAINRCMDSLGAHNTRLHRMV-GFKSIKPDQPKGRTTPRDMMMIFQKLAEGNVISESASE -EMIAILAKQHD-RNMIPRLLPDSAIVANKTGAVD-GVRNDVALIRFADGRQWVICILTKD -LRKVDHEGEIAIAKIALEIYKEw ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534IKU6_9GAMM -------RIESVIERSGADVAVAFRTLDGRTQW-LRRADEPFHAASTMKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFAYRAVGATRTLRELSELMITVSSNLAANLLMDKL-GV -ENIRAGVHALGADGMNVLRDLEDAK-AFERGLVNTTTAQALLALLEAIARSQAVDRASSR -QMLETLERQSI-NDAIPAGLPAGTHVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG -LEN-PKESTALIAEITRELYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Lentibacillus amyloliquefaciens TaxID=1472767 RepID=A0A0U4ED90_9BACI --kQLEADVRSIISGFHSPVGITIKN--ETETL-NINANSRMPAASVIKIPIIMEAFRQAE -NGGLDLSETLSVPADTIVGGSGVLQALSEDVMTVLDVLTLMIIVSDNTASNLALKWV-GI -DHVNRLCRELQCHHTEIQRYFMDMKAA-EEGLENTTTAGDMVNFLEEIASPWLLSRNSAK -RILHIMTRQQLSSKLPAYHTNDDIIMANKTGELAD-AEHDVGIFQFQERT-VFAAVLMDR -VS-DHVAARQAIARIGKMIMD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Omnitrophica bacterium TaxID=2035772 RepID=A0A419DWM9_9BACT --qELGRHLKSEIDQFKGEAGIVIKDLHAGWEL-SYQKSKLFPSASLAKIPIMAGCFLAAE -QNLIKLNRDISLKSTDKLTGSGMLKDLPAGKFSVDRLIGFMIYDSDNTATNILTDLL-GI -DYLNKTFQDFGLQNTFLSRKIADYRSR-DKGLENYTTAEDMVLLLEKIYRRALGNKSVSD -RCLRILKLARM-NDRIPKYLPPEITVAHKTGLEK-GVCHDTGIVFTCSGD-FIIVVLTKH -ADANSAPSKEFIARISLQAYKYf ->[subseq from] Beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A3S9W079_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=2 Tax=Halomonas pantelleriensis TaxID=48727 RepID=A0A1G9M525_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- ---VAAFAERLGLAELALDGYDAAF-DAYEAGRLNTGTLAAFGDLLATLVRGGGLSDASRE -ALLTIMQRTSSGEARLKAGFGDDVRFAHKTGTQHR-RTCDAGIAHRGEAREVAVVACTRG -PI-DVVPHERLLAEVGAAI---- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Leptolyngbya sp. TaxID=47254 RepID=A0A2W7A8I8_9CYAN -----RGELEQLSTLTPGTPVAFAIDLDSGQYV-DLGGAEPVAAASTIKVPILIAFLQQVD -AGTMALNQSLVLQEDSMAGGSGTLREAVGTEYTALDIATRMIVVSDNTATNMMIAALGGI -EALNQTFVTWGLEHTVLRNPLPDIEGT------NTTSAKDLALIMALIDQGGLLMPRSRD -RLFSIMQRTQN-DSLIPSGIRDQSLTANKTGDIG-GMLGDVALVDVPNGKRYGLAVLVQR -PSND-GRASELIRRMTETI---- ->[subseq from] serine hydrolase n=1 Tax=Proteocatella sphenisci TaxID=181070 RepID=UPI0004B7A781 -------SITQKLKALPGKTGFFYKNLETGETI-AWNENEKFIPASVIKLPVLMAIFNLAE -SRAADLTEYIKIKQEEKMPSCGALNSFTGEPVDIRTLCNLMITISDNTATNVLISHF-GT -EKLNEVFTDMGLADTRVNRKLFDMEAS-KKGIQNSATPKEMAYLLEELHFNRFINEKVSE -DIKEILHRQQI-NHKIKEMLPPGTRAAHKTGEDDY-ISNDVGIIYAK--QPFIFSFFSND -TKVSD------------------ ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2N8S1C6_PSEST ------ARLAHVDRQTPGQLGVYVKDMETGISV-SYHGEEPWYLASTVKVPVAIAVMRQTE -QGELTLDSPVALLASDYVDGAGPTNSHAPGKLSVRFLMDQMLIHSDNTASDMLIRLV-GI -EQVNAIAQELAPEGLGPITSLADVRRRYYATPFNSGTLKAYGDLLSALDAGIALKPESTE -YLLSVMRRVQTGKQRIKAGLPPGTGFAHKTGTQR-ARICDAGLVDQPGSTRLIIVACVRG -V-ASASQAERALRGTGEAVT--- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella pectinovora TaxID=1602169 RepID=A0A0D0I3H3_9BACT ----LTDSISQIVSACPGEIGVAVI-VYNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FB8AA -----------------------------------------FAMCSTSKVMAAAAVLKKSE -SEPNLLKQRVEIKKSDRVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKA------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF56402 --eALGAQIDRIDRATPGELGVYVKRLNGGETH-RHGAERFWYLGSMTKVPIAIAVLQQVD -AGKLKLSDSVELQDADRIDVSRVVRERTGRRYTVDALLDRMLKDSDNTAANMLIRTV-GE -DTVQRSAQALGTQGFK-------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Xenophilus sp. E41 TaxID=2282216 RepID=UPI000EF56402 ------------------------------------------------------------- -----------------------------------------------NTALVQVANAPLGP -GRVQAVQRALKLKTGDLQRTIDDAYDRYYRHDINSATLDAYGAMLEKLARGELLQPASLQ -RLYAAMKLGTFTNHRLQAGLPRSEPFIHKTGTQYR-RACHAGVLRPQDRADAVVVAVCAA -GMDEHKDVDAIFQQVGRAVAQ-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9LBQ4_9BACT -haRLAAEMDRVAERLNGVLGYAIKDLSTGEVF-YRNADLVFPTASSIKLTVLLELMRQAQ -EGELSLDEKHTVRRSETPATEPILHFLGDGTMTLRDLATFMVVLSDNSATNILIDRA-GM -DNVNAEIARLGLKETRLRRHMIDIDAA-RRGNENVSTPRELMILLEKVRAGGVLDSAHTK -EYFDLLALPK--DSLFNKALPSTVRIEDKPGALD-AVRCDAGIVDVPGHA-LAMSLMTTY -LAG-NDEGERAVGEIARLAYAHf ->[subseq from] serine hydrolase n=1 Tax=Blastopirellula cremea TaxID=1031537 RepID=UPI0011C01A21 -----SALLLPLIEKHRGDVGVVIQHFPSGESF-AYQADKPMSTASLIKLPLLMATYAKVH -DGGVSLDTMITLTEADKVPGSGILTKHFSPGLSLRDAIQLMVAYSDNTATNLVIDTV-GL -DTTNTLMKKLGCDETRLNSKVFRRDTRSKAFGLGSTSANDMQRMLRALHDRSFVDQATSE -QILKHLYDCED-RMKAARYLPANVKVAHKGGSVN-AARTDAGIIDLPDGGAILFCVLTMN -NQTDDNEGDVLSAKIGKAVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3M4L5_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQALARALDDADTFQVRTMDEAYDRYYRHRFNTATLTGYGAMLENLVRGKLVTPAHQQ -ALFKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQLH-RACHMGVIAPQDGQSAIVVATCAE -GLDEQKEAGKAFEAVGRAITQ-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides TaxID=816 RepID=BLAC_BACVU ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNKSQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA15(2017) TaxID=1932111 RepID=A0A1Q9Y4Z0_9PSED ----LLERLQATAARQDGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE -RGDWQLDTRLPLAANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-GL -DAVNGLVRELVPEGFEPITTLGDVRRAYYSSNLNAATLSAYGELLERLAEGQALGQAQTA -YLLEVMGRVKTGSKRIIAGLPKNTHFAHKTGTQR-ARICDSGLIRTPERAEAVLVVACVE -GELSLAKAERTLRQVGEAL---- ->[subseq from] Beta-lactamase n=3 Tax=Bacteroidales TaxID=171549 RepID=A0A3N2KX94_9BACT ----MADSITKIVDDYPGEIGVAVI-INNTDTI-TVNNENIYPMMSVFKTHQALAVCDDLD -NKGISLDSLMTIQRDELDAWSPMLKEHHENVLPVRDLLRYALSQSDNNASNLMFKKLVDV -AATDCFIATIPRSSFKIAYTEEEMSADHDKAYANSTSPLGAAILMNRLFTDSLVSHEKQS -FITATLKECVTGVDRISAPLKAGVTIGHKTGSGYTNAHNDVAYISLPDNTCYSLAVFVKD -FKGNESEAAKAIARISATVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. 2017 TaxID=2169540 RepID=A0A2S1H398_9BACI ------EIIQQFIENSSYKIHTVVQDYETDEVLvHIRADEVFSSASVIKVPILIAILHHLQ -QKGGDLQQVLTIASENVVEFSVITEQQ-QTSATLYELLTWMIITSDNTATNECIDFL-GM -DEFNRYFKEIGLSNTVVQRKMMDFERQ-QLGLDNETSARDMQHLFKLIYEGKLLEPKWND -IAIDILCRQRS-QDSLKRYLLEPVKMAHKTGGLDT-VDHDVGIVYTDGT-AYFIGVFITE -VTNN-EKAKQEIGLISKMVYEH- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VMA3_9BACT --dKLRSRIETVDRGLDGVLGLSVKDLKGGMTL-EIRPQEPFPQASSIKLAVLYELFRQAE -EGRVDLRE-LTRPPLPRVRGGGVLQELGDRLLTWRDLAVLMMGWSDNAATNVLIDRV-GM -EAVNRRLDSLGLRATRLRRKMMDLEAARRG-DENVSTPAEMRQLAEAMYAGAGLSKERVK -DLLAVMAVPKD--SPFRVPLPEDLVVADKPGTLE-AVRCVTAIVDLPGR-PYAVSIMTTY -LRHD-ADGEAAIKQISSALYETf ->[subseq from] Uncharacterized protein n=1 Tax=Salinibacter sp. 10B TaxID=1923971 RepID=A0A2P6C2C1_9BACT ------QHIRPLLESIDGECAVAVRSLESSEEV-LLDANVEFHAASTMKVPVMVELYRQAA -NGQFSLDDSIRVENESIVDESPYAYEHLGDRRSIRTLMRVMITASSNLATNLLLEVV-GP -EKVTRTMHRLGAEGLQVRRGVEDSK-AFRRNRNNTTTAHGLLVLFEHIARGTAVSEEASA -EMINILKAQEH-TEMIPARLPDTVEVAHKTGWIT-GVRHDAGIVFVPEGPTYVLVLLSRN -LS-DVPAGVETLSRISRVVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7S127_9BACT ---ALRQRIDAAARKSDARIAVALHDAESGAEL-HYDADRWFHGASTIKIAILLAVYGEID -RGRLAPQSRLHVRNRFLSAGSPFRHASIGKTMRVSELALHMIAMSSNLATNLLLDLI-GL -ETVQRTIERFGLTGLDIRRGVEDE-KAFEHDIVNRVTANGLVGLLRLIAEERAYSPELSR -EMLDILHQQEF-KKGIPARLPRDVRVAHKTGDISS-VAHDAGVVYAPGRKPYVVAILTEW -AA-DAGSRSPTIASISHAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Acidovorax valerianellae TaxID=187868 RepID=UPI001113FE94 ------------------------------------------------------------- -----------------------------------------------------------GP -KRLQALARSLDVAAGALNKTLDEAYDRYYRHQANTATLEGYGAMLEKLVRGQLVSPAHQQ -LLYKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQFH-RACHMGVIDPQNGRRAIVVAACAE -GLDEMKEAGKAFEQIGRAITQ-- ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-105 (HZI) TaxID=2486472 RepID=A0A3N2MN95_9BACT ----MTSLLKDFAAGKDARIGIAVI-INGRDTV-SVNGHRDFPMLSVYKFPQAIAVADYCV -RHGISSADTVAVGHEEILAWSPMRDRYGIRDLPLSELLAYSLQQSDNNACDILFRLIGGP -QAADSLMNTLGFDDIVMASTEEEMHGDTYLCYQNRSTPLAMARLFDRLYRQGMRSESALE -TIATMMIQCATGLNRLPAPMATNAMIGHKTGTGDRNGINDAGYVFLPDGNGYSIAVFIAD -SAYDMAATEQLIAEISTIVFN-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537KJX7_9BACT -------------SSQKGIFAVAFKEVATGKDL-LINEKEVFHAASTMKTPVMIEVFRQAA -RKKFSLNDSITLKNESIVDSSSYSYKHIGEKRSIHDLVYQMIIASSNFATNLIIEKV-GA -KNVTETMRHYGAKDIQVLRGVEDQK-AYDKGLNNTTTAYDLMLIFEKISKGKAVNRKASK -AMIDILLDQKF-NTIIPAQLPKDVKVAHKTGFIT-GIHHDSGIVFLPDGRKYVLVLLSKN -VE-DEAATIKAMANVSGMIYQ-- ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T051_9BACT --tALQNELTDFVKDKDARIGMAVI-IDGKDTV-AVNGKEDFPMLSVYKLPIALALADNYR -VKGLDFSEPIAIAKEDLHLYSPMTGRLLASSMPTREILNYMLQQSDNNASYLAVKKLGGT -ENVMKWLSKSGLSGVKVVSTENEMHINPELSYKNSSTPIAMARLLDKLDTE--WNDSLSK -EIKQMMETCKTGENRLAKLLPTNAVTGHKTGTGFIMAVNDVGYVHLSNGHRYSIAVFIAD -AHYDMAESENIIAQISEMVWR-- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=E4PXX3_STAAU ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKK--- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Niastella caeni TaxID=2569763 RepID=A0A4S8I3N1_9BACT --nKLQDQISSRLAEQPGDFAVAFKDLTTGDTL-LINDQAFFHAASTMKTPVMIEVYKQAA -AGTFTLNDSFVLKNESIVDSSVFSYRHLGEKRTLYNLVYDMIIKSSNLATNMVIELV-NA -RNVTQTMRQLGAKRIQVLRGVEDSK-AYEKGFNNVTTAHDLMVIFEKMAKGEIVDSASSQ -AMINILLNQQF-KEIIPARLPRDVKVAHKTGNISH-VQHDSGIVFLPNGRKYVLVLLSKN -LQK-EEQAIKAMADVSEMIYNY- ->[subseq from] serine hydrolase n=1 Tax=Aquincola tertiaricarbonis TaxID=391953 RepID=UPI0012ECFFFA ------------------------------------------------------------- -----------------------------------------------------------GP -QRVTALRRTLGVQASELQPTLEEAYERYYRRGLNSATLEAYGGMLEKFVKGELVSPQHQQ -VLFIDMKFDRYDNYRLEAGLPRTVKFIHKTGTQFQ-RACHMGVIHPQDGRNAIVVATCAE -GLDENKLAGQMFEQIGRAITQ-- ->[subseq from] Beta-lactamase n=4 Tax=Bacteroidales TaxID=171549 RepID=E5WU37_9BACE -----TDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium oral taxon 876 str. F0540 TaxID=1321778 RepID=U2ERJ0_9FIRM ------KEIKRYIDTRIGDYSFYFEDIDSGYSY-SLNEKAIMPSASCIKVPIAMALLKEVE -NGSINLDHKVFVNKEEMVEGSGIIHELDEKDYSIRELLAAMLIQSDNTATNKIIDSL-GM -DKINNYIKQMGLKDTLLKRKMMDLKAR-ERGLENITSSLDLANCFKELHNGNYLSKNSRE -YIVTILRKSQN-RDKLPFYMPREWKIANKTGSLS-GIENDAALINIDKGN-FVFVVMAKS -LPN-NIYGIVTISRVGKMMWD-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Leptolyngbya antarctica TaxID=268115 RepID=A0A2W4VVN8_9CYAN -----RGELEQLSTLTPGTPVAFAIDLDSGQYV-DLGGAEPVAAASTIKVPILIAFLQQVD -AGTMALNQSLVLQEDSMAGGSGTLREAVGTEYTALDIATRMIVVSDNTATNMMIAALGGV -EALNQTFVTWGLEHTVLRNPLPDIEGT------NTTSAKDLALIMALIDQGGLLMPRSRD -RLFSIMQRTQN-DSLIPSGIRDQSLTANKTGDIG-GMLGDVALVDVPNGKRYGLAVLVQR -PSND-GRASELIRRMTETI---- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus simplex TaxID=1478 RepID=A0A120GMN1_9BACI ----IENDIWALVDAFDGNIAYKIES-GFGDMI-GYQEEDSFQSASLIKIPMIIEGYRQSE -RKNIYLNQPVTIPPNAVTGGSGVLHALSNKVLTVEDLLTLMITVSDNTATNMMMSLL-GI -DEINRCIQELGLKNTILGRKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTEN -M-KSEEESRQVISKIGKLIYDH- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H8U6_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVRRALNLKTADLQRTMDEAYERYYARKLNSATLDGYGALLEKLVRGQLLSPAGTR -RMFEDMKLGIFTNYRLQAGLPRDVPFIHKTGTQHR-TACHAGVIDPEDGADAIVAVTCAA -DVDEQHEAGRIFERVGEAIT--- ->[subseq from] serine hydrolase n=1 Tax=Rufibacter sp. DG31D TaxID=1379910 RepID=UPI000664784A --qKTEQELRGILEKSSALTGLVAIDLTSGEAF-RFNQDLVFPQASAIKVPILLEVYKQAQ -AGKFALTDVRRIAPGQVVGGTGIIKDLEDSTFSIRNLAVLMIALSDNTATNALLDLV-GL -SNINASLQAMGLKQTRVQRKMIQAAAS-GRGEENISTPAEAAKILQMLYKGEFLNKATSE -EIISILKKTNRETSRLAPGLPDHVPLAFKPGILN-GVSTEWALVLLPER-PYAVAIMENF -K--PMGQDGMVLEDVSKVLYQYf ->[subseq from] serine hydrolase n=1 Tax=Thermobaculum terrenum TaxID=166501 RepID=UPI0009FF52AC ----LQERIANIIDSV-GYFGVAAKDLTQGREL-FINADETFNTASVIKVPIMIELFRRVY -EDNVSLDDRLILEDRFRTGGSGILKEFRSGLLTLWDLCVAMIALSDNVATNMLIDYL-GI -DAINRCMDSLGAHNTRLHRMV-GFKSIKPDQPKGRTTPRDMMMIFQKLAEGNVISESASE -EMIAILAKQHD-RNMIPRLLPDSAIVANKTGAVD-GVRNDVALIRFADGRQWVICILTKD -LRKVDHEGEIAIAKIALEIYKEw ->[subseq from] Beta-lactamase n=1 Tax=Prevotella buccae TaxID=28126 RepID=Q8KT59_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFVATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. TH156 TaxID=2067454 RepID=A0A2N4X7H9_9BACT -------KLNDYLRQLPATIKVSMVSVTGHRYF-AYRPEAIVPAASVIKIPVLIELMDQAG -KQKIELTKIYKLTAADKTGGSGIIAGMPDGKFTLRELAQEMIHSSDNTATNVLIREV-GM -KAINDNLIRLGSTHTRLNRIMMDTLAA-RQGRENYVNAVEINDLLRKIYNNNIATPALCK -EMLEILKNCAD-TTTIPRYLPRQVAIAHKTGELSY-VRGDAGIVYT--GNPFILSVFVEG -FD-EMSQAEKIIGDLALICWE-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JK35_9BACT ---AVRHQIEKIEKESGAKIAVALHDSETGFEI-HYHADRWFHAASTIKVPILLGVFAAID -RGELLPHSRVHVRNRFLSVDIPFRHNAIGKMMRVDELAYHMITTSSNLATNLLLGVI-GP -ASVNETLRELHDDGIELKRGVEDEL-AFEKGINNMVTANGLLRILVMLADGKAFSPALSR -RMMDILHGQEF-NQGIPARLPKGARVAHKTGEIST-VAHDAGVVYLPKRKPYSLVILTEW -DP-SATARSRTIAAISQTIYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chryseolinea serpens TaxID=947013 RepID=A0A1M5TZ58_9BACT -hdKVKETITQALAGQQGTFAVAFKDLSTGEEL-FINEHMPFHAASTMKTPVMIEVFKQAA -EGKFSLTDSILIKNESIVDGSPYHYRQVGKKRTLQSLVYEMITVSSNLATNIVIEWV-DA -KKVTQTMHDLGAKDIQVLRGVEDDK-AFEQKLNNSVTAYDLMLIFEKLAKGEAVNPEASK -AMIAILLDQKY-NDIIPAKLPRDVKVAHKTGWIK-GLHHDSALVMLPDGRQYVLVLLSKD -LK-DEKAAVEALNDVSKTLYDY- ->[subseq from] Serine hydrolase n=2 Tax=Terrimonas sp. NS-102 TaxID=2171976 RepID=A0A2T7Q797_9BACT ---ALREKISNIFSQFEATFGVAFKNLNTSATF-FWNAEDIFHSASTMKTPVMIEVYKQAA -QGKFSVTDSMLVKNSSIVDGSTYSYLHIGKKLPIRDIVFRMITVSSNLATNNIIELV-GA -KNVTATMRKLGTKNMQVLRGVEDKK-AFEKGLNNITTAYDLVLVMESIAKGTVADKRSTD -DMLDILLHQRF-KRVIGGKLPADVKVANKTGAFK-GVRHDSGIVFLPDGRKYVIVLLSRG -IE-DDEKSAAALAEVSRLVYEE- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella oralis TaxID=28134 RepID=Q8KT51_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KANNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLVTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma rigui TaxID=564064 RepID=UPI0009AF998B ----------------GVRVNLAVQSLADSSESfVQGATDQVPSASVIKLPIMIEAMEQVK -AGRLDLDEIHILTDGEKVGGDGVLKTYSHRSVAYRDLLRLMMIYSDNTATNIFINEL-GM -DAINRRIQALGLSGSQLNRVMMDTLAV-RQGRENYVTARDMNRLLGKLYRNEVATPELCA -HMIAILKQNED-MATIPKRLPAGTVVAHKTGTLAY-IRGDAAIVYA--REPFLLSIFVAG -VP--TPQAEQLIADISLICYTHf ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TP62_9ACTN ------GQLQQVVDASTANAGVAVRDLSGDQQI-ALNGAFRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPSQVVDGTGELQHETFPQVTLYRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWEAQILTPATRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG -PM---AGGDETVRRLARTVYDY- ->[subseq from] Beta-lactamase n=5 Tax=Bacteroides TaxID=816 RepID=C6Z584_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=2 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JQ71_9ACTN ----LTERLRAIVAASPNPTGVAVRDLSGDQQI-GVNGTFRPKAASVIKLWILTELLREVD -CGWQRLDDGVLVEPKDVVGGSGQLQYETFPQVTLYRLARYMIIYSDNTAANVLINHLNGF -VRVNALIDTMLLKQTALNRRMLDTAAA-ARGEENYLTADDVVSLLGAVWDGNLLSPVSRT -LMISFMLEQTI-NTKIPAALPPGVPVAHKTGELPD-ASHDVGYLLIPHSE-VAVAFVTSG -PE---ATGAETVRQLARAVYDY- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=unclassified Prevotellaceae TaxID=224765 RepID=UPI00094E1C15 ----LTDSISQIVSACPGEIGVAVI-FNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pontibacter chinhatensis TaxID=1436961 RepID=A0A1I2RFE8_9BACT --qQTENQLAAIINRSPAVTGLVAVDLTTGDTF-SFNAGVVFPQASAIKIPVLMSVYKQAH -EGKFSLTDIRQVAAADVVGGTGVLKDLDGPPMSIRNLGILMITLSDNTATNALIDLV-SM -QETNAMLRALGAKHTLLQRRMINAAAS-GRGEENISTPADAAKILQLLYKGEFINKAASE -EIVSILSKTDRQTSRLAPGLPDNVPIAFKPGILN-GVSTEWAIVLLPER-PYAVAVMESY -KV--KGQAEHTIEDLSEVLYQYf ->[subseq from] serine hydrolase n=1 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=UPI0004B6B941 ----LRQKIEAIEARSPKALAVAMRDLGTGLTF-DHHADRWFHAASTIKVGILLGVYGAIH -EGRLVAQSRVHVRNRFSSAGSPFRHQHIGSTMRVSELALHMIATSSNLATNLLLDLV-GL -DTVQRCLESLHIHGVDVRRGVED-ERAFEHHVNNRVTADGLAALLRAIAEERAFSPEISR -QMVDVLHAQEF-KSGIPARLPKAVRVAHKTGEIST-VAHDAGIVYPPDCPPYVLVVLTEW -EP-DGTGRSATIAEVSRAIYE-- ->[subseq from] serine hydrolase n=1 Tax=Larkinella terrae TaxID=2025311 RepID=UPI0012AD9868 --eQLKQQIELEFKKQPGRFAVAFKDLTNGREL-LIREQEVFHAASTMKTPVMVEVYKQVA -QKRFSLTDSVLIKNQSIADGSLYSYTEVGKKRTLYSLMYDMIIVSSNLATNLIIDLV-DA -TKVTQTMRELGAKNSNVLRGVEDTK-AFQKGLNNTVTAYDLMVLFEKIATGKAVSSQASE -AMIKVLLDQHF-SSVIPAKLPNDVKVAHKSGSFAT-VRHDSGIVYLPDGRKYVIVLLSKE -MP-DDAAATETLATVSGLIYQY- ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter mishustinae TaxID=270918 RepID=A0A0Q9ZAZ2_9FLAO --kELQNKIASIFEENQGEFAIAFKNISEEKDSiLINAHENFHAASTMKTPVMIEVFKQAS -EGKFSLQDSLVIKNESILDGSSYSYEQIGQKRSIEDLVTDMIIYSSNLATNIIIELV-DA -KNVNQTMREMGAMDINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALAKGKAVNAEADK -EMLHILQQQKH-TDLIPALLPENLKIANKTGWIT-GVHHDSALIELPDGKKYVLVLLSKN -MK-DMEAGTKMLSEVSKLIYDH- ->[subseq from] Serine hydrolase n=1 Tax=Luteimonas sp. XBU10 TaxID=1132694 RepID=A0A5D4XUQ7_9GAMM --qELQRRLAAADARYPGDLGVYVRHLERDESF-SYLAEEPWYLASGIKVPVAIAVLRAVA -RGELALDARITLREDDFVDGAGATNSVRAGSLRVSWLLEQMIVHSDNTASDVLIRSV-GI -DAVNAVAAELTDTAGVRITTLADVRRAYYATHVNSASLVDFGRMLAALAEGHALPARETA -YLLDLMARVQTGKRRIRAGLPPGTRFEHKTGTQHR-RSCDLGIATVPGSARVVIAACARG -TG--TAAAERALRDVGAAVT--- ->[subseq from] Beta-lactamase n=4 Tax=Bacteroidales TaxID=171549 RepID=Q5UAF8_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGCNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Prevotella melaninogenica TaxID=28132 RepID=Q5XLF9_9BACT ----LTVSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=2 Tax=Pyrinomonas methylaliphatogenes TaxID=454194 RepID=A0A0B6X2N0_9BACT --kALDQRVRAEISKFKGHVSLFAKNLDTGASY-GFGADDRVRTASTIKVPIMVEVFARVA -EGKAKWDDELVLTEAKKVSGSGILLELSDGLLTLRDAVRLMIILSDNTATNLILDQI-TT -DAVNDRMDQLGLKQTRVLRKVGGGGEMIPENKRGVSTPREMVALLEKLERGEVVNTEASR -EMLAIMKRQQY-RDGIPRALR-GVEVANKTGALDR-LRSDVGIVYTPRGR-IAMAITCDD -M---------------------- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella melaninogenica TaxID=28132 RepID=Q8KT52_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTFKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Variovorax boronicumulans TaxID=436515 RepID=UPI0011A6F74D ------------------------------------------------------------- ------------------------------------------------------------P -QRAEAVRRALALPAGALRSTIDEAYADYYAEGRNSATLVGYGAMLERLVRGDLLSPASTE -RLFQAMKFGTRGSYRLEAGLPEHLRLIHKTGTQHQ-RACHMGVVQPQDGDATVIAVCAAE -LD-EQRAAGRLFEAVGRAIA--- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. ICM33 TaxID=1161412 RepID=X6Q3X8_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5Y7E9_9BACT ----LNEELERLNDQSKARIAVAVHDLESGWRF-SLRADRWFHAASTIKVALLLAVFRAAD -ESRLRLDDSLHVRNRFFSAGSPFHYQAIGRTAKISALAEGMISSSSNLATNLLLDLV-GV -EYARKVLRDAQVDGVELRRGVED-HAAHQREINNEVTADGLVRLLSAV-RGDFLSKESKE -QAIRILLDQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -AS-EQDGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase (Penicillinase)-like protein n=1 Tax=Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310) TaxID=365046 RepID=F5XZA2_RAMTT ---RLPAELAAVDARHRGQIGVHVRDLQTGVRV-NHHADQDWYIASMVKVPVAIAVLRGVE -AGLFTLDTPLRLRAADYVDGAGATNGHPVATLPIRFLMEQMIIHSDNTASDMLIELV-GL -PQVNALVRSLVPQGFGRITTLAEVRRAYYAGGLNSARLDAYGQLLALLAQGGALGPDATA -YLLGLMERVATGPNRIRAGLPADARFAHKTGTQRQ-RVCDAGLVRMPGAGAGAVVVACVR -GEASLARSEAALRDVGEALC--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9XRX0_9ACTN ------GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD -CGQVSLEDGVLVTPSQVVNGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG -PM---AGGDETVRRLARTVYDY- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Prevotella pectinovora TaxID=1602169 RepID=UPI0005B7274F ----LTDSISQIVSACPGEIGVAVI-FYNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013B36BB1 ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAALLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDRTEPT------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. M6-12 TaxID=2054166 RepID=A0A2N5I2K8_9BACI ----LEKAVKIEIEKCSGRVGLYLEL--DGGTI-EHNSNEVFRSASLIKVPILVEGFRQKE -EGRIHLNQPVTIQRRDKVGGSGVLQVLSDKSMTLKDIMTLMIIVSDNTATNVMIDLL-GM -DSINRTIKELGLEKTILERKMMDFQAA-EQGKDNLTCAADMALCLKAIQEASFLSDESSR -EMADILKNQQF-LDKLPAMMDDKVAVAGKTGGLHC-IEHDCAIIRYGEK--VAYAAVLSD -ELPSKEDGRRTISAIGKLIFD-- ->[subseq from] Serine hydrolase n=1 Tax=Flavobacteriaceae bacterium TaxID=1871037 RepID=A0A2E1RIV5_9FLAO --dSLEERIVGLLDSEKGEFAVAYKNLSTGETI-LINENEEFHAASTMKTPVMIEAFKKNN -EGLISLDDSILIKNESIVDGSIFKYEKIGSYLTLKELIYDMITISSNFATNLVIDYI-GT -KEINNTMRSLGANNINVLRGVEDIKA-FNNGMNNTTTAHDLLKIYENLAKGNIISSDISD -EMINILKNQKY-DDIIPKYLPKSVEVAHKDGWIS-GVRHDSGIIFLENNKKYVLVLLSKK -LEN-EIEGADILAKISLEIYN-- ->[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium RA TaxID=1779382 RepID=UPI0012D35464 ------------------------RDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE -AGRFSLDDSLLVRNTSIVDGSTYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA -DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLFDALRRGAAVSPEADR -AMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG -ID-DRARSAELVAEVARAVHQ-- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3Q3K9_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -RRVQALARALDVPQKSLQQTMEDAYARFYRRGDNTASLVAYGGLLENLVRGKLLNAEHQQ -LLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQFQ-RACHMGVIDPQDGQRAIIVATCAE -GLDEQKQAGRAFESLGRAITQ-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella oralis TaxID=28134 RepID=Q8KT50_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSRFQIAYTEEEMRADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=A0A379JJ68_9NOCA ----AETRIRAVFADAGCTGWLHARRCDSGTEI-SLGGDERVVVASVYKLPLFVAFCRHID -AGRVDPTARITVTPSDCTPPTGIAALRDPVTMSLRDLAASMMTVSDNAAADVLLGAI-GL -AAVEELLDDLGLTRTRIIGGTADLHRAYDPSYTSATTPEEMTRFLHALWRGDILSPERTD -YARAVMRAQVW-QHRIAAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPAVDAAIAEVARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RL99_9BACT ----LRQKIEAIEARSPKALAVAMRDLGTGLTF-DHHADRWFHAASTIKVGILLGVYGAIH -EGRLVAQSRVHVRNRFSSAGSPFRHQHIGSTMRVSELALHMIATSSNLATNLLLDLV-GL -DTVQRCLESLHIHGVDVRRGVED-ERAFEHHVNNRVTADGLAALLRAIAEERAFSPEISR -QMVDVLHAQEF-KSGIPARLPKAVRVAHKTGEIST-VAHDAGIVYPPDCPPYVLVVLTEW -EP-DGTGRSATIAEVSRAIYE-- ->[subseq from] serine hydrolase n=1 Tax=Ramlibacter tataouinensis TaxID=94132 RepID=UPI0009D9B371 ---RLPAELAAVDARHRGQIGVHVRDLQTGVRV-NHHADQDWYIASMVKVPVAIAVLRGVE -AGLFTLDTPLRLRAADYVDGAGATNGHPVATLPIRFLMEQMIIHSDNTASDMLIELV-GL -PQVNALVRSLVPQGFGRITTLAEVRRAYYAGGLNSARLDAYGQLLALLAQGGALGPDATA -YLLGLMERVATGPNRIRAGLPADARFAHKTGTQRQ-RVCDAGLVRMPGAGAGAVVVACVR -GEASLARSEAALRDVGEALC--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5PG77_9BACT ----LNEELERLNDQSKARIAVAVHDLESGWRF-SLRADRWFHAASTIKVALLLAVFRAAD -ESRLRLDDSLHVRNRFFSAGSPFHYESIGRTAKISALAEGMISSSSNLATNLLLDLV-GV -EYARKVLRDAQVDGVELRRGVED-HAAHEREINNEVTADGLVRLLSAV-RGDFLSKESKE -QAIRILLEQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -AS-EQDGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=R7LIT6_9CLOT ------SSLRNLSAMYSIHPSIYVWDYETGNYA-DVNANEIFPTASIIKLPVLVQLFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYTIDTLARMMITESDNSATNMIMARLGSM -TDINQGIREWGLKHTYVQTWLPDLGGT------NHSTARDMATILYNIDNPKFLSTSSRE -KIFDYMGHVHN-NRLIAAGLPAGAEFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR -PHN-SPLGKEFIVKASEIIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus thermocopriae TaxID=1215031 RepID=A0A6B3TMH9_9BACI ----WKEKITKELVDFKGRVGVAIEI--ENERY-EFHSEEVFPSASVIKVPILMECLKQSE -HGNIDVDEFIKITE--RTGGSGVIQALSTNLLTIKDLMTLMITVSDNTATNMLIDFV-GM -DPINRTMEELELHTTRLQRKMMDFAAK-EKGLDNVTSPSDMVKCLKIIHEGDFLSANSRR -MALDILHFQQFHDKLLAMIDTDKVFTANKTGSLPN-VENDCAILKVGSKT-AYVAILTDK -LS-DPYEARQVISRIGKHIYH-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1) TaxID=929705 RepID=A0A1W1WGQ0_SULTA -------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE -EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV -DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE -QMVNLLTRCQVSIAKIPADSVKEVIIAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A661XVV8_9BACT ---QLSKDLSEIITDSQGTYAVAFADLKTGDTL-FINGHESFHAASTMKVPVMIELYKQAQ -EAKFSLDDSILVKTESIVDGSLYTYEKVDSMLPIRELMYHMITKSSNLATNILIELV-DA -KKVTATMRDLGAPDIEVLRGVEDLKA-FDSGLSNSTTAYDLMKILEAIGMEKIINEEACG -EMMNVMFDQQF-NKIIPSQLPSEVKVAHKTGSIT-GVQHDAGIIVLPTGHKYVLVLLSKE -LE-DKDKGVETLSLISKKVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium halophilum TaxID=1416801 RepID=A0A1H7BK67_9BACT ---ALEEEIRSLMQATEGDFGLAFRMLDTDREL-LINESEVFHAASTMKTPVMIELYKQAA -AGEFDLQDSIRIVNESIVDGSSFRYERIGEKATIYELMYQMIIKSSNLATNILIDRV-DA -KNVTQTMRDLGAEDIQVLRGVEDLKA-FDAGLSNTTTALDMMRIMEAIALGKV---EGSA -EMVQILSDQYF-KDLIPKLLPPDVKIAHKTGSIT-GVQHDTAILELPGGSRYVLVILSKN -LS-DVPAGKEAIARMSRVIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium RBG_19FT_COMBO_52_11 TaxID=1797852 RepID=A0A1F9DSF3_9DELT ------------------------------------------------------------- --------------------------------LSVQNLLELMLLISDNSATDLLLRLAGGP -EAVTARMRALGIRDMEINRPTIHLIAKFEADPRDTSTPEAMVMLLERIFRGDLLKRESGA -LLLDMMKRCRTGKARLKGILPAETVVAHKTGSLG-GTTNDVGIIALPDGGHIAIAVFVKS -SEKEIQERERAIAQIARAVYDFf ->[subseq from] serine hydrolase n=1 Tax=Bacillus psychrosaccharolyticus TaxID=1407 RepID=UPI00031EA407 ---TIEKDIIELVQLFDGRISYKIEK--DEQVI-EYNSHDIYQSASLIKIPMLVEGFRQVE -KNKIAFTQHVPFIQGDVAGGSGVLSALSNSLLTVKDLLVLMTIVSDNTATNMLISLL-GM -ENFNTCMDDLGMKDTMLQRRMMDFQAA-ADGRENITTAADIVTCLKAIHKGDELLSSSRQ -QILEIMEKQQF-CDKLPAMMGNEVKIANKTGSLD-GVSHDAAIIRYGSET-VYAAILTDQ -IS-SSEESRQLISQIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI000A053672 -------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE -EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV -DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE -QMVNLLTRCQVSIAKIPADSVKEVIIAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Roseicyclus mahoneyensis TaxID=164332 RepID=A0A316GX55_9RHOB --------LELIEISAGTDISVALLDTASARSV-QWNDTARINLDGTVSLLLAAAVLRRVA -EGRDVLDRDV-----------PAAEGLIGQKMTVDALCAAMMTRGDSTAASLVLGVVGGS -DGLTSFLRDIGDVETEVAATAAQGDDATPGSIRGTTTPCQMLRNLERLLLGDGLTADGKA -RLLDWKTSNTTGASRLRAGSPEGWIVADVTGQGAYGETSALAAIFPPDRTPLLMAVYFGR -SPRAPGAQDRYFAELARIATD-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Calditrichales bacterium TaxID=2528038 RepID=A0A524LC39_9BACT -------------------VAVSFQTADQDQYM-GINDTLSMHAASTMKVPVMMEVFRQVQ -AGKFSLSDSIVIKNESIIDGSLYSYAMIGKKESIRSLVHEMITYSGNLATNLLIGWV-QP -ENVQNLMKQIGANDIQVLRGVEDIKA-FEAGKSNTTTAKDLAIIYQDIYNGSEWTESSRK -EMIDILLDQKF-NKKIPAGLPKEVKVAHKTGSITE-IDHDSGIIYPPQTAPYILVVLTKG -FKE-HERAQETIAEISRRIYAWy ->[subseq from] Beta-lactamase class A n=1 Tax=Falsibacillus pallidus TaxID=493781 RepID=A0A370GP18_9BACI ---RLRDEITQLASVCPGRIGLAIE-THEGKIL--LNEMDRFPSASLIKLPILIECFRQVE -AGKISLDEPVDFSSLKRVGGAGVLPALSDSVLTVKDFMTLMIIVSDNTATNFLIDLA-GE -KEINDCIKTLQLKETSLGRRMMDFE-AIRNGKNNYTSPEDMLLVLKEIDRGKLLNKKSRE -LILQIMKQQQF-VDKLPALMDTEVTAANKTGELD-GVEHDCGIFTYGEK-TVYASVLIDG -LY-DKELGRKTISRIGKAIFDY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A649UHW1_PSEAI ------------------------------------------------------------- ----------------------------------------------------------GGP -AGLTAFMRSIGDTTFRLDRWELELNSAIPGDARDTSSPRAVTESLQKLTLGSALAAPQRQ -QFVDWLKGNTTGNHRIRAAVPADWAVADKTGTCGYCTANDYAVVWPTGRAPIVLAVYTRA -PNKDDKHSEAVIAAAARL----- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=UPI0011C3A55F ------GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD -CGQVSLEDGVLVTPSQVVNGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG -PM---AGGDETVRRLARTVYDY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=UPI0011C35583 ------GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD -CGQVSLEDGVLVTPSQVVNGTGELQHETFPQVTLHRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG -PM---AGGDETVRRLARTVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A327J8K0_9BACT ----LEDGLKELMKKYTIQPAITVWDFNTGKYV-DINGSEIYPAASIIKVPVLINLFKTIE -ANGLSIYDEMTLTNYYKASGSGNLQYAASGKYTIDKLAKTMIEDSDNSATNMLMSKLGSM -TAVNTAIRSWGIPNTHVQTWLPDLTGT------NFTTTNDMATMLFNLDNPNFLSINSRE -YIVDYMSHVKN-DRLIPQGLGKGATFLHKTGDIGT-MLGDAGIVYMPNGKKYIVVIMAKR -PYN-SPLGKQFIQQASKLIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UP67_9BACT --dKLRSRIETVDRGLDGVLGLSVKDLKGGMTL-EIRPQEPFPQASSIKLAVLYELFRQAE -EGRVDLRE-LTRPPLPRVRGGGVLQELGDRLLTWRDLAVLMMGWSDNAATNVLIDRV-GM -EAVNRRLDSLGLRATRLRRKMMDLEAARRG-DENVSTPAEMRQLAEAMYAGAGLSKERVK -DLLAVMAVPKD--SPFRVPLPEDLVVADKPGSLE-AVRCVTAIVDLPGR-PYAVSIMTTY -LRHD-ADGEAAIKQISSALYETf ->[subseq from] Beta-lactamase n=1 Tax=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) TaxID=700598 RepID=G8TLL8_NIAKG --nKLKDQINSRLAEQPGNFAVAFKDLSTGDSL-LINEQDFFHAASTMKTPVMIEVYKQAA -ARRFSLNDSVVLKNESIVDSSLFSYQHLGEKMPLYNLVYDMIIRSSNLATNTVIQMV-NA -RNVTLTMRQLGANKIQVLRGVEDSK-AFDRGLNNVTTANDLMVIYEKMAKGEIVDSASSQ -AMIKILLDQEF-NEIIPARLPKDVKVAHKTGNITH-VLHDSGIVFLPNGKKYVLVILSKN -LQN-EANAKKAMAEVSEMIYRY- ->[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera acidiphila (strain ATCC BAA-1392 / DSM 18658 / VKM B-2454 / MOB10) TaxID=886293 RepID=L0DQE0_SINAD ---TLESRLKPLIQAHKGKVSVAIKNLETGESF-LYHEDDPMPTASLIKLPIMIESYRQAE -EKKIDLGEMLTLKQSDKVPGSGILTDHFSAGFPLVDAIHLMIVYSDNTATNLVLDKI-GI -GSTAAFMEKLGYPNTKAHSKVFRRDTRSKKFGLGSTTAAEMIRLCESLQKGELVSKEASE -AMLKHLRACDD-KDKFPRFLPPDTKIAFKTGSVDS-SKTAAGIIECGQG-PVAVCVMTDE -NEDKDNAGNRLCAEVARVVFEHf ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 TaxID=1798438 RepID=A0A1G0SSS3_9BACT --nDLLRDLDSLCAESGGAVSIAAEHLDTGERI-LISENDMYHAASTMKTPVMIEVFRQAA -EGKFRLDDSIVVRNDSIVDGSPYSYNLIGKPATILFLIRHMITVSSNLATNILIELV-DA -RKVTETMRTLGAKDMNVLRGVEDGK-AFQKGLNNETNAIDLMTIFKAIAEGKAVGAEEDK -AMVDMLLAQRF-RSKIPALLPEGVRVAHKTGNIT-GVEHDSGIVFLPDGTQYVVVILMSK -LKEN-ATGVRAAAKISRRIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A350BIN3_9BACT --nDLLRDLDSLCAESGGAVSIAAEHLDTGERI-LISENDMYHAASTMKTPVMIEVFRQAA -EGKFRLDDSIVVRNDSIVDGSPYSYNLIGKPATILFLIRHMITVSSNLATNILIELV-DA -RKVTETMRTLGAKDMNVLRGVEDGK-AFQKGLNNETNAIDLMTIFKAIAEGKAVGAEEDK -AMVDMLLAQRF-RSKIPALLPEGVRVAHKTGNIT-GVEHDSGIVFLPDGTQYVVVILMSK -LKEN-ATGVRAAAKISRRIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GXN5_9BACT ---SLKETITARLKTVEGEFAVAFKDLQTQETF-FINERENFHAASTMKTPVMIEVFKQAK -AKKFKLTDSILVKNESIVDGSPFKYRQIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KNANATMRQLGAKEIQVLRGVEDTK-AFQKGLNNSVTAYDLMLIFEKIALKKVVNRKACD -EMIRILFDQKF-NEIIPAQLPGIVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLILLSKK -LVKP-KEGVRALADISRLIYE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Prevotella intermedia TaxID=28131 RepID=Q5XLF8_PREIN ----LTVSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A346QRV4_ECOLX ------------------------------------------------------------- ----------------------------------------------DNSASNMMLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQ------------- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A5M5C6X4_BACOV ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVAYS-- ->[subseq from] Serine hydrolase n=1 Tax=Pontibacter actiniarum TaxID=323450 RepID=A0A1X9YTN2_9BACT --qKAEEQLKDIIGRSPAVTGLVAVDLTSGETF-AFNADVAFPQASAIKVPILMSVYKQAH -EGKFLLSDQRKVAPGNIVGGTGILKDLVDTALSIRNLGVLMIALSDNSATNSLIDLV-GM -PEVNAMLRSLGAKQTLVQRKMINSAA-SGRGEENLSTPADAAKILQLLYRGEFINKATSG -EIVSILRKTDRRTSRLATGLPDEVPIAFKPGELN-GVSTEWALVLLPER-PYAVAVMESY -KV--EGQGEETVEELSEVLYDYf ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea indica TaxID=1581193 RepID=UPI000C79E95A -------DFAAVFRAAGVTGYLHALDIDSGKEL-GHGSDEPMPTASVFKVPLMVAFCRQAD -AGLLDPGERVTVRAAERVFPTGVSAMLDDVTMSLRDLAYLMIAVSDNTAADVLLHRV-GL -DAVNAMLTTFGLRVTHVQQSIADFYRVLDPWHTNRSTPREMAALLSLIWRDEAASPASCA -WMRAVLNKQVW-PHRLASGFPDDVDVSGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRS -FSVNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Cystobacter fuscus TaxID=43 RepID=UPI0012DFCE9D ------------------------------DAL-YLEADRSFHAASTMKVPVMLEVFRQVD -AGTLSLEEPVTLTRESIVDGSPYVHERLGQSVPLRELVERMITRSSNLATNLVLSRV-DA -RRVTKTLRALGARRMTVLRGVEDGK-AYAQGLNNTATARDLASLLSALERGRAASPASTR -AMRSILLAQEL-NREIPAGLPPGTPVAHKTGQIS-GILHDAAIVYPPGQPAYVLVVLTRG -IP-DEAVARSLIVELSRQVYAH- ->[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=UPI000DD37AA0 ------------------------RDPHTNTRY-DFHAERLFHAASTMKVPVMIEVYRQAE -AGRFSLDDSLLVRNTSIVDGSAYRYRMLGRRMAIRDLVHRMITVSSNLATNLLIDLV-TA -DSVQATAERLGVRHMQVRRGVEDLLA-FRQGLNNTATAADLAVLLDALRRGAAVSPEADR -AMIDVLLDQQF-GDLIPAGLPPGVRVAHKTGAITR-IHHDAAIVYPERGPAYVLVVLTEG -IE-DQARSAELVAEVARGVH--- ->[subseq from] Serine hydrolase n=1 Tax=bacterium TaxID=1869227 RepID=A0A522YQY4_9BACT ---AMTAELQRTASSSRWRTALYVKDLQRGYEW-TYHAEDLFPAASLIKLPIMVGVFEKIQ -RGQLSLYSKLKLRRTTRMGGSGSLKWQRDGTYTVRYLLEKLIKESDNTAMLLLLDEV-GI -GFLQQYFPQMGLVYTEINSDGLRLDSG-GVRAENYTTAREMGAVLERIYRGELVNGFASE -LMLDILKRKRA-RSRLAKYLPPGWQIAHKTGLLRR-SCHDASIVFSPNGD-YVLVVLTGR -VD-SYPAAKDFIARLGKTTYRTy ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas TaxID=574697 RepID=UPI0007FB2B2B ----LTDTISKIVSGYPGEIGVAVI-INNMDTV-TVNNKSIYPMMSVFKLHQAIAVCNDFD -RKGLSLDSLMCIKRDELDPWSPMMKEHPEPVLTVKDLLRYTLIQSDNNASNIMFKELVSV -ARTDSFIATIPRTSFRIAYTEGEMSVDHDKAYSNYTSPLGAAMLMNRLFTDSLVSREKQC -FMMNTLEECITGKDRIVAPLKEGITIAHKTGSGYNGAHNDVAYIRLPNNVCYSLAVFVKD -FKGNEAQASKAVARVSAIVYA-- ->[subseq from] serine hydrolase n=1 Tax=Thermorudis peleae TaxID=1382356 RepID=UPI00068CFDCE -----PSQIAERIAHFPGQISLAASDLDRDWHL-AFRADNTVPSASVIKLLILAELYRQAS -RGALSLEAQVAIEQEHVVEGSGVLRWLSGLRFTVRDLATLMIIVSDNIASNRLIDIL-GF -AAINHLAAQLGLQQTSLRRPFWGRA-ARADEPENTMSARDAVALLRALECGMIVPEPLLD -EVRTILRAQQF-QECIPACLPPSVVVGNKTGSLP-GIAHDAAIIWAPQGR-LALAIFTTG -LT-DEHRGRCEISEIARACYNAw ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides caccae TaxID=47678 RepID=A0A174URT6_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGCNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TL46_9GAMM ---ELERRLEAVDAAYAGDIGVYVRHLGRDESF-SYRAEEPWYLASGVKVPIAIAVMRAIE -RGELALDTRVTLRESDFVDGAGGTNAYRAGTLRVSWLLEQMIVHSDNTASDVLIRTV-GI -EQVNRVAAELGRVDGMHITTLADVRRAYYATHANSASLVEFGRMLAALSEGRALGAEGTT -YLLDVMSRVQTGSRRIRAGLPAGTRFEHKTGTQHR-RTCDLGIATVPGRARVVIAACARG -T--ATAAGERALRDVGAAVT--- ->[subseq from] Serine hydrolase n=1 Tax=filamentous cyanobacterium CCT1 TaxID=2107702 RepID=A0A2P8VTW4_9CYAN ----LKGELENLATLTPGTPVAFAVDLDSGQYI-DLGGAEPVAAASTIKVPILIAFLQQVD -AGTVALNQSLMLQEEYMAGGSGTLREAVGTEYTALDVATRMIVASDNTATNMMIAALGGI -EALNQTFAGWGLEHTVLRNPLPDLDGT------NTTSAKDMALIMALVDQGGLLTPRSRD -RLFSIMQRTEN-VSLIPSGISDRSLTAHKTGDIG-GLLGDVALVDVPNGKRYTLALLVQR -PTND-GRASELIRRMTETVH--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium 35_41 TaxID=1897008 RepID=A0A1Q6U3F7_9BACT ------SSLRNLSAMYSIHPSIYVWDYETGNYA-DVNANEIFPTASIIKLPVLVQLFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFKSANSYTIDTLARMMITESDNSATNMIMARLGSM -TDINQGIREWGLKHTYVQTWLPDLGGT------NHSTARDMATILYNIDNPKFLSTSSRE -KIFDYMGHVHN-NRLIAAGLPAGAEFLHKTGDIGK-MLGDAGIVYAPNGKKYIVVIFANR -PHN-SPLGKEFIVKASEIIYN-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella intermedia TaxID=28131 RepID=Q8KT54_PREIN ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMVMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Archangium sp. Cb G35 TaxID=1920190 RepID=A0A1Q3HPX3_9DELT -----RASLQEIAQVKGATVAVAYQHLGNPKDSlFLEAERSFHAASTMKVPVMIEFFRQVD -AGKLSVGQELTLTNQSIVDGSPYAYERLGKPVPARELVERMITRSSNLATNTVIALV-DA -KRVTKTLRSLGARQMTVLRGVEDGK-AYQKGLNNTATARDLATLMAAIEQGRAASPASTQ -AMRTILLAQEL-NLEIPAGLPPGTPVAHKTGQIS-GILHDAAIVYPSGKSPYVLVVLTSG -IP-DEKVARSLIADLSRQVHA-- ->[subseq from] Class A beta-lactamase n=2 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3B8QUV8_9PORP ---ELESRIGRYIADKDARIGVAVI-IDGRDTA-EVNGSQFFPMLSVYKFPQALAVAEHCR -RHGVGLPDTVRVSADEMKSWSPMRDRFGAVNLPLLALLEYSLQQSDNNACDVLFRMIGGP -AVADSLMNKWGYGDIRIRSTEDEMHRDTDLCLVNCCTPLEMARLLDDFNTGIRLRSEENR -AIASLMESCVTGRDRLARPLTTPAILGHKTGTGDVDAVNDAGYVNLPDGHRYAVAVFMAS -SAYGLEDTSRMIADISEIVYS-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DBCD62 ---ALRQRIDRELNQQTGVFAVAFKDLTTGNEL-LIREREVFHAASTMKTPVMIEVYNQQA -QGKLALTDSILIKTESIVDGSPYTYKQVGSKRTLASLVYDMITVSSNLATNLVIERV-GA -PNVVQTMRDLGASDIQVRRGVEDTKA-FAKGLNNSTTAYDLMVIFDKIATGQAVNAEASK -AMIATLLDQKF-NDAIPAKLPKAVKVAHKTGSIN-GVRHDSGLVMLPDGRRYVLVLLSKD -IT-DDKAVINAYATVSAWIYQ-- ->[subseq from] Serine hydrolase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A3N2M6T1_9BACT --qELQQLVDSLVRDVPGTVGVAVI-TSEGDTV-AVNNDVRYPLMSVFKLHEALAVAHELD -SRNQSLDSIMTLQRSQLSEWSPMLKDYPKGDISVGELMRYILTVSDNNASNVLFDSIVSV -SHTDSFIRNLGIDSFRLQYTESQMQRDHAISYDNYSSPLSCAALVKRVFTDSIVSQEKQD -SIRQWMGKCVSATDRMMEGVADGARLYHRTGSGYTNAINDVGYIIMPDGRETALAILVKD -YPGEQSQADSLIASITTSIL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chthonomonas calidirosea (strain DSM 23976 / ICMP 18418 / T49) TaxID=1303518 RepID=S0EUC6_CHTCT ------ADVAAIEKASTGVLCFAAEDLQTRKVV-QHNAEHKCRTASVIKLPILVHVGLEVA -EGRRAWEEPLVLTDEEKVPGSGILSQLTAGLLTLRDVCVLMIVLSDNTATNMIIEHIGGV -NPINARMRALGLETTTCFRKVYARDALPNPYGLGVTTPREMLQLLEMIATGSLGSEALCE -EFLAILSKQHY-RDCIPRYLPEEWRYAGKTGSIDE-ARNDVGIVTDAVGNRFALALFCQE -LQ--------------------- ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=UPI000D0FDA46 -----------------GPAQVYFTDLATNQSL--YRGSSTLPSASMIKVFILARAYEDLR -NGSLSRKKTFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM -DRINSYLQSHGYSHSVLRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR -EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKGA-YVLVIFTRN -YTP-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7KVT4_9BACT ---SLRARIEARIAQAPARVGVYYRDLTSSDSL-TVGALTRFHAASTMKIPVMIQLFRDRD -AGLLSLDDSITITNTSIVDSSPYQYKRLGQRAPIRELIELMETVSSNLATNLLITKV-DA -KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIATGKAAAPASCR -EMLETLGRQHF-NEGIPAGLPAGTTVYHKTGWVGQVVYHDAALVEAPHGGKYVLVVTTGG -IQKD-DDAHALVRDISKLIFD-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8U8C6_9BACT ---RLEANVIRITKSVNARWGIYMKCLETGEEI-AINADDQMDTMSVIKIPLMVEAFRQIE -AGKFALSDRVTITDSAKRPGTGVIRSMDAGALTIKDLLTLMIIVSDNTATDLMYEKVGGV -EPVNRLMESYGLKSIRAMGTAEMWFSQQGRTPFGLSSPRDMGRLLENIEKGEAVSKSASD -QMLQIMRGQVY-GSRLPKYVT-GYRVPHKTGDFLPYIGNDVGILESPHT-NIVLSVFTAH -HFGIGANLEDAIGRIAELVANYy ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Sphingobacterium daejeonense TaxID=371142 RepID=A0A4U9JPN8_9SPHI ---------------------------------------------------LHWQFLDLVD -KGKLSLDQTVKVGKKDLMPWSPLRDENPNGGFTIEKLIQYAVSHSDNTACDVLIKLVGSP -KDVEKYFKKNNIQDIQITYNERDMQAKWENMFQNWTTPKAASKTMMLFYEKEPISKNSYF -VFWRTNFETTTGEKRIKGKLPVGTHVAHKTGWSGTAAVNDIGIVVLPNDQHFYISVFITE -SKENFDSNEELIADIAKAAYDYf ->[subseq from] serine hydrolase n=1 Tax=Negadavirga sp. SW125 TaxID=2164132 RepID=UPI00130078C0 ---------------------------------yAQNENKQIPSASIIKVPILIFLFMEVD -KGSLDLDEKVVLEEKDKVGGAGMLRENPDGSFTWRYLATEMIRISDNTATNMLINRL-GR -TRIQTWLEEEGFKHTILDRLMMDFE-AIAEGRQNFTSPNDTNRLFMGLYNGQWLTENSKV -EALFMLKNCAD-NTCIPGQLPPGVEIAHKTGTLDY-VRGDAGIVFG--TSPIFLSVFVEG -FK-ELTEAESIIAEISRIVFEE- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=Acidaminococcus fermentans TaxID=905 RepID=D2RJL4_ACIFV -----------------GPAQVYFTDLGTNQSL--YRGSSTLPSASMIKVFILARAYEDLR -NGSLSRKETFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM -DRINSYLQSHGYSHSVLRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR -EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKG-SYVLVIFTRN -YTP-------------------- ->[subseq from] Beta-lactamase TEM n=1 Tax=Clostridium neonatale TaxID=137838 RepID=A0A650M7L0_9CLOT ----LTNRINYIIKNSSADIAVLVKDLKEDKVIfKYNEDKKYVSASIIKVPIMIEALSRVD -LGEINFDDKFNIGDDNKVDFSVITEQDLK-ECTFEELIEWMIISSDNTATNVLIDIL-GL -ENINDRIKKLNMKNTLLERKMMDFK-AIEYGRNNYTSLNDMLIAMEGLYRGVLISSEMSL -KAIDILKNQRD-NFMLKRYIRDNVTLANKTGELDK-LNNDVGIFYTKNHN-YFIGIFVHD -VKKN-KDAYEIIGKISKEVYDYy ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6DSG3_9BACT -------------------MGLAIVDLIDGRTI-LRNADREFPTASSIKIAILLELYHQDQ -QAKAKLDDVYDFDPKELVEFSQIMSGLTPGVVTNRDLAQFMVAVSDNTAANILIDRV-GK -DNVNAMLRGLGLTKTMLRRKMMDFAAA-RRGEENVSTPQEMTRLLEAIYKSKLLNKELNQ -QLIKQLSTLKE--SYIPHDLPAGVQVANKPGNLQN-VRTDSGIVFVKDH-PFAMSVMTSN -AR-DERAAERAISEIALEAYRYf ->[subseq from] Beta-lactamase n=1 Tax=Prevotella denticola TaxID=28129 RepID=Q8KT55_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNGFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Leptolyngbya sp. PCC 7376 TaxID=111781 RepID=UPI0013580CAD ---------------PELDATMLFVDLDTGEYL-DVASSRSISAASTIKIPVLVAFLEAVD -QGTVQLQDSLIITDNVKGGGSGNFQYKDNGTLSALFVASEMSINSDNTATNMIIEQLGGF -EVLNQKFQSWGLQQTQLNAPLPDLEGT------NLTTARDLAFLLAKISRGDILSNRSRD -RLIRIMSSTRN-DNLLPQTLGQGAAIAHKTGDIGY-IIGDAGIIDLPNGKRYIASIFVER -PY-DAPKGKELLHKIGKLFYQH- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium oryzae TaxID=1450648 RepID=A0A1V4IA85_9CLOT -----EKAIIDYMKNKDIQYSLVIKDLHNDECIiDVNGNTKIQSASIIKLFIMARAFEMTE -NGELSLEERIAITKKERIPYSIVYLLDENTTYTIRDLITLMIIQSDNTATNVLIERL-KM -SNINDFNARYGFTKTSVKRKMLDFETR-EAGIDNETSAADAARFLQLAYKGKLVSEKASE -QMLEIMKNQLD-YSMMKLDLPDDVIIAHKTGDLTN-IKNDVGIVYSNKGD-YIFSMFTWN -AK-SDNYARNVLGRVSSMFYSYf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6IGM4_9BACT -------------------MGLAIVDLIDGRTI-LRNADREFPTASSIKIAILLELYHQDQ -QAKAKLDDVYDFDPKELVEFSQIMSGLTPGVVTNRDLAQFMVAVSDNTAANILIDRV-GK -DNVNAMLRGLGLTKTMLRRKMMDFAAA-RRGEENVSTPQEMTRLLEAIYKGKLLNEELNQ -QLIKQLSTLKE--SYIPHDLPAGVQVANKPGNLQN-VRTDSGIVFVKDH-PFAMSVMTSN -AR-DERAAECAISEIALEAYRYf ->[subseq from] Beta-lactamase enzyme family n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KNZ6_9BACT -----------------------------------------------------LAVLDKMD -KGHIALDSLIEVKSSQLKSYSPLRDKFPDQDISLGELLKYSISQSDNNACDILIEYAGGI -DQVNEYVKSLGIKDCNLAATEDLMHTS-GDAYLNWSTPEEVVRLLNIADKHPLFGTQYKD -FLQAIMQETSTGKDKLKGQLPADVIVGHKTGSSDRTADNDAGFVILPNGQKYYIAVFVME -SQENDADNAAIIASISKIVYDT- ->[subseq from] serine hydrolase n=1 Tax=Nocardia otitidiscaviarum TaxID=1823 RepID=UPI0011DE2CCF -----ETRIRAVFADAGCTGWLHARRCDSGTEI-SLGGDERVVVASVYKLPLFVAFCRHID -AGRIDPTARITVTPSDCTPPTGIAALRDPVTMSLRDLAASMMTVSDNAAADVLLGEI-GL -AAVEELLDDLGLIRTRIIGGTADLHRAYDPSYTSATTPEEMTRFLHALWRGDILSPERTD -YARAVMRAQVW-QHRIAAGFPRSVTVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPAVDAAIAEVARIAVT-- ->[subseq from] Class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y8E2E6_ECOLX ------------------------------------------------------------- ---------------------------------------------------------MGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase, putative n=1 Tax=Leptolyngbya sp. PCC 7376 TaxID=111781 RepID=K9Q5U0_9CYAN ---------------PELDATMLFVDLDTGEYL-DVASSRSISAASTIKIPVLVAFLEAVD -QGTVQLQDSLIITDNVKGGGSGNFQYKDNGTLSALFVASEMSINSDNTATNMIIEQLGGF -EVLNQKFQSWGLQQTQLNAPLPDLEGT------NLTTARDLAFLLAKISRGDILSNRSRD -RLIRIMSSTRN-DNLLPQTLGQGAAIAHKTGDIGY-IIGDAGIIDLPNGKRYIASIFVER -PY-DAPKGKELLHKIGKLFYQH- ->[subseq from] serine hydrolase n=1 Tax=Olsenella sp. oral taxon 807 TaxID=712411 RepID=UPI00067D6659 ---AVRAAVEPLVSPYGDEVAVVYTPVDAPDGGfAINGDERMRSASMIKTLIMATLLQHEA -DGSISLGDSYTIRESDIVGGTGSVQSMGAGTLSLSRLAELMISQSDNVATNVLIDRL-GM -GTVNDEGARLGLGQTVLARKMMDTAAA-AAGRENYTSASDQARILRLVASGDLASPEASQ -AALAWLKEQED-SEGIAQGVPSGTVVAHKTGTLDS-VRHDGAIVYG--KRPYVLVIMTHG -MS--DGAANSLMARVSRTVWD-- ->[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A355BVB8_9BACT ----LIADIRGYLPKDNGIYAVAYLDISSGEKI-LIHEHETFHAASTMKTPVMIEVYKQAA -EGKFSLNDSIEIKNESIVDGSPFSYKMIGRKKTIYDVLYGMIIASSNLATNILIEKV-DA -QNVMETMRSYGAHDIKVLRGVEDTKA-FRQGLNNQVTANDLMLVFEKIARGEAVSPEASE -AMVKILLDQKF-NDIIPAQLPKDVKVAHKTGWIT-GLHHDSGIVMLPNGKKYVLVLLSKE -LK-DEKAGVEALATVSKMIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6C1P5L2_9BACT ------------INTVDGDMAVVMLGMDDAAGHvLINENERFHAASTMKTPVMIEAFKQAE -EGKFSLEDSILVKNESIVDGSPFSYDKLGTRVPMRDVIYDMITRSGNLATNLMIDLV-GA -ENANRTMHDLGAVNIQVLRGVEDMKA-FDQGLNNETTAMDLAIIYREIAGRSVVSEQACD -EMIAILKDQHF-RDMIPAGLPDDVQVAHKTGSIT-GVKHDSGIVYLPDGRSYVLVILSKN -LSNN-DDGRDAGAEISRLIYEHy ->[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. R14 TaxID=2705549 RepID=A0A6B3PR01_9BACT ----IKEKISREFLSVQGTFALALKDLQTGEEI-LINERETFHAASTMKTPVMIEVYKQAA -AGKFNLSDSVTIHQNSIADGSEYIYKLKGSKMDIYGLLYRMIIRSSNLATNMIIELA-GA -KNITRTMRDIGANDIQVLRGVEDIK-AYEKGMNNTTNAYDQMLIYSALANGKIAGIESTK -PMIDILLKQEF-NEMIPARLPKDVKVAHKTGSIT-GIQHDAGIVYMPDGRKYVLVLLSKD -LK-DEKEGIAVMSRVSELVYN-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Siphonobacter TaxID=2635712 RepID=A0A2N7B4W1_9BACT ---SLKEQIQHYLSGRKGTYAVAYKNLATGEHV-YINENDSFHAASTMKTPVMLEVYRQAY -KGKFSVLDSIVVKNESIVDGSPYSYEKVGQKRTIYDLMYEMIIYSSNLATNIIIDLV-DA -RNVTKTLCKMGAKHTQVLRGVEDKK-AFAQGLNNKVSAYDLALLFEKIAKGKAVSPEASQ -AMISILLDQKF-NSVIPAKLPKSVKVAHKTGSIVS-IMHDSGIVYLPDGRKYVLVLLSKN -WQPDREAAVETMATVSEMIYQ-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SBF9_9BACT --dSLKSSIEKYLKDKKAKVGVAILGIEDNFKL-NVNEKHHYPMQSTYKFHLALAVLDKLD -KENISVDKKLFVKKSDLLPWSPLRDKYPNGNLSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTNWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLK-GLFAGW------------------------------------ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Lunatimonas lonarensis TaxID=1232681 RepID=R7ZPQ9_9BACT ---KLNQEIKALFEETAGDFAMAFRLLNTTQTL-LINERESFHAASTMKTPVMIEVFKQAE -EGRFSLSDSIPVINESIVDGSTFSYSRIGLQASIYDLTYQMIIKSSNLATNLLIKLV-NA -KAVTQTLRELGAADIQVLRGVEDQK-AFDAGLSNTTTALDLMLILEAIATGNAVNREAST -EMMKILGDQYF-KDLIPKYLPETVRVAHKTGSIT-GVQHDSAILELPDGKRYVLVLLSKN -LT-DAAAGKETIAQVSKLVYEY- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI0013307591 ------------------------------------------------------------- ------------------------------------------------------------- -----AFARAIGEETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNTTGAASIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQ -PQQNAERRRDVLASAARIIAE-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. B2A1 TaxID=2081964 RepID=A0A2S0JQ72_9BACI -----ERAIQRVLDEAPYNVHVFVKDANTNHYFiQEKFQAVFSSASLIKVPILLGVLHYLE -GNNQDIHQEIEVAPKEWVDYSVISEQRIEQ-STIYELLVWMIITSDNTATNVLIDFI-GI -DVFNHYFSQIGLHQTKLQRKMMDFEK-LERGIDNLTSANDMAHLFSRIYQQDLLSTKFSK -LTIDILSRQRV-HESLKRYLIDDVKMAHKTGGLET-VDHDVGIVYNGSN-DYLIGVFITD -VI-NNEYAKQLIGRISKIVYEHf ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7IRU6_9BACT -----REQLAARVARAPATVGVYYKSLSRPDSL-LLGANLRFHAASTMKVPVMVQIFRDAD -EGLLRLDDSLAVHAASLVDGSPFEYRRVGGKASIRELLELMITRSSNLATNLLIERV-GA -ARAQASARGLGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGALLAAIAQHRAASPSSCE -EMLRILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAALVYPPSG-SYVLVVLTGG -IKED-SVAHNLVADVSRMVWE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lihuaxuella thermophila TaxID=1173111 RepID=A0A1H8FFP9_9BACL --qKLREQLEEWKLKLPGRWGVWIEDLTTRDSW-EWNGDHSFYAASVIKVPIMVAVFREAW -KGRFALSDEMTLTPEAQVGGAGVLQHLTPGLVSIRDLTTLMIIQSDNTATNLLIELV-GK -DAIHEAMTELNMNGSRFYNPLMILPADR--EGVNTITPRDLASCYRKIAKGEAVSYHASL -QMINILKKQQI-RDCFPSLLPQTWELAHKTGTVTR-VLHDTGILYTGSHA-VIMVALSED -CS--YREAKEQLAQLAFRVYQAy ->[subseq from] serine hydrolase n=1 Tax=Muricauda sp. 40DY170 TaxID=2499163 RepID=UPI000F8CE039 --eALETKVQTQIDSIEGDVAVAFLNLSDPTDTlFINQNEEFHAASTMKVPVMIELFKQQA -SGKINLNDSILLVNESIVDGSPYRYDKIDTKVAINDLMYSMITVSSNLATNVLIELV-DA -KKVTATMRDLGADKIEVLRGVEDIK-AYELGLSNSTTAKDLLVIMESIATNKAGTETDCK -AMVDILKDQQF-NDMIPAKLPKAVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVVVLLSKN -LK-DFDKGTEQLADISKTIYDY- ->[subseq from] Beta-lactamase n=2 Tax=Luteimonas sp. FCS-9 TaxID=1547516 RepID=A0A0H1AUH6_9GAMM ---ALDRRLRAVDARLSGEIGVYVQRLDDDATW-GLRADESWYLASGVKVPIAIAVLREIE -QGWLTLDTQVALRDDDFVDGAGGTNAHRAGALPIAYLLEEMIVHSDNTASDVLIRTV-GL -GQVNAVAAELIAAQGVRITTLSDVRRSYYATHVNSATLRDYGRMLAALQRGQALDPAGTR -QLLGLMARVQTGTRRIRAGLPPGTRFAHKTGTQYR-RLCDSGIATLPGAHPAIVVIVACV -RGADTQAGERALREIGAAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537HUS7_9BACT ----------------SAQFGVAFKNVQTGETL-LMNEKESFHAASTMKTPVLIELFKQAS -TGKFSMSDSIEIKNNSIVDGSEYSYKVIGQKRTIADLAYNMIILSSNMATNMLIELV-TA -DSVMKTMKSLGAKDIQVLRGVEDSK-AFEKGLNNTTTAYDQMLLYNLLAKEKLVNKEASN -EMTRILLDQKF-NTVIPAKLPPEVKVAHKTGSIT-GVQHDAGVVILPDGRKYVLVLLSRF -KKEDEKKVIEAMAAVSKLVYDY- ->[subseq from] Beta-lactamase class A n=2 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=A0A1N7D2A4_9BURK ------TAVQQLDSHPQTGLGVYVLDLATGQSF-GHRAEERWYLASMVKVPVAIAVLQAVE -RGDITLDTTVTLRAGDRVDGAGATLRQPGASLSVRWLMGQMIIYSDNTATDMLIDLV-GL -QAVNGVVQALAPRGIARITPLAEVRRAYYAEGLNSGRLDAYAQILVALAEGRALGAEATQ -TLLKLMEDVATGPQRLRAGLPPQARLAHKTGTQRR-RICDAGLVRMPARHPVALVACVRD -AP-SLTRAEHLLAQTAAALC--- ->[subseq from] Beta-lactamase n=1 Tax=Clavibacter michiganensis TaxID=28447 RepID=A0A251XXF7_9MICO ---AADAAFTALEERFDARLGVHLVDTATGAEV-SWRADERFAYASTIKAPLAAALLDRVG ---IAGMDRAVPIEAADVLSYAPVTETRVGGTMTLRELAEAAMTRSDNTAANLLLEALGGP -AELDAALTALGDETTVVSRREPDLNEATPGDDRDTTT----------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:768 TaxID=1262838 RepID=R7HYF1_9CLOT ----LESQLNNLASMYSIHPSIYVWDYETGNYV-DINANEIFPTASIIKLPVLVQLFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYSIDTLARMMITESDNSATNMIMARLGSM -TDINSGIRQWGLKHTYVQTWLPDLGGT------NHSTARDMAEILYNIDNPQFLSTSSRE -KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVFAPNGKKYIVVIFAHR -PHN-SPLGKEFIVKASEVIYN-- ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI00037AEF7E -------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE -EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV -DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLARGTAISLAVSE -QMVNLLTRCQG-PVSIAKNPTKEVIVAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. HV4-5-A1G TaxID=2004595 RepID=A0A5M9NXU7_9CLOT ----------------KLNCAFMVENLKTGEKA-AYNEKVVVPSASLIKIPIMMEVFKQVK -EGKLSLKQRITVENDVKVPFSILNLLESGSSYTLKDIITLMIIQSDNTAANILIDLA-GM -DNVNDYIKSLKIKDTTLQRKMMDSLAR-KEGRENKTTASDMVKFFEIIYRGEKSGEPYSI -MMKDILINQLD-NSVMRLDVPDETTIAHKTGDLD-GISYDVGIVYLPNVD-YIFCGLTWN -AV-TNNFARKTIGRISRIAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. 21C1 TaxID=1843690 RepID=A0A1E4V4X2_9PSED --aELQERLERLDAESPGKLGVYVEHLSEGH-L-DYQAEGPWYLASTVKLPVAIAVLQGVD -KGRLSLDQAVELTAEDKVDGSGGTWSDVGTTFSIRTLLEEMLRESDNTAADMLIRLV-GV -DTLNASLERYGFSQTSLLQVRQDLYAELHPDARNLS------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. 21C1 TaxID=1843690 RepID=A0A1E4V4X2_9PSED ------------------------------------------------------------- ---------------------------------------------------------I-GP -ERVQALANALGLTPGQLEQDLDEAYRRYYAQGRNSSSLTGYGALLRDLVRGELLSDASQQ -LLYQLTGLNQYEAYRLEAGLAEDLPFIQKTGTQQ-GRACHVGVARPETPEQALIIIACAA -DLDENREAGALFERIGEAIQ--- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=A0A1I5GMB2_ACIFE -----------------GPAQVYFTDLATNQSL--YRGSSTLPSASMIKVFILARAYEDLR -NGSLSRKETFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM -DRINSYLQSHGYSHSILRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR -EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKGA-YVLVIFTRN -YTP-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus chordae TaxID=237019 RepID=A0A2W7RTF4_9BACT -----LSTIDAQLDSIQGDVAIAFYNLSSTDRL-MINAEEEFHAASTMKVPVMIELFKQQR -AGKLNLNDTILLKNESIVDSSRYSYGKIGTKVSLNDLLYPMITVSSNLATNVLIELV-GA -KNVTATMRNLGADKIEVLRGVEDQK-AYDLGLSNSTTAKDLMIIMKAIATNQAGTPDDCE -KMISILKDQQF-NEIIPAYLPKDVSVAHKTGSIT-GVHQDAGIVYLPDGRSYVLVLLSKN -LE-DFDQGTDQLARISKTVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A419EFS8_9CHLR -------RLENFISQFGKTVSTAVYDLQTGDEI-LIGADVTMHPASTMKVPVMMEMFRQAE -AGLLSLDERLTIFNSSIVDGSEFSYARIGESETIRKLNRLMIIRSSNLAANLLMERV-GT -SRVDAFIKELGIADMTVIRGLEDKK-AYRLNMNNSASARSSTHMLRLIVEGKVVSKEACD -EMIRVMLGQEF-NESIPALLPADVKVAHKTGWSSD-FFHDIGIVFPPRRKPYVISLFTQG -FPNDESQAHDCMAQISKMIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus shackletonii TaxID=157838 RepID=A0A0Q3X0I1_9BACI --------------TTGGTWGIYLEDLDKNETW-SWNENEVFYAASIIKVPIMAAVFSAFD -EGLFKLSDTIVLKREELVEGGVLQHLTPGIRLTIYDYLTLMIIQSDNTATNVLIDLV-GV -EKIQEMMAEIGMRNSCFYNKLNTVPVK--TNGRNMITARDMAVLLKKLTSGMIISQYACE -QMIDIMKKQQF-RDCLPYKFPQEWEFANKTGWVT-GIRHDIGVLYVGRR-TMNIVVLSKD -VE--DKLAKQTMAQIGECIFNY- ->[subseq from] serine hydrolase n=1 Tax=Acidaminococcus fermentans TaxID=905 RepID=UPI0008952775 -----------------GPAQVYFTDLATNQSL--YRGSSTLPSASMIKVFILARAYEDLR -NGSLSRKETFTLTPENVVGGAGVLQGRPYGTVPLQEALDLMITESDNTAANLLIDRL-GM -DRINSYLQSHGYSHSILRRKMMDTKA-MEEGRENMTSTRDVALLFKRLYRGNCVGPAQDR -EMLEIYKRQTD-NDSIPGDLPQGTVVAHKTGEVSD-VRHDGGIVYTPKGA-YVLVIFTRN -YTP-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A0Q2LV61_MYCGO ----------------HADVAVFFRPLGGGSEW-SYKPDDTFHAASTMKVPVMIELFHQAR -QGKLALDDPLLIHNESLVDGSAFYYRSEGQTRTLRELCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARGLAILLTAIAQGKVVDPDSSR -QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-GIHHDAAIVY--GRQPFVLVILVRG -MTNS-EDSSALMADITRVFYR-- ->[subseq from] class A beta-lactamase n=1 Tax=Caulobacter sp. Root487D2Y TaxID=1736547 RepID=UPI0006FD5C92 --qKMTADFQPIADRVPGHLGVAVEDLGTGQII-SFNGERRFPLQAVFTAPLGAAVMAEVE -AKRLRLDDILLIEDVDLSPPSGVADLWAGPMYSVQDLLERAIRDGDNTAADILMKRIGGP -GAVTAWLQGRKVNALDIDRYQRQLQPAYLADPRDTATPLGALRFLEAVNQAELLGPDSRR -LLGRIISQTRGGAGRLRAAVPEGGRLNHIPATARTDVVNDIGVYTLKDGRKFAVVAFISG -SPLPVAEQEKAIADVGRVVIK-- ->[subseq from] Beta-lactamase n=1 Tax=Fusobacterium sp. CAG:439 TaxID=1262899 RepID=R7J4T0_9FUSO ----LENQLNNLSAMYSIHPSIYVWDYETGDYA-DINADEIFPTASIIKLPVLVQLFRSIE -KNQLTIYDEMPLTEYYRTEGSGSLQFKAANSYSIDTLARMMITESDNSATNMIMARLGSM -TDINSGIREWGLKHTYVQTWLPDLGGT------NHSTARDMAQILYNIDNPQFLSTSSRE -KIFDYMGHVHN-NRLIAAGLPAGATFLHKTGDIGK-MLGDAGIVFAPNGKKYIVVIFAHR -PHN-SPLGKEFIVKASEVIYN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lutispora thermophila DSM 19022 TaxID=1122184 RepID=A0A1M6FJQ9_9CLOT -----DQDIMKSFQNDVGNVSIVLKDLKNDALMfQLDPHRVVASASTIKILIMIEALRQIM -EQRLSFDELVEVKDEDKVDFSIITELNVK-HYSIKDLITLMIITSDNTATNILIDIL-GY -GNINKMAEDLKLEGTVLRRKMMDFEAA-KQGKQNVTTAWDMAVMMEALYKGTILDESMCQ -VALDILKRQQH-KDLLTRYIADDIVVANKTGDLQN-LNHDIGIFYHPYTD-YLLGVFVTD -AE-SNIGAKHIIGKVSKTVYDYf ->[subseq from] serine hydrolase n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001413460D ----LKKAIQAKLAGVEGNFGVAFKDLQSNQTL-FINEKENFHAASTMKTPVMIEVFKQAK -GGKFKLTDSILVKNESIVDGSAFSYKMIGKKMTIYDLTYQMIIVSSNLATNILIELV-DA -KKANATMRDFGANDIQVLRGVEDSK-AFQLGMNNSVTAYDLMVIFEKIARKKAIDPTASE -GMTRILFDQKF-NEIIPAKLPKEVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKN -LK-DPKAGVRILADVSEMIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=A0A327JBR1_9BACT ----LKKNLTNLSLAYTIEPSIFVWEYDSGKYV-DIKADKEFSAASIIKIPVLLETFKAIE -TGKLSIDDKMSLTEYYRSDGSGKLKYHQSGSYTIDELARIMIEQSDNSATNMLIAAVGGM -PEINSALKNWGIKNTHLQNWLPDMAGT------NVTTTKDLAVMLYNIENSQFISSKSKS -YIVDYMSNVEN-NRLIQAGLPQNASFIHKTGDIGK-TLGDAGIVTTASGKKYIVAIIANR -PYN-SPLGKDFIQKASSMIYN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas cuatrocienegasensis TaxID=543360 RepID=A0A1H9CU39_9PSED --aELQERLERLDAESPGKLGVYVEHLSEGH-L-DYQAEGPWYLASTVKLPVAIAVLQGVD -KGRLSLDQAVELTAEDKVDGSGGTWSDVGTTFSIRTLLEEMLRESDNTAADMLIRLV-GV -DTLNASLERYGFSQTSLLQVRQDLYAELHPDARNLS------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas cuatrocienegasensis TaxID=543360 RepID=A0A1H9CU39_9PSED ------------------------------------------------------------- ---------------------------------------------------------I-GP -ERVQALANALGLTPGQLEQDLDEAYRRYYAQGRNSSSLTGYGALLRDLVRGELLSDASQQ -LLYQLTGLNQYEAYRLEAGLAEDLPFIQKTGTQQ-GRACHVGVARPETPEQALIIIACAA -DLDENREAGALFERIGEAIQ--- ->[subseq from] serine hydrolase n=1 Tax=Chthonomonas calidirosea TaxID=454171 RepID=UPI0006DD4A43 ------ADVAAIEKASTGVLCFAAEDLQTRKVV-QHNAEHKCRTASVIKLPILVHVGLEVT -EGRRAWEEPLVLTDKEKVPGSGILSQLTAGLLTLRDVCVLMIVLSDNTATNMIIEHIGGV -NPINARMRALGLETTTCFRKVYARDALPNPYGLGVTTPREMLQLLEMIATGSLGSEALCE -EFLAILSKQHY-RDCIPRYLPEEWRYAGKTGSIDE-ARNDVGIVTDAVGNRFALALFCQE -LQ--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. Root1455 TaxID=1736465 RepID=A0A0Q7SXT2_9CAUL --qKMTADFQPIADRVPGQLGVAVEDLGTGQII-SFNGERRFPLQAVFTAPLGAAVMAEVE -AKRLRLDDILLIEDVDLSPPSGVADLWAGPMYSVQDLLERAIRDGDNTAADVLMKRIGGP -GAVTAWLQGRKVNALDIDRYQRQLQPAYLADPRDTATPLGALRFLEAVNQAELLGPDSRR -LLGRIISQTRGGAGRLRAAVPEGGRLNHIPATARTDVVNDIGVYTLKDGRKFAVVAFISG -SPLPVAEQEKAIADVGRVVIK-- ->[subseq from] serine hydrolase n=1 Tax=Aquisphaera sp. JC669 TaxID=2712864 RepID=UPI0013EAFDE8 ---TLAGRLDPLIRAYKGKVAIAVKNLKTGEEF-HHRGGEVMPTASLIKFPVMVEAYRQAS -QGKIDLDARVALRVEDKVPGSGVLTDHFSAGIALKDAVRLMIMFSDNTATNLVLDAI-GI -GATAATMESLGYPNTKIHSKVFRRDTRSKKYGLGSTTADEMVRLCQALHEHRLVSPAASD -RMLEHLRTCDD-RDKFPRGLPYGTKLAFKTGSVDD-ARTCAGLIECPGGT-VAVCVLTCE -NEVPDNAGNLLCAEVARAVFDHf ->[subseq from] serine hydrolase n=1 Tax=Desulfosporosinus sp. FKA TaxID=1969834 RepID=UPI001124DE33 --dKLARDIKKIIQNERGSYSISYQDTISNNNL-VINP-QKMTAASMIKLFVMIESYNQIK -EGVINENEKITLTSSMKVGGTGSLSSRKDGTLTIDQLIYLMITQSDNTATNILIDRI-TM -DKINTTVQKLGCLDTVLQRKMMDFKAQ-GEGKENYTSAADLCNILTKLYKNECLGEKYDP -KMIEILKRQEN-NTKLPLLLPAGTVVAHKTGELDQ-VENDAGIIFTPKGA-YVLCVLSSG -IVA--GDARTIIAKVSKVVYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=A0A2T2WJP0_SULTH -------ELQNLIQTLPGRYAVFAKNLETQKTF-AYHEHDIFPSASVIKVPILIELYRRVE -EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV -DWVNSTIRRLGTQNTELIRKLQRVPAE--YDQINHTCAYDMALLMEKLATGTAISLAVSE -QMVNLLTRCQG-PVSIAKISAKEVIIAHKTGSLSE-ASHDVGIVYSPHMN-YVAAILSEG ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium jeungdonense TaxID=708087 RepID=UPI0013D21E15 --eTLEKDILSLMQATEGDFGIAFRMLDSGSQL-LINEKEVFHAASTMKTPVMIELFKQAE -EGKFDLQDSILIVNESIVDGSTFSYEMIGEKTTIYELMYQMIIKSSNLATNILIDLV-GA -DNVTQTMRDLGAEDIEVLRGVEDLKA-FDAGLSNTTTALDMMLIMEAIALGKV---EGSE -EMVTILSDQYF-KDLIPKLLPEDVKIAHKTGSIT-GVQHDAAILELPEGKRYVLVILSKN -LV-DVAAGKETIARISRLVFEY- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. BL4 TaxID=2478710 RepID=A0A3L7B7Y8_9ACTN -------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDRVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---ETGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IGL9_9BACT ---SLKEQIQHYLSGRKGTYAVAYKNLATGDHV-YINENDSFHAASTMKTPVMLEVYRQAY -KGKFSVLDSIVVKNESIVDGSPYSYEKVGQKRTIYDLMYEMIIYSSNLATNIIIDLV-DA -RNVTKTLCKMGAKHTQVLRGVEDKK-AFAQGLNNKVSAYDLALLFEKIAKGKAVSPEASQ -AMISILLDQKF-NSVIPAKLPKSVKVAHKTGSIVS-IMHDSGIVYLPDGRKYVLVLLSKN -WQPDREAAVETMATVSEMIYQ-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Pla108 TaxID=2528001 RepID=A0A5C6A2J8_9BACT --eALDKALGPMLKGHQGVVTVAIKHLETGDSF-AYDAERPMPSASMIKLPIMLTAYHAAL -EGKLSLDDQVVLKEEDKVPGSGLLTENFTAGLTLRDAIRLMIGWSDNTATNLVIEAIGGI -HAVNKLMKALDYENTRLNSLVFRGDTTIDPERSGVMNAADTIDLLEKILTDKEKVESMRK -EMMGHLRACQA-KNTLPRMLPAGTVVAHKGGSVT-ASRCDGGVIESPTG-PIIVCVMTTD -NEDADAEPMTLIAEVGKAAYDYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Pla108 TaxID=2528001 RepID=A0A5C6A2J8_9BACT ----------------------AIADGETGEVLwGFNEDGTRDPASTTKMMTAYVVVKLAE -KDPSVLDEVITFSERADKTSGSTSDVNAGEQVSVRELLYGLMLPSGNDASVAFAEHFGGE -SPYDRFIAEMNATAKDLGMDETGYRNHGLTAEGHVTSARDLVKLAHAAMQNELF------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Rhodocytophaga sp. 172606-1 TaxID=2704465 RepID=A0A6C0GIK0_9BACT ---AIQQQIQHELNSIPGTFALAFINPDNPKQQlLINAKEVFHAASTMKTPVMIEVYRQSS -QGKFSLQDSILVKNESIVDGSLYSYKMIGKTMTIEALVYDMITYSSNLATNILIDKV-GA -KNVMITMKALGANDIQVLRGVEDSK-AYQQGLNNTTTAYDLMLIFQKMALHQLVNAEVDQ -AMINVLLEQKF-NEIIPAALPKSVKVAHKTGSIT-GVQHDTGIVYLPDGRKYVLVLLSKN -LQ-DSKQGIAILSKVSGIIYRY- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus halophilus TaxID=226505 RepID=A0A1N6G5X6_9BACT ----LRENVLAQLDSIQGDVAVAYINLADPSDTlMIRASEEFHAASTMKVPVMIELYKQQE -EGKLDLSDSIVLVNESIVDGSPYSYSKIGTTVSINDLTYSMITVSSNLATNVLIELV-DA -KNVTATMRTLGADKIEVLRGVEDQK-AYDLGLSNSTTANDLMMIMKAIAEDQAGTPADCE -EMISILKDQQF-NEIIPFYLPKDVTVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LE-DFDKGTNQLAKVSKLIYDHf ->[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A6A0I1D1_9BACT -heKTEAKLWEIAGNVSGVMGIAALDLTSGERF-GVNENMIFPQGSAIKIPVLMEVYKQAT -EGKFRLMDLRWIDKEHKVGGSGILQQLGDHTLSIRDLAILMIVLSDNTATNMLIDLV-GM -ENVNRTMSSLGLTQTRLQRRMINAAAS-GKGEENLSTPFEAVRIMEILHRGEFLNRQVCD -EILEILKKPKSG--GLNAGLPANLPAAFKPGGIP-GVSTEWAIVYLKER-PYAVAVMEKY -EM--NGEAKSAMKEISRILYDYf ->[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A3A0C506_9BACT -------------------MGVAFRDLETGQEY-FFNEKSMMHAASTMKVPVMIEVFRQVE -AGKFRLEDSVFVRNQSIVDGSPYSYKVIGQKMSVHDLVYQMITVSSNLATNLLIELV-DA -KKVMATLQQLGIHDMQVLRGVEDGK-AYQLGRNNRTNALDLMLCLQAIAEQRAAGPASCQ -TMIAILKDQKF-RDSIPAGLPEGFIAANKTGSIT-AINHDAAIILHPNRKPIVLAILTRK -IT-NHEQARATIAGLTRHLF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Niastella sp. CF465 TaxID=2135684 RepID=A0A4R2W0F0_9BACT --nKLKDQIGSKLAEQPGDFAVAFKDLTTGESI-LINELTFFHAASTMKTPVMIEVYKQAA -AGTFSLNDSFTLKNESIVDSSSFSYKHLGEKRTLYSLVYDMIISSSNLATNMVIELV-NA -RNVTQTMRQLGAGKIQVLRGVEDSK-AFAKGLNNVTTANDLLVIFEKMAKGEIVDSASSQ -AMIKILLNQQF-NEIIPARLPKDVSVAHKTGNITN-VLHDSGIVLLPNGKKYVLVLLSKN -LQK-EEQAKNAMAEVSEMIYKY- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacteroides thetaiotaomicron TaxID=818 RepID=B5WXV7_BACT4 ----LTDSISQIVSACPCEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=R7LYN1_9FUSO ----LQSELQNLAKLYTVEPSVYVWDYETQNYV-DINASKIYSTASIIKIPVLIDVFKSIE -AGQISLEDKIPLTEYYRTEGSGSLQFKARNSYTIDELARRMITESDNSATNMLMAKVGSM -TDVNQSIRDWGLKNTEVQTWLPDYAGT------NHTTAREMADMLYNIDEDKFLTEASRT -KMLDYMGHVHN-NRLIQAGISPDAVFLHKTGDIGS-MLGDAGIVIAPNGKKYIVVILANR -PH-NAIAGKDYIVHASEIIYNY- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. JC631 TaxID=2608629 RepID=UPI00123D2702 --eELEKTIQAQIDSIDGTVAVAFYSLSKPKDSlLINVDEKFHAASTMKVPVMIELFKQAS -QGKINLQDSIVLKNESIVDGSLYRYNQIGSKVALKDLMHSMVTISSNLATNVLIELV-DA -KKVTASMRDLGAENIEVLRGVEDLK-AYEKGLSNSTTAKDLMVIMKSIANNSAGTPKDCE -AMITILKDQQH-KSLIPFYLPEEVKVAHKTGSIT-GVHHDAGIVYLPDGNAYVLVLLSKN -LK-DIDKGTEQLARISKTLYDY- ->[subseq from] Beta-lactamase n=1 Tax=Photobacterium damsela subsp. piscicida TaxID=38294 RepID=A0A1V1VGR3_PHODP ---ALVNIIKQQEKALNGTIGIAVLDTDSGSVW-NYNGEMRFPMMSTFKSLACAKLLADSD -KDKLALTHQVVIKKSDLVTYSPVTEKWVGKRFTPKQACDATMTFSDNTAANIVLHAVGGP -EQLTEFLRRVGDSTTRLDRTEPTLNEAKLNDPRDTTA----------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella flexneri TaxID=623 RepID=A0A2Z6A9I9_SHIFL --------------------------------------------------MALAAVLKQSV -TQKQQLNEPDEIKPADMVNYIPIAEKHVNGTKTLAELSAAALQYSNNTAMNKLIAELPGP -GGVTTFARAIGHETFRLERTKPTLITAIPPDPRDTRTPRAKAQTLRQLTRGHTLGETQRP -QLVTWLKGNTTGAASIRAGLPTSWTVGDMTGSGAYGTTNH-------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Gynurincola endophyticus TaxID=2479004 RepID=UPI000F8EC8CE ------SSIQQILDTAQGQFAVAYKNLTTGETV-FFNEDSVFHAASTMKTPIMVELYRNVS -DGKFTMNDSVLIKNESIVDGSIYQYQRVGTSTTLYELTKEMIITSSNLATNILIEWV-KP -EAIKQTLAAAGIEDVKVLRGVEDGK-AYRAGLNNTTTARGMMLFFEALYENKFTTEAYTK -EMIDILGEQKF-NEIIPAHLPDNVKVIHKTGSIT-GVVHDAGVVILPDGTSYCLVLLSKK -LE-DSEKGKATLANISKILYEH- ->[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=UPI000DF32A90 ------------------------------------------------------------- ------------------------------------------------------------P -QRAEAVRRALALPAGALRTDIDTAYADYYAEGHNSATLAGYGAMLERLVRGELLSPASTD -RLFKAMKFGTRGSYRLEAGLPKSLPLIHKTGTQHR-RACHVGVVQPQDGDATVLAVCAAD -LD-EQRAAGRLFEAVGRAIA--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. BL4 TaxID=2478710 RepID=UPI0011C3E7D4 -------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDRVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---ETGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. 15K316 TaxID=2530376 RepID=A0A4R4QQU4_9ACTN ------GQLQQVVDASTANAGVAVRDLSGDQQI-AVNGAFRPKAASVIKLWILVELLRRVD -CGQVSLDKGVLVTPAQVVDGTGELQHETFPQVTLYRLAEYMIKYSDNTAANVLIDYFGGF -APVNDLTDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSQ-VAVAFLTSG -PM---AGGDETVRRLARTVYDY- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides pyogenes TaxID=310300 RepID=UPI0011E40F60 ----LTDSISQIVSACPGEIGVAVI-INNTDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NREVSLGTLVNINRDKLDPWSPMMKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYANYTSPLGAAMLMNRLFTESIISDEKQN -FIKNALKECKTGTDRIVAPLKEGVIIAHKTGSGYNGAHNDVAYICLPDNVCYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0ADJ0_9CHLR ---NLTKQLTEIIAASGATMGVALHHIESGEEI-NLNADESFPMCSVLKIPVLVEAFRQLR -QGKFTLEDRWELTTAEKNIGSGILTYMQDGLPTVRDLLTLMIIISDNTATDIVMHRL-GV -EQIDRTMHELGLADIHMALTIRGIFDFSSGPDNNVSTPRDMTRLLAMIFRGEIIDRAACD -EMLYILLQQQL-NARLPLFLPYGIPFAHKTGTLA-GIRNDAGILYCSDESHVAITVFARW -DTEAVKDD--------------- ->[subseq from] Serine hydrolase n=1 Tax=Niabella ginsenosidivorans TaxID=1176587 RepID=A0A1A9I484_9BACT --qAVNQQIRDSISRSGASIAVAFKDLQTGNTL-YINEKKTYHAASTMKFPVLIELYKQAA -ENRYSLTDSLVLNNSSIADSSRYSYRKLGRKIAIKDLAYLMITKSSNLATNTLIQLV-RP -AGIMQTLRQLGANDTRVLRGVEDQK-AYDKGLNNTTTAFDLALLYEQLAKKELVSEKADQ -SMIKILMDQQL-NEVIPALLPENVKVAHKTGNIE-GLQHDSGIVFLPDGRKYVLVLLSTF -RPDQTRDAISTLAHISKLIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Larkinella sp. BK230 TaxID=2512173 RepID=A0A4R8CXP5_9BACT -------HLTTYLKKLTAQVSVAVEELAGKTTF-YHRADDLPPAASVIKLPIMVETMEQVK -AGQFDLDKIHLLQDAEKTGGSGILQTYPAQSLTNREVLTLMMTHSDNTATNILIREL-GM -DKINQRMRSLGLMQSVLNRLMLDTLAVKQG--------REMNALLKKIYRREVATPALCD -QMIEILKGNRD-QKTFRMFLPPSTVIAHKTGELTY-VRGDVGIFYVT--KPFLLSVFVQG -VS--TQEAERMIGEIAQLCYNQf ->[subseq from] serine hydrolase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=UPI00105E5EBB -----ERQVERRILAAPADVAVFFRLLGGEAEW-SYQPDVTFHAASTMKVPVMIELFHQAH -QGQLTLDDPLPIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR -QMVEILKRQHI-NDSIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYGP--QPFVLVILVRG -MAN-SKDSSALMADITRAFYR-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=UPI0008A985F6 ----LLERLQAIAAKQNGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE -RGDWGLDTRLALVANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-GL -DALNGLVRELVPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLATGQALGNEQTA -YLLEVMGRVKTGTQRLIAGLPEDARLAHKTGTQR-ARICDSGLIQTPEREPVLIVACVEG -E-PSLAKAERALRQVGEALT--- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Desulfosporosinus acididurans TaxID=476652 RepID=A0A0J1FKW2_9FIRM --dKLTRDIKKIIQNERGSYSISYQDTISNNNL-VINP-QKMTAASMIKLFVMIESYNQIN -EGVINENEEITLTSSMKVGGTGSLSSRKDGTLTIDQLIYLMITQSDNTATNILIDRI-TM -DKINTTVQKLGCLDTVLQRKMMDFKAQ-GEGKENYTSAADLCNILTKLYKNECLGEKYDP -MMIEILKRQEN-NTKIPLLLPAGTVVAHKTGELDK-VENDAGIIFTPKGA-YVLCVLSSG -IVA--GDARTIIAKVSKVVYN-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. CHY01 TaxID=1844116 RepID=UPI0011163515 --kALEDQIFRIIDQAGGAWGVVIEDLHTKEKI-EHQPDVRFFAASLIKVPIMTAVFADVY -AGKYAFEDRLSLRQEDLVGGAGVLQHLQPGLLSIYDLVMLMIIQSDNTATNILIDQA-GR -DSIRAIMDKTGMVNSQFYNKLMIIPAELEG--RNEVTAGDMASILRHLAHGSVISYDSCL -RMIDILKRQQL-RDALPLLLGPKWELANKTGTVT-GIEHDTGILYTGQSA-VLISVLTKD -AT-DSLTAKRAIGEIGKLVYEAy ->[subseq from] Beta-lactamase n=1 Tax=Archangium gephyra TaxID=48 RepID=A0A0G2ZQW0_9DELT -----RASLQEIAQVKGATVAVAYQHLGNPRDSlFLEADRSFHAASTMKVPVMIEFFRQAD -AGKLSVGQELTLANQSIVDGSPYAYERLGKPVPARELVERMITRSSNLATNTVIALV-DA -KRVTKTLRSLGARQMTVLRGVEDGK-AYQKGLNNSATARDLATLMTAIEQGKAASPASTQ -AMRSILLAQEL-NLEIPAGLPPGTPVAHKTGQIS-GVLHDAAIVYPSGRPPYVLVVLTSG -IP-DEKVARSLIADLSRQVFA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3N577_9ACTN --------LSQVVDASTANAGVAVRDLSGDQQI-SVNSTFRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPAQVVDGTGELQHETFPQVTLYRLARYMIKYSDNTAANVLIDYFGGF -APVNDLIDSMNQRETILARKMLDTEAA-MRGEENYTSPDDVVALLGAVWDAQILTPATRD -LMIGFMAEQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGA-QVAVAFLTSG -PI---ATGDETVRRLARTVYDY- ->[subseq from] Putative Extended-spectrum beta-lactamase PER-1 n=1 Tax=Candidatus Sulfopaludibacter sp. SbA4 TaxID=2043165 RepID=A0A2U3K768_9BACT --kRLESNIQRVTQSVNATWGIYIKCLETGEEI-ALNADQQMDTMSVIKIPLMAEAFRQME -AGKFALTDRIALTDAAKQPGTGIIRSLDAGVLTIKDLLTLMIIVSDNTATDLIYDKVGGP -EPVNKLMAEWGLNSIHATGKADAWFKRAGKTPFGLSSPRDMGKLLEKIEKGEAVNQKSSD -LMLQMMRGQVY-SSRLPRYVS-GFRIPHKTGDFLPYIGNDVGVLESPSR-RIVMSVFTAN -HFGAGDRLEDAIGRIAELTGNYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium MalM25 TaxID=2527998 RepID=A0A517TJT3_9BACT ---ALAAALGPMLESHQGEVTVAVKHLKTGRTY-LHNADKPMSSASLIKAPVMLTAYRLAA -LGQLSLDDPVTLREEDKVPGSGLLTPHFSNGVPLRDVIHLMIAWSDNTATNLAIEAIGGI -AETNDLMEKLGYENIRLNSLVYRGDTTIAPDRSGLMSAAETLDLFEKLAKGDAVVEAYRA -EMLDHLRACQY-NDMVPRYLPKGTVVAHKTGGVSN-ARCDAGLIESPTG-LIAYCVMTDE -NAEEDAAPHVLIAQIGKAAYDYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Planctomycetes bacterium MalM25 TaxID=2527998 RepID=A0A517TJT3_9BACT ------------------------------------------DPASTTKIMTAHLVCRLAQ -QDAKVLDEVVTFSERADKTSGSTADLREGEQVSAGELLYGLMLPSGNDASVAFAEHFGGD -TPYDRFIAAMNAEARRLGMNETGYRNTGLTAEGHVTSARDLVKLAHAAMQDGTFREVVAT -RRYATTVSSTTGYQRTDQLLKREGFYGVKTGTTGPAGACLVSAGER-DGKPLYVVVLGAN ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QS_3_64_15 TaxID=1919105 RepID=A0A2T2U1Z5_9BACT ---TLEEDVRAVLDTVEGDFAVAFRSLDTSQTL-LINEHQTFHAASTMKTPVMIELYRQAK -GGRFDLDDSIRVENESIVDGSTYSYEHLGEQRSIRTLMREMITASSNLATNILIEKV-GA -ERTTQTMRRYGADRIQVRRGVEDMR-AYRRGLNNETSAHDLMVIFERLARGEAVSEEASQ -EMIQILKGQEY-DDMIPARLPDAVEVAHKTGWIT-GLHHDPGIVFVPDGPTYVLVLLSQN -LE-DEDAGVTAFARISRLVFD-- ->[subseq from] Uncharacterized protein n=3 Tax=Bacteria TaxID=2 RepID=A0A1J4VCV4_9BACT ----------TIAQKRGVRIGFVIKDLKTGRTL-LRNENARFASASLVKIPLLITLYRDIT -DGKIKVLQGAYYSEKLRASGSGRLKSEPANRINLRDLVFLMLQHSDNTATNILADLV-GY -DHVTRYCRTMGWRNTNFVRPVMALELR-AKGIENWTTPKEFSEIIEKIFRGSMISQEASR -EMIQFMTNPPI-DDRLPRYLPPRIDIVHKTGLIYD-NAHDVGIIYLPGDQAVLVSAFADN -IGTNYMTAKETIASIARIIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Niastella vici TaxID=1703345 RepID=A0A1V9FYS2_9BACT --nKLQDNIKSKLAEQPGDFAVAFKDLSTGETI-LINEQQYFHAASTMKTPVMIEVYKQAA -AGAFSLNDSFVLKNESIVDSSVFSYQHLGEKRSLYNLVYEMIIRSSNLATNMVIELV-NA -RQVTQTMRQLGASHIQVLRGVEDSK-AFDKGFNNVTTAGDLQVIFEKMATGEIVDSASSQ -AMINILLNQQF-NEIIPARLPSTVKVAHKTGNIMH-VQHDSGIVFLPDGRKYVLVLLSKN -LQK-EDQAIKAMAEVSEMIYKY- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum odellii TaxID=2290917 RepID=A0A398DEV0_9BACT -----------LEYSQRVDVGIGFKDLKDGTEI-FYNGEKEFPLASVFKIPVLMTLYKQQE -LGILSIDDYYTIEEKDITRGSGVIKELKPGVMTLRDIAILMMIISDNNATDIIIKLV-GK -ENIKKTLEAIGVTNTIASVTTKDLKKPLNVKESNYSTPRDMIKILESIYKNTYLTRESCD -GILDIMKKCQTGLNRIKKYLPFGVKIAHKTGSLSINVVNDSGIIFTRQKD-YVLSVFVTQ -YNTEV------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 40-81 TaxID=1895835 RepID=A0A1M3QU06_9SPHI ---TLRKKISDIFSQFGATFGIAFKNLNTSATF-FWNAEDIFHSASTMKTPVMIEVYKQAA -QGKFSVTDSMLVKNSSIVDGSTYSYLHIGKKLPIRDIVFRMITVSSNLATNNIIELV-GA -KNVTATMRSLGTKNMLVLRGVEDKK-AFEQGLNNITTAYDLMLVMESIAKGTVADKKSTD -DMIDILLHQRF-KRVIGGKLPAGVKVANKTGAFK-GVRHDSGIVFLPDGRKYVIVLLSRG -IE-DEEKSAAALAEVSRLVYE-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella intermedia TaxID=28131 RepID=Q8KT53_PREIN ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRWFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3QWR2_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVTALQRVLNVPASALTRDFDEAYARYYRHDNNSATLEGYGAMLEKLVRGELLKPASLQ -RLNDGMKLGIYTNYRLQAGLPRGVDFIHKTGTQHR-RACHAGVIRPKDGAQGIVVVACTA -DLDEQKAAGPVLQRVGQAVTQ-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535JH70_9CHLR -------VVARILQTTARGVGVYYRDLTTGDSL-TVGSDGRFHAASTMKIPVMIQLFRDRD -AGLLSLDDSIIVTNTSLVDSSPYQYKRLGQRASIRELIELMETVSSNLATNLLIAKV-DA -KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGMLLAAIANGTAASAGSCR -DMLAILGRQHF-NEGIPAGLPAGTRIYHKTGWIGQVVYHDAAFVQPQGGRGYVLVVLTGG -IQKD-DDAHALARDVSKLVFDAw ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A359KKG3_9CHLR -----EELVTTIEQASGGTVGIAVAG-PDGNRW-SHNGQRQFKAASTVKIPLMIEIYRQID -RGERSLDERHVLSAIEKAAGSGVLLHHDGIELTIDDLIYLMISISDNTATNMLIDLA-GM -DAVNATMLELGMSMSTLARKMKGRP-AIEGEQENLATPDDYVAIVDAIFGDRATSTAARE -AMVTMLSRQQN-ARRIARYLPADLRWGSKTGSIA-GVTNDVGFVETPVGR-MILAVFCEG -FP-DQHDGEYAIGELSRAALH-- ->[subseq from] Uncharacterized protein n=3 Tax=Erythrobacter sp. QSSC1-22B TaxID=1860125 RepID=A0A1A7QE17_9SPHN -------------------------------------------MASTFKIALAMCILQLID -HEKVALDQMVEISADLLVPPPLIEPRHIGLAISVANLLDIMMVTSDNSATDALLKLVGGP -DYVSQAIAKANIAGMRIDRSTSQFLANYDDDERDNASPAAMAKLLAKLWHGNLTSIASRD -RLFEVMERCEN-DNRIKGCMPAHVTIAHKTGTLG-GSTSDVGVIELPEKGSVAIAIYIKK -SASPVIIRERAIAHASRAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Tissierella sp. DSM 105185 TaxID=2607614 RepID=UPI0012B1E36D ------------INNIDEDISIVIKDLTKNQWIlKYNERDVFPSASLIKIPIMVEMFYAIQ -NGEYKLEEKINIQENSRVPYSIISELKLS-EYPLIDLITLMIILSDNTATNVLIDLL-GY -DRINESIKRLDCNDTVLRRKMMDFQGARE-GRENMTSPMDMAIIMEKIYRKSIVDIESCN -IMMDILARQKY-RDMLPRYILDEVTIAHKTGELS-GLNHDIGIFQLENI-HYLIGIFTRN -GK-DDLEGKRSIGRISKLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI001302476B ------------------------------------------------------------- --------------------------KYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=1 Tax=Rufibacter roseus TaxID=1567108 RepID=UPI00082EBE37 ----LREQITTELNKEAGTFAVAFKDLQTGQEL-LINEHETFHAASTMKTPVLIEAYKQAA -EGVFSLQDSILLKNESIVDGSAYTYANLGKKWPLADVLYKMIIHSSNLGTNLVIEKL-DA -KKVTQTMRDLGAKDIQVLRGVEDGK-AYEQGLNNTTTAYDLMLIFEKIAKGEAANAKASE -EMVKILLDQKH-KNIIPANLPKEVKVAHKTGWIT-GVRHDSGIVFLPDGRKYVLVLLSKG -LK-DDKAGISAMANVSEIIYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6L6N5_9BACT ----LNEELERLNDQSKARIAVAVHDLESGWRF-SLRADRWFLAASTIKVALLLAVFRAAD -ESRLRLDDSLHVRNRFFSAGSPFHYQAIGRTAKISALAQGMISASSNLATNLLLDLV-GV -EYARKVLRDAQVDGVELRRGVEDH-AAHERGINNEVTADGLVRLLSAV-RGDFLSKESKE -QAIRILLEQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -AS-EQDGRRETVAAISEAIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A4R5WX81_9MYCO -----ERQVERRILAAPADVAVFFRLLGGESEW-SYQPDDTFHAASTMKVPVMIELFHQAH -QGQLTLDDPLPIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAAGKVVDPDASR -QMVEILKRQHI-NDGIPSGLDRTIPVAHKTGTLK-AIHHDAAIVYGP--QPFVLVILVRG -MAN-SKDSSALMADITRAFYR-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000D0AE8CF ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDTYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase (Penicillinase) n=3 Tax=Xenorhabdus bovienii TaxID=40576 RepID=A0A077MT10_XENBV ------------------------------------------------------------- --------------------------------------------------MNLLLGQLGGA -HSVTRFARSIGDNAFRLDRKEPELNMVTPGDERDTTTPQAMADSLYKLALGNTLAATQRT -QLVEWLKGNTTGGTSIRAGVPDNWIVGDKTGRCNYGSTNDIAVIWPDDKAPLILVTYFTQ -PSKDAKAHNDVLAATARIMTQ-- ->[subseq from] Serine hydrolase (Fragment) n=16 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6B5GLX8_STAAU ----HAKELNDLEKKYNAHIGVYALNTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIA---------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Rudanella sp. HX-22-17 TaxID=2614655 RepID=UPI001262410E ----------------SVRVSVALETLADSSVRlYHRADERVPAASLIKVPIMVEAMVAEI -EGRINLDEIHILLDSEKVGGSGVLKDYPNRSISYRDLVRLMITSSDNTATNILIGDL-SP -EAINARMRALGLPQTGLNRVMMDTLAA-RQGRENVVTAREMNHLLIQIYRHRVATPALCE -QMLDFLKANED-TLTIPSRLPRQLVVAHKTGTLSY-VRADMGIVYGP--RPFVLSVLVEG -AD-SEAAGEAIIAQIARLAYS-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetales bacterium 71-10 TaxID=1895807 RepID=A0A1U7GQB6_9BACT ---ELAAKLDELAKAHKGKVAIALKNLKTGESY-ALNAETPMPTASLIKFPVMIEAYRQAA -EGKVDLNAPITLRKKDMVPGSGVLTYHFSDGFPLVDAVHLMITYSDNTATNLVLDAI-GI -GSTAATMEKMGYPNTKIHSKVYRRDTRSKVYGLGSTTAADMVKLMDDLHAKKLVDEKASE -AMYKHLLTCDD-KDKFPRLLPPGAKVAFKTGSVDE-SRTCAGVIETKGG-PVALCVLTTD -NEDQENAGNVLCAKAAKEVYDTf ->[subseq from] Serine hydrolase n=1 Tax=Rhodoferax koreense TaxID=1842727 RepID=A0A1P8JQ86_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -KRFDTLVRTMGVDKAAVRKTIDEAYARYYAKGANTATLEGYGGMLEQLVRGKLLSAEHMK -LLYTDLKFDTYDAYRLEAGLPRTVKFIHKTGTQMH-RACHMGVIDPQDGGRAAIVVATCA -EGDEHAEAGRAFEQIGRAITQ-- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A4Q0J4G6_9BACT ---ELESRIGRYIADKDARIGVAVI-IDGCDTA-EVNGSQFFPMLSVYKFPQALAVAEHCR -RHGVGLPDTVRVSADEMKSWSPMRDRFGAVNLPLLALLEYSLQQSDNNACDVLFRMIGGP -AVADSLMNKWGYGDIRIRSTEDEMHRDTDLCLVNCCTPLEMARLLDDFNTGIRLRSEENR -AIASLMESCVTGRDRLARPLTTPAILGHKTGTGDVDAVNDAGYVNLPDGHRYAVAVFMAS -SAYGLEDTSRMIADISEIVYS-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A357N964_9FIRM ----LRKKVADVLSAYTGRWGIVIANAATGDRL-ELNPDMIFPAASMIKVPIMYEIMRQAA -AGKLSLDAALRINDEDKVGGAGILKELQAGKFTVRELVTLMIILSDNMATNMLIDLI-GT -ETVNQTAAELGLKSTVLRRRMMDFAAA-RAGKENQTSAADMALIFAKIHTSAGLPRAYGE -LMLDILGRQQI-QDKLPFYLPGGITLAHKTGTL--------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7WDH3_9BACT ----------KIRKEHGETLGISFYDAQTTIQW-SFNADHYFHAASTMKLAVLLAVFRQIE -RGELTLDAPVHVRNRSIVNQEPFMYGHLGKTLAVRELAYWMITKSSNLATNLLVDVV-GI -ATIQHALDEMEIDGVKVLRGVEDQ-AAFDAGLNNEVTANGLLKLLRLVAEGKAYSKQSSE -EMLNIMLEQQY-RSGIPAGLPKAARVAHKTGNIST-VHHDAGIVFLEDRKPYVLVILTQF -GAE--TARGTAVAEVSRDIYN-- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter certesii TaxID=228955 RepID=UPI00041B7E6F --eRLKKTIKTQIDTIDGTVAIAFYSLSEPKDSlYINVDEKFHAASTMKVPVMIELFKQAN -EGKINLNDSIVLKNESIVDGSLYSYQQIDTKVALKDLMHSMITISSNLATNVLIELV-DA -KKVTATMRELGAEKIEVLRGVEDLK-AYEKGLSNSTTARDLMIIMKSIANTNAGNQKDCE -AMIAILKDQQH-KNVIPFYLPKEVKVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LK-DFDKGTVQLAKISKTVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea turkmeniaca TaxID=103838 RepID=A0A5S4FJ25_9ACTN --------FETLFRMAGVTGWLYAADLDSGREV-GHGADEQLPTASMFKVPLLVEFCRQAD -AGLLDPTSRVTVTAGDRVPPTGISAMLDDVTISLRDLAYLMIAVSDNSAADVLLARV-GM -DAVNAMLARYGLGSTRVSQSCRELNESLDPARANRSTPREMARLFGLIWRDEAASVASCA -WMRTVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369I995_9BACT --eRLKEAIQAKLAGVEGNFAVVFKDLQSNQTL-FINEKENFHAASTMKTPVMIEVFKQAK -GGKFRLTDSILVKNESIVDGSAFSYKMIGKKMTIYDLTYQMIIVSSNLATNILIDLV-DA -KKANATMRDFGANDIQVLRGVEDSK-AFQLGMNNSVTAYDLMVIFEKIARKKAIDPTSSE -GMTRILFDQKF-NEIIPAKLPKEVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLVLLSKN -LK-DPKAGVRILADVSEMIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644V629_9ZZZZ --------LNNVIAQSGAACSVYYKSLTTDQVF--YNYSGKMPAASLIKVFILAEAMDEVK -AGNYKLEDEYKIDVSDIVEGSPALQNRQAGTISFGTLLEKMITVNDNTATNMLIDIL-GM -DTINEYIQAKGYEDTVLSRKMMEVEAQ-KAGKENYTSVNDLVNIFERLYNNKCVSAEYDK -KMLQLLKQQKA-NNKIPALLPKNITIAHTDGDLP-GVQNDCGIVYAKEN--YILAIMTDG -SI-DKGKTLKTINQISSIIYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E9NKC2_9BACT ------------------------------------------------------------- -----------DVTAADLHPGSGTLSPLLAQPLSIRNLMELMLRISDNSATDMLLARAGGS -EAVTARMRALGIDGIRVDRPTALLIAEFDLDPRDTATPNAFAELLARLHRGELVSEDSTA -LLLDIMERCLTGENRLKGLLPADTVVAHKTGSLA-GTANDVGIMALPDSGHVAIAVLMKS -SDRSGTDRARAIAEIARAAYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Aminicenantes bacterium RBG_13_59_9 TaxID=1797268 RepID=A0A1F5B2Q7_9BACT ---SLRKAIKAEIGQSGAEVSLAFKDLQTGDTL-FIREKDMVHAASTMKVPVLIEVFKQAE -EGKFRLDDRIVVKNESIVDGSPYSYGLIGKSLTVRELAERMITVSSNMTTNILIELV-KP -GSIMSTLELLGIRRMRVLRGVEDGK-AFEKGWNNQTDAFDLLKVMESIASGRAGSRASCR -EMTLILEKQKF-RGGIPAGLPPGIGIANKTGSIS-GMEHDAAIVFPPGRKPYVLVVLTRG -IK-SSEEGEKLISRLSRLIY--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. mrc49 TaxID=2054913 RepID=A0A2M9NNM1_9BACI ----IENDILALVDAFDGNIAYKIES-GFGDMI-GYQEEDSFQSASLIKIPMIIEGYRQSE -RKNIYLNQPVTIPPNAVTGGSGVLHALSNKVLTVEDLLTLMIMVSDNTATNMMMSLL-GF -DEINRCIQELGLKNTILGRKMQDFKA-LKEGRDNTISAEDTITCLKAIHTGDFLTKESQE -RILRVFDNQQL-RDKLPSLMGRGVKVASKTGGIR-GVSHDCAIIRSETQT-VYAAVLTEN -M-KSEEESRQVISKIGKLIYDH- ->[subseq from] Beta-lactamase n=2 Tax=Lactobacillus saniviri TaxID=931533 RepID=A0A0R2MTU5_9LACO ---AVRAEINRYITPLAGTNSVYVTPMNASQPL--VINNRPQRAASTIKLFILATAYAKVS -RGQFNLDQHYTLQETDKVGGTGVLGGQAAGTLSYRDLLNDMITQSDNTATNIIINLVGGM -PAVNAEIRQLGARDSQLNRKMMDTAK-LTAGVDNVTSVQDVGHLLQRLYRHQLLSADADT -QMLNILQRTQN-HSKLPASLPATATVYNKTGEFDYGVQNDAAIIADKKGA-FVAVVMCQN -GNE--AAQISAMRQLGSALY--- ->[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A161QFR4_BDEBC --kTFEESLKELEAKQPIQLGVFVKNLSTGEIL-SYRGDDLWYVASGVKLPIVLENLRQVD -QKKYTLDSQIELRKEDFVDGAGYTNSKKAGSLSVKFLMEQAIIYSDNTASDLLIRQA-GL -ESVNSCVQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK -FLIDTMTKVQTGQRRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGIVIAACVKD -FE-SLDMAESALRSVGTVL---- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides xylanisolvens TaxID=371601 RepID=A0A412K4L1_9BACE ----LTDSISQIVSACPGEIGVAVI-INNTDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NREVSLGTLVNINRDKLDPWSPMMKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYANYTSPLGAAMLMNRLFTESIISDEKQN -FIKNALKECKTGTDRIVAPLKEGVIIAHKTGSGYNGAHNDVAYICLPDNFCYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. R2A2 TaxID=2213057 RepID=A0A2U9NHF9_9PSED ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARKLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGRAIS--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=Q8RTD8_KLEPN ------------------------------------------------------------- ----------------------------------------AAXYMSDNSAANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASKRGARGIVALLGPNNKAERIVVIYL-- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Clostridium disporicum TaxID=84024 RepID=A0A173XE44_9CLOT -----YKTVSNILSKYDFNYSIIFKDLSSSETI-SWHYNSKFPSASTIKIFIAIEAYNQIN -KGIIFEDDVILIEDNMKVGGSGIISKYSKNLISIGKLIYLMMTESDNTATNILINIL-GM -DNINVMIKKLSINNSFLNRKMMDFN-AIKNGFDNYTCAYDLATVLEQLYKNTCINEHYDN -LILSIMTNCRN-NSKIPSRLPSKIKIAHKTGELDY-IENDAAIVFTPYGD-YILTILTEG -LD--NEKEIKIISEISKIIYDSy ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacterium celere TaxID=225845 RepID=A0A366IIY6_9MICO -----------------------VWGTHQGRTV-VHDPTTRIRMCSTMKLPLAALTLRESA -RGGLDLDTVLTWTAEDLIGHSPFTREDEDSTATIAELAEAAARGSDNTAANLLIDEVGGL -PALNAYARDLGDRVTRFDRYETEMNEL--SGELDTTTAASFAALALEA--VGQLGPDDRR -TLFSWLPGHD--DRRIGAVVPAGIDLVHKTGTSGDGVLNDVAIMHDDAEVVGGLAVFTDC -PSPS----EEVVVEIAR------ ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax sp. Root219 TaxID=1736493 RepID=A0A0Q8TDC6_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -KRVDALARTIDVATTDLRKTMDEAYQRYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ -RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA -EDDEHGEAGRAFEQIGRALTQTf ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas zhaodongensis TaxID=1176257 RepID=A0A3M2HYF0_9PSED ---DFLERIAKVDEQTSGELGVYLKDLDSGVSA-SYHGDEVWYLASTVKVPIAIAIMRRID -EGTMSLDTTVRLMESDYVDGAGPTNSHKPGTLSVRYLMDQMLIHSDNTASDLLISLV-GL -DAINAVTAELVPQGFGPITRLADVRRRYYATPFNSATLQAYGDLLSALIQGRAASRASTE -YLISVMNRVETGTQRIKAGLPKTVGYAHKTGTQVS-RICDAGLIAPPPAGQIVVVACVRG -G-ASTAKAERALRGTGEAIT--- ->[subseq from] serine hydrolase n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=UPI0009BE8C9D --kTFEESLKELEAKQPIQLGVFVKNLSTGEIL-SYRGDDLWYVASGVKLPIVLENLRQVD -QKKYTLDSQIELRKEDFVDGAGYTNSKKAGSLSVKFLMEQAIIYSDNTASDLLIRQA-GL -ESVNSCVQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK -FLIDTMTKVQTGQRRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGIVIAACVKD -FE-SLDMAESALRSVGTVL---- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H2I8_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVRRALNLKPAELQRTMEQAYERYYARRLNAATLEGYGAMLEKLVRGQLLSPAGTR -RMFSDMKLGIPTNYRLQAGLPRDLPFIHKTGTQHR-TACHAGVIEPENGAEAIVVVTCAA -DVDEQKEAGRIFERVGQALT--- ->[subseq from] Class A beta-lactamase n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A3N2M6K9_9BACT ---SLQNELTSFVENKDARIGIAVI-INGKDTV-SVNGSKDFPMMSVFKFPLALAVAKWVD -SNGMSLNDSIAFGPKALIKYSPMLKKYGSGLMSFKELLEWSLIESDNNAADLLLKRVGGT -ACATTLLKDAGELDITIGASEQNMHQDPYTSYLNRSTPLAMATLFDRFDTEIKNRSKSFS -DISVMLEQCRTGLDRLAAPFATNAIVGHKTGTGFISAINDCGYIHLPNGTQYTIAVFVAD -SAYDMTETSKIIADISEIVFK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingorhabdus wooponensis TaxID=940136 RepID=A0A426RTZ8_9SPHN --eKLTADIDSYWKKFPGRSGIAIYTPFSEEII-GKRHTERFPQQSVSKMWVALTILEQEA -SGKLSLDKRIRVSREDVVVFSQPLKNYLDGRMPLRELLAHSINASDNLANNVLLRVAGGP -QAINQMLERRKIQSIRFGPGEVLLQSAYLESPLDGAAPGTIALVLKRFSERDANDPG--A -KLLKLMAGTYTGRSRLRSGLAPGWRLAHKTGTGQATAVNDVGVMKAPDGCVYPVAVMVAE -TRAGTQATNALMQNVALAVIRH- ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Spa11 TaxID=2528022 RepID=A0A518K6U5_9BACT --qALGKALRPMLEGHQGAVTVAIKHLETGETF-TFDADRPMPSASMIKLPIMLTAYRAEL -RGDLSMDDKLELKESDKVPGSGLLTEHFTPGLTLRDAIRLMMGWSDNTATNLVIEAIGGI -RSVNRLMEGLGYDNMRLNSLVFRGDTTIAPERSGVMTAAETIDLYEKIVKDEDEIEEARK -EMLDHLRACQS-KDTLPRLLPKGTTVAHKGGSVS-ASRCDGGVIESPTG-PIAVCVMTTD -NKDTEAEPMTLIAQVGKAAFDYf ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Planctomycetes bacterium Spa11 TaxID=2528022 RepID=A0A518K6U5_9BACT ----------------------AIADGETGKLLwGYNDAGTRDPASTTKMMTAYVVLKIAE -EDPKVLDEVITFSERADKTGGSTSAVKAGEKVTVRELLYGLMLPSGNDASVAFAEHFGDE -SAYDRFIAKMNATAKELGMDGTGYNTHGLTAEGHVTTAQDLVKLAHAAMQNELFR----- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. MES3-P3E TaxID=2058321 RepID=A0A2N1APX6_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -QRAQALARALGVRTESFTQDYDQAFDAYEATGENVGTLRAFGDLLASLHGGDDLSAEQRQ -TLLAVMQRTSSGKRRLKAGLGEGINFAHKTGTQQR-RSCDAGIAERATEGPWVIVSCTRG -PAA-VSAHERALASVGEA----- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=A0A4Q9QQE6_9PSED ----LLERLQAVAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAIAVLRGVE -RGEWNLDTRLILAANDFVDGAGSTNQHGPGALSVRFLLEQMIIYSDNTATDRLIRLV-GL -DAVNRLVSELVSEGFEPITSLADVRHHYYSRNLNAARLSAYGELLERLAEGEALGAEQTT -YLLGVMSRVKTGSKRIIAGLPADAHFAHKTGTQR-ARICDSGLIDTPARAP-VLVVACVQ -GESSLAKAERSLRQVGEALA--- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3B9YNN0_9BACT ---RMNAQLETEARRFPGRIAIFTKDLKRGWEW-SYHSDDLFPSASLIKVPVMIGVFEKIN -RGEMALGQQLQLKRRLRAGGSGSLKWSRDGILTVRQLLDHLIMESDNTAMRILIDEV-GI -GYLQRQFQRIGLVYTEIYPEGLSLSSS-RVRYENFTTAREMSMLMEKIYRGEMVDRFSSG -LMLEILKQKKA-PSRLAKHLPIGWQIAHKTGLLRR-ACHDSAVIFSPEGD-YLITVLTGQ -NT-DYSSAKDHIARLGAITYDHy ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=UPI0010385B88 ----LLERLQAVAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAIAVLRGVE -RGEWNLDTRLILAANDFVDGAGSTNQHGPGALSVRFLLEQMIIYSDNTATDRLIRLV-GL -DAVNRLVSELVSEGFEPITSLADVRHNYYSRNLNAARLSAYGELLERLAEGEALGAEQTT -YLLGVMGRVKTGSKRIIAGLPADAHFAHKTGTQR-ARICDSGLIDTPARAAPVLVVACVQ -GEPSLAKAERSLRQVGEALAQ-- ->[subseq from] serine hydrolase n=1 Tax=Marinobacter sp. JB02H27 TaxID=2597703 RepID=UPI001245D627 --tDLEQRLGEIDEDYPGELGVFVHNLKNDEKA-SLRADEPWYLASTVKVPVAMAVMETID -RKDMTLGTTVTLEPTDFVDGAGETNKSPGDKVTVQYLLEQMLIHSDNTATDVLIRLV-GM -EAVNELVAVNTDGGIGKVTTLADVRRSYYGSGLNSGRLDDFSILFEALAKNQVLGKSSRD -YLLSVLERIETGDNRVKAGLPEHVRFAHKTGTQHR-RACNIGLATVKDHP-GVIIAACGR -HTADLAASEKAFRQVGKAVAD-- ->[subseq from] Beta-lactamase n=1 Tax=Fimbriiglobus ruber TaxID=1908690 RepID=A0A225DJZ1_9BACT ----LEALIAPIAKEHHGKVAVGVKHLVTGESY-YLNGDDVMPTASLIKLPVMVEAYWQAE -EGKVKLDEQIVLKADDKVPGSGVLTDNFSPGLALRDAVRLMMTMSDNTATNLVLDKI-SI -PATGVRMEAIGLKETKIHSKVFRGTTTIDKKRSGSTTTKEMVQLLEKIHKGEVVTPKACE -EMMAILGKNQD-NEKLVRLLPPGTKVAHKTGSLN-AAKTDAGIVYLRDKPAFAICVLTNE -NQDQDNAAQLTIARIARAAYDHf ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium 24-56-14 TaxID=1970588 RepID=A0A258Z977_9SPHN --eTLRNDIDTLWKKFPGRAGIAIYTPFSDDII-GRRHTERFPQQSVSKMWVALTILEQEA -AGKLSLDKRIRVSRDDIVVSQPIKQYLSDKDMSVRELLAHAVNASDNLANSVLIRVAGGP -QAINQMLDRRKVQSIRFGPGEVLLQSKYLASPLDGAAPGTIALVLKRF--GERAPDDPGA -KLLKLMAGTYTGKSRLRSGLAPGWSLAHKTGTGQSTAINDVGVMKAPDGCRYQVAVMIAE -TRAGREVTNGLMQNVARAVVRH- ->[subseq from] Serine hydrolase n=1 Tax=Limnothrix rosea IAM M-220 TaxID=454133 RepID=A0A1Q4R6E5_9CYAN ------------AADPELDATLLFVDLDTGEYL-DVAASRSVSAASTIKIPVLVAFLEAVD -QGEVQLKEQLMITENVKGGGSGNLQYKDNGTFSALFVASEMSINSDNTATNMIIEQLGGF -ETLNLKFQRWGLKQTQLNELLPDLEGT------NQTTARDLAFLLAKINQGNILSTRSRD -RLMRIMSATSN-NRLLPQSLGQGAAIAHKTGDIGF-IIGDAGIVDMPNGKRYIASIFVER -PY-NAEKGRELLHQIGRQFYQY- ->[subseq from] serine hydrolase n=1 Tax=Acuticoccus kandeliae TaxID=2073160 RepID=UPI000D3E795B ---SLLAELARLGEGAAGDLAVAALHFASGRRV-LMNEAGHFPPGSAIKLPIALRVLERVD -RGEITLDTLVEVRPAEMNPPGGLGELFRAPGLSVRNHLEGMITRSCNTSTDVLIRVAGGM -AGVADWVARAGIGDFACTLTMREALCRFRHDERDLCEPRAMLELLRRLHARDGVSPAAAS -VLTDTMTRTVGTRDRIGARLPEGVATATKTGSGA-GTAVDVGFVELPAGGTLALAIFVMG -SRRDMATRNRAIADVARLVVDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561WCD0_9ACTN ----LTRQLAQVVAATNNRAGVTVRDLSGNQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQLSLDREVRVTRADVVGGAGKLKSEPIPQVTTHRLAEYMIEYSDNTAANVLIDQLGGF -APVNALIDSMNQRDTVLAHKLFDGGAD--RGEENYTSPDDVISLLGAVWDARILTEPSRD -LMIGFMRNQTR-NSKIPAALPPGTPLAHKTGDDTD-ASHDVGYCLTPGA-ETAVAFLTTG -PFRS---GSETVRQLARTVSD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XU06_9BACT ------------ERHALEKLGIAFWDSETTLQW-AYNADEYFHAASTMKLAVLLGVYREVG -RGELTLDAPVHVRNKSVVDDQLYMYRNLGRTMTVQQLAHAMIATSSNFATNLLVDVV-GV -PVIQTALSELGIDGVRVVRGVEDQ-AAFEAGINNEVTAAGLLKLLRAMVEGRAYGPDASK -QMLEIMHDQRF-RSGIPAGLPQAARVAHKTGNIAT-VHHDAGIVYLEKRKPYVLVILTQF -HHE--TPRGTAVAEISRDIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537KG71_9BACT ---SLKENIYQELSKQEGTFAIAFKDLSTGKEL-LINDTVTFHAASTMKTPVLVEVYKQAA -EGKFSLSDSLVIKNESIVDSSLFSYKHIGEKRTISFLLYQMIIVSSNFSTNLIIELV-GA -KNVSATMQQLGAKDIHVLRGVEDGK-AFEKGLNNTITAHGLMTLFEKIARGETVNPAASQ -AMINILLDQKF-NDIIPAQLPANVKVAHKTGSIT-GVHHDSGIIILPNGKKYVLVLLSKN -LK-DEKAAIKAMANVSKLIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A350UEZ7_9BACT ---KTLAAIADLDRSFDGAIGVAALDLTTGRTF-AYHGETVFAQASSIKIPILMRAFQAAA -EGRFSLDDQLTLTTKDTVGGSGQLQRLLESGLSIRDLLTAMMRDSDNVATNRAITLV-DM -ASVNRMLDELGFLNTRLRRIMIDSGAA-QRGLENVSTPLEMVRLVRLLHDGAFISPRASD -EMIAIMTLV---DASMRKAIPEEIRVASKPGGVP-GVQCETGIVYLRHR-PFALSVMSAA -APEGAP---NPVGAITSIVL--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. TaxID=1882945 RepID=A0A3E0RE22_9BACL ------PSLERLTEETGGQWGIYLEDVRTGERL-GIAEHQRFYAASLIKVPIMTAVFAEAY -AGRLALSDKLRLRREDQVGGAGVLQHFTPGTLTVYDAVTLMIIQSDNTATNMLIDLI-GT -DAIRTAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRFLATGKAISYNSCL -QMINILKRQQH-RDRLPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VIICALSKN -VD--AKAAGEVMGQIGRMVYDLy ->[subseq from] Serine hydrolase n=1 Tax=Gemmataceae bacterium PX52 TaxID=2598579 RepID=A0A5C1AJT5_9BACT ---TLASRIKPFADAHKGKVAVAVKNLATGEAF-DLNADEVMQTASLIKLAIMVEAYRQAD -EKKTDLGKMVTLAKDDKVPGSGILTSHFSDGFPLRDAVRLMIVYSDNTATNMVLDQI-GI -KPVNAMTAALGMPETRINSKVFKRSTRSEKYSLGSITAKDAVNMLELIHTEKAASPDSCK -AMLGHLKVCDD-KEKLTRFLPAGTVVAHKTGSTDR-VRTAAGIIYVPKTIPVAVCVLTND -NQDQDNAGQVMIGKIGKEVYDFf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9RFK5_9BACT ---DLQDKIAQIRSQFPGEMSIYMKNLDSGDEI-TVDSDKVFETFSVIKLTIAAELMHQVE -GGKFSLSDRIPLTAGDERLPSGVLYALDPGLPTVNDLLTLMIILSDNEATDILADKV-GR -ENITTYMHSLGLANTSIRYADLDWDRYDAGIYFGHSTTREIGQLLEMMARGKLVSKSSSD -RLLGIMEKQQV-NDRFPRYLK-DVRIAHKTGDGQPFIANDAGILWVNG-EPIVLVVFTGH -HRGTTASLHDAIARIAAYVVQYy ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A431MUE1_9SPHI --nAMEQQVKQKLAEQKALFAVAFKDLKTGKTL-LINEHQYYHAASTMKTPVLVEVFKQAA -AGKFNLTDSIMVKNSSIVDGSPFTYSYIGRKRTVYQLAYDMIIASSNLATNIIIELV-KA -ENVMKTMKELGANDIKVLRGVEDSK-AFEKGLNNTTTAYNLMLVFEQIAKRKLVSKKACK -EMIKILLDQQF-NTIIPAQLPANVKVAHKTGSIT-GIHHDSGIVFLPDGRKYVLVLLSKF -EGAE-EGPTTTMASVSKIIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Acidovorax sp. Root217 TaxID=1736492 RepID=A0A0Q8T1T7_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -KRVDALARTIDVATTDLRKTMDEAYARYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ -RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA -EDDEHGEAGRAFEQIGRALTQTf ->[subseq from] Uncharacterized protein n=1 Tax=Peptoniphilus sp. HMSC062D09 TaxID=1739305 RepID=A0A1E9APW9_9FIRM ----LNEKISSLLNNVEGEFGVYFEDIQDHNKV-MINENLIFCAASTIKIPLVALVLKEYE -EGKFDINDKVDIKLENRVGGTGVIRNLDKSFPTILNLINLALVVSDNIATNQLIDIVGGF -GKINEFNQSIGLNNTKFQRKMLDLKSL-NEGLDNFTTAKDLGTLLTLIAEGKCVSKKSSE -LIIKILKTQQF-RQKLPNFIPAVVMVANKTGDLWK-TQHDVGIFILPKGERYVVAVYSQK -LSED-YEGIEAISKISKIVYDY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=UPI000834FC4C ----IKKEIMTVLAGIKGKAGVAIEI--DNECF-YYHNEEVFPSASVIKVPILIEGLRQAE -NGTITLNDMLPIRE--RVGGSGVLQALSDQSMSVKDLLTLMITVSDNTATNMIIDLL-GL -DSINKTMETLGLQKTALQRKMMDFAA-VKRGLNNITCASDLIICLKVINEGEYLSEESRT -LALTMMNYQQFHDKLTARVDPDKVFVASKTGSLP-GVENDCAIFKYRGKT-AYAAILTEK -LE-DEYSGRQVISQIGKYLYDY- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. XJ-2 TaxID=2164099 RepID=UPI000D6BE052 --hKLTAKLQALAANFQGEAGIYVENLKTGRFV-AINADTVFPTASIVKVPLLVGLFDKIE -KGELKYHQPWTYRDSSKYGGSGIMQFFRDSATEVSVLAALMMSYSDNTTSLMIQSMAGGG -ARVNELMEQYGLKDTRVNSRTPGRAEIWKKYGWGQTTPREMARLVKMIRKGEIISPAASD -RMYRLMCRGYY-DESSLSQLPPYVQAAHKTGSVD-ATRSEVVLVNAPHGD-YVFHVATKN -NKSDDNEAVVFIRNVSAVIWNHf ->[subseq from] serine hydrolase n=1 Tax=Saccharomonospora sp. CUA-673 TaxID=1904969 RepID=UPI0009FA25AB ---DITGQLHAVETRFGGRLGVYAVDTGNGFAV-RYRERERFLMASTAKLPIVAATLGRGV -----PLDQPVPIRQEDVLEYAPVVAERVGQTMTVAELCDAAITQSDNSAANLLTAQVGGP -EHVTGFLRETGDRVTRLDRWEPELNTR--STSLDTTTPAAMGDCTRTLLFD--------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Pontibacter korlensis TaxID=400092 RepID=A0A0E3UUX8_9BACT --qQTERQLGELISRSPAITGLVAVDLTTGDTF-SFNADVVFPQASAIKVPILMSVYKQAH -EGKFTLSDKREVAATDVVGGTGILKDLVDLPVSIRNLGVLMITLSDNTATNSLIDLV-SM -QEINSMLRSLGAKQTLVQRKMINSAA-SGRGEENLSTPADAAKILQLLYKGEFINKTTSD -EIISILKKTDRQTSRLATRLPGHVPIAFKPGVLN-GVSTEWAIILLPER-PYAVAVMESY -KV--EGQAEHTVEELSEVLYQYf ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus mesonae TaxID=1193713 RepID=A0A3Q9QYH9_9BACI ----IKKEIMTVLAGIKGKAGVAIEI--DNECF-YYHNEEVFPSASVIKVPILIEGLRQAE -NGTITLNDMLPIRE--RVGGSGVLQALSDQSMSVKDLLTLMITVSDNTATNMIIDLL-GL -DSINKTMETLGLQKTALQRNMMDFAA-VKRGLNNITCASDLIICLKVINEGEYLSEESRT -LALTMMNYQQFHDKLTARVDPDKVFVASKTGSLP-GVENDCAIFKYRGKT-AYAAILTEK -LE-DEYSGRQVISQIGKYLYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coriariae TaxID=285665 RepID=A0A1C4V3N6_9ACTN -------------------SGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQASLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGDILSPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---DTGDETVRRMARTVYDY- ->[subseq from] serine hydrolase n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI001412FC36 ------------------IVSVTVLDKSGEVRY-AKNEKLRVPSASVIKIPVLIELSQQVD -EKRVKWKEKIKLHTEDRVGGSGDLQYEAAGKFTIEELAVKMIAVSDNVATNLLIDRI-GM -ENVNLGLENWGFDETRLNRKMMDFK-AIQEGKQNYITSFEVSKMLWGLLTKRILKDQSSK -KALEILLKCED-VTTIPRKIPKTVPVAHKSGTLDY-VRGDAGIIFS--REPVIVSVFVQN -FE-SQEQAEKIIGELAEIAYQTy ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA27(2017) TaxID=1932112 RepID=A0A1Q9Y9B3_9PSED ----LLERLQATAAKQDGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE -RGDWQLDTRLPLAANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-SL -DAVNALVRELAPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLADGQALGQAQTA -YLLAVMGRVKTGSKRIIAGLPKDAHFAHKTGTQR-ARICDSGLIRTPEREPVLIVACV-E -GELSLAKAERTLRQVGEAL---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127T5D2_9BACT -------AAQQAETELNARVGLAIHDTGSGNSW-QYNADERFPMTSTFKVLACGALLARQD -VGDEDLSRQVPISQSDLVTYSPVTETWVGQDISLAALCDATLRTSDNTAANKVLEALGGP -DAVTTFLRSMGDEVTQLDPWETELNEATP------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=UPI0012BA0800 ----LTRQLAQVVAATNNRAGVTVRDLSGNQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQLSLDREVRVTRADVVGGAGKLKSEPIPQVTTHRLAEYMIEYSDNTAANVLIDQLGGF -APVNALIDSMNQRDTVLAHKLFDGGAD--RGEENYTSPDDVISLLGAVWDARILTEPSRD -LMIGFMRNQTR-NSKIPAALPPGTPLAHKTGDDTD-ASHDVGYCLTPGA-ETAVAFLTTG -PFRS---GSETVRQLARTVSD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A165P2V7_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYAGQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVTCAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Gelidibacter japonicus TaxID=1962232 RepID=UPI0013D77FB0 --eKFEQNIQAQIDSIDGNIAVAFYSLSQPKDSlLINVDEKFHAASTMKVPVMIELFKQDH -EGKIDLQDSILLKNESIVDGSLYSYSQIGTKVALSDLMHSMITVSSNLATNVLIELV-GA -KNTTATMRSLGARNIEVLRGVEDQK-AYDQGLSNSTTARDLMIIMEAIANNTAGRQGDCE -AMITILKDQQH-NDLIPMYLPKEVQVAHKTGSIT-GVHHDAGIVYLPDGRTYILVLLSKN -LK-DFDKGTDQLAKISKTVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=A0A0E3UPZ2_9GAMM ---DLERRLQAIDAGLGGDIGVYVLHLERRESY-AYRADEPWYLASGVKIPVAIAVMRAVE -DGELSLDTRIALRETDFVDGAGGTNRHPAGALTVAYLLEQMVVFSDNTASDVLIRSV-GL -ERVNAVAADLIDAHMRITT-LGDVRRAYYATHLNSATLVDYGRMLATLAEGQALGDEGTR -YLLDLMARVQTGKQRIVAGLPRRAGFAHKTGTQYR-RTCDLGIATVPTGARVVIAACVRG -TG--TAAGERALRDIGAAVT--- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7MVS9_9BACT ----LRSRVEARIAQAPARVGLYYRDLTSGDSL-TVGSALRFHAASTMKVPVMIQLFRDRD -AGLLKLDDSITVTNTSIVDSSPYQYKGIGQRVSIRQLIELMETVSSNLATNLLIERV-GA -KRANATAHSLGADSLVVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIANGTAASPASCQ -EMLAILSRQQF-NEGIPAGLPAGTRVYHKTGWIEQVVYHDAALVEPSARSRYVLVVLTAG -IAKN-DDAYALVRDLSRLVFE-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium autoethanogenum DSM 10061 TaxID=1341692 RepID=U5RZ10_9CLOT ------EKILDVIDLKKLNCAFVIKNLKTGEKI-AYNENVVVPSASLIKIPIMMEILNQVK -EEKLSLKQRITVEDNVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM -DNVNNYIKDLEIKNTVLQRKMLDSKAR-KEGRENKTTAADMAKFFEIIYKGERAKECYSV -IMKNILTSQLD-NSVMRLNIPDDIRIAHKTGDLN-GISHDAGIVYLPNVD-YIFCGLTWD -AV-TNNFARETIGKISKVAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A352NTD3_CLOSP -------------------CAFEVKNLKTGEKI-SYNENTVVPSASLIKIPVMMKIIELVK -EGSLSLKQRITVTDEVKVPFSILTLMESGNSYTLKDIITLMIVQSDNTAANMLIDIA-GM -NDVNDYIKKLGLKNTVLQRKMMDSKAR-EEGRENKTTAADMVKFFEQIYKDAESGSPYGM -LMKNILTAQLD-NSVMRLYIPDSTIIAHKTGDLD-GISHDAGIVYLPGIN-YIFCALTWN -APN-NNLARDTIGKISKTVYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A354MR59_9FIRM --kDLASRLSAVMDAFPARTALYCVDLTTGAPIaAIRENTRVVSASTIKVPILCCALQDVM -DGKLSLDQHLAIAPADFCSDTEVFEPYRQDGASLWEMLYWMIVSSDNTATNTIISLL-GH -DHVNQYCRTIGLTQTSLQRKMLDFQ-AIAEGRNNYTSPADLYRVFSLLYHGEILNKPLRE -VAFDFLSRCRS-TDALQRYIPDAVTVLHKPGGLDH-LNHDAGIFLTEDR-PYYLGIFTWD -GPDGQPQQNRLIGQLSRMIYDA- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A2R7LG72_9CAUL -------------RAAPAVLGVGLLDGQTGQLL-GFNGDRPFPLQDLSRLAIVAAVLAEVD -AGKLSLSEPVIVRDIDLSPPSPVAEAWPGRTYTIGDLVDRTLSTADNTAADLLMKRIGGP -GAVSAWLELKDISGLHLDRREPEINAAYLTDGRDTVTPLAAVRFLDALRAGQLLSPASTG -KLLGLMALHRPGGDRLAAALPAGSILTHQTGNVRAAATSDIGIISLLDGRQFVVATFLGA -SSASDQVRSALITEVGRTIL--- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella buccae TaxID=28126 RepID=Q8KT58_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNGFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNDASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMFMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Tumebacillus sp. BK434 TaxID=2512169 RepID=A0A4R2R5C1_9BACL ---ALTPALQRMIEAARGTYGISIYHLESQSEF-TYQPDEWFYAASIIKVPIMAAVFDQAF -KGNLRFEEKIALRAEDMVTGSGLLQNLSPGLLSIYDYTMLMIIDSDNTATNILIDRI-GT -QAIQDAMAEWGLTGSGFYNKISVIPAKIEN--YNKITPRDMTHLLKLIADGKVVSWRACA -EMVKIMKQQKY-NEGLPSLLPTQWECAHKTGWVN-GTDHDMGLLYFPRN-TFAVSVFSKN -II-ERKDAHGLMGQIGRLLYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A399ZUW7_9CHLR ---ELRIQIEDIIAGVQADLGVSILHVESRATV-DITADTPVPLASVVKIPVLLEAFRQLG -EGRFQLDDRWPLEHAYKALGSGILTQFDDGLPTVLDLITLMIIVSDNTATDILMQRL-GV -QAIDDFMHRLGLTQTHVAHTLGEIFAYSLSADNNVGTPRELTRLLEMIYAAGVLDRGACD -QMLQILLKQQL-NDRLPRFLPAGTPIAHKTGTFS-GVRNDCGIIYVSEASHVVVTVLGTW -DH--------------------- ->[subseq from] serine hydrolase n=1 Tax=Agrobacterium sp. LAD9 TaxID=2055153 RepID=UPI0012906067 ------------------------------------------------------------- --------------------------------------------------------TIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADIVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=A0A415DVK0_9FIRM ----LKEQLIAYLNKEKVQGAFLIKDLSDGETF-CYNEYLKVPSASLIKMYILVEAFRRIK -GGLLTLDEEIAVQKEDLVDFSVL-QFLRPRIYSLEELLRLMVVYSDNTATNVLVDYF-SM -SSLNELMQQIGCKTSVIQRKMMDFAAA-EEGRQNYTSVIDMASLLERLYQGKLLGQPFDA -QMLDIMKGQAD-EEAMRRDLPDELIIARKSGELD-ALDHDIAIVYAEKRN-YIYVFFSWE --TGDNNRGRKVLAETSRLVFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Xylophilus sp. Leaf220 TaxID=1735686 RepID=A0A0Q4GP91_9BURK ---RLVHDLAQVSAGHSAGIGVYVRDLDTGVSA-RFQSSESWYLASTVKVPVAIAVLRGIE -RGQYKLDTTVTLEASDYVDGAGLTNRNPVGSLSIRYLIEQMIVHSDNTASDMLIGLV-GV -DALNALVAELVPQGFGRITRLAEVRRAYYASGLNSARLDAYGELLARLAQGQALGPASTD -YLLRVMERVATGTHRIKAGLPPGVVFAHKTGTQRR-RFCDAGIAYTPAAG-AATAAPTTP -PHAGHPHRAVV------------ ->[subseq from] class A beta-lactamase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0006220BD3 --nSVQQQLEALVKSSGGRLGVALINTADNSQI-LYRADERFAMCSTSKVMAAAAVLKQSE -SDKHLLNQRVEIKKSDLVNYNPIAEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGP -DKVTAFARSLGDETFRLDR----------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NIK7_9ACTN -------------------AGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. OK042 TaxID=1884381 RepID=A0A1I4CPX6_9BACL --eQLREKLTQLLDKAEGSWGVVVEDLDRGQRF-AHRPDEAFIAESVIKVPIMAAVYAAAA -QGAFQLDDRIPMRAEDQVGGSGILFALSPGLLTIREWVTLMIIQSDNTATNVLIDLV-GR -QRIEQTMIELGMEKSKYSRKLMIYPVG--ITENNMITPGDVSRMLGSIATGGFLSHHACE -EMVSIMKRQQV-LNGLPSLLPPDWEIACKSGWDS-GRQHDVGVFYSQGR-RFSIVALSQD -VQ--SESALRVLGQIGKEVYEY- ->[subseq from] Putative beta-lactamase n=2 Tax=Desulfovibrio piger TaxID=901 RepID=B6WTZ1_9DELT ---SLERDIHALMRDKKALAGVALL-TEDGLCA-GVHMDTPFPLLSVIKFPLAVAVLEKMQ -QEHTPLTTRIPVRAGQLHPHSPLRDKYGQRDLSLQELLHATVTFSDNNGCDILMDYVGGP -SVVEACARRLGADSVFIGHNEDWMHQNIYNQYANWGTPRSMARMLLGFFSSPDIPQAHKD -FMAGIMAKTPALPGKILEGLPQGMTAGHKTGSSDRTADNDLAFFRLPDGRYVALAVFLCN -SLESPETNLSLITDITRLSV--- ->[subseq from] Beta-lactamase n=1 Tax=Calothrix sp. NIES-3974 TaxID=2005462 RepID=A0A1Z4NG73_9CYAN ----LDTQIRQLMNRYSLSPGMFFVDLQTGDYL-DINGDRIFSAASTIKFPILVALFEEIE -AGRIRLDELLVERADLKVGGSGDLQYKPAGSFTVLETATKMMTISDNVATNMIIDRLGGK -NVLNKRFRHWGLQQTQINHLLVDEYG------TNKTSAKDLVKLAALVVNNQLINENSRT -HIYNMMGNCHN-QSLLPKGLGTGAKIYHKTGTLRF-VLGDAGIVKTASGKVYLAGIIVQR -PNHD-ESAIRFIREVSRLVYNYf ->[subseq from] Beta-lactamase n=1 Tax=Anditalea andensis TaxID=1048983 RepID=A0A074LF54_9BACT ----LRTEIQQAFSEVEGDFGLAFKYLGNDNHSlYINERENFHAASTMKTPVMIEVYKQAA -AGKFMLTDSILVHNESIIDGSPYSYHQIGNKTTIYDIVYPMITRSSNLATNILIDMV-GA -ENTTNTMRDLGAKDIQVLRGVEDQK-AYDAGKNNTTTAYDLLVIMEAIATQTAVDPHADQ -EMFKVLADQHF-RDLIPADLPEEITVAHKTGFIT-GVQHDSGIVRLPDGRQYVLVILSKN -LN-DSTQGKQVIAKVSRKIYDY- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI001362A828 ---TVEGTIQDAFGDISGDIAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Serine hydrolase n=2 Tax=Pseudorhodoferax sp. Leaf267 TaxID=1736316 RepID=A0A0Q4XSG0_9BURK ------PELARIDAEGGPRIGVYVRDLATGASA-SHHASEHWYLASTVKVPIAIAVLRGIA -RGDYDLETPITLRATDYVDGAGRTNSPVGTGLSIRFLMEQMIIHSDNTASDMLIGLV-GL -PQVNAVVQAIAPDAFGPITTLAEVRRAYYASGLNAGRLDAYGELLAQLVDGKLLAPEQTR -YLMGLMERVATGTQRIQAGLPPGARFAHKTGTQR-ARFCDAGIVRTATGERGVLVVACTQ -GDLSLVRAERALRQVGTALC--- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8CLK0_9BACT --qRLEASIQRTTRSVNATWGIYLKSLETGEEI-ALDADRQMETMSTIKIPLMVEVFAQIT -RGRFSLTDKYTFAPADSQPGTGTIQRLDPGAMTVKDLITMMIIVSDNTATEVLYRMVGGV -AAVNARMDALGLKQTRAMRWFPLLRARDGKSPFGLSTPREMGRLLEMMERGTLVDKVSSD -LMLRIMRGQLY-RTRIPRYVT-GYTIPHKTGDFLPYVGDDVGMLEAPDRT-IIISIFTGN -HFGSGEALENAIGLVAKDVADYf ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI0009E22F29 ---DLERRLQAIDAGLGGDIGVYVLHLERRESY-AYRADEPWYLASGVKIPVAIAVMRAVE -DGELSLDTRIALRETDFVDGAGGTNRHPAGALTVAYLLEQMVVFSDNTASDVLIRSV-GL -ERVNAVAADLIDAHMRITT-LGDVRRAYYATHLNSATLVDYGRMLATLAEGQALGDEGTR -YLLDLMARVQTGKQRIVAGLPRRAGFAHKTGTQYR-RTCDLGIATVPTGARVVIAACVRG -TG--TAAGERALRDIGAAVT--- ->[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0675_bin_29 TaxID=2605266 RepID=A0A6B1G2L9_9CHLR ---SLESDIRDISANSGAEMAVSALHLETGQHI-DVDAERVYPLCSVLKIPVLVEAFRQIE -DGLFTLDDRWQLTTAEKNLPSGILVFFDDGLPTVKDLLTLMIIISDNTATDMVMHRL-GQ -GSVTRTMHDLGLTDIHVPLTIRELFDYSLGPDNDTGTPAALTELLARIWRGEAVNRAACD -AMLEILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GIRNDSGIIYAGDNSHVAVTVFSRW -DDEA------------------- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7MU59_9BACT -----RERLAARVAQAPATVGLYYRSLTRPDSL-VLEANVRFHAASTMKLPVMIQVFRDAD -AGLLRLDDSLTVHVVSLVDGSPFEYGRVARPASVRDLLELMITRSSNLATNILIERI-GA -ARAQASARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQNRAASPASCR -EMLRILEAQEF-NEGIPVGLPPGTRVAHKTGWIGEVVYHDAAIVYPPSGGSYLLVVLTGG -IKQD-SVAHNLVADVSRLVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520G9T1_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEALRQALGVPRTSLKATIDEAYARYYEKQLNAATLEGYGAMLEKLVQGKLLKPASME -RLFTAMKIRIFTNYRLQAGLPRSASFIHKTGTQYR-RACHAGVINPQDGAKAIVVATCAA -DIDEQKDAGRVFEQVGRAITR-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=UPI0011B696DD -------------------AGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium AC-409-J13_OGT_754m TaxID=2587834 RepID=A0A5N8YHP9_9CHLR ---------DEAIARVPGLVGFFAEDLTTGEHF-SHNADKTFFTASTFKVPLLVGLFTQVE -SGNIGLSERFKLKEDMKVAGSGVLKEMDPGILTIHDLAMLMIIVSDNTATDIIYDLV-GK -DNLREILAPLGLTNTRIPMTCRELLCGFNEETSDVSSPRDMANLLKFIERREVVSTKACE -QMLNILKRQQL-REMLPKKLPKEVHVAHKTGGYFR-VQCDVGIVYTSKS-SYSVAIMAKK -IT-DMRGIQDAVADLSEAIYFSf ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. NEAU-YG30 TaxID=2249762 RepID=UPI000DE1E16A -----------VFRAAGVTGWLHAADLDTGREV-GHGSDEPVPTASVFKVPLMVELCRQAD -AGLLDPAARVTVRAADRVFPTGVSAMLDDVTMSLRDLAYLMIAVSDNTAADVLSARV-GL -DAVNAMLSRFGLEGTRVRHTTAALFEVLDPRRANRSTPRETARLFGLIWRDEAASPGSCA -WMRAVLNKQVW-PHRLASGFPDDVDVSGKTGTLPT-LRNEAGVVEYPDGGRYAVAVFTRS -SSVNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=2 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=A0A386U3T5_9MYCO -----ERQVERRILAAPADVAVFFRLLGGESEW-SYQPDDTFHAASTMKVPVMIELFHQAH -QGQLTLDDPLLIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLSAIAEGKVVDSDASR -QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYGP--QPFVLVILVRG -MAN-SKDSSALMADITRAFYR-- ->[subseq from] Beta-lactamase n=1 Tax=Chloroflexi bacterium OLB14 TaxID=1617415 RepID=A0A136KVD6_9CHLR -------QIENFISQFDKTISVSVYDLETNQEI-NINADVLMHPASVMKVPVMMEVFRLAQ -AGTLSLDDEIELYNSSIVDNSQYQYTKIGEKETIRELNRLMIIRSSNLATNVLMDKV-GT -KAINDFIQALGIKDMTVLRLIEDKL-AYGLGINNAFSARATTYMMRLIAEGKVVSKQASD -EMIQVMLGQEF-NESIPALLPKDVKVAHKTGWNED-LFHDSGIVFPPNRKPYAITLFTDG -FPNDNSQAHKCMAEVSKLVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A2W5L635_VARPD --eRLTNALERIDAAPGPRIGVYVRALASGESA-SFRAGQSWYLASTVKVPVAIAVLRGIA -RGDYQLDTPVTLRADDYVDGAGATNRHAVGALPIRFLLEQMVIHSDNTASDMLIGLV-GL -EQVNAVTAEVAPAGFGPITRLAEVRRAYYATGLNAGRLDAYGELLVQLADGRLLPPAQTR -YLLGLMERVVTGSQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAAGTRVVV-VACTR -GALSLARAERALREVGAALC--- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sporothermodurans TaxID=46224 RepID=A0A2T6EHN3_9BACI ---SLRKQIDGIIEQSLGIVSIVVE-INEETII-SKNSKREMSSASLIKIPIIMAAFQQAE -LGKIDLEEKIEVKPEHKVGGSGVIQYLTEGTLSVKDLLTLMIIVSDNTATNMMIDLV-GQ -ETINYFNKQIGCNHTRLERRLMDYVAR-DMGLDNVTSASDMVIFLKEIVENQFLTSKSTY -EILNILSGQQF-QDKLPAMMDDHVFVANKTGEIP-GVEHDVAIIRHNDD-QVFMAVLIDQ -LE-NQYEGKQIIARTGKAVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus borstelensis AK1 TaxID=1300222 RepID=M8DDI2_9BACL --kSLQEKLETIIAAAGGQWGVVVEEINGSFYW-EHNTTQTFAAESIIKVPVMAAVFDAAS -KGKVRLDETVLMKQTDQVAGSGVMQHLTPDTYPVYDLITLMIIQSDNTATNMLIDLI-GE -DQVRLTMAELGMHDSCYSRKLMLYPAD--SPPNNMITAGDIARMLKRLATGTFLGEHACR -QMIGIMKKQQV-RNALPARLPAVWEMANKTGWDT-GRQHDVGILFAGGK-AYSLTALSEN -APPD--ASLQAMAAIGYEVY--- ->[subseq from] Beta-lactamase AST-1 n=1 Tax=bacterium HR28 TaxID=2035423 RepID=A0A2H5Z476_9BACT ------RAIRLALEQVPARVSLSFCDLDRQWKI-AHDADHPVTAASTIKLLVLVTLYRAFA -RGDLDPNESIALTPDAVVPGSGVLRWLRHRPLTLRDLAVLMVIVSDNTASNLLIERL-GW -SAFAALATELGLAQTALRRRFAGR-AALPGEEENVTSARDLAQLLASLEKGKIVPEPWLE -DLRTILTAQQF-RDIIPARLPADVRVGNKTGSLP-GFLHDAALLWAPHGR--ATLVLLAR -DVHDAELTRRALADLARAVYDEw ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas sp. Mitacek01 TaxID=1732019 RepID=UPI0006DB8C12 ------------------------------------------------------------- ----------------------------------------------DNMAIVRLRNAEAGE -ARLQALARELGVARTDLDATLEGVFDAYYRGDRNTATLPAFATLLDRLAAGELLSPDSTR -LMLDHMRGISTGNRRISAGLPPGTDFAQKTGTQLR-RACNVGVIDPEARDGATLVLACAE -DFDDIVDAETAFQGLGRAL---- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=UPI0012B9C903 -------QLRQVVDAATANAGVTVRDLSGQQQV-SVNGTLRPKAASVIKLWILVELLRRVD -CGQVSLDQGVLVTAADVVGGTGQLQEQIPQVASLHKLAEYMIEYSDNTAANVLIDQLGRF -APVNALIDSMNQRETILARKMLDTEAA-ARGEENYTSPDDVVSLLGAVWDARILTRASRD -LMIGFMREQTL-NSKIPAALPPGTPVAHKTGDLPD-ASHDVGYYLVPGA-ETAVAFLTAG -PY---DSGSETVRRLARTVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Marinamargulisbacteria bacterium SCGC AG-414-C22 TaxID=2184344 RepID=A0A328RDT2_9BACT ----LQTELDSVIKHQPYTIHFGAYHVESGDYV-YLNPDKRFPMASTVKVLFALTALDLVD -QGMLSLDQTLTLTKKDIRPYSVLSLFARDPQMTLENAVEAMLIYSDNSATDAVFHACGGK -KAVNRFLKKHQLQSLTVSGSILAMLAQFFKSPKDTSTVRAWTTLFTKLLNGDLLSDQSTS -YVLTVMNQSHWGKKRIKGFLP-HVQVSHKTGSFSK-CTNDVGLITLPNKGHLIIAASVID -REPEEAKRDHVIALLTKTVYDFw ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. SCSIO 07484 TaxID=2496837 RepID=UPI000F82D386 ---RIGETVASLVEAAGGTWGIVLERLGTGESW-CLNGDRPFYAASLIKVPIMVAVFADVE -EKKYALADRLPVRQEDMVGGAGVLQHLTPGEYPIHDLVTLMIIQSDNTATNILIDHV-GR -ERIRAIMKKAGMQNSRFYNKLMVIPAELEG--TNQVTAADMAELFRRLAGGRIISYDSCL -RMIAILKRQQI-RQSLPLYLPEPWELAHKTGSVRS-IEHDVGILYVGR-DAFLLSILSQD -VPS--QLARDTIGRICLAVYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Elusimicrobia bacterium HGW-Elusimicrobia-1 TaxID=2013763 RepID=A0A2N2F0G8_9BACT -------EFERISAALGARVSFYYKDLSDNFEY-YHRPDDPYPSASLVKLPVMACVMAAVE -ENRLPPDLSIVYRSRHRVGGSGSLRYRYGRRVGLDELTYRMIVESDNVATNMICDTL-GL -GYINEKMLGWGMDVTDMKRWVLDLRRR-NQGVENYTTSREMGMLLEKIYRGQLVSRRASM -QMLEIMKNQHY-RNRIPRYLPPGVVVANKTGLMRN-VVHDAGIIYSTDGD-YVLCVLTRD -IP--SKTAARLIGEISHLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium aurantibutyricum TaxID=1551 RepID=UPI00098C3770 ---ALDNAIKNILALRCEDISLVFLDLNNTSNYiYINENKIFPSASTIKVLILAEALNEVL -NGKLSLDAPIEVKTSDKVPYSILTS-LTNNKYPLIDLLTLMIISSDNTASNILIDLL-TM -DSINNYGQSIGLKNTSLKRKMMDSKA-VQRGMDNLTSALDMLTLFKKIYNHELLNPKMCD -LILKILGNNTD-KEVLLRYLDADIRCAHKTGDLSN-LNHDIGVFKTKTS-EYILGVFVRN -ADFN-YVAKDLIGKVSKIVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561WCH0_9ACTN -------QLRQVVDAATANAGVTVRDLSGQQQV-SVNGTLRPKAASVIKLWILVELLRRVD -CGQVSLDQGVLVTAADVVGGTGQLQEQIPQVASLHKLAEYMIEYSDNTAANVLIDQLGRF -APVNALIDSMNQRETILARKMLDTEAA-ARGEENYTSPDDVVSLLGAVWDARILTRASRD -LMIGFMREQTL-NSKIPAALPPGTPVAHKTGDLPD-ASHDVGYYLVPGA-ETAVAFLTAG -PY---DSGSETVRRLARTVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7SEI9_9BACT -----------IARAPATAVGLYYHNLTRPDSI-LIGANLRLHAASTMKVPVMIQIFRDAD -AGLLRLDDSLPVHATSLLDGSPFDYLRLGGKASVRELLELMITRSSNLATNLLIERV-GA -ERAQGTARSLGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQGRAARPASCT -EMLAILGRQEF-NEGIPAGLPSGTRVAHKTGWIGEVVYHDAAIVHPPRGGSYVLVVLTGG -IKED-SVAHSLVADLSRMVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537IPD5_9BACT ----VPEEVQRLAEGFSGVLGVWSHSFTSGETL-EWNAGEVFPAASAIKLPILYEVYRQAG -EGRFRLADTRSVQAADVVPGSGVLKDLTPGVLSIRDLATLMIVVSDNTAANLLIDLV-GI -DAVNRSMRALGLGASVLEHKF---FHAPPGAPPSRSTPADLGSLMMQIAGRALLTPAACE -EMLVILRRQHYTDHITRAGVEPVITVASKSGSIR-GTRNDVALVESPNCR-YVIAMMSRD -CKDRDNEAAVLLAEVSALVYQHf ->[subseq from] Uncharacterized protein n=1 Tax=Anaerofilum sp. An201 TaxID=1965588 RepID=A0A1Y4HEK8_9FIRM ----LYGRICSILEGIPGRLSVAVRWLDSGETL-LLHETLPFVAASVIKLPVMIAAFAARE -AGTLDFSAPVPLRAEDKLPSCGVLKAMHDGLPTVADLCHLMITVSDNTAANRMIRLV-GI -DAVNGCMAQYGARDSRLRRLLFDADAS-AKGIENTVTASDMLLLLQKLYAGEIVSPEASA -EMLDILADQRL-NGKMPFWLPPGTRCAHKTGEDD-GITHDVGIVYAA--RPFAGCFLSQH -TD--PPRFIRAIQDITRLLYE-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8K2T2_9ACTN --------FAELFRVAGVTGWLFAADLDSGREV-GHDPDEWLPMASMFKVALMVELCRQAD -AGLLDLTGRVTVTAADRAAPTGLSAMHDDVTMSLRDLAYLMIAVSDNTAADALLSRV-GM -DAVNAMLEGFGFEATRVLMTAGETNGALDPARTNRSTPRELARLFGLIWHDEAASPESCA -WMRTVLNLQVW-PHRLAAGFPDDVAVSGKTGTLPT-MRGEAGVVEYPDGGRYAVAVITRA -FSLNHPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium MedPE-SWsnd-G1 TaxID=1860094 RepID=A0A1J5MA93_9BACT --qDFKNQIQNDLKNIKGNTALVLFDLNQNKTLlNINSKAEFHAASTMKVPVMIEVFKQAR -EGKFSIKDSILVKNESIVDGSAYQYKMVDKKVTIEKLVYDMITVSSNLATNILIDMV-DA -KKVTETMRSLGADKIEVLRGVEDQK-AYDKGLSNSTTANDLVQIFKGIASNAAGSESECN -NMLSILKDQKY-NDLIPKYYPKNVTVAHKTGSIT-GVHHDAGIIYLPNGNSYVLVILSKN -LE-DFDRGTDALAKISKKILD-- ->[subseq from] serine hydrolase n=1 Tax=Fictibacillus gelatini TaxID=225985 RepID=UPI000427F90F -------HLQEVATGICGKMSIVLEI--ENLQI-SINGDDPFPSASLIKIPIMMEAFRQAQ -IGMLDLDETYRVPSEAPVGGMGVIQHRPEIELSIHDLITLMIIVSDNTATNLLIDLV-GM -EAVNKLSSDLGCNQTLLARKMMDVTAQ-KNGKDNWTSAYDIVKFLKEIDQGKLLTSKQRT -NALKTLRQQQF-HSKLPALISEETYVAHKTGELP-GTEHDAGIIQANGK-RAYIAVLTTD -LDNN-ITGQKAIAQIGKLVFDH- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8J4H7_9BACT ------------------------------------------------------------- -------EQLIQVTTNDFVTHSPIRDAHPLGALSVSNLLRQMVSESDGTACDVLLRLLNGP -PSVDHYLRELGLTNVVVATSEKEMGQDELAQYRNWATPEGLTGLLRILHEGRGLSVPGRE -MLLRFLTETSTGPRRIRGLLPTGTRVAHKTGSSRTRATNDAGIVTLPDGRHMAIVVFVSD -SAADEVTRDAVIAKISRAAWDYw ->[subseq from] serine hydrolase n=1 Tax=Deinococcus pimensis TaxID=309888 RepID=UPI0012FC2D55 -------------AGHPGHVSVVVRDLTSGEVLrEHDPDRVYPAASTIKIALLVAALRLVD -AGAAHLDERPVMDAGDRVGGDGVLKELVAGLPTLRDLLTLMIVVSDNTATNMVIDRV-GV -DTVNAFLREAGLSGTELLGKLPERQSAQRAGERNRTTARDLAELLLRLARGELLSRSSTE -VALDILSRQQH-QNILTRHLPRDWRVASKHGELR-GVHHDVGVVWSP--RPVVLAILSEG -GLDP------------------- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus sporothermodurans TaxID=46224 RepID=A0A2T6EVD7_9BACI ---SLRKQIDGIIEQTLGIVSIVVE-INEETII-SKNSKREMSSASLIKIPIIMAAFQQAE -LGKIDLEEKIEVKPEHKVGGSGVIQYLTEGTLSVKDLLTLMIIVSDNTATNMMIDLV-GQ -ETINYFNKQIGCNHTRLERRLMDYVAR-DMGLDNVTSASDMVIFLKEIVENQFLTSKSTY -EILNILSGQQF-QDKLPAMMDDHVFVANKTGEIP-GVEHDVAIIRHNDD-QVFMAVLIDQ -LE-NQYEGKQIIARTGKAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=UPI0002D1ABA6 ---SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE -EGTLSTDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE -KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETSLWLY--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI00142D4197 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPDTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3C2DN38_PSESP ----FLAHIARVDDQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE -EGALSLDTGVPLLASDYVDGAGATNGFVPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL -ERVNAVTRELVPQGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR -YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR -EAASTAKAERALRGTGEAVT--- ->[subseq from] hypothetical protein n=1 Tax=Sulfobacillus sp. hq2 TaxID=2039167 RepID=UPI001304CC79 --------LREWIGTLPGIYGVFAKNLDTGKVF-TFNDTKVFPSASTIKVPILIELYRRVE -EEHLSLDHLLVMRREDQVGGSGVLKDLSPNTYSLRDLATLMITVSDNTATNLLIDFL-TI -EAVNITLRRLGVTHTELVRRLQRVPA-EPLDTVNHTTAQDMGLLMEKLATGTAISLAASE -QMVSLLKRCQG-PISITKLTAESIVIAHKTGSLAQ-ASHDVGIVYSPHLR-YVAALLSQG ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561W9F2_9ACTN -------------------SGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPEDIVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BP16_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFKGFLAAAVLARSQ -QQAGLLDTPIRYGKNALVPWSPISEKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWE--------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Butyricimonas synergistica TaxID=544644 RepID=UPI0003728B1D ----LTDTISKIVSGYPGEIGVAVI-INNMDTV-TVNNKSIYPMMSVFKLHQAIAVCNDFD -RKGLSLDSLMCIKRDELDPWSPMMKEHSEPVLTVKDLLRYTLIQSDNNASNIMFKELVSV -ARTDSFIATIPRTSFRIAYTEGEMSVDHDKAYSNYTSPLGAAMLMNRLFTDSLVSREKQC -FMMNTLEECITGKDRIVAPLKEGITIAHKTGSGYNGAHNDVAYIRLPNNVCYSLAVFVKD -FKGNEAQASKAVACVSAIVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salinarum TaxID=447422 RepID=A0A2N0TQX1_9FLAO --eKLQHQIDSIFKRTQGDFAIAFKDLSTENHSiFINHHEDFHAASTMKTPVMIEVFKQAS -EEKFSLQDSLLIKNESIVDGSSYSYVQIGQKRSIEDLVTDMIIYSSNLATNIVIELV-DA -KNVNKTMRNLGALNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALANGNVVNPEADK -KMLEILRQQKH-NDLIPHLLPEDLNIANKTGWIT-GVHHDSALIELPDGTKYILVLLSKN -MK-DMDAGTKMLTEVSKMIYDH- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas songnenensis TaxID=1176259 RepID=UPI000EFDA22E ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGRLFEQVGQAIS--- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645AQ81_9ZZZZ ----LKDDILKCFDRMEAKVSIVLKDLLKEEVMlELDAARVVPSASTIKILIMIEALKQVM -EGRISLDEMVFVKPYERVDFSIISE--LGAAYSIRDLITLMIIISDNTATNVLIDIL-GY -DNINDQAEKMQLKGTVLQRKMMDFEAA-RQGRQNLTTARDMAYMMEALYKESILDRNMCD -LALNILKRQKH-KDLLTRYIAEDIVVAHKSGDLEN-LNHDIGIFYLTDT-VYLLGVFVTE -AE-SNVSAKHIIGKVSEAAYKYf ->[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas fulva TaxID=47880 RepID=A0A0D0KK47_9PSED ----LLERLQTLAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAIAVLRGVE -RGDWNLDSRLTLAADDFVDGAGSTNQYGPGELSVGFLLEQMIIYSDNTATDRLIRLA-GL -DAVNALVGELVSEGFEPITTLGDVRRNYYRSNLNAARLSAYGELLERLADGQALGAEQTR -YLLGVMGRVKTGSKRIVAGLPDDARFAHKTGTQRE-RICDSGLIETPARQPVLIVACVQG -E-PSLAKAERSLRQVGEALT--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8PL81_9BACT ------------------------------------------------------------- ------------VTKKDFVRNSPIRDEYPNGTLTVSELLRYAISKSDGTASDVLMRVAGGA -DAVQSYLGELKINEMVIANTEKEIGQDWETQYRNWSSPEAAVALLRALHERRGLSESGQM -LLLKFMIESTPGPKRLKGLLPAGTIIAHKTGTSGTAATNDIGIITLPNGKHLAIAVFVAD -SAADEASREGVIAKIARAVWDTw ->[subseq from] Serine hydrolase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A3D0RNT1_9CHLR -------QLEKFIAQFNKTISISVSDLETNQEI-NINADVLMHPASTMKVPVMMEVFRQTQ -VGNFSLDDQIEIYNSSIVDGSDFDYSRIGEKETIRELNRLMIVWSSNLATNILMDKV-GT -KPIDDFIKELGIKNVNVMRLIEDKQ-AYRLNINNTFSARGTTHMMRLIAEGKVISQEASD -EMIKVMLGQEF-NESIPALLPKDVKVAHKTGWTGE-FFHDTGIVFPSNRKPYAITLFTNG -FPDDESQAHNCMAEISKLVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas songnenensis TaxID=1176259 RepID=A0A482UH65_9PSED ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGRLFEQVGQAIS--- ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2WQE7_9FIRM -------ALQELIDSLPGRYAVFAKNLVNNKTF-DYHANETFPSASVIKIPILMELYRRVE -ESHLSLDHLLLMGKEDQVGGSGVLKDLTPATYSLRDLATLMITVSDNTATNLLIDYL-GV -DNINATIRHLGAQNTELIRKLQRVPAE-QHSRVNHTCAYDMALLMEKLATGTATSLAVSE -EMVSLLSRCQGPVSIAKAPADNDVLIAHKTGSLSE-ACHDVGIVYSPQIN-YIAAILSEG -A---------------------- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2U8SYZ3_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGRLFKQVGQAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium MT.SAG.2 TaxID=2552983 RepID=A0A4Y8I9N8_9BACT -------------APSGAEVSVAYENLQTDIKM-FINAKKQMHAASTYKTALMVEVYKQAA -EGKISLTDSIDVINSSIVDNSEYAYELIGKRASYYDLTYQMITVSSNLATNLLINEV-GA -KNIMKTLKSIGIKEMQVLRGVEDLK-AYELGLNNTTNAEDILRLMIAIAKDEVVSPSACA -EMRKILLAQVH-NSKIPAKLPKEVKVAHKTGSITK-IDHDVAIIYPPKGPVYALVVLTRG -IK-EHKDAEELIADISKIVYD-- ->[subseq from] Uncharacterized protein n=2 Tax=Cyanobacteria/Melainabacteria group TaxID=1798711 RepID=A0A349HYE1_9CYAN ----LQSELTNLMAQYTIQPSVYVWDYETGNYV-DINASKVYATASIIKIPVLIDLFKSIE -AGQVSLEETMPLTEYFRTEGSGSLQFKAAMSYTIDKLAELMITESDNSATNMLMTRVGSM -VDVNQAIRDWGLKNTEVQTWLPDYAGT------NHTTAREMGRMLYNIDEDKFLTQESRA -KILNYMGHVHN-NRLIHAGLGAGAVFLHKTGDIGT-MLGDAGIVIAPNGKKYIVVILANR -PH-NAIEGKDFIVHASELIYNY- ->[subseq from] Beta-lactamase n=1 Tax=Brachyspira sp. CAG:484 TaxID=1262759 RepID=R5HJN5_9SPIR --------IKNLMTAYSIHPSVYVWDYDTGHYA-DINASELFSAASIIKIPVLLQLFRSVD -LNQVSLYDEMTLTEYYRSEGSGGLQFKAANSYSLDTLARVMITDSDNTATNMIMSKIGSM -TDVNQGIRDWGLKQTHVKTWLPDLQGT------NHTTARDLGVMLYNIENPKFLSMSSRE -RIFDYMGHVKN-NRLIQAGLGPGASFLHKTGDIGK-MLGDAGIVYTPNGKKYIVVILANR -PYN-SPAGKDFIVRASEIIYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus sp. TaxID=33949 RepID=A0A357A2I6_9FIRM -------ALQELIDSLPGRYAVFAKNLVNNKTF-DYHANETFPSASVIKIPILMELYRRVE -ESHLSLDHLLLMGKEDQVGGSGVLKDLTPATYSLRDLATLMITVSDNTATNLLIDYL-GV -DNINATIRHLGAQNTELIRKLQRVPAE-QHSRVNHTCAYDMALLMEKLATGTATSLAVSE -EMVSLLSRCQGPVSIAKAPADNDVLIAHKTGSLSE-ACHDVGIVYSPQIN-YIAAILSEG -A---------------------- ->[subseq from] serine hydrolase n=1 Tax=Gelidibacter mesophilus TaxID=169050 RepID=UPI000415AE3B --eDLEKTIQNQIDSIEGTVAVAFYSLSEPKDSlLINADEKFHAASTMKVPVMIELFKQAS -EGKLDLKDSILLKNESIVDGSLYSYSQIGTKVALWDLMHSMITVSSNLATNVLIELV-DA -KKVTASMRRLGAKDIEVLRGVEDQK-AYDKGLSNSTTAKDLMVIMEAIANKTAGNQKDCD -AMIAILKDQQH-NDIIPLYLPKEIEVAHKTGSIT-GVHHDAAIVYLPDGRAYILVLLSKN -LK-DFDQGTDQLANISKTIYDY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI00124AF7A9 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPDTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DD5B7F2 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPDTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodothermaeota bacterium MED-G16 TaxID=1986238 RepID=A0A2A5XJ05_9BACT --pSLQNNIEKIIKSEKGKFAIAFKNLEDGQVI-LINEMEEFHAASTMKTPVMIEAFKKSF -ENKISLDDTILVKNESIVDGSLFKYERIGGHLSLRELIYEMITISSNFATNLVIDYI-GH -EDINKTMRDLGAKDINVLRGVEDIK-AYNKGLNNTTTALDLLKIYENLALGRVINTKLSQ -KMVDILKDQKY-DDIIPKYLPKEIEIAHKDGWVS-GTRHDSGIVFINDEKKYVLVLLSKN -LE-DEIKGADILAKVSLEIYN-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:813 TaxID=1262843 RepID=R7MIN3_9CLOT ----LQSELTNLMAQYTIQPSVYVWDYETGNYV-DINASKVYATASIIKIPVLIDLFKSIE -AGQVSLEETMPLTEYFRTEGSGSLQFKAAMSYTIDKLAELMITESDNSATNMLMTRIGSM -VDVNQAIRDWGLKNTEVQTWLPDYAGT------NHTTAREMGRMLYNIDEDKFLTQESRA -KILNYMGHVHN-NRLIHAGLGAGAVFLHKTGDIGT-MLGDAGIVIAPNGKKYIVVILANR -PH-NAIEGKDFIVHASELIYNY- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI00132F7441 ----VEGTIKDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFIMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKELIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Cephalosporinase n=1 Tax=Bacteroides sp. CAG:927 TaxID=1262753 RepID=R5BAE2_9BACE ---ALQSRLQEYISGKNARIGVAVIY--DQDTV-SVNGYDEFPMMSVFKFPLALAVAQWAE -TNGVVLSDSISFGPDALRRYSPMLDKYGPSLLSIQELLKWSLMESDNNAADIILHLIGGP -EAATNLMKQAGCEAITIGASENDLHSRPDLILLNKATPIAMAALFHRFNTEIRHRSSSFA -EIATMLEQCRTGADRLAVLLPAKAVIGHKTGTGFTTALNDCGYVNLPDGRHYSIAVFIAD -SPYSTQATAKIIADISSIVL--- ->[subseq from] serine hydrolase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFBFB84 ------ESLNAYLQKLTVRVSLAVESLSDSTVGyFHQADEAVPSASVIKIPILIEAMEWVK -AGRINPDENHILLDSEKTGGSGILATYPHRTVSYRDVMTLMMTHSDNTATNLLIAEI-GM -EAVNARMRQLGLTQSRLNRVMMDTLAA-RQGRENRVSCREMNLLLKKIYRRQVATPALCD -EMLDILKRNED-TLTIRRFLPRSTVIAHKTGGLAY-VRGDAGIVFAP--RPFLFTAFVQG -TNT--GDAERIIGELAALCFKQf ->[subseq from] serine hydrolase n=1 Tax=Bacillus dielmoensis TaxID=1347369 RepID=UPI0005A6580E ----LEVKIAEELIEFKGRIGLAIEI--GNVRL-DFNSQDVFPSASVIKVPILIEGLRQCD -AGLINLDELIRIEN--RAGGSGVLESLSSEALTLLDLLTLMITVSDNTATNMLIDRL-GI -ESINRTITKIGMTGTVLNRKMMDFEAK-ERGLDNKTSAADMVCCLKAMNEGSILSETSRS -LALKIMHAQQF-QDKLPAMMDDKIYVANKTGSLPK-VENDCAIMAYNDQT-AYVAILTDE -LDEP-YTARQVISRIGKYIYDY- ->[subseq from] serine hydrolase n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=UPI0007EFFE7C -----ERQVERRILAAPADVAVFFRLLGGEAEW-SYQPDVTFHAASTMKVPVMIELFHQTH -QGQLTLDDPLPIHNESLVDGSAFYYSSEGQTRTLRQLCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR -QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYG--SQPFVLVILVRG -MA-DSKDSSALMADITRAFYR-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=A0A3L7BSG0_9ACTN -------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---ETGDETVRRMARTVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0AJK3_9CHLR --------------GTGGIVGMCVVA-PNGERW-SHNGDRQFGAASTVKIPLMVEIFRGID -RGERTLADPYVLRDEDRAAGSGVMLHMSAGDLTLWDLLYLTISISDNTATNLLIRMA-GM -DAVNATMRELGMPNSVLAREMKGR-PAIEGEGENWATANDYANVMLSILNGTAASADSCA -KMLDLLSKQQN-ARRIARYLPSDIRWGSKTGSVT-GVTNDVGFVTSSAGT-VVIAVFCEN -FP-DQHVGEYVIGALARAAF--- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium xiamenense TaxID=1297121 RepID=UPI0012B7E973 ---ALEDDIRSLMQATEGDFALAFRILDSGRQL-LINETEVFHAASTMKTPVMIELFKQAA -AGEFSLQDSILIVNESIVDGSTFRYERIGEKASLYELMYQMIIKSSNLATNILIDRV-GA -KNVTQTMRGLGAEDIQVLRGVEDLKA-FDAGLSNSTTALDMLQIMEAIARGKV---EGSR -EMVKILSDQYF-KDLIPNLLPADVKIAHKTGSIT-GVQHDTAILELPNGTRYVLVILSKN -LT-DVPAGKEAIARMSRLIYDY- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division KSB1 bacterium 4572_119 TaxID=1971636 RepID=A0A1W9SFP6_9BACT ----FETEIRRLEKYTGGRIGVMAKNLGSGEIV-SYRADEKFPTASVIKVPVMVEYFYQVK -EGKLNPTQKIVLADSNKWGGSGLFQYFQGTTQQLIDAVLMMITISDNTATNMVIDVLGKL -EAVNERMKKLGLKNTRLLNKLMSWETDSPESIRGVSTPADMVNLLEQMATFQLVDSTSSK -GMISILEKQEY-NTIIPRLLPPGLRVAHKSGSVT-GVRNDVGLIHSSKA-NIALAIFIEQ -SLKSGPENEAAAAKISRLVWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A2E1AJT3_9CHLR ---TLKDDIQAVLTQANIDAGVAVWHIESGEQT-DVNGDVPYPMASTFKIPILATVFTQIK -EGKLSLETRYKLTTEVKSPGSGILPYFQEGLPTLLDMLTLMIIISDNTATDMIVDILGGP -DVVESYMHQLGLTNIYFKMNCKDLIAFSLMPDNDIATANDMNKLLHMIYTGELFDGELRE -TALGILFKQQF-NVRMTRFFPPSVKVAHKTGTIG-GIRNDSGIIYINDDTHVILTLFVEW ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Falsibacillus sp. GY 10110 TaxID=2478915 RepID=A0A3L7JVM8_9BACI --nDLEREIMGIEAGCAGRIGLFISA-DEGQIM--TNEGESFPSASLIKLPIILEAFRQAD -ARKLDLNERIMVHPEEKVGGAGVLPALSDNIFNIIDLMTLMIIVSDNTATNLVIDKI-GM -KSINQLISCLDLKETLLSRKMMDFD-AIHQGRNNYTSPRDIVTLLKEIHHGEMLNEKSRQ -QIIGIMRQQQF-TDKLPALVEDKIRIANKTGELD-GVDHDCAIFEYGGK-TVFAAVLIDG -LV-DKVSGKYTMNQIGCAITDY- ->[subseq from] Putative Beta-lactamase n=1 Tax=mine drainage metagenome TaxID=410659 RepID=E6Q6H2_9ZZZZ ----LRDSLRSLARSSDANVGIAVEDLATGAVT-GYNLNRSMPAASTIKIPVMVEVFRQMA -RGRFTLTHVMHLREVDRDYGSGDLAYPLGTPVTVKRLLSEMIDVSDNTAANMLIRLV-GR -QRINAAMQAYGCHHTYLRTAIRTNVSSV--ETNLRTTPLDMLTLLVRMARGKLVDTWSSH -AMLEILAHQEI-DTLLPEPLPDGTTIAHKTGSLHD-VMADVGIVYEPGA-PFAIAAMTSG -LP-DPQLGRDIVRQAS------- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00128F231F ------------------------------------------------------------- ---------KVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQ----------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=A0A328NH74_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas stutzeri NF13 TaxID=1212548 RepID=M2VGZ3_PSEST ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEGAWYLASTVKVPIAIAVMRRIE -QGDFTLDSPVTLLASDYVDGAGPTNSHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -EQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGIALGPASTE -YLLSVMRRVETGVRRIKAGLPSGTGFAHKTGSQR-ARICDAGLVDQPGAQRLIIVACVRG -VA-STAQAERALHGTGEAVA--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7B6A6B ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARKLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Nodosilinea nodulosa TaxID=416001 RepID=UPI00031A7510 ------------------------------------GGNQVFPAASTIKLTILIAFYQDLD -AGKVSLNDTLVLRRDLLTGGSGAMQYEPIGSYSAKEVLKRMITISDNTATNLIIDHLGGI -DCLNARFRSWGLQHTVMHNLLADLRGT------NTTSAEDMVSLLAQVVEENLLSSQSQD -QVLNLLRHTTI-RSLLPAGLGPGANIADKTGDIGF-LIGDAGLIIMPTGKQYLAGIFVTC -PYND-VRGRNFIQEVSRTTYTY- ->[subseq from] serine hydrolase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI0005533C5F --qTMTAQFQPIADRVPGGLGVAVEDLGTGQVI-SFNGDRRFPLQGAVVAPLAVAVMAQVE -AGRLRLDDVVLIEDVDLSPPSAVADAWPGRNYTVQDLLERAVVQGDTTAADVLMKRVGGP -GAVTAWLQGRKVHDLDIARYQRQLLPASLADPRDTATPLGALRLLEALNQAELVGPDSRR -LLGRITSQAQGGSGRLRAALPDGARLAHAPATARTDLVGDIGVYTLKDGRKFAVVAFVSG -SALPVAAQEKAIADVGRVVIK-- ->[subseq from] serine hydrolase n=1 Tax=Caulobacter henricii TaxID=69395 RepID=UPI00055255A3 --qTMTAQFQPIADRVPGGLGVAVEDLGTGQVI-SFNGDRRFPLQGAVVAPLAVAVMAQVE -AGRLRLDDVVLIEDVDLSPPSAVADAWPGRNYTVQDLLERAVVQGDTTAADVLMKRVGGP -GAVTAWLQGRKVHDLDIARYQRQLLPASLADPRDTATPLGALRLLEALNQAELVGPDSRR -LLGRITSQAQGGSGRLRAALPDGARLAHAPATARTDLVGDIGVYTLKDGRKFAVVAFVSG -SALPVAAQEKAIADVGRVVIK-- ->[subseq from] serine hydrolase n=1 Tax=Pyxidicoccus sp. CA032A TaxID=2709663 RepID=UPI0013DCB382 ----LREGVDAAARDFDGELALYVRDLSTGEEY-ALNASTPMYLSSAIKVAVMLEVLRQVD -AGTLALDTPIAFEPDDARDMHPMAKVPPGTALTVATLLEHMMVHSDNAAADLLIGKV-GI -DHVNAGLERRGVHFGPLVSLLEDRHHAYYAEGTNSASMRELGQLLEQVARCEGLSPATCE -HAKSLMRSCDTGRARIRAGLPGTATWAHKTGTQHR-RACDVGILELQPGHPIIVAACTRG -FR-RVTEAEHLLARIGRTLTKAf ->[subseq from] Beta-lactamase class A n=1 Tax=Hungatella effluvii TaxID=1096246 RepID=A0A2V3XVZ7_9CLOT ---SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AHHEDERMMAASVIKLFVMTEAFVRFE -EGTLSSDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRMGYRDTVLQRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRQASE -KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETSLWLY--- ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus sp. hq2 TaxID=2039167 RepID=A0A2S3QDN6_9FIRM --------LREWIGTLPGIYGVFAKNLDTGKVF-TFNDTKVFPSASTIKVPILIELYRRVE -EEHLSLDHLLVMRREDQVGGSGVLKDLSPNTYSLRDLATLMITVSDNTATNLLIDFL-TI -EAVNITLRRLGVTHTELVRRLQRVPA-EPLDTVNHTTAQDMGLLMEKLATGTAISLAASE -QMVSLLKRCQG-PISITKLTAESIVIAHKTGSLAQ-ASHDVGIVYSPHLR-YVAALLSQG ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Microbispora sp. GKU 823 TaxID=1652100 RepID=A0A1V4EGH3_9ACTN ---------ERVFRSAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELHRQAE -RGLLDLSERVRVPAEDRTAGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLSRV-GR -EAVNTLLDGLGLTATRVVQNCRDMLTALDPALGNRSTPREMTRLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LSQNQPRADAAIGAAARMAIDQ- ->[subseq from] Uncharacterized protein n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=A0A3N9YAE7_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653V491_9GAMM ------------------------------------------------------------- ----------------------------------------------DNMAIVRLRNADAGE -PRLQALAEELVVPRADLDATLESVFDAYYRGDRNTATLAAFATVLDRLAAGELLSSDSTR -RMLDHMRAISTGDRRISAGLPPGTDFAQKTGTQLR-RACNVGVIDPEARNGATLVLACAE -DFDDIAQAETAFQGLGRALAD-- ->[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0664_bin_27 TaxID=2605260 RepID=A0A6B0Z0Z8_9CHLR ---SLESDIRNITANSGAEMAVSALHLESGQRF-DVDAERVYPLCSVLKIPVLVEAFRQIE -EGLFTLDDRWQLTTAEKNLPSGILVFFDDGLPTVRDLLTLMIIISDNTATDMVMHRL-GE -GSVTRTMHDLGLTDIHVPLTIRELFDYSLGPDNDTGTPAALTELLARIWRGETVSRAACD -TMLEILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GIRNDSGIIYAGESDHVAVTVFSRW -DDEA------------------- ->[subseq from] serine hydrolase n=1 Tax=Prevotella sp. RM4 TaxID=1200547 RepID=UPI00051B1A3F ----------------------------GGSVS-GINKDERFAMHSVMKFPQALYVADYLS -RKGLALDDTIVVDKADLMQWSPMLKQFERKMFSYAQLLELSLAQSDNNACELLFKHCGKP -KAVEKYIRKLGFYDIHVRMTEEQMHNNPAKAIENSSTPAEMVRLFEWLYYYKD-DNQYLT -FIWKAMADCSTGLKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMPDGSHVIIAVFTTN -SP-----SEAVIADIAKQLLE-- ->[subseq from] Uncharacterized protein n=1 Tax=bacterium SCN 62-11 TaxID=1660156 RepID=A0A1E4FZ27_9BACT -------RILTQLRQMPGEIAAYYQDLHTGRSW-GWNAEADFPAASVIKVPILLAVLQANQ -AGLLSLDQRVSVEFRHHVGGAGVLFEHDGAEMTVMDLCRLMIVVSDNVASNLLLDLL-PD -GAMAGLFRGLEMHRSLLGRRFMEQPR---PGHDNRTSAFDMGLCMAALARGEILDRSHTN -QALSILRRQQF-REKIPLMLPPELSVAHKTGELD-GVRHDVAVVEVPER-PYVLSLLTQR -GGHS-WDVDRALAELSLSVYH-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3MR35_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -GRIDALRNAMGMKATDLKRTIDDAYDRYYRAGLNAATLEGYGAMLEKLVRGELLSPASTQ -RLFKEMKIDIFTNYRLQAGLPRSVKFVHKTGTQYR-RACHAGVIEPQNGAHAIVVATCAA -DIDEQKAAGVVFERIGRAISQ-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI0011BF8304 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=UPI0008AA45CA ----LLARLQSIAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAITVLRGVE -RGDWNLDTRLTLAADDFVDGAGSTNQYGPGAVSVRALLEQMIIYSDNTATDRLIRLV-GI -DAVNQLVSELVPEGFEPITSLADVRRRYYSSNLNAARLTAFGKLLERLAYGEALGAEQTD -YLLGVMSRVKTGSKRIIAGLPKDARYAHKTGTQR-ARICDSGLIETSGTAEPVLVVACVR -GELSLAKAERTLRQVGEAL---- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=UPI0011C46E36 -------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILSPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---ETGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Larkinella soli TaxID=1770527 RepID=UPI000FFB79B6 -----REAVIRELENVPGTFAVAFRDLRTGEEL-LLRDREVFHAASMMKLPVMIEVYRQAA -EKRLSLSDSLLIDNASIVDGSPFRYGRIGGKRTLSSLVYDMIILSSNLATNLVIERV-GA -RNVTATARRLGARDLQVLRGVEDGKA-FAKGLNNTVTAFDLMQLLTVIAEGRAVGPEASR -AMIDILLDQRF-NTILPANLPKDVRVAHKTGWIT-GVLHDGGIVFLPDGRRYVLVLLSKN -VK-DEPAARQTLAKVSELVYRH- ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. C21 TaxID=2302915 RepID=A0A372F8I2_9BACT ----------------SIKVSMSVESVSGDKYF-TLRPDVTVPAASVIKVPILMELMEQVK -AKKINLNAIHILQASDKAGSSIIADKPAGTQLTIRELAQEMIHSSDNTATNILIKEV-GM -EDVNQNLMRLGSTKTKLNRIMLDTLA-VKQGRQNWVNALEINDLLRKIYNKKVATPALCD -EMIVILKNCRD-KTTIPRNLPEDLAIAHKTGELSY-VRGDAAIVYTK--QPFIISIFVEG -FK-DLSQAEQIIGDLAEICWE-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00026D67F3 ----FLAHIARVDEQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE -EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL -ERVNAVTRELVPEGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR -YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR -EAASTAKAERALRGTGEAVT--- ->[subseq from] serine hydrolase n=1 Tax=Rudanella lutea TaxID=451374 RepID=UPI0012FA68B0 ----------------SVRVSVALETLADSSVRlYHRADERVPSASLIKVPIMVEAMVAEI -EGRINLDEIHILLDSEKVGGSGVLKDYPNRSISYRDLVRLMITSSDNTATNILIGDL-SP -EAINARMRTLGLTQTGLNRVMMDTLAA-RQGRENIVTAREMNRLLTLIYRRQVATPALCE -QMLDFLKANED-SLTIPSRLPRQLVVAHKTGTLSY-VRADMGIVYAP--RPFVLSVIVEG -AGSD-IAAETVIAQIARLAYS-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A5D4TWD2_9BACI ----LEERILDAIDKCKGRISVAI-DLPS-HSI-QINSDTPYSAASLIKIPILLECFRQSE -HGKIDLDETVMVPKEYRVGGAGVLSTLSERILTVEDLLTLMIIVSDNTATNLIIDRL-GS -EAINNLCNSLALKHTKLSRKMMDFQA-MKQGYDNFTSASDIITCLRSLDQGTLFSQKSRD -KMLYILHQQQF-NTKLPARMDDKIYIANKTGELP-GVEHDCAIVRSEEKT-AYIVVLIDE -LDEN-ESARDTIAEIGKLLHDY- ->[subseq from] Class A beta-lactamase n=1 Tax=Duncaniella sp. TLL-A3 TaxID=2530391 RepID=A0A4Z0V6L8_9BACT --dALRDSISAIISDVTGEIGVAAI-IDSKDTV-TVNDIDKYALMSVFKMHQAVAICHSFD -LKGTPLDTIIEIDRTSLNPWSPMLKEHDNEHTPVSELLRYTLMQSDNNASNLMFDRLVSV -AETDSFIATIPRNSFRITERESDMQSDHSRSYNNHSSPLGVAMLVERLFTDSILSHEKQE -FICETMRSCSTGTDRIAAPLKDGITIAHKTGSGYINAHNDAAYITLPDGTSYTLVILVKD -FAGNEKQAAAIMARISDTVYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Thermoactinomyces sp. AS95 TaxID=1811386 RepID=A0A151Z1X9_9BACL --qKLSGSLDAWKKKSSGIWGIWMEDLNTGEKW-IWNEKQPFVAASMIKVPVMVAVYRAHA -LGKLCLSDRIELRREDRVGGSGVLQHLSYGTFTIQDLVTLMIIQSDNTATNLLIDRL-GK -EFVQETLLALEMTDTVFINRLHIVPAG--SNKTNQITAKDMARCFRLLATGQAVSRDASR -KMVEILKKQQW-RNCLPGRLPPSWEMAHKTGWVNQ-TLHDGGILYIASH-SLILVVLSSG -LDH--HQAQREINHIGKWVYDAy ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F776C22 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPKDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5BQ94_9BACT --------------------CVAFHDLGTGQTL-LRDADVVIHAASTMKVAVMLEAYRQHE -AKRLDLDRPMRVHAKSILDGSPYTYAHLGASLPTRDLVQRMMVRSSNLATNILIEAL-DA -SSVQETLGSLGCRDMKVLRGVEDTP-AFEAGLNNVTTARDLMLLLHAIHEGRGVSAASRE -AMIATLRAQEF-NDLIPAGVGPGTPVAHKTGRIT-GIRHDAAIVYPKDRSPYVLVVLTRG -FD-DSEAAGAVIREISRTVWTH- ->[subseq from] serine hydrolase n=1 Tax=Runella limosa TaxID=370978 RepID=UPI000687B766 -hpALEQSLADYLAKLPVKVNYRVESLEGKRYA-SLGDDERVPSASIIKIPILVEVMEQVK -AQRFELTDYYTLQNADKVGGAGIFQEREGKAFTYEQLAHQMMVASDNTATNILIRKV-GR -EAVNERMKTLGFPNLQLNRVMMDTAA-VAKGIENYVNAAEINRLLSLIYQRKVATPALCD -LMVAFLLDNHD-TSTLPSLIPRQVGIAHKTGTLTY-IRGDAGIIFTK--KPFVISVFVRG -TEL--NRAETIIAEIGKISYE-- ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2D9TMW2_9BACT --pSLQNNIEKIIKSEKGKFAVAFKNLEDGQVI-LINEMEEFHAASTMKTPVMIEAFKKSF -ENKISLDDTILIKNESIVDGSLFKYERIGGHLSLRELIYEMITISSNFATNLVIDYI-GH -EDINMTMRDLGAKDINVLRGVEDIK-AYNKGLNNTTTALDLLKIYENLALGRVINTKLSQ -KMVDILKDQKY-DDIIPKYLPKEIEIAHKDGWVS-GTRHDSGIVFINDEKKYVLVLLSKN -LE-DEIKGADILAKVSLEIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. CACIAM 22H1 TaxID=1812911 RepID=A0A162QSX9_9BACT ----LDKAIRAEMSKHQAEFAIACKDLGTGQTY-FVAEKKSFHAASTMKTPVMMEAYKQAA -AGKFSLQDKITVKNSSIEDGSVFSYQLIGKELPISDILHRMITKSSNLATNIIIDLV-GA -KNVMTTMKEIGANQIQVLRGVEDKK-AFEAGKNNTTTAYDLMRVFEELGNGSFISKMACA -DMIRVLQDQYF-RNSIPAKLPREVKTATKSGSIVK-ITHDSGIVYLPDGRKYVVVLLSKG -IE-SQEEANAALAELSKLIYDE- ->[subseq from] Beta-lactamase domain-containing protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1R282_9ZZZZ ------------------------------------------------------------- ----------------------------------------------------------GGP -RELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI0011A60AC4 -------EMKQLLGDLKGKAGAAIEI--DNDCF-YFNHEEVFPSASVIKVPILIEALRQAE -SANIDVNESIQIRH--RVGGSGVLQALSDQVVTVKDLMTLMITVSDNTATNMMIDLL-GM -DAINTTIKNMGMQKTVLQRKMMDFS-AIERGLNNLTSPADIVTCLKVMNQGDFLTEKSRK -LALEIMHAQQFHD-KLSAMIPEAIFVAGKTGSLPQ-VENDCAIFKWGNKT-AYVAVLMDQ -LE-DSYSGRRVISKIGKYLYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Odoribacter splanchnicus TaxID=28118 RepID=A0A413I971_9BACT --------------------------------------------------FQAVTALKKME -AENIPLDKMVYIKQKEMLKYSPLRDKYPDQGISYRDIIKYTVSISDNNTCDWLIRFVGGI -DKVDSYIKSLGIKDMNFTETEESMHTDIMLCYNNWSTPLAIAQLLKKLHTENILTKEHFA -FLETAMLDCVSGKNKLIAGLPTDIKFGHKTGRSNRTSEGDAGVIYLPNGEKCYIVVLIKD -SRESDDDNAKIMADISNIVYRH- ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI001243E25C ---DLERRLRSIDARYAGDIGVYVHHLGRDEAW-GFRADEAWYLASGVKVPVAIAVMREIE -QGWLTLDTRVALLDTDFVDGAGRTNAHRAGTLSISFLLEQMIIHSDNTATDVLIRVV-GL -GQVNAVAHELIAAQGVQITSLADVRRSYYATHVNSATLRDYGRMLASLQRGLAVDGDSTR -YLLDVMGRVQTGRQRIRAGLPAGASFAHKTGTQYR-RLCDSGIVTMPGGRPVQVVVAACV -RGSAGAAGERALRDIGAAVT--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000775B61D ------------------------------------------------------------- ------------------------------------------------------------- ----EALARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase (Penicillinase)-like protein n=1 Tax=Ramlibacter tataouinensis (strain ATCC BAA-407 / DSM 14655 / LMG 21543 / TTB310) TaxID=365046 RepID=F5XZA3_RAMTT ------------------------------------------------------------- -----------------------------------------------------------GP -ERVEAVRRALDMPASALQATMAQAYDRFYENNLNHATLEGYGRMLERLVRGQLLSPRSTE -RLFGYMKFGRRGDYRLEGGIPRSEPIIHKTGTQYR-RACHMAVVNPQGGAKAIVVATCAA -DMDDVREAGGIFRQVGEAVS--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 50-39 TaxID=1895841 RepID=A0A1M3H548_9SPHI -----LQKIDSIFRSQPGSFALAFKDLSTGRQL-FLHEHETFHAASTMKTPVLVEIYRQAA -IHRLSLTDSIVLKNEFISISSAYQYRHVGEKRSINDLVYQMITVSSNFATNLLIARV-GQ -ANIGVTLHKLRLDELHVLRGVED-NKAYQKGLNNTVTAAGLAELFEKMAKGRLVSRQASK -DMIRILMDQHF-NDIIPAGLPAGTKVAHKTGWIK-GVHHDSGIVFLPDGKKYVLVLLSKD -LA-DDKAGANALAAISAIIYQY- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridia bacterium BRH_c25 TaxID=1734399 RepID=A0A101WEB2_9FIRM -----------NIKKLKGTVGVYYKSLTTGGTL-SFNEKKSIISASVIKVPVLVEAFHQME -IGTISKDEVMTLCDDDKMPCGALSYMHSGLEVTVEDLCKLMIILSDNTATNMLVKRL-RF -DNINGYMQELGLKNTFLGRLLFDMEAD-KKGSRNVISAKDIGMLFEMMWQGKLISSAASR -QMLDILKLQQF-SHKLPAKLDEEVAVAHKTGEDT-GITHDAGIIYAP--KPFILCVLSEG -TD--AVETNAFISGLA------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DD79BBF -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 03113 TaxID=2578211 RepID=UPI00114226F3 ---KFKSNINDHVKKCQGRVSIWIEM--DKEII-EINSKQAYPAASLIKVPILIEAFRQKE -EGKLDVEQLVSISKEEKVGGAGVLFSLSSKAFTIHDLMTLMIIVSDNTATNQLIDLI-GW -HEINQCIKALNLTSTRLNRKMMDLD-AIKLGKDNWTSAVNIGTCLKEIYKGSLLSKESKE -EILSMMRKQQF-KEKLPAYMNKGW-IANKTGELE-GIEHDCAIIQYNGI-TVYMAVLIDQ -LSAQ-EDGRETIRQIGKLVNN-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D4II70_9BACT ---TLKTDLLQLIAEYSATVGISVIDWTNKQSI-NINGDVRMHAASTMKIPVMIEVFRQTT -VRKLRLKDSLVVKNESIVDGTHFAYRELGKKKSYYDLVFQMITVSSNIATNILIDDL-GA -QNVQQTIERLGTTQMKVRRGVEDTK-AFERGLNNEATANDLALLLTRIAQGKAVGKEEDR -AMIDIMMAQRF-NEMIPKGVPNGVKVAHKTGEIT-AHRHDAAIIYPEKGKPYTLVILIKG -IEDS-EKAYQLGINISQK----- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DDB4EE5 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DDBB526 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DD5A68F -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudoxanthomonas wuyuanensis TaxID=1073196 RepID=A0A286CYN6_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALAQALGVPRSELDATLDALFENYYRRGDNSATLRAFAAVLEQLAAGQLLGPESRQ -RVLGHMRRISTGARRIQAGLPEGADFAQKTGTQI-GRACNLGIIDPDRGDGAVVVVACAE -RFDALAEAEQAFEQLGTALVD-- ->[subseq from] class A beta-lactamase n=1 Tax=Prevotella sp. P6B1 TaxID=1410613 RepID=UPI0009DCDBE5 --------------------------MRDGSFV-GINENEHFAMHSVMKFPQALCVADYLS -RKGLDLDDTIVVDKADLMQWSPMLKRFECKTFSYAQLLELSLGQSDNNASELLFKFCGKP -KAVEKYMRKLGFHDIHIRMTEEQMHKNPAKAIENSSTPTEMVRLFEWFYHHKD-DNRYLT -FIWKAMADCSTGQKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMPNGSHAIIAIFTTN -SS-----SEAVIANITRQLLD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter luteus TaxID=572036 RepID=A0A1T5AAU9_9SPHI --qKTERQLQDIVSSSPFLTGMMAIDLTTGDSF-SSNQDIVFAQASAIKIPILMEVYKQAK -ENKFALTDTRPLLTTNTVAGSGILNAMVDPVLSIRNYCMLMIGLSDNSATNTLIELV-GL -NNINNTMQSLGLKNTRVQRKMIDQPASIR-NEENISTPAEAAKIMKLLYDGKFVDKATSD -EILLTLQKNPVENSKLVRGIPSGVKIAFKPGGMG-GVSTEWGIIYLAKK-PYAVAVMENY -KA--GPSNQDVFANISKVLYDYy ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Clostridium roseum TaxID=84029 RepID=A0A1S8KYD7_9CLOT ---ALDNAIKNILALRCEDISLVFLDLNNTSNYiYINENKIFPSASTIKVLILAEALNEVL -NGKLSLDAPIEVKTSDKVPYSILTS-LTNNKYPLIDLLTLMIISSDNTASNILIDLL-TM -ESINNYGQSIGLKNTSLKRKMMDSKA-VQRGMDNLTSAFDMLTLFKKIYNHELLNPKMCD -LILKILGDNTD-KEVLLRYLEADIRCAHKTGDLSN-LNHDIGVFKTKTS-EYILGVFVRN -ADFN-YVAKDLIGKVSKIVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus sp. OK028 TaxID=1884359 RepID=A0A1H0F2A3_9BACI --kELVSRVQQLIAASKGTWGIVLEDLNSGERW-EHNEQELFYAASVIKIPIMSSVYSAVD -KGDLTLNDLVVLDKKDYVGGSGVLQHFTPGSLPLQDIIMLMIIQSDNTATNLLIDLV-GV -ENIQNSMKEADMFYSTFYNKLMLSKPN--PEGTNCIAALDIAMLLNKMASGSLVSRTASE -QMIDVMKKQQV-RDCLPEKLPSPWELANKTGWIP-GTRHDVGIFYVGNRK-LMATVLSKD -ED--DLVSKRILSQIGEEIYKY- ->[subseq from] Beta-lactamase n=1 Tax=Chthoniobacter flavus Ellin428 TaxID=497964 RepID=B4CW47_9BACT --qALHDRIESLRTGSGAAIGVQVFDYETDRTF-SHEGDRWFHAASTMKVAVLLALFHAVD -TGRVRLEDRLHVRNRSIVDRSIFRHRRVGRSMKLIELAEPMITRSSNLATNLLLEFL-TP -DYIQSTLTAAKVDGVRVLRGVEDSV-AFDRGLNNTVTPSGLVALFRLLRENRLLPESARN -RMLAILLAQEF-NSMIPALLPDSAQVAHKTGEIST-CTHDAGLVLLPGRRPYAVAILTEH -PP-GLDDTQKLVAKVSRLVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-096BSC TaxID=1729725 RepID=A0A0T6VR87_9PSED ----FLAHIARVDEQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE -EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL -ERVNAVTRELVPEGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR -YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR -EAASTAKAERALRGTGEAVT--- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A354WLY6_9FIRM --kDLASRLSAVMDAFPAKTALYCVDLTTGTPIaAIRENTRVVSASTIKVPILCCALQDVM -DGKLSLDQHLAIAPADFCSDTEVFEPYRQDGASLWEMLYWMIVSSDNTATNTIISLL-GH -DHVNQYCRTIGLTQTSLQRKMLDFQ-AIAEGRNNYTSPADLYRVFSLLYHGEILNKPLRE -VAFDFLSRCRS-TDALQRYIPDAVTVLHKPGGLDH-LNHDAGIFLTEDR-PYYLGIFTWD -GPDGQPQQNRLIGQLSRMIYDA- ->[subseq from] Serine hydrolase n=3 Tax=Runella sp. TaxID=1960881 RepID=A0A3C1TIM4_9BACT -hpALEQRLADYLAKLSVKVNYRVESLEGKRYA-SLGDDERVPSASIIKIPILVEIMEQVK -AQRFELTDYYTLQNADKVGGAGIFQEREGKAFTYEQLAHQMMVASDNTATNILIRKV-GR -EAVNERMKTLGFPNLQLNRVMMDTAA-VAKGIENYVNADEINRLLSLIYQRKVATPALCD -LMVAFLLDNHD-TSTLPSLIPRQVGIAHKTGTLTY-IRGDAGIIFTQ--KPFVISVFVRG -TD--LNRAETIIAEIGKIAYE-- ->[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A374NY34_9CLOT ---SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE -EGTLSTDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTAANVLIDLL-GI -EEINRTIRRMGYRDTVLQRKMYDTEKS-KWGIQNYITAAETGRLLREMYQGRLVSRQASE -KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETSLWLY--- ->[subseq from] serine hydrolase n=1 Tax=Psychrobacillus sp. OK028 TaxID=1884359 RepID=UPI000B875024 --kELVSRVQQLIAASKGTWGIVLEDLNSGERW-EHNEQELFYAASVIKIPIMSSVYSAVD -KGDLTLNDLVVLDKKDYVGGSGVLQHFTPGSLPLQDIIMLMIIQSDNTATNLLIDLV-GV -ENIQNSMKEADMFYSTFYNKLMLSKPN--PEGTNCIAALDIAMLLNKMASGSLVSRTASE -QMIDVMKKQQV-RDCLPEKLPSPWELANKTGWIP-GTRHDVGIFYVGNRK-LMATVLSKD -ED--DLVSKRILSQIGEEIYKY- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA1(2017) TaxID=1932113 RepID=UPI0009697C3F ----LLERLRATAAKQDGELGVYVKDLHSNLAV-TLQAERLWYMASGIKVPVAIAVLRGVE -RGDWQLDTHLPLAANDFVDGAGSTNQYGPGELSVRFLLEQMIIYSDNTATDRLIRLV-SL -DAVNALVRELAPEGFEPITTLGDVRRAYYRSNLNAATLSAYGELLERLADGQALGQAQTA -YLLEVMGRVKTGSKRIIAGLPKDAHFAHKTGTQR-ARICDSGLIRTPEREPVLIVACV-E -GELSLAKAERTLRQVGEAL---- ->[subseq from] serine hydrolase n=1 Tax=Thermoactinomyces sp. Gus2-1 TaxID=1535750 RepID=UPI000504E565 --qTLTGSLDAWKKKASGVWGIWMEDLHTGEKW-IWNEKQPFVAASMIKVPVMVAVYRAHA -QGKLCLSDRIRLRREDKVGGSGVLQHLSYGTFSIQDLVTLMIIQSDNTATNLLIDRL-GK -DYVQETILDLEMNDTVFINRLHIVPAG--SNKSNQITAKDMARCFRLLATGQAVSRDASQ -KMIEILKKQQW-RNCLPGWFPPSWEMAHKTGWVNQ-TLHDGGILYIASH-SLILVVLSSG -LDH--HQAQREINHIGKWVYDAy ->[subseq from] ClassA_beta_lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059XDF9_9BACT --eSLQSRIEKEFSREQGEFALAFEDLATGEQL-LINAGERFHAASTMKTPVMIEVYKQVA -EGRMSLHDSVEVKNTSIVDGSAYSYKQLGHKRTLYSLMYDMIILSSNLATNLVIERV-GA -IHVTATMRGLGAKDIEVLRGVED-NKAYEKGLNNTITAYDQLLIMKKIALGKAVSKEASD -AMMNILFDQRY-RDIVPANLPPEVKVADKRGWLT-GLEHDCAIVVLPNGHRYVLIILSRK -LV-DRDKAVKAMANVSRIIFDH- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-096BSC TaxID=1729725 RepID=UPI000AE48A6D ----FLAHIARVDEQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE -EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL -ERVNAVTRELVPEGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR -YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPTASRRLLIVACVR -EAASTAKAERALRGTGEAVT--- ->[subseq from] Serine hydrolase n=3 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6B535_9BACT ---TLDEQVERLAAESKARIAIALHDLESGLRF-SLRGDRWFHAASTIKVAVLLSVFRAVD -EGRFRLDDSLHVRNRFISVGSPFYYQAIGQTAKISALAEGMISSSSNLATNLLLDLL-GV -EYARKVLRDAEVEGVELRRGVEDH-AAHEKGMNNEATANGLLTLLSA-VRGDFLSSESKE -QAIRILLEQRF-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DP-EREGRRETVAAISEAIYR-- ->[subseq from] Serine hydrolase n=2 Tax=Nonomuraea TaxID=83681 RepID=A0A5C4WYA4_9ACTN --------FDALFRGAGVTGWLYAADIDSGHEV-GHRPDEPLPTASMFKVPLLVALCRQAD -AGLFDLSERVTVTDADRSPPTGIAAMLDDVTISLRDLAYLMITVSDNTSADVLLGRV-GF -EAVNDMLAAFGLEGTRVTQTCRQLDDVLDPARTNRSTPRELARLFAMIWRDEAASAESCA -WMRGVFNMQVW-PHRLASGFPDDVAVGGKTGTLPT-LRGESGVVEYPDGRRYAVAVITRS -FSLNQPRADAAIGTAARMAVDH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=A0A100WDY1_9MYCO ----------EAELRHQARIGLYALDLKTQNTI-THRNHDRFAMCSSVKTYVAARVLQKAE -RGELALTDSVTVHGADIVPNSPVTETWVGRSIPVAELCAAALQKSDNAATNYLLKTVGGP -SAITEFARSIGDNETRLDRWETELNSATPGDARDT------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2D5QJZ8_9BACT --nNLENKITNLLKSHKGSFAVALKNLDNGNTI-LINENEIFHAASTMKTPVMIELFKKKH -NGEISFDDSLQIKNESIVDGSKFEYKNLGEYISIRELIFDMITKSSNFGTNLLIDYI-DV -KNVNNTMRDIGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGSLINPSTSN -EMVEILKNQVY-KDIIPKYLPDNVKVAHKTGWIS-GVRHDSGIVFLENGKKYVLILLSKN -LDD-DIEGAEFLAKISLEIFN-- ->[subseq from] Serine hydrolase n=3 Tax=root TaxID=1 RepID=A0A512TPN4_CLOBU ---ELNEKIKEIINESGTDIGILVKDLTNDKVIvNYNENKSYVSASLIKIPIFIEALRRVD -NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL -DNINNTVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR -RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN -VNN-NLEGCKIIGSISKVIYEYf ->[subseq from] serine hydrolase n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=UPI000F5EF0B4 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=bacterium HR16 TaxID=2035411 RepID=A0A2H5X0C0_9BACT ---ELFQALFEKIRSVPAEVGLAVRGVDIDLRI-DINSIEPFRSASVIKVPLLAALFWLSE -QGKLDWQERLALRDADRTPGSGILREHTGLNLTLHDLAVLMIVLSDNTATNMLIDRV-GV -ERVQEFLRLVGFHHTTLQRKMYDFAAA-EQGRENLCCAAEIADLLKWMAQGELVSGAGCE -QMLHIMRGQFY-RDQIPALLPDEAKVANKTGEIR-GHHHDSAVVWTPAG-CYTLVVLTRG -FE-HRRVAASFIAELSLMIYR-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella bivia TaxID=28125 RepID=Q8KT60_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTKEEMSADHNKAYSNYTSPLGAAMLMNRWFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Muricauda olearia TaxID=552546 RepID=UPI001261F2CD ----LEDKVHAQIDSIEGNVAVAFLNLSDPSDTlYFNENEEFHAASTMKVPVMIELFKQKE -EGKINLNDSILLINESIVDGSSYSYNKINTQVALKDLMYNMITVSSNLATNVLIELV-DA -KKVTATMRDLGAENIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCN -DMIAILKDQRF-NDLIPRDLPKNVEVAHKTGWIT-GVHHDAGIVYLPDGQSYVLVLLSKN -IQ-DSDKGTQQLADISKAFYDY- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A4S2BCQ0_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLKLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax konjaci TaxID=32040 RepID=A0A1I1UN64_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQAVARALEVKKADLKGTMDEAYTRYYTRGLNSATLAGYGGMLEQLVRGRLLTPENTQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQWH-RACHMGVIDPQDGARAIVVATCAE -GLDEMRQAGRLFEQLGRTIT--- ->[subseq from] Beta-lactamase n=2 Tax=Francisella hispaniensis TaxID=622488 RepID=F4BKG5_9GAMM ------------------------------------------------------------- ---QGFLDKKIPITQDDIGTYAPITAKNIDKSLTISQLNYAAI-LSDNPAANILVREIGGL -QNLNKFIKKLGDKDTIIIADEPKVNHTKPDSNINKTTPKAITKDIYKLAFGNVLDKKHKD -IFIKYLQDNNTGANRIAFSMPKDWIIGDKTGTCGYAATNDVAIIWPKNQQPIGLGILYTN -PNKNAPSNEEIIQQAAKLIAN-- ->[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A3E3DPI8_9CLOT ---SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE -EGTLSPDRIIRMKREDCVPCGALTYLHDGIQVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE -KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDCE-ITHDVGIVYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETSLWLY--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7959A8 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0002E8BD82 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Serine hydrolase n=2 Tax=Pseudomonas sp. TaxID=306 RepID=A0A352HXI2_PSESP ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A6A9R0X7_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Salinicola peritrichatus TaxID=1267424 RepID=UPI000DA215A0 ---RLEARLTEIDRQYAGEIGVHVRRPATDERL-GHRDAERWYWASLVKIPVAVELLDRVS -RGDIDLQERMTLAQSDYVDGAGATNWEPGSEIRLRTLLERMLIQSDNTATDMLIRRV-GL -DAVNHRARRLMSDGIGPITTLVDVRRRYYATGLNSGRLDRYADMLARINAGKALDGEATQ -VLLEIMRRATTGHARLAAGFQREWPFAQKTGTQH-ARFCDAGIVNPRTSRAVIIVSCLKG -DP-SRQNANRTFQAIGEAI---- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7AEBAD ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00030A0F2B ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax valerianellae TaxID=187868 RepID=A0A1G6XR34_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -KRLQALARSLDVAAGALNKTLDEAYDRYYRHQANTATLEGYGAMLEKLVRGQLVSPAHQQ -LLYKDLKFDTYDAYRLEAGLPRSVRFIHKTGTQFH-RACHMGVIDPQNGRRAIVVAACAE -GLDEMKEAGKAFEQIGRAITQ-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000E5C837E ---TVEGTIKDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAETTVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas stutzeri (strain A1501) TaxID=379731 RepID=A4VI25_PSEU5 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004C166EE --------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQIFLDDGVLVTPEDVVGGSGQLQFETFPQVTVHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO31t TaxID=2650566 RepID=UPI00124B0BB4 -------RIVAAAGTTGNLAGVTVRDLSGGQQV-SVDGRFRPRAASVIKLWIVTELLRRVG -CGQVSLDQRVLVTRADVVGGTGQLQEEIPQLASLYKLAQYTIKYSDNTAANVLINYLGGF -APVNALIDSMNQRETVLARKFLDAEA-VARGEENYTSPDDVISLLGAVWDAQILDPASRD -LLIGFMREQTL-NTKIPAALPPGTPVAHKTGDLPD-VSHDVGYYLIPGEE-TAVAFLTSG -PQ---ATGDQVVRCLARAVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7X8D7_9BACT -------------ERHGERLGIAFWDSETTLQW-AYNADEYFHAASTMKLAVLLGVYRQVG -RGELTLDAPVHVRNKSVVNDQLYMYRNLGRTMTVQQLAYAMITTSSNFATNLLVDVL-GV -STIQTALAELGIDGMKVVRGVEDQ-AAFEAGINNEVTAAGLLKLLRALAEGKAYGAEASA -EMLKILHDQRF-KGGIPAGLPQAARVAHKTGNIAT-VHHDAGIVYLEHRKPYALVILTQF -HSE--TPRSTAVADVSRDIYE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Muricauda sp. ARW7G5W TaxID=2135618 RepID=A0A3D9EQA8_9FLAO ----LEDKVHAQIDFIDGNVAVAFLNLSDPSDTlYINKDEEFHAASTMKVPVMIELFKQKE -EGKINLNDSILLINESIVDGSPYSYNKINTQVALKDLMYSMITVSSNLATNVLIELV-DA -KKVTASMRDLGADNIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCD -NMVDILKDQRF-NDIIPHNLPKDVEVAHKTGWIT-GVHHDAGIVYLPNGRSYVLVLLSKN -IQ-DSDKGPQQLADISKTFYDY- ->[subseq from] serine hydrolase n=1 Tax=Prevotella sp. P6B4 TaxID=1410614 RepID=UPI0009DDDB79 --------------------------MRDGSFV-GINENEHFAMHSVMKFPQALCVADYLS -RKGLDLDDTIVVDKADLMQWSPMLKRFECKTFSYAQLLELSLGQSDNNASELLFKFCGKP -KAVEKYMRKLGFHDIHIRMTEEQMHKNPAKAIENSSTPTEMVRLFEWFYHHKD-DNRYLT -FIWKAMADCSTGQKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMPNGSHAIIAIFTTN -SS-----SEAVIANITRQLL--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A431RKQ6_9BRAD -------ELESYERESGGRIGVYAENSATGKKL-SWRADERFVMCSTFKASLAACVLARVD -RGEEQLAAMIPYGKADLLDYAPVAKQNLAAGMSVTDMCKAVVELSDNTCANLLLARIGGP -ATLTAFWRSLGDSTSRLDHNEPELNRSPPGNPQD-------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Bacillus fortis TaxID=254758 RepID=A0A443J0I9_9BACI -------EMKQLLGDLKGKAGAAIEI--DNDCF-YFNHEEVFPSASVIKVPILIEALRQAE -SANIDVNESIQIRH--RVGGSGVLQVLSDQVVTVKDLMTLMITVSDNTATNMMIDLL-GM -DAINTTIKNMGMQKTVLQRKMMDFS-AIERGLNNLTSPADIVTCLKVINQGDFLTEKSRK -LALEIMHAQQFHD-KLSAMIPEAIFVAGKTGSLPQ-VENDCAIFKWGNKT-AYVAVLMDQ -LE-DSYSGRRVISKIGKYLYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DDAF706 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPSGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Lentibacillus jeotgali TaxID=558169 RepID=UPI0002627C2B --kQLESEIFSIISDINSPIGLVIKE--GHHSI-AINESMPMPAASVIKIPIIMEAFRQAE -NSGLNLSETLRVPTDAKVGGSGVLQSLSEDAMTLLDVLTLMIIVSDNTASNLALKRV-GI -DNVNRLCHELQCHNTEIQRCFMDMEAA-EKGLENTTTAGDMVKLLAEIAAPNLLRKESAN -SILHIMTQQQLASKLPAYHVNDDVIIANKTGELAH-AEHDVGIFQYQDRT-VTAAVLMVG -NS-DHVAAQHAIARIGKVIMAY- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000651B294 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7A74C4 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Uncharacterized protein n=1 Tax=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 TaxID=1798438 RepID=A0A1G0SJH1_9BACT ---KTEVGIREAVNGVKGAAGLIAIDLTNDDTF-AVNENMVFPQGSAIKITVLMEVYRQAA -KGMLTLTDTHPVTAQYQVGGSGVLQTLGDGTLSVRDLCVLMITLSDNTATNMLIDLV-GM -NNINSTLSGLGLKETRVQRRMIDIPAS-KRGEENLSTPAEAARIMTILYKGEFVDRKTSD -AILDILKIPKR--GTINAEVPETIKVAFKPGGIS-GVSTEWAIVYLPQR-PYIVVAMENY -SVGD--EASDMMRKASRLMFDYf ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3B9TKZ3_PSESP ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=UPI00115934EE --hKLTAKLQALVANFQGEAGIYVEHLKTGRFV-AINADTVFPTASIVKVPLLVGLFDKIE -KGELKYHQPWTYRDSAKYGGSGIMQFFRDSATEVSVLAALMMSYSDNTTSLMIQSMAGGG -ARVNELMEQYGLKDTRVNSRTPGRAEIWKKYGWGQTTPREMARLVTMIRKGEIISPAAGD -RMYRLMCRGYY-DESSLSQLPPNVQAAHKTGSVD-ATRSEVVLVNAPHGD-YVFHIATKN -NKSDDNEAVVLIRNVSATIWNHf ->[subseq from] serine hydrolase n=1 Tax=Acidovorax konjaci TaxID=32040 RepID=UPI000B846025 ------------------------------------------------------------- -----------------------------------------------------------GP -QRVQAVARALEVKKADLKGTMDEAYTRYYTRGLNSATLAGYGGMLEQLVRGRLLTPENTQ -MLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQWH-RACHMGVIDPQDGARAIVVATCAE -GLDEMRQAGRLFEQLGRTIT--- ->[subseq from] Uncharacterized protein n=1 Tax=uncultured delta proteobacterium TaxID=34034 RepID=A0A212IYG9_9DELT ----LQKDLETLSKNVHGRVSYIVASADGALDL-RRGEKDRFPSASIIKLPILWSVFSKAA -KGELALTEEMPLRAGDIVDGYGVLKMHVGIGTTIEDLCFLMTVTSDNVATNMLIDKL-GF -AAINADIAACGMPDTVLGRKMLDAEAR-AQGRDNFTTPLDVLTFLKMLRHGGTMPENSRA -RMLAIMHNQCC-NNFIPQYMPEGFRFAHKTGDIQ-GTVHDAGILYGPSGREYYVIVLCSD -LAD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000BA94384 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00105B26E4 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=A0A560AX33_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILAPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000D229E0D ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Microbispora hainanensis TaxID=568844 RepID=A0A544YKS0_9ACTN ---------------AGVMGWLHAVDIDDGREV-GLRADEPVVLASVFKVALLLELHRQAE -RGLLDLTERVRVPAADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNALLDGLGLTVTRVTQDCREMLTALDPAVANRSTPREMTRLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -YGQNQPRADAAIGTAARMAIDQ- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:924 TaxID=1262938 RepID=R5FRD0_9BACT ----LTDSISQIVSACPGEIGVAVI-INNTDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRGKLNLWSPMIKDYSEPILTVRDLLRYTLTQSDNNASNFMFKDIVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIGDEKQS -FIKNTLKECKTGVDRIAAPLKKGVTIAHKTGSGYNGAHNDVAFICLPNNTCYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5GQC0_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A0H3YV17_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Eubacterium sp. TaxID=165185 RepID=A0A1C6L793_9FIRM ----LKEQLIAYLKKENVQGAFLIKDLSDGETL-CHNECLKVPSASLIKMYILVEAFRCIK -IGSLTLDKEIAVKKEDLVDFSVL-QFLRPRLYSLEELLSLMVVYSDNTATNVLVDYF-GM -ASLNELMQQIGCRTSVIQRKMMDFAAA-EEGRQNYTSVMDMTSLLERLYQGSLLGQPFDA -QMLDIMKGQAD-EEAMRRDLPDELVIARKSGELD-ALDHDIAIVYTEKRN-YIYVFFSWE --TGDNNCGRKVLAETSKLVFDYf ->[subseq from] Serine hydrolase n=1 Tax=Pigmentiphaga aceris TaxID=1940612 RepID=A0A5C0ASD4_9BURK ----LLPALQDIAARANGDLGVSVIDLVGGASC-AVRADDSFPLHSMVKLVVAASVAYRIE -QGAFGLQTLVALSQATRPGGVGPLREQGDQTASVERLLEAILLYSDNAACDGLMALVGGP -SVINADLRRWSVADMRVDRTMRELYAAWLADPRDRTTPTAYADFARRLAGGSLLGAQATS -IVMNGWQRSTLTPNRITAGLGAGWSVASRSGTGPTTSTNHAVLATSPAGRPVLVAAFLRN -AAGADAERAMVLADVGRAVAT-- ->[subseq from] Beta-lactamase n=1 Tax=Akkermansia muciniphila CAG:154 TaxID=1263034 RepID=R6J0V1_9BACT --------------------------------------------------MLALSVLKRVD -QGAMNLEQIIRIRPEQLVKWSPLRERSPQGGFSLKELLRVTVQESDNNTCDLLFSLIGGP -QAVQKDLTEWGIDGINVRFTEDEIHRNRDLQYANSSRPSAMNSLLRAFDEGKILKKGTQR -FLWDIMAGCSTGHERLKGQLSRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRMIASMARWLCMEw ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A368CSD1_PSESP ------------------------------------------------------------- ------------------------------------------------------------- --------RVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus panacihumi W25 TaxID=1408254 RepID=V6M611_9BACL ----LKKQLSQIVEDAKGTWGIVVEEIGQGICF-EHLPDQSFIAESVIKVPIMAAVFAAAW -QGEFSLEDRLALRREDMVHGSGMLFALSPGLLSIRELATLMIIQSDNTATNILIDLV-GK -ERIEQTMRELGMKESRYVRKLMIYPADNPG--NNTITARDVTTMLSRLGAGRFLSAKACE -EMVDIMKKQQF-RNGLPSLLPTDWEIACKSGWDT-GRQHDAGLLYVQGR-CFAITALSQD -VE--AEEALHTLGSIGKAVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=A0A427SHQ9_CLOBU ---ELNEKIKEIINESGTDIGILVKDLTNDKVIvNYNENKSYVSASLIKIPIFIEALRRVD -NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL -DNINNIVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR -RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN -VNN-NLEGCKIIGSISKVIYEYf ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus saniviri TaxID=931533 RepID=UPI0006CFC593 --------------------------------------NRPQRAASTIKLFILATAYAKVS -RGQFNLDQHYTLQETDKVGGTGVLGGQAAGTLSYRDLLNDMITQSDNTATNIIINLVGGM -PAVNAEIRQLGARDSQLNRKMMDTAK-LTAGVDNVTSVQDVGHLLQRLYRHQLLSADADT -QMLNILQRTQN-HSKLPASLPATATVYNKTGEFDYGVQNDAAIIADKKGA-FVAVVMCQN -GNE--AAQISAMRQLGSALY--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium MT.SAG.3 TaxID=2552982 RepID=A0A4Y8I409_9BACT --------------PAGSEVSVAYENLQTGSKM-FVNAKEQMHAASTYKTALMIEVYKQTA -EGKISLTDSIDVVNSSIVDDSEYAYELIGKKASYFDLTYQMITVSSNLATNLLMNEV-GA -KNIMKTLESIGVKEMQVLRGVDDLK-AYELGLNNTTNAEDMLRLMIAIAKDEVVSPSACA -EMRKMLLAQVD-NSKIPAKLPKEVKVAHKTGSITK-IDHDVAIIYPPKGPVYSLVVLTRG -IK-EHKDAEELIADISKIVYD-- ->[subseq from] Serine hydrolase n=2 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A210Y0F6_PSEST ------------------------------------------------------------- ------------------------------------------------------------- --------RVLNLRQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase class A n=1 Tax=Singulisphaera sp. GP187 TaxID=1882752 RepID=A0A1N6I0A8_9BACT ---TLESRLMPLIQAHKGKVSVAIKNLKTGETF-LYHEDVPMPTASLIKLPIMVETYRQAE -EKKVDLGEMITLKQSDKVPGSGILTDHFSAGFPLLDAIHLMIVYSDNTATNLVLDKI-GI -GSTAETMEKLGYPHTKAHSKVFRRDTRSKQFGLGSTTASEMIRLCESLQKGELISKEASE -AMLKHLRACDD-KDKFPRFLPPGTKVAFKTGSVD-ASKTAAGLIECGQG-PVAVCVMTDE -NEVTDNAGNRLCAEVARVVFEHf ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas sp. Mitacek01 TaxID=1732019 RepID=UPI0006DBA61E ---ALDRRVRAIDARLTGEIGVHVQRLDGGTQY-GFRASEVWYLASGVKVPIAIAVLREIE -QGWLTLDTQVTLRADDFVDGAGGTNAHRAGDLTIAWLLEQMIVHSDNTASDVLIRTV-GL -GQVNAVASELIARDVRITT-LADVRRSYYATHANSATLRDYGHMLAALQAGDALGPDGTR -YLLDVMARVQTGKQRIRAGLPAGARFAHKTGTQYR-RICDSGIVTMPARAPVQVVVTACV -RGAGTAASERALRELGAALT--- ->[subseq from] Uncharacterized protein n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=A0A317CV13_9ACTN -------------------AGVTVRDLSGDQQV-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---DTGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DDA4A8A -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381P820_9ZZZZ -----EKKIISKFNDETGNFALAFKNLDDGKEI-LINENEIFHAASTMKTPVMIEFYKQLH -QGKLSLEDTLQIKNESIVDGTMYKYNKLGQYYSINNLIYEMITISSNFATNILIDYI-GA -NNVTKSMKEIGALNIDILRGVEDIKA-FELGLNNTTSAKDLLIIYEKLAKGKIINNESSA -IMIDILKDQKY-DDIIPKYLPKDIEIANKTGMIT-GVHHDSGIVFLKDGKKYVIIILSKN -MS-DMESGTEMMAKISELIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodothermaeota bacterium MED-G18 TaxID=1986239 RepID=A0A2A5X8V1_9BACT ----LENKISNLIKSHKGTFAVALKSLDDGNTI-LINENEIFHAASTMKTPVMIELFKKKH -NGEISFEDSLQIKNESIVDGSKFVYKKLGKYISIRELVSAMITKSSNFSTNLLIDYI-NV -KNVNKTMRDMGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGSFINPSISN -EMVEILKNQVY-NDIIPKYLPDNVEVAHKTGWIS-GVRHDSGIVFLENGKKYILILLSKN -LDD-DIEGAEFLAKISLEIFN-- ->[subseq from] Serine hydrolase n=1 Tax=Flavobacteriaceae bacterium 10Alg115 TaxID=2584122 RepID=A0A5B7U0I7_9FLAO --eNLESTILSQIDSIDGTVAVAFFNLSAPEDSlFINIDEKFHAASTMKVPVMIELFKQAA -QGKFNLNDSVFLKNESIVDSSLYSYNKINKKVAIKDLMYSMITASSNLATNVLIELV-DA -KKVTATMRDLGAKDIEVLRGVEDLKA-FEKGLSNSTTARDLMIIMKAIAQHKAGSEADSK -AMIAVLEDQLF-KSIIPKYLPKTLKVAHKTGSIT-GVHHDAGIVYLPDGKSYVLVILSKN -IKNS-DTATQQLARISKTIYDY- ->[subseq from] NLP/P60 protein n=1 Tax=Alkaliphilus metalliredigens (strain QYMF) TaxID=293826 RepID=A6TPV9_ALKMQ ----LKEQILEVLMETEAQVSVSIKDMSRNQWViRLNDTHKMPSASIIKLLIMIEAFCQVE -EKKFQLNQSLTIPKQDQIPHSMTTDL-EENTFQFVDLVQLMITVSDNTATNVLIDLL-GF -ENINQRAEKLGLKETVLSRKMLDFKAA-KEGRQNLTHGEDAIRMMELIVTEQAASPPMCR -RMMDILFNQQD-REMLRRFIPKKVKVAHKTGDLPN-LNHDVGWVLLSDM-SYLIGVFVNG -AA-DNLEAKTIIGKISKLAYDYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7YXG8_9BACT -----------------ENLGIAFYDAQTTIQW-AYNGDQYFHAASTMKLAVLLGVFRQVE -RGELSLEAAVHIRNRSIVNQQPFMYGHLGRTLTIRELAYWMITKSSNLATNLLVEVV-GV -PTIQHALDELEIDGVRILRGVEDQ-AAFEAGLNNEVTANGLLKMLRLIADGRAYSKVASD -EMLNIMLEQQY-RSGIPAGLPKAARVAHKTGNIST-VHHDAGIVFVEDRKPYVLVILTQF -PAES--ARGTAVADVSRDIYN-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=UPI0002D1BCFE ---ELNEKIKEIINESGTDIGILVKDLTNDKVIiNYNENKSYVSASLIKIPIFIEALRRVD -NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL -DNINNIVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR -RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN -VNN-NLEGCKIIGSISKVIYEYf ->[subseq from] serine hydrolase n=1 Tax=Millionella massiliensis TaxID=1871023 RepID=UPI0009F37F9E ----LRKKLETAISDVPGRVGIAVIS-PEGDTL-TVNNGGDYQLMSVFKLHQALAVAHALD -LQGVSLDTVIRVRRTEFDPWSPVLTEKSDSLLTVTEWLSYLLQQSDNNVSNMLFQRIASV -AATDSFIRATGITDFRLTVMEEQMHRDHSLADGNRSTPLACASLIRKVFNDSLVSPAKQE -AIRRILSECRTGLDRIHVPLAPSVTLAHKTGSGFRTAHNDVGYVTLPDGRAYALAVLVKD -FDGSEAEASAVIAKVSEIVYEAy ->[subseq from] Beta-lactamase n=2 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174L833_9CLOT ---SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE -EGTLNPDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE -KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETSLWLY--- ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus chungangensis TaxID=1229152 RepID=A0A3D8PWP7_9BACI --eQLSQSIERIIEQAGGKWGISIEELDTNNSW-SLNEEELFYAVSIIKIPIMIAVFTAYE -KEKLYLSDTLELKVEEMVGGSGVLQHLSPGILTINDLITLMIIQSDNTATNMLINLI-EK -KNIQQTMKDIGMQKSKFYNKLMTVPATLQG--YNEITAQEVTMMLKKIATGKIISRHACE -RMLAIMKKQQL-TDCLPAKLRPEWQLANKTGFVS-GMRHDIGIFYVGDR-VMVTTVLSKG -LD--DNHSKDAIAKVGLEIYHY- ->[subseq from] serine hydrolase n=1 Tax=Lentibacillus sediminis TaxID=1940529 RepID=UPI000C1C4E84 --qKLIEKVQSTIQATGGEWGIVLEDLNTGEKW-EHHADNLFYAASVIKLPIMAAVFAESE -KGNIDIHGTLSLRKEDMVGGSGVLQHMTQNPLAIYDLMMLMIIQSDNTATNVLIDLV-GV -DNIQKTMQEIGMEKSSFYHKMMIGDRK----VKNELTSRDVGVFLKKLHKGGVVSAEASN -QMIDIMKRQQI-RDCLAGDLPARWELANKTGWVP-GVRHDVGIFSVGDE-CIAVSVLSCG -AD--DLESRRGLAEIGESVY--- ->[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus stilesii TaxID=331679 RepID=A0A5R9BVA4_9LACO ---KVEGTIEDAFGDISGTTSVYVSPTDSSEKVvSHNGAQR--AASNIKLFIMVTAYNAIS -EGQLNLDDEYTLKDSDKVDGTGAIRETAGTKLTIQRLIDYMMEDSDNTAANIMIRELGGM -DAVNKQIKKMGATDTKLERMLMDTD-ALKSGKDNYTSVTDLGETLKKIYNHQMISTKYDN -AMLDVLKQNKN-RTKLPHDLPDEATVYNKTGEFDYGVENDAAIFGNTKG-SFVIVVMSED -GQRNEQ----------------- ->[subseq from] Serine hydrolase n=2 Tax=Clostridium TaxID=1485 RepID=A0A3M0SNK3_9CLOT -------KILNAIDLKKLNCAFVIENLKTGEKI-AYNENVVVSSASLIKIPIMMEILNQVK -EGKLSLKQRITVEDDVKVPFSILNLLESGNSYTLKDVITLMIIQSDNTAANILMDLA-GM -DNVNNYIKDLEIKNTVLQRKMLDSKAR-KEGRENKTTAADMAKFFEIIYKGEKAKEFYSV -IMKNILTSQLD-NSVMRLNIPDDIRIAHKTGDLN-GISHDAGIVYLPNVD-YIFCGLTWD -AV-TNNFARETIGKISKIAYDYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus novalis TaxID=220687 RepID=UPI000826BB9B ----LEEKIKGEITCFQGRIGIAVEI--ANKRI-SLNSVEVFPSASVIKVPILIEGLRQAE -TGKINLNELTTIDK--RVGGSGVLQALSAKVMTIKDLMTLMITVSDNTTTNLLIDLL-GM -DSINSTIEKLSMEHTKLSRKMMDFE-AIEQGYNNFTSPSDMIKCLKVINEGDFLSEESRK -LAVEIMHYQQF-HDKLTAMMDDRVFAASKTGGLPN-VEHDCAILKYGGKT--AYAVVLTD -QLDNHFAAKQLISKIGKHLYDH- ->[subseq from] serine hydrolase n=1 Tax=Paludisphaera sp. JC670 TaxID=2712865 RepID=UPI0013EB3C10 ---DLAGRIEALAKAHKGKAAVAFKNLQTGESY-ALDADAPMPTASLVKFPVMIEAYRQAA -EGKVDLDSPVMLTKKDKVPGSGVLTSHFSEGFPLLDAVHLMITYSDNTATNLVLDAI-GI -GSTAATMEALGCPNTKIHSKVYRRDTRSKVYGLGSTTAAEMIRLFEALHARKLVDEKASE -AMWKHLLTCDD-RAKFPRFLPPGTKVAFKTGSVD-ASRTCAGVIETKGG-PVALCVLTDE -NESDDNAGNLLCAKIAREVYDHf ->[subseq from] Serine hydrolase n=1 Tax=Gelidibacter gilvus TaxID=59602 RepID=A0A4Q0XFZ4_9FLAO --eTLEKTIQAQIDSIDGTVAVAFYSLYQPKDSlLINVDEKFHAASTMKVPVMIELFKQAS -EGKLNLKDSILLKNESIVDGSLYSYSQIGTKVAISDLMHSMITVSSNLATNILIELV-DA -QKVTATMRSLGAKNIDVLRGVEDQK-AYDKGLSNATTAKDLMIIMEAIATHTAGKQQDCD -AMITILKDQQH-KDVIPVYLPKEVEVAHKTGSIT-GVHHDAGIIYLPNGRAYILVLLSKN -LK-DFDKGTDQLAKLSKTVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=A0A271J0B9_9BACT ------------LARHAATVAVVVRRAAPGDTV-AYNADRPFHAASTMKVPVMIEAFRQVE -TGLRAWDDPVRVENRSIVDGSEFAYSRLGQDVPFRDLVERAITTSSNLATNLLIDRL-TA -DSVQATAVRLGAPGMRVLRGVEDLKA-FEAGLNNRTTAGALATLMEALRDGRAVSPEADA -AMVDVLDDQAF-NEMIPADLPAGVRVAHKTGEITE-IHHDAAIVYPEGAAPYVLVILTEG -LE-DHAESARLGAEVSRAIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3D2Y6V7_PSESP ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0005EB135E ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGAMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000922A6EB ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=UPI00082CAFA9 ---------------EKVQGAFLIKDLSDGETF-CYNEYLKVPSASLIKMYILVEAFRRIK -GGLLTLDEEIAVQKEDLVDFSVL-QFLRPRIYSLEELLRLMVVYSDNTATNVLVDYF-SM -SSLNELMQQIGCKTSVIQRKMMDFAAA-EEGRQNYTSVIDMASLLERLYQGKLLGQPFDA -QMLDIMKGQAD-EEAMRRDLPDELIIARKSGELD-ALDHDIAIVYAEKRN-YIYVFFSWE --TGDNNRGRKVLAETSRLVFDYf ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DD636EF -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPQGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---STGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VA21_9BACT --dRLRERIEAIDRTLDGVCGVAVRDHRTGATI-ELRADELFPAASTIKLAILYELFRQAE -EGRVDLAE-VTRPPLPRVGGGGILQRLGGRVLTWRDLSVLMIGWSDNEAANLLAGKV-GM -DAVNRRLDTLGLARTRLRRRMMDLAAA-REGRENVSTPAELARLAEAVAYGTGLPAELAR -DLRAVAATPES-HTAFRAALPEPLVAYTKSGELE-AVRCEVGYVDLPGR-PYTAAVMTTY -LRRD-ADGEAAIRDVSAAVYDTf ->[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus arsenicus TaxID=255247 RepID=A0A1V3G5G4_9BACI --kQIENDLLRLISSGKGTYGISIYYFETEEEF-VYNHDEEFYAASIIKIPIMSAVLAQVS -EGKRSLSDKIRVRSEDMVSGDGILKNLTPGTWTIHDLVVLMIIESDNTATNLLIDIL-GV -ENIQLYMTIWGFKQTQFRHKLQ-IKPSRKHNESNLITAKEMNHFLRDIAMGNIVSMSVCR -KMIEIMKQQKM-NDLLPSLLPENWEMAHKTGYVP-GVEHNVGLFYLPGHT-FAISALSKN -VP-NRDEPKRIMSELGSLLF--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. M05W1-28 TaxID=2420510 RepID=A0A420VUR6_9SPHI --rKLEQQIKQLIHGFQGEVGVYVHDLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE -KGQLQLDQELVYRESQKYGGSGLMQFFKDSSVDLKTLIALMLSYSDNVTSIWNQKLAGGG -IAINTLMADLQLRHTRVNSQTEGRKTDWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD -RMYRFLGNMFY-DERGLSQIPSTVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN -NQGKTNAAEVLTRKLSKLLWDYy ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0013302D75 ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A6A4XJB7_PEDAC ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Uncharacterized protein n=2 Tax=Halomonas sp. KO116 TaxID=1504981 RepID=A0A0D5LZM1_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- --RAQALARALGVSTFFTQPDYDHAFDAYEATGENVGTLRAFGDLLASLHGGMDLSAEQRQ -TLLAVMQRTSSGKRRLKAGLGSGVSFAHKTGTQQR-RSCDAGIAKRDTEGPWVIVSCARG -PV-AVSAHERALASVGEA----- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000BEF0549 ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000466DCE7 ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Beta-lactamase domain-containing protein (Fragment) n=2 Tax=marine sediment metagenome TaxID=412755 RepID=X1IKI5_9ZZZZ ------------------------------------------------------------- ----------------------------------------------------------GGP -KELTAFLHNMGDHVTRLDRWEPELNEVIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] hypothetical protein n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=UPI0012F7BD4E -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVALDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=UPI0011B436B0 -------------------AGVTVRDLSGDQQV-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---DTGDETVRRMARTVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E7U145_9BACT ---DLASRIEANLDALNAKTSFYAKHLPSGREI-AIRADEPMNALSVIKIPIMVLAYRDAD -AGALDLDERYQVQPEDMRRGSGLLQSFTPGIPTYRDIITQMIITSDNTATDVMINRL-GL -ERVNTMLTELGFEQTRLRATTGELFKGDSTQWLGRITAREISQMLEAIEEGEFASPESSD -EMIGILRRQFY-RSMLPQRLRDRASIAHKTGGWPPDAANDVGILYYEGG-PIVVAVFTNQ -NKGNFFELEATVGRIAADLVDHw ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus thermotolerans TaxID=338644 RepID=A0A3S6Z786_9FIRM --------LREWIGTLPGIYGVFAKNLDTGKVF-TFNDTKVFPSASTIKVPILIELYRRVE -EEHLSLDHLLVMRREDQVGGSGVLKDLSPNTYSLRDLATLMITVSDNTATNLLIDFL-TI -EAVNITLRRLGVTHTELVRRLQRVPA-EPLDTVNHTTAQNMGLLMEKLARGTAISLAASE -QMVSLLKRCQG-PISITKLTAESIVIAHKTGSLAQ-ASHDVGIVYSPHLR-YVAALLSQG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Laceyella sacchari TaxID=37482 RepID=A0A2I7SSU4_LACSH ---RLIQNLEHWKSRAVGNWGVWIEDLTSATTW-AWNETKSFYAASIIKVPIMVAVYKQAF -LGRLALADEIILTAEDQVGGTGVLQHLSPGLFSVQDLTTLMIIQSDNTATNILIDLL-GT -ETIRETMDELGMRQSTFHNKLMIVPAAPAG--LNMITAADVARCFRHIAQGKVVSQHASR -QMVEILKKQQL-RDCLPTGLPSQWELAHKTGMVTR-TLHDAGILFTKSRA-VVMVALSEE -CE--YEQAQQQMKQLARLVYE-- ->[subseq from] serine hydrolase n=1 Tax=Roseimicrobium sp. ORNL1 TaxID=2711231 RepID=UPI0013E14269 -----------------VRASVAAYDHETGRTF-GWHEQEWFHAASTMKVAVLLAVFRAVD -EKRLRLDDPLHVRNRFISAGEPFRHQRIGRTMRIRELAHRMITVSSNLATNLLLDLI-GL -EYAQRVLHDAGVTGIHLKRGVEDAA-AHEMGINNEVTSAGLVSLFRVIQEGQFTTAKSRE -AMLQILFDQKY-NAVLPKKLPPGTRVAHKTGEIST-VSHDAGLFFVKERPPYAFAILTEV -LPES-NGRTATVAAMSEAVCDYf ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=UPI0011A2DA93 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTVRRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILAPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 3-3 TaxID=2070757 RepID=UPI000CDA4F52 ---ELNEKIKEIINESGTDIGILVKDLTNDKVIvNYNENKSYISASLIKIPIFIEALRRVD -NMEIPLSKEFEIDKIQKVEYSVITEQDLDI-CTYEELMEWMIISSDNSATNVLIDIL-GL -DNINNTVDKFSMNSTKLQRKMMDFK-AIDEGKNNYTSLNDMLLLMEGLYRGNIEEKEICR -RALETLKNQRD-NSMLKRYIKDNVVLANKTGELDN-LNNDVGIFYTKNID-YFIGVFAQN -VNN-NLEGCKIIGSISKVIYEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Pediococcus stilesii TaxID=331679 RepID=A0A0R2KXT6_9LACO ---KVEGTIEDAFGDISGTTSVYVSPTDSSEKVvSHNGAQR--AASNIKLFIMITAYNAIS -EGQLNLDDEYTLKDSDKVDGTGAIRETAGTKLTIQRLIDYMMEDSDNTAANIMIRELGGM -DAVNKQIKKMGATDTKLERMLMDTD-ALKSGKDNYTSVTDLGETLKKIYNHQMISTKYDN -AMLDVLKQNKN-RTKLPHDLPNEATVYNKTGEFDYGVENDAAIFGNTKG-SFVIVVMSED -GQRNEQ----------------- ->[subseq from] Serine hydrolase n=1 Tax=Blastopirellula marina TaxID=124 RepID=A0A2S8FR35_9BACT ---ELRNLLMPLIEKHRGDVGVVIKHVPSGEMF-SYQADQPMSTASLIKLPLLMATYEKVH -AGDTSLDSMITLEESDKVPGSGILTKHFSPGLSLRDAIQLMVAYSDNTATNLVIDEV-GL -DTTNALMKKLECGETRLNSKVFRRDTRSKAFGLGSTSANDMLVMLTALHDRSFVDKATSD -QIMKHLYDCED-RMKAARYLPASVKVAHKGGSVN-AARTDAGIIDLPEGGSILFCILTMN -NKTDENEGDVLSADIGKSVYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium siyangense TaxID=459529 RepID=A0A562MGU0_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQNLAGGG -VAINKLMSELQLTQTRVNSQTEGRKSDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD -QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEVLTRKLSKLLWDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudobacter ginsenosidimutans TaxID=661488 RepID=A0A4Q7N6A6_9BACT -----------FASHPEGYFAIAFKDLSSGKTF-FMNEHASFHAASTMKTPVLIETFRQAS -KKRFKIEDPIEIKNSSIVDGSPYSYTHIGQKLPISDVLHRMITKSSNLATNIMIDLV-DA -KKVMATMRSLGAKDIQVLRGVEDDK-AFEKGLNNTTTAFDLMLIMEHLANGTAVNKKASE -AMIKILMDQYF-RDVIPAKLPADVKVASKSGSIT-GICHDSGIVFLPDGRKYIIVLLSKG -IK-DHKEATNTLANASRIIYDHy ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. WF146 TaxID=319501 RepID=A0A1A5WUU4_9BACL -------SIGKLMEETGGQWGIYLEDVRTGERL-GFAEHQRFYAASLIKVPIMTAVFAEAY -AGRLALSDKLRLRREDQVGGDGVLQHLTPGTLTVYDAVTLMIIQSDNTATNMLIDLV-GT -DAIRAAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRCLATGKAISYNSCL -HMINILKRQQH-RDRIPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VIICALSKN -VD--AKAAGEMMGQIGRMVYDLy ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI00132F8381 ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEDMMEDSDNTAANIVIRQLGGM -NKVNAQIKKIGAKDTKLERMLMDMD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDE-QIK-------------- ->[subseq from] Serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A1L6H7Z3_PEDAC ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FIIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroidetes bacterium OLB12 TaxID=1619897 RepID=A0A136LLA7_9BACT ---ETIQQIQEILSKPTGTFALAYKDLITGDEI-LINEHELFHAASTMKTPVMVEVYRQAA -AGKFSLKDSILIKNESILDGSPYSYDHIGEKRTVYSLMHDMIIISSNLATNLIVELV-DA -KNVNQTMRAMGANDIQILRGVEDTK-AYEAGMNNQVTAYDLMLLFEKIDKEEIVNEEASM -AMMDILLDQKF-NDIIPAKLPANVKVAHKTGFIT-GVHHDSGIVFLPDGKKYVLVLLSKG -LK-DETAGIEAMANVSELLYHY- ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SD09_9BACT ------------------------------------------------------------- --------------------------------LSFSEIIKSTVSHSDNNGCDILFRFVGGT -NKVHNFISKLGVKNISIKATEEEMHKAWNVQYTDWTTPDATVQLLKKFYKNEILSKNSYD -FLLNTMIETTTGPKRLKGLLPDGTVVAHKTGSSDTAATNDIGIITLPNGKHFAIAVYVSD -SSEKSDVNEKIIAEICKSVWDY- ->[subseq from] Uncharacterized protein n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=A0A172YJ61_9GAMM ------------------------------------------------------------- -------------------------------------------------------AAI-GP -RRVDAVARALGVERAELEDDIDAAYADYYAQGDNSAALADVARLFEGLVEGELLNSEHRA -LLYRLMKIDRYEAYRLEGGLDETTEFIHKTGTQRE-RACHAGVIDPSDPERAIVVIACTQ -DMDEASPSETLLEQVGASI---- ->[subseq from] serine hydrolase n=1 Tax=Saccharospirillum mangrovi TaxID=2161747 RepID=UPI000D39A9B3 ---SLNARLLQIDADFPGELGVYVKDLRTGESV-GLREMEPWYLASTVKIAVAITLLEAVD -AGQLTLDQRVELQPLDYVDGAGDTNRLTPGTVSVRYLFEQMLIHSDNTATDVLLRLL-GT -DAVNQVARSVGFGVGRI------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Muricauda olearia TaxID=552546 RepID=A0A444VPM2_9FLAO ----LEDKVHAQIDSIEGNVAVAFLNLSDPSDTlYINENEEFHAASTMKVPVMIELFKQKE -EGKINLNDSILLINESIVDGSSYSYNKINTQVALKDLMYNMITVSGNLATNVLIELV-DA -KKVTATMRDLGAENIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCN -DMIAILKDQRF-NDLIPRDLPKNVEVAHKTGWIT-GVHHDAGIVYLPDGQSYVLVLLSKN -IQ-DSDKGTQQLADISKAFYDY- ->[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. URHA0033 TaxID=1298862 RepID=UPI0004837947 --qKMTADFQPIADRVPGQLGVAVEDLGTGQII-SFNGERRFPLQGAALIPLGAAVMAEVE -AGRLRLDDVVLIEDVDLSPPSAIADAWPGRNYTVEELLERAVGQGDATAADVLLKRVGGP -GAVTAWLQGRRVNNLDLDRYQRQLLPAALADPRDTATPLGVVRLLEALNQAELLGPESRR -RLGRIIGQTREGPGRLRAALPDGAHLVHLPATARTDMVGDVGVYTLKDGRKFAVIAFVSG -SPLPVAAQEQAIADVGRVVIK-- ->[subseq from] Beta-lactamase PSE-4 n=1 Tax=Clostridium felsineum DSM 794 TaxID=1121310 RepID=A0A1S8LAV5_9CLOT ---ALDNAIKNILALRCEDISLVFLDLNNTSNYiYINENKIFPSASTIKVLILAEALNEVL -NGKLSLDAPIEVKTSDKVPYSILTS-LTNNKYPLIDLLTLMIISSDNTASNILIDLL-TM -DSINNYGQSIGLKNTSLKRKMMDSKA-VQRGMDNLTSAFDMLTLFKKIYNHELLNPKMCN -LILKILGANTD-QEVLLRYLEADIRCAHKTGDLSN-LNHDIGVFKTKTS-EYILGVFVRN -ADFN-YVAKDLIGKVSKIVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A427GMV8_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVTCAE -GLDEGKEAGSLFEQVGEAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Arsenicibacter rosenii TaxID=1750698 RepID=A0A1S2VK58_9BACT ----------------SVTVSLAVQSLADQTSF-YHQADDRSPSASIIKLPVMVEAMEQVK -AGTFALTEKHLLTEAEKAGGSGVLQTYAAGSVTNLELVTLMITHSDNTATNILIHKL-GK -DAINRRIKALGLPQTQLNRIMMDTAA-VRRGIENYVTAREMNTLLTAIYRQTIATPALCT -QMLGILKQNTD-TLTIPRLIPETVAIAHKTGTLTY-VRGDAGIVYA--RRPFVMSVLVRG -TT--TEKAEQIIGDLALHCFTYf ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoflexibacter ruber TaxID=1003 RepID=A0A1I2JAG5_9BACT --nDLKKQIQAKFASIKGEFALAYKDLDNPSDTlFINAFTDFHAASTMKTAVMLEVFKQAQ -EGKFALTDSLTLKNESIVDSSAYSYSSLGQKRTIYQLVYEMITVSSNLATNMLIEIV-GA -ENVTQTLHSLGINQMKVLRGVEDSKA-FGKGMNNTVTAYDLALLLEKIAMNQVLNVKACE -EMRKILLNQKF-NDVIPALLPQEVKVAHKTGTIT-GVHHDSAIVYLPNGKKYVLVLLSRK -ME-DFDKGTKMLSEVSKLIYEY- ->[subseq from] Beta-lactamase n=1 Tax=Halomonas sp. HAL1 TaxID=550984 RepID=G4FB08_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- --RAQALARALGVSTESFTQDYDHAFDAYEATGENVGTLRAFGDLLASLHGGTDLSAEQRQ -TLLAVMQRTSSGKRRLKAGLGEGINFAHKTGTQQR-RSCDAGIAERATEGPWVIVSCARG -PVA-VNAHERALASVGEA----- ->[subseq from] serine hydrolase n=1 Tax=Muricauda olearia TaxID=552546 RepID=UPI00101CF502 ----LEDKVHAQIDSIEGNVAVAFLNLSDPSDTlYINENEEFHAASTMKVPVMIELFKQKE -EGKINLNDSILLINESIVDGSSYSYNKINTQVALKDLMYNMITVSGNLATNVLIELV-DA -KKVTATMRDLGAENIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMEAIATNKAGTKEDCN -DMIAILKDQRF-NDLIPRDLPKNVEVAHKTGWIT-GVHHDAGIVYLPDGQSYVLVLLSKN -IQ-DSDKGTQQLADISKAFYDY- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q7DNX2_9BACT -----RERLAARIARAASGVGVYYKRLTRPDSL-LLGANLRFHAASTMKVPVMIQIFRDAD -EGLLRLDDSLAVRAASLVDGSPFDYQRVGGTASIRELLDLMITRSSNLATNLLIDRV-GA -PRAQASARLLGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGALLAAIAQNRAASPSSCE -EMLRILGRQEF-NEGIPVGVPPGTRVAHKTGWIGGVVYHDAALVYPPSG-SYVLVVLTGG -IKED-SVAHNLVADLSRMVYA-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-22090 TaxID=1581038 RepID=UPI00119FBE05 ---ELISKVQKLIKPSKGTWGIVLEDLNTGDKW-EYNEQELFYAASVIKVPIMVAVFRAVE -RLELSLSDLIILDKDEYVGGSGVLQHLTPGTLPLSDIILLMIIQSDNTATNLLIDLV-GV -ENIKQTMKEAGMEHSTFYNKLMLSKPN--PHGTNRIAAKDVGILLTKIAQGEIVSEQASK -QMIEIMKKQQM-RDCLPEKLPPAWEFANKGGWIP-GTRHDVGIFFVGDRK-LVATVLSEK -ED--DVLAKRILSQIGYEIYQY- ->[subseq from] serine hydrolase n=1 Tax=Thermoactinomyces vulgaris TaxID=2026 RepID=UPI0011077722 --qKLSGSLDAWKKKSSGIWGIWMEDLNTGEKW-IWNEKQPFVAASMIKVPVMVAVYRAHA -LGKLCLSDRIELRREDRVGGSGVLQHLSYGTFTIQDLVTLMIIQSDNTATNLLIDRL-GK -EFVQETLLALEMTDTVFINRLHIVPAG--SNITNQITAKDMARCFRLLATGQAVSRDASR -KMVEILKKQQW-RNCLPGRLPPSWEMAHKTGWVNQ-TLHDGGILYIASH-SLILVVLSSG -LDH--HQAQREINHIGKWVYDAy ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F846B45 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Uncharacterized protein n=1 Tax=Tumebacillus flagellatus TaxID=1157490 RepID=A0A074LXM4_9BACL --------LQKRLDAASGTFGASIYHFQSQERF-DSNADEVFFAASIIKVPVMAAVFDLAA -KGKLSLSETMALRTEDKTTGSGILFNLSTGLLSLRDLVVLMIIESDNSATNMLIDRV-GM -ETVQACMAEWGMEQTRIYNKLAVIPAN--LQNVNTITPRELTDFMIKLANGKIVSWKASR -EMIDILKQQKF-NDAIPSLLPPTYEMAHKTGWVSN-VENDTGLLYFPGHT-FAISIFTKD -VT-DKPATKRVMGEIGLDL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus ratkowskyi TaxID=57028 RepID=A0A2W7RGK9_9BACT ----LQTTIQSQIDSIQGNVAVAFYNLSDSDSL-QINADEEFHAASTMKVPVMIELYKHQA -QGKLNLSDTIFLKNESIVDSSLYSYGKIGSVVTLNDLLYPMITVSSNLATNVLIELV-GA -RNVTATMRDLGAEKIQVLRGVEDQK-AFDLGLSNSTTAKDLMMIMKAIAENTAGTEADCK -EMIAIMKDQQF-KEIIPFYLPKEVTVAHKTGSIT-GVHHDAGIIYLPDGRSYVLVLLSKN -LE-DFVVGTEQLAGISKSVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_4_65_8 TaxID=1803456 RepID=A0A1Q7JX14_9BACT --qRLQASIERTTRSISAAWGVYVKSLETGEEI-ALDADRQMETMSTIKIPLMVEAFEQIK -AGTFKLTDKYTFAQADSQPGTGTIQRLDPGAMTVKDLLTMMIIVSDNTATEVLYRMVGGP -DAVTRRMDALGLTKTRAMNIPSKWFARDGKNPFGLSTPREMGRLLEMMERGTLVDKASSE -LMLQMMRGQLY-RTRIPRYVT-GYRIPHKTGDFLPYVGDDVGMLEAQGK-TIIVSIFTGN -HFGSGEALENAIGLVAKDVADYf ->[subseq from] serine hydrolase n=1 Tax=Peptoniphilus grossensis TaxID=1465756 RepID=UPI0003031F03 --dNLKNDIENLIKESSASISVTFCDLDNDEKF-SINGNKKVPSASMIKLLIMLTLLKKVE -LKEISLDEKTKLVEDKRVGGSGVLKDLSCDHFTIKELLTLMIIISDNYATNILIEKI-GM -DNINKLGKELNLLETSLERIMMDTDAQ-SRGLDNFTSSEDVFSVLKIIYEKSFLREDLSE -LALDILLRQQE-RDRLQRYLPEDLKIANKSGDLDF-LENDGGIFFTNSK-NYILVVLVNN -AD-SNVIAKDIIGKISLKIYN-- ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium AD-493-K16_JPT_193m TaxID=2587841 RepID=A0A5N8YYK5_9CHLR ---RLESRLSHMIDGFAGVAGASVKDLSSGDGV-SVRGDEQFPTASTIKIHVLTQLLSRAE -RGELDLGKRIRLTPEMFGAGSGVIHYMENEPLSLLDIATLMIIVSDNTATNMCIDLA-GI -EGTNELLNKMGLKATKLRRKMMDSD-AIQRGDENVSTPNDLVEMLTLLHSGKP-SSKVAD -QVLHIIGKPKS--APINRGVPSGLVVANKPGGMER-VRCDAGIVFLDKN-PYALSIMTNF -GLEDGVKQEAFIVEVVKEI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A3S5EAG8_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=UPI000F0A593C ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANSLELKTDQLESDLDEAYRRYYQTGLNSATLVAYGQLLGKLASGELLSPESTE -LLYGIMGLDKYEAYRLEAGLDKALPFIQKTGTQQY-RACHVGVANPQDENALVIVACAAE -LDEN-DEAGKLFEQVGEAV---- ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sulfidaeris TaxID=115553 RepID=A0A365TQ60_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLRAFGDLLASLHGGDDLSAEQRQ -TLLAVMQGTRSGKRRLKAGLGSGVSFAHKTGTQQR-RSCDAGIAERANEGPWVIVSCARG -PVA-VSAHERALAKVGEA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. OV322 TaxID=1882764 RepID=A0A1I1FM60_9BACI ---NLQKKIELHIAEFPGRISYKIES--EDQSI-QKDAGEGFQAASLIKIPIIMEGFRQIE -EGKIHLNERAEISDSDLAGGSGVLQALSKSGFTIEDMLTLMIIVSDNTATNMLIRKM-GI -NIINQTIASLNLKKTILGRYMMDFD-AIENGFDNYTCADDMVTCLRSIHQGSFLSGESRQ -HILSIMEKQQL-ISKLPAMMNNKVKVASKNGAIP-GAEHDSAIITRGDV--TVFAAVLTD -SLENEEDGRRIISQIGRYIYEE- ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter flavus TaxID=287099 RepID=A0A1I5CKS3_9FLAO --qNLKQQIDSVFAETQGDFAIAFKELSEEKRTiLIDEHENFHAASTMKTPVMIEVFKQAE -AGRFSLDDSLLVKNESILDDSSFSYSLIGKKRSIKDLVVDMISQSSNLATNIIIELV-DA -KNVNKSMRELGAKNINVIRGVEDMK-AYEAGLSNSTTAYDLMLIFEALANGEAVNPESDK -EMLDILRLQQH-TDLIPALLPKDVKIANKTGWIT-GVHHDSALVELPDGRSYVLILLSRN -MK-DMEAGTQMLAGISKKIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus caseinilyticus TaxID=1503961 RepID=UPI00111377F8 ----------------------AIKHVESGQEV-IINGEKQFEMASVFKLPVLVALLTNAA -PRAVSLDTRMEIRQNDRVPGSGIIKELDEGLMTIRDLATLMIIVSDNTAADMVLHMI-GK -ENVNRKMKELGLENIVVRQSCWELLTMENTRQGNRATVTDTNALLEKIVTRRI-EVTASK -QIIDILSRQQY-RQRLPSLLPPATKTANKTGTIGT-VVNDAGILFLPDHKGTLIITVFSE -GNRTLAAGENVIAKIAKTAFDHy ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI00071AF38C ----VEGTIRDAFGDISGDNAVYVSPVDSDTEV-DFN-DQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q6ZMN3_9BACT ---TLQTRVEARIAKTPARVGVYYRDLADRDSL-TVGAAARFHAASTMKLPVMIQLFRDRD -AGRLSLDDSLTVTNTSIVDSSPYQYKRLGQRVSIRDLIELMETVSSNLATNLLIAKV-GA -QRANATAHLLGADSILVLRGVEDGK-AYRAGLNNTTTARDLGILLAAIANVRAASGGSCR -DMLDILGRQQF-NEGIPAGLPPGTRVHHKTGWIEKVVYHDAALVQPPGDRGYVLVVLTAG -IQKN-DDAYALVRDLSRIVYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9X069_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PIC25 TaxID=1958773 RepID=A0A2A2DP10_9PSED ------------------------------------------------------------- ------------------------------------------------------------- -----TLARQLGVAPTQLRPSLGEAFEAYYATRLNSARLSAYGELLEALVNGKALGAEGSA -HLLGLMERVATGRKRIKAGLPTVAAFLHKTGTQRS-RFCDLGIVRTAGGDKRLIVAACTR -GDSSLARSETALRLVGQAVWQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YMQ6_9BACL --sKLEKTIQELAASVDGRVAVYIEW--DEGRI-GLNEQEAFPSASLIKIPIMLEALRQEQ -VGQTDLNTSLAIPAEERVGGMGVLANLSSDILPLRDLVSLMIAISDNTATNLVIQKV-TM -EAVNQLAARLGCQQTVLARKMMDTEA-VRQGRDNYTSAQDIGLFLKEIIVGNALDSSRKE -AAFQMMRQQQF-HTKLPAELPLDACFAHKTGELA-GIEHDAGILKIGKQ-YITMAVLTRD -L-ADEAAGREFIAKVGKAVFDTf ->[subseq from] Serine hydrolase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NEQ5_9BACT ---SVAAHIGQLLLQHKGNFAVAFKDPASGKTL-FINEHALFHAASTMKTPVMMEVYQQAA -AGLLSMNDAVPVHNHSIADSSVYTYTKIGTNMRLYDLVYAMIIRSSNLATNIVIEKV-GA -PNVMRTMRHMGAQQIQVLRGVED-NKAFAAGLNNKVTAYDLMLLYEALANGRAVNAAAST -DMIDILLHQEF-NDIIPARLPAGVKVAHKTGNIT-GVHHDSGIVYLPDGRKYVLVLLSSG -WD-DEGDAIAAMAEVSRLLYS-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=UPI000F5FB9F7 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=A0A1G7S9B8_9PSED ----LLARLQNIAAKQDGELGVYVKDLHSNLAV-TLHAEELWYMASGIKVPVAITVLRGVE -RGDWNLDTRLTLAADDFVDGAGSTNQYGPGAVSVRALLEQMIIYSDNTATDRLIRLV-GI -DAVNELVGELVPEGFEPITSLADVRRRYYSSNLNAARLTAFGKLLERLAYGEALGAEQTD -YLLGVMSRVKTGSKRIIAGLPKDARYAHKTGTQR-ARICDSGLIETSGTAEPVLVVACVR -GELSLAKAERTLRQVGEAL---- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=UPI000BABC27A ---RLLEELSRIDTDYPGEIGVFAKDLDSGLSI-SFRGEETWYLASGIKVPVAIAVLRDVE -RGEFTLDDRLRLEAYDYVDGAGETNHHPPGALSVRFLLEQMVIHSDNSASDRLIRLV-GI -EAVNRVVEELAPGGFQPITPLADVRRAYYATQLNSARLSAYGELLEALANGKALGAEGSA -HLMGLMERVATGRKRIKAGLPTVAAFLHKTGTQR-ARFCDLGIVRTADGDKRLIVAACTR -GDSSLARSETALRLVGQAVWQ-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingomonadaceae bacterium PASS1 TaxID=2015579 RepID=A0A257DPU1_9SPHN --eKLRNDVDALWKKFPGRAGIAIYTPFSDDII-GRRQTERFPQQSVSKLWVALAILEQEA -AGKLSLDKQVRVSRDDVVVSQPIKRYLSGKDMPVSELLAHAINASDNLANSVLLRVAGGP -QAINQMLDRRKVQSIRFGPGEVLLQSSYLASPLDGAAPGTIVLALKRF--GERGPNDPGA -KLLKLMAGTYTGKSRLRSGLAPGWSLAHKTGTGQSTAVNDVGVMKAPDGCRYQVAVMIAE -TRAGKDVTNGLMQNVARAVVRH- ->[subseq from] Class A beta-lactamase n=1 Tax=Paenibacillus sp. FSL R5-0490 TaxID=1920424 RepID=A0A1R1ENV1_9BACL --hTLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAVFSSASLIKVPILLAGLSQAE -KGLLQLEEEVEVTASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI -EKINQLFKSLGFDHTSLNRKMMDFE-ALKNGIDNTTTARDMAYGLKALAEQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVMVANKTGELP-GIEHDCAIFTHKGK-TVCAAVLVDR -LQN-QAAGKEVLSAIGSRI---- ->[subseq from] serine hydrolase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=UPI00069360A0 ------------------------------------------------------------- -------------------------------------------------------AAI-GP -LRVDAVARALGVERAELEDDIDAAYADYYAQGDNSAALADVARLFEGLVEGELLNSEHRA -LLYRLMKIDRYEAYRLEGGLDEATEFIHKTGTQRQ-RACHAGVIDPSDPERAIVVIACTQ -DMDEASPSEALLERVGASI---- ->[subseq from] Peptidase_M14 domain-containing protein n=1 Tax=bacterium TaxID=1869227 RepID=A0A2W4U106_9BACT ---------ARIAQEAPAEVAVALVDLATGLRL-GIGDTVTMHAASTMKVPVLLELIRQVE -AGRLSLDARIPVVNESIADGSTYAYDAVGQERPIRELARRMIVRSSNLATNNLISYV-TP -DSIARTLARLGAPGMRVLRGVEDGP-AYARGMNNTTTAAAFARVLEAIARCEEVSRAGCE -EMIDILAAQEF-NEMIPAGLPPGTRVAHKTGWITR-IHHDGGIVFPPGREPYVLVVLTRG -FD-DKERSARVGADISRAVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Psychrobacillus sp. AK 1817 TaxID=2303505 RepID=A0A5J6PM77_9BACI ---ELISKVQKLIKPSKGTWGIVLEDLNSGDKW-EYNEQELFYAASVIKVPIMVAVFRAVE -RLELSLSDWIILDKDECVGGSGVLQHLTPGTLSLSDIMLLMIIQSDNTATNLLIDLV-GV -ENIQQTMKEAGMEHSTFYNKLMLSKPN--PHGTNRIAAKDVGILLTKMAQGEIVSEQASK -QMIEIMKKQQM-RDCLPEKLPPAWELANKGGWIP-GTRHDVGIFFVGDRK-LVATVLSEK -ED--DVLAKRILSQIGYEIYQY- ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI000C1863E1 -----EKIIQDLLHETPYKVHLFVKNPKNEQFLfSHQIGEAFSSASIIKVPILLAALAYVE -KYSISLHSSLPISPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -EFLNDYFRQIGLQETLLQRKMMDVER-LAMGLDNFTSAWDMAHLFTRIYQQDLLAPPYNR -LVIDILNRQRA-HEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNSID-YLIGVFITN -VTEN-ELARQLIGRFSKVVYDH- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000F7AE676 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGGLLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDESKEAGSLFEQVGEAIS--- ->[subseq from] Uncharacterized protein n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9WKC7_9ACTN ----------RVVADANLNAGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQAFLDDGVLVTPDDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI00137C3DDA ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATIYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0007B6984F ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATIYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Beta-lactamase n=1 Tax=Thermobrachium celere DSM 8682 TaxID=941824 RepID=R7RQN3_9CLOT ----------DYIDRLNCSVGVYYKELETQYMF-EYNSDKIFPSASTIKVPILLALFNKVL -KGEIDLNKRIKIQKDYTVSGAGIVYLLDENNYTLLDLAKLMIVLSDNTATNIIIDLL-GF -EYINKYFKEIGLNETILQRKMMDFDRK-RLGFDNFTSARDLGLTFYKLCKKEVLNPYYCN -LAIEILKEQKL-KGGLDRYLGNKYEIAHKTGELNN-LEHDCGIVFKDHK-TFIVVILTEG -EEN-------------------- ->[subseq from] Uncharacterized protein n=2 Tax=Aneurinibacillus aneurinilyticus TaxID=1391 RepID=U1WRZ8_ANEAE --qKLREDVERAVSKVDGKVSVAIEA--DKEHI-SINANDPLPSASLIKVPIMIEAYRQAQ -EGKLSLVSEYSLLPEDRVGGMGVVSHLSPELLTLKDLISLMIIISDNTATNMVIRKV-GI -NTVNRLAADLNCGQTVLARMMMDHE-AVKLGKDNITSANDIVRFLKEIVEGRMLNEENKK -AAYDTLLNQQF-NTKLPAGFSLNATLAHKTGELP-GTEHDAGVFYINGK-HTYVAVLTTE -LS-DNASGQRMIAQVGKLVFDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriia bacterium 35-40-5 TaxID=1970579 RepID=A0A258KFC3_9BACT ----LLQDIKTELGKQAGFFALAFEDLQTRHQI-LWNADTEFHAASTMKTPVMIEVYKQVA -AGKRSLQEPVLVKNQSIVDGSDYQYTQIGTRIPLADLVYQMIIRSSNLATNLIIEMV-DG -KKVTQTMRGLGAKKIQVLRGVEDQK-AFDAHLNNTTTAKDLRLIYAKMAEGRIIDKNACA -DMIRILEDQTD-REIIPALLPANVKVAHKTGYIT-GVHHDSGIVFLPDGKKYVLVLLSKN -LT-DNAAAVASMAKVSEMIYRY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GR62_9BACT ------GELERLTAESKARAAVALHDFESGFRF-SLRGDRWFHAASTIKVAVLLAVFRAVD -QGRLGLSDSLHVRNRFLSAGSPFRYRAIGRTAKISALAEGMIRASSNLATNLLLDLL-GV -EYARRVLRDAGISGVELRRGVEDH-AAHEKGINNEVTADGLLTLLSAL-RGDFLSSESKE -QAIHILLGQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPERQPYLLAILTEF -DA-EQDGRRETVAAISEVIH--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus terrae TaxID=1914933 RepID=A0A429XDS2_9BACI ---TAEMQIKKLIDQAGGDWGIMVEDVENDISW-GYRTVASFPAESVIKIPIMAAVFSAVE -NKKLKLCDHVKVHLDDRVGGAGALQYLTPGILSVYDLLVLMIVQSDNTATNALIDLV-GI -EHIQQTLSETGMKDSSFQRKLMVYPA--QSDLQNTVTVADVNLMLRKLIDGQLVSRHACE -QMIQILKWQQF-RNGLPSKLPPKWELAHKTGWDTD-RQHDVGILFTGNRT-MIVSVLSDN -VS--SETAWNVMGDIGKIIYDY- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. AK53 TaxID=1406873 RepID=UPI000A36CFFF --eDLAKKIHTQIDSIDGTVAVAFYSLSKPKDSlLINVDEKFHAASTMKVPVMIELFKQAS -QGKINLQDSIVLKNESIVDDSLYRYNQIGSKVALKDLMHSMITISSNLATNVLIELV-DA -KMVTASMRDLGAENIEVLRGVEDLK-AYEKGLSNSTTAKDLMVIMKSIANNSAGTPKDCE -AMITILKDQQH-KSLIPFYLPEAVKVAHKTGSIT-GVHHDAGIVYLPDGNAYVLVLLSKN -LK-DFDKGTEQLARISKTLYDY- ->[subseq from] Beta-lactamase n=1 Tax=Pediococcus acidilactici D3 TaxID=1306952 RepID=R0GCN6_PEDAC ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDRDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A521TC22_9BACT ---SAKAEIERIIALSGAEVSVIYRPVGGHGEI-LINPDTTYHAASTMKVPVMIELFRQVD -AKLIKLDDQIPVSNHSIVDGSEYTFLAIGKTMSYRDLCEQMITISSNLATNVLMEKL-GV -ENIRATVAKLKAPGMNVLRGVEDQK-AFDKGMSNQTTARALMTLLTAIANGAAGSKSSCA -EMQAILKRQKF-NDGIPAGVPAEIAVAHKTGTIT-AIHHDAAIVYAK--EPYILVVMTRG -MP-DEKKSDLLIAEISRIIYR-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0008786AD5 ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Beta-lactamase n=1 Tax=Pediococcus acidilactici NGRI 0510Q TaxID=1229281 RepID=K9IBP6_PEDAC ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A5R9BD69_PEDAC ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0662_bin_9 TaxID=2605258 RepID=A0A6B1DQT3_9CHLR --sQLQDRVRDGLADCPGVAGFCLQDLATRDTM-GWHEQEVFPVASTIKIPILVTLLARAE -KGELDLQERIAITPAVLVPGSGVLTYLEGPLLSVLDIAQLMIMVSDNTATNLCIDWA-GM -DATNELMESLGLSQTRIRRKMQDHES-VARNEENVSTPADAVGLMRALYESRP-SSAVAE -QALAILKKPNRG--PIERAMEPGVAVSNKPGGMER-VRCDAGIVWLQRH-PYALAIMSKF -GMENYRHENRLVAAV-------- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7H097_9BACT ---TLRARLEARIAQAPAQVGLYYRSLARPDSI-LIGANLRLHAASTMKVPVMIQIFRDAD -AGLLELNDSLTVHTASLVQGAAFTYAVVGRNRSVRDLLELMITRSSNLATNILIERV-GA -SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAAGRAASRAACD -SMLVILGRQEF-NEGIPAGLPPGTRVAHKTGWIGEVVYHDAGVVYPPHGGSYVLVVLTGG -IKED-SVAHNLVADVSRMVWE-- ->[subseq from] serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=UPI0012CFB711 ---SLEEEVTEKIRRLPGKTGFYYENLVTGERA-AYHEDERMMAASVIKLFVMTEAFVRFE -EGTLSTDRIIRMKREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRMGYRDTVLQRKMYDTEKS-KRGIQNYITAAETGRLLREMYQGRLVSRQASE -KMISILKNQQL-CSKIPFYLQEEPEIAHKTGEDC-GITHDVGIVYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETSLWLY--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-29814 TaxID=1729688 RepID=UPI000835D834 ----LKAKIREELVGFRGRIGLAIEA--GDECI-YFNSEEVFPSASVIKVPILLAGLKQAE -EGYVNLDQLTVITE--RVGGSGVLQSLSSLALTIKDLLTLMITVSDNVATNMVIDLL-GI -EAINQEMERLGLKSTNLNRKMMDFA-AIQRGFDNVTCPSDMVKCLKAINEGAFLSAESKE -IALSIMHAQQF-LDKLPAMMPDRVFIANKTGGLPN-VEHDCAIFKYNGKT-AYAAVLTDQ -LT-DAYEAKLVISRIGKHVADY- ->[subseq from] Beta-lactamase n=1 Tax=Parabacteroides distasonis TaxID=823 RepID=A0A3D9A3X0_9BACT ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSA----DHTNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. FMUSA5-5 TaxID=2720023 RepID=UPI001439A137 -------AFDQLFRAAGVTGWLYAADVDTGHDV-GHGADEPMPTASMFKVPLLVALCRRAD -AGLLDLTERVTVTAADRVGGPTGLSSMLDDVISLRDLAYLMIALSDNTAADKLLGRV-GF -EAINTMLDAFGLEGTRVVQGSGEMLGVLDPSRTNRSTPREMVRLFGMIWRDEAASPESCA -WMRGVLNMQVW-PHRMASGFPDDVAVSGKTGTMPT-LRCETGVVEYPDGGRYAVSVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=UPI000F6013B8 ----------RVVADANLNAGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQAFLDDGVLVTPDDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7V1U9_9BACT -----------------ERLGIAFYDAETTLQW-SYNADLAFHAASTMKLAVLLAVFRQYT -RGELTLDEPVHVRNKSIYDRKPYMYDHLGRTMSVKQLAYYMITCSSNFATNLLVDVV-GV -PVIQTALDELKIDGIRVLRGVEDH-GAFEAGLNNEVTANGLLKLLRLVAEGKAYGEEASA -QMREILLDQRY-KSGIPAGLPQAARVAHKTGNIST-VHHDAGIVYLEGRKPYVLVILTQF -SSE--TGRTTAVADVSRDIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium CAG:110 TaxID=1263000 RepID=R5EIJ3_9FIRM --nDLASRLNAVMDAFPAKTALYCVDLTTGTPIvAIRENTRVVSASTIKVSILCCALQDVM -DGKLSLDQPLAIAPGDFCSDTEVFEPYRQDGASFWEMLYWMIVSSDNTATNTVISLL-GY -DHVNQYCRAIGLTQTSLQRKMLDFQ-AIAEGRNNYTSPADLYRVFSRLYHGEILNKALRE -VAFDFLSRCRS-TDALQRYIPDAVTVLHKPGGLDH-LNHDVGIFLTDDR-PYYLGIFTWD -GPDGQPQQNRLIGQLSRMIYDA- ->[subseq from] serine hydrolase n=1 Tax=Microbispora rosea TaxID=58117 RepID=UPI0004C3CB0B ---------ERVFRSAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELQRQAE -RGLFDLTERVGVPAADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNALLDGLGLTATRVVQNCREMLTALDPAVGNRSTPREMTRLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -FGQNQPRADAAIGAAARMAIDQ- ->[subseq from] Beta-lactamase class A n=2 Tax=Pseudomonas seleniipraecipitans TaxID=640205 RepID=A0A1G7SAZ6_9PSED ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANSLELKTDQLESDLDEAYRRYYQTGLNSATLVAYGQLLGKLASGELLSPESTE -LLYGIMGLDKYEAYRLEAGLDKALPFIQKTGTQQY-RACHVGVANPQDDNALVIVACAAE -LDEN-DEAGKLFEQVGEAV---- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JAU9_9BACT ---SLSAAIAARIAQTPARVGVYYRDLATGDSL-TVGSDVRFHAASTMKIPVMIQLFRDRD -AGLLSLDDSITVTNTSIVDSSPYQYKRAGAGASIRELIELMETVSSNLATNLLIAKV-DA -KRANATAHALGADSILVLRGVEDGK-AYRAGLNNTTTARDLGILLAAIANETAASARSCR -DMLAILGRQHF-NEGIPAGLPAGTRIYHKTGWIGQVVYHDAAFVEPPGGRGYVLVVLTGG -IQT-DDDDHALARDVSKLVFE-- ->[subseq from] serine hydrolase n=1 Tax=Bacteria TaxID=2 RepID=UPI00056F2F4E -------KILDILNGIPGKTGFYYKNLTTGEKW-EVRSEEPMIAASVIKIPVLAEVFAQLE -AGTADKNELYRIREEDKLPSCGALNMHTGLEVTLEDLYTLMIILSDNTATNLLIKKF-GM -ENINRRMRSLGLNVTTVNRLLFDAGAS-AAGRENRICAKEIGLLLEKMYRGELISPKASQ -EMISILMNQRL-NGKMPFHFKGKVKIAHKTGEDG-GITHDVGIVFAPQP--F-VACFCSN -ET-DVPLFERAIQDITKLLYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacteraeota bacterium TaxID=2052317 RepID=A0A2W5X8Z2_9BACT ---ELQLQLASISLHAPGHVAMEIKDLGSGAIS-SVNARASMPAASTIKIPVMVEVFRQLS -NGRFDFNTTVGLRRSDKDWGSGSLCNRAGTRYSVLRLLKAMITVSDNTATNMLIRLV-GR -QNINDDMLSIGLQHTRLSDYIRSQGDDIR--YALRSSPADMVMLLEQMAGNELIDRWSSR -EMISILEGQRH-NGLLPEPLPMGLPIAHKTGTLHD-TLNDVGIVFADPQ-PYVIAVMTTN -LP-SLSAGRRFIRGVSRLAYDQ- ->[subseq from] Serine hydrolase n=2 Tax=Streptosporangiales TaxID=85012 RepID=A0A1V0A8N3_9ACTN -------AFDQLFRAAGVTGWLYAADVDTGHDV-GHGADEPMPTASMFKVPLLVALCRRAD -AGLLDLTERVTVTAADRVGGPTGLSSMLDDVISLRDLAYLMIALSDNTAADKLLGRV-GF -EAINTMLDTFGLEGTRVVQGSGEMLGVLDPSRTNRSTPREMVRLFGMIWRDEAASPESCA -WMRGVLNMQVW-PHRMASGFPDDVAVSGKTGTMPT-LRCETGVVEYPDGGRYAVSVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=2 Tax=Kribbella soli TaxID=1124743 RepID=A0A4R0H7A3_9ACTN -------ELESLRERKPLGIGIYVKRLTTGEEA-AVRADVVFETQSVIKLAVAIRCYQLAD -DGRLDLDERIRVTRSDIVGGSGVIRYFQEGLPTVRDLLTAMIVVSDNSATDLLLARVGGV -ADLNAWLAASGYTQTRMAQSLLDADRG---L-PGQMTPREAGRMLESIEHATAVSGKSSA -ELRGALRQQQLGERRLPQFVE--HPVGHKTGDNPPWDANDVGIIYSPSG-PIVVAVFAND -LGGVYEQEEDRIGRIGRVIVDHf ->[subseq from] class A beta-lactamase n=1 Tax=Muribaculum sp. TLL-A4 TaxID=2530390 RepID=UPI00143DF3D7 ----LKEKLTQYIADKNARIGIALL-VNGRYSV-SVNGDDAFPMLSVYKFPIAMAVAEYCR -MRDIDFSDSCLVTAGDLHRYSPMLQKYAEVDITFDELLTYALQQSDNNASDILLNRIGGA -TSANEYVSGIGIEGVTIKWSEDDMHIDMSRCYENSATPLAMAKLMWTFDFQ--CNDTLSK -RIKQLMESCETGQGRLAKPLEANAVIGHKTGTGFVNAVNDAGYVHLPDGTRYSIAVFIAD -SHYDMEHTEDIIADISEMTA--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. N3536 TaxID=2666127 RepID=A0A6B8K739_9BACI ---ELISKVQKLIKPSKGTWGILLEDLNTGDKW-EYNEQELFYAASVIKVPIMVAVFRAVE -RLELSLSDLIILDKDEYVGGSGVLQHLTPGTLPLSDIILLMIIQSDNTATNLLIDLV-GV -ENIKQTMKEAGMEHSTFYNKLMLSKPN--PHGTNRIAAKDVGILLTKIAQGEIVSEQASK -QMIEIMKKQQM-RDCLPEKLPPAWEFANKGGWIP-GTRHDVGIFFVGDRK-LVATVLSEK -ED--DVLAKRILSQIGYEIYQY- ->[subseq from] Uncharacterized protein n=1 Tax=Sporosarcina globispora TaxID=1459 RepID=A0A0M0G7G7_SPOGL --nTLKAEILDLASCCEGRAGVYVHT-EDG-VI-AANADDVFSSASLIKVPILLAGLSQAD -KGLLHLEEEVEVKDAARVGGAGVLQAMSKDLFKVIDLMTLMIIVSDNTATNLIIELL-GK -EKINQLIKGFGFQYTELNRVMMDFK-ALKNGIDNTTTARDMAIGLKALAEHSLLSGKYTE -RALHILEKQQYKNKLANTMDTEKVKVASKTGELP-GIEHDCAIFTRNEK-TVYAAVLVDQ -LY-NQSAGKEVLSSIGRRIYQY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium 13_1_40CM_66_11 TaxID=1805195 RepID=A0A1Q7E875_9BACT ---SLRARVEARIAQAPARVGLYYRDLTTGDSL-TVGSDVRFHAASTMKIPVMIQLFRDRD -AGLLSLGDSVPITNTSIVDSSPYQYRGLGQRASIHDLIELMETVSSNLATNLLIAKV-DA -KRANATAHALGADSILVLRGVEDD-KAYRAGLNNTTTARDLGMLLAAIANARAASPASCK -EMLAILGRQHF-KEGIPAGLPPGTPVYHKTGWIGQVVYHDAALVEPPHGGRYVLVVLTGG -IQKD-EDSHALVRDLSKLVFD-- ->[subseq from] Putative beta-lactamase n=1 Tax=Algoriphagus machipongonensis TaxID=388413 RepID=A3HV13_9BACT -----KELVSAQIASIQGDVAVAFINLSDPSDNlMIQADEEFHAASTMKVPVMIELFKQEE -EGKLNLDDSILLVNESIVDGSSYSYNKIGTKVSLNDLMYNMITVSSNLATNVLIELV-DA -KKVTATMRDLGAAKIEVLRGVEDQK-AYDLGLSNSTTARDLLEIMEAIALNEAGTQEDCQ -EMISILKDQKF-NEIIPFHLPEGVSVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LA-DFDKGTEQLAGISQTIYEH- ->[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A1C4U2Y8_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=A0A1S2SVL9_PEDAC ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGGLSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00066CC434 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSRLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Aliifodinibius halophilus TaxID=1736908 RepID=UPI0013EAB784 ----LKSKIKKQLKKVKGDFAVAFKNLSDTSQAiYINEREKFHAASTMKTPVMIELFNQAE -NGRFSLDDSITVKNESIVDSSRYEYDMIGKKRSIRQLITDMITMSSNLATNILIQKV-GA -HNVTQTMRSYGVDSIMVLRGVEDIK-AYEKGLSNRTTALDEAIIYEQLGKGQAVSREASE -AMIEILIEQHF-NEMIPAQLPESVVVAHKTGWIT-GVNHDAGLIILPNGHKYVLVLLSKN -AP-NRERVQSAFADISGDIY--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Streptomyces sp. WAC 01420 TaxID=2203203 RepID=A0A428ZCY1_9ACTN ------------------------------------------------------------- ----------------------------------------------DNTAANLLLTTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIVHD- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Lentibacillus salicampi TaxID=175306 RepID=A0A4Y9A9H0_9BACI --eQLEADVHSLMLDFDSPVGLVIKE--GNDTI-NINEDVPMPAASVIKIPIMMEAFRQAE -NGLLDLSQNMEIPTDAIVGGSGVLQFLSERVMSLLDFLTLMIIVSDNTASNLALEQT-GI -ENVNNLCRDLECHHTEVQRYFMDMKAA-ESGFENTTTAGDMVKFLEEIASPKLLTKKSAG -HIFDIMTGQQL-TSKLPAYHANDVVIANKTGELAI-AQHDVGIFKYQDKT-VLAAVMTDR -IT-DHIAIQQTIARIGKAIMSY- ->[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N6AMH9_9ACTN -------------------SGVTVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGRVSLDDGVLVTPADVVGGTGQLQFETPQVVTLRRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAAL-RGEENYTSPDDVVSLLGAVWEAEILSPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGSE-TAVAFLTAG -PM---DTGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Halomonas urumqiensis TaxID=1684789 RepID=A0A2N7UQS7_9GAMM --qRLEARLETLEDAFEGELGVHVRVLGSDERF-GFRDDERWYLASLIKVPVAIELMSRVE -RGEASLATSLTLAESDYVDGAGPTNWSPGTSLRLEELLEPMLTVSDNTATDMLIRHL-GL -EAVNRRAALLAGVGFGPITTLVDVRRAYYASGLNAGRLDAYANLLAALGEGRALGPRATA -ELLSIMQATTSGENRLKAGIGPEPRFAHKTGTQHR-RACDAGIVLPEQGQRIVVVACTRG -P-LETTLHERALAAIGVAL---- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JHK8_9BACT ---SLESRLRQVRDEVDGRLAVYVENVATGERV-AIDADSPYETFSVIKVPLMATVLERVR -DGRLSLSDRITLTAGQRRIPSGVLYALDAGLPTVKDLLTLMIVISDNEATDALGDLV-GR -EEVTRAMARLGLPNTRLRFSDLEWDREETGLYFGRSTARETGRLFALMAKGELVSKEASA -LMVSILKRQQV-NNRFPRYLGADVEVAHKTGDGQPWVANDAGILWVKGT-PIVLVAFAGH -HRGTTEEIHEAEARIAAIVADHf ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NCD5_9ACTN -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWVLVELLRRVD -CGQVFLDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U3X5_9BACT --eKLRARIEAVDRGLDGVLGVSVKDLKGGMTL-DVRPAEPFPQASSIKLAVLYELYRQAE -EGRVDLGEL-TRPPLPRVRGGGVLQELGNQVLTWRDVAVLMMGWSDNAATNVLIDRV-GM -DAVNRRLDLLGLRATRLRRKMMDLEAARRG-DENVSTPAEMRQLAETMYAGAGLSKERAR -DMMAVAAVPKE--SPFREPLPEGLVVADKPGSLE-AVRCVTAIVDLPGR-PYAVSIMTTY -LRRD-ADGAAAIREISAALYETf ->[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A150WBR6_BDEBC ------------------------------------------------------------- ------------------------------------------------------------- --RYEAFAKLIQVPVSELKTSIEEAFEKYYARGLNSTTLRSFGSLLEKLARGQVLNKAHTA -LVLKYMQEMKTGENRLKAGLPKDVVFAQKTGTQV-ARMCNVGIAASKKKQQKTVIVACAE -KYLDQAGAEKVLKKMADALTE-- ->[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9VTJ3_9ZZZZ ------------------------------------------------------------- ------------------------------------------------------------- -----ALARTLGVTDTFTQPDYDRAFDAYEATGENVGTLSAFGDLLASLHQGHALDAEHRQ -VLLDVMRRTSSGKQRLKAGMGEDISFAHKTGTQQR-RSCDAGIAERANVGAWVI-VTCTR -GPAALSAHERAMASVGEAL---- ->[subseq from] Serine hydrolase n=1 Tax=Echinicola sp. LN3S3 TaxID=2591634 RepID=A0A514CMB5_9BACT ---ELHQAIDSRLNKEEGDFAVAFRSLGADPVTlLINEKETFHAASTMKTPVMIELYKQVA -LGTISLDDSVKIVNESIVDGSPYRYSKIGQFSTYRELNFEMITMSSNLATNILIDKL-DA -KKVTETMRSLGAKDINVLRGVEDLK-AYEQGLSNTTTAHDLMLIMEAIAEGKAVSKEASL -AMFEVLKAQHF-NEIIPGQLPEDVTVAHKTGSIT-GVRHDSGIVELASGKRYVLVLLSKN -LKAP-EEGIQAMSDISKLLYD-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus borstelensis TaxID=45462 RepID=UPI000F0829D4 --kSLQEKLETIIAAAGGQWGVVVEEINGSFYW-EHNTTQTFAAESIIKVPIMAAVFDAAS -KGNVRFDQAVRMKQTDQVAGSGVMQHLTPDAYPVYDLITLMIIQSDNTATNMLIDLI-GE -DQVRLTMAELGMHDSCYSRKLMLYPAD--SPPNNMITAGDIARMLKRLATGTFLGEHACR -QMIGIMKKQQV-RNALPARLPAVWEMANKTGWDT-GRQHDVGILFAGGK-AYSLTALSEN -APPD--ASLQAMAAIGYEVY--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=UPI0013E93DD1 --------ILDFMKDKNLKYSILIKDLNSDKSC-CINEEEVVPSASIIKLFIMAKTFQLVS -NGELNLSDRISINKEERVPYSIIYVLDDRNTYTIRDLITLMIIQSDNTATNQLIHML-GI -ENINKFIGELGFKNTILKRKMMDFDARVL-GMDNYTTAHDVAKLLELMDKGQLISKTYSD -MMIKITQMQLD-NSMMRINLDEELIVAHKTGDLPN-IKHDVGIVYARHK-HYIFNMLTWD -ATCD-NYARDIIGKVSKISYEY- ->[subseq from] Serine hydrolase n=1 Tax=Variovorax paradoxus TaxID=34073 RepID=A0A2W5IMW9_VARPD ------------------------------------------------------------- ------------------------------------------------------------- -QRAEAVRRALELPPDALRTDIDAAYAGYYAEGRNSATLVGYGAMLERLVRGELLSRTSTE -RLFQAMKFGTRGNYRLEAGLPKNLRLIHKTGTQHQ-RACHMGVVQPQDGDATVVAVCAAE -LD-EQRAAGRLFEAVGRAIA--- ->[subseq from] Serine hydrolase n=1 Tax=Luteimonas terrae TaxID=1530191 RepID=A0A4R5UFH5_9GAMM ---TLDHHVRAIDARLTGELGVHVQRLDGGTQY-GFRADEVWYLASGVKVPIAIAVLREIE -QGWLTLDTQVTLRADDFVDGAGGTNAHRAGDLTIAWLLEQMIVHSDNTASDVLIRTV-GL -GQVNTVASELIARDVRITSL-ADVRRSYYATHANSATLRDYGHMLGALQAGDALGPEGTR -YLLDVMARVQTGKQRIRAGLPTGARFAHKTGTQYR-RICDSGIVTVPARAPVQVVVAACV -RGAGTAASERALRELGAALT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q3V9K9_9BACT --dSLRNKISRTAGSINARVGVSMLLLESGDTL-SYRAEERFPMMSVYKLPIAIAVLKELD -RGTIFMEKYLLIQKDSIQTGEEEMYAFPDRKITVGQLLTLMLVQGSNTACDLLLSMMRGP -SGIQPYLDDLDIHDMAITNTEREINANPILKDNNWTTPNELVRLLTIAYSSDYLSTKNHD -FLWDKMTETVTGPDRLKALLPKNTLVAHRTGTG--------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas stutzeri B1SMN1 TaxID=1212549 RepID=S6JRL7_PSEST ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGHAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Paraflavitalea soli TaxID=2315862 RepID=A0A3B7MPC5_9BACT ---QLKQAITTELAKNEGQFAVAFSDPATCTTL-LINADSSFHAASTMKTPVLIEVYKQAA -AGTLSLTDSVLVKNESIVDSSTYSYTLIGTKRTLYDLVYDMIIMSSNLATNIVIEKA-DA -KKVTQTMRDLGAKDIQVLRGVEDSK-AYQQGLNNTTTAYDLMVIFQKMAAGETVDSAASQ -AMINILLDQHF-NEIIPAKLPKDIKVAHKTGNIT-GVQHDSGIVFLPDGRKYVLVLLSKG -IK-DEKAAVASMARVSEMIYQY- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0007F0071B ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTIPIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGT-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Flavobacteriaceae bacterium MT2-5-19 TaxID=2607999 RepID=UPI0011EC6C4A -------HIRTQIDAIDGEVAVAFQNLSDDDRL-LIHGDETFHAASTMKVPVMIELFKQQR -EGLIDLNDSILLVNESIVDGSPYQYNNIGQKMTFYDLLYPMITVSSNLATNVLIEWA-DA -KKVTATMRDLGAQNIEVLRGVEDIK-AYELGLSNTTTARDLMIIMQAIAEHKAGSPADCK -EMLRILKDQRF-NEIIPFYLPDSVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LE-NFEEGTEQLAGISKTIYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A2V2ZPF7_9BACI ---KLKAEILELANRCEGRVGAYIQT--EEGII-EENCSKVFSSASLIKVPILFAGLSQTE -NGLLQLEKEVQINNAVRVGGSGVLQSMSKELMKVIDLMTLMIIVSDNTATNLIIDLL-GK -EKINGYMKNIGLKNTELNRKMMDFES-LKKGIDNTTTARDMAFCLESLAERSILSEENKA -LARRILDGQQYKNKLANTVDQEKVQVANKTGELP-GIEHDCGIFTGNGR-TVYAAVLVDQ -LKN-QAAGREVLSFIGSRIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A350UGI2_9BACT ---------GKLKRETGGDAWWYAKHLESGREE-AYRADERVRTASTIKLPIMAAAFDLAE -RGELKWDERITLRREDIVSGSGILQEMTGGEFRVDDLVKLMIVVSDNTATNLVLERV-GG -DRVNGFLEGLGLAETRTLRRIRGDGTENARFGSGVSTSREMGRLAAMLHQGRVVSRAASR -AMVEILKRQQY-KDCIGRRLGSGVVVASKSGALD-ALRSDVALVTGKGGT-FVLAITVDG -MKSEDNLGSIAIAEMAKALV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6Y8B8_9BACT ---KLKQKILAELHKYKGTYAVAFKDLSSGDEL-LINEHENFHAASTMKTPVMIEVFKQAA -LGKFALTDSVTIKNESIVDGSLFSYRQIGQKRAIKDLVYEMIIVSSNLATNIIIDLI-DA -KNVTQTMRDFGAKDIQILRGVEDSK-AFQQNLNNTVNAYDLKIIFEGIANGKVVDQKSCD -AMIKILLDQKF-NDIIPGKLPKNVRVAHKTGSISK-VQHDSGIVLLPDGRKYVLVLLSKD -WD-DEKSNKKMLAGISEMIY--- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-066ASC TaxID=1729723 RepID=A0A0T6VPP4_9PSED ----FLAHIARVDDQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE -EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL -ERVNTVTRELVPQGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR -YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPEISRRLLIVACVR -EAASTAKAERALRGTGEAVT--- ->[subseq from] Beta-lactamase class A n=1 Tax=Fictibacillus sp. BK138 TaxID=2512121 RepID=A0A4Q7QRD7_9BACI --kQIENDLLRLISSGKGTYGVSIYHFETEEEF-IHNQNEEFYAASIIKILIMSAVFAQVS -EGKRSLSDKIQVRSEDIVSGDGILKNLSPGMWTVHDLIVLMIIESDNTATNLLIDMV-GV -ENIQLYMTIWGFKQTQFRHKLQI-KPSRNHNDSNLITAKEMNHFLRNIAMGNIVSMSVCR -KMIDIMKQQKM-NDLLPRLLPEYWEMAHKTGYVP-GVEHNVGLFYIPGHT-FAISVLSKN -VP-NRDEPKRIMGDLGLMLF--- ->[subseq from] serine hydrolase n=1 Tax=Pseudoflavitalea rhizosphaerae TaxID=1884793 RepID=UPI000F8D2D5B -------------NHPEGYFAIAFKDLSTGKTF-FMNEHASFHAASTMKTPVLIETFRQAS -KGKFRIEDSIEIKNSSIVDGSPYSYTHIGQKLPVSDVLHRMITKSSNLATNIMIDLV-DA -KKVMVTMRKLGAKDMRVLRGVEDDK-AFEKGLNNTTTAYDLMLIMEHLEKGTAVNRRASE -AMIKILMDQHF-RDVIPAKLPAGTKVASKSGSIT-GICHDSGIVFLPDGKKYVIVLLSKG -IK-DHKVATNTLANASRIIYDHy ->[subseq from] Uncharacterized protein n=2 Tax=Cytophagales TaxID=768507 RepID=A0A1Z9SCY8_9BACT ----LENKISNLIKSHKGTFAVALKSLDDGNTI-LINENEIFHAASTMKTPVMIELFKKKH -NGEVSFEDSLQIKNESIVDGSKFXYKKLGKYISIRELVSAMITKSSNFSTNLLIDYI-NV -KNVNKTMRDMGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGSFINPSISN -EMVEILKNQVY-KDIIPKYLPDNIEVAHKTGWIS-GVRHDSGIVFLENGKKYVLILLSKN -LDD-DIEGAEFLAKISLEIFN-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. KC207 TaxID=2530377 RepID=A0A4R4R1L5_9ACTN -------ELAALERRFDARLGVYAVDTGTGRTL-AHRADERFAYASTFKALAAGALLAATS ---DAELDRIVRYERADLVPHSPVTEQHVAGGMTLRAVADAAVRYSDNTAANLMLAELGGP -AGFERVLRGIGDTVTDPARTETSLNEAAPPR----------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A534A5K0_9BACT ---TLRARLEARIAQAPAQVGLYYRSLARPDSI-LIGANLRLHAASTMKVPVMIQIFRDAD -AGLLELNDSLTVHTASLVQGAAFTYAVVGQNRSVRDLLELMITRSSNLATNILIERV-GA -SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAAGRAASRAACD -SMLVILGRQEF-NEGIPAGVPSGTRVAHKTGWIGEVVYHDAGVVYPPHGGSYVLVVLTGG -IKED-SVAHNLVADVSRMVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Echinicola strongylocentroti TaxID=1795355 RepID=A0A2Z4IET5_9BACT ---ELREAINTRLDKVEGDFAVAFRSMGAEPVTlLINEKETFHAASTMKTPVMIALYKQVA -AGNIALDDSVKIVNESIVDGSPYSYGKIGQYSTYRELNFQMIMMSSNLATNILIDKL-DA -KKVTEAMRSLGAKDIEVLRGVEDLK-AYEQGLSNTTTAYDLMLIMEAIAGGKAVSEEASL -AMFEVLKAQHF-NEIIPGQLPKNVTVAHKTGSIT-GVRHDSGIVELPDGRRYVLVLLSKN -LKVP-SEGIEAMADVSRMLYEY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000B886BE3 -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-066ASC TaxID=1729723 RepID=UPI000A86E714 ----FLAHIARVDDQTPGRLGVYVKDMETGIST-SYHGEEPWYLASTVKVPVAITVMRRIE -EGALSLDTGVPLLASDYVDGAGATNGFAPNTHSVRFLMEQMLIHSDNTASDMLIRLV-GL -ERVNTVTRELVPQGFGPITTLADVRRRYYATPYNSATLKAYGDLLSALDAGTALNPDSTR -YLLGVMRRAETGARRIKAGLPPTVGFAHKTGTQR-ARICDAGLVDQPEISRRLLIVACVR -EAASTAKAERALRGTGEAVT--- ->[subseq from] serine hydrolase n=1 Tax=Nocardia acidivorans TaxID=404580 RepID=UPI00082FD67B ---------------------------DPGTEV-AVDAHERVVTASVYKLPLFVAFCRGVE -AGRIDPTARITVTPSDCTPPTGIAALHDPVTMSWRDLATSMMTVSDNAAADVLLGEV-GL -GPVEDLLRDLGLHETRIVGGTADQFEAYDPTYASATTPEEMTRFLSALWTGALLTPAHTD -FVRAVMRNQVW-PHRIAAGFPRGVTVAGKTGTVGI-IRNEVAVVEFPHEHPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=UPI0011AADC03 ---TAEIQIKKLIDQAGGDWGIMVEDVENDISW-GYRTVDSFPAESVIKIPIMIAVFSVVE -NKELKLCDPVKIRLDDQVGGSGALQYLTPGILSVYDLLVLMIVQSDNTATNVLIDLV-GI -EHIQRTLLETGMKDSSFQRKLMVYPA--QSDLQNTVSAADVTLMLRKLIEGQLVSRHACE -QMIQILKWQQF-RNGLPSKLPPKWELAHKTGWDTD-RQHDVGILFTGNRT-MIVSVLSDN -VS--SEAAWNVMGDIGKIIYDY- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00115902F9 ------------------------------------------------------------- ------------------------------------------------------LATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLSAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. DR205 TaxID=2713573 RepID=UPI0013E4F3B2 --rKLEKQIKQLIQGFQGEVGIYVHNLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE -KGQLQLDQELIYRESQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG -MAINTLMADLQLQHTRVNSQTEGRKTDWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD -RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN -NEGKTNAAEVLTRKLSKLLWDYy ->[subseq from] Uncharacterized protein n=1 Tax=Thermoactinomyces vulgaris TaxID=2026 RepID=A0A0N0H902_THEVU ---RLIQNLEHWKSNAVGNWGVWIEDLTSGTTW-VWNETKSFYAASIIKVPIMVAVYKQAF -LGRLALTDEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT -ETIRETMDELGMRQSTFYNKLMIVPAAPAG--LNLITAADVAQCFRHIAQGKAVSQHASR -QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTR-TLHDAGILYTKSRA-MVMVALSEE -CE--YEQAQQQMKQLARLVYE-- ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI0006B46177 -------ELQNVIQTLPGRYAVFAKNLETHKIF-AYHEHDIFPSASVIKVPILIELYRRVE -EDHLSLDHLLLMRKEDQVGGSGVLKDLTPGTYSLRDLATLMITVSDNTATNLLIDYL-GV -EWVNSTIRRLGAQNTELIRKLQRVPAE--YDQINHTCAFDMALLMEKLATGTAISLAVSE -QMVNLLTRCQG-PVSITKEPAAAVIIAHKTGSLSE-ASHDVGIVYSPHI-NYVAAILSEG -AP--------------------- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0009A262C5 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGAMLEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDLPFIQKTGTQLE-RACHVGVIEPEDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6AC48_9BACT ---TLADELERLTAESKARAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAQGMISASSNLATNLLLDFV-GV -EYARKVLQDAQVSGVELRRGVEDH-AAHERGINNEVTANGLLMLLSA-VRGDFLSNQSKE -QAIRILLEQRS-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EQEGRRETVAAISEVIYR-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=UPI00114F4B83 --------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus centrosporus TaxID=54910 RepID=UPI000F0A3CE1 --eQLREKLTQLLDKAEGSWGVVVEDLDRGQRF-AHRPDEAFIAESVIKVPIMAAVYAAAA -QAAFQLDERIPMRAEDQVGGSGILFALSPGLLTIREWVTLMIIQSDNTATNVLIDLV-GR -QRIEQTMIELGMEKSKYSRKLMIYPVG--ITENNMITPGDVSRMLGSIATGGFLSHHACE -EMVSIMKRQQV-LNGLPSLLPPDWEIACKSGWDS-GRQHDVGVFFSQGR-RFSIVALSQD -VQ--SESALRVLGQIGKEVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RLP9_9BACT ---TLGEHVERLAAQSKARVAVALHDLKSGLRF-SLHGDRWFHAASTIKVAVLLAVLRAAD -EGRLRLDDSLHVRNRFISVGFPFHYNRIGRTAKISELAEGMISASSNLATNLLLDFL-GV -EYARKVLRDAQADGVELRRGVEDH-AAHERGLNNQVTANGLLRLLSAL-RGDFLSAKSKE -QAIRILLEQRF-DSMIPAGLPPHAVVAHKTGEIST-ACHDMGIVYLPEREPYLAVILTEF -DS-DRDGRRETVAAISEVIYR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A3S7Q8H3_9BACT ------------------------------------------------------------- --------------------------------------------YSDYTAMNKLIAHLGGP -DKVTAFARGIGDDTFRLDRTEPTLNTAIPGDPRDTTTPLAMAQTLRHLTLGSALGETQRA -QLVAWLKGNTTGAASIQAGLPTSWVVGDKTGSGDYGTTNDIAGHLAEGRAPLILV----- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sediminibacterium sp. WSJ-3 TaxID=2698829 RepID=UPI0013795FEA ----VSAEIKRLFAGQRGVFAMAFRNSQTGETI-LINEQESFHAASTMKTPVMIELFRLDG -LKKIRLTDSVVVRNSSIVDSSGYSYTQIGTKKTIGDLLYQMIIKSSNLATNLLIELA-DA -RQVTQTMRQLGAEKTQVLRGVEDSK-AYRKGWNNTTTALDLMTIYDKMARAEIIDAKACD -EMIGILLDQQF-NEIIPAKLPKEVRVAHKTGSIT-GVQHDSGIVLLPDGRKYVLVLLSKN -LE-DEKAAVETLAAVSELVYRY- ->[subseq from] Serine hydrolase n=1 Tax=Luteimonas terrae TaxID=1530191 RepID=A0A4R5UF82_9GAMM ------------------------------------------------------------- ----------------------------------------------DNMAIVRLRNADAGE -ARLQALARELGVARTDLDATLEGVFDAYYRSDRNTATLPAFATLLDRLAAGELLSPDSTR -LMLDHMRGISTGDRRISAGLPPGTDFAQKTGTQLR-RACNVGVVDPEARDGATLVLACAE -DFDDIADAETAFQGLGRAL---- ->[subseq from] Serine hydrolase n=1 Tax=Caldilineaceae bacterium SB0661_bin_32 TaxID=2605255 RepID=A0A6B1DA36_9CHLR ---SLESDIRDITADSGAEMAVSALHLESGQRF-DVDAERVYPLCSVLKIPVLVEAFRQIE -EGLFTLDDRWQLTTAEKNLPSGILVFFDDGLPTVRDLLTLMIIISDNTATDMVMHRL-GE -GSVTRAMHDLGLTDIHVPLTIRELFDYSLGPDNDTGTPAALTELLARIWRGETVSRAACD -AMLDILLKQQL-NDRLPRYLPPGTPCAHKTGTLP-GIRNDSGIIYAGENAHVAVTAFSLW -DD--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A366F136_9BACI -----EVKILDAIDKCMGRVSVAI-DLP-SRSI-QINDDTPYPAASLIKVPILLEGFRQAE -QGGICLNETVMVPKEDRVGRAGVLSALSGNMLTVEDLLTLMIIVSDNTATNLLIDRI-GA -EAINNLCNSLALKHTKLSRKLMDFQSM-EQGYDNLTSASDIITCLRILDQSPLFSEQSRE -KMLSILHQQQF-DTKLPARIDERVFIANKTGELP-GVEHDCAIVRCNQK-TAYIAVLIDG -LEEN-ESARGTIAEIGKLLYDY- ->[subseq from] serine hydrolase n=1 Tax=Flavobacteriaceae bacterium S2-4-21 TaxID=2607998 RepID=UPI0011F00965 -------HIRTQIDAIDGEVAVAFQNLSDDDRL-LIHGDETFHAASTMKVPVMIELFKQQR -EGLIDLNDSILLVNESIVDGSPYQYSNIGQKMTFYDLLYPMITVSSNLATNVLIEWA-DA -KKVTATMRDLGAQNIEVLRGVEDIK-AYELGLSNTTTARDLMVIMQAIAEHKAGSPDDCK -EMLRILKDQRF-NEIIPFYLPDSVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LE-NFEEGTEQLAGISKTIYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7PBP6_9BACT ---SLRDALSPLLAAHEGVATAAVRDLKTGVGF-SAGADRPMPLASLVKVPVMVAAYAAAH -EGRLSLDEQITFAADDVVPGSTVIDKLSPGAFTLRDAVRMMIASSDNTATNLVIRRI-GL -PATNVVMDRVGLSGIRLNRRETSLDVRSREFGLGNGTAAELVTLMGMLHQDGIVAEGACE -AMLGHLLACED-RGTAGRDMPAGVKVAHKTGLVS-GVRTDAGLILGPAG-PIAFCLLTKD -NRAPGGPADDLIAKVARAALD-- ->[subseq from] Serine hydrolase n=1 Tax=Aminipila sp. JN-18 TaxID=2507160 RepID=A0A410PU39_9FIRM ------DEIIEKISKADGKVGFYYKNLVTGEEI-KFNENETFRPASVIKLPIFAEISRRDA -LKTADMAEKIVIKNSEKVPSCGALTLFTDEPVDIRTLCNLMIAISDNTATNVLIKRF-GI -EALNEGFRIMGLEKTRVNRLLFDMEAA-AQGKENVVVPQEIGRLLEKIYRKEFVNEEVSE -KIAETLLAQQV-NHKIPGRLPEEIGVAHKTGDDD-GITNDVGIVYAK--EPFVIVFLSNE -TD--VPAFEQIIRDVT------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium siyangense TaxID=459529 RepID=A0A420G4X2_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -VAINKLMSELQLTQTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSQKSSD -QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NVGKTNEAEALTRKLSKLLWDYy ->[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA11991 TaxID=2055789 RepID=A0A3D0SHL1_9CYAN ---SLKAELLSLMENYTIKPAIYVWDYESQNYV-DINASKIYPVASIIKIPVLIDLFKSIE -NKSVSLNEKIPLTEYYRSEGSGNLQFMAGNSWTVDNLARIMITNSDNSATNMLMSKIGAM -TEVNQSIRDWGLKNTEIQTWLPDMKGT------NHSTAREIAQMLYNIDTDEFLSDKSRN -KIYDYMSHVHN-DRLIQAGLRAGSTFYHKTGDIGT-MLGDAGIVVTPNGGRYIVVILATR -PHNS-VLGKEFIVKASQIIYNY- ->[subseq from] Beta-lactamase class A n=2 Tax=Candidatus Chrysopegis kryptomonas TaxID=1633643 RepID=A0A0P1NTU9_9BACT --kQLISKIQDVAEKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYRFN -EGKLKKDTLINLEDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL -DAVNNRMKSLGLNNTKILNKLMSFKTNTPESLRGYTTPNDMVKLLELLAGGKIISPETSA -EIINIMKNNQD-YEMMKRYLPEKVTVANKTGSIDR-MKADIGIVYSQCT-SYAVAIFCDQ -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus soli TaxID=220688 RepID=UPI0008260BCF ---KLETKLKEELLGCDGRLGLAIEI--GNEQF-LYQSEAVFQSASVIKVPILIEGLRQSD -QGKIKLDEVTAITN--KVGGSGVLQALSGHAMTIKDLMTLMITVSDNTATNMLIDLL-GM -ESINLTMEKLGLSNTVLNRKMMDFE-AIERGWDNFTSPIDMITCLKAVNEGSFLAKESKK -AALEMMNNQQF-LDKLPAMMDDKIFVANKTGGLP-GVEHDCAVIKYRGKT-AYIAVLMDK -LN-DVSAGTQTISRIGRRLYEY- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A6B1BGJ5_9BACT ------------EHESPGTIGVSVIS-PQGERW-ASRGDHQFPAASTVKIPIMIEIYRAID -RGTLALDDTYIVRSVDKSPGSGVLRHHTGLQLSFGDLLYLMMSISDNTATNILIEVA-GM -DRINETMRELGMTASTLGRPMRGRL-AVEGEQENWATPNNYTAVVKTILDDQAASPASCQ -AMLTTLTQQQN-GRRIGRYVPKTYRWGSKTGSNR-GIINDVGFVESPAGT-MVIALYSLK -LG-DHVTGECALSEIAKVAMQ-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium acetobutylicum TaxID=1488 RepID=UPI0005431BC6 ----LKKTIENLITSNKEDISLVFLDLKNPSNHiYIKENKVFPSASTIKVLIMAEALNEVL -SGNHALEKKIEIKSSDKVNYSIITC-LTNKIYPLIDLLTLMIISSDNTAANILIDLL-TM -DSINKYGKKIGLKTTLLRRKMMDSNAA-KEGRENITTAFDMLTLFSKIYNKKILSPDMCN -LMLNILSNNTD-CEVLLRYLCDDIRCAHKTGDLPH-LNHDIGIFKTENA-EYILGVFVRN -AQFN-YEAKDIIGRISKEIH--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000FF32242 ---TVEGTIQDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLTGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNEN-HTKLPHDLPAEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7EEY3_9BACT ---TLRHQIEKIEKESGATIAVALRDFESGLEL-HYHADRWFHAASTIKVPILLGVFAAID -RGELLPHSRVHVRNRFLSVNIPFRHNAIGKMMRVDELAYHMITTSSNLATNLLLGVM-GT -DAVNETLKELHDKGIELRRGVEDEL-AFEKRINNMVTADGLLRILVMLAEGKAFSPGLCR -RMMDILHGQEF-NQGIPARLPKVARVAHKTGEIST-VAHDAGVVYLPKRKPYVLVILTEW -DPA-VAGRSRTIAAISHTIYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Aneurinibacillus thermoaerophilus TaxID=143495 RepID=A0A1G7Y4A6_ANETH --qKLRRDVERIVSQVDGKVSVAIE-TDEGHIL--INANDPLPSASLIKIPIMIAAYRQAQ -EGKLNLFSEYSFLPEDRVGGMGVLSHLSPELLTLKDLISLMIMISDNTATNMVIRNV-GM -DTVNQLAADLNCGQTVLVRMMMDH-EAVKRGKDNMTSASDIVRFLKEIVEGSILNEENKK -AVYDTLLNQQF-HTKLPAGFSLHATLAHKTGELP-GTEHDAGIFCFNGK-YAYVAVLTTE -LS-DNASGQRVIAQVGKLVFDY- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus saganii TaxID=2303992 RepID=A0A372LRU5_9BACI ----LENAILSEIDKCTGRVGLYLEM--EAGKI-EYNSEEAFRSASLIKVPILIEGYRQKE -TGRIHLNQPVTVQRRDKVGGSGVLQALSEKSMTLKDIMTLMIIVSDNTATNVMIDLL-GM -GPINHSIKELGLTKTVLERKMMDFQAA-EQGKDNLTCAADMVLCLKAIHNAEFVSEDNSK -EMLEIMEKQQF-LDKLPGMMDDKAVVAGKTGSLK-GIEHDCSVIRYHEK--VAYAAVLTD -GLQSKEDGRRTITNIGKHIFDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora rhizosphaerae TaxID=568872 RepID=A0A1C6SK00_9ACTN -------QLARVAAATNNRAGVAVRDLSSHQQI-AVNGAFRPKAASVIKLWILVELLRRVD -CRQLSLDRAVRVTRDDVVGGTGKLKSEAPQVVTTSRLAEYMIEYSDNTAANVLIDQLGGF -APVNALIDSMNQRETVLAHKLFDGAA--DRGGENYTSPDDVVSLLGAVWDARILTESSRD -LMIGFMRKQTR-NSKIPAALPPGTPLAHKTGDDID-ASHDVGYCLTPGA-ETAVAFLTAG -PSR---TGSETVRQLARTVHD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora orduensis TaxID=1420891 RepID=A0A5C4QUZ6_9ACTN --------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVSLDEGVLVTPADVVGGTGQLQFETPQVVTLHRLARYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus vireti LMG 21834 TaxID=1131730 RepID=W1SCH9_9BACI ----LEEKLKGEITCFQGRIGIAVEI--ANKRI-SLNSMEVFPSASVIKVPILIEGLRQAE -TGKINLNELTTIDK--RVGGSGVLQALSAKVMTIKDLMTLMITVSDNTTTNLLIDLL-GM -DSINSTIEKLSMEHTKLSRKMMDFE-AIEQGYNNFTSPSDMIKCLKVINEGDFLSEESRK -LAVEIMHYQQF-HDKLTAMMDDLVFAASKTGGLPN-VEHDCAILKYGGKT--AYAVVLTD -QLDNHFAAKHLISKIGKHLYDH- ->[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=A0A542EYW7_9ACTN --------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130ECBE6 -------------AALSGKIGCYYKNLVTGETC-TWHGDIPVIAASVIKLYVMTEAFAQIE -AGKLAMDQEITVHRKDCVPSCGVLTYHDDVKLQVIDLITLMIIVSDNTATNVLIDLL-GI -DNINARIRALGFEKTILNRKLFDAEKA-KLGLHNYITAEEVGALLEMMYRGTLVSEAASA -RMISIMKDQQL-NHKIPYLIPQAPQIAHKTGEDDN-TTHDAAIIFS--REPFILCICSND -TDV--TKLEPAMGRIAKR----- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_3_65_5 TaxID=1803450 RepID=A0A1Q7N1J2_9BACT --qRLQASIERTTRSISAAWGVYVKSLETGEEI-ALDADRQMETMSTIKIPLMVEAFEQIK -AGTFKLTDKYTFAQGDSQPGTGTIQRLDPGAMTVKDLLTMMIIVSDNTATEVLYRMVGGP -DAVTRRMDALGLTKTRAMNIPSKWFARDGKNPFGLSTPREMGRLLEMMERGTLVDKASSE -LMLQMMRGQLY-RTRIPRYVT-GYRIPHKTGDFLPYVGDDVGMLEAQGK-TIIVSIFTGN -HFGSGEALENAIGLVAKDVADYf ->[subseq from] serine hydrolase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI000248CF35 --nQLEATIREAASSVEGKVGIAV-DTAEGQIH--IYADEPFPSASLIKIPILLEAYRQAQ -EGRLDLHQPYAVPSGERVGGTGVIHQLSGTLLTLQDLMALMIIVSDNTATNMIIDLI-GM -ETVNKLSAGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVDGSTLKQEAKD -AALQLLRNQQF-NAKLPARMIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD -LV-DNLPAQQVISTIGKAVFDY- ->[subseq from] Uncharacterized protein n=1 Tax=Eggerthellaceae bacterium TaxID=1972561 RepID=A0A3C1DEL3_9ACTN ----LESDMQAIVEASGVPVGAAVVDLPTATRA-DYQGNLSLPAASMIKLLIAHAFLEGSK -TDPAGLDDVYTLQSSDIVGGTGTLGGLGAGAVTYRELVSRMIDVSDNTAANVLIDAVGGM -EAVNADARKLGLVGTELNRYMMDTD-ALARGIDNYTSASDCAKLLEMIYKGSFVDLASSQ -LMLQALEQQQD-EGGISAGLGSNVLFAHKTGSLSN-ARHDGGIVEG--EHPYVIVVLCGG -DGFYLDGANAAMRNIASAV---- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9YPK4_9BACT --qKMVTAIERVDRDLSGVMAVGVLDLTSGRQY-LLHGDEILPQASSIKIAVLAELYHQEQ -SGKQRLNDLYTVRGEDLVPDSDIMLGLTPGVLTNRDLATMMVAVSDNSATNALIERL-GM -ENVNATLRSLGLHDTLLRRKMMDIKAA-QQGRENVSTPREMMTLLAEIYRHKLFDKALTD -DFFKVLSGNA-KDSKFVPVIPEGVVIADKPGELE-AVRTDSGIIFTSNR-PFVLSVMTAY -LR-DEHEGDKAIGEVARAAFEYf ->[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Pediococcus acidilactici 7_4 TaxID=563194 RepID=D2EGV4_PEDAC ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV-DFN-DQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. HMA12 TaxID=2050894 RepID=UPI000CEA4873 --kKLETQIKQLIQGFQGEIGVYVHNLKKHKEV-NIGADNIFPTASVVKIPILVGVFDKIE -KGQLQLDQELIYRENQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINTLMADLQLQHTRVNSQTEGRKADWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD -RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN -NQGKTNAAEVLTRKLSKLLWDYy ->[subseq from] Beta-lactamase CARB-6 n=1 Tax=Paludisphaera borealis TaxID=1387353 RepID=A0A1U7CMN5_9BACT --kTLAQRIEPLVKAHKGKVAVAVKNLKTGESY-VYHADDVMPTASLIKFPVMIEAYRQAA -AGRINLDSTIKLHKADKVPGSGILTDHFSDGFALRDAVRLMIKFSDNTATNLVLDAI-GM -GATAETMVKLGCPDTKIHSKVYRRDTRSKLYGLGSTTAAQMIRLCEELKAGRLVDPKASA -AMYEHLATCDD-KDKFPRFLPEGAKIAFKTGSVD-ASRTAAGLIECPAG-SVALCVLTTD -NEDQDNAGNLICAKIAREVFDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter ruber TaxID=990371 RepID=A0A1G9XZ66_9SPHI --qKTENDLKEIIGSSPSLTGLMAIDLTSGEII-GINSDIVFTQASAIKIPILMEVYKQAH -EKKFALSDIKPLVASNIVAGSGILNAMTDPVLSIRNYCMLMIGLSDNSATNTLIELV-GM -KNINSTMQSLGFPNTKVQRKMIDQPAS-LRNEENLSTPAEAARIMKLLHEGKFIDKTSSE -EILSILKKNPIENSKLAGGLPSNVKLAFKPGGMG-GVSTEWGIVYLSNS-PYAIAVMENY -KT--SATPSDIIAAISKRVFDYf ->[subseq from] serine hydrolase n=1 Tax=Emticicia sp. MM TaxID=1839755 RepID=UPI0009EEF11F ---------------SGIKVTMAVENMEGKSYF-KHRIDVKVPSASVIKVPILMSLMEKVQ -ANELSLSEEHSLTNAEKAGGEGIFMSAAEGEFTIRKIAEEMIRTSDNTATNILIRKI-GM -ETINQNLTKWGTTKTRLNRVMMDIEA-VKQGRENYVNALEINALLRMIYDRKVANPILCD -EMIGMLKNCED-TTTIPSQLPKDLAIAHKTGTLAY-VRGDAAIVFTT--QPFVISIFVEG -FDKE-ATAEKIIGDLAKICWE-- ->[subseq from] serine hydrolase n=1 Tax=Fictibacillus sp. FJAT-27399 TaxID=1729689 RepID=UPI000785F886 --nELNNRVNDIISGQNGDYAYWIE-TEDG-HI-EYQADEVFPAASLIKIPILIEAFRQTE -AGQIDLASRISLKQEVRVGGAGVLQLFSDESVTVADILTLMITVSDNMAANIMIEKT-GM -ERINDLLAELGCSQTVLQRKLMDFEA-VKQGKNNYTSARDVILQLKEIDRGGRLKDKSSQ -TILHILQNQQF-RYKLPAYMDEKITIANKTGELD-GVEHDAGIFTFKRE-KLFAAVLTKN -LP-SEAEGRQALALIGKALND-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium tuberculosis TaxID=1773 RepID=A0A655EGI6_MYCTX ------------------------------------------------------------- ----------------------------------------------------------GGT -AAFTGYLRSLGDTVSRLDAEEPELNRDPPGDERDTTTPHAIALVLQQLVLGNALPPDKRA -LLTDWMARNTTGAKRIRAGFPADWKVIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDR -AGYDAEPREALLAEAATCVA--- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SYI8_9BACT -------NLADLENKYNAVIGVYAVDMENGKKI-CYKPDTRFSYCSTHKVFTAAELLRQKN ---TSDLNEIRKFSAEDILSYAPITKDHVADGMTLAEICSASLRWSDNTAANLILQEIGGV -ENFKVALKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKEK ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A353B773_9PLAN -------QLESLCEAHDGDVSVAVQIFGSCGRF-ERAAERTQPTASLIKLPVMMEYYRQVD -AGQLSPTQRIELTEADKVPGSGILTEHFSAGLPLEDIVRLMIRYSDNTATNMVLDAI-GL -ESTAATMKALGWPETQIHSQVYRRSTRSQKYGLGSTTASDMLEILVALHLGDLTSAESRQ -KMLAHLSSCED-DTKLGRYLPTGATLANKTGAVSR-VRTDAGIIRYRDHT-ILAVVLTSN -NATDRNAAERLCGRIGQVL---- ->[subseq from] Beta-lactamase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=A0A6D2GJR6_STAAU ----HAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLN-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus fluminis TaxID=511487 RepID=A0A3M8DNS2_9BACL --dQLKETIIDLTAKAGGTWGVFVEDLDTGKSL-AHNEGELFLAESVIKVPIMAAVFAAAE -EKRFNLSDTMTLRREDMVGGSGFLQHMTPGILPIYDLITLMIVQSDNMATNMLVDLV-GA -DAINQTMRETGMKESHFFNKCCVYPV--KREGLNEITAADVNALLKTLATGSYISYHACQ -QMIEIMKKQQV-RNGLPAYLPESWEMAHKPGWDT-GRQHDAGILFAGKR-SVSITVLSKD -IEP--FSALDTLAKIGRSVYAY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI001183428D ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLK-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Clostridium tetanomorphum TaxID=1553 RepID=A0A037Z5V9_CLOTT ---KMIDKIKEEIDKFKGVCGVVIKNENTKEYY-AYNEEIVFPSASIIKLSILLELFKRIE -KGEFNLEDSVTIREEDKTGGFGVLKELDCNVLTIKDIATLMIILSDNVATNKLINIL-NM -ESINSTAKELGMKSTILGRKMMDGDA-KKRGLDNYTSPKDTLTILEAYLNPSKLSPENRE -TILDILKKQQC-NNKLPFLMPKNVSFAHKTGDLP-GVEHDAGILFSQAGT-IVIVVLTKD -LE-DNAHGVQFNNSIGKIVTKY- ->[subseq from] Uncharacterized protein n=1 Tax=Mycobacterium gordonae TaxID=1778 RepID=A0A1A3L0Q7_MYCGO -----ERQVERRILAAPADVAVLFRLLGGEAEW-SYQPDVTFHAASTMKVPVMIELFHQAH -QGQLTLDDPLLIHNESLVDGSAFYYSSEGQTRTLRQLCELMITISSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR -QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYG--SQPFVLVILVRG -MAN-SKDSSALMADITRAFYR-- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus pakistanensis TaxID=759811 RepID=A0A5Q2NCB0_9BACI -------AIQRMLEEAPYNVHLFIKDPNTNHYFiQEKLHAVFSSASLIKVPILLGVLRYLE -RYHQDVHQEIRIAPEEWVDYSVISEQRIER-STIYELLVWMIITSDNAATNVLIDFI-GM -EFLNHYFRQIGLRQTKLQRKMMDFEK-LERGIDNLTSANDMAHLFSRIYQQDLLPKQFSK -LTIDILSRQRV-HESLKRYLVDDVKMAHKTGGLET-VEHDVGIVYNGSN-DYLIGVFITE -VT-NNEYAKQLIGRISKSAYEH- ->[subseq from] serine hydrolase n=1 Tax=Bacillales TaxID=1385 RepID=UPI000491383A -------SIGKLMEETGGQWGIYLEDVRTGERL-GFAEHQRFYAASLIKVPIMTAVFAEAY -AGRLALSDKLRLRREDQVGGDGVLQHLTPGTLTVYDAVTLMIIQSDNTATNMLIDLV-GT -DAIRAAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRCLATGKAISYNSCL -HMINILKRQQH-RDRIPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VTICTL--S -RDVDAKAAGEMMGRIGRMVYDLy ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGT-18 TaxID=2493087 RepID=UPI000F62A000 ---ALEPRLRAIEAALGAGIGVYVLHMDRDESY-GYRAGEPWYLASGVKVPVAIAVLREVE -RGTLALDTPVVLRADDYVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL -AAVNRVAAELVDARLRIT------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGT-18 TaxID=2493087 RepID=UPI000F62A000 ------------------------------------------------------------- ----------------------------------------------------------AGP -ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG -WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG -TG--TAAGEHALQRIAAAIT--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Cyanobacteria bacterium J069 TaxID=2420337 RepID=A0A3M1PQA1_9CYAN ----LTTTLQSLVAQSGLVSGVFVVDLDTGDYV-DLNGSLAFPAASTIKTPILVAFLQDVD -RQRVRLDESLTLQAGDLTGGSGEIQMELGSQFSALDIATKMITISDNTATNMVIHKLGGL -AALNGRFRDWGMSHTVLNNLLADLEGT------NTTSARDLSLLLTAVSQGDLLSLRSRD -RLIDIMRSTVN-NNLLAATLGPDAKIAHKTGNIDS------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZP28_9BACT --qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK -AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTVKDLITLMVIVSDNTATEVLYRMVGGI -DAVNRRMDAMGLKSTRAMSLPTTWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD -LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN -HFGSGEALENAIGLVAKEVADYy ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus timonensis TaxID=2086577 RepID=UPI000D0F2F77 -----------------------VKETRNNTLLiCERFNEEFSSASLIKVPILMAVLHFVE -QNHRLLQESIRVNDENKVDFSIITEQNLRV-STLYELLVWMIISSDNTATNVLIDYI-GM -NELNNYFQLMGLTQTRLQRKMMDVKQM-EQGVDNMTSARDMEHLFSRIYRQDLLSTKYSE -LAINILCRQRI-QDCLKRYIEDDVRVAHKTGSLDT-VIHDVGIVFNDVS-DYLIGIFITE -VK-DTDNAKQLIGRISKEVYHH- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura rayongensis TaxID=1429076 RepID=UPI0013527251 --------VEDAFRAAGVTGWLHAEDVDTGRRV-GVRADEPVVLASVFKVPLLVAFFRRAA -AGLLDPAERVTLRPGDRAEGPTGTSILLDDVLSLRDLAALMITVSDNAAADVLYDRVGGA -DAVNADLAALGLTATRITGNGRELFAALNPVLTSRSTPREMAALLGLVWRDEAAPPAACA -QMRRMFGLQVW-PHRLSAGFPDDVRVGGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRA -ARAALPQADAVIGAAARLAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. IC_126 TaxID=2547400 RepID=A0A4R0PT24_9PSED ------------------------------------------------------------- ------------------------------------------------------------- -----AVANALSLSESELKASMEQAYERYYARNLNSSTLEAYGTLLEKLVEGDLLSESSRD -LLFKDMKLDRYDAYRLEAGLPSDVPFIQKTGTQLE-RACHVGVIEPEKQEKTVIIVACAE -ALDEAKEAGAAFERVGEAIT--- ->[subseq from] Serine hydrolase n=1 Tax=Burkholderiaceae bacterium TaxID=2030806 RepID=A0A5C7PV72_9BURK ----------RIGEDAASAVAVAVYDFEHHTTW-SINPARWFHAASTIKVPVLLGVYDAIE -QHRFDPISRVHVRNRSVVDGRPYRQAAIGRMLTVHELAEHMIVTSSNLATNLLLDLV-GI -EAARASLARLHVSGIDLRRGVED-ESAWEAGINNRVTAAGLCETLRLVEEGKAISADASK -AMLDILHQQRF-RSGIPAGLPEDARVAHKTGEIST-VAHDAGIVYLDGRDAYVVVILTEW -AP-DVNARQETIARISRAVYEY- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. 160415 TaxID=2495887 RepID=UPI00110C4F75 --------FETLFRVAGVTGWLYAADIDSGREV-GHGADEPLPTASMFKVPLLVEFCRQAD -AGLLDPTSRVTVTAGDRVTPTGISAMLDDVTISLRDLAYLMIAVSDNSSADMLLGRV-GI -DAVNAMLAKYGLDSTRVTQSCRELNDSLDPARANRSTPREMARLFGLIWRDEAASRASCA -WMRAVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Gemmobacter nectariphilus TaxID=220343 RepID=UPI00040C68AE --------------AGGARIGLALS-LDGKMLF-AHRADERFISASVVKIAIMAEVFRAAD -AGVLRLDQPVTVTADMMAPGSGIMNHLAPGYLQLRDVLYLMMSISDNTATNILIDMA-GM -DRINATMQALGMSGSVLGRKMRGR-RAIAGEAENIAVPADYDRLIGAIVNGTAASAPACA -EMMDLLRGQQN-ERRLARFLPKGADWGSKTGTVE-GVVNDAGFLRTAKGT-AVLSMFTEG -FE-RMVDAEAVLGDLAQAAF--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus sp. LEMMJ03 TaxID=2595056 RepID=A0A553KNI9_9BACL -------SIGKLMEETGGQWGIYLEDVRTGERL-GFAEHQRFYAASLIKVPIMTAVFAEAY -AGRLALSDKLRLRREDQVGGDGVLQHLTPGTLTVYDAVTLMIIQSDNTATNMLIDLV-GT -DAIRAAMSRTEMVNSSFYNKLMIVPAEPEG--YNEVTAADMGSHFRCLATGKAISYNSCL -HMINILKRQQH-RDRIPCRLPPKWELANKTGTVTN-ITHDAGILYVGGHA-VTICTL--S -RDVDAKAAGEMMGRIGRMVYDLy ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA15(2017) TaxID=1932111 RepID=A0A1Q9Y500_9PSED ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALKMKPDQLERDLDEAYQRYYETGLNSATLVAYGQLFGKLANGELLSEASTR -LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGEDALVILACAEA -LDED-AEAGKLFEEVGEAIQ--- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter latericius TaxID=86104 RepID=UPI00041DF09C --eNLKQTIQAQIDSIDGTVAIAFYNLSAPKDSlYINVDEKFHAASTMKVPVMIELFKQAN -EGKINLNDSIILKNESIVDGSLYSYQQIDTKVALKDLMYSMITISSNLATNVLIELV-DA -KKVTASMRDLGAEKIEVLRGVEDLK-AYEKGLSNSTTARDLMSIMKSIANYSAGNKKDCE -AMIAILKDQQH-KEVIPFYLPKEVKVAHKIGSIT-GVHHDAGIVYLPDGRAYVLVLLSKN -LK-DFDKGTDQLARISKTLYNY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. ALFpr18c TaxID=1458665 RepID=UPI00124AF5DC --------------------GATVRDLSGDQQI-AVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDEGVLVTPADVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNIAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sienata TaxID=248552 RepID=UPI0007A50B66 -----AERIRAVFADAGCTGRLHARRCDSAAEV-SIGGAERVVTASVYKLPLLLAYCRAVD -AGRLDPLARLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL -AAIHELLESLGLEQTRLVGGTADIQRAYDPAYTSATTPEEMTRLLAALWRGEVLSGEQTD -FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus psychrotolerans TaxID=126156 RepID=A0A1I6ACJ5_9BACI --eELVSEVQKLVEQSKGTWGIVLEDLNSGEKW-FHNEQELFYAASVIKVPIMASVYRAVD -RGDLSLMDLIILNEKEYVGGSGVLQHFTPGLLPLQDVIMLMIIQSDNTATNLLIDLV-GV -DDIQNSMKEAGMVYSTFYNKLMLSKSNPKG--ANRIAAADIAILLHKMAMGDLVSGKASR -QMVEVMKKQQV-RDCLPERLPSPWELANKTGWIP-GTRHDAGIFYVGNRK-LIATVLSKD -ED--DLLSKRILAQIGEEIYKY- ->[subseq from] Serine hydrolase n=1 Tax=Ilyomonas limi TaxID=2575867 RepID=A0A4U3L5F7_9BACT --kKLRANIQSLLQGFNGDVGVYVHDLEKGKTV-AINADSIFPTASMIKIPILIGTMHKIE -DSELQYHQELIYSDSLLYPGVDILGSFKDTEIELSKIMMLMLTMSDNTASLWLQSLAGGG -QRINAYLDSLGMKVTRVNSRTPGRKDNQSKYGWGQTSPREMATLMEMIVKGQIISKAASD -RMLRLLSRNYW-DEEAVSQVPAGVFVASKNGAVDE-SRSEVMYVNGKHC-RYIFCICTNN -NKAANNEAWVLTRKLSKLLWEYy ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=A0A562JIK2_9BACI ---KLKAEILELANCCEGRVGVYIQS--EEGII-EENCRKAFSSASLIKVPILLAGLSQAE -TGLLQLEEEVQINNAVRVGGSGVLQSMSKGLMKVIDLMTLMIIVSDNTATNLVIDLI-GK -ENINGYMKNIGLKNTELNRKMMDFE-ALKKGVDNTTTARDMAFCLEGLAERSILSVENKD -LARRILNGQQYKNKLANTVDLEKVQVANKTGELP-GVEHDCGIFTGNGR-TVYTAVLVDQ -LKN-QAAGRDVLSFIGNRIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. B29 TaxID=1933220 RepID=A0A1P8EAL9_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -VAINKLMSDLQLAHTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTRIRQGKVVSQKSSD -QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEVLTRKLSKLLWDYy ->[subseq from] serine hydrolase n=1 Tax=Halomonas socia TaxID=1081866 RepID=UPI0013D0AE94 ------------------------------------------------------------- ------------------------------------------------------------- ----AAFAERLGVAPGELAVDYDAAFDAYEDSALNGGSLVAFGDLLATLARGDGLSAASRE -ALLAVMQRTRSGEARLKAGFGDDVVFAHKTGTQHR-RSCDAGIAQRGSGRQVAVVACTRG -PLA-VAIHERLLAEVGAAI---- ->[subseq from] serine hydrolase n=1 Tax=Litoribacter sp. XAAS-A1 TaxID=2598460 RepID=UPI00117D5D8B ---TLKAEITEELSSVEGDFAVAFRLLGSNKEI-LINEKENFHAASTMKTPVMIEVYKQAA -AGIFQLSDSITVHNESIVDGSAYSYDRIDKKATIYDITYAMIIKSSNLATNILIDLV-GA -EETTGSMRDIGAPDIMVCRGVEDQK-AFDQGLNNTTTAYDLMVIMEAIATGNAVDEEADA -QMFDILADQYF-KDLIPAHLPEDVVVAHKTGFIT-GVQHDSGIIRLPDGRQYALVLLSKN -LG-DRDEGKRVMANVSKMIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. S3 TaxID=486398 RepID=A0A513RE21_9BACI ---RLMEKIEEELRGLSGRAGLAIEM--EGKCI-DINSKEVFQSASLIKVPILIEGLRQSD -RGTLNVNQLVSITS--PVGGSGVLQVLSRDALTLMDLMTLMITVSDNTATNILIDEL-GM -EAINRSMVKMGLQHTVLNRKMMDFQ-ALEQGRDNYTSPADMLTCLKVIMEGSYLTEESQA -AALRMMKFQQF-QDRLPGMMDDRVMAANKTGSLPH-VVHDCAIITYKGKT-AYAAVLLDR -LD-DEFTGNQIISRIGKHIYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8CEH4_9BACT --qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK -AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTVKDLITLMVIVSDNTATEVLYRMVGGI -DAVNRRMDAMGLKSTRAMSLPTAWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD -LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN -HFGSGEALENAIGLVAKEVADYy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9C597_9BACT -----------------------------------------------------MELLRQAQ -AGRLKLDDRVAIKQVQMVGGSGVLQFFGDASISLRDLAVLMIVLSDNTATNILIDQV-GM -ANVNDTLAHLGLAQTRLQRRMIDTAAQ-RAGRENLSTPREMTTLLELLHGGKVLDASHTA -ALLEILKYPKENASPLRNGLPDGIALANKGGSLP-GVRCDSGIVLLPDR-PYVISVMTTY -GH-DSHAAERAISEVSRRVFEYf ->[subseq from] serine hydrolase n=1 Tax=Steroidobacter cummioxidans TaxID=1803913 RepID=UPI000E316757 ----LSRLLEAELSRLPTRSGIYVKHLSTGETA-SVRGTDEFESASTIKLATMVLAYRLAD -ERKLDLNQRYVIKQADYRGGSGIFRHHDPGMPTLRDLITQMVITSDNTATDIMIAKVGGK -EAVNRFLRDAGYQVLRQNNTTLEFFRAVWNDKANWATPQEMGRLLESIELGTAASEQSCE -EMKRILLAQQSGVIKLPHYLT--VPIAHKTGETGT-VTNDVGMIYARSGT-IIISFYNVE -LSGPRAETEDGMGRVARTVVDYf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. TaxID=341027 RepID=A0A3C0ZFD9_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD -QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEALTRKLSKLLWDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=A0A1I2FBM6_9BURK ------------------AFGVYVRDLDTGDAL-SFHGAERWYLASSVKVPVAIAVLRGVE -RGAFTLDTPLTLREADYVDGAGPTKRQAAGTLTVRWLLEQMIVFSDNTASDMLIELV-GL -PAVNAVAQEAAPGGLERITTLADVRRAYYATGLNSGRLDAYGELLAQLAQGRLLNPAHTR -YLLGVMERVQTGPQRIKAGLPAGVTFAHKTGTQR-ARTCDSGLITRPADAVRAIVVACTR -GEPSTTRSDRTLRQVGIAICQ-- ->[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537KGT8_9BACT --------------PVGAAVGLYYRSLAGSDSL-LVNAHARFHAASTMKVPVMIQLFRDAD -AGRLSLADSLRVHADSLVDGSTFLYESIGRRVSVRHLLELMETVSSNLATDVLVERV-DA -KRANATAHALGADSIVVLRGVEDGK-AYRAGLNNTTTARDLGVLLTAIAQHRAASPASCD -SMLAILGRQHF-TEGIPAGLPAGARVYHKTGWIEGVVYHDAAIVEPPDGKRYVLVVTTGA -IKPD-SAAYRLVADLSRLVYD-- ->[subseq from] serine hydrolase n=1 Tax=Psychrobacillus psychrotolerans TaxID=126156 RepID=UPI000B876727 ---ELVSEVQKLVEQSKGTWGIVLEDLNSGEKW-FHNEQELFYAASVIKVPIMASVYRAVD -RGDLSLMDLIILNEKEYVGGSGVLQHFTPGLLPLQDVIMLMIIQSDNTATNLLIDLV-GV -DDIQNSMKEAGMVYSTFYNKLMLSKSNPKG--ANRIAAADIAILLHKMAMGDLVSGKASR -QMVEVMKKQQV-RDCLPERLPSPWELANKTGWIP-GTRHDAGIFYVGNRK-LIATVLSKD -ED--DLLSKRILAQIGEEIYKY- ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Planctomyces sp. SH-PL62 TaxID=1636152 RepID=A0A142YJ03_9PLAN ---DLAGRIEMLTKAHKGKAAVALKNLRTGESY-ALNADAPMPTASLIKFPVMIEAYRQAA -AGKIDLAAPVTLTKKDKVPGSGILTDHFSDGFPLLDAVHLMITFSDNTATNLVLDAV-GI -GSTAATMEAMGFPNTKIHSKVYRRDTRSKVYGLGSTTAADMIRLFEALHARKLVDEKASE -AMWNHLLTCDD-KAKFPRFLPPGTKLAFKTGSVDE-SRTCAGVIETRGG-PVALCVLTTD -NETDDNAGNLLCARIAREVYDHf ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA15(2017) TaxID=1932111 RepID=UPI0009F85C3D ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALKMKPDQLERDLDEAYQRYYETGLNSATLVAYGQLFGKLANGELLSEASTR -LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGEDALVILACAEA -LDED-AEAGKLFEEVGEAIQ--- ->[subseq from] serine hydrolase n=1 Tax=Ornithinibacillus sp. L9 TaxID=2678566 RepID=UPI0012D8A7AF --eQLAEKISQKIEQVGGTWGIALEDLDTGEVW-LRNSDETFYAASIIKVPIMIAVFHAHE -YEGLSLSETIKLRSEDIVGGCGVLQHLTPGILSLHDLTTLMIIQSDNTATNMLIDVL-GK -EQIQQVMKDYGLNKSEFHHKLMTVPV--EKEGSNCITAFEMTSLLKKIVTGKVVSFHACE -KMIEVLMRQQI-TNGLPAKLPKSWMFAHKTGNVHQ-TRHEIGIFYIGKRK-MIVSVLAKG -ID--DRILQEAFTEIG------- ->[subseq from] Serine hydrolase n=1 Tax=Thalassobius sp. TaxID=1979401 RepID=A0A2E9G4R8_9RHOB -----------------------------QDSI-LINATEEFHAASTMKTPVMFEVFKQVE -AGKLDLSDSILIKNNSIVDSSEFVYQVIGDSLPLYDVMYKMIIKSSNLGTNLIIEKV-GA -KNVTQTMRDLGAPYIQVLRGVEDLKA-FEKGMSNTTTAYDMMVLYEKIANSEVLSKESNE -KMIEILLDQYY-NEMIPAKLPTDVKVAHKTGSIT-GVRHDAGIVMLPDGKKYVLVLLSKN -LENP-DASIEKMAEVSGKIYQY- ->[subseq from] serine hydrolase n=1 Tax=Laceyella tengchongensis TaxID=574699 RepID=UPI0012B906B1 ----LIQNLEHWKGRAVGNWGVWIEDLTSATTW-AWNETKSFYAASIIKVPIMVAVYKQAF -LGRLALADEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT -ETIRETMDELGMRQSTFHNKLMIVPAAPAG--LNMITAADVARCFRHIAQGKVVSQHASR -QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTR-TLHDAGILFTKSRA-VVMVALSEE -CE--YEQAQQQMKQLARLVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4Q9B6_9FIRM -----LAEIEEIARGFSGRLGVWACRVDGGEPV-AYGAEEPFPTASTIKVPILYEVFRQAG -EGRFRLEDPLPLTRENQVPGSGVLKDLTPGILPVRDYCTLMITVSDNTATNVLLDLV-GV -EAVTRSMAAIGLHRTRLYRKIFQGS-----GPLAESTPADLGRLLLGLARGEWLTPGACA -EMLGMLYRQQH-KEMLTRYIDDYVRVASKSGWSDD-VRADVGLIETPSV-RYVVAIMSKG -CRPPDPGGAIVLALLSRALYDHf ->[subseq from] Beta-lactamase n=2 Tax=Candidatus Sulfopaludibacter sp. SbA4 TaxID=2043165 RepID=A0A2U3LIV9_9BACT ---PLQQAVRARIGDFQGMVSLYAKNLDTGAAF-GIRESEPVRTASTIKVPIMLAVFDAVS -RGQAKWSEPLTVTAAEQVSGTGVLGEMSDGDLPLRDVVQLMIVLSDNTATNLVLERF-TA -DAVNAYLDKLGIRTTRVMRKIRGDGSENEKYGIGMSTPRDMATILEKLERGEIVSRDASR -EMIAILKRCQD-GTGIRRRMG-GLAVANKTGSLD-ALRSDVGIVYSKGG-RIAMAITVDG -MPTPDNTGSVLIADLAKILVD-- ->[subseq from] Beta-lactamase n=2 Tax=Cyclobacterium marinum TaxID=104 RepID=G0J738_CYCMS ---SAQQSLKAYLKTIDNKVSLYIIQNKQGKILsMSNSDKIIPSASIIKVPLLIYFMQKAS -EGTFSLQDHYHLKDEDKVGGSGELQFKPAGIVTYEYLAKEMIRVSDNTATNIIIKKL-GL -KAFQKWMKENDYSATQLNRFMMDFD-AIEKGKQNYCSSKEINRLLLALYNGDLLAENPSL -KVIEWLKNCED-NTGLPHLLPDRVAIAHKTGTLDY-VRGDAGIIFGE--NPIFITVLVEN -FS-EIAEADSIISTIGRLAYLEy ->[subseq from] Serine hydrolase n=1 Tax=Microbispora bryophytorum TaxID=1460882 RepID=A0A544XUK8_9ACTN ---------ERVFRSAGVTGWLHAVDIDGGREV-GLRADEPVVLASVFKVPLLLELHRQAE -RGLLDLTERVGVPAADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNTLLDGLGLTATRVVQDCREMLTALDPAWGNRSTPREMTRLLAAIWRDEAAGPASCA -AIRRLMALQVW-PHRLASGFPDEVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LSQNQPRADAAIGAAARMAIDQ- ->[subseq from] Serine hydrolase n=1 Tax=Opitutae bacterium TaxID=2026771 RepID=A0A2G4HJJ2_9BACT ----LEAQLRALIVSFKGTVTLHARHLESGAEV-GIEPDKPVRTASTIKLPIACAVAAQVA -AGQARWDERLTVADASKVSGSGVLSEFSAGEISLRDAVRLMIVVSDNTATNLVLDRI-GA -DAVNDYMDSLGLRRTRALRKIRGDGTDNQRFGTGSSTPREMTRLLGMLADGKVVDEAASR -DLLDTLKRQQY-KDGIGRQSG-SLHVASKSGSLD-ALRSDVGIVWTPQGR-IAVAITVDD -MPSPDNAGNLLISRLSQ------ ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium jeungdonense TaxID=708087 RepID=UPI0013D17C02 -----------------------LIQDETGKLLaQRQPNKKVPSASIIKIPILLTLLEAVD -KGELALDSVHVLKSQDKVGGAGELQFVPDGTLTFRFLAREMIRISDNSATNILIEQL-GM -NRIQDWLSIRGFTDTQLNRKMMDFD-AIERGHQNYTSPTEINRILLMLVQKDKLPANSIA -EALVILKSCED-NETLTAFLPTKLEVAHKTGTLDY-VRGDAGIIF--GRRPLILSVFVEN -FD-DISEAEKIIAEIGKLAYETy ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TTU2014-066ASC TaxID=1729723 RepID=A0A0T6VPK7_9PSED ---GLEEELRRIDDEAPGDLGVYIKHLGDDAQL-RYNAERFWYLGSAVKVPIAVALLQGID -DGEHSLDERLSLQADDKVDGSGDLVWQDEGVYSLRDLLTEMLIESDNTAANMLIRLV-GE -DELNQRTRKMGGDGFERITTFTQVRRRYYARKLNSSTLVAYGALLERLVRGELLSEASRD -VLYADMKIDSYDNYRLEAGLPEDVPFIHKTGTQLE-RACHVGVIEPRDEARAIVVAACAE -GLDEGKEAGQLFERVGQAIT--- ->[subseq from] Uncharacterized protein n=2 Tax=Hungatella hathewayi TaxID=154046 RepID=D3A9C2_9CLOT -----ELNVADQIKALPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE -EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRTASE -AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETALWLY--- ->[subseq from] serine hydrolase n=1 Tax=Fulvivirga lutimaris TaxID=1819566 RepID=UPI0012BD00FA --eQLERTVMAQIDSIDGTVAVAFYSLTEPKDSlYINIGEKFHAASTMKVPVIIELFKQAA -EGKLDLNDSILLKNESIVDGSLYSYQQINTKVALKDLMYSMITVSSNLATNVLIELV-DA -KKVTATMRDLGAKDIEVLRGVEDIK-AYDQGLSNSTTARDLMVILESIANNRAGSQKDCE -VMITILKDQQF-NDIIPKYLPKEVTVAHKTGSIT-GVHHDAGIVYLPDGGAYVLVLLSKN -LN-DFNKGTEQLAKISKTFYD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Actinomadura sp. 5-2 TaxID=1926885 RepID=A0A2P4UQS9_9ACTN ---------EDAFRAAGVAGWLHAEDVDTGRSV-RVRADEPVVLASVFKVPLLVAFFRQAA -AGLLDPAERVTLRPGDRAEGPTGTSILLDDVLSLRDLAALMITVSDNAAADALYDRVGGA -DAVNAVLAGLGLTATRITGDARELFAALNPVLTSRSTPREMAALLGLVWRDEAAPPAACA -QMRRMFGLQVW-PHRLSAGFPDDVRVGGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRA -ARAALPQADAVIGAAARLAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Microbispora rosea TaxID=58117 RepID=A0A1N6TJE3_9ACTN ---------ERVFRSAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELQRQAE -RGLFDLTERVGVPAGDRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNALLDGLGLTATRVVQNCREMLTALDPAVGNRSTPREMTRLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -FGQNQPRADAAIGAAARMAIDQ- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea coxensis TaxID=404386 RepID=UPI00035D710A --------FEALFRVAGVTGWLHAADLDTGREI-GHGADEPLPIASMFKVPLLAELCRQAD -AGLLDPAERVTVPAGDRSSPTGISAMLDDVTMSLRDLAYLMIAVSDNASADVLLRRV-GR -EAVNAMLASYGLDVTRVRRSSQEINDAFDPAWGNTSTPREMARLSGLIWRDEIASAASCA -WMRGVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGGRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus panacihumi TaxID=497735 RepID=A0A3M8CRK3_9BACL ----LKKQLSQIVEDAKGTWGIVVEEVGQGICY-EHLPDQSFIAESVIKVPIMAAVFAAAW -QGEFSLEDRLVLRREDMVQGSGMLFALSPGLLSIRELATLMIIQSDNTATNILIDLV-GK -ERIDQTMRELGMKESRYVRKLMIYPADNPG--NNTITARDVTTVLSQLGAGRYLSAKACE -EMVAIMKKQQF-RNGLPSLLPTDWEIACKSGWDT-GRQHDAGLLYTQGR-CFAITALSQD -VE--AEEALHTLGSIGKAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI0005C5F2A8 ---GLEEELQRIDAESPGELGVYIKHLGDDAQL-RYNAERFWYLGSAVKVPIAVALLQGID -DGEHRLDEQLSLQTEDKVDGSGDLVWQDEGVYSLRDLLTEMLIESDNTAANMLIRLV-GE -DELNQRTRKMGGDGFERITTFTQVRRRYYARKLNSSTLVAYGALLERLVRGELLSEASRD -VLYADMKIDSYDNYRLEAGLPEDVPFIHKTGTQLE-RACHVGVIEPRDEARAIVVAACAE -GLEEGKEAGQLFERVGQAIT--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6I2Z5_9BACT --kKLEARVAETADRIDGVMGVAILDLTDGRIL-LHNADRVFPTASSIKIAILLELYRQDQ -KEKSQLDDNYTFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANILIDRV-GK -DNVNAMLHGLGLSKTMLRRKMIDIAAARRG-DENVATPQEMARLLEAIYKGKALSKQATA -EFIKQLSTKKG--SYIPRYLPESVQVANKPGELE-AVRTDSGIVFCS------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A651DFH0_HALSX ------------------------------------------------------------- ------------------------------------------------------------- ---AQALARTLGVTDTFAQPDYDGAFDAYEATGENVGTLSAFGDLLASLRGVQAVNAEQRQ -ALLDVMRRTSSGEQRLKAGMGKGISFAHKTGTQQR-RSCDAGIAERAAGAGAWVIVTCTR -GPLAVSAHERAMAGVGDAL---- ->[subseq from] Uncharacterized protein n=2 Tax=Sphingobium TaxID=165695 RepID=T0GJR1_9SPHN ---------------------------DEGWTV-SFNGGRMLPQQSVSKLWVAIAVMDAVD -HGALSLSDPVTVRRSDLTVHQPIRPLVTKAGTTIGKLLEMALTRSANSCNDVLLWKVGGP -EAIRAMLKRKRINDVGFGPGERKLQARYLANPYDGASANGVTLGLMLLKQGKLLSKSSTR -HLLSLMRASRTGPLRLRSGLRNGWTLAHKTGTGQTTGYNDVGILVSPEGHRYAVAVMIAS -TRAPIPARMRLMGDVTRAVIR-- ->[subseq from] Serine hydrolase n=2 Tax=Acidovorax sp. Leaf160 TaxID=1736280 RepID=A0A0Q5L797_9BURK ---ALQRELERAAAGGATPFGVYVRDLNTGESM-SFHASERWYLASSVKVPVAIAVLRGVE -RGAFTLDTPLTLRGSDYVDGAGPAKRPVGTALTVRWLLEQMIIYSDNTASDMLIGLV-GQ -PAVNAVAQEAVPGGLERITTLADVRRAYYATGLNSGRLDAYGELLAQLVEGRLLNPTHTR -YLLGVMERVKTGPQRIKAGLPSGTRFAHKTGTQR-ARTCDSGLVIVTPREARVIVVACTR -GEPSTARSDRTLRQVGIALC--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus firmus TaxID=1399 RepID=UPI001331B050 --hTLKAEILKLASCCEGRVAVYIHT-E-DGFI-EKDADAVFSSASLIKVPILLAGLSQAE -KGLLQLEEEVEVTASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI -EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMAYGLKALAVQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVKVAGKTGELP-GIEHDCAIFTHKRK-TVCAAVLVDG -LQN-QAAGKEVLSAIGSRI---- ->[subseq from] Uncharacterized protein n=1 Tax=Phenylobacterium hankyongense TaxID=1813876 RepID=A0A328AUW3_9CAUL -------LLQAELARFPSKSGIYVKDLATGEEA-AVRGDEHFESASTIKIAVMVLAFRLAD -AGKLDLNARYTLRPEDYRGGSGVLRYDFGATPTVRDLITQMIITSDNTATDIMIRKVGGP -AAVNDFLRGSGYVALKLNKTLLDHFRARQNDVEDTVTPVELGRMLEGIERETVASPAACE -EMKRMLRAQQSGARKIPHFLT--VPVAHKTGENT-GVTHDMGMIYARSGT-IVMVSLNTG -ATGLIADADDRIGELARLVVDYf ->[subseq from] serine hydrolase n=1 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=UPI0005626E60 -----EKIIQDLLHETPYKVHLFVKNPKNEQFLfSHQIGEAFSSASIIKVPILLAALAYFE -KYSLSLHSSLPISPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -EFLNDYFRQIGLQETLLQRKMMDVER-LAMGLDNFTSAWDMAHLFTRIYQQDLLAPPYNR -LVIDILNRQRA-HEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNSID-YLIGVFITN -VTEN-ELARQLIGRFSKVVYDH- ->[subseq from] serine hydrolase n=1 Tax=Pseudohongiella nitratireducens TaxID=1768907 RepID=UPI00083B99C4 ----LEAKVAEAEENIRLSIGVAGLATQEGRMT-FVGSPESYPPASTIKMLLIATLMQQVD -AGTLSLEDTATVEQSDIVGYGEIQNEPVPNEVTLGRLAELTVTISDNTATNVLVDVV-GY -EAMQALADELELETMQFGRKMFESP--MPPQKQNYINAEDTIQLLKQIYNDSFLTSQSRR -QIIAWMSAQTV-TTKIAAGVPEGMPIAHKTGENAS-VTHDLGYLLWPENE-VAVAIFAES -EVSDQAAVNPVVAAVAGIIYEH- ->[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XHA6_9ACTN --------------------GVTVRALSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVE -CGQVALDDGVLVTPEDVVGGTGQLQFETPQVVTLHRLARYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Phycisphaeraceae bacterium TaxID=2026777 RepID=A0A2D5Z4I2_9BACT -----ERKLDEMLAAFPGRAGVVIRDLADGRTC-AREADHRFPTASVFKVPIMVELFRQVE -AGMHRFDDRHRIHRGLCRHGTHVDDCAVGTTWSLLDLCERMIVHSHDVATDLILDVI-GL -ESINRTMDALGFADTRVCMPIGRWHYYTDREHNNVTSARDMADMLERMRAGKLLNPAASK -QMLDMLHRCAH-RGMIPRHLDPKIPVAHKHGQSAR-IRADVGIVELPGR-PLIISVLTLA -VEGEARPGRELIAELSRQVV--- ->[subseq from] Beta-lactamase CARB-6 n=1 Tax=bacterium HR15 TaxID=2035410 RepID=A0A2H5WTX3_9BACT ---RLKAKLDAICERFRGVMGYSLYHTRYQHRL-NRLGDEIFPTASTIKTAVMAKAFEEIE -AGRLNYNESIPITPDDIRDGAGLLQFFREKQVPVKMLLHLMITVSDNTATVILARRL-GT -VEVNRYLERLGLKHTRLLMLHPELKELRDRWGMGMCTPNEMVELLDAIRTGKAGTPAACD -RMLRILSHQFY-DNLIASSVPPWVVAATKSGAIER-SRSDTGIVFSPSGA-YILAVYTKE -AESPDNEGEIAIREVAREVWRFy ->[subseq from] Serine hydrolase n=2 Tax=unclassified Sphingobacterium TaxID=2609468 RepID=A0A358XSI3_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD -QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEALTRKLSKLLWDYy ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7LJ47_9BACT ---TLRARLEARIAQAPAQVGLYYRSLARPDSI-LIGATLRLHAASTMKVPVMIQIFRDAD -AGLLELNDSLTVHTASLVQGAAFTYAVVGQNRSVRDLLELMITRSSNLATNILIERV-GA -SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAAGRAASRAACD -SMLVILGRQEF-NEGIPAGVPSGTRVAHKTGWIGEVVYHDAGVVYPPHGGSYVLVVLTGG -IKED-SVAHNLVADVSRMVWE-- ->[subseq from] class A beta-lactamase n=1 Tax=Alistipes sp. Z76 TaxID=2304565 RepID=UPI00136C76A4 --dALRDSISAIISDVTGEIGVAVI-IDSKDTV-TVNDIDKYALMSVFKMHQAVAICHSFD -LKGTPLDTIIEIDRTSLNPWSPMLKEHDNEHIPVSELLRYTLMQSDNNASNLMFDRLVSV -AETDSFIATIPRNSFRITERESDMQSDHSRSYNNHSSPLGVAMLVERLFTDSILSHEKQE -FICETVRSCSTGTDRIAAPLKDGITIAHKTGSGYINAHNDAAYITLPDGTSYTLVILVKD -FAGNEKQAAAIMARISDTVYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf265 TaxID=1736315 RepID=A0A0S9LRW1_9BURK ------------------------------------------------------------- ------------------------------------------------------------- --RAEAVRRALELPPDALRTDIDAAYAGYYAEGHNSATLVGYGAMLERLVRGELLSRTSTE -RLVQAMKFGTRGNYRLEAGLPKNLRLIHKTGTQHQ-RACHMGVVQPQDGDATVVAVCAAE -LD-EQRAAGRLFEAVGRAIA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas straminea TaxID=47882 RepID=A0A1I1REX8_PSEOC ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALDMKPEQLERDIDQAYRRYYESGLNSATLVAYGQLLGKLAKGELLSRPSTE -LLYDIMGLDSYEAYRLEAGLSEQLPFIQKTGTQR-GRACHMGIANPEGEDALVILACAEA -LDED-AEAGKLFERVGEAI---- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536CXJ6_9CHLR -------------SAIPGIAGAIALAE-DGTALyEHAADDEFPSASVIKVPLVMALYADAA -EGRIDLGERVAVGA--LVDGSGVLRYLADVRMTLRDLAMLAIIVSDNTATNRLIDRF-GL -ERVNDRLAAWGCSRTRLRRKMYDFDAA-AKGSENVTTPRETAALLLRLLRGGCRDRATSD -AVLAILERCQD-KTMLRRYLPPAAKVAHKTGTLDE-SRNDAAIVAVDRR--VVVSGFVRS -LR--------------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=Q2FC56_STAEP ----HSKELNNLEKKYNANIGVYALDTKSGKEV-KYNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIIKEIGGI -KTIKKRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] hypothetical protein n=1 Tax=Micromonospora inositola TaxID=47865 RepID=UPI0012FD723E -------QLARVAAGTNNRAGVTVRDLSGHQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQLSLDRGVLVTRADVVGGTGKLKFAIPQVVTIHRLTEYMIEYSDNTAANVLIDQLGGF -APVNALIDSMNQRETVLAHKFFD--DANDRGGENYTSPDDVISLLGAVWDAQILTESSRD -LMIDFMRKQTL-NTKIPAALPPRTPLAHKTGDLSD-VSHDVGYCLTPRA-EIAVAFLTAG -PFQS---GSETVRQLARTVHD-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7QNE2_9BACT -------------------------------YV-DLAADSSFHAASTMKVPVMIELFRRAN -TGSFGMNQGLLMVNQSLVDGSRYAYHRIGDRVSVDTLLRLMITRSSNFATNTLITLV-GA -EEVTRTMRALGAQRIQVLRGVEDGK-AFEKGLNNTTTARDLAIILRAIQEGKAASPPATR -EMLAILLAQEF-NEKIPAGLPPGTRVAHKTGEIT-AVSHDAAIVYPAGRKPYVLVVLTRG -IT-DGAKASKLIADLSSIIYQH- ->[subseq from] Serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf267 TaxID=1736316 RepID=A0A0Q4XMZ6_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -RRVDAVRRALQLQPADLQRDIAEAYARYYASGRNSVSLVAYGGLLERLVRGELLAPAGTA -RLFKALKFETRGDYRLEAGLPPQVRFIHKTGTQFE-RACHMGVIDPQDGQAIVLAVCAAG -LD-EHRVAGRLFEQVGTAI---- ->[subseq from] serine hydrolase n=1 Tax=Nocardia xishanensis TaxID=238964 RepID=UPI00082FCE3B ----AEDRIRAVFADAGCSGWLHARRCDGSATEiSVGGDERVVLASVYKLPLFVAFCRHVD -SGRIDPATRLTVTPSDCTPPTGIAAMRDPVTMSLRDLATSMMTVSDNAAADVLLGET-GL -GAVESLVDDLGLTNTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGTVLSAEQTE -FVRTVMRHQVW-PHRVAAGFPRSVSTAGKTGTIGV-IRNEVAVVEFPGEYPVAVAIFTRA -ARADLPVVDAAIAETARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacteriaceae bacterium CUG 91308 TaxID=2483804 RepID=UPI00131DC7E5 ---DLKNTILGNISEIKGNFAIAFHNLATSEQL-LINEKEVFHAASTMKTPVMIEIYKQAA -EGSFDLSDSIPIINEFKSIYDGSLYNQIGQKTTIYELMYQMITKSSNLATNILIEKV-DA -KKVTQTMRDLGAADIEVLRGVEDQK-AYDADMSNTVTAFDLMVILEAIASGKAVNQEASS -HMLVILSDQYF-NDLIPKYLPEGVKVAHKTGSIT-GVQHDSAIVELADGNRYVLVILSKN -LT-DVPKGKEAIAQISKLIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Muricauda zhangzhouensis TaxID=1073328 RepID=A0A1H2SEW6_9FLAO --eALETKIRTQIDSIEGDVAVALLNLAEPSDTlFINESEEFHAASTMKVPVMIELFKQQA -SGKINLNDSILLINESIVDSSPYSYSKINTNVALKDLMYSMITVSSNLATNVLIELV-DA -KKVTATMRDLGADKIEVLRGVEDQK-AYDLGLSNSTTAKDLLIIMQAIATNKAGTETDCE -AMINILKDQQF-NEIIPHELPDNVEVAHKTGSIT-GVHHDAGIVYLPDGRSYVLVLLSKN -LK-DFDKGTEQLAGISKTIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A2T4X2J5_9BACT ----LKTNIEQQIETIEGDIAVGFLDLSEGNSI-LINVDEEFHAASTMKVPVMMELFKQQN -EGLINLNDSIVLVNESIVDGSLYSYSKIGTKQTLYDLIIPMITVSSNLATNVLIEIV-DP -KKVTNTMRELGAEHIEVLRGVEDQK-AYDLGLSNTATATDLMIIMKAIANGNAGTEEDCE -AMISILKDQKW-NDMIPLYLPTDVKVAHKTGTIT-GVHHDAAIVYPPNGKSYILVLMSKN -LK-DFDQGTEQLAKISKTIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5J1S7_9BACT ---TLNEQLERLSAQSKAQIAVAVHDLESGLRF-SLEGDRWFHAASTIKVAVLLALFRAAD -EGRVRLDDSLHVRNRFISAASSFHYQAIGRTAKISALAEGMIAVSSNLATNLLLDLV-GV -EYARKVLRDAQVEGVELRRGVED-HAAHERRINNEATANGLLTLLSAL-RGDFLSSESKE -QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DL-EQNGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga japonensis TaxID=104662 RepID=A0A562T8A3_CHIJA ---RLAAKLRPLLARHHGIAGIYVHHLKTNRVV-AINADTLFPTASTIKVPIMIGIFDRIE -KGELQYRQPLVYRDSLLYEGEDILGSFKDGEIGLDKVMMLMLTMSDNTASLWLQSLAGGG -QQINAWLEAQGFTHTRVNSRTPGREENRRQYGWGQTTPREMARLLEMIYKGEVVSKAASE -RMYRNLTRNYW-DTEGLLQVPPGVRTASKNGAVN-ASRSEVVMVNAPHGD-YVYSIITKE -NQERDNEAWELLRRVAGLIWQHy ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriales bacterium TaxID=2049428 RepID=A0A419EZ96_9BACT ----------TEISTIKGDVAVAFLNLNTSDSL-LINENENFHAASTMKTPVMIEVYKQDA -SGKFKLSDSITVHNESIVDGSIFKYANIGKQLTIKELVYDMITVSGNLSTNILMEIV-KA -ENVTKSMRELGAQKINVLRGVEDIK-AYEKGLSNTTTAKDLMIIFENIANYKIVSEDVCR -QMIDILLAQKF-NNIIPANLPKDVVVAHKTGSID-GIQHDSGIVYLPGGKKYVLVLLSKN -LE-SNVKAIPVLANISKLFYDY- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI001328F413 ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7JV20_9BACT --qDLAARIAARIAQTNQGVGVYYRRLDRPDSL-LVDARHRFHAASTMKVPVMIEVFRDAD -AGTLRLSDSLTVVNESIVDGSPYQYLRVGQKASVRDLLELMITVSSNLATDILIERV-GP -ARANATAHALGADSILVLRGVEDGV-AYRAGRNNTTTARDLGVLLAAIAEHRAASRVACD -SMLAILGRQHF-TEGIPAGLPPGARVYHKTGWVGQVVYHDAAYIEMPDGRRYVLVVTTGG -IQLD-TAAYNLVADVSRIIA--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0013310F42 ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI000235B27A ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf265 TaxID=1736315 RepID=UPI0009EA7088 ---RLTNALERIDAMPGPRIGVYVRALASGESA-SFRAGQSWYLASAVKVPVAIAVLRGIA -RGDYQLDTPVTLRADDYVDGAGATNRHAVGALPIRFLLEQMVIHSDNTASDMLIGLV-GL -EQVNAVTAEVAPAGFGPITRLAEVRRAYYATGLNAGRLDAYGELLVQLADGRLLPPAHTR -YLLGLMERVVTGSQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAAGTRVVV-VACTR -GALSLARAERALREVGAALC--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DD94F2C -------------------AGVTVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQVFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLTQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWDGEILTPASRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] hypothetical protein n=1 Tax=Rubrobacter aplysinae TaxID=909625 RepID=UPI00128DAE30 -------EVRKIVEDYEGTVGVYVQDKSGDWGY-GIRPDERFYAASVIKLPVMAAVYRKIE -AEELSLDETVATEDRDYAGGAGGLQWQEESVHTVSDYLWMMVKQSDNVATNLLVRTVGGP -GYVNEVANDLGAENTEIHNKVTDQRAAAPG-LDNYTTPRDMAEILSGIASGEAANEAHTG -EMLGLMRQNGP-ESWVGGDLPPEAEPACKVGWIN-GVYNDICLVQTEGE-PYIISVFSKY -GPPRVAPGVSTLGGISEEVW--- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium pseudoshottsii JCM 15466 TaxID=1136880 RepID=A0A117DVY9_9MYCO ---DLESRFAELEQKYEARLGVYVPGTDATAAV-EHRGDERFAFCSTFKGLLGAAVLHRYS ---IAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSDGTAANLLLQDIGGI -AAFNEYLRSLGDSVSRLDQMEPELNRNPPGDVRDTTTP---------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=2 Tax=Paenibacillus elgii TaxID=189691 RepID=A0A163TDJ6_9BACL --nQLEATIHQAASSVEGKVGIAV-DTAEGQIR--IHADELFPSASLIKIPILLEAYRQAQ -EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM -GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSPRDMIIFLKEIVDGSTLKQEAKD -AALQLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTN -LV-DNLPAQQVISTIGKAVFDY- ->[subseq from] serine hydrolase n=1 Tax=Thermoactinomyces daqus TaxID=1329516 RepID=UPI00051A7CE6 --qKLTQKLDDWKTGVGGTWGIWIEDLHTEQRW-SWNEAKTFYSASIIKVPIMIAVYRQAD -RGALELSREVILRKEDQVGGSGVLQHLTPGTFTVKDLVTLMIIQSDNTATNLLIDLL-GK -NVIRETMNELGMTGSTFYNKLMILPANPEG--INQITAEDMARVYKALATGKAISWHASQ -EMVQILKKQQL-NDCFPYFLPSKYEMAHKTGMVTR-ILHDSGIFYIGSRA-LILVALSEG -LN--YHEAQKGLGELARLAFDVy ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. 40-24 TaxID=1895843 RepID=A0A1Q4G7D9_9SPHI --kKLKSQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD -QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEALTRKLSKLLWDYy ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus acidilactici TaxID=1254 RepID=UPI0006B48850 ----VEGTIRDAFGDISGDTAVYVSPVDSDTEV--DSNDQPQRAASDIKLFVMVAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QIN------------- ->[subseq from] Serine hydrolase n=2 Tax=Lactobacillus sp. CBA3605 TaxID=2099788 RepID=A0A2R3JMF6_9LACO ---SIKQAINTSLSGLKGTTSVAVAATDSSAKV--VQNDQSQRAASLIKLFILITAYHQVD -SDQLNLDESYTLTANDKVGGTGTLQGLPTGSLSYREILKRMMDESDNTAANIMIDKVGGI -STINAEIERLDLSETQLERKMMDTA-ALADGKDNYTSVTDVATVLTKMYSGKLISRTADQ -AMLTIMRQNAN-HAKLPHDLPSDAIVYNKTGEYDYGVQNDAAIIKNTQGA-FVVVVLSQD -GDETE--QVT------------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. TaxID=341027 RepID=A0A3B9NDB7_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD -QMYRFMGNMFY-DERGLSQIPSTIQTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEALTRKLSKLLWDYy ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6I8N6_9BACT ----LTEQVERLTAESKARTAVSLHDLESGLRF-SLRGDRWFHAASTIKVAVLLALFRAVD -EGRVRLDDSLHVRNRFFSAGSPFQYQAIGRTAKISALAAGMITASSNLATNLLLDFL-GV -AYARNVLRDAQVQGVELRRGVEDH-AAHEKGINNEATADGLVTLLSAL-RGDFLRSESKE -QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIIYLPEREPYIAVILTEF -DS-EKEGRRETVAAISEAIYH-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium RIFCSPHIGHO2_02_FULL_34_12 TaxID=1801607 RepID=A0A1F6RCW6_9BACT -------QIKQKIRQYSLVCGVYIKPSWTETSI-NINGEAQFPAASLIKIPVAVVLLRNID -KGLIKWDTVLTLKPKHYAQGAGYLRKRAGTKLELREVFKLMITISDNTATNMIIDLLGGI -NKVNQEILKLGLKNTRLVNYLGDFKGT------NKTSPHDLAELFEKSLEGELLSSNSRK -IFKNTLLKVKN-KSLIKKGLGKFTKFAHKTGTIGI-CVGDAGIVYLPLWKRVTISIIVRR -PFNS-LQGQRIIREITQIVRE-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0011B39D24 ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITVYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKTGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax radicis TaxID=758826 RepID=A0A561D1L5_9BURK ------------------------------------------------------------- --------------------------------------------------------PM-GP -QRVDALARTIEVDKADFRKTMDEAYQRYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ -RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA -EDDEHGEAGKAFEQIGRAVT--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=UPI0010385DAE ------------------------------------------------------------- -----------------------------------------------------------GP -LRVEAVANALELKTDQLDRDLDEAYRRYYDSGLNSATLIAYGQLLGKLVSGDLLSRESQE -RLYDIMGLDSYDAYRLEAGLAKDLPFIQKTGTQQH-RACHIGVANPQDENALVIVACAEG -LDEN-DEAGKLFEQVGEAI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas sp. AG1028 TaxID=2572911 RepID=A0A561DWS6_9PSED ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALDMKPEQLERDIDQAYRRYYESGLNSATLVAYGQLLGKLAKGELLSRPSTE -LLYDIMGLDSYEAYRLEAGLSEQLPFIQKTGTQR-GRACHMGIANPEGEDALVILACAEA -LDED-AEAGKLFERVGEAI---- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TDK3_9BACT ---TLAEELERLTAESKARAAVAVHDLESGLRF-SLRGDRWFHAASTIKVAVLFAVFRAAD -EGRLQLDDSLHVRNRFISAGSPFHYGLIGRTAKVSVLAKEMISASSNLATNLLLDFV-GV -EYARKVLQDAQVSGVELRRGVED-HAAHEREINNEVTASGLLTLLSAI-RGDFLSNKSKE -QVIRILLEQRF-KSMIPAGLPPHATVAHKTGEIST-ACHDMGIVYLPERAPYIAVILTEF -DS-EREGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w) TaxID=278197 RepID=Q03I06_PEDPA ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. G1-14 TaxID=2003121 RepID=UPI000B49380C --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -VAINKLMSDLQLAQTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD -QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NVGKTNEAEELTRKLSKLLWDYy ->[subseq from] Beta-lactamase n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=W7RTH9_LYSSH -----EKIIQDLLHETPYKVHLFVKNPKNEQFLfSHQIGEAFSSASIIKVPILLAALAYFE -KYSISLHSSLPISPADWVDFSVISEQRLTQ-STVYELLVWMIITSDNTATNVLIDVV-GM -EFLNDYFRQIGLQETLLQRKMMDVER-LAMGLDNFTSAWDMAHLFTRIYQQDLLAPPYNR -LVIDILNRQRA-HEGLKRYLVDDVKLAHKTGGLDT-VDHDVGIVYSNSID-YLIGVFITN -VTEN-ELARQLIGRFSKVVYDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. OV194 TaxID=1881065 RepID=A0A1I2BC82_9BACI ---ELNNRVNDIISGQNGAYA---YWIETKDGHiEFQADEVFPAASLIKIPILIEAFRQTE -AGQIDLASRISLKQEVRVGGAGVLQLFSDESVTVADILTLMITVSDNMAANIMIEKT-GM -ERINDLLAELGCSQTVLQRKLMDFEA-VKQGKNNYTSARDVILQLKEIDRGGRLKDKSSQ -TILHILQNQQF-RYKLPAYMDEKITIANKTGELD-GVEHDAGIFTFKRE-KLFAAVLTKN -LP-SEAEGRQALALIGKALND-- ->[subseq from] Class A beta-lactamase n=1 Tax=Azospirillum sp. TaxID=34012 RepID=A0A316T3U2_9PROT --------------GSGSRVGIAVLS---GDKV-LTVGKGAMPLMSVFKMFVALNVLEHQE ------KDKVLIVTEEMINRYSPMLKDYPVVPISVAELLKYMVSASDNNATDILLAFGGDI -RATQDYVRGLGFPGIVLKVNEQEMHENIRNQYLNRAVPADVVKLLRVVRESELLTNENKR -FFEALMTETVTGADKIKKYLPSNVVVGHKTGSSDNGADNDVGFVRLPDGREYYLGVMIAD -SPMSDRDNAELIARISKIVYRHf ->[subseq from] serine hydrolase n=1 Tax=Salegentibacter sediminis TaxID=1930251 RepID=UPI0009BCFF20 ----FQEKIDSIFTESQGDFALAFKELSGEKGSiFINEHENFHAASTMKTPVMIEVFKQAE -AGKFSLDDSLLIKNESIFDGSSFKYSQIGKKISIKDLVIDMISQSSNLATNILIELV-DA -KEVNASMRKIGARDINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEALANGQAVNPEADK -EMLEILRLQQH-TDLIPALLPKEVKIANKTGWIT-GVHHDSALVELPDGRKYVLVLLSKN -MK-EMEKGTQMLSGISKMIYD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC58_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVS ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Pediococcus acidilactici DSM 20284 TaxID=862514 RepID=E0NH64_PEDAC ----VEGTIRDAFGDISGDNAVYVSPVDSDTEV-DFN-DQPQRAASDIKLFVMIAAYQQVK -DGELSLSDDYTLTDSDKVDGTGKLREMADGTISIKDLIGYMMEDSDNTAANIMIRKLGGM -AAVNHQIDKMGATDTKLERMLMDTD-ALEDGKDNYTSAKDLGTALKKIYNHQMVSRKYDE -EMLTILKQNGN-HTKLPHDLPTEATVYNKTGEFDYGVENDAAIFGNQKGA-FVIVVMSQD -GQRDE--QINAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas daroniae TaxID=2487519 RepID=A0A4Q9QN87_9PSED ------------------------------------------------------------- ---------------------------------------------------------L-GP -LRVEAVANALELKTDQLDRDLDEAYRRYYDSGLNSATLIAYGQLLGKLVSGDLLSRESQE -RLYDIMGLDSYDAYRLEAGLAKDLPFIQKTGTQQH-RACHIGVANPQDENALVIVACAEG -LDEN-DEAGKLFEQVGEAI---- ->[subseq from] serine hydrolase n=1 Tax=Lutibacter sp. SM1352 TaxID=1548456 RepID=UPI000E513B88 --eNLETTILSQIDSIDGTVAVAFFNLSAPEGSlFINVDEKFHAASTMKVPVMIELFKQAA -EEKFNLNDSILLKNESIVDSSLYSYNKIGSKVVISDLMYNMITVSSNLATNVLIELV-DA -KKVTATMRDLGAEHIEVLRGVEDQK-AYDKGLSNSTTARDLMLIMKAIANDRAGSQKDCA -SMLTILKNQQF-NDMIPLYLPKEVKVAHKTGSIT-GVHHDAGIVYLPNGRTYVLVLLSKN -LK-DFDKGTDQLAKISKTIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7XUX1_9BACT ------------------SLGIAFYDAQATIQW-AYNGDQYFHAASTMKLAVLLAVFRQVD -RGELGLDAPVHVRNRSIVNQEPFMYGHLGRTLTIRELAYWMITKSSNLATNLLVDVV-GI -QTIQHALDELDIDGVRILRGVEDQ-AAFDAGLNNEVTANGLLKLLRLIAEERAYSKNASD -EMLNILLEQQY-RGGIPAGLPKAARVAHKTGNIST-VHHDAGIVFIEDRKPYVLVILTQF -RAE--TGRGTAVADVSRDIYN-- ->[subseq from] Beta-lactamase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174QP24_9CLOT -------NVTDQIKALPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE -EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRTASE -AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETALWLY--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6E920_9BACT ---TLREALEKLARESKARVAVALLDLESGFRF-SLAGDRWFHAASTIKLAVLLAIFRAAD -EGRLRLDDSLHVRNHFVSAGSPFRYQAIGRTAKISALTEGMIVASSNLATNLLLDCL-GV -EYARNVLRNAQVSGVELRRGVEDQ-AAHEKGIDNEATADGLLTLLSAL-RGDFLKKESKE -QAIHVLLAQRF-NSMIPAGLPAHATVAHKTGEIST-ACHDVGIVYLPEREPYIAVILTEF -DA-EQNGRRETVAAISEVIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A411SZN1_ALCFA --eRLQERLEPVLAQEAARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA -QGRLSLDTVYPLPEGDRTPGTGILSQLPGVTLSLRELALLMIILSDNVATNALIDLL-GM -ANINAWCAQAGLQQTQLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLGSPALPESLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Paenibacillus sp. N2SHLJ1 TaxID=2527873 RepID=A0A4Q9DPW2_9BACL --eQLAQNITNLVRQAGGVWGIAVEDLQSGERF-GLNEHGGFMAASLIKLPIMAAVYAAAY -EGRLRLDDQVSLRAGDKAGGSGILQHMAPGMMSIKDLITLMIIQSDNTATNMLIDLI-GP -EPIRRTMLDLGMQQSVFANKTGLFLTDPPG--QNITTAADVSLLLRKLASGSFISRHACA -DMIAVMKLQQL-GNGLAERLPPEWQWAGKTGSLT-GIAHEAGVLYVGHR-SIIVSVLSES -TAN-PGDVRKMISSIGEQV---- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. MUM 13 TaxID=1678001 RepID=A0A1S2R5C0_9BACI ---NLQKKIESHIAEFPGRISYKID---SADQFiQKDAAECFQAASLIKIPIIMEGFRQIE -EGKMYLNERAEISDSDLAGGSGVLHALSKSGFTIEDMLTLMIIVSDNTATNMLIRKM-GI -NSIHQTIASLNLKKTVLGRYMMDFD-AIGKGFDNYTCADDMVTCLRSIHQGSFLSGESRR -HIIRIMEKQQL-VSKLPAMMNNEVTVASKNGAIP-GAEHDSAIITRGDVT--VYAAVLTD -SLESEEDGRRIISQIGRYIYEE- ->[subseq from] serine hydrolase n=1 Tax=Echinicola pacifica TaxID=346377 RepID=UPI0003778B57 ---DLEAQITSHFAEVQGDFALAFELLDEDSIRlLINDKAIFHAASTMKTPVMIELFKQVE -SGNLSMDDSVKVINQSIVDGSPYKYHRIGKNSTYRELNYEMITRSSNLATNILIEKL-DA -KNISHTMRELGAMDIEVLRGVEDLKA-FDRGLSNTTNAYDLMLIMKAIATGKAVSKSASE -SMIKILEDQHF-RTLIPRLLPKEVIVAHKTGGIT-GVRHDSAIVTLPDGRQYVLVILSKN -LS-DEPAGEQLISEVSRMIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A3M2B5D7_9BACT ----LKAKLDAICEKFRGVMGYSLYHTQHNHHI-DNHGDTIFPTASTIKVAVMSKAMEEID -AGRLGYADKLPITPDDIREGSGLLQFFKENQVEVKMLLHLMITVSDNTATIMLARRL-GT -VEVNRHLERLGLRNTKLLALHPELKALREKWGMGMCTPNEMVQLLDAIRTGRAASPAACE -RMLRIMSHQYY-DDLIGSSVPPWVVACLKSGAVNR-SRSDVGIVYAPSGA-YILAVYTKE -NETPDNEGEVAIREVAREVWRFy ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000750463F --eRLQERLEPVLAQEAARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA -QGRLSLDTVYPLPEGDRTPGTGILSQLPGVTLSLRELALLMIILSDNVATNALIDLL-GM -ANINAWCAQAGLQQTQLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLGSPALPESLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. UMB0893 TaxID=2066053 RepID=A0A2N5FLB7_9BACI ------LKLQELIDRYQGRVGLSLEL--DGDLY-EWNSTQVFPSASLIKLPILLTAFRQKE -QGILDFDEIVTIAEMKMTSGAGVLQALSESALSIADMVTLMIIVSDNMATNLLINKI-GV -SKVRDFMDELNLSGTELNRQMMDFA-AIDKGLNNWTTPSDMLKCLKAIGQNGFLSDESRG -QIAAILQKQQFTDKLSFLMDTEKIVIGSKTGELH-GVEHDCAIIQFKERT-VYAAVLMDE -IV-DKRYGRSTINEIGRLIYEE- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D6PZC0_9BACT ---ALDESVEALCVQHGTDVCIAYANLDTGRVW-MRFGDLVLHAASTMKIAVMYEAFRQHD -AGRLDLDAPVEVRNESIVDGSPYAYEHVGARLPARELVRRMMVRSSNLATNLMVEIL-GP -KSIQATLTSLGLRDMKVLRGVEDGP-AFERGLNNVATARDLMTLLREVHAGRSVTGASRA -AMREILLGQEF-NDLIPKGVPPDTAVAHKTGSITR-IRHDAAIVSPVNGPAYVLVVLTRG -FD-DRDAAAPVITEVSRLVWMH- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium detergens TaxID=1145106 RepID=A0A420ADJ6_9SPHI --kKLEKQIKQLIQGFQGEVGIYVHDLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE -KGQLQLDQEYVYRESQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINKLMSDLQLQHTRVNSQTEGRKADWEKYGWGQTTAKEMADLLTLIRQGKVVSVKSSD -RMYRFLGNMFY-DERALSQIPATVKAASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NQGKTNAAEVLTRNLSKLLWDYy ->[subseq from] Class A beta-lactamase n=1 Tax=Muribaculaceae bacterium TaxID=2498093 RepID=A0A4S4GH27_9BACT ----LKEKLTQYIADKNARIGIAVL-VNGRYSV-SINGDYAFPMLSVYKFPIAMAVAEYCR -MRDIDFSDSCLVTAGDLHRYSPMLKKYADVDITFDELLAYALQQSDNNASDILLNCIGGA -ASANEYVSATGIEGVTIKWSEDDMHIDVSRCYENSATPVAMAKLMWTFDS--QYNDTLSK -RIKQLMESCETGQARLAKPLESNAVIGHKTGTGFINAVNDAGYVHLPDGTHYSIAVFIAD -SYYDMEHTEDIIADISEMTA--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI000853C6F6 ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea candida TaxID=359159 RepID=UPI0005BA7D51 -------AFESLFRAAGVTGWLYATDIDTGHEV-GRGADEPLPTASMYKVALLIALCRQAE -AGVLDLAARVTVTAADRVTGPTGLSAMLDDVISLRDLAYLMIAVSDNTSADKLLALV-GF -DAVNGMLAEFGLKDTRVVQGAGEMNAALDPARANCSTPREMARLFAMIWRDEAASPESCA -WMRTVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRCESGVVEYPDGARYAVSVFTRS -FSTAQPRADAVIGTAARMAVDH- ->[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A5R9BQD8_PEDPE ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -AKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-26652 TaxID=1684141 RepID=UPI0006A78D33 --nELNNRVNDIISGQNGDYAYWIE-TEDG-HI-EFQADEVFPAASLIKIPILIEAFRQTE -AGQIDLASRISLKQEVRVGGAGVLQLFSDESVTVADILTLMITVSDNMAANIIIEKT-GM -ERINDLLAELGCSQTVLQRKLMDFEA-VKQGKNNYTSARDVILQLKEIDRGGRLKDKSSQ -TILHILQNQQF-RYKLPAYMDEKITIANKTGELD-GVEHDAGIFTFKRE-KLFAAVLTKN -LP-SEAEGRQALALIGKALND-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium cochlearium TaxID=1494 RepID=UPI000BBCB50F ------------------------------------NEYMVFPSASTIKLLIMARIMKEVK -EKKRNLEDKIILKDVYKCGGDGILKELNDGHFTLKEVITLMIIVSDNTATNILIDMI-GM -DNINCMGKELGLTNTELRRKMMDSE-AVKMGRENVTTAKDLSCILEMIYNRQLVDCEYSD -IMLDILKKQQV-TGRLDLYLPEDILIAHKTGDLDN-LEHDVGIVYHPRGN-YLICVLTKN -VS-TNKYGREIIGEISQKVYN-- ->[subseq from] Uncharacterized protein n=2 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A160IMD3_9BACI --kQMERSLSDLLASGKGVYGCSLFDFNTKENF-TYHENESFYAASIIKVPIMAAVFAHAF -EGKYRLKDKVYIQDEDFVPGDGVLKHLSAGMWTIHDLLVLMIIESDNTATNVLIDLV-GK -ENVHAYMKEWGFKTSHLHHKLQISPDRIPG-EFNVITPHEINAFLILIATGRVVSIKACE -MMINILKQQKM-NDLLPRYLPASWEAAHKTGYVS-GVEHNVGLFYFPGHT-YAISVLSKN -VP-DRNEPRVIMGQIGHLLF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Laceyella sacchari TaxID=37482 RepID=A0A4R4AQM7_LACSH ---RLIQNLEHWKSNAVGNWGVWIEDLTSGTTW-VWNETKSFYAASIIKVPIMVAVYKQAF -LGRLALADEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT -ETIRETMDELGMRKSTFYNKLMIVPAAPAG--LNMITAADVAQCFRHIALGKAVSQYASR -QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTQ-TLHDAGILYTKSRA-MVMVALSEE -CE--YEQAQQQMKQLARLVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. M46 TaxID=2152717 RepID=A0A363NLE4_9SPHI --rKLEKQIKQLIQGFQGEVGIYVHNLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE -KGQLQLDQELIYRESQKYGGSGLMQFFKDSSVDLKTLVALMLSYSDNVTSIWNQKLAGGG -MAINTLMADLQLQHTRVNSQTEGRKTDWEKYGWGQTTPKEMADLLTLIRQGKVISEKSSD -RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVMLVNAPKGD-YVFSIFTKN -NGGKTNAAEILTRKLSKLLWDYy ->[subseq from] Putative Beta-lactamase n=1 Tax=mine drainage metagenome TaxID=410659 RepID=E6PD01_9ZZZZ ---ALRDSLHSLALSSDANVGIAVEDLATGAIT-GYNLNRSMPAASTIKIPVMVEVFRQMA -RGRFTLTHVMHLRVQDRDYGSGDLAYAPGAPVTVKRLLSEMIDVSDNTAANMLIRLV-GR -QRINAAMQAYGCHHTYLRTAIRTNVSSV--ETNLRTTPLDMLTLLVRMAHGKLVDTWSSH -AMLEILAHQEI-DTLLPEPLPDGTTIAHKTGSLHD-VMADVGIVYEPGA-PFAIAAMTSG -LPD-PQLGRDIVRQA-------- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UE11_9BACT --kKLEARVAETADRIDGVTGVAILDLTDGRIL-LHNADRVFPTASSIKIAILLELYRQDQ -KEKSQLDDNYTFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMVAVSDNAAANILIDRV-GK -DNVNAMLHGLGLSKTMLRRKMIDIAAARRG-DENVATPQEMARLLEAIYKGKALSKQATA -EFIKQLSTKKG--SYIPRYLPESVQVANKPGELE-AVRTDSGIVFCS------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7L2W3_9BACT -----RDRLEVRIARAAQAVGLYYRSLTRPDSV-LIGANLRLHAASTMKVPVMIQIFRDAD -AGLLRLDDSLTVHTASLVPGAAFTYAVVGRNRSVRELLELMITRSSNLATNILIERV-GA -SRAQASARSLGAWSIQVLRGVEDGA-AYRAGLSNTTTARDLGVLLAAIAAGRAASRAACD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAGVVYPPDGGSYVLVVLTGG -IKED-SVAHNLVADLSRLVYE-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI00066AE1D6 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMQEKLVRGELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] serine hydrolase n=1 Tax=Alicyclobacillus macrosporangiidus TaxID=392015 RepID=UPI00068D69E7 --tELSQRIHGLVSTLRGMCSVAIES-KEGNIY--VRADDRVPAASLIKIPILLEGLRQVH -AGRVSLEQPIRISDVEVVWGTGIIQLMSRNIWTFRDLLTLMIIVSDNTATNVIIDML-GM -ERVNALASDLGCSNTVLARKMMDFQAR-KEGLDNFTSAREVLVFLKEMVSGNTLPDSMKD -LARQIMAGQQL-NHKLPGDIPRDMEIAHKTGELR-GIEHDAGIITFGGN-RVYAAVLTWD -MEE-NAAGQRLIAAVGRAVFDY- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536IPT8_9CHLR -----------------GIAGAIALA-EDGTALyEHAADDEFPSASVIKVPLVMALYADAA -EGRIDLGERVAVGA--LVDGSGVLRYLADVRMTLRDLAMLAIIVSDNTATNRLIDRF-GL -ERVNDRLAAWGCSRTRLRRKMYDFDAA-AKGSENVTTPRETAALLLRLLRGGCRDRATSD -AVLAILERCQD-KTMLRRYLPPAAKVAHKTGTLDE-SRNDAAIVAVDRR--VVVSGFVRS -LR--------------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plajomi TaxID=1457217 RepID=UPI0010F6EA0A ---AVQKTVTTTMGGLSGKTAVAVMPLSGQPAV--IWHNQPQRAASVIKLYILATVYQRVA -AGKLDLDQHYVLKTSDQVGGSGTLQSLPAGTLTYRDVTQRMITVSDNAASNIMIHAVGGL -DAVNAEIKALGLRQTKLNRYLMDTA-ALKAGHDNVTSVSDVASLLRRLANHQLVSARASR -AMLAILKQTAN-HTKLPHALPAAATVYNKTGEFDYGVQNDAAIIQNQRGT-IIVVVLAEA -GQ--REAQINAMSDLGRALYEQ- ->[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009DB9FC2 ------------------------------------------------------------- ----------------------------------------------------------NGP -ARVEAIRRAADVKRTELATTMDEAYDRYYRRDLNTTTLIAYGAMLERLVRGQVLPDAPRA -LLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAIR--- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Sphingobacterium TaxID=28453 RepID=A0A653Z801_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRASQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -VAINKLMSDLQLAHTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD -QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEVLTRKLSKLLWDYy ->[subseq from] Uncharacterized protein n=1 Tax=Atopobium vaginae PB189-T1-4 TaxID=866774 RepID=E1L327_9ACTN ---ALKSELEQVVAPYGNAVSVSVVAIRTGATC-DINANKQVISASMIKLAVMAAYLQAVD -AGTINPQQALPLARIKIVGGTGKIQSERARTYTYDALCRYMIMYSDNTATNALIDDL-GV -DAVNSRARELGCTHTTLNRKLMQLNTG----VENYTSAADVSRLLCAFYTQTAASAGQCT -KAMDFLLQQTD-GDGIPQGLS-GVQFAHKTGTLS-GIRHDGGIVM--ERSPYTIVVMCEL -PEG---KANALMAQVARKTQQYf ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax sp. CF316 TaxID=1144317 RepID=J1E9U4_9BURK ------------------------------------------------------------- --------------------------------------------------------PM-GP -QRVDALARTIEVDKADFRKTMDEAYRRYYARGLNSAPLTSYGGMLEKLVTGKLLSPAHQQ -RLFTDLKYATYDAYRLEAGLPRSERFIHKTGTQLH-RACHMGVVNPQDGGRAAIVVATCA -EDDEHGEAGKAFEQIGRAIT--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A5P0DKN6_ECOLX ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQ----------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LP02_9BACT ------EELERLTAESKARAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAQGMISASSNLATNLLLDFV-GV -EYARKVLQDAQVSGVELRRGVEDH-AAHERGINNEVTANGLLMLLSA-VRGDFLSNQSKE -QAIRILLEQRS-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EQEGRRETVAAISEVIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6M6V4_9BACT ---TLREALEKLARESKARVAVALLDLESGFRF-SLAGDRWFHAASTIKLAVLLAIFRAAD -EGRLRLDDSLHVRNHFVSAGSPFRYQAIGRTAKISALTEGMIVASSNLATNLLLDCL-GV -EYARNVLRDAQVSGVELRRGVEDQ-AAHEKGIDNEATADGLLTLLSAL-RGDFLKKESKE -QAIHVLLAQRF-NSMIPAGLPAHATVAHKTGEIST-ACHDVGIVYLPEREPYIAVILTEF -DA-EQNGRRETVAAISEVIYR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=Q2FC40_STAHA ----HXKELNXLEKKYNAXIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=UPI0009FB6570 ------------------------------------------------------------- ----------------------------------------------------------NGP -ARVEAIRRAVDAKRTDLATTMDEAYDRYYRRDLNTTTLIAYGGMLERLVRGQVLPDPPRA -VLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAIR--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5M2D0_9BACT ----LNEELETLSSESKARIAVALHDLESGLQF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV -EYARNVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVRLLSAL-RGGFLSPQSKE -QAIGILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDIGIVYLPEREPYVAVILTEF -DSE-GDGRREIVAAISEAIYR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5QBF7_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-LYRADERIAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGP -ASVTAFARQLGDETFRLDR----------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter salegens TaxID=143223 RepID=A0A1M7IZI2_9FLAO --eKLQEKIDSIFKSIQGDFAIAFKDFSEEKDSiLINHHEDFHAASTMKTPVMIEVFKQSS -AGKFSLQDSLVVKNQSILDESYYSYEQIDQKRSIEDLVIDMIIYSSNLATNIIIELV-DA -ENVNKTMREIGAMNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFDALANGDAVNPEADE -EMLNILRQQKH-TDLIPHLLPKDLKIANKTGWIT-GVHHDSALVELPDGRKYVLVLLSKN -IE-DMDAGTKMLTEVSKMIYDH- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GYL6_9BACT ---ALIEELERLTAESKTRAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAEGMISASSNLATNLLLDFV-GV -EYARKVLQDAQVSGVELRRGVEDH-AAHERGINNEVTANGLLMLLSA-VRGDFLSNQSKE -QAIRILLEQRF-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EQEGRRETVAAISEVIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inositola TaxID=47865 RepID=A0A1C5K381_9ACTN -------QLARVAAGTNNRAGVTVRDLSGHQQI-AVNGTFRPKAASVIKLWILVELLRRVD -CGQLSLDRGVLVTRADVVGGTGKLKFAIPQVVTIHRLTEYMIEYSDNTAANVLIDQLGGF -APVNALIDSMNQRETVLAHKFFD--DANDRGGENYTSPDDVISLLGAVWDAQILTESSRD -LMIDFMRKQTL-NTKIPAALPPRTPLAHKTGDLSD-VSHDVGYCLTPRA-EIAVAFLTAG -PFQS---GSETVRQLARTVHD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Brugia malayi TaxID=6279 RepID=A0A4E9G452_BRUMA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGQAGTK-------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Brugia malayi TaxID=6279 RepID=A0A5S6PD49_BRUMA ---ETLVKVKDAEDQLGARVGYIELDLNSGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -AGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP -KELTAFLHNMGQAGTK-------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=8 Tax=Bacteroides TaxID=816 RepID=A0A6A2GHF0_BACUN ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGDNGAHNDVAYICLPNNVCYTLAIFVKD -FKGNESQASQYVAHISEVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7RH68_9BACT --qDLAARIAARIAQTNQGVGVYYRRLDRPDSL-LVDARHRFHAASTMKVPVMIEVFRDAD -AGTLRLSDSLTVVNESIVDGSPYQYLRVGQKASVRDLLELMITVSSNLATDILIERV-GP -ARANATAHALGADSILVLRGVEDGV-AYRAGRNNTTTARDLGVLLAAIAEHRAASRVACD -SMLAILGRQHF-TEGIPAGLPPGARVYHKTGWVGQVVYHDAAYIEMPDGRRYVLVVTTGG -IQLD-TAAYHLVADVSRMIA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Arcticibacter pallidicorallinus TaxID=1259464 RepID=A0A2T0U601_9SPHI ----------------EAAFAVSYRDIDTGDKF-NINERESFHAASTMKTAVLAEVYKQAH -DGKFSLDDSILVQNSSIVDGSSFAYNLIGSHVSIRDILIRMVTRSSNLATNIIIEKI-GA -ENVNHTMRSLGAKDLRVLRGVEDIKA-FEQGLNNTTTANDLAVILEKIARNELINAQASE -EMIDILMNQYD-KNIIGGKLPLDVKVASKSGAITS-ICHDSGIVFLPDGRRYVVVLLSRG -ID-NHKAASQLLSNVSKHIYEY- ->[subseq from] Serine hydrolase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=A0A5P0YF09_9BACI --kQMERSLSDLLASGKGIYGCSLFDFKTKENF-TYHENESFYAASIIKVPIMAAVFAHAF -EGNYRLKDKVYIQDEDFVPGDGVLKHLSAGMWTIHDLLVLMIIESDNTATNVLIDLV-GK -ENVHAYMKEWGFKTSHLHHKLQISPDRIPG-EFNVITPHEINAFLILIATGRVVSIKACE -MMINILKQQKM-NDLLPRYLPASWEAAHKTGYVS-GVEHNVGLFYFPGHT-YAISVLSKN -VP-DRNEPREIMGQIGHLLF--- ->[subseq from] Beta-lactamase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A379BQU3_PEDPE ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=UPI000E369269 ------------------------------------------------------------- ------------------------------------------------------------- -------ARVLNLQQDELKASMEQAYERYYARQLNSSSLVAYGTMLEKLVRVELLSAESRD -LLYGFMKLDSYDNYRLEAGLPEDVPFIQKTGTQLE-RACHVGVIEPQDERRAIVVVACAE -GLDEGKEAGSLFEQVGQAIS--- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=A0A368XHV2_9BURK --eRLTAALAHIDAAPDGRIGVYVRALGSGESA-SFQAEQSWYLASAVKVPVAVAVLRGIA -RGVYQLDTPVTLRADDYVDGAGSTNRAVGAALPIRYLLEQMVIHSDNTASDMLIGLV-GL -AQVNAVTAEVAPGGFGPITRLAEVRRAYYATGLNAGRLDAYGELLAQLADGQLLPPTQTR -YLLGLMERVVTGPQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAGGT-RVVVVACTR -GELSLVRAERALREVGTALC--- ->[subseq from] Serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A512K880_PEDPE ---TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEEMMEDSDNTAANIVIRQLGGM -NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI00049384CF ---TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEEMMEDSDNTAANIVIRQLGGM -NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. CRM56-3 TaxID=2678357 RepID=UPI0012D3CE69 ----AQRQIRTIEQRTSGRTSVYVRNLQTKRPVvMH--NRQQRSASVIKLFIMIAVFRQIK -LGRLSASQMVTIPKQDRVGGTGVLASQSTKQLSVNQLLTLMIRNSDNTATNVLIDQLGGL -RPVNTEIQRLGCTQTVLQRKMLDYQ-ALKNGKDNLTSVADVGHVLGKLYQHQILGNPYDA -QMLQLLRHNAN-QSKIPTLINQKAIIYNKTGEFDYGVQNDAAIVKKGHQA-FVAVVLSEN -GAQ--NRQIKAMQQLGR------ ->[subseq from] CfxA family class A extended-spectrum beta-lactamase n=1 Tax=Porphyromonadaceae bacterium TaxID=2049046 RepID=A0A3B8QYE7_9PORP ---SLRDELYALVDTVPGTVGIAFIC--DNDTA-TVNNGVKYPMMSVFKFHQALGVAETVE -KRWNTLDSMLLVHSNELDRWSPMLKKYPEGDISISELLSYAITKSDNNASNLMFKHILSP -GETNDFVKSIRDTTFQIRYSESEMKAKHPLSYLNCTSPLAAASLMRQVFEEQLVDAAAQD -SIRHYLSIVTTGHDRLGAAVEDIMIFAHKTGSGYRNAHNDVGYFRLKDGRSYSLAVFIRD -FRGSEEEASAVIANISKCVYNRf ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Entotheonella TaxID=93171 RepID=W4LS93_9BACT -------------NEAHGSIGVSAIS-PCGERW-EVQGKTRFPAASTVKIPIMIEIYRGID -RGELAIDDTYIVRSADKAPGSGVLQHHAGLQLSLGDLLYLMMSISDNTATNILIDMA-GM -DRINATMQDLGMAASTLGRPMRGRL-AIEGEEENWATPNDYTAVVKALIDEQAASPAACQ -AMLTTLTLQQN-HRRIGRYVPKSYRWGSKTGSNT-GITNDVGFVQSPAGT-MIIALYSQG -IG-DAVTSEIALSDIAEAAMQ-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia asiatica TaxID=209252 RepID=UPI0002F09BA8 --------IRAVFADAGCSGWLHARRCDSATEI-SVGGAERVVLASVYKLPLFVAFCRLVD -AGRLDPATRLTVTPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL -GAVEDLLNDLGLTHTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGAVLSDEQTE -FVRTVMRHQVW-PHRVTAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAIFTRA -ARADLPVVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase TEM-12 n=2 Tax=Bacteria TaxID=2 RepID=A0A2H5WMU3_9BACT ---KLKARLDAICEKFRGVMGYSLFHKRYQHRI-HRLGDEIFPTASTIKVAVMSKAFEEID -AGRLSYNEKLPITPDDIRDGSGLLQFFKENQVEVRMLIHLMITVSDNTATIMLARRL-GT -VEVNKHLQRLGLKDTRLLALHPELKAYREKWGMGMCTPNEMVALLDAILTNRAGTPAACE -RMIRIMAHQYY-DDLIGSSVPPWVVCATKSGAISR-SRSDVGIVFAPSGT-YILAVYTKE -AETPDNEGEVAIRAVAHEVWKFy ->[subseq from] serine hydrolase n=1 Tax=Clostridium bornimense TaxID=1216932 RepID=UPI0006888D76 ----------------TSNYSLAFKDLSQKSTL-SINSEKT-ISASTIKIYIMIETFNQIK -SGNINLDDTVILEESMKTDGSGMLSSKATGEFTINELITLMMIKSDNTAANILIDKI-GM -ESINNCIKNLGCKDTELNRKMMDAT-AIEKGVENYTSVDDLCLTLEKLYNKQCIDEYYDN -LMLDIMKKNEN-HTKIPKLLPDTLSIANKSGEYT-GVENDAAIITTDKGA-YVLCITTSN -GGS--GSQIKTINNISKDIYNKf ->[subseq from] Beta-lactamase n=1 Tax=Clostridium hathewayi CAG:224 TaxID=1263067 RepID=R5TCG1_9CLOT -------NVTDQIKGLPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE -EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRTASE -AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETALWLY--- ->[subseq from] serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0003C3376C ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -NKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI001008EB5D ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -NKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoflavimicrobium dichotomicum TaxID=46223 RepID=A0A1I3UDI7_9BACL --qKLEEKIGQLLEAFSGKAGVAVE-TEEGW-I-GFHENEPFLAASLIKVPIMIETYRQVQ -EGRLSLSQLYQIPEKKRVGGSGVLSSLREQVVSLQDLISLMIMVSDNTATNLLIEQV-GF -DAVNQLASKLKCDQTLLGRKLMDYAAK-RRGLENFTSAGDMVRFFKEIMEGSLLNETYKN -CALDVLKKQQF-QAKLPGHLEGHDFIAHKTGEMRD-YEHDAGILSVNGK-IAYVAVLTSH -GT-DAFSRRNLIADVGKALFDY- ->[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A150WBR7_BDEBC --kNFEESLKELESKQPIQLGVFVKNLSTGEVL-SYRGEDLWYVASGVKLPIVLENLRQVD -QKKYTLNSQIELRKEDFVDGAGYTNYKKAGSLSVKFLVEQALIYSDNTASDLLIRQA-GL -DSVNSCIQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK -FLIETMTKVQTGPHRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGVVIAACVKD -FK-SLDVAESALKSVGVA----- ->[subseq from] Beta-lactamase n=2 Tax=Micromonospora lupini TaxID=285679 RepID=I0KXC6_9ACTN ----------------------------GDQQI-SVNGALRPKAASVIKLWILVELLRRVD -CGQVSLDDGVLVTPADVVGGTGQLQFETPQVVTLYRLARYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGTVWDGEILTPDSRD -LMIGFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E0F9M0_9BACT ----LENKISNLIKSHKGTFAVALKSLDDGNTI-LINENEIFHAASTMKTPVMIELFKKKH -NGEVSFEDSLQIKNESIVDGSKFEYKKLGKYISIRELVSAMITKSSNLSTNLLIDYI-NV -KNVNKTMRDMGAENINVLRGVGDLKA-FDKGLNNTTSAKDLLVIYEKLAMGLFINPSISN -EMVEILKNQVY-KDIIPKYLPDNIEVAHKTGWIS-GVRHDSGIVFLENGKKYVLILLSKN -LDD-DIEGAEFLAKISLEIFN-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. CZ-UAM TaxID=1933868 RepID=A0A1V3MWC2_9SPHI --kKLEKQIKQLIQGFQGEVGIYVHDLKKHKEV-NIGADSIFPTASVVKIPILVGVFDKIE -KGQLQLDQEYIYRESQKYGGSGLMQFFKDSSVDLKTLIALMLSYSDNVTSIWNQKLAGGG -IAINRLMADLQLTHTRVNSQTEGRKADWEKYGWGQTTPKEMADLLTLIRQGKVVSAKSAD -RMYRFLGNMFY-DERGLSQIPATVKSASKTGSLDD-VRNEVILVNASKGD-YVFSIFTKN -NQGKTNAAEVLTRDLSKLLWDYf ->[subseq from] Putative membrane protein n=1 Tax=Clostridium bornimense TaxID=1216932 RepID=W6S7R4_9CLOT ----------------TSNYSLAFKDLSQKSTL-SINSEKT-ISASTIKIYIMIETFNQIK -SGNINLDDTVILEESMKTDGSGMLSSKATGEFTINELITLMMIKSDNTAANILIDKI-GM -ESINNCIKNLGCKDTELNRKMMDAT-AIEKGVENYTSVDDLCLTLEKLYNKQCIDEYYDN -LMLDIMKKNEN-HTKIPKLLPDTLSIANKSGEYT-GVENDAAIITTDKGA-YVLCITTSN -GGS--GSQIKTINNISKDIYNKf ->[subseq from] serine hydrolase n=1 Tax=Clostridium lundense TaxID=319475 RepID=UPI0005560C11 ------DKVKEEIDGFKGTCGVIIKNENTGDCL-QYNEDVVFPAASIIKLSILLELFKKVD -NGDINLQERVVLKESEKVDGFGVLKELDCDVLTIKDLATLMIILSDNVATNKLIHIL-DM -ESINNTIKELGMKDTVLGRKMMDGEA-KKKGLDNYTSAKDTLIMLEAYLNYSKLSAKNRE -TILDILKKQQC-NNKLPLLMPKDISFGHKTGDLP-GVEHDAGIIFSKIGQ-IIIIVLTKD -LEK-NTYGVQLNNNIGKIVAEY- ->[subseq from] serine hydrolase n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=UPI0012DA7FD6 --kNFEESLKELESKQPIQLGVFVKNLSTGEVL-SYRGEDLWYVASGVKLPIVLENLRQVD -QKKYTLNSQIELRKEDFVDGAGYTNYKKAGSLSVKFLVEQALIYSDNTASDLLIRQA-GL -DSVNSCIQDLVPGGFTAITTLADVRRNYYSKKLNSATLKAYAELLEKVAEGKILGDSTQK -FLIETMTKVQTGPHRIKAGLPKKYSFAHKTGTQHS-RICDFGIAWDKKSTGVVIAACVKD -FK-SLDVAESALKSVGVA----- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522RA87_9BACT -------ILAEFAKQPTGTFAVAFKDISTGEIF-LMNAHESFHAASTMKTAILIETFKQAT -GHKFSLTDSILIKNSSIVDGSPFSYTRIGTKLPVNDLLYRMITESSNLATDLIVDLV-GA -ENANKTMHELGAKDIKVLRGVED-NKAYDLGLNNTVTAYDLMVIFDHIADGTVVNKKACD -AMIKILMHQHF-REKIPALLPADVRTATKSGSIDK-ISHDSGIVFLPDGRKYVVVLLSRG -IE-DEKSADETLARISRIIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7P8Z1_9BACT ---ALAQRLAERIARAPARVGLYYRSLAGSDSL-LIGANLRFHAASTMKVPVMIQIFRDAD -AGLLRLDDSLTVHTASLVPAEAFIYESVGRNRSVRELLELMITRSSNLATNILIERV-GA -VRAQASARALGAWSIQVLRGVEDGQ-AYRAGLNNTTTARDLGVLLIAIVQGRAASRPSCD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAAVVYPARGGPYVLTVLTGG -IKED-SVAHNLVADLSRLVY--- ->[subseq from] Beta-lactamase n=1 Tax=Sporomusa acidovorans DSM 3132 TaxID=1123286 RepID=A0A259V193_9FIRM ----LSEQVKNFSTQKEAKYAIYVRPLGEKGHD-VVLNSHKMASASLIKIPIMIEAFNQKN -QGKLDFNEQVTIRRAETVEGGSVYNLADGTVLTIAQLVELMIVQSDNSACNILIDKL-KM -DNVNAMIKKLGCSDTSLQRKMMDFAA-VKQGRQNYTNVTDMANILEKLYYGKCLDPKSDK -AMLEIMARQED-NTIIPAQLPHHIKIAHKTGELD-GMNYDCGIVYGQSRT-YILCMMAEN -VK-DE------------------ ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P299 TaxID=1805477 RepID=UPI00082CDF49 ---------------VEGKVGFYYKNLITGEII-TYQHEEAFEAASVIKIPILIEVYRKIM -DGSLHENQIFQVKEDDKLPCGALTYMHTGLEVTLKDLCTLMIILSDNTATNMLIKLV-GM -DQINETMRGLGLKKTKVNRLLFDSKQS-ALGIQNYITSGEIGILLEKMYDGSLISKEASK -EMISILMNQRL-NGKIPFYITDGTKVAHKTGEDS-GITHDVGIVFTK--EPFIVCFCSNN -VE--VPYFERVIQEISRD----- ->[subseq from] serine hydrolase n=1 Tax=Fictibacillus phosphorivorans TaxID=1221500 RepID=UPI0011A9CDEB --kQIEHSLSELFSSGKAMYGCSLYDFRTKESF-THYENETFYAASIIKVPIMAAVFAHAF -EGKCRLQDKVQIQEEDFVPGDGILKYLSAGMWTIYDLLVLMIIESDNTATNILIDLI-GL -ENISAHMSGWGLKKSQLKHKLQISPDR-KPSELNVITPNEINQFLTQLALGRVVSIKACD -MMIKILKQQKM-NDLLPSLLPPNWEAAHKTGDVS-GVEHNVGLFYFPGHT-YAISVLSKN -VPH-RTEPRRIMGEIGQLLF--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5L796_9BACT ---TLNEQLERLTGQSKAQIAVAVHDLESGLRF-SLEGDRWFHAASTIKVAVLLALFRAAD -EGRVRLDDSLHVRNRFISAASSFHYQAIGRTAKISALAEGMIAVSSNLATNLLLDLV-GV -EYARKVLRDAQVEGVELRRGVED-HAAHERRINNEATANGLLTLLSAL-RGDFLSSESKE -QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DL-EQNGRRETVAAISEAIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Ferruginibacter sp. BO-59 TaxID=2294116 RepID=A0A3M9N2V2_9BACT ------EILAEFAKQPAGTFAVAFEDLATGEQF-LMNAHENFHAASTIKTAFLIETFKQAD -EGKFSLNDSILIHNDSIVDESLYHYRRIGQKETIYNLLYRMITQSSNFATNLIVDLI-DA -KNANSTMRSIGAKNIQALRGVEDSK-AYELGLNNTVTAYDLMIIFDHLDKGTVVNKPACD -SMIQILMHQQL-REKIPAKLPANVKVANKTGSITK-ISHDSGIVFLPDGRKYVLVLLSKG -VE-DENAANETLARVSRIIYDY- ->[subseq from] CDP-alcohol phosphatidyltransferase n=1 Tax=Prevotella sp. khp7 TaxID=1761885 RepID=A0A1I0QQN8_9BACT ---------------------------RDGSVS-GVNQNERFAMHSVMKFPQALYVADYLG -RKGLALDDTIVVDKADLMQWSPMLKRFEGKGISYAELLELSLGQSDNNACELLFKYCGKP -KIVEKYMRKLGCRDIHVRMTEEQMHKNPAKAIENSSTPAEMVRLFEWFYHHKD-NNQYLT -FIWKAMADCSTGLKRIPAAIPAGARIVHKTGTGFVQDMNDAGIILMPDGSYAIIAVFTTH -SP-----SEAVIENIAKQLL--- ->[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI000E0C3701 ------------------------------------------------------------- ---------------------------------------------------------RNGP -ARVEAIRRAADVKRTDLATTMDEAYDRYYRRDLNTTTLIAYGAMLERLVRGQVLPDAPRA -LLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAI---- ->[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BCA4EC ---GVADRIRAVFADAGCTGWLHARRCGTTAEI-AVDGRDRVVTASVYKLVLFVAFCRRID -DGLIDPGARITVHPADCTPPTGIAALHDPVTMSHRDLATSMMTVSDNAAADILLGEI-GL -GAVEELLAELGLTETRIVGGTADVHRAYDPSYASATTPEDMTRLLQLVWGGGVLSPEQTG -FVRAVMRKQVW-PHRIASAFPRGVFVAGKTGTIGV-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus haemolyticus TaxID=1283 RepID=Q2FC70_STAHA ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SC08_9BACT ----LHEELEALALKNKARIGVALHDLETGFRF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLDDSLHVRNRFFSAADGSLYAAIGRTTKISALAHAMICGSSNLAANLLLDFV-GV -EYARTVLREAQVDGVELRRGVEDH-GAHERAINNEATADGLLSLLSAI-RGDFLTPESKR -EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIVYLPEREPYIAAILTEF -DS-EREGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptosporangium subroseum TaxID=106412 RepID=A0A239NPD8_9ACTN -------AIEGLFRTAGVTGSLHVMDIDTGAEV-AYDADGSVVVASVFKVALLVELFRQAD -RGVLDPAERVTVMADRHTAGSTGVSVMADDVMSLRDLAYLMIAVSDNTAADAVIDRV-GL -PAVNTMLAAFGLDRTWIEHDCRELFSALDPARTNRSTPRDMTRLLSMIWRDEAASPESCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides eggerthii TaxID=28111 RepID=UPI000E4C0C05 -----TDTISKIVAYYPGEIGVAVI-INNTDTI-TVNNKSIYPMMSVFKVHQALAICDDFG -HKGFSLDSLMTIHRDELDPWSPIMKEHLEPVLRVKDLLCYTLILSDNNASNFMFKKLVNI -TQTDSFIATIPRLSFQIAYTEEEMSADHDKAYANYTSPLGAAILMNRLFTDSLIDYDKQQ -FIIKTLEQCSTGKDRIAAPLKDGITIAHKTGSGYTNAHNDVAYIRLPNGICYTLAVFVKD -FKGNETQAAKAIAHISAIVYS-- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FED40 -------------------------------------------------------VLKQSE -TQKQLLNQPVEIKPADLVNYNPSAEKHVNGTRTLAELSAAALQYSDNTAMNKMMAQLGGP -GGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTPRAMAQTLRQLTLGHALGETQRA -QLVTWLKGNT-------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sporosarcina koreensis TaxID=334735 RepID=UPI00075E296F --kTLQEKIESRLKDAKGIWSVSVEDLNEGTSF-SLNGNELFYAASIIKVPIMAAVFAVAE -EGNIRLGDRLLLRRDDIVGGSGVLQFMSPGILPIYDLLTLMIIQSDNTATNMLMDLI-GM -EKIQAVMNGLGMERSEIHHKLMIAQTN--RVNSNEITATDVNALLTRIVRGECVSLHASE -QMIRIMKQQQLSNGLIDS-LPPDWEFAGKGGSVE-GILHECAILYARGR-CIAVTVLSKG -CSED--EARKTIAQIGSEVY--- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingomonadales bacterium 28-55-16 TaxID=1970589 RepID=A0A258RWT6_9SPHN ---KLKSEIDGYWKKFPGRAGIAIYTPFSDEII-GKRQTERFPQQSVSKMWVALTILEQEA -AGKLSLDKRIRITPDDVVVFSQPLKRYLDGKMPVRELLAHAINASDNLANSVLLRVAGGP -EAINQMLDRRKVQSIRFGPGEVLLQSAYLKAPLDGAAPGTIVLALKRFSERG--PNDPGA -KLLKIMAGTYTGRSRLRSGLAPHWSLAHKTGTGQSTALNDVGVMKAPDGCLYPVAVMIAE -TRSGKEVSNGLMQNVARAVIRH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC80_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides eggerthii TaxID=28111 RepID=A0A415RUU1_9BACE -----TDTISKIVAYYPGEIGVAVI-INNTDTI-TVNNKSIYPMMSVFKVHQALAICDDFG -HKGFSLDSLMTIHRDELDPWSPIMKEHLEPVLRVKDLLCYTLILSDNNASNFMFKKLVNI -TQTDSFIATIPRLSFQIAYTEEEMSADHDKAYANYTSPLGAAILMNRLFTDSLIDYDKQQ -FIIKTLEQCSTGKDRIAAPLKDGITIAHKTGSGYTNAHNDVAYIRLPNGICYTLAVFVKD -FKGNETQAAKAIAHISAIVYS-- ->[subseq from] Extended-spectrum beta-lactamaseR-1 n=1 Tax=Symbiodinium microadriaticum TaxID=2951 RepID=A0A1Q9CUT2_SYMMI --------------------------------------ERRFPMASTFKIPLALSVLQMVD -AGRFSLEQKFVLDAFDVRPGTGVLRDEIRTECSLYELLEKALNDSDNTATDVLLDRVGGP -SVVFEHLKKLGLDEIRVARSCLEHLREFDADLRDTTTPEAMAGLLEKIWNREAISDGSTQ -VLLEIMGHCRTGAKRILGRLPRYPRVQHKTGSLG-GRANDVGIVYLPNGHAFAICCYTKG -LAQSYEERERLIADVARACYD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=UPI000DF1273A --eRLTAALAHIDAAPDGRIGVYVRALGSGESA-SFQAEQSWYLASAVKVPVAVAVLRGIA -RGVYQLDTPVTLRADDYVDGAGSTNRAVGAALPIRYLLEQMVIHSDNTASDMLIGLV-GL -AQVNAVTAEVAPGGFGPITRLAEVRRAYYATGLNAGRLDAYGELLAQLADGQLLPPTQTR -YLLGLMERVVTGPQRIRAGLPAGARFAHKTGTQR-GRFCDAGIVQPAGGT-RVVVVACTR -GELSLVRAERALREVGTALC--- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5NEJ6_9BACT ---ALIEELERLTAESKARAAVALHDLESGLRF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLDDSLHVRNRFISAGSPFRYQAIGRTAKISDLAQGMISASSNLATNLLLDFV-GV -EYARKVLQDAQASGVELRRGVEDH-AAHERGINNDVTANGLLMLLSA-VRGDFLSNQSKE -QAIRILLEQRS-KSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EQEGRRETVAAISEVIYR-- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides fragilis TaxID=817 RepID=A0A5E8KG21_BACFG ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGNNGAHNDVAYICLPNNVCYTLAIFVKD -FKGNESQASQYVAHISEVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Limnochorda pilosa TaxID=1555112 RepID=A0A0K2SP07_9FIRM ----IYDELTELDAGFSGTLAVAARGLSRRPAL-SFRAAETFPAASVIKLPILVEAFRQAE -EGRLDLARRVPLRTEDQVGGSGVLKELEPGLPTLRDLLTLMIVVSDNTATNMVMERV-GI -EAVNASAQAWGLRQTYLAGPLLAPPEAQREGRRSTVSPADMVELLTALHRHQILSEAGCE -QVLEILGRQHF--SVLGRELGSDLRIQSKSGSIA-GVRNDVGIISTSHGA-YAVAVMTKD -SRAYQNEGETVVARASRLVFDHw ->[subseq from] serine hydrolase n=1 Tax=Nocardia jinanensis TaxID=382504 RepID=UPI0007386253 -----ADRIRAVFADAGCTGRLHARRCDGGDGQvSIGGTERVVTASVYKLPLLLAYCRAVD -SGRLDPLSRLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEV-GV -GTVHELLESLGLDHTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGQVVSQEQTD -FACSIMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Halomonas titanicae TaxID=664683 RepID=A0A558JFU3_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVTDTFTQPDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ -TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG -PLA-VSAHERALASVGEA----- ->[subseq from] Beta-lactamase n=2 Tax=Clostridium TaxID=1485 RepID=Q97MK6_CLOAB ----LKKTIENLITSNKEDISLVFLDLKKPSNHiYIKENEVFPSASTIKVLIMAEALNEVL -SGNHALEEKIEIKSSDKVNYSIVTC-LTNKIYPLIDLLTLMIISSDNTASNILIDLL-TM -DSINNYGKKIGLKTTLLRRKMMDSNAA-KEGRENITTAFDMLTLFSKIYNKKILSPDMCD -LMLKILSNNTD-CEVLLRYLCDDIRCAHKTGDLPH-LNHDIGIFRTENA-EYILGVFVRS -VQFN-YEAKDTIGKISKEIH--- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA1(2017) TaxID=1932113 RepID=UPI0009FB6293 ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALEMKPDQLERDLDEAYRRYYETGLNSATLVAYGQLFGKLAKGELLSEASTR -ALYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA -LDED-AEAGKLFEEVGEAI---- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium marinum TaxID=104 RepID=UPI0011EFC87A ---SAQQSLKAYLKTIDNKVSLYIIQNKQGKILsMSNSDKIIPSASIIKVPLLIYFMQKAS -EGTFSLQDHYHLKVEDKVGGSGELQFKPAGIVTYEYLAKEMIRVSDNTATNIIIKKL-GL -KAFQKWMKENDYSATQLNRFMMDFD-AIEKGKQNYCSSKEINRLLLALYNGNLLAENPSL -KVIEWLKNCED-NTGLPHLLPDRVAIAHKTGTLDY-VRGDAGIIFG--EKPIFITVLVEN -FS-EIAEADSIISTIGRLAYLEy ->[subseq from] Beta-lactamase n=1 Tax=Halomonas campaniensis TaxID=213554 RepID=A0A2D0AXX3_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVNDTFTQPDYDHAFDAYEATGENVGTLRAYGDLLASLQQGRALDAEQRQ -ALLEIMQRTSSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAERGNAGPWVIVSCTRG -PVA-VSAHERALTSVGEA----- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus nitrificans TaxID=651560 RepID=A0A3M8CTW8_9BACL ----LREKVTQLLDKAEGSWGVVVEDLDRGQCF-AHRREEAFIAESVMKVPIMAAVYAAAA -QGEFQLDDRISMRAEDQVGGSGILFALSPGLLTIREWVTLMIIQSDNTATNVLIDLV-GK -QRIEQTLIELGMERSKYSRKLMIYPVG--VTENNMITAGDVSRMLGAIATGRFLSHRACE -EMVAIMKRQQV-LNGLPSLLPPDWEIACKSGWDS-GRQHDVGVFYTEGR-RFSIVALSQD -VQ--SQSALRVLGQIGKEVYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Collinsella sp. 4_8_47FAA TaxID=742722 RepID=A0A096KQ88_9ACTN ---AIQQDIEALAEPYSGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALEAVT -AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTQTVLARLMMDAEAQ-AQGHENYTSARDAAVVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Propionispira arboris TaxID=84035 RepID=A0A1H7B0V3_9FIRM ----LSKQVSTIPIEKDVKYAVYIKNLKVDDKA-VVLNSHKMASASLIKIPIMIEAFNQKN -QGKLNFNEQIVIKHAQAVEGGSVYNLPDGTVLTVGQILDLMIVQSDNTAANILIDKL-KM -ENINAMIQKLGCKDTILQRKMMDFEA-VKQGRQNYTSVTDMANILGKLYNSQCLDPESDK -AMLAIMLQQED-NTVIPAQIPHDLKIAHKTGELD-GMYYDCGIIYGHSSD-YILCIMAEN -VKD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus deserti TaxID=673318 RepID=A0A2N5M2G8_9BACI ----LEELLKAHLTLTSGRISLALEI--QGEKF-EYNSRTIIPSASLIKLPILIAAYRESE -KGKLFLHRRVTVTREDKTGGSGVIQSLSEGLFTIKDLLTLMITVSDNTATNVCIDLI-GL -DSINDTIKEIGLRHTVLGRKMMDWDG-IKEGKNNYTSANDMLLCMKAINEQGILTEESRT -DILNILQSQQF-VDKLPAHMDTDITIANKTGELP-GAEHDTAIIKFKEKT-AYAAVLTDG -L-LSQEEGRQAIRNIGHIIYNH- ->[subseq from] serine hydrolase n=1 Tax=Collinsella sp. 4_8_47FAA TaxID=742722 RepID=UPI000A06A52B ---AIQQDIEALAEPYSGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALEAVT -AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTQTVLARLMMDAEAQ-AQGHENYTSARDAAVVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=A0A4S2ENP7_9LACO -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI00138F47A7 -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6C1NXP4_9BACT ----------------NALFSVAVHDADGAELY-ARNAGRQVASASVIKIPILAELMRMVD -GNELSLDETYTMTSGDIVGGSGELQHAGPGGYTLEYLAREMIRVSDNTATNIIIRRI-GM -ERINRLMAELDMDQTVLARYMMDFQ-AIEEGRQNYTSAADMNRVLLAIMG---------- ------------------------------------------------------------- ------------------------ ->[subseq from] HGE-1 beta-lactamase n=1 Tax=Azospirillum sp. CAG:260 TaxID=1262706 RepID=R6I2E7_9PROT --------------GSGSRVGIAVLS---GDKV-LTVGKGAMPLMSVFKMFVALNVLEHQE ------KDKVLIVTEEMINRYSPMLKDYPVVPISVAELLKYMVSASDNNATDILLAFGGDI -RATQDYVRGLGFPGIVLKVNEQEMHENIRNQYLNRAVPADVVKLLRIVRESERLTNENKR -FFEALMTETATGADKIKKYLPSNVVVGHKTGSSDNGADNDVGFVRLPDGREYYLGVMIAD -SPMSDRDNAELIARISKIVYRHf ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. TaxID=1486246 RepID=A0A2G2L6B6_HALSX ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVNDTFTQPDYDHAFDAYEATGENVGTLRAYGDLLASLQQGRALDAEQRQ -TLLDVMERTSSGKQRLKAGLGSSISFAHKTGTQQR-RSCDAGIAERDNAGPWVIVSCTRG -PAA-VSAHERALTRVGEA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Laceyella sediminis TaxID=573074 RepID=A0A2T0YJD6_9BACL ----LIQNLEHWKGRAVGNWGVWIEDLTSATTW-AWNETKSFYAASIIKVPIMVAVYKQAF -LGRLALADEIILTAEDQVGGTGVLQHLSPGLLSVQDLTTLMIIQSDNTATNILIDLL-GT -ETIRETMDELGMRQSTFYNKLMIVPAEPA--GLNMITAADVARCFRHIAQGKAVSQHASR -QMVEILKKQQL-RDCFPTGLPSQWELAHKTGMVTR-TLHDAGILFTKSRA-VVMVALSEE -CE--YEQAQQQMKQLARLVYE-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0006D8A9C8 ---TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEDMMEDSDNTAANIVIRQLGGM -NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora violae TaxID=1278207 RepID=UPI00102BD6FB --------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQAFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWNAEILTPASRD -LMIQFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella sp. CAG:1031 TaxID=1262917 RepID=R5AQ20_9BACT --aELKKELTAIADSAKGDVGIALIY--DGDTL-TVNNDAIYPMMSVFKLHQAVALCRMFE -ENGTSLDSVMTLRRSELDPWSPMLKDHSDEELPMRRLLEYTLIESDNNASNEMFVRLMPP -AACDSVIAGIPRGSFEIRFNEAEMQADHSRAYSNRTSPLGAAILIDRVFTDTLVGKSYQD -FIKSALMRCQTGPDKISAALSEGITIGHKTGSGYRDASNDVAFISLPDRRHYALAVFVKD -FDGTDAEAAATIARISAAVIK-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UAI2_9BACT ----LTEQVERLTAESKARTAVSLHDLESGLRF-SLRGDRWFHAASTIKVAVLLALFRAVD -EGRVRLDDSLHVRNRFFSAGSPFQYQAIGRTAKISALAAGMITASSNLATNLLLDFL-GV -AYARNVLRDAQVQGVELRRGVEDH-AAHEKGINNEATADGLVTLLSAL-RGDFLRSESKE -RAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIIYLPEREPYIAVILTEF -DS-EKEGRRETVAAISEAIYH-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 1001175st1 A10 TaxID=2559709 RepID=UPI001106006A -------NVTDQIKALPGKTGFYYENLVTGERA-AYHEEERMMAASVIKLFVMTEAFTRFE -EGTLSPDRIIRMRREDCVPCGALTYLHDGIEVTVLDLVTLMIIFSDNTATNVLIDLL-GI -EEINRTIRRLGYRDTVLRRKMYDTEKS-KQGIQNYITAAETGRLLREMYQGRLVSRMASE -AMISILKNQQL-CSKIPQALPEEPEIAHKTGEDC-GITHDVGIIYAKQ--P-FIVCYCGN -DT-DTPAYERVMAETALWLY--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0013034B8B ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILIIAYQQVN -EGKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI0007C563BB --eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Beta-lactamase, putative n=1 Tax=Synechococcus sp. (strain ATCC 29403 / PCC 7335) TaxID=91464 RepID=B4WI30_SYNS7 ----LKAALQALPDQYTGVPKVFYADVDTGEYV-SVGGEEAIAAASTIKLPILLAFFEDVD -AGRIDLMKTMSMKPEQIASGSGDMQVDPKTQYTALEVASQMIVTSDNTATNMMIDLLGGP -EALNNRFINYGLETTQLNAPLPDLEGT------NLTSARDLAHTMLLISQGESLTVRSRD -HILNILNRTRS-KDLLPATLEKGALTYNKTGDIRS-VLGDIALVDLPNGKRYVVAALVQR -PSND-IRAAELIRQVSDRTY--- ->[subseq from] CubicO group peptidase, beta-lactamase class C family n=2 Tax=bacterium A37T11 TaxID=1855384 RepID=A0A1H8KI18_9BACT ----LRKRILAQTAKFKGHFAVAYKDLQTGETF-FLNEKDSFHAASTMKTPVMAEVFEQAD -KGKFSISDSVTVINKSIVDGSKYSYKLIGKKTTIDDLLQRMITRSSNLATNNLVNLV-GA -KNVMKMMKGIGAKDIKVLRGVEDSK-AYEKGLNNTTTAYDLMLIFEKMAQGTLVNKQSSD -AMIAILKNQYF-KSVIPARLPANVKVAHKTGGLPL-ICHDSGIVYLPDGRKYVLVLLSGD -VPV--EQAKK------------- ->[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013BE45F9 ---GVADRIRAVFADAGCTGWLHARRCGTTAEI-AVDGRDRVVTASVYKLVLFVAFCRRID -DGLIDPGARITVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADILLGEI-GL -GAVEELLAELGLTETRIVGGTADVHRAYDPSYASATTPEDMTRLLQLVWGGGVLSPEQTG -FVRAVMRKQVW-PHRIASAFPRGVFVAGKTGTIGV-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W1AUN1_9CHLR --eQLENTLKDKITIFDGVAGLAVKSLTSEKSI-SINGDEVFPTASTIKVHVLAKLFSLQE -EGKIDLSRRIRFTQDMYGAGSGVIHFLENDPFTFRDVAILMMLASDNTATNICIDIA-GM -EGINDLIRDMGLSKTRLRRKMMDPE-AITRGDENVSTPNDLILMMAQLHNGKP-NPKVSA -QVLQIMSKPKS--DYLNKAVGSEVVVANKPGAMGR-AQGDTGIVFLPNN-PYTVSIMSKF -SMVDSIAQEGFIIDLARTIH--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. M1575 TaxID=2486009 RepID=UPI000F7986A5 ---------------IGGTTSAYFYDLSSKQSA-TFGADKQQRAASDIKLFIMATVYQSVA -DGKFELNEKYALKDTDKVGGSGALQGMAAGTVSYQDLLKYMMTQSDNTASNILLDKVGGL -SAVNNEIKKLGLTNSVMQRKLMDTKK-LAAGQDNMTTAKDLGRFLTMLYHHQVVSETADS -EMMQLLSQNTN-HSKLPAQVASDVKVYNKTGEFGYGVQNDAAIMEKGGK-AFVVVVLSQN -GTEAT------------------ ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429BPR5_9ACTN --------FATLFRMAGVTGWLHVRDVDSGREA-GLGADQPVPLASVYKLPLLVEFCRQAD -AGRLDPTTQTTVTPDQRVSGPTGLSAMLDEVMSLRDLAYLMMTVSDNTSADVLLDRV-GM -DDVNTMLDAFGLTGTRVLQSGRAMYEVLDPARTNRSTPREMTRLLAMIWRDEAASPASCA -WMRAVLNMQVW-PHRLASGFPDDVEVGGKTGSLPT-LRNEVGLVEYPDGGRYAVAVFTRS -FGTAQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Propionispira raffinosivorans TaxID=86959 RepID=UPI0003A1895D ----LSKQVSTIPIEKNVKYAVYIKNLKVDDKA-VVLNSHKMASASLIKIPIMIEAFNQKN -QGKLNFNEQIVIKHAQAVEGGSVYNLPDGTVLTIGQILDLMIVQSDNTAANILIDKL-KM -ENINAMIQKLGCQDTILQRKMMDFEA-VKQGRQNYTSVTDMANILGKLYTSKCLDPASDK -AMLAIMLRQED-NTVIPAQIPHDLKIAHKTGELD-GMYYDCGIIYGHSSD-YILCIMAEN -VKD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. PA05 TaxID=2604466 RepID=A0A5D0PPH0_9ACTN -------AFDRLFRAAGVTGWLYAADIDTGHEI-GHGADDPMPTASMYKVPLLVTLARHAD -AGLLALTDRVTVTSHDRVSGPTGLSPMCDDVISLRDLAYLMIAVSDNTAADKLLAQV-GL -DAVNATVRELGLDGTRVVQSAREMNDALDPARANRSTARQMAELFGMIWRDEAATARSCA -WMRGVFNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRCESGVVEYPDGGRYAVSVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7TB95_9BACT ---ALAQRLAERIARAPARVGLYYRSLAGSDSL-LIGANLRFHAASTMKVPVMIQIFRDAD -AGLLRLDDSLTVHTASLVPAEAFIYESVGRNRSVRDLLELMITRSSNLATNILIERV-GA -VRAQASARALGAWSIQVLRGVEDGQ-AYRAGLNNTTTARDLGVLLIAIVQGRAASRPSCD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAAVVYPARGGPYVLTVLTGG -IKED-SVAHNLVADLSRLVY--- ->[subseq from] Serine hydrolase n=1 Tax=Collinsella sp. WCA1-178-WT-3 (M2) TaxID=2605780 RepID=A0A6A8M423_9ACTN ----LQQDIEALVEPYGGSTSVYAVALDLDGEV-AVAPDARHVAASIIKLPVLACALETVA -AGELSLDEQITVAQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQQLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIIYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Beta-lactamase family protein n=1 Tax=Micromonospora violae TaxID=1278207 RepID=A0A4Q7USB8_9ACTN --------------------GATVRDLSGDQQI-AVNGSLRPKAASVIKLWILVELLRRVD -CGQAFLDDGVLVTPQDVVGGTGQLQFETPQVVTLHRLAQYLIKYSDNVAANVLITYLGGF -APVNALIDSMNQRSTILARRMLDSAAA-QRGEENYTSPDDVVSLLGAVWNAEILTPASRD -LMIQFMREQTL-NTKIPAALPPGVPVAHKTGDLPD-ASHDVGYYLIPGTE-TAVAFLTAG -PM---ATGDETVRRMARTVYD-- ->[subseq from] Imipenem-hydrolyzing beta-lactamase n=1 Tax=Bythopirellula goksoyri TaxID=1400387 RepID=A0A5B9QF79_9BACT ---STEQRLVELAQSVPGTIGYHVALVN-GEVLySHLGDEAFPQASAIKIPLLMEVLAQRE -ERQLDWNALHPILAKHQVGGSGILSEFTDGGLNTADLCTLMIVLSDNTATNMLIDLV-GM -ESVNRRMDSLGLRKTRLNRLMMDTAAS-ARGEENVATPQEACRVMRLLAQGKFIDPEISN -ELLAMLRKPKS--TAIRKAIAAEIPVASKPGAIP-GVATEWAVVELPGQ-PYVMIFMGKE -GS--ENEFNQVFTEMAKCIH--- ->[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrio bacteriovorus TaxID=959 RepID=A0A161PRC4_BDEBC ------------------------------------------------------------- ------------------------------------------------------------- --RYEAFVKRIQVPTSELKATIEEAFEKYYARGLNSTSLRSFGSLLEKLSQGQILNKKHTE -LVLTYMQKMKTGENRLKAGLPNDILFAQKTGTQV-ARMCNVGIVTSKKNQQKTVIVACAE -KYLDQAGAEKALKKMADALTE-- ->[subseq from] serine hydrolase n=2 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI000F63C438 ---ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE -RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL -AAVNRVAAELVDARLRIT------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=2 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI000F63C438 ------------------------------------------------------------- ----------------------------------------------------------AGP -ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG -WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG -TG--TAAGVHALQRIAAAIT--- ->[subseq from] Serine hydrolase n=1 Tax=Microbispora sp. SCL1-1 TaxID=2592812 RepID=A0A544Y958_9ACTN ---------------AGVMGWLHVVDIDDGREV-GLRADEPVVLASVFKVALVLELHRQAE -RGLFDLTERVRVPGADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNTLLDGLGLTATRVTQDCREMLTALDPAVANRSTPREMTRLLSMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS -YGQNQPRADAAIGTAARMAIDQ- ->[subseq from] serine hydrolase n=1 Tax=Nocardia altamirensis TaxID=472158 RepID=UPI0008405C6E ---AAEQRIRAVFADAGCTGWLHARRTDAGAEI-SVDGRDRVVTASVYKLLLFVAFCRHVD -AGRIDATERLTILPSDCTPPTGIAALHDSVTMSLRDLATSMMTVSDNAAADVLLGQV-GL -GPVAALIDELGLAETRVVGGTADQHRAYDPSYTSASTPEEMTRFLRALWSGAVLSPEQTE -FVKSVMRKQVW-AHRIAAAFPSTVRVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPVVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HB88_9GAMM ---ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE -RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL -AAVNRVAAELVDARLRIT------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HB88_9GAMM ------------------------------------------------------------- ----------------------------------------------------------AGP -ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG -WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG -TG--TAAGVHALQRIAAAIT--- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides eggerthii 1_2_48FAA TaxID=665953 RepID=E5WV58_9BACE ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD -FKGNESQASQYVAHISEVVYS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC30_STAAU ---SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTL--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Azospirillum sp. 47_25 TaxID=1896971 RepID=A0A1Q6UCG3_9PROT --------------GSGSRVGIAVLS---GDKV-LTVGKGAMPLMSVFKMFVALNVLEHQE ------KDKVLIVTEEMINRYSPMLKDYPVVPISVAELLKYMVSASDNNATDILLALGGDI -RATQDYVRGLGFPGIVLKVNEQEMHENIRNQYLNRAVPADVVKLLRVVRESERLTNENKR -FFEALMTETATGADKIKKYLPSNVVVGHKTGSSDNGADNDVGFVRLPDGREYYLGVMIAD -SPMSDWDNAELIARISKIVYRHf ->[subseq from] serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=UPI0010597F42 -----------------HEISVAYLNLGSGSTF-FHNGKTVFHAASTMKTPVMFQLYYMHD -EGELSLEDSLVVRNESIVDGTPFSIENVGNNMTIRDLIEAMITTSSNLATNILIELA-DP -EAVMSTLKEVGAEGVSVIRGVEDLKA-FDQGLSNRTDAYGMMMAMKAVYESELVSDKSRE -EMIGILKRQEF-NEMIPAGLPLGTAVAHKTGWIT-GITHDAAIVMPRNDSPFVLVILTRG -WAVH-DSAVDAGVKISKSVYRY- ->[subseq from] Serine hydrolase n=1 Tax=Fictibacillus sp. S7 TaxID=2212476 RepID=A0A4V1QKL3_9BACI ---ELKNRVNGIIDPLNGEFAYYIET--EEGYI-GKNEEKVFPAASLIKLPILIEAFRQKE -AGLLDLSMPVHINQKDKVGGAGVMNHLSPGALTVLDVLTLMITVSDNTGANVMIEHA-GR -ERINALLTELQCDQTVLERKLMDFK-AIEAGKNNYTSAKDVVLLLKEIHHGKLLQNESRK -MMLDILRNQQF-RHKLPGSMDEAVIIANKTGELQ-GTEHDAAIFEYNGR-IIFAVVLTKN -LTREA-DARHKLAAVGTAIQ--- ->[subseq from] serine hydrolase n=1 Tax=Pricia antarctica TaxID=641691 RepID=UPI000B836E35 ----FEKTVLSQIDSIDGDVAVVFYTLSDPKDSlFINENEKFHAASTMKVPVMIELFKQAE -QGKIDLNDSILLKNESIVDGSSYSYGQIGSKVALRDLMYSMITVSSNLATNVLIELV-GA -KKVTGTMRDLGAENIEVLRGVEDQK-AYNQGLSNSTTAKDLLLIMEGIADGSAGTPEDCE -IMIAILKEQQF-NDIVPFYLPKNVSVAHKTGSIT-GVHHDTAIVFLPDGRSYILVLLSKN -LE-NFDKGTEQLAGISKTVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium GWC2_71_10 TaxID=1798309 RepID=A0A1G0LYZ5_9BACT ---------------------------------aAINADQRFHAASTMKVAVMVQVFRDVD -SGRLTLRQRIPVTNRSLVG--DTLYGHVGGAVEVERLVRLMITVSSNLATNILIEQV-GA -ARVQQTLADLGVDSMQVRRGVEDGP-AFRAGLNNSVTARSLGQLLTAIADGRVASAASCG -RMLRILLDQEF-RDAIPAGLPRRTRVAHKTGWIT-ALHHDAAIVYRDGHPRYVLVVLTRG -LA-EQRASSALIAELARAVH--- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3MIT5_9BURK ---RLQTELTRLDGNGRPTVGVYVRDLDTGEST-SYRAGQRWYIASMVKVPVAIAVLRGIE -RNQFTLDTNVTLRASDYVDGAGPTSRYAGTPLTVRFLLEQMMVLSDNTATDMLIDLV-GL -AEVNAVTQALVPEGFSHITTLGDVRRAYYAEGVNSAQLGAYGELLAKVVDGQALTPRWTA -YLLALMERVQTGTRRVKAGLPAGLRFAHKTGTQRY-RICDAGLVRTAAHQRRVLVVACAR -GDVPFERSEAALMQVGAAL---- ->[subseq from] serine hydrolase n=1 Tax=Microbispora sp. CSR-4 TaxID=2592813 RepID=UPI0011C8DDF5 ---------------AGVMGWLHVVDIDDGREV-GLRADEPVVLASVFKVALVLELHRQAE -RGLFDLTERVRVPGADRTGGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNTLLDGLGLTATRVTQDCREMLAALDPAVANRSTPREMTRLLSMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS -YGQNQPRADAAIGTAARMAIDQ- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Staphylococcaceae TaxID=90964 RepID=A0A317ZBE9_STAPS ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPK------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Aneurinibacillus migulanus TaxID=47500 RepID=A0A0M0H215_ANEMI --qRLREDVERMVSKVDGKVSVAIE-TDKGHIL--INANDPLPSASLIKVPIMIEAYRQVQ -EGKLNLASKYSLLPEDRVGGMGIVSHLSPELLTLKDLISLMIIISDNTATNAVIRNV-GI -HTVNQLATDLNCGQTVLARMMMDHE-AVKLGKDNITSANDIVRFLKEIVEGSILNEENKK -AAYNTLLNQQF-NTKLPAGFSLNATLAHKTGELP-GTEHDAGVFHINGK-HAYVAVLTTE -LS-DNTSGQRIIAQVGKLVFDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Pricia antarctica TaxID=641691 RepID=A0A1G7ECS8_9FLAO ----FEKTVLSQIDSIDGDVAVVFYTLSDPKDSlFINENEKFHAASTMKVPVMIELFKQAE -QGKIDLNDSILLKNESIVDGSSYSYGQIGSKVALRDLMYSMITVSSNLATNVLIELV-GA -KKVTGTMRDLGAENIEVLRGVEDQK-AYNQGLSNSTTAKDLLLIMEGIADGSAGTPEDCE -IMIAILKEQQF-NDIVPFYLPKNVSVAHKTGSIT-GVHHDTAIVFLPDGRSYILVLLSKN -LE-NFDKGTEQLAGISKTVYDY- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium TaxID=28453 RepID=UPI000FBABD5A --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFNKIE -KGELQLDQQLLYRASQQYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -VAINKLMSDLQLAHTRVNSQTEGRKPDWERYGWGQTTPKEMADLVTLIRQGKVVSPKSSD -QMYRFMGNMFY-DERGLSQIPSTVKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEVLTRKLSKLLWDYy ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5VUX0_9BURK ---RLVHDLARVSAGHSAGIGVYVRDLETGVAA-RFQSSESWYLASTVKVPVAIAVLRGVE -RGQYKLDTTVTLEASDYVDGAGLTNRNPVGSLTIRYLIDQMIVYSDNTASDMLIGLV-GV -DELNALVRELVPEGFGRITRLAEVRRAYYASGLNSARLDAYGELLARLAQGQALAPASTD -YLLRVMERVATGTHRIKAGLPPAVAFAHKTGTQRR-RFCDAGITY--------------- ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides eggerthii TaxID=28111 RepID=E5X1E3_9BACE -----TDTISKIVAYYPGEIGVAVI-INNTDTI-TVNNKSIYPMMSVFKVHQALAICDDFG -HKGFSLDSLMTIHRDELDPWSPMMKEHLEPVLRVKDLLCYTLILSDNNASNFMFKKLVNI -TQTDSFIATIPRLSFQIAYTEEEMSADHDKAYANYTSPLGAAILMNRLFTDSLIDYDKQQ -FIIKTLEQCSTGKDRIAAPLKDGITIAHKTGSGYTNAHNDVAYIRLPNGICYTLAVFVKD -FKGNETQAAKAIAHISAIVYS-- ->[subseq from] serine hydrolase n=1 Tax=Halomonas sp. TG39a TaxID=1415755 RepID=UPI00068A366F ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ -TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG -PLA-VSAHERALASVGEA----- ->[subseq from] serine hydrolase n=1 Tax=Halomonas TaxID=2745 RepID=UPI000682A860 ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ -TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG -PLA-VSAHERALASVGEA----- ->[subseq from] serine hydrolase n=1 Tax=Nocardia shimofusensis TaxID=228596 RepID=UPI000A070EA7 ---AAADRIREVFADAGCTGWLHARRCGGEAEI-SVGGHARVVTASVYKLVLFVAFCRGVD -AGLIDPADRLTIDPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEV-GL -GAVEEVLTDLGLTETRIVGGTADVHRAYDPAYTSATTPEEMTRLLRVLWSGTVLSPGQTA -FVRAVMAKQVW-PHRIAAAFPRGVTVAGKTGTIGV-IRNEVAVVEFPREYPIAVAVFTRA -ARADLPVVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A5Q0DQT1_ALCFA --qRLQERLEPLLSQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAILPSVARLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536FFR3_9CHLR ---------RERLSSLPGEAAAYVSDASGRELF-SERADEPFPAASVIKLPLVMAIFADAA -RGRVDLDERVAVGE--RVDGSGVLRHMRDVELSLRDLAMLAVIVSDNTATNRLIDRI-GV -ERVNERLREWGCPNTRLARRMYDFAAA-ERGAENLMTARETASLLVRLVRGECEDRATSD -AVVALLAECQD-RTMLRRYLPNAADVANKTGTLDE-SRNDAAIVRGE--PTVVVAAFTRK -LRDTE------------------ ->[subseq from] serine hydrolase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI000258B24D ---TIQGTIDDAFGDMQGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFISITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEEMMEDSDNTAANIVIRQLGGM -NKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI0013A0866E -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTRS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI00129839B4 -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTRS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0AIM8_9BACT --tALQAKIEALAAQHHGKLTLYASNLKTGATV-AIESDKPVATASVIKLPILVEAMGQVK -AGKRRLSEKITLQKDDIVQGSGILQFFDIPLITLKDALTFMIVESDNTATNLVMDQI-GM -KNVNDRIASMGLKDTYLYKKVPTMPADQKRFGLGKTTAKEMAKVMESIVRCDLKDQELCD -DMLYMLRNQQY-RNLVPHYIETSSLIANKTGSLDE-VRNDVAVVYSKNG-PILISAFTYD -NQNNENAAELLIAHIAKLILETw ->[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A519FQB1_9BURK ------------------------------------------------------------- -----------------------------------------------------------GA -QRVEALRSALGVPRASLKRTIDEAYARYYEKQLNAATLEGYGAMLEKLVQGKLLKPASME -RLFTDMKIRIFTNYRLQAGLPRSASFIHKTGTQYR-RACHAGVINPQDGAKAIVVATCAA -DIDEQKDAGKVFEQVGRAITR-- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI000D882CA3 ------------------------------------------------------------- ------------------------------------------------------------P -ARVTAFARQRADEPVHVDRTKPTLNTAIPGVPHDTTSPRAMAQTLRNLTLGKALGDSQRA -QLVTWMKGNTTGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQ -PQPKAESRRDVLASAAKIVTD-- ->[subseq from] Beta-lactamase BRO-1 n=1 Tax=Halomonas sp. R57-5 TaxID=1610576 RepID=A0A0D6E4R6_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -----ALARALGVSTESFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHHGRALDAEQRQ -TLLALMQRTRSGKQRLKAGLGSGISFAHKTGTQQR-RSCDAGIAESDTEGPWVIVSCTRG -PLA-VSAHERALASVGEA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. OV166 TaxID=1882763 RepID=A0A1Y6FU89_9BACI --dQLKVRIEEELRGLSGRVGLAVEI--EGESL-YVNCEETFQSASLIKVPILIEAFRQSE -AGKLNLNQLVSITN--HVGGSGVLQAFSRDALTLKDLMTLMITVSDNTATNMLIDKL-VM -ADINRSIKKMGLKHTILNRKMMDFA-AIGQGHDNFTIPIDMLTCLKAVNEGSYLKEESRA -AVLKIMSYQQF-QDRLPGLMDERVVVANKTGSLPR-VENDCAVIKYKGKT-AYAAVLIDR -LD-DVYAGKQKISKIGKHIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=A0A4Y9HTK0_9LACO -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTIDLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6K129_9BACT ----LNEELERLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVVVLLAIFRAAD -EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTTKISALAEGMIASSSNLATNLLLDFL-GV -EYARNVLRDAGVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGDFLNSDSKE -QAIRILLQQRF-RSMIPARLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EQDGRRETVAAISEAIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=A0A235DWA8_9SPHI --kKLAAKINQAIEGFQGDVGIYVKHLKQNKEV-NINADSIFPTASVVKVPILVGVFQKIK -DGELRLDQKFLYRDSRAYGGSGLMQFFKDSTTDLSTLIGLMLSYSDNVTSIWCQELAGGG -QAINPIMDQLGLTNTKVNSRTVGREDIWKKYGWGQTTPKEMANLYEFIRNGKVVSPAHSD -KMYRFLKNQFY-NERSLSQFPAEISTIDKTGSLDE-SRNEVVLVNAPHGD-FIFSIFTNN -NKTKSNAAENLTKKIANIIWNHy ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium cellulitidis TaxID=1768011 RepID=UPI000B93DA07 --kKLAAKINQAIEGFQGDVGIYVKHLKQNKEV-NINADSIFPTASVVKVPILVGVFQKIK -DGELRLDQKFLYRDSRAYGGSGLMQFFKDSTTDLSTLIGLMLSYSDNVTSIWCQELAGGG -QAINPIMDQLGLTNTKVNSRTVGREDIWKKYGWGQTTPKEMANLYEFIRNGKVVSPAHSD -KMYRFLKNQFY-NERSLSQFPAEISTIDKTGSLDE-SRNEVVLVNAPHGD-FIFSIFTNN -NKTKSNAAENLTKKIANIIWNHy ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C1YUI7_9BACT ---ELKLSIDSIIVTHKGTFAVSFKDISTGVRV-DINAHEYFHAASTMKTPVMIEVFNQAK -QNKFALNDSIPVVNSSIIDGTEYSYNRIGKLETIRNLVVKMITVSSNLSTNILIEKV-GP -ENVMRTLATMGLKDIQVLRGVEDGK-AYDAGKNNTTTSFDLSIIYESIALKKCISKQASE -EMLEILLSQKF-KDMIPAKLPPPVKVAHKTGSITN-VQHDSGIIFLPDGRSYILVVLSKN -LA-SNKEGIEAISSISKRIYD-- ->[subseq from] hypothetical protein n=1 Tax=Collinsella sp. AF31-11 TaxID=2292011 RepID=UPI001314406D ----LQQDVEALVEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT -AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANFVIGRL-GM -DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Gastranaerophilales bacterium TaxID=2137880 RepID=A0A316P627_9BACT ----LENQLENLAALYSIEPAVFVWDYETGNYA-GINSDKLYSAASIIKIPVLIQLFRSIE -AGQLTIYDTMKLTDYYRAEGSGSLQFKAENSWTIDDLARIMITESDNSATNMIMAKLGSM -TDVNSGIRQWGLSKTRVNTWLPDMGGT------NFTTAEDLGRMLYNLDNPNFLSMSSRE -KIFDYMGHVHN-DRLIPAGLGAGAVFLHKTGDIGK-MLGDAGIVYAPNGKKYIVAILANR -PYN-SPLGKDYIVKASEIIYNY- ->[subseq from] serine hydrolase n=2 Tax=Staphylococcus TaxID=1279 RepID=UPI0013F690C7 ------------------------------------------------------------- -------------------------------------LIEASMTYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Serine hydrolase n=2 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GRH1_9BACT --pTLEQNLTDYLAKLSVKVNYRVESLEGKPYA-SLGDDERVPSASIIKIPILVEVMEQVK -AQRFELTDYYTLQNTDKVGGAGIFQEREGKAFTYEQLAHQMMVASDNTATNILIRKV-GR -EAVNERMKTLGFSNLQLNRVMMDTAA-VAKGIENYVNATEINRLLSLIYQRKVATPALCD -LMVAFLLDNQD-TSTLPSLIPRQVGIAHKTGTLTY-IRGDAGIIFTK--KPFVISIFVRG -AD--LSRAETIIAEIGKIGYE-- ->[subseq from] Serine hydrolase n=1 Tax=Collinsella sp. AF31-11 TaxID=2292011 RepID=A0A415UYM1_9ACTN ----LQQDVEALVEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT -AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANFVIGRL-GM -DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sphingobium sp. TaxID=1912891 RepID=A0A2D8TCZ0_9SPHN ---------KEIEEETGGRLGVALVDRQGALLL-GFNRDERFAMCSTFKAPLAAAVLTGAD -GGKFGLEGTIPFGKDDVLDYAPVVKKNLKRGMSMEELARAAVEVSDNSAANLLLPMLGGP -EGLTAFMRVHGDDVTRLDRTEPALNENAEGDPRDTTT----------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Porphyromonas sp. COT-239 OH1446 TaxID=1515613 RepID=A0A0A2E0J7_9PORP ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD -FKGNESQASQYVAHISEVVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Trueperaceae bacterium TaxID=2026798 RepID=A0A5Q4G4S4_9DEIN ---TLESRIDHLVAPLPGVTGVVVWRPHDQAPLlTRHADRTFALASVVKLPLLLETLRRAE -RGALDMGERVRLDEADRVAGSGVLHLLDGGLPTLRDLLRLALVVSDNMATDALFARV-PP -SAVETAMHALGYTSLRVPHTIEAMLRA-SPTRGDRATPLDVARMLVDLHAGRVLGGPWRA -LALTILGDCQT-NGRIPARLPEGTRVAHKTGTLRS-RTNDVGIVATPAG-PVVLALFQEG -EP-SERRASAALADVALAVYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. KNHs216 TaxID=1550235 RepID=A0A542ANK4_9CLOT -------KILDILNGIPGKTGFYYKNLTTGEKW-EVRSEEPMIAASVIKIPVLAEVFAQLE -AGTADKNELYRIREEDKLPSCGALNMHTGLEVTLEDLYTLMIILSDNTATNLLIKKF-GM -ENINRRMRGLGLNVTTVNRLLFDAGAS-AAGRENRICAKEIGLLLEKMYRGELISPKASQ -EIISILMNQRL-NGKMPFHFKGKVKIAHKTGEDG-GITHDVGIVFAPQ--PFVTCFCSNE -T--DVPLFERAIQDITKLLYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7ZQ35_9BACT --qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK -AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTVKDLITLMVIVSDNTATEVLYRMVGGI -DAVNRRMDAMGLKSTRAMSLPTAWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD -LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN -HFGSGEALENAIGLVAKEVADYy ->[subseq from] Beta-lactamase (Fragment) n=4 Tax=Staphylococcus aureus TaxID=1280 RepID=E0XCT9_STAAU ---------------------------------------------STSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNTVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKS------------------------------ ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Staphylococcus aureus TaxID=1280 RepID=Q6UIU7_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFG------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A3D2M9J5_PSESP ------------------------------------------------------------- ------------------------------------------------------------- -----AVANALSLSKSELKASMEQAYERYYARNLNSSTLEAYGTLLENLVEGELLSESSRD -LLFKDMKIDRYDGYRLEAGLPSDVPFIQKTGTQLE-RACHVGVIDPEQQATTVIVVACAE -ALDEAKEAGAAFEQVGEAIT--- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus tyrfis TaxID=1501230 RepID=A0A081NXT7_9BACL --tQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ -EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM -GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVDGSTLKQEAKD -AALQLLRNQQF-NAKLPARMIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD -LV-DNLPAQQVISTIGKAVFDY- ->[subseq from] serine hydrolase n=1 Tax=Sediminibacterium roseum TaxID=1978412 RepID=UPI00137B4421 --kKLESQLNELLKGFNGNMGIYVHDLKKNRIA-AINADTVYPTASMVKVPILAGIMRKIE -DGELQYHQTLTYKDSLLYAGVDILGSFKNGEIELSKVMMLMLTMSDNTASLWLQTLAGTG -TRINQLMDSLGLRETRVNSRTPGREAFRTQNGWGQTTPREMALLMEKIVNKEVVSPSASE -RMLRILGRNYW-DENAISQIPADVFVASKSGAVD-ATRNEVLFVNSKKN-PYIFCICSKN -NKEETNEAWVLTRKVSDLLWKYf ->[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium UBA9857 TaxID=2060923 RepID=A0A3B9QDU8_9FIRM ---ECKDQLIEIIKPAGGEWGIVIDALDGEDSI-HLNPEDPFRAASVIKIPIMMAAFHEAR -EGRIRLDDTIILRNQDKVGGCGVLKEHSGLEITLLDAINLMIVVSDNTATNLVIDAV-GK -DLINRYMETKGCTGSWLESQLMR---PKPRGPWNTITAKDIAMLLRGLAERTIENPGDCD -SMVGIMRRQQY-RQKLPRYLPKEAICANKTGEQT-GVTHDAGIITGPKCS-FVIVCLSQN -LD-DTDVGIEVISETAKWAYD-- ->[subseq from] Serine hydrolase n=1 Tax=Lacinutrix sp. CAU 1491 TaxID=2565367 RepID=A0A4U0EQF9_9FLAO ----LKTDITQQINTIEGNVAVAFLDLSNEENSiLINVDEEFHAASTMKVPVMIELYKQQN -QGLINLKDSIVLINKSIVDGSPYKYSKIGTKQTLYDLMVPMITVSSNLATNVLIEIV-DA -KKTTQTMRDLGAEKIDVLRGVEDIK-AYEQGLSNSTTARDLMVIMKAIANGTAGTKADCE -AMLSILKDQQW-NDMIPKYIPDNVEVAHKTGSIT-GVHHDAAIVYPPNGKTYVLVLLSKN -LK-DFDEGTDKLARISERIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8UI73_9BACT ---PLQDKLRARIAEFPGTVSLYAKNLDTGTAV-GIRESDPVRTASTIKLPIMMAVFDAVD -RRQATWTEPLTVTAAEKVGGTGIIGSEISDGLPLRDVIHLMIVISDNTATNMILERF-PA -DAVNAYLDKIGIRTTRALRRMRDDESQNQEYGLGVSTPRDMVTILEKLQRGEIVNADASR -EMIAILRRCRD-DSGIRRRLR-GISVANKTGSNNS-FRSDVGIAYSNNG-PIAMAISVGG -ISTPDNVGCLLIADLAKMLVD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=UPI0009F51416 ------------------------------------------------------------- -----------------------------------------------------------GP -KRVEAVANALDMKADQLERDLDEAYRRYYETGVNSATLVAYGQLFGKLAKGELLSDASTE -RLYDIMGLGGYEAYRLEAGLSEQLPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA -LDED-AEAGKLFEQVGEAI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas indica TaxID=137658 RepID=A0A1G9IQ24_9PSED ---RLLEELSRIDTDYPGEIGVFAKDLDSGLSI-SFRGEETWYLASGIKVPVAIAVLRGVE -RGEFTLDDRLRLEAYDYVDGAGETNRHPPGALGVRFLLEQMVIHSDNSASDRLIRLV-GI -EAVNRVVEELAPGGFQPITPLADVRRAYYATQLNSARLSAYGELLEALANGKALGAEGSA -HLMGLMERVATGRKRIKAGLPTVAAFLHKTGTQR-ARFCDLGIVRTADGDKRLIVAACTR -GDSSLARSETALRLVGQAVWQ-- ->[subseq from] serine hydrolase n=1 Tax=Rhodohalobacter halophilus TaxID=1812810 RepID=UPI00083F6A04 ---QLKSDNENHIAEEEGTFGIWFQHLQNPDLHfSINADTLFHAASTMKTPVMIELFRRAE -AGEFDLSDSIEVENKSIVDGSEFQERRVGEMATLYDLNHAMITYSSNLTTNLLIRLV-GA -EETTQTMREMGAENIQVLRGVEDLKA-FEQGLSNRTTPRDLGIIFEHIANGTAVSPTMDS -LMVEVLKDQFY-NDVIPAQLPGDVVTANKTGFIT-GVRHDSAIVYLPDGQSYVLIYLSKN -LP-DGDRGTEIGAEISKMIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WOR-1 bacterium RIFOXYC2_FULL_46_14 TaxID=1802587 RepID=A0A1F4U764_9BACT ---ALQGKLLQLTAPHKGKIGIYFLDMNSTFEA-QVYGFNAFPAASTIKLPIMAAAYHLKE -QGKINLGKMVVLRQNDKLGGSGVLQWRKPGLYSLLSLIGYMISFSDNTATKMVEDSV-GL -ASINNYLSSIGMLKTRVTN--PTMLSEPPDPNVNMTTPYEMAYLAAKIAKRSGFNDESAS -DMLYFMHNQRY-KWGIWKGVPPGTYVANKTGNLSR-ILNDVGIVNTKSGA-YVLSIFTWG -FS-SQHNARVLINNVSRVVYEEy ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas sp. PA27(2017) TaxID=1932112 RepID=A0A1Q9Y9K6_9PSED ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALKMKPDQLERDLDEAYRRYYETGLNGATLVAYGQLFGKLAKGELLSEASTR -LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA -LDED-AEAGKLFEEVGEAI---- ->[subseq from] Serine hydrolase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=A0A2T6FS81_9BACL --nQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ -EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM -GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVDGSTLKQEAKD -AALQLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD -LV-DNLPAQQVISTIGKAVFDY- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium BR5-29 TaxID=2607284 RepID=A0A5J5IIN4_9BACT --kNLQAKIKDLLKGFHGEVGVYVHDLKKNKTV-SINADSIFPTASMIKIPILIGIMDKIE -KGELQYHQPLIYKDSLLYAGEDILGSFKNDEIEMSKVMMLMLTMSDNTASLWLQTLAGTG -TRINELMDSLGMKVTRVNSRTPGRQANQAGYGWGQTTPYEMATLMGKIVKGDIINKEASA -KMLRLLGRNYW-DEEAISQIPTDVFIASKSGAVDE-SRNEVLFVNGKHC-RYIFCICTNH -NQEHNNEAWELTRKLSKMLWSRy ->[subseq from] hypothetical protein n=1 Tax=Geobacillus sp. (strain Y412MC10) TaxID=481743 RepID=UPI0011AB7135 ----------QQAEKNGIRMSVGIRDLSGHETL-LLGSREPYMPASTIKLAVVSALMQQVD -RGELSLADQVTVTPEDVVGGSGSLQTSFPQNLTLERLARLMITQSDNTATNVLIDKV-GM -DNVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENTN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. CGMCC 1.16541 TaxID=2185143 RepID=UPI000D7376D1 ---SLEERIQTVIDKCRGRVSVAIDMC--PHSI-TIHADTTYSAASLIKVPILLEGYRQVQ -QGVIDLEELVTVPQKDKVGGAGVLTSLSDAALTIKDLLTLMIIVSDNTATNLLIDRL-TQ -QSIHELCRQLDLQHTSLQRKLMDFE-AITKGLDNLTSASDMVKCLKMIDKSQVFEKENRD -RMLHTLQQQQF-YDKLPAKMNRDVSIANKTGELP-GVEHDCAIVHYKDQT-VYVAVLIDE -LD-DNYEGRQIITEIGHLLYTY- ->[subseq from] Beta-lactamase class A n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=A0A023X0W1_9ACTN ------------------------------------------------------------- --------------------------------GTVRSLSGAMISDSDNVATNLLVDRL-GF -ERINAAAQDLGLKETRLERHMLDFDAQ-AAGRENYTSARDTAALLAEIWHGRTLSPESRE -LALSTLELQTR-RAKIPAALPAGTRVANKTGELP-GVEHDAAIVLVPDRS-FVLVTLTSG -DPDS---GVEAIHA--------- ->[subseq from] Beta-lactamase n=8 Tax=Bacteroidetes TaxID=976 RepID=A0A5M5D4U5_BACOV ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD -FKGNESQASQYVAHISEVVYS-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI000B5C69D8 -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYHELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENENGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus enclensis TaxID=1017270 RepID=A0A0V8J1G5_9BACI ---ELKNRVNGIIDPLNGEFAYYIET--EEGYI-GKNEEKVFPAASLIKLPILIEAFRQKE -AGLLDLSVPVHINQKDKVGGAGVMNHLSPGALTVLDVLTLMITVSDNTGANVMIEHA-GR -ERINALLTELQCDQTVLERKLMDFK-AIEAGKNNYTSAKDVVLLLKEIHHGKLLQNESRK -MMLDILRNQQF-RHKLPGSMDEAVIIANKTGELQ-GTEHDAAIFEYNGR-IIFAVVLTKN -LTREA-DARHKLAAVGTAIQ--- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=C2Q4I5_BACMY ------------------------------------------------------------- -----KLDKVNTYIKDDLVEYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNILFKKLDGP -KGFEKELGQNGNKVTLADCFELDMKEAIQGDICDTSTAKTLAFNLKALTVRNALQTDKRK -IPTDWMRGNATGDELIHAGVPKDWEVDDKSGAGSYGTPNDIAIV---------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Lentibacillus halodurans TaxID=237679 RepID=A0A1I0W4M4_9BACI --nQLETEVHSIISGIDAPIGLVIKE--RNHSI-NVNENMPMPAASVIKIPIIMEAFRQAE -IGDLILSETLNIPAEAKVGGSGVLQTMSKDVITLLDVLTLMITVSDNTASNLALERV-GI -SNVNRLCRELEHHNTEIQRYFMDTKAA-EKGLENMTTAIDMVNFLEEIASPQLLNQDSAN -RILQIMSQQQLTSKLPAYHIIDDVMIANKTGELVN-AEHDVAIFQYKGR-TLFAAVMVNE -VS-DQVEAQQTIANIGKEVMAY- ->[subseq from] hypothetical protein n=1 Tax=Geobacillus sp. (strain Y412MC10) TaxID=481743 RepID=UPI0011A51C22 ------------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD -RGELSLADQVTVTPEDVVGGSGSLQTSFPQNLTLERLARLMITQSDNTATNVLIDKV-GM -DNVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENTN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas sp. PA27(2017) TaxID=1932112 RepID=UPI0009F83DB8 ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALKMKPDQLERDLDEAYRRYYETGLNGATLVAYGQLFGKLAKGELLSEASTR -LLYDIMGLDSYEAYRLEAGLSEQVPFVQKTGTQQH-RACHMGIANPQGDDALVILACAEA -LDED-AEAGKLFEEVGEAI---- ->[subseq from] Serine hydrolase n=2 Tax=Lactobacillus TaxID=1578 RepID=A0A358LUP3_9LACO -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Aminicenantes bacterium TaxID=2052149 RepID=A0A3N5SPW1_9BACT ---ELEQAVAAQAGKIKGRTGVFIKHVESGETV-GLRDGERFQLASVFKIPVLMTLHKEIR -LGRISLDDRIMFEERMKTYGSGLMTSMKPGLISVQDLQLLMMAKSDNTATDILFDLV-TP -EAVGATIAGLGLKDTTVDYNTRQLILTFDASTHDTSTPRDIATLLEKCVKGEFVDRETGD -RVLETMKHH-TGAELILRYLPESTDVARKGGSLGRGVLNDCAVVWLPEKGTLIICFFGND -LREIHYEIKHKVGLMARAAYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Pseudohongiella spirulinae TaxID=1249552 RepID=A0A0S2KGK2_9GAMM ----LRETLQQAGDGIRVSVGVSALEGGSGATL-LMGDALSYAPASTIKMLLVASLMQQVD -AGLLTLQQTTTVSPADVVGGYGVLQEEAQPQVTLGRLAELTVTISDNTATNVLVDVV-GY -PAMAGLAAQLGLELMHFGRKMFEAPE--PPAKDNYINAPDALALLTAIYSGTLLSDDSRD -QIMRWLSAQTV-RTKIAAGVPDGVKVAHKTGENGP-VSHDIGFIMLPDST-LAVAIFTEN -LKASQALLNPLVAEITSTIYRH- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus animalis TaxID=1605 RepID=A0A4P8K6F6_9LACO --------------------TVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNNEEQ---------------- ->[subseq from] Uncharacterized protein n=1 Tax=Globicatella sp. HMSC072A10 TaxID=1739315 RepID=A0A1E8YZ06_9LACT -----------------GEYSLYYQALDTSSQP-LILNNQPMRSASIIKLFVLAALFEQVE -KGELDLTEQYSLKAEDKVSGTGDIQNMEDGSLTLLTLAEKMMTISDNSATNILINLMGGI -EKVQKIIIELGYSDVQLKRLMVDLE-ALNAGNDNYVTAEDVGRILADIYQGKLVSKSASQ -EMLAILKQQTD-RRMLAQNLPSDVAYYGKTGNFDYGVQNDAAIIETPKGA-FILVFLSQE -GQ--KEQQLKAMNQLGKIVSEQf ->[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter sp. SW132 TaxID=2293433 RepID=A0A371QT08_9BACT ---ELRDSIESILDNEEGTYAVYFSDLDDSQIElTINPDTLFHAASTMKTPVMIEVFRRAD -AGEFSVYDSIRIDNRSIVDGSEFSERMEGEMATIYDLTNAMITYSSNITTNLMIDLV-GA -EETTRTMRELGAENIEVLRGVYDMKA-FEQNLSNRTTARDLAIIFRSIADGTAADRESGQ -LMIDILSDQFY-RDIIPKYLPEELIIANKTGSIS-GVEHDSGIVYLPDGRSYLLIYL-SK -NVPDDEHSRDVGARISELIYDFy ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas fulva TaxID=47880 RepID=UPI0005ACC3DE ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANVLDLQTDQLESDLDEAYSRYYDSGLNSATLVAYGQLLGKLATGDLLNGDSSA -LLYDIMGLGGYDAYRLEAGLNEDLPFIQKTGTQQH-RACHMGIANPQDERALVIVACAED -LDE-NDEAGTLFEQVGEAI---- ->[subseq from] Beta-lactamase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=A0A381K4Z3_9ACTN ----LQQDIEALVEPYDGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT -AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYGIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTQTVLARLMMDTEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0004CDAB9E ------------FRAAGVTGFLHAVDLDTGAEV-AHGADEPVVMASVFKLALLVEFFRQTD -AGRLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLVGRV-GL -SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTNRSTPRDMTRLLGMVWRDEAASAASCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066CD5EA -------DLEALFRAAGVRGWLLAADIDTGREI-GHGADEPVPTASMFKVPLMVEFCRQAD -AGLLDPASRVTVTGADRVGGPTGLSAMLDDVISLRDLAYLMIAVSDNTAADVLLARV-GM -EAVNAMLDGFGLTGTRVLQSAGETNSVLDPPRTNHSTARELARLFGLIWRDEAASPSSCA -WMRGVLNLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRGEAGVVEYPDGGRYAVAVCTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=UPI00068A3012 ------------------------------------------------------------- --------------------------------GTVRSLSGAMISDSDNVATNLLVDRL-GF -ERINAAAQDLGLKETRLERHMLDFDAQ-AAGRENYTSARDTAALLAEIWHGRTLSPESRE -LALSTLELQTR-RAKIPAALPAGTRVANKTGELP-GVEHDAAIVLVPDRS-FVLVTLTSG -DPDS---GVEAIHA--------- ->[subseq from] Beta-lactamase n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=A0A1Y0VX55_PEDPE ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNGKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5YW28_9BACT ---TLTEEVERLAAESKARTAVSVHDLESGLRF-SLRGDRWFHAASTIKVGVLLALFRAVD -EGRVRLDDSLHVRNHFFSAGSAFQYQAIGRTAKIAALAAGMITASSNLATNLLLDFL-GV -AYARNVLRDAQVQGVELRRGVED-HAAHEKSINNEATADGLVALLSAL-RGDFLRSESKE -QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EREGRRETVAAISEAIYH-- ->[subseq from] Putative beta-lactamase n=2 Tax=Collinsella aerofaciens TaxID=74426 RepID=A4EC45_COLAA ----LQQDIEALVEPYDGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVT -AGELSLDEQITVTQQDIVGGSGNIQSRGAGVYGIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTQTVLARLMMDTEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Beta-lactamase n=1 Tax=Bacillus cereus VD048 TaxID=1053226 RepID=J8HHN6_BACCE ------------------------------------------------------------- -----KLDKVNTYIKDDLVEYSPITEKHVDTGMTLGEIAEAAIRYSDNTAGNILFKKLDGP -KGFEKELGQNGNKVTLADCFELDMKEAIQGDICDTSTAKTLAFNLKAFTVRDALQTDKRK -IPTDWMRGNATGDELIHAGVPKDWEVDDKSGAGSYGTPNDIAIV---------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea polychroma TaxID=46176 RepID=A0A438MNR8_9ACTN --------FETLFRMAGVTGWLYAADIDSGREV-GHGADEQLPTASMFKVPLLVEFCRQAD -AGLLDPTSRVTVTAGDRVPPTGISAMLDDVTISLRDLAYLMIAVSDNSSADVLLGRV-GI -DAINAMLARHGLMSTRVSQSAKEINEALDPARANRSTPREMARLFGLIWRDEAASVASCA -WMRAVLNMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea pusilla TaxID=46177 RepID=A0A1H8B8I9_9ACTN -------DFAALFHAAGVTGWIHARDLDTGREV-GLGPDEPLPTASMFKVPLLVEFCRQAD -AGLLDPASRVTVTAADRVSPTGVSGMLDDVTISLRDLAYLMITVSDNTAADVLLARV-GM -DAVNRMLDGFGLHVTRVVMSGRVMLGVLDPARTNRSTPREMATLLGLVWHDRAAGAASCA -WMRGVLGMQVW-PHRLASGFPDDVAVSGKTGTLPT-LRGEAGVVEYPDGGRYAVAVFTRS -YSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3G6HHI5_ALCFA --eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVLLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI00124526F3 ------------------------------------------------------------- ----------------------------------------------DNMAIVRLRNAEAGE -PRLMALARELGVPRSALKASLDDVFDAYYAGDRNHATLPAFATLLERLAAGELLSPESTQ -RMLDHMRAISTGDRRLSAGLPPGTDFAQKTGTQLR-RACNVGVIDAAAGAGATVVLACAE -DFDELAQAEQAFQAFGRAL---- ->[subseq from] Serine hydrolase n=1 Tax=Streptosporangium sp. 'caverna' TaxID=2202249 RepID=A0A2Z3ULG8_9ACTN -------AIEGLFRTAGVTGSLHVVDIDTGAEV-AHDADESVVVASVFKVALLVELFRQAD -RGVLDPAERVTVMADRHTAPTGVSVMADDVTMSLRDLAYLMIAVSDNTAADAVIDRV-GL -PAVNTMLAAFGLDRTWIEHDCRELFSALDPARTNRSTPRDMTRLLGMIWRDEAASPGSCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Salegentibacter TaxID=143222 RepID=A0A1I2NEB2_9FLAO --eELQHTIDSIFKITQGDFAIAFKDLSEEKNSiFINHHEDFHAASTMKTPVMIEVFKQAS -AGKFALQDSLIVKNQSILDGSSYSYEQIDQKRSIEDLVTDMIIYSSNLATNIIIELV-DA -KNVNKTMRNLDAKNINVLRGVEDMK-AYEAGLSNSTTAYDLMLIFEDLATGNAVNPEADE -KMLNILRQQKH-TDLIPHLLPENLKIANKTGWIT-GVHHDSALIELPDGRKYVLVLLSKN -ME-DMDTGTKMLNQVSKMIYEH- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI00132FDC18 ---TIQGTIDDAFGDMQGETSVYVSPTDSTGEV--VSNSKAQRAASNIKLFILITAYQQVN -EGKLNLNDKYTLKDSDKVNGTGIRNMSSGTEISIQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNTQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] Uncharacterized protein n=2 Tax=Sphingobacteriia TaxID=117747 RepID=A0A258WSR7_9SPHI --qKTEKDLQTIMATSPSLSGLMAVDLSSGESI-SINENVVFTQASAIKIPILMEVYKQAH -EKKFALTDIKPLLPSNTVAGSGILNVMVDPVLSIRNLCVLMIGLSDNSATNTLIELV-GM -KNVTNTMQSLGFSNTRLQRKMIDQPAS-LRNEENISTPAEAVRIMKLLYEGKFIDKSTSD -EILSILMNNPVANSKIADGISANVKIAFKPGGMG-GVSTEWAIVYLSNR-PYAITIMENY -KT--SATPSNIISALSKRVFDYf ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Bacteroides pyogenes TaxID=310300 RepID=UPI0011E40F8B ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTLAQSDNNASNLMFKDMVNV -AQTDSLIATIPRSSFQIAYTEEEMSADHNRAYSNYTSPLGVAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGYNGAHNDVAYICLPNNVCYTLAIFVKD -FKGDESQASQYVAHISEVVYS-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus murinus DSM 20452 = NBRC 14221 TaxID=1423772 RepID=A0A0R2BR46_9LACO -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNNEEQ---------------- ->[subseq from] Serine hydrolase n=1 Tax=Ornithinibacillus sp. TaxID=1898027 RepID=A0A3C1I1S4_9BACI --kSLTETIQKVVDDAGGLWGISLLDLDTNDSW-ELNEHELFYAASVIKVPIMIAAFAASH -NGEMELSKKVVLKREDIVGGSGVLQYMTPGTVAIYDLITLMIIQSDNTATNLLVDLI-GT -EKIQQEMENIGLEKSCYYHKMMIGS--VDRKEFNQITAAEMTMMLKKLVTGKIVSIHACE -QMIDIMKKQQI-RHTLPSKIEKEFEIAHKTGNVL-GIRHDIGIFYVGQRK-MIASILSKG ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Nocardia amamiensis TaxID=404578 RepID=UPI00082DE872 ------ERIRAVFADAGCTGWLHARRCDSAAEI-SIGGRERVVVASVYKLPLFVAFCRSVD -AGRIDPTARLTVTPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL -GAVEELLDQLGLTQTRIVGGTADLHRAYDPSYTSATTPEEMTRFLRALWSGTVLSAEQTE -FVRSVMRYQVW-PHRIAAAFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPVVDAAIAETARIAVT-- ->[subseq from] hypothetical protein n=1 Tax=Lactobacillus TaxID=1578 RepID=UPI000826B1BC -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNNEEQ---------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC62_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKT---------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. Ag1 TaxID=1643451 RepID=A0A0M2XYJ7_9SPHI --kKLESQIKQLIQGFQGDVGIYVHHLKKNKEV-NIQGDSIFPTASIVKIPILVGIFDKIE -KGELQLDQQLLYRSSQRYGGSGLMQFFKDSTVDLKTLVALMLSYSDNVTSIWNQKLAGGG -IAINQLMSSLQLPHTRVNSQTEGRKPDWEKYGWGQTTPKEMADLVTLIRQGKVVSSKSSD -QMYRFMGNMFY-DERGLSQIPSTIKTASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NTGKTNEAEILTRKLSKLLWDYy ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001378CFF1 ------------------------------------------------------------- --------------------------------LTAPELARATQLTSDNAAANLLIRKLGGP -EAVTALWRASGDEVSRLDRLEPDMNLLPPGDLRDSTSPRAMAQHVARLFTSEMLVPEDRE -RLREWMVETGTGLARLRAATPPHWQAGDKTGSAIPNKTHDVAVFWPPGRAPVIVAAYYES -DAHHRAQDEAVLAQVGRIAV--- ->[subseq from] Uncharacterized protein n=2 Tax=Sutterella sp. AM11-39 TaxID=2292075 RepID=A0A415CH74_9BURK ---ASQAAIVALEKKYDAAIGVSLRDAKGKVLL-EWRSRERFPLTSTVKALECARVYELGL ------ENHYAPIKTTPIVPHSPVYGKDPDTQVTLKEACRAALSQSDNRAANFIFVHTGGP -KALTEWLRQKGDNTTRSDRLEPDLNLSGKNEYRDTTTPSNASLNWQRF--DSTLPQAARE -QWLSDLASNQMAGNLFRSRLPENWTLYDRSGAGSDETRANHAILVTDKGVRYYAAVHLKA -PATPMEKRDAILQQAIEVVYAH- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MKI1_9BACT ----LHEELEALALKNKARIGVALHDLQTGFRF-SFRGDRWFHAASTIKVAVLLAVFRAAD -EGQFRLDDSLHVRNRFFSAADGSLYAAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV -EYARTVLRDAQVDGVELRRGVEDH-GAHEQGINNEATADGLLRLLS-VIRGDFLTPESKR -EVIRILLEQRF-NSMIPAGLPPHATVAHKTGETST-ACHDIGIIYLPEREPYIAAILTEF -DP-EREGRRETVAAISQAIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A3D0L3K0_ALCFA --eRLQERLEPLLNQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLTVMADG -FT--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Lawsonibacter asaccharolyticus TaxID=2108523 RepID=A0A2P2F742_9FIRM -----QNEIYRILSGLAGTVGLYVEDCQSGEIF-TINPEHVFPSASVIKVPMLALLMRDAQ -QGLVDLDAPRTIDPRNRVGGTGILCELGTDYPSLRDLAKLMIVLSDNIATNEIMDVI-GM -ERFNSFCREMGYQNITLMRKMMDFE-AIQQGKNNYMCAGETGRLLSAISRGEFVNPEISQ -TIFDIMASQQC-RNKLPALLPAVVLVANKTGDLV-GIQHDVGIFELPDGRRYLIAMFTGD -LEND-SAGIAAISQVSLAVYQ-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5QAR4_ECOLX ---DVQQNLAELERQSGGRLGVALINTADNSQI-LYRADERLAMCSTSKVMAVAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEKHVDGTMSLAELSAAALQYSDNVAMNKLISHVGGP -ASVTAFARQLGDETFRLDR----------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Cyanobacteria bacterium UBA11440 TaxID=2055784 RepID=A0A359BLT6_9CYAN ---ELENSLKALNNKYNIKPAVFVWSMDNSNYV-DIGGDVVYPSASIIKLPVLIQMYKSIE -AEQFGLKDNMTLTEYYRSEGSGNMQYSQAGRYSITDLATTMIQDSDNTATNMLISKVGSM -NDVNAAIKSWGIEHTHLQTWLPDITGN------NYTTAKDIAQMLYNIGKNKFLNINSQS -DIINIMSKVKN-TMLIKAGLPENVSFIHKTGDIGT-MLGDAGIVYLPSGQRYIVVILALR -PHNN-INGRLYIQEASKIIYNY- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GN37_9BACT ---TLREALEKLARESKARVAVALLDLESGFRF-SLAGDRWFHAASTIKLAVLLAIFRAAD -ERRLRLDDSLHVRNHFVSAGSPFRYQAIGRTAKISALTEGMIVASSNLATNLLLDCL-GV -EYARNVLRDAQVSGVELRRGVEDQ-AAHEKGIDNEATADGLLTLLSAL-RGDFLKKESKE -QAIHVLLAQRF-NSMIPAGLPAHATVAHKTGEIST-ACHDVGIVYLPEREPYIAVILTEF -DA-EQNGRRETVAAISEVIYR-- ->[subseq from] Serine hydrolase n=2 Tax=Lactobacillus sp. CBA3606 TaxID=2099789 RepID=A0A2R3JV09_9LACO ---TIRQAINTSLSGLKGTTSVAVAATASSAKV--VQNDQSQRAASLIKLFILITAYEQAD -SDQLNLDETYTLTANDKVGGTGTLQGLPTGSLSYREILKRMMDESDNTAANIMIDKVGGI -STVNAEIERLDLSKTQLERKMMDTD-ALADGKDNYTSVTDVATVLTKMYAGKLISPTADQ -AMLTIMRQNAN-HAKLPHDLPSAAIIYNKTGEYDYGVQNDAAIIKNKHGA-FVVVVLSQG -GDEAA--QV-------------- ->[subseq from] Uncharacterized protein n=2 Tax=Rubricoccus marinus TaxID=716817 RepID=A0A259U2R5_9BACT --dALRQRIEAIAARYEATVAVAVRD--GETRL-DIAADRPFHAASTMKVPVMIEAFRQVE -AGRLAWDDSIDVVNRSIVDGSPFSYERLGTRMPLADLTRRAITTSSNLATNLMMEVL-TA -DSVQATTRALGGEGVLVLRGVEDLKA-FDAGLSNLATARGLAALMLAIQDGRAVSPEASG -DMVEILLAQEF-GEMIPAGLPAGVRAAHKTGWITH-VHHDAAIVYPPEAAPYVLVILTEG -ID-DHGRAAALGAEIAAAVH--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8V8B3_9BACT ----VEDALRARIGDFQGTVSLYAKNLDTGSTT-GIRESDAVRTASTIKLPIMLAVFDAVA -RGQAKWTEPLTVTADEKVSGSGVIGSEISDYLPLRDVLHLMIVLSDNTATNMILERF-TA -DAVNAYLDKIGIKTTRSLRKVRDGNQENQKYGLGVTTPRDMVTILEKLERGEIVSPDASR -EMIAVLKRCQD-NSGIRRPMG-DVPVANKTGALD-ALRSDVGIVYSKGG-RIAMAITVDG -MPTPDNTGTILIADLARILVD-- ->[subseq from] CfxA family class A beta-lactamase n=1 Tax=Bacteroidales bacterium 52_46 TaxID=1897040 RepID=A0A1Q6EF40_9BACT ---QLRDSLSHIAGEYPGEIGIALL-TSAGDTV-VVADEDKYPLMSVFKLHQAISLCRLFD -EQGASLDTVLEIPRRKLNPWSPMLKDYTADPISVRDMLRYTLTQSDNNASNYLFETVEPV -AAADSFISTIPRAGFRIVATEAEMFDNHALCYENHSSPLGAALLIDRLFTDSIIDTASRD -FICTTLGQCTTGTDRIVAPLADGVTVAHKTGSGFRNAHNDVAFVTLPDGTSYSLAVFVKD -FNGSEQEAARAIARISSTIYT-- ->[subseq from] serine hydrolase n=1 Tax=Atopobium sp. Marseille-P4126 TaxID=2094145 RepID=UPI000D558AD7 ---ALKSELEQVVAPYGNAVSISVADIRTGATC-DINANKQVISASMIKLAVMAAYLQAVD -AGTINPQQALPLARMKIVGGTGKIQSERARTYTYDALCRYMIMYSDNTATNALIDAL-GV -NTVNTRARELGCTQTTLNRKLMQLNTG----VENYTSAADVSRLLCAFYTQTAASAGQCT -KAMDFLLQQTD-GDGIPQGLS-GVQFAHKTGTLG-GIRHDGGIVMA--RSPYTIVVMCEL -PEG---KANALMTQVARKTQQYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_9 TaxID=1916320 RepID=A0A292RGZ2_9BACT ---ELENSLKALNNKYNIKPAVFVWSMDNSNYV-DIGGDVVYPSASIIKLPVLIQMYKSIE -AEQFGLKDNMTLTEYYRSEGSGNMQYSQAGRYSITDLATTMIQDSDNTATNMLISKVGSM -NDVNAAIKSWGIEHTHLQTWLPDITGN------NYTTAKDIAQMLYNIGKNKFLNINSQS -DIINIMSKVKN-TMLIKAGLPENVSFIHKTGDIGT-MLGDAGIVYLPSGQRYIVVILALR -PHNN-INGRLYIQEASKIIYNY- ->[subseq from] serine hydrolase n=1 Tax=Algoriphagus antarcticus TaxID=238540 RepID=UPI000A370282 --kQLESSIRELAMSFQGDIGIYIKNLKTGASV-EINSDSIFPTASIVKIPILLAVFDKIE -KGELHYREPLIYRDSIKYGGSGIMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQALAGGG -AQINEVMEQLGYNNTRVNSRTPGRESIWEKYGWGQTTPKEMADILERLNNKELISPAASE -QMYRLLSNTFY-TDYALAGIPAGINVASKQGMVD-ASRSEVFLVNSPQGD-YVCAIFTKN -NKDHDNEVWVLTRKISNLIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HJM8_9BACT ----LHEELEALALKNKARIGVALHDLETGFRF-SFRGDRWFHAASTIKVAVLLALFRAAD -EGRFRLDDSLHVRNRFFSAADGSLYAAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV -EYARTVLRDAQVDGVELRRGVEDH-GAHEQGINNEATADGLLRLLSAI-RGDFLTPESKR -EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIIYLPEREPYIAAILTEF -DP-EREGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus antarcticus TaxID=238540 RepID=A0A3E0DZB6_9BACT --kQLESSIRELAMSFQGDIGIYIKNLKTGASV-EINSDSIFPTASIVKIPILLAVFDKIE -KGELHYREPLIYRDSIKYGGSGIMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQALAGGG -AQINEVMEQLGYNNTRVNSRTPGRESIWEKYGWGQTTPKEMADILERLNNKELISPAASE -QMYRLLSNTFY-TDYALAGIPAGINVASKQGMVD-ASRSEVFLVNSPQGD-YVCAIFTKN -NKDHDNEVWVLTRKISNLIWNHf ->[subseq from] Beta-lactamase n=1 Tax=Pseudomonas fulva TaxID=47880 RepID=A0A0D0KS46_9PSED ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANVLDLQTDQLESDLDEAYSRYYDSGLNSATLVAYGQLLGKLATGDLLNGDSSA -LLYDIMGLGGYDAYRLEAGLNEDLPFIQKTGTQQH-RACHMGIANPQDERALVIVACAED -LDE-NDEAGTLFEQVGEAI---- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JHV2_9BACT ---TLSDRIAALTRGFNGTVAIYARNLDTGQDF-AVGADTRVRTASTIKLPILCALEDLVA -KGRIAWTLPVPVRAEDRVSGSGVLAESPGATLPLRDVATLMIIVSDNTATNLVIDRI-TA -DAVNDYLDTLGLTATRSMRKVRGDGTQQPENQRGSSTPREMVRLLELLEQGQVVSPTASK -NVLDLLKRQQF-KTGIGRRVGGDVQVASKSGALD-ALRSDVGIAHTKGG-RIAMAITVDD -MPSPDNAGEELIWEISKVLM--- ->[subseq from] serine hydrolase n=1 Tax=Nocardia carnea TaxID=37328 RepID=UPI0002D36700 ----VAERIHAVFADAGCTGRLHARRCDGGTEV-SIGGTERVVTASVYKLPLLLAYCRAVD -AGRIDPLQRLTLTPAECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL -ADVHDLLTSLGLTRTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGEVVSAQQTD -FARAVMRRQVW-PHRIAAGFPRAVSVAGKTGTIGI-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Microbispora catharanthi TaxID=1712871 RepID=A0A5N6C231_9ACTN ---------ERVFRNAGVTGWLHAVDIDDGREV-GLRADEPVVLASVFKVPLLLELHRQAE -RGLLDLTERVGVPAADRTSGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNTLLDGLGLTATRVVQDCRDMLTALDPAVGNRSTPREMTGLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LSQNQPRADAAIGAAARMAIDQ- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea solani TaxID=1144553 RepID=A0A1H6BZH7_9ACTN --------FEHLFRLAGVTGRIYAADLDTGHDV-GLGADDPVPTASIFKVPLLVAFCRQAD -AGLLDPTERVTVTADDRVPPTGISMMLDDVTISLRDLAYLMMAVSDNSSADKLLARV-GF -DAVDAMLKSFGLAETRVTQSAREMHEALDPAIANRSTPRETARLFGLIWRDEAASSESCA -WMRAVLNAQVW-PHRLASGFPDDVAVSGKTGTIPT-LRCEAGVVEYPDGARYAVSVFTHS -FGLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Microbispora sp. KK1-11 TaxID=2053005 RepID=A0A544ZAK8_9ACTN ---------ERVFRSAGVTGWLHAVDIDRGREV-GLGADQPVVLASVFKVPLLLELHRQAE -RGLLDLTERVGVPAADRTAGTGLAAMLDDATLSLRDLAYLMMAVSDNTAADVLLARV-GR -EAVNALLDGLGLTATRVVQNCRDMLAALDPALGNRSTPREMTRLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -FSQNQPRADAAVGAAARMAIDQ- ->[subseq from] Beta-lactamase n=1 Tax=Bacteroides vulgatus TaxID=821 RepID=A0A397WIZ3_BACVU ----LTDSISRIVSACPGEIGVAII-INNTDTV-KVNDKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVKIDRNRLDSWSPMMKDYSELVLTVRDLLRYTIAQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHDRAYFNYTSPLGAAMLMNRLFTESIVSGEKQS -FIKNTLKECVTGTDRIVAPLKERVSIAHKTGSGCNGAHNDVAYICLPNNVCYTLAIFVKD -FKGNESQASQYVAHISEVVYS-- ->[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RPS6_9BACT ----LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDSLHVRNRFISAGSSFHYQTIGRTAKISALAEGMIASSSNLATNLLLDFV-GV -EYARNVLRDAHVEGVELRRGVED-HAAHERDINNEATANGLLTLLSA-VRGNFLSSDSKE -QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EHDGRRETVAAISEAIFR-- ->[subseq from] Serine hydrolase n=2 Tax=Alcaligenes TaxID=507 RepID=A0A4P8JI62_ALCFA --eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPESLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. 7894-2 TaxID=2021695 RepID=A0A268ILY0_9BACI --hTLKAEILTLASSCEGRVAVCIH---TGDGViEKDADAVFSSASLIKVPILLAGLSQAE -KGMLQLEEELEVTVSARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI -EKINQLFKNLGFNHTSLNRKMMDFE-ALKNGIDNTTTARDMLYGIKALAEQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVTVAGKTGELP-GIEHDCAIFTHKGKA-VCAAVLVDR -LQN-QAAGKEVLSAIGSRI---- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536A8Y0_9CHLR ---------RERLSTLPGEAAAYVCDPSGRELF-SERADEPFPAASVIKLPLVMAIFADAA -RGRVDLDERVAVGE--RVDGSGVLRHMRDVELSLRDLAMLAVIVSDNTATNRLIDRI-GV -ERVNERLREWGCPNTRLARRMYDFAAA-ERGAENLMTARETASLLVRLIRGECEDRATSE -AVMALLAECQD-RTMLRRYLPNAADVANKTGTLDE-SRNDAAIVRGE--PTVVVAAFTRK -LRDTE------------------ ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6A8QBA6_9BACT --qHLKDRISERLEGVKGDFAVAFKNLEDTTESvYINEREMFHAASTMKTPVMIELFKQAE -AGKFSLDDSIIIKNESIVDSSLYRYSRIGEKRTIRQLINDMITVSSNLSTNILIEKV-GA -RNVSRTMRSYGADSIKVLRGVEDIK-AYQQGLSNRTTARDESIIYEKLGRGEAVSEEASE -QMIEILTNQHF-NEMIPAQLPGEVVVAHKTGWIT-GINHDAGLIILPDEQKYVLVLLSKN -AP-DREKVLAAFADISHYVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Prevotella sp. ne3005 TaxID=1761887 RepID=A0A1H8D967_9BACT --------------------------MQNGSIV-GINEDKPFAMHSVMKFPQALCVADYLN -RKGLDLDDTIVVDKADLMQWSPMLKRFECKTFSFAELLELSLGQSDNNASELLFKHCGKP -KAVEKYMRKLGFRDIHVRMTEEQMHKRPTKAIENSSTPAEMVRLFEWFYHHKD-DNRYLT -FIWKAMADCSTGLKRIPAAITADARIVHKTGTGFLQDMNDAGIILMLDGSHAIIAVFTTN -SS-----SEAVIANITRQLLD-- ->[subseq from] N-acetylmuramoyl-L-alanine amidase n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P8AUH4_9BACT -----------------LTLSVLIQAPDGTELF-AHQADRQVPSASVIKTPILVTLLQMAA -KGDIDLSETYTLTEADIVGGTGDLQHEGPGLLSWLDYARLMIKTSDNVATNVIIAKV-GM -DAVNALTTSLEMDQTVLARYMMDTK-AIEEGRQNYTSPRDMNRLLLALYHGRILDAPERA -LFWDMLKDCDD-DTMLRAGVPPQYTVANKTGILSY-VRGDSGVLFGQQ--DFIITAFAED -FN-DVSRAEQAIADVVR------ ->[subseq from] CubicO group peptidase, beta-lactamase class C family n=1 Tax=Olivibacter domesticus TaxID=407022 RepID=A0A1H7W921_9SPHI ------KVLAAFDKQPTGTFAVAFRAIDDGETF-LLNEHQLFHAASTMKTSVLVEVFKQTE -KGKFSISDSIKVYNKSIYDGSSYTYSKIGLKVTIEDLLNRMITESSNLATNMMIDLV-GA -KNVMKTMRSIGANEMKVLRGVEDGK-AFEHNMNNMITANDLMILFDQIAQGKMISKKASD -AMVAILSKQHF-RGIIPAGLPADVKVANKTGSINK-ISHDSGIVYLPDGRKYVLILLSKG -IEE--EVAKRTLSSVSTYVYRY- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus animalis TaxID=1605 RepID=A0A062XBL9_9LACO ---------------------VYVAPMNEDVSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLAYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNN-EERS-------------- ->[subseq from] Beta-lactamase n=1 Tax=Tannerella sp. oral taxon BU063 isolate Cell 1/3 TaxID=1411022 RepID=W2CQD2_9BACT -------------------------IVNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGDNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZV22_9BACT ----LHEELEALALKNKARIGVALHDLETGFRF-SFRGDRWFHAASTIKVAVLLALFRAAD -EGRFRLDDSLHVRNRFFSAADGSLYTAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV -EYARTVLRDAQVDGVELRRGVEDH-GAHEEGINNEATADGLLRLLSAI-RGDFLTPESKR -EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIIYLPEREPYIAAILTEF -DP-EREGRRETVAAISEAIYR-- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645CDR0_9ZZZZ ------QKIFEILGSLEGKVSLYAEDLDSGETL-VICPEEIHVACSLIKIPILALLLKDGE -EGKVDIEAKIQIPEERRVGGTGMICHLSEGLLSWKDIMKLMIAVSDNTATNAIIDLL-GM -ERINAFFGDIGLFSTELQRKMMDLDA-VKAGRNNYTTAADMGKVLKMAASGTLVSRRASE -TVLEIMSRQFY-TNKLPAMLPAVVAVANKTGDLPK-TQHDMGYFVLPGGRKYIIAMLTSN -LS-SDQEGISCIGKVSKAVYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus koreensis TaxID=284581 RepID=A0A0M0LIE9_9BACI --qDLQNTIENIVNGISGRMGVYVQL--GNEHI-NVNGDLSMPSASLIKIPILLELFHQVE -QGLIHLREINEIKDFKRVGGAGVLQSLTNDVLTWYDLAVLMITVSDNMATNALIHRL-NM -NAVNDYCHAF-TEATVLQREMMDYE-AIKKGKDNWTSARDMVKLLTLIENEQFLSRESRQ -EIYSILTKQQF-QDKLPARMDDTVTIANKTGELE-GVEHDVAIIDGYGQ-RIYVAVLTHQ -LVNS-YKGRSAISAIGYELYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=A0A2U2BJD5_ALCFA --eRLQERLEPLLTQESARISMAVYATDGTSLF-EWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI00052D29A6 --eRLQERLEPLLTQESARISMAVYATDGTSLF-EWQAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLDTVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLKHTDLQRHMMDMKAR-EAGKDNWTTVQDACSTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAILPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Algoriphagus resistens TaxID=1750590 RepID=UPI000716AAC3 ---QLNSTIISQLDSIKGDVAVAYINLSDPSDSlMINAEQEFHAASTMKVPVMIELFKQES -QGKFNLNDSILLKNESIVDSSLYSYSKIGTRQSLRDLMYSMITVSSNLATNVLIELV-DA -KNVTATMRELGADKIEVLRGVEDTK-AYELGMSNTTNAKDLLIVMKAIAENKAGTNKACE -EMISTLTDQKF-NTIIPFYLPETVSVAHKTGSIS-GVHHDAGIVYLPDGRSYVLVILSKN -LE-DYDTATEQLARISKTVYEY- ->[subseq from] serine hydrolase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI0003FE1061 ---ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE -RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL -AAVNRVAAELVDARLRIT------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=unclassified Pseudoxanthomonas TaxID=2645906 RepID=UPI0003FE1061 ------------------------------------------------------------- ----------------------------------------------------------AGP -ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG -WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG -IG--TAAGVHALQRIAAAI---- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6HTM0_9BACT ---TLNEEVERLSAESNARIAVAAHDFESGLGF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLHLDDSLHVRNRFISAGSSFHHQLVGRTVKISTLAEGMIATSSNLATNLLLDFV-GV -EYARKVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVSLLSAV-RGDFLRNESKE -QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EGNGRREIVAAISVAIYR-- ->[subseq from] Beta-lactamase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=A0A174A444_9ACTN ----LQQDIEALAEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVA -AGGLSLDEQVTVAQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DAVNETCAALGLTQTVLARLMMDAEAQ-ARGRENYTSARDAATVLQHLAAGTIATPELYE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E3J1T3_9BACT ------EELQSAIEGVQGTVGFAAKHLETGQQL-SHNADSIFFTAGTLKVPLLTELYRQVD -EGYINLSERIELSDDLRVPRSGIFKELATGLPTVRDAAMLMIIISDNTATDALMEMV-GR -ESLHDTRQTWGLLQTRIPMSVRQLLYAYDEAKSDVSSPADMSRLLELLQSGDILSPESTA -DALDILKRQQL-RTVIPHTLPIGTSAAHKTGFYL-GVRADAGIVSGPNG-PYTIAIMAKN -ITASDRVKDLSLSPISAAIYRAf ->[subseq from] serine hydrolase n=1 Tax=Gordonibacter sp. Marseille-P4307 TaxID=2161815 RepID=UPI000F5251EE ----IEALVSRSEAQFGMEVGVAYLDLSDGARF-EINGYRSQVSASMIKLLILSEFARQVD -AGTIGLDDRYVLQRSDIVGGTGSLQSRGAGAITYAELAEKMIAESDNVATNVLIDRL-GM -DAINGESQRLGLSETRLNRKMMDVAA-VSSGVENYMSAVDAMHILKLIYQNDLASPALNK -LALDALNGQTD-NRGIRDGLPEGMTFAHKTGTLS-AVQNDGGIAGG--DRPFILVVFCQS -KAGSAQAAFSLMENIANII---- ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Thermokryptus mobilis TaxID=1643428 RepID=A0A0S4MU31_9BACT ---EVVSKIQKVAKKYGGRLGLSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLVSLDDSLKYGGAGVLQYFYNGALKLIDVAVLMIILSDNTATNLVLDCFANL -EAVNSRMKSLGLENTKILNKLMSFKTKKNTPEAGYTTPNDMLKLLEMLANGKIINPSVSA -EIINIMKNNQD-YEMMKRYLPEKVAVANKTGSIDR-MKADIGIVYSQCT-TYAVAIFCDQ -LSAVDNKGHLAIAEISKIIFDYf ->[subseq from] Beta-lactamase n=1 Tax=Plautia stali symbiont TaxID=891974 RepID=U3TR40_9ENTR ------------------------------------------------------------- ------------------------------------------------------------- ---------EIGDNKYRLDRNEPSLNTAIPGDNRDTTTPDAMAESLNKLVLGSVLAETQRA -KLTEWMKGNTTGLNSIRAGLPSDWAVGDKTGSGDYGTTNDIAVIWPKDHAPIVLTTYFTQ -RVKDASARKDVLASAAKLVAE-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_2_20CM_2_66_4 TaxID=1803462 RepID=A0A1Q7AFE3_9BACT --qRLQASIERTTKSINATWGIYVKSLETSEEI-ALDADRQMETMSTIKIPLMVEAFEQMK -AGKFRLTDKYTFAQADSQPGTGIIQRLDPGALTGKDLITLMVIVSDNTATEVLYRMVGGI -DAVNRRMDAMGLKSTRAMSLPTAWFAREGKHPFGLSTPREMGRLLEMMERGTLVDKASSD -LMLQIMRGQLY-RTRIPRYVT-GYRVPHKTGDFLPFVGDDVGMLEADGR-TIVVSIFTGN -HFGSGEALENAIGLVAKEVADYy ->[subseq from] serine hydrolase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=UPI0009E72439 ----LQQDIEALAEPYGGSTSVYAVALDLDGEV-AVAPDARRVAASIIKLPILACALETVA -AGGLSLDEQVTVAQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DAVNETCAALGLTQTVLARLMMDAEAQ-ARGRENYTSARDAATVLQHLAAGTIATPELYE -RARGYLLAQED-ARGIVEGVPGGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] serine hydrolase n=2 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI000FD65743 --nQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ -EGRLDLHQPYAVPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM -GTVNKLSDGLGCGATVLGRKMLDFQAK-RNEKDNFTSARDMIIFLKEIVGGSTLKQEAKD -AALQLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD -LV-DNLPAQQVISTIGKAVFDY- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3QZJ4_9BURK --------ARTQAEAHGLQLGVHVRDLDSGVSA-NWGGKRSWYLASMVKVPVAIAVLKAVD -DGVVTLDTQLTVRASDYVDGAGSTNASVGTPLSVRFLIEQMIIHSDNTASDMLIDLV-GL -DAINALVRQHVPEGMQRITTLAEVRRDYYAGQLNSGQLDAYGDLLAQLVQGSLLSRASTA -HLLGVMERVVTGPNRLRAGLPAHVRLAHKTGTQR-ARICDGGVARVSQQARRVLIVACVS -GAGPRVQAERALAHTAAAVC--- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium grantii DSM 8605 TaxID=1121316 RepID=A0A1M5UDF2_9CLOT -----RKKILKIINEYGINTAIYYKNLENNKKF-TLNEKEKLPSASLIKLFIMYHAFKKVS -EESLSLEIQIPVNRNDTVEYSIIEA-LSIDKYSLEDLITLMIIQSDNTATNILINYL-GM -SNINDTINELSMQKTSLNRKMMDFYAR-ENGIDNWTSAEDVGELLYKIYKDEFRNSELNK -KIFAIMKRQIF-MTMIPRYLNESYEIFNKTGDLPN-INNDAAIIFHSQGN-SILVILTKD -CK-DKYKAQEFVGKVAKIILE-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9NDE0_9BACT ---ALQDKIAQIRSQFPGEMSIYMKNLDSGDEI-TVDSDKVFETFSVIKLTIAAELMHQVE -GGKFSLSDRIPLTAGDERLPSGVLYALDPGLPTVNDLLTLMIILSDNEATDILADKV-GR -ENITTYMHSLGLANTSIRYTDLDWDRYDAGIYFGHSTTREIGQLLEMMVGGKLVSKSSSD -RLLGIMEKQQV-NDRFPRYLK-DIRIAHKTGDGQPFIANDAGILWVNG-EPIVLVVFTGH -HRGTTTSLHDAIARIAA------ ->[subseq from] serine hydrolase n=1 Tax=Nocardia niwae TaxID=626084 RepID=UPI0007A3F8F3 ----TEDRIRAVFADAGCSGWLHARRCDGSATEvSVGGDERVVLASVYKLPLFVAFCRQVD -AGRIDPAARLTVIPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAA-GL -GAVESLLDDLGLDRTRVVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGTVLSAEQTD -FVRTVMRLQVW-PHRVAAGFPRSVATAGKTGTIGV-IRNEVAVVEFPGEHPVAVAVFTRA -ARADLPAVDAAIAETARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Prevotellaceae bacterium MN60 TaxID=1945887 RepID=A0A239R6N4_9BACT --------------------------MQNGSIV-GINEDKPFAMHSVMKFPQALYVADYLS -RKGVELDDTIVVDKADLMQWSPMLKFFEGVKFSYGELLELSLEQSDNNASELLFKYCGKP -HAVENYMRELGFHDIHVRMTEEEMHKNPAKAIENSSTPTEMVRLFEWFHHHKD-DNQYLT -FIWKAMADCSTGLKRIPAAIPADARIVHKTGTGFLQDMNDAGIILMLDGSHAIIAVFTTN -SS-----SEAVIANITRQLLD-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea zeae TaxID=1642303 RepID=A0A5S4F2Z1_9ACTN --------FDALFRMAGVTGWLYAADIDADRQI-GHGADEPLPIASMFKVPLMVELCRQAD -AGLLDLAARVTVTRADRVPPTGISAMLDDVTISLRDLAYLMIAVSDNSAADVLLGVV-GF -DAVNSMLAGFGLGGTHVSQSCKESNDVLDPARSNRSTPREMARLFGLIWRDEAASAESCA -WMRAVLNMQVW-PHRLASGFPDDVAVSGKTGSFPT-LRNESGVVEYPDGRRYAVAVFTRS -LSTAQPRADAVIGTAARMAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=A0A1I3I420_9PSED --eALHQRLGELENASPGKLGVYLLRPHDGSEL-NYQAERTWYLASATKAAIAIAVLQEVD -DGKLQLDQPITLEEGDRVDGSGLVWEDAGARYSVGELLREMLQESDNTAADMLIRVA-GE -ARVNERIAAAADNGF--------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas argentinensis TaxID=289370 RepID=A0A1I3I420_9PSED ------------------------------------------------------------- -----------------------------------------------------------GP -QRVEAVANALNLQTAQLESDLDEAYRRYYASGLNSATLVAYGRLMGKLAKGELLSDASTR -LLYDIMGLDSYEAYRLEAGLSEQLPFVQKTGTQLH-RACHMGIANPQGDDALVILACAEA -LDED-VEAGKLFEQVGEAI---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Alphaproteobacteria bacterium HGW-Alphaproteobacteria-13 TaxID=2013659 RepID=A0A2N3DY97_9PROT ------------------------------------------------------------D -QGRIPLDQPVRIGPEDLTLHQPIAVRVRSEGMPVRELIETAITHSDNSANDSLLRTVGGP -EAVRRFLARKDMGAIRFGPGERLLQAAYLADPVDGASPSAIASALTRLARGSLLSPESTE -YLLGVMTRTKSGPQRLKAGLPPGWRFLHKTGTGQTAGYNDIGIATAPDGTRYAIVVLLGN -TTARIPERMALMQAVSGAVAE-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=I0AXW9_9BACT ---ETLVKVKDAEHXLGARXGYIELDLNXGKILeSFRPEERFPMMSTFKVLLCGAVLSRID -VGQXQLGRRIHYSQNDLVEYSPFTDKHLTDGMTVRELCIAAITMXDNTAAKLLLTTIGGP -KELIAFLXNMGDHXTRXDRWEXELNEXIPND----------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=UPI001232C48D ------------------------------------------------------------- -------------------------------------------------AANLLLATVGGP -AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASQRGARGIVALLGPNNKAERIVVIYLRD -TPA-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5S9N5_9BACT ----LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDLV-GV -EYARNVLRDAHVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGNFLSSDSKE -QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EHDGRRETVAAISEAIFR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Flavisolibacter ginsengisoli DSM 18119 TaxID=1121884 RepID=A0A1M5CEN7_9BACT --kKLQRQVHELLQGFNGQVGVYVKNLKNGKVV-AINEDSIFPTASMVKVPILTGVMDKVN -KGELDLHQNLTYRDSLLYAGVDILGSFKDTEIELGKVVMLMLVMSDNTASLWLQSLAGTG -KRINAIMDSLGFQSTRVNSRTPGREANRAQYGWGQTTPREMATLMEKIVKGEIINKERSA -QMLRLLGRNYW-DEYAISQIPSDVFVASKGGAVDE-SRSEVLFVNGH-GARYVFCINTKN -IKAKSNEAWELTRKLSKLLWDHf ->[subseq from] hypothetical protein n=1 Tax=Acidisphaera sp. L21 TaxID=1641851 RepID=UPI00131C1357 ----------------GVTIGVAALA-PAGEPF-AYHGSRRFVAASTVKIAIMVELFRRID -AGRITLEQRHILREDEKAGGSGVVSNHTGIEMTIRDLVYLMMSVSDNSSTNILIDAL-GI -EAINATMCDIGMQHSTLGRKMRGRHLV-ASEAENWAVPEDYVTVIKSILDGHAASSESCA -QMVALLEKQQN-DRRIARHLPNRPRWGTKTGSLP-GVVNDVGFIMTGRG-PLILAVFCEG -LT-DGPTGEQIVGDIAKAALD-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Nocardia TaxID=2637762 RepID=UPI00135745D1 ----AQDRIRAVFADAGCSGWLHARRCDGSATEiSVGGDERVVLASVYKLPLFVAFCRLVD -TGRIDPAARLTVAPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL -GAVEGLLDDLGLTRTRIVGGTADLHRAYDPAYTSATTPEEMTRLLRALWSGAVLSDEQTE -FVRTVMRHQVW-PHRVTAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAIFTRA -ARADLPVVDAAIAETARIAVT-- ->[subseq from] DUF3471 domain-containing protein n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q5S9F0_9BACT -------VLDAFAEHPAGKFAVAFKDLKTGTSL-LINERDQFHAASTMKTPVLIETFKQAA -AGKFNISDPILIRNESIVDSSLYSYTKLNTKLPLYEVLHRMITRSSNLATNLVIDLI-GA -ENANATMRSLGAHDIQVLRGVED-NKAFAKGLNNSTTAYDLMIIMDALATGKAVNTKASE -EMIKILMDQKH-LDKIARKLPPGVKVASKSGSIT-AVSHDSGIIYLPDGRKYVLVLLSSG -VQ-SYDDVNNTLANVSKMFYD-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus infantis TaxID=324767 RepID=A0A5D4R4K8_9BACI --nQLEQRLADILRQCPGNASLAVEY--GEMAI-YMNSGRTYPAASLIKIPIMMEAFFQAE -AGALDLNEQVRIGGIEKSGGAGIIQSSVKASLSILDCITLMIIVSDNTAANLLIKLL-GK -KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIENFTTAADMVKCLRAIKDGELFSEKNRS -RMLDIMEAQQF-REKLPAIACKDLKIANKTGELP-GIEHDCAIFTS-GRDDLYAAVLIDS -LS-SPEEGKHAIRQIGS------ ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=UPI000D52B55D --eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLESVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACLTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6JHC9_9BACT ----LHEELEALALKNKARIGVALHDLETGFRF-SFRGDRWFHAASTIKVAVLLALFRAAD -EGRFRLDDSLHVPNRFFSAADGSLYAAIGRTAKISSLAHAMICGSSNLATNLLLEFV-GV -EYARTVLRDAQVDGVELRRGVEDH-GAHEQGINNEATADGLLRLLSAI-RGDFLTPESKR -EVIRILLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIIYLPEREPYIAAILTEF -DP-EREGRRETVAAISQAIYR-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7RVQ6_9BACT ---TLEETIRARLDSLQAQSSFYAKQLASGHEV-SIRADVPMNTASVIKIPVMILAFRDAD -AGRLDLDQRYVIRPEDQRRGSGLLQTFAPGIPTLRDIVTQMIITSDNTATDIMIAKV-GR -DRVNRMLDSLGYRQTRLNATTGDLFRADSSKWLGKTTAREIGRLLEQLQRGDLASKASTQ -EMLRILRQQFY-ASRLPQRIRFRAGIAHKTGDWPPLLGNDVGIIYAPSG-PIVAAVFTNM -NRGDFTDLEATEGRIGEDLLNA- ->[subseq from] Serine hydrolase n=1 Tax=Ammoniphilus sp. CFH 90114 TaxID=2493665 RepID=A0A4Q1SPQ9_9BACL ------SVLLNIIEDAGGTWGIVAEDLNHQLRL-EYGEQVSFTAESIIKIPIMAAVFAEVE -KQQLSLSDLVLLKREDLVGGSGVLQHLSPGILPVYDLLMLMIIQSDNTATNLLIDLV-GT -KQVQQTMADLEMLDSQFHRKLMVYPAE--IVEKNRITAADVSLLLKKLATGSFLSHKACQ -QMINILKKQQI-RNGLPAYLSAHWQLANKTGWDT-GAQHDVGIFYIGQR-TMTITVLSKD -VD--AIVALDAIARIGREIYHY- ->[subseq from] serine hydrolase n=1 Tax=Paenibacillus elgii TaxID=189691 RepID=UPI0013D106A4 --nQLEATIRQAASSVEGKAGIAV-DTAEGQIH--IHADEPFPSASLIKIPILLEAYRQAQ -EGRLDLHQPYAIPSGERVGGTGVIHQLSGALLSLQDLMALMIIVSDNTATNMIIDLI-GM -GTVNKLSDGLGCGATVLGRKMLDFQAK-RNGKDNFTSARDMIIFLKEIVGGSTLKQEAKD -AALRLLRNQQF-NAKLPARIIDKPVLAHKTGELP-GTEHDAGILQVNGK-TAYIAVLTTD -LV-DNLPAQQVISTIGKAVFDY- ->[subseq from] Beta-lactamase class A n=2 Tax=Imperialibacter sp. EC-SDR9 TaxID=2038371 RepID=A0A5E8A4D2_9BACT --nELKQSIAAAFEANTGDYAIAFKDLSNPDNQlYINEKETFHAASTMKTPVMIELFRQAR -AGKFSLSDSILVVNESIVDSSAYTYSFIGQKLTIYDLTYEMITVSSNLATNILIELV-GA -PNVMTTMKSFGANDIQVLRGVEDQK-AYELGMNNTTTAKDLAIVMEMIATDKAGTPEDCA -AMIKILKDQRF-NDIIPTYLPDSVSVAHKTGSITK-LHHDSGIVYLPDGRKYVLVLLSKN -LN-TIEEGTEVLARVSEKIYSY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SM23_52 TaxID=1703359 RepID=A0A0S8H3F2_9BACT ---SLEERVRARLDSLDARTSLYAKHLPSGREI-AVRADQPMNALSVIKIPIMLLAYRDAA -AGRLDLDERYRIRPEDMRRGSGLLQTFAPGLPTYRGLVTQMIITSDNSATDIMIERL-GL -ERVNEMLAELGYEETRLRTTTGQLFRALEGDSTQWTTAREIARLLEGIHNARLASPESSQ -EMIRILRRQFY-SSRLPQRIRFQAAVAHKTGDWPPYAGNDVGILYYEGG-PTVVAVFTNQ -NRGDFFELEATIGRIAEDLIS-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus versmoldensis DSM 14857 = KCTC 3814 TaxID=1423815 RepID=A0A0R1SLG1_9LACO --------------ESDGQTSAYFYDLNSDQHA-QYGDDSTQRAASNIKLFIMAAAYQKVK -DGELDLSDHYTLKDSDKVGGTGVVQQMETGSISYHDLIKDMITQSDNTAANIMVDTIGGL -DVVNDEISDLGLSDTTMERKLMDTEK-LEAGHDNMTTAHDLGIFMKKLYNHQVVSKTYDE -DMLGILKDTSN-HSKLPSQVASDITVYNKTGEYNYGVQNDVAIFQKGDKA-FVISVMSED -GTESDQ--KE------------- ->[subseq from] serine hydrolase n=1 Tax=Nocardia beijingensis TaxID=95162 RepID=UPI000832923D ----AEDRIRAVFADAGCSGWLHARRCDGSATEiSVGGDERVVLASVYKLPLFVAFCRHVD -AGRIDPATRLTVVPSDCTPPTGIAVLRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL -GAVESLLDDLGLERTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWNGTVLSAEQTG -FVRAVMRLQVW-PHRVAAGFPRNVSIAGKTGTIGV-IRNEVAVVEFPGEHPVAVAVFTRA -ARADLPAVDAAIAETARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JM23_9BACT -----TQLLESHLAGFPARTGLYVKHLGTGEEA-AVRGDESFSSASVIKLAIMIRAFQLVD -AKTLDLNARVTIGRADLRDGSGVLQYHDLGLPTYRDLITEMVITSDNTATDLMVQKIGGV -EALNKWLMASGFTHTQMV------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q6UIV7_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSQKDTSTPAAFG------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E4P453_9BACT ----LEKKIIETLNSQKGDFSVAFKNLSNKXTI-LINENEEFHAASTMKTPVMIEVFKKAQ -KGIISLDDSIKIKNESIADGSTFKYDKIGSYLSLRELVFDMITISSNFATNLVIDYI-GS -DNINNTMRDLGAKNINVLRGVEDIKA-FNQGMNNTTTALDLLKIYENLAVGNVINSEISK -EMVEILKKQKY-DDIIPKYLPKSIEVAHKDGWIN-GVRHDSGIVFLEDNTTYLLVLLSKN -LE-DEIKGADLLAKVSLEIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0399 TaxID=2032565 RepID=A0A2A3LNF6_9GAMM --dALARRLAAVDAAYPGEIGVYVHHVGRDESW-GLRANESWYLASGVKVPIAIAVMREIE -QGWLTLDTEVTLLETDFVDGAGRTNAHRAGDLTIAWLLDQMIVYSDNTASDVLIRTV-GL -GQVNAVAAELIASQGVHITTLADVRRSYYATHVNSATLGDYGRMLVALQQGLALDAEHTA -YLLGVMSRVKTGQRRIRAGLQPTADFAHKTGTQYR-RLCDSGIVTMPAGPPVVVAACVRG -PT--GATGERALRSIGEAVT--- ->[subseq from] Serine hydrolase n=1 Tax=Caenimonas sp. HX-9-20 TaxID=2596921 RepID=A0A562ZFB8_9BURK -------------DANASAIAVATYDFMHHTAW-SLNPERWFHAASTIKVPVLVAVYDAIE -QGRFEPHSRVHVRNRSVVDGRPFREVHAAIGLTVHELAEHMIVTSSNLATNLLLDLV-GI -EAARASLARLRLGGIDLLRGVEDE-LAWEAGLNNRVTAAGLCAALRMIDEGQAISKDACK -AMLDILHQQRF-RTGIPAGLPEDARVAHKTGEIST-VAHDAGIVYLDGRDAYVVVILTEW -AP-EVNGRQETIARISRAVYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_41_12 TaxID=1974745 RepID=A0A2H0M3M2_9BACT ----LNDDLKSKIASFKGKVALVVEDLNTGWVI-SFNENILMPSASLVKIPIMLSCYYAQQ -EGRINLKGSLRLKSFQKVSGSKVLGDSPVGSFVIEELFDPMITLSDNSAANVLIGLM-GF -NDWNMYFKKMGLKNTNIVRNMMDFRSR-RRGRENYTTAVDMAYILEKLYRRQFLSQEISE -KCLILLSQQKI-NDRIPRKLPQDILAVHKTGLERH-ICHDVGIVYTRKGN-FLICVLVKH -ENKFAQPAKKLISEIALSIYNYy ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. CAG:1060_57_27 TaxID=1896975 RepID=A0A1Q6FRW7_9BACE ---SLYAAIDSLSSGLDARVGVAAV-FDGGDTL-VYDSRAEYPLMSVMKFHQALAVCDSLR -RAGIPLSRGLDVCPGQLHEWSPMRDGHPSGGFSFAQLLEYTLVQSDNNACDILFDYLGEP -AAVDAYLRSFGVGDCSIECTEDMMHKDLSLCYRNASTPLSAVLLLEKFYLLRG-SDPYYR -FLWDTMTACGTGTMRIPRFISKAAAIAHKTGTGDRDSINDIGVVVLPDGRHFSLAVFVSD -AAVPDALCEELIAEIARLAYEH- ->[subseq from] serine hydrolase n=1 Tax=Nocardia exalbida TaxID=290231 RepID=UPI00031C9C03 ----TEDRIRAVFADAGCSGRLHARRCDSATEI-SVGGDERVVLASVYKLPLFVAFCRLVD -AGRIDPAARLTVAPSECTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL -GAVEGLLDDLGLTRTRIVGGTADLHRAYDPSYTSATTPEEMTRLLRALWSGAVLSDEQTE -FVRTVMRHQVW-PHRVTAGFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAIFTRA -ARADLPVVDAAIAETARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5SHR4_9BACT ----LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDSLHVRNRFISAADGCSYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV -EYARHVLRDAHVEGVELRRGVED-HAAHERDINNEATANGLLTLLSA-VRGNFLSSDSKE -QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EHDGRRETVAAISEAIFR-- ->[subseq from] Serine hydrolase n=2 Tax=Collinsella sp. AM36-4AA TaxID=2292317 RepID=A0A396A7R4_9ACTN ----LQQDIEALVEPYGGSTSVYAVALDSQTEV-AVAPDARRVAASIIKLSILACALETVT -AGELSLDEQITVTQRDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVFSGVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LE--REQALALERDISSAIYA-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia testacea TaxID=248551 RepID=UPI00030FB899 -----AERIRAIFADAGCTGRLHARRCDSDEEV-CIGGTERVVTASVYKLPLLLAYCRAVD -AGRLDPLARLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEV-GL -TAVHELLESLGLDRTRLVGGTADIHRAYDPAYTSATTPAEMTRLLAALWRGEVVSTEQTD -FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPAVDAAIAEGARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Calorimonas adulescens TaxID=2606906 RepID=A0A5D8QCJ5_9THEO ------EDIEKYIQDSDIDASIYIKSMRGDFEF-KHKETRVMPSASLIKLPMMACIYDLAY -DDRLDMEQKLKPRREQIVAGSGVIKDHADIEYSIRDLTYLMITVSDNTAANILIDYL-GM -DRINDEIEKLGMKDTVLRRYMMDSAA-RAAGIENLTTVLDMGLFFEKLYDGDVVNYLASR -EMTDILKAQRF--NVMDYYLPKRYKVAHKTGSLE-GYEHDCGIIFSQEDD-VIVCVMTSG -FKND-YEGIDYIKGLAKIIV--- ->[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrionales bacterium RIFOXYD1_FULL_55_31 TaxID=1797404 RepID=A0A1F3XV12_9PROT ------------------------------------------------------------- ----------------------------------------------------------GTR -ARLRALMRKLGLRRAQLGASIDEAFERYYARGYNSGSLEGFGTVLEKLVRRELLSPAHTE -LLLGYMEQIQTGDHRIKAGIPKTVRFAQKTGTQVR-RLCNVGVMLPSGSSEAVLIAACVE -KYSDFKEAEKALQKVGRAIS--- ->[subseq from] Possible beta-lactamase class A n=1 Tax=Lactobacillus otakiensis DSM 19908 = JCM 15040 TaxID=1423780 RepID=S4NQK6_9LACO ---QIKTALKACVTNASGKTAGYVKQIGDHQPV-EFSGNRRQRSASVIKIFVMIEAFRQIK -AGTLRLSDSISIPQSDKVGGTGVLANQNTQHLTCGQLLNLMIKNSDNTATNVLIDKLGGL -GPINQSIKKLGCSNTSLQRKMLDYS-ALQSGRDNYTSASDVGKTLNMIYTHRLLGSGWDT -KMLNLLQGNAN-QTKIPAQIKNSATIYNKTGEFDYGVQNDAAIIQKGNRA-FIAVILSEN -GTQSS------------------ ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A641AEW7_9CHLR --qQLENTLKTKIDEFDGVAGVSLKSFSSGKHI-SINGDEIFPTASTIKIHILAKLFYLEE -KGEIDLSERIRFTQDKYGGGSGVIHFLENDPFTVLDVAILMMLASDNTATNMCIDIA-GI -ESINDLIQDMGLPETKLRRKMMDPE-AIDRGDENVSTPNELVMMMNQLHNGKPTSKVSS- -QVLRIMSKPKS--AYLNKAIGSEVTVANKPGGMDK-VRGDTGIVYLPNN-PYTVSIMSKF -SMVDSLSQEGFIIDLARTIHR-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Luteitalea pratensis TaxID=1855912 RepID=A0A143PYZ7_9BACT ----FSRRLDEVASSVDGSVAYLVVDVTSGQRF-ARRADEPFPTASAIKIGILYELFVQVD -AGREVLDDPKPLPEASRAGGSGIINRLRSPVLSLRDHALLMILLSDNTSTNVLIDTL-GM -DAINAHMQALGTSGYRLRRRMMDSAAAARG-DENVASASDLVTVMDAIRTGRGLRPESQA -EAIRILREY--GPTSVRAGIPADVPVATKPGGLD-GVRSEVSWVDVKGR-PYLLCVMTSF -LA-DDQAGEKAITEISRTSYQYf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium GWC2_71_9 TaxID=1798310 RepID=A0A1G0L758_9BACT ----------RIAAQPGATVGLYYRSLVAPDSM-AIGADIRFHAASTMKVAVMIQAFRDID -SARLRLDERLPVVNASIADGSTYEYALVGRTAPVRQLVELMITISSNLATNVLIERV-GA -ARVQATLRELGTDSMVVLRGVEDGA-AYRAGLNNTTTARDLAILLEAIADGRAASAASCG -RMLQILLHQRI-NDAIPRGLPRRTPVAHKTGGLT-GQYHDAAIVYTRRRPQYVLVVLTRG -IA-QHEAATQLIADLAGII---- ->[subseq from] serine hydrolase n=1 Tax=Gemmatimonas phototrophica TaxID=1379270 RepID=UPI0006A6B5DA ----LTRLLEADLARYPATAGVYVKNLRTGEEA-MVNADQSFSSASVIKIPIMIRAFQLAD -QHTLMLDERVEITRAELRDGTGVFQFLDMGLPTVKDLITQMIITSDNTATDLMTTRVGGV -ERLNAWLAASGYSRTRMVNRGHE------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3G2HZA0_9BURK --eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLESVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACSALLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. (strain 21) TaxID=743722 RepID=UPI0012F957CF -----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE -RGKLALSDSVEVYNESIYDGSSYAYSLIGKKATLADLLLRMITQSSNLATNIVIDLV-GA -KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE -QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG -VD--EKLAQQYLAEISGVFYHY- ->[subseq from] serine hydrolase n=1 Tax=Nocardia grenadensis TaxID=931537 RepID=UPI0007A42EC5 -----AERIRAVFADAGCTGRLHARRCDSDAEV-SIGGTERVVTASVYKLPLLLAYCRAVD -AGRLDPLARLTLVPGECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL -AAVHELVESLGLDLTRLVGGTADIQRAYDPAYTSATTPEEMTRLLAALWRGEVLSGEQTD -FARAVMRRQVW-PHRIAAGFPRGVSVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6LLQ5_9BACT ----LHEELETLALRNKARIGVALHDLETGFRF-SLCGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLDDSLHVRNRFFSAGSLFRYATIGRTAKISALAHAMICGSSNLATNLLLDFL-GV -EYARTVLREAQVDGVELRRGVEDH-SAHEQGINNEATADGLLKLLSAI-RGDFLTPESKR -EVIRVLLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIVYLPEREPYIAAILTEF -DP-DTEGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. (strain 21) TaxID=743722 RepID=F4C695_SPHS2 -----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE -RGKLALSDSVEVYNESIYDGSSYAYSLIGKKATLADLLLRMITQSSNLATNIVIDLV-GA -KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE -QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG -VD--EKLAQQYLAEISGVFYHY- ->[subseq from] hypothetical protein n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=UPI0012E8CB88 ----LQQDIEALVEPYGGSTSVYAVALDFNGEV-AVAPDVRRVAASIIKLPILACALETAT -AGELSLDEQIMVTQQDIVGGSGNIQSRGAGVYSIDELLHAMIAQSDNVAANLVIGRL-GM -DTVNETCAALGLTKTALARLMMDVEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPALCE -RARGYLLAQED-ACGIVEGVPGGVLVAHKTGSLAD-AQHDVAIVYAE--RPYVLAILTQD -LEREQ------------------ ->[subseq from] class A beta-lactamase n=1 Tax=Asaia platycodi TaxID=610243 RepID=UPI000470A12E ------------------------------------------------------------- --------------------------------LSLAALCAGAVTMSDNVCANMLLRHIGGP -AALTRFWRDSGDDVTRLDAFEPELNRPSADPQANTTSPVAMARTLHRLIHGTLLHPHSAA -LLRGWMISCTTGTHRLRAGLPPHWIAGDKTGNNGKDISADIAFATLEAQRSIIMTAYTSG -GTPDEARFRKVFHDIGALA---- ->[subseq from] serine hydrolase n=1 Tax=Nocardia pneumoniae TaxID=228601 RepID=UPI000A06F8A5 ---SAEERIRAVFADAGCTGWLHARRCDSAAEI-SIGGRERVVVASVYKLPLFVAFCRCVD -AGRIDPTARLTVTPSDCTPPTGIAVMRDPVTMSLRDLATSMMTVSDNAAADVLLGAT-GL -GAVEELLDQLGLTQTRIVGGTADLHRAYDPSYTSATTPEEMTRFLRALWSGSVLSAEQTE -FVRGVMRCQVW-PHRIAAAFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARSDLPVVDAAIAETARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Globicatella sulfidifaciens DSM 15739 TaxID=1121925 RepID=A0A1T4LH38_9LACT ----------------------QALDHKTSSQP-LILNNQPMRSASIIKLFVLAALFEQVE -KGEMDLTEQYVLKAEDKVSGTGDIQNMQDGTLTLLTLAEKMIIISDNTATNILINLIGGI -EKVQNIIVELGYSDVQLKRLMVDLES-LKAGEDNYVTVEDVGRILADIYQEKLVSKSASQ -KMLAVLKQQTD-RQMLARNLPSDVTYYGKTGNFDYGVQNDAAIIETPNGA-FILVFLSQE -GQ--KEQQLKAMNKLGKVVSELf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC60_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVS ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIEFNYYSPKSKKDTSTPAAFG------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase AST-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645ARD5_9ZZZZ -----AEAVQKETEAFRGTTGVVVSSLADGRRL-SHNADRVFSSASLIKLGVLYTLFSKHA -SGEIDLDEVYGFSSAECADGGLLHRVRSGARLRLDDLALLMISVSDNTAANLLIDRL-GM -DAVNGGFRELGLSGTVLGRKMLDFEAK-KAGKDNFTTAGDMAVLLETLHSGQNFPASARS -RMMEMLSLQKL-NSKLPGLIPVEQFLAHKTGELP-GNEHDAGVFFFRGRKPVVVSVLTEG -LK-DRSEGVEFCARIGRILYDAf ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus oceanisediminis 2691 TaxID=1196031 RepID=A0A160M662_9BACI ----IKAEILDLASCCEGRVAVYIHT--EDGVI-ETNADDVISSASLIKVPILLAGLSQAE -NALLDLDEEAEVKDAARVGGAGVLQAMSKGLMKVIDLMTLMVIVSDNTATNLIIERL-GI -EKINQFIKSLGFNCTELNRKMMDFE-ALKNGMDNTTTARDMVYGMKALAENSLLSGKFTE -KALDILEKQQYKNKLANTMDTEKVKVASKTGELP-GIEHDCAIFTHKGN-TVYAAVLVDQ -LQ-SQAAGREVLSAIGSR----- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7W665_9BACT -----------IKDEHALRLGISFYDAETTVQW-SYNADAWFHAASTMKLAVLLGVFREVD -RGELALDAPVHVRNRSIVNQEAFMYGHLGKTLSVKELAYWMITKSSNLATNLLVDVI-GI -PTIQLALDELEIHGIKVLRGVEDQ-RAFAAGLNNEVTAHGLLKMLRLIAEGTAYSQEACD -EMLDILLDQQY-RSGIPAGLPKAARVAHKTGNIST-VHHDAGIVYLEGRKPYVLVILTQF -PAE--QGRGTAVAEVSRDIFN-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus pentosaceus TaxID=1255 RepID=UPI0007625832 ---TIQGTIDDAFGDMKGETSVYVSPTDSTEEV--VSNSKAQRAASNIKLFILITAYQQVN -EVKLNLNDKYTLKDSDKVDGTGIRNMSSGSEISMQDLLEDMMEDSDNTAANIVIRQLGGM -DKVNAQIKKIGAKDTKLERMLMDTD-ALKDGKDNYTSVADLGMVLKKIYNHQMVSTKYDN -AMLDILKKNNN-HTKLPHDLPEEATVYNKTGEFDYGVENDAAIFGNNKG-SFVIVVMSQD -GSRDEQ----------------- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Sphingobacterium thalpophilum TaxID=259 RepID=A0A4U9VA44_9SPHI --kRLESQIKQLIQGFQGDVGIYVHHLKKHKEV-NIQADSIFPTASVVKIPILVGVFDKIE -KGQLQLDQEFIYRESQKYGGSGLMQFFKDSTVDLKTLVGLMLSYSDNVTSIWNQKLAGGG -VAINSLMEGLQLTHTRVNSQTEGRKADWEKYGWGQTTPKEMADLVTLIREGRVISAKASD -RMYRFLGNMFY-DERGLSQIPATVKAASKTGSLDD-VRNEVILVNAPKGD-YVFSIFTKN -NKGKNNEAEELTRKLSKLLWEYy ->[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Trichococcus flocculiformis TaxID=82803 RepID=A0A181ZN37_9LACT ------SIIENAYSPIMGTFSAYVSRIGNENEV--VVNEQPQRAASTIKLFIMLTTYSKAN -ANELDLDSIHRLYEDEKVGGTGIIQDMPGGSLTIRELIRLMIVESDNTAANIMIDELGGF -ESINQMISKMGCYNTALNRKMMDTNA-LESGIDNYTSAKDLGVIMKKLYMNTLISEEYDN -EMLSILSHNTD-HSKLPYHLPYGATVFNKTGTYSYGVENDVAIIANENGA-FVVSVMTQD -GSA-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5XTV1_9BACT ---TLRERVERLTAESKARTAVSVHDLESGFRF-SLRGNRWFHAASTIKVAVLLALFRAVD -NGRVRLDDSLHVRNRFFSAGSPFQYQAIGRTAKISMLAEGMISASSNLATNLLLGFL-GV -EYARNVLREAQVDGVELRRGVEDH-AAHEKGINNEATADGLITLLSAL-RGDFLRSESKE -QAIGILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIIYLPEREPYIAVILTEF -DS-EKEGRRETVAAISQAIYQ-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes faecalis TaxID=511 RepID=UPI000F0BC7E0 --eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLESVYPLPEGERTPGTGILSQLPGVPLSLRELALLMIILSDNVATNVLIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EAGKDNWTTAQDACLTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Nonomuraea gerenzanensis TaxID=93944 RepID=A0A1M4E0Z5_9ACTN -------AFEQLFRAAGVTGWLYAADIDTGHDL-GHGADEPMPTASMFKVPLLVALCRQAD -AGLLDLTERVTVTAADRVSPTGISSMLDDVTISLRDLAYLMIALSDNTAADKLLGRV-GL -DVIGAMLEGFGLARTRVVQGSGEMLGVLDPARTNRSTAREMARLFGMIWRDEAASPASCA -WMRGVLNMQVW-PHRMASGFPDDVAVSGKTGTMPT-LRCETGVVEYPDGGRYAVSVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] SLH domain-containing protein n=1 Tax=Paenibacillus rhizosphaerae TaxID=297318 RepID=A0A1R1EPP7_9BACL ------------AEKDGIRMSVGIRDLSGHETL-LLGSREPYMPASTIKLAVVSALMKQVD -RGELSLADQVRVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM -DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQQAARAIYS-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535E6J3_9CHLR ----LARQVRCLEDEFSGVLGLWAHDLRRRRTY-ELRAGEPFPAASTIKLFILHELLRQAE -AGRLSLADEVVMGRTDVVPGSGVLKDLSPGVLSLRDAATLMVTVSDNVASNLLIGRL-GV -GAINQGARACGCLQTRLGGKLFRTR--APG---STTTPRDLARLMLGIARRRAVSPTASS -LMLDILRREQS-DLIVGRLLPEEWTVASKHGSLP-GVRNDVAYVRGRTG-RYVIALMSRD -CADPDNEAVLCLARVARAVHDH- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7QEU1_9BACT ---TLRQRLDARIARAPARVGLYYRSLARADSI-LIGANLRFHAASTMKLPVMIQIFRDAD -AGLLGLDDSLTVHTASLVEGAFVVYALVGRNRAVRDLLERMITRSSNLATNILIERV-GA -ARAQASARSLGAWSMQVLRGVEDGA-AYRAGLNNTTTARDLGVLLEAIATRRAASGAACD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAAVVFPPDGGGYVLVVLTGG -IKED-SVAHNLVADLSRLVY--- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A3B8ZGQ3_9PLAN ----LGSKIAPLVQSHAGQVSVAVKHLTSGAEY-FLDADRPMPTASLIKFPVMVEAYRQRA -AGLVDFSAPIQVTEADKVPGSGIITDHFADLLSLRDAVQLMIAFSDNTATNLVIDKI-GI -ASTGQSMEQLGFPNTKIYARVFRHDTSIDPERSGSTTAREMILLYEQLEKGQLVSPEACQ -EMKKHLLACDD-NTKLKKLLPLGTKVAHKTGAVS-AVRTDSGLIYTPSG-PIAVCVLTSE -NKDQSWQD--------------- ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI001158FEF1 ------------------------------------------------------------- -----------------------------------------------------LLTTIRGP -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQI----------- ->[subseq from] Uncharacterized protein n=1 Tax=Euryarchaeota archaeon RBG_13_57_23 TaxID=1797977 RepID=A0A1F9YY88_9EURY ---KLRSEIHKIAKDVKGQFGLYLKHLESGKEM-AIDADKIFPLGSVFKIPVMMEVYRQAS -EGLVSLDEKLKLEPRYYCIGSGILQYLSPGLLTVRDLITLMIIATDNTASEMLWKRV-GI -QRVNMLMRELGLHKTSI------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter sp. 24 TaxID=2183986 RepID=A0A4R6FVP7_9FLAO --eELQEQITNIFKRNQGEFAIAFKNLSKKNDSiLIQEKKDFHAASTMKTPVMIEVFKQAS -EGKFSLQDSLTIKNESILDGSSYSYALIGNKRSIENLTVDMIINSSNLATNILIELV-DA -KNVNKTMKNLGATNINVLRGVEDIK-AYEAGLSNTTTAYDLMLIFEALAKGIAVSPVCDQ -KMLDILYRQKH-TDVIPALLPENLKIANKTGWIT-GVHHDSALVELPDGKQYVLVLLSKN -ME-NMQAGTKMLSEISKMIYDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptosporangium canum TaxID=324952 RepID=A0A1I3F842_9ACTN ------------FRAAGVTGFLHAVDLDTGAEV-AHGADEPVVMASVFKLALLVEFFRQAD -AGRLDVTERITVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLVGRV-GL -SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Alphaproteobacteria bacterium 33-17 TaxID=1895704 RepID=A0A1Q3P861_9PROT ---------KHLEDNFKIRIGFHAMDLDSGRSI-GYRNNESFIMASTVKVPVSIYLMNQVD -EGNIDLAKMIYIDKSDLVPGSGKIGYFLTHDISNANLLELMMAISDNTATDLIIRQL-GM -NNIAKFFNSY--PDISLKHNIMQLFDDFYYNKADRTTPKAMALILKDFMDGKFTSIKSRD -FLLKVMSHTENKDRLKKEVLHSSDFIHHKTGTFDYYSIADVGIVKLKSCKKIIISLYLDS -VDLNAKDLEQVLSIAARIITDYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0011E92FA8 ----LEEKILDAIDKCKGRISVAI-DLPS-HSI-QINSDTPYSAASLIKVPILLEGYRQSE -HGKIDLDETVMVPNEYRVGGAGVLSTLSERILTVEDLLTLMIIVSDNTATNLIIDRL-GT -EAINNLCNSLALKHTKLIRKMMDFQA-MKQGYDNFTSASDIITCLRSLDQGTLFNQQSRD -KMLYMLHQQQF-NTKLPARMDEKIYIANKTGELP-GVEHACAIVRSEEKT-AYIVVLIDE -LDEN-ESARDTIAEIGKLLHDY- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus sp. FI11369 TaxID=2306423 RepID=A0A3R8KF67_9LACO ---AVQRDVDKALTGMGGTTSVAVLPVTGSGQV--VNNNQSQRAASLIKLFILVTVYQRAT -DQELSLDDSYSLQSSDKVGGTGTLQNLPNGSLTYREITKRMIDESDNTAANIMIAAVGGM -GNVNAEIKSLRLTDTKLERHLMDTA-ALKSGKDNYTSVKDVAKVLQRLYNHRLVSERADT -QMLSVLKNNAN-HAKLPKNLPSDAVVYNKTGEYNYGVQNDAAIIKNSRGA-FIAVVLSQD -GK--EASQVTAMNQLGAALYQ-- ->[subseq from] serine hydrolase n=1 Tax=Gaetbulibacter sp. S0825 TaxID=2720084 RepID=UPI00143092D5 ----LKTDIEQQIQTIEGDIAVGFLDLSNEENTiLINVDEKFHAASTMKVPVMIELYKQQN -QGLISLSDSIVLVNESIVDGSSYKYSKIGTKQTLYDLMVPMVTVSSNLATNVLIEIV-DA -KKTTQTMRDLGANKIEVLRGVEDIK-AYEQGLSNSTTARDLMVIMKAIANGTAGTKEDCE -VMLSILKDQQW-NDMIPKYLPDNVEVAHKTGSIT-GVHHDAAIVYPPNGKDYVLVLLSKN -LK-DFDEGTNKLAKISERIFS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=Q2FC76_STAEP ----HTKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASMKYSDNTANKKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes aquatilis TaxID=323284 RepID=A0A3R9B7Z2_9BURK --eRLQERLEPLLTQESARISMAVYATDGTSLF-DWHAQRVMPSASLIKTPMLLCLLEQVA -QGKLSLESVYPLPEGDRTPGTGILSQLPGVPLSLRELALLMIILSDNVATNALIDLL-GM -DNINAWSAQAGLQHTDLQRHMMDMKAR-EVGKDNWTTAQDACLTLLYLLHSPALPENLRQ -QGLDMLADQRE-RGHFAAMLPSIAQLAHKTGSLP-GLRHDAGILTMGER-SVVLAVMADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. SYP-A9097 TaxID=2663237 RepID=UPI00129AD02D -----------------------------TAEV-TVDGHARVVTASVYKLPLFVAFCRSVD -AGRIDPTARLTVIPSDCTPPTGIAALHDPVTMSWRDLATSMMTVSDNAAADVLLGEI-GL -APVEDLLRDLGLTETRIVGGTADQHEAYDPTYASATTPEEMTRFLAALWTGTLISPAQTD -FVRAVMRNQVW-PHRIAAGFPRGVSVAGKTGTVGI-IRNEVAVVEFPGEYPVTVAVFTRA -ARADLPAVDAAIAEAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A6B1FY08_9GAMM ---ELAARVTARLDGLPARTSLFARHLPSGREI-AIRADEPMNALSVIKIPVMVLAYRDAE -AGRLDLDERYRIRPEDLRRGSGLLQTFAPELPTWRDLITQMIITSDNTATDIMIARL-GQ -ERVNEMLSEFGYEQTRLRATTGELFRRFEGDSEEWITAREIAGLLEQIHNADVASRASSD -EMIRILERQFY-STRLPRYIRFRASVAHKTGDWPPYAGNDVGILYYEGG-PTVIAVFTNQ -NTGDFIELESTLGRIAEDIVNSw ->[subseq from] serine hydrolase n=1 Tax=Aliifodinibius saliphilus TaxID=1920650 RepID=UPI00110842C5 ---TLKSSIKKQLQEVKGDFAIAFKNLSDTTQVlYINEREKFHAASTMKTPVMIELFKQAE -IGRFSLGDSILVKNESIVDSSRYKYDLIGSKRTIRQLITDMITMSSNLATNILIEKV-GA -HNVTQTMRSYGADSIKVLRGVEDIK-AYERGLSNRTTAIDEAIIYEQLGRGKAVNKEASN -EMIEILKKQHF-NKMIPAQLPNEVEVAHKTGWIT-GVNHDVGLITLSNGEKYVLVLLSKN -AP-NREEVLTTFANISANIYE-- ->[subseq from] serine hydrolase n=1 Tax=Robertkochia solimangrovi TaxID=2213046 RepID=UPI00117C6649 ----LEATIQSQIDSIAGDIAVAFLNLSDPSDTlFIAADEKFHAASTMKVPVMIELFKQQE -AGTLNLNDSILLINESIVDGSPYSYDKINSRVALNDLMYSMITVSSNLATNVLIELV-DA -KNVTATMRDLGAQKIEVLRGVEDQK-AYDMGLSNSTTARDLQIIMESIASGKAGTKEDCD -SMIAILKDQQF-NEIIPKELPENVSVAHKTGSIT-GIHHDAGIIYLPDGGSYVLVLLSKN -LE-DFDKGTEQLAGISRSFYAH- ->[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013EF33DB ---EVTERIRAVFADAGCTGWLHARRCGSAAEI-SVGGRDRVVTASVYKLVLFVAFCRRVD -AGLIDPRAQLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG -FVRAVMRKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Fictibacillus arsenicus TaxID=255247 RepID=A0A1B1Z532_9BACI -----ENDLLHLISSGKGVYGVSIYHFETEEEF-SHNQNEEFYAASIIKLPIMSAVFAQVA -EGKRSLSDKIQIRSEDIVSGDGILKNLSPGMWTIHDLVVLMIIESDNTATNLLIDLI-GV -ENIQLYMTIWGFKTTQFRHKLQ-IKPSRKHNESNLITAKEINNFLRNIAMGNIVSMSVCS -KMVDIMKQQKM-NGLLPSLLPENWEMAHKTGYVP-GVEHNAGLFYLPGQT-FAITALGKN -VP-NRDEPKRIMGELGLLLYE-- ->[subseq from] serine hydrolase n=1 Tax=Leptolyngbya sp. BC1307 TaxID=2029589 RepID=UPI000EFB487B ---ALKAQFEDLPNLYGLTAKLFYVDVDTGDYV-DLAGREAIAAASTIKLPILLAFFEEVD -AGRINPNQTMTIQPDQLADGSGEMQVAPGTQFTALEVATQMIVSSDNTATNMMIDLLGGS -AALNSKFAAYGLEKTRLNGPLPDLDGT------NTTSARDLAQTLLLVTQDETLTLRSRD -RVLNILQRTYN-KSLLAAGLEKEALTYNKTGDIAS-VLGDAALVDLSNGKRYIVAVLVER -PTND-GRAVELIRRISGRIYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Prevotellaceae bacterium HUN156 TaxID=1520830 RepID=A0A1K1PA97_9BACT -------------------------KGGTER---RINATSRFPMYSVMKFPQALYVADFLT -RNDIDLNTEVLVRKEEMLQWSPMLSTFEDQRFTYSELLALSLQQSDNNACDILFERCGGP -RAVDKYLRDLGFKDIRIQKTEKQMHDTPALSEQNWCTPQSMVTLLEWFIAHHN-DNEPLR -YIWKLMAECQTGGDRLPAAVPNSAKVVHKTGTGYPSGICDVGIIILDNGQQLPIAIFIIN -PSSQ------------------- ->[subseq from] hypothetical protein n=2 Tax=Paenibacillus cellulositrophicus TaxID=562959 RepID=UPI0012673142 ------------AEKDGIRMSVGIRDLSGHETL-LLGSHEPYMPASTIKLAVVSALMQQVD -RGELSLADQVRVTPEDVVGGSGSLQTSFPQNLTLERLARLMITQSDNTATNVLIDKV-GM -DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-STKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535E3J0_9CHLR ------------LDRARGVTGLVVREVGGATLF-SQRSDETFPAASVIKIPLVMALYADAA -EGRLSLDERMPVGA--IVGGTGILGDLRDVRVSLRDLAMLAIALSDNTATNRLIDRL-GV -ARIDARMAEWGCVRTKLARGMFDWDAQ-RRGLENVVTPSEMAGLLERLVCGELVDRATSD -AVIAVLERCQD-DAMLRRYLAKGARTANKTGTLE-ATRNDAAIVFGPTRT-IVVAAFMRE -VA--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium SW_4_67_19 TaxID=1919115 RepID=A0A2T2UEF9_9BACT -----------------ASVAVAVR--ARAPTF-DWHADRVFHAASTMKVAVLIETYRRVE -RGALALDDALAVENCFRSAGGGVFYDHLGGALPVRTLTERMVTRSSNLATNLLVERL-GA -DAVERTARRLGAGTMRIRRGVEDRA-AYRAGLSNTASARDLAALMNALMRGEAVSPQADR -AMIETLAGQRY-NSMIPAGLPSDTRVAHKTGWLD-ALHHDAAIVCPPGEVPYVLVVFTEG -IRAH-SRSARLGAEIARAAH--- ->[subseq from] serine hydrolase n=1 Tax=Aminipila butyrica TaxID=433296 RepID=UPI0013A77DBA ---MLKQYINERLSTLEGHAGVYYKNLKTGETV-LTEGQDQFLAASIIKIWIMAEAFRQME -EGTIKKDQKIILRDSDKVPNNKMPYLHAESEWTVEDLCRLMIIISDNTATNILIRLL-GM -TNINELIQSLNMSKTRLNRSLFDTSKK----IENTISLEETGLFLEKLYREELISSKASQ -EMSAILQNQQN-NSKIPFFLP-QIPIAHKTGEDN-GIANDVGIIYSD--IPFILCFAAND -SY--TPAANQACQDIAKAAYQY- ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas stutzeri TaxID=316 RepID=A0A2S4ASY0_PSEST ---GLEQELRRIDDAAPGKLGVYIKHLGEDAEL-RYEAERFWYLGSAVKVPIAIAVLQGVD -DGDFRLDQQLSLEAEDKVDGSGLVWQDVGVDYAVRDLLNEMLIESDNTAANMLIRLV-GE -DDLNARTRKSMGSDFEAITTFTQV------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus kefiri TaxID=33962 RepID=A0A511DWN9_LACKE ---QIQHALQTCVNDASKKTSGYVKVIGDHQAI-HINGSRRQRSASDIKIFVMVEAFRQIK -AGTLHLNDMVSIPQDDKVGGTGQLANQDTNRLSCINLLNLMIKNSDNTATNVLIDKLGGL -APINKSIQELGCNNTRIQRKMLDYT-ALKAGRDNYTSADDVGKTLNAIYTGQLLGSNYDA -QMLQLLKGNAN-QSKIPALIRGSATIYNKTGEFDYGVQNDAAIIKHKNRA-FIAVVLSEN -GSQN------------------- ->[subseq from] VEB-1 n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=A0A125S0H4_ACIBA ------------------------------------------------------------- -------------------TWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFTDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPNGQLIFISVFVAE -SKETSEINEKIISDIAKITWNYy ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. ML3W TaxID=1538644 RepID=A0A088EVD0_9SPHI --tKLDRKLRELTQNFAGDIGIYVKNLKTQEEV-LIQADTVFPTASIVKVPILVGIFNKIE -RGELNLDQKFIYRSSQQYGGSGVMQFFKDSTTDLATMVALMITYSDNVASIWNQQLAGGG -ITINLLMDQLGLPNTKVNSRTEGRNEIWEKYGWGQTTPKEMATLVELLYKGKVVSPKASE -NMYRHLGNIFY-NDRSLSQIPANIKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKNNEAEDLTRKISHLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura hibisca TaxID=68565 RepID=UPI000836E841 -------HIERVFRDAGVTGHLYALDLDTGRDL-GVRGDDPVVLASVFKVPLLVAFHRRAA -AGLLDPTERVTLSPEERAPPTGIATMLDTVTLSLRDLTNLMITVSDNTAADAVFARV-GL -DAVNTAMADLGLSHTHLTGNGGELHDALDPSRTTRSTPREMARLLAMIWRDEAAPPEACA -EMRRLMGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS -FQAVLPEADAAIGTTARLAIE-- ->[subseq from] Beta-lactamase n=1 Tax=Prevotella disiens FB035-09AN TaxID=866771 RepID=E1KQY7_9BACT -------------------------IVNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAYICLPNNISYTLAVFVKD -FKGNESQASQYVAHISAVVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W1ATI9_9CHLR --------------GFAGVAGASVKDLSSGDGV-SVRGDEQFPTASTIKIHVLTQLFSRAE -RGELDLSKRIRLTSEMFGAGSGVIHYMENELLSLLDIATLMIIVSDNTATNMCIDLA-GI -EGTNELLDTMGLKSTKLRRKMMDSD-AIRRGDENVSTPNDLVAMLTLLYSGNP-SKKVAE -QVLHIIGKPKS--ATINRGVPSGLVVANKPGGMER-VRCDAGIVFLEKN-PYALSVMTNF -GLEDGVKQEGFIVEVVKEI---- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QH_2_67_10 TaxID=1919095 RepID=A0A2T2SGG3_9BACT -----------------ASVAVAVR--GRAPTF-DWHADRVFHAASTMKVAVLIETYRRVE -RGALALDDALAVENCFRSAGGGVFYDHLGGALPVRTLTERMVTRSSNLATNLLVERL-GA -DAVERTARRLGAGTMRIRRGVEDRA-AYRAGLSNTASARDLAALMNALMRGEAVSPQADR -AMIETLAGQRY-NSMIPAGLPSDTRVAHKTGWLD-ALHHDAAIVCPPGEVPYVLVVFTEG -IRAH-SRSARLGAEIARAAH--- ->[subseq from] Class A beta-lactamase n=1 Tax=Bacillus sp. AFS015802 TaxID=2033486 RepID=A0A2A8V9X7_9BACI ---MLEHSIQEIAERCDGMVSVAV-DLPSQ-AI-HINGDRPCSAASLIKIPILLEGFRQSE -KGMISLSEKVYVPKDERVGGAGVLTSLSENVLTIEDLLTLMIIVSDNTASNLLIDRL-GS -KPIQDLCHSLNLKQTKLMRKLMDFKA-MEQGLNNFTSAHDIITCLKVMDNGEQFSQTSRE -KMLNILQQQQF-DNKLPSRMDEKVFVANKTGELP-GVEHDCAILKFKNKT-AYIAVLIDE -LDE-NEYGKDTIARIGKLIFN-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. VT-16-64 TaxID=1917019 RepID=A0A1V2SFW7_9BACI ---TVEIRVKKLMEQAGGDWGIMIEDIQNDISW-GYEAHTPFPAESIIKIPIMAAVFSAAE -NRQLRLSDCVSMNQGDQVGGAGALQYVTPGILSIYDLLVLMIVQSDNTATNMLIDLV-GM -EAIQQTLLEAGMKNSHFQRKLMVYPAR--EHLQNIVTAADVSFMLRKMAAGQLVSRHACE -QMIQIMKWQQY-RNGLPSQLPPKWELAHKTGWDLN-RQHDAGILYTGQR-TMIISVLSEN -VS--SKTALDVLGEIGKAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-104 (HZI) TaxID=2486471 RepID=A0A3N2MHN2_9BACT ---SLQSELENYISEKNCRIGVAVIC--GDDTV-AVNGDEYFPMQSVFKFPQAVAVAAFCD -KNGIVPEDSVSIDSSMILRYSPLREHYGVVSIPIGELLEYSLVQSDNNACDILFDIIGST -AVADSVIKSMGFSDIDILHTEADMHLDTALCHKNRTTPVEMARFTEYFRNNLADSTPFMR -AVRQNLELCATGMSRIPADFEDGTLIAHKTGTGDISAVNDAGYIELPEGKSYSIAVFVAD -SPAGMEATEAIIGDISEIVR--- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A4U8VUJ7_9NOCA ---EVTERIRAVFADAGCTGWLHARRCGSAAEI-SVGGRDRVVTASVYKLVLFVAFCRRVD -AGLIDPRAQLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG -FVRAVMRKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A3D4JGT2_9CHLR ------------ISQFNKTISVSVYDLETNQEI-NIHADVMMHPASTMKVPVMMEIFRQSH -AGIFSLDDKIEIYNSSIVDGNDFDYARIGEKETIRELNRLMIVWSSNLATNILMDKV-GT -KPIDNFIKTLGIKDVNIMRLIED-NKAYRLGMNNTFSARGTTHMMRLIAEGKVISQEVCD -EMIQVMLGQEF-NESIPALLPKDVKVAHKTGWTGE-FFHDTGIVFPSIRKPYAITLFTNG -FPNDEFQAHNCMAEISKLIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. K20C18050901 TaxID=2291814 RepID=A0A3E1NYM9_9BACT --qQLEKGLRNVISGFRGDVGIYVRNLKTGHYA-EINADSVFPTASIVKIPILIGVFDKIE -KGELQYHQPLVYRDSAKYGGSGIMQYFKDSSTELSVLLALMMSYSDNTASLWNQALAGGG -ERINQLMEQYGMQVTRVNSRTAGRQEIWKIYGWGMTTPREMATLMLKIRNGEIISKSASE -RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAVDE-SRSEVVYVNAPHGE-YVFYIGTKN -IATDDNEASALIRKVSKYLWEYf ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium RBG_16_67_12 TaxID=1797288 RepID=A0A1F3CC62_9BACT ------EEIQALADCFSGTLGVWASLLDSGETL-EWNATDDFPAASTIKLPILYEVFRQAG -ECRFTLTDPMTLRAEDIVPGSGILKDLTPGLLPIRDLATLMIVISDNTATNMLIDLV-GL -DAVNGSCEALGLTGTVLAFKL---FRGPDGAPRNRSTPVDLGRLMTGVAGHAVLTPPACD -EVLAILGRQHF-TDLITRRLTPRVAVASKSGSIR-GTRNDVGLVSARGQ-RYVVAMMSKG -CADEDNEAAVLLPRVSAAIYRHf ->[subseq from] hypothetical protein n=1 Tax=Lactobacillus murinus TaxID=1622 RepID=UPI00096C57DC -------------------KTVYVAPMNEDTSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYHELLAYMIDESDNTAANIMIDALGGI -DKVNTQIEKMGAHDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNNEEQ--AA------------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5TE53_9BACT ----LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV -EYARNVLRDAHVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGNFLSSDSKE -QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EHDGRRETVAAISEAIFR-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia fusca TaxID=941183 RepID=UPI0007A7466A -----AERIRAVFADAGCTGRLHARRCDSDAEV-SIGGTERVVTASVYKLPLLLAYCRAVD -AGRLDPLARLTLIPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL -AAIHELLESLGLELTRLVGGTADIQRAYDPAYTSATTPEEMTRLLGALWRGEVLSGEQTD -FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Sulfopaludibacter sp. SbA6 TaxID=2043166 RepID=A0A2N9MQ10_9BACT ---PLQQAVKARIGDFQGTVSLYAKNLDTGAAL-GIRESEPVRTASTIKVPIMLAAFDAVS -RGQAKWGEPLTVAAAQMVSGSGILGSEMSDGLPLRDVVHLMIVLSDNTAANMVLERF-TA -DAVNAYLDMLGIRTTRALRKIRGDGGENEKYGIGVSTPRDMVTILEKLERGEIVSKDASR -EMMAILKRCQD-GSGIRRRMG-GLMVANKTGALD-ALRSDVGIVYSKNGR-IAMAITVDG -MPTPDNAGSLLIADLAKILVD-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5MA19_9BACT ----LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFV-GV -EYARNVLRDAHVEGVELRRGVED-HAAHERRINNEATANGLLTLLSA-VRGNFLSSDSKE -QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EHDGRRETVAAISEAIFR-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A524HAL1_9BACT ----LRSNLEAGVPPTGTEVGLALIDLGTGDSL-WINAQWRVHAASTMKVPVLIELAQRVD -VGQYGWEWPVLVKNESIVDSSSFQTLFAREGVTARELARLMITWSSNFATNLLVDQL-GA -SRIQATAWRLGADSIVVLRGVEDQK-AYDRGLSNTTTARDLAVLLAAIVEGRAASDSSTA -IMIDILTHQRF-RQGIPAGVPPGTRVASKTGGIT-GINHDAAVIYPTSRPPYVLVILTRG -FARP-TDAEAYMASISAEVW--- ->[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130DABCF -------ETIEKLKKLPGKISFYYRSLDSEDTA-EYQADQPLMAASVIKLFVMTEAFARIE -AGKLNPDAMITVKRADCVPSCGALNYHDNVQVTVMDLITLMIILSDNTATNVMIDLL-GI -DAINAQIRSLGFEKTVLKRKMFDSEKA-AQGLENYISAKEAGLLLEKMYRGTLISEKASA -KMIEILKNQRL-NHKIPFYIKGGPAIAHKTGEDS-GITHDCGIVFAEH--PFVVCFCGNE -T--DVTAYERTMAEIALEIYK-- ->[subseq from] Uncharacterized protein n=1 Tax=Oscillibacter sp. KLE 1745 TaxID=1226323 RepID=U2QQI6_9FIRM --------VKRQLSSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER -EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI -EFLNERFRALGLQETKIFRFLFDTEAA-RQGKENLCQPKEIGSLLEEIYHGRCVSANASE -RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVFVSNE -TD--VPAFEQVIRTVS------- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6AWT9_9BACT ---TLAKELDRLAAERKATIAVAVHDLETDFRF-SLRGDRWFHAASTIKVAVLLAVFRAAD -GGRLRLNDSLHVRNRFFSAAGGTVYQSIGRTAKISVLAHAMISGSSNLATNLLLDFL-GV -ECARTALRDARVEGVELRRGVEDH-AAHEQGINNQATADGLLSLLSAI-RSDFLSNESKQ -QVIRILLEQRF-NSMIPAGLPSHAMVAHKTGEIST-VSHDIGIVYLPEREPYITAILTEF -DP-DQEGRREAVAAISKAIYR-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia transvalensis TaxID=37333 RepID=UPI0012F67855 ---------------------------GSDAEI-SVGGGERVVVASVYKLPLLLAFCRQVD -AGRIDPTARLTVHPADCTPPTGLAVMRDPVTLSLRDLATSMMTVSDNAAADVLLGET-GL -GAVEELLDDLGLTRTRVIGGTADLHRAYDPSYTSATTPEEMTRLLRALWTGEVLSGEQTE -FVRSVMRHQVW-PHRIAAAFPRSVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPVVDAAIAETARIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus animalis KCTC 3501 = DSM 20602 TaxID=930942 RepID=A0A0R1ZX38_9LACO ---------------------VYVAPMNEDVSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTINLDDTYTLSNADKVGGTGVIQNMPAGKFTYRELLTYMIDESDNTAANIMIDALGGI -DKVNAQIEKMGAYDTKLQRKMMDTKS-LEAGRDNITSAADVGELLKKVYNHKLISKSDSA -EFLDILNKNRD-HDKLVRDLPTGAKVYNKTGIMQYGILNDAAIIENEKGA-FVVVVLTQN -GDNN-EERS-------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus antarcticus TaxID=238540 RepID=A0A3E0DUC5_9BACT ---DLQTTVQSQMDSIQGDVAVAFYNLSENDSL-LIKAGEELHAASTMKVPVMIELFKQAK -EGKINLDDSILLKNESIVDSSLYSYSKIGTTVALRDLMYSMITVSSNLVTNVLIELV-GA -KNVTATMRELGADKIEVLRGVEDTK-AYELGLSNSTTAKDLMIIMKAIADKTAGTETDCE -QMIAIMKDQQF-NTIIPFYLPENVKVAHKTGAIT-ALHHDAGIVYLPDGRSYVLVLLSKN -LK-DYDTGTEQLAGISKTVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=A0A3B8EAA5_LACBR ----------QTMGQLAGQNAVYIQ-TTGGQTL-SWRNRS-QKAASDIKLFILATVYRQVT -AGTFNLSAPYTLRAADKVGGTGNLQAQPDGTVTNRDLLRAMMTVSDNTATNIVIRRVGGL -SAVNQEIKRLGATQTVLRRKMMDQQ-ALAAGRDNVTSARDLGQLLMKLWQHRLISPTADA -AMLKLLAANTN-HTKLPRHVPAGRQVYNKTGEFDYGVENDAAIFAQGKRA-VVVVALSQH -GRLD------------------- ->[subseq from] serine hydrolase n=1 Tax=Echinicola rosea TaxID=1807691 RepID=UPI0010CA83F1 ---ELRETINTRLNKVEGDFAVAFRVMGEDPLTlLINEKETFHAASTMKTPVMIALYNQVA -MGNVSLDDSVKIVNESIVDGSPYRYSRIGQYSTYRELNYEMITMSSNLATNILIDKL-DA -KKITETMRSLGAMDIEVLRGVEDLK-AYERGLSNTTTAYDLMLIMEAIAARNAVSEEASL -AMFEVLKAQHF-NEIIPGQLPEEVVVAHKTGSIT-GVRHDSGIVQLPSGEKYVLILLSKN -LN-DPEEGIRAMSDVSKILYD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia rhamnosiphila TaxID=426716 RepID=UPI0004C3A324 -----AERIRAVFADAGCTGRLHARRCDSAAEI-SIGGTDRVVTASVYKLPLLLAYCRAVD -AGRLDPLARLTLTPSECTPPTGISALHDPVTMSRRDLATSMMTVSDNAAADLLLGEI-GL -AAIHELLESLGLALTRLVGGTADIQRAYDPAYTSATTPEEMTRLLTALWRGEVLSGEQTD -FARAVMRRQVW-PHRIAAGFPRGVAVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D0QHP2_9BACT ---VLQQNLETLVKGFKGDVGLYVRHLGTGQTA-AIQADTLFPTASMVKVPILCAVFDKIE -KGELKYNQQLLYRDS-LKYDDGITGSFRDSTIQLSEIVMLMITLSDNTAALWLQHLAGTG -TTINEWLENYGFHQTRVNSRTPGREAQRRVYQWAQTTPREMATLLTTIFQGRAVSPAASE -QMFRVLSKQYW-DAEGLSQIPPTVHAATKNGAVN-ASKSEVVLVNAPSGD-YVYCVITKN -QQEDDNEGNVMLRRVARMLWKYf ->[subseq from] serine hydrolase n=1 Tax=Halomonas sp. QHL1 TaxID=1123773 RepID=UPI0009F822D9 ------------------------------------------------------------- ------------------------------------------------------------- ----QALARALGVSTQSFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHPMDDLGDEQRQ -TLLALMQRTSSGKRRLKAGLGDSVSFAHKTGTQQR-RSCDAGIAERTAEGPWVIVTCTRG -PEA-VSAHERALARVGEAL---- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI000707450A ---EIVSKINQIGKKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLISFDDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL -EAVNNRVKDLGLNNTKILNKLMSFKTKTPEATRGYTTPNDMVKLLELLANGKVINPEISA -EIINIMKNNQD-YEMMKRYLPENVTVANKSGSIDR-MKADIGIVYAKCV-TYAVAIFCDE -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=D2BES4_STRRD ------------FRAAGVTGFLHAVDVDTGAEV-AHGADEPVVMASVFKLALLVEFFRQAD -AGRLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADALIGRV-GL -SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. CAG:226 TaxID=1262781 RepID=R5B6B2_9CLOT ------------LKAVPGNVGFYYKDLTSGETL-GYNENEQFEAASVIKLPVYMVIMKLAH -EGKLSLSEKLTCHHADKMPPCGALYFFTDEPVDIETLCGLMITISDNTATNMLISRL-GI -DFLNEEFKKIGLEKTHIERLLFDSEAS-AQGKCNYIVPAEMGMLLEQVYRRTFVSKEVSE -AIEKLLLEQQI-NHKIPGYLRDEVAVAHKTGEDDN-LTNDVGIVYAE--KPFVVSFASYN -TD--VPTAEIAIREISR------ ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0005BD889C ------------FRAAGVTGFLHAVDVDTGAEV-AHGADEPVVMASVFKLALLVEFFRQAD -AGRLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADALIGRV-GL -SAVNTMLAAEGLDGTWVEHDCRSLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Runella zeae TaxID=94255 RepID=UPI00055D9803 ---------------SKMRINIQVESLDGHVYF-SQQSQETVPSASVIKIPILVELMEQVK -AGRFQLEDKYLLADSDKVGGSGVLSKRMAGEMNIDELARLMMIASDNTATNVIIRKV-GR -ENINHRSKSLGLEGLQLNRVMMDTVA-VARGIDNYVTCRDINTLLRLIYHQKVATPMLCE -RMMGFLYENQD-TLTLPRLIPKHVKIAHKTGGLAY-VRGDAGIVFG--EVPFVISVFIRD -TK--VEEAEKMLGEIGEICF--- ->[subseq from] Beta-lactamase class A n=2 Tax=Nocardia ignorata TaxID=145285 RepID=A0A4R6PTZ2_9NOCA -------RIRAVFADAGCSGWLHARRCDSAAEI-SVGGRDRVVMASVYKLLLCVAFYREVD -HGRIDPAGRLTIDPADCTPPTGIAALHDPITLSRRDLVTSMMTVSDNAAADVLLGEL-GL -AAVTDMAAELGLTETRVVGGTADQHRAYDPAYASATTPEEMTRLLWRLWSGDVLSTESTE -FVRAVMRNQIW-PHRVAAGFPRGVVVAGKTGTVGI-IRNEVAVVEFPGEIPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. QHL1 TaxID=1123773 RepID=A0A1J8Q8E2_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- ----QALARALGVSTQSFTQDYDHAFDAYEATGENVGTLSAFGDLLASLHPMDDLGDEQRQ -TLLALMQRTSSGKRRLKAGLGDSVSFAHKTGTQQR-RSCDAGIAERTAEGPWVIVTCTRG -PEA-VSAHERALARVGEAL---- ->[subseq from] Serine hydrolase n=1 Tax=Rickettsiales endosymbiont of Stachyamoeba lipophora TaxID=2486578 RepID=A0A3Q8T5A0_9RICK ---DLTHLIHSLEKQYNAKIGVSITNVNHNVSY-HHRENEHFKMASTVKLPLAVYWLYLLE -HNKVNFDELVEIKPNDLVPGSGKLGYHPGFQISYRNIFEPMLTISDNTATDMIFKKVGGA -NNLRKFLINQGFNQIWVNRSIMGLFFQFHTDVRDTATPLQMNQLLINIANYKVINKQSFD -YLFDVMSRCSTSENRVKKWLPKGV-VIHKTGTWDYQYLGDVGYIQTRKG-MVAYSIYVET -KLQGNLVSEDIFAQLGKVIYENy ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. Bc-iso-3 TaxID=1848158 RepID=A0A1E3BVP8_9CLOT --aALESKLKKYISKYNCQFGIYFVDLESGSEF-GINAEEEYFAASTFKIPLNLYVYDRIR -EGIIDADTTLEYTEEDYEGGAGIIWSRESYGYTVRELLRLSIVYSDNVAVNMLLRYV-GK -ENVKNYMREMGGIVV--------------DDKKNLSCPRDMALYLKKVYELSENGDPLGK -ELVRNMVNTKF-YDRLPVLLPKNVKIAHKTGNLI-GVVHDVGIVYAK--RPYIIVVMTKN -VK-NERSANKAIANISKITYDY- ->[subseq from] Serine hydrolase n=1 Tax=Hungateiclostridium mesophilum TaxID=2487273 RepID=A0A4Q0IA86_9FIRM --aALESKLKKYISKYNCQFGIYFVDLESGSEF-GINAEEEYFAASTFKIPLNLYVYDRIR -EGIIDADTTLEYTEEDYEGGAGIIWSRESYGYTVRELLRLSIVYSDNVAVNMLLRYV-GK -ENVKNYMREMGGIVV--------------DDKKNLSCPRDMALYLKKVYELSENGDPLGK -ELVRNMVNTKF-YDRLPVLLPKNVKIAHKTGNLI-GVVHDVGIVYAK--RPYIIVVMTKN -VK-NERSANKAIANISKITYDY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0013F641C9 ------------------------------------------------------------- -------------------------------------LIEASMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] VWA domain-containing protein n=1 Tax=Clostridium sp. CL-6 TaxID=1499683 RepID=UPI00069464A2 ---KILEMVKNYTSNAEGRYSIYYGNVDMGFPM--IVNDASIRSASVIKIFIMIEALAQID ---KKLLDGNKLVTMNSCVGGTGVIQEHIGSQFTVYELLEYMMIDSDNTAANMLIDEVGGV -AVVNAKIKELGCVNSQMNRKLLDME-ALRNGQDNYVTVYDMGNILTKIYNKQCISEEADS -YMLQLMHRNKN-QNKIPYDLPENVNVFNKTGEFDYGVQNDVAIVETEKGA-YVLCVLTEG -GN--SQEEIGIIRRLSKDIYNEf ->[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus yavapaiensis KR-236 TaxID=694435 RepID=A0A318S7N1_9DEIO ---------ESLLARHPGAVSIIVRDAETGDLLfERSPDRPFHAASTIKVPLLVRALQRVD -EESLSLDERREMRSKDQVGGAGVLHELGPGLLTLRDLLTLMIIVSDNTATNIVIDLL-GI -DDVNAFLRAQGFTVTDLVGKLERHNERQRRGERNRANARELCELLYRLTRGTLLSPASTA -LALDILRRQQL-KDIIGRRAPRDFEIASKSGELR-GVHHDVGVVRTK--RPLVIAVLSDG -GEREHPENRELLAEVVSVLME-- ->[subseq from] Beta-lactamase n=2 Tax=Thermomicrobium roseum TaxID=500 RepID=B9L2F1_THERP -----QRTIEQLIGQVPARVMLLFRDLDEDLEI-AYDADRPVVAASTIKLLVLARLYRAFA -REQLDPRARVRIASDQVVPGSGVLRWLAEPPMTLRDLAVLMTIVSDNVAANALIDVL-GF -AAMEELVVELGLTGTALRRPFWGR-AAYPGEPENLVTARDLATLLAALELGHIVPEGHWD -DLRMLLRAQQF-RDIIPARLPEAVIVGNKTGTLL-GSVHDAALLWAPFGR-AVLVLLTSG -V-TDFEATRRALADLAKEVVDHw ->[subseq from] Uncharacterized protein n=1 Tax=bacterium SCN 62-11 TaxID=1660156 RepID=A0A1E4FNB1_9BACT --dKLKKTVQSLIARSGASTAVSIVDLQSNERV-DVQADEAYPLASVFKVPVMIELARQIQ -QSPLQLTTQLAMKASDRCIGSGSFQHRPVGTASLQQLVEWMETKSDNTATDMIFRRI-GL -TSVDTYLAGLGCTSSQI------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=bacterium SCN 62-11 TaxID=1660156 RepID=A0A1E4FNB1_9BACT ------------------------------------------------------------- ------------------------------------------------------------- --------QALEDRSARVQTSEENTLVA--TAVDNKLSSRDLALVLEKLYRGQLLDKKWTG -YCLGVLGRQTF-NTRLPRSLPREVKVYHKTGTIS-GVVNDVGVLELEPGRGLVVVVLVQQ -VQGDEGAADRLIGDIASVAYKAy ->[subseq from] Uncharacterized protein n=1 Tax=Klebsormidium nitens TaxID=105231 RepID=A0A1Y1HU06_KLENI --eELQRLVARQERKKKMHVGVVVEHLPSGERV-SINGREPFPLASVAKVPIIIAAAQQLQ -EAEVRLTTRLRVTEDVKCIGSGELHERPSGEATLGECMELACVVSDNTAADLVLQQA-TL -GRVRALLREQGLHHTDL------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] hypothetical protein n=1 Tax=Oceanobacillus manasiensis TaxID=586413 RepID=UPI000A568C87 ----LKASIQREIHE--AQAQYSILLTSRGESL-AINGDKIRPAASLAKIPILIEVCRQID -SGKLHPEKLVYIEEEQVVGGSGIISYLSNSNYSYLNLIELMIIVSDNTAANILLDSV-GI -DTVNHTVEKLGAKDTVIQRKFMDTEAQ-GLGQENYTTAKDMITLLKAITEGHYISSKSRE -FMKNILAKQQL-TNKLAKYIQPSVSIFHKTGELC-GVEHDVALLESNKE-KVYIAVLSDQ -LP-SNAEGQRTIAQIGKHVIDY- ->[subseq from] Serine hydrolase n=1 Tax=Pseudorhodoferax sp. Leaf274 TaxID=1736318 RepID=A0A0S9NIF0_9BURK ------------------------------------------------------------- ------------------------------------------------------------P -QRAEAVRRALDLPAGALRADIDTAYAGYYADGHNSATLVGYGAMLERLVRGELLSPASTE -RLFEAMKYGKRGDYRLEAGLPAQRRLIHKTGTQFE-RACHMGVVEPQDKHAVVLAVCAAG -L-DEQRAAGRLFEQVGAAI---- ->[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium TaxID=2044939 RepID=A0A2V2E8W6_9FIRM ------------LKAVPGNVGFYYKDLTSGETL-GYNENEQFEAASVIKLPVYMVIMKLAH -EGKLSLSEKLTCHHADKMPPCGALYFFTDEPVDIETLCGLMITISDNTATNMLISRL-GI -DFLNEEFKNIGLEKTHIERLLFDSEAS-AQGKCNYIVPAEMGMLLEQVYRRTFVSKEVSE -AIEKLLLEQQI-NHKIPGYLRDEVAVAHKTGEDDN-LTNDVGIVYAE--KPFVVSFASYN -TD--VPTAEIAIREISR------ ->[subseq from] Serine hydrolase n=1 Tax=Microbispora sp. Gxj-6 TaxID=2614688 RepID=A0A5J5KDW5_9ACTN ---------ERVFRGAGVTGWLHAVDVDGGREV-GLRAGESVVLASVFKLPLLLELYRQAE -RGLLDLAGLVRVPAEGRTRGTGLAAMLDDATLSLRDLAYLMMTVSDNAAADALLARV-GR -EAVNALLDRLGLTETRVVHDCRDMLTALDPARSNRSTPREMTRLLAMIWRDEAAGAASCA -AIRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LSQNQPRADAAIGAAARVAIDQ- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. B11 TaxID=2048899 RepID=A0A2G4JRD0_9CAUL ----------------------------------------------------AAAALAQIE -SGRLSAEEIIEIRDIDLSPRSAIAEAWPKRAYTLGELIERAVVDSDNTAADAVMKRIGGP -GVVTSWLEGKKVKGVSVDRYERQLQPAYLADRRDTATPIGAVRFLEALAQNELLSPAYSR -RLNALMTRSSTGLARLAAATPPGGTLAHKAGTGRTAATNDIGLYTLKDGRRIAVTVFLTG -STQDAAAREAVIAEVGGIVMA-- ->[subseq from] Serine hydrolase n=1 Tax=Bdellovibrionales bacterium TaxID=2053517 RepID=A0A3D3GBS9_9PROT ------------------------------------------------------------- ------------------------------------------------------------- -ARLNTFLRKLRITREELQSTIEDAFERYYRKNTNSGTLEAFGKLLENLFTGRLLNKVHTG -MLLEHLNRIETGEKRIKAGLHADTPFAQKTGTQIN-RICNVGIVHPKESEGWVVAACLEN -FQN-QSQAEKALTNLGQA----- ->[subseq from] Uncharacterized protein n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=A0A172YJ17_9GAMM ----LAPLVAQIDEEFPGELGFYLRDLDSGEYF-SLRAQEQWYLASMVKLPVALALLDMVD -RGEASLDERMTLNASDYVDGAGETNWHGPGTLRLGWLLEQMIIRSDNTATDMLIRRI-GI -ERVNARRAELVAHGFGEITTLADVRRAYYATGANSGRLDAHALLLERLQRLEALSTPSTV -HLLGVMSRVVTGEHRLKAGWPDSVGFAHKTGTQR-GRFCDGGIASRTVGTRRLVVVACTR -GSLSLADAERAMRELGAAAWR-- ->[subseq from] hypothetical protein n=1 Tax=Dechloromonas sp. Dech2017 TaxID=2570192 RepID=UPI0012928061 ----------------------------NGDLYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRN-DNKNLS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK -SKEEKEVAEVAEQ---------- ->[subseq from] Serine hydrolase n=1 Tax=Halomicronema excentricum str. Lakshadweep TaxID=2294035 RepID=A0A4Q7EAH1_9CYAN -----ETDLVALETMTGLTQSVFFYDLDSGNYI-ELNGTEPIAAASTIKVPILVAFLQAVD -AGTVRLDEAVILREDLMAGGSGFQTQEIGSQFTALEAATAMIVNSDNTATNMVIELLGGL -QVLNQQFANWGLSSTSLRNPLPDLDGT------NTTSAADLVRIMALVEQGDLLSRRSRD -RLLGIMQRTYN-RDLIPDGLGDSALTFNKTGDIGT-LLGDVALVDTVNGNRYLLSVLVDR -PFND-GRASELVRRVAG------ ->[subseq from] Beta-lactamase class A n=1 Tax=Psychrobacillus psychrodurans TaxID=126157 RepID=A0A1I4U0Q3_9BACI --eKLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE -RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV -ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHEMAIGGLVSNKASD -QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FIATVLSKD -ED--DLISKRILSQIGEEIYNY- ->[subseq from] serine hydrolase n=1 Tax=Caulobacter sp. 602-2 TaxID=2710887 RepID=UPI0013ED349A -heAMSHKLAAIAERAPGDLGVAVQDLTTAQRA-AVAGEQLFPLAGIWTAPLGAAVLAEVE -AKALSLRETITVEDVDLSPPSGVADAWPGRRWTVEELLKQAVAAGDNTAADVLMRRIGGP -GAVTAWLDLKKVENLRVDRYARQLLPDYLADTRDQTTPLAAVRFLEALNQGELTSQEDRR -RLLRMMEAAA--GDRLRPALPAGARLAAVTSATPAAADNTLAMVRLKDGRRFALAIFLKA -SPLEEADRDDLVLEVMRLVLQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Mediterranea sp. An20 TaxID=1965586 RepID=A0A1Y4HT44_9BACT ----LRQKIISYVAEKPAQIGVALV-VDSRDTI-CVNDACRYPLMSVFKLHQAMAVTRWLR -AHGTSLDFPVSLTPADLKPYSPLRDCYPQAGLPVGRLLTYTLQWSDNNACDILFDRTYSV -EQTDSCLHSWGLDHFSLSVNEDEMHDCPERCYDNWSTPLSVACLLEMLFTHPAFAGAEEA -FVRRQLQECATGRDRLAAPLETKALIAHKTGTSDRNGINDAAFVSLPDGRHYTLVVLVKD -SAASMEETCRYLADISAMVFA-- ->[subseq from] Uncharacterized protein n=1 Tax=Euryarchaeota archaeon RBG_19FT_COMBO_56_21 TaxID=1797983 RepID=A0A1F9ZZ06_9EURY ---KLRSEINKIARDVKGQFGLYLKHVESGKEV-AIDADKIFPLGSVFKIPVMMEVYRQAS -EGIVSLDEKLRLEPRYYCIGSGILQYLTPGLLTVRDLITLMIIATDNTASEMLWKRV-GI -QRVNMLMRELGLHKTSI------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656DCA2_9BACT ---TIVSKINQIGRKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL -DAVNNRMKELGLDNTKILNKLMSFKTKTPKAIRGYTTPNDMVKLLELLANGKIINPDVSA -EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] Serine hydrolase n=1 Tax=Pseudomonas zhaodongensis TaxID=1176257 RepID=A0A3M2HY73_9PSED ------------------------------------------------------------- ------------------------------------------------------------- ----EAVARVLNIPTSELKASMEQAYERYYARNLNASTLESYGRLLVKLAQGDLLSESSRD -LLFKDMKIDRYDAYRLEAGLPSEAAFIQKTGTQLE-RACHVGVIEPEKQADTIVIVACAE -ALDEDKEAGAAFEQVGKAITK-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535JFS0_9CHLR -----------ALASLPGEASAFASDAEGRALF-CVNEDEPFPSASVIKLPLVMTLYADAA -RGRLDLDEAAAVG--DRVDGSGVLRHMRDVELSLRDLAMLAIIVSDNTATNRLIERI-GL -DRVGERLREWGCPNTRLARKMYDFEAA-KHGRENVMTARETVSLLLRLHRGECEDRSTSD -AVLAVLEECQD-RTMLRRYLPYGLKVAHKTGTLDE-SRNDAAIV--PGERPALVAAFTRK -LRDTS------------------ ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=E5WSH7_9BACI ----IKAEILDLASCCEGRVAVYIHT--EDGVI-ETNADDVISSASLIKVPILLAGLSQAE -NALLDLNEEAEVKDAARVGGAGVLQAMSKGLMKVIDLMTLMVIVSDNTATNLIIERL-GI -EKINQFIKSLGFNCTELNRKMMDFE-ALKNGMDNTTTARDMVYGMKALAENSLLSGKFTE -KALDILEKQQYKNKLANTMDTEKVKVASKTGELP-GIEHDCAIFTHKGN-TVYAAVLVDQ -LR-SQAAGREVLSAIGSR----- ->[subseq from] Serine hydrolase n=3 Tax=Ignavibacteria TaxID=795747 RepID=A0A1G0X9T3_9BACT ---SLKIKIDSIFKSLEGDFSLAFKEVDNEKNLiLINEKMIFHAASTMKTPVMIEVFKQAA -ENKFNLDDPVEINNESIADGSPYYYKFIGKKKTIYDLVFDMITVSSNLATNILIELV-GA -KNVTETMRSIGANDIQVLRGVED-NKAFQLGLNNVVTAFDLMLIYENLVENKFASDSLTN -EMLNILLQQKH-NSRIPAKLPQDVKVAHKTGSIT-GVGHDSGIVFLSDGRKYVLVLLSKN -LK-DEKAVIEAEAEVSKIIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A2L2JWA9_9NOCA ----VTERIRAVFADAGCTGWLHARRCGGAAEI-SIDGRDRVVTASVYKLVLFVAFCRRVD -AGLIDPRAQLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG -FVRAVMRKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A561I3E3_9BACT --qKLEQGLRNVIAGFHGDVGIYVRNLRTGHYA-EINADTVFPTASIVKIPILVGVFDKIE -KGELQYHQPLVYRDSAKYGGSGIMQYFKDSSTDLSVLLALMMSYSDNTASLWNQALAGGG -ERINQLMEQYGMHVTRVNSRTAGRQEIWKIYGWGMTTPREMATLMVKIRNGEVISQSASE -RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAVDE-SRSEVVYVNAPHGE-YVFYVGTKN -IATDDNEASKLIIKVSKYLWDYf ->[subseq from] Beta-lactamase n=1 Tax=Microbispora sp. ATCC PTA-5024 TaxID=316330 RepID=W2EPP6_9ACTN -------AIEQVFRSAGVSGRLHVADIDGGAEV-AVGADEPVVLASVFKVPLVVELHRQAD -RGLLDLAERVRVPAEERTPGPTGLSAMLDGALSLRDLAYLMMAVSDNTAADVVLARV-GL -DAVNAMLAGLGLPGTRVEHDCRGLFAVLSPAHTNRGTPREMTRLLGMIWRDEAASPGSCA -AIRRLMGLQVW-PHRLSSGFPDDVAVSGKTGTLAT-LRNEVGVVEYPDGGRYAVAVFTRS -HGQNQPRADAAVGSAARIAIDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656DBG6_9BACT ---TIVSKINQIGKKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL -DAVNNRMKELGLDNTKILNKLMSFETKKKTPEAGYTTPNDMVKLLELLANGKIINPNVSA -EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2D6N8M2_9CHLR ------EALDRIAAQFPGRLGLYIEDLATGANH-EYGAGHRLPTASICKIPVMIELFRQAE -AGLLSLSERRRLSGDISTHGTGLLALLEDEPLTLYDYCRLMIGVSDNMATDLLLDVV-GV -SSVNTTLDALGFVNTRTSMTMGRCHYFQDGPQNNVTAPREMGAILGQLYRGQIVSAPASA -AMISLLKGCQH-RAMIPRHIAPDVAIAHKHGSSSR-IKGDVGIVFLPTGPLIIAALALAS -RGADGNAGADAIAEISRLTV--- ->[subseq from] serine hydrolase n=1 Tax=Psychrobacillus psychrodurans TaxID=126157 RepID=UPI000B874DC2 ---KLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE -RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV -ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHEMAIGGLVSNKASD -QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FIATVLSKD -ED--DLISKRILSQIGEEIYNY- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus firmus TaxID=1399 RepID=A0A0J5WAS1_BACFI --hTLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAIFSSASLIKVPILLAGLLQAE -KGLLQLEEEVEVTVSARVGGSGVLQAMARDLIKVTDLMTLMVIVSDNTATNLIIELL-GI -EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMAYGIKTLAEQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVIVANKTGELP-GIEHDCAIFTHKGK-TVCAAVLVDR -LQN-QAAGKEVLSAIGSRI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656D0A2_9BACT ---TIVSKINQIGRKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL -DAVNNRMKELGLDNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKIINPDVSA -EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] serine hydrolase n=1 Tax=Oscillibacter sp. PEA192 TaxID=2109687 RepID=UPI00135B7625 -------------SSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER -EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI -EFLNERFRALGLQETKIFRFLFDTEAA-RQGKENLCQPKEIGSLLEEIYHGRCVSANASE -RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVFVSNE -TD--VPAFEQVIRTVS------- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium QH_9_67_14 TaxID=1919102 RepID=A0A2T2SNQ1_9BACT -----------------ASVAVAVR--TRAPTF-DWHADRVFHAASTMKVAVLIETYRRVE -RGALALDDALAVENCFRSAGGGVFYDHLGGALPVRTLTERMVTCSSNLATNLLVERL-GA -DAVERTARRLGAGTMRIRRGVEDRA-AYRAGLSNTASARDLAALMNALMRGEAVSPQADR -AMIETLAGQRY-NSMIPAGLPSDTRVAHKTGWLD-ALHHDAAIVCPPGEVPYVLVVFTEG -IRAH-SRSARLGAEIARAAH--- ->[subseq from] serine hydrolase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI00126245E9 ------------------------------------------------------------- ----------------------------------------------------LVLEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase CTX-M-1 n=1 Tax=bacterium HR26 TaxID=2035421 RepID=A0A2H5YVF2_9BACT ---EMTSTVREAIERVPGRVNLLARDLDRDWEL-SYRAEVPVTAASVIKLLILAEAYRQFE -TGEAHPDEPVRVEPESWVGGSGVLRWLRPGLLTLRDLAVLMVIVSDNTASNLLIDRL-GF -ECINGLARRLGLEQTVLARKFLGRA-AQGNEPENLVSARDMAALLAALELGQIVPDPLLQ -DLRQILKAQQF-RDVIPGRLPAEAVIGNKTGSLP-GHAHDAAIIWAPAGR-LVLVLLSSG -LV-DQELGRRALCDLALACYRTw ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus sp. SSG-1 TaxID=1443669 RepID=UPI000B7FB254 ------------AEKDGIRMSVGIRDLSGHETL-LLGSREPYMPASTIKLAVVSALMKQVD -RGELSLADQVRVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM -DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALP-NAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. YIM 77859 TaxID=1540221 RepID=UPI000553364D ------------ARGYGGEVGILITDLAGRELY-ALQADRIFPAASTIKVPLLILALEEAQ -AGRLELGERVTLRAEDRVPGAGVLHELGAGLLTWEDLLTLMIVVSDNTATNLVMGRL-GI -ERVNTWLEERKLVGTRLVGLLEQQNAAQRRGERNHTTPRDQAALLGALTRGELLDPAHTE -RALAILTRQQF-RDLLGRHVPRDYRVASKSGELR-GLHHDVGVLFTP--RPLVAAVLSEG -GL--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8G1W3_9BACT --qRLQASIERTTRSVNATWGIWIKSLDTGEEI-AVDADRQMETMSTIKIPLMVEAFEQIK -ADTFKLTDKYTLVAEDIRPGTGIIQRLDPGALTVKDLITLMIIVSDNTATDVLYRMVGGP -AVVTRRMETMGLKKTQAVTNGAGWFAREGKHPFGLSTPREMGSLLEQMERGTLVDKAASD -AMLRIMRGQLY-RTRIPRYIT-GFTIPHKTGDFLPYVGDDVGMLEGQGK-TIIVSIFTAN -HFGSGEALENAIGLVAKEAADYf ->[subseq from] serine hydrolase n=1 Tax=Pedobacter indicus TaxID=2292082 RepID=UPI000E4C6D51 --kKLQKTLEELTKNHQGDVGVYVYHLKKHKEV-AINADTIFPTASVVKVPILIGLFKKIS -DGKYTLNQPMVYDDSRAYGGSGLMQFYKDSSTDLRTLASLMITYSDNTTSLWCQELAGGG -AEINKVMADIGLKDTRVNSRTEGREKIWEIYGWGQTTPREMASLLIKIRNGELIDKVASE -QMYRLMTSGFY-VDNAASQIPPYVQKASKTGAVD-ASRSELIMVNAPHGD-YVLYIGTKN -NKDRDNEASQLMRDISAAVWHHf ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriales bacterium CG_4_9_14_3_um_filter_34_10 TaxID=1974044 RepID=A0A2M7ZFJ8_9BACT -------------NQIEGDKAVFFLNLETGEEI-KFNEKEKFHAASTMKVPVMLELYRQAS -VGLFSLIDSIIVKNESIADGSSYKYDLIGKKLTVYELNHRMITKSSNLATNILIEFV-GV -DNIMKTMKSIGANDIRVLRGVEDIPA-YRKGMNNTTTAKDLCLVLKSILDYKVVNEKLSN -EILSVLEAQEH-NDIIPEQLPKNVKVAHKTGWIT-GVMHDAGVVILPDGRKYILVLLTKN -LT-NEEKSKKILQEISLEFYKYf ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A6B1CLJ6_9BACT ------AALRQIAAAFDGRMGWHIEDLATGQVH-QYRADERFPTASVIKIAVLVELFRQAE -AGRLSLDGRHRLRGDISTHGSGVLQIAQDEPLTLRDYARLMMGISDNIATDFLMGLL-GL -DQINATLDRLGCANVRAAATMGRYHYFGGSLENNVAAPGELASLLAAIYRGQVVSAAASK -AMIELLKTGRD-TRMIRCYLQPDVVVAHKYGSSGI-IKGDAGLVFLPAGPLVVVAFALAR -DD--GSAAAEAIAQVARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Marinobacter salicampi TaxID=435907 RepID=UPI0014092E56 ------------------------------------------------------------- -----------------------------------------------------------GN -ARYEMLLEKLGISKAQADASVQEAFERYYKRGINSGNLEAFGQLLERLVDGELLDDSHTE -RLLGYMAGITTGDNRIAGGLEDDVRFAHKTGTQV-ARSCDIGVLNPQVPDQAVVVAVCAE -DYDALSDAEKAYQAVGKALT--- ->[subseq from] Serine hydrolase n=2 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A3D4T9F6_9BACT --hRLTKQIQELIQGFRGETGVYVHDLEKNKVV-AINADSVFPTASMVKIPILVGVMDQIS -KGQLKYHQKLTYKDSLLYAGEDILGSFKSGEIELSKVMMLMLTTSDNTASLWLQSLGGTG -THINALMDSLGLQQTRVNSRTPGREANRNQYGWGQTTPAEMAKLMEMIVNKKVISAAASE -QMLRLLGRNYW-DEEALSQIPAGVFVASKNGAVN-ASRSEVLYVNGDDA-RYIFCICTKN -NQDQNNEAWVLTKKLSALLWKYy ->[subseq from] Serine hydrolase n=2 Tax=Oceanobacillus halophilus TaxID=930130 RepID=A0A495A1T4_9BACI -------------SEVSENFSICIHS--SNGNI-TINAENQKKAASIVKLFILVEAFRQKE -KGNLSFDDTVSIDKKRMVGGSGIITNLTESHYSYRNLIELMIIVSDNTASNVLLDKL-GI -NEINNLANQIGCEQTIITRKFMDYHAA-SKGFENYTSASDVCKLLQLLPKNNILSDNSRE -QILDILAKQQF-NHKLPSYFPEGTTFYHKTGEIT-GAEHDAGIFKNKQE-MIPIAVLSDG -WEEN-GRAQRYLAEIGRLIYKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Armatimonadetes bacterium DC TaxID=1661583 RepID=A0A0S4PM12_9BACT ---KLKARLDAICEKFRGVMGYSLFHKRYQHRI-HRLGDEIFPTASTIKVAVMSKAFEEID -AGRLGYTEKIPITPDDLRDGSGLLQFFKENQVEVRMLIHLMITVSDNTATIMLARRL-GT -VEVNKHLQRLGLKDTRLLALHPELKAYREKWGMGMCTPNEMVALLDAILTNRAGTPAACE -RMIRIMAHQYY-DDLIGSSVPPWVVCATKSGAISR-SRSDVGIVFALSGT-YILAVYTKE -AEAPDNEGEVAIRAVAHEVWKFy ->[subseq from] DUF3471 domain-containing protein (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q5RDR7_9BACT -------ILAELDKHPEGNFAIAYKDLGNGQTL-FLNERAVFHAASTMKTPVLIETYKQAA -AGKFRITDPILIKNESIVDGSLYSYEKLNSKLSIYEVLHRMITRSSNLATNLIIDLV-GA -DKANATMRLLGAKDIQVLRGVEDDK-AFEKGLNNTTTAYDLMIIMEALATGKVVSESASK -EMIRILMDQQF-HEKISKKLPPEVKVASKTGSII-AVSHDSGIIYLPDGRKYVLVLLSKG -VR-DLDDVNNTLANVSRLIYDY- ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus favisporus TaxID=221028 RepID=UPI0013D1B742 -------------EKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD -RGELSLADQVRVTPGDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM -DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALP-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus kribbensis TaxID=356658 RepID=UPI000411D4E8 ------EDLHKVLQTENGRISAAVEI--DGQLF-EHNVSLRMPSASLIKIPILLTAYRESE -RGSLHLDRPIQVPASSRAGGAGVIQALSDGILTVKDLLTLMIIVSDNTAANICIDLL-GM -RAINRTIDELGLSQTLLGRKMMDWA-AITEGRNNYTSAGDMLLCLKAITAGHYLSEESRN -EILSILEKQQF-QDKLPALMDNRVRAANKTGELP-GVEHDCAIIRFKDRT-AYAAILIEG -LRN-KIKGKKIISNIGKIIYD-- ->[subseq from] hypothetical protein n=1 Tax=Paenibacillus terrae TaxID=159743 RepID=UPI00119D6068 ------------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD -RGELSLADQVTVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM -DNVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALS-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7SWH2_9BACT ---ELEARFAELEALSGARLAIAISDFESGHDF-AYHADRWFHAASTIKLAVLVGVYGAIH -RGDLLPQSRVHVRNRFLSAGSPYRHREIGRTLRVSELAEHMIISSSNLATNLLLDLV-GL -DVLQRTLEEFGLQGIDLRRGVED-EAAFEHGISNRVTARGLVGLLRLMGEERAFTPELSR -QMLDILHRQQF-RSGIPAGLPREARVANKTGDIST-VAHDAGLVYLPDRKPYAIAVLTEW -EP-SATGRSTTIAAASYI----- ->[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. P3-120 TaxID=2024220 RepID=A0A255SFN6_9BACT ----------------------------NGELYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVNKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK -SKEEKEVAE-------------- ->[subseq from] serine hydrolase n=1 Tax=Collinsella aerofaciens TaxID=74426 RepID=UPI0010FF0E3B ---AIQQDIEALAEPYGGSVSVYAAALDLDGEV-AVVPDARRVAASIIKLPILACALETVA -AGELSLDEQITVTQQDIVGGSGSIQSRGAGVYSVDELLRVMIAQSDNVAANLVIGRL-GM -DAVNETCAALGLAQTVLARLMMDAEAQ-AQGRENYTSARDAAAVLQRLAAGTIATPELCE -RARGYLLAQED-ARGIVEGVSGVVLVAHKTGSLAN-AQHDAAIVYAE--RPYVLAILTQD -LD--REQALALERDISSVIY--- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. SCN 57-10 TaxID=1660094 RepID=A0A1E4LJ99_9CLOT ---------RSYADKTSAKLGFGFCDLASGASF-FLHGDDAFPAASAYKVWILAEVLRGAE -AGGYSMQDRLTLTREVKSLGSGVLYDLGEGLPTLLDYATLMMILSDNTATDVLFGYVGRD -NIKQNILDRYELAQTKCDWTCARLIEACTTEENDQTSPQDAVKTLRMAYEGTLVSPTVSA -EMLRIMKLCQT-NSRIPKHLPRGTEVAHKTGTIDR-VANDMGIVYTPKGD-YVLTLFYNG -NLANEED---------------- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LAV3_9BACT ---SLQTKVTAMAAQHHGKLALYAANLKTGESI-AIDPDTPVATASVIKLPLLFEAMEQVK -SGKHKLTDKIMLQKDDIVQGSGILQFFDTPLISLKDALTFMIIESDNTATNLVIDQV-GI -KNVNDRIAQIGLKDTYLYKKVFKPATDQKKFGLGKTTAREMAKVMEAIVRCDLQDQKLCD -DMLYMLRNQQY-RNLVPHYIETSSFIANKTGSLDE-VRNDVAVVYSKHG-PIIISAFTYD -NANNDNAAEMLVAHIAKLIMDAw ->[subseq from] Beta-lactamase n=1 Tax=Cyclobacterium amurskyense TaxID=320787 RepID=A0A0H4PA18_9BACT --kQLENEIRNLMDSVEGDFGLAFRLLDDAKEL-FINEKEVFHAASTMKTPVMIELFKQEK -AGNFSLQDSIVIRNESILDGSTFSYSRIGEKGSIYELMYEMIVNSSNLATNLLIEMV-AA -ENVNQTMRDLGANDIQVLRGVEDLK-AYDAGLSNTTTALDMMLVMEAIAENKVIGAK--- -NMMEILSDQHF-NGLIPKYLPKTAKVAHKTGSIT-GVQHDAAIVDLEDGSRYVLVVLSKN -LQ-DEEAGKACIARVSQLIYAY- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga ginsengisegetis TaxID=393003 RepID=A0A1T5P8I8_9BACT --hKLEKGLKDIITGFHGDVGIYVKNLRTGRYA-AINADTIFPTASIVKIPILVGVFDKIE -KGELKYHQPLIYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTASIWNQSLAGGG -QRINELMEQYGLAVTRVNSRTPGRAEIWKVYGWGMTTPREMATLLVKIRNGEVISKAASE -RMYRLMTHGYY-DETGLSAIPPYVQAAHKTGSLD-ASRSEVILVNEPRGE-YVFYVGTKN -NKTDDNEAQVLIKNVAAYLWKYf ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WP80_PSEUU ----LEQRLQAIDRSLGGGIGVHVLHMERNESY-GYRASEPWYLASGVKVPVAIAVLREVD -SGALSLDTELVLRADDFVDGDGATNRHRPGDLAVSWLLEQMLVHSDNTATDVLIRTV-GL -PAVNNVAAELVDSGLHI------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WP80_PSEUU ------------------------------------------------------------- ----------------------------------------------------------AGP -ARVRKLAQLLGVPLEELRQDLASAFEAYYATGANSAALVDYGRMLASLANGEVLGGDTNR -WLLEVMLRVQTGQRRLRAGLPAGIAFAHKTGTQFH-RTCDSGIAMQPRGSRVVIAACVRG -VG--TAAGERALRRIAAAITE-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI00033C6BE3 --eKVNADLDQTITPLRGINSVYVSPVDSNETI--VRNNHVQRSASAIKLYILVTAYAMDK -EGLFNLDEKHTIESDEKVGGTGVIRELPDGTLTYREILNDMITKSDNTGANIMIDALGGF -TIINNKIKAIGTQNTKLQRKMMDTA-ALEDGIDNDTSVQDMGETLKKLYNHDLVSKTADD -EMLAILANNQN-HTKLPASLPSEAKVYNKTGEYDYGVQNDAAIIANDKGA-FVVVVLSQD -GNE--QQQISAMSQLGSALY--- ->[subseq from] Beta-lactamase n=1 Tax=Solibacter usitatus (strain Ellin6076) TaxID=234267 RepID=Q01Y38_SOLUE ---PLQDAVRERIGNFQGTVSLYAKNLDTGASV-GIREALPVRTASTIKLPILLAVTDQVA -AGKAKWTEMLTVRPQDKVSGSGVIGAELSDGLPLRDVVHLMIVLSDNSATNMILERF-TA -DAVNAYLDKIGIKTTRSMRKVRGDGTENQKYGLGVSTPRDMVTILEKLERGEVVSPEASK -EILAVLKRCQD-NTGVRRKLT-GVSIANKTGALD-ALRSEVALVYAKGG-RIAIAITVDD -MPTPDNAGSLLIADLARILVD-- ->[subseq from] Abhydrolase_3 domain-containing protein n=1 Tax=Prevotella sp. P2-180 TaxID=2024224 RepID=A0A255TQ30_9BACT -----------------------------GDLYcGHQENSVFAMHSVMKFPQALYVADYLH -KKGLSLSDSVLVHKDSLDAWSPMMSKFEGARFTFAELIEWSLQQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMTRLLEWFYLHRN-DNKNLS -FIWNTMADCNTGKQRIAAVLPKGGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFSPK -SKEEKEVAEI------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Bacillus oleivorans TaxID=1448271 RepID=A0A285D5S2_9BACI -----GEKIKEIKEQCAGRLSVLI-DI-GEQKI-EADSEQIFLSASLIKIPILIAGFRQVE -QKILDPAELIYVPRDEKVGGSGVLATFSDPVLTVRDLLTLMITVSDNTATNILIDLI-GL -EAIQSCIKDLDLKSTILNRKLMDIESK-EKGIENSTSASDIVNCLKAIHRGSFLSHNSTQ -AVLSIMAQQQF-THKLPAYVDEKVKVFNKTGELD-GAEHDCMILTFGEKT-AYVAVLTDQ -LE-HNESGRQTIRQIGKHVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriae bacterium HGW-Ignavibacteriae-2 TaxID=2013809 RepID=A0A2N1VZV6_9BACT --nQLKTKIEQQIKNTQGSYAIAFMSLYNDDKM-YLNEREQFHAASTMKTPVMIEVFKQAE -ENKFNLQDSIILKNESIVDSSLYSYKYIGKNRTIYQLVYEMITVSSNLATNILIDLV-DA -RNVMQTMKLLGALDIKVLRGVEDIK-AYELGLNNTTTALDLAIIFKSLYQKKVISETACD -EMLNILFNQKH-KSILPFKLPADVKIAHKSGSIT-GVIHDSGIIYLPDGRAYVLVLLSKD -VK-DEAAGRMFLQDISKQIYDY- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. BMG51109 TaxID=1056816 RepID=UPI0004642E59 ----------------------------SAAEI-SVGGDERVVIASVYKLALLVAFCRHVD -AGRIDPTARLTVLPADCTPPTGIAVLRDPVTMSLRDLATSMMTVSDNAAADVLLGET-GL -GPVEELLNDLGLTRTRIVGGTADLHRSLVRDTDTHTTAEAFATLAE-------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Trichococcus sp. ES5 TaxID=872292 RepID=A0A143Y8M2_9LACT -----------RLESLPGKISCYYKDLVDGDSF-SYNSAEPMHAASIIKLFIMVEAFRRFE -AGSLDPKQKVAIRDHDRVPCGALTYLHDGIEVTVIDLVTLMIILSDNTATNVLIDLL-GF -AAINTTIHRLGYSETGLLRKMYDTEKS-AKGIQNLITAEEAGDLLERLHRGEIVSDQASA -QMLAILANQRL-NSKLPFYLKPTPKIAHKTGEDT-GITHDVGVVYPPAGHPFVLCFLGNG -T---------------------- ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TSY9_9BACT ------------------------------------GPAESVPSASIIKIPILVELMEQVK -AGKVNLDETYTLVAADKTGGSGVMASYPDGQMSLKEVARLMMIASDNTATNIFIRKL-GR -EKINDRMKLLGLASLQLNRVMMDTAA-VSRGIDNYVTARDINALLRLIYGHKVATPNLCE -QMMEFLFENRD-TVTLPRLIPKTIKIAHKTGGLTY-VRGDAGIVFAA--TPFVISVFVRG -TP--EKNAEKIIGEIGKICFKIf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UN25_9BACT ---SLRDAVEKIAGESKARVAVALLDFDSGLRF-SLAGDRWFHAASTIKVAVLLAVFRAVD -EGRLRLDDSLHVRNRFISAGFPFRYQAIGRTVNISALAEGMIAASSNLATNLLLDLV-GV -EYARNVLREAQVSGVELRRGVEDH-AAHERGIDNQVTADGLLTLLCA-VRGNFLSNESRE -HAIRILLAQRF-KSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPERQPYIAVILTEF -DS-ELDGRRETVAAISEVIH--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A2A2DBW4_9ACTN -----RGRVRAAFAEAGVTGWLHAVDIDSGDQL-DAGADQPVVTASVHKLCLLVALHQQAE -AGRLDLSEQITCPPRDRTPGPTGLAAMLDDVLSLRDAAYLMMAVSDNTAADLILERV-GL -DAVNHTTRRLGLTRTRAVHTFREFLTVLDPAATNRSTPRDMTRLLTAIWRDEACAPEHTA -AMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASAVLPPADAVIGAAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7VA16_9BACT ------DQLKKLADAHKGKVAISLKHLKTGESW-ALNSQTPMPTASLIKFPVMIEAYRQAA -EKKVSLDQMITLKKEDKVPGAGILTYDFTPGLALRDAIRLMIKFSDNTATNLVVDVI-GL -PSTAKTMIAMGYPNTQLHSKVYKRETSIALERSGSTTADEMIRLFEELNRGKLVSPEASK -EMYAHLLTCDD-NEKFPKFLPHGTKIAFKTGSVD-ASRTASGIFETASG-PVALCVLTTD -NEDKENAGNLLCAHAAKIVFDHy ->[subseq from] serine hydrolase n=1 Tax=Nocardia caishijiensis TaxID=184756 RepID=UPI00082D9F69 ----AADRIRAVFADAGCSGWVHARRCDSAAEI-SVGGWDRVVMASAYKLLVCVAFFREVD -RGRIDPTDRLTVDPADCTPPTGIAALRDPITLSRRDLVASMMTVSDNAAADVLLGEL-GL -AAVTDLAAELGLTETRVIGGTADQHRAYDPAYASATTPADMTTLLTQLWSGRVLSTQSTE -FVRSIMRDQIW-PHRIRAAFPRDVVVAGKTGTIGI-IRNEVAVVEFAGETPVAVAVFTRA -ARPDLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Oscillibacter sp. TaxID=876091 RepID=A0A1C5LMP8_9FIRM --------VKRQLSSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER -EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI -EFLNERFRALGLQETKIFRFLFDTEAACQG-KENLCQPKEIGSLLEEIYHGRCVSANASE -RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVFVSNE -TD--VPAFEQVIRTVS------- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZR96_9BACT ----LHEELETLALRNKARIGVALHDLETGFRF-SLCGDRWFHAASTIKVAVLLAVFRAAD -EGRLRLADSLHVRNRFFSAGSLFRYATIGRTAKISALAHAMICGSSNLATNLLLDFL-GV -EYARTVLREAQVDGVELRRGVEDH-SAHEQGINNEATADGLLKLLSAI-RGDFLTPESKR -EVIRVLLEQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDIGIVYLPEREPYIAAILTEF -DP-DTEGRRETVAAISEAIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A2N6AGB0_9FIRM --------VKRILKDIPGQTGFYYKRLDGSEIV-AFNEDRIFYAASLIKIPILIEAFNRVR -LGEMDFDKKYEVRNSDKVPCGALAYMHDGLEVTFRDLCVLMIIHSDNTAANMLIRIL-GM -DRINQTLIDREMYMTRLNRLLFDEE-ASAQGLENTAVLDELAMLFEEMHNGRLVSRKASI -EMLDIFKMQRL-NSKIPRLLPKGVPIAHKTGEDQ-GITHDIGIVYA--RKPFLIGFMSNN -TD--VVAMENAISEISRFAYK-- ->[subseq from] hypothetical protein n=1 Tax=Lactobacillus xiangfangensis TaxID=942150 RepID=UPI00070F9E10 ----VKQVVDQQMVALGGTSSVAVEPVTNGAVV-SHNRSQR--AASVIKLFILTTVYQQVA -DKKLNLDNTYQLKSSDKVGGTGTLQTLPNGSLTYKEITKRMIDESDNTAANIMIDTVGGL -RVVNQEISRLGLSQTKLGRHLMDTNA-LQAGKDNYTSVEDVAKLLKQMYNHQLVSKQADK -QMLAILKQNVN-HTKLPHDLPSDAIVYNKTGEYQYGVQNDAAIIKNRHGA-FVVVVLSQD -GKEQ--TQVAAMN---------- ->[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200) TaxID=937777 RepID=L0A686_DEIPD -----PKTIHALLSQHPGKVAIRVESLEGQLLL-SESDTHVFPSASIIKVPLLVRALQRVE -RGDFQLHDRIIMRSEERVTGSGILRDLDGDLLTLRDALTLMIIVSDNTATNLVIEQL-SI -DDVNAFLADEGMHDTALQVTPNRFTARQRAGERNRTTARDMTTLLGKLARGELLKPELTK -IALDILARQHY-KDILGRHVPTDYRVASKTGSLP-GVRHDVGIVWTP--EPLVLAVLSEG -GHHPDNHEVQLLARVARALLT-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RG96_9BACT ---TLAEELERLTAESKTRAAVAVHDLESGLRF-SLRGDRWFHAASTIKVAVTFAVFRAAD -DGWLRLDDSLHVRNRFISAGSPFHYGLIGRTAKVSVLAKEMISASSNLATNLLLDFV-GV -EYARKVLQDAQVSGVELRRGVED-HAAHEREINNEVTASGLLTLLSAI-RGDFLSNKSKE -QVIRILLEQRF-KSMIPAGLPPHATVAHKTGEIST-ACHDMGIVYLPERAPYIAVILTEF -DS-EREGRRETVAAISEAIYR-- ->[subseq from] Uncharacterized protein n=2 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5ZDG2_9BACT ---TLNEEVERLSAESNARIAVAAHDFESGLGF-SLRGERWFHAASTIKVAVLLAVFRAAD -EGRLHLDDSLHVRNRFISAGSPFRYQLIGRAAKISTLAEGMIATSSNLATNLLLDFV-GV -EYARHVLRDAQVDGVELRRGVEDH-AAHDKGINNEVTADGLVRLLSAV-RGDFLSNESKE -QAIRILLEQRF-NSMLPARLPVHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EGDGRREIVAAISEAIYR-- ->[subseq from] serine hydrolase n=1 Tax=Planobispora rosea TaxID=35762 RepID=UPI00083A0E19 -------EFDGLFRAAGVTGFLYAVDVDTGAEV-AYGADEPVVLASVFKIALLVEFFRQAD -RGALDPAERVTVMAGRHTPPTGVSAMTDDVTMSLRDLAYLMIAVSDNTAADTLIGRV-GL -GAVNTMLDGFGLARTRVEHDCATLFTVLDPARTNRSTPRETARLLAMIWRDEAASPESCA -WMRRLLGLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEAGVVEYPDGGCYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus furfuricola TaxID=1462575 RepID=UPI000F7B6427 ----------------GSTTSAYFYDLSSKQSA-TFGTDKQQRAASDIKLFIMATVYQSVK -DGKFYLNEKYALKDTDKVGGSGALQGMASGTIYYQDLLKYMMTQSDNTASNILLDKVGGI -SAVNNEIKKLGLTNSVMQRKLMDTKKL-TAGQDNMTTAKDLGKFLTKLYHHQVVSETADS -EMMRLLLQNTN-HSKLPAQVASDVKVYNKTGEFSYGVQNDAAIMEKGGK-AFVIVVLSQN -GTEATQ----------------- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus xiangfangensis TaxID=942150 RepID=A0A0R2LZV4_9LACO ----VKQVVDQQMVALGGTSSVAVEPVTNGAVV-SHNRSQR--AASVIKLFILTTVYQQVA -DKKLNLDNTYQLKSSDKVGGTGTLQTLPNGSLTYKEITKRMIDESDNTAANIMIDTVGGL -RVVNQEISRLGLSQTKLGRHLMDTNA-LQAGKDNYTSVEDVAKLLKQMYNHQLVSKQADK -QMLAILKQNVN-HTKLPHDLPSDAIVYNKTGEYQYGVQNDAAIIKNRHGA-FVVVVLSQD -GKEQ--TQVAAMN---------- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Gemmatimonadetes TaxID=234665 RepID=A0A1Q7R3J8_9BACT ----VRERLAARVAQAPATVGLYYRSLTHPDSL-LLDANVRFHAASTMKLPVLIQVFRDAD -AGLLRLDDSLTVHVVSLVDASPFDYGRVGRPASVRDLLELMITRSSNLATNILVERV-GA -GRAQASARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQNRAASPASCR -EMLRILEAQEF-NEGIPVGLPPGTRVAHKTGWIGEVVYHDAAVVYRSSGGSYVLVVLTGG -IKQD-SVAHNLVADLSRLVY--- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudoxanthomonas taiwanensis J19 TaxID=935569 RepID=A0A562DJ30_9GAMM ---ALEPRLRAIEAALGAGIGVYVLHMERDESY-GYRAGEPWYLASGVKVPVAIAVLREVE -RGTLALDTPVVLRADDFVDGAGATNRHRPGELALSWLLEQMIVHSDNTATDVLIRTV-GL -AAVNRVAAELVDARLRIT------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudoxanthomonas taiwanensis J19 TaxID=935569 RepID=A0A562DJ30_9GAMM ------------------------------------------------------------- ----------------------------------------------------------AGP -ARVRKLAALLGVPPEQLRQDLAAAFEAYYATGANSATLVDYGRMLATLADGKALGAEATG -WLLERMLRVETGHRRLRAGLPPGIAFAHKTGTQYR-RTCDLGIAMQPDPARVVVAACVRG -IG--TAAGVHALQRIAAAI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Paenisporosarcina quisquiliarum TaxID=365346 RepID=A0A1H8FJN3_9BACL --eKLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE -RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV -ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHGMAIGGLVSNKASD -QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FVATVLSKD -ED--DLISKRILSQIGEEIYNY- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000D492D05 ------------------------------------------------------------- -------NKTVTIKESDIVAYSPVTERYVGKTMTLHQLISAAMLQSDNTASNIIMEQLGGL -DQISSRLQALGDTTTNPQRYEPELNNYDPQSTADTSTPRATAHSLQQLLTTDAVAPQQRK -FLQNLMFNNETGDSLIKKGVPDSYKVGDKSGQGTYGTRN--------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6K4P1_9BACT ---TFNEEVERLSAESKARIAVAAHDFESGLGF-SLRGDRWFHAASTIKVAVLLAVFRAAD -EGRLQLDDSLHVRNRFISAGSPFRYQSIGRTAKISTLAEGMIASSSNLATNLLLDFV-GV -EYARRVLRDAQVDGVELRRGVEDH-AAHDRGINNEVTANGLVSLLSAL-RGDFLRNESKE -KAIRILLEQRF-NSMLPARLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EGNGRREIVAAISEAIYR-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Verrucomicrobia (miscellaneous) TaxID=417295 RepID=A0A1Q7TDQ2_9BACT ------------------ATAVSVHDLESGLRF-SLRGDRWFHAASTIKVGVLLALFRAVD -EGRVRLDDSLHVRNHFFSAGSPFQYQAIGRTAKIAALAAGMITASSNLATNLLLDFL-GV -AYARNVLRDAQVQGVELRRGVED-HAAHEKSINNEATADGLVALLSAL-RGDFLRSESKE -QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EREGRRETVAAISEAIYH-- ->[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. JW-3 TaxID=2497877 RepID=UPI00101C7ADA ----LSRLLEAELSRLPTRSGIYVKHLGTGEEA-SVRGNDEFESASTIKLATMVLAFRMAD -ERKLDLSQRYVIKPADYRGGSGIFRFHDPGMPTLRDIITQMVITSDNTATDIMIARVGGK -EVVNRFLRDAGYQVLRQNNTTLEFFRSAKANWFGWATPREMGRLLESIELNTAASKASCE -EMKRILLAQQSGIIKLPHYLT--VPIGHKTGETGT-VTNDVGMIYAHSGT-IVISFYNVE -LAGPRAETEDGMGRVARTVVDYf ->[subseq from] serine hydrolase n=1 Tax=Nocardia higoensis TaxID=228599 RepID=UPI000688466E ------------------------------AEI-SVGGHARVVTASVYKLVVLIAFCRAVD -AGTIDPAARLTIDPAECTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEV-GL -GAVEDVLTDLGLTETRIVGGTADVHRAYDPAYTSATTPEEMTRLLRALWSGRVLSPEQTA -FVRAVMAKQVW-PHRITAAFPRGVTVAGKTGTIGV-IRNEVAVVEFPHEYPVAVAVFTRA -ARADLPVVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium daejeonense TaxID=371142 RepID=A0A4U9K0N3_9SPHI --kSLEQKINQAIEGFQGDIGVYVKHLKKNKEV-AIHADSIFPTASIVKVPLLVGVFQKIK -NGELRLDQKFLYRESRAYGGSGLMQFFKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG -QTINPILDELGLKNTKVNSRTPGREEIWKKYGWGQTTPREMSKLFELIREGKVVSSEHSD -KMYRFLKNQFY-NERSLSQFPAIINMISKTGSLDD-ARGEIVLVNAPHGD-FVFTILTKN -NKTNENEAENLTRKIANIIWNHy ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. J33 TaxID=935836 RepID=UPI00047C2A47 --hDLEAEVLELACSCKGRISLYIET--EEGII-QKNSDEIFSSASLIKVPILLAGLSQAE -KGLLQLTEELEVADHARVGGSGVLQTMSKGLLSAIDLMTLMIVVSDNTAANLVIDLI-GK -ENINGWIKGCKLNSTELNRKMMDFE-ALKKGFDNKTTARDMANCLKSLAEHSLLSGEHTD -LALRILDAQQF-KNKLANYIDENVQVASKTGELP-GVEHDCAIFTRKGR--MAIAAVLAD -QLKDQEAGREVLSSIGRRICR-- ->[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Lactobacillus allii TaxID=1847728 RepID=A0A1P8Q5U4_9LACO ----IKQVINTNLSGLKGTTSVAVASTTNQAKV--VQNNQSQRAASLIKLFILITAYQQAN -SKELNLDDTYTLSATDKVGGTGTIQGLPTGSLSYREILKRMMDESDNTAANIMIDKIGGI -STINAEIERLDLNDTQLERKMMDTD-ALADGKDNYTSVTDVATVLSKIYAGNLISQKADR -AMLTIMHQNAN-HAKLPHDLPSDATVYNKTGEYDYGVQNDAAIIKNNHGA-FVVVVLSQD -GNESEQ--V-------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Chitinophaga eiseniae TaxID=634771 RepID=A0A1T4SUA7_9BACT --kQLYDKLAPLLAAHHGQAGVYVHHLKTGRTV-AINADTVFPTASMIKMAIQVGVFHQLQ -EGTLQYRQLLTYRDSLLYPGEDILGAFRDSQITLDKVVMLMLTMSDNTASLWLQALAGGG -AQINTWLEGHGFVHTRVNSRTPGRAGDWKIYGWGQTTPREMGTLMEQIYKGEVVSHAASE -RMYRNLTRNFWDAEGL-RMVPPDVRTASKNGAVD-ASRSEVVLVNAPHGD-YVYCIITKN -NADRDNEAWELLRKVGSAIWQHy ->[subseq from] serine hydrolase n=1 Tax=Salinicola lusitanus TaxID=1949085 RepID=UPI000DA1EB17 ---------------GTGEIGVHVRRLDDGERV-GWRDAERWYWASLVKVPVAVELLDRIS -RDGADLDDTMTLHASDYVDGAGATNWAAPDTIPLRTLLERMLIDSDNTATDMLMRRV-GL -EAVNRRARSLTDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIDEGEALPAAATA -TLLSIMQRADTGHRRLAAGFQRQWPFAQKTGTQYS-RFCDAGILAPGTPGAVVIVSCLRD -AP-SRREAERTFQAIGRAV---- ->[subseq from] serine hydrolase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI001261B838 ------------------------------------------------------------- ----------------------------------------------------LVLEKIGGP -AALTAYLQSVGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGVQIADRSGAGGFGSRGITGLVWSAQQEPMFVSIYLTQ -TEATFDERNAAIVTIGKSIFDTf ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A380X8D7_BACFI ---TLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAIFSSASLIKVPILLAGLLQAE -KGLLQLEEEVEVAASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELL-GI -EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMVYGIKALAEQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVKVAGKTGELP-GIEHDCAIFTHKRK-TVCAAVLVDG -LQN-QAAGKEVLSAIGSRI---- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 187-3 TaxID=2486017 RepID=UPI000F73E2A2 ---KIKTDIQTTVGTISGLTSVYVAPTTGSQQV--VIDNQQQRAASSIKLFILAAAYSQVN -RGQLNLSELHTLSSAEIVGGTGLVQNAVGTQLSYQDLLTRMIQDSDNTATNIVIDKLGGL -NVVNQVAAQLGAKDTQLQRKMLDTQT-LAAGKDNLTTVQDIGNLLTKLYKHQLISKPADD -AMLGILATTKN-HSKLPQSLPAGTTVYNKTGEYDYGVQNDAAIIKNEKGA-FVVVVLAQN -GVES--QQVTAMNKLGALLY--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7X1C4_9BACT ---HLRARVQDAEKRLDGVLGLSVKDLKTGTSF-EVRADEVFPQASSIKLAVLYELYRQAD -EGKIDLGQV-TRPPLPRVKGGGVLQELGDKVLTWRDLAVMMVGWSDNEATNVLISRL-GM -PAVNHRLEDLDLDHTRLRRKMMDLEAARRG-DENVGTPSEMRRLVEASYTGKGLSPAAAR -DIRAVLATPKD--SPFRVPLPETLVVMDKPGSLE-AVRCVTAVVDVPGR-PYAVSIETTF -LKKD-EDGAAAIREISAALYEMf ->[subseq from] serine hydrolase n=1 Tax=Paenisporosarcina quisquiliarum TaxID=365346 RepID=UPI000B89E8D1 ---KLVSRIEKLIVPSKGTWGIVLEDLNSGEKW-EHNEQELFYAASVIKLPIMASVYSAVE -RGDLALTDLIILDEQDYVGGSGVIQHFTPGSLPLKDIIMLMIIQSDNTATNLLIDLV-GV -ESIQNTMKEVGMVYSTFLNKLMLSKPNPK--GANCIAAVDISVLLHGMAIGGLVSNKASD -QMVDVMKKQQV-RDCLPEKLPAPWELANKTGWIP-GTRHDVGIFYVGDRE-FVATVLSKD -ED--DLISKRILSQIGEEIYNY- ->[subseq from] Beta-lactamase n=1 Tax=Saprospira grandis DSM 2844 TaxID=694433 RepID=J0P864_9BACT --qALEDSLRAICQNPKGQMGIYVYDAQLDKSF-SIAGDTLFPLASVYKLPIVASLLAAQE -AGKLSLFDSIRLNLEDRRHSGCFMDWDTTGKPKIEDLALYMMRYSDNCATDALLRQLGGP -EFVQAQLKSWMVSDININRYLIEIFIKFLWDRRDQGSPKAFVHLLKGLDQEHWLNANSSQ -WLRDCLLSCRTGRYFLPKVLPPNRQVAHKTGSLP-GIYNDAGWIEREAGRPIYYAVFLKN -AFGKPKKERARIAAAMK------ ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga terrae Kim and Jung 2007 TaxID=408074 RepID=A0A1H4GEN8_9BACT --kSLQQAISAAVAGFKGDVGVYVCQLSTGKYA-AINADTIFPTASIVKIPLLVGLFDKID -KGELQYHQTLWYRDSIRYGGSGIMQFFKDSTTELSVLAALMMAYSDNTSSLWNQSLAGGG -VTINKILEQYGLKDTRVNSRTPGREQDWKKYGWGQTTPREMASLLVKIRKQEVISPKASD -RMYRLMTKGYY-DEGAISQIPAWVQVADKTGSIDD-SKSEVLLVNAPHGD-YVLYIGTKN -IQADDNEAVVLIRRISAIVWKHf ->[subseq from] Beta-lactamase n=1 Tax=Acetonema longum DSM 6540 TaxID=1009370 RepID=F7NMC7_9FIRM ----------DRIQKEPGFYSLAVSLPDTQDRI-SINS-RRMSSASLIKIYIMTETLRQAK -EGILALDELLTVTAANRVGGAGELEFAAYGSYTILHLVEVMITESDNTATNLLIDRI-GM -DSVNRCMAGLNAADTELARRMMDFAAR-QEGRDNYTSVTDMVSVLERLYHRCCLDPFCDS -VMLAILKQQQD-RVKIPLYLPPGTVVAHKTGELDY-TEHDAGIVYGSKH-SYAVAIMAEQ -LM-DVAYGRHVIANMSKLIFEY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus indicus TaxID=246786 RepID=UPI00068E2288 ------KNAADILSSCPGRAGACFSW--NGEWL-EAGSSDVFSSASLIKLPILLTAFRLAE -KGNLDLNEKVKLRDVEKTGGAGVLQALSEDALSVQDLLTLMITVSDNAATNWVIEKI-GM -TKINETIEGLGLVDTKLNRKMMDLD-AIQSGMDNFTSPADMVRCLQAINEGDFVSEDSRQ -KMLAILQKQQF-TDKLPYNMDKDLIAGNKTGELP-GIEHDCAIIKYRDTT-VYAAVMIDQ -LEQ-KEWGRKTISEVGKLIYEK- ->[subseq from] Serine hydrolase n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q3LDF9_9BURK -------------DANASAIAVAAYDFEHHTTW-SLNPARWFHAASTIKVPVLLGVYEAIE -QRRFEPYSRVHVRNRGVVDGRPFREVHAAIGLTVHELAEHMIVTSSNLATNVLLDLV-GV -EAARASLARLHLGGIDLQRGVEDE-VAWEAGINNRVTAAGLCDALRLIEEGKAISPEASK -AMLDILHQQRF-RSGIPAGLPEDARVAHKTGEIST-VAHDAGIVYLDGRDAYVVVILTEW -AP-DVSGRQETIARISRAVYG-- ->[subseq from] Serine hydrolase n=2 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653V1K3_9GAMM ---DLDRRVRAIDARFAGELGVHVQRLDDDGAY-DFRGDEIWYLASGVKVPIAIAVLREIE -QGWLTLDTPITLLDTDFVDGAGRTNAHRAGDLAIGWLLEQMIIHSDNTASDVLIRTV-GL -GQVNAVASELIARDVRIT------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Luteimonas sp. 9C TaxID=2653148 RepID=A0A653V1K3_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GQ -ARVRTLAQRLGV--TPADFLLPDLDSSYYATHVNSATLRDYGHMLAALQEGRALDLHRTR -YLLDVMARVQTGRQRLRAGLPPDARFAHKTGTQYR-RICDSGIASVPARQPHVVIAACAR -GAG-TVASERALRELGAAVT--- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A351C4E3_9BACT ---DMTGDIQTIIADYGATVAVSILDASKGFEL-HMDADRLFHAASTMKVPVLIELYRQAE -SGRFSLSDEVLLKNESIVDGSLFQYEQLGTPMALEQLAYNMITVSSNLATNLLIDFL-SA -DSVQTTSERLGTTHMQTIRGVEDLKA-FDLGMSNKATSRDLALLMELLRTGTAVSVESDA -AMREILNNQVF-QTMIPSGLPAGVRAAHKTGSIT-AIHHDAAIIYPPDSEPFVLVIMIQG -LQ-DHEASSLLGSEITRYVYK-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7G417_9CHLR ---KLEDDLIDKLDQFPGVAGVSIKDLISGNDI-SINGNEIFPTASIIKIHILTYLLKMAE -SGSIDINKRISVDKNEFTGGTGILKYLKGKPLTLRDIAVLMIMLSDNTATNICIDLL-GI -ENINSFISDMELSSTKLNRKMMDEK-AIIQGNENLSTPKELTKMLEKLYLG-LPSKAVSK -DVLQIMSEPKN--SCLNLSTPSDITVANKGGGMEH-VRGDSGIVFLENN-PYIISILTKS -CYKGSGFQEKYIVNIAKDVFEIf ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5LBL3_9BACT ----LNEELETLSSESKARIAVALHDLESGLRF-SLHGDRWFHAASTIKVAVLLAIFRAAD -EDRLRLDDSLHVRNRFISAGSSFHYQAIGRTAKISALAEGMIASSSNLATNLLLDFL-GV -EYARNVLRDAHVEGVELRRGVEDH-AAHERGINNEATANGLLTLLSA-VRGNFLSSDSKE -QAIRILLQQRF-RSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EHDGRRETVAAISEAIFR-- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=UPI001158CBF1 --rKLEKGLRKIVAGFNGEVGIYVKNLRTGRYA-GINADTIFPTASIVKIPILVGIFDKIE -KGELKYHQPLIYRDSIKYGGSGLMQFFRDSTTELSVLLALMMSYSDNTASIWNQALAGGG -QRINELMERYGLAVTRVNSRTPGREGIWKVYGWGMTTPREMATLLVKIRNGEVVSKAASE -RMYRLMTHGYY-DETGLSRIPPYVQAAHKTGSLD-ASRSEVILVNAPRGE-YVFYVGTKN -NKTDDNEAQTLIRNISAYLWNYf ->[subseq from] serine hydrolase n=1 Tax=Nocardia flavorosea TaxID=53429 RepID=UPI0007A4FB00 ----VAERIHAVFADAGCTGRLHARRCDGGAAEvSIGGTERVVTASVYKLPLLLAYCRAVD -AGRIDPLERLTLIPAECTPPTGISALHDPVTMSRRDLATSMMTLSDNAAADLLLGEI-GL -AEVHDLLQSLGLLRTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGEVVSAEQTA -FAQAVMRRQVW-PHRIAAGFPRGVSVAGKTGTIGI-IRNEIAVVEFPEEYPVAVAVFTRA -ARADVPAVDAAIAEAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium scatologenes TaxID=1548 RepID=A0A0E3GQJ0_CLOSL -----EELLKNSLKNSESKYSLAVKNLKSKEIC-YMNVHEVVPSASIIKLFIMAEAFNENK -MGKLNLHDMIKIDNDKKVPFSIVSLLNSVEQYSIKDLITLMIIQSDNTAANVLIDFL-GI -DNINNFIKKTGFKNTILGRKMMDFEGD-KGGKDNYTSAYDIFLFLEKLYNNNLVGEKEDK -FMIDILSHQLD-FSMMRMDMLDDLKIAHKTGDLNC-LKHDVGIVYSEKVGDYIFVMFTYE -AK-SDGYARKLICKTSKQIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus invocatus TaxID=173959 RepID=A0A3M8BV51_9BACL --eTLQGRLEQIIRNAQGTWGVVVEEIGEGICF-EHLPDKLFIAESVIKVPIMAAVFAQAH -QGAFSLDDRLPLRREDLVKGSGLLFALSPGLLSIRELVTLMIIQSDNTATNILIDLV-GK -ECVDQTMLELGMEQSKYVRKLMIYPAD--IDANNRITAGDVARMLNRLATGRFIHAHACE -DMVAIMKKQQF-RNGLPSMLPTDWEIASKSGWDT-GRQHDVGLLYTQGR-CFAITALSQD -VEAE--EALHT------------ ->[subseq from] Serine hydrolase n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A520H901_9BURK ---RLQAELSNIRADPHGAVGVHVRDLDTGLTV-SQHLDRPWYLASMVKVPVAIAVMRGID -AGHFRLDTPLTVRASDYVDGAGPTNKQPGKSLSVRFLLDQMIIQSDNMATDMLIGLV-GV -AEVNALVDTLVPDGFGRITTLGEVRRAYYASGLNTGRLEAYAALLALLADGKALSPKSTA -HLLKVMTRVATGTHRLKAGLPSDVGFAHKTGTQRR-RICDAGLIRAVDSERRVVVVACVR -DVLPLERAEAALMQVGAALCK-- ->[subseq from] SLH domain-containing protein n=1 Tax=Paenibacillus sp. XY044 TaxID=2026089 RepID=A0A259TBR0_9BACL ----------------GIRMTVGIRDLSGYETL-LLGSGEPYMPASTIKLAVVSALMQQVD -RGERSLTDQVTVTPEDVVGGSGSLQTNFPQNLTLERLARLMITQSDNTATNVLIDKV-GM -DRVQQLMDQLDLRTMHLGRKMFAAA--PSPAQDNFIDAADLTELLGQIYQGSFLSISSRN -QIIAWMARQEV-NTKFGAALP-DAPVAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQQVAKAVYG-- ->[subseq from] Beta-lactamase class A n=2 Tax=Maledivibacter halophilus TaxID=36842 RepID=A0A1T5M6Z3_9CLOT ----LRKTIDDLIKDAEGDVSVIIKNPKENESI-MINEDTVFPAASVIKLYILWELFERIE -KGEFTLEQEISIEDKDKVDGFGILKEHSGIKLSVKDLATLMIVLSDNTATNMLIDLL-GM -DNINRTIENNKLKHTVLQRKMMDGKAK-EKGLDNYTSSIDVLKILEKSLQK--------K -EIIDILKRQQC-NNKLPVLMGDSMELAHKTGDLP-GVEHDAGILFIKEEA-VFIIVLTKN -LK-NNIEGIKLNNNIGKAVYDYy ->[subseq from] Serine hydrolase n=1 Tax=Anaerolineae bacterium TaxID=2052143 RepID=A0A350WMD6_9CHLR -------NLESFIAQFEGTVSVSVQDLETGKGI-FINADVSMHPASTMKVPVMMEVFRQAE -AELLSLDESLKIFNSSIVDGSEFSYTRIGKSESIRELNRLMIVRSSNLATNLLMERV-TC -ASVDALIKELGIANMTVIRGLEDKK-AYRLNINNSASARSSTQMMKLIAEGKVVSRNVCD -EMIEVMFGQEF-NESIPALLPHNVKVAHKTGWTGD-FFHDTGIVFPPNRKPYAISLFTHG -FPDDENQAHECMAEVSRMIYS-- ->[subseq from] Beta-lactamase n=2 Tax=Oscillospiraceae TaxID=216572 RepID=A0A1C6H963_9FIRM --------VKRQLSSVPGHIGFYYKNLVTGETD-GSRQTELFQAASVIKLPILAAILLEER -EHPGVLQERLLVRDGDKVPGCGALQHISGTQYDIESLCKLMITISDNTATNVLIRRF-GI -EFLNERFRVLGLQETKIFRFLFDTEAA-RQGKENLCQPKEIGSLLEEIYHGRCVSANASE -RMRAMLSQQQI-NHKIPSLLPPTVRVEHKTGEDE-GITNDVGILY--GREPCVLVLVSNE -TD--VPAFEQVIRTVS------- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus sp. CF112 TaxID=1144311 RepID=J2QQD1_9BACL ---DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE -QGKARIDAQLALRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK -EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGLFSRWASA -DMIAIMQKQQV-LHGLPSQLPAAWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD -VRA--EAALHTLGLLGRAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI0007072E40 ---EIVSKINQIGKKYGGRLGVSAKNFVTGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLISFDDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL -EAVNNRMKELGLNNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKVINPEISA -EIINIMKNNQD-YEMMKRYLSENVTVANKSGSIDK-MKADIGIVYAKCV-TYAVAIFCDE -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] Serine hydrolase n=2 Tax=Bacillus TaxID=1386 RepID=A0A5D4SJH5_9BACI --nQLEKRLADILRQCPGNASLAVEY--GERAI-HMNSGRKYPAASLIKIPIMMEAFFQAE -EGVLDLNEQVRIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK -KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS -KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GIEHDCAIFAS-GRDVLYAAVLIEG -LS-SPEEGNHAIRLIG------- ->[subseq from] Beta-lactamase n=2 Tax=Cyclobacterium qasimii TaxID=1350429 RepID=S7WVD1_9BACT --nQLENGIRDLMQGVEGDFGLAFRLLDSGKEL-FINEKEVFHAASTMKTPVMIELFKQSA -AGKFSLQDSILIRNESILDGSAYSYSRIGEKGSRYELMYQMIIKSSNLATNILIEEV-GA -ENVTQTMRDLGALDIQVLRGVEDLKA-FEAGLSNTTTALDMMLIMEAIAKGKVVGS---G -NMMEILSDQHF-NGLIPKYLPKTAKIAHKTGSIT-GVQHDAAIVDLVNGKRYVLVILSKN -LK-DEEVGKESIAKISQLIYTY- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus indicus TaxID=223556 RepID=A0A2D0A750_9DEIO --------------GFAGTVGLWVGTPDGEALA-SLNGDRVFPAASTIKVPLLVMALQDAQ -RGDLRLEDRVVLQAADRVPGAGVLHELGAGLLSWQDVLTLMIIVSDNTATNLTIGRL-GV -EAVNRWLGAHGLSGTRLVGKLQQRNEAQRRGERNATTAADQARLLRLLLAGDLLDPPHTA -LAVSILERQQY-RDLIGRGVPADYRVASKSGELT-GVHHDVGVIFTP--RPLVVALLSEG -GRREHPENRDVTALAA------- ->[subseq from] Beta-lactamase n=1 Tax=Saprospira grandis (strain Lewin) TaxID=984262 RepID=H6L7V4_SAPGL --eALKDSLRTICQNPKGQMGIYVYDAQLDKSF-SIAGDTLFPLASVYKLPIVASLLAAQE -AGKLSLFDSIRLNLEDRRHSGCFMDWDTTGKPKIEDLALYMMRYSDNCATDALLRQLGGP -EFVQAQLKSWMVSDININRYLIEIFIKFLWDRRDQGSPKAFVQLLKGLDQEHWLNANSSQ -WLRDCLLSCRTGRYFLPEVLPPNRQVAHKTGSLP-GIYNDAGWIEREAGRPIYYAVFLKN -AFDKPKKERARIAAAMK------ ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea maritima TaxID=683260 RepID=A0A1G9AKY9_9ACTN -------DFERIFRQAGVTGWLHATDIDAGREV-GHGADEPLPTASMFKVPLLVALCRQAD -AGLLDLSCRVTVTDADRAPGSTGLSAMRDDVISLRDLAYSMISVSDNTSADQLLSRV-GY -AAIGAVLESFGLAVTRVVQSAGEMLAALDPARANRSTPREMTTLFGLIWRDEAASAESCA -WMRTLFNAQVW-PHRLASGFPDDVSVSGKTGTLPT-LRCESGVVEYPDGGRYAVSVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5K945_9BACT ---TLRNELEKIAGESKANISVAVLDLESGFRF-SLAGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDPLHVRNRFLSAASPFRYRAIGRTVKILALAEGMIAASSNLATNLLLDFV-GV -EYARDVLRDAQISGVELRRGVQDENA-HEKGIDNEVTADGLLTLLCA-VRGDFLKQQSRE -EIIRILLAQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDAGIVYLPEREPYIVVILTEF -DA-EKDGRYQTLVGISNLIYR-- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. ND2010 TaxID=1410618 RepID=UPI0009DDA998 ---QLESSLRELMDKDSAKYQVYVFLPQWDEPL--IMGEEPQSSASIIKIFILGTAYELAE -RGQLNLNQQVTVHQADMVGGAGVINGRSGEPYTVRNLLELMITESDNTATNVLMDTI-GI -ERIQRFMKVHGFQNSVLQRKMMDFE-ALRAGRDNFTTAGDVGKFFRLLREHKLVSEAADS -EMISILFGQTD-RECFPQALP-DARIAHKTGELS-GVYHDAGIVYEAND-SYVLCIMSTD -SRGR-GNTLSTMRDMAKTV---- ->[subseq from] Beta-lactamase n=1 Tax=Flavisolibacter tropicus TaxID=1492898 RepID=A0A172TXN2_9BACT --kKLQQQLEVLVKDFKGDIGVYVKDLHSNKVV-NINADTVFPTASMVKVPILVGVMDKIN -RGELQYHQPLTYRDSLLYEGEDILGSFKQDEIQLSKVMMLMLTTSDNTASLWLQSLAGKG -TRINEILDSMGFVNTRVNSRTPGREANRSQYGWGQSSPKEMASLFEKIYKGEVISNAASD -KMLRLLNRNYY-DEVAISQLPPNALVYSKNGAVNQ-TRNETLLVKG-NKAEYVFCIMSKN -NQNNENEAWVLTRKISQLLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Microbispora triticiradicis TaxID=2200763 RepID=A0A372PGJ2_9ACTN --------LERVFRNAGVTGWLHAVDVDGGREV-GLRAAEPVVLASVFKLPLLLELHRQAE -RGLLDLAGLVRVPAEGRTRGTGLAAMLDDATLSLRDLAYLMMTVSDNAAADVLLARV-GR -EAVNTLLDGLGLTETRVVHDCRDMLTALRPERSNRSTPREMTRLLAMIWRDEAAGAASCA -AVRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LSQNQPRADAAIGAAARIAIDQ- ->[subseq from] Serine hydrolase n=2 Tax=Microbispora TaxID=2005 RepID=A0A5D0P3J4_9ACTN --------LERVFRNAGVTGWLHAVDVDGGREV-GLRAAEPVVLASVFKLPLLLELHRQAE -RGLLDLAGLVRVPAEGRTRGTGLAAMLDDATLSLRDLAYLMMTVSDNAAADVLLARV-GR -EAVNTLLDGLGLTETRVVHDCRDMLTALHPERSNRSTPREMTRLLAMIWRDEAAGAASCA -AVRRLMALQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LSQNQPRADAAIGAAARIAIDQ- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium mizutaii TaxID=1010 RepID=A0A239XUU8_9SPHI --kKLTEKINQAIAGFQGDIGIYVKHLKHNKIV-NINADSTFPTASVVKVPILVGVFQKIN -DGELRLDQEFLYRDSRAYGGSGLMQFFKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG -QSINPILDQLGLPNTKVNSRTPGREEIWKKYGWGQTTPREMATLYEMIRNGKVVSPAHSD -KMYRFLKNQFY-NERALSQFPAQVSWIGKTGSLDE-VRSEVVLVNAPHGD-FVFSFFSNN -NKTKSNEAEVLTRKIANIIWNHy ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sancti TaxID=1004 RepID=A0A1K1SWV4_9BACT --qKLEKGLHDVISGFRGDVGIYVRNLKTGHYA-EINADSIFPTASIVKVPILVGVFDKIE -KGELQYHQPLVYRDSARYGGSGIMQYFKDSATELSVLLALMMSYSDNTASLWNQALAGGG -ERINQLMEQYGMQVTRVNSRTAGRQEIWKIYGWGMTTPREMATLMLKIRNGEVVSKAASE -RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAID-ASRSEVVYVNAPHGE-YVFYVGTKN -IVTDDNEASTLIIKVSKYLWEYf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus epidermidis TaxID=1282 RepID=UPI00138E2928 ------------------------------------------------------------- -------------------------------------LIEAPMKYSDNTANNKIINEIGGI -KKIKKRLKKLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMLNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDVAFIYPKNQEPIILVIFTNK -DNKSDKPNDKLISETAKNVINKf ->[subseq from] serine hydrolase n=1 Tax=Halotalea alkalilenta TaxID=376489 RepID=UPI000694F2BD ----LAPLVAQIDQEFPGELGFYLRDLDSGEYF-SLRAQEQWYLASMVKLPVALALLDMVD -RSEASLDERMTLNASDYVDGAGETNWHGPGALRLGWLLEQMIIRSDNTATDMLIRRI-GI -ERVNARRAELVAHGFGEITTLADVRRAYYATGANSGRLDAHALLLERLQRSDALSTPSTV -HLLGVMSRVVTGEHRLKAGWPDSVGFAHKTGTQR-GRFCDGGIASRTVGTRRLVVVACTR -GSLSLADAERAMRELGAAAWR-- ->[subseq from] Uncharacterized protein n=1 Tax=Anaerosporomusa subterranea TaxID=1794912 RepID=A0A154BW80_ANASB ----LRQQIEQHLAGTPGTYSIELVLPDLGMGL-RYNP-IVLPSASLIKVFIMAEAFRRAS -IGCLDLSDSAEVTPAVRVGGAGPLEHAAYGTIKLLELIELMITESDNTATNILIRIL-GM -DSVNKLAYTIGCHNTLLGRHMMDFTAR-AAGRDNLTSPTDMNILLGRLYTNGCINPASSQ -AMLAILLRQTD-KCKLPLLLPPGTVIAHKTGELD-GIEHDSGIIYG--QTPYILTIMTEN -LPV-EEQGRQTIAELSRIVYDA- ->[subseq from] serine hydrolase n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=UPI000BE25213 ------------LQKITGKAGFYYKNLVTGEQI-TFQEDMPFQAASVIKIPILIEAFTRLE -TGSLHKTDLFTIKKQDKLPCGALTYMHDGLQVTLEDLYTLMIILSDNTATNLLIEHL-GM -DQINNTMQKLGCRQIKLNRYLFDSEKA-ALGIENYISAGDIAGLLEKMYHGELVSKEASA -EMLRILKNQRL-NGKIPFFIHGKADIAHKTGEDD-GITHDVGIVYG--KEPFIICFCGNE ---VDVPAYERLMQDISYALFK-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7QXL7_9BACT -----RAALEARIARAPARVGLYYRSLARADSI-LIGANLRFHAASTMKLPVMIQIFRDAD -TGLLGLDDSLTVHTASLVEGAFVVYALVGRNRAVRDLLERMITRSSNLATNILIERV-GA -ARAQASARSLGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLQAIATRRAASGAACD -SMLAILGRQEF-NEGIPVGLPPGTRVAHKTGWVGEVVYHDAAVVFPPDGGGYVLVVLTGG -IKED-SVAHNLVADLSRLVHD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus firmus DS1 TaxID=1307436 RepID=W7L1U8_BACFI --hTLKAEILTLASCCKGRVAVYIHT--EDGSI-EKDADAVFSSASLIKVPILLAGLLQAE -KELLQLEEEVEVTASARVGGSGVLQAMARDLIKVTDLMTLMIIVSDNTATNLIIELI-GI -EKINQLFKDLGFNNTSLSRKMMDFE-ALKSGIDNTTTARDMAYGIKALAEQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVMVAGKTGELP-GIEHDCALFTHKGK-TVCAAVLVDR -LQ-DPAAGKEVMSAIGSRI---- ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. YX9 TaxID=2282308 RepID=A0A369ILF3_9BACT ----------------------------TGEIYfSKGPAESVPSASIIKIPILVELMEQVK -AGKVDLDETYTLVTADKTGGSGVMASYPDGQMSLKEVARLMMIASDNTATNIFIRKL-GR -EKINDRMKFFGLASLQLNRVMMDTAA-VARGIDNYVTARDINALLRLIYGHKVATPALCE -QMMEFLFENRD-TVTLPRLIPKTIKIAHKTGGLTY-VRGDAGIVFAA--TPFVISVFVRG -TPE--KDAEKMIGEIGEICFNIf ->[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter barkolensis TaxID=2053187 RepID=A0A2N0VEX5_9BACT --dQLKADIENHISEEEGTFAIWFQHLQEPDRFfAINEDTLFHAASTMKTPVMIELFRRAE -AGEFDLSDSIEIENKSIVDGSEFQERRVGEMATLYDLNHAMITYSSNLTTNLLIRLV-GA -EETTETMRDLGAESIQVLRGVEDLKA-FDQGLSNRTTAKDLGIIYEHIANGTAVSPEMDS -VMVEVLKDQYY-QDVLPEYLPDDVVAANKTGFIT-GVRHDSGIFYLPDGQSYILIFLSKN -LP-DEDRGRDVGREISKKIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Salinicola sp. TaxID=1978524 RepID=A0A2D8NXX2_9GAMM --------------TVAGEIGVHVRRLDDGERV-GWRDAERWYWASLVKVPVAVELLDRIS -SDGVDLDDTMTLHASDYVDGAGATNWAAPDTIPLRTLLERMLIDSDNTATDMLMRRV-GV -EAVNRRARSLMDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIDKGEALPAAATA -TLLSIMQRADTGHRRLSAGFQRQWPFAQKTGTQY-ARFCDAGILDPGTPGAVVVVSCLRG -A-PSRREAERTFQAIGRAV---- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus aquatilis TaxID=519440 RepID=UPI00037A0CB9 ------------ERGFAGVLGVRVCDEAGQELF-SLKADRVFPAASTIKIPLLVMALQAAQ -RGELILTDRVTMHAADRVPGAGVLHELSADLLTWQDVLTLMIVVSDNTATNLVIDRL-GV -QAVNAWLDTAGFASTRLVGKLAQRNEAQRRGERNRTTAHDQTELLGRLWRGDFLDSTHTD -LALSILSRQQY-RDLIGRRVPCGYRVASKSGELG-GVHHDVGVLWTP--RPLVVALLSEG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Olivibacter sp. LS-1 TaxID=2592345 RepID=A0A5C0ZPR3_9SPHI -----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE -RGKLALSDSVEVYNESIYDGSSYAYSLIGKKAALADLLLRMITQSSNLATNIVIDLV-GA -KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE -QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG -VD--EKLAQQYLAEISGVFYHY- ->[subseq from] serine hydrolase n=1 Tax=Olivibacter jilunii TaxID=985016 RepID=UPI001031BE8E -----KRKIEKVQKGNPGTFAIAFKDLSDNDTF-FYNEHQLFHAASTMKTPVLAETFRQIE -RGKLALSDSVEVYNESIYDGSSYAYSLIGKKAALADLLLRMITQSSNLATNIVIDLV-GA -KNVMKTMERLGAKEMKILRGVEDSKA-FAHGMNNMVSAYDLSLLFVQLARGEMINSRSSE -QMLDILMKQHF-RGIIPAELPADVKVANKTGSINK-VCHDSGIVFLPDGRKYVLILLSMG -VD--EKLAQQYLAEISGVFYHY- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7G2L9_9BACT ----VRERLAARVAQAPATVGLYYRSLTHPDSL-LLDANVRFHAASTMKLPVLIQVFRDAD -AGLLRLDDSLTVHVVSLVDASPFDYGRVGRPASVRDLLELMITRSSNLATNILIERV-GA -GRAQGSARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGVLLAAIAQNRAASPASCR -EMLRILEAQEF-NEGIPVGLPPGTRVAHKTGWIGEVVYHDAAVVYRSSGGSYVLVVLTGG -IKQD-SVAHNLVADLSRLVY--- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7ERK8_9BACT ------ERVAARVAQAPATVGLYYRSLTRPDSL-LLGANLRFHAASTMKLPVMIQIFRDAD -AGLLGLDDSLPVHATSLADGSPFDYRRAGKLASVRELLELMITRSSNLATNILIERV-GA -ARAQASARTLGAWSIQVLRGVEDGK-AYRARLNNTTTARDLGVLLAAIAGRRAASPAACD -SMLAILGRQEF-NEGIPAGVPSGTRVAHKTGWIGEVVYHDAAIVHPATGGSYVLVVLTGG -IKQD-SVAYNLVADLSRMVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus ficus TaxID=317577 RepID=A0A221SY04_9DEIO -------------SGFAGEVALHVTDLGGRVLC-SHQPDEAFPAASTIKVPLLVQALQEAQ -AGRLDLTGRVTLGAADRVPGSGVLHDLLPGLLAWQDVLTLMIVVSDNTATNLVIGRL-GV -DAVNAWLAAQGLSGTRLVGKLEQQNEAQRRGARNRTTARDQAALLGALVRGELLDPAHTR -LALDILERQQL-RDLIGRRVPADYRLGSKSGELR-GVHHDVGILHTP--RPLVVACLSRG -GTDPRE----------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Dolichospermum circinale AWQC310F TaxID=553470 RepID=D1FNP1_9CYAN ----------------------------------------------------------DVD -AGKIRLDEILTLEKEMIVGGSGNIQQAPGSKYTALDLATKMITISDNTATNMLIAKLGGQ -EALNGRFRSWGLTTTMIRSPLPDLQGT------NTTSPRELGNLISMVNQGNVVTMRSRD -SMLNIMSRTER-DNLLPAGLGKGANAYHKTGDIGT-MLADAGLIDVPTGKRYIAAIMVQR -PNND-PRAAKLISSISSSAYQYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_68_21 TaxID=1805084 RepID=A0A1Q7EWR3_9CHLR -------------ASFPGEAAAFACDDRGGELF-AERADEVFPAASVIKLPLVMALYADAA -RGEIDLGERVRVG--DRVDGTGVLRHMRDVEASLRDLAMLSIIVSDNTATNLLVDRF-GL -ERVNERMREWGCSESRFARKMYDFDAA-KCGKENFMTARETASLLLRLLRGGCGDRATSD -AVLAILDECQD-RTMLRRYLPYGAKVAHKTGTLDE-SRNDAAIVRG--ERPVVVAAFSRK -VS--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Thermoflavimicrobium sp. FBKL4.011 TaxID=2137476 RepID=A0A364K797_9BACL ----LETQIKKYVDSFDGKVGVAIQ-TEAG-SI-HYREHEPFLAASLIKIPIMIEAYRQVQ -AGRLDLYQLYKVPSNQRVGGSGVLFNLGEEIVSLQDLISLMIMISDNTATNFIIDQI-GI -DTVNDLASELKCDQTMLGRKLMDYTA-KKRGFENFTSAYDMVHFFKEMVEGNSLHPEYKR -LILKSLRAQQF-QSKLPGDLGEGDFIAHKTGEMTN-YEHDAGILSVGGK-VAYIAVLTSD -GP-DAFTRRTLIADIGKAVFD-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium carboxidivorans P7 TaxID=536227 RepID=C6PSK5_9CLOT ----LEELLKNSLKNSEAKYSLAVKNLRSKENC-YINTHEVVPSASIIKLFIMSEAFNKNK -MGKLNLHEIIKIDNDKKVPFSIVSLLNSVEQYSVKDLITLMIIQSDNTATNVLIDFL-GI -DNINNFIKERGFKNTVLGRKMMDFEGA-KAGKDNYTSAYDVFSFLEKLYNHNLVGEEEDK -LMIDILSHQLD-FSMMRMDMLDDLKIAHKTGDLNC-LKHDAGIVYSEKVGDYIFVMFTYE -AK-SDGYARKLICKTSEQIYDYf ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A6C9C6P9_ECOLX ------------------------------------------------------------- ------------------------------------------------------------- ------FLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudomonas indica TaxID=137658 RepID=A0A1G9IQF2_9PSED ---QLQGKILRLDQRTPGDLGVYIKHLGDGGEL-DYQAGRHWYLASAVKVPVAIATLQRVD -EGVWPLDQRLALRNEDKVDGSGGLAQDSGSEYDLKTLLEEMLQRSDSTAADMLINRV-GE -DELNRRIASMADQGTSLLRVRHELYRRYYARRLNAATLRAYGGMLEKLARGRLLSRANTD -LLLDLMGLDEYHAYRLEAGLGKDVPFAQKTGTQFE-RACHMGIIDPKSEQAIVIAACVED -AGQE--QAAQTLEM--------- ->[subseq from] Beta-lactamase class A n=1 Tax=Natronincola peptidivorans TaxID=426128 RepID=A0A1I0FZL7_9CLOT ---RLQERIQQHIDKINGTVGIYIKNLNNNKTI-IINGDERFHSASIIKIPILWEGLRQVE -IGMKTLEETIALKKEDKVGGCGVLTLLQEGLLTLEDLLHLMVDISDNTATNMLIDHL-GR -DNINATLQSMGMKNTYLARKLMMVIPE----TYNYTTPKDIGSMLERFVIGNGLNNVYAE -KGMEILSKQQL-ND---------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Salinicola acroporae TaxID=1541440 RepID=UPI0013A65FF4 ----------------TGEIGVHVRRLDDGERV-GWRDAERWYWASLVKVPVAVELLNRIS -RDGADLDDTMTLHASDYVDGAGATNWAAPGTISLRTLLERMLIDSDNTATDMLMRRV-GL -EAVNRRARSLMDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIGKGEALPAAATA -TLLSIMQRADTGHRRLSAGFQRQWPFAQKTGTQY-ARFCDAGILAPGTPGAVVVVSCLRG -A-PSRREADRTFQAIGRAV---- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U8L5_9BACT ----------AIRDRHEERLGIAFYDAETTLQW-SYNADAMFHAASTMKLAVLLAVFRQHT -RGELALEEPVHVRNKFLSIRKPYMFERLGRTMSVEQLAYHMITSSSNFATNLLVDVV-GV -PVIQTALDELKIEGIKVLRGVEDQ-AAFEAGLNNEVTANGLLKLLRLVEEGKAYGEEASA -RMREILLDQRF-KSGIPAGLPQAARVAHKSGNIST-VHHDAGIVYLEGRKPYVLVILTQF -PSE--TGARTAVADVSRDIYE-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3D1V647_9CHLR -----------------------------GNRW-SHNGQRQFKAASTVKIPLMIEIYRQID -RGERSLDERHVLSAIEKAAGSGVLLHHDGIELTLDDLIYLMISISDNTATNMLIDLA-GM -DAVNATMLELGMSMSTLARKMKGRP-AIEGEQENLATPDDYVAIVDAIFGDRATSTAARE -AMVTMLSRQQN-ARRIARYLPADLRWGSKTGSIA-GVTNDVGFVETPVGR-MILAVFCEG -FP-DQHDGEYAIGELSRAALH-- ->[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. P3-122 TaxID=2024223 RepID=A0A255T0W8_9BACT -----------------------------GDLYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVRLTEKEMKKNPHRATGNSATPKEMARLLEWFYLHRN-DNKNLS -FIWNTMADCNTGKQRIAAVLPKGGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQN -SKEEKEVAE-------------- ->[subseq from] serine hydrolase n=1 Tax=Pseudomonas indica TaxID=137658 RepID=UPI000BAB35AB ------------------------------------------------------------- -----------------------------------------------------------GR -ERVRALARTLDVDPSELRSLEQAYQ-RYYARRLNAATLRAYGGMLEKLARGRLLSRANTD -LLLDLMGLDEYHAYRLEAGLGKDVPFAQKTGTQFE-RACHIGIIDPKSEQAIVIAACVED -AGQE--QAAQTLEM--------- ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9FY17_9CHLR --eQLENTLKDKITSFDGVAGLAVKSLTGGKNI-SINGDEVFPTASTIKIHVLAKLFSLQE -EGEIDLSARIRFTRNMYGAGSGVIHFLENDPFTVLDVAILMMLASDNTATNTCIDIA-GM -EGVNDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELITMMDHLHNQKP-SPKVSA -QVLRIMSKPKS--AYLNKAIGSTVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF -SMVDSIAQEGFLIDLARTIH--- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_20CM_3_53_8 TaxID=1803431 RepID=A0A1Q7YCY4_9BACT ----LDARVRAEISSFKGHVHLFAKNLDSGETY-ELNADDVVPTASTIKVAIMVEAFARVS -EGRSKWMDEILLTPQAKKVGSGVLQNLSDNLLTLRDVVTLMIIVSDNAAANLVLDVV-TP -DAVNARMDSLGLKQTRVLRKIGAGNTFITRYGTGMTTPREMLELLEMIERGQIINAAASR -EMIDIMKRQQL-HYGIGRNLQ-GIEIASKSGALDH-LRSDVGIIYTRRG-RIAMAVTCND -IPSYDNPGDLLIARLSQILID-- ->[subseq from] serine hydrolase n=1 Tax=Luteimonas abyssi TaxID=1247514 RepID=UPI0009E8E54B ------------------------------------------------------------- -----------------------------------------------------------GE -PRLVALAERLGVSRTDLDANLDEVFARYYDTGRNAATLEAFAVLLERLVTGDLLSPESTA -IVLGHMRSISTGDRRIQAGLPRGADFAQKTGTQF-ARACNVGVIDADRGDGAVIVAACAE -DYDDIAEAEQAFEALGRAL---- ->[subseq from] serine hydrolase n=1 Tax=Gelidibacter japonicus TaxID=1962232 RepID=UPI0013D74D9C --kTLEKGLQDLAKDFEGDVGIYVYNLKTNQEA-GVNADTIFPTASVVKVPILIEVFKQIK -AGKLHLKDTLVYDAKRKYGGSGLMQFYKDSTTDLRTLASLMITMSDNTTSLWCQELVGGG -EAINETMADLGLAHTRVNSRTEGRTKDWEAYGWGQTTPREMASLLIKMRNRTLVDAASSD -EMYRIMSNSFYTDYSL-SQIPPYVQTAAKQGMVNK-SRSEVVMVNAPSGD-YVFYIATKN -NTDEDNKAWQLQRLISAY----- ->[subseq from] Beta-lactamase class A n=2 Tax=Sphingobacterium nematocida TaxID=1513896 RepID=A0A1T5F351_9SPHI --rALEHKIKKEINGFQGDVGIYVHQLKTNKIV-SINADTVFPTASIVKVPILVGVFQKIA -QGELKLNQAFKYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELSGGG -AMINPLMDQLGLEQTKVNSRTPGREKIWEEYGWGQTTPREMAKLFTLIRNGQVVDARHSD -KMYRYLKNQFY-NGRSLSQLPPEVNAIAKTGSVDQ-ARGEVILVNAPSGD-YVFCILTKN -NKTDDNEAEELTRKLSSIIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2W0BIW7_9BACT --sALQSKIEALAAQHHGKLTLYASNLKTGATV-AVDAEKAVPTASVIKLPILVDAMEQVK -AGKHKLSENITLQKDDIVQGSGILQFFDTPLITLKDALTFMIVESDNTATNLVIDQI-GI -KNVNDHIASMGLKDTYLYKKVFKMPAEQKKFGLGKTSAMEMAKVMESIVRCDLKDQVLCD -DMLYMLRNQQY-RNLVPHYIETSSLIANKTGSLDE-VRNDVAVVYSKNG-PIVISAFTYD -NQNNDNAAELLVAHVAKLIMEAw ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. 1.A.5 TaxID=2044604 RepID=UPI000C0C0497 --kSLERKINQAIEGFQGDIGVYVKHLKKNKEV-AIHADSIFPTASIVKVPLLVGVFQKIK -NGELRLDQKFLYRDSRAYGGSGLMQFFKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG -QTINPILDELGLKNTKVNSRTPGREEIWKKYGWGQTTPREMSKLFELIREGKVVSPEHSD -KMYRFLKNQFY-NERSLSQFPAIINTISKTGSLDD-ARGEIVLVNAPHGD-FVFTILTKN -NKTKENEAENLTRKIANIIWNHy ->[subseq from] serine hydrolase n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=UPI000BA919BF ----LAETVDAIVAQYGATVAVAVRS--PSRRF-DRLADRTFHAASTMKVGVMIEAFRQVQ -AGRRAWDDPVRVENRSIVDGTEYQYALQGRDVTFRTLTERAITTSSNLATNLLIGLV-TA -ESVQATMDRLGAPGLRVLRGVEDLKA-FEAGLSNATTADALATVLEAIRDGRAVSPAADA -EMVDILDDQAF-NEMIPAGLPAGTRVAHKTGWITE-IHHDAAIVYPEGAEPYVLVILTEG -LA-DHDESARLGAEVARAVH--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536Q7A3_9CHLR ---------------FPGEAAAFACD-DRGRELlAEQADELFPSASVIKLPLVMALYADAA -RGEIDLEERVRVGE--RVDGSGVLRHMRDVELSLRDLAMLSIIVSDNTATNLLVDRF-GL -DRVNERMREWGCSESRFARKMYDFDAA-RCGKENLMTARETASLLLRLLRGDCGDRATSD -AVLAILGECQD-RTMLRRYLPYGAKLAHKTGTLDE-SRNDAAIVRG--ERPVVVAAFSRK -LTDT------------------- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus ficus TaxID=317577 RepID=UPI0006864017 -------------SGFAGEVALHVTDIRGRVLC-SHQPDEVFPAASTIKVPLLVQALQEAQ -AGRLDLTGRVTLGAADRVPGSGVLHDLLPGLLAWQDVLTLMIVVSDNTATNLVIGRL-GV -DAVNAWLAAQGLSGTRLVGKLEQQNEAQRRGERNRTTARDQAALLGALVRGELLDPAHTR -LALDILERQQL-RDLIGRRVPADYRLGSKSGELR-GVHHDVGILHTP--RPLVVACLSRG -GTDPRE----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1G7RKJ5_SELRU ---QLEASLRQLMDKDSAKYQVYVFFPQWDEPL--VMGDGPQSSASIIKIFILGTAYELAE -RGQLELNQQVTVHQSDMVGGAGVINGRSGEPYTVRKLLELMITESDNTATNVLMDTI-GI -ERIHRFMREHGFQDSVLQRKMMDFE-ALRAGRDNFTTAADVGKFFRVLREHKLVSETADS -EMIAILFGQTD-TECFPQALP-QARIAHKTGELS-GVYHDAGIVYEAND-SYVLCILSTD -SRGR------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=A0A243RL42_9ACTN ------------FRAAGVTGFLHAVDLDTGAEV-AHDADEPVVMASVFKLALLVEFFRQAD -AGLLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLAGRV-GL -SAVNTMLAAEGLDGTWVEHDCRGLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3D1TZC7_9CHLR ------------------------------------NADELYLLASVFKVPILLEALAQVD -EGRQGLDERFELRRDDQLPTSIILEHLDPGLLTLRDLLTAMITVSDNTATDMVLAIV-GL -ENVMARLTSWGLRDIAIHMSVQGLFDAQRTLENNVSSPRAIGELLERLVRGELLSRESTG -VALDIMLRQQL-NQRLPRFLPANVPIAHKTGIFYS-SRNDAGILYLPDGGRVVVVSFS-- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6KPE4_9BACT -----------------------------DRIL-LRNADRIFPTASSIKIAILLELYRQDQ -KERAKLDDLYTFDPKDLVEDSRIMAGLTPGVVTNRDLAQFMIAVSDNAATNILIDRV-GK -DNVNTMLRGLGFSKTLLRRKMMDTAAARRG-DENVATPQEMARLLEAIYKEMVLNKQATA -ELIKQLSTKKE--SYIPRYLSENIQVANKPGELE-GVRNDCGIVFVQNR-PFIVSVMTAY -DR-DEKAAERAISDVALHAYYYf ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=UPI0013FD10BE ------------FRAAGVTGFLHAVDLDTGAEV-AHDADEPVVMASVFKLALLVEFFRQAD -AGLLDVTERVTVMADRHTPPTGVSAMADDVTMSLRDLAYLMIAVSDNTAADTLAGRV-GL -SAVNTMLAAEGLDGTWVEHDCRGLFAALDPARTSRSTPRDMTRLLGMVWRDEAASAASCA -SMRRLLGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia speluncae TaxID=419477 RepID=UPI00082B25FC -----AERIHAVFADAGCTGRLHARRCDGGAEV-SIGGTERVVTASVYKLPLLLAYCRAVD -AGRIDPLERLTLTPAECTPPTGISALHDPVTLSRRDLATSMMTVSDNAAADLLLGEI-GL -PRVHDLLDSLGLTRTRLVGGTADIQRAYDPAYTSATTPEEMTRLLSALWRGEVVSPQQTD -FARAVMRRQVW-PHRIAAGFPRAVSVAGKTGTIGI-IRNEVAVVEFPGEYSVAVAVFTRA -ARADLPAVDAAIAEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Aneurinibacillus sp. XH2 TaxID=1450761 RepID=A0A109QEB4_9BACL --------------QVDGKVSVAIE-TDEGHIL--INANDPLPSASLIKIPIMIAAYRQAQ -EGKLNLFSEYSFLPEDRVGGMGVLSHLSPELLTLKDLISLMIMISDNTATNMVIRNV-GM -DTVNQLAADLNCGQTVLVRMMMDH-EAVKRGKDNMTSASDIVRFLKEIVEGSILNEENKK -AVYDTLLNQQF-HTKLPAGFSLHATLAHKTGELP-GTEHDAGIFCFNGK-YAYVAVLTTE -LS-DNASGQRVIAQVGKLVFHY- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. OG2 TaxID=1979526 RepID=A0A231WA86_9BACI --nQLEKRLADILRQCPGNASLAVEY--GERAI-HMNSGRKYPAASLIKIPIMMEAFFQAE -EGVLDLNEQVRIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK -KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS -KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GLEHDCAIFAS-GRDVLYAAVLIEG -LS-SPEEGNHAIRLIG------- ->[subseq from] serine hydrolase n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI001411F9BB ---------------------------------fSKGPAEPVPSASIIKIPILVELMEQVK -AGKVDLNKTYTLVATDKTGGAGVMASYADGQMSLKEVARLMMIASDNTATNIFIRTL-GR -EKINDRMKLLGLASLQLNRVMMDTAA-VARGIDNYVTARDINALLRLIYSHKVATPALCE -QMMEFLFENRD-TVTLPRLIPKTIKIAHKTGGLTY-VRGDAGIVFAA--TPFVISVFVRG -TPE--KDAEKIIGEIGEICFKIf ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga ginsengisoli TaxID=363837 RepID=A0A2P8GE06_9BACT --rKLEKGLQELIKGFNGDIGIYVRNLKTGRYV-GIHEDTIFPTASIVKIPILVGVFDKIE -KGELTYHQPLIYRDSIKYGGSGLMQFFKDSTTDLSVLLALMMSYSDNTSSLWNQALAGGG -QRINELMAQYGLSVTRVNSRTPGREDIRNVYGWGMTTPREMAELVVKIRQGEIVSKAASA -RMYRLMTHGYY-DETGLSQIPPYVQAAHKTGSVD-ASRSEVILVNAPHGD-YVFYVGTKN -NKTDENEAENLIRKISKYLWEYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8RK15_9BACT ----LDRRVRDEAAKFEGTVSLYAKNLDTGAEY-SFGGDERVRTASTIKIAVMIEAYARVA -EGRAKWTDELVLTKEKKVSGSGILQEFSDGLLTLRDAVTLMMVLSDNTATNLVIDVL-GA -DAVNARMQSLGMTETRLMRKIGGGGDSEEGKKEGRTTPHEMVTLLEKLERGEIVSPSVSK -EMIDLMKREQGTDGIWRALWK--TPKATKSGALD-ALRSNIGIIYHTRG-RIALAVTCDD -MPEPDNPAYHLMSRLSEIVI--- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E5GXI5_9BACT --tSLEETIEKQLQSLDAETSFYAKHLPSGREI-SIRADQPMNPLSVIKIPMMVLAFQDTE -NGQFDLDQRYRIRAEDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNNL-TM -ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD -EMVNILRRQFY-NSRIPRFLRGKATVGHKTGDWAPHAGNDVGILYYPGG-PSIMAIFTNQ -NKGDFVELEATIGKIAEDIVNHw ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3B8VC05_9BACT --dSLHAAIHELIARTQGTIGIAYINLQDPSDTlFINADEMFHAASTMKTPVLIEAYKQAA -AGGLSIKDSMLVHNSSIADGSSFSEMHARIGVPIRDILYDMTINSGNLSTNLIIDKV-DA -KKVTQTMRDLGASKIEVLRGVEDMKA-FDAGLSNRTTARDLAIIFQHIANGTAVSQEASN -DMIDILLDQQF-KEMIPAKLPKSVKVAHKTGWIT-GVVHDSGIVILEDGRQYVLVILSKN -LEEN-NLGTEIGADISKLIFEWf ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A141REZ2_9BACT ------------------------------------------------------------- ------------------------------------------------------------- ---MTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] serine hydrolase n=1 Tax=Veillonella magna TaxID=464322 RepID=UPI0009FC4DA6 -heDAKKAIGQILGDEVSKYGIYAFYP-TADTVpLIIQSRPMRSASMIKVFIMGKAMQEVE -RGRLSLDEMITLKANDKVGGAGIIAGWADGTIPVRELLRLMITESDNTATNLMIDRL-GM -EAINEYIRQEGYGETKLQRKMMDTAAA-EAGRENITSPADLGHFFTRMWKGEGMTAGTRE -QMLTWLYEQTD-TECLPQAFPQG-KIAHKTGELV-GLYDDGGIVVREG-TPLVICIMNDD -ID-SRGGAIRDMQKIAR------ ->[subseq from] Beta-lactamase class A n=2 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=A0A0P1LV98_9BACT ---EIVSKINQIGKKYGGRLGVSAKNFITGETI-QINADSLFPTASVIKVPILVELFYKFE -EGKLKKDTLISFDDSLKYGGSGVLQYFYDGALKLIDVAVLMIILSDNTATNLVLDCFADL -EAVNNRMKELGLNNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKVINPEISA -EIINIMKNNQD-YEMMKRYLSENVTVANKSGSIDK-MKADIGIVYAKCV-TYAVAIFCDE -LSAVDNKGHLAVAEISKLIFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358IGK6_9BACT ------------------------------------------------------------- ----------------------------PGVQLSIHNLLELMLQISDNIATDILFEIAGGA -EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMARLLRKIWDQEILSEKSSS -LLIDIMYRCQTGEARLKGALPPGTQVAHKTGTIGE-TTNDVGIIDLPDGGHVITVVYIKE -SKPDNPAMEPVIANIARAIHDYf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AMD4_9CHLR ------------LDRTRGVTGVVVREVGGATLF-SQRPDEVFPAASVIKIPLVMALYAEAA -DGRLSLEERMPVGA--IVGGTGILGDLRDVRVSLRDLAMLAIALSDNTATNRLIDRL-GV -ARVDERMAEWGCVRTKLARGMFDWDAQ-RRGLENVAAPSEMAALLERLVCGELVDRATSD -AVVAVLERCQD-DAMLRRYLAKGGRVANKTGTLA-ATRNDAAILFGPSRT-IVVAAFMRE -VA--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=A0A2E3QZG7_9BACT ----LAETVDAIVAQHGATVAVAVRS--PSRRF-DRLADRSFHAASTMKVGVMIEAFRQVQ -AGRRAWDDPVRVENRSIVDGTEYQYALQGRDVTFRTLTERAITTSSNLATNLLIGLV-TA -DSVQATMDRLGAPGLRVLRGVEDLKA-FEAGLSNATTADALATVLEAIRDGRAVSPAADA -EMVDILDDQAF-NEMIPAGLPAGTRVAHKTGWITE-IHHDAAIVYPDGAEPYVLVVLTEG -LA-DHDESARLGAEVARAVH--- ->[subseq from] Uncharacterized protein n=1 Tax=Prevotella sp. P5-92 TaxID=2024222 RepID=A0A255SWS2_9BACT ----------------------------NGELYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVNKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNIS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK -SKEEKGVA--------------- ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=A0A292QYB0_9BACT ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMLLTNYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium CG12_big_fil_rev_8_21_14_0_65_60_17 TaxID=1973924 RepID=A0A2H0JXZ9_9BACT ---------------------------GTAAEF-HMNGNRLFHAASTMKLPVMIEVFRRAE -RGDFAMDDTIVLRNSSIVDGEPFSYDKLGQPMSLADLTYNMIIVSSNLATNLLIDEL-TA -DSVQATSERLGTTHMKTLRGVEDLKA-FERGMNNQATSHDLALLLTRLMNGTAVNARSDA -AMRQILLDQKF-NEIIPAGLPSDVRVAHKTGQITR-INHDAAIVYPPGDDPYVLVILMEG -IS-DHDASARLGAELARAIH--- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. NW-56 TaxID=2080419 RepID=UPI000CF4DE97 -------------RGYGGEVGLLIHDLAGRELF-SLNADRAFPAASTIKVPLLVQALEEAQ -AGRLDLSARVAMTAQDRVPGSGVLHELDEGLLTWRDVLTLMTVVSDNTATNLLIGQL-GV -ERVNAWLDKRGLTSTRLVGPLPRQTEAQRRGERNRTAARDQVALLGQLARAELLDPPHTE -LALSILARQQF-RDLLGRYVPRDYRVASKSGELR-GVHHDVGVLFTP--RPLVVALLSQG -GTDPRE----------------- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium paucimobilis HER1398 TaxID=1346330 RepID=U2IY46_9SPHI ---KLEQKLKQEITHFQGDIGIYVHQLKSNKIV-AINADTIFPTASIVKVPILAGVFQKIA -QGELKLEQPFQYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELAGGG -AQINPLMDQLGLTHTKVNSKTKGREKIWEEYGWGQTTPREMAKLFTLIRNGAVIDPRHSD -KMYRYLKNQFY-NERSLSQIPAWVSTIAKTGSVDR-ARGEVVLVNAPGGD-YVFCILTKN -NQTDKNEAEELTRRLSSIIWNHf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura atramentaria TaxID=1990 RepID=UPI0009FDF764 -------AIEDAFRAAGVTGWLCALDIDGGRGV-AVRGDEPVVLASVFKVPLLVAFFRRAA -AGLLDPAEAVTLRPADRSDGPTGTSVLLDDVMSLRDLAAMMITVSDNAAGDVLYARV-GR -DEVNRAMADLGLTATHIASDGRELAAALDPLRTSRSTPREMAALLAAVWRDEAAPPAECA -LMRRMLGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRA -LRAVLPQADAVIGAAARLAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. S165 TaxID=2135462 RepID=A0A317LYG9_9BACT --rKLEKGLRELIKGFNGDIGIYVKNLKTGRYA-GINEDTIFPTASIVKVPILVGVFDKIE -KGELKYHQPLIYRDSIKYGGSGIMQFFKDSTTELSVLLALMMSYSDNTSSLWNQALAGGG -QRINELMEQYGFSVTRVNSRTPGRAEIRNIYGWGMTTPHEMADLVAKIRKGEIISKAASE -RMYRLMTHGYY-DETGLSQIPPFVQAAHKTGSVD-ASRSEVLLVNAPHGD-YVFYVGTKN -NKTDENEAENLIRKISKYLWEYy ->[subseq from] serine hydrolase n=1 Tax=Nocardia thailandica TaxID=257275 RepID=UPI0002DE1B33 ------------------------------GEV-DLGGRERVVTASVYKLLVFTAYCRLVD -QGALDPRARLTVDPARCTPPTGLAALRDPVTLSLRDLAASMMTVSDNAAADILLDLV-GP -AAVAALAAEQGLTATRVVGGMAQVHEAYDPAYASATTPEEMTRFLRALWTGAVLSPAGTA -TVREVMGAQVW-PHRIAAGFPPGVRVAGKTGTIG-AIRNEVAVVEFPGEHPVAVAVFTRA -ARPQLAVVDAAIAETARLAVT-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 47-3 TaxID=2486013 RepID=UPI0013DE4AF9 ---QLQQIAQKTVLAVPGTNSVYVKKFATAGTY--VANNRPQRAASVIKLFIMATAFQQIA -AGKFTLNEPYTLTAADKVGGSGVMQGSVGTKVTLAQVMQYMMDDSDNVASNIMLAKVGGL -AAVNAECRHIGTKDTIMARKLMDMQA-LAAGHDNMTSVADLGKLLSKLYQHRLVSPAADT -QMLALLAQNKN-HTKLPAQLT-GAKVYNKTGEFDYGVQNDAAIIANDHGA-FVAVVLAQG -GAQQAQ----------------- ->[subseq from] Putative beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=D1PHG0_9BACT ----------------------------NGDLYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRTIENSATPKEMARLLEWFYLHRD-DNKNLS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK -SKEEKEVAEI------------- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520EH61_RHOSO ------------------------------------------------------------- -----------------------------------------------------------GT -AALTDFARSLGDTEFRLDRTEPELNTAIPDDPRDTTTPNSMAAGYRTLLDGDVLAQASRQ -QLLDWMAGNQTSTARFRAGIPPQWTSADKTGTGSYGVSNDAGLVLGPEGQKILLVVLSAT -TSEDSPAMNALVADTTRTVVEQ- ->[subseq from] Beta lactamase n=1 Tax=Nocardia cyriacigeorgica (strain GUH-2) TaxID=1127134 RepID=H6R1V2_NOCCG ---EVTDRIRAVFADAGCTGWLHARRCGSPAEI-SVDAHDRVVIASVYKLVLLVAFCRRVD -AGLIDPRAPLTVHPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEELLTELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLDLIWAGGVLSPEQTG -FVRAVMGKQVW-PHRIASAFPRGVGVAGKTGTIGV-IRNEVAVVEFPDEYPVAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) TaxID=546271 RepID=C9LUU8_SELS3 ---ALVDEVRRLAARGGAKFTVYLADPDDGNAP-LIRDADEMRAASMIKVFILACAMEKVK -AGELHLDDVLRLEEVDKVGGAGVITGYRAGTFSVEELLRQMIAESDNTATNMMIDRL-GM -TEINGYMRAHGYDASRLQRKMMDD-AAVKEGRENITSAKDLGTFFLRLYRSECVGEPYDG -KMRDMLFAQTD-RECFPQALP-GARIAHKTGELDR-LYADGGILYGEDGRAVILVILADD -IE-RRGRAIEMMREIARRVMQ-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces alboflavus TaxID=67267 RepID=A0A1Z1WGE4_9ACTN --------LQDAFAEAGVTGRLHAVDIDSGAEV-GVGADQPVVTASVHKLCVLVTLHEQAA -AGRVDLTEQIECPPEDRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAELLLERV-GL -DAVNATTARLGLTRTRAVHSFREMFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ARATLPSADAVIGTAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A3D0P216_9BACT ---SLDERIKAEIGDFKGKVWIYAKNLDTGKEY-GMRADEQVRTASTIKLPIMLEVYRQVA -EGKIAWTDPIEITKAVKVGGSGILFEFTDGTIDVKTAMTLMIVQSDNTATNVILDKV-SS -NSVNDFMAKLGLNDTLSLRKIGGGGDAKAWDEPGRSSPRDMVKLLEMLEKGEVVSKEASA -EMIAILRRQQY-KDGIGRNSLDTVPVASKSGSLDR-LRSDVGIVYTRRG-RIAMAITVDD -M---------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A349K9F1_9CHLR --kQLETTLKDKITTFDGVAGLSVKSLTSGKSI-SINGDEVFPTASTIKIHVLAKLFSLQE -EGEIDLSQRIRFTQNMYGSGSGVIHFLENDPFTILDVAILMMLASDNTATNTCIDVA-GM -EGINDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELILMMDLLHNEKP-TPKVSA -QVLRIMSKPKS--AYLNKAVGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF -SMVDSVAQEGFLIDLARNI---- ->[subseq from] Uncharacterized protein n=1 Tax=Aneurinibacillus migulanus TaxID=47500 RepID=A0A0K2WIW9_ANEMI --kQLDAYISRLIEETCGTWGIVIEDLDEDKRW-EWNTQESFLAESIIKVPVMAAAFAAVE -KKQFHLHDYVCLKKEDMVGGTGVLQHLTPGVLTIYDLITLMIIQSDNTATNIVIDLV-GM -ECIQETLEELGMEKSQFHRKMMIYPVH--IESKNVITADDASTLLKKLATGTFRSRHACE -QMIQILKKQQI-CNGLSSMLPPGWEFASKSGWDDD-RQHDIGILYTGQR-TFTISALSKG -GN--SLQAKQVLGKIGLVVFEY- ->[subseq from] Uncharacterized protein n=1 Tax=Halomonas sp. BC04 TaxID=1403540 RepID=W7Q0U5_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- --RLRWFARRLGIERDSLQPSLEEAFRAYYATGLNGGRLDAFAELLVALGEGRALGTEATA -ELLAILSRTSSGERRLKAGLGRDIRFAHKTGTQHR-RACDAGIASHGEGPQRAVVVACTR -GVLDVARSEQMLAAVGRAIYE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. ZZV12-4809 TaxID=2575830 RepID=UPI001357E0B1 -----KAGTLKLASSCEGRVALYIHT-E-DGFI-EKSADAVFSSASLIKVPILLAGLLQAE -KGLLQLEDEVEVTASARVGGSGVLQAMARDLIKVTDLLTLMIIVSDNTATNLIIELL-GM -EKTNQLIKTLGFNNTSLNRKMMDFA-ALKKGTDNTTTARDMAYGIKALAEQKLLSGKYTE -KALYILENQQFKNKLANTIETEKIKVASKTGELP-GIEHDCAIFTHKGK-TVYAAVLVDR -LE-NQSTGKKVLSAIGNRISQ-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces alboflavus TaxID=67267 RepID=UPI000B429EA6 --------LQDAFAEAGVTGRLHAVDIDSGAEV-GVGADQPVVTASVHKLCVLVTLHEQAA -AGRVDLTEQIECPPEDRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAELLLERV-GL -DAVNATTARLGLTRTRAVHSFREMFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ARATLPSADAVIGTAARIAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium yanglingense TaxID=1437280 RepID=A0A4R6WCR9_9SPHI --qKLEQKIKKEIAGFRGDIGIYVHQLKSNKFV-AINADTVFPTASIVKVPILAGVFQKIA -QGELKLEQPFTYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELAGGG -AQINPLMDQLGLTHTKVNSRTAGREKIWEEYGWGQTTPQEMAKLFTLIRNGAVVDARHSD -KMYRYLKNQFY-NGRSLSQLPAWVNTIAKTGSVDR-ARGEVVLVNAPSGD-YVFCILTKN -NQTDANEAEELTRKLSSIIWNHf ->[subseq from] Penicillin-binding protein transpeptidase n=1 Tax=Acinetobacter sp. CAG:196 TaxID=1262690 RepID=R5SXM2_9GAMM ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Gastranaerophilales bacterium TaxID=2137880 RepID=UPI00101BAD31 ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium gobiense TaxID=1382456 RepID=A0A2S9JSF2_9SPHI ---KLERMLQKEIKDFQGDVGIFVQHFKKNKTV-AIHADTLFPTASVVKVPILVGVFDKIE -RGQLKLSDAHIYDADRIYGGSGLMQFYKDSSTNLSTMVSLMLTYSDNVTSIWCQELAGGG -TAINQLMDKLGLPNTKVNSRTAGRQEIWEKYGWGQTTPREIVQLMTMIREGKAITPRLSD -KMYRYLKNQYYNG-EALSQLPAHIATASKTGALNQ-TRNEIVFVHAPSGD-YAFAVLTKN -NNTPDNEAEVLIRKISNILWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Flammeovirgaceae bacterium TMED32 TaxID=1986681 RepID=A0A1Z8QBS3_9BACT --eDLDSKIINLLEQVEGDFAIAFQDLNRRENVfLLNENKQFHAASTMKVPVMIEMYHQAS -QGQFSLTDSILVKNESIVDHSTYKYTQIGKQMTLFDLMHQMIISSSNLATNILVEEV-GA -KNITASMQRLGAYDTEVLRGVEDQK-AYDLGLNNMTTAKDLMTILKSIALPLGETTQDQI -AMIDVLKAQEF-NDIIPRFLPVDVQVAHKTGSIT-GLHHDAGIIYLPNGETYVLILLSKN -LK-DFDQGTLTLAKISKLFYEHf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_11 TaxID=1916216 RepID=A0A292RR97_9BACT ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_3 TaxID=1916217 RepID=A0A292R422_9BACT ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. CH30_1T TaxID=2604836 RepID=A0A5A9E524_9BACI ----LEERILDAIDKCIGRVSVAI-DLPS-HSI-QFNNDTPYSAASLIKVPILLEGFRQAE -QGKIDLNEMVMVPKECRVGGAGVLSTLSENILTVEDLLTLMIIVSDNTATNLIIDRI-GS -EAINNLCNSLALKHTKLSRKLMDFQ-AIDQGYDNFTSATDIINCLRILDQSPLFSEQSRE -KMLFILHQQQF-VTKLPARMDERVFIANKTGELP-GVEHDCAIVRCEEKT-AYIAVLIDG -LEEN-DSARDTIAKIGKFLYDY- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8NKH9_9BACT ----LDRRVRDEVAKFEGTVYLYAKNLDTGAEY-SFGGEERVRTASTIKIAIMIEAFARVS -EGKAKWTDDLVLTKEKKVSGSGILQEFTEGLLTLHDVVMLMMLMSDNSATNLVIDALGGA -DTVNARMQSLGMTDTRLMRKIGGGGDSLEGKKEGRTSPREMVMLVEKLERGEIVSPAVSK -EMIDLMKREQTQDGIWRELWR--LPRATKSGALD-ALRSNVGIIYHPRG-RIALAITCDD -MPEQNWTA--------------- ->[subseq from] Serine hydrolase n=1 Tax=Gramella sp. KN1008 TaxID=2529298 RepID=A0A4Q9V6P2_9FLAO ---ELDRSLEQLTRDFNGTVGVYVYNLETRQEA-GINSDSIFPTASIVKVPILAGLFDKIA -KGEFTLNDTLVYEAKRAYGGSGLMQFYKDSTTDLRTLAALMITYSDNTTALWCQELAGGG -EDINEVMKELGFRYTRVNSRTKGREEDWKKYGWGQTTPREMASLLFKIYDRQVVNPASSD -EMYRMLTNSFY-TDYALSQIPPYVQTAAKQGMVDR-SRSELVMVNAPNGD-YVFYIATKG -NKDNDNEAWKLHRKISAFLWNYf ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 47-3 TaxID=2486013 RepID=UPI000F76C7ED ---QLQQIAQKTVLAVPGTNSVYVKKFATAGTY--VANNRPQRAASVIKLFIMATAFQQIA -AGKFTLNEPYTLTAADKVGGSGVMQGSVGTKVTLAQVMQYMMDDSDNVASNIMLAKVGGL -AAVNAECRHIGTKDTIMARKLMDMQA-LAAGHDNMTSVADLGKLLSKLYQHRLVSPAADT -QMLALLAQNKN-HTKLPAQLT-GAKVYNKTGEFDYGVQNDAAIIANDHGA-FVAVVLAQG -GAQQAQ----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus mixtipabuli TaxID=1435342 RepID=A0A1Z5IA31_9LACO ---------KKCVTSASGDTSVYVSNLKTRQPV--IMNSQSQRSASVIKLFVMVETFRQIK -AGRLSLNQAVQISKSDRVGGTGELAQQNVSQLTVQRLLTLMIRNSDNSATNALIDQLGGL -NVINGEIKRLGCSDTQLQRKMLDYQ-ALKNGKDNQTSVKDVGSLLTKLYQHRVLGAPYDS -EMLQLLRYNAN-QSKIPALINQKATVYNKTGEFDYGVQNDAAIVKKGNQA-FVAVVLSQN -GTE--NKQISAMQQLGQALY--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga filiformis TaxID=104663 RepID=A0A1G8A514_CHIFI --rKLEKGLRELIKDFNGDIGIYVRNLKTGRYV-GINEDTIFPTASIVKIPILVGVFDKLE -KGELKYHQPLIYRDSIKYGGSGLMQFFKDSTTDLSVLLALMMSYSDNTTSLWNQALAGGG -QRINELMAQYGLSVTRVNSRTPGREAIRNIYGWGMTTPHEMAELVVKIRQGEIISKAASE -RMYRLMTHGYY-DETGLSQIPPYVQAAHKTGSVD-ASRSEVILVNAPHGD-YVFYVGTKN -NKTDENEAENLIRKISKYLWEYf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535X4L3_9CHLR -------------ATLPGEAGAYACDEDGRELF-GEGANELFPSASVIKLPLVMTLYADAA -RGLADLDERVEVGT--RVDGSGVLRHMRDAAMSLRDYAMLAVIVSDNTATNRLIDRI-GT -ERVNERMREWGCPLSRLERRMYDFEAA-RAGRENVMTPRETASLLLRLVRGECEDRATSD -AVLAILAQCQD-RTMLRRYLPYTAIVANKTGTLDE-SRNDAAIIRGE--RAVVVAAFTKE -LRDTEA----------------- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8T3Y5_9BACT ----------------------YIKCIETGEEI-AINADETMDTMSVIKIPLMAEVFRQIE -AGKFALTDRVTLKEAEKRPGTGVIRSLDAGALTIKDLITLMIIVSDNTATDMLFEKVGGT -DPVNKLMQSYGLNTIKATGPTDVWFKTEGKTPFGLSSPRDLGKLLEKISRGEAVSKQASD -QMLRIMRGQLY-SSRLPKYIT-GFGIPHKTGDFLPYIGNDVGILESANR-HIVISVFTAR -HNGIGPNMEDAIGRIAEQVANFf ->[subseq from] Uncharacterized protein n=1 Tax=Atopobium vaginae DSM 15829 TaxID=525256 RepID=F1T3K7_9ACTN --kELQQQIEELTQPYGSSVSVCIIDASNGNYC-HVNSDKAFVSASMIKLAVLCEYMHAVD -NGQLDPADRVTLKNMKVVGGTGLIQTERHASYSYDELCRYMIMYSDNTATNVLINKL-GQ -DAINERVQALGCKNTSLNRQLMALNTN----TENWISARDAATILYKFKNGTAASSTICA -KALEYLSKQTD-NEGMAEGISSG-AFAHKTGSLRS-MRHDGGIVLG--KHPYVIVALCDI -GAGN---ANRLMKEIAQ------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5V3D7_9BACT ---SLRNELEKIAGESKARISVAVLDLESGFRF-SLAGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDDPLHVRNRFLSIGFPFRYRAIGRTVKISALAEGMIAASSNLATNLLLDFV-GV -EYARNVLRDAQVSGVELRRGVQDENA-HERGIDNEVTADGLLALLCAV-RGDFLKQQSRE -EIIRILLAQRF-NSMIPAGLPPHATVAHKTGEIST-ACHDAGIVYLPEREPYIVVILTEF -DA-EKDGRYQTLVGISNLIYR-- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140A337F ---ALRAELETLATTSPGRWAFAVRE--SGHQLaSVNGDTVMPAASTIKVALMLFVLRDIA -VGRRSLDDVLDVP-DVRAGGAGVLNALPSVRLRLDEVVELMIVVSDNTAANMIIDLL-GA -PALDKRLAELGTTHTRLQRRLMDLEAA-KTGLRNVTTADDQALLLDRLVGPGLLPPELRE -LALGVLGRQQF-NDRMPARLGADVVCRHKTGEIT-GVRHDVGVLEFDGRQ-VVLAALGSE -LDERPGPAADIIAEAAATVV--- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. O9 TaxID=1233460 RepID=UPI00136A4588 ----LYNVLKPLLDAHHGDAGVYVQHLKTGRTV-AINADTVFPTASMIKIPILAGVFKRIG -EGGLQYRQLLTYRDSLLYEGEDLLGSFRDSQITLDKVVMLMLTMSDNTASLWLQSLAGGG -AVINEWLAQQGFEHTRVNSRTKGREENRRIYGWGQTTPREMATLMKRIYKGEVVSKAGSE -RMYRNLTRNYW-DTEGVLMIPPGIRTASKNGAVDE-SRSEVLMVNAPHGD-YVYCIITKN -NKNRDNEAWQLLRKVGAAIWHHy ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Gastranaerophilales TaxID=1906119 RepID=A0A292SCK1_9BACT ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMILTNYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Akac8 TaxID=2563106 RepID=A0A4S3GH18_9ACTN -----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCVLVALHEQAA -RGALDLAEQVECGPKERTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHSFGEMLAALDPERTNRSTPRDMTRLLGAVWRDEACTPEHGA -AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] hypothetical protein n=1 Tax=Luteitalea pratensis TaxID=1855912 RepID=UPI0012FF688D -------------SSVDGSVAYLVVDVTSGQRF-ARRADEPFPTASAIKIGILYELFVQVD -AGREVLDDPKPLPEASRAGGSGIINRLRSPVLSLRDHALLMILLSDNTSTNVLIDTL-GM -DAINAHMQALGTSGYRLRRRMMDSAAAARG-DENVASASDLVTVMDAIRTGRGLRPESQA -EAIRILREY--GPTSVRAGIPADVPVATKPGGLD-GVRSEVSWVDVKGR-PYLLCVMTSF -LA-DDQAGEKAITEISRTSYQYf ->[subseq from] serine hydrolase n=1 Tax=Anaerosalibacter massiliensis TaxID=1347392 RepID=UPI0005B2BFAE -----KEDLIKLCKDIPGDIGFYYKDIKSKKVI-SFNENQLFIAASVIKIPVLVETLKQVE -NGNINKDHKVKVLKKYKVPCGALTYMHDDLEVTIEDLYTLMIIHSDNTATNMLVDML-GM -ENINNTLKDLGCNNSKINRLLFDAKAQ-NEGIENYITPYEIGYLLEKIYDGEIISKSISK -EIERILKLQRL-NHKMPYLLPQNIEIGHKTGEDC-GITHDVGIVYSK--KPFIFCFASNN -ID--VIKAEDLLRKMAFICY--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000990FCDB ------QSVEEIINSTQARISIAVE-IDEQRII-EKDSDREYLSASLIKIPIMMEAYRQSE -LGTICLTDLIEIKDFQKVGGSGVLHSLTGGTLSIKDLITLMIIVSDNTATNIMIELL-GK -DNINQFCRDIGAHHTKVERKLMDEQA-KAKGYENITTASDMICLLKELDQNEILSKNSTL -DILKCLSAQQF-RHKLPGLMDQDMKIANKTGEME-GIEHDVAIIHYGGK-KAYIAVLIDQ -LEQN-FLGQVSITKIGESVYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5JDE7_9BACT ---TFNEEVERLSAGSKARIAVAVHDFQSGSRF-SLRGDRWFHAASTIKVAVLLAIFRAAD -EGRVHLDDSLHVRNRFISAGFPFHYQLVGRTAKISTLAEGMIAASSNLATNLLLDFM-GV -EYARKVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVSLLSAV-RGDFLRNESKE -QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EGNGRREIVATISVAIYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_55_10 TaxID=1805420 RepID=A0A1Q6VBA5_9BACT --------------------AVAVHDLESGLRF-SLEGDRWFHAASTIKVAVLLALFRAAD -EGRVRLDDSLHVRNRFISAASSFHYQAIGRTAKISALAEGMIAVSSNLATNLLLDLV-GV -EYARKVLRDAQVEGVELRRGVED-HAAHERRINNEATANGLLTLLSAL-RGDFLSSESKE -QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DL-EQNGRRETVAAISEAIYR-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A354YKF0_PSESP ------------------------------------------------------------- --------------------------------------------------ANLLFGVVGGP -PEVTAFRRASGDTVSRRDRLEPGLNSFAKGDPRDTTTPAAMAATLQRVVLGEVLQPASRQ -QLADWLIDNETGDACLRAGLGKRWRVGDKTGSNGEDARNDIAVLWPVGGAPWVLTAYLQA -GAISYEQRASVLAQVGRIA---- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter flavus TaxID=1679497 RepID=A0A2N5D1W6_9CAUL -heAMSHKLTAIAERAPGDLGVAVQDLSTAQRA-AVAGEQLFPLAGIWTAALGAAVLAEVE -AKALSLRETLTIDDVDLSPPSGVADAWPGRRWTVEDLLKRAVAGGDNTAADVLMKRIGGP -GAVTAWLDLKKVENFRVDRYARQLTPDYLADPHDTTTPLAAVRFLEALNQGELSGQEGRR -RLLRIMEAAA--GDRLRPALPAGARLAAITSATSTAADNTLAMVRLKDGRRFALAIFLKA -SPLEESDRDALVLEVMRTVLQ-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus murrayi TaxID=68910 RepID=UPI0009FEE0BD -------------RGYGGEVGLLVTDLAGTELF-ALNADRSFPAASTIKVPLLVQALEEAQ -AGRLDLGARVCLQAEDRVPGSGVLHELDPGLLSWRDVLTLMVVVSDNTATNLLLDRL-GL -GAVNAWLLERGLSGTRLQQPPERQNAAQRRGERNRTTPRDQVRLLGQLARGELLDAPHTE -LALSILARQQF-RDLLGRHVPRDYRVASKSGELR-GIHHDVGLLLTP--RPLVVALLSEG -GTD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8TXG8_9BACT --eTLDEKIRAAIAGFPGTVSLFAKNLDSGATY-GLHPDERVRTASTIKLPILAATFAAVQ -EGKVKWADLSTLHDSDKVSGSGVLGEFSDGVLPLADLAHLMIVVSDNTATNLVLDRI-TA -DYVNEQMDKLGLKATRAMRKVRGDGAENQRFGLGSSSPREMVTLLEKIERGEVVSAEASR -EMLKILKRQQD-HNGIARRMG-DMPVANKAGALDH-LRSDVGIVYSPGGR-IAMAITCED -IP--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. Mgbs1 TaxID=2485489 RepID=A0A433WC53_9BACT ---RLYNVLKPLLDAHHGDAGVYVQHLKTGRTV-AINADTVFPTASMIKIPILAGVFKRIG -EGGLQYRQLLTYRDSLLYEGEDILGSFRDSQITLDKVVMLMLTMSDNTASLWLQSLAGGG -AVINEWLAQQGFEHTRVNSRTKGREGNRRIYGWGQTTPREMATLMKRIYKGEVVSKAGSE -RMYRNLTRNYW-DTEGVLMIPPGIRTASKNGAVDE-SRSEVLMVNAPHGD-YVYCIITKN -NKNRDNEAWQLLRKVGAAIWHHy ->[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013D83C4C ----VTDRIRAVFADAGCTGWLHARRCGSAAEI-SVDGRDRVVTASVYKLVLFVAFCRRVD -AGLIDPRAQLTVDPADCTPPTGLAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWEGGVLSPEQTG -FVRSVMGKQVW-PHRIAAAFPRGVSVAGKTGTIGV-IRNEVAVVEFPAEYPVAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteriales bacterium CG07_land_8_20_14_0_80_59_12 TaxID=1974045 RepID=A0A2M6YX28_9BACT --dTLEESIAALAGTFGGRIGVAARDLKTGRTI-LVDADSLFPTASVIKLPVLVALFDKFR -TGALHPDDTVSLTDSLKYGGSGVLQFFSGDALKLIDAAMLMIVLSDNTATNLVIDTFARL -AAVNSLMERFGLKHTHLLNKVMSWKTKTPESIRGVSTPADMLLLLERITAGTAVDSASSR -QMFDIMKNQQD-VTMAARMLPEQIVVANKTGWVSE-TKVDVGIVSSPAT-RYAYAIFADN -STDTDNRAVLAVARASRIIYDAf ->[subseq from] Uncharacterized protein n=1 Tax=Novibacillus thermophilus TaxID=1471761 RepID=A0A1U9KBT0_9BACL ----LEKRICETIKDYRDRFFIAIST--DEGTI-QLNADRQVRAASVVKVPIMIEAFRQVE -AGSVELDQPIDIDEGSKVGGCGVIKYLTRSNFTFRNLLELMVIVSDNTAANLVLDKV-GV -NSVNQLFEQLGCRNTQIERKFMDAE-AIEAGRDNYTSASDMVTLLKIIGETNAITQSSRS -QMLEILSRQQF-RQKLPCYSDSGVRFYNKTGEIP-GVEHDVAIVQRG-KARIYAAVLTQG -WQN-NGMAQRYLAEIGKHLIA-- ->[subseq from] serine hydrolase n=1 Tax=Terrimonas ferruginea TaxID=249 RepID=UPI00041E4A75 --kKLETRLREAVSGFNGDIGIYVKNLKTGKIA-VFNADTVFPTASIVKVPILLGVMQKLE -RGELFYDSTITYRDSLLYAGEDILGSFKDGEIRLKKVMMLMMTTSDNTASLWLQGLAGGG -TRINQLLDSLGFKDTRVNSRTPGREDIRKIYGWGQTTPKEMGEIFERIYRNQVFSPAACD -RMMRCMGRNFWDQEEAISVIPPYIEVFSKNGCVDQ-SRNEALLVNAPNN-PYIFCIFTKN -NKRKSNEAWTLTRKISTMLWEYf ->[subseq from] Serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=A0A5R8NCB6_9NOCA ----VTERIRAVFADAGCTGWLHARRCGSAAEI-SVDGRDRVVTASVYKLVLFVAFCRKVD -AGLIDPRAQLTVHPDDCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -GAVEDLLDELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLHLVWAGGVLSPEQTG -FVRSVMRKQVW-PHRIAAAFPRGVAVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLAVVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. RM TaxID=2316359 RepID=A0A418QGL5_9DEIO -------------SGFPGAVGLRVTDLSGTELV-AWNADRVFPAASTIKVPLLVFALQEAQ -AGRLDLSARVTVQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV -DAVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRALVAGEVLDGAHTA -LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSGG -GADPR------------------ ->[subseq from] Putative beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67P40_SYMTH ---DLTAILERVVSDLPGTIGVYVTDLATGRSA-GLNPMAEFYAASTIKVPIAMAVLWLAD -RRRISLDQTIAYQPEDYQAGTGILQATIQPGVSVRRLLELTITVSDNIARNMLERFI-GS -GTIRNYMLSLGVAPA-YDP----LET--------PVTPYGMNQVLIALDSGRGLSPASTR -MLLRWMEEAVF-RRRIPRYLPESAVVATKIGSRDD-EFHDVGLVYAPDR-SFAISVFTKG -MT--EAQAEEAIARIAEAVYW-- ->[subseq from] serine hydrolase n=1 Tax=Novibacillus thermophilus TaxID=1471761 RepID=UPI000989C41F ----LEKRICETIKDYRDRFFIAIST--DEGTI-QLNADRQVRAASVVKVPIMIEAFRQVE -AGSVELDQPIDIDEGSKVGGCGVIKYLTRSNFTFRNLLELMVIVSDNTAANLVLDKV-GV -NSVNQLFEQLGCRNTQIERKFMDAE-AIEAGRDNYTSASDMVTLLKIIGETNAITQSSRS -QMLEILSRQQF-RQKLPCYSDSGVRFYNKTGEIP-GVEHDVAIVQRG-KARIYAAVLTQG -WQN-NGMAQRYLAEIGKHLIA-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus obstructivus TaxID=1914540 RepID=A0A1L8ZGR2_9BACI ------QSVEEIINSTQARISIAVE-IDEQRII-EKDSDREYLSASLIKIPIMMEAYRQSE -LGTICLTDLIEIKDFQKVGGSGVLHSLTGGTLSIKDLITLMIIVSDNTATNIMIELL-GK -DNINQFCRDIGAHHTKVERKLMDEQA-KAKGYENITTASDMICLLKELDQNEILSKNSTL -DILKCLSAQQF-RHKLPGLMDQDMKIANKTGEME-GIEHDVAIIHYGGK-KAYIAVLIDQ -LEQN-FLGQVSITKIGESVYEY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. SYSU G01002 TaxID=2652445 RepID=UPI001291ABED ----LKEEILRLVSQCDGRVSVRIEL--NGEAI-DIKGNNVYSSASLIKIPILLEGFRQVE -AGKLQLDRVYELKDEEKVGGAGVIQALHGQNYSLLDLMTLMIIVSDNTATNRLIDII-GM -DSINSCISSLDLKHTVINRKMMDFIS-LQQGKDNLTTAADIVACLRKIEDASFLTPDSRE -KILGILHHQQL-LDKLPVLIDKEIWIANKTGELP-GVEHDCAILKYKGK-TLYVAVLVDQ -LR-DKKAGRAVISEIGKM----- ->[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A352FLS7_9BACT --nSLDSQIRAEISPFKGKVFVFAKNLDTGQTY-SYNGDERVRTASTIKVAVMIEVFARVA -EGHAKWTDELVLTKAARYAGSGILPEMSDGLLSLQDCVRLMMLLSDNTATNMVLDYL-GT -DAVNERMNSLGFKSTRIMRRVGGGGESKEGKLPDATTPREMVEILEKLARGQIVNETASK -EMIDLMKREQA-HYAIGRTIP-ETTVATKYGALD-ALRSCLGIVYSKQGK-IAMAITVDE -M---------------------- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D29818 ---SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKEIDGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAA-------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Actinobacteria TaxID=1760 RepID=A0A329QFQ1_9ACTN ---ALQRDIGTLATSAPGRWGFAIRE--QGRAVaSINGATAMPAASTIKVALLIMALQEVA -AGRCELDRSLPVP-ERRVGGTGVLRLMPSVGLRLDETLELMIGVSDNTASNMVLDML-GL -DDVTGRINALGARNTRLERHMMDFEAS-RSGRDNTTTADDQALLLDLLTGPDLLPDHLRQ -LALDILGRQQF-NDRIPAGLGPDVGCRHKTGELA-GVRHDVGILDFDGR-SVAFAALGSE -LRTGTGPAADVIARAARAVVD-- ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382F6F4_9ZZZZ ----------------QHEIGVAYLNLDSGDTF-FHNEKTVFHAASTMKTPVMFQIYRMRD -AGQLSLEDSLPVINESIVDGSNYSMGNINNKMAVRHLIEAMITTSSNLATNILIELA-DP -EAVMATLKETGADGVSVIRGVEDLKA-FDQGLSNRTDAYGMMMAMKAVFDSQFVSVKSRQ -EMIGILKSQQF-NEMIPAGLPAGTSVAHKTGRIT-GITHDAAIVMHENDSPFVLVILTRG -WA-DYTLATGAGIEITKAVFQY- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus laterosporus TaxID=1465 RepID=A0A502IL83_BRELA ---TLGSQMLEVTEKAGGEWAIYIEDLSTNESF-MHQEKQPFYAASLIKVPIMSTVFQAVH -EGCFSFEDTITLRAEDLVGGAGVLQHLTPGTITICDLVMLMIIQSDNSATNILIDLV-GE -ENIRSMLHNTNMSNSLFYNKLMVIPAKLEG--TNTITAEDMAKHFRLLATGKIISYDASL -KMLSILKKQQV-RDAIPYTFPDPWELANKTGSVTD-LQHDVGILYVGQHA-ILLAFLSRG -LD--NNSARQTIAKLGKMVFDQy ->[subseq from] Beta-lactamase class A n=1 Tax=Aneurinibacillus migulanus TaxID=47500 RepID=A0A0D1Y2E2_ANEMI --kQLDAYISRLIEETCGTWGIVIEDLDEDKRW-EWNTQESFLAESIIKVPVMAAAFAAVE -KKQFHLHDYVCLKKEDMVGGTGVLQHLTPGVLTIYDLITLMIIQSDNTATNIVIDLV-GM -ECIQETLEELGMEKSQFHRKMMIYPVH--IESKNVITADDASTLLKKLATGTFRSRHACE -QMIQILKKQQI-CNGLSSMLPPGWEFASKSGWDDD-RQHDIGILYTGQR-TFTISALSKG -GN--SLQAKQALGKIGLVVFE-- ->[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes/Chlorobi group TaxID=68336 RepID=A0A350PBD4_9BACT ----LQVKILNRLVGIEGDFAIAYKDINDAEKHiLINADERFHAASTMKTPVLIELYKRAE -NTDLNLEDSILIKNESIVDGSLFTYLNLNKNTTFYALAYEMITRSSNLATNILIDYL-GA -ENITNTMRDLGADSINVLRGVEDLKA-YRQGLSNSTTARDLLVIFDHLSTGTLISKKANV -EMLKILKDQVY-NDMISAKLPKGTPVAHKTGWITN-VHHDSGIVFTGNDEGYILVFLSKN -AP-DRDAVLEASADISRMIYDSy ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium 13_2_20CM_70_9 TaxID=1805207 RepID=A0A1Q6WKG4_9BACT -------QLRARIARAAQAVGLYYRSLARPDSV-LIGANLRFHAASTMKVPVMIQIFRDAD -AGLLTLDDSLVVHATSLVDGSPFDYLRLGGKASVRELLELMITRSSNLATDILIERV-RA -PRAQASARALGAWSIQVLRGVEDGK-AYRAGLNNTTTARDLGALLAAIAQHRAASPAACA -AMLAILSRQEF-NEGIPAGLPPGIPVAHKTGWIGQVVYHDAALVSPPAGGGYVLVVLTGG -LQED-SVAYGLVRDLSHLVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga caeni TaxID=2029983 RepID=A0A291QW43_9BACT --kALTKELSQIIKDFRGQVGIYVEHLGNGKTV-AINADSIFPTASMIKVPIMIGVFNKID -RDSLQYHQDLIYKDSLLYPGEDILGSFKEGAIQLSKVMMLMLTMSDNTASLWLQSLAGGG -SRINTWLEEHGYKITRVNSRTPGRAANQALYGWGQTSPSEMADLMKRIYKGELINPVTSE -RMYRNLTRNFW-DTEGLAMVPKNIRTASKNGAVNE-SRSEVIMVNAPSGD-YVYCICTKN -NIDQDNEAKQLLRKVALAIWKHf ->[subseq from] Beta-lactamase class A n=1 Tax=Tepidanaerobacter syntrophicus TaxID=224999 RepID=A0A0U9HQ47_9THEO ------ETVQDLIKDVDGVCSVVIDSTWSDEKI-FINEDKIMSSASIIKLWILWKLYAESE -RRDIDLKKKIPLKDENKTTGAGVLQYMNSGLLSLHDYATLMITLSDNTATNILIDYL-GM -ESINQEIKKLGMPNTCLQRKMMDMKAR-SCGKDNLTSAKDIYDFFVKLLKGHDISAQSRN -EMIDMLLCQQF-NDRLSLYLPEDIQFAHKTGGLF-GIEHDAGIFFINDTK-VIIVVMMSN -LKN-NADGLKVHNALGAAVYNYf ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga TaxID=79328 RepID=UPI000DBA2098 --hKLEKGLKDLITGFHGDVGIYVKNLRTGRYA-AINADTIFPTASIVKIPILVGVFDKIE -KGELKYHQPLIYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTASIWNQSLAGGG -QRINELMEQYELAVTRVNSRTPGRAEIWKVYGWGMTTPREMATLLVKIRNGEVISKAASE -RMYRLMTHGYY-DETGLSAIPPYVQAAHKTGSLD-ASRSEVILVNEPRGE-YVFYVGTKN -NKTDDNEAQVLIKHVAAYLWKYf ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium 13_2_20CM_54_12 TaxID=1805419 RepID=A0A1Q6VME2_9BACT ------------------ATAVSVHDLESGLRF-SLRGDRWFHAASTIKVGVLLALFRAVD -EGRVRLDDSLHVRNHFFSAGSAFQYQAIGRTAKIAALAAGMITASSNLATNLLLDFL-GV -AYARNVLRDAQVQGVELRRGVED-HAAHEKSINNEATADGLVALLSAL-RGDFLRSESKE -QAIRILLEQRF-NSMIPAGLPPHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EREGRRETVAAISEAIYH-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces mutomycini TaxID=284036 RepID=UPI0009A04DCF ----------------------------PSARV-TIDPDERLPMGSVYKVPLMVAFCRLVD -AGLIDPGRRLTLAPDDRVPPTGISILHDPVTMSLRDLVVLMMTISDNTAADAVLRVV-GP -DVVDAMCRDLGMPDTHIHGGVVTTFSVYDPAFKASTTPADMARLLRAIWTGQAASDERCA -FMRDVMRRQPW-THRLASGFPDDVTVYGKTGSFGS-MRHEAGVVELADGSTYTAAVFTQA -ARAKLPRADAVIGAAARTAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5785 TaxID=2690309 RepID=UPI001360F39B --gDVRRALRELFADAGVSGLVHVADVRRPEAAvTLGPDERVPIASVYKVPLMAAFWRQVD -AGVLDPRRAVTLDPSQRVAPTGISVLADPVTMSLRDLVVLMMTVSDNTAADAVLRAV-GP -AAVAQTCRALGLPDTHVHGGVAHTWDVYDPAHTSSSTPADIARLLHAIWTDRAASPAHCA -FMREVMSRQPW-RHRLASGFPDDVRVSGKTGTLG-ALRHEAGVVELPDGSTYTAVVFTRA -ARADLPRADAAIGTAARTAIE-- ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381NF87_9ZZZZ --kQLETTLKDKITTFDGVAGLSVKSLTSGKSI-SINGDEVFPTASTIKIHVLAKLFSLQE -EGEIDLSQRIRFTQNMYGSGSGVIHFLENDPFTILDVAILMMLASDNTATNTCIDVA-GM -EGINDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELILMMDLLHNEKP-TPKVSA -QVLRIMSKPKS--AYLNKAVGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF -SMVDSIAQEGFLIDLARNI---- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 17-4 TaxID=2486001 RepID=UPI000F780B50 ---------------LAGNTSAYVSRTDSDEEV--VRNNREQRAASDIKIFIMITAYEQAK -NNQLDLDGKYELSDDDKVGGTGVVQSMPAGTLTLRECIQYMIDESDNTAANIMIDAVGGL -DAVNDEISQLGLTDTQLERKLMDTD-ALNAGRDNMTSAKDLGVVLKQMYNHQLVSSGYDT -EMLNILAKNKN-HSKLLADLPAGAKGYNKTGEFSYGVQNDAAILESSKA-ALVVVVLSED -GQESTQ----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium sp. JUb20 TaxID=2485110 RepID=A0A4R3A6K8_9SPHI --kKLDRQLRALTQDFHGDIGIYVKNLKTQKEV-LIQADSIFPTASIVKVPILAGIFDKIE -KGELALDQKFTYRSSQQYGGSGLMQFFKDSSTDLATMIGLMISYSDNVTSIWNQQLAGGG -STINQLMDQLGLVNTKVNSRTEGRNEIWKKYGWGQTTPREMATLVALIFQGNVVSTKASD -KMYRYLGNIFY-NERSLSQIPAYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKNNEAEELTRKISHLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Aminobacterium mobile TaxID=81467 RepID=UPI0012EC2EC9 -------------ESFKGTAGVVIKDVQGKVKM-SVNGGEVFPSASLIKLPVLWTLFMEAH -SGKLSLDDTLVLKNEDKVDGGILHKYREGALLRLEDLALLMISVSDNTAANLVIDRL-GK -DRINNEIKDLGLHKTILGRKMLDFEAK-KEGKDNYTTPEDMASLLEIMLTSPKLPASLRE -RMLELMTLQKL-NSKLPSLIPIEGFLAHKTGELP-GSEHDAGIFFHGTETPVIVTILTKD -LS-SRMMGVELCSKIGLIIFEHf ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. IITKGP-BTPF85 TaxID=1338009 RepID=A0A0M3CAH2_9SPHI --kKLDRQLRALTQDFRGDIGIYVKNLNTQKEV-LIEADSIFPTASIVKVPILAGIFDKIE -KGELTLDQKFTYRSSQQYGGSGLMQFFKDSSTDLATMIGLMISYSDNVTSIWNQQLAGGG -STINQLMDQLGLVNTKVNSRTEGRNEIWKKYGWGQTTPREMATLVALIFQGKVVSTKASD -KMYRYLGNIFY-NERSLSQIPAYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKNNEAEELTRKISHLLWNYf ->[subseq from] Uncharacterized protein n=2 Tax=Halobacillus sp. BBL2006 TaxID=1543706 RepID=A0A0B0D4U6_9BACI ---SFKAEVEHTAASIKGNVSIVVKT--TDETI-EINSKKKVPAASTIKIPILMEAFRQVE -IGELDFDEKVDIPSHKKVGGDGVLKLLNNSLLSILDLMKLMIVVSDNTASNLVIDRL-GF -SNINNLCEKLDCTDTRLNRYFMDFE-AIKAGVDNATSASDMVQFFSEIKESQLLSRKSCQ -SIYNILKEQQF-ASGLPAYQKGDLEIANKPGMLP-GVQHDVGIFTYNSET-VYAAVLLSE -LD-DEEAGRRVIADMGRSIME-- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudomonas sp. PIC25 TaxID=1958773 RepID=A0A2A2DSE8_9PSED --eQLQGKILRLDQRTPGDLGVYIKHLGDDGEL-DHQAGRYWYLASAVKVPVAIATLQRVD -EGVWPLNQRLALRNEDKVDGSGLAWQDPGSEYDLKTLLEEMLQRSDSTAADMLINRI-GE -DELNRRIASMADQGTSLLRVRHELYRRYYARRLNAATLRAYGGMLEKLARGHLLSRANTD -LLLDLMGLDEYHAYRLEAGLGKDVPFAQKTGTQFE-RACHMGIIDPKSEQPIVIAACVEG -AGQ--EQAAQTLETLGSLV---- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6FIM6_9BACT ---TFNEEVERLSAGSKARIAVAVHDFQSGLRF-SLRGDRWFHAASTIKVAVLLAIFRAGD -EGRVHLDDSLHVRNRFISAGSPFHYQLVGRTAKISTLAEGMIAASSNLATNLLLDFM-GV -EYARKVLRDAQVDGVELRRGVEDYA-AHERGINNEVTADGLVSLLSAV-RGDFLRNESKE -QAIRILLEQRF-NSMIPAGLPAHAAVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -DS-EGNGRREIVAAISVAIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A0A2A9J997_SACEN ---RLREALEPGWADFPGRVGFAAWDLDEREPV-LFGARRVVHPASTIKVLVMLTALREVQ -RGGLALDTEVRFP-DERVGGAGVLKDLPGLRLELADAITLMISISDNTATNAVIEAV-GF -EAVGELAAELGCEGTQVQRLLMRVQDP----GRNTTCALDQARILDSLARGTVLPPRLTQ -HALWVLSRQQV-RDRLPALLPEGARCWNKTGEID-GSRHDVALIGDHERPRAVVAVLVDE -LA-DHRAGAARIAGLGLSVYE-- ->[subseq from] class A beta-lactamase, subclass A2 n=1 Tax=Bacteroides uniformis TaxID=820 RepID=UPI00125D4DBF -------------------------------TV-TVNNKSIYPMMSVFKVHQALALCNDFD -KKGSSLDTLVKINREKLDPWSPMMKDYSTPVLTVRDLLRYTLIQSDNNASNLMFKSMLNT -AQTDSFIAKIPRSSFQIAYTEEEMLADHDKAYSNYTSPLGAAVLMNRLFTESLISDDKQS -FIKNTLMECKTGVDRIAAPLKEGVVIAHKTGSGYNGAHNDVAFIRLPHNKYYTLAVFVKD -FKGNETQAAKIIARISNTVYS-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6G8I9_9BACT ------------------------------------NADRVFPTASSIKIAVLVELYRQDQ -KGKARLDDTYTFDPKDLVEDSRIMAGLTAGVVTNRDLAQFMVAVSDNAAANILIDRV-GK -DNVNATLRAVGLSKTMLRRKMIDIAAARRG-DENVATPEEMVRLLEVIYKGKVLNNEATA -ALTKQLSTLKQ--SYIPRLLPENVQVANKPGELE-AVRTDSGIVFATNR-PFAICVMTAY -DR-DERAAERAISEVALEAYRYf ->[subseq from] alpha/beta hydrolase fold domain-containing protein n=1 Tax=Prevotella copri TaxID=165179 RepID=UPI00142EE1FA --------------------------------YcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRTIENSATPKEMARLLEWFYLHRD-DNKNLS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK -SKEEKEVAEI------------- ->[subseq from] Serine hydrolase n=1 Tax=Desertiactinospora gelatinilytica TaxID=2666298 RepID=A0A2W2HKS7_9ACTN -------------RAAGVTGWLHAADIDTGAQV-GFGAHAAVPTASVFKLPLLVAFVRQAD -AGLLDPAERVAVPAADRVFPTGISAMLDDVTASLRDLCYLMIAVSDNTAADVLLSRV-GI -DAVNAMLDDLGLTATRVLHDCREMAAVLDPAGTNRSTPAELTRLLGMVWRDEAASAASCA -FVRRLLGLQVW-PHRLSSGFPDDVSVSGKTGTLPT-LRAEAGVVEYPDGGRYAVAVFTRS -HALNQPRADAVIGTAARMAIDH- ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000996D80D ------------------------------------------------------------- ------------------------------------------------------------- ----TDYLRELGDTVSRLDHYEPELHQVRPGDPADTTTPRAIAADYRTVILGDTLARDQRA -LLTDLLERNKTGGNRIRAGVPKGWRVADKTGTGQYGRANDIAIVWPPGSRPLVLAIMSER -SGREARPSEPLIAEATEHVT--- ->[subseq from] Uncharacterized protein n=1 Tax=Nocardia asteroides NBRC 15531 TaxID=1110697 RepID=U5E5Y0_NOCAS ---------------------LHARRCDSAAEV-SLGGDDRVVVASVYKLLLLAAFCRRVD -DGRLDPAARITVVPADCTPPTGLAALHDPVTLSFRDLATSMMTVSDNAAADVLLGEV-GL -GAVGDLVDELGLTGTRIVGGTADQHRAYDPSYASATTPEEMTRFLRLLWSGAVLSTASTE -FVRSVMGRQVW-QHRIAAAFPSGVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Niabella soli DSM 19437 TaxID=929713 RepID=W0EV13_9BACT --kKLKALIESAISGFHGDVGVYVHHLKKNKSV-AINADTIFPTASIVKVPLLAGVFQKIA -KGDLKLSQEFVYNAKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVAAIWLQELAGGG -ATVNPLMDQLGLPHTKVNSRTAGREDIWKKYGWGQTTPKEMAQLFTLIRQGKVIDARYSD -KMYRYLKNQFY-NGRSLSQLPATVSTICKTGSIDD-ARGEVVLVNAPGGD-FVFCILTKN -NKTDNNEAEVLTRKLASIIWNHf ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus grandis TaxID=57498 RepID=A0A100HLC2_9DEIO ------------ASGFPGVVGLRVTDLNGTELV-AWNADRVFPAASTIKVPLLVLALQEAQ -AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV -DAVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRALVAGEVLVGTHTA -LALDILERQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSGG -GADPR------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Stigmatella aurantiaca TaxID=41 RepID=A0A1H7YNA0_STIAU ----LNGLVETAARDFDGELSLYVLDVASGEEY-AYDAERPTYLSSAIKLGVMLEVMHQVD -AGRLSWDEPLTFTPDALRDMHRLHRAQPGDALPVSTLLEYMMVDSDNAAADLLIARV-GV -DAVKAQLAARGVQTGPVVSLLDERRRAFYAEQVNSAPMRQMGQLLRQVARCEGLSAASCT -RAHTLMRACQTGSARIAAGLPATAAWAHKTGTQHR-RACDMGFLTLPSGQPAVIAACTRN -FWR-VADAERLFALLGESVWR-- ->[subseq from] Uncharacterized protein n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A357FLV1_9CHLR --kQLETTLKDKITTFDGVAGLSVKSLTSGKSI-SINGDEVFPTASTIKIHVLAKLFSLQE -EGEIDLSQRIRFTQNMYGAGSGVIHFLENDPFTILDVAILMMLASDNTATNTCIDVA-GM -EGINDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELILMMDLLHNEKP-TPKVSA -QVLRIMSKPKS--AYLNKAVGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF -SMVDSIAQEGFLIDLARNI---- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=2 Tax=Planctomycetes bacterium Pla144 TaxID=2528003 RepID=A0A5C6CH84_9BACT ----IAQRLQELAGSVPGKIGYQIARVDGEVLY-SQLSDEVFPQASAIKVPLLMEVLAQRE -EAKIDWNAAHPILKKHQAGGSGVLFEFSDGCICTQDLCTLMIVLSDNTATNMLIELV-GM -ASVNQRMESLGLTQTRLQRVMMDMDAR-ARGEENVSTPREACQIMCLLAQGKFINQEISD -ELLGILRKPKS--TAIRNGIPAEIAVATKPGAIP-GVATEWALIEYPKQ-PYVAVFMGKE -G--SEKEFNEVFTEMTRCIH--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VBL1_9BACT -----------------ERLGIAFYDAETTLQW-SYNADLAFHAASTMKLAVLLAVFRQYT -RGKFSIYDRKPYMLDINRDTEGEIYDHLGRTMSVKQLAYYMITCSSNFATNLLVDVV-GV -PVIQTALDELKIDGIRVLRGVEDH-GAFEAGLNNEVTANGLLKLLRLVAEGKAYGEEASA -QMREILLDQRY-KSGIPAGLPQAARVAHKTGNIST-VHHDAGIVYLEGRKPYVLVILTQF -SSE--TGRTTAVADVSRDIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Coriobacteriia bacterium TaxID=2052159 RepID=A0A316RU59_9ACTN ----TEAAVARIISGHGDNVAVSVRMLDGSGSI-DINGDEPMQSASMIKLLVLAEYLDEVD -SGELLADETYTLDGGDIVGGSGTMQDDPGSEYTLDEVAHRMVAVSDNVGTNVLIGRM-GV -EAIQQKATELGLDGTNLAHKLMLPAN---DGSFNMISANDACRILERVASGTLASKGSCE -RAEDFLLDQED-DEGLAQGLPADVAFGHKTGTVD-GIRHDGGIVYAE--HPYVICVLTRG -LD--YGVANALMAQVSAAVYR-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus infantis TaxID=324767 RepID=UPI00101C2175 --nQLEKRLADILRQCPGNASLAVEY--GERAI-YMNSGRKYPAASLIKIPIMMEAFFQAE -EGVLDLSEQVRIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK -KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS -KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GIEHDCAIFAS-GRDVLYAAVLIEG -LS-SPEEGNHAIRLIG------- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus kimchiensis TaxID=993692 RepID=A0A0R2LNF7_9LACO ---------ADNLGSLAGTNGAYYYNLNDHVSS-GMSENTKIRAASDIKLFIMAVAFQKID -DGDLSLSDRYTLTDDDKVGGTGIVQSMQSGTLTYKDLINYMITQSDNTAANIITDKVGGL -SAVNEEITKLDLNHTDMQRKLMDQD-ALDEGRDNYSTAKDLGTFLTKLYQHNVVSKKYDN -QMLDIMANDSN-HTKLPSRINTDVTVYNKTGEYDYGVQNDAAIFKRGKK-AFVIVVMSEN -GKTD--DQKDAMGDLGAALA--- ->[subseq from] alpha/beta hydrolase fold domain-containing protein n=1 Tax=unclassified Prevotella TaxID=2638335 RepID=UPI000B979AA6 ---------------------------MNGDLYcGHQEDSVFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSKFEGARFTFAELIEWSLQQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVRLTEKEMKKNPHRAIENSATSKEMTRLLEWFYLHRN-DNKNLS -FIWNTMADCNTGKQRIAAILPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFLQK -SKEEKEVAEI------------- ->[subseq from] Beta-lactamase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2S1FJE0_KLEPN ------------------------------------------------------------- ------------------------------------------------------------- ---MTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQR -QLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRD -TPASMAERNQQIAGIGAALIEHw ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Bathyarchaeota archaeon RBG_13_52_12 TaxID=1797379 RepID=A0A1F5DJW6_9ARCH --sKLRRRLEEALERYEGVIGAAVKDLTTGESL-FINEDEVFPVASTIKVPILIEFHRRVE -AKTLDPMTPVDFVEAHRTGGSGVLKTLTPGAMPLIDYVTLMINVSDNSSTNYLIDLL-DL -SKINALIAELGLRETRLARKMMNMEA-FKAGKDSFTTPRELVAMFEELYTPRALSQFVCG -ETLKMLKKPKEGQGVIRNAIPDSVDVADKSGWVG-GATLDAGIVYQPSR-PYAVALLAKH -IPSSMVNALNTLTEMARLIQ--- ->[subseq from] hypothetical protein n=1 Tax=Geobacillus sp. (strain Y412MC10) TaxID=481743 RepID=UPI0011A5ED20 ------------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMQQVD -RGELSLADQVRVTPGDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM -DRVQQLMDQLDLRTMHLGRKMFAA--APSPTQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALS-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI001318A71E ----LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ -TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM -DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK -KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTDE -LPAP-EEGRRVIRTMGKLIGD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. AmelKG-E11A TaxID=1100822 RepID=A0A1C6LMD3_9ACTN -----RSRIRSVFTDAGVTGWMHALDLGDGAEV-AVAADTPVSTASVHKLCLAVTVQRFAD -EGRLDLDEQLESLPGDRTPGPTGLSMLSGPVMSVRDLLAMALTVSDNAAADLLIDRV-GL -DAVNDAMRALGLRRTVAVQTMRDLIAVLDPARANRSTPREMTRLLAALWRDEACSAERAR -ELRAVLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-VRNEAGVVEYPDGGRYAVAVFTRS -ARARQPAADAAIGTAARLAVR-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. OD32 TaxID=2136176 RepID=A0A2T3W7B5_9DEIO --------------GFPGRVGLRVCALDGTELV-ATGADEVFPAASTIKVPLLVMALQAAQ -TGRLPLHGRVTMTAEDRAGGAGVLHELAPGLLTWQDVLTLMIVVSDNTATNMVIEAL-GL -EAVNDWLAAHGLGGTRLVRPPHLQNEAQRRGERNATTARDQTEVLRALVAGEWLDPTHTA -LALSILERQQY-RDLIGRRLPRDFRVASKSGELL-GVRHDVGVLWTP--RPLLVALLSRD -GGREHPENRDVLALAAA------ ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D1DFE7 ---SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKALIEASMTYSDNTANNKIIKESGGI -KKVKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPA--------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes/Chlorobi group TaxID=68336 RepID=A0A3D4UV06_9BACT -----QVKILNRLVGIEGDFAISYKDINDAEKHiLINADERFHAASTMKTPVLIELYKRAE -NTDLNLEDSILIKNESIVDGSLFTYLNLNKNTTFYALAYEMITRSSNLATNILIDYL-GA -ENITNTMRDLGADSINVLRGVEDLKA-YRQGLSNSTTARDLLVIFDHLSTGTLISEKANV -EMLKILKDQVY-NDMISAKLPKGTPVAHKTGWITN-VHHDSGIVFTGNNEGYILVFLSKN -AP-DRDAVLEASADISRMIYDSy ->[subseq from] Beta-lactamase n=1 Tax=Synergistetes bacterium ADurb.BinA166 TaxID=1852916 RepID=A0A1V5I7Y3_9BACT --------IKKRAEEFSGTAGLVVHSLADGERL-AHNWDRVFFSASLIKLGILNTLFLNAA -RGELSLDEKIKLEEGMAVDGGLLHKMRPGVSWRLDDLALLMIALSDNTATNMLIDRL-GI -EEINRDFKRLGLENTVLGRKMLDFEAK-KAGRDNFTTAADTACILQTLHSGEELPPGYRA -RAMDILSAQKL-NNKLPGLIPVDQILAHKTGELP-GIEHDAGIFFFKSKMPVVAVVLTEG -HD--RQEAVELCARVGKTVYEAf ->[subseq from] Beta-lactamase domain-containing protein n=2 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A5K7XXQ7_KLEPN ------------------------------------------------------------- ------------------------------------------------------------- -------MHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Bacillus sp. LF1 TaxID=1499688 RepID=A0A0U1NQ97_9BACI ----LKYNMEEELHGFNGRVGLAIEI--EGESF-YFNSEKIFPSASVIKIPILIEGLRQSE -IGKINLEELISIPN--RAGGSGVLQILSSNVMTVKDLMTLMIIVSDNTATNLLIDLL-GI -EAINGSMKNMGLQDTVLSRKMMDFE-AIEHGLDNYTSPRDMISCLKVVNEGTYLSEASRK -IALEIMKYQQF-QDKLPGMIDDRMFVANKTGSFPR-VEHDCAIFKYKGRT-AYAAVLLDN -LD-DIFVGKQKISRIGKHIYNY- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus grandis TaxID=57498 RepID=UPI0009FB3A82 ------------ASGFPGVVGLRVTDLNGTELV-AWNADRVFPAASTIKVPLLVLALQEAQ -AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV -DAVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRALVAGEVLVGTHTA -LALDILERQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSGG -GADPR------------------ ->[subseq from] serine hydrolase n=1 Tax=Plesiomonas shigelloides TaxID=703 RepID=UPI0012615666 ------------------------------------------------------------- ------------------------------------------------------LEKIGGP -AALTAYLQSIGDNVTRLDRNEPTLNEAAKNDPRDTTTPNAINHTLNTLVLGETLSSTSRQ -QLKTWMQDNKVADGLLRSVLPQGFQIADRSGAGGFGSRGITALVWSAQQEPMFVSIYLTQ -TEATFNERNTAIVAIGKSIFDTf ->[subseq from] Beta-lactamase class A n=1 Tax=Gemmobacter megaterium TaxID=1086013 RepID=A0A1N7KLQ9_9RHOB --------------AGGARIGLVLSR--DGTVLfGHRAQERFLSASVVKIAIMVEIYRAAD -AGRLRLEAPVTVTAPMMAKGSGVMNRLVPGYVQVQDLLYLMMAISDNTATNLLIERA-GM -AAVNATMADLGMAGSNLGRPMLGRP-ATADEIENIAVPMDYDRLMQAILDGRAASQGACA -AMLDLLRAQQN-ERRLARHLPAGADWGSKTGTLD-GVVNDAGFLRTADGT-ACLSMFTQD -F-ARMVDAEEVLGDMAQAAF--- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Paenibacillus TaxID=185978 RepID=A0A1R0WHV5_9BACL ----------------GVRVTVSVADLSGNLGF-SIGSEERYRSASTIKLAIACALLQMVD -RGEVRLEDQAVVRDKDVVGGSGSLQLEVMPLINIGRLAKLMIAQSDNTATNVLIDMI-GF -ERVRAMLEGLGIHQTQLARKMFAPVQS--PELDNYADARELTYLLKLVYQGEVLSEYSRR -LLLLWMSRQEV-NTKFGAVLG-DMLIAHKTGEASN-VTHDAGYFLIPGRE-LAVAVMTEV -MTEAQRIGNPVIQRIAKIIYDQ- ->[subseq from] serine hydrolase n=1 Tax=Microbispora sp. GMKU363 TaxID=718014 RepID=UPI0006E22B7A --------IEQVFRSAGVTGWLHATDIDTGHEV-GLGADEPVVLASVFKVPLLIELYRQAE -RGTLDLTEAVRVPASSRTSGTGLTAMLDDAELSLRDLAYLMIAVSDNAAADVLLARV-GR -DSVNAFLAGLGLNGTRVAHDCREMFAVLVPALTSHGTPRELTRLLGMIWRDEAAAPASCA -AVRRLMGLQVW-PHRLAAGFPDDVAVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTCS -FSQNQPKADAAIGSAARIAIDH- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium RIFCSPLOWO2_12_FULL_67_14b TaxID=1797193 RepID=A0A1F2VNY3_9BACT ---TLHAVLARAATEFPGRAGIWVKHLTTGETA-GVRDGEMFNSASVIKIPVLVLALQMAD -RGEINLDERLTIRKEDIRGGSGIFRHHDAGLPTLRDVLLQMIITSDNTATDLSIAKVGGV -ARVNAWLKETGYDGQRLVQTTGELFAKTNGDRSGELSPKSIGLMLEAIEKKTIASAAGCD -AMLRMLRAQQAGQRRLNHYVT--VPVAHKTGDFPPVLANDVGIIYARSG-PIVVSFLGNA -ITGNYGEAEDRIGRVAQQIVEYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 22-7 TaxID=2709707 RepID=UPI0013D8BB9E --hTLKAEILTLASCCEGRVAVYIHT-E-DGFI-EKDADAIFSSASLIKVPILLAGLLQAE -KGLLQLEEEVEVTVSARVGGSGVLQAMARDLIKVTDLMTLMVIVSDNTATNLIIELL-GI -EKINQLFKDLGFNNTSLNRKMMDFE-ALKNGIDNTTTARDMVYGIKALAEQKLLSGKYTE -KALYILENQQFKNKLANTIDEEKVMVANKTGELP-GIEHDCAIFTHKGK-TVCAAVLVDR -LL-NQTAGKEVLSAIGSRI---- ->[subseq from] serine hydrolase n=1 Tax=Nocardia harenae TaxID=358707 RepID=UPI0009FE62DE ----AAHRIRAVFADAGCTGWLHARRCDSADEI-TVRGTERVVTASVYKLPLVLAFCRAVD -EGRIDPAARLTVDPAECTTPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEL-GI -GALHALLDELGLTATRIVGGTADLHRAYDPAFTSATTPEETTRLLRAVWAGAVLSPGQTA -FVQSVMRKQVW-PHRIAAAFPRGVAVAGKTGTIGT-IRNEAAVVEFPGEHPVAVAVFTRA -ARAELPAVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535AF53_9CHLR ---------RALIERAPFRVGVFARSADAETLL-EHDPDQALPSASVIKVPLVMTLYADAA -DGRIDLERRMRLG--DRVDGSGVLRDLRDVAFSLRDLAALTMILSDNTATNLVIDAV-GV -ESVAERLAEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD -AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVIRGPERT-VLVAAFTSH -VE-DHLAAEHLLGIIGRCA---- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Brevundimonas sp. TaxID=1871086 RepID=A0A519L2G1_9CAUL ------------------------------------------------------------- ----------------------------------VEQLMKGTVEVSDNPAANLLLKAMGGL -EAMQAFYRGLGDTSTRVDRFEPEMNRL--DGDKDTINPSQSAANMQRLFIDPALSAVSKA -MLLGWMTTSPTGMDRLKGGVPAGWRVAHKTGTGGYGPTNDIGILYPPSGAPVIVAAYYHA -MPTTDAQNAAVIAAATRLAL--- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus agri TaxID=51101 RepID=UPI0002A4D10F ---DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE -QGKARIDAQLALRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK -EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA -DMIAIMQKQQV-LHGLPSQLPSRWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD -VRA--EAALHTLGLLGRAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Staphylospora marina TaxID=2490858 RepID=UPI000F5BAAC5 ----LFRKLDEWKSTLPGTWGLVVEDLQTGTRW-TVNEDRLFYAASLIKVPIMAAVYREEA -AGRLTLEEEWPLSLEDQVGGSGILQHLSPGILPIRDLVTLMIIQSDNTATNMLIRRV-GT -ETIRKTMVELGMRHSRFHNPLMIVP--YPLENVNVVTAADMAACFRRIARGEAVSLHASR -RMIRTLKKQQD-AAGLPSLLPPKWEWAHKTGQVNR-ILHDAGILYVGGRA-LSVTALSEG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. T33-2 TaxID=2054168 RepID=A0A2N5GXT7_9BACI ------------IKKCKGRASIKLVI--DNYIL-KVDSQEPFPSASLIKIPILIAAYRQKE -LGLLDHQRRITVAAGKTVGGAGVLQALSGNLYTIKDLLTLMIIVSDNSATNLLINEI-GM -ESINDCLVKLGLAKTSLNRHMMAFA-ALQQGRDNYTCADDVVECLMTINNGMFLSKDSRS -EMLNILQMQQF-KDKLPALMDPGVTTANKTGELP-GVQHDCAIIQCNDKT-AIVAVLTDQ -LR-SHEDGRQTIRKIGKLVFD-- ->[subseq from] Serine hydrolase n=1 Tax=Aminipila sp. JN-18 TaxID=2507160 RepID=A0A410PU21_9FIRM -------------EGMRGKVGFYYKNLVTDETV-GFHEDELFRAASIFKFPLFAAMVYEKE -HNHVDFSEKIKILESEKIPGCGAVQHMTGDPVDILTLGKLMITISDNTAANALARHF-GI -EKMKGVFEKLGMKKTRLNRCLYDFESE-NKGIMNVFTPKEMGELLEKIYKRTLISKEASE -FIEDILLKQQI-NSKIPAKLPYAFKVAHKTGEEEK-TTHDVGIVYAK--EPFIVCFASND -TD--------------------- ->[subseq from] serine hydrolase n=1 Tax=unclassified Sphingobacterium TaxID=2609468 RepID=UPI0013DA994C --rTLEKKIKKEINGFQGDVGIYVQHLRTDKIV-SINADTVFPTASIVKVPILVGVFQKIA -QGELKLNQAFQYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELSGGG -TAINPLMDQLGLPHTKVNSRTPGREKIWEEYGWGQTTPREMAKLFTLIRNGQVIDARHSD -KMYRYLKNQFY-NGRSLSQLPAWVSTIAKTGSVDQ-ARGEVVLVNAPSGD-YVFCILTKN -NKTDDNEAEELTRKLSNIIWNHf ->[subseq from] Uncharacterized protein n=2 Tax=Clostridiales TaxID=186802 RepID=E7GH40_CLOSY ----LKLNVLNLCSRIEGKKAIVIEDLKTGEAV-EINRDEVFPAASLIKVPVLSALFRMAK -ESQIALDERIELEKDSRIGGFGILKDLGDGLPSVRDLAVLMITLSDNIAANLLIDRI-GM -SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG -DILDILFRQQC-NNKLPALMEGDVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD -ELADNREGIWLNQEIGKLI---- ->[subseq from] Beta-lactamase n=2 Tax=Bacteroides pyogenes TaxID=310300 RepID=W4P3V4_9BACE --------------------------IMNGDIYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS -FIWDTMADCNTGKQRIEAALPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFFPK -SKEEKEVAEI------------- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WSA7_9BACT ------------------------------------------------------------- --------------------------------LPLERLLELMLGESDNSASDLLLRLAGGP -AAVTNRMQALGIMGINVSRPEGQLILAFADDPRDTSTPDAMAQLLVRVERREVLEPASME -RLLQITTATQTGPLRLKGLLPAGTPVAHKTGTMG-ATTNDVGIITLPDGGHVALAVFVKG -STLDVPSRERVIAEIARTIYDYy ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus laterosporus TaxID=1465 RepID=A0A518V860_BRELA ---TLGSQMLEVTEKAGGEWAIYIEDLSTNESF-MHQEKQPFYAASLIKVPIMSTVFQAVH -EGCFSFEDTITLRAEDLVGGAGVLQHLTPGTITICDLVMLMIIQSDNSATNILIDLV-GE -ENIRSMLHNTNMSNSLFYNKLMVIPAKLEG--TNTITAEDMAKHFRLLATGKIISYDASL -KMLSILKKQQV-RDAIPYTFPDPWELANKTGNVTD-LQHDVGILYVGQHA-ILLAFLSRG -LD--NNSARQTIAKLGKMVFDQy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A523DZI9_9BACT --qTLEARLAAMLDALPAKSSLYAKHLPTGRVV-SVRGDELMNPLSVIKIPILALAFRDSE -AGKLDLAERYTIKPEDRRRGSGLIQTFAPGLPTYRDILTQMIVTSDNTATDIMIDRL-GL -ERVNELLSERGYRSTRLMTTTGGLFRGNPKEWLGQTTAKEMSKLLEEIYNAELTSHASSD -AMIGILRRQFY-RSRLPRFVRDGVGVAHKTGDWPPVAGNDVGILFHEGG-PTVVSVFINQ -NRGDFTKLEETIGQIAKELVAEw ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. NSP2.1 TaxID=1071072 RepID=UPI0003FF11D0 ---DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE -QGKARIDAQLALRKEDLVAGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK -EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA -DMIAIMQKQQV-LHGLPSQLPSRWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD -VRA--EAALHTLGLLGRAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis acidiphila TaxID=715473 RepID=A0A558A8E6_9PSEU ----VEGRLREVFRDAGVRGWVHARPVTGDGEV-GFGADDPVVMASTYKVVVLAAFCRAVD -DGEIDPREPVTVHPDTRTEPAGLSALRDAVTMTWRDLATSMITVSDNAAADAVHRRL-GA -GRVQAVLDDLALTATTVRGGTDDVHRALDPVYGSATTPREMTRLMSALWRGDVASPEQTA -FARQVLLAQVW-THRLRAGFPGAVRVAGKTGTLG-AVRNEVGVVSYPDEHPVAVAVFTHA -ARAEVPRADAAIGTAAY------ ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. xlx-73 TaxID=2654181 RepID=UPI0013DC1847 --rTLEKKIEKEINGFQGDVGIYVQHLRTDKIV-SINADTVFPTASIVKVPILVGVFQKIA -QGELKLNQAFQYSDKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWLQELSGGG -TAINPLMDQLGLPHTKVNSRTPGREKIWEEYGWGQTTPREMAKLFTLIRNGQVIDARHSD -KMYRYLKNQFY-NGRSLSQLPAWVSTIAKTGSVDQ-ARGEVVLVNAPSGD-YVFCILTKN -NKTDDNEAEELTRKLSNIIWNHf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces cyaneogriseus TaxID=68192 RepID=UPI00099B62B0 ---SIARRIGAAFAEAGVTGHLHAVDIDSGAEV-DAGADQPVVTASVHKLCLLVALHEQAE -AGRLDLAERVECPPDDRTSGPTGLAAMLDPVISLRDLAYLMMAVSDNGAADLLLRRV-GL -DAVNATTARLGLERTRALHTFRELFAALDPARTNHTTPRDMTRLLGAVWRDEACLPGHCA -AMRRILGLQVW-PHRLASGFPDDVRVSGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRS -ASATLPAADAVIGTAARMAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia cypriaca TaxID=882449 RepID=A0A543GFE0_9PSEU -------------AGVQGRLHAAPID-GPTREV-GVDPDEPAVMASVYKLPLLVAFCRRVD -AGEIDPRERVTVHPAEHTAPTGLSVLRDPVTMSWRDLACSMISVSDNTAADVLLRRV-GL -AHVNETLSDLGLERTRVLGGTADVHRAYDAVLASATTPREMTRLLAAVWSDRAASPERCR -FARELLGAQAW-QHRLRSGFPVGVRVAGKTGTLA-AVRNEVGVVQFDGERPVAVAVFTRA -ARAELPRADAVIGQAARLAVT-- ->[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR53 TaxID=925409 RepID=UPI000479DA06 --qHLQQQITQLIAGFHGDIGIYVHDLKKNRTI-AINADTVFPTASMVKVPILTGIMDKIH -KKELDYHQVLTYKDSLLYEGVDILGSFKNGEIELSKVMMLMLTMSDNTASLWLQTLAGKG -TRINELMDSLGLKVTRVNSRTPGREVNRNMYGWGQSSPREMASLMEMIVKKQVISDSSSQ -MMLRLLGRNYW-DENAISQIPSDVFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN -NKESTNEAWVLTRKLSKLLWEYy ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00038297F6 -----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCVLVALHEQAA -RGALDLAEQVECGPKERTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DTVNATTARLGLTRTRAVHSFGEMLAALDPERTNRSTPRDMTRLLGAVWRDEACTPEHGA -AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5UNY7_9BACT ---TLSEELERLGGESKARIAVALHDLETGFRF-SLRGDRWFHAASTIKVAVLLAIFRAAD -EGRLRLDHSLHVRNRFFSAGFPFHYESIGRTAKISALAEGMITASSNLATNLLLDFV-GV -EYARRVLRNALVDSVELWRGVEDH-AAHERGINNEATANGLLKLLSAI-RGDFLSNGSKQ -EVIRILLEQRF-DSMIPAGLPAHATVAHKTGEIST-ACHDMGIVYLPEREPYIAVILTEF -GQ-EIEGRRETVAAISELIYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Sporomusa silvacetica DSM 10669 TaxID=1123289 RepID=A0A259U919_9FIRM ----LSEQVKNFSTQKEAQYAIYVRPLNQAGQD-VVLNSHKMASASLIKIPIMIEAFNQKN -QGKLDFNERFTIRHAETVEGGSVYNLPDGTVLTIGQLVELMIVQSDNSACNILIDKL-KM -ENVNAMINKLGCSDTILQRKMMDFEA-VKQGRQNYTNVTDMANVLEKLYNSKCLDPKSDK -AMLEILKRQED-NLIIPAQLPHHIKVAHKTGELD-GMNYDCGIIYGQSHN-YILCMMAEN -VKD-E------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=A0A1I5GLM8_9FIRM ------------LQKITGKAGFYYKNLVTGEQI-TFQEDMPFQAASVIKIPILIEAFTRLE -TGSLHKTDLFTIKKQDKLPCGALTYMHDGLQVTLEDLYTLMIILSDNTATNLLIEHL-GM -DQINNTMQKLGCRQIKLNRYLFDSEKA-ALGIENYISAGDIAGLLEKMYHGELVSKEASV -EMLRILKNQRL-NGKIPFFIHGKADIAHKTGEDD-GITHDVGIVYG--KEPFIICFCGNE ---VDVPAYERLMQDISYALFK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. YR288 TaxID=1882766 RepID=A0A2M8YVQ4_9BACI --------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLSVTVKELVLLMLILSDNTATNMLIALL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKESLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGRIIS--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=A0A4P8XCF7_9BACI --------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKESLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGRIIS--- ->[subseq from] serine hydrolase n=2 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=UPI001402DB02 ----------------QHEIGVAYLNLDSGDTF-FHNEKTVFHAASTMKTPVMFQLYRMRD -AGQLSLEDSLPVINESIVDGSNYSMGNINNKMAIRHLIEAMIATSSNLATNILIELA-DP -EAVMATLKETGADGLSVIRGVEDLKA-FDQGLSNRTDAYGMMMAMKAVFDSQLVSVKSRQ -EMIGILKSQQF-NEMIPAGLPAGTSVAHKTGRIT-GITHDAAIVMPENDSPFVLVILTRG ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Niabella aurantiaca TaxID=379900 RepID=UPI00037F906D ---KLKTLIEKAVSDFHGDIGVYVHHLKRDRFV-AVNADTVFPTASIVKVPILAGVFQKIS -QNELKLSQEFVYDAKRAYGGSGLMQFYKDSATDLSTMISLMLTYSDNVAAIWLQELAGGG -AAVNPLMDQLGLPHTKVNSRTAGRQDIWKKYGWGQTTPREMARLFTLIRQGKVIDARYSD -KMYRYLKNQFY-NGRSLSQLPATVSTICKTGSVND-ARGEVVLVNAPGGD-FVFCILTKN -NKTDDNEAEVLTRKLANIIWNHf ->[subseq from] serine hydrolase n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=UPI000F4B44B4 -----------EFRDAGVHGRLHALDLDSGAEV-AAGADEAVVLASVFKVPLLVAFFRRAA -AGELDARAQVVLPPEARIAGATGTSVLLDEVMSLRDLACLMITVSDNTAADAVMDHV-GL -DHVNRAMAELGLDRTRIVGNARDLHAALDPALATRGTPREMTRLLAAVWRDEAAPPDACA -LMRRMLGLQVW-PHRLASGFPDDVVVSGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS -RSSAQPRADAVIGTAARLAVQ-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A1S2C783_9BACI ----------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEVFRQVD -EGLLTLTSVIQRTEKNTVGGAGVLGALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECARNIGLKKTVLNRYMMD-ETAVKQGVDNYTCASDIVECLREIYKGNFLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinocorallia herbida TaxID=58109 RepID=A0A3N1CS83_9ACTN ---------EAEFRDAGVHGRLHALDLDSGAEV-AAGADEAVVLASVFKVPLLVAFFRRAA -AGELDARAQVVLPPEARIAGATGTSVLLDEVMSLRDLACLMITVSDNTAADAVMDHV-GL -DHVNRAMAELGLDRTRIVGNARDLHAALDPALATRGTPREMTRLLAAVWRDEAAPPDACA -LMRRMLGLQVW-PHRLASGFPDDVVVSGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS -RSSAQPRADAVIGTAARLAVQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus pentosiphilus TaxID=1714682 RepID=A0A1Z5IZ26_9LACO ---------QRCAHSASGETSIYVDNLKAKHPViLHN--RTQRSASVIKLFIMVTAFRQIK -AGQLSLNQEVRVPKADRVGGTGELAQENVSQLTVSKLLTLMIRNSDNSATNVLIDRLGGI -NVINQEIKRLGCTQTQLQRKMLDYQ-ALKAGKDNVTSAKDVGSLLVRLAQHRVLGAPYDA -EMLQLMTNNAN-QSKLSALINKKATVYNKTGEFDYGVQNDAAIVKKGSQ-TFVAVVLSQK -GT--QRKQISAMQQLGKQLY--- ->[subseq from] Beta-lactamase class A n=2 Tax=Paenibacillus sp. VMFN-D1 TaxID=2135608 RepID=A0A3D9GSY3_9BACL ------------AEKDGIRMSVGIRDLSGHETL-LLGSQEPYMPASTIKLAVVSALMLQVD -RGELSLADQVRVTPEDVVGGSGSLQTSFPQDLTLERLARLMITQSDNTATNVLIDKV-GM -DNVQQLMDQLDLRTMHLGRKMFATA--PSPAQDNYIDAADLTELLGQIYQGSFLSVSSRN -QIIAWMARQEV-NTKFGAALT-DAPIAHKTGENAN-VTHDAGYFLVPGHE-LAVSVLLQV -TTEAQRIGNPIVQKAARAIYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7VY66_9CHLR ---KLIQRLNNIPNEFKGLCGVCIYDPDTKWYF-GINDDMTFPTASSIKIPILIKLLSDAD -KKLINLSDEIVITEQMKSRGSGVIHKMTGSVMTIENLAILMINLSDNTATNLCIDIA-NQ -KEINEMLSDYDFGTMKLNRKMQDYQ-AINEGKENIATPKEMNLILQMLDNKSLFNESVSN -KTLDILAINKS--TPISQPLPENIKVAGKTGGMP-GVRCETAIVYLKNRR-YILTVMTSY -GGQS------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_10 TaxID=1916229 RepID=A0A292RS03_9BACT ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMILTNYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRIWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAAGLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0792 TaxID=2032566 RepID=A0A2A3VGL1_9GAMM ------------------------------------------------------------- ----------------------------------------------DNMAIVGLRNAPAGE -ERLVALARALGVPRSALKASLEAVFDAYYRGDRNQATLPAFATLLERLAAGELLSADSTA -RMLEHMRGISTGDRRLSAGLPPGTDFAQKTGTQVR-RACNVGIVDADAGREGATVVLCAE -DFDALGQAEQAFQAFGRAL---- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A6B0XEA4_9BACT ------AALRQTAAAFDGRMGWHLEELTTGQVH-QYRADERFPTASVIKIAVLVELFHQAE -TGRLSLDDRHRLRGDISTHGSGVLQIAQDEPLTLRDYARLMMGISDNIATDFLMGLL-GL -DQINATLARLGCANVRAAATMGRYHYFGDSLENNVAAPGELASLLAAIYRGQIVSAAASK -AIIELLKTGRD-TRMIRHYLKSDVVVAHKYGSSGI-IKGDAGLVFLPGGPLVVVAFALAR -D--DGPAAAEAIAEITRLAV--- ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI0013A5AEE2 ------------------------------------------------------------- ------------------------------------------------------------- ----TAFLHNMGDHVTRLDSWEPELNEAIPNDERDTTMPAAMATTFRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYMTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] serine hydrolase n=1 Tax=Rufibacter roseus TaxID=1567108 RepID=UPI00082C3913 --tKLQQKLEALVKEFDGEVGIYVRHLKTGKAV-AINADTLFPTASMIKVPIMVAMFDKIE -RGEINPNAQLRYRDSLYYAGEDIVGNFKDSAVALGKVQMLSITTSDNTGSLWLQQLAGGG -TAINAWLEKNGFEKTRMNSRTPGRRKNWEQYGWGQTTPREMANLVTMIREGKAVSPAASE -RMYRNLGRIYY-DSYALSKIPPYVHTASKSGAVNQ-SKSEVVLVNAPNGD-YVFCIITKN -QKAPDNAGAVLIQKVSETLWKHf ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus faecis TaxID=862114 RepID=A0A5D0CUN6_9BACL ------------AATKGIRVSVGLKDLSGNEET-LLGSKEAYKPASTIKLALVAALMQQVD -RGALTLEDTVTVEPDDVVGGTGSLQKKFPQEVSLERLARLMITQSDNTATNVLIDVV-GL -KRVQELMDQLNLEVMHLGRKMFAAA--PTPEQDNFINAADLITLLDRIYKHSFLTEKSKD -TIIGWMLAQEV-DTKFGAALQ-GAKIAHKTGENAN-VTHDTGYFLVPGRE-MAVAVLTEV -TTEAQAIGNPVVQEIAKAIY--- ->[subseq from] serine hydrolase n=1 Tax=Anaerocolumna sp. CBA3638 TaxID=2696063 RepID=UPI001373AFDF ---ALQKAVEEEIKEAQAKISLYIKNLKTGEVLfQHKEDLSVVSASIIKVPIMVAALEEIQ -KGVLSKDTLVTVPKSTILEDSEVFE-YGERQYTLDELLVWMIINSDNTATNSLIDLL-TM -DKINQTCRQLNLKVTKLERKMLDFDA-VKLGYNNYTSAMDMCLIYKALYDKSILTSDLCD -YAVSILLRQRHKQNSMR-YITDEVKIAHKTGSLDF-LNHDAGIFYLKEND-YYFGAFVWD -AP-DDVYGMKWIGRVSKMVYEYy ->[subseq from] serine hydrolase n=1 Tax=Bacillus farraginis TaxID=254757 RepID=UPI0007170DEC ------QSVEEIITSTQARISIAVE-IDEQRII-EKDSDREYLSASLIKIPIMMEAYRQSE -LGTICLTDLIEIKDFQKVGGSGVLHSLTGGTLSIKDLITLMIIVSDNTATNIMIELL-GK -DNINQFCRDIGAHHTKVERKLMDEQAK-AEGYENITTASDMICLLKELDQNEILSKNSTL -DILKCLSAQQF-RHKLPGLMDQDMKIANKTGEME-GIEHDVAIIHYGGK-KAYIAVLIDQ -LEQN-FLGQVSIAKIGESV---- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536R0B4_9CHLR ---------RDALRSLPGEASAFACDLDGRELF-CERADELFPAASVIKLPLVMALYADAA -RGHIDLEERLPVG--DRIDGSGVLRHLRDVESSLRDLAMLAIIVSDNTATNRLIERF-GI -ARVNERMREWGCPHSLLARAMFDFEAA-KRGHENVMTARETAALLLRLMRGECEGRAASD -AVLALLAQCQD-RSMLRRYLPHGAKVAHKTGTLDE-SRNDAGIITGE--PTIVVAGFTRR -LRDTE------------------ ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A352NVK4_CLOSP --------IKEKIKNLKGKVGFCYKDLESGYSF-GVNEDDPFIAASIIKIPVLIEAYRKFK -EEDLSKNELVEIRESDRVPSCGAAYIHPGAKLTLKDLCILMIILSDNMAANILINKL-KM -DDINSTMKKLSLKKTRVNRILFDSDAQ-KSGKENYFAPGEILRLFEMMWNGSLISPDDSR -DMLEIFKLQQI-NYKMPYLLPEDICIAHKTGDDD-GITHDAGIVYAK--RPFILCFASNE -TD--VNETDEFIRQTTEEIF--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 218-3 TaxID=2559919 RepID=UPI0010F78C47 ---------QQTMGKLGGQNSVYIQ-TTTGQTY-QWHN-QSQKAASDIKLFILATVYQQVA -AGKLNLATTYTLKATDKVGGTGSLQGMATGSFTIQELLHYMMTVSDNTATNIVIDEVGGI -SAVNQEIKRLGASQTVLRRKMMDQK-ALTAGRDNVTSVRDLGQLLMKLWHHRLISTAADT -AMLKLMAANTN-HTKLPKLLPGTRTVYNKTGEFDYGVENDAAIFVQGQRA-VVLVALSQG -GQLS--QQ--------------- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A4FGH3_SACEN ---------EPGWADFPGRVGFAAWDLDEREPV-LFGARRVVHPASTIKVLVMLTALREVQ -RGGLALDTEVRFP-DERVGGAGVLKDLPGLRLELADAITLMISISDNTATNAVIEAV-GF -EAVGELAAELGCEGTQVQRLLMRVQDP----GRNTTCALDQARILDSLARGTVLPPRLTQ -HALWVLSRQQV-RDRLPALLPEGARCWNKTGEID-GSRHDVALIGDHERPRAVVAVLVDE -LA-DHRAGAARIAGLGLSVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. UR1 TaxID=1704277 RepID=A0A2G7H0K5_9DEIO --------------GFAGTVGLWVGTPQGEALA-TLNGDRVFPAASTIKVPLLVMALQAAQ -RGDLSLEDRVALQAADRVPGAGVLHELGAGLLSWQDVLTLMIVVSDNTATNLTIERL-GV -GAVNGWLGAHGLNGTRLVGKLDQRNEAQRRGERNATTAADQARLLRLLLGGDLLDPPHTA -LALSILGRQQY-RDLIGRGVPADYRVASKSGELT-GVHHDVGVIFTP--RPLVVALLSEG -GQREHPENRDVMALASA------ ->[subseq from] Class A beta-lactamase n=1 Tax=Clostridium sp. HMb25 TaxID=2044259 RepID=A0A2N0KCZ3_9CLOT ----LKLNVLNLCSRIEGKKAIVIEDLKTGQAV-EINRDEVFPAASLIKVPVLSALFRMAK -ENQIALDERIELEKDSRIGGFGILKDLGDGLPAVRDLAVLMITLSDNIAANLLIDRI-GM -SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG -DILDILFRQQC-NNKLPALMEGGVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD -ELADNREGIWLNQEIGKLI---- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus agri TaxID=51101 RepID=A0A3M8AJ30_9BACL ---DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE -QGKARIDAQLALRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK -EQIDRTMREVGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA -DMIAIMQKQQV-LNGLPSQLPAAWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD -VRA--EAALHTLGLLGRAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. PRKS01-65 TaxID=2697029 RepID=UPI0013DAFDD8 ---SIARRIGAAFAEAGVTGHLHAVDIDSGAEV-DAGADQPVVTASVHKLCLLVALHEQAE -AGRLDLAERVECPPDDRTSGPTGLAAMLDPVISLRDLAYLMMAVSDNGAADLLLRRV-GL -DAVNATTTRLGLERTRALHTFRELFAALDPARTNHTTPRDMTRLLGAVWRDEACLPGHCA -AMRRILGLQVW-PHRLASGFPDDVRVSGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRS -ASATLPAADAVIGTAARMAVD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia coubleae TaxID=356147 RepID=UPI00083244B5 ---------------------LHARRCDSVAEI-SVGGRDRVVMASVYKLLLCVAFYREVD -HGRIDPAGRLTIDPADCTPPTGIAALHDPITLSRRDLVTSMMTVSDNAAADVLLGEL-GL -AAVADMAVELGLTETRVVGGTADQHQAYDPAYASATTPEEMTRLLWRLWSGDVLSTESTE -FVRAVMRNQIW-PHRVAAGFPRGVVVAGKTGTVGI-IRNEVAVVEFPGEIPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5P0N1_9BACT -------------KRKARAIAVAIHDLETDFRF-SLSGDRWFHAASTIKVAVLLAVFRAAD -ESRLRLDDSLHVRNRFFSAGDGSIYHSIGRTARISSLAHAMISGSSNLATNLLLDFV-GV -EYARKVLRDAQVHSVELRRGVEDH-AAHEQGINNEATANGLVTLLSAI-RGDFLSNESKQ -EVIRILLEQRF-NSMIPARLPPHAAVAHKTGEIST-ACHDIGIVYLPEREPYIAVILTEF -D-ADRNGRRETVAAISELIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Xanthomonadaceae bacterium NML93-0399 TaxID=2032565 RepID=A0A2A3LLC8_9GAMM ------------------------------------------------------------- ----------------------------------------------DNMAIVRLRNADVGE -PRLEALARELGVPRSGLDASIEAVFDAYYDGEDNQARLPAFGLMLERLAAGELLSPDSTA -IILGHMRQITTGDRRISAGLPAGTDFAQKTGTQIR-RACNVGVIDPEAGEGATVVLACAE -DFDDISQAEQAFQAFGRVL---- ->[subseq from] Beta-lactamase domain-containing protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1K376_9ZZZZ ------------------------------------------------------------- ------------------------------------------------------------P -KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAE--------- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=A0A0E3UPQ0_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALAALLGVPRSQLKASLQAVFDDYYASGRNAATLPAFARLLERLVAGELLSESSTA -LLLGHMREIGTGGRRIQAGLPADADFAQKTGTQQQ-RACNVGILDPDRGDGATVVVACAE -DFGELAQAEQAFQALGRALAQ-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5S4Z5I5_9BACI ----LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ -TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM -DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK -KMLTILSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTYE -LPAP-EEGRRVIRTMGKLIGD-- ->[subseq from] Steryl acetyl hydrolase n=1 Tax=Prevotella copri TaxID=165179 RepID=A0A3R6BSH1_9BACT ----------------------------NGELYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVNKDSLDAWSPMLSIFEGMRFTFAELMEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKNPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDDSHLSIAIFLQK -SKEEKEVAEI------------- ->[subseq from] Beta-lactamase n=3 Tax=Clostridiales TaxID=186802 RepID=A0A174GDL8_CLOSY ----LKLNVLNLCSRIEGKKAIVIEDLKTGEAV-EINRDEVFPAASLIKVPVLSALFRMAK -ENQIALDERIELEKDSRIGGFGILKDLGDGLPAVRDLAVLMITLSDNIAANLLIDRI-GM -SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG -DILDILFRQQC-NNKLPALMEGGVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD -ELADNREGIWLNQEIGKLI---- ->[subseq from] Uncharacterized protein n=1 Tax=Atopobium vaginae TaxID=82135 RepID=A0A135P9T6_9ACTN --kELQQQIEELTQPYGSSVSVCIIDASNGNYC-HVNSDKALVSASMIKLAVLCEYMHAVD -NGQLDPADRVALKNMNVVGGTGLIQTERHASYTYDELCRYMIMYSDNTATNVLINKL-GQ -DAINERVQALGCKNTSLNRQLMALNTN----TENWISARDAATILYKIKNGTAASSAMCA -KALEYLSKQTD-NEGMAEGISSG-AFAHKTGSLRS-MRHDGGIVLG--KHPYVIVALCDI -GAGN---ANKLMKEIAQKA---- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7M3R2_9BACT ----LRDRLEARISRAPAQVGLYYRNLAGSDSI-LIGANLRLHAASTMKVPVMIQIFRDAD -AGLLRLDDSLTVHTASLVGGGAFTYALVGRNRSVRELLELMITRSSNLATNILIERV-GA -SRAQASARAMGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIATGRAASRGACD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAALVYPSAGVGYVLVVLTGG -IKED-SVGHNLVADLSRLVYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium sp. JUb78 TaxID=2485111 RepID=A0A4V2TQP0_9SPHI --kKLDRQLRALTQDFHGDIGIYVKNLKTQKEV-LIQADSIFPTASIVKVPILAGIFDKIE -KGELALDQKFTFRSSQQYGGSGLMQFFKDSSTDLATMIGLMISYSDNVTSIWNQQLAGGG -STINQLMDQLGLVNTKVNSRTEGRNEIWKKYGWGQTTPREMATLVALIFQGKVVSTKASD -KMYRYLGNIFY-NERSLSQIPAYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKNNEAEELTRKISHLLWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E6WQ03_9CHLR ---KLEDDLIDKLDQFPGVAGVSIKDLIXGNDI-SINGNEIFPTASIIKIHILTYLLKMAE -SGSIDINKRISVDKNKFTGGTGILKYLKGKPLTLRDIAVLMIMLSDNTATNICIDLL-GI -ENINSFISDMELSXTKLNRKMMDEK-AIIXGNENLSTPKELTKMLEKLYLG-LPSKAVSK -YVLEIMSEPKN--SCLNLSTPSDITVANKGGGMEH-VRGDSGIIFLENN-PYIISILTKS -CYKGSGFQEEYIMNIAKDVFEIf ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A3D4YJE3_9FIRM ----MKQRILEQIASMPGHNGMYFKNLITGEKI-EYRSDESFGPASVIKLPILMHICQLAR -QCQVRMDEKIRCRHADKLGGCGALRAFNDEPVSISTLCELMITISDNSATNLLIHRF-GM -DALNESFRQMGLSVTRLNRILFD-NEAASRGIENEFSPAEMGDLLEQIYRRKFVDETTSI -YIEDMLMKQQI-NHKIPGIIGDAAPIAHKTGEDE-GISNDVALVYAPE--PFVLCYAGNG -TN--VPEFENFIRK--------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 398-2 TaxID=2559920 RepID=UPI0010F5175E ---------QQTMGKLGGQNSVYIQ-TTTGQTY-QWHN-QSQKAASDIKLFILATVYQQVA -AGKLNLATTYTLKATDKVGGTGSLQGMATGSFTIQELLHYMMTVSDNTATNIVIDEVGGI -SAVNQEIKRLGASQTVLRRKMMDQK-ALTAGRDNVTSVRDLGQLLMKLWHHRLISATADT -AMLKLMAANTN-HTKLPKLLPGTRTVYNKTGEFDYGVENDAAIFVQGQRA-VVIVALSQG -GQLS--Q---------------- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga flava TaxID=2259036 RepID=A0A365Y1L3_9BACT ---RLQQGLQQIADNFKGTAGIYVQHLQTGEWA-SINGDTIFPTASIVKIPLLVGLFNKID -KGELGYHQSMVYRDSSRYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLLNQQLAGGG -AAINQLLEQYGLKDTRVNSRTPGREDNRKIYGWGQTTPREMATLLAKISRGEVISRAASE -RMYRLMTKGYY-DEQALTQIPPYVQAAAKTGSIDE-SRSEVVLVNAPHGD-YVFYVGTKN -IKDADNEAVEMIRTISAYLWKHf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus agri TaxID=51101 RepID=UPI000471F30E ---DLEKSLSAILQEAKGAWGVVVKELANGAYF-AHRPDELFIAESVIKVPIMAAVYAACE -QGKARIDAQLALRKEDLVVGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDLV-GK -EQIDRTMRELGMERSRYSRKLMIYPQD--VTENNMITAGDVARMLEQIACGGRFSRWASA -DMIAIMQKQQV-LNGLPSQLPSRWELACKSGWDT-GRQHDVGILSVQGR-QFAIAALSQD -VRA--EAALHTLGLLGRAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7MLB3_9BACT ---SLSDKIAPLTKAHEGKVAIAVKNLTSGETY-YHQAGLVMPTASLIKLGVMTAAYRLSD -QSEIRLNDMVLLQKEDKVPGSGILTSNFSEGFPLKDAIRLMIAYSDNTATNLVLDHI-GI -RTVNTTLTQMGFPNTRINAKVFKGSTQTKKYGLGSTTAKETIDLLELIYTNKAATEKSCT -AMIEHLKKCED-KDMIPRELTKLKSIAHKIGAVSD-ARTDAGIMYFDGG-PVVICVLTAE -NKTSENSAEILIGKIGLTVFDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543DNP5_9PSEU ---ELEREIRRTFADAGVHGRLHAVPLGGSREV-GVDPDEPVVMASVYKVPLLVAFCRAVD -AGGLDPRERVTVDPAERTAPSGLSVMRDPVTLSWRDLASSMITVSDNTAADVVLRRV-GL -AAVHEVLQDLDLAHTRVQGGTADVHRAYDPALDSATTARDMTRLLAAIWGDRAASPRRCA -FARDLLGAQVW-SHRLRSGFPVGVRVAGKTGTLG-AVRNEVGVVEFDGERPVAVAVFTRA -ARAELPRADAVIGQAARLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Fictibacillus solisalsi TaxID=459525 RepID=A0A1H0AB32_9BACI ---ELKNRLNGIIDPLTGEFAYYIET--EEGYI-GENEEKVFPAASLIKLPILIEAFRQKE -AGLLDLSLPVPIKPKDKVGGAGIINHLSPDALTVLDVLTLMITVSDNTGANVMIEQA-GR -ERINALLTALRCHRTVLKRKLMDFK-AIQEGKNNYTSAKDVVLLLKEIHHGKLMKNESRV -MMLDILRNQQF-RHKLPGSMDEEVMIANKTGELQ-GTEHDAGIFEYKDTT-VIAAVLTKN -LSNEAEARHK-LAAIGTAI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. RU2C TaxID=1907304 RepID=A0A1N6XAC1_9BACI --------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGRIIS--- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A521NA06_9BACT --kKLQAQLTELVKGFRGNLGLYVHDLTRNREV-AIRADSLFPTASMVKVPILTGLMRKIE -SGELQYHQPLVYKDSLLYEGEDILGSFKNGEIEMSKVMMLMLTMSDNTASLWLQTLAGTG -TAINRLMDSLGLVNTKVNSRTPGRENYRSEFGWGQTTPREMATLLEKIVKKEVISEAASE -KMLRLLGRNYW-DEEAISQIPSDVFIASKSGAVN-ASRSEVLYVNGKKA-RYLFCICTKN -NQNSSNEAWELTRKISRLLWEYy ->[subseq from] serine hydrolase n=2 Tax=Deinococcus wulumuqiensis TaxID=980427 RepID=UPI000346526A -------------ADYTGEVGLLVTDFGGRELY-ACAANAPFPSASTIKLPLLLMALEQAG -RGDLDLAERVTLRAEDRVPGAGVLHELSPGLLTWQDVLTLMIVVSDNTATNLLIERL-GQ -DDFNAWLTARGLNSTRLQQPPERQNAAQRRGERNRTSARDQVALLLSLLRGDGLTPQMQQ -LGLDILGRQQV-RDLIGRGIPAGYRVASKSGELR-GVHHDVGLLWTP--RPLVVALLSQG -GED--PREHPANRDVTRLAA--- ->[subseq from] serine hydrolase n=1 Tax=Nocardia cyriacigeorgica TaxID=135487 RepID=UPI0013C80B86 ---EITDRIRAVFADAGCTGWLHARRCGSPAEI-SVDAHDRVVIASVYKLVLLVAFCRRVD -AGLIDPRAPLTVYPADCTPPTGIAALHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEELLTELGLTETRIVGGTADVHRAYDPSYASATTPEEMTRFLDLIWAGGVLSPEQTG -FVRAVMGKQVW-PHRIASAFPRGVGVAGKTGTVGV-IRNEVAVVEFPDEYPVAVAVFTRA -ARADLAVVDAAIAEAARVAVT-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381UZQ6_9ZZZZ ---DLASRIEASLNSLNAKTSFYAKHLPSGREI-AIRADEPMNALSVIKIPIMVLAYRDAD -AGTLELDERYQIQPEDMRRGSGLLQSFSPGIPTYRDIITQMIITSDNTATDVVIKRL-GL -ERVNTMLAEMGFDQTRLRATTGELFRGDSTQWLGRITAREISHMLEAIEENELASPESSD -EMIGILRRQFY-SSRLPQQLRGRASIAHKTGDWPPHAGNDAGILYYEGG-PTVVAVFTNQ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Bacillus massiliogabonensis TaxID=1871011 RepID=UPI000C837297 ---ELKDNVYTEASKCRGRVGLIIEA--EDKRI-EINSEGKFSSASLIKVPILIECFRQAE -RGTLNLQQSIQIASVEKVGGAGVLQALSKDLLKVMDAMTLMIIVSDNLATNLLIDLI-GM -DQINQGMRELNLQHTELNRKMMDFT-ALTNGIDNYTTASDMLTCLKEIGQNRILSKESAS -KVKEIMENQQF-QNKLSDQIDDAFKVANKTGELF-GIEHDCAIIEYEKK-SVYAAVLIDQ -LRAP-KDGRQTLSSIGQLISQ-- ->[subseq from] serine hydrolase n=1 Tax=Filimonas lacunae TaxID=477680 RepID=UPI0012432BA7 ---KLEKQLRAEMAKYPARFGFAFKDLGTEQTF-LLNEKLAFHAASTMKTPVLMEAYKQAA -EGRFSIHDKIRVTNSSIVDGSSFSYQMVGKELAISDILHRMITKSSNLATNIIIDLV-GA -KNVMETMKGLGANDIQVLRGVEDQK-AYDAGKNNTTTAYDLMLLFEQLGNGNFINKMASA -EMIRILQDQHF-REIIAGKLPEEVRTATKSGSITK-IAHDSGLVFLPDGRKYVVVLLSSG -FDK-HEEAVNVLSGMSKMIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Firmicutes bacterium CAG:145 TaxID=1263005 RepID=R6FKV9_9FIRM ------ERLRELISPLKGKIGFYYENMIDGDKL-SYNADHVFTAASVIKVPLFMYVAKLVS -EGKLSWDQKVIVREGDKKPSCGALLSLSGDIVDIESLCRLMITLSDNTATNMLIRTV-GI -DELKRGFAQMGLVKTQIQRELFDDEAA-AKGLENYISPEEIAMLLKQVYQRGFVSRQVSE -KIENVMLLQQI-RHKIPGYIGRKKKIANKTGEDSD-TTHDAAIVFAQ--RPFVLVITSND -TD--VPQTERFIREAALELY--- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SG8_23 TaxID=1703356 RepID=A0A0S7Z965_9BACT --nRLQSDLEAVVHEYEGVAGLHVVDLTTGDRF-AVRDNLLFPQASAIKVPILLELFRRAE -SDPGLLRKRIEMTDEVRTGGSGVLHVLTDGGLSLEDYAIYMIQHSDNTATNVLIDEL-GM -EAVNALSASLGATRTLLQRKMIRPEES-ARGNENLSTPRDAARIMERIAACDLMSEASCA -RVREILELGKGG--PIRAPVPPSVPIAFKPGGIT-GVSTVWGLVGLPDR-PYVIVVMSNY -GG----NGGAVIEAVSGATYDYf ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus soli Cha et al. 2016 TaxID=1309411 RepID=A0A0F7JV60_9DEIO ------------ASGFAGTVGLRVTDVTGAELI-AWNAERVFPAASTIKVPLLVLALQEAQ -AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIARL-GV -DAVNAWLAAQGLTGTRLVGKLQQRNEAQRRGERNATTARDQTALLRALVAGDVLDEAHTA -LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVGLLSEG ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=UPI001290E672 --tKLEQKIRALTQNFQGDIGIYVKNLKTQKSV-LIQADSIFPTASIVKIPILVGVFDKIE -KGELNLDQKFTYRSSQQYGGSGLMQFFKDSTTDLSTLVGLMISYSDNVTSIWNQQLAGGG -LVINELMNKLGLVNTKVNSRTEGRHDIWKKYGWGQTTPREMATLVEMIYQGKVVSLKASD -RMYRYLGNIFY-NERSLSQIPAYIKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKHNEAEELTRKISHLLWNYf ->[subseq from] Uncharacterized protein n=2 Tax=Selenomonas TaxID=970 RepID=C4V1H1_9FIRM --eALGEAIEALSRADSTRYSVYADYPQENRQP-YIYQSESMRSASMIKVFILGTAMEQVR -DGRLSLAQTLTLRAADKVGGAGVLSGYADGSLSLDTVLRLMITESDNTATNMMIDLL-GM -EEINAYITRNGYTDTILQRKMMDTQAAAE-GWENYTSVSDLGRFFRRLYDHACVSTELDE -RMLDYLKGQTD-TECFPAALP-YAVIAHKTGELV-GLYDDGGIIYADGHD-VILVVMTEN -YS-GRERAIRTIRRMAQCAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7PYS5_9BACT -----------------------ARDPVSGFLL-EVNPDLRFHAASTMKVPVLIELARRVD -AGEVRWTDSIPVKNRSLADGSPFSYAAIGARWSLRQLATRMIVRSSNLATNLLIERL-DA -ARVTAGIRRLGADSMVVLRGVEDGKA-FAKGLNNTTTARDLATLLLAIEDRRAVSAASTR -EILAMLLAQEF-NDGIPAGLPPGTRVAHKTGEIT-ATWHDAALVYPPDGRPYALVVLTRG -IPER-GRGVGLHADVA------- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=A0A5D4TGI6_9BACI ----LKERVQAVIDSTAGHVSFVIDD-GNGQRL-GKDADVTKKAASLIKIPIMMAAFKQVE -AGRLNLSDRYSIDTRKIVSGAGVIQFMESDTFTLGELLTLMIIVSDNTATNQVIDII-GW -NVVDDFCREQGLTNTKLERKMMDFKAA-EAGLENRTSAHEMVECLKLLYVEDVFSDKSRQ -KMLRILGGQQL-LDKLPFYMDESVGIANKTGELP-GVEHDCGIVTYKGK-KLFVAVLIDE -LV-DNSIGKRAIQEIGKVVEE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Acidovorax wautersii TaxID=1177982 RepID=A0A1I2FBP4_9BURK ------------------------------------------------------------- -----------------------------------------------------------GP -RRVQALARALGMPESQLQRTMDEAYARFYRRGDNTAPLVDYGAMLERLVRGQLVNAQHQQ -QLYKDLKFDTYDAYRLEAGLPRTVRFIHKTGTQFQ-RACHMGVIDPQDGRRAIIVATCAE -GLDEQKQAGRAFEALGRAITQ-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. DH-12 TaxID=2072509 RepID=A0A2K2RJA4_9ACTN -----VARIHAAFADAGVTGRLHALDIDSGEEL-DAGADQPVCTASVHKLCLLVALHERAA -RGALDLAEQVETVPGGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTGRLGLTRTRAVHSFGEMLAALDPDRTNRSTPRDMTRLLRAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI000695CD02 ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALAALLGVPRSQLKASLQAVFDDYYASGRNAATLPAFARLLERLVAGELLSESSTA -LLLGHMREIGTGGRRIQAGLPADADFAQKTGTQQQ-RACNVGILDPDRGDGATVVVACAE -DFGELAQAEQAFQALGRALAQ-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=A0A5N7ILY4_9CLOT -----------YLSDAKLKYSIYIKELNQGEIC-EINQFEIVPSASIIKLFIMGSTLERVS -AGTLSLKDRITINKKEKVPFSILTLLDDDNSYTINDLILLMVIQSDNTATNKLIDII-GF -DSINDFIKKHNFNSSTLQRKMMDNES-RLKGIDNLCNISDCALFLELIYNGKLINEEYSK -LMVSILTHQLD-DSMMKINLPTNITIAHKTGDLDF-LKHDVGIVYTSKT-NYIFSMFTWE -AI-SDNYAKNLIGNISQITYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Woeseia oceani TaxID=1548547 RepID=A0A193LJD0_9GAMM --nKFQQGIERIADDLPGVLGVAVVDIDGNRVF-GVNESEIFPQGSAIKISILTAMYVRQE -RGEMDLTRSVPIRKADRVGGSGYLTHFSDGDLSLHDLAILMITVSDNMATNILIEQT-GM -DNVNAVMADLGFGDIRLQRRMIRQEQS-ARGNENIATPTSAAKLMQRILRCDLISGEACA -EMQAILAIRHAG--PIQAGTPNGIRVLQKTGSIA-GVATSWGVVDLEGR-PYALAMMGNY -GD--TAEINDSIRQITEL----- ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A651GVV1_9BACT ----LKSDIESYLSGQDGTFAVWFQHLDNPDLHfAINEDTLFHAASTMKTPVMIELFRRAE -QGEFDLSDSIKVENRSIVDGSEFQERMEDEMATIYDLNHAMITYSSNIATNLIIQLV-GA -EETTQTMRELGAEHIEVIRGLYDMKA-FDQGLSNRTTAKDLGIIFERIAKGTAVSPEKDT -MMIDVLKDQFY-RDVIPARLPDDVVVANKTGFIT-GVIHDSGIVYLPDGQSYILIFLSKD -LPEN-RIGTETGVAVSEMIY--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A5D4S1X4_9BACI --kDLREDLMKIVHECPGSVSFTILS--NDESL-SWEENRRISSASLIKLPIMMAAFEQIQ -TGSLKGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLTLMITVSDNTATNRLIELI-GK -DSINRFCLSWKLKRTFLNRKMMDFRL-LEMGQDNWTSSMDVVSCLRGINEGRF-EEASRR -KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDE -LQVP-EDGRRAISRIGKLVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter sp. 24 TaxID=2183986 RepID=A0A4R6FYT4_9FLAO ---ELQSKLENLIKDFKGDVGVYVRHLKTGKEV-AINADTVFPTASIVKVPILIKIFDKIE -KGELRYTDSLLYTKERIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -EAINELMAEIGLEKTRVNSRTKNRDKDWEKYGWGQTTPREMASILVKIRKRELISARASE -EMYRLLGNSFY-QEYALSQIPPYVQAAAKQGMVNT-SRSELFLVNAPSGD-YVCYIATKN -NQEDDNQAWQLQRDISALLWDYy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 4F TaxID=1751294 RepID=UPI000AC13FEB -----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE -RGALDLTEQVESVPEGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. GDMCC 1.1288 TaxID=2282649 RepID=A0A3E1Y789_9BACT ---VLQKKLEETVSQFKGFAGIYVCQLSTGRFA-AINADTVFPTASIVKIPLLVGLFDKID -KGELQYHQPMLYRDSIRYGGSGIMQFFKDSTTELSVLAALMMSYSDNTSSLWNQDLAGGG -ATVNKLMEQYGLKDTRVNSRTPGREAIRKIYGWGQTTPREMAALLVKIRRGEVVSPKASD -RMYRLMTKGYY-DEQAVAQIPAYIQVAAKTGSVDD-SKSEVLLVNAPHGD-YVLYVGTKD -IQTDDNEAVMLIRSISALVWKHf ->[subseq from] serine hydrolase n=1 Tax=Flavisolibacter sp. X7X TaxID=2364882 RepID=UPI000EAFC42D --kKLQRQMEELIRGFGGNIGVYVKNLKNGKTV-AIDADSVFPTASMVKIPILVGIMDKLN -RGELDYHQTLTYKDSLLYEGVDILGSFKSDEIELSKVMMLMLTMSDNTASLWLQSLAGKG -TRINEILDSLGFIHTRVNSRTPGRETARSVYGWGQTSPREMATVMEKISNGEIINPERSA -RMLRLLGRNYW-DEQAVSQIPSDVFVASKNGAVDE-SRGEVMFVNGH-GARYVFCVCTKN -NKTENNEAWVLTRKLSKLVWERf ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SWJ0_9BACT --sELENRIDSLLNSKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMLPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIRRLGIDSFNLSETEDDMHSSFEAVYRNWSTPSAMARLLRTADEKELFSNKEKD -FLWQTMI----------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SMS_SU21 TaxID=2069440 RepID=A0A2U2EXF5_9ACTN -----VARIHAAFTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACSPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] hypothetical protein n=1 Tax=Nitrincola alkalilacustris TaxID=1571224 RepID=UPI00124D92D6 ---DLITQVAALAANEGIEIGFAARLVESGQQI-SLNERQLYPSASVFKVPVMLEVLRRID -RGELRADQRLPLTTAAKTLTTGVLLTLDDGLLTLQDLMTLMIIISDNTATTMLLDLV-GK -DAVNQALHTLGCHDTTVTMNVHEMFLFARKRENTVTTAADMAHLMAMIAAGQAFGPQVSE -QAHLIMRQTQT-TGRVPRFLPY-RSVGNKTGTFR-GLRNDCGIITRADHDHIAYALFTFD -PTR-------------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridiales bacterium Marseille-P2846 TaxID=1852363 RepID=UPI000C83D1D2 -------EIKEALRALPGSISYYYEDLITGAVE-TFEAERPQVAASVIKLPILVEAMRQID -AGEANPDERFIVTGEQKMPSCGALSYHDGLAVTLTDLATLMIILSDNTATNLLIDRL-GM -ENVNRTAGALGLEQTCLRRRLFDAEAS-ARGIENTVSARDMGRLLSGMYRGQVASEHASA -AMLKMLANQRL-NGKLPFYLHAGIPVAHKTGEDS-GITHDVGIVYA--GRPFVVCILTSG -TD--VARAERTMQDVALALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A147GQG3_9BURK --rQLAERIARIDQQTPGRLGVYVKRLSDGSTM-NHGTEQAWYLASMAKVPVALAVLRQVQ -VGKAGLGDEMALQDGDRIDVGNIVWNDTGTRYSVRTLVERMLLESDNTAANMLIRSV-GE -DALNDGTRQMGTPNVTLTTFAQVRRDRYYRRNLNTATLQAYGGMLERLVRGQLLPEEPRT -VLYKAMKRDIYTGYRLQAGLPRDMPFIHKTGTQHR-RACHAGVLNPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAIR--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilales bacterium HUM_18 TaxID=1916231 RepID=A0A292S2M7_9BACT ----LKSQLEGLMAQYPIKPAIYVWEYENGKFV-DINGDSLYSAASIIKLPVLIRLFKSIE -AKQMTIYDDMLLTDYYQSPGSGNLQYAQTGRYSLDQLAKTMIQDSDNTSTNMIMAKLGGM -DDINAGLRDWGISKTYVRTWLPDLTGT------NKTTAKDMAKLLYNLDNPGFLNINSRE -YIIDYMSHVKN-NRLIAADLGDGALFVHKTGDIGT-MLGDAGIVYAQNGKKYIVVILANR -PH-NAPQGKDFIVKASSLIYK-- ->[subseq from] serine hydrolase n=1 Tax=Salinicola sp. CR57 TaxID=1949086 RepID=UPI000DA134D2 ------------ERTGTGEIGVHVRRLDDGERA-GWRDAERWYWASLVKVPVAVELLDRIS -RDGADLDDTMTLHASDYVDGAGATNWAAPDTIPLRTLLERMLIDSDNTATDMLMRRV-GL -EAVNRRARSLMDEGIGPITTLIDVRRRYYATGLNSGRLDRYADMLERIDEGEALPAAATA -TLLSIMQRADTGHRRLAAGFQRPWPFAQKTGTQYS-RFCDAGILAPGTPGAVVIVSCLRG -AP-SRREAERTFQAIGRAV---- ->[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI000E683C34 --------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNQYGRRLIADLGRIIS--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus indicus TaxID=246786 RepID=UPI00068A828E ---------AGILSNCPGRAGACFSW--NGEWL-EAGSSDVFSSASLIKLPVLLTAFRLAE -KGNLDLNEKVKLRDVEKTGGAGVLQALSEDALSVQDLLTLMITVSDNAATNWVIEKI-GM -PKINETIEGLGLVNTKLNRKMMDLD-AIQSGMDNFTSPADMVRCLQAISEGDFVSEDSRQ -KILDILQKQQF-TDKLPYSMDKDLIAGNKTGELP-GIEHDCAIIKYRDT-SVYAAVMIDQ -LEQ-KEWGRKTISEVGNLIYEK- ->[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013C764CB -----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Terrabacteria group bacterium ANGP1 TaxID=2569760 RepID=A0A537L3C6_9BACT ----VVQDIERLAGRFSGVLGVWSHSLTSGEMV-EWNAQDVFPAASAIKLPILYEVYRQAG -EERFRLTDTRTVEAADVVPGSGVLKDLTPPVLPVRDLAMLMIVVSDNTAANLMIDLV-GI -DAINRSMQALGLTATVMEYKF---FHAPPSSRGARSTPADLGCLMTQIADHKVLTPGACE -EMLGILRRQHYTD-YVTRRIPEYITVASKSGSIR-GTRNDVALVEGRDC-RYVIAMMSRD -CKDRDNEAAVLLADVSALIYGYf ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudorhodoferax soli TaxID=545864 RepID=A0A368XNE1_9BURK ------------------------------------------------------------- ------------------------------------------------------------P -QRAEAVRRALALPAGALRTDIDTAYADYYAEGHNSATLAGYGAMLERLVRGELLSPASTD -RLFKAMKFGTRGSYRLEAGLPKSLPLIHKTGTQHR-RACHVGVVQPQDGDATVLAVCAAD -LD-EQRAAGRLFEAVGRAIA--- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A161T698_9BACI ----LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ -TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM -DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK -KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTYE -LPAP-EEGRRVIRTMGKLIGD-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura kijaniata TaxID=46161 RepID=UPI00082F0E58 -------RVEEAFRDAGVTGWLHAVDLDSGREV-SVRGDEPVVLASVYKVPVLVAFHRQAA -AGLLDRTAPVTLRPDGRTAPTGISAMLDEVRMSLRDLALLMMTVSDNAAADAVLARV-GL -DAVNKAMADLGLSRTHIAYDGRDLHAVLDPARTTRSTPREMTRLLAMVWNDEAAPPEDCA -QMRRMMGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-LRNEIGVVEYPDGGRYAVAVFTRS -PLAVLPQADAVIGTAARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI00099B4E3B --------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLSVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGQIIS--- ->[subseq from] serine hydrolase n=1 Tax=Angelakisella massiliensis TaxID=1871018 RepID=UPI0008F91C9F --dELERQAAALVEANPAHICALCIPLGEEPLF-DLGGKTRVVSASTIKTPILCTALEQVR -EGKLSLDQPVKVDREVILEDSEFFDLGPG-TFPLWELLYWMIVTSDNTCTNVLIDLL-GM -DTINAWCAAHGLENSRVERKMLDWK-AIEEGRNNYTSPWDQYKLFAALYRREILTPELCG -TAWEILLRQRSTDQFL-RYISDDVQVAHKTGGLDY-LNHDCGIFCLPEH-PYYLGVFVSN -AP-KIEGDNRVVGQLSRLAYDY- ->[subseq from] Beta-lactamase n=2 Tax=Intestinimonas butyriciproducens TaxID=1297617 RepID=A0A0S2W053_9FIRM ---------EARLSAIPGHIGFYYQNLDTGEVQ-TFHALDRFQAASVIKLPILAAVFLHEQ -ECPGILSRRILVRDSEKLPGCGALQHIAGDHYDVLSLCRLMITLSDNTATNALIRHF-GI -DTLNEDFSRLGLEDTRLYRLLFDAEAA-SRGKENLFQPRECGLLLERLYRGTCVSSAASE -RMLAILLQQQI-NHKIPGRLPAEFPVAHKTGEDT-GITNDLGIVYG--NSPFILAFASNE -TDV--PAFEQTIR---------- ->[subseq from] Beta-lactamase CARB-6 n=1 Tax=Bacteroidetes bacterium ADurb.BinA245 TaxID=1852818 RepID=A0A1V5GGH9_9BACT --kQLQSKIEQAISGFQGEIGIYVKNLRTGKTV-NIHADTIFPTASIVKVPIMTGIVYKMN -KGELHYDSLFTYKDSLLYEGEDILGSFKSGEIALKKLLMLMLTTSDNTASLWLQTIAGGG -ANINRILDSLGFKDTRVNSRVPGREAFRAIYQWGQTTPKEMGQLFEMIYNRKLFSSDLCD -RMMRMLAKNYWDENEAISQIPPTIAVFSKNGCVNK-TRNEAMIVNAPKN-PYVFCIFTKN -NKTHENEAWTMARKVSKLLWGYf ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia puris TaxID=208602 RepID=A0A366DHT4_9NOCA ----TVDRIRAVFADAGCTGWLHARRCGTAADI-SVGGLDRVVTASVYKLVLLLAFCRRVD -AGLIDPRARLTVHPADCTPPTGIAALHDSVTVSRRDLATSMMTVSDNAAADILLGEI-GL -GAVEELLTELGLTETRIVGGTADVHRAYDPSYTSATTPEEMTRLLDLAWGGGVLSAEQTD -FVRSVMRKQVW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLSAVDAAIAESARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. v-76 TaxID=1761769 RepID=A0A1C4EXZ5_9BACI --------VRQWSSMYRGRVSYLFET--PEERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDIQAS-AEGRDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGRIIS--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 143-6 TaxID=2485999 RepID=UPI000F79D69C ----------STIGQMSGVNSVYVSPADSSKTV--IENNQSQRSASSIKVFIMAAAYQMAE -AGTFDMSGVYTVQASDKVGGTGVLQSMANGTLTNQELIRHMIIDSDNMAANVIIDRLGGL -DAVNQEIEDLGATDTSLNRKLMDQD-ALNAGRDNMTSVKDLGMVMKRIYNQKLISKDADQ -NMLAILAQNNN-HTKLPAKLPATIKVYNKTGEYDYGVQNDAAVFETNKGA-LVVVVLSQD -GEHDEQ--LAT------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=UPI0009E91F7B --rQLAERIARIDQQTPGRLGVYVKRLSDGSTM-NHGTEQAWYLASMAKVPVALAVLRQVQ -VGKAGLGDEMALQDGDRIDVGNIVWNDTGTRYSVRTLVERMLLESDNTAANMLIRSV-GE -DALNDGTRQMGTPNVTLTTFAQVRRDRYYRRNLNTATLQAYGGMLERLVRGQLLPEEPRT -VLYKAMKRDIYTGYRLQAGLPRDMPFIHKTGTQHR-RACHAGVLNPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAIR--- ->[subseq from] Beta-lactamase class A n=1 Tax=Aquisalimonas asiatica TaxID=406100 RepID=A0A1H8PZ54_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -----AFLDKIGAGASEADSLEEAFG-RYYETGLNSGPLTGFGAMLERLWEGELLNEDHTG -RLMAQMEQVTTGDRRIRAGLPDGTPYAQKTGTQIN-RACDVGIIHPEDPERTTIVAACAE -DYGDLRHAEEAFQALGRLLAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium faecium TaxID=34087 RepID=A0A2T5YB45_9SPHI --tKLEQKLRALTQNFQGDIGIYVKNLKTQKSV-LIQADSIFPTASIVKIPILVGVFDKIE -KGELNLDQKFTYRSSQQYGGSGLMQFFKDSTTDLSTLVGLMISYSDNVTSIWNQQLAGGG -LVINELMDKLGLVNTKVNSRTEGRHDIWKKYGWGQTTPREMATLVEMIYQGKVVSLKASD -RMYRYLGNIFY-NERSLSQIPAYIKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKHNEAEELTRKISHLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenaceae bacterium 429 TaxID=2562948 RepID=A0A4S1EAS8_9BURK ---QLESSLTPLLEKEPARISMAVRTLDGVSLF-DWHVQRAMPSASLIKVPMLLCLLEEVA -KGRVSLDDVRALPDSNRAGGTGILSQLPGVQLSLRELAHLMIVLSDNVATNALIDVL-GM -DRINQWCRQAGLAYTELQRHMMDAQAR-AQGKDNWTSAADACTTLLYLLQSPVLPEALRQ -EGLQMLADQRE-RGHFAAILPADVELAHKTGSLP-GLRHDAGIMTVGKR-SVVLAVLADG -FT-DARTSS-------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 2BBP-J2 TaxID=2719381 RepID=UPI00142FD0B3 -----VARIHAALADAGVTGWLHALDVDSGEQL-DAGADQPVCTASVHKLCLLVTLHEQAA -RGALDLAEQVEAAPEGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHTFGEMLAALDPARSNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase TEM n=3 Tax=root TaxID=1 RepID=A0A0F6IVF0_BACTU ------------------------------------------------------------- ------------------------------------------------------------- -------MHNMGDHVTRLDRWEPELNEAIPNDERDTTMPVAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter chitinilyticus TaxID=2233776 RepID=A0A443Z0N4_9SPHI ---KLNKRIGELVKGFNGEVGVYVKSLKTGKIA-TYNADTIFPTASMIKVPITCGVFDKIE -KGELAYNTQLIYKDSLLYAGEDILGSFKSGEIWLAKVLMLMITTSDNTASLWCQSLAGTG -TAINALMAKYGLEHTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIREGKMISEAASE -RIYRNLIRIYY-DKEALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCIITKN -QKDTDNEAEVLIRKTSKMLWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Chloracidobacterium thermophilum (strain B) TaxID=981222 RepID=G2LLF7_CHLTF ----MMRRLQRRLAAFKGKVFCFAKNLDTGETF-GYNPDARVRTASTIKVPIMVEVFAQVA -EGRLRWDDKLTVVRRHEYEGGVLFELTPGTQITVRDAVRLMIVVSDNIATNILLDRI-TT -DAVNDRLAKMGFEHIRSLRKIAGGGEENKKYGIGVATPREMVRLLEGLERGTMVSPEASR -EMLAIMKRQQY-REGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKHG-RIAMAITVED -IPCSEAEGHLLIADI-------- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga rhizosphaerae TaxID=1864947 RepID=UPI000F80AF28 --rKLTAQLLELTRSFNGDVGIYVQHLKTGRFA-AINADTVFPTASIVKVPLLVGLFDKID -KGELSYHQPMVYRDSAKYGGSGLMKLFKDSATEISVMAALMMSYSDNTTSLWIQSLAGGG -QRVNEILEQYGFKNTRVNSRTPGRADIWKIYGWGQTTPREMTRLVSMIRKGEILTPAACD -RMYRLMCRGYN-DESSLSQIPPYVQAAHKTGAVDD-ARGEVVLVNAPHGD-YVFQIATKN -IKDQDNEAVVLIRNVSAAIWRHf ->[subseq from] Beta-lactamase class A n=2 Tax=Thermomonosporaceae TaxID=2012 RepID=A0A2P6ULD3_9ACTN ------ERIEAAFRDAGVTGYLHALDVDSGREI-GLRSDEPVVLASVFKVPLLVTFFRHVA -AGRLDPAAQVTLRPEDRCAPTGVSALQDEVRMSLRDLACMMITISDNAAADALFAAV-GL -DAIDATVAELGLRATRVVGTGRDLHEALDPMRTSRSTPREMARLMAMIWRDEAAPPAECA -QMRRFFGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS -PLAVLPQADAVIGTSARLAVE-- ->[subseq from] Beta-lactamase, beta-lactamase n=1 Tax=uncultured Gemmatimonadetes bacterium Rifle_16ft_4_minimus_1650 TaxID=1665094 RepID=A0A0H4T164_9BACT --dKLRADLEAIAEDFDGVLGAQIVDLTDSTTV-GVNQRLVFPQGSAIKIPILIEVFRQAE -RRPGMLQERRPVTRAAQVGGSGVIQYFGDGSLSLEDLAVLMITLSDNTATNVLIDAV-GM -NAINQTLADMGFRETRLQRKMIQPEAS-LRGEENLSTPAEAAEVMTRLARCDLVGQASCR -RITEILEIPKG--GAVREPVPGSVRIAFKPGTLE-GVATVWAYVELPDR-PYVVVVMTNY -GG----NGDEAIRMVSEVAYGYf ->[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus hopiensis KR-140 TaxID=695939 RepID=A0A1W1V818_9DEIO -------------RGYAGTVGVLIQDLAGRELY-TLNPERVFPAASTIKVPLLILALQEAQ -AGRLDLQARVLLRAEDRVPGAGVLHELSPGLLTWGDVLTLMIVVSDNTATNLLIGQL-GV -DRVNAWLGDRGLAQTRLVGRLERQNEAQRQGERNRTSARDQVALLGALMRGELLDGAHTE -QAQSILSRQQL-RDLLGRNVPRDYRVASKSGELR-GVHHDVGVLFTP--HPLVVAVLSEG -GL--------------------- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI0013908578 ---KLRSELNSIAAAQHGRWAFAVRE-GGGLVA-SVNGDEVMRAASTIKVALLILALQDVE -AGQCRLDSELDVPE-ERAGGSGVLKLMRSVRLPLREVLELMIGVSDNCATNIVVDLL-GL -DHISARINALGARSTRLERRLMDLEAA-RSGRDNVTTADDQALLLDLLTGTQLLSEDARR -LALDILGRQQF-NDRMPARLGPDIVCRHKTGELS-GVRHDVGILEFDGR-QVVLAALSSE -LADPTGVAADVIGAAAQAVV--- ->[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI000A523293 -----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE -RGALDLTEQVESVPEGRTAPTGMAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=UPI000BA91544 ----LDAQVRQIAEDAGASVAVAVRDLETGEAA-TVDGDRPFHAASTMKVAVLAALLAAVA -DERHHLDDRLHVRNRFRSAGSPFRFAKRGRTMPLGTLAEHMIQTSSNLATNLLVDLL-GV -EAIREATARWGGAGVEVVRGVED-EAAYEAGIVNTATAYGLVGLFVGLEEGAGLPDEVRQ -FGLDVLFGQEF-ASGIPAGVPEGSRFAHKTGSIST-VQHDAGLVYLPDRRPYAVAILTEW -EADATNGRRETVASLSRAVYDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea pusilla TaxID=46177 RepID=A0A1H8F7I3_9ACTN ---------REIFDAAGARGFVHARDVDADAET-GLDPDEPVVLASVFKIPIALEYARQAA -AGELDRTERLTVTAADKDGGIGVSGCADDVSLTLRDLAHLMLTLSDNAATDVLLRRV-GL -ERVQATLAGLGLTRTRLIGGCAELFDVRDPERTTSATPRETTTLLSMIWRDEAGPAEACA -EVRAIMSRQVW-PHRLASGFGDEVKVSGKTGTLW-GVRNEAAVVEYPDGKRYAVAVFVRT -AAFRHPAADAAIGRAARVAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A522T9W0_9BACT ----LQSRLEAITRTYPGHVALYAKNLRTGAVV-AIDANRPVPTASVIKVSLMLEAFRQVK -AVRLSLAQPLTLTKANQVEGSGILRILTPGELSLRDTIALMMTLSDNTATNMVIDAV-GL -KPTNAFLAQIGMKNTYFYKKVFMPAAPQPADQKGKTTAREMGEMLERIYRCDLGNRSLCR -EMINIMRDQQD-REMIPRYLDDASPIADKVGELD-AVRNDVALVYTRSGQ-VVISMFTYN -NPTPDNKAELFIGRVAQTIVHAw ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381TNF1_9ZZZZ --kQLETILKDKITSFDGVAGLAVKSLTGEKSI-SINGDEVFPTASTIKIPVLAKLFSLQE -EGEIDLSKRIRFTQDMYGAGSGVIHFLENDPFTVLDVAILMMLASDNTATNTCIDIA-GI -EGVNDLIRDMGLSKTKLRRKMMDPE-AINRGDENVSTPNELIMLMDHLHNRKP-TPKVSA -QVLGIMSKPKS--AYLNKAIGSKVVVANKPGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF -SMVDSIAQEGFLIDLARTIH--- ->[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. SA29-B TaxID=2695856 RepID=UPI00132A551F ----LNHLLEAELSRWPAHTGLYVKHLGTGEQA-RIRAQEHFESASTIKVAIMVRAFQLAD -ENKLDLTSRHELTAGDYRGGSGILKYDLGLKLTLHDMITQMIITSDNTATDIMVAKVGGR -EKLNEFLREAGYKALKLNRTTHEFF----------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. SA29-B TaxID=2695856 RepID=UPI00132A551F ------------------------------------------------------------- ------------------------------------------------------------- --AFTEPYRELIAQVTTAEERARESRARHNDDETGVATPAEMGALLEGIERCTLATRQSCE -DMKRILRAQQV-THKIPHYLS--VPAGNKTGDTGS-VTNDVGIIYSLSG-PIVMASYNMD -IKAQRTELDDRIGALARRVVDYf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0012EE81F3 ------------------------------------------------------------- -----------------------------------------SMAYSDNTANNKIIKEIGGI -KKVKQRLKGLGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVSKDCKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus similis DSM 23365 = JCM 2765 TaxID=1423804 RepID=A0A0R2FG50_9LACO --------VNQTVGNIAGTNSVYVSPVNGQQNV--LTVNRSQSAASSIKLFILITAYAMEK -AGTINLNDSYTLTASDKVGGTGVIQNMADGTLTYRDILRHMIVDSDNTGANIMIDKLGGF -DPINAKIKSLGDTGTKLKRMMMDTD-ALDNGIDNMTSARDMGTTLKRLYNHQLVSKKADS -EMLSILVANND-HDKLPQNLPSTAKVYNKTGEYDYGIQNDAAIIENTHGA-FVVVVLSEN -GHRD--EQISAMNQLGEQLY--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium symbiosum TaxID=1512 RepID=UPI000E539DB0 ----LKLNVLNLCSRIEGKKAIVIEDLKTGEAV-EINRDEVFPAASLIKVPVLSALFRMAK -ENHIALDERIELEKDSRIGGFGILKDLGDGLPAVRDLAVLMITLSDNIAANLLIDRI-GM -SQINSELQAMGMKHTVLQRKMMDSQAK-ERGLDNYTSAGDMQKLMKAILESSF-----RG -DILDILFRQQC-NNKLPALMEGGVRFAHKTGDLP-GVEHDAGIICTDDRE--IIAIVLTD -ELADNREGIWLNQEIGKLI---- ->[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A316Q2S9_9FIRM -----QKHLEELIKPLKGKIGFYYENMTDGGTL-TYNSSEVFTAASVIKVPLFMYIAKLVN -EGKLSWDQQVIVRDEDKKPSCGALLSLSGDIVDIESLCRLMITLSDNTATNMLIRAA-GM -ENLRKGFKDMGLSKTEIQRELFDDS-ASAAGLDNYICPEEIAMLLKEVYRREFVSPDISE -KIESVMLLQQI-RHKIPGYIGRKKKIANKTGEDSN-TTHDAAIVFAQ--KPFVLVITSND -TD--VAETERFIRQVALELY--- ->[subseq from] serine hydrolase n=1 Tax=Fischerella thermalis TaxID=372787 RepID=UPI000CC03A8D --------------------------------------------------PILVALFEEVD -AGRIKLNETLVMRRDLMTGGSGTLQKRPGTKLSVLETATKMITISDNTATNMIIDRLGGK -AKLNQRFRSWGLQNTVIRNLLGDFKGT------NTTSAKDLVRLGALLANNQLLSDTSRS -KTLDIMRRVEN-RSLLPAGLGKGAVIAHKTGTLGI-ILGDAGIIQTSTGKRYLAGIMVRR -PFGD-KRAKSFINQVSRLVYSY- ->[subseq from] hypothetical protein n=1 Tax=unclassified Bacteroides TaxID=2646097 RepID=UPI000AF4D17E -----------------------------NDSIsGVNQNERFAMHSVMKFPQALYVADYLS -RKGLALDDTIVVDKADLMQWSPMLKRFEGKKFSYAELLELSLAQSDNNACELLFRHCGKP -KAVEKYMRKLGFYDIYVRITEEKMHKHSSKAIENSSTPAEIARLFEWFYHHKD-DNQYLT -FIWKTMADCSTGLKRIPAAIPAGAHIVHKTGTGFLQDMNDAGLIIMPDGSHAIIAVFTKQ -SP-----SEAVITDIARQL---- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=U5L843_9BACI --nQLEKRLADILRQCPGNASLAVEY--GERAI-YMNSGRKYPAASLIKIPIMMEAFFQAE -EGVLDLSEQVCIGGIEKAGGAGIIQSLSVTALSILDCITLMIIVSDNTAANLLIKLL-GK -KNINDRMHGLGLQTTVLGRKMMDFEAA-AKGIDNFTTAADMVKCLRAIKDGELFSEKNRS -KMLDIMEAQQF-REKLPALACKELKIANKTGELP-GIEHDCAIFAS-GRDVLYAAVLIEG -LS-SPEEGNHAIRLIG------- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=UPI000CCC42CD ---EIEKRLGEIIGEAEGTWGVVVEELGGGQHF-SHMPDERFIAESVIKVPIMAAVYEAAD -NGQFSVSDQLTLRKEDLVGGSGFLYTLSPGLLTIRDLITMMIIQSDNTATNMLIDLV-GK -EQIEQTMRNLGMNQSRYSRKLMIYPV--DVTENNMITAGDVASMLGKIASGAFLSQRACE -EMIAIMDKQQV-VNGLPSLLPPEWKLPCKSGWDT-GRQHDVGVLIAAGRK-ITITALSKD -VQAS--AALRTLGLLGKAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7Q176_9BACT ---TLRNRLEARIARAPAQVGVYYRSLVRPDSV-LIGANLRLHAASTMKVPVMIQIFRDAD -AALLGLDDSLTVHTASLVPGAAFTYALVGRNRSVRELLELMITRSSNLATNILIERV-SA -SRAQASARSLGAWSTQVLRGVEDGA-AYRAGLNNTTTARDLGVLLGAIAGGLAASRAACD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAGVVYPADGASYVLVVLTGG -IKED-SVAHNLVADLSRLVY--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus similis TaxID=414682 RepID=UPI00138EF77E ---------------------------------------RSQSAASSIKLFILITAYAMEK -AGTINLNDSYTLTASDKVGGTGVIQNMADGTLTYRDILRHMIVDSDNTGANIMIDKLGGF -DPINAKIKSLGDTGTKLKRMMMDTD-ALDNGIDNMTSARDMGTTLKRLYNHQLVSKKADS -EMLSILVANND-HDKLPQNLPSTAKVYNKTGEYDYGIQNDAAIIENTHGA-FVVVVLSEN -GHRD--EQISAMNQLGEQLY--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces uncialis TaxID=1048205 RepID=A0A1Q4V8M2_9ACTN -----RSRIRSVFTDAGVTGWMHALDLGDGAEV-AVAADTPVSTASVHKLCLAVTVQRFAD -EGRLDLDEQLESLPGDRTPGPTGLSMLSGPVMSVRDLLAMALTVSDNAAADLLIDRV-GL -DAVNDAMRALGLRRTVAVQTMRDLIAVLDPARANRSTPREMTRLLAALWRDEACSAGRAR -ELRAVLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-VRNEAGVVEYPDGGRYAVAVFTRS -ARARQPAADAAIGTAARLAVR-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=UPI000A3A25EF -----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharomonospora xinjiangensis XJ-54 TaxID=882086 RepID=I0V623_9PSEU -------------ETTGVRAWVHARCLATGRQA-GYRAGERVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRVTAGDRLGGTGTAGCSDDVELSLRDAAFLAMSLSDNSAADLLFDRV-GV -ENVQALMTELGLTSTRVVCPPRDVVRALDAKHTNASTPEDMTRLLELVWTDKAGRPESCA -AVRAWMAQQVN-WLRLGAAFPPEVSVEGKTGTLPC-VRNEIGVVTYPDGGRYAVAVFTRV -ASGRRPDIERAIGLTARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Cytophagia bacterium TaxID=2026730 RepID=A0A2E0H0N4_9BACT ---SLDIKIKKMLKSQEGTFAVAFKNLDDGSKI-LINENEEFHAASTMKTPVMIEVFKKHL -NGEVSLDDSILVKNESIVDGSIFKYKMIGKYISLRELVYDMITISSNFATNLVVDYI-GA -GSINNSMREIGANRINVLRGVGDLKA-FDLGLNNTITAKDLLIIYENLANGKIINKNLSE -EMVNILKNQKY-SDIIPKYLPKNLEVAHKDGWIT-GVRHDSGIIFLDNEKKYILILLSKN -LD-DEVKGADLLANVSLEIYNH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces violens TaxID=66377 RepID=UPI0004BF5E39 -----ERTIREMFADAGVRGWLHVAELDRSAQV-TIDPDEAVPMGSVYKVPLMVAFCRLAD -AGELDPRERLTLEPPDRVAPTGISILRDAVTMSLRDLVVMMMSVSDNTAADALLRTV-GT -AAVDEVCRDLDMPDTRIHGGVAGTWDVYNPLSKAASTPADMARLLRAIWTGRAASPERCA -FMREVMGRQPW-RHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELPDGSTYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus puniceus TaxID=1182568 RepID=A0A172TC09_9DEIO --------------GFAGVVGVRVCDEAGQELF-SLNADRVFPAASTIKIPLLIMALQAAQ -RGEWALSERVTMEAADRVPGAGILHELGAGLLTWQDILTLMIVVSDNTATNLVIERL-GV -DAVNAWLNTAGFPLTRLVGKLDQRNEAQRRGERNRTTAQDQTELLGRLLRGDYLNSTHTD -LALSILSRQQY-RDLIGRRVPCGYRTASKSGELG-GVHHDVGVLWTP--RPLVLALLSEG -GL--------------------- ->[subseq from] TLA family class A extended-spectrum beta-lactamase (Fragment) n=1 Tax=Ignavibacteriales bacterium TaxID=2049428 RepID=A0A3N5QAM3_9BACT ------------------------------------------------------------- -----------------------------------------TVSHSDNNGCDILFRLIGGT -GKVEKYIQSLGIKDISISTTEEEMHKDWDTQFTNWSTPYAMGLLLMKFFKGEILSKNSQE -YLWEKMVNTTTGANRIIALLPEGTIVAHKTGSSSTAATNDAGIVKLSDGNYFAIVVFVSD -SKSNVKAREGIIAQISKAVWDYy ->[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2E3BQD9_9CHLR --eQLENTLKDKITGFNGVAGLAVKSLTGEKSI-SINGDEVFPTASTIKIHVLAKLFSLQE -EGEIDLSARIRFTRNMYGAGSGVIHFLENDPFTVLDVAILMMLASDNTATNACIDIA-GM -EGVNDLIRDMGLSXTKLRRKMMDPE-AINXGDXNVSTPNELITMMDHLHNQKP-SPKVSA -QVLRIMSKPKS--AYLNKAIGSTVVVANKXGGMDK-VRGDTGIVYLPNN-PYAVSIMSKF -SMVDSIAQEGFLIDLARTIH--- ->[subseq from] Uncharacterized protein n=2 Tax=Mucilaginibacter polytrichastri TaxID=1302689 RepID=A0A1Q5ZSI8_9SPHI --kKLTAKLQEAVSGFQGEYGIYVHHLKTGKTV-SLNADTIFPTASMIKTGIQCAVMDKIE -KGELQYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVAMLMITMSDNTASLWLQKLV-GG -EYINNWLAQNGFKVFRVNSRTPGRQEQQKQYGWGMSTPYEMCRLFTMIHEGKAVSEAASE -RMYRNLIRIYW-DENALSQIPPYVQAASKQGAVNQ-ARSETVLVNAPHGD-YVFSVMTNN -IKTPDNEADQMIKKISALLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Sphaerisporangium sp. LHW63015 TaxID=2248750 RepID=A0A366LU32_9ACTN -------------RAAGVTGWLHAADIDTGAQV-GFGAHAAVPIASVFKLPLLVAFVRQAD -AGLLVPAERVAVPAAERVFPTGISAMLDDVTVTLRDLCYLMIAVSDNTAADVLLARV-GI -DAVNAMLDDLGLTATRVLHDCRETAAVLDPASTNRSTPAELTRLLAMVWRDEAASAESCA -FVRRLLGLQVW-PHRLSSGFPDDVSVSGKTGTLPT-LRAEAGVVEYPDGGRYAVAVFTRS -HALNQPRADAVIGTAARMAIDH- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P4200 TaxID=2040295 RepID=UPI000F6428A0 -------DLQSLINDLKGTCGLYIKDLQNNEEY-SFNKDVIFPSASIIKLFIMYKLFENLE -KGIMSLNDKITLKECYKVGGFGILKNLDENLLTLKDLVTLMITLSDNTATNMLIDLL-GM -ETINEDI----LSSTCLQRKMMDST-ALKKGLDNFTSPMDVCTVLEKILYTDSISETNKK -IMLDILKKQQC-NNKLPVNISNKLQLAHKTGDLP-GVEHDAGILFYKNQA-FIIVVLTKD -LEN-NTHGVQFNNKIGRLL---- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces griseorubens TaxID=66897 RepID=A0A656RI89_9ACTN -----VARIRAALTDAGVTGWLHALDIDSGEQL-DAGGDQPVCTASVHKLCLLVALHEQAE -RGALDLTEQVESVPEGRTAPTGMAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYALAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Nitrospirae bacterium TaxID=2026887 RepID=A0A533ZPN4_9BACT -----ERLIRHRLSALDARVGLHALHVPTGRQV-AVNADEPMNTASVIKIPIMILAYRDAE -AGSLHLDERYEVTLDNYRRGSGLIQTFTPGLPTIRDLVRQMIVTSDNIGTDIALGRV-GL -MRVNEMLTQFGYQQTRINKSTGDLVRREPAEWLGQSTAREMSRLLLQLLRGELASAATTE -EMLDILRGQFY-DSRLPRFIKEQALVAHKTGEAPPYVINDTGIIFHEGG-PTVVTVFVNQ -NQGTVLEVEEVIGQIAKDLVSAw ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A522PPI6_9BACT ------RQLGAIASRFGGKVTFAAVDLKTGERY-GLAADQPVATASVIKLPVMVEAFFQIQ -EGKLQWSQPVKETDFDRVQGSGILQDLNPQILTLGDAITLMIDLSDNTATNMVIRTV-GI -EPVNVRMRMLGLRHTALNGYVDATNEEAKKFGLGVTTADDMVHLLTLIKQHEILTPAACD -QMLKILGKQRDIDARYTSGLP-GVTWEHKTGALD-AVRNDVGIADTPAG-PVVMAGFAFD -SPHQWTADNAVLGRLAQAALQHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0009E65255 ----LREEMMGIVQECSGKVSFSVLL--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ -TGRLRADAMIVLRHEDHVEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM -DSINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EESSRK -KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTYE -LPAP-EEGRRVIRTMGKLIGD-- ->[subseq from] serine hydrolase n=1 Tax=Thermoactinospora rubra TaxID=1088767 RepID=UPI000A0FD5B2 --------------------WLHAVDLDTGAEV-GHGADRPVVLASVFKLPLLVEFARQAD -AGALDWTEPVTVGPGERVFGPTGLSAMLDEALSLRDLAYLMIAVSDNTAADALLRRV-GL -DAVNAMLDRFGLERTRLVGGAADLFRVLDPARTSRGTPRECTRLLALIWRDQAASPERCA -WMRSVLGLQVW-PHRLASGFPDDVEVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -FSVNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Nocardia puris TaxID=208602 RepID=UPI0011BEF108 ----TVDRIRAVFADAGCTGWLHARRCGTAADI-SVGGLDRVVTASVYKLVLLLAFCRRVD -AGLIDPRARLTVHPADCTPPTGIAALHDSVTVSRRDLATSMMTVSDNAAADILLGEI-GL -GAVEELLTELGLTETRIVGGTADVHRAYDPSYTSATTPEEMTRLLDLAWGGGVLSAEQTD -FVRSVMRKQVW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLSAVDAAIAESARIAVT-- ->[subseq from] ClassA_beta_lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WL65_9BACT --qTLDERINDAVKDFKGKVWIYAKNLDTQKTF-SLRGDERVRTASTIKLPIMVETYFQIS -EGKLKWTDEIILTKEKKVGGSGILGEFSDNTIDLRTAVNLMIVVSDNTATNLVLEKV-TS -DAVNARMESLGFNDTKSIRRIFGSEKIIKNFGLGMSSPKDMVGILEMLELGQLVNSEASK -SMLHVLKRQQY-KDGIGRNALDTVPVASKSGTLDR-LRADVGIVYTRRG-RIAMAITVDD -MQ--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Gelidibacter gilvus TaxID=59602 RepID=A0A4Q0XL62_9FLAO --kNLEKGLQNLVKDFEGDVGIYVYNLKTNQEA-GVNADTIFPTASVVKVPILIEVFNQIK -AGKLHLKDTLVYDAKRKYGGSGLMQFYKDSTTDLRTLASLMITVSDNTTSLWCQELVGGG -MEINKTMADLGLAHTRVNSRTEGRTKDWETYGWGQTTPREMASLLVKMRNRTLVDAASSD -EMYRIMSNSYYTDYSL-SQIPPYVQTAAKQGMVNK-SRSELVMVNAPSGD-YVFYIATKN -NADEDNKAWQLQRAISAYLWQYf ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4Y005_9ACTN -------DFESLFRRAGVTGWLYAADIDTGREV-GLDPDEPLPTASMYKVPLLVAFRRQVD -AGLLDPARRVTVPASDRLAGTGIAAMQDDVTISLRDLAYLMISVSDNTSADTLLELV-GC -DTINAMLDRFGLTGTRVVQSWREGSAVLDPARSNCATPRELATLFAMIWRDEAASAESCA -WMRGMLNLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRAESGVVEYPDGGRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=A0A385LC87_RHORH ------------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPQEMTRLLEAVWSGSVLSPESTD -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A419ZHV4_9NOCA ------------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A0Q3TF67_9BACI --dELREKVYTEASRCKGRVGLIIEA--EDKRI-EINSEGRFSSASLIKVPILVECFRQSG -KGTLDLQQSIQIALVEKVGGAGVLQALSGNLLKIIDLMTLMIIVSDNLATNLLIDLL-GM -DQINQGMKELNLHQTELNRKMMDFT-ALNNGVDNYTTASDMLTCLKEICQNKILSNESAS -KAKEIMENQQF-NNKLSDQIDDIFKVANKTGELL-GIEHDCAIIQYENRN-VYAAVLIDQ -LTVP-KDGRQTLSSIGQLI---- ->[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium RIFOXYA12_FULL_61_11 TaxID=1797896 RepID=A0A1F9MHN9_9DELT ---QLQRRIALVSREFPGEVGLLVKDLTSGQVY-ATNAHTPFYLASTTKICVLVTLHHEIQ -LGRLTLEQKHVVQRDDFRDGSSAFEKLSPGSLSIAELQEMMMNDSDNAATDILYNLL-GA -ETINRVVRRLGFEQVGWITSMLEVRKRFYASSYNTATLWEIGRFLEAMYRGEILGREIDG -QMLALMRGCRTGKRRLEAGFPQGVLFAHKTGTQYR-CLCDLGIAELTDGPTLFLGAYVRG -YKETRTKAEEILARLGAAVIESf ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7M5V4_9BACT ----LRDRLEARISRAPAQVGLYYRNLAGSDSI-LIGANLRLHAASTMKVPVMIQIFRDAD -AGLLRLDDSLTVHTASLVGGGAFTYALVGRNRSVRELLELMITRSSNIATNILIERV-GA -SRAQASARALGAWSIQVLRGVEDGA-AYGAGLNNTTTARDLGVLLGAIATGRAASRGACD -SMLAILGRQEF-NEGIPVGVPPGTRVAHKTGWIGEVVYHDAALVYPSAGVGYVLVVLTGG -IKED-SVGHNLVADLSRLVYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Streptosporangiaceae bacterium YIM 75507 TaxID=2339229 RepID=A0A3A4B918_9ACTN -------------REAGVTGQVHAVDVLGGRDL-GVGADEDAVLASVFKVPLLVAFARLAD -AGALDPRERVHVPAEGRSPPTGISAMLDPVDMSLRDLAFLMITVSDNTAADTLVGRV-GL -DAVNAAMRELGLRRTHVEHTGQDMYAVLDPAVTNRGTPREMTRLLELVWRDEAASPESCA -MIRRCMGLQVW-PHRLASGFPDDVMVSGKTGTLPT-IRNEIGVVEYPDGGTYAVAVFTRS -SSQTQPRADAVIGVAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 311R TaxID=1617904 RepID=UPI00067EC5A2 ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEQATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLFERV-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVAVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI00075144B3 ------------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLTRLGLTRTRIVGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSALSPESTA -FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea maritima TaxID=683260 RepID=A0A1G9RUQ0_9ACTN -------ELEEVFTSAGLRGLVHVREVDGDAEI-GLDPDEPVVLASVFKIAVALEYARQVA -AGELSRTERLTVTAADKDGGIGTSGCRDDVSLTLRDLAHFMLTMSDNAATDVLLRRV-GL -DRVNGTLAALGLRRTRLIGGCAELFDAVRDPARTTATPREITTLLAGIWRDEAGPPEACA -EVRRIMGEQIW-PHRLSAGFPDEVRVSGKTGSLW-GVRNEAGVVEYPDGRRYAVAVFVRS -EVERLPHADAAIARAARLAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A317ISL2_9BACT --kELQKEIESLVQGFNGKVGIYVLNLKTGKVA-AFNADSIFPTASMVKIPILIGVMDKIS -KGELKYHDEIVYKDSLLYSGVDILGSFKSDEIELSKVMMLMLTMSDNTASLWLQSLAGNG -LRINQILDSLGFKITRVNSRTPGREEARNEYGWGQSSPREMVELMRKIYKGEIIDRNYSA -RMLRLLGRNYW-DEAGISQVPPDIFVASKNGAVDE-SRSETMFVAAPHE-PYIFSIMTNN -NKQPGNEAWVLTRKLSQLLWNKf ->[subseq from] serine hydrolase n=1 Tax=Escherichia coli TaxID=562 RepID=UPI00119DDEFD ------------------------------------------------------------- ------------------------------------------------------------- ---------HMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. E(2018) TaxID=2502239 RepID=UPI0010FA0C62 ---QNEQALLKLISSGEGTYGVSIYHFETKESF-EHHSDELFYSASIIKVPIMAAVFAHAA -EGKCSLSDKIPVREEDIVPGDGIIKHLSPGMWTIHDLIVLMIIESDNTATNVLIDLL-GI -DQINTYMKEWGFDQSHLHHKLQ-IKAAREPGKMNVLTAHEINEFLKKIALGSVVSLYSCK -KMIDILKQQKM-NDLLPSLLPPNWEFAHKTGYVS-------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Saprospirales bacterium TaxID=2026790 RepID=A0A3C2EG45_9BACT ---------RALLSDDQGVFAVAYRDLDEPDRMvFINEHEVFHAASTMKTPVLYEVFRQAK -QGRFNIHDSIIVKNESIVDSSVFSKEKVGRKATIYELCFEMITKSSNLATNVIIDLV-GA -KNVTNAMREIGANDLQVLRGVEDLKA-FELGLSNTTTAIDLLVLFEALEKDKLPDPESSS -EILKILRSQFY-RDIIPRYLPREVVVANKTGSITQ-VMHDSGLVFLPDGRKYGLVLLSKK -WTDEA-KTREKMAQISKMIYESy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. F-7 TaxID=573566 RepID=UPI000A8B1D83 -----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVTLHEQAA -RGALDLAEQVEAVPEGRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHTFGEMLAALDPARSNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. BUPNP1 TaxID=1432786 RepID=A0A225TMR2_9NOCA -------------------------------ML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPQEMTRLLEAVWSGSVLSPESTD -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A4Y4I1T9_9BACL ---ELENRLSAIIRQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRKEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIDQTMIDLGMRQSYYSRKLMIYPLD--IAENNKITAGDVASMLGHLATGSYLSQRACQ -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKN -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Lentzea kentuckyensis TaxID=360086 RepID=UPI000A383D96 ---------TEVFAEAGAEGFVHAREIGTDHEF-SFGADDPVVLASVFKIPVAVAYAEEVA -AGRLDPAERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVLFHRV-GQ -AAVDKVLSNLGLHRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAVPEACE -RVRQIMTQQIW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGRAYAVAVFTRA -KSLDQPAVDAVIGRAGRLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535GIF5_9CHLR ---------RALIERAPFRVGVFARSADADTLL-EHDPDQALPSASVIKVPLVMTLYADAA -DGRIDLERRMRLG--DRVDGSGVLRDLRDVALSLRDLAALTMILSDNTATNLVIDAV-GV -ERVAERLAEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD -AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVFRGPERT-VLVAAFTSH -VE-DHLAAEHLLGILGR------ ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Sphingobacterium sp. TaxID=341027 RepID=A0A3D5A6N8_9SPHI ----LQQYINQIITGKNALVGVAISGISQNDTV-GVQASQRLPMQSVFKFPLAIVMLTEID -KGNFTLDQKIEITKRDLTPWSPIRDKYPDGVLTLREILEYTITLSDNIGCDVMLKLLGGP -QKVEQYFAKQGFKNISIKINEKTMQSNWDKQFLNWCTPQEMNNILKIFYVNNLLSMSMYD -FLWSTMKSTNTGL----------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535YL67_9CHLR ---------RALIERAPFRVGVFARSADAETLL-EHDPDQALPSASVIKVPLVMTLYADAA -DGRIDLERRMRLG--DRVDGSGVLRDLRDVALSLRDLAALTMILSDNTATNLVIDAV-GV -ERVAERLAEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD -AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVFRGPERT-VLVAAFTSH -VE-DHLAAEHLLGILGR------ ->[subseq from] hypothetical protein n=1 Tax=Vaginisenegalia massiliensis TaxID=2058294 RepID=UPI000F549A64 -------------------------------------GDQAIRSASVIKLFILADLFKQAE -KGEVKLDQVYKLKAEDKVGGTGIQNAAPGTTFTYRVLATEMITNSDNTAANILINQLGGI -EEINRYIQSLGFTQSKMERKMLDTQ-ALNAGKDNYLSAKEVGEFLEKLYTKQLVSPQADQ -AMLDILLLQID-HGKLTNQLPSGTPIYSKSGQFEYGVVNDAAIIETDKGA-YIMVVLSQD -GNYDA--KVSSLQQLGKAIHEAf ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga eiseniae TaxID=634771 RepID=A0A1T4SZQ0_9BACT ---RLQQDLQQIVAKFQGTAGVYVQQLQTGAWA-AINADTLFPTASIVKIPLLVGLFDKLE -KGELGYHQTLIYRNSAKIGGSGLMQFFKDSSTEVSILAALMMAYSDNTTSLWNQQLAGGG -AAVNVLLEKYGLKDTRVNSRTPGREENRKIYGWGQTTPREMATLLAKIFRGEVISRASSE -RMYRLMTKGYY-DEQALTQIPPYVQAAAKTGSVNE-SRSEVVLVNAPHGD-YVFYIGTKN -IKDQENEAVNMIREISALLWKHf ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. SGR-19 TaxID=2710886 RepID=UPI0013ECF5DA ---RLERMLKNEIKDFQGDVGIFVQHFKKNRTV-SIQADTIFPTASVVKVPILVGVFDKIN -HGKLKLNDSYIYDAKRIYGGSGLMQFYKDSATNLSTMVSLMLTYSDNVTSIWCQELAGGG -IAINQLMDELGLPNTKVNSRTEGRQKIWEKYGWGQTTPREIVKLMTMIEAGKVISPRLSD -KMYRYLKNQYYNG-EALSQLPAHIATASKTGALNQ-TRNEVVFVHAPSGD-FVFAILTKN -NKDQDNEAEVLIRKISNILWNYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8SEH7_9BACT ----LDRRVRDEAAKFEGTVSLYAKNLDTGAEY-SFGGDERVRTASTIKIAIMIEAFSRVA -EGRAKWTDELVLTKEKKVSGSGILPEFSDGLLTLRDAVTLMMLMSDNTATNLVIDALGGA -DTVNARMQSLGMTDTRLMRKVGGGGESEEGKKEGRTSPHEMVMLVEKWERGEIVSPSVSK -EMIEFMKREQVQDGIWRELWK--TPRATKSGALD-ALRSNVGIIYHTRG-RIALAVTCDD -MPEPN------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Xenorhabdus ishibashii TaxID=1034471 RepID=A0A2D0KA77_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- ----TRFARTIGDNFFRLDRHEPELNTAIPGDERDTSTPQAMAKSLYNLVLGDALVKTQRE -QLAEWIKGNTTGGASIRAGVPKDWIVGDKTGRCDYGTTNDIAVIWPPNRAPLVLVAYFTQ -PDKEAGSRPDVLAAAARIVTQ-- ->[subseq from] serine hydrolase n=1 Tax=Aminipila sp. CBA3637 TaxID=2697030 RepID=UPI0013678351 ------------INTIPGHIGFYYKNMVTDECI-SFNENHHYIPASVIKLPIVMEIFRLSA -KGKVSLDSKLLVKDEDKMPSCGALNSFTGELVDIRTLCNLMITISDNTATNVLISYF-GT -DTLNEGFQSIGLTETRVNRRLFDAEA-SEKGIQNVITPAEIGMLLERLYRNEFVNQQVSE -DIKEILFRQQI-KHKIKELLPVGTKVGSKTGDDDN-ISNDVGIVYAK--QPFVVCFISNE -T---------------------- ->[subseq from] serine hydrolase n=1 Tax=Atopobium vaginae TaxID=82135 RepID=UPI00065DEEEF --kELQQQIEELTQPYGSSVSVCIIDASNGNYC-HVNSDKAFVSASMIKLAVLCEYMHAVD -NGQLDPADRVTLKNMKVVGGTGLIQTERHASYSYDELCRYMIMYSDNTATNVLINKL-GQ -DAINERVQALVCKNTSLNRQLMALNTN----TENWISARDAATILYKFKNGTAASSTICA -KALEYLSKQTD-NEGMAEGISSG-AFAHKTGSLRS-MRHDGGIVL--GKRPYVIVALCDI -GAGN---ANRLMKEIAQKA---- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535I8I0_9CHLR ---------RALIERAPFRVGVFARSADAETLL-EHDPDQALPSASVIKVPLVMTLYADAA -DGRIDLERRMRLG--DRVDGSGVLRDLRDVALSLRDLAALTMILSDNTATNLVIDAV-GV -ERVAERLVEWGCRKTALRRRMYDFEAA-KRGLENVATARELASLLAILVEGRCRDRSTSD -AVLAVMERCAD-DTMLRRFLAPGTMVPSKSGTLD-ASRNDVAVIRGPERT-VLVAAFTSH -VE-DHLAAEHLLGILGR------ ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Shigella sonnei TaxID=624 RepID=A0A2Z6A9V3_SHISO ------------------------------------------------------------- --------------------------------------------MSDNTDANLLLRTIGGP -KELTAFLHNMGDHVTRLDRWEPELNEAIRSDARDTTMPAEMATTLRKLLTGELLTLDSRQ -QLRGWTEADKVAGPLLRSARPAAWFIADKSGAGERGSRGTIAALGPDGKPSRIVGIYTTG -SQAT------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Z38 TaxID=2682780 RepID=UPI0012EA58FD -----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -EAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Rhodothermus marinus TaxID=29549 RepID=UPI001374DA27 --------FGRIEHRYELTLGVAAYNLTTGASV-FYRADTLFPTASVIKLAVLVELYRQYE -QGYLSPQDTVVLTAGRIYPGSGVLQHLSVPRLSLQDAAVLMIILSDNTATNLVFDRL-GP -DSVNATLRSLGLQRTRMLNKPFGFSTNTPEARRGMGTPRELMQLMIAMARDRVVSAEASR -EMIEILKRQQW-TEMAPRLLPDTLQVAHKTGAIST-ARCDVGLIFSPRD-TIAFAVMTDH -IKDPDQVGNLAVAEAARLVYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia tenerifensis TaxID=228006 RepID=A0A318KF22_9NOCA ---------------------------ETAAEI-CVDGHARVVTASVYKLPLFVAFCRFVD -AGRIDPTARLTVHPADCTPPTGLAALRDPVTLSRRDLAQSMMTVSDNAAADVLLGEV-GL -AAVDELLTELGLTETRVVGGTADMHDAYDPSYASATTPEEMTHFLRAVWTGAVLSSEQTE -YVKTVMRHQVW-PHRIAAAFPHGVSVAGKTGTIGV-IRNEVAVVEFPGEHPVAVAVFTRA -ARPHLPVVDAAIAEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodothermus marinus TaxID=29549 RepID=A0A5S9CAP4_RHOMR --------FGRIEHRYELTLGVAAYNLTTGASV-FYRADTLFPTASVIKLAVLVELYRQYE -QGYLSPQDTVVLTAGRIYPGSGVLQHLSVPRLSLQDAAVLMIILSDNTATNLVFDRL-GP -DSVNATLRSLGLQRTRMLNKPFGFSTNTPEARRGMGTPRELMQLMIAMARDRVVSAEASR -EMIEILKRQQW-TEMAPRLLPDTLQVAHKTGAIST-ARCDVGLIFSPRD-TIAFAVMTDH -IKDPDQVGNLAVAEAARLVYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7V6A9_9BACT ---SLASRVSERLKRCDAVMGVAAKSLASGEAV-LVDADRRFPTASAIKTAVMVEVFHQIA -EGRFDRDKEVVLTREEKVDGSGVLQDHAGLRLTVGDLLSLMISVSDNTATNLLVGLV-GT -ASVDRRLEGYGLVDTKLFRPTRDGKADHPELERGMSTPRELVRLMELIAEGRVVSRAACD -EMLALLRAQQF-RTMIPRRLPEGIKVGDKPGWDERHVRIDAGVVETPRT-RYVIAICARQ -VRDTDNDALVTGADVARLIHDHf ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Staphylococcus epidermidis (strain ATCC 12228) TaxID=176280 RepID=A0A6A1YIN1_STAES ------------------------------------------------------------- -------------NKDDIVAYSPILEKYVGKDITLKELIEASMTYSDNTANNKIIKEIGGI -KKVKQHLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKN -FLLDLMFNNKNGDTLIKDGVPKDYKVADKSGQATYASRNDV------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora sp. ASAGF58 TaxID=2719023 RepID=UPI00144010C0 -------------DGLPGRAGFAAWDLDEQEPV-LVDAERVVHAASTIKVLIMIAALRAVQ -DGRIELDEYVELPA-ERVGGFGILRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF -EAIRDCAADLGCTATRVERRLMDPNAH----GRNETTALDQARVLDALARGTALPPELTE -HALEVLSKQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGA-DRPRAVVAVLVDE -LTDER------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. HNS054 TaxID=1662446 RepID=UPI000ABD66A5 -----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -QAVNATTERLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4Z1H9_9PSEU --------------GLPGRIGFAAWDLDEREPV-LVDAERVVHAASTIKVLIMITALRAVH -EGRLGLDAEVELPAE-RAGGFGVLRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF -EAIRACAADLGCTATRVQRRLMDVNAP----GRNETTALDQARVLAALAEGSALPPELTE -HALDVLSRQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGD-ARPRAVVAVLVDE -LTDER------------------ ->[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI000D6166AC -----VARIHAAFTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus cohnii TaxID=29382 RepID=UPI000FECF340 ------------------------------------------------------------- --------------------------------MTLKDLIKASMLQSDNTANNKIMEELGGV -KGFKHELKQLGDNISNPQRLEPELNLYDPNSTADTTTPRAAAQTLNTILTSDQINDGNLD -LLKQVMIENETGDSLIKAGVPDNYIVGDKSGQGTYATRNDLAFIYPDKHKPIILAIYTKQ -DDKDGQPDDKVIADATEEAI--- ->[subseq from] Beta-lactamase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=A0A0F0H6W5_LENAE --------IADVFAEAGAEGFVHAREIGTDNEF-CHHADDPVVLASVFKIPVAVAYAEEVA -AGRLVETERTKVTSQYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRI-GQ -EAVDKVLKNLDLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLEAIWTDRAAAPEACE -QVRRIMAQQIW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGRSYAVAVFTRA -KALDQPAVDAVIGRAGRLAVDH- ->[subseq from] Putative beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67QS8_SYMTH ----LEEALHAYVSALSGTYGVAVVDLSTGATV-SVGGDQVFVAASTFKVPLAMYVFSLVE -RGEADLAEPLYYAPEDWEGGSGILHGSIAGDYTVAELVHLSLTVSDNIATNMLLRRF-GE -QNVFAYMRELGGTVTNLSTGR------------RATTPRDMALYMEVAYRRAAGDDGGYR -TLLGLLTQTAF-SDRIAAGAPSGVSVAHKIGTLP-AMVHDVGIVFLQDR-PFAIALFSSG -VNES--VAAASLADITRLV---- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E7G4T3_9CHLR ------QDIDLIIKDVPAVVGVAARHIQSGKSF-FNKADEVFFTASTLKIPVIFELYRQVD -KGIVNPMQRIIVEDYDKSPGSGVLKDLTEGIPTIYDLATLMIIISDNTATDIIYKII-GK -DNIHSTLLNLNLKNTFIPMTCKELLYALAEDKSDVSSPNDMIKLMEIIYEKKILTEKSSN -IILDIMYRQQS-KTIIPYFLAPDIKTFHKTGGVTS-VRCDVGIVNGKSG-PYSIAIMAKD -VQ-DHKNIDLYLAKISEALYNFf ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J3 TaxID=903528 RepID=A0A1X7KE32_RHORH ------------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLTRLGLTRTRIVGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSALSPESTA -FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura umbrina TaxID=111806 RepID=A0A3D9SJ00_9ACTN --qRVRARIEEAFRDAGVTGRLAAVDVDGGRGI-GVRPDEPVVLASVMKVPLLVALHRQAA -AGTLDPAERVVLGPDDRTAGSTGLAMLRDEVMSLRDLAALMITVSDNAAADALFARV-GV -PAVNTVLAELGLRGTHVAGTCRELFDALDPARTSRSTPAETAGLFAAIWRDEVAPAAHCA -QMRRLFALQVW-PHRLASGFPDDVRVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS -VSAVLPKADAVIGTAARLAVEY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ETH9427 TaxID=2211357 RepID=UPI000E0BE34B -----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -EAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Asinibacterium sp. OR43 TaxID=1076522 RepID=UPI00047DE39C --qHLQQQITQLIAGFHGDIGIYVHDLKKNRTI-AINADTVFPTASMVKVPILTGIMDKIH -RKELDYHQVLIYKDSLLYEGVDILGSFKNNEIELSKVMMLMLTMSDNTASLWLQTLAGKG -TRINELMDSLGLKVTRVNSRTPGREANRNMYGWGQSSPREMASLMEMIVKKQVISDSSSQ -MMLRLLGRNYW-DENAISQIPSDAFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN -NKESTNEAWVLTRKLSKLLWEYy ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus sp. RL TaxID=1489678 RepID=A0A072N862_9DEIO -------------RGYGGEVGLLVTDLAGTELF-ALNADRSFPAASTIKVPLLVQALEEAQ -AGRLDLGARVCLQAEDRVPGSGVLHELDPGLLSWRDILTLMVVVSDNTATNLLLGRL-GL -GGANAWLRERGLSGTCLQQPPERQNAAQRRGERNRTTPRDQVRLLGQLARGELLDAPHTE -LALSILARQQF-RDLLGRHVPRDYRVASKSGELR-GVHHDVGLLLTP--RPLVVALLSEG -GTD-------------------- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522R9Q1_9BACT --kKLTKELEKTVAGFHGTIGVYVWNLKNGKGA-SINADTLFPTASTIKVPIMCALFDKIV -KEELSYHQPLLYRDSAAYGGSGIMQYFKDSTIDLSVAATLMITRSDNTAALWCQSLAGGG -TVINQWLADHGFQNTRDNSRTPGRQKIWEIYGWGQTTPKEIANLVVDIREAKVLDSAACE -RMYRNMTHQYW-DDIALSQIPPYVQTASKGGAVDD-ARSEVVLVNAPHGD-YVFAVYTKN -NKTPNNEAEVMIRKISALLWHYf ->[subseq from] Uncharacterized protein n=1 Tax=Lactobacillus rapi TaxID=481723 RepID=A0A512PPS0_9LACO ---KVTKAVRATVQQASGTTAVYVATSKLAT---GVAVNRRQRSASVIKVFIMIEAMRRVK -AGTLNLKQEVAIPAHDQVGGTGVLAQRGTNQQTIGQLLELMIKVSDNTATNVLIDQLGGL -SKINRTIENLGCHHTKLQRKMLDYR-ALNAGHDNYTSAADLGRTLLKIDRHQLLGGRYDT -EMLRLLANNAN-QTKLPALISSKATIYNKTGEFDYGVQNDAAIVKKGQQ-SFVAVVLSES -GRQN--QQIKAMN---------- ->[subseq from] Uncharacterized protein n=1 Tax=Halovibrio variabilis TaxID=31910 RepID=A0A511UJE1_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -----ALARTLGVSTASFTQDYDHAFDAYEATGENVGALSAYGDLLASLHDGRDLDALQRE -RLLAMMQRTRSGQQRLKAGLGDGISFAHKTGTQQR-RSCDAGIAQRESAGPWVIVACARG -PAA-VSAHERALAGVGDAI---- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7W7Y6_9BACT --------------------------------I-LRNERVTFHAASTMKVPVMFGVMQAVT -HGELRLDQPVRVKNDFVSIGSHYAYEMIGRELPLEELVRRMIDRSSNLATNIVIEFI-GA -PRIMELMKSIGANDIRVLRGVEDDK-AYHAGMNNTTTALDLMLIFRALGERTVISREASD -RMIEILLAQEH-NDGIPAGLPPGTRVAHKTGWIT-GITHDAGIVFRPDGSKYVLVVLTRG -FK-SEKQAKRVQARIARATW--- ->[subseq from] Serine hydrolase n=1 Tax=Flavisolibacter ginsenosidimutans TaxID=661481 RepID=A0A5B8ULM0_9BACT --kKLQKQVEELIKGFNGDVGVYVKNLKNNKTV-AVNADTVFPTASMVKIPILLGIMDKIN -RGELAYHQPLQYKDSLLYAGVDILGSFKNDEIELSKVMMLSLTTSDNTASLWLQSLAGGG -LRINQILDSLGFVNTRVNSRTAGREAIRNVYGWGQTSPREMATLMEEIVKGEIISKERSA -QMLRLLGRNYW-DEEAISQIPSDVFVADKNGAVNE-SRSEVLFVNGH-GARYIFCICTKN -NKESNNEAWVLTRKLSKLLWEYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BF231F --------LQDAFTEAGVTGRLHAVDIDSGAEV-GVGADQPVVTASVHKLCVLVTLHEQAA -AGRVDLTEQIECPPEGRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAELLLDRV-GL -DAVNATTARLGLTRTRAVHSFREMFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ARATLPSADAVIGTAARIAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Stigmatella erecta TaxID=83460 RepID=A0A1I0L3L6_9DELT ----LNGLVETAARNFDGELSLYVLDVESGEEY-AYDADRLTYLSSAIKLGVMLEVMHQVD -AGRLSWDEPLAFTSDSLRDMHRLHRARPGDALPVSALLEYMMVDSDNAAADLLMKRV-GV -DAVKAQLATRGVQTGPVVSLLDERRRAFYAEQVNSASMRGMGQLLRQVARCEGLSAASCT -RAHTLMRACQTGRGRVAAGLPATAAWAHKTGTQHR-RACDLGFLTLPSGQPAVIAACTRN -FWR-VADAERLFAFLGESVWR-- ->[subseq from] Uncharacterized protein n=1 Tax=Halobacillus mangrovi TaxID=402384 RepID=A0A1W5ZZE8_9BACI --dALQREVEHIVASVKGRVSVVIEN--KKAAI-AINGSERTTAASTIKIPIIMEAFRQAE -NGDLDLKEKVQVTPDLKTGGDGVLKLLENELLSILDLMKLMIVVSDNTASNLLITRL-GF -SNINHLCEQLGCTNTRLNLYFMDFRAR-GAGVDNMTSARDMVAFLSEIEGGNFVNERSRK -TIYNILREQQF-TSGLPAYNKEDILTANKPGMLP-GIQHDVGIFKYRNET-VYAAVLLSE -LN-DEEAGRRAITDIGRSIIK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter salegens TaxID=143223 RepID=A0A1M7NT09_9FLAO ---KLQQKLETIARDFKGDVGIYVKHLKSGKEA-AINADTIFPTASIVKIPILLKIFDKIE -KGELSYKDSLVYSKDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -EGINELMAEIGLEHTRVNSRTEGRDKDWEKHGWGQTTPREMASILEQIRNRKLISAAASD -EMYRLLGNSFY-QDYALSQVPPHVQAAAKQGMVNK-SRSELFMVNAPSGD-YVCYIATKN -NEEENNEAWQLQKEISALLWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4R150_9FIRM ---DLTAILERMTRGLPGTIGIYVTDLITGRSA-GLSPMAEFYAASTIKVPIAMAVLWLVD -RGRLSLDQTIAYQPEDYEAGTGILQARPGDQVSVRRLLELMITVSDNIARNMLERFI-GS -GTIRNYMLSLGVAPA-YDPHE------------TPVTPYGMNQVLLALDSGRGLSPASTR -MLLRWMEEAVF-RRRIPRYLPESVVAATKIGSRDD-EFHDIGLVYAPDR-SFAISVFTKG -MT--EARAEEAIARIAEAVYW-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. RL TaxID=1489678 RepID=UPI0009DD64D7 -------------RGYGGEVGLLVTDLAGTELF-ALNADRSFPAASTIKVPLLVQALEEAQ -AGRLDLGARVCLQAEDRVPGSGVLHELDPGLLSWRDILTLMVVVSDNTATNLLLGRL-GL -GGANAWLRERGLSGTCLQQPPERQNAAQRRGERNRTTPRDQVRLLGQLARGELLDAPHTE -LALSILARQQF-RDLLGRHVPRDYRVASKSGELR-GVHHDVGLLLTP--RPLVVALLSEG -GTD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A4P5TDK2_9BACT --eKLESKIKAEFKRSPGLFCLAFKEIGQPQNQlMIHADSIVHAASTMKTPVMVEIFNQIE -QKKWKLSDSILVKNESIVDGSPYKYQKIGGKTTLYQLIYDMITYSSNLATNILIEMA-DA -KKVTQKVREIGAKNMQVLRGVEDQK-AYDLGLNNQVTARDLMLIFEKLGEGKWISESSCI -QMIDILKQQHF-NELIPALLPKEVIVAHKTGWITK-HSHDSALIILPDGRKYALVILSKG -WE-SNDLATDILANSSKYVYDY- ->[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium ISCAR-4553 TaxID=2558931 RepID=UPI00141E987E ----LQARLERLVEGFRGDAGVYVRHLPTGRYA-AIHADTLFPTASLIKVPILIKTFDAIE -RGELAYQQELVYRDSLRYPGVDLLGSFKDGEIALSKMVMLMLTMSDNTASLWLQHLCGTG -TAINAWLAAHGFEHTRVNSRTPGREAARERYGWGQTTPREIAELLVMIREGRAVSPAASE -EMYRTLTRTYW-DDEALSQLPPTVQAASKQGAVSR-SRSEVALVNAPHGD-YVFAVITKN -QEDTDNEGFVLLRDVSRLLWEHf ->[subseq from] Beta-lactamase class A n=1 Tax=Lentzea albida TaxID=65499 RepID=A0A1H9DTK9_9PSEU ----------------GVEGFVHAREIGGGREF-CHGADDRVVLASVFKIAVAVAFADEVA -AGRLDASERTRVTSRYRIGGIGTAGCADDVEMSWRDLASFMMTMSDNAATDVLFHRV-GQ -AAVDAVLTKAGLERTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPQACE -EVREVMSRQVW-PHRLSSGFPSEVRVAAKTGTLPT-VRNEAGVVTYPDGRSYAVAVFTRS -SSPDDPAADAVIGRAGRLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus praedii TaxID=1742358 RepID=A0A4R1B101_9BACI ---ELKENVYTEASKCRGRVGLIIEA--EDKRI-EINSEGKFSSASLIKVPILIECFRQAD -RGTLNLQQPIQIASVEKSGGAGVLQALSSDLLKVMDVMTLMIIVSDNLATNLLIDLI-GM -DQINQGMRELNLQHTELNRKMMDFT-ALKNGLDNYTTASDMLTCLKEIGQNRILTKESAR -KARSIMENQQF-QNKLSDQIDDAFKIANKTGELF-GNEHDCAIIEYENK-SVYAAVLIDQ -LKVP-KDGRQTLASIGQLISQY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus depressus TaxID=1602942 RepID=UPI00124C9D90 ---SLKAKVEEVAAKCQGRVGLVVET--SEGRL-EIRHHEKFSSASLIKIPILIEGLRQYD -HGLLHLQEYVPASPSSRVGGAGVIQTLSDDLLKVVDLMALMIIVSDNTATNLLIDRL-GK -DKINQCIQALYLQSTELNRKMMDFV-AIRNGRNNYTSPEDMITCLKVIDNQQFLSGASSV -KALTILENQQF-KNKLSYLMDDHIRVANKTGELP-GVEHDCAIIKYGGK-TIYAAVLIDQ -LSK-QEDGHKTLAQIGKLVSQY- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium estertheticum subsp. estertheticum TaxID=1552 RepID=A0A1J0GFF8_9CLOT -----------YLSDAKLKYSIYIKELNQGKIC-EINQFKIVPSASIIKLFIMGSTLEKVS -TGTLSLKDRITINKKEKVPFSILTLLDDDNSYTINDLILLMIIQSDNTATNKLIDII-GF -GSINAFIKKHNFNSSTLQRKMMDNES-RLKGIDNLCNISDCALFLELIYNGKLINEEYSK -LMVSILTHQLD-DSMMKINLPTNITIAHKTGDLDF-SKHDVGIVYTSKT-DYIFSMFTWE -AI-SDNYAKNLIGNISQITYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E8X584_9CHLR --qQLEDTLRTKIDAFNGVAGVSVKSFNSGNSI-SINGDEIFPTASTIKIHILAKLFHLEE -QGEIDLSKRIRFTRDKYGSGSGIIHFLENDPFTILDVAILMMLASDNTATNTCIDIA-GI -EDINDLIRDMGLSETKLRRKMMDPD-AINRGDENISTPNELVLMMDHLHNEKP-SPRVAS -QVLRIMSKPKS--AYLNKAIGPELTVANKPGGMDK-VRGDTGIIYLPNT-PYAVSIMSKF -SMVNSLSQEGFIIDLAQTVHA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudogracilibacillus auburnensis TaxID=1494959 RepID=A0A2V3VXY8_9BACI --nELKERLEQLVKSEDGNWAIVVEDLDKQDSL-SINGKHQYYAASIIKLPIMATAFSMAD -QGLLCLSEKIKLKKVDVVGGAGVLQHSIGLELTFYDLLMLMIIQSDNTATNMVIDRL-GK -KQIQATMSQIGMLHSSFYNKLMTVPVQLEG--RNMITAHDVSTFYRTVVEGKFSSQYACE -QMIDLLKRQQI--QHLTAYFPPEWTFASKTGSVEN-LYHDTGVLYKRDRT-VIINVLSEG -CNQ--NKAIRMINQIGKEVYEY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus praedii TaxID=1742358 RepID=UPI00070FB2ED ---ELKENVYTEASKCRGRVGLIIEA--EDKRI-EINSEGKFSSASLIKVPILIECFRQAD -RGTLNLQQPIQIASVEKAGGAGVLQALSSDLLKVMDVMTLMIIVSDNLATNLLIDLI-GM -DQINQGMRELNLQHTELNRKMMDFT-ALKNGLDNYTTASDMLTCLKEIGQNRILTKESAR -KARSIMENQQF-QNKLSDQIDDAFKIANKTGELF-GNEHDCAIIEYENK-SVYAAVLIDQ -LKVP-KDGRQTLASIGQLISQY- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A4Y3PTD6_BREPA ---ELEKRLSKIVQESAGTWGVVVKELAQGICF-EHQPDELFIAESVIKVPIMAAVYAACE -QGKARIEDQLPLRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDFV-GK -ELIDQTMRELGMERSYYSRKVMIYPQD--VTANNMITAGDVARMLEHIVSGSGFSRAART -EMIAIMNKQQV-LNGLPSQLPPGWELACKSGWDT-GRQHDVGILFVEGR-QFAIAALSQD -VTPE--AALHTLGLLGRAVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus rhodochrous J45 TaxID=935266 RepID=A0A562D6X8_RHORH ------------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVAMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPQEMTRLLEAVWSGSVLSPESTD -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Chitinophaga cymbidii TaxID=1096750 RepID=A0A512RGY9_9BACT --rKLQKALQEIVDGFHGTAGVYVQNLKTGRYA-AVNADTIFPTASIVKVPILVGVFDKIE -KGELKYHQPLVYRDSAKYGGSGLMQFFKDSATELSVLLHLMMSYSDNTTSLWNQALAGGG -EQINRLMEQYGLQHTRVNSRTPGREEIWKIYGWGMTTPREMSSLVVKIFRGEVISPGASE -RMYRLMTKGYY-DETGISQLPPDVQVAAKSGSVNE-SRSEVLLVNAPHGD-YVFYVGTKN -IKEEDNEAVVMIRKISALLWRHf ->[subseq from] serine hydrolase n=1 Tax=Steroidobacter sp. YU21-B TaxID=2695855 RepID=UPI001325618F ----LNHLLEAELSRWPAHTGLYVKHLGTGEQA-RIRAQERFESASTIKVAIMVRAFQLAD -ENKLDLTSRHELTAGDYRGGSGILKYDLGLKLTLHDMITQMIITSDNTATDIMVAKVGGR -EKLNEFLREAGYKALKLNRTTHEFFRD---DETGVATPAEMGALLEGIERCTLATRQSCE -DMKRILRAQQV-THKIPHYLS--VPAGNKTGDTGS-VTNDVGIIYSLSG-PIVMASYNMD -IKGQRTELDDCIGALARRVVDYf ->[subseq from] Serine hydrolase n=1 Tax=Halomonas endophytica TaxID=2033802 RepID=A0A2N7U421_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- -ERLDWFIRRLGLEALRLPTLEAAFD-AYYASDLNSGRLDSFGDLLAELGEGRALGAAASA -ELLSIMTRTTSGDRRLKSGFGSDVRFAHKTGTQHR-RTCDAGIASHGQGRKVVVVACVR- -GESNVVRSESVMAGIGRAM---- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Saccharomonospora sp. 31sw TaxID=2528243 RepID=A0A4P7C9S8_9PSEU -------------ETTGVRAWVHARCLATGRQA-GHGAGERVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRVTAGDRLGGTGTAGCSDDVELSLRDAAFFAMSVSDNSAADLLFDRV-GV -ENVQALMTELGLTSTRVVCQPRDVVRALDPARTNASTPEDMTRLLELVWTDKAGRPESCA -AVRAWMGQQVN-WLRLGAAFPPEVSVAGKTGTLPC-VRNEIGVVTYPDGGRYAVAVFTRV -ASGRRPDIERAIGLTARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI0009C2AFB5 ------------------------------ERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLSVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGQIIS--- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Chloroflexi TaxID=167963 RepID=A0A5N9EQU3_9CHLR ---NLESTLDNIINQFEGVAGLSIRCLNNNKTI-SINGDDVFPTASSIKIHILTQLFTLED -KGTIDLAKRVRFTQDMYGAGSGVIHFLENEPFTILDIAILMMLVSDNTATNMCIDLA-GM -QETNNLIKDLGLSKTKLGRKMMDPD-AINRGEENISTPNELTKMMELLYQKKP-SPKVAN -NVLNIMSKPKS--AYLNKAIGPNTKIANKPGGMDK-VRCDVGIVYLPNN-PYAISIMSNY -GITDSLSQESFVIELAKTA---- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 112-3 TaxID=2486025 RepID=UPI000F78503B ----------------KGQNAV-FIQTTTGQTL-SWHNR-SQKAASDIKLFILATVYRQVA -AGKFDLAATYTLREADKVGGTGNLQAQAAGTVTNRDLLKDMMTVSDNTATNIIIREVGGL -AAVNQEIKRLGATQTVLRRKMMDQK-ALAAGRDNETSARDLGNLLMKIWRHQLISRAADT -AILKLMAANTN-HAKLPKLVPASRQIYNKTGEFDYGVENDAAIFAQGKQ-AVVVVALSQN -GEQQVPAMNQLGKQI-------- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sp. YIM 98839 TaxID=2663380 RepID=UPI0013DA98C9 ---ELEKSIENCFEDIQGEYSIVIEI--GNNQI-SLNGNKKMPAASIIKIPILMEGYRVIE -NKKFSEMTKIRYLEEDKVGGMGVLNSLASANLAWIDILTLMIIVSDNTAANLAIKNL-GF -SEVNRLCEEAGCKNTDLGRYFMDME-AIKKGSNNYTSANDMVFLLKEIVHGNLLSDDSKA -SILRILKHQQF-NTKLPGLLPGSLVMAHKTGELP-GVEHDVGILEYKEEK-VYIAVLLSD -LS-SNCDGQKAIAQIGELVYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. SGD-V-76 TaxID=1414648 RepID=A0A0V8JI71_9BACI ------------------------------ERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDIQAS-AEGRDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLFTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGRIIS--- ->[subseq from] Uncharacterized protein n=1 Tax=Luteimonas sp. FCS-9 TaxID=1547516 RepID=A0A0H1AUM9_9GAMM ------------------------------------------------------------- ----------------------------------------------DNVAIVRLRNAEAGE -PRLQALARELGVPRSALKADTDAVFADYYRGERNQATLPAFATLLERLIAGELLSPESTA -LMLGHMRAIGTGDRRLSAGLPPGTDFAQKTGTQVR-RACNVGVIDPEARDGATIVLACAE -DFDALTQAEQAFQTLGRAL---- ->[subseq from] Abhydrolase_3 domain-containing protein n=2 Tax=Bacteroidales TaxID=171549 RepID=A0A255TFK0_9BACT -------------------------SIMNGELYcGHQEDSAFAMHSVMKFPQALYVADYLH -KKGLTLSDSVLVHKDSLDAWSPMLSIFEGMRFTFAELIEWSLKQSDNNACDLLFASCGQP -DAVEKYIHTLGFKDIHVQLTEKEMKKIPHRAIENSATPKEMARLLEWFYLHRD-DNKNLS -FIWDTMADCNTGQQRIAAVLPKDGKLIHKTGSGFRQDRNDVGIVLLPDGSHLSIAIFFPK -SKEEKEVAEV------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea jiangxiensis TaxID=633440 RepID=A0A1G8F0J3_9ACTN --------------RAGVTGWLYAADIESGREI-GHGADEPLPTASMFKVALLVEFCRQAD -AGLLDPACRVTVPGGAREAPTGIAVMLDDVTISLRDLAYLMIAVSDNSSADALLGRI-GF -DAVNAMLDALGLEVTRVTQSCETMNRALDPARTNRSTPREMARLFRLIWRDEAASPAMCA -WMRSVFKLQVW-PHRLASGFPDDVAVGGKTGTMPT-LRCESGVVEYPDGRSYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. BL8 TaxID=1354301 RepID=T0PHS3_9CLOT ------DVISNCIKDFNINCAIVVKNLNTGEEV-KVNEQMAMPAASIIKLFVMGEVFNNIN -KGKIFLEDKITVKEEQKISYQLLTLFDEDREFTIRELLKLMICQSENTATNILIDMV-DI -DNINSFIKSLGFKNCEIQRKMLDMEAR-MQGKENYISAIEVSKFLELLYNGKIINEKCSK -QMIDIMKSQLL-VAEVHRYIPDNIGLALKTGDVW-GYKHAAGIFYIDNCD-YIFTMLINY -KDDEIKLMDEFMGKMSAAVYNYf ->[subseq from] Beta-lactamase class A n=2 Tax=Hydrobacter penzbergensis TaxID=1235997 RepID=A0A1H2VQJ5_9BACT --qRLQQQVTQLLKGFNGDIGIYVHDLKRNRIV-SINADTVFPTASMVKVPILTGIMDKIH -RKELDYHQVLTYKDSLLYEGVDILGSFKNDEIELSKVMMLMLTMSDNTASLWLQTLAGKG -TRINELMDSLGLKVTRVNSRTPGREANRNMYGWGQSSPREMASLMEMIVKKQVISDSTSQ -MMLRLLGRNYW-DENAISQIPSDVFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN -NKESTNEAWVLTRKLSKLLWEYy ->[subseq from] Beta-lactamase n=1 Tax=uncultured Clostridium sp. TaxID=59620 RepID=A0A1C6LDE1_9CLOT --------------------------------------KVSFPSASTIKIFIAIEAFNQIN -KGVIFEDDIILLDGTMKVGGSGILSNYPNNSISIKKLIYLMMTQSDNTATNILIDIL-GM -NNINITINKILCKNSALNRKMMDFDS-IKRGIDNYTSASDLTIVLEKLYTNTCINKKYDT -LILNIMKDCAN-TSKIPKKLPSNITVSHKTGELDY-IENDVGIIFTPYGD-YILTILTQG -CNN--LDEIEAISELSKIIYDSy ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9T3Z7_9BACT ---SLRRELEQIRNHFPGDMSIYMKNLSTAEEI-ALDSDKVYETFSVIKLAIAAELMHQVE -SGKLSLSDRIITRAADERLPSGVLYALEPGLPTIKDLLTLMIITSDNEATDLLADKL-GR -AQVTAYMHALGLANTSIQFSDLDWDRYDAGIFFGHSTTKEIGRLLEMMASGKLVSKDASE -LILNIMEKQQV-NDRFPRYLK-DVRIAHKTGDGQPFIANDVGIIWVKDQ-PIVLVVFTGH -HRGG------------------- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2ECT0_9ACTN -----RPDFESLFRRAGVTGWLYAADIDTGREV-GLGPDEPLPTASMYKVPLLVAFRRQVD -AGLLDPAHRVTVPASDRLAGTGIAAMQDDVTISLRDLAYLMISVSDNTSADTLLELV-GC -DTINAMLDEFGLTGTRVVQSWREGSAVLDPARSNCATPRELATLFAMIWRDEVASAESCA -WMRGMLNLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRAESGVVEYPDGGRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium haloxyli TaxID=2100533 RepID=A0A2S9IUD8_9SPHI --tKLERMLQDEIKDFRGDVGVFVQHFKNNKTV-AIHADTLFPTASVVKVPILIGVFDKIG -RGQLKLSDTYIYDANRIYGGSGLMQFYKDSSTNLSTMVSLMLTYSDNVASIWCQELAGGG -TTINQLMDELGLPNTKVNSRTAGRQEIWEKYGWGQTTPREIVQLMTMIRESRAITPRLSD -KMYRYLKNQYYNG-EALSQLPPHIATISKTGALNQ-TRNEVVFVHAPSGD-YAFAVLTKN -NDSPDNEAEVLIRKISYILWNYf ->[subseq from] Beta-lactamase class A n=2 Tax=Paenibacillus sp. 453mf TaxID=1761874 RepID=A0A1I6PNW9_9BACL -------------HQGGIRVTVSVVDLSGNVGF-LIGSEEQYKSASTIKLAIACALLQMVD -RGEICLEDQTVVRNEDVVGGSGSLQQEVMPLATIGRLARLMIAQSDNTATNVLIDVV-GF -ERVRALLEGLGIHRTQLGRKMFAPVHS--PELDNYADAQELTRLLKLVYQGELLSEYSRR -LLLIWMSKQEV-NTKFGAVLG-DMLIAHKTGEAGN-VTHDTGYFLIPGRE-LAVAVMTEV -MTEAQRIGNPVVQRIGKVIYDQ- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sulphureus TaxID=47758 RepID=UPI00037666F3 -----RTRIEAAFAEAGVTGWLHARDIDSGAQV-DAGADHSVVTASVHKLPLLVALHREAE -AGRLDLTERTHCPPTGRTPGPTGLAAMLDEALSLRDAAYLMVSVSDNTAADLLLERV-GL -DSVNAATRELGLTRTRALHTFAEFLAALDPRRSNHSTPRDMTRLLASVWRDEAANPAHCA -AMRRLLGLQVW-PHRMASGFPDDVHVAGKTGSAPT-LRNEVGVVEYPDGGRYAVAVFTRA -GSAALPAADAVIGTAARLAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Balneola sp. EhC07 TaxID=1849360 RepID=A0A1B6YAL1_9BACT ---ELKEKIDLELSTLEGDFAIAYRDINHPEQQiLINVDERFHAASTMKTPVLIELYKRAE -NTDLDLQDSILIKTESIVDGSPFSYRNLNKNTTFYKLAYEMITRSSNLATNILIDYL-DA -EKVTSTMRDLGADSINVLRGVEDLKA-YRQGLSNTTTARDLLVIFEHLSSDTLISEEANK -EMLGILKDQVY-NDMISAKLPEGTEVAHKTGWITN-VHHDSGIVFTGKDEGYILIFLSKN -AP-DRAAVLEAAANISSMIYNY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=UPI0009EE9918 --qELRERVRTVVNSTAGHVSFMMED-EGGNQY-QIEADTHKKAASLIKIPILMAAFKQVE -AGRLKLTDRHLVEAESRVGGAGVISQLDAETFTLLDLLTLMIIVSDNAATNKVIDML-GM -DDVNEFCTKHGLSKTKLERKMMDFKAA-GQGLENRTCARDIVKCLKLLLENGVFTEENRL -QMLKILDGQQL-LDKLPFLMDDSVTIANKTGELP-GVEHDCGIVALGEK-KVLVAVLIDD -LT-DNAVGKKAIQEIGKIVEK-- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000E24816B ------------------------------------------------------------- -------------------------------------------TYSDNTANNKIIKEIGGI -KKGKQRLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus rhodochrous TaxID=1829 RepID=UPI00132EC872 ------------------------------AML-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAIAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0N0HLN7_9ACTN ---------------------VAELH-RPSARV-TIDPDERLPMGSVYKVPLMVAFCRLVD -AGLIDPGRRLTLAPDDRVPPTGISILHDPVTMSLRDLVVLMMTISDNTAADAVLRVV-GP -DVVDAMCGDLGMPDTHIHGGVVTTFSVYDPAFKASTTPADMARLLRAIWTGQAASDERCA -FMRDVMRRQPW-THRLASGFPDDVTVYGKTGSFGS-MRHEAGVVELADGSTYTAAVFTQA -ARAKLPRADAVIGAAARTAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Marinimicrobia bacterium CG1_02_48_14 TaxID=1805240 RepID=A0A1J4XK69_9BACT -----------------KRIAVAYRNLGTDEVK-AFMPLEDFHAASTMKTPVMFQLFKMRD -EGKLNLSDSVTVTNESILDGSGYTYLKLGRNVAIRDLIEKMITRSSNLATNILIEIA-DP -VKIAETMKQIDAFGVFVLRGVEDIK-AYEAGLSNRTTAGGMMNMMTAVYRSNRVADTSRQ -EMIDILAAQHF-NDMIPKGLPDGIKVAHKTGSITR-IAHDAAIVFPPNADPYVLVILTSG -YD-DNTEAQALGARISERIYAY- ->[subseq from] zinc_ribbon_2 domain-containing protein n=1 Tax=Enterococcus sp. 3H8_DIV0648 TaxID=1834178 RepID=A0A242DGR5_9ENTE --------------KLQNKTGVFVSMIDEKNIDyEKSGTAPIRAASIIKLFLMEAFYREVN -EGTIRLDEPYVLKDTDKVSGTGVLQNYAEGTLTYEDLIRHMIVDSDNTAGNIVMNILGGP -ENITKFIYTQGFNDTRIERKFVDST-ALAAGKDNYTSAVDVGNLLKKIYQRKAVSPRYDQ -QMLEILKYNKN-HSKLPKEIDSEVNVYNKTGEYDYGVQNDACIFETNRN-AYVVVVLSED -GDESQ--QVSAMN---------- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. CF418 TaxID=1855287 RepID=A0A1M7QYK3_9BACT --rKLEKGLRELIKDFNGDIGIYVRNLKTGRYM-GINEDTIFPTASIVKIPILVGVFDKIE -KGELKYHQPFIYRDSIKYGGSGLMQFFKDSTTDLSVLLALMMSYSDNTTSLWNQALAGGG -QRINELMEQYGFSVTRVNSRTPGREGIRNIYGWGMTTPHEMAELVVKIRQGEIISKAASE -RMYRLMTHGYY-DETGLSQIPPYVQAAHKTGSVD-ASRSEVILVNAPHGD-YVFYAGTKN -NKTDENEAENLIRKISKYLWEYf ->[subseq from] serine hydrolase n=1 Tax=Sediminibacterium sp. WSJ-3 TaxID=2698829 RepID=UPI00137970AA --kRLQRRLSEMFRDYPGSIGIYVHDLKKNKIV-AINADTVFPTASMVKIPILTGIMHKLE -SGELNYHQTLTYRDSLLYEGVDILGSFKNNEIELSKLMMLMLTMSDNTASLWLQSLAGTG -TRINELMDSLGMRYTRVNSRTPGRENNRAEYGWGQTTPLEMATLMEKIVRKEVINAAASE -KMLRLLGRNYW-DEVAVSAIPADAFVASKNGAVN-ATRNEVVFVNAKKS-RYLFCICTKN -NKEPGNAAWVLTRAVSALLWKYy ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E3DWL4_9CHLR ---NLESTLDNIINQFEGVAGLSIRCLNNNKTI-SINGDNIFPTASSIKIHILTQLFTLED -KGTIDLAKRVRFTQDMYGAGSGVIHFLENEPFTILDIAILMMLVSDNTATNMCIDLA-GM -QETNNLIKDLGLSKTKLGRKMMDPD-AINRGEENISTPNELTKMMELLYQKKP-SPKVAE -NVLNIMSKPKS--AYLNKAIGPHTKVANKPGGMDK-VRCDVGIVYLPNN-PYAISIMSNY -GITDSLSQESFVIELAKTA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Allokutzneria albata TaxID=211114 RepID=A0A1G9T7F0_9PSEU ----VAAEVAERFADAGVTGWLHAREIDGTREV-SVGADTPVVLASVFKLPLLVAVFRAAE -TGEVDLAGRVTLDPGARSSPTGIGAMFDQVSMSVRDLALLAMSVSDNAAGDALVDLV-GF -EAINRVTESLGLTTTCVVQRSRELTEALRPESTNRSTPREMTALLAALWRDEAASPESCA -AMRRLLGLQVW-PHRLASGFPDDVRVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTAS -VRLTLPAADAVIGTAARVAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34) TaxID=709986 RepID=E8U6Q1_DEIML -------------RGFPGVAALVVEDLHRGERLvELQGARAFPAASTIKVPLLVHALQRVQ -AGALNLGARVPVPADARVPGAGVLHELDGGLPTVRDLLTLMIVVSDNTATNLVIDLL-GE -AAFNAWLQAEGLRGTHLVRPPHLQNPAQRRGERNRTCADDQVTLLSRLARGELLNPELTA -LALDVLSRQQV-RPILARHLPLSVRVASKSGELR-GVRHDVGVVWLP--RPLVVAVLSEG -GADAR------------------ ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7U5E7_9BACT -----------------ERLGIAFYDAETTLQW-SYNADAVFHAASTMKLAVLLAVFRQYT -RGELALDEPVHVRNKSIHDRRPYMYERLGRTMSVGRLAYHMITSSSNFAANLLVDVV-GV -PVIRTALAEMKIDGIKVLRGVEDQ-AAFDAGLNNEVTANGLLKLLRLVAEGMAYGEEASA -RMREILLDQRF-KSGIPAGLPPAARVAHKSGNIST-VHHDAGIVYLEGRRPYVLVVLTQF -PS--EAGLTTAVADVSRDIYE-- ->[subseq from] Beta-lactamase n=1 Tax=Leadbetterella byssophila (strain DSM 17132 / JCM 16389 / KACC 11308 / NBRC 106382 / 4M15) TaxID=649349 RepID=E4RZ75_LEAB4 --qKLQRQIEQEIKGFRGEIGVYVKHLKSGKEV-RIQADTVFPTASLVKVPLLVGIFHQIH -DGKYNLDQEFIYDAKRVYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSLWIQELAGGG -IQVNQLMDHYGLKDTKVNSRTEGRAKIWEKYGWGQTTPKEMATLFTLIREGKIINKEQSV -KMYRYLKNQYY-NERSLSSLPPTVNTISKTGSVNQ-ARGEVVLVNAPHGD-IVFCILTKN -NETPLNEAEELTRRIAKLIWNFy ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E0D41EF ----------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQVD -EGLLTLTSVIQRTEKNTVGGAGVLGALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECARNIGLKKTVLNRYMMD-ETAVKQGVDNYTCASDVVECLREIYEGNFLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter radicis TaxID=2172650 RepID=A0A2T9JJ87_9CAUL -----------AERARPGDLGVAVQDLTTAQRA-AVAGEHLFPLAGIWTAALGAAVLAEVD -AKALSLRETITIEDVDLSPPSGVADAWPSRRWTVEDLLKHAVADGDNTAADVLMKRIGGP -GAVTAWLDLKKVENLRVDRYARQLLSDYLADPHDSVTPLAAVRFLEALNQGELTSQENRR -RLLRMMEAAA--GERLRPALPAGARLAAITAATPTAADNVLAMVRLKDGRRFALAIFLKA -SPLEEADRDALMLEVMRTVMQ-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A2W4NYY7_9BACT --rDLNRSLQQLVSEFPGRVGIYVRHLKTGEEV-AINADTVFSTASMIKIPITIGIFDKIE -KGELKYDTVLTYRDSLASKGEDVLGSFKDGQISLAKVLMLMITVSDNTASIWSQEMAGGG -VTINAWLENNGFTHTRVNSRTPGREDAWKRYGWGQTTPREMANLVSMIRNNKVVSPRASE -RIYRNLVRIFW-DGSSLSQLPPYVQAASKTGSLDH-YRSEVVLVNAPHGD-YVFCVIADR -FETPDNAGNVLLRDVSRLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4NGV3_9ACTN --------FDTLFSTAGVRGWLHAADIDSGREV-GHGADVPLPTASMFKVPLLVEFCRQAD -AGLLDPSDRVTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR -EAVNTMLAALGLHGTRVLQSCQEFNDALDPERTNRSTPREMSALFGMIWRDEAASAESCA -WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus reticulitermitis TaxID=856736 RepID=A0A1H6U1V3_9DEIO ------------ARGYAGTAGLVVLDLQTGETLyEEHADRPFPAASTIKVPLLVLALQAAE -RGELVLTGRVTLQAEDRVPGAGVLHELEPGLLSWRDVLTLMIVVSDNTATNLLIEQL-GL -EACNAGFRALGLRATRLVGPLERRNAAQRRGERNRTSAREQAGLLRQLGRGDLLGPEHTG -WAQDVLFRQQV-RPLIGRGVPADYRLASKSGELR-GVQHDVALLHTP--RPLAVALLSEG -GTDPREHP--------------- ->[subseq from] serine hydrolase n=1 Tax=Actinospica acidiphila TaxID=304899 RepID=UPI0013D40E95 -----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA -RGALDLAEQVESVPEGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GM -EAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEAGAPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D4YK31_9BACT ---ALRRKLDSIADAHHGVVGYSVIDLETGARI-NRRGDETFPTASLIKVAILVTVYDLVA -KGQLSLDDPLTVLKIDQVPGSGVVQFHNGTVLTVHDAAWLMSTISDNTATNLLLDRI-II -RRVWAKMDSLGLQHTRVHSKSFLRNSSVAMDSSGVTTPNEMAHLFELMALGKAVNPAADS -AMLDILEHNTT-DFMLQRYLE-GARAAHKDGETD-AVRTECTLWYLRNR--VVACVMTKE -NKDQ------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces xiaopingdaonensis TaxID=1565415 RepID=UPI0002DE5CFD -----RTRIEAAFAEAGVTGWLHARDIDSGAQV-DAGADQSVVTASVHKLCLLVALHREAE -AGRLDLTERTRCPPTGRTPGPTGLAAMLDEALSLRDAAYLMVSVSDNTAADLLLARV-GL -DAVNATTRELGLTRTRALHTFAEFLAALDPRRSNHSTPREMTRLLASVWRDEAVDPAHCA -AMRRLLGLQVW-PHRMASGFPDDVHVAGKTGSAPT-LRNEVGVVEYPDGGRYAVAVFTRA -GSAALPAADAVIGTAARLAVE-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A3D5NZZ2_9BACT -----------------KRIAVAYRNLGTDEVK-AFMPLEDFHAASTMKTPVMFQLFKMRD -EGKLNLSDSVTVTNESILDGSGYTYLKLGRNVAIRDLIEKMITRSSNLATNILIEIA-DP -VKIAETMKQIDAFGVFVLRGVEDIK-AYEAGLSNRTTAGGMMNMMTAVYRSNRVADTSRQ -EMIDILAAQHF-NDMIPKGLPDGIKVAHKTGSITR-IAHDAAIVFPPNADPYVLVILTSG -YD-DNTEAQALGARISERIYAY- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium indicum TaxID=759821 RepID=A0A3E2NA19_9CLOT -------------EKLPGKISFLYENLETGERV-GYREDQPLMAASVIKLFVMASVFDQFE -KRKLKQDFSLPIYKKDCVPCGALTYLHEGICVTALDLVTLMIIFSDNTATNVLIDLL-GM -EEINRYIESLGFKNTRLNRKMYDVEKS-AQGIQNYITASETGRLLTMMHRGELVSEAASS -QMISILKNQQL-CSKIPFYLQEEPEIAHKTGEDR-GITHDVGIVYGK--VPFLV-CFCGN -ET-DTPAFERIMGELSLELY--- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 116-2 TaxID=2486004 RepID=UPI000F7A8037 --------LSNNLAGIKGDTSAFYYNLNDNDSA-SYGDDEDQRAASDIKVYIMAAAYQKVD -DGEISLNDRYELTSEDKVGGTGVVQSQVGDSLTYRDLIDYMITKSDNTAANIITKEIGGL -DAVNDEIDELDLSNTKMERMLMDQD-ALSEGKDNMTTAHDLAMFMRKLYQHDVVSDKYDK -QMLSILSNTSN-HSKLPANINTNVDVYNKTGEYQYGVENDAAIFKRGNKA-FVLVVMSQN -GDSD--EQKDAMGSLGKEVTQ-- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. R-22-1c-1 TaxID=2487040 RepID=A0A3M9MTQ2_9BACT ---KLTQKLQALTKDFQGEVGIYVKNLKTGRIV-AINADTLFPTASMIKVPIMVAMFDKIE -KGEIDPKTILRYRDSLYYAGEDIVGNFKDSSVALGKIQMLSITTSDNTGSLWLQQLAGGG -TAINVWLEKNGFTHTRMNSRTPGRRPNWEKYGWGQTTPREMASLVTMIRDGKAVSPAASE -RMYRNMGRIYF-DNEALSQIPPYVHTASKSGAVNQ-SRSEVVLVNAPHGD-YVFCIITKN -QKDENNAGYALIRAVSKTLWQHf ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5F255_9ACTN --------FDTLFRTAGVSGWLHAADIDSGREI-GHGADAPLPTASMFKVPLLVEFCRQAD -AGLLDPSDRVTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR -EAVNTMLAALGLHGTRVLHSCQQFNDALDPERTNRSTPREMAALFGLIWRDEAASAESCA -WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga arvensicola TaxID=29529 RepID=A0A1I0S964_9BACT --hKLEKGLKELIAGFNGDIGIYVRNLKTGRYA-AIHADSIFPTASIVKIPILVGIFDKME -RNELTYHQPLLYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTASIWNQSLAGGG -QRINELMAQYGLNVTRVNSRTPGRADIWKIYGWGMTTPREMAELVVKIRNGEVISKAASE -RMYRLMTHGYY-DEGALSRIPPYVQAAHKTGSVDE-SRSEVVLVNAPHGD-YVFYAGTKN -NKTDDNEAQVLIRNISAWLWNYf ->[subseq from] Beta-lactamase class A n=2 Tax=Lactobacillus silagincola TaxID=1714681 RepID=A0A1Z5J503_9LACO ----------RCIASASGQTSVYAVDLRNKQPVmVHNRSQ--RSASVIKLFIMVEAFRQIK -SGRLTLNQEVSIPKTDQVGGTGELAHQNVNQLSLIRLLTLMIRNSDNTATNVLIDRLGGL -NVINNEIKRLGCSDTQLQRKMLDYQS-LKNGKDNMTSVKDVGNLLVKLEQHSVLGDPYDA -EMLQLLRYNAN-QSKLPALINQKATVFNKTGEFDYGVQNDAAIVKKGNQ-VFVVVVLSQH -GNES--KQVGAMQQLGKQLYTI- ->[subseq from] serine hydrolase n=1 Tax=Chitinophagaceae bacterium YG09 TaxID=2608880 RepID=UPI00129BB497 --kKLEHQLKQLVAGFRGDVGIYVLDAKKNKVA-AINADSVFPTASIVKIPIMIAVMDKIE -KGQLSYHQRLTYTDSLYYNGDDILASFKDSSIELSKVMMLMLTTSDNCASLWLQGLAGTG -SRINEILDSTGYTQTRVNSRTPGRQGNRAQYGWGQTSPREMVTIMSRIVNGSMLSPQASE -KMLRLLGRQYW-DEEAISQIPPGVFVADKNGAVD-ASRSEVMFVNGP--HPYTWAIFTKN -NQDTNNEAWVLTRKVSALLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ZS0098 TaxID=1904044 RepID=A0A421P563_9ACTN -----VARIHAALTDAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHEQAA -RGALDLAEQVESVPQGRTAPTGVAAMLDTARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTDRLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACAPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Sphingobacterium TaxID=2609468 RepID=A0A077XRC7_SPHSM ---KLERKLRVLTQNFQGDIGIYVKNLKTQKSV-LIQADSIFPTASIVKVPILVGVFDKIE -KGELNLDQKFTYRSSQQYGGSGLMQFFKDSTTDLSTLVGLMISYSDNVTSIWNQQLAGGG -LVINELMDKLGLVNTKVNSRTVGRDDIWKKYGWGQTTPREMATLVEMIYQGKVISSKSSD -QMYRYLGNIFY-NERSLSQIPPYVKTASKTGSVDE-ARGEVVLVNAPSGD-YVFCVLTNN -IKTKHNEAEELTRKISHLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536A0M4_9CHLR -----------ALASLPGEAAAFASDTYGHALF-CEREDELFPSASVIKLPLVMTLYADAA -RGRLDLDERVAVG--DRVDGSGVLRHMRDVELSLRDLAMLAVIVSDNTATNRLIERI-GV -DRVGERLREWGCPTSRLSRKMYDFEAA-KRGNENVMTARETVSLLVRLERGECEDRTTSD -AVLGILEQCQD-RTMLLRYLPYGTKVPHKTGTLDE-SRNDAAIV--PGERPVIVAAFTRK -LRD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Lysobacter alkalisoli TaxID=2591633 RepID=A0A514BWP8_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GE -ARLVALAKALGVPRDELDRDLDDVFGRYYETGRNSATLEAYALMLEKLVTGELLSEASTR -RILDHMRAITTGDRRIQAGLPSGTDFAQKTGTQV-ARACNVGVLDPDKGGGATVVVACAE -DFEDLAQAERAFREFGQAL---- ->[subseq from] serine hydrolase n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=UPI000BE39D1C --------------KDGAEISILVKDFKTQDILySHEDTKEVVSASIIKVPIMLTALEQVE -KGKLELDSFIELKDAGILEDTEVFE-YGGGKYTLEELLVWMIIESDNTATNCLIDLL-SM -ETINTFCKKHSLKSTKLERRMLDFQAV-QEGRNNYTSAGDMAILYEELYNRTILTPDLCN -TALGILKRQRH-KQLSLRYIYDDITVAHKTGSLDN-LDHDAGIFYLPNIQ-YYFGAFVWN -AP-SNEYASKWIGRISKGIYEYy ->[subseq from] Serine hydrolase n=1 Tax=bacterium BCRC 81129 TaxID=2487722 RepID=A0A4Z0J8L0_9BACT --------------RLAGQNAVYIQ-TTAGQTL-SWH-DRSQKAASDIKLFILATVYRQVV -AGTFQLATPYTLREADKVGGTGNLQAQPAGTVTNQALLKAMMTVSDNTATNIIIREVGGR -AVVNREIQRLGATQTRLRRLMMDQK-ALAAGRDNVTSARDLGQLLMKLWHHQLISPTADT -AMLKLLAANTN-HTKLPANVPASRQVYNKTGEFDYGVENDAAIFAHGQRA-VVVVALSQH -GQEQIPAMNRLGQQV-------- ->[subseq from] Beta-lactamase n=61 Tax=root TaxID=1 RepID=A0A1U9XDT1_ECOLX ------------------------------------------------------------- ------------------------------------------------------------- ----------MGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. FJAT-25496 TaxID=1742359 RepID=A0A5B8Z0B3_9BACI ----LEKAMEKVAACCEGRIGFVLET--GNSRI-ERNSEVKFSSASLIKIPILIEGFRQND -RGLLDLQEEITVLPKDQVGGAGVLQALSADLIKIIDLMALMMVVSDNTATNLLIDRV-GK -NEINKCMKEIKLKWTELNRKMMDFE-AIKSGMDNWTTAHDMVTCLKIIDQQFFLSKESSQ -KAFSIMEKQQF-KKLFNTIDLEDLQVASKSGELP-GVEHDCAIIRYGDKT-IYSAVLIDQ -LK-DPYEGKQILSQIGKLILRH- ->[subseq from] serine hydrolase n=1 Tax=Bacillus flexus TaxID=86664 RepID=UPI0013CF7991 ------------------------------ERI-EQGATNVYPSASTIKLLIAVEACRQID -SGVILVQQTIAVKQSDLVGGDGILHVYPYLPVTVKELVLLMLILSDNTATNMLIDLL-GQ -DRIQACINDLGLENTQLNRQMMDAQAAVEG-RDNVITAADLLTCLKVLYREDVLSKDSRD -FLKGSLLNQRM-RDKLPSMLNEECFILNKPGHLR-GITHDCGVLVTHHKR-CYAVVLIDG -LE-HNEYGRRLIADLGRIIS--- ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter luteus TaxID=572036 RepID=A0A1T5C2L7_9SPHI --rKLKVKLEELVKGFQGDVGIYVQNLKTGRIA-EINADTIFPTASMIKVPIMCGVFDKIE -KGKLKYDENLIYKDSLLYAGEDILGSFKDGEIKLGKVQMLSITTSDNTASLWLQKFV-GG -ENINKWLDANGFKSTRMNSRTAGRQGDWRKYGWGQTTPREMATLVKMIHEGKAVSPAASE -RMYRNMIRIYW-DAEALSQIPPYVQAASKQGAVDR-SRSEVVLVNAPHGD-YVFCITTKN -QKTPDNEGYRLIRGLSRLLWNYy ->[subseq from] serine hydrolase n=1 Tax=Salinicola halophilus TaxID=184065 RepID=UPI000DA11552 ------------------------------------------------------------- --------------------------------------------------------NI-GP -ERVEALRRVLDVEADALEEDMTEAYSRYYDREVNSATLESYAGLLTALVRGELLDDAHRQ -LLYENLKLDTYDAYRLEGGLPREAAFIQKTGTQHR-RACHMGVVEPTDPDRAIVITACTE -AMDEAAPSEALLKRVGEAIAE-- ->[subseq from] serine hydrolase n=1 Tax=Chloracidobacterium thermophilum TaxID=458033 RepID=UPI000738A51C ---AMTRRLQRRLAAFKGKVFCFAKNLDTGETF-GYNPDARVRTASTIKVPIMVEVFAQVA -EGRLRWDDKLTVVRRHEYEGGVLFELTPGTQITVRDAVRLMIVVSDNIATNILLDRI-TT -DAVNDRLAQMGFEHIRSLRKIAGGGEENKKYGIGVATSREMVRLLEGLERGTVVSPEASR -EMLAIMKRQQY-RDGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKHG-RIAMAITVED -IPCSEAEGHLLIADI-------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 44-15 TaxID=1895837 RepID=A0A1Q4EZT7_9SPHI --kKLEREIQNLVSGFHGSVGIYVHDLKRDRIV-AINADTVFPTASIVKIPILLGIMQKIS -TGELDYHQRLTYTNDLFYDGDDILSRFKDSAIELSKVIMLMLTISDNCASLWLQQLAGGG -TRINQVLDSLGYSTTRVNSRTAGREAGRAQYGWGQSSPAEIAALMEKIVKGEIFNREASA -KMLRLLGRQYW-DEQALSAIPAGIFAADKNGAVD-GSRNEVVYVNGPKR-PYIFSIFTKN -NQEKNNEAWVMTRKLSALLWEYf ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Rubrivivax sp. TaxID=50259 RepID=A0A519HPY5_9BURK -------AFAALERRVQGRLGFFAIDTGSGRTL-AHRADERFAIASTLKVLLGARVAHGVE -AGRWGWNDAVPLRESERVPHSPAFDRLLPRGATLAELVQGIVVESDNPCANVLLRHCGSP -SGLTDWLREQGDQVTRLDRWETELNENAPGDERDTSTPRAFART---------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 48-107 TaxID=1895840 RepID=A0A1M3GHI9_9SPHI --kKLETRLREAVSGFNGDIGIYVKNLKTGKIA-VFNADTIFPTASIVKVPILLGIMQKLE -RGELVYDSTIIYRDSLLYAGEDILGSFKDGEIRLKKVMMLMMTTSDNTASLWLQGLAGGG -TSINQILDSLGFKDTRVNSRTPGREDIRKLYGWGQTTPREMGEIFERIYRNEIFSPAACD -RMMRCMGRNFWDQEEAISVIPPYIEVFSKNGCVDQ-SRNEALLVNAPNN-PYIFCIFTKN -NKRKSNEAWTLTRKISTMLWEYf ->[subseq from] Serine hydrolase n=1 Tax=[Flexibacter] sp. ATCC 35208 TaxID=1936242 RepID=A0A1V2B2P7_9BACT ---KLEKGLRDVISGFHGDVGIYVRNLKTGHYA-EINADSIFPTASIVKVPILVGVFDKIE -KGELQYHQPLIYRDSAKYGGSGIMQYFKDSSTELSVLLALMMSYSDNTASLWNQALAGGG -ERINQLMEQYGLHVTKVNSRTAGRQEIWKIYGWGMTTPREMTTLMIKIRNGEIISKSASE -RMYRLMTHPYY-DEGAISAIPPYVQAAHKSGAVDE-SRSEVVYVNAPHGE-YAFYIGTKN -IATDDNEASILIRKVSKYLWEYf ->[subseq from] Beta-lactamase n=3 Tax=Rhodococcus TaxID=1827 RepID=A0A059MV61_9NOCA ---SAEDRIRDVFADAGCTGWVHARRCDSADEV-TVGGRERVVTASVYKLPLFVAFCRCVD -AGLVDPTAPLTVTPAECTPPTGIAVLHDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GM -GPLDGLLDHLGLTQTKIVGGTADLHRAYDPAYTSATTPEEMTRFLREVWAGRVLSAEQTE -FVRAVMRRQIW-PHRIASAFPRGVSVAGKTGTVGV-IRNEVAVVEFPHEQPVAVAVFTRA -ARVDLPVVDAAIAEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium olei TaxID=2571155 RepID=A0A4V5MN51_9SPHI --kKLEDKLKNEIQNFQGDIGIYVQHVRQNKYV-AIQADTIFPTASIVKVPILVGVFQKIA -EGQLQLNQSFRYDEKRVYGGSGLMQFYKDSATDLSTMISLMLTYSDNVSSLWLQELAGGG -TGINPLLERLGLQQTKINSRTPGRKEIWKKYGWGQTTPKEMATLFLLIRNGQLIGQKYSD -KMYRYLKNQFY-NERSLSQIPPYINTISKTGSVND-ARGEVVLVNAPSGD-YVFCILTKN -NKNDQNEAEVLTRKISNIIWNHf ->[subseq from] serine hydrolase n=1 Tax=Deinococcus maricopensis TaxID=309887 RepID=UPI0011D22E6D -------------RGFPGVAALVVEDLHRGERLvELQGARAFPAASTIKVPLLVHALQRVQ -AGALNLGARVPVPADARVPGAGVLHELDGGLPTVRDLLTLMIVVSDNTATNLVIDLL-GE -AAFNAWLQAEGLRGTHLVRPPHLQNPAQRRGERNRTCADDQVTLLSRLARGELLNPELTA -LALDVLSRQQV-RPILARHLPLSVRVASKSGELR-GVRHDVGVVWLP--RPLVVAVLSEG -GADAR------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Melainabacteria bacterium RIFCSPLOWO2_12_FULL_35_11 TaxID=1801609 RepID=A0A1F6QD93_9BACT --------IHAKIKQYGLTCGVCIKPSWFKNPI-NINSDYIFPAASLIKIPIAVILLIKID -KKEISWDRILTLKHYHYAQGAGYLRKKTGTKIKLREAFRLMLTISDNTAANMIIDLLGGV -SSINKQIAVFGLKNTKLVTLLGDFKGA------NKTSPGDLAILLEKSLEGNLLSKSSKR -ILKNTLMDVEN-KSLIKKGLGKYTRFAHKTGTIGI-CVGDAGIIYLPFGKRITISIVVKR -PFNS-LNGQKFIREISRLVYE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0005ECD334 ----------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLVIEAFRQVD -EGLLTLTSVIQRTEKNTVGGAGVLGALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECARNIGLKKTVLNRYMMD-ETAVKQGVDNYTCASDVVECLREIYEGNLLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus apodemi TaxID=307126 RepID=UPI00046B0603 ----------SKMANVSGDKTVYVSPVNEDKSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTIDLSDTYTLKDSDKVGGTGVIQNMDAGQFTYRELLTYMIDESDNTAANIMIEALGGL -DKVNSQIQKMGAKDTKLQRMLMDTAS-LKAGKDNITSAADVGELLKKIYNHKFISKSDSQ -EILAILEKNQD-HDYLVKNIPSEATIYNKTGIMQYGVLNDAAIIKNSKGA-FVAVVMTQN -GEI--SEEQAAMNSLGLALY--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces albireticuli TaxID=1940 RepID=A0A1Z2KUZ9_9ACTN -----RGRVHAAFAEAGVTGWLHAVDIDSGAQL-DAGADQPVVTASVHKLCLLVALHQQAE -AGRLDLSEQTMCPPRDRTPGPTGLAAMLDDVLSLRDAAYLMMAVSDNTAADLILERV-GL -DAVNHTTRCLGLTRTRAVHTFREFLTVLDPAATNRSTPRDMTRLLAAIWRDEACAPEHTA -AMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -SSAVLPPADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus apodemi DSM 16634 = JCM 16172 TaxID=1423724 RepID=A0A0R1UBJ8_9LACO ----------SKMANVSGDKTVYVSPVNEDKSY--LLNNQTQSAASVIKLFILAAAYAQQK -IGTIDLSDTYTLKDSDKVGGTGVIQNMDAGQFTYRELLTYMIDESDNTAANIMIEALGGL -DKVNSQIQKMGAKDTKLQRMLMDTAS-LKAGKDNITSAADVGELLKKIYNHKFISKSDSQ -EILAILEKNQD-HDYLVKNIPSEATIYNKTGIMQYGVLNDAAIIKNSKGA-FVAVVMTQN -GEI--SEEQAAMNSLGLALY--- ->[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. L294 TaxID=1643920 RepID=UPI0008376226 --qKLTSQLKSATKGFNGQVGIYVHNLKTGKTV-GINADTLFPTASMIKVSILSGLMDKIE -KGEMLYNQKLVYRDSLLYAGTDILGSFKDKDIQVSKVALLMITMSDNTASTWLQKLV-GG -DYINNWLDQNGFKVMRVNSRIPARKAIWEVYGWGVTTPREMCRLFTLIHDGKVVSPAASE -RMSRMLNRIFW-DNTALSQIPPYVQTISKQGTVD-ASRSETVLVNAPHGD-YVFSVITKN -NKAPDNEASTLIKKVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536R109_9CHLR -----------ALASLPGEAAAFASDTYGHALF-CEREDELFPSASVIKLPLVMTLYADAA -RGRLDLDERVAVG--DRVDGSGVLRHMRDVELSLRDLAMLAVVVSDNTATNRLIERI-GV -DRVGERLREWGCPTSRLSRKMYDFEAA-KRGNENVMTARETVSLLVRLERGECEDRTTSD -AVLAILEQCQD-RTMLLRYLPYGTKVPHKTGTLDE-SRNDAAIV--PGERPVIVAAFTRK -LRD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces carpinensis TaxID=66369 RepID=UPI000A364D54 ------DRIRAAFADAGVTGRLHALDIDSAAQL-GVDADQLVCTASVHKLCLLVALHDRAA -TGDLDLTEPVECSPDGRTPPTGLAAMLDATRLSLRDLAYLMMAVSDNAAADLLLARV-GL -DAVNRTTARLGLETTRAVHTFGAMLAALDPARTNHSTPRDMTRLLRAVWRDEACPPEHGA -AIRRVMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ARATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P7XFB1_9BACT --dDLRTSIQEVIDNINGSIAVAYVNLDHGDTL-YINADRMYHAASTMKTPVMIEAYRQAY -DGGITIMDSVYVHNESIVDGSLYSHDQIGSYVPMRDVIYNMTILSGNLATNLVIDIV-GA -EHVMRTMRELGADNIEVLRGVEDMLA-FQNGMNNRTSARDLAILFEHLARGSAVSPEMDG -DMIAILKDQEF-RSMIPAGLPDNAVVAHKTGSIT-GINHDSGIVYLPDGRSYVLVILTGD -LE-NNEDGIQAGAEISRIIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3M1PD89_9BACT ----LQARLERLVEGFRGDVGLYVRHLPTGRYA-ALNADTLFPTASLIKVPILITTFDAIE -RGELAYQQELVYRDSLRYPGEDLLGSFKDGEIALSKVVMLMLTMSDNTASLWLQHLCGTG -TAINAWLAAHGFEHTRVNSRTPGREAARARYGWGQTTPREMAELLVMIREGRAVSPAASE -EMYRTLTRTYW-DDEALSQLPPTVQAASKQGAVSR-SRSEVVLVNAPHGD-YVFAVITKN -QEDPDNEGFVLLRDVSRLLWHYf ->[subseq from] serine hydrolase n=1 Tax=Oscillatoriales cyanobacterium MTP1 TaxID=1751289 RepID=UPI001300BECF ---AMTRRLQRRLAAFKGKVFCFAKNLDTGETF-GYNPDARVRTASTIKVPIMVEVFAQVA -EGRLRWDDKLTVVRRHEYEGGVLFELTPGTQITVRDAVRLMIVVSDNIATNILLDRI-TT -DAVNDRLAQMGFEHIRSLRKIAGGGEENKKYGIGVATSREMVRLLEGLERGTVVSPEASR -EMLAIMKRQQY-RDGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKHG-RIAMAITVED -IPCSEAEGHLLIADI-------- ->[subseq from] Beta-lactamase n=2 Tax=Sphingobacterium deserti TaxID=1229276 RepID=A0A0B8SZE9_9SPHI --rKLTHNLKDLVAGFEGEIGIYVHHLKSNRTV-EISADSIFPTASIVKVPLLVGVFNKID -SGALKLNANYRYTLEREYGGSGLMQLFKDSAIDLSTMISLMLTYSDNVASIWCQELAGGG -QAINPLMEKLGLNETKVNSRTTGREKLWKQYGWGQTTPREIVKLMTMIRQGEIFSPRLSN -KMYRYLKNQFY-NERSLSQFPAYVATASKTGSVD-AARGEVVFVHGPSGD-FVFAVLTKD -NKDQDNTAEELTRKIANTIWNHf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UKG4_9BACT ---SLASRVSERLKRCDAVMGVAAKSLASGEAV-LVDADRRFPTASAIKTAVMVEVFHQIA -EGRFDRDKEVVLTREEKVDGSGVLQDHAGLRLTVGDLLSLMISVSDNTATNLLVGLV-GT -ASVDRRLEGYGLVDTKLFRPTRDGKADHPELERGMSTPRELVRLMELIAEGRVVSRAACD -EMLALLRAQQF-RTMIPRRLPEGIKVGDKPGWDERHVRIDAGVVETPRT-RYVIAICARQ -VRDTDNDALVTGADVARLIHDDf ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3LVT4_9PSEU -----------VFGGLPGRIGFAAWDLDEREPV-LVDAERVVHAASTIKVLIMITALRAVR -EGRLGLDAEVELPAE-RAGGFGVLRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF -EAIRACAADLGCTATQVQRRLMDVNAP----GRNETTALDQARVLAALAGGSALPPELTE -HALDVLSRQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIG-DDRPRAVVAVLVDE -LTDERSA---------------- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A2E6L0A9_9BACT ---TLATKLETRIAELDGEVGLYVHHLKKDHSV-LINADELFPAASLIKVPILASLLNKVE -RGELGYQDKLIYTKDRLYPGEDLLGSFANNELTLKKLVFLMITTSDNTASLWCQELAGTG -TTINTWLKQKGFLHTRLNSRTPGRADARDRYGRGQTTPREMAQLLIRIRNRKLVSPAADE -EMARIMGRSYWDGEAI-SSVPPSVSTMSKQGAVN-ASRSEVVLVHAPHGD-YVFCVITKN -QKKHGNEGFSLLRDISRILWEHf ->[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=UPI000B8509DF -----------VFGGLPGRIGFAAWDLDEREPV-LVDAERVVHAASTIKVLIMITALRAVR -EGRLGLDAEVELPAE-RAGGFGVLRELPSVTISLRDLITLMIVISDNAATNAVIDAV-GF -EAIRACAADLGCTATQVQRRLMDVNAP----GRNETTALDQARVLAALAGGSALPPELTE -HALDVLSRQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIG-DDRPRAVVAVLVDE -LTDERSA---------------- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. 1G10 TaxID=2025605 RepID=UPI000B982C78 ---KLSQSWKALAAEHDLKVGGFLLVLDDGRFA-QLNPDIPLPAASSIKTPILLAALDDLD -AGKLRWNEPLPLTKEVMGGGAGWMASRPGTRFPFYEAATEMIRVSDNTATNLLIKRLGGK -AATNAHFQALGLPSTVINNWLPDLEGT------NTTSPRDLARSIALVDIGEKLSPRARD -HFRTIMATSRT-NTLLPAGLLKGLTVLNKTGDIGI-AYADAGLIELPNGKRAVAGFMVKG -PFND-PRSTDLIRAMAAAVSQ-- ->[subseq from] serine hydrolase n=1 Tax=Paenalcaligenes suwonensis TaxID=1202713 RepID=UPI00140D34B3 ---QLESSLTPLLEKEPARISMAVRTLDGVSLF-DWHVQRAMPSASLIKVPMLLCLLEEVA -KGRVSLDDIRALPDSNRAGGTGILSQLPGVQLSLRELAHLMIVLSDNVATNALIDVL-GM -DRINQWCRQAGLAYTELQRHMMDAQAR-AQGKDNWTSAADACTTLLYLLQSPVLPEALRH -EGLQMLADQRE-RGHFAATLPADVELAHKTGSLP-GLRHDAGVMTVGKR-SVVLAVLADG -FT-DARTS--------------- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium drakei TaxID=332101 RepID=A0A2U8DRK9_9CLOT -----EELLKNSLKNSESKYSLAVKNLKSKEIC-YMNVHEVVPSASIIKLFIMAEAFNENK -MRKLDLHDIIKINNDKKVPFSIVSLLNSVEQYSIKDLITLMIIQSDNTAANVLIDFL-GI -DNINNFIKETGFKNTILGRKMMDFEGD-KGGKDNYTSAYDVFLFLEKLYNHNLVGEKEDK -FMIDILSHQLD-FSMMRIDMLDDLKIAHKTGDLNC-LKHDAGIVYSEKVGDYIFVMFTYE -AQ-SDGYARKLICKTSKQIYNYf ->[subseq from] Serine hydrolase n=1 Tax=Niabella ginsenosidivorans TaxID=1176587 RepID=A0A1A9I322_9BACT --kKLKVLIENAISGFHGDIGVYVHHLKKNTSV-AVNADTIFPTASIVKVPILTGVFNKIA -QKELKLSQEFVYDAKRAYGGSGLMQFYKDSATDLSTMISLMLSYSDNVAAIWLQELAGGG -AAINPLMDQLGLRNTKVNSRTEGRQDLWKKYGWGQTTPREMAQLFTLIRQGKVIDARYSD -KMYRYLKNQFY-NGRSLSQIPATVNTICKTGSIDD-ARGEVVLVNAPGGD-YVFCILTKN -NKTDDNEAEVLTRKLSNIIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium BR5-29 TaxID=2607284 RepID=A0A5J5IF05_9BACT --kKLENKLHALIDSFHGTAGIYVRNLKTGKEV-AINADTIFPTASIVKLPILIGIFNKIE -EGEFTYHQPMLYRDSMAHGGSGLMQYFKDSSTDLSNVITLMITHSDNTAAIWCEKLAGGG -LTINEWLTEHGFQSTRLNSRTPGRKNNYDEYGWGQTTPREMADLLVMIRQGKAVTPAASE -RMYRILTHVYW-DDYALSKIPPYVQVASKQGMVD-ASRSEAVLVNAPHGD-YVFYIATKN -NVEPGNEAWQLARKVSALIWNYf ->[subseq from] serine hydrolase n=1 Tax=Deinococcus reticulitermitis TaxID=856736 RepID=UPI000B860DA3 ------------ARGYAGTAGLVVLDLQTGETLyEEHADRPFPAASTIKVPLLVLALQAAE -RGELVLTGRVTLQAEDRVPGAGVLHELEPGLLSWRDVLTLMIVVSDNTATNLLIEQL-GL -EACNAGFRALGLRATRLVGPLERRNAAQRRGERNRTSAREQAGLLRQLGRGDLLGPEHTG -WAQDVLFRQQV-RPLIGRGVPADYRLASKSGELR-GVQHDVALLHTP--RPLAVALLSEG -GTDPREHP--------------- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013B69F65 ----LGEQLAGLAAESPGTWAFAVRE--QGRAVaSVRGDVVVPAASTIKVALMVLALQDVE -AERCRLDSVLRVP-DERVGGSGVLRLLPSVRLRLDETLELMIGISDNTAANMVIGML-GV -DDVARRVAALGARNTRLERRLMDLEAA-RQGRDNVTTADDQALLLDLLAGETVLSVELRQ -HALEILGRQQV-NDRMPAALGPDVVCRHKTGELE-GVRHDVGLLEFDGRQ-VAFAALGTD -LPEQAAPAGSVIAGAARMVVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Halopolyspora algeriensis TaxID=1500506 RepID=A0A368VDY0_9ACTN -------------DGFPGRVSVAAWALDESDTV-TVQAHRPVQAASTIKVLVLITALRHVR -DGRLALDTELPLPAEHRVGGTGVLRELASVSLALADLLALMIVVSDNTATGVVIDAV-GF -DAINACARDLGCTTTRVQRHLMDIDAMIDG-WDNVTSALDQARVLDRLARGTALPDELTH -WALDVLSRQQM-RDRLPALLPVGAECWNKTGEQI-GLRHDVGLIGRAGKPQAVIAVLVDQ -LTD-------------------- ->[subseq from] Beta-lactamase n=2 Tax=Lactobacillus TaxID=1578 RepID=A0A0R1WQ18_9LACO --------------NISGKSSIYVTTAKSNQSY-SVNN-RPQLSASVIKLFILGAAFMEAN -DNHLNLNDSYILKDSDKVGGTGILQNKPNGTYTYRQLLTYMIDFSDNTATNIIIDKLGGV -ERTNFLISKFNVKNTKLQRKMMNFNAK----KDNYTSAEDTALFLKQLYNHQLLSKSSDE -EMLKILKQNTD-HSKLLKNLPASTVTYNKTGINDQGIQNDAAIISNKNGA-IIVVVLSEK -GNSS--QQ--------------- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A359KR52_9CHLR ---ALQSTIDSLMAGVSGVTAVEIENPDGSMLA-AWNAGEQIEAASLYKLGIMVETYRQRD -AGMLTFDDQIVLQDYHFSEGSDVFSEEVGMTTDVGTLLQAMITVSSNVAATALLEYV-GT -DNVNATMASLGLSSTVI-RWYPGPSGVRANAAMNVTSAADMASLFRMLLAGEVVDAEASR -EMLDLLARQEI-NDRLPAYLPDGTVVAHKTGNLD-GLMHDAGIIYAPTG-PVIVVVMTED -VD--DAASTDLIAQIGLLAYET- ->[subseq from] Beta-lactamase class A n=1 Tax=[Clostridium] celerecrescens 18A TaxID=1286362 RepID=A0A2M8ZC42_9FIRM --------IIKKLERVPGKISFFYEDLKTGKVF-AYHEQEPMMAASIIKLFVMAAAFEKSK -KGTFQMDELFAVKREDWVPCGALTYLHDGILVTGLDLITLMIIFSDNTATNILIDIL-GI -EEINEMIRELGFRHTLLQRKMYDVERS-SRGIQNYITADETGRLLKMMYEGTLIDRQSSE -AMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEVSLELYN-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3M2D4S7_9BACT --eSLDERIKKEIAGFQGSVYIYAKNIDNGKTY-ELRADERVRTASTIKLPIMVEVFAQVA -EGKLKWDEKFVLKN--KISGSGILGEFTEGTLDLKTLVNLMIVVSDNTATNMILDRI-TT -DAVNERMEKLGFQHIRSLRKIGGGGEAKIIDEGGVATMREMGRLLEMIERKEIISKEACK -EMIEILRRQQY-TDGLGRGLLETTPIASKSGTLDR-LRSDVGIIYTRKGR-IVMAITVDD ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Deinococcus marmoris TaxID=249408 RepID=A0A1U7P1H9_9DEIO -------------QGYVGEIGLRVCDLTGRELF-ALNPERVFPAASTIKVPLLILALAWAQ -AGRLDLESRVTLEATDRVSGAGVLHELGPGLLSWRDVLTLMIIVSDNTATNLVIGRL-GV -EAVNDWLTAHGWTETRLVGKLQQRNAAQLRGERNRTTAADQTDLLGRLVRGELLDAAHTA -LALDILERQQF-RDLIGRGLPRAYRLASKSGELD-GVHHDVGVLYTP--RPLVIALLTGG -GT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter sp. T436 TaxID=1729720 RepID=A0A1L6R3E9_9FLAO ----LEQKLEELTASFKGDVGVYVKHLKTGKEA-AINADSIFPTASIVKVPILVKIFDKIE -EGELSYRDSLVYSEDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -EAINKLMTELGLEHTRVNSRTEGRDKDWEKYGWGQTTPREMASILEQIRKRELVSAAASD -EMYRLLGNSFY-QDYALSQVPPYIQVAAKQGMVNK-SRSELFMVNGPSGD-YVCYIATKN -NEDEDNEAWQLQREISNLLWNYf ->[subseq from] ClassA (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLL1_9BACT ------------------------------------------------------------- --------------------YSPLREARPEGNITIGELLKYSVALSDNNACDILIDYLGGT -SALQKYVRRQGIKQMKITATEDRMHKS-GDPYLNHTRPSSAVRLLEKFIQQELLSPVYQK -FLEDTMIATSTGSDKLKGLLPAETIIGHKTGSSDKAGDNDMGFVYLPHGDHYTIAVFITD -SMEDDKTNAAIIAQISKAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. H33E-04 TaxID=2703787 RepID=A0A6B9ZCG6_9BACT --rKLEKGLRDIIAGFQGDVGIYVRNLKTGRYV-DINADTIFPTASIVKVPILVGVFDKIE -KGELTYHQPLIYRDSIKYGGSGLMQFFKDSTTELSVLLALMMSYSDNTTSLWNQALAGGG -QRINELMAQYGLTVTRVNSRTPGREAFRTTYGWGMTTPREMAELVVKIRNGAVISKDASA -RMYRLMSHGYY-DETGLSQIPPYVQAVHKTGSVD-ASRSEVILVNAPHGE-YVFYVGTKN -NKTDDNEAEKLIIKISGYLWKYy ->[subseq from] Serine hydrolase n=1 Tax=Antarcticibacterium flavum TaxID=2058175 RepID=A0A5B7X4H3_9FLAO ---NLEGQLEQLLSNFNGTAGVYVYNIATGKEA-AINADTIFPTASVIKVPILVTLFNKIQ -EGQLHLNDSLVYTEDRIYGGSGLMQFYKDSTTDLRTLAALMITYSDNVTSLWSQELAGGG -EEINRFMESLGLEDTRVNSRTKGREEIWKKYGWGQTTPREMVSILVKIRNRELINEAASD -EMYRMLTNSFY-TEYALSQIPPYVQTAAKQGMVNR-SRSELVMVNAPGGD-YVFYIATKD -NED-------------------- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034) TaxID=485918 RepID=C7PH33_CHIPD --rKLEKGLRAIITGFQGDVGIYVRNLKTGRYV-DINADTIFPTASIVKVPILVGVFDKIE -KGELSYHQPLMYRDSIKYGGSGLMQFFKDSTTDLSVLVALMMAYSDNTTSLWNQALAGGG -QRINELMAQYGLNNTRVNSRTPGREAIRNVYGWGMTTPREMSELLVKIRKGEVISENASS -RMYRLMTHGYY-DEVGLSQIPPYTQAAHKSGSVD-ASRSEVILVNAPHGE-YVFYVGTKN -NKTNENEAENLIRKVSAYLWDYy ->[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium TaxID=2044939 RepID=A0A2V2FD76_9FIRM -------------SRVPGDVGFYFKDLTTGEEL-GRNENEMFQAASVIKLPMFAVVAKFVA -EGKASWEDRLVAHNEERVPPCGALWFFEDEPVRLKTLCGLMITISDNMATNMIMRHF-GI -ETFNREFREIGLEKTHIERLLFDSAAG-AQGKQNKIVPREMGCLLERVYRHSFVNETVSK -CIEDTLLEQQI-NHKIPGYLRGEVDVAHKTGEDD-GITNDVGIVYA--REPFVICFATNN -TD--VPEAERAMREISLALAD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces parvulus TaxID=146923 RepID=A0A191V0L9_9ACTN ------ARLDAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHERAA -AGALDLTEQVECPPAGRTPGPTGLSAMLDPVMSLRDAAFWMMSVSDNTAADLLLRRV-GL -DAVNRTAERLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium CG12_big_fil_rev_8_21_14_0_65_60_17 TaxID=1973924 RepID=A0A2H0JNL2_9BACT ----LEEQLSERLESLDGTSGLYLRHLPTGREI-SIRADSVYPTASMIKVTILAALVDRVE -RGELAWTEKLVYRDSLFYSDADITGELQDGAVSLDMLARLMTSYSDNTASLWLQELAGTG -VAINAWLASEGFETTRMNSRTPGRRSDWEAYGWGQTSPREMAQLMVMIAEGRAVSPAASD -RMLRLLSGSYW-DGEMLSVLPPGVEVASKQGAVS-ASKSEVVFVHAPGGA-YVLCVITNK -QTAQDNEGYVLLRDVSRLVWE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Bacillus TaxID=1386 RepID=A0A366JKJ7_BACFI --hTLKAEILDLASCCEGHVAVYIH---TGDGViETNADDVISSASLIKVPILLAGLSQAE -NNLLQLDEEAEVNDTVRVGGAGVLQAMSKDLVKVIDLMTLMVIVSDNTATNLIIERL-GI -EKINQLIKGLGFNCTELNRKMMDFE-ALKNGMDNITTARDMVYGMKALAEHSLLSGKYTE -KALDILEKQQYKNKLANTIDTEKVKVASKTGELP-GIEHDCAIFTYKGN-TVYAAVLVDQ -LQ-SQAAGGEVLAAIGSRI---- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7Z511_9BACT ---DLESRIREEVAHFHGTMGVVARNLDTGERI-SVNGDMRFPTASLIKVAVMVEVFHGFA -DGSLRRDQTVTLSDADRAGTVPLNVLHAGAVLTVSDLLRLMIAWSDNTATNLLVRLA-GI -VRTNRRMEAYGLANTKIFRPTRDGKAVFPELERGMTTPAEAARLFESIAEGKAVDRAASD -EMLAILALQQD-RAMIPRRLPDRIFVASKTGWDEEKVRNDAAYVKGPRG-RYVLAILVRR -GKDKDSEALVTGARISRMVYDAf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E4I1Y8_9BACT ---SLEETVEKQLQSLDAETSFYAKHLPSGKEI-SIRADQPMNPLSVIKIPMMILAFQDTE -NGQFDLDQRYHIRAEDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNKL-TM -ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD -EMTNILKRQFY-SSRIPRFLRGKATVGHKTGDWPPHAGNDVAILYYDGG-PSIMAIFTNQ -NKGDFVELESTIGRIAEELVSRw ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7D630_9PLAN ------DELDAVAKKFDGRIGFFVRGLASGADY-GWNSDERFPPASVIKLPVMIELYRQAA -DGRLDLDKKLRLPDDISTHGTGVLKKKKRPVLPLREYADLMMIHSDNMATDFIIRTV-SP -TATNRFLDVQGFRNTRVALELGRWHYYSDSLKNNVCAPREIVLLLERLYNGELTSEKNKQ -AILEPMRASTH-KNTIARHVKRGIQVANKYGGSQR-IAADAGIIEIPDR-PIAIACFALA -NDPTDRSGRDILAEMCRLAIK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=A0A1I5GLG6_9FIRM --------------KDGAEISLLVKDFKTQDILySHEDTKEVVSASIIKVPIMLTALEQVQ -KGKLELDSLIELKDAGILEDTEVFE-YGGGKYTLEELLVWMIIESDNTATNCLIDLL-SM -ETINTFCKKHSLKSTKLERRMLDFQAV-QEGRNNYTSAGDMAILYEELYNRTILTPDLCN -TALGILKRQRH-KQLSLRYIYDDITVAHKTGSLDN-LDHDAGIFYLPNIQ-YYFGAFVWN -AP-SNEYASKWIGRISKGIYEYy ->[subseq from] serine hydrolase n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=UPI00132FAB33 ------------------------------------------------------------- ------------------------------------------------------------- ----------MGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQ -QLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPAGKPSRIVVIYTTG -SQATMDERNRQIAEIGASLIKHw ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus formosus TaxID=54913 RepID=A0A220MJX4_9BACL ---ELENRLSAIIGQAEGTWGVVVEELGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -TQIDQTMIDLGMRQSYYSRKLMIYPLD--ITENNMITAGDVASMLGHLATGSYLSRRACK -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKN -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Beta-lactamase class A (Fragment) n=1 Tax=Microgenomates group bacterium LiPW_16 TaxID=2017212 RepID=A0A554IBL7_9BACT ---NLLNEIKKIIDKSPGSWSIYVYDLTTNQGF-GINETAIFTAASVNKVPILAVLYHLTD -KGEIDLDQQVTLQASDIQNTGSIRYDPPGTTYSLKTLARLMMEKSDNTAAHLLGRQIIGF -DKIQELLDAWGLTQTNMEE--------------NKTSLGDLLKLFLKIYRGELAGQALTA -EMIGFMDDSDF-EDRIPALLPKGTKVYHKIGDEV-GNIHDVGIVELDKGT-YFIGVLTSD -IV-DELAAKKTIAQISKLVFKY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4FV38_9BACT -----QRLLDAELARIPGTAGVWVKHLTTGEEA-AVNADRVFNSASVIKIPVMLLAFQLAD -QGKLSLTERITIQAADVRGGSGVFRYHDAGLPTLRDVLLQMIITSDNTATDLAIGKVGGI -GPVNAMIKRAGYDPLQLTMTTGELFANDPAFWLGSMTPRATGRMLEDIQRCSVASKAACA -DMLQMFRAQQSGARRLPHFLA--VPVGHKTGDFPPVLANDVGIIYARSG-PIVVAFFLNG -IRGSYAEAEDHIGRVAQLIVEYf ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4V2APD1_9BACT --kKLERQVQELIKGFNGDIGVYIKNLENGRTV-AINADTVFPTASMVKIPILIGVMDKIN -RGELTYHQSLTYKDSLLYAGVDILGSFKNDEIDMSKVMMLMLTTSDNTASLWLQSLAGKG -TRINELLDSMGFVATRVNSRTPGREAIRSIYGWGQTSPREMATLMEKIANGEIISKERSA -QMLRLLGRNYWDDNAI-SQIPSDVFVASKNGAVNE-SRSEVLFVNGR-GARYVFCICTKN -IKQPGNEAWVLTRNLSKLLWEHf ->[subseq from] Beta-lactamase n=1 Tax=Rufibacter sp. DG15C TaxID=1379909 RepID=A0A127B1R9_9BACT --kKLTQKLEALTKGFQGEVGIYVKHLKTGKTV-AINADTLFPTASMIKVPIMVGVFNKIE -RGELDPKAILQYRDSLLYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQHLAGTG -TAINQWLESNGFQDTRMNSRTPGRRPNWEKYGWGQTTPREMATLLTMIREGRAVSPAASE -RMYRNLGRIYY-DAEALSQIPPYVHTASKSGAVNQ-SRSEVVLVNAPHGD-YVFCIITKN -QKERSNAGFTLIREVSKVLWQHf ->[subseq from] Uncharacterized protein n=1 Tax=Halobacillus karajensis TaxID=195088 RepID=A0A024P480_9BACI ------VSIAKLAANVDAEVSIFIRY--GDHSV-RINEDCVLPAASTIKIPILMEAFRQRD -EEMIDFSERISISPKDRVGGDGVLSLLIESAMEFEDLLTLMIVVSDNTASNILMDEL-GI -SAINDLCQSLGCPSTKIRRLFMDFDA-MQAGINNTTTASDMMRLITALDQGKIGGKSGAT -QMIEILQHQRY-TSGLPAYMTSNIKFATKTGQLP-GICHDLGIFKYREQK-VYAVVMFHQ -LA-EGEAGRRALGDIGKVI---- ->[subseq from] serine hydrolase n=1 Tax=Halobacillus karajensis TaxID=195088 RepID=UPI0008A786DC ------VSIAKLAANVDAEVSIFIRY--GDHSV-RINEDCVLPAASTIKIPILMEAFRQRD -EEMIDFSERISISPKDRVGGDGVLSLLTESAMEFEDLLTLMIVVSDNTASNILMDEL-GI -SAINDLCQSLGCPSTKIRRLFMDFDA-MQAGINNTTTASDMMRLITALDQGKIGGKSGAT -QMIEILQHQRY-TSGLPAYMTSNIKFATKTGQLP-GICHDLGIFKYREQK-VYAVVMFHQ -LA-EGEAGRRALGDIGKVI---- ->[subseq from] Serine hydrolase n=2 Tax=Synechococcales TaxID=1890424 RepID=A0A358C000_9CYAN ----LSKRFSQLAAAQNLKAGAFVLVLDTGSYA-QLNADTPLPAASAIKTPILLAAFEAID -QGKAKLNEKLTISKVVVGGGSGWMGSQPLGSFSFNEVATEMIRVSDNTATNLLIQRLGGK -TALNAKFLQLGLTGTAIKNWLPDLDGT------NTSTPRDQARTIALVETGKELSPRSRD -LFRSTLGSSRT-DTLIPTGWLQGVRVFNKTGDIGI-AYVDSGLIELADGRRAVASYMVKG -PFND-PRSTDLIRAMAAAT---- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans KG-16 TaxID=1441730 RepID=A0A0V9UKM9_9NOCA -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQQRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TAVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATTPAEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQIW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus onubensis TaxID=1571209 RepID=UPI000C0C08C3 ---NLRLSIDSLLEDFSGSISLEVRSRQGDKII-SYNENEVFPTASTIKVFILGAMLEQVQ -NDQYSLTDLIEMRAGDQVGGSGVIKEFTPGSYPIRDVATAMIILSDNTATNMILELVGGI -DVVNTHIKKYGYTYTELRNIIDF-Q-AIGEDVENVSTSAEFVDYLEKILNNKILKPEIKD -VMIDIMARQQY-LDLFPRYIPQDIQIANKTGFFM-GVRCDVGYIFIKNKQ-YVFTVFSKN -CANPENEAAVLIGKLGKEI---- ->[subseq from] Uncharacterized protein n=1 Tax=Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10) TaxID=1817868 RepID=A0A1F6C8H9_HANXR --dELLRKIVEVGRERRGTVGVAARRLDSGEEV-RYEAEGEYPTASVIKLPILVALYRKAA -EGKLDLDERMTPKPEHYMTGTGVLNDLSRDILSLRDLARLMIIVSDNVATNLIIDLV-GR -AYINEAMQEYGLKDTAVRQRLDYISKAWPDFRRAISSPSDLVLLLSKLSRREILTPEACD -EVIDTLIRNQY-QEMLPRHLPRVLWVADKPGMLWD-VRADAGLVATPGL-TYAVAIMLYG -IKGEDTDGAHIVARLSRLIYDYf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces eurocidicus TaxID=66423 RepID=A0A2N8NUE4_STREU -----RGRVRAAFAEAGVTGWLHAVDIDSGAQL-DAGADQPVVTASVHKLCLLVALHQQAE -AGRLDLSEQTTCPPRDRTPGPTGLAAMLDDVLSLRDAAYLMMAVSDNTAADLILERV-GL -DAVNRTTWRLGLTGTHAVHTFREFLTVLDPAATNHSTPRDMTRLLAAIWRDEACAPEHTA -AMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -SSAVLPPADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces leeuwenhoekii TaxID=1437453 RepID=A0A0F7VLS6_9ACTN ---SIARRIGAAFAEAGVTGHLHAVDIDSGAEV-DAGADQPVVTASVHKLCLLVALHEQAE -AGRLDLAERVECPADDRTSGPTGLAAMLDPVISLRDLAYLMMAVSDNGAADLLLRRV-GL -DAVNATTARLGLERTCALHTFRELFAALDPARTNHTTPRDMTRLLGAVWRDEACLPGHCA -AMRRILGLQVW-PHRLASGFPDDVRVSGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRS -ASATLPAADAVIGTAARMAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus wulumuqiensis TaxID=980427 RepID=A0A345IJR4_9DEIO --------------GYAGEVGLLVTDFGGRELY-ACAADAPFASASTIKLPLLLMALEQAG -RGDLDLAERVTLRAEDRVPGAGVLHELSPGLLTWQDVLTLMIVVSDNTATNLLIERL-GQ -DDFNAWLTARGLTRTRLVGPLERQNAAQRRGERNRTSARDQVALLLSLLRGDGLTPQMQQ -LGLDILGRQHL-RDLIGRGVPAGYRVASKSGELR-GVHHDVGLLWTP--RPLVVALLSQG -GED--PREHPANRDVTRLAA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ferruginea TaxID=53367 RepID=A0A3D9ZTG3_9ACTN ----LTARLQAIVASAPVTAGVSVRDLSGDQQI-SVAGRFRPKAASLIKLWVLVELMRRID -CGQAAYTDGVLVLPEDVVGGTGELQHETFPQVTLFRLAQYMIKYSDNTATNVLIDYLGGF -EPVNALIDSMNQRETVLGRKMLATP-----PPENFTSPDDVISLLGAVWDRQVLRQVNRD -LMLSFMLEQTL-NGKIPAALPSGVPVAHKTGELPD-VSHDVGYYLIPGT-EIAVAFLTAG -VE---TEGAETVRQLARAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0009E34FDA ----LREEMMGVVQECSGKVSFSVLF--DDESL-SWEEDRRISSASLIKLPILMAAYEQIQ -TGRLQADAMIVLRHEDHEEGAGVLNGHDGLTLSIEDLLTLMITVSDNTATNRLIELI-GM -DFINRFCLDWNLKGTFLNRKMMDFPS-LEMGKDNWTSSEDVVSCLTLINEGPF-EEASRK -KMLTMLSRQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCAIIESASGKYAYVAVLTDE -LPAP-EEGRRVIRTVGKLIGD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus hilgardii TaxID=1588 RepID=UPI00019C520A ---------SQCVAASSGKTSIYVSELDSKNSV--VENNRVQRSASVIKIFIMIEAFRQIK -AGQLTLNQQVIIPADDRVGGTGELANQNTHQLSVKQLLRLMIRNSDNTATNVLIDKLGGL -AVINAEINRLGCSHTKLRRKMLDYR-ALQNGKDNVTSVSDLGKTLMALSGHRLLGHPYDS -EMLQLLRYNSN-QSKLSALISRKAVIYNKTGEFDYGVQNDAAIVKKGKRA-FVVVVLSEN -GTQQ--KQINAMQMLGKR----- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura geliboluensis TaxID=882440 RepID=A0A5S4GSC9_9ACTN ------RRIEEEFRSAGVTGVLHVVDIDTGREV-AIGAAEPVVLASVFKVPLLVAFHRLAA -AGALDPAEQVTLRPQDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADTVLDRVGGR -DAVNAAAAALGLRDTVVEVTGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPAADCA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLLT-VRNEVGAVEYPDGARYAVAIFTRS -PTAVLPRADAVIGTTARLAIE-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. CL-2 TaxID=1499684 RepID=UPI0009DC99CF -------RVAQKLSAYNFNYSILFKNLTSLETI-TWCEKATFPSASTIKIFIAIEAFNQIN -KELIFEDDIILLDDTMKVGGSGILSSYSNNSISIKKLIYLMMAESDNTATNILIDIL-DI -NNINTTINKLLCKNSALNRKMMDFDS-IKKGIDNYTSALDLAIVLERLYTNSCINKKYDT -LILNIMKDCTN-NSKIPSKLPSHIKISHKTGELDY-IENDAGIIFTPYGD-YILIILTEG -YNNS--VEIEAISEISKIIYDSy ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus modestisalitolerans TaxID=1457219 RepID=UPI0010F67A32 ---QVRADINNTIAPLSGDSEVYVTPVKGSQQV-SVNNGSQ-RSASTIKIFILVTAYALEK -EGAFDLNDEYTISDDDKVGGTGVMRTMADGTLTYHEVLTHMIADSDNMAANVMIDALGGF -KLINNKIESLGATDTQLNRKMMDTD-ALEDGDDNVTSAEDLGQTLKKMYNHKLVSADADR -AMLTILAQNHN-RTKLPHDLPGDATVYNKTGEFDYGVQNDAAIMANKRGA-FVVVVLSQD -GQQTEQ--V-------------- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FF8E520 ---QIKDDISSTVGSINGTNSVYVSPVDSKQTV-LVNNG-SQRSASSIKIFIMVTAYAMAK -EGVFNLDDTHTVSDSEKVGGTGVIQNMDAGTLSYQEIIAHMIDDSDNTAANIMIEKLGGF -QLINTKIKNMGATDTKLRRKMMDTK-ALDAGRDNTTSARDMGATLKKIYNHQLVSQQADD -AMLTILSKNQN-HNKLPKQVPSSATIYNKTGEYDYGVQNDAEIVKNSRGA-FVAVVLSED -GEETD--QVDAM----------- ->[subseq from] serine hydrolase n=1 Tax=Pseudoflavitalea sp. X16 TaxID=2716334 RepID=UPI00141E9F1F --rKLQEKITALIQAQRGVVGVYVKNLRTGKVA-EFQADSLFPTASMVKVPILVGVMDKIE -KGELPYNQPLEYKDSLLYAGEDILGSFKSGEIELSKVMMLMLTMSDNTASLWLQSLAGTG -ARINELLDSLGLQFTRVNSRTPGREENRKQYGWGQTTPREMTTLMEKIYRGEVISKKASE -RMLRVLGRNYHDVNGI-SQVPPYVFVASKTGEVNQ-SRNETLLVMAPHG-PYVYTISTKK -LENPSNEGWVLCRKLSALLWHY- ->[subseq from] Serine hydrolase n=1 Tax=Cytophagaceae bacterium BCCC1 TaxID=2015573 RepID=A0A257IZ60_9BACT ---RLKDQIIELMSKTEGDFGLAFKNLENSDTI-FINAHEYFHAASTMKTPVMLEIFKQEK -QGKFKISDSIIVQNESIVDKSRYSYRKIGQKMTIHDLTYEMMTKSSNLATNILIDKV-GA -KNVMKLLSSLNIKENIVLRGVEDQK-AFEAGLNNKTTPFGLMQIFEHI----ALTQSRNS -LMMEILFEQKF-NEIIPAQLPKTVKVAHKTGSIT-GVQHDSGIVFLPDGRKYVLILLSKN -LK-NADDGVKTLAVISKLIYDH- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. HV4-5-A1G TaxID=2004595 RepID=A0A5M9NRY4_9CLOT -----------KVGKLKGKVGFCYKDLDSGDSF-GVNEDEPFIAASIIKIPILIEAYRQFR -EKILFKEELVEIKESDRVPSCGAAAYHPGARLMLKDLCVLMIVLSDNMAANILIKKL-KM -SNINNTMKQLGMKKTKVNRILFDSDA-EKAGKQNYFAPDEILKLFEMMWKGSLISRQDSE -DMIKIFKLQQI-NYKMPYLLSEDICVAHKTGDDE-GITHDAGIVYA--RKPFILCFASNE -TD--VNETDEFIRKTTREIFE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A4Y5R2G0_ECOLX ------------------------------------------------------------- ---------------------APIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQLSETSQA -LLWKWMVETTTGPERLKGLLPAGTVVAHKTGTSGTAATNDLGIILLPDGRPLLVAVFVKD -SAES------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces shenzhenensis TaxID=943815 RepID=A0A3M0I8B8_9ACTN ----VPARIHAAFAEAGVTGRLHALDIDSGAQL-DVGADQPVCTASVHKLCLLVALHEQAA -AGRLDLGEQVECPPAGRTAGSTGLAAMLDSALSLRDIAYLMMAVSDNAAADLLLHRV-GL -DAVNRTTARLGLTRTHAVHTFGDLLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AVRRLLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -PNATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E4RKW1_9BACT --dSLEERIVGLLDSEKGEFAVAYKNLSTGETI-LINENEEFHAASTMKTPVMIEAFKXXX -EGLISLDDSILIKNESIVDGSIFKYEKIGSYLTLKELIYDMITISSNFATNLVIDYI-GT -KEXNNTMRXLGANNINVLRGVEDIKA-FNNGMNXTTTAXDLLKIYENLAEGNVISSDISD -EMINILKNQKY-DDIXPKYLPKSVEVAXKDGWIS-GVRHDSGIIFLEXNKKYVLVXLSKK -LENE-IXGADXLAKISLEIY--- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium alkalisoli TaxID=1874115 RepID=A0A4U0H1U2_9SPHI --kKLEDKLNNEIQHFKGEIGIYIQHIRSNRYV-AIHADTIFPTASIVKIPILVGVFQKIA -DGQLQVNQAFRYDKNRVYGGSGLMQFYKDSATDLSTMISLMLSYSDNVASLWLQELAGGG -TVINPLLEKLGLQHTKINSRTPGREDIWKKYGWGQTTPREMATLFLSIRNGQVIDKRHSD -KMYRYLKNQFY-NGRSLSQIPSHINTISKTGSVND-ARGEVVLVNAPSGD-YVFCILTKN -NENDQNEAEVLTRKISNIIWNHf ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Heliorestis convoluta TaxID=356322 RepID=A0A5Q2MZT4_9FIRM --sQLEQKIKSYLYRFSGTYGLYVEDLATGATL-EINADKSFPAASVIKVPLILFLYSLAI -DDRIDLDEEMVLEAGDIESGTGILKTAVGTTYTLRQLAQYTIEYSDNSATNMLMRRL-GR -ENFYFFLRLMGAEIIPLGPG-----------KGNIMCARDAALYLKGVMALRELHPEYGQ -EVLQYLLNSKF-DDRIPAGIPKGIQVANKIGTQVN-VVNDAAIVLLN-GKPYVIAILCSH -IHE--QEAVGAIAQISKLVFEY- ->[subseq from] Serine hydrolase n=1 Tax=Cytophagia bacterium TaxID=2026730 RepID=A0A2E5GTU4_9BACT ----LEEEIIYKFENFEGDFALAYKDLSSGNQI-LYNEKQIFHAAXTMKTPLMIEVFNQVN -KNXFNLSDSIFIINQSIVDDSFFSYESLGKKKSIYSLVFDMITVSSNFATNLIIDYV-GA -ENVNKTMRKIGAMDINVLRGVEDIKA-FEKGLNNTTNAYDLMIIYEKLAKGEIINKSSSE -KMIEILLNQKY-KDKIGLYLPKNVKVATKDGIISS-AVHDSGIIFLPDGRKYILVILSKN -LN-DIENASKLIAEISKIIYEY- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter zeae TaxID=2055137 RepID=A0A2N5DD20_9CAUL -heTMSHKLTAIAERAPGDLGVAVQDLTTPQRA-TVAGDHLFPLAGIWTAALGAAVLAEVE -AKALSLRETITIEDVDLSPPSGVADAWPSRRWTVEELLKHAVAGGDNTAADVLMKRIGGP -GAVTAWLDLKKVENLRVDRYARQLLPDYLADPHDSTTPLAAVRFLEALNQAELTSQEGRR -RMLRMMEAAA--GERLRPALPAGARLAAITSATPTAADNVLAMVRLKDGRRFALAILLKA -SPLEEADRDALMLEVTRTVLQ-- ->[subseq from] Putative beta-lactamase n=1 Tax=Lactobacillus pentosus IG1 TaxID=1042160 RepID=G0M5K5_LACPE ---QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK -EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF -DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE -EMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED -GDQ--NDQIDAMNRLGSLLYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces parvulus TaxID=146923 RepID=A0A369VBF4_9ACTN ------ARLDAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHERAA -AGALDLTEQVECPPAGRTPGPTGLSAMLDPVMSLRDAAFWMMSVSDNTAADLLLRRV-GL -DAVNRTAERLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Corallococcus llansteffanensis TaxID=2316731 RepID=A0A3A8PYN5_9DELT ----LNEGVEAAARDFDGALTLYVRDVRTGEEY-AFNASTPMYLSSAIKVAVMLEVLRQVD -TRTLALDRPVVFGPDDVRDMHPLAKVPSGTSLTVAALLDAMMVHSDNAAADLLIGQV-GI -DNVNAGLERRGVRFGPLVSLLEDRRHAYYVEGTNSAPMREVGRLLEQVARCVGLSPAACE -HAKALLRRCDTGRARIRAGLPDTAVWAHKTGTQHR-RACDVGLLEWEHGPSLVVAACARD -FR-RVSDAERLLARLGRTLARAf ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 218-10 TaxID=2486023 RepID=UPI000F78BC7F ------------MGRLKGQNAVYVQQIGHDAYQ-WHV--KSQKAASDIKLFILATVYQQVQ -AGKFNLTATYTLKDGDKVGGTGSLQGMAAGTLTNQELLKYMMTVSDNTATNVVIREVGGF -DAVNREIKRLGATQTVLQRKMMDQKS-LAAGKDNMTSARDLGQLLAKLWQHQLISKSADM -AMLKLMAANTN-HSKLPKLIPSDRQVYNKTGEFDYGVENDAAIFAKGKRA-VVVVALSQG -GP--LAEQVAAMNQLGK------ ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. WMMA1423 TaxID=2591108 RepID=UPI00114729F5 -----PARIQAAFRAAGVTGFLHVVDMDTGREV-AAGADEPVVLASVFKVPLLVAFHRQAA -GGVLDPTEQVVLRPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVMDRV-GL -DAVNATAAELGLRRTVIEGNGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPAGSA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGVVEYPDGARYAVAVFTRS -TLAVLPEADAVIGTAARIAVE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Escherichia coli TaxID=562 RepID=A0A649W0B8_ECOLX ---DVQQKLAELERQSGGRLGVALINTADNSQI-HYRADERFAMCSTSKVMAAAAVLKKSE -SEPNLLNQRVEIKKSDLVNYNPIAEMQVNGTMSLAELSAAALQYSDNVAMNKLIAHVGAP -ASVTAFARQLGDETF--------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Asanoa hainanensis TaxID=560556 RepID=A0A239PBI1_9ACTN ----LAAKLQAIVDAAPVTAGVSVRDLSGEQQV-SVAGRFRPKAASLIKLWVITELMRRID -CGQAAYTDTVLVLPTDVVGGTGELQHTFPQNVTLFRLAQYTIKYSDNTATNVLIDYLGGF -GPVNALADSMNQTETVLARKMLA-----PAPPENFTSPDDVISLLGAVWSGNVLRQVNRD -LLLSFMLEQTL-NSKIPAALPSGVPVAHKTGELVD-VSHDVGYYLIPGT-EIAVAFLTAG -PE---ELGAETVRELARAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. URHB0009 TaxID=1298866 RepID=UPI0004030CE6 ---------------SGARPGIEIV--AGQKHF-KYRAGEKFQAASLIKIPILIEAYRQSE -SGKFSLEDKAVINKDATSGGTGILKALSDGLVTIKDLMTLMITVSDNTAANILIDMI-GI -NELNKSFWEIGLENTVLERKMMDFTS-IEKGKDNFTTAIDIARCLKRVNEENYLSKANKV -DFLRILQMQQF-KSKLPALMDSKMYIGNKTGELPI-VEHDCAILHYGGV-SAYIAVLTDG -FREP-VEAKNAISRIGKHVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522SS50_9BACT --kKLTKELEKTISGFHGTIGVYVWNLKNGKGA-AINADTLFPTASTIKVPIMCALFDKIV -KGGLSYRQPLLYLDSMAHGGSGVMQYFKDSTTDVSVAATLMMSRSDNTAAIWCQSLAGGG -TVINQWLADHGFENTRVNSRTPGRQKIWEIYGWGQTTPKEIADLVVDIREAKILNPAACE -RMYRNMTHQYW-DNVALSQISPYVQTASKGGAVD-AARSEVVLVNAPHGD-YVFAVYTKD -NKTPKNEAEVMIRKISALLWHYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E0H1A9_9CHLR ---SLEETVEKQLQSLDAQTSFYAKHLPSGKEI-SIRADQPMNPLSVIKIPMMILAFQDTE -NGQFDLDQRYRIRAEDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNKL-TM -ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD -EMTNILKRQFY-SSRIPRFLRGKATVGHKTGDWPPHAGNDVAILYYDGG-PSIMAIFTNQ -NKGDFVELESTIGRIAEELVSRw ->[subseq from] serine hydrolase n=1 Tax=unclassified Facklamia TaxID=2622293 RepID=UPI0013BB4D08 --------------NIKGKHQLYFRKVSENTAP-IVYNNQPARSASIIKLYILAVLFEQSE -KGMIDLNSMYSLQAADIVGGTGSIQNAPIGTYSLQQLAKEMIISSDNTATNILINELGGV -QFVNQQIHQMGFKQTQLRRKMLDFK-ALENGIDNETTVIDVGNLLTRLAQGELVSKSASQ -SMLDILEQQHD-HEKLFARMSKDIKVYNKTGTFERGVLADAGIMEYRNH-RYVFVVLSNN -GE--MTQQQQAMQKLG------- ->[subseq from] Beta-lactamase class A n=2 Tax=Microbacterium sp. SLBN-1 TaxID=1489561 RepID=A0A542GV67_9BACI -----REPMMRIVHECPGRVSFSVLT--NDESL-SWEENRQVSSASLIKLPILMAAYEQIQ -TGRLQADAMIGLRHEDHVGGAGVLNGLHEGLLSIEDLLTLMITVSDNTATNRLIDLI-GM -DSINRFCLEWHLKGTFLNRKMMDFRL-LDLGKDNWTSSMDVVSCLKGINEGPF-EETSRK -KMLTMLSHQQF-RDKLPALLGDDVKVFNKTGELP-GVEHDCALMESTSGKTAYVAVLIDE -LQ-DSEDGRRGIRKIGKLVYDY- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus yonginensis TaxID=1054041 RepID=UPI000F7708C9 -----------TMGHLKGQNAVYVQQIGHDAYQ-WHV--KSQKAASDIKLFILATVYQQVQ -AGKFNLTATYTLKDSDKVGGTGSLQGMAAGTLTNQELLKYMMTVSDNTATNVVIREVGGF -DAVNREIKRLGATQTVLQRKMMDQKS-LAAGKDNMTSALDLGQLLVKLWQHQLISKSADT -AMLKLMAANTN-HNKLPKLIPSDRQVYNKTGEFDYGVENDAAIFAKGKQ-AVVVVALSQG -GT--LAEQVAAMNQLGKQ----- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter glacialis TaxID=1259555 RepID=A0A5M8QC68_9BACT --qKLTQKLQALTKDFQGDVGIYVRHLKTGQTV-AINADTLFPTASMIKVPIMVGVFDKME -KGELNPKTILRYRDSLYYAGEDLVGNFKDSSVALGKIQMLSITTSDNTASLWLQHLAGTG -TAINAWLEKNGFQHTRMNSRTPGRRPNWVKYGWGQTTPREMATLVTMIREGKAVSPAASE -RMYRNMGRIYV-DEVALSQIPPYVHTASKQGAVNQ-SRSEVVLVNAPHGD-YVFCIITKN -QKDEHNAGYDLIRAVSKTLWNHf ->[subseq from] serine hydrolase n=1 Tax=Nocardia takedensis TaxID=259390 RepID=UPI0002FF589F ----VEQRIRAVFADAGCTGWLHARRCDSPEEI-TVEGRSRVVTASVYKLPLFVAFCRLVD -VGRLDPRAPLTVVPAECTPPTGLAVLRDPVTMSRRDLATSMMTVSDNAAADVLLGEV-GL -GAVEDLLADLGLTETRVVGGTADQHRAYDPSYTSATTPEEMTRLLRALWSGAVLSVDQTE -FLASVMRRQPW-AHRISSAFPRGVSVAGKTGTIGV-IRNEVAVIEFPDEHPVAVAVFTRA -ARADLPAVDAAIAEAARLAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5NB57_9BACT --eALRQACERIMSESKAAYAVALRDYETDFRF-AIHADRRFHAASTIKVAILLAIGKAID -DERIRPEDTLHVRNRFLSARTPFRHRLVGWTAKISDLAEWMIVSSSNLATNLLLDYI-TV -GEGQRVLREAGVSGVDLRRGVDDKK-AHDQNFNNETTASGLLDLFATL-RGDFLSKASRD -RAINILLQQRF-NSMIPAPLPAHASVAHKTGEIST-ACHDAGIVYLPEREPYILVVLTEV -FSET-NGRREAIAKISEAVFQ-- ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Armatimonadetes TaxID=1042316 RepID=A0A136L201_9BACT --qALKPKLDAISKSFHGRLGYYVKRLDNGEEI-GIRDTERFPSASTIKTAIMVECFRQIE -RGELAWDERLETPPADKRSESMWVAFLAEGVINIDGLIHLMMNVSDNTATVMLADRV-GI -NSIEQLMLSWGLRDTACTIHVDEKDNRQIFANMGVTSPRDMGFLLEQIYRSKAASPAACQ -KMIRILSHQYW-DDFLSYAIPPTVGVASKVGALNR-SRSDSAIVFGP--RPYIVTVYTDH -QKEDDNEGNVAIRRISGLIWNH- ->[subseq from] Uncharacterized protein n=2 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A399XAA6_9BACT --qALKPKLDAISKSFHGRLGYYVKRLDNGEEI-GIRDTERFPSASTIKTAIMVECFRQIE -RGELAWDERLETPPADKRSESMWVAFLAEGVINIDGLIHLMMNVSDNTATVMLADRV-GI -NSIEQLMLSWGLRDTACTIHVDEKDNRQIFANMGVTSPRDMGFLLEQIYRSKAASPAACQ -KMIRILSHQYW-DDFLSYAIPPTVGVASKVGALNR-SRSDSAIVFGP--RPYIVTVYTDH -QKEDDNEGNVAIRRISGLIWNH- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga sp. YR627 TaxID=1881041 RepID=A0A1I5I629_9BACT --rKLEKGLKEIITGFQGEVGIYVRNLKTGRYV-DINADTIFPTASIVKIPILVGVFDKIE -KGELSYHQPLMYRDSIKYGGSGLMQFFKDSTTDLSVLVALMMAYSDNTTSLWNQALAGGG -QRINELMTQYGLNNTRVNSRTPGREAIRNVYGWGMTTPREMSELLVKIRKGEVISENASS -RMYRLMTHGYY-DEVGLSQIPPYTQAAHKSGSVD-ASRSEVILVNAPHGE-YVFYVGTKN -NKTNENEAENLIRKVSAYLWEHy ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium composti Yoo et al. 2007 non Ten et al. 2007 TaxID=415956 RepID=A0A5S5D6N7_9SPHI ---KLEKILQKEIDGFRGEIGIYVHHLGKNTTV-SLNGDTIFPTASIVKVPILVGVFQKVN -QQQLQLSDPFVYDTNRVYGGSGLMQFYKDSATDLSTMVSLMLTYSDNVASIWCQELAGGG -AEINRIMDSLGLKHTKVNSRTPGREDIWKKYGWGQTTPREIAQLMLLIRQGQVFTPRLSD -KMYRYLKNQFY-NERSLSQFPAHIATASKTGSVND-ARGEVVLVHGPSGD-FVFSVLTKN -NKTRDNEAENLTRKIANTLWNYf ->[subseq from] Beta-lactamase n=1 Tax=Hyalangium minutum TaxID=394096 RepID=A0A085WN07_9DELT --------VEEVARDFEGELSLYVLNVEDGESY-AYDADTPTYLSSAIKIMVMLEVLHQVE -LQQLSWDELLELRPDDLRDMHRLGSARPGERLSIATLLEYMMGDSDNAAADLLIRRV-GL -DRVKAQLAARGIQTGPLTSLLEERQRSFYEEKVNSASMRDMGRLLAQVARCEGLSADSCS -RAHQLMRGCRTGRGRIAAGLPKTAAWAHKTGTQHR-RACDLGFLELRPGQTIVIAACTRG -FW-HVADAERLFARLGKLI---- ->[subseq from] serine hydrolase n=1 Tax=Haemophilus parasuis TaxID=738 RepID=UPI00136527BE ------------------------------------------------------------- -------------KKKDLVSYSPETQKYVGKGMTIAQLCEAAVRFSDNSATNLLLKELGGV -EQYQRILRQLGDNVTHTNRLEPDLNQAKPNDIRDTSTPKQMAMNLNAYLLGNTLTESQKT -ILWNWLDNNATGNPLIRAATPTSWKV---------------------------------- ------------------------ ->[subseq from] Possible beta-lactamase family protein n=2 Tax=Synechococcus sp. WH 5701 TaxID=69042 RepID=A3YY38_9SYNE ---KLSQRWKALAAQKDLKVGGFLLVLDDGRFA-QLNPDTPLPAASSIKTPILLAALDDLD -AGKLRWNEPLPLTKEVMGGGAGWMASRPGTRFPFYEAATEMIRVSDNSATNLLIKRLGGK -AATNAHFQALGLPATVVNNWLPDLDGT------NTTSPRDLARSIALVDIGEKLSPRARD -HFRTIMATSRT-NTLLPAGLLKGLTVLNKTGDIGI-AYADAGLIELPNGKRAVAGFMVKG -PFND-PRSTDLIRAMAAAVSQ-- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645D0F9_9ZZZZ ----LNDVIKKCINDFNINCAVVVKNLNTGEEA-KVNEQMVMPAASIIKLFVMCEVFNNIN -KGKLFLEDKIIVKEEQKISYQLLTLFDEDREFTIRELLKLMICQSENTATNILIDMV-GI -DNINFFIKSLGFKNCEIQRKMLDMEAR-MQGKENYISATEVSKFLELLYNGEVINEKCSK -FMIDIMKSQLL-VAEVHRYIPDNIGLALKTGDVW-GYKHAAGIFYIDNCD-YVFTMLINY -KDDEIKFMDEFMGKMSAAVYNYf ->[subseq from] serine hydrolase n=1 Tax=Aquiflexum sp. Z0201 TaxID=2249427 RepID=UPI000DE8BE87 --qSLQQVLEKEMAGFRGDVGIYVLHLKTGEEA-AINADTIFPTASIVKVPILVGVMDKIE -KRELAYHQKMIYRDSIKYGGSGLMQYFKDSTTELSVLMSLMITYSDNTTSLWCQALAGGG -ERINEIMESLGLKHTRVNSRTPGREEDWKKYGWGQTTPREMAQLLVKIRNGEVISPSVSD -RMYRLMGNIYY-DEYALSAIPAQVQTASKQGMVN-ASRSELVMVNAPKGD-YVFYFATKN -NEEDDNEAQLLQKRISKVLWEWf ->[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. CACIAM 22H1 TaxID=1812911 RepID=A0A162NN49_9BACT --kKLEARLRQLTAEFKGEVGIYIKHLPSGKTA-AFQADTLFPTASMIKIPILLGIMQKIE -QKELAYHQPLIYRDSLLYAGEDILGSFKDGEIQLAKVIMLMMTTSDNTASLWLQSLAGTG -TEINRLLEELGFKYTRVNSRTPGRKENQQLYGWGQTTPKEMVELMERIYKGSLVSKEASD -RMLRIMGRNFW-DEEAISVHPPTIFIASKNGAVD-ASRSETLLVMAPKG-PYIFSIITKN -QQESSNEGWVLARKLADLLW--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Aminicenantes bacterium RBG_19FT_COMBO_59_29 TaxID=1797276 RepID=A0A1F5BD74_9BACT ----------------------AFRDLQTGEAL-FIKEKDMVHAASTMKVPVLIEVFKQAE -EGKFSLDDRVVIENESIVDGSSFTYGLIGTALTIRELAERMIIVSSNLATNILIELV-RP -ENVMTTLELLGVRRMRVMRGVEDSKA-FASGWNNQTDAYDLMLVLEAIASGRAGSLSSCQ -EMILILKKQKF-RNGIPAGVPGGVPVGNKTGSIT-GVEHDAAIVFPPGRRPYILVILTRG -VR--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. ALI-6-A TaxID=1933817 RepID=A0A1V2NTP2_9ACTN -----NAQLRGIFDDAGARGWLHATSLDRPDEAiALDADHVVPMASVYKLPLVIAFAELVD -RGELDPREPITLRPEDRTPGPTGLSIFSDPVMSLRDLAASTMTLSDNAAADALLEIV-GL -DRVADFLRRQGLADTRIRRGTAGNLRVYEAANASATTARDMTTLLRALWSGELLSPDQTA -FVQRLMSLQIF-TQRIASAFPDAVRVYGKTGTFG-ALRHEVGVVELPGGPTVAVAVFTRA -ARADLPRVDAAIGQATRYAVD-- ->[subseq from] serine hydrolase n=1 Tax=Chitinophagaceae bacterium PMP191F TaxID=1691979 RepID=UPI0006BBA453 --rKLQQKVEALLKDFDGQIGVYIKNLRTGKVV-MVNADTVFPTASMVKIPILIGIMDKIE -KGSLQYHQELEYKDSLLYAGSDILGSFKSGEIELGKVMMLMLTMSDNTASLWLQSLAGTG -TRINELMDSLGMQFTRVNSRTPGREENRIQFGWGQTTPREMATLFEKIYKGEVISKKAGQ -KMIRLLGRNYW-DEVAISQVPPDVFVASKNGAINQ-SRSETLLVAAPHG-HYIFSVCTKN -LSSSGNEAWTLERTLSALIWDYf ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7USP0_9BACT -------SVQALKRKHKERLGIALYDSETRVQW-SYNGDAFFHAASTMKLAVLVGVFRQVF -RKELGLETPVRVRNRSLVGGLPFSVARLGKTMNVKDLAYRMITTSSNFATNLLIDLV-TV -GVIHKALDELRVEGIEVLRGVDDQK-AFAAGKNNMVTADGLLKLLRLISDGRVYSPEISG -QLLEILLDQRV-KRGIPAGLPGGARVAHKTGHIST-VHHDAGIVYIGQRRPYAVVILTQS -PA--GAGGDAAVADASRQIYN-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000D50D346 -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG -LS-DNEQGRRLIADIGYLL---- ->[subseq from] serine hydrolase n=1 Tax=Fodinicola sp. GKU 173 TaxID=2681555 RepID=UPI0013D84C1B --------LADLLDTADFRVGVAWLSLDGTPRL-LHHQDERFYAASTMKVAVMVAVHQAVE -RGELALTDKLPLTDRYVSVADGSTESYASGSATVEHLVEQMITVSSNEATNLLIAALGGV -AKAAEAQRRLSATGSQLQRPIGDLAAN-GTGLSNLVTAYDLAAGLGRLVSGQVAGPAATE -AMTATLCRQQR-VETIAAGLPAGTRWGGKNGWVD-GIRHDSGVVWPPDAPPYALAVCTAD -FGAD-ETAIALIRTVSARVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. XS-30 TaxID=2604421 RepID=A0A5B9WHD4_9BACT --rKLEKALREIVNEFNGTAGVYVRHLKTGRYA-AVNADTIFPTASIVKVPILVGLFDKIE -KGELKYHQPLVYRDSIKYGGSGLMQFFKDSSTDISVLAALMMAYSDNTTSLWNQSLAGGG -AQINKLMEQYGLEHTRVNSRTPGREAIWKIYGWGQTTPREMSELVVKIFRGEVISPGASE -RMYRLMTKGYY-DEQAISQLPPYVQVAAKSGSVNE-SRSEVLLVNAPHGD-YVFYVGTKN -IKEPDNEAVAMIRKISALLWEHf ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. SYSU K10002 TaxID=2144174 RepID=UPI000D6939D7 ----VEDRIRAVFADAGCSGWLHARRCDSTGEI-SVDGHSRVVSASVYKLPLFVAFCRGVD -AGRVDPAARLTVLPSDCTPPTGIAVLRDPVTMSRRDLATSMMTVSDNAAADVLLGEI-GL -GAVEDLLADLGLIETRVVGGTADQYRAYDPSYTSATTPEEMTRLLRAIWTGSVLSHEQTD -FVRSVMRKQPW-SHRIASAFPRGVSVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPVVDAAIAEVARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A651GCQ9_9BACT ---DLAIEITNYLNDKEGTYAVWFEHMQKEEAYfSINPDDMFHAASTMKTPVMVELFRRAE -LGEFNLADSIKVENRSIVDGSEFQERKVGEMATLYDLNHAMITYSSNITTNLILQLV-GA -EETTQTMRKLGAENIEVIRGLYDME-AFNRGLSNRTSARDLGIMFRHIASGTAVSPEMDS -LMVEVLKDQFY-RDVIPAKLPDDVVTATKSGFIT-GVIHDSGIVYLPDGQSYILIFLSKD -LP-DAAIGREAGAEVSRMIYEHf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000852D344 ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDERFIAESVIKVPIMAAVFAASE -QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AKIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGQMATGSYLSEHACK -EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Asanoa ferruginea TaxID=53367 RepID=UPI0011C1A71E ----LTARLQAIVASAPVTAGVSVRDLSGDQQI-SVAGRFRPKAASLIKLWVLVELMRRID -CGQAAYTDGVLVLPEDVVGGTGELQHETFPQVTLFRLAQYMIKYSDNTATNVLIDYLGGF -EPVNALIDSMNQRETVLGRKMLATP-----PPENFTSPDDVISLLGAVWDRQVLRQVNRD -LMLSFMLEQTL-NGKIPAALPSGVPVAHKTGELPD-VSHDVGYYLIPGT-EIAVAFLTAG -VE---TEGAETVRQLARAVYDY- ->[subseq from] Serine hydrolase n=4 Tax=Ruminococcaceae TaxID=541000 RepID=A0A3B9WE67_9FIRM --eKLRQQIEQRLSAVTGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD -ADAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI -GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE -DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH -V--SPPEFERAMQDITLMLYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus parabrevis TaxID=54914 RepID=A0A656ZM56_BREPA ---ELEKRLSEIVQEAEGIWGVVVKELGKGICF-EHQPDELFIAESVIKVPIMAAVYAACE -QGKARIEDQLPLRKEDLVGGSGFLYALSPGLLSIRDLVTLMIIQSDNTATNMLIDFV-GK -ELIDQTMRELGMERSYYSRKVMIYPQD--VTTNNMITAGDVARMLEHIVSGSGFSRAART -EMIAIMNKQQV-LNGLPSQLPPGWELACKSGWDA-GRQHDVGILFVEGR-QFAIAALSQD -VTPE--AALHTLGLLGRAVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UJ48_9BACT ----LEKTVRGRLDALDAQSTLYAKHLATGREL-AIRADEAVNTVSVVKIPIMVLAYRDAE -AGRLSLDERHVITADEMRRGTGILQSAVGLNPTWRDLVTQMIDTSDNTATDLLIARL-GL -ERVNQMLEAMKYKETRLRMTIGQLFRGDPAKWFGRTTAREISRMLEQIQKGELAGPASTD -EMIRILKRQLY-FSRLPQRIRFRASVGHKTGDWPPIIGNDVGIIYSDAG-PIVVSVFTNQ -NRGRFFDLEAAIGKVAEDLLDAw ->[subseq from] serine hydrolase n=1 Tax=Nocardia crassostreae TaxID=53428 RepID=UPI00082E59D8 ---AIEERIRAVFADAGCTGWLHARRCDDSATEiSVGGGERVVTASVYKLPLFIAFCRAID -TGDIDPAARITVTPSECTPPTGIAAFRDPITMSRRDLATSMMTVSDNAAADVLLGEI-GL -PAIDALLTELGLTETRIVGGTADVFDAYDPSYTSATTPHEMTRFLTALWSGSVLSPAQTD -FTQIVLRAQAW-THRITSAFPRDIAVAGKTGTIGI-IRNEVAVIEFPGEIPVAVAVFTRA -ARPDLPAVDAAIAEAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=A0A2T2X1Y3_SULTH ---EAEKRIEDIVQAFSGHISFYAEHMQTHETL-TRDPDQVMETASVIKLPIMAATFQYLA -DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI -PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATVRELGMILTQLYHRTLVNKDASD -VMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH -SRHIDNEALVILPQLSRIIFDYf ->[subseq from] Uncharacterized protein n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A5C2D056_9BACT ---ALAEELRAVADGFRGTLGYSFRHLRTGDEL-EHHGDEPFPTASTIKLALLCAAMDMQQ -RGEIGYEEERVLTEETRAYGTGFAQNYRAGTVELRELLHLMITASDNSATVMLGQWL-GR -EQVNRWLDRQDLRETRLLIPFPFGGTPFRQWGMGVTTPREMRLLLEMIVENRAGTPAACD -QMLRILGRQFY-DEGIASQVPPWVKVASKNGTDAR-SRSDVAVVHAPSGD-YVLAVYTKD -AERWDNEHATAIRAVSRAVWSHy ->[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus silagei JCM 19001 TaxID=1302250 RepID=A0A1Z5IHT4_9LACO ---------KKCLKKASGQTSIYVDSLNARQPV--IMNNRSQRSASVIKLFIMVETFRQIK -AGRLTLNQEVSIPQADRVGGTGELAHQSVSQLSVSRLLTLMIRNSDNSATNVLIDRLGGL -TVINQEINRLGCTQTRLQRKMLDYQ-ALKNGKDNLTSVKDVGGLLGKLYQHRVLGNPYDA -KMLQLLRYNAN-QSKLPALINQKATIFNKTGEFDYGVQNDAAIVQKGHQ-AFVVVVLSQH -GVQSK--QIN------------- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudoxanthomonas suwonensis (strain 11-1) TaxID=743721 RepID=E6WP79_PSEUU ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALAAALGVPRAELGDSFEQVFEGYYARGLNSATLPAFGRMLERLAAGELLSPDSTA -LLLGHMRAITTGSRRIQAGLPPGADFAQKTGTQQQ-RACNVGILDPERGDGATVVVACAE -HFGELAQAEQAFQALGRAL---- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E8KVP4_9BACT ----------------QHEIGVAYLNLDSGDTF-YHSEKTVFHAASTMKTPVMFQLYRMRD -AGQLSLEDSLPVINESIVDGSPYSMRNINNKMAVRHLIEAMIATSSNLATNILIELA-DP -EAVMATLKETGADGVSVIRGVEDLKA-FDXGLSNRTDAYGLMMXMKAVFDSQLVSAKSRQ -EMIXXLKSQXF-NEMIPAGLPTGTSVAHKTGRIT-GITHDAAVVMPENDSPFVLVILTRG -WA--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridia bacterium TaxID=2044939 RepID=A0A2V2FNY4_9FIRM ---KIKQIVEKYQRGTSAPLGVAFKDLRTGATV-TCHAEEPFPTASAYKIYVLAELYRKAY -SGECNLNDRYPLTVDIKSIGSGVLEQLDAGLLTLKDYATLMMIISDNTATDFLFNFLGRD -KIKKNVIDALGFSHTKCDWGCQKLIDQCVTEENDQTAPIEALKMLELLYRGTWVNQEASE -GMLAIMKQCQT-NTRIPHFLPPGVAVAHKTGSLDK-LNVDIGIVYAQPVGDYILCMFYNG -NLASKED---------------- ->[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=A0A271JB25_9BACT -------------------------------------ADRTFHAASTMKVGVMIEAFRQVQ -AGRRAWDDPVRVENRSIVDGTEYQYALQGRDVTFRTLTERAITTSSNLATNLLIGLV-TA -ESVQATMDRLGAPGLRVLRGVEDLKA-FEAGLSNATTADALATVLEAIRDGRAVSPAADA -EMVDILDDQAF-NEMIPAGLPAGTRVAHKTGWITE-IHHDAAIVYPEGAEPYVLVILTEG -LA-DHDESARLGAEVARAVH--- ->[subseq from] Serine hydrolase n=1 Tax=Bdellovibrionales bacterium TaxID=2053517 RepID=A0A3D3GBZ2_9PROT ---KLRKSLDQLEAAHPGQLGIYVKDPESGQSL-SLRGEEAWYIASGVKLPVAITLLQKFE -NDPISLDRKLQLSREDYLDGGGATNLQPPGRLSIRYLLEQMLIYSDNTASDLLIRHI-GL -NAVNNFVQEFAPDGFSGITRLADVRRLYYAQKLNTAKLSTYGVLLEKLVESKLFARESTR -LLLEILARTATGRQRLRAGFPGHYIFAHKTGTQFK-RACDFGISWSPKPRRLVIAACVRD -FK-TTREAETALKKIGQAIYS-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus xiangfangensis TaxID=942150 RepID=A0A0R2MMD0_9LACO --sQIKQDIASTVGSIGGTNSVYVSPVTSKQSV-LVNNGT-QSSASSIKLYILVTAYAMDK -EGVLNLDHTHTVTDDEKVGGTGVIQNMDAGTLTYREILAHMIDDSDNTAANIIIDKLGGF -SLINDKIASMGATDTKLRRKMMDTD-AISEGHDNTTSARDMGVTLKKIYNHQLVSKSADD -EMLAILAKNQN-RTKLPKLLPSEATVYNKTGEFDYGVQNDAEIVKNSHGA-FVAVVLSED -GDESD------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium UBA9857 TaxID=2060923 RepID=A0A3B9QE33_9FIRM ---KMADELEEICRK-TGVMGYSVRDLKTGRKA-GFREDVLFPTASTIKIHILLGVAIRVH -RGELDWAQRVVVEDKDKVGGSGVLGHFTYKALALRDVAALMISLSDNTATNICIDLA-TM -DLVNETMRSLGLTNTLLRRKMMDIEAAKRG-DENVSTPGELATLMAKIQERDGIPEAVAE -DVLSILSLPKTGP--FTLGLPSDIKRANKPGGLGN-LSVDAGVIYPTPDRPFALAVCGSF ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI000307B9B4 ---EAEKRIEDIVQAFSGHISFYAEHMHTHETL-TRDPDHVMETASVIKLPIMAATFQYLA -DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI -PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATARELGMILTQLYHRTLVNKDASD -VMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH -SRHIDNEALVILPQLSRIIFDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter agarivorans TaxID=345907 RepID=A0A1I2JYX4_9FLAO ----LEQKLEELTASFKGDVGVYVKHLKTGKEA-AINADSIFPTASIVKVPILVKIFDKIE -EGELSYRDSLVYSEDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -EAINKLMTELGLEHTRVNSRTEGRDKDWEKYGWGQTTPREMASILEQIRKRELVSAAASD -EMYRLLGNSFY-QDYALSQVPPYIQMAAKQGMVNK-SRSELFMVNGPSGD-YVCYIATKN -NEDDDNEAWQLQREISNLLWNYf ->[subseq from] Beta-lactamase (Modular protein) n=1 Tax=Syntrophaceticus schinkii TaxID=499207 RepID=A0A0B7MNK9_9FIRM --rSLEDEIIDLTAQEQGTYGVYVIDLTTHQVC-GVNEDTVFHAASTFKLPLNIYLFQQIA -DGQIDPQTKLTYYSKHYEGGTGILQNKKYGSYTIQELAKYSIIYSDNVATNMLLGYL-GR -PNVKKMMADMGGIVV--D------NSA------NTTCPRDMALYMDALVEFNKEHPDQGA -ILLTHLKNTVF-NDRIPTLLPPDTEVAHKTGNWATGSYHDVGLVEHPSH-PYTIALFSKN -VS-SSAHAYHVLQRLSRLVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. CAG:594 TaxID=1262826 RepID=R6D3Y9_9CLOT ---------SEIEK--KEKVNILIKKVNCNETIfSYNENNVFVSASLIKVPIMLATLNEVK -NGNISLDKIITVSQDDILDDNEVFEKGK-YKYSVKELIYFMITVSDNTSTNILIKLL-GF -DYINKFIKEIGLYNTKLERYMNDWK-AIKNGKNNYTTLVDMNKCFEILINEDILNNELCN -FAINTLYGQKI-NNQIPRYIP-NVKFAHKTGGLDY-LNSDVGIFEKNG-EMYFIGISIYD -TPEKT-GDRKSTSILA------- ->[subseq from] serine hydrolase n=1 Tax=Microtetraspora niveoalba TaxID=46175 RepID=UPI0008366442 ------RQLEQIFRTAGVTGWLHAVDIDTGREV-GLGADEPVVLASVFKVPLLVAFYRQAE -RGLIDPAERVTVSPEGRAGGTGVSAMLDEVTASLRDLAYLMISVSDNASADTLLARV-GL -DEVNAALADLGLSHTWVEHSCADLFTVLDPARTSRGTCRDMTRLLGMIWRDEAAGSASCA -AVRRLMGLQVW-PHRLASGFPDDVAVSGKTGTLPT-IRNEVGVIEYPDGGRYAIAVFTRS -IGQNQPRADAVIGTAARVAVDH- ->[subseq from] serine hydrolase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI0014287267 ---EAQRRIADVFAAAGAEGNLHARALDSPAEI-GWAADEPVVLASVFKIPVALAYARQVA -AGALDPAERTTVTARDRIGGIGTAGCTDDVEMSWRDLAAFALTMSDNAATDVLLRRV-GI -DAVREVLAELGLHRTRLIGGCEDLFAVCDPARTTASTPREITALLAAIWQDTAGPAAACA -EVRAIMHRQIW-PHRLSSGFGDEVLIGAKTGTLPF-VRNEAGVLTFPDEKRYAVAIFTVA -AQANAPAIDAAIGSAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter echinorum TaxID=1073325 RepID=A0A1M5C3L1_9FLAO --aKLQQQLEQLSQDFHGDVGIYVKHLKSGKEA-SLNADIIFPTASIVKVPILIKIFDKIE -KGSLSYNDTLVYTKDRVYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -KEVNELMVDLGLTHTRVNSRTEGREKDWEKYGWGQTTPREMASLLERIRERTLISATASD -EMYRLLGNSFY-QDYALSQVPPFVQAAAKQGMVNK-SRSELFMVNAPGGD-YVCYIATKN -NRDDDNEAWQLHRDISALLWNHf ->[subseq from] serine hydrolase n=1 Tax=Pedobacter nanyangensis TaxID=1562389 RepID=UPI000DE401D1 ---KLNKMVSALMKDFNGQVGIYVKSLKTGKIA-AYNADTIFPTASMIKVPITCGIFDKIE -KGELNYNTQLTYKDSLLYAGEDILGSFKNGEIWLAKVLMLMITTSDNTASLWCQSLAGTG -LAINELMGKYGLEHTRVNSRTPDRQANQRKYGWGQTTPREMASLLSLIREGKMISKAASE -RIYRNLIRIYF-DNVALSQIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCIITKN -QQDTDNEAEVLIRKTSKMLWNYf ->[subseq from] serine hydrolase n=1 Tax=Deinococcus frigens TaxID=249403 RepID=UPI0005520777 -------------RGYRGEVGLRVCDLAGAELL-TLNPERVFPAASTIKVPLLVLALEWAQ -AGRLALEERVTLGAADRVSGAGVLHELGPGLLSWRDVLTLMIIVSDNTATNLVIGVL-GV -EAVNDWLTAHGWTDTRLVGKLEQRNAAQLRNERNRTTALEQTDMLGRLVRGELLDAAHTA -LALNILERQQF-RDLIGRGLPRAYRLASKSGELD-GVHHDVGVLYTP--RPLVIALLTSG -GTD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. HMSC76G11 TaxID=1608910 RepID=A0A1S1FR37_9BACI ---NLELKLQEVMERCPGRIGLAL-DL-DGRII-ERNSNGIFSSASLIKLPILLTAFQQKE -RGILSFDEKVKMCDIEKTGGAGVLQSFSDDALTVSDLLSLMIIVSDNAATNYMIHKA-GR -PAINACMKDLNLTSTELNRDMMDLE-AIKNGLNNWTTADDMLKCLKAIGEYGFLPEVSRK -QIEDILQKQQF-TDKLPFHMKEKVYAGNKTGELP-GIEHDCAIIRFGDRT-AYAAVLIDQ -LQ-NKEAGRRTISEIGKFIYDE- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. T22 TaxID=2203219 RepID=A0A2Z3MTH9_9BACT --rKMQQALQDIVSRFNGTAGVYVQHLKTGAWA-AIHADTIFPTASIVKVPLLVGLFNKID -KGELGYHQSLIYRDSAKYGGSGLMQFFKDSATEVSVLAALMMSYSDNTTSLWNQRLAGGG -VEVNRLMEQYGLKDTRVNSRTPGREDIWKIYGWGQTTPREMATLLIKIRRGEIISQDASE -RMYRLMCRGYY-DETALSQIPPYVQAAHKTGSVND-SRSELVMVNAPHGD-YVFYVGTKN -NKEPDNEAIEMIRTISAYLWKHf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5606 TaxID=2690305 RepID=UPI00136F790F ------ARLDAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHERAA -AGALDLTEQVECPPAGRTPGPTGLSAMLDPVMSLRDAAFWMMSVSDNTAADLLLRRV-GL -DAVNRTTERLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. es.034 TaxID=1761763 RepID=A0A2A9BW36_9BACI --nELEYKIREIMVRCNGRVSVAVELP--SHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ -EGAISLNDMVTIPKEGRVGGAGVLVSLSDQLLTVEDLVTLMIIVSDNTAANLLIERL-GS -NAIQELCHTLKLKHTRILRKLMDFE-ALEKGLDNYTSALDIITCLKVVDIGKEYSQTNTG -KMLHILQQQQF-NTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKFRDKT-AYIAVLIDE -LGES-ETGKDTIAQIGELICD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E5UI11_9BACT --tSLEETIEKQLQSLDAETSFYAKHLPTGKEI-SIRADQPMNPLSVIKIPMMILAFQDTE -NGQFDLDQRYRIRAGDMRGGSGLLQTFTTGLPTYRDLITQMIITSDNTATDIILNKL-TM -ERVNLFLEENGYLETIVKSSTGDLFRRFEGDSTGRTTAREMGMLLEQIENAELTSRKSAD -EMTNILKRQFY-SSRIPRFLRGKATVGHKTGDWPPHAGNDVAILYYDGG-PSIMAIFTNQ -NKGDFVELESTIGRIAEELVSRw ->[subseq from] Serine hydrolase n=1 Tax=Nocardia mangyaensis TaxID=2213200 RepID=A0A1J0W3A9_9NOCA ---------------------------DSGAEV-CVDGRDRVVLASVYKVLLLVAFCRRVE -DGTIDPTARLTIDPAECTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -AAMTELVDELDLTETRVLGGTADQHRAYDPSYASATTPEEMTRLLRRLWTGEVLSTASVE -FVRSVMGRQIW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Niabella yanshanensis TaxID=577386 RepID=UPI000E0C750A --kKLDVALKKEIAGFNGDIGIYVHHLKKNRMV-AINADTVFPTASIVKVPILVGVFDKIA -SGELKLSQEFIYDTSRLYGGSGLMQFYKDSATDLSTMISLMLTYSDNITSIWLQQLSGGG -MAINKMMDDLGLKNTKVNSRTEGRLEIWKKYGWGQTTPREMSKLFQLIREGKVIDARHSD -KMYRYLKNQFY-NGRSLAQFPSTVNTISKTGSVNE-ARGEVVLVNAPGGD-IVFCVLTKN -NKTDSNEAEVLTRKIAALIWNHy ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Coprobacter fastidiosus TaxID=1099853 RepID=A0A354M4K1_9BACT --rELKMRIASVLKEKRAIVGVAVLY-GDNRLF-EVNRG-DYPMMSVCKFPLALAVLDYLH -KNNLSLDTDIFIRESDLLPYSPLRDRHPQGNMSIRELLSYTVSLSDNNACDILFGYIGGT -KVVDDYIKRLGISGMSVVATEAVMHESFEKQYCNTATPSSAVLLLDKFLKEDLLRDEYGN -YLRKIMIETSTGNDKIKAGLPEG------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A5B8Q583_BACME -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG -LS-DNEQGRRLIADIGYLL---- ->[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A353CAZ0_9BACT --qSIDARVQAAIGDFKGKVWIYAKNLDTGKDY-GLRSDEQVRTASTIKLPIMTEVFRQVA -EGKIAWTDEIVISKQNKVGGSGILGEFTDGSIDLRTATNLMIVLSDNTATNIVLDKV-TS -NAVNDHMAKLGLKDTLSLRKVGGGGDAKAYDEPGRSSPKDMVRLLEMLERGEVVSKEASA -EMIAILRRQQY-KDGIGRNALDTVPVASKSGSLDR-LRSDVGIVYTRRG-RIAMAITVDD -M---------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=A0A1J6WVK7_9BACI ----LEEQIHELIEGVEGRISLYIEL--PAHTL-KMNSDVPYSAASLIKLPILLEGFRQIQ -EKKLELDEVIPVTPEDKVGGAGVLSHLSPHTVTVHDLLTLMIIVSDNTASNLLINRM-GM -DSVNGMCRLLGLEQTKLNRRLMDFE-ALEMEVDNHISATDAVKCLKAMENDDLFQLNSRE -SMLRILQNQQF-YQKLPGSMDRNVVTANKTGELP-GVEHDCAIIRYKHQ-TIYAAVLIDE -LK-DSSEGSGLIMKVGKCLND-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus aryabhattai B8W22 TaxID=1358420 RepID=A0A1G6PMJ4_9BACI ------------TKWKQSNNGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID -EGILTLTSVIQRTEKNTVGGAGVLGALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECARNMGLKKTVLNRYMMD-ETAVKQGLDNYTCASDVVECLREIYEGNLLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LSEN-EQGRRLIADIGYL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides xylanolyticus TaxID=384636 RepID=A0A2S6HMV7_9BACE -----RDEIIRILDQVPGKISFLYENLETGERV-GYREDQPLMAASVIKLYVMAAAFNQFE -TGKLRQDFSLPIYKKDCVPCGALTYLHEGICVTALDLVTLMIIFSDNTATNLLIELL-GM -EEINQYIKSLGFEKTCLNRKMYDTEKS-SKGIQNYITASETGRLLMMMYRGELVSEGASR -QMISILKNQQL-CSKIPFYLQEEPEIAHKTGEDR-GITHDVGIVYGK--TPFLVCF-CGN -ET-DTPGFERIMGELS------- ->[subseq from] Beta-lactamase class A n=1 Tax=Niabella drilacis TaxID=1285928 RepID=A0A1G6WUT6_9BACT --kKLKVLIEKAVSDFHGDIGVYVHHLKKNKSV-ALNADTVFPTASIVKVPILAGVFNKIA -KSELKLSQEFVYDAKREYGGSGLMQFYKDSATDLSTMISLMLTYSDNVASIWLQELAGGG -VAINTIMDQLGLTNTKVNSRTTGRQDIWKKYGWGQTTPKEMAQLFTLIRQGKVVNARYSD -KMYRYLKNQFY-NGRSLSQIPATVNTICKTGSVDD-ARGEVVLVNAPGGD-IVFCILTKN -NKTDDNEAEILTRKLAHIIWNYy ->[subseq from] Serine hydrolase n=1 Tax=[Brevibacterium] frigoritolerans TaxID=450367 RepID=A0A4R6AC18_9BACI ----LKLKLQEVIDRCPGKIGLAIVL--DGEII-EWNSNGIFSSASLIKLPILLTAFRLKD -RGILALNEKVNLRDIEKTGGAGVLQSFSDDALTVSDLLSLMIIVSDNAATNYMIYKA-SR -PAIHACMKDLNLTSTELNRDMMDLE-AIKNGLNNWTTADDMLKCLKAIGEDGFLTEVSRK -QIEDILQKQQF-TDKLPYHMDDKVYAGNKTGELP-GIEHDCAIIRFGDRT-AYAAVLIDQ -LQ-NKEAGRRTISEIGKLIYDE- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A5C8DKR3_9BACT --kKLEAELRKAITGFNGAIGIYVKNIKTGETV-AINADTVFPTASIVKVPIMMGVMDKMQ -KGELHYDSTHIYKDSLLYEGEDILGSFKDGEIALKKIIMLMLTTSDNTASLWLQKLAGTG -TRINALMDSLGYINTRVNSRTPGREEIRKIYGWGQTSPAEMGRLFEQIYQNKLFTPAACE -RIMRCLGRNFWDEDEAISMIPPYIEVFSKNGCVD-ASRNEALLVNAPNR-PYIFCIFTKN -NKTHANEAWTLTRKISSLLWDYf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A429A4Y6_9ACTN ------ARIHAAFADAGVTGRLHAVGIDSGVQL-DAGADRPVPTASVHKLCLLVALHAQDA -AGRLDLTEQVECLPADRTAPTGVAAMLDTARLSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHSFGEMLAALDPARTNRSTPRDLTRLLAAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Flexithrix dorotheae TaxID=70993 RepID=UPI000475640C --qKLANEIKKTFAEVKGDFALAYISLDNPSDSlLINAYEEFHAASTMKTPVMIEVYKQAN -EGKLNLDDSIMIYTRSIVDTSTFIEKLFEKEWPLRDVMYKMIIESSNLGTNLLVEMV-DA -KNITQTMRELGAPKINVLRGVEDIK-AYRKGLSNSTTAYDLMKIFEGLGNGTVVNKDASE -EMIDILLDQKY-NEIIPAKLPQDVKVAHKTGWIT-GVHHDSALLMLPNGKKYVLVLLSKN -LE-DEAKGVEALATASKLLFDY- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AU30_9CHLR -----------ALATLPGEAAAFASDADGHALF-CEREDELFPSASVIKLPLVMTLYADAT -RGLIDLDERVAVG--DRVDGSGVLRHMRDVELSLRDLAMLAIIVSDNTATNRLIERI-GV -DRVGERLREWGCPKTRLSRKMYDFEAA-KRGHENVMTARETVSLLVRLQRGECEDRATSD -AVLAVLEQCQD-RTMLLRYLPYGAKVPHKTGTLDE-SRNDAAIV--PGERPVIVAGFTRK -LRDT------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Salegentibacter holothuriorum TaxID=241145 RepID=A0A1T5D4L3_9FLAO ---ELQQKLEALIDDFKGEVGIYVKNLETGKEV-AINADTIFPTASIVKVPILVKIFDKIE -KGDLNYNDTLVYSSDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -ESINKLMAELGLEHTRVNSRTDGREKNWEKYGWGQTTPREMASILVEIRNRELISPAASD -EMYRLLGNSFY-QDYALSQVPPYVQAAAKQGMVNR-SRSELFMVNAASGD-YVCYIATKN -NKEDDNEAWELQREISALLWKYf ->[subseq from] Serine hydrolase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=A0A1B2I047_9PSEU ----VADRIREAFAEAGTEGFVHAREVQDGPEV-GVGADDPVVLASVFKIPVAVAFAAEVA -AGRLDDTQRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ -AAVDAVLANLGLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLDAIWTGRAAAPQACE -RVRSIMAQQVW-PHRLSSGFPADVQVAAKTGTLP-GVRNEAGVVTYPDGRGYAVAVFTRA -ESLRQPAVDAVIGRAGRLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A11294B -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. WAC 01424 TaxID=2203200 RepID=A0A429AGQ7_9ACTN -----ERDAQKVFAAAGVRGFVHARDVDGEAET-GLDPDAPVVLASVFKLPILLEYARQAA -AGEVDRTERLTVTEADKDGGIGTSGCADDVSLTLRDLAHFMMSMSDNAATDVLLRRV-GL -DRVNATLEHLGLRRTRLIGGCATLFEVRDPQRTTAGTPREITTLLGLVWRDEAGPAEACA -EVRDIMSRQIW-PHRLSSGFPDEVRVSAKTGTLW-GVRNEAGVVEYPDGGRYAVAVFLHG -DNFRMPAADAAIGEAARLAVEH- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI00119FA2F7 -----------------------------GVDI-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A10CB05 -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRI-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus marmoris TaxID=249408 RepID=UPI000496ADCA -------------QGYVGEVGLRVCDVLGRELF-ALNPERVFPAASTIKVPLLILALEWAQ -AGRLDLEGRVTLQAADRVPGAGVLHELGSGLLSWRDVLTLMIVVSDNTATNLVIEQL-GM -DAVNGWLNAHGWTDTRLVGKLEQRNAAQLRGERNRTTAREQTDILGRLVRGDLLDAAHTA -LALDILERQQY-RDLIGRGLPRAYRLASKSGELG-GVHHDVGVLYTP--RPLVIALLSEG -GM--------------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Arcticibacter pallidicorallinus TaxID=1259464 RepID=A0A2T0U4G0_9SPHI --hKLEKALSRLVDTFKGSVGIYVMNLRTGKYA-SLNGDSIFPTASIVKVPILVGLFDQIE -QGKLSYHQPMIYRDSIKYGGSGIMQHFKDSSTEVSVLAHLMMSYSDNTTSLWNQQLAGGG -EQINKLMDKYGFPNIRVNSRTKGREEIWKKYGWGQSTPREMASLLVKIRNGEIVSKAASD -RMYRLMTKGYY-DEDALAQIPPYVQAAAKSGAVD-ASRSEVVLVNAPSGE-YVFYVGTKD -NADQDNEGQVLIRKVSACLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RNZ9_9CHLR -------ALERHLDALRGRAGVFICEADETARF-SRDADEIFPAASVIKVPLVMALYADAA -RGAVDLEQCVGVGE--RVAGTGVLARLRDVHLTLRDYAMLTIMVSDNMATNRIIDRV-GI -EVVNAYLDRWGCPRTRLRRKMFDLDAR-AKGLDNVMTPRESAHLLAMLVRGELVDRATSD -AVLELLAATMY-DGKARRYLSGDVSTANKTGRLD-GVRNDIAIIRVS--RPVILAAFTRD -LARES------------------ ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI00119F663C -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A102822 -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Verrucomicrobia bacterium SCGC AAA168-F10 TaxID=1009423 RepID=UPI00056E8994 ----LASKLETRVAELDGEVGLYVYHLETNHSV-LINADELFPAASMIKVPILASLLNKVE -RGELGYQDKLTYTKDRLYPGEDLLGSFANNELTLKKLVFLMITTSDNTASLWCQELAGTG -TTINTWLKKKGFLRTRLNSRTPGRVTAQDRYGWGQTTPREMAQLLIRIRNRKLVSAAADE -EMARVMGRIYWDGEAI-SSVPPSIATISKQGAVN-ASRSEVVLVHAPHGD-YVFCVITKN -QKKHDNQGFSLLRDISRILWEHf ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga rupis TaxID=573321 RepID=A0A1H8DJF8_9BACT --kQLTALLRPYLEKHHGVAGIYVHHLKKDKYV-AINADTLFPTASTIKMTIMVGIFDKIA -KGELQYHQPLVYKDSLLYAGEDILGSFKSGEITLDKVMMLMLTMSDNTASLWLQSLAGGG -QQINAWLEAHGFVNTRVNSRTPGREANRTALGWGQTSPREMARLMEMIYKGEVVSKAASE -RMYRNLTRNYW-DQEGLLEFPKEVRTASKNGAVD-GSRSEVVMVSAAHGD-FVYSIYTKN -NLERNNEAWQLLRQVARTIWNYy ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. KSM4-11 TaxID=2568654 RepID=A0A4S4CF89_9DEIO -------------RGFTGSVGLSVTTLDGTVRV-ALNADQVFPAASTIKVPLLLLALERAQ -AGQLDLTARVVMDASDRVTGAGVLHDLSGGLLTWQDVLTLMIIVSDNTATNLVIGQL-EV -NAVNAWLDAHGCGATRLVGKLEQRNEAQQRGERNRTTAREQTELLGRLVRGELLDAAHTA -LALDILSRQQH-RDVIGRRVPPRYRLCSKSGELE-GVHHDVGVLYTP--APLVVALLSEG -GT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Lysinibacillus sp. SDF0063 TaxID=2133753 RepID=A0A544UPP2_9BACI ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEDLVGGSGLLYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -DQIDQTMIDLGMHQSCYSRKLMIYPLD--ITENNKITAGDVANMLGHLATGSFLSQRACK -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) TaxID=485917 RepID=C6Y376_PEDHD --hKLEKELNTLISGFKGTVGIYTMNLKTGKQA-GIYTDSIFPTASIVKVPILIGLFDKIE -KGELSYHQPLMYRDSIKYGGSGIMQFFKDSSTELSVLANLMMTYSDNTTSLWNQRLAGGG -ARINEVLEQYGFKDTRVNSRTKGREAIWKIYGWGQTTPREMATLLVKIRKGEIISKAASE -RMYRLMTKGYY-DENALAQIPPYVQAAAKSGAVNE-SRSEVVLVNAPHGD-YVFYVGTKN -IKTPDNEAEQLIRKVSALLWKYy ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0007CD6BCC -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] Putative beta-lactamase n=1 Tax=Rhodococcus hoagii (strain 103S) TaxID=685727 RepID=A0A3S5YBS1_RHOH1 -----------------------------GVDI-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Frankia sp. Iso899 TaxID=1283283 RepID=UPI0009DBAED2 ------SNIKEEASKIGARVFAHAIDIDTGVDA-GIDAEHPVVTASVFKVPVLAEYVRQVS -IGDLDPRTRIVVKAADATPGPTGLSVFNDDAWSLRDIATSMITVSDNTATDIVCRLV-GI -DRVNALMESLGLSGTKLVGDCVDTFAICTPSATNRTTPRDATRLLELLWTDKVASPDACA -QARAILGKQVW-THRLSSGFPDDIRVSGKTGTIGI-VRNEIGVVEYPDGRRYAVAIFVRT -GEYRNPAADRLIGTAARLLVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. FJAT-29937 TaxID=1720553 RepID=UPI00082CEA8E --dNLKRQVSELVAHCEGRVGLVIETCEGR--I-EINHNDKFSAASLIKIPILIEGFRQCE -KGLLDLHEYLLALPSNRVGGAGVIQALSADLLKIIDLMALMIIVSDNSATNLVIDRV-GM -TEINECIKALNLQNTELNRKMMDFEAK-KNGLDNFTTANDMLTCLKVIDQHRFLSKESSD -KAFSILEKQQFKNKLAETIDSEAVQVANKTGELP-GVEHDCAIFKYGGK-TIYAAVLIDQ -LS-SQEEGKQTLVQIGKVL---- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0009C00809 -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTAPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Marinamargulisbacteria bacterium SCGC AG-439-L15 TaxID=2184346 RepID=A0A328RGS4_9BACT --qQLRQTLQQYSDTQNTTVSLVYMSTNSSESV-ALNPRLSVNPASVIKVPILIEAYRQLE -MGRLKKGQLFEMKKEHLQKGAGRLKYHALGTYTIHDLLYHMIVNSDNTATKMLIAIL-GQ -SRINEGIKRLGLRDTYLHTDN--L---LTGQPKNKASAYDMALLLHKLYRGEVISKGASD -EIVRLLSKQKY-RWGIPQQLPKKLRVANKTGSLRW-VSHDVGIVFFPDA-PYILSIFVSD -IKTT-LQARKQVAKLSQIVYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Parabacteroides johnsonii DSM 18315 TaxID=537006 RepID=B7BEE4_9BACT --kAIENALQEYIKGKDARIGIAII-INGKDTV-SVNGNRDFPMMSVVKFPLALTVANWVD -TNNMSLSDTVTFSGKSLKEYSPMLKKYGKSRMTVRELLEWSLVESDNNAADILLNCVGGV -SGATSKMRQIGIDEIVIGASEEDMHRDPYLSYLNRTTPLAMAQLFDRFNNEMRNASQSYS -EISVMLKQCRTGLDRLALLLPTNATIGHKTGTGF-------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Fibrella sp. ES10-3-2-2 TaxID=1834519 RepID=A0A1W6E180_9BACT --tKLTQKLTEALRGFRGDVGVYVHHLKTGKTV-AINADTTFPTASTIKIPIMIGLFDQIE -KGKIGYQQEVVYRDSLHYDDGIVGSLKDGAKLSLSEVVMLMETVSDNTGSLWCQKLAGGG -IAINAWLDTNGFPQTRMNSRTPGREAYQKRYGWGQTTPRELADLLTYLRQGRAISPDASD -RMYRNLCRQFW-DNDGLSQLPVEVKVACKTGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKN -QKDETNEGFTLLRTVSALIWQHf ->[subseq from] serine hydrolase n=1 Tax=Nocardia mangyaensis TaxID=2213200 RepID=UPI000A01A774 ---------------------------DSGAEV-CVDGRDRVVLASVYKVLLLVAFCRRVE -DGTIDPTARLTIDPAECTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -AAMTELVDELDLTETRVLGGTADQHRAYDPSYASATTPEEMTRLLRRLWTGEVLSTASVE -FVRSVMGRQIW-PHRIAAAFPRGVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Serine hydrolase n=2 Tax=Ruminococcaceae TaxID=541000 RepID=A0A0W7TVI8_9FIRM --eKLRQQIEQRLSAVMGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD -ADAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI -GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE -DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH -V--SPPEFERAMQDITLMLYE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Vibrionimonas magnilacihabitans TaxID=669455 RepID=A0A2S8SGI9_9BACT --qRLQQQVTQLLKGFNGDIGIYVHDLKRDRIV-SINADTVFPTASMVKVPILTGIMDKIH -RKELDYHQVLTYKDSLLYEGVDILGSFKNGEIELSKVMMLMLTMSDNTASLWLQTLAGKG -TRINELMDSLGLKVTRVNSRTPGREANRNMYGWGQSSPREMASLMEMIVKKQVIGDSTSQ -MMLRLLGRNYW-DENAISQIPSDVFVASKSGAVD-ATRNEVLFVNGKKC-SYVFCICTKN -NKESTNEAWVLTRKLSKLLWEYy ->[subseq from] Beta-lactamase n=2 Tax=Chroococcidiopsis thermalis TaxID=54299 RepID=K9U3H5_CHRTP -------DFQPLVANFQGTTGIIIKTLDSGSCF-QFNPNLVFPAASLIELPILWEFFHQCA -TGSLDLAEEIELQSEDMVIGFGILRQLKPGLLCLYDLAVLMTVVSDNTATNLLIDKL-GI -DNINDSIQRIGLTHTILQYKMYDSIS---TSQDNLTTPSDMLRMLEAFIQDKHLLSKYGD -EPLKILEGQQC-KNKLHLGIPKGARLANKTGETL-GTEHDIGVLLGREE-TVIIVVMTTG -LSEN-YQGIELCRDVARLVYQ-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus sp. Leaf406 TaxID=1736368 RepID=A0A0Q6L9X1_9BACI --kDLREDLMKIVHECPGSVSFTILS--NDESL-SWEENRRISSASLIKLPIMMAAFEQIQ -TGSLKGDAMVVLRHEDHVEGAGVLYGHDGITLSIEDLLTLMITVSDNTATNQLIELI-GK -DSINRFCLSWKLKRTFLNRKMMDFRL-LEMGQDNWTSSMDVVSCLRGINEGPF-EEASRR -KMLMMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDE -LQVP-EDGRMAISRIGKLVYDY- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A318ASS1_9CAUL ---TLNPRLAALAERAPGILGVAAQDLTTAQRI-ATAGDRPFPMDGVWKAALGAAVLSEIE -AKALSPSEILTIEDVDLSPPGAVADAWPAHGYTVEDLFKRAVALSDNTAADVLLKRIGGP -GAVTAWLELRKVEGVRLDRYARQLLPRYLADPRDTATPLGAVRFLEALNQFELTSQDGRG -RLLRLMEAAA--GDRLRPALPAGARLAALTTWTPYDADATLAMVQMQDGRRFALAIFLKA -SPLEDEDRTALIVDIARTVL--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces canus TaxID=58343 RepID=UPI0007501FB8 ---AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHERAA -AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGETLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. E5N298 TaxID=1851983 RepID=UPI000EF59F95 ---AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHERAA -AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGETLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. M1013 TaxID=549798 RepID=A0A1R1WM30_9ACTN ---AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHERAA -AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGETLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQAVLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter jiangsuensis TaxID=1591085 RepID=A0A2P8G408_9BACT --kKLTAQLEAALAGFHGQVGVYVRNLKTNRIA-AVNADSLYPTASMVKVPIMCGIFDKIE -KGEITFNQELVYRDSLKYDNGIVGSFRDSTKIALPKVVHLMISQSDNTGSLWLQAMAGGG -TAINQWLDGNGFANTRVNSRTPGRKEFQARYGWGVTTPREMAELVAMIRNGKAVSPAASD -RMYRYLGMQFW-DDEAISQLPSNVKIAAKSGAVNQ-AKSEVLVVHAPHGD-YVFCIATKN -QEQKDNEGYALIRKVSAIIWKHf ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus nasuensis JCM 17158 TaxID=1291734 RepID=A0A0R1JGN7_9LACO ----VTTPLTQAVAGLAGTTSLYLGDPATGQTWtYHNGPQR--SASTIKLFVLGAAFAQAK -AGRFALNATYVLQASDKVGGTGTIQGLPAGTLTRQALLTKMIQVSDNTATNIIITQLGGF -GVVNAFARSIGATHTVLARKMLDTA-ALARGVDNRTTVADTGLLLTKLANHRLVSASADS -AMLTMLAGQTN-RSKLAAGAGSGITVYNKTGEYDYGVENDAAIFRRGQRQ-RVIVMMSQG -GTLS--AQIPAFNAVGRLV---- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0003B1E9A4 -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGISQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. AK5 TaxID=2587159 RepID=UPI001153496F ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEACPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus pimensis TaxID=309888 RepID=UPI0004B197E3 ---------------HPGRVGVTVHDLATGELLfAHDADHVYHAASTIKVPLLIRALQRVA -AGDLRLTDRHVMLAGDQVGGAGVLHELSPGLLTLRDLLTLMIVVSDNTATNMVIDRV-GL -DDVNAFLAEAGLRDSALVGGLQLPPERQRAGERNRTTARDMGRVLLGLARGAYLPDDLNE -LALGILSRQQY-RDVIGRGLPTDYRVASKSGELL-GVHHDVGLVWTP--RPLAVAVLSEG -GL--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NCT0_9BACT --kKLEGMLKAVADSFHGVAGIYVHNLKTNREV-AINADTIFPTASIIKVPILVGMFDQIQ -QGTYKYHTPLVYRDSMSRKGSGLMQFFKDSTTDVRTAITLMITHSDNAAAVWCERMAGGG -STINTWLDAHGFKDTRLNARTPGRETARQQYGWGQTTPREMAKLAAMIRNEQAVSPEASQ -TMYRIMTHSFW-DEYALFSLPPYVQAASKQGMVDD-SRSEIVVVNAPHGD-YVFYVATKN -NKVEDNEAWQLARKVSAMLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7Q974_9BACT ---SLSDKLSLLIKAHQGKVAIGLKNLTTGETY-YHQGDLVMPTASLIKLGVMATAYRLSD -QSKIGLNDMVLLQKEDKVPGSGILTSNFTEGFPLKDAIRLMIAYSDNTATNLVLDHI-GI -RTVNTTLAQMGLPNTRINAKVFKGSTQTKKYGLGSTTAKETIDLLELIYINKAATETSCK -AMIEHLKKCEN-KDMIPRELTKLKSLAHKIGAVSD-ARTDAGILYFDGG-PVVLCVLTTE -NMTSENSAEILIGKIGLSVFEHf ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus sp. NRRL NRS-603 TaxID=2126351 RepID=A0A2P7WHS2_9BACL ---ELENRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVNLMIIQSDNTATNMLIDLV-GK -AQIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGHLAKGSYLSQRACQ -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKN -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga niabensis TaxID=536979 RepID=A0A1N6J2L7_9BACT --hKLEKALAELTQGFNGTAGVYVLNLKTGKYA-SLNGDTIFPTASIVKVPLLVGLFSKIE -KGELGWHQALVYRDSAKYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLWNQQLAGGG -EEVNKLMEQYGLKDTRVNSRTKGREEIRKIYGWGQTTPREMSALVAKIHRGEVISKAASE -RMYRLMTKGYY-DEQAISEVPPYIQVAAKSGSVNE-SRSEVVLVNAPHGD-YVFYVGTKN -IKEADNEAVVMIRKISAYLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. p52 TaxID=935199 RepID=A0A1B2UCV7_9NOCA -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans SB3094 TaxID=1435356 RepID=V9XLG3_9NOCA -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI0013B97E07 ---ATAARLDAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRNEAAPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI00046345D7 ---EIKKDIGATVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK -EGVFNLNDTHTLTNDEKVGGTGVIQNRVGTELSYREIIEYMIDDSDNTGANIMIDKLGGF -QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD -EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED -GEET--DQLAAMNKLGLM----- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599) TaxID=358681 RepID=C0ZJI1_BREBN ---ELEKRLSAIIGQAEGTWGVVVEEQGSAKRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -DQIDQTMIDLGMHQSCYSRKLMIYPLD--ITENNKITAGDVASMLGHLATGSFLSQRACK -EMIAIMKKQQV-RNGLPSQLPHGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. 94 TaxID=2183922 RepID=A0A495SZU6_9SPHI --qKLTAQLQAATKGFNGDIGIYVQNLKTGKTA-QINADTLFPTASMIKVSILSGLMDKIQ -KSELQYNQKLVYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-GA -ENINNWLDANGFKAMRVNSRIPARRPIWEKYGWGVTTPREMCRLFTMIRDGKAVSPAASE -RMSRTLNRIFW-DETALSQIPPYVQTMSKQGAVD-ASRSETVLVNAPHGD-YVFAVITKN -NKTKDNEADVLIKKVSALVWHYy ->[subseq from] Beta-lactamase class A n=2 Tax=Lactobacillus senmaizukei TaxID=431273 RepID=A0A0R2DEA2_9LACO ----------QTVGKLKGHNSVAIATSFSGDHY-QWHNQ-AQRAASDIKVFILATVYHQVD -QGKYQLSGHYTLRDADKVGGTGSLQGMAAGTVTNQQLLHYMMTVSDNTATNVILRQVGGL -GVVNQYARELGAKDTHVVRKMMDQK-ALDAGTDNLTSVADLSMVLMKLWRHQLISTSADT -AMLKLMSENTN-HSKLPKNVPTDRTIYNKTGEFDYGVENDAAIFAK-GGKAVVVVAMSEG -GQQQIPAMNRL------------ ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus pyridinivorans AK37 TaxID=1114960 RepID=H0JPM0_9NOCA -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Compostimonas suwonensis TaxID=1048394 RepID=A0A2M9BU93_9MICO -----TAQLDALVAEAGVRMGVSVTDLSGDASV-TVGSEEQYKAASLIKLPLLGLLMDDAD -HGTLSLDESITIPADNIVGGSGTLRDRAFPLITVRELMELMVQISDNTATNVLIDRAGGF -DAVNEYIAALGYEQMWLGRKMI--HPALPPLQENWLNSEEVTDLLTKFYKHEILSPASSE -HIIDLMKGQLV-DTKFGAVIPRE-VLANKTGELGD-VTHDSGIILVPGREVALAATTAFD -PSRPRTEVDLYVQRAATIVYE-- ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salinarum TaxID=447422 RepID=A0A2N0TU74_9FLAO --tKLEQKLKELTESFKGDVGVYVKHLKTGKEA-TINADTIFPTASIVKVPILLKIFDKIE -NGELSYKDSLVYSEDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -KAINELMAEIGLEHTRVNSRTVGRDKDWEKYGWGQTTPREMASILEKIRNRELVSAAASG -EMYRLLGNSFY-QDYALSQVPPYVQAAAKQGMVNK-SRSELFMVNAPSGD-YVCYIATKN -NEDDNNEAWQLQKEISALLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus antibioticus TaxID=2570228 RepID=A0A4U2Y0Y2_9BACL ---ELEKRLSAIIGQAEGTWGVVVEEQGKGIRF-EHVPDELFIAESVIKVPIMAAVFAARE -QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNVLIDLV-GK -AQIDQTMCDLGMRQSYYSRKLMIYPLD--ITENNKITARDVANMLGQMATGSYLSERACK -EMLAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTKNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Hungateiclostridium thermocellum (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) TaxID=203119 RepID=A3DEM2_HUNT2 --aALENKLRKYISKYNCYFGIYFVDLESGKEF-GINDTEEFFAASTFKIPLNLYVYDMIR -KGMLDPMTSLEYTEEDFEGGTGIIWNSFGKTFTIKELLRLSIVYSDNVAVNMLLRCV-GK -ANVKEYMRRLGGVVV--------------DDGKNVSCPRDMAMYLKEVYELSENGDPWGR -ELVQNMINTKF-YDRLPVLLPKNLKIAHKTGNYT-GVVHDVGIVYAE--KPYIVVVMTKN -VK-NGQSANKAIANISKMIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Planomonospora sphaerica TaxID=161355 RepID=A0A171BK04_9ACTN --------------------FLHAVDLDTGAEI-AHGADQAVVTASVFKVALLVEFFRQAD -RGALDPAERVRIVADGHTPPTGVSAMTDDVTISLRDLAYLMIAVSDNTAADTLIGRV-GL -AAVNTMLASFGLAGTWLEHDCAGLFAVLDPARTNRSTPRETTRLLGMIWRDEAASPESCA -WMRRLLGLQVW-PHRLASGFPDDVAVSGKTGTLPT-LRNEAGVVEYPDGGRYAVAVFTRS -TAQNQPRADAVIGTAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus horneckiae TaxID=549687 RepID=A0A2N0ZJM9_9BACI --kQLESEIKELAANLDGRASIYIESA--AGVI-DVDGHHSFSSASLIKVPILMAAFHQCE -QNQLKMEEKLLVSTDRKVGGAGVLQALSNKLMKLIDLLTLMIIVSDNTATNILIERL-GM -ENINKYIHSLGMRNTLLQRKMMDTV-ALENGIDNKTTAADMVYALKSIKAKQLFSAENSN -KMLEILSQQQF--LKLADGIDEYFTVASKTGELA-GVQHDCAIISSQQT-VLYAAVLIDE -LTLP-ETGKKTLL---------- ->[subseq from] Serine hydrolase n=2 Tax=Chroococcidiopsis TaxID=54298 RepID=A0A433UQ26_9CYAN -------DFQPLVSNFQGTTGIIIKTLDSGSCF-QFNPNLVFPAASLIELPILWEFFHQCA -TGSLDLAEEIELQSEDMVIGFGILRQLKPGLLCLYDLAVLMTVVSDNTATNLLIDKL-GI -DNINDSIQRIGLTHTILQYKMYDSIS---TSQDNLTTPSDMLRMLEAFIQDKHLLSKYGD -EPLKILEGQQC-KNKLHLGIPKGARLANKTGETL-GTEHDIGVLLGREE-TVIIVVMTTG -LSEN-YQGIELCRDVARLVYQ-- ->[subseq from] Beta-lactamase n=1 Tax=Stigmatella aurantiaca (strain DW4/3-1) TaxID=378806 RepID=Q08XP3_STIAD -----NRLVEEAVRGFDGELSLYVLDVTSGEEY-AYDAERPTYLSSAIKLGVMLEVMHQVD -QRQLSWEETLTFTPEAIRDMHRLHRAQPGDTLSVSTLLEAMMVDSDNAAADLLIQRV-GV -DNVQAQLAARGVRTGPVSSLLEERRRAFYADNVNSASMRDMGHLLQQVARCEGLSAASCT -RAHALMRACQTGSARVAAGLPEAAAWAHKTGTQHR-RACDLGFLSLPSGHTAVIAACTRN -FW-HVSDAERLFAFLGESL---- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. FeSDHB5-19 TaxID=2528713 RepID=UPI0010754CC2 -------------RGFAGEVGLLVASLDGEVLY-RHAEDRGFPAASTIKVPLLIAALQRAQ -AGDLDLDGRVMMQDTDRVPGAGVLHELAGGLLTWRDVLTLMIVVSDNTATNLIIERL-GL -DPFNAWLRARGLRETRLVGKLHLRTEAQQRGERNVTSARDQAALLLGLVRGEVLDGEHTL -LALEILKRQQL-RDIIGRRVPRDYAVASKSGELS-GVHHDVGVLYTP--RPLVVALLSQG -GHDPRE----------------- ->[subseq from] Serine hydrolase n=1 Tax=Halomonas sp. PYC7W TaxID=2282305 RepID=A0A368TRQ0_9GAMM ------------------------------------------------------------- ------------------------------------------------------------- ------LARRLGDARDALQTSLDDAFRAYYGTDLNAGRLDTFAELLAALGEGRALGDEATA -ELMAILSRTSSGKRRLKAGLGRDIRFAHKTGTQHR-RACDAGIATHGEGRQRVVVVACAR -GVLNVARSEQILAAVGRALYE-- ->[subseq from] Putative beta-lactamase n=1 Tax=Gemmatirosa kalamazoonesis TaxID=861299 RepID=W0RMR3_9BACT ---RLHRTLDSLAESHRGILGYTVWNLDTGERL-ERRGDETFPTASLIKVSILVTVFDLVE -KKMLSLDDPLTVLKIDQVPGSGTLQFHPGIEISVRDAAWLMTTISDNTATNLLLDRI-VI -RRTWDKMESLGLMHTKVHSKSFIRAASVAMDSSGVTTPNEMAKLFALLADGKAVSPAADS -TMLDFLAHNQDET-KLVRWV-DGVRVAHKTGDVDQ-SRADCALFYLQSR--VVVCGLTKE -NVAIDAEGNAVLARLGKAVADAw ->[subseq from] Serine hydrolase n=1 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TQS0_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALARALGVERSELRTSLKAAFDDYYDSGTNAATLPAFARMLERVAAGELLSPESND -ILLSHMRAITTGGRRISAGLPAGTDFAQKTGTQLE-RACNVGILDAGKGEGATVVVACAE -DFGELAQAEQAFQSLGQAL---- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus fortis TaxID=2126352 RepID=A0A2P7ULI3_9BACL ---ELEKRLSAIIRQAEGIWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -HGQFRLDDQLALRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AQVDQTMIDLGMKRSYYSRKLMIYPLD--ITENNRITAGDVASMLGKMATGSYLSQRACK -EMIGIMKKQQV-RNGLPSQLPSQWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VTA--QSALNTLGLLGRAVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=A0A2N3Y447_SACSN -------------DGLPGRAGFAAWDLDEQEPV-LVDAEQVVHAASTIKVLIMIAALRAVQ -EGRIGLDEYVELPAE-RVGGFGILRELLSVTISLRDVITLMIVISDNAATNAVIDAV-GF -EAIRDCAADLGCTATRVERRLMDPNAH----GRNETTALDQARVLDALARGAALPPDLTE -HALEVLSKQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGAD-RPQAVVAVLVDE -LTDER------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces ochraceiscleroticus TaxID=47761 RepID=UPI0004C77F65 -----ERTIREMFADAGVRGWLHVAELDRSARV-TLDPDEAVPMGSVYKVPLMVAFCRLAD -AGELDPRARLTLEPPDRVAPTGISILRDAVTMSLRDLVVMMMSVSDNTAADALLRTI-GT -SVVDEVCRDLGMPDTRIHGGVAGTWDVYNPLSKAATTPADMARLLRAIWTGRAASPERCA -FMREVMGRQPW-RHRLASGFPDDVTVSGKTGTFG-AMRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=UPI00110D9FF1 -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDWTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TTVEKLLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Lentzea guizhouensis TaxID=1586287 RepID=UPI0009F23DF5 ---------------TEGFVHAREIGVQDGPEV-GVGADDPVVLASVFKIPVAVAFAAEVA -AGRLDDTQRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ -AAVDAVLANLGLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLDAIWTGRAAAPQACE -RVRSIMAQQVW-PHRLSSGFPADVQVAAKTGTLP-GVRNEAGVVTYPDGRGYAVAVFTRA -ESLRQPAVDAVIGRAGRLAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea wenchangensis TaxID=568860 RepID=A0A1I0LB53_9ACTN --------FEALFRVAGVTGWLHAADVDTGREI-GHGADEPLPVASMFKVPLLVELCRQAD -AGLLDPAERVTVPAGDRSSPTGVSAMLDDVTMSLRDLAYLMIAVSDNASADELLRRV-GR -EAVNATLEAYGLSVTRVRRSSREIDRAFDPSWGNAGSPRELTRLFGLIWRDEIASAASCA -WMRGVLNAQVW-PHRLASGFPDDVAVSGKTGTLPT-LRTESGVVEYPDGGRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora spinosa TaxID=60894 RepID=UPI000C6F3147 --------------GLPGRAGFAAWDLDEQEPV-LVDAEQVVHAASTIKVLIMIAALRAVQ -EGRIGLDEYVELPAE-RVGGFGILRELLSVTISLRDVITLMIVISDNAATNAVIDAV-GF -EAIRDCAADLGCTATRVERRLMDPNAH----GRNETTALDQARVLDALARGAALPPDLTE -HALEVLSKQQV-RDRLPALLPDGAQCWNKTGELL-GLRHDVGLIGAD-RPQAVVAVLVDE -LTDER------------------ ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=A0A2R3SDP2_RHOHA -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSTDQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. K4S16 TaxID=1316147 RepID=UPI0011ED1A9E ---EAAERIETAFRSAGVTGFLHVVDMDTGREV-AVGADEPVVLASVFKVPLLVAFHRQAA -DGVLDPTEQVVLRPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVMERV-GL -DAVNATAADLGLRRTVILGNGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPAGSA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS -TLAVLPEADAVIGTAARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ADI92-24 TaxID=1522756 RepID=UPI000F54E840 -------------------LHVAELHRPSAQVV--IDPDEQLPLGSVYKVPLMVAFCRLAD -AGRIDPCRRLTLEAADRVAPTGVSVLHDPVTMSLRDLVTLMMTISDNTAAAAVLRAV-GP -DVVDAVCRDLGMPDTRIHGGVVSTFSVYDPAFKASSTPADMARLLRAIWTGEAASDDRCA -FMRDVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. KR-1 TaxID=2662757 RepID=UPI0012D2D687 -------------AGFAGVVGLRVTDLAGTELA-AWNAGRVFPAASTIKVPLLVLALREAQ -AGRLDLSGRVVMQLDDRVPGAGVLHELDGGLLTWRDVLTLMIIVSDNTATNLVIGRL-GV -GAVNAWLAAGGLTGTRLVGKLEQRNEAQRCGERNATTARDQTALLRALVAGQLLDEAHTA -LALDILGRQQY-RDLIARHVPCGYRSATKSGELH-GVHHDVGVLFTP--RPLLVALLSEG -GTDPREPENA------------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 44-61 TaxID=1895838 RepID=A0A1Q3THH5_9SPHI --kKLEAELRKAITGFNGAIGIYVKNIKTGETV-AINADTVFPTASIVKVPIMMGVMDKMQ -KGELHYDSTHIYKDSLLYEGEDILGSFKDGEIALKKIIMLMLTTSDNTASLWLQKLAGTG -TRINALMDSLGYINTRVNSRTPGREEIRKIYGWGQTSPAEMGRLFEQIYQNKLFTPAACE -RIMRCLGRNFWDEDEAISMTPPYIEVFSKNGCVD-ASRNEALLVNAPNR-PYIFCIFTKN -NKTHANEAWTLTRKISSLLWDYf ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus hoagii ATCC 33707 TaxID=525370 RepID=E9SYY6_RHOHA -----------------------------GVDV-GVGADDPVVTASVYKLPLFVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CS159 TaxID=1982762 RepID=A0A209CB89_9ACTN ---ATAARLDAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. ACPA4 TaxID=2028571 RepID=A0A2A3FBB4_9NOCA ---SAQQEIAAVLAEAKTDAFVHVRDIDSGQEF-GYGADDGVILASVFKIPVVLEYARAVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFIYNRL-GL -DNIVSTLRSLGLEKTNLVRDCRGLFKVMDPSRTNSSTPREITQLLAAIWRDEAGPASACD -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVTYPDGKRYAVGVFTKS -HEKRAPKIDASIGTVGRIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) TaxID=518766 RepID=D0MKL8_RHOM4 --------FGRIEHRYELTLGVAAHNLTTGASV-FYRADTLFPTASVIKLAVLVELYRQYE -QGYLSPQDTVVLTAGRIYPGSGVLQHLSVPRLSLQDAAVLMIILSDNTATNLVFDRL-GP -DSVNATLRSLGLQRTRMLNKPFGFSTNTPEARRGMGTPRELMQLMIAMARGRVVSAEASR -EMIEILKRQQW-TEMAPRLLPDSLQLAHKTGAIST-ARCDVGLIFSPRD-TIAFAVMTDH -IKDPDQVGNLAVAEAVREVYE-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4S431_9FIRM ----LAQVLSAYLSTLRGTYGVAIVDLTTGATA-SVGGDRVFVAASTFKVPLAMYIFSLVE -RGEADLAEPLYYVPADWEGGTGILHGAVPGDYTVAELVNLSLTVSDNIATNMLLRRF-GE -QNVFAYMRELGGTVTNLPTG----RR--------ATTPRDMARYMEIAYRRAAREDGGYR -TLLGLLTQTAF-RDRIAAGAPAGVPVAHKIGTLP-AMVHDVGIVFLPGR-PFAIALFSEG -VS--EPVAAARLADITRLVSDY- ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=A0A0B1RBA7_9NOCA -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TTVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLEAVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Carnobacterium maltaromaticum TaxID=2751 RepID=UPI0011458BD6 ------------------------------------------------------------- ----------------------------------------------------MLFDQLGGP -AGFQKELEKLGDHTTESVRYEPELNEAIPGDCRDTSTPKAIALDLKKLTADKTLAPDKLT -FYKKQLVENKTGGNLIRAGIPTDILVGDKSGAASYGTRNDIAVLYPPDRKPIVLVIFSNK -TNKDDAYQDELIAKSAKLVGDYf ->[subseq from] Beta-lactamase n=1 Tax=Prevotella copri CAG:164 TaxID=1263102 RepID=R6CNL5_9BACT -------------------------------------------MMSVFKVHQALALCNDFD -KKGLSLDTLVKINREKLDPWSPMMKDYSAPVLTVRDLLRYTLSQSDNNASNIMFKNMLNT -AQTDSFIAKIPHSSFQIAYTEEEMSADHDKAYSNYTSPLGAAMLMNRLFTESLISNEKQD -FIKNALKECKTGIDRIVAPLKEGVVIAHKTGSGVNEAQNDVAYICLPNKVCYTLAVFVKD -FKGNEPQASQFVAHISAVVYS-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Rhodococcus sp. Br-6 TaxID=1522141 RepID=A0A2I9DW06_9NOCA -----------------------------GVDV-GVGADDPVVTASVYKLPLFVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0009C006FA -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSTDQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A0F985B -----------------------------GVDV-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSTDQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2D5NFU9_9BACT ---ALRERLSARLAQFDGDVGVYVRHFEHDQTV-EIAADELFPTASMIKVPILAALLHRVD -SGELDYHEKLTYTSDRLYAGEDLLGSFASGEVTIDKLAFLMITTSDNTAALWCQELAGTG -TAVNAWLEQQGFLRTRVNSRTPGREAARARYGWGQTTPREMCELLARVRGRRLGSAAASE -EMARALGRIYW-DGEALASLPPDVATMSKQGAVN-ASRSEVVLVHAPHGD-YAFCCITNR -QTQSDNQGFVLLRDVSRIIWEHf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=UPI0009A11B4D -hpQARDRIRAAFAEAGVTGWLHAVDIDSGAQI-DAGADRPVVTASVHKLCLLVALHQQAE -AGRLVLTEQTECPRDGRTAPTGLAAMLDAARVSLRDAAYLMVAVSDNTAADLLLERV-GL -DAVNDTTRRLGLTRTHATQTFREFLAAVDPARTNRSTPRDMTRLLGAIWRDEACTPEHGA -AIRRLLGLQVW-PHRLASGFPDDVLVAGKTGSAPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus oceanisediminis TaxID=665099 RepID=UPI00119D4348 ----------------------------EDRII-EFNSTEVFRSASLIKLPILFEALRQLE -EGILQPDRLLSVRQEDKVGDTGVLQAMNTQQITIHDLLTLMIIVSDNSATNLVIDLI-GM -APINSTISKIGMKNTILKRRMLDFKAA-QAGNDNFTTSADIVLCLKEAIEGQWLKEQSRD -RFTALLLQQQF-KEKLPAYMDQSMEIGNKTGELA-GIEHDCAFITYGDKR-AYAAVLIDG -LE-DNETGKSIIRQVGKQI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Lentibacillus halodurans TaxID=237679 RepID=A0A1I0XHB0_9BACI ----LEEEVLSIVEEVSEEGDVSIFIDTSEGEI-GVNETEVYSAASTIKVPILVEAIRQAE -QGNLNLDEKIEIDSSDIVGGGGILNDLSENQMTLRDLLTLMIIVSDNSATNMVIDRI-GM -DSVNETCMEMGCEQTKLQRYMMDFSSP----VDNLTNAKDMARILKAIDEANIVSQEGRN -EILRIMREQKL-T----AGLPTEVTFASKGGSLSPQIRHDVAHVTDGNET-AYVAVLTSG -LS--KPTARKAMNKIGEKMAD-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0007CD66D9 -----------------------------GVDI-GVGADDPVVTASVYKLPLFVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces aureoverticillatus TaxID=66871 RepID=UPI0013D95E63 ---NTATRLQEAFAEAGVTGRLHALDIDSGAEL-GAGADQPVVTASVHKLCVLVTLHEQAA -AGLLDLTEQVECPVDGRTSGPTGLAAMLDPVLSLRDAAYLMMAVSDNTAAELLLERV-GL -DAVNATTARLGLTRTRAVHTFREMFAALDPARTNHSTPRDMTRLLGALWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ARATLPSADAVIGTAARMAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI000D599FFC ---ATAARLDAAFADAGVTGWLHAVDVDSGTQV-GVRADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Rhodococcus sp. (strain AD45) TaxID=103808 RepID=A0A0D8HW74_RHOSX ---SAQQEIAAVLAEAKTDAFVHVRDIDSGEEF-GYGADDGVILASVFKIPVVLEYARAVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFIYNRL-GL -DNIVSTLRSLGLEKTNLVRDCRGLFKVMDPSRTNSSTPREITQLLAAIWRDEAGPASACD -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVTYPDGKRYAVGVFTKS -HEKRAPKIDASIGTVGRIAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=bacterium (Candidatus Blackallbacteria) CG17_big_fil_post_rev_8_21_14_2_50_48_46 TaxID=2014261 RepID=A0A2M7G9A5_9BACT -------CLRAHLEKLEGQAGFCAENLHTGQKI--CHGDRRFLSASTIKIPVLALYWADRE -KGHF-AETEYLYQSQDWVEDSPYFENIAPGSIPWDEIARQMIIISDNTATNLLIQRL-GL -KRIQAWLNANGFKTTRIERYMMDLEAR-AQGIDNWTSPSEMCRLMKKLVKGEVTEPGSQQ -AILQTLHQQQD-LEKIPHFFSAPILVANKPGELP-GTRSDVGYLHNAQH-EIVMALFTDQ -LK-NEATSDLWLATLAQILWR-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia fluminea TaxID=134984 RepID=UPI000C70F9D4 ---------------------LHARRCDSAGEV-SVGGNDRVVIASVYKLLLLAAFLRQVD -HGLIDPAGRLTIDPSDCTPPTGLAALHDPVTLSRRDLAMSMMTVSDNAAADVLLGEV-GL -AAVGELVHELDLPDTRIIGGTADQHRAYDPSYASATTPEEMTRFLWKLWSGDILSTASTE -FARTVMSKQVW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter sp. NBS58-1 TaxID=2595005 RepID=A0A5B6TTW6_9BACT --kQLTQKLQTLTKDFQGEVGIYVRHLKTGKTV-AINADTLFPTASIIKVPIMVAMFDKIE -RNEIDPKTILRYRDSLYYAGEDIVGSFKDSSVALSKIQMLSITTSDNTASLWLQQLAGTG -TAINAWLEKNGFTYTRMNSRTPGRRPNWEKYGWGQTTPREMATLVTMIREGKAVSPAASE -RMYRNLGRIYF-DSEALSQIPPFVHTASKSGAVNR-SRSEVVLVNAPHGD-YVFCIITKN -QKDESNAGYALIRAVSKTLWQHf ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus pentosus TaxID=1589 RepID=A0A2S9VYZ9_LACPE ---QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK -EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF -DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE -AMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED -GDQ--NDQIDAMNRLGSLLYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5QD35_9BACT --eTLQQNCQRIMSESKAAYAVALLDYEDGFRF-TIDADRPFHAASTIKVAILLAVAKAFD -EGRIRPDDTLHIRNRFLSARTPFRHRMVGRTAKISDLAEWMIVSSSNLATNLLLDYV-TI -EYALRVLRDAEVSGINLRRGVDDTKA-HANNFNNETTGEGLLKLFSTL-RGDFLSKTGRD -FVINILLQQRF-NSMIPAPLPPHASVAHKTGEIST-ACHDAGIVYLPEREPYILVVLTEV -MAES-NGRRESIAKISEAVF--- ->[subseq from] serine hydrolase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI0007A371BB ----------------------------SAGEV-SVGGHDRVVVASVYKLLLLAAFLRQVD -HGLIDPAGRLTIDPADCTPGPTGLAALLDPVLSRRDLATSMMTVSDNAAADVLLGEV-GL -AAVGELLQELGLTDTRIVGGTADQHLAYDPSYASATTPEEMTRFLWKLWSGDIVSTASTE -FARTVMSKQIW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI000A11CEDB -----------------------------GVDV-GVGADDAVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTTLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=UPI0005692356 ----IEERLRAVFAGAGAEGVLHAVDIDGPGEA-GYGADEPVVVASVFKVLLVLEFARQSA -AGQLDPRERVRVTSEHRLGGWGTGGCLDDVELSLRDLAHFAMAVSDNTAADLLMERV-GT -DTVAMLAKELGLENTRIVGGPRQVLEVYDPARTNASTPREMTRLLRMVWRDEAGPPEACA -QVRELMGRQVF-RHRLAAGFGDGVRVAAKTGTLP-GLHNEVGVAEYPDGGRYAVAVFART -PGANRTETDVAIGAAARTAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. AJ005 TaxID=2652443 RepID=A0A5J6YSX9_9DEIO -------------QGYVGEVGLRVCDLLGRELF-ALNPERVFPAASTIKVPLLILALHWAQ -AGRLDLESRVTLEAIDRVSGAGVLHELEPGLLSWRDVLTLMIIVSDNTATNLVIGRL-GV -DAVNDWLTTHGWTETRLVGKLEERNAAQLRGERNRTTAADQTDLLGRLVRGELLDTAHTA -HALNILERQQF-RDLIGRGLPRAYSLASKSGELD-GVHHDVGVLYTP--RPLVIALLTQG -GTD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. SDU3-2 TaxID=2651870 RepID=UPI00128BFAFB --------------GYVGEVGLLVTDLAETELF-ALNPDRSFPAASTVKVPLLVQALEEAQ -AGRLDLSARVTMTAQDRVPGSGVLHELGAGLLTWQDVLTLMTVVSDNTATNLVIGRL-GE -GAVNAWLALRGLTHTHLIGKLERQNEAQRRGERNRTSAQDQVALLGRLVRGELLDPPHTE -LALSILTRQQF-RDILGRHVPRDYRVASKSGELR-GVHHDVGVLFTP--RPLVVALLSQG -GL--------------------- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI0009BCDD9F -----------------------------GVDI-GVGADDPVVTASVYKLPLVVAFCRLVD -AGDLDPREQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAMSDNAAADELLRRV-GV -DRVNETMRSLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTMLLSAVWSGAVLSADQTA -FVRAVMASQIF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGQAARTAIA-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NEAU-LD23 TaxID=2486417 RepID=A0A3M8VR32_9ACTN ----ARRTIRGLFADAGVRGWLHVADLHRPEACvAIDPDEPVPVGSVYKVPLMVAFWRLVD -AGTLDPCERMTLGPSDRMPPTGISILRDDITVSLRDLVTLMMSVSDNTAADVLLRRV-GT -EAVDEVCRDLGMPDTRIHGGVATTFAVYGPLLKSSATPADMARLLRAIWTGRAASADACA -FMREVMGRQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] serine hydrolase n=1 Tax=Desulfofarcimen intricatum TaxID=1285191 RepID=UPI0008348453 --hELKNKLEQMLKQEQGTYGVFVIDLKSGRAL-GVNPLEPFHAASTFKLPLNVYLYKKIA -QGEVDPQNMLVYESSHYEGGTGQLQKPVGSSFDIETLSKYSIVYSDNVATNMLLTYL-GK -QNVKNYMRAAGGLVV--------------EDNKNITCPRDMALYMKELLDFNAEQPAVTS -KLIDHLENTVY-NDRISKLLPDNIKVAHKVGNWPTGTYNDVGYVQHPEN-PYIIAVFSKN -TP-GINSAFGVIQRVSKTVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Aphanothece cf. minutissima CCALA 015 TaxID=2107695 RepID=A0A2T1F091_9CHRO -----SQQWARLAAQKGLTASAFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD -RGKLRWNEPMPLTKEVVGGGAGWMAKPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK -TELNSRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD -LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQMPNGQRAVLAVMVKG -PFND-PRSAELIRSMAGAVTK-- ->[subseq from] Secreted beta-lactamase n=2 Tax=Streptomyces pristinaespiralis TaxID=38300 RepID=B5HHK2_STRE2 -----EERLRAVFAGAGAEGVLHAVDIDGPGEA-GYGADEPVVVASVFKVLLVLEFARQSA -AGQLDPRERVRVTSEHRLGGWGTGGCLDDVELSLRDLAHFAMAVSDNTAADLLMERV-GT -DTVAMLAKELGLENTRIVGGPRQVLEVYDPARTNASTPREMTRLLRMVWRDEAGPPEACA -QVRELMGRQVF-RHRLAAGFGDGVRVAAKTGTLP-GLHNEVGVAEYPDGGRYAVAVFART -PGANRTETDVAIGAAARTAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E1KRX3_9PLAN ------TQLDSLAKSFAGRLGFYAKDVRGGATY-AFNDDQRFPPASVIKLPVMIQLYRQAA -LGHLQLEEKHRLPIDISTHGTGVLKARDGLILPLREYGRLMMIHSDNMATDLVIRTV-GT -KSTNQFLDDQGCQSTRVSLELGRWHYYSDSLENNVCGPRDTGLLLERLYLGQLANRSDTD -EMLNLMRASTH-KQTIARYLKPGVRVANKYGGSRR-IAADVGIVELPER-PVVIAAFAIS -NAADDRSGRGILARMSRLVIA-- ->[subseq from] Serine hydrolase n=1 Tax=Panacibacter ginsenosidivorans TaxID=1813871 RepID=A0A5B8V9E4_9BACT --tKLQSQIKFLLQGFHGNVGVFVHDLKHNKIV-ALNADSVFPTASIVKMPILLGIMDKIT -TGQLNYHQRLTYTDSLFYDGDDILSSFKDSAIELSKVMMLMLTISDNCASLWLQGLSGGG -KRINELLDSLGFKNTRVNSRTPGREADRSQYGWGQTTPREIAGFMERVVNNQLLDKASDE -KMLRLLGRQYW-DEEALSQIPPGVFVADKNGAVDE-SRNEVVYVNSNNN-PYIFSIFSKN -NADTNNEAWVLTRKLSSLLWQYy ->[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus pentosus TaxID=1589 RepID=A0A2S9VJN1_LACPE ---QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK -EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF -DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE -EMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED -GDQ--NDQIDAMNRLGSLLYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas phototrophica TaxID=1379270 RepID=A0A143BLN5_9BACT ---TLRRTIDSIADGHRGVVGYSITNLETNEHL-ERRGDEPFSTASLIKVPILVALFDLAE -QQQLSLEDPVVLTAIDKVGGAGQLQYLRTPLLRLWDAAWLMTTLSDNTATNLVLDRI-KI -RRVWQKMEALGLPRTKVHSGSMTRIASSAKYGLGVTTPNEMAQLFTLLAHGKAVSPRADS -VMLDILEHNEDDSKLMR--FNYGVRAAHKTGDVDQ-SRTDCGVLYLPAR--VVACVLTRE -NVDKDSEGNAVIARIGQAVAAHw ->[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. AM16-9 TaxID=2302960 RepID=A0A372V9K4_9FIRM --eKLRQQIEQRLSAVMGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD -TDAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI -GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE -DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH -V--SPPEFERAMQDITLMLYE-- ->[subseq from] Beta-lactamase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=A0A0D8J3S6_9FIRM --eKLRQQIEQRLSAVMGDACFYYENLATGVCF-GHAADKPVVAASVIKLAVLIEAFRQMD -TDAVRANEMFVIARTDKLPSCGALNYLHDGLVTFRDLCVLMTILSDNTATNLLIKRL-GI -GNINDTLRMLGAEKMTLNRLLFDREA-SSRGIENYITAREAGLLLKRLYDGEAVSGPASE -DMLSILKDQRL-NGKIPFLLPHSVKIAHKTGEDD-GITHDVGIVYA--RQPFIVCFCGEH -V--SPPEFERAMQDITLMLYE-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. WAC 06369 TaxID=2203193 RepID=A0A429G0S2_9ACTN ------------FRDAGVTGHCHAVDVDTGRDV-GVRAGEPVVLASVFKVPLLVAFHRRVA -AGTLDPTEPATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADYLLDRV-GL -AAVNAAAAELGLPGTHVSGSGREMLDVRPLDPTSRSTPREMTRLLSLIWRDEAAPPAECA -AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT -PVAVHPAGDAVIGTAARMAVEH- ->[subseq from] serine hydrolase n=1 Tax=Pontibacillus yanchengensis TaxID=462910 RepID=UPI00136D0925 ---RLENEVTEIVSKLDGNASVVIQTI--NGTI-AMNEKEVMPAASVIKIPIMMEAFRQAK -TRGVDLSATVTIPQHNKVGGAGVLQFLSQDAFPLHDLVTMMIIVSDNVASNAVIKHI-GI -GNVNHLIEELGCSNTKLRREFMDLKAQ-EQGLDNTTTAEDMVKLLEQLTLQD-------R -EMVEILKGQQL-TSQLPAHTYEDLEVANKTGELD-GVNHDVGILIDSHQ-TVYVAVLLND -VR-DTVEGQRAIADIGNQVMQY- ->[subseq from] Uncharacterized protein n=1 Tax=Bdellovibrionales bacterium GWB1_55_8 TaxID=1797386 RepID=A0A1F3T2Y2_9PROT ----LDQEVRRLERAYPGKFGLYMKRLSDDRVF-SHRGSARWYIASGVKVPIAVEALVRAS -EGKISLSDRIDLSEDDYVDGAGQTNYHPPGSLSIRYLLQQMLVYSDNTAADLLLRKV-GL -QSVNERVKVLAPEAFGEITELSEVRRAYYRTGVNSATLEGYARILERIAKNEVLDPLHTK -LLLEWMDGVKTGRNRLIAAFPNTVVFAHKTGTQFQ-RICDFGVARKRTRKGVVIAACVQG -LP--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter radicis TaxID=2172650 RepID=A0A2T9K9L0_9CAUL -----SLKLTAIAERAPGDLGVAVQDLTTAQRA-TVAGDHLFPLAGIWTAALGAAVLAEVE -AKALSLRETITIEDVDLSPPSGVADAWPSRRWTVEELLKHAVAGGDNTAADVLMKRIGGP -GAVTAWLDLKKVENLRVDRYARQLLPDYLADPHDSTTPLAAVRFLEALNQAELTSQDGRR -RMLRMMEAAA--GERLRPALPAGARLAAITSATPTAADNVLAMVRLKDGRRFALAILLKA -SPLEEADRDALMLEVTRTVLQ-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus horneckiae TaxID=549687 RepID=UPI00082CE5C7 ------EEVIRRSSLCKGRVGLLIES--ENKRI-EINSKMKFPSASLIKVPILIECFRHSE -RGILDLDQYIPMTASNKVKGAGVLHALSSDILKVIDLMTLMIIVSDNFATNLLIDLV-GM -EKINCGFKELYLKNTELNRKMMDFS-AWKKGVDNYTTASDMITCLKELDQNQFLSKRYAS -MAKDILENQQF-NNKLSDQIDDRFKVANKTGELF-GVEHDCAIIQYEKR-SIYAAVLIDQ -LINP-KDGRQTLSSIGQLISQ-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus sp. 349Y TaxID=2653176 RepID=A0A653MGQ3_9BACI ---DLREDLMKVIHECPGSVSFTILS--NDESL-SWEENRRISSASLIKLPILMAAFEQIQ -TGSLNGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLTLMITVSDNTATNRLIELI-GK -DSINRLCLAWNLKRTFLNRKMMDFRS-LEMGQDNWTSSMDVVSCLKGINEG-AFEEISRR -KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDE -LHAP-EDGRKAISRIGKLVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Ru73 TaxID=2080748 RepID=A0A2S4XQC1_9ACTN ------RTIREMFADAGVRGWLHVAELHREARV-TVDPDEPVPMGSVYKVPLMVAFCRLAD -AGEIDPRRRVTLEPSHRIAPTGISILQDPVEMSLRDLVVMMMTISDNTAADAVLRAV-GA -TAADAVCRELGLPDTRILGGVAETWAVYDPVSKASTTPADMARLLRAIWTGRAASPERCA -FMRDVMGRQPW-RHRLASGFPDDVTVSGKTGTFG-AMRHEAGVVELADGSAYTAVVFTRA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C1JKH8_9CHLR -------------------ASIAVVHLETGASA-TVNGDRIAVPASLYKVGVLVEAFRQIE -AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV -DRVNANNQRLGLSNTRY----------YIDDRPDTTTAADMARLLSLLATGRLAGVEATG -QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN -RP-NAMKGENAIVQVARSVHAYf ->[subseq from] serine hydrolase n=1 Tax=Mycolicibacterium porcinum TaxID=39693 RepID=UPI000A996A81 ------------------------------------------------------------- ------------------------------------------------------------- --GITAFARSIGDERTRLDRWEVELNSAIPGDPRDTSTPAALAAGYRQVLAGDALSPPQRR -QLEDWMRANQT--SSVRAGLPEGWTTADKTGSGDYGSTNDVGIAYGPDGQRLLLAVMTRS -QADDADNLRPLIGELTAA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia hierapolitana TaxID=1128676 RepID=A0A561T5D6_9PSEU ---ELEREIRRTFADAGVHGRLHAMPLGGDREV-GVDPDEPVVMASVYKLPLLVAFCRRVD -AGELDPREQVTVDPAGRTAPTGLSVMRDPVTMSWRDLACSMIGVSDNAAADVLLRRV-GL -DHVNETLSDLGLERTRVLGGTADVYRAYDAVLASATTPREMTRLLAAVWADRAASPQQCR -FARELLGAQAW-QHRLRSGFPVGVRVAGKTGTLA-AVRNEVGVVQFDGERPVAVAVFTRA -ARAELPRADAVIGQTARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI00040E4062 ----LAQRIEALSNADSTRYSVYAAFPEENSTP-YLYQSEPMRSASMIKVFLLADAMEKVR -DGKLSLDSTITLHASDKVGGAGILCGYANGSLSLDTVLRLMITESDNTATNLVIDLL-GM -DDINAYIQRNGYYDTKLARKMMDFAA-VNAGLDNYTSVQDLGSFFLKLYQHDCVGFEQDE -IMLSYLKGQTD-KECFPAALP-GAVIAHKTGELG-GLYDDGGIIYVDNRT-MILVIMTEH -YSSR-YRAIETMKAMAQAA---- ->[subseq from] Beta-lactamase n=1 Tax=Rufibacter sp. DG31D TaxID=1379910 RepID=A0A0H4VLQ3_9BACT ---KLIQKLQALTQRFEGDVGIYVRHLKTGKTV-ALNADSLFPTASMIKVPIMVGMFDKME -RGEIDPKAILRYRDSLFYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQQLAGGG -AAINAWLEKNGFAHTRVNSRTEGRRPNWQKYGWGQTTPREMANLVTMIREGQAVSPAASE -RMYRNLGRIYF-DSEALSQIPPTVNTASKSGAVNR-SRSEVVLVNAPHGD-YVFCIITKN -QKQDNNAGYALIRAVSKTLWQHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BF850CD ------------TKWKQSNNGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID -EGILTLTSVIQRTEKNTVGGAGVLGALPRLTIKVEELLTLMIIVSDNTATNELISLA-GF -EKINECARNMGLKKTVLNRYMMD-ETAVKQGLDNYTCASDVVECLREIYEGNLLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LSEN-EQGRRLIADIGYL----- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E6WQV9_9CHLR -------DINLIIKDVPAVVGVAARHIHTGKNY-YNKADDIFFTASTLKIPLIFELYRQVD -KGIINPMQRISVN--DKSPGSGVLKDSIGINPTIYDLATLMIIISDNTATDIIYKII-GK -DNLHKTLLDLNLKSTHLPMTCKELLYALSEDKSDVSSPNDMINLMEIIYKKELLTKKSSD -IILDIMYRQQA-KTIIPYFLPSNIKTFHKTGGVTS-VRCDVGIVNGKSG-PYSIAIMAKD -VK-DDKNIDLSLARISEAVYHFf ->[subseq from] Beta-lactamase class A n=1 Tax=Lactobacillus diolivorans DSM 14421 TaxID=1423739 RepID=A0A0R1SAW5_9LACO -------AEKQCIKSSAGKTSVFVDSLNNGQLI--VTNNQVQRSASVIKLFIMIDTFHQIQ -TGRLKLNQLVSFPKSDRVDSTGELANQAVHQVSVSELLKLMIRNSDNSATNVLIDHLGGL -NIVNEEIRRLNCNHTKLQRKMLDYQ-ALQSGKDNLTTSKDIGKILVRLYHHHVLRNPYDS -AMLQLLRHNAN-QSKLPALINQKSVIYNKTGEFQYGVQNDAAIIKKGNQA-FIVVVLSEN -GVQT--KQINAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 50-39 TaxID=1895841 RepID=A0A1M3H3Z5_9SPHI --rKLEEKLQALTDTFHGVAGVYVRNLRTGKEV-TINADTVFPTASIIKVPILVGIFDKIQ -QGEFPYHQPLVYRDSMSRKGSGLMQFFRDSTTDLQTAITLMITHSDNAAAVWCERLAGGG -AAINAWLSAHGFEYTRLNARTAGREQARQQYGWGQTTPREMARLVSMIRNDAVVSPAASQ -TMYRIMTHVFW-DEYALYPLPPYVQAASKQGMVDD-SRSEVVLVNAPHGD-YVFYVATKN -NKDQENEAWQLARRVSALLWDYf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacterium sp. TaxID=1872119 RepID=A0A2G4JGC6_9BACT --------LARTVAEFPGHAGIWVKHLTTGESA-GIQDTELFNSASVIKLPVLVLAFQMAD -RGELKLDERITITKEDLRGGSGIFRYHDTGLPTLRDVLLQMVITSDNTATDLSIAKVGGV -AKVNAWLRDKGYAGMRLVQTTGELFTSDRAYWLGEISARATGQMLEAIEKKTMASPASCD -AMLRMLRAQQAGQRRLNHYLS--VPVAHKTGDFPPVLANDVGIIYARSG-PLVVSFLGNA -ITGNYGEAEDRIGRFAQRLVEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus pyridinivorans TaxID=103816 RepID=A0A495NEP1_9NOCA -----------------------------AATL-SVRGDERVVLASVYKLPLFLAFCAEVD -AGRLDASGQLRIVPSDCTPPTGIASFRDPVTMSRRDVAASMMTVSDNAAADVLLGEI-GT -TTVEELLARLGLTRTRIIGGTADVYQAYDPAYTSATIPEEMTRLLETVWSGSVLSPESTA -FAQQVMRAQVW-PHRIASGFPRGVAIAGKTGTIGI-IRNEVAVVEFPGEYPIAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. CEV 2-1 TaxID=2485153 RepID=A0A3N1TNT1_9ACTN --------IRSMFDDAGVRLHVAELHRPSAQV--VIDPDEQLPLGSVYKVPLMVAFCRLAD -AGRIDPCRRLTLEAADRVAPTGVSVLHDPVTMSLRDLVTLMMTISDNTAAAAVLRVV-GP -DVVDAVCRDLGMPDTRIHGGVVSTFSVYDPAFKASSTPADMARLLRAIWTGEAASDDRCA -FMRDAMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Pontibacillus yanchengensis TaxID=462910 RepID=UPI00136E94EA ---RLENEVTEIVSKLDGNASVVIQTI--NGTI-AMNEKEVMPAASVIKIPIMMEAFRQAK -TRGVDLSATVTIPQHNKVGGAGVLQFLSQEAFPLHDLVTMMIIVSDNVASNAVIKHI-GI -GNVNHLIEELGCSNTKLRREFMDLKAQ-EQGLDNTTTAEDMVKLLEQLTLQD-------R -EMVEILKGQQL-TSQLPAHTYEDLEVANKTGELD-GVNHDVGILIDSHQ-TVYVAVLLND -VR-DTVEGQRAIADIGNQVMQY- ->[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=A0A1W6NG22_LACBR ---EIKKDIGATVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK -EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF -QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD -EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED -GEET--DQLAAMNKLGLM----- ->[subseq from] Uncharacterized protein n=1 Tax=marine sediment metagenome TaxID=412755 RepID=A0A0F9QNK4_9ZZZZ --kKLEKGLRELVGEFNGDVGIYVYNLKTGKVA-EINADTIFPTASIVKVPILVGVFEQIH -NGKLHLNDSLLYTAERVYGGSGLMQFYKDSTTDIRTLASLMITVSDNTTALWCQELAGGG -EAINKVMADLGLKSTRVNSRTEGRTIDWEKYGWGQTTPREMVSLLLKMRNRELVDEVSSD -EMYRLLTNSFYTDYSL-SQIPPYVQTAAKQGMVDR-SRSELIMVNAPNGD-YAFYIATKN -NQDEDNEAWQLQREVSAYLWHYf ->[subseq from] Beta-lactamase n=2 Tax=Flavihumibacter sp. ZG627 TaxID=1463156 RepID=A0A0C1I8Y3_9BACT --------VTEFNKQPQAVFAVAVKDLSSGNTF-LYNDQLEFHAASTMKTPVLVEAYKQAK -EGKFSLSDSMLVKNSSIVDGSLYSYSKIGARLPISDLLYKMITKSSNLATNLIIDLV-KA -PNVNASMRKLGASKIQVLRGVEDGK-AYAKGLNNITTAYDLMLIMEAIANGTAVDKKSGE -EMIKILMDQYF-RDIILAKLPTDVKAATKSGNIT-AVCHDSGIVFLPDGRKYVIVLLSKG -IPQ-QSVATEILSTVSRIVYDH- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A3D8X5S5_BACME ----------------RSNNGLIRIHIEGKESI-QVNSFIQQRAASTIKLLLAIEAFRQID -EGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVKELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGVDNYTCASDVVKCLREIYEGNLLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DQZ0_9PSEU ---DLEREIRATFADAGVHGRLHAVPLGGSREV-GVDPDEPVVMASVYKVPLLVAFCRRVD -AGELDPREQVTVEPAERTAPSGLSVMRDPVTLSWRDLACSMITVSDNAAADVVLRRV-GL -AAVLEVLHDLELRHTRVHGGTAEVLRAYDAALDSATTARDMTRLLAAIWGDRAASPGQCA -FARDLLGAQVW-SHRLRSGFPVGVRVAGKTGTLG-AVRNEVGVVEFDGERPVAVAVFTRA -ARAELPRADAVIGQAARLAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E3MSF0_9PLAN ------HELDATAKKFAGRVGFFVRDLASGADY-GWNPDERFPPASVIKLPVMIELYRQAA -AGRLDLDQRLRLPTDISTHGTGVLKKRDRPVLPVREYADLMMIHSDNMATDFIIRTV-ST -ATTNRFLDAQGLRNMRVSLELGRWHYYSDSLQNNVCAPRETVLLLERLYKGQLTSEKHKQ -AILGPMRASTH-KDTIARHVKDGIQVANKYGGSQR-ISADAGIVEITDR-PIAIACFALA -NDQADRSGREVLAEMCRLAI--- ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2D7NVR0_9BACT --eDLDLKIKLLLEQIEGDFAIAFQDLHRKENNfFLNENKKFHAASTMKVPVMIEMYHQAS -QGKFSLTDSILVKNESIVDQSSYEYSQIGKKMTLFDLMYQMIILSSNLATNILVEEI-GS -KNVTASMKRLGAYNTEILRGVEDQK-AYDLGLNNVTTAKDLMTILKSIAVASSEITKDQI -AMINVLKAQEF-NDIIPRFLPLDVEVAHKTGSIT-GSHHDAGIIYLPNGE-IYILVLLSK -NLKDFNQGTLTLAKISKLFYEH- ->[subseq from] DZANK-type domain-containing protein n=4 Tax=Lactobacillus brevis TaxID=1580 RepID=U2NZB4_LACBR ---EIKKDIGATVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK -EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF -QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD -EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED -GEET--DQLAAMNKLGLM----- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00112BC0CF -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSSE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG -LS-DNEQGRRLIADIGYLL---- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga pinensis TaxID=79329 RepID=A0A5C6LW49_9BACT --hKLEKGLREIITGFQGDVGIYVRNLKTGRYV-DINADTIFPTASIVKIPILVGVFDKIE -KGELTYHQPLIYRDSIKYGGSGLMQFFKDSTTDLSVLVALMMAYSDNTTSLWNQALAGGG -QRINELMAQYGLNVTRVNSRTPGREAIRNVYGWGMTTPREMAELLVKIRNGEVISQNASS -RMYRLMTHGYY-DEVGLSQIPPYTQAAHKSGSVD-ASRSEVILVNAAHGE-YVFYVGTKN -NKTSENEAENLIRKVSAYLWEYy ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A3D2XD55_9BACT --kRLQQKISQLIQGFNGDIGIYVHDLKKNKTV-AMNADTVFPTASMVKVPILVGIMDKIS -KAELDYHQTLTYKDSLLYAGVDILGSFKNDEIELSKVMMLMLTTSDNTASLWLQGLAGTG -TRINEIMDSLGFKDTRVNSRTPGREANRTQYGWGQTTPKEMAQLFERIAAKQILGDTASE -KMLKLLGRNYW-DEEGLSSIPAGIFVASKNGAVN-ASRSEVIYVNG-GEARYVFCICTKN -NKDQNNEAWVLTRKLSELLWNYy ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. FJAT-27238 TaxID=1679167 RepID=A0A0K9MLN0_9BACI ---ELEKRLSAIIGQAEGTWGVVVEEHGSAKRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRMDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLI-GK -DQIDQTMINLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGHLATGSFLSQRACK -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces gancidicus BKS 13-15 TaxID=1284664 RepID=M3DYC6_9ACTN -----VARIHAAFADAGVTGRLHALDIDSGDQL-GAGADQPVCTASVHKLCLLVALHERAA -RGVLDLAEQLETVPGERTAPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=2 Tax=Oscillibacter sp. 1-3 TaxID=1235797 RepID=R9LYG3_9FIRM ----AKERILEKIKTFPGQSGIYYQNLETGETW-GYGDKDPYLAASIVKLPLMAAILLWRS -RGETSFDDKVTIREDQKIPGCGAVQFLNGDVLTVGELCRLMIVISDSCATNALFRHY-GA -AAIRKAFLELGLAGTQFNREYWDEERE-KQGINNYFVPEEMGRLLRRMYDRTLVNAESSE -WLENILRQQQI-NHKLGGKLPMDFPMAHKTGDEED-KAHDVGIVFTKS--PFIACFAYVG -P--DMQDYEDFIRRAARMLAD-- ->[subseq from] serine hydrolase n=1 Tax=Segetibacter sp. 3557_3 TaxID=2547429 RepID=UPI0010589E0C --rKLERKLNQLITGFNGQLGIYVHDLKRNRIV-GISQDTVFSTASMVKVPILIGIMDKLN -RGELKYNQEIIYHDSLLYAGSDILGSFKSGEIELGKVIMLMLTTSDNTASLWLQNLAGTG -SRINNLIDSLGFKETRVNSRTPGRESIRSVYGWGQTTPKEMATIMERIVKGEIISDSLSQ -RMLRLLGRNFW-DDNAIAQVPADVFVASKNGAVNK-SRSEVLFVNGRGR-RYVFCVCTQN -NNNENNEAWVLTRKISKLLWEH- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=A0A0L8QRD0_9ACTN -----QRTIRGMFADAGVRGWLHVADLHRPAACvTIDPDEPVPIGSVYKAPLMVAFCRLAE -AGEIDPCRRVTLGPADRLPPTGISILRDPVTVSLRDLVVLMMTVSDNTAANAVLRLV-GT -AAVDEVCRALGMADTRVHGGVATTFAVYNPLSKASASPADMARLLRAIWTGRAASPESCA -FMREVMGRQAW-SHRLGSGFPDDVRVSGKTGTFGS-MRHEAGVIELPDGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC712 TaxID=1848329 RepID=A0A4R4WF71_9ACTN -------DFDALFRTAGVNGWLHAVDVDSGREI-GHGADVPLPTASMFKVPLLVEFCRQAD -AGLLDPAGRMTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR -KAVNTMLAVLGLHGTRVLQSCQEFNDALDPERTNRSTPREMAELFGLIWRNEAASAESCA -WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus planocerae TaxID=1737569 RepID=UPI000C7F656D -------------RGFGGEVGLVVSDLAGRELY-VLNPDRVFPAASTIKVPLLVQALGEAQ -SGRLDLRERVTVEAGDRVPGSGVLHELGPGLPTWEDVLTLMIVVSDNTATNLVIGRL-GV -EEVGAWLAEQGLSGTRLVGQLERRNEAQRRGERNRTTARDQVTVLGGLARGELLDPFHTD -LALSILSRQQF-RDILARHVPRGYRVASKSGELT-GVRHDVGVLFTP--RPLVVALLSEG -GDDPRE----------------- ->[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6WAB0_9FIRM ---ALAASLRQLMEKDSAKYQVYVFFPQWDEPL--VMGKDPQSSASIIKIFILGTAYELAE -QGQLDLNQQVTVHPLDMVGGAGVINGQSGAPYTVRKLLELMITESDNTATNVLMDAI-GL -ERIHHFMKEHGFHDSILQRKMMDYE-ALRAGKDNFTTAADAGRFFRLLREHKLVGEAADS -EMISILFGQTD-TECFPQALP-QARIAHKTGELS-GVYHDAGIVYDAND-SYVLCIMSTD -SRGR------------------- ->[subseq from] serine hydrolase n=1 Tax=Fibrella aestuarina TaxID=651143 RepID=UPI00141A3321 --tKLTQKLTEALRGFRGDVGVYVHHLKTGKTV-AINADTTFPTASTIKIPIMIGLFDQIE -KGKIGYQQEVVYRDSLHYDDGIVGSLKDGAKLPLSEVVMLMETVSDNTGSLWCQKLAGGG -IAINAWLDTNGFPQTRMNSRTPGREAYQKRYGWGQTTPRELADLLTYLRQGRAISPDASD -RMYRNLCRQFW-DNDGLSQLPVEVKVACKTGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKN -QKDETNEGFTLLRTVSALIWQHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0005C82F10 ----LENKIQEVMDLCNGRVSVAI-DLPT-QSI-QINGDRSYSAASLIKIPILLEGFRQSE -EGKISLCEMVTVPKEGRVGGAGVLAALSENLLTIEDLLTLMIIVSDNTASNLLIDRL-GS -NAIQELCNSLKLKHTKLHRKFMDFKA-MEQGLNNVTSALDMISCLKVMDNSPEFSQTSRE -KMLHILHQQQF-DNKLPSRMDREVFVANKTGELP-GIEHDCAILKLGNKT-AYIAVLIDE -LGEN-GSGKDTIALIGKLIFD-- ->[subseq from] Putative beta-lactamase related protein n=1 Tax=Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516) TaxID=278992 RepID=A0A0K2AUX2_STRA7 --------LHAAFADAGVTGWLHAVDIDSGAQV-EHGPDQPVCTASVHKVCVLVTLHELAA -AGALDLTERVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLGRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLSALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ARATLPAADAVIGTAARIAVD-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=mine drainage metagenome TaxID=410659 RepID=A0A1J5SM31_9ZZZZ --kHLQSSIQNLLTGFHGQVGVFVHDLKKNKIA-AIDADTIFPTASMIKIPILIGVMNKIE -SGELQYHQPLIYKDSLLYAGVDILGSFKNNEIELSKVMMLMLTMSDNTASLWLQSLAGGG -LRVNELLDSLGMKVTRVNSRTAGREKNRTEFGWGQTSPREMASLMEKISQGEVINQTASE -KMLRLLGRNYW-DEEAISQIPTDVFIASKSGAVD-ATRNEVLFVNGKHC-CYIFCICTKN -NKEPNNEAWELTRKLSKLLWEYy ->[subseq from] ClassA n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SZF4_9BACT ------------------------------------------------------------- -------------------THSPLRDANPNGNITVGDLLKYSLIESDNNACDILFKYIGGP -LVTEKYIHGLGIKDVAISQTEAKMMESEDNCMLNWTKPSAAVLLLETFLQNQMFSKNEVL -FLERAMADCKTGNNKLKAGLPKQVLFAHKTGSSGRNADNDMGFVVFPNGQYYTIAVFIMN -SRETDQENAKIMADISRTVYEYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00119EF3E6 ------------TKWKQSNNGLIRIHIEGKESI-RINSFIQQRAASTIKMLLAIEAFRQID -EGILTLTSVIQRTEKNTVGGAGVLGALPRLTIKVEELLTLMIIVSDNTATNELISLA-GF -EKINECARNMGLKKTVLNRYMMD-ETAVKQGLDNYTCASDVVECLREIYEGNLLKKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LSEN-EQGRRLIADIGYL----- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E1WA46_9CHLR ---KLNFSVNNIVNEFKGLCGVSIYDPDTNWYL-GINDEMIFPTASSIKIPILIKLLSDAD -KKLVNLSDEIIITEEMKSRGSGVIHKMTGSVMTIENLAILMINLSDNTATNLCIDIA-NQ -KEINEMLSSYDFGTMKLNRKMQDYQ-AINEGKENIATPKEMNMILQMLDNKSLFNESVSN -KTLDILAINKS--TPISQPLPENIKVAGKTGGMP-GVRCETAIVXLXNX-XYILTVMTSY -GGQSEXPQN-------------- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z620_9CHLR -------------------ASIAVVHLETGASA-TVNGDRIAVPASLYKVGVLVEAFRQIE -AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV -DRVNANNQRLGLSNTRY----------YIDDRPDTTTAADMARLLSLLATGRLAGVEATG -QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN -RP-NAMKGENAIVQVARSVHAYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces ambofaciens TaxID=1889 RepID=UPI0007B424C8 --------LHAAFADAGVTGWLHAVDIDSGAQV-EHGPDQPVCTASVHKVCVLVTLHELAA -AGALDLTERVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLGRI-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLSALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ARATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000CA3A2D9 -------------------NGLVRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKEIDNYTCASDVVKCLREIYEGNLLQKSSRE -RIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNAQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SBST2-5 TaxID=2720025 RepID=UPI0014387480 -----LTRIRAAFADAGVTGRLHALDIDTGAQL-DEGADQPVCTASVHKLCLLVALHREAA -AGRLDLTERVDCPPDARTKGPTGLAVMLDSALSLRDLAYLMIAVSDNAAADLLLGRV-GL -DTVNAATDRLGLTRTRAVHTFGEMLAALDPARTNRSTPREMTRLLAAVWRDEAGTAEHCA -AMRRLLALQVW-PHRLASGFPDDVHVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ANAALPAADAVIGTAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Arachidicoccus sp. B3-10 TaxID=2545455 RepID=A0A5P2G9C5_9BACT --rKLEKKLAPLIQNFHGTSGIYVENLKTGKFV-AINADTIFPTASIVKVPILTTVYQKIL -DGKLTYNQKLIYKDSLKYGGSGFAQFFKDSTMDIATAAALMIDYSDNTTSLWLQSLVGGS -DTINAVLDKLGLKDTRDNRANREANRKIYG--WGQTTPREMATLLKDIYLKKILNPAACE -SMYRTMSHVYY-DNFALSQIPPFIQTASKQGMVDE-SRSELVMVNAPHGD-YVFYIATKN -NQQSNNEAWQLARAISKLLWHYf ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI00030573FB ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPIVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=A0A2E3R240_9BACT ---ALQARLDALADGFDGVVGVYLRHLPTGREA-TLRPDDLFPTASIVKVPILVGVFEQIE -AGTLALDTELTFRDSLRYGDSGFAQLRDSSTVYLHSAVEQMLAASDNTASLWLQGMV-TG -EAINAWLAAEGFEGTRVNSRTAGRRGDWERYGWGQTTPREMAELVRRIVDGEAVSPAADL -EMHRLLTRTHY-DDEAIAALPPSVQVASKQGAVSQ-SRSEVAYVHAPSG-PYLLMVVTKE -QAAPDNAGYDLIRAVSRLAWETf ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus pentosus TaxID=1589 RepID=UPI000B5455B7 ---QIRNDINSTVGAISGTNSVYVSPVNSKQTV--LVNDGAQRSASSIKIFIMVTAYAMAK -EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF -DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE -EMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED -GDQ--NDQIDAMNRLGSLLYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Oryzihumus leptocrescens TaxID=297536 RepID=A0A542ZJZ9_9MICO ----LAEEIRSVIRRAPGTLGVVVQD-PSGVLV-DLEGDRVVPSASTIKVLVLVAALRRVA -DGRSRMGDLLDLPAAERVGGSGPLQALGSVTLRLGELLELMVTLSDNDATNVVLDLV-GP -DGPAAVAAGLGLADTRLQRRMMDFAAR-EAGRENLTSARDLAALVAALRRGEALPPDQTR -DALELLGRQQL-RDGLPALLPPAVVCGNKTGELP-GIRHDVGLLECDGRW-AAVAVTAT- ------------------------ ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7FM18_9BACT -------------------------------SI-LIDANLRFHAASTMKLPVMIQIFRDAD -AGLLRLDESLTVHTASLVEGAFIVYALVGRNRSVRDLLERMITRSSNLATNILIERV-GA -DRAQRTARALGAWSIQVLRGVEDGA-AYRAGLNNTTTARDLGVLLQAIATGRAASGAACD -SMLAILGRQEF-NEGIPVGVPPAARVAHKTGWIGEVVYHDAAVVSPPRGGRYVLVVLTGG -IKED-SIAHNLVADLSRLVYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia fluminea TaxID=134984 RepID=A0A2N3VF10_9NOCA ----------------------HARRCDSAGEV-SVGGNDRVVIASVYKLLLLAAFLRQVD -HGLIDPAGRLTIDPSDCTPPTGLAALHDPVTLSRRDLAMSMMTVSDNAAADVLLGEV-GL -AAVGELVHELDLPDTRIIGGTADQHRAYDPSYASATTPEEMTRFLWKLWSGDILSTASTE -FARTVMSKQVW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nonomuraea fuscirosea TaxID=1291556 RepID=A0A2T0N7F7_9ACTN -------DFESLFRTAGVTGWLHAADIDTGREI-GIGSDDPLPMASMFKVPLLVALCRQAD -AGLLDPAERITVTGAGRSPPTGISAMLDEVTISLRDLAYLMIAVSDNTSADTLLARI-GQ -DTINAMLDSFGLDGTRVVQGAGESVDALDPARSNRSTPREMTRLFGLIWRDEAASAASCA -WMRGVLNAQVW-PHRLASGFPDDVAVSGKTGTLPT-LRCESGVVDYPDGGRYAVSVFTRS -FSLNQPRADAVIGTSARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga vietnamensis TaxID=2593957 RepID=UPI001177FEDE --kQLADILTPMLQSFHGQAGIYVHHLPSGKTV-AINADSVFPTASMVKIPILIGVFNKIA -KGELQYRQLLRYRDSLLYAGEDILGSFKDSEIYLDKVVMLMLTMSDNTASLWLQSLAGGG -TEINKWLESNGFVNTRVNSRTPGREAIRKVFGWGQTSPREMATLMEKIYKGEVISKAASE -RMYRNLTRNYW-DTEGVLQVPPNVRTASKNGAVDE-VRSEVIMVNAPHGD-YIYCITTKN -NAKRDNEAWQLLRKVGAAIWKHy ->[subseq from] serine hydrolase n=1 Tax=Microtetraspora fusca TaxID=1997 RepID=UPI00082A36D9 ------KQLEQIFRTAGVTGWLHAVDIDTGREV-GLGADEPVVLASVFKVPLLVAFYRQAE -RGLIDPAERVTVSAEGRPGGTGVSAMLDEVTASLRDLAYLTISVSDNASADTLLARV-GL -DEVNAVLADLGLSHTWVEHSCAELFTVLDPARTSRSTCRDMTRLLGMIWRDEAAGPASCA -AVRRLMGLQVW-PHRLASGFPDDVAVSGKTGTLPT-VRNEVGVIEYPDGGRYAIAVFTRS -IGQNQPRADAAIGTAARVAVDH- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 33-7 TaxID=2486003 RepID=UPI000F7B4ABE --------------GIKGDTSAFYYDLNNNDSA-SYGDDEPQRAASDIKVYIMAAAYQKID -DGDMSLDGRYELTSEDKVGGTGVVQNQVGDSLTYRDLIDYMITKSDNTAANIITKEIGGL -DAVNDEIDELDLRNTKMERMLMDQD-ALSEGKDNMTTAHDLAMFMRKLYHHDVVSDKYDK -QMLSILSNTSN-HSKLPANINTNVDVYNKTGEYQYGVENDAAIFKRGNKA-FVLVVMSQN -GDSD--EQKSAMGSLGKQVTQ-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=UPI0007AEB259 ---SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum EGD-AQ4 TaxID=1382301 RepID=T5JTR1_LACPN ---QIRNDISSTVGAISGTNSVYVSPVNSKQTV--LVNDGSQRSASSIKIFIMVTAYAMAK -EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIKKLGGF -DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE -AMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED -GEQN--DQIDAMNRLGSLLY--- ->[subseq from] Uncharacterized protein n=1 Tax=Chryseobacterium sp. ERMR1:04 TaxID=1705393 RepID=A0A0N0LHA8_9FLAO --kELSNNIHELISNKKLDIGISIRDHSGDEIV-SVN-NKKYKLYSVSKLFLAVYILNQVD -KGKLNLNQPILFSKKDLKPYSPLRDSIPQGTLSLKQSLKFMIKSSDNNVFDKLAVASGGL -SNLNIFIHQTFKATKDQFSIMHDYSSSQRDFESNIITPSMATEILYQLEKKEILSDHSYD -SLKNYMEHSVI-NTRIQGLIKKDTQSFHKSGTSNREACNDIGIVNLKNGKSFMIAVFISN -SKEDDATNDSLIAKITELAYT-- ->[subseq from] Uncharacterized protein n=1 Tax=Planococcus halotolerans TaxID=2233542 RepID=A0A365L268_9BACL -----EFQVKKALEHSSGKVSLAIET--KNGRI-DINSHKQMKSASTIKLAVLLEAFSQID -RDLVKPYDIIRLQPEDFTQGSGVLFHLGSVKLSFEDLLTLMIIVSDNTASNLVIRTV-GI -DRVNALLNRLGCNETVLGRQFMDIQAALD-GLDNFTSAADLVTMLKAVDSGELLSEDSRR -RVLHILKKQQL-LTNLHGRIDDEVSVASKSGSLP-GVVNDAGIFEYRGDK-VYAAVLVSD -SP-DNHSGQEVIAEIGGYIYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-475 TaxID=1463910 RepID=UPI0004C89992 -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGVLDLTEQVECSPRDRTTPTGVAAMLDGARLSLRDLAYLMMSVSDNAAADLLLHRV-GL -DAVNRTTARLGLSRTLAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus megaterium (strain DSM 319) TaxID=592022 RepID=D5DD93_BACMD -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILDLTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Bacteria TaxID=2 RepID=UPI00068C3C1C ----LRDYAENEIQDINAKVSLLVYDFDQDETLlSFHEKDRVVSASTIKTPILLTALDMVQ -SGKLSVGQMLRLPGEEILDDTEVFDRGVR-EYPLEELLTWMIINSDNTATNVLIEFL-GM -DAINACCRKLGLKATVLERKMLDWE-AIRQGRNNYTSAQDQLTVFQSLRRASILTPELCR -YALGILERQRDFSMALRYISDRDFSAAHKTGGLDY-LNHDTGIFSLPGHE-YYFGCFVTD -STDDTDENKKLIGRLSRKVYDYy ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. HB172195 TaxID=2574798 RepID=A0A5R9F7G7_9BACI ---QLESEIKTIIKELPGDYSIVIETLEG--TI-SLKGENQLPAASLIKLPIMIEAFRQSE -ANIIDLDEIVDVSTVKKVGGAGILARLSSIALTIRDLLTLMIIVSDNTATNELIDRL-ST -DKINNLCRAYNCQSTRLQRKLMDFE-ALKNGKDNLTSSKDVVKLLKGIDTGQDYSKRTRK -EMLSILSEQQF-LDKLPAFIPEEFFMANKTGELP-GVEHDAAIIKSNGK-HVYACVMFAN -LYE-NKEGKVAISEIGRAIWE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF6955A -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKDLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLKMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3D3JED1_9BACT --hNVQTKLDSIVANTPAHIAVKAIVLDTLAEY-AVHERDTMVSMSVIKLPMVCAMLEGVS -QGRFLMSQPVLVSAEDAVRHSPLRDSAGNGPTTLGRAMSAAVCLSDNIGIDVALDATGGL -SAAQSFFRNHGLDGIGAGTTYRDMGQK--GATANWMTARSMTDMLYRLHRAELFPAAERN -WVLRELSTTPTGKRRIRGLLPDSVVVAHKTGSHYARAVNDAGIISHPTGKFILITVLVND -SKLTPLQTEDVIARIARTIYD-- ->[subseq from] Beta-lactamase-like protein (Fragment) n=1 Tax=Streptomyces coelicoflavus ZG0656 TaxID=1120227 RepID=H1QTA7_9ACTN ------ARLEAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCLLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Fibrobacter sp. UWH1 TaxID=1964354 RepID=A0A254RS05_9BACT ---------------------------STQKSA-GLNESLHFPMHSVMKFPQALYVAHFLD -SAKIGIDAKVRVVKAELMQWSPMMKEMGDTAVSYAELLQWSLVQSDNNASDLLFKFCGAP -EKITRYIAKLGFKDIQIGATEAEMHTDLAKSDLNWSTPKEMSNLFEWFYKNKD-KTANLQ -FIWKTMSEVETGKDRIPAAAPAGATVVHKTGTGFKDPMNDAGIVILPNGQVQFIAVFVPE -PTAPNQ----------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CCM_MD2014 TaxID=1561022 RepID=A0A0N6ZLC7_9ACTN ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKVCVLVALHELAA -AGELDLTEQVECPPAGRTPGPTGLAAMLDPALSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPAEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -ANAVLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacillus reuszeri TaxID=54915 RepID=A0A0K9YK59_9BACL ---EIEKRLGEIIAEAEGTWGVVVEELGSGHDF-KHLPDELFIAESVIKVPIMAAVYEAAD -KGQFSVEDHLTLRKEDLVGGSGFLYRLSPGLLTIRDLITMMIIQSDNTATNMLIDLV-GE -EQIKQTMCNLGMSQSRYSRKLMIYPV--DVAENNLITAGDVASMLGKIASGTFLSQRACA -EMIAIMNKQQV-VNGLPSLLPHEWTLPCKSGWDT-GRQHDVGVLYTAGR-RITITALSQD -VQPG--AALRTLGLLGKAVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Geodermatophilus sp. DSM 44513 TaxID=1528104 RepID=A0A5S4ZKS3_9ACTN ------------------------------------------------------------- -----------------------------------RAAAEAAVRHSDDTATDVLLDLLGGP -QALDAAPETIGDDVTRVDRTEPTLDDTVPGDPRDTSTPRGLAGDLRARPRRRAGSRGPRP --PVGWLTTTTTGDARVWAGVPAGWVVGEESGAAAYGTRNDTAVVRPPRRAPIVVAVLSDR -DEPDAGHDDALVAEATRAVVA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI000BB34E82 ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -ENIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWKDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus aerius TaxID=200253 RepID=A0A2I9D6D4_9DEIO -------------HGYAGEVGVLITDLAGRGLY-ALNSGRVFPAASTIKVPLLVRALQEAQ -AGRLDLRERVTVREEDRAGGSGILHEFGPGLPTWEDLLTLMIVVSDNTATNLVIDRL-GV -ECVNGWLDGLGLGGTRLVGKLERQNEAQRRGERNRTAARDQVNVLGRLARGELLDPAHTA -LALSILSRQQL-RDILGRHVPRSYRVASKSGELP-GVHHDVGLLFTP--RPLVVAVLSEG -GL--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus actinosclerus TaxID=1768108 RepID=A0A2Z3YVT2_9DEIO -----------VAAGFAGVVGLHVTDLAGTELA-AWNAGWVFPAASTIKVPLLVLALQEAQ -AGRLDLSGRVVMQPGDRVPGAGVLHELDGGLLTWRDVLTLMIIVSDNTATNLVIGRL-GV -DAVNTWLAAGGLTGTRLVGKLEQRTEAQRRGERNATTARDQTALLRALVAGEVLDEAHTA -LALDILGRQQY-RDLIARHVPCGYCSATKSGELH-GVHHDVGVLFAP--RPLVVALLSEG -GADPRE----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia neocaledoniensis TaxID=236511 RepID=A0A317NUX9_9NOCA ----AAERIRAVFADAGCTGWLHARRCDSGDEV-CVGGSERVVIASVYKLLLFVAFCREVA -GGRIDPRARITVDPAECTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEI-GL -AAVTELAAEVGLTETRVVGGTADQHRAYDPSYASATTPEEMTRFLRLLWTGRLLPAEHTA -FARTVLGRQIW-PHRIAAAFPRDVLVAGKTGTIGV-IRNEVAVVEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=A0A3N1DNQ3_9ACTN ---AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNGTTARLGLTRTRAVYGFAEMLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=A0A1Q9SUM9_9ACTN -----PARIEAAFRNAGVTGCCHAVDIDAGRDV-GVRADEPVVLASVFKVPLLVAFHRRVA -AGTLDPTERATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADFLLDRV-GL -AAVNAAAADLGLPATFVAGSGREMLDVRPLDPTSRSTPREMTRLLSLVWRDEAAGPGECA -AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT -PVAVHPQGDAVIGTAARIAVEH- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E5NZB0_9CHLR ---------------HRGDVGISVQS-PAGEVW-SRQGDIQFPAASIAKIPIMITVYRMID -QNRLALDNEYILQNIDKSNGSGVLRHHTGIVLTLADLIFLMISISDNTATNILIRKV-GM -DLISATMKELRMSSSNLSRYFVGRL-AIEGEQENYATPNDYVRVLDSIVSGEAASASSCQ -AMLATLSLQQN-RNRIGRYVPPDFRWGSKTGTNP-GITNDVGFVTSSLGT-MCIAILCRG -LK-SEVVGEQLIADSTRAAMQ-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535XYM1_9CHLR -------------ASLQGEAGAFASDADGHALF-CENEDELFPSASVIKLPLVMTLHADAA -RSLVDLDERVGVGE--RVDGSGVLRHMRDVDLSLRDLAMLAIIVSDNTATNRLIERI-GI -ERVGERLREWGCPKTRLSRKMYDFEAATR-GHENVMTPRETVSLLLRLQRGECEDRATSD -AVLAVLEQCQD-RTMLLRYLPYGAKAPHKTGTLDE-SRNDAAIV--PGDRPIIVAAFTRK -LRDS------------------- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. MH60 TaxID=1940758 RepID=A0A2S6WMD0_9ACTN ---ATAARLDAAFADAGVTGWLHAVDIDSGTQV-GVGADQPVCTASVHKLCVLVTLHALAA -AGELDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDTAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGALWRDEACPPEYGD -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-1314 TaxID=1463882 RepID=UPI0004CBD848 -----VARIHAAFADAGVTGRLHALDIDSGDQL-DAGADQPVCTASVHKLCLLVALHERAA -RGVLDLAEQLETVPGERTAPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium paludis TaxID=1476465 RepID=A0A4R7D8U0_9SPHI --kKLTNNLKELIAGFDGEIGIYVQHFKANKTV-ELSADTVFPTASIVKVPLLVGVFDKIN -AGELLLQANYRYRLERAYGGSGLMQLFKDSAIDLSTMISLMLTYSDNVASIWCQELAGGG -QAINPLMDRLGLKDTKVNSRTAGREKIWEQYGWGQTTPREIVKLMRMIEQEELFTPRLSS -KMYRYLKNQFY-NERSLSQFPAHIATASKTGSVD-AARGEVVFVHAPSGD-FAFAVLTKN -NKTRDNAAEELTRKIANLIWNHy ->[subseq from] Beta-lactamase class A n=1 Tax=Gelidibacter sediminis TaxID=1608710 RepID=A0A4R7Q8L0_9FLAO --kTLENGLTELVKNFEGDVGIYVYNLKTQKEA-AINADTIFPTASIVKVPILIEVFNQIK -KGKLHLNDTMVYDAKRVYGGSGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELVGGG -LAINKTLADLGLEHTRVNSRTEGRTLDWETYGWGQTTPREMASLLIKMRNRTLVDDAASD -EMYRIMSNSFYTDYSL-SQIPPHVQTAAKQGMVNK-SRSELVMVNAPSGD-YVFYIATKN -NADEDNKAWELQRAISAYLWNYf ->[subseq from] serine hydrolase n=1 Tax=Dyadobacter beijingensis TaxID=365489 RepID=UPI00037FAA68 --kKLTAKLETALAGFHGQVGVYVRNLKTNRTA-AVHADSLYPTASMVKVPIMCGIFDKID -QGEVKFDQELVYRDSLKYDNGIVGSFRDSTKIALPKVVHLMISQSDNTGSLWLQAMAGGG -ATINQWLEKNGFANTRVNSRTPGRKEFQARYGWGVTSPREMAELVAMIRSGKAISPAASD -RMYRYLGMQFW-DGEAISQLPSNVKIAAKSGAVNQ-AKSEVLVVHAPHGD-YVFCIATKN -QEQKENEGYALIRKVSAIIWDHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus aurantiacus TaxID=254410 RepID=UPI0003F9AEBC ----LYSTIHKRVTELKGTYSIFIES--PRDTI-AMDENRVVPAASVIKLGIMIEAYRLID -EGQLNENDRITVRPSERVGGMGVLQHHSVESLSIGDLMTLMITQSDNTASNCLINML-GK -DQINHTIKRLGCTNTKLRRSFMDVESA-KRGVDNTTCARDMVAMLKALSNSEILTSESSK -KAIHTMKQQQL-RGKLPYRIESSFTLAHKTGELQ-GVEHDVGIMNVRGED-VYIAVLLDQ -LPN-NRLGKEAIGYIGEAIYR-- ->[subseq from] serine hydrolase n=1 Tax=Litoreibacter albidus TaxID=670155 RepID=UPI000AFF8F6E ------EAVRGIERDLGARVGLYMHDLHTDEQI-TYAAHDRFPMNSTFKLLACGALLKRVE -AGEADLTQTVSLQGMEVVSYSPAIKEHMRKGVSLNDACGMVLSVSDNTAANIVLSQIGGP -DGLTTFLRSVGDENTRLDRWEPAMNEAIRAT----------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ishikariensis TaxID=137265 RepID=A0A1H3UP96_9ACTN -----GAKLQAIVDAAPVTAGVSVRDLSGEQQI-SVAGRFRPKAASLIKLWVITELMRRID -CGQAAYTDTVLVLPTDVVGGTGELQHTFPQNVTLFRLAQYTIKYSDNTATNVLIDYLGGF -GPVNALADSMNQTQTVLARKMLA-----PAPPENFTSPDDVISLLGAVWSGNVLRQVNRD -LLLSFMLEQTL-NGKIPAALPSGVPVAHKTGELVD-VSHDVGYYLIPGT-EIAVAFLTAG -PE---ELGASTVRELARAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus soli Cha et al. 2016 TaxID=1309411 RepID=UPI0012FF4F0D --------------------GLRVTDVTGAELI-AWNAERVFPAASTIKVPLLVLALQEAQ -AGRLDLSARVTMQPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIARL-GV -DAVNAWLAAQGLTGTRLVGKLQQRNEAQRRGERNATTARDQTALLRALVAGDVLDEAHTA -LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVGLLSEG ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130E1405 ----------KKLEQLPGKISFLYENLSTGDGF-AYHEQEPMMAASVIKLFVMAAAFEKEK -KGTFHMDEMFAVKKEDRVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDII-GM -EEINKIIRELGFRQTLLQRKMYDMERA-GRGIQNYITAYETGRLLKLMYEGTLIDRQSSE -TMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEISLDLY--- ->[subseq from] Uncharacterized protein n=2 Tax=Rhodococcus TaxID=1827 RepID=C3JVC0_RHOER ---SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. D-46 TaxID=2716265 RepID=UPI0013F642CD ---SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-DYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus yeomjeoni TaxID=291403 RepID=A0A327PD85_9BACT --kNLESSIRALTDSFKGDVGIYIQNLKTGATV-EINSDTIYPTASIVKIPILLGLFDKIE -KGEISYREPLIYRDSIKYGGSGVMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQALAGGG -AEINELMATLGYENTRVNSRTLGRESIWEKYGWGQTTPKEMADILIKLNNRELISKAASE -QMYRLLSNTFY-TDYAVSGIPAGVNVASKQGMVN-ASRSEVFLVNSPQGD-YVCAIFTNN -NEDKENEAWVMTRKISNLLWNHf ->[subseq from] serine hydrolase n=1 Tax=Pedobacter oryzae TaxID=1122943 RepID=UPI0003FDDBE1 --kKLSQKLQELTQGFNGETGIFVQNLKTGKIA-VYNADTIFPTASMIKVPIMCAVFDKIE -KGELSYQQELIYKDSLLYAGEDILGSFKDGEIALSKVQMLSITTSDNTASLWLQKLT-GG -KYINQWLQTNGFTQTRINSRTEGREKDRALYGWGQTTPREMAGLLVKIRQGKAISPAASE -RMYRNMIRIYF-DQVALSQIPPYIQAASKQGAVNE-SRSEVVLVNAPHGD-YVFCVATKN -QKQANNEGYTLIRNLSALLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4VJC9_9ACTN -------DFDALFRTAGVNGWLHAVDVDSGREI-GHGSDVPLPTASMFKVPLLVEFCRQAD -AGLLDPAGRTTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR -EAVNTMLAALGLHGTRVLQSCQEFNDALDPERTNKSTPREMAELFGLIWRDEAASAESCA -WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI001412387D ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Paenibacillus sp. TCA20 TaxID=1499968 RepID=A0A069D9B0_9BACL ----------------GVRVTVSVADLSGNLGF-SIGSEERYRSASTIKLAIACALLQMVD -RGEVRLEDQAVVRDKDVVGGSGSLQLEVMPLANIGRLAKLMIAQSDNTATNVLIDMI-GF -ERVNAMLEGLGIHRTQLARKMFAPVQS--PELDNYADAQELTYLLKLVYQGEVLSEYSRR -LLLLWMSRQEV-NTKFGAVLG-DILIAYKTGEAGN-VTHDAGYFLIPGRE-LAVAVMTEV -MTEAQRIGNPVVQRIGKVIYDQ- ->[subseq from] CubicO group peptidase, beta-lactamase class C family n=2 Tax=Micrococcales bacterium KH10 TaxID=1945885 RepID=A0A239II29_9MICO ------------AASNNIRMGVSITDLADGDTI-TVGDQEPYKAASVIKLPLLAQLMDLAD -NGELSLDELVTIPESNIVGGSGTLRLREPLDISVRELMELMVQVSDNTATNVLIDRAGGF -DAINDYIAELGYETMWLGRKMI--HTAVPPLQENWLNSSEVTDFLVRLYEHDFLSAASSE -HIIDLMKGQLV-NTKFGAVVPRE-VLANKTGELGD-ASHDSGYILVEGREVALTATTAFA -APVTQAQANVYVQRAATFAYD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=8 Tax=Rhodococcus TaxID=1827 RepID=A0A1F2PWI9_RHOER ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A6A0I0V6_9BACT ----LTKKVLQAIDGFKGEVGVYVRHLKSGKTV-MIRADELFPTASMIKVPIMLTAFQKIE -EGELDYHGEQTYRDSLLYAGEDILGSFKDGEIKLSKVIMLMITTSDNTASLWCQKLVGTG -TAINEWLQAHGFSQTRVNSRTPGREADREKFGWGQTTPREMAELLVMIREGRAVSPDASE -EMYRTLTRIYWN-GEALSQIPPFIQAASKQGAVNR-SRSEVVLVNAPSGD-YVFCVITKN -QEDEDNAGYVLLRNISRLLWEYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces asterosporus TaxID=285570 RepID=A0A514JRM2_9ACTN ----ALARIRAAFSDAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCVLVTLHEQAA -AGLLDLTEQVECPPEGRTPGPTGTAAMLDAALSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLARTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus aerius TaxID=200253 RepID=UPI000CCC22E7 -------------HGYAGEVGVLITDLAGRGLY-ALNSGRVFPAASTIKVPLLVRALQEAQ -AGRLDLRERVTVREEDRAGGSGILHEFGPGLPTWEDLLTLMIVVSDNTATNLVIDRL-GV -ECVNGWLDGLGLGGTRLVGKLERQNEAQRRGERNRTAARDQVNVLGRLARGELLDPAHTA -LALSILSRQQL-RDILGRHVPRSYRVASKSGELP-GVHHDVGLLFTP--RPLVVAVLSEG -GL--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptosporangium minutum TaxID=569862 RepID=A0A243RHS5_9ACTN ------EALREAFGDADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKVPIVLEYARQAA -AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -GNLHATLRELGLERTRLIGGCAELLGILDPERTTSGTPRETTTLLSKIWRDEAGPPEACA -EVRRIMGNQVW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT -GSFRLPKADRVIGHAARVAIDH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SAI-097 TaxID=2485145 RepID=UPI000F4C7234 ---AVAARLDAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERVECPPDGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNGTTARLGLTRTRAVYGFAEMLDALDPARTNHSTPRDMTRLLGALWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Halomonas sp. MG34 TaxID=2600296 RepID=UPI001372D354 --------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQIE -SGRLHPDKLVYIEEEQFVEGSGIISYLTNSHYSYMNLIELMMIVSDNTAANVLLESL-GM -EAVNQTIEQLGAKNTVVQRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEDYISSKSRK -FMRSILAKQQF-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEE-RVYITVLSDH -LP-SNAEGQHTIAQIGKHAIDY- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=A0A1Q4K9K9_RHOER ---SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGALDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. KBW08 TaxID=2144188 RepID=A0A3N7BBW3_9NOCA ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWKDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. SBT364 TaxID=1580530 RepID=UPI00066E378A ----------------GARGFVHARDIDGDAEF-GVDPDEPVVLASVFKIAVALEYARQAA -AGELSRTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMLTMSDNAATDVLLRRV-GL -DRVHATLAGLGLRRTRLIGGCAELFAVRDPERTTSSTPRETTELLAAIWRDEAGPPEACA -EVRTIMGNQIW-PHRLAAGFGDEVIVSGKTGTLW-GVRNEAGVVEYPDGGRYAVAVFLRT -AKGRDPDADAAIGRAARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora shandongensis TaxID=418495 RepID=A0A1H3EP55_9PSEU ----VERRIREVLADAGAEGWVHAKPLNSEREI-DVGGDELVVTASVYKLPLLVALCRAFD -AGELDPRARVRIDPASCTPGPTGMSAFQDPVVSWRDLAASMIGVSDNAAADLILGEV-GL -DALADTLADLGLSRTRVVGGTADSHAAYDPSYASATTPREMTRLLELVWADAVASPEQCE -FIRRLLANQAW-QHRIRAGFPRGVRVAGKTGTIG-AVRNEVSVVEFDGETPVAVAVFTLA -ARADAPGVDAAIAECARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9MFY3_9BACT ----LDGRVRAELLKFRGKVSLFAKNLDTGLSY-GIGADDRVCTASIIKVPIMVEAFARVA -EGRAKWSDEVILTNAKKVPGAGVLQEMSDGLLTLRDAVNLMIVVSDNTATNLVLDAL-TT -DGVNERMDSLGLKQTRALRKIEDGGERAAQDPANVSTPREMVTLLERLERGGVVNPTASK -EMIDLLKRQQS-HNGIGRTLNGIVEMASKPGALDH-LRSDVGIIYAKQGR-VAMAITCDD ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Nocardia yamanashiensis TaxID=209247 RepID=UPI000A07B2BE -----AQHISAVFADAGCTGWLHARRCDSPAEI-SVDGHARVVTASVYKLALFLAFCRDID -SGRLDPTTRLTVDPTTCTPPTGLAALRDPVTLSLRDLAASMMTVSDSAAADILLGEI-GL -PAIDSLLTGLGLTETRVIGGTADMHRAYDPAYTSATTPEEMTRLLHALWTGSALSPERTE -FAKSVMRQQVW-QHRIAAGFPSNVSVAGKTGTIGI-IRNEVAVVEFPGEFPVAVAVFTRA -ARADLPAVDAAIAEVARIAVT-- ->[subseq from] Putative beta-lactamase n=1 Tax=Synechococcus sp. RS9916 TaxID=221359 RepID=Q05XQ7_9SYNE ---TLSQRWRDLAAQADLKVSAFMLVLDDGRYA-ELGADTALPAASSIKTPILLAALERLD -AGDLHWNEPLTMTKPLVGGGAGWMAKPVGTRFPTYEVATEMIRISDNTATNLMIERAGGK -QAVNIRFNTLGLSATKINNWLPDLKGT------NTTSARDLARAIALVDTGEVLSTRSRD -LFREVMSTSRT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFN-DPRSTELIRDMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SYP-A7193 TaxID=2662065 RepID=A0A5P9WMJ9_9ACTN ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAGPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. NJ-530 TaxID=2490853 RepID=A0A3G8ZUV1_9NOCA ---SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTSEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. NRRL S-836 TaxID=1519492 RepID=UPI0006AF387B --------------AAGAEGFVHAREVANGPEV-AVGADDQVVLASVFKIPVAVAYAAEVA -AGRLDETERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ -AAVDAVLAHLGLHRTRIMGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPQACA -QVRAIMAQQVW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGRAYAVAVFTRA -DSPRQPAVDAVIGRAGRLAVDH- ->[subseq from] Putative Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces aurantiacus JA 4570 TaxID=1286094 RepID=S3ZPM0_9ACTN -------RLQETFAEAGVTGRLHALDIDSGAEI-SAGADQPVVTASVHKLCVLVTLYEHAA -AGRLDLTEQVECPVDGRTSGPTGLAAMLDPVVSLRDAAYLMMAVSDNTAAELLLRRV-GL -DAVNATTARLGLTRTRALHTFSEMFAALDPARTNHSTPRDMTRLLGALWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ARATLPPADAVIGTAARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces varsoviensis TaxID=67373 RepID=UPI00099700E5 -----QRTIRGMFADAGVRGWLHVADLHRPAACvTIDPDEPVPIGSVYKAPLMVAFCRLAE -AGEIDPCRRVTLGPADRLPPTGISILRDPVTVSLRDLVVLMMTVSDNTAANAVLRLV-GT -AAVDEVCRALGMADTRVHGGVATTFAVYNPLSKASASPADMARLLRAIWTGRAASPESCA -FMREVMGRQAW-SHRLGSGFPDDVRVSGKTGTFGS-MRHEAGVIELPDGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=A0A264Z118_9BACI -------------SMYRGRVSYLFET--PEETI-EQGATNVYPSASTIKLLVAIEACRQID -SGVILAHQTIAVKQSDIVGGDGLLSVYPYSPATVKELLILMLILSDNTATNLLIKLL-GQ -ECIQGCIKDLGLKNTQLNRQMMDIQAS-AEGRDNVTTAADLLTCLKVLYRKDVLSEPSRK -LLKESLFNQRL-RDKLPSMLNEKCFILNKPGHLH-GITHDCGVLFTHHKR-CYAVVLIDG -LK-HNEYGRRLIADLGQVIS--- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. HMF3257 TaxID=2183553 RepID=A0A327NIF9_9BACT --kALERKLRAVLTNFRGNSGVYVRNLRTGKTV-SINADTLFPTASMVKIPIQCGLFDKIH -QGAIQYDQELTYKDSLHYDDGIVGSLKDGAKITLSKVVMLMETVSDNTGSLWCQALAGGG -TAINAWLETNGFHQTRVNSRTPGREANRTQYGWGQTTPREMAELLTYIRQGHAISPDASE -EMYRNLGRQYWD-NDGLSQVPPGVKVASKNGAVNQ-SRSEVVFVHAPHGE-YVYCIMTKN -QKDETNEGYTLLRSVAATVWHHf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces radiopugnans TaxID=403935 RepID=A0A1H9BAR1_9ACTN --------------ALGARVRLHARCVDCGRQT-GTGADEPVVLASVVKVPLVLEFARQAA -YGQLDPAERVLVRQADRLGGTGTAGCRDDVEMSLRDLAFLALSVSDNTAADVLFRRV-GT -DTVALLARELGLEGTRIAGSPRDLLETSDPRRTNSGTARDMTRLLALIWTDRAGPPRACA -EVRELMARQVS-WHRLAAAFPEEVAVAAKSGTLP-GVRNEIGVVSPPGGGRYAVAVFTET -ESRRRPDLDAAIGAAGRAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 41-5 TaxID=1895836 RepID=A0A1Q3K2Z8_9SPHI --qKLEKKINQAIKGFNGDIGIFVKDLKSGKTV-AINADTIFPTASIVKVPILMGITDKIM -KGQYAYDSTVAYDSSYLYRGEDILGEFKDSGIRIKKLIMLMLTTSDNTASLWLQALSGTG -TRINQILDSLGYKSTRVNSRTPGREVNRSRYGWGQTTPREIAGIIESIYRTKIFTPYYCD -IMMRSLGRNYWDEDEGISVIPPYIEVFSKNGCVNQ-TRNEVMLVNAPNR-PYILSIFTKN -NKRHDNEAWALTRKISTLLWDYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces aurantiacus TaxID=47760 RepID=UPI000D132C7D --------LQETFAEAGVTGRLHALDIDSGAEI-SAGADQPVVTASVHKLCVLVTLYEHAA -AGRLDLTEQVECPVDGRTSGPTGLAAMLDPVVSLRDAAYLMMAVSDNTAAELLLRRV-GL -DAVNATTARLGLTRTRALHTFSEMFAALDPARTNHSTPRDMTRLLGALWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ARATLPPADAVIGTAARIAVE-- ->[subseq from] Serine hydrolase n=2 Tax=Bacillus TaxID=1386 RepID=A0A2A8VWX7_BACME -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKLEELLTLMIIVSDNTATNELISLV-GF -EKINECAKDLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLKMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Beta-lactamase class A n=2 Tax=Chryseolinea serpens TaxID=947013 RepID=A0A1M5UC68_9BACT ----LTGKLQETLQGFKGVAGVYVRNLRTGKTV-TINADTLFPTASMIKIPITIGMFDRID -RGEIDYHSTLTYKDSLLYEGEDILGSFKNGEIALSKVMMLMITTSDNTASLWCQSLAGTG -TAINAWLEKNGFENTRVNSRTPGREANRTRYGWGQTTPREMAELVTRIREGKVISPRASE -RIYRNMVRIYW-DSEALSQIPPYVQAASKQGAVDQ-SRSEVVLVNAPHGD-YVFCVITKK -QETPANEGYVLLRKVSRLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI0007D8B3A8 ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-VHVPDELFIAESVIKVPIMAAVFAASE -QGHFRMDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -DQIDQTMIDLGMHQSCYSRKLMIYPLD--IAENNKITAGDVASMLGHLATGSFLSQRACK -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter immobilis TaxID=1348778 RepID=A0A3M9MYY5_9BACT --rQLTQKLLALTKDFKGDVGIYVRHLKSGKTV-AINADTLFPTASMIKVPIMVGVFDKME -RGELNPKTILRYRDSLYYAGEDIVGNFKDSSVALGKIQMLSITTSDNTASLWLQQLAGTG -TAINIWLEKNGFTHTRMNSRTPGRRSNWEKYGWGQTTPREMATLVTMIREGQAVSATASE -RMYRNLGRIYV-DDIALSQIPPNVHTASKQGAVNR-SRSEVVLVNAPHGD-YVFCIITKN -QQDENNAGYALIRAVSKTLWQHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=UPI0011E973A4 ----LKERVQAVVDSTAGHVSYVIDD-GNGQRL-GKDADVTKKAASLIKIPIMMAVFKQVE -AGILSLSDRYSIDNRNIVSGAGVIQFMESDTFTLGELLTLMIIVSDNIATNKVIDII-GW -NVVNDFCREQGLTNTKLERKMMDFKAA-DVGLENRTSALEMIECLKYLHIEDVFSDESRQ -KMLRILGGQQL-LDKLPFYMDELVGIANKTGELP-GVEHDCGIVTYKGEK-LFVAVLIDD -LV-DNSIGKRAIQEIGKVVEE-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. WMMB499 TaxID=2650775 RepID=A0A5J6UL25_9ACTN ---------------AGVTGHCHAVDVDTGRDV-GVRAGEPVVLASVFKVPLLVAFHRRVA -AGTLDPTERATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADFLLDRV-GL -AAVNAAAADLGLPGTFVAGGGREMLDVRPLDPTSRSTPREMTRLLSLIWRDEAAPPAQCA -AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT -PVAVHPQGDAVIGTAARIAVEH- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000E1A3246 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILTLTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVKKGIDNYTCASDVVKCLREIYEGNLLQKSSSE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-PYYAVVLIDG -LS-DNEQGRRLIADIGYLL---- ->[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI000762164E ----LENKIREIVIRCTGRVSVAVELP--SHSF-HINGDSTYSAASLIKIPILLEGFRQAQ -EGKISLSDRVTIPKEGRVGGAGVLVSLSDHLLTVEDLLTLMIIVSDNTASNLLIERL-GS -IAIQDLCDTLQLKQTMLRRKLMDFEA-VEQGLNNYTSALDIISCLKVLDIGTEYSPTSRK -KMLHILHQQQF-DTKLPSRMDRGVYIANKTGELP-GVEHDSAIIKFREKT-AYIAVLIDE -LGQN-EPGKDTIAQIGKLMS--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 203-3 TaxID=2559918 RepID=UPI0010F7BD68 --------------------AV-AIQTTTGQTY--YWHNRQQKAASVIKLFILATVYQQVV -DKTLRLDTTYTLKARDKVGGTGNLQAAVGTPVTYRALVKAMMTVSDNTATNILIRAVGGR -TVVNREIARLGATKTRLNRLMMDQ-TALAAGRDNVTSVGDLSRVLMRLWHHRLISPAADT -AMLNLMAANTN-HQKLPRLVSSQLKVYNKTGEFDYGVENDAAILAKG-RRAIVVVALSQG -GT--LAQQLPAMNQLGHQVT--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-244 TaxID=1463897 RepID=UPI0004C063BB ------RRIAAAFAEAGVSGRLHAVDIDSGTEI-DAGADQPVVTASVHKLCLLVALHQHAA -AGRLDLTEQVECPPADRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGATARIAVD-- ->[subseq from] Amidohydro_3 domain-containing protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7VHR0_9BACT -------SVQALKRKHKERLGIALYDSETRVQW-SYNGDAFFHAASTMKLAVLVGVFRQVF -RKELGLETPVRVRNRSLVGGLPFSVARLGKTMNVKDLAYRMITTSSNFATNLLIDLV-TV -GVIHKALDELRVEGIEVLRGVDDQK-AFAAGKNNMVTADGLLKLLRLISDGRVYSPEISG -QLLEILLDQRV-KRGIPAGLPGGARVAHKTGHIST-VHHDAGIVYIGQRRPYAVVILTQS -PA--GAGGDAAVADASRQIYN-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XGD1_9CHLR ------------ATDLDGSAGLIVLDAGGTVLY-ERAADESYAAASVIKIPILMTVYADAA -EGRLSLDERIGVGE--HMPGTGVLGHVRGVALTIRDHATLMTIVSDNTSTNRLMERV-SV -ERIAERMREWGCVRTELRRKMFDFEAA-NRGLDNVASPREVAGLLLRLVRGELVDRATSD -AVLAVLEATQD-DALIRRYLPARTKVAHKTGSLDK-VRNDAAVIWAE--RPVVTVGFVNG -V---------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Desulfocucumis palustris TaxID=1898651 RepID=A0A2L2XGC0_9FIRM --qGLQNRLEQMLGREKGTYGVLVMDIQSGRVC-ALNPLEPFHAASTFKLPMNIYLFKKIA -SGETDPGQKLVYRESHYEGGTGKLQYSPGTSYTIETLSQYSIIYSDNVATNVLLSFL-GK -KNVKDFMRQSGGLVV--------------DDSKNLTCPRDMALYMRELLEFAGQSPEQAN -RLIDYLENTVF-NERIPALLPKSVKIAHKIGNWPTATYNDVGYVRHPVN-PYIISIFSKN -TP-GAGRAYDVISRISKAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus testis TaxID=1622072 RepID=UPI00067E7379 --eQLKAELSKALAGFQGSIAYAIYD--GDGCI-AMNAGQRMKAASTIKLPLLLMAFRLYE -QGRLDIHREIPFTDLDIVPGSGVLQSMKQRSIRLEDALSLMITVSDNTATNLVIDAI-GL -DRCKDGFRDIGLKTASLQRKMMDYEGR-EAGKENWISAEDLIVSLKRIQNEGSFSEESRK -AMREMLINQQF-RDKLPYLIDENIAVANKTGEIE-GVENDCAIFFYKNHV-LYAAVLCGN -LKK-EGEGQRIIRHIGDK----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu 2975 TaxID=2676871 RepID=UPI00135A2782 -----EERLRAVFAGAGAEGVLHAVDIDGPGEA-GYCADEPVVVASVFKVLLVLEFARQSA -AGQLDPRERVRVTSERRLGGWGTGGCLDDVELSLRDLAHFAMAVSDNTAADLLLERV-GP -DTVAMLAKELGLVNTRIVGGPRQVLEVYDPARTNASTPREMTRLLRMVWRDEAGPPEACA -RVRDLMCRQVF-RHRLAAGFGDGVRVAAKTGTLP-GLHNEVGVAEFPDGGRYAVAVFART -PGANHTETDVAIGAAARTAVD-- ->[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora rectivirgula TaxID=28042 RepID=UPI0003FD27FD -------------SRFPGRVCLAAWHLEEREPV-LVNAETVVHAASTIKTLVMITALQQVQ -AGRLALDAEVPLPAE-RPGGAGVLAELTSVHLSLADLLRLMIVISDNTAANAVIDVV-GF -PAIRRCAEQLGCTATRVERRLMEVSA--PG--RIETTALDQARVFDALATGRALTTELTG -FALDVLRRQQV-RDRLPALLPREAGCWHKTGEIS-GVRHDVGLIGGS-RPQAVVAVLVDQ -LTDERSTADELIARIGRAAFD-- ->[subseq from] zinc_ribbon_2 domain-containing protein n=2 Tax=Enterococcus pallens TaxID=160454 RepID=R2QQI0_9ENTE ----------------DGNFSVLLAPIEDGPTF-TMEEKNMRRAASVIKLFIMAAVYEQVD -QKRLALNQEYTLLSQDIVGGTGVLQDYPIGSLTINQLLAHMMVDSDNTAGNILVEQLGGL -SELNNYLREQNFSGTVMNRLFLDTE-ALEAGIDNYTSAEDVARLLQNVYQQKQVSPVHDL -AMLELLNQNKN-HRKLPAQIGPEVNIYNKTGEYDYGIENDACIFEKDGN-AYVLVVLSED -GNSS--EQLVAMNRLGKEFYETf ->[subseq from] Serine hydrolase n=1 Tax=Bryobacterales bacterium TaxID=2026791 RepID=A0A3D1B169_9BACT --qDLDRRINSEVDNFNGAVSLFAKNLNTGGTF-EIAGQRRVRTASTIKLAVMAAAFTEVS -RGHAAWTDRSTITEAGKISGSGVLMEFSEGVLPLIDLLRLMIVVSDNTATNLVLDHI-AP -DVVNAEMQQLGLIQTRCLRKVLNNHDENKAFGLGVSTPREMVTLMEKLYRGEVVSPRASA -EMLAILKRQQH-HSGIGRTLR-ETTIASKSGALDH-LRSDVAIVYAKGG-PIAMAITCDD -IPE-------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces calvus TaxID=67282 RepID=UPI0011520B6A -----LARIHAAFSDAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCVLVTLHEQAA -AGLLDLTEQVECPPEGRTPGPTGTAAMLDAALSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLARTRAVHSFGDMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Rufibacter ruber TaxID=1783499 RepID=UPI00082CA865 --kKLTQKLEALANGFQGDVGIYVRHLKTGKTV-AINADTLFPTASMIKIPIMVGMFDKME -RGEIDPKTVLRYRDSLYYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQQLAGGG -EAINAWLEKNGFQHTRMNSRTPGRRPNWVNYGWGQTTPREMATLVTMIRDGKVVSPAASE -RMYRNLGRIYY-DREALSQIPPYVHTASKSGAVNQ-SKSEVVLVNAPHGD-YVFCIITKN -QQQDDNAGYVLIRKVSNTIWNHf ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus gobiensis TaxID=1441095 RepID=A0A0M4FMQ0_9BACI --------------------SLCIC--TDDGEI-NINDNQRMAAASVIKLPILLEGFRQSN -VNLLNLETKIEVTDQDRVGGSGVLKSFRGVELSVRNLMALMITVSDNTASNLLIDLI-GM -KNIQSFVNSVGCSNSFLRRHFMDTQA-MKAGIENETTARDMVGCLKLIAEKNIFTELNRE -EMLSMLSGQQF-HKLINQPVGPNIELYNKTGDLP-GIDHDVAILKHKER--LVYIAMLTK -GWKDRETGLKIIKRIGQLMMR-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces radiopugnans TaxID=403935 RepID=UPI000B883120 ---------------LGARVRLHARCVDCGRQT-GTGADEPVVLASVVKVPLVLEFARQAA -YGQLDPAERVLVRQADRLGGTGTAGCRDDVEMSLRDLAFLALSVSDNTAADVLFRRV-GT -DTVALLARELGLEGTRIAGSPRDLLETSDPRRTNSGTARDMTRLLALIWTDRAGPPRACA -EVRELMARQVS-WHRLAAAFPEEVAVAAKSGTLP-GVRNEIGVVSPPGGGRYAVAVFTET -ESRRRPDLDAAIGAAGRAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=A0A1V2TEU3_9NOCA --------IRDVFADAGCTGWLHARRCDSADEV-SVGGGERVVTASVYKLALFIAFCRCVD -AGLIDPAEPLTVRPAECTPPTGIATLHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -RAIEDLLTGLGLTQTRIVGGTADIHRAYDPAYTSATTPEEMTRLLREVWSGAVLSPGQTE -FVRTVMRNQIW-PHRIASAFPRGVSVAGKTGTVGI-IRNEVAVVEFPEEYPVAVAVFTRA -ARADLPIVDAAIAETARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. dk17 TaxID=2599295 RepID=A0A563U7U8_9SPHI ---KLTTQLQKAVSGFNGQVGVYVQNLKTGKVA-AINADTLFPTASMIKVSILAGVMDKIE -KGELQYNQKLKYRDSLLYAGEDILGSFKDGDIYLSKVAMLMITMSDNTASLWLQKLA-DG -KNINNWLEQNGFKYMRINSRVEGREAMRPIYGWGVTTPREMCKLFTMIHDGTAVSPAASE -RMYRTMSHIYW-DQNALAQIPPYIQTISKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN -NKTADNEASTLIRKISALLWHYy ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacillus sp. AG162 TaxID=2572910 RepID=A0A542Q6C2_9BACL ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEDLVGGSGILYALSPGLLAIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIEQTMIDLGMRQSYYSRKLMIYP--IDITENNKITAGDIASMLGQIATGSYLSQRACK -EMIAIMKKQQV-RNGLPSQLPNQWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Serine hydrolase n=2 Tax=Deinococcus sp. S9 TaxID=2545754 RepID=A0A4R5G8N3_9DEIO --------------GYVGEMGVLITDLAGRELY-ALNPNRVFPAASTIKVPLLLLALSEAQ -AGRLDLSGRVTLRAEDRVPGAGVLHELMPGLPTWQDLLTLMIVVSDNTATNLVIERL-GL -DRVNDWLDERGLSGTRLVGPLERQNAAQRRGERNRTTARDQVALLGALVRGELLDRRHTG -LALSILERQQL-REILGRHVPCDYRVASKSGELR-GIHHDVGVLFTP--RPLIAAVLSQG -GLDPR------------------ ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YAP9_9CHLR -------------------ASIAVVHLETGASA-TVNGDRIAVPASLYKVGVLVEAFRQIE -AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV -DRVNANNQRLGLSNTRYYI----------DNRPDTTTAADMARLLSLLATGRLAGVEATG -QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN -RP-NAMKGENAIVQVARSVHAYf ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2E7BNN8_9BACT --dKFQQDLEALVEDFNGVAGLHIMDLTDRTRF-AISDGLVFPQASAIKIPILLELFRRAD -TEPGLLAKRVDLTDAVRTAGSGVLQILTDGGLSLEDYAIYMIVYSDNTATNVLIDEL-GM -EEINALSTSLGARRTRLQRKMIRPEESVLG-NENLSTPRDAALIMEKIATCDLLSQASCK -RVRDILELYKGG--PIRAPIPRSVPIAFKPGGIV-GVATVWGLVNLPDR-PYIVAVMSNY -GG----NGSAMIEAVSAVAYSYf ->[subseq from] Beta-lactamase class A n=1 Tax=Halorubrum cibi TaxID=413815 RepID=A0A521BWE8_9EURY ---DLAEAIDAIAERFDGHLGVFLGVPRESNAFhRRNADETFVAASTIKLPILYALYEEYD -GRLDDLAEPRSIAPENRVGGSGMFHLLEDPTPSLEDLARAMIAISDNAATNQLIDEV-GA -ERVEAAASRLGMNDTRLRRKMMSTLEQPEGEPANATTPADCARFFADLIHETTLSPAAYD -RLRVPLDEQKD-TSLFARYLPYGTPIAHKTGGLPT-AALDAGIVRADDGPALVFAAFATR -AE-NGGDAGDAVAAVGDAAFERf ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=A0A4R4P0N4_9ACTN --------IEAEFRAAGVTGFLHVADMDTGREV-AVRAGEPVVLASVFKVPLLVAFHRRAA -AGLLDPAEQVTLAPGDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVLDRV-GR -DAVNAAAADLGLRATVVEVNGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPDHCA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-VRNEVGAVEYPDGARYAVAVFTRS -TLAVLPRADAVIGTAARLAVE-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Bacteroides ovatus TaxID=28116 RepID=A0A641W8R3_BACOV ------------------------------------------------------------- --------------------WSPLRERFPQGGFSLKGLLGVTVQESDNNTCDLLFGLIGGP -QAVQKDLKEWGIDGINVRFTEEEIHRNHDLQYVNSSRPSAMNSLLRAFDEGKILARGTQN -FLWGIMAGCSTGPERLKGQLPRDYVVAHKTGSGFVTARNDVGIIVLPNGRKMAVSVFIRD -SKDSESACDRVIASMARWLCMEw ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. HBUAS56010 TaxID=2571127 RepID=UPI00117774B6 ----------KRLEQLPGKIGFYYENLNTEDVI-FYKDQEPFLAASVIKLFIMAVAFEQLE -RGDYNCKMLFSIKQKDCVPCGALTYLHEGIEVTVMDLITLMIIFSDNTATNVLIEHM-GI -EEINTAIKRFGFEKTVLRRKMFDLEKA-RNGIENYITVGEVGKLLKIMYAGTLISKQASE -KMLSIMKNQQL-TGKIPFYLKHMPEIAHKTGEDM-GISHDVGIIYGKN--PF-IVCFCGN -ET-DTPRFERVMADISLELYK-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI0013C1F072 ---ATAARLDAAFADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAGPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga marina TaxID=1196024 RepID=A0A271J886_9BACT --------------------AVAVRDLETGEAA-TVDGDRPFHAASTMKVAVLAALLAAVA -DERHHLDDRLHVRNRFRSAGSPFRFAKRGRTMPLGTLAEHMIQTSSNLATNLLVDLL-GV -EAIREATARWGGAGVEVVRGVED-EAAYEAGIVNTATAYGLVGLFVGLEEGAGLPDEVRQ -FGLDVLFGQEF-ASGIPAGVPEGSRFAHKTGSIST-VQHDAGLVYLPDRRPYAVAILTEW -EADATNGRRETVASLSRAVYDH- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A3D2FNG6_9BACT --eKLETDILELLQGFNGDVGVYVRHLPSNTEV-GVNENEIFPTASMIKVPILVKIFDKIE -GGALTMDSVVIYKKASINYGDDALARFNDGEITISKLLTYMITFSDNHASLWLQDMAGGG -VTINGWLKNKGFIHTRVNSRTPDREAEYEIYGWGQTTPREMAELLVLIREGRAVSPAASN -DMYRHLTRIYW-DDEALSQIPPTVQVASKQGAVSQ-SRSEVVLVNAPSGD-YVFCIITKN -QTDTDNEGFILIRNISKLLWQHf ->[subseq from] serine hydrolase n=1 Tax=Bryobacterales bacterium KBS 96 TaxID=639034 RepID=UPI00037AA8B9 ---KLSQRIAYKIAGFPGKVSLFAENLQTGASY-GLLANEPVRTASTIKLAVMIECFAETG -EGKLKWTEPLAVSAENKVSGSGVLTEFSDGVLPVRDVMHLMIVVSDNTAANMLLDRV-TG -NAVNARMAGLGLRQTRIMRKILGDAGAKPENRKGRSSPREMVEILEKLYHGDLISQNASA -EMLAVMKRQQD-HSGIGRDLN-DVTIASKSGALDR-LRSDVGIVYSERG-PIAMAITVDD -IPTADNPGSLLISAVSDI----- ->[subseq from] Uncharacterized protein n=1 Tax=Oceanobacillus iheyensis TaxID=182710 RepID=A0A2P1WPA6_9BACI --------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQIE -SGRLHPDKLVYIEEEQFVGGSGIISYLTNSHYSYMNLIELMMIVSDNTAANVLLESL-GM -EAVNQTIEQLGAKNTVVQRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEDYISSKSRK -FMRSILAKQQF-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEE-RVYITVLSDH -LP-SNAEGQHTIAQIGKHAIDY- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A2W6Z3B2_9CYAN ---ALSQRWKALAAQKDLKVGGYLLVLDDGRFA-QLDPDVPLPAASAIKTPILLAGLEDLD -AGKLRWNDPLPLTKEVIGGGAGWMASRPIGTFPFSEAATEMIRVSDNTATNLLIRRLGGK -LALNARFQALGLDATVLNNWLPDLEGT------NTTSPRDLARSIALVDTGEKLSPRGRD -HFRSILATSRT-NTLLPLGLLKGIAVLNKTGDIGI-AYADAGLIELPNGQRAVAAFMVKG -PFND-PRSAELIRAMAAAAS--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=A0A1Q5M873_9ACTN -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVPTASVHKLCVLVTLHEQAA -AGLLDLTEQVECPPAGRTTPTGVAAMLDAVRMSLRDLAFLMMTVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARTAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7UAW0_9BACT -------SIQAVKRKHKERLGIALYDSETRMQW-SYNGDAFFHAASTMKLAVLVGVFRQVF -RKELELGAPVHVRNRDLDRASPEVAGRLGKTMSVKDLAYQMITTSSNLATNLLIDLV-TI -GVIQKALDELRVQGIEVLRGVDDEK-AFAAGKNNMVTAHGLLRLLRLISDGRVYSPEISA -ELLEILLDQRH-KSGIPAGLPGGAHVAHKTGNIST-VHHDAGIVYIGKRRPYAAVILTQS -AA--GVGSNTAVAEVSRQIYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptosporangium canum TaxID=324952 RepID=A0A1I4DBK2_9ACTN ------EALREAFGDADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKVPIVLEYARQAA -AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -GNLHATLRELGLERTRLIGGCAELLGVMDPERTTSGTPREITTLLSKIWRDEAGPPEACA -EVRRIMGSQIW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT -GSLRLPKADRVIGHAARVAIDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga skermanii TaxID=331697 RepID=A0A327QMQ9_9BACT --rKLTEQLQPLLRSFQGRAGIYVENLSTGKIV-QINADTVFPTASMVKIPIMVGIFQKIA -HDSLTYHQALVYRDSLLYEGEDILGSFKDSEIQLSKVMMLMLTMSDNTASLWLQSLAGGG -QSINNWLGEHGYTYTRVNSRTPGRQANRELYGWGQTTPREMATLMKSIYQGKVINKTASE -RMYRNLTRNFW-DTEGAVMVPANVRTATKNGMVD-ASRSEVILVNAPHGD-YVYCLQTKN -NTERNNEAWVLMRQVAALLWKYy ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus sp. Leaf182 TaxID=1736290 RepID=UPI0006FFF24F ---ELEKRLSTIIGQAEGTWGVVVEEQGKGIRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEDLVGGSGILHALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIDQTMIDLGMRQSCYSRKLMIYP--LDVTENNTITAGNVASMLGHLATGSYLSERACK -EMIAIMKKQQV-RNGLPSQLPPAWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKE -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium canum TaxID=324952 RepID=UPI000AC9A41A ------EALREAFGDADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKVPIVLEYARQAA -AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -GNLHATLRELGLERTRLIGGCAELLGVMDPERTTSGTPREITTLLSKIWRDEAGPPEACA -EVRRIMGSQIW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT -GSLRLPKADRVIGHAARVAIDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter ruber TaxID=990371 RepID=A0A1G9TGI2_9SPHI --kRLTKELHKLVKDFKGDAGIYVQNLRTGRVA-AINADTIFPTASMIKVPIMCGVFDKIE -KKELSYHQSLTYRDSLLYAGEDILGSFKDGEIQLSKVQMLSITTSDNTASLWLQKLV-GS -EHINKWLAENGFEHTRLNSRTAGRQAYQKLYGWGQTTPREMALLVKKIREGQAVSPAASE -RMYRNMIRIYW-DAEALSEIPPYIQAASKQGAVNR-ARSEVVLVNAPHGD-YVFCIATKN -QETPDNEGYRLIRNLSKLLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=A0A1Y0CPI7_9BACI ----LKERVQAVVDSTAGHVSYVIED-GGGQRL-DKDAYVTKKAASLIKIPIMMAAFKQVE -AGILSLSDRYSIDTRNIVSGAGVIQFMDGDTFTLGELLTLMIIVSDNTATNKVIDII-GW -NGVNDFCREQGLTNTKLERKMMDFKAT-AAGIENRTSALEMIECLKYLHIEDVFSDESRQ -KMLRILGGQQL-LDKLPFYMDELVGIANKTGELP-GVEHDCGIVTYKGEK-LFVAVLIDD -LV-DNSIGKRAIQEIGKVVEE-- ->[subseq from] Beta-lactamase n=1 Tax=Saccharopolyspora rectivirgula TaxID=28042 RepID=A0A073B8H8_9PSEU -------------SRFPGRVCLAAWHLEEREPV-LVNAETVVHAASTIKTLVMITALQQVQ -AGRLALDAEVPLPAE-RPGGAGVLAELTSVHLSLADLLRLMIVISDNTAANAVIDVV-GF -PAIRRCAEQLGCTATRVERRLMEVSA--PG--RIETTALDQARVFDALATGRALTTELTG -FALDVLRRQQV-RDRLPALLPREAGCWHKTGEIS-GVRHDVGLIGGS-RPQAVVAVLVDQ -LTDERSTADELIARIGRAAFD-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=UPI0007E5A6E3 ----AQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGT-18 TaxID=2493087 RepID=UPI000F629538 ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA -LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPGGRDGATVVVACAE -HFGELEQAEQAFQALGRALA--- ->[subseq from] serine hydrolase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI0008311EE1 ------KQLEQIFRTAGVTGWLHAVDIDTGREV-GLGADEPVVLASVFKVPLLVAFYRQAE -RGLIDPAERVTVSPEGRPGGTGVSAMLDEVTASLRDLAYLTISVSDNASADTLLARV-GL -GEVNATLADLGLPHTWVEHSCADLFTVLDPARTSRSTCRDMTRLLGMIWRDEAAGPASCA -AVRRLMGLQVW-PHRLASGFPDDVAVSGKTGTLPT-VRNEVGVIEYPDGGRYAIAVFTRS -IGQNQPRADAAIGTAARVAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED19 TaxID=1986596 RepID=A0A1Z8N772_9SYNE --kALSTKLAQLAAQKDLKIGAFALVLDDGSYA-QFNPDLVLPAASSIKTPILLVTLEALD -AGKLKLDELLSLNKTIVGGGSGWMGGQPGSQFTVLEVATEMIRVSDNTATNLLIQRLGGK -TALNARFQELGLEGTVINNWLPDLEGT------NTTTARDQARSIALVETAEVLSPRSRD -LFRQTLGTSRT-DTLIPRGWLQGVRAYNKTGDIGI-AYVDSALIELPDGRRAVASYMVRG -PFN-SPRSTNMIRALSGATAAAf ->[subseq from] serine hydrolase n=1 Tax=Lacrimispora amygdalina TaxID=253257 RepID=UPI000BE322CB ------EVITRKLNQLSGKISFLYENLETGEHI-GYREDQPQMAASVIKLFVMAFAFHQFD -TGKLMKDFSLSIHKKDCVPCGALTYLHEEIRVTALDLVTLMIIFSDNTATNVLIDLF-GI -EEINQYIASLGFERTCLNRKMFDLEKS-RQGIQNYITASEAGRLLKMMHRGELVSDTASR -QMISILKNQQL-RSKIPFYLQEKPEIAHKTGEDR-GITHDVGIVYGK--VPLLLCFCGNE -T--DTPAFERIMGELS------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CB02400 TaxID=1703944 RepID=UPI000A849B81 -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVPTASVHKLCVLVTLHEQAA -AGLLDLTEQVECPPAGRTTPTGVAAMLDAVRMSLRDLAFLMMTVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARTAVD-- ->[subseq from] Beta-lactamase n=2 Tax=Streptomyces sp. AcH 505 TaxID=352211 RepID=A0A0C2ACV5_9ACTN ---DAQRAIRGMFADAGVRGWLHVAELRRPTACvTVDPDEPVPVGSVYKLPLMAAFCRLAE -TGGLDPRQPVTLGADDRMPGSTGLSILRDPIVSLRDLVVLMMSVSDNTAANAVLRHV-GP -AAVDALCQELGLPDTHILGGVATTFEVYNPLSKASSTPSDMARLLRAIWTDDAASAESCA -WMRETMGRQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGAVYTAVVFTQA -ARADLPRADAVIGTAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. K2S05-167 TaxID=2320857 RepID=A0A418V7K6_9DEIO -------------RGFAGEVGLLVASLEGEVLY-RHAEDRVFPAASTIKVPLLIAALQRAQ -AGDLELNGRVMMQDTDRVPGAGVLHELAGGLLTWRDVLTLMIVVSDNTATNLVIEQL-GL -DPSNAWLQARGLRETRLVGKEHLRNEAQRRGERNVTSARDQAALLLGLVRGDLLDGVHTR -LALEILKRQQL-RDIIGRRVPRDYAVASKSGELS-GVHHDVGVLYTP--RPLVVALLSQG -GQDPRE----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-192 TaxID=1119093 RepID=A0A542TVL8_9ACTN -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGVLDLTEQVECSPRDRTSPTGVAAMLDGARLSLRDLAYLMMSVSDNAAADLLLNRV-GL -DAVNRTTARLGLARTLAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia paucivorans TaxID=114259 RepID=UPI000308390F ----VEDRIRAVFADAGCTGWLHARRCDSAAEI-SIAGYDRVVTASTYKLMVLVAFCHAVD -LGRIDPLAPITVVPSECTPPTGISALHDPVTMSRRDLVTSMMTVSDNAAADILLDEV-GP -GAVEELLDRVGLTRTRIIGGTADIQRAYDPAFTSSSTPEEMTRLLQAIWTGTVVSVEQTE -FIRTVMRKQVW-PHRIASAFPRGVTVAGKTGTIGV-IRNEVAVVEFPGEYPVAVGVFTRA -ARADLPVVDAAIAEAAWIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Solimonas sp. K1W22B-7 TaxID=2303331 RepID=A0A346N395_9GAMM ----------ALFQAAGVDGWLHALDLADGREI-GYHADEPVVAASVFKIPVMVELCRQAD -AGQIDLSEPVSVPLAGRAPPTGLSMGLDATTLSWRDLALSMIVVSDNAATDVLCLRL-GI -DRINATMAGLGLAGTRLEGDCRFLFAALQPLQTNRTTPREASRLLAAIWRNEAASGDGCA -LMRRILGAQVW-PHRLASGFPDGIRTAGKTGTLVK-VRNEAGVVSYPDGRHYAVSVFTRS -HDAKHPAQDRAIGQAARRAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium RIFOXYA12_FULL_61_11 TaxID=1797896 RepID=A0A1F9MBW3_9DELT ---ELQRRTLPIVRSFQGELGLYVRVIGKRGVY-DLHAQSPFYLASTVKVPLLVALLHEAR -EGNLDLRQRITLSREHYRDGGHHLMALPEGTLSLEEVASYMVEKSDNAATDLLFDRL-GV -ERVNHLVRELGFAELGPLLPMLEVRRAFYSSGYNTSTLEAFAGFLERLYLRQVLGDPYDG -KVLNLMGRCETGANRLRKHFPPQATFAHKTGTQHQ-LVVDLGLAELPCVQGVLIAAYARK -FK-TRTGGDAALASLGRATLQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Veillonellaceae bacterium DNF00751 TaxID=1384082 RepID=A0A134CND5_9FIRM -hdRTLQRIQQQLQSQDGIYAVYFQPCKAGALP-VIYNDHTMRSASMIKVFILSAAMEQIK -QGKMSFDQTITLQEADKVGGAGSLCGYPDGSVDVRTLLKLMITQSDNTATNLMIDLV-GM -DAINHYMQQHGYTETRLEWKMMA-QTAPGETRKNRTSVRDLGTWFRRVYEKKCVDPALDQ -YMIDLLLGQTD-TECFPTALP-EAKIAHKTGEVTN-LYDDGGIIFTSHGD-YILCIMTDQ -IAR--YDGIETMKKIARMLVE-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. WB02_MRS01 TaxID=2605777 RepID=UPI0012B1F8BC -------EIIEKLEQLPGRISFLYENLKTGDGF-AYHEQEPMMAASVIKLFIMAAAFEKSK -KGTFQMDELFAVKKEDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNVLIDIL-GM -EEINETIQGLGFERTILQRKMYDMVRS-AQGIQNYITAYETGRLLKMMYDGTLIDRQSSD -TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEIS------- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. 14171R-50 TaxID=2703789 RepID=A0A6B9YWW2_9SPHI --kKLTAQLQTAVKGFNGQVGIYVQNLKTGKSA-AINADTLFPTASMIKVSILSGLMDKIE -KGEMQYNQKLVYRDSLLYPGEDILGSFKDKDIQLSKVALLMITMSDNTASTWLQKLV-GG -DYINTWLEQNGFKVMRVNSRIPARRAIWEIYGWGVTTPLEMCRLFTMIRTGKVVSPAASE -RMYRMLNRIYW-DDKALSQVPPYVQTISKQGAVD-ASKSETVLVNAPHGD-YVFSVITKN -NKDQDNEADLLIKKVSALLWHYf ->[subseq from] Uncharacterized protein n=1 Tax=Pontibacillus chungwhensis BH030062 TaxID=1385513 RepID=A0A0A2USL8_9BACI --nKIDSKVEHLISQKNAPYSILIRN--NNRTIiSKNENIPFRAASVIKVPIMMEAFRKHR -EGKLNLDKLHTIKPSEEVAGAGVIHYLSGQQYSLRQLIELMIIVSDNTASNLVLKAV-GM -ESVNSLMYQLGCENSILERFFMDSA-AVEKGFENRTTAGDMITCLQAINEHPLFSKEDQI -AMKKILHNQQCKDMLGSFTSTEEIEIFHKTGELE-GAQHDVGFFEYKGQ-SVYAAVLTDD -LTKN-QEGREWIASIGQLIAE-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. Root136 TaxID=1736458 RepID=A0A0Q7NGL2_9NOCA ----------------------------SAGEV-SVGGHDRVVVASVYKLLLLAAFLRQVD -HGLIDPAGRLTIDPADCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -AAVGELLQELDLTDTRIVGGTADQHLAYDPSYASATTPEEMTRFLWKLWSGDIVSTASTE -FARTAMSKQIW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Rufibacter tibetensis TaxID=512763 RepID=A0A0P0C832_9BACT --qKLTRKLQDLTKSFQGEVGIYVRHLKTGKMV-AINADTLFPTASMIKVPIMVGVFDKIE -KGELNPKAILRYRDSLYYAGEDIVGNFKDSSVALSKIQMLSITTSDNTGSLWLQHLTGTG -TAINAWLEQNGFEHTRMNSRTPGRRANWQKYGWGQTTPREMASLVTMIREGKAVSPAASE -RMYRNLGRIYV-DDVALSQIPPTVQTASKQGAVDQ-SRSEVVLVNAPHGD-YVFCIITKN -QKDENNAGYALIRAVSSTLWNHf ->[subseq from] serine hydrolase n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=UPI0006A945E9 ----LREDLMKVVHECPGSVSFTILS--HDESL-SWEENRRKSSASLIKLPIMMTAFEQIQ -TGSLNGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLKLMITVSDNTATNRLIELI-GK -DSINRFCLTWNLKRTFLNRKMMDFRS-LEMGQDNWTSSMDVVSCLKGINEGPF-KEASKR -KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDG -LQAP-EDGRRAISRIGKLVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A431MC52_9SPHI --kKLTRQIAQIMNGFHGQVGIYVHDLHQNKVV-QILADTVFPTASMVKIPIMIMLMDKMK -SGELAYHQPFTYSDSLVYPGVDMLASFKSNEIELSKLMLLMLSLSDNTASLWLQQIAGGG -TRINALMDSLGYQQTRVNSRTAGREANRNAYGWGQTTPYEMANIMERMVAGHLLGQPYDA -KMLRLLGRNYW-DEEAISQIPADVFVASKNGAVD-ASRSEVLFVNGKKA-SYIFCICTNH -NSESNNEAWELTRKISKLLWDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Fretibacterium fastidiosum TaxID=651822 RepID=D4M750_9BACT --------IYERIAKLDAFTGLYVEAIESGEVV-EINPNRALCSASIIKLPILALALKDVG -EGRLDWKKTYQIASANRVGGTGVLRELDEIRASLEKLAFLMIALSDNIAANQVIDLI-SM -DRITPFCRSLGYTNTRCERKQLDMQ-AIREGRNNYTSAGDAGRMLSAVARGELVNPVASR -LIHSIMSRQMC-RNKLPAKIPAIVLAANKTGELLD-VQHDAGIFTLPDGRRYVIAMLTGE -VK-DANDAVNAIADVSRIVYDA- ->[subseq from] serine hydrolase n=1 Tax=Heliorestis acidaminivorans TaxID=553427 RepID=UPI00124C8315 --nQLEEKIKSQLYRFGGTYGLYVEDLTTGNKL-EINADKSFPAASVIKVPLVLFLYSLAL -DDRVDLDEKIVFEEKDREAGTGILKTAVGSSYTLRQLAQYTIEYSDNSATNMIMRRV-GR -ENFYFFLRLMGAEIIPLGPG-----------KGNIMCARDAGLYLKGVMVLRELHPEYGQ -EILQHLLNSKF-EDRIPAGVPQGVQVANKIGTQVN-VINDAAIVLLEGR-PYILAVLTSH -IHE--QEAVGAIAQISRLIFEH- ->[subseq from] Beta-lactamase class A n=2 Tax=Algoriphagus locisalis TaxID=305507 RepID=A0A1I6XKT4_9BACT ---DLTSEINDLLKTFNGDVGIYVEHLPSGNKV-EINADTIFPTASIVKIAILLGVFDKIE -KGELHYREPLVYRDSIKYGGSGIMQYFQDSTTDLSTLLALMLSYSDNTTSLWNQALAGGG -ADINVLMEKLGYQNTRVNSRTAGRESIWEKYGWGQTTPREMADILIRLNNRELFSPAASE -QMYRLLSNTFY-NDYAISGIPPGVNVASKQGMVN-ASRSEVFLVNSPQGD-YVCAIFTKN -NEDKDNEAWVMTRKLSNLVWNHf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura macra TaxID=46164 RepID=UPI00082DA05C ------ERIEAAFRDAGVTGFLHAVDVDTGRDV-ALRASAPVVLASVFKVPLLVAFHRQVA -DGTLDPSEQLTLRPQDRTAGPTGLSALLDEVMSLRDLACLMITVSDNASADVLLERV-GL -DAVNATAAALGLADTRIEGSGRELFEALDPAVTSRSTPRDMSHLLGRIWRDEAAPPAECA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -LLLDLPQADAVIGTAARLAVE-- ->[subseq from] zinc-ribbon domain-containing protein n=2 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI0009489173 -----KKDIGVTVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK -EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF -QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD -EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED -GEET--DQLAAMNKLGLM----- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces fungicidicus TaxID=68203 RepID=A0A494V2J7_9ACTN -----LARIDAAFADAGVTGRLHALDIDSGAQL-GTGADQPVCTASVHKLCLLVALHELAA -AGRLDLTEQVESPPADRTAPTGVAAMLDAARMSLRDLAYLMVAVSDNAAADLLLRRV-GL -DAVNATTARLGLTATLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACPPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -GHATLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535DR39_9CHLR ---ELVQHLDQLVSSFPGGAGLWIADPNAAKPLySHDADEPVITASLYKLAVLAEAERRVD -AGQLHYSDVITIENEDITEDGSF--EVAGTELTLDQALEAMITISDNGAALALWHVL-GA -DNINATLRNVGINDFHVFVA--------WGEDANVATPRAIGTLLTLLAKRQLISAAASD -RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD -AY--DADAYAFIANVGSIVYS-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. Go-475 TaxID=2072505 RepID=A0A2Z5K3U5_9ACTN -----LARIHAAFADAGVTGRLHAVDIDTGAQL-DAGADQPVCTASVHKLCLLVALHERAA -QGALDLTEQVDCPPEGRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLGRV-GL -DAVNRTTARLGLTRTRAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACPPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI0006B5D12C ---ETEKRIENVIHAFSGHISFYAEHMQTHETL-IHDSDHVMETASVIKLPIMAATFQYLV -DEHKSLADPLTLQVEDVVDGSGILQYLSPGLLSLKDVMTLMIIVSDNTATNMILRYV-GI -PHVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATAKELGTILTQLYHRTLVNKDASE -IMWDILCRQQY-NTIMTRHLPPRVQIGSKSGSLE-GIRNDVGIVVTPWGD-YVLAILSER -SRHIDNEALVVLPRISRFIFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Megasphaera genomosp. type_1 str. 28L TaxID=699218 RepID=D3LTR8_9FIRM -hdRTLQRIQQQLQSQDGIYAVYFQPCKAGALP-VIYNDHTMRSASMIKVFILSAAMEQIK -QGKMSFDQTITLQEADKVGGAGSLCGYPDGSVDVRTLLKLMITQSDNTATNLMIDLV-GM -DAINHYMQQHGYTETRLEWKMMA-QTAPGETRKNRTSVRDLGTWFRRVYEKKCVDPALDQ -YMIDLLLGQTD-TECFPTALP-EAKIAHKTGEVTN-LYDDGGIIFTSHGD-YILCIMTDQ -IAR--YDGIETMKKIARMLVE-- ->[subseq from] Serine hydrolase n=1 Tax=Inquilinus sp. KBS0705 TaxID=2578108 RepID=A0A554SNA5_9PROT ---KLSAQLQTATKGFNGTLGIYVQNLKSGKTV-EINADTLFPTASMIKVSILSGLMDKIE -KGELRYNQKLAYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-TG -EHINQWLDANGFKVMRVNSRTAGREAMRNIYGWGVSTPREMARLFTMIHDGKVVSPAASE -RMLRTLNRIYW-DNTALSQIPPNVQAISKQGAVDD-SRSETVLVNAPHGD-YVFSVITKN -NKAPTNEADILIKKVSALLWHYy ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus actinosclerus TaxID=1768108 RepID=A0A0U3T4A8_9DEIO -------------AGFTGVVGLHVTDLAGTELA-AWNAGRVFPAASTIKVPLLVLALQEAQ -AGRLDLSGRVVMQPGDRVPGAGVLHELDGGLLTWRDVLTLMIIVSDNTATNLVIGRL-GV -DAVNTWLAAGGLTGTRLVGKLEQRTEAQRRGERNATSARDQTALLRALVAGQLLDEAHTA -LALDILGRQQY-RDLIARHVPCGYRSATKSGELH-GVHHDVGVLFTP--YPLLVALLSEG -GADPR------------------ ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter terrigena TaxID=2492395 RepID=A0A4Q5LMH1_9SPHI --qKLTAQLQSLTKKFNGQAGIYVQNLKTGRTV-EINADTLFPTASMIKVSILGGLMDKIE -KDVMQYNQKLVYRDSLLYPGEDILGSFKDKDIQLSKVAMLMITMSDNTASTWLQKLV-GG -DYINTWLEQNGFKVMRVNSRIPTRRPIWEVYGWGVTTPREMCRLFTMIREGKVVSTAASE -RMYRMLNRIYW-DDKALSQIPPYVQAISKQGAVD-ASKSETVMVNAPHGD-YVFSIITKN -NKAPDNEAGLLIKKVSALLWHYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A4P5V4D6_9CHLR -------------------ASIAVVHLETGASA-TVNGDRIAAPASLYKIGVLVEAFRQIE -AGLLRLDETLRLLPIDWAPGAGILQGRIGTQVTITDALRLMIGISDNTAAHAIVRRI-GV -DRVNANNQRLGLSNTRY----------YIDDRPDTTTAADMARLLSLLATGRLAGVEATG -QMLDLLQQVQP-AAWLPRGVPPTIAVAHKSGQLD-AVRNDAGIVFGPTGR-YVVVVLTDN -RP-NAMNGENAIVQVARSVHAYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-37 TaxID=1463903 RepID=UPI0004CBDF42 -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVPTASVHKLCVLVTLHEQAA -AGLLDLTEQVECPPAGRTTPTGVAAMLDAVRMSLRDLAFLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A4Q9XZ01_9LACO ---QIKADISATVGVISGTNSVYVSPVDSHATV--LVNNESQRSASSIKIFIMVTAYAMAK -EGVFNLDDIHTITDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF -QLINNKIKSMGATDTKLRRKMMDIK-ALDAGRDNTTSACDMGITLKKIYNHQLVSQQADS -AMLTILANNQN-RTKLPKRLPDAATVYNKTGEYDYGVQNDAEIVKNQRGA-FVAVVLSEN -GEETD--QVDAM----------- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A2Z4MRX6_BREBE ---ELEKRLSTIIGQAEGTWGVVVEEVAKGIRF-EHVPNERFIAESVIKVPIMAAVFAASE -QGHFRLDDQLVLRQEELVGGSGILHALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIDQTMIDLGMRQSCYSRKLMIYP--LDVTENNTITAGNVASMLGHLATGSYLSEHACK -EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKE -VT--AQSALNTLGLLGRAVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1) TaxID=929705 RepID=A0A1W1W922_SULTA ---EAEKRIEDIVHAFSGHISFYAEHMQTHETL-TREPDRVMETASVIKLPIMAATFQYLA -DEHKILSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI -PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATSRELGMILTQLYHRTLVNKDASD -IMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH -SRHIDNEALVILPQLSRIIFDYf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura bangladeshensis TaxID=453573 RepID=UPI0013D18A53 --------------AAGVTGFLHVADMDTGREV-AVRAGEPVVLASVFKVPLLVAFHRRAA -AGLLDPAEQVTLAPGDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADAVLDRV-GR -DAVNAAAADLGLRGTVVEVNGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPDHCA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-VRNEVGAVEYPDGARYAVAVFTRS -TLAVLPRADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Melainabacteria bacterium TaxID=2052166 RepID=UPI001181FD1B ---DLKARIEQLFAEYKYTPHFYFYNPQTNTYV-EINGYGPAPAASVIKLPILLDYLMSLD -ENLITVDTPLLYAEFHRAGGAGELQYRPTGQFKANDVASQMIRISDNTCTNMMISYLGGT -DAVNQRLSDLGLVNTRIRNWLPDLTGT------NTISPYEMVTILNNIDHGPVISEVSRY -NGISILESTHN-RRLLVAPLPNQAIVAHKTGDIGT-AIGDSGIVYMPDGRKYYISMQVER -PYND-YTVRDMVQRTSRLLYDY- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A4U0M7H5_BACME -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu 4128 TaxID=1120314 RepID=UPI000F0152F5 ---ATAARLGAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHEQAA -AGTIDLTEQVECPADGRTPGPTGLSAMLDPVLSLRDAAFWMMSVSDNTAADLLLRRV-GL -DAVNRTTERLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A0L1LTY8_BACME -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora hirsuta TaxID=1837 RepID=A0A5M7C9B8_SACHI ------------AADLPGRVGFAAWDLAEREPV-LLGAERVVPAASTIKVLVMITALRAVQ -AGRIGLDDPLDLPAE-RVGGAGLLRQLRSIEISLRDLITLMIVISDNAATNAVIDAV-GF -DAIRDCAADLGCTGTRVERRLMHHHEP----GRNETTALDQARVLDRLAGGAALPPDLTE -HALGVLAEQQV-RDRLPARLPAGATCWNKTGELL-GLRHDVGLIGA-DRPRAVIAVLVDE -LTDE------------------- ->[subseq from] Serine hydrolase n=1 Tax=Bacteriodetes bacterium TaxID=2507565 RepID=A0A521X1W1_9BACT --------IQTTINELGGRVGISAKHISTGETL-TIDGDSLFPTASIIKLPVLVELFYQFH -EGKLSPDTPIPLLDDAKKPGSGILSYHNGQTLKLIDIATLMMIESDNTGTNYVIDQLGKL -NAVNNRMKSLGLQHTKLQNKLYSFATEAKRYGIGFTTPNDMLLLLEKIVKGEIVDRATSD -SIIAMMKGQQY-LEMAPRYLPSTLWTANKTGSLDE-VKNDAGIVSSSKGT-YIYAIFIDN -SPQIDNKATLTVAKISQILYNYf ->[subseq from] Uncharacterized protein n=1 Tax=Abiotrophia sp. HMSC24B09 TaxID=1581061 RepID=A0A1F1LPK4_9LACT --qAVQSAFSDLYGTKSTKLAYYFQEVTSKGTA-LVNQSGPIKSASIIKLFIMQVLLEEIK -AERISWQEIISMMAEDQVGGTGNLQAEPGTSYSLEELALEMLIHSDNTATNLIIERLGGL -SAVQAKIQSLGYQDTRLQRLMMDQ-AAIAEGRENFTSAREVGQLLAKLYQHKLVGQEQDQ -IFLDYLAQQTD-RQGLVALLPQGVISYNKTGTNSQGLQHDAALVQLTNQSAYVLVVLQEG -PGD--GDLLKPLQEIGQQV---- ->[subseq from] Beta-lactamase class A n=2 Tax=Saccharopolyspora TaxID=1835 RepID=A0A1H6EKX4_SACHI ------------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ -AGRIGLDDEVELPAE-RVGGAGLLRQLRSVDISLRDLITLMIVISDNAATNAVIDAV-GF -AAIRDCAADLGCTGTRVERRLMHHHEP----GRNETTALDQARVLDRLARGAALPPELTE -HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGT-DRPRAVIAVLVDE -LTD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Caulobacter vibrioides TaxID=155892 RepID=A0A0V2F688_CAUVI --eAMSLKLAAIAERAPGDLGVAVQDLTTAQRA-ATAGDHLFPLAGIWTAALGAAVLAEVE -AQALSLRETLTIEDVDLSPPSGVADVWPGRRWTVEELLKRAVADGDNTAADVLMKRIGGP -GAVTAWLDLKKVENLRVDRYARQLLPDYLADPHDSTTPLAAVRFLEALNQGELTDQDGRR -RMLRMMEAAA--GDRLRPALPAGARLAAITSATPAAADNVLAMVRLKDGRRFALAMFLKA -SPLEEADRDALMLDVMRTVLQ-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGD-10 TaxID=2493089 RepID=A0A426HB95_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA -LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPGGRDGATVVVACAE -HFGELEQAEQAFQALGRALA--- ->[subseq from] Serine hydrolase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N9I579_9PSEU -----AAEIAAVFADAGARGFVHARQVGDGPEV-AVGADDQVVLASVFKIPVAVAYAREVA -AGRLDETERTRVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRV-GQ -AAVDQVLADLGLARTRLIGCCEDLFAVVDPDRTTSSTPREITALLDAIWTGRAGDPAACE -RVRTIMAQQIW-PHRISSGFPTGVTIAAKTGTLP-AVRNEAGVVTHVDGRQYAVAVFTRA -DCDRLPAVDAAIGQAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces silvensis TaxID=1765722 RepID=A0A0W7X493_9ACTN ------TRLKEAFAEAGVTGRLHALDIDSGAEL-GTGADHPVVTASVHKLCVLITLYEQAA -AGLLDLTEQVECPPDGRASGPTGLSAMLDPVMSLRDAAYLMIAVSDNTAAELCLSRV-GL -DAVNATTARLGLTRTRALHTFRAMFEALDPARSNHSTARDMTRLLRALWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ARATLPPADAVIGTAARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora TaxID=1835 RepID=UPI000B81E7A7 ------------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ -AGRIGLDDEVELPAE-RVGGAGLLRQLRSVDISLRDLITLMIVISDNAATNAVIDAV-GF -AAIRDCAADLGCTGTRVERRLMHHHEP----GRNETTALDQARVLDRLARGAALPPELTE -HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGT-DRPRAVIAVLVDE -LTD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Actinobacteria bacterium OV450 TaxID=1592328 RepID=UPI000D14BB10 ------HRIGAAFAEAGVTGRLHAVDIDSGAQI-DAGADHPVVTASVHKLCLLVALHQQAE -AGRLDLTEQVEVPPPDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLART-GL -DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAALWRDEACTPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTTARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Ktedonosporobacter rubrisoli TaxID=2509675 RepID=A0A4P6JVW5_9CHLR -----QEQIEQELARLGGRSSCIVMRMEKQDLV-SINPNTLYPAASLVKVPILLEVARQVA -SGRLSWEEGHAVPEAARATSAGVLADLSAELLSVHDLAHLMITISDNTAANVLLDLV-GM -DAVNATMQELGLPSIRLERHFMDLEAR-AAGRDNWATAGDMARLFAYLCTPEV---PERE -HIIDFLLQQND-TTILPAYWGEDIPFAHKTGGLA-GIIHDAGILFPQQKMPLIIVAMTAD -QS-DEPLTRYVLARVGQLIYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium OV450 TaxID=1592328 RepID=A0A0N1NMR3_9ACTN ------HRIGAAFAEAGVTGRLHAVDIDSGAQI-DAGADHPVVTASVHKLCLLVALHQQAE -AGRLDLTEQVEVPPPDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLART-GL -DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAALWRDEACTPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTTARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-893 TaxID=2682778 RepID=UPI0013EB7C49 ---NLAATVSGIISSYGANASVTLSDLDDYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN -NGYLALEDSYTVQESDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM -DAVNEEAAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ -LATDFLSQQTD-AGGIAGSLSSGETFAHKTGTLTN-VRHDAGIVQ--GEAPYVLSVFVEG -TDEG--SALSLMGEVT------- ->[subseq from] Beta-lactamase class A n=1 Tax=Aminivibrio pyruvatiphilus TaxID=1005740 RepID=A0A4R8M6U0_9BACT --------VHKEIEAFPETAGVVVRSSSDGVEV-THNPGKVFSSASLIKLGVLYTLFSKNA -AGGIDLDEWCDFSSAASVDGGLLHRVRSGGRFRLDDLALLMISVSDNTAANLLIDRL-GM -DTINGGFRELGLTGTVLGRKMLDFEAK-KAGKDNYTTAGDVAVLLETLHSGKNLPVSARN -RMMEILSAQKL-NSKLPGMIPVELFLAHKTGELP-GNEHDAGIFFYRGKKPVVVSVLTEG -LQ-HRSGGVSFCARIGRIIYDAy ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-134 TaxID=1081603 RepID=A0A542WCQ7_9ACTN -----LARIDAAFADAGVTGRLHALDIDSGAQL-GTGADQPVCTASVHKLCLLVALHELAA -AGRLDLTEQVESPPADRTAPTGVAAMLDAARMSLRDLAYLMVAVSDNAAADLLLRRV-GL -DAVNATTARLGLTATLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACPPEHGA -AVRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -GHATLPAADAVIGTAGRIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02488 TaxID=1703920 RepID=A0A1Q5NC16_9ACTN -------------------LHVAELHRPSARVV--IEPGEQLPLGSVYKVPLMAAFCRLAD -TGRLDPRHRVTLEPADRVPPTGISVLHDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA -DAVDAFCRDLGMPDTRIHGGVVATFSVYDPASKASGTPADMARLLRAIWTDEAASAEGCA -FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 7K502 TaxID=2530387 RepID=A0A4R4YJC4_9PSEU ----VERRIREVLADAGAEGWVHAKPLNSEREI-DVGGDELVVTASVYKLPLLVALCRAFD -AGALDPRARVRIDPASCTPGPTGMSAFQDPVVSWRDLAASMIGVSDNAAADLILGEV-GL -DALADTLADLGLSRTRVVGGTADSHAAYDPSYASATTPREMTRLLELVWADAVASPEQCE -FIRRLLANQAW-QHRIRAGFPRGVRVAGKTGTIG-AVRNEVSVVEFDGETPVAVAVFTLA -ARADAPGVDAAIAECARIAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Desulfovibrio sp. X2 TaxID=941449 RepID=S7TKB6_9DELT ------------------------------------------------------------- ------------------------------------------------------------- --------RDARDGATRLDRAEPELNEATPGDPRDTTTPAAAAASLAAVVLGDALAPSSRA -AVTDWMLHDQVADGLLRAALPPDWRIADKTGAGGHGSRSIIAVVWPPERKPLVVAIYITQ -TEAPLPAANLAIARIGRVL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Deinococcus peraridilitoris (strain DSM 19664 / LMG 22246 / CIP 109416 / KR-200) TaxID=937777 RepID=K9ZXE4_DEIPD -------DLQFLLASHPGTVSVRVLSLQGEVLF-DHQSERPFPSASLIKVPLLVRALWHVQ -QGQARLEERLTLRAYERVPGSGVLSQLDAGLLTLRDVLTLMTVVSDNTATNLVIDRF-GL -HDVNVFLREAGMNNSELIGQLQRQNERQRAGERNRTSAHDISRLLLRLVRGELLSPALTD -LALDILSRQQV-RDIIARHVPRGYRVASKGGELS-GVRHDAGIVWTP--RPLILALLSEG -GSLREHPDNR------------- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium sp. 1.A.4 TaxID=2044603 RepID=UPI000C0BCFF0 --kKLTAKIQQEINGFRGDIGIYVKNLKSKKEV-RISADSIFPTASIVKVPLLVGIFQKID -ANEVQLEQKFIYSDKRTYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWIQELAGGG -QTINPLMDNLGLKNTKVNSRTAGREDIWKKYGWGQTTPYEIAHLFELIREGKVISEKQSD -KMYRFLKNQFY-NERSLSQIPAIYATISKTGSVND-ARGEVVLVNAPHGD-IVFSILTKN -NKTKDNEAENLTRRIAKIIWDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1I2T6J6_BACME -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILGLTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMQGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Nocardia donostiensis TaxID=1538463 RepID=UPI0009DAFDD3 ---------------------------GSADEV-SVGGGERVVTASVYKLALFIAFCRCVD -AGLIDPAEPLTVHPAECTPPTGIATLHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -RAIEDLLTGLGLTQTRIVGGTADIHRAYDPAYTSATTPEEMTRLLREVWSGAVLSPGQTE -FVRAVMRNQIW-PHRIASAFPRGVSVAGKTGTVGI-IRNEVAVVEFPDEYPVAVAVFTRA -ARADLPIVDAAIAETARVAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. KNHs216 TaxID=1550235 RepID=A0A542ANK0_9CLOT ----LRDYAENEIQDINAKVSLLVYDFDQDETLlSFYEKDRVVSASTIKTPILLTALDMVQ -SGKLSVGQMLRLPGEEILDDTEVFDRGVR-EYPLEELLTWMIINSDNTATNVLIEFL-GM -DAVNACCRKLGLKATALERKMLDWEA-VRQGRNNYTSAQDQLTVFQSLRRASILTPELCR -CALGILERQRDFSMALRYIADRDFSAAHKTGGLDY-LNHDTGIFSLPGHE-YYFGCFVTD -STDDTDENKKLIGRLSRKVYDYy ->[subseq from] serine hydrolase n=1 Tax=Nocardia salmonicida TaxID=53431 RepID=UPI0007A4B5F6 ----------------------------SAGEV-SVGGHDRVVVASVYKLLLLAAFLRQVD -HGLIDPAGRLTIDPADCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -AAVGELLQELDLTDTRIVGGTADQHLAYDPSYASATTPEEMTRFLWKLWSGNIVSTASTE -FARTAMSKQIW-PHRIAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Kribbella flavida TaxID=182640 RepID=UPI00059B712F --------LSGVFDDAGARGWFHAVSLDRPDEQiALDADHVVPMASVYKLPLVVAFSELVD -RGELDPRQPLTLEPGDRTPPTGVSILSDPVTMSLRDLAASTMAVSDNAAADALLEVV-GL -DRVADFLRRHGLTDTRVRRGTAGNLRIYEAAGGSSTTAQDMTRLLAMLWAGAILSAEQTA -FVRRLMELQVF-GQRIAAGFPDGVRVYGKTGSFG-ALRHEVGVVELPGGPTVALAVFTRA -ARADLPRVDAAIAHAARYAAD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. AG236 TaxID=2184002 RepID=A0A369C456_9BACI -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRK -KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522E036_9BACT --kRLQKELEAVVKEFNGDIGVYIKNLRTGKTI-AINADTIFPTASIVKVPVLIGIMDKIS -KGELLYDSTLIYKDSLLYEGEDILGSFKSDEILLKKVIMLMLTTSDNTASLWLQSLAGKG -TRINEILDSLGFKNTRVNSRTPGRENNRTQYGWGQTTPMEMGTIFEKIYLNEIFSAKACD -RMMRCLGRNYWDVDEAVSQIPPYIEVFSKNGCVD-ASRSEVLLVNAPHN-PYIFSIFTKN -NKTHNNEAWTLARKISALLWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax intermedius TaxID=433924 RepID=A0A370FPT8_9BURK ------------------------------------------------------------- ---------------------------------------------------------RNGP -ARVEAIRRAADVKRTDLATTMDEAYDRYYRRDLNTTTLIAYGAMLERLVRGQVLPDAPRA -LLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. OK519 TaxID=2135729 RepID=A0A2T5KLY3_9NOCA ------------------------SDGHGGIEI-GTAADEPVVMASVYKLPLVVTFCRLVD -AGDLDPREQVVLDPSNRTTPTGVSQLSDPVRMSLRDMARSMMALSDNAAADELLRRV-GV -DRVNETMRGLGLSSTRIVGGTSDILEGYDPVLSSATTPRDMTGLLSAVWTGAALSAEQTA -FVRGVMASQVF-TARLRSGFPGDVVVAGKTGTLG-AVRNEVGVVEFPDGDAFAVAVFTRA -ARADLPRADAAIGIAARAAI--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces violaceorubidus TaxID=284042 RepID=UPI0004C2A11E ---ATAARLDAAFAEAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVALHELAA -AGELELTEQVECPPTGRTPGPTGLAAMLDPALSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRATARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGALWRDETCPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium UBA8153 TaxID=2060924 RepID=A0A3C0FFP9_9FIRM --eKLRHQVEEITSSVPGTIGVAVKDLATAEEF-HYQADQLYPLASVFKIPILVELYRQSG -LGLVNLDERYTLTAGIKSLGSGVLRDRPGATMTLWDYALLMIIISDNTATDLVAGVV-GI -HHVDPTLRRLGLERTSVTKDCYHLLCLYPEPTHNFSTPREMNRLLGQLVEGELLGPPEQA -GVMDILLRQQL-KQRLPYLLPRPVPVAHKTGSLP-GVFNDCGIVFRDKQPAYLISLMSKG -VS-AALEGPLVLARVSRAVYDA- ->[subseq from] Beta-lactamase class A n=2 Tax=Granulicatella balaenopterae TaxID=137733 RepID=A0A1H9JSX6_9LACT -----------------GNHAYYYQDLSTSEAF-GANQDTPIRSASIIKLMILAALYQEVA -DGQIDLTDSYYLKAEDIVGGTGQLQQTLGTRYSYYDLAYQMIYSSDNTASNVIIDKLGGL -AKTNQLFKQLGFKKSNLQRKFVDTNA-LYQGLDNYVTAFELADLLSRLYQHQLVTPASDR -AMLAILKENPN-RDIILKKLPRNITSYHKTGNYSYGTWNDAGIFVTDKGA-FILVSLTSG -GQ--FQQKKTATANFA------- ->[subseq from] Serine hydrolase n=1 Tax=Frankiales bacterium TaxID=1909291 RepID=A0A522B6L9_9ACTN ---DVTAALTDVFSRAGAVGRLHAREIGTGHEV-GLGADEPVVLASTFKVPVALEVFAQAA -EGGLDLSERVRVPVEGRAPGPTGLSVFSHEALSLHDLARSMITVSDNAATDVVCERV-GL -DRVAARLGALGLDEIVIPYDCRGIFAALDPLQTDRGTPRAMTRLLELIWTDTAGPADACA -QVREVMAQQVW-PHRLTAGFPADVTLAGKTGTLPS-QHNEVGVVGYPDGRSYAVAVYVRS -ARFDQPLLDRAIGEAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Gelidibacter salicanalis TaxID=291193 RepID=A0A5C7AJP2_9FLAO ----LENGLAELAQGFEGDVGIYVYNLKTQKEA-AINADTIFPTASIVKVPILIEVFNQIK -AGKLHLKDTLIYDAKRVYGGSGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELVGGG -LAINKTMADLGLKHTRVNSRTEGRTEDWETYGWGQTTPREMASLLIQMRERTLVDEAASD -EMYRIMGNSFYTDYSL-SQIPPYVQTAAKQGMVNK-SRSELVMVNAPSGD-YVFYIATKN -NADENNKAWELQRAISAYLWNYf ->[subseq from] Beta-lactamase n=1 Tax=Intestinimonas butyriciproducens TaxID=1297617 RepID=A0A0S2W0G7_9FIRM ---ELSAYLAAEIAAFPGKTSLLVADLPTGAVRhAWQPEEPVPSASTIKVPILLAALEEVR -LGRLSLEQRVALPAAALLPDTEVFDR-GETDCSLWELLYWMTALSDNTATNVILDLL-GL -DAVNRYATRLGLRHTVCRRKMLDAAAA-AAGRDNRTSAADQCRLYRQLCLGRLLTPRLTE -TALDLLRRQRCMDAALR-YLPYPVDFAHKTGELD-GVTHDAGVFFQGSGG-YYLGIFTWE -GPDGDPEQKRYIGRLARAIYETy ->[subseq from] Beta-lactamase class A n=1 Tax=Desulfallas thermosapovorans DSM 6562 TaxID=1121431 RepID=A0A5S4ZXC2_9FIRM ----LQEQIAGYLDKQPGVYGLYFIDINSGRGF-GYNSRTVFHAASTFKVPMNLYLYRAAD -QGQLNLSERLFFRDKHLEGGTGILQNQPPGEYTIAQLADYSILYSDNVATNILLDRL-GK -ENVKEFMRSLGGQVVD--------------NEQNITCPRDLALYMQEVLR--LARQPAGE -KLLENLFDNKL-KDRIPAPLPPDIKVANKIGTWPSETYNDVAYVAHPKQ-PYILVVTSKE -TP-GYREAVAVIRHLSELVYRY- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura amylolytica TaxID=1411117 RepID=UPI000E6B5B2B ---RVAARIERAFRDAGVVGCLAAIDVDDETRRvEVRADEPVVIASVLKVPLLVAFYRQVA -AGRIDPAEQVVLRPDERTAPTGIGMLRDEVRMSLRDLAAMMITISDNAAADALFARI-GA -DTVNAVLDELGLHRTRVPGGCRELFDALDPARTACGTPAEIARLFAAIWRDEAAPPAECA -QMRRIFGLQVW-PHRLASGFPDDVRVGGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS -LSAVLPQADAVIGTTARLAVEH- ->[subseq from] Serine hydrolase n=1 Tax=Luteimonas sp. XBU10 TaxID=1132694 RepID=A0A5D4XSS6_9GAMM ------------------------------------------------------------- -------------------------------------------------------NAAAGE -PRLQALARTLGVARDALPKSLQDVFEDYYATGANAATLPAFARLLQRVAAGELLSDAGRA -RLLGHMRAISTGDRRIAAGLPAGTDFAQKTGTQL-GRACNVGILEPGLGDGATVVVACAE -RFGDLAQAERAFQALGRA----- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium hathewayi CAG:224 TaxID=1263067 RepID=R5TPL2_9CLOT ----IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEAFETASTIKTYILACLFDQVE -KGKASLEDMVEYKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA -KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK -FSDAAHPATVFGARVSRLLFDQf ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A3D1IAC0_9BACT ----LQKRLDAVCRAFHGRMGYSLIVLKTGQRI-SFRGDERFPTASTIKTAVMVEAVNRVD -EGTLKWSDKRPVPPESGREASMWSYFFKDGVPDLDGWVNLMIGVSDNTATIVLREWL-GI -EAINARMERLGLTNTMVLGPVPPEKQLRSVFGLGVTTPNEMARLLELIYRGKAASPGGCE -KMIRILGRQYW-DDLIGATVPPDVKTALKSGAISR-SRSDTGIVFSDN--PYVLCVYTDN -QKAPDNEGEVAIRKIAQMVWAH- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura rudentiformis TaxID=359158 RepID=UPI00124CD9A0 ---DATARIEAAFQDAGVTGFLHATDLDTGREI-GVRADEPVVLASVFKVPLLVAFYRQAA -AGLLDPREPVTLRPEDRGDPTGISVMLDEVRMSLRDLACLMITVSDNTSADTIMDRV-GV -GAVNDAVAELGLHRTHVAGTGSDLFDALDPLTTSRSTPREMARLMGMIWRDEAAPPGECA -QMRRLFGLQVW-PHRLSSGFPDDVRVSGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS -PTAVLPQADAVIGVSARLAVE-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Oceanobacillus picturae TaxID=171693 RepID=W9APF4_9BACI --------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQID -SGRLHPDKLVYIEEEQFVGGSGIISYLTNSHYSYMNLIELMMIVSDNTAANVLLESL-GM -EAVNQTIEQLGAKNTIVQRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEKYISSKSRK -FMRSILAKQQL-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEE-RVYITVLSDH -LP-SNAEGQHTIAQIGKHAIDY- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus cellulosilyticus NBRC 106333 = KACC 11606 TaxID=1223518 RepID=A0A511NAX4_9DEIO --------LAELVQRFDGELSLCVSDLQGEMLF-CHEARQVFKAASLIKLPILSCALKTVE -TGALSLQDRLPLAAQDQVPGAGVLHEMETGLLTVKDLLTLMIIVSDNTATNVLIERL-GR -DTINRHIQQIGLKDTFLVGKLPELQNEQRTGQRSTTSAADMNLWLLKLWQGQLLNPEHTA -LALGILKKQQD-RLVIARRLPRNFEVASKSGEIQY-HRHDVGIVFAE--KPYAVSLLSRG -SKDLRE----------------- ->[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2XCK5_9FIRM --qQLDRIFSHIADNFSGTFTVYAEHFKTGEVI-AFGNSHPMETASTIKLPILITAMQKIH -EGHLHMEQLVPLLPDDYVTGSGVLQNLSLGTLPIADVLMLMIIVSDNMATNMILRLI-GL -DAINRLMQDLGARNTVIRKRID-FR--IPP-PIGLSTPKDMVHLLKGIYHRQLVSPAASK -WMWDVLTRQQY-NTILTRNMPPQVIIGSKSGSVE-GVRNDVGIVTTPWGD-YAIAIMSEA -CQHMDNEAHRVLPEVALQVFQHf ->[subseq from] Serine hydrolase n=1 Tax=Paenarthrobacter nitroguajacolicus TaxID=211146 RepID=A0A558GVI4_PAENT ------EELAEIFAAVGATGYVHAREVGGGREV-SLNPDEAVVLASVFKVPFAVAYSREVS -AGRLKESDRTTVTSRYRVGGLGTAGCADDVEMSWRDLAKFMMTMSDNAATDVIFHRI-GQ -AAVDAVLDDLGLQRTRIIGCGEDMDHIMDPARTPSSTPRDIVSLLDAIWTNSAGSPETCE -RVRSMMEQQIW-RHRMATGFDDGVVVAGKTGTLP-AIRNEVGVVTYPDGRRYAVAVFTRA -TTDTQPGIDASIGKAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. SGNA-20 TaxID=2493088 RepID=UPI000F635068 ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALADALGVPRAELGDTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA -LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPAGRDGATVVVACAE -RFGELEQAEQAFQALGRALA--- ->[subseq from] Beta-lactamase n=1 Tax=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) TaxID=479435 RepID=D2PZW8_KRIFD --------LSGVFDDAGARGWFHAVSLDRPDEQiALDADHVVPMASVYKLPLVVAFSELVD -RGELDPRQPLTLEPGDRTPPTGVSILSDPVTMSLRDLAASTMAVSDNAAADALLEVV-GL -DRVADFLRRHGLTDTRVRRGTAGNLRIYEAAGGSSTTAQDMTRLLAMLWAGAILSAEQTA -FVRRLMELQVF-GQRIAAGFPDGVRVYGKTGSFG-ALRHEVGVVELPGGPTVALAVFTRA -ARADLPRVDAAIAHAARYAAD-- ->[subseq from] Putative beta-lactamase n=1 Tax=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) TaxID=927704 RepID=I0GNU3_SELRL ---ALAEKITALSNADSTRYSLYAAYPQENRAP-YIYQSEPMRSASMIKVFLLANAMEKVR -DGQLSLDMGITLHSGDKVGGAGVLCGYPSGSIPLDKVLRLMITESDNTATNLIIDLL-GM -DDINAYIRRNGYHDTTLARKMMDFAA-VNAGRENYTSVTDLGNLFQKIYHHDCVGYEQDE -IMLSYLKGQTD-RECFPAALP-SAVIAHKTGELG-GLYDDGGIIYHSNRD-MIFVIMTEH -YS-SRYRAIETMKSMAQIAF--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis X23 TaxID=1200792 RepID=A0A291BUF6_BREBE ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AKIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGNVASMLGQMATGSYLSEHACK -EMIAIMKKQQV-RNGLPSQLPSEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID10853 TaxID=2706028 RepID=A0A6B2S468_9ACTN -----QRTIRGMFADAGVRGWLHVAELRRPTAYvSVDPDEPVPVGSVYKMPLMVAFCRLAD -SGAVDPRLRVTLEPSDRMPPTGISVLRDAVSMSLRDLVALMMTISDNTAADAVLRRI-GT -AAVDEVCRDLGMRDTTVHGGVATTFAVYDPLSKASATPADMALLLRAIWTGRAASAESCA -FMRGLMGKQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELPDGSAYTAVVFTQA -ARADLPRADAVIGAAARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5789 TaxID=2690310 RepID=UPI001369803B ---ATAARLGAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVALHEQAA -AGVLDLTEQVECPAEGRTPGPTGLSAMLDPVLSLRDAAFWMMSVSDNTAADLLLRRV-GL -DVVNRTTERLGLTRTRAVYGFGEMLSALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SM1 TaxID=402229 RepID=UPI000CD5B8A6 -----VARIHAAFADAGVTGRLHALDIDSGGQL-DAGADQPVPTASVHKLCVLVALHEQAA -AGLLDLTERVECPPVGRTPPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTARLGLPRTLAVHSFGDLLAALDPARTNRSTPREMTRLLAAVWRDEACTPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPVADTVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013E360C0 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECTKDLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Pedobacter ureilyticus TaxID=1393051 RepID=UPI00110D0BF3 ---KLNKMINELAKDFNGDVGIYVKSLKTGKIA-AFNADTIFPTASMIKVPITCGIFDKIE -KGELDYKAQLTYKDSLLYAGEDILGSFKNGEIWLTKVLMLMITTSDNTASLWCQSLAGTG -VAINNLMAQYGLQHTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIRDGKMISPAASE -RIYRNLIRIYY-DKEALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCITTKN -QKDTDNEGEVLVRKLSKMLWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura mexicana TaxID=134959 RepID=A0A238WSY3_9ACTN -----AERIEAAFRSAGVTGFLHVVDIDTGRDV-AVGADEPVVLASVFKVPLLVAFHRLAA -EGVLDPAEQVTLSPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADVVMDRV-GL -DAVNATAADLGLRHTVIVGNGRDLHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPAGSA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS -MLAVLPEADAVIGSAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter phyllosphaerae TaxID=1812349 RepID=A0A4Y8AK18_9SPHI --qKLTAQLLAATKGFHGDVGIYVQNLKTGKTA-AINADTLFPTASMIKVSILSGLMDKID -KGELQYNQKLVYYDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-GG -DYINNWLDANGFKAMRVNSRIPARRAVWEKYGWGVTTPREMCRLFTMIREGKAVSPAASE -RMSRTLNRIFW-DETALSQIPPYVQTMSKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN -NKTSDNEADVLIKKVSALLWHYf ->[subseq from] Beta lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D9W717_9ACTN ----ARRTIRGLFADAGVRGWLHVADLRRPEACvAIDPDEPVPVGSVYKVPLMVAFWRLVD -AGTLDPCERMTLGPSDRIPPTGISILRDDITVSLRDLVALMMSVSDNTAADVLLRRV-GT -PAVDEVCRDLGMPDTRIHGGVATTFAVYGPVLKSSATPADMARLLRAIWTGRAASAEACA -FMREAMGRQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia alba TaxID=225051 RepID=A0A4R1FZY8_9NOCA -----------------------------AGEV-CVGGRERVVIASVYKLLLLATFLRQVD -HGLIDPAGRLTIDPADCTPPTGLAALHDPVTLSRRDLATSMMTVSDNAAADVLLGEV-GL -AAVGELLRELALTDTRIVGGTADQHRAYDPSYASATTPEEMTRFLWRLWSGDIVSTASTA -FARTVMGKQIW-PHRVAAGFPRGVLVAGKTGTIGV-IRNEVAVIEFPGETPVAVAVFTRA -ARADLPVVDAAIGEAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Cyanobium gracile (strain ATCC 27147 / PCC 6307) TaxID=292564 RepID=K9PBQ3_CYAGP -----SQQWARLAAQKGLTASGFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD -RGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK -TELNSRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD -LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQMPNGQRAVLAVMVKG -PFND-PRSAELIRAMAGAVTK-- ->[subseq from] Beta-lactamase class A n=2 Tax=Clostridiales TaxID=186802 RepID=A0A2U1CFW4_9FIRM ---ELSAYLAAEIAAFPGKTSLLVADLPTGAVRhAWQPEEPVPSASTIKVPILLAALEEVR -LGRLSLEQRVVLPAAALLPDTEVFDR-GETDCSLWELLYWMTALSDNTATNVILDLL-GL -DAVNRYATRLGLRHTVCRRKMLDAAAA-AAGRDNRTSAADQCRLYRQLCLGRLLTPRLTE -TALDLLRRQRCMDAALR-YLPYPVDFAHKTGELD-GVTHDAGVFFQGSGG-YYLGIFTWE -GPDGDPEQKRYIGRLARAIYETy ->[subseq from] Class A beta-lactamase (Fragment) n=1 Tax=Hymenobacter sp. TaxID=1898978 RepID=A0A519Z910_9BACT ------------------------------------------------------------- --------------------------------VTVKELLTYMLVVSDNDACDILLKLLGGP -RQVMAYVRHLGVKHLVIKASEAQMGAAWPVQYTNWSYPSAQIELLTIVYRQTALTKPSNE -LLGQLLLATSVGPMRLKGLLPPGTPVAHRTGTSATNATNDVGIIQLPDGRHLAMAVFVSD -SYADLATRELVIAQLAEAAYKEf ->[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. CPCC 101110 TaxID=2599619 RepID=A0A5C5UQB6_9BACL ----LKQKIEERLLKIDGI-GSLFIE-TEGQSI-TINPDRKMKAASVIKLPILLEGYRQID -SGIISGTDRISLSKKELVGGSGILAHLESVRLSVHDILMLMTIVSDNTASNLAIKHL-GM -ENINGLTAMLGCTNTVLGRQFMDLEAA-EKGLDNFTSARDMVLCLKEADTGKTLAKKSRQ -QVIHTLKQQQL-TANLHGRIDSEVSIASKSGSLS-GVVNDVGMIELSGQK-VYVAVLLGD -LP-DNHTGQEIIADIGWYIHE-- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644ZGV3_9ZZZZ --qALDAYLNSEIRKFPGKSSVLLADVDTGEIHfATNPHSPVVATSTIKVPILLSALDQVK -QKKLSLAQPIAVPDDRILPDTQVFEL-GQSDYSLWELLYWMITMSDNTATNIILDLL-GM -ETVNEYCNSLELAHTRVARKMLDFDAA-AEGKENFTSAYDQYRMYCHLCHGRLFSRQLTK -VALDILARQRSTD-QFLRYIPRTVTVAHKTGTLD-GISHDSGVFFLPHMRCYLGVFTWDG -PSEGNPSQKQFVGRLARAVYTTf ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga barathri TaxID=1647451 RepID=A0A3N4MG29_9BACT --rKLEKALAAMVGEFKGTAGVYVLHVPSGRFA-AVNADTIFPTASIVKVPLLVGLFDKID -KGEVKWNQPLVYHDSIKYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLWNQALAGGG -AQVNILLEKYGLKDTRVNSRTPGREEDRKVFGWGQTTPREMSTLLLKIRNGEVVSKGASE -KMYRLMTKGYY-DNQAVSEVPPYVQVAAKTGSVNE-SRSELALVNAPHGD-YVFYVGTKG -IKEEENEAVQLIRKVSAYLWAYy ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. LM3 TaxID=1938608 RepID=A0A1T1BE52_9DEIO --------------GFAGTVGLWVGTPQGEALA-TLNVDRVFPAASTIKVPLLVMALQAAQ -RGDLSLDGRVTLSAQDRVPGAGVLHELGAGLLSWQDVLTLMIIVSDNTATNLTIGWL-GV -GAVNGWLGAHGLNGTRLVGKLDQRNEAQRRGERNATTAADQARLLRLLLGGDLLDPPHTA -LALSILGRQQY-RDLIGRGVPAYYRVASKSGELT-GVHHDVGVIFTP--RPLVVALLSEG -GQREHPENRDVTALA-------- ->[subseq from] Uncharacterized protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A6B8Q6Z5_LACPN ---QIRNDISSTVGAISGTNSVYVSPVNSKQAV--LVKDGSQRSASSIKIFIMVTAYAMAK -EGVFNLTDTHTVTDSEKVGGTGVIQNMDAGTLSYQEIIEHMIDDSDNTAANIMIEKLGGF -DLINNKISNMGATDTKLRRKMMDTK-ALDDGKDNTTSAHDMGMTLKKIYNHQLVSRQADE -AMLTILAKNQN-RTKLPKDLPSSATVYNKTGEYDYGVQNDAEIVKNSHGA-FVAVVLSED -GDQ--NDQIDAMNRLGSLLYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YIJ2_9CHLR ----LAGEVVSVLRGRDESVSIAAVHLLDGTGV-ALNADDVVPPASLFKLNILAETYRQIE -RNRVKLAQMITILPEDAAPGAGILQDRIGEAVSVGEALSLMIGISDNTAAFALLRTI-SS -RKLNECTRALGMLRTWFYVDER----------PDETSAGDVVTILRAIIDGTIASPRGTD -QMLELMTQVQS-SAWIRSGLPPGTRLAHKSGQLE-GIRNDAGIVFGPTG-PYALAVLTHD -LY-DPAVGEQIITAVTRVVHRYf ->[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae TaxID=186803 RepID=UPI00040B41F9 -------EIIEKLERLPGKISFLYENLETGDGF-SYHQQEPMMAASVIKLFVMAAAFEKEK -RGTFSMDEMFSVKKEDRVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM -EEINEIIRGLGFRQTLLQRKMYDMERS-GRGIQNYITAHETGRLLKMMYNGVLIDRQSSK -TMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEVSLDLY--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7EJ66_9ACTN -haRARDRIRAAFAEAGVTGWLHAVDIDSGAQV-DAGADHPVVTASVHKVCVLVALHQQAE -KGRLELTEQTECPPDGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAADLLLHRV-GL -EAVNATTRRLGLTRTHAVQTFGEFVAALDPASTNRSTPRDMTRLLGAVWRDEACAPQHSA -AIRRLLSLQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVVEYPDRGRYAVAVFTRA -ASPALPAADAVIGTAAHLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Terrimonas sp. YJ03 TaxID=1104781 RepID=UPI001264118C --kKLQSRIADAVSGFNGTVGIYVHDLKHNKVA-YFNADTVFPTASIVKIPILLGIMQKIE -TGELNYHQRLMYRDSLFYDGDDILSRFKDSAIELSKVMMLMITISDNCASLWLQALAGSG -TRINEIVDSLGYTSTRVNSRTPGREENRRIYGWGQSSPREIAGIMEKIVRGEIYSKAASD -RMLRLLGRQYW-DEQALSQIPAGVFAADKTGAVD-GSRNEVLYVNGKKN-PYIFSIFTKN -NKNENNEAWMMTKKISALLWAYy ->[subseq from] Serine hydrolase n=2 Tax=Streptomyces sp. A0642 TaxID=2563100 RepID=A0A4S2UZY0_9ACTN ----------------GVRGWLHVAELHPSARV-TVDPDEQLPMGSVYKIPVMVAFCRLVE -AGRIDPVRRVTLEPGERVPPTGISLLSDAVTMSLRDMVVLMMTISDNTSADAVLRAV-GP -DVVDAVCRSLGMPDTRIHGGVVNTFSVYDPAYKASTTPSDMARLLRAIWTGQAASEEHCA -FMRGVMRQQPW-AHRLGSGFPDDVTVYGKTGTFGS-LRHEAGVVELADGTTYTAVVFTQA -ARSDLPRADAVIGAAARAAVE-- ->[subseq from] ClassA_beta_lactamase (Fragment) n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A059WGG9_9BACT ------------------------------------------------------------- ---------------------------------TVAELLESSIVRSDNTSTDKLLPLIGGP -AGVTDRMRTLGVANINIKYSSREFAA--HRDKPNTGTASDLAKLLAKLQKGELLQPAQLS -LLLGFMEKARTGERRIRANLPAGTQVAEKTGTGD-GTTNDVGLITLPDGGHLAIAVLITR -SKVSPEAQEKVIAELARAAYDA- ->[subseq from] zinc-ribbon domain-containing protein n=2 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI00111BC2B6 -----KKDIGVTVGAIGGTNSVYVSPVNSEQSV-VV-NNGSQRSASSIKIYIMVTAYAMAK -EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF -QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD -EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED -GEETDQ----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Cytophagales bacterium TFI 002 TaxID=1945892 RepID=A0A286IKF4_9BACT ------NSLDSYFKELDPEIGVSMQLMNKEGEV-LFAKDDTVPAASTIKVPILIAYYVALE -KRLFKAKAKYELNEEVKVGGSGIQYANAMTEYSLDQLALEMIRVSDNTATNIMIDKI-GM -ENINKMSAFYGLNKTMLRRKMMDFEAV-LEGRQNTTTASEMNQLLLKMLNGELVKPKYQK -AMIKKLLACED-YTTFAAKLY-GVPIAHKTGTLDY-MRADVGIIYG--KEPLILSVFVQN -FE-SHMQAQTILADIAEIVYFQf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. KO7888 TaxID=2602737 RepID=UPI0013F612EE ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GVRADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAGPPECGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A6B1KG54_9ACTN -----LARIHAAFADAGVTGRLHAVDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGLLDLTEQVECPPDGRTAPTGIAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL -DAVNRTTARLGLTRTYAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACTPEHGA -AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSQPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga dinghuensis TaxID=1539050 RepID=A0A327W0I1_9BACT --kKLTATLQQLLKDFHGQAGIYVHHLPSGKEV-CINADTIFPTASMIKTTIQVGIFNKIA -KGELDYHQQLVYRDSLLYPGLDILGSFKDSQIDLDKVVMLMLTMSDNTASLWLQSLAGGG -TTINAWLESNGFKVLRVNSRTAGREANRKEFGWGQTSPREMARLMEMIYKGEVIDPASSE -RMYRNLTRNYWDA-QGILQVPENIRTASKNGAVDE-SRSEVIMVNAPHGD-YVYCIATKN -NANKDNEAWQLLRKVGYAIWQHy ->[subseq from] Serine hydrolase n=1 Tax=Paraflavitalea soli TaxID=2315862 RepID=A0A3B7MUE3_9BACT --rKLQQKIDELVKSQRGVAGIYVKNLRTGKVA-EYQADTIFPTASIVKVPILVGIMDKIE -KGELQYHQNLEYKDSLLYAGEDILGSFKSGEIELSKVMMLMLTMSDNTASLWLQSLAGTG -ARINQLLDSLGLQYTRVNSRTPGREDNRKQFGWGQTTPREMTTLMEKIYRGEVISHKASE -RMLRVLGRNYHDPNGI-SQVPPYIFVASKTGEVNQ-SRNETILVMAPHGA-YAYTINTKN -LEEPSNEGWVLCRKLAALLWQYy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu 3180 TaxID=2682611 RepID=UPI00135CA250 ------ARIHAAFADAGVTGRLHAVGIDSGAQL-DAGADRPVCTASVHKLCLLVTLHEHAA -AGRLDLTEQVECPPEGRAAPTGLAAMLDAARLSLRDLAFLMITVSDNTAADLLLRRV-GL -DAVNATTARLGLTRTRAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AMRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sp. 137-3 TaxID=2486021 RepID=UPI000F776524 ----------QAMGQLKGHNSVAIATSFSDDHY-QWHNQ-AQRAASDIKVFILATVYHQVD -QGKYQLSGHYTLRDADKVGGTGSLQGMAAGTVTNQQLLHYMMTVSDNTATNITLRQVGGL -GVVNRYARDLGAKDTHVVRKMMDQK-ALDAGKDNLTSVADLSMVLMKLWRHQLISTSADT -AMLKLMSENTN-HSKLPKDVPTDRTVYNKTGEFDYGVENDAAIFAK-GGKAVVVVAMSEG -GQQQVPAMNR------------- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=UPI000D0EDF4A ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -HGHFRLDDQLVLRQEDLVGGSGILYALSPGLLAIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIEQTMIDLGMRQSYYSRKLMIYPLD--ITENNKITAGDIASMLGQIATGSYLSQRACK -EMIAIMKKQQV-RNGLPSQLPNQWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Chryseobacterium sp. G0240 TaxID=2487066 RepID=A0A3N0WG60_9FLAO ----ITTDINKLIAHKKLDIGISIRNTSGDEIV-SVNSKKKYRLYSVSKFFLALYILNQVD -KGKLDLNQIITFSKKDLKPYSPLRDSIPQGALSLKKTIKYLVEESDNNVFNKLADISGGL -NHLNVFVYNTFRASKNEFFEMYDYSSSKSDFEANSITPNLATEILYQLEKKEILSNNSYR -LLKKYMEHSAI-DTRIQGIIKNDTKSFHKAGTSDREACNDIGIVNLKNGTSFMIGVFISD -SKEDDKTNDTLIAQITEIAYK-- ->[subseq from] Class A beta-lactamase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A1Y4WV00_BREBE ---ELEKRLSAIIGQAEGTWGVVVEEQGKGTRF-VHVPDELFIAESVIKVPIMAAVFAARE -QGHFRMDDQLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNILIDLV-GK -DQIDQAMIDLGMHQSCYSRKLMIYPLD--IRENNRITAGDVASMLGHLATGSFLSQRACK -EMIAIMKKQQV-RNGLPSQLPPGWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI000686D4DF -------------ADAGVTGWLHAVDVDSGAQV-GVRADQPVCTASVHKLCLLVTLHELAA -AGALDLTEQVECPPDGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEAAPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Aggregicoccus sp. 17bor-14 TaxID=2583808 RepID=UPI00129CB17F ---ALAERVRGIDLAHRGALQVWVQDVASGESY-GYDAEAPAYLSSTLKLVVALAVLREVD -AGALSLDEPLRLEAQDVRDGVGLLGPDVGTERSVGQLLELMLVRSDNTAADRLITRV-GE -DRLDSEVACRGLHFGPLRSLLTERQQAFYATGVNTAPLREVGGLLAQVARCEGLSAGSCA -RMQTLMRACRTGAARVRAGLPAQVAWAHKTGTQFQ-RACDVGFFTLAPGRSVVVAACARD -FD-QVPEAEAAFREVGAAVWS-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus brevis TaxID=1580 RepID=UPI000B34D39B -----KKDIGVTVGAIGGTNSVYVSPVNSEQSV-VVNK-GSQRSASSIKIYIMVTAYAMAK -EGVFNLNDTHTLTNDEKVGGTGVIQNMRAGTLSYREIIEYMIDDSDNTGANIMIDKLGGF -QLINNKIKSMGATDTKLRRKMLDTK-ALDNGRDNTTSARDMGTTLKMIYNHHLVSREADD -EMLAILRKNQN-RTKLPNQLPSTATVYNKTGEYDYGVQNDAEIVRNSQGA-FVAVVLSED -GEKT--DQLAAMNKLGL------ ->[subseq from] VanY domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535YIK3_9CHLR ---SLQDAVKAAVGRHQGTIGVVVTRIDSGQAF-SFNADRRFTSASLYKLFVLDAAEAAIE -AGTLDPSETLTVTSA-MAANDPYADLQVGTRTSVDCALQTMVEMSGNSAADLLLRRL-GM -STITSRMRALALNHSEIND-----NGA-------FTSPGDVAHLLASVARGEAVNVAASQ -RMLDLLGAQQH-NDRLPAPLPLNVRVAHKTGELP-GLRHDAGIVFAPSGK-YVLVAMVDD -AP-SESEARAAIVDISRSVYA-- ->[subseq from] serine hydrolase n=1 Tax=Cyanobium gracile TaxID=59930 RepID=UPI00030F1BED -----SQQWARLAAQKGLTASGFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD -RGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK -TELNSRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD -LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQMPNGQRAVLAVMVKG -PFND-PRSAELIRAMAGAVTK-- ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. GW2 TaxID=1211114 RepID=UPI0005852AFE ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA -LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPAGRDGATVVVACAE -RFGELEQAEHAFQALGRALA--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Balneola sp. TaxID=2024824 RepID=A0A3D2IC62_9BACT -----QVKILNRLVGIEGDFAISYKDINDAEKHiLINADERFHAASTMKTPVLIELYKRAE -NTDLNLEDSILIKNESIVDGSLFTYLNLNKNTTFYALAYEMITRSSNLATNILIDYL-GA -ENITNTMRDLGADSINVLRGVEDLKA-YRQGLSNSTTARDLLVIFDHLSTGTLISEKANV -EMLKILKDQVY-NDMISAKLPKGTPVAHKTGWITN-VHHDSGIVFTGNNEGYILVFLSKN -APDRD------------------ ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas sp. J31 TaxID=935851 RepID=UPI00048F8CB8 ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALADALGVPRAELDTTLEQVFEDYYARGLNSATLPAYGRLLERLASGELLSPRSTA -LLLGHMRAISTGSRRIQAGLPAGADFAQKTGTQQQ-RACNVGLLDPAGRDGATVVVACAE -RFGELEQAEHAFQALGRALA--- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. UNC363MFTsu5.1 TaxID=1449069 RepID=UPI000483D817 -------------------------RVDDGDAV-SVEADDLVVTASVYKLPLLVALCREFD -TGALSPTATVRVNPADCTPPTGVSIFRDPVVMSWRDLALSMMTVSDNAAADLILGSV-GL -DGIDRVLTELGLRRTRIIGGTADVHRAYDPAFTSATTPREMTSLLDAIWTGRAVSAAQTE -FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAVFTRA -ARADLPVVDQAIGRAAHIAVT-- ->[subseq from] Serine hydrolase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A3R9T0D6_9ACTN -----AGRLHAAFADAGVTGLLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA -AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLTALWRDEACPPQYGA -AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase (Fragment) n=2 Tax=Subtercola sp. Z020 TaxID=2080582 RepID=A0A2S5VZK4_9MICO ----ISAELASLESTSAARIGVSAVDTATGRTI-AYRADERFGYASTIKVFAASLLLQTTP ---PEDRARLANWTQSDVDAHSPATGEHVADGLSLAQLAEAAVRQSDNTALNVLLANLGGP -QALDAALTQLGDDTSDVVDVEPALNTVEPGSTANTTTPAAFTADLRALLN---------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. H3C3 TaxID=2530368 RepID=A0A4R5BUM5_9ACTN -------RIEAAFRDAGVTGHLHAVDVDTGREV-AVRAEEPVVLASVFKVPLLVAFHRQAA -AGTLDPTERVTLRPQDRTSGPTGLSALLDEVMSLRDLACLMITVSDNASADALLERV-GL -DAVNATAAALGLPGTVVEGGGRDLFDALDPALTSRSTPRDMTRLLGLIWRDEAAPPPECA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -PLAVLPEADAVIGAAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nibribacter sp. BT10 TaxID=2698458 RepID=UPI001366EB34 --qKLTQKLEALTKGFEGEVGIYVKHLKTGKTV-AINADTLFPTASMIKVPIMVGVFNKIE -RGELDPKAILQYRDSLYYAGEDIVGNFKDSSVALSKVQMLSITTSDNTGSLWLQQLAGTG -TAINQWLESNGFVHTRMNSRTPNRRPNWERYGWGQTTPREMATLLTTIREGKAVSPAASE -RMYRNLGRIYY-DSEALSQIPPYVHTASKSGAVNQ-SKSEVVLVNAPHGD-YVFCIITKN -QKDEDNAGSVLIRNVSKILWQHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NEAU-D10 TaxID=2293571 RepID=A0A371Q1R5_9ACTN ---DTAARIHAAFAEAGGTGWLHALDIDSGAQI-DAGADQPVCTASVHKLCLLVTLHELAA -SGSLDLGEQIECPPAGRTAGPTGLAAMLDPVISVRDVAYLMMAVSDNAAADLLLRHV-GL -DAVNRAMTRLGLTRTHAVHTFGELFAALDPARTNRSTPRDMTRLLGAVWRDEACTPEHGA -AIRRILGLQVW-PHRMASGFPDDVHVAGKTGTLPT-VRNEVGVIEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. CYP1-5 TaxID=2604572 RepID=A0A5D3FM37_9ACTN ----ITERIEDEFKAAGVTGWLHAVDVDTGREV-SVRADEPVVLASVFKVPLLVAFHRQAA -SGVLDPSEQVALRAEDRTAPTGVSGMLDDVRMSLRDLAFLMITVSDNAAADVVLDRV-GR -DAVNATAEALGLPGTVVEVSGRELHGVLDPLRTSRSTPREMTRLLSLIWRDEAASPEGCA -AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LLAVLPQADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacillus porteri TaxID=2126350 RepID=UPI000D0E606B ---ELEIRLSAIIGQAEGTWGVVVEEQGKGTRF-EHVPDELFIAESVIKVPIMAAVFAASE -QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AKIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGQIATGSYLSERACK -EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. CZ-2 TaxID=2557994 RepID=A0A4P7DYC5_9SPHI --kKLTAKIQQEINGFRGDIGIYVKNLKSKKEV-RISSDSIFPTASIVKVPLLVGIFQKID -ANEVQLDQKFIYSDKRTYGGSGLMQFYKDSATDLSTMISLMLTYSDNVTSIWIQELAGGG -QTINPLMDNLGLKNTKVNSRTAGREDIWKKYGWGQTTPYEIAHLFELIRDGKVISEKHSD -KMYRFLKNQFY-NERSLSQIPAIYATISKTGSVND-ARGEVVLVNAPHGD-IVFSILTKN -NKTKDNEAENLTRRIAKIIWDHf ->[subseq from] serine hydrolase n=1 Tax=Pseudoclavibacter caeni TaxID=908846 RepID=UPI0013012D89 --------------------------------------GGRVAAASTIKVALAAYVLDGVD -RGSWTLQTPVTVPADDVVGGSGTLGGQAAGRYPLEQLLRLMITVSDNTAANALIDLVGGF -DPVNAWLVEHGFDELHLGRKMILPHAA---DAENWISADQAVRLLAAIHDHTLVSVESSE -RLIDLMRDQTV-RTKLGAVIPHD-LLADKTGENT-GVSHDIGYLLVPGRT-VAIAVLTGY -DGAGADAANSTVQRAGAAVL--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0005C729BE -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A2C1I0R7_BACME -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNKVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. IHB B 7164 TaxID=1827146 RepID=UPI0007CDABCE -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGSDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus enclensis TaxID=1049584 RepID=A0A1C4FVS2_9NOCA ---SAQQVIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] CfxA family class A broad-spectrum beta-lactamase n=1 Tax=Candidatus Amulumruptor caecigallinarius TaxID=2109911 RepID=A0A4Q0U8U3_9BACT ----LKERIDSIIKEKPGKFGVALI-VDNRDTV-TVNNTDDYPLMSMFKLHEALGVCHVMD -SLGRGLDSVMVISREHLDPYSPMLKEYDMPELSVGRLIDYILVDSDNNASNWLFDSIVPV -SYVNSYIGTIPEQSFEIVWRESDMAAEHSRAYDNRSTPLAYASLVNRVFTDSIVSRDKQE -HIKSAMLRCDTGMSRLAAPLEEGVTFGHRTGSGYVNAVNDGGYVTLPSGKSYAIAVLVKD -YAGPQEDAEAVMAAISKAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000476C1CC -------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELITLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRK -KIMRMLEMQQF-QHKLPACIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI00131F6ACD ----LEYKIREIMVRSKGRVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ -EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS -NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRW -KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELS-GVEHDCAIIKYREKT-AYIAVLIDG -LGET-ESGKDTIAQIGKLIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536C911_9CHLR ---ELVQHLDQLVSSFPGGAGLWIADPNAAKPLySHDADEPVITASLYKLAVLAEAERRVD -AGQLHYGDVITIESEDITEDGSF--EVAGTELTLDQALEAMITISDNGAALALWHVL-GA -DNINATLRNVGINDFHVFVA--------WGEDANVATPRAIGTLLTLLAKRQLISAAASD -RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD -AY--DADAYAFIANVGSIVYS-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus acanthi TaxID=2171554 RepID=UPI000D3EBCF3 ---ELTARLNSEIKNCPGKMSVMLEV---GQHCfQWDPHRKVPSASLIKLPILLEGFRQIE -NGTLNLYDAIQIQEYQKVEGAGVIHKLSNAKLTVQDLLTLMIIVSDNTATNVLIDLL-GM -EKINSFIKEQGCNSTELNRKMMDFDSII-KGINNWTTASEMVLMLKEIDIGLGYSSNSKE -LMKGILQNQQF-LDKLPLDLEDGW-IGNKTGELS-GVEHDCAIMKKGNKS-AYITVLCDS -LP-SKGVGKIAIAKIGSLVWEY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012939A40 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNAVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGVDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLKMQQF-QHKLPARIGSAFQAVNKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2D8LF37_9CHLR ---KLVKSINTQVENFNGVAGVSIKDLTTGWYY-GINDEMIFPTASSIKIPILLKLIESSE -ASKLNLLKNIEITEEMKSRGSGVIHKMNGTILTVENLAILMINLSDNTATNLCIDIA-GQ -DEVNKMLEDYEFVSMRLNRKMQDYT-AIKEGRENLSSVKEMNLILEMLDSSRAIKPDVAK -KVLNILSLNKS--TPISQPLPENIIVAGKTGGMP-GVRCETAIIYLTNRK-YILTVMTSH -AGNGSSSSNQNIG---------- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus enclensis TaxID=1049584 RepID=A0A2A5JG58_9NOCA ---SAQQEIAAVLAEAKTDAYVHERDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. p1417 TaxID=2681492 RepID=UPI0012F672A2 ------TRLKEAFAEAGVTGRLHALDIDSGAEL-GTGADHPVVTASVHKLCVLITLYEQAA -AGLLDLTEQVECPPDGRASGPTGLSAMLDPVMSLRDAAYLMIAVSDNTAAELCLSRV-GL -DAVNATTARLGLTRTRALHTFRAMFEALDPARSNHSTARDMTRLLRALWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ARATLPPADAVIGTTARIAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645BKY1_9ZZZZ -------KIGAMRFSLPGKSAVAAVNLVTGDAF-SWNGDEIFPSASIIKLPILCTAYAMAE -SGELSLSDRIEVTDAAKTGGDGVMRLMQPGLPTLHDLMTLMIILSDNMATNMVVDAV-TP -QRIHEFLESRGLTRIRWRRKMMDAA-AMAAGIENEAAAGDVTELLKGLAMGTLLSPAHCR -DALDILSRQQI-NHKLPRRLWEEIKIAHKTGDIP-GLEHDAGVFTGPGF-SFVLTVMTLG -PREPQQKQWDFIGAVAEEFVRYw ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A6B3R733_BACME -------------------NGLIRIHIEGKESI-QVNSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Symbiobacterium thermophilum TaxID=2734 RepID=UPI00130DCC32 ----VVRRIERLTRWAPGVVSVWYYDLSTHETF-GVRADEVYTAASTVKVLIANYLYHLAA -TGQVSLDEPLAIRAVDWKDGSGILNGVPDGTLPLREVARLMLVHSDNTAANALMRRL-GV -QPMVQYYRSLGIR-----YGTPRMHTPGELWEGNRIAPEDLGIVLRNIWEAARRSPEPWE -ELLGFMRESRS-KGRIPAGLPSHVPMANKTGSKGT-SFHDAALVL--DRRPYVLVVMTQG -MT--ARQASHYIAAVSREVWE-- ->[subseq from] Beta-lactamase, putative n=2 Tax=Deinococcus radiodurans TaxID=1299 RepID=Q9RX82_DEIRA --------------GYAGEVGLLVTDFAGRELY-AQAADAVFPAASTIKVPLLLFALEQAG -RGDLDLIERVTLRAEDRVPGAGVLHELGLGLLTWQDVLTLMIVVSDNTATNLLIERL-GQ -DHFNLWLTARGLNSTRLIGPLERQNEAQRRGERNRTTARDQVALLLSLLRGDGLTPQMQH -LALDILSRQHL-RDLIGRGVPAGYRVASKSGELR-GVHHDVGLLWAP--RPLVVALLSQG -GEDPR------------------ ->[subseq from] serine hydrolase n=1 Tax=Acidobacterium ailaaui TaxID=1382359 RepID=UPI000678C694 --tALEAQLRGLTALHRGKVAIFAKDLNSGRTV-AIQADTPVPTASVIKLTVLFEALKQVQ -AGKAHFEDRLRLTKDNQVEGSGVLSFFDTPQLTLKDVLTMMIIVSDNTATNMAIDKL-GL -KKIDDRIQWLGLKDTWLYRKVSKPASDQKQFGLGKTTAREMAAVMERFATGETAPPTKDQ -QVAMHMLRNQFYRNSIPRYLEGESKIANKTGALDH-VRNDVGVVDAKNG-PVIISEFTWD -NQTPDNSAEVLMAKAAKIIVDRw ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. BS56D TaxID=2055944 RepID=A0A4R0R5S0_9SYNE ---ALSQRWQELAAQKDLQVSAFLLLLDDGRYA-QLNPDTALPAASSIKTPILLVALELLD -AGTLSWNEPLTLTKTTVGGGAGWMASPIGTRFPTHEVATEMIRVSDNSATNLLIERVGGK -EELNARFNALGLSATAVNNWLPDLEGT------NTTSARDLARSIALVDTGETLGPRSRD -LFREVMGTSRT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFVVKG -PF-NDPRSTELIREMAAAM---- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Bacillus TaxID=185979 RepID=A0A231RCC0_9BACI ----LEYKIREIMVRSKGRVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ -EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS -NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRG -KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKYREKT-AYIAVLIDG -LGET-ESGKDTIAQIGKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI000551775D ----LEYKIREIMVRSKGRVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ -EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS -NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRG -KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKYREKT-AYIAVLIDG -LGET-ESGKDTIAQIGKLIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E5I681_9BACT ----------------AGEIAVAMSTLDGDTYF-FYKEKKVFHAASTMKTAVMLELYRMRD -RSELSLKDSLLVVNQSIVDGSTYSMARLGEKMSLKDLNEAMITTSSNLATNILLNMV-KP -EQVMKTVSEVGAEGVLVLRGLEDLK-AYERGLSNRTDAHGMMMLMRAVVESPVVSDDSRD -AMLRILGRQEF-NEMIPVGLPAGTEVAHKTGRITS-ICHDAAIVFPPLQEPFILVILTRG -FEN-HAQATAAGVAVTKSVYSYy ->[subseq from] Serine hydrolase n=1 Tax=Lacrimispora algidixylanolytica TaxID=94868 RepID=A0A419T6S4_9FIRM --------------PLPGKISFYFENLDTGESI-GYREHETMMAASVIKLFVMVSVFEGVE -RNSFPLDKMFEIKREECVPCGALTYLHEQIQVTLMDLVTLMIIFSDNTATNVLIDFI-GF -DVINRTIVELGFERTVLNRKMFDLVSS-KLGIQNYITAGEIGKLLKMMFEGTLVSRRASD -TMLSIMKNQQL-AGKIPFYLKERLEIAHKTGEDI-GISHDVGIIYGK--VPFIVC-FCGN -ET-DTPRLERLMADISLELYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium wenxiniae TaxID=683125 RepID=A0A1I6Q2R2_9SPHI ---KLENLLLEQVKDFQGDIGIYVYHSKKNTSV-AINADTIYPTASIVKVPILVGVFNKIN -QGELKLSDSYRYDAKRAYGGSGLMQFYKDSATDLSTMVSLMLTYSDNVTSIWCQELSGGG -ATINQLMDELGLPNTKVNSRTEGREEIWKKYGWGQTTPREIVELMRLIREGKALNPRLSD -KMYRYLKNQFY-NGRSLSQIPAHIATASKTGSVDD-ARGEVVVVHAPSGD-YMFSVLTKN -NKTDTNEAEELTRKISHLLWDYf ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus agglutinans TaxID=1644129 RepID=A0A438BE72_9NOCA --------FEGLFADAGVRGWVHAVPVAGPDTEaGRDPDTPVVMASVYKLPVMVTFCRSVD -AGHLDPTEQVTLAPENRTPPTGVSQFLDPVRISLRDAVRSMMAVSDNAAADEVLRRV-GV -DRVNETMRTLGLGSTRVLGGTADTLRGYDPVLSSATTPRDMTTLLSAVWSGAAASPEQTA -FMRTVMSSQVF-TARLRSGFPGDVVVAGKTGTLG-AIRNEVGVIEFPDGDAFAVAVFTRA -ARADLPSADAAIGRAARAAIA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. T12 TaxID=477697 RepID=A0A560WEN1_9ACTN -----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA -RGELDLTEQMETVPGDRTTPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLSRV-GL -DAVNAATARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEAGLPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=2 Tax=Lacrimispora celerecrescens TaxID=29354 RepID=A0A084JR07_9FIRM -------EIIEKLEQLPGRISFLYENLKTGDGF-AYHEQEPMMAASVIKLFIMAAAFEKSK -KGTFQMEELFAVKKEDCVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM -EEINETIQGLGFERTILQRKMYDMVRS-AQGIQNYITAYETGRLLKMMYDGTLIDSQSSD -TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEIS------- ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E0BAN4_9BACT ---DLEERILKILKTEKGDFAIAFKNLSDGKSI-LINENEEFHAASTMKTPVMIEVFKKAQ -KGIISLDDSIKIKNESIADGSTFKYDKIGSYLSLRELVFDMITISSNFATNLVIDYI-GX -XDINNTMRDLGAKNINVLRGVEXIXA-FXQGMNXTTTALDLLKIYEXLAVGNVINSEXSK -EMVXXXKKQKY-DDIIPKYLPKSIEVAHKDGWIX-GVRHDSGIVFLXDNTXYXLVLLSKN -LE-DEIKGADLLAKVSLEIYN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces capillispiralis TaxID=68182 RepID=A0A561TGU3_9ACTN -----LARIHAAFADAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCVLVALHEQAA -AGMLDLTEQVECPPAGRTTPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLRRV-GL -DAVNATTTRLGLTRTRAVHSFGQMLAALDPARTNRSTPRDMTRLLGAVWRDEAGTPEHGG -AMRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Cyanobium sp. CACIAM 14 TaxID=1496688 RepID=A0A081GJ59_9CYAN ---------SRLAAQKDLTASGFLLVLDDGRFA-QMQPDRPLPAASSIKVPILLASLEDLD -EGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK -ASLNSRFRSLGLPATVVNNWLPDLDGT------NTTSSRDLARAIALVDTGDKLTPRARD -LFRQIMATSRT-NTLIPLGLPEGITVYNKTGDIGI-AYADAALIELPNGQRAVAAFMVKG -PFND-PRSAELIRAMAGTVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Ruminococcaceae bacterium D5 TaxID=1520815 RepID=A0A1I3MWM7_9FIRM -------AIRDYTEPFAEKIGLVVHDVRTGAVF-SRNPDRVFPSASVIKLAILWEFYRRVA -EGSLNPEEPYVLHDDVKEGDTGILRDFHDGLLTLQDIVTMMIVISDDTATNILIDRF-GK -EAINESMSRIGLTHTRVQRRMMEYDKV-RAGIDNEISAGDMDRYFTLLLAQDSMPAGCRE -TMLDILARQRY-TAAIPSLLSEDTRIAHKTGTIGFGLEHDVGLIYGPDGRPAVIVAALTQ -HL---ENRLHVIGTIAKMALE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacterium sp. SSI9 TaxID=2605433 RepID=A0A5D4GYB7_9SPHI ---KLERILQNEIKDFQGDIGIFVQHLRQNKTV-DIQADSIFPTASIVKIPILAGVFNKIN -LGELKLNSPYLYDAKRVYGGSGLMQFYKDSTTDLSTMVSLMLTYSDNVASIWCQELAGGG -TSINRMMDDLGLPHTKVNSRTEGREEIWKKYGWGQTTPREIAQLMTLIQQGKVITPRLSD -KMYRYLKNQFY-NERSLSQFPAYIATASKTGSVNE-ARGEVVFVHAPSGD-FVFAVLTKN -NTTRDNEAEILTRRIANILWNYf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. ALD TaxID=2293318 RepID=A0A371TKN3_9BACI -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bradyrhizobiaceae bacterium TaxID=2072420 RepID=A0A431RGS3_9BRAD ------------------------------------------------------------- ------------------------------------------------------------- ------FWRSLGDSTSRLDHNEPELNRSPPGNPQDTTAPAAMAGNLRRLVLGEALTPASRT -LLTEWMVNCKTGANRLRGGLPASWTVGDKTGNNGKDASGDIAVVWPKPDTPILITAYVQG -GTPNAAQIEAVFARIGRMVTE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. SMB37 TaxID=2512213 RepID=A0A4V2RKN6_9NOCA -----TDRIRAVFADAGCSGWLHARRCSDDEATlSVHGEERVVLASVYKLPLFLAFCAEVD -AGRIDPRSELRIEPSECTPGSGIATMRDPVTMSRRDIAASMMIVSDNAAADVLLGEI-GT -VAVHDMLARLGLEHTNIVGGTADMYRAYDPAFTSATTAEEMTRLLATVWAGDVLSAEQTG -FVRHVMRSQIW-PHRIAAAFPRGVSVAGKTGTIGI-IRNEVAVVEFPGEHPVAVAVFTRA -ARPSLPLVDAAIGEAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. HMWF019 TaxID=2056856 RepID=A0A2R7KEP2_9SPHI --pKLEQRLQQLVKGFNGDVGIYVKNLKTGRSA-GISADSIFPTASMVKLAITAGVFNQID -KGQLDYKSVLTYKDSLLYAGEDILGSFKNGEIALSKVLMLMITTSDNTASLWAQSLAGTG -TAINDLMAQYGLTYTRVNSRTPGRQENQKKYGWGQTTPKEMATLLTLIRNGKLINEAASE -RIYRNLIRIYF-DQEALSQIPPYIQAASKSGAVDE-ARSEVVLVNAPHGD-YVFCITTKN -QKTPSNEGWVLIRKLSRMLWHYy ->[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. R11 TaxID=2695265 RepID=UPI001413126E --kKLTKQLEEAVKGFNGDIGIYVHNLKTGKTA-AFNADSIFPTASMVKTAIQCGVMDKIE -KGELQYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVAMLMITMSDNTASLWLQKLV-GG -DYINNWLQQNGFNVFRVNSRVPGREAFRKKYGWGMSSPYEMCKLFTMINDGQAVSPAASE -RMMRNLTRIYW-DERALSAIPPYIHTASKQGAVNE-AKSETVLVNAPHGD-YVFSVMTNN -IKTTDNEAEMLITKISTVLWHYy ->[subseq from] Membrane alanyl aminopeptidase n=1 Tax=Haliscomenobacter hydrossis (strain ATCC 27775 / DSM 1100 / LMG 10767 / O) TaxID=760192 RepID=F4KQF2_HALH1 ---ELEAAIKAELARVEGTFYVAFRDLQNPVQAvFINEKISIHPASTMKTPVLVEVFKQAN -QGKFKLSDSIVLKNESIVDGSPYSYQRMGQKVSIYDLARAMIVRSSNLATNMLIELV-GA -ENTTQTMRDLGLQDIMVRRGVEDSK-AYAAGLNNSATAYDLMLLMERIGRGEAGRPVDCQ -EMIKILSDQEF-NDVIPTCLPADVQIAHKTGWITQ-HHHDSALIISPEGRYFSFTILSKG -WT-NETAANEAMGKVVEMAYRYf ->[subseq from] Serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=A0A415DUX8_9FIRM ------------LKNCTGKVGFYYKNLITKEEL-AYQENESFIAASIIKLPIFAQVIKVSS -EHRLDLGKEVQIRKEDILPSCGAINLFSSEPLDLRTICNFMIALSDNTATNIMIREC-GI -AALNAGFQEMGLMKTRLERPLFDET-ASMAGKDNYFTPAEIAMLLESLYEERFVSSAVSK -DILQTLKMQNI-NYKIPGLMAERFEVAHKTGEDD-GITHDAGIVYCD--QPFIIVFASNG -TD--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 3211.1 TaxID=1938843 RepID=A0A397R2Q0_9ACTN -----LRRIAAAFAEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQHAA -AGRLDLTEQVECPPDDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DGVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTTARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A1I0I6C9_9FIRM --------IIKKLERIPGKISFLYEDLKTGEGF-AYHEQEPMMAASVIKLFVMAAAFEKSK -KGTFQMDKLFPVKREDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNILIDIL-GI -EEINDTIQGLGFRHTLLQRKMYDIKRS-SRGIQNYITAYETGRLLKMMYEGTLIDRRSSE -AMISILKNQQL-CSKIPFYLQESPEIAHKTGEDT-GITHDVGIIYGK--EPFL-VCFCGN -ET-DTPAFERVMAEVSLELYK-- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter certesii TaxID=228955 RepID=UPI0003F56093 --kSLEKGLRELVSDFKGDVGVYVYNLTTNTVA-AINADTIFPTASIVKVPILIGVFDKIH -KGALSLNDTLVYDDKRAYGGAGLMQFYKDSTTDLRTLISLMITMSDNTTSLWCQELAGGG -ETINALMANLGLKHTRVNSRTEGRTKDWDKYGWGQTTPKEMAFLLTKIRNRKMINAASSD -EMYRVMSNSFYTDYSL-SQIPPYIQTAAKQGMVNT-SRSELVMVNAPTGD-YVFYIGTKN -NKDADNEAWQLQRKISAYLWNYf ->[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T13 TaxID=2696565 RepID=UPI001411FED9 -----------------TRAAVWAVDLRSGRRL-DHDGHHQRPLLTLSAGLAAAQLLRTAT -----PLTRRVRYGADDVVPGSPVAGSHVREGMSVAQLCTAALGRGDDTAANLLLQLSGGP -LGLTRFCRSLGDGTTRVDRWAPESASGEPWDPRDSTTARALARDYGVVLLGPALPAASRL -QLRSWLP---T------ALLAGGWSFSHVTATGWYGTAGAVGIARRGTR-QVVIASLVRG -ADASAPGT--------------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BED8A99 -------------------NGLVRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKEIDNYTCASDVVKCLREIYEGNLLQKSSRG -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNAQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. alain-838 TaxID=2026340 RepID=A0A269TPC7_9ACTN -----AGRLHAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA -AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFAEMLGALDPARTNRSTPRDMTRLLSALWRDEACPSEYGA -AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=bacterium JKG1 TaxID=1128421 RepID=UPI00047862D9 -------ALERWLAAQPGEYSVCVVR--DGAQVyGYREHVPRSAASLIKVPLALAVLDA-- ---GLDLEQRVLLREADRVAGCGSLDAAPAGTATLRQLIVHALVESDNTAANLLIARL-GM -PAVNRWLAEHGLTQTRLRRRFMDLDA-LRAGCDNTTSAAEMCAILALLL------DPRRC -WLLELLRQVAD-DDKLGAGLPPGTPLAHKVGDLP-GVEHDAGIVWTPGG-PLIMAALACA -LP-DAATGRAAIRHIARVVWR-- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. 774 TaxID=2172652 RepID=A0A2T9K2J4_9CAUL ----MSLKLTAIAERAPSDLGVAVQDLTTAQRA-TVAGEHLFPLAGMWTAALGAAVLAEVE -AKALSLRETLTVEDVDLSPPSEVADAWPGRRWTVEELLKRAVAGGDNTAADVLMKRIGGP -GAVTAWLDLKKVENLRIDRYARQLLPDYLVDPRDSTTPLAAVRFLEALNQGELTDQDGRR -RMLRMMEAAA--GDRLRPALPAGARLAAITSATPTAADNVLAMVRLKDGRRFALAIFLKA -SPMEEADRDAVMLDVMRTILQ-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-2747 TaxID=1463843 RepID=UPI0004C850E1 -------------AEAGVSGRLHAVDIDTGTEI-DAGADHPVVTASVHKLCLLVALHQQAA -AGLLDLTEQVECPPDDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DGVNEATARLGLTRTRAVHTFRSLFAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTTARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium SCN 70-22 TaxID=1660163 RepID=A0A1E4B5V9_9BACT ---ALRRALDALADAHHGVVGYAVRDIDAGATI-SRRGDETFPTASLIKVPILVTVYDLVA -RGMLSLDDRLTVLGIDKVPGSGTLQFHDGIEVTVRDAAWLMTTISDNTATNILLDRI-II -RRVWDKMEALGLEHTKVHSKTFLRSSSVAMDSSGVTTPNEMARLFELLARGEAVSPSADS -AMLDVLAHNED--NVLLQRYADGVRAAHKTGATD-AVRTECSLFYLTRR--VVACVLTRE -NADQDAEPQLTMARMGEAIVRAw ->[subseq from] serine hydrolase n=1 Tax=Lentzea aerocolonigenes TaxID=68170 RepID=UPI0004C43C63 ------------------------VGVENGPEV-CHQADDQVVLASVFKIPVAVAYAAEVA -AGRLDETERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ -AAVDEVLANLGLHRTRIMGCCEDLFAIVDPARTTSSTPREITTLLDAIWTDRAAAPEACE -QVRRIMAQQIW-PHRLGSGFPSDVQIAAKTGTLPS-VRNEAGVVTYPDGRSYAVAVFTRA -QAPRQPAVDAVIGRAGRLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=A0A3D2P0H7_9CLOT -------KIDELINRLDGEASVLVKNLSTNEVY-KYDENKIFPSASMIKVPILLELIDRSC -ERKINLDDVVEFKKEDIVQGYGIIKSSPGINMTYRDCALLMIILSDNIATNKLIETL-GM -DSINEKIREIGMENTILQRKMMDAEA-KKKGLDNFISGADLLTIFEYLYS-----HEKYN -IAVDILKKQLC-NDLLPVLIGGNIEFAHKTGDLP-GVRHDSGIMYLK--SPIFIAVLTNN -LKND-CDGITFSNEIGKIVYDHy ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0013F464E5 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIETFRQID -AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Beta-lactamase n=4 Tax=Bacillus TaxID=1386 RepID=A0A0M0WJF0_9BACI -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Alain-F2R5 TaxID=2026341 RepID=A0A270QWX7_9ACTN -----AGRLHAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA -AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFAEMLGALDPARTNRSTPRDMTRLLSALWRDEACPSEYGA -AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Microtetraspora fusca TaxID=1997 RepID=UPI00082A549E --------LKEVFDDADVEGFVHVRDVDGSAEI-GLNPDEPVVLASVFKIPVVLEYARQAA -AGTLERTERLTVTAADKDGGIGTSGCADDISLTLRDLAHFMMTMSDNAATDVLLRRV-GL -ENLHATLRGLGLGRTRLVGGCAELLGVLDPERTTSGTPRETTTLLSKIWRDEAGPAEACA -EVRKIMGNQIW-PHRLSSGFGDEVKVSGKTGTLP-GVRNEAGVVEYPDGRRYAAAVFLRT -DSLRLPQADAAIGRAARMAID-- ->[subseq from] serine hydrolase n=1 Tax=Salegentibacter sp. Hel_I_6 TaxID=1250278 RepID=UPI00056248C1 ---ELQQKLEQLTQTFNGDVGVYVKNLKTGKEA-AINADTIFPTASIVKVPILLKIFDKID -KGELKYNDTLVYSEDRIYGGSGLMQFYKDSATDVRTLVALMISYSDNVTSLWNQELAGGG -EAINELLAELDLEHTRVNSRTEGREKDWEKYGWGQTTPREMAIILEKIRKRELISAAASD -EMYRLLGNSFY-QEYALSQIPPYVQAAAKQGMVNK-SRSELFMVNAASGD-YVCYIATKN -IEDDNNEAWELQRKISALLWSYf ->[subseq from] Putative beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67LM9_SYMTH ----VVRRIERLTRWAPGVVSVWYYDLSTHETF-GVRADEVYTAASTVKVLIANYLYHLAA -TGQVSLDEPLAIRAVDWKDGSGILNGVPDGTLPLREVARLMLVHSDNTAANALMRRL-GV -QPMVQYYRSLGIR-----YGTPRMHTPGELWEGNRIAPEDLGIVLRNIWEAARRSPEPWE -ELLGFMRESRS-KGRIPAGLPSHVPMANKTGSKGT-SFHDAALVL--DRRPYVLVVMTQG -MT--ARQASHYIAAVSREVWE-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. BO 8801 TaxID=169670 RepID=UPI000B9888D3 -----SQQWARLAAAQGLTASAFLLVLDDGRFA-QLQPDLPLSAASSIKVPILLASLEDLD -GGKLRWNEPMPLTKEVVGGGAGWMANPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK -TNLNTRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD -LFREIMATSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDAALIQLPNGQRAVLALMVKG -PFND-PRSAELIRAMAGAVTK-- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI0012FF2731 --eELTAQTVRIIGDTKNQMAVYFLRPDREIEP-FVYNSQQMAPASMIKLFVMAKTMQDVH -DGKLSLEEKITIKKSDAVGGAGVTTWYDAGERTIQQLMTVMITDSDNTATNILIDRL-GM -QNINQYLQQQGFNDTVLVYKMMMGR---KGKKKNLSSARDIGKLLSRLYYHQLVGEQEDE -LMRDILCQQHD-KECFPAALP-DYEIAHKTGEVND-VYVDGGIFFGQKED-FVLVVLSNG -KAGR------------------- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus geothermalis TaxID=68909 RepID=UPI0002F17F48 --------------GYVGEVGVLITDLAGRELY-ALNPDRVFPAASTIKVPLLLLALSEAQ -AGRLDLSGRVTLRAEDRVPGAGVLHELMPGLPTWQDLLTLMIVVSDNTATNLVIERL-GL -DRVNDWLGERGLSGTQLVGPLERQNAAQRRGERNRTTARDQVALLGALVRGELLDRSHTG -LALSILERQQL-REILGRHVPCDYRVASKSGELM-GIHHDVGVLFTP--RPLIAAVLSQG -GL--------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004BD7A56 ---SVAARLDAAFADAGVTGWLHAVDVDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. MW101C3 TaxID=210768 RepID=UPI000B9825E4 ----LSARWKALAAQKDLKVGGFLLVLDDGRFA-QLNPDTPLPAASSIKTPILLAALEDLD -RGKLRWGEPLPLTKEVVGGGAGWMANRPGTRFPFYEAATEMIRVSDNSATNLLIKRVGGK -LAINARFQALGLPATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGAKLSPRARD -HFRTILGTSRT-NTLLPAGVLKGITVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG -PFND-PRSTDLIRAMAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus maanshanensis TaxID=183556 RepID=A0A1H7TP82_9NOCA -------------------------RVDDGDAV-SVEADDLVVTASVYKLPLLVALCREFD -TGALSPTATVRVNPADCTPPTGVSIFRDPVVMSWRDLALSMMTVSDNAAADLILGSV-GL -DGIDRVLTELGLSRTRIIGGTADVHRAYDPAFASATTPREMTSLLDAIWTGRAVSAAQTE -FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAVFTRA -ARADLPVVDQAIGRAAHIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Cytophagaceae bacterium SJW1-29 TaxID=2654236 RepID=UPI00128D0EFA --kALTRQVAEAVKGFNGEVGVYIRNLRTNRTV-EINADTLFPTASMIKVPILCGVFDKLE -KGELRYDQVLTYRDSLHYDDGVVGSLRDSAQIPLSYVLMLMETLSDNTGSLWMQALAGGG -TSINQWMEKQGFQKTRVNSRTPGRQEAQKTYGWGQTTPREMAELVVMIRAGKAVSPAASE -RMYRLLGRQFW-DGYALSQIPPTIQVIAKNGAVDQ-AKSEVVLVHAPHGE-YVFCITTKN -QTQPDNEGYMLLRKVSRLIWNHy ->[subseq from] serine hydrolase n=1 Tax=Arenibacter latericius TaxID=86104 RepID=UPI0004145123 ----LESGLKDIVSDFKGDVGVYVYNLKTNSEA-AINADTIFPTASIVKVPILTGVFDKIN -KGELSLNDTLIYDTKRAYGGAGLMQFYKDSTTDLRTLISLMITMSDNTTSLWCQELAGGG -ETINALMANLGLKHTRVNSRTEGRTKDWEKYGWGQTTPREMASLLTKIRNRQLVNAASSD -EMYRVMSNSFYTDYSL-SQIPPYIQTAAKQGMVNQ-SRSELVLVNAPTGD-YVFYIGTKN -NEDVDNEAWQLQRKISSYLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=A0A5P1YD78_STRTE -----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA -RGELDLTEQVETVPGDRTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLSRV-GL -DAVNTATARLGLTRTLAVHSFGEMLAALDPARTNRSTPRDMTRLLGAVWRDEAGLPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI00061B83FF ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSDFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia concava TaxID=257281 RepID=UPI000592E100 ------------FRTAGVEGRVHARCFDCDGEF-GWNADEPVVLSSVVKVPLVLEFARQVA -AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAACLALTISDNTAADLLFDRV-GV -ENVRSLVRELGLTRTRVEGSIRDILYAVDPLRTTAGTARDMTRLLRLIGRDEAGAPEACA -WVRDLMRQQAF-GHRLPSGFPPGVDIWSKTGTLP-GIRNDIGVVGYPDGSRYAIAVFTVS -HSGRQPAVDRAIGEAARLAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus faecimaris TaxID=686796 RepID=A0A1G6N8J1_9BACT ---SLQQKLDLLSADFKGELGVYVEHLSNGESA-QLNADSIFPTASIVKIPILLGIFDKIE -KEELHYHQSLIYRDSIKYGGSGLMQFFQDSTTDLRTLIALMLSYSDNTASLWLQTLAGGG -ETINPLLEKWGYLHTRVNSRTQGRAKNWENYGWGQTSPREMANLLRKIHEGSLFGPAYSE -QMSRLLSNSFY-TEYALSQIPPTVNVLSKQGMVN-ASRSEVLLANAPKGD-YVLAIFTKN -NEDETNEAWSLSRKISNMVWDHf ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 1001175st1 A10 TaxID=2559709 RepID=UPI0011063B05 ----IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEPFETASTIKTYILACLFDQVE -KGKASLEDMVEFKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA -KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK -FSDAAHPATVFGARVSRLLFDQf ->[subseq from] Serine hydrolase n=1 Tax=Chryseolinea soli TaxID=2321403 RepID=A0A385SPX9_9BACT ----LTGKLQETLQGFKGVAGVYVRNLRTGKTV-TINADTLFPTASMIKIPITIGMFDRID -RGEIDYHTLLTYKDSLLYEGEDILGSFKNGEIALSKVMMLMITTSDNTASLWCQSLAGTG -TAINAWLEKNGFENTRVNSRTPGREANRTRYGWGQTTPREMAELVTRIRDGKVISPRASE -RIYRNMIRIYW-DSESLSQIPPYIQAASKQGAVDQ-SRSEVVLVNAPHGD-YVFCVITKN -QETPANEGYVLLRKVSRLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A519WTJ9_9SPHI ---KLNAMVADLAKDFKGDVGIYVKSLKTGKVA-SFNADTIFPTASMIKVPITCGIFDKIE -KGELEYKTQLIYKDSLLYAGEDILGSFKHGEIWLAKVLMLMITTSDNTASLWSQSLAGTG -VAINQLMEKYGFEHTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIREGKMISPAASE -RIYRNLIRIYY-DNDALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCIITKN -QQKHDNEGYALIRNLSKMLWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. SCN 57-10 TaxID=1660094 RepID=A0A1E4LQT6_9CLOT -----KDQISALLAPFGEHGSFVWKDLVTGEGM-EWGAHTPHNAASIIKIPVMVELFRRFE -DGSACKDTLLPLRDCDRVPPCGVLTFHEGMPVSLMDLCWLMITISDNMATNMLINYL-TV -PAIQETMRALGLQNSMLERKLFETDPA-LRNKRNRISAADMALLLEQMHRGELISERASR -EMLDVLSGQQL-NNKIPFLLPLDMHIAHKTGEVDD-VTHDVGIIYAKRPQ---LVCFCSS -D-VDAPAFNQVIFTISKLIFD-- ->[subseq from] ClassA (Fragment) n=3 Tax=Bacteria TaxID=2 RepID=A0A127SGH1_9BACT ------------------------------------------------------------- ------------------------------GDFSLKELLRVTVQESDNNTCDLLFALIGGT -ETVQKDLKEWGISGINVRFTEDEMLRNHELQYANSSRPSAMNALLRAFDEGKILNKDTQR -LLWDMMAGCATGTTRLKGKLPQDYVVAHKTGSGFTTAVNDVGIIVLPNGRKMAVSVFVMD -SKDSAPACEKVIASMARWLCTEw ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. ASBs410 TaxID=1304866 RepID=UPI000452A28E --------IIKKLERIPGKISFLYEDLKTGEGF-AYHEQEPMMAASVIKLFVMAAAFEKSK -KGTFQMDKLFPVKREDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNILIDIL-GI -EEINDTIQGLGFRHTLLQRKMYDIERS-NRGIQNYITAYETGRLLKMMYEGTLIDRRSSE -AMISILKNQQL-CSKIPFYLQESPDIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEVSLELYK-- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. E2A TaxID=2665642 RepID=A0A5Q3Q5U8_9PSEU -----------LPGDCPGRLGFAAWHLDENEPV-LIGQTRQVDAASTIKVLVMITALRAVQ -DGTMRWDSCLPLPEGDRVGGTGVLRELHGLRMELTDLITLMIVISDNVATNTVIDAV-GC -DAVTDTAVSLGCPDTQLQRHLNDMRAQ-AAGLDNVTTAVDQARILAALASGHALDPGTTR -HALGVLARQQV-RDRLPARLPWDARCWNKTGEESC-LRHDVGLIGTGDRPEAVVAVLIDD -LTDS------------------- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces luteus TaxID=1915400 RepID=A0A086N0N2_9ACTN -----TGRLHSAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKVCVLVTLHELAA -AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRTVYGFAEMLGALDPARTNRSTPRDMTRLLSALWRDEACPSEYGA -AMRRVMSLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus insicii TaxID=1732567 RepID=UPI000F7A553F --------------GINGETSAYYFGINDNKKA-SYNYDAEQRAASDIKLFIMAAAYREVS -QGNISLSDRYTLTDADKVSGTGVVQSMQSGDLTYEDLINYMITKSDNTAANIITKQIGGI -SVVNEEINRLNLNDTRMERMLMDQD-ALDSGKDNMSSAYDLALFLKKLYEHKVVSTKYDN -EMLSILSNDSN-HSKLPNQVNTDVIIYNKTGEFGYGVENDAAIFKHDNKA-FVLVVMSQD -GSSS--EQKSAMSSLGKDV---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. RTd22 TaxID=1841249 RepID=UPI00099FE305 ----ARRTIRGLFADAGVRGWLHVADLRRPEACvAIDPDEPVPVGSVYKVPLMVAFWRLVD -AGTLDPCERMTLGPSDRIPPTGISILRDDITVSLRDLVALMMSVSDNTAADVLLRRV-GT -PAVDEVCRDLGMPDTRIHGGVATTFAVYGPVLKSSATPADMARLLRAIWTGRAASADACA -FMREAMGRQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] serine hydrolase n=1 Tax=Emergencia timonensis TaxID=1776384 RepID=UPI00083455B7 ------------LKNCTGKVGFYYKNLITKEKL-AYQENESFIAASIIKLPIFAQVIKVSS -EHRLDLGKEVQIRKEDILPSCGAINLFSSEPLDLRTICNFMIALSDNTATNIMIREC-GI -AALNAGFQEMGLMKTRLERPLFDET-ASMAGKDNYFTPAEIAMLLESLYEERFVSSAVSK -DILQTLKMQNI-NYKIPGLMAERFEVAHKTGEDD-GITHDAGIVYCD--QPFIIVFASNG -TD--------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNH189 TaxID=1136432 RepID=UPI0004651B46 -----VARIHAALADAGVTGWLHALDIDSGEQL-DAGADQPVCTASVHKLCLLVALHERAA -RGELDLTEQVETVPGERTAPTGVAAMLDAARMSLRDLAYLMMAVSDNAAADLLLRRV-GL -DTVNATTARLGLTRTLAVHSFGEMLAALDPARANRSTPRDMTRLLGAVWRDEAGLPEHGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus niacini TaxID=86668 RepID=UPI0005EE5964 ----LKEKIREELNEFEGRIGLAIEI-EDAGNF-YIDNEKVFRSASLIKIPILLAGLGRHK -IGELDLEQLIHISKENRAGGSGILYALSDQLLTVKDLMTLMIIVSDNTATNILIDLL-GM -DEINAFIKEIGFEHTKLNRKMMDFA-AIEKGMDNFTNPREMIHFLKLLNENDIIGITGPP -IAYHALRHQQF-RDKLPAMVNEKITVVNKTGELPS-VEHDCAIFEYQGRK-GYVAVLTDS -FI-DQNAVKQIIRNIGKHISDFf ->[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=1 Tax=Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / VKM B-512) TaxID=1348623 RepID=A0A0B6ADU9_BACMB -------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGSLLRKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-887 TaxID=2682777 RepID=UPI001407E194 ---NLAATVSGIISSYGANASVTLSDLDDYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN -SGYLALEDSYTVQESDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM -DAVNEEVAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ -LATDFLSQQTD-AGGIAPSLSSGETFAHKTGTLTN-VRHDAGIVQ--GEAPYVLSVFVEG -TDEG--SALSLMGEVT------- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus tucceti DSM 20183 TaxID=1423811 RepID=A0A0R1J947_9LACO -----------NLSGIKGDTTAYYYNLDDDTTA-SYDAKTPQRAASDIKLYIMAAAFQKIA -DGDISLNDRYELTNDDKVGGTGVTQNMQAGELTYRDLIDYMITKSDNTAANIITKEVGGM -SAVNDEIEKLGLDNTKMERMLMDQD-ALAEGKDNKTTSYDLAIFMKKLYRHDVVSAKYDK -EMMSVLSNTSN-HSKIPAEINTNVDVYNKTGEYDYGVENDAAILKRDNKA-FVLVVMSQN -GDSD--EQKDAMGSLGK------ ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. RB68 TaxID=2585200 RepID=UPI001294C997 --------IEEVFRAAGVTGHLHAADIDTGREL-GVGSDEPVVLASVFKVALLVAFFREAA -AGGLDPAEQVVLRAADRAPGPTGTAILLDDVMSLRDLAALMITVSDNAAADVLYQRV-GR -GTVNATLRLLGLTRTHLAGGIRDMQDALDPARTTRGTPRETAALLAMIWRDEAAPPAECA -QMRRMLGLQVW-PHRLSSGFPDDIVVSGKTGTMAT-IRNEAGVVEYPDGGRYAVAVFTRS -LLAVLPQADAAIGTAARLAIE-- ->[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. MB-3u-38 TaxID=2058318 RepID=A0A2I0FJ93_9BACL --rKLEAQVENALERFLGQASVVIET--GDDRI-DFNGHAQMKSASTIKLAVLLEAYRQVD -QNLMKTYDLISLKPEDFTEGSGVLFYLDSVKLSFEDLLTLMIIVSDNTASNIAIQIV-GI -DNINQLLQRLGCAETVLERKFMDFHSALEG-LDNYTSAADLVILLKAVDSGGLLSEDSRR -RVLHILKKQQL-LAGLHGRIEDEVTVASKSGSLP-GVVNDAGIFEYRSNK-VYTAVLTAD -SP-DHHSGQELIAEIGGYIYD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus jeotgali TaxID=129985 RepID=UPI0009A566FC --nELKDQLAKELASCKGRASLFLEI--EGRII-EFTGNEVYQSASLIKLPVLFEALRQID -KGILELDRPVAVRQGDRIGSTGVLQAMNIKQITIHDLLALMIIVSDNSAANMVIDLI-GM -DTINSNLSKIGMHNTVFKRKMLDFK-AIQTGDDNLTTCADIVLCLKEAMEGQWLAKQSSQ -LFHAFLLQQQI-QEKLPAQMNSLYKIGNKTGELA-GIEHDCAVITYGTKR-AYAAILIDQ -LD-DNESGKSIIRQIGKRI---- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus apachensis TaxID=309886 RepID=UPI0003A29D99 -------------HGYAGEVGVLITDLAGRELY-ALNPERIFPAASTIKVPLLVRALHEAQ -SGRLDLRERVTVREEDRAGGSGILHEFGPGLPTWEDLLTLMIVVSDNTATNLVIDRL-GV -ECVNGWLDGLGLGSTRLVGKLERQNEAQRRGERNRTAAWDQVNVLGKLARGDLLDPVHTA -LALSILSRQQL-RDILGRHVPRGYRVASKSGELL-GVHHDVGVLFTP--RPLVVALLSEG -GL--------------------- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Atopobacter phocae TaxID=136492 RepID=UPI00046FA53F ------------------------------ASI-SANGNVPIRAASVIKIFILIAFYQQVD -EGAINLEDTYQLRTADKVGGTGNIQNPPGTTYTYNQLATEMITNSDNTTANIVIDRIGGL -NAVNQVIAKLGYTQTKLNRKFLDTY-ALSAGIDNYVTSEELGDVLTKLYQRKLINEKVDQ -SVLDILGKQID-REKLLKNLPTNLVIYNKTGQFDYGVMNDAAIIVTDKG-SYVLVALSMD -GRY--GEKAPAIARFSQNVYQQf ->[subseq from] serine hydrolase n=1 Tax=Rhodothermaceae bacterium TaxID=2026787 RepID=UPI000DD35757 ---ALQARLEHLVEGFRGDVGIYVRHLPTGREA-AIQPDTLFPTASLIKVPILLKTFDAIE -QGVLDYHQPLVYRDSLYYPGEDLIGALKDSSIALSKVVMLMITTSDNTGSLWLQGLVGGG -TAINDWLAAHGFEHTRVNSRTPGREAAREVYGWGQTTPREMAEMLVMIREGRAVSPAASE -EMYRVLTRIYW-NDEALSQLPPTVQTASKQGAVSR-SRSEVVLVNAPHGD-YVFAVITKN -QETHDNEGYVLLRDVSRLLWQYf ->[subseq from] serine hydrolase n=1 Tax=Pedobacter sp. P-25 TaxID=2563444 RepID=UPI00110C89A1 ---KLNKMVNELVKGFNGDVGIYVKSLKTGKIA-AFNADTIFPTASMIKVPITCGIFDKIE -KGELDYKAQLTYKDSLLYAGEDILGSFKNGEIWLAKVLMLMITTSDNTASLWCQSLAGTG -VAINNLMEQYGLQHTRVNSRTPNRQANQRKYGWGQTTPREMATLLTLIRDGKMISPAASE -RIYRNLIRIYF-DKEALSEIPPYVQVASKSGAVNE-SRSEVVLVNAPHGD-YVFCITTKN -QKDTDNEGEVLVRKLSKMLWNYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. RP1137 TaxID=1380110 RepID=UPI0003FFBAA5 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. CNU-125 TaxID=1904961 RepID=UPI0011789F03 ------------FRNAGVTGCCHAVDIDAGRDV-GVRADEPVVLASVFKVPLLVAFHRRVA -AGTLDPTERATLPAADRTSPTGVSALLDDVRMSLRDLATLMITVSDNAAADFLLDRV-GL -AAVNAAAADLGLPATFVAGSGREMLDVRPLDPTSRSTPREMTRLLSLVWRDEAAGPGECA -AMRRMFGLQVW-PHRLSSGFPEDVVVSGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT -PVAVHPQGDAVIGTAARIAVEH- ->[subseq from] serine hydrolase n=1 Tax=Planomicrobium sp. Y50 TaxID=2213011 RepID=UPI001091DCF7 -----EFQVKKALEHSSGKVSLAIET--KNGRI-DINSHKQMKSASTIKLAVLLEAFSQID -RDLVKPYDIIRLQPEDFTQGSGVLIHLGSVKLSFEDLLTLMIIVSDNTASNLVIRTV-GI -DSVNALLNRLGCNETVLGRQFMDIQAALD-GLDNFTSAADLVTMLKVVDSGELLSEDSRR -RVLHILKKQQL-LANLHGRIDDEVSVASKSGSLP-GVVNDAGIFEYRGDK-VYAAVLVSD -SP-DNHSGQEVIAEIGGYIYD-- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus sp. 184-8 TaxID=2486005 RepID=UPI000F7A7A4E ------------LSNIKGDTSAYYYDLNNNSTA-SYDANSAQRAASDIKVYIMAAAFQKIK -DGDISLNDRYELTSDDKVGGTGIVQDQVGDSLTYRDLIDYMITKSDNTAANIITREIGGI -SSVNSEIDKLDLSSTKMERMLMDQ-DALDEGKDNMTSAHDLAVFMKKLYRHDVVSAKYDK -KMLEILSNTSN-HSKIPAKINTNVDVYNKTGEYDYGVENDAAILKHGNKA-FVLVVMSQN -GDS--DEQKDAISSLGKDVTQ-- ->[subseq from] Beta-lactamase n=1 Tax=Citrobacter koseri TaxID=545 RepID=A0A2X2YN99_CITKO ------------------------------------------------------------- ------------------------------------------------------------- -------MRDSGDTITRLDRYEPELNSAIPGDERDSTTPVAIAQTLNTLLLGNVLQLSSRE -QLMQWMRDDKVADGLLRSVLPDGWKIADKTGAGDNGSRSIVSVVWPTSQKPLLVVIYITQ -TPATMAQRDAAIVRIGESLF--- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. J1-007 TaxID=2661913 RepID=UPI00132122C8 ----VTARIEAAFRAAGVTGHLHAADIDTGREI-GVRPDEPVVLASVFKVPLLVAFHRQAA -AGLLDPTEAVTVRPEDRSAPTGISALLDEVRMSLRDLACLMITVSDNAAADVLLDRV-GL -AAVNETAARLGLPRTYVDGGGRDLYDGLDPARTSRSTPREMTRLLGLVWRDEAAPPDGCA -AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLLT-VRNEVGVVEYPDGGRYAVAVFTRS -SLAALPRADAVIGTSARMAVE-- ->[subseq from] serine hydrolase n=1 Tax=Mycolicibacterium madagascariense TaxID=212765 RepID=UPI00138D7E7F -------RIAAVFADAGATLHAVAVDGSSTGEV-NVDGDRPVALASVYKLPLLVAMMRMVD -GGRLDLTERVTLRPTDRTAPSGISALLDDVTMSWRDLAAMMMSVSDNAAADAILQRV-GV -DEVADALSALGLTRSRILGGTADAYRAYDPLQSSSATAREMTTLLRTIWTDVAASPASCA -TIRRLMSLQVR-SNRIASGFAAGVSVAGKTGTMG-ALRHDVGVVRFDGERPYAVAVFTQS -ARATQPRIDAAIGQAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Fischerella sp. PCC 9605 TaxID=1173024 RepID=UPI0012DCD1B9 -------NFTSLISGFRGTAGIVIRNLDSGHDA-QFNQELLFPAASLIKLAILWEFFYQCA -IGVVDPVEEIELQAQDMVIGFGVLRQNPGLKLRLLDLATLMIVISDNTATNLLIDRL-GM -DNINNSIQQLGLVNTALQYKMFDPRDV---NRDNFTSPADVARILEAFVRQRQLLGQYGD -EPLRILEGQQC-KNKLHLGLPKGVQLANKTGELLW-IEHDAGILFAKDKE-IVIVVMTQG -LSEN-YDGIRLCRDVAKLVYQ-- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A534HVR7_9GAMM -----------------------------------------------MKVAVLIELYRQAR -QGKLKLDDPLSVKNESLVDGSAFAYRAVGGTRTLRELSELMITVSSNLAANLLMDRL-GV -ENIRAGVHALGADGMNVLRDLEDAKA-FEQGLVNTTTAQALLTLLEAIARGQAVDRESSR -QMLETLERQTI-NDGIPAGLPAGTRVAHKTGDITR-IWHDAGIVLA--RRPFVLVVLTRG -LEN-PKESTALIAEITRELYR-- ->[subseq from] Beta-lactamase n=2 Tax=Pediococcus claussenii TaxID=187452 RepID=G8PER7_PEDCP ----------------SGKNSFYIGPTDTKISP-YSQNNAPQRAASDIKIYVMATVFSQMK -QNKFDMNDTYTLKDSDKVGGTGKVQNMGDGTLSMQELMDYMMQDSDNTAANIIIRKLGGL -NVVNDEITHLGFKDTKLERYLMDTD-ALKEGKDNMTSVNDLGTILTDIYNKKLISSSYDE -QMLQILNQDED-HSKLLEEIPGSVSTYNKTGDYDYGVQNDAAILSENGR-SYVVVAMLEN -GSKD--DQTSALNDLGKQVYEKy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. KPB2 TaxID=2305221 RepID=A0A3Q8VX05_9ACTN ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GTGADQAVCTASVHKACVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Sphaerisporangium album TaxID=509200 RepID=A0A367FQB4_9ACTN ---------AGVFRAAAVTGTVHAVDLDTGAEV-GVGPDEPVVLASVFKLPLLVEFHRQAE -AGLLDPAEPCRIGPEGRTAGTGLAAMLDAATLSLRDLAYLMIAVSDNAAADVVAARV-GL -KAVNAMLTAFGLTNTWIEHDCRGLLAVLDPANTNRSTPREMTRLLGMVWRDEAAGPPACA -AIRRLLGLQVW-PHRLASGFPDDVVVSGKTGSLPT-IRNEVGVVEYPDGGRYAVAVFTRS -LGQNQPRADAAIGTVARAAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID10362 TaxID=2706021 RepID=A0A6B2RNR8_9ACTN ----AAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKACVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGAAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces diastaticus TaxID=1956 RepID=UPI000C9A2610 ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKACVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1FKA2_9BACT -----LTQIKKIIDQQPGNYSVYVLDLINNQAF-GINESVILTAASVNKIPILATLYKDAA -AGTIDLNEIITLQPNDIQYGTGILQGEGPGGYSLKSLAQLMIKKSDNTAAFVLMQKL-GA -TKVQGTVNNLGLTQTNIEE--------------NLTSNKDMALLFQKIYSGQIVTKTNTR -ALLEMMSNSDF-ENRLPALLPKNVKVYHKIGTEV-GFVHDVGIVETIGH-PYYIGVMTSD -ISG-EEQAETTIGQISLLVYQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Veillonella atypica TaxID=39777 RepID=A0A133S5Z3_9FIRM -------------------------------------QSHRVRAASMIKVYILSYLFEKID -KGEISLQDVYVLKPSDKVGGSGVLNGYESGSLSIDTIARLMITESDNTATNILIDKL-GL -ENINLYISTQGYKDTQLNRKMMDVN-AIDKGIDNYTSAQDLGNWFLKLAAGKMASDLSNK -QMIDYLVGQTD-TECISAALPN-RIIAHKTGELA-GVYHDGGIIYNANHNDYYILVLLSD -GYDSRTGTIESFRSIARQV---- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacteriaceae bacterium DW12 TaxID=1550091 RepID=UPI0005323211 --dKLTKKLTEAIAEFKGEVGIYVKKMNSNKEV-AIHADEIFPTASIVKVPILVGLFDKIN -NGELKYKQKFIYRKDRIYGGSGLMQFFKDSVTDLATMAALMIGYSDNVTSIWCQELA-EG -TKINNIMDKLGLKNTKVNSRTPGREAAWKEYGWGNTTPREMANLLIMIRKGQVINPSISD -KMYRVLGNVFY-NERSLSQVPAHIKTASKSGSLDD-VRSEVVLVNAPSGD-YVFSIFTKN -NQGQTNEAEDLTRRISNLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Planomicrobium okeanokoites TaxID=244 RepID=UPI0009FEC424 --rKLEAQVKNALERFLGQASVVIET--GDDRI-DFNGHAQMKSASTIKLAILLEAYRQVD -QNLMKTYDLISLKPEDFTEGSGVLFYLDSVKLSFEDLLTLMIIVSDNTASNIAIQIV-GI -DNINQLLQRLGCAETVLERKFMDVHSALEG-LDNYTSSADLVTLLKAVDSGGLLSEDSRR -RVLHILKKQQL-LAGLHGRIEDEVSIASKSGSLP-GVVNDAGIFEYRSNK-VYTAVLTAD -SP-DHHSGQELIAEIGGYIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_20CM_2_65_9 TaxID=1803428 RepID=A0A1Q8ASG7_9BACT -----ASRAGEIAAGLDGALGVSVFDYLSGFAW-GLDGDRWFHAASTIKVAILAGLFDAIE -RGRFTLDSRLHVRNRFLSGGQPFRHASIGKTMRVGELARHMIVRSSNLAANLLLDLV-GV -EETRAALAARDITGVDVCRGVED-ERAFEAGLSNRVTADGIVGLLRAIRDGRGFSPESSK -AMIDILMDQEF-AGGIAPGLPAVARVAHKTGDIST-VSHDAGLVFLPGRPPYVVAILVAC -AS-DASARTEALAAISGLVYD-- ->[subseq from] serine hydrolase n=1 Tax=Planococcus sp. CAU13 TaxID=1541197 RepID=UPI00052FEDF3 -----KSRILTTLGEFTGRVSAVIE--TAGKRI-DINGNARLKSASTIKLAVLLEAFRQVD -REILKPHELIPLHPEDFTEGSGVLFRMNSVKLSLEDLLTLMIIVSDNTASNVSIRTV-GI -ENVNRMLEELRCSETVLGREFMDFRAA-AEGADNWTSAADLVKMLKAVDLEGFVSPDSRK -RVLHILKNQQL-IANLHGRIDAEVEVYSKSGGLP-GTVNDAGIFEYRGHK-VYAAVLLDD -SP-DNHTGQEIIAEIGGHIY--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces purpureus TaxID=1951 RepID=UPI00036EDCA9 -----RTLLASAFTQAGVEGYVHARDLETGAEF-GHGADTHVVLASVFKIPIALEYARQAA -AGELDPARRHTVTAAYRAGGSGTDGCAYDVEMSARDLAFMMMTISDNAATDLLLDVV-GP -DRVRATLDDLGFKDFGFSSSAA-LDDACAPSTSPSSTPREVTALLAAIWRDEAGPASACA -EVRDIMGQQVW-QHRLVSGFPAGVRIAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT -STAAQPLADRAIGRAARIAVDH- ->[subseq from] Serine hydrolase n=3 Tax=unclassified Synechococcales (miscellaneous) TaxID=1983103 RepID=A0A3D0PDN6_9CYAN --qALSRRLAEIAAQKDLKVGAFVLVLDDGTFA-QLHPDRPLSAASSIKTPILLVAFEALD -QAKLSLNEALSLNKTVVGGGAGWMGSQPGSQFSIFEVATEMIRVSDNTATNLLIQRLGGK -DSLNARFIELGLEGTMINNWLPDLEGT------NTTTPRDQARAIALVETGQTLSPRSRD -LFRQTLGTSRT-DTLIPRGWLRGVRVYNKTGDIGI-AYVDSALVELPDGRRVVASYMVEG -PFND-PRSTNMIRALAAA----- ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus phoenicis TaxID=1476583 RepID=A0A016QLP6_9DEIO -------------RGYAGEVGLVITDLTGQELY-ALNPARVFPAASTIKVPLLVLALWEAQ -AGRLDLRERVTVRAEDRVPGAGVLHELGAGLPTWEDLLTLMIIVSDNTATNLVIARL-GT -ERVNGWLRERGLLGTQLVGPLERQNEAQRRGERNRTTARDQAALLGALVRGELLDTAHTG -RALSILSRQQL-RDILGREVPCGYRVASKSGELR-GIHHDVGVLFTP--RPLVVALLSEG ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF2CFE1 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Anaerocolumna sp. CBA3638 TaxID=2696063 RepID=UPI001373A736 ------ERLLEQLKSLKGDISFYYKNLITGEVI-GFKENIPLEAASVIKIPILIEAFLRIS -EGNIHKDDIIAIKKEDKLPSCGALNYHDGLRVTFEDLYTLMIILSDNTATNLLIKQL-GM -DNINITMQNLGLKQTKLNRLLFDAKQS-ALGIQNYISAGEMGYLLEKMYFGELISPESSL -EMLRILKNQRL-NGKIPFYIHGRADVAHKTGEDD-GITHDVGIVYAPQ--PFVVCF--CG -NKVDVPVFERFMQDITLT----- ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Pediococcus claussenii TaxID=187452 RepID=UPI0009F443A0 ----------------SGKNSFYIGPTDTKISP-YSQNNAPQRAASDIKIYVMATVFSQMK -QNKFDMNDTYTLKDSDKVGGTGKVQNMGDGTLSMQELMDYMMQDSDNTAANIIIRKLGGL -NVVNDEITHLGFKDTKLERYLMDTD-ALKEGKDNMTSVNDLGTILTDIYNKKLISSSYDE -QMLQILNQDED-HSKLLEEIPGSVSTYNKTGDYDYGVQNDAAILCENGR-SYVVVAMLEN -GSKD--DQTSALNDLGKQVYEKy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB02959 TaxID=2020330 RepID=A0A2M9LVX5_9ACTN ---TTRRRIRAAFAGAGVTGRLHALDIDSGAEV-DAGADDAVVTASVHKLCLLVALHQQAA -AGRVDLTEQIECPPDSRTAGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAAGLLLNRV-GL -EAVNSTTAGLGLPRTRAVHTFHEMLAALDPARTNRSTPREMTRLLGAVWRDEACPAEHGA -AIRRLLGLQVW-PHRLASGFPDDVYVAGKTGTLPT-VRNEVGVVEYPDGGRYAIAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI00094FD6CF ---TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT -RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV -PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA -AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNGISRQVYGHf ->[subseq from] Beta-lactamase n=2 Tax=Komagataeibacter hansenii TaxID=436 RepID=D5QC17_KOMHA ---TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT -RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV -PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA -AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNGISRQVYGHf ->[subseq from] serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI00094FCC51 ---TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT -RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV -PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA -AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNGISRQVYGHf ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus tucceti TaxID=238012 RepID=UPI000708ED30 -----------NLSGIKGDTTAYYYNLDDDTTA-SYDAKTPQRAASDIKLYIMAAAFQKIA -DGDISLNDRYELTNDDKVGGTGVTQNMQAGELTYRDLIDYMITKSDNTAANIITKEVGGM -SAVNDEIEKLGLDNTKMERMLMDQD-ALAEGKDNKTTSYDLAIFMKKLYRHDVVSAKYDK -EMMSVLSNTSN-HSKIPAEINTNVDVYNKTGEYDYGVENDAAILKRDNKA-FVLVVMSQN -GDSD--EQKDAMGSLGK------ ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus radiopugnans ATCC 19172 TaxID=585398 RepID=A0A5C4Y515_9DEIO -------------QGYGGEVGLRICDLVGQELF-ALNAARVFPAASTIKVPLLVLALEWAQ -TGRLRLEDRVTLQAADRVPGAGVLHELGPGLLSWRDVLTLMIVVSDNTATNLLIDLL-GV -ETVNTWLEARGWSQTRLVGGLERRNAAQRRGERNCTSALEQTDLLGRLVRGELLDEVHTA -LALDILERQQL-RDVIGPGLPRAYRLASKSGELD-GVHHDVGILYTP--RPLVVALLSEG -GAD-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Aquiflexum balticum DSM 16537 TaxID=758820 RepID=A0A1W2HBA1_9BACT --qSLQRFLESEVKDFKGDVGIYVYNLKTNEEV-AINADTIFPTASIVKVPILVGVMDKIE -KGELEYHQKLVYRDSIKYGGSGLMQFFQDSVTELSVLMSLMITYSDNTTSLWCQALAGGG -ERINEIMEGLGLEHTRVNSRTPGREEIWKVYGWGQTTPREMAQLLVKIRRGEVISRKASE -RIYRLMSNIFY-DEYSLSAIPPYVQTASKQGMVN-ASRSELVMVNAPKGD-YVFYIATKN -NEEEDNAAYELQRKVSRILWEWf ->[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum odellii TaxID=2290917 RepID=A0A398DDC3_9BACT ---NWQEQVRALFGSAQGKFGVYAA-TATTPLF-EYQASSIFPSASTIKVLIMAELLRQVE -AGTHSLSEHPALPT-APTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIHLT-GM -DAVNQLAVDIGMTNTRLRRFMMDTESM-QQGIDNTTSPADMGRFFKLLACNELVSSRASA -TMKTILGRQQF-SHIMMLFLPEGIQVEHKTGGLP-GSVLDVGLVYSA-RDPLILCLMATQ -LAN-NGEGAVILGKVAEIIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium Isolate-007 (NCI) TaxID=2489217 RepID=A0A4Q0INX5_9BACT ---HIEERLATYIAAQDARIGVAVI-IDGRDTI-SVNGNRDFPMLSVYKFPQAMAVADYCM -KNGVGLSDTISIRGDEMKEWSPMRDRYGVGDLPLSELLEYSLRDSDNNACDILFRLIGGT -HVADSLMKAMDFDDIVIASTEDEMHRDIYLCYQNRSTPIAMAGLFDRFYRQEMRHSPLHE -AIGRIMMTCTTGNRRLPAPLPTNAVIGHKTGTGDVNSQ---------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H0MSE3_SELRU ---ALAEAITGLSNADSTRYSLYAAYPQESREP-YIYQSEPMRSASMIKVFLLADAMEKVR -DGQLALNTGITLHSKDKVGGAGVLCGYASGTLPLDTVLRLMITESDNTATNLIIDLL-GM -DDINAYIRRNGYNDTTLARKMMDFAA-VNAGRDNYTSVTDLGNIFQRIYNHECVGYEQDE -IMLSYLKGQTD-TECFPAALP-GAVIAHKTGELG-GLYDDGGIIYQNGRA-IILVIMTEH -YSN-RYRAIETMKAMAQSVM--- ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus geothermalis (strain DSM 11300) TaxID=319795 RepID=Q1J1L5_DEIGD --------------GYVGEVGVLITDLAGRELY-ALNPDRVFPAASTIKVPLLLLALSEAQ -AGRLDLSGRVTLRAEDRVPGAGVLHELMPGLPTWQDLLTLMIVVSDNTATNLVIERL-GL -DRVNDWLGERGLSGTQLVGPLERQNAAQRRGERNRTTARDQVALLGALVRGELLDRSHTG -LALSILERQQL-REILGRHVPCDYRVASKSGELM-GIHHDVGVLFTP--RPLIAAVLSQG -GL--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174QS40_9CLOT ----IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEAFETASTIKTYILACLFDQVE -KGKASLEDMVEFKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA -KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK -FSDAAHPATVFGARVSRLLFDQf ->[subseq from] Uncharacterized protein n=3 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358IF26_9BACT --dSLQSRIAARLDRLDAMSSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA -SGRLDFGERYTIGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -NRVNALLQSEGFSQTRLKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA -EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ -NTGDFFDLEATLGLIAEDIVEAw ->[subseq from] zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus modestisalitolerans TaxID=1457219 RepID=UPI0010FA3E5F ---AVRQRVQSQVVNLAGTTSVAVRATSGRGQV--VHNNRQQRAAGLAELFVLAAVYQQAQ -TGKLTLTQRVTLQAQDRVAGTGQLQTMPAGSFTVANLAKRMIVDSDNTATNLLIDQLGGV -TATQRVIQQLGFTKTELNRKMMDTS-ALKAGRDNQTTVNDVAALLRQLYRGTLVAKTADQ -TMLKLLKQTQ-GPSNLGANLPSSATVYHLAGTYSYGVQNEAAIVQNRHGA-FVVVMLAEN -GQAQ--AQTKRMRQ--------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00101B745B -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLKALPRVTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKDLGLKKTLLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNFLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces aureocirculatus TaxID=67275 RepID=UPI000561A1E4 ------TRIQEAFAEAGVTGKLHALDIDSGAEL-GTGADQAVVTASVHKLCVLITLHEQAA -AGLVDLTEQVECPPDGRASGPTGLSAMLDPVMSLRDAAYLMMAVSDNTAAELCLSRV-GL -DAVNATTARLGLTRTRALHTFRAMFEALDPARSNHSTARDMTRLLRALWRDEACTPEHGA -AMRRVLGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ARATLPSADAVIGTAARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BA60B85 -------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSAIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGSLLRKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 66b TaxID=1945511 RepID=UPI0009BA88E2 ---SAQQEIAAVLAEAKTDAFVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLSLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HEHRAPKIDASIGTVGRIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nubsella zeaxanthinifaciens TaxID=392412 RepID=UPI000DE335F3 ---KLNKMINELAKGFNGDVGIYVKSLKTGKIA-TLNADSIFPTASMIKVPITCGIFDKIE -KGELNYNTQLVYKDSLLYAGEDILGSFKSGEIWLAKVLMLMITTSDNTASLWCQSLAGTG -VAINQLMEKYGLQYTRVNSRTPDRQANQRKYGWGQTTPREMATLLTLIREGKMISPSASE -RIYRNLIRIYF-DKEALSEIPPYVQVASKSGAVN-ASRSEVVLVNAPHGD-YVFCVITNN -QKRYENEGEVLIRSLSKMLWNYf ->[subseq from] serine hydrolase n=1 Tax=Cyanobium sp. Copco_Reservoir_LC18 TaxID=1328305 RepID=UPI00135B8038 -----SQQWARLAAQKGLTASGFLLVLDDGRYA-ELQPDLPLSAASSIKVPILLAGLEDLD -RGKVRWNEPMPLTKEVVGGGAGWMAKPLGTRFPFFEAATEMIRVSDNTATNLLIRRLGGK -TELNGRFRSLGLTATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGDKLTPRARD -LFREIMGTSRT-NTLIPELLPEGITVYNKTGDIGI-AYSDTALIQLPNGQRAVLAVMVKG -PFND-PRSAELIRSMAGAVTK-- ->[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=A0A318Q142_KOMHA ---TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT -RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV -PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIVGPAQSA -AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTRS -LP-DEAAGIRVLNGISRQVYGHf ->[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6MMJ1_9BACT --dSLQSRIAARLDRLDAMSSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA -SGRLDFGERYTIGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -NRVNALLQSEGFSQTRLKATTGDLFRAFQGDSTGKTTAREMGNLLEQILNAELADEEASA -EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ -NTGDFFDLEATLGLIAEDIVEAw ->[subseq from] serine hydrolase n=1 Tax=Streptomyces coelicoflavus TaxID=285562 RepID=UPI0013DC9ED7 ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKVCVLVTLHELAA -AGGLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAYLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPAEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura fibrosa TaxID=111802 RepID=UPI00104138D6 ------------FRDAGVTGCLHAVDVDTGREV-ALGADEPVVLASVFKVPLLVAFHRQAA -EGVLDPAEQVTLRPEDRTPPTGVSALLDEVRMSLRDLACLMITVSDNASADALLERV-GL -DAVNATAAEFGLTGTLVLDSGREMLDALDPARTGRSTPRDMTRLLGLVWRDEAAPPAECA -AMRRILGLQVW-PHRLASGFPDDVVVSGKTGTVPT-IRNEIGVVEYPDGGRYAVAVFTRS -ALAVLPQADAVIGTAARLAVE-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 (Fragment) n=3 Tax=Acinetobacter baumannii TaxID=470 RepID=B5B4Y5_ACIBA -----------------------------------------------------MLVLHQVD -QGKLDLNHTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDYVACDLLFELVGGP -SALHDYILSMGIKETAVVANEAHMHAHHHVQYQNWTSMKGAAQILKKFEQKTQLSETSHA -LLWKWMVETTTGPERLKGLLPAGTVVAHNTGTSGTAATNDLGIILLPDGRP--------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000D51CA77 -----AGRLHAAFADAGVTGLLHAVDIDSGAQV-GAGADQPVCTASVHKVCVLVTLHELAA -AGEIDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLAALDPARTNRSTPRDMTRLLTAVWRDEACPPQYGA -AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=A0A561U6W1_9PSEU ----AEQRMRDVLADAGAQGWVHAVRLGGGHQL-GIGADELVVTASVYKLPLLVALARAFD -SGVLDPREPIRLEPTSCTPPTGVSIFQDPVRMSWRDLAASMIAVSDNAAADVILGAV-GL -EAVTAALADLGLERTRVVGGTAESHAAYDPSYASATTPHEMTRLMELIWSDEAASPHQCE -FVRGLLGQQAW-MHRVRAGFPQGVRVAGKTGTIG-AVRNEVSVVEFDGEAPVAVAVFTLA -ARADLPRVDAAIAECARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium lactis TaxID=797291 RepID=A0A1H5UIF9_9SPHI --kALEKKIHAAIAEFQGEFAFYSKHLKQHKEV-AINADELYPTASVVKIPILVGVFQKIA -NGELRLDQQLTYRDSRAYGGSGIMQFYKDSTTDLATLIGLMLSYSDNVTSIWCQELAGGG -LAINPIMESLDLKYTKVNSRTAGREEDWKKYGWGQTTAREMSQLLEKIRLGKVISPQYSD -KMYRFLKNQFY-NGRSLSQFPAEINCISKTGSLED-VRTETVLVNAPHGD-FVFTLLTKN -NKDNTNEAEILTRKIANIIWNHy ->[subseq from] Uncharacterized protein n=1 Tax=Leptolyngbya foveolarum TaxID=47253 RepID=A0A2W4W4Q5_9CYAN ---KLQAQLDKLTTLYELQFKAFYIDVDTGDYV-DIDGRGAIAAASTIKLPILLAFFEEID -KGNIDPNQTIAILPEQIAEGSGDMQISPPGTFTAIEVATQMIVNSDNTATNMMIDLLGGA -EVLNERFVSYGLEETRLNNPLPDIEGA------NTTSARDLVHSM-LLVQSDRLKMRSRD -RVLNILERTEN-KRLLPAGLEQGALTYNKTGFIDK-MLGDVALVDLSNGKRYVISVLVES -PDND-GRALDLIHGISERTF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK208 TaxID=2512150 RepID=A0A4R7JCJ4_9ACTN ---STAARLNAAFTDAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVALHELAA -AGALDLTERIECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLVRRV-GL -DAVNRTTARLGLTRTRAVHGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium amethystogenes TaxID=2002 RepID=UPI0004C7A2B7 ----TEERIAEIFAAAGLDGHLHALDITGGREV-GVRADEQVVIASIFKVLLVLEFARQAA -AGQLDPAERVLVTAEDRLGGWGTAGCADDMEMSLRDLAHFAMSVSDNTAADLLMRRV-GL -DTVQMLAAELGLVRTRVIGGPRQVLEVFDPGHTTSSTAREMTRLLGLIWRDEAGPPQACA -AVRDYMARQIS-WTRIASGFPPEVRVAAKTGTLP-GLHMEVGVVEYPRGGRYAVAVFART -EQLHATRRDLAIGQAARVAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HSH5_9CHLR ---DLVQQLDQLSASFPGGVGLWIADPNATRPLySHNADEHVITASLYKLGVLMEAERRVD -TGELKYSDPMTITEEDVMLDGSF--EGAGTDLTIDQALEAMITISDNGSARALWRLL-GP -ENIDVTLQKAGITDFHVQLTD---------YEDNVATPRAIGQFFTLLATRKLISPAASD -RMLARLERQEI-NDRLPAALPDNVVVAHKTGNLV-GAVHDAGIIYTPSG-PRVVVAMTWD -AY--DEEANALIANIGAIVYS-- ->[subseq from] Beta-lactamase n=2 Tax=Fibrella TaxID=861914 RepID=I0K5M1_9BACT ---RLTQQLADALRGFRGDVGVYVRHLKTGKTV-AINADSTFPTASTIKIPIMIGLFDQIQ -KGTVSYEQELVYRDSLHYDDGIVGSLRDGAKIPLSQVVMLMETVSDNTGSLWCQALAGGG -TAINAWLDANGFPNTRMNSRTPGRKEFQARYGWGQTTPRELASLLTYIRDGRAVSPDASD -RMYRNLCRQYW-DHDGLSQLPANVKVASKNGAVNR-SRSEVVLVHAPHGD-YVYCLMTKN -QQDETNEGSTLLRTVGALLWQHf ->[subseq from] serine hydrolase n=1 Tax=Komagataeibacter hansenii TaxID=436 RepID=UPI000789B239 ---TLAQDVAKTVSGQPGSFAVYAAMSGQRPQV-CLNCTDYINAASTMKLFVMDAAYDMFT -RGTLQPQETIVVHNRSLVGTRSFSYAQIGRPVTVSELVRVMIQYSSNLATNLMVERI-GV -PYIHAVMHAQHLKGVRFGRMIEDYDAN-DKGIRNEMTAKGLGMFMQKLDQGKIIGPAQSA -AMIDILRGQTF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNGISRQVYGHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces coeruleorubidus TaxID=116188 RepID=A0A5J6I7K1_STRC4 -----LTRIHAAFADAGVTGRLHAVDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGFLDLTEQVECPPEGRTAPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL -DAVNRTTARLGLTGTHAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACTPEHGA -AIRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSQPAADAVIGTAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB09001 TaxID=2083284 RepID=A0A346C2L2_9ACTN -----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADRPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVHGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A326QE10_9CYAN ----LSARWKALAAQKDLKVGGFLLVLDDGRFA-QLNPDTPLPAASSIKTPILLAALEDLD -RGKLRWGEPLPLTKEVVGGGAGWMANRPGTRFPFYEAATEMIRVSDNSATNLLIKRVGGK -LAINARFQALGLPATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGAKLSPRARD -HFRTILGTSRT-NTLLPAGVLKGITVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG -PFND-PRSTDLIRAMAATM---- ->[subseq from] Serine hydrolase n=1 Tax=Halorubrum sp. 48-1-W TaxID=2249761 RepID=A0A329T8M5_9EURY ---DLARAIDSIADRFDGRLGVFLCVPRGADAFhSRNADEEFVAASVIKLPILYALYEAYD -GELDRLGEPRPIAAENRVGGSGILHLFDDPTSTLEDLARAMIAISDNTATNQLIDEL-GA -DRIERTAARLGMDDTRLRRKMMATLGQLEGRPANATTPADCARFFADLVHEATLSAPAYE -RLRVPLDEQKD-RSLFPRYLPYRTPIAHKTGGLPT-AALDAGVLRSADASPLVFSAFATR -AENG-GDAGDAVAAVGEVAFE-- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537I206_9BACT ---KLFKKVSEEINGFNGDIGIYVKNLRTGKTI-AINADTIFPTASIVKVPIMIGVVQKLF -TGEITYDSAFTYKDSLLYAGADILGSFKTDEIALKKLLMLMLTTSDNTASLWLQSIAGTG -TRINELLDSFGLKNTRINSRTPGREEYRSKYQWGQTTPYEIGTVLEKIYKNEIFSKELCD -RMMRMLGRNFWDEDEAISQIPPYIEVFSKNGCVN-AVRSEVTIVNAPHN-PYVFSIFTKN -NKTHENEAWTLARKISRLLWDYf ->[subseq from] Uncharacterized protein n=1 Tax=Leucobacter sp. G161 TaxID=663704 RepID=A0A0W7WBN7_9MICO --qSVSEAIAEAATAAGVSVFAHARDLDSGAEV-GYHFDEPTVTASVFKVPVLLEYVRQVA -AGELDPAQRILVSPASVTRGPTGLSVFSDETWSLRDIATSMITVSDNAATDIVVELV-GV -DRVNATMAELGLPGTQLVGDCATLFAASTPAKTNRSTPREATRLLELLWTDAAATPAACA -EARRILGLQVW-PHRLSSGFPDDVKISGKTGTLGI-VRNEIGVVEFADGRRHAIAVFLRS -TESRNPKADRVIGTVARLLSD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536ATC9_9CHLR ---ELVQHLDQLVGSFPGGAGLWIADPNASKPLySHDADEPIITASLYKLAVLAEAERRVD -AGQLHYSDIITIENEDITEDGSF--EVAGTELTLDQALEAMVTISDNGAALALWHVL-GA -DNINATLRNVGINDFHVFV--------AYGEDDNIATPRAIGTLLTLLAKRQLISAAASD -RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD -AY--EADAYAFIANVGSIVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HE47_9BACT --eRLQNELEAVVHRFDGVAGIHVVDLTDGRRF-DVRGDLIFPQASAIKITILLELFRRAE -TDPGLLRKRVELTEAVRTGGSGVLNILTDGGLSLEDHAIYMIVYSDNTSTNVLLDEL-GM -AEVNALAASLGAPQTIFQRKMIQPEAS-ARGDENLSTPREAARIMERIAACELMSAAACA -RVTEILALPKGGP--ARAAVPASIPIAFKPGGIT-GVATVWAVVQLPGR-PYVLSVMANY -GG----DGGSVVREASEAAYSYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z6X2_9CHLR ---RLAEEVVSVLRGRDELVSIAAVHLLDGTGV-ALNADDVVPPASLFKLNILAETYRQIE -RNRVKLAQMITILPEDAAPGAGILQDRIGEAVSVGEALSLMIGISDNTAAFALLRTI-SS -RKLNECTRALGMLRTWFYVDER----------PDETSAGDVVTILRAIIDGTIASPRGTD -QMLELMTQVQP-SAWIRSGLPPGTRLAHKSGQLE-GIRNDAGIVFGPTG-PYALAVLTHD -LY-DPAVGEQIITAVTRVVHRYf ->[subseq from] Putative Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces afghaniensis 772 TaxID=1283301 RepID=S4MRG0_9ACTN -----LDRIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGLLDLTEQVECPPESRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL -DAVNRTTARLGLTRTYAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACIPEHGA -AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSQPAADAVIGTAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. MED-G68 TaxID=2267259 RepID=A0A4V8DEL2_9SYNE ---ALSKRWEALAAQDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVALEEID -AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRISDNTATNLLIERVGGQ -EDLNARFTSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD -LFREVMGTSVT-NRLLPGGLLKGYRVFNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG -PFN-DPRSTELIRNMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A1Q8URJ5_BACME -------------------NGLIRIHIEGKESI-QINSFIPQRAASTIKLLLAIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSVFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sordidisoli TaxID=2502893 RepID=A0A4Q2UTJ2_9BACT --sTLEKRLQTALTGFRGDVGVYVRNLRTGQTV-AINADTLFPTASTIKIPIQCGLFDKIH -QGELTYGQVLTYKDSLRYGDDIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG -AAINAWLDKNGFPQTRVNSRTPGRKGYWSQYGWGQTTPRELANLLVYIREGKAVSPDASD -EMYRNLGRQYW-DNDGLSQLPPEIKTAAKNGAVDR-SRSEVVLVHAPHGN-YVYCVMTKN -QKERSNEGFTLLRNVSAILWQHf ->[subseq from] Uncharacterized protein n=1 Tax=Pontibacillus yanchengensis Y32 TaxID=1385514 RepID=A0A0A2TAX5_9BACI ---SLEKKVTNIVSTLNAKASVVIRT--NYGTI-AINEKEIMPAASVIKIPIMMEAFRQAR -TEGGDLSAPVTIPQHNKVGGAGVLQFLSQDTFSLYDLVKLMIIVSDNTASNAVIRSV-GM -EAINRMIEELGCWNTKLRREFMNLKAQ-GQGFDNTTTAEDMVNLLEQLALHD-------R -EMVEILKGQQLTSQLPAYNTYEDLEIANKTGELD-GVQHDVGMFVDSYQ-SVYVAVLLNE -VG-EAVEAQRAIADIGHQVMQY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7EA23_9BACT ---ALRKTLDSIADAHHGIVGYSVIDLETGARI-SRHGDETFPTASLIKVAILATVYDLVA -KGQLSLDDPLTVLKIDQVPGSGIVQFHNGTVLTIHDAAWLMSTISDNTATNLLLDRI-II -RRVWAKMDSLGLQHTRVHSKSFLRNSSVAMDSSGVTTPNEMAHLFELMAQGKTVNPSADS -TMLDILEHNGT-DFMLQRYA-GGARAAHKDGETD-AVRTECTLWYLRNR--VVACVMTKE -NKDQDNEPQLTMANMGLAIIN-- ->[subseq from] Serine hydrolase n=2 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A413X4V9_9CLOT ----IEKRIEAELMSYDGIMGIYADDLH-GNII-AIGADEPFETASTIKTYILACLFDQVE -KGKASLEDMVEYKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA -KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK -FSDAAHPATVFGARVSRLLFDQf ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF92C1B -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRTEKNTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMLDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=candidate division KSB1 bacterium TaxID=2172550 RepID=A0A3A0DY23_9BACT ----LTKKVLQAIDGFKGEVGVYVRHLKSGKTV-MIRADELFPTASMIKVPILLTAFQKIQ -EGELDYHGEQTYRDSLLYAGEDILGSFKDGEIKLSKVIMLMITTSDNTASLWCQKLVGTG -TAINEWLQAHGFSQTRVNSRTPGREADREKFGWGQTTPREMAELLVMIREGRAVSLDASE -EMYRTLTRIYWN-GEALSQIPPFIQAASKQGAVNR-SRSEVVLVNAPSGD-YVFCVITKN -QEDEDNAGYVLLRNISRLLWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Cyclobacterium halophilum TaxID=1416801 RepID=A0A1H6T4C9_9BACT ----FTQKLEEEMANFGGETGLYVEHLASGEIF-AIRADSLFPTASVIKVPIMVGIFKQIH -EKKLELDTALLYRDSIRYGGSGLMQYFKDSTTDLATLLSLMIGYSDNTASLWCQELAGGG -QEINKLLDSLGLEHTRVNSRTAGRQEAWEKYGWGQTSPREMVSLLRMIRHEELFSPELSQ -KMYRLMSNVIY-DNYALSAIPPYIQTASKQGMVSS-SRSELVMVNGPSGD-YVFYIATKN -NRDEDNEAYRLQRKLSGMLWNYf ->[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Rhodococcus sp. MTM3W5.2 TaxID=1805827 RepID=A0A1P8YG19_9NOCA ----------------------------DDDVV-SVGADELVVTASVYKLPLVVALCRAFD -AGSLSPTARVRINPADCTPPTGVSTFRDPVVMSWRDLALSMMTVSDNAAADLILGRV-GL -DGIDRVLAELGLTRTRIIGGTADVHRAYDPAFTSATTPREMTSLLDAIWTDRAVSAVQGE -FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAVFTRA -ARADLPVVDRAIGRAAHIAVT-- ->[subseq from] Beta lactamase n=1 Tax=Kutzneria sp. 744 TaxID=345341 RepID=W7SXL8_9PSEU ---SVAARISAVFRSAGAQGFLHAREVGDGPEI-CLGADDPVVLASVFKVPVAVAYAREVA -AGRLDENERTTVTSRYRVGGIGTAGCADDVTMTWRDLALFMMTMSDNAATDVIFHRV-GQ -AAVDQVLADLALHRTRLIGCCEDLTGVLDPTRTTASTPRDITTLLDAIWTDVAGPPEACE -LVRDIMSRQIW-PHRLGSGFESDVEIAAKTGSLP-AIRNEAGVVTYPDGRRYAVAVFTRA -DSGRQPKVDAAIGRAARLAVDE- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. BS55D TaxID=2055943 RepID=UPI00103AA83A ---ALSQRWQELASQKDLQVSAFLLLLDDGRYA-QLNPDTALPAASSIKTPILLVALELLD -AGTLSWNEPLTLTKTTVGGGAGWMASPIGTRFPTHEVATEMIRVSDNSATNLLIERVGGK -EELNARFNALGLSATAVNNWLPDLEGT------NTTSARDLARSIALVDTGETLGPRSRD -LFREVMGTSRT-NRLLPGGLLEGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFVVKG -PF-NDPRSTELIREMAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus hitonicola TaxID=435880 RepID=A0A1I2T1C5_9BACT ---SLQQKLELIARDFKGELGIYVKNLNTQESA-QINSDSIFPTASIVKIPILLGIFEKIE -KEELQFHQSLIYRDSIKYGGSGLMQFFNDSTTDLRTLVALMLSYSDNTTSLWLQGLAGGG -ESINPLLEKWGVQHTRINSRTPGREKDWEIYGWGQTTPKEMAQLLEGIYKGTIFGRSSSE -QMTRLLSNSYY-TEYALSQIPPTINVLSKQGMVN-ASRSEVLLVNSPAGD-YVLSFFTKN -NEDEDNEAWKLSRKVSHEVWNHf ->[subseq from] Uncharacterized protein n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=A0A271JEY3_9BACT ---ALQARLDALADGFNGVVGVYLRHLPTGREA-ALRPDDLFPTASIVKVPILVGVFEQIE -AGTLALDTELTFRDSLRYGDSGFAQLRDSSTVYLHSAVEQMLAASDNTASLWLQGMV-TG -EAINAWLAAEGFEGTRVNSRTAGRRGDWERYGWGQTTPREMAELVRRIVDGEAVSPAADL -EMHRLLTRTHY-DDEAIAALPPSVQVASKQGAVSQ-SRSEVLYVHAPSG-PYLLMVVTKE -QAAPDNAGYDLIRAVSRLAWETf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358ECH6_9BACT --dSLQSRIAARLDGLDAISSIYAKHIPTGREI-AVRADLPMNTLSVIKIPVMIQAFQDNA -SGRLDLGERYTVGPNDMRRGSGLIQTFEHGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -DRVNALLQEEGFSQTRLKATTGDLFRTFEGDSTGRTTAREMASLLEQILNAELADEEASA -EMISILTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ -NTGDFFDLEATLGLIAEDIVEAw ->[subseq from] serine hydrolase n=1 Tax=Rubrivirga sp. SAORIC476 TaxID=1961794 RepID=UPI000BA8F949 ---ALQARLDALADGFNGVVGVYLRHLPTGREA-ALRPDDLFPTASIVKVPILVGVFEQIE -AGTLALDTELTFRDSLRYGDSGFAQLRDSSTVYLHSAVEQMLAASDNTASLWLQGMV-TG -EAINAWLAAEGFEGTRVNSRTAGRRGDWERYGWGQTTPREMAELVRRIVDGEAVSPAADL -EMHRLLTRTHY-DDEAIAALPPSVQVASKQGAVSQ-SRSEVLYVHAPSG-PYLLMVVTKE -QAAPDNAGYDLIRAVSRLAWETf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-337 TaxID=1463900 RepID=UPI0004C535AF -----PARIRAAFAEAGVTGWLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHQLAA -AGALDLGEHIECPSAGRTPGPTGLAAMLDPVMSVRDVAYLMMAVSDNAAADLLLGRV-GL -DAVNRTTRRLGLTGTHAVHTFGELFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA -AIRRILGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HDK6_9BACT --eELESRIRAQLDALDARTALYAKNLPTGREV-AIRADEPMNTLSVIKLTALVQAYREAE -AGRLELDARHPILPEDLRRGSGILQTFDPGLPTFRDLLTQMIITSDNTATDIVAERL-GL -DRVNAFLESEGFQETRFRMTTGDLFRALEGDSTGRSTARETGRLLEGIHEGTWTSRENSE -EMLAILRRQLS-SSRLPRYVGFEASVAHKTGDWPPFGGSDVGILFHEGG-PTVVAIYTGQ -NRGDFVELERKLGRIAVELVQG- ->[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes TaxID=976 RepID=A0A1V0DG10_9BACT ---ALQARLEHLVEGFRGDVGIYVRHLPTGREA-AIQPDTLFPTASLIKVPILLKTFDAIE -QGMLDYHQPLVYRDSLYYPGEDLIGALKDSSIALSKVVMLMITTSDNTGSLWLQGLVGGG -TAINDWLAAHGFEHTRVNSRTPGREAAREVYGWGQTTPREMAEMLVMIREGRAVSPAASE -EMYRVLTRIYW-NDEALSQLPPTVQAASKQGAVSR-SRSEVVLVNAPHGD-YVFTVITKN -QETHDNEGYVLLRDVSRLLWQYf ->[subseq from] Serine hydrolase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A4Z0VWY0_9ACTN -----RDRIRAAFAEAGVTGWLHATDIDSGAQL-EVDADHPVVTASVHKLCLLVALHQRAE -AGHLDLAEQTECRPEGRTPGPTGLAAMLDTALSLRDAAYLMMSVSDNAAADLLLARV-GL -DTVNESTRKLGLAHTHAAHTFGEFLAALDPARTNRSTPRDMTRLLRAVWRDEACSPRHGA -AIRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVVEYPDHGRYAVAVFTRA -ASPSLPAADAVIGTAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A2Z5JRF9_STRAR ----------------------HALDIDSGAQL-GVEADQLVCTASVHKLCLLVALYDRAA -AGDLDLTEQVECSSDPRTPPTGLAAMLDAARLSLRDLAYLMMAVSDNAAADLLLARI-GL -DAVNGATARLGLDATRAVHTFGAMLAALDPARSNRSTPRDMTRLLRAVWRDEACLPEHGA -AIRRVMGLQVW-PHRLASGFPDDVLVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ARATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=2 Tax=Gemmatimonas aurantiaca TaxID=173480 RepID=A0A3D4V9D5_9BACT ---SLRRVIDSLADAHRGVVGYSITNLETGEHL-ERRGDETFTTASLIKVPVLVALFDLAE -QKQLTLDDPIVLTEIDKVGGAGQLQFLRTPLLRLWDVAWLMTTLSDNTATNLVLDRI-KI -RRVWQKMEALGLPHTKVHSGSMTRIGTVAPDSSGVTTPNEMARLFTLLAQGKAVSPSADS -TMLAILARNVDDAKLLRYAY--GVRAAHKTGDVDN-ARTDCGVLYLPAR--VVACVLTKE -NVDTDAEGNTVIGRIGAAIVAHw ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-5123 TaxID=1463856 RepID=UPI000694D63E ---TVEERVTRVFAEAGATVRLHAVDLHSDREV-GVAADEQVVLASVFKILLVLEFARQAG -AGQIDPRERVVLTAADRLGGWGVAGCADDVTMSLRDLAYFTMSVSDNTAADALLRRV-GP -DTVRLLAAELGLGRTRVLGGPRELLEALDPARTTSGTARDVTTLLRLVWQDRAGPAAACA -WVRELMSRQAF-RHRLASGFPDDVRVAAKTGTLP-GHHIEAGVVHYPDGGRYAVAVFAGT -VGPFQVAVDRAIGRAARVAVE-- ->[subseq from] Beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain WH7803) TaxID=32051 RepID=A5GM59_SYNPW ---ALSDRWKQLAAGQDLTVSAFMLVLDDGRYA-QLAPDTALPAASSIKTPILLVTLEELD -AGKLSWNEPLQLSKAVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGK -EALNARFNALGLSATAVNNWLPDLKGT------NTTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSVT-NTLLPKGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A6A0IDT8_9BACT ---ELSARLEALARGSGGRMGFVALHLESGRRY-ERLADEVFEGASVVKLALLVEAVARHR -EGTLDLSDRFPLTPQATAAGSGILDELQPGLPTYRDLLRLMITYSDNTAANVFVDRF-GA -AAVNSRMERLGFAGIRLGGRIPDREPRWKGLRLGWMTPRDTVELYRRIAERSLVDPEASR -LLLELLAWPKSLDRLFRTFRDEGVSWAGKSGTMR-GIRGDSGILTTRKGT-FVLAAFVDG -VDDDGPRANTAMAEAAREVVESw ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter mishustinae TaxID=270918 RepID=A0A0Q9ZBJ1_9FLAO ---ALQQKLEALVNDFKGDVGIYVKNLETDKEI-AINADTIFPTASIVKVPILVKIFDKIE -KGELNYNDTMVYSTDRIYGGSGLMQFYKDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -EAINELMDEIGLEHTRVNSRTDGREKDWEKYGWGQTTPREMASILIEIRNRELISPAASD -EMYRLLGNSFY-QEYALSQIPPYVQAAAKQGMVNK-SRSELFMVNAPSGD-YVGYIATKN -NKEEGNEAWELQRKISALLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. Root147 TaxID=1736468 RepID=A0A0Q9G248_9BACI -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTINVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKEIDNYTCASDVVKCLREIYEGNFLQKSSRE -KIMRMLKMQKF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRVNET-YYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. 5K110 TaxID=2578104 RepID=A0A5R8LCQ2_9MICO --eDIQAEIARIADEFSGEISVAATNLRTGEHV-EFNSREAFPASSVIKVPILVTLFHRAE -RGAVHLDRRLTMHEEDRVPGSGVLKLLSGGLLTVADAAALMIAVSDNTAANLVIDQLGGI -AEVNRAMTELGLHSIRLKNRLDFDVIGRDIAHLGVASTNDLDTLAQAIAHRTAFSPAVSE -ACEKLLSQQQYLDQVLRYVSVAPVVSASKTGFYP-GVRNDMGIVRFRGT-GFTYAACTRG -SDAPEDEGEVTNGRIGHLLLRH- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536HRQ3_9CHLR ---ELVQHLDQLVGSFPGGAGLWIADPNASKPLySHDADEPIITASLYKLAVLAEAERRVD -AGQLHYSDIITIENEDITEDGSF--EVAGTELTLDQALEAMVTISDNGAALALWHVL-GA -DNINATLRNVGINDFHVFV--------AYGEDDNIATPRAIGTLLTLLAKRQLISAAASD -RMLARLERQQI-NDRLPAELPEGVVVAHKTGNLP-GLTHDAGIIYTPSGP-RVVVAMTWD -AY--EADAYAFIANVGSIVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7HDA8_9BACT ---ALRNKLDSIADAHHGIVGYSVIDLESGARI-SRRGDETFPTASLIKVAILVTVYDLVA -KGQLSLDDPLTVLKIDQVPGSGVIQFHNGTVLTVHDAAWLMSTISDNTATNLLLDRV-II -RRVWAKMDSLGLQHTRVHSKSFLRISSSVKYGLGVTTPNEMAHLFELMAQGKAVNPSADS -AMLDILEHNTN-DMMLQRYLI-GARAAHKDGETDE-VRTECTLWYLRNR--VAACVMTKE -NKDQDNEPQLTMANMGLAIVNA- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces alboviridis TaxID=67269 RepID=UPI000515CFE8 ------RTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTAFCRLAD -AGRIDPSHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP -EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPASCS -FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Algoriphagus resistens TaxID=1750590 RepID=UPI0007168F78 --nKLESAIQDLVASFHGDIGIYLEHLPSGNTI-EINSDTIFPTASIVKLPILLGVFDKIE -KGELHYHESLMYRDSIKYGGSGIMQFFKDSTTDLSTLLALMLSYSDNTTSLWNQSLAGGG -IQINQVMDQLGYKTTRVNSRTEGRERSWEKYGWGQTTPKEMADILVRLNAGELISTAASE -LMYRLLSNTFY-TDYAISGIPPGINVASKQGMVN-ASRSEVFLVNSPQGD-YVCAVFTKN -NVDQDNEAWILTRKLSNLIWNYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00064CAC3A -------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLTIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter xylinus TaxID=28448 RepID=A0A318PF13_KOMXY ---SLSDEVAATVAGQPGHFAVYAALSGQRPEV-CLHCTDYINAASTMKLFVLDAAYDMFA -RGTLHPQDRIVVKNQSLVGSRSFAYAQSGQPVAVAELLRVMIQYSSNLATNLLIERV-GV -PYIRAVIRTQHIKGVRFGRMIEDFDAN-ARGIHNQMTAKGLGLFMQKLDHGEIVGPEQSR -AMIDILRGQTF-NDMIPPGLPSGTPVAHKTGWVD-GVRNDAGIVFLPDGQHYILVMLSRS -LP-DEAAGVRVLNTVSRQVYDHf ->[subseq from] Serine hydrolase n=1 Tax=Muribaculaceae bacterium TaxID=2498093 RepID=A0A4S4H7Z8_9BACT ----LRQDISGFVEKQHGKIGVAVI-TDRKDTL-TVNNTPDFPLMSMFKLHQSIAICRNFG -ENGIGLDSVLNIKQCEMNKWSPMLKNNMDKDIPVSGLLEYILVHSDNNASNLLFNRVVSV -AETDSIVASLPDRGFRLMYNEYEMLQDKSLSYKNVSSPLAYALMIDKLFTDSLMPHSMQA -FVKQAMYNCETGMGRIAAPLAPGVAFAHRTGSGYVNAVNDGGYVTLPSGQSYSIAVFVKD -FAGTQDEAESVIAKISELVYN-- ->[subseq from] Beta-lactamase class A n=2 Tax=Actinomadura madurae TaxID=1993 RepID=A0A1I5CVG9_9ACTN --------IEAEFRAAGVTGFLHVVDMDTGREV-AVGADEPVVLASVFKVPLLVAFHRQAA -RGLLDPAEQVTLRPDDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADVIMDRV-GR -EAVNATAAELGLDGTVIEVDGRELHEALDPLRTSRSTPRDMTRLLSMVWRDEAAPAGGCA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS -LLAVLPEADAVIGTAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=A0A1Q4YVM3_9ACTN -------------AEAGVTGWLHAVDIDSGAQI-DAGADRPVVTASVHKLCLLVALHQQAE -AGRLVLTEQTECPRDGRTAPTGLAAMLDAARVSLRDAAYLMVAVSDNTAADLLLERV-GL -DAVNDTTRRLGLTRTHATQTFREFLAAVDPARTNRSTPRDMTRLLGAIWRDEACTPEHGA -AIRRLLGLQVW-PHRLASGFPDDVLVAGKTGSAPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02414 TaxID=1703922 RepID=A0A1Q5CTI7_9ACTN ----TAARLGAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKVCVLVTLHELAA -AGEIDLTERVECPPAGRTPGPTGLAAMLDPVLSLRDAALLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGALWRDETCPAEYGA -AMRRVMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=5 Tax=Streptomyces TaxID=1883 RepID=A0A1H2BZB7_9ACTN -----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. C1-24 TaxID=2495913 RepID=A0A5A7S6T4_9NOCA ---QVEKRIRDVFADAGCTGWLHARRLDSHSAQlSVDGDQLVVTASVYKLPLMVALCRCFD -AGEIDPLEQVRVVPAQCTPPTGISIFRDPVTLSWRDLATSMIVVSDNSAADIVLGRV-GL -TRVDETIAALGLARTRVVGGTAAVHAAYDPSYASATTPREMNDLLGAIWSGAMLSATQTA -YVKDVLGKQLW-QHRIRSGFPGGVEVAGKTGTIGI-IRNEVAVVTFPGESPVAVAVFTRA -ARADLPAVDAAIGEVARIAVS-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=UPI000B9E3D1E -----LTRIREAFDGAGVTGRLHALDIDSGAEV-GASADHPVVTASVHKLCLLVALHQQAA -AGRVDLTEQIECPPAGRTSGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAADLLLERV-GL -DAVNHTTARLGLAHTHAVYTFGETFGALDPARTNHSTPRDMTRLLAAIWRDEACAPAHAA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -TNATFPPADAVIGTTARIAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Parafilimonas terrae TaxID=1465490 RepID=A0A1I5Z9H0_9BACT ---KLQQQITELIKDFHGDIGIYVHDLKHHKTV-SINADTVFPTASIVKISILAGIMNKIQ -HGELDYHQRLLYTDSLYYSGDDILSNFKDSSIELSKVMMLMLTISDNCASLWLQGLAGGG -LTINALLDSLGYKNTRVNSRTPGRETYRSQYGWGQTTPREIATIMNDIVDKKIISTEASE -KMLRLLGRQYW-DEEALSQIPAGIFTADKNGAVDE-SRNEVLYVNCK--NPYIFSIFTKN -NKNADNEAWVLTRKLSALLWKHf ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus acidophilus (strain ATCC 700253 / DSM 10332 / NAL) TaxID=679936 RepID=G8TU74_SULAD --qTLDNELMAVQREFSGRYAVYAEHLGTGETV-SFGDQTAWETASVMKLPILTEALRQCQ -EGVHALTEPVEYRRDDGVPGSGVLQYLTPGVLPFKDVLTLMVIVSDNVATNMVLRTI-GI -EAVNQTCHDMGLMQTRVMRRIDFS----SPDPLGLSSPFDLVQLLKSLYFNTVLDSRHAG -IAVEILRHQQY-QTLLTRYLPYDVTVASKSGSLT-GIRNDAGLVISPWGD-YAVAIMSEA -SKDRDTEAFQVLPRVSRAIFDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Algoriphagus zhangzhouensis TaxID=1073327 RepID=A0A1M7ZHC4_9BACT ---GLEKEIQSLVEGFHGDVGIYIQELGNDRKI-EINADTVFSTASIVKIPIMLGIFDKIE -KDELSFHQALMYRDSIKYGGSGLMQFFQDSTTDLRTLIALMLSYSDNTTSLWNQALAGGG -TQINELMEKLGYTNTRVNSRTPGREKIWEKYGWGQTSPKEMADILVRIYQKELITPAASE -QMYRLLSNTYY-NDYALSQIPPGVNVASKQGMVN-ASRSEVFLVNGPESD-FVVAIFTDH -NEDTDNEAWELTRKITLLVWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Phormidesmis priestleyi Ana TaxID=1666911 RepID=A0A0N8KNG7_9CYAN ----LKAALQDLPNRYNLTPKAFYIDVDTGDYV-SLDGGDTIAAASTIKLPILLAFFEEVD -AGRITTNQMLELLPHQVAEGSGGMQFAPGTQFTALEVATQMIVDSDNTATNMMIDLLGGM -AALNERFKGYGLAKTQISASLPDLPGD------NTTSAKDLVNTM-LLISGDRLTLRSRD -RILNILNRTYN-KDLLADGMEKEALTYNKTGDIES-VLGDVALVDLANGKRYVVAVLVER -PSND-GRAVDLIHTISERIYK-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia brevicatena TaxID=37327 RepID=UPI0002EBF803 ----VEDRIRAVFADAGCTGWLHARRCDSDDEV-SVAGYDRVVTASTYKLVLLLAFCHAVD -TGRIDPREPVTVIPAECTPPTGISALRDPVTMSRRDLATSMMTVSDNAAADLLLDEV-GL -GAVEALLTRVGLAGTRIVGGTADVHRAYDPAFTSSSTPEEMTRLLLAVWTGAVVSVEQTG -FVRAVMRSQVW-PHRIASAFPRGVTVAGKTGTIGV-IRNEVAVVEFPGEYPVAVAVFTRA -ARADLPVVDAAIAESARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura meyerae TaxID=240840 RepID=A0A239JA14_9ACTN -------RIEAEFRSAGVTGWLHVADIDTGRDV-AVGAAEPVVLASVFKLPLLVAFHRQAA -TGVLDPAEQVTLRPQDRTAPTGVSALLDEVRMSLRDLTCLMITVSDNAAADTVLDRVGGR -DAVNEAAAALGLRDTVVEVTGRELHEALDPARTSRSTPRDMTRLVSLIWRDEAAPAADCA -AMRRLLGLQVW-PHRLSSGFPDDVQVSGKTGTLLT-VRNEVGAVEYPDGARYAVAIFTRS -LLAVLPRADAVIGTTARLAIE-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HUG9_9CHLR --nALRDSLDSAVTEFNGTAAVVVSGVDTNFRY-AKNDDAVFPSASLYKLEVMVEAYRQVA -AGRISLDDTVTVNWDDMSV-DP-SDTLPGTTLSVRDAIERMITISDNGPAHALTRLL-DP -HNVNATTLSVGMKDTRINAALPADE---QLAEDNTTSARDMERLFSGLATGKIVSPDASA -EMLAVLFRQQL-NDRLPSGLPADAAIAHKTGDLIQ-VAHDAGLLLTPFG-PRVVVVLTSD -FS-DYDEVSRLMARVAAAAYT-- ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter nutrimenti TaxID=1241337 RepID=A0A318UKM8_9SPHI ----LSGMLTELTRGFQGQVGIYVKNLKTGKSA-GFNADSIFPTASMVKVPITSGVFNKIV -HKELDYRSTLIYKDSLLYAGEDILGSFKNNEIALSKVLMLMITTSDNTASLWCQSLAGGG -TAINKLMEENGLQFTRVNSRTPGREANRKQYGWGQTTPREMATLLSLIRQGKLISPAASE -RIYRNLIRIYF-DQVALSEIPPYIQVASKSGAVDE-ARSEVALVNAPHGD-YVFCITTKN -QKNSSNEGWALIRKLSSMLWNYf ->[subseq from] Beta-lactamase n=1 Tax=Clostridia bacterium 62_21 TaxID=1635276 RepID=A0A101FPT1_9FIRM --nALLSRLVDVLQNEKGTYGVYLLDLKSGHWL-GINHEEPFHAASTFKLPANLYLYEQIA -AGRISPQTVLTYRKEHYEAGTGLLQYRPVGSFTIATLARYSIVYSDNVANNILISYV-GK -QNVKNYMRNLGGKL--------------VSDTQNVTCPRDMAAYTLHLLKFASEHPEQGN -ALLDLLENTVF-NDRISKPLP--VKVAHKIGNWPTGTYNDVGYVKHPEN-PYVIAVFSKY -TP-GKERACQVIQTISRLVYNY- ->[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-886 TaxID=2682776 RepID=UPI00140E7616 ---NLAATVSGIISSYGANASVTLSDLDDYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN -SGYLALEDSYTVQESDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM -DAVNEEAVKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ -LATDFLSQQTD-AGGIAPSLSSGETFAHKTGTLTN-VRHDAGIVQ--GEAPYVLSVFVEG -TDEG--SALSLMGEVT------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. VT-16-64 TaxID=1917019 RepID=A0A1V2SA09_9BACI ---SYKRHIETLAQEASGKTAVYICTPDG--EI-KINEAERMQAASVIKVPIVMAGLHASD -QGMLDLNKKVVVQ--DKVAGTGVLNYLSGNMLSILNMMTLALIVSDNTASNLLIHEI-GR -ENINAFCQKAGASQTVLGRYFMDH-EAMERGIDNYTSAGDMIRFFRLIGHNKLLSNESRK -VIYQMLENQQFREKLAQAMFHDKVSIANKTGELN-GIQHDVGMFTFENRQ-VYAAILSSN -WN-NNYQGREFISQIGKLTIEY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG09_land_8_20_14_0_10_38_17 TaxID=1974884 RepID=A0A2H0WQS9_9BACT ---SIEKDLWQLVAPAKGVYGICIVDLGKGNTS-GINKDEIFPAASLIKLPLIYAFYQQVE -LGKIDPNEQYSLKEGDKIEGTGSVYQQPAGTYTLRQLAALMGKQSDNTAQNILAKIL-GE -EKIQAAIVDLGMEKTSYLDWE--------------TSPKDIAIFWQKLATGQTLTTAHRQ -EILDFLTNTIF-EEQIPAGLPEGIKVAHKIGMDE-GVLHDAGIVFAD--QPFILVLMSKG -VDL--DEAKQILPKITERVWE-- ->[subseq from] Uncharacterized protein n=1 Tax=Rickettsiales bacterium TaxID=2026788 RepID=A0A2D6ZZS8_9RICK ----LSSEIKRIVAYQPQSVFFAAYHLESGKFL-NINGDLTFPMASLVKTFIACTYLDLVD -EKKIDPDKKISIARENLRPYSIFSKLFIRPNISLNNLLEAMMIYSENSATDILFHEIGGI -KAINGFLKKNKLKGITVSRSILELISIFFSNTKDSSTALAYQKFLIEFQNGGLLSPSSTN -YLKKIMKKNIHGKYRLKGFLPKN-SFMHKTGSLSM-LTNDAGIFELPKNGHLILVSVLER -KPYRMPDSNEFI----------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=A0A6B3QLM9_STRTE ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDTAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVYGFGEMLRALDPARTNRSTPRDMTRLLGAVWRDEACPAEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus alkalitolerans TaxID=1550385 RepID=UPI0013D0D432 ----LSTGLTEEIKKCPGQMSIMLEV--DNHTF-EWESDRKITSASLIKLPILLEGFKQIE -LGKWNLSEAIQILESQKVEGAGVIQALSTAELSVHDLLTLMIIVSDNTATNILIDLF-DM -EQINAFIKDSGCVSTELNRKMMDFK-AIEKGINNWTTSREMMLMLQEIDNGSRFSSKSRD -YMKGILHNQQL-LDKLPLFIDKGW-IGNKTGELP-GIEHDCAIMKVGGRT-AYISVLCDD -LP-SKGKGKIAIANIGELVWKY- ->[subseq from] D-alanyl-D-alanine carboxypeptidase DacB n=1 Tax=Oceanobacillus picturae TaxID=171693 RepID=A0A0U9HBJ2_9BACI --------------------QYSVLLTSGEGSL-AINEQQLRPAASLAKIPILIEACQQIE -SGRLHPDKLVYIEEEQFVGGSGIISHLTNSHYSYMNLIELMVIVSDNTAANVLLESL-GM -GAVNQTIEQLGAKNTVINRKFMDTKAQ-QEGLENYTTALDMVTLLKAISEEEYISSKSRK -FMRSILAKQQL-TNKLANFLHPSVTIFHKTGELC-GIEHDAAILECKEER-AYITVLSDH -LP-SNAEGQHTIAQIGKHAIDY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gastranaerophilus sp. (ex Termes propinquus) TaxID=2029980 RepID=A0A2L2X499_9BACT --------LAHAKQHSHLSPSIYIWDYSSGRSV-EIDSEAPVSAASIIKIPILFEFFRQIE -DKNANLSTKVKFEELYRTSGSGDMQYLKSGGYTFDYLANKMITESDNTATNIILDYIGGA -QGMNRALRGWGLENSYMSNWLPDLRGT------NRMSAKDVASVLYNLDNPSFLSAVHKE -QIKEYMGNVKN-RSLLRAGLPDEAILLHKTGDIGT-MLGDAGVVLRSDGRKYIIVVMAKR -PFND-YSAREFVKETSALVYK-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED90 TaxID=1986600 RepID=A0A1Z9W7G5_9SYNE ---ALSERWKQLAAGEDLTVSAFMLVLDDGRYA-QLAPDTALPAASAIKTPILLVTLEELD -AGKLSWNEPLTLTKPVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGK -DALNARFNTLGLSATAVNNWLPDLKGT------NTTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSVT-NTLLPKGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P2415 TaxID=1805471 RepID=UPI0009884A85 ---------IRKLERLPGKISFLYENLETGDVI-SYHEKEPVMAASVIKLFVMAAIFERME -QGLLDPEKIFSIKREDCVPCGALTYLHDGILVTAMDLVTLMIIFSDNTAANVLIDYL-GM -EQINGTIKALGFEQTLLQRKMYDVLRS-RRGIQNYITAFETGRLFKMMYDGTLISRQASD -KMISILKNQQL-CSKIPQALPEEPEIAHKTGEDT-GITHDAGIIYGK--KPFLVC-FCGN -ET-DTPAFERVMAEIS------- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A4Q3B450_9SPHI --qKLQLKLNELVKGFKGDVGIYVKNLKTGKTA-SINADTIFPTASMIKVPITCGVFNKIE -KGELDYHAQLMYCDSLLYAGEDILGSFKDSEISLSKVLMLMITTSDNTASLWAQLLAGTG -TAINEVMANNGLKDTRVNSRTPGRKDNQKKYGWGQTTPKEMATLLALIRDGKMINPAASE -RIYRNLIRIYW-DSEALSQIPPTVQVASKSGAVD-AARSEVCLVNAPHGD-YVFCITTKN -QQNYSNEGWTMIRKLSNLLWNHy ->[subseq from] serine hydrolase n=1 Tax=Nocardia abscessus TaxID=120957 RepID=UPI00030227BC ---------QEIFRTAGVEGWVYARCVGCGAEA-GSGADEPVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRARAADRLGGVGTAGCADDVEFSLRDAAYLALTVSDNTAADLLFDRV-GL -DNVRSLLRELGLTATRVVGPPRAVVRALDPGRTTASTPREMARLLTLIALDQAGAPEACR -WVRDLMRQQVN-WYRLAAAFPPEVQVWAKTGTLP-GVRNEIGVVEYPDRTRYAVAVFTRA -ATQRLPEVDRAIGAAA------- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Gastranaerophilus sp. (ex Termes propinquus) TaxID=2029980 RepID=UPI000CE9CF20 --------LAHAKQHSHLSPSIYIWDYSSGRSV-EIDSEAPVSAASIIKIPILFEFFRQIE -DKNANLSTKVKFEELYRTSGSGDMQYLKSGGYTFDYLANKMITESDNTATNIILDYIGGA -QGMNRALRGWGLENSYMSNWLPDLRGT------NRMSAKDVASVLYNLDNPSFLSAVHKE -QIKEYMGNVKN-RSLLRAGLPDEAILLHKTGDIGT-MLGDAGVVLRSDGRKYIIVVMAKR -PFND-YSAREFVKETSALVYK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-109 TaxID=1913101 RepID=A0A542PDW2_9ACTN ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGDLDLTEQVECPPAGRTPPTGLAAMRDPVRLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DTVNRTSARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLAALWRDEACPAEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A2E7DIE4_9GAMM --dKMQSDLEAIIDDYEGVAGVHVIDLSSGYRW-AYRDKLVFPQASAIKIPILLELFRRAE -SDPELLGRRVEMTDEVRTAGSGVLQVLTHGGLSLEDYAIYMILHSDNTATNVLIEQL-GM -EAVNKLSASLGASKTLLQRKMIRPEQSLS-GNENLSTPQEAALIMEKIESCDLMSQQGCD -RVRSILELYKD--GAIRNPIPREVPIAFKPGGIT-GVSTVWGIVDVPDR-PYVLTVMSNY -GG----NGGEVIEKISAVTYNFf ->[subseq from] Serine hydrolase n=1 Tax=Kyrpidia spormannii TaxID=2055160 RepID=A0A2K8N9W0_9BACL --tALKQAINGYITSQPGTYGVVVVDLDSGAKL-DIDGNRVFFAASTFKLPMNLYLYTLIA -QGKVDPNTKLIYEASDYEDGTGIASTPVGTEYTIRELSQASIVASDNVATNILLDDL-GV -DNVKAFMRQLGGKEV--------------VDGDNVTTPDDMALYAVKLFEFVKKNPTVAA -PLIDDLEHTDF-NDRIPAKLPKGVPVAHKIGNWTD-QWHDVGIVFLSGR-PYVISLFSRD -IDQD--TAAQVLSTVSRMVYDY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ScaeMP-e48 TaxID=1100823 RepID=UPI000823CF6C -----ERTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTAFCRLAD -AGRIDPSHRLTLGAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP -EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPASCS -FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Chloracidobacterium sp. CP2_5A TaxID=2012633 RepID=A0A257B752_9BACT ---EMARRLRRRLASFKGKVFCFAKNLDTGETF-GLAPDAKVRTASTIKVPIMVEVFAQVA -EGKLAWDDKLAIVRRHEYEGGVLFELTPGTQITVRDAMRLMIVVSDNIATNILLDRI-TT -DAVNARLAQMGFESIRSLRKIAGGGEENQKYGIGVATSREMVKLLETLERGAAVSPEASR -EMLAVMKRQQY-RDGIGRRLR-GVEVANKPGALDH-LRSDIGIVYTKRG-RIAMAITVED -LPCSEAEGHLLIADI-------- ->[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI001362DB94 --eELRQAIERQRAVCSGESAVIVKNLTTGERI-ACNERDVFPAASLIKLPVLFTLYKRKK --EGFFLGERIRMEQGHKVGGFGILKDEPGLTLSWKDLAVLMIIVSDNTAANWLIDFL-GM -DAVNREIKALGLSETELNRKMMDAAA-KEMGLENRTSAADMERMFEAV-----LKDADSE -EMMDILKRQQC-NNKLPVFFGEHGGFAHKTGDLP-GTEHDAGILFTGNQA-FFTAVLTRD -LR-DNRDGIRLNQEIGRLVYHY- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma lacussanchae TaxID=1884249 RepID=UPI001108E124 --sTLEKRLHTALTGFRGDVGIYVRNLRTGQTV-SINADTLFPTASTIKVPIQCGLFDKIH -QGALTYGQVLTYKDSLRYGDDIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG -AAINAWLDKNGFPQTRVNSRTPGRKGDWSQYGWGQTTPRELANLLVYIREGKAVSPDASD -EMYRNLGRQYW-DNDGLSQLPPEIKTASKNGAVDR-SRSEVVLVHAPHGD-YVYCVMTKN -QKERSNEGFTLLRNVSAILWQHf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI0006E32A2D -----RDRIRAAFAEAGVTGWLHATDIDSGAQL-EVDADHPVVTASVHKLCLLVALHQRAE -AGHLDLAEQTECRPEGRTPGPTGLAAMLDTALSLRDAAYLMMSVSDNAAADLLLARV-GL -DTVNESTRKLGLARTHAAHTFGEFLAALDPARTNRSTPRDMTRLLRAVWRDEACSPRHGA -AIRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVVEYPDHGRYAVAVFTRA -ASPSLPAADAVIGTAARIAVE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Chitinophaga sp. OK723 TaxID=2135605 RepID=A0A4R7CEP9_9BACT --kRLTAILAPLLTAFNGQAGIYVHHLKTDRIV-AINADTTFPTASMIKTAIQVGIFNKLA -KGELQYHQNLVYRDSLLYKGEDILGSFRDSEIALDKVMMLMLTMSDNTASLWLQSLAGGG -GVINQWLQEHGFEHLRVNSRTKGREANRQEYGWGQTSPREMARLLEMIYKGEVISAAASE -RMYRNLTRNYW-DQEGLTQVPTNVRTASKNGAVDE-SRSEVIMVNAPHGD-YVYCIITKN -NKNHDNEAWQLLRKVGFAIWQYy ->[subseq from] Beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain RCC307) TaxID=316278 RepID=A5GRX5_SYNR3 --qALSRRLAEIAAQKDLKVGAFVLVLDDGTFA-QLHPDRPLSAASSIKTPILLVAFEALD -QAKLSLNEALSLNKTVVGGGAGWMGSQPGSQFSIFEVATEMIRVSDNTATNLLIQRLGGK -DSLNARFIELGLEGTVINNWLPDLKGT------NTTTPRDQARAIALVETGQTLSARSRD -LFRQTLGTSRT-DTLIPRGWLRGVRVYNKTGDIGI-AYVDSALVELPDGRRVVASYMVEG -PFND-PRSTNMIRALAAA----- ->[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ350 TaxID=2709799 RepID=UPI0013EA657A ---NLAATVSGIISSYGANASVTYTDLDGYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN -SGYLALEDSYTVQDSDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM -DAVNEEAAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILLLIANGEFYTPELSQ -LATDFLSQQTD-AGGIAASLSSGETFAHKTGTLTN-VKHDAGIVQ--GEAPYVLSVFVEG -VDEG--SALSLMGEV-------- ->[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ119 TaxID=2709798 RepID=UPI0013EB7105 ---NLAATVSGIISSYGANASVTYTDLDGYATF-AVDGSEPHVSASMIKLAIMAEVFDQVN -SGYLALEDSYTVQDSDIVGGTGTLQGGPGTQLSLSDLVRHMIAESDNVATNMLIDLV-GM -DAVNEEAAKLGLNATSLQRYMMDTDAQ-AAGIENHMSSDDAAVILILIANGEFYTPELSQ -LATDFLSQQTD-AGGIAASLSSGETFAHKTGTLTN-VKHDAGIVQ--GEAPYVLSVFVEG -VDEG--SALSLMGEV-------- ->[subseq from] Uncharacterized protein n=1 Tax=Flammeovirgaceae bacterium 311 TaxID=1257021 RepID=A0A0D3LJD2_9BACT ----LQQKLERLVKGFRGDVGIYVHHLERGNTA-AIAADSIFPTASMIKVPITIGLFRKIE -TGELDINQPLIYRDSLFYEGEDLLGAFKDSAVKLSKVAMLMITTSDNTASLWAQQLAGTG -TAINGWLQENGYAHTRVNSRTEGRKEAWSTYGWGQTTPREMARLLVQIRQGKVINPAASD -RIYRNLCNIYW-DDVALTQLPPTVQAASKQGSVNQ-TRAEVVLVNAPSGD-YVFCIITKN -QQETDNEGWELIRHVSALLWQHf ->[subseq from] Uncharacterized protein n=2 Tax=Caproiciproducens galactitolivorans TaxID=642589 RepID=A0A4Z0XZ10_9FIRM ---------ENEINNSNANVSLLVHDFTRSQTLlSFHAEQKVVAASTIKTLILLAALEKVQ -KSELELSQMVTVPALEILPDTRVFDRDVR-EYRLEELLTWMIITSDNTATNVLIDLL-GM -DAVNAYCRKLKLESTVLERKMHDWG-AIEQGRNNYTSAINQLTVFAALHRRTILTPKLCD -RALGILKRQRDYSLAFRYIADESLTAAHKTGGLDR-LNHDSGLFYLDGN-VYYFGCFVSE -SMKENPVSKKLIGRLSREVYEYf ->[subseq from] Beta-lactamase n=1 Tax=Deinococcus swuensis TaxID=1182571 RepID=A0A0A7KFV8_9DEIO -------------QGYGGEVGLRICDLVGQELF-ALNAARVFPAASTIKVPLLVLALEWAQ -TGRLRLEDRVTLQAADRVPGAGVLHELGPGLLSWRDVLTLMIVVSDNTATNLLIDLL-GV -ETVNTWLEARGWSQTRLVGGLERRNATQRRGERNCTSALEQTDLLGRLVRGELLDEVHTA -LALDILERQQL-RDVIGPGLPRAYRLASKSGELD-GVHHDVGILYTP--RPLVVALLSEG -GAD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Handelsmanbacteria sp. (strain RIFCSPLOWO2_12_FULL_64_10) TaxID=1817868 RepID=A0A1F6CBM3_HANXR ---QVREPLQNILAQCSGRVGVAAQDLRTGREI-AWRADESFPTASMIKMAVLVELERQAL -AGEQSWEASLRLTPEAKVGGSSLLRRMSDGLLPVYDLAYLMMTVSDNTATNLLIDLV-GL -DRVNRTMADHGLSEIRLNNKIDFSRLWRDPNDFGVGAPRAFCRLMADILEGRLLTPDACL -HMLKLMDGVGA-GERLARYLPYNLHFAGKTGSLT-GVRAHTAALWSEEAVRLAFSVMVAD -STDRDMDGLLTIARIGKLVYDTf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID5910 TaxID=2690312 RepID=UPI00136DE7E6 ---TVTGRLRAAFDEAGVTGWLHAVDIDSGAQV-DAGADQAVCTASVHKLCVLVALHEQAA -AGLLDLTERVECPPAGRTPPTGVAAMLDPVTLSLRDAAFLMMSVSDNAAADLLLDRV-GL -DAVNRTTARLGLTRTRAVSSFGQMLASLDPARANHSTPRDMTRLLAAVWRDEACPPEYGA -AMRRVLGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. KBS0724 TaxID=1179674 RepID=A0A554QYC8_9NOCA ---SAQQEITAVLAEAKTDAFVHARDIDSGEEF-GYGADDGVILASVFKIPVVLEYARAVA -AGTLDPTEHATVTAEFRSGGIGVGGCADDVTASWRDLALLMMSFSDNAATDFIYHRL-GL -DNIVSTLRGLGLEKTNLVRDCRGLFKVMDPARTNSSTPREITALLAAIWRDEAGPASACD -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVSYPDGKRYAVGVFTKS -HEKRAPKIDASIGTVGRIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium TaxID=2044944 RepID=A0A3S0E468_9SPHI --kKLQQKIELLVSGFKGTVGVYIKDIKTGKEA-MYNADTIFPTASIVKVPILLGIMDKIN -KRELEYEQELIYKDSLLYEGEDILGSFKSNEILLKKVMMLMLTTSDNTASLWLQSLAGKG -TRINEILDSLGFISTRVNSRTPGRENNRTQYGWGQSTPKEMALLFEKIYKKEIINEAACD -RMMRCLGRNYWDLNEAISQIPPTIEVFSKNGCVD-ATRNEVLLVNAPHH-PFIMSIFTKN -NEDQDNEAWALARKLAAMLWKYf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Synechococcus TaxID=2626047 RepID=A0A368CIP0_9SYNE --kALSAKLAQLAAQKDLQVGAFALVLDDGSYG-QFKPDLVLPAASAIKTPILLVALEALD -AGKLQLDELLSLNKTVVGGGSGWMGGQPGSQFTVLEVATEMIRVSDNTATNLLIQRLGGK -TALNARFQELGLEGTVINNWLPDLEGT------NTTTARDQARSIALVETAQVLTPRSRD -LFRQTLGTSRT-DTLIPRGWLQGVRTYNKTGDIGI-AYVDSALIELPDGRRAVASYMVRG -PFN-SPRSTNMIRALSGATAAAf ->[subseq from] Serine hydrolase n=1 Tax=Blastocatellia bacterium TaxID=2052146 RepID=A0A317HY46_9BACT ---EMDAQVKKAIAAFKGTVSLYAKNLETGETY-AVNADERVRTASTIKIAVMIEAFARVE -EGKAKWTDEVVLTKEKKVSGSGILFELSDGLLTLRDALNLMMMLSDNTATNLVLDVL-TT -DAVNARMESLGFKQIKILRKVGSGGDSIAGDPENFATPHEWVLVMEKLERGEIVSKAASK -EMIELMKREQA-RYAIGRSLS-DLPMASKYGALDR-LRSAVGIIYSKKGR-IAMAISCDD -M---------------------- ->[subseq from] serine hydrolase n=1 Tax=Cyclobacterium xiamenense TaxID=1297121 RepID=UPI0012B88EF1 ----FTQKLEEEMANFGGETGLYVEHLASGEIF-AIRADSLFPTASVIKVPIMVGIFKQIH -DKKLELDTALLYRDSIRYGGSGLMQYFKDSTTDLATLLSLMIGYSDNTASLWCQELAGGG -QEINKLLDSLGLEHTRVNSRTAGRQEAWEKYGWGQTSPREMVSLLRMIRHEELFSPELSQ -KMYRLMSNVIY-DNYALSAIPPYIQTASKQGMVSS-SRSELVMVNGPSGD-YVFYIATKN -NRDEDNEAYRLQRKLSGMLWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus profundi TaxID=2024555 RepID=A0A2A2IIL5_9BACI ---QLENAIRDLIQNNKHNFSISIHT-QE-GNI-SINAAKQRKAASLAKISILLEAYRQIE -NNKLSLETPIYINKSAMVGGSGVLNYLTNSHHSLQNLLELMIIVSDNTASNLLLEHV-GM -ENINKLTEKTGCKQTIIKRKFMDLQAQ-MVGFENYTSSQDIATLLKIISKNNVLSDKSRH -QMLEILSNQQF-KDKLAAYLTDKIEIYHKSGELQ-GIEHDAAIFKYHEN-TIEVAVLSEG -WI-NNGEGKKYIAAIGKLLIT-- ->[subseq from] Serine hydrolase n=2 Tax=root TaxID=1 RepID=A0A5N9B355_9CHLR ---KLVKSINTQVENFNGVAGVSIKDLTTGWYY-GINDELIFPTASSIKIPILLKLIESSE -ASKLNLLKNIEITEEMKSRGSGVIHKMNGTILTVENLAILMINLSDNTATNLCIDIA-GQ -DEVNKMLEDYEFVSMRLNRKMQDYT-AIKEGRENLSSVKEMNLILEMLDSSRAIKPEVAK -KVLNILSLNKS--TPISQPLPENIIVAGKTGGMP-GVRCETAIIYLANKK-YILTVMTSY -AGNGSSSSNQNI----------- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E8CW33_9PLAN ------AELDATAKKFAGRIGFFVRDIASGADY-GWNSDERFPPASVIKLPVMIELYRQAA -DGRLDLDKKLRLPTDISTHGTGVLKKNDRPVLPLPEYADLMMIHSDNMATDFIIRTV-ST -EATNRFLDAQGFRNTRVSLELGRWHYYSDSLKNNVCAPRETVLLLERLYKGRLTSEKHKE -AILEPMRYSTH-KDTIARHVKDGIQVANKYGGSQR-IAADAGIVEIPDR-PIAIACFALA -KDPADRSGREVLAEMCRLAI--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces celluloflavus TaxID=58344 RepID=UPI00069AEEC1 -----LTRIREAFDGAGVTGRLHALDIDSGAEV-GASADHPVVTASVHKLCLLVALHQQAA -AGRVDLTEQIECPPAGRTPGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAADLLLERV-GL -DAVNHTTARLGLAHTHAVYTFGETFGALDPVRTNHSTPRDMTRLLAAIWRDEACAPAHAA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -TNATFPPADAVIGTTARIAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Lunatimonas lonarensis TaxID=1232681 RepID=R7ZMJ4_9BACT ---TLIETLKRELAGFKGTAGLYALNLQTGEEI-AINADTLFPTASIIKVPILVGVFDKIE -QGELTYNQPLMYRDSLKYGGSGLMQFFQDSTTDLSVLVSLMITYSDNTTSLWCQALAGGG -VAINALMENLGLVHTRVNSRTPGREANREQFGWGQTTPREMAQLLVKIRKGEVVSPKASE -RMYRLMTNIYY-DENALSAIPPYIQTASKQGMVN-ASRSELVMVNAPGGD-YVFYIATKD -NEEEDNESYVLKRTVSRLLWEAw ->[subseq from] serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=UPI0012B7A429 -------------SHMSGKTGFYYKDLATGETA-GFQEKAQFRAASVYKLPLFAGILLLAH -RGEADLFAKVRIAEDEKIPGCGAVQHLTGEPLDVLSLCKLMITISDNTATNALARYF-GI -ERMKPVFRELGLSGTQMNRCLYDLEKE-EQGIQNWIVPEELGGLLEGIHRRTLISPEVSA -YLEEILLQQQI-NHKIPGIMGENVPVAHKTGEED-GTTHDVGIVCAK--RPFVVCFTSNE -TD--VPVFEDFIR---------- ->[subseq from] Beta-lactamase n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A381JQP3_9FIRM --------IIKKLERIPGKISFLYEDLKTGEGF-AYHEQEPMMAASVIKLFVMTAAFEKSK -KGTFQMDKLFPVKREDCVPCGALTYLHDGILVTGLDLVTLMIIFSDNTATNILIDIL-GI -EEINDTIRGLGFRHTLLQRKMYDIERS-SRGIQNYITAYETGRLLKMMYEGTLIDRRSSE -AMISILKNQQL-CSKIPQALGESPEIAHKTGEDM-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEVSLELYK-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A0G0ZAD4_9BACT --eEIEAEISRLTSDSSGTYSVYLEDLNSGRNF-GINEQMVVTAASVNKIPILAALYHKAG -KNEIDLDRIIVPQAKDVQDTGSIRYDAPGTAYSLKTLARLMMEKSDNTAAYILASLVVGL -DDIQNLIESWGLTQTDMK--------------INKTSAKDIAIITIKMYRSEITGKALTA -EMIDFMDDSDF-EDRIPKGIDGNTKVYHKTGDEVR-TVHDAGIVDLPGK-PYFLAVFTTD -IV-DEEATKTKIAQISRIVYEN- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_G6-1 TaxID=1938853 RepID=A0A286CK85_9ACTN -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGLLDLTEQVECSPQARTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADQLLERV-GL -DAVNRTTARLGLARTLAVHTFGELLSALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AMRRILGLQVW-PHRLASGFPDDVHIAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A351FH05_9BACT --dSLQSRVAARLDRLDAISSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA -SGRLDFGERYTVGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -DRVNALLQNEGFSQTRLKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA -EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYDGG-PSIVSVFTNQ -NTGDFFELEATLGLIAEDIVEAw ->[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI00130DA5E0 ---------VEKLEDLTGSISFLYENMITGDKV-SYRENEPMMAASVIKLFVMAAAFEKIE -KGVLDGSEMIGIRLEDCVPCGALTYLHEGIMVTVMDLITLMIIFSDNTAANVLIDLL-GM -DWINRFLKDQGFEKTLLQRKMYDLKLS-SQGIQNYITAGETGRLLKMMYEGILVSGQASQ -KMIGILKNQQL-CSKIPQALPEEPEIAHKTGEDR-GITHDVGIIYGK--EPFL-VCFCGN -KT-DTPAFERVMAQVSLELYE-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 12(A) TaxID=1163671 RepID=UPI0004634574 ------AEMVKRLEQFPGKVSFYFENLVTGETM-RYHEQAPMMAASVIKLFVMASVFEGLE -RELFQPDQMFEIKRAHCVPCGALTYLHDGIQVTLMDLVTLMIIFSDNTATNVLVDFI-GM -ESINGTISRLGFEKTVLQRKMFDLEKS-RQGIQNYITAGETGQLLNMIYHGNLVSRCASE -RMVSIMKNQQL-SGKIPFYLPDRPEIAHKTGEDT-GISHDVGIIYGK--VP-FIVCYCGN -ET-DTPCFERFMAEISLELYQ-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces yanglinensis TaxID=310779 RepID=A0A1H6C6Z9_9ACTN ---TVEQAIRDMFADAGVRGWLHASDLDRDARV-TIDPEHPAPMGSLYKVPLMAAFCRLVD -AGALDPRARVTLEPSDHVPPTGISLLRDPVSVSLRDLVVLMMTISDNTAGDAVLREV-GA -EAVEEVCRDLGMSRTHIEGGTARAWSVYDPLSKASGTPADLGRLLRAIWTDRAASAANCA -FMREIMGRQAW-RHRLASGFPDDVTVSGKTGTFG-AMRHEAGVVALPGGGTYVVAVFTRA -ARVDLPRADAVIGAAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Actinocorallia populi TaxID=2079200 RepID=UPI000D08CC71 ---------------------LHAVDLDSGREI-GVRPDESVVLASVFKVPLLVAFFRRAA -AGELDPVEQVALPPGARVAGGTGTSVLLDEIMSLRDLACMMITVSDNTAADTVLERV-GL -DHVNRTLTDLGLVRTRVTGSAGDLHAALDPAVSSRGTPRELTRLLAAIWRDEAAPAPECA -QMRRMLGLQIW-PHRLASGFPDDVLVSGKTGTLLT-LRNEIGVVEYPDGGRYALAVFTRA -RSATHPRADAAIGTAARLAVQ-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CS113 TaxID=1982761 RepID=A0A209BTV5_9ACTN ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGDLDLTEQVECLPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -EAVNRTSARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLAALWRDEACPAEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Salegentibacter salarius TaxID=435906 RepID=A0A2N0TXF7_9FLAO ---ELQQKLEALIDDFKGDVGIYVKNLETDKVV-AINADTIFPTASIVKVPILVKIFDNID -KGDLNYNDTLVYSTDRIYGGSGLMQFYQDSTTDLRTLVALMISYSDNVTSLWNQELAGGG -EAINELMAELGLEYTRVNSRTDGREKDWEKYGWGQTTPREMASILVEIRNRDLISPAASD -EMYRLLGNSFY-QDYALSQIPPYVQAAAKQGMVNK-SRSELFMVNAPSGD-YVCYLATKN -NEEDGNEAWELQRKISALLWNYf ->[subseq from] serine hydrolase n=1 Tax=Arsenicicoccus sp. oral taxon 190 TaxID=1658671 RepID=UPI00067C1A18 --qSLQRDLKDIVRHAPGRLSIQVVG-PTGVVA-GWDADREVPAASLVKVLVLVAALREVD -GGRLSLDQTLQLPE-ERVGGSGALSLLPSVTLAVVELLRLMVTLSDNDAANLLLHLL-GH -DRVTRTGREIGLQHTQVARNLRDRAAA-ESGRDNTTTAADQAGLLAALRAGQVLGGASTR -LALALLAEQQH-AYGVTALLPDGVVRGSKPGDLP-GVRHDVALVETGGS-WATVAVTATG -MY-DERH---------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2C5A8_STRVZ --------LRDAFAEAGVTGRLHAVDIDSGAEV-DFGADQPVVTASVHKLCLLVTLHQRAA -AGELDLTEQVECPADLRTPPTGISAMLDPVRMSLRDIAFLMMAVSDNTAADLLLARV-GL -DAVNATTAALGLDRTHAAHTFGELLAALDPARSNRSTPRDMTRLLAAVWRDEACAPEHGP -ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -AGAILPTADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PK15_9PSEU ----IGAEIEAVFADAGARGFVHAKQIGDGPEV-GVGADDQVVLASVFKIPVAVAFAREVA -AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIFHRV-GQ -AAVDQVLADLGLARTRLTGCCEDLFAVLDPDRTTSSTPREITALLDAIWTDRAGDTAACE -RVRKIMAQQIW-PHRMSSGFPAGVAIAAKTGTLP-AVRNEAGVVTDVDGRQYAVAVFTRA -DSDRLPAVDAAIGKAARLAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces variegatus TaxID=284040 RepID=A0A0M2GW32_9ACTN -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGILDLTEQVECPPQSRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLERV-GL -DAVNRSTARLGLGHTLAVHTFGELLAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinomadura echinospora TaxID=1992 RepID=A0A1H6A0H6_9ACTN ----IEERIERAFRDAGVVGCLAAIDLDDGRLV-GVRADRPVVIASVLKVPLLVALHRQAA -AGIVDLSEQVVLRPGERTTPTGVAVLQDEVRMSLRDLAAMMITVSDNAAADTLFARV-GV -ETVNAVLAELGLHRTHIPGCCRELFDALDPARTARSTPEEIAQLFAAIWRDEAAPAAECA -RMRRLFGLQVW-PHRLASGFPDDVQVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS -LSSVLPRADAVIGTTARMAVEH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004CD69F1 -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGILDLTEQVECPPQSRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLERV-GL -DAVNRSTARLGLGHTLAVHTFGELLAALDPARSNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. H23 TaxID=2541723 RepID=UPI00106E0AF6 ---ATAARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQAVCTASVHKACVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium IBVUCB2 TaxID=1985174 RepID=A0A1Y2RFN5_9BACT --kKLQSKLEEAIKGFNGDIGIYVKNLRTGKTA-FINADTIFPTASIVKVPILVGIMDKIN -SGELKYDSSLVYKDSLLYAGSDILGSFKNNEVLLKKVMMLMLTTSDNTASLWLQSLAGTG -TRINEILANHGFKDTRVNSRTPGREENRTQYGWGQTTPTEMGMLFEKIYHSEIISATACE -RMMRSLGRNYWDVDEAISMIPPTIEVFSKNGCVN-ASRSEVLLVNAPNN-PYIFCIFTKN -NKTHENEAWTMARKISKMLWDYf ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus metallilatus TaxID=1211322 RepID=A0A5R8UM16_9DEIO --------------GYVGEVGVLITDLAGRELY-ALHPARLFPAASTIKVPLLLLALGEAQ -AGRLDLRERVTVRAEDRVPGAGVLHELGPGLPTWEDLLTLMIVVSDNTATNLVIERL-GM -ERVNAWLGERGMIGTRLIGPLERQNEAQRRGERNRTSARDQVALLGALVRGEVLDQAHTA -LALSILGRQQL-RDLLGRHVPRGYRVASKSGELL-GIHHDVGVLFTP--RPLVAAVLSEG -G---------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=A0A4R6Q2G8_9FIRM ------EDIVKRLKEQKGRVGFYCKNLVTGQVM-EYKSDEQYLAASVIKLPVFMSISKWDS -EGKASMSDKVQVRNEDKEPICGALTLFTDEPVDVRTLCNLMISISDNTATNLLIKKY-GI -LELSNEFLKIGLKDTELNRILFDPDKS-HAGLENCIVPSEMAMLLEKVYRGTFVSKKVSK -DIEDTLLLQQI-NHKIGGIINDEVPIAHKTGEDD-GVTNDVGIVYA--REPFVICFA--G -TDTDVPEFEDLIRHVSYEVFKEy ->[subseq from] hypothetical protein n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=UPI001356587B ------------------------------------------------------------- --------------------------------GTVRSLSGAMISDSDNVATNLLVDRL-GF -ERINAAAQDLGLKETRLERHMLDFDAQ-AAGRENYTSARDTAALLAEIWHGRTLSPESRE -LALSTLELQTR-RAKIPAALPAGTRVANKTGELP-GVEHDAAIVLVPDRS-FVLVTLTSG -DPDS---GVEAIHAA-------- ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Microgenomates group bacterium GW2011_GWA2_37_6 TaxID=1618497 RepID=A0A0G0K3D1_9BACT --eQLKENVEKIIKNKKGFYSVYYKDLKTGELF-GIDENQIETGASVNKLPIITALYLLDK -KGKLSLDDKVTIQKEDVQDTGSIRYQKMPQVYSLRNLAKLALQQSDNTAAHVLSLRI-GE -ENVQKLVDSWGLKQTDMV--------------NNKTTVYDMSLLFEKIYRGEIANPANTK -ELLEFMTETEF-EDRLTKSLPSGTKIYHKTGDGE-GFVHDLGIIENGDQ-VYFLGVMTSD -IGDQEEQTKNTIAEISKKIFE-- ->[subseq from] Serine hydrolase n=2 Tax=Terrabacteria group TaxID=1783272 RepID=A0A2E0EAX4_9ACTN -----SKRWSDLAALQDLKVSAFMLALDDGRYA-ELNPDTALPAASAIKTPILLVALEEID -AGRLSWNEPLTLNKAVVGGGAGWMAKPLGTRFPTYEVATEMIRVSDNTATNLLIERVGGR -EDLNARFSSLGLSATIVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRSRD -LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIQLPDGHRAVAAFLVKG -PFND-PRSTELIRNMASAM---- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis lexingtonensis TaxID=218822 RepID=UPI00117741D0 ---KVEQRIADAFLAAGARGFVHAREIGGAGEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERVRVGKRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVIYHRV-GQ -AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAAEPAACE -RVRTIMAQQIW-PHRISSGFGSDVRIAAKTGTLP-AVRNEAGVLSFPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] Uncharacterized protein n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A3D1M3V0_9CHLR --kQLEENLKNKLASFEGVAGLSVKSLTGDEAL-SIKGNEVFPTASTIKIHILTKLFSMEE -EGQINLSKRVRFTESMYGSGSGVIHFLENVPFTILDVAILMMLVSDNTATNFCIDLA-GM -EDINDLIQDMGLVETKLRRKMMDPA-AINRGNENISTPNELVAIMQKLHDG-IPSKSVSK -QVLRIMSKPKS--AYINKAIGSDITIANKPGGMDK-VRGDTGIVYLSNN-PYAVSIMSNF -SMVDSISQENFIIDVIRTIH--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. CMAA 1363 TaxID=1843182 RepID=UPI000ADC01C6 -------------------NGLIRIHIEGKESI-RINSFIQQRAASTIKLLLAIEAFRQID -AGILALTSVIQRMEKNTVGGAGVLKALPQLTIKVEELLILMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLRKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A4P5V7M5_9CHLR ----------------NESVSIAAVHLLDGTGV-ALNADDVVPPASLFKLNILAETYRQIE -RNRVKLAQMITILPEDVAPGAGILQDRIGEAVSVGEALSLMIGISDNTAAFALLRTI-SS -RRLNECTRELGMLRTWFYVDER----------PDETSAGDVVTMLRAIIDGTIASPWGTD -QMLELMTQVQS-SAWIRSGLPPATRLAHKSGQLE-GIRNDAGIVFGPTG-PYALAVLTHD -LY-DPAVGEQIITAVTRVVHRYf ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. AG1013 TaxID=2183996 RepID=A0A370FI28_9NOCA -------------------------DRRAGIEV-GASPDQPVVMASVYKLPLLVTFCRLVD -AGDLDPRRQVTLDPSTRTTPTGVSQMSDPVRMSLRDMARSMMAVSDNAAADELLRRV-GV -DRVNETMGGLGLSSTRIVGGTADSLEGYDPVLSSATTPRDMTTLLSAVWTGAVLSADQTA -FVRVLMSSQVF-TARLRSGFPADVVVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPRADAAIGLAARAAI--- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1) TaxID=610130 RepID=D9R4S7_CLOSW -------EIIQKLEGLPGKISFLYENLKTGEGF-FYHEQEPMLAASVIKLFVMAAAFEKEK -KGTFRMNDIFAVKKEDWVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM -KEINETIKELGFRQTLLQRKMYDTERA-ARGIQNYITGYETGRLLKMMYDGTLIDKESSD -TMISILKNQQL-CSKIPQALPESPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERIMAEISLELY--- ->[subseq from] serine hydrolase n=1 Tax=Intestinimonas butyriciproducens TaxID=1297617 RepID=UPI0006910316 ---ELNAYLAAEIAAFPGKTSLLVADLPTGAVRhAWQPEEPVPSASTIKVPILLAALEEVR -LGRLSLEQRVALPAAALLPDTEVFDR-GETDCSLWELLYWMTALSDNTATNVILDLL-GL -DAVSRYATRLGLRHTVCRRKMLDAAAA-AAGRDNRTSATDQCRLYRQLCLGRLLTPRLTE -TALDLLRRQRCMDAALR-YLPYPVDFAHKTGELD-GVTHDAGVFFQGSGG-YYLGIFTWE -GPDGDPEQKRYIGRLARAIYETy ->[subseq from] Beta lactamase n=1 Tax=Streptomyces fulvissimus DSM 40593 TaxID=1303692 RepID=N0CJ25_9ACTN ------RTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTAFCRLAD -AGRIDPSHRLTLGAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP -EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPASCS -FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. LL01 TaxID=1665556 RepID=A0A0J5H1F2_9BACI ---ELKKRVQGVVDSTAGHVSFVLED-DGGRRL-EMDADAQKKAASLIKIPILMAAFKQVE -SGELKLTDRFSIEVEGRVGGAGVIQFMDSGTFTLRDLLTLMIVVSDNIATNKVLDII-GM -DAVGEFCAEQGLSRTRLERKMMDFEA-VDAGLENRTSARDMLACLKLLHFEGAFSDVSRQ -KMLSILGGQQL-LDKLPFYMDDSVKVANKTGELP-GVEHDCGIVSFGAK-KLMVAVLVDN -LF-DNSIGKRTIQEIGRLVEE-- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacillus brevis TaxID=1393 RepID=A0A517I1D1_BREBE ---ELEKRLSAIIGQAEGTWGVVVEEKGKGTCF-EHVPNELFIAESVIKVPIMAAVFAASE -QGHFRLDDPLVLRQEDLVGGSGILYALSPGLLTIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIDQTMIDLGMRKSCYSRKLMIYPLD--ITENNKITAGEVASMLGQMATGSYLSERACK -EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKD -VTA--QSALNTLGLLGRAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Kribbella catacumbae TaxID=460086 RepID=UPI0003631B78 -----SARIRATFDDAGARGWLHAVSLDHPDQTvALDPDVVVPIASVYKLPLLAAFCHLID -TQELNPREQVTLAPEDRIPGATGLSILQDPVMSLRDLAVSMMTVSDNAAADALLNRV-GV -DRLAQLLQSFGLEHTRVRRGAAGNLSMYDAAGMSASSARDMTTLLASLWSGRLLSEEQTA -FAQRLMQQQVF-SQRLASGFPDGVRVAGKTGTFG-ALRHEVGVVVMPGGDAYAVAVFAHA -ARGDLPRVDAAIGEAARLAVDQ- ->[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A3E4U320_9CLOT ----IERRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE -KGKASLEDMVEFKEEHAVDGSGVMCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA -KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK -FSDAAHPATVFGARVSRMLFDQf ->[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. Y74 TaxID=2478977 RepID=A0A3L7J7I5_9BACL -------QVKNALQHSSGKVSLAIET--KNGRI-DINSHKQMKSASTIKMAVLLEAFRQID -RDLVKPYDIIRLQPEDFTEGSGVLFHLGSVKLSFEDLLTLMIIVSDNTASNLIMRII-GI -GSVNALLNRLGCKETVLGRQFMDIQAAL-VGIDNFTSAADLVTMLKAVDSGELLSEDSRR -RVLHMLKKQQL-LANLHGRIDDEVSVASKSGSLP-GVVNDAGIFEYRGNK-VFAAVLVND -SP-DNHSGQELIAEIGGYIYD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia araoensis TaxID=228600 RepID=UPI0002EED88D ---------QEIFRTVGVEGWVHARCIDCGAEA-GIRADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRARAADRLGGVGTAGCADDVEFSLRDAAYFALTVSDNTAADLLFDRV-GL -DNVRSLLRELGLTATRVVGPPRTVVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR -WVRDLMRQQVN-WYRLAAAFPPEVQVWAKTGTLP-GVRNEIGVVEYPDGKRCAVAIFTRA -TTQRLPEVDRAIGAAA------- ->[subseq from] serine hydrolase n=1 Tax=Bacilliculturomica massiliensis TaxID=1917867 RepID=UPI0010300971 -------------SHMSGKTGFYYKDLATGETA-GFQEKAQFRAASVYKLPLFAGILLLAH -RGEADLFAKVRIAEDEKIPGCGAVQHLTGEPLDVLSLCKLMITISDNTATNALARYF-GI -ERMKPVFRELGLSGTQMNRCLYDLEKE-EQGIQNWIVPEELGGLLEGIHRRTLISPEVSA -YLEEILLQQQI-NHKIPGIMGENVPVAHKTGEED-GTTHDVGIVCAN--RPFVVCFTSNE -TD--VPVFEDFIR---------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID11233 TaxID=2706029 RepID=A0A6B3ERF7_9ACTN -------------------LHVAELHRPSARVV--IEPGEQLPLGSVYKVPLMAAFCRLAD -TGRIDPRHRVTLEPDDRVPPTGISVLHDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA -DAVDAVCRDLGMPDTRIHGGVVATFSVYDPAFKASGTPQDMARLLRAIWTDEAASAEGCA -FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q5QSE7_9BACT --kRLQKKIQELVSGFEGEVGIFVKCLRTGKTA-NVNADTIFPTASMIKIPILIGVMDKIQ -KGELNYQQTIIYRDSLLYPGEDLLGSVKQDEIVLGKIIMLMLTLSDNTASLWLQSLAGTG -THINELMDNLGLKNTRVNSRTPGRATNQSLYGWGQTTPREMCLLMEKIYKGEVINKHASS -MMLRLLGRNFY-DEYALSAIPPYIFVASKNGAVNQ-SRSETLLVMSPNG-PYIFSIITKN -QKDQS------------------ ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW105 TaxID=337067 RepID=UPI000E0F5A1E -------RWRQLAAQQDLKVSAFMLVLDDGRYA-ELNPDTALPAASSIKTPILLTTLELLD -SGNLRWNEPLTLTKQVVGGGAGWMATPLGTRFPTHEVATEMIRISDNTATNLLIERAGGK -EVVNTRFNALGLSATEVNNWLPDLQGT------NTSSARDLARAIALVDTGKALSTRSRD -LFREVMGTSVT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFMVQG -PFND-PRSTELIRSMAAAM---- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HZD5_9CHLR -------------DALRGRSGVLICEADETVRF-ARDPDGVCPAASVIKVPLVMALYAEAA -RGALDLEHCVEVGE--RVAGTGVLTHLRDVHLTLRDHAMLTIIVSDNTAANRLIDSV-GL -GVVNAYLDQWGCPRSRLRRKMFDLDAR-ARGLENVMTPRESAHLLGMLVRGELVDRAISD -AVLEILSATTY-DGNARRYLPGGVSTANKTGQLEN-VRNDVAIVRVD--RPVILAAFTRE -LA-SEADGEAALGVVGW------ ->[subseq from] Beta-lactamase class A n=1 Tax=Halorubrum aquaticum TaxID=387340 RepID=A0A1I2Z3G0_9EURY ---DLARAVDSIADRFDGRLGVFLGVPRGPDEFhRRNADETFVAASTIKLPILYALYETYD -GRLDDLGEPRPIAAENRVGGSGVLHLFDDPTPSLEDLARAMIAISDNAATNQLIDEL-GA -ERIEAAATRLGMADTRLRRKLMATLEQPEGEPANATTPMDCARFFADLVHEATLSAPAYE -RLRVPLDEQKD-ASLFARYLPYGTPIAHKTGGLPT-AALDAGVLDPPDASPLAFAAFATE -AE-NGGDASDVVAAVGEAAFE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 04229 TaxID=2203206 RepID=A0A429DNB9_9ACTN ---ATAARLGAAFAEAGVTGWLHAVDVDSGAQV-EAGADQAVCTASVHKVCVLVTLHEQAA -AGVLDLTEQVECPADGRTPGPTGLSAMLDPVLSLRDAAFWMMSVSDNTAADLLLHRV-GL -DAVNRTTERLGLTRTRAVYGFGEILGALDPARTNRSTPRDMTRLLTAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. SYP-B3965 TaxID=2663120 RepID=UPI0012998D33 --hKLEKALGELVKGFNGTAGVYVLNLKTGKYA-SLNGDTIFPTASIVKVPLLVGLFSKIE -KGELSFHQPMMYRDSIKYGGSGLMQFFKDSSTEVSVLAALMMAYSDNTTSLWNQQLAGGG -EQVNILMEQYGLKDTRVNSRTPGREEIRKIYGWGQTTPREMSFLLAKIHRGEVISKSASE -RMYRLMTKGYY-DEQALAEIPPYIQAAAKSGSVNE-SRSEVVLVNAPHGD-YVFYVGTKN -IKEADNEAVVMIRKISAYLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8N176_9ACTN ----------TLFSTAGVSGWLHAADIDSGREV-GHGADVPLPTASMFKVPLLVEFCRQAD -AGLLDPSDRVTVPAAGRSSPTGISAMLDEVTLSLRDLAYLMIAVSDNGSADVLLARV-GR -EAVNTMLAAQGLHGTRVLQSCQEFNDALDPERTNRSTSREMSALFGLIWRDEAASAESCA -WMRAALNKQVW-PHRLASGFPDDVAVSGKTGTAPT-LRTESGVVEYPDGRRYAVAVFTRS -FSLNQPRADAVIGTAARMAVDH- ->[subseq from] Uncharacterized protein n=2 Tax=Gordonia effusa TaxID=263908 RepID=H0R326_9ACTN ------DHVAHTFADAGCAGWVHARTLNSGVEY-GYRPDAPVVLASVYKLPLMISLCRMAD -RNDIDLAERVTVTPHDVAEATGLSVLHDPVTMSWRDLCVSMMTVSDNAAADVVLGRV-GL -HQLAADLADLSLSHTRIVSGMREVHAAYDAAYASAGTPRECTTLLDAVWRDVAASPDSCD -FIRRTMRKQVF-TTRIASGLAPHATVAGKTGTIGS-IRNEIAVVEFPGESSVAIAIFTKS -ARASLPTVDRAIGEVARAVV--- ->[subseq from] Serine hydrolase n=1 Tax=Rhodocytophaga sp. 172606-1 TaxID=2704465 RepID=A0A6C0GR65_9BACT --rQLQEKLNSIVKDFKGEVGIYVRHLKSGKTA-AIQADSLFPTASMIKIPIMIGLFNKIK -TGELDYHAKLVYRDSLLYPGEDILGSFKDSAISLSKIVMLMITTSDNTASLWCQYLAGTG -TAINTWLETNGFQHTRVNSRTPGRQANQQLYGWGQTTPREMGELLVRIREGKAVSPDASE -RMHRNLTRIYW-DGEALSQIPPSVQAASKQGAVNQ-SRSEVVLVNAPSGD-YVFCVITKN -QQDETNEGYVLLRNVSRLLWQYf ->[subseq from] Beta-lactamase enzyme family n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5L4J8_9BACT ------------------------------------------------------------- ------------------------------------------------------------- -------LKNIGDKTTKPARNEPELNLFNPKDNRDTSTPRQMVKNLQVYIFGDILSDDKKK -LLIDWMSDNSITDTLIKAETPQGWKVIDKSGSGDYGARNDIAVIYPPNRKPIVMAIMSRR -TEKNAKSDDAMIAEAAKRIFD-- ->[subseq from] Penicillin-binding protein n=1 Tax=Candidatus Beckwithbacteria bacterium GW2011_GWB1_47_15 TaxID=1618371 RepID=A0A0G1U4I8_9BACT ----------------NDRFGVWVEELSGSKSW-GLDETNQFTAASVIKLPILVAYYEAVD -EGRLDPETLYTLVEADRLEGTGSLQHQPAGTYSYREIAELTANQSDNMGAELLIKFLGGY -AAVQRTVNSWGLSETDLR--------------ENLTTPQEMGDLLTRLYRGELISEESRD -ELFANLTNTLV-EDRIPAGVPTGVKVVHKYGSEA-GVVNDCGIVYAD--TPYVICVLSQK -VN--AGEAEAVLPKISRVVWE-- ->[subseq from] Beta-lactamase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A174L172_9CLOT ----IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE -KGKASLEDMVEFKEEHAVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA -KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK -FSDAAHPATVFGARVSRMLFDQf ->[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A3E3DPJ4_9CLOT ----IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE -KGKASLEDMVEFKEEHAVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA -KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK -FSDAAHPATVFGARVSRMLFDQf ->[subseq from] Beta-lactamase n=2 Tax=Synechococcus sp. WH 8016 TaxID=166318 RepID=G4FIT1_9SYNE ---ALSKRWEALAAKDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVALEEID -AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERVGGQ -VDLNARFNSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD -LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG -PFN-DPRSTELIRNMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. LL01 TaxID=1665556 RepID=UPI00069DD080 ---ELKKRVQGVVDSTAGHVSFVLED-DGGRRL-EMDADAQKKAASLIKIPILMAAFKQVE -SGELKLTDRFSIEVEGRVGGAGVIQFMDSGTFTLRDLLTLMIVVSDNIATNKVLDII-GM -DAVGEFCAEQGLSRTRLERKMMDFEA-VDAGLENRTSARDMLACLKLLHFEGAFSDVSRQ -KMLSILGGQQL-LDKLPFYMDDSVKVANKTGELP-GVEHDCGIVSFGAK-KLMVAVLVDN -LF-DNSIGKRTIQEIGRLVEE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Leucobacter komagatae TaxID=55969 RepID=A0A542XXE3_9MICO --dTLTAQIAKVAEDAGVFAFAHARDIDTGREV-GFRSDDPTVTASVFKVPVLVEYVRQVA -AGELDPAQRIEVSPSEATMGPTGLSVFSDVAWSLRDIATSMITVSDNAATDIVTGLV-TV -DRVNSTMRELGLPGTQLTGDCSVIFDAATPEKTNRTTPREATSLLQQIWTDAAATPEACA -EARRILGMQVW-PHRLSAGFPDDVKISGKTGTIGM-VRNEIGVVEFPGGKRHAIAVFLRG -KTSRNPAADRAIGDIARLLSD-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus marisflavi TaxID=189381 RepID=A0A0M0GS42_9BACI ---------------------------SHDESL-SWEENRRKSSASLIKLPIMMTAFEQIQ -TGSLNGDAMVVLRHEDHVEGAGVLNGHDGITLSIEDLLKLMITVSDNTATNRLIELI-GK -DSINRFCLTWNLKRTFLNRKMMDFRS-LEMGQDNWTSSMDVVSCLKGINEGPF-KEASKR -KMLTMLSRQQF-RDKLPALVGGDVKVFNKTGELP-GVEHDCAILESTSGKIAYVAVLIDG -LQAP-EDGRRAISRIGKLVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33300 TaxID=525372 RepID=C2G3X8_9SPHI --qKLEKKLKELTRDFHGDIGIYVRHLKTNKEV-MINADSIFPTASIIKVPILAGVFNKIG -KGELKYNDKFIYRQSRAYGGSGLMQFFKDSVTDLSTMAALMIGYSDNVTSIWCQELA-EG -TKINELMDELGLPNTRVNSRTAGREAIWKKYGWGHTTPREMATLLTLIREGKVISPDLSD -KMYRILGNVFY-NERSLSQIPSYIKTASKSGSLED-VRTEVVLVNAPSGD-YVFSVFTKN -NKEKSNEAEVLTRSISSLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BEE1B2C -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREISEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. IEGM 248 TaxID=2704615 RepID=A0A6B2KC48_9NOCA --------------------------IDDGADI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL -ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPGVDAAIGHAARIAVT-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces azureus TaxID=146537 RepID=A0A0K8PX70_STRAJ -----LARIHAAFADAGVTGRLHAVDIDSGAQL-DAGADQPVCTASVHKLCLLVSLHEQAA -AGILDLTEQVESPPEGRTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADLLLARV-GL -EAVNRTTARLGLTRTYAVHTFGELLAALDPARTNHSTPRDMTRLLAAVWRDEACTPEHGA -AIRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSQPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Pedobacter sp. OK701 TaxID=2135718 RepID=A0A4R7ELC0_9SPHI --pKLEKALQQLVKGFNGDVGIYVKNLKTGKSA-GINADSIFPTASMVKVAITAGVFNQIE -KGQLDYKSVLTYKDSLLYAGEDILGSFINGEIALSKVLLLMITTSDNTASLWAQSLAGTG -TAINDLMSQYGLTYTRVNSRTPGRQENQKKYGWGQTTPKEMATLLTLIRNGKLINEAASE -RIYRNLIRIYF-DQEALSQIPPYIQAASKSGAVDE-ARSEVVLVNAPHGD-YVFCITTKN -QKDTSNEGWILIRKLSQMLWHYy ->[subseq from] serine hydrolase n=1 Tax=Arthrobacter sp. GMC3 TaxID=2058894 RepID=UPI000CE4A2C8 ----VRDALSATLTAVGVRGYVHAIDIDSGLEI-GLDADTPVVAASVFKVPVLVELCRQYS -TGQRSPVERVKIAANERRTGSTGISAMLDDILSLRDLSFLMMSVSDNRATDIIVDLL-GY -DAINATLGSFGLSDTVVTRDCAGLFVAATAELTNHTTPREITSLLAAIWRDEVIGAEAST -EVRRILAQQAW-PHRLTAGFPSNIKVSGKTGTLFY-TRNEAGVVEFPDGGRYAVGVFLRE -PTEENPDADRVIGTVAKLAIDY- ->[subseq from] Beta-lactamase n=2 Tax=Cyanobium sp. PCC 7001 TaxID=180281 RepID=B5INI0_9CYAN ------ESWARLAAAQGLQASGFLLVLDDGRYA-ELQADQALPAASSIKTPILLAGLEDVD -AGKIRWNEPLPLTKEVVGGGAGWMASRPGTRFPFFESATEMIRVSDNSATNLLIKRLGGK -EKLNARFQALGLPATVINNWLPDLEGT------NTTSARDLAKSIALVDTGETLSPRARD -LFREIMGTSRT-NTLIPLGLLQGVTVYNKTGDIGI-AYSDAALIHLPTGQRAVAAFMVKG -PFND-PRSAELIRSMAAET---- ->[subseq from] Beta-lactamase class A n=2 Tax=Rhizobiales bacterium GAS188 TaxID=1884351 RepID=A0A1H4S2V0_9RHIZ ----ASDIVAALRDRDGIDVGFSAIHLASGQCL-EINASSLFPTASVFKVPVMVEVFRQAR -AGIFAMSDRLTLATCHKTLTSGVLVTLDDGLPTIGDLVMLMTIVSDNTATKLLLDLV-GM -DKVNAAMAGYGLHDIHVAIDVHEMFLTFSRDRDNTASAADMARLMAMIAAGEVVDAEACG -SMVAIMKEQQY-SERVPRYLPFG-SVANKTGTMR-GVRNDSGIMRRGEGDDIAYAVFSFD -PTPLAAGNSRFLAE--------- ->[subseq from] Beta-lactamase n=1 Tax=Cupriavidus metallidurans TaxID=119219 RepID=A0A132HQX0_9BURK ---RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA -QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF -EGVNDWCDRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCRLLRDGSLPAPLRD -FALGLLADQRE-RAHFGAALPADAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG -FTDAGGDGAQWLAEAARIVA--- ->[subseq from] Uncharacterized protein n=1 Tax=Sphingobacterium spiritivorum ATCC 33861 TaxID=525373 RepID=D7VLX7_9SPHI --qKLEKKLKELTRDFHGDIGIYVRHLRTNKEV-MINADSIFPTASIIKVPILAGVFNKIG -KGELKYNDKFVYRQSRVYGGSGLMQFFKDSITDLSTMAALMIGYSDNVTSIWCQELA-EG -TKINELMDELGLPNTRVNSRTAGREAIWKKYGWGHTTPREMATLLTLIRAGKVISPDLSD -KMYRILGNVFY-NERSLSQIPSYIKTASKSGSLED-VRTEVVLVNAPSGD-YVFSVFTKN -NKEKSNEAEVLTRSISSLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Microtetraspora malaysiensis TaxID=161358 RepID=UPI000829A197 ---------KEVFDDADVEGFVHVREVDGSAEI-GLNPDEPVVLASVFKIPVVLEYARQAA -AGTLDRTERLTVTTADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -DNLHATLRGLGLGRTRLIGGCAELLGVLDPERTTSGTPRETTSLLSKIWRDEAGPAEACA -EVRKIMGNQVW-PHRLSSGFGDEVKVSGKTGTLP-GVRNEAGVVEFPDGRRYAAAVYLRT -DSFRLPQADAAIGRAARMAIEH- ->[subseq from] Uncharacterized protein n=1 Tax=Abiotrophia defectiva ATCC 49176 TaxID=592010 RepID=W1Q2D6_ABIDE --qAVQAAFASLYESKEIKHAYYFQEVTSQGAA-LVSQSGPIKSASIIKLFIMQVLLEEIK -AERLSWQEMITMMAEDQVGGTGNLQAEPGTSYSLEDLALEMLIHSDNTATNLIIERLGGL -SAVQAKIQSLGYQDTRLQRLMMDQV-AIAEGRENFTSAREVGQLLAKLYQHKLVGQAQDQ -IFLDFLAQQTD-RQGVVATLPQGVISYNKTGSNSQGLQHDAALVQLTNQSAYVLVVLQEG -PG--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. RSCCF101 TaxID=2511069 RepID=A0A5J6Q301_9SYNE ----------------DLKASGFLLILDDGRYA-QLAAGEPRSAASSIKTPILLAALEGID -AGSQRWDAPLTMDQEVIGGGAGWMAKPVGTRFPLHEAATEMIRVSDNTATNLVIRAAGGQ -EAVNRRFQDLGLTATVVNNWLPDLEGT------NTTSTRDLARTLALVDTGERLSPRARD -LFKEVMATSRT-NTLLPAGLLKGVSVYNKTGDIGI-AYADAGLIHLPDGRRAVAAFMVEG -PFND-PRSTDLIRAMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=A0A4R5ZWG5_9NOCA ----LKEKIREELYGFDGRIGLAIEI-EDAGNF-YIDSEEVFRSASLIKIPIFLAGLGRHK -IGELDVEQLIPISKENRVGGSGILYALSDQLLTVKDLMTLMIIVSDNTATNILIDLL-GM -DKINAFIREIGFEHTKLNRKMMDFA-AIEKGIDNFTNSREMIHSLKLLNENNVIGITGPP -IAYHALRHQQF-RDKLPAMVNEKITVVNKTGELPS-VEHDCAIFEYQGRKG-YVAVLTDS -V-IDQNEAKQIIRNIGKHISDFf ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. 209 TaxID=1955701 RepID=UPI00098D2F7A --sTLEKRLQTALTGFRGDVGVYVRNLRTGQTV-AINADTLFPTASTIKIPIQCGLFDKIH -QGELTYGQVLTYKDSLRYGDDIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG -ASINAWLDKNGFPQTRVNSRTPGRKGYWSQYGWGQTTPRELANLLVYIREGKAVSPDASD -EMYRNLGRQYW-DNDGLSQLPPEIKTAAKNGAVDR-SRSEVVLVHAPHGD-YVYCVMTKN -QKERSNEGFTLLRNVSAILWQYf ->[subseq from] Serine hydrolase n=1 Tax=Aminipila sp. JN-18 TaxID=2507160 RepID=A0A410PU96_9FIRM ---------------LKGHTGVYYKNLITGETL-LTKGEDQFLAASVIKIWVMAEAFYQIR -EGKIKREQKILLCDSDKIPEGGMPYLHSGIPFTVEDLYKLMIVISDNTATNMLIRLL-GI -DKINEFIASLHMSKTRLNRLLFDTSK----EKENTISLEEAGIFLEKIYRGEMISPEASR -EMCAILQNQQA-NFKIPFFLP-QIPIAHKTGEDN-GITNDVGIVYG--EVPFILCFAAND -A--DVPSANQACQEIARAAYRY- ->[subseq from] serine hydrolase n=1 Tax=Emticicia oligotrophica TaxID=312279 RepID=UPI00025F54D8 ---QLKAKLEETLKGFNGIAGVYVKNIKSNKFV-AINADTIFPTASMIKVPIMVGTFDKIK -KGELKYDQELTYKDSLDYDDGIVGSLKDGAKLPLNEVVMLMCTVSDNTGSLWLQALAGGG -KRINAIMDSLGLKNTRVNSRTPGREANRTEFGWGQTTPREMAELITMIRNGKVISADASD -RMYRNLGRQFWD-GEGLSQLPETVKYATKNGAVNR-SRSEVVYVHAPHGE-YVYCVITKK -QKDEENEGYELLRKVGALLWNYy ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium roseum TaxID=2001 RepID=UPI0004CCB976 ---------------ADVEGFIHVRDVDGGAEI-GLGADEPVVLASVFKIPIVLEYARQAA -AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -GNLHATLRGLGLERTRLIGGCAELLGVMDPERTTSGTPRETTTLLSKIWRDEAGPPEACA -EVRRIMGSQIW-PHRLSSGFGDEVKVSGKTGTLW-GIRNEAGVVEYPDGKRYAVAVFLRT -GSLRLPKADRVIGHAARVAIDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2ZJR2_9ACTN ----VSTRIRAVLRDAHADAALHARSIFGAGEV-GLDADRRSAAASTYKVAVLLEVACQTA -EGRIGAADRIRVPSDRRTTPTGISILNDDVEMSVRDLAMLMIHVSDNTATDVLHELV-GH -EAVTARLRALGLTDTSFELDCHHLIASLRGERGNTTTPRDMTSLLSAVWRDEAGPPEACS -EVRRVMGHQFA-PHRLSTAYPNGPSVSGKTGTLFGGIRSEVGVVDFGGGEAYAVAVYLRG -HRRRDPDADRAIGRVARLAID-- ->[subseq from] Serine hydrolase n=2 Tax=Pseudonocardia sp. CNS-004 TaxID=1904967 RepID=A0A1Q9SG80_9PSEU -----------------------------AREV-GVDPDEPVVMASVYKLPLLIAFCRLAD -AGDLDPREQVTVEPSARTTPTGLSIMRDPVTMSWRDLACSMIAVSDNAAADVLLRRV-GV -DRVNDALSDLGLARTRVHGGTADVYRAYDAVLASATTAREMTTLLAAVWSDRAASPQQSR -FVRELLGAQAW-QHRLRSGFPVGVRVAGKTGTLA-AVRNEVGVVQFDGERPVAVAVFTRA -ARAELPKADAVIGQAARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-4707 TaxID=1519496 RepID=UPI0006ADE094 ---SVAARLDAAFADAGVTGWLHAVDVDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNAAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. NRRL F-7442 TaxID=1519498 RepID=A0A0M8YU57_9ACTN ---SVAARLDAAFADAGVTGWLHAVDVDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNAAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00137519A5 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGYE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Siphonobacter aquaeclarae TaxID=563176 RepID=A0A1G9IBL9_9BACT ---RLQKEIDKLTTGFHGTIGVYVKDLKTGQTA-SVLADTVFPTASIVKVPILLGVMDKIE -KGQLGYHQNVVLTDSLRYPGSDEADMKTGEKIEISRLILLMLSTSDNTASLWLQGLAGGG -LRINAILDSLGYAQTRVNSRTPGRQHIRNRIGWGQTTPREMATLFEQIAAGKVFSRSASE -KMLRLLGRQYW-DQYALSQIPPDVFAADKHGCVNK-SRSEV--VYVAGDHPYVFAVFTQN -NQEPSNEAWTVTRKLSALLWKYy ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. ASBs410 TaxID=1304866 RepID=UPI000446AEB1 ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEAFETASTIKTYILACLFDEVE -KGNKSLEDMIEYKEEHVVDGSGVLPDLEPGALRVKDAATLMIIVSDNIATNMMIDYL-GL -ERINQCIKALGCKDTVLHNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE -KMLDILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. OF01-18 TaxID=2302962 RepID=A0A3A6KGA9_9FIRM --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLTLDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter pedocola TaxID=1792845 RepID=A0A1S9PBA2_9SPHI --rKLTAQLQEAVKGFNGQVGIYVHNLKTGKTA-AINQDTLFPTASMIKVSILSGLMDKIE -KGELRYNQKLGYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLVTG- -THINNWLDSNGFKSMRVNSRTPGREAFRSIYGWGVTTPYEMCKLFTMVRNGQVVSPAASE -RMARTLNRIYW-DNNALAQIPPYVQCLSKSGAVDE-SRSETVLVYAPHGD-YVFSVITKN -NKTPTNEASTLIRKVSALLWHYy ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. NAT40 TaxID=2024884 RepID=A0A2E0KBW8_9SYNE -------RWRQLAAQQDLKVSAFMLVLDDGRYA-ELNPDTALPAASSIKTPILLTTLELLD -SGSLRWNEPLTLTKQVVGGGAGWMATPLGTRFPTHEVATEMIRISDNTATNLLIERAGGK -EVVNTRFNALGLSATEVNNWLPDLQGT------NTSSARDLARAIALVDTGKALSTRSRD -LFREVMGTSVT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFMVQG -PFND-PRSTELIRSMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 7K507 TaxID=2530365 RepID=A0A4R4U7P7_9ACTN ---DVTQRIEAEFRAAGVTGFLHVTDIDTGREV-AVRAGDPVVLASVFKVPLLVTFHRQAA -DGLLDPAEPVTLRPRDRTAPTGISGMQDEVRMSLRDLTFLMITVSDNAAADVLLDRV-GR -DAVNATAAALGLRDTIVECGGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS -PLAVLPRADAVIGTAARMAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=A0A066TUG6_9PSEU ---TVEAAIAAVFAEADARGFLHAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA -AGRLDETARARVGSRYRIGGVGTAGCADDVEMSWRDLALFMLTMSDNAATDVIYHRI-GQ -AAVDRLLAGLGLGRTRLAGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGEAAACE -QVRSMMARQIW-PHRLSSGFPAEVAVAAKTGTLP-AVRNEAGVVTYPDGRRFAVAVFTRA -NSERQPAIDAAIGKAGRLAVDH- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Sphingobacterium spiritivorum TaxID=258 RepID=A0A380CPC3_9SPHI --qKLEKKIKELTRDFHGDIGIYVRHLKTNKEV-MINADSIFPTASIIKVPILAGLFSKIG -KGELKYNDKFIYRQSRAYGGSGLMQFFKDSVTDLSTMAALMIGYSDNVTSIWCQELA-EG -AKINELMDELGLPNTRVNSRTAGREAIWKKYGWGHTTPREMATLLTLIREGKVISPDLSD -KMYRILGNVFY-NERSLSQIPSYIKTASKSGSLED-VRTEVVLVNAPSGD-YVFSVFTKN -NKEKSNEAEVLTRSISSLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C105KSO15 TaxID=1776047 RepID=UPI000740888B -----------KLEQLPGKISFLYENLKTGDGF-AYHEQEPMMAASVIKLFIMAAAFEKSR -KGTFQMDELFAIKKEDCVPCGALTYLHDGILVTGMDLVTLMIIFSDNTATNVLIDIL-GM -EEINETIQGLGFERTVLQRKMYDTVRS-AQGIQNYITAYDTGRLLKIMYDGTLIDRQSSE -TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYGK--EPFL-VCFCGN -ET-DTPAFERVMAEIS------- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteriia bacterium AA117 TaxID=2169412 RepID=A0A321L8U5_9BACT ----LKQSLQRTSQSVSADWGIYVKSLDTGEEI-AINADAVMDTMSVIKVPLLVDAYRLVD -AGKINPADRITMATADKRFGTGVLRTLNDGLLSVHDAFMLMVIQSDNTATDMVYSRVGGP -QHVNQTMHQMGFSTINAPGTAFDWFSFEGKHPFGVSSGREMGRLLEMITSNKAASQKSCE -DMMRILRMQQM-RTRIPRFLA-EVSAPHKTGDFPPYIANDVGLIETEKS-RVVVVFFCAH -HRGVYAELEDAIGRMSEQVWAYf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Mucilaginibacter TaxID=2617802 RepID=A0A2J6H711_9SPHI ---KLTAQLQNLLKDFHGRAGVYVHNLKTGKTA-AINADTLFPTASMIKVSILNGVMDKIE -KGDLHYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG -EYINNWLATNGFKVMRVNSRVAGREDMRKIYGWGVTTPYEMCRLFTLIHEGKAVSPAASE -RMYRTLNRIYW-DENALSQIPPYVQAISKQGAVD-ASRSETVLVNAPHGD-YVFSIITKN -NQTPQNEADILIKKVSALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Algoriphagus vanfongensis TaxID=426371 RepID=UPI00047D8CB4 ---PLQEKIQPLLEQFHGKAGLYILNLKSGEEF-TYQADSIFSTASIVKIPIMLGIFDKIE -KGDLQFHQPLIYRDSIRYGGSGLMQHYQDSVTDLRTLLALMLSYSDNTTSLWNQSLAGGG -STINELLNTLGYQHTRVNSRTPGREKDWERFGWGQTTPREMASILTKIYRKELVSESASE -MMYRLLSNTFY-NDYAASQIPPGINVASKQGMVN-ASRSEVMLVNGHHGD-YVFALFTDE -NEDQQNEAWVLTRKLSSLVWNHf ->[subseq from] Beta-lactamase class A n=1 Tax=Prauserella muralis TaxID=588067 RepID=A0A2V4ANH7_9PSEU ----------DLFDAAGVHGWVHARCLGTGAET-GFGADEPVVLASVIKVPLVLEFARQVA -EGQLEPTDRVRVREVDRLGGTGTAGCADDVELSLRDVARFALTVSDNTAADLLFDRV-GV -DNVRSLLAELGLRATTVAGPPRDIVRALDPIRTTASTPMEMTRLLALIWSGEAAPPQACR -QVRALMAQQVS-WARLGAAFAPDATVAGKTGTLPC-VRNEIGVVDYPDGGRYAVAVFTRG -GGRPRPDIERAIGAAARHAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter curvatus TaxID=2094562 RepID=A0A2S7IIB4_9BACT --tRLQKQLETLVKDFHGDLGIYVEDLKTHSVV-AIRADTIFPTASIVKVPILLGIMDKIQ -RGQLDYHQSVTLTDSLRYKEADLVNAKTGEKIEISRLLLLMLSTSDNTASLWLQGLAGGG -LRINQLLDSLGYEVTRVNSRTPGREAIRNQYGWGQTTPREMARLFTAISERKIISPSTSE -KMLRLLGRQYW-DQYALSQIPPDVFVADKHGCVNQ-SRSEVFYVAGP--HPYVCAIFTKN -NQEASNEAWTLTRKISVLLWKYy ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) TaxID=562970 RepID=D5WWQ1_KYRT2 --tALKQAISGYVTSQPGAYGVVVVDLDSGAKL-DIDGNRVFFAASTFKLPMNLYLYTLIA -QGKVDPNTKLIYEASDYEDGTGIASTPVGTEYTIRQLSQASIVASDNVATNILLDDL-GV -DNVKAFMRQLGGKQV--------------VDGDNVTTPDDMALYAVKLFEFAKKHPTVAA -PLIDDLEHTDF-NDRIPAKLPANVPVAHKIGNWTD-QWHDVGIVFLPGR-PYVISLFSRD -IDQD--TAAQVLSTVSRMVYDY- ->[subseq from] serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=UPI00067907D3 --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVSVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-146 TaxID=1463884 RepID=UPI0004C745EE -----LARIHAAFADAGVTGRLHALDIDSGAQL-DAGADQPVCTASVHKLCLLVTLHEQAA -AGLLDLTEQVECSPQARTTPTGLAAMLDGARLSLRDLAYLMMSVSDNAAADQLLERV-GL -DAVNRTTARLGLARTLAVHTFGELLAALDPARTNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRILGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ARTSLPAADAVIGTAARLAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Myxococcales bacterium TaxID=2026763 RepID=A0A2D8JEG7_9DELT --dSLQSRIAARLDGLDAISSIYAKHIPTGREI-AVRADLPMNTLSVIKIPVMIQAFQDNA -SGRLDLGERYTVGPNDMRRGSGLIQTFEHGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -DRVNALLQEEGFSQTRLKATTGDLFRTFEGDSTGRTTAREMGSLLEQILNAELADEEASA -EMISILTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ -NTGDFFDLEATLGLIAEDIVEAw ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D2UDV6_9BACT --dSLQSRIAARLDGLDAISSIYAKHIPTGREI-AVRADLPMNTLSVIKIPVMIQAFQDNA -SGRLDLGERYTVGPNDMRRGSGLIQTFEHGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -DRVNALLQEEGFSQTRLKATTGDLFRTFEGDSTGRTTAREMGSLLEQILNAELADEEASA -EMISILTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ -NTGDFFDLEATLGLIAEDIVEAw ->[subseq from] Beta-lactamase class A n=1 Tax=Thermostaphylospora chromogena TaxID=35622 RepID=A0A1H0ZY77_9ACTN ----IEERIREVFARVGVTARFHVIDVATGDEV-GLNADEQEVLASLFKVLPLLEFARQVA -AGQLDPTERVVVRSADRLGGWGTAGCADDVELSLRDLAYFMMSVSDNTAADLLVRRV-GL -DTVRMLVAELGLARTRIIGGSREMLAALDPEHTTSSTPREMTRLMGMIWRDEAGHPAACA -MVRELMTRQIF-WTRLGSGFPPSVRVASKTGTLP-GLHIEAGVAEYPDGGRYAIAVFARS -HNLQRIDIDLAMGRAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000C9B94C3 -------------------NGLIRIHIEGKESI-QINSFIQQRAPSTIKLLLAIEAFRQID -AGILALTSVIQRTEKHTVGGAGVLRALPRLTIKVEELLTLMIVVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRK -KIMRMLKIQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3B8VCT6_9BACT --------FADIESKYEGNLHIHAIKLGSETSW-KYRENDLVATASTIKLPILMHAAMCVY -DGYLSWDTKITLKESDKVGGMGVLQHLNTPHLTLHDACYLMTAISDNTATNLVMDVV-GI -DNVNQFIRTFGLTDTKLFRKAFSPNTESKVFGLGQTSASDMLTLLSEIYRPNKLPLSVVN -DIRSMLSKQTD-QVSIPRVLPHGWSYEGKTGRVTE-VRGDVGYVKAPDGREWLLSMFCYG -LTTE------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Sediminibacterium goheungense TaxID=1086393 RepID=A0A4R6IWQ4_9BACT --kKLQQKISRLIQGFNGDIGVYVHDLKKNKIA-VINADSIFPTASMVKVPILVGIMDKIG -KKELDYHQTLTYKDSLLYEGVDILGSFKNNEIELSKVIMLMLNTSDNTASLWLQSLAGTG -TRINQIMDSLGFKDTRVNSRTPGREANRTQYGWGQTTPREMAALFERIAGKQLLNDSASE -KMLKLLGRNYW-DEEGLSAIPAGIFVASKNGAVN-ASRSEVIYVNG-GGARYVFCICTKN -NKDQ------------------- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K309 TaxID=2530384 RepID=A0A4R4VKE0_9PSEU ----AEQRIRDVLADAGAQGWVHAVRLGGGHEL-GFGADELVVTASVYKLPLLVALARAFD -AGTLDPREAIRLDPGSCTPPTGVSTFQDPVRMSWRDLAASMIAVSDNAAADVILGAI-GL -DSLAAALDDLGLERTRVVGGTADAHAAYDPSYASATTPREMTRLMELIWADEVASPQQCA -FVRRLLGQQAW-MHRVRAGFPQGVQVSGKTGTIG-AVRNEVSVVEFDGEAPVAVAVFTLA -ARADLPRVDAAIAECARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga jiangningensis TaxID=1419482 RepID=A0A1M7L0S6_9BACT --kKLQETLTHLLKDFHGQVGIYVHHLKNDKVV-EINADTIFPTASMIKTTIQVGIFDKIA -KGELQYRQPLIYRDSLLYAGVDILGSFKDSQIDLDKVVMLMLTMSDNTASLWLQSLAGGG -ATINSWLEQHGFKVLRVNSRTPGREEIRKVYGWGQTSPREMAQLMEMVYKGEVIDKASSE -RMYRNLTCNHW-DAQGLLQVPANIRTASKNGAVDD-ARSEVIMVNGPHGD-YVYCITTKN -IAKPENEAWRLMRKVGSAIWQHy ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF258FC -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALLRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREISEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. ZY74 TaxID=2488634 RepID=A0A3N4PXG4_9BACT --rKLQQALEEIVGRFNGRAGIYVQHLKTGAWA-AVNADTVFPTASIVKVPLLVGLFAKID -SGKLGYHQPMIYRDSAKYGGSGLMQFFKDSATEVSVLAALMMAYSDNTTSLWNQQLAGGG -AEINRLLEQYGFKDTRVNSRTAGREEIRKIYGWGQTTPREMTTLLIRIRRGEIISRAASE -RMYRLMSKGYY-DEQALTQIPPYVQAAAKTGSVNE-SRSEVVLVNAPHGD-YAFYIGTKN -IKEADNEAVEMIRTVSALLWKHf ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga niastensis TaxID=536980 RepID=A0A2P8HIN9_9BACT ---RLTAILTPMLASHHGQAGIYVHNLKTGSTV-AINADSTFPTASMIKTAIQVGIFNKLS -KGELQYHQNLVYRDSLLYEGEDILGSFKDSQIALDKVVMLMLTMSDNTASLWLQSLAGGG -VQINQWLQDNGFEHLRVNSRTKGREAERKQYGWGQTSPREMARLMEMVYKGEVISKTASE -RMYRNLTRNYW-DAEGVLRVPPNIRTASKTGAVDE-SRSEVIMVNAPHGD-YVYCMITKN -NQDQDNEAWQLLRRVGDVIWQYy ->[subseq from] serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=UPI000A50084D --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDKVR -RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. KC06 TaxID=2530369 RepID=A0A4R4XVX1_9ACTN ------ERIEKEFRSAGVTGFLHAVDIDTGREV-AVRADAPVVLASVFKVPLLVAFHRQAG -EGLIDPSEQVTLPAEGRTTPTGVSGMLDEARLSLRDLAFLMITVSDNAAADVVLERV-GR -DAVNAASAALGLRGTAVEVSGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPAGCA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -PLAVLPQADAVIGTAARLAVEH- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Pseudomonas sp. TaxID=306 RepID=A0A348SI35_PSESP ------ARLAQVDRQTPGQLGVYVKDMQTGISV-SYHGEDAWYLASTVKVPIAIAVMRRVE -QDDLTLDSPVTLLASDYVDGAGPTNRHAPGKLSVRYLLDQMLIHSDNTASDMLIRLV-GI -DQVNAVTRELVPEGFGPITTLADVRRRYYATPFNSGTLKAYGDLLSALDAGTALGPASTE -YLLSVMRRVETGGRRIKAGLPSGT------------------------------------ ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A4P5T6U7_9BACT --kKLEQKIKTLIQGFNGQIGVYVKNLKSDKIV-SYNGDTVFPTASIVKVPILIGIMDRIH -KKELDYHQKLVWYDTMNYDGEDIVAYKPQSEIELSKVMMLMMTISDNTGSLWLQSIAGTG -KRINHLLDSMGYHATRVNSRTPGREGDRSIFGWGQSTPNEMGRLMEDIVHGKIISKDKSD -QMLRIMGRQYW-DEEALSAIPPTVFVASKNGAVNA-SRSE--ILYVNGRRPYIFSVFTKN -NKGNENEAWQLTRKLSKLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. Root239 TaxID=1736499 RepID=A0A0Q9ICX9_9BACI -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILTLTSVIQRMEKNTVGGAGVLRTLPRLTIKVEELLTLMIIVSDNTATNELISLV-GF -EKINECAKDLGLKKTVLNRYMMDEI-AVGKGIDNYTCASDVVKCLREIYEGNFLRKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A133N6E3_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -NKINETIKELGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Beta-lactamase n=1 Tax=Synechococcus sp. (strain WH8020) TaxID=32052 RepID=A0A0H4B6M0_SYNPY ---ALSKRWEALAAQDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVAIEEID -AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTYEVATEMIRVSDNTATNLLIERVGGQ -ADLNARFNSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD -LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG -PFN-DPRSTELIRNMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=UPI0006D7F522 --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERSAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229R8G9_9PSEU ---AISDEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYHRI-GQ -DAVDKVLTDLGLTRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAGVGIAAKTGTLP-AVRNEAGVVTQVDGRRYAVAVFTRA -DSDRLPAVDSAIGEAARLAVEH- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma aerolatum TaxID=1211326 RepID=UPI0009ABB975 ---RLEQKLQSALAGFRGNAGVYVYHVRTGKRV-SINADTLFPTASMIKIPIQCGLFDKIH -KGELSYNQELVYKDSLHYDDGIVGSLKDGARITLSKVVMLMETISDNTGSLWCQALAGGG -TAINTWLETNGFHQTRVNSRTPGREANRSQYGWGQTTPRDMANLLLYLRQGNAVSPDASD -EMYRNLGRQFWDGDGL-SQLPPDVKVASKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN -QQERTNEGYALLRTVGSIVWHHf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Subdoligranulum TaxID=2685293 RepID=A0A372V960_9FIRM --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter psychrotolerans TaxID=1524096 RepID=A0A4Y8S7P0_9SPHI --kKLTAQLQTAVQGFKGQVGIYVQNLKTGKTV-AINQDTLFPTASMIKVSILSGLMDKLE -KGELKYNQKLAYRDSLLYAGEDILGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLVTG- -THINNWLDSNGFKSMRVNSRTPGREAFRKVYGWGVTTPYEMCRLFTMIRNGQVVSPAASE -RMSRTLNRIYW-DNTALSQVPPYVQCLSKQGAVDD-SRSETVLVHAPHGD-YVFSVITKN -NKTPNNEADVLIRKVSALLWHYy ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. Leaf194 TaxID=1736297 RepID=A0A0Q5U4R3_9SPHI --qKLQLKLNELVKGFKGDVGIYVKNLKTGKTA-SINADTIFPTASMIKVPITCGVFNKIE -KGELDYHAQLMYCDSLLYAGEDILGSFKDSEISLSKVLMLMITTSDNTASLWAQLLAGTG -TAINEVMANNGLKDTRVNSRTPGRKDNQKKYGWGQTTPKEMATLLALIRDGKMINPAASE -RIYRNLIRIYW-DSEALSQIPPTVQVASKSGAVD-AARSEVCLVNAPHGD-YVFCINTKN -QQNYSNEGWTMIRKLSNLLWNHy ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=UPI000AFB9D8D ---SAQQEIAAVLAEAKTDAYVHARDIDSGEEF-GYGADEGVILASVFKIPVVLQYAREVA -AGTLDPTEHATVTAEFRSGGIGIGGCADDVTASWRDLALLMMSFSDNAATDFLYERL-GL -DNIVATLRGLGLEKTNLVRDCRGLFKVMDPARSNSSTPREITMLLAAIWRDEAGPASACE -EVRTIMSKQVW-PHRLSSGFPDEVTVAAKTGTLGL-VRNEAGVVAYPDGKRYAVGVFTKS -HELT------------------- ->[subseq from] serine hydrolase n=1 Tax=Intestinimonas timonensis TaxID=1689270 RepID=UPI001031497C --qALDTFLKQEIAAFPCKTAVLVGEVESGKVLwALEPDTQVVSASTIKVPVLLAALEEVR -QGRLSLDQTLDLPAEVLLEDSQVFEYG-PTSRSLWELLYWMIVESDNTATNRVISTV-GY -DAINAYARDLGLRHTVCQRQMLDWD-AIAAGRNNYTSAADQFALYRKLCRGEILNESLTA -VALDMLRRQRSMDDIL-RYNPYPVDFAHKTGGLDY-LSHDAGVFFQPGGD-WFLGIFTWD -GPEGDNRQKQFIGRLGKAIYDTy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces olivaceus TaxID=47716 RepID=A0A1D8SRN5_STROV ---ATAARLDAAFADAGVTGWLHAVDIDSGAQT-GTGADQPVCTASVHKVCVLVTLHELAA -AGSLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GR -DAVNRTTARLGLTRTRMAYGFGEMLAALDPARTNRGTPRDMTRLLGALWRDETCPAEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 6K520 TaxID=2530364 RepID=A0A4R5EF83_9ACTN ----VTGRIEAEFRAAGVTGWLHVVDMDSGREV-AVRADAPVVLASVFKVPLLVAFHRQAA -AGVLDPAEPVTLDPGDRTAPTGISGMLDEVRMSLRDLTFLMITVSDNAAADAVLDRV-GR -DAVNAAAAALGLRDTVVEVSGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS -LLAVLPRADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Actinocatenispora sera TaxID=390989 RepID=UPI00068EF62F ------DEIRSVFTAAGATGFVHAREIGDGPSV-AVAADEPVVLASVFKIVVAVAYAREVA -AGRLDPRERATVTVGYRIGGIGTAGCGDDVQMSWRDLARNMLTMSDNAATDVVFHRV-GQ -AAVDAVLADLGLTHTRLCGCCTDLFAVLDPTRTTASTPAEITALLDAIWTDRAASPEACA -QVRAIMAEQIW-PHRLSSGFPDGVGIAAKTGTLP-AIRNEAGVVSYPDGRAYAVAVFTRA -SSQRQPAIDAAIGTAGRLAVEH- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E9UDW4_9CHLR ---KLVNSINNQVENFKGVAGVSIKDLTTGWYY-GINDELIFPTASSIKIPILLKLIESSE -TSKLDMLKNIEITEEMKSRGSGVIHKMNGTILTVENLAILMINLSDNTATNLCIDIA-GQ -DEVNKMLEDYEFVSMRLNRKMQDYT-AIKEGRENLSSVKEMNLILEMLDSAQAIKPEVAK -KVLNILSLNKS--TPISQPLPENIIVAGKTGGMP-GVRCETAIIYLANRK-YILTVMTSH -AGNGSSSSKQ------------- ->[subseq from] Serine hydrolase n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=A0A3B9WE55_9FIRM --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVSVTAEDILPDTGVFLDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Gordonia insulae TaxID=2420509 RepID=A0A3G8JPT2_9ACTN -hdRLTREVTAILADAGCAGWVHAESLGRPDHAfGAGADAPVVLASVYKLPLMISLCRMSD -RGELDMSEQVEVAPDEWSSATGLALLHDPVRMSWRDLATSMMTVSDNVAADVILTRV-GL -DTVLADLADLRLAHTRIVGGMRELHAAYDAAYSSASTPRDCTSLLAALWRDDVAVPETCD -FIRATMRAQVL-RSRLASGFPRHVAVAGKTGTLA-AIRNEIGVVEFPGEHPVAIAVFTKS -ARPSLPEVDRAIGRVARAVVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E0B742_9CHLR ---NLENTLVSKINEFEGVAGLSIRSLKNKNTI-SINGDEIFPTASSIKIHILTQLFSLEE -KGMIDLSKRIQFTQDMYGAGSGVIHFLENDPFSILDIAILMMLVSDNTATNMCIDLA-GM -KETNNLIKSFGLSKTKLGRKMMDAX-AINRGXENISTPNELTTMMELLYQKKP-SAKVSE -NVLXIMSKPKS--AYLNKAVGPNXKVANKPGGMDK-VXCXVGIVFLPNN-PYSISXMTNY -GXXDSLXQEAFIXXIAKTV---- ->[subseq from] Uncharacterized protein n=1 Tax=Microbacterium sp. Root61 TaxID=1736570 RepID=A0A0T2KX19_9MICO ------DALLAAFAEVPVRGLIHAVDIDTGHEI-GVGSDESVVSASVFKVPVLVELCRQYS -SGRIDPRARIALGADERRTGSTGISVMLDELLSVRDMSLLMMSVSDNRATDVITDLV-GL -DNVNATMREFGFDRTVVDYDCDMLFAATTPEETDRTTPRQIAELLSAIWRDELLDADAAA -EVRRVMGLQAW-GHRLTAGFSPAVRVSGKTGTLFY-VRNEVGVVEFPTGERFAVAVFLQE -PTPRNPDADRVIGTAARLAVDY- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=A0A4Q9HTU5_STRKA -----LTRIREAFDGAGVTGRLHALDIDSGAEV-GASADHPVVTASVHKLCLLVALHQQAG -AGRVDLTEQIECPPAGRTPGPTGLAAMLDPVMSLRDAAYLMMAVSDNTAADLLLERV-GL -DAVNHTTARLGLAHTHAVYTFGETFGALDPVRANHSTPRDMTRLLAAIWRDEACAPAHAA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -TNATFPPADAVIGTTARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF65317 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLMIIVSDNTATNEFISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A374NXG9_9CLOT ----IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGADEPFETASTIKTYILACLFDQVE -KGKASLEDMVEFKEEHAVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLGCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA -KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK -FSDAAHPATVFGARVSRMLFDQf ->[subseq from] hypothetical protein n=1 Tax=Acidisphaera sp. L21 TaxID=1641851 RepID=UPI00131B60AC ----VQSRIEAVLSPLGIEVGFAATHLQSGANV-AINPGILWPTASVFKVPVMVEVYRQAE -AGRFGLSDRMPMPDEQRTVGSGVMQKLAPGLPTIRDLVMLMTIISDNTATEMLLDLV-GA -EQVTATMHRLGLHDIHVVLNLPQLFAAFAMTAENTASAADMAKLMALIVQHEAGSAAACT -DMLAVLGAQQL-RDRVPRYLPARA-TANKTGTFK-GIRNDAGLMLRGPDDTIAFALFTFD -RT--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Ruthenibacterium lactatiformans TaxID=1550024 RepID=A0A0W7TVC0_9FIRM --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVAVTAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. 150FB TaxID=1576605 RepID=A0A0C2BBP7_9ACTN ------------------------------QEV-CVGADIPVVVASVYKLVALVAFCRAVD -AGELDPRQQVTVEPHRRTPPTGISALSDPVTMTWRDLATSMITVSDNAAADAVLERI-GQ -DRVRAVIEDLRLPGTRIHGGTAEAQRELDPTFGSATTPRDMTRLLTVLWRGEAASPEQTR -FARRLLEAQVW-PHRLRAGFPGAATVAGKTGTVG-AIRNEVGVITYPGEHPVAVAVFTHA -ARTDVPRADAAIGAAARHAVN-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium 13_1_40CM_65_14 TaxID=1803459 RepID=A0A1Q7GSQ9_9BACT -----ASRAGEIAAGLDGALGVSVFDYLSGFAW-GLDGDRWFHAASTIKVAILAGLFDAIE -RGRFTLDSRLHVRNRFLSVGQPFRHASIGKTMRVGELARHMIVRSSNLAANLLLDLV-GV -EETRAALAARDITGVDVCRGVED-ERAFEAGLSNRVTADGIVGLLRAIRDGRGFSPESSK -AMIDILMDQEF-AGGIAPGLPAVARVAHKTGDIST-VSHDAGLVFLPGRPPYVVAILAAC -AG-DPSARNEALAAISGLVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Cyanobium sp. NIES-981 TaxID=1851505 RepID=A0A182ANF9_9CYAN ----LSQTWARLAAQKGLQASGFLLVLDDGRYA-ELQADQALPAASSIKTPILLASLEDVD -AGKIRWNEPLPLTKEVVGGGAGWMAKPVGTRFPFFESATEMIRVSDNSATNLLIKRLGGK -DKLNARFQALGLPATVINNWLPDLDGT------NTTSARDLAKAIALVDTGEKLSPRARD -LFREIMGTSRT-NTLIPLGLLQGITVYNKTGDIGI-AYADAALIHLPNGQRAVAAFMVKG -PFND-PRSADLIRSMAA------ ->[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces lividans TK24 TaxID=457428 RepID=D6ENE9_STRLI -----AARLDAAFADAGVTGWLHAVDIDSEAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Carboxylesterase, beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain CC9311) TaxID=64471 RepID=Q0IBJ5_SYNS3 ---ALSKRWQALAAKDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVAIEEID -AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTYEVATEMIRVSDNTATNLLIERVGGQ -ADLNARFNSLGLSATKVNNWLPDLKGT------NTTSARDLARAIALVDTGEVLSIRGRD -LFREVMGTSVT-NRLLPGGLLKGYRVFNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG -PFN-DPRSTELIRNMAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Sinosporangium album TaxID=504805 RepID=A0A1G7X7F8_9ACTN ---SVEQEIRDIFTEADAEGFVHVREVDGDGEV-GVLPDAPVVLASVFKIPILLEYARQVA -KGTLEATERLTVTAEYRDGGIGTAGCLDDVSLTVRDLAHFMITQSDNAATDVLLRRV-GL -DNVHATLRGLGLDRTRLIGGCQELMAVRDPEQTTSSTSRETTSLLAAIWREEAGPAEACA -EVRRIMYNQVW-PHRLSSAFGDEVRIGAKTGTIM-GIRNEAGVLEFPDGARYAAAVFLRP -RGVRLPKADAAIGEAAKAAIDH- ->[subseq from] SH3b domain-containing protein n=1 Tax=Cyanobacteria bacterium UBA8530 TaxID=2055790 RepID=A0A355UTW5_9CYAN ------ARLAEIAD-RGGRVSIAFHHLDSGEKW-AWRGEKTFPAASLIKLPLMAACYRLAG -AGKIFLNERVLLSEAVGDGKEPFDDAPLGEYFTLRKLIDRMITESDNTATNTLLERI-GF -EPVRELLDAWGLKETKLERKMLDWESR-RVGRENTTTAEDMLSFLLQLQRGDDFPSAWKE -EMWGLLTHQRD-KTKMARRLP-HLDLAHKTGEIPN-IRHDVGRIKATNS--FLLAVLTEN -LE----KANTVIGRLSEAIVRHy ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharomonospora cyanea NA-134 TaxID=882082 RepID=H5XFB7_9PSEU -------------EATGVHAQVHARCLATGRQT-GVGSGERAVLASVVKVPLVLEFARQVA -AGQLDPADRVRVSAEDRLGGTGTAGCADDVELSLRDAAFLAMSVSDNSAADLLFDRV-GV -DNVQALVTELGLTATRVVCPPRDVVRALDPAHTNAGTPEEMTRLLELVWTDRAGPPESCA -AVRRWMAQQVN-WLRLGSAFPAEASVAGKTGTLPC-VRNEIGVVTYPDGGRYAVAVFTRV -ASGRRPDIERAIGLTARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces triticagri TaxID=2293568 RepID=A0A372M6J2_9ACTN ----ATRTIRELFADAGVRGWLHVAELHREARV-TIDPDEPVPMGSVYKVPLMVAFWRLVD -AGTLDPRSSLTLEPAHRIAPTGISILQDPVTMSLRDLVVLMMTVSDNSAADAVLRTV-GA -PKVDEVCRELGLPDTHVLGGVANTWAVYNPASKSSTTPADMARLLREIWTGRAASAEHCA -LMREVMGRQAW-RHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSTYTAVVFTRA -ARADLPRADAVIGAAARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. A1547 TaxID=2563105 RepID=UPI00144A4EBC -----LHRLRAAFAEAGVTGRLHAVDIDSGTEI-DAGADQPVVTASVHKLCLLVALHEHAA -AGRVDLGEQVECPPGDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DGVNEATARLGLTRTRAVHTFRSLFAALDPAHSNRSTPRDMTRLLAAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTTARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW179B TaxID=2575516 RepID=UPI000E0E26ED ---ALSKRWEALAAQDDLQVSAFMLALDDGRYA-QLNPDTALPAASAIKTPILLVALEEID -AGRLSWNEPLTLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERVGGQ -VDLNARFNSLGLSATKVNDWLPDLKGT------NTTSARDLARAIALVDTGEALSIRGRD -LFREVMGTSVT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGRRAVAAFVVKG -PFN-DPRSTELIRNMAAAM---- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GCJ3_9BACT --------------------------LETGFRF-SFRGDRWFHAASTIKVAVLLAVFRAAD -EGQFRLDDSLHVRNRFFSAADGSLYAAIGRTAKISSLAYAMICGSSNLATNLLLEFV-GV -EYARKVLGGAQVDGVELRRSVEDH-GAHEQGINNEATADGLLRLLS-VIRGDFLTPESKR -EVIRILLEQRF-NSMIPAGLPPHATVAHKTGETST-ACHDIGIIYLPEREPYIAAILTEF -DP-EREGRRETVAAISQAIYR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8NHG2_9BACT ---SLDAQVRAETAQFKGKVSLFARNLDSGESY-SLNGDERVPTASTIKIAVMIETFARVA -EGRAKWTDELVLTKAARYGGSGVLPELSDGLLTLRDCVNLMMLVSDNTATNMVLDYL-TT -DAVNARMDSLGFKQTRIMRRVGGGGESKDGKVADATTPHEMVQILDKLDRGEVISPAASK -EMLDLMKREQA-RYAIGRTIW-SVPMASKYGALDH-LRSCLAIVYSKRGR-TAIAITVDE ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Salegentibacter sediminis TaxID=1930251 RepID=UPI0009C157C1 --tQLQQKLERYTKDFRGTAGVYVFNTKTGKQA-GVNADTIFPTASIVKIPILVGLFDKIN -EGELNLNDSLIYRDSRQYGGSGLMQFYKDSTTDLRTLAALMITYSDNVTSIWSRELAGGG -ESINPLMEKLGMKHTRVNSKTRGREKNWEKYGWGQTTPREMATLLVKIRNREVVSNAASD -EMYRMLSNSFY-TDYALSQIPPYIQTAAKQGMVNK-SRSEIVLVNAPFGD-YVFYIATKN -NLDTGNEAWELQRNISAMLWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1M6R1L0_SELRU ---DLQANTARIIGDSVNQMSVYFLRPDREMEP-FLYNQRQLSPASIIKLFVMAKTMQDVH -DGKLNLTDKITIRKKDVVGGAGVLTWYDAGQRTVLQLLTVMITDSDNTATNLLIDRLGGM -KSINQYLAQYGYTDTVLAHKMMIGN----GGRKNLSSVRDLGHLLTRLYYHQLVGPEEDE -IMLDILKQQHD-KECLGSALP-EYVIAHKTGEVT-GVYADGGVFFGQNED-FILVILNNG -TEGRV------------------ ->[subseq from] Possible beta-lactamase family protein n=1 Tax=Synechococcus sp. BL107 TaxID=313625 RepID=Q067T7_9SYNE -------WIQQAATQPDLQVSAYMLILDDGRFA-QMNAHRPMPAASSIKTPILLAVLERID -QGTLQWNEPLTLTKELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGQ -DAINARFQALDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGESLGPRSRD -LFREVMATSVT-NTLLPTGLMRGYRVFNKTGDIGT-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTEMIRQLAAAMA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A3C1YU45_9BACT --dSLRNKIERIVHQNEGHIGVAVINLNSNDTV-MVNGKEKFPMQSVYKFPLALAILHQID -KEKLSLDQRIHISKSDLLPWSPLREKYPDGNITLDEILTATVAWSDNNGCDLLFRLVGGP -TMVDQYIRSLGIEGMAIVSTEEEMH----------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) TaxID=479432 RepID=D2ARC0_STRRD -------ALREAFDDADVEGFIHVRDVDGDAET-GLGADEPVVLASVFKVPIVLEYARQAA -AGTLERTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -GNLHATLRGLGLERTRLIGGCAELLGILDPERTTSGTPRETTTLLTRIWRDEAGPPEACA -EVRRIMGNQIW-PHRLSSGFGDEVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT -GSLRLPRADRVIGHAARVAIDH- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KFC1_9PSEU ---AIADEIEAVFAGAGARGFVHAREVGDGPEV-GVGADDQVVLASVFKIPVAVAFAREVA -AGRLDETDRTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRV-GQ -AAVDQVLADLGLARTRLVGCCEDLFAVVDPERTTSLTPREITTLLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRMSSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA -ESDRQPAVDSAIGEAARLAVAH- ->[subseq from] Class A beta-lactamase n=2 Tax=Muribaculaceae bacterium Isolate-002 (NCI) TaxID=2489215 RepID=A0A4Q0J1G6_9BACT ----LAGNIQDYADASGAEIGVAVIGSDGDTTV---VNDGYYPMNSVLKMFQALPAAKKLS -ERGVMLCDTVEVERSVLQQWSPMLTDYTDPVLPYARLFEYALAQSDNNACDILFERAASI -DETLAYWRQAGIGEFDIKWNEAEMHDAPVRSDDNRTTPLAAAKAISVMMPYCMTSSDYNT -SNIGMMLNCSTGKGRIPRPLETGAQVAHKTGTGFEDGVNDVAWILLPDGRAYTLAVFVKT -TPACMAQTEAMIADISRIVYDYy ->[subseq from] serine hydrolase n=1 Tax=Pseudoclavibacter sp. CFCC 13796 TaxID=2615179 RepID=UPI001300CEDB --------IVDSAAQHGVKMGIALGDLSGGESVaVGAADEEFKAASTIKIGLAAVIMRAVD -DGRWDLQTPVTVRPSDIVGGTGTLQGGAAATLPLGELLRLMITVSDNTATNVLIDFVGGL -DAVGVGLRALGIADADMHRKMVLSH---DARHENLITATGDMRLLERIHAGEMLSRAASD -QIIDWMRQQTV-NTKFGAVVP-RTELANKTGENVD-VSHDTGYLLTPGRE-VALAVMTSF -GPGTASAADRDVQDVARAVHD-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus cereus HuB1-1 TaxID=1053207 RepID=J9B8Q8_BACCE ------------------------------------------------------------- --------------------------------MILKELADASLQYSDNNAQNLILKQLGRP -REFQNSMREIRDAVTNTERFKSELNVVHPGDAHDTSTPKALATSLQNFTIGDVLSTEKRD -LLIDWMQRNTTGDNLIRAGVPGGWEVADKTDLESYGIRNDIEIIRSPNN----------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. NEAU-CX67 TaxID=2571143 RepID=A0A4U0QM80_9NOCA ---------------------------DDEDAV-SVGADELVVTASVYKLPLLVALCRAFD -AGSLSPTATVRINPADCTPPTGVSNFRDPVVMSWRDLALSMMTVSDNAAADLILGRV-GL -DGIDRVLAELGLLRTRIIGGTADVHRAYDPAFTSATTPREMTSLLDAIWTDGVVSADQAQ -FIRQVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAIFTRA -ARADLPVVDQAIGRAAHIAVT-- ->[subseq from] CubicO group peptidase (Beta-lactamase class C family) n=1 Tax=Rarobacter faecitabidus TaxID=13243 RepID=A0A542ZNW4_RARFA ------------AATKNVRMGISVTDLAGGDTI-TVGDQEPYKAASVIKLPLLALLMDLAD -KGQLSLDESVTIPASNIVGGSGTLRLREPLDITVRELMELMVQVSDNTATNVLIDRAGGF -DAINEYIDGLGYDTMWLGRKMI--HTAVPPLQENWLNSSEVTDFLVRLYDHDFLSASSSE -HIIDLMKGQLV-NTKFGAVIPRD-VLANKTGELGD-ASHDSGYILIDGRE-VALTATTAF -SAFTLAEANVYVQRAATFVYD-- ->[subseq from] serine hydrolase n=1 Tax=Gelidibacter mesophilus TaxID=169050 RepID=UPI0003FEB316 --kNLEKGLAELVKTFEGDVGIYVYNLKTDKEA-AINADTIFPTASIVKVPILIEVFNQIK -VGKLRYNDTLVYDAKRKYGGSGLMQFYKDSTTDLRTLTSLMITVSDNTTSLWCQELVGGG -LAINKTMADLGLTHTRVNSRTEGRTKDWEIYGWGQTTPREMASLLIKMRKRTLVDETSSD -EMYRLMTNSFYTDYSL-SQIPPYVQTAAKQGMVNK-SRSELVMVNAPHGD-YVFYIASKN -NTDEDNKAWQLQRTISAYLWHYf ->[subseq from] Secreted beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BS50_9PSEU -------EIGAVFANAGARGFVHARQIGGGPEV-SVGADDQVVLASVFKIPVAVAFAREVA -AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIFHRV-GQ -AAVDQVLADLGLERTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRKIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA -ESDRLPAVDSAIGEAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma agri TaxID=1987381 RepID=UPI0013DA8014 ---SLDRELTTALAGFHGTIGVYVRNLRTGETV-AINADTLFPTASMIKVPILCGLFDKIH -KGELAYDQQLVYRDSLHYDDGIVGSFKDGTKLALSKVAMLMITVSDNTGSLWCQALAGGG -ATINQWLDTNGFHQTRVNSRTPGRAANQAQHGWGQSTPRDMADLITYIRQGKAVSPDASE -EMYRNLGHQYW-DNDGLSQIPPDIKTACKNGAVNQ-ARSEVVFVHAPHGE-YVYCVMTKN -QKDETNEGFVALRNIAAILWHHf ->[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. dk485 TaxID=2560021 RepID=UPI001431CA46 -------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE -AGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF -GPINATIESAGVPRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYEAAFLSAASAE -HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV -RPDVQAVANPFLQRIGTAVHDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Lentzea waywayandensis TaxID=84724 RepID=A0A1I6F884_9PSEU ------------FAEAGVEGFVHAREIGDGPEF-CHGADDQVVLASVFKIPVAVAYAAEVA -AGRLDETERTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ -ATVDAVLDRAGLERTRILGCCEDLFTIVDPERTTSSTPREITTLLDAIWTDRVARPEACE -RVRAIMAQQIW-PHRLSSGFPADVQVAAKTGTLPS-VRNEAGVVTYPDGHSYAVAVFTRS -QSLDDPAADAVIGRAGRLAVDQ- ->[subseq from] Serine hydrolase n=1 Tax=Terriglobus albidus TaxID=1592106 RepID=A0A5B9ECM8_9BACT -------AIRGLVAAHHGKVAVYARQLNTGKVI-AVDEDVPVQTASVIKLTMLYEAMEQIR -DGKAKWDEKIVLKPGDAVSGSGVLTFMDPPKLTLKDVLTLMVILSDNTATNLAIDRF-GV -KAVNDRIHALGVKDTHFYKKVMKPATDQPKFGLGKTTAHEMATVMEKIGRCDLGGPSQDE -AICQTMLRNQFYRNTIPRYLEAGSAIASKTGSLN-AVRNDVAIVAAKSG-PIVISIFTWQ -NKTTDNEGEGTIARIAREIVQEw ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=A0A1I4SHB7_9PSEU ------------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ -GGRIGLDDEVELPA-QRVGGAGLLRLLRSVDISLRDLITLMIVVSDNAATNAVIDAV-GF -AAIRDCAADLGCTDTRVERRLMHHHEP----GRNETTALDQARVLDRLAGGTALPPELTE -HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGTD-RPQAVIAVLVDE -LTDE------------------- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. H219 TaxID=2492662 RepID=A0A3R8P0V0_9PSEU ---SVERRIRAVLADAGAQGWVHAVRLGAGEHElGIGADELVVTASVYKLPLLVALARAFD -AGVLDPRETIRLDPTSCTPPTGVSIFQDPVRMSWRDLGASMVSVSDNAAADVLLGAI-GL -EAVADTLADLGLDRTRVVGGTADAHAAYDPSYASATTPREMTRLLELIWADEVASPQQCA -FVRRLLGQQAW-MHRVRAGFPQGVRVSGKTGTIG-AVRNEVSVVEFDGESPVAVAVFTLA -ARADLPRVDAAIAECARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Parapedobacter composti TaxID=623281 RepID=A0A1I1KKM6_9SPHI ---KLQRALEDAAKNFRGDVGIFVRHLKTGKEA-AIHADTVFPTASIIKVPILVGLFDKIW -KKELDYRQELLYSDTLYYGGSGLMQFYKDSATDVSVLASLMITYSDNVTALWCQHLAGGG -QTINALMDRYGFVHTRVNSRTPGREDARRAYGWGQTTPREIAMLLTKIRLGEIVSQTASD -RMYRLMTNIYY-DEGALSQIPGTVASASKQGMVN-ASRSEVVLVNAPSGD-YVFSIMTKN -NTTHDNEASELIRTISSLLWNHf ->[subseq from] Serine hydrolase n=1 Tax=Kribbella albertanoniae TaxID=1266829 RepID=A0A4R4PQQ6_9ACTN -----NARIRATFADAGVRGWLHAVALDAPESTvDIDADTVVPMASVYKLPLLVGFCRLVD -EGELDPRERLTLDPSTRTPPTGVSLMADPVTMSLRDLAVSMMAVSDNAAADALLDVV-GL -DRLAELLQSFGLQQTWVRRGTAANLVVYEAANASATTPSDMTLLLRRLWTGELLSAAQTD -FAKATMRRQIF-QHRLASGFPDSIRVAGKTGTFG-ALRHEVGVVTLPAGDAYAVAVFTLT -ARSDQPRADATIGLAAQLAV--- ->[subseq from] Serine hydrolase n=1 Tax=Elusimicrobia bacterium TaxID=2030800 RepID=A0A3B9YJX0_9BACT --eSLQARMEALARAHRGQVRFYAKSLATGESV-ELDADEPVRSASTIKLGILVEAFHQAG -EGRLPLSGKVVLREEDKVQGSGVLKFLRAPLLTLEDVLTLMVIESDNTATNLAIDQV-GL -NAVNARFAALGLKNTRLYKKVYKPAEPLPPDQKEFGLGKTTAREMSRLMEEAARDERMTA -ILKGQQNRNMI-PRYIEAGLDGGAIVANKTGALD-AQRSDVGAVFSPAGT-ILVSAFTDG -NEDQENEAEGLIAQLAKTVFDSw ->[subseq from] Serine hydrolase n=2 Tax=Cupriavidus sp. TaxID=1873897 RepID=A0A356HK75_9BURK ---RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA -QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF -EGVNDWCDRAGLRQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCWLLRDGSLPAPLRD -FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG -FTDA-RTAQ-------------- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E6MLA8_9BACT --eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE -SDPGLLSKRIEMTEEVRTSGSGVLDVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM -GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA -RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY -GG----DGGAVIEAAQKAAYSYf ->[subseq from] Beta-lactamase class A n=1 Tax=Ktedonobacter racemifer DSM 44963 TaxID=485913 RepID=D6TNC4_9CHLR --------------ALSGEVACVVWSPSTPEPLyTLHASQRFPAASLAKLPILLTVARQVA -QGKLAWEMRYEVPAAMRVTSDGVLTDLSPELPTLSDLAYLMITISDNTASNILLDLA-GM -EHINAFMQELGLHVTRLERRFMDFTAR-QQGRDNWTNAEEMARLLAYLCSEAA---PERE -RLLSILLRQND-YTILPSSWSEEVPFAHKTGGLV-GVMHDAGILYPPGKAPLILVALTAN -QA-DTPHTRYTLSRLGKLIYENy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI000D59A408 -----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGSVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=UPI000B8309ED ------------QAELPGRVGFAAWDLTEREPV-LLGAERVVPAASTIKVLIMISALRAVQ -GGRIGLDDEVELPA-QRVGGAGLLRLLRSVDISLRDLITLMIVVSDNAATNAVIDAV-GF -AAIRDCAADLGCTDTRVERRLMHHHEP----GRNETTALDQARVLDRLAGGTALPPELTE -HALGVLAEQQV-RDRLPALLPVGANCWNKTGELL-GLRHDVGLLGTD-RPQAVIAVLVDE -LTDE------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudacidovorax sp. RU35E TaxID=1907403 RepID=A0A1N7D284_9BURK ------------------------------------------------------------- ----------------------------------------------------------NGP -ARVEAIRRAVDAKRTDLATTMDEAYDRYYRRDLNTTTLIAYGGMLERLVRGQVLPDPPRA -VLYKAMKHDIYTGYRLQAGLPRDHAFIHKTGTQHR-RACHAGVLDPDDLQKALVIVACTA -DLDEQKQAGPVLESVGRAIR--- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. XM-24 TaxID=1979185 RepID=A0A316JLL3_9SYNE ---ALSKRWAQLAAQYDLTVSGYLLVLDDGRFA-ELAPQRPLPAASSIKTPILLVALEDLD -AGKLRWDERLPMTKEVVGGGAGWMAKPVGTTFPFWEAANEMIRVSDNTATNLLIKRVGGK -AVINARFQALGLSSTVVNNWLPDLDGT------NTTSAYDLARSIALVDTGEKLSPRARD -LFREVMGRSRT-NTLLPLGMLMGVTVYNKTGDIGI-AYADAGLIELPDGKRAVAAFMVKG -PFND-PRSTNLIRAMA------- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A6A7LVA9_9CHLR --nELAADVVQRIAGLSGQVGVAIKELDTGRGT-SIDPDGEYEAASLYKLPVMYEVFKQRE -LGALAFDESLVFTQRYVDWDLGTLDRPVDSTITIDEALEQMITISDNSSAVLLTDRV-GA -LNINRDLLGLGLAHTRLVTDDLAM------------SPGDALTLLEMIARGHAVNPAASA -EMVDVMARQRV-NDRLPLLLPDSTVVAHKTGNLP-GVVNDVGIVYTPET-TFIIAVLIDG -TA-NEQAAAEAIADLALIAYRHf ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A2G4GM14_9BACT ---RLQVEVENLVKGHQGEIGVFIKELKSGKTV-AVNAETSFPTASIVKVPILIGIMNKIN -NKVLDYHQKLTWYDTLNYDVDIVAYLKPETQIELSKVMMLMITISDNTASLWLQRVAGTG -TVINALLDSLGYAHTRVNSRTPGREANRTEYGWGQTTPIEMAQIYEDIVNGKVISREVSN -RMLRIMGRQYW-DGEALSAIPPDIYVAAKSGAVDA-SRSEV--LYVKGKRPYILSVFTKN -NKEDANEAWELTRSLSKLVWNYy ->[subseq from] Serine hydrolase n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A149ZQK7_9NOCA --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL -ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroides sp. KCTC 15687 TaxID=2447885 RepID=A0A401LUF6_9BACE ------------------------------------------------------------- --------------------------------MSIADLLRYTLQQSDNNACDILFHYQGGP -KAVNDYIHSLGIRDCAIVATENDMHQDLDLCYQNWSTPLAAAELLEIFRKKELFANKYKE -FIYQTLVECQTGQDRLVSPLAKGITIGHKTGTGDRNGCNDIGFVTLPNGRSYSIAVFVKD -SEENSQTNSKIIAEVSRIVYEY- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. BJA-103 TaxID=1911175 RepID=A0A2N8MT44_9PSEU ---ATTDEIEAVFAKAGARGFVHAREVGGGPEV-CVGADDPVVLASVFKIPVAVAFAREVA -AGRLDETERTRVVARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYRRV-GQ -EAVDRVLADLGLARTRLIGCCEDLFAVVDPDRTTSSTPREITELLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -DSDRLPAVDSAIGEAARLAVEH- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus xianganensis TaxID=1507289 RepID=UPI00132297D3 --------------------GLRVTDLNGTELV-AWNAEWVFPAASTIKVPLLVFALQEAQ -AGRLDLSARVTVRPGDRVPGAGVLHDLDGGLLTWRDVLTLMIVVSDNTATNLVIGRL-GV -GTVNAWLAAQGLTGTRLVGKLEQRNEAQRRGERNATTARDQTALLRVLVGGELLDGTHTA -LALDILGRQQY-RDLIARHVPCGYRSATKSGELL-GVHHDVGVLFTP--RPLLVALLSEG -GADPRE----------------- ->[subseq from] Putative beta-lactamase n=2 Tax=Synechococcus sp. RS9917 TaxID=221360 RepID=A3Z7S2_9SYNE ---ALSQRWRALAAEKDLQASAFLLKLDDGRYA-ELSPDTALPAASSIKTPILLVALELLD -AGDLSWNEPLTLSKTTVGGGAGWMASPLGSRFPTHEVATEMIRVSDNTATNLLIERVGGK -ELLNERFNALGLSATVVNNWLPDLEGT------NTTSARDLARSIALVDTGEVLSTRSRD -LFREVMATSRT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRAMAAAM---- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8QT65_9BACT --dSLQSRVAARLDRLXAIXSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA -SGRLDFGERYTVGPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -DRVNALLQNEGFSQTRLKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA -EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYEGG-PSIVSVFTNQ -NTGDFFDLEATLGLIAEDIVEAw ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A3D4EUJ7_9BACT ---TLATKLETRVAELDCEVGLYVQHLKKDHSV-LINADEVFPAASLIKVPILASLLNKVE -RGELGYQDKLIYTKDRLYPGEDLLGSFANNELTLKKLVFLMITTSDNTASLWCQELAGTG -TTINTWLKEKGFLRTRLNSRTPGRAAARGRYGWGQTTPREMAQLLIHIRDRKLVSAAADE -EMARIMGRSYWDGEAI-SSVPPSISTMSKQGAVN-ASRSEVVLVHAPHGD-YVFCIITKN -QKKHDNEGFSLLRDISRILWEHf ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=A0A2P7ZJ36_9ACTN -----AARLDAAFADAGVTGWLHAVDIDSEAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. WH 8101 TaxID=59932 RepID=A0A4P6L9F5_9SYNE ---ALSQRWRALAAEKDLQASAFLLKLDDGRYA-ELSPDTALPAASSIKTPILLVALELLD -AGDLSWNEPLTLSKTTVGGGAGWMASPLGSRFPTHEVATEMIRVSDNTATNLLIERVGGK -ELLNQRFNALGLSATVVNNWLPDLEGT------NTTSARDLARSIALVDTGEVLSTRSRD -LFREVMGTSRT-NRLLPGGLLKGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRSMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000E168597 -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKYGKMTWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P7ZBE9_9BACT --eTLEENLQQRIADFNGDAGVFVHHLPTGREI-SIQGDTLFPTASMIKVPLAVRIAELVE -DGSLHYDSLHTYEDRLYYPGSDLVASMKAGEIDLRKMVFLSLSFSDNTASLWMQELGGTG -TMVNEAMARLGLEHTRVNSRTEGRQEDFRRYGWGQTTPREMTRLMEMIYRGEVINPERSE -ELYRLLSKTLW-DGTALAVIPVTVNVASKQGAVS-ASRSETAVVNAPSGD-FVFTVITKN -QQDDDNEGFELIRDVTRLLWEAf ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus rekensis TaxID=937927 RepID=UPI0011239ECC --nELETALRALTKEVASKFSIAVH-TDEG-SI-AINVRTPRKAASLAKLFILGEAYQQVE -ATQISLDKLVYITPKSMVEGSGVITYLTDAHFSYQNLLELMIIVSDNTASNILLDTI-GM -EYINHFATKIGCNHTSLQRKFMDQKSHL-QGNENVTTSADIICLLKLFSRNDFFSNDSRK -QILNTLGNQQF-NSKLSTYINTSIKIYHKTGELHS-VEHDAAIMEANGN-VLEVAVLTDG -WE-NNGDASKYMAEIGRLLMNY- ->[subseq from] serine hydrolase n=1 Tax=Longispora albida TaxID=203523 RepID=UPI0003617514 --eDLRHHLGSLFAGAGVTGCLHAIDLDNGREA-GLGADTPVLMASAFKLPLVLALFRAAD -TGLADLAGQVRLEPGTRTSGPTGIGAMTGPVMTLRDLAHQALSVSDNAAADAIADHI-GL -GALTATAEAAGMAATRIAEICRDVAATLDLTASNRTTARDCTTLLAGIWKDTAASPGSCS -AIRHLLSLQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEIGVVEYPDGGRYAIAVFTRS -AALNLPRADAVIGTAARTAVEY- ->[subseq from] Serine hydrolase n=2 Tax=Clostridium perfringens TaxID=1502 RepID=A0A317TD26_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINKTIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Omnitrophica WOR_2 bacterium RIFCSPHIGHO2_01_FULL_49_10 TaxID=1801852 RepID=A0A1G1NFT2_9BACT --------LEREVAAFKGEAAIVVKDLDTGSEI-AFNKYNKYPSASLVKIPIMFAAFSAAQ -EGRLKLDKAVAVKAASKTGGSGVLKNFTPGTVTVKELIELMITGSDNTATNMLIDLL-GF -DYLNTYFTKIGLKSTNLSRKMMDFDHR-KKGVENYSTADDMSILLEKLYRNELFNEEITK -QCMAFLKNQRH-NDRIPA------------------------------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. BL107 TaxID=313625 RepID=UPI0002E4CE7F -------WIQQAATQPDLQVSAYMLILDDGRFA-QMNAHRPMPAASSIKTPILLAVLERID -QGTLQWNEPLTLTKELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGQ -DAINARFQALDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGESLGPRSRD -LFREVMATSVT-NTLLPTGLMRGYRVFNKTGDIGT-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTEMIRQLAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Lacrimispora aerotolerans TaxID=36832 RepID=UPI00054F0BBB ------AEMVKRLEQLPGKVSFYFENLMTGETM-VYHEQAPMMAASVIKLFVMTSVFEGLE -RELFQPDQMFEIKRADCVPCGALTYLHNGIQVTLMDLVTLMIIFSDNTATNVLVDFM-GM -EFINETISRLGFEKTVLQRKMFDLEKS-KQGIQNYITAGETGRLLNMMYHGDLVSRHASE -RMVSIMKNQQL-SGKIPFYLPDRPKIAHKTGEDT-GISHDVGIIYGK--VPF-IVCYCGN -ET-DTPCFERFMAELSLELYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2541 TaxID=2512217 RepID=A0A4R2IHD5_9ACTN -----NARVRAVFEDAGVRGWLHAVALDEPSATvEVDADDIVPMASVYKLPLLAGFCRLVD -LGEVDPTEQLTLDPSARTAGPTGLSALADPVMSLRDLAVSMMTVSDNAAADALLDLV-GL -RRLASMLESFGLRRTWVRRGTAGHLRVYEAANASASSPRDMTLLLRLLWAGELLSAEQTS -FVQATMHRQVF-QHRIASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFALAIFTQA -ARGDQPRVDAAIGEAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium wangchenii TaxID=2541726 RepID=UPI0014319951 -------------TAAGIDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE -DGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF -GPINATIEAAGISRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYESSFLSTASAE -HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV -RPDVQAVANPFLQRIGTAVHDY- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Hydrogenedentes bacterium TaxID=2030809 RepID=A0A3M2EVD8_9BACT --------LTRLLADSPAKVSVVVCDPRNGWRF-EYGSDEIVRAASVIKLPILVALFRMAE -RGEITLQTRYHLREKDRTGGSGRLRFLPFRHFSLRELAERMIRDSDNTATNAIIRIV-GN -KKLNREFVRMGFKSTRLRHRILASPK------DNPTTAEEISRLLLELENGRLYSDTSRR -ELLAILETCSN-RERLARYLPESLPVPHKTGTLRD-VVHDAGILPTRGG-PLVVVALTTQ -VPR-RRDAARWIARLGGTLY--- ->[subseq from] Beta-lactamase domain-containing protein n=1 Tax=Microbacterium sp. dk485 TaxID=2560021 RepID=A0A4Y9PXP2_9MICO -------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE -AGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF -GPINATIESAGVPRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYEAAFLSAASAE -HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV -RPDVQAVANPFLQRIGTAVHD-- ->[subseq from] Beta-lactamase n=1 Tax=Fusibacter sp. 3D3 TaxID=1048380 RepID=A0A1B6B9D2_9FIRM ---TLSSRIKAINYSFSGTMGVYANDF-KGNTI-EMHADECFETASCIKVPILATLLRRVH -EGKINLKDKISYTQENYVNGSGILRALSMGLLSILDFATLMIIVSDNIATNTLIELL-GI -DTVNETCEMLGLKVTRLHNKID-FEAY---RQLGTTTPREYAKIFELAYEKKLWNAELSD -VFVEILKKQHY-NTMLTKDLTPYISIASKSGSMD-ACRNDGGIFYTPYGG-YAITILTKE -FRYSEHESYQFGPKVSRLILDHy ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. KC345 TaxID=2530371 RepID=A0A4R4QRS8_9ACTN ---DVAQRIEAEFRSAGVTGFLHVTDIDTGREV-AIRAGEPVVLASVFKVPLLVTFHRQAA -GGLLDPAEPVTLRPRDRTAPTGVSGMQDEVRMSLRDLTFLMITVSDNAAADTVLDRV-GR -DAVNATAAALGLHDTIVEVSGRELHEALDPMRTSRSTPRDMTRLLSMIWRDEAAPPDGCA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS -PLAVLPRADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. AK53 TaxID=1406873 RepID=UPI000A394BAD --kNLQNGLRELVNNFKGEVGVYVYHTNRNTEA-AINADTIFPTASIVKVPILIGIFDKIN -NGELSLNDPLVYDAKRAYGGAGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELAGGG -ESINALMDNLGLQYTRVNSRTQGRTKDWEKYGWGQTTPREMASLLIKIRNRNLISEASSD -EMYRLLSNSFYTDYSL-SQIPPFIQTAAKQGMVNQ-SRSELVMVNAPTGD-YVFYIATKN -NNDTKNEAWQLQRKISAYLWRYf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E7JRD2_9BACT -------AMDRLAAEFDGRMGFYVEDINSGVAH-GYCADERFPTASVCKVCVMVELFRQVA -EGACTLGDRHRLAGSISRHGSGTLKWAVDGPLSLRDYCRLMMAISDNVATDALIGLL-GL -EAINATMQSLGYPNLHTGATLTRFHYFADDPANNLAASGEMGRLLGRLCRGEIIDAEASV -GMVEMLGLAAN-RDMIPRYLDPGVDIAHKFGSSGR-IKADVGIVYLPGG-PLVVSAFALA -AA--AADGAAAIAELTRLAV--- ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A5Q4FAE0_9BACT ---SLKMDIERFLESREGTYAVWFEHLQQPELSfSVNPDTIFHAASTMKTAVMAELFRRAE -LGDLSLSDSIRIENRSIVDGSEFQERRAGEMATLGDLNHAMITYSSNIATNLILQIT-GA -AQTTQTMQNLGAGGVEVIRGLYDMKA-FELGLSNRTTARGLGTLFRRIAEGNAISPEMDS -LMISVLKDQFY-RDVIPSLLPESLPVANKTGFIS-GVIHDSAIVWLPNGDSYVLIFLSKE -LP-DNDIGTETGALVSEMIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter cocois TaxID=1747507 RepID=A0A365YUF8_9PROT ---TLSDDIAKTIQGQPGHFAVYAAMSGQPPQV-CLNCDDFIDAASTMKLFVMDAAYDSFT -KGTLHPQDVIVVHNRSLVGGSFALYAAIGRPVAVSELLRVMIQYSSNLATNLMIERI-GV -PYIRAIVAAQHLDGIRFGRMIEDYDAN-DQGIHNQVSARGLGLFLQKLDHGDIVGPAQSQ -AMIDIMKGQKF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNRISRQVHDSf ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. 17J42-9 TaxID=2492393 RepID=A0A4Q5LQJ4_9BACT ---KLKAKLQQAIQGFNGEVGIYVRNLKTNKFV-AINADTVFPTASMIKIPIMIGTFDKIR -QSTLKYEQELVYRDSLKYDDGIVGSLKDSTKIPLSYVMMLICTISDNTGSLWLQALSGGG -KRINAILDSLGFQVTRVNSRTPGREANRSKYGWGQTSPKEMVNLLTMIREGKVISPAYSD -RMYRNLGRQFW-DTEGLSQLPANVKVATKNGAVNR-SRSETALVHAPHGE-YVYSIITKN -QKDEENEGYELLRKVGALLWHHf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_02_FULL_39_11 TaxID=1798382 RepID=A0A1F5ZY13_9BACT --kELLNEIHSLTPPALGTYAVYIYDINSGEEL-GINEQMIFTAASLNKLAILAVLYQEAS -DNQIDLDKIIVPQKEDIQDTGSIRYDPPNTPYSIKTLAKLMIEQSDNTAAHLLGNIVIGL -PQIQKQIEDWDLLQTDMV--------------NNKTSAKDMALLLRKIYKGEITSRPYTL -EMLEFMNKTDF-EERIPTGIPRDVKTYHKTGDEI-GKIHDAAIVELPNK-PYILVVLSSE -IK-DEEKAKQTIAQISRNVYE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia gamkensis TaxID=352869 RepID=UPI0007A45883 ---------QEIFRTAGVEGWIHAQCVDCGAEA-GTRADEPVVLASVVKVPLVLEFARQVA -AGQVDPADRVRARAADRLGGVGTAGCADDVELSLRDAAYFALTVSDNTAADLLFDRV-GL -DNVRSLLRELGLTATRVVGPPRAVVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR -WVRDLMRQQVN-WYRLAAAFPPEVGVWAKTGTLP-GVRNEIGVVEYPDRKRYAVAVFTRA -ATQRLPEVDRAIGAAAVAA---- ->[subseq from] Beta-lactamase n=2 Tax=Synechococcus sp. KORDI-100 TaxID=1280380 RepID=A0A076H662_9SYNE ---ALSEKWKQLAAQKDLKTSAYMLILDDGRFA-QLEAERPMPAASSIKTPILLASLELVD -SGDLQWNEPLTLTKELIGGGAGWMAKPVGSRFPTFEVATEMIRVSDNSATNLLIERVGGQ -AAINARFQALGLPATEVNNWLPDLDGT------NTTSARDLSRSIALVDSGETLSPRSRD -LFREVMSTSVT-DTLLPTGLLQGYHVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG -PFN-DPRSTNMIRALAKAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. LRa12 TaxID=2563107 RepID=A0A4S2WG49_9ACTN -----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNCTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID14478 TaxID=2706073 RepID=UPI0013DBB5A9 ------DRIRAAFADAGVSGRLHALDIDAGTHL-GVDADDLVCTASVHKLCLLVALHERAS -SGDLVLTQQVDCPPHGRTPPTGVAAMLDAARLSLRDLAYLMMAVSDNAAADLLLAHV-GL -DAVNATTSRLGLDRTQAVHTFGAMLAALDPARTNHSTPRDMTRLLRAVWRDEACPPDHGA -AIRRVMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AQGTLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF65C3A -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTIMIIVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGVDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQATNKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella antibiotica TaxID=190195 RepID=A0A4R4ZSG8_9ACTN -----NARIRAVFDDAGVRGWLHAVALDDAASTvSLDADAVVPMASVYKLPLLAGFCRLVD -DGELDPRAQLTLEPATRTPGPTGLSLLADPVMSLRDLAVMMMTVSDNAAADALLTVV-GL -ERLAELLESFGLQQTWVRRGTAANLLVYEAANASASTPRDMTLLLRRLWAGELLSAAQTD -FAKATMQRQIF-QHRLGSGFPHDIRVAGKTGTFG-ALRHEVGVVTLPAGDAYAVAIFTRT -ARVDQPRADAAIGLAAQLAVN-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-1448 TaxID=1463883 RepID=UPI000B00402F ----TPARIRAVFAEAGVTGWLHALDIDSGAQL-DAGADQLVCTASVHKLCLLVTLHQLAA -TGALDLGEHIECPSAGRTPGPTGLAAMLDPVMSVRDVAYLMMAVSDNAAADLLLGRV-GL -DAVNRTTQRLGLTGTHAVHTFGELFAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA -AIRRILGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRT -AHATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. AM23-21AC TaxID=2302961 RepID=A0A372X3B9_9FIRM --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVAVTAEDILSDTGVFVDGPGM-HPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYAETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] serine hydrolase n=1 Tax=Veillonella sp. CHU740 TaxID=2490950 RepID=UPI000F8D66FA ---KARQKLSQISDSIQLAPYESVYIGYHGESV--VKQSKPMRAASMIKVYILGYLFEEVE -AGRISLDETILLQRSDQVGGAGILSGYSGTALTIDELAKLMITVSDNTATNILIHRL-GM -ENINTYIVKHGYADTKLQRNMMDLT-AIEEGRENYTSAKDLGTWFMNLLDGKNMSGASRE -KMLTYLLGQTD-TETFNEALP-NRSIAHKTGELG-GVYHDGGIIFQNN------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Leucobacter komagatae TaxID=55969 RepID=UPI0005AC1FF3 --dTLTARIAQVAEDAGVFAFAHARDIDTGAEV-GFDSDAPTVTASVFKVPVLVEYVRQVS -AGELDPAQRVRFLPADATLGPTGLSVFSDEAWSLRDVATSMITVSDNAATDIVTGMV-TV -DRVNQTMRELGLPGTQLTGDCARIFEAATPEKTNRTTPREATSLLQQIWTDAAASPEACA -EARRILGLQVW-PHRLSSGFPDDVKISGKTGTLGM-VRNEIGVVEFPDGTRHAIAVFLRG -KTSRNPAADRAIGDIARLLSD-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura darangshiensis TaxID=705336 RepID=A0A4V2YXP0_9ACTN ---DVAERIRAEFRSAGVTGFLHVVDMDTGREV-AVAAGEPVVLASVFKVPLLVTFHRQAA -GGVLDPSEQVTLRPDERTAGSTGVSALLDEVMSLRDLTCLMITVSDNAAADAVMDRV-GL -DAVNAAAAALGLRDTVIEVDGRGLHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGARYAVAVFTRS -PTAVLPQADAVIGTAARMAVE-- ->[subseq from] Beta-lactamase n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A2E5HXM0_9CHLR --eQLNERVAEMIYAFPGIAGCSVKSMVDGNSL-AVNGDVEFPIASTMKIPILLQLLMRDE -NGELDINELVEITPEMIYPGSGVISYLEGPVLSILDIAILMIIVSDNTSTNLCIDYA-GI -EQTNDMLRALGVDNITLRRKMQDTESVIAN-RENVGTPDDCVLLLEHLYNGRP-SKKSAE -RCLSVLRKTKK--SLLNRVIPPDVPLANKPGGMAQ-VRCDAGIVYLSR-YPYAVSIQTSF -AEIGPEEQENYMVELGL------ ->[subseq from] serine hydrolase n=1 Tax=unclassified Clostridium TaxID=2614128 RepID=UPI001122EBD0 -------DIKKFLDSRIGDYSFYFEDLSSGYVY-AMNENVRMPAAGSMKLPIAIALFKEVQ -PGKIDINMKVKVKAEDMVYSTGILHEFSERDYSVKELLTAMLLHSDNTAANKLIDII-GM -DRINEIIRDMRLANTVLNRKSIDERK-SHSEVQNYTSAMDLSKCWRILYNETFVDKENSR -IIIDILKRQQL-KNKLSYYYPERIKIANKTGDIDN-VENDTALMSINKG-SFIITVMSSN -LPN-NVYGQITLARVGKMALD-- ->[subseq from] Beta-lactamase TEM-12 n=1 Tax=Synechococcus sp. MIT S9508 TaxID=1801629 RepID=A0A164B477_9SYNE ----LSERWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD -AGRLSWNEPLQLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ -EALNARFNALGLSATKVNNWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSIT-NTLLPRGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFN-DPRSKELIRKLAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A1I0I722_9FIRM ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEAFETASTIKTYILACLFDEVE -KGNKSLEDMIEYKEEHVVDGSGVLPDLEPGALRVKDAATLMIIVSDNIATNMMIDYL-GL -ERINQCIKALGCKDTVLHNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE -KMLDILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIIMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] Serine hydrolase n=1 Tax=Pseudonocardiales bacterium TaxID=2201155 RepID=A0A2W6D408_9PSEU ----TARTIADTFERAGARGYLHARRVGGPGAL-GLDADEPVVLASVFKIAVALGYARCVA -EGRLDPRARTTIGRGDRVGGIGTAGCADDVQMSWRDVARFMLTMSDNAATDVVLRQV-GL -DAVHRALAELGLHRTRLIGGCAEILAALDPVRTTASTPSEMTSLLDAIWQDRAAAPAACA -EVRAIMAAQIW-PHRLTAGFPDAVRVAAKTGTLP-GIRKQVGVVEYPDGARYAIAVFTRA -REERQPAIDAAIGATARIAVEH- ->[subseq from] Uncharacterized protein n=2 Tax=Ktedonobacter sp. TaxID=1932716 RepID=A0A349M5Z3_9CHLR -----QASIEQELSTLGGHVACVVIRMTDEQELvSINADHVFPAASLAKVPLLIEVARQVE -FGMLCWETRYRVWEGARVASDGVIADLSADLPTVQDLAHLMIAISDNTASNMLLDIV-GM -DAVNATMSNLGLTDTRIERRFIDFEAR-KAGYDNWTTAADMALLYSFFFTE-LLP-GKKK -MLKMLLRQND--YTILPAYWGEKTPFAHKTGGLA-GIIHDAGILYAPTHTPLIIVIMTSE -QV-DEPLTRYTLARVGRIIY--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522YC23_9BACT ---------------------LHAREIGTGHEV-GLGADEPVVLASTFKVPVALEVFAQAA -EGGLDLSERVRVPVEGRAPGPTGLSVFSHEALSLHDLARSMITVSDNAATDVVCERV-GL -DRVAARLGALGLDEIVIPYDCRGIFAALDPLQTDRGTPRAMTRLLELIWTDTAGPAGACA -QVREVMAQQVW-PHRLTAGFPADVTLAGKTGTLPS-QHNEVGVVGYPDGRSYAVAVYVRS -ARFDQPLLDRAIGEAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis decaplanina DSM 44594 TaxID=1284240 RepID=M2ZQH1_9PSEU ---ATSDEIEAVFASAGARGFVHAREIGGGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDETERIRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -ESVDRVLADLGLTRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAEVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRLPAVDSAIGRAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4Z4V2_9ACTN -----------VFADAGVRGFLHAREVDGDAET-GLDPDEPVVLASVFKIAVALEYARQAA -AGEISRTERLTVTTADKDGGIGTSGCHDDVSLTLRDLAHFMITMSDNAATDVLLRRV-GL -DRVNGTLAALGLRRTRLIGGCAELFDAVRDPARTTATPREITALLSLVWRDEAGPPEACA -EVRGLMGEQIW-PHRLSAGFPDEVKVSGKTGSLW-GVRNESGVAEYPDGRRYAVAVFVRS -EVERLPHADAVIGRAARLAVEQ- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. E5N91 TaxID=1851996 RepID=UPI000EF57CDC -----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DSVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AIRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus benefaciens TaxID=453960 RepID=A0A2T2X7U7_9FIRM ------QRIQSVIGRFMGHVGFYAEHMMSHDSL-SYDSQIVMETASVIKIPIMAAAFQYLV -DHNESWETPLRIEPEDIVEGSGILRHLSPGLLPILDVITLMIIVSDNTATNMILRLV-GL -DTVNHFITQHGLAETKLMKRVD---FSIPG-PLGLSTARDMATLLTRLYQRTLVSAQASQ -AMWKILTQQQY-NTIMTRDLPYDVRIGSKSGSLQ-GVRNDVGIVTTPWGD-YVVAILSEK -AKHVDNEALVILPELSRIIFDYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0AZ97_9CHLR ------QSIAESLVAASGGFAEVVIALPSGEFIvDINGSEPMESASLYKLGIMVEVFVQRE -VGMLSFDDGVLLEPGYFVEGEDVFGYDIGAVYTVGTLLQAMITQSSNVAATALLATV-GN -ENVNATLASLGITNTQI-RWMPDPSAARADGALNVTTAEDMAWLYTLLLRGEVIAPEVSQ -EMLDLLAAQEV-NDRIPAYLPGGTVVAHKTGNLD-GLVHDAGVIYAPAG-PIIVVVLTED -IDED--VAIDMIAQIALAAYE-- ->[subseq from] serine hydrolase n=1 Tax=Arenibacter sp. JC631 TaxID=2608629 RepID=UPI00123D59B7 --kNLQNGLRELVNNFKGEVGVYVYHTNRNTEA-AINADTIFPTASIVKVPILIGIFDKIN -NGELSLNDPLVYDAKRAYGGAGLMQFYKDSTTDLRTLVSLMITMSDNTTSLWCQELAGGG -ESINALMDNLGLQYTRVNSRTQGRTKDWEKYGWGQTTPREMASLLIKIRNRNLISEASSD -EMYRLLSNSFYTDYSL-SQIPPFIQTAAKQGMVNQ-SRSELVMVNAPTGD-YVFYIATKN -NNDTKNEAWQLQRKISAYLWRYy ->[subseq from] Beta-lactamase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A381J151_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDIENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 62 TaxID=1827599 RepID=A0A3D9M0H1_9ACTN -----ARRITAAFTDAGVTGRLHATDIDTGAAL-GVGSDTPVPTASVHKLCLVATLYRRAH -LGFVDPTRPVDIPAEGRAPGSTGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNTTMAELGLTHTRAVHTMRELYEALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE -ELRALLGLQAW-THRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAAIGRAARIAVD-- ->[subseq from] Beta-lactamase n=7 Tax=Clostridium perfringens TaxID=1502 RepID=A0A2X3E4Y9_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A645DLR0_9ZZZZ ------------------------------------------------------------- --------------------------------------------MSDNVGCDILLRLIGGP -KTVNDFLISKGMKDTQIVYNEEVMQSDWKNQYENYTTMKSSNTLLKDFYQGKIISKESTE -FLLGVLYRTSTGTNKIVEQLPKSAKVAHKTGSSGTGAENDIAIITLPNGKTYALSIFVSD -SMESWETNCKIISNISKAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P2415 TaxID=1805471 RepID=UPI0009886151 ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AVHADETFETASTIKTFILACLFDQVE -KGNASLEDMMEYKREHVTDGSGVLAALEPGALRVKDAAAFMIIVSDNIATNMIIDYL-GL -DTVNRCIEKLGCRDTVLYNPIH-FDR---YDRLGTSTPRDYAGIFTRLVRGELISARADH -QMLEIFKKQHY-NSMITKDFPPFISVASKSGSMN-ACRNDGGIVFTPYG-PYVIVMFHKE -FSDAAHPAAVYGARVSRMILDQf ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A523GW54_9BACT --------------YHDANVAISIIDHSRNVVI-HGDGNRLFHAASTMKVPVMIELYRQEA -AGYLSLDDSLLVENQSIVDGSVYSYDKLGSFMTMRELAYNMITVSSNLATNLLIDRL-SA -DSVQATSERLGTLNAKTVRGVEDLKA-FDQGLSNSMTSRDLAILMEAIRTGIAVSPASDQ -EMVELLLSQFF-NSMISAGVPREAKVAHKTGSITS-VHHDAAIIYPPEDDSFVLVVMTDG -IE-DRIISSELGARIAAAAYK-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522YPR7_9BACT ---RLQKKIEAAVSGFQGDLGIYIKNLRTGKIV-AVNADTVFPTASIVKVPILIGIMDKIQ -KNELSFDSQLVYKDSLLYEGEDILGSFKADEIALKKVVMLMLTTSDNTASLWLQNYSGTG -TRINEIMDGLGFVSTRVNSRTPGRTNNRTQYGWGQTTPKEMGTLFEKIYRKELFSKEAST -KMLRLLGRNYWDEDEALSQIPPTIEVFSKNGCVD-ASRSEVLLVNAYKN-PYIFCIFTKN -NKTHENEAWTLARKISKLLWEYy ->[subseq from] Uncharacterized protein n=1 Tax=Microbacterium wangchenii TaxID=2541726 RepID=A0A6D1IAD6_9MICO -------------TAAGIDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE -DGMLTLDDIRTILPEERYEGSGILKDTFPQDVSIGRMLDLMITVSDNTATNKLVDVVGGF -GPINATIEAAGISRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYESSFLSTASAE -HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV -RPDVQAVANPFLQRIGTAVHD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI00016BDC15 -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000505EDAB ---AIADEIEAVFAEAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPSGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRQPAVDSALGEAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces klenkii TaxID=1420899 RepID=A0A3B0B282_9ACTN -----RGRIRAAFTEAGVTGWLHAADIDSGAQL-DVGADQPVVTASVHKLCVLVALHQQAE -EGLLDLSEQTVCPPPGRTPGPTGLAAMLDEVLSLRDAAYLMMAVSDNTAADLLLRRV-GL -DAVNHTTRRLGLTRTHAVHTFGDFLAVLDPAATNRSTPRDMTRLLGAIWRDEACAPEYAA -SMRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -SSAVLPPADAVIGTTARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. SGAir0479 TaxID=2567884 RepID=A0A4P8PV55_9NOCA -------RFAELFADAGVRGWVHAVPVRGAAAEtGLDADAPVVMASVYKLPVLVTFCRMVD -SGDLDPREQVTLEPEGRTPPTGISQFLDPVRLSWRDAVRSMMTLSDNAAADEVLRRI-GV -DRVNETMQTLGLHSTRVLGGTAQILQGYDPVLSSATTARDMTTLLSALWRGACASAEQSA -FMRAVTASQVS-TARLRSGFPADVTVAGKTGTLG-AVRNEVGVIEFPDGDAFAVAVFTRA -ARADLPKADAVIGQAARVAVA-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. C10 TaxID=2600577 RepID=A0A5C8K2I1_9ACTN ---------REVFEGAGARGFLHARDVDGDRET-CLDADEPVVLASVFKIAVLLEYALQAA -AGELARTERLTVTAADKDGGIGTSGCADDVSLTLRDLAHFMMTMSDNAATDVLLRRV-GL -DRVHATLARLGLRRTRLIGGCAELFAAVRDPARTTSTPREITTLLARIWRDEAGPAEACA -EVRAVMGRQIW-PHRLASGFGDEVRVSGKTGTLW-GVRNEAGVVEYPDGGRYAVAVFLRT -DKGRDPSADAVIGRAARLAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A127EIB9_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNH287 TaxID=1288082 RepID=UPI0009965FD1 -----------------------------SAQV-AIEPDAQLPMGSVYKVPLAVAFCRLAD -AGRLDPRRRITLEPGERVPPTGVSVLHDAVTLSLRDMVVLMMTISDNTSADAVLRAV-GP -GTVDAVCRELGLPDTHIRGGVVSTFHVYDPAYEASTTPSDMTRLLRAIWTGEAASGDRCA -FLREVMRRQPW-AHRLGSGFPDDVTVYGKTGTFG-AMRHEAGVVELADGSAYTAVVFTQA -ARSDLPRADAVIGAAARAAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Sphingobacterium psychroaquaticum TaxID=561061 RepID=A0A1X7J294_9SPHI --kKLEERLKKETENFQGDIGIYVQHFKKNTTV-NILADTIFPTASIVKVPILVGVFNKIN -EGSLTLRQPFRYDAKRVYGGSGLMQFYKDSATELSIMISLMLTYSDNVTSIWNQELAGGG -VEINRIMDQLGLVNTKVNSRTTGREQLWRKYGWGQTTPQEIASLMHLIRSGKVFNPQLSD -KMYRYLKNQFY-NERSLSQIPAEIATASKTGSVDD-ARGEVVYVHAPSGD-YVFSVLTKN -NKTDENEAEKITRKIASIIWNYy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. TLI_146 TaxID=1938858 RepID=UPI000C7095B3 ----AAARIREAFDQAGVTGRLHALDIDSGAEI-GSGGDQAVVTASVHKLCVLVALHEQAA -AGRLDLTEQLEVPLEGRELGPTGMAAMLDPVMSLRDAAYLMMAVSDNTAAELLLGRI-GL -DAVNATTARLGLAHTHAVHTFRELLAALDPARTNRSTPRDMTRLLSAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -ASATLPPADAVIGTTARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces niger TaxID=66373 RepID=UPI00069A906E -------TIREMFADAGVRGWLHVAELHREARV-TVDPDEPVPMGSVYKVPLMVAFCRLAD -AGELDPALRVTLEPSHRVAPTGISILQDAVSMSLRDLVVLMMTISDNTAADAVLRAV-GS -TVVDGVCRELGLPDTRILGGVAGTWAVYDPVSKASTTPSDMARLLRAIWTGAAASAERCA -FMRDVMGRQPW-RHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=UPI000A456F28 ---AARTRIAAAFADAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA -AGRIDLTRQVDVPAAGRTPGSTGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL -DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATTLPAADAAIGTAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Antarcticibacterium sp. PAMC 28998 TaxID=2585771 RepID=A0A5B8YGN6_9FLAO ---TLEKELREIVKDFKGLAGVYVYNLKTRQEA-GIHADSVFPTASVVKVPILAGLFNKIE -KGELSLFDTLIYNKERVYGGSGLMQFFKDSTTDLRSAAALMITYSDNVTSIWSQELAGGG -EEINNLMEGLGLEHTRVNSRTPGREDLWKKYGWGQTTPREMAGLLIKMRNRELVSEAASD -EMYRMMTNSFY-TDYALSQIPPYVQTAAKQGMVNQ-SRSELVMVNAPGGD-YVFYIATKN -NEDTENEAWVLQRKISAFLWNYf ->[subseq from] serine hydrolase n=1 Tax=Vulcanococcus limneticus TaxID=2170428 RepID=UPI000B9994AB ------KKWAALAAVHDLKASAYLLVLDDGRFA-QLQSELPLPAASSIKTPILLAAMEDLD -AGRLRWDQPLTMTKEVVGAGAGWMAKPVGTRFPFHEAATEMIRVSDNTATNLLIKRLGGK -TALNTRFQALGLPGTVINNWLPDLEGT------NTTSAHDLARSIALVDTGEKLSPRARD -LFRQVMGSSRT-NTLIPLGLLQGVTVLNKTGDIGI-AYADGGLIELPNGQRAVAAFMVKG -PFND-PRSTDLIRAMAAEVA--- ->[subseq from] serine hydrolase n=1 Tax=Lacrimispora amygdalina TaxID=253257 RepID=UPI000BE2B6EC ---TLEKRIKAEIMSYDGRMGVYLNDFH-GNEI-ALGQDEKYETASTIKPFILACLFDEVE -KGNKSLEDLIKYKEEHVVDGSGVLAALEPGALRVKDAAVFMIIVSDNVATNMMIDYL-GL -DTINRCIKELGCSDTVLYNPIHFDQY----RRLGTTTPRDYGSIFTRLVKGELISPEADA -AMLEILKKQHY-NSMITKDFPPVITVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE -FSYPAHPATVFGARVSRMVLDQf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TLI_146 TaxID=1938858 RepID=A0A2N3W5K4_9ACTN ----AAARIREAFDQAGVTGRLHALDIDSGAEI-GSGGDQAVVTASVHKLCVLVALHEQAA -AGRLDLTEQLEVPLEGRELGPTGMAAMLDPVMSLRDAAYLMMAVSDNTAAELLLGRI-GL -DAVNATTARLGLAHTHAVHTFRELLAALDPARTNRSTPRDMTRLLSAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -ASATLPPADAVIGTTARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A520E5E6_9SPHI --qKLQQKLNDLVKGFNGDVGIYVKNLKTGKIA-SVNADTIFPTASMIKVPITCGVFNKIE -KGELDYHASLTYCDSLLYAGEDILGSFKDSEIALSKVLMLMITTSDNTASLWSQLLAGTG -TAINEVMANNGLKDTRVNSRTPGRRENQKQFGWGQTTPKEMATLLTLIRDGKMISPAASE -RIYRNLIRIYW-DTEALSQIPPTVQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN -QKNYTNEGWTMIRNLSNLLWNYy ->[subseq from] Beta-lactamase class A n=1 Tax=Ohtaekwangia koreensis TaxID=688867 RepID=A0A1T5JKG3_9BACT ---VLQQKLQELVKGFKGDVGIYVRNLKTGKIA-AIDADTLFPTASMIKVPITVGMFDKIE -KQEIRYDSMLTYKDSLLYEGEDLLGSFKDGEIALKAVLMLMITTSDNTASLWCQLMAGKG -TTINAWLDNNGFKQTRVNSRTPGREMNRTKYGWGQTTPKEMSELVVRIREGKVISPRVSE -RIYRNLIRIYW-DTEALSQIPPYVQVASKQGAVNQ-SRSEVALVNAPHGD-YVFCVITKN -QKDENNEGWVLIRKVSSLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Bordetella sp. J329 TaxID=1977852 RepID=UPI000FD79110 ---RLAQGLAPILTSTQARVTMAVHTLDGTPLF-EREARTAMPSASLIKVPILLLLLEQVA -AGRWPLDHMLSLEHTERVGGTGILNQLPSVRLQLEELGRLMIVLSDNVATNALIDWL-GL -DSVTQWCQRAGLPQTRLERRMMDAQAR-AAGRDNWTSAADACAALLWLLRSSSLPAPLRQ -LGLQMLADQRE-QSHFGAALPAHAKLANKTGQLH-GLRHDAGILSAGG-QSVVLAVLADG -FTDP------------------- ->[subseq from] Beta-lactamase n=2 Tax=Lactobacillus perolens TaxID=100468 RepID=A0A0R1N785_9LACO ---EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAK -NGDLNLADTYTVTGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIDYLGGL -DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN -QMMAIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIIQGDRH--IFVAVVMSQ -NGHSG------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces tendae TaxID=1932 RepID=UPI00133106C9 ---ATAARLDAAFADAGVTGWLHAVDIDSGAQI-GAGADQPVCTASVHKLCVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPAEYGA -AVRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536K880_9CHLR ----------ALRRPFSGRLGFWALNLRTGELL-EHNAEEIFPSASTIKLFVLRELYRQAE -AGRLDLDRSVVMQHKDVTTGSGVIKDLTTGLLSLRDAATLMITVSDNTATNLLVRLL-GT -RAINQGARQAGYAGTRCAGRIFKGNRM-----RSLSSPRDLGVFMANVALGRELSRAASQ -AMLDTLKREQY-ANIVGRLIPTRWLLASKSGSLV-GVRNDAAYVKGPGV-RYAIALMSSD -CEDEDNEANLVLARLAADIHAHf ->[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI00049326BF ------PDIAALFTEAGATGFLHAREIGGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS -DAVNRVISDLGLRHTRLVGCCEDLFAAVHPAKTSHSTPRDVTTLLYALWTDTAATAEACR -QARDIMAQQIW-PHRLSSGFPPGVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASERQPLVDASIGR--------- ->[subseq from] Serine hydrolase n=1 Tax=Cupriavidus metallidurans TaxID=119219 RepID=A0A2L0X380_9BURK ---RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA -QGHLQLEQRFSLDGLERVGGTGILNQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF -EGVNDWCDRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCWLLRDGSLPAPLRD -FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG -FTDAGGDGAQWLAEAARIVA--- ->[subseq from] Serine hydrolase n=1 Tax=Lacrimispora algidixylanolytica TaxID=94868 RepID=A0A419T6E8_9FIRM ---TLEKRIEAEIKSYDGIMGIYLDDL-HGTTI-EIKAEETFETASAIKTLILACLFEEVE -KGTVSLEDMIEYKKEHSVDGSGVLLAEPGARLRVKDAATFMIIVSDNIATNMLIDYL-GL -ATINRCIKGLGCMDTVLHNPIHF-D---QYDRLGTSTPRDYASIFIRLTKGELISPKADQ -MMLEILKKQHY-NSMITKDFPPYFTVASKSGSMD-GCRNDGGIVFTPYG-PYVIVMFHKE -FSDAAHPATLFGARVSRMILDQy ->[subseq from] Beta-lactamase class A n=2 Tax=Arachidicoccus rhizosphaerae TaxID=551991 RepID=A0A1H4D2N8_9BACT --kALQEKLSVLLDQFHGTAGIYVENLRTGKFA-GVHADSIFPTASIIKVPILAGVFSQIK -AGKLSYNQELTYDTSRTRGGSGLMQFFKDSSTSLDILLSLMISYSDNVAALWCQQLAGGG -TQINQLLNDYGFKSTRVNSRTPGREEAYKEFGWGQTTPREMATLLKLIRQQKIVDPASSD -CMYRQMSHIFY-DGYALSQIPPYIQTASKQGMVDD-SRSELVMVNAPHGD-YVFYIATKN -NQDQRWEKDALARAVSSLLWHY- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A7B4T6_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGRTV-EIGADEAFETASTIKAFILAALYLQVS -RGKASLDERITYEESQFVDGSGMLRAGVGAALKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLH-FDR---YRDLGTTTPRDYAALFAQVAKGTLVSKEASA -EMLAIFRQQHY-NTMLTHDFPERIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Beta-lactamase n=2 Tax=Lactobacillus bifermentans TaxID=1607 RepID=A0A0R1GKJ0_9LACO ---KVRQTVQQTVGHLSGDTSVYIAPTRGTGAV-SIRPQ-PQRSASSIKLFILTAAYAH-- ---HLDLQATHTLTAAEQVGGTGVLQTMAAGTLTYQEILTKMITDSDNTATNIIIDQLGGV -TKVNQEIQALGATQTTLRRKMLDTQ-ALANGKDNTTTAKDMGVLLTKLYNHQCLGTTDDN -AILSILAQTKN-HEKLPAQLPTGTTIYNKTGEYDYGVQNDAALIKNNKGA-FVAVVLSQN -GQQA--Q---------------- ->[subseq from] Beta-lactamase n=1 Tax=Flavihumibacter sp. ZG627 TaxID=1463156 RepID=A0A0C1IAC6_9BACT --rKLQKAIESLVEGFKGTVGIYVKHLPSGRSA-QINADTLFPTASMVKIPIMIGIMDKIH -KNELQYHQPLVYNDSLLYAGEDILGSFKSGEIQLAKVLMLMMTTSDNTASLWLQSMAGTG -TRINQLLDSMGYSATRVNSRTEGRRGHWEQYGWGQTSPREMVRLLEQIYQRKMINDTLSE -RMLRLMGRNYW-DEEAISMIPPEIFVASKNGAVD-ASRSITMLVMAPHG-PYLFSVITKN -QPDT------------------- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T315_9PSEU ---TISDEIEAVFAKAGARGFVHAREIGDGPEV-DVGADDPVVLASVFKIPVAVAFAREVA -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMTQQIW-PHRISSGFPADVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -GSDRLPAVDSAIGEAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ERV7 TaxID=1322334 RepID=A0A197SKR3_9ACTN -----LARIREAFDEAGVTGWLHALDIDSGAET-GVGGDHAVVTASVHKLCVLVALHEEAA -AGRVDLTEQIEVPLEERELPTGVAAMLDPVRMSLRDAAYLMMAVSDNTAAELLLARV-GL -DAVNATTARLGLTHTYAVHTFRELLAALDPARTNRSTPRDMTRLLAAVWRDEACAPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -AAATLPPADAVIGTTARIAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0ADA2_9CHLR ---ALDRQLAGIRERFSGTLSLAASNLKTDEAV-TLDAGMLLPTASTIKVCILAEVFHQRE -EGRLRLDERIEMQARDQVGGSGVLWRLNSGLPTLYDLCMLMIIKSDNTATNMLTDRVGGV -GIINRRMRDYGLAETSYHSRVDF--EAIGNDVRAESTPYDLMRLMAMLARGEVVSPQASR -EMLAIMQRQQY-LDQFPRYLNSTMRVQNKTGFFP-GTGVDIGVVNLPEGVDIAYAVFAHA -SRDHTVA---------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Hydrotalea sandarakina TaxID=1004304 RepID=A0A2W7RQ57_9BACT --kKLTAELQSYLKKFHGQAGIYVYSFQQHKQV-AIAADTVFPTASMVKVPILIALMDKIK -AGELQYHQTFTYYDSLAYPGVDILASFKNGEIELSKLILLMLSLSDNTASLWLQAIAGGG -TRINNLMDSLGFTQTRVNSRTPGREAIRLQYGWGQTTPYEMAMILKRIASGTLLGQPYDD -KMLRLLSRNYW-DEEALSQIPANVFVASKNGAVD-ASRSEVLYVNGKKG-SYVFCLCTNH -NTETNNEAWALSRNISKLLWEYy ->[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. Root61 TaxID=1736570 RepID=UPI0009EAAA2C ---------------VPVRGLIHAVDIDTGHEI-GVGSDESVVSASVFKVPVLVELCRQYS -SGRIDPRARIALGADERRTGSTGISVMLDELLSVRDMSLLMMSVSDNRATDVITDLV-GL -DNVNATMREFGFDRTVVDYDCDMLFAATTPEETDRTTPRQIAELLSAIWRDELLDADAAA -EVRRVMGLQAW-GHRLTAGFSPAVRVSGKTGTLFY-VRNEVGVVEFPTGERFAVAVFLQE -PTPRNPDADRVIGTAARLAVDY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. ERV7 TaxID=1322334 RepID=UPI000B22942C -----LARIREAFDEAGVTGWLHALDIDSGAET-GVGGDHAVVTASVHKLCVLVALHEEAA -AGRVDLTEQIEVPLEERELPTGVAAMLDPVRMSLRDAAYLMMAVSDNTAAELLLARV-GL -DAVNATTARLGLTHTYAVHTFRELLAALDPARTNRSTPRDMTRLLAAVWRDEACAPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -AAATLPPADAVIGTTARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. TaxID=1831 RepID=A0A520FI07_RHOSO ---------------------------DDGGDI-AVGADDLVVLASVYKLPLLVSLCRAFD -SGSVSPTATVRVNPADCTPPTGVSKFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESIERMLSELGLTGTRVIGGTADAHRAYDPSYASATTPRDMTTLLDAIWTGSAVPEPQGE -FIRQVMAAQVW-QHRIRSGFPSDVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVSVFTRA -ARADLPVVDAAIGHAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia panacis TaxID=2340916 RepID=A0A3A4JXW9_9NOCA ----VPERLTEIFRAVGATGYVHAREVDGPGEI-GLGADHPVVLASVFKIPVVLTFARQVE -AGELDPTERTTITARDRIGGIGTAGCADDVEMSWRDLALFTLTMSDNAATDVLLRRV-GI -DAVRAVLAELGLERTRLIGGCEDLFAVCDPARTTASTPRELTTLLTAIWTDTAGPAEACA -RVRTIMGQQIW-PHRIASGFGDEVSIGAKTGTLPF-IRNEAGVITHRDGKCYAVAIFTVA -DSMRAPAVDAAMGKAARLVVD-- ->[subseq from] Beta-lactamase n=1 Tax=Lacrimispora sphenoides TaxID=29370 RepID=A0A381JN56_9FIRM ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEVFETASTIKTYILACLFDEVE -KGNKNLEDMIEYKEEHVVDGSGVLPDLEPGALRVKDAATIMIIVSDNIATNMMIDYL-GL -ERINQCIKALGCKDTVLHNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE -KMLDILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-5650 TaxID=1463868 RepID=UPI00068E0E3B ----------------------HAVDIDSGAQV-GTRAEQPVCTASVHKLCLLVTLHELAA -AGTLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLAAGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Putative beta-lactamase n=1 Tax=Synechococcus sp. (strain WH7805) TaxID=59931 RepID=A4CVR1_SYNPV ----LSDRWNQLAASEDLTVSAFMLVLDDGRYA-QLAPDTALPAASSIKTPILLVTLEEID -DDKLSWNEPLTLTKEVVGGGAGWMASPLGSRFPTHEVATEMIRVSDNTATNLLIDRLGGK -DALNARFIALGMSATVVNNWLPDLEGT------NTTSARDLARSIALVDTGKALSIRSRD -LFREVMGTSVT-NTLLPRGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Kushneria indalinina DSM 14324 TaxID=1122140 RepID=A0A3D9DXH3_9GAMM ------------------------------------------------------------- -----------------------------------------------------------GD -ERVAALARTLDVDREALNTDMTTAFDRYYDTRVNSATLKGYADLLTALVRGELINEEHRE -LLFDNLKIDRYDGYRLEGGLPQDVSFIQKTGTQHQ-RACHMGVIRPDEPNAIVIAACIED -MD-EGAPAEALFKQIGEAITE-- ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Cupriavidus TaxID=2640874 RepID=L2EKL5_9BURK ---RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA -QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELARLMIVLSDNLATNALIELL-GF -EGVNDWCNRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAASLCWLLRDGSLPAPLRD -FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG -FTDAGGDGAQWLAEAARIVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoflavifilum aggregans TaxID=454188 RepID=A0A2M9CVU9_9BACT --rKLQRKLEALVKPFQGTVGIYVHKLGTNREA-AINADSLFPTASMIKVAIQAVIFQRIA -DSQLQYHQNLLYRDSLYYPGVDILGMAKDSTIELSKVVMLMITESDNTAALWLQSLAGGG -TAINQWLADHGYQYYRVNSRTPGREAAYRQYGWGQTTPREMARFLVQLRKGEIISPAASE -RMYRNLCHIYW-DDVALSQIPPYVQAASKQGAVDD-SRSEVVLVNAPHGD-YVFCVDTKN -IATHSNAAWELIRQVSALLWHYf ->[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes TaxID=142182 RepID=A0A351FLB3_9BACT --eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE -SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM -GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA -RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY -GG----DGGAVIEAAQKAAYSYf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358IEP4_9BACT --eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE -SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM -GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA -RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY -GG----DGGAVIEAAQKAAYSYf ->[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D3QJL7_9BACT --eHLHSELSSIAERYEGVAGIHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE -SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM -GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA -RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY -GG----DGGAVIEAAQKAAYSYf ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00094032C5 ---AIADEIEAVFAKAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAQFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRQPAVDSSLGEAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7NZP1_9BACT ----LRLQIEKIVQGFAGKAWIAARNLGTGKSF-SLNSSERVRTASTIKLPILVALHAEVQ -AGRLRWEDCLTLAKKHRAQGAGVLMELEDGHLTLREASRLMVVVSDNSATNLVLEKI-GI -DTVNTWMDRFNLPKTRALAWIGGGAID--GSTHGVTTPAEMVDLLDRLNRGQIISPEDSA -QILALLGRQQY-KDGIGRNLR-GARVANKPGALDR-LRSDVGIITVGKE-KFALAITLDD -MP--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Hungatella hathewayi TaxID=154046 RepID=A0A413LQ89_9CLOT ----IEKRIEAELMSYDGTMGIYADDLH-GNII-AIGADEAFETASTIKTYILACLFDQVE -KGKASLEDMVEYKEEHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIRGLDCRDTVLYNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPESDA -KMLEIFKKQHY-NSMITKDFPAVVTVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNRK -F---------------------- ->[subseq from] serine hydrolase n=1 Tax=Xanthomonas citri TaxID=346 RepID=UPI001243DFB1 ----------ELVAHCEGRVGLVIETCEGR--I-EINHNDKFSAASLIKIPILIEGFRQYE -KGLLDLHEYLLALPSNRVGGAGVIQALSADLLKIIDLMALMIIVSDNSATNLVIDRV-GM -TEINECIKALNLQNTELNRKMMDFEAK-KNGLDNFTTANDMLTCLKVIDQHRFLSKESSD -KAFSILEKQQFKNKLAETIDSEAVQVANKTGELP-GVEHDCAIFKYGGK-TIYAAVLIDQ -LSRQEEGRLTLI-QIGK------ ->[subseq from] Uncharacterized protein n=2 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A3D2UF86_9BACT ---HLLSELSSIAERYEGVAGLHVLDLSSGDRF-AVRDELIFPQASAIKIPILLELFRRAE -SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNVLIDEL-GM -GAINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMQRIANCELMSEMACA -RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVNVPDR-PYVITVMSNY -GG----DGGAVIEAAQKAAYSYf ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. 48-14 TaxID=1895854 RepID=A0A1Q3WZU2_9BACT ---RLEQKLQSALAGFRGNAGVYVYHIRTGKRV-SINADTLFPTASMIKIPIQCGLFDKIH -KGELSYNQELVYKDSLHYDDGIVGSLKDGARITLSKVVMLMETISDNTGSLWCQALAGGG -TAINTWLETNGFHQTRVNSRTPGREANRGQYGWGQTTPRDMANLLLYIRQGKAVSPDASD -EMYRNLGRQFWDGDGL-SQLPPDVKVATKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN -QQERTNEGYALLRTVGSIVWHHf ->[subseq from] Beta-lactamase class A n=2 Tax=Alkaliphilus TaxID=114627 RepID=A0A1G5IV08_9CLOT --kELQDIIQKHINEIEGTAAIYVKDTETNEVI-TINSQERFHAASTIKIPILWEALRQVE -KGSIKLDDKILLKDVDKVGGCGVLFLHNGLQLTLEDLLHLMIDISDNTATNMVIDFI-GK -DNVNKALEELGMVDTFLARKLMVV---IPG-VYSYTCAKDIGRILEAFITHEGLHKEYAE -KGLAILEAQQL-NNRLSQEL---------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Deinococcus koreensis TaxID=2054903 RepID=UPI001056F6B4 ----------------GGRVAFCVHELGTGMIR-AQRADEVVPTASTYKLPLLLHIALLVE -EGALSWAQPFTLEDRHKSWGSGVLRDSVGLTFPLRDLCHLMTALSDNTATDLLLDTL-GL -DGVNRRLAGLGFEQTRLLPQHAAPGAGRPPLAVGVTTPAEMARLLRGIVLHELCSSASSS -VILGMLGAQHD-RSMIPRFLQPDWIYSGKTGSNED-LRADVGIVTDPQGRSFVLALYCQH -PT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Halorubrum aethiopicum TaxID=1758255 RepID=UPI0008303CBB ---DLAEAIDVIADRFDGRLGVLLGLSRGPDVLhRRNADEAFVAASTIKLPVLYALYEEYD -GRLDALAEPRPIAAENRVGGSGIFHLLDDPTPSLEDLARATIAISDNAATNQLIDEL-GA -ERIEAAASRLGMADTRLRRKMMATLEQPDGEPANVTTPADCARFFADIVHESTLSPAAYD -RLRVPLDEQKD-ASLFARYLPYGTPIAHKTGGLPT-AALDAGVVRADDGPPLVFTAFATQ -AEN-GGDAGDAVAAVGDAAFERf ->[subseq from] Beta-lactamase n=2 Tax=Rhodococcus opacus TaxID=37919 RepID=K8XS33_RHOOP --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGSQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Rhodospirillaceae bacterium SYSU D60006 TaxID=2268029 RepID=UPI000E65750B --dTLTARINEVAEEAGVFAFAHARDIDTGVEV-GFNSDAPTVTASVFKVPVLVEYVRQVA -AGELDPAKRIRVSPAEATLGPTGLSVFSDDAWSLRDIATSMITVSDNAATDIVTGLV-TV -DRVNATMRELGLPGTQLTGDCALIFEAATPEKTNRTTPREAASLLQQIWTDAAAPAEACA -EARRILGLQVW-PHRLSSGFPDDVKISGKTGTIGM-VRNEIGVVEFPGGKRHAIAVFLRG -KTSRNPAADRAIGDIARLLSD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Synechococcus sp. Ace-Pa TaxID=2572902 RepID=A0A560LMM5_9SYNE ----LSQRWKALAAQKDLKAGAFLLVLDDGRFA-QLDSELPLPAASSIKTPILLAGLEDLD -AGKLRWNEPLPLTKEVVGGGAGWMASRPGTRFPFYEAATEMIRVSDNSATNLLIKRLGGK -LALNARFQALGLGATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGEKLSPRGRD -HFRTIMGTSRT-NTLLPLGLLEGVTVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG -PFND-PRSADLIRAMAAAAS--- ->[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus massiliensis TaxID=1462526 RepID=A0A024Q8C3_9BACI --------------------KYFSIYIETPDGIiAINEDKQMTAASLVKLPILLEGFRQLE -NNHLLEDKLVYIDKDEMVGGAGVINYVSKSHYSYKNLMELMIIVSDNTAANLLLKLF-GM -AAINQFIKSIDCEQTLISRKFMDVEAS-ENGKENYTSAKDMIKLFKLVSKNHHLTDSSRR -MILKILENQQF-THKLPSYLDKSIRFFHKTGEMP-GVSHDAGIIKYETK-TIHVAILSEG -VA-HNTVSERIIADIGHLLS--- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429C8Q1_9PSEU ---TISDEIEAVFAKAGARGFVHAREIGDGPEV-DVGADDPVVLASVFKIPVAVAFAREVA -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPADVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -GSDRLPAVDSAIGEAARLAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Subdoligranulum sp. 4_3_54A2FAA TaxID=665956 RepID=G9RYL9_9FIRM --qELCAALDAQLAAAQEQVCVLAVPLAGGVPLyERGAGRRAVSASTIKVFILLAALDEVR -RGRLALDTPVAVAAEDILPDTGVFVDGP--GHPLEELLVWMIVLSDNTATNVLIGLL-GA -ECINAAACSVGTKNTVLERKMLDWDA-VSAGRNNYTSAEDLLRVFRALYDETVLTPELCA -LARSILRRQRD-TRMLTRYIWQDVPCAHKTGGLDR-LSHDAGVFELPGR-PYFIAVLIWD -AP-DIDGDEPLAGRVSKLVFDYy ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A402CDX0_9NOCA ----------------------------DAGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERVLSDLGLTDTRIIGGTADTHRAYDPSYASATTPREMTSLLDAIWTGRAVPGAQGE -FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA -ARTDLPVVDAAIGHVARIAVT-- ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Shapirobacteria TaxID=1752721 RepID=A0A2M8L7Z1_9BACT ------DQIKAVTTPLLGVYGVYVENLVSGHQY-GLFQKQTFPMASLVKLPVILTLYQEAE -ADRLNLEDEYPLREADKLGGAGILQSQPAGSYTYRQLAQLMGHYSDNTAYNVALKVL-GL -AKVQRTIEQLGMASTALADFE--------------TTPADMGLFFRRLYAGKLVNNLHQQ -EIFEFLTATVF-EDRIPAGVPEGVRVVHKVGTEI-GNFADAGIVMAP--QPFVLVIITQD -ARES--EALTALPEISRLVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Niastella vici TaxID=1703345 RepID=A0A1V9GA25_9BACT --hRLQKQLSDLVKDLHGDIGVYVKNLRTGKSA-MVNADSIFPTASMVKVTILIGIQDKIE -KGQLEYHQPLEYKDSLFYAGEDILGSFKNGEIGLNKVMMLMLTTSDNTASLWLQSLAGTG -TRINEILDSLGLVHTRVNSRTPGREANRQQYGWAQTTPREMGTLMEKIYRGEVISKSSSE -KMIRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPHG-PYIFSVQTKN -LQGNSNEAWVLTRKLSALCWNYf ->[subseq from] serine hydrolase n=1 Tax=Flavihumibacter sp. ZG627 TaxID=1463156 RepID=UPI00069388A4 --rKLQKAIESLVEGFKGTVGIYVKHLPSGRSA-QINADTLFPTASMVKIPIMIGIMDKIH -KNELQYHQPLVYNDSLLYAGEDILGSFKSGEIQLAKVLMLMMTTSDNTASLWLQSMAGTG -TRINQLLDSMGYSATRVNSRTEGRRGHWEQYGWGQTSPREMVRLLEQIYQRKMINDTLSE -RMLRLMGRNYW-DEEAISMIPPEIFVASKNGAVD-ASRSITMLVMAPHG-PYLFSVITKN -QPDT------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1I0X2P5_SELRU ----------QVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH -DGRLSLEEQLTIRKQDVVGGAGVTTWYNTGERTVAQLIQLMVVESDNTATNMLIDKL-GM -ANINQYLQQYGYKDTMLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA -FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS -SE--------------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Marseille-P299 TaxID=1805477 RepID=UPI000835E499 ----LLDRIKAEILSYDGLMGIYINDF-KGTKI-EINVDEEFETASTVKSYILACLYDEVQ -KGNKSLDDMLTYTSDNFIDGSGILRSDLGVTMTVKNIATLMIIVSDNIATNMIIDYL-GI -DTINTFMKNQGFSSTVLHNKLD-FEK---YDKLGTTTPRDYATLFERLCNEELVSKEASR -EMLEIFKKQHY-NSMLTKRFPQAIYVASKSGSMN-ACRNDGGIVSTPYGK-YVIVLMNKN -FHDPEHSATEFGSKVSRLIFDQy ->[subseq from] serine hydrolase n=1 Tax=Komagataeibacter pomaceti TaxID=2021998 RepID=UPI000D7BDDCF ---TLSDDIAKTIQGQPGHFAVYAAMSGQPPQV-CLNCDDFIDAASTMKLFVMDAAYDSFT -KGTLYPQDMIVVHNRSLVGGSFALYAAIGRPVAVSELLRVMIQYSSNLATNLMIERI-GV -PYVRAIVAAQHLDGIRFGRMIEDYDAN-SQGIHNQVSARGLGLFLQKLDHGDIVGPAQSQ -AMIDIMKGQKF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNTISRQVHDSf ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis benzoatilytica TaxID=346045 RepID=UPI0003810588 ----VQEQIEAVFADADTDGFLHAREIGDGPEV-SVNGDDPVVLASVFKIPLAVAYAREVV -AGRLDETERTKVTARYRTGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRV-GQ -DAVDRVLADLGLSRTRLIGCCEDLFAVRDPERTTSSTPREMTALLDAIWTDRAADPAACE -RVRTIMAQQIW-PHRLSSGFPSGVAVAAKTGTLP-GVRNEAGVVTLGDGRQFAVAVFTRA -HSDRLPAVDGSIGAAARLALDH- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter xinganensis TaxID=1234841 RepID=A0A223P0W5_9SPHI ---RLTIKLQEAVKGFNGQIGVYVHNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE -KGEMQYNQKLVYHDSLLYPGEDILGSFKDKDIEVSKVAMLMITMSDNTASVWLQKLV-GG -EYINNWLEKNGFKVMRVNSRVPGREAIRAKYGWGVTTPYEMCRLFTLIRKGEAVSAGASE -RMYRNMGRIYW-DDKAISQIPPFIETASKQGALDE-SKSETVLVNAPHGD-YVFSIITNH -NKKPDNEASVLIKKISALLWHYf ->[subseq from] Beta lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=E0D3F8_RHOOP --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. E2N166 TaxID=1851909 RepID=UPI000EF67662 ------GRLQAAFADAGVTGWLHAVDIDSGAQV-ETGADQAVCTASVHKVCVLVTLHELAA -AGALDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTDRLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLTALWRDEACPPEYGA -AARRVMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEIGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428XKT8_9PSEU ------AEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTPREITTLLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA -ESDRLPAVDSAIGEAARLAVAH- ->[subseq from] serine hydrolase n=1 Tax=Streptosporangium amethystogenes TaxID=2002 RepID=UPI00068D4EE3 ----VSKSIQKLFADASCDGWLCVLDIDGTAEV-HVGGDDLVVAASVFKVAIAVEVFRQAD -AGHFDLQDRVRIRPNARTVGPTGFSTFADEVASIRDLTRMMLVVSDNAATDILIDRV-GL -DRVRATLTELGLKVTAIPFSLQGMLDAMQPEHAIRTTAREMARLLRLIWRDEAGPAEACA -QVRHLMAQQVT-KNRLAMGFQRDVRVAAKSGSLFGVIRNEIGVLERTDGRRYAAAVFTRA -HRINENEINTVIGTAAALAID-- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012FCE60C ---------REIFDAAGVRGFVHARDVDDPAEV-GLDAGAPVVLASVFKIPIVLEYARQAA -KGELERTERLTVTAADKDGGIGTSGLADDVSLTLRDLAHLTLTLSDNAATDVLLRRV-GL -DRVHATLAELGLPRTRLIGGCAELFDVRDPERTTSSTPREITALLSLIWRDEAGPAEACA -EVRRIMGQQVW-PHRLTAGFDESVKVSGKTGTLW-GVRNEAGVVEYPDGRRYAVAVFLRT -TKLRDPAADAAIGRAARVAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus paucivorans TaxID=616990 RepID=A0A0R2LWJ6_9LACO ---EIKDAVTAALDPLQGTSSAYVSPVDSSQSV-VV-NNGSQSAASSIKVFILVTAYAMAK -EGVFDLDATHTVTDSEKVGGTGVIQDMDAGTLTYREVLQHMIDDSDNTGANIMIAKMGGF -SLINNKIKSMGATDTKLQRKMMDTD-AIEDGRDNTTSARDLGMTLKKIYNHQLVSKTADD -DMLEILANNRN-RAKLPKLLPSEAKVYNKTGEYDYGVQNDAEIVANKRGA-FVAVVLAQD -GK-EADQ---------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 142MFCol3.1 TaxID=1172179 RepID=UPI00099671E4 ---QVRRTVAEAFAAAGSGGFVHAVDIDNGVQF-EYGADTPVVLASVCKIPVLVELYARSD -EGTVDLSGRVHVQATGRSPGPTGLSVMLDPAVSLRDLAYWMMSVSDNAATDVLCELL-GL -DAVNARMSGLGLKEVRLEGTCRDIYDQIPTAT--RGTPRSITTLLSMIWRDQAASPEACA -AMRRILGLQVW-PHRLRSGFPDRVAVAGKTGTLPF-VRNEVGVVEYPDGGRYAVAVFTCP -DSYANPPADAVIGTVARAAVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=B5B4Y9_ACIBA ---------------------------------------EKFPMQSVFKLHLAMLVLHQVD -QGKLDLNQTVIVNRAKVLQWAPIMKAYQGDQVPVQQLLQYSVSHSDNVACDLLFELVGGP -AALHDYIQSMGIKETAVVANEAQMHADDQVQYQNWTSMKGAAEILKKFEQKTQPSETSPA -LLWKWMVESSTGPERFKGLLPFGTE----------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C882D3 --qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPASERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSADDATASLCWMLRDGALPAALRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Peptidoglycan-binding protein n=2 Tax=Bacteria TaxID=2 RepID=K2C2M3_9BACT ----IEQKVRNYIKDKPGNYGIYFEDLNSGQNF-SINGKEIFTVGSINKVPIIAVLYYLDN -KGEISLDSKVTIQKKDIQDGTSLRYAKPGGNYSLKNLARLSLVQSDNTAAHIIGVKI-GT -DKIQKIINSWGLTQTDMT--------------NNKTSAFDMSIIFKKIYKGEITNNAKTQ -ELLEFLTKSDF-EDRLPVLLPKQTTVYHKTGDAE-GIVSDVGIIKNEHK-LYYLGILTTD -VADKENLTKKTISEISEMVYKY- ->[subseq from] Uncharacterized protein n=2 Tax=Komagataeibacter maltaceti TaxID=1203393 RepID=A0A2S3W282_9PROT ---TLAQDVAKTVAGQPGHFAVYAAMSGQRPQV-CLNCRDYINAASTMKLFVMDAAYDMFT -KGTLHPEETIVVHNSSLVGTRSFAYAQIGRPVAVSELVRVMIQYSSNLATNLMIERI-GV -PYIHAVMDAQHLRGVRFGRMIEDYDAN-DRGIHNEMTARGLGQFMQKLDHGEIIGPAQSA -AMIDILRGQHF-NDMIPPGLPSGTPVAHKTGWVE-GVRNDAGIVFLPDGRHYILVMLTKS -LP-DEAAGIRVLNTISHQVYDHf ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. USBA 49 TaxID=1881060 RepID=A0A1T4X2I5_9CLOT ------KELKRYLDQRIGEYSFYFEDINSSYTY-SFNERIKMPSADCIKIHIAIALLKKVQ -DNFIDLYENVLIKKEDMVSGDGIIHEFDEKEYKIIELLNAMLIQNDNTAANKIIDII-GM -ESINEVIKEMGLKDTVLKRKMMDFKSH-EKGLENLTTSLDLANSLKLIYQGKYLNEEYSS -IILNSLRKSQD-RRKIPFYIPKEWKIGNKTGSLH-GVENDAAILNTKKGD-FIFVVMAKT -LP-NNVYGIVTISRLGKMMW--- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A6B1FIH3_9GAMM ---KLQGELEGIVDGYEGVAGVHIIDLTSGDRF-RVNDELVFPQASSIKIPILLELFRRAE -EEPGLLRRRIDMTDEVRTGGSGVLLHLTDGGLSLEDYAIYMIVYSDNTGTNVLIDEM-GM -DEVNALSASLGAEHTLLQRKMIQPEES-ARGNENLSTPRDAALIMERIANCDLMSEASCA -RVREILEIFKGG--PIRNPVPRNVPIAFKPGGIT-GVSTVWGLVDVPDR-PYVISVMSNY -GG----DGGTVVEAVSAAAYDYf ->[subseq from] Possible beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain CC9902) TaxID=316279 RepID=Q3AYZ4_SYNS9 -------WIQQAATQPDLQVSAYMLILDDGRFA-QMHANRPMPAASSIKTPILLAVLERID -QGTLQWNEPLTLTKELVGGGAGWMASRPGTRFPTYEVATEMIRVSDNSATNLMIARAGGQ -DAINARFQALDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGESLAPRSRD -LFREVMATSVT-NTLLPTGLMRGYRVFNKTGDIGT-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTEMIRQLAAAMA--- ->[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4QM72_9FIRM ------SELTALAAGFSGTIGVWARSLDTGEVIrAGACDDPFPSASTIKLAIFYELMRQAG -EGKLDLDEARTLRAEDKVPGCGVLRDLTPGILPLRDLATLMMTISDNTASNMCIDAV-GI -DSVNRSMDALGLPGLRLRWKFF---CAPEGQPVNSAVPSQLGRLMDMIVRHEVLTPAACD -EMLRVMKRVQSAARYLPGGAPAGPVIAAKFGSIT-GCRHEVGAVWKGGR-GFVFSVMTKD -CKDERPEDNEGVLAVGRAVA--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=UPI0009ED4191 ----LEYKIREIMVRSIGSVSVAVEL--PYHSF-HIDGDRSYSAASLIKIPILLEAFRQAQ -EGDIFLSDMVTIPKEGRVGGAGVLVSLSDQLLTIEDLVTLMIIVSDNTATNFLIDRL-GS -NAIQELCHSLKLKHTRFLRKMMDFE-ALEQGVNNYTSALDIITCLKVLDIGKEYCQTSRG -KMLHILGQQQF-DTKLPSRMDEAVYIGNKTGELP-GVEHDCAIIKYREKT-AYIAVLIDG -LGET-ESGKDTIAQIGKLIYD-- ->[subseq from] Serine hydrolase n=2 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A511FM00_9PROT ----LAQTVARMVESQKGHFAIYAALSGQAPVV-CLNCDDLINAASTIKLFVLDAAYDAFA -KGTLRPDETITVHNRSLVGTGNFAYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -MPIRSVVKTQGLNSIVFGRMIEDFDAN-DQGIRNEVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGRHYILVVLTSG -LP-DEQAGIKVLNTLSSQTYAYf ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E9TI12_9BACT ---------------------------DDGKSI-LINENEVFHAASTMKTPVMIEFFKKIN -EGKISSDDSLLINNESIVDGSKFEYKNLGKYISTDKLVYDMITRSSNFGTNLLIDYL-DA -EDVNNTMKNIGAKNMKVLRGVGDLKA-FDLGLSNTTTAADLLIIYEKLAMGKIVNNESSN -KMIRILKDQVY-NDIIPKYLPEKVEVAHKTGWIS-GVRHDSGIVYVGNNEKYILVLLSKN -LE-DDIEGADFLAKISLEIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A5Q4DAB7_9BACT ---QFQATLEGLVAGYEGVAGVHVVDLTDGTSF-AVRDDFVFPQASAIKVPILIELFRRAE -SEPGLLSRRVEMTDAVRTGGSGVLRYLTDGGLSLEDHAVYMILYSDNTATNVLIDAL-GM -EAVNALSASLGAPETLLQRKMIRPEES-ARGNENLSTPRDAARIMERVADCALMTEASCV -RVQEILGIPKD--GAFVDPIPSDVPVAWKPGGIT-GVATAWGAVNLPDR-PYVLVVMSSF -GG----DGGALIREVSEAAWRYf ->[subseq from] Uncharacterized protein n=1 Tax=Haloprofundus marisrubri TaxID=1514971 RepID=A0A0W1RCN0_9EURY --nALQARVDEYANKTDGRLGVFVIPTENGDTIaSHSSEAVFASASLIKLPILYALFDEYW -DSKSRLAQEVGLSDTNMVAGSGLLHLLSEHPYTLDDLARAMIAISDNAATNQLIDTL-GM -ERIERAVSDLGMSETRLGRKMMTTGGNLEESPVNTTSPRDAARFYRNVVRRESLSVPAYE -SLEVPLYAQKD-ASMAARYLPYDVELGHKTGWLTH-AALDAGVLHCRDGEPIVFALFVDR -LA-YAGDGTDIIAELGLAI---- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI0013916AAF ------------------------------GEV-DINAGNPVILASVFKIPFVVAYAREVA -AGRLDPEERTTVTARDRIGGVGTAGCADDVEMSWRDLATFMMTMSDNAATDIIYRRV-GQ -ERIQAVLDDLGLTGTRIVGCCADLFAILDPSRTSATTPRDTTTLLAAIWTGAAAPEAACA -DVRSIMAQQIW-PHRLSSGFPDEVDVAGKTGTLP-GVRNEAGVVSYPDGQKYAVAVFTRT -DVLDLPQVDAAIGTAARLAVEH- ->[subseq from] serine hydrolase n=1 Tax=Heliobacterium undosum TaxID=121734 RepID=UPI001370B561 --dKLRQRIRKDMAESGVDYALFLEDLKSGRQF-TIEPDKNFQAASAIKVPLVLFLYALAL -DKRIDLDETMTLTSGDLAPSSGGLWSRPGRQYTLRQLAKHVIEDSDNTATNMLMRRV-GR -SNFYLFLRLAGAHTVPAG----------PG-KGNVTCARDMALYLKGIWIFRQLNPDYGE -EMFQYLLHSKI-DDRIPAGVPDHIKVANKIGSQI-GFFHDAAIVMLPNR-PYVLAILCHH -PSE--TEANAAIARISRIIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SynAce01 TaxID=1916956 RepID=A0A1J0P8C4_9SYNE ----LSQRWKALAAQKDLKAGAFLLVLDDGRFA-QLDSELPLPAASSIKTPILLAGLEDLD -AGKLRWNEPLPLTKEVVGGGAGWMASRPGTRFPFYEAATEMIRVSDNSATNLLIKRLGGK -LALNARFQALGLGATVVNNWLPDLEGT------NTTSPHDLARSIALVDTGEKLSPRGRD -HFRTIMGTSRT-NTLLPLGLLEGVTVLNKTGDIGI-AYSDAGLIELPNGQRAVAAFMVKG -PFND-PRSADLIRAMAAAAS--- ->[subseq from] Beta-lactamase class A n=2 Tax=Actinomadura hallensis TaxID=337895 RepID=A0A543IAD5_9ACTN ----VTERIEEEFRSAGVTGWLHVVDMDSGREV-AVRADEPVVLASVFKVPLLVAFHRLAA -EGRLDPAEQVALPPRERTAPTGISGMRDEVRMSLRDLTFLMITVSDNAAADAVLDRV-GR -DAVNATAAALGLRDTVVEVSGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPGECG -EMRRLFGLQVW-PHRLASGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS -PLAVLPQADAVIGTAARLAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075UTX6_9PSEU ---AIADEIEAVFAKAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRQPAVDSSLGEAARLAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8QTB0_9BACT --eHLHSELSSIAERYEGVAGMHVLDLSSGDRF-AVRDDFIFPQASAIKIPILLELFRRAE -SDPGLLSKRIEMTEEVRTGGSGVLGVLTDGGLSLEDYAIYMILHSDNTATNILIDEL-GM -GPINALSASLGAPNTLLQRKMIQPEES-ARGNENLSTPRDAAEIMKRIANCELMSEIACA -RVIEILSIPKGG--PIRRPVPNAIPIAFKPGGIT-GVATVWAIVDVPDR-PYVITVMSNY -GG----DGGAVIEAAQKAAYSYf ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus sp. 7884-1 TaxID=2021693 RepID=A0A268K749_9BACI ----LKEKIREELYGFDGRIGLAIEI-EDAGNF-YIDSEEVFRSASLIKIPILLAGLGRHK -IGELDVEQLIPISKENRAGGSGILYALSDQLLTVKDLMTLMIIVSDNTATNILIDLL-GM -DKINAFIKEIGFEHTKLNRKMMDFA-AIEKGIDNFTNSREMIHSLKLLNENDVIGITGPP -IAYHALRHQQF-RDKLPAMVNEKITVVNKTGELPS-VEHDCAIFEYQGRK-GYIAVLTDS -VI-DQNEAKQIIRNIGKHISDFf ->[subseq from] Beta-lactamase class A n=1 Tax=[Clostridium] celerecrescens 18A TaxID=1286362 RepID=A0A2M8ZC64_9FIRM ---TLEKRIEAEIMSYDGKIGIYLDDF-HGNVI-AIHADEAFETASTIKTYILACLFDEVE -KGNKSLEDMIEYKEEHVVDGSGVLPALEPGALRVKDAATLMIIVSDNIATNMMIDYL-GL -ERINQCIKALGCKDTALYNPIHF-E---QYDRLGTSTPEDYASIFIRLAKGELISPGADE -KMLDIFKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] Uncharacterized protein n=1 Tax=Halorubrum halodurans TaxID=1383851 RepID=A0A256IJM9_9EURY ---DLAEAIDAIADRFDGRLGVFLREVEEFDVLhRRNADGTFVAASTIKLPILYALYEAYD -GRLDALAEPRPIAAENRVGGSGIFHLLDDPTPSLEDLARATIAISDNAATNQLIDEL-GA -ERIEAAAARLGMADTRLRRKMMATLEQPDGEPANLTTPADCARFFADVVHEATLSPAAYD -RLRVPLDEQKD-ASLFARYLPYGTPIAHKTGGLPT-AALDTGVVSADDGPPLVFAAFATQ -AENG-GDAGDAVAAVGDAAFERf ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma montaniterrae TaxID=1178516 RepID=A0A1P9WRH0_9BACT ---NLDLQLKDALAGFRGDAGVYVRNLRTGETV-AINADTLFPTASTIKVPIMCGLFDKIH -KGELKYGQELVYKDS-LHYDDGITGQLRDGAIPLSEVVMLMETVSDNTASLWCQALAGGG -TAINAWLDANGFPKTRVNSRTPGREAFRSRYGWGQTTPRELAELMVYIRQGRAISPDASE -EMYRNLGRQYW-DNDALSQIPPDIKVATKNGAVNR-SRSEVVLVHAPHGE-YVFCLMTKN -QQERANEGFTLLRTVSALLWRHf ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. cl95 TaxID=1761761 RepID=A0A1I6BTT8_9BACI --nQLQVELLEIVNNCPGRASLSIDICGTSWEL---GGREVYKSASLIKVIILIEALRQVE -QGIYSLNDKFVITNDSKVGGAGVIQALSDSIFTYSDLLTLMIIISDNTATNQVIELL-GF -DSINRCCKDLGLVDTALNRKMMDFGAA-QQGRENVTTSGDMVSCLKKVNEESFLSEVGRA -EFLRIMSLQQF-QNKLPARIDEKVKVANKTGELP-GVSHDCALIEFDGKI-AYVAVLIDE -LVVT------------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. SYSU GA17076 TaxID=2700083 RepID=UPI0013D31F6B -------DIKKFLDSRIGDYSFYFEDLSSGYVY-AINENVRMPAAGSMKLPIAIALFKEMQ -LGKIDINMKVKVKTEDMVYSTGILHEFSERDYSVKELLTAMLLHSDNTAANKLIDII-GM -DRINEIIRDMRLANTVLNRKSIDERES-HSEIQNYTSAMDLSKCWRILYNGIFVDKENSR -IIIDILKRQQL-KNKLSYYYPERIKIANKTGDIDN-VENDTALMSINKG-SFIITVMSSN -LPN-NVYGQITLARVGKMALD-- ->[subseq from] Serine hydrolase n=2 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1W2LT78_9PSEU ---AIADEIEAVFAEAGARGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVV -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRQPAVDSALGEAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. WB9 TaxID=2594007 RepID=A0A516WPH1_9NOCA ---------------------------GDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] metallo-hydrolase family protein n=1 Tax=Pseudoclavibacter sp. CFCC 13796 TaxID=2615179 RepID=UPI0013010BF0 ------------AEAQHVKVGVTVQDLSGDAVLtAGAHDAPFKAASTIKLGLTASLMHQID -QGKLSLDTPITIQQSDLVGGSGTIQNDPTILFTLSQLIELMITVSDNTATNRLIDVAGGF -DAVNAYTQSIGLQGFHLGRKMILPHTA---EQENWISSDEDAKLLTKIYQAAIISQQSAQ -QVIAWMRAQKV-NTKFGAVVPRE-VLANKTGENTD-VSHDTGYILVPGK-EVAISVMTSF -DPTAFDTANTQVQQVAKAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A3D3CQX4_9BACT --kELQKKIENLLNGFHGTAGIYVHDLKKNRIV-SYQADTLFPTASVVKIPIMIGIMSKIQ -HKELDFHQWIVYKDTLNYDGEDVLASFKPDQIMVSKLMLLSISLSDNTASLLLQGLAGGG -QRINELMDSLGYVYTRVNSRTPGREKDREIFGWGQTTPREIALIMEQIVEGKVLGRRSSD -RMLRTLGRQYW-DEDAISQIPPNVFVASKSGALDE-CRNEILYVNAP--HPYIFSIFTKN -NTDQWDY---------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI0007083B8C -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS------------------- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. Z-333 TaxID=2614799 RepID=A0A5J5JQ56_9MICO -------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE -AGMLTLDDIRTILPEERYEGSGILKDGPFPQVSVGRMLDLVITVSDNTATNKLVDVVGGF -GPINATIESAGIARTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYESSFLSSASAE -HIIDLMLAQQV-KTKLGATVPAG-ILAHKTGENAE-VSHDVGMVLLPGQ-EITLSVFSTV -RPDVQATANPFLQRIGTVVHDY- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q3W9Z6_9BACT --kKLESMLQNAITGFNGDVGIYVKNIRTGKIV-SINADTVFPTASIVKVSILLGVMDKIR -NGELHYDSTHVYKDSLLYAGEDILGSFRDGEIALKKIMMLMLTTSDNTASLWLQKLAGTG -TRINALLDSLGFLHTRINSRTPGREEIRKVYGWGQTSPSEMGRLFEMIYQSKVFSPAYSE -RMMRVLGRNFWDEDEAIAMIPPYIEVFSKNGCVD-ASRSEAMIVNAPNN-PYVFCIFTKN -NKKHTNEAWTLARKISTLLWEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma fluviale TaxID=1597977 RepID=A0A286GQT8_9BACT ---ALERKLQAALSGFQGDAGVYVHNLKTGKTV-AINADTLFPTASTIKIPIQCGLFDKIH -KGELTYGQTLIYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG -TDINSWLEANGFHQTRVNSRTPGRKADQTRYGWGQTTPREMAELMTYIRQGRAVSADASE -EMYRNLGRQYWD-NDGLSQVPPEVKTACKNGAVNQ-SRSEVVLVHAPHGE-YVYCVMTKN -QKERSNEGFALLRNVAALLWQHf ->[subseq from] serine hydrolase n=1 Tax=Kitasatospora sp. MY 5-36 TaxID=1678027 RepID=UPI0009EA7395 ---AARTRIAAAFADAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA -AGRIDLTRQVDVPAAGRTPGSTGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL -DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGT -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATTLPAADAAIGTAARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OK268 TaxID=1881048 RepID=A0A1H0X566_9SPHI --rKLTQQLNDAVKGFHGQVGIYVQNLKTGKTA-SINADTLFPTASMIKVSIQCGLMDKIE -KGELQYNQKLVYRDSLLYKGEDILGSFKDKDIQLSKVALLMITMSDNTASTWLQKLV-GG -DYINNWLQQNGFKVMRVNSRVPGREAIRSIYGWGVSTPFEMCRLFTMIRQGKAVSPAASE -RMSRNMARIYW-DEKALSQIPPYVQTISKQGAVD-AAKSETVLVSAPHGD-YVFSIMTNH -NTDQDNEASVLIKKISALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Achromobacter dolens TaxID=1287738 RepID=UPI0011A28699 --qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA -KGRYALEQPLALPASERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNT372 TaxID=1169154 RepID=UPI00036773D9 ---QVHTVLASTFDQAGVEGHVHARDLGTGEEF-GHGADSQVVLASVFKIPIALEYARQAA -AGELDPAGRHTVTAAYRAGGSGTDGCAYDVEMSARDLAFMMMTISDNAATDLLLDVV-GP -DRVRATLDGLGFPGFGFSSSAA-LDDACAPGSSPSSTPREVTALLAAIWRDEAGPASACA -EVRDIMSQQVW-QHRLVSGFPAGVRLAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT -STAAQPLADRAIGRAARIAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OV119 TaxID=2135470 RepID=A0A318UJ23_9SPHI --sKLTAKLNDAVKDFHGQVGIYVHNLKTGKTV-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQRLV-GS -EYINNWLDQNGFKVMRVNSRAPGREAMRRIYGWGVSTPREMCRLFIMIREGKAVSPAASE -RMYRNMGRIYW-DDHALSQIPPYVHTISKQGAVDD-SRSETVLVNAPHGD-YVFSIITNH -NKTPNNEAGLLIKKVSALLWNYf ->[subseq from] serine hydrolase n=1 Tax=Emticicia sp. CRIBPO TaxID=2683258 RepID=UPI00141313FD ---KLQRLLENTLKGFNGDAGVYVHHLKSGKFA-AINADTTFPTASLIKVPIMAGVFDAIR -NNKLSYKQDLVYRDSIKYDNGVVGSLKDSTVISVSKVIMLMETISDNTASLWLQGIV-GG -TRINELMDSLGLQKTRVNSRTKGREAFRSVYGWGQTTPREMATLMEKIRLGQLYSPDASD -KMYRILGRQFFEEEGL-SQIPASIKTASKTGAVNQ-SRSEVTFVHAPHGE-YVYCIITKN -QKDASNEGYELIRKVSSVLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P1ZW70_STRVZ ---QIHTTLASAFAQARAEGFLHVRDLDTGGEF-GHGADSQVVLASVFKIPIALEYARQVA -AGELDPARRHTVTSAYRAGGSGTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIL-GP -DRVRATLDELGFPDFGFSSC-AALDDACAPGTSPSSTPREVTALLAAIWRDEAGPTSACA -EVRDIMSQQVW-QHRLVSGFPPGVRLAGKTGTDFP-VRNEAGVIEYPDGKRYAVGVFLRT -STNRQPLADRAIGRAARAAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. AF28-13AC TaxID=2292234 RepID=A0A3R6LYL0_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGRTV-EIGADEAFETASTIKAFILAALYLQVS -RGKASLDERITYEESQFVDGSGMLRAGVGAALKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLH-FDR---YRDLGTTTPRDYAALFAQVAKGTLVSREASA -EMLAIFRQQHY-NTMLTHDFPERIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] serine hydrolase n=2 Tax=Apibacter sp. HY039 TaxID=2501476 RepID=UPI000FEB743B ---EFNDSIYHLIKNKKLDIGISVRDNTGDEIV-SYNQNKKYKLYSVSKYFLGLYILDQVD -KGNLNLNQPVIFSKKDLKPYSPLRDSNPGTTLTLKESIKYLIEDSDNNVFDKLIDISGGF -QRLNLFVHQIVPNKFAINAGYSDSETL---FQSNVITPSLTTEILYKMENRQIISDESLN -LLKFYMQHSVN-NKRIQGLLQTKTKSFHKSGTSGRKATNDIGIVELQDEQSFSIAVFISN -SHEDDATNEYIIAKLADIIYD-- ->[subseq from] serine hydrolase n=1 Tax=Sphingobacterium psychroaquaticum TaxID=561061 RepID=UPI00106CD49C --kKLEERLKKETENFQGDIGIYVQHFKKNTTV-NILADTIFPTASIVKVPILVGIFNKIN -EGSLTLRQPFRYDAKRVYGGSGLMQFYKDSATELSIMISLMLTYSDNVTSIWNQELAGGG -VEINRIMDQLGLVNTKVNSRTTGREQLWRKYGWGQTTPKEIASLMHLIRSGKVFNPQLSD -KMYRYLKNQFY-NERSLSQIPAEIATASKTGSVDD-ARGEVVYVHAPSGD-YVFSVLTKN -NKTDENEAEKITRKIASIIWNYy ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2ABK7_9BACT ---ALKKQIQEVVRQQTGSYSVYFSNVDDGRLSfGINENFIHTAASVNKVPIVVTLYYLAS -QNKINLDEKITVQENDIQDTGSLRYEEPGRSYSLKTLAKLTLEQSDNTAAHILAQKI-GT -DNIHEVIENFGLTQTSMEN--------------NKTTLTDMHILFKKIYSGEIANKALTN -ELLDFLKDTDI-EDRIPKLLPEDTVVYHKTGDAV-GIIHDVGIVEQSNNA-FFVGIMTSD -IGNREEETKNAIAKIAKIIFD-- ->[subseq from] Serine hydrolase n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A5N7YUH8_9BURK --qHLDATLTPLLAATPARVSLSLRDLDGGVVL-AHHAERAQPAASIIKVPILLTLLAAVA -EGRYTLEQPLALPAADRAGGTGILAQLPGVTLSLAELARLMIVLSDNVATNALIDLL-GF -DAVNQWNPAAGLTASRLQRRMMDAAA-REAGRDNFTSAGDATAALCWLLRDGALPAPLRA -FALDVLADQRE-RAHFGAALPAAAHLASKAGQLP-GLRHDAGILTVDDC-SVVLAVLADG -FT-DWQTAHTLHGGAGAA----- ->[subseq from] serine hydrolase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI0009FD5742 -------SVQEIFRTAGVEGWVHTQCVDCGAQA-GTRADEPVVLASVVKVPLVLEFARQVV -AGQLDPADRVRARAADRLGGVGTAGCTDDVELSLRDAAYFALTVSDNTAADLLFDRV-GL -DNVRSLLRELGLTATRVVGPPRAVVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR -WVRDLMRQQVN-WYRLAAAFPPEVGVWAKTGTLP-GVRNEIGVVEYPDRKRYAVAIFTRA -ATQRLPEVDRAIGAAA------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. AcE210 TaxID=2292703 RepID=A0A371XP13_9ACTN ---AIADEIAAVFAEAGAQGFLHAREVGDGPEV-AVGADAPVVLASVFKIPVAVAYVREVA -AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVFHRV-GQ -DAVDRVLTDLGLSRTRIRGCCEDLFAVLDPDRTTSSTPREITRLLDAIWTDRAADPGACE -KVRAIMGRQIW-PHRISSGLDTGVQVAAKTGTLP-AIRNEAGVLTYPDGRQYAVAVFTRA -DADRRPAVDTSIGRAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces luteocolor TaxID=285500 RepID=UPI0008534269 ------------FAAAGVTGRLHALDIDSGAEV-DAGADQPVVTASVHKLCLLVTLHEQAA -AGVLDLTEQAECPAEGRTPGPTGLAAMLDPVMSLRDIAFLMMSVSDNTAADLLLERV-GL -DAVNATTARLGLERTHATHAFRELLAALDPARTNRSTPRDMTRLLRAVWRDEACAPEHGA -AIRRVLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -AGAILPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. YIM 98842 TaxID=2663533 RepID=UPI0013DC5225 ----------------------------D-GDI-GIEEEKVYSSASTIKVPILIEALRQAE -QGIINLDEKVTVTDEDITSGGGIIRHMSDNQLSLRDLLYLMITQSDNTATNMIIERV-GM -GSVNQASAEMGAEDTILQRYMMESVT--P--RDNLTSAKDMATIMQTVYEGDILSSESEA -EFLRMMAEGIL--SHYKGDDHSGVSLYSKGGSLGTNVRHNIGMFTHEDEA-VYVSVMSQN -AS--LKDSRIKMAEIGERVMDY- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=UPI001431CD09 ------ASIAEIFADAGATGFLHAREIGGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS -DAVNRVISDLGLRQTRLVGCCEDLFAAVHPIKTSHSTPRDVTTLLDALWTDTAAPAEACR -QARDIMAQQIW-PHRLSSGFPSGVRVAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASERQPLVDASIGR--------- ->[subseq from] Beta-lactamase class A n=2 Tax=Mycolicibacterium mucogenicum TaxID=56689 RepID=A0A495CTW7_9MYCO --dTLTAQIAEVAEDAGVFAFAHARDIDTGVEV-GFRSDDPTVTASVFKVPVLVEYVRQVA -AGELDPAQRIEVSPSEATMGPTGLSVFSDVAWSLRDIATSMITVSDNAATDIVTGLV-TV -DRVNSTMRELGLPGTQLTGDCSVIFDAATPEKTNRTTPREATSLLQQIWTDAAATPEACA -EARRILGMQVW-PHRLSAGFPDDVKISGKTGTIGM-VRNEIGVVEFPDGTRHAIAVFLRG -KTSRNPAADRAIGDIARLLSD-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A3L7PWA8_9BACT ----LRLEIEKEIKNFPGKVWISACNLNKGIAF-NLAGDERVRTASTIKLPILVALHGEVK -EGRLSWEEKLVVTKKTRAQGAGILLEMDDGHLTLREASKLMVVVSDNIATNLILERM-GI -DKVNAWMDKLQLPKTRSLAWIGEVVSRADGSTYGVTTPNEMVNLLTRLAQGEIISPEDSK -QILALMGRQQY-KDGIGRNMR-GASVANKPGALDR-LRSDVGIITVGKE-KFALAITLDD -MTPDWSPDNAALK---------- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7SLM3_9BACT ----LRRTLDSLASAHHGVVGYSVLDVDTGERL-SRRGDETFPTASLIKVPILVTVFDLVE -QGQLSLDDQLTLLKIDKVPGSGNLQFMHDNALTVRDAAWLMSVTSDNTATNLLLDRI-VI -RRVWDKMEKLGLPHTKVHSKTYLRMASSVKYGLGVTTPNEMVRLFALLAEGKAVSQKGDS -TMLDILAHNDD-FELMQRYID-GLTVPHKTGSTDQ-VRTECALFPLQSR--VVACVLTKE -NVDQDNEAQVTLANMGRAIAGAw ->[subseq from] serine hydrolase n=1 Tax=Lacrimispora aerotolerans TaxID=36832 RepID=UPI00047E82C1 ---TLEKRIEAEIKSYDGVMGIYLDDL-RGTVI-QIKADETFETASAIKTWILACLFWEAE -KGRACLEDQIEYKKEHWVDGSGVLGTLEPGALRVKDAATFMMIVSDNVATNMMIDYL-GL -DRINQCIRRLGSMDTVLHNPIHFDQ----YERLGTSTPRDYASIFVRLVKGELISPEADR -QMLEILKKQQY-QSMITKDFPPYITVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE -FSDAAHSATMFGARVSRLMLDQy ->[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. TaxID=2053611 RepID=A0A357Y1H8_9FIRM ---ALAAHIEALSNGDSTHYEVFVAYPLENREY--VYQSAPMRSASMIKVFILATAMERVK -AGTLALDQTLTLHSSDKVGGAGVIAGYASGTLSLDTVMRFMITESDNTATNMMIDLL-GM -DAINAYIQQHGYHDTSLQRKMMDSA-AVAAGRDNYTSAADLGHFFVTLYNRCCVSPELDD -VMLGYLAGQTD-TECFPAAMP-GVMIAHKTGELG-GLYDDGGIIYQEGR-PFIMVGMTEH -YS--------------------- ->[subseq from] hypothetical protein n=1 Tax=Prevotellaceae bacterium LKV-178-WT-2A TaxID=2606637 RepID=UPI0012B29246 -----------------------ACLIKDGQFY-GIHENKYFPMNSVMKFPQALFVADWMK -KHNIRLSDSVKVTKEELIDWSPKLGDIQTSKFTYAELLSYSLMLSDNNACDVLFKRCGDP -KTVEAYVRSLGFKRIHIRKTERQMREDHSCCRHNKTTPKDMTLLLQWLSSHH-SDTPILQ -FIWETMMKCKTGMERLPAAKHEGAMLLHKTGSGYTADIGDAGIYLLSDGSKLPICVFVKG -ASS-----DHIIAEISQ------ ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140B411E --------------------HVHAVALDRHREI-GVRADEPVVLASVFKLPLALAYARMVD -SGELSATDAVELVPGIRTPATGVAAMADPVTMSWRDAVRSMMTVSDNAAADAILDVV-GV -DRVAATLRDLGLTSTRVPGGTRDLYADAADPRNNVSTCREMTRLLSAIWTDRAASAQQCA -FIRSVMSQQVW-TQRLAAAFPDDVVVSGKTGTFV-ALRHEVGVVEYPNGESYAVAVLTMS -ARARLPAADDAIAQAARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI0013DBDED2 -----AARLDAAFADAGVTGWLHAVDIDSGAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTARLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLGSVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHMAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ZL-24 TaxID=1933029 RepID=A0A2S3XXD7_9ACTN -----ERTIRSLFDDAGVRGWLHVAELDRSARV-ALDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLAVQMMSISDNTAAHAVLRAV-GT -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces griseocarneus TaxID=51201 RepID=A0A3L8IRS1_9ACTN ----TTGRIRAAFAEAGVTGRLHAVDIDSGAET-GVDGDHRVVTASVHKLCLLVTLHELAA -AGRLDLTERIECPADTRTAGPTGLAAMLDPVLSLRDAAYLMMAVSDNAAADILLERV-GL -DAVNRTTARLGLARTHAVHTFGQFLAALDPARTNHSTPRDMTRLLGAVWRDEACTPEHGA -AMRRVLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASAVLPPADAVIGTAARLAVD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Shapirobacteria bacterium CG10_big_fil_rev_8_21_14_0_10_40_9 TaxID=1974888 RepID=A0A2M8L313_9BACT -----TLEISDLVKNLKGEYGIYVFNLTTKQGY-GVNEDEIFPAASLIKLPVFLTLYQEAE -AGRIDLSSKYTLKNSDKQAGAGGMQKSAGTVYTYRQVAELMGKQSDNTAFFILRKIL-GD -EKIQKTIDNLGMTKTSLVKNE--------------TTSQDLGLFFRKLYAGSIVSREHRD -EILGYLTETFD-ETRIPAGVPEGTRVCHKIGTDI-GVISDAGIVFSP--KPFILVIMSKN -VL--EKEAKEVLPKITEAVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter barkolensis TaxID=2053187 RepID=A0A2N0VFY8_9BACT ------EQILELTKGFNGDIGIYVKDLESGAEF-EVNADTIFPTASMVKIPILVKIFDKIE -QGELEYQMELDYGPEPEYEYSGISNLIPGTEVSLSELVHMMMSTSNNTASLWNQYLAGTG -TEINQWLADHGYVATRVNSRTEDRGEDFETYGWGQTTPREIARLVGQIYRGEVVSSHACE -QMYRIMSRNYW-DGEALSQIPPTVNVASKNGAVR-ASRSEVLLVNAPSGD-YLFSVITKN -QEDSDNEAWVLIRNLSALLYNHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC08241 TaxID=2487421 RepID=A0A429Q7P5_9ACTN ----IHTTLASVFAQARAEGLLHVRDLDTGAEF-GHGADAQVVLASVFKIPIALEYARQVA -AGELDPARRHTVTSAHRAGGSSTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIV-GP -DRVRATLDELGFPDFGFSSC-AALDDACAPGTSPSSTPREVTALLAAIWHDEAGPASACA -EVRDIMGQQVW-QHRLVSGFPPGVRLAGKTGTDFP-VRNEAGVIEYPDGRRYAVGVFLRT -STAAQPLADRAIGRAARAAVDH- ->[subseq from] Putative beta-lactamase (Penicillinase) n=1 Tax=Deinococcus deserti (strain VCD115 / DSM 17065 / LMG 22923) TaxID=546414 RepID=C1CYR0_DEIDV ------------QRGFAGDTGLRICDLDGTELY-ALNATRTFPAASTIKVPLLIQALQEAQ -TGRLNLRERVTLEAADRVPGSGILYELGAGLPSWLDLLTLMVIVSDNTATNLVIARL-GP -DEINSWLARGGWSSTRLIGRLEQQNEAQRRGERNRTSAHDQVDLLLRLANGALLDRTHTD -LALSILSRQQL-RDIIGRRVPRSYRLVSKSGELT-GVHHDVGILYTP--RPLVIALLSEA -GQREHPENRDVL----------- ->[subseq from] Serine hydrolase n=1 Tax=Lachnoclostridium sp. TaxID=2028282 RepID=A0A3D1FT08_9FIRM -------EIIKKLEQLPGKIGFFYENLKTGDGF-AHHEQEPMMAASVIKLFVMTAAFEKEK -KGTFQMDELFAVKREDCVPCGALTYLHDGILVTGMDLITLMIIFSDNTATNILIDIL-GM -DEINETIWGLGFRQTLLQRKMYDMESS-AQGIQNYITAYETGRLLKMMYDGILIDRQSSE -TMISILKNQQL-CSKIPFYLQDSPEIAHKTGEDT-GITHDVGIVYG--MEPFLICFCGNE -T--DTPAFERIMAEIS------- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537JI66_9BACT --kKLDSKIRSLVQDYHGDIGVYVKSLKNGSIV-TINADTVFPTASIVKVPIFVGVMDKIN -RGELFYDSSLIYKDSLLYEGEDILGSFKSDEILLKKVIMLMLTTSDNTASLWLQSLAGKG -TRINAILDSLGLKYTRVNSRTPGRETNRNIYGWGQTTPLEMGKLFEMIYRNQILSAAICE -RMMRCLGRNYWDEDEAISQIPPLIEVFSKNGCVD-ASRSEVLLVNAPHN-PYIFCIFTKN -NKTHFNEAWALARRISKLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-5630 TaxID=1463864 RepID=UPI000692608B ---AVADRIAAAFADAGVDGAVHAVDIDRGTQA-GHGADRLVCTASVHKLCLLLALHRLAA -AGRLDLTEQVECAVEGRTPGTGLAAMLDASRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTRALGLRHTRAVESFAAMQEALDPTHGNRSTPRELTRLLGAVWRDEFLPEAHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEAGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGLVARLAVD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X0WK93_9ZZZZ --eRLKKQIEGVIRGTEGEVGVAVKHLESGQEL-YINGDMNFPMASVFKVPILVEVLAQIK -EGKFTLKDEISIQKTDQHLGSGMLSDLEAPGLSLRNLITMMMIISDNSATDILLTKV-GA -ENVNNRLRSYGIGEITVNRTCQQLIMKFTQIMKDQSTPRAMNRLLEMIYKKEVVDEESCD -LILSVMLEC--------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_40_15 TaxID=1798376 RepID=A0A1F5Z080_9BACT ---EIKTDINKELANTTGTFSVYFYDLKTGDNF-GINEDIVLTAASVNKIPILAALYHLAG -KDEIDLDKIIVPQQKDIQDTGSMRYDKPGTPYSIKTLARLMMEKSDNTAAYLLASVIIGM -DEIQKLIEEWGLTQTDME--------------NNKTSVKDMFVITKKIYNGEISSEELNK -EMVDFMDDSDF-EDRISRGVPETITFYHKTGDEV-GKVHDVGIVDLPER-PYFLGILTTD -VT-DVEETKDKIARISRIVFS-- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A6ZJD8_9FIRM ---TLEKRIEAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFLLAALYLQVQ -RGKADLSEEIEYEQSQFVDGSGMLRAGVGAKLRVKDTATMMIICSDNIATNMLIDYL-GL -DAINACIRELGFAHTVLHNPLHF-DR---YRKLGTTTPRDYAALFARIAKGTLVSAQASA -EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Uncharacterized protein n=3 Tax=Ktedonobacter sp. TaxID=1932716 RepID=A0A3D2MRZ5_9CHLR -----QASIEQELSTLGGHVACVVIRMTDEQELvSINADHVFPAASLAKVPLLIEVARQVE -FGMLCWETRYLVWEGARVASDGVIADLSADLPTVQDLAHLMIAISDNTASNMLLDIV-GM -DAVNATMSNLGLTDTRIERRFIDFEAR-KAGYDNWTTAADMALLYSFFFTE-LLP-GKKK -MLKMLLRQND--YTILPAYWGEKTPFAHKTGGLA-GIIHDAGILYAPTHTPLIIVIMTSE -QV-DEPLTRYTLARVGRIIY--- ->[subseq from] Beta lactamase n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2QEI0_9PSEU ---AIAEEIEAVFAKAGARGFVHAREVGGGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRI-GQ -DAVDKVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTPREITELLDAIWTDRAGDPAACE -RVRAIMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRQPAIDSAIGQAASLAVEH- ->[subseq from] Beta-lactamase class A n=1 Tax=Hungatella effluvii TaxID=1096246 RepID=A0A2V3YAD8_9CLOT ----IEKRIEAELMSYDGTMGIYADDF-HGNVI-AIGAEEPFETASTIKTYILASLFDQVE -KGKASLEDMVEFKEKHTVDGSGVLCALEPGALRVKDAATLMIIVSDNVATNMMIDYL-GL -DTINACIHGLGCRDTVLHNPLH-FE---RYDKLGTSTPRDYASIFTRLAAGTLISPEADA -KMLEIFKKQHY-NSMITKDFPAVVNVASKSGSMN-ACRNDGGIIYTPYG-PYVLVMFNKK -FSDAAHPATVFGARVSRMLFDQf ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4FWL3_9BACT ----LRRTLDSLSAAHHGVVGYSITNLDTGEHL-EQRGNETFSTASLIKVPILVTLFDLAA -QKLLTLDDPIVLTEIDKVGGAGQLQYLRTPLLRLWDVAYLMSTLSDNTATNLVLDRI-KI -RRVWQKMEALGLAHTKVHSGSMTRIASSAKYGLGVTTPNEMAQLFTLLAQGKAVSPLADS -TMLDILANNQD-DSKLARY-TYGTRLAHKSGDVD-ASRTDCGVFTLPAR--VVACVLTKE -NTDTDAEGNAVIGRIGEAIVKAw ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW140 TaxID=368503 RepID=UPI000E0E6660 -------RWRQLAAQQDLKVSAFMLVLDDGRYA-ELNPDTALPAASSIKTPILLTTLELLD -SGSLRWNEPLTLTKPVVGGGAGWMATPLGTRFPTHEVATEMIRISDNTATNLLIERAGGK -KVINTRFNALGLSATEVNNWLPDLQGT------NTSSARDLARAIALVDTGKALSTRSRD -LFREVMGTSVT-NRLLPGGLLKGYRVYNKTGDIGI-AYADAGLIELPDGSRAVAAFMVQG -PFND-PRSTELIRNMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 7K534 TaxID=2530366 RepID=A0A4R4MSU3_9ACTN ---EVAERIEAEFRAAGVTGCLHVVDMDSGREV-AVRAGDPVVLASVFKVPLLVAFHRQAA -EGVLDPAEPVVLGPADRTAPTGISGMLDEVRMSLRDLTFLMITVSDNAAADAVLDRV-GR -DAVNAAAAALGLSDTVVEVSGRELHEALDPLRTSRSTPRDMTRLLSMIWRDEAAPPDGCA -AMRRLLGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGAVEYPDGGRYAVAVFTRS -LLAVLPRADAAIGTVARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces atroolivaceus TaxID=66869 RepID=UPI0009986049 --------------------HVAELN-SPSARV-TVDPGEQLPMGSVYKVPLMVAFCRLAD -AGLIDPGRRLTLEPGERVPPTGISILHDSVTMSLRDLVVLMMTISDNTSADAVLRAV-GA -EVVDAMCRDLGMPDTHIRGGVVTTFSVYDPAFKASTTPADMARLLRAIWTGRAASDERCA -FMRDVMRRQPW-THRLASGFPDDVTVYGKTGSFG-ALRHEAGVVELADGSTYTAVVFTQA -ARAKLPRADAVIGAAARTAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Beckwithbacteria bacterium CG10_big_fil_rev_8_21_14_0_10_34_10 TaxID=1974495 RepID=A0A2H0W846_9BACT ----LENSLNFLLKDLQGEYGFYYFNFNTKEEL-GINENQVFQAASVNKLPIMISFYQEVE -KGNLKIDSLYVLDKEDFQDGSGVLHTQEQGIYSYEELVKLMGKHSDNTAAYVMARIV-GY -KKIRDYLDKYEMNNTTLDD-------------NNTTTPKEMGNYLRLFYENELIGVENKE -KILEFLTQTDF-EDRLPQGVPSYIRVAHKTGNLA-GVYNDCGFILSS--KPYLVCVFSQD -TLE--QQALDVIPKIAEILWEY- ->[subseq from] Uncharacterized protein n=1 Tax=Sulfobacillus thermotolerans TaxID=338644 RepID=A0A3S6Z2E4_9FIRM ---NIHQAIAQWSQHFSGRFTLYAEHLQTHEVV-AHEPTRLMETASVIKLPIMIAAMDQVE -AGHLDLATPLVYTRDDYVEGSGVVQNLTPGFLSLHDALTLMITVSDNVATNMVLRQI-GL -ETVNAVMHRLGTPHIHLYKRIDFAQ----PGPIGLAPAEEIGVLLKSLYHRTLISPWASG -IMWDILTRQQY-NTIMTRELPYHVQIGSKSGSLE-GIRNDVGIVTSKWGD-YTVAIFSAE -CEHVDNEAMRLLPRLTRLLFDHf ->[subseq from] Serine hydrolase n=1 Tax=Arsenicibacter rosenii TaxID=1750698 RepID=A0A1S2VDS4_9BACT ---KLERLLRDALAGFRGDVGVYVHHIKSGKTV-SINADTTFPTASTIKIPIMCGLFDKIN -KGELKYQQEIVYKDSLHYDDGIVGSLKDGAKFPLSQIVMLMETISDNTGSLWCQALAGGG -TAINSWLDANGFSKTRVNSRTPGREAFRPTYGWGQTTPHELAELLLYIRQGKAISPDASD -RMYRNLGRQFWDGDGL-SQLPEGIKVATKNGAVNR-SRSEVVLVHAPHGE-YVYCIMTKN -QQERTNEGATLLRKVGALLWHYy ->[subseq from] serine hydrolase n=1 Tax=Spirosoma panaciterrae TaxID=496058 RepID=UPI00036792F6 ---RLERKLQSALAGFRGNVGVYVYHIRSGKRV-SINADTLFPTASMIKIPIQCGVFDKIH -KGELSYNQELVYKDSLHYDDGIVGSLKDGARITLSKVVMLMETVSDNTGSLWCQALAGGG -SAINTWLETNGFHQTRVNSRTPGREANRTQYGWGQTTPHEMAELLVYIRQGKAVSPDASD -EMYRNLGRQFWDGDGL-SQIPPDVKVATKNGAVNQ-SRSEVVLVHAPHGD-YVYCIMTKN -QQERTNEGYELLRTVGALIWHHf ->[subseq from] Beta-lactamase class A n=1 Tax=Microlunatus soli TaxID=630515 RepID=A0A1H1UDK5_9ACTN --qEFTRRLDVLLAAADVRGWVHAVDLDSGASL-EAGADQPVVAASVFKLPVLVELFRQIG -VGRLDARQRVRIGADERRTPTGLSV-MLDDVLSLRDLGYAMMSVSDNRATDVIVDLV-GL -DAINNTQAELGFPATVLEGDCQFLFDVFDPLRTNRTTPRSTTALLAMLWRDEILDPSACA -EIRRILSLQVW-PHRLTSGFPDEISVAGKTGTIGP-VRNEVGVVSYPDGGRYAVAVFLRQ -REYHNPVADAAIGQVGRLAIDH- ->[subseq from] Beta-lactamase n=1 Tax=Sphingobacterium sp. JB170 TaxID=1434842 RepID=A0A1R4KKN4_9SPHI --kKLTKIIEQEIASFDGEIGIYVENFKKDITV-EIQADRIFPTASIVKIPILVGVFDKIN -DGSLNLSNSYIYDAKREYGGSGLMQFFKDSATDLSTIVSLMLSYSDNVASIWCQELAGGG -QNINRIMDELGLKNTRVNSKTAGREDDWNQYGWGQTTPKEIATLLAKIRFKKVYDNRLSD -KMYRYLKNQFY-NERSLSQIPAEIATASKTGSVNE-SRGEVVFVHAPSGD-FVFSILTKN -NKTPDNEAEVLTRKIAKLLWNYf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A149U6W1_9PROT ----LAQSISKTVKAQPGHFAVYAALSGHSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHAQDTVTVHNRSLVGNGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD -LP-DEQAGIKVLNTLSQQTYTYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces atriruber TaxID=545121 RepID=UPI0006E3F336 ---------------AGVTGRLHAVDIDSGAEL-DAGADQPVVTASVHKLCLLVTLHQQAA -DGELDLTEQVECPAGLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL -DAVNATTAALGLDRTHARHTFSELLAALDPARSNRSTPRDMTRLLTAVWRDEACAPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -AGAILPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura echinospora TaxID=1992 RepID=UPI000CDF1554 ----------------GVVGCLAAIDLDDGRLV-GVRADRPVVIASVLKVPLLVALHRQAA -AGIVDLSEQVVLRPGERTTPTGVAVLQDEVRMSLRDLAAMMITVSDNAAADTLFARV-GV -ETVNAVLAELGLHRTHIPGCCRELFDALDPARTARSTPEEIAQLFAAIWRDEAAPAAECA -RMRRLFGLQVW-PHRLASGFPDDVQVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS -LSSVLPRADAVIGTTARMAVEH- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0001F41FEE --qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Serine hydrolase n=1 Tax=Goodfellowiella sp. AN110305 TaxID=1892852 RepID=A0A5B2XE67_9PSEU ---AVAEEIAAVFADAGARGFLHAREVGGGPEM-AVGADDPVVLASVFKIPVAVAYAREVA -AGRLDETERTRVGARYRTGGIGTAGCADDVELSWRDLARFMLTMSDNAATDVVFHRI-GQ -AAVDRVLTDLGLTRTRLVGCCEDLFAVLDPDRSTASTPREITELLDAIWTDRAGDPSACE -RVRSIMAEQIW-PHRITSGFEPGVRIAAKTGTLP-AVRNEAGVVTYPDGRRYAVAVFTRA -HSDRQPAIDSAIGRAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=UPI000D0C7D79 --------------DAGVTGWLHAVDIDSEAQV-GAGADQPVCTASVHKLCVLVTLHELAA -AGELDLTERIECPPTGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTAARLGLTRTRAVYGFGEMLGALDPARTNHSTPRDMTRLLGAVWRDEACPPEYGA -AMRRIMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED169 TaxID=1986593 RepID=A0A1Z9JA23_9SYNE ---ALSRRLAEIASQKDXKVGAFVLVLDNGTYA-ELHPDRPLSAASAIKTPILLVALEALD -QAKLTLXEALSLXKTVVGGGAGWMGGQPXGSFSVLEVATEMIRVSDNTATNLLIQRLGGK -QALNSRFLELGLEGTVINNWLPDLKGT------NTTTPRDQARAIALVETGQALSVRSRD -LFRQTLGTSRT-DTLIPRGWLRGVRAYNKTGDIGI-AYVDSALLELPDGRRVVASYMVEG -PFND-PRSTNMIRALAAA----- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI0007AB3F9D -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIRRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIIRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI0009B8F658 ---------AQVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH -DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTIAQLIQLMVVESDNTATNMLIDKL-GM -ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA -FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS -NEG-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429E8X8_9PSEU ---AIADEIEAVFAEAGTRGFVHAREIGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRIDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLARTRLVGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPSGVAIAAKTGTLP-AVRNEAGVVTHVDGRRYAVAVFTRA -ESDRQPAVDSALGEAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Ferruginibacter sp. BO-59 TaxID=2294116 RepID=A0A3M9NDW9_9BACT ---RLQAMLTRLVDGFHGDVGIFVYDLAKNKIA-SVHGDTIFPTASMVKVPILTGLMHKIH -NGDFTYHQEMLFTDSVRYSGQEILASFRDSTIPLNELVMLMMSMSDNGASLWLQGLSGGG -AQINSYMDSLGLKYTRVNSRTAGRKENYNLYGWGQTTPKEMATLMKMIAENKIINQQISE -RMLRMMSRQFW-DEDAISQIPPNVFVADKSGAVD-ATRDEV--LYVNGNHPYIFCVCTKN -NREHDNEAWVLTRKLSALLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Niastella populi TaxID=550983 RepID=A0A1V9FTJ5_9BACT --hRLQQQIEALVKDLHGDIGVYIKNLRTGKVA-MVNADSIFPTASMVKVPILIGIQDKME -SGQLEYHQQLEYKDSLLYAGEDILGSFKSGEIGLHKVLMLMLTTSDNTASLWLQSLAGTG -TRINELLDSAGMKFTRVNSRTPGREANRQQYGWGQTTPREMGTLMEKIYRGEIISKKAGE -KMIRLLGRNFN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPGG-PYIFSVQTKN -LQDNSNEAWVLTRRLSALCWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Nocardia sp. CS682 TaxID=1047172 RepID=A0A4P7HB89_9NOCA ------------------------------------------------------------- ------------------------------------------------------------- --------RGLGDPVSRMDQYEPELNRDPPGDDRDTTTPRAIAADYQQLILGSALPEDKRT -ILTDWLVRNVTGAKRIAAAAPAGWTIADKTGTGDYGRANDIAIVWPTAHPPLVLAIMSDR -TGYDAEPSSELIAEAARHIF--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. AW19M42 TaxID=1379686 RepID=UPI000D12A41E ------------------WLHVAELHHPSARVV--IDPGEQLPLGSVYKVPLMAAFCRLAD -TGRIDPRHRVTLESADRVPPTGISVLHDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA -GVVDAVCRDLGMPDTRIHGGVVTTFSVYDPAFKASGTPADMARLLRAIWTDEAASAEGCA -FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Kryptonium thompsoni TaxID=1633631 RepID=UPI000707E2B9 -------------------IGVAVKNLETGETF-FINENLIFPQGSAIKIPILIEVIKQAS -EGKFKLTDKIKIEKKHQVGGSGVLKEFGDGTLSIYDLAVLMITVSDNTATNILIDLV-GM -ENVNKTLEKLGLKNTKLQRKMIRPDAS-ARGEENLSTPLEAMKLMEMLYKGEVISKEISN -QVIDILKKKKR------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. A7024 TaxID=1128680 RepID=UPI0013EB1EFD -------RIQAAFTDAGVTGRLHALDIDSGAEI-DAGGNRPVVTASVHKLCLLVALHERAA -AGQLDLTEQVECPADGRTAGPTGLAAMLDPVISVRDLAHLMMSVSDNAAADLLLDRV-GI -DAVNATTDRLGLAATRMSHTFGGLFAALDPAHSNRSTPRDLTGLLRAIWRDEACPPPHGA -AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-VRSEAGVVEYPDGGRYAVAVFTRA -ANATLPQADAAIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. YR332 TaxID=1855298 RepID=A0A497YMY9_9SPHI --sKLTAKLNDAVKDFHGQVGIYVRNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS -EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTMIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NATPNNEAGLLIKKISALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sediminis TaxID=1493691 RepID=A0A5R9KAC4_9BACT --qKLTAMLEKALAGFHGNAGVYVRNLKTNQTA-AIHADSIFPTASMIKVPIMCGLFDKIS -KGEIRFNQELVYRDSLKYDNGIVGSFRDSTRIALPKVVHLMISQSDNTGSLWLQAMAGGG -AAINQWLDANGFANIRVNSRTPGRKEGQAKYGWGQTTPKEMAELVAMIRNGKAINAAASE -RMYRYLGMQFW-DGEAISQIPPYIKTAAKSGAVNQ-ARSEVLVVHAPHGD-YVFCVSTKN -QQQQNNEGYTLIRKVSEIIWNHf ->[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI00109CE46D -------DIQEIFTDAGATGFLHAREVEGGAEV-SVGADEPVVLASVFKILVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFADDVVASWRDLALNMMTMSDNAATDVLYHRL-GT -EAVNRVISDLGLRQTRLIGCCEDLFAAVHPVKTSHSTPRDVTTLLNALWTDTAASAKACR -QAREIMALQVW-PHRLTSGFPPGVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Microgenomates bacterium TaxID=2093373 RepID=A0A3A4ZH15_9BACT ---QLLEQIKKSFETEKGSYSIYIYDLKSDSGF-GLNESAIFTAASVNKIYILAALYHQAD -QGKLDLDEDITIQSKDIQDGTGVIRYQGAGTYSLKTLAQLMIEKSDNTAAFVLTNII-GA -NTIQQLVNDWGFIQTDIDN--------------NKSSNKDVAGMFLKIYRGEVTDQAHTQ -EMIGFMDDSDF-ENRLPKDLPKNINVYHKIGSEV-GVIHDAGIVDLPEH-PYYIGVLTND -IS-DIEGTENKISEISKMVFDYf ->[subseq from] Beta-lactamase n=1 Tax=Kerstersia gyiorum TaxID=206506 RepID=A0A171KN27_9BURK ---RLAQGLAPILAGTQARVTMAVHALDGTPLF-EREAGTAMPSASLIKIPILMLLLEQVA -AGRWPLDHMLSLEHTERVGGTGILNQLPSVRLQLEELGRLMIVLSDNVATNALIDWL-GL -DDVTQWCQRAGLPQTRLERRMMDAQAR-AAGRDNWTSAADACAALLWLLRNGSLPAPLRQ -LGLQMLADQRE-QSHFGAALPAHAKLANKTGQLH-GLRHDAGILSAGG-QSVVLAVLADG -FTDP------------------- ->[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. HC2 TaxID=2714892 RepID=UPI00140AC5C2 --rKLTQQLNDVVKGFHGQVGIYVQNLKTGKVA-AINADTLFPTASMIKVSIQCGLMDKIE -KGELQYNQKLVYRDSLLYKGEDILGSFKDKDIQLSKVALLMITMSDNTASTWLQKLV-GG -EYINNWLQQNGFKVMRVNSRVPGREAIRSIYGWGVSTPFEMCRLFTMIRQGKAVSAAASE -RMSRNMARIYW-DEKALSQLPPYVQTISKQGAVD-AAKSETVLVSAPHGD-YVFSIMTNH -NTDQDNEASVLIKKISALLWHYf ->[subseq from] Beta-lactamase class A n=1 Tax=Kerstersia gyiorum TaxID=206506 RepID=A0A4Q7MDH5_9BURK ---RLAQGLAPILAGTQARVTMAVHALDGTPLF-EREAGTAMPSASLIKIPILMLLLEQVA -AGRWPLDHMLSLEHTERVGGTGILNQLPSVRLQLEELGRLMIVLSDNVATNALIDWL-GL -DDVTQWCQRAGLPQTRLERRMMDAQAR-AAGRDNWTSAADACAALLWLLRNGSLPAPLRQ -LGLQMLADQRE-QSHFGAALPAHAKLANKTGQLH-GLRHDAGILSAGG-QSVVLAVLADG -FTDP------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces pactum TaxID=68249 RepID=A0A1S6JA18_9ACTN -------RLHAAFADAGVTGWLHAVDIDSGAQV-EAGADQPVCTASVHKVCVLVTLHELAA -AGVLDLTEQVECPPAGRTPGPTGLAAMLDPVLSLRDAAFLMMSVSDNTAADLLLRRV-GL -DAVNRTTDRLGLTRTRAVYGFGEMLGALDPARTNRSTPRDMTRLLSALWRDEACPPEYGA -AARRVMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRT -AHAVLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=cyanobiont of Ornithocercus magnificus TaxID=2496102 RepID=A0A4Y3FT76_9CYAN ---TLSQRWRELASEEDLIASAFVLILDDGRYA-ELAPDVSLPAASSIKAPILATALELID -TGELQWHEPLVLNREVVAGGAGWMAKPLGTHFPAYEVVTEMIRVSDNTATNLLIQRIGGR -EALNNRFSVLGLDSTVVNNWLPDLEGT------NTTSARDLARSIALVETGEVLRPRSRD -LFRGVMETSVT-NTLLPMGLLQGYKIYNKTGDIGT-AYSDVGLIELPDGRRAVAAFIVKG -PFN-DPRSAELIRNFAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B8DA80 -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNILRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229S1V6_9PSEU ----IVERIEAVFAKAGARGFVHAREVGGGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYYRV-GQ -EAVDKVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTPREITELLDAIWTDRAGDPAACE -RVRAIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTFVDGRRYAVAVFTRA -DSDRQPAIDSAIGEAASLAVEH- ->[subseq from] Beta-lactamase n=2 Tax=Clostridiales TaxID=186802 RepID=A0A084JR15_9FIRM ---TLEKRIEAEIKSYDGKMGIYLDDF-HGNVI-AIHADEAFETASSIKTYILACLFDEVE -KGNKSLDDIIEYKVEHAVDGSGVLAAEPGAKLRVKDAATFMIIVSDNIATNMMIDYL-GL -EKINQCIKALGCRDTVLHNPIHF-E---QYDRLGTSTPRDYASIFIRLAKGELISPRADE -MMLEILKKQHY-NSMITKDFPSFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] Uncharacterized protein n=2 Tax=Rhodococcus TaxID=1827 RepID=X0Q6H5_9NOCA --------------------------TEDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFHDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVELALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Beta-lactamase protein n=1 Tax=Heliobacterium modesticaldum (strain ATCC 51547 / Ice1) TaxID=498761 RepID=B0TAI9_HELMI --dKLRQRIRKEMAESGIDYALFLEDLENGNQF-AIEPDKNFQAASAIKVPLVLFLYALAL -DKRLDLDETMTLTSSDLAPSSGGLWSYLPGRYTLRQLAKHVIEDSDNTAANMLMRRV-GR -SNFYLFLRLAGARTV------PAG----PG-KGNVTCARDMALYLKGIWVFRQLNPGFGE -EIFQYLLHSKI-DNRIPAGVPDDIKVANKIGSQI-GFFHDAAIVLLPNR-PYVLAILCHH -PSE--TEANAAIARISRIIYE-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A352CHN3_9BACT --kKLEARIENIVQGFKGEVGVYVKDLRSGRVS-TYHADTIFPTASIVKVPILLGITAAVQ -NGQLAYDSNHVYRDSLLYAGEDILGSFKDGEIALKKIIMLMMTTSDNTASLWLQSLAGGG -QRINALLKEQGLSSTFVNSRTVGREANRAQYGWGQTTPQEMGFLLEKIYRKEVFSSYASE -KMLRAMGRNFWDEDESIGCFPPYVEVFSKNGCVN-ASRSEAMIVNAPHR-PFVFCIFTKN -NQTHDNEAWSLARKMATMLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. ZH6 TaxID=2482727 RepID=A0A3E2NY34_9SPHI --eKLTDKLKEAVAGFHGQAGIYVHNLKTGKTA-GINQDTLFPTASMIKVSILAGVMDKIE -HGELKYNQKLAYRDSLLYAGEDILGSFKDKDIMLSKVTMLMITMSDNTASLWLQKLV-TG -QHINNWLDSNGFKSMRVNSRVPGREAMQKRYGWGVTTPYEMCKLFTMIRDGQAVSRAASE -RMYRTLNRIYW-DEKALSQIPPYVQAISKQGAVDD-AKSETVLVNAPHGD-YVFSITTKN -NTTADNEASQLIKKISAMLWHYf ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus wratislaviensis TaxID=44752 RepID=A0A3D9R5H9_9NOCA --------------------------TEDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFHDPVVLSWRDLALSMMTVSDNAAADLVLGHV-GL -ESVELALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Crenotalea thermophila TaxID=1393122 RepID=A0A1I7NJX5_9BACT --rKLQRKLEALVKPFQGTVGIYVHKLGTNKEA-AIHADSLFPTASMIKVAIQAVIFQRIA -DSQLQYHQNLLYRDSLYYPGVDILGMAKDSTIELSKVVMLMITESDNTAALWLQSLAGGG -TAINQWLADHGYQYYRVNSRTPGREAAYRQYGWGQTTPREMAQFLVQLRKGEIISPAASE -RMYRNLCHIYW-DDVALSQIPPYVQAASKQGAVDD-SRSEVVLVNAPHGD-YVFCVDTKD -IATHSNAAWELIRQVSALLWHYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 25 TaxID=1827542 RepID=A0A4R8H8K4_9ACTN ----TLRRIAAAFAEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQQAA -AGLLDLTEQVECPPADRAAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DAVNGATARLGLNRTRAVHTSRSLFAALDPARSNRSTPRDMTRLLTAVWRDEACTPEHGA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ASATLPAADAVIGTTARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2B2X0_STRVZ -haAARRRITTAFADAGVTGQLHAVDIDTGTAL-GVGSDTLVPTASVHKLCLVATLYRQSS -LGLVDPTRPVDIPAENRAPGATGLSAMRDAALSLRDLASLAVAVSDNTAADLLWDTL-GL -DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLTAVWRDEVCPGEYGE -ELRAVLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAVIGGAARIAVD-- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=Sphaerobacter TaxID=2056 RepID=D1C8L0_SPHTD ---EFDRAAQRVVSRFSGELGFAAKNLTTGEEL-GINAECVLPTASVIKTAVLVELMRQAH -EEGLDLQERMTMTASDIVGGSGVLKELGPGLPTVADVAMLMIIVSDNTATNMLIDRVGGV -EAVNRTMQEYGLRSIVLHNRVDF--EVIGNDIRAEASAADLVRLHEMMARGELINAEACR -QMIDVLSRQQYLD-QVPRYFNQSFTVANKTGFFP-GTRVDSGLIMLHDGPTIAFAAMTHR -SV--------------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Echinicola TaxID=390846 RepID=L0G2B4_ECHVK --kKLTAALNSVFEGFKGTAGIYVEHLPSGKYA-AINADTIFPTASIVKIPILIGVFDKIE -KGELDYHEPLVYRDSIKYGGSGLMQYFEDSTTDLSTLLALMISYSDNTTSLWNQALAGGG -ETINPLMEQYGMVSTRVNSRTPGRDKDWEKYGWGQTTPREMATLLKKMRKGELISQAASE -RMYRLMTNVYY-DDYALSQIPPYVQTASKQGMVN-ASRSELVMVNAPHGD-YVLYIATKN -NEEPDNESWVLARKVSALLWNYf ->[subseq from] serine hydrolase n=1 Tax=Spirosoma spitsbergense TaxID=431554 RepID=UPI0003720A40 --kKLEQKLKTAFASFRGDVGVYVHNLRTGKTV-AINADTLFPTASTVKIPIQCGLFDKIQ -QGELTYGQELVYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG -AAINDWLETNGFHQTRVNSRTPGRKANQAQYGWGQTSPRELASLLTYIRQGKAVSPAASD -EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-ARSEVVLVHAPHGD-YVYCVMTKN -QKERTNEGFTLLRTVGAILWHHf ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus radiophilus TaxID=32062 RepID=A0A431VPS2_9DEIO -------------SGFGGTVGLLIQD-ETGHEIcSLNADRVFPAASLIKVPLLILGLQAVQ -RGGLALEDRLPLPAAEQVPGAGVLHELGPGLLSWQDLLTLMIIVSDNTATNVVIDCL-RL -SAVQAALPGLGLAHTRLVGKLERYNAAQRRGERNQTTPRDMLRLLQRLRRGEYLDPVHTA -LALDILGRQQL-RDLIGRRVPCGYRVLSKSGELT-GVHHDVGWLLTP--RPLAVACLSQG -GEDAR------------------ ->[subseq from] serine hydrolase n=1 Tax=Spirosoma luteum TaxID=431553 RepID=UPI00036D5048 --kKLEQKLQTAFANFRGDVGVYVHNLRTGKTV-AINADTLFPTASTIKIPIQCGLFDKIQ -QGELKYGQELIYKDSLHYDDGIVGSLKDGSKIPLSEVVMLMETVSDNTGSLWCQALAGGG -SSINDWLETNGFHQTRVNSRTPGRKANQAQYGWGQTTPRELANLLTYIRQGKAVSVAASD -EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN -QKERANEGFALLRAVGAVLWHHf ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=UPI00131515F0 -------RIADAFLAAGARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVGKRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVLYHRV-GQ -AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAAEPAACE -RVRAIMARQIW-PHRISSGFGSDVKIAAKTGTLP-AVRNEAGVLSFPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura chibensis TaxID=392828 RepID=A0A5D0NPJ0_9ACTN -----NERIEDEFGAAGVAGWLHAVDVDTGREV-SVGADEPVVLASVFKVPLLVAFHRQAA -SGLLDPSEQVTLRPEDRTAPTGVSGMLDEVRMSLRDLTFLMITVSDNAAADVVLDRV-GR -GAVNATAEALGLPGTVVEVSGRELHEVLDPLRTSRSTPRDMTRLLSLIWRDEAAPAEGCA -AMRRVFGLQVW-PHRLSSGFPDDVLVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LLAVLPQADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. GEYO TaxID=2575511 RepID=UPI000E0E872A ----LSERWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD -AGRLSWNEPLQLSKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ -EALNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSIT-NTLLPRGLLHGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter sp. 2789STDY5608607 TaxID=1806497 RepID=UPI0006C8C148 --qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA -KGRYALEQPLALPASERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FT--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus koreensis TaxID=99653 RepID=A0A1H5CIZ0_9NOCA -----------------------------AGDI-AVGADDVVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGRV-GL -ESVERSLSDLGLTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGAQGE -FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA -ARTDLPVVDAAIGHVARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI000412EF4F -----AAAIEAVFANAGARGFVHAKEIGGGPEV-GVGADDPVVLASVFKIPVAVAFAREAA -AGRLDDTERVRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVIYHRV-GQ -DAVDRVLTDLGLERTRLIGCCEDLFAVVDPERTTSSTPREITTLLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAEVAIAAKTGTLPS-VRNEAGVVTHVDGRRYAVAVFTRA -ESDRLPAVDSAIGEAARLAVEH- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia mexicana TaxID=279262 RepID=A0A370H2E9_9NOCA --------IRAVFADAGCTGWLHARRCGDAAEI-SVGGRSRVVMASVYKLPLVVAFCRGVD -AGLIDPTAHLTVRPSDCTPPTGIAALHDPVTLSRRDLATSMMTVSDSAAADVLLGEI-GL -AAVEELLGEIGLTETQVVGGTADQLRAYDPAFASATTPEEMTRFLCAVWSGGVLSAGQTD -FVKSVMRRQIW-PHRVAAAFPRRVSVAGKTGTIG-AIRNEVAVVEFPDEYPVAVAVFTRA -ARADLPVADAAITEAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI00064E8DFF -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIRRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006BF1D9A --qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] serine hydrolase n=1 Tax=Desulfallas alcoholivorax TaxID=265477 RepID=UPI00040F545A ----LDQSVSEYLSDQKGTYGLYFIDLKSGKEF-GYNQYTPFHAASTFKLPMNLYLYTQAE -KENINLDQKLTSQSHHMEGGTGFLKNYPPGKYTIKQLATYSIVNSDNIATNILLERL-GR -EKVKSYMRSLGGKVV--------------VDGKNVTCPYDLALYMQKTIEFYRTDSPEAK -MLMENLINSEF-KDRIPAALPPNTKVANKIGNWPTNTYNDVAYVNHPVR-PYILAVTCSD -TP-GYGTAVPVIRQVSKMIYEY- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora antimicrobica TaxID=455193 RepID=A0A1I5KE73_9PSEU ----VERRIREVLADAGAEGWVHATQFGGGREI-CVGADELVVTASVYKLPLLVAMCRAFD -AGRLDPRATVRIDPTSCTPPSGFSTFLDPVTVSWRDLAASMIAVSDNSAADVILGAV-GL -DAVADVLDDLGLTRTRVVGGTADQHAAYDPAYAGATTPREMTRLLELIWTDAVASPQQCA -FIRRLLGNQIW-MHRVRSGFPQGVRVAGKTGTIG-AVRNEVSVVEFEGEEPVAVAVFTLA -ARADLPRVDTAIGECA------- ->[subseq from] serine hydrolase n=1 Tax=Acidobacterium sp. S8 TaxID=1641854 RepID=UPI00131C0E37 ---TLEAQLQAIAQTHHGHVTLFAHDLKSGKTA-AMNADTPAPTASVIKLTVLFEALKQIQ -EGKAHFDDRLTLTKENQVEGSGVFMFFDTPQFTLKDVLTMMVIVSDNTATNLAIDHL-GL -KNIDDRIQWLGLKNTWLYKKVSLMPADQKQFGLGKTTAREMAEVMERFATGNVAKPTADE -KLCDHMLKNQFYRNSIPRYLEGESKIANKTGALDK-VRNDVGVVFAKNG-PVIISMFTYE -NETPDNQAEVLMAKLAHTIVDRw ->[subseq from] serine hydrolase n=1 Tax=Deinococcus deserti TaxID=310783 RepID=UPI000A03E980 ------------QRGFAGDTGLRICDLDGTELY-ALNATRTFPAASTIKVPLLIQALQEAQ -TGRLNLRERVTLEAADRVPGSGILYELGAGLPSWLDLLTLMVIVSDNTATNLVIARL-GP -DEINSWLARGGWSSTRLIGRLEQQNEAQRRGERNRTSAHDQVDLLLRLANGALLDRTHTD -LALSILSRQQL-RDIIGRRVPRSYRLVSKSGELT-GVHHDVGILYTP--RPLVIALLSEA -GQREHPENRDVL----------- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. ACS1 TaxID=2028570 RepID=A0A2A3F7A9_9NOCA ------------------------------GDI-AVGADDVVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGRV-GL -ESVERSLSDLGLTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGAQGE -FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA -ARTDLPVVDAAIGHVARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-1521 TaxID=1609100 RepID=A0A0X3X4Q3_9ACTN ---DVQRAIRGMFADAGVRGWLHVAELHREARV-TVDPDEPVPVGSVYKVPLMAAFCRLAD -AGALDPRQPVTLGPDERMPRTGISILRDPITVSLRDLVVLMMSVSDNTSADAVLRHV-GP -AAVEELCRDLGLPDTHILGGAATTFEVYNPLSKASSTPSDMARLLRAIWTDGAASAESCA -FMRETMGQQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGGVYTAVVFTQA -ARADLPRADAVIGTAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI000532B730 ----------------RSNNGLIRIHIEGKESI-QINSFIKQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A127SLF1_9BACT --sELENRIDSLLNCKKATVGIAVW-TDKGDML-RYNDHVHFPLLSVFKFHVALAVLDKMD -KQSISLDSIVSIKASQMPPYSPLRKKFPDQDITLRELMQYSISQSDNNACDILIEYAGGI -KHINDYIHRLSIDSFNLSETEDGMHSSFEAVYRNWSTPSAMVRLLRTADEKELFSNKE-- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Bacillus TaxID=1386 RepID=UPI00064ACABB ----------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1K1PYC6_SELRU ----------QVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH -DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTVAQLIQLMVVESDNTATNMLIDKL-GM -ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA -FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS -NE--------------------- ->[subseq from] Serine hydrolase n=2 Tax=Acetobacter persici TaxID=1076596 RepID=A0A1U9LI62_9PROT ----LAQRMAETVANQPGHYAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYAAFA -KGTLHPDDTLTVHNRSLVGKGHFTYAQVGKAVPVSELLRLMIQYSSNLATNLMIEKL-GV -LPIRSVVNAQGLNGIIFGRMIEDFDAD-AQGIRNRVSARGLGSFLQKLNNGQIVGKTQSQ -SMIRIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVRNDAAIVTLPDGRQYILVVLTSG -LP-DEQAGIKVLNTLSHQAYLYf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=A0A5Q0D5M4_BACME -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGSDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis NBRC 101654 TaxID=749388 RepID=F7VDT5_9PROT ----LAQSISRTVKAQPGHFAVYAALSGHSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPQDTVTIHNRSLV-GSGTFYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSLVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD -LP-DEQAGIKVLNTLSHQTYTYf ->[subseq from] class A beta-lactamase n=1 Tax=Kineococcus sp. T13 TaxID=2696565 RepID=UPI00141200B6 ----------------------WALDLRTGARL-AHRADVPRPLLCLHAGLVAARLLRTGG ---PAVLRRHLRFSPDDLVDGSPVCCWHLSDGMSVEQLCDAALRRADATAANLLLGLVGGP -RGFTRSCRELGDRTTRLDRWAPESSGGQPWEPRDVTTATALARGYGRVLVGTALPAPARA -QLRSWLAT---------APLPGGWCFTHAAGTGWYGSAAVVGLAQRGAR-TVLVSVLTRS -GQPSTRGSARTARAAAA------ ->[subseq from] Beta-lactamase class A n=2 Tax=Rhizobiales bacterium GAS191 TaxID=1882830 RepID=A0A1H4W700_9RHIZ ----ASDIVAALRDRDGIDVGFSAIHLASEQCL-EINASSLFPTASVFKVPVMVEVFRQAR -AGIFAMSDRLTLATCHKTLTSGVLVTLDDGLPTIGDLVMLMTIVSDNTATKLLLDLV-GM -DKVNAAMAGYGLHDIHVAIDVHEMFLTFSRERDNTASAADMARLMAMIAAGEVVDAEACG -SMVAIMKEQQY-SERVPRYLPFG-SVANKTGTMR-GVRNDSGIMRRGEGDDIAYTVFTFD -PTPLAAGNSRFLAE--------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ766 TaxID=1169157 RepID=UPI00037C0795 -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRIDLTTVVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGAQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. ET3-3 TaxID=2675851 RepID=UPI0012FC1F48 ----------EIFRTAGVEGRVHARCFDCDGEF-GWGADEPVVLSSVMKVPLVLEFARQVA -AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAAYFAITVSDNTAADLLFDRV-GV -ENVRSLVRELGLVNTRIVGSLRDILYAVDPLRTTASTPREMTRLLQLIGEDRAGLPEACE -WVRDLMRRQVF-GHRLPSGFPPGTDIWSKTGTLP-GIRNEIGVVGYPDGSRYAVAVFTVS -QSGRQPAVDRAIGEAARQAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter frigoritolerans TaxID=652788 RepID=A0A562UGU1_9SPHI --kKLTVKLQEAIKGFDGQVGIYVQNLKTGKTV-TINADTLFPTASMIKVSIQCGLMDKIE -KGEIQYNQKLVYRDSLLYKGEDILGSFKDGDIEVSKVAMLMITMSDNTASLWLQKLV-GG -EYINNWLDQNGFKVMRVNSRVLGREAIRAKYGWGVTTPYEMCRLFTMIRQGKAVSAAASE -RMSRNMGRIFW-DNKALSQIPPYIQTISKQGAVD-ASKSETVLVNAPHGG-YVFSIITNN -NKTTDNEADILIRKISALLWHYy ->[subseq from] serine hydrolase n=1 Tax=Emticicia sp. ODNR4P TaxID=2683257 RepID=UPI00141305B8 --kTLEKKLQVLVKDFQGVAGIYVKHLKKNTGV-AIQADTIFPTASMIKVPITIGLFNKIE -KGELDYHAILTYKDSLLYAGEDILGSFKDGEIALSKVAMLMITTSDNTASLWCQAMATG- -TAINEWLAANGFENTRVNSRTAGREAYRKLYGWGQTTPREMAELLVKIKKGEVISPAASE -RIYRNMVRIYW-DGEALSQIPPTVQVASKQGAVNQ-SRSEVFLVNAPSGD-YVVCVTTKN -QKDENNEGYQLLRNVSKIVWEHy ->[subseq from] Serine hydrolase n=1 Tax=Flectobacillus sp. BAB-3569 TaxID=1509483 RepID=A0A267TIN9_9BACT --kALEKKLQMLVKDFQGVAGIYVKHLKKNTGV-AIQADTIFPTASMIKVPITIGLFNKIE -KGELDYHAILTYKDSLLYAGEDILGSFKDGEIALSKVAMLMITTSDNTASLWCQAMATG- -TAINEWLAANGFENTRVNSRTAGRESYRKIYGWGQTTPREMAELLVKIRKGEVISPAASE -RIYRNMVRIYW-DGEALSQIPPTIQVASKQGAVNQ-SRSEVFLVNAPSGD-YVVCVTTKN -QKDENNEGYQLLRNVSKIVWEHy ->[subseq from] Serine hydrolase n=1 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A428Z679_KIBAR ------QRIRAVFQDAGTAGWLHAMPLGASREV-DVNADEPVVMASVYKLPLLVALCRQFD -AGRIDPLSTIRINPASCSPPTGIATFLDPITMSWRDLAASMMTVSDNAAADLILGEV-GL -DTVGKTLADLELTGTKIVGGAADVEAAYDPAYTSATTPRDMTRLLSLIWSDSVASAEQCA -FIRQLMGKQVW-LHRIRSGFPGDVRVSGKTGTIG-AVRNEVAVVEYAHETPIAVAIFTFA -ARSDLPAVDAAIGEAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium wangchenii TaxID=2541726 RepID=UPI0011C703DD -------------TAAGVDLGVAIEDLSDGRSL-FAGKQDRSTTASTIKMALAVTVMQQVE -DGMLTLDDIRTILPEERYEGSGVLKDGPFPQVSIGRMLDLMITVSDNTATNKLVDVVGGF -GPINATIEAAGIPRTDLHFGRKMFGGIVPPDGDLWLTPSGMNELLTRIYEAAFLSAASAE -HIIDLMLAQQV-KTKLGATVPAGV-LAHKTGENAE-VSHDVGLVLIPGQ-EITLSVFSTV -RPDVQAVANPFLQRIGTAVHD-- ->[subseq from] Beta-lactamase TEM-12 n=1 Tax=Synechococcus sp. MIT S9504 TaxID=1801628 RepID=A0A163Y7H8_9SYNE ----LSERWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD -AGRLSWNEPLQLNKTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ -EKLNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Flavihumibacter sp. R14 TaxID=2705549 RepID=A0A6B3PLK7_9BACT --kNLTGRLHDLVKGFQGEAGIYVKNLKTGKTA-FVNADTLFPTASMVKIPIMVGVFDEIE -KGNLNYNAELIYRDSLLYEGEDIIGSFKDGEIRLSKVQMLSITTSDNTGSLWLQKLV-GG -EKINNILQSMDFKHTRVNSRTPGRRPNWEVYGWGQTTPREMATLVEMIREGKVISPAASE -RMYRNLIRIYY-DGQALSQIPPYIQVASKSGAVDE-ARSEVVLVNAPHGD-YVFCITTKN -QKNQQNEGFRLIRNLSALLWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Dinghuibacter silviterrae TaxID=1539049 RepID=A0A4R8DI35_9BACT --rRLQKRVDSLTQGFHGDVGIYIYDPGRDRYA-ACQPDALFPTASIVKISILLGIMDKIR -TGALDYHQRLTYTDSLFFKGDDILSDFTPGSIELSKVMMLMLTISDNCASVWLQGLAGGG -TRINALLDSLGFSKTRVNSHTPGRSADWERYGWGQTTPREIVHIMDRIVRGEVFDPKSSA -MMLRLLGRQYW-DEEALSQIPAGVFAADKNGALDS-SRNEV--VYVHGRHPYIFSIFTKN -NTTQDNEAWALTRRLSALLWTYy ->[subseq from] Serine hydrolase n=1 Tax=Kitasatospora xanthocidica TaxID=83382 RepID=A0A372ZLK2_9ACTN ---AARTRIAAAFADAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA -AGRIDLTRQVDVPAAGRTPGSIGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL -DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGT -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATTLPAADAAIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Epidermidibacterium keratini TaxID=1891644 RepID=UPI0013194E72 --------IMEVFIDAGIEGAVHALDLDSGATV-EYAADRQFAMASLYKLPLLVALCRRFE -RGELDPTEAVTSRRDERTAPTGLSLLRDAVTMSLRDHAVSMISVSDNAAADILFARV-GH -DEIGRVLREAGCESTQVVGGTAETHAAYEPRLLGPTTARDQTRLLAAIWTGTLIGDAQGA -FVREALGSQVW-THRIRSGFPRGVRVNGKTGTLG-ALRHESAVVQYPNEPAYAVSVLTRA -ARADLPAADRAIGRAARVAVS-- ->[subseq from] serine hydrolase n=1 Tax=Peptostreptococcaceae bacterium TaxID=1904861 RepID=UPI0011DD730C -------KIISRLKDMEGDISFYYKNLVTQETI-KYNEEKEMLAASLIKLTVLVECFSQIK -QKVISKDEIFITKERDKVPSCGALNYMRENLVTLEDLYVLMIILSDNYATNILIDKL-GI -DNINMTIKDIGLKNTIINRKMFDSEKA-KLGLENYTSAKDMGDLLEMMYNKDLVDEKSSE -EMISILKNQRL-NGKIPQGVKPKVSIAHKTGEDTN-ITHDVGIVFAKDP--FIVCF-CGN -NV-NVPEYERLMQDITYDIY--- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537KLW1_9BACT --kKLRAMISSTIKQYNGEIGIYVKNLKSKRIV-AVNADTVFPTASIVKVPILIGVMDKTN -HGELFYDSSLTYKDSLLYEGEDILGSFKNNEILLKKIIMLMLTTSDNTASLWLQSLAGKG -TRINEILDSLHFKYTRVNSRTPGRESNRTIYGWGQTTPSEMGRLFEMIYYGQIFSPPVCE -RMMRCLGRNYWDENEAISQIPPTIEVFSKNGCVD-ASRSEVMLVNAPHN-PYVFCIFTKN -NKTHTNEAWTLARKISKLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. EAC657 TaxID=2024881 RepID=A0A2D8TW03_9SYNE ---ALSQRWKELAAQADLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD -AGRLVWNEPLTLTKTVVGGGAGWMASPIGTRFPTHEVATEMIRVSDNTATNLLIDRLGGK -EALNLRFNALGLSATTVNNWLPDLEGT------NTTSARDLAYSIALVDTGEALSIRSRD -LFRQVMGTSIT-NTLIPRGLMRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTEMIRKLTAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. CB0101 TaxID=232348 RepID=A0A4V1DI92_9SYNE ---AVSQKWAQLAARHDLQASGYLLVLDDGRFA-QLQPDRAMPAASSIKTPILLAGLEELD -AGKLRWNEPLALTKEVIGGGAGWMAKPVGTRFPFWEAATEMIRVSDNSATNLLIKRLGGK -VALNARFQAMGLTATVVNNWLPDLDGT------NTTSSLDLARSIALVDTGEMLSPRARD -LFRGVMGTSRT-NTLLPLGLLKGVTVLNKTGDIGI-AYADGGLIELPNGQRAVAAFMVKG -PFND-PRSTELIRAMAAEVA--- ->[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum terrychapinii TaxID=2290919 RepID=A0A398D6W6_9BACT --qDWQKQVRALLGNAQGEFGVYAA-TPSVSLF-EYQTSSIFPSASTIKVLIMAELLRQVE -AGTHALTEHP-VLPTAPTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIRLT-GM -DAVNQLAVDIGMTNTRLRRFMMDTES-IQQDIDNTTSPADMGRFFKLLACNELVSSKASA -TMKTILSHQQF-ADIMMLFLPEGIRAEHKTGGFP-GSVLDVGLVYGA-RDPLILCLMATQ -LAN-NGEGAIILGKVAAIAYT-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophaga sp. BN140078 TaxID=2607653 RepID=A0A5B2VY16_9BACT ---RLAALLRPLLAQHHGVAGIYVHHLKKDRYV-AINADTVFPTASTIKIPIMIGVFDKIA -NGELQYHQQLIYKDSLLYEEEDLLGSFKSGQLELAKVMMLMLTMSDNTASLWLQSLAGGG -LRINTWLEAHGFVNTRMNSRTPGREVNRSQYGWGQTSPREMARLMEMIYKGEVVSKTASE -RMYRNLTRNYW-DTEGLLQIPPYIRTASKNGAVD-ASRSEVIMVNAPHGD-YVYSIITKN -NQERNNEAWNLLRSVAGVIWNYy ->[subseq from] serine hydrolase n=1 Tax=Emergencia sp. 1XD21-50 TaxID=2304570 RepID=UPI001379D0FF -------KILQELAAMPGKVGFYYKNVVTGETL-GYNQQESFLPASVVKLPLMMAILLFRS -RGETDFDERITIRDDQKVPGCGAVQHIPGEVLEMGALAKMMITISDNTATNALLRHY-TV -PKVREAFHELGMIGTQFNREYYDYESE-NKGIQNYFVPEELGILLEKMYRRTLINEEASI -WLENVLRQQQI-NHKMGGYLPMDYPMAHKTGEEED-KTHDVGIVFAK--QPFIVCYASND -IE--IAVFEDFIRRTTKALAD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter gossypiicola TaxID=551995 RepID=A0A1H8SEC6_9SPHI --sKLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLGYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS -EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTMIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NTTPNNEAGLLIKKISALLWHYf ->[subseq from] Uncharacterized protein n=2 Tax=Lactobacillus harbinensis TaxID=304207 RepID=A0A510U2V6_9LACO ---EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAQ -NGDLNLADTYTVAGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIAYLGGL -DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN -QMMAIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIVQGDQH-VFVAVVMSQN -GHE-------------------- ->[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus harbinensis TaxID=304207 RepID=A0A5P2TUF4_9LACO ---EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAQ -NGDLNLADTYTVAGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIDYLGGL -DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN -QMMAIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIVQGDRH-VFVAVVMSQN -GHE-------------------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=UPI000BEF7D39 -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A317TIQ5_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGIIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINKTIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. HYN0043 TaxID=2305508 RepID=A0A494W7W7_9SPHI --nKLAVKLQDVVKGFHGQVGIYVQNLKTGKTV-EINADTLFPTASMIKVSIQCGVMDKIE -KGELQYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -QYINNWLDQNGFKVMRVNSRVAGREAVRKIYGWGVSTPREMCRLFTMIREGKAVSAAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSVITNH -NTTPNNEAGLLIKKVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces vinaceus TaxID=1960 RepID=A0A5J6J0U3_STRVI ----TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQHAA -AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMMAVSDNAAADLLLARV-GL -DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG -AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Olivibacter sitiensis TaxID=376470 RepID=UPI0003FD9D97 --kKLQSKLEQLCEGYEGTVGIYVYNLKTGKEA-AINADTIFPTASIVKVPILVGLFDKIA -KGDLSYHQPLLYRDSIKYGGSGLMQFFQDSVTDLSTLAALMISYSDNTTSLWCQALAGGG -ATINALMESYGLQATRVNSRTSGREDIWKIYGWGQTSPREMAQLLVKIRKGEIIDQAACE -RMYRLMSHIYY-DDYALSQIPPYIQTASKQGMVND-SRSELVMVNAPHGD-YVFYIATKD -NKDKDNAAWQLTRNLSALLWQYf ->[subseq from] serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=UPI000B8648B7 -------SIAEIFADAGATGFLHAREIGGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS -DAVNRVISDLGLRQTRLVGCCEDLFAAVHPIKTSHSTPRDVTTLLDALWTDTAAPAEACR -QARDIMAQQIW-PHRLSSGFPSGVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASERQPLVDASIGR--------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2CC25_STRVZ ---------------AGVTGRLHAVDIDTGADV-DFGADQPVVTASVHKLCLLVTLHQRAA -AGALDLTEQVECPADLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL -DAVNATTAALGLDRTHATHTFGELLAALDPARGNHSTPRDMTRLLAAVWRDEACAPPHGP -ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ASAILPAADAVIGTASRIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. SC4 TaxID=1793160 RepID=A0A135H494_9NOCA --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL -ESAERALSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Serine hydrolase n=4 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B2USB4_9ACTN ----ARHRIRDLFADAGVRGWLHVAELRRPAACvTVDPDEPVPVGSVYKVPLMVAFCRLTD -SGAIDPRQRVTLGAADRIPPTGVSLLQDEVTMSLRDLVVLMMTISDNTAAHVVQRWV-GT -TAVEAVCQSLGMPDTHIRGGAATTFEVYNPLRKASSTPADMARMLRAIWTDRAASAAGCA -FMRDVMGRQPW-SHRLASGFPDDVTVSGKTGTFGS-MRHEVGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAAARTAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Microgenomates group bacterium GW2011_GWC1_49_7 TaxID=1618530 RepID=A0A0G1VW95_9BACT ---TLKQKIQEAVANQWNNYSVYVVDYNAPFTV-GINETVIYDAASVNKIPILAALYVKAQ -NGEVDFDKTITPQPDDIQDTGSIRYDPPGTAYSIKTLARLMMQKSDNTAAYVLANHVVGL -NKIQTLANGWGLTQTDM--------------IKNTTTNRDMEILMKKIYDGKIVGTALTA -EMLAFLKDSDF-ENRLPALLPQDSTVYHKIGTID-GGVHDVGIVERGKT-RYYIGVFTDG -VA-DVEAAEKLIAKVSRMVFDY- ->[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000D718B1C -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLGKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Bacteroides sp. TaxID=162156 RepID=A0A3G2C899_9BACE ----LTDSISQIVSACPGEIGVAVI-VNNRDTV-KVNNKSVYPMMSVFKVHQALALCNDFD -NKGISLDTLVNINRDKLDPWSPMLKDYSGPVLTVRDLLRYTLTQSDNNASNLMFKDMVNV -AQTDSFIATIPRSSFQIAYTEEEMSADHNKAYSNYTSPLGAAMLMNRLFTEGLIDDEKQS -FIKNTLKECKTGVDRIAAPLKEGVVIAHKTGSA--------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Pedobacter nototheniae TaxID=2488994 RepID=UPI00103895DA --rKLQQKLDELVKGFNGEVGIYVKNLKTGKVA-SVNADTIFPTASMVKVPISCGIFNKIE -KGELDYHARLTYCDSLLYAGEDILGSFKDGEIELGKVLMLMITTSDNTASLWSQLMAGTG -TAINEVMASNGLQFTRVNSRTPGRREHQQKYGWGQTTPREMATLLTLIRDGKMINSAASE -RIYRNLIRIYW-DTEALSQIPPTVQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN -QKDTSNEGWTLIRNLSKTLWNYy ->[subseq from] DZANK-type domain-containing protein n=1 Tax=Lactobacillus harbinensis TaxID=304207 RepID=A0A5P8M8J7_9LACO ---EVQAAVNQTMGQIPGDNSVFVSASDELHLKhFVQNNRPQRAASIIKIFIMVTAFAKAQ -NGDLNLADTYTIAGADKVSGTGDMQNMPDGTLSYRQVMDHMMEKSDNMAANVMIDYLGGL -DVVNQEIKKLGFPDTVLERKMMDTD-ALAAGKDNMTSVQDLGDALTLINNGKLISKEADN -QMMTIMKNNQN-HEKLPAKITNATAIYNKTGEFQYGVENDAAIVQGDRH-VFVAVVMSQN -GHE-------------------- ->[subseq from] Beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain WH8103) TaxID=29410 RepID=A0A0H5PR08_SYNPZ -------RWRTIATQKDLQTSAYMLILDDGRFA-QMHADRPMPAASSIKTPILLAALQQVD -AGDLHWNEPLVLTKELVGGGAGWMASRPLGSFPTRVAATEMIRVSDNSATNLLIERVGGQ -QTINQRFDDLGLTATEVNNWLPDLDGT------NTTSAHDLSRSIALVDTGEALSLRSRD -LFREVMGSSVT-NTLLPTGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRALAAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus subterraneus TaxID=285983 RepID=A0A427TK48_9BACI --------------RCKGRASLFMEI--NGEII-EFNSNHVYQSASLIKLPILYAALRLVD -KGVLSLKKLVPIRETDEVGDTGVLQVLMVDQLSVQDLLALMIIVSDNTATNLVIDEI-GM -GEINSKIALLGMDQTVLKRKMLDFN-AIKNGNDNFTTARDTVACLKEGTAGSTLTNHSKG -IFQTLLKQQQL-KDKLRACLDPRIEAGNKTGELP-GVEHDCGFIFDEKT-QIHVAILIDQ -LN-DPEAGRTTIRQIGKHI---- ->[subseq from] serine hydrolase n=1 Tax=Sporotomaculum syntrophicum TaxID=182264 RepID=UPI00137B7C7F ---PLQRHITGYLAQQPGVYGLYFVDLESGQEF-GYHSQTIFHAASTFKIPMNLYLYRAAE -HGQIELSEQLLFTETHMEGGTGILKSHTPGGYSIAQLADYSILYSDNVATNILLTRL-GK -ENVKEYMRSLGGQVVD--------------NEQNITCPYDLALYMQEVIQ--LAKKPSGE -KLLDNLFDNLL-KDRIPAPLPPGIKVANKIGTWPTNTYNDAAYVVHPDK-PYILVITSEN -TP-GYSAAREVIRHLSELVYHY- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. KC216 TaxID=2530370 RepID=A0A4R4M2Y8_9ACTN ---DVAARIEAEFRSAGVTGFLHTVDMDTGREV-AVRAGAPVVLASVFKVPLLVTFHRQAA -EGLLEPSEQVTLPAEGRTTPTGVSGMLDEARLSLRDLTFLMITISDNAAADVVLERV-GR -DAVNATAAALGLRDTVVEVSGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPAGCA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -PLAVLPQADAVIGTAARIAVEH- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0S6M8_9BACT --eQVQKEFNEKTKDLSGIYGLYVISLSNGFFY-GVNDGEVFQAASLIKLPVMAAMYKEAE -NGNLNLDDKYTLKKSDKVAGSGSLYGKPAGYVTYRNLVELMGKQSDNTAFNIIRKLL-GD -EKINDLIRSTGMVDTSLEE--------------NETTPRDIGIFFEELMKGNIVSTNTRD -KILESLTDTIY-EDWLAAGIPEGTRVAHKYGREIH-VVNDAGIVFSDN--PFVIVIMSKG -VV--EREADSVFPELSKLVFD-- ->[subseq from] Uncharacterized protein n=1 Tax=Selenomonas ruminantium subsp. lactilytica (strain NBRC 103574 / TAM6421) TaxID=927704 RepID=I0GNK2_SELRL --eDLNANTARIIGDSKNQMSVYFLRPDREIEP-FLYNQRQMSPASIIKLFVMAKTMQDIH -DGKLSLDDRITIRKNDVVGGAGVTTWYDGQQRTIRQLLTVMITDSDNTATNILIDKL-GM -KEINRYIAQSGYSDTMLAHKMMLSN----GGRKNLSSVRDLGHLLTKLYYHQLVGPEEDE -FMLTILKQQHD-KECLGSALT-GYTVAHKTGEVT-GVYADGGIFFGAQED-FILVILNNG -NEG-------------------- ->[subseq from] Serine hydrolase n=3 Tax=Streptomyces TaxID=1883 RepID=A0A3B7RHP9_STRFR ----AQRAIRGMFADAGVRGWLHVAELHREARV-TVDPDEPVPVGSVYKVPLMAAFCRLAD -AGALDPRQPVTLGPDERMPRTGISILRDPITVSLRDLVVLMMSVSDNTSADAVLRHV-GP -AAVEELCRDLGLPDTHILGGAATTFEVYNPLSKASSTPSDMARLLRAIWTDGAASAESCA -FMRETMGQQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGGVYTAVVFTQA -ARADLPRADAVIGTAARAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus opacus PD630 TaxID=543736 RepID=W8H8W8_RHOOP --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL -ESVERALSELGMTSTRIIGGTADAHRAYDPSYASATTPRELTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter kameinonensis TaxID=452286 RepID=UPI000EF773A2 ---KLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDILGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS -EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTLIREGKAVSAAASE -RMYRNMGRIYW-DEHALSQIPPYVHAISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NKTPNNEAGLLIKKVSALLWHYf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=A0A0U5ES95_9PROT ----LAQSISKTVKAQPGHFAVYAALSGHSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPQDTVTIHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD -LP-DEQAGIKVLNTLSHQTYTYf ->[subseq from] Uncharacterized protein n=1 Tax=Ruminococcaceae bacterium CPB6 TaxID=1572656 RepID=A0A1W6WF51_9FIRM --eTLQKKTAALIEDAAANVSVLVQDIAGRQPLlAFGEQRRLVSASTIKTQILLTVLDEVR -QGKRNLQDMVSIAPADILPDSTAFDRPVA-AASLEELLYWMVCISDNTATNLMIRLV-GM -DAVNRYSSELHLTDTSLQRKMLDHNAV-RQGRNNYTSPRDMLCTYRALAQKTILTPQLCS -YALSLLSRQQD-KTVAFRYIWEPLQAAHKTGELR-GLDHDTGLLFLNGH-TYFFGLFATD -GS-SNRENQQLLGRLFRMLVDY- ->[subseq from] Serine hydrolase n=1 Tax=Arachidicoccus ginsenosidivorans TaxID=496057 RepID=A0A5B8VNN4_9BACT --kHLQSALTALLRGFHGTAGVYVENLKTGSVA-AVNADTIFPTASIIKVPILIGIFNKIK -TGDLSYNQTLIYDTSRTRGGSGLMQFFKDSSTSLDVLISLMISYSDNVAALWCQQLAGGG -VQINQLLENMGFKDTRVNSRTPGREKAYSNYGWGQTTPREMATILKLIREQKAVDAASSD -CMYRQMSHIFY-DGYALSQIPPYIQTASKQGMVND-SRSELVMVNAPHGD-YVFYIATKN -NKEKDAEPWELARQVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329UKU0_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EIGADEKFETASTIKAFILAALYLQVS -RGKASLEEEITYEESQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFADTVLHNPLH-FD---RYDDLGTTTPRDYAALFAQVAKGTLVSKEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus horikoshii TaxID=79883 RepID=A0A5D4SZG6_9BACI ---ELKERVQAVVDSTAGHVSFMLED-NCGQLL-EKDCDVPKKAASLIKIPLLMAALKQVE -AGNINLSDRMNIESESRVGGAGVIQYLDQDTFTLCDFLTLMITVSDNSATNKVIDLI-GI -DSVNKFCTEQGLSNTILERKMMDVKAS-DAGLENRTCARDIVACLKILLDSNVLNVESKQ -LMMSMLRGQQL-LDKLPFFMNNTVQVANKTGELP-GVEHDCGIVTFGEK-SLIMAVLVDN -LIE-NPSGKRAIQKIGRIIE--- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W6AUW2_9CHLR ---NLQKLLEQSVAGLAGDWALAVKKLDTGQMA-MVRGNERFVAASLYKLDVLLAVASLHA -QGKLNYDDTITILDDDIEDYANGDPGDPGTVLTVQRTAELMIDESNNTAAAMLIRTVGGQ -NAVNSTLQDYGLGHTIYDPNN-----------DNLTSSGDMMRYFEMLYSARLVDADESK -WMLDILLRQEL-NFLIPANLPDNVPVAHKTGNLPN-LMHDAGIVYSPGG-PYAIVVLAQN -LD-SEDTARAMTPQISQAVYDYf ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium AC-409-J13_OGT_754m TaxID=2587834 RepID=A0A5N8YIQ0_9CHLR ---NLDRELGFMAKSFPGIAGIAVKPLIGNAFI-SINGDEIFPTASTIKIHVLTQLLRKAE -KGVFNLNDVLDIRKHPLVQGSLITSSLEGPVLSILNLAILMILVSDNLATNICIDLA-GI -AETNTMIRSLGLPKTTLSRKMQDKA-SIRKNNENISTPNECITFLELLKQGQP-SPTVAE -RCISILTKPKTG--PLNRAIP-NVPISNKPGTMGR-VACDVGIVNLDNY-PYYIAIMTKF -GMLEALEQTQFLVDVAKTVHQ-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522SKK6_9BACT --kKLTMELQKLVNNFRGTAGVYVYDLKTHREA-AINADTLFPTASIIKVPILVGIFKKIQ -EGELNYHQPLLYHDSLAHGGSGIMQYFKDSTTNVSVAVTLMISHSDNTAAHWCQALAGGG -AAINSWLADRGFQFTRVNSQTPGREKADDMYGWGQTTPREMAHLLCLIRENKIITPAACE -RMYRDMTHIFW-DDYALSQIPPYVQTASKQGMVD-ASRSELVMVNAPHGD-YVFYVATKN -NKKPDNEAWQFARNVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Cytophagales bacterium TaxID=2053541 RepID=A0A521GHJ6_9BACT --kTLERDLRALLTGFRGDVGVYVRNLRTGATA-TINADTTFPTASTVKIPIQCGLFDKIN -KGEWKYGQEIVYRDSLYYDDGLIGQLKDSAKIPLSEVVMLMETTSDNTASLWCQAMAGGG -ASINAWLDANGFAKTRVNSRTPGRREFQKQHGWGQTTPRELAELLVYIREGKAVSPDASD -RMYRNLCRQYW-DNDGLSQLPPEVKVGTKNGAVNR-SRSEVVLVHAPHGE-YVYCLMTKN -QAERNNEGFELLRRVGALLWKHf ->[subseq from] Serine hydrolase n=1 Tax=Sphingobacteriales bacterium 46-32 TaxID=1895839 RepID=A0A1M3FXT9_9SPHI --qQLLHKIRQAVQGFNGDVGVYVKNLRTGRVT-QINADTHFPTASIVKVPIMLGIMDKIQ -RGELHYDSAHVYRDSLLYEGEDILGSFKDGEILLKKIIMLMLTTSDNTASLWLQKLAGTG -TRINEILDSAGLRQTRVNSRTPGREPNRSIYGWGQTTPAEIARLFELIYTNKLYTPAACD -RIMRCLGRNYWDEAEAISQIPPTIEVFSKNGCVN-AARSEVLLVNAPHN-PYIFCIFTKN -NKQRSNEAWTLARKLSALVYQHy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces asterosporus TaxID=285570 RepID=A0A514JRN2_9ACTN ----------------------------DGREV-AVDADTPVVIASIFKVLLALEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVQLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPRDITRLLRLVWTDRAGPPEACA -LVRDLMHRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAIAVFART -RDASRPTVDAAIGRAAGMA---- ->[subseq from] serine hydrolase n=1 Tax=Echinicola rosea TaxID=1807691 RepID=UPI0010CA7869 --kKLTAGLNALMEEFQGTAGVYVEHLPSGKYA-AINADTIFPTASIVKVPILIGIFDKIE -KGELTYHEELVYRDSIKYGGSGLMQFFEDSTTDLSTLLALMITYSDNTTSLWSQALAGGG -ETINPILEKNGMEFTRVNSRTAGRTRDWEKYGWGQTTPREMATLLKKIRKGQVVSKAASE -RMYRLMTNVYY-DDYALSQIPPYIQTASKQGMVN-ASRSELVMVNAPHGD-YVFYIATKK -NQEPDNAAWVLARKVSALLWDYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ865 TaxID=1288081 RepID=UPI0004210501 -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRIDLTTVVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMAALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Heliobacterium gestii TaxID=2699 RepID=UPI00136CB032 ----LKQQIQNYLNTRPGQVNLFVQDVTTGAKM-DIGGDEIHRTASTHKVPTVMYLYRLAA -QGKVDLDAKLTYTSQYYRQGTGILQTKPYGGYTLRELGRLSIVYSDNVAWAMLLDYL-GR -DNVNTFMRSLGGNVTGSDAKGYF-----------ITTPRDMGKYLGALLLFRDAQPQLGG -EIFHAMENTIF-NDRIPAKLPTGTVVAHKIGSLDD-SIHDVGIIFANNR-PFILSIYSKN -GWE--AASTDTLAQVSKMIYDY- ->[subseq from] serine hydrolase n=1 Tax=Bacillus jeotgali TaxID=129985 RepID=UPI000C84C34B ----LRERLLKELAGCKGRASLFLEI--EGEII-EVNSQQVYQSASLIKLPILIEALRQIE -EGKLQKDRLVTIRESDKIGDTGVLQAMNVKQLPVEDLLSLMIIVSDNSATNLLIDLI-GI -NSINSTLSRVGMKNSILQRKMLDFD-AIQSGHDNFTSAADIALCLKEAVAGGALNKQSKN -TFFSFLLQQQF-KEKLPFYLDALLKIGNKTGELP-GVEHDCGIITYGKK-QAFIVVLIDG -LSEP-DSGKTIIRQIGKHI---- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus opacus (strain B4) TaxID=632772 RepID=C1AR65_RHOOB ---SAEKRIRDVFADAGCTGWLHARRVGTPAEV-GVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSDLGLTNTRIIGGTADAHHAYDPSYASATTPREMTSLLDAIWAGRAVPGAQGG -FVRQVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. S4.7 TaxID=2705439 RepID=A0A6C0PXW4_9ACTN -----RDRIRAAFADAGVTGWLHAADIDSGAQI-DVGADRSVVTASVHKLCLLVALHQHAE -TGRLDLTDQTECPGDGRTAGPTGLSAMLDPALSLRDAAYLMMAVSDNTAADLLLERV-GL -DAVNGTTQRLGLTRTHAVQTFRDFIAALDPARTNHSTPRDMTRLLGAIWRDEACTPEHGA -AVRRLLALQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Apibacter sp. HY041 TaxID=2500547 RepID=UPI000FE37E51 ---EFNDSIYHLIKNKKLDIGISVRDNTGDEIV-SYNQNKKYKLYSVSKYFLGLYILDQVD -KGNLNLNQPVIFSKKDLKPYSPLRDSIPGTTLTLKESIKYLIEDSDNNVFDKLIDISGGF -QRLNLFVHQIVPNKFAINAGYSDSETL---FQSNVITPSLTTEILYKMENRQIISDESLN -LLKFYMQHSVN-NKRIQGLLQTKTKSFHKSGTSGRKATNDIGIVELQDEQSFSIAVFISN -SHEDDATNEYIIAKLADIIYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces calvus TaxID=67282 RepID=UPI001153BAF6 ----------------------------DGREV-AVDADTPVVIASIFKVLLALEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVQLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPRDITRLLRLVWTDRAGPPEACA -LVRDLMHRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAIAVFART -RDASRPTVDAAIGRAAGMA---- ->[subseq from] serine hydrolase n=1 Tax=Rudanella sp. HX-22-17 TaxID=2614655 RepID=UPI0012617294 ----LERDLRAMLSAFRGDVGVYVRNLRTGETV-AINADTLFPTASTIKIPIQCGLFDKIH -RGELKYGAELVYKDSLHYDDGIVGQLKDGARLPLSQVVMLMETTSDNTASLWCQAMAGGG -AAINAWLNANGFTQTRVNSRTPGRAAFQKQYGWGQTTPRELAELLAYIRAGRAVSPDASD -RMYRNLCRQYWDGDGL-SQLPPEVKVASKNGAVNR-SRSEVVLVHAPHGE-YVYCLMTKN -AQDENNEGFALLRAVGARLWKHf ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MJ1a TaxID=2599294 RepID=A0A563U959_9SPHI ---KLTSQLQGLLKNFNGTAGVYVHNLKTGKTA-AINADTLFPTASMIKVSILNGVMDKIE -KGELKYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG -EYINNWLAANGFKVMRVNSRTPGREAMRNIYGWGVTTPYEMCKLFTLVRDGKAVSPAASE -RMYRTLNRIYW-DEHALSQIPPYVQAISKQGAVD-ASRSETVLVNAPHGD-YVFSIITKN -NKTPENEAGILIKNVSALLWRYf ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=UPI0011D21748 ---SHAKELNDLEKKYNAHIGVYALDTKSGKEV-KFNSDKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKAIIEASMTDSDNTANNKIIKEIGGI -KKVKQRLKELGDKVTNPVRYEIELN----------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase TEM n=2 Tax=Lysinibacillus sphaericus TaxID=1421 RepID=A0A3P6LA62_LYSSH ---QLKEELHRIANDVAGDVSIYATT--SDGVI-AIREDEVKRSASILKVPVAMACLEAAD -RGEIDLDTVLEIEA--PVGGSGVLAYMSDMEITLRNALTLSIIVSDNTAANLVIEHV-GF -ERIQSFFNQVGTTHSQLTRKFMDYD-ALAQGLENVATARDMVRFLACLDPSEILSLTSKQ -QLKTIMRDQQL-IDKLPAFQPETLIIGNKTGTLP-GVEHDIAYFESGEK-RVDIAVLTTN -WEYN-HDGQQTLAQIGKAIIQY- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RZX5_9CHLR --nALRDSLDGAVAEFDGHAAVVVSGVDTNFRY-AKNDDAVFPSASLYKLEVMVEAYRQVT -AGRISLDDTVTVVWDDMSV-DP-SDTLPGTTLSVRDAVERMITLSDNGPAHALMRLL-DP -HNVNATTLSVGLKDTRINAALPPDE---QLSEDNTTSARDMERLFAGLATGKIVSPDASA -EMLATLFRQQI-NDRLPTGLPADAALAHKTGDLI-GVSHDAGLLLTPFG-PRVVVVLTSD -FS-DYDDVARLMARVATAAYT-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcales bacterium UBA10510 TaxID=2055795 RepID=A0A354AZE8_9CYAN ---DLSKRWAQLAAQSEFQASAFLLVLDDGRYA-ALQADLAMPAASSIKNPILLAALQDLD -ASKLRWNESLPLTAEVQAGGAGWMAKPLGTSFPVYETATEMIRVSDNSATNLLIKRLGGK -ELLNARFQTMGLNATAVNTWLPDLKGT------NTSSSRDLARSIALVDIGQALSPRSRD -LFREIMSQSHT-NTLIPLGLLQGVRVYNKTGDIGI-AYADAALIELPNGHRAVAAFMVKG -PFND-PRSANLIRAMAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3N104_9PSEU --------------KAGVRGFLHARHLGSAAEV-SLDADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRARAADRLGGTGMAGCADDVEMSLRDAALAALSVSDNTAADLLFDRV-GV -GNVRSLMTELGLTSTRIIGAPKDVLRALDPLRTTASTPREMTRLLELIWRDEAGPPEACR -QVRDLLGFQIN-WYRVAAAFDDEVAYAGKTGTLPQ-IRNEIGVATYPDGEQYAIAVFTTG -RYGRRPDIDQAIGAAARSAVDQ- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3N5MR70_9BACT ---NLDTRIRAEISRFEGKVSLFAKNLDTGTTY-AFGADDMVRTASTIKIPVLVEAFAQVA -EGRVRWADKVILKDAKKISGSGVLQELSDGLLTLRDAVTLMIVLSDNTATNLALDVL-TT -DAVNARISGLGLKHTFLLRKVGGGGVKAGEDPAGVTTPREMVFLLEKLERGEVISPAASA -EMIKLLKRTQ-GHEGLGRTLQ-GVEMATKPGALDR-LRSEVGIIYTKRG-RIAVAITCDD -MPK-------------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Rhizobiales bacterium GAS113 TaxID=1884352 RepID=A0A1H1H3K2_9RHIZ ----ASDIVAALRDRDGIDVGFSAIHLASGQCL-EINASSLFPTASVFKVPVMVEVFRQAR -AGIFAMSDRLTLATCHKTLTSGVLVTLDDGLPTIGDLVMLMTIVSDNTATKLLLDLV-GM -DKVNAATAGYGLHDIHVAIDVHEMFLTFSRERDNTASAADMARLMAMIAAGEVVDAEACG -SMVAIMKEQQY-SERVPRYLPFG-SVANKTGTMR-GVRNDSGIMRRGEGDDIAYTVFTFD -PTPLAAGNSRFLAE--------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus vietnamensis TaxID=218284 RepID=A0A0P6VYI1_9BACI -------------------------------SF-HINGDSTYSAASLIKIPILLEGFRQAQ -EGKISLSDRVTIPKEGRVGGAGVLVSLSDHLLTVEDLLTLMIIVSDNTASNLLIERL-GS -IAIQDLCDTLQLKQTMLRRKLMDFEA-VEQGLNNYTSALDIISCLKVLDIGTEYSPTSRK -KMLHILHQQQF-DTKLPSRMDRGVYIANKTGELP-GVEHDSAIIKFREKT-AYIAVLIDE -LGQN-EPGKDTIAQIGKLMS--- ->[subseq from] Uncharacterized protein n=1 Tax=Anaerolineaceae bacterium TaxID=2024896 RepID=A0A2E0ZEE4_9CHLR ----LLEQIREICEAFDGRIGLSATNLQTEETV-GHQAEEVFPTASVIKLPVLLTLMQQVE -DGLYSLDDPLMLRRGDKIGGSGLLQYLSPGLMSLRDWALLMMSISDNLATNVLIDHV-GL -EQVQQWLNDNGYPNVKLRRKIDFNILNKDQNELGTATPAGLTRMIMAVFQQRHLTPAACT -EMLRMMN--KVGYDRVGRYLPKKLQLAGKTGSLK-GMRAQTAVVYPEQNNGFALTIMNEG -NPQPDAPGVLVIGRLTRLIYDAw ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02056 TaxID=1703924 RepID=A0A1Q4VIE1_9ACTN --------------DAGVTGRLHARDLDTGAEI-GLGADTAVSTASVHKLCLLVTLYREAA -AGRIDLTRQVDVPAAGRTPGSTGLGAMLDDALSLRDLAYLTAAVSDNTAADTLWDRI-GL -DTVNRTMADLGLTRTVAVHKLRDLIAVLDPAFTNHSTPRDMTTLLAALWHGDACPGDHGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATTLPAADAAIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Acetobacter farinalis TaxID=1260984 RepID=UPI00140C2978 --eALQQSIARTVQAAPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYAAFA -KGQLSPEETITVHNHSLV-GSGTFYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPVRSVVKAQGLNGIFFGRMIEDFDAN-DQGIRNRVSARGLGGFLQKLDSGRIVGKAQSQ -SMVQIMLGQTF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAALVTLPDGTRYILVLLTSD -LP-DEQAGIKVLNGLSHQVYGYy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8QCX3_9ACTN -----RDRIRAAFADAGVTGWLHAADIDSGAQI-DVGADRSVVTASVHKLCLLVALHQHAE -TGRLNLTDQTECPGEGRTTGPTGLSAMLDPALSLRDAAYLMMAVSDNTAADLLLERV-GL -DAVNGTTERLGLTRTHAVQTFREFIAALDPARTNHSTPRDMTRLLGAIWRDEACTPEHGA -AVRRLLALQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura montaniterrae TaxID=1803903 RepID=UPI00124D540E ----TAVRIEAAFRDAGVTGFLHAADIDTGREV-AAGADAPVVLASVFKVPLLVAFHRRAA -EGLLDPTEQVTLPAGDRTSPTGVSALLDDVRMSLRDLACLMITVSDNAAADALLDRV-GL -DAVNAAAAALGLRETVVTGGGRQLFDALDPSRTSRSTPRDMTRLLAAIWRDEAAPPDGCA -AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLLT-VRNEVGVVEYPDGGRYAVAVFTRS -LLAVLPQADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNS335 TaxID=1169160 RepID=UPI00035CCC1A -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRIDLTTAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGAQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium ADurb.Bin219 TaxID=1852933 RepID=A0A1V5VRD0_9BACT -----KKEIADLVSPLKGNYGVFVQDLASGKSY-GYNEDQVFDSASLNKLPLLLALYREAE -AGNLDLETKYSLRVGDKRPGAGSLQYPVGYSLTYRQMAELMGKQSDNTAFNVVSRIL-GE -EKVQRLIDDLGLKKTSFVDWE--------------TTPADIGLFFYKLYTQNLLIRDDRD -ELLSFLTETIW-EDRIPTGIPNGIRVAHKVGSEI-GVVSDAGIVFAK--KPFILAILSRG -VL--EKEAKEVLPKIAELVYKQf ->[subseq from] Serine hydrolase n=1 Tax=Kribbella pittospori TaxID=722689 RepID=A0A4V2M886_9ACTN -----SARIRAVFEDAGVRGWLHAVALDSPDSTvEVDADTVVPMASVYKVPLLAGFCRLVD -LGEVDPRQQLTLDPSTRTAPTGVSILADPVTMSLRDLAVSMMTVSDNASADALLDVV-GL -QRLAELLESFGLKRTWVRRGTAGNLRVYEAANGSASSPRDLTTLLRRLWTGELLSEEQTA -FVRATMHRQLF-MHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Microcella alkaliphila TaxID=279828 RepID=A0A4Q7TZ77_9MICO ----LQQTVDALEERWGLTAFVHGMALDGDADV-GVRADEPVVAASVFKLPVLVEACRQIA -AGDIDPTRRFDLAPDDFAVLGPTGIAVFADPLSFRDLCLSMMSVSDNRATDVVMDAV-GL -ERVNATMRALGLGSTVLEGDCAALFAALDPRRTNRTTPREASQLLARLWTDRGIDPSACA -EARRILGLQVW-SNRLRAGFPDSVRVSGKTGTLLT-VRNEVGVVEHPDGGRCAVSVFLRL -PAADVPHFDHAIGEIAAAAVA-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces roseus TaxID=66430 RepID=A0A0J6XFD0_9ACTN ---DTRRRIAAAFTEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQQAA -AGLLDLTEQVECPPADRSAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARL-GL -DAVNGATARLGLTRTRAVHSFRSLFAALDPARSNRSTPRDMTRLLTAVWRDEACTPEHGV -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. CC9616 TaxID=110663 RepID=UPI00048D7073 ---ALSEKWKQLAAQKDLKTSAFMLILDDGRFA-QLEAERPMPAASSIKTPILLASLELID -NGDLHWNEPLILTKELIGGGAGWMAKPVGSRFPTYEVATEMIRVSDNSATNLLIERVGGQ -AAVNARFQALGLPATEVNNWLPDLDGT------NTTSARDLSRSIALVDSGETLSPRSRD -LFREVMSTSVT-DTLLPTGLLQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG -PFN-DPRSTDMIRALAKAMA--- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2E8HKH2_9BACT ------DEIEEIAEGFQGRFGFYLEDLASGATH-ARLEEERFPTASMCKIPVMVELYRQVA -GGGLSLGERRRLVGEISRHGSGTLSLMWDHPLTLADYCRMMMAVSDNMATDFLMSVV-GL -GNIDRTMDELGFSNVRTPMTIGRFHYYSDSIQNNVTSPTEMALLVKRIHLGEIVSADASA -AMIALMKGCRD-RRMMARYVDPEIEVAQKTGSSGR-IKGNTGMVYLPSG-PLLISAYGLA -AA-DDVDGGEAIARISRLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ279 TaxID=2035251 RepID=A0A2G7E4K4_9ACTN -----ERTLRALFDDAGVRGWLHVAELRRTARV-TVDADETVLMGSVYKVPLTVAYCRQVD -AGVLDPRQRVTLPPQDRLPPTGISHLRDEVTMSLRDLVVMMLSISDNAAADAVLRQV-GS -TAVDDTCRALGLVRTRLNDGAAGTLAVYDPAWATATTPAEMARLLRAVWLDEAASPDSCA -FVRRSMGLQPF-QHRLAAGFPDEVAVYGKTGTFG-AMRHEAGVVELADGRAYTAVVFTQA -ARADLPRADAVIGAAARTAVEH- ->[subseq from] Uncharacterized protein n=1 Tax=Microbacterium sp. Root61 TaxID=1736570 RepID=A0A0T2L253_9MICO ----ALERVRQLSAQTGIGVFAHAIDIDSGRGL-GVQSDSAVVTASVFKVPILLEYARQSD -AGELDAARSLIVDPATVTLGPTGLSVFSDPTWSIRDIATSMITVSDNAATDILLELV-GR -DRVNETMSAFGLPGTFLEGDCQALFEANTPEVTNRTTPRESTRLLQLLWTDAAGTPAACA -EARRILGLQVW-PHRLTSGFPGEVALSGKTGTIGV-VRNEIGVVEYPDGARYAVAVFLRI -PRSRAPEADALIGAVGRTLVD-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. XXST-01 TaxID=2492960 RepID=A0A431W3F2_9BACI ----LVDSIRKQIELCPGRISLWVEI--GDWSF-EHDSERVYSSASLIKVPILIEVLRQNE -KGLFSLADSLQIGEGQRVGGSGVIQALEQSFWTIKDLMTLMITVSDNTATNMLIELL-GM -DAVNESMELMGLKKTKLQRNMMDFT-ALQQGTDNQTCASDMIRCLKVIDECGFLTEKSCH -EAKKILQHQQF-HKILELLDSDKGYMGSKSGSLP-GVEHDCAIINYEGKT-AYVAILIDQ -IP-DGKSGTLSMKEIGKAVFD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Edaphobacter dinghuensis TaxID=1560005 RepID=A0A495BQI2_9BACT --eALQREVAAIAGAHQGQVAMYATQLNTGRIV-ALHADEPVQTASVIKLTILFEAMEQVR -AGKAHWDEKLTLAKGDAVSGSGLLTFLDAPVLTLKDVLTLMVIMSDNTATNMAIDRF-GI -DAVNQRIGWMGLKDTHLYKKVMKMPADQPKFGLGKTTPREMAKVMERIGRCQLAGRGEEA -QALQ-MLRNQFYRDTVPRYLEEGSGIASKTGSLNT-VRNDVAIVAGKSG-PMILSIFTYD -DQDQDNQAEVTIAKLAKAIVEVw ->[subseq from] Serine hydrolase n=1 Tax=Ignavibacteria bacterium RIFCSPLOWO2_12_FULL_56_21 TaxID=1798438 RepID=A0A1G0SG34_9BACT ---DLQLQLEDAARSVRGTVGIYVRNLETGETA-AVNADTLFPTASMIKVPILCGVFDKIV -SGDLEYDSAYVYRDSLLYAGVDILGSFRDSAITLSKLVMLMIATSDNTASLWLQSMCGTG -TAINDWLERNGFHATRVNSRTPGREELRKHYGWGMTTPREMAELLAYIRVGKAVRPDAGE -EMYRVLSNIYWSD-GALSQIPPTINAASKQGAVDE-SRSEVVLVNAPHGD-FVFCVITKD -LQKRENEASTLIRKVSSMLWNYf ->[subseq from] serine hydrolase n=1 Tax=Halorussus amylolyticus TaxID=1126242 RepID=UPI00104EFB1D ---DLVAHLDSYAEKLDGRLGVFLRGPDDFDVVyRANADETFTSASVIKIAILYALYEKYD -GNLAELDRPREIAPENRVAGSGLFHLLSDPRPSLDDLARAMISISDNAATNELIDEV-GM -ERVEDAASRIGMDDTRLRRKMMATLGWPEGEPANATTPADCARFFADLVHEATLSSDAYD -RMTVPLAEQKY-TGSFPRYLPFETTVAHKTGSVPS-AALDAGYVSISDSTPLVFAVFADE -LEAG-ADGSDAIAEIGDGVYE-- ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma linguale (strain ATCC 33905 / DSM 74 / LMG 10896) TaxID=504472 RepID=D2QMG0_SPILD ----LERKLQTALKGFRGDVGVYVHNLKTGVTV-AIKADTLFPTASTIKIPIQCGLFDKIH -KGELTYGQTLIYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTASLWCQALAGGG -TAINTWLESNGFRKTRVNSRTPGREADRTRYGWGQTTPREMADLMTYIRQGRAVSPDASE -EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-SRSEVVLVHAPHGD-YVYCVMTKN -QQERTNEGFALLRNVGTLLWQHf ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4R5BPN4_9PSEU ----AAQRIREVLADAGAQGWVHAVRLGGGDHElGFGADELVVTASVYKLPLLVALARAFD -AGTLDPREAIRLDPGSCTPPTGVSTFQDPVRMSWRDLAASMIAVSDNAAADVILGAI-GL -DALAAALADLGLERTRVVGGTADAHAAYDPSYASATTPREMTRLMELIWADAVASPQQCA -FVRRLLGQQAW-MHRVRAGFPQGVRVSGKTGTIG-AVRNEVSVVEFDGEAPVAVALFTLA -ARPSLPRVDAAIAECARIAV--- ->[subseq from] Possible beta-lactamase family protein n=2 Tax=Synechococcus sp. (strain WH8102) TaxID=84588 RepID=Q7U8A4_SYNPX -------RWRTIATQKDLQTSAYMLILDDGRFA-QMHADRPMPAASSIKTPILLAALQQVD -AGDLHWNEPLVLTKELVGGGAGWMASRPLGSFPTRVAATEMIRVSDNSATNLLIERVGGQ -QTINQRFDDLGLRATEVNNWLPDLDGT------NTTSAHDLSRSIALVDTGEALSLRSRD -LFREVMGSSVT-NTLLPTGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRALAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces roseus TaxID=66430 RepID=UPI000D1A60B8 ---DTRRRIAAAFTEAGVSGRLHAVDIDSGTEI-DAGADHPVVTASVHKLCLLVALHQQAA -AGLLDLTEQVECPPADRSAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARL-GL -DAVNGATARLGLTRTRAVHSFRSLFAALDPARSNRSTPRDMTRLLTAVWRDEACTPEHGV -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus sp. OK270 TaxID=1882814 RepID=A0A285DZ56_9NOCA ---------------------------DDEDAV-SVGADELVVTASVYKLPLLVALCRAFD -VGSLSPTATVRINPADCTPPTGVSTFRDPVVMSWRDLALSMMTVSDNAAADLILGRV-GL -DGIDRVLAELGLLRTRIVGGTADIHRAYDPAFTSATTPREMTSLLDAIWTDGVVSADQGQ -FIREVMAGQIW-PHRIRSGFPAGVTVAGKTGTIG-AIRNEVAVVGFPGETPVAVAIFTRA -ARADLPVVDRAIGRAAHIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. FC4001 TaxID=1408313 RepID=UPI0009E079E9 ---------AQVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH -DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTIAQLIQLMVVESDNTATNMLIDKL-GM -ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEKEDA -FMLDILEQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS -NE--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces nanshensis TaxID=518642 RepID=A0A1E7LYS5_9ACTN -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPHHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GT -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGSQPW-THRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Uncharacterized protein n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A1F5ZWX2_9BACT ---ELKNKIEKELEKTTGTYSIYFYDLTTGDNF-GINEEMIMMAASINKIPILAAVYYSAG -KGIIDLDKIIVPQVTDIQDTGTIRYNKPGTAYSIKTLARLMMEKSDNTAAYLLASVIVGL -DEVQKMVEGWGMTQTDMK--------------SNKTSVKDIFNISKKMYQGEITTPEYTR -EMIDFMDDSDF-EDRIPKGVPLSITVYHKTGDEVR-TVHDAGIIVLPDR-PYYLGVMTTD -IEN-EEETKNKIARISQIVF--- ->[subseq from] Serine hydrolase n=1 Tax=Methanomassiliicoccus sp. TaxID=2528041 RepID=A0A524IY86_9EURY ---RLKSELLKMAKDVKGHLGLFIKHVESGREI-TVDADKTFPLASVFKLGVMVETFRQIE -EGSISLEERIELEPRHYCIGEGVMQYLSPGLPTVGDLLSLMIIATDNTASEMLWKRI-GI -QRVNMLMRELGLAKTSIY------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces albidochromogenes TaxID=329524 RepID=UPI00110F70E8 ----VHTVLASTFTQAGVEGYVHARDLDTGEEL-GHGADSQVVLASVFKIPIALEYARQAA -AGELDPARRHTVTAAYRAGGSATDGCAYDVEMSARDLAFMMMTISDNAATDLLLDVV-GP -DRVRATLDGLGFPGFGFSSSAA-LDDACAPGSSPSSTPREVTALLAAIWRDEAGPASACA -EVRDIMGQQVW-QHRLVSGFPAGVRLAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT -STTRQPLADRAIGRAARLAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Flavobacterium kingsejongi TaxID=1678728 RepID=A0A2S1LJG3_9FLAO ------------------------------------------------------------- ----------------------------------LDQFLKYTVSDSDNNGCDILLNLIGGT -ETVQKFINKQGINDFTIKVNEQEMKT-WEDLYKNATTPLATTELLEKFYKGKVLKKKTTA -YLYQKMEETTRGTNWMKAGLPAGTELAHRTGFSATDAMNDVGIVKLPNGKHFIISIYIKN -TTEPREDFEKIMAEITKLTWDYy ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus dakarensis TaxID=1917889 RepID=UPI000B42F526 -----------------------LIKTKSGDIA--INACESIRAASMIKIPILIEAYRQIE -RNLLDPETSVDIESEKKAGGAGVINYLTNVNYSYQNLLELMIIVSDNTAANLLLEKI-GV -QHVNKFAAEIGLYHTKIGRKFMDQK-AIEKGRDNYTCAYDMVQLLSLIAENKIVNDDSRK -QMLRILYYQQF-KQKLPAYLHDGIDFFHKTGELP-GIEHDAAIISNKGD-TIYAAILTQN -WV-NNGIGRDYIADIGRLLINY- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadaceae bacterium TaxID=2026741 RepID=A0A2E0DR42_9BACT --dSLQSRVAARLDRLDAISSIYAKHIPTGREI-AVRADHPMNTLSVIKIPVMVKAFQDNA -SGRLDFGERYTVXPNDMRRGSGLIQTFEPGLPTLRSLVTQMIITSDNTATDMVIKAV-GL -DRVXALLQNEGFSQTRXKATTGDLFRAFEGDSTGKTTAREMGNLLEQILNAELADEEASA -EMIAMLTRQFY-TSRLPQRVRQGVSVAHKTGDWPPIAGNDVGILFYDGG-PSIVSVFTNQ -NTGDFFELEATLGLIAEDIVEAw ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis eurytherma TaxID=196083 RepID=A0A3N2H2E7_9PSEU -------------EAAGVRGWLHARCLDCGGET-GHHPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVTAADRLGGTGTAGCADDVEMSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLADTRVIGSPRDVVAALDPLRTSASTPRDMTTLLAAIAGDTAGPPEACH -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPGGERYAVAVFTKA -PTSRLPDVDHAIGEAAKAAIE-- ->[subseq from] Serine hydrolase n=1 Tax=Komagataeibacter pomaceti TaxID=2021998 RepID=A0A318Q7M3_9PROT ---TLSDDIAKTIQGQPGHFAVYAAMSGQPPQV-CLNCDDFIDAASTMKLFVMDAAYDSFT -KGTLHPQDMIVVHNRSLVGGSFALYAAIGRPVAVSELLRVMIQYSSNLATNLMIERI-GV -PYVRAIVAVQHLDGIRFGRMIEDYDAN-SQGIHNQVSARGLGLFLQKLDHGDIVGPAQSQ -AMIDIMKGQKF-NDMIPPGLPPGTPVAHKTGWVD-GVRNDAGIVFLPDGRHYILVMLTKS -LL-DEAAGIRVLNTISRQVHDSf ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura chibensis TaxID=392828 RepID=A0A5D0P0J9_9ACTN ------SEIAEVFGSAGARGFLHAREVGDGPEV-SVGAEDPVVLASVFKVPVAVAYACEVA -AGRLDENERITVTSGYRIGGIGTAGCADDVTMTWRDLVLFMMTLSDNAATDVVFRRI-GK -AAVDQVLRNLGLHRTRLIGCCADLFAVLDPARTTASTPREITTLLDAVWTDGAGPPAACE -RVRDIMARQVW-PHRLSSGFEPDVGVAAKTGTLP-AIRNEAGVVSYPDGRRYAVAVFTRA -DSDRLPRVDAAIGRAARLAVDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Niastella sp. CF465 TaxID=2135684 RepID=A0A4R2WDZ0_9BACT --nRLQQKIETQIKDLRGYIGVYVKNLRTGKVA-MVNADSIFPTASMVKVTILIGIQDKIE -KGQLEYHQQLEYKDSLLYAGEDILGSFKSGEIGLHKVLMLMLTTSDNTASLWLQSLAGAG -TRINEILDSLGLVNTRVNSRTPGREANRQQYGWAQTTPREMGTLMEKIYRGEVISKKASE -KMVRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPNG-PYIFSVQTKN -LQDNSNEAWVLTRKLSALCWNYf ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Candidatus Levybacteria bacterium GW2011_GWA2_40_8 TaxID=1618459 RepID=A0A0G0WLB8_9BACT ----LRKQVSDYTEKQKGSYSIYYKSLGKNSSF-GISENQIETGASVNKLPIVAALYRLDK -EGKLKLDEKITIQEKDVQDTGSIRYQKMPQVYSMRNLAKLSLRESDNTAAHVLSVRI-GV -DKIQELVDSWGMSQTNMGN--------------NKTTVYDMELLFEKIYKEEVATSANTK -ELLEFLTEGET-EDRLPKNLPKGTKVYHKTGDEE-GFVHDVGIIEVKKGA-YYLGVMTSD -IGDGEDATKKAIAEISKMIYE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID7804 TaxID=2690327 RepID=UPI0013714F2E ----------------------------DGREV-AVDADTPVVIASIFKVLLALEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVQLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPRDITRLLRLVWTDRAGPPQACA -LVRDLMHRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAIAVFART -RDASRPTVDAAIGRAAGMA---- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A350BNK8_9BACT ---DLQLQLEDAARSVRGTVGIYVRNLETGETA-AVNADTLFPTASMIKVPILCGVFDKIV -SGDLEYDSAYVYRDSLLYAGVDILGSFRDSAITLSKLVMLMIATSDNTASLWLQSMCGTG -TAINDWLERNGFHATRVNSRTPGREELRKHYGWGMTTPREMAELLAYIRVGKAVRPDAGE -EMYRVLSNIYWSD-GALSQIPPTINAASKQGAVDE-SRSEVVLVNAPHGD-FVFCVITKD -LQKRENEASTLIRKVSSMLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Root431 TaxID=1736535 RepID=A0A0T1Q5S0_9ACTN -haATRRRITAAFADAGVTGQLHAADIDTGTAL-GVGSDTLVPTASVHKLCLVATLYRQAS -LGLVDPTRPVDIPAEGRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNATMIGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE -ELRALLGRQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAAIGAAARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A149U7R0_9PROT ----LAQSISKTVKAQPGHFAVYAALSGHSSAV-CLNCDDLINAASTIKLFVLDAAYDAFT -NGTLHPQDTVTVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGRHYILVVLTSG -LP-DEQAGIKVLNTLSSQTYAYf ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Firmicutes bacterium ADurb.Bin419 TaxID=1852892 RepID=A0A1V5MHM3_9FIRM ---DLLSIINNIVKNKSDIIRISVYDFETDKSV-NYNDQEHFYAASLTKVVNLLCFLEEVK -NGKFDLNSTYTLKKSDKYVGAKVTYQANGTKYTYRDILSRMISLSDNVGANIIFDAL-GS -NKIDSFCQKYELKDTKIYKKFYDANSAVP---SNYTTAADLTRMLVLLENRVVADDSLAT -MGIEFMKNTDN-KDRIPRNAPKDVVIANKIGSLSR-LAGDMALIYFPDRDPIALTIVVEG -KNINEAEANELIGQLSKEIINYy ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. WB02_MRS01 TaxID=2605777 RepID=UPI0012B351D4 ---TLEKRIEAEIKSYDGKMGIYLDDF-HGNVI-AIHADEAFETASSIKTYILACLFDEVE -KGNKSLEDIIEYKVEHAVDGSGVLAAEPGAKLRVKDAATFMIIVSDNIATNMMIDYL-GL -EKINQCIKALGCRDTVLHNPIHF-E---QYDRLGTSTPRDYASIFIRLAKGELISPRADE -MMLEILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000D92CFB5 -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIQDNFDISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H3X4X2_SELRU ----------QVIGANNKQLAVYFLRPGREVEP-FIYNQRRMFPASMIKLFVMAKTMQDVH -DGRLSLEEQLTIRKQDVVGGAGVTTWYNAGERTIAQLIQLMVVESDNTATNMLIDKL-GM -ANINQYLQQYGYKDTLLVHKLMVNKKA---SNKNLSSVRDIGHLLTNLYYHQLVGEREDA -FMLDILKQQRD-KECFPAVVS-GYDIAHKTGEVN-GVYADGGIFYGPQED-FILVALSNS -NE--------------------- ->[subseq from] serine hydrolase n=1 Tax=Olivibacter sp. XZL3 TaxID=1735116 RepID=UPI0010657DD9 ---KLQKELALLTKDFEGTVGIYVYHLGKRKEA-SINADTLFPTASIVKVPILVGLFDKIE -KKELFYHQPLTYRDSLKYGGSGLMQFFKDSTTDLSVLAALMISYSDNTTSLWNQALAGGG -SAINKVMERYGLQFTRVNSRTAGRENDWKKYGWGQTTPREMAQLLVKIRQGEAVNRAASE -RMYRLMTNIYY-DEYALSQIPPYVQCASKQGMVND-SRSELVMVNAPHGD-YVFYVATKN -LKEEDNSAWQLARKISAHLWRYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB01635 TaxID=2020326 RepID=A0A2M9JH43_9ACTN ---AIADEIAAVFAEAGAQGFLHAREIGDGPEV-AVGADAPVVLASVFKIPVAVAYVREVA -AGRLDETERTRVTARYRVGGIGTAGCVDDVEMSWRDLALFMLTMSDNAATDVVFHRV-GQ -DAVDRVLTDLGLSRTRIRGCCEDHFAVLDPARTTSSTPREITRLLDAIWTDRAADPGACE -KVRAIMGRQIW-PHRISSGLDTGVQVAAKTGTLP-AIRNEAGVLTYPDGRQYAVAVFTRA -DSDRRPAVDTSIGRAARLAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus fabifermentans T30PCM01 TaxID=1400520 RepID=W6T7F2_9LACO ----VQKVVTTNLAGLSGKSSVAVLSVDSSAKV--VENNTKQRAASLIELFIMITAYQQVK -AGTLNLGDTYLLQASDKVGGTGNMQSLPNGTFSYQQVLNRMITDSDNTAANIMINKVGGI -AVVNAEIKRLGLTHTVLARKLMDTS-ALQAGKDNYTSAGDVAKVLKKMYNHQLIDATEDA -AMLDILAKNTD-HTMLPHSLPSEAQVYNLTGAYTYGVKNDAAIIKNNYGA-FVVVMLGEN -GQ--ASAQTKAMNQLGNSLY--- ->[subseq from] Beta-lactamase class A n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=A0A1I3M384_9FIRM -------------KSIEGDVSFYYKNLITNKTV-AYNEEKIMLAASVIKITVLVEAFKQIK -EGKIKKEELFTTCEDDKVPSCGALNYMREGLVTLEDLYILMIILSDNYATNMLIDKL-GM -DNINNTIKEIGLKNTVLNRKMFDSKKATLG-LENYISASDVGYLLEKMYNKDLIDKKSSE -EMISILKNQRLNGKMFLQNLKPKIEIAHKTGEDTN-ITHDVGIVFAK--EPFIVCFCGNN -V--NVPEYERLIQDITYDLY--- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma sp. KCTC 42546 TaxID=2520506 RepID=A0A514ZVA3_9BACT ----LERKLRAAMANFQGDAGIYVRNLRTGKTV-AINADTLFPTASMVKIPIQCGLFDKIY -KGELTYDQELIYKDSLHYDDGIIGSLKDGAKITLSKVVMLMETVSDNTGSLWCQALAGGG -TSINTWLETNGFHQTRVNSRTPGREANRTQYGWGQTSPREMAELLTYIRQGKAISPDASE -EMYRNLGRQHWDNDGL-SQVPPDVKIASKNGAVNQ-ARSEVVFVHAPHGE-YVYCVMTKN -QKDETNEGYTLLRAVAATLWHHf ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. NCIMB 12038 TaxID=933800 RepID=A0A1Y5LP69_9NOCA ---------------------------DDATDI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSELGLTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWAGRAVPGAQGE -FVRHVMSAQIW-QHRIRSGFPSGVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Segetibacter aerophilus TaxID=670293 RepID=A0A512BJI4_9BACT --kKLAVKLQELVGSFNGRAGIYVQNLKTGKTV-AINADTLFPTASMIKVSIQCGLMDKIE -KGELQYNQKLVYKDSLLYPGEDILGSFKDGDIQLSKVALLMITMSDNTASLWLQKLV-GG -EYINNWLQQNGFVNTRVNSRVAGREAMRKTFGWGVTTPREMCQLFTMIEEGKAVSKAASE -RMSRNLARIYW-DESALSQIPPHIRSTSKQGAVDD-SRSETVFVNAPHGN-YVFSIITKN -LKKPGNEAWTLIRKVSALLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A3N5XTA2_9BACT ---ALDARVRAEIAQFPGKVSLFAKNLDSGVNY-GFGADDLVRTASTIKVPVMIEAFAKVA -AGRVQWTDKVLLTDAKKISGSGVLQELSDGLLGLRDAVTLMIVLSDNTATNLVLDVL-TT -DAVNARMEGLGLTQTRILRKVGGGGVANARFGLGVATPREMVLLLEKLERGDVVSREAST -EMIKLLKRQQD-HEGIGRTLK-GVEMATKPGALDR-LRSDVGILYTRRG-RIAMAITCDE ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNH099 TaxID=1137269 RepID=UPI0004BBC9F4 ---TPRSRIRQAFADAGVTGRLHARDIDTGADL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLAAPVDIPAAGRTPGPTGLGAMCDAALSLRDLAVLAVSVSDNTAADVLWDTV-GI -DAVNRTMAGLGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQTW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Thermoanaerobacter sp. TaxID=1755 RepID=A0A3B8MZC9_THESB --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR -DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 61 TaxID=2035242 RepID=A0A2G7CVQ4_9ACTN ----TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQQAA -AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG -AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2132.2 TaxID=2485161 RepID=A0A3N1VG01_9ACTN ----TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQQAA -AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG -AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus koreensis TaxID=2054903 RepID=A0A2K3UZ37_9DEIO ------------ARGFRGEVGLCVSDLEGQELL-ALQPVRVFPAASTIKMPLLVLALELAQ -RGELELSARVEMRAADRVSGAGVLHELQGGLLTWQDVLTLMIIVSDNTATNMLIERL-GM -EAVNGWLSERGWAATRLIGRLEQRNEAQRRGERNRTTAREQVELLGALARGELLDGVHTG -LALDILGRQQY-RDIIGRRVPRAYRLCSKSGELS-GVHHDVGLLFTP--RPLIVALLSEG -GTDM------------------- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus TaxID=1386 RepID=V6T4J2_9BACI ---ELRDRLSNELAGCKGRASLFLEI--EGEII-EVNSQQVYQSASLIKLPILIEALRQIE -AGKLQKDRLVTIKESDKIGDTGVLQAMKVKQLPVEDLLSLMIIVSDNSATNLLIDLI-GI -NSVNSTISRIGMKNSILQRKMLDFA-AIQSGHDNFTSAADIALCLKEAVAGGALNTHSKN -TFFSFLLQQQF-KEKLPFYMDALLKIVNKTGELP-GVEHDCGIITYGKK-QAFIVVLIDG -LSET-ESGKTTIRQIGKHI---- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora orduensis TaxID=1420891 RepID=A0A5C4QFH5_9ACTN ----VGERIEAIFADAGVTASLHAVDLDAVDREaGVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLATELGLTRTRVLGGPRELVEVFDPEHTTSSTPREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DQPRRIDVDLAMGQAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI00130EC27F ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-SIGADETFETASAIKTYILACLFDEVE -KGNKSLEDMIQYREEHVVNGSGVLEALEPGALRVKDAAALMIIVSDNIATNMIIDYL-GL -DTINRCIKALGCKDTVLYNPLHF----EKYDRLGTSTPRDYASIFTRLAKGELISRPADG -KMLEIFKKQHY-NSMITKDFPAVITVASKSGSMD-ACRNDGGLVFTPYG-PYVIVMFHKE -FSDAAHPATVFGARISRMILDQf ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis australiensis TaxID=546364 RepID=A0A1K1S5J9_9PSEU ---SAEAAIDAVFTGAGARGFVHAREIGGTAEV-GVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETARTRVGKRYRTGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRV-GQ -AAVDRVLTGLGLRRTRLIGCCEDLFAVLDPARTTASTPREITTLLEAIWTDRAGDPAACE -RVRSMMARQIW-PHRMSSGFASDVAVAAKTGTLPS-VRNEAGVVTFPDGRRFAVAVFTRA -HSERQPAVDAAIGEAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW179A TaxID=2575510 RepID=UPI000E0EF954 ------ARWQTLAAEQDLKVSAFMLVLDDGRYA-QLEPDTALPAASSIKTPILLVTLEELD -AGRLSWNEPLKLSKTVVGGGAGWMATPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGQ -ETLNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSIT-NTLLPRGLLRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] Serine hydrolase n=3 Tax=Faecalibacterium TaxID=216851 RepID=A0A2J4JP78_9FIRM ---TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA -EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K404 TaxID=2530385 RepID=A0A4R4UFZ5_9PSEU ----AEQRIRDVLADAGAEGWVHAVRLGGGHEL-GFGADELVVTASVYKLPLLVALARAFD -AGTLDPREAIRLDPGSCTPPTGVSTFQDPVRMSWRDLAASMIAVSDNAAADVILGAV-GL -DALAATLADLGLQRTRVVGGTADAHAAYDPSYASATTPREMTGLMELIWADAVASPQQCA -FVRRLLGQQAW-MHRVRAGFPQGVRVSGKTGTIG-AVRNEVSVVEFDGEAPVAVAIFTLA -ARADLPRVDAAIAECARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter endophyticus TaxID=2675003 RepID=UPI000E0DB94B ---KLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS -EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTLIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETILVNAPHGD-YVFSIITNH -NKTPNNEAGLLIKKISALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MYSH2 TaxID=2303333 RepID=A0A372NYP1_9SPHI ---RLTAQLQSLIKNFHGQAGVYVHNLKTGKTA-AINADTLFPTASMIKVSILNGVMDKIE -KGELQYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG -DYINNWLAANGFKVMRVNSRVAGREAMRNIYGWGVTTPFEMCRLFTLIHDGKAVSPGASE -RMARTLNRIYW-DEKALSQIPPYVQTMSKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN -NQDQDNEAGILIKKVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Algoriphagus aquimarinus TaxID=237018 RepID=A0A5C7AX46_9BACT --kKLESSISVLTESFHGDVGIYIQNLQSGATV-EINADTIYPTASIVKIPILLGIFDKIE -KEELHYREPLIYRDSIRYGGSGIMQFFKDSTTDLSTLIALMLSYSDNTTSLWNQSLAGGG -AEINELMDRIGYQNTRVNSRTVGRESIWEKYGWGQTTPREIADIFIKLNNRELISTAASE -QMYRLLSNTFY-TDYALSGIPAGVNVASKQGMVN-ASRSEVFLVNSPQGD-YVCAIFTDN -NEDKDNEAWVMTRKISNLIWNHf ->[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. ND2010 TaxID=1410618 RepID=UPI0009079419 --eSLAQAVEALSNSDSTQYALFVAYPGENRAV-YSYHSTQMRSASMIKVFILGTAMEKIR -DGKLSLYQNLILHSYDKVGGAGVLAGYASGTFTLDTIMRLMITESDNTATNMMIDLL-GM -DEINAYIKRQGYKDTILQRKMMDSQA-VAAGRENYTSVNDLGDFFVKLYHRNCVSPELDD -VMLGYLEGQTD-TECFPAALP-GVMICHKTGELY-GLYDDGGIVYQPGR-HFIIVGMTEN -YS-SRGRAIAILRQMAIAAA--- ->[subseq from] Serine hydrolase n=1 Tax=Sulfobacillus sp. hq2 TaxID=2039167 RepID=A0A2S3QHG9_9FIRM ---NIHQAIAQWSQHFSGRFTLYAEHLQTHEVV-AHEPTRLMETASVIKLPIMIAAMDQVE -AGHLDLATPLVYTRDDYVEGSGVVQNLTPGFLSLHDALTLMITVSDNVATNMVLRQI-GL -ETVNAVMHRLGTPHIHLYKRIDFAQ----PGPIGIAPADEIGGLLKSLYHRTLISPWASG -IMWDILTRQQY-NTIMTRDLPYHVQIGSKSGSLE-GIRNDVGIVTSKWGD-YTVALFSAE -CEHVDNEAMRLLPRLTRLLFDHf ->[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A233RME1_9ACTN ------RTIRSLFDDAGVRGWLHVAELDRPSAHvVLDPDEQVPMGSVYKVPLMTTFCRLAE -AGRIDPSHRLTLETADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRAV-GP -EAVDRVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPADIARLLRAIWTDEAASPGSCS -FMRAAMGTQAW-AHRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=UPI0009A1177F ---QIHTALSSTFTQAKVEGTVHVRDLDTGAEF-AHAADTPVVLASVFKIPIALEYARQAA -SGELDPARRHSVTSAYRAGGSGTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIV-GP -DRVRATLDGLGLPGFGFSSCS-ALDDACTPGTSPSSTPREVTALLAAIWHDEAGPARACA -EVREIMRAQVW-QHRLVSGFPPGVRLAGKTGTDFS-VRNEAGVIEYPDGKRYAVGVFLRT -STTRQPLADRAIGRAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A1R1K0C0_ALCXX --qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRHALEQPLALPPGDRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNTLIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FT--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Ruminococcaceae bacterium D5 TaxID=1520815 RepID=A0A1I3PY27_9FIRM ------NEIYRILSEMKGTVGLYIEDCATGEIL-KINPELSFPACSVIKIPMLALLLRDGA -EGRIDLDAPHKIAAENRVGGTGILCDLNPSYITLRDLGKLMIIMSDNIATNEVMDVI-TV -DRFHAFCKEQGYENIIWQRKMMDFE-AIKQGRNNYLCAGEIGDMLSRISRGEFVSPEISR -TIFEFMCAQKY-RNKLPSLVPAVVLVANKTGDLV-GIQHDVGIFELPSHSRYIISMCTKD -LEND-LDGITTVGKVSLAVYE-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter tropicalis TaxID=104102 RepID=A0A252A3K3_9PROT ----LAQSISKTVKAQPGHFAVYAALSGHSPAV-CLNCDDLIKAASTIKLFVLDAAYDAFT -KGTLHPQDTVTVHNRSLVGTGTFAYAQAGKLVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD -LP-DEQAGIKVLNTLSHQTYTYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. MB95 TaxID=671602 RepID=UPI0013F5B2E6 -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMASDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. AF10-46 TaxID=2302955 RepID=A0A3A6JF79_9FIRM ---TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA -EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] serine hydrolase n=1 Tax=unclassified Faecalibacterium TaxID=2646395 RepID=UPI0012AF4AF6 ---TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA -EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A4P5U0C3_9BACT ----LQKQLEKEVAGFKGDVGIYVYELKKDKVV-DIHADTVFPTASIVKIPILLGVMDKIK -KGELAYHQKLIYKDSLLYEGEDILGSFKNGEIELSKVMMLMLTTSDNTASLWLQSLAGTG -LSINALMAQLGFIHTRVNSRTPGRENNRDKYGWGQSTPKELVQLFQQMLKGKLLGKSSDD -LMIKRLGRNYW-DEEALAEIPAGIFTASKNGAVN-ASRSEVVYVNHPKN-PYIFCIMTAN -NSEADNEAWVLTRKISKLLWQYf ->[subseq from] Beta-lactamase class A n=1 Tax=Lapillicoccus jejuensis TaxID=402171 RepID=A0A542E416_9MICO ------QRLRDLVAAAPGEVALAVRR-HDGAAL-DVGADRVVPSASTIKVPVLVAVLRAVQ -DGRLALDEPVPLPPPERVGGSGPLELLPSLTLPVHELLLLMICLSDNDATNVLLDRVVGP -GAVAAALALVPTRATHLRRRLMDAQAA-ARGLQNETTAADLVDLLVALRERRLLDHERTG -VALDVLGRQQF-REGLPAYLPESVPVASKTGEIF-GVRADVALVEPQPGRWAVVAVVATG ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Ruminococcaceae bacterium TF06-43 TaxID=2292270 RepID=A0A417NH15_9FIRM ---ALKEKILSQLSQMEGQVGFYYKNLVTGETL-AYHENEQFMAASVVKLPLLAAIMLWRE -QGKTCFDEHITVHKEQMHPSSGVLAFMTGDELDIKTLCNFMIIISDTTATNALYHHY-GN -ELVIATLRELGLSGTQFNREYYDSERE-DQGIQNYFVPAEIGTLLEKIYNRTLVSVQASE -EMEKLLLCQQV-NHKMGGSLPVGYPIAHKTGEEED-KTHDVGIVFA--REPFVACFASCQ -SN--IPEFENFIRQTTRSLVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_13_45_10 TaxID=1798370 RepID=A0A1F5ZGB5_9BACT ---ELRRKVEETIKDTWKNYSVLVVDYHSNFTM-GINDAVIFNAASINKIPILAALYTDVQ -KGDVDFDKVIILQSQDVQDGTGIIRYDPEGTYTVKTLIRLMMQKSDNTAAHILGNYIIGL -DRVQTLVNAWGLTQTDMA--------------NNKTSNKDMAILMDKIFRGKIAGVALTQ -EILAFLKDSDF-EDRIPALLPKNVTVYHKVGTGT-GTVHDVGVVTQGKT-AYYIGIFSSD -IT-DEERASKLAAQVSKVVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535X3K2_9CHLR ---TLASRLDHALLGVDGQIGVAVKDLGSGRGA-VLNGDLELPAASLYKLPVLYAVFDA-- ---GLRMAEELPITDDALSYDAGTMELGAGEALSVAEALERMITISDNTSAVMLGGRV-GP -SRVNSSIAALGMNTTHYSLT------------RMTTSSLDILHLLDLLARGRAVSPAASA -DMLHLLLRQRV-NDRLPRLLPDAVRVAHKTGNLP-GTVNDVGIVYGPSA-TLAIAVLVSD -TT-DEAAAATGIARVAQAAFAYf ->[subseq from] serine hydrolase n=1 Tax=Actinomadura oligospora TaxID=111804 RepID=UPI0004BBB249 -----LRTIERAFAEAGVSGRLHAVDIDTGREL-GVGADDPVVLASVYKVPLLVAFLRLAA -RGVLDPSEQVTLRPDERTEGTGLSVMLDDVTMSLRDLACLMITVSDNAAADALYARV-GR -DEINAALEALGLRGVHVTGDGRDLFGSLDPSRTSDGTPRELTRLLSMIWRDEAAPAAECA -LMRRLLGLQVW-PHRLSSGFPDDVRVSGKTGTLLT-LRNEIGVVEYPDGGRYAVAVFTRA -SEAVAPRADAVIGTAARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Edaphobacter aggregans TaxID=570835 RepID=UPI00068973A7 ---ALEQRLEALAAQLKGHVALYATQLNTGKTV-AVDADRPVQTASVIKLTILFEAMEEVR -AGKAHWDEKLTLQKGDGVSGSGVLTFFDTPVLTLKDVLTMMVIVSDNTATNLAIDRF-GV -DAVNSRIAWLGLKDTHLYKKVMKPATDQPKFGLGKTTAREMATVMERIGRCELAGPGEAG -QVALTMLRNQFYRNTIPRYLETGSGIASKTGSLN-AVRNDVAIVAGKSG-PMVISIFTYD -NDTADNQAEMMVARLAKEIVEAw ->[subseq from] Beta-lactamase class A n=1 Tax=Sediminibacterium ginsengisoli TaxID=413434 RepID=A0A1T4M5R5_9BACT --kRLQAQVTALLNGFNGDVGVYVHDLQKNRVI-AVNADSVFPTASMVKMQILTGIMDKIN -RNELDYHQKIVYKDSLLYAGEDILGSFKNNEIELGKVIMLMLTTSDNTASLWLQSLAGTG -TRINELMDSLGLKVTRVNSRTAGREPNRLQYGWGQTSPREMVALMEMIVNNKVISDSVSQ -KMLRLLGRNFW-DEHAISQIPSDVFVASKNGAVD-ASRSEVLFVNGKKT-RYIFCICTKN -NKDKSNEAWVLTEKLSKLLWEYy ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=A0A561BRC8_9ACTN ------SRLRALFEDAGTRGWLHAIRLGSEGEV-AVDADALVPMASVYKLPLLVAFCELVD -RGALDPREQVTLEPSDRTAGPTGLSVLLDPVMSRRDLALSMMTVSDNAAADALLDVV-GL -DRLADFLSRHGLTGTRIRRGTAGNLRIYEAANASATTARDMTRLLGLIWSGEVLSAEQTA -FVRRALGLQVF-AQRLGSGFPDAVRVFGKTGTFA-ALRHEVGVVELPDGSAYAVAVFTRA -ARRKLPRVDQAIGTAARLAVD-- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) TaxID=266264 RepID=Q1LEX5_CUPMC ---RVETALAPLLAGTQARVAISLR-LADGKVVlEREAERVQPSASIIKLPILFTLLEQVA -QGHLQLEQRFSLDGLERVGGTGILSQLPSVQLTLAELVRLMIVLSDNLATNALIELL-GF -EGVNDWCDRAGLGQTRLQRRMMDAAAR-AAGLDNFTSASDAAAPLCWLLRDGSLPAPLRD -FALGLLADQRE-RAHFGAALPAGAMLANKTGQLP-GLRHDAGILTVGAY-SVVLAVLADG -FTDAGGDGAQWLAEAARIVA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter lappiensis TaxID=354630 RepID=A0A1N7E4L6_9SPHI --rKLTQQLNDAVKGFHGQVGIYVQNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE -KGEMQYNQKLVYRDSLLYKGEDILGSFKDKDVQLSKVALLMITMSDNTASTWLQKLV-GG -DYINNWLQQNGFKVMRVNSRVPGREAIRSIYGWGVSTPFEMCRLFTMIRQGKAVSPAASE -RMSRNMARIYW-DEKALSQIPTYVQTISKQGAVD-AAKSETVLVNAPHGD-YVFSIMTNH -NADQDNEASVLIKKISALLWHYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. DvalAA-19 TaxID=1839761 RepID=A0A1C4KUP3_9ACTN -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDRMCADLGLPHTRIHGGVVGTYDVYAPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7S030_9BACT ---ALHRTLDSLVHRFHGVLGYSINNLDTGERL-AVRGDETFPTASLIKVAILVTVYDLAE -KGMLSLDDPLTLLKIDQVPGSGVLQFHPQMTLSVRDAAVLMSILSDNTATNLLLDKV-VI -RRVWQKMEALGLPHTKVHSKVFLRIASSVKYGLGVTTPNEMARLFELMANGKAVTPKADS -AMLDILANNQD-MELMQRT-VAGLAVPHKTGATDS-VRTECALFRLQTR--VVACALTKQ -NADTDNEAQLALGKIGEAILRTw ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=UPI00126A688D ---------AAVFAEADARGFLHAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA -AGRLDETARARVGSRYRIGGVGTAGCADDVEMSWRDLALFMLTMSDNAATDVIYHRI-GQ -AAVDRLLAGLGLGRTRLAGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGEAAACE -QVRSMMARQIW-PHRLSSGFPAEVAVAAKTGTLP-AVRNEAGVVTYPDGRRFAVAVFTRA -NSERQPAIDAAIGKAGRLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5385 TaxID=1864822 RepID=A0A261Q6P7_9BACT --tRLQKQLKTLVKDFHGDLGIYVEDLKTHSVA-AIRADTIFPTASIVKVPILLGIMDKIQ -RGQLDYHQSVTLTDSLRYKEADLVNAKTGEKIEISRLLLLMLSTSDNTASLWLQGLAGGG -LRINQVLDSLGYQVTRVNSRTPGREAIRNRYGWGQTSPREMARLFTAISERKLINPSISE -KMLRLLGRQYW-DQYALSQIPPDVFVADKHGCVNQ-SRSEVFYVAGP--HPYVCAIFTKN -NREATNEAWTLTRKISALLWKYy ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535EEQ7_9CHLR -------RLASLFAGAGVDGYLHAVDLDTGREM-RHRAGEPVVLASVVKLGVLVELFRRFD -AGEMAPEGRVRVTPAERSAGPTGLSVMKDDVLSWRDLAQLMIAVSDNAATDVITLRL-GK -DPINATLRELGLGRTVLRGTCREIYDQLSPEHGNASTAEETTRLLGLIWRDEAASPDACA -AMRRILYTQVW-PHRLSSGFGDGVRIGAKTGTLFT-WRNEAGVVELPDGGRVAVAVFTRD -HDRHNPAADAVIGSAARLAVDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacter thermohydrosulfuricus TaxID=1516 RepID=A0A1I1XXX6_THETY --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Thermoanaerobacter thermohydrosulfuricus TaxID=1516 RepID=M8CV84_THETY --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SB3404 TaxID=2711219 RepID=UPI0013ED0983 ----VQRALREMFADAGVRGWLHVAELHRPEACvTLDPAEPVPVGSVYKVPVMAAFCRLVD -AGALDPRRPVTLGPADRMPPTGISILRDPVTVSLRDLVALMMSVSDNTAADAVLQRVGGP --AVDAVCRDTGMRDTHIFGGVATTLAVYDPVSKASASPADMARLLRAIWTGTVASPDSCA -FMREVMGRQPW-RHRLAAGFPDDVKVSGKTGTFG-AMRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGASARLAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=A0A427SYK2_9PSEU ----------------GARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVGKRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVLYHRV-GQ -AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAAEPAACE -RVRAIMARQIW-PHRISSGFGSDVKIAAKTGTLP-AVRNEAGVLSFPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. Aph1 TaxID=1202456 RepID=UPI00039F53B8 ----------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLALMIMASDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Serine hydrolase n=1 Tax=Dyadobacter flavalbus TaxID=2579942 RepID=A0A5M8Q6C4_9BACT --kKLTAMLEKALAGFHGNAGVYVRNLKTNQTA-AIHADSIFPTASMIKVPIMCGLFNKIS -KGEIKFDQELVYRDSLKYDNGIVGSFRDSTRIPLPKVVHLMISLSDNTGSLWLQAMAGGG -ATINQWLDANGFANIRVNSRTPGRKDGQAKYGWGQTTPKEMAELVAMIRNGKAINAAASE -RMYRYLGMQFW-DGEALSQIPPHIKTAAKSGAVNQ-ARSEVLVVHAPHGD-YVFCVSTKN -QQQQNNEGYTLIRKVSEIIWNHf ->[subseq from] Uncharacterized protein n=2 Tax=Streptomyces niveus TaxID=193462 RepID=V6KL92_STRNV ---------------LDARVWLHARCVDCGRGT-GHGQDEPVVLASVVKVLLALEFWRQAA -AGQLDPAERVVVRAADRLGGTGTAGFHDDARLSLRDLALLMMSVSDNTAADILFRRV-GL -DTVQALARQLGLDRAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGPAVACA -GVRDLMARQVN-GARLGAAFDRFTTVVAKSGTLP-GVRNEIGVVTCPDGARYAVAVFTRA -TSTRRPDLDAAIGEAGRGAV--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter cerevisiae TaxID=178900 RepID=A0A149UT15_9PROT ------QIMTKTVMKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYEAFT -KGTLRPEDTMTVRNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVKAQGLNGIVFGRMIEDFDAN-DQGIRNRVSARGLGNFLQKLDSGQIVGKAQSQ -NMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSD -LP-DEQAGIKVLNTLSHQAYTYf ->[subseq from] Uncharacterized protein n=1 Tax=bacterium BMS3Abin01 TaxID=2005709 RepID=A0A2H6K349_9BACT ----LMKRMSRILAGAGGDYGVYICELDTGDSF-GFNQHRPFEAASTVKIPIMMMLYGELE -AGNIGRDEVMTYLWSDYEGGTGSIQQGPGTTWTIGELATRMMKESDNVAKNMLLRRL-GY -GAVERYAHDQGAGSFDLY--------------NNRITPADMGLLLKRLYSGRVAGPQLTG -EMLSLMTGTTD-EDRLPRYLSGNISVAHKIGTMDD-TIIDVGIVRGA-GAPFIICVYSDM -VG-SEAEAEDIIGRLAWQA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinorugispora endophytica TaxID=1605990 RepID=A0A4R6V1M3_9ACTN ----TEERIIDLFDGADVDARLHAVDIETGREV-AARADEQVVIASMFKILLVLEFSRQAE -AGQVDPAERVTVGRADRLGGWGTAGCADDAELSLRDLAFFAMSVSDNTAADLLMRRI-GL -DTVQLLAAELGLERTRIVGGPRQVLEVLDPAHTTSSTPREMTRLLEMVWRDEAGPPRACA -AVRGLMGQQIF-WTRIASGFDAGVRIAAKTGTLPS-LHMECGVVEYPDGGRYAVSVFART -RRLERIDVDLAMGRAARAAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID9727 TaxID=2706114 RepID=A0A6B3BEP4_9ACTN ------TDLRAAFTDAGVTGWMHAVDIDSGAEV-DYEGHHVLSTASVHKLPLLVALHERAA -AGDIDLTELVDCPPDDRASGPTGLAAMADIALSLRDLAYLMMSISDNAAADVILQRV-GL -DAVNRTTARLGLTRTRALHSFGEMMAALDPAQSNRSTPRDLTRLLATIWRDTACTPEHCS -SIRRLMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEAGVVEYPDGGRYAVAVFTRT -VSAILPAADAVIGAAGRIAID-- ->[subseq from] Serine hydrolase n=1 Tax=Pradoshia eiseniae TaxID=2064768 RepID=A0A2S7MVH2_9BACI ---------DELLSVQEGNVSCVYLNLKSGETY-EYQKDMVHPSASVIKIFLMAYIYQLIE -EGAIKEEDRIAIKPETLAESSGVLYYLKDVHLSVRDLKELMIIVSDNTATNVLLGLA-GM -ESLQLYISELGYQHTLFQRRMMDFDA-VKRGFQNYTTAEETADFLKKLYLGKVVSPEASG -KMMQILREQQF-SNLVPYHLYPEQSIANKSGGLDH-VVHDAGIVLAGDA-PFVLCMFGSE -VD--VPSYSRVIQDVS------- ->[subseq from] Beta-lactamase class A n=2 Tax=Bogoriella caseilytica TaxID=56055 RepID=A0A3N2BGD5_9MICO ----LAATAAPLEAELGLTAFVHARDLDSDAQV-GLRSEDLVVTASVFKIPVLLEVCRQVA -AGERAATDRIDLGAEDFQVGTGIAAFSDPISLSLRDLYLSMMNVSDNRATDVVMDLV-GW -DRIAATLAELGMTQTVLEGDTAALFAAQDPRHSHRSTPEETTRLLGRIWNADGIDASACA -EVRRVMGMQVY-GHRLRTGFPGSVSVAGKTGTLSF-IRNEAGVVTFPDGRRYAVAVFLRH -RTADAPDLDRAIGTLGAAAV--- ->[subseq from] Serine hydrolase n=1 Tax=Siphonobacter sp. BAB-5405 TaxID=1864825 RepID=A0A2N7B5E4_9BACT --tRLQKQLETLVKDFHGDLGIYVEDLKTHSVA-AIRADTIFPTASIVKVPILLGIMDKIQ -RGQLDYHQSVTLTDSLRYKEADLVNAKTGEKIEISRLLLLMLSTSDNTASLWLQGLAGGG -LRINQVLDSLGYQVTRVNSRTPGREAIRNRYGWGQTSPREMARLFTAISERKLINPSISE -KMLRLLGRQYW-DQYALSQIPPDVFVADKHGCVNQ-SRSEVFYVAGP--HPYVCAIFTKN -NREATNEAWTLTRKISALLWKYy ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2575 TaxID=2512212 RepID=A0A4R7TCJ4_9ACTN ------GRIRAIFEDAGVRGWLHATPLDRPDESiEVDSDAVVPLASVYKLPLLVGFCQLVD -QGRLDPREQVTLLPEARTPGPTGLSLLADPIISRRDLAVLMMTVSDNAAADALLDHV-GL -DRLATILRELGLTRTRIRRGAADNLRVYEAANASSGTARELTRLLSRLWTGDLLSAGQTQ -FARTTMERQIF-QHRIAAGFPDGVRVAGKTGTFG-ALRHEAAVVTLPGGDAYAVAVLTLA -ARSDLPRVDAAIGEAARVAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter gossypii TaxID=551996 RepID=A0A1G8FUC3_9SPHI --sKLTAKLNEAVKDFQGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -EYINNWLNQNDFKVMRVNSRVPGREAIRKIYGWGVSTPREMCRLFAMIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYIHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NKTPDNEAGLLIKKVSALLWHYf ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter thermohydrosulfuricus TaxID=1516 RepID=UPI0009438495 --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter TaxID=1754 RepID=UPI00052668E7 --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ287 TaxID=2572908 RepID=A0A559VQB8_9ACTN -hrTARSRIRRVFAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTAAVDIPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAGRLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=A0A433L0J2_CLOPF -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-GM -DKINKTIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSECSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] serine hydrolase n=1 Tax=Acetobacter cerevisiae TaxID=178900 RepID=UPI0009EE77C2 ------QIMTKTVMKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYEAFT -KGTLRPEDTMTVRNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVKAQGLNGIVFGRMIEDFDAN-DQGIRNRVSARGLGNFLQKLDSGQIVGKAQSQ -NMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSD -LP-DEQAGIKVLNTLSHQAYTYf ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0008A2FD41 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAGDRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] serine hydrolase n=1 Tax=Hamadaea tsunoensis TaxID=53368 RepID=UPI00048A333C ----IEHRIAALFADAGAIGRLHAVDIDTGRQV-AVAADEPVAIGSVFKLPLVVALHRLAD -AGVLDLTEAVTLATGRTSGPTGIGAMRDPVTMSLRDLAHLAVSVSDNAAADAIADRI-GL -PAVAETLARLGLAGTAVTQLCRDIAETLDPGRTNRSTARDCTTLLTAVWRDTAAAPSSCS -AVRRLLSLQVW-PHRLAAGFPDDVRVYGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -ASLALPRVDAVIGTAARTAVQY- ->[subseq from] Beta-lactamase class A n=2 Tax=Kibdelosporangium aridum TaxID=2030 RepID=A0A1W2EYN4_KIBAR -----------------------------SREV-DVDADEPVVMASVYKLPLLVALCRQFD -AGRIDPRRTVRINPASCSPPTGIATFLDPITMSWRDLAVSMMTVSDNAAADLILGEV-GL -DTVGSTLADLELTGTKIVGGAADVEAAYDPAYTSATTPRDMTRLLSLIWSDSVASAEQCA -FIRRLMGMQVW-QHRIRAGFPGDVRVSGKTGTIG-AVRNEVAVVEYAHETPIAVAVFTFA -ARSDLPAVDAAIGEAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A2S8IQM8_RHOOP -------------------------------DI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLAMSMMTVSDNAAADLVLGQV-GL -ASVERTLSELGMTNTRIIGGTADSHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Serine hydrolase n=1 Tax=Echinicola sp. LN3S3 TaxID=2591634 RepID=A0A514CK23_9BACT --kKLSKALYSLMEDFKGTAGVYVEHLPSGKFA-AINADTIFPTASIVKVPILIGVFDKID -RGELEYHQPLVYRDSIRYGGSGLMQFFEDSTTDLSTLLALMITYSDNTTSLWNQALAGGG -ETINPIMEKYGMEFTRVNSRTPGRKGDWEKYGWGQTTPREMATLLKKIRKGEMISKVASE -RMYRLMTNVYY-DDYALSQIPPYVQTAAKQGMVN-ASRSELVMVNAPHGD-YVFYIATKN -NQKPDNESWVLARKVSAFLWEYf ->[subseq from] serine hydrolase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=UPI000472C323 ----LAQRVAETVADQPGHYAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYAAFA -KGTLHPDDTLTVHNRSLVGKGHFAYAQAGKAVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPVRSVVNAQGLNGIIFGRMIEDFDAD-AQGIRNRVSARGLGNFLQKLNNGQIVGKTQSQ -SMIGIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVRNDAAIVTLPDGRQYILVVLTSG -LP-DEQAGIKVLNTLSHQAYLYf ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb45 TaxID=1827294 RepID=A0A2S9BQB6_9MICO -------------------------GAEGGPEV-SVDADEPVVLASVFKILVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFSDDVEASWRDLAQNMMTMSDNAATDVVYHRL-GS -DAVNRVISDLGLRHTRLVGCCEDLFAAVHPAKTSHSTPRDVTTLLNALWTDTAATAEACR -QARDIMAQQIW-PHRLSSGFPPGVRIAAKTGTLPT-WRNEAGVVTYPDGRQHAVAVFTRA -ASLA-DRQ--------------- ->[subseq from] Uncharacterized protein n=1 Tax=bacterium TaxID=1869227 RepID=A0A2E4FZ88_9BACT -------QVATIIQPVSSNISLVVTHLGTNYTY-SWRPNQRYNPASLIKLPILACLYNRVA -SERASLSNTLMHRARHTQSGAGILKHARPGEYRLDTLANMMMRYSDNTATLMLIEYL-DR -QQINDYMRRIGMQNTWLKN--PHLTQP---PQSNQTTAMDIHQLLVQLARYELLSPTHTY -ELLSQMRQQIY-RWGIPHWLPPSFSVANKTGTLGS-VRHDVGLVIHNKD-AYVVSILTEG -LPK--GTRAATIARIAEAIL--- ->[subseq from] Serine hydrolase n=1 Tax=Sporosarcina sp. BI001-red TaxID=2282866 RepID=A0A3D8Z212_9BACL ---QLKQELQRISSDASGAVSLYASTPD-G-PI-AICPDEVQRSASILKVPIAMACLAAAD -RGEIDLDAQLKIEE--PVGGSGVLAYMTDMDMTLRNALTLSIIVSDNTAANLVIEYV-GL -ERIQAFFRQVGAEHSLVSRKFMDYD-ALAKGLENVATARDMVRFLACLDPSEFLSLTSKQ -QLKTIMRDQQL-IDKLPAYQPETLIIGNKTGTLP-GVEHDIAYFEKGNR-RVDIAVLTSN -WDYN-HDGQKTIAQIGKAIIEY- ->[subseq from] Serine hydrolase n=2 Tax=Actinobacteria TaxID=1760 RepID=A0A329R3H1_9ACTN --------------------------TAGLAEV-NVDADARVVLASVFKIPFAVAYAREAA -AGGLDPAERTTVTARDRTGGVGTAGCADDVEMSWRDLAMFMMTMSDNAATDVLYRRL-GY -RRIQAVLDDVGLHSTNIIGCCEDLFAVLDPARTSASTPRDLTTLLAAIWTDEAGPPEACD -EVRSIMAHQIW-PHRLTSGFPGDVQVAGKTGTLP-AVRNEAGVVTYPDDQSYAVAVFTRA -ESLDQPRIDAAIGQAARLAVEH- ->[subseq from] serine hydrolase n=1 Tax=Jiangella gansuensis TaxID=281473 RepID=UPI0004ADD4A3 ---RLRAGLASLAEAGPGRWAFAVWE--QGRPVvSLSGAEPVPAASTIKVPLLVLALQDVA -TGRRDLDDDVPVPA-ERAGGAGVLRLLPSVRLRFAELLTLMIAVSDNAASNLVIELL-GL -DDADRRLAALGLTGTRLRRRLMDTEAA-RAGLENVTTADDQSRLLDRLAGPDLLPAPLRA -FALDALAEQQV-NDRMPTQLGDDVRCLHKTGELP-GVRHDVGLLEFDGRT-VALAALGTE -LTDPA------------------ ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. OF03-6AC TaxID=2292356 RepID=A0A396LJT6_9FIRM ---TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA -EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Deminuibacter soli TaxID=2291815 RepID=A0A3E1NR37_9BACT --kKLEKLLGEALQGFNGESGIYVHDLNHNRVA-AIRADSLSPTASMVKMTILTGIMDKIH -RGELDYHQQLVYKDSLLYAGSDILGSFKSDEIELSKVIMLMLTTSDNTASLWLQSLAGGG -TRINAILDSIGFTATRVNSRTPGREANRQQYGWAQTSPREMAGLMEKIVQHQLVSDSLSE -RMLRLLGRNYW-DEEAISVIPSDVFVASKNGAVD-ASRSEVLFVNGRGR-RYIFCICTHN -NKDTGNEAWVLTRKISKLVWDYy ->[subseq from] Beta-lactamase class A n=2 Tax=Jonquetella anthropi TaxID=428712 RepID=H0UJN2_9BACT ---RVASQIANRVYESGVQASVVLADPATGEQF-DLRGLQRLKSASLIKLPILWDLFARAE -EGSLNLSETIVVPSEKRVDGGLLHKFSASPTLRLEDLAVLAGTVSDNTAANLLMDRL-GL -DGINDRIRSLGMKSTSLERRMLDSGAA-KAGKDNWTTACDVALFLSALTSTAGLSEAGKR -RIIDILSAQKL-QSKLAGAIPCDKVLAHKTGELP-GHEHDAGIFFPFGPRPAVLVVLTTG -LT-DRLDGVRFCSALGRLVYDEw ->[subseq from] Beta-lactamase class A n=1 Tax=Asanoa hainanensis TaxID=560556 RepID=A0A239GCY8_9ACTN -------RIAGIFAAVGVDAQLHAVDIDRGTQL-SVRADERVVLASIFKVLLVLEFARQAA -AGQLDPTERVLVRAADRLGGWGTAGCADDAELSLRDLAYFAMSFTDNTAADLLLRRV-GP -DVLPLLAAELGLTSTRITGGPRELLEVFDPDQTTSSTPREVTRLLELIWRDEAGPPAATA -MVRGLMARQIF-FTRIASGFPNGVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALAIFARA -HQLDFRRVDLAMGEAARTAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Faecalibacterium cf. prausnitzii KLE1255 TaxID=748224 RepID=E2ZF83_9FIRM ---TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQAQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFTRIAKGELVSREASA -EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. 14C53 TaxID=2508997 RepID=A0A5C4J3S1_9ACTN ----VAERVEAEFRDAGVTGFLHAVDMDTGREV-AVRADAPVVLASVFKVPLLVTFHRQAA -EELIDPSEQVTLPAAGRTTPTGVSGMLDEARMSLRDLTFMMITVSDNAAADVVLERV-GR -DAVNATSAALGLRDTVVEVSGRELHEALDPARTSRSTPRDMTRLLSMIWRDEAAPPPGCA -AMRRLFGLQVW-PHRLSSGFPDAVVVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -PLAVLPRADAAIGTAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum septentrionale TaxID=2290913 RepID=A0A398DRV2_9BACT --qDWQEQVRALLGGAQGKFGVYAAT-LTVPLF-EYQTSSVFPSASTIKVLIMAELLRQVE -AGTHALTEHP-VLPTAPTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIRLT-GM -DAVNQLAVDIGMTNTRLRRFMMDTESV-QQDIDNTTSPADMGRFFKLLACNELVSSRASA -TMKTILGHQQF-ADIMMLFLPEGIRAEHKTGGLP-GSVLDVGLVYGA-RDPLILCLMATQ -LAN-NGEGAVILGKVAAITYT-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. F01003 TaxID=2305909 RepID=A0A444MIK8_9SPHI --kKLTAQLQTALQGFNGQAGIYVQNLKTGKTV-AINQDTLFPTASMIKVSILSGLMDKIE -KGELKYNQKLAYRDSLLYAGEDILGSFKDKDIMLSKVAMLMITMSDNTASLWLQKLVTG- -THINNWLDSNGFKNMRVNSRTPGREAMRKIYGWGVTTPYEMCKLFTMIRNGQVVSPAASE -RMSRTLNRIYW-DNTALSQIPPYVQCLSKQGAVDE-SRSETVLVSAPHGD-YVFSIITKN -NKVTDNEAYVLIRKVSALVWHYy ->[subseq from] Beta-lactamase class A n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=A0A1G7VA29_9PSEU ---------------AQGFVHVREVGVENGPEV-GLGADDPVVLASVFKIPVAVAYAEEVA -AGRLDETGRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDAVFHRV-GQ -AAVDAVLARTGLVRTRIMGCCEDLFAILDPERTTSSTPREITTLLDAVWTGRAASPRACE -TVRSIMSRQVW-PHRLASGFGSDVQVAGKTGTLPT-LRNEAGVLTYPDGRGYAVAVFTRA -SSPDQPAVDAVIGRAARLAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar1 TaxID=2004467 RepID=A0A1Y0GW34_9BACT ----LKKQMDEVAAGFRGRLGYHVIDLKTGQRF-GFRDGERYPSASTIKTVVMIELFNQIE -EGKMSFEDKLEVPPVGQRNPSMWTAHLIEGTVNLDGLNSLMMNVSDNTATVMLSQHV-GI -QNIEKRMLGWGFENTACTIRTAGKGERLERLYQGVTSPVEMASILKMIHDGKAASPAACE -KMIRIMSSQYW-DDFIDWSVPSDVVIASKVGALQR-SRSDSAIVYGP--RPYILTIYTDN -AT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobacteria bacterium TMED177 TaxID=1986677 RepID=A0A1Z9JE80_9CYAN ------------ATQKDLQASAYMLVLDDGRFA-QMNGDRPMPAASSIKTPILLAALERID -EGDLHWNEPLVLTKELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLLIERVGGK -EEINTKFQELGLTATVVNNWLPDLDGT------XTTSARDLSRSIAIVDTGETLSPRSRD -LFREVMSTSVT-NTLLPTGLMQGYAVLNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTNLIRAMAKAMA--- ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter TaxID=434 RepID=A0A252EGX0_9PROT ----LAQSISKTVKAQPGHFAVYAALSGHCPAV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPQDTVTVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD -LP-DEQAGIKVLNTLSQQTYTYf ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI000BF2E528 -------------------NGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGILRALPRLTIKVEELLTLRIIVSDNTATNEFISLV-GF -EKINECAKNLGLKKTVLNRYMMDEI-AVEKGIDNYTCASDVVKCLREIYEGNLLQKSSRE -KIMRMLEMQQF-QHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVILIDG -LS-DNEQGRRLIADIGYL----- ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces niveus NCIMB 11891 TaxID=1352941 RepID=V6JHZ6_STRNV -----RDRIRAAFAAAGVTGWLHAVDIDSAAQI-EVGADQPVVTASVHKLCLLVALHQHAE -AGRLALTDQVESPADGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAAELLLARV-GL -DAVNETTERLGLRRTHAVQTFGEFITALDPARTNRSTPRDMTRLLGAIWRDEACTPEHSA -AVRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA -ASAALPAADAVIGTTARIAID-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 278922_107 TaxID=1292019 RepID=UPI00048D8EFE -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIGAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGSDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. QHH-9511 TaxID=2684468 RepID=UPI0013193665 ----VRTRITAAFTDAGITGQLHAVDIDTGASH-GIDADTLVPTASVHKLCLIATLYRQAA -LGRLDLRQPLDIPAEGRSPGAGLAAMRDAARLSLRDLATLAVAVSDNTAADLLFDTL-GL -DTVNQCMADLGLTRTVARHTMRELYAALDPARTNHSTPREITGLLTAAWRDDICPQEYAE -ELRTVLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -AAVTLPAADAAIGRAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RJJ4_9BACT --eDLQQKIEQRIKEFGAEVGIYYEK-PDGSIF-THNADAIYHAASTMKVPVMMEVFREVE -TGELSLDQKMKIMNESIVDGSKFSYNWIGKEKPLRELLERMITRSSNLATDLIIGLV-TP -EKVRALMTKIGAKDMYVLRGVEDIK-AYQAGKINTTSAHSLAICMKELMDPKLFSESSRN -EMFEILTHQEF-RKGIPKGIHSDLIIANKTGDLTE-INHDAAIIRDSKGATSILVILTRG -VK-DDAKGKELIAVLAGDIWD-- ->[subseq from] Beta-lactamase class A-like protein n=4 Tax=Microgenomates group TaxID=1794810 RepID=A0A0G0QSE6_9BACT ---RVRREFKEKTKNLSGVYGLFVIHLDNGFSY-GVNENETFTAASLIKLPVMAEMYIEME -DGRLRMEDRYTLKNSDKVAGAGSLYGKPAGYITYRNLIQLMGKQSDNTAFNICRKLL-GD -EKIDEVIRSVGMVDTSLEK--------------NETTPKDIGIFFEELWKGNIVSEESRD -EILGALTDTIY-EDWLAAGIPEGIRLAHKYGREVH-VVNDAGIVFTD--RPYVVVIMSKG -VV--EREADEIFPELAKLVYE-- ->[subseq from] Beta lactamase n=2 Tax=Rhodococcus TaxID=1827 RepID=Q0SKC5_RHOJR -------------------------------DI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTASVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ASVERTLSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Lechevalieria fradiae TaxID=200378 RepID=UPI000B7C7482 ---------------AQGFVHVREVGVENGPEV-GLGADDPVVLASVFKIPVAVAYAEEVA -AGRLDETGRTRVTSRYRIGGIGTAGCADDVEMSWRDLALFMMTMSDNAATDAVFHRV-GQ -AAVDAVLARTGLVRTRIMGCCEDLFAILDPERTTSSTPREITTLLDAVWTGRAASPRACE -TVRSIMSRQVW-PHRLASGFGSDVQVAGKTGTLPT-LRNEAGVLTYPDGRGYAVAVFTRA -SSPDQPAVDAVIGRAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces spinoverrucosus TaxID=284043 RepID=A0A4Y3VL86_9ACTN -------RVRAAFAEAGVTGWLHAVDIDTGAQL-DAGADQPVCTASVHKLCLLVTLHELAD -TGDLDLTEQVDCPPLGRTPPTGLAAMRDPVRMSLRDLAYLMTAVSDNTAADLLLGRV-GL -DAVNRTTARLGLTRTHAVHTFGELLAALDPARTNRSTPRDMTRLLSAVWRDEACAPEHAA -AVRRLLGLQVW-PHRLASGFPDDVHVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADSVIGTTARLAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacter siderophilus SR4 TaxID=880478 RepID=I9ACE5_9THEO --qELKNNIQALISRYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Flammeovirgaceae bacterium TMED290 TaxID=1986700 RepID=A0A424PC02_9BACT ---------------------------DDGKSI-LINENEFFHAASTMKTPVMIEFFKKIN -EGKISSDDSLLINNESIVDGSKFEYENLGKYISTDKLVYDMITRSSNFGTNLLIDYL-NV -EDVNNTMKNIGAKNMKVLRGVGDLKA-FDLGLSNSTTAADLLIIYEKLAMGEIVNNESSN -KMIRILKDQVY-NDIIPKYLPENVEVAHKTGWIS-GVRHDSGIVYVGNNKKYILVLLSKN -LE-DDVEGADFLAKISLEIYN-- ->[subseq from] serine hydrolase n=1 Tax=Cupriavidus malaysiensis TaxID=367825 RepID=UPI0008A6AACD ---RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG -QDRLRLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALIALL-GF -DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGRDNFTSAGDTAAALGWLLRGDTLPAPLRA -FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG -FTDPRTARE-------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. 12(A) TaxID=1163671 RepID=UPI000466C3B6 ---TLEKRIEAEIKSYDGIMGIYLDDL-RGTVI-QIKADETFETASAIKTWILACLFWEAE -NGRACLEDQIEYKKEHWVDGSGVLGALEPGALRVRDAATFMMIVSDNIATNMMIDYL-GL -DRINQCIRRLGSMDTVLHNPIHFDQ----YERLGTSTPRDYASIFIRLVKGELISPEADR -QMVEILKKQQY-QSMITKDFPPYISVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE -FSYPAHPATMFGARVSRLILDQy ->[subseq from] serine hydrolase n=1 Tax=Nakamurella lactea TaxID=459515 RepID=UPI00048EBFCA ------------AARAGADVFAHALDIDSGAEV-GINSDHPVVTASVFKVPVLTEYVRQVS -SGELDPNARVTIRAGSATIGPTGLSVFSDDTWSLRDVATSMITVSDNGATDIVTGMV-GV -DRVNATMRSLGLPSTALIGDCAALFAVCTPERTNRSTPRESARLLQLLWTDQAAGPAACA -EARRILGLQIW-PHRLSSGFPDDVKISGKTGTIGI-VRNEIGVVEFPDGHRYAVAVFTRS -HAYRQPAVDALIGTVAAALVD-- ->[subseq from] serine hydrolase n=1 Tax=Senegalia massiliensis TaxID=1720316 RepID=UPI0013EF5810 --------LESIINEDKLKYSLYVEDLKTNKIIfDINSDAEVTSASMIKIFIMAEAYSQIS -KDEFMSQKIVNVDRDNIVGGSLIKN-LSNYCYSIKDLIFLMMNLSDNTATNQLIDIL-RI -ENINKFISEEGLKNTVINRKMMDFERK-KKGFDNITSSRDIAHILKKIYYKDLIDKDASV -NMMNIMKKQMDNRMMARNIDKSNTKIYHKTGNIPY-TNHDAGIVIFKDIE-YLF-VMLTW -DAYDNIYGRKVIGEVSEKIYNDf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNY243 TaxID=1169161 RepID=UPI00036C340B -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRIDLTTVVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNGTMAALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium Uphvl-Ar2 TaxID=2004468 RepID=A0A1Y0H8I5_9BACT ---TIEPQVRAVAERFRGRLGYHIQDLTTGEVI-AHRSTERFPSASTIKTVLMFEAARQID -KGELTWDTTVPLPPVAERNSSQWAYYLREGLINVDALTNLMMNVSDNTATVVLGEKL-GL -LRINQTLQEMGYQDTAYTVRVPETETRRQFANMGVTSPQEMARFLLMIDRGGVLSEAAHD -RMRRILAKQYW-DDWVMGTVPSDVVVLSKVGALNR-HRSEIAIVKGP--RPYLVAIYTDN -QADQENEGDQAIIRIGTLLWNH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Tu6071 TaxID=355249 RepID=UPI00031B1C5E ---AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARI-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIVVD-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter rubeus TaxID=2027860 RepID=A0A364WUS7_9SPHI --sKLTAKLNEAVKDFQGQVGIYVHNLKNGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -EYINNWLNQNDFKVMRVNSRVPGREAIRKIYGWGVSTPREMCRLFAMIREGKAVSPAASE -RMYRNMGRVYW-DEHALSQIPPYIHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NKTPDNEAGLLIKKVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A179TAF6_ALCXX --qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA -NGRYALEQPLALPASDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWLLRDDTLPAPLRA -FALDVLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=UPI000BE47DF1 ---TLEERIKAELASYNGTMGIYVNDF-QGNKV-EINIDEEFETASTVKTFILGTLFDEVE -KGNKNLSDKLIYTQENEIEGSGILRSLDYGVLTVKNVATLMIIVSDNIGTNMMIDYL-GI -DTINAFMQSYGFTHTKLHNKIN---FD-IYDKLGTTTPRDYGKIFEMICKEELISPEASR -QMLEIFKKQHY-NSMLTKSFPQYIYVASKSGSMD-ACRNDGGIVSTPYGK-YVIVLFNKN -FTDPEHQATVFGSKVSRLIFDQy ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter siderophilus TaxID=106578 RepID=UPI000586F9AA --qELKNNIQALISRYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMSMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYTIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. IB2014 016-6 TaxID=2517818 RepID=A0A5C8Q918_9ACTN ---------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQAV -AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GL -DTVQALARQLGLERVRVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA -GVRELMSGQVN-GARLGAAFDRFTTVAAKSGTLP-GVRNEIGVVTYPDGARYAVAVFTRT -ASTRRPDLDAAIGGAGREAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HVD8_9BACT ------------EEGDSIHIGIAVLDMETGRSL-EMNAERVFHAASTMKVPVLLEWYRQSE -LGIRSLDEGVRVHNRFRSVGSEVLDEDVDEGLPARRIAEGMIQVSSNLGTNILLELL-TA -DSVQATMARIGAPEMQVLRGVSDIPA-FEAGLSNRTTARAYLRVLEAIARCEVTSQASCD -EMMEILEGQEF-RSEIPAGIPAGTRVGNKTGSITR-ILHDGAIVQPTGRAPYLVVTLSEG -YE-DKDHGSRTLSDLSGIIWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces silaceus TaxID=545123 RepID=UPI0006EB9913 ------------FAAAGVTGRLHALDIDSGAEV-DAGADQPVVTASVHKLCLLVTLHEQAA -AGVLDLTEQAECPVEGRTPGPTGLAAMLDPVMSLRDIAFLMMSVSDNTAADLLLERV-GL -DAVNATTARLGLERTHATHAFRELLAALDPARTNRSTPRDMTRLLRAVWRDEACAPEHGT -AIRRVLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -AGAILPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-128772 TaxID=2073159 RepID=UPI000CD31B36 ----------------------HAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA -AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRV-GA -EAVDRVLTDLGLRRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTGRAGDPAACE -RVRSMMARQIW-PHRLSAGFPSDVAIAAKTGTLP-AVRNEAGVVSFPNGRRFAVAVFTRA -DSERQPAVDAAIGRAGRLAVDH- ->[subseq from] Beta-lactamase class A n=2 Tax=Acidipila rosea TaxID=768535 RepID=A0A4R1LDH7_9BACT ---ALEAQLQTMTAGYHGKVALFAKDLTTGQTV-ALNADTPVQTASVIKLTVLYDALQQVR -AGRVHFDDKITLTKQDQVQGSGVLMFFDTPLLTLKDVLTMMVIVSDNTATNLAIGHL-GL -KNIDDEIVALGLKNTWLYKKVFAPAESMPADQTGKTTPREMASVMQRYVDSTAAKTAEDE -QLCGHMLKNQFYRDSIPRYLEKDSAIANKTGALD-AVRNDVGVVYAKSG-PIVLSLFTYD -NKDQDNEGEVLMAHLAKTIVDKw ->[subseq from] Beta-lactamase class A n=1 Tax=Gordonia sp. KTR9 TaxID=337191 RepID=J9REM7_9ACTN ---------RETFTDAGCSGCVHARTIGTPVEF-SHDADAPVVLASVYKLAVLISLCRLAD -RGDIDLAASITVEPTRWAQGPTGLALFTDPVMTWRDLATSMMTVSDNVAADVILTHI-GL -PRIHADLNQLGLTHTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAASCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAIAVFTMS -ARSELPEVDRAIGEVARAVVT-- ->[subseq from] serine hydrolase n=1 Tax=Senegalia massiliensis TaxID=1720316 RepID=UPI00102FA12E --------LESIINEDKLKYSLYVEDLKTNKIIfDINSDAEVTSASMIKIFIMAEAYSQIS -KDEFMSQKIVNVDRDNIVGGSLIKN-LSNYCYSIKDLIFLMMNLSDNTATNQLIDIL-RI -ENINKFISEEGLKNTVINRKMMDFERK-KKGFDNITSSRDIAHILKKIYYKDLIDKDASV -NMMNIMKKQMDNRMMARNIDKSNTKIYHKTGNIPY-TNHDAGIVIFKDIE-YLF-VMLTW -DAYDNIYGRKVIGEVSEKIYNDf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 4R-3d TaxID=2559605 RepID=A0A4Y8Y1N1_9ACTN -----RDRIRAAFAAAGVTGWLHAVDIDSAAQI-EVGADQPVVTASVHKLCLLVALHQHAE -AGRLALTDRVESPAGGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAAELLLARV-GL -DAVNETTERLGLTRTHAVQTFGEFITALDPARTNRSTPRDMTRLLGAIWRDEACTPEHSA -AVRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAVFTRA -ASAALPAADAVIGTTARIAID-- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus aryabhattai TaxID=412384 RepID=A0A2C5HKL9_9BACI -----------------SNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIGAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNELISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-TYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. (strain ATCC 39116 / 75iv2) TaxID=385957 RepID=UPI0002E7C7C9 -------------EAAGVRGWLHARCLDCGGET-GHHPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVTAADRLGGTGTAGCADDVEMSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLADTRVIGSPRDVVAALDPLRTSASTPRDMTTLLAAITGDTAGPPEACG -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPGGERYAVAVFTKA -PTSRLPDVDHAIGEAAKAAIE-- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. AM43-5AT TaxID=2302957 RepID=A0A3A6EC57_9FIRM ---TLEKRIAAELYCYQGKMSVFVDDL-QGHTV-EVGADEEFETASTIKAFILAALYLQTQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFAHTVLHNPLHF-DR---YRRLGTTTPRDYAALFARIAKGELVSREASA -EMLAILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=A0A1U9R0C9_STRNV ------DRIRAAFADAGVTGWLHAADIDSGAQI-DVGADRSVVTASVHKLCLLVALHEHAE -TGRLNLTDQTECPRDGRTAGPTGLSAMLDPALSLRDAAYLMMAVSDNTAADLLLERV-GL -DAVNGTTERLGLTRTHAVQSFRDFIAALDPGRTNHSTPRDMTRLLGAIWRDEACVPEHGA -AVRRLLALQVW-PHRLASGFPDDVHVAGKTGSAPT-LRNEVGVIEYPDRGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01375 TaxID=2203194 RepID=UPI000F77045F ------AEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTAREITTLLDAIWTDRAGDPAACE -RVRAIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA -ESDRLPAVDSAIGEAARLAVAH- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=A0A5P9PY03_9PSEU -----------HFEAAGVRGWLHARRLDTGAEC-GWGADEPVVLASVVKVPLVLEFARQVA -AGQLDPRDRVRIGARDRLGGSGTAGCADDVELSLRDAAYFAMTVSDNTAADVLCDRV-GL -DNVRSLVRELGLARTRIAGAPRDIVAALDPGWTNASTPREMTALLGHLWTDQG---EPAA -QVRQWMGQQVF-WSRLGGAFPPEARVWGKTGTLPC-IRNEIGVVEYPDGARFAVAVFTRS -ALQRQPAVEQAIGAAAAAAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 06738 TaxID=2203210 RepID=A0A3Q8URG6_9ACTN -hrTARSRIRRAFAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTAAVEVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAGRLAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus hammesii DSM 16381 TaxID=1423753 RepID=A0A0R1UQM2_9LACO ---AVESDITTAFKSLDGTNSAYVSPVNGQQQV--VVNNGAQSSASSIKVFILVTAYAMAK -EGVFNLNATHTLTASEKVGGTGVIQNMSDGTLTYREILKHMIDDSDNTGANIMIAKMGGF -GLINNKIKNMGATDTKLQRKMMDTD-AIDQGRDNLTSARDLGMTLKKLYNHQLVSKSADD -EMLAILADNQN-RTKLPKLLPSSAKVYNKTGEYDYGVQNDAEIVANRHGA-FVAVVLSQD -GHEA--DQVAA------------ ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora costi TaxID=1530042 RepID=A0A3B0AEG0_9ACTN ----VEERIGTIFGRAGVSANLHVVDLDDGREV-AVRADEQVVIASIFKILLVLEFARQVA -AGQLDPTERVLVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVVGGPRQLVEVFDPEQTTSSTAREITRLLGLVWRDEAGPPEACA -LVRGWMARQLF-WTRLAAGFPAGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART -EQLDTRRVDLAMGEAARTAV--- ->[subseq from] hypothetical protein n=1 Tax=Heliobacillus mobilis TaxID=28064 RepID=UPI0012D73891 ----LKQRIKKEMADFSGSFAVYLEDLSTGHQF-GINSNMAFPAASVIKVPLVLFLYSLAL -DGRINLDETISIVPSDLEPPGGLWSYNIGTTYTLRQLAKHTIEDSDNTAANMLMRRL-GR -TNFYLFLRLSGASVIPW---GP--------GKGNVTCARDAALYLKGIWLFRQIEHPLGE -EMMQYLLHSKF-DDRIPAGVPFDVEVANKIGSQE-GVFNDTAIIFLPNR-PYVLSVLCCH -PD--EQQAVEAIGRIARLTYEY- ->[subseq from] Serine hydrolase n=2 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4V474_9ACTN -------QAREALAAAGATGTFHARHVGGGAEL-ALDADAVQVAASTYKVAVLLEVACQAV -AGELSLTRRVRVPGDVRSPPSGISSMLDEVELSVRDLALLMMQVSDNTATDVLQEIV-GT -ARIAARLDALGIRDTTVRLDCAGLIAALAGTTGNTTTARDMTTLLSLIWRDEAGPPEACE -EVRRVMLQQYA-PHRLSTAYRDGPKIAGKTGTFYGGVRNEVGVVDFGDGEEYAVAIFLRQ -HELRDGRADAAIGAVARLLVDH- ->[subseq from] serine hydrolase n=1 Tax=Nocardia lijiangensis TaxID=299618 RepID=UPI00083599A4 -----EERIREIFAELPVRGRLHAVDLADGREL-GVGADDQVVIASIFKILLILEFSRQVD -AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFMMSVSDNTAADLLLRRI-GP -DTPALLAAELGLASTRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWRDEAGSPAACA -ATRDLLRRQMF-WTRLAAGFPDEVLVASKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAHS -DETRRIDVDLAMARSARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Acetobacter senegalensis TaxID=446692 RepID=UPI00128D6033 ----LAQSISKSVKAQPGHFAVYAALSGRSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPQDTITVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -LPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGKHYILVVLTSD -LP-DEQAGIKVLNTLSHQTYTYf ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6JFB7_9BACT --kKLQARVDEIAERFDGVTGVAIVDLTDDRAI-LKNTDHVFPTASSIKIAILLELYRQEQ -AGKAKLDDSYTFDAKDLVDGSQIMTGLTPRVLTNRDLAQFVVAVSDNAAANVLIDRV-AM -QNVNATLRNLGLTKTMLRRKMMDIAAAKRG-DENVSTPQEMTRLLQAIYQGKALDKELAE -AFMKQLSTKKE--SYIPRRLPPDVPVAN-------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. or43 TaxID=2478957 RepID=A0A652LSQ5_9ACTN ---------------AGVRGWLHVAELHRSAGV-TIDPDVRLPMGSVYKVPLMVAFCRLAD -ADLIDPRRRLTLDPADRVPPTGVSLLRDPVTMSLRDLVAQMMSISDNAAAAAVLREV-GA -DAVDAMCQELGMPGTHIHGGVVSTFSVYDPAYKASSTASDMARLLRAIWTGQAASEDSCA -FMREVMRSQPW-THRLASGFPDDVTVYGKTGTFG-ALRHEAGVVELADGSAYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter dolens TaxID=1287738 RepID=UPI000A42E3E3 --qHVDAALAPLLAATPARVSLSLRDLDGGIVL-AHHADRVQPSASIIKVPILLALLEAVA -KGRYALEQPLALPATERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ-509 TaxID=444103 RepID=UPI00099CB6FB -hrTARSRIRRVFAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTAAVDVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAGRLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. H219 TaxID=2492662 RepID=A0A426K0R6_9PSEU --------------EFPGRVGIASWDLDEGVPV-LRCPEVEVHSASTIKVLVMITALRAVA -EGRLDLDRVVPLPAS-RTRGTGVLFEIPSVPMSLRDLINLMIVVSDNAATNAVIDEV-GF -PAIAACTAGLGCTGTRVERHIMDTA--APGV--LQTTALDQARVMAALARGEALPPEQTR -HALAVLSRQQV-VDRIPLRLPEDARCWNKTGEIK-GLRHDVALLSADDTPRVVLAVLVDQ -LTDP------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TM32 TaxID=1652669 RepID=A0A4Q1RW54_9ACTN ----TQDHIRTAFADAAVTGWLHACDIDTGAEV-GLHPDHPVVTASVHKLCLLVALHQRAA -QGDFDLTDQIEVPPTGRTFGRTGLGAMLDPAMSLRDAAYLMMSVSDNIAADLLLERV-GL -DAVNRTTTQLGLAHTLAVHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA -AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Pedosphaera sp. TaxID=2024890 RepID=A0A2D8UVD1_9BACT --hDLEQTLRIAIESFQGEVGVYVRKLDGGCEV-AIGADELYPTASLIKVPIVMALLDKVE -VGQLDWNRPIXYRTSQRSTGEDLMAKFKDGSISLDKLIFLTQSVSDNTAARLAQDLAGGG -AAINRWLASNQWLHTRVNARVDGRSPFYDQYGWGQTTPREMAEMFIALRQRRAISPHADE -YLDRMLGKAYW-DDEALSAIPSDVHVISKQGAIN-ASRSEVLLVSAPSG-PYVLCVITRN -QTGDDNEGFQLLRQLSRLVWN-- ->[subseq from] Serine hydrolase n=2 Tax=Actinobacteria TaxID=1760 RepID=A0A329QFI7_9ACTN -----ADRIQRCFDDAGILGSVHAIALHDHGEI-GVLSDEPAVLASVYKLPLAVAYARMVD -AGRLDPRATVMLDPETRTHGATGFAAMTDPVVTWRDAVRSMMAVSDNAAADALLDVV-GI -TRLADVLDDLGLASTRITGGIRDLYAFDPANPHNSITCRDMTRLLSSLWTDRAASPEQCE -FLRTIMAQQVW-TQRISAGFPDDVIVAGKTGTFV-GLRHEAGVVEYPNGEAYAVAVFTTS -TRARLPAAETAIAQAAKLAVAH- ->[subseq from] Uncharacterized protein n=1 Tax=Solitalea canadensis (strain ATCC 29591 / DSM 3403 / NBRC 15130 / NCIMB 12057 / USAM 9D) TaxID=929556 RepID=H8KVC5_SOLCM --kKLNGELQELVKGFNGTVGIYVKNLKTGKTA-AFNADTIFPTASMIKVPITIGLFNKIN -KGELKYDSVLTYKDSLLYEGEDILGSFKNNEVALSKVAMLMITTSDNTASLWCQSMAGKG -TTINEWLGTNGFQYTRVNSRTPGREANRKLYGWGQTTPLEMAELLVRIRRNEVISPAISE -RIYRNLIRIYF-DGEALSQIPPYIQVASKQGAVDQ-SRSEVVLVNAPHGD-YVFCIITKN -QKDENNEGYVLIRKLSALLWNYf ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis thermoflava TaxID=84480 RepID=UPI000419DDD8 --------------AAGVRGWLHARCLDCDGET-GHHPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVTAADRLGGTGTAGCADDVEMSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLADTRVIGSPRDVVAALDPLRTSASTPRDMTTLLAAIAGDTAGPPEACH -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPGGQRYAVAVFTKA -PTSRLPDVDHAIGEAAKAAIE-- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. HAJB-30 TaxID=2715536 RepID=UPI00140B3CB2 -----TTRLENTFADAGVTGYLHAVDIDSGAEV-GLAPDTPVVTASVFKIYILLELCCRSA -EGSLGLTDRIRIPAGDRSLGPTGLSVMLDDTLSLRDAAYLMMSVSDNHATDVLMDFL-GV -QAINDRLRTLGLEQTVAMYSCDALFRALDPEQTDRSTPRETTALLTELWRPRTLPEEACA -EARRIMGLQVW-PHRLTSGFPDDITVSGKTGTLSH-VRNEVGVVEYPDGGRYAVAVYLRL -PGRENPVADAVIGRAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=A0A354KMV4_9FIRM -------------KSIDGDVSFYYKNLTTNNTV-AYNEEKIMLAASVIKLTVLVEAFKQIK -EGKIKKEEIFITCEDDKVPSCGALNYMREGLVTLEDLYVLMIILSDNYATNMLIDKL-GM -DNINNTIKEIGLRNTVLNRKMFDSKKS-ALGLENYISASDVGYLLEKMYNKDLIDEKSSE -EMINILKNQRL-NGKIPHNLKPKIDIAHKTGEDTN-TTHDVGIVFAK--EPFIICFCGNN -VN--VPEYERLIQDITYDLY--- ->[subseq from] serine hydrolase n=1 Tax=Cupriavidus malaysiensis TaxID=367825 RepID=UPI000A6EFD4A ---RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG -QDRLRLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALIALL-GF -DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGRDNFTSAGDTAAALGWLLRGDTLPAPLRA -FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG -FTDPRTARE-------------- ->[subseq from] serine hydrolase n=2 Tax=Veillonella sp. CHU110 TaxID=2490947 RepID=UPI000F8F278F ---KARQKLSQISDSIQLAPYESVYIGYHGESV--VKQSKPMRAASMIKVYILGYLFEEVE -AGRISLDETILLQRSDQVGGAGILSGYSGTALTIDELAKLMITISDNTATNILIHRL-GI -ENINTYIVKHRYADTKLQRNMMDLT-AIEEGRENYTSAKDLGTWFMNLLDGKNMSGASRE -KMLTYLLGQTD-TETFNEALP-NRSIAHKTGELG-GVYHDGGIIFQNN------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Pseudopedobacter saltans TaxID=151895 RepID=A0A2W5ETQ7_9SPHI --tKLEKKLKPLLDSFHGVSAIYVENIKTGKIV-AINADTIFPTASIVKVPILTAVYSQIN -AGKLQYNQPLIYKDSLKYGGSGLMQFFKDSSTDLSTAAALMIDYSDNTTSLWLQLLVGGS -DKVNDVMESIGLHNTRDNRTNREAFRSIYG--WGQTTPREMATLLKLIFQKKILTPSSCE -SMYRTMSHVYY-DNFSLSQIPPYVQTASKQGMVDD-SRSELVLVNAPHGD-YVFYIATKK -NKDQDNEAWELQRKISSILWNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces indicus TaxID=417292 RepID=A0A1G9GJM8_9ACTN ----------------------------DAAEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAHDRLGGWGTAGCADDIEVSLRDLAYFALSVSDNTAADLLLARV-GP -DTVQLLAKELGLDRTRIVGGPREALAVLDPQRTNSATPREITRLLRLVWRDEAGPAQACA -LVRQLMSRQVF-RHRMVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGGSYAVSVFART -REAARTAVDSAIGATARIAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Saccharopolyspora TaxID=1835 RepID=A0A1H6EMA2_SACHI ----VERRIREVLADAGAEGWVHATQFGGGREI-CLGADELVVTASVYKLPLLVAMCRAFD -AGRLDPRATVRIDPTSCTPPSGFSTFLDPVTVSWRDLAASMIAVSDNSAADVILGAV-GL -DAVADVLADLGLTRTRVVGGTADQHAAYDPAYASATTPREMTRLLELIWTDAVASPQQCA -FIRRLLGNQIW-LHRVRSGFPQGVRVAGKTGTVG-AVRNEVSVVEFEGEEPVAVAVFTLA -ARADLPRVDTAIGECA------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. GZWMJZ-114 TaxID=2494734 RepID=UPI001013A724 ---AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEAHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V5RE43_9BACT ------------------------------------------------------------- -----KLDDIYTFDPKDLVEDSQIMAGLTPAVVTNRDLAQFMVAVSDNAATNVLIDRV-GM -QNANATLRSLGLTKTMLRRKMIDIAAARRG-DENVATSQEMTRLLEIIYKGKALNKEVTD -QFIKQLKTLKK-DSYLSYELPADVELADKPGSLD-GIRNDSGIIFAPNR-PFAITVMTAY -DR-DEKAAERAIGQVALEAFHYf ->[subseq from] serine hydrolase n=1 Tax=Cellulophaga sp. BC115SP TaxID=2683263 RepID=UPI001411F924 --kALEKKLQVLVNNFQGVAGIYVKHLKKNTGV-AIQADTVFPTASMIKVPITIGLFNKIE -KGELDYHAILTYKDSLLYAGEDILGSFKDGEIALSKVAMLMITTSDNTASLWCQAMATG- -TAINEWLAANGFENTRVNSRTAGRESYRKIYGWGQTTPREMAELLVKIRKGEVINPAASE -RIYRNMVRIYW-DGEALSQIPPTIQVASKQGAVNQ-SRSEVFLVNAPSGD-YVVCVTTKN -QKDENNEGYQLLRNVSKIVWEHy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A5H2US86_9ACTN ------ARIAAAFTGAGVTGWLHARDIDTGAEV-DAGADRPVVTASVHKLCVLVALHEAAA -AGRLDLTEQTEIPAHGRTPGPTGLGSMLDGALSLRDAAFLMMSVSDNAAADVLLERV-GL -DAVNATTRRLGMPRTEAVETFGSFLGALDPARTNRSTPRDMTTLLAAVWRDEAGAPDHCA -AMRRILGLQVW-PHRLASGFPDDVQVAGKTGSAPT-LRNEVGVVAYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI000467EB95 ---ATRRRITAAFADAGVTGQLHAADIDTGTAL-GVGSDTLVPTASVHKLCLVATLYRQAS -LGLVDPTRPVDIPAAGRAPGATGLSAMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNATMTGLGLTRTHAVQTMRELLAALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE -ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRNEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAAIGAAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Microlunatus speluncae TaxID=2594267 RepID=UPI00137580A2 ---------------GPATVSVTLLD-DHGDTVaEVNPDAQHYAASTMKLPLVLAAYRLAA -AGKLDLDAELPVHNEFTSQGTPFGWDRLGGTATLRWLCQRSVVRSSNLATNLVLDQV-GL -PAVAEAIATCGATGVSVGRGINDYAARDRLGDRNLITTRGLATILSALHHGTAADRTTCD -AVLAVLAANEV-ATDLRAGLPPGTWVAHKNGWVTD-VVHDAGLIRPPDARPFVLAVATTA -PWP-GEVAHAFIASIAAAVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A522R577_9BACT --rKLTEKLQKVVDSFHGTAGVYVLNLKTHQEA-AINADTLFPTASIIKVPIIVAIFKKIE -DGQLNYHQPLLYRDSLAHGGSGIMQYFKDSTTNLSVAVTLMISHSDNTAAHWCQTLAGGG -AAINVWLENHGFQYTRDNSQTPGREDADNLYGWGQTTPREMAHLLLLIRENKIITPAACE -RMYRDMTHIFW-DDYALSQIPPYVQTASKQGMVD-ASRSELVMVNAPKGD-YVFYVATKN -NKKPDNEAWQFARNVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Pararcticibacter tournemirensis TaxID=699437 RepID=A0A4Q0M5L9_9SPHI --kKLTALLQDAAKGFDGTVGIYVQNLKTNKTA-AINADTLFPTASMIKVSILCGVMDKIE -KGELLYNQKLVYRDSLLYPGVDILGSFKDNEIDLSKVAMLMITMSDNTASLWLQKLVSG- -TYINNWLDQNGFKVMRVNSRVEGREPARKIYGWGVTTPYEMCRLFTLIRNGKVVSPAASE -RIYRNLVRIYW-DEGALSQIPPYVQAASKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN -NKAETNQAHQLIRRISSLLWHYf ->[subseq from] serine hydrolase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A390ED6 ----LAHQIEKTVQGQKGLFAVYAARVGATPEV-CLNCDHLINAASTIKLFVLDAAYKAFA -SGTLHPTDLIRVHNHSLVGKGTFAYAQQGKEVPVSELLRVMIQYSSNLATNLMIEKL-GV -FPIRDVVKEQALDGIVFGRMIEDFDAD-AQNIRNRVSARGLGEFLQKLDQGQIVGKEASQ -SMIAIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVKNDAAIITLPDGAHYILVVLTSG -LP-DEAAGVKILNVISREVYDYf ->[subseq from] Serine hydrolase n=2 Tax=Streptomyces sp. A1499 TaxID=2563104 RepID=A0A4S3GPW1_9ACTN ---DVQRAIRGMFADAGVRGWLHVAELHREARV-TVDPDEPVPVGSVYKVPLMAAFCRLAD -AGALDPRQPVTLGPDERMPRTGISILRDPITVSLRDLVVLMMSVSDNTSADAVLRHV-GP -AAVVELCRDLGLPDTHILGGAATTFEVYNPLSKASSTPSDMARLLRAIWTDGAASAESCA -FMRETMGQQAW-SHRLASGFPDDVTVSGKTGTFGT-MRHEAGVVELPDGGVYTAVVFTQA -ARADLPRADAVIGTAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154MRL7_9PSEU -------EIEAVFANAGARGFVHAREVGGGPEV-AVGADDPVVLASVFKIPVAVAFAREVA -AGRLDETERTRVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRI-GQ -AAIDQVLTDLDLTRTRLIGCCEDLFAVVDPERTTSSTPREITTLLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPAEVAIAAKTGTLPS-VRNEAGVVTHVDGRRFAVAVFTRA -DSLDLPAVDSAIGEAARLAVEH- ->[subseq from] Serine hydrolase n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A3D0XIZ2_9BACT --hDLEQTLRIAIESFQGEVGVYVRKLDGGCEV-AIGADELYPTASLIKVPIVMALLDKVE -VGQLDWNRPIVYRTSQRSTGEDLMAKFKDGSISLDKLIFLTQSVSDNTAARLAQDLAGGG -AAINRWLASNQWLHTRVNARVDGRSPFYDQYGWGQTTPREMAEMFIALRQRRAISPHADE -YLDRMLGKAYW-DDEALSAIPSDVHVISKQGAIN-ASRSEVLLVSAPSG-PYVLCVITRN -QTGDDNEGFQLLRQLSRLVWN-- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. LD22 TaxID=2650748 RepID=UPI00124EF25B -------------RDAGVTGFLHAADIDTGREV-AVAADAPVVLASVFKVPLLVAFHRLAA -QGRLDPTEQVTLAAGDRTSPTGVSALLDDVRMSLRDLACLMITVSDNAAADALLERV-GL -EAVNAAAEGLGLRATVVTGGGRQLFDALDPSRTSRSTPRDMTRLLAAIWRDEAAPPDGCA -AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLLT-VRNEVGVVEYPDGGRYAVAVFTRS -LLAVLPQADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces olivoreticuli TaxID=68246 RepID=UPI000E24A231 -----LARIRDAFDAAGVTGRLHALDIDSGAEI-NAGADLPVVTASVHKLCLLVALHQRAA -AGHVDLTEQIECPPAGRTLGPTGLAAMLDPVMSLRDAAYLMMAVSDNTSADILLERV-GL -DAVNDTTARLGLTHTHAVHTFGRILAALDPARTNRSTPRDMTRLLAAVWRDEACAPEHCA -AVRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAVAVFTRA -ASATLPPADAVIGTTARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Cupriavidus sp. USMAA2-4 TaxID=876364 RepID=A0A1D9HBH7_9BURK ---RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG -QDRLRLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALIALL-GF -DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGSDNFTSAGDTAAALGWLLRGDTLPAPLRA -FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG -FTDPRTARE-------------- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. YM53 TaxID=1572659 RepID=A0A4R0JZE9_9ACTN ------ARIRAVFEDAGVRGWLHAVALDAPEATvDVDADTVVPMASVYKVPLLAGFCRLVD -LGEVDPRRQLTLDPSTRTAPTGVSILADPVTMSLRDLAVSMITVSDNASADALLDVV-GL -QRLAELLESFGLKRTWVRRGTAGNLRVYEAANASASSPRDLTTLLRRLWTGELLSEQQTA -FVRATMHRQLF-MHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Uncharacterized protein n=2 Tax=root TaxID=1 RepID=A0A2E7QRB3_9CHLR --eQLNERIGEMIYTFPGIAGCCVKSMTDGNII-SVNGDVEFPIASTIKIPILLQLLVLDE -KGELDINELIDITPEMIYPGSGIISYLEGPVLSILDIAILMIIVSDNTSTNLCIDYA-GI -DKTNDMLRSLGVDNITLRRKMQDTESV-VANRENVGTPDDCVLLLEHLYNGRP-TQNSAD -RCLSILRKPKR--SILNRFIPTETPLANKPGGMAR-VRCDAGIVYLSQY-PYAVSIQTSF -SEIEPEDQENFIVELGSMI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. TverLS-915 TaxID=1839763 RepID=A0A1C4KZ71_9ACTN ---AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPAAHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIAVD-- ->[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces sp. (strain SPB78) TaxID=591157 RepID=D9UTF0_STRS3 ---AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPAAHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A4P5WFL1_9BACT ---------DAELVRFPGKAGVWVKHLTTGEEA-GVHAHDTFNTASVIKIPVLVLAMQLAD -QGSLSLSERITIGASEMRGGSGIFRYDPGLQPTFRDVLTQMIITSDNTATDIAIGKTGGV -DAVNRWLVASGYGGTKLSMTTADLFATDRSYWLGEMTPHATGRMLEAIQRCHVASKAACA -DMMRMMRGQQSGARRLPHFLN--VPVAHKTGDFPPALANDVGVIFTRSG-PVVVAFFANA -IEGPYADAEDRIGQIAQRIVDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ289 TaxID=2572907 RepID=A0A559UVY7_9ACTN -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRIDLTAAVDVPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARVAVD-- ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Shapirobacteria TaxID=1752721 RepID=A0A2M6YQK0_9BACT ---SVLDQIQSLTKDLRGKYGVYVYELDDKNQY-GVYQNEKFPAASLMKLPVMLLFYQELE -EGKIDPEAKYTLKENDKVLGAGILQKSVGTVYTYRQLVEYLGQYSDNTAFKVMRQIL-GD -EKIQQTIDDLGMTKTSLEDFE--------------TSPTDIGLFFQKLYQGKIITTENRL -ELLDFLTKTAY-EDWLPAGMSKKIKVAHKIGRDT-GTFSDAGIVFAD--KPYIIVIMSKK -ARE--IEANEVLPKISSLVWD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI0012B90BED ----------------RSNNGLIRIHIEGKESI-QINSFIQQRAASTIKLLLAIEAFRQID -EGILALTSVIQRMEKNTVGGAGVLRALPRLTIKVEELLTLMIMVSDNTATNEIISLV-GF -EKINECAKNLGLKKTVLNRYMMD-ETAVKQGIDNYTCASDVVKCLKEICEGNFLRKSSCE -KIMRMLEMQQF-RHKLPARIGSAFQAANKTGELQ-GAEHDSAILMRGNE-MYYAVVLIDG -LS-DNEQGRRLITDIGYL----- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. S4.7 TaxID=2705439 RepID=A0A6C0Q333_9ACTN ---------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQVV -AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GL -DTVQALARQLGLERARVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA -GVRELMSGQVN-GARLGAAFDRFTTVAAKSGTLP-GIRNEIGVVTYPDGARYAVAVFTRT -ASTRRPDLDAAIGGAGREAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=A0A1Q5K1L9_9ACTN -------ALSSTFTQAKVEGTVHVRDLDTGAEF-AHAADTPVVLASVFKIPIALEYARQAA -SGELDPARRHSVTSAYRAGGSGTDGCAHDVEMSARDLAFMMMTISDNAATDLLLDIV-GP -DRVRATLDGLGLPGFGFSSCS-ALDDACTPGTSPSSTPREVTALLAAIWHDEAGPARACA -EVREIMRAQVW-QHRLVSGFPPGVRLAGKTGTDFS-VRNEAGVIEYPDGKRYAVGVFLRT -STTRQPLADRAIGRAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora hirsuta TaxID=1837 RepID=A0A5M7BE95_SACHI ----VERRIREVLADAGAEGWVHATQFGGGREI-CAGADELVVTASVYKLPLLVALCRAFD -AGRLDPRAAVRIDPTSCTPPSGFSTFLDPVTVSWRDLAASMMAVSDNSAADVILGAV-GL -DAVAEVLDDLGLSRTRIVGGTADQHAAYDPAYASATTPREMTRLLELIWTDAVASPQQCA -FIRRLMGNQIW-MHRVRSGFPQGVQVAGKTGTVG-AVRNEVSVVQFEGEEPVAVAVFTLA -ARADSA----------------- ->[subseq from] serine hydrolase n=1 Tax=Actinomadura sp. NEAU-AAG5 TaxID=2678616 RepID=UPI0012E295B5 ----------------------HAADIDTGREV-GLRADAPVVLASVFKVPLLVAFYRQVA -DGVLDPTEQLTLRPQDRTAGPTGLSALLDEVVSLRDLACLMIAVSDNASADVLLERV-GL -DAVNAAAADLGLRRTRVEGSGRDLFEALDPVLTSRSTPREMTRLLGAVWRDEAAPAAECA -AMRRLFGLQVW-PHRLSSGFPDDVVVSGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -LLAVLPQADAVIGTSARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Gordonia sp. HS-NH1 TaxID=1435068 RepID=UPI0006E31274 ---------RETFTDAGCSGCVHARTIGTPVEF-SHDADAPVVLASVYKLAVLISLCRLAD -RGDIDLAASITVEPTRWAPGPTGLALFTDPVMTWRDLATSMMTVSDNVAADVILTHI-GL -PRIHADLNQLGLAHTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAASCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAVAVFTMS -ARSELPEVDRAIGEVARAVVT-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. MKU004 TaxID=1849370 RepID=UPI0009EDFC4C ----LERQIHELVEGVEGRISLNIEL--PAHTI-QLHSDVPYSAASLIKLPILLEGFRQIQ -ERKLDPEEVIPVTQEDKVGGAGVLSHLSPHTVTVHELLTLMIIVSDNTASNLLIDRM-GM -DSINGMCRLLGLEQTKLNRRLMDFE-ALESGVDNHISATDAVKCLKGMENEVLFQLSSRE -SMIRILENQQF-YQKLPGSMDNRVFTANKTGELP-GVEHDCAIIRYNQK-TVYAAVLIDE -LK-DSSEGSGLIMKVGKCLND-- ->[subseq from] Serine hydrolase n=1 Tax=Kitasatospora sp. MMS16-CNU292 TaxID=2567942 RepID=A0A540WGM1_9ACTN ----ARARIAEAFAEAGVTGLLHARDLDTGTEL-AHGADTLVSTASVHKLCVLTTLFRQAA -AGRIDLTRRLDIPAFGRTDPTGLAAMLDAARLSLRDLAYLSIAVSDNTAADLLWDEL-GL -DAVNGTMADLGLTRTVAVHKIRDMIAVLDPAFTNRSTAREMTALLAAIWYDQACPGEHGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVIEYPDGGRYAVAVFTRA -TATSLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis taiwanensis TaxID=342230 RepID=UPI00048936BF -----EREITARADELGLRVRMHATDIDGTASF-GISSAEPVVTASVFKVPVAVELARQAV -AGECDLAEQVTVPAGPKVPYGLATFRH-PATLSLDALATLMIGISDNVATDLVFARV-GK -PAVRSLLDRLGLTATVIDQDCAELLAALQPDQTCRTTPEDMTRLLGMIWRDEAAPPQACA -EVRRWLGLQVW-PHRLRSGFHDDVRISGKTGTLPT-IRNEVGVVEYDDGGRFAVAVFTEA -VDAQAPERDAFIGFAAARAI--- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. YIM 10 TaxID=2653857 RepID=UPI00129079FE -------------EAAGVRGWLHARRLDTGAEC-GWGADEPVVLASVVKVPLVLEFARQVA -AGQLDPRDRVRIGARDRLGGSGTAGCADDVELSLRDAAYFAMTVSDNTAADVLCDRV-GL -DNVRSLVRELGLARTRIAGAPRDIVAALDPGWTNASTPREMTALLGHLWTDQG---EPAA -QVRQWMGQQVF-WSRLGGAFPPEARVWGKTGTLPC-IRNEIGVVEYPDGARFAVAVFTRS -ALQRQPAVEQAIGAAAAAAV--- ->[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum hinesii TaxID=2290915 RepID=A0A398DSJ9_9BACT --qDWQEQVRVLLDGAQGKFGVYAA-TPTVPLF-EYQASSIFPSASTIKVLIMAELLRQVE -AGTHALTEHP-VLPTAPTGGCGILEFLSSDYPDLMDLLHFMICSSDNKATNVLIHLT-GI -DAVNQLAVDIGMTNTRLRRFMMDTES-IQQDIDNTTSPADMGRFFKLLACNELVSSKASA -TMKTILGHQQF-ADIMMLFLPEGIRAEHKTGGLP-GSVLDVGLVYGA-RDPLILCLMATQ -LAN-NGEGAIILGKVAAIAYT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis saalfeldensis TaxID=394193 RepID=A0A1H8XGH4_9PSEU ------EEIEAVFAGAGAQGFVHAREVGDGPEV-GVGADAPVVLASVFKIPVALAYAREVV -AGRLDETERTRVTARYRIGGIGTAGSADDVEMTWRDLARFMLTMSDNAATDVVFHRV-GQ -AAVDRVLSDLGLSRTRLIGCCEDLFAALDPERTTSSTPREITTLLDAVWTDRAGEPAACE -KVRAIMAQQIW-PHRISSGFPSGVTIAAKTGTLP-AIRNEAGVVTYADGRRFAVAVFTRA -ASDRLPAVDRSIGEAARLAVG-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0003321813 --qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Catalinimonas alkaloidigena TaxID=1075417 RepID=A0A1G9BA37_9BACT --kKLQAQLEQLVAGFRGDVGIYVRHLKTGRTA-MIHADSLFPTASMIKIPITIALFDKIN -RGELDYHTPLVYRDSLLYPGEDILGSFQDSAIELSKVAMLMITTSDNTASLWAQSLAGTG -TVINQWLADHGFRHTRVNSRTPGREPNRTHYGWGQTTPREMAELLVMIREGRVINPAASE -RIYRNLCHIYW-DHEALSQIPPTVQAASKQGAVDE-SRSEVVLVNAPSGD-YVFCVITNH -QQQQDNEGYVLLRDVSCLLWQYf ->[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus phasianinus TaxID=2017483 RepID=A0A220U1Q5_9BACI -----EATIHELLKDIIDHFSIYIQT--SDGDI-SINAFEPKRAASTIKLPILIEAFRQIE -AGNLQPDTLVYIETDMKTGGAGVIDYLTNSNYSYRNLLELMIIVSDNTAANIILDKI-GM -DTVNELAAAIGCNHTILSRKFMQLKDP---SLENYTSAQDMVKFLHLMEEDDLLSETSRN -EIKQIMGHQQN-NCKIAHYMNHDIKVYHKTGELT-GIEHDVALLTYQEQK-VYLALLSEN -WQN-NGTGRDYLAAIGKIVLQY- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter rubeus TaxID=2027860 RepID=A0A5C1I876_9SPHI ---KLTAKLNDAVKDFHGQVGIYVHNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GS -EYINNWLDQNGFKVMRVNSRAPGREAMRKIYGWGVSTPREMCRLFTLIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHDD-YVFSIITNH -NKTPNNEAGLLIKKVSALLWHYf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A177G240_9PROT ----LAQIMAETVKNQPGHFAVYAARSGQPPDV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPEDTLTVHNHSLVGGSFALYAQAGKAVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRAIVKAQGLNGVVFGRMIEDFDAN-DQGIRNRVSARGLGTFLQKLDNGKIVGKTQSQ -SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVQ-GVRNDAALVTLPDGKRYILVVLTSG -LP-DEQAGIRVLNTLSHQAYAYf ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI001231E3E6 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] hypothetical protein n=1 Tax=Bacteroidales TaxID=171549 RepID=UPI0012AF0272 --------------------------IKDGQFY-GIHENNYFPMNSVMKFPQALFVADWMQ -RNNIRLSDSVKVTKEELIEWSPKLGDIQTSKFTYAELLSYSLMLSDNNACDVLFKRCGDP -KTVEAYIRKLGFKRIHIRKTERQMREDHSCCRYNKATPKDMTLLLQWFSSHNS-DTPILQ -FIWETMMKCETGMDRLPAANPEGAALLHKTGSGYTTDIGDAGIYLLSDGSKWPICVFVKG -ASTN------------------- ->[subseq from] Serine hydrolase n=1 Tax=Jiangella anatolica TaxID=2670374 RepID=A0A2W2CJQ2_9ACTN ----VEGELREAFAAAGVTGFLHAVDVSSGADL-GVDADAPVVTASVFKIPVLVELCRQVA -AGERSPSDRVRIPAGSRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDTLMALL-GR -ERINAGMAALGLPGTVLEEDCAGLFAVLDPLTTNRSTPRETTTLLRRVWTADGLAPAACD -EIRRIMALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYSDGGAYAVAVFLRL -PGSENPEADAVIGTAARIAVEH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. jys28 TaxID=2571125 RepID=A0A4U0P4G1_9ACTN -----PARIHAAFAEAGVTGWLHALDIDSGAQI-DAGADQPACTASVHKLCLLVALHELAA -EGGLDLAEQIECPPAGRTAGPTGLAAMLDPVMSLRDAGYLMMAVSDNAAADLLLRRV-GL -DAVNHAMNRLGLTRTHAVHTFGELFAALDPARTNRSTPRDMTHLLGAVWRDEACTPEHGA -AIRRVLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVAEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Halorussus sp. HD8-83 TaxID=1710537 RepID=UPI00109269F4 ---DLADYVDNYARKLDGRLGVFLRGPDDFEVVyRSRAAETFSSASVIKLPVLYALYEKYD -GRLGGLDRPREIAPENRVAGSGLFHLLSETRPSLQDLARAMIAISDNAATNELIDEV-GI -ERIEQSARDLGMADTRLRRKLMATLGWPEGEPANATTPADCARFFADVLHEATLSSAAYD -RLVVPLEEQKH-ATSFPRYLPFETPIAHKTGSIPT-AALDTGYVSDPDSSPLVFAVFADR -LEH-GRDGSDAIAEIGDAVYA-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. IC4_135 TaxID=2715537 RepID=UPI00141DA505 ------ASIADVCDDANATVAFHVRSLDGKLEI-GSGADARSVTASTYKVPVMLEVAAQAS -EGRLQLADRIKVPADRRTIPSGISAMTDDVEVSVRDLALLMMQVSDNTATDILQEMV-GT -ENIMSRLRSLGLHSTDITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA -EVRRVMGLQFA-PHRLSSAYVDGPAISGKTGTFLAGVRNEVGVVDFGDGDVYVVAIFLRD -KNNHMRKVDAAIGKIAALAI--- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=A0A1H5RFQ3_9PSEU -----------IFEAAGVRGFLHARRLGSSSSV-GVDPDEPVVLASVVKVPLAYEFARQVA -AGLLDPADRVRASAADRLGGSGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV -ANVRSLLSELGLTRTSVIGAPRDLLRALDPLRTSATTPREMTSLLAAMWRD----PGPGA -QVLAWMSAQVS-WHRLTAGFPPEVAVAAKTGTMP-GIRNEIGVVTYPDGGAYAVAVFTAG -GAETRPDIDRAIGDAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536D394_9CHLR ---TLASRLDHALLGVDGQIGVAVKDLGSGRGA-VLNGDLELPAASLYKLPVLYAVFDA-- ---GLRMAEELPITDDALSYDAGTMELGAGEALSVAEALERMITISDNTSAVMLGGRV-GP -SRVNSSIAALGMSTTHYSLTR------------MTTSSLDILHLLDLLARGRAVSPAASA -DMLHLLLRQRV-NDRLPRLLPDAIRVAHKTGNLP-GTVNDVGIVYGPSA-TLAIAVLVSD -TT-DEAAAATGIARVAQAAFAYf ->[subseq from] Beta-lactamase class A n=1 Tax=Spirosoma oryzae TaxID=1469603 RepID=A0A2T0TB94_9BACT ---RLAKSLQQLIGSFHGQAGIYVRNLRTGQTV-AINADTLFPTASTVKIPIQCGLFDKIH -QGELSYEQPLTYRDSLHYDDGIVGSLKDGTTIPLSQVVMLMESVSDNTGSLWCQALAGGG -KTINQWLDANGFRQTRVNSRTPGREAFQKQNGWGQTTPRELADLLVYIRDGKAVSPDASD -EMYRNLGRQYW-DHDGLSQLPPSVKAVTKNGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKH -QQDEDNEGTTLMRTVGALLWHHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=A0A5P2B4Y0_STRVZ --------LREAFAQAGVTGRLHAVDIDSGVEV-DFGADQPVVTASVHKLCLLVTLHQRAA -AGALDLTEQVECPADLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL -DAVNLTTAALGLDRTHATHTFGELLAALDPARGNRSTPRDMTRLLAAVWRDEACAPQHGP -ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ASAILPAADAVIGTASRIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Nonomuraea sp. p1410 TaxID=2603600 RepID=UPI0012F7454B -----------VFAAAGVEGWLHAVDIDSGREC-GYQPDAARPIASVFKVPLLVALCRQAD -QGSLDLGELVRVPVAGRTSPTGLSAMRDEVTISLRDLAYLMIAVSDNASADVLVERV-GL -DTVNAMLAGFGLTGTRVPMSGAQMLDALDPEHTNSGTPRELTRLFAMIWRDEAASPELCA -WMREVFGLQVW-PHRLAAGFPDDVDVSGKTGTLPT-IRNEAGVVEYPDGGRYAVAVFTRS -FSVNQPRADAVIGTAAHMAVDH- ->[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-887 TaxID=2682777 RepID=UPI00140CF8DF ---DIEASLSQLIEDSGASASFAYRYLSSGWDF-SVHGKEPHTAASMISLAVLTQLFDRID -AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM -DAVNSEVARQGLEGTSLERHMMDTEAQ-KEGRENRMAADDAAAILNAIAQGAFYNEELSD -FAYDLLSQQKS-DSAVKGALPEGATYAFKSGSLEN-VYNEGGVVFG--EHPYVFVAFVEG -VD--EEEATALVKDAAALV---- ->[subseq from] Serine hydrolase (Fragment) n=4 Tax=Streptomyces TaxID=1883 RepID=A0A6B1QJ04_9ACTN --------LREAFAQVGVTGRLHAVDIDSGVEV-DFGADQPVVTASVHKLCLLVTLHQRAA -AGALDLTEQVECPADLRTPGPTGLSAMLDPVMSLRDIAFLMMAVSDNTAADLLLARV-GL -DAVNLTTAALGLDRTHATHTFGELLAALDPARGNRSTPRDMTRLLAAVWRDEACAPQHGP -ALRRLLGLQVW-PHRMASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ASAILPAADAVIGTASRIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-126428 TaxID=2073158 RepID=UPI000CD04E78 ---------------VGVRGFLHAHRLGSAEEV-GLDADSPVVLASVVKVPLAFEFARQVA -AGQLDPTDRVRASAADRLGGTGSAGFADDAGYSLRDAALLALSVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTTVIGAPRDVLRALDPLRTSATTPREMTTLLAALWADDVGAP---- --VREWMSAQVS-WHRLTAGFPPEVAVAAKTGTMP-GIRNEIGVATYPDGTAYAVAVFTTG -GAETRPDIDRAIGEAARAAVDQ- ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus profundus TaxID=372463 RepID=A0A417YP77_9BACI ------------------------VVHSTEGTI-QFNANTPRKAASVVKLFILAEVLQQIE -AGRIQREQLISIKPEAMVEGAGVINYLTKHNYSYQNLLELMIIVSDNTASNILLDMI-GI -DRINHSIKKLGCQDTIIKRKFMDQEA-QASGNENITTAADIVHLLKLFSSDNGYSKNLRQ -EVRRLLKNQQF-NNKLAAYQMCKLNIYHKTGELP-GVEHDVAIMESTGRK-LEVAVLTEG -WEN-NGIAQHFIAEVGRYLMNY- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C4D045 --qHVDAALAPLLAATPARISLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus enclensis TaxID=1402860 RepID=A0A1C4BTH9_9BACI ----LERQIHELVEGVEGRISLNIEL--PAHTI-QLHSDVPYSAASLIKLPILLEGFRQIQ -ERKLDPEEVIPVTQEDKVGGAGVLSHLSPHTVTVHDLLTLMIIVSDNTASNLLIDRM-GM -DSINGMCRLLGLEQTKLNRRLMDFE-ALESGVDNHISATDAVKCLKAMENEVLFQLSSRE -SMIRILQNQQF-YQKLPGSIDNRVFTANKTGELP-GVEHDSAIIRYNQK-TVYAAVLIDE -LK-DSSEGSGLIMKVGKCLND-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardiopsis gilva YIM 90087 TaxID=1235441 RepID=A0A223S811_9ACTN -----GERVEDILAEAGVDAQVRVVDIADGREV-AVRADEQVVIASIFKVLLVLEFARQVE -AGQLDPTERVLIGAADRLGGWGTAGCSDDVEMSLRDLAYSAMSVSDNTAADLLMRRV-GL -DIVQILAQELGMRRTRVIGGPRQLLEVLDPAHSTSSTAREVTDLMAMIWRDEAGPARACA -AVREYMHRQIF-WTRLASGFPPEVRVAAKTGTLP-GLHMEAGVAEYPDGGRYAMAVFART -RDTRRIDIDLAMGRAARAAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CMB-StM0423 TaxID=2059884 RepID=A0A2K9EUE8_9ACTN -hrTARSRIRQAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTAAVDVPAEGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDTV-GI -EAVNRAMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRISGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC04770 TaxID=2487423 RepID=A0A429UKF0_9ACTN -----------------GWLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Serine hydrolase n=2 Tax=Verrucomicrobiales TaxID=48461 RepID=A0A353DY23_9BACT --hDLEQTLRIAIESFQGEVGVYVRKLDGGCEV-AIGADELYPTASLIKVPIVMALLDKVE -VGQLDWNRPILYRTSQRSTGEDLMAKFKDGSISLDKLIFLTQSVSDNTAARLAQDLAGGG -AAINRWLASNQWLHTRVNARVDGRSPFYDQYGWGQTTPREMAEMFIALRQRRAISPHADE -YLDRMLGKAYW-DDEALSAIPSDVHVISKQGAIN-ASRSEVLLVSAPSG-PYVLCVITRN -QTGDDNEGFQLLRQLSRLVWN-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. DK17 TaxID=186196 RepID=UPI0002EE34A7 -------------------------------DI-AVGADDLVVLASVYKLPLLVALCRAFE -SGELSPTASVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ASVERTLSELGMTSTRIIGGTADAHRAYDPSYASATTPREMTLLLDAIWTGRAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OK098 TaxID=1855297 RepID=A0A1M7NZY5_9SPHI ---KLTAKLQDAVKGFNGRVGIYVHNLKTDKIA-AINADTLFPTASMIKVSIQCGLMDKIE -KGEMQYNQKLVYRDSLLYKGEDILGSFKDGDIEVSKVALLMITMSDNTASVWLQKLV-GG -DYINNWLDKNGFKVMRVNSHVPGREAIRAKYGWGVTTPYEMCRLFTLIRDGKAVSPGASE -RMYRNMGRIFW-DDKAISQIPPYIQTASKQGALDE-SKSETIMVNAPHGD-YVFSIITSN -NKKPDNEAYLLIKKVSALLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura syzygii TaxID=1427538 RepID=A0A5D0U6F6_9ACTN ---DITERIEGEFKAAGVTGWLHAVDVDTGREV-SVGADGPVVLASVFKVPLLVAFHRQAA -SGRLDPSEQVVLRAEDRTAPTGVSGMLDDVRMSLRDLTFLMITVSDNAAADLVLDRV-GR -DAVNATSAALDLPNTVVEDSGRELHEVLDPLRTSRSTPREMTRLLSLIWRDEAAPAEGCA -AMRRLFGLQVW-PHRLSSGFPDDVLVSGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRS -LLAVLPQADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. A23 TaxID=2606593 RepID=UPI001270F313 --------LSDIFEAAGVRGFLHARSLGSPVSV-DVDADSPVVLASVVKVALAYEFARQVA -AGQLDPTDRVHATAADRLGGSGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV -ANVRSLLAELGLTRTSVIGAPRDLLRALDPLRTSASTPREMTALLSALWSD----PGPGA -QVLAWMSAQVS-WHRLTAGFPPEVTVAAKTGTMP-GIRNEIGVVTYPDGTAYAVAVFTVG -GAETRPDIDRAIGDAARAAVDQ- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI00064D95C1 --qHVDAALAPLLAATPARVSLSLRDLDGGTVL-AHHADRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPACGGRAGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H0U0S9_SELRU ---DLQANTARIIGTSKNQMSVYFLRPDREIEP-FLYNQRQMSPASIIKLFVMAKTMQDVH -DGRLSLEDKVTIRKNDVVGGAGVTTWYDGQQRTIRQLLTVMITDSDNTATNILIDKL-GM -KNINQYIAQSGYSDTVLAHKMMLSN----GGRKNLSSVRDLGHLLTKLYYHQLVGPEEDE -FMLSVLKQQHD-KECLGSALN-GYTIAHKTGEVT-GVYTDGGIFIGKDED-FILVIINNG -TEGR------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK038 TaxID=2512156 RepID=A0A4V2U1Y9_9ACTN ----TLRRIAAAFAEAGVSGRLHAVDIDSAAEI-DAGADHPVVTASVHKLCLLVALHQHAA -AGLLDLTEQVECPPGERTPGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DAVNEATARLGLTRTRAVHTFRSLFAALDPARGNRSTPRDMTRLLTAVWRDEAACTPEHG -AAIRRLLGLQVWPHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVVEYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ306 TaxID=2035248 RepID=A0A2M9B264_9ACTN -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pedobacter insulae TaxID=414048 RepID=A0A1I2UBN6_9SPHI --hKLNKMLTEMVKGFNGDVGIYIKNLKTGKVA-SLNADTIFPTASMIKVPITCGIFNKIE -KGELAYQTELVYKDSLLYAGEDLLGSFKNNEIVLSKVLMLMITTSDNTASLWSQSLAGTG -TVINELMENYGFQHTRVNSRTPGRADNQRKYGWGQTTPREMATLLTLIRDGKMINEAASE -RIYRNLIRIYY-DHEALSEIPPYVQVASKSGAVN-AARSEVALVNAPHGD-YVFCITTKN -QKDTKNEGTTLIRKLSKTLWNYf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149RMK5_9PROT ----LAQIMAKTVSNQPGHFAVYAARSGQAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT -KGTLHPEDTIVVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVKAQGLNGIVFGRMIEDFDAN-NQGIRNQVSARGLGNFLQKLDSGKIVGKAQSQ -SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG -LP-DEQAGIRVLNTLSHQAYEYf ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A174D714_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EIGADEKFETASTIKAFILAALYLQVS -RGKASLEEEITYEESQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINGCIRELGFADTVLHNPLH-FD---RYDDLGTTTPRDYAALFAQVAKGTLVSKEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma rigui TaxID=564064 RepID=UPI0009AF3FBF ---KLEKELRAALTGFRGNVGIYVRNLRTGRTV-AINADTLFPTASTVKIPIQCGLFDKIH -RGELLYDQPLVYKDSLHYDDGIVGSLKDGATISLSKVVMLMETVSDNTGSLWCQALAGGG -ATINQWLETNGFHQTRVNSRTPGRAANQKQYGWGQTTPRELANLLTYIRQGRAVSADASD -EMYRNLGRQFW-DNDGLSQLPPDIKTASKNGAVNQ-ARSEVVLVHAPHGE-YVYCVMTKN -QIDETNEGYTLLRNVSAIIWHHf ->[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-893 TaxID=2682778 RepID=UPI0013ED9822 ---DIEASLSQLIEDSGASASFAYRYLSSGWDF-SVHGKESHTAASMISLAVLTQLFDRID -AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM -DAVNSEVARQGLEGTSLERHMMDTEAQ-KEGRENRMAADDAAAILNAIAQGAFYNEELSD -FAYDLLSQQKS-DSAVKGALPEGATYAFKSGSLEN-VYNEGGVVFG--EHPYVFVAFVEG -VD--EEEATALVKDAAALV---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=UPI0011A52442 -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3H2U9_9PSEU ---TVETQIAQVFADAGAQGFLYAREIGGHAEV-SVGGDDQVVLASVLKIPVGVAYAREVV -AGRLDETARTKVGARYRVGGIGTAGCADDVEMSWRDLALLMLTISDNAATDVVFHRV-GQ -EAVDQVLADLGLGRTRILGCCEDLGKVLDPARTTSSTPREIARLLEAIWTDEAAEPAACE -RVRSIMAKQVW-PHRLSSGFGDEVQVAAKTGTLP-AVRNEAGVVSFPDGRRFAVAVFTRA -ESFRLPAVDASIGKAARLAVDH- ->[subseq from] Uncharacterized protein n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A2M7RS34_9BACT --eRLKNTIDKALKEAQGTYGIVIRNLNTKEEY-YLNEHREFDTASLYKLWVMATAFTQIQ -SGQLKLSQNIQVLNNKFNIGSESTELTEGTIVSVKEALNKMITISDNYAALLLSEKV-RL -SNVSDFLKKNGLIESRLGEP--------P-----KTTPYDIALFLEKLYKNELANEDNTQ -KMIELLSRQTL-NNKLPKYLPSNLSIAHKTGELGY-FTHDAGIVFTNKD-EYLIVVLSES -DNPS--GAEERIAEISKAVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Emticicia sp. TH156 TaxID=2067454 RepID=A0A2N4X8U5_9BACT --kKLKAQLQEILNGFNGDAGIYVQNLKTNKYV-AINADTVFPTASMVKIPIMIGTFDKIR -QGSLQYEQELIYRDSLHYDDGIVGSLRDSAKIPLSHVMMLMCTISDNTGSLWLQALAGGG -NRINAILDSLGFVVTRVNSRTPGREAYRSQYGWGQTSPREMAKLLTLLRRGEIISPAYSD -RMYRNLGRQFW-DSHGLSQIPENVKVATKNGAVNR-SRSETVLVHAPGGE-YVYSIITKN -QKDETNEGFELLRKVSALLWHYy ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CLI2509 TaxID=1984801 RepID=A0A249LZR1_9ACTN ---AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CEV 2-1 TaxID=2485153 RepID=A0A3N1TLC4_9ACTN ---TAEERIRAAFDEAGVEGFFLAREIDGDRTI-GVSADEPVVLASVFKIPVALAYAREAA -AGRLERTERLAVDARYRDGGIGTSGCADPIEMSLRDLVHLMLTMSDNAATDVVLARV-GL -DTVNGLLRELGLERTHLVGGCLELISVCVPELTTRSTARETAELLARIWRDEAGSAVACA -EVRAVMAQQIW-PHRLGSGFDDSYRLAAKTGTLP-GWRNEAGVIEHPGGGRWAVAVFTRS -DTPDNPRADRVIGQVARLAVDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=A0A543VZ16_9ACTN -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Caproiciproducens sp. NJN-50 TaxID=2507162 RepID=A0A410PZB4_9FIRM ---KLNQFCKREIGRSGARVSLLVHDLTEGRDLiSIEAGHRVVSASTIKTAIMLAAFRLVL -DGKLSLSQTVRVPEEEVLDDTLVFDAGM-RECSLEEMITWMIVNSDNTATNVLIDVV-GM -EAVNGFCASLGLKSTGLQRKMLDGAA-VRSGRNNYTSAADQLLIYSALFRESILTPGLCG -LAKSILLRQRDCTMALRYLCGESVSFAHKTGGLDF-LRHDAGIFDLPGQA-YYFGCFVTG -CMDENPVAERLIGTLSKAVYESf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A4P5V5E9_9CHLR ---DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD -DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMIILSDNTATNMIIDLT-GL -GSVNNLVTSLASRVTRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPIGRQ -AFWQTLLRQQD-RAMAPRQFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ ------------------------ ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=A0A1Q5EVF4_9ACTN -----ERTIRSLFDDAGVRLHVAELDRPSARVV--VDPDEQVPMGSVYKVALMAAFCRLAD -AGRVDPRRRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -EAVDAVCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPEGCS -FMRAAMLTQPW-THRLASGFPDEVTVYGKTGTFGS-MRHEAGVVELGDGSVYTAVVFTQA -ARADLPRADAVIGAVARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Jonquetella sp. BV3C21 TaxID=1111126 RepID=UPI0003ADDDAE ---RVASQIANRVYESGVQASVVLADPATGEQF-DLRGLQRLKSASLIKLPILWDLFARAE -EGSLNLSETIVVPSEKRVDGGLLHKFSASPTLRLEDLAVLAGTVSDNTAANLLMDRL-GL -DGINDRIRSLGMKSTSLERRMLDSGAA-KAGKDNWTTTCDVALFLSALTSTAGLSEAGKR -RIIDILSAQKL-QSKLAGAIPCDKVLAHKTGELP-GHEHDAGIFFPFGPRPAVLVVLTTG -LT-DRLDGVRFCSALGRLVYDEw ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonas sp. SG8_28 TaxID=1703357 RepID=A0A0S8AP27_9BACT ---TLAAQLRPLAESFRGKVGIYVRHLGSGAAV-ALDADSLFPTASMIKVPILIGVFDRLE -RGELGFLDTLVYTDSLLYPGEDILGSYRDSAVPLAQVLMLMITTSDNTAALWSQHLAGTG -TRINAWLGDHGFPHTRVNSRTPGRERDRQAYGWGQTTPREMAELLVTIREGLAVSPAASE -AMYRFLTRIYWN-GEALSQIPPWVQAASKQGAVDR-SRSEVVLVNAPSGD-YVFCVITKE -QEDEENEGYVLLRKVSALLWRYf ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacter ethanolicus CCSD1 TaxID=589861 RepID=C7IRL1_THEET --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR -DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=4 Tax=Thermoanaerobacter TaxID=1754 RepID=E8UVF3_THEBF --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR -DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=unclassified Thermoanaerobacter TaxID=2636821 RepID=B0K5X9_THEPX --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRIV-GR -DNYIKFMEKLGAYVIPYS--------------NNVTSPRDMSMYMKNLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDAAIVFHPTR-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=A0A3A9UT42_RHOOP --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFA -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSELDMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGSAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rubrobacter radiotolerans TaxID=42256 RepID=A0A023X6K6_9ACTN ---DLEARIRAIAEIYPGEFGVVVRDPRTGETA-GLNPDQTFTAASLAKLPVLLALYGEAA -DGRLDLEEKIVMEAQDVQLGAGVLQNYPVGHMTLRECAELLIKESDNTAWVMLERRL-GR -ERIEHEIESLKLSGTDYAA--------------LTTTPEDVLRMLEAIADPDHTTPELSA -EMLAHMTDTAY-EGRIPEPLPKDVRVAHKVGTLND-TRSDAAIVFRQDRVDYMIVVIASG -GT--ERSATDAIRRISLSAYE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. DfronAA-171 TaxID=1839777 RepID=A0A1C4KKS6_9ACTN ---AVADRIAAAFADAGVDGVVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRRTRAVESFAATQKALDPAHGNRSTPRELTRLLAALWRDEFLPAAHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A3M1JUJ7_9BACT ----LKTRLERMAADFRGEVGIYVHHPARGLTL-SIHGDDLFPTASMVKIPIMIGIYDRIE -KGELSLDSTLIFHRDSIHYGDAVARFAEGEDITLGKLLAHSITFSDNYASIWLQQLAGTG -TAINAWLADHGWEQTRVNSRTPGRQSNWEEYGWGQSTPEEMARFLLALRRGNVVSPRASE -DMYRYLCRSYW-DGEALSQIPPWVQAASKQGAVDE-ARSEVVLVNAPHGD-YVFCVMTNH -QTDQDNEGFVLIRRVSRLLWQTf ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. MD40 TaxID=2029590 RepID=A0A2A2SB68_9SPHI ---KLTVQLQNLLKDFHGRAGVYVHNLKTGKTA-AINSDTLFPTASMIKVSILNGVMDKIE -KGDLHYNQKLVYRDSLLYAGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQKLV-GG -EYINNWLATNGFKVMRVNSRVAGREDMRKIYGWGVTTPYEMCRLFTLIRDGKAVSPAASE -RMYRTLNRIYW-DENALSQIPPYVQAISKQGAVD-ASRSETVLVNAPHGD-YVFSIITKN -NLTPQNEADILIKKVSALLWHYf ->[subseq from] Serine hydrolase (Fragment) n=2 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9CKX7_9CHLR ---NLESTLDNIINQFEGVAGLSIRCLNNNKTI-SINGDDIFPTASSIKIHILTQLFTLED -KGTIDLAKRVRFTQDMYGAGSGVIHFLENEPFTILDIAILMMLVSDNTATNMCIDLA-GM -QETNNLIKDLGLSKTKLGRKMMDPD-AINRGEENISTPNELTKMMELLYQKKP-SPKVAE -NVLNIMSKPKS--AYLNKAIGPHTKVANKPGGMDK-VRCDVGIVY--------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter psychrophilus TaxID=651661 RepID=A0A1T5CAR3_9BACT ---KLVKKLEAAMAGFKGDAGIYVRNLKTNRVA-EVNADSVFPTASMVKVPILCGILDKIN -RGEVAFNQELIYRDSLKYDNGIVGSFRDSTRIALPKIVHLMISQSDNTGSLWLQAMAGGG -ATINQWLDNNGFANIRVNSRTPGRKENQAKYGWGQTTPREMAELVAMIRNGKAISPAVSE -RMYRYLGMQFWDGESI-SQVPPTIKIAAKSGAVNQ-AKSEVLVIHAPHGD-YVFCVATKN -QEQKNNEGYVLIRKLSAIIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB03238 TaxID=1907777 RepID=A0A1X1NF60_9ACTN -------------AQAGVEGYVHARDLDTGEEF-GHGADTPVVLASVFKIPIALEYARQAA -AGELDPARRHTVTPAYRAGGSGTDGCAYDVEMSARDLAFMMTTISDNAATDLLLDVV-GP -DRVRRTLDDLGFPGFGFSSSAA-LDDACAPGSSPSSTPREVTALLAAIWRDEAGPASACA -EVRDIMGQQVW-QHRLVSGFPAGMRLAGKTGTDF-AVRNEAGVIEYPDGKRYAVGVFLRT -STAAQPLADRAIGRAARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter ginsenosidivorax TaxID=862126 RepID=A0A5B8VWA3_9SPHI --kKLTAQLQDAVKGFHGQAGIYIQNLKTGKTV-AINADTLFPTASMIKVSIQCGLMDKIE -KGELRYNQKLVYRDSLLYAGEDILGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -DYINNWLQQNGFKVMRVNSRVAGREAIRKIYGWGVSTPYEMCRLFTMIRKGEAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSVITNH -NTDQSNEAGLLIKKISALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Rhodohalobacter halophilus TaxID=1812810 RepID=UPI00083F9A1F ------EAIRTLAESFNGDVGIFVKDLETGKEF-EFRADDVFPTASMIKIPIMVGVFDKIE -KGELKYQMKLEYGPESEYEYSGISNLESGTEVTLSLLVHLMMSVSNNTGSLWNQYLAGTG -TEINSLMEELGFEHTRVNSRTDGRSEAFQMYGWGQTTPREIATLVEKIYKGEIINKHASE -QMFRVMSRNHW-DGEALSQIDPVINVASKNGAVS-ASRSEVLLVNGPSGD-YLFSVITKN -QEDRDNEAWVMIRELSSILYRHf ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacter italicus (strain DSM 9252 / Ab9) TaxID=580331 RepID=D3T4F6_THEIA --qELKNNIQALISQYPGKYGVYFIDLNTGQTL-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMEKLGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDTAIVFHPAR-PYILTVLAND -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacter mathranii subsp. mathranii (strain DSM 11426 / CIP 108742 / A3) TaxID=583358 RepID=D7ARJ7_THEM3 --qELKNNIQALISQYPGKYGVYFIDLNTGQTL-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMEKLGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDGIEVAHKIGNLSN-VVNDTAIVFHPAR-PYILTVLAND -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CFMR 7 TaxID=1649184 RepID=A0A0M4DHD5_9ACTN -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETALLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. RB56 TaxID=2585199 RepID=UPI00129735D8 ------------FEQAGVRGVLHARCLGTGAEI-DLGADDPVVLASVVKVPLVLEFGRQVA -AGQLDPADRVRAVAATRLGGTGLAGCADDVELSLRDAAYLALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLHRTRIVGAPRDLVRALDPLRTNASTPREMTGLLAAISRDEAGPPEVCR -WLRGLMSQQVN-WYRLAAAFPPEVAVWGKTGTLP-GLRHEIGVVEYPDGGRYAVAVFTRA -GTQRLPQVDRAIGVAAREAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WZ.A104 TaxID=2023771 RepID=A0A2A4KTK1_9ACTN ----TLQQIHSAFSEACATGWLHAVDIDSGAEV-NANADGAVVTASVHKLCLLLALHQQAE -QGLLDLTEQVECATDGRAAGPTGLAVMLDPVISLRDAAYLMMAVSDNAAAEVILERV-GL -DAVNAATTRLGLTHTRAVHTFAHTLAALDPARTNRSTPRDMTRLLCALWRDEACSPEGCA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-VRNEVGVIEYPDGGRYAIAVFTRA -VNATLPSVDAVIGTTARLAVD-- ->[subseq from] Serine hydrolase n=2 Tax=Cyanobacteria TaxID=1117 RepID=A0A1Z9LHM9_9CYAN ----LSKRWNQLAAQQDLQASAFMLILDDGRYA-AMAADRAMPAASSIKTPILLAVLEQLD -XGXLQWNEPLTLTKELVGGGAGWMASRPIGSFPTYEVATEMIRVSDNSATNLMIARAGGQ -QAINERFQELDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLAPRSRD -LFREVMSTSVT-NTLLPRGLLKGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTELIRQLAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI00130EC88A ---TLEKRIEAELMSYDGKMGIYLDDF-HGNVI-SIDGDEAFETASAIKTYILVCLFDQVE -KGNKSFEDVIEYKQEHVVDGSGVLPALEPGALRVKDAATFMIIVSDNIATNMIIDYL-GL -DTINQCIRDLGCRDTVLHNPIH-FE---KYDKLGTSTPRDYASIFTRLAKGELISRSADE -KMVEIFKKQHY-NTMITRDFPAVISVASKSGSMD-ACRNDGGIVFTPYG-PYAIVMFHKE -FSDASHPATMFGARVSRMILDQf ->[subseq from] hypothetical protein n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0002DD1BDF -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETALLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium RIFCSPHIGHO2_02_FULL_38_14 TaxID=1802620 RepID=A0A1F4V8G1_9BACT ----LSHLLDKELAKLNGSVGLNVKFLSSNEIY-TYNGKTQFWSASVIKIPIALTFYEQIK -EKNINDTEKVKITEDNYVLGSGIAKLLDKNNYTFKDLITLMLVVSDNTATNQIVDFI-GW -ESVEKYMKEIGLENTTFKHKMMI--K--AGRGPNLTTPEEMTTLLERMYKNEL---PGSE -IVLKIMQEQLD-RTRIPQLIPNEIPISHKFGTLPE-ALHEVGIIYSKN--PFIFCFFSDD -QK-DKKLTNEVLSVCAKHCFD-- ->[subseq from] Uncharacterized protein n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2ENL5_9ACTN --------------GVRVSVGLADLSRPNGRST-ILGSTASYNPASVIKLSLLATLMRQVD -RGLVSLDAPVTVSPYMVVGGSGTIQDEPMPFTTVRELARRMVVVSDNTATNVLLYYV-GI -PTVQALLDDLGLRTMKFNRQMF--PGALISAPTNVLDAADTLALLKATYSGRLLSRKSTE -QIVDWMRHQEV-DTKFGAVLN-GRPIAHKTGETGN-VTHDVGYFLVPGHE-TAVVVLTEV -TTEAQRIGNPIVQNIGLAVYDH- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFOXYB1_FULL_47_11 TaxID=1798401 RepID=A0A1F6BEJ3_9BACT ----LKKKVQETIDNTWNNYSVYVVDFNSNFTM-GINENEIFTAASVNKLPIMAAVYYKAQ -KGEVNFDQIVTLQPEDIQDTGSIRYDAPGTTYSVKTLMRLMMQKSDNTAAFLLGNYIVEL -PAIQSIISEWGLTQTDMVN--------------NKASNHDMYILLNKIYGNNITNAALTA -EMLGFMRDSDF-EDRLPGELPKEATVYHKIGTGDGGIIHDVGIVVNGKT-AYYVGIMTAD -IP-DPENAAKLEAKVSKIIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Caldanaerobius fijiensis DSM 17918 TaxID=1121256 RepID=A0A1M5CIK2_9THEO --sALKAKLQRYINTRPGQISVYVHDLTTGQTL-SIGGDRVYAAASTIKLPLVLYLYEQAA -AGKVDLNTKLTYTPQYYMQGTGILQGQPFGGYTIRELSRLAIEYSDNVAWQMLLDYA-GQ -DNLTAFEKSLGAKATGLVNGLS------------VTTPKDMDIYLSELLTFRDENYDLGN -EVLYYMEHSIF-SEGIPQELPSGVVVAHKMGALDD-KFHDVGIVFG--NRPYIITIFTEN -GWED--ASLQTLADISRIVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=uncultured bacterium TaxID=77133 RepID=K2DJJ4_9BACT ---DLKNEIDKITKDKKGFYSIYYKDLKTGSFF-GIDEHQIETGASVNKLPIIAALYYLDK -QEKISLDDKITILEKDVQNTGSIRYQKMPQTYSLRNLAKLALKQSDNTASYVISLKI-GE -ENVQKLVDSWGMKQTNMKN--------------NKTTAFDMSLLFEKIYTNQITDPARTK -ELLEFMTETDF-EDRLTKGLPSNVKIYHKTGDEE-GFVHDVGIIETEKGT-YYLGVMTSD -IGENEEETKNTIAKISRKILE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A1V4AB41_9ACTN ------RAIRSMFADAGVRGWLHVADVHRTARV-TVDPDEPVPVGSVYKLPLMAAFCRLAD -SGAIDPLLRVTLGPDDRMPPTGLSILRDPVTVSLRDLVVLMMSVSDNTAADAVLRRV-GT -AAVDELCREVGMPDTRILGGAATTFEVYDPLSKASTTPSDMARLLRAIWTDGAASAESCA -FMRETMGRQAW-SHRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGGTYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SAT82 TaxID=2024887 RepID=A0A2E2G888_9SYNE ---------REIAATQXLMXSAYLLILDDGRYA-QLNANRPMPAASSIKTPVLLASLERID -AQDLSWNEPLELTEDLVGGGAGWMASRPVGSFPTYEVATEMIRISDNSATNLLIERAGGQ -QVVNERFRSLGLPATVINNWLPDLDGT------NTTSAHDLSRSIALVDSGDLLSPRSRD -LFRQVMETSVT-NTLLPTGLMQGYRVLNKTGDIGI-AYADAGLIELPXGRRAVAGFLVKG -PFXD-PRSTNLIRAMAKAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Jiangella asiatica TaxID=2530372 RepID=A0A4R5CQZ8_9ACTN ---------KGAFADAGVTGHLHAVDIDSGAEA-GLDADAPVVTASVFKVPVLVELCRQAA -AGERSLTDRVRVPAAPRTLGPTGLSVMLDDILSLRDLAYLMMSVSDNHATDVLVRLL-GI -DRINAGLAALDRHDTVVMGDCDYLFSALTAEQTNRSTARDTTALLRRVWTDDGLAPDAAA -EVRRIMALQVW-PHRLTSGFPDDVKIAAKTGTLSH-VRNEAGVVEYPDGSRFAVAVFLRL -PGRENPAADAVIGRAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000365ECD6 -------TVRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT -DAVDRMCAGLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA -FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. CH32 TaxID=2530383 RepID=A0A4R4ZJS6_9ACTN --------------AHGVRVSVGLADLSNGQSA-ILGSVASYNPASVIKLSLLATLMRQVD -RGLISLDAPVTVSPYMVVGGSGTIQEHMPFNTTVRELARRMVVVSDNTATNVLLYYV-GI -PTVQALLDDLGLKTMKFNRQMFP--GDLITAPTNAIDAADTLSLLKATYSGRLLSRTSTD -QIADWMLHQEV-DTKFGAVLA-GKPIAHKTGETGN-VTHDVGYFLVPGHE-TAVVVLTEV -TTEAQRIGNPIVQNIGLAVYDH- ->[subseq from] Uncharacterized protein n=1 Tax=Leucobacter komagatae TaxID=55969 RepID=A0A0D0IQD6_9MICO -----------VAEDAGVFAFAHARDIDTGAEV-GFDSDAPTVTASVFKVPVLVEYVRQVS -AGELDPAQRVRFLPADATLGPTGLSVFSDEAWSLRDVATSMITVSDNAATDIVTGMV-TV -DRVNQTMRELGLPGTQLTGDCARIFEAATPEKTNRTTPREATSLLQQIWTDAAASPEACA -EARRILGLQVW-PHRLSSGFPDDVKISGKTGTLGM-VRNEIGVVEFPDGTRHAIAVFLRG -KTSRNPAADRAIGDIARLLSD-- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. PAMC 26640 TaxID=1300914 RepID=A0A142HZM3_9SPHI --kKLTAQINTAIKGFNGKVGIYVQNLKTRKTV-GINQDTLFPTASMIKVSILSGVMDKIE -KGELKYNQKLGYRDSLLYAGEDLLGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-TG -EHINNWLDRNGFKNMRVNSRTPGRQAMQKIYGWGVTTPYEMCRLFTLIRNGQVVSPAASE -RMSRMLNRIYW-DNTALSEIPPFVQALSKQGAVDD-SRSETLLVNAPHGD-YVFSVITKN -NKTPENEADLLIKKVSALLWHYy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=UPI00084CBD44 -----RDRIRAAFAAAGVTGWLHAVDIDSAAQI-EVGADQPVVTASVHKLCLLVALHQHAE -AGRLALTDQVESPAGGRTPGPTGLSAMLDPAVSLRDAAYLMMAVSDNTAAELLLARV-GL -DAVNETTERLGLTRTHAVQTFGEFITALDPARTNRSTPRDMTRLLGAIWRDEACTPEHSA -AVRRLLGLQVW-PHRLASGFPDEVHVAGKTGSAPT-LRNEVGVIEYPDHGRYAVAIFTRA -ASAALPAADAVIGTTARIAID-- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacter uzonensis DSM 18761 TaxID=1123369 RepID=A0A1M4W3N5_9THEO --qELKNNIQALISEYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMRMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus opacus TaxID=37919 RepID=UPI0002A247FF --------------------------IDDGGDI-AVGADDLVVLASVYKLPLLVALCRAFA -SGELSPTATVRINPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESVERALSELDMTSTRIIGGTADAHRAYDPSYASATTPREMTSLLDAIWTGSAVPGPQGE -FVRHVMSAQIW-QHRIRSGFPSEVDVAGKTGTIG-AIRNEVAVVTFPGETPVAVAVFTRA -ARTDLPVVDAAIGHAARIAVT-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Faecalibacterium TaxID=2646395 RepID=A0A1Y3WNY6_9FIRM ---TLEKRIAAELYSYRGQMSVYLDDL-RGHTV-EIGADEPFETASTIKAYILAALYLQAS -RGQASLEDRITYQPQHFVDGSGMLRAGVGAALKVKDAATLMIICSDNIATNMIIDYL-GL -DQINRCIRELGFAHTVLHNTLHF-DR---YSQLGTTTPRDYGSLFAQVARGSLVSPQASR -EMLTIFRAQHY-NTMLTADFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN -FEYNAHPAMVYGARVSRMVL--- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. F-1 TaxID=463642 RepID=A0A1K2FPM5_9ACTN ----IEETIAEVFAAGGCRGSLCALEVDGPGRV-SVAGGEPAVAASTFKIAVGLEFFCQAA -QGELDPAERVVVSPAGATPGQGLCITEDPVEISLRDVARLMLTISDNTAADVLIRRV-GI -ERIRARLTGLGLTGFHLPGTIHELDTGMRPGRISSATADDLAALLRAVWRDEAGPAQACA -QLRRTMGQQRL-TRKIAAGFGPEVLVASKSGTVPGGVSNDVGVVAFPDGRRYAVAVLTRS -LTPGAPTREDVLGTAARVALDH- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Hydrogenedentes bacterium CG07_land_8_20_14_0_80_42_17 TaxID=1974588 RepID=A0A2M6Z723_9BACT -----NLKLSELISKCPGTPSIKILFLNSGYEM-EFRSGKVVRAASVIKLPICVAVMSLCR -KGKGSLPEPISLVEEDRTSGSGILRHRFNRDYTVEELIKLMILESDNTATNALIRRF-GL -EEIQNEFEKAGLIKTKLKHRILEASED------NPISSSEIVDLLSAIADESSIHPDDRR -WIFDLLKQTSP-GARLGRYLPDEAKIAHKTGTLRR-EVHDAGIIETDSNK-IIVSALIEK -AK-SRKEAERWLGRLGRLICE-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. S2-17 TaxID=1990687 RepID=A0A2S2BV89_9NOCA --------------------------------V-TVDGDDLVVTASVYKLPLLVALCRAFD -AGTLSPTSTVRVNPADCTPPTGVSMFRDPVVMSWRDLALSMMTVSDNAAADLILGGV-GL -DAVDRVLTDLCLTRTRIVGGTADAHRAYDPSYASATTPREMTALLDAIWTDRAVSPVQGE -FIRQVMAAQVW-QHRIRSGFPADVTVAGKTGTIG-AIRNEAAVVTFPGEIPVAVAVFTRA -ARADLPMVDQAIGRAAQIAVT-- ->[subseq from] Beta-lactamase n=2 Tax=cellular organisms TaxID=131567 RepID=A0A094YN85_9PROT ----LAQSISKTVKAQPGHFAVYAALSGYSPAV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPQDTVTVHNRSLVGTGTFAYAQAGKPVPVSELLRVMIQYSSNLATNLMVEKL-GV -MPIRSVVKAQGLDGIVFGRMIEDFDAN-DKGIRNQVSARGLGAFLQKLDNGQIVGKAQSQ -SMVQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVRNDAAIVTLPNGRHYILVVLTSG -LP-DEQAGIKVLNTLSSQTYAYf ->[subseq from] Serine hydrolase n=1 Tax=candidate division WOR-3 bacterium JGI_Cruoil_03_44_89 TaxID=1973748 RepID=A0A235BVI4_9BACT ---VLQRQIEASVENFQGDVGIYVRHLSKNITA-GINEDDLFPTASMIKVPILIKIFDKIE -KGELTIDSTVIYYKDSINYGDDAISRFKDGEISIGKLMAHMITFSDNHAGIWLQELAGSG -TEINEWLNQEGFRSTRVNSRTTGREDDYEQYGWGQTTPREMAELLVMIREGRAVSRRASD -DIYRHLTRIYW-DGNALSQIPPTIQVASKQGALDQ-SRSEVVLVNAPHGD-YVFCIITRD -QKDTSNEGSVLIRTVSNLLWNYf ->[subseq from] serine hydrolase n=1 Tax=Nocardioides jensenii TaxID=1843 RepID=UPI0012FC79B0 ------KDILKEAAAVGVRVWLQAQSVRSVTQV-GVGPDIPVVLASLLKVPVALELARRAA -SGEFDLDRQVTLSPADLTPPSGLGTLRGPVTLPVRDLAVLMLSLSDNAATDFLLSMV-GR -DAVERLLGELGLSRTAVPQDCAEIIRALDPDRTCRSTARETVSLLRAIWQNEAGPSAACA -NVREWLSHQAW-DNRMASGFEDDVEIASKTGTLP-GLRNEAGVVTYPDGGAYAVAVFTRD -EDSRNSSRDHFIGRAARLAVE-- ->[subseq from] Serine hydrolase n=2 Tax=Luteimonas aestuarii TaxID=453837 RepID=A0A4R5TRT0_9GAMM ------------------SVGLADVSRSDGAQR-IIGSTDSYNPASTIKLALLATVMRQAD -RGLLNLDAPIGISPYMVVGGAGDLQRQAMPFTTVRDVARRMVVLSDNTATNVLLYYV-GL -PTVQALLDDLGLQTMRFNRQMFPGEK--IGEPANAIDTADTLSLLHAIYIGDLLNEQSRR -QVLDWMLAQEV-DTKF-GALPDTSRIAHKTGETGT-VTHDVGYFLVPGHE-TIVAVLAEV -TTETMRIGNPVVQDIANAVLD-- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC333 TaxID=2070368 RepID=A0A2W2EL52_9ACTN -----------VFADAGVRGFLHAREVDGDAET-GLDPDEPVVLASVFKIAVALEYARQAA -AGEIGRTERLTVTSADKDGGIGTSGCQDDVSLTLRDLAHFMITMSDNAATDVLLRRV-GL -DRVNGTLAALGLRRTRLIGGCAELFDAVRDPARTTATSREITTLLGLIWRDEAGPPEACA -EVRRLMGEQIW-PHRLSAGFPDEVKVSGKTGSLW-GVRNESGVVEYPDGRRYAVAVFVRS -EVERLPHADAVIGRAARLAVEQ- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193C0Q4_AMYOR ------AEIEAVFANAGARGFVHAREVGGGPEV-GVSADDPVVLASVFKIPVAVAFAREVA -AGRLDETERTRVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLIYHRL-GQ -DKIDQVLADLGLVRTRLIGCCEDLFAVVDPERTTSSTPREITTLLDAIWTDRAGDPAACE -RVRTIMAQQIW-PHRISSGFPGEVAIAAKTGTLPS-VRNEAGVVTHVDGRRYAVAVFTRA -ESDRLPAVDSAIGEAARLAVEH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces griseus TaxID=1911 RepID=UPI0008407702 ---------RGMFDDAGVRGWLHVADLHRSAQV-TIDPGDQLPMSSVYKVPLMAAFCRLAD -AGRIDPGRRLTLGPDERVPPTGLSVLRDPVTLSLRDMVVLMMTISDNTSAHAVLRAV-GP -EAVDATCRDLGLPDTHIHGGVVSTFSVYDPASKASTTPADMARLLRAIWTDRAASEDRCA -FMRGVMRRQAW-SHRLGSGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSTYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter uzonensis TaxID=447593 RepID=UPI0009331BF4 --qELKNNIQALISEYPGKYGVYFIDLNTGQTF-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMESLGANVIPYN--------------SNVTSPRDMRMYMENLLNYVKAHPDTAG -ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPTK-PYILTVLANN -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Spirosoma pollinicola TaxID=2057025 RepID=A0A2K8YV55_9BACT ---SLERQLRSALSGFRGDAGVYVYNLRTGKTV-AINADTLFPTASTIKIPIQCGLFDKLH -KGELTYTEPLVYKDSLHYDDGIVGSLKDGTKIPLSEVVMLMETVSDNTGSLWCQALAGGG -TAINNWLETNGFHQTRVNSRTPGREASRTQYGWGQTTPREMANLLTYIRQGRAVSPDASD -EMYRNLGRQYW-DNDGLSQIPSEIKTACKNGAVNQ-SRSEVVFVHAPHGE-YVYCIMTKN -QKERTNEGFELLRNVSAILWHHf ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter gossypii TaxID=551996 RepID=A0A5C1IJG0_9SPHI --sKLTAKLNEAVKDFQGQVGIYVHNLKNGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELRYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -EYINNWLNQNDFKVMRVNSRVAGREAIRKVYGWGVSTPREMCRLFAMIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NKTPDNEAGLLIKKVSALLWHYf ->[subseq from] Possible beta-lactamase family protein n=1 Tax=Synechococcus sp. (strain CC9605) TaxID=110662 RepID=Q3AI91_SYNSC ---------ELAAQQSNLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -EAINARFQELDLPSTMVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRQLAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Eggerthellaceae bacterium zg-886 TaxID=2682776 RepID=UPI00140792DE ---DIEASLSQLIEDSGASASFAYRYLSSGWDF-SVHGKESHTAASMISLAVLTQLFDRID -AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM -DAVNSEVARQGLEGTSLERHMMDTEAQ-KEGRENRMAADDAAAILNAIAQGAFYNEELSD -FAYDLLSQQKS-DSAVKGVLPEGATYAFKSGSLEN-VYNEGGVVFG--EHPYVFVAFVEG -VD--EEEATALVKDAAALV---- ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=A0A358UXT9_9BACT -----NLKLSELISKCPGTPSIKILFLNSGYEM-EFRSGKVVRAASVIKLPICVAVMSLCR -KGKGSLPEPISLVEEDRTSGSGILRHRFNRDYTVEELIKLMILESDNTATNALIRRF-GL -EEIQNEFEKAGLIKTKLKHRILEASED------NPISSSEIVDLLSAIADESSIHPDDRR -WIFDLLKQTSP-GARLGRYLPDEAKIAHKTGTLRR-EVHDAGIIETDSNK-IIVSALIEK -AK-SRKEAERWLGRLGRLICE-- ->[subseq from] Serine hydrolase n=1 Tax=Acidaminococcus sp. AM33-14BH TaxID=2292909 RepID=A0A3A5RHZ6_9FIRM --dALQKDVEMYLAKRPGKTAVSCWLLTEKQGF-SIGGKNELPSASLIKLLVLVELCEEVR -RGRANLKEAISILGSAITGGDGIIKEKIGHTFTLEELATLMIIVSDNEAANQLIDRL-GM -KAINERAKKLGLAQTHLGRLMMADAS-GEKERDNWTSADDTVHLLRVICETAKTGSPLGR -WMISLLARQQQ-EGGLRRNLPDFVQVAHKCGNLA-GVEHDAGIFFG--KRPYLLAVLTTE -QPASY-VGRETIG---------- ->[subseq from] Serine hydrolase n=1 Tax=Balneolaceae bacterium TaxID=2053516 RepID=A0A6C1PAQ3_9BACT --rQLQHSIEGLLARFNGDAGVYIRHLPSGREI-AVNADTVFPTASMVKVPILAALFDRIE -NGDLEYREKFYFDGQHNYGFRDVISNMTDSSVYLDMLIHLMMSTSNNTASLWNQHIAGGG -EGINVWLGENGFEHTRVNSRTPGRGEAQARYGWGQTTPREMARLLEMIYLGEAVNPHASE -KMYRIMTRNFW-DGEALSQIPPYINVASKNGAVSR-SRSEVLLVNAPSGD-YLLCIITKN -QNDSENEGWVLARTISRLAWQTf ->[subseq from] Serine hydrolase n=1 Tax=Kribbella pittospori TaxID=722689 RepID=A0A4R0KW46_9ACTN ----------AYAGELGAEIWLHARDLATGRTV-GVDAETPVVTASVLKVPVALELARQAV -AGEMDLAERITVPAEGLVASPYGLAMHRDPTISYNDLALLMMVISDNVATDLVIDRV-GK -DRVAALLAELGLPGTAVPQNCAEILAALDPAATDRTAPDEITSLLAGIWRDEAADPEACA -LVRGWMGKQVW-PHRLSSGFPDDITVSGKTGTLPL-VRNEVGVVEFPDGGRYAVGVFTRA -ADPNAPQFDGLIGWAAAQ----- ->[subseq from] Beta-lactamase n=1 Tax=Synechococcus sp. KORDI-52 TaxID=585425 RepID=A0A076HH07_9SYNE --------VELAEEQSDLDASAYMLILDDGRFA-AMQAEVPMPAASSIKTPILLAVLELLD -QGTLRWNEPLTLTEELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNTATNLMIARAGGM -DEINARFEALDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD -LFREVMGTSVT-NTLLPKGLMRGYRIYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTELIRRLAAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 4R-3d TaxID=2559605 RepID=A0A4Y8XXV1_9ACTN ---------------LDARVWLHARCVDCGRGT-GHGQDEPVVLASVVKVLLALEFWRQAA -AGQLDPAEVVVVRAADRLGGTGTAGFHDDARLSLRDLALLMMSVSDNTAADILFRRV-GL -DTVQALARQLGLDRAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGPAVACA -GVRDLMAQQVN-GARLGAAFDRFTTVVAKSGTLP-GVRNEIGVVTCPDGARYAVAVFTRA -TSTRRPDLDAAIGEAGRGAV--- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C13483 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter oryzae TaxID=468058 RepID=A0A316HIY5_9SPHI --hKLAVKLQDAVKGFRGHVGIYVQNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLVGGP --YINNWLEQNGFQVMRVNSRVPGREAIRKIYGWGVTTPREMCRLFTLIREGKAVSAAASE -RMYRNMGRIYW-DEDALSQIPPFVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NTTPNNEAGLLIKKVSALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Anaerotruncus TaxID=244127 RepID=UPI0013632499 ------EQILNELSQMEGKVGFYYHNLVTGETY-GYREKEPFLPASVIKFPLMAAILLLRS -RGEADFREEILIHQDQKVPGCGAVQHITGEVLDMETLGKLMITISDNTATNALLRHY-TV -PKIREAFLELGLIGTQFNRELWDLERE-ARGINNYFVPEEIGILLEKIYHKTLVNEESSI -WLDDIMRQQQI-NHKMGGHLIMDYPMAHKTGDEED-KAHDVGIVYAK--QPFVVCFASNE -VD--VPMYEDFIRRTTKALVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Chitinophaga polysaccharea TaxID=1293035 RepID=A0A561PTX3_9BACT ---RLTAILQPMLQSFHGVAGIYVHHLGKDRTV-AINADTVFPTASMIKMVIQVGIFNKLA -AGELQYHQNLLYRDSLLYKGEDILGSFRDSEIALDKVVMLMLTMSDNTASLWLQSLAGGG -AVINQWLAGQGFEHLRVNSRTKGREANREAYGWGQTSPREMARLMEMIYRGEVINKTASE -RMYRNLTRNYWDAQGI-LQVPPNVRTASKNGAVDE-SRSEVIMVNAPRGD-YVYCMITKN -NKNHDNEAWQLLRKVGFAIWQYy ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=A0A1C4U6Y3_9ACTN ----------VIFAAAGVTASLHAVDLDAAREV-GVRADEQVVIASIFKVLLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCVDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRIRGGPRELVEVFDPAHTTSSTAREITRLLTMIWRDEAGPAAACA -MVRTWMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DQSRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Dyadobacter luticola TaxID=1979387 RepID=A0A5R9KXY7_9BACT --kKLTNKLVQALTGFHGEVGVYVRNLKTGKVA-LVNADTLFPTASMVKVPILCGVFDKIN -KGELTFNQELIYRDSLKYDDGVVGSFRDSTKIALPKVVHLMISISDNTGSLWLQALAGGG -EAINSWLDTNGFSQTRVNSRTPGRKAFQARYGWGQTTPREMAELVTMIYNKKAIEPEASE -RMYRYLGMQFW-DGEAISQIPPYIKTAVKNGAVNQ-ARSEVLVVNAPHGD-YAFCITTKN -QQQKDNEGYALIRKVSAIIWNHf ->[subseq from] serine hydrolase n=1 Tax=Jiangella asiatica TaxID=2530372 RepID=UPI0013A5C64E -------------ADAGVTGHLHAVDIDSGAEA-GLDADAPVVTASVFKVPVLVELCRQAA -AGERSLTDRVRVPAAPRTLGPTGLSVMLDDILSLRDLAYLMMSVSDNHATDVLVRLL-GI -DRINAGLAALDRHDTVVMGDCDYLFSALTAEQTNRSTARDTTALLRRVWTDDGLAPDAAA -EVRRIMALQVW-PHRLTSGFPDDVKIAAKTGTLSH-VRNEAGVVEYPDGSRFAVAVFLRL -PGRENPAADAVIGRAARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Niastella yeongjuensis TaxID=354355 RepID=A0A1V9EX08_9BACT --hRLQQKIQETVKGLDGDIGVYVKNLRTGKMA-AFNADTIFPTASMVKVTILIGIEDKIE -KGELDYHQQLEYRDSLFYAGEDILGSFKNGEIGLHKVMMLSLTTSDNTASLWLQSLAGNG -TRINQILDSLGLVNTRVNSRTPGREASRQQYGWAQTTPREMGTLMEKIYNGEVISKKAGE -KMIRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPHG-PYIFSVETKN -LKDNSNEAWLLTRKLSALCWNY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. B27 TaxID=2485015 RepID=UPI000FD9CC6A ----------SLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLAVQMMSISDNTAAHAVLRAV-GT -DAVDRMCADLGLLRTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=UPI0011DE3273 -------------KSIEGDVSFYYKNLITNKTV-AYNEEKIMLAASVIKITVLVEAFKQIK -EGKIKKEELFITCEDDKVPSCGALNYMREGLVTLEDLYILMIILSDNYATNMLIDKL-GM -DNINNTIKEIGLKNTVLNRKMFDSKKATLG-LENYISASDVGYLLEKMYNKDLIDKKSSE -EMISILKNQRLNGKMFLQNLKPKIEIAHKTGEDTN-ITHDVGIVFAK--EPFIVCFCGNN -V--NVPEYERLIQDITYDLY--- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. MED-G133 TaxID=2518986 RepID=A0A520LPG6_9SYNE ----LSARWRAIAAQKDLEASAYMLLLDDGRFA-QMNADRPMPAASSIKTPILLTALQRID -AGDLHWNEPLLLTKELVGGGAGWMASRPLGSFPARVAATEMIRVSDNSATNLLIERVGGQ -QTINQLFQDLGLMATEVNNWLPDLDGT------NTTSAYDLSRSIALVDTGETLSLRSRD -LFREVMATSVT-NTLLPTGLMKGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRAMAAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus bengalensis TaxID=1435466 RepID=A0A494Z079_9BACI ------------TSKVP---GIFSINMNTPDRI-NINGGKMRKAASLAKLFILVEAFRQSQ -DGKLSLEKQIHIEKEHLAYGAGVITYLTGSRFTYRNLIELMIIVSDNTAANLMMDVV-DR -HNVNKLAKQIGCTKTVINRKFMDVTAQ-QVGKENYTSANDVIKLLQLISKNNILTDHSRT -QIMNILSDQQL-NHKLPSNIQHHITFYHKTGELP-GVEHDAGIVVNKQK-LVEVAVLSEG -W-VEAGTAQSYISEISKVLIQY- ->[subseq from] Serine hydrolase n=1 Tax=Jiangella sp. NEAU-YY265 TaxID=2293569 RepID=A0A418KHX7_9ACTN -----EGELRDAFAAAGVSGYLHAVDVSSGTEV-GLEPDAPVVTASVFKVPVLVELCRQFA -TGERAPTDRLRVPAGSRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -ECVNAAMAALGLPGTVLEEDCAGLFRVLDAGTTNRSTPRETTTLLRRVWTADGLPEQACA -EIRRIMGLQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGATFAVAVFLRL -PGAENPAADRVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Clostridium perfringens TaxID=1502 RepID=UPI000D95760B -------EVQKYLESRIGSYSFFFEDLKSGYTY-GYNENVKMISAGCMKLPIAIALIKEVE -EGKIDFLDKVKIESSDKVYGTGIIHEFGERDYTVFELMVAMLIQSDNTAANKIIDLV-CM -DKINETIKEFGMKNTELNRKTAD-ERNFKSDVENYTTAYDLTLAWKKLSEGSFLSKENSQ -MLIDILTRQQI-KNKLALYIPDNLKISSKTGDKK-GVENDTALIHTQKGN-FACTVMSSG -IPNS-VYGTVTLAKSGKMTWD-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW69 TaxID=368493 RepID=UPI000E0F1C55 ----LSQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMPAASSIKTPILLAVLELLD -QGTLQWNEPLTLTQELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGM -EQINARFQELDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD -LFREVMGTSVT-NTLLPTGLMRGYRVYNKTGDIGL-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTELIRQLSAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ZEA17I TaxID=2202516 RepID=A0A2V2PQX2_9ACTN ------RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA -FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Emergencia sp. 1XD21-10 TaxID=2304569 RepID=UPI001379E7D8 ------EQILNELSQMEGKVGFYYHNLVTGETY-GYREKEPFLPASVVKLPLMAAILLLRS -RGEADFREEILIHQDQKVPGCGAVQHMTGEVLDMETLGKLMITISDNTATNALLRHY-TV -PKIREAFLELGLIGTQFNRELWDLERE-ARGINNYFVPEEIGILLEKIYHKTLVNEESSI -WLDDIMRQQQI-NHKMGGHLIMDYPMAHKTGDEED-KAHDVGIVYAK--QPFVVCFASNE -VD--VPMYEDFIRRTTKALVE-- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium RIFCSPLOWO2_01_FULL_37_15 TaxID=1802622 RepID=A0A1F4UTC5_9BACT ---NLNKQIDIQLKKLGGDVTLRVKFLNTKEEI-KVNQDFQFWAASVIKIPIACEFFRQVN -EGKINPETKTKIKAENRVEGSGVFKLLNKDDFTYLDLVTLMLDISDNAGTNEIVDII-GW -ENVEKYMHQLGLLNTTFRHKMMI--K--AGRGPNFTTAQDITILLEKLYNNEI---PGAA -QILAILKQQQD-RRRIPLLLPNDIEIANKTGSLEK-AVHDAGIIYSKNP---FIFVFLSD -DQEDKILTNEVLSGCAKLCFD-- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A149UMG1_9PROT -----AQIMTKTVSKQPGHFAVYAARSGEAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT -KGTLHPEDTIVVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVKAQGLNGIVFGRMIEDFDAN-DQGIRNQVSARGLGDFLQKLDSGQIVGKAQSQ -SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG -LP-DEQAGIRVLNTLSHQAYEYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces cavourensis TaxID=67258 RepID=UPI000E0CF304 -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDATVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI0004906DB1 ------RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA -FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Niastella koreensis (strain DSM 17620 / KACC 11465 / GR20-10) TaxID=700598 RepID=G8TCL6_NIAKG --hRLQQKIEETVKGLNGDIGVYVKNLRTGKVA-AFNSDTIFPTASMVKVTILIGIEDKIE -KGELEYHQQLEYRDSLYYAGEDILGSFKNGEIGLHKVMMLSLTTSDNTASLWLQSLAGNG -TRINQILDSLGLVNMRVNSRTPGREANRNQYGWAQTTPREMGTLMEKIYNGEVISKKASE -KMIRLLGRNYN-DEQAIAEIPPYIFVASKNGCVN-ASRSEILLVMAPHG-PYIFSVETKN -LKDNSNEAWELTRKLSTLCWNYf ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. Leaf176 TaxID=1736286 RepID=A0A0Q5NCF2_9SPHI --kKLQLKLNELVKGFNGDVGIYVKNLKTGKTA-SVNADTIFPTASMIKVPITCGIFSKIE -KGELDYHSELMYCDSLLYAGEDILGSFKDSEIALNKVLMLMITTSDNTASLWAQLLAGTG -TAINEVMAKNGLKDTRVNSRIAGRKDNQKKYGWGQTTPREMATLLTLIRDGKMINPAASE -RIYRNLIRIFW-DTEALSQIPPTVQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN -QKDTSNEGWTMIRKLSNLLWSYy ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. CNZ288 TaxID=2512147 RepID=A0A4Q8CWP7_9ACTN -hrTARSRIRRAFTEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIAVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Symbiobacterium thermophilum (strain T / IAM 14863) TaxID=292459 RepID=Q67QZ3_SYMTH -------TLNALVAGFSGTMGVWARSLQTDEVIqVGASDDTFPSASTIKLAIFYEVMRQAG -EGRLDLSEPRELRTEDKVPGCGVLRDLSPGILPLRDLATLMMIISDNTASNMCIDAV-GI -ESVNRSMDELGLTGLRLRWKFF---GAPAGQPVNAAVPSQLGRLMDMIVRRQVLTPEACD -EMLRVMKQVQSAARYLPGGSPEGPVIAAKFGSIT-GCRHEVGAVWKGGR-GFVFSVMTKD -CKERRVEDNEGVLAVGRAVA--- ->[subseq from] serine hydrolase n=1 Tax=Acetobacter persici TaxID=1076596 RepID=UPI000A36086B ----LAQRMAETVADQPGHYAVYAARSGQAPDV-CVNCDDLINAASTIKLFVLDAAYAAFA -KGTLHPDDTLTVHNRSLVGKGHFAYAQAGKAVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVNAQGLNGIVFGRMIEDFDAD-AQGIHNRVSARGLGSFLQKLNNGQIVGKTQSQ -SMIGIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVRNDAAIVTLPDGRQYILVVLTSG -LP-DEQAGIKVLNTLSHQAYLYf ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0011DE38F6 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A-like protein n=6 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1CWY3_9BACT ----LKKKIIEAIGTTIPEYSVMVKDLKNDFSI-DMNANTIFTGASVNKLPILGTLYYLAQ -KGDIDLDRQITIQPEDIQDTGQIRYDQPGTMYSVKTLSRLMMQKSDNTAAYILGRQVIGI -PKIQQLITSWGMTQTDMEN--------------NKTSNTDIALLMEKIYREKVANKALTL -EMLSFLKDGTI-EDRIPALLPKETVVYHKTGNGV-GFLHDVGIVVGPKT-TYYIGMFTSG -VP-DEAEAVRILATISRIVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Anaerocolumna aminovalerica TaxID=1527 RepID=A0A1I5GN18_9FIRM ---TLEERIKAELASYNGTMGIYVNDF-QGNKV-EINIDKEFETASTVKTYILGTLFDEVE -KGNKNLSDKLIYTQENEIEGSGILRSLDYGVLTVKNVATLMIIVSDNIGTNMMIDYL-GI -DTINAFMQSYGFTHTKLHNKIN---FD-IYDKLGTTTPRDYGKIFEMICKEELISPEASR -QMLEIFKKQHY-NSMLTKSFPQYIYVASKSGSMD-ACRNDGGIVSTPYGK-YVIVLFNKN -FTDPEHQATVFGSKVSRLIFDQy ->[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 3J3 TaxID=2606600 RepID=UPI00135C2CFA --kKLTEKLEKALAGFKGSAGVYVRNLKTDKFA-SVHSDTIFPTASMVKIPIMIGVFDKIN -KGELQFDQLLTYRDS-LKYDDGITGSFRDSTIPLPKVIHLMISLSDNTGSLWLQALAGGG -AAINQWMETNGFVNTRVNSRTPGRKQNQAIYGWGQTSPREMAELMVMIRQGKVISPSASE -RMYRYLGMQFW-DGEALSQIPPFIKTGAKSGAVNQ-AKSEVVMVHAPHGD-YVFCITTKN -QQQRDNEGYDMIRKVSEIIWNHf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Saccharibacteria bacterium QS_5_54_17 TaxID=1919228 RepID=A0A2T2QWJ4_9BACT --qEIRQELNEMLESADGSWSVYVRSFDQEEAAfEYGRDKVFYAASINKLPIALYALSQVE -EGKIGLSDKLEVTEEVKRPGTGILRLHEGLDVTVEDALTLMMAVSDNTAAKLMVRKA-GP -ENINQYLEASGLADTRLEVLPEGKFS------YGYTTAKESAQLLRGIHNAEYVSPEASR -KLLGMMGRNHF-SHGVRRYLPKDLKIANKEGSLED-NRHEIAAVMAE--RPYAICVFADE -LA--------------------- ->[subseq from] Serine hydrolase n=2 Tax=Cyanobacteria TaxID=1117 RepID=A0A1Z9Q274_9CYAN -----SGKWKQLAAQQDLKASAYMLILDDGRYA-AMNPERPMPAASAIKTPVLLAALELID -SGELHWNEPLTLTKELVGGGAGWMAKPVGSRFPTHETATEMIRISDNSATNLMIERAGGM -KXVNARFQALGLPSTEINNWLPDLDGT------NTTSARDLSRSIALVDTGESLSLRTRD -LFRDVMATSVT-NTLLPTGLLQGYRIYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG -PFND-PRSTNLIRAMASAM---- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. UBA8071 TaxID=2055764 RepID=A0A3D3TWY7_9SYNE ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRQLAAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. RS344 TaxID=2024886 RepID=A0A2E7LV02_9SYNE ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRQLAAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. Hv1 TaxID=1740090 RepID=A0A0Q0VLF6_9SPHI ---KLTKMLTELTKGFNGDVGIYVKSLKTGKVA-SLNADSIFPTASMVKVPITCGIFNKIE -KGELDYHAQLTYKDSLLYAGEDILGSFKSGEIWLSKVLMLMITTSDNTASLWSQSLAGTG -TAINELMEQNGLKYTRVNSRTPGRQANQKQYGWGQTTPREMATLLTLIRDGKMINPAASE -RIYRNLIRIYF-DHEALSQIPPYIQAASKSGAVN-AARSEVVLVNAPHGD-YVFCIATNN -QKQSNNEGYVLIRKLSKMLWQYf ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW86 TaxID=368491 RepID=UPI000E0EEF48 ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTKELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLIIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRRLAAAMA--- ->[subseq from] Uncharacterized protein n=1 Tax=Deinococcus koreensis TaxID=2054903 RepID=A0A2K3UYZ9_9DEIO ---------------------FCVHELGTGMIR-AQRADEVVPTASTYKLPLLLHIALLVE -EGALSWAQPFTLEDRHKSWGSGVLRDSVGLTFPLRDLCHLMTALSDNTATDLLLDTL-GL -DGVNRRLAGLGFEQTRLLPQHAAPGAGRPPLAVGVTTPAEMARLLRGIVLHELCSSASSS -VILGMLGAQHD-RSMIPRFLQPDWIYSGKTGSNED-LRADVGIVTDPQGRSFVLALYCQH -PT--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A0D6IR82_ALCXX --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase n=1 Tax=Sphaerobacter thermophilus (strain DSM 20745 / S 6022) TaxID=479434 RepID=D1CA76_SPHTD ---SLAERIDPLVAEVPAEIGIVVALPDGTRLY-EYQPDRLFEAASLYKLGIMVELYRQRE -AGWISFDETITLLPGYYEEGPDVYGEAIGTAVPIDDLLWAMIAASSNVASHALLDRI-GN -EAVNATMAGLGLVQTEIR------------------------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb64 TaxID=1848691 RepID=A0A2S8ZU09_9MICO -------SIAEIFADADAEGFLHAREIGTGPEV-DSGADEPVVLASVFKILVLTAYVRAVA -AGTLDPTERTTVTARYRIGGIGTAGFSDDVQASWRDLAQNMMTMSDNAATDVLYHRL-GG -DAVDRVIADLGLRNTRLIGCCEDLFAALDPARTSASTPRDVTTLLNALWTDTAAPAEACA -QARAIMAQQIW-PHRLTSGFPNGVTLAAKTGTLPR-WRNEAGVVTYPDGRQYAVAVFTRA -HTLD-ERLPRVDASIGR------ ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A370ACM7_9LACO ----VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH -QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV -SAINSEVAQLDLKDTKMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ -TMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGA-FIMTVMAAD -GEREA--QTTALN---------- ->[subseq from] Beta-lactamase class A n=1 Tax=Desulfotomaculum arcticum DSM 17038 TaxID=1121424 RepID=A0A1I2ZK77_9FIRM ----LDQSVSEYLVAQEGTYGLYFIDLKSGEKF-GYNQYTSFHAASTFKLPMNLYLYTQAE -KEKINLAQKLTYQSRHAEGGTGILKNYPPGKYTIKQLATYSIVNSDNIATNILLERL-DR -KKVKSYMRDLGGKVVE--------------DDNNVTCPHDLALYMQKTIEFYRTGSPEAK -MLTENLFAAEF-KDRIPAAVPPGVKVANKIGNWPTGTYNDVAYVEHPVR-PYILAVTCSG -TP-GYGSAVPVIRQVSKMIYEY- ->[subseq from] Serine hydrolase n=1 Tax=Lachnoclostridium sp. TaxID=2028282 RepID=A0A352P9A9_9FIRM ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AIHADEAFETASSIKAYILACLFDELE -KGNKSLEDIIEYKEEHAVDGSGVLAAEPGVKLRVKDAATFMIIVSDNIATNMMIDYL-GL -EKINQCIKTLGCKDTVLHNSIH-FER---YDRLGTSTPRDYASIFIRLAKGELISPRADE -MMLGILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVYGARVSRMILDQf ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=A0A1I6RF85_9PSEU ----TEQRIREVLADAGAQGWVHAVRLGGGHEL-GSGADDLVVTASVYKLPLLVALARAFD -AGTLDPRETIRLDPTACTPPTGVAIFQDPVRLSWRDLAASMVSVSDNAAADVILGAI-GL -DAVTETLADLGLERTRVVGGTADANAAYDPSYASATTPREMTRLMELIWADAVASPQQCA -FVRRLLGQQAW-MHRVRAGFPRGVQVSGKTGTIG-AVRNEVSVVEFDGEAPVAVAVFTLA -ARADLPRVDEAIAECARLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter cerevisiae TaxID=178900 RepID=A0A149V9B1_9PROT ----LAQIMAKTVTKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTIKLFVLDAAYEAFT -KSTLRPEDTMTVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSAVKAQGLNGIVFGRMIEDFDAN-DQGIRNRVSARGLGDFLQKLDSGQIVGKAQSQ -SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSD -LP-DEQAGIKVLNTLSHEAYTYf ->[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ishikariensis TaxID=137265 RepID=A0A1H3TB82_9ACTN ------DRIAGIFAAVGVDAQLHAVDVDRGTEL-SVRADEPVVLASIFKILLVLEFARQAA -AGQLDPTERVVVRAEDRLGGWGTSGCADDAELSLRDLAYFAMAFTDNTAADLLLRRV-GP -DVLPLLTAELGLTTTRITGGPRELLEVFDPDKTTSSTPREVTRLLELIWRDEAGPPAATA -MVRALMGRQIF-WTRIASGFPPGVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALAIFARA -HQLDFRRVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia pseudobrasiliensis TaxID=45979 RepID=A0A370HZV6_9NOCA ---------------AGVQGWLHARCLDCGAET-GWRADEPVVLSSVVKVPLVLELARQIA -AGQLDPTDRVRATAADRLGGPGTSGCRDDVEYSLRDAAYLALSVSDNTAADLLFDRV-GL -DNVRSRVHELGLTRTRVVGALRDLLIIMDPGRTSASTPREMTRLLELIARDEAGPPAACA -WLRELMGAQLN-QARLGSAFGDEVTLWSKTGTLP-GVRNEIGVVRSPDGTRCAVAVFTRA -AVDRAPRVDRAIGAAARAAIE-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Microbacterium azadirachtae TaxID=582680 RepID=A0A0F0LMY5_9MICO ----MTTSIAEIFADADAEGFLHAREIGVGPEV-DSGADEPVVLASVFKILVLTAYVRAVS -AGTLDPTERTTVTARYRIGGIGTAGFSDDVQASWRDLAQNMMTMSDNAATDVLYHRL-GG -DAVDRVIADLGLRNTRLVGCCEDLFAALDPARTSASTPRDVTTLLNALWTDTAAPAEACA -QARAIMAQQIW-PHRLTSGFPNGVTLAAKTGTLPR-WRNEAGVVTYPDGRRYAVAVFTRA -HTLD-ERLPRVDASIGR------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=UPI0008543D93 ------ERIREVFAGAGAEGLLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFLAISVSDNSAADLLLARV-GL -DTVRLLARELGLGGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA -HVRDLMARQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART -RDASRPVVDAAIGATARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Flavihumibacter sp. SB-02 TaxID=2676868 RepID=UPI0012FC7240 -------------QGFKGDIGFYIKNLKTGKVA-SYNADTVFPTASIVKVPILVGILDKLE -KGELNYHDQLTYADSLYYAGVDILGSFKDGEIELSKVIMLMCTTSDNTASLWLQQLAGTG -TRINQLMDELRLPNTKVNSRTPGREEIRKQYGWGQTTPAEMATLFEKMLQREVINGHASD -KMMRILGRNYW-DEEGLSKIPPGVFVASKNGAVD-ASRSEVMYVNGHK-TPYIFAVFTKN -NEEPTNEAWELTRRMSDFVWTYf ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N5 TaxID=2575515 RepID=UPI000E0E1FAA ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTKELVGGGAGWMATRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINALFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRRLAAAMA--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces puniciscabiei TaxID=164348 RepID=A0A1D7Y4Q3_9ACTN -------RIRAAFAEAGVTGRLHALDIDSGAQI-DVGADQPVCTASVHKLCLLVTLHELAA -TAHLDLGEQIDCEPAGRTAGPTGLAAMLDPVMSLRDVAYLMMAVSDNASADLLLRRV-GL -DAVNRTTARLGLTRTHAVHTFGELFAALDPDRTNRSVPRDMTRLLGAVWRDEACAPEHGA -SIRRLLGLQVW-PHRLASGFPDDVHVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRT -ANATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C105KSO15 TaxID=1776047 RepID=UPI0007405DC1 ---TLEKRIEAEIKSYDGKMGIYLDDF-HGNVI-SIHADEAFETASSIKTYILACLFDEVE -KGNKSLEDIIEYKEEHAVDGSGVLAAEPGAKLRVKDAATFMIIVSDNIATNMMIDYL-GL -EKINQCIKALGCRDSVLHNPIH-FER---YDRLGTSTPGDYASIFIRLAKGELISPRADE -MMLEILKKQHY-NSMITKDFPPFISVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ-525 TaxID=418855 RepID=UPI00056309EF -hrTARSRIRRAFTEAGVTGFLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIAVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Flectobacillus major TaxID=103 RepID=UPI000414306D ---VLETKLQNLVKGFHGDVGIYVRHLKKNKMA-SIQPDSIFPTASMIKVPITIGLFNKIE -QGLLDYHAVLTFRDSLLYAGDDILGSFKDGEIALAKVAMLMITTSDNTASLWCQAMA-TG -TGINEWLDSNGFKDTRVNSRTQGREPARKKYGWGQTTPREMAELFVKIREGKVISPAASE -RIYRNLIRIYW-DGEALSQIPPTVQVASKQGAVNQ-SRSEVLLVNAPSGD-YVVAVITKN -QKERTNEGYVFLRAISKTVWEHf ->[subseq from] Class A beta-lactamase n=1 Tax=Megasphaera sp. BV3C16-1 TaxID=1111454 RepID=U7UIN5_9FIRM ----------------AGELAVYCRRLGGGEPF--LLRDRPMAAASLIKIPIMIEAFRQER -AGRISFSARWPVRAA--VPGGSFYTLPINTPVTTAVLIEHMIVESDNTCANMLLDIL-GM -AAVNDCIDGLGLKGTRLRRKMMDFTAA-AAGRENVTTPGDMGRLMTLLAEGRCLGRRADA -AMCGILSRQED-NCVIPAQMVRSLRIDHKTGELA-GVYHDCGILYAPQGK-LILCLMADG -IKNEA-QAIYDMSYLARA----- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. CPC100 TaxID=2024879 RepID=A0A2D5RB38_9SYNE ----LSKRWQTLAAEQDLDVSAFMLVLDDGRYA-QLEPDTELPAASSIKTPILLVTLEELD -AGRLSWNEPLQLSQTVVGGGAGWMAKPLGTRFPTHEVATEMIRVSDNTATNLLIERLGGR -EILNARFNALGLSATKVNDWLPDLKGT------NSTSARDLARSIALVDTGEALSIRSRD -LFREVMGTSIT-NTLLPRGLLRGYKVFNKTGDIGI-AYADAGLIELPDGSRAVAAFLVKG -PFND-PRSTELIRKLAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CS090A TaxID=2162710 RepID=A0A2T7KKZ0_9ACTN ----VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDEQVPMGSVYKVALMAAFCRLAD -EGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -EAVDGMCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS -FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. MED-G134 TaxID=2518987 RepID=A0A520LHE1_9SYNE -----SQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLMLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAVNARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSVT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRQLAAAMA--- ->[subseq from] Serine hydrolase n=2 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PP99_9PSEU --------------------------TPPGREV-DVDADEPVVMASVYKLVLLVALCRRFE -DGLLDPQSTVRVNPASCTPPTGISTFLDPITMSWRDLAASMMTVSDNAAADVILGEV-GL -DAVQRLLVEEDLTGTRIIGGTADVAAAYNPVYTSATTPRDMTRLLSLIWSDAVVSAEQCA -FIRRLMGMQVW-SHRIRAGFPGDVRVSGKTGTIG-AVRNEIAVVEYAGELPIAVAVFTFA -ARADLPAVDAAIAEAARLAV--- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. FWC2 TaxID=69664 RepID=A0A2G5QS66_9CAUL --kNLQKRIEAIAARAPAVLGVAVEDLGTRQLW-AFNGDRRFALGGAARIPILAAVMAETE -AGRLPLDEIVTVRDVDLSPPSAVADAWPGRNWSIAELETLA-RQGDNTALDLLIKRVGGP -GAVNGWLDVKRIEHVSVDRYRRQIATERATDPRDTATPIGLLRLMEAFTNRELFYKPDPA -RLLG---RD---AGYLAKALPAGARIIQLAGAARQPTNHAAAFVELKDGRRIAFVVFLTA -STADAAQREAIITDVGEAVLKEf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. YC504 TaxID=1775132 RepID=UPI0013EC1488 -----EQRIREVFAEAGAEGVLHAVPVGDTAEV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCVDDIELSLRDLAYFALSVSDNSAADLLLDRV-GL -DTVQLLAKELGLTRTRIVGGPREVLEVLDPQRTNSATPREITWLLRLVWRDEAGPPQACA -QVRELMARQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART -REASRTAVDSAIGATARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Cupriavidus sp. USMAHM13 TaxID=1389192 RepID=UPI0008A6B490 ---RVEAGLAPLLAATPARVALSLR-LRDGSIVlERAASCAMPSASLVKVPILLAMLEQVG -QDRLCLAQEMSLAGIERVGGTGILAQLPSVRLTLAELARLMIVLSDNVATNALITLL-GF -DAVNGWCERAGLAQTRLQRRMMDAAAR-AAGRDNFTSAGDTAAALGWLLRGDTLPAPLRA -FGLALLADQRE-RAHFGAALPAAARLANKTGQLP-GLRHDAGILTVGDQ-SVVLAVLADG -FTDPRTARE-------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=UPI000CB39FD0 ----VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH -QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV -SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ -AMLTILKANTD-HSKLVKNLPKRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD -GEREA--QTTALN---------- ->[subseq from] serine hydrolase n=1 Tax=Pseudoxanthomonas suwonensis TaxID=314722 RepID=UPI00138F163E ------------------------------------------------------------- -----------------------------------------------------------GE -PRLQALADALGVPRAELDATLEQVFEDYYARGLNSATLPAYGRLLARLAGGELLSPRSTD -LLLGHMRAINTGSRRIQAGLPPDADFAQKTGTQLQ-RACNVGLLDPGGRDGATVVVACAE -RFGELEQAEQAFQALGRALAD-- ->[subseq from] Uncharacterized protein n=1 Tax=Vagococcus fessus TaxID=120370 RepID=A0A430A7S2_9ENTE ---EVRSALDTQLKNVYGTNSYYFQDISVQQAF-ETN-DQKQLAAGMINLYIMQMLFDKVE -QGKMELSGSYKLTSKDKTSGTGVLKDMSDGTLTNEKLVEYMLVDSDNTATNVLINRLGGL -GEIEKFIQSKGYSNTHINRKMADMG-AISQGKENYTSVKDTGNLLSKLYKHDLVSKEMDD -KMLAILSKTKD-KAKLRKDLPKDVTVYSNSGQFSYGVINDAMIVKTKDKT-FVLVVLMQN -GDQY------------------- ->[subseq from] serine hydrolase n=1 Tax=Heliobacterium undosum TaxID=121734 RepID=UPI001371A16D ----LKQKIQGYLNTRPGQVNLYVQDLTSGAKM-DIAGDEIHRTASTHKVPTVMYLYSLAA -QGKVDLDAKLTYTSQYYRQGTGILQTKPYGGYTLRELGRLSIVYSDNVAWVMLLDYL-GR -ENVNNYMRSLGANVTGSDANGYF-----------ITTPCDMGKYLGALLVFKDAYPQLGG -EIFSAMQNTIF-NERIPAKLPNGTVVAHKIGSLND-SIHDMGIVFANNR-PYIISLYSKN -AW--EAASNETLAQVSKMVYDH- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG03_land_8_20_14_0_80_39_12 TaxID=1974879 RepID=A0A2M7BBR2_9BACT -----RQAVEQIIEPLRGTYGIYFRDLEKGDAF-SINSLEKMTAASLIKMPTLLTLYREAD -AGRINLDTIYKLQAADRRGGAGSLIGRPEGSVSYREMAKLMGEQSDNTAFNIVANKILGG -EKIQNTINLLGMRQTSFN--------------DNITTPEDMGLLFRKLLQEKVVTDKSRD -EILSFITNTIW-ETRIPAGIPKGIKVSHKIGSDI-GVVSDAGIVFAK--KPFILVIMSQN -ANE--IEAGKALPEIAKKIYEMw ->[subseq from] serine hydrolase n=1 Tax=Asanoa ishikariensis TaxID=137265 RepID=UPI000B86C0D8 ------DRIAGIFAAVGVDAQLHAVDVDRGTEL-SVRADEPVVLASIFKILLVLEFARQAA -AGQLDPTERVVVRAEDRLGGWGTSGCADDAELSLRDLAYFAMAFTDNTAADLLLRRV-GP -DVLPLLTAELGLTTTRITGGPRELLEVFDPDKTTSSTPREVTRLLELIWRDEAGPPAATA -MVRALMGRQIF-WTRIASGFPPGVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALAIFARA -HQLDFRRVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Runella sp. CRIBMP TaxID=2683261 RepID=UPI0014120C83 --kKLTTQLQEAIKGFRGDVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIA -KGELRYNAILTYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG -KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELFAMIRQGRAISPDASD -RMYRNLTRQYWDGEGL-SQLPPDIKTASKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN -NLTSQNEGYVLLRKISKLLWNYy ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536JVS1_9CHLR ----------AALASLPGEAGAFASDPDGRAIF-CEREDDLFPSASVIKLPLVMTLYADAA -RRLVDLDELVSVG--DRVDGTGVLRHVPDVELSLRDLATLAIIVSDNTATNRLIERI-GV -DRVGERMREWGCPLSRLSRKMYDFEAA-KRGSENVMTARETVSLLLRLQRGECEDRATSD -AVVVLLEQCQD-RTMLLRYVPDTTNAPHKTGTLDE-SRNDAAIV--PGERPVTVAAFTRK -LRDT------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. MJM8645 TaxID=1120523 RepID=UPI000AD113A2 ---TARARIAAAFADAGVSGRLHVRDLDTGTEI-ALDADTPVSTSSVHKLCLLVTLFREAA -AGRIDLTRQVDVPAAGRTSGTGLAAMLDAARLSLRDLAYLTVAVSDNAAADVLWDEI-GL -DTVNRTMADLGLTRTVAVHKLRDLIAVLDPTFTNRSTARDMTTLLAALWHGDACPGEHGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAIFTRA -AATTLPAADAAIGTTARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Dyadobacter koreensis TaxID=408657 RepID=A0A1H6U0N9_9BACT --qKLVSKLEEAMKGFRGNAGIYVKHLKNNRIA-SVNSDSVFPTASMVKIPIMVGIFEKIR -QGGLKFDQVLTYRDSLKYDDGVVGSFKDSTKIPMPKVIHLMISESDNTGSLWLQALAGGG -EAINQWLETNGFENTRVNSRTPNRKQAQATYGWGQTTPKEMAKLMLMIREGKVISPDVSE -RMYRYLGMQFW-DGEALSQIPSNVKTSAKSGAVNQ-AKSEVVMVHAPHGD-YVFCITTKN -QLERSNEGYELIRKVSEIIWNHf ->[subseq from] Uncharacterized protein n=1 Tax=Selenomonas sputigena (strain ATCC 35185 / DSM 20758 / VPI D19B-28) TaxID=546271 RepID=C9LY50_SELS3 --eALRADFSAILAPKSPDCSVFLLRPREEKEP-LLYQSHAMQPASMIKLFILAYAMQQAK -DGTLSLAEPLSITEANIVGGAGQLNWYDRGKLTIEQLLERMITDSDNTATNILIDRL-GI -ENIDGYIRQKGYADTRLQHKMMLSNQG----RPNLSSVKDIGTLLSLIYRGECVDYEHDK -KMLQILSRQKD-KDCLPSALP-AFLVANKTGEIT-GVYADGGIAWSDAGD-LILVVMDEN -CR-DRQETIALFQRIAQRA---- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C12C24 ----VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVQ -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTRMARRLMDTA-ALRAGHDNDTSVRDVATVLKRLANRRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS -GER--TAQTSAMNDLGQVLYR-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0009706CE3 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADRS-VVLAVLAVG -FTLQGGEGAALLGQIARAV---- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TSRI0281 TaxID=1718998 RepID=A0A1Q4Z900_9ACTN ---TAEARIRAAFDEAGVEGFFLAREIDGDRTI-GVSADEPVVLASVFKIPVALAYAREAA -AGRLERTERLAVDARYRDGGIGTSGCADPIEMSLRDLVHLMLTMSDNAATDVVLARV-GL -DTVNGLLRELGLEHTHLIGGCLELISVCVPELTTRSTARETAELLARIWRDEAGSAVACA -EVRAVMAQQIW-PHRLGSGFDDSYRLAAKTGTLP-GWRNEAGVIEHPGGGRWAVAVFTRS -DTPDNPRADRVIGQVARLAVDE- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoanaerobacterium thermosaccharolyticum M0795 TaxID=698948 RepID=L0IHH2_THETR --qELKNNIETLLSQHPGKYGVYFIDLNSGQTF-NINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGADVIPY--------------TSNVTSPRDLSLYMENLLNYANAHSSTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSR-PYILTVMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536LXG5_9CHLR ----LEGELLRIGSTYSGKWTYALTDMSSGQKI-GHRQDDVMPTASLIKVPVLTALYRAVH -EGRLRLTDRIRYGDEHRCLGSGVLSRLTPGVMTVRDAAVLMIIISDNSATNIVIDLV-GL -DQVNETMRCFGLGRTTIFQRLGDTKAGLDARKMSVSTAGEMTRLLELIARHEAVPPEASE -DMLRIMRRQDY-RHELSRLLPTENWVAEKGGSFLNGIRTSGAIFNGSRG-KFVMSVFCEG -GTGP------------------- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N26 TaxID=2575513 RepID=UPI000E0EB2D9 ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEKLVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRQLAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Paenibacillus sp. 7884-2 TaxID=2022552 RepID=UPI000BA733AF ----------------------------AEGTI-QFNANTPRKAASVVKLFILAEVLQQIE -AGRIQREQLISIKPEAMVEGAGVINYLTKHNYSYQNLLELMIIVSDNTASNILLDMI-GI -DRINHSIKKLGCQDTIIKRKFMDQEA-QASGNENITTAADIVHLLKLFSSDNGYSKNLRQ -EVRRLLKNQQF-NNKLAAYQMCKLNIYHKTGELP-GVEHDVAIMESTGRK-LEVAVLTEG -WEN-NGIAQHFIAEVGRYLMNY- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. S8 TaxID=1837283 RepID=A0A1W5YTE0_9ACTN ------RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT -DAVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPSSCA -FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Inediibacterium massiliense TaxID=1658111 RepID=UPI0006B69071 --kNLKNKIENIINSIDGHKGVYIKDCSTHEVI-EIHENRKFHAASTIKLPILYDALLQIQ -NKKLSLNDTYQLKSSDIVDGSGILKLHIGLEVTLKDLLTLMIDVSDNVATNILHDLL-GK -DHINGSIKNLKLQNTFFARKLMISDSN----SYSYTTAKDLGILLEEFLICKNLNQAMAN -IGLHILSNQQY-NDRISHHL---------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. HBUAS56010 TaxID=2571127 RepID=UPI0011774DB6 ---TLEKRVEAEIKSYDGFMGIYLDDF-HGNVV-KVHADETFETASAIKTLILASLFDEAE -KGNASLTDMLKYKEEHIVEGSGVLSALTPGALRVIDAATFMIIVSDNIATNMLIDYL-GI -DTINNCIKRLGCKDTILYNPIHFEQY----KRLGTSTPADYASVFIRLAKGELISTGADS -QMLEILKQQHY-NSMITKDFPPYITVASKSGSMD-GCRNDGGIVFTPYG-PYVIVMFHKQ -FSDAGHPAMVFGARVSRMILDQy ->[subseq from] Beta-lactamase class A n=1 Tax=Prochlorococcus marinus (strain SARG / CCMP1375 / SS120) TaxID=167539 RepID=Q7VBF0_PROMA ---TLESKWKEIDTKNNALKASGYVLLEDGRYA-ELNSNQIAPAASTIKIPILLICLKMVG -SGELKWNEKVTLTKDDVAEGSGWIRQPLGKEFFIHEIATEMIRVSDNTATNLLIRKIGGI -NTINQRFNMIGLKATKINSLLPDLQGT------NTTTTKELVKILELALKKNFLSIEARD -LFRDVLSTSVS-NKLIPDGVLEGLRVFNKTGDIGT-AYGDAALIQMPNNTNVFASFIVQG -PFND-QRSPELIRKLTAS----- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JFG2_9ACTN --------------EADVSGRLHAVDIDTGREL-GVGADDPVVLASVYKVPLLVAFFRLAA -RGVLDPAERITLRPDERTEGTGLSVMLDDVTMSLRDLALMMITVSDNAAADAVYARV-GR -DEVNAALDGLGLPGIRVTGDGRDLFDPLDPSRTSAGTPRELTGLLSLIWLDRAAPAAECA -LMRRMLGHQVW-PHRLSAGFPDDIRVSGKTGTLLT-LRNEIGVVEYPDGGRYAVAVFTRA -AEAVAPRADAVIGATARIAVE-- ->[subseq from] Putative beta-lactamase family protein n=1 Tax=Synechococcus sp. WH 8109 TaxID=166314 RepID=W0H0L6_9SYNE ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRRLAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N32 TaxID=2575514 RepID=UPI000E0F6CF2 ---------ELAAQQSDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEELVGGGAGWMASRPLGSFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFN-DPRSTELIRRLAAAMA--- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis vancoresmycina DSM 44592 TaxID=1292037 RepID=R1G1Q4_9PSEU ---TVEAEIDGVFAAAGARGFLHAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA -AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRI-GA -AAVDRVLADLGLRRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGEPAACE -RVRSMLARQIW-PHRLSSGFGSDVAVAAKTGTLP-AVRNEAGVVSFPDGRRFAVAVFTRA -NSERQPAVDAAIGKAGRLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536RI40_9CHLR ---DLTKQLDGLVGSFPGGAGIWIADPTVATPLfAHDPEEQVIAASLYKLGVLAEAERRVD -AGELHYNDTITIEPEDITTDGSF--EYAGTELTLDEALEAMITVSDNGAALALWHVL-GG -ANIDATLEKAGVKNFHVA---------FDDTEDNWATPHAIGTYFTLLAKRQLISPAASD -RMLARLERQQI-NDRLPAQLPADVVIAHKTGNLA-GVTHDAGIIFTKTG-PRVVVVMTWD -AL--DEDAANFISSIGSLVYS-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID8374 TaxID=2690354 RepID=UPI00136C9A21 -----EAAIRALFDDAGVRGWLHVAELEHSARV-VIDPDEQVPMGSVYKVPLMTAFWRLAD -AGRVDPLHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -DVVDGVCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAEIARLLRAIWTDEAASPESCS -FMRAAMGTQPW-THRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetaceae bacterium TMED241 TaxID=1986836 RepID=A0A424K032_9PLAN ---ALSQRWTQLAAAQDLEASAFLLVLDDGRYA-QMQADRAMPAASSIKTPILLVSLEQID -RGDLRWNEPLTLTKPVVGGGAGWMAKPLGTRFPTYEVATEMIRISDNTATNLLIQRAGGK -ERLNSRFQALGLTATKVNNWLPDLDGT------NTTSARDLSRAIALVDTGGTLSLRTRD -LFRDVMGTSVT-NTLLPKGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRAMAAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Arthrobacter sp. 18067 TaxID=2681413 RepID=UPI0013567D54 -------QLAEIFASAGATGSVHAREIGDGPEV-SLNPDGPVVLASVFKVPFAVAYSREVS -AGRLEETDRTTVTSRYRVGGLGTAGCADDVEMSWRDLAKFMMTMSDNAATDVLFHRI-GQ -AAVDAVLDDLNLKHTRIVGCGEDMDVILDPARTPSSTPRDIVTLLDAIWTDTAGSPEVCE -RVRSMMAQQIW-RHRMATGFDGNIVVAGKTGTLP-AIRNEVGVVTYPDDRQYAVAVFTKA -DTNPQPAIDASIGKAARLAVD-- ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter thermocopriae TaxID=29350 RepID=UPI00056C682A --qELKNNIQALISQYPGKYGVYFIDLNTGQTL-EINGYDSFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMEKLGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPAR-PYILTVLAND -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AIX7_9CHLR ---DLTKQLDGLVGSFPGGAGIWIADPTVATPLfAHDPEEQVIAASLYKLGVLAEAERRVD -AGELHYNDTITIEPEDITTDGSF--EYAGTELTLDEALEAMITVSDNGAALALWHVL-GG -ANIDATLEKAGVKNFHVA---------FDDTEDNWATPHAIGTYFTLLAKRQLISPAASD -RMLARLERQQI-NDRLPAQLPADVVIAHKTGNLA-GVTHDAGIIFTKTG-PRVVVVMTWD -AL--DEDAANFISSIGSLVYS-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Firmicutes bacterium ADurb.Bin419 TaxID=1852892 RepID=A0A1V5LU53_9FIRM --nELKSELEKYISGFQGQYGIYFIDLENNYEF-GINDTDEYIAASTVKVPLNYYVYREIA -DGEVDPEKTLAYNEADFEGGTGILQKLEGKTYKIKYLLELSITHSDNIATNMLLRYF-GR -KTLKKYMRAIGGTVV--------------DDNKNVSCPKDMAVYLKKIYEFCNSNGQLGE -ELKHNLCNTMF-NDRLPKLLPEEVEIAHKVGNQI-GAVHDVGIIYTE--KPYILAVMSND -VV-SDEESNNVIAEISKKVYD-- ->[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=1 Tax=Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9) TaxID=1198114 RepID=E8X686_GRATM ----LEGRLREIAAAHHGKVAVFAENLKTGETV-GLDADKVVQTASVIKLTILFDAMEQVR -AGKVKLDDAIVLKKSGQVGGSGILQLFDTPLLTLRDVLMLMITQSDNTGTNLAIDKL-GL -ANINGETRALGLKNTWLYKKVFTPATPMPADQKGKTTGREMAKVLERIYKCQFITAPKCT -EMLGMLNKQGS-RDGVPRYLNNDSAVGNKTGALE-AVRADAGIVSTKAG-PVVMCLFTYE -NATADNEGEVTIAKMSKAIVEAw ->[subseq from] Beta-lactamase class A n=1 Tax=Tepidimicrobium xylanilyticum TaxID=1123352 RepID=A0A1H2RB10_9FIRM ---SLEARINAEVFNFSGKLGFYASDF-KGNII-GVNSQEKFESASCIKVFVLTELYRQIH -EGKVSRNDLLEYTEEHFVVGSGVLRDLSYGILDAKSIATLMIIVSDNVATNILIDLL-GI -DNINNTCQNLGFKDTVLHNRI-DFNKY---DKLGTTTPKDYGLFFEKLYKRELWSQEISQ -EMIDIFKRQHY-NTILTRELPQYISIASKSGSMD-ACRNDGGIVFTPYGG-YVICIFTKE -FNDNDHESYRFGAKISRLVFDQy ->[subseq from] serine hydrolase n=1 Tax=Thermobifida halotolerans TaxID=483545 RepID=UPI000839772C ---ETHERIAALFDRAGVDARLHAVDLATGAEV-GLRADDQVVIASMFKILVLLEFARQVV -AGQVDPTERVTVSRENRLGGWGTAGCADDAELSLRDLAYFMMSVSDNTAADLIIRRI-GL -DTVQLLAAELGLARTRIVGGPHQVLEVLDPAHTTSSTPRELTRLLRMVWADEAGPAEACA -TVRACMARQIF-WTRIASGFDEGVRVSAKTGTLPS-LHMECGVVEYPDGGRYAVAVFAQS -RRLDLRDVDLAMGRAARTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Thermoanaerobacterales bacterium 50_218 TaxID=1635288 RepID=A0A101F7M0_9FIRM --rSLEQEIRKLLAEEEGTYGVYILDLHTQQFC-GINQEVVFHAASTFKIPMNLFLFQQIA -LNKINPQLKLTYKPQHYEGGTGILQFRYGTSYTIYELAKYSMVYSDNVATNMLLGYL-GR -KNVKDFMRSLGGKVV--------------DDRRNITCPRDMAYYMKALVAFWENYPEYGS -ILLNHLENTVF-NERIPKLLPSGTRVAHKIGNWATGSYHDVGIVFHPTH-PYIISLFSKG -VP-DRTHCFRVLQNLSLLVYN-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C07D76 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMRDAAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID2119 TaxID=2690253 RepID=UPI00136ABC66 ----VERTIRSLFDDAGVRGWLHVADLHRPSAGvVVDPDEQVPMGSVYKVALMAAFCRLAD -AGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -EAVDGMCAELGLPHTRIRGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS -FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. K36 TaxID=2305439 RepID=UPI00109D492F -------------------------GVDDGPEV-AIGADEPVVLASVFKILVLTAFVRAVE -AGELDGRERTTVTARYRIGGVGTAGFADDTEVSWRDLALNMMSMSDNAATDVLYHRL-GA -AAVDRVITDLGLHRTHLIGCCEDLFAALDPERTTRSTPREVTTLLDSLWSDRAAPATACR -QARDIMARQIW-PHRLSSAFPSGVQIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASL-ADRQPRVDASIGAAAYA-- ->[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ350 TaxID=2709799 RepID=UPI0013EBB748 ---DIEASLSQLIEDAGANASFAYRYLSSGWDF-SVHGKEPHTAASMISLAVLTQLFDRID -AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM -DAINSEVARQGLEGTKLERHMMDTEAQ-KEGRENRMASDDAAAILNAIAQGAFYNEELSD -FAYDLLSQQKS-DSAVKDALPEGATYAFKSGSLEN-VYNEGGIVFG--EHPYVFVAFVEG -VD--EEEATALVKDAAALV---- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. UW106 TaxID=368495 RepID=UPI000E0FB173 ----LSQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMPAASSIKTPILLAVLELLD -QGTLQWNEPLTLSQELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGM -EQINARFQALDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD -LFREVMGTSVT-NTLLPTGLMRGYRVYNKTGDIGL-AYADAGLIELPDGRRAVAGFLVKG -PFN-DPRSTELIRQLSAAMA--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNQ329 TaxID=1298879 RepID=UPI0004867176 -----------------VAGQLHARDIDTGAAL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTTAVDVPAAGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDTV-GI -EAVNRTMTDLGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLAAVWRDEVCTGAYAA -DLRRTLGTQTW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Microbacterium TaxID=2609290 RepID=A0A259SI12_9MICO ----TATSIAEIFADADAEGFLHARETEAGPEV-DSGADEPVVLASVFKILVLTAYVRAVA -AGTLDPTERTTVTARYRIGGIGTAGFSDDVQASWRDLAQNMMTMSDNAATDVLYHRL-GG -DAVDRVIADLGLRSTRLIGCCEDLFAALDPARTSASTPRDVTTLLNALWTDTAAPAEACA -QARAIMAQQIW-PHRLTSGFPNGVTLAAKTGTLPR-WRNEAGVVTYPDGRQYAVAVFTRA -RTLD-ERLPRVDASIGR------ ->[subseq from] Peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacter kivui TaxID=2325 RepID=A0A097AT79_THEKI --qELKNNIQALISQYPGKYGVYFIDLNTGQTF-EINGYDLFIAASTYKVPLNFYLYTLIT -DGKIDPNMKVQYTQADYEGGAGSIQADPVGSYTIRELSRRSIEESDNIASNMIMRVV-GR -DNYIKFMEELGAYVIPYS--------------SNITSPRDMSMYMKKLLDYVNAHPDTAG -ELMYYLKNTIY-NDRISYPIPDEIEVAHKIGNLSN-VVNDTAIVFHPTR-PYILTVLAND -VDSDDSYAYTVIRQISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridia bacterium BRH_c25 TaxID=1734399 RepID=A0A101WGI8_9FIRM ---SLEARIKAEIYNFSGRVGLYVNDF-KGNIV-EINSEEKFETASTVKVFILAELYRQIY -EKKLTAEDILTYNKEHYVVGSGVLRAMDGVQLTVKNFAILMIIVSDNIATNVLIDLL-GI -DNINNTCNDLGLKNTVIHNRI-DFDSY---DKLGTTTPKDYGKIFEMIHNKELWSQELST -QIFEILKNQHY-NTILTKKLPQYIYIASKSGSMDN-CRNDGGIVHTPCGE-YVVSIFTKD -FKDK------------------- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. WAY2 TaxID=2663121 RepID=UPI00131F671B --------------------------------V-SVDGDDLVVTASVYKLPLLVALCRAFD -AGTLSPTSTVRVNPADCTPPTGVSMFRDPVVMSWRDLALSMMTVSDNAAADLVLGGV-GL -DAVDRVLTDLCLARTRIVGGTADAHRAYDPSYASATTPQEMTALLDAIWTDRAVSPVQGE -FIRQVMAAQVW-QHRIRSGFPADVTVAGKTGTIG-AIRNEAAVVTFPGEIPVAVAVFTRA -ARADLPVVDQAIGRAAQIAVS-- ->[subseq from] Uncharacterized protein n=1 Tax=Peptococcaceae bacterium TaxID=2052179 RepID=A0A3B8NQD0_9FIRM --rSLEQEIRKLLAEEEGTYGVYILDLHTQQFC-GINQEVVFHAASTFKIPMNLFLFQQIA -LNKINPQLKLTYKPQHYEGGTGILQFRYGTSYTIYELAKYSMVYSDNVATNMLLGYL-GR -KNVKDFMRSLGGKVV--------------DDRRNITCPRDMAYYMKALVAFWENYPEYGS -ILLNHLENTVF-NERIPKLLPSGTRVAHKIGNWATGSYHDVGIVFHPTH-PYIISLFSKG -VP-DRTHCFRVLQNLSLLVYN-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces viridifaciens TaxID=48665 RepID=A0A5P2UXS2_STRVF ---AARARIAAAFAEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA -AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL -DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATSLPTADAAIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI00099BB8DE ----------------------------GGREV-AVGADTPVVIASVFKVLLVLEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFALSVSDNTAADVLLDRV-GL -DTVRLLAASLGLERTRITGGPRDLLEVLDPRHTTASTPRDITRLLRLVWDDTAAPPDACA -FVRDLMARQVF-RHRLVSGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGAHYAIAVFART -HDL-AASRTAVDAAIGRAAA--- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2G4IDB8_9BACT ---------DAELVRFPGKAGVWVKHLTTGEEA-GVHAHDTFNTASVIKIPVLVLAMQLAD -QGSLSLAERVTIGASEMRGGSGIFRYDPGLQPTFRDVLTQMIITSDNTATDIAIGKTGGV -DAVNRWLVASGYGGTKLSMTTADLFASDRSYWLGEMTPHATGRMLEAIQRCHVASKAACA -DMMRMMRGQQSGARRLPHFLN--VPVAHKTGDFPPALANDVGVIFTRSG-PVVVAFFANA -IEGPYGEAEDRIGRIAQHIVDYf ->[subseq from] Serine hydrolase n=1 Tax=Tissierella sp. P1 TaxID=1280483 RepID=A0A265QC07_9FIRM ---SLESRINAEVYNFSGRIGLYANDF-KGNII-EINSDDKFETASTIKVFVLAELYKQIH -ENKINPHKILKYEKENYVVGSGILRDLDYGVMTAKSFATLMIIISDNIATNVLIDLL-GI -DNINNTCADLGLKDTILHNKID-FEKY---SKLGTTTPRDYGRFFELLYKKELWSKEVSE -EMIDILKKQHY-NTILTRDLPQYISIASKSGSMD-ACRNDGGIVYTPYGG-YVISLFTKD -FVDNDHESYRFGGKVSRLMFD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Rhodococcus jostii TaxID=132919 RepID=A0A1H5MFH2_9NOCA ---------------------------DDGADI-AVGADDLVVLASVYKLPLLVSLCRAFD -SGSVVPTATVRVNPADCTPPTGVSTFRDPVVLSWRDLALSMMTVSDNAAADLVLGQV-GL -ESIEQMLSELGMTSTRVIGGTADAHRAYDPSFASATTPRDMTTLLDAIWTGRAVPGPQGE -FIRQVMAAQVW-QHRIRSGFPSDVDVAGKTGTIG-AIRNEVAVVTFPGEIPVAVSVFTRA -ARADLPVVDAAIGHAARIAVT-- ->[subseq from] hypothetical protein n=1 Tax=Actinomadura flavalba TaxID=1120938 RepID=UPI0004782D89 --------VAEAFRAAGVTGRLHARDIDTGGVV-DVGGDEPVVLASVYKVPLLVAFYREAA -AGRLDPAERITLPAGGRSPGPTGTSVMLDDVLSLRDLALLMITVSDNGAADTIYDYV-GR -DTVNAAMAAFGLTRTRVTGNGRDLFAALDPTRTSASTPAEMTALLALIWRDEAAPPDACM -HMRRMLGLQVW-PHRLSSGFPDDVHVAGKTGTLPT-IRNEIGVVEYPDGGRYAVAVFTRS -LLAVLPEADAVIGTAARLAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=A0A1V0VY74_KITAU ---AARARIAAAFAEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA -AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL -DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATSLPTADAAIGTAARLAVD-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A223I0B3_THETR --qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] Peptidoglycan-binding protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A231VMD7_THETR --qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=UPI0010084935 ----VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDEQVPMGSVYKVALMAAFCRLAD -AGRVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS -FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVDFGDGSVYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Parcubacteria bacterium TaxID=2053309 RepID=A0A3A4V0Y7_9BACT --nSLENAVQSALSESTGTYGVVIKNLNTDEKY-YLNEHRVFKTASLYKLWIMAVAYEQIQ -TGKLQKDQILTEDVSSLNDASESAEKTEGTILSVTEALNKMITISDNYSALLLSAQV-KL -SNVALFLKNQNLTESNIGTEDKS---------YPTTTPSDIALFFEKLYKGELANEKYTK -EMIDLLKNQRL-NNKLPKYLPQNTIIAHKTGELYN-ITHDAGIVYTPTEN-YIIVVLSET -DNP--EKAVEIIGQISKNVYNYf ->[subseq from] serine hydrolase n=1 Tax=Rudanella lutea TaxID=451374 RepID=UPI000375EE57 ----LERDLRALLGAFRGDVGLYVRNLRTGETV-AINADTLFPTASTIKIPIQCGLFDKIH -RGELKYSAELVYKDSLHYDDGIVGQLKDGARLPLSQVVMLMETTSDNTASLWCQAMAGGG -AAINAWLDANGFAQTRVNSRTPGRAAFQKQYGWGQTTPRELAELLAYIRAGRAVSPDASD -RMYRNLCRQYWDGDGL-SQVPPEVKVASKNGAVNR-SRSEVVLVHAPHGE-YVYCLMTKN -AQERTNEGFALLRAVGARLWKHf ->[subseq from] serine hydrolase n=1 Tax=Dactylosporangium aurantiacum TaxID=35754 RepID=UPI0005254590 ---------EETFAAAGVRGRLHARDIDSGRSI-GVGADEQVVLSSIVKVLLVLEFARQVA -VGALDPAERVVVGAGDRFGGWGTAGCADDVELSLRDLAYFAMSISDNTAADVLLHRIGGP -DLLALLAAELGLTRTRVVGGPRQMLEVFDPRRTTSSTPEELTRLLGMLWRDEAGPPAACA -AVRGLMARQLF-WTRLRSGFPAEVRVAGKTGTLP-GLAMEIGVVEYPDGGRYAVAVFVDG -GRTPRIEVDTALGRAAAAAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pallida TaxID=145854 RepID=A0A1C6RJM1_9ACTN ------------FERVGVEARLHVVDVDSGREV-GIRADEQVVIASVFKILLVLEFARQAV -AGQVDPTERVLVRAEDRLGGWGTAGCADDVELSLRDLAYLTMSVSDNTAADLLMRRV-GP -DVVPLLAAELGLARTRVVGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRNEAGPATACA -MVRELMARQMF-WTRLASGFPPDVRVAGKTGTLP-GLHIEAGVVEYPDGGRYAVAVFAQT -QRLTARDVDLAMGEAARTAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Gordonia terrae C-6 TaxID=1316928 RepID=R7Y8U0_9ACTN ------------------------------VEF-SHDADAPVVLASVYKLAVLISLCRLAD -RGDIDLAASITVEPTRWAPGPTGLALFTDPVMTWRDLATSMMTVSDNVAADVILTHI-GL -PRIHADLNQLGLAHTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAASCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAIAVFTMS -ARSELPEVDRAIGEVARSVVT-- ->[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium MJB2 TaxID=2498136 RepID=UPI00101C8AD2 --kTLKNKIENIINSIDGHKGIYIKDCSTNKVI-CINENRIFHAASTIKLPILYDALLQVQ -NKNLTLDDTYHLKASDKVDGSGILKLHIGLEVTLKDLITLMIDVSDNVATNILHDLL-GK -DHINKSIQNLNLKNTFFARKLMICDSN----SHSYTTAKDLGLLLEEFLVCKNLNKDMAN -IGLDILFNQQY-NDRISH------------------------------------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A4P5VGP9_9CYAN ---DLSQEWAKLAAAQGLTASGYLLVLDDGRYA-QLQSDLALPAASSIKIPILLVGLETLD -AGRLRWNDLLPLTSEVRGGGAGWMGNKPGSRFRVYEAATEMIRISDNTATNLMIKRLGGS -VAVNQRFNGLGLKATVINNWLPDLNGT------NTTSSHDLARSIALVDSGEKLSPRARD -LFREIMASSRT-NTLIPAGLLKGISALNKTGDIGI-AYADAALIQLPNGQRAVAAFLVKG -PFND-PRSSELIRAMAAATA--- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus subterraneus TaxID=621109 RepID=UPI000B870082 ----LETGIRTIINKTIDRFSIFIH-TDDGQIA--INAYEPRKAASLIKIPILIEAFRQLE -SDQFRSDTLVYIEQDMKVGGAGVINYLTSSNYSYKNLMELMIIISDNTAANIVLDKV-EM -YQVNALARHLKCEHTEIQRKFMDIASQ-SAGLENYTSAYDMYHFLSTIANSNTISDNSRS -QIVEILSNQQF-GDKLASYLPSDVKLYHKSGELD-GVEHDAAILEYQNKR-IEAVVMSEG -WE-NNGIGKRHIAEIGNLLIDY- ->[subseq from] Serine hydrolase n=1 Tax=Bacteroidetes bacterium TaxID=1898104 RepID=A0A537JYP3_9BACT --sKLQNKIEDAIQGFNGDIGIYIKCLRTGKTV-SINADTVFPTASIVKVPILLGIMDKIQ -KGELAYDSTLVYKDSLLYEGVDILGSFKNDEILLKKVMMLMLTTSDNTASLWLQSLAGKG -TRINEILDSLGLVYTRVNSRTPGRENNRTEYGWGQTTPKEIGTIFEKIYRNEIFSAAACD -RMMRSLGRNYWDLNEAISQIPPYIEVFSKNGCVN-AVRSEVLLVNAPHN-PYIFCIFTKN -NKTHDNEAWTMARKISLMLWRYf ->[subseq from] Beta-lactamase class A n=2 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1I6ZCZ3_SELRU ---SLAQVVESLSNSDSTRYALFVCYPAQDREV-YSYHSAPMRSASMIKVFILGTAMEKIR -DGQLDLYQNLTLHGYDKVGGAGVLAGYANGTLSLDKVMRLMITESDNTATNMLIDLL-GM -ASINEYMQRNGYTDTILQRKMMDSQA-MAAGRENYTSVNDLGNFFVKLYHRSCVSPQLDD -VMLGYLEGQTD-TECFPAALP-GIMICHKTGELY-GLYDDGGIVYQEGN-PFIIVGMTDN -YS-SRGRAISILRQMAQAAAN-- ->[subseq from] Beta-lactamase n=2 Tax=Hymenobacter nivis TaxID=1850093 RepID=A0A502GB41_9BACT -hpALRATIARLAAGAPAKVGVALRVLETNDTL-SYHNRQPYPMMSVFKLAIAMQVLHEVD -RGHLRLAQQQLLTKADLPGHSPLRDKYPSGNVSIQELLTYMVTVSDNNACDILLRLVGGP -AKLTAYVRQLGVWPFVAEVSEAQMAAVWRNQYRNWSYPS--------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=2 Tax=Corynebacteriales TaxID=85007 RepID=A0A2W6RI48_9ACTN -----------------------------EREF-GWAADDPVVMASVYKLPLLLALCDLAE -IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL -PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE -FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA -ARLSLPTVEAAVGRAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sioyaensis TaxID=67364 RepID=A0A4V1NQA4_9ACTN ----TQDHIRTAFADAAVTGWLHACDIDTGAEV-GLHPDHPVVTASVHKLCLLVALHQRAE -QGDFDLTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL -DAVNRTTTQLGLAHTLAVHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA -AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Slackia sp. ZJ119 TaxID=2709798 RepID=UPI0013EC8574 ---DIEASLSQLIEDAGANASFAYRYLSSGWDF-SVHGKESHTAASMISLAVLTQLFDRID -AGDLSLDDEYELTEEAIVGGNGRLQDDPGTAYSLRDLVWYSIVESDNTATNMLIDIA-GM -DAINSEVARQGLEGTKLERHMMDTEAQ-KEGRENRMASDDAAAILNAIAQGAFYNEELSD -FAYDLLSQQKS-DSAVKDALPEGATYAFKSGSLEN-VYNEGGIVFG--EHPYVFVAFVEG -VD--EEEATALVKDAAALV---- ->[subseq from] Serine hydrolase n=1 Tax=Fibrisoma montanum TaxID=2305895 RepID=A0A418MHK9_9BACT ---KLERKLTDLLAGFRGDVGLYVRHLKTGRTV-SLNADTLFPTASTIKIPIQCGLFARLA -TGELAYQQELIYRDSLHYDDGIVGSLKDGARIPLSQVVMLMESVSDNTGSLWCQALAGGG -QAINSWLDANGFRQTRVNSRTPSREANRKQYGWGQTTPRELAELLVYIREGRAVSPDASE -RMYRNLGRQYW-DGDALSQIPPDVQVATKNGAVNQ-SRSEVVLVHAPHGE-YVFCLMTKN -QQDETNEGAMLLRQVSALLWQYf ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces argenteolus TaxID=67274 RepID=A0A561QBZ5_9ACTN ----VERAIRSMFDDAGVRGWLHVADLHHPAQV-TVDPEEQLPIGSIYKVPVMVAFCRLAD -AGLIDPRRRLTLEPDERVPPTGISVLHDAVTMSLRDMVVLMMTISDNASADAVLRAV-GP -DVVDAVCRDLGMPDTHIRGGVVNTFSVYDPAFKASSSPADMARLLRAIWTGQAASDDRCA -FMRKVMRQQPW-THRLGSGFPDAVTVYGKTGTLG-ALRHEAGVVELADGSTYTAVVFTHA -ARSDLPRADAVIGAAARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. CS682 TaxID=1047172 RepID=A0A4P7H2U8_9NOCA --------VQEIFRNVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRAGAADRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI -DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTRLLTLIGEDRAGPAEACR -WVRDLMRQQLN-WHRLAAAFPPEVGVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAIFTRA -GTQRLPAVDRAIGAAAAHAVD-- ->[subseq from] serine hydrolase n=1 Tax=Chitinophaga sp. Cy-1792 TaxID=2608339 RepID=UPI00141FB282 --kKLEAILAPMLKDFHGQVGIYVHHLKKNKIV-AIDADTLFPTASMIKTTIQAGIFNKIA -AGELKYNQELIYKDSLLYAGEDILGSFKNGEIYLDKVLMLMLTMSDNTASLWLQGLAGGG -LTINSWLEANGFKQLRVNSRTPGREVNRKQYGWGQTTPYEMARLMEMIYRGVVIDKNSSE -RMYRNLTRNYWDGQGL-LQVPENVRTASKNGAVDE-SRSEVIMVNAPHGD-YVYCIATKN -NANRDNEAWQLLRRVGYAIWKHy ->[subseq from] Uncharacterized protein n=1 Tax=Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933 TaxID=398512 RepID=A0A0L6JRM9_9FIRM ---KIKSTLLGYLKGVDGHYGVYYYNLFTNESF-GINEYEEFVAASTVKVPINLYLFEKIK -SGDVNLTGTLKYLRNDYEGGTGIIQTSFGKKYTIRQLSKLSITHSDNVATNMLLRFI-GI -GNVKNYMRQIGGTVV--------------NDGKNVSCPRDMGIYMKCVYEFCNNNSDLGK -EFMDNLLNTKF-NDRIPALLPQDIKVAHKIGTQVN-TINDVGIVFTD--RPYIISIMSKE -VDE--NTAPQVVAKISKIVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8LTD7_9BACT ----LDIRIRNEVAPFKGKVFIFAKNLDTGAAY-TFNGDERVRTASTIKIAVMIEVFARVA -EGKAKWTDELVLTKAARFSGSGILPELGDGLLTLQDCVRLMMTLSDNTATNMVLDYLSGT -DSVNDRMNLLGFKATRIMRRVGSGGESKAGKEPGSTTPHEMVQILEKLDRGEVVTQEASK -QMIDLMKREQS-RYAIGRTTP-EIPMASKYGALD-ALRSCVAVLYTKQGR-IAIAITVDE -M---------------------- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429C7B3_9PSEU ------AEIEAVFANAGARGFVHAREVGDGPEV-GVGADDPVVLASVFKIPVAVAFAREVA -AGRLDDTERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRV-GQ -EAVDRVLTDLGLTRTRLIGCCEDLFAVLDPERTTASTAREITTLLDAIWTDRAGDPAACE -RVRAIMAQQIW-PHRISSGFPAGVTIAAKTGTLP-AVRNEAGVVTDVDGRRYAVAVFTRA -ESDRLPAVDSAIGEAAGLAVA-- ->[subseq from] serine hydrolase n=1 Tax=Kribbella sp. NEAU-SW521 TaxID=2185285 RepID=UPI000DD300B5 ------GRIRAIFEDAGVRGWLHATPLDRPHETiEIDSDAVVPLASVYKLPLLVGFCQLVD -QGRLDPREQVTLLPEARTPGPTGLSLLADPIISRRDLAVLMMTVSDNAAADALLDHV-GL -DRLGTILGELGLTRTRIRRGAADNLRVYEAANASSGTARELTRLLSRLWTGDLLSAEQTH -FARTTMERQIF-QHRIAAGFPDGVRVAGKTGTFG-ALRHEAAVVTLPGGDAYAVAVLTLA -ARSDLPRVDAAIGEAARVAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinobacteria TaxID=1760 RepID=UPI0006905774 ----------------------------VEREF-GWAADDPVVMASVYKLPLLLALCDLAE -IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL -PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE -FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA -ARLSLPTVEAAVGRAARIAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Parcubacteria group bacterium 21-54-25 TaxID=1970248 RepID=A0A257TFU1_9BACT ------DKINEILRKADGIWGAAVKPIGNGFLF-EHNANGEFRAASVGKVPIALYLLYLVE -TNGARLEDRFVVSAEYYQPGSGVLSRLTPGVLTLKDLVVLMLTVSDNTAADLLVKAH-GA -DKINNYLTSLGFQKTQLGIKDDDFDF-------GATTPREMAVMLEGIYSARYLNREHSD -LLLQIMKECEN-QLGIKRLLPAKLETANKGGSHDR-LRNDIGIVFTK--QPYVIAIFSKD -LPKPDNPGWLTIARLSAE----- ->[subseq from] Serine hydrolase n=1 Tax=Pararcticibacter tournemirensis TaxID=699437 RepID=A0A5M9H482_9SPHI --kKLTALLQDAAKGFDGTVGIYVQNLKTNKTA-AINADTLFPTASMIKVSILCGVMDKIE -KGELLYNQKLVYRDSLLYPGVDILGSFKDNEIDLSKVAMLMITMSDNTASLWLQKLVSG- -TYINNWLDQNGFKVMRVNSRVEGREPVRKIYGWGVTTPYEMCRLFTLIRNGKVVSPAASE -RIYRNLVRIYW-DEGALSQIPPYVQAASKQGAVD-ASRSETVLVNAPHGD-YVFSVITKN -NKSETNQAHQLIRRISSLLWHYf ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. HB1133 TaxID=2508568 RepID=UPI0014081DCA ----LSQRWVELAQQTDLQASAYMLILDDGRFA-AMQAERPMPAASSIKTPILMAVLELLD -HGTLQWNEPLTLTQELVGGGAGWMASRPLGSFPTYEVATEMIRVSDNSATNLMIARAGGM -EQINARFQALDLPATVVNNWLPDLDGT------NTTSARDLSRAIALVDSGEVLGPRSRD -LFREVMGTSVT-NTLLPTGLMRGYRVYNKTGDIGL-AYADAGLIELPDGRRAIAGFLVKG -PFN-DPRSTELIRQLSAAMA--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Staphylococcus aureus TaxID=1280 RepID=Q2FC28_STAAU ----HAKELNNLEKKYNANIGVYALDTKSGKEV-KFNADKRFAYASTSKAINSAILLEQVP ---YNKLNKKVHINKDDIVAYSPILEKYVGKDITLKELIEASXKYSDNTANNKIINZIGGI -KKIKKRLKKLGDKVTNPVRYE--------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Rhodococcus sp. B7740 TaxID=1564114 RepID=A0A0D5AGS3_9NOCA ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD -EESLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTILRSVWLGTAASPAQCR -YMKDVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A564ULA7_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-HGRTV-EIGADEEFETASTIKAYILAALYLQAS -RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL -DTINACIREMGFAHTVLHNPL---HFDIYSD-LGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A3E2X4L9_9FIRM ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEAFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7Z476_9BACT -------AVAAGSRLCGCRIGVAARHLESGLAY-EHDAGDIFEAASIIKIAVLTEAIAGVR -EGSIDLAERWTLTSPRKASESGWLKLFDPGLPTWNDMLTLMIGPSDNTATNAWIERL-GI -DRINARMESLGFSHIRLLSLLPWLDERWKGLKFGSVTPREVAEWLARVARGELLDAESSH -RMFQYLEASPS-RSRLARRFSSSALWAGKTGTMS-GVRNDSGILRTEKG-RFVLVVLTDG -SSNATHPATVAMGEIARAIVDEw ->[subseq from] Beta-lactamase class A n=2 Tax=Virgibacillus salinus TaxID=553311 RepID=A0A1H0Y7J0_9BACI ----LETGIRTIINKTIDRFSIFIH-TDDGEIA--INAYEPRKAASLIKIPILIEAFRQLE -SDQFRSDTLVYIEQDMKVGGAGVINYLTSSNYSYKNLMELMIIISDNTAANIVLDKV-EM -YQVNALARHLKCEHTEIQRKFMDIASQ-SAGLENYTSAYDMYHFLSTIANSNTISDNSRS -QIVEILSNQQF-GDKLASYLPSDVKLYHKSGELD-GVEHDAAILEYQNKR-IEAVVMSEG -WE-NNGIGKRHIAEIGNLLIDY- ->[subseq from] serine hydrolase n=1 Tax=Terrisporobacter glycolicus TaxID=36841 RepID=UPI00039FC162 ------------LKNMQGDVSFYYKNLTTNNTI-GYNEEKIMLAASVIKLTILVEAFKQIK -EDKIKKEEFFITCEDDKVPSCGALNYMREDLVTLKDLYVLMIILSDNYATNILIDKL-GM -DNINKTIKEIGLKNTVLNRKMFDSEKA-ELGLENYISASDVGYLLEKMYNKDLIDEKSSE -EMISILKNQRL-NGKMPHSLKPKIEIAHKTGEDTN-ITHDVGIVFAK--EPFIVCFCGNN -V--NVPEYERLMQDITYD----- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 311R TaxID=1617904 RepID=UPI00067EA304 ------ASIADVCDDANASVAFHVRSLDGKFEI-GSAADARSVTASTYKVPVMLEVAAQAS -EGRLRLADRIKVPADRRTIPSGISAMTDDVEVSIRDLALLMMQVSDNTATDILQEMV-GT -ESIMRRLRALGLNSTDITTDCDGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA -EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDGDVYLVAIFLRD -KSNNNAKVDAAIGKIAALAID-- ->[subseq from] HGF-1 beta-lactamase n=1 Tax=uncultured organism TaxID=155900 RepID=I0AXX1_9ZZZZ -------DIKEVIQEKKATVGVAILY--QDKIF-TLSDNQQYPLMSLFKFHVTVAALKKMD -REHIPLDSTVYITREQMHEYSPLRNKYPNQGISLRDIITYTIIYSDNNTCDWLIDFAGGI -KKVDTFIKSLGIKKLNLTETEHSMHENIMNSYNNWSSPLSVVQLIKKIYTDEILSATSFA -FLEETMLNCSSGE----------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Senegalia massiliensis TaxID=1720316 RepID=UPI0013620160 --------LESIINEDKLKYSLYVEDLKTNKIIfDINSDAEVTSASMIKIFIMAEAYSQIS -KDEFMSQKIVNIDRDNIVGGSLIKN-LSNYCYSIKDLIFLMMNLSDNTATNQLVDIL-RI -ENINKFINEEGLKNTVINRKMMDFERK-KQGFDNITSASDVAHILKKIYYKDLIDTDASV -NMMNIMKKQMDNRMMARNIDKSNTKIHHKTGNIPY-TNHDAGIVIFKDVE--YLFVMLTW -DGVDNIYGRKVIGEVSEKIYNDf ->[subseq from] Uncharacterized protein n=2 Tax=Synechococcus sp. KORDI-49 TaxID=585423 RepID=A0A076HE25_9SYNE ---ALSQRWTQLAAAQDLEASAFLLVLDDGRYA-QMQADRAMPAASSIKTPILLVSLEQID -RGDLRWNEPLTLTKPVVGGGAGWMAKPLGTRFPTYEVATEMIRISDNTATNLLIQRAGGK -ERLNSRFQALGLTATKVNNWLPDLDGT------NTTSARDLSRAIALVDTGGTLSLRTRD -LFRDVMGTSVT-NTLLPKGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRAMAAAMA--- ->[subseq from] Uncharacterized protein n=1 Tax=Virgibacillus indicus TaxID=2024554 RepID=A0A265NBQ8_9BACI ---QLDKAIQLLVSDVRQNFSIAI-DTPDGH-I-RIDAAKKRKAASLAKIPILIEAIRLAE -ENKLSLEKLIFIEKAAMVGGSGVINYLTDSNHSYQNLLELMIIVSDNTASNLLLDTV-GM -DNINKLAQILNCRETNMERKFMDQQAQ-QEGHENYTSAQDMITFLKLISENDFLSGESRK -QMLRILLNQQF-KNKLAKNLKDQIKIYHKSGELH-GVEHEAAIYNYKNKK-MEVAILSEG -WTRN-GIGQEYIAEIGKLLINYf ->[subseq from] Serine hydrolase n=1 Tax=bacterium (Candidatus Stahlbacteria) CG23_combo_of_CG06-09_8_20_14_all_40_9 TaxID=2014296 RepID=A0A2G9XXJ0_9BACT ---VLQRQIETSVENFHGDVGIYVRHLSKNITA-GINENDLFPTASMIKVPILVKIFDKIE -KGELTIESRVIYYEDSINYGDDAISRFKDGEISIGKLMAHMITFSDNHAGIWLQELAGSG -TAINEWLNQEGFCSTRVNSRTPGREDDYEQYGWGQTTPREMAELLVMIREGRAVSKRASD -DMYRYLTRIYW-DGNALSQIPPTIQVASKQGALDQ-SRSEVLLVNAPHGD-YVFCIITKN -QKDTSNEGSVLIRNVSNLLWNYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_01_FULL_45_11 TaxID=1802070 RepID=A0A1F7JGX3_9BACT ---DLANAITEIIQKEEGEYSVLFSDHKSSDYI-SVNHKSAYTAASVIKIPLLAAIYQLAD -AGEISLDEEITILRSDVQDWGTGTIRYESQPHTVREICQLLIEKSDNTAAYVITNRVIGP -EKIQQIISRWGLSQTNVAE--------------NLTSNQDIEKLMRMMFDGKIADEKLTT -EMISWMDDSDY-ENRLSGLLPESVNVYHKIGNEVR-IIHDVGVIEFDGH-RYYLGILSRE -VP-DLERAERTIGTLSKTVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02460 TaxID=1703941 RepID=A0A1Q5JHB1_9ACTN ----TLTQLRAAFTDAGVNGWMHALDIDSGTEV-DYQGSQLVSTASVHKLPLLIALHERAA -AGDIDLTEQVDCPPDGRASGPTGLAAMADTALSLRDLAYLMMAVSDNASADVILRRV-GL -EAVNRTTARLGLARTHALHSFGAMMAALDPAQSNRSTPRELTQLLATIWRDTACTPDHCA -SMRRLMGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEVGVVQYPDGGRYAIAVFTRT -ASAIVPAADAVIGIAARIAVD-- ->[subseq from] Putative beta-lactamase n=1 Tax=Clostridium chauvoei JF4335 TaxID=1351755 RepID=S6FAK6_9CLOT ------KEIKKYLESRIGTYGFFFEDLKSGFIY-GYNENVKMVAAGCMKLPIAVSLISAVE -HGKVDFMDKIKIDGKDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDII-GM -EQINKDIQEMGLKNTTLNRKTTDE-RKPKNEVENITTASDLSKIWKHLYKGTFLNADNSQ -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIQLSKGN-FAFTIMSMN -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Megasphaera sp. Marseille-P4857 TaxID=2045301 RepID=UPI000C7ACAE2 ----------------AGELAVYCRRLGGEEPF--LLRDRPMAAASLIKIPIMIEAFRQER -AGRISFSARWPVRAA--VPGGSFYTLPINTPVTTAVLIEHMIVESDNTCANMLLDIL-GM -AAVNDCIDGLGLKGTRLRRKMMDFTAA-AAGRENVTTPGDMGRLMTLLAEGRCLGRRADA -AMCGILSRQED-NCVIPAQMARSLRIDHKTGELA-GVYHDCGILYAPQGK-LILCLMADG -IKNEA-QAIYDMSYLARA----- ->[subseq from] Serine hydrolase n=1 Tax=Ruminococcaceae bacterium TaxID=1898205 RepID=A0A348T238_9FIRM ----LERRIDAELCGLDAKMCVYADDL-HGHVV-ERGADDEFESASTIKIYILGCLYAQAE -AGKASLDAELTYEARHFVDGSGLIRSLGEGALRARDVATLMIVVSDNIATNMLIDYL-GL -DTINAFIRSIGCTHTKLHRSLRSDNW---SEKLGTITPRDMGRFFALLAKGELVSPQASD -AMRNVFRQQHY-NTMLAGSIPPYIYVASKSGSMD-ACRNDGGLIHTPYGD-YVLVMMCTD -FANKLEVND-------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces katrae TaxID=68223 RepID=UPI0009974066 -----LHRIRAAFAEAGVTGRLHAVDIDSGTEI-DAGADQPVVTASVHKLCLLVALHEHAA -AGRVDLGEQVECPPGDRTAGPTGLAAMLDPVMSLRDAAYLMTAVSDNAAADLLLARI-GL -DGVNEATARLGLTRTLAVHTFRSLFAALDPAHSNRSTPRDMTRLLAAVWRDEACIPEHGA -AIRRLLGLQVW-PHRMAAGFPDDVHVAGKTGSLPT-LRNEVGVIEYPDGGRYAVAVFTRA -ANATLPAADAVIGTTARMAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED205 TaxID=1986598 RepID=A0A1Z9MLT3_9SYNE ---ALSQRWTQLAAAQDLEASAFLLVLDDGRYA-QMQADRAMPAASSIKTPILLVSLEQID -RGDLRWNEPLTLTKPVVGGGAGWMAKPLGTRFPTYEVATEMIRISDNTATNLLIQRAGGK -ERLNSRFQALGLTATKVNNWLPDLDGT------NTTSARDLSRAIALVDTGGTLSLRTRD -LFRDVMGTSVT-NTLLPKGLMQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRAMAAAMA--- ->[subseq from] Beta-lactamase n=1 Tax=Acidomonas methanolica NBRC 104435 TaxID=1231351 RepID=A0A023D884_ACIMT ----LQDEVARLTEGQPGTFAVYAARLGRAPEV-CLKCDEPINAASTMKLFVLDAAYVAFR -AGTLNPDEMIVVHNRSLVGTRDFSYAEVGKPVSVTELLRVMIQYSSNLATNLMVERL-GV -PFIRSVVAHQGLKGITFGRMIEDFDAD-AQGIRNRVTARGLGDFMQKLAQDRIVDPAASE -AMIAILLGQTF-NNVISPGLPPGTPVAHKTGWVT-GVRNDAAIVFPPDGRTYILVELSRD -LP-DDAAGLKRLNAISAAIYAGf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. IBTA2 TaxID=2283625 RepID=UPI00103DB36B -----ERTIRSLFDDAGVRLHVAELDRPSARVV--LDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPRHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSISDNTAAHAVLRAV-GS -DAVDGMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETALLLRAIWTDEAASPESCA -FMRAAMGTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5K8BQM6_ALCXX --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus erythropolis TaxID=1833 RepID=A0A5N5E563_RHOER ------ASIADVCDDANATVAFHVRSLDGKLEI-GSGADARSVTASTYKVPVMLEVAAQAS -EGRIQLADRIKVPADRRTIPSGISAMTDDVEVSIRDLGLLMMQVSDNTATDILQEMV-GT -ENIMSRLRSLGLNSTDITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA -EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDGDVYVVAIFLKD -KNNHMRKVDAAIGKIAALAI--- ->[subseq from] Beta-lactamase n=1 Tax=Kibdelosporangium sp. MJ126-NF4 TaxID=703222 RepID=A0A0K3BB93_9PSEU -------------RDAGTAGWLHAIQLGTGRQV-DVDADEPVVMASVYKLPLLVALCRQFD -AGRIDPLSTVRINPASCTPPTGISTFLDPITMSWRDLAASMMIVSDSAAADVILGEV-GL -DVVQRTLLELELSGTRIVGGTADVSAAYDPAYTSATTPRDMTRLLALIWSDSVASDEQCA -FIRQLMGKQVW-SHRIRTGFPGDVQVSGKTGTIG-AVRNEVAVVEYSGELPIAVAVFTFA -ARADLPAVDTAIGDAARIAV--- ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Rhodococcus TaxID=192944 RepID=A0A4V3FZ68_9NOCA ------ASIADVCDDANATVAFHVRSLDGKLEI-GSGADARSVTASTYKVPVMLEVAAQAS -EGRIQLADRIKVPADRRTIPSGISAMTDDVEVSIRDLGLLMMQVSDNTATDILQEMV-GT -KNIMSRLRSLGLNSTDITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA -EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDGDVYVVAIFLKD -KNNHMRKVDAAIGKIAALAI--- ->[subseq from] serine hydrolase n=1 Tax=Dyadobacter bucti TaxID=2572203 RepID=UPI001107F45D --eKLTAKIEKALAGFKGEAGVYVRNLKTNRVA-AVYADTLFPTASMIKVPIMCGLFDKIN -QGEIKFGQELVYRDSLKYDNGVVGSFRDSTKIPLPKVIHLMISLSDNTGSLWLQAMAGGG -AAINQWLENNGFANTKVNSRTPGRKQGQATYGWGQTTPREMAELVAMIRDGKAISPSVSE -RMYRYLGMQFW-DGEAISQIPPYVKTAAKSGAVNQ-AKSEVLVVHAPHGD-YVFCITTKN -QQQRENEGYMLIRKISEIIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB02923 TaxID=1718985 RepID=A0A1Q4W470_9ACTN -------RIRAAFADAGVTGRLHARDIDSGTEV-GAGADHPVVTASVHKLCLLVALHRHAA -NGHLDLAEQSECPPGNRTPPTGIAAMLDPVRMSLRDMAYLMMAVSDHAAADLLLERV-GL -DGVNHITRQLGLTRTHATHTFGQLLAALDPARTNRSTPRDMTRLLGAIWRDEACTAEHDA -AIRRLLGLQVW-PHRLASGFPDDVQVAGKTGSLPT-VRNEVGVIEYPDGGRYAVGVFTRA -ASATLPAADAVIGTAARIAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. AmelKG-D3 TaxID=1115568 RepID=A0A1C6MSX9_9ACTN ------RTVRSLFDDAGVRGWLHVAELERSARV-VLDPDEPVPMGSVYKIALMAAFCRLAD -AGRLDPCHRLTLEAADRVAPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLREV-GT -DTVDRMCADLGLPHTRIHGGVVGTYDVYDPAYKASSTPAETARLLRAIWTDRAASPASCA -FMRAAMGTQPW-AHRLASGFPDDVAVHGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia pseudobrasiliensis TaxID=45979 RepID=UPI0009EE3BFE -----------------------ARCLDCGAET-GWRADEPVVLSSVVKVPLVLELARQIA -AGQLDPTDRVRATAADRLGGPGTSGCRDDVEYSLRDAAYLALSVSDNTAADLLFDRV-GL -DNVRSRVHELGLTRTRVVGALRDLLIIMDPGRTSASTPREMTRLLELIARDEAGPPAACA -WLRELMGAQLN-QARLGSAFGDEVTLWSKTGTLP-GVRNEIGVVRSPDGTRCAVAVFTRA -AVDRAPRVDRAIGAAARAAIE-- ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535Y5I6_9CHLR ------------------------------------------------------------- -------------------------------------EVGAMIAVSDNSAANQIVDAI-HP -QAVNDTLARLGLGGTHFMNLFSDARSA-ASPGLNQTTPANMAHLLELIATDQIVSPQVSA -DIRTLLARNVD-RSKLVRLLPPDARVEHKSGWYE-GVANDAGIVTVDRVTRWVIAVFSEN -LP-DAETGNQLVAAISKAVYDAw ->[subseq from] serine hydrolase n=1 Tax=Bacillus mesophilum TaxID=1071718 RepID=UPI00124F3DE7 ---QFNRDVQRLTSAAHGRVSLFIES--DKGVI-EKESHTVYPAASTIKVPILLEALQQAE -SGGIDLKQSISISPSHITGGAGILQSSLPAEMKLVDLLSLMIVVSDNSATNILIDLL-GQ -NQIEQCIKSMNLQETKLQRKMMDFEAG-RRGFENTTSAYDLGICLKFLTEDGLLNEESRA -LGLEIMGRQQL-RKLAYSVSSSEITVYGKTGELP-GVSHDCAILKKDHH-LLYGVVLMDG -IT-QAEEA--------------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_16_37_8 TaxID=1798371 RepID=A0A1F5YVM1_9BACT --eEIKSKIEKELAQAEGTYSIYFYDLTTGDNF-GINDNMMLMAASVNKIPILAASYYFAG -KGVIDLDKIIVPQTKDIQDTGSIRYDKPGTAYSIRTLARLMMEKSDNTAAYLLASVIVGL -DEVQKLVTDWGMLQTDMK--------------ENKTSVKDISKVLKKMYQGEITSPELSR -EMLDFMDDSDY-EDRIPKGVPSTITVYHKTGDEVR-TIHDAGIIVLPDR-PYYLGIMTTD -VA-DAEVTKSKMARISQIVFS-- ->[subseq from] serine hydrolase n=1 Tax=Cytophagales bacterium B6 TaxID=100480 RepID=UPI0003B36DF6 --hKLAVKLQDAVKGFRGQIGIYVQNLKTGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDIQLSKVAMLMITMSDNTASLWLQKLV-GG -QYINNWLEQNGFKVMRVNSRVPGREAIRKIYGWGVTTPREMCRLFTLIREAKAVSAAASE -RMYRNMGRIYW-DEDALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NTTPNNEAGLLIKKVSALLWHYf ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A330LHK3_LACSK -------------------------------SVtNWEPAKSQFSASTIKLFILIRYYQLCQ -SGQLNPDDTYVLQKKDMVQGSGTMNDPVGTKYTLQELCNLMIEQSDNIATNVLIDEVGGF -SAVNRTITSVVKHQSSLERKMMDTS-NIENGRANRINAKEAAQTLLQLYQGKVIDPTTDA -QMLSLMLKTKN-RTKLPSQLPAGAICYNKSGESNRGIENDMALIKYNGH-VFAMCVLIEM -DGEGETPIDATIEQT-------- ->[subseq from] Beta-lactamase class A n=1 Tax=Dethiosulfovibrio salsuginis TaxID=561720 RepID=A0A1X7KZL2_9BACT --------------GIGATAGVVVFAPGLGFRW-SHNDSRRFPAASLIKLAVLWSLFKGDE -AGFWSLQDEMDIPKDHVVEGGLLHRWSHGGRLRLDDLALLMIAVSDNTAANLLIDYI-GM -ERINEDISSLGLRETVLGRKMMDFEAK-KMGMDNYTSPRDLEKLIEALALTG--KPSTRE -RALEMMSCQKL-RSKLPGSIPLEIIVAHKTGELP-GSEHDCGVFFHRGENPVIVVVLTEG -IG-SPEHGVAFCSDIGKKIYVKf ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003A16670 -----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ -ETVDRVLNDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLEAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -HSDRLPAVDASIGAAARLAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudokineococcus lusitanus TaxID=763993 RepID=A0A3N1GA01_9ACTN --------------------------------V-VLGSTESYSSASLIKVALVVAVLRAVD -RGDLALDDTVEVTNSDDVPGTGVLAGYSSPYATIGELCGLAITVSDNTASNVLAEEV-GL -EEVDRLVEDLGLEPTHMGRLFF---SDGPKDESNDLDAASTLELLRAVHDDDVLAPASRG -RLLGWMRQQEL-DTKIAEEVEDDVQTATKTGDTSR-VSHAGGYLLDPGRE-TALVVLTET -EDSPTAAADPYIQDVAALVAE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. ScaeMP-e83 TaxID=1758151 RepID=A0A1C4KHY3_9ACTN -----EAAIRALFDDAGVRGWLHVAELERSARV-VIDPDEQVPMGSVYKVPLMTAFWRLAD -AGRVDPLHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -DVVDGVCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAEIARLLRAIWTDEAASPESCS -FMRAAMGTQPW-THRLASGFPDDVTVSGKTGTFGS-MRHEAGVVELADGSRYTAVVFTQA -ARADLPRADAVIGAVARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=UPI000A3A262D ----LAQIMAETVKNQPGHFAVYAARSGQPPDV-CLNCDDLINAASTIKLFVLDAAYDAFT -KGTLHPEDTLTVHNHSLVGGSFALYAQAGKAVLVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRAIVKAQGLNGVVFGRMIEDFDAN-DQGIRNRVSARGLGAFLQKLDNGQIVGKTQSQ -SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVQ-GVRNDAALVTLPDGKRYILVVLTSG -LP-DEQAGIRVLNTLSHQAYAYf ->[subseq from] hypothetical protein n=1 Tax=Caldanaerobius polysaccharolyticus TaxID=44256 RepID=UPI00068D4A06 --nALKAKLQSYISTRPGQISVYVHDLTTGQTL-SIGGDNVYAAASTIKLPLVLYLYEQAA -AGKIDLNTKLTYTPKYYMQGTGILQGQPFGGYTIRELSRLAIEYSDNVAWQMLLDYA-GQ -DNLTAFEKSLGANATGLVNGLS------------VTTPKDMDIYLSELLAFRDENYDLGN -EVLYYMEHSIF-SEGIPQELPSGVVVAHKMGALDD-KFHDVGIVFG--NRPYIITIFTEN -GWED--ASLQTLADISRIVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A5K8C7B9_ALCXX --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=2 Tax=Williamsia marianensis TaxID=322609 RepID=A0A315S0K9_9NOCA -----SRQMAEVFADAGCAGWVHARTIGRGREF-GWAADDPVVMASVYKLPLLLAMCDLAE -IGQIDLTATVIVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL -PRVQDKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE -FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA -ARLSLPTVEAAVGRAARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis australiensis TaxID=546364 RepID=A0A1K1RJ50_9PSEU ----------EIFAAAGVRGFLHARRLGSEASV-EVGADTPVVLASVVKVPLALEFARQVA -AGLLDPADRVHATAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV -ENVRSLLAELGLSRTSIIGAPRDVLRALDPSRTSSTTPRDMTRLLAAIWA----DPGPGA -RVRGWMAAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGIATYPDGAAYAVAVFTVG -GAETRPDIDRAIGDAARAAVDQ- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_39_10 TaxID=1798375 RepID=A0A1F5ZRR8_9BACT --eTLTKEIKEIIENGGGSYSILAYRYKDGRSI-EINESMQVTAASVNKIPILATLYAMAS -NGEIDIDRQVKLQEDDVQDTGSIRYDPIGTLYSLKTLARLMMEKSDNTAAHILGKIILKE -DKVQEYVDSWGMTQTSMK--------------DNKTSASDMKILLSKIYDGEIANPALSS -EMLDFLHGSDF-EDRIPQDLPTGTKVYHKTGDET-GKIHDVGIVDITDNT-YYIGILTID -MK-DEKKTKKNIAKISQLIYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus sp. 06-469-3-2 TaxID=2022510 RepID=A0A259Y3X1_9NOCA ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD -EGSLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Lacrimispora indolis TaxID=69825 RepID=UPI00045E8AA2 ---TLEKRIEAEVMSYDGKMGIYLDDF-HGNVI-AVHPDEAFETASAIKTYILACLFDEVE -KGNKSLEDMIEYKEEHVVEGSGVLTAEPGARLRVKDAATFMIIVSDNIATNMIIDYL-GL -DTINRCIKALGCRDTVLYNPIH-FER---YDRLGTSTPRDYAGIFTRLAKGELISRTADE -KMLEIFKKQHY-NSMITKDFPPFITVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] serine hydrolase n=1 Tax=Nocardia ninae TaxID=356145 RepID=UPI0011BF8C2C --------VQEIFRDVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRAGALDRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI -DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTRLLTLIGEDRAGSAEACR -WVRDLMRQQLN-WHRLAAAFPPEVGVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRA -GTQRLPEVDRAIGAAAAHAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Echinicola strongylocentroti TaxID=1795355 RepID=A0A2Z4INA7_9BACT ---KLLAGLNVLMEDFEGTAGVYVEHLPSGKFA-AINADTVFPTASIVKIPILVGVFDKIE -KGVLSYHEPLVYRDSLKYGGSGLMQFFDDSTTDLSTLLALMITYSDNTTSLWNQALAGGG -ETINPIMDKYGMEFTRVNSRTQGRKENWEKYGWGQTTPREMATLLKKIRKGEIISPAASE -RMYRLMTNVYY-DDYALSQIPPYIQTAAKQGMVN-ASRSELVMVNAPHGD-YVFYIATKN -NKEPDNASWVLAREVSAFLWQYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces misionensis TaxID=67331 RepID=A0A1H4MGS9_9ACTN ----IEETIAEVFAAGGCRGSLCALEVDGPGRV-SVAGGEPAVAASTFKIAVGLEFFCQAA -QGELDPAERVVVSPAGATPGQGLCITEDPVEISLRDVARLMLTISDNTAADVLIRRV-GI -ERIRARLTGLGLTGFHLPGTIHELDTGMRPGRISSATADDLAALLRVVWRDEAGPAQACA -QLRRTMGQQRL-TRKIAAGFGPEVLVASKSGTVPGGVSNDVGVVAFPDGRRYAVAVLTRS -LTPGAPTREDVLGTAARVALDH- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429F0V6_9PSEU ---RIADEIEAVFAAAGARGLVHAREVGDGPEV-AVGADDPVVLASVFKIPVALAYAREVV -AGRLDETERTRVIARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYRRI-GQ -EAVDRVLADLGLTRTRLIGCCEDLFAVLDPERTTASTPREITALLDAIWTDRAGDPAACE -RVRKIMAQQIW-PHRMSSGFPAGVAVAAKTGTLP-AVRNEAGVVSDVDGRRYAVAVFTRA -ESDRLPAVDASIGTAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013BB5719 ----LSTQIREVAERAGCSLALHVRSLDDDAEV-DIGADTPSLAASTYKVAVLLELACQAA -EGRLDLTGRLRVTPAQHSAISGISTMLDEIEISIRDLALLMIQVSDNTATDVLQRLV-GT -ENIAHRLRNLGIKHTEIRTDCAGLIGESGFRTGNTTTPRDMTRLLQAIWLNQAGPAEACA -EVRRIMSLQFA-PHRISTSYRDGPAIAGKTGTFYGGIRNEVGVLEFGPEDRYAVAVYLRQ -RHYDDGTADAAIGTVTRMAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1G7WDM0_SELRU ---SLAQVVTALSNSDSTQYALFVAYPGENREE-YSYQSKQMRSASMIKVFILGTAMEKVR -DGQLSLYQNLVLHSYDKVGGAGVLAGYASGTLTLDTVMRLMITESDNTATNMMIDLL-GM -EEINAYITRNGYGDTILQRKMMDSQAV-AEGRENYTSVNDLGHFFLKLYHRNCVSPELDD -VMLGYLEAQTD-TECFPAALP-GVMICHKTGELY-GLYDDGGIVYQPGR-HFIIVGMTEN -YS-SRGRAISILRQMAKAAAN-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces qinzhouensis TaxID=2599401 RepID=A0A5B8JA55_9ACTN ----------AAFAGAGVTGWLHARDIDTDAEV-DAGADRPVVTASVHKLCVLVTLHEAAA -AGRLDLTEQTEIPAHGRTPGPTGLGAMLDGALSLRDAAFLMMSVSDNAAADVLLERV-GL -DAVNATTRRLGMPRTEAVETFGSFLGALDPARTNRSTPRDMTALLAAVWRDEAGTPEHCA -AMRRILGLQVW-PHRLASGFPDDVQVAGKTGSVPT-LRNEVGVVAYPDGGRYAVAVFTRA -ASATLPAADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI00142DF7CD ---AVEAEIAEVFADAGARGFLHAREIGGGPSV-AVGADDPVVLASVFKILVAVAYAREAA -AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALVMLTMSDNAATDVVYHRI-GA -AAVDRVPADLGLHRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGDPAACE -RVRSMLARQIW-PHRLSSGFPSDVGVAAKTGTLPS-VRNEAGVVSYPDGRRFAVAVFTRA -NSDRQPAIDAAIGRAGRLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. A23 TaxID=2606593 RepID=UPI0012D74D33 ----------------------HAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETGRTRVGKRYRIGGIGTAGCADDVEMSWRDLALVMLTMSDNAATDVLYHRV-GR -EAVDRVLGDLDLSRTRLIGCCEDLFAVLDPERTSASTPREITTLLDAIWTGRAAEPAACE -RVRSMMARQIW-PHRLSSGFPSDVAVAAKTGTLP-AVRNEAGVVSYPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Gemmatimonadales bacterium TaxID=2448054 RepID=A0A651HSB9_9BACT --tQFQQELEALVSAYEGVGGVHVVDLTDGTRF-AVRDHLIFPQASAIKIPILVELFRQAE -DEPGLRERRVEVTDQVRTAGSGVLQHLTDGGLSLEDHAIYMILYSDNTSTNVLIDEL-GM -DAVNALSASLGAPETRLQRKMIRPEQS-ARGNENLSTPRDAAVIMERIMECDLMSEASCR -RVKEILAIPKGGA--YMDPIPGGVAVPWKPGGIT-GVATAWGAVELPGR-PYVLVVMSSY -GG----DGGAFIRQVSTAAWGYf ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C1JR78_9CHLR ---DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD -DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL -GAVNNLVSCLASHATRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPRGRQ -AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb66 TaxID=1848692 RepID=A0A2S8Z3L2_9MICO ------------------------IGVEGGPEV-SVGADEPVVLASVFKIPVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRV-GA -AAIDRVIADLGLDGTRLIGCCEDLFAAVHPVRTSHSTPRDVTTLLDALWTDAAASAEACR -QARDIMAQQIW-PHRLSSGFPSGVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -TSERQPLVDASIGR--------- ->[subseq from] serine hydrolase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=UPI000995FDF4 ---AARARIAAAFAEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAT -AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLTLAVSDNAAADVLWDEI-GL -DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATSLPTADAAIGTAARLAVD-- ->[subseq from] Putative beta-lactamase n=2 Tax=Rhodococcus erythropolis TaxID=1833 RepID=C3JVV9_RHOER ------ASIADVCDDANATVAFHVRSLDGNLEI-GSGADARSVTASTYKVPVMLEVAAQAS -EGRIQLADRIKVPADRRTIPSGISAMTDDVEVSIRDLALLMMQVSDNTATDILQEMV-GT -ENIMSRLRALGLNSTSITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA -EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDEDLYVVAIFLRD -KNNYNSKVDAAIGKIAALAI--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=A0A4Y3RZJ4_9ACTN -haAARRRITAAFADAGVTGLLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQSS -LGLIDPTRPVEIPAEDRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCAGEYGE -ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAVIGGAARIAVD-- ->[subseq from] Uncharacterized protein n=2 Tax=Fictibacillus aquaticus TaxID=2021314 RepID=A0A235F5M2_9BACI ----FSEYIKEMVSSFNGNASIMIE---GKMNA-EWNSSLRVRSASLIKLAVMLEVFRQAE -QGSLSLTAPIKVSSHCMTGGSGVLKTEVDRTFSILELVTLMITVSDNSATNKLIDLI-GI -NRINSFCKDIGCCETVIQRRMMDLHS----DKDNWTSARDTVTMLKQILRS-----PFQN -EMLSILCSQQF-RHKLPALMNPCLAVGSKTGELP-GLEHDAAIIVKDEGEPVIAAVLLSD -FKNS-NDAIMLHRN--------- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium sp. HMSC073F01 TaxID=1739251 RepID=A0A1E9IK27_9FUSO --eKFEKKLLEILKKYNKKYGIIIKSLESEFFL-KVGNMEAYPAASLIKLPILYELFNNSK ----YNLDEKIEITLKDKVGGFGIIQYHNNVKLSLRDLAILMIILSDNTATNILIDIC-GM -DNINFTLKKLGLKDTKLRRKMMDLKSK-NMGLDNYTSPYDMVKLLEVLNK--------NE -EIISIMKKQLC-NNKISHFIEKKIDFAHKTGDLPQ-IEHDVGIFDIEDKK-IIVVVMTKN -FENR--DEIELNNKVGEFI---- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. 16K104 TaxID=2530375 RepID=A0A4R4XGG7_9ACTN -----NARIRAVFEDAGVRGWLHAVAFDSPSDTvEVDADGVVPMASVYKLPLLAGFCRLVD -LGELDPLERLTLDPSERTAGPTGLSVLADPVMSLRDLAVSMMTVSDNASADALLGLV-GL -RRLADLLESFGLHRTWVRRGTAANLRVYEAANASASTPRDMTLLLRRLWAGELLSAGQTE -FVQATMHRQIF-QHRMASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA -ARGDQPRVDAAIGEAARAAVD-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006BECE9F --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0007614061 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_16_52_11 TaxID=1798374 RepID=A0A1F5YMI2_9BACT ---ELENSIRQAVGNAWKNYSVVVEDMNSSFTV-SIDGMVMHRAASVNKVPILAALYVLSE -RGETDLNRVITLQAGDIQNTGSIRYDSPGSTYSVKTLAKLMIQKSDNTAAYILAQYIVGQ -QRLKKMVSDFGLVQTDMDE--------------NTTSNADMAKLFRKIYRNELTNQAYSG -EMLAFLKDSDF-EDRLPGKLPPGTTIYHKIGTEV-GNIHDVGIVETPDGA-FYIGVLTSD -VT-DETQATELIAMISRLVYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-3213 TaxID=1463846 RepID=UPI000566C571 ----ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA -EGTLDLGAPVTVEPGHPTPPYGLATFRHEVRMSWHDLAILMIGISDNVATDLILAEV-GK -DAVNSTLRRLGFTQTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRGEAAAPEACA -DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -EDSRVPERDALIGFAAATAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A512FIW8_9LACO ----VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH -QNNWQMQNRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV -SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ -AMLTILKANTD-HSKLVKNLPKRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD -GEREA--QTTALN---------- ->[subseq from] serine hydrolase n=1 Tax=Nocardia arthritidis TaxID=228602 RepID=UPI00142D72A1 ----------------GVRGWVHARCLGCGGEV-GVGADELVVLSSVVKLPLVVEFARQVA -AGQVDPRDRVRAEAADRLGGAGTSGCADDVELSLRDAALFALSVSDSTAADLLFDRV-GL -DNVRSLMRELGLVRTRIVGALRDLVLVYDPARTTASTPREMTRLLELIARDEAGPPQACR -MVRELMGHQVN-QQRLPAAFPADVAVWSKTGTLP-GVRNEIGVVEFPDETRYAVAVFTRA -QTLDRPDVDRVIGSAAAAAI--- ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. SP2 TaxID=2268026 RepID=A0A3G3GK38_9BACT --kKLTALLQELIKGHEGDVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIS -KGELKYNAILTYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG -KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELIAMIRAGKAISPDASD -RMYRNLTRQYWDGEGL-SQLPPEIKTACKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN -NKTSNNAGYVLLRKVAKALWNYy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=UPI0011430817 -haAARRRITAAFADAGVTGLLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQSS -LGLIDPTRPVEIPAEDRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCAGEYGE -ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAVIGGAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YUG6_9CHLR ---DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD -DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL -GSVNNLVTSLASRVTRINRYYGKPSMALPDGTHAMATANDLATVYREVLAGKILGPIGRQ -AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Cyanobium usitatum str. Tous TaxID=2116684 RepID=A0A2P7N221_9CYAN ------KRWSELAAQKGLTASAFLLVLDDGRFA-QLQPDLPLPAASSIKTPILLAGLEDLD -NGKLRWNEPLPLTKEVMGGGAGWMAKPVGTRFPFFEAATEMIRVSDNSATNLLIKRLGGK -TTLNERFTAMGLPSTAVNNWLPDLEGT------NTTSSRDLAKSIAMVDIGESLSPRARD -LFREIMGSSRT-NTLIPLGLLQGITVYNKTGDIGI-AYADAALIQLPNGQRAVAAFMVKG -PFND-PRSTDLIRAMAAEV---- ->[subseq from] serine hydrolase n=1 Tax=Legionella tunisiensis TaxID=1034944 RepID=UPI0012EAD828 ------------------------------------------------------------- ---------------------------------------------------------MGGL -EKINDFARSIHNDTFRQDNGWPEAMSGGKNNVYDSSTPKDMAQSLQQLTLNSVLANPQHE -LLLSWLKSNTTGDNRIRAGVPKSWLVGDKTGTGMYGTTNDIGIIWPPQCAPIVMAVYYTN -NNKEAVKREDIVSSVTRLVIDGf ->[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. TaxID=2164130 RepID=A0A4P5VLV2_9CYAN ---ALSQEWARLAAAQGLTASGFLLVLDDGRYA-QLKSDLPMPAASSIKSPILLVGLDELD -RGKVRWNEPLPLTKDVMGEGAGWMANPLGTRFPFFEAATEMIRVSDNSATNLLIKRLGGI -KMVNQRFQELGLPATVLRNWLPDLKGT------NSTSARDLARTIALVDTGEKLSPRARD -LYREILSTSNT-NTLIPMGLLKGITAYNKTGDIGI-AYADAALIQLPNGQRAVAAFLVKG -PFND-PRSAELIRAMAATVS--- ->[subseq from] Zinc-ribbon domain-containing protein n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=A0A4Q9Y0B7_9LACO ----VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH -QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV -SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD -GEREA--QTTALN---------- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C33E8E --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FS--------------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=UPI0003ADD6A5 ----VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH -QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV -SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD -GEREA--QTTALN---------- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329U415_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS -RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL -DTINACIREMGFAHTVLHNPLHDLYN-----DLGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H2ARG2_9ACTN ----VEGELSDAFAAAGVTGFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA -TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -EKINAGMAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPEAACD -EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL -PGPENPAADAVIGTAARIAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermohydrogenium kirishiense TaxID=937254 RepID=A0A4R4A9X7_9FIRM --qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN -VDSDNSDAYTVIRKISKMVYD-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006C435AD --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDAAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Peptidoglycan-binding protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=A0A2G1CJJ8_THETR --qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMEKLLNYANAHSSTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN -VDSDNSDAYTVIRKISKMVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z1V1_9CHLR ---DLNSALEAAISGIQGDFAWHIEDPSTGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD -DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL -GAVNNLVSCLASHATRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPRGRQ -AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPD------------ ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sp. AR-3-6 TaxID=2541721 RepID=A0A4R5E2S6_9BACT --kKLKTKLEKALSGFHGDVGVYVRNIKTNRTA-AVNADSLFPTASMIKVPILCGIFDKIY -KGEVKFDEELIYRDSLKYDNGIVGSFRDSTKIPLPKVVHLMISLSDNTGSLWLQAMAGGG -STINDWLATNGFTNTRVNSRTPGRKQAQATYGWGQTTPREMAELIAMIRNGKAISPDISE -RMYRYLGMQFW-DGEAISQIPPYIKTAAKSGAVNQ-AKSEALIVHAPHGD-YVFCITTKN -QADQENEGYVLIRKVSEIIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429BF30_9ACTN ---RIADEIEAVFAAAGARGFLHAREVGSGPEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYHRV-GQ -EAVDRVLADLGLARTRLIGCCEDLFAVLDPERTTASTPREITALLDAIWTDRAGDPAACE -RVRKTMAQQIW-PHRISSGFPAGVAIAAKTGTLP-AVRNEAGVVSDVDGRRYAVAVFTRA -ESDRLPAVDASIGTAARLAVDH- ->[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1FBL5_9BACT ----LIVQIRNLLVKENGSYSVYLYDLTSNQGY-GINETGIFTAASVNKIPILAAIYFEAE -RGALDLDERITLQQNDIQDYGTGSLDGIGKVYSLKTLAQLMIEKSDNTAAFVLSKIV-GL -KRIQELVENWGLTQTDML--------------ENKTSNKDIAMLMTKMYKNQIANQARTL -EMVGFMDDSDF-ENRLPAQLPEEVVVYHKIGTEV-GNIHDVGIFALANH-PYYLGVMSND -IS-DETRAETVIAEISKLTY--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium GW2011_GWA2_43_14 TaxID=1618443 RepID=A0A0G1FN63_9BACT ----LEKEIAREVAKTQGTFSVYFYDLESGRNF-GINEQMQVMAASVNKIPILAALYYKVA -KNELDLDRIIVPQAKDIRDGTGSIQDPPGTPYSLKTLARLMMEKSDNTAAYILASLVIGL -DDIQSLVESWGMTQTDML--------------SNKTSARDIGIVTIKMYRGEITNSALTR -EMIDFMDDSDF-EDRIPKGVDSQVKVYHKTGDEVR-TVHDAGIIDLPGK-PYFLAVFATD -VV-DATITKEKIVLISRIIYE-- ->[subseq from] Serine hydrolase n=2 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A1Q6QFD9_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS -RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL -DTINACIREMGFAHTVLHNPL---HFDIYND-LGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces diastatochromogenes TaxID=42236 RepID=A0A233S184_9ACTN ----IEDKLAQVFAEAGCQGSVAVLDIDGSGQV-VLDGDELVVAASTFKIAVALELFCQGA -EGELDLAERVRLAPSQATPGQGFCIFEDEAEVSLRDLARMMVTISDNTATDVLIRRV-SV -PRIHARLAALGLDRIRLAGTIQEEFDSLRPGHITSATAGQMAALLRMIWRDEAGPAAACA -AVRSVIGQQRL-TRKIATGFGDEVRVAAKSGTVPGCVSNDAGVVHFPDGSRFAVAVFTRP -TGPQTPQADSVIGTVARLCVEH- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CFH S0261 TaxID=1644109 RepID=UPI00106FB35B -----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ -ETVDRVLNDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLEAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -HSDRLPAVDASIGTAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=A0A6B2DY14_9PSEU ----VETRIADAFLAAGARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVGKRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ -AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTSSTPREITTLLDAIWTDRAGEPAACE -RVRAIMARQIW-PHRISSGFGSDVAIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=[Clostridium] methoxybenzovorans TaxID=81424 RepID=UPI0003F85BF6 ---TLEKRIEAEIMSYDGKMGIYLDDF-HGNVI-AVHPDEAFETASAIKTYILACLFDEVE -KGNKSLEDMIEYKEEHVVEGSGVLTAEPGARLRVKDAATFMIIVSDNIATNMIIDYL-GL -DTINRCIKALGCRDTVLYNPIH-FER---YDRLGTSTPRDYVGIFTRLAKGELISRTADE -KMLEIFKKQHY-NSMITKDFPPFITVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDAAHPATVFGARVSRMILDQf ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum TaxID=1517 RepID=UPI00123B57B1 --qELKNNIETLLSQHPGKYGVYFIDLNSGQTF-NINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMENLLNYANAHSSTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTIMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C2-6-12 TaxID=2698832 RepID=UPI00136CABE1 -------EIKKYLESRIGTYAFFFEDLESGFTF-GYNENVQMTAAGCMKLLIAVSVIKYVE -DGKGSFLDKIKIEEEDKVYGTGILHEFDNREYTLFELLVAMLIQSDNTAANKLIDIV-GI -DNINKDIEAQGLKNTKLNRKTSDERAA-SNGIENITSSLDLAKIWKNLYNSSFLNEKNST -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKN-GVENDTALIHLQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus qingshengii TaxID=334542 RepID=A0A069JTK1_9NOCA ------ASIADVCDDANATVAFHVRSLDGNLEI-GSGADARSVTASTYKVPVMLEVAAQAS -EGRIQLADRIKVPADRRTIPSGISAMTDEVEVSIRDLALLMMQVSDNTATDILQEMV-GT -ENIMSRLRALGLNSTSITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAANAEACA -EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDEDLYVVAIFLRD -KNNYNSKVDAAIGKIAALAI--- ->[subseq from] Uncharacterized protein n=1 Tax=Acidaminococcus intestini TaxID=187327 RepID=C0WAD9_9FIRM --dALQKDVEMYLAKRPGKTAVSCWLLTEKQGF-SIGGKNELPSASLIKLLVLVELCEEVR -RGRANLKEAISILGPAITGGDGIIKEKIGHTFTLEELATLMIIVSDNEAANQLIDRL-GM -KAINERAKKLGLAQTHLGRLMMADAS-GEKERDNWTSADDTVHLLRVICETAKTGSPLGR -WMISLLARQQQ-EGGLRRNLPDFVQVAHKCGNLA-GVEHDAGIFFG--KRPYLLAVLTTE -QPASY-VGRETIG---------- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A6ZBD8_9FIRM ---TLEKRIAAELYCYQGKMSVFLDDL-QGHTV-EVGADEEFETASTIKAFLLAALYLQVQ -RGKADLAEEITYEQSQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DIINACIRELGFAHTVLHNPLHF-DR---YRQLGTTTPRDYAALFVRIAKGELVSREASA -EMLSILRQQHY-NTMLTHDFPQYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A381X8Z7_9ZZZZ ------LRVRNIIRAFSGRVGVSARNLTTSEKF-NINEQTVFPALSSIKLAILIELFYQEK -EGKLQLDEKITITRSDQRGGTGILRDLTPPILSLRDLAVLMITVSDNTSTWLVSSKV-GR -SNVNDRMRLLGLKAMDLRSDLPAIFEHTDIDAYAVSSPADMTDLIGLIAEGKVVSRRACT -QMIEILRMCQS-VDFLGRYLPPEAKLANKIGSMMH-GRTDVGLVETESV-RYVITVMTDR -SLMSVHEGTEVIGRISKAVYDAw ->[subseq from] Beta-lactamase n=2 Tax=Synechococcus sp. GFB01 TaxID=1662190 RepID=A0A0J6BIJ8_9SYNE ---ALSQRWTQLAAQKDLTASAFLLVLDDGRFA-QLKPDLPLPAASSIKTPILLVGLDELD -SGRLRWNEPLSLTKEVVGGGAGWMANRPXGTFPFFEAATEMIRVSDNSATNLLIKRLGGK -QKLNQRFLSLGLSATVVNNWLPDLDGT------NTTSSRDLARSIALVDTGQKLGPRARD -LFREIMGTSRT-NTLIPRGLLQGITVYNKTGDIGI-AYADAGLIQLPNGQRAVAAFMVKG -PFND-PRSTDLIRAMAAEV---- ->[subseq from] Uncharacterized protein n=1 Tax=Acetobacter nitrogenifigens DSM 23921 = LMG 23498 TaxID=1120919 RepID=A0A511XEK3_9PROT ---TLAESISKITAGQPGYFSVYAARSGQSPSA-CLNCDEPINAASTIKLFVLDAAYVAFH -EGALKPDETIIVHNRSLVGTGNFAYAQAGKPVSVAELLRVMIQYSSNLATNLMIERL-GV -MPIRAVVSQQGLDGITFGRMIEDFDAD-RQGIRNRVSARGLGNFLQKLDHGEIVGAPESH -AMIDIMLGQKF-NDIIPPGLPTHTPVAHKTGWVN-GVRNDAAIVFLPSGRHFILVELSRD -LP-NESEGIKVMNRISEVVFAAf ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Microgenomates bacterium TaxID=2093373 RepID=A0A3A4ZMQ0_9BACT ----TETRVQAITKSLSGVYGVYVYDLNAGYAY-GQEEDEVFEAASLIKLPVMAMMYSEAE -NGNLNLNRVYTLKDSDKIGGSGSLYYEPAGTLSLRDLVWKMGQESDNTAFNIARNML-GD -SEIEAYMKNIGMTHTSLKNN--------------ETTPRDMGIFFKKLWEMKLVEEGGRD -EILNSLTGTIY-ENWLPSGLPDSLVVAHKFGREVN-VVNDAGIVFAN--SPYIIVVLSKG -VI--YKEADSALPEISRTVF--- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter denitrificans TaxID=32002 RepID=UPI000743036F --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRVQPSASIIKVPILLALLEAVA -NGRYALEQSLALPASDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora halotolerans TaxID=1981512 RepID=UPI0013D0E8E4 -----ERKIQQCFDDAGGHLHAVALH-DRHREI-GVLPDEPVVLASVFKLPLMIAFAQMVD -AGELDPTELTTLTPDVRSPPTGFAAMADPVTVSWRDIARSMMTVSDNTAADALLSVV-GL -ERVRTALAGLGARSTRVVGGIRDLYDDPANPHNNVGTCRDMLLLLEAVWQDRAASAEQCA -FIRGVMAQQVW-TQRLSAGFPDDVVVSGKTGTFV-ALRHEAGVVEYPNGESYAVAVFTLS -TRLVLPAADAAIAQAARLAVA-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-128772 TaxID=2073159 RepID=UPI000CD15747 ---------------VGVRGFLHARRLGSSGET-GLDADEPVVLASVVKVPLAFEFARQMA -AGLLDPADRVRATAADRLGGTGSAGFADDAEYSLRDAARLALSVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTSVMGAPRDVLRALDPLRTSATTPREMTTLLAAIWAADAAAP---- --VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGTAYAVAVFTTG -GAETRPDIDRAIGEAARTAVDQ- ->[subseq from] Beta-lactamase n=1 Tax=Acidaminococcus intestini (strain RyC-MR95) TaxID=568816 RepID=G4Q913_ACIIR --dALQKDVEMYLAKRPGKTAVSCWLLTEKQGF-SIGGKNELPSASLIKLLVLVELCEEVR -RGRANLKEAISILGPAITGGDGIIKEKIGHTFTLEELATLMIIVSDNEAANQLIDRL-GM -KAINERAKKLGLAQTHLGRLMMADAS-GEKERDNWTSADDTVHLLRVICETAKTGSPLGR -WMISLLARQQQ-EGGLRRNLPDFVQVAHKCGNLA-GVEHDAGIFFG--KRPYLLAVLTTE -QPASY-VGRETIG---------- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. NEAU-Ht49 TaxID=2483351 RepID=A0A3M2LTS5_9ACTN ------AAIERAFADAGVAGHLHAVDVDTGREL-GVGADEPVVLASVYKVPLLVAFFRLAA -RGALDPAERITLCPAERTEGTGLSVMLDDVTMSLRDLACLMITVSDNAAADAVYARV-GR -DEIGAALGALGLTRVHVTGDGRDLFASLDPSRTSDGTPRELTRLLSMIWRDEAAPAPECA -QMRRLLGLQVW-PHRLSSGFPDDVRVSGKTGTLLT-VRNEIGVVEYPDGGRYAVAVFTRA -AEAVAPRADAVIGTAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. ND2010 TaxID=1410618 RepID=UPI00068C90BA ---ELNRNIERILGGDSARYAIYFLRPAEEEEP-FLYQNRPMSPASMIKVFIMAAVMQEVH -DGRLSLEEKLVIRESDVVGGAGVITWNIGEVRSIRELVSGMIMSSDNTATNILIDRL-GM -DKINRYIQEHGYGDTQLVHKMMIGN----GGRKNFSSARDLGKLFSRLYYHQLVGESEDR -FMELVLSGQKD-KECFNAALP-DFTIAHKTGEVT-GLYDDGGIFYGKQGD-FVLVIMNEG -FT--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis vancoresmycina DSM 44592 TaxID=1292037 RepID=R1I0L2_9PSEU ----------AFFEAVGVRGFLHARRLGTADSL-GLAADSPVVLASVVKVPLAYEFARQVA -AGQLDPADRVHASAADRLGGTGSAGFADDVSYSLRDAALLALTVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTTVVGAPRDLLRALDPLRTSATTPREMTTLLSAIWADDVGAP---- --VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGAAYAVAVFTAG -GAETRPDIDRAIGAAARAAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPLOWO2_01_FULL_46_9 TaxID=1798394 RepID=A0A1F6AXP2_9BACT ----LQDKIKQRIGNAWDNYSILVIDYNSPFVL-GINESTIYAAASINKVPILAAIYDKAQ -RGQVDFDKVITVQKEDIQDTGSIRYDPPGSTYSIKTLVRLMMQKSDNTAAFLLANYIIGL -SAVQSYINQNGLTQTDMV--------------KNKTSNKDMAILFEKIYRRKITNPALSD -EMLGFMADSDF-EDRLPGLLPKGTKVFHKIGTGT-GAVHDVGVVEHGKT-VYYIGMFTSD -VG-DEEQAAKLVAEVSREIFD-- ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. TaxID=1411316 RepID=A0A520ACT8_9SPHI --kSLQKKLNELVQGFNGDVGIYVKNLKTGKTA-SINADTIFPTASMIKVPITCGIFNKIE -KGELDYHSELMYCDSLLYAGEDILGSFKDSEIALNKVLMLMITTSDNTASLWAQLLAGTG -TSINDVMASNCLKDTRVNSRTPGRKDNQRKYGWGQTTPKEMATLLTLIRDGKMINPAASE -RIYRNLIRIFW-DTEALSQIPPTIQVASKSGAVD-AARSEVLLVNAPHGD-YVFCITTKN -QKDTSNEGWTMIRKLSNLLWNHy ->[subseq from] serine hydrolase n=1 Tax=Mycobacterium haemophilum TaxID=29311 RepID=UPI000655C155 ---EVSRQIQAVFTDAGCRGWLQARPVSTVEPAiNFRADEPVPTASIYKVLLLAAVARSFD -RGELDPSARVTIRPTDCTPGPTGFSTFIDPVVSWRDLARSMIVLSDNAAADILLAAV-GL -PRMDEIIDELGLASTRVIGGAAALYEIYDPDQTNATSAADSNTILAAIWTDTIASPHACS -YMRGVLAQQVW-PHRIKSGFPREISVAGKTGTIGK-IRSEVAVISLPNETPIAVSVFTHA -ARHSLPAVDRAIGTAARIAVT-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. WAC 06738 TaxID=2203210 RepID=UPI0013E0C96D -------------AEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTAAVEVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAGRLAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Williamsia muralis TaxID=85044 RepID=A0A495K719_9NOCA -------QMTEVFADAGCAGWVHARTIGRGREF-GWAADDPVVMASVYKLPLLLAMCDLAE -IGQIDLTATVIVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL -PRVQDKLDALGLTETRVVGGMAELQQAYDPALASATTPRDATRLLQLIWTDQAVSAQMSE -FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA -ARLSLPTVEAAVGRAARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561W957_9ACTN ----------------------------AFREV-GVRADEQVVIASVFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCVDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRIRGGPRELVEVFDPAHTTSSTAREITRLLSMIWRDEAGPAGACA -MVRTWMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DQSRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. An122 TaxID=1965551 RepID=A0A1Y4T4V0_9FIRM ---TLEKRIAAELYSYHGQMSVFVDDL-QGHTV-EMGADEPFETASTIKAYILAALYLQAS -RGKASLEDTVTYRPEHFVDGSGMLRAGVGAALKVKDAATMMIICSDNIATNMIIDYL-GL -EEINRCIQELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAGLFARVARGTLVSREASA -DMLAIFRAQHY-NTMLTGNFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN -FDD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. QMT-28 TaxID=2662397 RepID=A0A5Q0L9Z3_9ACTN -------------------PGTAGLTEPRAREV-AVGADEPVVLASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNSAADLLLDRV-GL -DTVRLLTQELGLTRTRVVGGPRDALEVLDPLRTNAGTPRETTELLRLIWRDEAASPEACA -QVRDLMSRQVF-RHRLASGFPGDTVIAAKTGTLP-GLHMEAGVVGYPDGRCYAVSVFART -REVTGPEVDAAIGAAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CNT371 TaxID=1136433 RepID=UPI0004AE39FE -hrTARSRIRRAFAEAGVTGQLHARDIDTGAGL-AVAADTPVSTASVHKVCLLAALYREAE -HGRVDLTAAVDIPADGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAVLDPARTNRSTPRELTALLAAVWRDEVCTGVYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas sp. AE3005 TaxID=1485543 RepID=UPI00068C574D ----LAQNTQSILGTESKGFSVYFLRPEREVEP-YIHNQRAMMPASMIKLFVMAKVMQDVH -DKRLFLDEQLTIKRKDVVGGAGVITWYNAGERTILQLVKLMITDSDNTATNMLIDRV-GL -TQLNAYLSQQGFKDTVIANKMMTGNRG----RKNFSSVRDIGHLLTRMYYRELVAEEEDS -IMLDILLEQND-KECFPKALP-AYKIAHKTGEID-GVFADGGIFFGPQGTFILVAI---- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. B7740 TaxID=1564114 RepID=UPI0009E197A8 ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD -EESLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTILRSVWLGTAASPAQCR -YMKDVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536LW71_9CHLR ----LEGELLRIGSTYSGKWTYALTDMSSGQKI-GHRQDDVMPTASLIKVPVLTALYRAVH -EGRLRLTDRIRYGDEHRCLGSGVLSRLTPGVMTVRDAAVLMIIISDNSATNFVIDLV-GL -DQVNETMRCFGLGRTTIFQRLGDTKAGLDARKMSVSTAGEMTRLLELIARHEAVPPEASE -DMLRIMRRQDY-RHELSRLLPTENWVAEKGGSFLNGIRTSGAIFNGSRG-KFVMSVFCEG -GTGP------------------- ->[subseq from] Serine hydrolase n=1 Tax=Subdoligranulum sp. APC924/74 TaxID=2086273 RepID=A0A367GEB4_9FIRM ----LERRIDAELCGLDAKMCVYADDL-HGHVV-ERGADDEFESASTIKIYILGCLYAQAE -AGKASLDAELTYEARHFVDGSGLIRSLGEGALRARDVATLMIVVSDNIATNMLIDYL-GS -DTINAFIRSIGCTHTKLHRSLRSDNW---SEKLGTITPRDMGRFFALLAKGELVSPQASD -AMRNVFRQQHY-NTMLAGSIPPYIYVASKSGSMD-ACRNDGGLIHTPYGD-YVLVMMCTD -FANKLEVND-------------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus massiliogorillae TaxID=1243664 RepID=UPI0003A49224 ---NIHKILQQQLQQYQGNFAYVISH--DSSKI-EHNSSVITSSASTIKIPLLIEALRQCE -EGRLHLGMMISIPKRDIVGGAGVLQSLVVTSLSLRDLLALMIIVSDNTATNLVIDVL-GL -EQIKNGYKRIGLHSTSVQRKMMDFES-LKNGKDNLISAEDLHKCLLIINEPSILRKDSQK -VMHEMLEKQQF-REKLPYYMDESMWIGNKTGELP-GVEHDCAIIKYGPHT-VYAVILCSD -LE-QQQDGKQLIRVVGQTINE-- ->[subseq from] serine hydrolase n=1 Tax=Arsenicicoccus sp. MKL-02 TaxID=2663847 RepID=UPI0012B5402B ---VLQRDLKDIVRHAPGRLSIQVVG-PEGVLA-GWDSNRGVPAASLVKVLVLVATLREVE -AGRLSLDQTLRIP-DDRVGGAGALSLLPSVVLSVVELLRLMVTLSDNDAANLLLRLL-GH -DRVTRCGLELGLRHTHVRRDLMDSRSA-SQGRDNTTTAADQAGLLAVLRAGQALGAQQTA -LALALLSEQQH-AYGVTALLPDDVVRGSKPGDLP-GIRHDVALIETG-GAWAAVAVTATG -MYDDR------------------ ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000B419B04 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAELTKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Desnuesiella massiliensis TaxID=1650662 RepID=UPI0006E37309 ------KEIKRYLESRIGQYSFYFEDLDGGYIY-GFNENVKMTSAGCMKLPVAMALFKEIE -NNKISLDTKLSICGDDKVFGTGIIHEFCERDYTVLELVIAMLIQSDNTAANKIIDVL-GI -ERINEIIKDMGLSNTELNRKTMDEK-NVRDVVENLTSSFDLCKCWKHLYKHTYLSEEHSN -KLIDILRRQQL-KNKVAFYIPENFTIASKSGDLE-GIENDTSIIQIPKGN-FAFTVMSKG -VP-NNVYGNVTVAKCGKMVWD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium baratii TaxID=1561 RepID=UPI00097FAC8A ------KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE -LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM -ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMIWKILYDATFLSKENST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Mycolicibacterium sp. P1-18 TaxID=2024615 RepID=A0A5A7XZ13_9MYCO ---DVTARISEVFADAGATLHAVAADGSSADDV-DVDGDRPVAIASVYKLPLLVAMMRMVD -GGRLDPTEAVTLRPDDRTVPTGISTLSDAVTMSWRDLAAMMMAVSDNAAADAILRRV-GI -DDVAETLRALGLPRSRIVGGTADAYRAYDPVHSSSATARDMTTLLTSIWTDRAATPPSCA -VIRTLMSRQVR-NARIASGFATGVRIAGKTGTLG-ALRHEVGVVQFDDERPYAVAVFTQS -ARAAQPRVDAAVGYAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=UPI000995E951 ----IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPGHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRMASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Fibrisoma limi BUZ 3 TaxID=1185876 RepID=I2GP14_9BACT ---KLERKLASLLDGFQGDVGLYVRHLRTGRTV-AINADTLFPTASTIKIPIQCGLFAKLA -AGELTYQQELIYRDSLHYDDGIVGSLKDGAKIPLSQVVMLMETISDNTGSLWCQALAGGG -QTINTWLDANGFRQTRVNSRTPGREAYRKLYGWGQTTPRELAELLVYIREGRAISPDASE -RMYRNLSRQYW-DGDALSQIPPDVKVATKNGAVNQ-SRSEVVLVHAPHGE-YVFCLMTKN -QKDESNEGATLLRHVSALIWQHf ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A291TA60_9FIRM ---TLEKRIAAELYSYQGRMSVFVDDL-RGNTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Oceanobacillus sp. E9 TaxID=1742575 RepID=A0A1E5K5C3_9BACI --------------------------T-KDGDI-GIEEEKVYSSASTIKVPILMEALLQGE -QGIINLDEKITVSDSDITSGGGIIRHMSANQLSLRDLLYLMITQSDNTATNMIIERV-GM -DSVNQTIAEMGAEDTILQRYMMESVR--PN--DNLTSAKDMATIMQSAFESDILSSENKE -EFLRIMGEGIL--SHYRSDRHKDISNYSKGGSLGTNVRHNIGMFTYQDE-VVYVSVMSED -AE--LKSSRIVMAEIGERVMDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Hungateiclostridium clariflavum (strain DSM 19732 / NBRC 101661 / EBR45) TaxID=720554 RepID=G8LU97_HUNCD --eNLKNELEEYVSRFTGQYGIYFVDLVSGYEF-GINDTDEYTAASTIKVPLNYYIFKMIE -AGEVDPEDTIAYKEDDFEGGTGILQSKKLKGFTIRYLLKVSIIYSDNIATNMLLRHF-GR -KNFKNYLRMLGGTVV--------------DDNKNVSCPKDMAIYLKNIYEFCNENKELGK -ELKYNLCNTIH-NDRLPRLLPKDVKVAHKIGDQIQ-AVHDVGIIYADN--PYILAVMSKG -VI-SDEEARSVIAQVSKKVYD-- ->[subseq from] serine hydrolase n=1 Tax=Hungateiclostridium clariflavum TaxID=288965 RepID=UPI000487EA7B --eNLKNELEEYVSRFTGQYGIYFVDLVSGYEF-GINDTDEYTAASTIKVPLNYYIFKMIE -AGEVDPEDTIAYKEDDFEGGTGILQSKKLKGFTIRYLLKVSIIYSDNIATNMLLRHF-GR -KNFKNYLRMLGGTVV--------------DDNKNVSCPKDMAIYLKNIYEFCNENKELGK -ELKYNLCNTIH-NDRLPRLLPKDVKVAHKIGDQIQ-AVHDVGIIYADN--PYILAVMSKG -VI-SDEEARSVIAQVSKKVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Subtercola boreus TaxID=120213 RepID=A0A3E0VSH6_9MICO ------------------------------------------------------------- ---------------------------------------------------------MGGP -AALDAALRDQGDDVSEAVNSEPALNVIEPGSTDDTSTPAAFTANLSRLIAGSYLAMDDRM -LLLEWMTGNATGDTLIRAGAPSGWNVADKSGGAG-GIRNDIAVVTPPGGHPIVLTIFTNT -LDPDAAYDDALVADVARAVL--- ->[subseq from] serine hydrolase n=1 Tax=Paracnuella aquatica TaxID=2268757 RepID=UPI000DEFDB4B -hkKLQQAIEQMAVGFGGQVGIYVKDLRSGRMA-AYNADTIFPTASIVKIPIAVGIMQKLE -RGELTYHQPLVYKDSLLYPGVDILGSFKNGEIDLSKVLMLMLTTSDNTASLWLQSLAGGG -TTVNVLMDTLGFPQLGVNSRTPSREADREVYGWGQMTPRAIAGLMEEIYRRRVISPAASD -RLLRLLNRNYWDAEALSEIAP-YAAVFSKNGAVNE-SRSEVVLVRGKKSA-YLFCIATKN -NRTPDNEAWTLTRKLSAYLWQHf ->[subseq from] Serine hydrolase n=1 Tax=Deltaproteobacteria bacterium TaxID=2026735 RepID=A0A534PPZ1_9DELT ------------AAHAAQTIAISFHDLQTGQRV-ELAAGERMHAASTMKLAVLLAAHR-L- ---ELDLDQPVRVENKSLADGSDFSYTQLGREVPLRVLLERMIIRSSNLATNLVLQRL-DA -ARITQVCRELGARDIEVLRGVEDGKA-FAKGLNNTTTAHDLAVLLEAS--------AAQP -EIVELLARQEF-NEGIPAALPKGTRVAHKTGDIDR-IYHDAALVYPPGRKPYVLVVMTRG -FA-TLEQGAAAVREVSRAVWQ-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces venezuelae TaxID=54571 RepID=UPI000BFF755E -haAARRRITAAFADAGVTGQLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQAS -LGLVDPTRPVEIPAIPAEGGATGLSMRDAARLSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCPGEYGE -ELRALLGLQAW-NHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAVIGGAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012AF4D24 ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-QIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium septicum TaxID=1504 RepID=A0A386PH62_CLOSE ------KEIKKYLESRIGTYGFFFEDLKSGFIY-GYNENVQMIAAGCMKLPIAVSLISAVE -QGKVDFMDKIKIDGKDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM -EQINKDIQKMGLKNTFLNRKTTDE-RKPKNEVENITTASDLSKIWKHLYEGTFLNADNSQ -MLVDILRRQQI-KNKSALYIPDDYEISSKTGDKS-GVENDTALIQLSKGN-FVFTILSMS -IPN-SVYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase 3 n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A564T657_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS -RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL -DTINACIREMGFAHTVLHNPL---HFDIYSD-LGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Amycolatopsis mediterranei TaxID=33910 RepID=G0G3W8_AMYMS ---------------VGVRGFLHAHRLGSSREC-GLDADSPVVMASVVKVPLAFEFARQVA -AGQLDPTDRVRASAADRLGGTGSAAFADDAEYSLRDAALLALSVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTTVIGAPRDVLRALDPLRTSATTPREMTTLLAAIWADDVGAP---- --VREWMSVQ-VGWHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGTAYAVAVFTTG -GAETRPDIDRAIGAAARAAVDQ- ->[subseq from] Serine hydrolase n=1 Tax=Planomicrobium sp. CPCC 101079 TaxID=2599618 RepID=A0A5C5SV28_9BACL ------KKIEERLLNVDSNYSMFIE--TEGQSI-SINPDKKMRAASVIKLPILIEGYRQID -NGEINAKVGIVWSEKDLVGGSGVLADLTSVHLSLPDILMLMTIVSDNTASNLAIKHL-SI -EKINRLSEVLGCTNTILGRQFMDFEAA-EKGLDNYTSARDMVLFLKEAETGKILSEESKQ -QVKHALSQQQF-VANLHGRFDSEVIIASKSGSLE-GVVNDVGIFEYRGMK-VYAAVLLDN -LP-DNHTGQEIIADIGWYVYEY- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces hygroscopicus TaxID=1912 RepID=A0A1S6RQ16_STRHY ----IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPGHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRMASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonas sp. SG8_23 TaxID=1703356 RepID=A0A0S7YUG0_9BACT ---DLEARVTARLDALDAVSSLYARHLPSGREI-AVRADRPMNTLSVIKIPVMVQAFLDDR -SGRLDLDARRTVRPEDLRRGSGLLQTFAPGLPTLRGLVTQMIITSDNTATDMVIDAV-EL -DRVNALLEREGYRETRLRMTTGDLFRRFEGDSTGRTTAREMGRLLQQILEADLADREASD -EMIGMLRSQFY-TSRLPQRVRQDVGVAHKTGDWPPIAGNDVGILFYEGG-PAIVSVFTNQ -NRGDFFELEATLGLIAEDVVTAw ->[subseq from] Serine hydrolase n=1 Tax=Clostridium indicum TaxID=759821 RepID=A0A3E2NA34_9CLOT ---TLEKRIQAEIMSYDGKMGIYLNDF-HGNEF-ALGQEEKYETASTIKTFILASLFDEVE -KGNKSLEDFVEYKKEHVVDGSGVLVSLEPGALRIKDAAVFMIIVSDNIATNMIIDYL-GL -DTINRCIEKLGCKDTVLYNPIHFDQY----RRLGTSTPKDYGSVFTRLVKGELVSPQADA -AMIEILKKQHY-NSMITKDFPPVITVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE -FSDAAHPATVFGARVSRLVLDQf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=A0A1U9R4A5_STRNV ---------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQAA -AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GR -DTVQALARQLGLERAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA -GVRELMSLQVN-GARLGAAFDRFTTVAAKSGTLP-GVRNEIGVVTYPDGARYAIAVFTRT -TSTRRPDLDTAIGGAGREVVE-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006681122 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRAGLAASRLQRLMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPSPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia ninae NBRC 108245 TaxID=1210091 RepID=A0A511MGK3_9NOCA ---------QEIFRDVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRAGALDRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI -DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTRLLTLIGEDRAGSAEACR -WVRDLMRQQLN-WHRLAAAFPPEVGVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRA -GTQRLPEVDRAIGAAAAHAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2500 TaxID=2512214 RepID=A0A4R2CJY9_9ACTN -----NARIRAVFDDAGARGWLHAISLDRPEDSvELDADVVVPIASVYKLPLLAGFCRLVD -AGELDPCEQLTLSPESRIPGPTGLSILADPVMSLRDLAVTMMSVSDNASADALLNKV-GP -GRLAELLQSVGLEHTRVRRGAAGLVEVYDAANLSAGSARDMTLLLREVWGGRLLSEGQTA -FVRRAMEQQVF-TQRIAAGFPDGVRIAGKTGTFG-ALRHEVAVVTLPGGDAYAVAVFTHA -ARGDLPRVDAAIGEAARLAVDH- ->[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Selenomonas sp. CM52 TaxID=936381 RepID=J6HU85_9FIRM --eALRADFSAILAQKSPDCSVFLLRPREEKEP-LLYQSHAMQPASMIKLFILAYAMQQAK -DGTISLAEPLSITEANIVGGAGQLNWYDRGKLTIEQLLERMITDSDNTATNILIDRL-GI -ENIDGYIRQKGYADTCLQHKMMLSNQG----RPNLSSVKDIGTLLSLIYRGECVDYEHDK -KMLQILSRQKD-KDCLPSALP-AFLVANKTGEIT-GVYADGGIAWSDAGD-LILVVMDEN -CR-DRQETIALFQRIAQRA---- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BEF828 --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAAERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWNQRAGLPASRLQRRMMDAAA-REAGRDNFTSAEDATASLCWMLRDGALPAALRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=A0A562WHB8_9ACTN ---------------VGVDARLHAVDVDTGHEI-GVGADEQVVIASVFKILLVLEFARQAA -DGQLDPTERVVVRAEDRLGGWGTAGCADDVELSLRDLAYFAMSVSDNTAADLLMRRV-GP -DLLPLLATELGLTRTRVIGGPRQLLEVFDPDRTTSSTAREITRLLTLIWRDEAGPPAACA -MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHMEAGVVRYPDGGRYAIAVFAQT -RRTRRIDVDLAMGEAARMAVE-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia suismassiliense TaxID=2077092 RepID=UPI000D1DBB3D ---------QEIFRDVGVQGWVHARCFDCGAEV-GSGADEPVVLASVVKVPLVLEFARQVA -AGQLDPTDRVRAGAVDRLGGVGTAGCHDDVDLSLRDAAFFAITLSDNTAADLLFERV-GI -DNVRSLVRELGLAGTRIVGAPRHIVQALDPQRTTASTPREMTQLLTLIGEDRAGPAEACR -WVRDLMRQQLN-WHRLAAAFPPEVQVWGKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRA -GTQRLPEVDRAIGAAAAHA---- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. SN20 TaxID=1776383 RepID=UPI000C7822D2 ---ELDAWLREQIDAFPGKVSLLMTDLINGKHYhSFDPDTQVVSASTIKVPILLYALEQVR -QKRLSLEQAVPVPAESILPDTEVFELCLP-EYSLWELLYWMIVESDNTATNLVLDLL-NW -DEMNAYFKDLGLKHTVCQRKMLDWDA-VAAGKNNYTSAADQERIYWALYRGTILTHDLQE -KALDMLRRQRC-NDSFLRYIPQPVVVAHKTGGLDH-VNHDAGIFELFSH-PFYLGIFTWD -GPDGQPDQKRFIGKLAKQIYEIy ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. An192 TaxID=1965581 RepID=A0A1Y4JAY3_9FIRM ---TLEKRIAAELYSYHGQMSVFVDDL-QGHTV-EMGADESFETASTIKAYILAALYLQAS -RGKASLEDTVTYRPEHFVDGSGMLRAGVGAALKVKDAATMMIICSDNIATNMIIDYL-GL -EEINRCIQELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAGLFARVARGTLVSREASA -DMLAIFRAQHY-NTMLTGNFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN -FDD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus kimchii TaxID=746691 RepID=UPI000A06F2ED --------------------------T-KDGDI-GIEEEKVYSSASTIKVPILMEALLQGE -QGIINLDEKITVSDSDITSGGGIIRHMSANQLSLRDLLYLMITQSDNTATNMIIERV-GM -DSVNQTIAEMGAEDTILQRYMMESVR--PN--DNLTSAKDMATIMQSAFESDILSSENKE -EFLRIMGEGIL--SHYRSDRHKDISNYSKGGSLGTNVRHNIGMFTYQDE-VVYVSVMSED -AE--LKSSRIVMAEIGERVMDY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. L-9-10 TaxID=1478131 RepID=UPI00101DBE4D -----------------------------RAEV-AIGADEPVVLASVFKVLLVLEFARQVA -AGQLDPRERVWVTADDRLGGWGTAGCLDDIGVSLRDLAHFAMSVSDNSAADLLLARV-GT -DTVRLLAEELGLHRTRILGGPRQLLEVLDPERTSASTPREITRLLELIWRDEAGPPEACA -QVRELMGRQVF-RHRLVSGFPDEVRVAAKTGTLP-GLHAEAGVVHYPDGGRYAVAVFART -GDTNRTAVDSAIGAAARIAVE-- ->[subseq from] hypothetical protein n=1 Tax=Streptococcus suis TaxID=1307 RepID=UPI00041ED443 ----------NIFGAIGGDKSFYVKSTS-GTEF-IHINDRVQRSASTIKLFILAAAYNKAH -RGELNLGAPYTVQASDIVKASTSLANAAGRTYTIGQIARFMVETSDNTATNIIIRKIGGV -SAVNAEIRKLGYTKTTLERFMHDPV-AIAAGLENYISAQEAADLITNILNKTLISAGADG -QMINDLSNNFY-ADWLTASIKQYALVFDKPGSHGYGVENDIAIITRNGQ-SVAVALLTQH -TGSNGR----------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Bauldia litoralis TaxID=665467 RepID=A0A1G6BWH2_9RHIZ ---VLEHRLTHLADSLRADWGIFVHFVNGGGEI-AINADRQQDTMSLIKVALLVTLMRKVE -TGEVDLATRVTLGDDDKRLGTGVLFLFDAGAFTLKDAAWLMIVISDNSATDIVLDAVGGP -EAVNQTMAALGLDQITMTGNALAWFRFGEDRPFALATARSLGLLMLQIHDHRCASPESCE -TMLAMLRGQQL-HSMLPKYMW-GVTAAHKTGNFPPFISSDLGIFTPAAGSPVIISIMTQQ -HRGQRALVEDTVARMGELIIH-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Amycolatopsis TaxID=2618356 RepID=UPI00106E7521 -----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ -ETVDRVLNDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTERAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -HSDRLPAVDASIGAAARLAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium saccharolyticum (strain ATCC 35040 / DSM 2544 / NRCC 2533 / WM1) TaxID=610130 RepID=D9R4T6_CLOSW ---TLEKRIEAEIMSYDGTMGIYLDDF-HGNVI-SVHADETFETASAIKTYILACLFDEVE -KGNKSLEDMIQYREEHVVDGSGVLGALEPGALRVKDAATFMIIVSDNIATNMIIDYL-GM -DTINRCIKALGFKDTVLYNPIHDIY-----RRLGTSTPRDYAGFFTRLAKGELISPKADG -KMLEIFKKQHY-NSMITKDFPPFITVASKSGSMD-ACRNDGGLVFTPYG-PYAIVMFHKE -FSDADHPATVFGARVSRMILDQf ->[subseq from] serine hydrolase n=1 Tax=Spirosoma sp. HMF4905 TaxID=2682092 RepID=UPI0012F759E5 --nALERKLQAALANFRGDAGVYVHNLRSGKIV-AINADTLFPTASMIKIPIQCGLFDKIH -TGELKYDQELTYKDSLHYDDGIVGSLKEGAKITLSKVVMLMETVSDNTGSLWCQALAGGG -TTINNWLETNGFHQTRVNSRTPGREANRNRYGWGQTTPREMAELVTYIRQGKAISSDASE -EMYRNLGRQYWD-NDGLSQVPPDVKTACKNGAVNQ-SRSEVVFVHAPHGE-YVYCIITKN -QKDETNEGSVLLRTVATTLWHHf ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter malorum TaxID=178901 RepID=A0A087PWV5_9PROT ----LAQIMAKTVSKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT -KGTLHPEDTIVVHNHSLVGKGRFAYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVKAQSLNGIVFGRMIEDFDAN-DQGIRNQVSARGLGDFLQKLDSGQIVGKAQSQ -SMIQIMLGQKF-NDIIPPGLPAGTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG -LP-DEQAGIRVMNTLSHQAYEYf ->[subseq from] Serine hydrolase n=2 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A2A7BG25_9FIRM ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chaiyaphumensis TaxID=307119 RepID=A0A1C4ZC87_9ACTN -------RIGEIFERAGISGCVHVEDVDTGRAV-ALRADEQVVIASVFKILLALEFARQVV -AGQLDPVERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTAREMTRLLRLIWRDEAGPPAACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART -ERLSTRDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2568 TaxID=2512219 RepID=A0A4R1VWF9_9ACTN -----NARIRAVFDDAGARGWLHAISLDRPEDSvELDADVVVPIASVYKLPLLAGFCRLVD -TGELDPCEQLTLSPESRIPGPTGLSILADPVMSLRDLAVTMMTVSDNASADALLNKV-GP -DRLAELLQSFGLEHTRVRRGAAGLVEVYDAANLSAGSARDMTLLLREVWGGGLLSEGQTA -FVRRSMEQQVF-TQRIAAGFPDGVRIAGKTGTFG-ALRHEVAVVTLPGGDAYAVAVFTHA -ARGDLPRVDAAIGEAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus paraplantarum TaxID=60520 RepID=UPI000E714147 ----VSELVEQTMQDVAGRTSIAVMPLTGSQTV--IVNNGAQRAGSLITLFILVTAYDQVH -QNNWQMQDRYTLRAEDKVGGTGTLHTLPAGSLTYAEIAKRMITDSDNTAANIMLDRVGGV -SAINSEVAQLDLKDTTMARRLMDTA-ALKAGRDNYTSVRDVATILQRLANYRLISKRVDQ -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVKNRQGT-FIMTVMAAD -GEREAQT---------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium baratii TaxID=1561 RepID=UPI0009A3EB22 ------KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE -LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM -ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMG -IPNS-VYGTVTLAKSGKMMW--- ->[subseq from] serine hydrolase n=1 Tax=Arsenicicoccus bolidensis TaxID=229480 RepID=UPI0002EAE636 --qTLQRDLKDIVRHAPGRLSIQVVG-PAGVVA-GWDSDREVPAASLVKVLVLVATLREVE -AGRLSLDQTLEIPE-ARVGGAGALSLLPSVALSVVELLRLMVTLSDNDAANLLLRLL-GH -DRVTRCGVELGLRHTHVRRDLMDDGSA-REGRDNTTTATDQAGLLAVLRSGEALGEQQTR -LALALLSEQQH-AYGVTALLPDGVVRGSKPGDLP-GVRHDVALIEAG-GAWAAVAVTATG -MY--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6W252_9FIRM ---SLAQAVTALSNSDSTQYALFVAYPGENREE-YSYQSKQMRSASMIKVFILGTAMEKVR -DGQLSLYQNLVLHSYDKVGGAGVLAGYASGTLTLDTVMRLMITESDNTATNMMIDLL-GM -EEINAYIKRNDYADTILQRKMMDSQAV-AEGRENYTSVNDLGHFFLKLYHRNCVSPELDD -VMLGYLEGQTD-TECFPAALP-GVMICHKTGELY-GLYDDGGIVYQPGK-HFILVGMTEN -YS-SRGRAISILKQMAKAAAN-- ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Clostridium vincentii TaxID=52704 RepID=A0A2T0BBV0_9CLOT ------KEIKKYLESRIGTYGFFFEDLASGFIY-GYNENVKLIAAGCMKLPIAVSLIKAVE -DEKVTFMDKIAISASDKVYGTGIIHEFNARDYTVFELLVAMLIQSDNTAANKIIDIV-GM -DNINKNIQDMGIKNTILNRKTSDE-RIKKSDIENITTAYDLSIIWRHLYKGTYLTQENST -MLIDILRRQQI-KNKLALYIPDDFEISSKTGDKK-GVENDTALIQLQKGT-FVFTVLSTG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Bauldia litoralis TaxID=665467 RepID=UPI000B881D48 ---VLEHRLTHLADSLRADWGIFVHFVNGGGEI-AINADRQQDTMSLIKVALLVTLMRKVE -TGEVDLATRVTLGDDDKRLGTGVLFLFDAGAFTLKDAAWLMIVISDNSATDIVLDAVGGP -EAVNQTMAALGLDQITMTGNALAWFRFGEDRPFALATARSLGLLMLQIHDHRCASPESCE -TMLAMLRGQQL-HSMLPKYMW-GVTAAHKTGNFPPFISSDLGIFTPAAGSPVIISIMTQQ -HRGQRALVEDTVARMGELIIH-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. chh4-2 TaxID=2067550 RepID=A0A2K2TNI5_9CLOT ---TLEKRIAAEIASYDGRMAVYADDLR-GNVI-AIYPDEKFETASTVKTYILACLFDQVE -KGNADLEGMLALKPEHMVEGSGVLCSEPGLKLRVKDVATLMIIVSDNVATNMMIEYL-GK -DTVNKCIRKLGCRDTVLHNDIHF-DR---YRRLGTTTPRDYAGMFIRLAKKELISEAADE -AMMSIFRKQHY-NSMLTGAFPPYISVASKSGSMD-ACRNDGGIITTPYG-SYVLVMMHKE -FSDSGHPATVFGAKVSRMILDQy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CNQ-509 TaxID=444103 RepID=A0A0F7NJ33_9ACTN ------------FAEAGVTGQLHARDIDTGAEL-AVAADTPVSTASVHKVCLLATLYREAE -HGRVDLTAAVDVPAGGRTPGPTGLGAMRDAALSLRDLAVLAVSVSDNTAADVLWDAV-GI -EAVNRTMTALGLTRTTAVQKVRDLYAALDPARTNRSTPRELTALLTAVWRDEVCTGAYAA -DLRRTLGTQAW-GHRLASGFPDDVRVSGKTGTLPT-LRHEIGVVEYPDGGRYAVAVCTRA -AAVTLPAADAVIGTAGRLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI000463C471 ----------------------------GVEEV-AVGADEPVVIASVFKVLVVLEFARQVA -DGQLDPRERVRVTAGDRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL -DTVRLLAEELGLARTRIVGGPRDVLEVLDTQRTNAATPREITRLLRLVWRDEAGPPEACA -QVRELMARQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART -REASRTAVDSAIGAAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. TRM68085 TaxID=2600619 RepID=A0A5N5EL65_9ACTN -----ERTIRSLFDDAGVRGWLHVADLHRSDRV-VVDPDEQVPMGSVYKVALMAAFCRLAD -AGRVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS -FMRAAMLTQPW-THRLASGFPDDLTVHGKTGTFGS-MRHEAGVVDFGDGSVYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. H1 TaxID=2592048 RepID=A0A553UQJ1_9DEIO -------------QGYGGEVGLVISTLEGEELV-SLNAERVFLSASTIKVPLLLLALERVQ -AGQLRLTERHTLKPADRVGGAGILHELGAGLLSLGDLLTLMIIVSDNTATNMVIDLL-GV -DAVNAWLFERGCRQTRLVGKLDQQNAAQRLGERNRTSAAEQAGLLLGLWQGQRLEPPVRQ -LALSILGRQQYRDILGRSLLRPRYQTYTKSGELL-GVHHDVGLLMLP--RPLCVALLSEG -GSDR------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Lentzea albidocapillata TaxID=40571 RepID=A0A1W2BWW0_9PSEU ---------------AGVEGFVHAREIGDGPEA-GHGADEQVVLASVFKIPVAVAYAAEVA -AGRLDETARTRVTPRYRIGGIGTAGCRDDVEMSWRDLALFMMTMSDNAATDVIFHRV-GQ -AAVDAVVA--GLPRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPEACE -RVRAIMAQQIW-PHRLSSGFPADVLVAAKTGTLPS-VRNEAGVVTYPDGRSYAVAVFTRS -QSLDNPAADAVIGRAGRLAVDQ- ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Levybacteria TaxID=1752719 RepID=A0A1F6K7F1_9BACT --qKLKQEVQKLVSSQKGSYSVYFHDLKTDVSF-GINEKQIHTAASVNKLPIIAVLYVLAS -TNKISLDEKITIQEKDIQDGTGKLRYEKQGGYSLKSLAQLALQESDNTAAHVLATRM-GS -DVIQNTIKEWGLTQTHIQN--------------NKTSLYDMYLLFQRIYEGKVARPHLRQ -ELLGFLTDTDI-EDRLPDLLPSSVKVFHKTGDAT-GGIHDVGIVEKDGM-VYFVGVLASD -VSSYEEQTRKTISKISSKIY--- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000506EDB1 ---DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ -ETICRVVAGLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACQ -RVRAIMARQIW-PHRLSAGFPSDVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA -HSDRLPEVDASIGAVARLALDH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0004C93309 ----VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDEQVPMGSVYKIALMTAFCRLAD -AGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHVVLRTV-GA -EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS -FMRAAMLTQPW-THRLASGFPDDVTVHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_38_26b TaxID=1802491 RepID=A0A1F7Y2R9_9BACT -----TFEFRKMTEGLSGIYGLYVIRTEEGSSY-GVNENEVFTAASLIKLPVMIAMYKEVE -DGKINLDTKYKLRALDKTPGAGSLSSKPAGFVTYRDLLRLMGKQSDNTAFTITRNIL-GD -EKIIEIINELGMSQTSLDDN--------------ETTPYDIGMLFESLWNGNIVSEKSRD -ELLENLTDTIY-EDWLAAGLPDGTRFAHKYGREIH-VVNDAGIIFSE--SPIIVVVMSKG -IV--EKEADKVFPELARIIY--- ->[subseq from] serine hydrolase n=1 Tax=Kribbella sp. VKM Ac-2572 TaxID=2512223 RepID=UPI0010517105 ------------------------------ATV-GVDADGVVPMASVYKLPLLAAFCRLVD -LGEIDPLSRLTLDPAERTAGPTGLSVLADPVMSLRDLAVSMMTVSDNASADALLDLV-GL -RRLAELLQSFGLQRTWVRRGTAANLRVYEAANASASSPRDMTLLLQRLWAGELLSAGQTE -FVKATMHRQVF-QHRMAAGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA -ARGDQPRVDTAIGEAARAAVD-- ->[subseq from] Serine hydrolase n=2 Tax=Aphanocapsa feldmannii TaxID=192050 RepID=A0A524RL17_9CYAN ---ALSERFASLTATQDLRAGAYMVVLDDGSFA-QLNPTVPYAAASSIKLPILLLLLQDVG -DGRIDWNQRVIMRAELIGGGAGWMQGQPAGSFPLYEVARDMIRVSDNTATNMIVDLLGGK -EAVNRRWQDLGLTSTVLNNWLPDLGGT------NTSSAEDLCRSLALAELGEQLDLRNRD -RFREIMASSRT-DSLLPAGFLTGSQVLNKTGDIGT-AYVDAAQIELPDGRRALAAFMVVG -SEQTSPRSRQLIRDLATATAQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia ammonioxydans TaxID=260086 RepID=A0A1I5FJE6_9PSEU -------------------------------EV-AVGADVPVVMASVYKILVLVAYCRAVD -EGTIDPREPVVVPPARTPGGTGLSALADPVTMSWRDLVTSMVTVSDNAAADVVHTRV-GR -ERVAALPAELGLPGTRVAGGTEDVFAALNPAFGSSTTAADTTRLLALLWRGELTSAAGTA -FARRVLAAQIW-PHRLRAGFPATAAVAAKTGTVG-AVRNDVGVVSYPGEHPVAVAVFTHA -ARASVPRADAAIGAAARAAVQ-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=2 Tax=Clostridium baratii TaxID=1561 RepID=A0A0A7FWA3_9CLOT ------KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE -LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM -ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Acetobacter indonesiensis TaxID=104101 RepID=UPI000A3AA340 ---TLAHQIETTVQGQKGLFAVYAARVGARPEV-CLNCDHLINAASTIKLFVLDTAYKSFA -SGTLHPTDLIRVHNHSLVGKGTFAYAQQGKEVPVSELLRVMIQYSSNLATNLMIEKL-GV -FPIRDVVKEQALDGIVFGRMIEDFDAD-AQNIRNRVSARGLGEFLQKLDQGQIVGKEASQ -SMIAIMLGQKF-NDIIPPGLPAGTPVAHKTGWVH-GVKNDAAIITLPDGSHYILVVLTSG -LP-DEAAGVKILNVISQEVYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1G7TFQ6_SELRU ---DLNRNIARILGGDSGRYAIYFWRPAEEEEP-FLYQNRPMSPASMIKVFIMAAVMQEVH -DGRLSLEEKLTIQEADVVGGAGVITWNIGESRSIRELVSGMITNSDNTATNMLIDRL-GM -DKINRYIQGHGYGDTQLVHKMMIGN----GGRKNFSSVKDLGKLFSRLYYHQLVGDTEDR -FMELVLSGQKD-RECFNAALP-DFTIAHKTGEVT-GLYDDGGIFYGRQGD-FVLVIMNEG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium TaxID=1485 RepID=UPI000665F2FF ------KEIKRYLESRIGTYGFFFEDLSSGFIY-GYNENVQMVAAGCMKLPIAVSLIKAVE -DKKVDFMDKIKIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM -DNINSNIKEMGLKNTILNRKTSDERQS-KDGVENITSAYDLSKIWKHLHNATYLNRDNST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLPKGN-FVFTVLSTS -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces niveus TaxID=193462 RepID=UPI0009908979 ---------------LGARLWLHARCVDCGRAA-GHAEDEPVVLASVVKVLLVLEFFRQAA -AGQLDPAERAVVRAADRLGGTGTAGFHDDVELSLRDLALMTMSVSDNTAADILFRRV-GR -DTVQALARQLGLERAQVTGAPREVLEALDPARTTSATPREMTRLLSLVWNDRAGAAAACA -GVRELMSLQVN-GARLGAAFDRFTTVAAKSGTLP-GVRNEIGVVTYPDGARYAIAVFTRT -TSTRRPDLDTAIGGAGREVVE-- ->[subseq from] Uncharacterized protein n=2 Tax=Fusobacterium varium TaxID=856 RepID=C6JLR6_FUSVA --eKFEKKLLEILKKYNKKYGIIIKSLESEFFL-KVGNMEAYPAASLIKLPILYELFNNSK ----YNLDEKIEITLKDKVGGFGIIQYHNNVKLSLRDLAILMIILSDNTATNILIDIC-GM -DNINFTLKKLGLKDTKLRRKMMDLKSK-NMGLDNYTSPYDMIKLLEVLNK--------NE -EIISIMKKQLC-NNKISHFIEKKIDFAHKTGDLPQ-IEHDVGIFDIEDKK-IIVVVMTKN -FENR--DEIELNNKVGEFI---- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. CY41 TaxID=2608686 RepID=UPI00135B431F ---------QAIFRAAGVEGWIHARCVHCGAEA-GAGADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRMRTRAADRLGGVGTAGCADDVELSLRDAAYFALTISDNTAADLLFDRV-GL -DNVRSLLRELDLPATRVVGPPRAIVQALDPRRTTASTPREMVRLLTLIARDQAGAPEACR -WVRDLMRQQVN-WYRLAAAFPPDVQVWAKTGTLP-GVRNEIGVVEYPDGKCYAVAVFTRA -ATQRLPEVDRAIGAAA------- ->[subseq from] Uncharacterized protein n=1 Tax=uncultured Paludibacter sp. TaxID=497635 RepID=A0A653AGG9_9BACT --kKLTKLIENQVAGFNGTIGVYVKNLKTDKEA-FFNADTVFPTASTIKVPIMVAVFDKIE -KKELKYYQPLTYSKKELYKDDGLIASLRDSTVPLSIVQMLSICTSDNSASLWLQELAGTG -TVINELMENIGLKDTRVNSRTPGREKIREIYGWGQTTPREMTQLLEKIRNREIISPAACD -EMYRILGTIYY-RDRALSQIPPTINTASKQGMVS-AARSEAVLVNAPHGD-YVFAVYTKN -QKGKDNEGRKQIIQISALLWNYf ->[subseq from] serine hydrolase n=1 Tax=Nocardia amikacinitolerans TaxID=756689 RepID=UPI0008316350 -----EERIREIFAELPVRGQFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD -AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP -DTPALLTAELGLGATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWRDEAGSPAACA -ATRDLLRRQMF-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS -DETRRIDVDLAMARSARLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Salinimicrobium sediminis TaxID=1343891 RepID=A0A285X5L6_9FLAO --kELEKALKEITSDFNGDVGIYVYNLKTNKEA-AINADTIFPTASVIKVPILLGVFQKII -NGELKYNEPLVYDAKRAYGGSGLMQFYKDSTTDLRTSLALMMGYSDNTSSLWNQELAGGG -EGINTLLESLNFQDTRVNSRTKGREDIWKRYGWGQTTPREMTDILVKIRRGEMFNSAASE -EMYRLMTNSFY-TDYALSEIPPYVQSASKQGMVDD-SRSELVMVNAPSGD-YAFYFTTKN -IEDEENEAWELSREISAFLWNYf ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. L-9-10 TaxID=1478131 RepID=A0A4Q4DL75_9ACTN -----------------------------RAEV-AIGADEPVVLASVFKVLLVLEFARQVA -AGQLDPRERVWVTADDRLGGWGTAGCLDDIGVSLRDLAHFAMSVSDNSAADLLLARV-GT -DTVRLLAEELGLHRTRILGGPRQLLEVLDPERTSASTPREITRLLELIWRDEAGPPEACA -QVRELMGRQVF-RHRLVSGFPDEVRVAAKTGTLP-GLHAEAGVVHYPDGGRYAVAVFART -GDTNRTAVDSAIGAAARIAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum subsp. argentoratensis TaxID=271881 RepID=A0A512F013_LACPN ----VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS -GER--TAQTSAMNDLGQVLYR-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. YIM 132580 TaxID=2691958 RepID=UPI00136A7094 -----EAAIRALFDDAGVRGWLHVAELERSARV-VIDPDEQVPMGSVYKVPLMTAFWRLAD -VGRVDPSHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -DVVDRVCAELGLPHTRIHGGVVGTFDVYDPAYKASSTPAEIARLLRAIWTDEAASPGSCS -LMRAAMRTQPW-THRLASGFPDDVTVYGKTGTFGS-MRHEAGVVELADGGLYTAVVFTQA -ARADLPRADAVIGAVARAAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Gordonia rubripertincta NBRC 101908 TaxID=1077975 RepID=L7KEF0_GORRU ---RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD -RGEIDLTSPVTVDPTRWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL -DRVREDLIGLGATSTRIVGGVAELHEAYDAAYTSSSTPRDCSTLLSAVWTDRAASAEMCA -FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTRS -ARPALPQVDRAIGELARTVVT-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus hoagii TaxID=43767 RepID=UPI00080B4C3B ------ASIADVCDDANATVAFHVRSLDGNLEI-GSGADARSVTASTYKVPVMLEVAAQAS -EGRIQLADRIKVPADRRTIPSGISAMTDEVEVSIRDLALLMMQVSDNTATDILQEMV-GT -ENIMSRLRALGLNSTSITTDCEGIISSLNARGGNTSTPREMTELLSLIWTDKAADAEACA -EVRRVMGLQFA-PHRLSSAYVDGPTISGKTGTFLAGVRNEVGVVDFGDEGLYVVAIFLRD -KNNYNSKVDAAIGKIAALAI--- ->[subseq from] Peptide methionine sulfoxide reductase MsrA n=1 Tax=candidate division BRC1 bacterium HGW-BRC1-1 TaxID=2013722 RepID=A0A2N2PMS4_9BACT ------GKLEQIVAGHEGRMGLSVVNEDTGETF-EVNADAEFVTASTIKLGVLGTAFDLLT -SPSKSYYSTMVYDGSTSAAGAGFIQNYKGTRIELKELVHFMITASDNTGTNMLTKWVGGP -QAVNAWLASKGLARTRMNATIGGGQVADQALREGVTTPAEMRRLMQMYAEGKAVDTTASE -EILRVLGHQYF-DDDIASQVPPTMWVGSKSGAVN-ASRSDVAIMSTPGG-LIVMAVYTDN -NREDDNAGEVSIRRVAKEVFDHf ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A3E2U8F9_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAS -RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL -DTINACIREMGFAHTVLHNPLH---FDIYN-NLGTTTPRDYASLFAQVAKGTLVSAKASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Williamsia sp. 1138 TaxID=1903117 RepID=A0A261CZM9_9NOCA -----GQRLREIFADAGCAAWLHARTIGPQREF-GWYADDPVVMASVYKLPLLAALCVHAD -RGDINLRDTITVDPRECAEPTGIATLHDPITLSWRDLAVQMMVVSDNAAADVILAEV-GL -DGVREVLNGAGLHSTHVVGGMAQVQQAYDPAFASATTAREATCLLDLIWTDRVASVDSCE -FIRTTMRKQAW-KQRISSGFPLGATVAGKTGTLG-AIRNEVAVVEYPGEHPVAVAVFTHA -ARLSLPTVEAAIGQAARVAVN-- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K309 TaxID=2530384 RepID=A0A4R4VNT9_9PSEU --------LA--ELELPGRVGIASWDLRENVPV-LRGAEVEVHSASTIKVLVMITALRAVA -DGRLDLDAQVELP-ADRTKGTGVLFEVPSVPASLRDLINLMIVISDNAATNAVIDQV-GF -AAIAECTADLGCTGTRIERHIMDTEA--PGVLR--TTALDQARVLTALAEGTALPPQLTA -HALTVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ -LTD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Runella sp. HYN0085 TaxID=2259595 RepID=A0A344TQB7_9BACT --kKLTAQLQEAIKGFRGDVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIA -KGELRYNAILTYKDSLHYEDDIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG -KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELFAMIRQGRAISPDASD -RMYRNLTRQYWDGEGL-SQLPPDIKTACKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN -NLTSQNEGYVLLRKISKQLWNYy ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 06-418-5 TaxID=2022507 RepID=UPI000B9AE07B ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAVARAFD -KGSLTATDSVRLVPAQCSPPTGIASFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQSIGHAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=candidate division WWE3 bacterium TaxID=2053526 RepID=A0A3A4ZB65_9BACT -------ALKKVLEQQGTKYSLYIEDLATGKTY-AYNAQERTYAASMYKVPVAAAVLKSIQ -DRNLSFTTELIYAQSDYADGTGVINRQFGTKFSVEQLLTHLLDDSDNTAQNMLLRKV-SK -AQVGTLISQ------NIDNPSQSIFAA-----ENTATATEMATFLKNMYKKDVLTQENKN -FLFNEMKQTAF-DDRITQHLKPELSFAHKIGNWDTGSWHDCGIVFGSNDK-YVVCVMSRG -TT--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=A0A0N0TKG1_9ACTN ---------------------LTVGQLGGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERILVTADDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRELVEVFDPLQTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA -DRPRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 11-1-2 TaxID=1851167 RepID=A0A222TB22_9ACTN ----IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPGHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRLASGFPGDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Nocardia niigatensis TaxID=209249 RepID=UPI000314DF16 ----------EIFRTAGVEGRVHARCFDCGGEF-GWAADEPVVLSSVVKVPLVLEFARQVA -AGQLDPSDRVRATAADRLGGVGTAGCHDDVEFSLRDAAWFALTVSDNTAADLLFDRV-GV -DNVRSLARELGLTGTRIMGSLRDILYAVDPLRTTAGTARDMTRLLWLIGEDRAGAPEACR -FVRDLMRQQVY-GHRLPSAFPPDTDIWSKTGTLP-GIRNEIGVVGYPDGSRYAVAVFTVS -HSGRQPVVDRAIGAAARLAVE-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI0006BF6A39 --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAMA -NGRYALEQPLALPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNAATNALIDLL-GF -DAINQWSQRARLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter ginsenosidivorans TaxID=398053 RepID=A0A5B8V2B4_9SPHI --kKLTLQLQDAVKGFNGQVGIYVKNLKTGKYA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELQYNQKLIYRDSLLYPGEDILGSFKDKDIELSKAVLLMITMSDNTASTWLQKIV-TG -EYINNWLEQNGFKVMRVNSRVKGREKIRARYGWGVSTPREMCRLFTMIRDGEAVSPAASE -RMYRNLGRIFW-DDKALSQIPPYVNTASKQGALDE-SKSETVLVNAPHGD-YVFSIITNN -NKDQDNEADILIRKVSALLWHYy ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007EE5DBF -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVVMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FCB2F6C -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVVMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007BC614D ----VTDLVAQATKGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. An77 TaxID=1965655 RepID=A0A1Y3TTL1_9FIRM ---TLEKRIAAELYSYHGQMSVFVDDL-QGHTV-EMGADEPFETASTIKAYILAALYLQAS -RGKASLEDTVTYRPEHFVDGSGMLRAGVGAALKVKDAATMMIICSDNIATNMIIDYL-GL -EEINRCIQELGFEHTVLHNPLH-FD---RYDKLGTTTPRDYAGLFARVARGTLVSREASA -DMLAIFRSQHY-NTMLTGNFPPYIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKN -FDD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces triticisoli TaxID=2182797 RepID=UPI000DD9C6E6 ------------------------------REV-AVGADTPVVIASIFKVLLALEFARQVV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVRLLAEELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLQLIWSDAAGPPEACA -FVRDLMGRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGAHYAIAVFVRT -HDASRPTVDAAIGRAAGI----- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=UPI0006AE8055 ---------------------LTVGQLGGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERILVTADDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRELVEVFDPLQTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA -DRPRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Haloactinopolyspora alba TaxID=648780 RepID=A0A2P8E5P7_9ACTN ---ALRGELDALARRSPGRWAFSVRE--SGRPVaSVSGSVVMPAASTVKVALLALVLVDVA -AGERSLDDPLPVP-DRRAGGTGVLDLMPSVRLPLGEALELMIGVSDNTATNMVIDAL-DL -DEAGRRIVALGASSTLLRRHLMDTDAA-RAGRDNVTTADDQALILDRLAGPDLLPQPWRR -YALDVLGRQQF-NDRIPAGVGPDVRCAHKTGELP-GVRHDVGVLEFDGR-SVVLAALGSE ------------------------ ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=uncultured Faecalibacterium sp. TaxID=259315 RepID=A0A1C5M2W9_9FIRM ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAN -RGKADLEEDITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007EB3325 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GER--TAQMVAMNELGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Edaphobacter sp. 12200R-103 TaxID=2703788 RepID=A0A6B9YLR0_9BACT ---SLQQSLAAIAATHKGHVVLYAKQLNTGKVV-ALDSDQPVQTASVIKLAILFEAMEQVR -DGKAHWNEKLTLKKDDGVSGSGVLTFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRF-GT -SAVNARIAWMGLKDTHLYKKIGKPATDQPKFGLGKTTAHEMETIMERIGRCELGKPGEPA -QPGDIMLRNQFYRNTIPRYLEEGSGIASKTGSLN-AVRNDVAIVAGKDG-PIIISIFTYG -NETADNEAEIIIARLARKIVEAw ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DC9421 ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFLWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Beta-lactamase n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0KXR1_9BACT ---EITSAFKDKTKDLSGIYGLYVINLNNGASF-GVNENEKFQAASLIKLPVMAGMYIEDD -KGNIDLDEKYTLRTSDKVKGAGSLYSKPAGYITYRNLVELMGKQSDNTAFNIFRRIL-GE -EKIGEIIGNIGMMDTSLN--------------ENITTPRDIGIYFEKLWRGNIVNDLSRD -ELLDALTDTIY-EDWLIKGIPKEVRVAHKYGRELH-VVNDAGIVFAE--KPFVIVIMSKG -VV--EAEADKAFPELTKIVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Megasphaera sp. An286 TaxID=1965622 RepID=A0A1Y4CIE3_9FIRM --------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE -AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGIVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] serine hydrolase n=1 Tax=Haloactinopolyspora alba TaxID=648780 RepID=UPI000D0DCB31 ---ALRGELDALARRSPGRWAFSVRE--SGRPVaSVSGSVVMPAASTVKVALLALVLVDVA -AGERSLDDPLPVP-DRRAGGTGVLDLMPSVRLPLGEALELMIGVSDNTATNMVIDAL-DL -DEAGRRIVALGASSTLLRRHLMDTDAA-RAGRDNVTTADDQALILDRLAGPDLLPQPWRR -YALDVLGRQQF-NDRIPAGVGPDVRCAHKTGELP-GVRHDVGVLEFDGR-SVVLAALGSE ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Halorussus sp. ZS-3 TaxID=2650975 RepID=UPI001301802F ---------DSYREKLDGRLGVFLGFPDGPDDFyRRAATTQFASASVVKLPVLYALLAKYD -GRLSELDAPREIAPENRVAGSGVLHLL-SATPTLRDLARAMISISDNAATNELVDEL-GM -DRIESAAADVGMTDTRLRRKMMATLGWPDGEPANATTPLDCARFFADFHSEATLSAAAYD -EMAVPLEAQKH-AMKFPRYLPRDATVVHKTGELPE-AALDTGYLRPPDGNPLVFAVLADE -LT-TGADGADAIAEIGEAVYTWf ->[subseq from] serine hydrolase n=1 Tax=Hamadaea tsunoensis TaxID=53368 RepID=UPI0003FA5228 -------------TSTGGTVSIWAGPIDGPPAY-AWNEDAGHYAASTMKVAVMAAAFRAAE -RDELDLGAQVDIVNRFTSAGAPAYTSRIGGRADLGWLIERMIVRSSNLATNLVIEQLGGT -AGVNEVWRAVGAKRSVTGRGIEDAAA-REAGVTNTVTAADLAALFSALARHDIATTESCD -AMLRILLAQEY-RDDLPAGLPEGTPVAAKNGWVT-GVRHGAAVVLPDDEPPFTLVICTST -DL-GEAEGAALVARIAEAAWR-- ->[subseq from] Serine hydrolase n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B2UPX9_9ACTN ---AVADRIAAAFADAGVDGVVHAVDIDRGTEA-GYEPDRLVSTASVHKLCLLLALHRLAA -AGRIDLTEQVECAVEGRTPGTGLAAMLDPSRLSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRLTRAVESFGATQEALDPTHGNRSTPRELTRLLRALWRDEFLPAAHGA -AVRRLLGLQVW-PHRLASGFPDDVRVSGKTGTLPT-MRAEAGVVEYPDGGRYAVAVFTRA -ADHVLPAADAVIGVVARVAVD-- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI00142242AF ---ETSAQIAEIFADAGATGFLHAREIGDGPEV-TVGADDPVVLASVFKILVLTAYVRAVA -AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT -EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAATAEACR -QARDIMALQIW-PHRLTAGFPSDVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium sp. Marseille-P9312 TaxID=2580425 RepID=UPI00122C7A99 ---TLEKRIAAELYSYQGKMSVFVDDL-HGHTV-EIGADEEFETASTIKAYILAALYLQAG -RGKASLEEKITYKPEHFVDGSGMLRAGVGASLKVKDAATMMIICSDNIATNMVIDYL-GL -ATINACIREMGFAHTVLHNPL---HFDIYND-LGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIVHTPYGE-YVIVLMNKD -FHD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Pseudoflavonifractor sp. Marseille-P3106 TaxID=1871015 RepID=UPI0009BBA247 ---ELNAYLHREIEAFPGQTSLLVSDPLSPEPLhAWQETLRVPSASTIKTPILLTALEQVR -QGMLSLTDPMTVSPDCVLPDTEVFDR-GESVYSLGELLYWMIVESDNTATNVILDAL-GF -DAVNEYCAMLGLENTLCQRKMLDFAAA-QAGLDNFTSAADQRRLFSLLHGGQILNPGLRK -IALSILCRQRS-MDCMLRYIPDAVEVAHKTGGLN-GVAHDCGLFLLPRR-PLFVGIFTWD -GPDGDPGQKRYIGRLAKAVYDFy ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536DFC8_9CHLR ------------------------------------------------------------- -------------------------------------EVGAMIAVSDNSAANQIVDAI-HP -QAVNDTLGRLGLGGTHFMNLFSDARSA-ASPGLNQTTPANMAHLLELIATDQIVSPQVSA -DIRTLLGRNVD-RSKLVRLLPPDARVEHKSGWYE-GVANDAGIVTVDRVTRWVIAVFSEN -LP-DAETGNQLVAAISKAVYDAw ->[subseq from] serine hydrolase n=1 Tax=Segetibacter koreensis TaxID=398037 RepID=UPI00052674F2 --kKLTRQLEKLVEGFNGQVGIYVENLKNGKSA-AINPDTLFPTASMIKVSIQCGLMDKIE -KGLLKYNQKLVYNDSIVYPGEDILGSFKNNDIQLSKVALLMITMSDNTASRWLQNLV-GG -DYVNNWLGENGFINMRINSKVAGRENMYNTYGWGVTTPREMCRLFTMIAKGQAVSEAASE -RMVRNMGRIYW-DDKALSQIPPYVHTISKHGSLNE-SRSETVLVNAPHGD-YVFSVITKN -LKTPDNEAIVLIKNLSSLLWQHf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FUG8_9PSEU ---RIADEIEAVFAAAGARGFVHAREVGDGPEV-AVGADDPVVLASVFKIPVALAYAGEVA -AGRLDETERTLVTARYRIGGVGTAGCADDVEMSWRDLAHFMLTMSDNAATDLVYHRV-GQ -EAVDRVLADLGLVRTRLIGCCEDLFAVLDPERTTSSTPREITALLDAIWTDRAGDPAACD -RVRKIMAQQIW-PHRMSSGFPAGVAVAAKTGTLP-AVRNEAGVVSDVDGRRYAVAVFTRA -ESDRLPAVDASIGTAARLAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coxensis TaxID=356852 RepID=A0A1C5JC13_9ACTN ---AVQQRIAQVFARAGGSLHVVPVDGPDGREI-ALDADRRTVIASVFKILLVLEFARQVA -AGQLDPTERVLVTAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELELGRTRVRGGPRDLVEVFDPDRTSSSTARDLTRLLTLIWRDRAGPAVACA -TVRELMSRQLV-RTRLASGFPPGVRVVSKTGTLP-GLYLDAGVAEYPDGARYAMAVLVRA -AHTHRTDVDLAMGEAARIAVQ-- ->[subseq from] serine hydrolase n=1 Tax=Runella limosa TaxID=370978 RepID=UPI0004905853 --kKLTALLQQAIKGHEGNVGVYVRNLKTNKIV-EINADTLFPTASMIKVPIQCGLFDKIS -KGELKYNAILTYKDSLHYDDGIVGSLKDGAKIPLSEVVMLMETVSDNTGSLWCQALAGGG -KSINEWLDKNGFTATRVNSRTPGREANRTRYGWGQTSPREMAELIAMIRAGKAVSPDASD -RMYRNLTRQYWDGEGL-SQLPPEIKTACKNGAVNR-SRSEAVLVHAPHGE-YVYCVITKN -NKTSNNAGYVLLRKVAKALWTYy ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000B3CDCA0 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGNLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQMVAMNELGQE----- ->[subseq from] Beta-lactamase class A n=1 Tax=Pontibacter chinhatensis TaxID=1436961 RepID=A0A1I2S8J3_9BACT --dELSQQITTTLGAQEGTFAVAFKDLQTGKEL-LLSAQESFHAASTMKTPVLIEAYKQAS -EGRFSLSDSILIHNESIVDGSLYSYTLIGQKRPVSELLYKMIIQSSNLATNLIIEEL-DA -KQVTLTMRELGAQAIQVLRGVEDKK-AYERGLNNTTTAYDLMLLFEQIAAGKAVSPEASQ -EMVRILLDQRH-REIIPARLPEGVKVAHKTG----------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535AJB8_9CHLR ---DLVAHLDQLSEAFPGGVGLWISDPNASKPLyTRNPDEQVITASLYKLGVLMETERRVE -AGELHYNDIITIQPEDVSEDGSF--EAVGTELTIDQALEAMITISDNGTAQALWHLL-GG -ANIDATLAKVGIPDFHV---------AFDSSEDNVATPRAIAQFFTLLAKKQLVSLAASE -RMLARLERQEI-NDRLPAALPDGVVVAHKTGNLL-GLAHDAGIIFTPSGPRIVVAMTWDA -YD---EDANAFIANVGALVYS-- ->[subseq from] Serine hydrolase n=2 Tax=Faecalibacterium TaxID=216851 RepID=A0A3E2TAI5_9FIRM ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGALVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535GF80_9CHLR ---DLVAHLDQLSEAFPGGVGLWISDPNASKPLyTRNPDEQVITASLYKLGVLMETERRVE -AGELHYNDIITIQPEDVSEDGSF--EAVGTELTIDQALEAMITISDNGTAQALWHLL-GG -ANIDATLAKVGIPDFHV---------AFDSSEDNVATPRAIAQFFTLLAKKQLVSLAASE -RMLARLERQEI-NDRLPAALPDGVVVAHKTGNLL-GLAHDAGIIFTPSGPRIVVAMTWDA -YD---EDANAFIANVGALVYS-- ->[subseq from] Secreted beta-lactamase n=2 Tax=Streptomyces violaceusniger TaxID=68280 RepID=G2PAF4_STRV4 ----IEKRIAEVFAEADAEARLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAD -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRLACGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFAGT -ASAARTAVDAAIGRAARLAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPLOWO2_01_FULL_48_11 TaxID=1798395 RepID=A0A1F6ARK2_9BACT --eELQKKIQAQIGNTWKNYSIYVKDYTSDFSM-GINDTVIFTAASVNKIPIIAALYWQVQ -NQAIDLDTSVTIQASDVQYGTGTIQSPPGSTYSVKTLAKLMMQQSDNTAAYILANYTVGL -DTIQTLVNRWGLTQTDIIN--------------NKTSNKDMEILMDKIYTGKITNTAYTQ -EMLAFFKDSDF-EDRIPALLPKGTTVYHKIGTEV-GVMHDAGIVHQGNL-TYYIGIFTSD -VS-DEPTTIKLIAEISKAVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium paraputrificum TaxID=29363 RepID=A0A173Z5W8_9CLOT ------KEIKRYLESRIGTYGFFFEDLSSGFIY-GYNENVQMVAAGCMKLPIAVSLIKAVE -DKKVDFMDKIKIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM -DNINSNIKEMGLKNTILNRKTSDERQS-KEGVENITSAYDLSKIWKHLHNATYLNRDNST -MLVDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLPKGN-FVFTVLSTS -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004BFF44D ----VQERIEAIFAAAGVTASMHAVDLDSGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCVDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPILAVELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPPAACA -MVRTWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces qinglanensis TaxID=943816 RepID=A0A1H9T153_9ACTN ---------------------VAELH-RPSARV-TVDADGLALMGSVYKVPLMVAYCRQVD -AGALDPRQRLTLSAGDRLPGPTGLSLLRDEVMSLRDLVVMMMSISDNAAADAVLRQV-GT -AAVEETCAALGLSRTRLDGGAAGSLAVYDPAWAAATTPAEMAALLRAVWRDEAASPGSCA -FMRATMGLQPW-QHRLAAGFPDEVAVYGKTGTFG-AMRHEAGVVELADGRGYTAVVFTQA -ARADLPRADAVVGAAARTAVEH- ->[subseq from] Beta-lactamase class A n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=A0A1H6GHC0_SELRU ------ADLQVLLEERMADYAIYYLRPDLEQEP-FVQSSRQQQPASMIKLFVMAKAMEDVK -AGRMSLEEPVTLQKEDVVGGAGLTIYNLGTPITVRELITLMIQASDNTATNALITKL-GM -GEINAYLEREGYHDTKINHKMMLQKVVVTKLPDNLSSVQDVGTLFTRLYKHECVGPQEDE -IMIDILKGQED-TACFNAALP-DWQIAHKTGEIS-GLFHDGGIFYGSEGN-FVLVIFCEK -YA--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora flava TaxID=95161 RepID=A0A1I6UI74_9PSEU --------------EFPGRVGIASWDLREGVPV-LRGAEVEKHSASTIKVLVMIAALRAVA -DGRLDLDRLVELPRERIRGTGVLFEMPSVAAVSLRDLIALMIVVSDNGATNAVIDEV-GF -PAIADCIADLGCTGTRVERHIMDTES--PG--LLQTTALDQARVMAALAGGEALPARQTE -HALDVLARQQV-VDRIPLRLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLIDR -LTD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora echinaurantiaca TaxID=47857 RepID=UPI000B5AD72C ---------------------------DGGREV-AVRADEQVVIASIFKILLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELGLSRTRIVGGPRQLAEVFDPERTTSSTAREITRLLGLIWRDEAGPAEACA -MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM -ADTRRIDVDLAMGEAARTAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. BL8 TaxID=1354301 RepID=T0PN06_9CLOT ------KEIKRYLESREGNYSFYFEDLKGGYTY-GFNENVKMPAAGCIKLPIAMALLKEVE -NGSVSLDDLVSIGDEDKVSFFGIIHEFSEKQYTLKELLVAMLIQSDNTAACKIINTL-GM -NRINNIINNMGLKSTKVNKYPSEIK--LEDNNENITTSYDLSQCFKILNNNTALNKEHSK -LILDTLKRHQL-TTRIPFYFPREIKTANKIGTLES-VENDTALLNISKGD-FVFTVLSNN -LP-TNVYGITTIARTGKMMFD-- ->[subseq from] Beta-lactamase n=2 Tax=Acetobacter TaxID=434 RepID=A0A149R674_9PROT ----LAQIMAKTVSKQPGHFAVYAARSGQAPDV-CLNCDDLINAASTMKLFVLDTAYEAFT -KGTLHPEDTIVVHNHSLVGGSFALYAQAGKPVPVSELLRVMIQYSSNLATNLMIEKL-GV -LPIRSVVKAQGLIGIVFGRMIEDFDAN-DQGIRNQVSARGLGDFLQKLDSGKIVGKAQSQ -SMIQIMLGQKF-NDIIPPGLPASTPVAHKTGWVD-GVRNDAAIVTLPDGKRYILVVLTSG -LP-DEQAGIRVLNTLSHQAYEYf ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DF3BBA ---TLEKRIAAELYSYQGRMSVFADDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFLWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Beta-lactamase n=1 Tax=Terrisporobacter othiniensis TaxID=1577792 RepID=A0A0B3VXY7_9FIRM --------IINKLKNMKGDVSFYYKNLVTQEII-KYNEEKPMLAASVIKLTVLVECFNQIK -KDIIRKDDIFITKEEDKVPSCGALNYMRENLITLEDLYVLMIILSDNYATNILIDKL-GI -DNINKTIKEIGLKNTVLNRKMFDSDKA-ALGLENYISAGDIAYLLEKMYNKELIDEKSSE -EMINILKNQRL-NSKVPFFLQPKVNIAHKTGEDTN-ITHDVGIVFD--KEPFIVCFCGNN -V--NVPEYERLMQDVT------- ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI000E3F1D9C ---TLEKRIAAELYSYQGRMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSREASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinaurantiaca TaxID=47857 RepID=A0A1C5JQ90_9ACTN ---------------------------DGGREV-AVRADEQVVIASIFKILLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELGLSRTRIVGGPRQLAEVFDPERTTSSTAREITRLLGLIWRDEAGPAEACA -MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM -ADTRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000930E809 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTAAQ-KAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium maritypicum TaxID=300020 RepID=UPI00124B162B ---------ADIFADAGATGFLHAREIGDGPEV-TFGADEPVVLASVFKILVLTAFVRAVA -AGELDPTERTTVTARYRIGGVGTAGFADDVEVSWRDLALNMMSMSDNAATDIIYHRL-GG -EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQTW-PHRLTAAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA -ASLV-DRQPLVDASIGRAA---- ->[subseq from] Beta-lactamase n=3 Tax=Lactobacillus TaxID=1578 RepID=A0A165QRY5_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0003987444 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Spirosoma terrae TaxID=1968276 RepID=UPI0013D2C2EA --qSLDQQLQTAIAGFQGDVGIYVHNLRTDQRV-AINADTIFPTASTVKIPIQCGLFDKIH -KGELSYNQELVYKDSLHYDDGIVGSLKDGAKIPLSHVVMLMETISDNTGSLWCQALAGGG -TAINNWLATNGFQETRVNSRTPGREAYRSRYGWGQTTPRELAQLLTYIRQGRAVSPDASE -EMYRNLGRQFW-DHNGLSQIPSSVKAVTKNGAVNQ-ARSEVVMVHAPHGD-YVYCVMTKN -QKERTNEGSTLLRNVAAILWHYf ->[subseq from] Beta-lactamase class A n=1 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5PX93_9ACTN ----VEGELKDAFAAAGVTGFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA -TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -EKINAGTAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPAAACD -EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL -PGAENPAADAVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007D8DEC5 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVVMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536QH90_9CHLR ---DLVKQLDGLVSSFPGGAGIWIADPTVATPLfAHDAEEQVIAASLYKLGVLAEAERRVD -TGELHYADTVTIEPDDITADGSF--EYAGTELTLDEALEAMITVSDNGAALALWHIL-GG -ANIDATLEKAGISNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISPAASD -RMLARLERQQI-NDRLPAQLPGGVVVAHKTGNLS-GVTHDAGIIYTKTGPRVVVAMTWDA -LD---EDAANFISSIGSLVYS-- ->[subseq from] Putative beta-lactamase n=1 Tax=Prochlorococcus marinus (strain MIT 9313) TaxID=74547 RepID=Q7V6M1_PROMM ---TLSNRWRELAKQQDLQASAFLLVLDDGRYA-ELSAETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacterium sp. S111 TaxID=2483795 RepID=A0A4Z0IXN7_9MICO ----LDTAIERLEDELGITCFVHARDLDDSAAV-GVREDEPVVTASVFKLPVLVEACIRMS -TGEVPAERRIVLGPEDFPVGSTGLAVFSDAVVSFRDLCLSMMTVSDNRATDVVMDIL-GR -ARVNARMRELGLTSTVIEGDCRHLFDTLDPGRTNRSTPAETTTLLAALWRDEGLPASACA -EARRILGLQVW-SHRLRRGFSDEVTVSGKTGTLPY-IRNEAGVVEFPDGGRYAVAVFLRT -PSPRGPRFDDAITDLAAAAV--- ->[subseq from] serine hydrolase n=1 Tax=Selenomonas ruminantium TaxID=971 RepID=UPI0006903838 ------ADLQVLLEERVADYAIYYLRPDLEQEP-FVQSSRQQQPASMIKLFVMAKAMEDVK -AGRMSLDEPVTLQKEDVVGGAGLTIYNLGTPVTVRELITLMIQASDNTATNALITKL-GM -GEINAYLEREGYHDTKLNHKMMLQKVVTTTLPSNLSSVQDVGTLLTRIYKHECVGEQEDE -FMVETLKGQED-KICFNAALP-DWQIAHKTGEYS-GTFHDGGIFYGPEGG-FVLVIFCEK -YA--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A0M7ICJ9_ALCXX --qHVDAALAPLLAATPARVSLSLRDLDGNIVL-AHHADRVQPSASIIKVPILLALLEAVA -NDRYALEQPLALPACGGRAGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWSQRAGLAASRLQRRMMDTAA-REAGRDNFTSADDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Desulfallas gibsoniae DSM 7213 TaxID=767817 RepID=R4KK74_9FIRM ----LQNQITGYLDKQPGIYGLYFIDVKSGQEF-GYNSHTVFHAASTFKLPMNLYLYLAAD -HGQINLAEQLLFTDKHLEGGTGILQNKSPGEYAVAQLADYSILYSDNVATNILLDRL-GK -ENVKEFMRSMGGQVVD--------------NEQNITCPYDLALYMRQALH--FAGQPAGE -KLLNNLFDNKL-KDRIPAPLPPDIKVANKIGTWPTNTYNDVAYVAHPEQ-PYILVVTCKD -TP-GYGEALAVIHHLSKLVYR-- ->[subseq from] Serine hydrolase n=1 Tax=Haladaptatus sp. R4 TaxID=1679489 RepID=A0A166TDP7_9EURY -----AGYVERYDDEIEGELGVFLGPTDDGEVVyARDETRVFQSASTIKLPVLYALYERYD -GQLDELDRPCPLSSENRVGGSGLLH-LLDATPTLEDLAAAMISVSDNAATNQLIDHL-GI -ESVNDEAARLGMERTRLARKMMATLEIPDDEPTNATTPLDCARFFADFVRRRTLSTEAYE -RMRVPLSAQKD-TSMIPRYLPYETEIAHKTGWLPT-AALDTGVLSVPDREPLVFSVFIDG -VGQNGADAADAIAEIGDAVF--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007B55C20 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQMVAMNELGQE----- ->[subseq from] Serine hydrolase n=1 Tax=Gordonia alkanivorans TaxID=84096 RepID=A0A3T0UVQ5_9ACTN ---RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD -RGEIDLTSPVTVDPTRWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL -DRVREDLIGLGATSTRIVGGVAELHEAYDAAYSSSSTPRDCTTLLSAVWTDRAASSVMCA -FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTMS -ARPSLPQVDRAIGEVARTVVT-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium baratii TaxID=1561 RepID=UPI0006BABCF9 ------KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE -LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTIFELLVAMLIQSDNTAANKIIDIV-GM -ERINDYLKEMGLKNTVLSRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] Beta-lactamase, putative n=2 Tax=unclassified Clostridium TaxID=2614128 RepID=G7LZR6_9CLOT -------EIKRYLESRIGTYSFFFEDLGSGFTY-GYNENVQMTSAGCMKLPIAVSVIRYVE -DGNASFLDKIKIEEEDKVYGTGILHEFDNREYTVFELLVAMLIQSDNTAANKLIDIV-GM -DRINDDIEAQGLKNTKLNRKTSDERAA-STGVENITSALDLSKIWKHLYDGRFLSEKNSK -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKTS-VENDTALIRTEKG-SFTFTVLSMG -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Planctomycetes bacterium K2D TaxID=2527962 RepID=UPI00118B6677 --------ILDLAQSTPARVGLAVESLDGAWSY-SVLPDEVFAQASAIKVPILWELHRAAA -AGELSLDERLTVDPANGAGGCGMLQNFLPGAMALGDLGVAMIVLSDNVATNLLIDRL-GF -DAVNALLVSQGAKQTRLRRKMIDPEA-RKAGRENTSTPAEAVRLMRRLHDAEGAGDPVAA -AVLKVLRLRKE--SPVTTVLPSDTRLATKPGMLD-GLRTEWSIVEREGV-NYAMALMVDG -GDE--ILIDALVREIAV------ ->[subseq from] Beta-lactamase class A n=2 Tax=Granulicella sp. GAS466 TaxID=2485170 RepID=A0A3N1JWJ2_9BACT ---ALQRELAAIAASHHGRVALYATQLNTGKRV-GLDADTPVQTASVIKLAILFEAMEEVR -AGKARWDEKVTLAKGEAVGGSGVLTLLDTPVLTLKDVLTLMIIMSDNTATNLAIDRF-GV -DAVNARIGWLGLKDTHLYKKIMKPATDQPKFGLGKTTPREMAVVMERIGRCRLAGPGECE -VGLK-MLRNQFYRDTIPRYLETGSGIASKTGSLN-AVRADVAIVAGKTG-PMILSIFTYD -NATADNEGEVTIARLAKAIVEAw ->[subseq from] serine hydrolase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9B36E5 ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVATARAFD -EGSLTATDSVRLVPAQCSPPTGIASFADPVSMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Beta-lactamase n=2 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A0R2G987_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetia bacterium TMED53 TaxID=1986839 RepID=A0A1Z8SC05_9BACT ----LQSQIENRIAQFEGVVGVHYHHLGSGEEI-SIRADETFPTASLVKLPILFALLDRVS -KGELDWHEKRTYKIARRYAGEDLLASFQDGEIALSKLADLMIRYSDNTASLWCQELAGTG -LTINRWLQQNGYPNTYVNSRTPGREDDYKQWGWGQTTPREMTRMVESLYSRECIGSPWDE -LMLKLMNSSYW-REEMLSAFPPEVTVYSKQGAVNR-SRSEVILAMSPSG-PFSLCVITKE -QRDT------------------- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia vulneris TaxID=1141657 RepID=A0A0C1BBT9_9NOCA ------------FRKAGVQGWVHARCFGCAGEN-GLDADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRVRAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL -DNVRSLVRELGLTETRITGAPRDIVQALDPRRSTASTPREMTRLLTLIGQDLAGSAQACQ -WVRDVMREQVN-WYRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPDGSRYAVAVFTRT -ESQRLPEVDRAIGAAAVAAID-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536AR16_9CHLR ---DLVKQLDGLVSSFPGGAGIWIADPTVATPLfAHDAEEQVIAASLYKLGVLAEAERRVD -TGELHYADTVTIEPDDITADGSF--EYAGTELTLDEALEAMITVSDNGAALALWHIL-GG -ANIDATLEKAGISNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISPAASD -RMLARLERQQI-NDRLPAQLPGGVVVAHKTGNLS-GVTHDAGIIYTKTGPRVVVAMTWDA -LD---EDAANFISSIGSLVYS-- ->[subseq from] serine hydrolase n=1 Tax=Sporosarcina koreensis TaxID=334735 RepID=UPI0009E4B35F --tQLEQQLSLLAAGSTGNVSVCVRT--PDGTI-AIGADDVKRSASVLKVPIAMACLAAVD -RGELDLDTRLPIHE--PVGGSGVLAYMSGFTLTLLNAITLSIIVSDNTAANLVIEHT-GL -DRIQAFFDEVGAAGSKLTRKFMDYE-ALALGLENFATARDMVRFLECLDPSKHLSLKSKQ -QLKTIMRDQQL-IDKLPAYQPETLIIGNKTGTLP-GTEHDIAYFEND-RMRVDLAALTTD -WQYN-HDGQQTIARIGRLIIDY- ->[subseq from] serine hydrolase n=1 Tax=Nocardia jejuensis TaxID=328049 RepID=UPI0009FCBBFC ---------DEIFRKAGTRGWVHARCLDCDAEF-GSGADEPVVLSSVVKVPLVLEFARQVA -AGQLDPTDRVRATAADRLGGVATAGCADDVEFSLRDAALLALTVSDNTAADLLFDRV-GV -DNVRSLVRELGLTHTRIAGSQRDILEALDPLRTTASTPRDMTLLLSLIGRDRAAPEQACR -WVRDLMREQFS-GHRLPSGFAADVRTWSKTGTLP-GVRNEIGVVEYPDGSRYAIAVFTAC -DNQRQPEVDHVIGVVARQ----- ->[subseq from] Serine hydrolase n=1 Tax=Williamsia sp. 1135 TaxID=1889262 RepID=A0A1X1AWD4_9NOCA ------QRLREIFADAGCAAWLHARTIGPEREF-GWYADDPVVMASVYKLPLLAALCVRAD -RRDINLRDTVTVDPRECAEPTGIATLHDPITLSWRDLAVQMMVVSDNAAADVILAEV-GL -GGVREILDGAGLHSTHVVAGMAQVQQAYDPALTGATTAREATCLLDLIWTDRVASAGSCD -FIRTTMRKQAW-KQRISSGFPLGATVAGKTGTLG-AIRNEVAVVEYPGEHPVAVAVFTHA -ARLSLPTVEAAIGQAARVAVN-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C2DD0B -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -KNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 14-2496-1d TaxID=2023146 RepID=UPI000B9BBA6F ---TTDEQLRAIFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVATARAFD -EGSLTATDSVRLVPAQCSPPTGIASFADPVSMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR -CMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000931CE10 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIILDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RLI2_9CHLR ---DLVKQLDGLVSSFPGGAGIWIADPTVATPLfAHDAEEQVIAASLYKLGVLAEAERRVD -TGELHYADTVTIEPDDITADGSF--EYAGTELTLDEALEAMITVSDNGAALALWHIL-GG -ANIDATLEKAGISNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISPAASD -RMLARLERQQI-NDRLPAQLPGGVVVAHKTGNLS-GVTHDAGIIYTKTGPRVVVAMTWDA -LD---EDAANFISSIGSLVYS-- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. 8F6 TaxID=2025606 RepID=UPI000B98FBE1 ---ALSQRWAQLAAAQGLQSSAFLLVLDDGRFA-QLQPDLALPAASSIKTPILLAGLEDFD -NGKLRWNEPLPLTKEVVGGGAGWMAKPVGTRFPFFEAATEMIRVSDNSATNLLIKRLGGK -TALNERFTAIGLPSTAVNNWLPDLEGT------NTTSSRDLARSIALVDTGEKLSPRARD -LFREIMGTSRT-NTLIPLGLLLGITAYNKTGDIGI-AYSDAALIQLPNGQRAVAAFMVKG -PFND-PRSADLIRAMAGE----- ->[subseq from] Uncharacterized protein n=1 Tax=Arsenicicoccus sp. oral taxon 190 TaxID=1658671 RepID=A0A0K1FEE8_9MICO -----------------------------GVVA-GWDADREVPAASLVKVLVLVAALREVD -GGRLSLDQTLQLPE-ERVGGSGALSLLPSVTLAVVELLRLMVTLSDNDAANLLLHLL-GH -DRVTRTGREIGLQHTQVARNLRDRAAA-ESGRDNTTTAADQAGLLAALRAGQVLGGASTR -LALALLAEQQH-AYGVTALLPDGVVRGSKPGDLP-GVRHDVALVETGGS-WATVAVTATG -MY-DERH---------------- ->[subseq from] Beta-lactamase class A n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A2N3U4X1_9ACTN -----EDRLAQVFAEAGCQGSVAVLDIDGPGQV-VLGGDELVVAASTFKIAVALELFCRGA -EGELDLAERVRLAPSQATPGQGFCIFEDEAEVSLRDLARMMVTISDNTATDVLIRRV-SV -PRIHARLAALGLDRIRLAGTIQEEFDSLRPGRITSATAGQMAALLRMIWRDEAGPAEACA -AVRSVLGQQRL-TRKIAAGFGDEVRVAAKSGTVPGCVSNDAGVVHFPDGSRFAVAVFTRP -TGPRPPQSDSVMGTVARLGVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Lentzea flaviverrucosa TaxID=200379 RepID=A0A1H9XXB9_9PSEU ---------------AGVEGFVHAREIGDGPEA-GHGADEQVVLASVFKIPVVVAYAAEVA -AGRLDETERTRVTPRYRIGGIGTAGCRDDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ -AAVDAVVA--GLPRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPEACE -RVRAIMAQQIW-PHRLSSGFPADVLVAAKTGTLPS-VRNEAGVVTYPDGRAYAVAVFTRS -QSLDNPSADAVIGRAGRLAVDQ- ->[subseq from] serine hydrolase n=1 Tax=Dyadobacter sp. 32 TaxID=538966 RepID=UPI0011ECFE9A --tKLTRKIEIAMSGFKGSAGVYVRNLKTNRVV-SIHSDSLFPTASMVKIPILCGIFDKIN -RGEIKFAQELVYRDSLKYDNGVVGSFRDSTKIALPKVVHLMISLSDNTGSLWLQALAGGG -ETINQWLDVNGFPNTRVNSRTPGRKQGQAKYGWGQTTPREMAELITMIRNGKAISAEASE -RMYRYLGMQFW-DGEALSQIPPYIKTAAKSGAVNQ-AKSEAVIIHAPHGD-YVLCVTTKN -QESKDNEGYVLIRKISEIVWNHf ->[subseq from] Beta-lactamase class A-like protein n=4 Tax=Candidatus Levybacteria TaxID=1752719 RepID=A0A0G0NSM5_9BACT ---SLRSDVTEYTQKQKGSYSVYYNNFQNNSSF-GIDERQIIVSASVNKTPLIAVLYYLAS -KGEINLDSKITILEKDIQDTGSLRYEKPGGSYSLRNLAKLSLKQSDNTAAHVLGVRI-GM -DKIQKTIDEWGLTQTNMA--------------DNKTSNYDVYLLFRKIYNGEVTNAAHTQ -ELLSFFTDSDF-EDRLPALLPEGTIVYHKTGDAE-GGVHDVGIIKNGENA-YYLGVMTSD -IGEEEGEAKRAIAEISKIIFE-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A162DUM5_LACPN ----VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS -GER--TAQTSAMNDLGQVLYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00071094F4 ----VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS -GER--TAQTSAMNDLGQVLYR-- ->[subseq from] Serine hydrolase n=1 Tax=Actinomadura sp. NEAU-G17 TaxID=2293572 RepID=A0A372JN32_9ACTN -------------AAAGVRGFCFARDIDGDRAV-GVAPDAPVVLASVFKIPIALEYARQAA -AGRLDPTARYAVEPRFRDGGIGTSGCADPVEMSLRDLVLMMLTMSDNAATDVVLERV-GT -DAVNATLTALGRTRTHLVGGCAALLAVCDPARTTRGTARDIAELLAQIWRDEAGPPAACA -EVRAVMARQVW-PHRLASGFDDTHLVAGKTGTLP-GWRNEAGVVQTPGGGRYAVAVFTRS -TRPDHPEADRVIGTVARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI00083AC5F5 --qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRVQPSASIIKVPILLALLEAVA -KGRYALEQPLALPASDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATCLQRRMMDAAA-REAGRDNYTSAGDATAAFCWLLRDDSLPAPLRA -FALDVLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 5K548 TaxID=2530386 RepID=A0A4R5BDC7_9PSEU ------------EWDLPGRVGIASWDLRENAPV-LRGAEVEVHSASTIKVLVMITALRAVA -DGRLDLDAQVELP-ADRTKGTGVLFEVPSVPASLRDLINLMIVVSDNAATNAVIDQV-GF -TAIAECTADLGCTGTRIERHIMDTDA--PGV--LQTTALDQARVLTALAEGTALPPQLTA -HALTVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ -LTD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus alpinitundrae TaxID=468913 RepID=UPI001379599B -------------RGYAGEVGLHISALDGQLLA-THAADVVFPAASIIKVPLLLLALERVQ -AGALNLAERFELRAADRVGGAGVLHELGAGLPSLQDLLTLMIIVSDNTATNLVIEQL-GV -NAVNAWLDERGCSHTRLVGKLEQHNPAQRRGERNRTTAAEQARLLLGLWNGERLDPLHRE -LALSILGHQQY-RDILARPLPHDYRTHTKSGELG-GVHHDVGLLQLPRG--LCVTLLSRG -GS--------------------- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium maritypicum TaxID=300020 RepID=UPI0004CE768B ---ETSAQIAEIFAGAGATGFLHAREIGDGPEV-TVGADEPVVLASVFKILVLTAYVRAVA -AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT -EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Achromobacter insuavis AXX-A TaxID=1003200 RepID=F7SYA9_9BURK ----VDAALAPLLAATPARVSLSLRDLDGGIVL-ARHADRPQPSASIIKIPILLALLEAVA -GGRYTLGQPLVLPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIELL-GF -DEINQWSQRAGLTASRLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGALPAPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] serine hydrolase n=1 Tax=Nocardia seriolae TaxID=37332 RepID=UPI0012BC236A ----------EIFRTAGVEGRVHARCFDCDGEF-GWGADEPVVLSSVVKVPLVLEFARQVA -AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAAYFALTVSDNTAADLLFDRV-GV -DNVRSLVRELGLTRTRVDGSLRDILYAVDPLRTTASTPRDMTRMLLLIGQDLAGVPEACG -WVRDLMRRQVF-GHRLPSGFAPGTDVWSKTGTLP-GIRNEIGVVGYPDGSRYAIAVFTVS -HSGRQPAVDRAIGEAARQAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Microbacterium maritypicum MF109 TaxID=1333857 RepID=T5KJA7_9MICO ---ETSAQIAEIFAGAGATGFLHAREIGDGPEV-TVGADEPVVLASVFKILVLTAYVRAVA -AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT -EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000437A572 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQERYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase n=1 Tax=Mycobacterium haemophilum TaxID=29311 RepID=A0A0I9ZS32_9MYCO ---EVSRQIQAVFTDAGCRGWLQARPVSTVEPAiNFRADEPVPTASIYKVLLLAAVARSFD -RGELDPSARVTIRPTDCTPGPTGFSTFIDPVVSWRDLARSMIVLSDNAAADILLAAV-GL -PRMDEIIDELGLASTHVIGGAAALYEIYDPDQTNATSAADSNTILAAIWTNTIASPHACS -YMRGVLAQQVW-PHRIKSGFPREISVAGKTGTIGK-IRSEVAVISLPNETPIAVSVFTHA -ARHSLPAVDRAIGTAARIAVT-- ->[subseq from] hypothetical protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0006C17615 ----VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMTRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS -GER--TAQTSAMNDLGQVLYR-- ->[subseq from] Uncharacterized protein n=2 Tax=Actinobacteria TaxID=1760 RepID=D9UYN6_9ACTN ----ASETIARRAEEVGVEVRLHAAEVDGNRSL-GIGEDVPVVPASVFKVPIALELARQAA -DGTLDLGARIAVKPGHPTPPYGLATFRHEVLMSWHDLAILMIGISDNVATDLILAEI-GK -DAVNSTLRRLGFTHTVVPQDCAELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA -DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -EDSRVPERDAFIGFAAATAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_O1-9 TaxID=1938856 RepID=A0A3D9W3G7_9ACTN -----EDRLAQVFAEAGCQGSVAVLDIDGPGQV-VLGGDELVVAASTFKIAAALELFCRGA -EGELDLAERVRLAPSQATPGQGFCIFEDEAEVSLRDLARMMVTISDNTATDVLIRRV-SV -PRIHARLAALGLDRIRLAGTIQEEFDSLRPGRITSATAGQMAALLRMIWRDEAGPAEACA -AVRSVLGQQRL-TRKIAAGFGDEVRVAAKSGTVPGCVSNDAGVVHFPDGSRFAVAVFTRP -TGPRPPQSDSVMGTVARLGVE-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. EGI 650086 TaxID=1840409 RepID=UPI00131E55DE ----------------------HARCVGCDHGA-GLRADEPVVLSSVVKVPLVLEFARQVA -AGQLDPADRVRVRAADRLGGTGTAGCADDVEFSLRDAALFALSLSDNTAADLLFDRV-GL -ANVRSLVRELGLANTRIYGSPRDILRALDPRHATASTPRELTRLLQLVWRDEAGPAEACA -QVRALMRQQIN-WYRLTAGFPPEVRVAGKTGTLP-GMRAEIGVAEYPDGGRYAVAVFTRA -DTQRLPHVDRAIGEAALAAV--- ->[subseq from] Serine hydrolase n=1 Tax=Cyanobium sp. NAT70 TaxID=2024872 RepID=A0A2E0AK44_9CYAN --kALSEKWKQLASQHDLQASGYMLVLDDGRFA-QMNAEQPMPAASSIKTPILLAALELVD -SGDLQWNEPLTLTKELVGGGAGWMASPLGSRFPTFEVATEMIRVSDNSATNLLIQRVGGK -TAINDRFKVLDLPATEVNNWLPDLDGT------NTTSAKDLSRSIALVDSGDQLGPRSRD -LFREVMSTSVT-NTLLPTGLLRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVKG -PFND-PRSTNLIRAMASAM---- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Woesebacteria bacterium CG07_land_8_20_14_0_80_44_9 TaxID=1975058 RepID=A0A2M6YFC9_9BACT ----VLTEIENLTKGLRGTYGVYVYQLDGKNEY-GIHQGEIFPAASLMKLPVMLTLYQEAQ -AGQASLETKYKLTEKDKINGAGILQKPVGSTYTYRQLAEFMGQYSDNTANNILVKVL-GQ -EKIQQTISKLGMTKTSFKNY--------------TTTPEDIGIFFRQLYQGGIVNKENQD -EILRFLTKTAF-EDWIPAGLANDIRVAHKIGKDI-GAFSDAGIVF--GRQPFVLVIMSKD -AKES--EVKETLPKITKAVWE-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FF8EFA1 -----THLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000A17A013 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A165RBK9_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A3E2V4D6_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C84ADB -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A0G9GVX1_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] hypothetical protein n=1 Tax=Facklamia sourekii TaxID=87650 RepID=UPI0012ED9C0D -------CFEEAFHSLSGDHSLYYQDLTQADATkLVINSNPMRSASLIKLFILAVFFQQVA -DDQIRLNQTYILQDADKVGGTGTLQQQAEGSYSFLDLAQEMIINSDNTATNILIKQLGGL -SSVQEQINQWDYGDTQLNRYMLDFDA-LASGQDNYTSVEDIANLLRSCYRQELISPVLDR -QMLTILSQQKD-RSKLLARLGHKVKIYGKSGQFQYGVLGDAVIVKQGAK-AYLLIILSQD -GEEQ--DQYPAFNKVGLTVY--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000CE94A8F -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Butyricicoccus sp. 1XD8-22 TaxID=2320083 RepID=A0A658JGY0_9CLOT -----KEELERLIDSVDYNIHLFIKEAKAEDFIfAKKLDEVVSSASLIKVPILIAVLELIE -RQNISLQMEVEIKQNHKVEYSVLTEQDSD-KSKLYELLVWMIITSDNTATNVLIDFL-GM -EECNAFFKKIGLTRTKLQRKMMDFDS-LQKGVDNVTTARDMANLFTRIYKQDLLPLQFSQ -LAIDILSRQRI-NDGLKRYIIENVKIAHK------------------------------- ------------------------ ->[subseq from] Putative beta-lactamase related protein n=1 Tax=Streptomyces sp. Tu6071 TaxID=355249 RepID=F3ZHT7_9ACTN ---------------------VHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARI-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVVPAADAVIGVVGRIVVD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000FF49C4D -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A4Y4GBH5_9MICO ----VERRIAEIFADAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA -EAINRVISDLALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR -QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLS-DRQPLVDASIGRAAF--- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A165NPA4_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000350773E -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000BE3B228 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000B3E499D -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A1C4ZAH6_MICEC -------------ARVGVDARLHAVDVDTGHEV-GVDADEQVVIASVFKILLVLEFARQAA -NGQLDPTERVVVRAGDRLGGWGTAGCADDVELSLRDLAYFAMSVSDNTAADLLMRRV-GP -DLLPLLAAELGLTRTRVIGGPRQLLEVFDPEQTTSSTAREITRLLTMIWRDEAGPPAACA -MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHIEAGVAQYPDGGRYAIAVFART -QRTRRIDVDLAMGEAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=UPI000B84FC48 -------------------GFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA -TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -EKINAGMAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPEAACD -EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL -PGPENPAADAVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0001B00022 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLSLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inyonensis TaxID=47866 RepID=A0A1C6SFK3_9ACTN ---------------VGVDARLHAVDIDTGHEI-GVGADEQVVIASVFKILLVLEFARQAA -DGQLDPTERVVVRAEDRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLMRRV-GP -DLLPLLAAELGLPRTRVIGGPRQLLEVFDPDKTTSSTAREITRLLTLVWRDEAGPPAACA -MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHMEAGVVRYPDGGRYAVAVFAQT -RRLTRIDVDLAMGEAARMAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=bacterium (Candidatus Howlettbacteria) CG_4_10_14_0_8_um_filter_40_9 TaxID=2014279 RepID=A0A2M7RM54_9BACT ---ELLGEINEYLETTPGTYGLYVHELGTDKSF-GINEEMSFPAASTVKIPLLMSLYKDIY -EGKVSKDTVMTYTINDEETGTGIQYTSFGTRWTVSEIAKRMMKQSDNVAKNMIFRLV-GY -RRAQEYITGLGVKGVDMS-------------LENKTTSKDSGTLLKLIYENKTVDKELSD -EMLELMVKTDF-EKRLPRYLE-GVKVSHKIGTWA-GAISDTGIVFLEGR-PYTISVYSEG -IQ-SVDEAEKVIGTISKKVYDY- ->[subseq from] serine hydrolase n=1 Tax=Megasphaera stantonii TaxID=2144175 RepID=UPI001300A395 --------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE -AMRAILAQQED-NCILPAQIPHTVTVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Nitrospinae bacterium TaxID=2026769 RepID=A0A3M1RL20_9BACT --eALVQQLHRLCDSYPFHTGWYLKDLRTGEVA-QRNGDVIVPSASTRKIAIMMAALKAVN -EGKLSLNQPVTIQARYQNNQSGTFQHQPGFTIQFRDALVMMIIVSDNTCTGTIVDML-GL -DYINAFCQSIGMRGTTHRHGIPRLGRHHPVEAVNATTPADVGLLLDLILQGTGCTPALCQ -LGLDILSWQKL-SWRLPAYLPWGTKVAHKTGTGQDGNNNDAGIIFQGEEPLFILSVFTEQ -VPQEMPDG--------------- ->[subseq from] Uncharacterized protein n=1 Tax=Novibacillus thermophilus TaxID=1471761 RepID=A0A1U9K726_9BACL ---ALKENVEQIANSLTGEIAVFIET--SEGTI-AMNETDVMSAASTIKVPILVEAIKQAE -QGDLFWDDEVVVEESDAVGGSGVIKDELPQTFTVRELAELMITVSDNTATNMIMERV-GF -DEVNWACIEMGCVDTVLQTSIYTSMPQ-DRGPHNYSNVKDMVTILKGANEGGFLSPEGRE -EFLSIMRDANQ--ARLSEYQDKDILVGRKGGSTAPRVLHDVGIFTLGDE-HVYAAVFTKD -VQPS--IATPTIGEIGRSIMDY- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum subsp. plantarum TaxID=337330 RepID=A0A2S3U749_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRSADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Predicted protein n=2 Tax=Actinobacteria TaxID=1760 RepID=D9UYN4_9ACTN -----RERIEAVFADAGAEGFLHAREIGPGPDV-SAGGDDPVVLASVFKIPVALAYAREVT -AGRLDDTERTKVTARYRTGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVVYHRL-GQ -ETVDRVLADLGLARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPEACQ -RVRTIMAQQIW-PHRLSSGFPSGVRVAAKTGTLP-GIRNEAGVVTLGDGRQFAVAVFTRA -HSDRLPAVDASIGAAARLAIDH- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces sp. 840.1 TaxID=2485152 RepID=A0A3N1S205_9ACTN -----ERAIRDMFDDAGVRGWLHVADLRRPAARvVIDPGEELPLGSVYKLPLMAAFCRLAD -AGRLDPCHRVTLDAADRVPPTGVSILQDPVTMSLRDLVTLMMTVSDNTAAAAVLRAV-GA -DAVDAVCRLLGMPDTHVRGGVVSTFSVYDPAFKASGTPADLARLLRAVWTDEAASAEGCA -FMREVMRRQPW-THRLASGFPDDVTVYGKTGTFGS-LRHEAGVVELADGSIYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00092FE446 ----VTDLIEQATNGLAGQTSVAVMPLAGSQSV--VVNNHAQRAGSLITLFIMVTAYDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYSEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMTRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANQRLISSKVDH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVRNRQGT-FIMTMMAAS -GER--TAQTSAMNDLGQVLYR-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium neonatale TaxID=137838 RepID=A0A2A7MEL5_9CLOT ---SLEARIEAELISYAGKMCVYVNDF-KGNTI-EIGADEKFETASCIKSFILADLFSQVE -NGTKDLYEKLKYTKKNYINGSGVIQSLDEGVMTAINFAKLMIIVSDNVATNILIDYL-GI -DHINKTIQELGFKDTILHNKI-DFEK---YDKLGTTTPRDYGRLFELIAKKELISEEASN -KMLDIFKMQHY-NSMIVRDFPQYIYVASKSGSMD-ACRNDGGLVFTPYG-PYVIVMFNKE -FHDSNHDATVYGGKVSRMIFDEf ->[subseq from] Uncharacterized protein n=1 Tax=Gordonia namibiensis NBRC 108229 TaxID=1208314 RepID=K6X9E3_9ACTN ---RVDRDVAEILADAGCSGWVHATTIGSPQIEhSFDADAPVVLASVYKLAVLISLCRSAD -RGDIDLASSITVDPTLWAQGPTGLAAFGDPVLSRRDLAISMMTVSDNVAADVLLDEL-GL -DRVRADLVSLGAERTRIVGGVAELHEAYDAAYSSSSTPRDCTALLSAVWTDRAASPEMCA -FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTAR -SEQSLPQVDRAIGEAARTVVT-- ->[subseq from] serine hydrolase n=1 Tax=Muricauda sp. MT-229 TaxID=2597517 RepID=UPI00118F7A61 ----LESRVKGALESFTGKASSVIE--TNNYRI-DFKGHEQLKSASTIKLAVLLEAYRQID -RNLLKPYSIIKMKPEDFTEGSGVLFHLNSVNLSFEDLLTLMIIVSDNTASNIAIRTV-GM -DRVNKLLHDLDCSQTLLGREFMDFGAA-RQGLDNFTSAADLVTMLKAADSDGLLSEDSRR -RVFHILKKQQI-LANLHGRIDEEVSIASKSGNLP-GVVNDAGVFEYRGNK-VYAAVVIND -SP-DNHSGQELIAEIGSYIYD-- ->[subseq from] serine hydrolase n=1 Tax=Desulfofundulus sp. TPOSR TaxID=2714340 RepID=UPI0014085ECD ----LQKQLKDYLAQQPGVYGIYFKDLHSGASF-DINGDEPITAASTVKVPVVLYLNHLVA -QGKLDWDDRVVYDSKDYQGGAGILQFSARDGYSLRVLANLSITISDNIAYRMLVRHL-GK -DNVAQFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSREHPALGE -RLLDDMANPIY-HVGLPGRLPPEVRVAHKEGDVW-GVANDAGIVFAE--HPYILVVLSKG -ET-DVDKGFARIAEISRMVYDY- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia seriolae TaxID=37332 RepID=A0A0B8NGD4_9NOCA -----------IFRTAGVEGRVHARCFDCDGEF-GWGADEPVVLSSVVKVPLVLEFARQVA -AGQLDATDRVRATAADRLGGVGTAGCLDDVEYSLRDAAYFALTVSDNTAADLLFDRV-GV -DNVRSLVRELGLTRTRVDGSLRDILYAVDPLRTTASTPRDMTRMLLLIGQDLAGVPEACG -WVRDLMRRQVF-GHRLPSGFAPGTDVWSKTGTLP-GIRNEIGVVGYPDGSRYAIAVFTVS -HSGRQPAVDRAIGEAARQAVE-- ->[subseq from] Peptidoglycan-binding protein n=1 Tax=Caldanaerobacter subterraneus subsp. yonseiensis KB-1 TaxID=1388761 RepID=U5CV96_CALSX --qELKQNIEKLISQYPGKYGVYFIDLNTGQTF-EINGYDPFIAASTYKVPLNFYLYTLIT -EGKIDPNMKVQYTKVDYEGGAGSIQFEPVGSYTIRELSRRSIVESDNIASNMIMRVV-GR -DNYIKFMENLGAKVIPYS--------------SNIASPYDMSMYMKKLLEYENEHPDTAG -ELMYYLKNTIY-GDRISYPIPDNIEVAHKVGNLDN-VVNDTAIVFHPTK-PYILTILANN -VDSDNSYAYTVIRQISKMVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Vagococcus fessus TaxID=120370 RepID=A0A430A8U8_9ENTE ---ELPDKIVEKVKGLKGYYSYYLHDLSEPSGV--SGSSKKMLSASTIKLFILEKAFAQVK -ADKLELDEPYELLEEDKVPGTGIQNAKEGTTYTTEDLLNLMIVDSDNTATNIIIDRLGGI -EELSDYILDRGYGETTLARKMGDTA-AISEGKDNYTSVDDVGRLMSKLAKKELIGKAEDE -KMLEILSNGKN-HDKLAKHLPDNLTIYCKSGEYDFGVQNDTILVEGPEGD-YILTIMSEG -GDES--EQVSVMQTIGQEAYQ-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000DED33BD -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPSGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A0M7HIH1_9BURK --qHVDAALAPLLAATPARVSLSLRDLDGGVVL-ARQADRAQPSASIIKIPILLALLEAVA -GGRYTLGQPLVLPAADRAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIELL-GF -DEINQWSQRAGLPASRLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGMLPAPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A5F0YB59_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMVRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0006D49AC2 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMVRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Williamsia limnetica TaxID=882452 RepID=A0A318RQT6_9NOCA -----GQRLREIFADAGCAAWLHARTIGPEREF-DWYADDPVVMASVYKLPLFAALCVRAD -NGDIDLREKVTVDPREQAAPTGIAALHDPITLSWRDLAVQMMVVSDNAAADVILAEV-GL -DYVHKVLDEAGLHATHVVGGMAHVQKAYDPALAGATTARDATSLLDLIWTDRVASRHSCD -FIRTTMRKQAW-KQRISSGFPLGATVAGKTGTLG-AIRNEVAVVEYPGEYPVAVAVFTHA -ARLSLPTVEAAIGQAARVAVN-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YJ02_9CHLR ---DLNSALEAAISGIQGDFAWHIEDPSMGRAW-TRNAHEAYPAASTLKVAVFLRLLQLVD -DGRVGLDHQIRLRRWHQVGGAGVLQYFSPETLTVGEVATLMVILSDNTATNMIIDLT-GL -GAVNNLVASLASRVTRINRYYGKPSMALPDGTHAMATANDLATIYREVLAGKILGPIGRQ -AFWQTLLRQQD-RAMAPRHFGPDILIAHKTGAID-GVRNDVGVFWLPES----------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 2131.1 TaxID=1855346 RepID=A0A1H5IQI6_9ACTN ------TALRTAFTDAGVTGRIHALDIGSGAEL-DLYGDELVCTASIHKLPLLVTLHERAA -AGDLDLTEQIDCPPLGRPAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL -DAVNRTAARLGLSRTTVTHSFGEMMAALDPAWGNRSTPRELTRLLAAIWRDEVCTPENGD -AMRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEVGVVEYPDGGQYAVAVFTRT -LSAIVPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Bryocella elongata TaxID=863522 RepID=A0A1H5SZV6_9BACT ----VQAEVEALAASHQGKVGVYLHQLNTDKTV-ALNADEPVQTASVIKLGLLYEAMVEVR -EGKARWDEKITVPANYTVGGSGFLQFFDTPMLTLKDVLSLMVIVSDNSATDLAIDRI-GV -DAVNQRMGQLGLKNTWLYKRIGTMPADQPKFGLGKTTPREMAILMETIG----------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Williamsia sp. D3 TaxID=1313067 RepID=V8D0D7_9NOCA ----------------------------VEREF-DWAADDPVVMASVYKLPLLLALCDLAE -IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL -PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDGTRLLQLIWTDRAVSAQMSE -FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA -ARLSLPTVEAAVGRAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007B5518E -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALY--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL F-3213 TaxID=1463846 RepID=UPI00055E0EB1 -----RERIEAVFADAGAEGFLHAREIGPGPEV-SAGGDDPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDVAHFMLTMSDNAATDVLYHRL-GQ -ETVDRVLSDLGLERTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTERAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -HSDRVPAVDASIGAAARLAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium Gr01-1014_7 TaxID=2017209 RepID=A0A554L178_9BACT ---NLKQVVDNELRGEKGKYGIYIENLKTGETF-AKNEHESFEAGSLYKLWLLGAVFEKIK -DGTLKEDEILSGDIADLNTKFDIASDELTEGLTVKDAIEQMITISHNYSALLLTSKM-GS -SKINDFILKYGFNESSPGPP-------------VKTTASDMARFFEELYAGRIIDKESSE -KMLEILSRQQV-RDRITKNLPGGVRVAHKTADIGF-FEHDVGIVFTPKGD-YVIVVLTET -DSP--EKTAQKIAEISKAVYEYf ->[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus marinus TaxID=1219 RepID=A0A163QTV0_PROMR ----LSNRWRDLAKQQDLQASAFLLVLDDGRYA-ELSAETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -NVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYSDAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces kasugaensis TaxID=1946 RepID=A0A4Q9I040_STRKA ---TAEARIQEAFDAAGVRGYFFAREIDGDRTL-GVAADEPVCLASVFKIPVALAYAREAA -AGRLVRTERLAVDPHYRDGGIGTAGCADPVEMSLRDLVHMMLTMSDNAATDVVLERV-GL -DTVNGLLRELGRDRTHLVGGCLELTGVCVPERTTRGTARDIAELLAQIWRDEAGPAEACA -EVREVMSHQIW-PHRIGAGFDDGYRLAGKTGTLP-GWRNEAGVVEHTDGGRWAVSVFTWS -RTPDNPAADRVIGTVARLAVDE- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000CDE0C1E -----TDLVAQSTNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis circi TaxID=871959 RepID=UPI000E25BDD3 -----REQIEAVFADAGAEGFLHAREIGQGPEV-SAGGDDPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ -ETVDRVLADLGLARTRLIGCCEDLFAVRDPERTTSSTPREITTLLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVAIAAKTGTLP-GIRNEAGAVTLGDGRRFAVAVFTRA -HSDRLPAVDASIGAAARLALDH- ->[subseq from] serine hydrolase n=1 Tax=Nocardia vinacea TaxID=96468 RepID=UPI0002EFAE07 ---------EEIFRKAGVRGWVHARCLDCAGEV-GLGADEPVVLASVVKVPLVLEFARQVV -AGQLDPTDRVRASAADRLGGVGTAGCLDDVEFSLRDAAFFALTVSDNTAADLLFDRV-GL -DNVRSLVRELGLTETRIVGSPRYVVQAMDPLRTTASTPRDMTRLLTLLGQDRAGDPAACR -WVRELMGQQLN-WHRLAAAFPSEVSVWGKTGSLP-AIRNEIGVVAYPGGSRYAVAVFTRA -DTQRLPEVEHAIGEAARLAIH-- ->[subseq from] serine hydrolase n=1 Tax=Williamsia sp. D3 TaxID=1313067 RepID=UPI00068592F8 ----------------------------VEREF-DWAADDPVVMASVYKLPLLLALCDLAE -IGQIDLTATVVVDPADWAVPTGIATLHDPVTLSWRDLAVQMMVISDNAAADVILDRV-GL -PRVQEKLDALGLTETRVVGGMAELQQAYDPALASATTPRDGTRLLQLIWTDRAVSAQMSE -FVRSTMRKQAW-QQRLSSGFPLGVTIAGKTGTLG-AIRNEIAVVEYPGEHPIAVAVFTLA -ARLSLPTVEAAVGRAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Mycolicibacterium canariasense TaxID=228230 RepID=UPI000A158400 ------------------------------------------------------------- ------------------------------------------------------------P -SAITEFARSIGDNETRLDRWETELNSATPGDARDTSTPQALGDGNRALLEGTALTLESRR -QLIEWMVANST--SSLRPGMPPEWILADKTGSGGYGSTNDVGLGFGPGGQQVVLSVMMRS -ATPNADGFRPVMTEIAAVAM--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=UPI00101E787B -----------------------------DGEI-AIGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL -DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACT -QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS -REASRTEVDAAIGATARVAVD-- ->[subseq from] Uncharacterized protein n=3 Tax=Gordonia TaxID=2053 RepID=F9VW03_9ACTN ---RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD -RGEIDLTSPVTVDPTRWAQPTGLATLRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL -DRVREDLIGLGATSTRIVGGVAELHEAYDAAYTSSSTPRDCSTVLTAVWTDRAASAEMCA -FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTRS -ARPALPQVDRAIGELARTVVT-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) TaxID=580327 RepID=D9TSS5_THETC --qELKNNIETLLSQHPGKYGVYFIDLNSGETF-DINGYDSFVAASTYKVPLNFYLYTLIT -EGKIDPNMEVQYTSQDYESGSGSIQYDPVGTYTIRELSRRSIEESDNIASNMIMRVV-GY -DNYLNFMKSMGANVIPY--------------TSNITSPRDLSLYMENLLNYVNAHSGTAG -ELLNYLENTIY-NDRISYPLPSNITVAHKIGNLSD-VVNDTAIVFYPSK-PYILTVMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Shapirobacteria bacterium CG10_big_fil_rev_8_21_14_0_10_40_9 TaxID=1974888 RepID=A0A2M8L3C2_9BACT ------TEIENLTKGLRGNYGVXXXQLDGKNEY-GIHQVEIFPATSLMKLPVMLTLYQEAQ -AGQTSLETKYKLTEKDKIIGAGILQSKPTGSYTYRQLAEFMGQYSDNTANNVLVKVL-GP -EKIQQTISNLGMTKTSFKNY--------------TTTPEDIGIFFRQLYQGGVVNNQHRD -EILRFLTKTAF-EEWIPAGVPKDIRVAHKIGKDI-GTFSDGGIIFAE--KPFVLVIMSKD -AKES--EAKEVLAKITQVV---- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 14-2483-1-1 TaxID=2023148 RepID=UPI000B9A4FB2 ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDYEGDEPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL -DSLATVIEDLGLEQTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASQAQCR -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEKPVAVSVFTRA -ARMDLPLVDQAIGSAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium amazonitimonense TaxID=1499689 RepID=UPI00050995D2 -------EIKKYLESRIGQHSFYFEDLEGGYVY-GYNENVQMISAGCMKLPIAIAILKEAE -NGKFDLKDKVTVFREDKVSGTGIIHEFGEREYNLSELLIAMLIQSDNTAANKLIDMI-GM -PRINELFQEMSLKNTVINRKILEEK-DVKNVVQNITSSYDLCLCWKHLYKHSYLNEEHSK -MVIDILKRQQM-KNKVAFYIPEDIKMANKTGDLS-GVENDTALIQISKGN-FAFTVMSQG -IPN-NVYGNITLAKCGKMMWD-- ->[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus marinus TaxID=1219 RepID=A0A163WTM1_PROMR ---TLSNRWRELAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI0013014C05 ---------------------------QTHETL-TRDPDQVMETASVIKLPIMAATFQYLA -DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQF-GI -PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATARELGMILTQLYHRTLVNKDASD -VMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH -SRHIDNEALVILPQLSRIIFDYf ->[subseq from] Uncharacterized protein n=1 Tax=bacterium SCGC AG-212-C10 TaxID=1799370 RepID=A0A177PVW2_9BACT ---RLHSAILDAVAGAGGSTSVVVLRLGDGLAA-EVDGDGQYYAASLFKLAILYEAERRIS -LGEFSLDSPVLYTAEAFAETVGSLS-FSDDGIPLGDALAAMVEISDNSSAIAIVRML-GP -GTVDETMRSLGLEVTSVNTTELP------------TTARDMARLMQAIVNGEGVTETQRQ -HMRQLLLGQHT-RDGIPAGLPEGIVSGNKTGTWD-GATHDVAFVDAPGGE-YVIAVLTDR -GW-----DWPTIANVSAAVY--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561WCB5_9ACTN ----AEQRVEEIFARAGGSLHVVGVDGPAGREV-AVRADEQTPIASVFKILLVLEFARQVA -AGQLDASERVLVRADDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELDLPRTRILGGPRQLVEVFDPAHTTSSTPREITRLLGLIWRDEAGPAPACA -TVRELMSRQLF-WTRLASGFPAGVRVAAKTGTLP-GLHLEAGVAEYPDGSRYALAVFART -DRTRRIDVDLAMGEAARTAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8JJU3_9BACT ----------------SGRLGVSALLFDRRAHI-GFNEDDRFPMASVVKVPIGMLIACEIA -NRTLSVDEKIRIHSRTASPGNPLDRFYFPFEHTVDQLMAFMLHHSDNTATDAILHRLGGI -GALTNFLRDLQIEGISIKRTMHELLTHLIRTGEETCTPRAMAQLLKLLTLNS-----KYA -LVYSHMQRCATNKRRIAEGLKEQKSFGHKTGSLG-AIANDVGILHLKNGYFAALAVMTCH -SAVRMPVRDNEIATVTRAVIGQw ->[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1N5G7_9ACTN -------VLSDIFEHAEAEGFVHARDLDSGAEF-GYRADDRVVLASVFKIPIALEYARQAA -ASDLDPAARHTVTAAYRSGGSATDGCAYDVEMSARDLAFMMMTISDNAATDLLLDIV-GI -ERVRALLDGLGFPGFGVSS-CRALDDVNDPARSPSSTPREVTALLAAIWRDEAGPGRACA -EARDIMGQQVW-QHRLVSGFPSRVRLAGKTGTDF-AIRNEAGVVQYPDGKRYAVGVFLRT -SRDRQPRADRAIGLAARAVIDH- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429DXV4_9PSEU ---DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ -ETICRVVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSAGFPSDVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA -HSGRLPEVDASIGAAARLALDH- ->[subseq from] Beta-lactamase n=1 Tax=Crocosphaera watsonii WH 0401 TaxID=555881 RepID=T2J8W3_CROWT ------------------------------------------------------------- ------------------------------NKFTALEVARKMIVISDNTATEMLVKQMGGK -EVLNKRFKEWGMKNTEINNILPDLEGT------NKTSSEDLSKLLARIERGDLISARSRD -RLIDIMEGTRT-RTLLPQGLEKQANIAHKTGDIGT-IIGDAGIIDMPTGKRYIGAVFAER -AYND-VAGRHLIQDISRTVYQHf ->[subseq from] Secreted beta-lactamase n=2 Tax=Streptomyces TaxID=1883 RepID=D5ZPI6_STRV1 ------------------------------REV-AVGADDPVVIASIFKVLLVLEFARQVV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GP -DTVRLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWSDAAGPPEACA -FVRDLMSRQVF-RHRLASGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -RDVSRATVDAAIGRAAGI----- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces albidoflavus TaxID=1886 RepID=A0A2A2ULN5_9ACTN -----------------------------DGEI-AIGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL -DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACS -QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS -REASRTEVDAAIGATARVAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Gluconacetobacter liquefaciens TaxID=89584 RepID=A0A370GB20_GLULI ---AMADAVARLTAGQPGEFAVYAAPSGQAPDV-CLHCDEPINAASTIKLLVLDAAYAAFR -DGTLKPDEAIIVHNRSLVGGSFSLYAEAGRPVTVIELLRVMIQYSSNLATNLMVERL-GV -IQIRGVVAQQGLEGITFGRMIEDFDAD-AKGIRNRVTARGLGGFLQKLDHGAIVGPAESR -AMIGIMLGQTF-NDLIPPGLPGGTLVAHKTGWVN-GVRNDAAIVFLPNGAHYILVELSRD -LP-DEAAGIKVLNAISSTVFKAy ->[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI0011DE4DF4 ------KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVSMTAAGCMKLPIAVSLIKAVE -DKKVDFMDKIKIQTSDKVYGTGIIHEFNEREYTVFELMVIMLIQSDNTAANKIIDIV-GM -EQINEDIIAMGLKNTRLNRKTNDERTD-ITDIENITTAYDLSKIWKHLSNGTFLSKDNGQ -MLIDILRRQQI-KNKLALYIPDDIEISSKTGDKK-GVENDTAYLELPKGK-FVFTVLSQD -IPNS-VYGTVSLAKCGKMMW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharopolyspora dendranthemae TaxID=1181886 RepID=A0A561UA24_9PSEU --------------ELPGRVGIASWDLRENAPV-LRGAEVEVHSASTIKVLVMITALRAVA -DGRSNLDELVPLPPER-TRGTGVLFEMPSVPISLRDLINLMIVVSDNAATNAVIDQV-GF -RAIAECTSDLGCTGTRIERHIMDTEA--PGVLR--TTALDQARVLAALAEGEALPPELAE -HALAVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ -LTDP------------------- ->[subseq from] Serine hydrolase n=1 Tax=Bacillus circulans TaxID=1397 RepID=A0A3G4ZD51_BACCI --eKLSKRIDKIVQEYEGHLGIAIEW--KEQSF-LLNENDIFPSASLIKLPVLIEGFMQSS -SGILDLEDLVKVNSLQKTGGAGIVQYMSPQSLSIRDLLTLMIIVSDNMATNYLIERL-GM -DNVNKRCQQIGMSSTILQRKMMDRE-ARERKIENYTSPQDILRCLKSIYNDKNQSEK--- ----TILDHQQL-LDKLPYYHRSGIRIANKTGELDK-VEHDCAIIEHEDET-IFIAVLTDQ -LTAN-QKGKEIIQLIGASIFE-- ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DE292B ---TLEKRIAAELYSYQGKMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSKEASA -AMLGIFRQQHY-NTMLTHDFPQFLWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. Bac332 TaxID=2419842 RepID=UPI000EF50294 -----------------DHFSVYIET--NEGTI-SINPAQLRCAASLAKLPILIAGFRQLD -KNPHLQDKLVYIKRENMVGGAGVINYLSHSHYSYRNLLELMIIVSDNTAANVLLDIL-GV -ETINQLTKDADCQQSIIQRKFMDLQAK-ENGLDNYTSAYDIAKLLHLISENKFLTKESQK -MILTILANQQF-TNKLPSYLQDEIQFYHKTGELQ-GVTHDAGIMKYQDKT-IHVVLLSEG -IS-LNAESERIIADIGHLLIR-- ->[subseq from] Serine hydrolase n=1 Tax=Desulfofundulus salinum TaxID=2419843 RepID=A0A494WY98_9FIRM --qPLQEQLKDYLAQQPGVYGIYFKDLHSGASF-DINGDEPITAASTVKVPVVLYLNHLVA -QGKLNWDDRVVYDSKDYQGGAGILQFSARDGYSLRVLANLSITISDNIAYRMLVRHL-GK -DNVARFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSREHPALGE -RLLDDMANPIY-HVGLPGKLPPEVRVAHKEGDVW-GVANDAGIVFAE--HPYILVVLSRG -ET-DVDKGFARIAEISRMVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC723 TaxID=2530381 RepID=A0A4V2XBA1_9ACTN ----VRQRIRDIFARAGGSVHVVPVDGPDGREV-AVEADRQSVIASVFKILLVLEFARQAA -AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAYLTMSVSDNTAAELLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEVFDPERTTSSTARELTRLLSLIWRDQAGPAAACA -TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGSRYAMAVLVRT -ERLA-T----------------- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI0003AAE8E9 ----IQAQIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ -ETIDGVLADLGLARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPQACE -RVRTIMAQQIW-PHRLSSGFPSGVRVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -HSDRLPAVDASIGAAARLAIDH- ->[subseq from] serine hydrolase n=1 Tax=Synechococcus sp. N19 TaxID=2575512 RepID=UPI000E0FAA29 ---------ELAAQQRDLQASAYMLILDDGRFA-AMQAERPMAAASSIKTPILLAVLELLD -QGTLQWNEPLTLTEELVGGGAGWMASWPGSRFPTHEVATEMIRVSDNSATNLMIARAGGM -DAINARFQELDLPSTVVNNWLPDLDGT------NTTSARDLSRAIALVDSGELLAPRSRD -LFREVMGTSIT-NTLLPRGLMRGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVEG -PFND-PRSTELIRQLVAA----- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. ISID311 TaxID=2601673 RepID=A0A5C6WGV9_9ACTN ----TQDHIRTAFADAAVTGWLHACDIDSGAEV-AFHPDHPVVTASVHKLCLLVALHQCAA -QGDFELTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL -DAVNRTTTQLGLSHTLAIHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHSA -AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia amikacinitolerans TaxID=756689 RepID=A0A285KTK6_9NOCA -----EERIREIFAELPVRGRFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD -AGQLDPTERVLVRAVDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP -DTPALLAAELGLGATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWRDEAGSPAACA -ATRDLLRRQMF-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS -DETRRIDVDLAMARSARLAV--- ->[subseq from] Beta-lactamase n=1 Tax=Acetobacter indonesiensis 5H-1 TaxID=1231340 RepID=A0A0D6NG42_9PROT ----LAHQIEKTVLGQKGLFAVYAARVGARPEV-CQNCDHLINAASTIKLFVLDAAYKAFA -SGTLHPTDLIPVHNHSLVGGTFVLYAQQGKEVPVSELLRVMIQYSSNLATNLMIEKL-GV -FPIRDVVKEQALDGIVFGRMIEDFDAD-AQNIRNRVSARGLGEFLQKLDQGQIVGKEASQ -SMITIMLGQKF-NDIIPPGLPAGTPVAHKTGWVN-GVKNDAAIITLPDGSHYILVVLTSG -LP-DEAAGVKILNIISQEVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Megasphaera stantonii TaxID=2144175 RepID=A0A346AYD2_9FIRM --------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE -AMRAILAQQED-NCILPAQIPHTVTVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831) TaxID=221109 RepID=Q8ELZ1_OCEIH ---------------------VSIIVKTNNGII-RSKETKQMRSASIIKLFILASAYHLKE -KGKISLTDQIKLSSNDFVQGSGVISYLSDVKLTYQQLLELMIIVSDNTASNYLIERL-GI -PEIQAFIENLGCQQTRLERKFMDIEAQ-KLGKENVTSALDVIRLFDIFTENNFLGEKSQQ -HILSILKNQQF-NSKLTAYTEPLVTSYHKSGELK-GVEHDAAIFLKDNK-SFKVVVLTEG -WE-NNGDGQAFIASFGKVL---- ->[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium KBS 146 TaxID=639030 RepID=UPI0006919E3F --qSLQQKLAALAATHKGHVTLYATQLNTGKTV-ALDADRPIQTASVIKLAILYEAMEQVR -EGKAHWEEKLTLAKGDGVNGSGVLTFFDTPLVTLKDVLTMMVIVSDNTATNLAIDRF-GV -GTINARIAWMGLNSTHLYKKIESMPADQPKFGLGKTTAHEMETIMERIGRGEPAQPGDTA -ICQTTMLRNQFYRNTIPRYLETGSGIASKTGSLN-AVRNDVAIVAGKSG-PIVISIFTDG -NQTADNEAEIIIARLAKEIVEAw ->[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium TAA 166 TaxID=278963 RepID=UPI0006942E21 --qALEQRLQSLAATHRGHVSLYATQLKSGKTV-ALNADRPVQTASVIKLTILFEAMEQVR -AGKARWDEKLTLAKGDGVSGSGVLTFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRF-GV -DAVNERIAWLGLKDTHLYKKIGKPATDQPKFGLGKTTAHEMEIVMERIGRERAADAAICQ -TAL-TMLRNQFYRNTIPRYLETGSGIASKTGGLN-AVRNDVAIVAGKSG-PMVISIFTTE -NETPDNEAEMMIARLAKEIMMAw ->[subseq from] Serine hydrolase n=2 Tax=Clostridium TaxID=1485 RepID=A0A2A7MKC5_9CLOT -------EIKRYLETRIGTYAFFFEDLESGYSF-GYNENVQMTSAGCMKLPIAMSVIKYVE -KGKASFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI -DNINEDIDAMGLKNTKLNRKTSDERAA-SSGIENITSALDLSKVWKHLYNSTFLNEKDSI -MLADILQRQQM-KNKLALYIPDDYDISSKTGDKS-GVENDTALIHLQKGT-YTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=A0A1F4UV06_9BACT ---NLNKQIDIQLKKLGGDAALMIKFLNTKEEI-KVNQEFQFWAASVIKIPISCEFFRQVN -EGKIKPETKTKIKAENRVEGSGVFKLLNKDDFTYLDLVTLMLDISDNAGTNEIVDII-GW -ENVEKYMHQLGLLNTTFRHKMMI--K--AGRGPNFTTAQDITMLLEKLYNNEI---PGAT -QILTILKQQQD-RRRIPLLLPNDIEISNKTGSLEK-AVHDAGIIYTKNP---FIFVFLSD -DQEDKILTNEVLSNCAKLCFDY- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI000C2605B6 --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Nocardia bhagyanarayanae TaxID=1215925 RepID=UPI001153A9A4 -----EERIREIFAELPVRGRFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD -AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP -DTPALLAAELGLAATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWGDEAGSPAACA -ATRDLLRRQIS-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS -DETRRIDVDLAMARSARLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A562DAA8_MICEC -------------ARVGVDARLHAVDIDTGHEV-GVDADEQVVIASVFKILLVLEFARQAA -NGQLDPTERVVVRAGDRLGGWGTAGCADDVELSLRDLAYFAMSVSDNTAADLLMRRV-GP -DLLPLLAAELGLTRTRVIGGPRQLLEVFDPKQTTSSTAREITRLLTMIWRDEAGPPAACA -MVRDLMSRQLF-WTRLPSGFPPDVPVAAKTGTLP-GLHIEAGVAQYPDGGRYAIAVFART -RRTRRIDVDLAMGEAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Catellatospora paridis TaxID=1617086 RepID=UPI0012D39836 -----TNRIADLFAGADMQGWLHARDLDTGREV-AVGADDQVVIGSIFKILLVLEFARQTA -AGSLDPADRMLVRAADRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRV-GP -DLLPLLAQELGLARTRLVGGPREILEVFDPGHTNSSTPEEITRLLGLIWRDEAGPAQACA -TVRELMFRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAKT -ERLSMPELDLVLGRAAKLAV--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aquimaris TaxID=189382 RepID=UPI0009DF09AC ----LERQIHELVEGVEGRISLNIEL--PAHTI-QLHSDVPYSAASLIKLPILLEGYRQIQ -ERKLDPEEVIPVTQEDKVGGAGVLSHLSPHTVTVHDLLTLMIIVSDNTASNLLIDRM-GM -DSINGMCRLLGLEQTKLNRRLMDFE-ALESGVDNHISATDAVKCLKGMENEVLFQLSCRE -SMIRILQNQQF-YQKLPGSMDNRVFTANKTGELP-GVEHDCAIIRYNQK-TVYAAVLIDE -LK-DGSEGSGLIMKVGKCLND-- ->[subseq from] serine hydrolase n=1 Tax=Agaribacter marinus TaxID=1431249 RepID=UPI0013ACF1DD -----------------DHFSVYIET--DEGTI-SINPAQLRCAASLAKLPILIAGFRQLD -KNPHLQDKLVYIKRENMVGGAGVINYLSHSHYSYRNLLELMIIVSDNTAANVLLDIL-GV -ETINQLTKDADCQQSIIQRKFMDLQAK-ENGLDNYTSAYDIAKLLHLISENKFLTKESQK -MILTILANQQF-TNKLPSYLQDEIQFYHKTGELQ-GVTHDAGIMKYQDKT-IHVVLLSEG -IS-LNAESERIIADIGHLLIR-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia stercoris TaxID=2483361 RepID=A0A3M2LH60_9NOCA ----------TIFRAAGAQGWVHARCLECAAEV-GSGADEPVVLASVVKVLLVLEFARQVA -AEQLDPTDRVRISAADRLGGVGTAGFFDDAEISLRDAAFMAITVSDNTAADLLFDRV-GV -ANVRSLVTELGLTRTRVLGAPRDLHTATDPLRTTASTPRDMTRLLALIDQDRAAPPDACS -WVRELMRRQVY-THRLASGFRPGTRIWSKTGSLP-GFRNEVGVVEDSDGFRCAVAVFTKV -DSVRMPMVDRAIGAVARAAVD-- ->[subseq from] serine hydrolase n=1 Tax=Jiangella sp. KE2-3 TaxID=1623398 RepID=UPI000E34CE20 ----------------GVTGFLHATDLASGAEA-GVDPDAPVVTASVFKIPVLVELCRQFA -AGERAHTDRMRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -ERINAGMAALGLPGTVLEEDCAGLFRVLDPETTNRSTPRETTTLLRRIWTADGLPEQACA -EARRIMGLQVW-PHRLTSGFPDDVKVSGKTGTLSH-VRNEVGVVEYPDGAAYAVAVFLRL -PGPANPAADAVIGTAARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Kitasatospora aureofaciens TaxID=1894 RepID=A0A1E7N7P8_KITAU -------------AEAGVTGLLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA -AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL -DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATSLPTADAAIGTAARLAVD-- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Prochlorococcus TaxID=2627481 RepID=A0A162CFT3_9PROC ----LSNRWRDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] Class A beta-lactamase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A1D8IGR0_9BURK --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA -NGRHALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRADLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2W1AN95_9CHLR --nSLQSSISDIIEGFSGIASVSANNLTSGDVL-SINETKILPALSTIKIGIMAELFFQIQ -EGKFKLTDRVTVQSSDIRGGTGVFRELQTPFVTIKDLCMMMIVVSDNTCTWMLCTRL-GK -DAINQRMRSIGMNEFSLNHDLQDMQGK-DVDAYSECSARDFTKLVTLMANGELVSKQASN -EMLDIMGRCQH-IEWLGRYLPPKVKLYNKVGAYLH-ARCDTGLIKSEKS-NYVITVFASY -SKDEPHEGSELIGKVSKVVYDAw ->[subseq from] Beta-lactamase n=1 Tax=Clostridium baratii TaxID=1561 RepID=A0A174S360_9CLOT ------KEIKKYLESRIGTYGFFFEDLNSGFVY-GYNENVQMVAAGCMKLPVAMALIKDVE -LGKVTFMDKIRIDGADKVYGTGIIHEFDARDYTTFELLVAMLIQSDNTAANKIIDII-GM -ERINDYLKEMGLKNTVLNRKTADERKE-KPKVENLTTAKDLSMAWKILYDATFLSKENST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKP-GVENDTALIQLSKG-SFTFTVLSMS -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A659B9A0_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYSKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. CFHS0054 TaxID=2382165 RepID=A0A386ZJA1_9NOCA -------------------GRVHARCVDCAGEF-GWGADEPVVLSSVVKVPLVLEFARQVA -AGQLDATDRVRATAATRLGGVGTAGCLDDVEYSLRDAARFALTISDNTAADLLFDRV-GV -ENVRSLVRELGLTRTRIVGSLRDILYAVDPLRTTASTAREMTSLLAAIATDRAAGPEVCG -WVRDLMRQQVF-GNRLPSGFPPGTDIWSKTGTMP-GIRNEIGVVGYPDGSRCAVAVFTVS -QLGRQPAVDRAIGEAARTAVE-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Tsukamurella paurometabola TaxID=2061 RepID=A0A3P8MDF9_TSUPA -----AERIDAVFADAGCNGWLHARVVGHPAAL-SVRGAQAVVPASVYKVVLLVAAARAVD -AGRLDPRARITVDPAVSTPPTGIATLSDPVEMSVRDLLRSMVAVSDNAAAGVLMRLV-GL -AAVQEAARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDTAASAEQCA -FARSALAGQVF-RHRIASGFGSAPSIAGKTGTLG-ALRNEVAVVTYPGEHPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium paraputrificum TaxID=29363 RepID=UPI0012D28E49 ------KEIKRYLESRIGTYGFFFEDLSSGFIY-GYNENVQMVAAGCMKLPIAVSLIKAVE -DKKVDFMDKISIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM -DNINSDIKEMGLKNTILNRKTSDER-QPKDGIENITSAYDLSKIWKHLHNATYLNRDNST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLPKGN-FVFTVLSTS -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptacidiphilus sp. DSM 106435 TaxID=2126346 RepID=A0A345SX97_9ACTN --------------------------------V-GIGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVLVTAEDRLGGWGTAGCLDDVELSLRDLAHFTMSVSDNSAADLLMARV-GV -DTVRLLARELGLDRTRIVGGPREVLRALDPLRTNASTPREITRLLGLVWRDEAGPPEACA -QVRDLMGSQVF-RHRLISGFPDEVVVAAKTGTLP-GLHIEAGVVHYPDGGRYAVAVFART -LDTGRAQVDAAIGTAARIAVEY- ->[subseq from] Putative beta-lactamase n=1 Tax=Prochlorococcus marinus (strain MIT 9303) TaxID=59922 RepID=A2C838_PROM3 ---TLSNRWKDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. Wb2n-11 TaxID=1030533 RepID=UPI000A409244 ------------------------------DEV-AVDADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLAQV-GL -DTVRLLAEELRLDGTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLVWRDEAGPPDACA -QVRELMARQVF-RHRLVSGFPDEVTIAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -REASRPAVDAAIGAAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Arthrobacter sp. GMC3 TaxID=2058894 RepID=UPI000CE3956D ------DQLADIFTAAGATGFVHAREIGDGPTV-SLNPDEPVVLASVFKVPFAVAYSREVS -AGRLEQTGRTTVTPRYRVGGLGTAGCDDDVEMSWRDLAKFMMTMSDNAATDVVFHRI-GQ -AAVDAVLDDLKLKHTTIIGCGEDMDIILDPARTPSSTPRDIVTLLDAIWTNAAGSVETCE -RVRSMMAQQIW-RHRMATGFDGNVLVAGKTGTLP-AIRNEVGVVTYPDGRHYAVAVFTKA -ATDPQPAIDASIGKAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus misasensis TaxID=392413 RepID=UPI000A03647D -------CLAELVLRFDGEVSLCVSDLQGELLF-VHEEHRVFKAASLIKLPILSCALEQVQ -QNGLSLQDRLAVSRENQVPGAGVLHEMETGLLTVQDLLTLMVVISDNTATNVLIEAL-GI -HTINQHIERIGLKNTFLVGKLEGQNEQQKAGQRSTTSAADMNLWLHKLVHTELLNPELGG -WATNVLKRQQD-RNVIARRLPRTFDVASKSGEISL-HRHDVGIVYAA--RPYVVCLLSRG -SKD-------------------- ->[subseq from] Beta-lactamase n=1 Tax=Prochlorococcus sp. MIT 0701 TaxID=1499502 RepID=A0A0A2CM72_9PROC ---KLSNRWRDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] Beta-lactamase class A n=1 Tax=Microgenomates group bacterium GW2011_GWA2_44_7 TaxID=1618500 RepID=A0A0G1JN84_9BACT ------EELGKLLSTYTGTYGVFVEDLQSGFSY-GVKEDEEFPAASQMKLPIILAVYLEYE -KGNLNLDAPYTLLKSDKIEGTSLASFKDGSNFTYRKLIEFSARNSDNSAIRILWRKL-GN -ERIRESLIVGGMKNSSFE--------------NDITTPKDIGNFFSLLYRDMLLRKEQKE -ELIGFLTNTIS-EDRIPAGLPAGTRVSHKIGTED-GAYSDSGIIFG--KKPFILVVMSKG -AN--FKEAPSAIAKIAQTVWS-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces vitaminophilus TaxID=76728 RepID=A0A0T6LWY3_9ACTN -----RARIREVFASAGVTGWLHATEVDGVHDV-AVDADTPVCTASVHKLCLAVTVQRLAD -EGRLDPREQVEVPAAGRTPGTTGLSVMQDPVMSLRDLLLLALTVSDNAAAQVLFERV-GL -EEVNRTTRSLGMRRTVAVHTPRDLVEVLDPARTSRSTPREMTSLLAALWRDEACSAGRAQ -ELREALALQVW-PHRLASGFPDDVRVAGKTGTLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ARANQPAADAAIGTAARMAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Gordonia westfalica TaxID=158898 RepID=A0A1H2KNP3_9ACTN --eQVDSDVTEILADAGCSGWLHATTIGSPQIShSYDADAPVVLASVYKLAVLISLCRSAD -RRDIDLAASITVDPTQWAQPTGLAALRDPVTLSRRDLATSMMTVSDNVAADVLLDEI-GL -DRVRDDLLDLGLRNTRIVGGVAELHEAYDAAYSSSSTPRDCTTLLTSVWTDRAASNEMCA -FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEIGVIEFPGELPVAVAVFTMS -ARSDLPHVDRAIGEAARTVVT-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. Leaf278 TaxID=1736319 RepID=A0A0Q6KIK8_9NOCA ---TTDEQLRAAFADAGCRGWVRAERIDGTGTVvDYEGDDPVVAASVWKIVLLVAAARAFD -DGSLTATDSVRLVPAQCSPPTGIASLADPVTMSWRDIARSMITVSDNAAADALLGAL-GL -DALTAVIEDLRLDQTRIVGGTKTLGEGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCR -YMKQVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEEPVAVSVFTRA -ARMDLPLVDRAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=UPI0012DF6D05 ---TLEKRIAAELYSYQGKMSVFVDDL-RGSTV-EIGADEEFETASTIKAFILAVLYLQAS -RGRADLEEEITYEASQFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMIIDYL-GL -DTINACIRELGFGHTVLHNPLH-FD---RYDKLGTTTPRDYAALFAQVAKGTLVSREASA -AMLGIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKE -FHD-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2WYW3_9ACTN --------IQQCFEDAGVWGWLHAVDLHDDREV-GFFPDEQVALASVFKLPLLAAYARMVD -AGEIDPVATVTLDPSRRTPGSTGFAAMADPIVSWRDLARSMITVSDNAAADELLDAV-GL -DRVRALLDDLGLRRTRITGGSRDLFDDPENPHSSVGTCRDMTRLLMAIWRDRAASPDQCV -YMRTVLTQQIW-TQRLAAAFPDDVVVAGKTGTFI-ALRHEVGVVEYPNGETYAVAVFTRS -PRTRLPAADAAIAQAAKIAVA-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI0010F7E339 ----IEKRIAEVFAAADAEGRLHAVDIDPGRQL-GLGVDDQVVIASVFKILLVLEFARQAG -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDARHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RRRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Gordonia namibiensis TaxID=168480 RepID=UPI0012F6C73A ---RVDRDVAEILADAGCSGWVHATTIGSPQIEhSFDADAPVVLASVYKLAVLISLCRSAD -RGDIDLASSITVDPTLWAQGPTGLAAFGDPVLSRRDLAISMMTVSDNVAADVLLDEL-GL -DRVRADLVSLGAERTRIVGGVAELHEAYDAAYSSSSTPRDCTALLSAVWTDRAASPEMCA -FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTAR -SEQSLPQVDRAIGEAARTVVT-- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium isatidis TaxID=182773 RepID=A0A343JAG2_9CLOT ------KEIKKYLESRIGTYGFFFEDLRSGFVY-GYNENVKMVAAGCIKLPIAVSLIKAVE -DKKVDFLDKIKIERKDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDII-GM -DEINKNIKEMGMENTVLKRKTGDINNE-DDASENITSALDLAILWRHLYKKTYLSKENSQ -MLIDILNRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTELVTLSKGT-FSFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9ZG23_9BACT ------------------------------------------------------------- -------------------------------RVTNRDLATMMVAVSDNSATNVLIDRV-GM -ENVNAMMSGLGLTHTRLRRKMMDVRAA-SEGRENISSPREMMTLLEQIYRGKVLTKDLTQ -DFFRMLSTHKE--SFIPRDLPDGQRIANKPGELE-GVRNDSGIVFAQNR-PYVICVMTTY -LSR-ERSGEEAISKISAAAYAMf ->[subseq from] serine hydrolase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=UPI0009EA2548 ----VERRIAEIFAEAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA -EAIDRVISELALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR -QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLS-DRQPLVDASIGRAAF--- ->[subseq from] serine hydrolase n=1 Tax=Pedobacter sp. HMF7647 TaxID=2695275 RepID=UPI00136D673B --kKLQGKLVELTKGINGVAGIYVKNLNTGKIA-VFNADSIFPTASMIKVPIMAGLFEKLD -RGDLNYSDIWQYRDSLSYDKGDVVGSLADSAINLSKVQMLSITTSDNTASLWIQKIV-GG -ENINNWLDKNGFKDTRVNSRTPGRQANQKLYGWGQTTPREMATLVEMIRNGKAVSEAASE -RMYRNMSHIYW-DDKALSQIPPTVQTASKQGAVD-ASRSEVVLVNAPHGD-YVFCIITKN -LATPSNEGWQLIVKTSDLLWHYf ->[subseq from] Serine hydrolase n=1 Tax=Dyadobacter sp. AR-3-8 TaxID=2576211 RepID=A0A4U6D344_9BACT --kKLTGKLEKALAGFKGNAGIYVRNLKSDKFA-SINADTIFPTASMVKIPIMIGVFDKIN -KGQIQFDQLLTYRDS-LKYDDGITGSLRDSTIPLPKVIHLMISLSDNTGSLWLQALAGGG -STINQWLEINGFINTRVNSRTPGRKQNQAMYGWGQTSPREMAELMAMLRLGKVISPDASE -RMYRYLGMQFW-DGEALSQIPPFIKTGAKSGAVNQ-AKSEVVMVHAPHGD-YVFCITTKN -QQQRDNEGYKLIRTVSEIIWNHf ->[subseq from] Serine hydrolase n=1 Tax=Bacillus kyonggiensis TaxID=1037680 RepID=A0A4U1D7B9_9BACI ----LVERIDELIRLCPGRISLQGEI--GDWSY-EHDSERMYSSASLIKVPILIEAFRQYE -NGVFSLGDFVEIRKDLRVGGSGVIQALEQSSWMIKDLKTLMITVSDNTATNMLIELL-GI -DSVNDSIELLGLKKTKLQRKMMDFSA-VQEGKDNYTCAADMIRCLKVIDESGFLKEESCR -EAKLILRHQQF--HKILGLLQEQGYMGSKSGSLP-GVEHDCAIIGVQGKT-AYVAILIDQ -IPE-GKSGTLTMQEIGRAVYDA- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium sp. Ag1 TaxID=1643443 RepID=A0A0M3D2Y2_9MICO ----VERRIAEIFADAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA -EAIDRVISELALRQTQLAGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR -QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLS-DRQPLVDASIGRAAF--- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetes bacterium Spa11 TaxID=2528022 RepID=A0A518K6V3_9BACT --------ILDLAQSTPARVGLAVESLDGAWSY-SVLPDEVFAQASAIKVPILWELHRAAA -AGELSLDERLTVDPANGAGGCGMLQNFLPGAMALGDLGVAMIVLSDNVATNLLIDRL-GF -DAVNALLVSQGANQTRLRRKMIDPEA-RKAGRENTSTPSEAVRLMRRLHDAEGAGDPVAA -AVLKVLRLRKE--SPVTTVLPSDTRLATKPGMLD-GLRTEWSIVEREGV-NYAMALMVDG -GDE--ILIDALVREIAV------ ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. TMED20 TaxID=1986597 RepID=A0A424HLP6_9SYNE ------------AQQKDLKTSAFMLILDDGRFA-QLEAERPMPAASSIKTPILLASLEXXD -NGDLHWNEPLILTKELIGGGAGWMAKPVGSRFPTYEVATEMIRVSDNSATNLLIERVGGQ -XAXNARFQALGLXATEVNNWLPDLDGT------NTTSARDLSRSIALVDSGETLSPXSRD -LFREVMSTSVT-DTLLPTGLLQGYRVYNKTGDIGI-AYADAGLIELPDGRRAVAGFLVQG -PFN-DPRSTDMIRALAKAMA--- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6GUH8_9BACT --kKLETRVEEIAARLDGVMGVAILDLSDGRVL-LRNADRVFPAASSIKLAILLELYRQDQ -QGKAKLDDIYAFDPKDLVEDSQIMAGLTPGVVTNRDLAQFMVAVSDNAAANILYDRV-GR -DNVNALLRGLGLSKTTLRRKMMDIAAARRG-DENVATPQEMIRLLEAIYKEKALNKQSTA -EFIKQ------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardia bhagyanarayanae TaxID=1215925 RepID=A0A543EY66_9NOCA -----EERIREIFAELPVRGRFHAVDLADGREI-GVDADDQVVIASIFKILLILEFSRQVD -AGQLDPTERVLVRAADRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP -DTPALLAAELGLAATRVIGGPRQLLEVFRPEHTTSSTAREITRLLGMIWGDEAGSPAACA -ATRDLLRRQIS-WTRLAAAFPDEVLVASKTGTLP-GLHMEAGVLEYPDGGRYAVAVFARS -DETRRIDVDLAMARSARLAV--- ->[subseq from] Beta-lactamase class A n=2 Tax=Peptococcaceae TaxID=186807 RepID=A0A1M4YVG1_9FIRM --qPLQKQLKEYLARQPGVYGIYFKDLHSGVSF-DINGDEPVTAASTVKVPVVLYLNHLVA -QGKLDWDDRVVYDSKDYQGGAGILQFAARDGYSLRVLANLSITISDNIAYRMLVRHL-GK -DNVAQFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSREHPALGE -RLLDDMAHPIY-HVGLPGKLPPKVRVAHKEGDVW-GVANDVGIVFAE--HPYILVVLSRG -ET-DVDKGFARIAEISRMVYDY- ->[subseq from] Uncharacterized protein n=1 Tax=Megasphaera sp. ASD88 TaxID=2027407 RepID=A0A2A2IL95_9FIRM --------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDAAYSVYG--NVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAINEEIRRQGMENTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDQ -TMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093BAFDD ----IRVRIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV -AGRLDETECTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ -ETICRVVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACQ -RVRAIMAQQIW-PHRLSAGFPSDVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA -HSDRLPEVDASIGAAARLALDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Lentzea violacea TaxID=128104 RepID=A0A1G8QKQ5_9PSEU ---------------AGVEGFVHAREIGDGPEA-GHGADEQVVLASVFKIPVAVAYAAEVA -AGRLDEMARTRVTPRYRIGGIGTAGCRDDVEMSWRDLALFMMTMSDNAATDVVFHRV-GQ -AAVDAVVA--GLPRTRILGCCEDLFAIVDPERTTSSTPREITTLLDAIWTDRAAAPEACE -RVRAIMAQQIW-PHRLSSGFPADVLVAAKTGTLP-GVRNEAGVVTYPDGRGYAVAVFTRS -QSLDNPAADAVIGRAGRLAVDQ- ->[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium ADurb.Bin467 TaxID=1852894 RepID=A0A1V5KEN4_9FIRM ------------------------------DPV-AINADMPLIAASVIKIPVMIEAFRQFE -AGLLSPDMAVTVRPEHRMPCGALAYMHDNLTVTAMDCVTLMIILSDNTATNLMIDML-GI -ENINSTLAALGCVQTRIARKLFDREG-MKRGLKNFITAREIGMLLEKIYRGEAVSPAASE -TMLEILKNQRL-NGKIPFFLHLGVKIAHKTGEED-GISHDAAIVFAD--RPFSMVALSNN -VDV--PMYERLIQDAALALYR-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00084FA5EF -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGIGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Amycolatopsis TaxID=2618356 RepID=UPI00106E207D ----ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA -EGTLDLGAPVTVEPGHPTPPYGLATFRHEVRMSWHDLAILMIGISDNVATDLILAEV-GK -DAVNSTLRRLGFTQTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA -DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -EDSRVPERDAFIGFAAATAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardia brasiliensis ATCC 700358 TaxID=1133849 RepID=K0F6C5_9NOCA -----------IFRNAGAQGWVHARCFGCAGAN-GLDADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRARAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL -DNVRSLVRELGLTETRIAGAPRDIVQALDPRRTTASTPREMTRLLTLIGQDLAGPAQACQ -WVRDVMREQVN-WHRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPDGSRYAVAVFTRT -ESQRLPEVDRAIGAAAVAAID-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces viridosporus T7A TaxID=665577 RepID=A0A5J6FZ61_STRVD ------------------------------REV-AVGADDPVVIASIFKVLLVLEFARQVV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GP -DTVRLLARELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWSDAAGPPEACA -FVRDLMIRQVF-RHRLASGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -RDVSRATVDAAIGRAAGI----- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces gardneri TaxID=66892 RepID=UPI00142F0073 -haAARRRITAAFADAGVTGLLHAVDIDTGTAL-GIGSDTLVPTASVHKLCLVATLYRQSS -LGLIDPTRPVEIPAEDRAPGATGLSVMRDAALSLRDLASLAVAVSDNTAADLLWDAL-GL -DTVNATMTGLGLTRTHAVQTMRELFAALDPTRTNRSTPREITALLAAVWRDEVCAGEYGE -ELRALLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASTDLPAADAVIGGAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013BDA7B0 -----VAQLDAAFSGAGVSGYLHAAEIDGAADV-GYAADELVVTASVFKIYVLLELCCQAA -EGRRSLTDRVRFAPEARTPPTGLSVMYDEIDMSVRDAAYLMMSVSDNHATDVLMGLA-GV -DDIHRRLRALGLPRTAAPHTCAELFRALTPAMTNRTTARETTSLLGMIWRDENLPAGACA -ETRRIMGLQVW-PHRLTSGFPHGIRVSGKTGTLSH-VRNEVGVVEYPDGGRYAVAVYLRV -SDRANPAADAVIGQAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Megasphaera sp. SW808 TaxID=2530045 RepID=UPI00143A252A --------------QDKAAVSVYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDTTYPVYG--GVEGGSFYGLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAINEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE -AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Jiangella alba TaxID=561176 RepID=A0A1H5MIJ7_9ACTN ------DDIAAALRRAGTDAALHVRPVDGPGEV-ALNPDAVSVAASTYKIAVLLELACQAA -EGTLSLTARQRVPAGRRSLPTGISAMLDDVDLSLRDLALLMMQVSDNTATDVVQEVV-GT -DRITARLKGLGLANTSFPHDCAKLVGSIAGTVGNTTTPRDMTTLVSAIWRDEAGPAEACE -EVRRIMAQQYA-PHRLSTAYRDGPAIAGKTGTFHGGIRNEVGVVDFGGGDRYAVAVYLRQ -HEYDDGAADAVIGEVARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus sp. S14-83 TaxID=2489213 RepID=A0A3G8YRV9_9DEIO ------------AQSYGGEVGLAISTLEGEVLV-CLNAERAFLSASTIKVPLLLLALERVQ -TGQLRLNERHTLKPADRVGGAGILHELGAGLLSLEDLLTLMIIVSDNTATNMVIDLL-GV -DAVNAWLFERGCRQTRLVGKLEQQNAAQLLGERNRTSAAEQAELLLGLWQGQRLEPPVRQ -LALSILGRQHYRDILGRSLLRSRYQTYTKSGELL-GVHHDVGLLLLP--RPLCVALLSEG -GSDR------------------- ->[subseq from] serine hydrolase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=UPI00037A21DE ------KTIRDIFDAAEVDGYLHVRDLDGDDEV-DYRADAPVVLASVFKIPIALEYARQAA -AGRLDRAGRHVVTDADKEGGIGTDGCMHDVEMSARDLAYMMMTMSDNAATDMVLGLV-GR -ENVRATLDELGCHDTSVTGCKELFASVRDPEHTASTTPREITKLLAAIWRDEAGPAEACA -EVREIMGRQIW-PHRLSSTFGDEIRVSGKTGTLW-GVRNEAGVVEYPDGKRYAVGVFLRS -ESFRLPRADAAIGLAARAAIDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2570 TaxID=2512221 RepID=A0A4R7ZM59_9ACTN -----NARIRAVFDDAGVRGWLHAVALDEPESTvEVDADGIVPLASVYKLPLLAGFCRLVD -LGEVDPRERITLDPSAKTEGPTGLSMFADPVVSLRDLALSMMTVSDNASADALLDIV-GL -RRLAGMLESFGLHRTWVRRGTAGNLRVYEAANASASTARDMTLLLQRLWSGELLSPEQTD -FVKTTMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGEAFAIAVFTLA -ARNRQPRVDTAIGQAARLAVD-- ->[subseq from] D-alanyl-D-alanine carboxypeptidase n=1 Tax=Oceanobacillus oncorhynchi TaxID=545501 RepID=A0A0A1M5T2_9BACI ---------------------------SGENEI-AFNENKPLRSASIIKLFILAAAYYEEE -KENIDLSKQVHLSPSDMVGGAGVIPYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL -DTIHAFIQQIGGKHTKLERKLMD-EEAIKLGLENRTSCYDVMLLLDLLTENNILPKHRQE -QMLTILENQQF-NSKLTAAYDSSIKTFHKTGELT-GAEHDAAIFQTADKQ--LKAVMLTE -GWTNNGEGQQFHQRAGAHIYHY- ->[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus marinus TaxID=1219 RepID=A0A163PE06_PROMR ---KLSNRWRELAKQQDLQASAFLLVLDDGRYA-ELSAETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DILNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSVS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-SRSTELIRNMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces exfoliatus TaxID=1905 RepID=UPI0010FB6E26 ---AVRTRITAAFTDAGVTGQLHATDIDTDAAI-GVGSDVTVPTASVHKLCLIATLYREAS -LGRLDLRRPVDIPAEGRSPGATGLAMRDAARLSLRDLATLTVAVSDNTAADLLWDAV-GL -DTVNRCMTDLGLTRTVAVQTMRELYAALDPALTNRSTPRETARLLAAIWRDEVCAGERAA -QLREVLGLQAW-SHRLAAGFPDDVRVSGKTGSLPT-LRHEAGVVEYPDGGRYAVAVFTRA -AAVTLPAADAVIGRAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=UPI001414F4FF ----------------GARGFLHAKEIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVGKRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ -AAVDRVLADLGLGRTRLIGCCEDLFAVLDPERTTSSTPREITTLLDAIWTDRAGEPAACE -RVRAIMARQIW-PHRISSGFGSDVAIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=A0A4D4KEK1_9ACTN -----EKRIAEVFAAADAEGRLHAVDIDPGRQL-GLGVDDQVVIASVFKILLVLEFARQAG -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDARHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RRRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces paucisporeus TaxID=310782 RepID=A0A1M7H351_9ACTN ----ARGRIQAAFADAAVTGWLHARDIDSGAQV-DAGGDQEVCTGSVHKLCLLVALHHAAA -EGRLDLAEQTECPPAGRTPGPTGLAAMLDPVMSLRDMAYLMAAVSDNAAADALLERV-GL -DAVNHATARLGLTRTRAVHTFGEILTALDPAGTNRSTPREMTGLLGAVWRDEACTPEHGA -AIRRLLALQVW-PHRLASGFPDDVRVAGKTGTLPT-LRNEVGVVEYPDGGRYAVAVFTRT -PNATLPAADAAVGTAARIAVD-- ->[subseq from] Secreted beta-lactamase n=4 Tax=Streptomyces TaxID=1883 RepID=D6BBB4_9ACTN -----------------------------EGEI-ALGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL -DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACS -QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS -REASRTEVDAAIGATARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5W3B5_9PSEU ----TSEDLAALFDRIGARGWVHARELDGDREI-GLDPDEPVVLASVFKLPVLVTYLRAVA -AGELDPAERVRIGPRHRIGGIGTAGCADDVEMSWRDVALFMMSMSDNAATDVLLARL-GL -DRVHEVLASLGLTRTRLIGGCEDLFAVYDPERTTSGTPREITSLLAQVWPDP-------- -ELRAVLGKQVW-PHRLSAGFPDEVAVAGKTGTIP-GLHNEVGVVTYPDGRAYAVAVFTRS -ASHRQPALDAVIGASARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Flavisolibacter sp. 17J28-1 TaxID=2502779 RepID=UPI00104A609F --kKLQQAIEQMAVGFGGQVGIYVKDLHSGKVA-AYNADTIFPTASIVKIPIAVGIMQKLE -RGELTYHQPLVYKDSLLYPGVDILGSFKNGEIDLSKVLMLMLTTSDNTASLWLQSLAGGG -TTINVLMDTLGFPQLGVNSRTPSREADREVYGWGQMTPRAIAGLMEEIYRRRVISPAASD -RMLRLLNRNYWDAEALSEIAP-YAAVFSKNGAVNE-SRSEVVLVRGKKSA-YLFCIATKN -NHTPANQAWTLTRKLSAYLWQHf ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6NI39_9BACT --kKLEAHIDEITERFDGVMGISIVDLTDDRAI-LKNAGHVFPTASSIKIAILLELYRQEQ -QGKAKLDDIYTFEAKNLVDGSQIMTGLTPGVLTNRDLAQFMVAVSDNAAANILIDRV-GM -QNVNATLRNLGLTKTMLRRKMMDIAAARRG-DENVSTPQEMTRLLEAIYKGKALDKELSE -IFMK-------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium CG08_land_8_20_14_0_20_41_15 TaxID=1975086 RepID=A0A2H0X8V3_9BACT ----LKKAIEKEIKGANGKYGIVVKNLKTGESC-FANEHMKFEAASLYKLWVMATVFNQIQ -EGKLSKNEVLSREVEELNRDSEVAELTEGTILSVEDALAKMITISDNYAALLLAKRI-GL -SIVQTFLKDNLLEESIIG--EP-----------PITTAYDVALFFEKLYNGELANQENTK -LMLNLLKGQLL-NHKLPKYLSEEVTVAHKTGELGI-FSHDAGIVYGEKGD-YIIAVLSES -DD--RLAAEEQIAKISKSVYEYf ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535K8V7_9CHLR ---ELIQRLDGLLASFPGGAGIWVADPSVTTPLfTHDPEEQVIAASLYKLGVLAEAERRVD -AGELHYDDTITIEPEDITADGSF--EDAGTHLTLDEALEAMITISDNGSALALWHIL-GG -ANIDATLEKAGVKNFHVA---------FDDTEDNWATPHAVGTFLTLLAKRQLISPAASD -RMLARLERQQI-NDRLPAQLPPDVVIAHKTGNLS-GVLHDAGIIYTKTGPR-VVVAMTWD -AP--EEEAANFISSIGSLVYS-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus megaterium TaxID=1404 RepID=UPI00041DB577 -----------------DHFSVYIET--DEGTI-SINPAQLRCAASLAKLPILIAGFRQLD -KNPHLQDKLVYIKRKNMVGGAGVINYLSHSHYSYRNLLELMIIVSDNTAANVLLDIL-GV -ETINQLTKDADCQQSIIQRKFMDLQAK-ENGLDNYTSAYDIAKLLHLISENKFLTKESQK -MILTILANQQF-TNKLPSYLQDEIQFYHKTGELQ-GVTHDAGIMKYQDKT-IHVVLLSEG -IS-LNAESERIIADIGHLLIR-- ->[subseq from] UPI00143EC2E6 UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI00143EC2E6 --qSLKSNLESIIKDKNATIGVSVWNLEKGEKT-SVNGDSNLPMMSVFKLHIAMTILDLVD -GGTLKLDQKIKFSKSELMQWSPMRDKYPNGGIPLSEMIKYVVAQSDNNTCDILLNKIGGL -KTVENYIHKIGVTDFWAVANEKMMHKVDGAIYKNLTTANASNLLLTKLYT---------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium RBG_16_64_32 TaxID=1797658 RepID=A0A1F8RIZ5_9CHLR ---ALAALIRTTLSGYAGTYSVVVRNLDDGRSA-SWNAEEVYTAASLFKLALLLEAYRQRD -SGEIDFSEVLTLDEEYVEYNFGTLEAEEGDQLTLADALKAMIIVSDTPTAVMVQDVV-NP -VRVDQTLRSLGINDMSVLTEE--LP----------TTARDMALLMEAVAAGQGVTDESRR -QMLGLLLQESI-RGGIPSGVPPNSAVAHKTGNLDN-LTHDVALVWGPGG-PYVIAVLSDR -SWES-----EPLATVSRAVWDYf ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A6A1YS71_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDIKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] serine hydrolase n=1 Tax=Sporosarcina sp. ZBG7A TaxID=1582223 RepID=UPI0009DFE7B0 ---QLKEELDRIANNAVGDVSIYATT--PEGVI-AIREDEVKRSASILKVPVAMACLAAAD -RGEIDLDTLLKIEE--PVGGSGVLAYMSGMEITLRNALTLSIIVSDNTAANLVIEHV-GI -ERIQKFFKHVGATHSQLTRKFMDYD-ALARGLENVATAKDMVRFLMCLDPSENLSLTSKQ -QLKTIMRDQQL-IDKLPAFQPETLIIGNKTGTLP-GVEHDIAYFENGER-CVNIAVLTTD -WEYN-HDGQQTLAQIGKSIIKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chersina TaxID=47854 RepID=A0A1C6V032_9ACTN ------ERIGEIFQRAGISGCLHVVDVDPGREV-ALRADEQMVIASVFKILLVLEFARQAV -AGQLDPAERVVVDAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPDHTTSSTAREITRLLGLIWRDEAGPPAACA -LVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART -ERLSTRDVDLAMGDAARAAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. OK283 TaxID=1881049 RepID=A0A1H8RJG6_9SPHI --kKLTAQLQDAVKGFHGQAGIYVQNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE -KGELHYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -NYINNWLQQNGFKAMRVNSRVAGREAIRKIYGWGVSTPYEMCRMFTMIRKGEAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NTGTSNEAGLLIKKISALLWHYy ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A3Q9J5F1_9MICO ----VERRIAEIFADAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA -EAIDRVISELALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR -QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLS-DRQPLVDASIGRAAF--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces viridifaciens TaxID=48665 RepID=A0A1L9DWF6_STRVF --------------------LLHARDLDTGAEL-ALGADTPVSTASVHKLCLLVTLYREAA -AGRIDLTRPVDLPATGRTPGRTGLSAMLDAALSLRDLAYLALAVSDNAAADVLWDEI-GL -DTVNRTMAELGLTRTIAVHTVRELFAVLDPAFTNRSTAREMTALLAALWHGDACPGEPGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATSLPTADAAIGTAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Plantibacter sp. PA-3-X8 TaxID=2480625 RepID=A0A3G8VM47_9MICO ----IAARIESVLEPLGVRGYVHAVDIDSGVEV-GLDADTDVVTASVFKLPVLVELARQYE -AGALDPRRRIRVGADERRTDGPTLSILLDDVLSLRDLSVLMMSVSDNRATDLITDLV-GL -DSVNATMRSFGLERTVVPVDCDALFRVSNPESNDRTTPREITTLLAAVWRDEVIGAAAAA -EVRRVLGLQAW-SHRLVAGFPSRVKVSGKTGTLFF-IRNEAGVVEYPDGGRYAVGVFLRE -SSLRHPDADRAIGTVARVAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536DJM1_9CHLR ---ELDRRIATLQRGFQGQLGLAATNLATGEQV-LVNADQLFPTASVIKVSVLAELFAQAE -EGRLMLDERLQMQASHIVGGSGVLRELLPGLPTLTDLAMLMVVLSDNTATNMLIDRLGGC -DVINRRVQGYGFASVALHNRVDFEKIGSDVRRFAEATPADLARFMERLAREELVSASASR -KMLRIMSRQQYLD----------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Sulfobacillus thermosulfidooxidans TaxID=28034 RepID=UPI00040FBEFC ---------------------------QTHETL-TREPDRVMETASVIKLPIMAATFQYLA -DEHKTLSEPLTLQVEDMVDGSGILQHLSPGLLSIKDVMTLMIIVSDNTATNMILRQV-GI -PRVNRFIQSLGLSQTRLLKRIDF---TIPG-PIGLATSRELGMILTQLYHRTLVNKDASD -IMWDILCRQQY-NTIMTRHLPPKVQIGSKSGSLE-GIRNDVGIITTPWGD-YVLAILSEH -SRHIDNEALVILPQLSRIIFDYf ->[subseq from] hypothetical protein n=1 Tax=Heliobacillus mobilis TaxID=28064 RepID=UPI0012D77217 --qVLKQRVQGYLDERPGQVSVYVQDLTTGASF-DIGGDQIYMTASTHKLPTVLYLYTLAA -QGKVDLNSTLTYTSDYYRQGTGIMQGEPGKEYKLRELARLAIVYSDNAAWAMLLDYL-GD -DNLGQFEQSIGGTVTYYDDNSNPL-----------TTPRDMGKYLAYLSVFRDNQPALGN -EIFNALENTVY-NDRIPSELPAGTVVAHKIGSLND-KFHDVGIVFAPNR-PYIISIYSKD -GW--EAASVQTLADLSRIVYDY- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2N5K906_9CHLR -------ALTTLLDQAPGRYSVCVG-TATGVPIyDYAGKVVRSAASLIKVPLALAIYDTLP ----HRLDEPVTLREGDRVAGEGSFDGAPPGTRTVRELIGHALRESDNTAANLLIERI-GF -EAVNHWLVARRL-QTRLQRKFMDFDA-LHAGRDNLTTAADMCVLLLALL-----QPRYAD -LL--AMLRQAVGTGKLEAGLPPGTFIAHKVGDLP-GVEHDAGIIFAANG-PYLVAVLAVE -LQ-DAAAGRHTIAEVSRLVWE-- ->[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus sp. MIT 1303 TaxID=1723647 RepID=A0A163E7C0_9PROC ---TLSNRWKDLAKQQDLQASAFLLVLDDGRYA-ELSPETALPAASSIKTAILLVALELID -SGQLSWNEPLKLTKEIIGGGAGWMAKPLGSQFPAHEVATEMIRVSDNTATNLLIQRIGGK -DVLNARFNALGLSSTVVNNWLPDLQGT------NTTSSHDLARAIALVDTGKALSPRTRD -LFREAMSTSIS-NRLLPGGFLKGYRIYNKTGDIGI-AYADAGLIELPDGSRAVAGFMVKG -PFND-PRSTELIRDMAAAM---- ->[subseq from] serine hydrolase n=1 Tax=Clostridium tarantellae TaxID=39493 RepID=UPI00128C74EB -------EIKKYLESRVGIYSFFFEDLASGYTY-GYNENVKMISAGCMKLPIAVALIKEVE -EKKLDFLDKVKIESKDKVFGTGIIHEFGEREYTVFELLVAMLIQSDNTAANKIIDMV-SM -EKINIIIKELGLKNTELNRKTAD-ERNYHDKLENYTSSYDLCLIWKNLYNGSFLNKENSQ -MLIDILERQQI-KNKLALYIPDNYDISSKTGDKQ-GVENDTALIHTSKGN-FICTVMSSK -IPNS-VYGTITLAKSGKMMWD-- ->[subseq from] hypothetical protein n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI00062A12FE -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRNVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A483DRY9_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRNVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Geodermatophilus pulveris TaxID=1564159 RepID=A0A239BT43_9ACTN ---DVAARIADLATDFTGQLAVSAVDLTTGERV-EWQPDLLLPTASVIKESILIALLRAAE -AGTVDLADRVTLEASERVGGSGVLKLFEGGLPTVRDVATLMIAVSDNTATNMVLDLIGGP -EPVNRAMAELGLDSIRLHNAVDELIG-NDVRRLGEATVRDLCELGRLIATRKAFGEMVSA -TAEEVLATQQYLDQAMRYTLAAPLSVASKTGSFT-GTRVDAGIVRFAAGGGFCYAVANHE -AS--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium CG_4_10_14_0_2_um_filter_42_7 TaxID=1975073 RepID=A0A2M7TDH8_9BACT ----LKKAIEKEIKGANGKYGIVVKNLKTGESC-FANEHMKFEAASLYKLWVMATVFNQIQ -EGKLSKNEVLSREVEELNRDSEVAELTEGTILSVEDALAKMITISDNYAALLLAKRI-GL -SIVQTFLKDNLLEESIIG--EP-----------PITTAYDVALFFEKLYNGELANQENTK -LMLNLLKGQLL-NHKLPKYLSEEVTVAHKTGELGI-FSHDAGIVYGEKGD-YIIAVLSES -DN--RLAAEEQIAKISKSVYEYf ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000486D6F9 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMHTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Achromobacter sp. TaxID=134375 RepID=A0A0M7JAD0_9BURK --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARHTDRVQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAAERAGGTGILAQLPSVTLSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SB0666_bin_14 TaxID=2604857 RepID=A0A6B0ZXJ5_9SYNE ----LEERFQALAAAQDLLVGAYVAVLGDGRHA-SLNPDRATAAASAIKTPVLLLTLLARG -QGELRWDETLQLQPHLVGGGSGWMGAEPPGRFPLYMAAREMITVSDNTATNLLIERLGGM -EAVNRRFLALRLQGTRVNNWLPDLDGT------NTTTPRDLALTLAMAESDALLSQRDRD -RFRAIHGSSRP-NSLLPLGFLQGVRILNKTGDIGT-AYADAGMIELPDGRRAVAAFLVEG -TEYNSPRMRRLIQNMAAAT---- ->[subseq from] VEB family beta-lactamase (Fragment) n=1 Tax=Pseudomonas aeruginosa TaxID=287 RepID=A0A3G6V737_PSEAI ------------------------------------------------------------- ------FEQKIEITPQDLLPWSPIKEEFPNGTLTIEQILNYTVSESDNIGCDILLKLIGGT -DSVQKFLNANHFSDISIKANEEQMHKDWNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGPAATNDVGV----------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110F7833 ------ERIREVFAGAEGVLHAVAIDTEPGTQEvAVGADGPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL -DTVRLLAGELGLPGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA -HVRELMARQVF-RHRLVSGFPDEVIVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART -RGASRPAVDAAIGATARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Gordonia sp. 135 TaxID=2676309 RepID=UPI0012BB2A94 ---RIDRNVAEILADAGCSGWLHATTIGSPQISySYDADAPVVLASVYKLAVLISLCRSAD -RGEIDLTSPVTVDPTRWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVLLDEI-GL -DRVREDLIGLGATSTRIVGGVAELHEAYDAAYTSSSTPRDCSTVLTAVWTDRAASAEMCA -FIRNTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTRS -ARPALPQVDRAIGELARTVVT-- ->[subseq from] serine hydrolase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=UPI0014285341 ----------EIFEQAGVQGWLHARCLDCGAEI-GDGADEPVVLSSVVKVLLVLELGRQIA -AGQVDPTDRLRATAAYRLGGPGTSGCRDDVEYSLRDAAYLALSLSDNTAADLLFERV-GL -DNVRSLARELGLTRTRIAGALRDLLLALDPRRTTASTPREMTRLLELIARDEAGPPATCT -WLRELMSLQLN-QHRLPSAFPSNVLVWGKTGTLP-GLRNEIGVVEFPNGARYAVAVFTKA -RVHRLPQADRAIGAAARTAIE-- ->[subseq from] Serine hydrolase n=1 Tax=Megasphaera sp. TaxID=2023260 RepID=A0A3C1CMZ7_9FIRM -----------------TDLSIYCRPLEQGTPV--VYHERVLPSASLIKLPIMSTLFRKEK -EGTVSFSEKLRITSP--VE-GGSYYKRGGTLATISELIFHMIVESDNTCTNVLIDRL-GM -DAVNEEIRRLGMTHTILQRKMMDFIAS-RDGRENMTTVSDMGRFFSLLSRGHAVDAARDQ -RMLDILSHQED-NCILPAQLPHTVRVDHKTGELD-GIYHDCGLIYAPSG-PFILCLMADG -VS--------------------- ->[subseq from] Uncharacterized protein n=2 Tax=Gordonia TaxID=2053 RepID=L7KUA8_9ACTN ----VDRDVTETLADAGCSGWIHATTIGSPRIGySFDADAPVVLASVYKLALLISLCRSAD -RGDIDLTSSVTVDPTQWAQPTGLAALRDPITLSRRDLATSMMTVSDNVAADVILDEI-GL -DRVREDLATLGVANTRIVGGVAELHQAYDAAYSSSSTPRDCTTLLSAVWTDHAASNEMCA -FIRDTMRRQVF-TSRLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTSS -ARPALPHVDRAIGEVARTVVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_02_FULL_39_13 TaxID=1802505 RepID=A0A1F7Z314_9BACT ---KATVAFKSMTKELSGVYGLYVLRLDDGSNY-GVNENEIFQAASLIKLPVIFAMYKEAE -GGNIDLDNKYRLKRTDKVAGSGSLYQKSEGYITYREMVRLMGKQSDNTAFNILVKLL-GK -DKIESVIKELGMIQTSLDKNE--------------TTPEDVGIFFDRLYNGNLISDASTN -EILEDLTDTIY-EDWLVAGIPGVIRVAHKYGRELH-IVNDAGIILSD--KPFVLVIMSKG -IV--EKEADEIFPVITRAVYE-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium tunisiense TaxID=219748 RepID=UPI0003178386 ------KEIKRYLESREGNYSFYFEDLKSGFIY-GFNENVKMPAAGCIKLPIAMALLKEVE -NGKVSLNDLISIGDEDKVSFFGIIHEFSEKQYTLKELLVAMLIQSDNTAACKIINIL-GM -DKVNSLINDMGLKSTKVNKYPSEVKL--SDNEENITTSYDLSQCFKLLHNNTALSKEHSR -LIIETLKRHQL-NTRIPFYFQREANTANKIGTLET-VENDTALLNFSKGD-FVYTVMSNN -LP-TNVYGITTIARSGKMMFD-- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium varium TaxID=856 RepID=A0A3S4V8G7_FUSVA ----------NIKKYDNKKYGIIIKSLESEFFL-KVGNMEAYPAASLIKLPILYELFNNSK ----YNLDEKIEITLKDKVGGFGIIQYHNNVKLSLRDLAILMIILSDNTATNILIDIC-GM -DNINFTLKKLGLKDTKLRRKMMDLKSK-NMGLDNYTSPYDMIKLLEVLNK--------NE -EIISIMKKQLC-NNKISHFIEKKIDFAHKTGDLPQ-IEHDVGIFDIEDKK-IIVVVMTKN -FENR--DEIELNNKVGEFI---- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Melainabacteria bacterium HGW-Melainabacteria-1 TaxID=2013813 RepID=A0A2N1UQR4_9BACT ----LASRFRTHLNRLSAEAGWAACNLRSGRSL--VFNDRRFLAASTIKLPLLLIYAQHRH ---QAIFKEPYIYDPQVYCEDSPCFDAVVPGTVSWDDIATWMMTLSDNTATNLLLDYF-GL -DAIQNWIQHQGFETMALNRRMMDLDAR-SRGIDNWTTPGEMMQLMARLANGSLMPAEASN -WSLEILHRCED-REKIPYFFQTPIRVANKPGELP-GIRCDVGYVHDEQHE-IVMAYS--- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. H6 TaxID=421122 RepID=A0A366CQH9_9MICO ----VERRIAEIFAEAGATGFLHAREIGGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA -EAIDRVISDLALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR -QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLN-DRQPLVDASIGRAAF--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sparsogenes DSM 40356 TaxID=1331668 RepID=A0A1R1S9E3_9ACTN ---SIEEKVAGVFEGAGARGWLHAIPVGGGREV-GVGADEPVVIASLFKILLVLEFARQSA -AGQLDPRERVLLTAADRLGGWGTAGCADDVEMSLRDLAFFALSVSDNTAADVLMRRV-GL -DTVRLLAAELGLDRTVVVGGPRELLEVLDPRRTTRSTARDVTRLLALIWRDEAGPPRACA -LVRELMARQVF-RHRLASGFPGDVGVAAKTGTLP-GLHIEAGVVHRPDGGCYAVAVFAET -RDTANPAVDAAIGRAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces albidochromogenes TaxID=329524 RepID=UPI00110F7266 -----EERIREVFAGAGAEGSLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAGELGLAGTRIVGGPRDVLDVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA -WVRDLMARQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART -RDASRPVVDAAIGATARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis niigatensis TaxID=369932 RepID=A0A2N3WK24_9PSEU -----REQIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVAARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLCHRL-GQ -ETIDRVLADLGLARTRLIGCCEDLFAVRDPARTTSSTPREITALLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVRVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -HSDRLPAVDASIGAAARLAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis rifamycinica TaxID=287986 RepID=A0A066U0S4_9PSEU --------------AVGVRGFLHARRLGSPAAV-GVDADAPVVLASVVKVPLAYEFARQVA -AGLLDPADRVRVTAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTTVIGAPRDVLRALDPQRTSATTPREMTTLLSAIWADDVGAP---- --VREWMSAQVS-WHRLAAGFPPEVAVVGKTGTMP-GIRNEIGVATYPDGAAYAVAVFTAG -GAETRPDIDRAIGDAARAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B8D930 ---TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGIASYADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DALARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Beta-lactamase n=1 Tax=Spirosoma radiotolerans TaxID=1379870 RepID=A0A0E3ZW44_9BACT ---TLERQLRAALTGFRGEAGIYVHNLRTGKTV-AINADTLFPTASTIKIPIQCGLFDKIH -KGELKYGNPIVYKDSLHYDDGIVGSLKDGAKIPLNEVVMLMETVSDNTGSLWCQALAGGG -STINAWLDANGFHQTRVNSRTPGREAHRTRYGWGQTTPREMADLMTYIRQGRAVSPDASE -EMYRNLGRQFW-DNDGLSQIPPEIKTACKNGAVNQ-SRSEVVFVHAPHGE-YVYCIMTKN -QKDETNEGFVLLRTVSAILWHHf ->[subseq from] Beta-lactamase n=2 Tax=Clostridium TaxID=1485 RepID=A0A174HJD8_9CLOT ------KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVPMIAAGCMKLPIAVSLIKAVE -DKKVDFMDKVKIQSGDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIV-GM -EQINEDIIAMGLKNTRLNRKTNDERTA-ITDVENITTAYDLSRIWKHLANGTFLSKDNGQ -MLIDILRRQQI-KNKLALYIPDDIEISSKTGDKK-GVENDTAYLELPKGK-FTFTVLSQD -IPNS-VYGTVSLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. S4605 TaxID=1420897 RepID=A0A317K8C5_9ACTN ---------------------------DGGREV-AVRADEQVVIASIFKILLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELGLSRTRIVGGPRQLAEVFDPERTTSSTAREITLLLGLIWRDEAGPAEACA -MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM -ADTRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Deinococcus irradiatisoli TaxID=2202254 RepID=A0A2Z3JBH5_9DEIO ---------------HPGEVGLYVCALDGTVLT-TLNAEQVFPAASTIKVPLLLLALERAQ -AGTLDLAERLTVHSGDRVGGAGVLHELGAGLPSLQDLLTLMIIVSDNTATNMVIERL-GV -EAVNAWLAAGGYEHTHLVGKLEQHNAAQRRGERNRTTAGEQVRLLLDLWRGAALDETHRA -LALSILGRQQY-RDILARRWPLDYAAHTKSGELV-GVHHDVGLLMLP--RPLCVALLSRG -GTDR------------------- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CFH S0261 TaxID=1644109 RepID=UPI00106FEAD1 ----ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA -EGTLDLGAPVTVEPGHPTPPYGLATFRHEVRMSWHDLAILMIGISDNVATDLILAEV-GK -DAVNSTLRRLGFTRTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA -DVRRWMELQVW-PHRLRSGFPDGIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -EDSRVPERDAFIGFAAATAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Megasphaera hexanoica TaxID=1675036 RepID=A0A344MHM6_9FIRM -----------------TDLSIYCRPLEQGTPV--VYHERVLPSASLIKLPIMSTLFRKDK -EGTVSFSEKLRITSP--VE-GGSYYKRGGTLATISELIFHMIVESDNTCTNVLIDRL-GM -DAVNEEIRRLGMTHTILQRKMMDFIAS-RDGRENMTTVSDMGRFFSLLSRGHAVDAARDQ -RMLDILSHQED-NCILPAQLPHTVRVDHKTGELD-GIYHDCGLIYAPSG-PFILCLMADG -VS--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A349BXR0_9FIRM ------------------------------------------------------------- ---------------------------------TCADSLRYMITESDNSATNRIIDYV-GM -DNINRFIEKYGFTETKLQRHMLESSSR-----DNFSSARDAGICLAMIYDGTYVSEEASG -TMRNLLLQQER-RGKIPAGLPSGTKCGNKTGELNY-AENDAAIIWGPSCD-YVLVVFAGN -ISAP-GTAQSQIRHLSALVYE-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora eburnea TaxID=227316 RepID=UPI000B811F23 -------QVREVLERPGVSGCVHVVDVDDGREV-AVRADEQVVIASVFKILLVLEFARQVA -AGQLDPTERVLVRARDRLGGWGIAGCADDVEVSLRDLAYFAMSVSDNTAADLLLHRV-GP -DVLPMLAAELGLPRTRIVGGPRELVEVFDPRHTTSSTAREITRLLGLIWRDEAGPPVACA -AVRELMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVYART -ERLSTRDVDLAMGAAART----- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora eburnea TaxID=227316 RepID=A0A1C6TVI6_9ACTN -------QVREVLERPGVSGCVHVVDVDDGREV-AVRADEQVVIASVFKILLVLEFARQVA -AGQLDPTERVLVRARDRLGGWGIAGCADDVEVSLRDLAYFAMSVSDNTAADLLLHRV-GP -DVLPMLAAELGLPRTRIVGGPRELVEVFDPRHTTSSTAREITRLLGLIWRDEAGPPVACA -AVRELMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVYART -ERLSTRDVDLAMGAAART----- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0013634D67 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLYRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_68_4 TaxID=1805077 RepID=A0A1Q7HXW0_9CHLR --------------SFPGGAAIVVQDGATGKILyQRDPDEEVITASLYKLGVLLEAERRVD -AGTLRYSDSITIEPEDVTEDGS--YESAGTTLTLDDALEQMITLSDNGAALALQRIF-GA -HEINATLAALKIEPFTLAEDPSE---------DNAASPRAIATFFTQLAQHTLVSKAASD -RMLQRLERQKI-NDRLPAQLPPGTIVAHKTGNLGF-VTHDAGIIYGKAGEPMVVVAMTWN -SSED--EAIDLIQSIGSLVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535RPC6_9CHLR ---------DSRISSFSGGAGIVVQDGVTGKILyQHDPDEEVITASLYKLGVLLEAERRVD -AATLRYTDSITIEPEDVTEDGS--YESAGTTLTLDDALEQMITVSDNGAALALQRIL-GA -HEINTTLAALKIQPFTLAEDP---N------DDNVASPRAIATFFTLLAQRTLVSRAASD -RMLQRLERQEI-NDRLPAQLPPGTVVAHKTGNLGF-ATHDAGVIYGKAGDPVVVVAMTWD -SPED--EAIDLIQSIGSLVYA-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. SB0676_bin_10 TaxID=2604869 RepID=A0A6B1F5K6_9SYNE ----LEARFQELAASQDLLAGAYVAVLEDGRHA-GLNPDRPMAAASAIKTPILLLTLLARS -QGDLRWDETLQLQPHLVGGGSGWMGFEPPGSFPLYMVAREMITVSDNTATNLLIERLGGM -EAVNRRFLALRLHGTRVNNWLPDLDGT------NTTTTRDLALTLAMAENSQLLSRQDRD -RFRAIHGSSRP-NSLLPLGFLQGVRILNKTGDIGT-AYADAGMIELPDGRRAVAAFLVEG -TEYNSPRMRRLIQNMAAATAK-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium carnis TaxID=1530 RepID=A0A3P6K755_9CLOT ---SLEARIEAELISYAGKMCVYVNDF-KGNTI-EIGADEKFETASCIKSFILADLFSQVE -NGTKDLYEKLKYTKKNYINGSGVIQSLDEGVMTAINFAKLMIIVSDNVATNILIDYL-GI -DHINKTIQELGFKDTILHNKI-DFEK---YDKLGTTTPRDYGRLFELIAKKELISEEVSN -KMLDIFKMQHY-NSMIVRDFPQYIYVASKSGSMD-ACRNDGGLVFTPYG-PYVIVMFNKE -FHDSNHDATVYGGKVSRMIFDEf ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FZ84_9PSEU ---DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAKEVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ -ETICRAVADLGLSRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSDVQIAAKTGTLP-GIRNEAGVLTLPEGRRFAVAVFTRA -HSLDLPEVDASIGAVARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. 02-925g TaxID=2022503 RepID=A0A260PSQ6_9NOCA -----TEHLRAVFADAGCRGWVRAERTDGTGTFvDFEGDDPVVAASVWKIVLLVATTRAFD -DGTLIPTDTVRLVPAQCSPPTGIASYADPVTMSWRDVARSMITVSDNAAADALLGAL-GM -DTLTRVIDDLGLEHTRIVGGTKALGDGFDPAYTSCTTPRDSNAVLRAIWSGTAASPEQCE -YMKHVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEKPVAVSVYTRA -ARMDLPLVDQAIGAAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535K930_9CHLR ---DLIRQLDGLVASFPGGAGVWVSDPNVPTPLfTHDPDEQVIAASLYKLGVLAEAERRVD -AGQLHYSDEVVIQPEDITADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG -GNIDATLQKARITDFHVALDESE---------DHWATPRAVGTFFTLLAKRQLISPAASD -RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA -PD---EDADNFISSVGASVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A521X1J1_9CHLR --eDLEKQFRAIGASTTGTWTAALTDLTTGEHI-AIDERRPMPPASLAKVPVLTALYQAVD -DGAVRLGDRVRYEEGHRSLGSGVLSMMSPGVMSVRDAAVLMMTISDNSATNMCIDLV-GL -DAINAKMRALGLTETQLMLRLGDPRIEMDARNMSLSSAGDIVRLLTLIARREAVLPESCD -DMLRIMRRCT-GRAELSKLLPRENWVAEKGGAMTNGVRCGGGIFRSPRG-FFALAVFAEG -GLNHESDANVFLGRMGKAAWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium uliginosum TaxID=119641 RepID=A0A1I1KFS9_9CLOT ---------KRYLESRIGTYGFFFEDLNSGFSY-GYNENVQTVAAGCMKLPIAVSVIKAVE -KEKISFLDKVKIHQEDKVYGTGILHEFDDREYTIFELLVAMLIQSDNTAANKLIDIV-GM -DVINEDIKAQGLKNTHLNRKTSDERSA-SKGIENITSALDLSHIWKHLHEATFLSEKNST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKT-GVENDTALIQLSKGD-FVFTILSMA -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=UPI00100853CF ------QRIHNAFAQAGATGWLHAVDIDTGAEI-QAGADHPVVTASVHKLCLLLTLHQHAE -QGLLDLTEQLECPPAGRTSGPTGLAAMLDPVISLRDAAYLMTAVSDNAAAELLLGRV-GL -DAVNTTTRKLGLTRTRALHSFAQTLAALDPSRTNHSTPRDMTRLLTLIWRDESCTPEHGA -AIRRLLGLQVW-PHRMASGFPDDVHVAGKTGTLPT-LRNEVGVIEYPDGGRYAIAVFTRA -ANATLPAIDAVIGTTARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Megasphaera micronuciformis F0359 TaxID=706434 RepID=E2ZAK6_9FIRM -------------------------------------EDVLMPAASLIKIAVMIEAFRRKK -EGTLDFSECLTVN--DVVEGGSFYIKRRDDSVPIYELIFHMITESDNTCTNMLIRSL-GV -ERINETVRSFGLVKTKLRRHMMDFEAA-RRGEENTTTMRETSELLSLLAQGRCVGPTEDR -AMIEILAAQED-NCLLPAQLPHNLTVAHKTGQLE-GLFHDCGIIYGRKK-PLICAIGARN -VTAE------------------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus circulans TaxID=1397 RepID=UPI000BA53B0E --eKLSKRIDKIVQEYEGHLGIAIEW--KEQSF-LLNENDIFPSASLIKLPVLIEGFMQSS -SGILDLEDLVKVNSLQKTGGAGIVQYMSPQSLSIRDLLTLMIIVSDNMATNYLIERL-GM -DNVNRRCQQIGMSSTILQRKMMDRE-ARERKIENYTSPQDILRCLKSIYNDKN------Q -SGKTILDHQQL-LDKLPYYHRSGIRIANKTGELDK-VEHDCAIIEYEDET-IFIAVLTDQ -LTAN-QKGKEIIQLIGASIFE-- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus massiliensis TaxID=1465765 RepID=UPI00028A0C27 ---QLNSALLSMSAGMEGEVSIAIHT--DEGSI-GIDADVPRKAASVAKLFILGEAYRRLE -SNLLSFDKLVYIDHQSMVGGSGVISYLKNAHYSYQNLIELMIIVSDNTASNALLDAI-GM -EDINHFSKSIGCQHTIIERKFMDIEAA-EKGKDNITTANDVVCLLKLFSRNDYFPNKSRR -EILRILGDQQF-NNKLSTFNPPNIRFYRKTGELQ-GVEHDAAIIEANGK-RIEAAILTEG -WK-NNGTGQHYIAEVGQLIIDY- ->[subseq from] Beta-lactamase class A n=2 Tax=Tissierella praeacuta TaxID=43131 RepID=A0A1M4S797_9FIRM ---SLESRINAEVYNFSGKMGIYLNDF-KGNII-EINSDTKFETASTIKVFVLAELYRQIH -EKKINANKILKYEKENYVVGSGILRDLDYGVMTAKSFATLMIVISDNIATNILIDLL-GI -DNINNTCVDLGLKDTILHNKID-FEKY---SKLGTTTPRDYGKFFELLYKKELWSKEISE -EMIEIFKNQHY-NTILTRDLPQYVSIASKSGSMNE-CRNDGGIVYTPYGG-YVISLFTKD -FVDNDHESYRFGGKVSRLIFDQy ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B86410 ---TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDEPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL -ASLATVIEDLGLEQTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8NYV7_9ACTN --------ARETLAAAGTTGAFHARPVGGGAEL-ALDADAAQVAASTYKIAVLLEVACQAA -DGELSLTRRVRVPGDVRSPPSGISTMLDEVELSVRDLALLMMQVSDNTATDVLQEIV-GT -ARLAARLDALGVRDTTVRLDCAGLIAALACATGNTTTARDMTTLLSLIWRDEAGPPEACE -EVRRVMLQQFA-PHRLSTAYRDGPKIAGKTGTFYGGVRNEVGVVDFGGGEEYAVAIFLRQ -HDLRDARADAAIGAVARLLVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus sp. 15-649-2-2 TaxID=2023140 RepID=A0A260R1W5_9NOCA ---TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DALARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. 34-1 TaxID=2709706 RepID=UPI0013D143DC --eKLSKRIDKIVQEYEGHLGIAIEW--KEQSF-LLNENDIFPSASLIKLPVLIEGFMQSS -SGILDLEDLVKVNSLQKTGGAGIVQYMSPQSLSIRDLLTLMIIVSDNMATNYLIERL-GM -DNVNRRCQQIGMSSTILQRKMMDRE-ARERKIENYTSPQDILRCLKSIYNDKN------Q -SGKTILDHQQL-LDKLPYYHRNGIRIANKTGELDK-VEHDCAIIEHEDET-IFIAVLTDQ -LTAN-QKGKEIIQLIGASIFE-- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb62 TaxID=1848690 RepID=A0A2S9AKJ6_9MICO ---DTAADIAEIFADAGATGFLHAREIGGGPEV-GEGADEPVVLASVFKILVLTAYVRAVA -AGELDPTERTTVTARYRIGGVGTAGFADDVVISWRDLALNMMSMSDNAATDVIYHRL-GA -AAVDRVIADLGLRHTRLIGCCEDLFAAVQPVKTSHSTPRDVTTLLDALWTDTAAPAEACR -QSRDIMAQQIW-PHRLTSGFPAGVRLAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLA-DRQ--------------- ->[subseq from] Serine hydrolase n=1 Tax=Ruminiclostridium sp. MA18 TaxID=2488810 RepID=A0A4U7JN89_9FIRM --dELEKLITDFTSKLPGKYGVTFIDLATGEMV-NVNDKIEYIAASTSKLPINVLLYKNIE -AGKIKMEDKLVYKKEDLEYGTGIIINSPYGTYTVRETSRLSIQKSDNCGVNMLIRLL-GI -ENVRNYIDEVGGQVHY--------------GKTHRSCPYDMAQIAQDLYKLYLNNEEVYG -ELINYMETTDW-SDRIDAKLPKDVKVAHKIGNQVS-TRNDVGIVFAT--HPYVLSIMSDN -VNVD--AATKAIADLSKLIYD-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00040047D8 ---------DAHLDRMPGTVSAYLASLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AGRLAPDTAVPVRNEFDSARPGAAWDQLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSNTGRGIEDLAAR-AVGITNLVTTADLAALLRGLALGALATPESCT -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG -DHSPDEDACQLIADISARAF--- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Peptostreptococcaceae TaxID=200630 RepID=U2J1X9_9FIRM ---------------------------------------FQQEPASVMKIYLMAESMEQVK -EGRLSLEDTFVMDWNNMADDAGVIESSLGAEYRLKELQEYMMSISDNTASNMIIDAIGGL -EAVNKRKEEWGLENTVFGTKYIGPGVA-PGFDYNTTTTTDVGRLLKRIANFQLLGPEYDQ -KMLDLMAKNEN-WEKIPGLFPEEIKVYNKTGELD-ALEHDAAIIETPKGR-YVLVIFLSR -GD--------------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium cuniculi TaxID=2548455 RepID=UPI001054FB23 ------KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVSMTAAGCMKLPIAVSLIKAVE -DKKVDFMDKIKIQTSDKVYGTGIIHEFNEREYTVFELMVIMLIQSDNTAANKIIDIV-GM -EQINEDIIAVGLKNTRLNRKTNDERTD-ITDIENITTAYDLSKIWKHLSNGTFLSKDNGQ -MLIDILRRQQI-KNKLALYIPDDIEISSKTGDKK-GVENDTAYLELPKGK-FVFTVLSQD -IPNS-VYGTVSLAKCGKMMW--- ->[subseq from] serine hydrolase n=1 Tax=Sporosarcina sp. D27 TaxID=1382305 RepID=UPI00046FAFEF ---QLKEELDRIAYETTGDVSIYATT--PDGVI-AIRENEVKRSASILKVPVAMACLAAAD -RGEIDLDTLLKIEE--PVGGSGVLAYMSDMEITLRNALTLSIIVSDNSAANLVIEHV-GI -ERIQNFFKHVGATHSQLTRKFMDYD-ALAQGLENVATAKDMVRFLMCLDPSENLSQTSKQ -QLKTIMRDQQL-IDKLPAFQPETLIIGNKTGTLP-GVEHDIAYFENGER-CVNIAVLTTD -WEYN-HDGQQTLAQIGKAIIKY- ->[subseq from] Beta-lactamase class A n=1 Tax=Catellatospora citrea TaxID=53366 RepID=A0A419WY88_9ACTN ----ITNRIAAAFASADMQGWLHARDLDTGREV-AVGADDQVVIGSIFKILLVLEFARQTA -AGSLDPADRVLVRAGDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLRRI-GP -DLLPLLAQELGLTRTHLIGGPRELLAVFDPARTNSSTPEEVTRLLGLIWRDEAGSARACA -DVRALMFRQLF-WTRLAAAFPPGVRVAGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAKT -ERLSMPELDLVLGRAAKLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0014032DB0 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAVDKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=Acidiferrobacteraceae bacterium TaxID=2024893 RepID=A0A2E7WRN8_9GAMM ----LENDLNQLCDEQPFHTGWYVRNLYTGDNL-QRHGDVVVPSASTRKIAIMMAALKAVS -EGGLALDQPVTMSAGYQDNDSGCFQHQPGFTIQLRDALVMMIIVSDNTCTGVVADLV-GL -ESINSLCQSIGMTGTVHRYGIPGMAGYLPAAQTNATTPADVAHLLDLILRGSGCRPESCQ -LAIDILSWQRL-RNRIPARLPLGTRVAHKTGTTAK-NYNDAGIVYFEDTPLFIISSYTDA -VEAE------------------- ->[subseq from] Serine hydrolase n=1 Tax=Plantibacter flavus TaxID=150123 RepID=A0A4U3G4M9_9MICO ----IAARIESVLEPLGVRGYVHAVDIDSGVEV-GLDADTDVVTASVFKLPVLVELARQYE -VGALDPRQRIRVGADERRTDGPTLSILLDDVLSLRDLSVLMMSVSDNRATDLITDLV-GL -DAVNATMRSFGLERTVVPVDCDALFRVSNPESNDRTTPREITTLLAAVWRDEVIGAAAAA -EVRRVLGLQAW-SHRLVAGFPSRVKVSGKTGTLFF-IRNEAGVVEYPDGGRYAVGVFLRE -SSLRHPDADRAIGTVARVAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium gasigenes TaxID=94869 RepID=A0A1H0MMD4_9CLOT ------KEIKRYLESRIGTYGFFFEDLKSGFIY-GYNENVQMVAAGCMKLPISISLIKAVE -KGKVDFMDKIKINGEDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTATNKIIDIV-SI -KQINEDLKEMGLRNTILNRKTTDER-NNNSDIENITTASDLSKIWRHLYKASYLNKENSE -MLVDILTRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIRLSKGT-FTFSVLSTN -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000976924B -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLIDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIIQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Serine hydrolase n=1 Tax=delta proteobacterium ML8_F1 TaxID=1775671 RepID=A0A1V4M4B0_9DELT ---SLEARLRAEVVSFSGHASFYANDF-KGNVI-AVNAHEQFEAASAIKVFILAEFFRQVH -EGRLDRLRLLTYDKENFVTGSGLLRHLEPGTLSAENLARMMIIISDNIATNMLIDLL-GL -ENINRTIESLGFTSTTLHNKID-FDRY---ERLGTTTPRDYGVYFEKLREGLLIAPEISR -EMLDVFKKQQY-NRMLTKDFPQYIAVASKSGSMD-AARNDGGIVFTPYG-SYVIVIFTKH -FKDPDHESYIYGARASRLIFNQ- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V9SGL1_9BACT ---SLRRELEQIRSHFPGDMSIYMKNLSTADEI-ALDSDKEYETFSVIKLAIAAELMHQVE -S--GKFSDRITTKATDERLASGALYADPGLNPTIKDLLTLMIIISDNEATDLLADKV-GR -AQVTAYMRSLGLANTAIQFSDLDWDRYDAGIFFGHSTTKETGRLLEMMASGKLVSKDASG -LVLSIMEKQQI-NDRFPRYLK-DVRIAHKTGDGQPFVANDAGIIWVNNQ-PIILVV---- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroides xylanolyticus TaxID=384636 RepID=A0A2S6HN86_9BACE ---TLEKRIQAELMSYDGKMGIYLNDF-HGNVI-TMGQDEKYETASTIKTFILACLFDEVE -KGNKSLEELVEYKPEHVVDGSGVLAALEPGALRVKDAAVFMIIVSDNIATNMMIDYL-GL -ETINSCIQKLGCKDTILYNPIH-FDRY---RQLGTSTPNDYGSVFTRLVKGELISKKADG -AMLEILKKQHY-NSMITKDFPPVISVASKSGSMD-ACRNDGGIVFTPYG-PYVIVMFHKE -FSDAAHPATIFGARVSKMVLDQf ->[subseq from] serine hydrolase n=1 Tax=unclassified Rhodococcus TaxID=192944 RepID=UPI000B9A6B00 ---TTDEQLRAVFADAGCRGWVRAERIDGPGTVvDYEGDDPVVAASVWKIVLLVATARAFD -EGSLTATDSVRLVPAQCSPPTGIASFADPVSMSWRDIARSMITVSDNAAADALLGAV-GL -DAVARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSVWLGTAASPAQCR -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=UPI0004A743FB ---------REIFRKAGVRGWVHARCFGCAGEH-GLEADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRVRAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL -DNVRSLVRELGLTGTRIVGAPRDIVQALDPRRTTASTPREMTRLLTLIGQDLAGPAQACG -WVRDVMREQVN-WYRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPDGSRYAVAVFTRT -ESQRLPEVDRAIGAAAVAAID-- ->[subseq from] Uncharacterized protein n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A2M7RP97_9BACT -----LPRIEKEIGGLGGTFSVYLYDINNNVEI-GLDENMVLTAASVNKIPILAALYNLAG -KGEIDLEKVIVIQPGDVQDTGSIRYDPPRSSYSIKTLARLMMEKSDNTAAYILGSHIVGL -KKIQNLVNSWDLTQTDMV--------------ENKSSVKDMSILMIKMYHGEITTPPLTT -EMMGFMDKSDF-DDRIPAGLPENVKFYHKTGDEI-GKIHDAGIIDLKNR-PYFLGVFTTD -MK-DEVKTKKAIANISKIVFEY- ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium 69-20 TaxID=1895696 RepID=A0A1Q3PVN5_9ACTN -----ATAIAAASADAGADVFAHAIDIDSGAGV-GVRADDPVVTASVFKVPVLTEYVRQVS -AGDLDPASRVLIRSGSATMGPTGLSVFSDDAWSLRDVATSMITVSDNAATDIVTGMV-GV -DRVNATMAELGLPGTVLIGDCRVLFDVCTPTLTNRSTPRECARLLQLLWTDRAADPAGCA -EARRILGLQVW-PHRLSSGFPDDVRISGKTGTIGI-VRNEIGVVEFPDGHRYAVAVFTRS -HRYRQPKVDALIGTVAAALV--- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0M1W6_9BACT --eKIQKEFKEKTGNLSGVYGLFVIHLDNGFSY-GVNENEIFTAASLIKLPVIAGMYMEDE -AGNIDLDEKYTLKNSDKVTGAGSLYGKPAGYTTYRNLVQLMGKQSDNTAFNICRKLL-GD -EKIDEVTRSVGMVDTSLEK--------------NETTPKDIGIFFEGLWRGNIVSQESRD -EILDYLTDTIY-EDWLPAGIPDDLRIAHKYGREVH-VVNDAGIVFTT--KPFIVVILTKG -VI--EKEADTVLPELSEIIYE-- ->[subseq from] Beta-lactamase n=1 Tax=Haladaptatus paucihalophilus DX253 TaxID=797209 RepID=E7QPE7_9EURY --dELAATIAAYDETIDGDLGVFLGFPSGPDVVcSHDETRVFQSASTVKLPVFYALYERYD -ADDDELDRPCPLSPENRVGGSGLLHL-LNATPTVEDLARAMISVSDNAATNQLIDHL-GM -SAVNDAAARLGMDRTRLARKMMTTLEVPADEPTNATTPLDCARFFADLACETTLSAAAYE -RMRVPLAAQKD-TSMVPRYLPYETDVAHKTGRLPT-AALDTGFLSVPDRRPLVFSVFIDG -VGGTETDGARATSDTGAD----- ->[subseq from] Serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=A0A0X8P1S8_ALCXX ---YVEAALAPLLAATPARVSLSLRDLDGGIVL-ARHADRQRPSASIIKIPILLALLEAVA -GGRYALEQPLVLPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIELL-GF -DEINQWSQRVGLTASPLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGALPAPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. GP55 TaxID=1798190 RepID=A0A2N3UEF3_9ACTN ---SARTRIAEAFAEAGVTGLLHARDLDAGTEL-ALGADTLVSTASVHKLCVLTTLFRHAG -AGRIDLTRRLDIPAFGRTDPTGLAAMLDAARLSLRDLAYLSIAVSDNTAADLLWDEL-GL -DAVNGTMADLGLTRTVAVHKIRDMIAVLDPAFTNRSTAREMTALLAAIWHDRACPGEHGA -ALRRLLGLQVW-PHRLASGFPDDVRVHGKTGTLPT-LRHEVGVIEYPDGGRYAVAVFTRA -TATSLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridioides difficile TaxID=1496 RepID=UPI0009432A97 --------IINKLKNMKGDVSFYYKNLVTQEII-KYNEEKPMLAASVIKLTVLVECFNQIK -KYIIRKDDIFITKEEDKVPSCGALNYMRENLITLEDLYVLMIILSDNYATNILIDKL-GI -DNINKTIKEIGLKNTVLNRKMFDSDKA-ALGLENYISAGDIAYLLEKMYNKELIDEKSSE -EMINILKNQRL-NGKVPQSIKPKVNIAHKTGEDTN-ITHDVGIVFD--KEPFIVCFCGNN -V--NVPEYERLMQDVT------- ->[subseq from] serine hydrolase n=1 Tax=Catellatospora methionotrophica TaxID=121620 RepID=UPI001408ABFD ----ITNRIADAFAAADMRGWLHARDLDTGREV-AVGADDQVVIGSIFKILLVLEFARQAA -AGSLDPADRVLVRAGDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLQRV-GP -DLLPLLAQELGLTRTRLIGGPRELLAVFDPARTNSSTPEEVTRLLGLIWRDAAGPAQACA -DVRALMFRQLF-WTRLAAAFPPGVRVAGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFART -ERLSMPELDLVLGRAAKLAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces chryseus TaxID=68186 RepID=UPI00110F902E ------ERIREVFAGAEGVLHAVAVDTEPGTQEvAVGADGPVVIASVFKVLLVLEFARQVT -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL -DTVRLLAGELGLPGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA -HVRELMARQVF-RHRLVSGFPDEVMVAAKTGTLP-GLHMEAGVVRYPDGGRYAVSVFART -RGASRPAVDAAIGATARIAVD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Brevibacterium casei TaxID=33889 RepID=A0A449DBT8_9MICO ------DEINGVWTSLGAQGFLFAEDLETHRSV-GIRESARIPLASVGKVAIVAGLLDAAA -DGVLDLTRRVVVDPTTATPGTGISGLHDPVEMSLRDLAAMALSVSDNAAADTLFALV-GP -ERITALLHRFGIRSFDVVAPMSHLYDQLPDSAFNTGTVRATARLFELIHTGRLLGAEDSA -VLRDLLRRQIF-RHRIAAGFPDAVSYYGKTGTFLN-FRHEAGVIVDSDGAAYSIAIFTRS -TIATQPELDASIGYCARLAIEH- ->[subseq from] serine hydrolase n=1 Tax=Jiangella alba TaxID=561176 RepID=UPI0009F39667 ----------------GVTGFLHAADVGSGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA -TGERAPADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -EKINAGTAALGLTGTVLEEDCAGLFRVLDARTTNRSTPRETTTLLRRVWTADGLPAAACD -EIRRILALQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL -PGAENPAADAVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000E59F39F -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNKAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces auratus AGR0001 TaxID=1160718 RepID=J2K8Z7_9ACTN ----TQDHIRTAFADAAVTGWLHACDIDTGAEV-GFHPDHPVVTASVHKLCLLVALHQCAA -QGDFELTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL -DAVNRTTTQLGLSHTLAIHTFQQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA -AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154MP61_9PSEU ----VVETINDRAEEVGVRVRLHAAEIDGTRRI-GIDADTPVVTASVFKVPVALELARQAA -EGELDLGERITVVPGHPTPPYGLATFRHEVTMSWHDLAILMIGISDNVATDLILDRV-GP -EATGETLRRLGFEHTIVSQDCGEILGALQPAHTCATTAEEITRLLTLIWRDEAASPAACA -DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAARA---- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI000C1259F6 ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0013748BB3 -----TDLVAQATNGLAGQTSLAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6SLA9_9BACT --------------------------------------HRRFKAASVVKIPLMIEVYRRVE -RGELRLDERHVLAARDKAAGSGVLLHHPGLTLTIEDLVYLTMSISDNSATNILIRRV-GM -DRVNATMQGLGMTESTLGREMKGRV-AEPGEAENWATPGDYVRAVRAILDGEAAGPAGCA -AMVAMLERQQN-PRRIGRYVPEGVRWGSKTGGLK-GVTNAV------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Euryarchaeota archaeon RBG_13_61_15 TaxID=1797978 RepID=A0A1F9ZKR9_9EURY ----LRADIIKAAKEVKGQMGLYLKHVESGSEV-AIDADKTYPLASVFKLAVMVETYRQVE -DGLISLDERIELEPRHYCIGEGVLQYLSPGLPTVQDLLALMILETDNTASEMLWKRI-GI -QRVGMLMKELGLAKMSI------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces luteus TaxID=1915400 RepID=A0A086N748_9ACTN ----------------------AAGEWTAADEV-AVGADEPVVIASVFKVLLVLEFARQVT -AGQLDPRARVRVTAADRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLAEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLCLIWRDEAGPPQACA -QVRDLMSRQVF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -REASRTAVDAAIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Halobellus captivus TaxID=2592614 RepID=UPI000EFC3526 ---DLAGAIDSIADRFDGRLGVFLGVPRGADAFhRRNADEEFVSASVIKLPILYALYEEYD -GRLERLAETRPIAPENRVGGSGLFHLLDRPTPSLEDLARAMIAISDNAATNELIDAL-GA -ERIESAATRLGMTNTRLRRKMMATLGLPDNGPANVTTPTDCARFFADLVHEATLSPAAYA -RLRVPLDEQKD-RSLFARFLPYRTPIAHKTGGLPT-AAIDVGVLRPADVSPLVFSAFATR -AGNG-GDASDAVAAVGEAAFE-- ->[subseq from] Uncharacterized protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A349BYU1_9FIRM ------------------------------------------------------------- ------------------------------------NTVRNMIVYSDNEACNKLIDLV-GM -KNINQFIQNKGFSKTRLNRKMLA------KGEENYTSAKDCARLLQAVLNGKFVSSGASA -SILKYLKAQTR-TGKIPAGVPSGVKTANKTGELAY-TENDAAIVWGKKG-PYIIVILSDQ -VGAPG-KARTAITNMSRITYD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI000932E8E9 -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTLVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Desulfofundulus thermosubterraneus DSM 16057 TaxID=1121432 RepID=A0A1M6G769_9FIRM ----LQNQLKDYLAQQPGVYGIYFKDLHSGASF-DINGDEPITAASTVKVPVVLYLNHLVA -QGRLEWDDRVVYDSKDYQGGAGILQFSARDGYSLRILANLSITISDNIAYRMLVRHL-GK -DNVAQFMRDLGGQTV------------FPG-GENITTARDMGRYMEAVLEFSRKHPALGE -RLLDDMANPIY-HVGLPGRLPPEVRVAHKEGDVW-GVANDAGIVFAE--HPYILVVLSKG -ET-DVDKGFARIAEISRMVYDY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces europaeiscabiei TaxID=146819 RepID=UPI00067CB6BE ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDLRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. OF04-11AC TaxID=2293109 RepID=A0A373NWG9_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS -RGKASLTEEIEYRPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL -ETINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPERIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD -FH--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis rubida TaxID=112413 RepID=A0A1I5JD50_9PSEU -----RARIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMSDNAATDVLYHRL-GQ -EKVDRVLADLELARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPQACE -RVRTIMAQQIW-PHRLSSGFPPGVAVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -QSDRLPAVDASIGAAARLALDH- ->[subseq from] Uncharacterized protein n=1 Tax=Armatimonadetes bacterium TaxID=2033014 RepID=A0A3D1I8U3_9BACT --qALAEELNAHAERLRGTAGFWVEELRGARSA-GRLADRPFPTASTIKTALMVAVLREVE -AGRMAWTETLPVPPPDRRELSPWSWFFPEGQIDVDGWVNLMIGYSDNTATIVLRDRV-GT -ETINRMLEELGFRHTRFLSGTPPLAELRATFGLGVTTPREMARLLKGIALGHWAGPAASE -RMVRILSHQYW-DNLIASAVPPCVLCASKSGFVAS-SRSDTAIVFGP--TPYVAAFYTSD -LCGPNNEAVRWIREASGIVW--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003682755 -----------HLDRMPGTVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRDLA -AGRLTPDTAVPVRNEFDSARPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AAGITNLVTAADLATLLRGLALGALATPESCA -AMLDLLVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTD -DRSPDEVACQLLADISARAFA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis tolypomycina TaxID=208445 RepID=A0A1H5A6T0_9PSEU --------LAAFFEAVGVRGFLHARRLGSAESL-GCDADAPVVLASVVKVPLAFEFARQVA -AGLLDPTDRVHASAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTSVIGAPRDVLRALDPLRTSATTPREMTALLAALWADEAG-----A -PVREWMTAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVARYPDGAEYAVAVFTVG -GAETRPDIDRAIGQAARAAVDQ- ->[subseq from] Uncharacterized protein n=2 Tax=Firmicutes TaxID=1239 RepID=A0A1C5NRB9_9FIRM ---------------DKAAVSLYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDAAYPVYGN--VEGGSFYDLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAVNEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE -AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Rhodococcus sp. 06-412-2C TaxID=2022487 RepID=A0A260AB43_9NOCA ---TTDEQLRAVFADAGCRGWVRAEWIDTGTAV-DYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DALARVIDDLGLEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPAQCR -YMKGVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPLOWO2_01_FULL_39_10 TaxID=1798622 RepID=A0A1F6KLB2_9BACT ----LKHIVESNFSKEKGEWAVVVKNLKTGESF-KYNGNQKFDSASLYKLWVMAVAKGQIE -NGNLNEGTLLSAEKEKLDELSTVTEEFKKEIMTVSDALEKMITISDNYSALLLSARV-GP -SNITSFLKDYGFDNSNYAS---------PP----ETSASDIAEFFELLYKGEIVSEKTSI -EMIEILKQQTF-DDRIPKYLPKNTEVAHKTGELF-GAKHDAGIVFSKGGD-YIIVVLSKT -EN--EKEAAEKIARFSEEIYKYf ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. 27_14 TaxID=1896979 RepID=A0A1Q6LFN8_9CLOT ------------------------------------------------------------- --------------------------------------IKLMITQSENFATNRMIDRL-GF -DKINNYIRSNGYTNTELNRYMLKSNAN----GDNYTSSKDAAKILENIYNHKCVSYEASE -QMMAYLKAQQL-RSKIPDGVPSGVQTANKTGELDT-VENDAAIVFKDN-APYVLVVMSSG -LSD-TAKARQNIVDISKIVY--- ->[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52909 TaxID=2653851 RepID=UPI00140991B7 ---DLHQKLKRIADAYPGRYGVVVSDPSTGQTV-SMDPDGRFLAASLNKLPVLMTLYRSAA -AGTVDLDDEISMQASDVQAGTGSLYKPIGYTLTLRECAAFLIKESDNTAWKMLDRYL-GR -DYIRSELQRVGASTTE--YWIP-----------NTTTPNEILIMLEKIADPSYTSPELSA -EMLDLMKNTDF-EDRLPQPLPKGAEVSHKIGSYG-ATFGDAGLVFPKGSDAYFIVVMVDE -TGE--GTARAAMQEMSLASYKTf ->[subseq from] serine hydrolase n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=UPI0004799558 -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ -EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI -DKINDDIEAQGLKNTRLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYNSNFLDEKNSK -MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces viridosporus TaxID=67581 RepID=UPI0009BDF46C ------------------------------REV-AVGADDPVVIASIFKVLLVLEFARQVV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GP -DTVRLLAKELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWSDAAGPPEACA -FVRDLMSRQVF-RHRLASGFPDDVAVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -RDVSRAMVDAAIGRAA------- ->[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium KBS 89 TaxID=1267534 RepID=UPI0004BC8FBA ----LPAQIHAIEAEHHGDVALFAENLKTHETV-ATSPDTPVQTASVIKLAILYEALEQVR -SGKAHFDDRVTLTPADQVPGSGVLRLFDAPLLTLKDVLTMMVVMSDNSATNLAIDHL-GL -ENIDDRIAKLGLKDTYLYKKIFTPAPAMPTDQKGKTTAREMATLMTKFVRCELAEPASPT -QSEDAMLRLQFYRSAIPRYLDASDSIANKTGSLD-AVRNDVAAISTKNGIVIISAFTFNN -KDHSEQEGELTIAKLAKAIIQSw ->[subseq from] serine hydrolase n=1 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=UPI000B8536C7 ----IEKRIAEVFAEADAEGRLHAVDIDPGREI-GLGVDDQVVIASVFKILLVLEFARQAD -AGQLDPRERVVITAPGRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALVRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLA---- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora alkaliphila TaxID=1783498 RepID=UPI0013B8C87C ----------------------------PGREI-GLLPDDPVVLASVFKLPLAVAFARAVD -DGRLDPTEPVTLSPDTRTPGATGFAAMSDPVISWRDAVRSMMTVSDNAAADALLDAL-GT -DDVNSTLAELGLTSTRVSGGTRHLYADPHLTTSTVGTCRDMTALLESVWHDRAASAEQCA -FIREVMAQQVW-TQRLAAAFPDDVVVAGKTGTFL-ALRHEVGVVEYPNGEAYAVAVFTLS -TRARLPGADAAIAQAAKLAV--- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora sp. XMNu-373 TaxID=2650750 RepID=UPI001391D0E1 ---------AKIERSFGVFGCLHATDLHDSREV-SFQADEQVVLASVFKLPLAVAFARMVD -AGEIDPLATTTFDPAQRTPGSTGIAAMTDPVLSWRDAVRSMMTVSDNAAADALFDLV-GA -SRISAMLADIGLTATRVVGGTRDLYADAGRAANNVGTCLDMTKLLEAVWQDRAASSEQCA -FLRSVMAQQVW-TQRLAAAFPDDVVVSGKTGTFV-ALRHECGVVEYPNGEAYAIAVFTLS -TRGRLPSADASIAHAAKLAVA-- ->[subseq from] Serine hydrolase n=1 Tax=Dethiosulfovibrio peptidovorans TaxID=47055 RepID=A0A2G6M2X1_9BACT ------------FEAFGATAGLVVSVHGSNFRW-SHNDSRVFPSASLIKLAVLWSLFKGSD -RGLWSLEDEIDILGDQIVEGGLLHRRAPGGSLRLDDIALLMIAVSDNTAANLLIDHI-GL -ERINEDIGLLGLKETVIGRKMMDFESK-KIGKDNYTSPRDMEKLIRSLTLEDMFPLR--E -RALDMLSCQKL-NSKLAGEIPLEGFLAHKTGELP-GSEHDCGVFFHKENNPIIVTVLTEG -LANP-CLGIELCRDVGRVVYNTf ->[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. MH-G8 TaxID=1854588 RepID=A0A263DU19_9PSEU -----AERVRAVLEAADADGAVHVRRIGGPQRF-ALAADRPVPSASVFKILVLLEFACQVA -AGTLSPTTRIRVPADERTMPTGLSVLRDDVEMSARDLAVLMMQISDNTATDVVQRLV-GT -ASVARRVAALGLTATVVEHDCRDLLASLRAECGNRTTAREMTALLELIWRDEAGPAQACA -ETRRVMGLQHA-PHRLSTAYADGPVISGKTGTLV-GVRNEVGVIDFGAGEQYAVAVFLRG -RTQRDPAVDRAIGQVARIVVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI001374D0B8 ----IEKRIAEVFAAADAEGRLHAVDIDPGRQL-GLGVDDQVVIASVFKILLVLEFARQAG -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGPPAACA -LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Cnuella takakiae TaxID=1302690 RepID=A0A1M5F893_9BACT -------KIVALAQGFNGSIGIYVKDLRSGKTV-SLNADTIFPTASIVKIPLAVGIMDKIG -KGELSYHQELVYNDTILYPGVDILGSYKNGEVELSKVLMLMLTTSDNTASLWLQQMAGTG -TRVNTLMDSLGFPELKVNSRTPGREATRAVYGWGQMTPRAMASLLENIYRRQLLSQAASD -RLLRSLNRNYW-DGEALSQIPPYAALFSKNGAVD-ASRSEVVLVRGRKS-EYLFCIATKN -NKERGNEAWVLTRKLSAMLWDHf ->[subseq from] serine hydrolase n=1 Tax=Agromyces sp. HY050 TaxID=2651191 RepID=UPI0012ECF15F --qALRERIGSIEAELGVTATMHAIDIDTGEEF-GVAADDLVVPASIFKVPVLTELCCRFA -DGSIDPAQGMFIAREAFRTGDTGLSVFLDDVLSVRDLAVSMMSVSDNRATDILIDLL-GL -DAINERSRRLGLEQTVLVEDCAGLFRVLDASATNRTTPREVTASLALLWDGGVLAPAATA -EARRILSLQVW-PHRLKAGFPSRIRISGKTGTLPY-LRNEAGMIEYPDGGRYAVAVFVRE -TLEENIDADRSIGLIGRAVVDE- ->[subseq from] serine hydrolase n=1 Tax=Acidisarcina polymorpha TaxID=2211140 RepID=UPI00123822C8 -------------------------------------------MQSAFKFLLNVAVLHAVG -QGKLSLEQSVHSLPSDTYKFSPLQDMYPAANVPLRQLPELWVGHPDNTANDILLRQMGGT -APVQQYLDSLGLQGIQIRDSEASMHDDERRQYRNTGEPATFVKLLCMLAENSLLTHGNTK -YLLSIMSSSPSFPNRICGLLPAGTIVAYKTGTAGYNATNDVALITLPTG----------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Bacillus hwajinpoensis TaxID=208199 RepID=A0A4U1MLZ0_9BACI ---QVSERILDCFRSLEGNQSLYVLAP--DGEI-ALNEDQPVSSASIIKLAIMIAALRKVD -NGELNFNTVIPIESSNKVEGAGVISFLSNDLWTVSDLIKLMIVSSDNTATNQLIELL-GK -DEINHTMKCAGAFHSKLMRKMMDWEA-VKDGRDNMISSKDIYLLLNELVTEHLLSKSSME -WGITVLMQQQL-KDKFPAKIAQNNVLAHKTGELP-GLEHDSGILFTSKG-PVIYAFLTAG -LI-ENRYGRDAISNAGRLLYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora rhizosphaerae TaxID=568872 RepID=A0A1C6RTH7_9ACTN ----AEEEVTEIFSRAGVTASLHVMAVEPGREV-AVRADEQVVIASVFKILLVLEFARQVA -AGQLDPVERVLVRAEDRLGGWGTAGCSDDAELSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELELPRTRIVGGPRQLVEVFDPAHTTSSTAREMTRLLGLIWRDEAGPPAACA -MVRELMGRQLF-WTRLPSGFPPGVHVAAKTGTLP-GLHLEAGVAEYPDGGRYAMAVFART -ERLSRIEVDLAMGEAARAAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V2RQ23_9BACT -------------------------------------------TMSVIKIPILVESFQQIQ -DGKFKLDDRLEWNDPKRRWGTGLLQILDSGMPTIRDYMTLMITLSDNSATDVMLEKIGGP -AAVDASMKKLGLKTIHCPGTAYDWFLSEEKNPFGLASPRDIGKLLEMIVKGEAVSADASK -KMIEIMRNQFY-MSRIPHYLPDPWSVPHKTGDFPPYLANDVGILEPGKQ-RVVIVVFNSH -FQGQYPLLEDAVAKIALEAYRFy ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A3D1RW74_9GAMM ----LENDLNQLCDEQPFHTGWYVRNLYTGDNL-QRHGDVVVPSASTRKIAIMMAALKAVS -EGGLALDQPVTMSAGYQDNDSGCFQHQPGFTIQLRDALVMMIIVSDNTCTGVVADLI-GL -ESINTLCQSIGMTGTVHRYGIPGMAGYLPAAQTNATTPADVAHLLDLILRGSGCRPESCQ -LAIDILSWQRL-RNRIPARLPLGTRVAHKTGTTAK-NYNDAGIVYFEDTPLFIISSYTDA -VEAE------------------- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429CVH5_9PSEU ---DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ -ETICRVVADLGLTRTRMIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE -RVRAIMAHQIW-PHRLSTGFPSGVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA -HSDRLPEVDASIGAAARLALDH- ->[subseq from] Serine hydrolase n=2 Tax=Streptomyces TaxID=1883 RepID=A0A0X3WRB9_STRVO -----EKRIAEVFAAADAEGRLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAG -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLGRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] Peptidase S11 family protein n=1 Tax=Flavihumibacter petaseus NBRC 106054 TaxID=1220578 RepID=A0A0E9MXD4_9BACT --kKLEARIRPLLENFPGDAGIYVKNLRSGKTV-NIAADTVFPTASMIKIPILLGIMKKLE -KGELYYHQQLVYKDSLLYEGEDLLGSFKSGEIELSKLLLLMASMSDNTASLWLQSLAGGG -IRINQLLDSLGFVSTRMNSRTTGREAFRNIYGWGQTSPKEMSALLERIYRDALVNDTLKD -RMLRTLSRNYW-DEEALSQIPPEIQTFSKNGAVD-ASRSETVLVMAPHG-PYLFTVMTKN -LSQSNNPGWILARKLSRLLWEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis sacchari TaxID=115433 RepID=A0A1I3UH62_9PSEU ----------EIFDTAGVQAWAHVRCLDCGAET-GLDADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRATAPTRLGGAAIAGCADDVELSLRDAALFALTLSDNTAADLLFDRV-GL -DNVRSLVRELGLADTRITGAPRDVVTALDPSATNASTPRDLTRLLALIADDRAGPPEACA -WVRDLMSRQLN-WHRLTAAFPPEVAVWGKTGSLP-ALRNEIGVVSYPGGPRYAVAVCTRA -EVGRLPHVDRAIGEAARQAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Ruminiclostridium sp. TaxID=2053608 RepID=A0A3B8JCC9_9FIRM --eALKKEIEEYISQQSAKYGMYFINLVNGDEF-GINDKDEFVAASTTKLPMNLLLYKKIA -SGEIDPESTLIYLEEDFEPGSGIIQKSEGTEYTVRETARLSIVYSDNCAINMIIRLL-GI -DNIRNYMQELGGT--------------IYYGRRHRSCPYDIALYTKELYRFYIESPEIAG -ILIDDLQNTVF-NDRINKYLPEDVKVAHKIGSFEYGVYNDVGIIFAD--EPYVLAVMSDG -AE--YGAACDVIGEISKRIYY-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193BY81_AMYOR ---DIRERIEAVFAAAGAEGSLHAREVGDGAEV-SAGADDQVVLASVFKIPIALAYAKEVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRL-GQ -ETICRAVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTALLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVRIAAKTGTLP-GIRNEAGVLTLPEGRRFAVAVFTRA -HSLDLPEVDASIGAAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces kanamyceticus TaxID=1967 RepID=A0A5J6GM73_STRKN ---DVNEQIATVFEEAGAQGFLHAREVGPGTEV-AFGADAPVVLASVFKIPVAVAYAREVA -AGRLDERERTTIPARYRIGGIGTAGCADDVEMTWRDVALFMLTMSDNAATDVLCHRL-GR -VTVEKVLAELGLSRTRLTGCCEDLFAVLDPARTSASTPRDITELLDAIWTDRAGAPEACE -RVRSMMRRQIW-PHRLTSGFASDVTIAAKTGTLP-AVRNEAGVVAYPDGRRFAVAVFTRA -ATLDLPAVDASIGRAARIAVDH- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4SS22_9PSEU ---DIRERIEAVFAAAGAEGSLHAREIGDGAEV-SAGADDQVVLASVFKIPIALAYAREVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWDRI-GQ -ETICRVVADLGLTRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE -RVRAIMAHQIW-PHRLSTGFPSGVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA -HSDRLPEVDASIGAAARLALDH- ->[subseq from] serine hydrolase n=1 Tax=Clostridium gasigenes TaxID=94869 RepID=UPI0014384691 ------KEIKRYLESRIGTYGFFFEDLKSGFIY-GYNENVQMVAAGCMKLPISISLIKAVE -NGKVDFMDKIKINGEDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTATNKIIDIV-SI -KQINEDLKEMGLRNTILNRKTTDER-NNNSDIENITTASDLSKIWRHLYKASYLNKENSE -MLVDILTRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIRLSKGT-FTFSVLSTN -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Agromyces sp. HY045 TaxID=2651190 RepID=UPI0012ED9C5D --qALRERIGSIEAELGVTATMHAIDVDTGEEF-GVAADDLVVPASIFKVPVLTELCCRFA -DGSIDPAQGMFIAREAFRTGDTGLSVFLDDVLSVRDLAVSMMSVSDNRATDILIDLL-GL -DAINERSRRLGLEQTVLVEDCAGLFRVLDASATNRTTPREVTASLALLWDGGVLAPAATA -EARRILSLQVW-PHRLKAGFPSRIRISGKTGTLPY-LRNEAGMIEYPDGGRYAVAVFVRE -TLEENIDADRSIGLIGRAVVDE- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-118 TaxID=1463881 RepID=UPI0004C63312 ----------------------------------GLGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVLVRAEHRLGGWGTAGCADDVELSLRDLAFFALSVSDNTAADLLLERV-GP -DTLQLLAGELGLPRTRIVGGPRQLLEMLDPARTNASTPREITRLLRLVWRDEAGPAEACA -FVRELMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHIEAGVVTYPDGGRYAVAVFART -PDTGRTATDSAIGRAARLAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2572 TaxID=2512223 RepID=A0A4R2GZ69_9ACTN -------------------------------------ADGVVPMASVYKLPLLAAFCRLVD -LGEIDPLSRLTLDPAERTAGPTGLSVLADPVMSLRDLAVSMMTVSDNASADALLDLV-GL -RRLAELLQSFGLQRTWVRRGTAANLRVYEAANASASSPRDMTLLLQRLWAGELLSAGQTE -FVKATMHRQVF-QHRMAAGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAIAVFTLA -ARGDQPRVDTAIGEAARAAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. ARS1019 TaxID=2024878 RepID=A0A2D6Y367_9SYNE ---ALSNRWAALAANQDLKASAFMHVLDTGRYA-DFNADQPMAAASSXKTPIXLCALQLID -DGTLHWNEPLTLTKELVGGGAGWMATRPVGSFPTYEVATEMIRXSDNSATNLLIGRVGGQ -DAINMQFLELGLDATEVNNWLPDLDGT------NTTSAKDLSRSIALVDSGEVLSPRTRD -LFRAVMATSVT-NTLLPTGLMRGYRVLNKTGDIGI-AYADAGLIELPDGSRAVAGFMVEG -PFN-DPRSTELIRQMAAAMAS-- ->[subseq from] Beta-lactamase SHV-24 n=2 Tax=Planctomycetes bacterium Pla163 TaxID=2528008 RepID=A0A518D0T5_9BACT ---ELAARLEALFEPFEGRVGLYVARLDTADAF-AFDADATYPTASLVKVPILLALYERIE -AGELDPHALLTYDAQRSRGGEDLLASFQDGAITLSKLIHLMIAFSDNTASVWLQELAGGG -AGINAWLAEHGYEHTRVNSRTAGREDDYRAFGWGQTTPREMARMLASIRRGEAVGARADE -EMYRVLCRTYW-DSEALSALPPWIQAASKQGAVNR-SRSEVVLVNAPSGD-YVFCLITAD -QVDTDNTGFVLLRDVSRVLWEHf ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora arborensis TaxID=2116518 RepID=A0A318NTR8_9ACTN ----------------------------GAREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRELVEVFDPAQTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DEPRRIDVDLAMGQAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis saalfeldensis TaxID=394193 RepID=A0A1H8YKT2_9PSEU ----------------------------------GFGIDEPVVLSSVVKVPLVLEFARQAA -AGQLDPRDRVRARAADRLGGAGSAGCADDVEYSLRDAARLAISVSDNTAADLLFDRV-GV -ENVRSLTAELGLAGTRIFGSPRDVLRALDPACTSAGTPREMTELLSLIWRDEAGPPSACA -LVRDLMGRQVN-WHRLTAGFPAEVAVAGKTGTMP-GLRNEIGVASYPDGTDYAIAVFTRG -GSENEPAIDRAIGEAARTAVEQ- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chitinophagaceae bacterium TaxID=1869212 RepID=A0A4Q6AA12_9BACT ---GLQRQVEEAIKGFNGDIGVYIKNLENGKIV-AVNADTVFPTASMVKVPILVGVMHKVE -RGELTLDSNLVYRDSLLYAGVDILGSLKQDEIALGKVAMLMLTMSDNTASLWLQTLAGTG -TRINEIMDSLGLKVTRVNSRTPGRENIRSIYGWGQTSPREMATLFERIANGEVINKQRSD -AMLRMLSRNYWDKH-AISQIPA-------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Gordonia westfalica TaxID=158898 RepID=UPI0012B84FE2 ---RVDREVAETLADAGCSGWVHATTIGSPQIEySFDADAPVVLASVYKLAVLISLCRSAD -RGDIDLASSITVDPTLWAQGPTGLAAFGDPVLSRRDLAISMMTVSDNVAADVLLDEL-GL -DRVREDLVSLGAERTRIVGGVAELHEAYDAAYSSSSTPRDCTALLSAVWTDRAASPEMCA -FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTAR -SEQSLPQVDRAIGEAARTVVT-- ->[subseq from] serine hydrolase n=1 Tax=Nakamurella lactea TaxID=459515 RepID=UPI000421A15C -------RIQETFAAAGADGFLHAREIGDGPEI-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDPTERATVTARYRIGGIGTAGSADDVEMSWRDLARFMLIMSDNAATDVVFHRV-GQ -PAVDRVLEDLQLSRTQILGCCEDLFAALDPARTTSSTPREMSALLAAIWTDRAAPADACA -IVRDLMAQQIW-PHRLTSGFDNGLQLAAKTGTLPT-VRNEAGVVTYPDGRQFAVAVFTRA -HSLDQPAVDASIGSTARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis ruanii TaxID=944491 RepID=UPI000E235436 -------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVTAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEIGVAEYPDGARYAVAVFTRA -PTSRLPDVDHAVGAAARAAIE-- ->[subseq from] Beta-lactamase class A n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H5MG24_9ACTN ----TQDHIRTAFADAAVTGWLHACDIDSGAEV-GFHPDHPVVTASVHKLCLLVALHQCAA -QGDFELTEQIEVPPTGRTFGLTGLGAMLDPAVSLRDAAYLMMSVSDNIAADLLLERV-GL -DAVNRTTTQLGLSHTLAIHTFRQLLDALDPARTNRSTPRDMTRLLSCIWRDEAGTPDHGA -AIRRLLGLQVW-PHRLASGFPDDVHVAGKTGSLPT-LRNEVGVVEYPDGGRYAVAVFTRA -ANATLPAADAVIGTAARIAVD-- ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Thermoanaerobacterium saccharolyticum TaxID=28896 RepID=UPI0005F05693 --qQLKDNIETLLSQHTGNYGVYFIDLNSGETF-DINGYGSFIAASTYKVPLNFYVYTLIT -EGKLDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY -DNYLNFIESLGAYVVPY--------------SDNVTSPRDLSIYMEDILNYANAHSSTAG -ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYPQK-PYILTIMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. 06-1460-1B TaxID=2022501 RepID=UPI000B9B59FD ---TTDEQLRAVFADAGCRGWVRAERIDGTGTVvDHEGDDPVVAASVWKLVLLVAAGRAFD -EGSLTATDSVRLVPAQCSPPTGIASYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL -NALTRVIEDLGLEQTRIVGGTKTLGDGFDPAYTSCTTPRDSNTVLRSIWLDAAASPEQCR -YMKEVLSQQVW-PHRIRSGVPPDVQVSGKTGTIGP-IRNEVAVVSFPGEKPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces melanosporofaciens TaxID=67327 RepID=A0A1H4T0C8_STRMJ ----IEKRIAEVFAEADAEGRLHAVDIDPGREI-GLGVDDQVVIASVFKILLVLEFARQAD -AGQLDPRERVVITAPGRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALVRRI-GL -DTVRLLAAELGLDRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGSPAACA -LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLA---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI00069AB418 ---TAEARIQEAFDAAGVRGYFFAREIDGDRTL-GVAADEPVCLASVFKIPVALAYAREAA -AGRLVRTERLAVDPRYRDGGIGTAGCADPVEMSLRDLVHMMLTMSDNAATDVVLERV-GL -DTVNGLLRELGRDRTHLVGGCLELTGVCVPERTTRGTARDIAELLAQIWRDEAGPAEACA -EVREVMSHQIW-PHRMGSGFDDGYRLAGKTGTLP-GWRNEAGVVEHTDGGRWAVSVFTWS -RTPDNPAADRVIGTVARLAVDE- ->[subseq from] serine hydrolase n=2 Tax=Veillonella sp. VA137 TaxID=741828 RepID=UPI000F8ECCC1 -----------------------------------VKQSRPVRAASMIKVYILGYLFEEIE -AGHINLGETMELEESDKVGGAGVLSGAVGTKLTVDELAKLMITVSDNSATNILIRRL-GM -ESINQYIIKNGFMDTKLQRYMMDLE-AIRQGRENYTSANDLGHWFMNLLEGKGMSSSSRE -KMLMYLLGQTD-TETFNEALS-NRFIAHKTGELA-GVYHDGGIIFQSKGEAYILITLSD- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=A0A285IPZ0_9ACTN ------------FDKVGAGAHAHVVDIDTGHDV-GARPDEQVVIASVFKILLVLEFARQAV -AGQLDPTERVLVRAADRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRI-GP -DVLPLLTAELGLTRTRLIGGPRQVLEVFDPEHTTSSTPREITRLLGLIWRDEAGPAAACA -MVRDLMARQMA-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFART -PRTRQIDVDLAMGEAAHAAVE-- ->[subseq from] LysR family transcriptional regulator n=1 Tax=Propionibacteriaceae bacterium NML 061049 TaxID=2016501 RepID=UPI000B97AA46 -----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD -AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA -DRVQHLLRQLPPDQIRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA -AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL -QQETSHHRDWAIGETARLAVN-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RBG_16_34_12 TaxID=1802480 RepID=A0A1F7X9W0_9BACT ----VISNFRQITNNLSGVYGFYVTDLETGLSY-GVLEEEVFQAASLIKLPVMVAMYLEEE -EGSLSLSSKYKLKKSDKVAGAGSLYSKPEGYISYQELIRLMAKQSDNTAFNIARNLL-GD -GKIDEIINKIGMTKTSLQKN--------------ETTPEDIGIFFEELWNGHIINSQHKD -ELLDFMTDTLY-EEWLTAGVPVDVRVAHKYGREVH-VVNDAGIVFAD--EPFVVVIMSKG -VV--EKEADEIFPKLAKEIY--- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus siamensis TaxID=480071 RepID=UPI000984B0D4 ----LQTKIRELLNGLESQFSLYIST-KDG-DI-KISENVQRPAASLAKIPILIEALRQID -DGRLREDCSVPIKKSMLAGGAGIIAKLTNADFTYRDLLELMIIISDNTAANVVLEAV-GA -EQVNRFCSVCGCNNTILQRKFMDEA-AQMTGRDNYTSAEDMMRMLHLICSNKFISRKNRN -KIIGILSNQQL-KDKLAYYLPEDVHMFHKSGELA-GVEHEAAILEYNGNQ-LQAVVLSEG -WE-NNGDGKLFIAEIGRLLIRY- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Chloroflexi TaxID=167963 RepID=A0A5N9ES26_9CHLR ---ELINRMNAMCSESPFQSGWYLKNLQTNESA-NYYGDVVVPSASTRKIAILMNAMKWIH -EGKLSLDQPIRIDETQYVGNSSGCFQYLRPGVQLYDVLTMMIIVSDNTSTGIVANLL-GL -DSINEFSQSIGMIGTTHRHKLPPLDLDHSLDYTNSTTPNDVGLILELILLGTGSSKELCQ -IALDILLNQKL-NNKLPALLPKGTKVAHKTGTGAR-NYNDAGIIFLDDSPLFILTVFTEN -VPTSLADG--------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N6APJ0_9ACTN ------------------TVGAAGDPAGGGREV-GVRADEQVVIASIFKILLVLEFARQVV -AGQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRDLVEVFDPSRTTSSTAREITRLLTLIWRDEAGPAEACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DRPRRIDVDVAMGHAART----- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. ANT_H53B TaxID=2597357 RepID=UPI0011EE48C4 ---TTDEELRAVFADAGCRGWVRAERIDGTGTVvDFEGDDPVVAASVWKIVLLVATARAFD -EGVLAATDSVRLVPAQCSPPTGIASYADPVTMSWRDVARSMITVSDNAAADALLGAL-GL -DALSQVIDSLGLEDTRIVGGTKTLGDGFDPAYTSCTTPRDSNAVLRAVWLDTAASPEQCA -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEAPVAVSVFTRA -ARMDLPLVDQAIGHAARVAV--- ->[subseq from] Peptidoglycan-binding domain 1 protein n=3 Tax=Thermoanaerobacterium TaxID=28895 RepID=W9EBW6_9FIRM --qQLKDNIETLLSQHTGNYGVYFIDLNSGETF-DINGYGSFIAASTYKVPLNFYVYTLIT -EGKIDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY -DNYLNFIKSLGAYVVPY--------------SDNVTSPRDLSIYMEDILNYANAYSSTSG -ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYPSK-PYILTVMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=A0A1H5QBT7_9PSEU ---KVEQRISDAFLAAGARGFLHAREIGGGGEV-AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVGPRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ -EAVDRVLTDLDLHRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAGDAAACE -RVRTIMAQQIW-PHRISSGFGSDVRIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. HBUAS56017 TaxID=2571128 RepID=UPI001177D591 ------KEIKRYLESRIGSYGFFFEDLSGGFVY-GYNENVQMVAAGCMKLPIAVSLIKAVE -DKKVGFMDRIQIKREDKVFGTGIIHEFDEREYTVFELLVAMLIQSDNTAANKIIDIV-GI -DVINTDINKMGLRNTSLNRKTNDER-NRKNNIENITTAYDLSTVWRHLYKGTFLNKKNST -MLVDILRRQQI-KNKLALYIPDDFEISSKTGDKK-GVENDTALIQVQKGT-FVFTVLSSC -IPN-SVYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Actinoplanes atraurantiacus TaxID=1036182 RepID=UPI000BE2FAEC -------------DKVGAGAHAHVVDIDTGHDV-GARPDEQVVIASVFKILLVLEFARQAV -AGQLDPTERVLVRAADRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRI-GP -DVLPLLTAELGLTRTRLIGGPRQVLEVFDPEHTTSSTPREITRLLGLIWRDEAGPAAACA -MVRDLMARQMA-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFART -PRTRQIDVDLAMGEAAHAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Veillonellaceae bacterium TaxID=2049049 RepID=UPI0012B9A6AE ---------------DKAAVSLYCRPLDGGDDF--FYRDRVMPSASLIKVPIMACVFRQEK -EGQLSFDAAYPVYGN--VEGGSFYDLPEGTEVSLRTLVFHMIVESDNTCTNMLIDVL-GF -DAVNEEIRRQGMEHTLLRRKMMDFEAA-RQGKENVTSPGDMGRLFLRLASGTCVDGRRDE -AMRAILAQQED-NCILPAQIPNTVAVEHKTGELD-GIYHDCGLVWKQGR-PYVCCLMADG -IV--------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces cyaneofuscatus TaxID=66883 RepID=UPI0013DA3EBB ----VERTIRSLFDDAGVRGWLHVADLHRPARV-VVDPDAQVPMGSVYKIALMTAFCRLAD -AGLVDPRHRLTLEAADRVPPTGLSILRDPVTMSLRDLVVQMMSVSDNTAAHAVLRTV-GA -EAVDGMCADLGLPHTRIHGGVVGTFDVYDPAYKASSTPAETARLLRAIWTDEAASPESCS -FMRAAMLTQPW-THRLASGFPDDVTIHGKTGTFGS-MRHEAGVVELADGSVYTAVVFTQA -ARADLPRADAVIGAAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A2G6JI54_9BACT ---QLQARLMEAVKDFRGRVGFYVEHLGSGEKA-EFCADDLFPTASMIKVPILVTLFDAIE -AGRVDYEAELQYEASRLYPGNDLLGSFRDGEISIPKLILLMETLSDNTASLWLQELAGTG -TAINAWLAAHGFEKIRMNSRTPGRKPDWERYGWGQCSPREMAGLLRMIREGKAGTAWASY -RMRRALARSFW-DGRALAAIPPEYEVLSKQGAVSD-SRSEVILVHAPGGD--YVACFTTD -DQADDNEGYVLLRKLSRICWQHf ->[subseq from] Serine hydrolase n=5 Tax=Bacteria TaxID=2 RepID=A0A165E8P9_9MICO ------DEINGVWTSLGAQGFLFAEDLETHRSV-GIRESARIPLASVGKVAIVAGLLDAAA -DGVLDLTRRVVVDPTTATPGTGISGLHDPVEMSLRDLAAMALSVSDNAAADTLFALV-GP -ERITALLHRFGIRSFDVVAPMSHLYDQLPDSAFNTGTVRATARLFELIHTGRLLGAEDSA -VLRDLLRRQIF-RHRIAAGFPDAVSYYGKTGTFLN-FRHEAGVIVDSDGTAYSIAIFTRS -TIATQPELDASIGYCARLAIEH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces huasconensis TaxID=1854574 RepID=UPI000FD8AEBA ----------------------------PSARV-AIDPTERLPIGSVYKVPLMAAFCRLAD -AGLIDPCRRVTLEPDERVPPTGVSILSDPVTVSLRDLVVLMMTISDNASADAVLRAV-GP -DAVDALCRDLDMPDTHIHAGVVSNFSVYDPALKASSTAADMARLLRAIWTGEAASDERCA -FMREVMGKQAW-AHRLASGFPDDVAVYGKTGTFGS-LRHEAGVVELADGSAYTAVVFTQA -ARSDLPRADAVIGAAARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. URHA0036 TaxID=1298860 RepID=UPI00040EEA1F ----IGQDIAEIFADAGATGFLHARQIGGGPEV-NTGADEPVVLASVFKILVLTAFVRAVA -AGDLDPTERTTVTARYRVGGVGTAGFADDVEASWRDLALNMMTMSDNAATDVIYHRL-GA -DAVNRVVSDLGLQKTRLIGCCEDLFAAVHPLKTSHSTPREVATLLNALWTDTAAPAEACR -KARDIMALQIW-PHRLTSGFPGEVSLAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -GSL-ADRQPLVDASIGRAAF--- ->[subseq from] Serine hydrolase n=1 Tax=Ferruginibacter sp. BO-59 TaxID=2294116 RepID=A0A3M9NGP3_9BACT --kKLENKLRVLLSSFHGTAGVYVRNLRTGKEA-AIIADTIFPTASIVKVPILVGIFKKID -EGVYTYHQPLIYRDSIARGGSGLMQFFKDSTTEVRTLVSLMLSHSDNTAAVWCEKLAGGG -VEINSWLEKNGFRYTRVNARTPGREKMNKEYGWGQTTPREMSDLMVMIREGKTVSKAASE -QMYRDLTDVFW-DEYALSQIPPYVQAASKQGMVD-ASRSEAVLVNAPHGD-YVFYVATKN -NKETNNEAWQLARDVSSLLWNYf ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329UB22_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGRTV-EMGADEEFETASTIKAYILAVLYLQAS -RGKASLTEEIEYQPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL -DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD -FH--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter sp. NFR10 TaxID=1566292 RepID=A0A1G4TVN1_9SPHI --sKLSAKLNEAIKGFQGQVGIYVHNLKNGKTA-EINADTLFPTASMIKVSIQCGVMDKIE -KGELKYNQKLVYRDSLLYAGEDLLGSFKDKDVQLSKVAMLMITMSDNTASLWLQKLV-GG -EYINNWLNQNDFKIMRVNSRVPGREAIRRIYGWGVSTPREMCRLFAMIREGKAVSPAASE -RMYRNMGRIYW-DEHALSQIPPYVHTISKQGAVDE-SRSETVLVNAPHGD-YVFSIITNH -NKDT------------------- ->[subseq from] Serine hydrolase n=1 Tax=Gordonia terrae TaxID=2055 RepID=A0A2I1R717_9ACTN -------------------------------EY-CHDADTPVVLASVYKLAVLISLCRMAD -RGDIDLSASLTVDPTRWAQGPTGLALFVDPVLSWRDLATSMMTVSDNVAADVILAQI-GL -QQVRDDLVELGLTNTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAPSCE -FVRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVVEFPGELPLAIAVFTMS -ARSELPEVDRAIGLVARAVVT-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000380893C -----------HLDRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARRSSTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG -DHPDRSADTQLLADVSAHA---- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_2_67_6 TaxID=1805068 RepID=A0A1Q7P295_9CHLR ---DLIRQLDGLVASFPGGAGVWVSDPNVPTPLfMHDPDEQVIAASLYKLGVLAEAERRVD -AGQLHYNDQVVIQPEDVTADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG -ANVDVTLQNAGIADFHVALDESE---------DHWATPRAVGMFFTLLARRQLISPAASD -RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA -LD---EDADNFISSVGASVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG07_land_8_20_14_0_80_39_18 TaxID=1974882 RepID=A0A2M6YRP4_9BACT -----KEAILEMIKPLRGKYGIFFQDLESKNSF-EINGEEIFTAASLIKLPVILTLYREAE -AGRINLDEVYKLQNSDKSSGAGSLQKSLGFEITFRQMAELMGKQSDNTAFNIVSRKL-GK -EKIQELIDALGMKNTSFDENE--------------TSPEDIGLFFRKLYGEGIIYEKDKD -EILSFITNTIW-EDRIPAGVPKGVKVSHKIGTEV-GVISDAGIVFAQ--KPFILVIMSQE -AN--EIEAKKALPEITKKIYE-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI00077CA0C6 ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNQAAERQ-AIGALS------- ->[subseq from] serine hydrolase n=1 Tax=Catellatospora vulcania TaxID=1460450 RepID=UPI0012D4596C -----TNRIAGAFAEADMRGWLHARDLDTGREV-AVDAHDQVVIGSIFKILLVLEFARQAA -AGSLDPADRALVRAGDRLGGWGTAGCADDVEMSLRDLAYFTMSVSDNTAADLLLHRV-GP -DLLPLLAQELGLTRTRLVGGPRELLAVFDPAQTNSSTPEEITRLLGLIWRDEAGPAQACA -EVRALMLRQLF-WTRLAAAFPPGVRVGGKTGTLP-GLHMEAGVVEYPDGGRYAVAVFAKT -EHLSMPELDLVLGRAAKLAVD-- ->[subseq from] hypothetical protein n=1 Tax=Kallotenue sp. CFH 73958 TaxID=2592335 RepID=UPI00128C34BA ------DELTALLESAAGDYSLCVWR--DGAQVyGYREHVTRSAASLVKVPLALAIVDA-- ---GIDLDAVVILREPDRVAGDGTFDRAPAGTATVRELIGYALTESDNTASNLLIDRI-GM -DRVNAWLTQHGLA-TRLRRRFMDHES-LRAGRDNTTTAADMCAILE------LLRESRYE -WFIDLLSHSVA-DGKLEAGLPPGVRLAHKVGDLPS-VEHDAGIVFAPGS-PYVIAALAVD -LP-DSQSGRRALAAASRLVWR-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382BZA6_9ZZZZ --aKLQTNLDRIVAAYEGVAGLHVIDLSSDDRL-AVNDDLIFPQASSIKVTILLELFRRAQ -FDPDILRKRIVMNDDVRTGGSGVLRVLTDGGLSLEDYAIYMVVHSDNTATNILIDEL-GM -DAINQLSSRLGAPRTKLQRKMIRPEES-ARGNENISTPVDAATIMAKIASCDLMDRSACV -RVREILEIYKGG--PVREPVPRQIPIAFKPGGIT-GVATVWALVGLPDR-PYVLSVMSNY -GG----NGGALIEAVSAVVYEYf ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Daviesbacteria bacterium RIFCSPHIGHO2_02_FULL_43_12 TaxID=1797776 RepID=A0A1F5KH50_9BACT --kSLDEAVNSSLKGVAGDYSLSIKNLKTGESY-ALNEHKSYQTASLYKLWVMATVFDQIQ -KGALTESQVLSQSADILNSIDSVDAEIKGGQYTVKDALELMITISHNYAALLLSEKV-RL -SQVASFLESNGFNESKVGTDGSV-----P-----ETTAADMALFLEKLYTGKLANTENTD -KMIELLNRQRL-NNKIPKGLPAGVVVAHKTGEIGT-FTHDAGIIFTPKGD-YIEVVLTDS -QQPS--IAEDRIGALSRQVYDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia alni TaxID=33907 RepID=A0A2N0IG08_9PSEU ----------------------------TAREV-GVGAHVPVVMASVYKVFVLVAYCRAVD -AGTVDPREPVVVPVRRTPGITGISALADPVTMSWRDLVTSMVTASDNAAADVVHTRV-GR -DRVAALPAELGLTGTRIRGGTDDVFAALSPVYGSSTTAADTTALLGMLWRGELASDGSTA -FARRVLGAQIW-PHRLRAGFPAAARVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVYTHA -ARSDVPRADAAIGAAARVAVH-- ->[subseq from] serine hydrolase n=1 Tax=Pseudoclostridium thermosuccinogenes TaxID=84032 RepID=UPI000CCC4EB8 ----IKRELENYIEGFEGQYGIHFYSLYDRSEF-GINDTDEYDAASTAKLPLILLIYKKVE -KGYINLDDILTYTKEDYSEGTGVIRYDFGKKYTVRELAKLSIEESDNVATNMLKRLIGGE -KVYREFMKQSGGIVVDYDR--------------NISCPKDMSLYLKMVYDFYKENEELGG -ELMEYLQNTAF-NDRLNKLLPPNVKVAHKVGTQVR-AVHDVGIIYAE--KPYILSVMSKD -VD--EAEAPDVIANISEKVYK-- ->[subseq from] Uncharacterized protein n=1 Tax=Pseudoclostridium thermosuccinogenes TaxID=84032 RepID=A0A2K2FF95_9FIRM ----IKRELENYIEGFEGQYGIHFYSLYDRSEF-GINDTDEYDAASTAKLPLILLIYKKVE -KGYINLDDILTYTKEDYSEGTGVIRYDFGKKYTVRELAKLSIEESDNVATNMLKRLIGGE -KVYREFMKQSGGIVVDYDR--------------NISCPKDMSLYLKMVYDFYKENEELGG -ELMEYLQNTAF-NDRLNKLLPPNVKVAHKVGTQVR-AVHDVGIIYAE--KPYILSVMSKD -VD--EAEAPDVIANISEKVYK-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003822246 ----------AHLDRMPGTVSAYLASLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AGRLAPDTAVPVRNEFDSAQPGAAWDQLGGTAPLCWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSSTGRGIEDLAAR-AAGITNLVTTADLAALLRGLARGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG -DHPDHRPDEDACQLIADISAR-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aurantiacus TaxID=254410 RepID=UPI00040FA93E ---DLKREIMLLCESLTGDVSLHIRI--GDEEI-GYQSNVPLIAASLIKVPCAYALLMLSQ -EGDVDLDELIVVTDREKIGGTGVLVHMPGDVLTYRQLVSLMITVSDNTATNVIIDQV-GI -PYIQEVVDRSGCEGTKIQRKIMHTNPN-EQPLKNVMSAKDMNRFLMLIDQGTELEEGNKA -FLLSCLTGQQLIHKLFSDGLPPTAFVAHKTGDDIK-MEHNGGIIKINNKT-AYVTVMTDQ -LERN-IDGQALIQQVGKQVYDY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL S-384 TaxID=1463905 RepID=UPI0004C723E8 ------DGIPEIFERAGCEGALCVRPLEGDAEV-GLRADEPVVPASVFKVQVALEVETAFA -EGRLDPRERVTLGAADRTPGPVGLSLFEDDALSWRDLAVLMLTISDNPSTDALLRRV-GV -DALNATAARLGLTGTVVESDLRTMLDALDPSRGTRTTPRDMAELLRLIWTDRAGPAAACG -RVRDVMARQLT-RHRIAGGFRPPVRVAAKSGSLLGVVRNEIGVVSYPDGRRYAAAVFTRS -RPADDVAISRAIGAATAH----- ->[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A2H1MMI5_LACSK ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] Uncharacterized protein n=1 Tax=Mucilaginibacter gotjawali TaxID=1550579 RepID=A0A0X8X5H8_9SPHI --tKLNAMLQDAVKGFNGQVGIYVHNLKSGKTA-ALNADTLFPTASMIKVSIQCGLMDKIE -KGLINYNQKLVYRDSLLYKGEDILGSFKDGDIEVSKVALLMITMSDNTASLWLQKLV-GT -DYINNWLDVNGFKVMRDNSRATGRDAMHARYGWGVTTPFEMCRLFTMIANEEAVSPAASE -RMIRNMGRIFW-DNTALSQIPPYIHTISKQGALDD-YRSETVLVNGPHGD-YVFSIITNH -NKTQDNEADELIRKVSALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. col6 TaxID=2478958 RepID=UPI0011CD388F -------ALRAAFTDAGVTGRMHALDIESGAEL-DVCGDEVVCTASIHKLPLLVTLHERAA -AGDLDLTEQIDCPPLGRSAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL -AAVNRTAADLGLTRTVATHSFGAMMAALDPAWANRSTPRELTRLLASIWRDTACTPENGA -AIRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEVGVVEYPDGGRYAVAVFTRT -LSAIVPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Edaphobacter modestus TaxID=388466 RepID=A0A4Q7YTA5_9BACT ---VLQQKIEAIAATHKGHVTLYATQLNTGKTV-ALDADRQVQTASVIKLTILFEAMEQVR -DGKAHWEEKLTLDKANAVTGSGVLTFFDTSLITLKDVLTMMVIVSDNTATNLAIDRF-GA -SAVNARIAWLGLKDTHLYKKIGKPATDQPQFGLGKTTAHEMEMVMERIGRCQLAGPGEEA -QPGDTMLRNQFYRNTIPRYLESGSGIASKTGSLN-AVRNDVAIVVGKSG-PMVVSIFTYG -NDTADNEAEMMIARLAKEIVESw ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=A0A6B9E939_LACPN -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMVRRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDEAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Beta-lactamase n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A346QWK4_9BACT ---ETREQIERAIADTKGKISVLWQEIGAAMPMfAYNDSRRVSAASTIKVAIMAALLEDIR -AGKRTPGDLLFVPQAGILDDTEVFDT-GERDASLFELMTWMIVSSDNTATNVLIEAA-GM -DAVNAYCAGIGLKDTVLGRRMLDFDAR-GRGLDNHTSARDQYILYNKLCRGEILDERLCA -DALGILRKQRS-GDILRRYIWEDVAVAHKTGGLDH-LCHDAGVFFLPQKTV--------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A164L040_9NOCA ---------RQIFEQAGVQGWLHARCLDCGAEI-GDGADEPVVLSSVVKVLLVLELGRQIA -AGQVDPTDRVRATAAYRLGGPGTSGCRDDVEYSLRDAAYLALSLSDNTAADLLFERV-GL -DNVRSLARELGLTRTRIAGALRDLLLALDPRRTTASTPREMTRLLDLIARDAAGPPATCA -WLRELMSLQLN-QHRLAAAFPSNALVWGKTGTLP-GLRNEIGVVEFPDGARYAVAVFTKA -RVHRLPQADRAIGTAARTAIE-- ->[subseq from] Uncharacterized protein n=3 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F7X8L4_9BACT --qKVTSDFKKNTNNLSGVYGLLVIDLKSGYSF-GLSQGESFTAASLIKLPVMAAAFRESE -KGNLNLATIYTLKDADKIAGSGSLYYKPAGTLSYRELLMLMGKQSDNTAFGIMRKVL-GD -AKINEVIKTIGMNSTSLE--------------DNSTSPDDIGTFFKKLWEGKVTSKDSAD -EILNNLTETSF-ENWIVAGIPANVRVAHKYGRELH-VVNDAGIIYADN--PFVLVILTKG -VV--EKEADGIFSSLAGLVYD-- ->[subseq from] serine hydrolase n=1 Tax=Terrilactibacillus laevilacticus TaxID=1380157 RepID=UPI0011468887 ------EKLDRLVSPFGNKVSVVIKE--GKNHY-SFNESTKMLSASLIKLPIFLYAFDQVK -KGTLSLDQKIPVSPEKMVDGSGIIQVIQDVRWSIRDLLGLMINVSDNTATNVLMDVL-GI -EQIQSWIENHGLNGTSIQRKMMDMQAK-KEGKENFTCASDVSHCMELIFLRPNSLSCEFP -FVKHYFLNQQF-RGKIPGKIETPVKIYNKTGEME-GISHDTAFMKLKDKT-SIVTCMTSG -FE-DATEADQLIQKMGEWVY--- ->[subseq from] Serine hydrolase n=1 Tax=Gordonia rubripertincta TaxID=36822 RepID=A0A554UPL9_GORRU ----VDRDVAGILADAGCSGWIHATTIGSPQIEySYDADAPVVLASVYKLAVLISLCRSAD -RGDVDLASSITVDPTQWAQPTGLAAFRDPVTLSRRDLATSMMTVSDNVAADVILDEI-GL -DRVADDLTSLGAASTRIVGGVAELHGAYDAAYSSSSTPRDCTTLLSAVWADRAASAEMCE -FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEIGVVEFPGELPVAVAVFTMS -ARSELPQVDRAIGEVARTVVT-- ->[subseq from] Serine hydrolase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=A0A1T3P732_9ACTN ----VRGRITAAFADAGVNGSLHALDIDTGREV-EVGADTLYSTASLHKLCLVTTLFREAE -AGRVELTRRLELPAGDGRSGTGVAAMLDPVTMSLRDLASLTVAVSDNAAADALWDEL-GL -DTVNATMVKLGLTRTVAIEPLRELYAALDPNRSNRGTPRDLTRLLAAIWRDEACGGEYGA -GLRRVLGLQAW-SHRLASGFPDDVRVSGKTGTLPT-MRHEAGVVEYPDGGRYAITVCTHS -ADAALPAADAVIGTVGRLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinopolymorpha singaporensis TaxID=117157 RepID=UPI000B83BE71 ----------------------HAVDLHEDREI-GHHSREQVALASVFKLPLLVAYARMVD -AGEIEPEATVILEPSRRTPGSTGFAAMADAVVSWRDLARSMIAVSDNAAADELLDAV-GL -HRVRSLLDDLGLHQTRITGGTRDLFDD-PADPGTVGTCQDMTSLLAAIWADRAASPGQCA -YIRTVLAQQIW-TQRLAAAFPDDVVVAGKTGTFI-ALRHEVGVVEYPNGEAYAVAVFTRS -PRNRLPAADAAIARAAKIAVA-- ->[subseq from] Serine hydrolase n=2 Tax=Thermoanaerobacterales TaxID=68295 RepID=A0A3G2R2E7_9FIRM --eSLKLELQNYIKDRPGKISVYVKDLNSGKTL-ELGSDNVYAAASTIKLPLVLYLYELAA -EGKIDLNATLTYTQEYYTRGTGILQGEPFGGYTLRELSRLSIEYSDNVAWKMLLDFI-DH -DGLTAFEKSLGASATG---KIDGL---------YITTPRDMGRYLEELLAFSKKYPDYGN -ELLYFMEHSIF-KEGIPQDLPDGTLVAHKMGALDD-KFHDVGIVFG--KRPYIITIFTRD -GW--EAVSLQTLADISRMVYD-- ->[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Lactobacillus sakei subsp. sakei (strain 23K) TaxID=314315 RepID=Q38UX1_LACSS ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI0006903BDA ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI00040071E1 ---DIRERIEAVFAAAGAEGSLHAREVGDGAEV-SVGADDQVVLASVFKIPIALAYAREVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRL-GQ -ETICRVVADLGLIRTRLIGSCEDSFRMCDPERETSSTPRETTALLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSGFPSGVRIAAKTGTLP-GIRNEAGVLTLPGGRRFAVAVFTRA -HSLDLPEVDASIGAAARLAVDH- ->[subseq from] Serine hydrolase [Lactobacillus sakei] n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A508UZR1_LACSK ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha singaporensis TaxID=117157 RepID=A0A1H1R5Y1_9ACTN ----------------------HAVDLHEDREI-GHHSREQVALASVFKLPLLVAYARMVD -AGEIEPEATVILEPSRRTPGSTGFAAMADAVVSWRDLARSMIAVSDNAAADELLDAV-GL -HRVRSLLDDLGLHQTRITGGTRDLFDD-PADPGTVGTCQDMTSLLAAIWADRAASPGQCA -YIRTVLAQQIW-TQRLAAAFPDDVVVAGKTGTFI-ALRHEVGVVEYPNGEAYAVAVFTRS -PRNRLPAADAAIARAAKIAVA-- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus sp. HMF7620 TaxID=2682977 RepID=UPI0012F7B4E9 -----------TEAGFKGEVGLRVCTLDGTELA-AWQAGLVFPAASTIKVPLLILALQEAQ -AGRLDLAARVTLRAADQVPGAGVLHELAPGLLTWQDVLTLMTVVSDNTATNLVIERL-GL -EWVGAQLPLLGFPGTRLVGKLQVPPEAQQRGERNVTTAHDQTEGLRALVAGERLDAAHTA -LALDILGRQQL-LDILGRRVPDGYRVASKSGELN-GVHHDVGVLFTP--RPLLVALLSQG -GTREHPENRDVVA---------- ->[subseq from] Serine hydrolase n=2 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A6B8G4I3_LACSK ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0007C1212E -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRSQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLILNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKTGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium tepidiprofundi DSM 19306 TaxID=1121338 RepID=A0A151B4C7_9CLOT ------KELKRYLDSRKGNFSFYFEDLKDGYVY-GFNDLVKMPCAGCIKLPVAMALFKEIE -NNKFSLDTNIRIGKDDIEEASGIIHEFKEKDYTLLELLIAMLIQSDNTAANKIIDLI-TK -ERINEIFLDMGLNDTKLVRKTSDRLST-DDEGENYSTSFELSKCYKILYEGSYLNKEHSE -RLLKILRRQQR-RNKIPFYIPKKCSIANKAGRLD-GIEADSALLTVSKGD-FIFTAMSCN -LP-NNVYGITTIARISKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00035C2B25 -----------HLDRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AERLASDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARRSSTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG -DHPDRSADTQLLADVSAHA---- ->[subseq from] serine hydrolase n=1 Tax=unknown TaxID=N/A RepID=UPI00143EAFE4 ----------------------------RVCEV-AVGADEPVVLASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNSAADLLLDRV-GL -DTVRLLAKELGLDRTRVVGGPRDVLEVLDPLRTNSGTPRETTELLRLIWRDEAGPPEVCA -QVRDLMSRQLF-RHRLVSGFPGGTVIAAKTGTLP-GLHTEAGVVRYPDGGCYAVSVFART -HEATGPEVDAAIGAAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Paenibacillus sp. 7124 TaxID=1850370 RepID=UPI0013ECAC44 ----SNAAIEALVEKFSGNISVRFKDIHNQTDY-CLESGTVRPTASTIKLYILGAMMEQAQ -QGMCKLSDRITVKSEVQVGGSGVLKDLLPGILTICDIATLMIVFSDNTATNMMIDLIGGI -EAVNKHIKNQGLQNSELRNRINFMEIGDDIRRLGVSTADDFIIYLEKLACGYIFDEDYTR -ATLNILSKQHY-LDLFPRYLDQGVKIMNKTGFFP-GVRCDVGLIELVGK-HYAYAVLSDN -CAHMENEASMLIGKIGRILYD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora globbae TaxID=1894969 RepID=A0A420EY55_9ACTN -----------------------VVDIDEGRAV-AVRADEQVVIASIFKILLVLEFARQVV -EGQLDPAERVLVTADDRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLARTRIVGGPRQLVEVFDPQRTTSGTARDITRLLALIWRDEAGPAQACA -MVREWMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART -EQTRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis circi TaxID=871959 RepID=UPI000E26BB2C ------ETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA -EGTLDLGTRIAVKPGHPTPPYGLATFRHEVLMSWHDLAILMIGISDNVATDLILAEV-GK -DAVNSTLRRLGFTQTVVPQDCGELLAALQPEKSCSTTAAEMTRLLGLIWRDEAAAPQACA -DVRHWMELQVW-PHRLRSGFPDRIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -EDSRVPERDAFIGFAAATAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID3343 TaxID=2690260 RepID=UPI001370DD01 ---AVEDRLRAVFEAAGTEGFLYVRDVDDDDEF-TFQGDSRVVLASVFKIQIALEYARQVA -AGKLDRASRHVLGDAFKEGTGIGTDSFAYDVLSVRDAAQLMMTMSDNAATDLVLGIV-GR -ENVRATLDELGFQSTGVTGCRELFDQVRDPGHAATSTPREMANLLTAIWRDEAGPAEACA -EVRDLMGRQIW-PHRLSSAFEDEIRISAKTGTLW-GVRNEAGVVEYPDGKRYAVAVFLRP -ESFRLPAVDAAIGRAAREVIDH- ->[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium SM23_28_1 TaxID=1703395 RepID=A0A0S8CBN5_9CHLR ------------------SYGVVVKNLVSGAVA-EVNPHKVFETASLFKLWVMYEVYKQVE -LGLVDMDEELLVTPYYASFDAGSLPVEVCDTLTVREALWAMVTYSDNASGFLLCDKV-GM -GNIHRDLQALGLTESAFRPE------------DVTSTAADMALFLEMLALGADVSREANR -EMLDLMLAQKV-RDRLPALLPPGTEVANKTGNLDE-ATHDVGIVYDPQP-TYIIAVLSDR -GAES-----EPIALLSRAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Serinicoccus chungangensis TaxID=767452 RepID=UPI0013053384 -----EEQIADLLRDAGARGWVHAIPVAGRHEV-SHRADEPVPMASLYKVLLAVAWARLVD -AGDLDPRAPQVVAASDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLHLV-GL -DRLRAVAADAGLEATTVHGGTGHHQRVYDPALSSTTTARDMTRLLTKLWRDELTTPERGA -WLRRAMARQAF-RHRLASGFPDDVEVASRTGSLL-ALRHEAGVVSFPGEEPIAVAVLTHA -LNQHLPDVDRVIGTIGRVAV--- ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F7Y010_9BACT ------ESFKEKTESLSGVYGLYVIDLESGFSY-GVNESETFQAASLIKLPVIAAMYLEAE -EGTLDLDSKYRLKNSDKVSGAGTLSGKPAGYITFANLINLMGKQSDNTAFAISMNLL-GD -AKINDVIKAIGMANTSLDENE--------------TTPKDIGIFFEELWYGNIVSQENRD -KILDSLTETSF-EEWLVAGIPGGTRLAHKYGREVH-VVNDAGVVFAESRRPFVVVIMSKG -VIE--NEADEIFPELARIVYD-- ->[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces sp. FR-008 TaxID=206662 RepID=A0A0S1UGV3_9ACTN -----------------------------------LGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTRGDRLGGWGTAGCADDIELSLRDLAFFAMTVSDNSAADLLLARI-GL -DTVRLLAGELGLDRTRIVGGPRDVLEALDPLRTNASTPREITRLLRLVWQDEAGPPQACS -QVRELMARQAF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVIRYPDGGLYAVAVFARS -REASRTEVDAAIGATARIAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A147DZ60_9MICO ------------------------IGVEGGPEV-TVGADEPVVLASVFKILVLTAFVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEMSWRDLALNMMTMSDNAATDVIYHRL-GA -EAIDRVISELALRQTQLVGCCEDLFAAVQPLRTSHSTPREVTAVLNALWTDAAAAPEACR -QARDIMALQIW-PHRLTSGFPAEVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -ASLS-DRQPLVDASIGRAAF--- ->[subseq from] serine hydrolase n=1 Tax=Hungateiclostridium cellulolyticum TaxID=35830 RepID=UPI0001E2FB13 --dKLKSDLGQYISKFAGQYGIHYIDLENNYEF-GINDTNEYIAASTVKVPLNYFVYKKIA -AGEVDPKKTLTYTEGDFEGGTGILQNLAGKSFTIKYLMELSITHSDNIATNMLLRHF-GR -KNLKNYMRSLGGTVV--------------KDNKNVSCPKDMAIYMKDVYEFCNSNGELGE -EFKHNLCNTVF-NDRLPKLLPKEVKVAHKVGNQIE-AVHDVGIIYTD--KPYVLTVMSKG -IV-SEEEACNVIAEISKKVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Fretibacterium sp. OH1220_COT-178 TaxID=2491047 RepID=A0A3P1Y5T7_9BACT -----TEELERTCLDFPAVASVFVLEPAGGETF-GHRADERLPSASLIKLFVLWHLFERAD -SGDLDLLEETTLSPGAVAEGGVLHRASPGARLRLEDLALLMLSVSDNTATNALIDRL-GI -DAVNASIRRLGCIKTVLGRKMLDFEAR-RRGLDNYTCAREVGELLARIAQRG-------G -RMLDLLSVQKN-VGKLPAEIPLEPLLAHKTGELP-GHEHDAGILFHRSDRPVIVAALTAG -LP-DRLSGCRLCARVGGIVYERf ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. 602-1 TaxID=2492472 RepID=A0A426GM96_9CAUL --kNLQKRIEAIAARAPAVLGVAVEDLGTRQLW-AFNGDRPFPLGSAARIPILASVMAETE -SGRLPPGEILSVRDVDLSPPSAVADAWPGRQWSVAELETLA-REGDNTALDLLTRRVGGP -GGVNGWLDVKRLEHVSVDRYRRQIATARATDPRDTATPVGLVRLLEAFINRELLFKPDPA -RLLG---R---DPGYLADALPDGASIIQSAGAPRSDTNHAVAFVELKDGRRIAFVVFLTA -STADAAQREAIITDVGRAVLKEf ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535IM28_9CHLR ---DLEHNLERIANGVAAQWGIYVKFLADGAEV-CIKADTPMDTMSVIKIPVLVELFRQVD -----------ALQTEHKRFGTGVLSTLDDGSLTLRDAAMLMIIQSDNSATDLCFDAVGGP -EVVNACMRSLGLTQIQATGTCFNWFRFDGKHPFGLSSARAMGRLLEMIYRAECASDQSCA -EMLRILRLQQF-RTRIPKYLF-GTTTPHKTGDFGPFIANDVGFVEPYQRTPVIVCFFNRH -HRGIWANLEDAVARMSEKVWEY- ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. BMG111209 TaxID=1160137 RepID=UPI00039DF52A ----------------GVHGRLHARCLGTGAEI-DWGADDPVVLASIVKVPLVLEFGRQAA -AGQLDPADRVRAVAATRLGGTGLAGCADDVELSLRDAAYLALSVSDNTAADLLFDRV-GV -DNVRSLLRELGLHRTRIVGAPRDLVHALDPLRTSASTPREMTRLLAAIAHDEAGPPEVCR -WLRGLMSLQVN-WYRLAAAFPPAVAVWGKTGTLP-GLRHEIGVVEYPDGGRYAVAVFTRA -ETQRLPHVDRAIGAAAY------ ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis regifaucium TaxID=546365 RepID=A0A154MVK2_9PSEU ---DIRERIEAVFAAAGAEGSLHAREVGDGAEV-SVGADDQVVLASVFKIPIALAYAKEVV -AGRLDETEYTKVTARYRIGGIGTAGCADDVEMTWRDLAWFMLTMSDNAATDLIWNRI-GQ -ETICRAVADLGLSRTRLIGSCEDSFRMCDPERETSSTPRETTELLDAIWTDRAGEPEACE -RVRTIMAQQIW-PHRLSSAFPSGVRIAAKTGTLP-GIRNEAGVVTLPEGRRFAVAVFTRA -HSLDLPEVDTSIGAAARLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5FMB8_9ACTN ----------DHARELGADIWLHARDLETGRSV-GVGENTSVVTASVLKVPVALELARRSV -AGEIDLTERITVPPGGVPSPYGLSVQRDDTVISYRDLAHLMIVISDNVATDLVIDRV-GK -DRVAALLAELGLTATAVPQNCAEILAALVPERTCRTTPEEITRLLAGIWRDEAAPPEACA -LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEYADGGRYAVGVFTRA -EDPNAPYLDALLGWAA------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus plantarum TaxID=1590 RepID=UPI0003D3D81C -----TDLVAQATNGLAGQTSVAVMPLTGSQTV--VLNNRAQRAGSLITLFIMVTAFDQVH -QNNWRMQDRYTLRAADKVGGTGTLHTLPAGSLTYAEITKRMITESDNTAANIMLDRVGGF -SAVNTEIAQLGLTDTKMARRLMDTA-ALKAGHDNDTSVRDVATVLKRLANLRLISNKADH -AMLTILKANTD-HSKLVKNLPTRATIYNKNGDYQYGVQNDAAIVQNRQGT-FIMTMMTAS -GERT--AQTVAMNDLGQALYR-- ->[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A2K4QEQ3_LACSK ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] Peptidoglycan-binding domain 1 protein n=2 Tax=Thermoanaerobacterium xylanolyticum TaxID=29329 RepID=F6BH17_THEXL --qELKDNIETLLSQHTGNYGVYFIDLNSGETF-DINGYDSFIAASTYKVPLNFYVYTLIT -EGKLDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY -DNYLNFIESLGAYVIPY--------------SDNVTSPRDLSIYMEDILNYANAHSSTAG -ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYTQK-PYILTIMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Kurthia sibirica TaxID=202750 RepID=A0A2U3ALD3_9BACL ---SLYERLNPIIQSFNGHIAVVIADHDNSRVL---NGEEQTIAASVIKVPIMLYALHEAQ -HGRLDLHKKIAITS--TVGGSGVLSALTSPPQSILNLIELMIIVSDNTASNLLLKEL-GI -QPINAFCEKLHLKQTVIERYFMDEEA-QLKGKNNYVSANDLHKLLLLIGENEVLTNDSRQ -LALNIMKNQQF-TDRLGALNDDTITIASKSGTLDL-IEHDTAIFLVGHY-RLYVTVLTSQ -LV-EVHHGTKLMADMSTII---- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000481FFDB -------------DRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG -DHPDRSADTQLLADVSAHA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella jejuensis TaxID=236068 RepID=A0A542EWG4_9ACTN -----NARIRAVFDDAGVRGWLHAVALDDPDATvELDADGIVPLASVYKLPLLAGFCRLVD -LGELDPRRQLTIDPSDKTAGPTGLSVFADPVASLRDLALSMMTVSDNASADALLELV-GL -RRLAAMLTEFGLHRTWVRRGTAGNLRVYEAANASASTARDLTLLLRRLWAGELLSPEQTE -FVKATMHRQVF-LHRLASGFPDEVRVAGKTGTFG-ALRHEVGVVTLPDGAAFAIAVFTLA -ARGDQPRVDAAIGEAARRAVD-- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Entotheonella palauensis TaxID=93172 RepID=UPI000B7C651D ---TIEQDLNKLCDEQPFHTGWYFKNLRTGDIL-QRHGDVVVPSASTRKIAIMMTALKAVN -EGKLALDQPVVMEAKYQNNDSGCFQHLSSDFIQLRDALIMMIIVSDNTCTGAVADRV-GL -EAINALCQGIGMSGTTHRYGIPGMAGYLPAEKTNATTPADVGLLLEVILQGSGCTPELCQ -LAIDILSWQRL-RNRLPSRLPRKVKVAHKTGTTAN-NYNDAGIVYLGDEPAFILSAYTDG -VPDELPNG--------------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFOXYB1_FULL_38_16 TaxID=1802538 RepID=A0A1F8CUI2_9BACT ---EIISKIQAITSALSGVYGIYVVDLNGENSY-SINENHTFQAASLVKLPVMAGSLYESD -KRTLNLKTKHTLNETDKIAGSGSLYYQPAGSVTYQKLIEMMGKESDNTAFGIMSDVL-GS -EKIETHIKRLGMTNTSIDK--------------NKTTPKDIASFFKHITKDNYLSQTSAD -LLLSYLTDTIY-ENFLPASLPDDIKVAHKFGRELH-VINDAGVVYATN--PYIVVILSEG -VMES--EAEIAIPKISELIYQ-- ->[subseq from] HTH lysR-type domain-containing protein n=1 Tax=Propionibacteriaceae bacterium NML 030167 TaxID=2016500 RepID=A0A255G8N7_9ACTN -----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD -AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA -DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA -AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL -QQETPHHRDWAISETARLAVN-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus hwajinpoensis TaxID=208199 RepID=UPI00136FA119 ----VKEKILECFHGLEGNQSIYVST--TDGEI-ALHADQPVSSASIIKIAILVEALRQVD -DEKLTIDQAVQIDNVNYVGGAGVINHLSRDHWKLADLLKLMIISSDNTATNQLIDLI-GE -HNINHTMKAAGAFHSKLMRRMMDRNA-LKSGLDNMVSGKDTYLLLREFVTQHLLSQSSME -WGVEVLLQQQF-KDKFPSKISKENLLAHKTGELI-GVEHDAGILFTSNG-PVVYAFLTAG -LL-ENRYGREAIANAGRLLYDFy ->[subseq from] Serine hydrolase n=1 Tax=Jiangella asiatica TaxID=2530372 RepID=A0A4R5DIS6_9ACTN ----VMKEIAAVLGRAGTSAALHARPVDGPGEV-ALNADSVSVAASTYKISVLLELACQAA -EGTLSLTSRLRVPADRRSLPTGISAMLDDVELSLRDLALLMMQISDNTATDVVQELV-GT -DRIAARLAALGLTGTSFPHDCARLVGSIAGTTGNITTPRDMTTLVSAIWRDEAGPAQACE -EVRRVMLQQYA-PHRLSTAYRDGPVIAGKTGTFHGGIRNEVGVVDFGGGERYAVAVYLRQ -HEYDDGRADAAIGEVARLAIDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Faecalibacterium sp. CAG:82 TaxID=1262898 RepID=R6QDA0_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS -RGKASLTEEIEYRPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL -DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD -FH--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Firmicutes bacterium ADurb.Bin248 TaxID=1852886 RepID=A0A1V5U194_9FIRM --------------PMGGTVGFYFKDLETGETF-THNEDAPLLAASVIKLPVMAEAFRRME -AGQVLADERFAVRSKDILPGCGALNFHEGIEVTFLDLVKLMICLSDNTATNLVIRRL-GM -DAINENHGRLGLSGTRLNRLLFDAEAS-ARGLENTVSAAGMGKLLELIYRGELVSKQASA -AMLDILLDQRLGRA---------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Clostridium puniceum TaxID=29367 RepID=A0A1S8T992_9CLOT -------EIKRYLESRIGTYAFFFEDLESGFSF-GYNENVQMTSAGCMKLPIAVSVIKHVE -NEKGSFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI -DTINEDLEAQGLKNTKLNRKTSD-ERAVSSGIENITSALDLSKVWKHLYNSSFLNEKNST -MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAN-VENDTALIHLPKG-SFSFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC 05977 TaxID=2203208 RepID=A0A429BLV2_9ACTN ----VIEKITERAKEAGVRIRLHAAEIDGTRRI-GVDEHAPVVTASVFKVPIALELAKQGA -EGGLDLGERVTVQPGHPTPPYGLATFRHEISMSWYDLAILMIGISDNVATDLILDRV-GK -EATEKTLRGLGFEHTTVAQDCGEVLRALQPEHTCATTAEEITRLLGMIWRDEAASPSACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGVFTDA -VDSRVPERDAFIGFAAARA---- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI000A39EE45 ----------AFFEAVGVRGFLHARRLGSSESL-GCDADSPVVLASVVKVPLVYEFARQVA -AGLLDPADRVRASAADRLGGTGSAGFADDVSYSLRDAALLALSVSDNTAADLLFDRV-GV -DNVRSLLAELGLTRTSVIGAPRDVLRALDPLRTSATTPREMTTLLAAIWADDAGA----- -PVREWMAAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGAAYALAVFTAG -GAETRPDIDRAIGDAARAAVDQ- ->[subseq from] Serine hydrolase n=1 Tax=Arthrobacter sp. 9V TaxID=2653132 RepID=A0A653R7B3_9MICC --------------------------IGDGPEV-SLNADEPVVLASVFKVPFAVAYSREVS -AGRLVETERTTVTSRYRVGGLGTAGCADDVEMSWRDLAFFMLAMSDNAATDVLYHRL-GQ -AAVDAVLDDLNLKHTQIIGCGEDLDHILDPARTPSSTARDIVRLLEAIWTDSAGSPEACE -RVRLMMAQQI-WRQRLASGFDGSVLVAGKTGTLP-AIRNEVGVVTYPDGRHYAVAVFTRA -ATDPQPAIDASIGQAARLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=A0A498AXD4_9ACTN ------------------------------REV-AVRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRHLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA -MVRGWMARQIF-WTRLAAGFPPGVRVAGKTGSLP-GLHLEAGVAEYPDGGRYAIAVFVRA -TQTRRIDVDLAMGQAARAAV--- ->[subseq from] serine hydrolase n=1 Tax=Bacillus gottheilii TaxID=859144 RepID=UPI001117E1FC ---QFNRDVQRLTSAAHGRVSLFIES--DKGVI-EIDHHALYRAASTIKIPILIEALRQAE -SGRLDLKQPISISSAHITGGAGILQSSLPAEMKLVDLLSLMIVVSDNSATNILIDLL-GQ -NQIVQCLKVMNLQETKLQRKMMDIEAG-RRGFENTTSAYDLGICLKFLIEDGLLKEESRA -LALEMMGRQQF-RKLAYSVNGSKITVYGKTGELP-GVSHDCVIVKKDHH--LLYAVVLMD -GFTQAEEALIYFSRLGR------ ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CA-126428 TaxID=2073158 RepID=UPI001304F551 ----------------------HAREIGGGPEV-AVGADDPVVLASVFKIPVAVAYAREVA -AGRLDETARTRVGSRYRIGGIGTAGCADDVEMSWRDLALFMLTMSDNAATDVVYHRI-GP -PAVDRVLADLGLHRTRLIGCCEDLFAVLDPARTTSSTPREISELLDAVWTDRAGEPAACE -RVRSMMARQIW-PHRLSSGFGSDVAIAAKTGTLP-AVRNEAGVVSFPDGRSFAVAVFTRA -NSERQPAIDAAIGRAGRLAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Jiangella aurantiaca TaxID=2530373 RepID=A0A4R5ADD5_9ACTN -------ELREAFAAAGVAGLLHAADLGDGAEV-GVDPDAAVVTASVFKIPVLVELCRQFA -TGERAPTDRLRVPAGSRTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -ERINAGMAALGLSGTVLEEDCAGLFRVLNPEKTNRSTPRETTTLLRRIWTADGLPEQACA -EIRRIMGLQVW-PHRLTSGFPDDVRVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL -PGRENPAADRVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter insuavis TaxID=1287735 RepID=UPI000B01EDC0 --qHVEAALVPLLAATPARVSLSLRDLDGGIVL-ARQADRQQPSASIIKIPILLALLEAVA -GDRYALEQPLVLPAGDRAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIELL-GF -DEINQWSQRAGLTASHLQRRMMDAAA-REAGRDNFTSADDATAALCWLLRDGALPAPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVVLAVLADG -FTLQGGEGAALLGQIARA----- ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382RA93_9ZZZZ --dKLETAILGLIQGFNGDVGVYVRHLSSNTAV-GVNENKIFPTASMVKVPILVKIFDKIE -AGALTMDSVVIFNKALINYGDDALARFKDGEITISKLLTHMITFSDNHASLWLQDMAGSG -TAVNTWLEKNAFAHTRVNSRTVGREAEYEEFGWGQTTPREMAELLVMIRDGRAVSPSASA -DIYRHLTRIYW-DDEALSQIPPTVQAASKQGEVSQ-SRSEVVLVNAPSGD-YVFCIITNN -QATQDNEGFILIRSLSKLLWQHf ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis niigatensis TaxID=369932 RepID=A0A2N3WK39_9PSEU ----ASETIARRAEEVGVEVRLHAAEVDGTRSL-GIGEDVPVVPASVFKVPIALELARQAA -EGKLDLGTRVAVRPGHPTPPYGLATFRHEVLMSWHDLAILMMGISDNVATDLILAEV-GK -DAVNDTLRRLGFMQTIVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA -DVRRWMELQVW-PHRLRSGFPDSIRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -EDSRVPERDAFIGFAAATAVE-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus sp. WWJCD1 TaxID=2022519 RepID=UPI000B9C274A ---TTDEQLRAVFADAGCRGWVRAERIDTGTTV-DYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL -DSLATVIEDLGLEQTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASPTQCL -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPDETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Leucobacter celer TaxID=668625 RepID=UPI0006A7D02B -----KSRIEAILSEAGGTWHVSAR-LGGQTVY-SLNEEEAVRSASTIKLTVLLAALRAVM -SGRLLLDQQVQLP-DECVGGSGVLRLLPSVRLPLRELLVLMIAVSDNTATNAVIDLV-GF -DEINEISGAAGAEGMILARHMMDTAAV-LAGRDNLVTARGLTAIVEALIMPDILPGELAT -VAREMLGAQQF-NERIPGLLPGSLTVLHKTGELD-GICHDAGAVVLPDGRFLLISVLGVG -VGANRHTPGDTIARITREIV--- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. Root1433D1 TaxID=1736463 RepID=A0A0Q7RQT4_9MICO ---------AEIFADAGATGFLHAREIGDGPEV-TFGADEPVVLASVFKILVLTAFVRAVA -AGELDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDIIYHRL-GG -EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTAAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA -ASLV-DRQPLVDASIGRAA---- ->[subseq from] Serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A2L0E640_LACSK ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDDA-ARSQGLDNYTSVKDVLQFLNQLYQNR--DQAPYN -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKAND-PFAIVVLTNQ -VQNPTAERQ-AIGAL-------- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Nocardia brasiliensis TaxID=37326 RepID=A0A379A282_9NOCA ----------EIFRKAGVRGWVHARCFGCAGEN-GLEADEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRVRAADRLGGVGTAGCFDDVELSLRDAAFFALTLSDNTAADLLFDRV-GL -DNVRSLVRELGLIETRIVGAPRDIVQALDPRRTTASTPREMTRLLALIGQDLAGPAQACR -WVRDVMREQVN-WYRLAAAFPPEAQIWAKTGTLP-GVRNEIGVIEYPGGSRYAVAVFTRT -ESQRLPEVDRAIGAAAMAAID-- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora endophytica TaxID=1642495 RepID=UPI00101BB4A4 ----LRRALESAATSTDGVWGFAVRE--RGETVvSVNGDVAMRAASTIKVPLLILALQDVA -AGHRELSDVLVV-PGERVGGAGVLRLMPSVRLRLDETLELMIGVSDNNAANMVIDML-GV -DDAAARITALGARSTHLGRRLYDVE-AMRAGLDNVTTADDQALLLGLLGSTGLLPDDLRT -IALDILGRQQF-NDRIPAALGPDIVCRHKTGELA-GVRHDVGILEFDGRS-VVFTALGSG -LTDPTGVAGAVIATAARAVVD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium polynesiense TaxID=1325933 RepID=UPI000590EDC4 -------EIKKYFESRIGNYSFYFEDLNSGYVY-GYNENNKMTAAGCMKLPIAMVLLKEIE -NMKYKLDDKIFISEEDKVYGTGIIHEFLPREYTLDELMKAMLIQSDNTASNKIINII-GK -DRINEVIKEMGLSNTVLNRRTSDEIYD-DNNDENITTSYDLCKCWKMLYRESFLSKELSS -KLLRVLGRQQLKSKSSLYILNLKINIANKTGDKQ-GVENDTVLITMPKGT-FSFTVMSSK -IPNS-VYGIVTIAKAGKMMFD-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI0004933CAE ---ETSAQIAEIFAGAGATGFLHAREIGDGPEV-TVGADDPVVLASVFKILVLTAYVRAVA -AGELDPAARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT -EAMDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus ndiopensis TaxID=2004408 RepID=UPI000C077E60 --nQLESTIHSLVNKVMDHFSIFIRTADGNIT---INAHEPRKAASVIKFPMLIEAFRQIE -NKTLNPDALVYIENTMRVGGAGIISYLTNLNYSYKNLLELMIIVSDNTAANIILDKI-GS -QNVNTLSTRLKCMETYIGRKFMDQKAQ-MNGIENYTSAVDMVHYLELIAKPNVISENSRM -QILDILSHQQF-KDKLPYYLDDNIDIFHKTGELP-GIEHDVALLNYKEQT--VYAVILTE -GFENNAHGKKYISEIGKYLIEY- ->[subseq from] Serine hydrolase n=1 Tax=Rummeliibacillus sp. TYF005 TaxID=2058214 RepID=A0A3N6BPB9_9BACL ---QLAVECQKIINSYDYQVSVAIID--GEQSF-LYKEDQLFRAASTIKIPILLASYLNLN ----DRLDTVATIPEELIVEGAGVIPFITGKLFTYRNLMELMIIVSDNTASNALLHSN-SM -HHVNHLMQKIGCKGSKIERYFMDE-SAVQNGFDNYTTAKDMILMLQQIGEGGVLNDSQRS -DALRILGNQQF-EDMLPATFDEEIRYYHKTGGLT-GVDHDVAIINYRQKK-LYVAVLTQG -WN-DGFTGKKCIAEIGKVIVDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium amylolyticum TaxID=1121298 RepID=A0A1M6KVX9_9CLOT -------EIKKYFESRIGNYSFYFEDLNSGFVY-GYNENVKMTAAGCMKLPIAIALLKEVE -NLNFNLNDKILIGQEDKVYGTGILHEFLEREYTLYELMVAMLIQSDNTASNKIINLV-GK -EKINESIREMGLKNTVLNRRTSDEIYD-DNNDENITTSYDLCKCWKILFEKKYLNQELSD -MLIDILKRQQL-KNKSALYIPDDLKISNKTGDKK-AVENDTMFINIEKGT-FAFSVMSNE -IPNS-VYGIVTIAKAGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NBRC 110035 TaxID=1547867 RepID=UPI0005A6007A --------------------GAGAWAEPDGREV-GVGADDPVVLASIFKVLLVLEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLIWTDAAGPPEACA -FVRDLMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HDASRPTVDAAMGRAAETA---- ->[subseq from] Serine hydrolase n=2 Tax=Kribbella soli TaxID=1124743 RepID=A0A4R0H9A8_9ACTN -----NARIRGIFEDAGVRGWMHAVSLDEPEASvELDADAVVPMASVYKLPLLAGFCRLVD -LGELDPRERVTLEPSARTAGPTGLSAFADPVLSLRDLALSMATVSDNASADALLDIV-GL -RRLAEILESFGLRRTWVRRGTAANLRVYEAANASAASARDLTLLLRRLWAGELLSASQTE -FVKTTMHRQVF-LNRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVFTHA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Gordonia rubripertincta TaxID=36822 RepID=A0A222TD73_GORRU ----VDRGVAEVLADAGCSGWVHAATIGSPQIEySFDADAPVVLASVYKLTVLISLCRSAD -RGDIDLASSIRVDPTQWAQGPTGLAAFGDPVLSRRDLATSMMTVSDNVAADVILDEI-GL -ARVREDLVSLGADSTRIVGGVAELHEAYDAAYSSSSTPRDCTTLLSAVWTDRAASAEMCA -FIRDTMRRQVF-TARLASGFPRRVTVAGKTGTLV-AIRNEVGVVEFPGELPVAVAVFTLS -ARPALPHVDRAIGEVARTVVT-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ280 TaxID=2586994 RepID=UPI001422ECD5 ---------------------------DGGREV-AVRADEQVVIVSIFKILLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLSRTRIVGGPRQLAEVFDPAQTTSSTAREITRLLGLIWRDEAGPAEACA -MVREWMSRQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARM -ADTRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8U5W9_9BACT ---RLEREIERVSKIAGGVVGASAVHLETGRKV-SLHGDERFPMASTFKIPIAVQLLHRID -AGEVKLDQMVELRASDLHPGSGTLTDLFSKPLSVRNLMELMLLISDNSATDILLRLAGGA -DAVTTRMRGLGITGINVSRPTARLIADREGVPENQWSPEMWTKLL--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Lactobacillus nasuensis JCM 17158 TaxID=1291734 RepID=A0A0R1JGY3_9LACO ----------------PARWTVAVRALNGGAYVaDWTPASHQFSASTIKLYILIRYYQLLQ -AKQINPSTQYTLRQQDVVQGSGVMLHKLGTTYTLQELVNLMIRQSDNIATNVMMDEVGGF -AAVNKTIAQVPDHETSLERKMMDTSH-LENGKANRINAEEAVDTLLKMKQGKIVSPAADK -AMLALMLHTKN-RTKLPSQLPTGAVAYNKSGESNRGIENDMAIIDYRGQT-FAVCALIEM -DGEHDA----------------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO12t TaxID=2650410 RepID=UPI00124B8353 -------------------------------EV-AVRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIAGGPRHLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA -MVRGWMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFVRA -TQTRRIDVDLAMGQAARAAV--- ->[subseq from] Uncharacterized protein n=2 Tax=Lactobacillus fuchuensis TaxID=164393 RepID=A0A0R1RTQ9_9LACO ------------------------------------------------------------- -------------------------------DSTVTTLITAMIQYSDNNATNQLIDYV-GM -PKINQYLQEQGYQQTKLERRMLD-NAARAQGLENVTSVTDTLNFLKQLYQDQTRYPA--N -QMLAILKGQQV-RTKIPSQLPAGTVVANKTGELAD-VENDIGIVYRTDN-PYIIVVLTNQ -VSNTS-AERQAIGQLSLAA---- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BF803F --qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRADLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPQPLRT -FALDLLADQRERAHS-LAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=UPI00086F0925 ------ERIREVFAGAGAEGLLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL -DTVRLLAGELGLGGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA -HVRDLMMRQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGSYAVSVFART -RDASRPVVDAAIGASARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus equicursoris TaxID=420645 RepID=UPI0012B2E782 ------------------------------------------------------------- ------------------------------------------------------------- -------ARTLGVSPSSFAQDYDSAFDAYEASGENVGTLRAYGDLLASLHHGGMLDREQRQ -TLREVMQRTRSGEQRLKRGMGREVTLAHKTGTQHR-RSCDAGIATRDGVQHWVIVACSRG -PL-ALSAHEQALTRVGEALHD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Dormibacteraeota bacterium TaxID=2052315 RepID=A0A2W6BF60_9BACT ----FVQNLQSYLSRAGGSYGVYVESLKSGATV-GAGQDSGLEAASVIKVPEALYLLHQVD -AGQVKLIDEVDLKDGDFMSGTGTLTAHTGDKFTVQDLLTLLIRQSDNTAWRALDRIL-GI -AAVDAFAASIGAPD---------CHQV-----SDNCTAREAGRMLSQLARGRLLTPGSTQ -LLMGLLETTVF-NDRINYYLQ-GVTVAHKVGMDG-GVINDCGVAFLPGD-PLTICIFTTT -GDPN--LGVQVIRDVTRAAVHYy ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=A0A1H2G6C9_9PSEU ---EITEKINERAKEVGVRVRLHAAEIDGSRQI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA -DVRRWMDLQVW-PHRLRSGFPDGIRVGGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=halophilic archaeon NEN6 TaxID=2558241 RepID=UPI0010C18EC3 --nELRSTARTIDERLDGRLGIVVCDVGSDRAIeAIRSRNRFGAASVVKLPILYALYRTYD -GRLEALERRHPIAPENRVGGAGLFHLLSDPTPTVEDLATAMIAVSDNAATNELIDHL-GF -DAIDEGAADLGLEGTHLGRKMMQTPASNGHRYVNWVTPQDCAALLSDIHRERTLSSAAYE -RLARPLAHQHD-GSMVPRYLPPNAEIRHKTGSLPS-VAADAGLLTVGER-TVAYAICCDG -LER-RGDGVDAIAELGEGVY--- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces hundungensis TaxID=1077946 RepID=A0A387HEV3_9ACTN -----RSRITAAFTDAGLSGALCATDIDHGTTV-TLAADTPVSTASVHKLCLVATLYREAA -AGRLDPTTPVDIPAAARAPPTGLAVMRDAARLSLRDLASLAIAVSDNAAADILWDHL-GL -DTVNATMAALGLPRTIAVHNQAGLYAVLDPHRTNRSTPREITALLTAIWRDDLCPPPWAE -ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA -ASVTLPAADAAIGRAARIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_40CM_4_69_19 TaxID=1805078 RepID=A0A1Q7HHB3_9CHLR ---DLIRQLDGLVASFPGGAGVWVSDPNVPTPLfMHDPDEQVIAASLYKLGVLAEAERRVE -AGQLHYNDQVVIQPEDVTADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG -ANVDVTLQNAGIADFHVALDESE---------DHWATPRAVGMFFTLLARRQLISPAASD -RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA -LD---EDADNFISSVGASVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK438 TaxID=2512151 RepID=A0A4R2PXT4_9ACTN ------TALRAAFTDAGVTGRMHALDIVSGAEL-DLYGDESVCTASIHKLPLLVTLHEQAA -AGDLDLTEQIDCPPLGRPAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL -DAVNRTAARLGLSRTIATHSFGEMMAALDPAWANRSTPRELTRLLAAIWRDEACTPENGD -AMRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEAGVVEYPDGGQYAVAVFTRT -LSAIVPAADAVIGTAARIAVD-- ->[subseq from] serine hydrolase n=2 Tax=Pseudonocardia TaxID=1847 RepID=UPI000919FCFB ----------------------------TAREV-GVGAHVPVVMASVYKVFVLVAYCRAVD -AGTIDPREPVVVPVRRTPGITGISALADPVTMSWRDLVTSMVTASDNAAADVVHTRV-GR -DRVSALPAELGLGGTRIRGGTDDVFAALSPVYGSSTTAADTTALLGMLWRGELASDGSTA -FARRVLGAQIW-PHRLRAGFPAAARVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVYTHA -ARSDVPRADAAIGAAARVAVH-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536Q9H7_9CHLR ---DLIRQLDGLVASFPGGAGIWVSDPNVPTPLfMHDPDEQVIAASLYKLGVLAEAERRVD -AGQLHYNDQVVIQPEDVTADGSFEE--AGTQLTLDEALEAMITISDNGAALALWHIL-GG -ANVDVTLQKAGIADFHVALDESE---------DHWATPRAVGMFFTLLARRQLISPAASD -RMLARLERQQI-NNRLPAQLPAGVVVAHKTGNLV-GATHDAGIIYTKSGPRVVVAMTWDA -LD---EDADNFISSVGASVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium sp. CAG:82-related_59_9 TaxID=1897006 RepID=A0A1Q6Q8V5_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS -RGKASLTEEIEYQPEHFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL -DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD -FH--------------------- ->[subseq from] serine hydrolase n=1 Tax=Serratia TaxID=613 RepID=UPI000D154BC5 ------------------------------------------------------------- ------------------------------------------------------------- -------MRSIGDTVTRSDRYEPELTVNPVDDLRDTTTPDAMSKSIKKILTGAVLSDSSKA -QLKEWMVNNKVADNMLRASLPKGWKIADRSGASDYGVRGITSMVWSNNHDPVFISIYVRK -ADTSLDERSAVIRTLGSHIFDEy ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. N1-1 TaxID=2682541 RepID=UPI00135C0FE9 ----VKEKILECFHGLEGNQSIYVST-PDG-EI-ALHADQPVSSASIIKIAILLEALRQVD -DEQLSIDQVVQIDNVNYVGGAGVINHLSRDHWKLADLLKLMIVSSDNTATNQLIDLV-GE -DHINHTMKAAGAFHSKLMRKMMDRNA-LKAGVDNMVSGKDTYLVLREFVTQHLLSKSSME -WGVEVLFQQQF-KDKFPSKISKEKLLAHKTGELN-GVEHDAGILFTSDG-PVVYAFLTAG -LL-ENRYGREAIANAGRLLYDFy ->[subseq from] Serine hydrolase n=1 Tax=Embleya scabrispora TaxID=159449 RepID=A0A1T3NPC7_9ACTN -----TQRIRAIFDAARVDGFLHVRDLDTADEI-AYQADDPVVLASVLKVPIVLEYARQAA -DGRLDRAGRHLVTAADREGGIGTDGCMYDVEMSARDLAFMMITQSDNAATDIVLRLV-GR -DNVRATLDALDCRDTSVTGCKDLFQSVRDPKRTAATTPREITKLLAAIWRDEAGSAEACA -EVRDIMGRQIW-PHRLASGFADEIRVSGKTGTLW-GVRNEVGVVEYPDGKRYAVGVFLRL -ESFRAPAADASIGLAARAAIDH- ->[subseq from] serine hydrolase n=1 Tax=Alcaligenes xylosoxydans xylosoxydans TaxID=85698 RepID=UPI00083AFAE8 --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARQADRMQPSASIIKVPILLALLEAVA -KGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATCLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Actinocatenispora sera TaxID=390989 RepID=UPI00068AAC5F --------LTDTLDAAGGTVSVYAGPLSGPPAF-TRLPDEPHYAASTMKAAVLATAYRLAE -AGAVELDEPLAVHDEFTSAD---AWARLGDTAPLRWLLRRMIIRSSNLATNLVLERI-GT -HALANTLRDAGATRMVVARGIEDAA-AVDAGLDNLVTAGDLARLLAAIADRRIASARHCD -EMMGILLDQEC-TEDLAAGLPPGTRIAHKNGWVER-IRHGVGVVLPDDAPPYAIAVCTTT -DLPD-AQACALLAEVSAAAWA-- ->[subseq from] Serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=A0A2M9H1M2_9BURK --qHVDAALTPLLAATPARVSLSLRDLDGGVVL-ARQADRMQPSASIIKVPILLALLEAVA -KGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLL-GF -DAINQWNQRANLEATCLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPPPLRT -FALDLLANQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] Beta-lactamase related protein n=2 Tax=Catenulispora TaxID=414878 RepID=C7Q8V4_CATAD ----ASARITAAFADAGVTGQLHALDIDTGASV-SVAATQLAATSSLHKVCLLAAFYREAA -AGRLDRTRQIDITAAERTPLSGIAVMRDAVRLSLRDLATLVVAVSDNAAADILWREV-GF -ATVNRTMAELGLSDTVAVHSMADIRDVLSPTQTNRSTPRQMAELFAAVWRDEVCTGDLGE -ELRAVLGGQAW-THRMSSGFPDDVRVSGKTATLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASAVLPAADAVIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009A05AA5 ---------GAVLAQADAGIQLHAVDLDTGGEV-AVAADQQVVIASVAKILIVLEFARQAA -AGQLDPGAHVTLRAEDRLGGWGIAGCADDVDISLRDCAYFAMSLSDNTAADALIRRV-GG -DAVRMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGTADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GMHMEAGVVRYPDGRRYALAVFATA -RDTRPADLDETIGRVAHAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Kribbella shirazensis TaxID=1105143 RepID=UPI00141DDEA4 -----SARIRAVFEDAGVRGWLHAVALDEPESTvEVDADGMVPLASVYKLPLLTGFCRLVD -LGELDPRRRVTLEPSERTAGPTGLSVFADPVVSLRDLALSMMTVSDNASADALLDIV-GL -RRLAGMLESFGLRRTWVRRGTAGNLRVYEAANASASTAREMTLLLRRLWAGDLLSPEQTE -FVKATMHRQLF-LHRLASGFPDEVRVAGKTGTFG-ALRHEVGVVTLPGGAAFAVAVFTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. 06-235-1A TaxID=2022508 RepID=A0A260BMU9_9NOCA ---TTDQQLRAVFADAGCRGWVRAERIDGTGTVvDIEGDDPVVAASVWKIVLLVAAARAFD -EGFLTATDSVRLVPAQCSPPTGIASYADPVTMSWRDIARSMITVSDNAAADALLGAL-GL -NAATRVIDDLGLKHTRIVGGTKALGDGFDPAYTSCTTPRDSNAVLRAIWSGAAASSEQCE -YMKHVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGEEPVAVSVFTRA -ARMDLPLVDQAIGSAARIAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1D8DX91_9BACT ---RLESELIAIAGEYSGTCTWSLTHLATRDHI-ARDEGRVMPTASLIKVPVLAALYAAAE -AGGFALTDRITYAQEHRCLGSGVLSKLTPGVMTVRDAAVLMMTISDNSATNMCIDLV-GI -EAINAGMRSLGLDRTTLFYRLGDRTPGLDARRMSVSTAGEMVGLMTLIAGHACVSADASE -DMLRIMRRSDY-RHELSAELPKVAWVAEKGGSFLNGVRTCAAVFHGPRG-SFVMSAFCEG -GTGRSSEGNRTIGRLGKAAWD-- ->[subseq from] PfkB domain-containing protein n=1 Tax=Microgenomates group bacterium GW2011_GWB1_44_8 TaxID=1618505 RepID=A0A0G1MA94_9BACT ------EELGKLLSTYTGTYGVFVEDLQSGFSY-GVKEDEEFPAASQMKLPIILAVYLEYE -KGNLNLDAPYTLLKSDKIEGTSLASFKDGSNFTYRKLIEFSARNSDNSAIRILWRKL-GN -ERIRESLIVGGMKNSSFE--------------NDITTPKDIGNFFSLLYRDMLLRKEQKE -ELIGFLTNTIS-EDRIPAGLPAGTRVSHKIGTED-GAYSDSGIIFG--KKPFILVVMSKG -AN--FKEAPSAIAKIAQTVWS-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993) TaxID=1114943 RepID=I2N3F0_STRT9 ------ARIAAAFTGAGVTGWLHARDIDTGAEV-DAGADRPVVTASVHKLCVLVALHEAAA -AGRLDLTEQTEIPAHGRTPGPTGLGSMLDGALSLRDAAFLMMSVSDNAAADVLLERV-GL -DAVNATTRRLGMPRTEAVETFGSFLGALDPARTNRSTPRDMTTLLAAVWRDEAGAPDHCA -AMRRILGLQVW-PHRLASGFPDDVQVAGKTGSAPT-LRNEVGVVAYPDGGRYAVAVFTRA -AS--------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces antimycoticus TaxID=68175 RepID=UPI000A38D48A -----EKRIAEVFAAADAEGRLHAVDIDPGREL-GLGVDDQVVIASVFKILLVLEFARQAG -AGQLDPRERVVITAPDRLGGWGTAGCADDVEMSLRDLAYFALSVSDNSAADALMRRI-GL -DTVRLLAAELGLGRTRIVGGPRELLEVLDPRHTTSSTPRDITTLLGLIWRDRAGPPAACA -LVRELMSRQVF-RQRLASGFPDDVLVAAKTGTLPS-LHIEAGVVRYPDGGRYAVAVFART -ASAARTAVDAAIGRAARLAV--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ309 TaxID=2035247 RepID=UPI000C6FD6D4 ---------------------------GGGREV-ALRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTAADRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACG -MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEHPDGGRYAVAVFVRA -RQTRRIDVDLAMGQAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ309 TaxID=2035247 RepID=A0A2N3ZAX0_9ACTN ---------------------------GGGREV-ALRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTAADRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACG -MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEHPDGGRYAVAVFVRA -RQTRRIDVDLAMGQAARTAV--- ->[subseq from] LysR family transcriptional regulator n=1 Tax=Propionibacteriaceae bacterium NML 150272 TaxID=2016504 RepID=UPI000B963D6E -----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD -AGLLGLDQALTLRPDGRTSGTTGISAMVDPVLSLRDALYLALTISDNAAADAIWDTL-GA -DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACT -AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL -QQETPHHRDWAIGETARLAVN-- ->[subseq from] Beta-lactamase n=1 Tax=Firmicutes bacterium CAG:145 TaxID=1263005 RepID=R6F0E8_9FIRM ---ELRDNILEELAAMEGRVGFYFKNLVTGENL-GYNQREQFLSASIVKLPLLAAMFLMRE -RGETDFREKITIKRDEKLPGCGVVSYMTGDELDIETLYKFMIVISDTTATNALYKHY-GN -DAVISALKELGLEGTQFNRAFYDSIRE-EKGIQNYFVPEEIGELLEKMYDRRLVSEKVSE -EIEKILLQQQV-NHKMGGMLPIGFPIAHKTGEEED-KSHDVGIVYVKE--PFIACFA--- ------------------------ ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Microbacterium oxydans TaxID=82380 RepID=A0A3S9X6F4_9MICO ---------AEIFADAGATGFLHAREIGDGPEV-TFGADEPVVLASVFKILVLTAFVRAVA -AGELDPTERTTVTARYRIGGVGTAGCADDVEVSWRDLALNMMSMSDNAATDIIYHRL-GG -EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTSAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA -ASLV-DRQPLVDASIGRAA---- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. 5R2A7 TaxID=2202421 RepID=A0A317CRF9_9ACTN -------RIEAIFAGAGVTASLHAVDLDDGREI-GVRADEQVVIASIFKILLVLEFARQVV -AGQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLGYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRDLVEVFDPSRTTSSTAREITRLLTLIWRDEAGPPEACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DQPRRIDVDLAMGNAART----- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora endophytica TaxID=1642495 RepID=UPI00101C7AE4 -----------------GHLHATALH-DRRREI-GVLPDEQVVLASVFKLPLVIAFAQMVD -AGEIDAAEQTTLDASERSPGPTGFAAMVDPVVSWRDAARSMMAVSDNAAADALLDVV-GL -GRVSGALDSLGARSTRIVSGIRDFYTDPANPRNNVGTCRDMTRMLEAVWRDRAASSEQCA -FIRGVMAQQVW-AQRLSAAFPDDVVVSGKTGTFV-ALRHEAGVVEYPNGESYAVAVFTMS -TRARLPAADAAIAQAAKLAVA-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3A0AT83_9CHLR ---KLQQEIERAATAFPGVVGVAVTSLRHEAGC-AVQAEEVFPAASTIKLPILVQLLMRAR -SGEADLAQRVTVPAASHVLGSGVVAYLAGPVLSLLDLAILMVIVSDNTATNLCLEVA-GL -GATNALLDRLGLHQTRVRRKMMDQVAA-VRELENVATPAELVQLLRLLDAGQP-DPQAAA -QALAILKKPK-------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BEF6870 ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Clostridium nigeriense TaxID=1805470 RepID=UPI00082D1E9C ------KEIKKYLESRIGTYGFFFEDLKSGYIY-AYNENVQMIAAGCMKLPIAVSLIKSVQ -DKKIDFLDKIKIDGKDKVYGTGIIHEFNEREYTLFELLVAMLIQSDNTAANKIIDIL-GM -ENINNDIRAMGLKNTVLNRKTTD-ERNCKDEIENMTSAYDLAQIWKHLYNGTYLNKENSQ -MLIDILMRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FSFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] LysR family transcriptional regulator n=1 Tax=unclassified Propionibacteriaceae TaxID=185283 RepID=UPI000B97B919 -----VAQIRDVWRAVDVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD -AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA -DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA -AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL -QQETPHHRDWAIGETARLAVN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Desulfallas geothermicus DSM 3669 TaxID=1121426 RepID=A0A1I6D4M3_9FIRM ---PLQEQVVAYLARQPGTYGLYFIDLNSGREF-GYNALTPFHAASTFKLAMNLYLYREVS -RGNLDIEEKLTFLNRHREGGTGILQNNSPGEYSIAQLAGYSIIYSDNVATNILLDRL-DK -NNVKDFMRSLGGQVV--------------DDERNITCPYDLALYMHEILTFS--RQPEGK -LLLNNLFRTEL-KDRIPAPLPREIKVANKIGTWPTNSYHDVAYIAHPRR-PYILVITSKD -TP-GYGATLPVIHHISEMVYEY- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A3B8U214_9FIRM ------------------------------------------------------------- -----------------------------------GSLPDSMINVSDNGAANSLINAV-GM -ESVNEFAAKNGYPATKLNRRMLEWNGT-----ENYTSAADCGKMLEEVLRGQYVSKRASE -RILTALKNQAR-TGKIPAGVPEEIETANKTGELDN-VDNDAAIVWSPSGT-YILCIMSAN -SG--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sulfidigenes TaxID=318464 RepID=A0A084J7J1_9CLOT ------KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVE -STNIFLDQLVTITNEDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK -DRINSIIHDMGLTSTFIKKYPSGKKED--FDNENITTSYDLCKGLALLSKGKVLNEKHSK -FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLE-GIENDIVLLNLEKGD-FVFVVMSRN -LPS-NVYGVS------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Jiangella sp. DSM 45060 TaxID=1798224 RepID=A0A1H1XRA1_9ACTN ------DDIAAALRRAGTDAALHVRPVDGPGEV-ALNPDAVSVAASTYKIAVLLELACQAA -EGTLSLTARQRVPAGRRSLPTGISAMLDDVDLSLRDLALLMMQISDNTATDVVQEVV-GT -DRIAARLKGLGLANTSFPHDCAKLVGSIAGTVGNTTTPRDMTTLVSAIWRDEAGPAAACE -EVRRIMAQQYA-PHRLSTAYRDGPAIAGKTGTFHGGIRNEVGVVDFGGGDRYAVAVYLRQ -HEYDDGAADAVIGEVARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=UPI000EAD1082 ------------------------------REV-AVRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRHLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA -MVRGWMARQIF-WTRLAAGFPPGVRVAGKTGSLP-GLHLEAGVAEYPDGGRYAIAVFVRA -TQTRRIDVDLAMGQAARAAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces marokkonensis TaxID=324855 RepID=UPI0011F0E691 ----------------------------DAGEV-AVGADDPVVIASIFKVLLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWNDAAGPAEACA -LVRDLMGRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGASYAIAVFART -RDASRVTVDAAIGRAAGIA---- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. MP36 TaxID=2604468 RepID=A0A5D0UPM4_9ACTN ----------------SGCLHVTVVD-DPAREV-AVRADEQVVIASVFKILLVLEFARQVV -AGQLDPVERVLVRAEDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTARDITRLLRLIWRDEAGPPAACA -LVRELMGRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFARS -ERLSTRDVDLAMGEAARVAVE-- ->[subseq from] Putative Beta-lactamase n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=A0A1S8S319_CLOBE -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ -EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GM -DKINDDIEAQGLKNTKLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYNSSFLDEKNSK -MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC606 TaxID=2530379 RepID=A0A4R4U5G5_9ACTN -----RDRIRDIFARAGGSLHVVPVDGPDGREV-AVEADRQTVIASVFKILLVLEFARQAA -AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAYLTMSVSDNTAAELLLRRV-GA -DVLPMLAAEMELPRTRIVGGPRQLVEVFDPQRTTSSTARELTRLLSLIWRDQAGPAAACA -TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGTRYAMAVLVRT -ERLA------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacillus sp. es.036 TaxID=1761764 RepID=A0A2A9CG90_9BACI ---QVKEKIQECFHGLEGNQSIYVST-PDG-EI-ALHADQPVSSASIIKIAILVEALRQVD -NEQLTIDQVVQIDNVNYVGGAGVINHLSRDYWKLADLLKLMIISSDNTATNQLIDLV-GE -HNINHTMKAAGAFHSKLMRRMMDRD-ALKSGLDNMVSGKDTYLLLREFVTQHLLSQSSME -WGVEVLLQQQF-KDKFPSKISKENLLAHKTGELN-GVEHDAGILFTSNG-PVVYAFLTAG -LL-ENRYGREAIANAGRLLYDFy ->[subseq from] Beta-lactamase n=1 Tax=Bacillus selenatarsenatis SF-1 TaxID=1321606 RepID=A0A0A8X1D0_9BACI ---ELRDRLSNELAGCKGRASLFLEI--EGSII-ESNSNVVYQSASLIKLLILFEALRLIE -AGKLQKDKIVTIKESDKIGDTGVLQAMKVKQLTVEDLLSLMIIVSDNSATNLLIDLI-GI -NSINSAITMIGMKNSILQRKMLDFD-AIQSGHDNFTSAADIALCLKEAVAGGSLNKHSKN -TFFSFLLQQQF-KEKLPFYLDDTLKIGNKTGELP-GVEHDCGIISYGKK-QAFIVVLIDG -LSEP-ESGKTAIRQIGKHV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 74 TaxID=1827608 RepID=A0A497W6U4_9ACTN ---------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEACA -HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART -REATRPRVDAAIGAAAAMAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. AVP053U2 TaxID=1737066 RepID=UPI000780B4C9 --------------------GAGAWAEPDGREV-GVGADDPVVLASIFKVLLVLEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPGHTTASTPREITRLLRLIWTDAAGPPEACA -FVRDLMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HDASRPTVDAAMGRAAETA---- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium tagluense TaxID=360422 RepID=A0A401URD7_9CLOT --------IKKYLETREGNYSFYFEEINSGYLY-GLNEDKEMVSAGCIKLPLAMSLLKEVQ -NGKIDLQSKIKIESGDKIHSNGIIHEFSGKEYSIVDLLIAMLIQSDNTAANKIIEVL-GM -QRIDELFKDMGLKNTKLKRITTDIKLE-QDELENTTSSFDLSKCFKLLYLKQYLNEENSD -LLIRILKKQQV-TNKLPFYAPKQIQIANKGGSLET-VENDTTLMMIEKGN-FLFTVMANN -LP-NNVYGITTISRVGKMMWD-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB02115 TaxID=1703939 RepID=A0A1Q5I198_9ACTN -----------------------------AEEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMARQIF-RHRLVSGFPDGVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] Serine hydrolase n=3 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A355AQL5_9GAMM --kTLETNLNQLCDEQPFHTGWYIKNLRTGTVL-ERHSNVVVPSASTRKIAIMMAALKAVN -EGEFSLYQPVTMASRFKNNDSGCFQHHSDFSIQLQDALVMMIIVSDNTCTGAVTDLI-GL -ESVNALCQTIGMMDTVHRYGIPGMVGYLPADKTNSTTPADVARLLELILKGVGCTTDLCQ -LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYTDDEPLFLISAYTDN -VPADHTVAYDLTARLSRLCWDE- ->[subseq from] serine hydrolase n=1 Tax=Devosia sp. FKR38 TaxID=2562312 RepID=UPI0010C12EE2 -----------LLESYPGTLSFCAENLASGARI-SWREDQISATASCIKLFLLVALFAQAE -RGQVSLDERTVVAPGDHVGGSGVLKHSPGVGLSWRDVATLMIVLSDNIATNMVIDQI-GL -EVVNQTIHALGFRQTHLVNRIDFDAIGGDIAKLAVSTAADSVACLKGLAMGTVVSPEASR -AMLDILSRQHY-VDLLPRYLPYDVSVAGKTGFFP-GFRGDIVLLGKGDE-QVVMAAFASG -ADLSFAPENAIARALGEI----- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E5Y0J7_9BACT ----LEDNIFSLMKEFDGDVSIYIKHKTQNLEI-GFNENKKMPTASLIKIPIMIKIFDKIK -KGELSLDSTVVYYQDSIGYGEDALSSFKDGEITIKKLLTHMITFSDNHASLWLQKLAGGG -ETINNWLSENNFKNTRVNSRTKGREKDKEKFGWGQTTAKEMVNLITMIRESKVVSKSYSD -KMYRHLTRIYW-DEEALSQIPANFQVASKQGAINR-SRSEVVLVNAPKGD-YAFCIITDN -QTDTDNEGFVLIRKLSKLLWDYf ->[subseq from] Serine hydrolase n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A2G6NYS6_9FIRM ---SLKARLKAEVISFSGKMCFYANDF-KGNVI-AVNANEKFEAASCIKVFILLEFYRQIF -EGKISGNEMLSYGEENAITGSGILRNDVGVTMTAKNFATLMIIISDNIATNIMIDFL-GL -DNINQTIRELGFKSSELHNKID-FEQY---EKLGTTTPRDYGKFFEMLYKEEFWSPEISK -QMLEVFKKQHY-QTMLTKNLPQYIYVASKSGSMD-AARNDGGIIHTPYGA-YVLTIFTKK -FKDP------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. EN16 TaxID=212773 RepID=UPI0008519E02 -------------------------------EV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] Beta lactamase n=1 Tax=Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) TaxID=405948 RepID=A4F9H0_SACEN --------------------GRSGSETGPGREI-GIGADDLVVTASVYKLPLVVALCRAFD -AGRIDPRARVRLNPPSCTPGPTGLATFLDPVVSWRDMAASMIGVSDNTSADVILGEV-GL -DAVAETLAELGLERTRVVGGTADSHAAYDPAYASATTPREMTRLLDLIWSDAVASPQQCA -FIRRLLSNQVW-MHRVRAGFPRGVHVAGKTGTVG-AVRNEVSVVEFEGEVPVAVAVFTLA -ARADLPKVDAAIADCARIAVN-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_02_FULL_40_13 TaxID=1798384 RepID=A0A1F6A9F8_9BACT ----LLESLADDIQKNGGTFSVYIFDMKANKGF-GINENMVITAASVTKIPILATLYKMAG -EGKIDLEKIIIPQPSDIQNGTGSIRYDPSDTYSIKTLARLMMEKSDNTAAYLFAQIIIKR -SNIQNQVDAWSLTQTDIS--------------DNKTSVYDMNLLLQKIYHGEVTSPALTK -EMLDFMDVSDF-DDRIPKGVDEGVRIYHKTGDDV-GKIHDVGIVDLPKR-PYYLGVMTTD -MT-NAEETKKTIAKISRKVFD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5CTR9_9ACTN ----VESRIRTAFDDAEVQGYFFAREIDGDRTI-GVAADEPVCLASVFKIPIALAYAREAA -AGRLDRTERHSVDPHYRDGGIGTSGCADPIEMSLRDLVHMMLTMSDNAATDVVLARV-GL -DTVNGLLAELGLRRTHLVGGCLELTGVCVPERTTRGTARDIAELLVQIWRDEAGPAEACA -EVRAVMSQQIW-PHRLWSGFDDSYRVAGKTGTLP-GWRNEAGVIEDRDGGRWAVAVFTRS -DRPDNSRADRVIGQVAALAVDE- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. AVP053U2 TaxID=1737066 RepID=A0A1D2IA47_9ACTN --------------------GAGAWAEPDGREV-GVGADDPVVLASIFKVLLVLEFARQAV -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPGHTTASTPREITRLLRLIWTDAAGPPEACA -FVRDLMARQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HDASRPTVDAAMGRAAETA---- ->[subseq from] Serine hydrolase n=1 Tax=Embleya hyalina TaxID=516124 RepID=A0A401Z090_9ACTN -----AQRIRAIFDAARVDGFLHVRDLDTADEV-AYQADDPVVLASVLKVPIVLEYARQAA -DGRLDRAGRHLVTAADREGGIGTDGCMYDVEMSARDLAFMMITQSDNAATDIVLRLV-GR -DNVRATLDALDCRDTSVTGCKDLFESVRDPKRTAATTPREITKLLAAIWRDEAGSTEACA -EVRDIMGRQIW-PHRLASGFADEIRVSGKTGTLW-GVRNEVGVVEYPDGKRYAVGVFLRL -ESFRAPAADASIGLAARAAIDH- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. YIM 98842 TaxID=2663533 RepID=UPI0013DB6BA4 --sELKDQITEEIEEISEKVSIYIET-EE-GII-AIHENTKRRAASLIKVPILMEGYRQIE -NKEIHPDTLIYIDQNMRVGGCGVISYLSSGHGSLQNMLELMIIVSDNTATNVLLDKL-QI -DRINKLARSIGCSETVIERMLMDKE-AQAAGLDNYTSAKDMVYLLKTIFENDHYTENSRL -HMLEILANQQF-KHKLPLYAEDGIKFYHKTGELD-GVEHDAAIMEAKGR-ILYAAVLSEN -LF-PNARGQRHISSIGRLLVEY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=UPI0010570F93 ------------------------------------------------------------- ----------------------------------------AAARQRHNTATNLPLDLLGGP -TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE -RLTTSLVVNTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces lividans TaxID=1916 RepID=UPI0011127D48 ------------------------------------------------------------- ----------------------------------------AAARQRHNTATNLPLDLLGGP -TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE -RLTTSLVVNTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora humi TaxID=745366 RepID=A0A1C5ISC4_9ACTN ------QRVGEIFGRAGLSGCLHVADVDDAREV-AVGADERIVIASVFKILLVLEFARQVA -AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVPSMLAAELGLPGTRIVGGPRHLVEVFDPERTSSSTARELTRLLRLVWRDEAGPPAACA -TVRELMSRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVLART -ERLDTRDVDLAIGEAARTAVD-- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Dethiobacter alkaliphilus AHT 1 TaxID=555088 RepID=C0GGV0_9FIRM ----------------DKRLMFSFYDFATGETL-SHNGDRVIFPASMIKTLYLAVFLEEVK -HERQSLDAEYILQQRDKYAGSTIVYEPSGTKVTHAELLSLMVAESDNVATNIITNIL-GF -QHINDRIKEYGLKNTRAHRKMFDLESD---RPHNLTTLDDLIQLLILIEEQALFDGPLHE -KALDIKRGSSK--CRIGRYAPEDVKVANKLGNTAT-ILADMAIIHFPNREPIALAVMIQG -KNIDDEANAELMGRLSEHIINYy ->[subseq from] serine hydrolase n=1 Tax=Anaerocolumna sp. CBA3638 TaxID=2696063 RepID=UPI001373A0BA ---TLEERIKAELASYNGLMGVYVNDF-KGNKV-EINTEEKFETASCIKTFILGTLFDEVE -KGNKSLTDILTYTKENEIDGSGVLRSLDGVQLTAKNMATLMIIVSDNAATNIMIDYL-GL -ETINNFIKSHGFMDTVLHNKINFVMY----DQLGTTTPKDYGRIFELICKEELISTNASR -QMLEIFKKQHY-NSTLTKSFPQYIYVASKSGSMN-ACRNDGGIISTPYDK-YVIVLFNKN -FTDPDHPATVFSSKVSRLIFDQy ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000370BF08 -------------DRMPSTVSTYLARLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AGRLTPDTAVPVRNEFDSAQPGAAWDRLGGTAPLGWLAERMIVRSSNLATNLLLEQV-GL -PAVADVWARAGARHSSTGRGIEDFAAR-AAGITNPVTAADLAALLRDLALGALATPESCT -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG -DHPDDEEACQVIADISARAF--- ->[subseq from] Serine hydrolase n=1 Tax=Pedobacter sp. BS3 TaxID=2567937 RepID=A0A5D8YMA2_9SPHI --kKLQTALEALVKNFHGDVGIYVKNLKTGSIA-AIHANTIFPTASMIKVPIMIGIADKIE -RGELHYNDKLLYRDSLSYNKDDIIGCLADSTIDLSKVQLLSITTSDNTASLWLQQLA-GS -DNINNWLAAHGYEHTRVNSHATGREQYREKYGWGQSTPREMAGLFEQIRNGHVVSPAASE -RMYRNLIRIYW-DGIALSQIPPYIQAASKQGAIN-ASRSETVLVNAPHGD-YVFSVITKN -LQHAANEGWQLIRDVSALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Aminiphilus circumscriptus TaxID=290732 RepID=UPI000478580A ----FEERIRAEIHNFSGLLGLYADDLR-GNVI-ALNADEPFESASCIKVFILAELYRRIA -EGSVAPDQLLSCGEEHFVVGSGILRCLESGVLRVKDFATLMIVVSDNIATNLLIDFL-GI -DAINTTCRALGFPNTVLHNRID-FARF---DKLGTTTPREYGEFFGKIARNELWSAEACE -DMRGMFKDQKY-NTLLTKGLPQYFFVSSKSGSMD-ACRNDGGIVSTPYGN-YVVAIFTKD -FKDSDHESFRFGSRVSRLLFDQ- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A358EEN8_9BACT ---HLAGEVSRLAEHALGTVGVAAYHLETGRWM-TMNGEERFPMASTYKVPIATQILAMVD -QGDLALTDMIEIEQEDVYLTSSAISDLLDDPLSIHNLLELMLQISDNIATDILFEIAGGA -EEITGRMVEVGADGIRVDRTTWALIAAFNADPQDTATPLAMAQLLRK------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces palmae TaxID=1701085 RepID=A0A4Z0G0D7_9ACTN ---------------TGTRLRVHARCVDCGRET-GSAADEPVVLASVVKVLLVLEFARQMA -AGQLDGTERVVVPSAARLGGTGTAGCLDDVRMSLRDLAGFALSVSDNAAADVLFDRV-GV -DTVGLLAAELGLHRTRVVASPSTLLAIRDPLRTNGSTARDMTRLLTLVWTDRAGPPEACA -RLRRLMAHQVN-WHRLAAAFPEEVAVAAKSGTLP-GVRNEIGVVRYPDGGRYAVAVFLET -PAERRADLDRLIGATGHTAV--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003767360 -------------DRIPGTVSAYLARLDAGPTW-TRHPDTTHYAASTMKMAVLVALYRALE -AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG -DHPDRSADTQLLADVSAHA---- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora deserti TaxID=2070366 RepID=A0A2W2CN06_9ACTN -----TQRIGEIFDRVGVTASLHVVDLDGRREV-AVRADEPVVIASIFKILLVLEFARQVV -AGQLDPRERVLVTAGDRLGGWGVAGCADDAELSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLATELGLPRTRIVGGPRQLVEVLDPEHTTSSTPREITRLLGLIWRDEAGPAQACA -MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DRTRRIDVDLAMGEAAHA----- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC401 TaxID=1848324 RepID=A0A5R8P4L2_9ACTN ----------DHARELGADIWLHARDLATGRSV-GVGESTPVVTASVLKVPVALELARQSV -AGEVDLTERITVPPGGVPSPYGLSVQRDDTVISYRDLAHLMIVISDNVATDLVIDRV-GK -DRVAALLAELGLTATAVPQDCAEILAALVPERTCRTTPEEITRLLAGIWRDEAAPPEACA -LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEYADGGRYAVGVFTRA -GDPNAPHLDALIGWAAAN----- ->[subseq from] serine hydrolase n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=UPI000D631CF8 -------EIKRYLESRIGTYAFFFEDLESGFTF-GYNENVQMTSAGCMKLPIAVSVIKYIE -DGKGTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDMV-GI -DSINEDIIAQGLKNTKLNRRTSDERAA-SSGVENITSALDLAKIWRHLYNSSFLNKKNST -MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKTS-VENDTALIHVQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase, putative n=1 Tax=Deinococcus proteolyticus (strain ATCC 35074 / DSM 20540 / JCM 6276 / NBRC 101906 / NCIMB 13154 / VKM Ac-1939 / CCM 2703 / MRP) TaxID=693977 RepID=F0RM06_DEIPM -------------SGFTGTVGLLIQDEAGRDLC-SLNAEAVFPAASLIKLPLLVLGLQAAQ -RGDVALVECLPLPAAEHVPGAGVLHELDAGLLTWRDLLTLMIVVSDNTATNMVIERL-GL -ERVQVALPGLGLTHTRLVGKLQQQNAAQRRGERNQTTPRDMLRLLQNLRQGEYLDASYTA -LALDILGRQQL-RDLMGRRVPCGYPVLSKSGELP-GVHHDAGWLLTP--RPLAVACLSLG -GEDP------------------- ->[subseq from] Serine hydrolase n=1 Tax=Faecalibacterium prausnitzii TaxID=853 RepID=A0A329TIH4_9FIRM ---TLEKRIAAELYSYQGKMSVFVDDL-QGHTV-EMGADEEFETASTIKAYILAVLYLQAS -RGKASLTEEIEYRPEYFVDGSGMLRAGVGAKLKVKDTATMMIICSDNIATNMVIDYL-GL -DTINACIKELGFAHTVLHNPLH-FDR---YEKLGTTTPRDYASLFAQVAKGTLVSAEASA -EMLAIFRQQHY-NTMLTHDFPQFIWVASKSGSMN-ACRNDGGIIHTPYGE-YVIVLMNKD -FH--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora purpureochromogenes TaxID=47872 RepID=A0A1C5A863_9ACTN ----AEQRVEEIFARVGGSLHVVPVDGPAGREV-AVRADEQTPIASVFKILLVLEFARQVA -AGQLDASERVLVRAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELHLPRTRILGGPRQLVEVFDPAHTTSSTAREITRLLGLIWRDEAGPAAACA -TVRELMSRQLF-WTRLASGFPAGVRVAAKTGTLP-GLHLEAGVAEYPDGSRYAMAVFART -DRTRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Achromobacter ruhlandii TaxID=72557 RepID=UPI0007BFA1C6 --qHVDAALTPLLAATPARISLSLRDLDGGVVL-ARHADRMQPSASIIKVPILLALLEAVA -NGRYALEQPLALPAAERAGGTGILAQLPSVALSLAELARLMIVLSDNVATNALIDLS-GF -DAINQWNQRADLEATRLQRRMMDAAA-REAGRDNYTSAGDATAALCWMLRDGMLPQPLRT -FALDLLADQRE-RAHFGAALPAPAHLASKAGQLP-GLRHDAGILTVADR-SVALAVLADG -FT--------------------- ->[subseq from] Beta-lactamase n=1 Tax=Agromyces fucosus TaxID=41985 RepID=A0A4Q2JQH3_9MICO ---ALLRDAAEVLRSAGLRASIVVRDLGSGREL-SIAGDDDYPLASVVKLPLALAVLQRID -EGRLDPARPVTLRPDDRTPLVGYCRFQHPTTVSVEDLLYMAVCLSDDTAADALFDLC-AP -AAVTASLRETGITGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRAPALAP-QRD -RLRGLLAMNVM-RQRLAPDLEDDAVWHSKTGTFLH-LRHEIGVLEHADGRAIAIAVLSES -SVQRQPAAEQALGLAAKLL---- ->[subseq from] serine hydrolase n=1 Tax=Rummeliibacillus pycnus TaxID=101070 RepID=UPI000C99E755 --qQFATQCHEIIGQYDAKIGIAILD--GKHTF-YHQEKAIFRAASVMKIPILLTSYLTLS ----KALDTVAVLPEELIVEGAGVIPFLTGNLFTYRNLMELMIIVSDNTASNALLKAI-SM -EKVNQFMQDIGCEDSKIQRYFMDENAV-LKGLDNVTTAKDMIMILQQIGENNFLNEKQQI -DALRIMGNQQF-REMLPSTFDEEIHYYHKTGGLT-GVDHDVAIIQYHEKQ-LYAVVLSQG --WEDGFTGKKCIAEIGKAIAEY- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC213 TaxID=2530378 RepID=A0A4R4R2P9_9ACTN ----VRERIRDIFARATGSLHVVPVDAAEGREV-AVEADRQTVIASVFKILLVLEFARQAA -AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAFFTMSVSDNTAAELLLRRV-GA -DVLPMLAAELELPRTRILGSPRQLVEVFDPEQTTSSTARELTRLLSLIWRDQAGPAAACA -TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGSRYAMAVLVRT -ERLA------------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. rh34 TaxID=2034272 RepID=UPI000BEF5FC7 ------KRIREVFAGAGAEGLLHAVRVEGDGEV-AVGADESVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL -DTVRLLAEELGLDSTRVVGGPRDVLEVLDPLRTNAGTPRDITRLLRLVWRDEAGPPEACA -WVRELMGRQAF-RHRLVSGFPDEVAIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. H-KF8 TaxID=1727216 RepID=A0A1A5P102_9ACTN ----------------------------GGREV-GVGADDPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL -ETVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS -LVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRHPDGECYAVAVFART -HA-LAASRPTVDAAVGRAA---- ->[subseq from] serine hydrolase n=1 Tax=Brachybacterium sp. sponge TaxID=1775432 RepID=UPI0007A4E095 ---------------TEVRIAHCLLD-ADGAVLsAARAEEPFYAASTIKLHVLLAVLRAAE -QGALDLDTELPATRTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL -DAVASVARELGLGATRVERLIGDAA-ALERGQTNETSAADLARTMHHLVAGPGLAADSRE -LALAALRAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAFVEDPAGGPRLLAVMTAG -LAED-EADARITALAA------- ->[subseq from] Beta-lactamase n=1 Tax=Lactobacillus odoratitofui DSM 19909 = JCM 15043 TaxID=1423776 RepID=A0A0R1LSQ4_9LACO ----------------KWTVAVASLDGGHQAYMtNWSPGRAQSSASTIKLFILIRYYQALK -RGLIHANDTYTLRQADKVSGSGILHKKVGTQYTLRQLVTLMIEKSDNIATNVLIDKLGGF -SGVNQTIAKVGTHYTSLERKMMDIS-NISNGKANRINAWEAVQTLLSIYQGQVIDATTDQ -AMLAPMLKTEN-RTKLPAQLPEGAVCWNKSGESNRGIENDMAIIKYQGH-VFAVAALIEL -DGATQEQTDSQVAAIAR------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces kaniharaensis TaxID=212423 RepID=UPI001296EEF8 ----------------------HARDLDTGADI-ALGADTLVSTASVHKLCLLVTLFREAA -AGRIDLTRQLDIPAAGRTAGQTGLAAMLDAALSLRDLAYLTAAVSDNAAADVLWDEV-GL -DAVNRTMAELGLTRTVAVHGFRDLIAVLDPTFTNRSTAREMTALLAALWSGEACPGEPGT -ALRRLLGLQVW-PHRLAAGFPDDVRVHGKTGTLPT-LRHEVGVVEYPDGGRYALAVFTRA -AATSLPAADAAIGTAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Desulfallas geothermicus TaxID=39060 RepID=UPI000B809644 ---PLQEQVVAYLARQPGTYGLYFIDLNSGREF-GYNALTPFHAASTFKLAMNLYLYREVS -RGNLDIEEKLTFLNRHREGGTGILQNNSPGEYSIAQLAGYSIIYSDNVATNILLDRL-DK -NNVKDFMRSLGGQVV--------------DDERNITCPYDLALYMHEILTFS--RQPEGK -LLLNNLFRTEL-KDRIPAPLPREIKVANKIGTWPTNSYHDVAYIAHPRR-PYILVITSKD -TP-GYGATLPVIHHISEMVYEY- ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Amycolatopsis TaxID=1813 RepID=A0A178XF32_9PSEU ------ETIVRRAEEVGVEVRLHAAEIDGTRGL-GIGEDVAVVPASVFKVPIALELARQAA -EGALDLGARITVKPGHPTPPYGLATFRHEVQMSWHDLAILMIGISDNVATDLILAEV-GK -AAVNDTLRRLGFTRTVVPQDCGELLAALQPEKSCRTTAAEMTRLLGLIWRDEAAAPEACA -DVRRWMELQVW-PHRLRSGFPDRVRTSGKTGTLP-AVRNEVGVVEYPDGGRYSVAVFTRA -GDSRVPERDTFIGFAAATAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC721 TaxID=2530380 RepID=A0A4R4LLI7_9ACTN ----VRERIRDIFARATGSLHVVPVDAAEGREV-AVDADRQTVIASVFKILLVLEFARQAA -AGQLDPTERVVVTAADRLGGWGVAGCADDVEMSLRDLAFFTMSVSDNTAAELLLRRV-GA -DVLPMLAAELELPRTRILGSPRQLVEVFDPEQTTSSTARELTRLLSLIWRDQAGPAAACA -TVRELMSRQLF-WTRLASGFPPGVRVASKTGTLP-GLHLDAGVAEYPDGSRYAMAVLVRT -ERLA------------------- ->[subseq from] Serine hydrolase n=1 Tax=SAR202 cluster bacterium TaxID=2030829 RepID=A0A5N9CK39_9CHLR ---ELINRMNAMCLESPFQSGWYLKNLQTNESA-NYYGDVVVPSASTRKIAILMNAMKWIH -EGKLSLDQPIRIDETQYVGNSSGCFQYLRPGVQLYDVLTMMIIVSDNTSTGIVANLL-GL -DSINEFSQSIGMIGTTHRHKLPPLDLDHSLDYTNSTTPNDVGLILELILLGTGSSKELCQ -IALDILLNQKL-NNKLPALLPKGTKVAHKTGTGAR-NYNDAGIIFLEDSPLFILTVFTEN -VPTSLADG--------------- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus odoratitofui TaxID=480930 RepID=UPI0007051717 ----------------KWTVAVASLDGGHQAYMtNWSPGRAQSSASTIKLFILIRYYQALK -RGLIHANDTYTLRQADKVSGSGILHKKVGTQYTLRQLVTLMIEKSDNIATNVLIDKLGGF -SGVNQTIAKVGTHYTSLERKMMDIS-NISNGKANRINAWEAVQTLLSIYQGQVIDATTDQ -AMLAPMLKTEN-RTKLPAQLPEGAVCWNKSGESNRGIENDMAIIKYQGH-VFAVAALIEL -DGATQEQTDSQVAAIAR------ ->[subseq from] Beta-lactamase enzyme family n=1 Tax=uncultured bacterium TaxID=77133 RepID=A0A1L5KWF2_9BACT ------------------------------------------------------------- ------------------------------------------MQESDNNACDILFSLIGGP -AAVQKDLKEWGVENMNVKYTEADTHRNHEWQYSNSARPSAVTFLFRMFDEGKILKKDTQL -FLWDMMASCATGAERLKGLLPKEYVVAHKTGTGGVSAINDAGIIVLPGGRRMAVTVFVMN -SKDSPAVCEGTIASVARWLCTEw ->[subseq from] Beta-lactamase n=1 Tax=Clostridium putrefaciens TaxID=99675 RepID=A0A381J6C6_9CLOT ------KEIKKYLESRIGDYSFYFEDLDGGYIY-GYNENVCMVSAGCVKLPIAMAILKESE -IGNISLNDKLTVSIDDKVSGNGIIHEFGEKEYTLIELLIAMLIQSDNTATNKLVDLV-GM -SKINSIFKEMDLKSTKLNRRVEKEK-DVDSTIQNITSSYDLCLCWKHLYNSTYLSKENSS -WVIRIMKKQQM-KNKLAFYIGEEANIANKTGDLT-GVENDTSFIQMPKGN-FAFTMMSKG -VPND-VYGIVTLAKSGKMMW--- ->[subseq from] Bata-lactamase n=1 Tax=uncultured bacterium BAC AB649/1850 TaxID=1037453 RepID=F6K0V6_9BACT ---DLEDDLTRVFADADVDVWLHVRDVGTGRQV-ASRADEQVVIASLVKILLVLEFARQVA -GGRLDPRERVLIRAADRLGGWGTAGCADDVEVSLRDLAYFAMSVSDNTAADLLLKRV-GP -DVLPVLAEELGLARTRIVGGPRQLLEAFDPAHTTSSTAAEITGLIAKIWCDDAGPAAACA -MVRDLMAQQVF-RTRLVSGFAPSVRVSAKTGTLP-GLHMEAGMIEYPDGRRYAAAVFART -RRTHRIDVDLAIGRAARRAVD-- ->[subseq from] serine hydrolase n=1 Tax=Acidobacteriaceae bacterium KBS 83 TaxID=1267533 RepID=UPI000364D718 ----LQSQVERIASEHHGQVSVYAKGLKTGQTV-AMKADEPVQTASVIKLAILYEAMEQIR -AGKAHWDDRVTLTKENQTGGSGVLGFFDTPTLTLKDVLSMMVITSDNTATNVAIDKI-GL -DAVNAEMGRLGLKNTWLYKKVGKPPSDQKKFGLGKTTAREMATLMERIVTNDAPPTDADH -AICNVMLRSQFYRDGVPRYLEEGSAIANKTGALDE-VRNDVDAVATKNG-LLILSIFTWD -NKTDDNEAYLTTAKIAKAIVGTw ->[subseq from] Serine hydrolase n=1 Tax=Gordonia lacunae TaxID=417102 RepID=A0A2C9ZK99_9ACTN --------VREIFADAGCSGRVHVRTIGTPVEY-CHDADTPVVLASVYKLAVLISLCRMAD -RGDIDLAASITVDPTRWAQGPTGLALFMDPVTSWRDLATSMMTVSDNVAADVILSQV-GL -PRIHDDLVELGLMNTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAIWTDRAASAPSCE -FIRQTMRKQVC-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVIEFPGELPVAVAVFTTS -ARSELPEVDRAIGEVARVAVT-- ->[subseq from] LigA n=1 Tax=Nocardioidaceae bacterium Broad-1 TaxID=408672 RepID=E9V0D9_9ACTN -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLVSLDEPIAVHPDSAVTQDPVTWEAVGSQLPLGDLVRRSLTVSGNLAVNLVLERV-GL -EEVAAVLADAGVTMTTIARGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA -EIEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Microbacterium TaxID=2609290 RepID=UPI00068B4FB1 --------------------------VADGPEV-TVGADDPVVLASVFKILVLTAYVRAVA -AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT -EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] DNA-binding transcriptional LysR family regulator n=1 Tax=Propionibacteriaceae bacterium ES.041 TaxID=1945889 RepID=A0A2A9GTU8_9ACTN -----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD -AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA -DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA -AIRDLMRRQVW-AHRLASGFPADLDVAGKTGTAGD-HRHEIGVVSYPDGRRYAVAVFTRL -QQETPHHRDWAIGETARLAVN-- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. CB00072 TaxID=1703928 RepID=A0A1Q4ZY10_9ACTN ----------------------------DAGEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGQPEACA -QVRELMARQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -RQASRTAVDSAIGATARIAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium celatum DSM 1785 TaxID=545697 RepID=L1QEQ5_9CLOT ------KEIKKYLESRIGKYSFFFEDLKSGYVY-GYNENVSMVAAGCMKLPIAVSLIKAVE -DKKVDFMDKIKIQSSDKVFGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIV-GM -EQINEDILAMGLKNTKLNRKTNDERINV-EGVENFTSAYDLSRIWKHLANGTFLNKENGQ -MLIDILRRQQI-KNKIALYIPDDVEISSKTGDKK-GVENDTALLELPKGR-FAFTVLSQD -VPNS-VYGTVSLAKCGKMMWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium saccharoperbutylacetonicum N1-4(HMT) TaxID=931276 RepID=M1MJ40_9CLOT -------EVKRYLESRIGTYAFFFEDLESGFSY-GYNENVQMTAAGCMKLPISVSVLKYVE -DGKIDFLDKIKIEEADKVYGTGILHEFDNREYTVFELLVAMLIQSDNTAANKLIDIV-GI -DRINDDIEAQGLKNTKLNRRTSDERAA-SNGIENITSALDLAKIWKHLFNSSFLNEKNSI -MLMDILRRQQM-KNKLALYIPDDYEISSKTGDKAN-VENDTALIHTHKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Megasphaera sp. AM44-1BH TaxID=2292358 RepID=A0A413R399_9FIRM -----------------TDLSVYCRPLDREEPV--VYHERVLPSASLIKLPVMSAFFRKEK -EGAVSFSENLRITSP--VE-GGSYYKWGGAMATISELIFHMIVESDNTCTNVLIDRL-GM -EAVNEEIRCLGLTHTVMQRKMMDFNAS-RDGRENMTTVSDMGRFFSLLSEGRAVDAVRDQ -RMLDILSQQED-NCILPAQLPHTVRVDHKTGELD-GIYHDCGLIYAPSR-PFIFCLMADG -VS--------------------- ->[subseq from] D-alanyl-D-alanine carboxypeptidase family protein n=1 Tax=Clostridium argentinense CDC 2741 TaxID=1418104 RepID=A0A0C1U717_9CLOT ------KEIKRYLDNRDGIYSFYFEDLKSGYTY-GLNENVQMTAAGCIKVPIAMALMKEIE -NNNFNIDDKVSITKNDMVSKYSIIHEFSEKEYTIKELLIAMLIQSDNTAACKIVNLV-GM -DRINELIKDMKLYSTEVRKYPSEN--KIDDNKENVTTSHDLSKCLRLLSNNSYLNEEHSS -LILETLKKNQV-NTGIPFYLPHESTTANKIGTLKC-VENDTALLNLPKGN-FVFTVMSSN -LP-SNVYGLTTISRIGKMMFD-- ->[subseq from] Peptidoglycan-binding protein n=1 Tax=Thermoanaerobacterium sp. PSU-2 TaxID=1930849 RepID=A0A1X2FVK4_9FIRM --qELKENIETLLSQHTGNYGVYFIDLNSGETF-DINGYGSFIAASTYKVPLNFYVYTLIT -EGKLDPNMEVQYTSQDYEGGSGSIQYDPVGTYTIRELSKKSIEESDNIASNMLMRVV-GY -DNYLNFIESLGAYVVPY--------------SDNVTSPRDLSIYMEDILNYANAHSSTAG -ELLSYLENTIY-NDRISYPLPSNITVAHKIGNLSN-VVNDTAIVFYTQK-PYILTIMGNN -VDSDNSDAYTVIREISKMVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. DH-12 TaxID=2072509 RepID=A0A2K2RSM9_9ACTN -----------------------------TAAV-TIDADEAVLMGSVYKMPLAVAYCRQVD -AGVLDPRQRVILSPQDRLPPTGISQLSDEVSMSLRDLVVMMMSISDNAAADAVLHHV-GA -AAFDDACQALGLFRTQLSDGAAGTLAVYDPAWATSTTPTEIARLLHAIWTDEAASPANCA -FIRRTMGLQPW-QHRLSAGFPDDVSVSGKTGTFGV-MRHEAGVVELADGRTYTAVVFTQA -ARADLPRADAVIGATARAAVEH- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. CB01531 TaxID=1718947 RepID=A0A1Q5D0Z5_9ACTN ------EQVGAIFERAGISGSLHVTDVDDGSRQvAVRADDQVVIASVFKILLVLEFARQAV -AGQLDPVERVLVRAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRI-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPTHTTSSTAREMTRLLGLIWRDEAGPPAACA -LVRELMGRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFART -ERLSNIDVDLAMGEAARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Mycobacterium sp. Root265 TaxID=1736504 RepID=A0A0Q8ZND6_9MYCO ---------------------------GTGRVI-DIDGDAPVVAASVYKVVVLIAAARAFD -TGRLDPHATVRVVPGDCTPGPTGISLFADPVLSWLDLARMMITLSDNAAADVLLAAV-GM -DALHDVIDDLGLASTRVVGGTAALQRAFDPAYTTATSPADTNTMLTAIWTGTAASPESTH -AMKTILSQQIW-PHRIRSAFPPDVVVAGKTGTIGP-IRNEVAVVSFPDEIPIAVSVFTRA -ARSDLPVVDQAIGSAARLAVN-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium thiosulfatireducens TaxID=150336 RepID=UPI0012433B30 ------KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVE -STNIFLDQLVTITNDDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK -DRINSIIHDMGLTSTFIKKYPSGEKED--FDNENITTSYDLCKGLALLSKGKVLNEEHSK -FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLE-GIENDIVLLNSEKGD-FVFVVMSRN -LPS-NVYGVS------------- ->[subseq from] serine hydrolase n=1 Tax=Mucilaginibacter sp. HMF7856 TaxID=2682091 RepID=UPI0012F7C8F7 --kRLTSKLQEAVQGYNGDIGIYVHNLKTGKTAtSANADTLFPTASMVKVSILCGVMDKIE -KRELQYNQKLVYNDSLLYKGEDILGSFKNGDIQLSKVTMLMITMSDNTASLWLQRLV-GT -PYINNWLNQNGFKSYRDNSRDPARQEWRAKYGWGVSTPYEMCRIFQMIRERRAISPAASE -RMYRTLNRIYW-DDKALSEIPPYVQCISKQGAVDQ-AKSETVLVNAPHGD-YVFSVMTNN -IKTDDNETAVMIRKISALLWHYy ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinofusca TaxID=47858 RepID=A0A1C5GGD8_9ACTN ----------------------------GRREV-ALRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTAADRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACG -MVRGWMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFVRA -SQTRRIDVDLAMGQAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Selenomonas sp. mPRGC5 TaxID=2593411 RepID=A0A5D6W8X2_9FIRM ---DLSRNIERILGADSSRYAIYFWRPAEEEEP-FIYQNRPMSPASMVKVFVMAAAMQEVH -DGRLSLDEKLVIREADVVGGAGVITWNIGEARSVRELVSGMITNSDNTATNMLIDRL-GM -DKINRYIAAHGYGDTKLVHKMMIGN----GGRKNFSSVRDLGKLFSRLYYHQLVGENEDR -FMELVLSGQKD-KECFNAALP-DFNIAHKTGEVT-GLYDDGGIFFGKQGD-FVLVIMDEG -I---------------------- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia terpenica TaxID=455432 RepID=A0A291RHP7_9NOCA ----------EIFEQAGVQGWLHARCLDCGAEI-GDGADEPVVLSSVVKVLLVLELGRQIA -AGQVDPTDRVRATAAYRLGGPGTSGCRDDVEYSLRDAAYLALSLSDNTAADLLFERV-GL -DNVRSLARELGLTRTRIAGALRDLLLALDPRRTTASTPREMTRLLALIARDAAGPPATCT -WLRELMSLQLN-QHRLASAFPSNALVWGKTGTLP-GLRNEIGVVEFPDGARYAVAVFTKA -RVHRLPQADRAIGTAARTAIE-- ->[subseq from] Serine hydrolase n=4 Tax=Clostridium TaxID=1485 RepID=A0A0B5Q9V0_CLOBE -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ -EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI -DKINDDIEAQGLKNTKLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYNSSFLDEKNSK -MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Haladaptatus sp. W1 TaxID=1897478 RepID=A0A1D2QGE5_9EURY --dELAATIAAYDETIDGNLGVFLGFPSGPDVVcSHDETRVFQSASTVKLPVLYALYERYD -ARLDELDRSCPLSLENRVGGSGLLH-LLDATPTVEDLARAMISVSDNAATNQLIDHL-GM -SAVNDAAARLGMDRTRLARKMMTMLEVPADEPTNATAPLDCARFFADLVCETTLSAAAYE -RMRVPLAAQKD-TSMVPRYLPYQTDVAHKTGRLPT-AVLDTGFLSVPDRRPLVFSVFIDG -VSGTETDGARATSDTGADA---- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536S7A1_9CHLR ---DLVQQLDGLVSAFPGGTGLWIADPNLPAPLfKHAPEEQVITASLYKLGVLAEAERRVD -SGELHYSDPVTIEPEDVTEDGSFED--SGVSLTLDEALEAMITISDNGAALALWHIL-GG -SNIDATLTKAGM---------PDFHVAFDDSEDNVATPHAIGTFFTLLAKRQLISPAASD -RMLARLERQQI-NNRLPAQLPPGVVVAHKTGNLA-GLTHDAGIIYTKSGP-RVVVAMTWD -AS--DDEADNFISSVGALVYS-- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=A0A330LFP3_LACSK ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNLLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] Serine hydrolase n=1 Tax=Mucilaginibacter sp. TaxID=1882438 RepID=A0A3C1BJH6_9SPHI --kELTARLQDDIKGFNGQAGIYVHNLKTGKTA-AINADTLFPTASMIKVSIQCGLMDKIE -KGEMQYNQKLVYRDSLLYKGEDILGSFKDKDIEVSKVALLMITMSDNTASLWLQKLV-GA -DYLNHWLDVNGFKVMRDNSKATGRGAMHAKYGWGVTTPYEMCRLFTIIRNGEAVSAAASE -RMIRNLGRIFW-DNIALSQIPPYIHTISKQGALDD-YRSETVLVNAPHGD-YVFSVITNN -NKTQDNEADVLIRKVSALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Brevibacterium casei TaxID=33889 RepID=UPI0011A1E2A3 ------DEINGVWTSLGAQGFLFAEDLETHRSV-GIRESARIPLASVGKVAIVAGLLDAAA -DGVLDLTRRVVVDPTTATPGTGISGLYDPVEMSLRDLAAMALSVSDNAAADTLFALV-GP -ERITALLHRFGIRSFDVVAPMSHLYDQLPDSAFNTGTVRATARLFELIHTGRLLGTEDSA -VLRDLLRRQIF-RHRIAAGFPDAVSYYGKTGTFLN-FRHEAGVIVDSDGTAYSIAIFTRS -TIATQPELDASIGYCARLAIEH- ->[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. SAI-095 TaxID=2597743 RepID=UPI001358C529 -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPITVHPDAVVGQDPETWAAVGSPLPLGDLVRRSLTVSGNLAVNLVLERV-GL -EEVAAVLADAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA -ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWID-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora violae TaxID=1278207 RepID=A0A4Q7UMU9_9ACTN ------------------------------REV-GVRADEQAVIASIFKILLVLEFARQVE -AGQLDPTERVVVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRLLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO31t TaxID=2650566 RepID=UPI00124B297D -------RIGEIFRRAGISGCLHVEDVDPGREV-TLRADEQVVIASVFKILLVLEFARQAV -AGQLDPVERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTTSSTAREMTRLLGLIWRDEAGPPAACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAIYART -ERLSTRDVDLAMGEAARAAVE-- ->[subseq from] PEGA domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535R352_9CHLR -------GLDAYLRSTGGQFGIYFLDLKTGSEF-GYHQDDLMEAASDIKIPVALYVFHQVE -ANAVKWDDKVTLEAEDFMGGTGLLQGSASAGFSYWDLLTLLIEQSDNTAWRTLQRVL-GA -DTIDAYAASIGAPD---------CHQV-----DDNCTAHESGLMLARLYRGQLLNRADTA -TLLTVFESTVF-DDRINYYLG-GLTVAHKTGADG-GVMNDVGIVYAAGG-PFLVSVYSQT -GGGT----VQPIRDVARAAYRYf ->[subseq from] Beta-lactamase class A n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=A0A2N3S418_9ACTN -----------IFDRVGVNACVHVVDVDNGREV-GTRADEQVVLASVFKILLVLEFARQVV -AGQVDPTERVLVGAGDRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRV-GR -DVVPLLAAELGLARTRVIGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRDEAGPPAACG -MVRDLMSRQMF-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAQT -QRLSTRDVDLAMGEVAHAAV--- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. TPD7012 TaxID=2171975 RepID=A0A2T7X1Q1_9MICO -------------------LHAAEIGVVDGPEV-SVRADEPVVLASVFKILVLTAYVRAVE -SGELDPVGRTTVTSRYRIGGVGTAGFSDDVEASWRDLALNMMSMSDNAATDVIYHRV-GA -EAVRQVITDLGLEGTHLVGCCEELFDVLEPARTSASTPREVTTLLNALWTDTAAPAAASA -AAREIMAQQIW-PHRLSSGFPSEVKIAAKTGTVP-AWRNEAGVVTYPDGRQYAVAVFTRA -DSL-AERLPAVDASIGRAAC--- ->[subseq from] serine hydrolase n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=UPI000C6F20AC -----------IFDRVGVNACVHVVDVDNGREV-GTRADEQVVLASVFKILLVLEFARQVV -AGQVDPTERVLVGAGDRLGGWGTAGCADDVELSLRDLAYFTMSVSDNTAADLLLRRV-GR -DVVPLLAAELGLARTRVIGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRDEAGPPAACG -MVRDLMSRQMF-WTRLPSGFPPEVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAQT -QRLSTRDVDLAMGEVAHAAV--- ->[subseq from] serine hydrolase n=1 Tax=Kocuria salsicia TaxID=664639 RepID=UPI0012EDAA72 --------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD -RGELDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH -ARVRDVLRELGLSSTVIRPGAPDAVPGYDPLLVSATTASDLVALLRAIWQDRAASAAQCA -FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS -VRRQIAVSNRIVGQIARHCVRSy ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces glauciniger TaxID=235986 RepID=A0A239M6A8_9ACTN ---------------------------GEAAEV-AVDADESVVLASVVKILPVLEFARQVA -AGQLDPRERVRIAAADRLGGWGTAGCADDVELSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVRLLAEELGLTGIRIVGGPRDVLEVLDPARTNAGTPREITRLLRLIWRDEAGPPQACA -WVRELMGRQVF-RHRMVSGFPDEVTVAAKTGTLP-GLHAEAGVVAHPDGGRYAVAVFART -REATRPAVDSAIGAATRISV--- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis albispora TaxID=1804986 RepID=A0A344LM32_9PSEU ---------------AGVRGWLHARRLGAEAEC-GWDADEPVVLASVVKVPLVLEFARQVA -AGQLDPRDRVRIGARDRLGGTGTAGCADDVELSLRDAAYFAMTVSDNTAADVLCDRV-GL -DNVRSLVRELGLVRTRIAGAPRDIVAALDPGWTNASTPREMTALLEHLWSEP---GEAAA -RVRQWMGQQVF-WSRLGGAFGPEVRVSGKTGTLPC-IRNEIGVVEYPDGTRFAVAVFTRS -ASQRQPAIEQAIGAAAAAAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=A0A4R2QWX1_9PSEU ---RLTRELNAHASTGDGQWHFSVWE--HGSPVvSLNGAVPVTAASTIKVPLLVVALQDVA -AGRRSLNDEVAIPV-ERVGGAGVLRLLPSVTLSLAEALTLMIVVSDNVATNAVIDLF-GV -ADTDQRITTLGLRGTRLRRRLMDQDAA-MAGLENVTTADDQAALLDRLAGAELLPDRLRE -FALDALGEQQV-NDRMPVRLAEDVRCLHKTGELH-GVRHDVGLLVFDDRM-VSLAALGTG -LTSP------------------- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. NEAU-THZ 27 TaxID=2575441 RepID=A0A4U3LZ67_9ACTN -----NARIRAVFEDAGVRGWLHAVALDEPESTvEVDADGIVPLASVYKLPLLAGFCRLVD -LGEIDPREQLTLDPSTKTGGPTGLSTFADPVASLRDLALSMMTLSDNASADALLDVV-GL -RRLAELLESFGLHRTRVRRGTADLQRVYEAANASASSARDLTLLLRRLWAGELLSPEQTE -FVKVTMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGTAYAIAVFTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] serine hydrolase n=1 Tax=Veillonella sp. VA142 TaxID=741834 RepID=UPI000F8D9020 ----------------------------HNESI--VKQSKPVRAASMIKVYILGYLFEEIE -AGHIDLGETIELEESDKVGGAGILSGAVGTKLTVDELAKLMITVSDNSATNILIHRL-GM -GSINQYVLKNGFIDTKLQRYMMDLE-AIRQGRENYTSAKDLGNWFMNLLEGKGMSNSSRE -KMLMYLLGQTD-TETFNEALS-NRLIAHKTGELA-GVYHDGGIIFQSKGEAYILITLSD- ------------------------ ->[subseq from] Putative beta-lactamase-like protein n=1 Tax=Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 12270 / PB) TaxID=1089553 RepID=K4LID4_THEPS ---ELRKELADHLKTLPGTYGVYFKDLASGEEF-GINERVPIPPASAIKLPVVLYLYEQVA -KGELDWNDRVRYRKSDYQDGAGDLQFTARDGYSLRCLATISMVISDNIAHNMLVRHL-GY -DNVMNFIRRLGPDTTRPF------GSA-------STTARDMGAFLEELIDFASREPEQGA -RLLNDLAHTVY-HVGLPGKLPPKLVVSHKEGSIN-GVATDVGIVFS--RRPYILVVLSKG -IP-DEDTGFRNIAEISRIVYNY- ->[subseq from] serine hydrolase n=1 Tax=Microbacterium sp. K27 TaxID=2305445 RepID=UPI00109BE9E8 --------------------------VADGPEV-TVGADDPVVLASVFKILVLTAYVRAVA -AGELDPTARTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDVIYHRL-GT -EAVDRVIADLGLADTRLIGCCEDLFAAVQPLRTSHSTPRDVTTLLNALWTDTAAAAEACR -QARDIMALQIW-PHRLTAGFPGEVRIAAKTGTLPT-WRNEAGVVTYPDGRRYAVAVFTRA -ASL-ADRQPLVDASIGRAAF--- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. Root322 TaxID=1736514 RepID=A0A0Q6PD28_9MICO ----------------------------VGPEV-TFGADEPVVLASVFKILVLTAFVRAVA -AGELDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMSMSDNAATDIIYHRL-GG -EAVNRVITDLGLRSTRLIGCCEDLFAVVQPLRTSHSTPRDVTTLLNALWTDTAAPAEACR -QARDIMALQIW-PHRLTAAFPGDVRIAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTQA -ASLV-DRQPLVDASIGRAA---- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B8ACE0 ---TTDEQLRAVFADAGCRGWVRAERIDTGTAV-DYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSFADPVTMSWRDIARSMITVSDNAAADAFLGAV-GL -DALTRVIDDLELEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRAIWLGTAASPAQCG -YMKEVLSQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. NEAU-D10 TaxID=2293571 RepID=A0A371Q7S3_9ACTN ----AEARIREAFDAAGVEGFFFAREIDGARTI-GVAADEPVCLASVFKIPIALAYAREAA -AGRLGRTERHAVDPRYRDGGIGTSGCTDPIEMSLRDLVHMMMTLSDNAATDVVLARV-GL -DTVNAMLAELGRNKTHLTGGCLDLIGVCVPERTTRGTARDTAELLAGIWRDEAGPAEACA -EVRTVMSQQIW-PHRLASGFDDSYRLAGKTGTLP-GWRNEVGVIEDPDGGRWAVAVFTRC -DRPDNPRADRVIGQVAALAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Agromyces sp. OV568 TaxID=2135465 RepID=A0A3E0I6F7_9MICO ---ALLRDAAEVLRSAGLRASIVVRDLGSGREL-SIAGDDDYPLASVVKLPLALAVLQRID -EGRLDPARPVTLRPDDRTPLVGYCRFQHPTTVSVEDLLYMAVCLSDDTAADALFDLC-AP -AAVTASLRETGITGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRSPALAP-QRD -RLRGLLAINVM-RQRLAPDLEDDAVWHSKTGTFLH-LRHEIGVLEHADGRAIAIAVLSES -SVQRQPAAEQALGLAAKLL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ag82_O1-15 TaxID=1938855 RepID=A0A2A3J362_9ACTN ---------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS -HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART -REATRPRVDAAIGAAAAMAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. CUA-806 TaxID=1517936 RepID=A0A1Q9U2V8_9NOCA -----EDQIVEVFHDAGCRGWLHAQRIDAGPTV-DVNGHEPVVAASVYKVVVLVAAARAFD -SGRLDSHTQVRVVPSDCTPGPTGISTFTDPVLSWLDLVRSMITVSDNAAADILLAAL-GF -GIVEQVIVDFGLSSTRIVGGTAALQGAYDPAYTTATSAADTNSLLSAIWEGRAASPQMTN -HMKTMLSQQIW-PHRIRSGFPADVTIAGKTGTIGS-VRNEVAVVAFPDEPPIAVSVFTRA -ARSDLPLVDQAIGRVARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Marinisporobacter balticus TaxID=2018667 RepID=A0A4R2KC45_9CLOT --kNLKDKIKNILNAIDGNKGLYMKDCSTNEIL-TINENRRFHAASTIKIAILYEALLQVQ -SKKRKLDDLYKLKSSDLIGGCGVLKLHVGLAVTLEDLITLMITVSDNVATNILHDIL-GK -DNINDSIQTLNIGNTFFARKLMIPDSN----LYSYTTAKDLGILLNEFLGCKKLNEDIAN -KGLEILYKQQY-NDRISD------------------------------------------ ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Halococcus agarilyticus TaxID=1232219 RepID=UPI0009AC2516 ----FDELIDEYRDRIEGRLGIFLGRPKPNDIVyTVRPDERFTSASMIKVPVLWTLYDCYD -GCLDDLTTPNGIAEANRVDGSGVFHLLADLNPSLEDLARAMIAISDNTATNELIDHL-GC -ETVTERMHELGLTETRLGRKMMVTDELPPDALENLISPRDVAMLFADIHRGETLSRRAYE -RLRVPLRHQKD-TSMFARYRPLDHRMEHKTGWLST-AALDAGVCHAGND-PLVYAVFLDG -MDH-GGDGTDVIAEIGDAVH--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00036752AE ------------LDRIPGTVSAYLARLDARPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARRSSTGRGIEDFAAR-TAGITNLVTAADLAALLRDLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCHTG -DHPDRSADTQLLADVSAHA---- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus polygoni TaxID=1235259 RepID=UPI0011F1E530 ---------------------------SSEGSI-GINANTPRKAASIVKLFILAEVLQQIE -AGSVQKEQLISIQPEEMVEGAGVINYLTNHDYSYQNLVELMIIVSDNTASNILLDTI-GI -ERLNYSIKKLGCQHTTINRKFMDHQAQ-ANGDENMTTATDVAYLLKLFSNENGYSSSIRR -EVRRILKNQQF-NHKLSAFQMDKLKIYHKTGELP-GVEHDAAIMESNGK-KLEVAVLTEG -WEN-NGIAHHFMGEVGRYLMN-- ->[subseq from] UPI0013E905DD UniRef100 entry n=1 Tax=unknown TaxID=N/A RepID=UPI0013E905DD --------IKKYLETREGNYSFYFEEINSGYLY-GLNENKEMVSAGCIKLPLAMSLLKEVQ -NGKIDLQSKIKIKSGDKIHSNGIIHEFSGKEYSIFDLLIAMLIQSDNTAANKIIEVL-GM -QRIDELFKDMGLKNTKLKRITTDIKLE-QEELENTTSSFDLSKCFKLLYLKQYLNEENSD -LLIRILKKQQV-TNKLPFYAPKQIQIANKGGSLET-VENDTTLMMIEKGN-FLFTVMANN -LP-NNVYGITTISRVGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI00097859E5 ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] Beta-lactamase n=1 Tax=Natronorubrum tibetense GA33 TaxID=1114856 RepID=L9VNY0_9EURY ---ELRSTAEQIDEGLDGRLGVVVCDVGNGEPLlSIRSRDRFGAASIVKLPILYALYRTYD -GRLEALDRPHQIAPENRVGGSGLFHLLADPTPTVEDLATAMISVSDNAATNELIDHL-GF -DDIAAAAADLGLEGTHLGRKMMQTPASNGHRYVNWVTPLDCVVLLSDIHRERTLSSAAYE -QLSRPLAHQHD-GSMVPRYLPPDAEIRHKTGNLPS-VAADTGLLTVDGR-TVAYAICCDG -LER-RGEGVDAIAKLGAGVY--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. Ade.TY TaxID=1391647 RepID=UPI00041C3230 ------KEIKKYLESRIGTYSFFFEDLESGFVY-GYNENVKITAAGCMKLPIAVSLIKDVE -RGKITFMDKIKIDGVDKVYGTGIIHEFNSRDYTVFELLVAMLIQSDNTAANKIIDIV-GM -DRINEDIKEMGLENTKLNRKTADERRD-NINVENLTSARDLSKIWKHLYKATYLNEENST -MLIDILRRQQI-KNKLALYIPDNYEISSKTGDKT-GVENDTALIQLSKGT-FTFTVLSTE -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Secreted beta-lactamase n=1 Tax=Streptomyces sp. W007 TaxID=1055352 RepID=H0B9D5_9ACTN ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMARQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -RQASRTAVDSAIGATARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Jiangella muralis TaxID=702383 RepID=UPI0009FB5B64 -------------------GFLHAVDVGPGAEV-GVEPDAPVVTASVFKIPVLVELCRQFA -TGERSAADRLRVPAGGRTLGPTGLSVMLDDALSLRDVAYLMMCVSDNHATDALMALL-GR -EKINAGTAALGLPATVLEEDCAGLFRVLDAETTNRSTPRETTTLLRRVWTTDGLPEAACD -EIRRILGLQVW-PHRLTSGFPDDVKVSGKTGTLSH-VRNEVGVVEYPDGGTYAVAVFLRL -PGAENPAADAVIGTAARIAVDH- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Marinimicrobia bacterium TaxID=2026760 RepID=A0A2E1J157_9BACT -----HEEIKSLISSFNGEVGFYFSHLEKGIQF-GINENKIFPTASLIKIPIMVQIFNRIE -NDNLNIDSLLIYDSSLIDYDDSIARFKEKETISINKLLTHMITFSDNHASLWLQNIAGGG -AKINNLLKENNFNKTRINSRTINREDQYLKYGWGQTTSKEMSELLIKIRDGDLISKKSSN -NMYRHLTRIYW-DDEALSQIPNHIQVASKQGAINK-SRSEVVLVNAPNGD-YVFCIITNN -QFDEENEGFALIRKISKILWNNf ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Gordonia terrae TaxID=2055 RepID=A0A4U9Y2S3_9ACTN -------------------------------EY-CHDADTPVVLASVYKLAVLISLCRIAD -RGDIDLSASVTVDPTRWAQGPTGLALFVDPVLSWRDLATSMMTASDNVAADVILAQI-GL -QQVRDDLVELGLTNTRIVGGVAELHEAYDAAYSSSATPRDCTTLLDAVWTDRAASASSCE -FVRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEVGVVEFPGELPLAIAVFTMS -ARSELPEVDRAIGLVARAVVT-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Synechococcus spongiarum SP3 TaxID=1604020 RepID=A0A0G2HMX8_9SYNE ----LEERFQALAASQDLLAGAYVAVLGDGQHA-RLNSDRATAAASAIKTPLLLLTLLARS -QGELRWDETLQLQPHLVGGGSGWMGSEPPGSFPLYMAAREMITVSDNTATNLLMERLGGM -EAVNRRFLALRLRGTRVNNWLPDLGGT------NTTTPRDLALTLAMAENSALLSQQDRD -RFRAIHGSSRP-NSLLPLGFLQGVRILNKTGDIGT-AYADAGTIELPDGRRAVAAFLVEG -TEYNSPRMRRLIQNMAAAT---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 844.5 TaxID=2485140 RepID=A0A3N1L6Q3_9ACTN ---TAQKNIRAAFEEAGVEGFLFARDIDGSRTI-GVAPDELVCLASVFKIPVALGYAREAA -AGRLERTERHSVEQRYRDGGIGTSGCADPVEMSLRDLVHMMLTMSDNAATDVVLERV-GL -DTVNALLAELGRNRTHLIGGCLELTGC-VPERTTRSTARDTAELLAQIWRDEAGPAEACA -EVRTVMSHQIW-PHRLSSAFDDSYRVSAKTGTLP-GWRNEAGVVEDTDGGRFAVAVFTRA -RIADNPAADRVIGTAARLAVDE- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces qinglanensis TaxID=943816 RepID=A0A1E7K3P7_9ACTN ---------------AGVRGWLHVAELHRAARV-TVDADGLALMGSVYKLPLMVAYCRQVD -AGALDPRQRLTLPAGDRLPGPTGLSLLRDEVMSLRDLVVMMMSISDNAAADAVLRQV-GT -AAVEETCAALGLHRTRLDGGAAGSLAVYDPAWAAATTPAELAVLLRAVWLDEAASPGSCA -FMRATLGLQPW-QHRLAAGFPDEVAVYGKTGTFG-AMRHEAGVVELADGRGYTAVVFTQA -ARADLPRADAVIGAAARTAVEH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0006DA215E ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb43 TaxID=1848688 RepID=A0A2S8UTT7_9MICO ----IGQDIAEIFADAGATGFLHARQIGDGPEV-NAGANEPVVLASVFKILVLTAFVRAVA -AGDLDPTERTTVTARYRIGGVGTAGFADDVEASWRDLALNMMTMSDNAATDVIYHRL-GA -DAVNRVVSDLGLQKTRLIGCCEDLFAVVHPLKTSHSTPRDVATLLNALWTDTAAPAEACR -QARDTMALQIW-PHRLTSGFPGEVSLAAKTGTLPT-WRNEAGVVTYPDGRQYAVAVFTRA -GSL-ADRQPLVDASIGRAAF--- ->[subseq from] DNA-binding transcriptional LysR family regulator n=1 Tax=Ponticoccus gilvus TaxID=519423 RepID=A0A4R6LW60_9ACTN -----VAQIRDVWRAVGVVGGLHARDLRSGAML-AVDADDAWPMASVAKVPLGIALHRAAD -AGLLGLDQALTLRPDGRTSGTTGISAMADPVLSLRDALYLALTISDNAAADAIWDTL-GA -DRVQHLLRQLPPDQVRLGEATRDLYDSLDGPYACRATAAGATRMLELIWSDQAASPAACA -AIRDLMRRQVW-AHRLASGFPADLEVAGKTGTAGD-HRHEIGVVSYPDGRRFAVAVFTRL -QQETPHHRDWAIGETARLAVN-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048BB48B -------------DRTPGTVSASLGHLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGRLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGTLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. GLM-1 TaxID=2267691 RepID=A0A427TLY2_9PSEU -----------------VRGFLHVRRLGSPAST-GIGADSPVVLASVVKVPLAYEFARQVA -AGLLDPADRVRATAADRLGGTGSAGFEDDVSYSLRDAARLALSVSDNTAADLLFDRV-GV -ANVRSLLAELGLTRTSVIGAPRDLLRALDPLRTSATTPREMTALLAAIWADPA-----GE -PVREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG -GSETRPDIDRAIGDAARAAVEQ- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus damuensis TaxID=937928 RepID=UPI00082CC838 ----LESALLSLINDDRENFSIAVH-TDEG-NI-NINADKPRQSASLAKLFILAKVYEQVE -TGSLLLDKLVYIDSKKMVGGSGVISYLTNCHYSYQNLVELMTIVSDNTASNILLETI-GA -EQTNQFARKLGCSNTNLGRNFMDQVSR-MDGFENVTTACDVCNLLTHFSRENFFTENSRR -NIKKILGNQQF-NSKLSSYHQSTIKIYHKTGELQ-GVEHDAAIMEANGN-TMEVAVLTEG -WSN-NGMAQYYLAEIGRMLR--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000487F14A -------------DRMPSTVSTYLARLDATPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AGRLTPDTAVPVRNEFDSAQPGAAWDRLGGTAPLGWLAERMIVRSSNLATNLLLEQV-GL -PAVADVWARAGARHSSTGRGIEDFAA-HAAGITNPVTAADLAALLRDLALGALATPESCT -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTG -DHPDDEETCQLIADISARAF--- ->[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. KC13 TaxID=2711220 RepID=UPI0013EB882F -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPIAVHPDSAVTGSRFEWEAVGSALPLGDLVRRSLTVSGNLAVNLVLERV-GL -EEVAAVLADAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA -ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Beta-lactamase n=1 Tax=Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 / TK0059) TaxID=509190 RepID=D5VFF5_CAUST -----------IAARAPAVLGVAAEDLGTRQIW-GFNGDRAFVLGGAARVPVLAAVMAERA -AGRLDLNEQIDARDVDLSPPSAVADAWPGREYTVAEL-EALARTGDNTALDLLTKRIGGP -GAVNGWLDVRQLRGVSVDRYRRQVETQRAADPRDTTTPVGVVRLLETFNTREAFASADPR -LLLG----ND--PGYLASALPEGAKIWQAAGSARVAESHAVALIELKDGRRIALAVFLTR -STTDVAAREAIITEAGRTVLKSf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB01635 TaxID=2020326 RepID=A0A2M9JH14_9ACTN ---ELVETITGRAAEVGVQVRLHAADLDSPRQV-GIDADEPVVTASVFKVPVAVELARQAA -DGELDLAERITVPPGHPTAPYGLATFLHDVTMSWYDLAVLMIGISDNVATDLILGKV-GK -AAVAETLRRLGLPQTAVPHDCGDLLRALTPEETCRTTAAESTRLLGLIWRDEAAPAAACA -DVRRWLELQVW-PHRLRSGFADDVTISGKTGTLPS-LRNEIGVVEYPDGGRYAVGVFTRA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium saccharoperbutylacetonicum TaxID=36745 RepID=UPI0009838EBA -------EVKRYLESRIGTYAFFFEDLESGFSY-GYNENVQMTAAGCMKLPISVSVLKYVE -DGKIDFLDKIKIEEADKVYGTGILHEFDNREYTVFELLVAMLIQSDNTAANKLIDIV-GI -DRINDDIEAQGLKSTKLNRRTSDERAA-SNGIENITSALDLAKIWKHLFNSSFLNEKNSI -MLMDILRRQQM-KNKLALYIPDDYEISSKTGDKAN-VENDTALIHTHKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium beijerinckii TaxID=1520 RepID=A0A1S8P8Z1_CLOBE -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSIIKHVQ -EGNSTFLDKIKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIDIV-GI -DKINDDIEAQGLKNTKLNRKTSD-ERAVSNGIENITSALDLSKIWKHLYDSSFLDEKNSK -MLMDILQRQQM-KNKLALYIPDDYEISSKTGDKAS-VENDTALIHSPKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=2 Tax=Bacteroidetes TaxID=976 RepID=A0A257ITV9_9BACT ---KLQKIIEEATYGFNGVIGVYVENLKTGKFA-EVNADTIFPTASMIKIPIMIGTFSHIL -NGKLRYDQILTYKDSLKYDEGLVGSFRDSTKIPVSELIYLMESVSDNTASLWLQGLV-KG -QRINQLMDSLGMQNTRVNSRTPGRSAFQKTYGWGQTTPKEMASLMKMLRKGEIFTQDASY -RMYKTLGNQYWDG-EGLSQIPENTKTAYKSGAVDR-SKSEVMLVHAPHGD-YVFCMITKN -QTDKNNEGYRAARRISSSLWKYf ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium sp. 7_2_43FAA TaxID=457396 RepID=V9H2D7_9CLOT ------KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQMVAAGCMKLPIAVSLIKSVE -DKKIDFLDKIKIDGKDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM -EKINKDIKEMGLKNTVLNRKTTDER-KTKSEVENITCALDLARIWRHLYNSTYLNEENSQ -MLIDILTRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FTFTVLSMG -IPNS-VYGTVTLAKCGKTMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium UBA8153 TaxID=2060924 RepID=A0A3C0FBB5_9FIRM -------------ARTTGVIGFSILDLGEGKEY-SHLGDTVFPTASTIKIPILVALAHQVF -RGERAWDQRVPVPRA-RAGGSGMLQWLQHVELSVWDLASLMIAISDNVATNICIDMV-TM -EAVNRLLDDLGLSRVRLRRKMMDPEAV-ARGDENVATPTQLTRLMSKLHYQVEIPEPVCH -DVLAILRLPKQG--PFTEALPVEVPRANKPGGLP-GASIDSGIVYLPRR-PYALTVMGTF -LEED------------------- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535XMR4_9CHLR ---ELVQQLDGLISSFPGGAGIWIADPTVATPLfAHDPDEQVIAASLYKLGVLAEAERRVD -TGDLHYNDAITIQPEDITLDGSF--EDAGTQLTLDEALEAMITISDNGSALALWRIL-GG -SNIDATLEKAGIKNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISGAASD -RMLARLERQQI-NDRLPAQLPPGVVVAHKTGNLTS-VTHDAGIIFTKTGPRVVVAMTWDA -PD---EDAANFISSIGSLVYS-- ->[subseq from] Beta-lactamase class A n=2 Tax=Hungateiclostridium clariflavum TaxID=288965 RepID=G8LTV1_HUNCD --kDLLSSINDVIKNETDIVRVSVYDFATGTTV-SYNGQERFYPASLSKIVNLLCFFEEVQ -KGNFSLSSVYTLKQSDKYIGTGNLQYQANGTYTYEDILSRMISLSDNVASNIIFDAL-GR -ERLDAFCEMYGLKDTRIYKKFYDGDKNFP---SNYSTADDLTRMLVLLENRLSVEDNLSI -LGIEYMKETVN-KDRIALYAPEDVVIANKVGFISR-LSGDMALVYFPDREPIALTIVVED -DNINQEKANELIGTLSREIIDYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. CB01201 TaxID=2020324 RepID=A0A2M9JB92_9ACTN --------ITAALTDAGLGGALCATDIDTGATV-ALAADTPVSTASVHKLCLVATLYREAA -AGRLDPTTPVDIPAGARAPPTGLAVMRDAARLSLRDLASLAVAVSDNAAADVLWDHL-GL -DTVNATMNALGLTRTVAVHNQAGLYAVLDPARTNRSTPREIAALLTAIWRDEVCAGAWGE -ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA -ASATLPAADAAIGRAARVAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG08_land_8_20_14_0_20_39_18 TaxID=1974883 RepID=A0A2M6XDE6_9BACT ---EIIKQVNNLTANLTGDYGLYVFNLTTKISF-GISENQVFKAASLMKLPLILTLYKNVE -AGKIDLQTKYTLKAADKRPGAGSMYYKPAGTYTYQKMVELMGQQSDNTAFNVFRNLL-GD -EQIQKTIDDLGMTKTNFTDFE--------------TAPAEIGLFFRKFYSGSILTRAHRD -EILGYITKIFD-ESRIPAGIPAGVRVTHKVGTDT-GVASDGGIVFG--TKPYIIVIMSDK -NLK--VEADAVLPKISSAVWE-- ->[subseq from] Serine hydrolase n=1 Tax=Microbacterium sp. MYb72 TaxID=1848693 RepID=A0A2S9AFS1_9MICO ---AVEADIARIFADAGARGFLHAREIGGGPEV-GVGSDDPVALASVFKILVLTAFVRDVA -AGALDQTARTTVTARYRIGGVGTAGFADDVEASWRDLALLMMTMSDNAATDVIYHRL-GG -DAVDRVISDLGLDRTALIGCCEDLFAALDPPRTSHSTPRDVTRLLTALWTDAAAPASACE -QARTIMAQQIW-PHRLSSGFPNGVQIAAKTGTLPR-WRNEAGVVTYPDGRQFAVAVFTLA -DTL-ADRQPLVDASIGRAAL--- ->[subseq from] Beta-lactamase class A n=1 Tax=Haladaptatus litoreus TaxID=553468 RepID=A0A1N7B1H7_9EURY ---ELGEYIERYADRIDGELGVFLYGPDEFDTVcARNARRAFRSASVVKIPILYALYERYD -GRLDSLAESCPLSPENRVGGSGILH-LLDATPTIEDLARAMIATSDNAATNQLIDLL-SM -TTVNDSAAKLGMKHTRLARKMMTTLEVPENEPANVTSPVDCARFFADIACEATLSANAYE -RMRVPLSAQKD-TSMVPRYLPYETEIMHKTGWLPT-AALDAGLLSVPEKPPLVFSVFVDS -VSN-GADAADAIAEIGDAVF--- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. 05-2254-4 TaxID=2022492 RepID=A0A260MNB7_9NOCA ---TTDEQLRAVFADAGCRGWVRAERVDGTGTVvDFEGDDPVVAASVWKIVLLVATARAFD -EGVLAATGSVRLVPAQCSPPTGIASYADPVTMSWRDVARSMITVSDNAAADALLGAL-GL -DALSQVIDSLGLEDTRIVGGTKTLGDGFDPAYTSCTTPRDSNAVLRAIWLGTAASPEQCR -YMKGVLSQQVW-PHRIRSGIPPDVEVAGKTGTIGP-IRNEVAVVSFPGEVPVAVSVFTRA -ARMDLPLVDQAIGHAARVAV--- ->[subseq from] hypothetical protein n=1 Tax=Caldanaerobius polysaccharolyticus TaxID=44256 RepID=UPI0006896E56 --qPLKQKIAEYISSNNLSAGVYFKDLTTNTDF-GINENKAFTAASTVKVPIVLYLYTLAS -EKKVDLNAKIAYDKDDFESGAGVLEYKPGDKYSLRTLANQAITTSDNIANRMIMRYL-GK -DNIIKFMKNLGGKTV------------YPG-GKNMTTAKDMVTYMEAVISFTKANSELGK -MLLDDLAHTVY-NSGIPALLPDGLYIPHKEGDLHD-VANDVGIVYCQ--RPYILAVLTDK -NK-DVETGFKHIARISKMIYDY- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. CB00013 TaxID=1703945 RepID=UPI00093F8EE6 ---QVTETITERAKEVGVRVRLHAAEIDGTRRI-GVDEHTPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -EATEKTLRDLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA -DVRRWMDLQVW-PHRLRSGFPDGIRVGGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 1-11 TaxID=2590549 RepID=A0A510TUM8_9ACTN -----EETIVEVFAAGGCRGSLSVREIDGPRRL-SVAGGELAVAASTFKIAIGLEFFCRAA -EGDVDPAERVAVSPAEASPGQGLCITEDPVEISLRDTARLMLTISDNTATDVLIRRV-GI -ERVRARLAGLGLTGFHLPRYELDTAAGMRPGRISSVTADDLAALLRAVWRDEAGPAQACS -DLRRMMGQQRL-TRKIAAGFGPHVQVVSKSGTVPGGVSNDAGVVAFPDGRRYAIAVLTRP -LTPGAPTREDILGTAARVALDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium cavendishii DSM 21758 TaxID=1121302 RepID=A0A1M6RZQ3_9CLOT -------EIKKYLETRIGSYSFFFEDLKSGFIY-GYNENVPMVAAGCMKLPIAIALIKNEE -EGKINFLDKVKIEGKDKVYGTGIIHEFDEREYTIFELLVAMLIQSDNTAANKIIDIV-SI -ERINEIIKEMGLTNTVLNRKTTDER-NVKPEVENLTSASDLARIWRHLYKTTYLNEKNST -MLIDILSRQQI-KNKLALYIPDDYDISSKTGDKQ-GVENDTALIHLHKGN-FTFSVMSTG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase n=1 Tax=Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) TaxID=521096 RepID=D5UMR9_TSUPD ---ATAAAIAEVFADAGCNGWLHARVVGADAEL-SVSGHEPVVPASVYKIVLLVAACRAFD -SGRLDPRQRVTVDPRTATPPTGIATFDDPVQLSVRDLARSMIAVSDNAAAGTLLSLV-GL -DEVQRTARELGLRRTVIAGGDAEMHTAYDPSFGSATTAADATALLAAIWSDTAASPQGCA -FARSALAGQVF-RHRIASGFGPGAEIAGKTGTLG-ALRNEAAVVSYPGEHPVAVAVFTHA -ARND-PALPRVDAAIGRVAL--- ->[subseq from] PEGA domain-containing protein n=1 Tax=Candidatus Dormibacteraeota bacterium TaxID=2052315 RepID=A0A2W5YD62_9BACT ------TELQAYLTATGGTFGVYLEQLSSGRTL-AIDQDASMEAASVIKIPVALYLLSQVD -AGQVKLSDKVKLEAKDFMGGTGILYGSAKAGIPYQDLLADLVRQSDNTAWQALQRVL-DP -AKIDGFAAAQGAPD---------CHQ-----LSDQCTARQAGQLLSKLGRGGLLSGDSTD -RLIQLLETTVF-NDRINYYLS-GVSIAHKIGIDGN-VINDCGIVYAATGA-FTICVFTRT -AD--QPTGIQAIRDIARAAYRY- ->[subseq from] Beta-lactamase TEM n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=A0A173YT49_CLOVE ------KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE -EGNIDYLQKIRVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDMV-SM -DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ -MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD -IPNS-VYGTITLAKTGKMIWD-- ->[subseq from] serine hydrolase n=1 Tax=Kocuria salsicia TaxID=664639 RepID=UPI0011A0ED85 --------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD -RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH -ARVRDVLREMGLSSTVVRPGPAPDPVGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA -FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS -VRRQIAVSNRIVGQIARHCVRSy ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sartagoforme AAU1 TaxID=1202534 RepID=R9BUA5_9CLOT ------KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQMVAAGCMKLPIAVSLIKAVE -DKKIDFLDKIRIDGKDKVFGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM -DKINKNIEEMGLKNTVLNRKTTDER-KVKNEVENITCALDLAKVWRHLYNSTYLSKENSQ -MLIDILTRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FTFTLLSMG -IPN-SVYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A2Z5JQJ3_STRAR ------NRIRTAFDDAEVQGYFFAREVDGDRTI-GVAADEPVCLASVFKIPIALAYAREAA -AGRLDRTERHSVDPHYRDGGIGTSGCADPVEMSLRDLVHMMLTMSDNAATDVVLARV-GL -DTVNGLLAELGLRKTHLIGGCLELTGVCVPERTTRGTARDIAELLVRIWRDEAGPAEACA -EVRAVMSQQIW-PHRLWSGFDDSYRVAGKTGTLP-GWRNEAGVIEDRDGGRWAVAVFTRS -DRPDNSRADRVIGQVAALAVDE- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. TSRI0395 TaxID=1703923 RepID=A0A1Q5BZE4_9ACTN ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Roizmanbacteria bacterium CG11_big_fil_rev_8_21_14_0_20_36_8 TaxID=1974856 RepID=A0A2M6IU44_9BACT --------------NKKDKYAVAVKNLETGESL-YINEDKEFLTASLYKIWVMAVVFQKIE -EGSLSIDDNLKQDVTILNKKFNIATEDLQSGFTVREALNKMITVSDNYAALLLNEKI-GV -VSLSKFLLDFGFDQSQISQP-------------PVTTAHDMNLFFEKLYRGEFANEQYTN -DMIELLLAQEL-NDSIPKYITDKVKIAHKTGHLYT-VTHDAGIVYTANGD-YIITIMSEG -EN--EPDAKEMMAKISERVYEYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 42 TaxID=1827576 RepID=A0A495CJI2_9ACTN -----------------------IWPPGEAREV-AVGADEPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS -HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART -REATRPRVDAAIGAAAAMA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces mirabilis TaxID=68239 RepID=A0A1I2MKE4_9ACTN ---------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLERV-GL -DTVRLLAKELGLDRTRIVGGPRGVLDVLDPLRTNASTPRETCELLRLIWRDEAGAPEACS -HVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFVRT -REATRPTVDAAIGAAAGIAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Aureimonas sp. AU20 TaxID=1349819 RepID=A0A0S2EUT0_9RHIZ -----------LGDETCGRLSLFAKDLSTGRTI-EADADRVMGTASCIKLFILIELLRRVS -AGDLALGDRIAVDAAQQVGGSGILKALSAGLMTLRDAAVLMMALSDNTATNMLIDLL-GL -ERINRTATELGCAHTRLINRIDF--EAIDGDITSVGTTRDFALALERIASGALFDEAASA -VALDILSCQLH-VDLLPRYLSQDLWVANKTGFFP-GFRGDVAIFTLPDRR-IVAAAFLDD -IEAPENPGARRLGEVGAALLA-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. EC080619-01 TaxID=1096856 RepID=A0A0P0SBF5_9PSEU -------------------------------EV-AVGADVPVVMASVYKLLVLVGYCRAVD -EGRLDPREPVVVPPGRTPGATGISALADPVTMSRRDLVTSMITVSDNVAADVVHAAV-GR -DRVAALPAELGLTGTRIRGGTADVLAALSPVFGSSTTAADATALLARLWRGELASDAGTA -FARQVLSAQIW-PHRLRAGFPASAAVAGKTGTVG-AVRNEVGVVTYPGEHPVAVAVFTHA -ARSDVPRADAAIGAAARTAVN-- ->[subseq from] Beta-lactamase CARB-6 n=2 Tax=Clostridium thermobutyricum TaxID=29372 RepID=A0A1V4SYK4_9CLOT -------EIKKYLESRIGMYSFYFEDLSSGFTY-GYNENVQMVSAGCMKLPIAVSLIKDVE -DGNVTFLDKVNIDVDDKVYGTGIIHEFNSRDYTIFELLVAMLIQSDNTAANKIIDIV-GI -DKINKDIKEMGLKNTVLNRKTADERS--KVEIENFTSSKDLGIIWKHLYNGTFLNEKNST -MLIDILRRQQI-KNKLALYIPDDYEISSKTGDKK-GVENDTALIQLSKGN-FVFTVLSQD -IPN-SVYGTVTLAKCGKMAWD-- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus mycoides TaxID=1405 RepID=J8HYF7_BACMY ------------------------------------------------------------- --------------------------------MTLGEIAEAAIRYSDNTAGNTLFKKLDGP -KGFEKELGQNGNKVTLADCFEPDMKEAIQGDICDTSTVKTFAINLKAFTVRDALQTDKRK -IPTDWMRGNATGDELIHAGVPKDWEVDDKSGAGSYGTPNDIAIV---------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Nocardia pseudovaccinii TaxID=189540 RepID=UPI0009FC5924 ---------EEIFRKAGVRGWVHARCFDCAGAV-GLGADEPVVLASVVKVPLVLEFARQVV -AGQLDPTDRVRASAADRLGGVGTAGCLDDVEFSLRDAAFFALTVSDNTAADLLFDRV-GL -DNVRSLVRELGLTETRIVGSPRYVVQAMDPLRTTASTPRDMTRLLTLLGQDLAGDPAACR -WVRQLMGQQLN-WHRLAAAFPSEVSVWGKTGSLP-AIRNEIGVVAYPGGSRYAVAVFTRA -DTQRLPEVDHAIGAAARLAIH-- ->[subseq from] serine hydrolase n=1 Tax=Gordonia sp. IITR100 TaxID=1314686 RepID=UPI000991442F -------------------------------EY-CHDADTPVVLASVYKLAVLVSLCRMAD -RGDIDLTASITIDPTRWAQGPTGLALFSDPVVSWRDLATSMMTVSDNVAADVILAHI-GL -PQIHDDLVDLGLTHTRIVGGVAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASAASCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEIGVIEFPGEVPIAVAVFTMS -ARSELPEVDRAIGEVARVIVT-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. KNN50.9b TaxID=2018303 RepID=A0A229TJA9_9PSEU -------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVTAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEISVAEYPDGARYAVAVFTRA -PTSRLPDVDHAVGAAARAAIE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A5P2XJY1_STRST -----EERVREVFARAGAEGALHAMDAPGGDDV-SVAADTPVAISSVFKVLLVLEFARQAA -AGQLDPRERVLVTDAHRLGGWGTAGCVDDVEISLRDLAYFALTVSDNSAADILLSRV-GL -DTVGMLARELGLTRTRIVGGPREALAVLDPRRANAGTPREVTRLLDLIWRDAAGPPEACA -RVRELMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS -RAADLTRVDAAIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis thermalba TaxID=944492 RepID=UPI000E265553 -------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVTAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEISVAEYPDGARYAVAVFTRA -PTSRLPDVDHAVGAAARAAIE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. Ae707_Ps1 TaxID=1885572 RepID=A0A1Q8KIE1_9PSEU -------------------------------EV-AVGADVPVVMASVYKLLVLVGYCRAVD -EGRLDPREPVVVPPGRTPGATGISALADPVTMSRRDLVTSMITVSDNAAADVVHAAV-GR -DRVAALPAELGLTGTRIRGGTADVLAALSPVFGSSTTAADATALLARLWRGELASDAGTA -FARQVLSAQIW-PHRLRAGFPATAAVAGKTGTVG-AVRNEVGVVTYPGEHPVAVAVFTHA -ARSDVPRADAAIGAAARTAVN-- ->[subseq from] Uncharacterized protein n=1 Tax=bacterium TaxID=1869227 RepID=A0A3A0FMU4_9BACT ----------DELGADVGRFGVVARRLDDGLGA-GVNPDRVFYAASTFKLALLYEAELRRS -QGLLDFNAPLPLDESDLSEDLGTFENLPEDGLTIGAALEAMITLSDNASAVALLRLL-GP -EAIDATLATLGLKHTSVNTREL--P----------TTASDMALLMEAIVRGEGVDPEARG -HMRSLLLAQHS-RDGIPAGLPGSARVGNKTGTWEQ-ATHDVAFVETTSGT-YVVAVLSDS -DR-----DWGRIARVSGA----- ->[subseq from] Serine hydrolase n=1 Tax=Acidipila dinghuensis TaxID=1560006 RepID=A0A4V1NVE2_9BACT ----LEAALHAAIASHNGHVAVFAEDLATGRTV-AIDADTPVQTASVIKLAILYTALEEIR -DGKAHFEDKLTLKHSDQVAGSGVLTFFDTPVLTLKDALTMMIIMSDNTATNLAIDHL-GL -KNIDDQILALGLKNTWLYKKVFLPADDQKQFGLGKTTAREMASLFERFVTNTAATADDHA -LCNAHMLSNQFYRDSIPRYLEAQSEIANKTGALD-AVRNDVGVVFTKAG-PVVISMFTWG -NKDTDNQAEVLMAKLAKQIVGTw ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter segnis TaxID=88688 RepID=A0A2W5V4X7_9CAUL ---ALQKAMEPIAARAPAVLGVAAEDLGTRQLW-GFNGDRSFVLGAAARVPILAAVAAEHA -AGHLDLGETIAVRDVDLSPPSRIADDWPARQYTVRELQDLA-RAGDNTALDLLTKRIGGP -GAVNGWLDVRQLAGISVDRYRRQIKTRHEADPRDTATPVGMVRLLETFNTREVFASADPR -PLLG---GD---PGYLAAVLPEGASIWQAAGSARVAESHAVALIALKDGRRIALAVFLTR -SPAEARAREAIIAEAGRTVMKSf ->[subseq from] serine hydrolase n=1 Tax=Nocardia anaemiae TaxID=263910 RepID=UPI0007A395E8 ----------EIFGKAGVRGWVHARCFDCTGEV-GLGSDEPVVLASVVKVPLVLEFARQVV -AGQLDPTDRVRATAADRLGGVGTAGCLDDVEFSLRDAAFFALTVSDNTAADLLFDRV-GL -DNVRSLVRELGLTETRIVGSPRHVLQAMDPLRTSASTPRDMTRLLTLLGQDRAGDPAACR -WVRELMGQQLN-WHRLAAAFPPEVSVWGKTGSLP-AIRNEIGLVAYPGGSRYAVAVFTRA -DTQRLPEVDHAIGAAARSAI--- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. MJM2582 TaxID=1427749 RepID=UPI000502EEAD ---QVTERINERAKEVGVRVRLHAAEIDGSRRI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILERV-GK -EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA -DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Saccharopolyspora sp. 16K404 TaxID=2530385 RepID=A0A4R4UHP4_9PSEU --------------ELPGRAGIASWDLRENAPV-LRGAEVEVHSASTIKVLVMITALRAVA -DGRLDLDAQVELPAE-RTRGTGVLFEVPSVPASLRDLINLMIVVSDNAATNAVIDQV-GF -TAIAECTADLGCTSTRIERHIMDTGA--PGV--LQTTALDQARVLAALAEGVALPPQLTR -HALTVLSRQQV-VDRIPLLLPENARCWNKTGEIK-GLRHDVALLSTDDTPQVVLAVLVDQ -LTD-------------------- ->[subseq from] serine hydrolase n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=UPI0006DCAE1B ------KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE -EGNIDYLQKIRVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDMV-SM -DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ -MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD -IPNS-VYGTITLAKTGKMIWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. b84 TaxID=1827631 RepID=UPI000BEF37CD ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMGRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -RQASRTAVDSAIGATARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000BEFC845 ------------------------------GEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMGRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -RQASRTAVDSAIGATARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Gammaproteobacteria bacterium TaxID=1913989 RepID=A0A432F057_9GAMM ---TLENELNQLCDEQPFHTGWYVKNLRTGAVL-ERHGNAVVPSASTRKIAIMMAALKAVN -EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL -ELINVLCQSIGMVDTVHRYGIPGMAGYLPADKTNSTTPADVALLLEIILQGVVCTPDLCQ -LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYAGDRPLFLISAYTDN -VPAEHTVAYDLTARLSRLCWDE- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A348Z7C3_CLOSP ------KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVE -STNIFLDQLVTITNDDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK -DRINSIIHDMGLTSTFIKKYPSGEKED--FDNENITTSYDLCKGLALLSKGKVLNGEHSK -FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLE-GIENDIVLLNLEKGD-FVFVVMSRN -LPS-NVYGVS------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Caldanaerobius fijiensis DSM 17918 TaxID=1121256 RepID=A0A1M5F2E1_9THEO ---PLKQKIAEYISANKLSAGIYFKDITTNTTF-GINEDKMFVAASTIKVPIMLYLYTLAA -EKKVDLNTKIAYDREDFESGAGILEYIAKQGYSLRTLANQAITTSDNIANRMIMRYL-GK -ENIIKFMKDLGGQTV------------YPG-GKNITTAKDLVTYMEAVIAFSKANPELGE -TFLNDMAHTVY-NAGIPALLPDKLFIPHKEGDLDD-VANDFGIVYCQ--RPYILAILTNK -NK-NADTGFKHIANISKIIYDY- ->[subseq from] serine hydrolase n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=UPI000DD44103 ------KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE -EGNIDYLQKIKVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDMV-SM -DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ -MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD -IPNS-VYGTITLAKTGKMIWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces thermoviolaceus TaxID=1952 RepID=UPI00143AB71D -----AEAIAADWAALGMRGSFLARRLDTGEQL-GFDIDDPVPLASVVKVPFALVVLDRIA -AGLLDAAQPVTVDPATSSVGSTGLAARHPATVAVGDLLALMLAVSDNAAADALFDLV-PP -EETDARLREWGCTDIRVRHRMQRMYETLDPAHANAGTARGLVDLLQRVWQDEIARPAATA -ELRRLMAAQVF-THRLAGDLRDTIRVSGKTGTFLH-LRHDIGVVEADSGHRVAMAALTRS -DRALAPDIDAAIAAAARQAF--- ->[subseq from] Serine hydrolase n=1 Tax=Nocardia sp. CICC 11023 TaxID=2545717 RepID=A0A5N0EF48_9NOCA ----------EIFRDAGVRGWVHARCFDCGAEA-GSGADEPVVLASVVKVPLVLEFARQVA -AGQVDPADRVRAGGADRLGGVGTAGCHDDVELSLRDAAFFALTVSDNTAADLLFDRV-GI -DNVRSLVRELGLDATRIVGAPRHIVQALDPLRTTASTPREMTRLLTLIGQDLAGPAEACG -WVRDLMRRQVN-WHRLAGAFPPEVQVWAKTGTLP-GVRNEIGVLEYPDGSRYAVAVFTRV -ESQRLPEVDRAIGAVAAHA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ297 TaxID=2572905 RepID=A0A559V971_9ACTN ----VAERIGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASVFKIMVVLEFARQAA -AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -ERARRIDVDLAMGEAARTAVD-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A6B1N2I1_9ACTN ------AALESVIAEAGVTGFVHARDIDHGHEI-GVRADEPVIVASLRKIPVALAYARRAA -AGQLDRAARHTITADNREGGGIGTDSCLHDVMSTRDLAFFMMSMSDNAATDKLMEIL-GV -DYVRRVAAKSGCPRIPVGRYRDLWDPMLDARRSVSSTPREITTLLTAIWRDEAGPAEACA -EVRDLMGHQLS-THRLIAGFDDDVRVAAKNGSLW-GVLNEAGVVEYPDGGRYAVAVFLRT -PQGRNPAADAAIARAARTAVD-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium sp. C8 TaxID=1667357 RepID=A0A0G9LDC4_9CLOT ------KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQMVAAGCMKLPIAVSLIKAVE -DKKIDFLDKIRIDGKDKVFGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDIV-GM -DKINKNIEEMGLKNTVLNRKTTDER-KVKNEVENITCALDLAKVWRHLYNATYLSKENSQ -MLIDILTRQQI-KNKLALYIPDDYEISSKTGDKN-GVENDTELIRLSKGN-FTFTLLSMG -IPN-SVYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI000A17A1F0 ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNQLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] Serine hydrolase n=1 Tax=Rhodococcus sp. EPR-157 TaxID=1813677 RepID=A0A164PHQ4_9NOCA ---------------AGCRGWLRAQRIDDGPVV-DVNGHEPVVAASVYKLVVLVAAARAFD -SGHLDPHTQVRVVPADCTPPTGISTFTDPVTLSWLDLVRSMITVSDNAAADILLGAL-GF -GIVEQIIDEFELSDTRIVGGTAALQGAYDPAYTTATSAADINALLSAIWEGRAASPRMTD -NMKTIMSQQIW-PHRIRSALPADVTVAGKTGTIGP-IRNEVAVVVFPGEAPIAVSVFTRA -ARSDLPLVDQAIGRVARIAVT-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 94 TaxID=2035218 RepID=A0A2G7AH86_9ACTN --------------------------PGEAREV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDVLDVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS -HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART -REATRPTVDAAIGAAAGIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048D4472 -------------DRTPGTVSASLGHLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGTLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Beta-lactamase class A-like protein n=3 Tax=candidate division WWE3 TaxID=422282 RepID=A0A0G0Y287_9BACT ---KVETQFLELTKKLPGVYGLYIKDVGSGKEF-KYNESTEFYAASLYKVPIAAAVLKEVE -AGRLKLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY -KNVQETFNAV-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGDYLSADDKK -YLSDLMTNTSF-EDRISAYLKEGLVFSHKIGSWPD-SWHDCGVVYTENRESELMVCLMSQ -R---------------------- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium disporicum TaxID=84024 RepID=A0A174DS65_9CLOT ------KEIKRYLESRIGTYGFFFEDLKSGYVY-GYNENVSMTAAGCMKLPIAVSLIKAVE -DGKVDFLDKIKIQSEDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIL-GM -EKINQDILEMGLKNTKLNRKTTDERD-NHTDIENLTSAYDLNLIWKHLYNGTFLNKDNGQ -MLIDILRRQQI-KNKLALYLCDDYEISSKTGDKY-GVENDTEFIQLPKGD-FAFTVLSSG -LPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Synechococcus sp. CPC35 TaxID=2024880 RepID=A0A2D4YW83_9SYNE ----------LAAQQKDLQASAYMLILDDGRFA-QMNAERPMPAASAIKTPILLAALELID -SGELKWNEPLTLNKELVGGGAGWMASRPLGSFPTHEVATEMIRISDNSATNLLIARAGGK -EKINARFQAMNLPATVVNNWLPDLDGT------NTTSARXLSRAIALVDSGETLAPRSRD -LFXEVMATSVT-NTLLPTGLMRGYRVYNKTGDIGI-AYAXAGLIEMPXGRRAVAGFLVKG -PFN-DPRSTELIRRLASAMA--- ->[subseq from] Beta-lactamase class A n=2 Tax=Edaphobacter aggregans TaxID=570835 RepID=A0A3R9R114_9BACT ----LQQELAALVEKHHGKVALYATQLNTGKSV-AIDADRPVQTASVIKLTILFEAMEQVR -AGKARWDEKLTLVKGDGVSGSGVLTFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRF-GV -DAVNARIAWMGLKDTHLYKKIGKPATDQPKFGLGKTTAREMAMVMERIGRCQAGDAAICE -VALKMLRNQFY-RETIPRYLETGSGIASKTGSLN-AVRADVAIVAGKTG-PMVLSIFTFD -NEDKDNEGEVLIGRLAKTIVEAw ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04169 TaxID=2203197 RepID=A0A429C8P8_9PSEU ---EVTETISERAKEAGVRVRLHAAEIDGTRHI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHTCATTAEEITRLLGLVWRDEAAAPAACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Tsukamurella pseudospumae TaxID=239498 RepID=A0A138AJ22_9ACTN ----ARERIEAVFADAGCNGWLHARVIGDGAEL-SVRGGQPVVPASVYKVVLLVAAARAVD -AGRLDPRARVVVDPATATPPTGLAALSDPVEMSVRDLLRSMVAVSDNAAAGVVMRLV-GL -DAVQMTARDLRLNDTRIVGGDAEIHAAYDPSFGSATTATDMTALLAAVWSDTAASAEQCA -FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVGYPGEHPVAVAVFTHA -ARPSLPLVDAAIGRVAAIAVD-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A0Q8DDW5_9ACTN -----------------------------AGEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRHVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -RVRELMARQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAAIGATARIAVDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. SLBN-172 TaxID=1813332 RepID=A0A542N9E5_9ACTN -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPIAVHPDE--MQDPATWEAIGSSLPLGDLVRRSLTVSGNLAVNLVLERV-GL -AEVAAVLDDAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA -ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis keratiniphila TaxID=129921 RepID=R4T8A4_9PSEU ---EVTETISERAKEVGVRVRLHAAEIDGTRQI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -EATEKTLRDLGFEHTTVSQDCGEVLRALRPEHTCATTAEEITRLLGLVWRDEAAAPAACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TPG3_9ACTN ---------------------------AGGREV-AVGADEQVVIASIFKILLVLEFARQVT -AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLARTRIVGGPRQLVEVFDPERTTSSTARDITGLLGLIWRDEAGPAAACA -MVRNWMARQLF-WTRLATGFPPGVRVAGKTGTLP-GLHMEAGVAEYPDGGRYAIAVFART -AQTRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL B-1347 TaxID=1476877 RepID=UPI0004CA2054 -----------------GAPGAAAAPVADGQAGvSVAADTPVALSSVFKVLLVLEFARQAA -AGQLDPRERVLVTDEHRLGGWGTAGCVDDVEISLRDLAYFALTVSDNSAADILLSRV-GL -DTVGLLARELGLARTRVVGGPREALAVLDPRRANASTPREVTRLLDLIWRDAAGPPEACA -QVRELMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS -RAADLTRVDAAIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. EV170527-09 TaxID=2603411 RepID=A0A5B0ID18_9PSEU ------------------------------RDV-DAGAHAPVVMASVYKLFVLVAYCREVD -AGTVDPREPVVVPVPRTPGPTGISALADPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR -DRVAALPAELGLSGTRIRGGTDDVFAALSPVYGSATTAADVTALLALLWRGELASEASTA -FARRLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS -ARTTVPRADAAIGAAARVAVH-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonosporaceae bacterium TaxID=1873464 RepID=A0A3D4WT02_9ACTN ----------EIFDKVGVDARLHVVDVDTGREV-GMRADEQVVIASVLKILLVLEFARQAV -AGQLDPTERVMVRATDRLGGWGTAGCADDVELSLRDLAYFAISVSDNTAADLLMRRI-GP -DVVPLLTAELGLIRTRVLGGPRQVLEVFDPAHTTSSTAREITRLLTLIWRDEAGPPAACA -MVRDLMARQMF-WTRLPSGFPPDVRVSAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAQT -QRLNTR----------------- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=A0A6B2DSX5_9PSEU ---------------------LHVRRLGSPAAT-GIGADSPVVLASVVKVPLAYEFARQVA -AGLLDPADRVRATAADRLGGTGSAGFADDVSYSLRDAARLALSVSDNTAADLLFDRV-GV -ANVRSLLAELGLTRTSVIGAPRDLLAALDPSRTSATTPREMTALLAAIWADPVAEP---- --VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG -GAETRPDIDRAIGDAAHAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Pseudonocardia sp. P2 TaxID=882856 RepID=UPI0003086580 ----------------------------SDRDV-DAGAHAPVVMASVYKLFVLVAYCREVD -AGTVDPREPVVVPVPRTPGLTGISALADPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR -DRVAALPAELGLSGTRIRGGTDDVFAALSPVYGSATTAADVTALLALLWRGELASEASTA -FARRLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS -ARTTVPRADAAIGAAARVAVH-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNZ303 TaxID=2512144 RepID=UPI00104C6091 ---------------------------DGRREV-AVRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA -MVRGWMARQLF-WTRLATGFPPGVRVTGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFVRA -TQTRRIDVDLAMGQAARAAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID1034 TaxID=2690248 RepID=A0A6B1NVA8_9ACTN --------ITAALTDAGLGGALCATDIDTGATV-ALAADTPVSTASVHKLCLVATLYREAA -AGRLDPTTPVDIPAGARAPPTGLAVMRDAARLSLRDLASLAVAVSDNAAADILWDHL-GL -DTVNATMNALGLTRTIAVHNQAGLYAVLDPARTNRSTPREITALLTAVWRDEVCDGAWGE -ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA -ASATLPAADAAIGRAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C92F33 -----------------------------AREI-AVGADDAVVIASLFKILLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL -DTVRLLAKELGLERTRVVGGPRDLLEVLDPRHTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMGRQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -HDASRATVDAAIGRAAGI----- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC201 TaxID=1848320 RepID=A0A4R4NHC3_9ACTN ----------DHARELGADIWLHARDLATGRSV-GVGESTPVVTASVLKVPVALELARQSV -AGEVDLTERITVPPGGVPSPYGLSVQRDDTVISYRDLAHLMIVISDNVATDLVIGRV-GK -DRVAALLAELGLTATAVPQDCAEILAALVPERTCRTTPEEITRLLAGIWRDEAAPPEACA -LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEYADGGRYAVGVFTRA -GDPNAPHLDALIGWAAAN----- ->[subseq from] Putative beta-lactamase n=1 Tax=Microgenomates bacterium 39_6 TaxID=1641391 RepID=A0A124FZA6_9BACT --kELQEELLELIGQERGVYGVYLLAAESQNAI-GINHQKIFPGASLMKLPVIATAYQEAE -KGRFDLTAEYRLKEEDKLVGNGSVHLQPEGTYTYQALIQLAIEQSDNTAVSVLADNL-GK -EKIQALIDFSGLSRTDYLAGE--------------TTPEDIGQFLFSLHQGKMLTSSHSQ -EFIGFLTNTIF-NDQIPSVLPENLVVAHKIGLDEN-LLHDAAIIFTDKGD-FILVIMSQG -DSQD--RAQMILEEITKMIWK-- ->[subseq from] serine hydrolase n=1 Tax=Natronorubrum texcoconense TaxID=1095776 RepID=UPI000B7EE640 -----RSAAKRIDERLDGRLGMVVCDAGSTPLV-AIRPTERFGAASLVKLPILYALYRTYD -GRLADLDRPHSIAPENRVGGDGLFHLLSDPTPTTEDLATAMISVSDNAATNELIDHL-GF -DAIDEGAADLGLEGTRLGRKMMQTPASNGHRYVNWVTPRDCATLLSDIHGGRTLSSAAYE -RLARPLAHQHD-GSMVPRYLPPDVDILHKTGNLPS-VAADAGLLTVGER-TVAYAICCDG -LE-HRGEGVDAIAELSAGVY--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces fungicidicus TaxID=68203 RepID=A0A494UG99_9ACTN ----------------------------GGREV-AVGADDAVVIASLFKMLLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLHRV-GL -DTVRLLAKELGLERTRVVGGPRDLLEVLDPRRTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARFPDGECYAIAVFART -HDASRATVDAAIGRAAGMA---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. XY152 TaxID=1415560 RepID=UPI0006AF11F2 -----------------------------AREI-AVGADDAVVIASLFKILLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL -DTVRLLAKELGLERTRVVGGPRDLLEVLDPRHTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMGRQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -HDASRATVDAAIGRAAGI----- ->[subseq from] Beta-lactamase class A n=1 Tax=Kitasatospora viridis TaxID=281105 RepID=A0A561SEL4_9ACTN ---AARARIADAFADAGVSGLLHARDLDGPAEL-AIGADTPVATASVHKLCLLTTLFREAA -AGRIDLTRQVEVPAAGRTGGPTGLAAMLDPALSLRDLAYLATAVSDNAAADLLWDEL-GL -DLVNRTMADLGLTRTVAVHRLRDLLAVLDPAATNRSTPRELTELLTAIWHDRACRGEHGA -ALRRLLGLQVW-PHRLASGFPDDVRVYGKTGTLPT-LRHEVGVVEYPDGGRYAVAVFTRA -AATSLPAADAVIGTAARLAVD-- ->[subseq from] Beta lactamase n=1 Tax=Streptomyces griseoflavus Tu4000 TaxID=467200 RepID=D9XN01_9ACTN ----------------------------GGREV-AVGADDAVVIASLFKMLLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLHRV-GL -DTVRLLAKELGLERTRVVGGPRDLLEVLDPRRTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARFPDGECYAIAVFART -HDASRATVDAAIGRAAGM----- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ303 TaxID=2512144 RepID=A0A4R2B4E0_9ACTN ---------------------------DGRREV-AVRADEQVVIASIFKVLLVLEFARQVV -AGQLDPRERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA -MVRGWMARQLF-WTRLATGFPPGVRVTGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFVRA -TQTRRIDVDLAMGQAARAAV--- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus jeddahense TaxID=1462527 RepID=UPI0005963129 ---------------------------SGEEQI-AFNEKEQLRSASIIKLFILATAFYEQE -KGNLSLSEQVCIPPSEIVGGAGVIPYLSGEQYTYQQLLELMIIVSDNTATNALIDFI-GL -DNIHAFIQSIPCKHTKLERKLMDQ-DAIKAALENKTTCYDVMLLLDLFTEQNILPKHCQE -QILAILENQQF-NSKLTASYDSTIKTYHKTGELT-GAEHDAAIFQTSEIQ--LKAVMLTE -GWANNGEGQQFHQSAGAHIYRY- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis benzoatilytica TaxID=346045 RepID=UPI0003813D54 ----ATEKILRRANEIGVEVWLQAADVDGTATF-GIGADVPVVTASVFKIPVALELARQAA -EGLRDLGDRIAVRPGHPTPPYGLATFRHEVVMSWHELAILMIGISDNVATDLILAEI-GK -DSVNATLRRLGLARTAVPQDCAELLAALQPENTCRTTAAEMTRLLGLIWRDEAAPPQACA -DVRRWTGLQVW-PHRLRSGFPDGIRTSGKTGTLPS-VRNEVGVVEYPDGGRYAVSVFTRA -EDSRVPERDAFIGFAAATAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. BP25 TaxID=2048900 RepID=A0A2G4KFP5_9CAUL --kALQKAMERLAARAPGVLGVAAEDLGTRQVW-AFNGDRPFVLGSAVRVPILAAVMADHA -AGRLDPNEVITVRDVDLSPPSAVADAWPGRKYTVAAL-EALARAGDNTALDLLAKRIGGP -GGVNGLLAVRQLEGISVDRYRRQAETRRAVDQRDTATPVGLVRLLEAFNTREVFASAEPR -LLLG----ND--PGYLATALPAGARIWQAAGANRNDESHAVALIELKDGRRVALAAFLSG -STANAAAREAILSEAGRTVLKSf ->[subseq from] serine hydrolase n=1 Tax=Lactobacillus sakei TaxID=1599 RepID=UPI0009771D4C ------------------------------------------------------------- -------------------------------NHSVDEWIQLMIQQSDNNATNLLIDFA-GM -TEINQYIQQQGYTQTKLERKMLDD-AARNQGLDNYTSVKDVLQFLNLLYQNR--DQAPYS -KMLTIMKGQQT-RTKIPSQLPANTVVANKTGELAD-VENDVGIVFKDND-PFAIVVLTNQ -VQNPAAERQA-IGA--------- ->[subseq from] hypothetical protein n=1 Tax=Hungateiclostridium alkalicellulosi TaxID=320502 RepID=UPI0011E73EA6 --------IDKHVKNLDKNIRISIYDFATNTSV-NYNGFDKFYPASLSKVLNLLCYLKEVE -KGNLSLYNTYTLKESDKYVESMVVQQEEGTQYSYNDILFRMISLSDNVAANIIIDAL-GY -NKINSLSKNYGLKDTMIYRKFYEMNSPVP---VNFSTAYDLTKMLVLLENRTILEDGLSN -IGIDFMKKTYN-KDRIALYAPDNVVIANKIGSLSR-LSGDMAIVYFENREPIALTIFVED -KNIDNQEVNHVIGELSKEVIDYy ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. e14 TaxID=645465 RepID=D6KD09_9ACTN ------------------------------------------------------------- ------------------------------------------------------------- ----TRLVRALGDPATRLDRTEPHVNDA--DGVLDTTTPAHLAADLRALTLGHALEARDRD -RLLAWLDASTTGDRAVRAGCPRGWRIGDKTGSGSHGESNDVAVIRPPHRAPLVLTVFTAP -ADPRSTAGQPTIAEAARIVA--- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=unclassified Microgenomates group (miscellaneous) TaxID=1794839 RepID=A0A0G0WWX4_9BACT -------------------YSILVVDTKSDFRV-AINDTEMFTAASVNKIPILAALYIGIQ -NTDIDPDTVITVQEEDIQDTGSIRYDGAGSTYTIKTLARLMMQQSDNTAAYILANHIIRL -DTIQSLLNEWGMTQTDMIN--------------NKTANNDVYKIIKKIYQGNIANPAYTQ -EMLAFFKDTEF-EDRIPGLLPKTVQVYHKIGSEI-GYMHDVGVVVAPSIT-YYIGIFTSD -IT-NEKEATKLMAEVSKLVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium algidicarnis DSM 15099 TaxID=1121295 RepID=A0A2S6FZK6_9CLOT ------KEIKKYLESRIGDYSFYFEDLDGGYIY-GYNENVPMISAGCIKLPIAMAILKESE -IGNISLNDKLSVSIDDKVSGNGIIHEFEEKEYSLIELLIAMLIQSDNTATNKLVDLV-GM -SKINSIFKEMDLKSTKLNRRVEKEK-DVDSRIQNITSSYDLCLCWKHLYNSSYLNKENSN -WVIRIMKKQQM-KNKLAFYMGEEIKIANKTGDLS-GVENDTSFIQVPKGN-FAFTMMSKG -VPND-VYGIVTLAKSGKMMW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora kangleipakensis TaxID=1077942 RepID=A0A4Q8B9K5_9ACTN -----------------GNLHVVEVDGGAGREV-EVRADEQVVIASVFKILLVLEFARQAA -AGQLDPTERVLVRADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVVPMLAAELGLSRTRIVGGPRQLVEVFDPAHTTSSTARELTRLLGLIWRDEAGPPAACA -TVRELMGRQLL-WTRLASGFPPGVRVAAKSGTLP-GLHLEAGVAEYPDGGRYAIAVSART -ERLDTRDVDLAMGEAARVAVE-- ->[subseq from] Beta-lactamase class A (Fragment) n=1 Tax=Streptomyces sp. SolWspMP-sol7th TaxID=1839776 RepID=A0A1C4Q503_9ACTN --------------------VVHAVDIDRGTET-GWEADRLVCTASVHKLCLLLALHRLAA -AGRIDLTERVECPVEGRTPGTGLAAMLDAPRMSLRDLAYLMIAVSDNAAADLLLARV-GL -EEVNRTTEALGLRRTRAVESFAATQEALDPAHGNRSTPRELTRLLAALWRDEFLPEPHGA -AVRRLLGLQVW-PHRLASGFPDDVQVFGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADT-------------------- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536A8A1_9CHLR --qDLVRQLDGLVSGFAGGTGVWVSDPSSPTPLfTHAPDEQVITASLYKLGVLAEAERRVD -SGELHYNDPVLIAPEDVTSDGSFE--EAGTSLTLDEALESMITISDNGAALALWHILGGS -----------NIDVTLTKAGMADFHVAYDDSEDNWATPRALGTFFTLLAKRQLISAAASD -RMLARLERQQI-NNRLPAQLPPDVLIAHKTGNLP-GLTHDAGIIFTKAGPRVVVAMTWDA -LD---EDADSFISSVGALVY--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000364FFDC ------------LDRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces spectabilis TaxID=68270 RepID=A0A516RM49_STRST ----------------------------ARADV-SVAADTPVAISSVFKVLLVLEFARQAA -AGQLDPRERVLVTDAHRLGGWGTAGCVDDVEISLRDLAYFALTVSDNSAADILLSRV-GL -DTVGMLARELGLARTRIVGGPREALAALDPQRANASTPREVTRLLDLIWRDAAGPPEACA -QVRELMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS -RAADLTRVDAAIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. BL4 TaxID=2478710 RepID=A0A3L7B7U4_9ACTN ----------------------------GGPEV-GVRADEQVVIASIFKILLVLEFARQVV -AGQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA -DRPRRIDVDLAMGQAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis kentuckyensis TaxID=218823 RepID=UPI000A3BFFE2 ----------------------HAREIGGGPSV-AVGADDPVVLASVFKILVAVAYAREAA -AGRLDETARTRVGPRYRIGGIGTAGCADDVEMSWRDLALVMLTMSDNAATDVVYHRI-GA -AAVDRVPADLGLHRTRLIGCCEDLFAVLDPERTTSSTPREITELLDAVWTDRAGDPAACE -RVRSMLARQIW-PHRLSSGFPSDVGVAAKTGTLPS-VRNEAGVVSYPDGRRFAVAVFTRA -NSDRQPAIDAAIGRAGRLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis lexingtonensis TaxID=218822 RepID=UPI000A367519 -----------------VRGFLHVRRLGSPAST-GVGADAPVVLASVVKVPLAYEFARQVA -AGLLDPTDRVRASAADRLGGSGSAGFADDVSYSLRDAARLALSVSDNTAADLLFDRV-GV -ANVRSLLAELGLTRTTIIGPPRDLLRALDPLRTSASTPREMTALLAAMWGD-----PAGD -QVREWMAAQVS-WHRLTAGFPPEVAVVGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG -GAETRPDIDRAIGDAARAAVEQ- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Amycolatopsis sp. M39 TaxID=1825094 RepID=A0A178XFM2_9PSEU -----RARIEAVFADAGAEGFLHAREIGPGPEV-SAGGDAPVVLASVFKIPVALAYAREVA -AGRLDDTERTKVTARYRIGGIGTAGCADDVEMSWRDLAHFMLTMGDNAATDVLYHRL-GQ -EKVDRVLADLELARTRLIGCCEDLFAVRDPERTTSSTPREITELLDAIWTDRAGEPQACE -RVRTIMAQQIW-PHRLSSGFPPGVAVAAKTGTLP-GIRNEAGVVTLGDGRRFAVAVFTRA -QSDRLPAVDASIGAAARLALDH- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A1C4VBS9_9ACTN ------ERVAEIFGRAGLRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMLVLEFARQAA -AGQLDPTERVVVGPADRLGGWGVAGCADDVEISLRDLAYLAMSVSDNTAADLLLRRV-GA -DVLPMLAAELDLPRTRIVGGPRQLAEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -ERARRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces agglomeratus TaxID=285458 RepID=A0A1E5P1Q6_9ACTN ------ERIREVFAGAGAEGLLHAVPVGTEEEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAISVSDNSAADLLLARV-GL -DTVRLLAGELGLGGTRIVGGPRDVLEVLDPLRTNASTPREITRLLRLVWRDEAGPPEACA -HVRDLMMCQAF-RHRLVSGFPDEATVAAKTGTLP-GLHMEAGVVRYPDGGSYAVSVFART -RDASRPVVDAAIGASARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2573 TaxID=2512224 RepID=A0A4R8C459_9ACTN -----NARIRAVFEDAGVRGWLHAVALDEPESTvEVDADGIVPLASVYKLPLLAGFCRLVD -LGEIDPRQQLTLDPSTKTSGPTGLSTFADPVASLRDLALSMMTLSDNASADALLDVV-RL -QRLAELLKSFGLQRTWVRRGTAGNLRVYEAANASAASARDMTLLLRRLWAGELLSPEQTE -FVKATMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGTAYAIAVFTLA -ARGDQPRVDAAIGEAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. OV198 TaxID=1882787 RepID=UPI000BD5DA38 ---------------------------GEAREV-AVGADEPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDVLEVLDPLRTNASTPRETSELLRLIWRDEAGAPEVCS -HVRDLMSRQVF-RHRLVSGFPDDVTIAAKTGTLP-GLHMETGVVRYPDGGCYAVSVFART -REATRPRVDAAIGAAAAMAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04197 TaxID=2203199 RepID=A0A429E8W5_9PSEU ---EVTEKITERAKEVGVRVRLHAAEIDGTRQI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPDGLATFRHEITMSWYDLAILMIGISDNVATDLILERV-GK -EATEKTLRDLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA -DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Rubricoccus marinus TaxID=716817 RepID=A0A259TWE7_9BACT --sELQSAVEKLARGFRGRVGVYVRHLPSGRSA-ALRADSLFPTASMIKVPILVATMEAIH -RGDLAWDEPLVFRDSLRYDDHGLIGLLRDSAIELHVAVEAMLSASDNNASLWLQSLSGGG -ARINEILAARGYTGTRMNSGTDGRRADWERYGWGQTTPREMSHLVREIVDRDIVSPQADE -RMHRALTRTFW-DGEALSAIPPGVQVASKQGAVS-ASRSEVLYVHAPSG-PYVFTVITDA -QEDQ------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. KhCrAH-43 TaxID=1305827 RepID=A0A327U430_9ACTN ------TALRAAFTDAGVTGRMHALDIVSGAEL-DVCGDELVCTASIHKLPLLVTLHERAA -AGDLDLTEQTDCPPLGRPAGPTGLAAMLDVALSLRDLAYLMMAVSDNAAADLLLDRV-GL -DAVNRTAARLGLSRTIATHSFGEMMAALDPAWANRSTPRELTRLLAAIWRDEACTPENGD -AMRRLMALQVW-PHRLASGFPDDVHVAGKTGSLPT-LRGEAGVVEYPDGGQYAVAVFTRT -LSAIVPAADAVIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Natronorubrum texcoconense TaxID=1095776 RepID=A0A1G9D973_9EURY -----RSAAKRIDERLDGRLGMVVCDAGSTPLV-AIRPTERFGAASLVKLPILYALYRTYD -GRLADLDRPHSIAPENRVGGDGLFHLLSDPTPTTEDLATAMISVSDNAATNELIDHL-GF -DAIDEGAADLGLEGTRLGRKMMQTPASNGHRYVNWVTPRDCATLLSDIHGGRTLSSAAYE -RLARPLAHQHD-GSMVPRYLPPDVDILHKTGNLPS-VAADAGLLTVGER-TVAYAICCDG -LE-HRGEGVDAIAELSAGVY--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inositola TaxID=47865 RepID=A0A1C5H0L2_9ACTN ---------------------------GAGREV-AVRADEQVVIASVFKILLVLEFARQAA -AGQLDPTERVLVRAEDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVVPMLAAELGLPRTRIVGGPRQLVEVLDPAHTTSSTARELTRLLGLIWRNEAGPPAACA -MVRALMGRQLF-WTRLASGFPPGVRVAAKSGTLP-GLHLEAGVAEYPDGGRYAIAVSART -ERLDTRDVDLAMGEAARVAVE-- ->[subseq from] serine hydrolase n=1 Tax=Tsukamurella sp. 1534 TaxID=1151061 RepID=UPI000A30DE79 ------EEIAAVFADAGCNGWLHARVVGHPARL-SVGGEQPVVPASVYKLVLLVAAARAFD -AGRLDPLERVTVDPRTATPPTGIAALDDPVEMTLRDLLRTMVAVSDNAAAGTLLRRV-GL -DAVQATATALGLADTRITGGDAELYAAYDPSFGSATTAADATALLAAVWSDAAASPEQCA -FVRSALAGQTF-RHRVASGFGSAARIAGKTGTLG-ALRNEAAVIAYPDEHPVAVAVFTHA -ARPSLPRVDSAIGEVAAIAVN-- ->[subseq from] Uncharacterized protein n=1 Tax=marine metagenome TaxID=408172 RepID=A0A382FFM2_9ZZZZ ---ALENELNQLCDEQPFHTGWSVKNLRTGTVL-ERHGSVVVPSASTRKIAIMMAALKAVN -EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL -EAINALCQSIGMADTVHRYGIPGMAGYLPAEKTNSTTPADVARLLELILKGVGCTSELCQ -LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYADGVPLFLISAYTDS -VPVE------------------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora terminaliae TaxID=1914461 RepID=UPI0012AEC86B ------ERIGEIFERAGISGCLHVEDVDPGRAV-ALRADEQVVIASVFKILLALEFARQVV -AGQLDPVERVLVGAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTAREMTRLLGLIWRDEAGPPTACA -MVRELMARQLF-WTRLASGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART -ERLSTRDVDLAMGEAARAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora lupini str. Lupac 08 TaxID=1150864 RepID=I0KXI6_9ACTN -----------------------------DRQV-GVRADEQVVIASIFKILLVLEFARQVD -AGQLDPTERVLVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DEPRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=UPI00128D2EA7 ------------------TGFLHAVDVGSGVEV-GVEPDAPVVTASVFKVSVLVELCRQFA -TGEREPADRLRVPAGARTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -DRINALMVELGLPGTVLEEDCAGLFRVLDPRTTNRSTPRETTTLLRRIWAADGLPAAAGE -EIRRIMALQVW-PHRLTSGFQDDVKVSGKTGTLSH-VRNEVGVVEYPDGATFAVAVFLRL -PGGENPAADAVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis sp. SID8362 TaxID=2690346 RepID=UPI0014153069 ----------------------HVRRLGSPAAT-GIGADSPVVLASVVKVPLAYEFARQVA -AGLLDPADRVRATAADRLGGTGSAGFADDVSYSLRDAARLALSVSDNTAADLLFDRV-GV -ANVRSLLAELGLTRTSVIGAPRDLLAALDPSRTSATTPREMTALLAAIWADPVAEP---- --VREWMSAQVS-WHRLTAGFPPEVAVAGKTGTMP-GIRNEIGVATYPDGVSYAIAVFTVG -GAETRPDIDRAIGDAAHAAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Bifidobacterium psychraerophilum TaxID=218140 RepID=A0A087CGN2_9BIFI -----------SAQAKGITVGATFQDLSGGGSLsAGAHGQAFKAASTIKLGITSYLMHGVD -QGKWSLDTPITVESSDVVGGAGTIQSDVAALFTLSELMRLMITVSDNTATNRLIDFAGGF -DKINAYTQSVGDSGFHLGRKMILPHTA---EEENWISSDEDAKLLTLIYRGGIISQESAK -QVIAWMRQQTV-NTKFGAVIPRE-VLANKTGENTD-VSHDTGYVLVPGRE-VALSVMTSF -DPTAFNTANEQVQAVAKVVYQY- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces albus TaxID=1888 RepID=UPI00068E3B00 -------------------------------EV-AIGADDQVVIASIFKVLLVLEFARQVV -AGQLDPRERVRVSAADRLGGWGTAGCLDDVDLSLRDLAHFAMSVSDNTAADLLLARV-GL -DTVRLLAQELGLRRTRIVGGPRALLEVLDPRRTTSATPREITRLLRLIWTDAAGPPEACA -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGALYAITVFART -HDASRPTVDAAIGRAAGIA---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. me109 TaxID=1827853 RepID=UPI0011CD91CA ------------------------------REV-AVGADQPVVLASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAEELGLGRTRVVGGPRDVLEVLDPLRTNAGTARETTRLLRLIWRDEAALPEACA -QVRDLMSRQVF-RHRLASGFPGDTVIAAKTGTLP-GLHMEAGVVRYPDGRCYAVSVFART -RRVTGPEVDAAIGRAARIAVE-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium ventriculi TaxID=1267 RepID=UPI00073F07A3 ------KEVEKYLKSRTGKYGFFFEDLYSGYSY-GYNENVKLISAGCMKLPIAVALMKCEE -EGNIDYLQKIRVNSSDKVYGTGIIHEFGEKEYTVFELLVAMLIQSDNTAANKIIDIV-SM -DKINETIKELGMINTKLNRKTADERN-YISGIENYTSAKDLCILWKNLYNKTYLNENNSQ -MLIDILARQQI-KNKLALYITDDYEISSKTGDKK-GVENDTALIHTNKGD-FTFTVMSSD -IPNS-VYGTITLAKTGKMIWD-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00038131BA -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] serine hydrolase n=1 Tax=Bacillus gottheilii TaxID=859144 RepID=UPI00082ABC5F ---QFNRDVQRLTSAAHGRVSLFIES--DKGVI-EKDRHAVYPAASTIKIPILLEALRQAE -SGEIDLKQSISISPAHITGGAGILQSLYHPTMKLVDLLSLMIVVSDNSATNIIIDLL-GQ -NQIKQCINIMNLQETKLQRKMMDFEAG-RRGFENTTSAYDLGICLKFLTEDGLLNEESRA -LGLEIMGRQQF-RKLAYSVTSSKIAVYGKTGELP-GVSHDCVILKKEHHL-LYGVALI-- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SDr-06 TaxID=2267702 RepID=A0A367HJQ1_9ACTN ----VRSRLTAALTDAGLTGSLCATDIDTGDDI-TLAADTPVSTASVHKLCLVATLYREAA -AGRLDPSTPLDIPAIGRAPPTGLAVMRDAARLSLRDLASLAIAVSDNAAADLLWDHL-GL -DTVNATMAALGLHRTIAVHNQAALYAALDPARTNRSTPREIAALLTAVWRDDVCEGPWGE -ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-LRHEAGVVEYPDGGRYAVAVFTRA -ASATLPAADAAIGRTARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Terrilactibacillus laevilacticus TaxID=1380157 RepID=UPI00114086B4 ------EKLDRLVSPFGNKVSVVIQE--GKNHY-SFNESTKMLSASLIKLPIFLYAFDQVI -KGTLSLDQKIPISPEKMVDGSGIIQVIQDVRWSIRDLLGLMINVSDNTATNVLMDVL-GI -EQIQSWIENSGLNGTSIQRKMMDIQAK-KEGKENFTCASDVSQCMELIFLRPNSLSCEFP -FVKHYFLNQQF-RGKIPGKIESPVKIYNKTGEME-GISHDTAFMKLKDKT-SIVTCMTSG -FE-DATEADQLIQKMGEWVY--- ->[subseq from] Beta-lactamase n=2 Tax=Prochlorococcus sp. MIT 0601 TaxID=1499498 RepID=A0A0A2BHV3_9PROC ----------------------AYLNFEDGRYA-QLNAENSLPAASSIKVPILLIALEMLD -NKLLSWDELIELKRDLIASGSGWMRQRIGQKFPIHEIATEMIRVSDNTATNLLIDRIGGI -EILNKRFIELGLNQTHIKNMLPDLNGT------NRTSAKDLCQVFQIADSTNFLSLKSRD -LFREILSTSKT-NSLLPDGLLNGYRVYNKTGDIGI-SYADAGLIEMPDTSRATSAFIVKG -PFN-DPRSATLIRDLSAEIINH- ->[subseq from] Beta-lactamase n=2 Tax=Salinispora arenicola TaxID=168697 RepID=A8LX03_SALAI -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. MBT27 TaxID=1488356 RepID=UPI001423FDE5 --------ITAALTDAGLGGALCATDIDTGATV-ALAADTPVSTASVHKLCLVATLYREAA -AGRLDPTTPVDIPAGARAPPTGLAVMRDAARLSLRDLASLAVAVSDNAAADILWDHL-GL -DTVNATMNALGLTRTIAVHNQAGLYAVLDPARTNRSTPREITALLTAVWRDEVCAGAWGE -ELRAVLGVQAW-SHRLASGFPDDVRVSGKTGTLPT-QRHEAGVVEYPDGGRYAVAVFTRA -ASATLPAADAAIGRAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus selenatarsenatis TaxID=388741 RepID=UPI0014354C59 ----------------------------EGEMI-EFNSNEVYQSASLIKLPILFEALRQME -AGQLQKESQLPIEEGDKIGDTGVLQAMKVKQLPVVDLMSLMIIVSDNSATNLMIDLL-GK -DSINATISRLGMSHSILQRKMLDFS-AIQSGLDNYTSAADIGLCLKEGVKGDLLNQDSKS -IFHAFLLQQQF-KEKLPFYMDDTLEIGNKTGELP-GVEHDCGIIAYGEN-EAIIVVLIDE -LSNP-QSGKSTIQQIGKHI---- ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A6A8N275_9ACTN ----LDSEVARIAERCSGVLGVEAWNLNGEEKV-SFNSKELFPTASVIKLPILVALYSQVM -MNEVDLSERIDIDVRQHLGGSGILKVFESGLPTIKDVATLMIVLSDNTATNLILDVVGGV -DPVNSLMESLGFPSIRLHNRIDFEAIGSDIRRLGESSAVEMCELNYRIAKGELLSPAISE -EIESILEQQQY-LNQFPRYMQPKIRVSCKTGFFM-GTRVDAGIVRFNGGGGFVYSVFNNE -CE--------------------- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Micromonospora sp. MH33 TaxID=1945509 RepID=A0A2P8AT53_9ACTN ------ERIGEIFQRAGISGCLHVVDVDPGREV-ALRADEQVVIASVFKILLVLEFARQAV -AGQLDPAERVLVGAADRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPAHTTSSTAREITRLLGLIWRDEAGPPAACG -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVVEYPDGGRYAVAVFART -ERLSTRDVDLAMGDAARAAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mucilaginibacter mallensis TaxID=652787 RepID=A0A1H2A6N4_9SPHI --sKLTKKLNALAKDFHGQVGIYVQNLKTGKSA-EVNADTLFPTASMIKVSIMCGLMDKIQ -KGELDYHQNLIFKDSLRYDTGDILGSVKNNDIALSKVAMLMITMSDNTASLWLQKLV-TG -EYINNWLQQNGFDNMRVNSRVKGRERIRSIYGWGVTTPREMCKLFTMIREGKAVSPAASE -RMYRNLSHIYWDDNAI-SQVPPYIQTASKQGFVD-ASRSETVLASAPHGN-YVFSIITNH -QKKHDNEGFILIRNVSALLWHYf ->[subseq from] serine hydrolase n=1 Tax=Streptomyces griseoplanus TaxID=66896 RepID=UPI0006E41FA7 -------------------------------EV-AVGADDAVVIASIFKILLVLEFARQVA -AGQLDPRQRVRVTSADRLGGWGTAGCLDDLELSLRDLAYFTMSVSDNSAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDLLEMLDPAHATASTPREITRLLQLVWTDAAGPPEACA -FVRDLMSKQVF-RHRLASGFPDDVVVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -HDTSRASVDAAIGRVAGIAA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Prochlorococcus marinus (strain MIT 9211) TaxID=93059 RepID=A9BB54_PROM4 ----LSKKWKELADEYDLEVSAYIL-FEDGRYA-QFNAEKSLPSASTIKIAILFLSLEMLD -DGKLRWDEEIELTKESIAKGAGWMRQSLGKKFPIHEITTEMIRVSDNTAANLLIERVGGL -DILNKRFKELGLMQTEINSLLPDLSGT------NKTSAKDLSKIMKLVDVSGLLSTKSRD -IFREVMSTSIS-NNLLPEGILKGFRVYNKAGDIGI-AYGDAALIEMPNSSRAVTALLVKG -PFND-QRSTNLIRDMAAQIIS-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_40_15b TaxID=1798594 RepID=A0A1F6I7B2_9BACT ---SLKETVDSSLKGTHGTYAVIIKNLRTGEYF-SQNEKRTYEPASLYKLWVLGAAFKQIK -EGKLNRDEIISRDARDLNEASDSAELTEGTVMKISDAIEQMITISHNYAALLLVSKI-RN -SNVSAFMREQGFSSSRLGQPP-------------RTTAEDIASFFEKLYTGAMVDGEYSK -RMLDLLSQQRL-NDRIPKYLPDDVEVAHKTGEIR-GFKHDAGIIFAKD--PILLVVLSES -NS--QQGAAERIAQLSKNVYYYf ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. KC310 TaxID=1848322 RepID=A0A4R4W4Z5_9ACTN -----------HARELGTDIWLHARDLASGKSV-GVGETTPVVTASVLKVPVALELARQSV -AGEIDLSERVTVPPGGVPSPYGLSVQRDHTVVSYRDLAQLMIVISDNVATDLVIDRV-GK -GRVAALLAELGLTATAVPQNCAEILAALVPEETCRTTPEEITRLLAGIWRDEAAAPEACA -LVRGWMGDQIW-PHRLTSGFPDDIVISGKTGTLPL-VRNEVGVVEFADGGRYAVGVFTRT -DDPNAPHLDALIGWAAAN----- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces resistomycificus TaxID=67356 RepID=A0A0L8KXU2_9ACTN -------------------------------EV-AVGADDPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAKELGLERTRIVGGPRDLLEVLDPRHTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMGRQVF-RHRLVSGFPDDVVVAAKTGTLP-GLHMEAGVARHPDGACYAIAVFART -HDASRPTVDAAIGRAA------- ->[subseq from] Serine hydrolase n=1 Tax=Acidithiobacillus sp. TaxID=1872118 RepID=A0A2G2KE75_9PROT ---TLENELNQLCDEQPFHTGWYVKNLRTGAVL-ERHGNAVVPSASTRKIAIMMAALKAVN -EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL -ELINVLCQSIGMVDTVHRYGIPGMAGYLPADKTNSTTPADVALLLEIILQGVVCTPDLCQ -LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYAGDKPLFLISAYTDN -VPAXHTVAYDLTARLSRLCWDE- ->[subseq from] Beta-lactamase class A n=4 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A0G0L4F0_9BACT ---NVLSKFEESTDRLTGVYGLYVTDLASGHSF-GIYENNTFQAASLIKLPVMVGMYMSEE -DGALSLNTRYILKTEDKVRGSGSLYNKPAGYISYRDLLKLMGKESDNTAFNICRKHL-GD -EKIQDIINGIGMKGTSLEK--------------NETTPADIGSFFYKLWNGQLLNMKNTD -ELLINLTDTSY-EDWLTAGVPESIRVAHKYGRET-GVVNDAGIVYSENP---YIAVMLGK -NV-VLKEADSIFPELSKIIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium saccharobutylicum DSM 13864 TaxID=1345695 RepID=U5MS21_CLOSA ------KEIKQYLESRIGTYSLFFEDLQGNYSY-GYNENVQMTGAGCIKLPIAVSVIKYVE -DGKASFLDKIKIEDNDKVYGTGILHEFNNREYTLFELLVAMLIQSDNTAANKFISIV-GK -DRINQDIAAQGLKNTKLNRKTSDESEE-DNRTENITTALDLSKIWKHLYNASFLNRENST -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKSN-VENDTALIRTKKGA-YTFTVLSMG -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase n=1 Tax=[Flexibacter] sp. ATCC 35103 TaxID=1937528 RepID=A0A1S6WDX2_9FLAO --dKMKTEILEIIKGKKFNIGISVRNSKGVEIF-AHNSNEKYKMYSVSKFFLALKVLHLID -NKTLLLNQDVSFAKSDLKAFSPLRDSNPEGIITLEKALYYIVNQSDNNVFDKLVDLSGGI -ESLNFYISSFTKNKNSF--SMSALYRDKEGTGNNVVTPNFSSLLLYKLMKNKIISVESKN -ILMPLLETSIN-NKRIQALVPKNLKSFHKGGTSDRVASNDIGIVYINEKDFFTIAVFISN -SLEDDAVNDEVIAKITEIT---- ->[subseq from] Serine hydrolase n=2 Tax=Clostridiales TaxID=186802 RepID=A0A3A9HSQ8_9FIRM -------------EALGEKWAVSAVDLADGAVY-GYYEDIKMQSASVIKVFIMATVYDRVC -------------YPKDTESAIYVQEQYEG---ELKALLTNMITVSDNDAANRLVELLGGQ -EVVNAFCRENGFEGTSLGRRFLEENPA----DDNYTTSGDCMKLLQDLYNGNCVCAEASE -KMLNMLKNQTR-TEKIPSGIPEGTVCANKTGEMPQGIENDIAIVYGEHGD-YILCVLSND -LDGRNEEAKKRIAEISGYVYEEf ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A355D766_CLOSP ------KEIKRYLETREGEYSFYFADLKSDYTY-GFNEDLKMVAAGCIKLPIAMAVMKEVV -NTNIFLDQLVTITNDDKVSGSGIIHELEGRQYSIKELIVAMLIQSDNTAACKLINTI-GK -DRINSIIHDMGLTSTFIKKYPSGEKED--FDNENITTSYDLCKGLALLSKGKVLNGEHSK -FILEVIRRNQL-TTGISFYWPKDVKTAHKAGSLEK-IENDIVLLNLEKGD-FVFVVMSRN -LP-SNVYGVSSLARVGKMMVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces violaceoruber TaxID=1935 RepID=UPI000998322E ------------------------------------------------------------- ----------------------------------------AAARQRHNTATNLPLDLLGGP -TAATAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE -RLTTSLVVNTTGDATIRAGVPAGWLIGDRTGTGAQGERNDVGIVLPPDRAPLV------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora coriariae TaxID=285665 RepID=A0A1C4V256_9ACTN --------------------------VAGGREV-GVRADEQVVIASIFKILLVLEFARQVV -AGQLDPTERIQVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPPQACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYLDGGRYAIAVFARS -DRLT------------------- ->[subseq from] Beta-lactamase class A n=2 Tax=Micromonospora citrea TaxID=47855 RepID=A0A1C6UH25_9ACTN ----------------------------RRREV-AVGADEQVVIASIFKILLVLEFARQVV -AGQLDPQERVLVTADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRIVGGPRQLVEMFDPAHTTSSTAREITRLLGLIWRDEAGPPEACA -MVRGWMGRQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGGRYAVAVFARA -AQTRRIDVDLAMGEAARVAVE-- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. HH130629-09 TaxID=1641402 RepID=A0A0M3UC36_9PSEU ----------------------------SDRDV-DAGAHAPVVMASVYKLFVLVAYCREVD -AGTVDPREPVVVPVPRTPGLTGISALVDPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR -DRVAALPTELGLPGTRIRGGTDEVFAALSPVYGSATTAADVTALLALLWRGELASEASTA -FARRLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS -ARTTVPRADAAIGAAARVAVH-- ->[subseq from] Beta-lactamase n=1 Tax=hydrothermal vent metagenome TaxID=652676 RepID=A0A160TR48_9ZZZZ ----LENELNRLCDEQPFHTGWYVKNLRTGTVL-ERHGSIVVPSASTRKIAIMIAALKAVN -EGELSLSQPVTMASRFKNNDSGCFQHLRSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL -EAINALCQSIGMEDTVHRYGIPGMAGYLPADKTNSTTPTDVALLLEIILGGAGCTSELCQ -LAIDILSWQRL-RNRIPARLPLGTKVAHKTGTTAK-NYNDAGIVYTDDVPLFLISAYTDS -VPADHTVAYDLTARLSRLCWDE- ->[subseq from] Serine hydrolase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1M1R3_MYCCH ------------------------------PIV-DVDGDRPAVAASVYKIFVLIAAARAFD -SGHLHPEATVRVAPADCTPGPTGISTFSNPVLTWLDLARLMITHSDNTAADVLLAAI-GL -DTVNELTEELGFNSTRIIGGTSALQRAFDPAYTTATSACDTDRALSAIWTGTATSAQSSD -MMKQILTQQIW-QHRIRSAFPRDVTVAGKTGTIGP-IRNEVAVIAFPGEPPMAVSVFTRA -ARADLPNVDRAIGQAARIAI--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00037C8C86 -------------DRVSGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Serine hydrolase n=1 Tax=Actinosynnema sp. ALI-1.44 TaxID=1933779 RepID=A0A1V2PK24_9PSEU ----VVETINDRAKEVGVRVRLHAAEIDGTRQI-GIDEGVPVVTASVFKVPIALELARQGA -EGELDLGERITVAPGHPTPPYGLATFRHEVTMSWHDLAILMIGISDNVATDLILAGV-GK -EAVGESLRRMGFEHTTVTSDCREILDALRPEHTCATTAEEITRLLAMIWRDEAASPTACA -DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVIEYPDGSRYAVGVFTDA -VDSRVPERDAFIGFAAARA---- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. or20 TaxID=1828016 RepID=UPI000BF00F2E -----------------------------AGEV-SVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAVSVSDNSAADLLLARV-GL -DTVRLLAEELGLGRTRIVGGPRDVLEVLDPLRTNAGPPRDITRLLRLVWRDEAGPPEACA -QVRELMARQIF-RHRFVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGLYAVAVFART -REASRTAVDAVIGATARIAVDH- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces olivochromogenes TaxID=1963 RepID=A0A250VI06_STROL ----------------------------EAREV-AVGADEPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCADDVELSLRDLAFFAMSVSDNAAADLLLDRV-GL -DTVRLLAKELGLDRTRIVGGPRDVLDVLDPLRTNASTPRETSELLRLIWRDEAGAPEACS -HVRDLMSRQAF-RHRLVSGFPDDVTIAAKTGTLP-GLHMEAGVVRYPDGGCYAVSVFART -HEATRPTVDAAIGVAAAIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. Maddingley MBC34-26 TaxID=1196322 RepID=K6U0Y4_9CLOT -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTAAGCMKLPIAVSVIKYVQ -DEKGSFLDKIKIEEEDKVYGTGILHEFDNREYTLFELLVAMLIQSDNTAANKLIDIV-GM -DNINEDIIAQGLKNTKLNRKTSDERAA-SSGIENITSALDLAKIWKHLYSASYLDKKNST -MLIDILQRQQM-KNKLALYIPDDFEISSKTGDKAS-VENDTALIHVQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=4 Tax=Corynebacteriales TaxID=85007 RepID=A0A1C2B1B4_NOCFR ----LDRAVHETFADAGCSGCVHVRTIGTPVEY-CHDADTPVVLASVYKLAVLVSLCRMAD -RGDIDLTASISVDPTRWAQGPTGLALFSDPVISWRDLATSMMTVSDNVAADVILAHI-GL -PQIHDDLVDLGLTHTRIVGGVAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASATSCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEIGVIEFPGEVPIAVAVFTMS -ARSELPEVDRAIGEVARVIVT-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=marine sediment metagenome TaxID=412755 RepID=X1DVJ7_9ZZZZ --eRLKKQIEGIIHGTEGEVGVAVKHLESGQEL-YINGDINFPMASVFKVPILVEVLAQIK -EGKFALKDEISIQKTDQHLGSGMLSDLEAPGLSLRNLITMMMIISDNSATDILLTKV-GA -ENVNDRLRSYGIREITVNRTCQHLIMKFSQITKDQSTPRAMNRLLEMIYKK--------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=A0A4R6Q7A1_9FIRM ------------IKKIPGRSGLYYKNLVTNEVL-AYNETEEFHPASMIKLPVFMAISKMVA -EGKARWNDKIKITYDVRVPSCGAFNAFTDEPVDVKTLCNLMITISDNTAANVLISHF-GI -DRLNGEFAATGLEKTHLERLFYDDEMQ-AKGFNNKAVPAELGGLLEKLHRKTFVNEKVSD -EVLAVLYDQQD-KCYIPEWFEDECPVANKTGGAR-GILGDEALVQTD--KPFVLVMMFNE -TV--TPEAAEFMRHAGKQLY--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=A0A5J6H197_9ACTN ----------------------------GGREV-GVGADDPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRHPDGECHAVAVFART -HA-LAASRPTVDAAVGRAA---- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. WAC00469 TaxID=2487415 RepID=A0A429NCM4_9ACTN --------IAADWAVLGMRGSFLARRLDTGEQL-GFDIDDPVPLASVVKVPFALVVLDRIA -AGLLDAAQPVTVDPATSSVGSTGLAARHPATVAVGDLLALMLAVSDNAAADALFDLV-PP -EETDARLREWGCTDIRVRHRMQRMYETLDPAHANAGTARGLVDLLQRVWQDEIARPAATA -ELRRLMAAQVF-THRLAGDLRDTIRVSGKTGTFLH-LRHDIGVVEADSGHRVAMAALTRS -DRALAPDIDAAIAAAARQAF--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium algidicarnis TaxID=37659 RepID=UPI0004966C3D ------KEIKKYLESRIGDYSFYFEDLDGGYIY-GYNENVPMISAGCIKLPIAMAILKESE -IGNISLNDKLSVSIDDKVSGNGIIHEFEEKEYSLIELLIAMLIQSDNTATNKLVDLV-GM -SKINSIFKEMDLKSTKLNRRVEKEK-DVDSRIQNITSSYDLCLCWKHLYNSSYLNKKNSS -WVIRIMKKQQM-KNKLAFYMGEEIKIANKTGDLS-GVENDTSFIQVPKGN-FAFTMMSKG -VPND-VYGIVTLAKSGKMMW--- ->[subseq from] serine hydrolase n=1 Tax=Clostridium mediterraneense TaxID=1805472 RepID=UPI00082E4587 ------KEIQDYLRSRMGNYSFFFEDLRSGYVF-GYNENVKMTAAGCMKLPIAIALIKKEE -DGELSFLDKVKIEKEDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDIL-GI -DKINETIKLLGLKNTVLNRKVTDE-RNKDDDIENITTAYDLGQLWKILNNSTYLNENNST -MLIDILTRQQK-KNKLALYLQDDFKISSKTGDKK-GVENDTELIKLNKGT-FSFTVMSNN -IPNS-VYGTVTLAKSGKMMWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. SLBN-134 TaxID=1081603 RepID=A0A542WM24_9ACTN ----------------------------GGHEV-AVGADDAVVIASLFKMLLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLHRV-GL -DTVRLLAKELGLERTRVVGGPRDLLEVLDPRRTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARFPDGECYAIAVFART -HDASRATVDAAIGRAAGMA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora aurantiaca TaxID=47850 RepID=A0A1C6T291_9ACTN ----VAERIGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMVVLEFARQAA -AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -ERARRIDVDLAMGEAARTAVD-- ->[subseq from] serine hydrolase n=1 Tax=Gordonia terrae TaxID=2055 RepID=UPI0013F5F719 --------------DAGCSGCVHVRTIGTPVEY-CQHADTPVVLASVYKLAVLVSLCRMAD -RGDIDLTASITVDPTRWAQGPTGLALFSDPVISWRDLATSMMTVSDNVAADVILAHI-GL -PQIRDDLVDLGLTHTRIVGGVAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASAASCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AVRNEIGVIEFPGEVPIAVAVFTMS -ARSELPEVDRAIGEVTRVIVT-- ->[subseq from] HTH lysR-type domain-containing protein n=1 Tax=Propionibacteriaceae bacterium NML 130396 TaxID=2016507 RepID=A0A255HBS8_9ACTN -------RILDLWAGVEIEGAVHVRDLDSAAEL-GIDSDESWPLASVAKVPLAVALHRAAE -RGLVDLDQPRVLRPDGRTRTTGISAMSDSVTMSLRDAAYLALTISDNAAADAIWDAI-GA -DRIRASLREVEPGEVWLGEPTRDLYDAVDGPRACRATPRGATRLLARIWADEAASAPGCA -HLRDLMQRQVW-THRLASGFPEDIVVAGKTGTVQD-HRHEIGVVTYPDGSRYAVAVFSRR -RDRAAHHRDWAIGETARLAVN-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis keratiniphila subsp. keratiniphila TaxID=227715 RepID=A0A1W2LT90_9PSEU ---EVTEKINERAKEVGVRVRLHAAEIDGARQI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLTLDRV-GK -EATEKTLRDLGFEHTTVSQDCGEVLRALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA -DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Nocardioides luteus TaxID=1844 RepID=A0A1J4N689_9ACTN -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPIAVHTDFDSAVAGARWEAIGSALPLADLVRRSLTVSGNLAVNLVLERV-GL -EEVAAVLADAGVTMTTVARGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA -ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGDPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI000563D612 ---TTDEQLRAVFADAGCRGWVRAERIDGIGTAvDYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DALTRVIDDLELEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASTAQCL -YMKAVLAQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID8499 TaxID=2706106 RepID=A0A6B3E393_9ACTN -------------------------------EV-ALGADEPVVIASIFKVLLVLEFARQAV -AGQLDPRERVRVGAADRLGGWGTAGCLDDVELSLRDLAHFALSVSDNTAADLLLAHV-GL -DTVRLLAKELGLERTRIAGGPRALLEVLDPRRTTASTPREITRLLRLVWSDAAGPPDACA -LVRELMGRQVF-RHRLASGFPDGVTVAAKTGTLP-GLHMEAGVVRYPDGAHYAVAAFART -RDPASAAVDAALGRAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Pseudonocardia sp. HH130630-07 TaxID=1690815 RepID=A0A1B1ZKC8_9PSEU ------------------------------DEV-AVGADVPVVMASVYKLLVLVGYCRAVD -DGRLDPREPVVVGPGWRTPPTGVSALADPVTMSRRDLVRSMITVSDNAAADVVHAEV-GR -DRVAALPGELGLTGTRVRGGTAEVFAALSPAFGSSTTAADSTSLLARLWRGELASAAGTA -FAREVLSGQIW-PHRLRAGFPAAAAVAGKTGTVG-AVRNEVGVVTYPGEHPVAVAVFTHA -ARSDVPRADAAIGAAARVAVN-- ->[subseq from] Serine hydrolase n=1 Tax=Rhodohalobacter sp. SW132 TaxID=2293433 RepID=A0A371QK48_9BACT -----EDEIRERIDAFQGDAGLYVYHLDSGFEF-TIHPDTVFPTASTVKIPIMIGLFDKIE -RGEIEYTQVFQYSDEHADPGDDIINQLPEGTVELNRLIHLMMSTSNNTASLWNQYIAGTG -TEINNLMDQKGFSDTKVNSRTPGREQIWEEYGWGHSTPRELARLLLNIYKGEMISPGASE -KMYRIMGRNFW-DGEALSQIPPYVNVASKNGSVAR-SKSEVLLVNAPSGD-YLFALMTKN -QEEYDNEGFVLLREISAILYNHf ->[subseq from] Serine hydrolase n=1 Tax=Tsukamurella sputi TaxID=2591848 RepID=A0A5C5RMC1_9ACTN ----AAARIDAAFADAGCNGWVHARVIGHPAEL-SVGGAQPVVPASIYKVLLLVAAARAFD -TGRLDPRTRVTVDPGSATPPTGIAALSDPVEMSLRDLLRSMIAVSDNAAAGELMRRV-GL -DAVQETARDLGLHGTRIVGGDAEIHAAYDPSFGSATTAADMTALLAAIWTDTAASPAQCA -FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRSEVAVVAYPGEHPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Woykebacteria bacterium RIFCSPHIGHO2_02_FULL_43_16b TaxID=1802601 RepID=A0A1G1WQA8_9BACT ------------------------------------------------------------- ---------------------------------------YNMITVSDNEDAIYLSEMV-GW -NTIQKVMNRYGLAKTTLGSPP-------------MSTPMDIATYLELLHDKKLVNEAYSE -VMYRTLLEQKV-NDRIPRDLPKGTKVAHKTGELDD-VRHDVGIVETPNNT-YLIVLMSKN -ME-NEVRVKNIMADISKEVFDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora halophytica TaxID=47864 RepID=A0A1C5HC10_9ACTN ----VQQRIGQLFAQAGGSLHVVPVDGPHEQEV-ALDADRRTVIASVFKILLVLEFARQVA -AGQLDPTERVLVTAGDRLGGWGVAGCADDVEVSLRDLAYFAMSVSDNTAADLLLRRV-GA -DVLPMLAAELELGRTRLRGGPRHLVEVFDPERTSSSTARDLTRLLTLIWCDRAGPAVACA -TVRELMSRQLV-RTRLASGFPPGVRVVSKTGTLP-GLYLDAGVAEYPDGARYAMAVLVRA -EHARRIDVDLAMGEAARIAVQ-- ->[subseq from] Uncharacterized protein n=3 Tax=Candidatus Shapirobacteria TaxID=1752721 RepID=A0A2M7BCL8_9BACT -----KKSIESILLPLRGKYGIFYEDIGSKNSF-GINEKEVFTAASLIKMPVLITLYREAE -IGNINLDEVYKLQASDKREGAGALQNKPGFEISYRKIAELMGEQSDNTAFNVVANKL-GT -EKIQNTINALGMKNTSYA--------------ENLTSPVEMGLLFRKLYLEKIISDKNRD -EILSFITDTIW-EDRIPVGVPEGINVSHKIGTEV-GVISDAGIVFGP--KPFILVIMSQE -VNE--IEARKALPEITKKIYE-- ->[subseq from] Beta-lactamase n=1 Tax=Clostridium chromiireducens TaxID=225345 RepID=A0A1V4I9M5_9CLOT -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSVIKYIQ -DEKGSFLDRVKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIEIV-GI -DNINEDIIAQGLKNTKLNRKTSDE-RATSSGIENITSALDLARIWKHLYNSSYLNEKNST -MLIDILQRQQM-KNKLALYIPDDFEISSKTGDKSS-VENDTALIHTQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium estertheticum TaxID=238834 RepID=UPI0013E92FB0 --------IKKYLETREGTYSFYFEEINSGYLY-GLNENKEMVSAGCIKLPLAMVLLKEVE -DGKIDLQSKIKIEAEDKTHSNGIIHELSGKEYSLYDLLIAMLIQSDNTAANKIIEIL-SM -QRIDELFVGMGLKNTKLKRITTDAKLE-QDELENITSSFDLSKCFKLLYLKQYLNEENSN -LLLRILKKQQV-TNKLPFYVPKQIQIANKGGSLDT-VENDTSIIMIEKGN-FLFTVMANN -LP-NNVYGITTISRVGKMMWD-- ->[subseq from] Putative beta-lactamase n=1 Tax=Scytonema sp. HK-05 TaxID=1137095 RepID=A0A1Z4IZ77_9CYAN ----LQRKLEAVAKGSDGRVGICAEEIKSGAIA-CVNGDQRFSLQSVMKLVVGAAAMDAID -RGQMRLEDVITVRKNDLSLVQPIADLVAQRGTTVADLISRAIIESDSAATDLLFAQVGGA -EGIQTFLKTKKISGLRVDRDEKHLQTAYLKDERDTATPRGMVTFLSALARGK-------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Caulobacter sp. X TaxID=2048901 RepID=A0A2G5R121_9CAUL ---DLRKSIDPIAARAPGVLGVAAEDLGTRQLW-DFNGDHPFMLGAAARIPILAAVLADQA -AGRLDPNETITVRDVDLSPPSAVADAWPGRRYTVAAL-EALARAGDNTALDLLAKRIGGP -GAVNGWLGVRQLTGISVDRYRRQVETRRAADDRDTATPVGLVRLLEAFNTREAFASADPR -LLTG----D--DPGYLATGLPKGAKIWQAAGANRTPESHAVALIELEDGRRIALAVFLSG -STADTAAREAIIAETGRTVLKSf ->[subseq from] Beta-lactamase class A n=2 Tax=Bacillaceae TaxID=186817 RepID=A0A660BV67_BACCI ---KLSKLINKIVQEYEGHFGIAMEW--RGQGF-FLNENDVFPSASLIKLPVMVESFMQSS -GGTLALEDLVEVRSLLRTGGAGIVQYMSPQSLSIRDLLTLMMIVSDNMATNYLIERL-GM -DNVNRRCQQLGMSSTVLQRKMMDREA-RKRKIENYTSPHDILRCLKAIYNDRNQSGK--- ----TILYHQQL-LDKLPRGENSGIRIANKTGELDK-VEHDCAIIEHEDE-IIFIAILTDQ -LTAN-QKGKELIQLIGASIFE-- ->[subseq from] Cell wall-binding repeat protein n=1 Tax=Marvinbryantia formatexigens DSM 14469 TaxID=478749 RepID=C6LJ76_9FIRM ------------------------------------------------------------- ---------------------------------SVKNTISSMITVSDNTAFNTIVRTI-GT -SYINTWCKANGYTGTNQGHGLSPSSNLSNGTGSNVTTAADCGKLLESIYRGTCVSKSASK -KMLGYLKKQTR-RSKIPAGVPSGVTVANKTGETDD-TTHDAAIVYSKGA-DYILVVMGDT -PG-SGWASTANITKFSKIVYNYf ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus timonensis TaxID=1926285 RepID=UPI0009B9FEFD ---------------------------AGDEEI-AFHHKEEVRAASIIKLFILAAAYYEEE -KGNLDLSRQVCISSSDMAGGAGVIPYLSDKQYTYQQLLELMIIVSDNTATNVLIDYI-GL -DNIHVFIQTIGCKQTTLERKLMD-EEAIKHGLENKTTCYDVMHLLDFFTENDILSSYAQE -KMLTILGNQQL-NNKLTAYTSHTIRAFHKTGELNR-AEHDAAIFQTADK--LLKAVVLTE -GWTNNGHGQQFHQKTGLHIYH-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E43337 ------------------------------CEV-GIGADDPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAAELGLQRTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS -FVRDLMLRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAVAVFART -HA-LAASRPTVDAAAGRA----- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis thermalba TaxID=944492 RepID=UPI000E267D1A -------------------------------ES-GLGPDEPVVLASVVKVPLVLELARQVA -AGQLDPADRLRVGAADRLGGTGTAGCADDVELSLRDAAFFALSVSDNTAADLLFDRV-GL -DNVRSLLRELGLARTRVIGSPRDVVAALDPLRTSATTPRDMTTLLAAIAGDTAGPPEACR -WVRQLMGQQVN-WHRLTAAFPPQVRVWGKTGSLL-AVRNEISVAEYPDGARYAVAVFTRA -PTSRLPDVDHAVGAAARAAIE-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. BL1 TaxID=2478709 RepID=UPI000EF595EA ----VAERIGEIFGRAGVRGCLHVVDVDAGGDV-ALRADEQIVIASIFKIMLVLEFARQAA -AGQLDPTERVVVGPADRLGGWGVAGCADDVEISLRDLAYLAMSVSDNTAADLLLRRV-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -QRARRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinus TaxID=67345 RepID=UPI0006EB8F13 ----------------------------GGREV-GVGADDPVVIASIFKVLLVLEFARQTA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRHPDGECHAVAVFART -HA-LAASRPTVDAAVGRAA---- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7CEB8_9BACT ---DLAKRLNELCDAEKFQASWYLKDLGTGASA-DRRGAVPVPSASTRKISIMMAALAAVH -AGKLSLDQKVTIDARYQDNDSGTFQHLTPGFITLRDALVMMIIVSDNTCTGTVVDLV-GL -ANVQRYSESVGLTGTVHRYGIPKLAPDHSLDRVTTTTPNDQGLLLALILQGTQCTTALCR -LGLDILSLQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKADRPLCVLTAYTVD -VPETFAAAYRLIGR--------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=UPI0004C40E6F ---------------------------GGGREI-GVRADEQVVIASIFKVLLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRLLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMAQQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -VEPRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Ruminiclostridium sufflavum DSM 19573 TaxID=1121337 RepID=A0A318XIP7_9FIRM --dELEKLISDYTSKLPGKYGVTFIDLATGETV-NINDKTEYIAASTSKLPINVLLYKKIE -AGEINPEDKLVYKQEDLEYTGSIIGTPFGTEYSVRETSKLSIQKSDNCGVNMLIRLL-DI -ENVRNYIDEVGGQVHY--------------GKTHRSCPYDMAQIAQDLYKLYLNNEEVYG -ELLSYMETTDW-HDRIDAKLPKEVKVAHKIGNQTT-TRNDVGIVFAT--HPYVLSVMNDN -VN--IDAATKAIAELSKKIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. SLBN-169 TaxID=1571486 RepID=A0A542T5D7_9ACTN -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPITVHPDSAVVGSRFEWAAVGSPLRLGDLVRRSLTVSGNLAVNLVLERV-GL -EEVATVLADAGVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKLLTKLASGRLLSPESTA -ELEGTLVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9XXJ1_9ACTN --------------------------VAGGREV-AVGADEQVVIASIFKILLVLEFARQVT -AGQLDPTERVLVTGADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLARTRIVGGPRQLVEVFDPERTTSSTARDITGLLGLIWRDEAGPAAACA -MVRNWMARQLF-WTRLATGFPPGVRVAGKTGTLP-GLHMEAGVAEYPDGGRYAIAVFART -AQTRRIDVDLAMGEAARTAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Kitasatospora sp. MMS16-BH015 TaxID=2018025 RepID=A0A2H5B9J2_9ACTN -----TDDIREIFERAGCTGVLCVRSLQDDAEV-ALGADGPVVLASVSKVQIALEAETWFA -EGRLDPREPVRLTGADRTPGPVGTSLFSDEAVSWRDLVVLMLTISDNLATDALLGRF-GV -EAVNRTAARLGLSATVLDSDLRTMLDALDPERGTRSTPREMTELLRLIWTDRAGPAEACA -RVRTVMARQLT-RHRIASAFRPPVQVAAKSGSLFGVVRNEIGVVTHPDGGQYAAAVFTRA -RPSDEAAVNRAIGAVTALAV--- ->[subseq from] serine hydrolase n=1 Tax=unclassified Clostridiales (miscellaneous) TaxID=39779 RepID=UPI0009E982BC ---SLESRINAEIYNFSGMIGLYANDF-KGNII-EINSRDKFETASTIKVFILAELYKQIY -EKKISPNKILKYDKENYVIGSGILRDLDYSVMTAKSFAILMIIISDNIATNILIDLL-GI -DNINNTCQDLGFKDTILHNKID-FEK---HSKLGTTTPKDYGKFFELLYKKELWSKEISE -EMIGIFKNQHY-NTILTRDLPPYISIASKSGSMD-ACRNDGGIVYTPYGG-YVISIFTKE -FVDNDHESYRFGGKISRLMFDQ- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis rhizosphaerae TaxID=2053003 RepID=A0A558BBW7_9PSEU ------------FVAAGVRGWVHARCLACDGEA-GLAPDEPVVLASVVKVPLVLEFARQVA -AGQLDPADRVRATAADRLGGTGSAGCLDDVEYSLRDAAFLALTVSDNTAADLLFERV-GV -DNVRSLLRELGLTATRITGPPRHIVQALDPLRTTASTARDMTALLALVARDLAGPPEACR -WLRELMGQQVN-WHRLAAAFPPEVGVWGKTGSLP-AIRNEIGVVEYPAGTCYAVAVFTRA -EVSRQPALDHVIGEAAREA---- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. Cs-700 TaxID=2589818 RepID=UPI0014091A0C ----VKEKILECFHGLEGNQSIYVST-PDG-EI-ALHSDQPISSASIIKIAILIEALRQVD -VEQLSIDQVVQIDNVNYVGGAGVINHLSRDHWKLADLLKLMIISSDNTATNQLIDLV-GE -HNINHTMKAAGAFHSKLMRRMMDRNA-LKSGLDNMVSGKDTYLLLREFVTQHLLSQSSME -WGVEVLLQQQF-KDKFPSKISKENLLAHKTGELI-GVEHDAGILFTSNG-PVVYAFLTAG -LL-ENRYGREAIANAGRLLYDFy ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. RB5 TaxID=2585196 RepID=UPI0012967F6C ---SAAEEIRRVFEAVGADGQVHAVPIGSTSEV-DLRAGEPAVIASLFKVPLVLEFARQCA -AGQLDPRERVRVTAEHRLGGWGTGGCADDVELSLRDLAFFALSITDNAAADLLLDRV-GL -DTVRLLAQELGLTSMRLTGGSREVLRALDPARTNSAAPRDITRLLRLVWRDEAGTAQACA -VVRDLMGHQVF-RHRLPTGFPADVRIAAKTGTLP-GLHIEAGVIQPPGPDAYVVAVFART -RRARLPEVDAAIGTAARLAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. San01 TaxID=2494256 RepID=A0A437PM02_9ACTN ----VIAKINDRAKQAGVRVRLHAAEIDGTRRI-GVDEHSPVVTASVFKVPIALELARQAA -EGGLDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK -EKTEKSLRRLGFENTTVPQDCGEVLGALRPEHTCATTAEEITRLLALIWRDEAAAPTACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Proteobacteria bacterium TaxID=1977087 RepID=A0A2E5Q7A5_9PROT ----LENDLNQLCDEQPFHTGWYVRNLYTGDNL-QRHGXVVVPSASTRKIAXMMAALKAVS -EGGLALDQPVTMSAGYQDNDSGCFQHQPGFTIQLRDALVMMIIVSDNTCTGVVADLV-GL -ESINSXCQSIGMTGTVHRYGIPGMAGYLPAAQTNATTPADVAHLLDLILRGSGCRPESCQ -LAIDILSWQRL-RNRIPARLPLGTRVAHKTGTTAK-NYNDAGIVYFEDTPLFIISSYTDA -VEAE------------------- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00142F88E7 -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCT -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Uncharacterized protein n=1 Tax=Amycolatopsis japonica TaxID=208439 RepID=A0A075UVJ6_9PSEU ---QVTETITERAKEVGVRVRLHAAEIDGSRRI-GVDEHAPVVTASVFKVPIALELAKQGA -EGALDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -EATEKTLRDLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGLIWRDEAAAPAACA -DVRRWMDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=Virgibacillus sp. YIM 98842 TaxID=2663533 RepID=UPI0013DC1933 ----LKKEVQRIEADTDGTIGVFI---DTGEGIiNMNEKEVMSSASVIKVPILAEAIRQAE -RGDLIWEDEVLVQESDAVGGSGVIRDMDLPVMTVRELAELMMTVSDNTATNMIAERV-GF -DQVNWTCIELGCEDTVMQNSIYTSMPQ-DRGPHNYTNAKDMATVVSGVINEDIFSSEGKE -EFLRIMREVPD--GRLTGYKDGDIQTGRKGGSTAPRVLHDVAVFTLGDKE-IYAAVLTHN -VVPN--TATPTISEIGKEIMDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Jiangella alkaliphila TaxID=419479 RepID=A0A1H2JP24_9ACTN ----------------------HAVDVGSGVEV-GVEPDAPVVTASVFKVSVLVELCRQFA -TGEREPADRLRVPAGARTLGPTGLSVMLDDALSLRDVAYLMMSVSDNHATDALMALL-GR -DRINALMVELGLPGTVLEEDCAGLFRVLDPRTTNRSTPRETTTLLRRIWAADGLPAAAGE -EIRRIMALQVW-PHRLTSGFQDDVKVSGKTGTLSH-VRNEVGVVEYPDGATFAVAVFLRL -PGGENPAADAVIGTAARIAVDH- ->[subseq from] serine hydrolase n=1 Tax=Aestuariivita boseongensis TaxID=1470562 RepID=UPI000A4713E1 ------------------------------------------------------------- -----------------------------------------------------------GP -AAVTEYLRRLRITDISVDRTTGEIIGDFEADPRDQSTPLAMLQLLLAIDNGTATSAESRD -FLIDVMSRTRTGAGRLKGLLPRGTPVANKTGTIG-GVANDVGYITLPDGRRFAIAVFTKS -SETSEADRDRAIAEVARSLFDYf ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000362CD43 -------------DRVSGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDQDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ322 TaxID=2572904 RepID=A0A560AX35_9ACTN ---------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9WST4_9ACTN ----VEERIESIFAAVGVTASLHVVDLDGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCTDDAEVSLRDLAYFAISVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMAQQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EEPRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. ADI98-10 TaxID=1522763 RepID=A0A3N6IXM6_9ACTN -----------------------------GGEV-AVGADEPVVIASVFKVLLVLEFARQVA -AGQLDPRERVRVGAPDRLGGWGTAGCADDVELSLRDLAFFAMSVSDNSAADLLLARV-GL -DTVRLLAGELGLDRTRIVGGPRDVLDVLDPLRTNASTPREITRLLRLVWSDEAGPPEACS -QVRELMGRQVF-RHRLVSGFPDEVAVAAKTGTLP-GLHMEAGVVRYPDGGHYAVAVFART -REASRTAVDAALGATARIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces alni TaxID=380248 RepID=A0A1I2H1Y1_9ACTN --------------------------------I-GYEPDQLVCTASVHKVCVLLTAHRLAA -EGRLRLTERIDCRAAGRTVGSTGLSAMLDDVMSARDLAYLMMAVSDNAAADLLLERV-GL -DEVNRTTRLLGLERTLAVENFAAAQAALDPARSNRSTPRELTRLLGALWHDELCSPEHGE -AMRRLMSLQVW-PHRLASGFPDDVGLAGKTGTLPT-LRAEVGVVEYPDGGRYAVAVFTRA -ADHVLPAADSVIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=UPI00105BD603 ------------IKKIPGRSGLYYKNLVTNEVL-AYNETEEFHPASMIKLPVFMAISKMVA -EGKARWNDKIKITYDVRVPSCGAFNAFTDEPVDVKTLCNLMITISDNTAANVLISHF-GI -DRLNGEFAATGLEKTHLERLFYDDEMQ-AKGFNNKAVPAELGGLLEKLHRKTFVNEKVSD -EVLAVLYDQQD-KCYIPEWFEDECPVANKTGGAR-GILGDEALVQTD--KPFVLVMMFNE -TV--TPEAAEFMRHAGKQLY--- ->[subseq from] serine hydrolase n=1 Tax=Silvibacterium bohemicum TaxID=1577686 RepID=UPI000678C4D4 --qALQAKLSVLAAGHHGKVALYAEDLVTGKTV-ALNADTPVQTASVIKLTVLYEALEQVR -DGKVHFDDKLTLTHGDQVAGSGVLAFFDTPQLTFKDALTLMIILSDNTATNLAIDHL-GL -KSIDDQIVALGLKDTWLYKKIYLPSSDQKTFGLGKTTAYEMATVMKRLVTCDL------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442) TaxID=644283 RepID=D9TD39_MICAI -----AERIGEIFGPAGVRGCLHVVDVDAGGEV-ALRADEQIVIASVFKIMVVLEFARQAA -AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -ERARRIDVDLAMGEAARTAVD-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacillus circulans TaxID=1397 RepID=A0A0J1I965_BACCI ---KLSKLINKIVQEYEGHFGIAMEW--RGQGF-FLNENDVFPSASLIKLPVMVESFMQSS -GGTLALEDLVEVRSLLRTGGAGIVQYMSPQSLSIRDLLTLMMIVSDNMATNYLIERL-GM -DNVNRRCQQLGMSSTVLQRKMMDREA-RKRKIENYTSPHDILRCLKAIYNDRN------Q -SGKTILYHQQL-LDKLPYYCGSGIRIANKTGELDK-VEHDCAIIEHEDE-IIFIAILTDQ -LTAN-QKGKELIQLIGASIFE-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00037AFF2F -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCT -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=A0A1G9HDR3_9ACTN -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPIGVHPDSAVDGSRFEWAAVGSPLPLGDLVRRSLTVSGNLAVNLVLERV-GL -EEVAAVLADAGVTMTTVLRGIEDAPA-REAGLQNLATANDMGKLLTKLASGRLLSPESTA -ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=UPI0009887920 -----------------------------EHRI-AFNEMKQLRAASIIKLFILAAAYYEEE -RGNVNLSKQVNIPGLDLAGGSGIVSYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL -DSIQTFIEKIHCENTKLERKLMD-EEAIKLGLENVTTCYDVMLLLDLFTENNILPEHRRQ -QILTVLENQQF-NSKLTASYDSDIRTFHKTGELT-GAEHDAAIFQTDDK--LLKAVMLTE -GWTNNGEGQQFHQAAGAHIYHY- ->[subseq from] Beta-lactamase n=2 Tax=Mycobacteriaceae TaxID=1762 RepID=A0A0E3XSW7_MYCCH -------QIRAVFLDAGCRGTLRAERVGTLTPVvDVDGDRPAVSASVYKIFVLIAAARAFD -SRTLDPDATVRVVPADCTPGPTGISTFSNPVLSWLDLARLMITHSDNTAADVLLAAV-GL -DTVNEITEELGLGSTRIIGGTSALQQAFDPAYTTSTSAVDTARALSAIWTGAAASPQSSE -MMRHILAQQIW-QHRIRSAFPRDVIVAGKTGTIGP-IRNEVAVIVFPGEPPMTVSVFTRA -ARADLPNVDRAIGEAARIAIT-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7DMA2_9BACT -----VADLDKLCDELPFQTGWYLKDLRRGETA-RRNGDVVVPSASTRKIAIMMTALKAVH -DGKLALDQPVTIQVKYQNNDSGCFQYQPGFTIQLRDALVMMIIVSDNTCTGMVVDLV-GL -DAINALSHAAGMRGTTHRYGIPGMAGYRPASETNATTPTDVGLLLEHILRGSGCTPVLCQ -LGLDILSWQRL-RNRLPARLPLGTKVAHKTGTTAR-NYNDAGIIYQGNQPLFILSAYTDD -VPPEHTAAHTLIARMSRLCYD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NK15_9ACTN ---------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVVVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces lividans TK24 TaxID=457428 RepID=A0A076MHI3_STRLI ------------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLVKELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTAARIAVD-- ->[subseq from] Serine hydrolase n=2 Tax=Couchioplanes caeruleus TaxID=56438 RepID=A0A1K0GDH9_9ACTN ---------------------LHARDIDTGRAM-GCRAGEPVVLSSVFKILLALEFARQVA -SGALDPAERVTVGGGDRLGGWGTGGCADDIELSLRDLAYFTMSVSDNTAADVLLRRV-GP -DLLPLLAAELGLTRTRVVGGPREMLEVFDPQRTTSSTPEEITRLLQLVWRDAAGTPEACA -MVRDLMARQMF-WTRLAAAFPAGVRVSGKTGTLP-GLHMEAGVAEYPDGGRYALAVFVRT -HRTSRMDVDRLLGRAAAAAVRH- ->[subseq from] Beta-lactamase class A n=1 Tax=Gordonia sp. v-85 TaxID=1761786 RepID=A0A1C4BQM1_9ACTN -----DRTVHETFADAGCSGCVHVRTIGTPVEY-CHDADTPVVLASVYKLAVLVSLCRMAD -RGDIDLTASITVDPTRRAHGPTGLALFSDPVISWRDLATSMMTVSDNVAADVILAHI-GL -PQIHDDLVDLGLTHTRIIGGIAESHAAYDAAYSSAATPRDCTTLLDAIWTDRAASATSCE -FIRQTMRKQVF-TSRLASGFPRRVSVAGKTGTLV-AIRNEIGVIEFPGEVPIAVAVFTMS -ARSELPEVDRAIGEVARVIVT-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535JCH0_9CHLR ---DLVRQLDGLIASFPGGAGIWIGDPTVATPIfTHDPEEHVITASLYKLGVLAEAERRVD -TGELRYDDIVTIESDDITVDGSF--EDAGTQLTLDEALEAMITISDNGSALALWRIL-GG -ENIDATLEKAGVKDFHVAFDESE---------DNWATPHAIGTFFTLLAKRQLISAAASG -RMLERLERQQI-NDRLPAQLPADTVIAHKTGNLG-GLAHDAGIIYTKTGPRVVVAMTWNG -LDED---AANFISSIGSLVYS-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora pisi TaxID=589240 RepID=UPI000EB32A00 ------ERINRIFTVVGVDAQLHVTDIDSGAEV-AIRADEQVVLASVFKILLVLEFARQTA -AGQLDPTERVVVRAEDRLGGWGTAGCADDIELSLRDLAYFAMSVTDNSAADLLLRRI-GP -DLLPLLAAELGLTRTRIVGGPRQLLEVLDPERTTSSTPREITRLLGLIWREEAGPPPTGA -LVRDLMARQVF-WTRIASGFPPPVRVSAKTGTLP-GLHMEAGVAEYPDGGRYAIAIFARM -RQLDTRRVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Tsukamurella pulmonis TaxID=47312 RepID=UPI000798021E --------IDGVFADAGCNGWLHARVIGHPAAL-SVGGEQPVVPASVYKVVLLVAAARAID -AGRLDPRARVTVDPASATPPTGIAALTDPVEMSVRDLLRSMIAVSDNAAAGELMRLV-GL -EAVQESARTLGLSGTRIVGGDAEIHAAYDPSFGSATTAEDMTALLAAIWTDTAASPAQCA -FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVSVVTYPGEHPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JV13_9ACTN ------ERINRIFTVVGVDAQLHVTDIDSGAEV-AIRADEQVVLASVFKILLVLEFARQTA -AGQLDPTERVVVRAEDRLGGWGTAGCADDIELSLRDLAYFAMSVTDNSAADLLLRRI-GP -DLLPLLAAELGLTRTRIVGGPRQLLEVLDPERTTSSTPREITRLLGLIWREEAGPPPTGA -LVRDLMARQVF-WTRIASGFPPPVRVSAKTGTLP-GLHMEAGVAEYPDGGRYAIAIFARM -RQLDTRRVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A386WQ40_9ACTN ------ERVAEIFGRAGLRGCLHVVDVDAGGDV-ALRADEQIVIASIFKIMLVLEFARQAA -AGQLDPTERVVVGPADRLGGWGVAGCADDVEISLRDLAYLAMSVSDNTAADLLLRRV-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -QRARRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Flavobacterium sp. Leaf82 TaxID=1736238 RepID=A0A0Q4SJI7_9FLAO --dKMKTEILEIIKDKKFDIGISVRNSKGVEIF-GHKSNEKYKMYSVSKFFLALKVLHLVD -KKTLLLNQNVSFAKSDLKAFSPLRDSNPEGIITLEKALYYIVNQSDNNVFDKLVDLSGGI -ESLNSYISSFTKNKN--SFFMSALYRDKEGTINNVVTPGFSSLLLYKLMKNKIISIESKN -ILLPLLETSIN-NKRIQALVPKNLKSFHKGGTSDRVASNDIGIVYLNEKDFFTIAVFISN -SLEDDAVNDAVTAKITEIT---- ->[subseq from] serine hydrolase n=1 Tax=Clostridium polynesiense TaxID=1325933 RepID=UPI0006932932 ---EMENNIKNYMGADLNSLGFIYYDTSTGEKI-SINENKIFLAASTVKVQLNMIAYDWAE -KGRLSLDDSIKYKESDNEDGTGILQNQDKSQFKIQELLDYSIIYSDNIATNMLFRTLGGY -KKVRSMVNK----KFGI-------NMDTS---GNYITPQGEFTILKYLYDNRT--NSNYA -HLIDVMKGTVF-HDRIDKYIPQDI-SAHKTGEYDY-YVNDVGIIFTEN--PYILVVYTYN -IE----NAHEKIAEISKMIYNY- ->[subseq from] Uncharacterized protein n=2 Tax=Kocuria polaris TaxID=136273 RepID=A0A0W8INN5_9MICC -----AQRLAELAEEVPGELGVVLLDPEGGEVA-ARNADRPFTSASLYKLFLAHAVLDEVD -RGTLSLSDTL-----------------PELGLTVEQALDVMISWSDNASGAALGRRL-GW -QEVEAFAHEQGFGATTFDPGTGSE-----DVVAMTTTPADVADLLDRLRRGELLSGPSTE -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLQD-VSHDAGILELGGR-DYVVAVLTDG -WS-DYEESAPWFGEAGR------ ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. RP3T TaxID=2135446 RepID=A0A2T3VFA2_9ACTN ------QRVGEIFGRAGLSGCLHVADVDDSREV-ALHADEQIVIASVFKILLVLEFARQVA -AGQLDPTERVLVGAADRLGGWGVAGCADDVEMSLRDLAYLAMSVSDNAAAELLLRRV-GP -DVPSMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAAACA -TVRELMGRQLF-WTRLTAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGARYAIAVLVRT -DQTRRIDVDLAMGEAARAAVE-- ->[subseq from] Uncharacterized protein n=2 Tax=Fusobacterium varium TaxID=856 RepID=A0A250LTC3_FUSVA --eKFENKLLKILKKYDKKYGIIIKNLGNDFFI-KVGNMEQYQAASLIKLTILYELFNNPK ----YNLDEEMKITSTDKVAGYGIVQYHENIKFTLRDLAILMIILSDNTATNMLIDIC-GM -DSINFTIKKLGLKNTILQRKMMDSKSK-NIGLDNYTSPNDMMKLLEVLNEN--------E -EIISIMKKQLC-NNKIPYFFEEKIDFAHKTGDLPQ-IEHDIGILSIGDQK-IIIVIMTKN -FKN--KDEIELNNKVGELIY--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536KL65_9CHLR --dQLSADLQAIARTSGGRVGISLQELSGPRNL-SVNGGLNFVAASTYKLPLLMAEAQQIA -SGQVHRSDILCYAPSDAEDGW-FMDYQAGSCFTRDELALRTGRYSDNTAAHILVRYLGGP -DALNRYAKTIGMNNSAL--WVP-----------NTTTPDDLSQAMVSEALGRLGGAAAQA -WLYPILTRTTT-EQGIPAGLPGGTTVVHKTGTLD-ATENDAAYVRNG-RIAYVLSVTVDG -LD--VGAARSVIARISARIWQY- ->[subseq from] Uncharacterized protein n=5 Tax=Candidatus Beckwithbacteria TaxID=1752726 RepID=A0A2H0E2C1_9BACT -------TLENLIAGQPGDFGILVKSVNGQEEI-KLGENLVMTAASVIKLPVLIVYYQAVD -SGQLDPEAEYVLAEADRWKGTGSLQYQPAGTYTYRQVAQLAANQSDNMGAEVLIKKLGGY -AKTQQLVNKLGLTKINLKENE--------------ITAAEAGGLLLQLAQGKLLTPASRE -ELFRNLTKTVN-EDRLPAGVPDSVRVVHKFGSEA-GVVNDCGIVEA--GNPYVICVLTTA -VN--VGEVEPLLPQISAAVWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A562DCP6_MICEC ---------DARLAGVPGTVSVYAGRLDAAPTW-THAEHAPHYAASTMKVAVLAALYRAAE -AGALDPDTPVPVHNDFPSADGPRFWDRLDRTATLRWLAERMIVRSSNLATNILLGHV-GL -PAVAEVWALAGARHSVTGRGIEDYTAR-AAGITNLVTAADLAALLGALATGAIATPANCA -TMLDVLRAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT -DL-TDPDACRLLADVSARVWA-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00040D8E2D -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDVPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] serine hydrolase n=1 Tax=Phytoactinopolyspora halotolerans TaxID=1981512 RepID=UPI0013D35726 ----LQGILRDLAASSGGTWSFTVRE--DGRTVaTVDGDLEVRAASTIKVPLLILALQDVA -AGRRALDEMLPVPA-ERVGGAGVLKLMPSVRLPLVEALELMIGVSDNNAANMVIDML-GV -DEAAGRITALGATGTRLERRLYDVEA-MRAGRDNVTTADDQALFLDLL------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Chloroflexi bacterium 13_1_20CM_2_70_9 TaxID=1805058 RepID=A0A1Q8ADJ1_9CHLR ---ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD -AGELHYNDAVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG -ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD -RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD -APV--DDADAFISSIGAIVYS-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPLOWO2_01_FULL_39_10 TaxID=1798622 RepID=A0A1F6KL03_9BACT ----------DSTKDKTGFYSIYYKDLKTGGAF-GIDEKQIQTATSVNKIPIIASLYYLAE -APNLSLDEKVTITDTDVQDTGSIRYQKMPQVYSLRNLAKLALKDSDNTAAHVLSVRI-GQ -DVIQRLVDDWGLAQTDMV--------------NNQTTAYDMGKLFEMIYKGKITNEANTN -ELLEFMTDTDF-EDRLSKNLPENVKVYHKTGDGE-GSIHDVGIIDTGNN-VYFLGVMTSD -VGEAEQETKDTIAEISEKIYK-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ285 TaxID=2035250 RepID=A0A4Y9VN56_9ACTN ----VAERVGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMVVLEFARQAA -AGQLDPTERVLVGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRI-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRT -ERARRIDVDLAMGEAARTAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 04182 TaxID=2203198 RepID=A0A429FFY1_9PSEU ---EVSATITERAKEAGVRVRLHAAEIDGTRRF-GVDEHAPVVTASVFKVPIALELAKQGA -EGGLDLGERITVPPGHPTPPYGLATFRHEISMSWYDLAILMIGISDNVATDLILDRV-GK -ESTEKTLRGLGFEHTTVSQDCGEVLGALQPEHSCATTAEEITRLLGMIWRDEAASPTACA -DVRRWMELQVW-PHRLRSGFPDGILVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGVFTDA -IDSRVPERDALIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00036949AD -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDGAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535XF63_9CHLR --qDLVRQLDGLVSAFNGGVGLWISDPSLPTPLfTHGPDEHVVTASLYKLGVLAEAERRVE -AGELHYTDSVVIEPEDITTDGSF--EDAGTTLTLDDALEAMITISDNGTALALWHIL-GG -SNIDTTLTKLGM---------PDFHVAFDDSEDNWATPHALGTFFTLLAKRQLISPAASD -RMLARLERQQI-NNRLPAQLPQGVVVAHKTGNLA-GLTHDAGIIYTKSGPRIVVAMTWDA -GDDDA------------------ ->[subseq from] Serine hydrolase n=1 Tax=Weissella sp. 26KH-42 TaxID=2506420 RepID=A0A4P6YTH3_9LACT ---------------------------------------QNQIAASTIKIFIALACMDAAN -TKAMNLDKQHSLQQAEQVGGSGILMDKPGTRFTIRQLIELMLTESDNTATNILIDELGGF -TVLDKYLNTWGYRNTQIQRKLMDLSN-WNNGKSNRISADDACDVLVKLYQQKIVTTAQRD -WLLSLMLRTTN-RTKLPSKLPADVICYNKSGESTKGVENDLAIIQRGSQ-VFAVVGLSQY -YDPNQPASHQL------------ ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus kimchii TaxID=746691 RepID=UPI000378C3C5 -------------------VSVIL-KTNTGIIC--SKETKQMQSASIIKLFILASAYHFKE -IGKLSLTEKIRISTNGHVKGSGVISYLTDVPLTYQQLLELMIIVSDNTASNYLIDRL-GI -SNIQAFIESLGCQQTRLERKFMDVEAQ-KLGKENVTSALDVLRLFDIFTENNFLGENSQQ -HILHILNNQQF-NSKLTAFTEPLVTSYHKTGELK-GVEHDAAIFLQNNK--FLKVVVLTE -GWENNGDGQAFIASFGKVL---- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DBFB686 ---------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERILVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. Root369 TaxID=1736523 RepID=A0A0Q6Y011_9ACTN -------QLHAIALRSRTTVAADAGAEQGAREV-AVGADDPVVIASIFKVLMVLEFARQVV -AGQLDPRERVRVAAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAEELGLDRTRIVGGPRDLLEVLDPRHTTASTSREITRLLHLIWSDAAGPPEACA -FVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGECYAIAVFART -QDASRATVDAAIGQAAGIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinospica robiniae TaxID=304901 RepID=UPI0007C4F339 -----------IEAGYQGTLSVAEID--GAGRV-DVRAGEEAYAASTFKIAVGLELACQGA -AGELELTESMRLSPDDCTPGQGLCLFEYPVEISLRDLAVLMLTISDNTATDAVIRRL-GP -ERVGARLAALGLKQTDFTCTIHEHFDALPH-LVPYTTAGDMARLTGMIWRDEAGPAAACA -QVRVMMGKQWL-TRKIATGFGAGTSVAAKSGTAP-AISNDVGVVTYPDGQRYAVAAFTRA -LDTDPDAAARAIGAAARLAVEH- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Brevibacillus sp. BC25 TaxID=1144308 RepID=J2GJ80_9BACL --------------------------------------DELFIAESVIKVPIMAAVFTASE -LGHFRLDDQLVLRQEDLVGGSGILYGLSPGLLMIRDLVTLMIIQSDNTATNMLIDLV-GK -AQIDQTMIDLGMRQSCYSRKLMIYPLD--ITENNKITAGDVASMLGQLATGSYLSERACK -EMIAIMKKQQV-RNGLPSQLPNEWELPCKSGWDT-GRQHDVGLLYTNNR-CFSITALSKE -VT--AQSALNTLGLLGRAVYDY- ->[subseq from] serine hydrolase n=1 Tax=Rhodococcus fascians TaxID=1828 RepID=UPI0009B8FD11 ---TTDEQLRAVFADAGCRGWVRAERIDGIGTAvDYEGDDPVVAASVWKIVLLVAAARAFD -EGSLTATDSVRLVPAQCSPPTGISSFADPVTMSWRDIARSMITVSDNAAADALLGAV-GL -DALTRVIDDLELEHTRIVGGTKQLGDGFDPAYTSCTTPRDSNTVLRSIWLGTAASTAQCL -YMKAVLAQQVW-PHRIRSGIPPDVQVAGKTGTIGP-IRNEVAVVSFPGETPVAVSVFTRA -ARMDLPLVDQAIGHAARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI0013DB09D0 -----------------------------ADEV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLVKELRLERTRILGGPRDVLHVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTAARIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A317GUG3_9CHLR ----------------------------ADRQI-VLYPDLVFPAASLAKLCIAVELFRRVD -LGQFDLSERFDTADEPRVGGGGMLDYLDPTTLTLHELCFLMIAASDNTAANFLLDLV-GM -GEVNETMRRLNLAGTRLERHFMDFSLR-ARGHDNVTCAKDIAGLLAMAHGNSF---PGAR -NFRELLAGQQV-ADDLRAWLPESAELGHKTGALDAGTFHDAGLLRGPAGS--CVFCLLTD -AQPDLPAARSAVGRVLRVLWESw ->[subseq from] serine hydrolase n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI000D599C62 -----------------------------ADEV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQI-GL -DTVRLLVKELRLERTRILGGPRDVLHVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTAARIAVD-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Caulobacteraceae bacterium TaxID=1978230 RepID=A0A4Q3S151_9CAUL ----LDKGITQLADRIDGRLEVAVQNLDGGEIW-ARNAEQTFPLQSVFKAPLGAAVLSEVD -ARRLSLDEQITIEDMELSPLSPISQAWPGRKYTVRELLVAAVRDSDNTAADVLMRKIGGP -GALKSWLVEKGIIGLRIDRYERELQV---------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. CL-2 TaxID=1499684 RepID=UPI0005097B17 ------KEIKRYLESRIGTYGFFFEDLKSGFVY-GYNENVSMTAAGCMKLPIAVSLIKAVE -DGKVDFLDKVKIKSEDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIL-GM -EKINQDILEMGLKNTKLNRKTTDERD-NHTDVENLTSAYDLNLIWKHLYNGTFLNKDNGQ -MLIDILRRQQI-KNKLALYLCDDYEISSKTGDKY-GVENDTEFIQVPKGD-FSFTVLSSG -LPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase class A n=2 Tax=Streptomyces coelicolor TaxID=1902 RepID=A0A4R8MLL9_STRCH ------------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVA -AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLVEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00036A8FBC -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSLTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADVSARA- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A1C4U1C4_9ACTN ---------------------------GGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Chloroflexi (miscellaneous) TaxID=189774 RepID=A0A1Q7QI46_9CHLR ---ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD -AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG -ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD -RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD -APV--DDADAFISSIGAIVYS-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5GR78_9ACTN -------------------------------EI-GVRADDQVVIASIFKVLLVLEFARQVE -AGQLDPTERVLVTADDRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAAELGLSRTRVLGGPRDLVEVFDPEHTTSSTAREITRLLTLIWRDEAGSPAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DRSRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PM01_9CHLR ---ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD -AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG -ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD -RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD -APV--DDADAFISSIGAIVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536P6Q6_9CHLR ---ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD -AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG -ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD -RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD -APV--DDADAFISSIGAIVYS-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536CZF2_9CHLR ---ELVQQIDGLVRTFPGGSGIWIGDPLSPSPLyTRNADTEVIAASLYKLGILAEAERRVD -AGELHYNDTVVIQDEDITEDGSF--EDAGTELTLDEALEAMITISDNGTALALWHIL-GG -ANIDQTLAKAGMPDFHI---------ALDDSEDHTATPRALGTFLTLLARHQLVSPAASD -RMLARLGRQKI-NNRLPAQLPENVLVAHKTGNLA-GLVHDAGIIYTKSG-PRVVVTMTWD -APV--DDADAFISSIGAIVYS-- ->[subseq from] Serine/threonine-protein kinase PknB n=2 Tax=Desulfosporosinus acididurans TaxID=476652 RepID=A0A0J1FKZ2_9FIRM -------------QDSKGSYFMYLRDNTTKEEYaNSEANDSKVAGGLVYIPIMTTVLIEHF -NGNLNLDKPITVQG--IAGTGKLTRQDSGRSLSVKQLLELMMRYSDNTAANLLIDELGGL -ERINNTMRSLNIDGIVLNRKLMDQQ-AMNRGLENYCSPRGIGSLLSLLAENRIMAAQDCE -YSISIMGNNDH--TGMAKYLPDNILISHQTGILT-GVFNDAGIINTPKGR-VVLVLM--G -EKVDQDTAAEIFGKVARAVVEQ- ->[subseq from] Serine hydrolase n=1 Tax=Arundinibacter roseus TaxID=2070510 RepID=A0A4R4KF94_9BACT --rELTRKIEQAIAGFGGDVGVYVHHIKKNRVV-EIQADTVFPTASMVKIPILCGLFDKLH -SGQLAYDSVLIYRDSLRYDDGIVGSLRDSAKIPLSYVLMLMETISDNTGSLWMQALAGGG -ATINNWLQKQGFVHTRVNSRTPGRADAQRTYGWGQTTPREMAELMTLIRFGGAISPDVSE -RMYRLLGRQFW-DGQALSQLPPEIKVAAKNGAVNR-AKSEVVYVHAPHGD-YVFCITTKN -QKKADNEGYVLLRTLSAILWNHf ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. UCD-OTCP TaxID=1292021 RepID=A0A0M2CWM0_9MICC ------------------------------------------------------------- ----------------------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHEQGFTDTTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N6SAM0_9ACTN -------KLDAHLDTVPGTVSAYVGRLDAEPVW-TRRADVTHYAASTMKLAVLVALHRAAE -AGALDLDAPVPVANASAQPGAPRFWARVGGTASLRWLAQRMIVRSSNLATNLVIGHV-GL -PAVAEVWTLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGLLATGALASPAACA -QMLEVLVAQEH-REDLAAGLPPGTRIAHKSGWVN-GVRHGAGVVFPDDAAPYAVVVCTTR -DAGDDADACALIADVSARVWS-- ->[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=UPI000B870E0B -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPIGVHPDSAVDGSRFEWAAVGSPLPLGDLVRRSLTVSGNLAVNLVLERV-GL -EEVAAVLADAGVTMTTVLRGIEDAPA-REAGLQNLATANDMGKLLTKLASGRLLSPESTA -ELEGILVAQEY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIRPAQGEPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9X6Q4_9ACTN ---------------------------AGGREV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVVVTAADRLGGWGLAGCADDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPATACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -AQPRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI00048AF0EB -------------DRVSGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMITRSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLMADISAR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Pseudonocardia kunmingensis TaxID=630975 RepID=A0A543D0V1_9PSEU --eELAVEITDRAEQVGVRVWLHAVDVDGGAQF-GIDPGGPVVTASVFKVPVALELARQAV -AGECDLAEPVAVDPGHPTPSPYGLATFPHRSLSWDALATLMIGISDNVATDLVLDRV-GK -PAVAALLDRLGLPGTAVPDNCEELLRVLRPAETCRTTPEEMTRLLALIWRDEAAPAEACA -HVRRWMGRQVW-PHRLRSGFADDVRISGKTGTLP-AVRNEVGVVEYADGGRFAVAVFTRA -RDAQAPERDALIGFAAARA---- ->[subseq from] Serine hydrolase n=1 Tax=Tsukamurella conjunctivitidis TaxID=2592068 RepID=A0A5C5S6Z1_9ACTN --------------------------------L-SVGGEQPVVPASVYKVLLLVAAARAVD -AGRLDARTRIVVDPAVSTPPTGIATLSDPVEMSVRDLLRSMIAVSDNAAAGVLMRLV-GL -DAVQRTARDLGLHGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDTAASTEECA -FARSALAGQVF-RHRIASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA -ARNDLPRVDAAIGTVAALAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=Amycolatopsis decaplanina DSM 44594 TaxID=1284240 RepID=M2Z5U2_9PSEU -----IATINERAKEVGVRVRLHAAEVDGTRRI-GVDEHTPVVTASVFKVPIALELARQAA -EGGLDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-RK -EATEKTLRDLGFEHTTVTQDCREVLDALRPEHTCATTAEEITRLLGLIWRDEAAPPAACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVRIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces sp. 111WW2 TaxID=1945515 RepID=A0A2P8ADH0_9ACTN ------------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVT -AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLVEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTAARIAVD-- ->[subseq from] Beta-lactamase class A n=3 Tax=unclassified Streptomyces TaxID=2593676 RepID=A0A1H1QR85_9ACTN ------------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVT -AGQLDPRARVRVTAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLVEELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTAARIAVD-- ->[subseq from] Serine hydrolase n=2 Tax=unclassified Chloroflexi TaxID=167963 RepID=A0A5N9HGV3_9CHLR ----LINRMNTMCLESPFQSGWYLKNLQTKESD-NYYGDVVVPSASTRKIAILMNAMKWIH -EGKLSLDQPIRIDETQYVGNSSGCFQYLRPGVQLYDVLTMMIIVSDNTSTGIVANLL-GL -DSINEFSQSIGMIGTTHRHKLPPLDLDHSLDYTNSTTPNDVGLILELILLGTGSSKELCQ -IALDILLNQKL-NNKLPALLPKGTKVAHKTGTGAR-NYNDAGIIFLEDSPLFILTVFTEN -VPTSLADG--------------- ->[subseq from] serine hydrolase n=1 Tax=Bacillus sp. A134 TaxID=2681970 RepID=UPI0012EE580E --------------------------KSEGNQI-AFNEMKQLRAASIIKLFILAAAYYEKE -RGNIELSKQVNLPDSDMAGGAGVISYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL -DYIQAFIKKIHCNNTKLERKLMDE-KAIQLGLENVTTCYDVMLLLDLFTENHIMPKHRQQ -QILTILENQQF-NSKLTASYDSDIKTFHKTGELT-GAEHDAAIFQTADK--LLKAVVLTE -GWANNGEGQQFHQASGAHIYHY- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_40_15b TaxID=1798594 RepID=A0A1F6I6R6_9BACT --------LEKFLKGEKGSYSIYYKDLATGQEF-GINENKVLTAGSLNKLLIISYLYNLAR -DNKINLEDKITIQKKDIQDYGTGSLRYDGEGYTLKTLTQLGLEQSDNTAAYVLSLRL-GE -DKIQEYGRKLGLASTNMA--------------NNKTTARDMGKILDLIYSGKITSDPLTQ -ELLDFMKDTDF-EDRLVRDLPSNVSAYHKAADATN-MVHDVGIIDPSGRSPFILAVLTSD -IK-DEEEAKKTIGKIAKFIYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces sp. FXJ1.172 TaxID=710705 RepID=A0A176LBP0_9ACTN ----IEDRLEEVFAEAGCKGNVAVLDIDGPGQV-VLGDGELVVAASTFKIAVALELFCQGA -EGRLNLAERVRLSPSQATPGQGFCIFEDEAEVSLRDAARMMMTISDNTATDVLIRRV-SV -PRIHARLAGLGLDRIRLAGTIREEFDSLQPGRVTSATAGQMAALLRLVWRDEAGPGEACA -AVRTILSQQRL-TRKIATGFSAAVRVAAKSGTVPGCVSNDVGVVEFPDGSRFAVAVFTRP -TGPRPPQADPAIGAAARLSVEH- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI0006E29024 -----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HAASRPTVDAAVGRAA------- ->[subseq from] Uncharacterized protein n=8 Tax=root TaxID=1 RepID=A0A0F4VNV5_9CLOT ------KEIKKYLETRIGTYAFFFEDLESGFCY-GYNENVQMTSAGCMKLPIAVSAIKYVE -DGKGSFLDKITINEDDKVYGTGIIHEFNNREYTFFELLVAMLIQSDNTAANKLIDIV-GM -DTINEDIQSQGLRNTKLNRKTAD-ERAVSSGVENITSALDLSKIWKHLHNSSFLNEKNST -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKS-GVENDTALLHLQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium butyricum TaxID=1492 RepID=UPI00040ECFBA -------EIKKYLETRIGTYAFFFEDLESGFCY-GYNENVQMTSAGCMKLPIAVSAIKYVE -DGKGSFLDKITINEDDKVYGTGIIHEFNNREYTFFELLVAMLIQSDNTAANKLIDIV-GM -DTINEDIQSQGLRNTKLNRKTAD-ERAVSSGVENITSALDLSKIWKNLHNSSFLNEKNST -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKS-GVENDTALLHLQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. 13-12-16 TaxID=1570823 RepID=A0A1X4I900_9ACTN -------------------------------EI-AVGADDAVVIASIFKVLLVLEFARQAV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLDRV-GL -DTVRLLAKELGLDRTRVVGGPRDLLEVLDPHHTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMGRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVARYPDGACYAIAVFART -HDASRATVDAAIGRAA------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces hirsutus TaxID=35620 RepID=UPI0006E449EB ------------------------------CEV-GIGADDPVVIASIFKVLLVLEFARQVA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAAELGLERTRIVGGPRDLLEVLDPRRTTASTPREITRLLRLIWTDAAGPPEACS -FVRDLMLRQIF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAVAVFART -HA-LAASRPTVDAAAGRA----- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. CT4 TaxID=2320868 RepID=A0A3R5UAS6_9CLOT ------KEIKKYLETRIGTYGFFFEDLVSGYTY-GFNENVKMTAAGCMKLPIAISIIKEVE -LEKFNFLDKIRIEKEDKVYGTGIIHEFNERDYTIFELLVAMLIQSDNTAANKIIDIV-GM -DRINEIIKEMDLKSTELNRKTNDERH-QHSDVENITSAYDLCVIWKHLYRSTYLSKENST -MLIDILRRQQI-KNKLALYIPDDYDISSKTGDKT-GVENDTELIELNKG-SFAFSVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPLOWO2_01_FULL_39_12b TaxID=1798388 RepID=A0A1F6ARX1_9BACT ---PLKEKIAKALEGTNGIYGVVVRNLKTGETY-SANEHRVFEAGSLYKLWTMTVVINQLE -SGELKEDKVLSQSVSVLNDIEPLAEQTSGTVFSVGNGLKQMITISANLPALLLTEKV-KL -STIATFLTQNGFKESKVGT----------GGEAPTTTPSDMALFFEKLYKGELANQEYTN -KMIDLLKSQQL-NDKLPKYLPQDTVVAHKTGEIGW-FSHDAGIVYSPNGD-YIIVILSES -DSP--PGAEDRIAQVSKAVYEY- ->[subseq from] serine hydrolase n=1 Tax=Salinispora arenicola TaxID=168697 RepID=UPI000368B8F8 -------------DRASGTVSASLGRLGATPTW-TRHPDTTHYAASMMKVAVLVALYRIVE -AGHLDPDSAVPVRNEFDSARPGAAWARVGDTAPLRWLAEHMIARSSNLATNLLLDRV-GL -PAVADAWARGGARHSVTGRGIEDFAAR-AAGITNLVTAADLAALLGNLALGALAAPESCA -AMLDILTGQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSAGIVYPDDAPPYVIAVCTTA -DPTDASPDDDACQLIADISARA- ->[subseq from] KxYKxGKxW signal peptide domain-containing protein n=1 Tax=Streptococcus pneumoniae TaxID=1313 RepID=UPI00136A775D ----IKSEYERLFGNLRGTKSLAIMPTDGTELL-LI-NNNVQRSASTIKLFIMAAAFAKAE -RGELDLSQRYTVKASDIVQASVNLSGAAGKVYTLDNITRMMVETSDNTATNIMINAIGGI -AAVNNEIRRLGYTKTTLNRYMR-IPSQINAGLENYISAIEAADLIKNIYNNSTASDASDR -SMLSKLSNNYY-KLWLPASIQNLAQTWDKPGNDGFGVENDVAIIKRNNRA-YAIALLTQG -TGSNGTTYTNRFAQLGQAIVR-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00036532C1 -----------HLDRIPATVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRDLA -AGRLAHDTAVPVRNEFDSAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLKQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRGLALGALATPESCA -AMLDLLVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCSTS -DRPDDEVACQLLADISARAF--- ->[subseq from] hypothetical protein n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI0013DA0D5B ------------------------------------------------------------- ----------------------------------------AAARQRHNTATNLPLDLLGGP -TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRTVPLAGGLQPAGRE -RRTTSLVANTTGDATIRAGVPAGWLIGDRTGTQAQGERNDVGIVLPPDRAPLVS------ ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2568 TaxID=2512219 RepID=A0A4R1WTT4_9ACTN ----------------RGDIGVWLGGLDGHAVF-THDADRAHYSASTMKLPVALAMMRKVD -AGELALDQPVTVHNDFASAEAPATWAKLGEQVPLSWLATEMITKSSNLATDLVLELT-GV -DAANAVLAEYGSGASVIRRGIDDTGA-QAAKISNLMSPADLAAVLVAVGNDKS---ASGE -YVRDLLAGNTW-NGEIPAGVPEGTRVEHKNGWDLR-IRHDGGIVRPSDAEPFVLVVCTTS -DLAD-QDAQKLIAAIAAEAWDH- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium chromiireducens TaxID=225345 RepID=A0A399IP91_9CLOT -------EIKRYLESRIGTYSFFFEDLESGFSY-GYNENVQMTSAGCMKLPIAVSVIKYIQ -DEKGSFLDRVKIEEEDKVYGTGILHEFDNREYTIFELLVAMLIQSDNTAANKLIEIV-GI -DNINEDIIAQGLKNTKLNRKTSDE-RATGSGIENITSALDLARIWKHLYNSSYLNEKNST -MLIDILQRQQM-KNKLALYIPDDFEISSKTGDKSS-VENDTALIHTQKG-SFTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A2W4N0P6_9FIRM ----LRAEVARFIAGRPQSFGIYFKDLQTGATW-GINERAEIHAASTIKVPLVLYVNRQVA -AGKARMDDRVALRPEDMTGGAGILQRDGFQGYSLRVLTNLAITISDNVATNMLFRHF-GK -DDVGRFMRELGGEVIF------------PG-GRRISTARDMGIYVEAVLDFARRHPLLGA -RILDDMAHSIF-HVGLPGMLPDDVLVAHKEGDIE-GVANDVGIVFSS--RPYILSILSVN -VP-DIDQGFEDIARISKIVYDY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. LHW51205 TaxID=2248752 RepID=UPI000DE80786 ----VAERVGEIFGRAGVRGCLHVVDVDTGGEV-ALRADEQIVIASIFKIMVVLEFARQAA -AGQLDPTERVLAGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRV-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEHTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRA -ERARRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. MOE7 TaxID=1961713 RepID=A0A1W5Y0N6_9ACTN ------------LARADADIQLHAVDLDTGGQV-AVAADQQVVIASVAKILIVLEFARQAA -SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG -DAVGMLVAELGLERTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA -RDARPADLDETIGRVAHAAVQ-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=A0A1D7VY48_9ACTN ---------------------LHAVDLDTGGEV-AVAADQQVVIASVAKILIVLEFARQAA -AGQLDPGAHVTLRAEDRLGGWGIAGCADDVDISLRDCAYFAMSLSDNTAADALIRRV-GG -DAVRMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGTADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GMHMEAGVVRYPDGRRYALAVFATA -RDTRPADLDETIGRVAHAAVE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI0009423E7C -----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HA-LAASRPTVDAAVGRAA---- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora auratinigra TaxID=261654 RepID=UPI000B8575BA ---DVAQRIAEIFGRVGVDGCLHVTDVDAPRREiAVRADEQIVIASVFKILLVLEFARQAV -AGQLDPTERVLVRAADRLGGWGVAGCADDVEISLRDLAYFTMSVSDNTAADLLLRRV-GP -DVPPMLAAELGLARTRIRGGPRELVEVFDPAHTTSSTARELTRLLELIWRDEAGPPAACA -MVRDLMARQLF-WTRLAAGFPPGVRVAGKTGNLP-GLHLEAGVAEYPDGGRYAVLVHART -RRLSRIDVDLAMGEAARVAV--- ->[subseq from] Beta-lactamase n=2 Tax=unclassified Pseudonocardia TaxID=2619320 RepID=A0A1Q8LKT3_9PSEU ------------------------------RDV-DAGAHAPVVMASVYKLFVLVAYCREVD -AGTVDPREPVVVPVPRTPGLTGISALADPVTMSWRDLVTSMVTASDNAAADVVHSRV-GR -DRVAALPAELGLSGTRIRGGTDDVFAALSPVYGSATTAADVTALLALLWRGELASEASTA -FARLLLGAQIW-PHRLRAGFPAPTQVAGKTGTVG-AVRNDVGVVTYPGEHPVAVAVFTHS -ARTTVPRADAAIGAAARVAVH-- ->[subseq from] serine hydrolase n=1 Tax=Megasphaera cerevisiae TaxID=39029 RepID=UPI000A8BCB5F -----------------VHVSLYVRPLDEARPF--IYNERVMPSASLIKVPIMAEAFRQEK -EGRIRFEDMLLVY--DPVEGGSFYGGPPDRKVSLYDLIFHMIVESDNTCANMLMDIL-GA -DRINEGFLRWGMDHTILRRKMMDFAAA-RAGRENMTTVSDMGRFFTLLADGRCVDEERSQ -AMLAILSQQED-NAILPAQIPHSVRVDHKTGELE-GIYHDCGIVYSPRR-VYICCMMADG -IT--------------------- ->[subseq from] serine hydrolase n=1 Tax=Oceanobacillus sp. CFH 90083 TaxID=2592336 RepID=UPI00128E8E44 -------------------------IQSGENQI-AFNEQEQLRSASIIKLFILAAAYYEEE -RGNLDLSKQICIPSSNIAGGAGVIAYLSGKQYTYQQLLELMIIVSDNTATNELIDFI-GL -DNIHAFIQKIHCNNTKLERKLMD-EEAMKLGLENRTTCYDVMLLLNLFTENNILPTYRQD -QILTILENQQF-NSKLTAAYDSTIRTFHKTGELT-GAEHDAAIFQTADK--LLKAVMLTE -GWTNNGEGQQFHQAAGARIYQY- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=A0A193C0J7_AMYOR ----VIETINARAKEVGVRVRLHAAEIDGTRRI-GIDEHTPVVTASVFKVPVALELAKQAA -EGVLDLGEPVTVPPGHPTPPYGLATFRHEVTMSWHDLAILMIGISDNVATDLILDRV-GK -EATGETLRRLGFEHTTVSQDCGETLSALQPAQTCATTAEEITRLLGLIWRDEAASPTACA -DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPT-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAARA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=A0A1G6XBE0_9ACTN -----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HA-LAASRPTVDAAVGRAA---- ->[subseq from] Beta-lactamase (Class A) n=1 Tax=Bifidobacterium callitrichos DSM 23973 TaxID=1437609 RepID=A0A087AB87_9BIFI ------------------------------------------------------------- ------------------------------DNATIDANLQQMITVSSNDAANRLLAVIGGK -GGTTAAIATVTDTAVRYGSGTKELRAASGNAVENWTSARDCGTFLAKVYRGELVSANASK -RMVDLLLGQTR-RTKIPAGVPAGVQVANKTGELA-AVQNDVAIVYG--ARPYVIAVMTND -VDESAATN---ITTLSANVY--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces prasinopilosus TaxID=67344 RepID=UPI00099EB05C -----------------------------GDGV-GVGADDPVVIASIFKVLLVLEFARQAA -AGQLDPRERVRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLARV-GL -DTVRLLAAELGLGRTRIVGGPRDLLEVLDPHRTTASTPREITRLLRLIWTDAAGPPEACA -LVRDLMSRQVF-RHRLVSGFPDDVTVAAKTGTLP-GLHMEAGVVRYPDGGCYAIAVFART -HA-LAASRPTVDAAVGRAA---- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis thailandensis TaxID=589330 RepID=A0A229S1R2_9PSEU ----VIATINARAKEVGVRVRLHAAEIDGARRI-GIDENAPVVTASVFKVPIALELARQGA -EGELDLGEPVTVPAGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK -EATAKTLRRLGFEHTTVPQDCREVLDALQPAHTCATTAEEITRLLRLIWRDEAASPSACA -DVRRWLDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEHPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Micromonospora sp. 4G51 TaxID=2202420 RepID=A0A317DTW2_9ACTN -----------------------------GREV-GVRADEQVVIASVFKILLVLEFARQVA -AGQLDPTERVLVRADDRLGGWGIAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DVVPMLAAELGLSRTRIVGGPRQLVEVFDPAHTTSSTVRELTRLLGLIWRDETGPPAACA -MVRELMGRQLF-WTRLASGFPPGVRIAAKSGTLP-GLHLEAGVAEYPDGGRYAIAVSTRT -ERLDTRDVDLAMGEAARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Paenibacillus spiritus TaxID=2496557 RepID=A0A5J5GAI1_9BACL -----------------------------------LGKDDTYKPASTIKMALVSALMQQVD -NGTLKLSDTVTVEPADVVGGTGSLQKESPKEVTLERLARLMITQSDNTATNVLIDVV-GL -DKVQALMDKLGLKVMHLGRKMFAS--APTPEQDNYINAADLVTLLEKIYDGTFLTTASRN -QIITWMAAQEV-NTKFGTALPD-------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Candidatus Roizmanbacteria bacterium GW2011_GWC2_41_7 TaxID=1618487 RepID=A0A0G0XCY3_9BACT ----LSLAIRNRIAEEEGTYSIRFEDFGTKNAF-GINDEPVVTAASVIKIPALAALYYLAE -QRDIDLNEVITIPESDMQRGTGIIRQDAGATYTIRELAQVMMEHSDNTAVYVLANRVIGL -ERLQELIDSWGLSNTNYL--------------ENNISNKDMNKVMRMMYSGELVKDEENV -EMMGWMDDSDF-EERLPKYIPEEVSVYHKIGNEVR-ITHDVGVIDLPEK-PYYLGVLGIE -IP-DHEHATEVIAQISQMVFEY- ->[subseq from] Beta-lactamase class A-like protein n=3 Tax=Microgenomates group TaxID=1794810 RepID=A0A0G0T751_9BACT ----LSLAIRNRIAEEEGTYSIRFEDFGTKNAF-GINDEPVVTAASVIKIPALAALYYLAE -QRDIDLNEVITIPESDMQRGTGIIRQDAGATYTIRELAQVMMEHSDNTAVYVLANRVIGL -ERLQELIDSWGLSNTNYL--------------ENNISNKDMNKVMRMMYSGELVKDEENV -EMMGWMDDSDF-EERLPKYIPEEVSVYHKIGNEVR-ITHDVGVIDLPEK-PYYLGVLGIE -IP-DHEHATEVIAQISQMVFEY- ->[subseq from] Beta-lactamase n=1 Tax=Chitinophaga sp. MD30 TaxID=2033437 RepID=A0A249SY32_9BACT ---SLQRQIAGFAAESGGEVGVAAKNFATGLEV-RYRDSARYPMQSTFKFPIAMAVLHQVD -EGRLLLEQPIYLDRKWMVPWSPLRDSFPKGNVPLSKLLTLMVSQSDNIACDILIDLIGNE -AMINDYIHKLGVKDLAIVANEAKMHAGWEVQYSNWC------------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Nocardiopsis sp. NRRL B-16309 TaxID=1519494 RepID=A0A0N0AHC3_9ACTN --------------------RVHVRDIDGTGEL-GHRADEPLALASVAKILITLEFARQAA -TGALDPAERVVARRQDRLGGSGTAGFADDVELSLRDCANLAMTISDNTAADLIEERV-GT -EPVHLLVRELGLEHTRFTGGPRALLRH-PPDPATSSTPRDLTRLLQLVWTDAAAPPRACA -FVRELMARQLV-RARLASGFAPPVHVSGKTGTLP-GLRMEAGVVEYPDGHRYAVAVAAVG -AEGNGHEVDAALGRAARAAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus sojae TaxID=582851 RepID=A0A511ZQX6_9BACI --------------------------KSEGNQI-AFNEMKQLRAASIIKLFILAAAYYEEE -RGNIELSKQVNLPDSDMAGGAGVISYLSDKQYTYQQLLELMIIVSDNTATNALIDFI-GL -DYIQAFIKKIHCNNTKLERKLMDE-KAIQLGLENVTTCYDVMLLLDLFTENHIMPKHRQQ -QILTILENQQF-NSKLTASYDSDIKTFHKTGELT-GAEHDAAIFQTADK--LLKAVVLTE -GWANNGEGQQFHQASGAHIYHY- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella sp. ALI-6-A TaxID=1933817 RepID=A0A1V2P0M9_9ACTN ----------------RGAFGVWLGRLDGAAVF-THDADRPHYSASTMKLPVAMAMLRKVD -AGELALDQPVTVHNDFASAEAPATWTKLGEQVTVDWLATEMITRSSNLATDLVLEQV-GV -DAANAILLQYAGDASAIRRGIDDVAAQ-AAGISNLMTPAGLAAVLVAAGNDDG---ASGK -YLRDLLAANEW-NGEIPAGVPAGTRVEHKNGWDVR-IRHDGGIVRPADAEPFVLAVCTTS -ELAD-PDAQKLIAAIAGEAWA-- ->[subseq from] serine hydrolase n=1 Tax=Clostridium sp. C8-1-8 TaxID=2698831 RepID=UPI0013722E28 ------KEIKKYLETRIGTYGFFFEDLVSGYTY-GFNENVKMTAAGCMKLPIAISIIKEVE -LEKFNFLDKIRIEKEDKVYGTGIIHEFNERDYTIFELLVAMLIQSDNTAANKIIDIV-GM -DRINEIIKEMDLKSTELNRKTNDERH-QHSDVENITSAYDLCVIWKHLYRATYLSKENST -MLIDILRRQQI-KNKLALYIPDDYDISSKTGDKT-GVENDTELIELNKG-SFAFSVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Mycobacterium sp. QIA-37 TaxID=1561223 RepID=UPI0007A0E779 ------------------------------PIV-DVDGDRPAVAASVYKIFVLIAAARAFD -SGHLHPEATVRVVPADCTPGPTGISTFSNPVLSWLDLARLMITHSDNTAADVLLAAI-GL -DTVNELTEELGFNSTRIIGGTSALQRAFDPAYTTATSACDTDRALSAIWTGTATSAQSSD -MMKQILTQQIS-QHRIRSAFPRDVTVAGKTGTIGP-IRNEVAVIAFPGEPPMAVSVFTRA -ARADLPNVDRAIGQAARIAI--- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644ZZH6_9ZZZZ -----------LDEERDGKYSFYFEDLDGAYTY-GYNQDVPQTSAGCMKLMLAVAFLKKVE -EGMFSMDELVPIKDEDKKPGSGILYEFIERTYTIRELISSMLVVGDNTATYKLMTLL-GV -DQINIMFREMGLTHTHISN--------LPGNESNTTTASDMAKIIKLLYQKNYLTEKHSD -YIIDLIRRRV--KSKIAFYLPNKVRFASKTGDAP-GIENEVALINTESGN-FVFSIMSHD -LPNS-VYGMISLAKAGM------ ->[subseq from] serine hydrolase n=1 Tax=Nocardia sp. CT2-14 TaxID=2675850 RepID=UPI0012B86802 -------------------------------------------MSSVVKVPLVLEFARQVA -AGQLDPTDRVRATAANRLGGVGTAGCHDDVEFSLRDAAYFALTVSDNTAADLLFDRV-GV -DNVRSLARELGLGATRIMGSLRDILYAVDPLRTTAGTARDMTRMLWLIGEDRAGSPEACR -FVRDLMRQQVY-GHRLPSAFPAGTDIWSKTGTLP-GIRNEIGVVGYPDGSRYAVAVFTVS -HSGRQPAVDRAIGAAARAAIE-- ->[subseq from] serine hydrolase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DF3807 -----EDEIIARAEQVGVRVRMHARAIDGTASF-GIGADEPVVTASVFKVPLAVELADQAE -RGHCDLAEQITVPAGPKVPPYGLATFRHPVTLSLDALATLMIGISDNVATDLVFAKI-GK -PAVRALLDRLGLAGTVLEQDCAELLGALDPAQTCRSTAAEMTALLGMIWRDEAAGPGACA -DVRRWLGLQVW-PHRLRSGFHDEVRISGKTGTLPT-IRNEVGVVEYAEGSRFAVAVFTEA -VDSQAPERDAFIGFAAARAIE-- ->[subseq from] hypothetical protein n=1 Tax=Serinicoccus profundi TaxID=1078471 RepID=UPI000255E558 -----------------------------RHEV-SYAADDLVPMASLYKVLLALAWARLVD -AGDLDPRARHTVSAPDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLDLV-GL -PRLREVAADAGMTATTLHGGTRHHQRVYDPAMSSTTTTRDMTRLLGALWREELVAPESGV -RIRRSMARQVF-RHRLASGFPDDVEIASRTGSLL-ALRHEVGVVTFPGEEPVVVAVLTQA -LNQHLPDVDRAIGEIGRVAV--- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis pretoriensis TaxID=218821 RepID=UPI000A3CD601 ----------------------------------AVGADDPVVLASVFKIPVAVAYAREVV -AGRLDETERTRVGPRYRIGGIGTAGCADDVELSWRDLALFMLTMSDNAATDVIYHRV-GQ -EAVDRVLTDLDLHRTRLIGCCEDLFAVLDPERTTASTPREITTLLEAIWTDRAGDAAACE -RVRTIMAQQIW-PHRISSGFGSDVRIAAKTGTLP-AVRNEAGVLSYPDGRRFAVAVFTRA -DSERQPAVDAAIGKAARLAVDH- ->[subseq from] serine hydrolase n=1 Tax=Serinicoccus profundi TaxID=1078471 RepID=UPI000495057B -----------------------------RHEV-SYAADDLVPMASLYKVLLALAWARLVD -AGDLDPRARHTVSAPDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLDLV-GL -PRLREVAADAGMTATTLHGGTRHHQRVYDPAMSSTTTTRDMTRLLGALWREELVAPESGV -RIRRSMARQVF-RHRLASGFPDDVEIASRTGSLL-ALRHEVGVVTFPGEEPVVVAVLTQA -LNQHLPDVDRAIGEIGRVAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID3343 TaxID=2690260 RepID=UPI0013680E74 -----------------CGGTLCVRSLDSGAEF-ALRADESVIPASVVKVQIALEAETWFA -DGRLDPRERVTLSVADRTPGPGVSLFDDDAEMSWRDLVVLMLTISDNHATDVLLRRV-GV -GAVNATAARLGLLGTVIESDLRTMLDALDPQWGTRTTAYDMVDLLQAIWTDRAGPAAACE -RVRATMAKQVT-RHRIAGGFRTPVRVAAKSGSLVGVIRNEIGVISHPDGSRYAAAVFTRS -RPADDAAINDGIGTATAMAVD-- ->[subseq from] Beta-lactamase regulatory protein BlaB n=2 Tax=Streptomyces sp. YIM 121038 TaxID=2136401 RepID=A0A5B7V3I4_9ACTN --------------------------------V-SLAADTPVPVSSVFKVLLVLEFARQVA -AGQLDPRERVLVTDGQRLGGWGIAGCEDDVEVSLRDLAYFALTVSDNSAADVLLSRV-GL -DTVGMLARELGLARTRIVGGPREALAVLDPGRANASTPREVTRLLDLIWRDAAGPPEACA -RVRALMGRQVF-RHRLTSGFPDDVRIAAKTGTLP-GLHIEAGVVRWPEGDTYAVAVFARS -HAADLTRVDAAIGTAARIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. WMMC415 TaxID=2675222 RepID=UPI0012B455BC -------ALDAHLDRVPGTVSAYVGRLDTPPTW-TRHPDATHYAASTMKVAVLVALHRAAE -AGRLDLDAPAPVRNESALPGAPRFWDRAGGAAPLRWLAERMIVRSSNLATNVIIDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGGLARGRLAAPESCA -AMLDTLAAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHGVGVVAPDDAPPYVIAVCTTT -DAADEDDACRLIARISREAWN-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora taraxaci TaxID=1316803 RepID=A0A561VZ01_9ACTN -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAE -AGELDLDAPVPVVNEDSAQGAPRFWDRLGDTATLRWLADRMIVRSSNLATNVVIGHV-GL -PAVADVWASTGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALAAGAIASPAACT -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT -DPDDADDACLLIADVSARVWA-- ->[subseq from] serine hydrolase n=1 Tax=Rubrobacter sp. SCSIO 52915 TaxID=2653852 RepID=UPI00140727D7 -----------SAGRYAGRYGVVVFDPESGSGV-SLGGGEAFTAASVGKLPTLISLYRAAA -RGELSLDEKISLLPGDYQSGTGVLHNFAPGTMTLRECAYFLVNKSDNTAWAMLDRRL-GV -ENIQAEMREIGARGTDYDMG--------------VTTPEDVFLMLQKISDPAFTDGELSG -EMISAMTDTAF-EDRIPAPLPPDVRVAHKIGSYED-SYGDAGIVFYKDRRRYFIVVLSGG -TGE--GSARAAMQEISRVAYE-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A3D4FKU0_CLOSP ------KEIKRYLDNRDGIYSFYFEDLKSGYTY-GLNENVQMTAAGCIKVPIAVALMKEIE -NNNFNIDDKVSITKNDMVSKYSIIHEFSEKEYTIKELLIAMLIQSDNTAACKIVNLV-GM -DRINELIKDMKLYSTEVRKYPSEN--KIDDNKENVTTSHDLSKCLRLLSNNSYLNQEHSN -LILETLKKNQV-NTGIPFYLPHELQTANKIGTLKC-VENDTALLNLPKGN-FVFTVMSSN ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Terriglobus roseus TaxID=392734 RepID=UPI0009F6C4F0 ---EPEAAIRQVIAQHHGSIALYAHQLNTGKTI-SIDADKPVQTASTIKLALLWTALREIS -LGRATWDEKVTLKPREGVAGSGILHFLDTPVLTLKDVATMMVIVSDNTATNLMIDRF-PT -KLVDDNMAALGYAETWLYKKVFKPADDQPKFGLGKTTPKQIGQLMEKIGRCDTKADAACN -VAIDMLRNQFY-RDTIPRYLERGSGIASKTGSLD-ATRSDVAIIAAKSG-PIVLAVYTYD -NADKDNEGEVAIAKIAQAVVEAw ->[subseq from] serine hydrolase n=2 Tax=Agromyces sp. HY052 TaxID=2585717 RepID=UPI001116D5FD --qALRERIGSIEAELGVTATMHAIDVDTGEEF-GVAADDLVVPASIFKVPVLTELCCRFA -DGSIDPAQGMFIAREAFRTL---SSVFLDDVLSVRDLAVSMMSVSDNRATDILIDLL-GL -DAINERSRRLGLEQTVLVEDCAGLFRVLDASATNRTTPREVTASLALLWDGGVLAPAATA -EARRILSLQVW-PHRLKAGFPSRIRISGKTGTLPY-LRNEAGMIEYPDGGRYAVAVFVRE -TLEENIDADRSIGLIGRAVVDE- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. CV4 TaxID=2478711 RepID=A0A3L7BSM5_9ACTN ----------------------------GGPEV-GVRADEQVVIASIFKILLVLEFARQVV -ADQLDPTERILVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLTRTRVLGGPRDLVEVFDPARTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRMSGKTGTLP-GLHLEAGVAEYPDGGRYAIAIFARA -DQPRRIDVDLAMGQAARTAV--- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Verrucomicrobia bacterium TaxID=2026799 RepID=A0A2V6MLC9_9BACT ---TLEAEIRRIANAAGGEVGVAAWRLDSGPRM-LLNADEAFPMASTFKVAVAGALLGKVD -AGTLSLGTVLPVDKSRYVESEVIADAFIHSGLSIHNLLEVMLSRSDNTATDVLTSAAGGP -GAVTAWVRAQGITGLRVDRDTAGIVRAFDKDPRDSSTPDAMA------------------ ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Kocuria TaxID=57493 RepID=UPI00118427F8 --------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD -RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH -ARVRDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA -FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS -VRRQIAVSNRIVGQIARHCVRSy ->[subseq from] Beta-lactamase class A n=1 Tax=Terriglobus roseus TaxID=392734 RepID=A0A1H4J542_9BACT ---EPEAAIRQVIAQHHGSIALYAHQLNTGKTI-SIDADKPVQTASTIKLALLWTALREIS -LGRATWDEKVTLKPREGVAGSGILHFLDTPVLTLKDVATMMVIVSDNTATNLMIDRF-PT -KLVDDNMAALGYAETWLYKKVFKPADDQPKFGLGKTTPKQIGQLMEKIGRCDTKADAACN -VAIDMLRNQFY-RDTIPRYLERGSGIASKTGSLD-ATRSDVAIIAAKSG-PIVLAVYTYD -NADKDNEGEVAIAKIAQAVVEAw ->[subseq from] Extended-spectrum beta-lactamase VEB-1 (Fragment) n=1 Tax=Acinetobacter baumannii TaxID=470 RepID=V9Y0V6_ACIBA ------------------------------------------------------------- ------------ITPQDLLPWNPIKQEHNGTTLTIEQILNYTESQSDNIGCDILLKLLGGT -DSVQKFLNANHFTDISIKANEEGMHKDRNTQYQNWATPTAMNKLLIDTYNNQLLSKKSYD -FIWKIMRETTTGSNRLKGQLPKNTIVAHKTGTSGAAATNDVGVITLPN------------ ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinospora TaxID=1877 RepID=A0A1C4YIG8_MICEC ---------DARLAGVPGTVSVYAGRLDAAPTW-THAEHTPHYAASTMKVAVLAALYRAAE -AGALDPDTPVPVHNDFPSADGPRFWDRLDRTATLRWLAERMIVRSSNLATNILLGHV-GL -PAVAEVWALAGARHSVTGRGIEDYTAR-AAGITNLVTAADLAALLGALATGAIATPANCA -TMLDVLRAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT -DL-TDPDACRLLADVSVRVW--- ->[subseq from] serine hydrolase n=1 Tax=Embleya hyalina TaxID=516124 RepID=UPI000F819BF1 ----VRGRIGAAFADAGVTGALHAVDIDAGREV-EVGADTLYSTASLHKLCLVTTLFREAA -AGRVELTRRIELPAGPGRSGTGVAAMLDPVTMSLRDLASLTVAVSDNAAADALWDEL-GL -DTVNATMVDLGLTRTVAIEPLRELYAALDPNRSNRGTPRDLTRLLAAIWRDEACGGEYGA -GLRRVLGLQAW-SHRLASGFPDDVRVSGKTGTLPT-MRHEAGVVEYPDGGRYAITVCTRS -ADAALPAADAVIGTVGRLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Actinocatenispora sera TaxID=390989 RepID=UPI0004C366A6 ------------------------------------AATEPVVLASMVKVPLVLEFARQVV -AGQLDPTTRVRLRAADRLGGSGTAGCADDVEMSLRDLARFALSISDNTAADALFAAV-GV -ANVRSLVRELGLADTRIIGGPRQVVAALDPSRTNASTGRDLTRLLAAVWRDEAAPAAACA -MLRGLMATQLT-AHRLASGFPDEVEVVGKTGTLL-AVRAEAGVVSRPDGGRYAVAVGIRL -DRGRQPAADRALGTAA------- ->[subseq from] Beta-lactamase class A n=1 Tax=Asanoa ferruginea TaxID=53367 RepID=A0A3D9ZV96_9ACTN ------SRIAGIFDAVGVDAQLHAVDIDGGAEL-ALRADEPVVLASIFKILLVLEFARQAV -AGQLDPTERVIVRAADRLGGWGTAGCADDAELSLRDLAYFAMAFTDNTAADLLMRRV-GP -DVLPLLAAELGLTGTRVIGGPRELLEVFDPARTTSSTPREVSRLLGMIWRDEAGPPAATA -MVRGLMARQIF-WTRIQSGFPPEVRVSAKTGTLP-GLHMEAGVVEYPDGGRYALSVFALA -RLGAEARRDLAIGEAARTAV--- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Candidatus Levybacteria bacterium GW2011_GWA2_40_16 TaxID=1618458 RepID=A0A0G0RIQ7_9BACT --------IGKFLKTIKGTYSIYYKDLKTGEEF-GIDENKVLTAASLTKVLIIAYLYNQAN -KGKINLEDKIVIQKDDIQDYGTGSIRYEGEGYSLKQLIKLALEQSDNTAAHVLVLKL-GE -DKIQKFGEKLGFSATKMK--------------ENKTSAQEMGRLFELIYLRKITSEPLTR -EFLDFMKDTDF-EDRLARDLPSNVAMYHKAADATN-MVHDAGIIDPGGKNPFILSILTEN -IA-SEEEAKKNIGKLAKFIYDQ- ->[subseq from] Extended-spectrum beta-lactamase PER-1 n=1 Tax=bacterium HR26 TaxID=2035421 RepID=A0A2H5YVL2_9BACT ------------------------RNLTDGTEA-AVQPDRVFYAASLYKLAILYEVYRQER -QGRIDFSQTLTITEKAAEQTLDLLGWSAGSVITVAQAVEAMITVSDNASAVLLGDLV-GW -HNVDQGLRELGLRSTRVNDPELP------------VTAADLAWLLDRMACGQAVDEQASR -EMVELLTRQRV-RDRLPALLPEGVVVANKTGNWTN-ATHDAGIVYSPRA-TYVIVVLSET -AWQS-----EPIARLSAAVYAYf ->[subseq from] serine hydrolase n=1 Tax=Megasphaera cerevisiae TaxID=39029 RepID=UPI0009D2199C -----------------VHVSLYVRPLDEARPF--IYDERAMPSASLIKVPIMAEAFRQEK -EGRIRFEDMLLVY--DPVEGGSFYGGPPDRKVSLYDLIFHMIVESDNTCANMLMDIL-GA -DRINEGFLRWGMDHTILRRKMMDFAAA-RAGRENMTTVSDMGRFFTLLADGRCVDEERSQ -AMLAILSQQED-NAILPAQIPHSVRVDHKTGELE-GIYHDCGIVYSPRR-VYICCMMADG -IT--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. AcE210 TaxID=2292703 RepID=A0A371XNZ3_9ACTN ---ELIETITARAAEVGVQVWLHAADLDSPRHV-GIDADEPVVTASVFKVPVAVELARQAA -DGELDLAERITVPPGHPTAPYGLATFRHDVTMSWYDLAVLMIGISDNVATDLILGKV-GK -AAVAGTLRRLDLPHTAVPHDCGDLLRALTPEETCRTTAAESTRLLGLIWRDEAAPATACA -DVRRWLELQVW-PHRLRSGFADDVTISGKTGTLPS-LRNEIGVVEYPDGGRYAVGVFTRA -VDSRVPERDAFIGFAAARAV--- ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sp. TaxID=1506 RepID=A0A3D5MZA1_CLOSP ------KEIKKYLESRIGTYSFFFEDFESGFSY-GYNENVQMTSAGCMKLPIAVSVIKYVQ -DGNCSFLDRIKIEENDKIYGTGILHEFDNRDYTIFELLVAMLIQSDNTAANKLIDIV-GM -DTINEDICSLGLKNTKLNRKTSD-ERAVSTGIENITSAYDLSRIWKVLHKAEFLDEKNSQ -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKT-GVENDTALLHLQKGD-FTFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=UPI0006AFC8A8 -----AARVRAAFADAGVTGALHAVDLDHDREL-SVGADEPVVLASVFKVPLLVALHHSAH -----DLTRRITLDADRSTGPTGVGGMLDPVTMSLRDLAYLAVTVSDNAAADALADLI-GL -DAVNDTLRELGLTRTLVVHRARDFMRALDPDHTNRGTARDLTTLLRHVWRHDDC-----A -PIRRAMALQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS -ASFTLPAADAVIGTAARLALEH- ->[subseq from] serine hydrolase n=1 Tax=Agromyces sp. Root1464 TaxID=1736467 RepID=UPI0006F5E3E0 ---ALLRDAAEVLRSAGLRASIVVRDLGSGREL-SLAGEDTYPLASVVKLPLALAVLQRID -EGRLDPARPVTLRPDDRTPLVGYCRFQHPTTVAVADLLYMAVCLSDDTAADALFDLC-PP -AAVTASLREAGITGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRSPALAPQ-QD -RLRGLLAMNVM-RQRLAPDLEDDAVWHSKTGTFLH-LRHEIGVLEHADGRAIAIAVLSES -SVQRQPAAEQALGLAAKLL---- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis orientalis TaxID=31958 RepID=UPI00041DA7CE ----VIETINARAKEVGVRVRLHAAEIDGTRRI-GIDEHTPVVTASVFKVPVALELAKQAA -EGVLDLGEPVTVPPGHPTPPYGLATFRHEVTMSWYDLAILMIGISDNVATDLILDRV-GK -AATGENLRRLGFEHTTVSQDCGETLRALRPERTCATTAEEITRLLGLIWRDEAASPTACA -DVRRWLELQVW-PHRLRSGFPDGIRVGGKTGTLPT-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAARA---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. TSRI0369 TaxID=1703936 RepID=A0A1Q5H4Y7_9ACTN ----VAERVGEIFGRAGVRGCLHVVDVDAGGEV-ALRADEQIVIASIFKIMVVLEFARQAA -AGQLDPTERVLAGAADRLGGWGVAGCADDVEVSLRDLAYLAMSVSDNTAADLLLRRV-GA -DVLPMLAAELDLPRTRIVGGPRQLVEVFDPEYTSSSTARELTRLLRLVWRDEAGPAPACA -MVRELMARQLF-WTRLAAGFPPGVRVAGKTGTLP-GLHLEAGVAEYPDGRRYAIAVAVRA -ERARRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Auraticoccus sp. F435 TaxID=2656650 RepID=UPI0012E77B93 ----VADDIRQEWRRAGLSGGFLARHLDSSEQL-GFEVDRAVPLASVAKVPLALVAYDQIV -AGQLDPAQPVELRPEERTLGPTGLSLEHPCTVAVGDLITMALAVSDNAATDALMRFV-PP -AEVTRRMRQWGWHDITLRHHIHELNTQLDTSHANTGTAAALVRLLEAVWTDRVSVPAATA -RLRRTMAHQPS-HRRLGAELIDLTSVVGKTGTFLN-LRHEIGVVTTADGDRVAVAALTVS -SVGEQPEVDAAIGAAARVAVE-- ->[subseq from] helix-turn-helix domain-containing protein n=1 Tax=Streptacidiphilus carbonis TaxID=105422 RepID=UPI0007C6B94B -----GAALQRIFAEADAELHVRALD-GDPGEV-SFGADTPVVLASVFKIAVALEYARQAA -AGTLDRTQRHTVTRAHRSGGAGSDGCQDDVELSLRDAAFLMMSASDNAATDLLLERV-GA -RNVRDTVAGLGFTRFRLGGSCREGAAYLDPAHGRAGTPREITALLAAIWRDEAGPAEACA -EVRELMSRQFQ-SHRLESGFPPQVRVAAKNGTHW-GIRNEAGVVEYPDGHRYAVAVFLRT -RSERLPAADAAIGRSARTAIDH- ->[subseq from] serine hydrolase n=2 Tax=unclassified Bacillus TaxID=185979 RepID=UPI0009E0616E ---RLSKSINKIAQEHQGHLGIAIEW--KGQFF-FLNERDVFPSASLIKLPIMIEGFMQSL -SGTLELDELIRVDNIRKAGGAGIVQYISPQSLSIGDLLTSMIIVSDNMATNYLIERL-GL -ESINSRCQQLGMSNTVLQRKMMDQQA-RERKLDNYTSPLDIIRCLKAIQND------KNQ -SAKRILSNQQL-LDKLPYYLGRSIRIANKTGELDK-VEHDCAIIEYEDE-IIYVAILTDQ -LP-TNQKGKEIIQLIGASIFE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2500 TaxID=2512214 RepID=A0A4R2CQZ0_9ACTN ----------------RGDFGVWLGGLDGHAVF-THDADRAHYSASTMKLPVAMAMMRKVE -AAELALDQPVTVHNDFASAEAPATWAKLGEQVPLGWLATEMITKSSNLATDLVLELT-GV -DAANAVLAEYGSGASVIRRGIDDVGAQ-AAKISNLMSPADLAAVLVAVGNDKS---ASGE -YVRDLLAGNTW-NGEIPAGVPEGTRVEHKNGWDLR-IRHDGGIVRPPDAEPFVLVVCTTS -DLAD-QDAQKLIAAIAAEAWDH- ->[subseq from] Beta-lactamase n=2 Tax=Thermaerobacter marianensis TaxID=73919 RepID=E6SHA2_THEM7 ------EQVRAFIATRPQTFGIYFKDLQTGATW-GINEREPIHAASTIKVPLVLYVNHQVA -AGRARMDDRVVYEPDDLVGGAGILQRFPGKSYSLRILTNLSITISDNVATNMLFRHF-GK -DNVGAFMRSLGGEVIFP-----E--------GRRISTARDMGRYVEAVLDFARRHPLLGG -RMLDDMGHSIF-HVGLPGLLPQKVFVAHKEGDIA-GVADDVGIVFSD--RPYVLAILSKG -VD-DIDRGFEDIARISKIVYD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudonocardia sp. N23 TaxID=1987376 RepID=UPI000BFC461A ----------------------------SEREI-DVGADVPVVMGSVYKVLVLVAFCRAVD -AGDLDPREQVTVEPGPRTPPTGISALTDPVTMSWRDLTRSMITVSDNAAADVVHARV-GR -DRVAALPTELGLPGTRVRGGTADAYALLSPAFGSSTTAADSTRLLTLLWRGELASAAGTA -FARRVLTAQVA-PHRMRTGFPGTAAVAGKTGTIG-AVRNEIGVVTYPGEHPVAVAVFTHA -ARATVPRADAAIGVAARAAVN-- ->[subseq from] Serine hydrolase n=1 Tax=Kocuria sp. HSID17590 TaxID=2419513 RepID=A0A433F856_9MICC --------VTGILRDATGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD -RGELDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH -ARIRDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA -FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS -VRRQIAVSNRIVGQIARHCVRSy ->[subseq from] serine hydrolase n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=UPI000B88CE5A ------------LDGLGGSVSAYLGRLDAPPTW-TRRADATHYAASTMKVAVLAALHRAAE -SGRLDLDAPVEVVNDFASADAPRFWARLGTGATLRWLAERMIVRSSNLATNILLDHV-GL -PAVARVWAAAGARHSVTGRGIEDFAA-RDAGIANLVTVADLAALLAAIATGALASPAHCA -AMRDVLLAQQH-RDDLAAGLPEGTPIAHKSGWVR-GVRHGAGVVYPDDAPPYVLVVCTTT -EGRD-VDACRLLADLSA------ ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis coloradensis TaxID=76021 RepID=A0A1R0KFB3_9PSEU -----IETINDRAEEVGVRVRLHAAEIDGIRRI-GVDEHAPVVTASVFKVPIALELARQAA -DGVLDLGERITIPPGHPTPPYGLATFRHGITMSWYDLAILMIGISDNVATDLILARV-GK -ESTEKTLRRLGFEHTTVPQDCGEVLGALRPAHTCATTAEEITRLLGLLWRDEAASPTACA -DVRRWMELQVW-PHRLRSGFPDGVRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora yangpuensis TaxID=683228 RepID=A0A1C6UYU9_9ACTN ------------LDGLGGSVSAYLGRLDAPPTW-TRRADATHYAASTMKVAVLAALHRAAE -SGRLDLDAPVEVVNDFASADAPRFWARLGTGATLRWLAERMIVRSSNLATNILLDHV-GL -PAVARVWAAAGARHSVTGRGIEDFAA-RDAGIANLVTVADLAALLAAIATGALASPAHCA -AMRDVLLAQQH-RDDLAAGLPEGTPIAHKSGWVR-GVRHGAGVVYPDDAPPYVLVVCTTT -EGRD-VDACRLLADLSA------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora auratinigra TaxID=261654 RepID=A0A1A9A7T0_9ACTN -----AQRIAEIFGRVGVDGCLHVTDVDAPRREiAVRADEQIVIASVFKILLVLEFARQAV -AGQLDPTERVLVRAADRLGGWGVAGCADDVEISLRDLAYFTMSVSDNTAADLLLRRV-GP -DVPPMLAAELGLARTRIRGGPRELVEVFDPAHTTSSTARELTRLLELIWRDEAGPPAACA -MVRDLMARQLF-WTRLAAGFPPGVRVAGKTGNLP-GLHLEAGVAEYPDGGRYAVLVHART -RRLSRIDVDLAMGEAARVAV--- ->[subseq from] Beta-lactamase n=1 Tax=Pseudonocardia sp. N23 TaxID=1987376 RepID=A0A292YVQ5_9PSEU ----------------------------SEREI-DVGADVPVVMGSVYKVLVLVAFCRAVD -AGDLDPREQVTVEPGPRTPPTGISALTDPVTMSWRDLTRSMITVSDNAAADVVHARV-GR -DRVAALPTELGLPGTRVRGGTADAYALLSPAFGSSTTAADSTRLLTLLWRGELASAAGTA -FARRVLTAQVA-PHRMRTGFPGTAAVAGKTGTIG-AVRNEIGVVTYPGEHPVAVAVFTHA -ARATVPRADAAIGVAARAAVN-- ->[subseq from] Serine hydrolase n=1 Tax=Desulfobacteraceae bacterium TaxID=2049433 RepID=A0A3A4X3J6_9DELT --eKLAGELNRMCDRQPFQTGWYLKNLRTGEAC-DRNGDVVVPSASTRKVSILMALLKEVN -EGRFRLDQPVVIEEKYQKNNSGTFQHLTPGFVTLQDAAYMMIIVSDNTCTGTIIDMV-GL -DAVNRLCRSVGMKGTFHRDTIPPFCADHSLEEVTTTTPADQGLLLDLILKGTGCTPELCR -LGIEILSRQKL-SWRLPALLPYGTKVAHKTGTGRAGNNNDVGIIFQGSRPLFILTVYTEH -VPLE------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella soli TaxID=1124743 RepID=A0A4Q7WU65_9ACTN -----NARIRAVFEDAGVRGWLHAVALDEPDLTvEVDADGIVPLASVYKLPLLAGFCRLVD -LGELDPRQQLTLDPSTKTGGPTGLSTFADPVASLRDLALSMMTLSDNASADALLDIV-RL -PRLAELLKSFGLQRTWVRRGTAGNLRVYEAVNASASSARDMTLLLRRLWAGELLSPEQTE -FAKATMHRQVF-MHRLASGFPDGVRVAGKTGTFG-ALRHEVGVVTLPGGTAYAIAVFTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Auraticoccus sp. F435 TaxID=2656650 RepID=A0A6A9V2L6_9ACTN ----VADDIRQEWRRAGLSGGFLARHLDSSEQL-GFEVDRAVPLASVAKVPLALVAYDQIV -AGQLDPAQPVELRPEERTLGPTGLSLEHPCTVAVGDLITMALAVSDNAATDALMRFV-PP -AEVTRRMRQWGWHDITLRHHIHELNTQLDTSHANTGTAAALVRLLEAVWTDRVSVPAATA -RLRRTMAHQPS-HRRLGAELIDLTSVVGKTGTFLN-LRHEIGVVTTADGDRVAVAALTVS -SVGEQPEVDAAIGAAARVAVE-- ->[subseq from] Serine hydrolase n=1 Tax=Embleya hyalina TaxID=516124 RepID=A0A401Z6Z5_9ACTN -----RGRIGAAFADAGVTGALHAVDIDAGREV-EVGADTLYSTASLHKLCLVTTLFREAA -AGRVELTRRIELPAGPGRSGTGVAAMLDPVTMSLRDLASLTVAVSDNAAADALWDEL-GL -DTVNATMVDLGLTRTVAIEPLRELYAALDPNRSNRGTPRDLTRLLAAIWRDEACGGEYGA -GLRRVLGLQAW-SHRLASGFPDDVRVSGKTGTLPT-MRHEAGVVEYPDGGRYAITVCTRS -ADAALPAADAVIGTVGRLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Parcubacteria bacterium TaxID=2053309 RepID=A0A3A4V0U8_9BACT ----VKQKVAEFISKEDLKFSVYYKDLVTGQTF-GIDENKVLTGASLNKLVIVAYLYNLAK -DNKINLEEKVVVQKEDIQDTGSIRYDEPGKVYSLKTLAKLSLEQSDNTAAHLLVLKL-GV -DEVEEYRKRLGLVATDME--------------NNKTSSRDMGKLLDLVYSRKITSEALTL -ELLDFMKDTDF-EDRIPRFIDGDVKIYHKTGDAV-GMIHDVAIVEGK--RKFILSVLTSE -VG-DEEKAKNVIGRLAKIIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium fallax TaxID=1533 RepID=A0A1M4WUJ6_9CLOT ------KEIKKYIETRNGKYSFFFEDLDGGYVY-GYNEHEPMTAAGCMKLPIAVALIKEEE -LGNINFLDKIKIETKDKVYGTGIIHEFGERDYTVFELLVAMLIQSDNTAANKIIEIL-GI -EKINETIKKLGLKNTNLNRKTRD-ERNPEVEIENITTAYDLCMIWKHLYNATYLDRKNST -MLIDILTRQQI-KNKLGLYIPSKYSISSKSGDKH-GVENDTELIHLSKGN-FTFTVMSEG -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Daviesbacteria bacterium RIFCSPLOWO2_02_FULL_36_8 TaxID=1797793 RepID=A0A1F5MGM7_9BACT ----LDKAVATALEGVKGNYGIFIKNFKTGETF-KQNEHMIFHAGSLYKIWIMAETYNQIK -TGDLTEDEQLSRDIEYLNKKFQIAEENAELTLTVANALTQMITISHNYAAMLLTEKI-KL -SSVAKFLKDNSFIESKVGI-----N-----GEDPTTTPADMEKFFEKLYKGEIIDQEYSN -KMLELLKAQKL-NNKLPKNLPTETIIAHKTGELGF-YTHDGGIVYSPKGD-YIIIVMSQS -DSP--PGAEERIVDISEAVYKYf ->[subseq from] serine hydrolase n=1 Tax=Paenarthrobacter nitroguajacolicus TaxID=211146 RepID=UPI000A70B34D ---HITDQIRAIFAEANVTGLLHVRALAPGSEI-SVGADRPVVLASVFKIPVALAFARAVQ -EGRVDPLERVILGSKYRVGGIGAGGCRQDLEMSLGDLAMFMLTLSDNAATDLILERV-GV -DAVNALLSELDLVETHVGGGCLALWELDPRRSLHRSTPRDITHLLSYIWAGRP-DTQANQ -MVRSIMEEQVW-THRLSSGFNDSVIVAGKTGTLPT-VRNEAGVVTLPDGSSYAVAVFLRS -QSDRQPKADAAIGHAAYLAID-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridium saccharobutylicum TaxID=169679 RepID=A0A1S8NAL4_CLOSA ------KEIKQYLESRIGTYSLFFEDLQGNYSY-GYNENVQMTGAGCIKLPIAVSVIKYVE -DGKASFLDKIKIEDSDKVYGTGILHEFNNREYTLFELLIAMLIQSDNTAANKFISIV-GK -DRINQDIVSQGLKNTKLNRKTSDESQ-EDNRTENITSALDLSKIWKHLYNASFLNRENST -MLIDILQRQQM-KNKLALYIPDDYEISSKTGDKSN-VENDTALIRTKKGA-YTFTVLSMG -VPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase class A n=3 Tax=Candidatus Amesbacteria TaxID=1752730 RepID=A0A0G1V2M3_9BACT -------VLNEITATTSGEYGIYVLDPVSGSGY-GVNEEVELPAASIMKVPIMATVYKLVE -SGEMELNDTYTLKESDKRYGSGPLEFVKAGTLTIRRLLSEMGKKSDNTAPVVLTNLV-GT -EKVEDMIGKLGMKQTDFGK--------------NTMTAKDASAMWKTLYNGKILDDEHLK -MMWEDLKDSIY-EERLPAGLPEKLEIVHKVGTDAD-VWADSGIIMPQTTKPLIITILNEG -VK--RAEAEQMVPELTRRIWE-- ->[subseq from] Beta-lactamase class A n=2 Tax=Candidatus Amesbacteria TaxID=1752730 RepID=A0A0G1UVY9_9BACT -------VLNEITATTSGEYGIYVLDPVSGSGY-GVNEEVELPAASIMKVPIMATVYKLVE -SGEMELNDTYTLKESDKRYGSGPLEFVKAGTLTIRRLLSEMGKKSDNTAPVVLTNLV-GT -EKVEDMIGKLGMKQTDFGK--------------NTMTAKDASAMWKTLYNGKILDDEHLK -MMWEDLKDSIY-EERLPAGLPEKLEIVHKVGTDAD-VWADSGIIMPQTTKPLIITILNEG -VK--RAEAEQMVPELTRRIWE-- ->[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=2 Tax=Granulicella TaxID=940557 RepID=G8P1Q7_GRAMM ---ALLAQLQPILAAHHGKVALYAVQLNNGKAV-GIDQNLPVQTASDIKLAILYEAMLEVR -EGKAHWDEKLVLKPGDPVPGSGVLTFFDTPLLTLKDALTMMVIVSDNTATNLMIDRF-GT -DTVNARMASLGLVNTHLYKKIMKPATDQPKFGLGKTTPYEMATLMTRIGRCELHAEA--- ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_39_28 TaxID=1802496 RepID=A0A1F7YA19_9BACT -------EFKNITNKLSGLYGFYVVNLESGFSY-GVFQDEVMQAASLIKLPVFATLYQEAE -SGNINLETKYTLKNSDKLGGSGSLASKPEGTFTYRELARLMGKQSDNTAFNIFRKVL-GD -DKIDKVIEKIEMKNTSLA--------------ENLTSPADIGTYFGKLWNGKIVGSKSKD -EILSYLTDTIY-EDIIPKGVPEEVVVAHKFGRDLH-IINDAGIILTD--KPFVLVVMSQG -IIE--KEAEIALPQIVKTAYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora peucetia TaxID=47871 RepID=A0A1C6UC29_9ACTN ------ERIAEIFERAGVTGCLHVVDLDGGSEV-AVRADEQVVIASIFKVLLVLEFARQVV -AGQLDARERVLVTADDRLGGWGVAGCADDAEVSLRDLAYFTMSVSDNTAADLLLRRV-GA -DVLPMLAAELGLPRTRVVGGPRQLVEMFDPAQTTSSTAREITRLLGLIWRDEAGPPEACV -MVRGWMAQQLF-WTRLASGFPPGVRVSGKTGSLP-GLHLEAGVAEYPDGGRYAIAVFVRA -AQTRRIDVDLAMGQAARTAV--- ->[subseq from] PEGA domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535WM37_9CHLR ----------------GGQWGVYLEDLKSGEGF-GWGQDNLLEAASDIKIPVALYLLHQIE -AGGVQLTDEVTLQAADFMGGTGTLQGNPGDKYKYWDLLNLLIQVSDNTAWRALQRAL-GA -DAIDAYAASIGAPD---------CHQV-----DDNCTAHEAGLMLSQLDRGKLLNPGDTS -FLLTLLENTIY-NERIPYYLG-GITVAHKTGSDGS-VCNDVGIVLLNGH-PFILSMFTWT -DD--YTTGLQAIRDVARAAVDYf ->[subseq from] Serine hydrolase n=1 Tax=Oceanobacillus sp. E9 TaxID=1742575 RepID=A0A1E5K5T6_9BACI ----------------PVSVSVILKN-NTGI-I-CSKETKQMRSASIIKLFILASAYHFKE -IGKLSLTEKIRISTNGHVKGSGVISYLTDIPLTYQQLLELMIIVSDNTASNYLIDRL-GI -SNIQAFIESLGCQQTRLERKFMDVEAQ-KLGKENVTSALDVLRLFDIFTENNFLGENSQQ -HILHILNNQQF-NSKLTAFTEPLVTSYHKTGELK-GVEHDAAIFLQNNK--FLKVVVLTE -GWENNGDGQAFIASFGKVL---- ->[subseq from] serine hydrolase n=1 Tax=Clostridiaceae bacterium TaxID=1898204 RepID=UPI0011C8342B ------KEIKRYLETREGEYSFYFADLKSDYTY-GFNENLKMVAAGCIKLPIAMAVMKEVE -ANNISLEQLVSITNDDKVSGSGIMHELEGRQYSIKELIVTMLIQSDNTAACKLINII-GK -ERVNCIVQDMGLKSTIINKYPSGERE--EFENENITTSYDLCKGLALLSRGKVLNKEHSK -FILEIIRRNQL-TTGLPFYWPKDAKTAHKAGSLE-GIENDIVLLSSEKGD-FVFVVMSRN -LPS-NVYGVS------------- ->[subseq from] hypothetical protein n=1 Tax=Streptomyces rubrogriseus TaxID=194673 RepID=UPI00131F3160 ------------------------------------------------------------- ----------------------------------------AAARQRHNTATNLPLDLLGGP -TAVTAFASGLDDATTRFDRNEPQLNSTGPDDERDTTTPAAIVESMRAVPLAGGLQPAGRE -RRTTSLVANTTGDATIRAGMPAGWLIGDRTGTEAQGERNDVGIVLPPDRAPLV------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00048438AE ------------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGDLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDHSRDEDACQLLADLSA--- ->[subseq from] protein kinase n=1 Tax=Desulfosporosinus sp. FKA TaxID=1969834 RepID=UPI0011251003 -------------QDSKGSYFMYLRDNTTKEEYaNSEANDSKVAGGLVYIPIMTTVLIEHF -NGNLNLDKLITVQG--IAGTGKLTRQDSGRSLSIKQLLELMMRYSDNTAANLLIDELGGL -ERINKTMRSLNIDGIVLNRKLMDQQ-AMNRGLENYCSPRGIGSLLSLLAENRIMAAQDCE -YSISIMGNNDH--TGMAKYLPDNILISHQTGILT-GVFNDAGIINTPKGR-VVLVLM--G -EKVDQDTATEIFGKVARAVVEQ- ->[subseq from] Uncharacterized protein n=2 Tax=Halostagnicola larsenii TaxID=353800 RepID=W0JTB6_9EURY ----LATYLGSYTDRIDEKVGVFLGYPKTASEFyERRACERFASASVIKLVIQYALYADYD -GDLEKLRTVRSPSRENCVGGSGVLNLFDDPTVTLEDLARAMIAISDNTATNELIDVL-GW -GRINDSADTLGMSQTALQRKMMVGLERPDDRPVNVTSPRDCARFFADFVHRETLSCSAYD -RMKVPLRNQNF-TEMFPRYIPSEIELCHKTGFLPT-AALDTGVLFADN--PLVFSVFVDQ -TNRD-SDGADIIAEIGDAVYT-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XQ01_9CHLR ------TSLQPLVASFDGDATVWIARPDQAEPLfSVDPDRPVLAASLYKLAVMLEVERRVE -AGGWSYENPVVIRDEDVTIGS---NEFPGTVLTVDAALEEMITYSDNGSALALLRLV-GA -QRVNATLGAAGLGNFHVA-----LN----ADDDHTVTARAVGTFFALLGRGELLSPAASR -RMLERLQRQHI-NDRMPAKLPAGTVVAHKTGDLV-GYTHDGGIIQSSSG-PLIFVALTQD -APQD--DARQFIAQAAALAYH-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. HSS6-12 TaxID=2720024 RepID=UPI0014396C23 ----------AHLDRVPGTVSAYVARLDAPPTW-TRHADATHYAASTMKVAVLVALHRAAE -AGRVDLDAPVPVRNESALPGAPRFWARAGGSAPLRWLAERMITRSSNLATNLVIAHV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGGLARGTLAAPESCV -AMLDTLTAQEH-REDLAAGLPAGTRIAHKNGWVH-GVRHGAGVVHPDDAPPYVIAVCTTT -DLADEDDACRLIARISREVWN-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium HGW-Chloroflexi-9 TaxID=2013732 RepID=A0A2N2LIQ9_9CHLR ----------AATTNADVTAGVVLLDLASGERC-EVGATREFRTASLYKTVVLAELYRQID -GGLVALTDPLTLEPRHSVDDPPEFALTEAYRTTVGNAAQRMILYSDNASALALREQL-GI -NLVDTAPAWLGMTSTVLGTRF-------------VSTPRDQAELYRRIYAGEVVSANASR -AMFQVLAEQEI-SDLIPAALPSGVRVAHKTGALDT-YLHDAGIVRAPGGD-FVLVVMTEN -TD--FAGAQEVIHEVTAAAFEPf ->[subseq from] Serine hydrolase n=1 Tax=Saccharothrix sp. CB00851 TaxID=1835005 RepID=A0A1Q4WXB3_9PSEU ------ARVRAAFTDAGVTGRLHAVDLDHDREV-SVGADDPVVLASVFKVPLLVALHHSTH -----DLTRRITLDHDRSTGPTGVGGMLDPVTMSLRDLAYLAVTVSDNAAADALMDLV-GT -DAVNRALRDLHLTRTAVVHRARDFMRALNPDHTNRGTARDLTTLLRHIWQHD-----DCA -PIRHAMARQVW-PHRLSSGFPDDVRVAGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -ASFTLPQADAVIGTAARLAVEH- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7D1K4_9PLAN --qSLKQRISELEKRFDGEFSIEVKRLDKPGYF-ELRKDVVRPTASTCKLFVLCELLRRAE -NGEIDLNSEITWKPEFHRGGDGVLRAMVPGQLTIHNMAILMMMISDNIATATLVDLL-GG -ENITRTIRSWGLESSNIHDGLPGGA-NYSKMKQPVSTASDMLSLITKIYRHEVLTPKSCD -EIIRILRAQRC-NDMLPRYIPAKTWIANKTGYGA--CRVEVGIVKAQDVT-FSLAMFFK- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000485E9EB ------------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGDLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDHSRDEDACQLLADLSA--- ->[subseq from] serine hydrolase n=1 Tax=Agromyces sp. MMS17-SY077 TaxID=2662446 RepID=UPI001328E68D ----SEREAAALLREAGLTASVLVRDLRDGREL-GIDADRAFPLASVVKLPLALAVLLDAD -AGILALDERIALDPASRTPPTGYCRFRHPTEAAVEDLLYQAMCVSDDTAADALFARC-PP -ERVTARMRELGIADVTVRHAISELHAQLDVTNANAGTARALVDLLELIW-GDRLSPTVAA -ELRGLLAENLL-RHRLAPDLEDDARWHSKTGTFLH-LRHEVGVLEHADGGRFAIAVLSES -SVYRQPGAEQALGAAARVLHD-- ->[subseq from] Serine hydrolase n=2 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3B9Z2N5_9CHLR ----------------PFKTGWSFHDLVTGETA-NRFGDLVVPAASTRKVAILMTAMQAVN -RGELSLEEPVTIDERWQISDSGVFQFRPGFTITMHDVLLMMIIVSDNACTGIVCDRL-GL -DAINRFSQSVGMTGTVHREGIPQYTLSDARGTVNETTPNDMARLLHVILRASGVTPALAE -LALEMLSRQRL-RARLPFLLPGDTRVAHKTGTSGT-TYNDVGIVYRGDMPRFILAVYTSD -VPAVLPDGRAAPGATSK------ ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00036C34AE ------------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDHSRDEDACQLLADLSA--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0005268FF0 ------------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA -SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG -DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA -RDARPADLDETIGRVAHAAVQ-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. 15K316 TaxID=2530376 RepID=A0A4R4QLI9_9ACTN -------DLDAQLDTAPGTVSVYVGRPGAEPAW-TRRADATHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVVNADSAQGAPRFWARVGGTAPLRWLAHRMIVRSSNLATNLVIGHV-GL -PAVAEVWSLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGALATGAIASPAACA -EMLDVLVAQEH-REDLAAGLPPGTRIAHKNGWVR-GIRHGAGVVFPDDAAPYAVVVCTTR -DAEDDADACALIADVSARVWA-- ->[subseq from] hypothetical protein n=1 Tax=Gulosibacter sp. Marseille-P7157 TaxID=2479839 RepID=UPI000F63F050 --------------DYGCRWSVLVRDIDTGEELlSHRPDRVLSTASIGKVFLLHRLLREVD -EGTRSLDEVVARRPSELIGGSGIWQLLQQPTFSLYDLGAFIGAVSDNSATNTLARVV-GL -DAVTEHTRALGYEHSRLNDIIRWPIPPGMAPRLSEGNASELVDFVERVQRGDGLSPASSD -VLRGWFGAGMD-LSMVGSVFDNGVWFWNKTGTLTT-VRADIGMVMTPTQR-VAYAALAQW -DR-DEDARGPVLETMAE------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_13_37_7 TaxID=1798369 RepID=A0A1F5YJS9_9BACT -----VDKLEGIISGKTGTYSIYYYDIKSGIST-GINEKMVITAASVNKIPILAALYYLAG -NNTLDLEKIIVPQPSDIQNGTGIRYDPTGTPYSIKTLARLMIEKSDNTAAYLLGTHIVGL -KKIQNLINDWGLTQTDMY--------------KNSSSVYDQSIILIKMYQKEITTPSLTA -EMLGFMDKTDF-DDRLPKGVPEGITIYHKTGDEV-GKVHDVGIIDLPQR-PYYLGVFTTD -IT-DIEDAKKNIALISSAVYD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces lydicus TaxID=47763 RepID=UPI0009821538 ------------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA -SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG -DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA -RDARPADLDETIGRVAHAAVQ-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=UPI000C182F6F ------------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA -SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG -DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA -RDARPADLDETIGRVAHAAVQ-- ->[subseq from] Serine hydrolase n=1 Tax=Mycobacteroides chelonae TaxID=1774 RepID=A0A1S1KXE9_MYCCH ------------------------------PIV-DVDGDRPAVAASVYKIFVLIAAARAFD -SRRLDPEATVRVVPADCTPGPTGISTFSNPVLSWLDLARLMITHSDNTAADVLLAAI-GL -DTVNELTEELGFNSTRIIGGTSALQRAFDPAYTTATSACDTDRALSAIWTGTATSAQSSD -MMKQILTQQIW-QHRIRSAFPRDVTVAGKTGTIGP-IRNEVAVIAFPGEPPMAVSVFTRA -ARADLPNVDRAIGQAARIAI--- ->[subseq from] serine hydrolase n=1 Tax=Brevibacterium sp. 2SA TaxID=2502198 RepID=UPI0010F59328 ------DEINGVWTSLGAQGFLYAEHLGTHRSL-GIRESARIPLASVGKVAVIAGLLDAAA -DGTVDLTQRLLVDPAHSTPGTGIAGLLDPVEMSVRDLAAMALSVSDNAAADTLFDLV-GP -DRIMAVLHRAGIRSFEVTSPMSHLYDLLPDSAFNTGTVRATAKLFELIHTGQLLGPEGSE -TLRRLLRKQIF-RHRIAAGFPDAVQYYGKTGTFLN-FRHEAGVVVDSDGSAYSIAVFTRS -SIATQPELDASIGYCARLAIEH- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XEZ1_9ACTN -------------------------------EI-GVRADDQVVIASIFKVLLVLEFARQVE -AGQLDPTERVLVTADDRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAAELGLSRTRVLGGPRDLVEVFDPEHTTSSTAREITRLLTLIWRDEAGPPAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DRSRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037C91F3 -------------DRMPGTVSAYLARLDAVPTW-TRRPDTTHYAASTMKVAVLVALYRALA -AGRLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLHWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDRSADEDACQLLADLSA--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Roizmanbacteria bacterium RIFCSPLOWO2_01_FULL_38_12 TaxID=1802061 RepID=A0A1F7IYX4_9BACT ----LEKNITEILNNKQGDYGIYFKDLKSEKTF-VLNADREFQTASLYKLWVMAETYRQIK -QGKLDKEHVMTAKIAELNEQFKIASKDMDDEYTVFDALNEMITISGNYSAFILGRQI-RL -FNVSDLLESYKLNHSSIGDNAIGIP---------TTTARDTGVFFELLYKGELIDEKSSI -AMLELLKKQQL-NDKIPRHLPEDIEIAHKTGELAP-FNHDAGIVYTDNGN-YIIAILSET -DD--QTHAEEVIANISKTVYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardiopsis sp. Huas11 TaxID=2183912 RepID=A0A495L6V3_9ACTN --------------------RVHVREIGGPGEL-GHRADEPLALASVAKVLITLEFARQAA -TGALDPAERVVARREDRLGGAGMAGFADDVELSLRDCANLAMTISDNTAADLLEERV-GT -EPVHLLVRELGLEHTRFTGGPRALLRH-PPDPATSSTPRDLTRLLQLVWTDAAAPPRACA -FVRELMARQLV-RARLASGFAAEVLVSGKTGTLP-GLRLEAGVVEYPDGRRYAVAVAAVG -VQGDGHDVDAALGRAARAAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 76 TaxID=2035220 RepID=A0A2G6XX47_9ACTN ------------LARADADIQLHAVDLDTGGDV-AVAADQQVVIASVAKILIVLEFARQAA -SGQLDPGAHLTIRSEDRLGGWGIAGCADDVEISLRDCAYFAMSLSDNTAADAIVRRV-GG -DAVGMLVAELGLDRTRFLGGPRHLLRVFDPRRTTSSTARDMTRLLGLIWHDRAGPADACA -AVRRLMTRQLS-STRLASGFPPPVTVAAKSGTLP-GVHMEAGVVRYPDGHRYALAVFATA -RDARPADLDETIGRVAHAAVQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium cadaveris TaxID=1529 RepID=A0A1I2JNR1_9CLOT ------KEIKKYLESRDGEYSFFFEDLDCGYIY-GFNEDKLMPSAGCIKLPIAMALLKQCE -GCKLNLMDKVKIGPKDKVNGNGILHEFSDREYTIKELLIAMLIQSDNTATNKIISIL-SI -ENINETIKAMGLKNTKLNIVAMEEK-LHDGINENMTTALDLSICWKHLYKESFLNAENSE -LLLDILKRQQL-KNKLSYYFYSKTKVASKSGDLKN-IENDSILFEIPQGN-FTFTVLSDE -L---------------------- ->[subseq from] Beta-lactamase n=1 Tax=uncultured Clostridium sp. TaxID=59620 RepID=A0A1C6LE36_9CLOT ------KEIKRYLESRIGTYGFFFEDLKSGFVY-GYNENVSMTAAGCMKLPIAVSLIKAVE -DGKVDFLDKVKIKSEDKVYGTGIIHEFNEREYTVFELLVIMLIQSDNTAANKIIDIL-GM -EKINQDILEMGLKNTKLNRKTTDERDN-HTNVENLTSAYDLNLIWKHLYNGTFLNKDNGQ -MLIDILRRQQI-KNKLALYLCDDYEISSKTGDKY-GVENDTEFIQVPKGD-FSFTVLSSG -LPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A521UR37_9CHLR ----LDNRIRQQLGTRITSYGVVVKRLADGRGT-VINPDQEFYAASVYKLFVMFEVFKQRE -LGLLSFDEVLTVTPPYQEFQIGDLRWPLWTEVSIRNLLEAMVTESDNVAAMMLYDKT-GG -RNMAQELTSIGLTHTDVNTD------------RLPTSAGDVAILLEMIARKQAINAAASQ -EMIDLLSRQKI-DGGLLTLLPKETKVAHKTGSWDN-ASHDVGVVYAPSGA-YVIAMLSDR -AGE-----LKPIAELSRLVYDYf ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. NRRL B-16802 TaxID=1415541 RepID=A0A0M8XIL9_9ACTN -------DLDAHLARVPGTVSAYVGRLDGPATW-TRHADASHYAASTMKVGVLAALYRAAE -AGSLELDAEVPVVNEDSAQGAPRFWDRLGGDASLRWLAERMIVRSSNLATNLVIAHV-GL -DAVAEVWSLAGARHSVTGRGIEDFAAR-GAGITNAVTAADLAALLGALATGRLASPASCA -AMLDVLLAQEH-REDLAAGLPEGTRIAHKSGWVR-GVRHGAGVVLPDDAPPYVIAVCTTT -DLADEDDACLLIAHISAQVW--- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium RIFOXYD1_FULL_39_9 TaxID=1802649 RepID=A0A1F4X608_9BACT -------KLKNSFAEQGNKFGFYIEDISTGKTY-AYNENVKIYAASMYKFPVAVTVLNEIQ -KKNMALTTELTYTQADFEGGTGSINRNSFGTFSIEQLLTNLIDYSDNVAQNILLHRI-SK -PQVGALINQ------NLDSTSGSLFAA-----ENVTSPAEMGNFLKNIYKGEQLTQENKN -LLFNEMAQTVF-DDRITMHLKEGLTFSHKIGSWDTGSWHDCGIVFGKQD-KFVVCVMSQN -TN--------------------- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004229E42 ------------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWAQAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPTGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDHSRDEDACQLLADLSA--- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E7L426_9PLAN ---ELPQQIEQLEQKYVGTFSIKAHRLDADGHF-SLRPQTVLPTASTCKLFVLCELFRQAE -EGTIDLRAPISWKPEFYRGGDGVLRAMIPGQLSIHNMAVLMMIVSDNIATATLVDLV-GP -DNVNRTMKSWGFAATNIFDGLPGGPNA-AEMKQPVSTAHDLCTLMQRIYRHDVLTPESCD -EIIRIMRAQRC-NDMLPRYVPAKSWIANKTGYGA--CRVEVGVVKTAEV-TFSLAMFFRP -HQPPA------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5WCD3_9PSEU ----LAESIAEQWARAGVRGHLLARNLDTGEQF-GFDVDVAIPLASVVKVPLALAVLERVA -SGALDPARQITVDPATSSLSTGVSAFRYPATLAVGDLVHMMLTVSDNASSDVLLDLI-GI -DGLTGSLRAWGCADIHVRHRLHRMYETLDPAHANSASAAALVDLLHRVWLDRISEPAATA -ELRRLMSLQVF-THRLASDLRDTVRVSGKTGTFLH-LRHEIGVVEADSGDRVAIAALTRS -TRRAAQDIDLAIGSAARSAF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2569 TaxID=2512220 RepID=A0A4Q7PXV5_9ACTN -----NARIRGIFEDAGVRGWLHAVSLDEPEASvELDADAVVPLASVYKLPLLAGFCRLVD -LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL -RRLAQILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRRLWAGELLSAEQTE -FVKTTMHRQIF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] serine hydrolase n=1 Tax=unclassified Streptomyces TaxID=2593676 RepID=UPI000379F64D ----------------------------GAAEV-AVDADEPVVIASVVKILLVLEFARQVA -AGQLDPRERVRITAADRLGGWGTAGCADDVELSLRDLAHFTMSVSDNTAADLLLARV-GL -DTVRLLTEELGLTGIRLVGGPRDVLEVLDPARTNAGPPREITRLLRLVWSDGAGPPQACA -WVRELMGRQVF-RHRMVSGFPDEVTVAAKTGTLP-GLHAEAGVVAHPDGGRYAVAVFART -REATRAAVDSAIGTATRISV--- ->[subseq from] serine hydrolase n=1 Tax=Deinococcus proteolyticus TaxID=55148 RepID=UPI0011D26DF2 --------------------GLLIQDE-AGRDLcSLNAEAVFPAASLIKLPLLVLGLQAAQ -RGDVALVECLPLPAAEHVPGAGVLHELDAGLLTWRDLLTLMIVVSDNTATNMVIERL-GL -ERVQVALPGLGLTHTRLVGKLQQQNAAQRRGERNQTTPRDMLRLLQNLRQGEYLDASYTA -LALDILGRQQL-RDLMGRRVPCGYPVLSKSGELP-GVHHDAGWLLTP--RPLAVACLSLG -GEDP------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_36_15 TaxID=1798586 RepID=A0A1F6HNS1_9BACT --kALESIIQNILKNDKNYYGIVIDNLKTGERY-YFNEDKIFNSASLYKLWVMAVVYQKIE -NGRISKTNILSENVVDLNEISTESAELTQGTWPVQNALQLMITISDNYSALLLAEKI-GL -VSISDFLKKYGLSESKAGNLYKD----------PVTSAQDAANFIRQLYDGQLASSENTL -EMIDLLKNQQI-NTKLSKNLPKNTVIAHKTGELN-GFSHDAGIVYSQKGD-YIIVILSKT -DHP--LETNENIAEISREVYDYf ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces malaysiense TaxID=1428626 RepID=A0A1J4Q6Y6_9ACTN --------ARAIFERAGCTGSLLVRPLDGSAEF-SVDADQLVVPASVVKVLVALAAETWFA -EGRLDPRERVVLGAAERTPPVGVSLFEDDAELSLRDMVVLMLTISDNPCTDMLVHRL-GL -DALNATAARLGLRNTVVRSDLRTMLDALTPGAGTSTTARDMVRLLRLVWSGQAGPEAACA -RVRAVMARQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSCPDGRQYAAAVFTRS -RPADEAAVNAAIGAAARAV---- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037CE890 ------------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDDEDARQLLADLSARA---- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI00140BD29C ------------------------------------------------------------- -----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHEQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Serine hydrolase n=1 Tax=Bifidobacterium callitrichos TaxID=762209 RepID=A0A5M9ZFQ0_9BIFI ------------------------------------------------------------- ------------------------------DNATIDANLQQMITVSSNDAANRLLAVIGGK -GGTTAAIATVTDTAGRYGSSTKELRAASGNAVENWTSARDCGTFLSKAYRGELVSANASK -RMVDLLLGQTR-RTKIPAGVPAGVQVANKTGELA-AVQNDVAIVYG--ARPYVIAVMAND -VDES---AAANIATLSANVYQAf ->[subseq from] hypothetical protein n=1 Tax=Lactobacillus sp. CRM56-3 TaxID=2678357 RepID=UPI0012D3B59E ----------------KWTVAVTSLDGDQHAYMtNWSPGHAQSSASTIKLFILIRYYQELK -QGTIHASDRYTLRKADKVEGSGILHKKVGTQYTMSQLVKLMIEKSDNIATNVLINKLGSF -KGVDQTISQVGPHYSSLERKMMDISD-PDNGRSNRINAWEAVQTLRAIYRGHLIDASADQ -AMMTPMLKTEN-RTKLPANLPSGAICWNKSGESNRGVENDMGIIKYQGH-VFMIAALIEM -DGATEEQTESQVAAIAR------ ->[subseq from] Serine hydrolase n=1 Tax=Acidiferrobacteraceae bacterium TaxID=2024893 RepID=A0A2E9RCV6_9GAMM ---ALENELNQLCDEQPFHTGWSVKNLRTGTVL-ERHGSVVVPSASTRKIAIMMAALKAVN -EGELSLSQPVTMASRFKNNDSGCFQHLQSDFIQLQDALVMMIIVSDNTCTGAVADLV-GL -EAINALCQSIGMADTVHRYGIPGMAGYLPAEKTNSTTPADVAXLLELILKGVGCTSELCQ -LAIDILSWQRL-RNRIPARXPLGTKVAHKTGTTAK-NYNDAGIVYADGVPLFLISAYTDS -VPVE------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A315X4X3_9CHLR ---ALADAILGALARHPERASVAVVNLDDGRWA-AYDADRVQYAASTFKLAVLYEVERRVS -AGELTYDDRVLLDEEAVGEDLGTLERVPEDGVSVGEALDAMVTLSDNATAVALLRHV-GP -SAVDETLRAIGLTTMSVNTKELP------------ATAADLALLMRAIVTGEGVGDAQRE -HMRDLLLGQTI-RSGIPAALVTGLAVGNKTGTWPD-ITNDVAFVESDAGT-YVIAVTAEG -DW-----NWALVSDVSRAVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora ureilytica TaxID=709868 RepID=A0A3N9XRH5_9ACTN ------------------------------REV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVVVTAADRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPATACA -MVRTWMAQQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_01_FULL_37_17 TaxID=1798588 RepID=A0A1F6GWE9_9BACT --qQLTAIVAESVKGKNGTYAVAVLNLKTGEEY-YLNKHRVFDSASLYKLWIMGYAYKKIE -NGLLDKNLLISDSIENLNRASESAEKNIGGILTVKNALDQMISRSDNYSALLLSSKL-GL -SNVKIYLNEYGLSNSNIGTK----------DSNPTTTVYDTFQFLYKLYYGELANQEYTD -EMLSILKKQVI-NQKLPKYLPDSLDISHKTGELGK-FSHDAGIVYANNG-PYIIVVLSET -NSK--NNADETIANISQEVYNYf ->[subseq from] serine hydrolase n=1 Tax=Actinoplanes sp. LAM7112 TaxID=2486853 RepID=UPI000FDABD6E ---------------------LHAVDIDTGRSV-GVGSDDQVVIASLFKILVVLEFARQVV -AGQLDPRDREVVRAPDRLGGWGTAGCADDVEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DVVPMLAAELGLSRTRVVDGPRQVLEVFDPAQTTSSTPREITRLLSLIWRDEAGPAAACA -MVRELMARQIF-WTRLPSGFPADVRVTTKTGTLP-GLHIDAGMVEYPDGGRYAVAVFART -RRARRIDVDLAIGEAARSAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Anaerobacillus macyae TaxID=157733 RepID=A0A0J6CZH7_9BACI ----VSERILDCFRTLEGNQSLYVFAP--DGEI-ALNEDQPVSSASIIKLAIMITALKKVD -NRELSLDSIIPIELSNKVEGAGVISFLSNDLWTLSDLIKLMIVSSDNTATNQLIELL-GE -AEINHTMKCAGAYHSKLMRKMMDRE-AFKDGRDNMISGKDTYLLLNELVTTHLLSESLME -WGTTVLMQQQL-KDKFPAKIAQNNVLAHKTGELP-GVEHDSGILFTSKG-PVIYAFLTAG -LI-ENRYGRDAISNAGRLLYDYy ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Shapirobacteria bacterium CG11_big_fil_rev_8_21_14_0_20_40_12 TaxID=1974889 RepID=A0A2H0KFF1_9BACT -----KKSIESILLPLRGKYGIFYEDIGSKNSF-GINEKEVFTAASLIKMPVLITLYREAE -IGNINLDEVYKLQASDKREGAGALQNKPGFEISYRKIAELMGKQSDNMAFNVVANKL-GT -EKIQNTINALGMKNTSYA--------------ENLTSPVEMGLLFRKLYLEKIISDKNRD -EILSFITDTIW-EDRIPVGVPEGINVSHKIGTEV-GVISDAGIVFGP--KPFILVIMSQE -VNE--IEARKALPEITKKIYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Lentisphaerae bacterium RIFOXYA12_FULL_48_11 TaxID=1798578 RepID=A0A1G0ZTU9_9BACT ----------TVTSNVHGHFSVYIEDLKTGMWW-GLDEKESYNAWSLLKVSTLVALLKKAE -REQISLDEGIVLTPEELKYESPYIEKVTGSFMSIKELAERMIEGSDDAAAMALCKKL-SF -DEFQECFRAMAMPLATPPNILPR------------VSPEQYANLLRSLYRADYLDKTSCD -VALSLMSSTVF-SDQLRAGIPGEIQFAHKVGFNGTGDSHDCGIVFLSNR-PYVICVMSTG -TTK--EEADRVMSSLSRAVYE-- ->[subseq from] Serine hydrolase n=2 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6WDM7_9BACT ---ELVERLDALCDAVPFHASWYLKDVATGARA-DRHGDVPVPSASTRKVSIMMAALAAVH -AGKLALDQRLTVEARYQNNDSGTFQHLTPGFVTLRDAIVMMIIVSDNTCTGMVTDLV-GL -PNVQRWCETVGMTATIHRYGIPKMAPDHPLDQVTTTTPNDQGLLLELILKGTGSTPDLCR -LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGAR-GYMDAGILFKDDRPLCILTAYTDR -VPAALPDGTPGFAAAAQLI---- ->[subseq from] hypothetical protein n=1 Tax=Caulobacter sp. CCH9-E1 TaxID=1768768 RepID=UPI00082AFFC4 ------------ARAAPALLGVAAEDLGTRQIW-AFNGDQAFALGAAARVPILAAVMAERE -AGRLDPNETIQVRDVDLSPPSAIADAWPGRAYAVTEL-EALARAGDNTALDLLAKRIGGP -GAVNGWLGVKQLGGISVDLYRRQAETRRVADPRDTTTPVGMVRLLEAFNTREVFASADPR -PLLG----ND--PGYLAAALPKDAKIWQAAGSARRDESHAVALIELKDGRRVALAVFLSG -STADAATREALVAEAGRTVLKSf ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2DNU6_9BACT ---KVETQFAELAKKLPGVYGLYIKDVGSGREF-KYNDATEFYAASLYKVPIGAAVLKEVE -AGKLKLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY -KNVQETFNEI-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGNYLNDANKK -YLSDLMTNTSF-EDRVSAYLKDGLTFSHKIGSWPD-SWHDCGVVYTDNESELIVCLMSQR -AP--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Microgenomates bacterium TaxID=2093373 RepID=A0A3A0BFX4_9BACT --------------KRGVVVAIQMEYLNTGSYL-SINQNYRMLPASLTKVPVAMMVMRRIE -QGTLSFDQILELKDEDRDSWGEMYKLPVGTKMSLREVIEKSLTLSDNTAHKMLYRLV-GV -QEAQDMSQELNLEDL---------F-----DKEGKISAREYARLLRSLYSSSYLKAEYSQ -QLLDLMTRDQV-VKFLIRGLGPDVKYAHKFGESSY-SYLDAGIVYVPNR-PYVLVVMVHD -EASRELAGEQIFEKVAKLTYEY- ->[subseq from] CfxA2-like beta-lactamase (Fragment) n=1 Tax=human gut metagenome TaxID=408170 RepID=K1U1B8_9ZZZZ ----------KVIKDKKAEIGIAVI-LDAQDTV-TVNNDDRYPLMSVFKFHQALAVADYLN -RNGLTPDTEIFIPEEELVPYSPLRDEFPEGELSVSRLLEYSLQLSDNNACDILFEHTGGP -AATDRYVRSLGLCNFAIAATEQQMHDDPQTCYENWSTPLEAAALLELLVTEQ-------- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536D0A7_9CHLR ---DLASALDQAAAGVPGMVSVVVVDLDSGYVY-ERRADERVEAASLFKLFVMAALYRRAL -DDPQLFEATVPVSRPRLTAGQV---DYVLEPVAVREALEEMIDWSDNEATAALVELL-GT -DEVNATIASLGLRDSVVRSGEASGN---------STSARDIGRFLTLLARREIVSPEASD -AMTWLLLRQGI-NDRLSLGMPKDALFAHKTGNSA-GTFHDAGIAWTAWGE-RVLVVLTDG -VA--APDARALMKDLGYW----- ->[subseq from] serine hydrolase n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=UPI0013625D91 ------------------------------------------------------------- ---------------------------------SIESLINSMITVSSNDAFNTLFYKYLGK -GTVNKFCKANGYKKTQQYRPCGVGDES--GPKGNKTSAADCGMLLEKIYRGKMVSRAASQ -KMLNYLKRQTI-RTKIPRGVPYGIQVANKTGEDGT-IQNDVAIVYGKKT-TYIICVFSNT -NNPG--RAYNCIAEISRMVYN-- ->[subseq from] Beta-lactamase n=2 Tax=Granulicella sibirica TaxID=2479048 RepID=A0A4Q0SZR8_9BACT --qELRGTLTAVAETHHGKVALFASQLNTGKTV-AIDADVPVQTASVIKLTILFEAMEEIR -AGKAKWDEKITMPAGYAVGGSGILTFFDAPMLTLKDVLTMMIIVSDNTATDLAIDRF-GV -DAVNARITWIGLKDTHLYKRIGKMPEDQPKFGLGKTTAREMARVMERIGRCQLAGPGEAA -LVAMNMLRNQFYRETIPRYLEKGSGIASKTGSLD-AVRADVAIVAGKTG-PIVISIFTYG -NTDHDNEGEVTIAKLAKLIVTAw ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora eburnea TaxID=227316 RepID=A0A1C6V512_9ACTN --------LDARLDRVPGTISVYVGRLGARPTW-TRRADATHYAASTMKAAVLVALYRAAE -AGRLDLDDPVPVRNGSALAGAPRFWARVGGNAPLRWLAERMIIRSSNLATNIVIDHV-GL -PAVAEAWTLAGARHSVTGRGIEDSAA-RESGIDNLVTAADLAALLGELALGALASPAGCA -SMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWIR-GIRHGAGVVFPADAPPYTIVVCTTT -DLADTDDACRLIADISAQVWA-- ->[subseq from] Serine hydrolase n=1 Tax=Plantactinospora sp. BB1 TaxID=2071627 RepID=A0A2R4FGA7_9ACTN -------AITGIFDEVGVDARLHVTDIDGGAEL-GVGADDQVVLASIFKILLVLEFARQAA -AGQLDPTERVVVRAEDRLGGWGTAGCADDVEVSLRDLAYFAMTVTDNSAADLLLRRV-GP -DVLPLLAAELGLTRTRILGGPRQLLEVHDPERTTSSTARDVTRLLGLIWRDEAGPAPAGA -LVRELMGRQLF-WTRIASGFPPGVRVAAKTGTLP-GLHAEAGVAEYPDGGRYAIAVFART -RRTRRIDVDLAIGEAARTAVE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. A202 TaxID=2572899 RepID=A0A542EZ80_9ACTN -------------------------------EI-GLRADDQVVIASIFKVLLVLEFARQVE -AGQLDPTERVLVTADDRLGGWGLAGCTDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAAELGLSRTRVLGGPRDLVEVFDPEHTTSSTAREITRLLTLIWRDEAGPPAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFARA -DRSRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Tsukamurella pulmonis TaxID=47312 RepID=A0A1H1B7V5_9ACTN --------IDGVFADAGCNGWLHARVIGHPAAL-SVGGEQPVVPASVYKVVLLVAAARAID -AGRLDPRARVSVDPACATPPTGIAALTDPVEMSVRDLLRSMIAVSDNAAAGELMRLV-GL -DAVQESARTLGLSGTRIVGGDAEIHAAYDPSFGSATTAADMTALLAAIWTDTAASPAQCA -FARSALGGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVSVVTYPGEHPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Aureimonas sp. AU40 TaxID=1637747 RepID=UPI000783E1C2 ------------GDETCGRLSLFAKDLSTGRTI-EADADRVMGTASCIKLFILIELLRRVS -AGDLALGDRIAVHARQQVGGSGILKALSAGLMTLRDAAVLMMALSDNTATNMLIDLL-GL -ERINRTATELGCAHTRLINRIDFK--AIGGDITAVGTTRDFALALERIASGTLFYETASA -AALDILSCQLH-VDLLPRYLSQDLWVANKTGFFP-GFRGDVAIFTLPDRR-IVAAAFLDD -IE--------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A3D3Q7E7_9ACTN ---SLAVAIDAITAPTGTEIGVSLIELGAASSW-EVGGSQPMDAASTYKLPALMELAQLVA -AGKVDPAGQVCYQDADWED--GWFDDYTTGAYTRAELADRTAHYSDNTAGHMLVRDLGGG -DALNTYAAGLGAQNSAFF----D---------VNQTTADDLARLLAAEATGNAGGAQAQA -WLYPLLTNTEF-EAGIPAGVPAGTTVIHKTGELD-AQVNDAAIVTNGKNGTYVLAVMTNG -PGGD--AGSSLVAQVSAAVWAY- ->[subseq from] Beta-lactamase n=1 Tax=Moorella thermoacetica TaxID=1525 RepID=A0A1J5NHW0_MOOTH --tKLQQQIQNYLADKPGTYGIYFKDLATGQSF-GINADTPLPAASTVKLPAVLFINSLVD -RGILDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITVSDNIAYNMLRNFV-GQ -GSIASYMQSLGGRTVFP-------------SGQNLSTARDMATYIQAALDSAN-TSANGR -RLLDDMANGIY-NEGIPLQIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIVTVLSQG -VA-DPDQGFATVATVTRMMYDY- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Phormidesmis priestleyi TaxID=268141 RepID=A0A2W4X0Q2_9CYAN -----KAKLQGLPNTYGLSATVFYADVDTGDYV-DLSGGSAIAAASTIKLPILLAFFEEVD -AGRIDLNQAVAMLPEQIAEGSGDMQTQPGTQYTALEVVTQMIINSDNTATNMMIDLLGGA -EALNARFLGYGLEKTKINVPLPDLTGN------NTTSAKDLAHTLLLISQGNTLTMRSRD -RVLNILNRTYS-KDLLAAGMAQGALTYNKTG----------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI000480A7DF ------------LDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGHLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPTGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDHSRDEDACQLLADLSA--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPHIGHO2_02_FULL_40_18 TaxID=1798605 RepID=A0A1F6IUA7_9BACT -------VLEKFLKEEKGSYSIYYKDLSTGQEF-GINENKVLTAGSLNKLLIISYLYNLAS -DNKINLEDKITIQKKDIQDYGTGSLRYTGVGYTLKTLTQLALEQSDNTAAYVLSIRL-GE -DKIQEYGKKLGLTSTNMSN--------------NKTSAYDMGKILELIYSKKITSDSLTA -ELLDFMRDTDF-EDRLVRDIPSSVAIYHKAADSTN-MVHDVGIINDEKS-PFILAVLTSD -IK-DEEEAKKTIGKIAKFIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora musae TaxID=1894970 RepID=A0A3A9YKW2_9ACTN --------LDAHLDTVPGTVSAYVGRPDAEPAW-TRRADATHYAASTMKAAVLAALHRAAE -AGALDLDAPVPVVNSDSAQGAPRFWARVGGTAPLRWLAHRMIVRSSNLATNLVIGHV-GL -PAVAEVWSLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGALATGAIASPAACA -EMLDVLVAQEH-REDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAAPYAVVVCTTR -DAEDDADACALIADVSARVWS-- ->[subseq from] serine hydrolase n=1 Tax=Nocardiopsis trehalosi TaxID=109329 RepID=UPI0012F7AEE5 ----------------------------AGREV-AVRADERVVIASLAKILIALEFARQAA -AGQLDPTERVVATAADRLGGWGVAGYADDVEMSLRDCALSMMSVSDNTAADLVLRRI-GL -DTVQLLAEELGLVETRVIGGPRHLLEVFDPEHTSSSTARDITRLLALIWRDAAGPPEACA -AVRALMARQMS-WTRLAAAFPPGVRVAAKTGTLP-GLHIEAGVAEYPDGGRYAIAVFAAT -RSLDAR----------------- ->[subseq from] serine hydrolase n=1 Tax=Terrilactibacillus sp. BCM23-1 TaxID=2599694 RepID=UPI0012BD341A ------EKLDQLVSPFGNKVSVVIQ--GDQCHY-TFNETTKMLSASLIKLPILLYAFEQIK -KGNLSFSQKIRISSDNIVDGCGIIQVLHDVNWSIRDLLGLMINVSDNTATNVLMDVL-GI -EHIQAWINDHQLNGTSIQRKMMDMEAK-KEGKDNFTCAADITHCMELIFSSSNSLSHDFP -FIDNYFLNQQF-RGKLPGKIETPVKIYNKTGEMER-ISHDTAFIKLKDKR-AIVTCMTSG -FD-DSIEADQLIQKIGERVYLF- ->[subseq from] Serine hydrolase n=3 Tax=Clostridiales TaxID=186802 RepID=A0A3A9J428_9FIRM ------------------------------------------------------------- ---------------------------------SIESLINSMITVSSNDAFNTLFYKYLGK -GTVNKFCKANGYKKTQQYRPCGVGDES--GPKGNKTSAADCGMLLEKIYRGKMVSRAASQ -KMLNYLKRQTI-RTKIPRGVPYGIQVANKTGEDGT-IQNDVAIVYGKKT-TYIICVFSNT -NNPG--RAYNCIAEISRMVYN-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=UPI0009713EFB ---------EGIFSRAGVTGNLHVVDLDTGPEV-AVGADEQVVIASIFKILLVLEFARQVT -DGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLGRTRILGGPRQLVEVFDPERTTSSTARDITRLLGLIWRDEAGPAAACA -MVRGWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART -AQTRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Gottesmanbacteria bacterium GW2011_GWC2_39_8 TaxID=1618450 RepID=A0A0G0Q2B5_9BACT -------VIEEALEGTKGKYGVVIKNFQTGEEY-YANEHRKYEPASLYKLWIMATTFKQIQ -KGVLKLSEDIPVLNSKFHIDPTLAEQKEGKIMTVKDALEKMITISDNYSALLLSEKL-RL -SNVSDFLKENNFTESRLGE--PP-----------ISTPYDFAFFFEKLYNGELANEENTQ -KMLKILEKQTF-NGKIPKYLPDNVTIAHKTGEIGF-FTHDAGIVFSDKGN-YVIVVMSES -DSP--FGAEERISNISKAVYEYf ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. SM24M-10 TaxID=1660349 RepID=A0A0J1BU24_9MICC ---RLQADLQVLAAQVPGELGLVLLDPAGAEVV-SRNPDRPFTSASLYKLFLAHAVLDRVD -RGQIALTDTV-----------------PGTAFTVREAVERMITWSDNVSGAALGRWL-GW -HEVQAFAQGQGFESTTYDPDTGEAG-----TVAMTTTPDDVADFLDRLRTGDLLAEASTT -LLLGFLTAQEL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG -WSG-------------------- ->[subseq from] Beta-lactamase n=1 Tax=Candidatus Daviesbacteria bacterium GW2011_GWC2_40_12 TaxID=1618431 RepID=A0A0G0T495_9BACT ---NLKNAVENVLAGTKGTYAVAIKNLKTGESY-FANEHKSFEAGSLYKLWVMAAVLSKIR -DGTLSEEQVLSRDISALNEDSEVAELTEGKILSVNDALTQMITISHNYAALLLTEKI-KL -STVANLLKEKGFGESKVGRGDD----------VPHTTPYDIFLYFEKLYKGELAQPEDTE -KMLVLLKNQKL-NGKLPKNLPKDTVIAHKTGEIGW-FTHDAGIIYSDKGD-YIIVAMSET -DKP--AAAEERIARISESVYRYf ->[subseq from] Serine hydrolase n=1 Tax=Goodfellowiella sp. AN110305 TaxID=1892852 RepID=A0A5B2XDZ2_9PSEU --------IVGRADEVGVRVWLHATELDGPGRV-GIDATEPVVTASVFKVPVALELARQAA -DGELDLAERVTVAPGHPTAPYGLATFRHDVTMSWHDLAVLMIGISDNVATDLILARV-GK -DAVAESLRRLGLPGTAVPQDCGELLRALHPEHTCRTTAEEITRLLGLIWRDEAAPPAACA -DVRRWLELQVW-PHRLRSGFPDEIRVSGKTGTLPL-LRNEVGVVEYPDGGRYAVGVFTRA -VDSRVPERDAFIGFAAA------ ->[subseq from] Beta-lactamase n=1 Tax=Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) TaxID=479435 RepID=D2Q356_KRIFD ----------------QGDFGVWLGRLDGVPVF-MHAAERPHYSASTMKVLVAMAMLRKVD -AGELSLEQPVTVHNDFASAEAPATWTKLGEQVTLGWLATEMITRSSNLATNLVLEQA-GV -DTAQAVLAEYGSGASAIQRGIDDVAAQ-AAGISNLMSPADLAAVLVAAGNDD---SASGR -YLRDLLAANEW-NGEIPAGVPAGTRVEHKNGWDVR-IRHDGGIVRPADAEPFVLTVCTTS -ELP-DPDAQKLIAAIAAEAWNH- ->[subseq from] Beta-lactamase n=1 Tax=Amycolatopsis lurida NRRL 2430 TaxID=1460371 RepID=A0A2P2FKP2_9PSEU ---EVSETINERAKEAGVRVRLHAAEIDGTRRF-GVDEHAPVVTASVFKVPIALELAKQGA -EGGLDLGERITVPPGHPTPPYGLATFRHEISMSWYDLAILMIGISDNVATDLILDRV-GK -ESTEKTLRGLGFEHTTVPQDCGETLGALQPEHSCATTAEEITRLLGMIWRDEAASPTACA -DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEAGVVEYPDGGRYAVGVFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N6XT66_9ACTN --------VEGIFSRAGVTGNLHVVDLDTGPEV-AVGADEQVVIASIFKILLVLEFARQVT -DGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GP -DLLPMLAAELGLGRTRILGGPRQLVEVFDPERTTSSTARDITRLLGLIWRDEAGPAAACA -MVRGWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGGRYAIAVFART -AQTRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Terracidiphilus gabretensis TaxID=1577687 RepID=UPI00071B9173 ---SLDATLQSIAAAHHGKVALYAENLRTHQVA-SITPDLPVQTASTIKLAILLDAAEQIR -AGKASFDEKLVLSHENQVPGSGIIGQLDTPLLTLRDVLHLMVTLSDNTATNMAIDRL-GL -DHINQTILAAGLHQTWLYKKVYKPASDQPKFGLGKTTPREMAEIMTRLVTCNLAPLATQE -TFHVVMPDSASIDGPIRDGLPQGTAIGNKTGALDR-VRADVAIIASKSG-PIVIAAYTFE -NQDQDNEGKITLAKIGEAIVKAw ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ295 TaxID=2512146 RepID=A0A4Q8A751_9ACTN --------LDARLDRVPGTVSAYVGRLDAAPTW-TRHPDATHYAASTMKVAVLVALHRAAE -AGRLDLDGQVPVRNESALPGAPRFWDRVGGSAPLRWLAQRMIVRSSNLATNLVIGHV-GR -PALADVWARAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGALAFGALATPPSCA -AMLDTLAAQEH-REDLAAGLPDGTRVAHKNGWVR-GVRHGAGVVYPDDAPPYVIAVCTTT -DLADDDDACHLIADISRAAWT-- ->[subseq from] Peptidoglycan-binding domain 1 protein n=1 Tax=Candidatus Woesebacteria bacterium GW2011_GWB1_43_14 TaxID=1618578 RepID=A0A0G1DMM8_9BACT ----IESRLEGMVSGLSGVYGVYIVRLDSGESY-GLMKDEIFQAASLIKLPAIAGIYMEAD -QGNINLNDEVAILEEDRVGGSGSLVGAPAGSYSYRELVNYMGNQSDNTAFRMVRRTL-GD -EKINDVIVSLGMTHTSLENN--------------ETTPEDIANFFTLLFEGKITSSRRAK -EIVDALTNTSY-EEWIPAGIT-GYSVAHKYGREVH-VVNDAGIVFSD--EPFVLVIMSKG -VVE--TEADKIIPELAKEVFEY- ->[subseq from] Serine hydrolase n=3 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PK95_9CHLR ---DLASALDQAAAGVPGMVSVVVVDLDSGYVY-ERRADERVEAASLFKLFVMAALYRRAL -DDPQLFEATVPVSRPRLTAGQV---DYALEPVAVREGLEAMIDWSDNEATAALVELL-GT -DEVNATIASLGLRDSVVRSGEASGN---------STSARDIGRFLTLLARREIVSPEASD -AMTWLLLRQGI-NDRLSLGMPKDALFAHKTGNSA-GTFHDAGIAWTAWGE-RVLVVLTDG -VA--APDARALMKDLGYW----- ->[subseq from] Beta-lactamase class A n=2 Tax=Kribbella sp. VKM Ac-2571 TaxID=2512222 RepID=A0A4R6KY26_9ACTN -----NARIRGIFEDAGVRGWMHAISLDDPQASvELDADVVVPLASVYKLPLLAGFCRLVD -LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL -RRLAEILESFGLRRTWVRRGTAGNLRVYEAANGSAASARDLTLLLRRLWAGELLSASQTE -FVKTTMHRQVF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Beta-lactamase related protein n=1 Tax=Amycolatopsis azurea DSM 43854 TaxID=1238180 RepID=M2NS50_9PSEU ---EVAETINTRAKEAGVRVRLHAAEIDGTRRI-GIDEHAPVVTASVFKVPIALELARQGA -DGELDLGEPVTVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK -EPTEKSLRRLGFEHTTVPQDCGEVLDALQPAHTCATTAEEITRLLGLIWRDEAASPAACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=Agromyces sp. KACC 19306 TaxID=2592652 RepID=UPI00143D1344 -------EAARVLDDAGLTASILVRDLATGREL-AHRADAPYPLASIVKLPLALAVLRAAE -TGDLDLAEPVRLDPGRRTPPTGTCRFEYAAEIAIGDLLSLAMCVSDDTAADALFDRC-SP -DAVTAVLREVGVEGITVRHRIRDLHEQLDVTGANAGTARALVDLLERIWGDPALA-RERE -PLRRLLSGNLVRQRLAPDLESDDAEWFSKTGTFLH-LRHEVGVIEHRDGGVFAIAVLSES -SVQRQPAAEQALGAAASLL---- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A2E0S076_9CHLR ---ALRSNVLGIIDEFSGTASVSANNLTTGDLL-DINEKEVLPALSAIKIGIMAELFFQIE -DGKYNLLDRVTVNASDLRGGTGVFREMETPLVTLKDLCMMMIVVSDNTCTWMLSSML-GL -DAINQRMRSLNMNEYSLNHDLPTAFDDMQGDAYSECSARDFTTLVTLMAKGELVSKTSSD -AMLDIMGRCQH-IEWLGRYLPPKVKLYNKLGAYLH-ARCDTGLIKSENSD-YVITVFASY -SKDEPHEGSRLIGKVSKAVYDAw ->[subseq from] Serine hydrolase n=1 Tax=Planctomycetes bacterium TaxID=2026780 RepID=A0A538RT92_9BACT ------------------------------------------------------------- ---SIKLTDPVTLREEDKVPGSGVLTHYFSAGFPLKDAVRLMIDVSDNTATNLVLDKI-GI -ASTGKRMAAWGFPETKIHAKSFRGSTRSKRYGLGSTTAREMVGILEKLQRGKAATPEGCK -EMLAILQQCED-KEKFPRFLPEGVKVAHKTGSLSD-ARTDAGILSWPAG-PVALCMLTNN -NEDHDNAGNVFCAKVAREVYDYf ->[subseq from] serine hydrolase n=1 Tax=Kocuria sp. UCD-OTCP TaxID=1292021 RepID=UPI00123756D1 ------------------------------------------------------------- -----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHEQGFTDTTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Beta-lactamase-like protein n=1 Tax=Amycolatopsis azurea TaxID=36819 RepID=Q6WSB4_9PSEU ---EVAETINTRAKEAGVRVRLHAAEIDGTRRI-GIDEHAPVVTASVFKVPIALELARQGA -DGELDLGEPVTVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILARV-GK -EPTEKSLRRLGFEHTTVPQDCGEVLDALQPAHTCATTAEEITRLLGLIWRDEAASPAACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVQYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Propionibacteriales bacterium TaxID=2015801 RepID=A0A6A7MLE7_9ACTN --------------AVGGEVSVWCGRADGTPVW-TRLPDQQHYAASTMKLPVLVAAHRRAA -AGGLDLDAAVPVHNEFASVGSAYSWDAIGTSRPLRWLTQRMIVRSSNLATNLVLDQV-GV -PAVAEALDACGSTATTVARGIEDYQAR-DHGLDNMVTAPGLAAVLVTLVAERAADPAACK -EILDVCAANEW-NDGIPAGLPAGTRVSHKNGWQNR-VCHDAALVQPADAEPFVLVVLTTT -DL-ERSAADALTARIAAAAYT-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2D6R0B9_9BACT ---RLERAIERGATVAGGLVGATAIHLESGRTV-SVNGDEAFPMASTYKVPIAIELLTRAD -AGTLSLDEMLDVMAADLHPGSGTLSPLLAQPLSVRNLMELMLRISDNSATDMLLARAGGS -EAVTGRMRMLGIDGIRVDRPTAVLI----------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=A0A328NH39_9ACTN -------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVVVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535NWA4_9CHLR ---RLSADLALIAGTSGGRVGISLQELSGPRSL-SVNGGQSFVAASTYKLPLLMAEAQQIA -SGQARPSDLLCYAPGDAEDG-WFTDYQPGSCFTRDQLALRTGRYSDNTAAHILVRYLGGA -DALNRYAKSMGMTNSAL--WT-----------PNTTTPDDLSQALVSEALGRLGGAAAQA -WLYPILTHTAT-ERAIPAGLPAGVTVAHKTGSMP-GTENDAAYVRNG-RIAYVLSITVDG -LD--EGTAWSLMARISARVWQY- ->[subseq from] Beta-lactamase class A n=1 Tax=Humibacillus xanthopallidus TaxID=412689 RepID=A0A543HWK5_9MICO ---DLVARLDALASDDSASVSVWLGDLAGRCRW-SHRADAPHYAASTMKLPLVIAAQRRVV -RGELDLDAPLPVRNASVLDGSPFTWAAVGATRTLRELAEHAITHSGNLATNLLLDVV-GR -DEVAEVVRLAGCSPTVVGRGIEDAVA-RAAGITNTVTAADLGLLMAAVARRELGGPPVCE -PVEQILERQQH-VDQIPAGLPSGTPTASKSGWIP-GVSHDVALVRPAGEDPFVLSICTTI -EL-GEHEAAAFVASVAADVW--- ->[subseq from] N-acetylmuramoyl-L-alanine amidase n=2 Tax=Streptococcus sp. DD10 TaxID=1777878 RepID=A0A139NA43_9STRE ------NEYNRLFGNIGGQKSLYISP-VDGTEY-RLVNDSVQPSASSIKLFVLAAAYAKAA -RGELNLQQRYTVQQSDIIPNQAVTLNLYGKAYNLDQLLHFMTSTSDNSATNIIIRHIGGV -DAVNNEIRRLGYNHSTLNRYMYDSA-AISRGVDNYISAQESGDLIKNIYNGTLIDKATDA -AILEKLAHNVH-NYWLTANIRDKAQLWEKPGGSGSGTENDTAIIKKNNRA-YAVSLLTYG -ATNQNSA---------------- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. WP24 TaxID=2604469 RepID=A0A5D0TC52_9ACTN --------LDAHLDTVPGTVSAYVGRPDAEPAW-TRRADATHYAASTMKAAVLAALHRAAE -AGALDLDAPVPVVNSDSAQGAPRFWARVGGAAPLRWLAHRMIVRSSNLATNLVIGHV-GL -PAVAEVWSLAGARHSVTGRGIEDFAA-RDNGITNLVTAADLAALLGALATGAIASPAACA -EMLDVLVAQEH-REDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAAPYAVVVCTTR -DAEDDADACALIADVSARVWS-- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI0011B22814 ----LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA -LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Beta-lactamase n=2 Tax=Bacteria TaxID=2 RepID=K2CUN5_9BACT ---NLKNAVENVLAGTKGTYAVAIKNLKTGESY-FANEHKSFEAGSLYKLWVMAAVLSKIR -DGTLSEEQVLSRDISALNEDSEVAELTEGKILSVNDALTQMITISHNYAALLLTEKI-KL -STVANLLKEKGFGESKVGRGDD----------VPHTTPYDIFLYFEKLYKGELAQPEDTE -KMLVLLKNQKL-NGKLPKNLPKDTVIAHKTGEIGW-FTHDAGIIYSDKGD-YIIVAMSET -DKP--AAAEERIARISESVYRYf ->[subseq from] Uncharacterized protein n=1 Tax=Kutzneria albida DSM 43870 TaxID=1449976 RepID=W5W878_9PSEU ---ELIRTITDRATEVGVRVRLHAVDLDGSRQV-GIDATTPVVTASVFKVPVALELARQGA -VGELDLAEQVRVAPGHPTAPYGLATFRHAVTMSWYDLAVLMIGISDNVATDLIMGKV-GK -SAVASLLRRLGFAHTAVPQDCGELLRALRPEHTCRTTAAEITRLLGMIWRDEAAPAAACA -DVRRWMGLQVW-PHRLRSGFSDEVRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGVFTQA -IDSAVPQRDAFIGFAAERAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_41_10 TaxID=1802500 RepID=A0A1F7YLR1_9BACT -----IAAFEDTTRGLSGVYAFYVYDLTSGVSY-GIHQEEMFQAASLIKLPVLAALYMESE -AHRIQLTSEYSLREEDKIGGSGSLQYAEEGSYTFAELAELMGKESDNTAFGIVRNRL-GD -KKINSVIDTLGMHDTSLS--------------ENQTTPSDIGRFFRKLWEARLISRESRN -EILDHLTDTIY-ENHLAAGIPDDVPTAHKYGREVH-IVNDAGIVLSEN--PFVVVIMAKG -VVES--EADDVFPTLSTLLF--- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium ulcerans 12-1B TaxID=457404 RepID=H1PRI9_9FUSO -----EERIKKIIEENSGVTGVIIRD-SSGKMI-TINEEVVFPSASIIKLFILMALNKD-- -----EYNKKIELKKEDKVGGCGILKVMGDGLLTVKDAAYLMICLSDNTATNILIDYI-GM -DKINECIREKGFTGTVLGRKMMDAEAR-KAGKDNFTTPKDVLGVLEMLCGN----PD--- --DLDMLRNQAY-NNKIPLYFAREVDFAHKTGELMY-IEHDTGRLFYDGG--WVDVIVLTK -DLEKNEDGIKINSLIGKVIFDNy ->[subseq from] Serine hydrolase n=1 Tax=Clostridium sartagoforme TaxID=84031 RepID=A0A4S2DID2_9CLOT ------KEIKKYLESRMGTYGFFFEDLKSGFIY-GYNENVQITAAGCMKLPIAVSLIKAVE -DKKHDFLDKIKIESKDKVYGTGIIHEFSEREYTLFELLVAMLIQSDNTAANKIIDIL-TM -DKINEDIKGMGLRNTVLNRKTTDERNA-KDEIENITSALDLSKIWKHLYNGTYLNRENSQ -MLIDILMRQQI-KNKLALYIPDDYEISSKTGDKA-GVENDTQLIRLSKGN-FSFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] serine hydrolase n=1 Tax=Plantactinospora sp. BC1 TaxID=2108470 RepID=UPI000D16ED9C -------------AALPGTVSVYAGRLGRRPAY-TRLPDTPHYAASTMKVAVLAALYRAAE -AGEVELDAPVPVVNEFDSAGAGRFWARVGGTAPLRWLAERMIVRSSNLATNLVLGHV-GL -PAVAQVWADSGARHSHTRRGIEDFAA-RDAGLDNQVTAADLARLLGGIARSRLASPGACA -AMLDVLLAQER-GEDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTSA -PPDRDARARRLVARVSALVWA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. 4121.5 TaxID=1938847 RepID=A0A2N0EI76_9ACTN -------------------------------EF-GFRADEPSVPASVVKVQVALEVETWFA -EGRLDPGERVTLSAADRTPGPTGTSLFEDDVLSWRDMVVLMLTISDNHTTDVLLRRI-GV -AAVNATAERLGLTGTVLESDLRTMLDALDPSRGTRTTPRDMAELLRLIWTDRAGPAAACA -RVRTLMGHQLT-RHRIASGFRPPVRVAAKSGGLLGVVRNEVGVISHPDGRRYAAAVFTRS -RPSDETAINAAIGAAARAV---- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7A0L4_9BACT ---DLVKRLNELSDSAEFEVSWYLRDLASGATA-NRRGDVAVPSASTRKISIMMAALAAVH -AGKLALDQKVTIDARFQDNDSGTFQHLTPGFITLRDAMVMMIIVSDNTCTGHVVDLV-GL -ANVQRYTETVGLTGTVHRYGIPKTGADNTLDRVTTTTANDQGLLLELILKGTACTPALCR -LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKEERPLCVLTAYTVG -VPPGFAAAYQLIGRMARMS---- ->[subseq from] hypothetical protein n=1 Tax=Candidatus Syntrophocurvum alkaliphilum TaxID=2293317 RepID=UPI0012E2DDC1 -------KAAEEAKKSDNRLRASVYDFATNTTV-NYNGNQRFYPASLTKVLNLLCYLEEVE -RGNKYLNSTYKLKESDKYIGTGSLQHQEEGTYTFDRLLSLMISISDNVASNIVLDAL-GT -DRVNSFAVRHYLNDTRVFRKFYDFSTN---KSYNYSTTVDLTRKLVLLENRQVVSDYLSS -KGISFLEDTAD-KNKIGRYAPDNVVVANKIGVLSR-MSGDMALVYFPHREPIALTIVIED -KERELEEADKIIGTLSKELIDYy ->[subseq from] Beta-lactamase class A n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=A0A2T0R7V4_9ACTN ------------------EVTFWAEDLFSGRGA-RHRADEARPVLTLSAGLALGLLLS--D -RGPHALTGRVRYSATQLVRSSPVCAWHVQDGLSVAQLGDAALRRADATATNLLVARAGGA -AALTAFCRRLGDRRTRVDRAAPDSCTGAPWDPQDTTTTAALARTYGALLLGRALAPGARS -QLLDLLPTT---------GLTGGWAVTHAVASGRYGTAALVGTARRGRR-QVLVAATVRA -GQPA------------------- ->[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium GW2011_GWA1_48_10 TaxID=1618496 RepID=A0A0G1U677_9BACT ----IQNYLQAETGKLPGNYCVYIKDLKRGATY-KVNANQPLATASIYKLAVMYKTYDAIN -RGELKKEDVLTEDESTLDQLKPEADTNTSGTYMVADALRAMITVSDNYSALLLADKL-GW -KNIDDFLKQQKIEGFDLV-----------GGQQPTATAEAVAILLERIFRNTAVNSQSSE -EMKGLLLAQQV-NDRIPKYLPKDTKVAHKTGELDN-FRHDAGIIYGKNST--YIFVFLSE -TPAPG-DAVENIANLSQKMY--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. KC207 TaxID=2530377 RepID=A0A4R4SBW0_9ACTN -------ELDARLDALPGTVSAYAGRVDAPPTW-ARRPDATHYAASTMKVAVLLALHRATE -AGTLDLDAPVEVRNESALPGAPRFWEREDGHVPLRWLAERMIVRSSNLATNLCLRHV-GL -PAVADAWAIAGARHSVTGRGIEDFAAR-EAGITNLVTAADLAALLGGLAAGALASPAGCT -AMLDVLSAQEF-REDLAAGLPDGVRVAHKNGWVR-GVRHGAGVVYPPDAPPYVLVVCTTG -DPAD--DTCRLLADISARVWA-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. NRRL WC-3626 TaxID=1463926 RepID=UPI0004BF9893 -----------------------------AREV-AVGADDAVVIASIFKILLVLEFARQVV -AGQLDPRERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLGRV-GL -DTVGLLAKELGLDRTRVVGGPRDLLDVLDPHHTTASTPREITRLLRLVWTDAAGPPEACA -LVRDLMGRQVF-RHRLVSGFPDDVMVAAKTGTLP-GLHMEAGVAHYPDGERYAIAVFART -HDASRATVDAAIGRAAG------ ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBFE019 -------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Beta-lactamase class A n=2 Tax=Kribbella sp. VKM Ac-2566 TaxID=2512218 RepID=A0A4R8DKT0_9ACTN -----NARIRGIFEDAGVRGWMHAISLEDPQASvELDADVVVPLASVYKLPLLAGFCRLVD -LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL -RRLAEILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRRLWAGELLSASQTE -FVKTTMHRQIF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rhizophila TaxID=72000 RepID=UPI0011A67959 --------------DMTGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD -RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH -ARVWDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA -FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS -VRRQIAVSNRIVGQIARHCVRSy ->[subseq from] serine hydrolase n=2 Tax=Kribbella sp. VKMAc-2574 TaxID=2512112 RepID=UPI0010648FD3 -----NARIRGIFEDAGVRGWMHAISLEDPQASvELDADVVVPLASVYKLPLLAGFCRLVD -LGELDPRERVTLEPSARTAGPTGLSAFADPVVSLRDLALSMATVSDNASADALLDIV-GL -RRLAEILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRRLWAGELLSASQTE -FVKTTMHRQIF-LHRLASGFPDGVRVAGKTGTFG-ALRHEAGVVTLPGGAAFAIAVLTLA -ARGDQPRVDAAIGEAARVAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Sporolactobacillus sp. THM7-4 TaxID=2511170 RepID=A0A4Q4IFD4_9BACL ----FINKLKSLTEPLGDQIAIAAEG-SDGFRF-LYNESVPMLSASLIKLPVLLYVYDQAK -IDRSILKKTIVLRNHEIVGGSGVLQILSGREWSVRDLLALMINVSDNTATNLLIEEF-GI -RPIQQWVREHGYKETTLERKMMDTAA-EDAGKRNLISARDACQAIRTLFSDQ---KAYPD -EIKSWFLHQQF-RGKLPGEVPNPVSVYNKTGEMEE-IDHDAAFFSYKSS-SMSIAVLTSG -VK-DRQIALSVIQKIGKSVSDY- ->[subseq from] Beta-lactamase protein, beta-lactamase n=1 Tax=Microgenomates group bacterium GW2011_GWC1_39_7 TaxID=1618515 RepID=A0A0G0PGJ3_9BACT --------IGKFLKTIKGTYSIYYKDLKTGEEF-GIDENKVLTAASLTKVLIIAYLYNQAN -KGKINLEDKIVIQKDDIQDYGTGSIRYEGEGYSLKQLIKLALEQSDNTAAHVLVLKL-GE -GKVQEFGARLGLAATNMKN--------------NKTSAQEMGRLFELIYLKKITSEPLTR -EFLDFTKDTDF-EDRLARDLPSNVAMYHKAADATN-MVHDAGIIDD-GKNPFILSILTEN -IA-SEEEAKKNIGKLAKFIYDQ- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum terrychapinii TaxID=2290919 RepID=A0A398D1A7_9BACT --------------------------TEDRCLIfSQNSNLPFGAASIIKLPLLVCVAQLVE -LGELAWDRAIRLTVAAP-HGTGLLEYLDKSGWSVQDLCIMMMGVSDNMACNQLIEEI-GI -ERLNDVLHDLGYEATSIRRQMMDRET-LARGIDNSVTAADIADMLARLHAHRLVSNAASE -RILGYLRMNQL-RDLVAWPLPGSAALAGKTGGMS-GSLLDAELITVSGGPTYSLCVFASG -FE-RAAQAKRVMAEVSEMIYS-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DBFA224 -------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHTTSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium HGW-Chloroflexi-9 TaxID=2013732 RepID=A0A2N2LEC2_9CHLR --dALAARLNALADEAPFHIGWHLTDLRTGASA-DRNGGVVVPSASTRKVAILLEALRGLH -EGRFDLERRITVDELVKTTSGAFQWFRPGFTVTFHDLLLMMIIVSDNTATGLVTGMV-GL -DRVQALCDRIGMTGTAHRRATPDYSRDPGPGVTNDTTPNDQGRLLVAILEGAGVTPDLCA -YALDLMSKQRL-RTRIPSWLPEDVKVANKTGSLG-GNHNDVAVVYEGDE-PLFVFTYFAD -H---------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Gemmatimonadetes bacterium TaxID=2026742 RepID=A0A2V7GN38_9BACT ------------------------------------------------------------- ---------------------------RVGQKASVRDLLELMITVSSNLATDILIERV-GP -ARANATAHALGADSILVLRGVEDGV-AYRAGRNNTTTARDLGALLAAIAEHRAASRVACD -SMLAILGRQHF-TEGIPAGLPPGARVYHKTGWVGQVVYHDAAYVEMPGGRRYVLVVTTGG -IQLD-TAAYHLVADVSRIIS--- ->[subseq from] Beta-lactamase class A-like protein n=3 Tax=candidate division WWE3 TaxID=422282 RepID=A0A0G1DCW5_9BACT ---KVETQFVELTKKLPGVYGLYIKDVGSGREF-KYNDATEFYAASLYKVPLAAAVLKEVE -AGKLKLDDTATYLPYDYSSGTGVISTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY -KNVQETFNAV-----VPDKNTSTYY------RYNLSTPAEISFVFEKLYFGDYLNAEDKK -YLSDLMVNTSF-EDRISAYLKDGLVFSHKIGSWPD-SWHDCGVVSSEANSKLIVCLMSQK -A---------------------- ->[subseq from] serine hydrolase n=1 Tax=Kitasatospora azatica TaxID=58347 RepID=UPI00055EFDA2 -----TDKISAVFEQAGCEGTLCVQSLDGGAEV-AVRADQQAVLASVSKVLIALEAESCFA -DGRLDPGERVTLGAVGRTPPTGISLLQDDVVLSLRDMVVLMLTISDNHTTDELLRRI-GV -DAVNAMAARLGLTSTVLESDLQTMLDALDPAKGTRGTPRDLVRLLRLIWTDQAGPAAACE -RVRGIMAKQLT-RHRIAAGFRRPVQVAAKSGSLIGVVRNEIGVISYPDGRKYAAAVFTRS -RPADEFAINAAIGSATARA---- ->[subseq from] Serine hydrolase n=1 Tax=Kocuria indica TaxID=1049583 RepID=A0A4P6RMB4_9MICC --------------DMTGAVAVRVIDAPELPAF-GWRADEAFPAASLYKLVVMVAFCRAVD -RGDLDPTALVTLRPEDRADPTGLAICQDPVRISWRDLVRLMMTVSDNAAGQAVLREV-GH -ARVWDVLREMGLSSTVVRPG-PAPDAGYDPLLVSATTASDLVALLCAIWQDRAASTAQCA -FMREVMSQQAWGHRFAEAFSYPGAGVAAKTGSFG-ALCHEAGVISHPGEKSIAVAVLTRS -VRRQIAVSNRIVGQIARHCVRSy ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0003700992 -----------HLDRMPGTVSAYLARLDAAPTW-TRRPDTTHYAASTMKVAVLVALHRALA -AGRLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLRWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPERCT -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDHSRDEDACQLLADLSA--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora echinofusca TaxID=47858 RepID=A0A1C5G6U3_9ACTN -------ELDARLDGVPGTVSAYVARVGAAPAW-TRHADATHYAASTMKAAVLVALHRAAE -AGTLDLDAPVPVRNESALPGAPRFWERVGDDVTLRWLAHRMIVRSSNLATNLVIDHV-GL -PAVARVWDLTGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT -DLEEDDDACRLIARVSAAAWD-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01416 TaxID=2203196 RepID=A0A429C7G6_9PSEU ----VIETINDRAKEVGVRVRLHAAEVDGTRRI-GVDEHTPVVTASVFKVPIALELARQAA -EGGLDLGERIAVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -ESTEKSLRRLGFEQTTVPQDCGEVLGALRPEHTCATTAEEITRLLALIWRDEAAAPVACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTEA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6Z743_9BACT ---DLVKRLNELCDAAPFQASWYLKDFATGASA-DRRGDVPVPSASTRKISIMMAALAAVH -AGKLALDQKVTIDARYQDNDSGTFQHLTPGFITLRDALVMMIIVSDNTCTGTVVDLV-GL -PNVQRYSESVGMTGTVHRYGIPKLGPDNSLDRVTTTTPNDQGLLLELILRGTQCTPALCR -LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKADRPLCVLTAYTMG -VPEALA----------------- ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A2V1MAT1_KOCRO ------------------------------------------------------------- -----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA -LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Beta-lactamase class A n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A2H1IZ67_9MICO ---RLTREVSDELEAAGLRARIVVRDLDSQAEI-SIAHDGPVPLASVVKVPIALAILNRIA -DGRLEADRQVHVAPGRFEGGSPMGTSRFRHPIAVDDLLMLSVCFSDNTATDALLDLV-PT -EEVQRDLDDLGLGGIQIRHHLDALVRQLDVSQANVATAAGLTDLLAELWRPERIQTSAAS -RLRELMAGNVVRHRLAPDLMSDAAKWSSKTGTLLH-LRHEIGVVEHSDGQTIAVVVLSES -SNAVQPAAEAALGAAARALH--- ->[subseq from] Beta-lactamase class A n=1 Tax=Bacteroidetes bacterium HLUCCA01 TaxID=1666909 RepID=A0A0P7WGD0_9BACT --------FRNIESLLEGTLHVAAIEVQSGKTW-SYQSDTPVSTASTIKLPILIHTAMQAG -NGELAWDSQIPVQKDDLVGGMGVLRHHTPGTVRLDDACYLMTSLSDNTATNLVLDQT-GI -EPVNESLNIFGCANTRLYRKVPDTPES-MEFGLGVTTAADMLRIMQLLYAGVSLPDERAV -EFCKTMLDLQQDRVGVARIVPDAWTYAGKTGRVTS-TRGEAAMVSAPDGRMWLLGIFVHG -LT--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chokoriensis TaxID=356851 RepID=A0A1C4X0P4_9ACTN -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAE -AGTLDLDAPVAVVNED-SAGAPRFWDRLGATATLRWLADRMIVRSSNLATNVVIGHV-GL -PAVADVWASAGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALASGAIASPAACA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGVGVVLPDDAPAYLIAVCTTT -DPDDADDACLLIADVSARVWA-- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Arsenicicoccus sp. TaxID=1872639 RepID=A0A2W6V2N0_9MICO -----------------------------RHEV-SYAADDLVPMASLYKVLLALAWARLVD -AGDLDPRARHTVSAPDRTPGPTGLSSLEDEVVSQRDLVTLMLTVSDNAAADVLLDLV-GL -PRLREVAADAGMTATTLHGGTRHHQRVYDPAMSSTTTARDMTRLLGALWREELVAPESGA -RIRRSMARQVF-RHRLASGFPDDVEIASRTGSLLT-LRHEVGVVTFPGEEPVVVAVLTQ- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Agromyces sp. KACC 19306 TaxID=2592652 RepID=A0A5C1YCQ3_9MICO -------EAARVLDDAGLTASILVRDLATGREL-AHRADAPYPLASIVKLPLALAVLRAAE -TGDLDLAEPVRLDPGRRTPPTGTCRFEYAAEIAIGDLLSLAMCVSDDTAADALFDRC-SP -DAVTAVLREVGVEGITVRHRIRDLHEQLDVTGANAGTARALVDLLERIWGDPALA-RERE -PLRRLLSGNLVRQRLAPDLESDDAEWFSKTGTFLH-LRHEVGVIEHRDGGVFAIAVLSES -SVQRQPAAEQALGAAASLL---- ->[subseq from] Uncharacterized protein n=2 Tax=Saccharothrix espanaensis TaxID=103731 RepID=K0K8V2_SACES ---EVVREIRSRAEEVGVRVWLHAVEVDGTREL-AVDADDPVPSASVFKVPVAVELARQGA -AGEVDLGERITYVAGTGTMPFGLATYRHDVTISWHDLAILMIGISDNVATDLVVDRI-GL -PSIARLLAELGLKHTAVPFHCDGLFQILQPAETCRTTAEESTRLLGMVWRDEAAPAQACA -DVRNWLGHQVW-PHRLRSGFHEGIRVFGKTGTLPM-VRNEIGVVEYPDGGRYAVAVFTQA -HDAQAPERDGFIGFAAARA---- ->[subseq from] class A beta-lactamase n=1 Tax=Kineococcus rhizosphaerae TaxID=559628 RepID=UPI000D0667B4 ------------------EVTFWAEDLFSGRGA-RHRADEARPVLTLSAGLALGLLLS--D -RGPHALTGRVRYSATQLVRSSPVCAWHVQDGLSVAQLGDAALRRADATATNLLVARAGGA -AALTAFCRRLGDRRTRVDRAAPDSCTGAPWDPQDTTTTAALARTYGALLLGRALAPGARS -QLLDLLPTT---------GLTGGWAVTHAVASGRYGTAALVGTARRGRR-QVLVAATVRA -GQPA------------------- ->[subseq from] Serine hydrolase n=1 Tax=Plantactinospora sp. BB1 TaxID=2071627 RepID=A0A2R4FTY4_9ACTN -------------AALPGTVSVYAGRLGRRPAY-TRLPDTPHYAASTMKVAVLAALYRAAE -AGEVELDAPVPVVNEFDSAGAGRFWARVGGTAPLRWLAERMIVRSSNLATNLVLGHV-GL -PAVAQVWADSGARHSHTRRGIEDFAA-RDAGLDNQVTAADLARLLGGIARSRLASPGACA -AMLDVLLAQER-GEDLAAGLPPGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYALVVCTSA -PPDRDARARRLVARVSALVWA-- ->[subseq from] Uncharacterized protein n=1 Tax=uncultured Ruminococcus sp. TaxID=165186 RepID=A0A1C6KGS0_9FIRM ------------------------------------------------------------- ---------------------------------TTKHLLDEMITVSDNSATNELVRYLNGM -KKVNAFIKAQGFEYTHEYNGLEDTSLWYDTDTKNTTSAKDCGRLLERIYRGEFVSHLASR -QMEELLLNQQV-TYKIPSTIPSESRVANKTGETSD-CENDAAIVYTPKGD-YILCIMSCE -VS-SKNSAVDSLQEMSSLIYSYf ->[subseq from] Beta-lactamase n=1 Tax=Ruminiclostridium hungatei TaxID=48256 RepID=A0A1V4SG80_RUMHU ---ELKKLITDYTSKLSGKYGVTYIDLATGEMV-NVNDQIEYIAASTSKLPINMVLFKDIE -AGKVTFDEKLVYKQEDMEPGTGIIQSSAYGTYTVRKTSELSIKKSDNCGVNMIIRRV-GI -ENVRQYLVDLGGKVYY--------------GKTHRSCPYDMALVAKDLYIHYLNNETVFG -ELINNMENTNW-SDRIDAKLPQEVKVAHKIGNQTK-TANDVGIVFAK--HPYVLSVMTDN -VD--FGTACNNIAGLSKKIY--- ->[subseq from] serine hydrolase n=1 Tax=Halorussus salinus TaxID=1364935 RepID=UPI00109334AB --dELAEYVESYADRIDGRLGVFLGFPREFDAVvERNAATAFAAASVIKLPLLYALYDEYD -GRLAELGERREIAPRNRVAGSGLYHLLDSPDPSVEDLARAMIAISDNAATNELIDLL-GM -ERIEETAADLGMARTRLRRKMMATVGWPEGEPANATAPADCARLFADLIHRATLSEAAYD -RLAVPLREQKH-AMLFPRYFPMDVECVHKTGQLPS-AALDAGYVEPPGKA---------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Micromonospora noduli TaxID=709876 RepID=UPI000DC04A33 -------------------------------EV-GVRADEQVVIASIFKILLVLEFARQVE -AGQLDPTERVLVTAADRLGGWGLAGCDDDAEVSLRDLAYFAMSVTDNTAADLLLRRV-GP -DLLPMLAVELGLTRTRVLGGPRELVEVFDPAHATSSTAREITRLLTLIWRDEAGPAAACA -MVRTWMARQIF-WTRLAAGFPPGVRVSGKTGTLP-GFHLEAGVAEYPDGGRYAIAVFARA -EQPRRIDVDLAMGEAARTAV--- ->[subseq from] Serine hydrolase n=1 Tax=candidate division WWE3 bacterium TaxID=2053526 RepID=A0A3A4ZAX6_9BACT ---KLIETLKNELNQLEGHVALKVKFLNTGDIF-EHNPDLQLWAASVIKVPIACEFFRQVS -ESKFDPQTRIMVSEDNFVDAAGVIKHLSRDIYPAIDLVKLMLIVSDNSATNQIIDLV-GW -ESIEKYTQELGLRDTTFRHKMMI--K--AGRGPNLTTANDMTSLLEMLYNHKL---SGSQ -EILDYMNEQLD-RTRIALYLPNDIKVPRKYGSLPE-AMHEVGVVYSK--SPFIFSFLSDD -Q-KDKRMTNEILSKCAKYCFD-- ->[subseq from] Uncharacterized protein n=1 Tax=Deltaproteobacteria bacterium 13_1_40CM_3_69_14 TaxID=1805116 RepID=A0A1Q7M103_9DELT ---------------------VSFHDLETGERI-ELRARESVHAASTMKLAVLLAAYRLG- ----LPLDQPVRVENRSIADGSTFAYTQLGKEVPLQVLLEHMIVRSSNLATNLVMLKL-QA -AQVERVCRDLGANDIRVLRGVEDLKA-HEKGLDNTATAHDLALLLEAMP------PP--- --AVEILSRQEL-NEGLPAGLPKGTRVAHKTGEIDR-HYHDAGLVFPPGRKPYVLAVMTRG -FE-TKEEAAAVVREISRTVWR-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. WAC 01376 TaxID=2203195 RepID=A0A428XKZ5_9PSEU ----VIETINDRAKEVGVRVRLHAAEVDGTRRI-GVDEHTPVVTASVFKVPIALELARQAA -EGGLDLGERITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLILDRV-GK -ESTEKSLRRLGFEQTTVPQDCGEVLGALRPEHTCATTGEEITRLLGLIWRDEAASPVACA -DVRRWMELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTEA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella amoyensis TaxID=996641 RepID=A0A561BXX0_9ACTN ---------------ARGAFGVWLGRLDGLPVF-QHRAETTHYSASTMKLPVAMAMMRRVA -AGELALDQPIQVHNDFASAEAPATWTRMGAKVPLGWLATEMITLSSNLATDLVLEQV-GV -DAANAVLAEYGSGASVIRRGIDDAAAQ-RAGISNLMSPADLAAVLVAVGNDKT---PGGE -YVRDLLAGNQW-NGEIPAGVPAGTRVEHKNGWDTT-IRHDGGIVYPPDAEPFVLTACTTS -ELPD-AEAQRLIAAIATEAWQH- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 54-19 TaxID=1895928 RepID=A0A1Q3T4A6_9CHLR ----------------DAGFGMVIHNLDTGEKF-EVNADQLFESASLYKIFVALTVYYDMA -GGRMSPNDQITLIPADAHDEDGYTIVSVGDSLPVSTLLEKMIVDSNNTAGLMLLFQV-RA -TRMKQIAADLGFTGSDFSDTYN-----------FQVTPTDLDLYFSRLADLKLMGAKYDQ -PLLDLLSRSLP-RDRIPAMLPEGTHVANKTGNLG-GVINDAGIIWLPNGNRLIVSVLTHH -VDED--AARQFIAELSLAAYNYy ->[subseq from] Beta-lactamase class A n=1 Tax=Frankia torreyi TaxID=1856 RepID=A0A0D8BAH1_9ACTN -------------TQAGGRRAVAVEALRGPAVRvEVNAHTPQPGASTLKLIVAAAVHDAAD -AGQIDLSERVNCRDLHPTIFPTVMAAFDDGDLALRQLCALMLITSDNAAADALLDRV-GH -DTVNATARRLGATATTLAVDFRDEQLG-AAGRRNTTTAGDLNLILRGLAGHER-----YR -PVLASMRNNLR-NTRIPARLPDRTPVAHKTGSLD-GVVCDAGIIYGQHTD--VAVAFLAD -GESDSARTSIAIADTVATIW--- ->[subseq from] Beta-lactamase class A n=2 Tax=Moorella thermoacetica TaxID=1525 RepID=A0A0S6UD24_MOOTH --tTLQQQIQNYLADKPGTYGIYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD -QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITTSDNIAYNMLRNFV-GK -GSIANYMQSLGGQTV------------FPG-GQNLSTARDMAIYVQAALNSAN-TSANGR -RLLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN -VP-DPDQGFANIATITRMIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Planktothrix sp. UBA8402 TaxID=2055759 RepID=A0A3C1P963_9CYAN ---DLKTAIMGLAKDSKLKPGVFLVDLDTGNYV-DIQGEEALPAASTIKVPILVSFFQAVD -EGRLRLDEVLTMAEKHIAKGSGELQDQPGSKFTALETVTLMIENSDNTATNMLIDRLGGI -ESLNQQFASWQLKQTQMQNILPDLEGT------NKTSAKDLVNLMAEINQGKLISLKS-- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Odoribacter sp. CAG:788 TaxID=1262909 RepID=R5PL24_9BACT ---TLQKQIRSILKDKKAMIGVAVLY-NGKITV-SVNNDQGYAMLSTFKFPLALAVCDYLD -RQKLPLETEIYVSKADLHPYSPLRDKQPEGDISIKELLRYCVSLSDNNACDILIRYIGGI -ERLQQYIADLGFPDMVIVATETQMHQQTGNQALNRTRPSAAVLLF--------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00035F5E68 -----------HLDRIPGTVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AERLAPDTAVPVRNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARRSSTGRGIEDFAAR-AAGITNLVTAADLAALLRDLALGALATPESCA -AMLDLLVAQEH-RVDLAAGLPAGTRIAHKNGWVR-GVRHSGGVVYPDDAPPYVLAVCHTD -EHSDDTDACQLLADVSAHAF--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. LRa12 TaxID=2563107 RepID=A0A4V3T8U7_9ACTN ------------------------------DEV-AVGADEPVVIASIFKVLLVLEFARQVT -AGQLDPRARVRVMAGDRLGGWGTAGCADDVELSLRDLALFAISVSDNSAADLLLAQV-GL -DTVRLLVKELRLERTRIVGGPRDVLQVLDPSRTNASTPREITRLLRLIWCDEAGPPQACA -WVRELMSRQVF-RHRLVSGFPDEVTVAAKTGTLP-GLHMEAGVVRYPDGSRYAVSVFART -RESSRTAVDAAIGTSARIAVD-- ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Moorella thermoacetica TaxID=1525 RepID=UPI0008FB1B71 --tTLQQQIQNYLADKPGTYGIYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD -QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITTSDNIAYNMLRNFV-GK -GSIASYMQSLGGQTV------------FPG-GQNLSTARDMATYVQAALDFARTSADGRR --LLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN -VP-DPDQGFANIATITRMIYDY- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium ulcerans TaxID=861 RepID=A0A2P1S168_9FUSO -----EERIKKIIEENSGVTGVIIRD-SSGKMI-TINEEVVFPSASIIKLFILMALNKD-- -----EYNKKIELKKEDKVGGCGILKVMGDGLLTVKDAAYLMICLSDNTATNILIDYI-GM -DKINECIKEKGFTGTVLGRKMMDAEAR-KAGKDNFTTPKDVLGVLEMLCENS-------- -DDLDMLRNQAY-NNKIPLYFAREVDFAHKTGELMY-IEHDTGRLFYDGG-WVDIIVLTKD -LE-KNEDGIKINSLIGKVIFDNy ->[subseq from] LysM peptidoglycan-binding domain-containing protein n=1 Tax=Moorella sp. Hama-1 TaxID=2138101 RepID=UPI000D64B5E1 ----LQQQIQNYLADKPGTYGVYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD -QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITTSDNIAYNMLRNFV-GK -GSIANYMQSLGGQTV------------FPG-GQNLSTARDMAIYVQAALNSAN-TSANGR -RLLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN -VP-DPDQGFANIATITRMIYDY- ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI0004891AB6 -------------DRMPGTVSAYLARLDAVPTW-TRRPDTTHYAASTMKVAVLVSLYRALA -AGRLAPDTAVPVRNEFDSAQPGAAWERIGGTAPLHWLAERMIVRSSNLATNLLLNQV-GL -PAVADVWARAGARHSVTGRGIEDFAAR-AVGITNLVTAADLAALLRSLALGALATPESCA -AMLDILVAQEH-REDLAAGLPAGTRIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCRTS -DRPDRSADEDACQLLADLSA--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacterium sp. XM4083 TaxID=2583238 RepID=A0A505HAA1_9MICO ------DEINGVWTSLGAQGFLYAEHLGTHRSL-GIRESARIPLASVGKVAVIAGLLDAAA -DGTVDLAQRLLVDPAHSTPGTGIAGLLDPVEMSVRDLAAMALSVSDNAAADTLFDLV-GP -DRIMAVLHRGGIRSFEVTSPMSHLYDLLPDSAFNTGTVRATAKLFELIHTGQLLGPEGSE -TLRRLLRKQIF-RHRIAAGFPDAVQYYGKTGTFLN-FRHEAGVVVDSDGSAYSIAVFTRS -SIATQPELDASIGYCARLAIEH- ->[subseq from] serine hydrolase n=1 Tax=Nocardioides albertanoniae TaxID=1175486 RepID=UPI00114DCA61 -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPTPVHPDD--QQDPETWAAVGSSLPLGDLVRRSLIVSGNLAANLVLERV-GL -DQVADVLEEAEVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKVLTKLASGRLLSPESTA -ELTGALVDQHY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIHPSEGDPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces qinzhouensis TaxID=2599401 RepID=A0A5B8JKL1_9ACTN ---------ARSAAALPLSLSVAAIDVDDGRST-GVDDTAVLPVASAAKLLLLAEVARGLD -AGELDPGRTVAVTDDDVVHGTGLLVRLSRRDWTVEDLCWLTASVSDNTATNALLRLV-GP -ETTARLARSLSLEALTLHDRVRDVRGPGDPPVFATGTARALAELVAHAARGSLVSPGASR -RLLGWMRSNTDYAACFPEPLPGGLLLANKTGTDP-GVRADAGVFIGARRVAYAVVAHWDT -ALGDSTERARAVRDVGRTLAE-- ->[subseq from] Uncharacterized protein n=2 Tax=Bacteria TaxID=2 RepID=K2C4D5_9BACT ------------------NYSLYVKDYNSDFEL-GINEEVIYTAASVNKIPILSALYYYTQ -AGEIDLDESITLQEADIQDGTGVLRYTPGATYTIKTLARLMIQKSDNTAAYILLNNIVRI -ERTQKLMESWGLIQTDIAN--------------NKTSNKDISMLFEKIISGDVANQAYTQ -EMLSFLKDTDF-EDRLPAMLPKSVTVYHKIGTGVR-IIHDVGYVTDGNL-NYYVGIFTSD -VP-SEDDAVLLMAKLSKSIYN-- ->[subseq from] Serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A4R5YHN4_KOCRO ------------------------------------------------------------- -----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHEQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] serine hydrolase n=1 Tax=Streptococcus urinalis TaxID=149016 RepID=UPI000F8332EF ---------------------------DGVEYA-ASRETVSQRSASTIKLFILTSAYEKAQ -RGELNMSSNYTVKSSDIVVASTALANSAGQTYSLDTIARFMVQYSDNTATNIMISAIGGV -SAVNAEIRRMGYTQTTLNRYMR-IQSQIDAGLENYINVHEAVDLLKNIYNNTLQNTTAEP -TMLADLSNNYY-KLWLPASIQSQAQTWDKPGNDGFGVENDIAAIKVNGK-TYIVGVLTQH -TGSNGVSNTGVFANFGKSIV--- ->[subseq from] serine hydrolase n=1 Tax=Frankia sp. CpI1-P TaxID=1502734 RepID=UPI000707ED6C -------------TQAGGRRAVAVEALXGPAVRvEVNAHTPQPGASTLKLIVAAAVHDAAD -AGQIDLSERVNCRDLHPTIFPTVMAAFDDGDLALRQLCALMLITSDNAAADALLDRV-GH -DTVNATARRLGATATTLAVDFRDEQLG-AAGRRNTTTAGDLNLILRGLAGHER-----YR -PVLASMRNNLR-NTRIPARLPDRTPVAHKTGSLD-GVVCDAGIIYGQHTD--VAVAFLXD -GESDSARTSIAIADTVATIW--- ->[subseq from] serine hydrolase n=1 Tax=Catellatospora sp. H14505 TaxID=1969805 RepID=UPI0011820BC7 -----TNRVADVFAGADMQGWLHARDLDTGREV-AVGAHDQVVIGSIFKILLVLEFARQAA -AGSLDPADRVLVRATDRLGGWGTAGCADDVEASLRDLAYFTMSVSDNTAADLLLCRI-GP -DLLPLLAQELGLTRTRLIGGPREILAVFDPAHTNSSTPEEVTRLLGLIWQDEAGPAQACA -TVRALMFRQLF-WTRLAAAFPPGVRVAGKTGTLP-GLHMEAGVAEYPDGGRYAVAVFAKT -ERLSMPELDLVLGRAAKLAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix carnea TaxID=1280637 RepID=A0A2P8II60_9PSEU ------ARVRAAFTDAGVTGRLHAVDLDQDREV-SVGADDPVVLASVFKVPLVVSLHHSTH -----DLTRRITLGQDRSTGPTGVGGMLDPVTMSLRDLAYLAITVSDNAAADALMDLV-GT -DDVNRTLRDLHLTRTVVVHRARDFMRALNPDHTNRGTARDLTTVLRHIWQHD-----DCA -PIRHTMARQVW-PHRLASGFPDDVRVAGKTGTLPT-IRNEVGVVEYPDGGRYAVAVFTRS -ASFTLPQADAVIGTAARLAVEH- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Candidatus Woesebacteria bacterium TaxID=2026804 RepID=A0A420Z6M5_9BACT -------SFKEKTKNLSGVYGFYVIRLNSGVSY-GVNERDIFEPASLNKLPVILAMYIKAE -KGDIDLETTYTLKDSDKVAGSGSLYGKPEGYLTYRELLKYMGKESDNTAANIARSIL-GE -EDIRQAISTIGMDNTVVIGE------------DQETTPYDIGLFFEKLWEGDIVSKKHRD -EILEYLTDTIY-EEWLAAGIPSDTDVAHKYGREVH-VVNDAGIIFTD--EPFILVLLSKG -IV--EREADQVFPELSRVIYR-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pisi TaxID=589240 RepID=A0A495JFA6_9ACTN -------RLDAELADTAGTVSVYAGRLDAAPAY-TRLPDRTHYAASTMKVAVLGALYRAAD -TGTLDLDAPVPIENEDSAQDAPRFWARVGGHAPLRWLAHRMIVRSSNLATNLLLGHV-GL -PAVNAVWDLAGARHSHTGRGIEDFAA-RDAGIDNPVTAADLATLLGTIARGALATPATCA -AMLDVLLAQEH-REDLAAGLPAGTRVALKNGWVR-GVRHAAGVVFPDDAPPYALAVCTSH -HPEPDQTARRLIARVSATVWA-- ->[subseq from] Uncharacterized protein n=3 Tax=Fusobacterium TaxID=848 RepID=C6JN74_FUSVA -----EKRIREIINENSGVTGVIVRD-SFGKKI-MINEEVIFPSASIIKLFILMALNKD-- -----EYNKKIELKKEDKVGGCGILKVMEDGLLTIKDVAYLMICLSDNTATNILIDYI-GM -DKINESIKANGFRGTVLGRKMMDTEAR-KAGKDNFTTPEDVLKVLEILCGN------SD- --DLDMLRNQAY-NNKIPLYYPREVDFAHKTGELMY-TEHDAGRLFFDNGW-VDIVVLTKD -LE-ENEDGIKINSLIGKLIFDNy ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides albertanoniae TaxID=1175486 RepID=A0A543ACE5_9ACTN -----------------------------------QNVNQQHYAASLMKVPVAIAAYRLRD -RGLLSLDEPTPVHPDD--QQDPETWAAVGSSLPLGDLVRRSLIVSGNLAANLVLERV-GL -DQVADVLEEAEVTMTTVSRGIEDAPA-REAGLQNLVTANDMGKVLTKLASGRLLSPESTA -ELTGALVDQHY-RDAIPLGVPEDAVVGNKTGWVD-GVRHDMAIIHPSEGDPQVMVVLTTG -LDD--DESEFRISEVARYLWS-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Sutterella parvirubra YIT 11816 TaxID=762967 RepID=H3KI40_9BURK ------------------------------------------------------------- -------------------PHAPVLSKMNPDDISVKDAARAACSESDNRAANLLMKTLGSP -AAMTAWLQWKGDLRTRIDRYEPDCNKTSAYDVRDKTRPSAITQLWRKLYLD--FTPDERM -EWEDMLKANKHSAHLFKAQVPQGWTVADRTGSGSETNSSVHAMLFNPEGAAWFAAVHVRM -PATDLQTRDAVLAKACGIVM--- ->[subseq from] Beta-lactamase n=1 Tax=Saccharothrix sp. NRRL B-16348 TaxID=1415542 RepID=A0A0M8Y1M9_9PSEU -----------------------AVDLDHDREL-SVGADEPVVLASVFKVPLLVALHHSAH -----DLTRRITLDADRSTGPTGVGGMLDPVTMSLRDLAYLAVTVSDNAAADALADLI-GL -DAVNDTLRELGLTRTLVVHRARDFMRALDPDHTNRGTARDLTTLLRHVWRHDDC-----A -PIRRAMALQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVEYPDGGRYAVAVFTRS -ASFTLPAADAVIGTAARLALEH- ->[subseq from] Beta-lactamase class A n=1 Tax=Aminicella lysinilytica TaxID=433323 RepID=A0A4R6Q610_9FIRM --eELEEYLRDRTGSLAGHVGIYCQELATGKTM-DVAEEDVFESASVIKIWIMAAAYDLMA -KGKLSPDEILTLKDIDKVPD---EAMHPGLELTVEDTIRLMILISDNTATNMMIDLV-GL -DVVNNFLNKMGMSKSRLCRRLFDSDPS-GMGQENSISLSETGWFFRQLYDGTLVSAEASE -KMSSMMQNQQT-TYKIPFFLR-EIPIAHKTGEDC-GIANDVGIVFAKN--PFIFCFASNG -VD--VAAADRLCQDAALEVYNYy ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536JSW7_9CHLR ---ELVRQLDGLIGSFPGGAGIWVADPNIATPLyAHDPEEQVIAASLYKLGVLAEAERRVD -TGELHYNDIITIEPEDITADGSF--EDAGTQLTLDQALEVMITVSDNGTALALWHIL-GG -ANIDSTLQKAGVNNFHVA---------FDDTEDNWATPHAIGTFFTLLAKRQLISAGASD -RMLSRLERQQI-NDRLPAQLPPGVVIAHKTGNLG-GVMHDAGIVYTKTGPRVVVAMTWDA -PDE---DALNFISSLGSLVY--- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis alba DSM 44262 TaxID=1125972 RepID=A0A229R8F3_9PSEU -----IETINARAKETGVRVRLHAAEIDGTRRI-GIDETTPVVTASVFKLPVALELARQAA -DGGLDLGEPVTVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLIVARV-GK -AETEKTLRRLGFEHTTVPQDCGEVLGALQPEHTCATTAEEITRLLALIWRDEAASPTACA -DVRRWLELQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=UPI000DF69A2A --------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD -DGRLDPRARVLVDPATATPPTGIATLSDPVAMSVRDLLRSMVAVSDNAAAGVLMRLV-GL -EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA -FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Nocardioides sp. SB3-45 TaxID=2558918 RepID=UPI0012474F24 ----------------SGTVSVVLRVSGEEARL-AIDPEAQHYAASTMKLPVLVAALRRAE -RGELDLDRRVVVHDDSVVPGQRFTWAALGDAVALRDLVGRMVTVSGNLATDLVLEQV-GP -AEVATVLDLAGCSGTTLPRGIEDYPA-RDARLDNLVTADDLARVMVALAEGRLAGPAATA -ECERVLRAQTY-RGGIPAGLPPRLVIGNKTGWID-GVNHDVALVRAAGLPPVGLAVLVSA -PG-TPEEREAGIARVAAAAWD-- ->[subseq from] Serine hydrolase n=1 Tax=Acidobacteria bacterium AB60 TaxID=1230846 RepID=A0A5M8S8P4_9BACT --rELEQQLQAIAAALHGKVALYAENLKTGQSA-GLAADEPVKTASTIKMAILLDAAEQIR -AGHASFGEKLVLSHENQVEGSGVLGELDTPLLTLRDTLTLMVVLSDNTATNMAIDRL-GL -ARINDTLKAAGLKQSYLYKKVYVPATDQPRFGLGKTTAREMAQIMARLAQGSAAGPGDCA -TILHMLRNQQ-DRDGIPRYLEHGSAIANKTGALD-ALRADVALIASKAG-PVVIAAYTYD -NANGDNEGQQTLGKLAKAVLERw ->[subseq from] Serine hydrolase n=1 Tax=Bacillus sp. KQ-3 TaxID=2483800 RepID=A0A3M7TQY8_9BACI ---TLGHTVQTLSKKVKGDISLHIHT-E-EGEI-GYGSATPLIAASLIKVPCVYAAVLKSK -EGTFELDEETIVSAEQKIGGTGVLFHMPGEVITNRQLLSLMITVSDNTATNVIIDRI-GI -PYIQKTMVSAGCDSSWIKRKIIHTDPN-TQPLNNIMSARDFNRILMAINQGKNLTEENRE -FILSSLTGQQINHKLFSDGLPPTVRVAHKTGDDI-GMEHNGGMICLNGKTAYV-TVMTVK -LE-TNIEGQEYIRKVGKAVYNY- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=candidate division WWE3 bacterium GW2011_GWB1_42_6 TaxID=1619115 RepID=A0A0G1DTY5_9BACT -----EIQFAELTKKLPGVYGLYIKDVGSGREF-KYNDTTEFYAASLYKVPIGAAVLKEVE -AGKLNLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY -KNVQETFNEI-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGGYLNDADKK -YLADLMVNTSF-EDRISAYLKEGLIFSHKIGSWPD-SWHDCGVVYTETKSELIVCLMSQR -A---------------------- ->[subseq from] serine hydrolase n=1 Tax=Brachybacterium sp. EE-P12 TaxID=2306299 RepID=UPI000F0750B5 -----------------VRLAHCLLD-ADGTVLsAAHAEEPFYAASTIKLHVLLAVLRAAE -AGRVDLAAELPVTRTFTGAGQPFTPTHPAPGVAVRELAVRMIDRSSNEATDQLLELV-GL -DAVADVVRELGLTATRVERRIGDAA-ALSQGLTNETSAADLARTMHALVTGARLSEPSRE -LALAALAAQRI--PIIATALRDGVPWGSKSGWVD-GYRHDVAHVGAPGSDSRVLAVLTAG -LDAE-AADARIIAL--------- ->[subseq from] serine hydrolase n=1 Tax=Staphylococcus pseudintermedius TaxID=283734 RepID=UPI000C1B86A7 ------------------------------------------------------------- ------------------------------------------------------------- ----NERLKELGDKVTNPVRYEIELNYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKENKK -FLLDLMLNNKSGDTLIKDGVPKDYKVADKSGQATYASRNDVAFVYPKGQEPIVLVIFTNK -DNKSDKPNDKLISETAKSVMKEf ->[subseq from] serine hydrolase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=UPI001143E1F0 ---RLTREVSDELEAAGLRARIVVRDLDSQAEI-SIAHDGPVPLASVVKVPIALAILNRIA -DGRLEADRQVHVAPGRFEGGSPMGTSRFRHPIAVDDLLMLSVCFSDNTATDALLDLV-PT -EEVQRDLDDLGLGGIQIRHHLDALVRQLDVSQANVATAAGLTDLLAELWRPERIQTSAAS -RLRELMAGNVVRHRLAPDLMSDAAKWSSKTGTLLH-LRHEIGVVEHSDGQTIAVVVLSES -SNAVQPAAEAALGAAARALH--- ->[subseq from] serine hydrolase n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=UPI00079A9055 --------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD -DGRLDPRARVLVDPATATPPTGIATLSDPVVMSVRDLLRSMVAVSDNAAAGVLMRLV-GL -EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA -FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] serine hydrolase n=1 Tax=Bacillus aciditolerans (strain JCM 32973 / CCTCC AB 2017280 / YN-1) TaxID=72581 RepID=UPI000EB0EF5F --qELRKYLGELQNVTQCKFHIYFKVISSEIEF-QWNASDVIPSASTIKLPILLASLQRYY --GDPSIKTKLFSIKDNWDSGTGVLRYLSKDNLPLMDLNTLMIIISDNVASNTIIDYL-GF -DVINETVQRFKLSKTKLFRKFDEINK-HAEAADNMTTAKEMGLLLEKIYLNSLNRDKICK -KAIEILKHQQV-KDRIPRYLPESVTALCKSGDYPD-GYHDIGIIEPANFYPYVLSAFSTN -CK-SKDIAVENIANISQFIYQQ- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFOXYB1_FULL_47_11 TaxID=1798401 RepID=A0A1F6BDF6_9BACT ----LKDVVDGALEGATGSYGIYIKNLKTGESY-VSGEHNVFDSASLYKLWVMAVVYQKIQ -DEQFTEDQVLREDVFVLNQIDPELAEKTEGVFSVREALRQMITVSDNYAALLLTEKI-GL -SSVATFLKENDLTESAVGTTG----------GPPTSTPYDIERFLEKLYREDVANPKYTA -EMIDLLKNQKL-NNGIPKYLPDASSVANKTGEIDR-FKHDAGIIYTDNGD-YSIVVMSES -AYP--PGAQERIARVSKAVFDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=A0A1H5BWR7_TSUTY --------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD -DGRLDPRARVLVDPATATPPTGIATLSDPVAMSVRDLLRSMVAVSDNAAAGVLMRLV-GL -EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA -FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535TKB8_9CHLR ---RLSADLALIAGTSGGRVGISLQELSGPRSL-SVNGGQSFVAASTYKLPLLMAEAQQIA -SGQARPSDLLCYAPGDAEDG-WFMDYQPGSCFTRDQLALRTGRYSDNTAAHILVRYLGGA -DALNRYAKSMGMTNSAL--WT-----------PNTTTPDDLSQALVSEALGRLGGAAAQA -WLYPILTHTAT-ERAIPAGLPAGVTVAHKTGSMP-GAENDAAYVRNG-RIAYVLSITVDG -LD--EGTAWSLMARISARVWQY- ->[subseq from] Serine hydrolase n=1 Tax=Kribbella antibiotica TaxID=190195 RepID=A0A4R4YJY9_9ACTN ----------------SGEFGVWLGRPDGTPVF-EHNAERTHYSASTMKLPVAMAMLRKVA -AGELSLDQPIAVHNDFASQEAPETWTKLGTKVPLGWLATEMITLSSNLATNLVLEQV-GI -DAAQAVLAEYGDGASAIRRGIDDRAA-QAAGISNEMSPAGLAGVLVAV---------DNQ -YLRDLLAGNQW-NGELPALLPPGTRVEHKNGWDRR-IRHDGGIVRPPDADPFVLVVCTTS -ELPD-ARAQQLIAEIALEAWN-- ->[subseq from] Uncharacterized protein n=1 Tax=bioreactor metagenome TaxID=1076179 RepID=A0A644Z322_9ZZZZ ---------------LDGTVSYYYRAFDKGEAA-CCNMDAPHDAASIIKLPIMVEAIRQFE -SGEAARDEVIRIRDADRVPPCGVLTFHEGLPVQLIDLVWLMVTLSDNMAANLLMDRL-TL -PAIRREMMALGMTGCRLNRKLFA------PGPGNIITCRDICMLFEQLYAGTLVSAAASH -EMLDMLTGQQL-QNKIPMLLPLDMRIAHKTGEDE-GTSHDVGIVYAK--KPFLVGFFGTG -VD--APSFNRT------------ ->[subseq from] serine hydrolase n=1 Tax=Fodinicola sp. GKU 173 TaxID=2681555 RepID=UPI0013D4F5B1 -----DEELTELFLAANCTGTVSAVALDGSGEA-GFGADEPMVAGSVIKICVALEAERQFA -DGRLDPARRVRLTAADRTPGTVGFSLFQDDIVSLRDLVAPMLTISDNVATDALVRAA-GL -DSINASLRKLGLTETVMTGDIRTVIDELRPATATRTTAREMTTLLRLIWTDQAGPAAACR -RVRELMAKQLT-KNRLASGFPYPATVSAKSGGLAGTVRNEAGVVEFPDGRTYAVAVFTRT -ERDGETPMNHAIGQAAALAV--- ->[subseq from] PEGA domain-containing protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536KQM2_9CHLR --------LNAYLGGLGGRYGVWLDDLSSGRQI-GYHAGDSMEAASVIKLPLALYLLDQAA -QNKLKLSDTIQLEDSDFMGGTGTLYYAPGDTLSYQDLLGLLIQQSDNTAWKALKRVL-GS -DKVDAYAASIGAPDC---------HQ-----EDDNCTPQEAGLMLAKLATSAVLDAGGRQ -MLIGLLENTAF-NDRINYYLG-NVAIAHKVGMDG-GVMNDAGIVLGSHQ--FVISMFTDS -DNPD--QGVQAIRDVSRAAAKYy ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_12_FULL_46_16 TaxID=1802513 RepID=A0A1F8B053_9BACT --kKAKEKFKEVTKDLSGLYSFLIIDLEKDISY-GTAETNTMQAASLIKLPTLAALYLEAE -KGNIDLEAKYTLKQSDKLPGAGSLSGKPAGTLTYRDLARLMGKQSDNTAFGIVRRLL-GD -EKINQVTAEIGMTKTSLA--------------ENTTTPQDIGLFFKKLWKKEIVSDDSRD -EILGFITDTIY-ENWIVAGVPDDIRVAHKYGRELH-VVNDAGIVFSK--YPFVLVVMSDG -VV--EREADEVIPKIAERL---- ->[subseq from] serine hydrolase n=1 Tax=Haladaptatus cibarius TaxID=453847 RepID=UPI000678709E ----------CYADRIDGELGVFLYGPDEFDTVyTRNARRAFRSASVVKILILYALYERYD -GRLDSLAESCPLAPENRVGGSGILH-LLDATPTIEELARAMIATSDNAATNQLIDHL-SM -TTINDSAAKLGMKHTRLARKMMTTLEVPEDEPANVTSPVDCARFFADIGCEATLSANAYE -RLCVPLSAQKD-TSMVPRYLPYETEIMHKTGWLPT-AALDAGLLSVPDEPPLVFSVFVDS -VSHG-ADAADAIAEIGDAVF--- ->[subseq from] Serine hydrolase n=1 Tax=Peptococcaceae bacterium TaxID=2052179 RepID=A0A3B9M2Y0_9FIRM --rALEQQINNYLASQPGVYGVYFEDLYTGRSF-GIKADDAFPAASTVKFPTVLFINKLVS -QGILDWQQKLTYNAAQHYQGSGILQFGIKDGLTLRSLTTQAITTSDNIAYNMLRDFV-GK -GSVANFMKEIGGTTVYP------------N-GNNWITPRDMGTYLKV-ALNWSQTDSNTA -RLLDDMANGIY-NEGIPLYLPDMVKVAHKEGFIW-GCPSDVGIVYG--KRPFIIVVYAYN -VE-DPDQGFANIATISRMIYDY- ->[subseq from] Cell wall-binding protein YocH n=2 Tax=Moorella thermoacetica TaxID=1525 RepID=A0A5B7YPR5_MOOTH --tSLQQQIQNYLADKPGTYGIYFKDLASGQSF-GINADTPLPAASTVKLPAVLFINSLVD -QGVLDWQQKLTYNSADYQGGSGILQFSVKDGFTLRTLTTLAITASDNIAYNMLRNFV-GK -GSIANYMQSLGGQTV------------FPG-GQNLSTARDMAIYVQAALNSAN-TSANGR -RLLDDMANGIY-NEGIPLKIPAGVTVAHKEGFVW-GSPGDVGVVFG--SRPFIITVLSQN -VP-DPDQGFANIATITRMIYDY- ->[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048E9997 ------------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-REDLAVGLPAGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG -DDPDHSPDEDACQLIADISAR-- ->[subseq from] serine hydrolase n=1 Tax=Kribbella sp. YM55 TaxID=1572660 RepID=UPI0010397248 -----KARIRGIFEDAGVRGWLHAVSLDDGASV-ELDADVVVPLASVYKLPLLAGFSRLVD -LGELDPREQVTLEPSSRTAGPTGLSMFADPVVSLRDLALSMATVSDNAAADALLDIV-GL -RRLAAILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRQLWAGELLSAEQTE -FVKATMHRQIF-LQRVASGFPDGVRIAGKTGTFG-ALRHEAAVVTLPDGAAFAIAILTLA -ARGDQPRVEAAIGEAARVAVD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces TaxID=1883 RepID=UPI0004C98F01 ----VAEAIAADWAAVGVRGSFLARNLDTGEQL-GFDADEPVPLASVAKVPLALVVLDRVA -AGELDPARPVTVDPRTSSVPTGLAAFRHPATVAVGDLLLLMLSVSDNAAADALFDLV-PT -AETDARLRAWGCDGIRVRHRMNHLYETLDPAHANAGTAAALVGLLQRVWRDEISTPSATA -ELRRLMGHQVF-TQRLAGELRADLRWSGKTGTFLH-LRHEIGVVEADSGDRVAMAALTRA -TRRAAPDIDQAIGAAGRDAF--- ->[subseq from] serine hydrolase n=1 Tax=Kocuria sediminis TaxID=1038857 RepID=UPI0012E12FEF ------------------------------------------------------------- ------------------------TDTVPGTTFTVREAVERMITWSDNVSGAALGRWL-GW -HEVQVFAQGQGFESTTYDPDTGEARTV-----AMTTTPDDVADLLDRLRGGELLSGPSTT -LLLGFLAAQQL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG -WSG-------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Terriglobus roseus (strain DSM 18391 / NRRL B-41598 / KBS 63) TaxID=926566 RepID=I3ZHL4_TERRK ----PDEAVKQVIAQHHGSVALYAHQLNTGKTI-SIDADKPVQTASTIKLALLWTAVHEIA -LGHATWDEKVTLKPGEGVAGSGILHFFDTPILTLKDIATMMVIVSDNTATNLMIDRF-PT -KQVDGNMTALGYTDTWLYKKVFKPADDQPKFGLGKTTPHQIAQLIEKIGRCDAKADTACN -VAIDMLRNQF-YRDTIPRYLEKGSGIASKTGSLD-ATRSDVAILAAKSG-PIVLAVYTYD -NADKDNEGEVAIAKIAQAVVKAw ->[subseq from] serine hydrolase n=1 Tax=Salinispora pacifica TaxID=351187 RepID=UPI00037650C4 -----------HLDRIPGTVSAYLARLDAAPTW-TRHPDTTHYAASTMKVAVLVALYRALE -AERLAPDTAVPVHNEFDSAQPGAAWDRLGGTASLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARRSSTGRGIEDFAAR-AAGITNLVTAADLAALLRDLALGALATPESCA -AMLDLLVAQEH-RVDLAAGLPAGTRIAHKNGWVR-GVRHSGGVVYPDDAPPYVLAVCHTD -EHSDDTDACQLLADVSAHAF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Brachybacterium sp. AG952 TaxID=2183989 RepID=A0A4R6QX67_9MICO ---------------TEVRLAHCLLD-ADGAVLsASRADDPFYAASTIKLHVLLAVLRAAE -QGELDLDAELPATCTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL -DAVAAVVGELGLGATRVERLIGDAS-ALERGLTNETSAADLARTMHHLVAGPGLSDDSHE -LALAALHAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAYVEDPAGGRRILAVMTAG -LAED-EADARITALAA------- ->[subseq from] Uncharacterized protein n=3 Tax=Firmicutes TaxID=1239 RepID=A0A3C0LY65_9FIRM ------------------------------------------------------------- ---------------------------------TTKHLLDEMITVSDNSATNELVRYLNGM -KKVNAFIKAQGFEYTHEYNGLEDTSLWYDADTKNTTSAKDCGRLLERIYRGEFISHLASR -QMEELLLNQQV-TYKIPSTIPSESRVANKTGETSD-CENDAAIVYTPKGD-YILCIMSCE -VS-SKSSAVDSLQEMSSLIYSYf ->[subseq from] Beta-lactamase class A n=1 Tax=Tamaricihabitans halophyticus TaxID=1262583 RepID=A0A4R2QXM4_9PSEU -------EIIARAEEVGVSVWMHARAIDGTASL-GIDATTPVVLASVFKVPLAVELANQAE -RGRCDLAEQVTVPAGPKVAYGLATFQHPA-TLSLDALATLMIGISDNVATDVVFARI-GK -RAVRELCDRLGLADTAIEQDCAELLGALRPEQTCRSTALDMTALLSMIWRDEAAGPAACA -NVRRWLGLQVW-PHRLRSGFHDEVRISGKTGTLPT-IRNEVGVVEYANGERFAVAVFTEA -IDAQAPERDGFIGFAAARAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Phycisphaeraceae bacterium TaxID=2026777 RepID=A0A2D5Z900_9BACT ------DALDRLARAFPGRVGIYIEEVAGGARY-AFAADERFPTASVFKIPVLLTLYQLAE -AGRLSLDDRHRVAADISTHGTGILKQFTDAPLSLRDHCRIMISHSDNIATDTIIRAV-GL -DQINAMLERQGLANTRVPMEIGRWHYAFSDRLENVASPRDLAALVGRIDQGKLAGAAATE -SMRQMLR---LGDGPITSVLQPNAQTMSKRGSSRR-IVCDVALVPLAAG-PLVISVMTLE -DQ-PRKSGTALIGEVTRLAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria polaris TaxID=136273 RepID=A0A0A6VV09_9MICC ----LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -GQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA -LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. CNJ-770 TaxID=1904964 RepID=A0A1Q9SNK1_9MICC ------------------------------------------------------------- ------------------------TDTVPGTTFTVREAVERMITWSDNVSGAALGRWL-GW -HEVQAFAQWQGFESTTYDPDTGEAG-----TVAMTTTPDDVADFLDRLRTGELLSEPSTT -LLLGFLAAQQL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGR-EYVVAVLTDG -WSG-------------------- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Candidatus Omnitrophica bacterium CG11_big_fil_rev_8_21_14_0_20_43_6 TaxID=1974747 RepID=A0A2H0LNZ8_9BACT ------------------------------------------------------------- ---------------------------RAG-VFTVEELIGLMIYDSDNTATNILTNLV-GI -DYLNLVFIRLGLKDTNLSRKIADFKTR-DRGVENYTTAQDIAGLLEQIYRRKLISRDLSD -KCLRILKLQRV-NDRIPKYLPADVMVAHKTGLERN-VCHDAGIIFDQEGD-LLICVLTKH -NNPNAQASKNFIARVALHTYR-- ->[subseq from] Serine hydrolase n=1 Tax=Tsukamurella asaccharolytica TaxID=2592067 RepID=A0A5C5RC41_9ACTN ------------------------------ATL-SVGGEQPVVPASVYKVVLLVAAGRAVD -EGRLDPRARVLVDPAAATPPTGIATLSDPVEMSVRDLLRSMIAVSDNAAAGELMRMV-GL -DAVQKVVHDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAAQCA -FARAALAGQVF-RHRIASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEHPVAVAVFTHA -ARNDLPRVDAAIGTVAALAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. HM5-17 TaxID=2487710 RepID=A0A3N2P8Z1_9ACTN -------------AATPGTVSVYVGRPGIRPAY-TRLPESPHYAASTMKVAVLAALYRAAE -AGTIDLDAPVPVVNDFPSAGGGRFWARLGGTATLRWLAERMIIRSSNLATNLVLGHV-GL -PTVAAVWADSGARHSRTARGIEDFAA-RDAGLDNQVTAADLAGLFCAITRSRLAQPGTCS -AMLDVLFRQER-GEDLAAGLPAGVRIAHKNGWVR-GVRHGAGMVFPDDAPPYAIVVCTSA -AAGDDEAACRLIARISAMAWE-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NEAU-HG-1 TaxID=2697657 RepID=UPI001379006E ------------------------------REV-AVRADEQVVIASVFKILLVLEFARQAS -VGQLDPTERVLVRAADRLGGWGVAGCADDAEVSLRDLAYFAMSVSDNTAADLLLRRV-GR -DVLPMLAAELGLPRTRIVGGPRELVEVLDPAHTTSSTAREMTRLLGLIWRDEAGPAPACA -AVRELMDRQLF-WTRLASGFPPGVRVRAKTGTLP-GLHLEAGVAEYPDGRRYAMAVFART -ERTRRIDVDLAMGEAARIAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Lachnospiraceae bacterium TaxID=1898203 RepID=A0A3D4RBK0_9FIRM ------------------------------------------------------------- ---------------------------------TTKHLLDEMITVSDNSATNELVRYLNGM -KKVNAFIKAQGFEYTHEYNGLEDTSLWYDTDTKNTTSAKDCGRLLERIYRGEFVSHLASR -QMEELLLNQQV-TYKIPSTIPSESRVANKTGETSD-CENDAAIVYTPKGD-YILCIMSCE -VS-SKSSAVDSLQEMSSLIYSYf ->[subseq from] Serine hydrolase n=1 Tax=Brachybacterium sp. HMSC06H03 TaxID=1581127 RepID=A0A1F1XJX3_9MICO ---------------TEVRLAHCLLD-ADGAVLsSERAEESFYAASTIKLHVLLAVLRAAE -QGELDLDTELPATRTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL -DAVAAVVGELGLTATRVERLIGDAA-ALERGLTNETSAADLARTMHHLVAGPRLSGDSHE -LALAAMHAQTI--PIIGSVLRDGVRWGSKSGWVD-GYRHDVAYVEDPVGGLRVLAVMTAG -LAE--EEADARIAAL-------- ->[subseq from] Serine hydrolase n=1 Tax=Arthrobacter sp. MYb23 TaxID=1848603 RepID=A0A2S9DAD8_9MICC ---DITDQIRAIFAEADVTGSLHARAIAPGAGEiSVGADEPVVLASVFKIPVVLAFARAVQ -EGRVDPLERVLVGPKYRVGGIGAGGCRQDVEMSLGDLALFMLTLSDNAATDLILERV-GV -DAISTLLDELELLETHIGGGCLALWDLDPRKSLHRSTPREITTLLSSIWAGHP--DTPAN -QMIRSMMAEQVWTHRLSSGFDDSAIVAGKTGTLPT-VRNEAGVVTLPDGSSYAVAVFLRS -QSDRQPRADAAIGHAAYLAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria turfanensis TaxID=388357 RepID=A0A512IGS1_9MICC ------------------------------------------------------------- ------------------------TDTVPGTAFTVREAVERMVTWSDNVSGAALGRWL-GW -HEVQAFAQGQGFESTTYDPDTGEAG-----TVAMTTTPNDVADLLDRLRGGELLSGPSTT -LLLGFLAAQEL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG -WSG-------------------- ->[subseq from] Serine hydrolase (Fragment) n=2 Tax=Kocuria rosea TaxID=1275 RepID=A0A4S3PQU8_KOCRO ----LAADLEELAAEVPGELGVVLLGPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA -LLMGFLEEQHF-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Caulobacter TaxID=2648921 RepID=A0A0Q6U0P8_9CAUL ---RLQGRIEAIAARAPATLGVAVEDLTTRQLW-TFNGDQAFPLGPAARVPILAAMMAEAA -AGRLPPGELVTVRDVDLSPPSAVADAWPGRQWSVADLETLAL-HGDTTALDLLTKRIGGP -GAVNGWLDVQRIEGVSVDRYRRQIATARQGDARDTATPVAMARLLEAFAFRELGLAPDFD -GLLGH------DAGYLALALPKGARLAQAAGSARTPGSQALAVVELKDGRRIAFVIFLTG -SAADAAKREALITDVGRAVLEEf ->[subseq from] Serine hydrolase n=2 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536BEF5_9CHLR --dQLRSDLEAIARASGGRVGISLEELSGPRNL-SINGEQSFGAASTYKLVLLMAEAQQIA -SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP -DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG -WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG -LD--EGTAWSLVARVSARIWQY- ->[subseq from] serine hydrolase n=1 Tax=Tsukamurella tyrosinosolvens TaxID=57704 RepID=UPI000C7EDF81 --------------------------------L-SVGGEQPVVPASVYKVVLLVAAARAVD -GGRLDPRARVLVDPATATPPTGIATLSDPVAMSVRDLLRSMVAVSDNAAAGVLMRLV-GL -EAVQATARDLGLRGTRIVGGDAEIHAAYDPTFGSATTAADMTALLAAVWSDAAASAEQCA -FARSALAGQVF-RHRVASGFGSAPSIAGKTGTLG-ALRNEVAVVAYPGEYPVAVAVFTHA -ARNDLPRVDAAIGTVAAIAVD-- ->[subseq from] Uncharacterized protein n=1 Tax=bacterium UBP9_UBA11836 TaxID=2060920 RepID=A0A355TUT6_9BACT -----------------------------------ENLDKQFRAASTIKIPIVAALFYEAM -HKRLNLADLVAISEADIVEGGILCEVGVGRHFSWRELARLAIVISDNSASNLIIKKL-GF -TFINSFIKDLQAHHTVLNRYFMASPQ---EMGENYTTARDLALIMASLWQGRILDKSYND -EFWAILSRQQF-IEKLPSRILGQVKSYNKTGELDDGARHDAAVFTYKSHA-WGLVALTDQ -QKLPAWQIDWAMGAWSELI---- ->[subseq from] serine hydrolase n=1 Tax=Sciscionella sp. SE31 TaxID=1445613 RepID=UPI0004DF50F1 -----AESVATAWQRIGTSGSFLARELHTGREL-GFDVDTALPLASVVKVPIALVALDRIA -EGTLDPAQPVTIDPADKSVPTGVSAFRYPATLAIADLVHQMLTVSDNASADTVLDLL-GL -DAVEERLREWDCAGITVRHRMNRMYEPLDPAHANLGSAAALVDLLERVWLDRIARPEATA -ELRRIMGAQVF-TQRLSADLRDSVRVSGKTGTYLH-LRHEIGVVETDSGDRIAIAALTRT -DRRAAPDVDLAIGAAARAAFE-- ->[subseq from] Beta-lactamase (Fragment) n=1 Tax=Comamonadaceae bacterium TaxID=1871071 RepID=A0A4Q5VRV6_9BURK --dALRQEVERIDRASPGTLGVYVKRLDDGTTL-DYGGDRKWYLGSTVKVAVAITVLQQVD -AGQMKLGDTLVLQETDRIEAGPLVRQKVGSRLTVDELLRRMLGDSDNTAANMLIRAV-GE -ERLNATAKAMGDGAM--------------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. BNL1100 TaxID=755731 RepID=H2JBD9_9CLOT ----LKKLITDYTAGLSGKYGVTFIDLATGEMV-NVNDTDRYIAASTSKLPINVLLYKNVE -AGKVNLDDMLTYQKEDVEPGTGIIQKSAGTQYTVRETSKLAIRKSDNCGVNMLIRLL-DI -QNVRQYLVDLGGKVY--------------YDNRHRSCPYDMALVAQDLYKHYLKNQDVYG -ELINNLENTDW-HDRIDAQLT-GVKVAHKIGNQVK-TANDVGIVFAS--HPYVLSIMTDN -VD--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Prauserella sp. PE36 TaxID=1504709 RepID=A0A365Z6P9_9PSEU -----AESIAEHWREVGATGHLLARNLDTGEHL-GFDVDTPVPLASVAKVPLALVVLDRIA -EGDLDPALAITIDPATKSLPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV -EHVDRRLRDWGCTGIRIRHRMHRMYETLDPAHANVGSATALVELLQRCWLDEVSRPDATA -ELRRLMALQVF-NQRLSSDLRADVRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS -ARRAAHDIDLAIGAAARSAF--- ->[subseq from] Uncharacterized protein n=1 Tax=Planctomycetaceae bacterium TaxID=2026779 RepID=A0A2E3MXT9_9PLAN ---ELPRQIELLENKHAGTFSIEVQRLDADEHF-ALRAKTPLPTASTCKLFVLCELFRQAE -EGTIDLRAPISWKPEFHRGGDGVLRAMTGQELSIHNMAVLMIIVSDNIATATLVDLV-GP -DNVNRTMKSWGLAATNVYDGLPGGSNA-SRMKQPVSTAHDLCSLMTRIYRHDVLTPKSCD -EIIRIMRAQRC-NDMLPRYIPAKSWIANKTGYGA--CRVEVGVVRTTEV-TFSLAMFFKP -HQP-------------------- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Variovorax sp. TaxID=1871043 RepID=A0A519GLY7_9BURK --------------------------------------------------PVAIAVLRGIE -RNQFSLDSNVTLRASDYVDGAGPTKGYPVGTLTVRFLLEQMMVLSDNTATDMLIDLV-GI -SEVNAVTQSLVPEGFSDITTLSDVRRAYYAQGVNSARLDAYGELLARLVEGQALTPRWTA -YLIALMERVQTGTHRLKAGLPGGLRFAHKTGTQRY-RICDAGLIRTAAHQRRVLLVACTR -GDVPVERSEAALMQVGAAL---- ->[subseq from] Serine hydrolase n=1 Tax=Gordonia sp. i37 TaxID=1961707 RepID=A0A1V4PTD9_9ACTN -----ARNVAAIFADAGCAGWVHARVIGASQEI-DLGADHPVVMASVYKLTLAIAFAREVD -AGEIDASEQVLVDPRARPDGPTGLSLFGDPVLTWRDLVTSMMVVSDNAAADVVLERV-GL -ESIAAVLADAHTTHTTVVDGVRQVHAAYDAAYTSATTPRDCTRLLDCLWRDVLATPESSA -WIRRLMAQQVS-RSRIASGFSVGTRVCGKTGTIGP-IRNEVAVIEHPEEYTIAVAVFTRS -ARGDGPRVDVAIGAVARAVVT-- ->[subseq from] Beta-lactamase n=2 Tax=Candidatus Amesbacteria TaxID=1752730 RepID=A0A0G1UHV9_9BACT --kEIADKLRKRVEGLSGEYAVGVYRLKTGENY-GFNQRVEMPAASIMKVPIMTAVLREAE -AGSLKLEDTYILKETDKRYGSGPLELLKAGTVTVERMLSVMGKNSDNTAPVVLARMI-GW -DKVTETLEKLGMTNSDFE--------------MNTTTAEDVVEMWAKLYEGGIVAQDHRE -MMWEWLTESIY-EERIPAGVPEWVHVVHKVGTDA-GVWADAGIVECK------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3N544_9ACTN -----------------------------GPEV-AIRADEQVVIASIFKILLVLEFARQVV -AGQVDPGERVLVTAADRLGGWGLAGCADDTEVSLRDLAYFAMSVSDNTAADVLLRRV-GA -DLLPMLAAELGLARTRVLGGPRELVEVFDPAQTTSSTAREITRLLGLIWRDAAGPAPACA -MVRAWMARQLF-WTRLAAGFPPGVRVSGKTGTLP-GLHLEAGVAEYPDGRRYAIAVFARS -NETRRIDVDLAMGEAARTAV--- ->[subseq from] serine hydrolase n=1 Tax=Kocuria turfanensis TaxID=388357 RepID=UPI0009FD9B0A ------------------------------------------------------------- -------------------------DTVPGTAFTVREAVERMVTWSDNVSGAALGRWL-GW -HEVQAFAQGQGFESTTYDPDTGEAG-----TVAMTTTPNDVADLLDRLRGGELLSGPSTT -LLLGFLAAQEL-DYALSTGLSPDVEFAHKTGLLIQ-VSHDAGLVRLNGK-EYVVAVLTDG -WSG-------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Weissella sp. 26KH-42 TaxID=2506420 RepID=A0A4P6YSP5_9LACT --------------------------------------------ASTIKVFILAALLDQES -KGHIKLTQTYQLQASDKVGGTGILQGAASGSYSYKELANLMITQSDNTATNIIIQRLGGF -SVVNNYVQSLGYRHTKLQRKMMDLTN----QKNNMVAANEACDFLYKLYQGQLVDEQARQ -WFLQLMTQTTN-RQKFAAQGNNGITSYNKSGESSQGIQNDLAIVTRGKQA-YVVAGL--- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Prauserella sp. YIM 121212 TaxID=1477506 RepID=A0A318LXM6_9PSEU -----AESIAEHWREVGATGHLLARNLDTGEQL-GFDVDTPVPLASVAKVPLALVVLDRIA -EGELDPALPITIDPATKSVPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV -EHVDGRLRDWGCAGIRIRHRMQRMYETLDPAHANVGSATALVELLQRCWLDQVSRPGATA -ELRRLMALQVF-NQRLSSDLRADVRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS -SRRAAHDIDLAIGAAARSAF--- ->[subseq from] Beta-lactamase class A n=1 Tax=Trichococcus patagoniensis TaxID=382641 RepID=A0A2T5IDV1_9LACT ------------------------------------------------------------- ---------------------------QMADGATVADYLTSTITVSDNETAKELAYLI-GW -DNIEAFIHEQGFVSTNFHPYLESDGVYYNGDL--ETTPAEVAFLLERLLDGDLLSESSTA -YFLGLLADQQL-VYALNTGLDEGVTFAHKTGLLDY-VSHDAGILTLDGQ-TYIVAILTDG -WQDATNDATPVFESLGSAVMTY- ->[subseq from] Uncharacterized protein n=1 Tax=Kitasatospora sp. CB01950 TaxID=1703930 RepID=A0A1Q5EC63_9ACTN -------DLREIFERAGCEGALCVREVAGDGEI-VLDADRAMVSASVFKVQIALEMESAFV -DGRLDGRERVVLGAAERTFGPVGTSLFEDEVLSWRDLVVLMLTISDNPATDALLGRV-GV -DAVNATAARLGLSGTFVESDLRTMLDAMDPARGTRTTPRDMAELLRLIWTDGAGPAAACA -RVRKVMASQLT-RHRIASGFRPPVRVAAKSGSLLGVVRNEIGVVSFPDGRQYAAAVLTRS -PLSDDAAINRAIGEAARQAV--- ->[subseq from] Uncharacterized protein n=1 Tax=candidate division WWE3 bacterium TaxID=2053526 RepID=A0A3D0ZQB5_9BACT ---KTETQFSELTKKLPGVYGLYIKDVGSGREF-KYNDTTEFYAASLYKVPIGAAVLKEVE -AGKLNLDDTATYLPYDYSSGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY -KNVQETFNEI-----VPDKNTSTYY------RYNLSTPAEIGYVFEKLYFGGYLNDADKK -YLSDLMVHTSF-EDRISAYLREDLIFSHKIGSWPD-SWHDCGVVYTETKSELIVCLMSQR -A---------------------- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI0011A3837D ----LAADLEELAAGVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048D14C6 ------------LDRVPGTVSAYLARLDAAAPTwIRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-REDLAVGLPAGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG -DDPDHSPDEDACQLIADISAR-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NBS 11-29 TaxID=1960879 RepID=UPI000B7862C1 -------------DRAAGIVSGYVGRLGARPTW-SRRADATHYAASTMKVAVLVALHRAAE -AGRLDLDAPVPVRNSFDSALPGATWDAVGGTAPLRWLAERMIVRSSNLATNLCIGQV-GL -PAVAQAWTLAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGGLALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPADAPPYAIVVCTTT -DPADDDDACRLIADVSARVWA-- ->[subseq from] Serine hydrolase n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A357NIE0_9FIRM ------------------------------------------------------------- -----------------------------------PALVSDMIIYSNNEAFWELAEQL-GS -PTLETTCRDLGLRNTAIHNDAAYQR----TGYHSITTPRDMGKALEGLLRGRYIGNKNSK -TVLRLMENGVY-NEEIPRRLPPNTPVAHKPGELDD-ILCDVGIVFNAQR-PYLISVYTKS -NAGS-TAASNMIADIAAITDKYf ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=A0A495XGC4_9PSEU ------ARIRAAFADAGVTGRLHAVDLADPTRQvAVGADEPVVLASVFKLPLLVALYRS-- ---GIDLTRRVTLDPGDRSTPTGIGGLLDPVTMSLRDLAFLAITVSDNAAADALVDVV-GL -DEVNRVLRDLGLTRTAVVHRARDFMRALDPTRTNRGTAREMTSLLTHVFAEDVYEPIRRA -M-----SLQV-WPHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVSYPDGGRYAVAVFTRS -ASFTLPAADAVIGTAARLAVEH- ->[subseq from] Serine hydrolase n=1 Tax=Streptacidiphilus sp. DSM 106435 TaxID=2126346 RepID=A0A345SRK2_9ACTN ------------SAALPLTLAVAAVDVDGGRTV-GVDDTAVLPVASASKLLLLAEVSRRLD -SGELRADQVVDIPDQDVAGGTGLLRRLGRRGWTVEDLAWLTASVSDNTATNALLRLV-GR -PATARLARQLGLDHLTLHDSVRDVRGPDVPPVFATGTARDLARLVALTVRGTMASPAASG -RLLEWMRSNTDYAPCFPDPLPGGLLVANKTGTDT-GVRADAGVIIGARRVAYAVVAHWDV -ALSTERAAVHAIRDVGRTL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Xiangella phaseoli TaxID=1144548 RepID=A0A1H7D8P5_9ACTN ------DDLHARLDRAPGTISVYAGPLDAPPTW-VRHADATHYAASTMKLAVLAALHRAAE -AGHLDPDTPVEVVNRFTSAHAPPYWERLGERATLRWLAERMVVRSSNLATNLVIEHV-GR -PAVAQVWASAGARHSVTARGIEDFAAR-QAGITNLVTAADLAALLDAVATGAIASPASCA -AMLDVLCAQQI-RQDIAEGLPAGTRLAHKNGWVR-GVRHGAAVVFPDDAEPYLLVVCTTT -TLDDDQASEPADAAARRLVAD-- ->[subseq from] serine hydrolase n=1 Tax=Veillonella magna TaxID=464322 RepID=UPI0003F520DD ----LQTELDDIIKEYQATISYMVTIHNDDEYVvARNEDTVHASASMIKILIMLSVFEAVS -QQKLALTDQIALTATPRVEGGGALQELQGNHFSVLELCRLMMVLSDNWATNLLIRTL-GM -TFINDTAKKYGAAKTSLKRYMMDTAAA-ARGEENVTTAYDMIVLLDAIFQIREQS-VGGH -EMWQILGRQQF-RDKLPFHWGEEVPFHHKTGCLDR-VEHDGGILPLMNGN-FGLVVLISN -MDND--EAIQLTARMGR------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium RIFCSPLOWO2_01_FULL_36_13 TaxID=1798614 RepID=A0A1F6JL09_9BACT ----LSKIVEKNLENQGGSYAVGILNLTTGDEY-FKNKHQIFDTASLYKLWVMGLIYQKIE -NGTLQKNTVLSDSVENLNKASESAERKEGEVMSVENAIDLMITKSDNYSALLLSSYL-GI -SKIQLYLNEHGFSESKLGSSETLP----------STSVYDILQFFYKLYYGELADKEFSE -EMTTILRRQVL-NGKIPKYLPDNTEIAHKTGELGM-YSHDAGIVYSKNG-PYIIVVLSDA -NN--KKTADETIAQISKEVYNYf ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A378GZ73_KOCRO ----LAADLEELAAEVPGELGVVLLGPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGSSTA -LLMGFLEEQHF-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces hoynatensis TaxID=1141874 RepID=A0A3A9ZG80_9ACTN ----------------------------RGGEV-ALRADEQVVIASIFKILLVLEFARQAA -TGRLDPRERIRVRAGDRLGGWGVAGCADDAELSLRDLAYFAMSVSDNTAADVLLRRI-GL -DVLPLLTAELGLTRTRVRGGPRQLLEVFDPEHTTSSTAREITRLLELIWQDAAGPPAACA -AVRELMARQVF-WTRLGSGFPPEVRLAAKTGTLP-GLHMEAGVVEYPDGGRYAIAVFAAA -ESSRGIDIDLAIGEAARTAVEH- ->[subseq from] Beta-lactamase n=2 Tax=Clostridium intestinale TaxID=36845 RepID=U2N4T2_9CLOT -------EIKRYLESRIGNYSFYFEDLHSGYMY-SYNENVQMVAAGCMKLPIAVSLIKSVE -EGRFTFLDKIKIESKDKVYGTGIIHEFNEREYTIFELLVAMLIQSDNTAANKIIDLV-SM -EKINKDIKEMGLRSTILNRKTTDERSD-QSELENITSAYDLSKIWKHLYNGTFLNKENST -MVIDILRRQQI-KNKLALYISDDYDISSKTGDKK-GVENDTELIQLSKGN-FVFTILSMD -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Beta-lactamase n=1 Tax=Parcubacteria group bacterium GW2011_GWA1_Parcubacteria_45_10 TaxID=1618789 RepID=A0A0G1NMC7_9BACT --kEIESAFKEETKGLSGVYGLYVSRLDGSGSY-GVYEDDAFEAASLIKLPVLVALYKEAE -LGNVNLDEKYVLEESDKVGGAGSLQYKSAGTYSYRQLAQLMGNQSDNTAFRIVRNLL-GD -RKIQETANYLGMTKTSLSQN--------------ETSPRDVGILLEKLYGGQILSQESAS -EILNFLTNTLY-EDHLAAGIPSEIRVAHKYGREVH-VVNDAGVVFSD--KPFILVILSKG -VV--EPEADEVFPNLAKLIFE-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3L7YKX7_9CHLR ---------------YPFKTGWSFHDLVTGETA-NRFGDLVVPAASTRKVAILMTAMQSVN -RGELSLEEPVTIDERWQISDSGVFQFRPGFTITMHDVLLMMIIVSDNACTGIVCDRL-GL -DAINRFSQSVGMTGTVHREGIPQYTLSDARGTVNETTPNDVARLLHVILRASGVTPALAE -LALEMLSRQRL-RARLPFLLPGDTRVAHKTGTSGT-TYNDVGIVYRGDMPRFILAVYTSD -VPAIL------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Actinopolymorpha cephalotaxi TaxID=504797 RepID=A0A1I2QCC0_9ACTN ----------------PGRASVWFGRPGHPPAY-VREPDATHYAASTMKVAVLAAAYRLAD -EGLLDLDEQVPVHDDFESAGSSYHWALLGQSASLRWLARRMIVRSSNLATNLVLERV-GL -PAVAAAWSVAGARHSVVARGIQDYGA-EQAGLSNLVTAADLAGLLTALYDGTLASPQACA -QMLTVLLGQEV-TEDVVAGLPAGTPVAHKNGWVD-GVRHSAALVLPGDAPPYVLVTCVSA -DL-DEEAGCAVVARVAAATW--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536MVP4_9CHLR --dQLRSDLEAIARASGGRVGISLQELSGPRSL-SINGGQSFGAASTYKLVLLMAEAQQIA -SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP -DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG -WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG -LD--EGTAWSLVARVSARIWQY- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI000F6C6F06 ----LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSAA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora pallida TaxID=145854 RepID=A0A1C6RPI9_9ACTN --------LDARLAGVPGTVSAYVGRLDAAPTW-THAEHAPHYAASTMKVAVLAALYRAAD -AGTLDPDTPVPVHNDFPSADGPRFWQRLDRTAPLGWLAERMIVRSSNLATNILLGHV-GL -PAVAEVWALVGARHSVTGRGIDDAVAR-EAGITNLVTAADLAALLGALALGSLATPTSCA -TMLDVLCAQQI-RDDLPAGLPTGVRIAHKNGWVT-GVRHGVGVVLPDDAPPYVLAVCTTT -DLDSDDDACRLLADISAQVWA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sagamiensis TaxID=47875 RepID=A0A562WD94_9ACTN ---------DARLAAVPGTVSAHVGRPGADPTW-THAAHTPHYAASTMKVAVLAALYRAAD -AGTLDPDTAVPVHNDFPSADGPRFWQRLDRTATLRWLAERMIVRSSNLATNILLGHV-GF -PAVADVWTLAGARHSVTGRGIEDSAA-RAAGITNLVTAADLAALLGALAVGAVATPTSCA -TMLDVLCAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT -DLTD-ADACRLLADVSAQVWA-- ->[subseq from] Uncharacterized protein n=1 Tax=Marvinbryantia formatexigens DSM 14469 TaxID=478749 RepID=C6L8W7_9FIRM ------------------------------------------------------------- ---------------------------------TILSSLDAMITVSDNESSNVLVRQLCGL -AKVNDFIARYGFSSTQQVNGIADPSLWVSDGRVNMTSPADCGRLLEMIYNGELVSHFYSF -RFETLLNRQQV-NYKIPDGLPEGVHISHKTGEVDD-TENDAAIIYTPYGD-YIFCIMSTD -LT-DTDAAVEHIHEVTRLIYNYf ->[subseq from] serine hydrolase n=1 Tax=Ruminiclostridium cellobioparum TaxID=29355 RepID=UPI00048072F0 ---ELKKIITDYTSKLPGRYGVTYIDLATGEMV-NVNDQVEYIAASTSKLPINMVLFKDIE -AGKVSLEDKLVYKEEDLEYGTGIIQNSPYGTYTVRETSKLAIRKSDNCGVNMIIRQV-GI -ENVRKYLTDLGGKVYY--------------GKTHRSCPYDMALVARDMYSHYLDNEAVYG -ELIDNLENTDW-NDRISAKLT-GVKVAHKIGNQTK-TANDVGIVFG--KHPYVLSVMTED -VD--FGTACNNIAALSKKI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora krabiensis TaxID=307121 RepID=A0A1C3NDH2_9ACTN --------LDARLAEVPGTVSAYVARPGAAPTW-TRRADDTHYAASTMKAAVLAALHRAAD -TGTLDLDTPVPVVNDFASADAPRFWARLGDRAPLRWLAHRMIVRSSNLATNLVLAHV-GL -PAVADVWALAGARHSVTGRGIEDFAA-RDAGITNLVTAADLGALLGALATGALAPPAACA -AMLDVLAAQEH-REDLAAGLPPGTRIAHKNGWVR-GIRHGAGVVFPDDAPPYVIVVCTTT -DPDNDEDACQLIADVSAQVWT-- ->[subseq from] Beta-lactamase enzyme family protein n=1 Tax=Meiothermus granaticius NBRC 107808 TaxID=1227551 RepID=A0A399FBQ7_9DEIN ---SLSDELQAHIQAFPGQVGVWLEHLSSGETF-AHQPQRPFLAASTIKLPMLCYALATRA -----DLSQNIPIKPEVVALGSGVLKDLSPGLLPLRDLLTLMIVLSDNTATNVVLDHWGHK -EPFNAYYRAQGWSQTHVAGML-SLPERLPGD-AAKTSAQDLGRLLKALWRGELLPPDATK -TALDILSRQQF-TAFLRYLLADLIRLYSKSGEIRC-CRHDTGILARGEQA-LSITVLTET -ETHPDHPATLLIGRIAEVAYRYw ->[subseq from] Beta-lactamase n=1 Tax=Agromyces sp. Root81 TaxID=1736601 RepID=A0A0Q8VYG6_9MICO -----LRDAAEVLSSAGLRASIVVRDLGSGRQL-SIAADDAYPLASVVKLPLALAVLQLID -EGRLDPARPVTLEPADRTPQTGYSRFRHPTTVSIEDLLYMAVCLSDDTAADALFELC-PP -AEVTASLRETGIAGITVRHSIRELHRQLDVSSANAGTANACVELLDRIWRSPAFDG-QKD -RLRGLLAMNVM-RQRLAPDLEDDAAWHSKTGTFLH-LRHEIGVLEHADGRALAIAVLSES -SVQRQPAAEQALGLAAKLL---- ->[subseq from] Serine hydrolase n=1 Tax=Veillonella sp. T34266-5 TaxID=2027457 RepID=A0A2S7Z8V4_9FIRM ---SLEIQLAALLDTLDATVSYMVTRLNEGEEA-TIVASSKHTGASMVKTLILEYVFHLAA -QEQLDLNDTIALSRSPRVEGAGALMELVGNHFSYLELCRLMMVLSDNWATNLLMQAL-GM -ENINARAEQLGLEHFEINRMMMDFTAA-KENRENYITAMDMAVLLHHIYEL--RHTIYGH -EMWNILGRQQF-RDILPFHWGEDVVFHHKTGSLDR-VEHDAGIIETMNGD-FCFVLLMSH -LDND--KAKQLGA---------- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium 13_1_20CM_2_70_9 TaxID=1805058 RepID=A0A1Q8A6P7_9CHLR ---DLASALDQAAAGVPGMVSVVVVDVDSGYVY-ERRADERVEAASLFKLFVMAALYRRAL -DDPQLLEVIVPVSRPRLTAGQV---DYVLEPVAVREALEEMIDWSDNEATAALVELL-GT -DEVNATIASLGLRDSVVRSGEATGN---------STSARDIGRFLTLLARREVVAPEASD -AMTWLLLRQGI-NDRLSLGMPKDALFAHKTGNSA-GTFHDAGIAWTAWGE-RVLVVLTDG -VAPP--DARALMKDLG------- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Actinoalloteichus hoggarensis TaxID=1470176 RepID=A0A221VY31_9PSEU ----LNEHLQSELAVGGLRGGFLARDLTSGLQI-GFNENAVFASASLAKIPLAVAILDRID -AGVLDRAATVTIAPTPTGYGPPGLSSRHPATLAVEDLVYLSVALSDNTATDALFDLV-PP -ADVTAHMREIGILGIQVRHRTRDLQQQLDTSHANTGTAAGFTDLLQALWTPSLIPLRSSQ -HVRALMAGNVHRHRLTPDFVSDSSTWSSKTGTLLN-LRHEIGVIEHADGQTIAITALTQS -RIAQQPAADILIARTARALHDH- ->[subseq from] Putative endopeptidase p60 n=1 Tax=Moorella humiferrea TaxID=676965 RepID=A0A2T0AM18_9THEO --sSLKKQIEDFLATQAGTYGVYFKDLISGQSF-GINADMPLPAASTVKLPTVLFINHLVA -QGNLDWQQKLTYNSTDYQGGSGILQFSVKDGLTLRTLTTLAITTSDNIAYNMLRNFV-GK -ESVAAFMRSLGGQTVFP------------N-GQNLSTARDMATYVQAALDFAKVNPDGRR -LLDD-MANGIY-NEGIPLKIPDGVTVAHKEGFIW-GSPDDVGVVFG--SRPFIVTVLSQG -VD-DPDQGFANIATITRMMYDY- ->[subseq from] Beta-lactamase n=1 Tax=Bacillus nealsonii AAU1 TaxID=1202533 RepID=R9C9N7_9BACI ----LSKRINEIVQEYKAHGHFGITIEWKEKCF-YFNAKDVFPSASLIKLPILLEGFMQSS -SGTLVLDDLERVKDIQKVGGAGIVQYMSPQSLSVHDLLTLMIIVSDNMAANYLIERL-GM -DRVNRRCQQLRMSSTILQRKMMDQE-ARERKLENYTSPLDIIRCLKAIQNN------KNQ -SCKKILSHQQL-LDKLPYYFEENIRIANKTGELDK-VEHDCAIIEHEDE-IIYVAVLTDQ -LTTN-FKGKQIIQLIGASIL--- ->[subseq from] serine hydrolase n=1 Tax=Prauserella coralliicola TaxID=1401264 RepID=UPI000D93CD7E -----AESIAEHWREVGATGHLLARNLDTGEHL-GFDVDTPVPLASVAKVPLALVVLDRIA -EGDLDPALAITIDPATKSLPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV -EHVDRRLRDWGCTGIRIRHRMHRMYETLDPAHANVGSATALVELLQRCWLDEVSRPDATA -ELRRLMALQVF-NQRLSSDLRADMRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS -ARRAAHDIDLAIGAAARSAF--- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Streptomyces jeddahensis TaxID=1716141 RepID=A0A177HI62_9ACTN -------------------------------EV-AVDADDLVVIASIFKVLLVLEFARQVV -AGQLDPRERMRVTAADRLGGWGTAGCLDDVELSLRDLAHFAMSVSDNSAADLLLSRV-GL -DTVRLLGEELGLVRTRIVGGPRELLEVLDPRHTTASTPREITRLLQLIWSDAAGPPEACA -LVRDFMSRQVF-RHRLVSGFPDDVIVAAKTGTLP-GLHMEAGVARYPDGQCYAIAVFART -QDASRATVDAAIGKAAGI----- ->[subseq from] Serine hydrolase n=2 Tax=Chloroflexi TaxID=200795 RepID=A0A5N9BW42_9CHLR ---DLRSKVLGIIDDFSGTASVSANNLTTGEVL-SINEKKVLPALSAIKIGIMAELFFQIH -EGEYNLLDRVKIDASDLRGGTGVFREMETPFVTLKDICMMMIVVSDNTCTWKLSSML-GI -DSINKRMRSLGLNEYSLNHDLPTAFDDMQGKDVNECSARDFTNLVTLMAKGELVSKESSD -AMLDIMGRCQH-IEWLGRYLPPKVKMYNKLGAYLH-ARCDTGLIKSENSD-YVITVFASY -SKDKPHEGSRLIGEISKAVYDFw ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Woesebacteria bacterium RIFCSPHIGHO2_01_FULL_37_10 TaxID=1802489 RepID=A0A1F7XY25_9BACT ------------TENLSGVYTLYLVRLGNGSNY-GVNEKDAFQAASLIKLPVMAAMFTEVE -EGRLSLSSKYKLKSSDKVKGSGSLYNKPPGYITYENLIKLMGKESDNTAFNIGRKYL-GD -EKIAEVIGKIGMKNTSLE--------------ENSTTSEDIGVFFQELWNGNTLNNDHKE -MLLEYLTDTIY-ENWLPSGIPEDIRVAHKFGRELH-VVNDAGIVYAND--PFVMVMLSEG -IV--EKEADLVIPEIASGIYE-- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Clostridiales (miscellaneous) TaxID=39779 RepID=U2D0X1_9FIRM --dDIQQKVKQYLGNNISKVGIGYYDIETGKGF-SINGDKYFTAASTVKVQMNMILFDMIR -EGKINIDETVKYSQDDYEGGTGVLQGEDKSKIPIQKLSDYSIMYSDNIATNMIIRKI-GY -SEMKRFADKLG--------------HSIPQD-ENVVTPNEELAFLKMLYNNKG-NNTYYA -RLISIMKTTVF-HDRLDKYVPQN-IVAHKVGDYGE-FINDVGIVYSS--KPYIIAVYTKN -LS----NANEIIANINKIIYNY- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora avicenniae TaxID=1198245 RepID=A0A1N7EMN9_9ACTN ----VAESIAEQWQQVGAGGHLLARNIDTGEEL-GFDIDVAVPLASVAKVPLALVVLDRIA -AGELDPAMPVTIDPATKSLPTGVAAFRYPATLAVADLIHQMLTVSDNASADALLDLV-GV -GAVDERLRAWGCGGIRVRHRMQRMYETLNPAYANVGSAAALVELLQRVWLDRISRPEATA -ELRRLMALQVF-NQRLSSDLRADVRVSGKTGSFLH-LRHEIGVVTTESGERVAIAALTRS -HRRAAHDIDLAIGAAARSAF--- ->[subseq from] serine hydrolase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E2620D5 ----------------------HVREIDGTAEV-AHRADEPVVLASVAKILIVLEFARQAA -TGRIDPAERVVARRADRLGGTGIADFADDVELSLRDCASLAMTVSDNTAADLIVDRI-GV -EPVRLLTEELGLDHTRFTGGPRSLLHTYDPARATSGSMRDLTLLLSLIWTDRAAPPDACA -FVRALMARQLV-RARIASGFPPPTRVSAKSGTLP-GLRQEAGVVEYPDGRRYAVAVSATV -TDPDHPETDLALGRAARSAV--- ->[subseq from] uncharacterized protein LOC111363712 n=1 Tax=Spodoptera litura TaxID=69820 RepID=UPI000C1429B2 ------------------------------------------------------------- ------------------------------------------------------------- ---VNDYIHKIGIKEIAIVASEEDMHKAWDVQFGNWTKPMAAVELLKIFYDKKVTSKANFD -FLWKVMLDSPTGKKRIKSQLPEGTLVAHKTGTSGTNAVNDIGIVTLPNGKHFAISVFVSN -SKENEETNEKIIADISKLAWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Catellatospora citrea TaxID=53366 RepID=A0A419XCJ5_9ACTN ------AEAREALRDAGLRGSFLVRDLDSGQEM-GIDADVVWPVASLVKVPIAVATLERAA -RGELDPAAPVTVQPGRVSTPTGLTRFRHPATLAVEDLAYLAVAVSDSTAADALLALT-GP -AQVTAELRRLGVAGISVRYLMRELASQLDIARANTGSARAFVDLLHALWRPSTMHTAVAE -RVRELMGATVM-RHRLAPDFSSDASVSSKTGTLLN-LRHEIGVVEHADGQTFAVAALTES -SVAVQPEAEALMAHVARTLRD-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. sk2.1 TaxID=2478959 RepID=UPI0011E86013 ------------SAALPLTLAVAAVDIDGGGTV-GVDEHTVLPVASASKLLLLAEVAHRLD -GGELAADRVVEVLDEDVAEGTGLLRRLSGRDWTVEDLAWLTASVSDNTATNALLRLV-GR -ESTARRARELGLDHLTLHDKVRDVRGPDVPPVFATGTARDLARLVAHAVRGTMSGPAASA -RLLRWMRANTD-HGLVPALIDDGLLVANKTGTDT-GVRADAGVIVGRRRLAYAVVAHWDT -ALSTERAAVHAIRDVGRTL---- ->[subseq from] Serine hydrolase n=1 Tax=Kibdelosporangium phytohabitans TaxID=860235 RepID=A0A0N9I1B4_9PSEU ----TVETINARAEEVGVRVRLHAAEIDGTRQI-GIEGGVPVVTASVFKVPIALELARQAA -DGGLDLGELVTVAPGHPTPPCGLATFRHEVTMSWHDLAILMIGISDNVATDLILARV-GN -QAVGHSLRRMGFEHTTVTQDCGEILDALRPEHTCATTAEEITRLLGLIWRDEAASPAACA -DVRRWLELQVW-PHRLRSGFPDDIRVSGKTGTLPS-VRNEVGVVEYSDGGRYAVGVFTDA -VDSRVPERDAFIGFAAARA---- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A350T083_9CHLR ---DIERDARALIDAFDGDAAFFAQNLLTGEEV-GFRADSVMPTASTIKLLVLAEVIRQAE -AGQFALDDPLPMISEDQSGGSGILKDLSPATLTIRDHATLMIALSDNTSTMALVRLA-GR -ARIEQAGQEWGMTATTLP-----IDRAPDGDARDYSTPRDIVHLLQLIATDALVSPAASA -TVRDILVTQQY-HDQIGRYLPYNIVVRSKSGFMTDSVRVDAGIIEISGVQRYVLCLMTEH -HP--------------------- ->[subseq from] Serine hydrolase n=2 Tax=Kribbella sindirgiensis TaxID=1124744 RepID=A0A4R0HZJ5_9ACTN -----NARIRGIFEDAGVRGWMHAISLDDPEARvELDADVVVPLASVYKLPLLAGFSRLVD -LGELDPREQVTLEPSSRTAGPTGLSMFADPVVSLRDLALSMATVSDNAAADALLDIV-GL -RRLAGILESFGLRRTWVRRGTAANLRVYEAASGSAASARDLTLLLRRLWAGELLSAEQTE -FVKATMHRQIF-LQRVASGFPDGVRIAGKTGTFG-ALRHEAAVVTLPDGAAFAIAILTLA -ARGDQPRVEAAIGEAARVAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Thermoclostridium caenicola TaxID=659425 RepID=A0A1M6C769_9FIRM ---ELRAMVEDFIGKQSGRYGVTFIDLATGESF-GINDKEEYIAASTSKLPMNLLLYIKIE -SGEVDPDMMLEYKPSHLEYGTGIIQNSPYGTYSVRETSELSLRKSDNCGINMIIELL-GI -ENIRQYIVDLGGV--------------VYYDKRHRSCPYDMALVAQELYRRYLSNPAVYE -KMIEDLENTDW-SDRIDALLPDHVRVAHKIGNQTR-TANDVGIVFAS--HPYVLSVMTEE -VD--FGTACKKIAEMSKMIYE-- ->[subseq from] Putative beta-lactamase (Class A) n=1 Tax=Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) TaxID=367928 RepID=A1A306_BIFAA ------------------------------------------------------------- ------------------------------EDASLDGLLEQMITVSSNEATNALVERLGGF -GVVNSVAAQYGFNESHLNSRMGDLSNY----STKQTSVADQGRFLAAAYRGQLVSAGYSK -RMTDIMSRQTR-RAKIPAGLPQGVACANKTGEAP-GVENDSAIVYG--EHPYVIAVMSSD -VP-DSSAAQAQIRDISSTVWA-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. B006 TaxID=2201999 RepID=A0A385AUQ9_9ACTN -------ELDAHLDKVPGTVSAYVGRPGAGPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALAPPSACT -AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus cereus VD142 TaxID=718224 RepID=J7T5F2_BACCE -----------------------------------------FMHPSTVKGLVTRVLLLQYP ---IKKLDEVITYTKDDLVEYSPSAEKHVDTGMTLREIAEATIRYSDNTAGNIL----DGP -KGFEKALKQIGNKVTMAACLEPALNEAIPRDIHDTSTAKTFATDLKAFTVRDALQTDKCK -IPTDWMRGNAT-E----------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase n=1 Tax=Streptomyces sp. ADI95-17 TaxID=1522759 RepID=A0A3N6EJH8_9ACTN ------------SAALPLTLAVAAVDIDGGGTV-GVDEHTVLPVASASKLLLLAEVARRLN -TGELPADRLVEVLDEDLAGGTGLLRRLSGRGWTVEDLAWLTASVSDNTATNALLRLV-GR -ESTARLAQELGLDHLTLHDKVRDVRGADVPPVFATGTARDLARLVTHTVRGTMSCPAASA -RLLRWMRANTD-HGLVPALVDHDLLVANKTGTDT-GVRADAGVIIGRRRLAYAVVAHWDT -ALSTERAAVHAIRDVGRTL---- ->[subseq from] serine hydrolase n=1 Tax=Clostridium tertium TaxID=1559 RepID=UPI0012C70E5C ------KEIKKYLESRIGTYGFFFEDLKSGYIY-GYNENVQITAAGCMKLPIAVSLIKAVE -DKKLDFLDKIKIDGKDKVYGTGIIHEFNEREYTLFELLVAMLIQSDNTAANKIIDIL-TM -DKINENIDEMGLKNTILNRKTTDER-NSKDEIENITSALDLSKVWKHLYNATYLNKENSQ -MLIDILMRQQI-KNKLALYIPDDYEISSKTGDKA-GVENDTQLIRLSKGN-FSFTVLSMG -IPNS-VYGTVTLAKCGKMMWD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536PR82_9CHLR --dQLRSDLEAIARASGGRVGISLEELSGPRNL-SINGGQSFGAASTYKLVLLMAEAQQIA -SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP -DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG -WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG -LD--EGTAWSLVARVSARIWQY- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536H9S2_9CHLR --dQLRSDLEAIARASGGRVGISLEELSGPRNL-SINGGQSFGAASTYKLVLLMAEAQQIA -SGQGRDSDLLCYAASDAEDG-WFMDYQPGSCYTRGELARRTGRYSDNTAAHILVRYLGGP -DALNRYAKSIGMNRSAL--WVP-----------NTTTPDDLSQAFVSEALGQLGGAAAQG -WLYPILTHTAT-EQGVPAGLPAGSTVVHKTGTMT-GTENDAAYVRNG-RIAYVLSVTVDG -LD--EGTAWSLVARVSARIWQY- ->[subseq from] Uncharacterized protein n=1 Tax=Blautia hydrogenotrophica (strain DSM 10507 / JCM 14656 / S5a33) TaxID=476272 RepID=C0CNH6_BLAHS ------------------------------------------------------------- ----------------------------------LNHLLELMITVSDNEAYNELMRRLGGC -QRVNQYLEREGYENTEVHHTLHPSSSASLGDGSNLTSVKDCGKLLERIYYGDCVSETASV -KMLKWLCRQQT-DWKIPAGIPKGIQIANKTGETDT-CQHDIAIVYAPSTT-YLLCVMSCE -LL-SENEGISRIQQLSAQVYEYf ->[subseq from] Serine hydrolase n=1 Tax=Mumia sp. Z527 TaxID=2585212 RepID=A0A5C4MGF7_9ACTN ---------------------AYRLATAAGDVLaERAATTPFYAASTIKVAPLVAALRLVE -AGTLTLDDTLVTRDTSQVPEAPDYG-MPPAGMRLADVLERMIVVSSNEATNMVVERV-GL -EAIAQVLSDAGAHDSRMTRQFGDQAAAEAYGMSNVVTAADLASLMGALVSGRLAGPHATT -WMTDVLSRQQT--PHIAANAPEHLPWGSKSGSVD-AIRHDVAYLGPPGAGTVVMAVCTRG -YP--AEDADETIAALGDLA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Candidatus Kryptobacter tengchongensis TaxID=1643429 RepID=A0A656DDR1_9BACT ----------------------------------------------MIKVPILVELFYKFE -EGKLKKDTLVSLEDSLKYGGSGVLQYFYDGAIKLIDAAVLMIILSDNTATNLVLDCFANL -DAVNNRMKELGLDNTKILNKLMSFKTKKKTPEAGYTTPNDMVKLLELLANGKIINPNVSA -EIINIMKNNQD-YEMMKRYLPENIVVANKSGSIDR-MKADIGIVYAKCT-TYAVAIFCDE -LSTVDNKGHLAVAEISKLIFDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora matsumotoense TaxID=121616 RepID=A0A1C4U2P8_9ACTN --------LDARLDRVPGTVSAYVGRLDAPASW-TRTPDATHYAASTMKVAVLVALYRAAE -AGTLALDAPVPVVNEDSARDAPRFWERLGGQATPRWLADRMITRSSNFATNLLIDRV-GL -PAVAEAWRLAGARHSVTGRGIEDAAA-REAGITNLVTPADLAALLGGLAAGPLASPAACA -AMLDVLLAQRH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVLPDDAPAYVIAVCTTT -DLDDLDDACRLVAEISATAW--- ->[subseq from] serine hydrolase n=1 Tax=Kitasatospora mediocidica TaxID=58352 RepID=UPI000559D0F7 -----TDDIREIFERAGCEGALCVQPLEGDAEV-GLLADEPVVPASVVKVQVALEAETWFV -EGRLDPCERVTLSAADRTPGPVGISLFNDDALSWRDMVVLMLTISDNDTTDALLRRV-GV -GALNATATRLGLTGTVIESDLRTMLDALDPSQGTRTTPRDMVDLLRLIWTDQAGPAAACE -RVRAAMARQVT-RHRIASGFRLPVRVAAKSGSLAGVIRNEIGVISYPDGRRYAAAVFTRS -RPSDDAAISRAIGAVTAQA---- ->[subseq from] serine hydrolase n=1 Tax=Kocuria indica TaxID=1049583 RepID=UPI00138ED5F4 ---ELHDDVATMLHAADMTGAVSVRVIGSDRSF-NYRAGVRFPMASLYKLVVMAAFCQAVD -DGLIDPAAPVELVPETRVPGPTGLSICLDPVMSWRDLVRLMMTISDNTAGNAVLCAV-GL -DRVAHTLRRLGLLQTDIRPYLPATDLEYDPLLVSSTTTSDLVDLLSFIWEDHAATPSQCS -FMRHVLGQQAWGHRFAEVFTYPGVQIAAKTGSLA-ALSHEAGVISHPDEPPIAVAVLTQS -ARRTIPLSNTVVGQIARHCVRSy ->[subseq from] Beta-lactamase class A n=1 Tax=Anaerobacterium chartisolvens TaxID=1297424 RepID=A0A369B956_9FIRM ---EFKSELEDYVSTFKGQYGIYFWDLNTDISF-GINESDEYLAASTVKIPINLYLFNKIK -DGEIDPEEKLVYTKSTDYEGTGIQYQNDGTEYTIRELSALSIRESDNVAVNMLIRKL-DR -QNYKDYMKQSGGVVV---------------TEKNESCPSDMALYMKAIYDFYNENPDVGG -ELIDSLQSTIY-NDRIPKLLPKAVKVAHKVGNQL-GALHDIGLVFAD--RPYVIAIMSKN -IN--EEEGYDVIANISKKVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. WN036 TaxID=2032628 RepID=A0A2A2G5P1_9MICC ----LAADLEELAAGVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTV -LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] serine hydrolase n=1 Tax=Nocardiopsis quinghaiensis TaxID=464995 RepID=UPI0012394F2B ------------------VVRVHAREIDGTGQV-GRLADEPVVLASVAKVLIVLEFARQAS -TGLVDPTERVVVRRDDRLGGWGTADFADDVELSLRDCALLAMTISDNTAADLIVDRV-GV -EPVHLLATELGLERTRFTGGPRALLHARDPSRTTSSTPADITRLLRLVWTDAAAPPRACA -FVRDLMARQLV-RTRIASGFGPDVRVSVKSGTLP-GLRMEAGVIEYPDGGRYAVAVCAAG -PDRTALEADMALGRAAREAV--- ->[subseq from] Beta-lactamase n=1 Tax=Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) TaxID=369723 RepID=A4X9J3_SALTO ------------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFDSAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTN -DDPDHSPDEDACQLIADISAR-- ->[subseq from] Beta-lactamase n=1 Tax=Bifidobacterium adolescentis TaxID=1680 RepID=A0A1X2Z9V0_BIFAD ------------------------------------------------------------- ------------------------------EDASLDGLLEQMITVSSNEATNALVERLGGF -GVVNSVAAQYGFNESHLNSRMGDLSNY----STKQTSVADQGRFLAAAYRGQLVSAGYSK -RMTDIMSRQTR-RAKIPAGLPQGVACANKTGEAP-GVENDSAIVYG--EHPYVIAVMSSD -VP-DSSAAQAQIRDISSTVWA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora zamorensis TaxID=709883 RepID=A0A1C5IKP7_9ACTN -------DLDAHLDRVPGTVSAYVGRPDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAD -AGTLDLDAPVPVVNEDSAQGAPRFWDRLGGTASLRWLADRMIVRSSNLATNLVIGHV-GL -PAVAEVWARTGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGRLASPAGCT -AMLDVLIAQEH-REDLAAGLPEGTRIAHKSGWVR-GVRHGAGLVLPDDAPPYLITVCTTT -DLEVEDDACRLLAHISAQVW--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V7AFJ4_9BACT ---DLVKRLNALCDGMPFQTSWYLKDLGSGAQA-DRLGAVPVPSASTRKTSILMSALAAVH -AGKLALDQKVTIEARYQDNDSGTFQFLTPGFITLRDALVMMIIVSDNTCTGLVVDLV-GL -DNVQRYCDAVGMKSTIHRYGMPKLSVGHSLEQVTTTTPQDQGLLLELILKGTQCTRELCR -LGLDILSWQRL-KTRLPSQLPLGTRVAHKTGTGPR-GYNDAGIVFKGDRALYILTAFTEN -VPAAFAAAYQVIGRMARMAWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Clostridium sp. DSM 8431 TaxID=1761781 RepID=A0A1I7G8W4_9CLOT ------KEIKRYLESRMGKYGFYFENLTSGFVY-GFNEHKQMTAAGCMKMYIAVSLIKAVE -DKKVDFMDKILVNRDDKVYGTGIIHEFNEREYTVFELLVAMLIQSDNTAANKIIDLI-GM -EKINSDIKEMNLKNTFLNRKTSDERNS-SYGIENITSAYDLGLLWKKLYRGEFLERDNGI -MLIDILTRQQK-KNKLALYIPDDVEISSKSGDKK-GVENDTELINLDKGE-FTATILSEG -IPN-SVYGIMTLAKCGKMIWD-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535YJM7_9CHLR --------------DPDGDYAVVMEDLKSGARV-AVNESQVFPSASLYKLGVAWMVLRQVD -TGMLHLDGPLDIAEPDTIEPEPDGGVAAGDRPTVREALADMLTISSNAAAHAFLRTL-GR -VDFNREMQRIGLSQTRIPEDVDADG--SDGDAQAVTSAADIARLLRLMATSQQLSAAARD -VLSECLASGAP-PDALRETLPAGIDVLEKTGNLDD-ASNVGALLQSARGT-VILVVL-DH -AV-DPGDARAVIAQAGQVAYK-- ->[subseq from] Serine hydrolase n=2 Tax=Kribbella sp. YM55 TaxID=1572660 RepID=A0A4R0IIP0_9ACTN -----NARIRGIFEDAGVRGWMHAISLDEPEASvELDADVVVPLASVYKLPLLAGFSRLVD -LGELDPREQVTLEPASRTAGPTGLSMFADPVVSLRDLALSMATVSDNAAADALLDIV-GL -RRLAGILESFGLRRTWVRRGTAANLRVYEAANGSAASARDLTLLLRQLWAGELLSAEQTE -FVKATMHRQIF-LQRVASGFPDGVRIAGKTGTFG-ALRHEAAVVTLPDGAAFAIAILTLA -ARGDQPRVEAAIGEAARVAVD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. Ncost-T10-10d TaxID=1839774 RepID=A0A1C5CLG0_9ACTN -------------ATLPLTLAVAAVDIDGGETV-GVDDRTVLPVASASKLLLLAEVSRRLD -TGELLADRPVEVLDEDVADGTGLLRRMSRRGWTVEDLAWLTASVSDNTATNALLRLV-GR -ESTARVAKELGLDRLTLHDKVRDIRGPDVPPVFATGTARDLARLVTHAVRGTMSSPAASA -RLLEWMRANTD-HGLVPALVDDGLLVANKTGTDT-GVRADAGVIVGARRLAYAVVAHWDP -ALSTQRAAVHAIRDVGRTL---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces yanglinensis TaxID=310779 RepID=A0A1H6DLY5_9ACTN -------TLAELFDRLGCEIALCVQALDGAAEF-TLAADRQVTPGSTMKVQVALEAETWFA -EGRLDPREQVALPAEGRTPGPVGLSLFADEALSLRDMVTLMLTISDNPSTDALLRRV-GT -GAVNATAARLGLTGTVVTSDLATLVDTLSPTTGTRTTPYDMARLLRLIWTDQAGPPEACA -RVRAVMARQLT-RHRLAAGFRRPVAVAAKSGSLLGVVRNEIGVITHPDGRRYAAAVFTRS -RPADDAAVNAAIGTAAARAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A3C0XPI1_9CHLR ----------------------------------THDDNVAFISASLYKLGILAHVESLVD -AGTLRYTDTIEIQPEDITDGS---YELAGTVMTVDEALEAMITVSDNGTALAFWRSL-GP -DNINATMQTLGLGDFHIANDD---------SDDNTATARVIGRYFTLLAQRKLVSAAASD -RMLARLERQQV-NDRLPSELPDGTVVAHKTGNLGF-ATHDAGIIYTPSGP-RVVVGMTAN -GDE--EEA--------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides terrae TaxID=574651 RepID=A0A1I1LH78_9ACTN -------------------VSVWLADLDGTVRQ-AQNVNHQHYAASLVKLPIALAAYRMHD -RGELDLDAVVPVHPDFASAVEGERETWAADTVPLRELVARSLARSGNLAANLVLEQV-GP -AEVAAVLADAGCSMTEVGRAIEDAPA-EEAGLTNLMTAHDAGRLLAGIAERTLASAAACQ -EVEQVLTRQRH-RDGIPLGLPEGTAVANKTGWVD-GVRHDIALVRPDDRPGFVLAILTSG -LDD--DEAEWRISELARFLWQ-- ->[subseq from] Uncharacterized protein n=1 Tax=Firmicutes bacterium TaxID=1879010 RepID=A0A3B8K7B9_9FIRM --------LEREIQKSRFKISLCLYDFQTKQWV-EKNAGQTLYPASLIKLLYLLTALEQLE -RGILSLTDKHILTDADKYVGSGSLQAEIGSSYTVAELLRLMISASDNIAANIVLDLV-RP -EAVSAMAARLGLTKTRGTRKMYALESSLP---PNLSTARELTELLVALENKQVCGEGLKN -LAVSMMLETEN-KQRIGRYIHKDALVANKVGTVDH-MVGDMALLYFPHRPPLALTIMISL -SPCRLAVVNAMARRAAGAA---- ->[subseq from] Serine hydrolase n=4 Tax=Bacteria TaxID=2 RepID=A0A2I1NZU8_KOCRH ---QLGREVAEILQSEDMTGAVSAIDAPELPVF-SFHEEEVFPAASLYKLAVMMAFCREVD -HGVLEPSALVDLSPADRAQGPTGLAILEDMVISWRDLVRLMMSISDNAAAEAVLRKV-GT -SRVHETLRLMGATRTEIRPTPPSGNGEYDPLSVSSTTASDLVTLLCAIWQDRAASAEQCA -FMRQVLSQQAWGHRFAEAFSYPGVTVAAKTGSFGS-LSHEAGVVSHPGEKSIAVAVLTRS -VRRQIPLSNKVVGQIARHCVRNy ->[subseq from] Serine hydrolase n=1 Tax=Nocardiopsis sp. CNR-923 TaxID=1904965 RepID=A0A1Q9TM45_9ACTN ------------------TLRVHAREIDGTAEE-AHRADEPVVLASIAKILIVLEFARQAA -TGRLDPAERVVARQEHRLGGIGTSDFADDVELSLRDCAALAMTVSDNTAADLIVDRV-GV -EPVQLLAAELGLTGTRFTGGPRSLLHDYDPARATSATPRDLTLLLSLIWTDRAAPPDACA -FVRALMARQLD-RSRIASGFPPAVHVSAKSGTLP-GLRQEAGVVEYPDGRRYAVAVSATV -TD--------------------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. BL1 TaxID=2478709 RepID=UPI000EF57655 -------ELDAHLDRVPGIVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEASLRWLAERMIVRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Beta-lactamase n=1 Tax=Agromyces cerinus subsp. cerinus TaxID=232089 RepID=A0A1N6E7S3_9MICO -----LRDAAEVLSSAGLRASIVVRDLGSGRQL-SIAADDPYPLASVVKLPLALAVLQGID -EGRLDPARPVTLEPAERTPGQGYSRFQHPTTVSIEDLLYMAVCLSDNTAADALFDLC-PP -AEVTASLRETGIAGITVRHSILELHRQLDVSSANAGTASACVDLLDRIWRSPSLGGQ-KN -RLRSLLAMNVM-RQRLAPDLEDDAAWHSKTGTFLH-LRHEVGVLEHADGRALAIAVLSES -SVQRQPAAEQALGLAAKLL---- ->[subseq from] serine hydrolase n=1 Tax=Ruminiclostridium papyrosolvens TaxID=29362 RepID=UPI000E3DEF25 ----LKKLITDYTAGLSGKYGVTFIDLATGEMV-NVNDTDRYIAASTSKLPINVLLYKNVE -AGKVNLDDMLTYQKEDVEPGTGIIQKSAGTQYTVRETSKLAITKSDNCGVNMLIRLL-DI -QNVRQYLVDLGGKVY--------------YDNHHRSCPYDMALVAQDLYKHYIKNEAVYG -ELINNLENTDW-HDRIDAQLT-GVKVAHKIGNQVK-TANDVGIVFAS--HPYVLSIMADN -VD--------------------- ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F8D086_9BACT --kKISEEFKNITKNLSGVYGLYVIRLNGEGAY-GIFDKEKFEAASLVKLPVLATLYKEAE -AGNIDLDTKYSLKNSDKITGSGSLSGKPAGTLTYRDLARFMGKQSDNTAYGIIKRIL-GD -AKINKEISDLGMTNTSLSD--------------HSTSPYDTGIFFEKLYKNQIVKEKYKN -EILDYLTDTIY-ENWLVAGIPEEIRVAHKYGRELH-VVNDAGVVFTK--EPFILVIMTKG -VV--EREADEFFPELTKVIYD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A1C4VU92_9ACTN -------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGVDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDDTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] serine hydrolase n=1 Tax=Granulicella sp. S156 TaxID=1747224 RepID=UPI00131B8F44 --hELLAQLQPILSAHHGKVALYAVQLNTGKTV-GIDQSLPVQTASDIKLAILYEAMVEVR -EGKAHWDEKLVLKPGDPVSGSGVLLFFDTPIVTLKDALTMMVIVSDNTATNMMIDRF-GV -DPVNARMVALGLTNTHLYKKVMKPATDQPKFGLGKTTPYEMAVLMTRIGRCELH------ ------------------------------------------------------------- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RIFCSPHIGHO2_01_FULL_42_12 TaxID=1798377 RepID=A0A1F5Z5D4_9BACT --dELAQVVRKAMQGTTGDYAIVIKNLKKGVSY-SQNENKLMHAASLYKSWLVTAVYEDIR -DGKLLEDQKLRESIPGLNNYFVIAPEELSSGMTVKQAVEQTITISHNYTALALLKNVGGY -DRVEKVLDEFGLANSTFK-------------IRPQTTAGDMAIFLEKLYKREIGDEQISE -KLIEVMSRNKL-NEGLPKYLPNKVTVAHKTGEIMT-YKHDAGIVYAPAGD-YLIVAMSDS -LS--TFGAEERIAQISRAVYDYf ->[subseq from] Carbapenem-hydrolyzing beta-lactamase Sme-1 n=1 Tax=Planctomycetes bacterium Pla108 TaxID=2528001 RepID=A0A5C6A2P2_9BACT ----LPNQIAELVESTPARVGLCVVHASGAPGF-GYREEEVFTQASAIKIPILGTLNRLAA -DGRLALSETLPVDPSDGVGGCGVLQNFLPGALALADLATLMIVLSDNVATNLLIERI-GF -DAVNELIEDHGSEATRLRRKMIDLEAR-KVGRENTATPRDAAVHMLRLAENANAGDPAAL -ATRRTLRLKKE--SPVTAALPKDLLLATKPGMLD-GLRTEWSLVQDEGGVDYAMALMADG -AD--DAVLEPLFRRLAAT----- ->[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI000490EB7F ------------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFDSAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG -DDPDHSPDEDACQLIADISAR-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6X6B3_9BACT ---DLVKRLNALCDGMPFQTSWYLKDLGSGAQA-DRLGAVPVPSASTRKTSILMSALAAVH -AGKLALDQKVTIEARYQDNDSGTFQFLTPGFITLRDALVMMIIVSDNTCTGLVVDLV-GL -DNVQRYCDAVGMKSTIHRYGMPKLTVGHSLEQVTTTTPQDQGLLLELILKGTQCTRELCR -LGLDILSWQRL-KTRLPSQLPLGTRVAHKTGTGPR-GYNDAGIVFKGDRALYILTAFTEN -VPAAFAAAYQIIGRMARMAWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8JXQ9_9BACT -----------------ARLGISAVLFDKRADI-SFNEDARFPMASVVKVPIAMLIASEIA -NGALSLHETITIHPRAFSPTNPIDRFYFATVYTVEQLMAFMIHASDNTATDAILNRLGGT -CAVMKFLFASDIEGISVKRTMHELLTHLIDSGEETCTPRAIVQLLKLLAMN-----PRYA -LVYSNMEHCAN-RQRIAVGLKEHKSLGHKTGSVG-AIANDVGIIHFNNGCFAALAVMTCH -STVRISVRDEQIATVTRTIVSQw ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. (strain ATCC 39149 / NRRL 15099 / SCC 1413) TaxID=219305 RepID=C4RKI1_MICS3 -------ELDARLNALPGTVSAYAGRVDAPPTW-TRRPDATHYAASTMKVAVLLALHRATE -AGTLDLDAPVEVRNESALPGAPRFWERESGHVPLRWLAERMIVRSSNLATNLCLRHV-GL -PAVADAWAIAGARHSVTGRGIEDFAAR-EAGITNLVTAADLAALLGGLAAGALASPAGCT -AMLDVLFAQEF-REDLAAGLPDGVRVAHKNGWVR-GVRHGAGVVYPPDAPPYVLVVCTTG -DPEAADDTCRLLADISARVW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora cremea TaxID=709881 RepID=A0A1N5YFF7_9ACTN -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHADATHYAASTMKAAVLAALHRAAE -AGTLELDAPVPVVNQDSAQGAPRFWDRVGGTAPLRWLADRMIVRSSNLATNLVLGHV-GL -PAVAQVWALAGARHSVTGRGIEDFAAR-EAGITNLVTAHDLAALLGALATGQLASPAGCA -AMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYVIAVCTTT -DLEDEDDACRLIAHVSAQVWA-- ->[subseq from] Beta-lactamase class A n=1 Tax=Kribbella sp. VKM Ac-2527 TaxID=2512215 RepID=A0A4R6KGT1_9ACTN -----------------GEFGVWLGRLDGVAVF-EHQAERTHYSASTMKLPVAIALMRKVA -AGELALDQPVIVRNDFASAEAPATWTKLGTPVELGWLATEMITLSSNLATDLVLECV-GV -DAANAVLTEYGSGRSAIRRGIDDRVAQ-AAGISNEMSPADLAAVLVAVGNDKT---AGGE -YVRDLLAGNQW-NGEIPAGVPAGTRVEHKNGWDTR-IRHDGGIVYPPDAEPFVLTVCTTS -ELPD-AEAQRLIASIATGAWN-- ->[subseq from] Uncharacterized protein n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A359KPR0_9CHLR ---DIERDARALIDAFDGDAAFFAQNLLTGEEV-GFRADSVMPTASTIKLLVLAEVIRQAE -AGQFALDDPLPMISEDQSGGSGILKDLSPATLTIRDHATLMIALSDNTSTMALVRLA-GR -ARIEQAGQEWGMTATTLP-----IDRAPDGDARDYSTPRDIVHLLQLIATDALVSPAASA -TVRDILVTQQY-HDQIGRYLPYNIVVRSKSGFMTDSVRVDAGIIEISGVPRYVLCLMTEH -HP--------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Kocuria rosea TaxID=1275 RepID=A0A543P3Y4_KOCRO ------------------------------------------------------------- -----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSAA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS--------------------- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6XRI2_9BACT ---DLVKRLNELCDAADFQASWYLKDLATGATA-DRLGDVPVPSASTRKISIMMAALAAVH -AGKLALDQKVTIDARYQDNDSGTFQHLTPGFITLRDAMVMMIIVSDNTCTGTVVELV-GL -ENVQRYTESVGLTGTVHRYGIPKVGPDNSLERVTTTTPNDQGLLLELILKGTQCTPALCR -LGLDILSWQRL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKAARPLCVLTAYTVR -VPEAL------------------ ->[subseq from] serine hydrolase n=1 Tax=Saccharothrix sp. NRRL B-16314 TaxID=1463825 RepID=UPI000526923C ----AAAKVRALFADAGVTGRLHAVDLDHDREV-SVGADDPVVLASVFKVPLVVALHHS-- ---GLDLTRRVTLDHDRSTGPTGVGGMLDPVTMSLRDLAYLALTVSDNAAADALVDLI-GL -DEVDRTVRELHLGRTVVVHRARDFARALDPAQTNRGTPRDLTTLLRHVWQHD-----QCA -PIRRIMALQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS -ASFTLPAADAVVGTAARLAVEH- ->[subseq from] Beta-lactamase n=1 Tax=Microgenomates group bacterium GW2011_GWA1_48_10 TaxID=1618496 RepID=A0A0G1UCF5_9BACT -----ASAVEQALKQSQGKYYVYVKNLKSGETY-SLNDHTLLPAGSLYKAWLAVETLDLIR -QGKIEEDEVLSAKVADLNAWAGLSAEELTEGFTVREAVQRMIAVSHNYAAYLLTRKV-GE -TSVRTMLRKHGLTESSYKR--PPL-----------VTAFDMGLFFEKVYDDEFFSGESAT -ELKDIFAANEL-NLGLPKYLPKTVRVEHKTGELGR-YKHDCGIVYSSGGN-YVICAMSES -GDP--LGAQERIARISKNVYDYf ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. CNB394 TaxID=1169151 RepID=UPI00037FF65C -------DLDAHLDKVPGTVSAYVGRPGARQAW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLGLDAPVPVRNSSALPGAPRFWDRVGGEVPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADSDDACRLIAHVSERV---- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Synergistetes bacterium HGW-Synergistetes-2 TaxID=2013843 RepID=A0A2N1QM40_9BACT -------AVRRETEKFPGTAGVVVSSLADGEGL-RHNADRVFSSASLIKLGVLYTLFVKQS -SGEIDLGECCEFSSLTAVEGGLLHRTRSGARLRLDDLALLMVSVSDNTAANMLIERL-GM -DAVNAEFKAMGLSGTVLGRKMLDFKAK-KEGRDNFTTAGDMALLLETLHSGERLPQETKN -RMMEILSAQKL-NTKLPGLIP--------------------------------------- ------------------------ ->[subseq from] hypothetical protein n=1 Tax=Kallotenue sp. CFH 73958 TaxID=2592335 RepID=UPI00128DA062 ---SLKTRLRQVALVHPGIQGVVVFEPSSARIV-ALNEDRPFMSASLAKLPVMLSLYKAAA -RGELSLEEEISILTSDVQGGSGVLHSYPAGYMTLRECASYMIKESDNTAWMMLERRL-GK -ARIVAELEALGAASTDYLA--------------YTTTPEDVLLMPGAVADPAYTSPELSR -EMLALMTDTAY-EDRLPQPLPEDVRVAHKMGSYGD-TFSDAGIVFPEDSDAYYIVVISDG -ATE--GVAHPAIRSMS------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Curtissbacteria bacterium RIFCSPLOWO2_01_FULL_42_50 TaxID=1797730 RepID=A0A1F5H1T5_9BACT ----LKETVENVLIGTKGTYGVAIKNLKTGETY-YLNEHRIFESGSLYKIWVLATAFDQIK -NGTLKQDEVLSQDISVLNEDAGSAEITDGKILSVKNAIEQMIVTSHNYASLLLSERI-KL -SAVSAFLEKYNFDESTISEP--------P-----KTTPYDIALFFEKLYKGELANNENTE -EMLTIFKRQQL-NEGMPKYLPQNVKIAHKTGEIGW-AKHDAGIVFSDSGD-YIIVIMSES -DSP--RQAQENIALVSRAIYDYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID69 TaxID=2690323 RepID=A0A6B1N687_9ACTN -----EDQVRAIFERAGCTGTLLVQPLDEEREF-GLGADQLVVPASVMKVLVALAAETWFA -EGRLDPRERVVLGAAGRTPGPVGLSLLEDDVLSWRDMVVLMLTISDNPCTDALMNRL-GV -GTLNATAARLGLRNTVVRSDVRTLLDALAPGAGTRTTARDMVRLLRLLWSGQAGPAEACA -RVRAVMARQLT-RHRIASGFRTPVRVAAKSGGLAGIVRNEVGVVSYPDGRRYAAAVFTRS -RTADEAAINAAIGAATAHAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinocrispum wychmicini TaxID=1213861 RepID=A0A4R2JL68_9PSEU ---EVTEEITRRAEEVGVRVWLHATDIDGSRRI-GIDGAQPVVAASVFKVPVAVELARQAA -AGEIDLGERVTYVPGTGTMPYGLATYRHEVTISWHDLAILMIGISDNVATDLVVGKV-GL -PAVAELLARLGFTHTAVPHDCEGLFQILDPAQTCRTSAEEITRLLAMVWRDQAAPEQACA -DVRNWLGLQVW-PHRLRSGFHDGIRVSGKTGTLPM-VRNEAGVVEYPDGGRYAVGVFTQA -YDMQAPERDNFIGFAAARA---- ->[subseq from] Beta-lactamase class A n=1 Tax=Saccharothrix saharensis TaxID=571190 RepID=A0A543JKQ2_9PSEU -----AARVRAAFADAGVTGHLHAVDLDDPTRDlSVGADDPVVLASVFKIPLLVALHHSAH -----DLTRRITLDRDRSTGPTGIGGMLDPVTMSLRDLAYLAVTVSDNAAADALVDLI-GL -DAVNDTLDGLHLRHTLVVHRARDFMRALDPDHTNRGTARDLTTLLRHVWRHD-----DCA -PIRHAMARQVW-PHRLASGFPDDVRVAGKTGTLPT-VRNEIGVVEYPDGGRYAVAVFTRS -ASFTLPKADAVIGTAARLAVEH- ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus kochii TaxID=859143 RepID=A0A248TGQ6_9BACI ----------------------AAVHIETDEGIlSVNSHQVFSSASLIKVPILLTALREVE -KGRLHLEEEVKGG--LSVGGAGVLSALSPNPFTWKDILTLMMIVSDNSATNWIIDRL-EM -ETINRLIKSLNLEQTCLNRKMMDFQ-AIERGVNNLTSAYDMVQLLRVMKDKGRWIKDSYM -LMESIMAKQQF--TLLTAELEPNISYGSKSGSLQ-GVQHDCAYFCHENK--YVLAAVLTA -NLPNQMIGKQLISEIGMAI---- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora chaiyaphumensis TaxID=307119 RepID=A0A1C4YM09_9ACTN -------DLDAHLDKVPGTVSAYVGRLGAPPTW-TRHADATHYAASTMKVAVLVALHRAAE -AGRLDLDAPVPVRNSSALPGTPRFWARVGGEAPLRWLAERMIVRSSNLATNLCIGQV-GL -PALTEAWTLAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGGLALGALASPAGCA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GIRHGAGVVFPEDAPPYAVVVCTTT -DLADEDDACRLIAHVSAAVWA-- ->[subseq from] Serine hydrolase n=1 Tax=Amycolatopsis sp. BJA-103 TaxID=1911175 RepID=A0A2N8MT79_9PSEU -----IATINARAKEVGVRVRLHAAEVDGTRRI-GVDEHAPVVTASVFKVPIALELARQAA -DGGLDLGERISVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLIVARV-GK -EETEKTLRRLGFEHTTVPQDCAEVLGALQPAHTCATTAEEITRLLGLIWRDEAAPPAACA -DVRRWLDLQVW-PHRLRSGFPDGIRVSGKTGTLPS-VRNEVGVVEYPDGGRYAVGIFTDA -VDSRVPERDSFIGFAAAQA---- ->[subseq from] serine hydrolase n=1 Tax=Bifidobacterium crudilactis TaxID=327277 RepID=UPI00068E20F0 ------------------------------------------------------------- ---------------------------HLNEAQSIDELLTQMITVSSNQAANDLISQLGGF -KLVNDIALKYGFTQTSLNDLLYDSGT--HDANRKTTSSQDCGRFMTAVYDGSLVSDDASQ -RMLSLLLAQTR-RSKIPAGLPDGTHVANKTGEIP-GTENDAALVYTTSGA-YVITVLTQD -IP-DSSNAQSGIREISRMTWE-- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. endophyte_N2 TaxID=2153485 RepID=UPI000FFE9E0D ------DKVRAIFERAGCTGTLLVQPLDSEGEF-GLDPDQLAVPASVVKVLVALAAETWFA -EGRLDPRERVVLGAAERTPGTVGVSLFEDEVLSLRDMVVLMLTVSDNPCTDALMNRL-GV -DTLNATAARLGLRNTVVRSDLRTLLDALTPGAGTGTTARDMVRLLRLLWSGQAGPAAACA -RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS -RPADDAAINAAIGAATAHAV--- ->[subseq from] hypothetical protein n=1 Tax=Caulobacter sp. OV484 TaxID=1500308 RepID=UPI0006921ADF --kRLQGRIEAIAARAPATLGVAVEDLTTRQLW-TFNGDQAFPLGPAARVPILAAVMAEAA -AGRLPPGELIAVRDVDLSPPSAVADAWPGRRWSVADLETLAL-HGDTTALDLLTKRIGGP -GAVNGWLDVQRIEGVSVDRYRRQIATARQGDARDTATPMAMARLLEAFAFRELGLAPDFD -GLLGH------DPGYLALALPKGARLAQAAGSAPTLGSQALAVVELKDGRRIAFVIFLTS -SAADAAKREALITDVGRAVLEEf ->[subseq from] Beta-lactamase n=3 Tax=Blautia TaxID=572511 RepID=A0A173TKY4_9FIRM ------------------------------------------------------------- ----------------------------------LNHLLELMITVSDNEAYNELMRRLGGC -QRVNQYLEREGYENTEVHHTLHPSSSASLGDGSNLTSVKDCGKLLERIYYGDCVSETASV -KMLKWLCRQQT-DWKIPAGIPKGIQIANKTGETDT-CQHDIAIVYAPSTT-YLLCVMSCE -LL-SENEGISGIQQLSAQVYEYf ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces rochei TaxID=1928 RepID=A0A510DF48_STRRO ----------EIFERAGCTGTLLVQPLDSEGEF-GLDADQLVVPASVVKVLVALAAETWFA -EGRLDPRERMVLGAARRTPGSVGVSLFEDEVLSLRDMVVLMLTISDNPCTDALMNRL-GV -DTLNATAARLGLRNTVVRSDLRTMLDALTPGAGTGTTARDMVRLLRLLWSGQAGPAAACA -RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS -RPADDAAINAAIGAATAHAV--- ->[subseq from] Beta-lactamase class A n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=A0A1D8C503_9PSEU ------DEITDTFAAIGVTGRLHALSLTTDREV-GADPDTPVVLASVVKVLIALEYARQAT -AGLLDPTSMVWVRDGDRLGGTGTAGFLDDVALSLRDLAGSMMSVSDNTAADLLLDRI-GL -AALRSAIGELGLGATTVLGAPRDILAAFDPAGTTSSTPRDMTRLLSLIWRDLAGSAAACA -EVRRLMSAQLN-WHRLAAGFDDEVLVAAKSGSLPP-IRNEIGVITYPDGRGYAVSVFVEL -TGGRRPDVDVAIGRAARLAVD-- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. NBRC 110037 TaxID=1621261 RepID=UPI0007DB30B0 -------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVARAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSACA -AMLDVLAAQEH-REDLAAGLPDGTRVAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSARVW--- ->[subseq from] Serine hydrolase n=1 Tax=Mumia sp. Z350 TaxID=2585211 RepID=A0A5Q6RXQ6_9ACTN ------------------------VATASGDVLaERNAGEAFYAASTIKVAPLVAAVRLLE -SGDLTLDTPLISRDTSQVPDAPDYGMAPAGEMPLREVLERMIIVSSNEATNMVIERV-GL -DAIASVLADAGAHDSRMSRQYGDQAAADAYGASNVVTAADLTALMGALVAGRLAGPESTR -FMVDLLARQE--DPLIAADVPDGVAWGSKSGSVE-AIRHDVAFVGTPGPDAVVMAVCTRG -YP--FEDANETIRALGGL----- ->[subseq from] Beta-lactamase class A-like protein n=2 Tax=candidate division WWE3 TaxID=422282 RepID=A0A0G1BP56_9BACT ----VETEFVELTKKLPGVYGLYIKDVGSGKEF-KYNDTTEFYSASLYKVPIAAAVLKEVE -AGKLKLDDTATYLPYDYASGTGVIGTYSHGILKISDILSELLKNSDNTAQNILLRTL-SY -KNVQDTFNA-----VVPDKNTSTFYRY------NLSTPGEISYVFEKLYFGDYLGTENKK -YLSDLMINTSF-EDRISAYLTDGLIFSHKIGSWPD-SWHDCGVVYTETKSELIVCLMSQR -A---------------------- ->[subseq from] Serine hydrolase n=2 Tax=Kocuria sp. 442 TaxID=2054280 RepID=A0A495A9K8_9MICC -------EVAEFLQSEDGAVSARVIDAPELPVF-SFHEEEVFPAASLYKLAVMMAFCREVD -HGVLEPSALVDLSPADRAQGPTGLAILEDTVISWRDLVRLMMSISDNAAAESVLRKV-GT -SRVHETLRLMGATRTEIRPTPPSGNGQYDPLSVSSTTASDLVTLLCAIWQDRAASAEQCA -FMRQVLSQQAWGHRFAEAFSYPGVTVAAKTGSFGS-LSHEAGVVSHPGEKSIAVAVLTRS -VRRQIPLSNKVVGQIARHCVRNy ->[subseq from] serine hydrolase n=1 Tax=Brachybacterium paraconglomeratum TaxID=173362 RepID=UPI00026C6E82 ---------------TEVRLAHCLLD-ADGAVLsASRADDPFYAASTIKLHVLLAVLRAAE -QGELDLDAELPATCTFTGAGEEFTPTHPEPGIALRDLATRMIDRSSNEATDQLLELV-GL -DAVAAVVGELGLTATRVERLIGDAS-ALERGLTNETSAADLARTMHHLVAGPGLSGDSHE -LALAALHAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAFVEDPAGGLRFLAVMTAG -LTED-EADARITAL--------- ->[subseq from] Peptidoglycan-binding protein n=1 Tax=Moorella sp. E306M TaxID=2572683 RepID=A0A4P6B9X0_9THEO ----LKKQIEEYLAGQPGTYGVFFKDLISGQSF-GINADTRLPAASTVKLPTVLFINHLVA -QGNLDWQQKLTYNSADYQGGSGILQFSVKDGLTLRTLTTMAITTSDNIAYNMLRNFV-GK -GSIASFMRSLGGQTVFP-------------DGQNLSTARDMATYVQAALDFAKVNPDGRR -LLDD-MANGIY-NEGIPLMIPAGVTVAHKEGFIW-GSPADVGVVFG--SRPFIITVLSQG -VE-DPDKGFANIATITKMMYDY- ->[subseq from] Beta-lactamase n=1 Tax=Clostridia bacterium 62_21 TaxID=1635276 RepID=A0A101FPF4_9FIRM ---ALRREMLAFIKQQPAAFGVYFADINANAVF-GIDENKPFPAASTVKLPVVLYLNTLAA -EGKVDWQEKVAYQPSDFQDGCGILRHRAKKGFSLRTLATLAITLSDNVAYRMLLRRL-GL -QRVAHFMRSLGGRVVFPR-------------GQNVTTAADMGVYLWGLLQFTARYGRLGE -RLLDDLANTIY-HVGLPGELPKRALVAHKEGEIA-GVANDVGIVFG--ERPFILAVLTRG -WA-DTSAGFAAIARLARLAWD-- ->[subseq from] serine hydrolase n=1 Tax=Streptococcus hyovaginalis TaxID=149015 RepID=UPI000A02A0E7 -------------------------------------------SASAIKLFILAAAHAKAT -RGELNLASNYTVKSSDIVEASLSLSGKVGKTFKLSDIASYMIQTSDNSATNIMIRQLGGI -AAVNAEIRRMGYNETTLNRYMR-IPSQINAGLENYISVHEAGDLIKNIVNGTLRDVNGEA -SMKQNLNKNVH-NYWLTNQTRTIATVFDKPGNDKYGVENDVAVITKNGR-GYVVALLTQE -SGSDSLTFSNLFSRFGLAVA--- ->[subseq from] Serine hydrolase n=1 Tax=Actinobacteria bacterium HGW-Actinobacteria-2 TaxID=2013647 RepID=A0A2N3GI37_9ACTN ---------------------ISLYAL-DGSIA-ELNAGAHHYAASTIKVAVLAALLRARA -TGLLAWDDTSEVHARDLAAQDPATWASLGSPVAWSVLAERMITVSSNIATDLIVERI-GI -TAVQDFLVEADLADLQFQRLIGDTAAQ-RAGHTNTVTADGLARLLVGLATDRWLPTSDSS -TAVEILSRQEY-RDGIGAGLPSGTWLASKSGWVP-GVRHDVALVRPPSAAPYALAICTTS -PVPD-AEAVALIAELSRITYQEw ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Streptomyces philanthi TaxID=371608 RepID=A0A367FC91_9ACTN ---------------------FLVRDLHTGDEV-GIEPDTELPVASLVKLPLAIATLERVR -RGELEGDRALEVSPGRITRPTGLTRFRHPARIAVDDLLYLATSLSDNTAADALFGLT-PP -ARVDALLEELGLTGIAVRHTMDELTDQLDVTRANTGTARAFTDLLQAVWTPSAVHPEVTA -RLRTLMGDNVMRHRLAPDFSSDSSSWSSKTGTLLN-LRHEVGVVQHADGAVYAVAALTES -RVATQPGAEALMAQVARELRD-- ->[subseq from] Uncharacterized protein n=1 Tax=Dehalococcoidia bacterium TaxID=2026734 RepID=A0A2E1ZCC7_9CHLR ---ALRSNVLEVIDEFSGTASVSANNLTTGDVL-DINEKEVLPALSAIKIGIMAELFFQIE -EGKYNLLDRVTINGSDLRGGTGVFREMETPLVTVKDLCMMMIVVSDNSCTWKLSSML-GV -DSINQRMRSLDMNEYSLNHDLPTAFDDMQGDAYSECSARDFTNLVTLIAKGELVSKTSSD -AMLDIMGRCQH-IEWLGRYLPPKVKLYNKLGAYLH-ARCDTGLIKSENSN-YVITVFASY -SKDEPHEGSRLIGKVSKVVYDAw ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO1212t TaxID=2650565 RepID=UPI00124BC5D7 -------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEAALRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGVDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPHDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Granulicella pectinivorans TaxID=474950 RepID=A0A1I6M3U7_9BACT ---VLKEQLAVAAVAHRGKVALFATQLNTGRTV-ALDPDVPVQTASVIKLTILFEAMEQVK -AGKAKWDEKIVLAPGDGVGGSGILHFFDTPLLTLKDVLTMMVIVSDNTATNLAIDRL-GI -DAINGRIAWMGLKDTHLYKRIGKPATDQPKFGLGKTTAREMATVMERIGRGEAAGAEDCS -VALE-MLRNQFYRETIPRYLEKGSGIASKTGSLD-AVRADVAIVAGKSG-PMILSIFTYG -NVDHDNEGELTIAKLAKMIVTAw ->[subseq from] serine hydrolase n=1 Tax=Syntrophaceticus schinkii TaxID=499207 RepID=UPI000A079C7A --qPLQEEVAKFTATLPGTYGIYLKDLASGEEF-GINEKTPIPPASTIKLPVVLYLYEQVA -AGKLDWRDRVSYNKNDYQGGAGDLQYVARHGYSLRCLATISITLSDNVAHNMLVRHL-GY -DNVMAFIKKLGPDTTRPF------GSA-------STTAKDMGAFVEEAYRFAERNPGQGG -RFLNDLAHTVY-HVGLPGELPPELVIPHKEGSII-GVATDAGIVFS--KRPYILVILSEG -IT-DEDTGFKNIAKISRIIYDH- ->[subseq from] serine hydrolase n=1 Tax=Sciscionella marina TaxID=508770 RepID=UPI0003793372 -----EDEIIARAEQVGLRVRMHARAIDGTGSF-GIGADEPVVTASVLKVPLAVELADQAE -REHCDLAEQITVPAGPKVPPYGLATFRHPVTLSLDALATLMIGISDNVATDLVFAKI-GK -PAVRALLDRLGLAGTVIEQDCAELLGALDPAQTCRSTAAEMTALLGMIWRDEAAGPGACA -DVRRWLGLQVW-PHRLRSGFHDEVRISGKTGTLPT-IRNEVGVVEYADGGRFAVAVFTEA -VDSQAPERDAFIGFAAARA---- ->[subseq from] Uncharacterized protein (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V7TST6_9BACT ----------------------------------------------------------QVE -EGRVDLGEV-TRPPMPRVRGGGVLQEVGDKVLTWRDLAVLMMGWSDNAATNVLIDRI-GM -DAVNRRLDSLGLRATRLRRHMMDLDAARRG-DENVSSPAEMRQLIEAMHAGHGLSGDRAR -DMMAVAAVPK--DSPFRVPLPESLVVADKPGSLE-AVRCVTAVVDLPGR-PYAVSIMTTY -LRRD-ADGEAAIREISAALYETf ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora inaquosa TaxID=2203716 RepID=A0A3N9X2Y3_9ACTN -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHPNAAHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVVNDDSAQGAPRFWDRVGGSASLRWLADRMIVRSSNLATNLVLGHV-GL -PAVAEVWALAGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGKLAAPAACA -AMLDVLLAQEH-REDLAAGLPDGTRIAHKNGWVN-GVRHGAGVVLPDDAPPYLIAVCTTT -DLADEDDACLLLAHISAQVW--- ->[subseq from] Beta-lactamase n=1 Tax=Brachybacterium sp. SW0106-09 TaxID=1704590 RepID=A0A0M8KPR1_9MICO ---------------TEVRLAHCLLD-ADGAVLsASRADEPFYAASTIKLHLLLAVLRAAE -QGRLDLDAELPATRTFTGAGEEFTHPEPGTAIALRDLATRMIDRSSNEATDQLLELV-GL -DAIAVVVGELGLGATRVERLIGDAA-ALERGLTNETSAADLARTMHHLVAGPGLSGDSHE -LALAALCAQTI--PIIATVLRDGVRWGSKSGWVD-GYRHDVAYVEDPAGGRRILAVMTAG -LAED-EADARITAL--------- ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium TaxID=1883427 RepID=A0A2N5KM43_9ACTN ----LRVDLEGAAGRHAGRYGVVAFDPDSGSGV-SLGGEQVFTAASVGKLPTLLALYRAAA -RGELDLDDKISILHEDYQGGTGVLHNFAPGTITLRECAYYLVNKSDNTAWAMLDRRL-GV -GTIQAEMAAIGAAGTDYG--------------MGTTTPEDVFLMLRKISDPSFTDGKLSG -EMISAMTDTAF-EDRIPASLPPDVRVAHKIGSYED-SYGDAGIVFYKDRRRYFIVVLSGG -TGE--GSARAAMQEISLTTYRH- ->[subseq from] serine hydrolase n=1 Tax=Brevibacterium epidermidis TaxID=1698 RepID=UPI000BF785B0 ---------GAELESAGLRARIIARDLGSNAEV-ALSPDGALPLASLVKVPIALAVLNRIK -AGELAADEQIRVDPAVNSTASPIGAARFRHPIAVEDLLTLAVCFSDNTAADALLDLV-PA -REVQRDLDELGLRGIDVRHRLDALVSQLDVSRANSGTARGLMDLLSELWRPGRVDPGSAA -RLRDLMSGNVVRHRIAPDLMSDSAQWSSKTGTLLH-LRHEIGVVDHADGQSIAVVVLSES -SIAVQPAAEAALGAAARALH--- ->[subseq from] serine hydrolase n=1 Tax=Prauserella endophytica TaxID=1592324 RepID=UPI0010BE8B01 -----AESIAEHWREVGATGHLLARNLDTGEHL-GFDVDTPVPLASVAKVPLALVVLDGIA -EGDLDPALAITIDPATKSLPSGVAAFRYPATLAVGDLLHLTLTVSDNASADALFDLV-GV -EHVDRRLRDWGCTGIRIRHRMHRMYETLDPAHANVGSATALVELLQRCWLDEVSRPDATA -ELRRLMALQVF-NQRLSSDLRADVRVSGKTGTFLH-LRHEIGVVTAESGDRVAIAALTRS -ARRAAHDIDLAIGAAARSAF--- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces sp. SID11233 TaxID=2706029 RepID=A0A6B3EXU0_9ACTN -------DIEEYFEQVGCEGALCVKPLEGDAGF-GLHADELVVPASVFKVQVALEVETAFA -EGRLDPCERVTLSTADRTPGPVGISLFSDDALSWRDMVVLMLTISDNHTTDALIRRV-GV -GALNGAATRLGLTGTVIESDLQAMLDALDPSQGTRTTPRDMVDLLRLIWTDQAGPAAACE -RVRAVMARQLT-RHRIASGFRLPVRVAAKSGSLVGVIRNEIGVISCPDGRRYAAAVFTRS -RPGSDAAISRAIGTVAA------ ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woesebacteria TaxID=1752722 RepID=A0A1F8CN41_9BACT --kKISEEFKNITKNLSGVYGLYVIRLNGEGAY-GIFDKEKFEAASLVKLPVLATLYKEAE -AGNIDLDTKYSLKNSDKITGSGSLSGKPAGTLTYRDLARFMGKQSDNTAYGIIKRIL-GD -AKINKEISDLGMTNTSLSD--------------HSTSPYDTGIFFEKLYKNQIVKEKYKN -EILDYLTDTIY-ENWLVAGIPEEIRVAHKYGRELH-VVNDAGVVFTK--EPFILVIMTKG -VV--EREADEFFPKLTKVIYD-- ->[subseq from] Beta-lactamase n=1 Tax=Verrucosispora maris (strain AB-18-032) TaxID=263358 RepID=F4FGJ5_VERMA ------------LDEVPGTISVYAGRLDAPPTW-TRHTEVTHYAASTMKLAVLAAVHHTAE -TDGPDLDTPVEVTNRFTSARAGAAWNRLGQRVPLRWLAERMIVRSSNLATNLLIEQV-GL -PAVAEIWARVGARHSVTRRGIEDFAAR-EAGISNLVTAADLAALLDAVATGPIASPAGCA -AMLDVLCEQQI-RQDIAEGLPAGTRLAHKNGWVR-GVRHGAAVVFPDDAAPYLLVVCTTT -PLDDDADARELVADISAQVW--- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Flammeovirgaceae bacterium TaxID=2026740 RepID=A0A2E2TRK6_9BACT ---------------------------------------------------VMIEIYHRAS -QGQLALTDSILVKNKSIVDYSTYEYTQIGKQMTLFDLMNQMIISSSNLATNILIDEV-GA -KNVNASMQRLGAYNTEVLRGVEDQK-AYDLGLNNMTTAKDLMTIFKSIALPLGETTQDQI -AMIDVLKAQEF-NDIIPRFLPGDVQVAHKTGSIT-GLHHDAGIIYLPNGETYVLVLLSKN -LK-NFDQGTLTLAKISQLFYEH- ->[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI0003777469 ------------LDRVPGTVSAYLARLDTAPTW-IRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFESAQPGAAWDRLGGTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG -DDPDHSPDEDACQLIADISAR-- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535WLD3_9CHLR -----GSAVEKIVATSGAGIAVALIELGDPEAW-SLAGSQQFEAASTYKLPLLMWMAQLVA -AGQLDVAGEVCYLDSDWEDG-WFTDYTTGDCFTRQELAARVGLYSDNTAAHMLVRDLGGS -DSLNAFARAYGATGSMFYD-------------VNTTTAADLAALWEAEVRGEIGGSAAQA -WLYPLLSHTKF-ETGVSAGVPSSVTVVHKTGEVD-GVVHDAALVTSGPGGPYILVVMTDN -LGGD--AAFKAVAEVSAAVWQY- ->[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00037A1216 ------------LDRVPGTVSAYLARLDAAAPTwIRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-RDDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG -DDPDHSPDEDACQLIADISAR-- ->[subseq from] serine hydrolase n=1 Tax=Kocuria TaxID=57493 RepID=UPI00119D5A0E ---ELHDDVATMLHAADMTGAVSVRVIGSDRSF-NYRAGVRFPMASLYKLVVMAAFCQAVD -DGLIDPAAPVELVPETRVPGPTGLSICLDPVMSWRDLVRLMMTISDNTAGNAVLCAV-GR -DRVAHTLRRLGLLQTDIRPYLPATDLEYDPLLVSSTTTSDLVDLLSFIWEDHAATPSQCS -FMRHVLGQQAWGHRFAEVFTYPGVQIAAKTGSLA-ALSHEAGVISHPDEPPIAVAVLTQS -ARRTIPLSNTVVGQIARHCVRSy ->[subseq from] serine hydrolase n=1 Tax=Saccharothrix variisporea TaxID=543527 RepID=UPI000EB2D221 -----------------VTGRLHAVDLADPRQV-AVGADEPVVLASVFKLPLLVALYRS-- ---GIDLTRRVTLDPGDRSTPTGIGGLLDPVTMSLRDLAFLAITVSDNAAADALVDVV-GL -DEVNRVLRDLGLTRTAVVHRARDFMRALDPTRTNRGTAREMTSLLTHVFAEDVYEPIRRA -M-----SLQV-WPHRLASGFPDDVRVAGKTGTLPT-VRNEVGVVSYPDGGRYAVAVFTRS -ASFTLPAADAVIGTAARLAVEH- ->[subseq from] Serine hydrolase n=1 Tax=Dermacoccaceae bacterium C5-26 TaxID=1660198 RepID=A0A563DXJ5_9MICO -----------------------VLD-GAGSVLaQRAPDREFYAASTIKLAVLIAAMRAVD -AGRLALDQELTATHTFRSAGSEFGEGMPAEGISLHDVLWRMVAVSSNEATNMVVDLV-GL -DAVAEALAHCGARNSVMQRPIGDVEGR-SAGLTNRVTAGDLAALMRAVITGAAASPASTE -RMVSILEAQQI--PYLGKGLPTGTRFGSKSGWVD-AIQHDVAFVAPSGDETYVIAVCTRG -YE--EADATELLAGVSRLAWD-- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rhizophila TaxID=72000 RepID=UPI0011A476A1 ---QLGREVAEILQSEDMTGAVSAIDAPELPVF-SFHEEEVFPAASLYKLAVMMAFCREVD -HGVLEPSALVDLSPADRAQGPTGLAILEDMVISWRDLVRLMMSISDNAAAEAVLRKV-GT -SRVHETLRLMGATRTEIRPTPPSGNGEYDPLSVSSTTASDLVTLLCAIWQDRAASAEQCA -FMRRVLSQQAWGHRFAEAFSYPGVTVAAKTGSFGS-LSHEAGVISHPGEKSIAVAVLTRS -VRRQIPLSNKVVGQIARHCVRNy ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Acidobacteria bacterium TaxID=1978231 RepID=A0A2V8HBI2_9BACT ----LAARIDALIKPTGADVAVVFGRVDGAASL-AIGADEPFHAASTMKVPVMIELFREAD -AGTLSLDEPLPVRNESIVDGSVYQYKAIGTTMTLGQLCDAMITVSSNFAANLLIERL-GV -QNIRATVAKLGAGGMNVLRGVEDDK-AYAKGLNNTTTARALFTLLQAIARGKAVSPR--- ------------------------------------------------------------- ------------------------ ->[subseq from] Serine hydrolase n=1 Tax=Verrucosispora sp. SN26_14.1 TaxID=2527879 RepID=A0A4Q9C8T6_9ACTN -------------DREPGTISVYAGRLDAPPTW-TRHAEVTHYAASTMKLAVLAALHRTAE -TGRLDLDTPVPVRNRFTSAYSCVRWDRLGRQVPLRWLAERMIVRSSNLATNLLLDHV-GR -PAVAEVWAAAGARHSVTARGIEDLAAR-DAGITNLVTAADLAALLRAVAVGAIASPTACA -AMRDVLCAQQV-RQDIAEGLPAGTRLAHKNGWVR-GVRHGAAVVFPTDAPPYLLVVCTTT -PLPADAHARRLVADISA------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. L2 TaxID=2162665 RepID=UPI001011F91B ------EAVAADWSALGVRGSFLARHIDTGEHL-GFDVDEVIPLASVVKVPLALVVLDRIA -RGELDAARPVTVDPASSVGPTGLAAFRHPATVAVGDLLLMMLSVSDNAAADALFDLV-PV -AEVDARLRDLGCEGLRVRHRMNHMYETLDPAHANTGSAAALVDLVERVWRDEVSRPEATA -ELRRLMGHQVF-TQRLAGELRADLRVSGKTGTFLH-LRHEVGVVEAASGDRVALAALTRA -DRRAAPDIDLAIAAAARRAFE-- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium varium TaxID=856 RepID=A0A414TUQ8_FUSVA -----EKRIREIINENSGVTGVIVRD-SFGKKI-MINEEVIFPSASIIKLFILMALNKD-- -----EYNKKIELKKEDKVGGCGILKVMEDGLLTIKDVAYLMICLSDNIATNILIDYI-GM -DKINESIKANGFRGTVLGRKMMDTEAR-KAGKDNFTTPEDVLKVLEILCGN------SD- --DLDMLRNQAY-NNKIPLYYPREVDFAHKTGELMY-TEHDAGRLFFDNGW-VDIVVLTKD -LE-ENEDGIKINSLIGKLIFDNy ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. M71_S20 TaxID=592872 RepID=A0A498A8D9_9ACTN -------ELDAHLDGVPGTVSAYVGRVGASPTW-TRHADATHYAASTMKAAVLVALHRAAE -AGTLDLDAPVPVRNESALPGAPRFWERLGGGAPLRWLAHRMIVRSSNLATNLVIGHV-GL -PAVARVWDLAGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT -DLADEDDACRLIARVSAAAWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Mycolicibacterium litorale TaxID=758802 RepID=A0A4V3H506_9MYCO -----EDQITAAFTDAGCRGWLRAERVGTGPVI-DISGDAPVVAASVYKVLVLIAAARAFD -AGRLDPHGTVRVVPGDCTPPTGISLFSDPVTLSWLDLARMMITLSDNAAADVLLAAV-EL -DTIDDVIEDLGLASTRVVGGTATLQRAFDPAYTTATSAADTNAMLTAIWTGRAASPESSQ -IMRTILSQQIW-PHRIRSAFPADVVVAGKTGTIGP-IRNEIAVVAFPEEIPVAVSVFTRA -ARSDLPIVDRAIGDTARIAV--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SM1 TaxID=402229 RepID=UPI000CD4BFD5 ------------------------------REV-AVGADDAVVIASIFKILLVLEFARQAV -AGQLDPTERVRVTSADRLGGWGTAGCLDDVELSLRDLAYFAMSVSDNSAADLLLDRV-GL -DTVRLLAKELGLHRTCLVGGPRDLLVVLDPRHTTSSTPREITRLLRLIWTDAAGPPEACA -LVRDLMSKQVF-RHRLVSGFPDGVAVAAKTGTLP-GLHMEAGVARYPDGECYAIAVFART -HDLTRVTVDAAIGRAA------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Eremiobacter sp. RRmetagenome_bin22 TaxID=2599629 RepID=A0A2W5XH40_9BACT --------------------YAYVCDLDRGRFG-QWRSDENVYPASVIKVPIMAEAYRQYD -AGVLSPDAHVVITESNQTTTDQPTPLVTGYLATARELVELMITLSDNVATNQLMDVL-RR -ERVTDYMHELGLPTFVLGRKLEPLIEDPEMTGRNRLPPAEIGRLLALIADDRIVGAAQQR -AILN---RCKE-NRKLGPGLAPGDRFMHKTGETSD-LSHDAGILVTPEGRRSVIVLYTEF -EPDTANAAEASNAA--------- ->[subseq from] Iron-regulated ABC transporter membrane component SufB (Fragment) n=1 Tax=Candidatus Amesbacteria bacterium GW2011_GWA2_47_11 TaxID=1618357 RepID=A0A0G1RCN4_9BACT --kEIADKLRKRVEGLSGEYAVGVYRLKTGENY-GFNQRVEMPAASIMKVPIMTAVLREAE -AGSLKLEDTYILKETDKRYGSGPLELLKAGTVTVERMLSVMGKNSDNTAPVVLARMI-GW -DKVTETLEKLGMTNSDFE--------------MNTTTAEDVVEMWAKLYEGGIVAQDHRE -MMWEWLTESIY-EERIPAGVPEWVHVVHKVGTDA-GVWADAGIVEC-------------- ------------------------ ->[subseq from] hypothetical protein n=1 Tax=Mycobacterium paragordonae TaxID=1389713 RepID=UPI0012E24259 ------------------------------------------------------------- -----------------------------------SQLCELMITMSSNLATNLLIKKL-GI -ENIRATVHLLGADGMNVLRGVED-NKAYDLGLNNTTTARALAILLTAIAEGKVVDPDASR -QMVEILKRQHI-NDGIPSGLDPTIPVAHKTGTLK-AIHHDAAIVYG--SQPFVLVILVRG -MA-DSKDSSALMADITRAFYR-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6VP27_9BACT ---DLVKRLNALCDGMPFQTSWYLKDLGSGASA-DRLGAVPVPSASTRKISILMAALAAVH -AGKLVLDQKVTIEARHQDNDSGTFQHLTPGFITLRDALVMMIIVSDNACTGLVVELV-GL -ENVQRYCDALGMKGTIHRYGMPKLAVGHSLDQVTVTTPNDQGMLLELILKATQCTSQLCK -LGLDILSWQKL-KTRLPSQLPLGTRVAHKTGTGPR-GYNDAGIVFKGDRPLFILTAYTEN -VPAAFAAAYQIIGRMARMAWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Streptomyces tsukubensis TaxID=83656 RepID=A0A5H2U075_9ACTN ---------ARSAAALPLVLAVAAIDVDDGRST-GVDDTAVLPVASAAKLLLLAEVARRLD -SGELDPAAAVAVTEDDVVHGTGLLVRLSRRDWTVEDLCWLTASVSDNTATNALLRLV-GP -ESTARLARSLSLGALTVHDRVRDVRGPDVPPVFATGTARALAGLVAHAARGSLVSPGASR -RLLSWMRSNTD-HTLAPALVSHDLLLANKTGTDP-GVRSDAGVFVGERRVAYAVVAHWDT -ALSTERAAVRAIRDVGRTLADY- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora palomenae TaxID=1461247 RepID=A0A561VFG3_9ACTN --------LDARLERVPGTVSAYVGRLGAEPTW-TRRPDATHYAASTMKIAVLLALHRAAE -AGELDLDAPIPVVNGSAQPGTPRFWARVGGTAPLRWLADRMITRSSNLATNIVLGRV-GL -PAVARAWALAGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLGGLITGALASPAACA -AMTDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYVIVVCTTT -DLADEDDACRLIAEISATVWA-- ->[subseq from] serine hydrolase n=1 Tax=Veillonella caviae TaxID=248316 RepID=UPI000F8DEAE8 ---SLEKQLQEVICNVTGTISYVVTRLSDGEEVaAFKETMIHVGASMVKTLILEYVFHLAY -EGQLDLHDTIALSRSPRVAGAGVLQELMGNHFTYLELCRLMMVISDNWATNLLIQAL-GM -EYINARAHQLGLEHFEINRFMMDTLAV-QEGRDNYITALDMAKLLHHIYNLRYT--LEGH -EMWSILGRQQF-RDILPFHWGEDVVFHHKTGSLEN-VEHDAGILETMNGD-FCFVMLMSH -VRND--VAK-------------- ->[subseq from] Beta-lactamase class A-like protein n=1 Tax=Streptomyces tsukubensis (strain DSM 42081 / NBRC 108919 / NRRL 18488 / 9993) TaxID=1114943 RepID=I2MTP7_STRT9 ----------RSAAALPLVLAVAAIDVDDGRST-GVDDTAVLPVASAAKLLLLAEVARRLD -SGELDPAAAVAVTEDDVVHGTGLLVRLSRRDWTVEDLCWLTASVSDNTATNALLRLV-GP -ESTARLARSLSLGALTVHDRVRDVRGPDVPPVFATGTARALAGLVAHAARGSLVSPGASR -RLLSWMRSNTD-HTLAPALVSHDLLLANKTGTDP-GVRSDAGVFVGERRVAYAVVAHWDT -ALSTERAAVRAIRDVGRTLADY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. AMSO12t TaxID=2650410 RepID=UPI00124B7F6A -------ELDAHLDGVPGTVSAYVGRVGAAPTW-TRHADATHYAASTMKAAVLVALHRAAE -AGALDLDAPVPVRNESALPGAPRFWERVGAEATLRWLAHRMIVRSSNLATNLVIGHV-GL -PAVARVWDLAGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT -DLEEDDDACRLIARVSAAAW--- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536DKI4_9CHLR --------------DPDGDYAVVMEDLKSGARV-AVNESQVFPSASLYKLGVAWMVLRQVD -AGTLHLDGPLDIAEPDTIEPEPDGGVAAGDRPTVREALADMLTISSNAAAHAFLRTL-GR -VDFNREMQRIGLSQTRIPEDVDADG--SDGDAQAVTSAADIARLLRLMATSQQLSAAARD -VLSECLASGAP-PDALRETLPAGIDVLEKTGNLDD-ASNVGALLQSARG-TVILVVLDHG -VD--PGDARGVIAQAGHVAYK-- ->[subseq from] Serine hydrolase n=1 Tax=bacterium TMED144 TaxID=1986778 RepID=A0A3S5JYJ1_9BACT ------KKIEILLNNFNGEVGFYFLHLEKGIDF-GINENKIFPSASLIKIPIMVQIFNXXE -NDNLNLDSLLFYDSSLINYDDSIARFKENETISINKLLTHMITFSDNHASLWLQNIAGGG -TKINEILNKYNFTKTKVNSRTLNREDQYLQYGWGQTTPKEMSKLMIEIKNGNIVSKKSSD -EMYRHLTRIYW-DDEALSQIPNHIQVASKQGAINK-SRSEVVLVNSLSGD-YVFCIITNN -QSDEENEGFVLIRKISRLLWNYy ->[subseq from] Uncharacterized protein n=1 Tax=Bacillus cereus HuA2-1 TaxID=1053201 RepID=J9B505_BACCE -----------------------------------------FMHPSTVKGLVTRVLLLQYP ---IKKLDEVITYTKDDLVEYSPSAEKHVDTGMTLREIAEATIRYSDNTAGNIL----DGP -KGFEKALKQIGNKVTMAACLEPALNEAIPRDIHDTSTAKTFATDLKAFTVRDALQTDKCK -IPTDWMRGNVT-E----------------------------------------------- ------------------------ ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora rhizosphaerae TaxID=568872 RepID=A0A1C6T684_9ACTN -------DLDAQLDKVPGTVSGYMARLGARPTW-TRLPDATHYAASTMKIAVLVALYRAAD -AGTLDLDTPIPVQNSSAQPGAPRFWDRVGGTAPLRWLAERMIVRSSNLATNIVLGQV-GL -PAVAEAWALGGARHSVTGRGIEDFAAR-EAGIDNLVTAADLAAVLGALAAGALASPASCA -AMLEVLFAQEH-REDLAAGLPEGTRIAHKNGWIR-GIRHGAGVVFPPDAPPYVIVVCTTT -ELADIDDACRLIADISARVWD-- ->[subseq from] serine hydrolase n=1 Tax=Amycolatopsis nigrescens TaxID=381445 RepID=UPI000380FEE3 ----VIETINDRAKEVGVRVRLHAAEIDGTRRL-GIDEHAPVVTASVFKVPVALELARQAA -EGGLDLGARITVPPGHPTPPYGLATFRHEITMSWYDLAILMIGISDNVATDLIVAHA-GK -EAVGETLRRLGLEHTTVVQDCREVLGALQPARTCATTAEETTRLLGLIWRDEAAPPTACA -DVRRWLELQVW-PHRLRSGFADGIRVSGKTGTLPS-VRNEVGVVEYPDGDRYAVGVFTDA -VDSRVPERDAFIGFAAAQAV--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. ALFpr18c TaxID=1458665 RepID=UPI00124B62BE -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHADATHYAASTMKVAVLAALHRAAE -SAALELDAHVPVVNEDSAQGAPRFWDRVGGTAPLRWLADRMIVRSSNLATNLLIGHV-GL -PALAEVWAVAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGRLASPAACA -AMLDVLLAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT -DLEVEDDACRLLAHISAQVW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora inyonensis TaxID=47866 RepID=A0A1C6S3F6_9ACTN ---------DARLAAVPGTVSAHVGRPGADPTW-THAAHTPHYAASTMKVAVLAALYRAAD -AGTLDPDTAVPVQNDFPSADGPRFWQRLDRTAPLRWLAERMIVRSSNLATNILLGHV-GF -PAVADVWTLAGARHSVTRRGIEDSAA-RAAGITNLVTAADLAALLGALAVGAVATPTSCA -TMLDVLCAQEF-REDLPAGLPAGVPIAHKNGWVT-GVRHGVGVVLPHDAPPYVLAVCTTT -DLT-DTDACRLLADVSARVWA-- ->[subseq from] serine hydrolase n=1 Tax=Salinispora tropica TaxID=168695 RepID=UPI00048EA4F2 ------------LDRVPGTVSAYLARLDAAAPTwIRHPATTHYAASTMKVAVLVALYRALE -AGRLASDTAVPVRNEFDSAQPGAAWDRLGDTAPLRWLAERMIVRSSNLATNLLLDQV-GL -PAVADVWARAGARHSVTGRGIEDFAA-RAGGITNLITAADLAALLRDLALGALATPESCT -AMLELLVAQEH-REDLAVGLPVGARIAHKNGWVR-GVRHSVGVVYPDDAPPYVLAVCTTG -DDPDHSPDEDACQLIADISAR-- ->[subseq from] serine hydrolase n=1 Tax=Halococcus sediminicola TaxID=1264579 RepID=UPI0006786E57 -----RDRVDAFGDRLDARFGAFFTTPGTFDVVhTVRPNERFTSASLIKLFVQYALYDRYD -GRLDALTEPYGLAAENRVAGTGLFHLLDDPDPTLEDLAMAMIGISDNAATNELIDHL-GR -EKINTVLNELGYADTRLGRKMMVTGGLPPGISENVTSPRDVASLVADTVHETTLSSVAYD -RLRVPLRHQHD-TSMVARYLPLGVDIEHKTGELTD-AVLDAGTLRIEDCDPLVFAVFLDE -LD-SPGEGTDVLASVGALVYD-- ->[subseq from] Uncharacterized protein n=1 Tax=Saccharomonospora glauca K62 TaxID=928724 RepID=I1D1I1_9PSEU ----VAESIAEHWREVGALGHLLARNLDTGEEL-GFDAETPVPLASVVKVPLALVVLDEIA -HGRLDAARPVTIEPARRSVPTGVSAFRHPATLAVGDLLHQTLSVSDNASGDALFDLV-GV -TTVDDRLREWGCSGIRVRHRLQRMYDTLDPAHGNVASAAALVELLHRIWLDRLAHPSATA -ELRRLMGLQVF-THRLSADLRDTVKVSGKTGSFLH-LRHEIGVVESESGDRVAIAALTRS -HRRAAHDIDLAIGAAARAAFE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora marina TaxID=307120 RepID=A0A1C4XTA8_9ACTN -------DLDAHLDKVPGTVSAYVGRPGARQAW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLGLDAPVPVRNSSALPGAPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADSDDACRLIAHVSEQVW--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Cryosericum septentrionale TaxID=2290913 RepID=A0A398DYY4_9BACT --------------------------------F-SQNSNLPFGAASIIKLPLLVCVAQLVE -LGELAWDRPIRLTVPA-PHGTGLLEHLDKSGWSVQDLCIMMMGVSDNMACNQLIEEI-GI -ERLNDVLQDLGYQATSIRRQMMDHE-TLARGIDNSVTAAEIADMLARLHAHRLVSNEASQ -RILDYLRMNQL-KDLIAWPLPGSAALAGKTGGMP-GSLLDAELVSVADGPTYSLCVFASG -FD-RAVQAKRLMVQVSERVYE-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Gottesmanbacteria bacterium RBG_13_45_10 TaxID=1798370 RepID=A0A1F5ZH49_9BACT ----LKHVIDKSLEGTTGVYGVVVINFQTGERY-AVNEHRVFVSASLYKLWVMATAFDEIQ -NGRLREDELLHQSIAVLNRISTRSAELTEGTLSVKNALEKMITISHNYAALLLSERV-KL -STVRRFLVNYGFTESALGE--P-----------TTTTAYDIALFFEKLYNGELADQEHTD -KMTDLLKRQML-NNKLAKYLPLDLPVAHKTGEIDL-YTHDAGITFGTNGD-YVIAVLSES -YFP--PGAAQRIADISKAVYDYf ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6TMP7_9BACT ---DLVTRMNALCDALPFQTSWYLKDLATGETA-NRLGDTPVPSASTRKISIMMAALKAVH -DGKLALDQKVTIDAKYQDNDSGTFQHLTPGFITFRDALVMMIIVSDNTCTGTVVDLV-GL -GEIQRFCESIGMSRTVHRFGIPRLGPDHSLDQVTTTTPSDQGLLLEMILRGVGSTPELCR -LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGSR-GFMDAGIVFKDDHPLFILTAYTEH -VPAALPD---------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. TR1341 TaxID=2601266 RepID=UPI00138AD7CD -------KVRAIFERAGCTGTLLIQPLDGEGEF-GLDPDQLVVPASVVKVLVALAAETWFA -EGRLDPRERVVLGAAERTPGTVGVSLFEDEVLSLRDMVVLMLTVSDNPCTDALMNRL-GV -DTLNATAARLGLRNTVVRSDLRTLLDALTPGAGTGTTARDMVRLLRLLWSGQAGPAAACA -RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS -RPADDAAINAAIGAATAHAV--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora globispora TaxID=1450148 RepID=A0A317KJL4_9ACTN --------LDAHLDTVPGTVSAYVGRLGAGPTW-TRLPDATHYAASTMKLAVLVALHRAAE -AGRLDLDAPIPVRNAD-SADAPRFWDRVGGTAPLRWLAERMIIRSSNLATNVVLGQV-GL -PAVAEAWRLGGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLAAVAEGALASPESCA -AMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAIVVCTTT -DLADDDDACRLVARISARVWE-- ->[subseq from] Peptidoglycan-binding LysM n=2 Tax=Clostridia TaxID=186801 RepID=A0A101EB56_9THEO ----LKQQIENYLAGQPGTYGVYFKDLISGRSF-GINADLPLPAASTVKLPAVLFINYLVD -RGNLDWQDKLTYRSDLHYQGSGILQFGVKDGYTLRTLTTLSITLSDNIAYNMLRHFV-GK -ETLAQFMRQLGGQTVFP------------N-GQNLSTARDMATYVQAALDFSQASPDGRR -LLDD-MANGIY-NEGIPAQIPVGITVAHKEGFIW-GSPGDVGVVFG--SRPFIVTVLSQG -VE-DPDQGFANIAAIAKMMYDY- ->[subseq from] Beta-lactamase class A n=1 Tax=Ureibacillus xyleni TaxID=614648 RepID=A0A285SXV6_9BACL --eNLSKEINQYIKKFSGSIAIEYYDLTTGETY-QNNATKAYVAASTIKLPLAMYIMELAD -QEKIDLNQKLTYKKHHYVGGSGVLLGKVGSKYTIKDLLRKSMVFSDNIAYSMLKEKV-GE -KNYVKYMKKLGATYSSRN----AL---------SNTSAHDLILYVQQLYKLGQ-TTENGN -ELNKYLQQTIY-NETIPAGVK-GVKVAHKVGMIPYQLSHDVGIVY--DESPYAIAVMTKG -FS--YEKSKKIIADISRIVNKH- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. WMMA1996 TaxID=2039878 RepID=UPI000BF61961 -------DLDAHLDKVPGTVSAYVGRPGARPTW-TRRADTTHYAASTMKVAVLVALHRAAE -AGRLDLDAPLPVRNSSALPGAPRFWERVGGAAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTVVVCTTT -DLADEDDACRLIAHVSARVWD-- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Curtissbacteria bacterium RIFCSPHIGHO2_02_FULL_42_15 TaxID=1797716 RepID=A0A1F5GCQ9_9BACT --------IVSNAQNQPGKWAIYIKDLKIQNTY-ELNSARVFGAASVYKLAVMYAAYDAIE -TSKLKKNDVLYADKTTLDQISGMQNQPPDQTYTVERALNLMITISDNYSALLLAERL-GW -ANMDKLMEQQGFAEINLVGA----NS-------PNITARATGTLLEKIYNKETVDEQSSQ -EMINLLLAQKV-NDRIPKYLPQDVKVAHKTGELET-IRNDAGIVYGKKGT--YIFVFLTD -TPQPLDATEQ------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Amycolatopsis xylanica TaxID=589385 RepID=A0A1H3H181_9PSEU ----------ARAEEVGVQVWLHAEEVDGPGRI-GIGESEPVVTASVFKVPIALELARQAA -AGELDIAEPVTVQPGHPTPPYGLATFQHEVTMSWADLAVLMIGISDNVATDLILAKI-GI -PKVAELLKTLDLPNTIITSDCADLLAALDPKQNRGTTAEEITKLLSLIWRDEAAQPQACA -DVRRWLGLQVW-PHRLRSGFPDDVKVSGKTGTLPL-VRNEVGVVEYPDGGRYAVGVFTRA -VDARVPERDAFIGFAAA------ ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. CT34 TaxID=1553907 RepID=UPI0005BB1E8C ------ETIADDWAALGVRGSFLARHLDTGEQL-GFAVDEPVPLASVVKVPLALVVLDRIA -TGELDAARPVTVDPATSSVPTGLAAFRHPATVAVGDLLHLMLSVSDNAAADALLDLV-PV -ADVDARLRAWGCSGIRMRHRLNRMFETLDPAHANLGTAAALVDLLQRVWQDDIGHPEATA -ELRRLMGRQVF-TQRLASELRADLRLYGKTGTFLH-LRHEIGVVEAAGGDRVAMAALTRS -DRRA------------------- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ285 TaxID=2035250 RepID=A0A4Y9VD68_9ACTN -------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSSALPGAPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -ELADEDDACRLIAHVSERVW--- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora terminaliae TaxID=1914461 RepID=UPI0012AED26C --------LDAHLDTVPGTVSAYVGRLGAPPTW-TRHADATHYAASTMKVAVLVALHRTAE -AGRLDLDAPVPVRNSSALPGTPRFWARVGGEAPLRWLAERMIVRSSNLATNLCIAHV-GL -PAVAEAWTLAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGGLARGALASPAGCA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT -DLEDEDDACRLIAHVSAAVWA-- ->[subseq from] Beta-lactamase n=1 Tax=Nocardioides sp. Root151 TaxID=1736475 RepID=A0A0Q7ZQ01_9ACTN ---EVAHEIRQAWSEAGLRGAFSARNLDTGEEL-GFEPDLPFPLASVSKVPLALVVLDLIA -CGELDAERQVTLDPKDRTPPTGISSFRHPTSVAVEDLVLLMLTVSDNAAADALFEIT-PP -AAVADRLAAWGCTGIQVRHPIRTLYDALDSGTATCGTSRGLVDLMDKVWNDRVSVPTATA -RLRELLGGQVN-GARLASGLSSDVRVHSKTGTFLN-LRHEAGTICSSAGDRIAVAALTAS -TVPSQPEAERAIALAGRAAFE-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sediminicola TaxID=946078 RepID=A0A1A9B8X6_9ACTN -------DLDAHLDKVPGTVSAYVGRPGARPTW-TRRADTTHYAASTMKVAVLVALHRAAE -AGRLDLDAPLPVRNSSALPGAPRFWERVGGAAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAA-RDAGIDNLVTAADLAALLGELALGTLASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTVVVCTTT -DLADEDDACRLIAHVSARVWD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ309 TaxID=2035247 RepID=A0A2N3Z1Y7_9ACTN ------------LDEVPGTVSAYVARVGAAPAW-TRHADTTHYAASTMKAAVLVALHRAAE -AGTLDLDAPVPVRNESALPGAPRFWERVGADGTLRWLAHRMIVRSSNLATNLVIDHV-GL -PAVARVWDLAGARHSVTGRGIEDFAAR-EAGVTNLVTAADLAALLGALAAGALASPAGCA -AMLDVLFAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAVVVCTTT -DLEEDDDACRLIARVSAAAW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Kitasatospora sp. SolWspMP-SS2h TaxID=1305729 RepID=A0A327TUH1_9ACTN ------------------------------REF-GFRADEPSVPASVVKVQVALEAETWFA -EGRLDPGERVTLSAADRTFGPTGTSLFEDDALSWRDMVVLMLTISDNHTTDVLLRRI-GV -DAVNATAERLGLTGTALESDLRAMLDALDPSRGTRTTPRDMAELLRLIWTDRAGPAAACA -RVRTLMGRQLT-RHRIASGFRPPVRVAAKSGGLLGVVRNEVGVISHPDGRRYAAAVFTRS -RPSDETAINAAIGTATAR----- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A536LK19_9CHLR ----LQAAIETALAGREGSYSVVVHNLANGRGA-SLNADKVYYAASLYKLEVLLEVFRQRD -AGQLDFGGLLTLEKKYIDLTLDALEILENDEVTVRDAVRAMTIVSDTPTAALLQDTV-GA -GRIDETLASLGLGSTQSANRELP------------TSARDMARLLTAIAAGEGVNAGSRN -EMLSLLEQEGY-RAGVIAGVPPDAAVAHKTGSYSD-ATHDVALVWGPKG-PYVIAVLTDR -SY-----DWDAIREVSRAVWDYf ->[subseq from] Beta-lactamase class A n=1 Tax=Plantactinospora sp. CNZ320 TaxID=2035246 RepID=A0A2N3S6Q0_9ACTN ------------LAAVPGTVSVYAGRLGRRPAY-TRLPDTPHYAASTMKVAVLAALHRAAE -AGEVELDAPVPVVNE-FDSASPGAWARVGGSAPLRWLAERMVVRSSNLATNLVIRHV-GL -PAVARVWADSGARHSHTRRGIEDFAA-RDAGLDNLVTAADLAGLLGGIARSRLASPGACA -AMLDVLLAQER-GEDLAAGLPPGTRIAHKDGWVR-GVRHGAGVVFPDDAPPYAVVVCTSA -PPDTEARARQLVTRVSALVW--- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rosea TaxID=1275 RepID=UPI000D644033 ----LAADLEELAAEVPGELGVVLLDPEGGEVV-ARNADRPFTSASLYKLFLAHAVLDRAD -RGALALSDVV-----------------PGLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVETFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSAA -LLLGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS--------------------- ->[subseq from] serine hydrolase n=1 Tax=Brevibacterium linens TaxID=1703 RepID=UPI00057C8B02 ---------GAELESAGLRARIIARDLGSNAEV-ALSPDGALPLASLVKVPIALAVLNRIK -AGELAADEQIRVDPAVNSTASPIGAARFRHPIAVEDLLTLAVCFSDNTAADALLDIV-PA -RDVQRDLEDMGLRGMDVRHRLDALESQLDVSRANSGTARSLMDLLAELWRPERVDPGVAA -RLRELMSGNVVRHRIAPDLMSDSAQWSSKTGTLLH-LRHEIGVVDHADGQSIAVVVLSES -SNAVQPAAEAALGAAARALH--- ->[subseq from] Beta-lactamase class A n=2 Tax=Ruminiclostridium cellobioparum TaxID=29355 RepID=S0FPH9_RUMCE ---ELKKIITDYTSKLSGRYGVTYIDLATGEMV-NVSDQVEYIAASTSKLPINMVLFKDIE -AGKVSLEDKLVYKEEDLEYGTGIIQNSPYGTYTVRETSKLAIRKSDNCGVNMIIRQV-GI -ENVRKYLTDLGGKVYY--------------GKTHRSCPYDMALVARDLYSHYLDNEAVYG -ELINNLENTDW-NDRISAKLT-GVKVAHKIGNQTK-TANDVGIVFG--KHPYVLSVMTED -VD--FGTACNNIAALSKKI---- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6YIM2_9BACT ---DLVKNLNELCERAEFEVSWYLKDLASGVAA-DRRGKVAVPSASTRKTSIMMAALAAVH -AGKLSLDQKVTIDKRFQDNDSGTFQHLTPGFISLRDAMVMMIIVSDNTCTAHVVDLV-GL -SNVQRYTESVGLTGTVHRYGIPKAAPDSSLDRVTTTTANDQGLLLELILKGTQCTTALCR -LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGHR-CYNDAGIIFKGDRPICILTAYTVD -VPDA------------------- ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Desulforudis sp. TaxID=2093368 RepID=A0A3A6MPH3_9FIRM --tRLQAELQAKLAKAPGEYGLCLIDLASRSRF-GINEEKIFHAASTVKIPINLYLAQKFA -NREIDPAEYLTYEAVHYEGGTGYLHTHSFGNYQIARLSRDSIVYSDNVATNIILSRL-GR -KQVKDFMRSLGAEAVEND--------------RNTTCPKDMALMMEALVLFADEHPAEGG -LLLEYLRTSVF-RDGIPAAALDTVPVANKIGFWASGTYNDVAYVEHPAR-PYVLAIYSKD -TP-GREAAFAHIRRLASVVYSY- ->[subseq from] serine hydrolase n=1 Tax=Actinopolymorpha alba TaxID=533267 RepID=UPI000382EC66 -----AESVAADWERVGARGHLLARNIDTGEEF-GFDADTLVPLASVIKVAIALAVLDRTA -AGTLDPAYQVTISPGTRSLPTGLGAFRYPATLAVGDLVHQMLTVSDNAAGDTLLDLV-GI -DEVNRSLRAWNCPGIRIRHRLHRYYEILDTAHANVGSATALVDLLQRVWLDQISQPSATA -ELRRIMALQVF-TQRLSSDLRDTVRVSGKTGTFLH-LRHEIGVVETDSDDRIVIAALTRS -TRRAAADIDLAIGAAARSAF--- ->[subseq from] serine hydrolase n=1 Tax=Nocardiopsis sp. FIRDI 009 TaxID=714197 RepID=UPI000E21D454 ---ALVRELRQELDEGGLRGSFLVRDLASGREV-GIEPDLEYPTSSVVKVPLAIAVLELVR -RGELDGAAPVEVRPEDVGVVGPFGLSRFRHPIAVEDLIYLSLCLSDNKATNLLFERV-PP -EEVARVLRTFGIGGVTVRHAIRELREQLDVTRTNTASARACVDLLAALWTPSRIPPEVAA -RVRELMGANMLRHRLAPDFTSDSTRWSSKTGTLLH-LRHEIGVVEHEDGQAFAVAALTES -RVVVQPEADALMARVARALRDH- ->[subseq from] Uncharacterized protein n=1 Tax=Brevibacterium linens TaxID=1703 RepID=A0A0B9A173_BRELN ---------GAELESAGLRARIIARDLGSNAEV-ALSPDGALPLASLVKVPIALAVLNRIK -AGELAADEQIRVDPAVNSTASPIGAARFRHPIAVEDLLTLAVCFSDNTAADALLDIV-PA -RDVQRDLEDMGLRGMDVRHRLDALESQLDVSRANSGTARSLMDLLAELWRPERVDPGVAA -RLRELMSGNVVRHRIAPDLMSDSAQWSSKTGTLLH-LRHEIGVVDHADGQSIAVVVLSES -SNAVQPAAEAALGAAARALH--- ->[subseq from] serine hydrolase n=1 Tax=Bifidobacterium goeldii TaxID=2306975 RepID=UPI000F7F1817 ------------------------------------------------------------- ------------------------------DTATIDADLTQMITVSSNDAANRLLAVIGGT -QGTAQAIATVTDTAQRYGFTTQELRAASGNTVENWTSSLDCGRFLMKAYNGELVSQNASK -RMTDLLLGQTR-RSKIPAGVPAGIQVANKTGELA-AVQNDVAIVYG--THPYVLAVMANN -VDGSA---VTRISSLSAAVYQAf ->[subseq from] Serine hydrolase n=1 Tax=Nocardiopsis sinuspersici TaxID=501010 RepID=A0A1V3C8I4_9ACTN -------------------VRVHAREIDGTGQV-GRLADEPVVLASVAKVLIALEFARQAS -TGLVDPTERVVVRRDDRLGGWGTADFADDVELSLRDCALLAMTISDNTAADLIVDRV-GV -EPVHLLAVELGLERTRFTGGPRALLHARDPSRTTSSTPADITRLLRLVWTDAAAPPKACA -FVRDLMARQLV-RTRIASGFGPDVRVSVKSGTLP-GLRMEAGVVEYPDGGRYAVAVCAVG -PDRTALEADMALGRAAREAVE-- ->[subseq from] hypothetical protein n=1 Tax=Faecalicoccus pleomorphus TaxID=1323 RepID=UPI00143113B7 ------------------------------------------------------------- -------------------------------------YLEAMIIHSDNTSYNILLEKLGGA -SKVTAFCKKLGLTRTEIHHGLEPGDGYFSDGQNNTTCPEDVGQFFEMLYHSEIVSDSSCK -DMLNLLKQCAD-DTGMVAGLSEDTECAHKSGWAD-AYYLDGGIIYTEHKD-YILVVFSDS -AYQTPA----------------- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces achromogenes TaxID=67255 RepID=UPI0004C87584 ----VAEAIAEDWAALGVRGSFLARNLDTGEQL-GFDTDEPVPLASVAKVPLALVVLDRIA -AGELDTARPVTVDPRTSSVPTGLAAFRHPATVAVGDLLLLMLSVSDNAAADALFDLV-PA -AQADARLRAWGCDGIRVRHRMNHLYETLDPAHANAGTAAALVGLLQRVWRDEIASPPATA -ELRRLMGHQVF-TQRLAGELRADLRWSGKTGTFLH-LRHEIGVVEADSGDRVAMAALTRA -TRRAAPDIDLAIGAA-------- ->[subseq from] Serine hydrolase (Fragment) n=1 Tax=Verrucomicrobiales bacterium TaxID=2026801 RepID=A0A3D3P151_9BACT ------------------------------------NVDEFSPAASMIKIPILASILDKVE -RGKIGYQDKLTYTKDRRFPGEDLLGSFANNQLTLKKLVFLMITTSDNTASLWCQELAGTG -TTINTWLKQKGFLHTRLNSRTPGRADARDRYGWGQTTPREMAQLLIRIRNRKLVSPAADE -EMARVMGRIYW-DGEALSSVPPSISTMSKQGAVN-ASRSEVVLVHAPHGD-YVFCLITKN -QKQHDNKGFELLRDISRILWEHf ->[subseq from] serine hydrolase n=1 Tax=Phycicoccus jejuensis TaxID=367299 RepID=UPI00068C4612 ---NLREALRADLADAGLRASLLARNLGTGREV-AIDADVLTPAASLAKLPLALAVLTRVD -DGRLDGGARIEVPPGQPHEATPGLGRLRHPAVAVEDLVGLALTVSDNAAADALLRLV-PP -AEVTADLDALGVAPMVVRHPFAELSDQLDVARTNVVTARSTADLLERVWTGRGLRPAVAE -RLREHLHGNALRHRLAPDLASDDARWASKTGSLLN-LRHEAGVVEHADGTLVVVVALSTS -SVSVQPAADASLGAAARAVHDH- ->[subseq from] Serine hydrolase n=1 Tax=Nonomuraea sp. 6K102 TaxID=2530382 RepID=A0A4R5E523_9ACTN ------RRLNALCDTQPYVTGWCLIGLPDGGVRaDRHGARAFPAASTRKVAVMMAALRAVH -RGELDLDARLSIDGRYRDRFTGLLQ-HLDPGLSLRDAVTLMIIQSDNLSTAHVLDLV-GL -DAVNDLCASAGLTGTRHRHLIPRLAPDHPVDASNVTTPGDQARLLELIARGSAAEPEANR -LLLDVLCHQQF-RDTLPALLPYGTKVAHKSGAGWR-DVSDGGVFFGDDGPRYVLAVYTDE -L---------------------- ->[subseq from] Serine hydrolase n=1 Tax=Chloroflexi bacterium TaxID=2026724 RepID=A0A535M9N2_9CHLR ----LAAQLSGVQSASGARIAVSLIELGNPQSW-SFHGDDPFVAASTYKLPLLMAEAEAIA -AGQEQPGDQLCYSAEDWEDG--WFQDYSAGAYSREDLASRIGQDSDNTAAHMLVRFLGGG -SALNAYAAGHGASESAFY-------------DPNTTTASDLARLMAAEATGAAGGASAQQ -WLYPLLTHTAF-EQGIPAGVPATVTVVHKTGELDS-VTNDVALVLGGADGPHVVAICVDG -PGSD--AGFSVIAQVASLIWE-- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A349VQ10_9FIRM ---ALQTKITDYLASQNGRYGVYYINMNNGETL-GVKETQPIVAASSIKIAYNTYLYEKAA -SGEISLDEKMKYNAAAYPQGTGNIQNSADGTYTVQEVSHRSITISDNCGTNMVLRRLGGE -DAVNNYLKTISAVDYRSKVEYTDYAGN-TQNGRRRTSAIDLAKYAEHLYKDYRGNETHYQ -PLIDDLCNTEY-NWGVPAGVPGTVKVAHKVGFNSYGANNDVAIVFGSE--DYVLCVMTES -GD--GQKAQDIIGEVSKMIYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Clostridiales bacterium TaxID=1898207 RepID=A0A359JKT7_9FIRM ---ALQTKITDYLASQNGRYGVYYINMNNGETL-GVKETQPIVAASSIKIAYNTYLYEKAA -SGEISLDEKMKYNAAAYPQGTGNIQNSADGTYTVQEVSHRSITISDNCGTNMVLRRLGGE -DAVNNYLKTISAVDYRSKVEYTDYAGN-TQNGRRRTSAIDLAKYAEHLYKDYRGNETHYQ -PLIDDLCNTEY-NWGVPAGVPGTVKVAHKVGFNSYGANNDVAIVFGSE--DYVLCVMTES -GD--GQKAQDIIGEVSKMIYEY- ->[subseq from] Uncharacterized protein n=1 Tax=Fusobacterium nucleatum CTI-6 TaxID=1316587 RepID=U7TNV0_FUSNU --tEWKKEIEKIISQVEGKVCINFYDLNKNDGF-SINGNEKVLSASMIKLLILAELMKKKS -ENKFSLSDTIMIANSMKTGGDGVLKELNAGHFTLKELATLMIIVSDNQATNILIDFL-GM -ENINLLGKELGLKESFLGRKMMDTEA-RKNGYDNYTCADDISLLFKLIYQEKLINKEASQ -LIKNM------------------------------------------------------- ------------------------ ->[subseq from] Carbepenem-hydrolyzing beta-lactamase KPC n=1 Tax=Klebsiella pneumoniae TaxID=573 RepID=A0A2P1BNC2_KLEPN -----AEPFAKLEQDFGGSIGVYAMDTGSGATV-SYRAEERFPLCSSFRAFLLPLCWLAAS -SRPACWT-HPSVTAK--CAGSVVTHKYLTTGMTVAELSAAAVQYSDNAAANLLLKELGGP -AGLTAFMRSIGDTTFRLDRWE--------------------------------------- ------------------------------------------------------------- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Micromonospora parva TaxID=1464048 RepID=UPI0004C0899C -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHANAAHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVVNDDSAQGAPRFWDRIGATASLRWLADRMIVRSSNLATNLVLGHV-GL -PAVAEVWALAGARTSVTGRGIEDFAA-RDAGITNTVTAADLAALLGALAIGALASPAACA -TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYVIAVCTTT -DLADEDDACLLLAHISAQV---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442) TaxID=644283 RepID=D9T565_MICAI -------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSFDSAGVPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGRLASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ299 TaxID=2035244 RepID=A0A2G6XSA0_9ACTN --------LDAHLDKVPGTVSAYVGRPDAPPTW-TRHPDAAHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVLNEDSAQGAPRFWDRLGGTASLRWLADRMIVRSSNLATNLVIGHV-GL -PAVAEVWAGTGARTSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGALASPAGCT -AMLDVLLAQEH-REDLAAGLPEGTRIAHKSGWVR-GVRHGAGLVLPDDAPPYLITVCTTT -TTEVEDDACRLLAHIS------- ->[subseq from] Class A beta-lactamase n=1 Tax=Veillonella sp. ICM51a TaxID=936591 RepID=X8H3D4_9FIRM ----LEIQLAALLDTLDATVSYMVTRLNEGEEA-TIVASSKHTGASMVKTLILEYVFHLAA -QEQLDLNDTIALSRSPRVEGAGALMELVGNHFSYLELCRLMMVLSDNWATNLLMQAL-GM -ENINARAEQLGLEHFEINRMMMDFTAA-KENRENYITAMDMAVLLHHIYEL--RHTIYGH -EMWNILGRQQF-RDILPFHWGEDVIFHHKTGSLDC-VEHDAGIIETMNGD-FCFVLLMSH -LDND--KAKQLGA---------- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora globispora TaxID=1450148 RepID=A0A3N9VG76_9ACTN --------LDAHLDTVPGTVSAYVGRLGAGPTW-TRLPDATHYAASTMKLAVLVALHRAAE -AGRLDLDAPIPVRNAD-SADAPRFWDRVGGTAPLRWLAERMIIRSSNLATNVVLGQV-GL -PAVAEAWRLGGARHSVTGRGIEDFAA-RDAGITNLVTAADLAALLAAVAEGPLASPESCA -AMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYAIVVCTTT -DLADDDDACRLVARISARVWE-- ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. SM24M-10 TaxID=1660349 RepID=A0A0J1EZD2_9MICC ---TLADDLEQLAVGVPGELGLVLLGPDGDELA-SRAADRPFTSASFYKLFVAHAVLERVD -RGELALDDPVP-----------------GSALTVGTALAAMISWSDNPSGAALGRWL-GW -AELEEFAHRHGFPATTFDPDTGDADRV-----AMTTTPADVAALLERLRRGELLSPASTA -LFRQLLEDQQL-DYALPSGFSPGTAFAHKTGLLED-VSHDAGLLTLDGRE-HVVVVMTD- ------------------------ ->[subseq from] Beta-lactamase n=3 Tax=Candidatus Gottesmanbacteria TaxID=1752720 RepID=A0A0G1IQ35_9BACT -----EEIVPKTLSGNEGTYGIVIKNLQTEETY-LSNEHHKFQSGSLYKLWVMATAFDQIK -NGLLKLEQEIPILNEKFRIATADAERIEGKILSVADALNQMITLSDNYAALLLSEKV-RL -SNVAKFLNTHGFSESKVGTDG-----SIP-----ITTPSDIAEFFTKLYEGTLIDKEYDK -KILDLLKQQKL-NNKIPKNLPENIAVAHKTGEFNS-FTHDGGIVYTPYGD-YIIVILSES -QD--PLNTEEAIADLSKAVYGHf ->[subseq from] Beta-lactamase n=2 Tax=Patescibacteria group TaxID=1783273 RepID=A0A0G1FTC2_9BACT -----EEIVPKTLSGNEGTYGIVIKNLQTEETY-LSNEHHKFQSGSLYKLWVMATAFDQIK -NGLLKLEQEIPILNEKFRIATADAERIEGKILSVADALNQMITLSDNYAALLLSEKV-RL -SNVAKFLNTHGFSESKVGTDG-----SIP-----ITTPSDIAEFFTKLYEGTLIDKEYDK -KILDLLKQQKL-NNKIPKNLPENIAVAHKTGEFNS-FTHDGGIVYTPYGD-YIIVILSES -QD--PLNTEEAIADLSKAVYGHf ->[subseq from] Peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 n=1 Tax=Ruminiclostridium papyrosolvens DSM 2782 TaxID=588581 RepID=F1TI99_9FIRM ----LKKIITDYTAGLSGKYGVTFIDLATGEMV-NVRDTDRYIAASTSKLPINVLLYKNIE -SGKVKLDDMLTYQKEDVEPGTGIIQKSAGTQYTVRETSKLAVTKSDNCGVNMIIRLL-DI -QNVRQYLVDLGGKVY--------------YDNHHRSCPYDMALVAQDLYKHYLKNEAVYG -ELINNLENTDW-HDRIDAQLT-GVKVAHKIGNQVK-TANDVGIVFAS--HPYVLSIMTDN -VD--------------------- ->[subseq from] serine hydrolase n=1 Tax=Candidatus Cryosericum hinesii TaxID=2290915 RepID=UPI001402C29A ----------------------------------SQNSNLPFGAASIIKLPVLVCVAQLVE -LGDLVWDRPIRLTVAAP-HGTGLLEYLDRSRWSVQDLCIMMMGVSDNMACNQLIEEI-GI -ERLNDVLHDLGYEATSIRRRMMDHE-MLARGIDNSVTAADIADMLARLYAHRLVSNEASQ -RMLGYLRMNQL-KDLIAWTLPGSAALAGKTGGMP-GSLLDAELVSVADGPTYSLCVFASG -FD-RAVQAKRLMTEVSERVYE-- ->[subseq from] serine hydrolase n=1 Tax=Brevibacterium luteolum TaxID=199591 RepID=UPI001404B095 ----LIDTVTALWNDLGAEGCFCVEDLETGQSI-SMNEDKRMPLVSVAKLSIAAALFAEDS -AGRIDARETVLIDPATATSGSTGISLFSDPVISLRDLTVQMFSVSDNAAADAVYDRV-GS -TAIGALHNELGIRSLRVHSPMRALFGMLSLNDINSGTVRGVATMLRLIHHGEVVSPDVSA -HLRRLMRTQVF-RHRIASGFPDTAEYYGKTGTLLT-YRHDAGVVTDIDGRSYAVVVFTRS -RIYSQPELDAAIGYSARL----- ->[subseq from] Beta-lactamase n=1 Tax=Youngiibacter fragilis 232.1 TaxID=994573 RepID=V7IBA0_9CLOT ------KEIKRYLEDRLGKYSFYFEDLKSGYIF-GYNEHVKMTSAGCMKLPVAMVVMKEIE -TGKLSLDQMVMVTEKDKVEGSGILKEFLEREYSIRELITVMLMDSDNTATQKLVSLL-GY -RNINSYIQEMGLKNTMMN--------DMPGSVINLTTSFDLSMCWKHLKNRSYINDENSQ -LLIDILKKQHK-KTKTAFYIPLKSRIASKPGDMD-GVENDTTLIELQKGD-FVFTIMSSE -LPNS-VYGLVSLAKAGKMIWD-- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora sp. TSRI0369 TaxID=1703936 RepID=A0A1Q5H1M3_9ACTN -------ELDAHLDKVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -TGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALAPPSACA -AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Uncharacterized protein n=2 Tax=unclassified Ruminococcus TaxID=2608920 RepID=A0A416QVC6_9FIRM ------------------------------------------------------------- -----------------------------------YSLLWDMITVSDNECYNELVRRVGGT -AVVNQYLRKNGYKNTGCHSSLHPSSSAWSSDGRNTASAKDCGMLLEKIYRGRCVSQQYSR -EMLNLLLHQTK-RYKIPSGLPAGVVCANKTGETSS-VQHDMAIIYGKKT-NYVLCIFSEG -ASED--HLLHGIRSISSRVYQ-- ->[subseq from] Beta-lactamase class A n=1 Tax=Micromonospora sp. CNZ297 TaxID=2572905 RepID=A0A559VDQ1_9ACTN -------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSFDSAGVPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGRLASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADSDDACRLIAHVSERV---- ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces sp. BK141 TaxID=2512171 RepID=A0A4R7GQD8_9ACTN ----IERRLRQVFSEAGCEGSVAALDVDSENRV-MFGDTEPMVAASTFKIVVALELFCQGV -EGTLDPTERVRLSPAEATPGQGFCIFEDDAEVSLRDVARMMLTISDNTATDLLIRRV-SL -SRVHDRLGRLGLDRIRLAGTIQQEFDSLRPGRITSATTGQMAALSRLIWLDRAGPAAACR -AVRTLLGQQRL-TRKIATGFGGEVRVAAKSGTLPGCASNDVGVVEYPDGSRFAVAVFTRP -AGRRTLPPDSVLGTAARLAVE-- ->[subseq from] Uncharacterized protein n=1 Tax=Agromyces aureus TaxID=453304 RepID=A0A191WG98_9MICO ---------TQALDDAGLTASITVRDLDTGREL-SLDPDAAYPLASVVKLPLAIAVLRGAA -AGSIALADPVRIDPAERTPLTGLCRFEHPSEVAVADLLYLAICVSDDTAADALFARA-SP -TEVTALLRELGITDITVRHSIQDLHEQLDVTHANAGTSRALVDLLERLWTSPDLAPE-RE -QLRRLLGQNLM-RHRLAPDLEDDAEWFSKTGTFLH-LRHEVGVLEHADGGTFAIAVLSES -SVRRQPGAEQALGFAARLL---- ->[subseq from] Serine hydrolase n=2 Tax=Candidatus Cryosericum TaxID=2498709 RepID=A0A398DER9_9BACT --------------------------------F-SQNSNLPFGAASIIKLPVLVCVAQLVE -LGDLVWDRPIRLTVAAP-HGTGLLEYLDRSRWSVQDLCIMMMGVSDNMACNQLIEEI-GI -ERLNDVLHDLGYEATSIRRRMMDHE-MLARGIDNSVTAADIADMLARLYAHRLVSNEASQ -RMLGYLRMNQL-KDLIAWTLPGSAALAGKTGGMP-GSLLDAELVSVADGPTYSLCVFASG -FD-RAVQAKRLMTEVSERVYE-- ->[subseq from] serine hydrolase n=1 Tax=Haloactinobacterium sp. HY164 TaxID=2675754 RepID=UPI0012B7911C --------ASSALEDAGLRGSFLVRDLDTGREL-GLEPDLLFPLASLVKVPLALDVLELAG -TGDLDLDEQVLIDATIRVPGATGLCRFTEPAIALADLLYLAVAVSDDTAAEALFRLC-PP -EQVTRRLRSMSVTDVTVRHTIGELHRQLDVSMANSGSARAMADVFERIWSGTDLRPGTSD -RLQELLAGNLLRHRLAPDLATDAASWASKTGTFLH-LRHEVGVVTHRDGGRFVVAALTES -RVTTQPVAEQTIGWVARMLHD-- ->[subseq from] serine hydrolase n=1 Tax=Pseudonocardia spinosispora TaxID=103441 RepID=UPI00040BC58E -----AETIAADWARLGVRGHLLARHLETGDQL-GFDVHTPVPLASVAKVPIALAVLDRIA -AGDLDPGLQITIAPEGKSFPTGIAAYRYPTTVAVADLVHQMLSVSDNASADTLVDLL-GV -DGIQRSLRDWGCPGIRFRHRMHRMYETLDPEHSNVASAAALVELLERIWLDDISVPGATA -ELRRLMGLQVF-TNRLSSDLRDTVRVSGKTGTFLN-LRHEIGVVTADSGDRVAIAALTRS -TRRATHDVDLAIGAAARTAF--- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora tulbaghiae TaxID=479978 RepID=A0A386WE77_9ACTN -------ELDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFHATE -AGRLDLDAPVPVRNSFDSAGAPRFWDRVGGEASLRWLAERIIVRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Serine hydrolase n=1 Tax=Sporolactobacillus sp. THM19-2 TaxID=2511171 RepID=A0A4Q4IHC3_9BACL ---AFTHDLSALVKPFGHHIAVEAVG-STGFHY-AHHADVPMLSASLIKLPILLYAVHRSL -SDSDFFDRKVRLPDENRVGGSGVLQILSGRDWSVRDLLALMINVSDNTATNLMLDLL-GI -GPVQTWARQHGFTDLRMERKMMDTAA-EKAGKKNMISAHDACRAIELIFPGG---QPVSE -EIGNWFLHQQF-RHKLPAELPDPVKVYNKTGEMNE-VDHDAALFTYQGHD-LYLAVLSEG -VK-DRQAVLNTIQRIG------- ->[subseq from] serine hydrolase n=1 Tax=Kocuria sp. WN036 TaxID=2032628 RepID=UPI000BAB344C ------------------------------------------------------------- -----------------------------GLGLTVEQALDVMISWSDNASGAALGQWL-GW -EQVEAFAHGQGFTATTFDPDTGSQDV-----VAMTTTPADVAALLERLRRGELLSGPSTV -LLMGFLEEQHL-DYALSSGFSPDVGFAHKTGLLVD-VSHDAGIVELGGH-DYVVAVLTDG -WS-DYEESAPWFGDAGR------ ->[subseq from] Surface protein PspA n=2 Tax=Faecalicoccus pleomorphus TaxID=1323 RepID=A0A380LNH4_9FIRM ------------------------------------------------------------- --------------------------------------LEAMIIDSDNTSYNILLQKLGGA -HKVNSFCEKLGLTRTEIHHGLVPGDGYFSDGKNNTTCPEDVAKFLELLYRSDVVSKAYSK -EMLELLKRCAD-DTGIVAGLAEGTECAHKSGWAD-AYYLDGGIIYTEYKD-YILVVFSDS -SYQKP------------------ ->[subseq from] Protein kinase domain-containing protein n=1 Tax=Chloroflexi bacterium 54-19 TaxID=1895928 RepID=A0A1Q3TC15_9CHLR ------AAISQALQSLPGATSVYIIY-PDGSFT-SDDGDRAQPSASVIKLWIAATAFQEAK -AGRLNLDENYTVQKTDIASGTGILVNNVGKTFTYEQILTTMLTYSDNSAANIVIKKLGGF -GKVNTYAQAHGYTSTKLQRLLGDISN----PNNNFTSGKDAATMMYLLSEGKVVDGNSSL -TILQALYDRRNDQNFFSPKLSADYNYLHISGTGTK-VRNEVGLVPIQNANNMIIAILDTG -VPDEGAAENAIAAAVG------- ->[subseq from] Beta-lactamase regulatory protein BlaB n=1 Tax=Mycolicibacterium chitae TaxID=1792 RepID=A0A3S4RH08_MYCCI --------------------------------VvDVGGTEPVVAASVYKVIVLVALARAFD -AGQLDPRASVRVVPADCTPGPTGLSLFSDPVLSWWDLARLMITLSDNAASDVILGAL-GL -AAVEAVIEDLGLTCTRVVGGTAALQRAFDPAYTTATSGADIIAVLNGIWTGTVATPDTCS -TMRAILAQQIW-PHRIRSGFPADVMVAGKTGTIGP-IRNEAAVVEMPGETPIAVAVFTRA -ARSDLPVVDAAIGRAAHLAV--- ->[subseq from] serine hydrolase n=1 Tax=Brachybacterium timonense TaxID=2050896 RepID=UPI000D0ACE90 --------------------------------LeSEDAARPVYAASTIKLHVLAAVLRAAD -AGRLDLTRTVPASRTFTGTGAAFTPTHPADGVSLDELAIRMIDRSSNEATDHLLEIV-GL -EAVAHEIDRLGLTATRVDRLIGDAA-AIEQGLTNESSPADLVSTLRSLMQGEGLSLRSRD -LARHALRAQRI--PIIATALRPGVPWGSKSGWVD-GYRHDVAAIGNPNGDERYLAVMTSG -MELT--AADEQIRALTRRL---- ->[subseq from] Beta-lactamase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=A0A328NN07_9ACTN -------DLDAHLDRVPGTVSAYVGRLAAPPTW-TRHADAGHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVVNDDSAQGAPRFWDRIGGTASLRWLADRMIVRSSNLATNLVLGHV-GL -PAVAEVWALAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGALASPAACT -TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT -DLDDEDDACLLLAHISAQVW--- ->[subseq from] Uncharacterized protein n=1 Tax=Actinobacteria bacterium 13_2_20CM_2_66_6 TaxID=1803492 RepID=A0A1Q7DKY3_9ACTN ---------------------------------------------------------ADGA -RGLLDLDERVVVG--DRVDGSGVLRHMRDLDLSLRDLAMLSIIVSDNTATNRLIERV-GL -GRVGERLREWGCSRTQLTRKMYDFEAA-KRGHENVMTPRETVSLLLRLHRGECEDRATSD -AVLAVLEQCQD-RTMLLRYLPYGTKVPHKTGTLDE-SRNDAAIV--PGDRPVIVAAFTRK -VRDT------------------- ->[subseq from] Serine hydrolase n=1 Tax=Streptomyces lavendulae TaxID=1914 RepID=A0A5C8GX07_STRLA -----EDQVRAIFERAGCMGTLLVQPLDEEREF-GLGADQLVVPASVMKVLVALAAETWFA -EGRLELRERVVLGAAGRTPGPVGLSLLADDVLSWRDMVVLMLTISDNPCTDALMNRL-GV -GTLNATAARLGLRNTVVRSDVRTLLYAPAPGAGTRTTARDMVRLLRLLWSGQAGPAEACA -RVRAVMARRLT-RHRIASGFRTPVRVAAKSGGLAGIVRNEVGVVSYPDGRRYAAAVFTRS -RTADESAINAAIGAATAHA---- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora purpureochromogenes TaxID=47872 RepID=UPI0004C2B701 -------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVAVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSGCA -AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] serine hydrolase n=1 Tax=Kocuria rhizophila TaxID=72000 RepID=UPI000DD3F311 -----EAAVEELAAGVPGELGLVVLDPDGRPVV-TRAAERSFTSASLYKLFVAHAVLERVD -RGEAALTDPV-----------------PGTALTVAQALDAMITWSDNASGAALGGQL-GW -DALEDSARAHGFTTTTFDPGTGE-----DGIVAMTTTPDDVADLLERLRRGRLLSPASTE -LFLGLLRDQHL-DYALSSGLSAGTEFAHKTGLLED-VSHDAGLLRTGGRE-HVVVVLTD- ------------------------ ->[subseq from] serine hydrolase n=1 Tax=Actinoalloteichus hymeniacidonis TaxID=340345 RepID=UPI0008528D27 --------------------RLHALSLTTDREV-GADPDTPVVLASVVKVLIALEYARQAT -AGLLDPTSMVWVRDGDRLGGTGTAGFLDDVALSLRDLAGSMMSVSDNTAADLLLDRI-GL -AALRSAIGELGLGATTVLGAPRDILAAFDPAGTTSSTPRDMTRLLSLIWRDLAGSAAACA -EVRRLMSAQLN-WHRLAAGFDDEVLVAAKSGSLPP-IRNEIGVITYPDGRGYAVSVFVEL -TGGRRPDVDVAIGRAARLAVD-- ->[subseq from] Serine hydrolase n=1 Tax=Ruminiclostridium sp. TaxID=2053608 RepID=A0A357AJV7_9FIRM ---EIKAKAEDFISKQSGKYGVYFIDLATGEYF-GINDRDEYIAASTTKLPMNLFLYTKIE -SGEVDLESKLKYLKEDFEAGTGIIQNQPGTEYTVRETSRLSIIHSDNCGINMIIRVL-GI -ENICNYILDLG--------------GDIYYDDRHRTSPHDLGLVTQELYRLYLNNPELYG -EMIYNLENTDW-EDRISAKLPAEVKVAHKIGNQVR-TANDVGIVFAS--HPFVLAVMTKD -VD--FGTACNKIADLSKMIYDE- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora arida TaxID=2203715 RepID=A0A3N9XL88_9ACTN -------DLDAHLDRVPGTVSAYVGRLDAPPTW-TRHADAGHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVVNDDSAQGAPRFWDRIGGTASLRWLADRMIVRSSNLATNLVLGHV-GL -PAVAEVWALAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGTLATGALASPAACT -TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT -DLDDEDDACLLLAHISAQVW--- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Rokubacteria bacterium TaxID=2053607 RepID=A0A2V6RU35_9BACT ---DLVTRMNALCDALPFQTSWYLKDLATGETA-NRLGDTPVPSASTRKISIMMAALKAVH -DGKLALDQKVTIDAKYQDNDSGTFQHLTPGFISFRDALVMMIIVSDNTCTGTVVDLV-GL -GEIQRFCESIGMSRTVHRFGIPRLGPDHSLDQVTTTTPSDQGLLLEMILRGVGSTPELCR -LGLDILSWQKL-KTRLPSLLPLGTKVAHKTGTGSR-GFMDAGIVFKDDHPLFILTAYTEH -VPAALPD---------------- ->[subseq from] Beta-lactamase/transpeptidase-like protein n=1 Tax=Gonapodya prolifera (strain JEL478) TaxID=1344416 RepID=A0A139A0J8_GONPJ -----LSELAAIEPSSRGSIGVAALATAAPPAI-SFNADQRFPMASTVKVGLAATVLKLIE -RGKLALDLVVEVEDFDLCIYPEIVWGHLPAFFAVSNLLEMSLTRSDNTATDVLLKLIGGP -PTVRKYLDELGVPAMNPKSNMRDN-LAVEGDVRDSTTPAAYHTFLRLALSAHLLSPSMSA -YLLAAMSRCLS-TERIRGRLRPGVPTSVKGGSVR-GNHSEVGVVEVEGRGWITLAIYTRN -APTPMSIRERTIADVARLVYDYy ->[subseq from] Uncharacterized protein n=2 Tax=Candidatus Woykebacteria TaxID=1817899 RepID=A0A1G1WTZ2_9BACT -------------TDKQGDYAIAIKNLTTNESF-ELNQDKIFTSASLYKLWVMATAFDQIN -SGNLDLSRDIAYLNKKFFIPPDYAELTKGGILSVRSAIEQMITISHNYASLLLTDRI-KP -ESIVSFLKNYEFNGSKFGTE-AD---------PPTTTASDIALFFEKLSNGTIINRGYSD -RMLDVLKRVKR-VDKLPKYLPEAALIAHKTGELDY-FTHDGGIVYGPKG-PYIIVVLTET -KS--PPDAQETIANISKAVYNYf ->[subseq from] Beta-lactamase class A n=1 Tax=Streptomyces atratus TaxID=1893 RepID=A0A1K1YHP9_STRAR ------------SAALPLTLAVAAVDIDGGGTV-GVDERTVLPVASASKLLLLAEVARRLD -TGELPADRVVEVLDEDLAEGTGLLRRLSGRGWTVEDLAWLTASVSDNTATNALLRLV-GR -ESTARLAQELGLDHLTLHDKVRDVRGPDVPPVFATGTAHDLARLVTHAVRGTMSCPAASA -RLLRWMRSNTD-HGLVPALVDDGLLVANKTGTDT-GVRADAGVIIGRRRLAYAVVARWDT -ALSTERAAVHAIRDVGRTL---- ->[subseq from] Serine hydrolase n=1 Tax=Peptococcaceae bacterium TaxID=2052179 RepID=A0A419G5S2_9FIRM ---PLKKQLESYLATRKATYGIYFKDLNTGATW-GINDLTPIPAASTIKVPYVLYLNEQVA -AGRLKMEQRIAYDSNDYAGGSGYLKETAADGFTLRVLSNLAITLSDNVAYKMI-KRVTGE -ENVLAYMKAMGGTTI-------------GGNGQDNTTARDMAAYMEGVINFSRRNPALGN -RLIDDLANPIW-HYGLPGKLPDNVKVAHKEGDLP-GVSNDVGIVFAS--RPYIISILSMN -QD-NIEQGFLDISEISGMIYEY- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora saelicesensis TaxID=285676 RepID=UPI000DC3D9DB -------DLDAHLDRVPGTVSAYVGRLAAPPTW-TRHADAGHYAASTMKVAVLAALHRAAE -AGTLDLDAPVPVVNDDSAQGAPRFWDRIGGTASLRWLADRMIVRSSNLATNLVLGHV-GL -PAVAEVWALAGARNSVTGRGIEDFAAR-EAGITNTVTAADLAALLGALATGALASPAACT -TMLDVLLAQEH-REDLAAGLPEGTRIAHKNGWVR-GVRHGAGVVLPDDAPPYLIAVCTTT -ELQVEDDACLLLAHISAQVW--- ->[subseq from] Serine hydrolase n=1 Tax=Brevibacterium aurantiacum TaxID=273384 RepID=A0A556C507_9MICO ------REVGDQLEAAGLRARIMVRDLDSQAEI-SVGSDVSLPLASVVKVPIALAVLSRIA -SGKLEADRQVLVEPGQFKPSSTGTSRFRHPAIAVDDLLMLSVCFSDNTATDALLQLV-PI -ELVQRELADLGFGEIQVRHHLDALVRQLDSAQANVATASVLTELLAQLWRPDRISPAVAT -RLRELMAGNVVRHRLAPDLMSDAARWSSKTGTLLH-LRHEIGVVEHADGQTIAVVVLSES -RNAVQPAAEAALGAAARALHD-- ->[subseq from] Beta-lactamase class A n=1 Tax=Nocardioides sp. YR527 TaxID=1881028 RepID=A0A1G9A7P9_9ACTN ----LAEATAERFQELRVRVAFLARDIDTGHEI-GVGGDRPMPLASVAKVPLALVVADRIA -RGEIDGGAMVTLTAAERSYPYGISAFAHDATCSVADLMLMMLGLSDNAAADALFDRV-SP -REVDEQLAEWGVEGLRVRHRMQPMYDSLDVERATVGSPRACVDLLERVWRDEVAKPEATE -LVRRLMGKQVF-THRIAALLADDIHLAGKTGGFLT-LRHEIAVVTHPGGR-VAIAVLTDS -DRTAQNDVDLAIAATARD----- ->[subseq from] hypothetical protein n=1 Tax=Bacillus rubiinfantis TaxID=1499680 RepID=UPI0009E3C7CD ---KLSTELKSYLKKTGGKVTIQYKDLSTGDVF-QINGKSSGRAASTIKLPLALYVMEQAS -KGKINLNKTLTYKSYHYFGGSGIIQKKVGTKFTIRQLVKYAMIYSDNIAFIMLKEYV-GA -SNFQKYMNSIGGQ------------YAYPRNGQTITSANDLTIYATELYQFSE-KNKYGK -ELVGYLKETVY-NTTIPRGIK-GVPIAHKVGMIPSLIYNDVAIVY--DKRPFVLAIMTQG -IA--YEKSQKVIADIAKIVYKH- ->[subseq from] Serine hydrolase n=1 Tax=Fusobacterium varium TaxID=856 RepID=A0A250LQR7_FUSVA -----EKRIKEIINENSGVAGVVIRD-SFGKLL-MINEEVVFPSASIIKLFILMALN---- ---KEDYNKRIELKKVDKVGGCGILKVMEDGLLTVKDTAYLMICLSDNTATNILIDYI-GM -DKINACIKEKGFTGTVLGRKMMDAEAR-KAGKDNFTTPKDVLGVLKMLCKNP-------- -DDLDMLRNQAY-NNKIPLYFAREVDFAHKTGELMY-IEHDAGRLFFDGG--WVDVIVLTK -DLEKNEDGIKINSLIGKVIFDNy ->[subseq from] serine hydrolase n=1 Tax=Micromonospora sp. RV43 TaxID=1661387 RepID=UPI00064BAA12 -------DLDAHLDRVPGTVSAYVGRPGARPTW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSFDSAGVPRFWDRVGGEAPLRWLAERMIIRSSNLATNICIGQV-GL -PAVAQAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAAVLGELALGALASPAGCA -AMLDVLVAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSERVW--- ->[subseq from] Beta-lactamase class A n=2 Tax=Micromonospora siamensis TaxID=299152 RepID=A0A1C5HI83_9ACTN ---------EEIYGQAGISGALHVVDVDAAREV-AVRADQQIVIASVFKILLVLEFARQAV -AGQLDPTERVLVRAADRLGGWGVAGCADDVEISLRDLAYFTMSVSDNTAADLLLRRV-GP -DVPAMLAAELGLPRTRIVGGPRQLVEVFDPERTTSSTAREITRLLGLVWRDEAGPPAACA -MVRELMGRQLF-WTRLAAAFPPGVRVAGKTGNLP-GLHLEAGVAEYPDGRRYAILVHART -ERLS------------------- ->[subseq from] serine hydrolase n=1 Tax=Micromonospora chalcea TaxID=1874 RepID=UPI000CE4AD6D -------ELDAHLDKVPGTVSAYVGRPGARPAW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVARAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSACA -AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSARVW--- ->[subseq from] Beta-lactamase class A n=2 Tax=Thermaerobacter TaxID=73918 RepID=K6P328_9FIRM ------ARVREFIETRPQTFGIYFKDLQTGATW-GINEREPIHAASTIKVPLVLYVNHQVA -AGRARMDDRIVYEPDDLTGGAGILQRFPGKSYSLRVLTNLSITISDNVTTNMLFRHF-GK -DNVGEFMRRLGGEVIF------------PG-GRRISTARDMGIYVEAVLDFARQHPLLGG -RMLDDMGHAIF-HVGLPGELPPDVFVAHKEGDIE-GVADDVGIVF--GRRPFVLAVLSKG -VD-NIDQGFEDIARISKIVYD-- ->[subseq from] Serine hydrolase n=1 Tax=Micromonospora sp. XM-20-01 TaxID=2583240 RepID=A0A505HB76_9ACTN -------ELDAHLDKVPGTVSAYVGRPGARPAW-TRRADATHYAASTMKLAVLVALFRAAE -AGRLDLDAPVPVRNSSALPGAPRFWDRVGGDAPLRWLAERMIVRSSNLATNICIGQV-GL -PAVARAWALAGARHSVTGRGIEDFAAR-DSGIDNLVTAADLAALLGELALGALASPSACA -AMLDVLAAQEH-REDLAAGLPDGTRIAHKNGWVR-GVRHGAGVVFPDDAPPYTIVVCTTT -DLADEDDACRLIAHVSARVW--- ->[subseq from] serine hydrolase n=1 Tax=Streptomyces sp. SID685 TaxID=2690322 RepID=UPI00136914C4 ----------EIFERAGCTGTLLVQPLHGEGEF-GLDADQLVVPASVVKVLVALAAETWFA -EGRLDPRERVVLGAARRTPGTVGVSLFEDEVLSLRDMVVLMLTISDNPCTDALMNRL-GV -DTLNATAARLGLRNTVVRSDLRTMLDALTPGTGTSTTARDMVRLLRLLWSGQAGPAAACA -RVRAVMGRQLT-RHRIASGFRAPVRVAAKSGGLAGIVRNEVGVVSYPDGRQYAAAVFTRS -RPADDAAINAAIGAATAHAV--- ->[subseq from] Uncharacterized protein n=1 Tax=Kocuria sp. CNJ-770 TaxID=1904964 RepID=A0A1Q9SF54_9MICC ---TLADDLEQLALGVPGELGLVLLGPDGNELA-SRAADRPFTSASFYKLFVAHAVLERVD -RGELALDDPVP-----------------GSALTVGTALAAMISWSDNPSGAALGRWL-GW -AELEEFAHGHGFPATTFDPDTGDADRV-----AMTTTPADVAALLERLRRGELLSPASTA -LFRQLLEDQQL-DYALPSGFSPGTAFAHKTGLLED-VSHDAGLLTLDGRE-HVVVVMTD- ------------------------ ->[subseq from] Uncharacterized protein n=1 Tax=Candidatus Levybacteria bacterium CG10_big_fil_rev_8_21_14_0_10_36_7 TaxID=1974632 RepID=A0A2M6W8D9_9BACT -------VVEKFIKEQGPKFSIYYKNLKTGASF-GVDENKILTAASLNKILIASYLYNQAD -RKKIDLEEKITIQEKDLQDGTGIRYEGAGGVYTLKTLAKLALEQSDNTAAFVLSEKL-GR -GEIEEYGKSLGLVTTNIA--------------DNKTSAKDMGILLELIFNRKIANNALTL -EFLDFMKDTDF-EDRLARDLPKSVAVYHKAADGIS-LVHDAGIIGDENF-PFILSILTNE -VR-DEEEVKKTIGQITKFIYD-- ->[subseq from] Serine hydrolase n=1 Tax=Candidatus Levybacteria bacterium TaxID=2052151 RepID=A0A4P5UKK3_9BACT -----DDVVRNSQEGTRGNYAIVIKNLKSNDIF-MQNEHLVFESASLYKLWVMGAVYKQIK -EGKIKEDDILSWDISLLNNESPSLGELSSGVLTVSDALHQMITISHNYSALMLVEKI-GI -SNLKKFIQELGLKETFVDNHS-------------RTTAYDLVIFFEKLYNGQIIDKKYSN -KMIALLKDQQI-NDRIPRFLPKSISIGHKTGEIDN-FKHDAGIVFAPKGD-YIFIVLTKS -ESP--VGAAERIATLSKEIFEFf diff --git a/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv b/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv deleted file mode 100644 index 2f2087e..0000000 --- a/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015.csv +++ /dev/null @@ -1,4997 +0,0 @@ -,mutant,0,39,156,625,2500,cefotaxime,0_1,0_2,10_1,39_1,39_2,156_1,156_2,625_1,625_2,2500_1,2500_2,km,vmax,mutation_effect_prediction_vae_ensemble,mutation_effect_prediction_vae_1,mutation_effect_prediction_vae_2,mutation_effect_prediction_vae_3,mutation_effect_prediction_vae_4,mutation_effect_prediction_vae_5,mutation_effect_prediction_pairwise,mutation_effect_prediction_independent -0,H24C,0.022702344,0.045890139,-0.025738193,0.018871156,-0.418259925,-0.031940758,-0.037094619,0.082499307,0.002591313,-0.042346297,0.134126575,-0.010196878,-0.041279508,-0.014684342,0.052426653,-0.319356518,-0.517163332,0.785765464,1.519963852,,,,,,,, -1,H24E,0.011387119,-0.012635759,-0.018954701,-0.0204358,-0.279024169,0.016456014,0.013497391,0.009276846,0.054103653,-0.01967789,-0.005593628,0.001570742,-0.039480144,-0.034798015,-0.006073584,-0.200042482,-0.358005855,0.757582777,1.502589239,,,,,,,, -2,H24D,0.042301356,0.017005294,0.018951436,0.006742876,-0.18160661,-0.030325921,0.033849314,0.050753398,0.002764374,-0.007401458,0.041412046,0.017489834,0.020413037,-0.02608598,0.039571732,-0.155937758,-0.207275461,0.763289728,1.622027556,,,,,,,, -3,H24G,0.01146042,-0.024511458,-0.023807149,-0.01720911,-0.060241673,-0.009657341,-0.000471827,0.023392666,-0.013742003,-0.040919201,-0.008103714,-0.02192628,-0.025688018,-0.028224614,-0.006193606,-0.043527004,-0.076956341,1.099627807,1.736940857,,,,,,,, -4,H24F,0.020598952,0.020320945,-0.015905298,0.016190193,-0.818487096,-0.000809311,0.021397399,0.019800504,-0.001590688,-0.045411124,0.086053014,-0.01345311,-0.018357485,-0.008856131,0.041236516,-0.493981846,-1.142992345,1.074944348,1.574922918,,,,,,,, -5,H24I,0.008072384,-0.002722445,-0.039291543,-0.00968701,-0.359191243,-0.009312377,-0.001629498,0.017774265,-0.068626848,-0.019115145,0.013670255,-0.032591789,-0.045991296,-0.027839389,0.008465369,-0.292563068,-0.425819417,0.847920402,1.518735794,,,,,,,, -6,H24K,0.039887617,-0.002490981,-0.019397019,0.00610538,0.014469577,-0.003065117,0.052906255,0.026868978,0.164192036,-0.019079924,0.014097962,-0.013887172,-0.024906865,-0.007384306,0.019595066,0.029525026,-0.000585873,0.326024656,1.416118181,,,,,,,, -7,H24M,0.025373797,0.012340427,0.024713301,0.028739506,-0.224781293,-0.026146539,0.02684011,0.023907484,0.182675441,-0.006794296,0.031475149,0.00551956,0.043907042,0.010168857,0.047310154,-0.146503843,-0.303058742,1.110067341,1.894424063,,,,,,,, -8,H24L,-0.007130208,-0.024791695,-0.011061763,-0.011754145,-0.480346576,-0.001964848,-0.010297589,-0.003962826,0.00735616,-0.009807279,-0.03977611,0.009071989,-0.031195515,-0.006225547,-0.017282742,-0.306059807,-0.654633344,1.023505724,1.645245487,,,,,,,, -9,H24N,0.007222492,-0.010835478,0.016865982,0.007656297,-0.043093163,-0.008911973,-0.002849495,0.017294479,0.08085483,-0.010625522,-0.011045434,0.01749522,0.016236744,-0.014733888,0.030046481,-0.006558292,-0.079628033,0.995525066,2.060699369,,,,,,,, -10,H24Q,0.006029993,-0.008585199,0.004985719,-0.016438516,-0.135568334,0.001497615,0.00969967,0.002360316,-0.013783367,-0.010388462,-0.006781935,0.011864976,-0.001893539,-0.033507198,0.000630166,-0.084767134,-0.186369533,2.437793081,2.747970799,,,,,,,, -11,H24P,-0.133874583,-0.082345722,-0.072931638,-0.417904623,-1.010848138,0.67096666,-0.112957484,-0.154791682,-0.744292983,-0.129206405,-0.035485038,-0.084989922,-0.060873354,-0.19933237,-0.636476876,-0.924415785,-1.097280491,2.983480558,2.787875051,,,,,,,, -12,H24S,-0.008154447,-0.034115248,-0.020574225,-0.01582124,0.036166097,0.002793464,-0.024719945,0.008411051,-0.018904125,-0.030762357,-0.037468138,0.013887272,-0.055035722,-0.013632758,-0.018009721,0.068115045,0.004217149,2.225154604,2.659353477,,,,,,,, -13,H24R,0.01683236,-0.009190524,0.004127683,-0.004182925,-0.002526258,0.031088454,0.017507484,0.016157236,-0.079373389,-0.029775986,0.011394938,0.006579872,0.001675493,-0.023271806,0.014905956,-0.008315397,0.003262881,1.546473607,2.938183126,,,,,,,, -14,H24T,0.02039927,-0.01458811,-0.007601924,-0.004795582,-0.067187546,-0.022489463,0.018380054,0.022418486,-0.00299271,-0.037083703,0.007907483,-0.000237405,-0.014966443,-0.016221578,0.006630414,-0.04873158,-0.085643512,1.407678003,2.285347998,,,,,,,, -15,H24W,-0.006307298,-0.000633045,-0.029192701,-0.010615592,-1.347585961,-0.015026478,-0.006286516,-0.00632808,-0.038247648,-0.036022839,0.034756749,-0.031301744,-0.027083658,-0.030208583,0.0089774,-0.999196822,-1.695975099,1.04687351,1.421552326,,,,,,,, -16,H24V,0.026710718,-0.010529573,-0.005339989,0.006753803,-0.026874047,-0.005140612,0.022703225,0.03071821,0.05573437,-0.015589325,-0.005469821,-0.013335158,0.00265518,-0.013740954,0.02724856,-0.001619701,-0.052128393,1.224564307,2.138393446,,,,,,,, -17,H24Y,-0.021573751,-0.047011483,-0.023488168,-0.033551258,-0.88502515,-0.015438488,-0.030115288,-0.013032213,-0.034730469,-0.048617681,-0.045405285,-0.006905626,-0.04007071,-0.038534926,-0.02856759,-0.588959987,-1.181090312,1.921541658,2.138059625,,,,,,,, -18,P25A,-0.103866038,0.001748125,-0.004218662,-0.053582423,-1.642595093,0.120518217,-0.083327717,-0.124404359,0.014370958,0.034530088,-0.031033839,0.032673877,-0.0411112,-0.036225351,-0.070939495,-1.430707001,-1.854483185,2.467386436,2.150571057,,,,,,,, -19,P25C,-0.035211365,0.086712403,-0.068334711,0.009652236,-0.364138405,0.1279877,-0.020434406,-0.049988324,-0.054549701,0.101310071,0.072114734,-0.191309107,0.054639685,0.047170985,-0.027866513,-0.195560504,-0.532716305,1.9294107,2.312449074,,,,,,,, -20,P25E,-0.011457154,0.041199839,-0.0000543,-0.010716764,0.143257861,0.111450601,0.02865962,-0.051573928,-0.074597621,-0.01477754,0.097177218,-0.00321029,0.00310163,-0.008045502,-0.013388026,0.149960974,0.136554748,1.590983034,3.812283434,,,,,,,, -21,P25D,0.004797193,0.025658574,-0.060980488,-0.037705233,-0.028402505,0.046607841,-0.006968291,0.016562677,-0.029385042,0.006194666,0.045122482,-0.063908131,-0.058052845,-0.028843079,-0.046567387,0.016735672,-0.073540682,1.165591923,1.75016223,,,,,,,, -22,P25G,-0.02390934,0.00857487,0.02089776,-0.007906312,-0.969267861,0.039196438,-0.01376224,-0.034056439,0.015377403,-0.013636435,0.030786175,0.007073728,0.034721791,-0.011556967,-0.004255656,-0.649078606,-1.289457116,1.174220101,1.567403802,,,,,,,, -23,P25F,-0.012487661,-0.042772745,0.075685598,0.033886088,-0.199804031,0.066925464,-0.049121473,0.024146152,0.101493638,0.003571726,-0.089117216,0.083675768,0.067695427,0.024388934,0.043383241,-0.137551135,-0.262056927,0.964024176,1.704042231,,,,,,,, -24,P25I,-0.028071818,0.024272005,0.016421708,0.02703638,-0.073523836,0.021876117,0.048925754,-0.10506939,-0.045495239,0.030187245,0.018356764,0.070782746,-0.037939331,0.001924393,0.052148366,-0.047404682,-0.09964299,0.495339261,1.521717066,,,,,,,, -25,P25H,0.029477973,0.040318719,0.063971249,0.07258627,0.045784618,0.07333674,0.013637671,0.045318274,-0.003241712,0.074293521,0.006343916,0.083780657,0.044161841,0.137057045,0.008115495,0.106692283,-0.015123047,0.397834768,1.463720776,,,,,,,, -26,P25K,-0.066288891,0.117252092,0.009166947,0.072576088,0.135590499,0.020043081,-0.02721235,-0.105365432,-0.006021206,0.116714876,0.117789308,0.042032786,-0.023698892,0.154531417,-0.009379241,0.153679558,0.11750144,0.846087489,1.542000952,,,,,,,, -27,P25M,-0.09282261,0.029051416,0.006452597,0.039816967,-0.02836574,0.050932846,-0.052520568,-0.133124651,0.040635808,0.050526799,0.007576032,0.060013935,-0.047108741,0.117886074,-0.03825214,0.010015825,-0.066747305,0.188973702,1.759942865,,,,,,,, -28,P25L,-0.005307256,0.002001949,0.011836247,0.008659517,-0.211868922,0.064513297,-0.002101309,-0.008513203,0.015368952,0.00376092,0.000242977,-0.002386983,0.026059476,0.04727512,-0.029956087,-0.122705077,-0.301032767,1.945234964,2.369792706,,,,,,,, -29,P25N,-0.051559887,0.039733466,0.070335003,0.004724437,0.020640486,0.036064769,0.031452377,-0.13457215,-0.027886684,-0.035975711,0.115442642,0.031178818,0.109491187,0.01069026,-0.001241387,0.014249977,0.027030995,1.104388073,2.143068318,,,,,,,, -30,P25Q,0.138010463,0.011568189,0.063431807,0.108373029,-0.028213622,0.078609402,0.091898126,0.184122799,0.032167147,0.021135016,0.002001361,0.020337831,0.106525782,0.064379082,0.152366976,-0.019924656,-0.036502587,1.208210385,2.58900106,,,,,,,, -31,P25S,-0.039348434,0.004380082,-0.003944659,-0.018238771,-0.160130436,0.030006567,-0.013738251,-0.064958616,-0.055818152,-0.026092678,0.034852842,0.018987832,-0.026877149,0.006671651,-0.043149192,-0.150924537,-0.169336335,1.406720565,2.237189096,,,,,,,, -32,P25R,-0.013706154,0.005957286,-0.014669933,-0.046117531,0.054153993,0.156314831,-0.000248097,-0.02716421,-0.089279396,-0.021879775,0.033794347,-0.029032602,-0.000307263,-0.098906076,0.006671015,-0.002867978,0.111175963,1.251916214,2.535180898,,,,,,,, -33,P25T,-0.076933927,-0.007848001,-0.006919319,0.001024136,-0.091199948,0.000353426,-0.026131054,-0.127736799,-0.017982202,0.00335265,-0.019048652,-0.009112019,-0.004726618,0.013580427,-0.011532155,-0.04988034,-0.132519556,1.24094672,2.425970024,,,,,,,, -34,P25W,0.013600484,0.050044448,0.073206825,0.029595033,-0.109138595,0.030245566,-0.003221456,0.030422423,0.003972373,0.061866422,0.038222474,0.024107118,0.122306531,0.045284397,0.013905668,-0.051122111,-0.167155079,1.169687228,2.435839065,,,,,,,, -35,P25V,-0.027791513,0.025620063,0.022951329,-0.010637382,0.045912991,0.100840981,-0.022572752,-0.033010274,-0.052321226,0.014312122,0.036928004,0.015046284,0.030856374,-0.011038731,-0.010236033,0.047570831,0.04425515,1.129039789,2.788424151,,,,,,,, -36,P25Y,-0.094727201,-0.008258924,-0.022609935,-0.03167515,0.001744668,-0.082969713,-0.136345006,-0.053109395,0.015099744,-0.003688568,-0.01282928,0.029174483,-0.074394353,-0.013321733,-0.050028567,-0.006304549,0.009793885,1.228984057,2.537046097,,,,,,,, -37,E26A,-0.060088714,0.035019974,0.046009,0.074834899,0.010913108,0.070260149,-0.06167179,-0.058505638,0.090042438,-0.011974944,0.082014892,0.03097157,0.061046429,0.023863482,0.125806315,-0.011478437,0.033304653,1.220418406,2.754342831,,,,,,,, -38,E26C,0.051185296,0.083383352,0.078881787,0.072504124,-0.158232612,-0.067113079,0.061477543,0.040893049,0.147844696,-0.004150286,0.17091699,0.024473769,0.133289805,0.031847367,0.11316088,-0.147334969,-0.169130254,1.319927096,2.178389478,,,,,,,, -39,E26D,-0.134622252,-0.048278454,0.029866107,0.027840852,-0.07578524,0.083496095,-0.127368362,-0.141876142,0.082220783,-0.128399269,0.031842361,0.049190666,0.010541547,-0.009290076,0.06497178,-0.073498399,-0.078072081,1.160453271,2.203032084,,,,,,,, -40,E26G,0.074308788,0.223560228,0.171847288,0.179592065,0.081310077,-0.027626518,0.012129959,0.136487616,0.172252043,0.146756386,0.30036407,0.164787368,0.178907207,0.13317435,0.226009779,0.063616102,0.099004051,1.189518643,2.987475843,,,,,,,, -41,E26F,-0.020927228,0.052075812,0.062112092,0.085250613,-0.232106116,-0.10336064,-0.017165364,-0.024689091,-0.065045921,0.065483923,0.0386677,0.113509275,0.010714908,0.127749714,0.042751512,-0.091720963,-0.372491268,1.1686605,2.305963479,,,,,,,, -42,E26I,-0.046781981,0.089236684,0.089213575,0.103174965,-0.153907493,-0.044398892,-0.072168265,-0.021395696,0.130412738,0.07330538,0.105167987,0.08943488,0.088992269,0.117652059,0.08869787,-0.138097757,-0.169717228,1.252476759,2.191690605,,,,,,,, -43,E26H,-0.043425119,0.082855565,0.083513347,0.114422615,0.020916837,0.010849126,-0.086416719,-0.000433518,0.07944541,0.049495962,0.116215168,0.085745016,0.081281677,0.113490903,0.115354327,0.025989434,0.015844239,1.261017122,3.025741946,,,,,,,, -44,E26K,-0.038926874,0.058490223,0.039393068,0.086518878,0.087119809,0.041040865,-0.046154832,-0.031698916,0.154969402,-0.0632611,0.180241545,-0.001884144,0.08067028,0.018855342,0.154182414,0.011954357,0.16228526,1.090470615,2.610276223,,,,,,,, -45,E26M,-0.022183284,0.074443098,0.09094756,0.118748545,-0.036440986,-0.053481152,0.011119258,-0.055485825,0.306981506,0.083463289,0.065422907,0.145623335,0.036271785,0.130202977,0.107294113,-0.005214771,-0.067667201,1.218124703,2.751691742,,,,,,,, -46,E26L,0.010543748,0.082944389,0.076037929,0.091447172,-0.05818041,-0.021525499,0.000614657,0.020472838,0.099935417,0.003116839,0.162771939,0.048573676,0.103502182,0.004616994,0.17827735,-0.079421767,-0.036939052,1.135646515,2.215761726,,,,,,,, -47,E26N,-0.031657324,0.060627192,0.091066853,0.039984992,-0.006468797,-0.053321327,-0.0442747,-0.019039948,0.229094262,-0.0000949,0.121349284,0.127210553,0.054923153,-0.013103046,0.093073029,0.018903217,-0.03184081,1.204694658,2.929347525,,,,,,,, -48,E26Q,-0.020517156,0.08404489,0.04875523,0.064826026,0.049690653,-0.005371125,0.000764699,-0.041799011,-0.00472684,0.098069679,0.070020101,0.100251745,-0.002741286,0.08672771,0.042924342,-0.047413247,0.146794553,1.215644385,2.565032077,,,,,,,, -49,E26P,-0.013258715,0.093119437,0.069852749,0.066757808,-0.387232365,-0.010640994,-0.020444549,-0.00607288,0.121882909,0.034911035,0.151327838,0.048987795,0.090717702,0.028017465,0.105498151,-0.323835808,-0.450628922,0.862287849,1.588808813,,,,,,,, -50,E26S,0.008822045,0.062530196,0.084343423,0.066269137,-0.039584928,-0.00190877,0.015906523,0.001737566,0.093909764,0.01396951,0.111090881,0.037997407,0.130689439,0.018650728,0.113887546,-0.063170402,-0.015999453,1.425051198,2.473002397,,,,,,,, -51,E26R,-0.034878101,0.064167344,0.056959896,0.064815187,-0.220002694,0.055094485,-0.04941712,-0.020339082,0.06200121,0.001093115,0.127241572,0.019034356,0.094885435,0.016606558,0.113023815,-0.233019957,-0.20698543,1.216399974,1.927173917,,,,,,,, -52,E26T,-0.068693308,0.067196764,0.091103084,0.065580673,-0.135908892,-0.047085287,-0.082941395,-0.054445221,0.140445519,0.040813172,0.093580356,0.113968603,0.068237565,0.063663484,0.067497861,-0.126344867,-0.145472917,1.342091145,2.282051505,,,,,,,, -53,E26W,-0.077143388,0.078134304,0.131062156,0.05794898,-0.442340179,-0.007556826,-0.099702913,-0.054583863,0.127188408,0.107484662,0.048783945,0.158286969,0.103837343,0.076026447,0.039871512,-0.282806958,-0.601873399,0.753185228,1.574413952,,,,,,,, -54,E26V,-0.021916136,0.116771963,0.098093522,0.076206856,-0.064567429,0.053498728,0.001364787,-0.045197059,-0.005312537,0.054057513,0.179486412,0.095287693,0.10089935,0.063602831,0.08881088,-0.0759068,-0.053228057,1.14355857,2.291450463,,,,,,,, -55,E26Y,-0.050049098,0.056360349,0.082999386,0.068513351,-0.245436276,0.008291246,-0.053024215,-0.04707398,0.169991469,0.029324085,0.083396613,0.065728571,0.1002702,0.026829566,0.110197135,-0.131694768,-0.359177783,1.238381025,2.122608572,,,,,,,, -56,T27A,0.01357957,0.039949606,0.057111746,0.013452565,-1.454588308,0.032397485,0.017141401,0.010017739,-0.035744448,0.005885989,0.074013222,0.050484313,0.063739178,0.038931638,-0.012026509,-1.327074491,-1.582102125,0.584924165,1.322045675,,,,,,,, -57,T27C,0.018866531,0.064055143,0.055018944,-0.164647789,-2.419022561,-0.02408756,-0.000750725,0.038483787,-0.087721879,0.025631016,0.10247927,0.074124041,0.035913847,-0.064575672,-0.264719906,-1.851261728,-2.986783394,0.782459136,1.307603573,,,,,,,, -58,T27E,-0.060106353,-0.035422838,-0.733435853,-2.021893943,-2.414464268,-0.084510018,-0.055243239,-0.064969466,-0.05644945,-0.028293325,-0.042552351,-0.340185302,-1.126686403,-1.937002238,-2.106785647,-2.048521205,-2.780407331,1.601982573,0.765758664,,,,,,,, -59,T27D,-0.052200116,-0.017669463,-0.013005533,-1.445405769,-2.29488302,0.05915248,-0.034762106,-0.069638126,-0.036020585,-0.008402157,-0.026936769,-0.017412133,-0.008598933,-0.890592937,-2.0002186,-1.961683246,-2.628082794,2.181692184,1.551446707,,,,,,,, -60,T27G,-0.05851333,0.071181742,-0.028860278,-1.681217301,-2.356711536,-0.01488177,-0.058640051,-0.058386609,-0.078878498,0.081791089,0.060572394,-0.002275716,-0.05544484,-1.386888447,-1.975546154,-2.206922736,-2.506500335,0.772049338,0.719134598,,,,,,,, -61,T27F,-0.046006796,-0.03043394,-0.012103451,-1.582760741,-2.604569889,-0.046856321,-0.045534145,-0.046479447,-0.090757649,-0.023318534,-0.037549346,0.027109167,-0.051316068,-1.183674571,-1.98184691,-2.3495512,-2.859588577,0.969364977,0.766731288,,,,,,,, -62,T27I,0.023747147,0.051240129,0.075382693,0.023093953,-0.280445552,0.004405203,0.002991707,0.044502587,0.054869759,-0.008443589,0.110923846,0.032435341,0.118330044,0.068619705,-0.022431799,-0.213844297,-0.347046807,1.131320058,1.907965161,,,,,,,, -63,T27H,-0.025521534,0.054516839,0.033160455,-0.247634362,-1.849536455,-0.015516528,-0.023085744,-0.027957324,-0.050290329,0.063741083,0.045292595,0.042622928,0.023697982,-0.205396056,-0.289872668,-1.689638244,-2.009434665,1.203319712,1.354291673,,,,,,,, -64,T27K,-0.012258317,0.094588717,0.071384172,-0.694698492,-1.427889436,0.031149431,-0.019092942,-0.005423691,-0.036900614,0.072726807,0.116450626,0.107292716,0.035475628,-0.375580868,-1.013816116,-1.089159826,-1.766619046,1.957469488,1.817070819,,,,,,,, -65,T27M,0.023298222,-0.035811291,-0.049022294,-0.077604075,-1.84309581,-0.029550234,0.010939986,0.035656458,-0.091258277,-0.105851331,0.03422875,-0.057910141,-0.040134447,-0.117289611,-0.037918539,-1.713898763,-1.972292857,1.091363095,1.338692358,,,,,,,, -66,T27L,-0.00520012,0.020403634,0.020395354,-0.002497664,-0.765521147,0.007164919,-0.008171017,-0.002229222,-0.034990466,0.015732065,0.025075202,0.052401689,-0.011610982,0.010565294,-0.015560621,-0.523118342,-1.007923952,0.64180557,1.41243685,,,,,,,, -67,T27N,-0.018373965,0.051236534,0.070673009,-0.567000047,-2.485724922,-0.00692772,-0.004454341,-0.032293589,-0.000322741,0.025715797,0.076757271,0.093086303,0.048259715,-0.245503386,-0.888496708,-2.154058947,-2.817390897,1.21450464,1.303342199,,,,,,,, -68,T27Q,-0.019357507,0.038441852,0.021874675,-0.011546786,-1.667099437,0.007096192,-0.003708771,-0.035006243,-0.03898183,0.021153713,0.055729991,0.003883457,0.039865892,0.012561832,-0.035655404,-1.772080482,-1.562118392,0.638912085,1.305582282,,,,,,,, -69,T27P,-0.012825537,0.040221632,0.03461181,-0.063710394,-1.790172161,0.000370384,-0.0092243,-0.016426774,-0.061390324,0.033592459,0.046850804,0.050711808,0.018511812,-0.05115901,-0.076261777,-1.608203556,-1.972140766,0.830258434,1.32360325,,,,,,,, -70,T27S,0.000828692,0.032511544,0.037237365,0.00384456,-1.392478148,-0.017822742,0.000763483,0.0008939,-0.133810627,-0.000921537,0.065944625,0.065397336,0.009077393,0.047014477,-0.039325358,-1.045130426,-1.73982587,0.705001196,1.351631039,,,,,,,, -71,T27R,-0.040271839,0.013151862,0.052985915,-1.400772418,-2.375093809,0.008316062,-0.013639617,-0.06690406,-0.077932789,-0.008145178,0.034448901,0.052096931,0.053874898,-0.994384024,-1.807160811,-2.093313864,-2.656873754,2.059162141,1.438641087,,,,,,,, -72,T27W,-0.079957782,-0.061488913,-1.224764296,-2.259024869,-2.841700815,-0.050100115,-0.069489008,-0.090426556,-0.176269066,0.021794295,-0.14477212,-0.999039171,-1.45048942,-1.557633469,-2.960416269,-2.748333681,-2.935067949,2.414287908,1.200072427,,,,,,,, -73,T27V,0.017138814,0.054112503,0.024078477,0.023495206,0.034189274,0.026123253,-0.013076521,0.047354148,-0.09869385,0.051003292,0.057221713,0.0518531,-0.003696146,0.04636486,0.000625552,0.068248893,0.000129655,1.000995395,2.750605849,,,,,,,, -74,T27Y,0.054177849,-0.003139565,-1.082915309,-2.411546054,-2.789134768,-0.043960803,0.06320822,0.045147478,-0.1212215,0.014089733,-0.020368863,-0.882236272,-1.283594346,-1.795487707,-3.027604401,-2.576013455,-3.00225608,2.330971542,1.093527199,,,,,,,, -75,L28A,-0.019704669,0.035900647,-0.003939622,0.027649035,-0.20222814,0.008399527,-0.008430686,-0.030978651,0.052565441,0.0017858,0.070015493,-0.022677388,0.014798145,0.040500106,0.014797964,-0.173805337,-0.230650943,1.412477244,2.143914977,,,,,,,, -76,L28C,-0.032813414,-0.047659224,-0.024893669,0.019473818,-1.95959115,0.033836026,-0.009628844,-0.055997983,-0.03776968,-0.081664278,-0.013654169,-0.050404055,0.000616718,0.012688293,0.026259342,-1.363123509,-2.556058791,0.528029817,1.317636037,,,,,,,, -77,L28E,-0.053680802,-0.027822315,0.005018305,0.034194381,-1.721637749,0.062170051,-0.060300458,-0.047061146,0.011197743,-0.039050066,-0.016594563,-0.039229596,0.049266206,0.029358607,0.039030155,-1.548735466,-1.894540031,0.597531518,1.313976786,,,,,,,, -78,L28D,-0.038487142,0.034237114,0.001944002,-1.504097079,-2.71076857,0.048642849,-0.026580588,-0.050393696,0.018490154,-0.004092048,0.072566276,-0.002845629,0.006733633,-1.197068989,-1.811125169,-2.558354537,-2.863182603,0.862907288,0.747605855,,,,,,,, -79,L28G,-0.022334179,-0.03150269,0.003770012,0.03978715,-1.484204085,0.020863209,-0.011678122,-0.032990235,0.053555499,-0.023316038,-0.039689341,-0.035205275,0.042745299,0.012310174,0.067264126,-1.400435145,-1.567973024,0.669484861,1.324566055,,,,,,,, -80,L28F,-0.040002993,-0.070440371,-0.037635603,0.015112183,-0.720047067,-0.038578853,-0.027566088,-0.052439897,0.013702084,-0.041360041,-0.0995207,-0.125446168,0.050174962,-0.019745599,0.049969965,-0.554762104,-0.88533203,1.302795467,1.682510683,,,,,,,, -81,L28I,0.048150386,-0.022671011,-0.003042581,-0.00309151,0.017395788,-0.025860834,0.088786579,0.007514192,-0.05013022,-0.025007759,-0.020334262,-0.05534956,0.049264399,-0.015137646,0.008954627,0.027656387,0.007135189,1.200335453,2.680567088,,,,,,,, -82,L28H,-0.008017467,0.032561265,0.047690945,0.070178796,-0.889277008,-0.008464177,0.01538669,-0.031421623,0.119941152,0.042575509,0.022547021,0.045516028,0.049865861,0.081971662,0.05838593,-0.585200101,-1.193353914,0.397797462,1.360380147,,,,,,,, -83,L28K,-0.005539491,-0.002878644,0.028632088,0.059325622,0.069595673,0.10400271,-0.014369259,0.003290278,-0.052811494,-0.033428372,0.027671084,0.034333273,0.022930902,0.059881153,0.058770091,0.04615663,0.093034716,1.154452356,2.828252916,,,,,,,, -84,L28M,-0.041787101,-0.049764661,0.002258615,-0.00526688,-0.0480697,0.025590638,-0.035141813,-0.048432389,0.110834946,-0.008616484,-0.090912838,-0.008083692,0.012600921,-0.027921639,0.017387879,-0.033204382,-0.062935017,1.214121872,2.476624221,,,,,,,, -85,L28N,-0.035726656,0.023491101,0.015489448,0.05982907,-1.420713538,0.032766648,-0.032235555,-0.039217756,-0.083636957,0.027469676,0.019512526,0.026470652,0.004508243,0.053052553,0.066605587,-1.120972321,-1.720454755,0.648017497,1.341582467,,,,,,,, -86,L28Q,-0.056036688,0.007080485,-0.002020101,0.045650558,-0.222811812,0.034851675,-0.055223318,-0.056850058,0.007987811,0.043285528,-0.029124558,-0.006053269,0.002013067,0.04749584,0.043805275,-0.162915238,-0.282708385,1.299823672,2.151609564,,,,,,,, -87,L28P,-0.007785697,0.004923397,-0.015633364,-0.897614543,-2.195354681,0.002928139,0.007419172,-0.022990565,0.046125877,-0.041566146,0.051412939,-0.071990234,0.040723506,-0.482904325,-1.31232476,-2.039768688,-2.350940673,1.648785424,1.376264368,,,,,,,, -88,L28S,-0.030663797,-0.019146217,-0.035706727,-0.007251027,-1.264096226,0.024712166,-0.02469844,-0.036629154,0.057383265,-0.054752904,0.01646047,-0.083555676,0.012142222,-0.047995151,0.033493098,-1.073604209,-1.454588243,0.973728461,1.391577557,,,,,,,, -89,L28R,-0.01000016,-0.012317896,0.000608244,0.011852271,-0.064935717,-0.002833226,-0.011642725,-0.008357594,0.016334951,-0.017567512,-0.00706828,-0.021453703,0.022670191,0.008084394,0.015620147,-0.063067001,-0.066804433,1.236790042,2.283846378,,,,,,,, -90,L28T,-0.001606327,0.014496056,0.001228926,0.003866305,-0.313656419,-0.009803708,-0.009859284,0.00664663,0.048529661,-0.002247418,0.031239529,-0.021174839,0.023632691,-0.006817963,0.014550572,-0.246602654,-0.380710184,1.431270149,2.048091072,,,,,,,, -91,L28W,-0.024043175,-0.053305583,-0.024093091,-0.005568072,-0.299738494,-0.053695544,0.000671163,-0.048757513,0.115608145,-0.108664755,0.002053589,-0.103328715,0.055142534,-0.071816898,0.060680754,-0.276355435,-0.323121552,1.739425948,2.24294914,,,,,,,, -92,L28V,-0.011099186,0.005321875,-0.010107739,0.033466369,0.0502655,0.00649983,-0.027822718,0.005624347,0.113093607,-0.017248663,0.027892412,-0.037449251,0.017233773,0.011705326,0.055227411,0.070190045,0.030340954,1.179595765,2.85762827,,,,,,,, -93,L28Y,-0.013498753,0.02340398,0.037875386,0.049471904,-0.218600359,0.053112228,0.025243258,-0.052240763,-0.004014579,0.024484456,0.022323503,0.001705658,0.074045114,0.075707921,0.023235887,-0.143416948,-0.29378377,1.260382411,2.154641454,,,,,,,, -94,V29A,0.03161015,-0.001833615,0.053258459,0.056550645,0.046784508,0.023513221,0.019564078,0.043656221,-0.005949811,-0.006176664,0.002509434,0.050462148,0.056054769,0.001218389,0.111882901,0.067174145,0.026394871,1.093890742,2.765416111,,,,,,,, -95,V29C,0.051793601,0.056978618,0.098457681,0.100557742,0.035059494,0.020501593,0.065131136,0.038456065,0.062122526,0.033926363,0.080030872,0.036764281,0.16015108,0.085099194,0.116016289,-0.001241264,0.071360251,1.147656284,2.672187365,,,,,,,, -96,V29E,-0.076401493,-0.004996111,0.00256741,0.06816767,0.05100108,-0.006401378,-0.076764329,-0.076038656,-0.052261461,0.077038756,-0.087030977,0.051682473,-0.046547653,0.079700688,0.056634652,0.162227967,-0.060225808,1.097267627,3.14722183,,,,,,,, -97,V29D,0.123781935,0.020589661,0.051152648,0.070239921,0.044413266,-0.019608718,0.082869227,0.164694643,-0.005051826,-0.030161045,0.071340367,-0.008918065,0.11122336,-0.063354554,0.203834396,0.066713924,0.022112608,1.068447199,2.736890459,,,,,,,, -98,V29G,-0.000823415,0.013215538,0.033055424,0.040087412,0.040152735,0.013481811,-0.009105045,0.007458215,-0.020173158,0.017056911,0.009374165,0.037141808,0.02896904,-0.005990934,0.086165758,0.053927577,0.026377893,1.076833718,2.62284945,,,,,,,, -99,V29F,0.052479281,0.01863507,0.064025484,0.103727905,-0.060232139,-0.021254013,0.048621732,0.05633683,-0.041556477,-0.021618786,0.058888926,0.045415392,0.082635575,-0.015414473,0.222870283,-0.050873122,-0.069591156,1.236356625,2.385207366,,,,,,,, -100,V29I,-0.050772924,0.02059818,-0.036868409,0.062718591,-0.013303234,-0.072786189,-0.048780545,-0.052765302,-0.062777579,-0.004606941,0.0458033,-0.040687089,-0.033049729,-0.006910895,0.132348077,-0.005603878,-0.02100259,1.250835485,2.621054217,,,,,,,, -101,V29H,-0.014345747,0.024843938,0.046788516,0.017439621,-0.014840417,-0.036869974,-0.039654776,0.010963282,-0.034660366,0.036259943,0.013427932,0.032056213,0.061520819,-0.007805357,0.042684599,0.00354753,-0.033228364,1.148125972,2.50576595,,,,,,,, -102,V29K,-0.015901929,-0.021431138,0.034864865,0.030639455,0.036194098,-0.053390969,0.017719448,-0.049523305,-0.073212986,0.093542145,-0.136404421,0.063909753,0.005819976,0.054965492,0.006313417,0.098211758,-0.025823563,1.680490028,3.618873133,,,,,,,, -103,V29M,0.17816574,0.054498452,0.123752892,0.182864283,0.096017091,-0.101066501,0.20472521,0.151606269,-0.062985326,0.048314605,0.060682299,0.02413368,0.223372104,0.067199949,0.298528616,0.077986487,0.114047695,1.062435116,2.89406119,,,,,,,, -104,V29L,-0.000693695,0.011406346,0.031761116,0.039559515,-0.01214075,-0.044949337,0.006982885,-0.008370274,-0.007272999,0.026452778,-0.003640087,0.060232925,0.003289307,0.011039334,0.068079695,0.025135912,-0.049417411,1.299873983,2.842602897,,,,,,,, -105,V29N,0.027439061,-0.027357327,0.014343378,0.065510499,0.051505843,-0.122263696,-0.024110671,0.078988792,-0.003789621,0.022812259,-0.077526913,0.003826408,0.024860347,-0.003942495,0.134963493,0.003093174,0.099918511,1.351575961,2.679081423,,,,,,,, -106,V29Q,-0.02712337,0.006014605,0.042593005,0.026620047,0.021601685,-0.071417555,-0.04498626,-0.009260479,-0.072969547,0.008806063,0.003223147,0.072550667,0.012635343,0.022296376,0.030943717,0.021949461,0.021253908,1.14065731,2.699438039,,,,,,,, -107,V29P,-0.005682703,0.006407447,0.043631888,-1.316034756,-2.3870484,-0.04179938,0.001345294,-0.0127107,-0.039839861,-0.00096412,0.013779014,0.042776875,0.044486901,-0.872145464,-1.759924048,-2.311736352,-2.462360447,1.867994284,1.312881145,,,,,,,, -108,V29S,0.008664827,0.035151562,0.061598774,0.07835551,0.008377766,-0.045833511,-0.019010396,0.036340049,-0.043936072,0.035392973,0.034910151,0.076166795,0.047030752,0.049495354,0.107215666,0.033026829,-0.016271297,1.239467195,2.880565512,,,,,,,, -109,V29R,0.007714585,-0.00501381,0.023897913,0.041116586,0.065185473,0.070105522,-0.000358616,0.015787786,-0.049437077,-0.014894056,0.004866436,0.011441043,0.036354782,-0.012543149,0.09477632,0.066319154,0.064051791,1.097271519,2.848419622,,,,,,,, -110,V29T,0.021507369,0.05291894,0.040859774,0.055199141,0.029703033,-0.051098656,-0.011330593,0.05434533,-0.089681912,0.041579133,0.064258746,0.076970068,0.004749479,0.030212669,0.080185612,0.059472965,-0.0000669,1.57943243,3.568681248,,,,,,,, -111,V29W,0.078299356,0.010157491,0.059404704,0.038858458,0.056414715,0.051696306,0.076785755,0.079812956,-0.193038778,-0.02650755,0.046822532,0.03300026,0.085809147,-0.044092725,0.12180964,0.039520486,0.073308943,1.182111691,2.640051708,,,,,,,, -112,V29Y,0.013139012,-0.052346871,0.060791209,0.073165579,-0.087401776,-0.092002091,-0.005883819,0.032161843,0.032545243,-0.05719558,-0.047498161,0.035042749,0.086539668,0.020811216,0.125519941,-0.051187616,-0.123615936,1.239348798,2.512211098,,,,,,,, -113,K30A,0.098663776,0.001876084,0.021097675,0.007989488,0.000581568,-0.111935875,0.108051275,0.089276277,0.125844321,0.009095029,-0.005342861,-0.054948823,0.097144172,-0.031863578,0.047842554,0.026443098,-0.025279963,1.215440898,2.643618685,0.837905779,0.628528618,1.042039902,1.498758507,-0.29369117,1.313893036,0.913275514,0.075666693 -114,K30C,0.033087664,-0.010271906,-0.019295232,-0.00294336,-1.580349542,-0.046436457,0.074102922,-0.007927595,0.150253112,0.040484573,-0.061028385,-0.03066882,-0.007921644,0.009360302,-0.015247022,-1.301597083,-1.859102,0.854706944,1.348014256,-5.779736073,-5.479257507,-4.939407799,-6.313172951,-6.810970337,-5.355871773,-6.583297117,-8.337572183 -115,K30E,0.007424357,-0.015315282,-0.036557396,-0.330340993,-1.653192955,-0.136973904,0.0111703,0.003678414,0.019338955,0.007837029,-0.038467593,-0.092635858,0.019521066,-0.169878032,-0.490803953,-1.450872194,-1.855513715,1.226917983,1.389399291,-0.822345796,-1.697077957,-0.743323082,-0.380125427,-1.323093552,0.031891037,-1.271839753,0.317896481 -116,K30D,0.008336566,-0.03788243,-0.022883766,-1.317452862,-2.167242514,-0.121515065,0.014474142,0.00219899,0.104033535,-0.015772561,-0.059992299,-0.098420604,0.052653073,-0.766639906,-1.868265817,-2.384056039,-1.950428989,1.776104983,1.281450133,-2.418209932,-3.253353249,-2.096512154,-2.774565056,-2.335383934,-1.631235268,-1.999629703,-0.90221522 -117,K30G,0.033980705,-0.004905307,0.010699258,-0.812287217,-2.15303464,-0.101360972,0.054263426,0.013697984,0.115023105,0.025310383,-0.035120997,-0.070186779,0.091585294,-0.461051681,-1.163522753,-2.047418377,-2.258650902,1.626647493,1.365891776,-3.194096709,-3.447734337,-2.414639771,-3.092382713,-4.168910072,-2.84681665,-2.244031052,-2.46368263 -118,K30F,0.027638142,0.008010398,0.000119235,-0.014441951,-2.087469761,-0.186184963,0.009736959,0.045539325,0.098707741,0.019713267,-0.003692472,-0.089997059,0.090235528,-0.081700587,0.052816685,-2.374815382,-1.80012414,0.799276741,1.255140555,-6.344206351,-6.175813385,-4.970588928,-8.025809296,-7.446648804,-5.102171341,-5.849842117,-6.411706676 -119,K30I,0.010255164,-0.091325398,-0.035397017,-0.043075066,-0.404046646,-0.103629511,0.02578875,-0.005278422,-0.001295206,0.010289788,-0.192940584,-0.026168319,-0.044625715,-0.005221698,-0.080928434,-0.154915453,-0.653177838,1.409776338,2.211424761,-4.334541829,-4.509805832,-3.477678177,-4.521782112,-5.02389769,-4.139545334,-5.178339887,-5.233728922 -120,K30H,0.068215426,0.009651037,-0.017634302,0.011489618,-0.866930596,-0.125393622,0.103890507,0.032540345,0.143245938,-0.002925575,0.022227649,-0.09891257,0.063643967,-0.040180572,0.063159808,-0.612208157,-1.121653035,1.173167464,1.570426847,-3.719487274,-4.27606691,-2.605091286,-4.27651622,-4.635035751,-2.804726204,-2.424629756,-2.585755571 -121,K30M,0.062277793,0.023867304,0.059620796,0.034297133,-0.205193373,-0.167566206,0.077750317,0.046805268,0.053903535,0.114473303,-0.066738695,0.031657772,0.08758382,0.030775956,0.037818309,-0.149276376,-0.26111037,1.159116453,2.042228699,-3.241420384,-3.616566727,-3.095415916,-3.176568008,-4.014547333,-2.304003937,-3.053468105,-3.737739976 -122,K30L,0.060868552,-0.002755927,0.012091929,0.00917773,-0.302453322,-0.163733151,0.070470193,0.051266911,0.097357835,0.020039192,-0.025551045,-0.032931954,0.057115811,-0.037604624,0.055960083,-0.241213408,-0.363693236,1.546319059,2.119093586,-4.155451071,-4.41808667,-3.955308891,-4.298294556,-4.726511543,-3.379053696,-3.872068358,-4.281316547 -123,K30N,0.054542541,-0.007118245,-0.039191699,-0.060147347,-1.532004423,-0.205663956,0.06252315,0.046561932,0.104398949,-0.042242686,0.028006196,-0.176746939,0.098363542,-0.091904051,-0.028390643,-1.789549186,-1.27445966,0.844026608,1.313565448,-2.32740654,-2.536827377,-1.41341291,-2.683565102,-2.672767746,-2.330459564,-2.328610533,-1.929901572 -124,K30Q,0.056873917,-0.002156619,0.029907995,0.04242421,-0.093847677,-0.025276082,0.062291927,0.051455907,0.057852549,-0.000235326,-0.004077912,-0.047559457,0.107375447,-0.046455275,0.131303694,-0.110687913,-0.07700744,1.5520766,2.43852726,-0.281667992,-0.786543053,0.224413094,-0.19232415,-1.033077347,0.379191498,-0.059245162,0.187540596 -125,K30P,0.056774197,0.011558656,-0.645166878,-2.126830294,-2.525360861,-0.126639626,0.085055976,0.028492417,0.093745909,-0.00623241,0.029349722,-0.492631505,-0.79770225,-1.938340705,-2.315319882,-2.260975792,-2.78974593,1.632231149,0.752570757,-2.89878623,-2.082377243,-2.280247513,-3.102823738,-3.881271591,-3.147211067,-2.516458093,-2.953931396 -126,K30S,0.046516324,0.021456691,0.00890171,0.006854943,-0.378632472,-0.104351022,0.060770968,0.032261679,0.128239908,0.072688719,-0.029775338,-0.043260302,0.061063722,-0.013390882,0.027100768,-0.293573253,-0.46369169,1.031033586,1.706710806,-0.555635321,-0.202871422,-0.09264872,-0.480241135,-1.748080048,-0.254335281,-0.942116066,-1.11555736 -127,K30R,0.03564085,0.018416099,0.02329738,0.004958871,-0.006089577,-0.101736269,0.05223952,0.019042179,0.100842886,0.037430635,-0.000598438,-0.019590624,0.066185383,-0.012652427,0.022570168,0.038253263,-0.050432417,1.261967274,2.856004044,-0.398836171,-0.79846949,-0.070430267,-0.513058411,-1.214217468,0.601994781,-1.365970825,0.587392949 -128,K30T,0.074175399,0.037650626,0.049637736,0.029346545,-0.041735782,-0.024353211,0.120284119,0.028066678,0.101117004,0.055799039,0.019502212,-0.038494157,0.137769628,-0.006737561,0.065430651,-0.058770113,-0.02470145,1.301148956,2.37562884,1.493426451,1.920127396,1.587223045,1.783307762,0.349395699,1.827078354,0.097393067,-0.8518234 -129,K30W,0.050561882,-0.004388008,-0.015592951,-0.84836765,-2.032560763,-0.128216571,0.076736853,0.024386911,0.100389621,0.020688283,-0.029464298,-0.098291905,0.067106003,-0.449875809,-1.24685949,-2.311228222,-1.753893304,1.608362532,1.320402571,-6.315228481,-6.152644569,-5.020183746,-7.288060196,-7.543967766,-5.571286125,-6.208597163,-6.843326166 -130,K30V,0.062050953,-0.029194402,-0.006741151,-0.009877641,-0.06138358,-0.096197487,0.087093291,0.037008615,0.114958976,0.004882258,-0.063271062,-0.053612636,0.040130334,-0.031999633,0.012244352,-0.011318385,-0.111448775,1.238995107,2.553759515,-3.035197964,-3.448182083,-2.42438118,-2.959265999,-3.792495995,-2.551664566,-3.504808273,-3.835945057 -131,K30Y,-0.032652425,-0.070249077,-0.064128776,-0.101631774,-2.123162699,-0.225698808,-0.01108261,-0.05422224,0.071096854,-0.03064554,-0.109852614,-0.101457641,-0.02679991,-0.096910013,-0.106353534,-1.718086295,-2.528239102,0.63880243,1.307750691,-5.676549431,-5.240430244,-4.175158318,-7.222781235,-6.810007614,-4.934369743,-4.597604732,-4.786747119 -132,V31A,-0.075996644,-0.02437406,0.000986701,-0.032705785,-1.100230314,-0.007892398,-0.086073708,-0.06591958,-0.013371739,-0.059693578,0.010945458,-0.015030922,0.017004324,-0.043814634,-0.021596935,-0.712576149,-1.487884479,0.772407659,1.408657638,-2.562999887,-2.539596916,-2.873806938,-1.16427105,-2.694993637,-3.542330894,-3.029527824,-2.046100846 -133,V31C,-0.065796181,-0.054665922,-0.03560006,-0.080138818,-0.095361794,0.042011734,-0.112345395,-0.019246966,0.024096819,-0.062756371,-0.046575472,-0.070579737,-0.000620383,-0.083053664,-0.077223972,-0.06745872,-0.123264867,1.293950139,2.259710242,-7.620479198,-7.680981247,-7.131140785,-6.71985659,-8.352412468,-8.218004898,-4.860159266,-3.947978623 -134,V31E,-0.048830646,-0.989157572,-2.365067413,-3.050932108,-2.976464559,-0.032285376,-0.014184621,-0.08347667,0.083833286,-0.677285147,-1.301029996,-2.461660864,-2.268473962,-2.873635008,-3.228229208,-2.672047362,-3.280881755,0.198915878,-0.562142554,-9.085897371,-9.482632393,-9.161206879,-8.324126488,-9.184479668,-9.277041428,-8.241014407,-8.525554921 -135,V31D,0.032329615,-0.71383255,-1.948469096,-2.322709146,-3.147911871,0.009214029,0.074801808,-0.010142578,-0.03480903,-0.553759007,-0.873906093,-2.127674563,-1.769263629,-2.363557448,-2.281860844,-3.116212311,-3.179611431,1.109715007,-0.284615183,-9.560686906,-10.10386174,-9.511571793,-9.017572029,-9.527042084,-9.643386887,-8.241014407,-8.525554921 -136,V31G,-0.062077347,-0.01700883,-0.964319232,-2.284034961,-3.019922186,0.031486572,-0.04441844,-0.079736253,-0.034541572,-0.039048788,0.005031129,-0.632927667,-1.295710797,-2.20009978,-2.367970141,-2.972958029,-3.066886342,1.643490778,0.647165082,-8.657687073,-9.237576248,-8.62345874,-7.848344597,-8.704456032,-8.874599747,-8.241014407,-8.525554921 -137,V31F,-0.044471795,-0.039700708,-0.56179174,-1.806706091,-2.899465416,-0.051352928,-0.039598546,-0.049345044,-0.071258394,-0.045363463,-0.034037952,-0.361957951,-0.761625528,-1.773932094,-1.839480087,-3.003708212,-2.79522262,1.526848631,0.772933851,-7.436471581,-7.018656029,-7.112294006,-6.463050133,-8.95459169,-7.633766045,-3.870201435,0.400074225 -138,V31I,0.044659067,0.00942231,0.036875603,-0.019516789,-0.051860533,-0.062706794,0.045303247,0.044014886,0.027440762,0.023777846,-0.004933226,-0.020128488,0.093879694,-0.023977696,-0.015055882,-0.044985101,-0.058735965,1.213343559,2.398956387,-0.435060857,-0.123762497,-0.969246185,-0.809789818,-0.50168174,0.229175957,-1.516464323,1.216243917 -139,V31H,-0.103879166,-0.362949439,-2.058749347,-2.273232696,-3.399465416,-0.025588131,-0.094096552,-0.113661779,0.078606024,-0.211558013,-0.514340865,-2.219290447,-1.898208246,-2.18410656,-2.362358832,-3.304738208,-3.494192624,0.300205071,-0.386077794,-11.02338548,-10.33589017,-11.29593047,-10.20894553,-11.56431229,-11.71184893,-8.241014407,-8.525554921 -140,V31K,-0.069959217,-1.025541657,-2.282289191,-2.238457642,-2.791626345,-0.015471355,-0.056984189,-0.082934244,0.020253137,-0.701422558,-1.349660755,-2.729734554,-1.834843827,-2.238618711,-2.238296573,-2.639091056,-2.944161633,0.380747902,-0.558198513,-9.626291118,-10.31131435,-9.45243634,-8.79461573,-9.529177353,-10.04391182,-8.241014407,-8.525554921 -141,V31M,-0.041561628,-0.007445106,-0.019076704,-0.002869713,-1.553265428,-0.044758175,-0.077024889,-0.006098366,-0.080091179,-0.038053519,0.023163308,-0.041572092,0.003418684,-0.021768302,0.016028877,-1.350907547,-1.755623308,0.803002848,1.339782133,-4.757160342,-4.471318558,-4.517368561,-4.742915482,-5.079248596,-4.974950516,-3.298961354,-1.560200634 -142,V31L,-0.031101205,-0.036818768,-0.00173694,-0.031376676,-0.088425787,-0.048389108,-0.053680381,-0.008522028,0.013463985,-0.027364741,-0.046272794,-0.024077422,0.020603543,-0.033727436,-0.029025915,-0.060220939,-0.116630635,1.240399902,2.312975351,-2.326860617,-2.352951843,-1.005902313,-2.903250206,-2.960371796,-2.411826927,-1.858307684,1.443182849 -143,V31N,-0.075028066,-0.024041029,-1.09737067,-2.345433129,-2.859011209,-0.045339542,-0.094956601,-0.05509953,0.016846616,-0.051617024,0.003534966,-0.794723453,-1.400017886,-2.437146518,-2.25371974,-2.888771385,-2.829251032,1.097612071,0.255277946,-9.883094162,-10.60920161,-10.56843042,-9.054346039,-9.737616142,-9.445876595,-8.241014407,-8.525554921 -144,V31Q,-0.059804751,-0.625650008,-2.061013374,-2.629836465,-3.006913909,0.027160731,-0.055417799,-0.064191702,0.033721492,-0.477985203,-0.773314812,-2.194363841,-1.927662906,-2.305307988,-2.954364942,-2.705780333,-3.308047484,0.487568376,-0.459309165,-9.394928345,-10.14651067,-9.274348022,-8.670092072,-9.271468185,-9.612222771,-8.241014407,-8.525554921 -145,V31P,-0.042273958,-0.751933821,-1.770383745,-2.196451302,-3.137351061,-0.044176823,-0.0223778,-0.062170116,0.022724204,-0.559265681,-0.94460196,-1.804463007,-1.736304482,-1.973399102,-2.419503502,-2.741848232,-3.532853889,3.117013314,1.265685669,-8.989638065,-9.740840668,-8.963133873,-8.168106186,-9.034269844,-9.041839752,-8.241014407,-8.525554921 -146,V31S,-0.047669584,-0.008726814,-0.120025718,-1.666378845,-2.725262278,-0.046619187,-0.045684266,-0.049654902,-0.034127558,-0.054309917,0.03685629,-0.09015321,-0.149898225,-1.30093041,-2.031827279,-2.462954743,-2.987569813,1.084960804,0.771125865,-7.989450751,-8.354382401,-8.490204788,-6.909585564,-8.006886345,-8.186194656,-7.817359495,-6.92075765 -147,V31R,-0.059580569,-0.717611195,-1.875773689,-2.483971873,-3.148064951,-0.008960364,-0.050560348,-0.068600789,0.0292554,-0.507528423,-0.927693966,-1.946623155,-1.804924223,-2.160229645,-2.807714101,-3.009794521,-3.28633538,1.406323118,-0.058265894,-9.708960872,-10.47475101,-9.511413002,-9.10216449,-9.478334061,-9.9781418,-8.241014407,-8.525554921 -148,V31T,-0.045244166,-0.007692451,0.002721587,-0.049525107,-1.944226231,-0.018735602,-0.036194725,-0.054293607,-0.026824569,-0.016471562,0.00108666,-0.0195937,0.025036873,-0.061203933,-0.03784628,-1.882740085,-2.005712376,0.918187608,1.311526999,-6.235697949,-6.894956497,-6.409180824,-5.043300819,-5.959005341,-6.872046265,-6.235958592,-4.671766847 -149,V31W,-0.02646088,-0.02298481,-0.921336601,-2.366458266,-2.890630995,-0.020001108,-0.01724748,-0.035674279,-0.037005403,-0.007281058,-0.038688562,-0.615422444,-1.227250757,-2.369819268,-2.363097263,-2.821444136,-2.959817854,1.103884317,0.327111541,-9.187465666,-8.899790344,-8.154858109,-8.157319115,-10.84349556,-9.881865204,-4.838212225,-3.17142041 -150,V31Y,-0.104011732,-0.820416339,-2.471041066,-2.705360768,-2.670483841,-0.045836411,-0.087077279,-0.120946185,-0.027037859,-0.516339142,-1.124493535,-2.373023377,-2.569058755,-2.784997521,-2.625724015,-2.759501134,-2.581466548,0.418124624,-0.487804811,-11.43196246,-10.05513752,-12.14379382,-10.38564597,-12.3709891,-12.20424586,-5.306024199,-3.811571927 -151,K32A,-0.015604664,0.019891445,0.007808409,0.008947247,0.054800478,-0.002158839,-0.012115308,-0.019094019,-0.007887097,0.073827632,-0.034044743,0.00126584,0.014350978,0.008419326,0.009475167,0.073109985,0.03649097,1.062880444,2.728188479,-1.321693956,-2.873778427,-0.325176743,-3.460142937,0.602401222,-0.551772896,-3.683966882,1.152396283 -152,K32C,-0.039695645,-0.027003285,-0.021839165,-0.000174733,-0.969015678,-0.01477086,-0.042939199,-0.036452091,0.021777464,0.06820574,-0.12221231,-0.026254053,-0.017424276,-0.025397414,0.025047948,-0.66856635,-1.269465005,0.840692518,1.438080262,-6.083610005,-7.131878113,-5.697205795,-8.132425163,-4.466801422,-4.989739532,-6.369513465,-4.008096216 -153,K32E,-0.066786435,0.011041277,-0.017254346,0.000382647,-0.144527081,0.022663684,-0.095066284,-0.038506585,0.03718057,0.07807411,-0.055991556,0.04693887,-0.081447561,0.000037,0.000728293,-0.056360561,-0.2326936,1.334963185,2.547394554,-1.336587537,-1.480103409,-0.919144981,-2.095445999,-0.887650673,-1.300592621,-2.066542786,0.471515256 -154,K32D,-0.080591094,-0.022217113,-0.023182696,-0.078947048,-2.334892706,0.023070007,-0.07809347,-0.083088718,-0.036603018,0.044819952,-0.089254178,-0.126535997,0.080170606,-0.073379107,-0.084514988,-1.855353397,-2.814432014,0.941837523,1.315331444,-2.756284123,-2.751747292,-2.296906914,-4.092553085,-1.976085457,-2.664127869,-3.786602979,-0.461252834 -155,K32G,-0.068605018,-0.000238825,-0.015770798,0.004542492,-0.282379712,0.004978116,-0.091306135,-0.0459039,-0.045278386,0.087542021,-0.088019671,0.015913418,-0.047455013,0.027912556,-0.018827573,-0.225527198,-0.339232225,1.059827846,1.810152875,-3.628366774,-4.454512512,-3.05998925,-5.580658829,-2.302362785,-2.744310493,-3.476903979,-1.338100196 -156,K32F,-0.034970701,0.069830428,0.002291099,0.047763703,-0.594552833,0.040633457,-0.040622757,-0.029318644,0.010545084,0.128267214,0.011393641,-0.011360807,0.015943005,0.061628345,0.033899061,-0.464260915,-0.72484475,0.532288253,1.408297057,-5.196635941,-5.838807655,-4.962921188,-6.945696899,-3.52518586,-4.7105681,-5.25442034,-2.765570382 -157,K32I,-0.053923187,-0.006977377,0.014303943,-0.00935546,-0.017447561,0.002433742,-0.073641634,-0.034204739,-0.07640196,0.076829591,-0.090784344,-0.023575119,0.052183005,0.046972401,-0.065683321,-0.01458913,-0.020305992,1.244701655,2.497998054,-3.662684059,-4.460034546,-3.291589302,-5.295749451,-2.232616852,-3.033430145,-3.898592622,-2.253665501 -158,K32H,-0.052013552,0.009416246,-0.016035267,0.008534208,0.006558769,0.008257579,-0.066639252,-0.037387851,-0.067018725,0.11406514,-0.095232649,0.009189445,-0.041259979,0.06273718,-0.045668765,0.042587079,-0.029469541,1.301710207,3.17062907,-3.398539857,-3.512382378,-3.069107025,-4.121965744,-2.393845512,-3.895398628,-4.24838776,-1.83329151 -159,K32M,0.015388874,0.065400621,0.003718816,0.023057327,-0.0038691,0.008279769,0.00998322,0.020794528,0.041552823,0.104038559,0.026762682,-0.014190239,0.021627871,0.036970492,0.009144161,-0.027968929,0.020230729,1.213061959,2.521449409,-4.37464368,-5.088653,-4.376490677,-6.1072882,-2.676566788,-3.624219734,-4.874484142,-2.792572305 -160,K32L,-0.048355687,-0.007040698,-0.009700128,-0.001780173,-0.075988297,0.024515292,-0.054544411,-0.042166963,-0.006754505,0.046311446,-0.060392841,-0.038804323,0.019404067,-0.015385394,0.011825049,-0.062223224,-0.089753369,1.521587861,2.602421961,-3.921579474,-4.823204071,-3.89752195,-5.799933281,-2.018369194,-3.068868874,-4.659920044,-1.885810279 -161,K32N,-0.065733575,0.006450168,0.007732263,-0.015648105,-0.194365353,-0.024103531,-0.085297005,-0.046170144,-0.145618789,0.048481059,-0.035580723,-0.029665633,0.045130159,0.003637182,-0.034933392,-0.221200039,-0.167530667,1.436897644,2.132181688,-2.976704341,-2.984287933,-2.06628096,-4.964504921,-2.252551514,-2.615896378,-4.431956099,-0.928379166 -162,K32Q,-0.010354301,0.092674519,0.043778557,0.003481532,0.122206575,0.012338793,-0.018077528,-0.002631073,-0.061379087,0.157073639,0.028275399,0.046556586,0.041000527,0.059868973,-0.05290591,0.152671443,0.091741707,1.053747927,2.964747425,-0.619891478,-0.156779282,-0.599383553,-0.834075348,-0.604265289,-0.904953918,-1.755941358,0.090153151 -163,K32P,-0.028991613,-0.351435392,-1.809724675,-2.19368559,-2.976554563,0.001891771,-0.024130227,-0.033852999,-0.035815658,-0.086091454,-0.616779329,-1.741367005,-1.878082345,-2.124869383,-2.262501796,-2.527585878,-3.425523248,0.693306826,-0.028133734,-6.657078404,-7.732863327,-6.031923248,-8.566618767,-4.817249985,-6.136736694,-6.129094091,-4.504052758 -164,K32S,-0.033017345,-0.018210197,-0.024197018,-0.008787721,-0.177984501,-0.025022237,-0.053070999,-0.01296369,0.005381998,0.044375092,-0.080795485,-0.041040235,-0.007353801,0.001399416,-0.018974858,-0.154427826,-0.201541175,1.502444811,2.281921444,-2.116253867,-2.824833984,-1.070628044,-4.806527718,-0.3950298,-1.484249786,-3.140940173,-0.380998387 -165,K32R,-0.031927773,-0.007760311,-0.006062351,-0.017886342,0.068602495,-0.003459301,-0.046083975,-0.017771571,-0.074888896,0.073190418,-0.08871104,-0.016200362,0.004075661,0.000206862,-0.035979545,0.084487896,0.052717093,1.065808838,2.775893169,-0.591184605,-0.718717857,-0.752425873,-0.440273972,0.041881699,-1.086387024,-1.839197277,0.57278973 -166,K32T,0.005153951,0.043806982,0.009874979,0.023930992,-0.146127025,0.012004618,0.012910034,-0.002602132,-0.089879385,0.086448418,0.001165545,-0.003040686,0.022790644,0.032783392,0.015078591,-0.116207507,-0.176046543,1.366388695,2.31651611,-2.524708043,-3.243774834,-1.709476906,-5.142050323,-0.879074562,-1.649163589,-2.791133663,-0.635363317 -167,K32W,-0.115837923,-0.000877116,0.03673846,0.024794749,-0.240520849,0.021712977,-0.06475629,-0.166919555,-0.092079997,0.085441653,-0.087195884,0.088385683,-0.014908763,0.105930876,-0.056341378,-0.155081588,-0.32596011,1.139721197,2.093516731,-7.769459604,-8.513265221,-7.538756424,-9.038483429,-6.401240295,-7.35555265,-8.401911781,-7.454458271 -168,K32V,-0.004279184,0.030147444,-0.011977426,-0.005510322,-0.073791384,-0.024232961,-0.017410486,0.008852118,-0.040961781,0.084598887,-0.024303999,-0.026975888,0.003021036,0.003405258,-0.014425902,-0.035733414,-0.111849354,1.231212902,2.463677436,-3.437167526,-4.452638763,-3.113702515,-5.106428062,-1.66657811,-2.846490181,-3.929580453,-1.68344417 -169,K32Y,-0.030621018,0.01379667,0.026521195,0.016163334,-0.35842172,0.003269877,-0.014282456,-0.04695958,-0.000681246,0.087826791,-0.060233451,-0.011059388,0.064101778,0.014659254,0.017667414,-0.237644813,-0.479198627,1.632950097,2.26484178,-5.756456578,-6.089122345,-5.542023712,-7.307602081,-4.295888893,-5.547645859,-5.698332763,-3.381149621 -170,D33A,0.028067865,-0.04812054,-0.022572998,-0.040386565,-0.005625546,0.008648798,-0.016807806,0.072943535,-0.096200525,-0.122812759,0.026571679,-0.08438582,0.039239825,-0.050254634,-0.030518496,-0.008656962,-0.00259413,1.070070397,2.497707602,0.80247679,0.328408989,1.05194574,0.841936539,0.757934311,1.032158371,-0.924662169,1.147866771 -171,D33C,0.008000925,-0.085715771,-0.040377672,-0.08298181,-0.143159049,0.046908974,-0.02011385,0.0361157,-0.076739729,-0.116343101,-0.055088441,-0.066729522,-0.014025822,-0.059129575,-0.106834044,-0.103644393,-0.182673705,1.342869861,2.260455052,-5.647521811,-5.762804611,-5.125831451,-6.190252335,-5.782899841,-5.375820816,-6.730293744,-7.812815001 -172,D33E,-0.030137327,-0.079703765,-0.004627208,-0.06942323,-0.038181221,0.002398536,-0.039935291,-0.020339363,-0.055894417,-0.096937764,-0.062469766,-0.020479725,0.011225309,-0.102862517,-0.035983943,-0.022735049,-0.053627393,1.14559757,2.243716485,0.912113791,0.393348183,0.814259315,0.965996552,1.211355804,1.1756091,0.168026208,0.749457736 -173,D33G,-0.033577053,-0.123070613,-0.056711856,-0.070387108,-0.164200601,-0.039234579,-0.083108335,0.015954229,-0.068662434,-0.13273454,-0.113406686,-0.088232638,-0.025191073,-0.049863522,-0.090910693,-0.130331409,-0.198069792,1.503541187,2.317370164,-1.195077411,-0.713576637,-0.989069351,-1.489844879,-1.312773933,-1.470122253,-1.849383724,-0.808506736 -174,D33F,0.008737043,-0.014125427,-0.002050294,-0.065057898,-0.244432783,-0.072733668,-0.036603409,0.054077494,-0.036864066,-0.080025947,0.051775094,-0.059205725,0.055105138,-0.029565896,-0.1005499,-0.224665409,-0.264200156,1.590887955,2.182387887,-4.399182268,-4.395158623,-4.629882545,-4.269723618,-4.389423401,-4.311723152,-4.83881443,-3.900884128 -175,D33I,-0.003618043,-0.055324998,-0.045078097,-0.041143382,-0.137432674,-0.081726703,-0.020178281,0.012942195,-0.024797579,-0.080330471,-0.030319525,-0.04826706,-0.041889133,-0.007796949,-0.074489814,-0.080451743,-0.194413604,1.568759957,2.584738296,-2.570039449,-2.824345741,-2.016215172,-2.479498581,-2.770048676,-2.760089073,-3.592929923,-2.720193299 -176,D33H,0.018694363,-0.03809453,-0.00484842,-0.046429917,-0.043367243,0.002459112,-0.027099971,0.064488696,0.005070412,-0.098402151,0.022213092,-0.049485363,0.039788523,-0.05421804,-0.038641794,-0.068558274,-0.018176211,1.467867817,2.449785519,-2.114678854,-1.714464752,-2.737026985,-2.686160736,-1.742855713,-1.692886086,-2.452988378,-1.822084611 -177,D33K,-0.017405218,-0.086614501,-0.054365791,-0.080006361,-0.046872657,0.01170058,-0.051793864,0.016983429,-0.114247486,-0.208207014,0.034978013,-0.162018852,0.05328727,-0.044059946,-0.115952776,-0.05282474,-0.040920573,1.298172133,2.38351553,-0.014223093,0.208455696,-0.243836731,-0.094591217,0.43496434,-0.376107552,-0.965441355,-0.052188228 -178,D33M,0.020699022,-0.060268599,0.001867865,-0.047416055,-0.057818308,-0.012184759,-0.005470992,0.046869035,-0.096813256,-0.12350587,0.002968672,-0.029353704,0.033089433,-0.040610545,-0.054221564,-0.026203678,-0.089432938,1.242270519,2.479057567,-2.597623955,-2.939754272,-2.282514938,-2.713197884,-2.600019897,-2.452632782,-3.387683124,-3.215082232 -179,D33L,0.017343449,-0.051276325,-0.015540177,-0.041125645,-0.123256094,-0.077431365,-0.027761312,0.062448209,-0.055784044,-0.093151724,-0.009400925,-0.028822359,-0.002257994,-0.021069002,-0.061182288,-0.112721032,-0.133791155,1.244755435,2.145553241,-1.289866704,-1.922747581,-0.674990669,-1.326394676,-1.465317116,-1.059883476,-1.697310498,-2.211875867 -180,D33N,-0.037355486,-0.118014366,-0.067515291,-0.072507328,-0.112246453,-0.061005645,-0.079784918,0.005073946,-0.039393628,-0.189686372,-0.046342359,-0.076516854,-0.058513727,-0.077954575,-0.067060081,-0.101106687,-0.123386219,1.529141047,2.441341006,-1.327163049,-1.201438576,-0.650238892,-2.294653351,-1.295632889,-1.19385154,-1.952631617,-1.012338527 -181,D33Q,0.007322337,0.055390603,0.074061349,-0.016990856,0.091680231,0.039116912,-0.024839626,0.039484299,-0.146520361,-0.086891374,0.19767258,0.063983096,0.084139601,0.021165611,-0.055147322,0.061061726,0.122298735,1.114191852,2.796448628,1.026545825,0.889540604,0.77407663,0.502977089,1.11729982,1.848834984,0.272078556,0.317271609 -182,D33P,-0.021065625,-0.802559472,-1.926844426,-2.416858057,-2.895012627,-0.015120976,-0.023574382,-0.018556868,-0.005551098,-0.584493614,-1.02062533,-2.013365571,-1.84032328,-2.422145831,-2.411570283,-2.397732773,-3.392292481,1.439836923,-0.109452601,-3.739536301,-2.787286354,-4.315875221,-4.836216408,-4.216392517,-2.541911003,-3.868911398,-2.029706323 -183,D33S,0.032601639,-0.037366995,-0.038649426,-0.038795675,-0.055098192,-0.009941255,-0.00042185,0.065625128,-0.068625717,-0.098808423,0.024074433,-0.08732652,0.010027669,-0.041447124,-0.036144225,-0.070404881,-0.039791503,1.346617838,2.392328891,-0.104741972,-0.345059525,0.861704742,-0.497300362,-0.548603531,0.005548813,-1.64705669,-0.287645316 -184,D33R,-0.015938911,-0.096471692,-0.02063636,-0.060886155,-0.055448761,0.000517267,-0.044070166,0.012192344,-0.050759813,-0.10515092,-0.087792464,-0.051898535,0.010625816,-0.036682286,-0.085090023,-0.005216029,-0.105681493,1.250163816,2.487257249,-0.070885849,-0.075153809,-0.383262787,-0.308354774,0.299405533,0.112936592,-0.132900268,0.284242443 -185,D33T,0.004202834,-0.038370529,-0.023354019,-0.055334612,0.00270366,-0.017381901,-0.034163901,0.042569568,-0.045460062,-0.086442097,0.00970104,-0.015408197,-0.03129984,-0.026593647,-0.084075576,0.00210796,0.00329936,1.266983826,2.593799908,-0.505052081,-0.942996872,0.141645103,-1.081496567,-0.835024345,0.192612274,-1.063348698,-0.665672228 -186,D33W,0.030054375,-0.095488369,-0.061563131,-0.06184637,-0.26217333,-0.089924785,-0.004443561,0.064552311,-0.204612899,-0.159113739,-0.031862999,-0.126771517,0.003645255,-0.084082485,-0.039610255,-0.272505082,-0.251841578,1.608665191,2.153229267,-5.381606976,-4.914779816,-5.428023735,-6.038625809,-5.518395729,-5.008209793,-5.618158526,-5.466240648 -187,D33V,-0.020273513,-0.084195864,-0.034279172,-0.073608704,-0.080936175,-0.024357951,-0.054246658,0.013699632,-0.050629135,-0.093137604,-0.075254123,-0.048094926,-0.020463417,-0.012392344,-0.134825063,-0.056970928,-0.104901422,1.354164364,2.434191365,-2.342069954,-2.645092911,-2.120745178,-2.367964386,-2.277355248,-2.299192047,-3.318185598,-2.571791168 -188,D33Y,-0.008606986,-0.085381589,-0.010297231,-0.058198773,-0.160994389,-0.072827319,-0.060259567,0.043045595,-0.063958889,-0.124501331,-0.046261846,-0.039034242,0.01843978,-0.029671108,-0.086726438,-0.159242808,-0.162745969,1.448498494,2.200759027,-4.627052341,-4.236046127,-5.501634796,-4.810698685,-4.362141617,-4.224740479,-4.626342701,-3.815463189 -189,A34C,-0.068932711,-0.034236007,-0.006441137,-0.034724992,-0.521398897,-0.016597971,-0.07661884,-0.061246581,-0.129251473,0.057239632,-0.125711646,-0.014511363,0.00162909,0.043383802,-0.112833785,-0.282587563,-0.760210231,0.822278583,1.613852689,-5.971443784,-5.804804459,-6.146641991,-6.23464447,-6.324600029,-5.346527969,-5.754721842,-2.762958867 -190,A34E,-0.003385583,0.033829253,-0.288512877,-1.774187303,-2.556684305,0.152784916,0.068072765,-0.07484393,-0.074891286,-0.026620708,0.094279214,-0.127160245,-0.449865508,-1.691999621,-1.856374984,-2.37894574,-2.73442287,0.975032155,0.707418231,-2.658605421,-1.346268784,-2.006614243,-4.087689255,-3.484255676,-2.36819915,-3.8940296,-0.61948546 -191,A34D,0.039054993,-0.060048405,-1.300400217,-2.243853935,-2.404831914,-0.0097123,0.070316675,0.00779331,0.033124746,-0.016749552,-0.103347257,-1.094721462,-1.506078972,-2.014748866,-2.472959003,-2.303754977,-2.50590885,2.680774685,1.269176658,-6.497422841,-5.734475174,-5.556617943,-7.568806015,-7.62168367,-6.005531403,-5.702284668,-2.703776642 -192,A34G,-0.027909528,-0.058421028,-0.020882787,0.003717636,-1.861298253,0.056961999,0.005028976,-0.060848031,-0.015885437,-0.03623098,-0.080611075,-0.037798817,-0.003966756,0.021835498,-0.014400226,-1.42788701,-2.294709495,0.698884994,1.32460961,-6.761407748,-6.723408401,-6.215696823,-7.54002906,-6.900638252,-6.427266205,-7.324677193,-5.597197711 -193,A34F,0.037697192,0.020944169,0.083382405,0.057913149,-0.922138302,-0.115116738,0.008864325,0.066530058,-0.032197439,0.009912086,0.031976251,-0.01195624,0.17872105,0.00595922,0.109867078,-0.659327839,-1.184948765,0.989580751,1.486046889,-5.778544209,-6.526846657,-6.281155838,-6.138587776,-6.269626038,-3.676504738,-4.099127336,-1.13754861 -194,A34I,-0.042221993,-0.062442994,-0.000783128,-0.010175306,-0.548549981,-0.004862668,-0.072984902,-0.011459083,0.029771617,-0.027015576,-0.097870411,-0.041245616,0.039679361,-0.007595263,-0.012755348,-0.401522997,-0.695576965,1.427464462,1.87887019,-2.182220406,-1.529569702,-2.229482826,-3.328270004,-2.019483032,-1.804296463,-2.051286022,1.647171791 -195,A34H,-0.003337041,-0.02819132,0.028280672,-1.492230192,-2.609230586,-0.0022504,0.013308898,-0.01998298,-0.176271186,-0.016610494,-0.039772146,0.005560821,0.051000522,-1.102792299,-1.881668085,-2.157715204,-3.060745967,2.206472218,1.462723899,-6.386438306,-7.68664991,-6.508765228,-5.771848877,-7.172161995,-4.792765518,-5.44767231,-2.54575115 -196,A34K,-0.077572353,-0.048104208,-0.067625124,-1.775609469,-2.635557452,0.057446671,-0.039264024,-0.115880682,0.09734742,-0.115887148,0.019678733,-0.065719386,-0.069530861,-1.441379129,-2.109839809,-2.730385239,-2.540729664,1.255795985,0.783212221,-6.063076888,-6.174085709,-5.438094688,-6.79254538,-6.598327621,-5.312331039,-5.556296837,-2.40478857 -197,A34M,-0.019095921,-0.032903227,0.06754402,0.033118193,0.003700525,0.09172502,-0.009891635,-0.028300206,0.059415267,-0.042361197,-0.023445256,0.025061093,0.110026946,-0.004921378,0.071157763,0.055454411,-0.048053362,1.115892828,2.801312931,-5.414141599,-5.639139267,-5.190563477,-5.497856606,-6.040427658,-4.702720985,-3.615274518,-1.389855643 -198,A34L,-0.023000883,-0.054643549,0.005779463,-0.002092054,-0.88252558,0.036740237,-0.042813322,-0.003188444,-0.040629136,-0.037388634,-0.071898463,-0.032637327,0.044196253,0.002141139,-0.006325246,-0.631842141,-1.133209018,1.045491769,1.513181738,-2.914341324,-3.222324448,-2.663490814,-2.665033012,-3.135467285,-2.88539106,-2.141117532,2.291497469 -199,A34N,0.022826294,0.006889193,-0.364289176,-1.6651285,-2.37743765,-0.041997954,0.034767024,0.010885564,-0.00279023,-0.02831812,0.042096505,-0.281772479,-0.446805872,-1.411013138,-1.919243861,-2.13367481,-2.621200489,2.394774782,1.485436099,-6.659808302,-6.87095829,-6.706091469,-7.148018738,-7.024010399,-5.549962616,-6.032115798,-3.638602074 -200,A34Q,0.008920508,0.044035444,0.029474761,0.048950552,-1.292157836,0.132280893,0.035596674,-0.017755659,-0.020197041,0.00293975,0.085131137,-0.005089305,0.064038826,0.018027905,0.079873198,-1.097371679,-1.486943992,0.618720061,1.33902711,-3.467140909,-2.784020546,-3.356804932,-4.099045433,-4.740491272,-2.355342361,-3.270409808,-1.592185337 -201,A34P,-0.01686929,-0.005024349,-0.746194557,-1.904493088,-2.678125708,0.001235385,-0.00337732,-0.03036126,-0.125354424,-0.02226301,0.012214313,-0.488370254,-1.004018859,-1.834834129,-1.974152047,-2.725900231,-2.630351184,1.707278438,0.801368581,-6.614716513,-7.02655616,-6.212445015,-6.988152252,-6.84356694,-6.002862198,-6.52291817,-4.304579203 -202,A34S,-0.002500661,0.00589873,0.016221825,0.031552192,-0.245824713,-0.0084807,-0.031467837,0.026466516,0.000378651,0.018720183,-0.006922724,-0.010723483,0.043167132,0.016764636,0.046339748,-0.221444517,-0.270204909,1.304766752,2.012985693,-2.022962837,-2.152516418,-2.186919075,-1.968950966,-2.114584366,-1.691843361,-2.728363201,-1.90000286 -203,A34R,-0.045602501,-0.034062096,-1.115838268,-1.872316469,-3.064020687,0.029656189,-0.030096758,-0.061108243,-0.147087824,0.002899104,-0.071023295,-0.868813697,-1.362862838,-1.838326464,-1.906306473,-2.632482553,-3.49555882,2.235596009,1.005925638,-5.318845952,-5.352927704,-5.192990135,-6.04935614,-6.13889711,-3.86005867,-4.02107564,-1.234196309 -204,A34T,-0.009567617,-0.023664035,-0.011399072,0.011472821,-0.410171144,0.000905863,-0.030373916,0.011238683,0.053473746,-0.032054077,-0.015273993,-0.02837167,0.005573526,0.010913688,0.012031954,-0.32196398,-0.498378308,1.301585591,1.883329033,-1.477271156,-1.695503471,-1.395476639,-1.507536469,-1.30777063,-1.480068573,-2.003452476,-0.997618545 -205,A34W,-0.026335074,-0.051258753,-0.071276705,-0.0173383,-1.029580625,0.069249331,-0.034185205,-0.018484942,0.053589173,-0.048933444,-0.053584062,-0.127959315,-0.014594094,-0.072415285,0.037738686,-0.836706307,-1.222454942,0.899560783,1.41538364,-4.343234914,-3.86549894,-6.750972023,-4.729335663,-4.449731445,-1.920636498,-3.467237446,-2.32485185 -206,A34V,0.033568335,-0.013579021,0.032664643,-0.000632127,-0.029961704,0.045825462,0.018366614,0.048770056,-0.052270978,-0.021534183,-0.005623859,-0.001960592,0.067289878,-0.012851373,0.011587119,-0.049626105,-0.010297302,1.128665717,2.294391512,-1.950976117,-1.27618129,-1.764005226,-2.328176918,-2.58455471,-1.80196244,-1.675558266,0.506115991 -207,A34Y,-0.014001053,0.024321005,-0.022033216,0.03149482,-1.621560847,-0.062116088,-0.024909325,-0.00309278,0.017561057,0.025619385,0.023022624,-0.040192781,-0.00387365,0.073748482,-0.010758842,-1.342080509,-1.901041185,0.514842202,1.317794607,-5.948204324,-7.88748056,-6.921452164,-5.970125244,-6.161019859,-2.800943794,-3.758984041,-0.410031 -208,E35A,-0.054752294,-0.014474191,0.036780184,0.054124349,-1.787649562,0.085854686,-0.004990799,-0.104513788,0.03151672,0.00956106,-0.038509441,0.017587937,0.055972431,0.064383369,0.043865328,-1.528966365,-2.046332759,0.422109774,1.307128758,-5.929663593,-5.421241562,-6.157147575,-6.011878281,-4.915717682,-7.142332863,-4.637283244,-1.338595644 -209,E35C,-0.077656886,-0.005266344,-0.004750114,-1.25494591,-2.420916886,0.006849353,-0.051633728,-0.103680043,0.153330431,0.053455518,-0.063988205,0.009833696,-0.019333924,-0.763250954,-1.746640865,-2.494350531,-2.347483241,0.686898425,0.775656415,-10.56504296,-10.31532274,-9.78569796,-11.55889533,-10.06498613,-11.10031265,-6.725186445,-4.162726006 -210,E35D,-0.049983983,-0.05543922,0.055266173,-0.866293229,-2.119519212,0.035918553,-0.011261817,-0.088706148,0.007471577,0.017922579,-0.128801019,0.03070266,0.079829685,-0.445782951,-1.286803506,-2.000195937,-2.238842487,1.573737617,1.358800403,-6.456120277,-5.989195358,-6.651833023,-5.221567116,-6.513598358,-7.904407532,-5.858720938,-3.095308477 -211,E35G,-0.090209224,-0.073698232,0.000316768,-0.785331535,-2.321290613,-0.01236886,-0.043300959,-0.137117488,-0.007883155,0.006389911,-0.153786374,-0.00000455,0.000638086,-0.409933749,-1.16072932,-2.018537393,-2.624043832,1.543068385,1.359011752,-9.159798048,-9.170754501,-8.324930481,-9.442117142,-7.633027466,-11.22816065,-6.877165706,-3.619510497 -212,E35F,-0.114791574,-0.096938715,-1.271659033,-2.53993936,-2.851699887,-0.003379612,-0.105216903,-0.124366245,-0.050112361,0.052402794,-0.246280223,-1.090035746,-1.453282319,-2.661050294,-2.418828426,-2.528827011,-3.174572762,0.475731045,0.083517909,-11.44289333,-9.704123276,-10.50048055,-14.35192181,-10.80749157,-11.85044943,-6.411293227,-2.200181798 -213,E35I,-0.080646986,-0.005495513,0.037291055,-1.571022667,-2.987540701,0.021542896,-0.055351893,-0.105942078,-0.075997467,0.038356534,-0.049347559,0.027349853,0.047232256,-1.107936126,-2.034109208,-2.929955352,-3.045126049,0.727102253,0.740357232,-9.349729607,-8.783774445,-8.669628281,-10.99530862,-10.3713215,-7.928615181,-5.341833806,-1.557977324 -214,E35H,-0.067183403,0.000484976,-0.45862226,-1.697291208,-2.772221373,0.038553727,-0.037947849,-0.096418957,0.004969192,0.05469459,-0.053724639,-0.31156148,-0.60568304,-1.661050294,-1.733532122,-2.55001631,-2.994426436,1.411899901,0.775323933,-12.23343287,-11.49127119,-11.79974329,-12.67571156,-12.44503737,-12.75540096,-9.901583493,-8.1113978 -215,E35K,-0.081154805,-0.035719009,-0.132693364,-1.698474752,-2.940703589,-0.019899121,-0.034532148,-0.127777462,-0.070547341,-0.015754243,-0.055683775,-0.112701468,-0.15268526,-1.485478216,-1.911471288,-2.871768873,-3.009638305,0.763399323,0.710039475,-7.610294916,-7.12388768,-6.81177607,-9.511837067,-7.733923103,-6.870050659,-6.747037864,-5.06620328 -216,E35M,-0.039232433,-0.025135941,0.045301033,-0.466766462,-1.946449764,0.000911017,-0.006715365,-0.0717495,0.00110931,0.0630067,-0.113278582,0.040223086,0.050378979,-0.210724668,-0.722808256,-1.979778032,-1.913121496,1.298937011,1.33185026,-10.6843925,-10.1668725,-10.4805885,-13.3241358,-11.29235183,-8.158013863,-7.271198486,-3.67180166 -217,E35L,-0.104493531,-0.053989756,-1.025849724,-2.061794733,-2.885752479,-0.020752785,-0.082659046,-0.126328015,-0.040064223,0.014028477,-0.122007988,-0.608822464,-1.442876983,-2.047072938,-2.076516528,-2.583856436,-3.187648522,1.693837753,0.732852615,-8.891727443,-7.988080879,-9.048277542,-11.11329454,-9.207010277,-7.101973976,-5.506019503,-1.521149934 -218,E35N,-0.022779565,0.01323896,0.033090159,-1.343693211,-2.741755203,-0.001021363,0.033303183,-0.078862312,-0.030973756,0.009403081,0.017074838,-0.008710247,0.074890565,-1.208911328,-1.478475094,-2.456899286,-3.026611119,0.755756999,0.733534126,-10.12875914,-9.110432457,-9.88542495,-10.73626605,-10.65611533,-10.25555692,-8.2885312,-5.589610701 -219,E35Q,-0.091175329,-0.048267773,-0.015757543,0.005687481,-0.608613565,0.087170424,-0.092478571,-0.089872087,0.017786863,0.02622783,-0.122763375,-0.024490834,-0.007024251,0.029303091,-0.017928129,-0.462320981,-0.754906148,0.832654265,1.49692326,-5.628269211,-4.975271912,-5.197906532,-6.239145912,-5.31126384,-6.417757858,-5.257639036,-3.958922662 -220,E35P,-0.0464076,-0.874068752,-1.980774861,-2.26866403,-3.388924727,0.031209829,-0.026228315,-0.066586885,0.046561018,-0.606005945,-1.142131558,-1.928686029,-2.032863692,-2.216399349,-2.320928711,-3.038418575,-3.739430878,1.563351876,-0.022110665,-11.60054997,-11.08789054,-11.04034538,-11.88155006,-11.2649954,-12.7279685,-8.270195519,-6.187353593 -221,E35S,-0.041127627,0.000752487,0.042683544,-0.36569859,-2.463913496,0.030181533,-0.017427634,-0.06482762,-0.046628539,0.041250961,-0.039745988,0.002342739,0.083024349,-0.224426421,-0.506970758,-2.158156118,-2.769670873,1.191564991,1.301815089,-8.41293336,-8.008426086,-7.693069252,-9.345964584,-8.173151131,-8.844055748,-6.341116953,-3.424305725 -222,E35R,-0.104567601,-0.041260662,0.002856633,-1.515880974,-3.10440097,0.023840781,-0.059047925,-0.150087276,0.015605385,-0.027614039,-0.054907284,0.033069712,-0.027356447,-1.198855775,-1.832906172,-2.929955352,-3.278846588,0.562969525,0.717426881,-8.530944913,-8.687296028,-7.94095298,-8.636654762,-8.079344864,-9.310475929,-6.614908139,-4.829754618 -223,E35T,-0.076813588,-0.026697341,-0.053754188,-1.514602217,-2.887142666,0.007396327,-0.044531151,-0.109096024,0.014853811,0.003803928,-0.05719861,-0.050295223,-0.057213152,-1.267427468,-1.761776966,-2.265537954,-3.508747378,0.873050732,0.746189438,-8.29855799,-7.909556831,-7.356843201,-8.866647652,-8.376646805,-8.983095459,-6.524019923,-2.583972736 -224,E35W,-0.050557561,-0.324607287,-1.751070295,-2.300249029,-3.040675803,-0.008750992,-0.038171669,-0.062943453,0.015368329,-0.119428861,-0.529785713,-1.433940156,-2.068200434,-2.043872771,-2.556625286,-2.990830734,-3.090520872,0.970529305,0.078243178,-12.10494565,-11.17605563,-11.96057906,-13.83641078,-10.21706438,-13.33461838,-7.24578967,-3.941630306 -225,E35V,-0.112075476,-0.039967375,0.015119378,-1.007319116,-2.288299032,0.063008372,-0.063553663,-0.160597288,0.029912867,0.019433127,-0.099367876,0.047364873,-0.017126117,-0.530785369,-1.483852863,-2.041433766,-2.535164298,1.741530145,1.391816015,-8.895206174,-8.547556992,-8.08642028,-9.265197525,-9.850103485,-8.726752586,-6.490059198,-2.03094472 -226,E35Y,-0.059610389,-0.05128201,-1.475213054,-2.348920065,-3.049756216,-0.038634016,-0.020131741,-0.099089036,-0.083197172,-0.011766275,-0.090797745,-1.199219286,-1.751206822,-1.9810872,-2.716752929,-3.024955176,-3.074557256,2.389725386,0.973344574,-13.57886199,-11.93632243,-12.60367753,-16.40659492,-13.04974473,-13.89797034,-9.350226271,-7.092387599 -227,D36A,-0.041654702,-0.083681227,0.017367946,-0.009070765,-0.005953824,-0.020641471,-0.045974975,-0.037334428,0.001909752,-0.050726318,-0.116636136,0.110959213,-0.076223322,0.022966929,-0.041108458,0.021411218,-0.033318865,1.258591366,2.702723941,1.17832645,2.025713486,0.669059891,1.932755959,1.24298114,0.021121773,-2.390065486,1.134171994 -228,D36C,0.037691899,-0.065358203,0.023380895,0.041438003,-0.099956783,0.02984313,0.041440634,0.033943163,0.158117293,-0.031714413,-0.099001992,0.115019671,-0.068257882,0.067819744,0.015056261,-0.064680243,-0.135233323,1.265505634,2.504147753,-4.122123158,-3.54815966,-4.228758247,-4.134473396,-3.938155594,-4.761068893,-6.441918187,-4.687457341 -229,D36E,0.00149874,-0.055658765,0.008684261,0.03100566,0.001811128,-0.057683422,-0.005926275,0.008923755,-0.045128223,-0.00697742,-0.104340109,0.063509852,-0.04614133,0.080507214,-0.018495894,0.062692427,-0.059070172,1.543610422,3.106887046,0.513113217,0.694987953,0.327084457,0.778792824,0.721942314,0.042758537,-1.899136343,0.313285189 -230,D36G,-0.038281083,-0.037177628,0.007476476,0.018158538,0.035435688,0.085444166,-0.056294704,-0.020267461,-0.031177672,0.005444279,-0.079799535,0.084869454,-0.069916502,0.054560987,-0.018243911,0.055260803,0.015610573,1.19868808,2.897576494,-0.896907077,0.134695778,-1.354722221,-0.39862751,-0.495389908,-2.370491524,-2.70406201,-0.909365967 -231,D36F,0.006982974,-0.057743486,0.021463197,0.005932447,-0.068770939,-0.063994162,0.012960631,0.001005316,-0.086253935,-0.050499308,-0.064987663,0.12085578,-0.077929387,0.046410705,-0.034545811,-0.036829397,-0.100712481,1.237023233,2.517427644,-4.334679076,-3.689788223,-4.303773758,-5.053691238,-3.774185165,-4.851956993,-6.159038138,-4.651269194 -232,D36I,-0.028773653,-0.107851677,-0.041614333,-0.027543459,-0.069870489,-0.040287771,0.004518164,-0.062065469,0.071261357,-0.059895601,-0.155807753,0.00957589,-0.092804556,-0.009285608,-0.045801309,-0.062330925,-0.077410053,1.261343793,2.338969055,-2.418640654,-1.631323639,-2.629121178,-2.597061943,-1.869193184,-3.366503326,-5.043325606,-2.83251096 -233,D36H,0.007738779,-0.079741578,-0.003141004,0.009838892,-0.026165024,0.002515126,0.019838794,-0.004361237,-0.033572571,-0.08314075,-0.076342406,-0.010712439,0.004430431,-0.016090397,0.03576818,-0.004288423,-0.048041624,1.203635836,2.578888789,-0.996185928,-0.548338234,-0.64699234,-1.089374222,-0.73636763,-1.959857216,-2.729143392,-1.496478581 -234,D36K,0.007690486,-0.053171709,0.051823025,0.050021068,-0.004920756,0.015759236,-0.016535098,0.03191607,0.111138871,0.030581339,-0.136924756,0.117716862,-0.014070812,0.122077103,-0.022034968,0.066865724,-0.076707235,1.078988956,2.882541829,1.325151903,1.751151283,0.975171875,1.549388695,1.664243568,0.685804092,-2.034953443,0.681316508 -235,D36M,0.021369936,-0.059121185,0.049166729,0.06535707,0.060808625,0.048310253,0.013548257,0.029191614,0.003335833,-0.016516555,-0.101725814,0.109577537,-0.01124408,0.067225966,0.063488174,0.094424803,0.027192446,1.132529104,2.959490069,-3.523521303,-3.086010918,-3.51147319,-3.344761864,-2.990655678,-4.684704865,-5.692881476,-3.786905558 -236,D36L,-0.033029528,-0.079211604,-0.005545978,-0.011029001,-0.015402454,0.019561399,-0.034586281,-0.031472774,-0.032523208,-0.000963614,-0.157459593,0.042316187,-0.053408142,0.035547197,-0.057605199,0.006038258,-0.036843165,1.074439185,2.578544252,-1.798847711,-1.282580879,-1.939139725,-1.752561584,-1.48772892,-2.532227448,-3.692724798,-2.23926373 -237,D36N,-0.041940973,-0.036382781,-0.003001778,0.043017768,0.044241268,-0.030818643,-0.030130111,-0.053751835,0.029920976,0.008510589,-0.081276151,0.055680446,-0.061684002,0.091220654,-0.005185119,0.098314052,-0.009831517,1.053550075,2.961504453,0.015303883,0.191889465,-0.104647171,-0.372904961,0.452985214,-0.090803131,-3.164600886,-0.680816572 -238,D36Q,-0.074271277,-0.165097932,-0.024394392,0.008824993,-0.016961135,-0.019975333,-0.102360732,-0.046181821,-0.054743992,-0.105559122,-0.224636742,0.072972902,-0.121761686,0.045708553,-0.028058567,0.030947854,-0.064870123,1.145365088,2.750096131,0.679118826,1.201101547,0.570516068,0.961756157,0.935736923,-0.273516563,-2.095782063,0.240447817 -239,D36P,-0.058013956,-0.081964043,-0.018619588,-0.293351642,-2.091987757,-0.047257492,-0.057047676,-0.058980236,-0.065450029,-0.051290961,-0.112637125,0.045483555,-0.08272273,-0.173586388,-0.413116896,-1.844374098,-2.339601416,1.113016357,1.328069427,-3.122200893,-2.461625061,-3.296723984,-3.074876526,-2.626273758,-4.151505135,-5.37002159,-3.290637286 -240,D36S,0.002656817,-0.053904553,0.021143805,0.0112443,0.009267077,-0.037758927,0.005249834,0.0000638,-0.062645815,-0.002135822,-0.105673284,0.055568955,-0.013281345,0.045317406,-0.022828807,0.019158097,-0.000623944,0.971461507,2.500686899,1.146971872,1.786855782,0.777179535,1.135468925,1.35343132,0.681923798,-1.175794936,0.235481394 -241,D36R,-0.020563764,-0.042728804,0.029087107,0.029128778,0.049957801,0.007559521,-0.037904493,-0.003223034,-0.038377069,-0.012065483,-0.073392124,0.067943719,-0.009769505,0.05623505,0.002022506,0.041990319,0.057925282,1.136774912,2.734130997,0.483836552,0.550234627,1.162935135,0.997429718,0.340035393,-0.63145211,-2.323415622,0.919638615 -242,D36T,-0.016305262,-0.061606735,0.008844727,0.003222114,0.006112565,-0.045103232,-0.010731224,-0.021879299,0.009255274,-0.008797199,-0.114416271,0.110882282,-0.093192828,0.045342593,-0.038898366,0.030647421,-0.018422291,1.096146598,2.673427032,0.259143584,0.525711655,0.122106758,1.131858086,0.072347626,-0.556306206,-1.939319155,-0.429911827 -243,D36W,0.025875073,-0.039805279,0.011496519,0.029774255,0.071250188,0.046530532,0.047029115,0.00472103,-0.053315644,-0.029152196,-0.050458362,0.041174085,-0.018181047,0.003281248,0.056267262,0.073345242,0.069155133,1.248661168,2.965849074,-4.647956546,-4.106363586,-4.422695961,-4.963425613,-4.264058922,-5.483238647,-7.031733203,-5.35243121 -244,D36V,-0.012786281,-0.059101552,0.048026803,0.023246056,0.000466563,0.02584015,0.019853914,-0.045426475,-0.053874383,-0.017130443,-0.10107266,0.098818223,-0.002764617,0.022729257,0.023762855,0.042571588,-0.041638463,1.027110332,2.696673147,-1.855441956,-1.300460403,-1.916375,-1.594932251,-1.426581413,-3.03886071,-3.732458621,-2.205054778 -245,D36Y,-0.049795134,-0.107311591,-0.050978622,-0.01491836,-0.165573091,-0.033762523,-0.086623169,-0.012967099,0.071283062,-0.064808225,-0.149814957,0.001932698,-0.103889942,0.020719817,-0.050556536,-0.120447945,-0.210698236,1.362441836,2.26562992,-3.043504417,-2.388603302,-3.086906067,-3.959058472,-2.226702484,-3.556251762,-5.588143401,-2.987695834 -246,Q37A,0.013475575,-0.034838865,-0.026500828,-0.010441513,0.008497057,-0.020677197,-0.001737119,0.028688268,0.053909946,-0.046398117,-0.023279612,-0.105808289,0.052806634,-0.085353139,0.064470114,0.002860034,0.014134079,1.187417751,2.478665957,-2.198182945,-0.82109597,-3.896114616,-1.98023291,-3.415622971,-0.877848259,-5.030943532,0.233595649 -247,Q37C,0.002095961,-0.037353162,0.054402687,-0.003444391,-0.092868754,0.03202472,0.018661609,-0.014469687,0.136528183,-0.117044683,0.04233836,-0.005949656,0.11475503,-0.079104555,0.072215773,-0.0365207,-0.149216808,1.35029261,2.442460732,-6.265946878,-5.166815033,-7.35081115,-6.81415303,-6.505281998,-5.49267318,-7.652492333,-3.852542789 -248,Q37E,-0.01183281,-0.029650997,0.012494158,0.044003893,0.004526454,0.096054512,-0.046759292,0.023093673,-0.037504503,-0.017236691,-0.042065302,-0.054194488,0.079182804,-0.030055734,0.11806352,0.013645661,-0.004592754,1.12192323,2.597957697,-1.426059584,-0.395681175,-2.521451088,-2.095011787,-1.599935547,-0.518218323,-3.377207111,0.443794891 -249,Q37D,-0.003060218,-0.022749737,0.037064723,-0.002470336,-0.085462237,0.006734072,-0.012668745,0.00654831,0.056028816,-0.019680931,-0.025818543,-0.043595075,0.11772452,-0.09285454,0.087913868,-0.054366981,-0.116557493,1.360552195,2.329526199,-2.653641107,-1.766590149,-2.321700912,-3.832107391,-3.656997963,-1.69080912,-4.439020311,0.102785754 -250,Q37G,-0.009567354,-0.011964871,-0.006138523,-0.016341362,-0.013549446,0.030613001,-0.009323832,-0.009810875,0.057211557,-0.033157149,0.009227407,-0.057139692,0.044862647,-0.063992496,0.031309773,-0.018251812,-0.008847079,1.272649724,2.456592866,-3.938447034,-2.809903435,-4.36294371,-4.994198204,-4.66131871,-2.863871109,-5.416925494,0.105815729 -251,Q37F,-0.03867964,0.014379738,-0.018430252,0.008288437,-0.012968656,0.04203137,-0.017779355,-0.059579924,0.070406086,0.029200746,-0.000441271,-0.065329566,0.028469063,-0.025370819,0.041947692,0.022214785,-0.048152096,1.15107975,2.558686959,-6.42908054,-6.090999146,-6.27020372,-7.059609718,-6.317036606,-6.407553513,-7.886565614,-4.25324109 -252,Q37I,0.015214917,-0.012544638,0.026633674,0.004254193,0.009937148,0.022014634,0.013224136,0.017205698,0.029250407,0.03375314,-0.058842415,-0.012489985,0.065757333,-0.009861515,0.0183699,0.024511292,-0.004636997,1.246358117,2.740319173,-5.107932501,-4.538673508,-5.350080292,-5.281901314,-5.302417053,-5.06659034,-6.673518357,-3.568718588 -253,Q37H,-0.018251094,-0.059180152,0.009643872,0.006968992,0.00280529,-0.044123375,-0.009581504,-0.026920683,0.028903565,-0.023204638,-0.095155666,-0.017266136,0.03655388,0.005619248,0.008318736,-0.011248353,0.016858932,1.107887337,2.59724708,-3.294033688,-2.674552109,-3.550200294,-3.628579964,-3.53234388,-3.084492195,-5.044124948,-2.184843352 -254,Q37K,0.015703717,-0.050748527,0.031059995,0.018645675,0.011905738,0.049587569,0.00772575,0.023681683,0.091976244,-0.049679929,-0.051817124,-0.044590215,0.106710204,-0.029438871,0.066730221,-0.029438871,0.053250347,1.21871546,2.42415044,-1.264592827,-0.490385307,-2.390751076,-1.225363953,-1.352695297,-0.863768501,-2.77053081,0.001415429 -255,Q37M,0.022171242,-0.040002664,0.022624394,0.032960689,0.027739205,0.012116824,0.002994121,0.041348362,0.023764574,-0.035455197,-0.04455013,-0.039614308,0.084863095,-0.034310764,0.100232142,0.042483059,0.01299535,1.075444182,2.612986375,-5.149427977,-4.986198494,-5.539893768,-5.425359909,-5.337031158,-4.458656555,-7.091183707,-3.542858139 -256,Q37L,0.012956829,0.015188303,0.023039825,0.034235913,0.01388525,-0.019787242,0.020760738,0.005152919,0.025682656,0.018656742,0.011719863,-0.009331208,0.055410858,-0.010290697,0.078762523,0.023704531,0.004065969,1.128423399,2.636717892,-3.516231752,-4.02344722,-3.329242516,-3.333450897,-3.37800827,-3.517009857,-4.87426925,-2.083886688 -257,Q37N,-0.007810898,-0.017334184,0.011595097,0.003896463,0.020191115,0.018040362,-0.00288427,-0.012737526,0.005168492,-0.035902736,0.001234369,-0.056722238,0.079912432,-0.097639976,0.105432901,-0.026521028,0.066903257,1.362411502,2.520843974,-2.824168452,-2.2954245,-2.474125084,-3.895144081,-2.653942413,-2.802206184,-5.143270766,-0.604549101 -258,Q37P,0.022477996,-0.01054113,0.012721455,-1.309196589,-2.202043505,-0.047024175,0.045456844,-0.000500852,-0.017297097,-0.007797084,-0.013285175,-0.027729774,0.053172684,-0.923451937,-1.69494124,-2.050917613,-2.353169396,2.139204527,1.503376333,-5.541554872,-4.015758614,-6.828863564,-5.875159439,-6.272567169,-4.715425575,-6.365100421,-1.889933002 -259,Q37S,0.011986919,-0.007524843,0.002529432,0.023025887,0.007432733,-0.007627401,0.017127231,0.006846607,0.073721199,-0.017090793,0.002041107,-0.042124164,0.047183027,-0.022278521,0.068330294,0.014285209,0.000580257,1.203230196,2.740091345,-2.185639679,-0.899332283,-3.673700256,-2.132792892,-2.413339714,-1.809033249,-5.210528294,0.008645027 -260,Q37R,-0.021317681,-0.004005672,0.007115336,0.015062096,0.03108761,0.022157542,-0.021656908,-0.020978453,0.040234549,-0.005110079,-0.002901264,-0.046307854,0.060538526,-0.014770083,0.044894275,0.027082115,0.035093104,1.33432194,2.864895717,-0.699679449,0.387381828,-1.437676643,-1.080140366,-1.478202469,0.110240402,-2.191038873,0.629104805 -261,Q37T,0.020963225,-0.0351101,0.008072792,0.010537418,-0.011476302,-0.011794972,0.031487933,0.010438517,0.083069955,-0.054105434,-0.016114765,-0.071051344,0.087196927,-0.067702372,0.088777207,-0.004622112,-0.018330491,1.341116036,2.627532819,-2.229295645,-0.862056168,-4.218545349,-1.791866051,-2.702212692,-1.571797966,-3.820195376,-0.607356605 -262,Q37W,-0.007209319,0.004655879,-0.00449747,0.017618204,-0.029962936,-0.019107805,-0.023537027,0.00911839,0.023515644,-0.013465428,0.022777186,-0.040018372,0.031023432,-0.031029987,0.066266395,-0.004012933,-0.055912939,1.298987461,2.651238149,-5.941871494,-5.351138023,-6.511625778,-6.232775169,-6.121073639,-5.492744858,-7.24363798,-4.244214405 -263,Q37V,0.005571385,-0.014868846,-0.008102534,-0.008003736,-0.009010772,-0.001559684,-0.02375958,0.03490235,0.030535424,-0.051932205,0.022194513,-0.057983344,0.041778276,-0.076168127,0.060160655,-0.010336604,-0.00768494,1.276755325,2.520657352,-4.566301718,-4.351111183,-4.948481682,-4.371912758,-5.398552505,-3.761450462,-6.117442707,-2.677320645 -264,Q37Y,0.032321182,-0.013275174,0.009741443,0.016868122,-0.050090694,-0.010390251,0.015933753,0.04870861,0.06277607,-0.046523644,0.019973296,-0.113911245,0.133394131,-0.076492015,0.110228259,-0.025178816,-0.075002571,1.437161742,2.522602388,-5.651566237,-4.83251799,-5.976137802,-6.497289169,-5.637135857,-5.314750366,-7.424068471,-3.309527611 -265,L38A,-0.036084275,-0.024499052,-0.025508815,-0.032336151,-1.581118647,0.097808454,-0.016201131,-0.055967418,-0.069158477,0.014315446,-0.06331355,-0.008105304,-0.042912325,-0.005063157,-0.059609144,-1.264756797,-1.897480496,0.760242283,1.339958771,-8.685752034,-7.431558624,-8.695046364,-7.080600166,-10.66182262,-9.559732391,-3.94502692,0.371953503 -266,L38C,0.032500706,0.054308276,0.036401874,-0.051520496,-2.132422185,0.07841328,0.073338782,-0.008337371,0.030227026,0.067964805,0.040651747,0.00962721,0.063176538,-0.05262911,-0.050411882,-1.942891162,-2.321953207,0.820580853,1.303259792,-10.53306749,-10.61580608,-9.699528091,-11.2616125,-12.13649152,-8.951899254,-6.358900087,-2.277954587 -267,L38E,0.007020666,0.053261009,0.015303334,0.027263698,-1.69693259,0.080244211,0.026734183,-0.012692852,-0.105300618,0.048052061,0.058469956,-0.034849075,0.065455742,0.031571889,0.022955507,-1.494596234,-1.899268945,0.744442581,1.324672427,-11.38094572,-11.95427306,-10.10961348,-12.08169437,-12.03071597,-10.72843171,-6.443532824,-2.41408747 -268,L38D,-0.018575298,0.030273038,0.026986524,0.075720819,-1.72549043,0.051976555,-0.04156863,0.004418035,-0.148596904,-0.039460178,0.100006253,-0.024509668,0.078482716,0.078367198,0.07307444,-1.573675305,-1.877305555,0.62541432,1.313824582,-11.45223208,-12.36083303,-10.19883658,-12.47675761,-11.56261189,-10.66212132,-5.705134796,-2.502319647 -269,L38G,0.000641591,0.016289419,-0.022557695,-0.019264259,-1.413216117,0.088820831,0.038925307,-0.037642125,-0.041049764,0.036695868,-0.004117031,0.002617341,-0.04773273,-0.029052161,-0.009476357,-1.007953808,-1.818478426,0.826863204,1.373383151,-11.38058441,-10.71061833,-10.76401826,-11.52271614,-12.20099622,-11.70457311,-5.774860003,-2.00599906 -270,L38F,0.009911524,-0.01435726,0.039812405,-0.041355939,-0.674853968,0.093093476,-0.00657086,0.026393907,-0.18542828,-0.020990791,-0.007723729,0.000779813,0.078844996,-0.073624862,-0.009087016,-0.436949398,-0.912758538,1.200856462,1.682244233,-6.442623038,-9.133624146,-4.64315345,-6.614286224,-5.674581047,-6.147470322,-4.481184371,0.398168927 -271,L38I,0.021416114,-0.032329569,-0.031169739,-0.049498635,-0.372458419,-0.010307277,0.023948795,0.018883432,-0.207756202,-0.055727949,-0.008931189,-0.050159115,-0.012180363,-0.069728123,-0.029269146,-0.295545694,-0.449371144,1.471211463,2.005215671,-3.483750658,-3.818187271,-3.283207764,-3.981381401,-3.556882553,-2.779094299,-3.80013138,-1.237287984 -272,L38H,0.027157683,0.007122961,-0.00741479,-0.034864848,-1.263921658,0.070474713,0.034447543,0.019867822,-0.111994319,0.008734497,0.005511425,-0.031509125,0.016679546,-0.06598458,-0.003745116,-1.049702618,-1.478140697,0.978687832,1.395729137,-10.21470181,-11.35886645,-8.569752869,-11.82796991,-10.57031552,-8.746604286,-4.116264684,-0.169269112 -273,L38K,-0.077827682,0.035299117,0.003382869,-0.067947336,-2.224309184,0.134057691,-0.02282425,-0.132831113,-0.20708471,0.048881282,0.021716951,-0.006466384,0.013232121,-0.023621074,-0.112273598,-1.823281259,-2.625337108,0.58159807,1.301765008,-10.89395408,-13.39562808,-8.650029572,-11.49820211,-10.24843256,-10.6774781,-5.561402256,-0.434391011 -274,L38M,0.006844302,-0.013503707,-0.039752019,-0.018308208,0.039525158,0.110577646,0.027613086,-0.013924482,-0.125715083,-0.035207978,0.008200564,-0.04085002,-0.038654018,-0.035917984,-0.000698432,-0.040556189,0.119606504,1.450314855,2.561284008,-7.186625591,-7.741253426,-6.658322807,-7.053589256,-7.343015472,-7.136946991,-6.4878378,-2.784617623 -275,L38N,-0.021271976,0.082115635,-0.035783916,0.016296568,-1.721639345,0.043558539,-0.005108255,-0.037435697,-0.115417752,0.046178734,0.118052535,-0.056739645,-0.014828186,0.011706006,0.02088713,-1.446386409,-1.996892281,0.739385411,1.326643906,-10.91688667,-12.83726284,-8.678019066,-12.49053517,-12.18524563,-8.393370628,-5.327972442,-1.71684058 -276,L38Q,-0.042838183,0.005543534,-0.015836337,0.028416585,-1.495932181,0.084381077,-0.049628574,-0.036047792,-0.033398221,0.03924487,-0.028157803,-0.030102768,-0.001569906,0.000670087,0.056163082,-1.598395473,-1.393468888,0.615607525,1.311533522,-9.822292548,-10.91223233,-8.581262558,-11.12782203,-9.336752007,-9.153393814,-6.016036565,-1.631162104 -277,L38P,-0.022086388,-0.020702261,-0.037503621,-0.046259049,-1.51455909,0.045366008,-0.009084821,-0.035087954,-0.111735146,-0.011554845,-0.029849676,-0.049179342,-0.025827899,-0.051786025,-0.040732073,-1.418352252,-1.610765927,0.707074608,1.327017295,-12.70543403,-14.05712273,-11.88686693,-12.43411126,-13.13324912,-12.01582009,-7.162804476,-2.621731508 -278,L38S,-0.025628826,0.005934258,-0.015047861,-0.047805993,-0.884596349,0.091171065,-0.016748463,-0.034509188,-0.064305145,0.037833044,-0.025964528,-0.012456077,-0.017639645,-0.051836854,-0.043775131,-0.656627583,-1.112565114,1.111638181,1.535099406,-7.654905255,-7.71889605,-6.487159119,-8.63528656,-9.574180824,-5.859003723,-3.237204007,0.051233415 -279,L38R,-0.008876925,0.002090757,-0.021993545,-0.217223563,-2.052487335,0.053667173,0.015666904,-0.033420754,-0.104741429,0.028816124,-0.02463461,-0.057494235,0.013507145,-0.175419483,-0.259027643,-1.921249237,-2.183725432,1.326826835,1.32411559,-10.3081636,-11.06804789,-9.447527878,-10.83105425,-10.43445696,-9.75973101,-4.772213727,-1.708874527 -280,L38T,-0.006831895,0.036676415,-0.01770499,-0.027612948,-0.369701482,0.116769218,0.001163389,-0.014827178,-0.133721363,0.005189216,0.068163614,-0.042459897,0.007049918,-0.037734465,-0.01749143,-0.346160004,-0.393242959,1.207653389,1.767181328,-7.403314153,-7.900249413,-7.485204109,-7.089641296,-10.19161333,-4.349862617,-4.490535058,-0.680221755 -281,L38W,0.007240236,0.008649317,0.01615162,-0.061031971,-0.62371773,0.163826682,0.015014261,-0.000533789,-0.093686772,-0.008158053,0.025456687,-0.013508344,0.045811584,-0.105235619,-0.016828323,-0.460997393,-0.786438067,1.660141949,1.997512823,-12.24511037,-13.64904004,-10.95416203,-13.3831639,-11.896615,-11.34257085,-7.489689975,-4.691202126 -282,L38V,-0.078594625,-0.025269513,-0.050148182,-0.024244138,-1.660237684,0.081376983,-0.053496516,-0.103692733,-0.108244041,-0.005891084,-0.044647941,-0.040916537,-0.059379826,-0.006722659,-0.041765616,-1.313408125,-2.007067243,0.81897376,1.340261743,-4.433360303,-3.689975327,-3.934018967,-4.921222176,-5.044612007,-4.576973038,-3.409149002,-0.885409642 -283,L38Y,-0.020096759,0.006630871,0.026163047,0.008026452,-0.342970173,0.138370292,-0.031373708,-0.00881981,-0.133750813,0.026584873,-0.013323132,0.050596334,0.00172976,-0.020492756,0.036545659,-0.237935651,-0.448004694,1.508878967,2.143939584,-10.25337876,-13.24119003,-7.650171768,-11.66278089,-9.965408974,-8.747342125,-3.964063777,0.095320722 -284,G39A,-0.018175581,-0.017296823,0.004159079,-0.016124848,-0.051723869,0.006438169,-0.010421729,-0.025929432,0.016051569,-0.053339386,0.01874574,-0.002044464,0.010362621,-0.017374096,-0.014875599,-0.075227393,-0.028220345,1.26573419,2.330842986,-2.305557086,-2.183359558,-2.411863701,-1.314909004,-2.628063873,-2.989589294,-2.287964036,-2.369941989 -285,G39C,-0.1071468,-0.125044225,-0.08729745,-0.020649595,-1.109586321,0.005034329,-0.098605507,-0.115688092,0.066509415,-0.056326918,-0.193761531,0.003578724,-0.178173623,-0.006897919,-0.034401271,-0.65553961,-1.563633032,0.952337906,1.476119502,-5.220351968,-4.784487816,-5.658764175,-4.626481644,-5.418281311,-5.613744896,-5.235818819,-5.899151552 -286,G39E,-0.025114555,-0.032570732,0.001576919,0.020539605,-0.046368472,-0.003987683,-0.007564349,-0.042664761,-0.012997076,-0.029316733,-0.035824731,0.012801753,-0.009647915,0.011229612,0.029849598,-0.013169385,-0.079567559,1.238612166,2.494572306,-2.20269892,-1.951557137,-2.872245552,-1.645568146,-1.419238785,-3.124884979,-3.027045757,-2.233849494 -287,G39D,-0.059309297,-0.038062946,0.005496867,-0.004272313,-0.041516899,-0.027531486,-0.023204581,-0.095414012,0.018124438,-0.005584921,-0.070540971,0.02451263,-0.013518896,0.025626481,-0.034171106,-0.002435793,-0.080598004,1.267745653,2.641942283,-0.905509631,-0.975800125,-0.892875961,-0.479511932,-0.3902351,-1.789125038,-1.172135141,-0.805415896 -288,G39F,-0.086846373,-0.094038668,-0.016561159,0.042664764,-0.618090784,0.071205494,-0.055588349,-0.118104396,-0.003064861,0.000366854,-0.188444189,-0.00603342,-0.027088898,0.074718945,0.010610583,-0.426546364,-0.809635204,0.921479847,1.553908355,-6.09310014,-7.246628754,-6.407827316,-4.290616417,-6.033911934,-6.486516281,-6.460641067,-6.974351762 -289,G39I,-0.146795925,-0.06749095,-0.017118722,-0.033975706,-0.672065611,-0.066558822,-0.085044732,-0.208547117,0.014665743,-0.04542732,-0.08955458,-0.007172792,-0.027064652,0.019291037,-0.087242448,-0.45840476,-0.885726462,0.966541471,1.557864593,-6.164445897,-6.177320816,-6.779677895,-4.94606192,-5.879094887,-7.040073967,-5.19630328,-4.449055163 -290,G39H,0.057380418,-0.031844157,-0.024760738,0.009028342,-0.053090858,-0.033920782,0.02622844,0.088532396,0.020842595,-0.026238516,-0.037449798,-0.04723196,-0.002289516,0.002937275,0.015119409,-0.000261691,-0.105920025,1.271519658,2.607809363,-0.519858377,-0.205048973,-1.792197647,0.474824692,0.109065681,-1.185935638,-2.002675836,-2.541995413 -291,G39K,-0.062437233,-0.068582407,-0.025821892,-0.019795206,-0.058406355,-0.040259006,0.034325895,-0.15920036,0.017189466,-0.085758201,-0.051406613,-0.007031838,-0.044611946,-0.033597508,-0.005992903,-0.024390306,-0.092422404,1.290710816,2.510587795,-0.190016757,-0.814647453,-1.333052483,1.27691851,1.339176514,-1.418478874,-1.314500354,-1.251868861 -292,G39M,0.024295061,-0.023338721,0.038627133,0.065037206,-0.157725137,-0.035261502,0.074765832,-0.02617571,0.158224393,-0.057586511,0.010909069,0.001256386,0.075997879,0.049841561,0.08023285,-0.133789397,-0.181660876,1.387012426,2.26346973,-5.676114206,-5.449192062,-5.720592445,-5.155404076,-5.699067833,-6.356314613,-4.884075391,-5.058667077 -293,G39L,0.013008287,-0.046049086,0.004741495,0.018861325,-0.179840624,-0.040992234,0.018079874,0.0079367,0.045538765,-0.00752326,-0.084574911,0.036195931,-0.026712942,0.029803871,0.007918778,-0.11534632,-0.244334927,1.457873556,2.38527137,-5.367090427,-5.132965263,-5.893771896,-4.691429237,-4.955336327,-6.161949409,-4.844458766,-5.120264332 -294,G39N,-0.066750461,-0.042494083,0.021690283,-0.013061568,-0.119873344,-0.067529727,0.01096705,-0.144467971,0.190629885,-0.033411321,-0.051576845,-0.003898685,0.047279251,-0.027336935,0.001213799,-0.045853334,-0.193893354,1.356320925,2.474560575,0.505353918,0.071031845,-0.110237968,0.91164846,1.684766953,-0.030439697,-0.82847736,-1.48990894 -295,G39Q,0.092318827,-0.024939292,0.040726235,0.043551306,-0.004546878,-0.004113926,0.064383847,0.120253807,0.115921951,-0.000718656,-0.049159927,0.035170699,0.046281771,0.033272204,0.053830408,0.013390614,-0.022484369,1.129608257,2.565841638,-0.461877621,-0.255409485,-1.376679962,0.569256279,0.57329216,-1.819847099,-2.290038971,-1.841318519 -296,G39P,-0.024957789,-0.023815928,-0.027370963,-1.121844931,-2.311613621,-0.010413806,0.00324641,-0.053161988,-0.020773369,-0.033664415,-0.013967441,-0.042311783,-0.012430143,-0.669808067,-1.573881794,-2.280075389,-2.343151853,1.731583608,1.314917237,-1.847444026,-0.902795815,-1.693601044,-1.355655121,-1.932642799,-3.352525352,-1.685002017,-1.355652664 -297,G39S,-0.002436374,-0.033435636,0.019670545,0.011983062,-0.054611988,0.011320493,0.041432215,-0.046304963,-0.077682494,-0.059012616,-0.007858656,0.03036699,0.008974099,-0.020358902,0.044325025,-0.020828144,-0.088395832,1.244729067,2.519156176,-0.96456564,-0.045579918,-1.325084709,-0.114295891,-1.408460999,-1.929406685,-1.640011587,-1.625222164 -298,G39R,0.035641591,-0.033352858,0.005775274,-0.003476574,-0.042271582,0.020859922,0.066997714,0.004285467,0.008114535,-0.058159105,-0.008546611,-0.013072561,0.024623108,-0.03597721,0.029024062,-0.031714287,-0.052828877,1.195261936,2.412936074,-1.525261711,-1.30752224,-2.627572128,-0.349559258,-0.996594505,-2.345060425,-2.464090906,-2.207126206 -299,G39T,-0.016386802,0.005647872,0.004195953,-0.003613952,-0.228329729,-0.019381087,0.058367178,-0.091140781,-0.010284957,-0.051187279,0.062483022,-0.005450593,0.013842499,-0.056765373,0.04953747,-0.195486475,-0.261172983,1.490739928,2.179379286,-2.804179903,-2.512974579,-2.897444412,-2.152659828,-3.012226082,-3.445594612,-2.919464024,-3.01860165 -300,G39W,-0.028442852,-0.009634091,0.022805716,0.027869203,-1.518050793,0.04987663,0.013734525,-0.070620228,0.096671626,-0.014407323,-0.004860859,0.003127785,0.042483646,-0.025102963,0.080841368,-1.222811367,-1.813290219,0.625418467,1.332678085,-5.778988435,-6.06773716,-4.958365845,-5.07958783,-5.640652596,-7.148598747,-5.718269943,-5.42346743 -301,G39V,-0.01442503,-0.019213564,-0.002205414,0.031149303,-0.193850581,0.004199489,0.015830909,-0.044680968,0.079504576,-0.012016053,-0.026411075,0.007491108,-0.011901935,0.018866093,0.043432513,-0.172887636,-0.214813525,1.474813867,2.236658008,-4.954182257,-4.526209999,-5.442019844,-3.551391846,-5.31167952,-5.939610077,-4.500919474,-4.311133515 -302,G39Y,0.020294346,-0.057338407,0.054551467,0.011123401,-0.821028526,-0.036919294,0.066726116,-0.026137424,-0.074542609,-0.054360603,-0.060316211,0.117057838,-0.007954905,0.009527161,0.012719641,-0.499111051,-1.142946,0.880813094,1.505869713,-5.663334793,-5.608340179,-5.750419746,-4.488738876,-6.196825729,-6.272349434,-6.708557884,-7.515189008 -303,A40C,-0.105117456,-0.058843793,-0.073506669,-0.010672742,-1.570195837,0.106651258,-0.075370656,-0.134864256,0.012803259,-0.029218284,-0.088469301,-0.0290485,-0.117964837,-0.009296999,-0.012048485,-1.492272613,-1.64811906,0.717687273,1.32311566,-9.076272589,-9.335064285,-8.492576012,-10.19004385,-7.921906654,-9.441772141,-5.2637627,-3.171816914 -304,A40E,-0.063069777,0.00224266,-0.022318402,-0.570752814,-1.945210291,-0.01115715,-0.031995033,-0.094144521,0.000754269,0.023306201,-0.018820882,-0.024049865,-0.020586939,-0.300689456,-0.840816172,-2.088340444,-1.802080138,1.360774921,1.321849991,-8.268409337,-7.952552399,-8.905314232,-7.445812538,-7.368665733,-9.669701782,-5.624080508,-4.453475657 -305,A40D,-0.05477293,0.005328475,-0.074927373,-0.558253547,-2.183416924,0.016838642,-0.057307363,-0.052238496,-0.042208472,0.029860412,-0.019203462,-0.082346915,-0.06750783,-0.33490974,-0.781597353,-1.978736647,-2.3880972,1.484087322,1.353628589,-9.115126808,-9.163704842,-9.302482513,-8.422225395,-8.19860421,-10.48861708,-6.013749868,-5.155753834 -306,A40G,-0.022685054,0.004718077,-0.044784395,0.015946554,0.036494768,0.07070687,-0.027993855,-0.017376252,0.012355061,-0.014622848,0.024059001,-0.030248334,-0.059320455,0.036542207,-0.0046491,0.053630682,0.019358853,1.096133949,2.600588944,-0.157101077,-0.468017731,-0.370095764,-0.025973915,-0.015459946,0.094041969,-1.312565006,0.545511907 -307,A40F,-0.103653369,-0.03218484,-0.066587457,-1.287011271,-2.38393397,-0.002454684,-0.074610804,-0.132695933,0.121574302,0.021951617,-0.086321296,-0.05502172,-0.078153194,-0.875162581,-1.69885996,-1.996110743,-2.771757196,2.128698785,1.51933801,-11.64279599,-12.05313537,-10.62418295,-15.23865742,-10.27326093,-10.02474327,-5.943542714,-3.972397033 -308,A40I,-0.094116576,-0.016606757,-0.023440445,-0.419960007,-1.756061106,-0.027451167,-0.09981725,-0.088415901,0.232006767,-0.048122929,0.014909415,-0.083618016,0.036737127,-0.289957244,-0.549962769,-1.878266823,-1.633855389,1.398543463,1.356202295,-9.896002504,-11.21368596,-9.155639023,-11.12650687,-7.659156036,-10.32502463,-5.093383976,-3.349739284 -309,A40H,-0.038118501,0.015070941,-0.037597731,-1.411975743,-2.788829598,0.000639644,-0.030914637,-0.045322365,-0.019298419,0.003121459,0.027020422,-0.063391787,-0.011803675,-0.802521851,-2.021429634,-2.386422312,-3.191236883,1.782119063,1.264502866,-11.03103163,-11.40243981,-11.17949748,-11.79677647,-9.29396254,-11.48248183,-6.857150458,-5.841770338 -310,A40K,-0.093801117,0.002298994,-0.155132471,-1.65717812,-2.764567772,0.049789712,-0.047072531,-0.140529703,0.07926064,-0.008597839,0.013195827,-0.053988032,-0.25627691,-1.137884574,-2.176471666,-2.659977884,-2.86915766,0.701938127,0.734855649,-9.688825706,-10.28332585,-9.40587561,-10.43470382,-7.870976143,-10.44924711,-6.196180974,-4.554303697 -311,A40M,-0.033500351,-0.014801061,-0.04989851,-0.022023066,-1.027279569,0.026258481,-0.012748255,-0.054252446,0.082907491,-0.064487197,0.034885075,-0.084805631,-0.014991388,-0.033325444,-0.010720688,-0.740214699,-1.314344438,0.756267169,1.407117765,-9.717348703,-10.64748917,-9.038460899,-11.74316519,-8.140702957,-9.016925301,-5.942501655,-5.028209159 -312,A40L,-0.035231611,-0.010382304,-0.060243123,-0.376854516,-1.977678207,-0.05162157,-0.041155282,-0.02930794,-0.03724315,-0.008569522,-0.012195085,-0.097916445,-0.022569801,-0.198981991,-0.554727041,-2.008126796,-1.947229617,1.363273356,1.336924195,-9.107283621,-9.785855507,-8.010775436,-11.31403778,-7.249760803,-9.175988579,-4.965379495,-1.602838039 -313,A40N,-0.071405342,-0.053581252,-0.133728755,-0.040425194,-1.691389934,0.009492687,-0.116351687,-0.026458996,-0.079912859,-0.122423627,0.015261124,-0.223380528,-0.044076981,-0.078624613,-0.002225775,-1.697627936,-1.685151932,0.980475356,1.329809824,-9.744348193,-10.28625108,-8.746045074,-10.45251505,-8.457188736,-10.77974103,-6.111152576,-4.520367236 -314,A40Q,-0.053653174,-0.007756886,-0.03961109,-0.036845682,-0.538026022,0.006859272,-0.04486314,-0.062443208,-0.074541658,-0.000211073,-0.015302698,-0.028539833,-0.050682347,-0.007673269,-0.066018094,-0.37028403,-0.705768013,0.968251039,1.610034084,-9.733010066,-10.40476114,-9.48382283,-10.2149325,-8.156155273,-10.40537859,-6.305973184,-5.44235615 -315,A40P,-0.07962617,-0.034216582,-0.460880511,-1.878046819,-2.675154675,-0.01378096,-0.062021519,-0.097230821,-0.02543906,-0.041674732,-0.026758432,-0.335497833,-0.586263189,-1.695279206,-2.060814432,-2.35490038,-2.99540897,1.469623919,0.776240657,-9.377176689,-9.265714676,-9.840518715,-9.610538567,-7.831010452,-10.33810104,-6.788661963,-5.546441044 -316,A40S,-0.06026332,-0.017610296,-0.066653575,-0.015269671,-0.15070486,0.016593883,-0.064965621,-0.055561019,-0.002819204,-0.001710085,-0.033510507,-0.055722437,-0.077584712,0.020832589,-0.05137193,-0.100199099,-0.201210621,1.250644771,2.261861384,-5.264974377,-5.080157265,-4.909791092,-5.498686325,-4.608633636,-6.227603569,-4.436118249,-3.761126163 -317,A40R,-0.092813762,-0.008191595,-0.37600203,-1.83979727,-2.49902172,0.036859048,-0.06776038,-0.117867144,0.000722387,-0.010637049,-0.005746141,-0.299719432,-0.452284627,-1.475891414,-2.203703125,-2.43264754,-2.5653959,1.568285453,0.86188763,-9.219595868,-10.81506764,-10.7152078,-9.241713127,-6.798023094,-8.527967674,-4.636907077,-4.139446339 -318,A40T,-0.060567583,-0.00658904,-0.065936878,0.008830971,-0.474438292,0.032575306,-0.065806562,-0.055328603,0.013220432,-0.008632732,-0.004545347,-0.084649827,-0.047223928,0.010730045,0.006931896,-0.372457896,-0.576418687,1.584388803,2.034189763,-6.061827898,-6.02127092,-6.374774521,-6.46300911,-5.088188705,-6.361896233,-4.341103514,-3.264619475 -319,A40W,-0.086372996,0.034520409,-0.066124692,-0.3816922,-1.923133717,0.053237823,-0.060273583,-0.112472409,0.028829628,0.006846049,0.062194768,-0.090718098,-0.041531285,-0.225016437,-0.538367963,-1.817690822,-2.028576611,1.369619487,1.363487402,-9.56096591,-9.665654472,-8.352868759,-12.55354668,-7.67288636,-9.559873283,-5.210615845,-4.674515845 -320,A40V,-0.028467917,0.012072437,-0.034846281,0.011812778,-1.766813589,-0.002176936,-0.021491331,-0.035444503,0.017451831,0.02022624,0.003918633,-0.043448358,-0.026244204,0.062826097,-0.039200542,-1.531854271,-2.001772906,0.620901931,1.315117069,-7.295956834,-8.534280052,-6.822046333,-8.301037498,-6.192158562,-6.630261726,-3.547302239,-1.71421689 -321,A40Y,0.016384013,-0.002946518,0.029702202,-1.492155119,-2.342321982,0.049562407,0.04584061,-0.013072585,-0.007219844,-0.00249084,-0.003402196,-0.010566462,0.069970865,-1.09567298,-1.888637257,-2.024139467,-2.660504497,2.277840302,1.555949434,-12.55424095,-12.88309465,-11.62149262,-15.76607797,-11.04554511,-11.45499439,-6.028284081,-4.387712206 -322,R41A,0.014175223,0.001135033,-0.005289116,-0.016504862,-0.329086585,-0.024127067,0.0281689,0.000181545,-0.000805686,0.013836642,-0.011566576,0.026436758,-0.03701499,0.016264429,-0.049274152,-0.247487004,-0.410686165,1.075702019,1.803135478,-7.911033533,-8.454929474,-7.594357742,-8.198534317,-6.476770332,-8.830575798,-6.496754075,-3.516781603 -323,R41C,0.036169782,0.038635089,0.014229369,-0.348469811,-1.693509349,0.013772578,0.076069142,-0.003729578,0.107267498,0.003083749,0.074186428,0.001910194,0.026548544,-0.161939826,-0.534999795,-1.654782867,-1.73223583,0.995172686,1.3341927,-10.90790401,-11.80925703,-10.84698395,-11.5463815,-9.791303535,-10.54559406,-10.07774203,-9.472095529 -324,R41E,0.026797447,-0.143173155,-0.006802989,0.112049327,-1.883635418,-0.175888697,0.076386644,-0.022791751,-0.304943142,-0.097306448,-0.189039861,0.008005655,-0.021611632,0.143802943,0.080295711,-1.76744391,-1.999826925,0.582131696,1.303941543,-7.229512218,-8.779807655,-7.426165421,-7.652133904,-5.51179612,-6.77765799,-5.996768207,-2.101125874 -325,R41D,0.001148473,0.034898487,0.031915898,0.011613871,-1.955265097,-0.055899153,0.026722857,-0.024425912,0.045136251,0.026786535,0.043010439,0.053678644,0.010153152,0.06180162,-0.038573879,-1.63579779,-2.274732404,0.554420618,1.308223206,-7.130674689,-9.39888298,-7.688447708,-7.349585938,-4.913296463,-6.303160355,-5.369035478,-2.072761667 -326,R41G,-0.045227413,-0.008654291,-0.013518429,-0.272394316,-1.974678812,-0.005760957,-0.015736165,-0.074718661,-0.011328907,-0.017192074,-0.000116507,-0.012607344,-0.014429513,-0.174756392,-0.370032239,-1.870903855,-2.078453769,1.113777737,1.325451707,-8.174043091,-8.158225319,-8.015790512,-8.991767075,-7.331984467,-8.372448082,-6.738433802,-4.347049413 -327,R41F,-0.031995134,-0.066353486,0.024488763,-0.021359166,-1.159161857,-0.023862403,-0.043594107,-0.020396161,0.215558843,-0.057574732,-0.07513224,-0.005845457,0.054822983,-0.073462555,0.030744224,-0.878205035,-1.440118679,1.015772328,1.437340451,-9.044889124,-9.681272629,-9.217082642,-9.704488426,-7.416704666,-9.204897255,-7.12170323,-4.546142434 -328,R41I,0.051475338,0.056238444,0.07226571,0.015032337,-0.608879904,-0.080332022,0.044943208,0.058007467,0.066192163,0.017147786,0.095329102,0.02071762,0.1238138,0.029124832,0.000939842,-0.382953871,-0.834805937,0.684508662,1.478960912,-7.823989711,-8.081413071,-8.274350647,-9.372880371,-5.779226883,-7.612077583,-6.078301101,-3.407516335 -329,R41H,0.024153756,0.007820113,0.030577838,0.025247472,0.021122042,-0.042750288,0.033308045,0.014999467,-0.001452547,0.020375901,-0.004735675,0.077694404,-0.016538728,0.023690038,0.026804905,0.032541371,0.009702712,1.33983753,2.954958155,-4.14439126,-4.866262558,-4.056394279,-4.957537155,-3.732292458,-3.109469849,-5.080128381,-2.843845546 -330,R41K,0.071745051,0.129526415,-0.065812197,-0.092824461,-0.157427045,-0.15066343,0.014729743,0.128760359,0.186418552,0.075180687,0.183872142,0.020970632,-0.152595025,-0.209343603,0.023694682,-0.008119517,-0.306734572,1.304766772,2.428468314,-4.021878604,-4.007838219,-3.941798958,-5.133931519,-3.067459198,-3.958365128,-3.127525866,-1.831786823 -331,R41M,-0.042544174,0.050165097,0.046365118,-0.019561203,-0.282237032,-0.267229854,-0.05925031,-0.025838037,-0.165445685,0.043144455,0.057185739,0.121949007,-0.029218772,0.036169064,-0.075291469,-0.156783747,-0.407690316,1.209663148,2.069648807,-9.12365246,-9.249342278,-9.344493996,-10.27675532,-7.339047104,-9.408623604,-7.491713806,-5.155772824 -332,R41L,0.028565672,0.012327097,0.000829758,0.009176213,-0.342520526,-0.022229294,0.048534741,0.008596603,0.022134969,0.02566173,-0.001007536,0.020678276,-0.01901876,0.013369368,0.004983057,-0.285093629,-0.399947422,1.043328142,1.737125127,-7.594377237,-7.865121719,-8.056239372,-8.804315979,-5.399986244,-7.84622287,-6.203619382,-3.71831129 -333,R41N,0.045318359,0.041106422,0.052936364,-0.001832782,-0.225044473,-0.028365495,0.046641428,0.04399529,-0.050198333,0.024554901,0.057657943,0.005892296,0.099980431,-0.009939939,0.006274376,-0.205555551,-0.244533394,1.354411976,2.071730656,-7.147413536,-8.834672752,-6.638065598,-8.063551537,-6.002389236,-6.198388557,-6.067181409,-2.957229038 -334,R41Q,0.079704802,-0.032338335,-0.004277411,-0.009874873,-0.280324444,-0.02242655,0.128997316,0.030412288,0.079645356,-0.130581243,0.065904574,-0.005870749,-0.002684073,-0.094267144,0.074517398,-0.291964603,-0.268684284,1.725405224,2.288258949,-5.176583997,-6.375551888,-5.012243416,-5.651072571,-4.208332008,-4.6357201,-5.491668112,-2.406481727 -335,R41P,-0.005156844,-0.013415779,0.004111326,-0.003349481,-0.099713743,-0.042323383,-0.002951166,-0.007362521,-0.018683797,0.002332838,-0.029164396,0.031672386,-0.023449735,0.025787403,-0.032486364,-0.071686803,-0.127740683,1.433914808,2.585515661,-8.540180766,-8.880432442,-8.313068787,-8.920650368,-7.153762436,-9.4329898,-7.461681698,-4.917740662 -336,R41S,-0.010113505,0.02803689,0.017323919,0.017152012,-0.309092945,-0.028761483,0.007218868,-0.027445878,0.049795038,0.045346296,0.010727483,0.038479689,-0.003831852,0.053735448,-0.019431425,-0.209490954,-0.408694936,1.177655861,1.972001253,-6.728092082,-7.8853937,-6.289473663,-6.690786934,-5.698657974,-7.07614814,-5.612795017,-2.758965204 -337,R41T,0.005292563,-0.010290918,0.030309218,-0.037575382,-0.286286649,-0.018796609,0.020895518,-0.010310393,0.04570781,-0.02191123,0.001329394,0.04627892,0.014339515,-0.024637909,-0.050512854,-0.224187223,-0.348386074,1.320921124,1.996132372,-5.357786441,-6.790398979,-4.410879402,-5.857380142,-3.788015831,-5.942257851,-4.363698391,-1.135423417 -338,R41W,0.123407561,-0.154043473,-0.085805557,-0.114650878,-2.024107135,-0.07270929,0.069578411,0.177236711,-0.010752571,-0.207319507,-0.100767438,-0.128214092,-0.043397021,-0.202713025,-0.02658873,-2.103236012,-1.944978257,1.279642933,1.31631113,-9.193398578,-10.30094853,-9.016841087,-9.764631874,-8.5371091,-8.347462296,-8.291228436,-6.660180437 -339,R41V,-0.046817501,0.004022583,0.020972943,0.011967721,-0.491868623,-0.000111315,-0.044483977,-0.049151024,0.049013095,0.010506042,-0.002460877,0.043824623,-0.001878738,0.066066778,-0.042131336,-0.307287876,-0.67644937,0.893857744,1.61357601,-6.939408635,-7.161310951,-7.224706398,-8.14816021,-5.267458839,-6.895406776,-5.922715871,-2.604440072 -340,R41Y,0.030734586,0.03998636,0.031102226,0.04914011,-0.608998027,-0.007637756,0.032034601,0.02943457,0.010842043,-0.021172895,0.101145615,0.042253499,0.019950953,0.037836224,0.060443996,-0.501176021,-0.716820033,0.57128907,1.408408709,-8.450557805,-8.96179113,-9.236753685,-9.369793518,-7.415555893,-7.268894798,-6.553774327,-5.110849356 -341,V42A,-0.048834558,-0.054367771,-0.020670072,-0.066569947,-1.919095692,0.001026984,-0.075822649,-0.021846467,0.037153859,-0.067905561,-0.04082998,-0.034508999,-0.006831145,-0.00888129,-0.124258604,-1.766112117,-2.072079266,0.754085873,1.310172393,-5.750713779,-5.368870941,-4.986166008,-5.493981499,-4.625452965,-8.279097481,-5.589696845,-1.666565086 -342,V42C,-0.016306958,-0.010139181,0.027446027,-0.022494841,-1.543953069,-0.110357639,-0.092530132,0.059916217,0.056092172,-0.067245685,0.046967324,0.01205723,0.042834824,0.074412597,-0.119402279,-1.723968477,-1.363937661,0.717562409,1.310414273,-11.24883848,-10.2872723,-11.55317311,-12.45897812,-9.921269753,-12.02349913,-8.131286207,-4.247702166 -343,V42E,-0.117452332,-1.014123925,-2.410592422,-2.697324166,-2.394525721,0.067267081,-0.122491932,-0.112412732,-0.04302231,-0.927745342,-1.100502508,-2.444708228,-2.376476615,-2.501435853,-2.893212478,-2.256454649,-2.532596793,0.57738801,-0.603679795,-13.28097255,-12.11638589,-12.71482513,-13.80879637,-11.11338464,-16.6514707,-9.730004057,-6.711900429 -344,V42D,-0.127822416,-1.305537714,-2.147604355,-2.434336099,-2.884112643,0.037513529,-0.125833267,-0.129811565,-0.053346499,-1.267758217,-1.343317211,-2.123075422,-2.172133287,-1.878773051,-2.989899146,-2.837911829,-2.930313456,3.527073422,1.237057634,-14.22170071,-12.82961925,-13.59708347,-15.42674113,-11.75541148,-17.4996482,-9.590015922,-6.711900429 -345,V42G,-0.073093496,-0.251672928,-1.463480316,-2.078746494,-1.921353464,-0.004579938,-0.069322555,-0.076864437,-0.025710458,-0.157240227,-0.346105629,-1.536847106,-1.390113525,-2.420574549,-1.736918438,-2.622751376,-1.219955552,1.012322504,0.057985491,-12.13901232,-11.28409974,-12.17010969,-13.26162738,-9.293472969,-14.68575185,-7.179026853,-1.359385682 -346,V42F,-0.109596985,-0.152504425,-0.059699559,-0.097575803,-0.057509392,-0.031474665,-0.164588828,-0.054605142,-0.062326592,-0.227243782,-0.077765067,-0.026609581,-0.092789536,-0.060107365,-0.135044241,-0.104991159,-0.010027625,1.355218569,2.286084772,-8.167220334,-6.880758537,-8.669246216,-9.637797974,-8.584950974,-7.063347969,-5.451060126,-1.854021945 -347,V42I,-0.008769621,-0.041817101,-0.059958037,-0.089884691,-0.201484743,-0.113389739,-0.091190361,0.073651119,0.060683168,-0.0945148,0.010880598,-0.099594326,-0.020321747,-0.042378598,-0.137390783,-0.180962278,-0.222007208,1.595464392,2.286032838,-1.45597131,-1.299195236,-1.827370583,-0.728633652,-2.280871422,-1.14378566,-2.709295143,-0.430015489 -348,V42H,-0.095633241,-0.077905631,-0.662117764,-2.025909271,-2.563731445,-0.032851672,-0.134606227,-0.056660255,0.050092344,-0.110330373,-0.045480889,-0.54762758,-0.776607948,-1.789991781,-2.26182676,-2.402343074,-2.725119816,1.847976124,0.864868008,-14.14067017,-13.3132382,-12.76463396,-15.27925266,-11.57984059,-17.76638544,-8.762214041,-5.51012779 -349,V42K,-0.076907735,-1.086399835,-2.316118179,-2.452334925,-2.601081474,-0.076715539,-0.112720561,-0.041094909,-0.002590601,-0.982092621,-1.190707048,-2.186744502,-2.445491856,-2.243472126,-2.661197724,-2.600550914,-2.601612034,0.584600842,-0.61795067,-12.3862076,-11.57915673,-10.83522979,-12.07693784,-10.42470998,-17.01500368,-8.226119872,-4.937671666 -350,V42M,-0.085184112,0.025537308,0.013050768,-0.0322342,-0.099695113,-0.044139457,-0.117065315,-0.053302909,0.041422846,0.072241858,-0.021167243,-0.011886325,0.037987861,0.02924951,-0.09371791,-0.064587843,-0.134802382,1.278720416,2.428647026,-8.580666524,-6.122465477,-8.733184319,-8.781018852,-9.204126373,-10.0625376,-6.257280428,-3.232121047 -351,V42L,-0.073064142,-0.071597376,-0.068221677,-0.056173158,-0.143120966,-0.093797913,-0.119408857,-0.026719426,0.039146222,-0.057165336,-0.086029415,-0.037557869,-0.098885484,0.02185562,-0.134201936,-0.095157714,-0.191084217,1.210472728,2.210855545,-5.410240579,-2.876225922,-5.385057892,-5.770379646,-6.67588121,-6.343658226,-4.820620695,0.251478343 -352,V42N,-0.021236026,-0.029316436,-0.127444829,-1.244736528,-2.725804065,-0.044934684,-0.036450231,-0.00602182,0.047244802,-0.093928312,0.035295441,-0.171475394,-0.083414264,-0.732058527,-1.757414529,-2.712386604,-2.739221525,1.250531157,0.955906819,-13.83500946,-12.65718384,-14.47535558,-14.17697746,-10.85414404,-17.01138639,-8.415453989,-4.527639932 -353,V42Q,-0.138643744,-0.297253804,-1.702056729,-2.659999813,-2.720700732,0.014348893,-0.166878043,-0.110409444,-0.041392685,-0.212204467,-0.382303141,-1.471458408,-1.932655049,-2.268548722,-3.051450904,-2.44953625,-2.991865214,1.250958046,0.116424931,-12.44468009,-10.96726592,-11.74995643,-12.20772287,-10.64473772,-16.65371751,-8.487173463,-5.157868608 -354,V42P,-0.074100851,-1.450113453,-2.103837742,-2.380697457,-3.330474001,-0.017304509,-0.106523379,-0.041678322,-0.032663874,-1.440946745,-1.459280161,-2.135852895,-2.071822589,-2.220609243,-2.540785671,-2.79953678,-3.861411222,-0.035027696,-0.897457807,-11.63433995,-11.34192043,-10.60614514,-11.55235542,-10.25729943,-14.41397932,-7.41640401,-2.364376123 -355,V42S,-0.11661343,-0.080188993,-0.301495143,-1.842300377,-2.10528659,-0.000481122,-0.148309415,-0.084917444,-0.079401868,-0.066693012,-0.093684974,-0.300127693,-0.302862592,-1.437678511,-2.246922242,-2.057998733,-2.152574446,2.796002436,1.799131787,-10.11553294,-9.464000038,-9.996746544,-10.66503382,-8.015808113,-12.4360762,-7.245395211,-3.894109901 -356,V42R,-0.064301108,-1.301568907,-2.06483162,-2.205821026,-2.541797031,0.00557498,-0.098159752,-0.030442463,-0.041392685,-1.365721917,-1.237415896,-2.044947863,-2.084715377,-2.226614224,-2.185027827,-3.060814266,-2.022779795,0.226432034,-0.811148775,-13.38400421,-11.10321332,-12.44210976,-13.50770814,-10.85702736,-19.00996249,-8.845569055,-6.055786783 -357,V42T,-0.076838235,-0.047996938,-0.03088769,-0.05184063,-1.804800391,0.000422425,-0.093293286,-0.060383184,0.171710638,-0.049903321,-0.046090554,-0.039315214,-0.022460166,0.015879105,-0.119560364,-1.556925347,-2.052675435,0.638661461,1.315258182,-8.216012994,-8.130946434,-7.172704544,-8.420498749,-6.613806557,-10.74210869,-6.494612137,-2.412657332 -358,V42W,-0.037367618,-0.062087257,-0.012738049,-0.029497987,-0.748041039,-0.077508068,-0.106629469,0.031894233,0.190215902,-0.027850112,-0.096324401,-0.034456157,0.008980059,0.035281475,-0.094277448,-0.609324838,-0.886757239,0.691407063,1.409141109,-12.54632902,-11.01480553,-11.77137137,-13.93374648,-11.03126887,-14.98045285,-7.133334924,-2.915912394 -359,V42Y,-0.100230453,-0.083763121,-0.140420345,-0.112904749,-1.576655735,-0.052675856,-0.156794085,-0.04366682,-0.02208753,-0.041996571,-0.125529671,-0.122374961,-0.158465729,0.100316262,-0.32612576,-1.946958606,-1.206352864,0.545766663,1.295458651,-11.60412526,-11.02745354,-11.49822708,-13.49940833,-10.31264599,-11.68289134,-7.77055538,-1.747340932 -360,G43A,-0.010556268,0.018114292,-0.01299378,-0.027215972,-1.171754763,-0.019636857,-0.004146897,-0.016965639,-0.042451105,-0.033158722,0.069387306,-0.024616205,-0.001371355,-0.045120507,-0.009311437,-0.825654066,-1.517855459,1.19388807,1.510562707,-8.305482494,-8.844026169,-7.229489586,-9.348851646,-9.032743431,-7.072301636,-5.308879032,-2.424908077 -361,G43C,-0.079963376,0.005204986,-0.556814425,-1.795016112,-2.695473786,0.067136271,-0.061502195,-0.098424557,-0.028688526,-0.022773292,0.033183264,-0.377130372,-0.736498477,-1.494415988,-2.095616235,-2.367148769,-3.023798802,1.64219998,0.885153842,-10.22108136,-11.22729279,-8.533606812,-10.73346894,-9.758839691,-10.85219858,-6.64903826,-4.61918005 -362,G43E,-0.063096545,-1.523835756,-2.305738553,-2.228948903,-2.814362219,0.023195865,-0.051892533,-0.074300557,-0.104480941,-1.374654321,-1.67301719,-2.189533394,-2.421943711,-1.984599716,-2.47329809,-2.431363764,-3.197360674,0.293820534,-0.857723334,-13.75971575,-14.16470794,-13.16658147,-14.91205823,-12.94175538,-13.61347571,-8.138438834,-6.28505637 -363,G43D,-0.035579313,-1.308985898,-2.552514988,-2.32521034,-2.734532397,-0.019801497,-0.023699284,-0.047459342,-0.163089127,-1.48983322,-1.128138576,-2.55335422,-2.551675755,-1.950480533,-2.699940147,-2.443002072,-3.026062722,0.248831337,-1.063040398,-15.17983752,-15.56843794,-15.6326565,-15.58917384,-14.22829707,-14.88062227,-10.41556539,-10.13728232 -364,G43F,0.008573815,-0.8487223,-2.252041548,-2.675251899,-2.973649581,0.088505553,0.032188896,-0.015041267,0.082955672,-0.71298812,-0.98445648,-2.280613864,-2.223469232,-2.376710181,-2.973793616,-2.948412966,-2.998886196,0.374740526,-0.553456275,-15.1100951,-16.72568621,-15.84018517,-15.40007823,-13.21064915,-14.37387673,-7.646789435,-4.426916876 -365,G43I,-0.016930748,-1.301420144,-1.757612138,-2.442261861,-2.97922017,-0.015234464,-0.022679447,-0.011182049,-0.14729486,-1.354036556,-1.248803731,-1.655796722,-1.859427553,-2.177861771,-2.70666195,-2.925655815,-3.032784525,3.353022908,1.148274499,-17.55281205,-18.06876511,-18.82870093,-18.24917424,-15.5159438,-17.10147619,-10.47188074,-10.31466836 -366,G43H,-0.017279964,-1.446754015,-2.094197529,-2.337896907,-2.937324586,0.032580747,0.008006811,-0.042566739,-0.156249703,-1.255750014,-1.637758016,-2.183051267,-2.00534379,-2.279147584,-2.39664623,-2.850850369,-3.023798802,0.743142448,-0.725932108,-13.6477212,-15.38191731,-14.16540439,-13.30923399,-12.44064476,-12.94140556,-7.236583262,-4.60622181 -367,G43K,-0.081894555,-1.527198427,-2.361468899,-2.483649254,-3.171122562,-0.012630415,-0.045896812,-0.117892297,-0.052638586,-1.310823958,-1.743572896,-2.230438382,-2.492499416,-2.201595963,-2.765702545,-3.074328743,-3.26791638,0.471716662,-0.7914997,-14.73169277,-15.9936355,-14.43238011,-15.44536844,-13.76628203,-14.02079778,-8.359684764,-6.499039112 -368,G43M,0.013589131,-1.224458034,-2.278992232,-2.401172587,-3.026176526,0.017405336,0.0464152,-0.019236939,-0.082752623,-1.1320756,-1.316840467,-2.294728073,-2.263256391,-2.566915649,-2.235429524,-2.837588438,-3.214764613,0.64600267,-0.680544662,-15.70775851,-16.42395145,-16.03231233,-18.06882285,-13.71296685,-14.30073907,-9.130346524,-7.189066379 -369,G43L,-0.054140074,-1.212846133,-2.325670353,-2.737265782,-3.575254088,0.001630185,-0.041433008,-0.06684714,-0.108203337,-1.104018101,-1.321674164,-2.27668357,-2.374657135,-2.31478794,-3.159743624,-3.488550717,-3.661957459,0.711939961,-0.655279386,-16.25556056,-16.9073942,-16.38049994,-17.86799541,-14.43660992,-15.68530334,-8.650885915,-6.350141629 -370,G43N,-0.036299714,-1.39928115,-2.081234563,-2.675656253,-2.934463313,0.006664864,-0.018961927,-0.053637501,-0.166814064,-1.632810823,-1.165751477,-2.427486511,-1.734982614,-2.824612823,-2.526699682,-2.618164358,-3.250762267,-0.07679628,-1.106848059,-13.86738216,-15.78238918,-13.52849535,-13.71421355,-12.11440718,-14.19740553,-8.326077533,-6.143917468 -371,G43Q,-0.041755758,-1.234980317,-2.259884534,-2.683094885,-2.981492567,0.020733279,-0.035094436,-0.04841708,-0.140367317,-1.288750274,-1.181210359,-1.915021531,-2.604747537,-2.61317784,-2.753011929,-2.883850629,-3.079134505,2.430715184,0.184737904,-13.73389587,-14.81988088,-13.49472028,-14.32991122,-12.37068157,-13.65428542,-7.841259303,-5.190785441 -372,G43P,-0.032452791,-1.572854555,-2.132032543,-2.520256271,-3.090687976,-0.004283567,-0.029746622,-0.035158959,-0.116389154,-1.580112654,-1.565596456,-2.131750293,-2.132314792,-2.424141255,-2.616371286,-2.761760834,-3.419615117,-0.019045775,-1.037995266,-15.60811012,-16.21856866,-15.28665533,-16.39593468,-14.96997552,-15.16941643,-10.47188074,-10.31466851 -373,G43S,-0.013414771,0.031663285,-0.0031158,-0.023933613,-1.823495968,-0.046129331,-0.022707835,-0.004121706,-0.01117313,-0.007488021,0.07081459,-0.032337035,0.026105435,-0.023249118,-0.024618107,-1.492438013,-2.154553923,0.92565475,1.340169118,-8.99387086,-10.34149201,-7.51783535,-9.397020958,-7.875210609,-9.837795372,-5.910335861,-1.999869568 -374,G43R,-0.01653941,-1.573510556,-2.240215478,-2.427562716,-2.774415405,0.005823463,0.009177201,-0.04225602,-0.139328151,-1.582519915,-1.564501197,-2.069216747,-2.411214208,-2.517495582,-2.33762985,-2.788168371,-2.760662439,0.043870567,-1.047244703,-13.05476638,-14.41069417,-13.30337405,-13.63183779,-12.33035453,-11.59757134,-7.166468377,-4.238394326 -375,G43T,-0.042480481,-0.214801142,-1.569704804,-2.226703123,-3.294010353,0.01581254,-0.022802656,-0.062158306,-0.081870518,-0.170295825,-0.259306459,-1.459545704,-1.679863904,-2.333793272,-2.119612974,-3.081587316,-3.50643339,1.142438277,0.095072728,-11.98996554,-13.17248901,-11.64800413,-12.87892946,-10.67888241,-11.57152271,-7.154128703,-4.912868137 -376,G43W,-0.017646739,-1.282892397,-2.472765099,-2.168009471,-2.926816531,0.0464377,-0.021616775,-0.013676703,-0.091447217,-1.145597199,-1.420187594,-2.738627523,-2.206902675,-2.135753835,-2.200265107,-2.628275374,-3.225357687,0.537608707,-0.705191738,-15.02642581,-14.3611811,-15.04275898,-16.04705257,-14.3695112,-15.3116252,-7.375283427,-3.516243648 -377,G43V,-0.045673358,-1.25684123,-2.068467838,-2.51237453,-2.921696588,-0.007825116,-0.041632158,-0.049714557,-0.096451403,-1.232059266,-1.281623194,-2.009475948,-2.127459727,-2.14696495,-2.87778411,-2.338456494,-3.504936681,3.884151605,1.615616804,-15.79596283,-16.1755331,-16.91849915,-17.07108961,-14.5564424,-14.25824988,-9.053022884,-7.123456681 -378,G43Y,-0.00396217,-0.968048925,-2.584198589,-2.467818316,-3.092822255,-0.036679704,0.034221808,-0.042146147,-0.055376793,-0.71168197,-1.22441588,-2.157266216,-3.011130961,-2.253362533,-2.682274098,-3.001156577,-3.184487933,0.954184698,-0.440632812,-15.93702095,-17.3521134,-16.64099828,-15.51975657,-13.93598613,-16.23625039,-8.09764078,-5.990049015 -379,Y44A,-0.032056769,-0.037020995,-0.71736319,-1.991257032,-2.982065641,0.065134491,-0.00799999,-0.056113548,-0.077073734,-0.063749276,-0.010292713,-0.401736261,-1.032990119,-1.859973752,-2.122540311,-2.528732496,-3.435398786,1.582342897,0.76753041,-5.200916205,-6.367536705,-6.534333023,-3.168577011,-4.196208145,-5.73792614,-4.030029364,1.261619069 -380,Y44C,0.005731835,-0.027246875,-0.963401219,-2.117774895,-3.081494016,0.056076272,0.064422019,-0.052958349,-0.032848122,-0.025188492,-0.029305257,-0.845412157,-1.081390281,-2.083577156,-2.151972634,-2.788333553,-3.374654478,1.958907606,0.771965128,-7.681247687,-7.874620438,-8.790595512,-5.928133461,-7.69243821,-8.120450813,-6.742638616,-2.284247111 -381,Y44E,-0.031477692,-0.354135011,-1.616983297,-2.625848473,-2.970126549,0.08393912,0.001397176,-0.06435256,-0.020314853,-0.248172896,-0.460097126,-1.521909042,-1.712057551,-2.626180462,-2.625516484,-2.904968127,-3.035284971,1.235635815,0.093376852,-10.07004825,-10.2249962,-10.88807263,-8.534778046,-9.787725784,-10.91466857,-8.720518431,-6.437688822 -382,Y44D,0.00851447,-1.465348139,-1.960738831,-2.202047407,-2.569204228,0.055964628,0.02364877,-0.00661983,-0.167029162,-1.580020821,-1.350675457,-1.776995195,-2.144482466,-2.279206624,-2.124888189,-2.381903029,-2.756505426,0.433350276,-0.977539294,-10.53742591,-10.31608683,-11.64558296,-8.708262283,-10.31205057,-11.7051469,-8.720518431,-6.437688822 -383,Y44G,-0.00615611,-0.061174353,-1.161942904,-2.310945467,-3.025105581,0.059040801,0.032595772,-0.044907992,-0.065655589,-0.018007045,-0.10434166,-0.92454909,-1.399336717,-2.180428675,-2.441462259,-2.815763663,-3.234447498,1.920225155,0.699607688,-9.475370552,-9.335515411,-10.88684491,-7.60013411,-8.74976976,-10.80458857,-7.070268663,-2.45768412 -384,Y44F,0.041897981,0.020924838,-0.016223451,-0.000779071,-0.040809435,-0.013767384,0.048343202,0.035452759,-0.010164613,0.014771704,0.027077971,-0.035604873,0.003157972,-0.07259427,0.071036128,-0.082826713,0.001207843,1.38895447,2.334282891,-1.930168349,-2.346116386,-2.289870163,-1.70944101,-2.037169846,-1.268244339,-3.87037683,1.369691373 -385,Y44I,0.016883048,0.012810142,0.02749229,-0.001490999,-1.736939019,-0.002348038,0.050895873,-0.017129778,-0.093440265,0.010239244,0.01538104,-0.012992684,0.067977264,-0.086359831,0.083377834,-1.452297671,-2.021580367,0.947951862,1.346617629,-3.426127701,-2.943506485,-2.235793022,-4.714617218,-4.828631165,-2.408090614,-3.648212274,2.387929523 -386,Y44H,0.040203334,-0.039072078,0.007924563,-1.334261128,-2.831751718,0.074008604,0.039131736,0.041274931,-0.08105776,-0.066393272,-0.011750884,-0.041518897,0.057368023,-1.064818163,-1.603704093,-2.297848337,-3.365655099,0.795958919,0.75204432,-6.989359248,-5.931827782,-7.976832047,-6.169763466,-7.36584169,-7.502531258,-7.834404477,-3.864455032 -387,Y44K,-0.056311569,-1.557521102,-2.200624853,-2.732368775,-3.16469248,0.061873016,-0.028566048,-0.08405709,-0.179864649,-1.672673845,-1.442368359,-2.2120709,-2.189178805,-2.839221066,-2.625516484,-3.11800873,-3.21137623,0.024296011,-1.115461198,-9.736752542,-9.470126595,-10.69543957,-8.567718597,-10.05385624,-9.896621712,-8.713237983,-6.416687425 -388,Y44M,0.042024964,0.055788355,0.024222335,0.019593148,-0.283943015,0.050952018,0.054180662,0.029869265,-0.055681864,0.030461143,0.081115566,-0.034245929,0.082690599,-0.068737256,0.107923551,-0.222254788,-0.345631242,1.329867247,1.986104669,-4.183576753,-3.574339935,-4.386810173,-4.112641281,-4.366775536,-4.477316841,-3.762886604,0.278472692 -389,Y44L,0.014614007,-0.020088335,-0.004612991,-0.045606461,-0.246511149,0.055245175,0.024009124,0.00521889,0.00594241,-0.047784756,0.007608086,-0.068293069,0.059067087,-0.111328202,0.02011528,-0.211479175,-0.281543123,1.580177299,2.202133025,-4.056317366,-2.658179733,-5.504900871,-3.603613213,-5.549361549,-2.965531464,-3.290529236,2.256448311 -390,Y44N,-0.077406009,-1.325477936,-1.981978275,-2.697710589,-3.041988665,0.136324993,0.019294213,-0.174106231,-0.16184442,-1.312239304,-1.338716567,-2.100278286,-1.863678263,-2.250307196,-3.145113981,-2.830124856,-3.253852473,0.787289898,-0.771315304,-9.665858127,-9.29325222,-10.73499046,-7.657531677,-9.69152581,-10.95199046,-8.720518431,-6.437688822 -391,Y44Q,0.018710097,-0.672057076,-2.272106267,-2.375183941,-3.196583271,0.103022076,0.041143334,-0.00372314,-0.097845943,-0.443399166,-0.900714985,-2.194256567,-2.349955967,-2.520376736,-2.229991145,-3.100194396,-3.292972146,1.004338834,-0.291659593,-10.05262725,-9.848283775,-11.14612659,-8.755823814,-10.58069165,-9.932210426,-8.720518431,-6.437688822 -392,Y44P,0.026203387,-1.250192171,-2.226162408,-2.457348907,-3.027775819,0.070421711,0.050966606,0.001440167,-0.094186604,-1.259382979,-1.241001362,-2.255697903,-2.196626912,-2.451484304,-2.463213509,-2.730271969,-3.325279668,0.578847252,-0.767887358,-10.72467361,-10.64210197,-11.66295556,-9.186104179,-10.39554406,-11.73666228,-8.720518431,-6.437688822 -393,Y44S,-0.041875568,-0.635703169,-2.002437547,-2.317353688,-3.19008419,0.059412067,-0.003955683,-0.079795453,-0.006228569,-0.391702759,-0.879703578,-2.040901808,-1.963973285,-2.058305153,-2.576402223,-2.615846418,-3.764321961,1.123315956,-0.164079843,-8.318059821,-8.327958054,-9.576047096,-5.526725151,-8.026759277,-10.13280952,-6.719616943,-2.506360498 -394,Y44R,0.006585203,-1.275479135,-2.187369786,-2.772341373,-3.025154107,0.057826751,0.035027897,-0.021857492,-0.115109378,-1.236736405,-1.314221865,-2.137616001,-2.23712357,-2.588674907,-2.956007838,-2.809470625,-3.240837589,0.534335731,-0.737128415,-9.548428354,-9.168073212,-11.27351493,-8.795771126,-9.921830948,-8.582951553,-7.990917005,-3.864455032 -395,Y44T,-0.01399395,-0.066186724,-1.320752277,-2.179884405,-3.195373822,0.012717504,0.020645322,-0.048633221,-0.04274268,-0.045031645,-0.087341803,-1.105717908,-1.535786645,-2.13900256,-2.22076625,-2.71882022,-3.671927423,2.147963049,0.7840983,-8.034178278,-7.59798037,-8.88224559,-7.274069183,-8.135916557,-8.280679688,-6.15108948,-2.147847974 -396,Y44W,0.005107688,0.017237439,-0.127504811,-1.605472652,-2.641882621,0.005950779,0.038892894,-0.028677518,-0.019302854,0.013024614,0.021450263,-0.132436891,-0.12257273,-1.376299336,-1.834645967,-2.362657177,-2.921108064,0.978398774,0.744755682,-6.362318027,-5.899110199,-6.682725914,-5.567910034,-5.990093498,-7.671750488,-5.976417446,-1.815319767 -397,Y44V,0.0142365,0.005720869,0.004887949,-0.040962159,-1.726355619,0.010963715,0.038012015,-0.009539015,-0.054385564,-0.013590135,0.025031872,-0.039020878,0.048796776,-0.108545481,0.026621164,-1.536222122,-1.916489116,0.970809488,1.341534885,-2.867259032,-2.735881088,-3.619902786,-3.0599273,-3.667648285,-1.252935699,-2.869941874,3.738011573 -398,I45A,-0.014891277,-0.010251234,-0.003676587,0.060311952,-0.090534046,-0.056741781,-0.034279223,0.004496669,-0.20493012,0.028671473,-0.049173941,0.020743258,-0.028096431,0.119841818,0.000782086,0.013013657,-0.194081748,1.285342084,2.83066336,3.326653287,3.298470413,3.066868988,3.282029709,2.522152779,4.463744545,0.169601665,3.435507963 -399,I45C,0.007388436,0.015949234,0.032874367,0.094765682,-0.208081948,0.074661106,0.02001589,-0.005239018,-0.292511723,0.048737224,-0.016838756,0.053882463,0.01186627,0.128877585,0.060653778,0.017845864,-0.43400976,1.194109223,2.81642152,-1.855377847,-1.227930305,-1.14993161,-0.856829185,-3.564590202,-2.477607933,-2.716622895,0.786985002 -400,I45E,-0.036329991,-0.034148794,-0.020492715,-1.418600532,-2.206823683,0.014938674,-0.049269905,-0.023390076,-0.181041654,-0.029511614,-0.038785974,-0.00329292,-0.03769251,-1.084728433,-1.752472631,-2.273341286,-2.140306079,0.850485667,0.761065561,-2.516617888,-1.766643425,-2.830656815,-1.186383545,-3.521043648,-3.278362007,-3.896640899,-0.896318421 -401,I45D,-0.034741945,-0.217495627,-1.702230135,-2.355596727,-2.744946474,0.018812048,-0.015416655,-0.054067234,-0.1921813,-0.064772051,-0.370219203,-1.343972934,-2.060487336,-2.2500274,-2.461166053,-2.60613134,-2.883761607,0.933372471,0.093055119,-4.010463385,-3.707286316,-4.276267365,-2.925807854,-4.881608093,-4.261347298,-4.839185682,-2.202842813 -402,I45G,-0.020888382,-0.01591693,-0.070622754,-1.601799435,-2.210408061,-0.005257456,-0.024932955,-0.016843809,-0.222332809,-0.016754189,-0.01507967,-0.010982449,-0.130263058,-1.32026252,-1.88333635,-2.212747676,-2.208068446,0.851839074,0.734195582,-2.629017763,-1.068601776,-2.165522102,-1.70922319,-3.516324081,-4.685417664,-3.010405865,0.232191208 -403,I45F,0.036822897,0.051928422,0.050583596,0.120962718,0.139663466,-0.04017073,0.028710773,0.04493502,-0.243426216,0.062187604,0.04166924,0.095602767,0.005564425,0.21213025,0.029795185,0.216195344,0.063131587,0.914274641,3.018596392,-0.14109949,0.109815613,-0.628009018,0.562375031,-1.658426971,0.908747894,-2.129819224,2.489877843 -404,I45H,-0.045660262,-0.011967566,-0.020381376,-0.646046104,-2.169112095,-0.038642684,-0.037582444,-0.053738079,-0.22710956,0.018236766,-0.042171898,-0.005057862,-0.035704889,-0.372596983,-0.919495224,-2.026096634,-2.312127555,1.495026574,1.347648512,-1.219146098,-0.996331963,-1.111905502,-0.589825798,-1.88270372,-1.514963509,-2.31242183,2.063681437 -405,I45K,-0.018968267,-0.399212944,-1.705642668,-2.296539891,-2.947329011,-0.069684191,-0.0415576,0.003621066,-0.189465828,-0.221558154,-0.576867734,-1.606712004,-1.804573332,-2.132555228,-2.460524554,-2.789689164,-3.104968858,1.420247118,0.118345787,-3.883837328,-3.301928169,-5.146250061,-2.907959015,-4.79464463,-3.268404762,-5.259645741,-2.333509679 -406,I45M,-0.004667943,0.018591503,0.007400829,0.06067423,-0.361981496,-0.051515731,-0.00737908,-0.001956806,-0.200949936,0.026662312,0.010520693,-0.022317807,0.037119465,0.10172946,0.019619,-0.179088278,-0.544874714,1.252387475,2.081072839,-0.299366563,-0.213972931,-1.37041983,0.296932594,-1.24780616,1.03843351,-2.962662043,-0.083641429 -407,I45L,0.031797042,-0.005337477,0.021407197,0.073634451,0.108687949,-0.036477322,0.018342041,0.045252042,-0.196976609,-0.000759542,-0.009915411,0.044821819,-0.002007425,0.13535979,0.011909111,0.226670178,-0.00929428,0.945439444,3.111641312,-0.006966663,0.673880844,-0.909884552,1.048926575,0.145036339,-0.992792519,-2.727426884,1.589487343 -408,I45N,-0.012980671,0.018068827,-0.319156277,-1.680797618,-2.632616734,0.054159132,-0.016617431,-0.009343911,-0.254805187,0.047780511,-0.011642858,-0.200784378,-0.437528176,-1.544523359,-1.817071877,-2.50268729,-2.762546177,1.201385217,0.75273817,-3.339684738,-3.254194939,-3.997139877,-2.594777939,-4.193219421,-2.659091515,-4.583091234,-1.935760123 -409,I45Q,0.000276368,-0.018293849,-0.032400378,-0.04257319,-1.581182994,-0.073691823,0.003110448,-0.002557712,-0.17897961,-0.005650598,-0.0309371,-0.012043273,-0.052757483,0.045161589,-0.130307968,-1.50525843,-1.657107558,0.619138335,1.316428965,-1.760384074,-1.334345718,-2.420620621,-1.102562531,-1.914016434,-2.030375069,-3.500349739,-0.649267586 -410,I45P,-0.032289778,-1.48602847,-2.227593906,-2.265296022,-2.896751736,-0.017779745,-0.029995639,-0.034583916,-0.320574314,-1.465157647,-1.506899293,-2.134701358,-2.320486454,-2.227842467,-2.302749576,-2.74364725,-3.049856222,1.792513122,-0.535617481,-4.94666398,-4.272957031,-5.355366127,-4.130775276,-5.78031295,-5.193908516,-6.866717857,-5.589167355 -411,I45S,-0.041614227,-0.01125545,-0.001442758,0.061595782,-1.494600621,-0.011318352,-0.063262464,-0.019965989,-0.22620821,0.033593583,-0.056104482,0.018881702,-0.021767217,0.100276408,0.022915155,-1.364972001,-1.624229241,0.56597735,1.318579774,1.669666541,1.748542648,1.756723038,1.819228676,0.368590004,2.655248337,-1.295651665,2.374909329 -412,I45R,-0.044948252,-0.037685244,-0.240891411,-1.657245813,-2.60881519,-0.003764336,-0.043349719,-0.046546785,-0.233237845,-0.020200821,-0.055169666,-0.101313434,-0.380469387,-1.402827007,-1.911664618,-2.018068781,-3.199561598,2.794793879,1.889843638,-3.019039293,-2.85657653,-3.274664101,-2.265980095,-3.446930634,-3.251045105,-4.260042636,-0.501861679 -413,I45T,-0.041662465,-0.053740798,-0.034064788,0.025185183,-0.426357269,-0.090683898,-0.063211104,-0.020113825,-0.205277131,-0.02276543,-0.084716166,-0.013306181,-0.054823394,0.071564754,-0.021194389,-0.260009143,-0.592705394,0.931599047,1.694327196,1.749060753,1.531735718,1.481282677,1.705367249,0.835747337,3.191170784,-0.817092127,0.967031184 -414,I45W,-0.05570905,-0.088478575,-1.1840278,-2.140760722,-2.910990886,-0.016762281,-0.072527172,-0.038890928,-0.213213255,0.017485675,-0.194442825,-1.046992535,-1.321063065,-1.699441655,-2.582079788,-2.993397688,-2.828584084,2.409469909,1.114131465,-3.205490727,-2.105722733,-4.057880669,-1.318829796,-3.796066299,-4.74895414,-3.230655994,0.430730935 -415,I45V,-0.004989384,-0.04281224,-0.032864558,0.035339036,0.12200949,-0.04214383,-0.020172717,0.010193949,-0.139570265,-0.030712118,-0.054912362,-0.007965682,-0.057763433,0.098874833,-0.028196762,0.190229713,0.053789267,1.543610422,3.106887046,1.784145535,1.918226631,1.30478952,1.898335976,1.39562162,2.403753929,-0.609537134,1.719377433 -416,I45Y,0.031627791,0.011890159,0.058367113,0.10621945,-0.198298791,-0.041183062,0.050049058,0.013206524,-0.257583044,0.021708434,0.002071883,0.052640083,0.064094142,0.144879153,0.067559746,0.015638868,-0.41223645,1.106009441,2.723212628,-0.308281503,-0.699812286,-0.7674776,0.313041862,-1.865627411,1.478467918,-1.454455146,3.358998499 -417,E46A,0.06054994,0.050636307,0.030166752,0.085523852,-0.05797503,0.013691409,0.091959717,0.029140162,0.154220461,0.099576909,0.001695705,-0.017796108,0.078129611,0.0461185,0.124929204,-0.111100066,-0.004849994,1.229407927,2.219399137,-3.808890753,-5.366256149,-3.003720993,-4.174555626,-4.262225418,-2.23769558,-3.642318775,4.487299911 -418,E46C,-0.056629725,0.025298823,-0.009662677,-0.22259505,-1.899140071,0.010692466,-0.030418266,-0.082841184,0.012697907,0.086834869,-0.036237224,0.00360007,-0.022925424,-0.077114147,-0.368075953,-1.845207178,-1.953072964,0.957874186,1.315371901,-8.587476062,-8.806901161,-6.602233582,-10.14982264,-7.989672722,-9.388750206,-5.914546283,0.202951675 -419,E46D,-0.034026852,0.077207259,-0.01121432,0.066829216,-1.243973026,0.070207849,-0.001951889,-0.066101815,0.070873821,0.120517982,0.033896536,0.001117862,-0.023546502,0.084254238,0.049404193,-0.947091228,-1.540854824,0.18103532,1.315883854,-6.28407231,-6.306083374,-5.355953209,-5.749550034,-6.326615189,-7.682159744,-8.707703473,-5.014427893 -420,E46G,-0.0716871,0.022127314,-0.033731841,-0.112749622,-1.769257835,0.047312572,-0.044943791,-0.098430409,0.045381452,0.032843258,0.011411369,-0.015423167,-0.052040515,-0.080134065,-0.145365178,-1.837995065,-1.700520604,0.870913354,1.312266635,-7.88550468,-8.498576492,-6.768200195,-7.905658371,-6.715464317,-9.539624023,-5.151778062,1.027239873 -421,E46F,0.056858218,0.012120929,-0.005820929,0.091624942,-1.180487928,-0.033962325,0.078717836,0.034998599,0.019894801,0.026016262,-0.001774405,-0.034663114,0.023021257,0.066755082,0.116494801,-0.801037275,-1.559938581,0.479584795,1.346875254,-7.66766398,-6.297304291,-6.980595253,-9.270146217,-7.842499023,-7.947775116,-5.086982256,2.794745494 -422,E46I,0.017371427,0.071263735,0.044038186,0.074960336,-0.638274182,0.000588694,0.011841646,0.022901208,0.01318001,0.098159972,0.044367498,0.053893439,0.034182932,0.057686429,0.092234242,-0.555571463,-0.720976901,0.498235184,1.37936072,-4.231761859,-3.472504829,-4.839422783,-3.748002609,-2.647958649,-6.450920425,-2.773764012,3.555232032 -423,E46H,0.016038643,0.038763722,-0.004284774,0.070566517,-0.84199284,-0.010645621,0.064702105,-0.03262482,0.020417451,0.076138904,0.001388539,0.002980277,-0.011549824,0.059088533,0.0820445,-0.619399754,-1.064585926,0.667201688,1.403997961,-9.856631718,-9.940475021,-7.892904518,-11.24007329,-11.11778837,-9.091917397,-7.612027349,-2.585164641 -424,E46K,-0.042628289,0.009826356,-0.028252494,0.05020906,-0.224174499,0.053422087,-0.029650105,-0.055606473,0.004697474,0.086771448,-0.067118736,0.000339186,-0.056844173,0.07971924,0.020698879,-0.182001022,-0.266347976,1.230778489,2.044033568,-7.983046542,-8.664197655,-6.375084496,-8.858606712,-7.35169342,-8.665650429,-8.665464397,-4.892439621 -425,E46M,0.036580697,0.059989659,-0.000607231,0.050199035,-0.019380393,0.00388934,0.035434777,0.037726616,0.063261867,0.13963688,-0.019657562,-0.00344187,0.002227409,0.022660612,0.077737458,-0.01826552,-0.020495266,1.159099384,2.464796203,-5.721038084,-4.642255157,-6.406587486,-6.820715187,-4.474703209,-6.260929382,-3.521903901,1.457089605 -426,E46L,-0.00807517,0.047658725,-0.002553821,0.052847916,-0.114128551,-0.019832737,-0.00376702,-0.01238332,0.057383958,0.088461769,0.006855681,0.001565629,-0.006673271,0.05677958,0.048916251,-0.115979851,-0.112277251,1.243023737,2.18724123,-4.538006567,-3.394428352,-6.556716064,-4.450208595,-3.113876404,-5.174803421,-3.215730677,3.086687004 -427,E46N,-0.009217056,0.05041252,-0.023756553,0.05014026,0.002957374,0.044187716,0.011812087,-0.030246198,0.054513576,0.10628193,-0.00545689,-0.019917459,-0.027595646,0.074618377,0.025662142,-0.048247827,0.054162574,1.231905283,2.494125114,-8.82970883,-8.282891525,-7.528516487,-9.21359021,-8.987594482,-10.13595145,-8.707703473,-5.014427865 -428,E46Q,-0.0000393,0.018893436,-0.052478897,0.040676305,0.013281701,-0.018003293,-0.000370539,0.000291882,0.054529875,0.04139076,-0.003603889,-0.059334277,-0.045623516,0.025962124,0.055390486,-0.021479919,0.04804332,1.200883684,2.47469079,-4.708722372,-4.221145706,-5.062656723,-5.104541771,-3.656731575,-5.498536087,-6.397644746,-1.915014307 -429,E46P,-0.052235465,-1.334710467,-2.157057672,-2.115757725,-2.526018257,0.024315688,-0.030253078,-0.074217852,-0.018536113,-1.321607612,-1.347813321,-2.367930328,-1.946185015,-1.974017808,-2.257497642,-2.445535185,-2.606501329,0.17574834,-0.823624142,-10.38930708,-10.62341103,-9.37322773,-11.79142071,-10.06058698,-10.09788898,-8.513403621,-4.228818024 -430,E46S,-0.019238599,0.000255042,-0.028739924,0.057902964,-0.006555508,0.038353476,-0.01855298,-0.019924218,0.038079569,0.031720898,-0.031210815,-0.025830129,-0.031649718,0.043292607,0.072513321,-0.004788786,-0.008322229,1.153119917,2.483269178,-7.783836906,-8.225326767,-5.116671913,-9.389224083,-7.452924423,-8.735037346,-6.279417779,-0.664948268 -431,E46R,-0.054496014,0.017555477,-0.015553218,-1.238927817,-2.305126814,0.036406638,-0.034105339,-0.074886689,-0.012558232,0.066399326,-0.031288372,-0.017221723,-0.013884713,-0.665080744,-1.81277489,-1.869896154,-2.740357473,1.826191017,1.446219353,-8.536732475,-9.519359489,-7.328752586,-9.701802528,-8.304648407,-7.829099365,-6.68473156,-1.522788132 -432,E46T,-0.03691943,0.018746185,-0.054674958,0.040899157,-0.119318986,0.021289178,-0.031073002,-0.042765858,0.103225619,0.062409485,-0.024917116,-0.022000142,-0.087349774,0.051597051,0.030201262,-0.132083344,-0.106554628,1.437196019,2.35126766,-7.207790399,-8.462076309,-5.750165947,-7.075709122,-6.700850449,-8.050150169,-5.808738174,-0.236334988 -433,E46W,-0.025455624,0.053528052,-0.002827434,-1.371179138,-2.282498331,0.024918929,0.002392595,-0.053303843,0.035329843,0.060204085,0.046852018,0.007712454,-0.013367322,-0.917954226,-1.82440405,-2.159797516,-2.405199146,1.98631072,1.393740757,-9.813522336,-9.799028801,-9.46931176,-11.09954016,-8.457481163,-10.24224979,-6.396960907,-0.549528956 -434,E46V,-0.026138446,0.011802707,-0.021033888,0.047510002,-0.377810222,-0.018590215,-0.018086215,-0.034190676,0.041749152,0.070934786,-0.047329372,-0.021033095,-0.021034681,0.030835808,0.064184196,-0.286296736,-0.469323707,1.359013494,1.959602612,-3.073412158,-3.539405006,-2.898226036,-3.613704819,-2.234872971,-3.080851959,-3.03236904,4.380493027 -435,E46Y,-0.015178575,0.018257015,-0.036370773,0.039721939,-1.06271258,-0.011632763,0.006914764,-0.037271914,0.044365529,0.114175661,-0.077661631,0.001509913,-0.074251459,0.051543201,0.027900676,-0.806396308,-1.319028851,0.603182376,1.366965919,-8.818946312,-8.502829536,-6.69534977,-10.6518856,-8.947990135,-9.296676521,-5.901327855,1.664637617 -436,L47A,-0.051059291,0.003596347,-0.012033631,0.00308627,-0.587413548,0.076982759,-0.074931998,-0.027186583,-0.005942553,0.019082994,-0.011890301,0.009476974,-0.033544235,0.017717286,-0.011544747,-0.386605887,-0.788221209,0.869335544,1.557849448,-5.976561972,-5.868159508,-6.061071358,-6.23526918,-6.835502068,-4.882807747,-4.226155507,-2.330969833 -437,L47C,-0.177895383,-0.010264684,-0.037005878,-0.053354012,-1.720747268,0.054898686,-0.18166569,-0.174125076,0.026060853,0.103521933,-0.1240513,0.049881303,-0.123893058,0.091714584,-0.198422608,-1.332143453,-2.109351082,0.609765311,1.323823782,-6.961350917,-6.905696136,-6.733259422,-6.973345413,-8.270936897,-5.923516716,-5.22799321,-3.692537488 -438,L47E,-0.013553505,0.035271324,0.004499038,-0.390424002,-1.741683954,0.083603992,0.023627269,-0.050734278,0.004727962,0.006651574,0.063891074,0.004701454,0.004296622,-0.068516258,-0.712331746,-1.594751713,-1.888616194,0.804780887,1.324518555,-5.441822897,-6.168141296,-5.322952377,-5.702827164,-7.913175926,-2.102017723,-3.356742602,-1.320094628 -439,L47D,-0.051868795,-0.213851309,-1.447852512,-2.276927975,-2.518467113,0.073470414,-0.064013779,-0.039723811,0.008954258,-0.107920204,-0.319782413,-1.233587675,-1.662117348,-2.469639117,-2.084216833,-2.271598702,-2.765335524,0.974016088,0.117022543,-8.13867099,-8.341438065,-8.463430618,-8.373262749,-8.645823456,-6.869400063,-7.035237185,-3.91987831 -440,L47G,-0.111378734,0.013844164,-0.087146852,-1.661418811,-2.814695063,0.094692222,-0.081204666,-0.141552802,-0.049342564,0.036530436,-0.008842108,0.022069126,-0.196362829,-1.415579768,-1.907257853,-2.484711081,-3.144679044,0.816678433,0.720431104,-6.813700732,-7.064935921,-6.404118187,-7.757251274,-7.125550858,-5.716647423,-5.105666458,-2.971218 -441,L47F,-0.111915134,0.02702744,-0.005378514,-0.034650598,-1.674340022,0.000251126,-0.124618205,-0.099212062,-0.071283237,0.032419184,0.021635695,0.046623987,-0.057381015,0.000498635,-0.069799831,-1.35274265,-1.995937393,0.768567621,1.335126229,-4.025596591,-3.330242172,-3.85523616,-3.148200089,-6.193979256,-3.600325279,-3.280946487,-2.371572923 -442,L47I,-0.00042362,-0.036014443,0.001604926,0.009014886,0.024688881,0.048821878,-0.006509568,0.005662329,-0.014162802,-0.017844302,-0.054184584,0.036526353,-0.033316502,0.064395316,-0.046365545,0.086344472,-0.03696671,1.06323227,2.75959641,-1.987486255,-1.638716301,-2.675816452,-2.777168381,-1.885587334,-0.960142807,-2.952585469,-0.535826644 -443,L47H,-0.042535028,0.003490383,-0.029723903,-1.643207943,-2.394776979,0.03861328,-0.059628997,-0.025441059,0.009260621,0.005599929,0.001380836,0.008416475,-0.067864281,-1.419520492,-1.866895394,-2.476752583,-2.312801374,0.579052138,0.699429082,-4.68906608,-4.306247032,-5.058229225,-5.801630219,-4.84699823,-3.432225693,-3.658150931,-1.851189409 -444,L47K,-0.098578442,0.012938495,-0.033523903,-1.01202238,-2.002716795,0.087138049,-0.064378005,-0.132778878,-0.014665225,0.00739597,0.018481019,-0.032426362,-0.034621444,-0.639665653,-1.384379107,-2.057049191,-1.948384399,1.821381855,1.395874941,-5.093168765,-6.037705551,-4.468633415,-7.533616829,-4.685288727,-2.740599304,-5.102337753,-0.854472629 -445,L47M,-0.030054335,-0.017289793,0.001202834,-0.00286302,0.013633703,0.00604344,-0.035179454,-0.024929216,0.031437411,-0.049824081,0.015244496,0.010151387,-0.00774572,-0.003699317,-0.002026722,0.003215067,0.024052338,1.164682365,2.593359679,-2.866801642,-2.748287895,-3.603169853,-3.127994614,-3.166368416,-1.688187431,-3.247831352,-2.293250483 -446,L47N,-0.106002719,0.050773666,-0.49401955,-1.964018353,-2.469694379,0.082073102,-0.061264769,-0.150740669,-0.056874042,0.03313762,0.068409711,-0.340682615,-0.647356484,-1.622491547,-2.305545158,-2.253754905,-2.685633853,1.638452059,0.856767042,-6.841172453,-7.262988686,-7.265125122,-8.115511696,-5.641012093,-5.92122467,-5.970605431,-3.939739826 -447,L47Q,-0.038064366,0.008879526,-0.022764916,-0.044110424,-0.861640165,0.061419611,-0.071354488,-0.004774243,0.048251261,0.050343976,-0.032584924,0.008605251,-0.054135083,-0.033860879,-0.054359968,-0.535073305,-1.188207025,0.896020182,1.48144071,-4.868536902,-5.512807648,-5.182126038,-5.85766468,-5.084257759,-2.705828384,-3.488338919,-1.956936241 -448,L47P,-0.054203062,-1.385023975,-2.214168575,-2.314785103,-2.838862454,0.08760109,-0.038753876,-0.069652247,-0.104228441,-1.399029979,-1.371017971,-2.069727387,-2.358609762,-2.104133465,-2.525436741,-2.635026278,-3.04269863,-0.016062728,-0.877195519,-9.009735564,-7.181129837,-9.440281128,-10.50915026,-10.43709023,-7.48102636,-6.369178056,-4.931618285 -449,L47S,-0.070025498,-0.007096858,-0.018456814,-0.020467224,-1.746007831,0.069372182,-0.043688386,-0.096362609,0.000648872,-0.000262822,-0.013930894,-0.003107562,-0.033806065,0.041012808,-0.081947256,-1.559387234,-1.932628428,0.637336306,1.315348132,-5.659641037,-5.75806395,-5.736384682,-6.606531242,-5.331501259,-4.865724052,-4.761124145,-2.479968139 -450,L47R,-0.080554719,0.016674459,-0.182974366,-1.659239406,-2.507271637,0.061273978,-0.064869001,-0.096240436,-0.068280453,0.021681214,0.011667704,-0.036211181,-0.329737551,-1.353695421,-1.964783391,-2.103823368,-2.910719905,2.39919235,1.532607764,-3.940149925,-4.592226341,-4.209646461,-4.16333889,-4.377755417,-2.357782516,-3.321682584,-0.513203665 -451,L47T,-0.040328411,-0.001473683,-0.035655428,-0.02291643,-0.895189117,0.039661032,-0.040082386,-0.040574435,-0.007180999,0.00091807,-0.003865435,-0.019970855,-0.051340001,-0.001897201,-0.043935658,-0.597162906,-1.193215327,0.832025127,1.451529502,-4.773603612,-5.008584503,-5.836343948,-5.590960892,-4.046418098,-3.385710617,-3.930647578,-2.043393015 -452,L47W,-0.054333674,0.045842021,-0.033833415,-1.549858724,-2.802612048,0.115609702,-0.016967924,-0.091699424,-0.060595526,0.022970461,0.06871358,-0.000331241,-0.067335589,-1.187807583,-1.911909865,-2.898252187,-2.706971909,0.526928949,0.717310104,-5.462041212,-5.495563622,-5.76848262,-4.908272636,-7.233802811,-3.904084373,-3.665933172,-2.603674053 -453,L47V,-0.039439073,0.017396459,-0.002644581,-0.018979754,0.021797609,0.038118534,-0.061533559,-0.017344586,0.049838699,-0.012132021,0.046924939,-0.015472548,0.010183387,-0.023450808,-0.014508699,0.037644221,0.005950997,1.221993282,2.781093991,-2.602234033,-1.823110016,-3.768652184,-2.462959427,-3.053970856,-1.902477684,-2.582547569,-0.576204739 -454,L47Y,-0.063003098,0.01177264,-0.034851602,-0.020247827,-1.572375898,0.054430947,-0.065430788,-0.060575408,-0.024064245,-0.061443837,0.084989116,-0.057805878,-0.011897325,-0.005874305,-0.034621349,-1.320531299,-1.824220497,0.684650148,1.329924508,-3.977901457,-3.512618256,-4.548266525,-4.123055901,-4.419074287,-3.286492317,-3.753863403,-1.916039961 -455,D48A,-0.021167461,-0.026105558,-0.028627866,-0.062238362,-1.202840841,0.020056556,-0.041043251,-0.00129167,0.004156098,-0.04063843,-0.011572686,-0.041359501,-0.015896231,-0.135480583,0.01100386,-0.887827921,-1.517853761,1.248480294,1.507041257,-5.435668628,-6.135788757,-4.829159439,-3.405207321,-6.794312851,-6.013874771,-4.986498452,-3.173588233 -456,D48C,-0.065482569,0.004249118,0.012368207,-0.138810352,-1.743934184,0.007393545,-0.095325718,-0.03563942,-0.0622893,0.050359372,-0.041861136,0.001639382,0.023097031,-0.103963276,-0.173657428,-1.660553224,-1.827315144,0.790422107,1.317627204,-8.630035666,-10.01272017,-9.23981955,-7.036943436,-9.809575378,-7.051119797,-6.501858519,-4.630611443 -457,D48E,-0.030880974,-0.040698727,-0.051885564,-0.084194609,-0.12991054,0.010224333,-0.053756931,-0.008005017,0.009852059,-0.061937503,-0.01945995,-0.054017199,-0.049753928,-0.118524125,-0.049865092,-0.118060601,-0.141760478,1.450597315,2.265599916,-3.990808118,-4.337031647,-3.863206932,-2.7406567,-5.405126633,-3.608018677,-3.902558976,-2.980442326 -458,D48G,-0.115534799,-0.079927229,-0.081447123,-0.082869369,-1.782656107,0.026251116,-0.122287467,-0.108782131,0.002043347,-0.081035853,-0.078818604,-0.10049717,-0.062397075,-0.092794864,-0.072943874,-1.673329521,-1.891982692,1.080125408,1.340455286,-6.822611116,-7.633766373,-4.67491539,-5.618289093,-9.188933449,-6.997151276,-5.414938788,-3.063343339 -459,D48F,-0.120341789,-0.114151758,-0.270411348,-1.729480531,-2.502426189,0.0109794,-0.151942226,-0.088741351,-0.075662201,-0.030892282,-0.197411234,-0.120230123,-0.420592572,-1.696471908,-1.762489154,-2.419244827,-2.58560755,0.905899002,0.700271235,-10.08087168,-11.81749217,-12.08206539,-8.334009338,-10.76854854,-7.402242966,-7.557286639,-5.774254865 -460,D48I,-0.114177686,-0.051062237,0.010006417,-1.373383494,-2.340419237,-0.045748225,-0.162597926,-0.065757445,0.008418743,-0.015652316,-0.086472157,-0.017302076,0.03731491,-1.132200478,-1.61456651,-2.118214831,-2.562623643,2.2737299,1.506362465,-8.876586653,-11.07857143,-10.74715301,-7.3813964,-9.74418438,-5.431628052,-6.271883715,-5.225569267 -461,D48H,-0.235753333,-0.082682999,-0.144521035,-0.203239903,-1.852532013,-0.036863981,-0.176050569,-0.295456096,0.05318096,-0.031602494,-0.133763504,-0.034567768,-0.254474301,-0.092900669,-0.313579136,-1.440476706,-2.264587319,1.177891237,1.380028023,-5.380125073,-7.854518204,-7.348927414,-2.584703094,-5.460810562,-3.651666092,-4.750180347,-2.360048297 -462,D48K,-0.002479858,-0.045512168,-0.0652093,-1.559207861,-2.633183513,-0.023727654,0.043077291,-0.048037007,0.086251945,-0.040656526,-0.05036781,-0.113117772,-0.017300827,-1.598405318,-1.520010403,-2.446116973,-2.820250053,1.00722918,0.722007831,-8.182988864,-9.002752525,-10.04325862,-5.232564117,-9.26144902,-7.374920036,-6.582040207,-5.29313656 -463,D48M,-0.105161954,-0.121135801,-0.086154034,-0.250932596,-2.264804231,0.011928709,-0.133982868,-0.076341039,-0.006974205,-0.141581565,-0.100690036,-0.073845255,-0.098462813,-0.250153093,-0.251712099,-1.947371908,-2.582236554,1.338899069,1.340119628,-9.6177589,-11.79234985,-10.83293998,-8.024904022,-10.17396596,-7.264634697,-7.256929557,-5.459190575 -464,D48L,-0.05298013,-0.088955561,-0.097753168,-0.866298721,-2.362622239,-0.03812019,-0.058270706,-0.047689554,-0.005580331,-0.069893541,-0.108017581,-0.12215531,-0.073351026,-0.632281026,-1.100316416,-2.098040779,-2.627203699,1.701875386,1.352873286,-8.380416217,-11.16163553,-10.05157662,-6.947889351,-8.95133239,-4.789647194,-6.487669106,-4.052662619 -465,D48N,-0.001229758,-0.087513551,-0.084490151,-0.043579313,-1.278640676,-0.084294937,-0.009649878,0.007190363,-0.013362177,-0.122330143,-0.052696959,-0.122691917,-0.046288384,-0.073270492,-0.013888133,-1.048176965,-1.509104387,0.797038915,1.364972925,-4.140247929,-5.172585243,-5.396025497,-2.844828651,-5.634287163,-1.653513092,-2.739418336,-1.394143348 -466,D48Q,-0.131961078,-0.07314618,-0.105064641,-0.111862622,-1.419343169,0.008091774,-0.202381436,-0.06154072,0.02426692,-0.091545481,-0.054746879,-0.147833796,-0.062295486,-0.16879114,-0.054934103,-1.295522101,-1.543164236,1.304630222,1.429272254,-7.520102141,-8.746371414,-9.428718506,-4.403893005,-8.95201783,-6.069509949,-5.718164588,-4.463772704 -467,D48P,-0.080827336,-0.11438087,-1.269183872,-2.398424719,-3.204843771,-0.004874871,-0.10773466,-0.053920011,0.006210483,-0.055903086,-0.172858653,-1.163202666,-1.375165077,-2.241638598,-2.555210839,-2.788320258,-3.621367283,0.711781696,0.096134008,-9.039518199,-10.47138036,-9.546170471,-6.918922417,-9.631570824,-8.629546928,-6.871316575,-3.734446066 -468,D48S,-0.074913959,-0.096409204,-0.054405515,-0.064171536,-0.813724545,0.024432879,-0.096885276,-0.052942642,0.118417381,-0.04344034,-0.149378068,-0.061143509,-0.047667521,-0.084699665,-0.043643406,-0.613566991,-1.013882099,1.416673241,1.703139408,-5.163692212,-6.830438965,-4.054695892,-3.036894821,-6.587765289,-5.308666092,-4.447010527,-2.971174316 -469,D48R,-0.11589267,-0.0837135,-0.117211746,-1.665141647,-2.492796019,0.035414421,-0.134315481,-0.097469859,0.004127587,-0.057294667,-0.110132332,-0.077130002,-0.15729349,-1.546433271,-1.783850022,-2.322142265,-2.663449773,0.829549719,0.707600079,-6.257029062,-8.264170181,-7.541027779,-2.657672287,-6.89273999,-5.929535072,-5.331222598,-2.759665453 -470,D48T,-0.064041246,-0.108630535,-0.057822122,-0.367886041,-2.654013198,0.010182702,-0.069768317,-0.058314175,0.057592699,-0.090155379,-0.12710569,-0.161425843,0.0457816,-0.315159943,-0.420612138,-2.15048201,-3.157544386,1.702262833,1.358159087,-7.424551889,-9.218329796,-7.720331329,-5.349161728,-8.602973022,-6.23196357,-5.79117872,-4.231739056 -471,D48W,-0.109849701,-0.040945854,-0.457167794,-1.85071631,-2.496025715,0.028060288,-0.116833796,-0.102865605,-0.062554722,0.004283766,-0.086175474,-0.307053594,-0.607281993,-1.806129425,-1.895303195,-2.704993603,-2.287057826,1.397193541,0.743115102,-9.987571748,-11.82792661,-10.29547212,-8.165910286,-10.90272674,-8.745822983,-7.624950393,-5.618271432 -472,D48V,-0.123436205,-0.100342418,-0.076115092,-0.802442827,-2.229344399,-0.029461296,-0.119148332,-0.127724078,0.117227071,-0.071392855,-0.12929198,-0.112590645,-0.039639538,-0.508733714,-1.09615194,-2.227872348,-2.23081645,1.70056127,1.340006709,-7.671322885,-9.954720764,-9.650167519,-6.000151543,-8.642467163,-4.109107437,-6.420206583,-4.057035537 -473,D48Y,-0.120491916,-0.112136982,-0.107335349,-1.531847575,-2.515503785,0.090279484,-0.124141695,-0.116842137,0.030967337,-0.095083228,-0.129190735,-0.12601986,-0.088650837,-1.659857797,-1.403837353,-2.604479465,-2.426528104,1.026334181,0.714551904,-8.815443292,-11.13765137,-10.90940261,-6.745146523,-8.927507111,-6.357508842,-6.611046069,-4.396986032 -474,L49A,0.009349389,0.027332928,0.025682542,0.055011924,-0.398791157,0.133333047,0.079372151,-0.060673373,0.01561417,0.04270075,0.011965105,0.025337053,0.026028031,0.010342192,0.099681656,-0.314749226,-0.482833088,1.070193421,1.722549574,-5.457597258,-3.935032722,-6.591387016,-6.763376381,-5.145233757,-4.852956413,-4.425792864,-2.822849572 -475,L49C,-0.021389187,0.017867822,-0.050937995,-0.072694558,-1.730716884,0.143915038,0.086171289,-0.128949662,0.01049764,0.026932611,0.008803033,-0.00948844,-0.09238755,-0.080019973,-0.065369143,-1.648163994,-1.813269774,0.829410439,1.321010994,-7.196848927,-6.918421295,-7.414606323,-8.045412674,-6.099771652,-7.506032692,-5.765158038,-4.073882429 -476,L49E,-0.050972354,-0.01507065,-0.11613341,-1.629462955,-2.506298315,0.134466741,0.018211701,-0.120156409,-0.101759721,-0.04706364,0.016922341,-0.113107829,-0.119158991,-1.422198118,-1.836727791,-2.266929679,-2.74566695,1.024018931,0.744975886,-8.526647083,-8.00509449,-8.315389046,-9.800883865,-7.740665573,-8.771202438,-6.99453887,-5.329296924 -477,L49D,0.041772056,-0.006964522,-0.801339656,-1.836841629,-2.389768248,0.085948942,0.121567522,-0.03802341,-0.011381275,-0.017441174,0.00351213,-0.63787737,-0.964801942,-1.298282455,-2.375400803,-1.921165266,-2.85837123,3.992482255,2.95605532,-9.545601109,-8.309635139,-9.783354469,-10.31336359,-7.804341591,-11.51731075,-6.722778339,-5.02631127 -478,L49G,-0.064166624,0.008118386,-0.002153457,-0.320083165,-1.948571412,0.124037158,-0.005082992,-0.123250256,-0.016565513,0.029607226,-0.013370454,0.043468153,-0.047775067,-0.154749104,-0.485417225,-1.596316712,-2.300826112,1.142290726,1.356521415,-7.374615791,-5.908962563,-8.398892944,-8.771806847,-6.253803734,-7.539612869,-5.466906267,-4.212212229 -479,L49F,0.02032381,0.032874772,-0.033435021,-0.009401591,-0.12134167,0.039480809,0.101180947,-0.060533327,-0.012496168,0.047206276,0.018543267,-0.00948844,-0.057381601,0.006800084,-0.025603265,-0.130049039,-0.1126343,1.30067394,2.192009275,-4.206474565,-3.889007202,-3.533459351,-5.698352531,-3.880069344,-4.031484398,-5.320025335,-2.76166752 -480,L49I,0.036011655,0.070637907,0.029063234,0.087087169,0.025955322,0.057718676,0.09683095,-0.024807641,0.053431942,0.094190108,0.047085705,0.086334478,-0.02820801,0.128152554,0.046021783,0.034742236,0.017168408,1.123099029,2.88447331,-4.201768993,-4.49939605,-3.979560875,-5.099177238,-3.776219185,-3.654491615,-4.987080959,-1.633741849 -481,L49H,0.037321676,0.040130584,0.016879659,-0.309723234,-1.904127979,0.080282989,0.110478231,-0.035834879,-0.083165663,0.043975351,0.036285817,0.004107976,0.029651342,-0.235894832,-0.383551636,-1.51731899,-2.290936968,1.391661667,1.418493416,-8.119471825,-7.036610275,-7.789581207,-9.343039856,-6.60913475,-9.818993034,-6.379508257,-4.896830591 -482,L49K,-0.023105191,-0.015099101,-0.055811554,-1.172874741,-1.857422077,0.092617117,0.043165542,-0.089375923,-0.035995509,-0.027003846,-0.003194355,0.0075449,-0.119168007,-0.715651016,-1.630098465,-2.078896516,-1.635947637,1.701504418,1.352515193,-6.80907211,-6.085711197,-7.006059845,-8.131258675,-6.679611641,-6.142719193,-5.487785694,-4.780601221 -483,L49M,-0.025127699,0.009347731,-0.032989389,-0.003904621,0.008772386,0.065390268,0.004610341,-0.054865738,-0.036097686,0.052901212,-0.03420575,0.031129411,-0.097108189,0.045372268,-0.053181509,0.010800848,0.006743923,1.144223292,2.691488135,-3.906448198,-3.479596863,-4.386310905,-3.644842995,-4.088151375,-3.933338852,-5.054741694,-3.040362369 -484,L49N,-0.007183727,0.017364313,-0.054132898,-0.371503744,-1.928298964,0.107140613,0.053262029,-0.067629483,-0.103100289,0.010271114,0.024457512,-0.079657665,-0.02860813,-0.200279327,-0.54272816,-1.770774069,-2.085823858,1.2418821,1.349998314,-8.368614497,-7.795747177,-7.38650573,-9.930825783,-7.014296379,-9.715697418,-6.592324491,-4.151768701 -485,L49Q,-0.122437675,-0.024370565,-0.067796907,-0.090924698,-1.759798399,0.172771444,-0.065991565,-0.178883785,-0.045454654,0.026513728,-0.075254857,-0.035295703,-0.10029811,0.025722837,-0.207572233,-1.929598434,-1.589998363,0.590648405,1.296740411,-6.637604391,-5.722825623,-6.389389397,-7.717575294,-5.719410828,-7.638820816,-5.175834604,-4.468953361 -486,L49P,-0.028853608,0.024618252,-0.004727614,-0.244371135,-1.963572886,0.108744719,0.057783565,-0.11549078,-0.089990344,0.023801475,0.025435029,0.011027929,-0.020483156,-0.121030383,-0.367711886,-1.80662293,-2.120522842,0.978372394,1.320525046,-4.882713327,-4.383366791,-5.300119514,-5.742442116,-4.44438121,-4.543257004,-4.016912262,-2.350246851 -487,L49S,-0.027019788,-0.012416005,-0.022086376,0.002435373,-1.676670922,0.11216828,0.057931305,-0.111970881,-0.00752886,0.010928307,-0.035760317,0.008531186,-0.052703937,0.018574518,-0.013703772,-1.344999869,-2.008341975,0.78865909,1.338309624,-5.546601926,-4.828681824,-5.266731285,-6.797354912,-4.885446953,-5.954794655,-4.195069406,-2.669018597 -488,L49R,-0.007669468,0.006198338,-0.036104698,-1.39980136,-2.058053405,0.092936331,0.038281703,-0.053620638,-0.080341118,-0.011225215,0.02362189,0.001707034,-0.073916429,-1.083368443,-1.716234277,-1.490933372,-2.625173437,3.555143042,2.880704209,-7.196218359,-4.844845825,-7.79799662,-8.165689331,-6.389884468,-8.782675552,-5.561558235,-4.512566393 -489,L49T,0.027307709,0.020935829,-0.007092364,0.003132137,-0.566029879,0.075163415,0.088277447,-0.033662029,-0.020952672,-0.030656021,0.072527679,0.000611887,-0.014796615,0.007044482,-0.000780208,-0.461156321,-0.670903437,0.756821849,1.468778458,-4.128080345,-3.117119972,-4.889680756,-4.994410072,-3.749801727,-3.889389198,-3.119054137,-0.258416625 -490,L49W,0.051489205,-0.007868046,0.018648244,0.01802376,-0.076008527,0.054655533,0.095169254,0.007809156,0.005888109,0.021086182,-0.036822273,0.030752779,0.006543709,0.024839426,0.011208093,-0.016414935,-0.135602119,1.484867843,2.833193077,-9.161803276,-8.75562529,-8.953390945,-9.456890747,-8.146909698,-10.4961997,-8.343969717,-7.057598991 -491,L49V,0.019838762,0.038435602,0.034548711,-0.006204268,-0.043917615,0.073670734,0.098679154,-0.05900163,-0.034816585,0.054191768,0.022679436,0.111489675,-0.042392253,0.067925219,-0.080333755,-0.005456367,-0.082378863,1.227003906,2.729191112,-3.729945303,-3.74064769,-3.929360344,-4.586241798,-3.98576049,-2.407716194,-3.506266077,-1.737977918 -492,L49Y,0.004036225,0.016423706,0.005364348,-0.004842151,-0.105296504,0.104310184,0.05043952,-0.042367071,0.005522336,0.023349396,0.009498015,0.016593362,-0.005864666,0.025067903,-0.034752204,-0.083152443,-0.127440564,1.307360183,2.342055252,-6.931931645,-6.597687149,-6.528364868,-8.117919441,-5.417604927,-7.998081841,-6.246694482,-3.938290216 -493,N50A,-0.008084997,-0.010696856,-0.036183766,-0.002009195,-0.032218326,-0.001880045,-0.012713661,-0.003456332,0.045044948,-0.026481224,0.005087513,-0.009799657,-0.062567874,-0.003001677,-0.001016713,-0.030726706,-0.033709946,1.297699302,2.592330939,2.225923572,1.829734818,2.450700096,3.032368713,2.353590324,1.463223907,0.400537436,1.050228126 -494,N50C,-0.019290946,-0.029554896,-0.013085317,0.027809537,-1.223080702,0.094070154,0.015158235,-0.053740127,0.004290877,-0.017488304,-0.041621488,0.020282463,-0.046453097,-0.003367603,0.058986677,-0.851844498,-1.594316905,0.406638,1.336012309,-3.64956243,-3.760769081,-3.199836121,-2.476058411,-3.950444611,-4.860703926,-5.243266292,-4.296661206 -495,N50E,-0.010813871,-0.023545543,-0.060759267,-0.006930653,-0.017852372,-0.032640196,-0.033614369,0.011986628,0.066806717,-0.029349772,-0.017741314,-0.039526473,-0.08199206,-0.034967358,0.021106053,-0.020463977,-0.015240766,1.274597881,2.547224212,-0.01725918,0.191334946,0.371022591,0.774214348,-0.838738647,-0.584129135,-1.639093228,0.768753036 -496,N50D,-0.000362991,-0.001021611,-0.000616795,0.031498602,-0.01891356,-0.056921607,-0.028705488,0.027979506,-0.01299482,0.014256395,-0.016299617,0.013993381,-0.01522697,-0.006421268,0.069418471,-0.012425397,-0.025401723,1.296986275,2.686218378,-0.216246426,-0.489789825,-0.296828812,-0.176204269,-0.037966698,-0.080442528,-2.757522432,1.189025998 -497,N50G,0.010918123,-0.011505466,-0.012991626,0.013356464,-0.018879235,-0.019337947,0.002186642,0.019649603,0.027401514,-0.026275782,0.00326485,-0.013422628,-0.012560624,-0.018677283,0.045390211,-0.042923503,0.005165033,1.463645502,2.58767748,0.254996309,0.581983315,0.148864204,0.684148949,0.859072426,-0.999087349,-0.856568856,1.460456013 -498,N50F,-0.000322013,-0.039831523,-0.004645147,-0.014366639,-0.082938465,0.002889796,-0.004918116,0.00427409,0.047196745,-0.041833332,-0.037829714,-0.006184821,-0.003105473,-0.017278688,-0.01145459,-0.091616967,-0.074259963,1.230673727,2.206676778,-3.587364079,-3.609142075,-3.174598228,-2.542659355,-4.07961438,-4.530806358,-5.335282447,-3.625255995 -499,N50I,-0.007572027,-0.053279155,0.00296178,0.040509753,-0.050837261,-0.015527809,-0.036051868,0.020907815,-0.015567777,-0.071961083,-0.034597226,-0.003825773,0.009749333,-0.01649428,0.097513786,-0.056491434,-0.045183088,1.315948249,2.403880648,-1.970203613,-1.706909698,-1.450253075,-0.975685478,-2.3660439,-3.352125916,-4.658404872,-2.249634551 -500,N50H,0.02568454,-0.007074709,-0.002432786,0.057300434,0.010744474,-0.027480612,0.004180202,0.047188878,-0.060775539,-0.020669504,0.006520087,0.000924055,-0.005789627,0.031719916,0.082880951,0.001127745,0.020361203,1.170341736,2.572464589,-0.970511105,-0.013208984,-1.108956573,-0.457947472,-1.724150093,-1.548292404,-2.619911038,-1.105208958 -501,N50K,0.038498322,0.030005389,0.036899416,0.020504778,-0.000322556,-0.011371362,0.043571271,0.033425372,-0.035305858,0.002399823,0.057610955,0.056866925,0.016931906,-0.00741841,0.048427966,0.00143379,-0.002078901,1.177895262,2.6053618,0.165758078,0.71181105,0.634507935,0.613671707,-0.838377167,-0.292823135,-2.729375489,0.153071996 -502,N50M,0.025102831,0.08440997,0.070633363,0.061432125,0.051670551,-0.033725571,0.026342955,0.023862707,-0.014325854,0.087391532,0.081428407,0.073637135,0.06762959,0.077752052,0.045112198,0.048596027,0.054745074,1.112279219,2.632444793,-2.726359142,-2.921453804,-1.913366333,-1.986578133,-3.002580048,-3.80781739,-4.956621297,-3.497183149 -503,N50L,0.004176773,-0.003928236,0.002793244,0.035434023,-0.025187338,0.011849507,-0.000929413,0.009282959,0.018310207,-0.005951342,-0.001905129,-0.000528841,0.006115328,-0.013932711,0.084800756,-0.026614968,-0.023759707,1.4150289,2.619920111,-1.746993504,-1.770884201,-1.007593002,-0.790260612,-1.885758064,-3.280471642,-3.560377453,-2.722058087 -504,N50Q,-0.034149908,-0.025746897,-0.005560274,-0.004803838,-0.030864239,-0.026081816,-0.070732568,0.002432752,-0.080925792,-0.040319285,-0.011174509,0.001889087,-0.013009635,-0.047476969,0.037869293,-0.002095514,-0.059632964,1.238762276,2.562574386,0.180163776,0.761212715,0.252830681,0.672454567,-0.659473778,-0.126205307,-2.391201077,-0.191000374 -505,N50P,-0.023845295,-0.023818331,-0.04224872,-0.004277632,-0.037237915,0.019940609,-0.027595201,-0.020095389,-0.05125764,-0.028868498,-0.018768164,-0.033057906,-0.051439534,-0.039822982,0.031267718,-0.031779322,-0.042696507,1.34675048,2.55281712,-1.500244243,-1.650393158,-1.89874144,-1.011499504,-0.812555473,-2.128031639,-4.168961106,-1.479827949 -506,N50S,0.005311758,0.008731341,0.002270534,0.035178948,-0.013873543,-0.003521224,0.005232586,0.00539093,0.018288786,-0.006976869,0.02443955,0.030300538,-0.025759471,0.022035366,0.048322529,-0.004379002,-0.023368084,1.211511191,2.571277778,0.558419965,0.226065842,0.882407875,1.171736046,0.497601563,0.014288498,-1.870124426,-0.053767358 -507,N50R,-0.023695211,-0.023526739,-0.020184106,0.018598537,-0.036412893,-0.017556824,-0.031681549,-0.015708873,-0.02769758,-0.021082536,-0.025970941,0.005270632,-0.045638844,0.006145339,0.031051734,-0.011810751,-0.061015035,1.308162411,2.665652859,-0.215722052,0.604579834,0.275983498,0.726639816,-1.117773582,-1.568039825,-2.464228779,-0.042224125 -508,N50T,-0.014458039,0.015155161,0.003281957,0.006063689,-0.008385861,-0.004020308,-0.034910674,0.005994597,-0.012008907,0.006723221,0.023587101,0.017023227,-0.010459313,-0.010463799,0.022591176,-0.005723173,-0.011048549,1.215730156,2.850969187,0.781448181,0.423739418,1.498049065,1.437992622,0.85495237,-0.307492569,-1.138271929,-0.190745853 -509,N50W,-0.001582908,0.008164795,0.013075457,0.011461234,-0.021802643,0.014398281,-0.008749722,0.005583906,-0.042639056,-0.006706111,0.0230357,-0.008355088,0.034506001,0.015032656,0.007889812,-0.046507617,0.002902331,1.1321617,2.338242551,-4.470520325,-3.93557135,-4.341664749,-3.633132561,-4.841911774,-5.60032119,-5.976090783,-4.091725199 -510,N50V,0.004001322,-0.020066022,-0.030175905,0.0158949,-0.016311532,-0.024784184,-0.013346487,0.02134913,-0.001813341,-0.041030499,0.000898456,-0.030887137,-0.029464673,-0.0154227,0.0472125,-0.035472318,0.002849254,1.194165551,2.437284771,-0.188532553,0.055017342,0.674477478,0.907910591,-1.039512703,-1.540555473,-2.490702828,-1.178196581 -511,N50Y,0.008904689,-0.01490496,-0.007164311,0.005260869,-0.041849916,-0.009206242,-0.00633791,0.024147288,-0.045178639,-0.028905446,-0.000904474,-0.060033695,0.045705073,-0.024686081,0.035207819,-0.062449657,-0.021250174,1.258514628,2.348652214,-3.372337065,-2.638630791,-3.194357246,-2.819585014,-3.834533493,-4.374578781,-5.096726983,-3.113312008 -512,S51A,-0.003110825,0.003951099,-0.002442861,0.00882037,-0.739318788,0.024115963,0.002104804,-0.008326454,-0.013147999,0.003682094,0.004220104,-0.021728466,0.016842745,-0.013778042,0.031418781,-0.505529847,-0.973107729,1.151533062,1.621697353,-3.027872137,-2.941236496,-2.868091484,-3.423185524,-2.181104836,-3.725742348,-5.461872252,-2.343243786 -513,S51C,-0.044688877,0.04816891,-0.032840674,-0.780664559,-1.818743993,0.104584094,-0.015782624,-0.07359513,-0.102106469,0.096158638,0.000179181,-0.058497062,-0.007184286,-0.468763857,-1.092565261,-1.684035536,-1.95345245,1.756262933,1.484305296,-7.252824742,-7.147603569,-7.074056938,-7.545273918,-7.076808739,-7.420380547,-8.046940046,-4.016271463 -514,S51E,-0.024542575,0.008071454,0.012977032,-0.004208255,-0.086824363,0.03604074,-0.045042871,-0.004042279,0.008550784,-0.025929064,0.042071972,0.010381706,0.015572358,0.020291975,-0.028708485,-0.072529769,-0.101118956,1.311983428,2.384162345,-3.871490565,-3.833378555,-3.365032478,-4.282151802,-2.713734848,-5.163155144,-5.919291851,-2.228324842 -515,S51D,0.010510866,0.053458564,0.052309327,0.086368427,0.075247281,0.044138814,0.003131794,0.017889938,-0.096845128,0.020697981,0.086219147,0.044549621,0.060069032,0.106540203,0.066196651,0.074847804,0.075646758,1.12715838,2.926982089,-2.454435864,-2.94208355,-2.070842567,-2.443288925,-1.519681465,-3.296282814,-4.078479491,-0.965591405 -516,S51G,-0.011771686,-0.025383054,-0.042533506,-0.004001896,-0.369043249,0.019691329,0.017543543,-0.041086914,-0.097993924,-0.061654884,0.010888777,-0.067776709,-0.017290303,-0.061332715,0.053328923,-0.297714451,-0.440372046,1.287357844,1.840626853,-2.611165483,-2.611798157,-2.0271894,-3.066989006,-1.471996712,-3.877854141,-4.407296703,-0.915042685 -517,S51F,-0.035170724,0.105737282,0.033076164,-0.042512381,-1.75070567,0.080784026,0.017316009,-0.087657457,-0.109479009,0.117052398,0.094422165,0.094471129,-0.028318801,-0.114003916,0.028979155,-1.732014487,-1.769396852,0.839714032,1.315902222,-7.835615195,-7.277496925,-8.014218796,-7.443705856,-8.838178597,-7.6044758,-7.534595329,-3.935402216 -518,S51I,-0.037858996,0.010978864,-0.086036201,-0.12256795,-1.335857706,0.03767522,0.000822506,-0.076540498,-0.083073513,0.006331635,0.015626092,-0.055225953,-0.116846449,-0.021163636,-0.223972263,-1.311914688,-1.359800723,0.806239679,1.343504933,-8.267238388,-7.683211151,-9.09937365,-8.837461647,-8.609893585,-7.106251907,-8.590728581,-5.655949529 -519,S51H,-0.054228684,0.005484843,-0.064991767,-0.032996085,-0.605656207,-0.033705065,-0.049184278,-0.059273089,-0.097146141,0.038050709,-0.027081023,-0.030288051,-0.099695483,-0.058124566,-0.007867604,-0.420293626,-0.791018787,1.428583659,1.865563966,-6.307050037,-6.362521996,-6.069293854,-5.781919014,-5.992786331,-7.328728989,-7.237775376,-4.132124773 -520,S51K,-0.006533424,0.005048771,-0.093152136,-0.080652788,-0.668958334,0.07220687,0.048637355,-0.061704203,-0.119065481,-0.016599262,0.026696804,-0.13731219,-0.048992081,-0.094053689,-0.067251886,-0.446707276,-0.891209391,1.449739916,1.841853729,-4.354200017,-4.316860825,-4.09650045,-4.531218788,-3.872161537,-4.954258484,-6.352390757,-2.704196405 -521,S51M,-0.00846214,0.03231386,0.02757966,-0.011123829,-1.386030888,-0.007682441,-0.025330468,0.008406188,-0.081490858,0.011582936,0.053044783,0.001538872,0.053620447,0.002445255,-0.024692912,-1.148562968,-1.623498808,0.705857139,1.344347789,-7.432698781,-6.830210938,-7.346100975,-8.393603012,-7.840288414,-6.753290565,-7.830402536,-5.191827577 -522,S51L,-0.002279193,0.021024867,-0.003305348,-0.008331066,-1.461622603,0.067083038,0.030187878,-0.034746264,-0.11909463,0.000102935,0.041946798,-0.027660432,0.021049737,-0.036061742,0.01939961,-1.373298063,-1.549947142,0.818098972,1.338460985,-7.41173073,-6.863543877,-7.307715195,-8.22782988,-8.244294449,-6.415270248,-7.437962989,-4.726175625 -523,S51N,0.012952954,0.044632218,0.025758462,0.037980149,0.017691821,-0.009411787,0.000466381,0.025439527,-0.081189369,0.009704242,0.079560193,-0.018141268,0.069658192,0.00282491,0.073135387,0.004096124,0.031287517,1.143532076,2.702124819,-2.258556158,-2.811522507,-2.279665062,-2.381668938,-1.338768349,-2.481155937,-3.898803444,-1.192555578 -524,S51Q,-0.014713446,-0.034990407,-0.019036116,-0.023834079,-0.454083284,0.009577845,0.006072407,-0.035499298,-0.095895819,-0.065663737,-0.004317077,-0.012125125,-0.025947107,-0.018350611,-0.029317546,-0.271114101,-0.637052467,1.385069754,2.021961315,-5.034011494,-5.058857224,-4.77027462,-4.957090347,-4.216345703,-6.167489578,-6.145465445,-3.237922399 -525,S51P,-0.062556613,-0.007302388,-0.276801636,-1.687142933,-2.620159281,0.086343981,-0.03463264,-0.090480586,-0.102501425,-0.006680587,-0.007924189,-0.226428925,-0.327174346,-1.618133717,-1.756152148,-2.56153363,-2.678784932,1.292604661,0.756880075,-6.937806532,-5.962718079,-6.621341568,-6.86277375,-7.021867477,-8.220331787,-7.251630502,-3.585030683 -526,S51R,-0.02499057,0.002845319,-0.014492931,-0.01861232,-1.166772263,0.055392326,0.016255882,-0.066237022,-0.048319258,0.027761782,-0.022071145,-0.020645703,-0.008340158,-0.040765707,0.003541067,-0.83249896,-1.501045565,0.925942028,1.421243932,-3.997860786,-3.783240921,-4.080841171,-3.521299461,-3.37298732,-5.230935059,-5.785746712,-2.413292354 -527,S51T,-0.029466071,-0.02768787,-0.010498036,0.002427636,0.006249997,0.006875507,-0.02033942,-0.038592721,-0.020247936,-0.021796997,-0.033578743,-0.002413765,-0.018582306,-0.013253449,0.01810872,0.005396449,0.007103544,1.312553584,2.661026548,-0.903647209,-0.819322464,-0.824447632,-1.401025665,-1.502978355,0.029538071,-3.137374733,0.478257077 -528,S51W,0.001588234,0.003864143,-0.000930465,-1.257708532,-2.260674765,0.099042763,0.025701697,-0.022525229,-0.097666566,-0.026890098,0.034618383,-0.019694977,0.017834048,-1.069810325,-1.445606739,-1.749968803,-2.771380726,2.825242121,2.091728656,-8.809051311,-8.198051941,-8.730688751,-9.177346962,-8.570997597,-9.368171303,-8.73605875,-6.163029839 -529,S51V,0.044296828,0.035245693,0.023986122,0.024310054,-1.719458446,0.070797273,0.093772269,-0.005178614,-0.114106867,0.014602406,0.05588898,-0.018460084,0.066432328,-0.010619651,0.059239759,-1.451761355,-1.987155536,0.713452036,1.322025329,-7.48566114,-7.014602699,-7.7567631,-8.047302361,-7.371370811,-7.238266731,-7.909634371,-4.879930185 -530,S51Y,-0.0021061,-0.001298404,0.006027365,0.014509847,-1.419267838,0.021413274,0.005692476,-0.009904675,-0.169446028,-0.005156428,0.00255962,0.009832789,0.002221941,0.012159049,0.016860644,-1.322282954,-1.516252721,0.811011548,1.340853164,-8.981587416,-8.56538324,-9.443399208,-8.187927803,-9.384058197,-9.327168633,-8.31440531,-5.624510435 -531,G52A,-0.047540555,-0.026315206,-0.001094208,0.004574982,-1.397547239,-0.020527633,-0.0776331,-0.017448009,0.042918953,0.024074044,-0.076704455,0.036529686,-0.038718102,0.03971082,-0.030560856,-0.941951731,-1.853142747,0.705429432,1.362729995,-4.268182642,-4.54104258,-2.812916542,-3.755971764,-4.200309708,-6.030672615,-3.850479131,-3.44375813 -532,G52C,-0.050390136,0.011548613,-0.506589603,-1.390731118,-2.765819379,0.100262251,-0.05765877,-0.043121501,-0.039428825,0.055839367,-0.032742142,-0.274332415,-0.738846791,-1.344251292,-1.437210944,-2.422823856,-3.108814902,1.551748794,0.893002159,-8.177728903,-7.754408089,-7.589241081,-7.454473335,-8.278901199,-9.811620811,-7.651098412,-7.248742476 -533,G52E,-0.052895474,-0.011349755,-0.02519872,-0.017728775,-1.485419039,-0.032505388,-0.05358206,-0.052208888,-0.095418816,0.038979189,-0.061678698,0.025661311,-0.07605875,-0.02301791,-0.012439639,-1.274221201,-1.696616877,0.637829016,1.329612933,-3.857984549,-4.01368042,-2.714966103,-4.00724408,-4.125222305,-4.428809837,-4.399830894,-3.096078355 -534,G52D,-0.025476422,-0.028010881,0.037914649,-0.02815374,-1.142466432,0.002442821,-0.04527852,-0.005674324,0.042917138,-0.013377638,-0.042644123,0.049065029,0.026764269,-0.010629476,-0.045678003,-0.962918321,-1.322014543,0.523897175,1.339254332,-3.233483171,-3.293809402,-1.927869896,-2.814379814,-3.926978958,-4.204377785,-2.827768827,-2.447173425 -535,G52F,-0.07096396,-0.013820836,-0.018118286,-0.247686319,-2.243396686,-0.016991139,-0.070077948,-0.071849971,-0.022227934,-0.017791971,-0.0098497,-0.004414366,-0.031822205,-0.202114679,-0.293257958,-1.588556664,-2.898236707,1.261669133,1.376618698,-8.377659857,-7.553649498,-7.743204414,-7.701173645,-7.895915733,-10.994356,-7.578358091,-6.636905811 -536,G52I,-0.065158743,-0.087096005,-0.355802644,-1.850621565,-3.029309641,0.048424759,-0.080932764,-0.049384721,0.02651815,-0.044143497,-0.130048513,-0.304647627,-0.406957661,-1.693744671,-2.007498458,-2.580431709,-3.478187573,1.405429449,0.767937278,-8.342276598,-7.669541946,-7.594753548,-7.287010918,-8.523553291,-10.63652328,-7.820823138,-6.99200141 -537,G52H,-0.075044202,-0.079751039,-0.03525133,-0.035948583,-1.650707599,-0.035912141,-0.091571937,-0.058516466,0.064000705,-0.001321571,-0.158180507,-0.0000807,-0.07042196,-0.003787101,-0.068110064,-1.436016869,-1.865398328,0.705833254,1.325144169,-5.376852747,-4.926141823,-5.245388657,-5.305131668,-5.53918927,-5.868412315,-5.245564759,-4.166941142 -538,G52K,0.003140753,-0.059740261,-0.010615719,-0.121282596,-1.679006303,-0.002956593,-0.014326261,0.020607767,0.065659698,-0.050033377,-0.069447145,-0.032402119,0.011170682,-0.104205139,-0.138360052,-1.814800918,-1.543211688,1.030317726,1.323075299,-4.312924689,-3.993909683,-4.020330437,-4.442755562,-4.472876312,-4.63475145,-4.341970479,-2.686857259 -539,G52M,-0.058545358,-0.022569127,-0.019596767,-0.08402447,-1.645114846,-0.0298781,-0.082441869,-0.034648847,0.016701069,0.007510878,-0.052649132,0.002371624,-0.041565158,-0.080271426,-0.087777513,-1.601920625,-1.688309066,0.857702322,1.326226282,-8.261242461,-7.393528656,-7.481476265,-7.034510704,-8.138826836,-11.25786984,-7.198189641,-6.636905609 -540,G52L,-0.012440137,-0.019598826,0.007416516,-0.23253181,-1.737240536,-0.012168779,-0.023668024,-0.00121225,-0.008176188,-0.014041591,-0.02515606,-0.006998167,0.021831198,-0.156140096,-0.308923523,-1.72786136,-1.746619712,1.083384718,1.335722885,-6.835377272,-5.998673912,-6.164090988,-5.914792793,-7.151677841,-8.947650826,-6.12304038,-5.109115458 -541,G52N,-0.016179965,-0.015956314,-0.001694975,-0.040297307,-0.564540738,-0.066773254,-0.050902375,0.018542446,0.158885754,0.051521137,-0.083433764,0.028827853,-0.032217802,-0.036406108,-0.044188506,-0.496150742,-0.632930734,0.762351987,1.462077457,-2.994063556,-3.450037231,-2.818676483,-3.051779533,-3.559275009,-2.090549522,-3.263201706,-2.151628657 -542,G52Q,-0.043054485,0.027510531,-0.004828025,0.016663182,-1.581973632,-0.038198188,-0.047786604,-0.038322366,0.048540576,0.051342848,0.003678214,0.010680771,-0.02033682,0.049031903,-0.015705539,-1.397277835,-1.766669429,0.616904972,1.320265214,-4.290208435,-3.903479218,-3.961047569,-4.058373238,-4.404859032,-5.123283119,-4.257980327,-3.272199401 -543,G52P,-0.031945269,-0.018313373,0.01099754,-1.06203159,-1.923346365,-0.000876739,-0.057458813,-0.006431724,-0.000892616,-0.001431701,-0.035195045,0.030398474,-0.008403394,-0.703383709,-1.420679471,-1.909061072,-1.937631658,1.928080616,1.469151095,-5.095099393,-5.17498925,-3.360198647,-5.118368515,-5.863037376,-5.958903175,-4.855248352,-3.515278934 -544,G52S,-0.010350649,-0.019063312,-0.009109004,0.020904795,-1.555244441,-0.049930759,-0.035894959,0.015193661,-0.025542684,0.004021938,-0.042148561,0.005262781,-0.023480788,0.0366098,0.00519979,-1.484761705,-1.625727177,0.76574886,1.328631204,-3.917324789,-4.013838951,-3.549087105,-3.5842398,-4.237189438,-4.202268654,-3.915683562,-3.276713795 -545,G52R,-0.0123626,0.021081446,0.014971346,-0.381886376,-2.042379701,-0.01646359,-0.025800267,0.001075068,-0.020902981,0.057772347,-0.015609455,0.00910685,0.020835841,-0.205480352,-0.5582924,-1.667269668,-2.417489733,1.260084795,1.364649007,-4.735410483,-4.36916066,-4.402980827,-4.039680534,-5.053335434,-5.811894959,-4.347794545,-2.95190814 -546,G52T,-0.028814535,-0.014915852,-0.011225543,-0.149252886,-1.727659998,-0.00919026,-0.065441242,0.007812173,0.009218692,0.010990569,-0.040822273,-0.024792258,0.002341173,-0.063936415,-0.234569357,-1.599645636,-1.855674359,0.780078833,1.3204224,-5.191263089,-4.556334015,-4.239205193,-4.469777046,-5.071033997,-7.619965195,-4.898574967,-3.709303017 -547,G52W,-0.042030153,-0.024696265,0.002043834,-0.623120863,-1.984352478,0.036422099,-0.035813558,-0.048246748,-0.019851474,-0.049908274,0.000515744,-0.01428512,0.018372787,-0.456534073,-0.789707652,-1.790909093,-2.177795862,1.662455749,1.427692661,-8.232757307,-7.30501619,-7.8956138,-7.885926544,-8.177372948,-9.899857056,-7.095832497,-6.474529788 -548,G52V,-0.02586983,-0.010626934,0.028371198,-1.416511474,-2.323342864,-0.002087798,-0.038720869,-0.013018791,-0.0000426,0.014627688,-0.035881556,-0.019867877,0.076610272,-1.290748217,-1.542274731,-1.989109539,-2.657576189,2.623708565,1.779119592,-7.390353557,-6.924515152,-6.261839012,-6.462740662,-7.175654076,-10.12701888,-6.929398357,-5.708914425 -549,G52Y,-0.108321779,-0.060638248,-0.000931884,-0.380029321,-2.109773078,-0.003303283,-0.125178942,-0.091464615,-0.050877544,0.020117239,-0.141393734,0.049043081,-0.050906848,-0.186023989,-0.574034652,-1.486941356,-2.7326048,1.246786733,1.389292094,-8.075219528,-6.914054939,-8.008847435,-7.948563652,-7.730641968,-9.773989647,-7.288614875,-6.389109022 -550,K53A,-0.009480222,0.001371396,0.009175101,0.020797248,-0.009332043,-0.012781208,-0.004421919,-0.014538525,-0.010372865,0.023404774,-0.020661982,0.029755544,-0.011405343,0.011598056,0.02999644,0.022921597,-0.041585683,1.120589182,2.633820608,-1.677988852,-1.765996468,-1.013070175,-1.538630867,-2.558896904,-1.513349846,-2.764899118,0.296810672 -551,K53C,-0.054359667,0.01147139,-0.030007354,0.025694929,-1.382777082,0.07859433,-0.052589045,-0.056130289,0.103453299,0.028625262,-0.005682483,0.019109233,-0.07912394,0.023166858,0.028222999,-1.08560626,-1.679947904,1.008104357,1.397465929,-6.848581253,-6.000081024,-6.299377419,-7.334269577,-7.567601883,-7.041576363,-7.346845242,-5.379504032 -552,K53E,-0.057326985,-0.022193405,-0.038447907,-0.038052717,-0.017441509,-0.0064613,-0.072598768,-0.042055201,-0.014469506,-0.033112007,-0.011274802,-0.041761365,-0.035134448,-0.045652713,-0.03045272,-0.006527652,-0.028355365,1.065666366,2.623297486,-2.0756151,-1.912175842,-1.480044083,-3.154644844,-2.446250992,-1.38495974,-2.864317392,0.627909394 -553,K53D,-0.007795902,0.001605078,0.035474456,0.041011577,0.013371071,-0.018466342,-0.007797217,-0.007794587,0.005293256,0.033207337,-0.029997181,0.023242208,0.047706704,0.019959189,0.062063965,0.036301313,-0.009559172,1.259491033,2.893017684,-3.671956697,-2.468883987,-2.649551987,-5.173734314,-4.975590034,-3.092023163,-4.119900862,-0.024595094 -554,K53G,-0.041356335,0.01232886,0.02294722,0.032055247,-0.093902637,0.026207282,-0.03984317,-0.042869499,0.034754131,0.050752206,-0.026094486,0.056006943,-0.010112503,0.064342016,-0.000231522,-0.030476666,-0.157328608,1.237023233,2.517427644,-4.675491692,-3.639215332,-3.94985183,-6.313111641,-5.794354706,-3.68092495,-4.650691053,-0.997732474 -555,K53F,0.013198544,-0.00199763,0.024897989,-0.007659326,-0.136761276,0.013997776,0.047869068,-0.021471981,-0.020465021,0.020812491,-0.02480775,0.055591447,-0.00579547,-0.017910577,0.002591926,-0.09609753,-0.177425021,1.3339214,2.267983088,-3.935789151,-2.528354019,-3.14685318,-4.237520851,-5.894870804,-3.871346901,-4.366818806,-1.674313953 -556,K53I,-0.059441727,0.007738123,-0.009421033,0.015696018,-0.082011237,-0.033641695,-0.088118083,-0.03076537,0.053599258,0.025798899,-0.010322653,0.018454627,-0.037296692,0.044932336,-0.0135403,-0.017492817,-0.146529657,1.213423602,2.543383438,-3.391903246,-2.93918425,-2.905668076,-4.189300484,-4.680452446,-2.244910973,-4.805919927,-2.19597829 -557,K53H,-0.065100628,-0.039347872,-0.02010982,0.010362261,-0.066030242,-0.028571457,-0.078964468,-0.051236788,-0.037413018,0.026769838,-0.105465581,0.037938475,-0.078158114,0.021051093,-0.000326571,0.022568929,-0.154629412,1.139088154,2.66526459,-3.233080808,-2.931533089,-3.333809471,-2.617027153,-3.220897263,-4.062137062,-4.464857084,-1.617228506 -558,K53M,-0.056733006,0.017320324,0.029322215,0.016302164,-0.025403978,-0.053304177,-0.062466017,-0.050999995,-0.019572908,0.094394415,-0.059753768,0.087940174,-0.029295744,0.043990047,-0.011385719,0.08045969,-0.131267646,1.223759613,2.920356167,-3.303841693,-2.561312813,-3.458778595,-2.699389992,-4.230004951,-3.569722115,-4.881024965,-2.727055746 -559,K53L,-0.02775355,-0.007413932,0.008486077,0.031747423,-0.033696514,0.001724073,-0.026813953,-0.028693146,-0.004239953,0.040714184,-0.055542047,0.023775862,-0.006803709,0.041597233,0.021897613,0.014348283,-0.081741311,1.205919363,2.667881045,-2.297924609,-1.143322121,-2.323057243,-1.943709984,-3.252626701,-2.826906998,-4.010577778,-1.255735608 -560,K53N,0.035642862,0.018168551,0.045629047,0.046970098,0.000860667,-0.01870789,0.034037063,0.03724866,-0.08049769,0.019265653,0.017071448,0.042980804,0.048277289,0.021153968,0.072786227,0.024485302,-0.022763969,1.074974489,2.575935085,-2.397261484,-2.125000214,-2.067987778,-2.957359573,-2.22665036,-2.609309494,-3.156693437,-1.196900902 -561,K53Q,-0.064467582,-0.040891209,-0.015934848,0.008586941,-0.035956316,-0.017645888,-0.06853149,-0.060403674,0.010390316,-0.014352789,-0.067429629,0.045118061,-0.076987756,0.041913921,-0.024740039,0.026126846,-0.098039478,1.108603588,2.726266873,-0.352964899,-0.344955299,-0.733219315,-0.041185318,-0.50551049,-0.139954071,-0.834224945,-0.085470368 -562,K53P,-0.076456508,-0.014814132,-0.516393098,-1.630270531,-2.375736807,0.051281823,-0.057169639,-0.095743376,0.01044026,0.019469808,-0.049098072,-0.352982313,-0.679803882,-1.494469414,-1.766071648,-1.773683518,-2.977790096,3.569769943,2.583588016,-3.86512625,-3.395563881,-3.914318626,-3.748092941,-4.097907967,-4.169747833,-4.229257076,-1.606272485 -563,K53S,-0.050495171,-0.013098143,-0.005297299,0.035675001,-0.070319479,0.027581113,-0.054754125,-0.046236217,0.015286283,0.023627841,-0.049824127,0.047895201,-0.058489798,0.063364246,0.007985755,0.008632441,-0.149271398,1.071761897,2.58014253,-2.438742757,-2.611211914,-1.701146332,-2.925926697,-2.755948723,-2.199480118,-3.207808526,-0.987376957 -564,K53R,-0.033126553,-0.005835707,0.018994185,0.034880002,-0.020171097,-0.007097472,-0.053460443,-0.012792663,0.029693908,0.037751621,-0.049423034,0.071152919,-0.03316455,0.058622479,0.011137524,0.049797002,-0.090139196,1.154307607,2.830643716,-1.232863437,-0.420223816,-1.050185966,-0.747173271,-1.543588943,-2.403145187,-2.343706802,0.852563508 -565,K53T,-0.0477201,-0.018620372,-0.019365818,-0.004198577,-0.06812083,-0.018669861,-0.057383874,-0.038056325,0.074071227,-0.011596041,-0.025644703,0.009812796,-0.048544431,0.004545693,-0.012942846,-0.028857027,-0.107384632,1.254800696,2.432989606,-1.973463837,-1.965676559,-1.420248367,-2.254488731,-2.425480209,-1.801425316,-3.306855543,-0.725968494 -566,K53W,-0.05888709,-0.030869081,-0.028850659,-0.004639882,-0.735453025,0.043709099,-0.050507579,-0.0672666,-0.029797219,-0.00557943,-0.056158732,0.030685649,-0.088386967,0.027871359,-0.037151122,-0.44310342,-1.02780263,0.824814215,1.505509118,-1.656783841,-0.144984749,-1.519902435,-1.867578491,-2.889898605,-1.861554924,-3.88859761,-1.086243327 -567,K53V,-0.07460498,-0.014389252,-0.005017852,0.016363482,-0.041850368,-0.015458567,-0.077946146,-0.071263813,0.048483529,0.045191863,-0.073970367,0.067571733,-0.077607436,0.058003611,-0.025276648,0.033740572,-0.117441308,1.230449126,2.728448111,-2.64824884,-2.044095978,-2.233257408,-2.814561241,-4.28724659,-1.862082985,-3.72701349,-1.313983913 -568,K53Y,-0.046545851,0.012037014,0.031077342,0.040895084,-0.141820178,0.072669371,-0.034756429,-0.058335273,-0.027235548,0.034548816,-0.010474789,0.073665232,-0.011510548,0.062659527,0.01913064,-0.095741332,-0.187899024,1.215013415,2.290331455,-4.683560483,-3.460074326,-4.132097336,-4.862936409,-6.263318733,-4.69937561,-4.789992664,-2.160102434 -569,I54A,-0.023129063,-0.006890236,-0.005767954,0.04632831,-0.2974784,0.033000292,-0.012215021,-0.034043104,-0.012621712,-0.006911293,-0.006869178,0.013762576,-0.025298483,0.068074969,0.02458165,-0.199563203,-0.395393597,1.250853078,2.066913331,-2.267246861,-2.957902466,-3.077179306,-1.328187683,-2.018848045,-1.954116806,-2.542771461,0.383157929 -570,I54C,-0.040677478,-0.03869697,-0.031557143,-0.012448513,-1.22733725,0.022304435,-0.030096059,-0.051258897,-0.037283641,-0.047872767,-0.029521172,-0.025268088,-0.037846198,0.017022248,-0.041919274,-0.966743904,-1.487930595,0.804785647,1.372631672,-4.805729349,-4.977004959,-5.592247742,-3.947143883,-5.109667084,-4.402583076,-4.537176366,-1.941919415 -571,I54E,-0.038754576,-0.01499376,-0.00151274,0.027136531,-0.395029678,0.023081891,-0.02421874,-0.053290412,0.068783407,0.002231621,-0.032219141,-0.000123558,-0.002901921,0.067220573,-0.012947512,-0.27491695,-0.515142405,0.743402718,1.559155781,-1.833488882,-1.144862564,-2.624572769,-1.122601753,-1.331540314,-2.943867012,-2.858001758,1.363138377 -572,I54D,-0.056099368,-0.007939577,-0.021386905,-0.099723087,-1.606773511,-0.021766659,-0.037656155,-0.074542581,-0.008375658,0.014390567,-0.03026972,0.003933364,-0.046707174,0.021273647,-0.220719821,-1.604337277,-1.609209744,0.601184374,1.309185605,-4.692432782,-4.318589478,-6.501045753,-3.766563828,-2.819447647,-6.056517204,-4.568761098,-1.347296878 -573,I54G,-0.064542125,-0.014153108,-0.020052259,-1.232503314,-2.112324616,0.045723956,-0.029550329,-0.09953392,-0.033256371,-0.024280022,-0.004026194,-0.018590147,-0.021514371,-0.939124646,-1.525881981,-1.978285706,-2.246363526,2.207125432,1.559193934,-3.690598213,-4.386127693,-4.941524788,-2.67427462,-2.878135521,-3.572928444,-3.56936914,-0.724411576 -574,I54F,0.015921842,0.021441281,0.034468634,0.052441101,-0.063526157,-0.026463137,0.021186948,0.010656736,0.007404911,-0.035732059,0.07861462,0.005349172,0.063588096,0.082583779,0.022298423,-0.074300618,-0.052751695,1.411304952,2.545440026,-3.708910501,-3.58673307,-4.461830566,-3.290943451,-3.84006131,-3.364984108,-4.16432868,-1.183682896 -575,I54H,-0.031823121,0.037092671,0.000915216,0.073679167,-1.122305108,-0.016733451,-0.022512675,-0.041133566,0.029778063,0.111677063,-0.037491722,0.055062555,-0.053232123,0.147215269,0.000143065,-0.919748754,-1.324861462,0.482941623,1.3387003,-4.540031844,-4.054198463,-5.132406357,-3.916039421,-4.330929718,-5.266585258,-3.299079692,-0.739124084 -576,I54K,-0.054961239,0.017675841,-0.005080623,0.046059257,-1.522346732,0.050857354,-0.010579405,-0.099343072,0.081414483,0.021503731,0.013847951,0.045432784,-0.05559403,0.089636447,0.002482066,-1.260824181,-1.783869282,0.667896291,1.331573594,-2.893139641,-3.948876595,-2.323361916,-2.456528549,-2.794453552,-2.942477592,-3.244820655,-0.371225744 -577,I54M,-0.002580459,-0.008294738,0.021083792,0.022339234,-0.002939038,-0.047335045,-0.017696651,0.012535733,0.020596591,0.000889002,-0.017478478,0.07424481,-0.032077227,0.073127598,-0.028449131,-0.006186008,0.000307932,1.155632099,2.637126711,-1.578486365,-1.949879761,-1.269700417,-1.856499863,-1.445266449,-1.371085335,-2.713101529,-1.371446203 -578,I54L,-0.04230915,-0.026016008,-0.014166538,0.032575887,-0.097294124,-0.011744482,-0.040702335,-0.043915965,-0.005682094,0.000416062,-0.052448077,0.026907332,-0.055240407,0.080893247,-0.015741474,-0.066205396,-0.128382852,1.201765173,2.357535951,-0.027791203,-0.104934784,-0.068961151,0.14095536,0.128820366,-0.234835808,-1.361186622,-0.025450677 -579,I54N,-0.027288073,-0.003836882,0.017648614,0.036042556,-1.680709597,0.017065763,-0.015296159,-0.039279986,-0.015288952,-0.028626322,0.020952559,0.065891453,-0.030594226,0.11125923,-0.039174118,-1.591052382,-1.770366812,0.456891098,1.306335875,-3.873269955,-3.705882492,-4.78084462,-3.456992767,-2.525085762,-4.897544136,-3.553138795,-1.060508641 -580,I54Q,-0.058182689,-0.032744167,-0.001035358,0.037605258,-0.866461944,0.020938274,-0.055347837,-0.06101754,-0.021254654,-0.027866815,-0.037621518,0.010586818,-0.012657533,0.052196678,0.023013838,-0.574913876,-1.158010012,0.745198766,1.433223734,-2.902590553,-2.931452034,-3.315317421,-2.340028564,-2.390098625,-3.536056122,-3.615745259,0.107905765 -581,I54P,-0.044711657,-0.010474349,0.010979219,0.030636419,-0.990800176,0.02849679,-0.039675768,-0.049747546,0.007678334,0.003458245,-0.024406942,0.048661648,-0.02670321,0.083699466,-0.022426628,-0.768814156,-1.212786196,0.703797837,1.38428326,-5.194536037,-4.761108719,-5.421281387,-4.886559425,-5.509677406,-5.394053246,-4.795443756,-1.303730615 -582,I54S,-0.081304748,-0.019553986,-0.025621694,0.007173218,-1.302305709,0.022727181,-0.072305048,-0.090304447,0.084872428,0.019342173,-0.058450144,0.020961979,-0.072205366,0.09607506,-0.081728625,-1.095735628,-1.50887579,0.835960793,1.365554163,-1.984482954,-2.003571884,-2.631519249,-1.599689621,-1.59644532,-2.091188698,-2.195178775,1.001114195 -583,I54R,-0.070541357,-0.022241653,-0.015986349,0.022199842,-1.209600931,0.015964767,-0.043472893,-0.09760982,-0.037402063,0.005488925,-0.04997223,0.042616905,-0.074589603,0.090810106,-0.046410422,-0.787272462,-1.6319294,0.476593724,1.346132877,-2.678515073,-2.712096268,-2.762939949,-1.810704674,-3.083763298,-3.023071175,-2.777154354,0.791897016 -584,I54T,0.00801054,0.000297606,0.01587093,0.065095842,-0.017431717,-0.004542954,0.000210475,0.015810604,-0.020010752,0.008671234,-0.008076022,0.016806019,0.014935841,0.077923265,0.052268419,-0.029351006,-0.005512428,1.361151851,2.636384469,-0.68440593,-1.317123375,-1.944217659,0.356044594,-0.244181152,-0.272552055,-1.718445747,1.797220981 -585,I54W,-0.148268344,-0.030851699,-0.03509277,0.023610868,-0.33586407,-0.01612227,-0.059334843,-0.237201844,0.007242077,-0.019170533,-0.042532864,0.006036301,-0.076221841,0.058713405,-0.01149167,-0.232936559,-0.438791581,1.327525996,2.026920352,-4.834102219,-4.479171043,-6.140109909,-3.861424606,-4.615488319,-5.074317215,-4.225568134,-1.918368784 -586,I54V,-0.020032888,-0.002041864,0.025395617,0.068283713,0.054009757,-0.01513863,-0.034581529,-0.005484247,0.003448044,0.02362648,-0.027710207,0.082294178,-0.031502944,0.125583498,0.010983927,0.084655709,0.023363804,1.127534701,2.963893093,-0.106620937,-0.059003799,-0.536916435,0.256526619,-0.192865402,-0.000845665,-1.789068082,0.402494513 -587,I54Y,0.000893866,0.000170567,0.041784093,0.051552871,-0.862369383,-0.047665091,-0.008414305,0.010202036,0.02026095,0.033811189,-0.033470055,0.100694486,-0.017126301,0.108501919,-0.005396177,-0.668245723,-1.056493042,0.477423959,1.360606119,-4.615511594,-4.280406967,-5.684105682,-3.988009659,-4.415904877,-4.709130783,-3.519965169,0.070656499 -588,L55A,-0.043946162,-0.000406832,-0.017659964,-0.048648706,-1.620167459,-0.018545564,-0.022917889,-0.064974435,0.032860316,0.02843301,-0.029246674,0.001784491,-0.037104418,-0.016624178,-0.080673233,-1.423148544,-1.817186373,0.738243363,1.332343679,-3.409137782,-2.092425934,-6.364892265,-3.681854874,-2.750774101,-2.155741737,-3.549245343,-1.005307657 -589,L55C,0.028029463,0.001886246,0.002193797,-0.00701446,-1.470231069,0.048476978,0.06000908,-0.003950154,0.014303419,-0.05532243,0.059094922,0.052632139,-0.048244546,0.062222867,-0.076251787,-1.393185321,-1.547276816,0.247100085,1.304887879,-6.663730322,-6.145329613,-7.441542168,-7.006262711,-5.689711372,-7.035805748,-5.63049685,-3.721709141 -590,L55E,-0.078308734,-0.011803782,-0.017035184,-0.062833403,-1.114443659,0.019067549,-0.082804468,-0.073812999,0.072972759,-0.044920472,0.021312908,-0.011197608,-0.022872759,-0.0797144,-0.045952405,-1.00598219,-1.222905128,0.95321184,1.39677537,-6.569337236,-6.498293045,-8.704575348,-7.190007866,-5.440958405,-5.012851517,-5.185668956,-4.339928325 -591,L55D,-0.097568585,0.007447266,-0.009581961,-1.194058291,-2.571945359,-0.028671237,-0.077885283,-0.117251887,0.039101927,0.019593289,-0.004698758,0.012425044,-0.031588966,-0.779251136,-1.608865445,-2.166373152,-2.977517565,1.839895064,1.374642484,-7.316120255,-6.170497795,-11.01929231,-7.725750664,-5.85398597,-5.811074532,-5.712419656,-4.416674351 -592,L55G,-0.062744679,0.004591223,-0.002486328,0.009567455,-1.61012303,0.039326443,-0.040691204,-0.084798153,0.024217107,0.018148048,-0.008965603,0.048985457,-0.053958113,0.05550795,-0.03637304,-1.60504985,-1.615196209,0.554420618,1.308223206,-7.622554494,-7.020751228,-9.847201843,-8.187922455,-6.942603996,-6.114292946,-6.166130805,-5.051864209 -593,L55F,0.029728566,0.054367623,-0.018843382,0.001653209,-0.209352289,-0.02730735,0.030207291,0.02924984,-0.000445936,0.004441945,0.104293301,-0.062973493,0.025286729,-0.053825168,0.057131585,-0.18810131,-0.230603267,1.495308765,2.191795125,-2.765576958,-2.179935318,-3.14322728,-4.269937363,-2.375571709,-1.85921312,-4.093077741,-0.618096223 -594,L55I,0.015801092,0.025449447,0.017765421,0.038509523,-0.013824586,-0.000490329,-0.012705897,0.044308081,0.13521373,-0.06088898,0.111787873,-0.011163983,0.046694824,0.015873963,0.061145082,-0.02845489,0.000805718,1.18803743,2.483375335,-2.124960611,-2.02143103,-4.005187439,-2.734849815,-1.305807541,-0.557527229,-3.131091544,-0.099015248 -595,L55H,0.01967476,0.024327373,0.034673711,0.011815338,-0.720452442,-0.002208673,0.05921104,-0.01986152,-0.027649988,0.017525046,0.031129699,0.063256629,0.006090792,0.029038291,-0.005407615,-0.510697338,-0.930207546,0.522433189,1.390179118,-4.991145511,-3.741222977,-6.098104919,-6.061464691,-4.680322037,-4.37461293,-4.816604959,-3.581706595 -596,L55K,-0.016362383,0.062781488,0.066615652,-0.005006381,-0.806127199,-0.006896957,-0.035483519,0.002758754,0.021047552,0.05680163,0.068761346,0.067074075,0.066157229,0.029550235,-0.039562996,-0.599181824,-1.013072573,0.684510944,1.412167555,-7.41201237,-7.192982109,-9.069798279,-6.974298843,-6.025270821,-7.7977118,-7.04608472,-5.444832432 -597,L55M,-0.048998703,-0.017679516,-0.054487304,-0.027730247,-0.067702575,0.030070307,-0.038735289,-0.059262116,0.184987551,-0.0811261,0.045767068,-0.001968984,-0.107005624,-0.039165036,-0.016295457,-0.014880276,-0.120524873,1.194388358,2.506278758,-3.580665215,-3.744216919,-3.848321495,-4.021985176,-3.430395683,-2.858406799,-4.156214179,-2.71152068 -598,L55N,-0.004519032,0.047251744,0.010384456,0.008009066,-1.526032982,0.028973415,-0.003045079,-0.005992984,-0.012879236,0.054138411,0.040365077,0.032661058,-0.011892147,0.013695244,0.002322888,-0.949487822,-2.102578141,0.707327327,1.360075543,-7.07943243,-6.960560219,-8.420739624,-7.976489433,-5.883748665,-6.155624207,-6.339875677,-5.494911914 -599,L55Q,-0.030800542,0.073817553,-0.011402408,0.025562421,-1.22558591,0.038036572,-0.001181516,-0.060419568,-0.00729134,0.087080179,0.060554927,0.039538207,-0.062343022,0.020181424,0.030943418,-0.857366523,-1.593805296,0.879612922,1.405673265,-5.237211339,-5.143525719,-6.653509102,-5.608140114,-4.085807777,-4.695073982,-5.20501748,-4.156817107 -600,L55P,-0.020048331,-0.073588737,-1.459205261,-2.094896712,-2.604961843,0.024842976,0.025423424,-0.065520086,0.022889362,-0.043335947,-0.103841526,-1.433859114,-1.484551408,-2.059534637,-2.130258786,-2.401333674,-2.808590012,2.937614746,1.353990018,-8.306996106,-7.403308128,-10.43497247,-7.890239769,-7.440086792,-8.366373367,-6.456354577,-4.046014867 -601,L55S,-0.065589886,-0.003168726,0.004811972,-0.030178609,-2.021762852,0.001485089,-0.046266743,-0.084913029,0.01036546,-0.022642048,0.016304596,0.035720926,-0.026096983,0.004298917,-0.064656135,-1.523067271,-2.520458432,0.654592339,1.316922059,-4.876852455,-4.213934975,-5.719207542,-6.152587685,-4.446965332,-3.851566742,-4.626384448,-3.379882591 -602,L55R,-0.010344307,0.011764167,0.028966117,-0.007640521,-0.520211329,-0.004925605,0.000453682,-0.021142296,0.020842744,-0.007362018,0.030890351,0.049785939,0.008146295,-0.001863043,-0.013417999,-0.304533103,-0.735889554,1.09015979,1.744353881,-4.144089966,-3.55778981,-4.818662918,-4.186270409,-3.938962296,-4.218764397,-4.084569518,-3.903406227 -603,L55T,-0.017072321,0.009161771,0.004390845,-0.019588093,-0.997385307,0.005182841,-0.029033215,-0.005111427,0.011094964,-0.012541387,0.030864929,0.020994421,-0.012212732,-0.007400788,-0.031775398,-0.586842842,-1.407927772,0.8429768,1.453456549,-3.487301445,-3.175902016,-4.727523727,-4.080710945,-2.831628395,-2.620742142,-2.903465446,-2.497732234 -604,L55W,-0.060346077,0.047085736,0.03714705,-0.014491092,-1.28202634,-0.018202402,-0.070586956,-0.050105198,-0.002847116,0.066037966,0.028133506,0.062576077,0.011718023,-0.024152103,-0.004830081,-1.172978518,-1.391074161,0.521021073,1.3252469,-2.687455287,-1.47247052,-4.486818504,-2.822579506,-2.637441612,-2.017966293,-2.797015375,-1.058120958 -605,L55V,0.014991166,0.081244323,0.060572757,0.02313431,-0.049845221,-0.004909117,-0.022182547,0.052164878,0.036503158,0.081558681,0.080929965,0.096029484,0.025116029,0.016275226,0.029993394,-0.043165458,-0.056524984,1.365369387,2.637889291,-2.595099638,-1.768907814,-4.709221512,-3.308373581,-2.097502167,-1.091493118,-2.271989622,0.353714244 -606,L55Y,-0.019376263,0.00380908,0.036430464,-0.005424249,-0.120999362,-0.016813688,-0.027238701,-0.011513825,0.048041515,0.017675425,-0.010057266,0.063475005,0.009385922,-0.007743363,-0.003105134,-0.084773372,-0.157225351,1.272755985,2.290210922,-4.279370291,-3.188171608,-4.103879044,-5.847480469,-3.707082947,-4.550237389,-4.011470481,-1.385643533 -607,E56A,-0.007075149,-0.045329982,-0.048318462,-0.013853827,-0.087059359,-0.024787014,-0.019267115,0.005116818,0.154452737,-0.055201609,-0.035458355,-0.084661397,-0.011975527,-0.07102575,0.043318096,-0.137520327,-0.03659839,1.411536598,2.222463606,,,,,,,, -608,E56C,-0.105680933,-0.043289752,-0.104420778,-0.107748186,-1.555378918,0.07930635,-0.103605737,-0.107756129,0.033998367,0.007584677,-0.09416418,-0.082322322,-0.126519233,-0.063211844,-0.152284527,-1.485573511,-1.625184324,0.852608431,1.33210435,,,,,,,, -609,E56D,0.049706364,-0.001656966,-0.02204443,0.01783075,-0.058707709,-0.033508049,0.0477528,0.051659928,0.012560391,0.01139915,-0.014713081,-0.058771828,0.014682968,-0.020242648,0.055904148,-0.061992153,-0.055423265,1.440886626,2.531283859,,,,,,,, -610,E56G,0.013852202,-0.037260837,-0.04457583,0.022340571,-0.051919235,-0.014671097,0.004696482,0.023007922,0.146940447,-0.045369904,-0.02915177,-0.102633169,0.013481509,-0.019784094,0.064465236,-0.069300336,-0.034538134,1.174965431,2.220837145,,,,,,,, -611,E56F,-0.014309734,-0.022002683,-0.040042314,-1.272702414,-2.440835188,-0.042179322,0.00312856,-0.031748028,-0.021471825,-0.016889804,-0.027115562,-0.05630751,-0.023777118,-0.844470432,-1.700934396,-2.320253123,-2.561417252,1.88586285,1.321685566,,,,,,,, -612,E56I,-0.011515885,-0.047164518,-0.045670434,-0.753472666,-2.18407722,-0.022711535,-0.009558316,-0.013473454,0.001695094,-0.037919854,-0.056409181,-0.111194924,0.019854056,-0.524001804,-0.982943528,-1.895568781,-2.472585659,1.713301672,1.407107819,,,,,,,, -613,E56H,-0.070809657,-0.063213294,-0.092155841,-0.051924339,-1.177880662,-0.0177034,-0.06433672,-0.077282594,0.045289532,-0.007392224,-0.119034364,-0.061103453,-0.123208229,-0.047572653,-0.056276025,-0.899108727,-1.456652597,0.752424048,1.376908649,,,,,,,, -614,E56K,0.015647325,0.007614162,-0.020991929,0.011995589,-0.101755554,0.006501686,0.016416934,0.014877715,0.048776654,-0.002774055,0.018002379,-0.029402852,-0.012581006,-0.05459101,0.078582188,-0.141318977,-0.062192131,1.438046943,2.254842547,,,,,,,, -615,E56M,-0.067963536,-0.059961332,-0.067191928,-0.012326942,-1.303131735,-0.003275111,-0.070221294,-0.065705778,0.176413373,-0.009629253,-0.110293411,-0.0832292,-0.051154656,-0.00150631,-0.023147574,-1.205562615,-1.400700855,0.888978474,1.360993919,,,,,,,, -616,E56L,-0.029492049,-0.028623201,-0.02261759,0.006626346,-1.314274174,-0.006761121,-0.0228224,-0.036161698,0.064237044,0.006708924,-0.063955326,-0.034685753,-0.010549427,-0.014150614,0.027403305,-1.023143044,-1.605405304,0.735594566,1.358527951,,,,,,,, -617,E56N,-0.061491337,-0.099418736,-0.029372518,-0.008609457,-0.101191244,-0.05807229,-0.083730081,-0.039252593,0.055156436,-0.045307234,-0.153530237,-0.002892315,-0.055852721,-0.010367395,-0.006851519,-0.078147535,-0.124234952,1.30780079,2.332575042,,,,,,,, -618,E56Q,-0.068666217,-0.070112779,-0.09635936,-0.033419068,-0.131065951,-0.042763784,-0.074507563,-0.062824871,0.11004822,-0.040794859,-0.099430699,-0.108800832,-0.083917887,-0.043994499,-0.022843636,-0.126039188,-0.136092714,1.367618085,2.189172252,,,,,,,, -619,E56P,-0.012698869,-1.267404922,-2.061123294,-2.326231925,-2.66658801,0.01438047,0.017659253,-0.043056991,0.034611594,-1.152267954,-1.382541889,-2.257040859,-1.865205728,-2.032429493,-2.620034356,-2.518280579,-2.81489544,0.24743072,-0.718369061,,,,,,,, -620,E56S,-0.000711133,-0.017403851,-0.041781813,0.015782653,-0.092556475,-0.028021957,-0.007383648,0.005961382,0.064406007,0.008578458,-0.04338616,-0.053848953,-0.029714672,-0.010584885,0.042150191,-0.099030323,-0.086082627,1.238890577,2.226796056,,,,,,,, -621,E56R,0.011447021,-0.006710533,-0.029918323,-0.026677064,-0.221984209,-0.009670921,0.027226743,-0.004332702,0.027233921,0.009520699,-0.022941765,-0.040526953,-0.019309693,-0.049998792,-0.003355336,-0.228733277,-0.215235141,1.337635894,2.005808318,,,,,,,, -622,E56T,-0.020475445,-0.038487431,-0.028395944,-0.000967769,-0.103973384,-0.08167141,-0.039240654,-0.001710235,0.067373955,-0.003981772,-0.07299309,-0.016308431,-0.040483457,-0.009082046,0.007146509,-0.083237494,-0.124709274,1.36053415,2.349029252,,,,,,,, -623,E56W,-0.014720088,-0.046734506,-0.201240581,-0.649261405,-2.094695901,0.024715932,0.026222512,-0.055662688,-0.011487604,-0.144791744,0.051322733,-0.301593649,-0.100887512,-0.498586209,-0.7999366,-1.847264102,-2.342127699,1.895762031,1.487995674,,,,,,,, -624,E56V,-0.04984681,-0.044497681,-0.042798562,-0.001796628,-1.128714536,0.017311442,-0.038936269,-0.060757351,0.070317786,0.000519606,-0.089514967,-0.030148133,-0.055448991,-0.019360477,0.015767222,-0.960312342,-1.29711673,0.784033348,1.37230954,,,,,,,, -625,E56Y,-0.043523652,0.025877865,0.017042042,-0.349638708,-1.791599132,0.042423776,-0.03035837,-0.056688933,0.059616927,0.046011241,0.005744488,-0.005103774,0.039187858,-0.268313508,-0.430963907,-1.745390669,-1.837807595,1.349598916,1.370011459,,,,,,,, -626,S57A,0.036340484,-0.004586517,0.03007834,-0.000883725,0.025721015,0.031624471,0.016102774,0.056578194,-0.035629375,-0.026064198,0.016891164,0.006141302,0.054015378,-0.01946162,0.017694171,-0.046749139,0.098191168,1.379925886,2.505310835,-1.377781865,-1.099274887,-1.993630531,-0.524309174,-1.127201965,-2.144492767,-2.723105792,0.122921169 -627,S57C,-0.115665714,-0.013955769,-0.051785959,-0.057806418,-1.504226134,0.145683596,-0.072253158,-0.159078269,0.111166846,-0.050212967,0.02230143,-0.011094171,-0.092477747,-0.065923019,-0.049689817,-1.27294584,-1.735506427,0.916078152,1.357990546,-5.841584,-4.677781075,-6.4557481,-5.122833244,-6.984110603,-5.967446976,-6.178315284,-2.993184007 -628,S57E,0.043007583,-0.051736179,-0.02321338,-0.024460533,0.005882297,0.051438362,0.095171462,-0.009156296,0.034711129,-0.106342874,0.002870517,-0.031076853,-0.015349906,-0.047930788,-0.000990277,-0.054090073,0.065854666,1.457366753,2.562356699,-2.615928589,-1.282341995,-1.852585655,-3.476698189,-3.318602081,-3.149415024,-3.940574859,-0.838964677 -629,S57D,0.012117977,-0.025854208,-0.014948584,-0.018968414,-0.976962278,0.144862333,0.027780004,-0.003544051,0.016151053,-0.043254581,-0.008453834,-0.057893672,0.027996505,-0.06153611,0.023599283,-0.661296904,-1.292627651,0.8754014,1.444372617,-3.485150319,-2.612180962,-2.765914429,-3.857658485,-3.424132568,-4.76586515,-4.421185363,-1.068017849 -630,S57G,0.02325097,0.026386692,-0.017013242,-0.019903022,-0.036135834,0.076971864,0.026333981,0.020167958,0.048034276,-0.052249883,0.105023266,-0.041878833,0.007852349,-0.0497311,0.009925056,-0.087966538,0.015694871,1.353534257,2.300723294,-0.938341794,-0.746865417,-1.29488813,-0.613921997,-0.63042868,-1.405604744,-1.83041303,0.22230893 -631,S57F,-0.00194961,0.013476406,0.051840073,0.015182699,-0.258372422,0.008782859,0.016264959,-0.020164178,0.046427148,-0.0041582,0.031111012,0.053146407,0.050533739,0.02456273,0.005802668,-0.195234379,-0.321510465,1.265665564,2.023197908,-5.73285892,-3.422742661,-5.787638306,-5.219929939,-7.156373909,-7.077609787,-5.429482614,-2.23125306 -632,S57I,-0.039722372,-0.033439109,-0.039665635,-0.033138512,-1.225007314,0.087657125,0.030985571,-0.110430315,-0.130530198,-0.052825848,-0.01405237,-0.020779534,-0.058551736,-0.053164275,-0.013112748,-1.133064599,-1.316950029,1.062855707,1.403206383,-7.176854854,-5.531678597,-8.303977844,-6.163407082,-8.382250053,-7.502960693,-6.289185336,-3.797157595 -633,S57H,0.010871542,-0.014677906,-0.000915884,-0.007518133,-0.200224732,0.031863932,0.03318333,-0.011440246,0.083583325,-0.017047207,-0.012308604,-0.043106758,0.04127499,-0.015843754,0.000807488,-0.164247487,-0.236201976,1.339313391,2.117806775,-4.453052979,-3.345781906,-4.532512665,-4.764303871,-4.443329887,-5.179336563,-4.356326686,-2.571637151 -634,S57K,0.031551834,0.015012525,-0.008086395,0.013220865,-0.040180196,0.049263309,0.046846961,0.016256707,-0.001339926,-0.014531819,0.044556868,0.003363119,-0.019535909,0.00751213,0.018929599,-0.103802443,0.023442051,1.386744168,2.397738353,-5.076596799,-4.708790337,-4.992588829,-4.516917068,-6.415753563,-4.748934196,-4.945336455,-2.548374021 -635,S57M,-0.091014005,-0.07920851,-0.039079847,-0.072252579,-0.128876766,0.048469955,-0.093113885,-0.088914124,0.049035021,-0.093529427,-0.064887592,-0.055705927,-0.022453766,-0.039905013,-0.104600144,-0.117889867,-0.139863664,1.507092754,2.379889094,-6.463851408,-5.368222946,-6.463892723,-5.281755821,-7.80404232,-7.401343231,-6.392507831,-3.028457468 -636,S57L,-0.007037969,-0.008045191,-0.008061671,-0.010023526,-0.638674441,0.032398866,0.038249579,-0.052325516,0.062711736,-0.018508382,0.002418,0.005021789,-0.02114513,-0.015982155,-0.004064896,-0.452130988,-0.825217894,0.920949279,1.525789304,-4.97456615,-3.056441925,-4.656159264,-3.794424751,-7.705344902,-5.660459908,-4.680247137,-1.36518123 -637,S57N,-0.025358027,-0.017188854,-0.019736104,-0.019631752,-0.340335844,0.045646191,-0.002049429,-0.048666625,0.0624721,-0.011587857,-0.02278985,-0.01149832,-0.027973887,-0.014710408,-0.024553095,-0.232219919,-0.448451768,1.146066182,1.844217246,-3.282030991,-3.242335609,-3.457667831,-3.602670052,-2.677920578,-3.429560883,-3.842241143,-1.655055995 -638,S57Q,0.048736563,-0.029655164,-0.032662049,-0.016072632,-0.0140985,-0.023760243,0.050507502,0.046965623,0.017934315,-0.077683923,0.018373596,-0.03736447,-0.027959628,-0.04862179,0.016476527,-0.053721881,0.025524882,1.406656401,2.445028632,-3.380341451,-2.33595459,-2.978841911,-3.705413445,-3.813675407,-4.067821899,-3.937204181,-1.551160695 -639,S57P,-0.039144589,-0.011819021,-1.32400264,-2.119650989,-2.61056601,0.051998948,-0.007547331,-0.070741847,0.02570305,-0.00523472,-0.018403322,-1.134828533,-1.513176746,-2.161050864,-2.078251113,-2.523598587,-2.697533433,2.098460884,0.747681459,-8.57026028,-7.59972274,-8.839180573,-7.886295692,-9.588770103,-8.937332291,-9.233522517,-8.524726012 -640,S57R,-0.020317261,-0.026390838,-0.004827167,-0.0000363,-0.129307108,0.064040284,-0.025159072,-0.015475449,0.004082249,-0.014339355,-0.03844232,0.001039392,-0.010693726,0.017067651,-0.017140261,-0.121326308,-0.137287907,1.341335418,2.224991218,-4.712526955,-3.763487228,-4.760721443,-4.514400291,-5.750427795,-4.773598015,-4.84238626,-1.94624208 -641,S57T,0.005376947,-0.018162997,0.003326203,-0.001019837,-0.065115516,0.024178548,0.009672883,0.001081011,0.048341563,-0.030015497,-0.006310496,0.023308462,-0.016656056,-0.052996614,0.05095694,-0.107990163,-0.022240869,1.406996772,2.297770792,-2.320858521,-1.804358337,-3.126137726,-1.566615379,-2.378113152,-2.729068008,-2.541281294,-0.821961756 -642,S57W,-0.035707871,0.010650809,0.014304718,-0.007609767,-0.495673855,-0.075358136,-0.065090821,-0.006324921,0.03362802,0.024866069,-0.003564451,0.031550084,-0.002940648,-0.002795061,-0.012424472,-0.382514407,-0.608833303,0.803532167,1.532618686,-8.917248959,-6.810054909,-9.489147163,-8.50209655,-10.20008459,-9.58486158,-8.325882829,-6.236506034 -643,S57V,-0.052295893,-0.013614678,0.0218317,0.016770773,-0.09729119,0.077022636,0.012746252,-0.117338038,0.07914694,-0.034573968,0.007344613,0.026772543,0.016890857,0.010089846,0.0234517,-0.120745907,-0.073836472,1.353746715,2.270184497,-5.244703833,-3.643005608,-6.570448586,-4.323586739,-5.831363373,-5.855114861,-5.231396782,-2.111601777 -644,S57Y,-0.004951861,-0.002948246,-0.03655248,-0.02762638,-0.395671023,0.002009097,-0.010081703,0.000177981,0.020931024,-0.015919478,0.010022987,-0.013956151,-0.059148808,-0.046205009,-0.009047751,-0.301327178,-0.490014867,1.464995596,2.025613534,-6.054247644,-3.417466682,-6.355225662,-5.651023262,-7.430377235,-7.417145378,-6.279595541,-2.683717596 -645,F58A,0.053703426,0.023405916,0.006317483,0.043638361,-0.096847901,0.037978173,0.035870629,0.071536222,-0.214490491,0.000774834,0.046036998,0.005406816,0.00722815,-0.012274535,0.099551257,-0.103416191,-0.09027961,1.436732134,2.375580792,-3.601323674,-4.760767685,-2.172290977,-4.741536133,-1.095916397,-5.236107178,-3.4126749,-1.859468689 -646,F58C,0.075695117,0.1183562,0.025289073,0.096241539,-1.092346968,0.068389652,0.123280484,0.028109749,-0.164393843,0.049370243,0.187342157,0.027868082,0.022710064,0.075846578,0.116636499,-1.214246308,-0.970447628,0.566730282,1.327073725,-4.026518883,-4.708851379,-2.905722679,-3.825254005,-3.605151947,-5.087614403,-4.011841565,-3.777496511 -647,F58E,0.031287255,0.03264178,-0.028907431,-0.660428802,-1.961057663,0.05576786,0.044749375,0.017825135,-0.144790998,-0.01923441,0.084517969,-0.055454698,-0.002360164,-0.355366551,-0.965491053,-1.946421665,-1.975693661,1.496216203,1.361844319,-3.368897084,-3.902692886,-1.572657204,-5.056076889,-2.169550552,-4.143507889,-3.204229822,-2.473618145 -648,F58D,0.05737005,0.113863443,-1.054667056,-1.816713315,-2.678411367,0.088615985,0.122826564,-0.008086464,-0.1467305,0.093683708,0.134043177,-0.829809572,-1.27952454,-1.790243757,-1.843182872,-2.759267799,-2.597554935,2.163161984,0.994874422,-4.877436206,-6.121414536,-2.91999427,-5.286204163,-3.901864677,-6.157703384,-4.183316898,-3.227637785 -649,F58G,0.042318228,0.069921796,0.023864113,-1.070042724,-2.34256389,0.055180123,0.054546448,0.030090007,-0.194720119,0.019081443,0.120762148,0.00796039,0.039767835,-0.600708877,-1.53937657,-2.110687727,-2.574440053,1.685252483,1.345426249,-5.984155087,-6.581969765,-3.553832542,-6.9792631,-4.770409866,-8.035300163,-5.678218104,-5.147866599 -650,F58I,0.065054418,0.071619853,0.037203604,0.04339302,-1.14552304,0.035935407,0.038936587,0.091172248,-0.294190571,-0.015772413,0.159012119,-0.025114179,0.099521387,0.036338037,0.050448002,-0.997143994,-1.293902086,0.716145415,1.356803146,-2.464877974,-2.675883888,-4.279448097,-2.577115967,-2.23680085,-0.555141068,-3.00572788,0.999320566 -651,F58H,0.086669164,-0.000310913,-0.047290163,0.025494098,0.026093905,0.039187741,0.083113652,0.090224676,-0.178163608,-0.102765758,0.102143932,-0.123287425,0.028707099,-0.09938977,0.150377965,-0.066018359,0.118206169,1.382333044,2.369509033,1.241556398,1.279864029,2.768740219,1.369929222,1.156203423,-0.366954903,-0.770213326,1.103905254 -652,F58K,0.057462835,0.11377443,0.059767707,0.121973303,-1.637460288,0.055411401,0.084686313,0.030239357,-0.268232033,0.082479151,0.145069709,0.077728852,0.041806561,0.113479114,0.130467491,-1.498997603,-1.775922973,0.580756037,1.314514043,-2.973144965,-3.316693634,-0.12025032,-5.144599617,-3.119409004,-3.164772247,-3.782699628,-1.960582425 -653,F58M,0.042891017,0.064612983,-0.002764882,0.071615347,-0.179274328,-0.005506384,0.022457313,0.06332472,-0.267023333,0.072086429,0.057139536,0.008651723,-0.014181486,0.056058984,0.08717171,-0.167584979,-0.190963676,1.2152938,2.077279764,-3.647243138,-3.775153877,-4.139557571,-3.329104355,-3.347574959,-3.644824928,-3.309712984,-1.89479711 -654,F58L,0.038395635,0.058953151,0.018928704,0.091389396,-0.463029668,0.039074454,0.045157203,0.031634066,-0.150842194,0.014960128,0.102946174,0.056312899,-0.018455491,0.078681844,0.104096948,-0.289322433,-0.636736902,0.629248339,1.523176922,-2.291952379,-2.358106621,-3.015200539,-1.315782028,-2.525645004,-2.245027702,-2.638040973,0.372004069 -655,F58N,0.067507906,0.071273244,0.036423784,0.119450076,0.020832937,0.004742411,0.044497905,0.090517906,-0.16243723,0.056974479,0.085572008,0.005013556,0.067834011,0.063813903,0.175086249,0.050482438,-0.008816565,1.151746493,2.848948091,-1.839786748,-2.3987015,0.309981918,-2.393475304,-2.021802216,-2.694936638,-1.995937381,-2.175855606 -656,F58Q,0.02762736,0.052770797,0.010679443,0.042182075,-0.396714012,0.030971119,0.03494434,0.020310379,-0.213886017,-0.005603582,0.111145176,0.005901285,0.015457601,0.009050524,0.075313625,-0.2698851,-0.523542923,1.540576869,2.131264544,-1.839245314,-1.20944281,-0.144272171,-2.635814644,-1.509096504,-3.697600441,-1.941657243,-1.820499462 -657,F58P,0.025621697,-1.655874927,-2.136885028,-2.19248557,-2.953853896,0.078188883,0.053294155,-0.002050761,-0.306515383,-1.794212229,-1.517537624,-2.221950925,-2.05181913,-2.210098098,-2.174873041,-2.860363376,-3.047344416,0.139921894,-1.216079974,-6.839248616,-7.076975433,-5.561164597,-7.385935989,-5.734165955,-8.438001106,-6.528542936,-6.766144588 -658,F58S,0.030074318,0.042791256,-0.009680112,0.075776546,-0.123861973,0.014903401,0.025583561,0.034565075,-0.19837834,0.009620063,0.075962448,-0.00177636,-0.017583864,0.043656729,0.107896362,-0.092954131,-0.154769815,1.290096231,2.319377947,-2.401836443,-3.914693977,-0.335484695,-3.178341743,-1.068517494,-3.512144302,-2.760671447,-1.880404534 -659,F58R,0.021534511,0.035974863,0.005343663,0.063960018,-0.371947743,0.031782736,0.023285645,0.019783376,-0.194642231,0.027035007,0.044914719,0.022990763,-0.012303437,0.059738771,0.068181265,-0.26909844,-0.474797046,1.538419356,2.091996821,-1.855895274,-1.279982018,-0.815947968,-1.655229279,-2.041828987,-3.486488121,-1.746525311,-0.789678838 -660,F58T,0.016727221,0.032433079,-0.0495138,0.060836745,-1.400821192,0.05151606,0.017421324,0.016033117,-0.173456502,-0.020093992,0.084960149,-0.035475117,-0.063552483,0.012890631,0.108782859,-1.127951885,-1.673690498,0.654679678,1.339868359,-3.58893017,-3.800898064,-2.491179779,-4.285511642,-2.258207703,-5.108853661,-3.337422292,-2.518604133 -661,F58W,0.097898921,0.073112629,0.051253868,0.090480436,0.038062554,0.044609526,0.109260058,0.086537783,-0.230368578,0.026480551,0.119744706,0.041909859,0.060597877,0.064960586,0.116000286,0.038220252,0.037904856,1.226956051,2.842572836,0.165649355,-0.6207332,1.737244682,0.123624969,0.257484856,-0.669374535,-0.419325534,-0.09920534 -662,F58V,0.028692807,0.074743462,0.040002758,0.113965939,-0.33502622,0.049219721,0.022135064,0.035250549,-0.210415734,0.068687797,0.080799126,0.086991193,-0.006985677,0.125852455,0.102079423,-0.208481253,-0.461571187,1.2415502,2.010648477,-2.256215257,-2.131777954,-3.728735435,-2.301872734,-1.128338425,-1.990351738,-2.05145733,0.607872927 -663,F58Y,-0.022005374,-0.004815293,-0.027550576,0.088073872,-0.020413011,0.106657252,-0.003327738,-0.04068301,-0.165576783,-0.095199728,0.085569142,0.006941694,-0.062042846,0.025818304,0.15032944,-0.073284113,0.032458091,1.219987286,2.328097342,2.810577368,1.907713646,3.848563171,3.197073761,2.733170494,2.366365768,1.631268395,1.278645988 -664,R59A,-0.042590036,-0.009806075,-0.014219912,-0.299772351,-1.945165273,0.02673729,-0.009590043,-0.075590029,-0.053517282,0.029697942,-0.049310091,-0.001746285,-0.026693538,-0.136592425,-0.462952277,-1.704582362,-2.185748184,1.099183575,1.346233123,-7.037316512,-6.472022644,-7.287424759,-7.158469475,-6.188660515,-8.080005165,-5.888180525,-3.128914344 -665,R59C,-0.024958554,0.004552714,-0.031984195,-1.026452236,-1.573662471,0.036745006,0.031450621,-0.081367729,-0.029718634,-0.015187495,0.024292922,-0.024518187,-0.039450202,-0.912916378,-1.139988094,-1.409979551,-1.73734539,3.225896783,2.657104414,-10.57249205,-9.747202705,-10.35273053,-11.24563578,-10.0832047,-11.43368652,-8.717475851,-6.657244455 -666,R59E,-0.061230755,0.070267371,-0.714981819,-1.75309971,-2.998283498,0.021716549,-0.04198176,-0.080479749,-0.049087261,0.041814639,0.098720103,-0.476394554,-0.953569083,-1.566438108,-1.939761311,-2.594980198,-3.401586797,1.782280772,0.914195358,-7.942248407,-7.840119385,-7.893029816,-8.707571236,-6.562027802,-8.708493797,-6.546616016,-3.047025845 -667,R59D,-0.065755847,-0.022956355,-1.238107865,-1.901520979,-3.24264753,0.074673979,-0.007084544,-0.124427149,0.054712038,-0.011067118,-0.034845591,-0.985872184,-1.490343545,-1.754935515,-2.048106443,-2.850424395,-3.634870665,2.38602495,1.117118587,-6.95260229,-6.777798676,-7.395041908,-7.378039436,-6.181769493,-7.030361938,-5.667329775,-1.897346082 -668,R59G,-0.100110431,0.001586835,0.005493659,-1.397291037,-2.30278815,0.045180953,-0.068039856,-0.132181005,-0.016586963,0.062921023,-0.059747353,0.033749461,-0.022762143,-1.102850864,-1.691731209,-2.388957256,-2.216619043,0.808445418,0.752590434,-6.733596417,-5.96677668,-6.864717995,-6.253848686,-6.356411858,-8.226226868,-6.005111808,-1.951926051 -669,R59F,0.02912799,0.131202627,-0.877001222,-1.75491193,-2.769432224,-0.048511577,0.08382446,-0.025568481,0.011266968,0.146474049,0.115931204,-0.560760894,-1.19324155,-1.486947645,-2.022876214,-2.339398476,-3.199465972,2.434101652,1.396393503,-11.94856035,-10.47429941,-10.67109741,-12.26678889,-11.40719805,-14.92341799,-8.32591348,-5.80072921 -670,R59I,-0.045435409,-0.378140778,-2.26922529,-2.365565035,-2.656506313,0.013935291,0.015190274,-0.106061092,-0.078521358,-0.239787244,-0.516494312,-1.944668281,-2.593782298,-1.967765046,-2.763365024,-2.218155885,-3.094856741,1.01928359,-0.083652297,-10.28759677,-10.10684538,-9.050570412,-10.64357145,-9.603315506,-12.03368109,-8.113570381,-5.564838884 -671,R59H,-0.090263181,0.027011045,0.028195907,0.022095261,-0.328139955,-0.003005839,-0.081965057,-0.098561305,-0.039351316,0.10062112,-0.04659903,0.042703646,0.013688167,0.08930238,-0.045111859,-0.248847958,-0.407431952,1.097282766,1.830180642,-3.829263004,-3.41548143,-4.517429092,-4.639884819,-3.240265793,-3.333253883,-4.469526615,-2.18938999 -672,R59K,-0.03219834,0.028808057,-0.000719808,0.013379948,-0.386167521,0.044967387,-0.040613244,-0.023783435,-0.028311875,0.06301945,-0.005403336,0.009656943,-0.011096559,0.081187001,-0.054427106,-0.198980229,-0.573354812,1.360713075,2.097047964,-4.541923332,-4.230873222,-5.203248756,-5.256186478,-3.178509247,-4.840798958,-4.122695745,-3.434496636 -673,R59M,-0.071399525,0.012237583,0.022352959,-1.47320788,-2.432379025,0.009369572,-0.054696873,-0.088102177,-0.108116188,0.041169225,-0.016694059,0.048996508,-0.00429059,-1.136915104,-1.809500655,-2.401546383,-2.463211667,0.841818673,0.751361793,-9.642452948,-9.49129718,-8.509604942,-10.53417606,-9.157949478,-10.51923708,-7.729045212,-5.192755711 -674,R59L,-0.093957323,0.006592326,-0.192024289,-1.676102509,-2.407907628,0.031967654,-0.062492401,-0.125422244,-0.02004301,0.022748811,-0.00956416,-0.170761431,-0.213287147,-1.355479948,-1.99672507,-2.297541553,-2.518273703,0.945328032,0.741805289,-8.117409747,-8.131699005,-6.509463226,-8.877495003,-7.523837547,-9.544553955,-6.735077498,-3.156569152 -675,R59N,-0.056316373,-0.038195076,-0.059163611,0.014539776,-0.080553187,-0.136352127,-0.102833907,-0.009798838,0.047171195,0.024503367,-0.100893518,-0.013119338,-0.105207884,0.077382708,-0.048303157,-0.035332573,-0.1257738,1.32522348,2.628793189,-3.864551964,-3.103199608,-4.401668861,-4.962664589,-3.575161964,-3.280064796,-4.054445912,-0.211320111 -676,R59Q,-0.047080892,0.023520317,-0.039072019,-0.020442319,-1.436483915,-0.00298896,-0.040496735,-0.053665048,-0.051685896,0.081803611,-0.034762978,0.025393114,-0.103537152,0.068204406,-0.109089044,-1.519645695,-1.353322134,0.498500683,1.308308003,-4.071791742,-3.662816978,-4.064066841,-5.050715446,-3.630952034,-3.95040741,-4.851268627,-2.478353831 -677,R59P,-0.061596319,-1.395127806,-1.941935654,-2.091503064,-2.681074897,0.041340868,-0.009504704,-0.113687933,-0.045990764,-1.473633998,-1.316621614,-1.827511065,-2.056360242,-1.850607829,-2.332398299,-2.288085312,-3.074064481,4.010222422,1.747709752,-11.27909548,-11.28242883,-10.96008427,-11.27062286,-10.4635381,-12.41880336,-9.645061972,-7.829719483 -678,R59S,-0.054163726,0.045891017,0.00872414,-0.861572468,-1.875296865,0.055914519,0.005905607,-0.114233058,0.001117281,0.062126962,0.029655072,0.011229832,0.006218447,-0.427616499,-1.295528437,-1.67945258,-2.071141149,1.683014004,1.462562609,-7.780252371,-6.933135742,-7.733169357,-8.083130119,-7.159741951,-8.992084686,-6.585104841,-3.62608655 -679,R59T,-0.072327592,0.01533939,-1.003471343,-1.726944719,-2.823482028,0.040687882,-0.035459925,-0.109195259,0.028848927,0.045815144,-0.015136364,-0.73525841,-1.271684275,-1.528819596,-1.925069841,-2.455904046,-3.191060009,2.446128567,1.32204429,-9.443088037,-8.619338348,-9.50073307,-9.583378754,-8.829517807,-10.68247221,-7.722745159,-5.238081264 -680,R59W,-0.085113947,0.040481937,-0.018723159,-1.581441636,-2.399050209,0.025024459,-0.039688396,-0.130539497,-0.018110882,0.047032953,0.03393092,0.021516305,-0.058962623,-1.208518716,-1.954364555,-2.185908284,-2.612192134,0.99703554,0.748977568,-11.38903369,-10.98464271,-10.29495852,-11.90124191,-11.53694681,-12.22737849,-10.12454405,-9.510327637 -681,R59V,-0.069056612,-0.188942887,-1.504193137,-2.21401196,-3.269411588,0.045472478,-0.034711105,-0.103402119,-0.023226306,-0.075407186,-0.302478587,-1.430694301,-1.577691972,-1.816968968,-2.611054951,-2.482333156,-4.05649002,3.066680349,1.51886324,-9.619794949,-9.611879555,-8.808767952,-9.909516258,-9.243965263,-10.52484572,-7.807601627,-5.104722384 -682,R59Y,0.005267378,0.071039837,0.029843654,-1.214850331,-2.747228401,0.041797537,0.073808992,-0.063274236,-0.085264244,0.135032701,0.007046973,0.03236036,0.027326948,-0.815786524,-1.613914137,-2.344930965,-3.149525837,1.778872614,1.282296824,-10.03936373,-8.617595482,-10.6292198,-10.61092747,-9.522049583,-10.81702634,-7.641100389,-4.221834521 -683,P60A,-0.04836535,-0.004979135,-0.000603067,0.007613094,-0.003690421,0.041708014,-0.065009165,-0.031721534,-0.017038232,0.011214907,-0.021173176,0.010812166,-0.0120183,0.035312657,-0.020086469,0.071862168,-0.07924301,1.030512501,2.682596954,1.789740173,1.369526855,2.176213158,1.716294601,1.709180725,1.977485527,-1.009612059,1.637411201 -684,P60C,-0.034201341,0.038522013,0.003333269,0.0216651,-1.87440672,-0.00835588,-0.044536718,-0.023865963,-0.037053369,0.011214907,0.065829119,-0.008395947,0.015062485,0.070314606,-0.026984406,-1.344410815,-2.404402624,0.569084163,1.321609415,-4.29919409,-4.156973854,-4.128149956,-3.885563873,-4.888862717,-4.436420052,-5.30835441,-3.504702734 -685,P60E,0.015935289,0.039689396,-0.034909809,0.012443624,0.019215497,0.036139465,-0.016134585,0.048005163,-0.042570246,-0.01863624,0.098015032,-0.088599547,0.018779929,-0.055802678,0.080689926,-0.023370068,0.061801062,1.4671573,2.665763981,-0.271823232,-0.211594536,-0.165288101,-0.846256012,-0.613860611,0.477883102,-2.000330576,0.387588171 -686,P60D,-0.014733166,0.021542427,0.031799341,0.029683141,0.010643743,0.003779805,-0.041429846,0.011963514,0.005622136,-0.009202998,0.052287851,0.058786125,0.004812557,0.037711286,0.021654995,0.07983167,-0.058544185,1.126870742,2.84560063,-2.587293001,-3.100463181,-3.72216806,-1.98108992,-2.378792389,-1.753951454,-2.795441515,-0.616524957 -687,P60G,0.030995074,0.013120405,-0.019277883,0.007261521,-0.021573991,0.006501684,0.023868785,0.038121363,-0.012809228,-0.030938237,0.057179047,-0.027083508,-0.011472257,0.01345049,0.001072552,0.026024807,-0.069172788,1.200850847,2.707344788,-0.143434258,0.203509369,0.310370193,0.100966942,-1.129022812,-0.20299498,-1.662660878,1.159768042 -688,P60F,0.001822431,0.060632872,0.007436027,0.037889361,-1.310573596,0.039709044,0.038301003,-0.034656141,-0.014069165,0.058447822,0.062817922,-0.019478157,0.03435021,0.118753159,-0.042974437,-0.779224275,-1.841922916,0.571954305,1.360663368,-5.310452931,-5.626729156,-5.701757072,-4.841486572,-5.538373901,-4.843917953,-6.062264824,-4.868615669 -689,P60I,-0.031402446,0.099016312,0.040388106,0.054243486,-0.070069557,0.033991912,-0.056106086,-0.006698806,0.035502249,0.125177294,0.07285533,0.100981679,-0.020205467,0.137706597,-0.029219625,-0.001932919,-0.138206195,1.239676548,2.841142242,-3.382186952,-3.913380425,-3.049807556,-3.53350573,-3.864397743,-2.549843308,-3.980877027,-2.782131049 -690,P60H,-0.016951481,0.018089997,-0.041510258,0.015211658,-0.000633666,-0.011591336,-0.041118969,0.007216007,0.031508895,0.042277665,-0.006097671,-0.040020199,-0.043000316,0.014797278,0.015626038,0.054070314,-0.055337645,1.057823004,2.69928244,-3.6799621,-3.299964127,-4.751987274,-2.550566704,-3.643813324,-4.153479073,-4.607733465,-2.595425396 -691,P60K,-0.006089837,0.016451137,0.018501809,0.008513421,-0.067379763,0.002635555,-0.009142359,-0.003037314,-0.051005004,0.000284639,0.032617634,0.002524404,0.034479214,-0.019979259,0.037006101,-0.053019656,-0.08173987,1.285926774,2.394443934,-2.993314661,-2.206793167,-4.139293747,-2.646391197,-2.745931343,-3.228163849,-3.961418155,-2.587132114 -692,P60M,-0.003974583,0.01357206,-0.002607613,0.009209514,0.028805142,0.033636914,0.014758188,-0.022707353,0.020097745,0.039704421,-0.012560302,0.014417436,-0.019632661,0.035982585,-0.017563557,0.058320891,-0.000710608,1.190057792,2.955570893,-2.478572084,-2.912114456,-2.260661957,-2.873435738,-2.851833641,-1.494814629,-3.199615463,-2.7724602 -693,P60L,-0.056402031,0.025734487,0.012765024,0.0322581,-0.201132372,0.048973072,-0.052737809,-0.060066252,-0.010035957,0.035622489,0.015846485,0.041874241,-0.016344193,0.061359763,0.003156436,-0.119164733,-0.28310001,1.717760377,2.670996696,-2.167043233,-3.16683934,-1.87036837,-2.27328727,-2.706175064,-0.81854612,-2.554108236,-1.914438436 -694,P60N,-0.011285649,0.072278646,0.007683625,0.038777988,-0.283547776,0.091404771,0.020589591,-0.043160888,0.030951296,0.057381206,0.087176085,0.031959659,-0.016592409,0.031261979,0.046293996,-0.196629518,-0.370466033,1.25985554,1.996258778,-3.74771433,-3.560419556,-5.002845993,-3.172810699,-3.127396919,-3.87509848,-5.099484312,-0.862201855 -695,P60Q,-0.008239493,0.033192221,-0.057621955,0.010573048,0.01093068,0.007899242,-0.056633901,0.040154916,-0.01544058,0.057152512,0.009231929,-0.08041295,-0.03483096,0.063178912,-0.042032816,0.055105582,-0.033244223,1.171090344,2.942343097,-0.941399001,-0.594023674,-1.73176886,-0.870970497,-1.632305054,0.122073082,-2.177287562,-0.994877648 -696,P60S,-0.009322237,0.043124534,-0.001805577,0.034161437,0.030974114,0.013435455,-0.015123231,-0.003521242,0.004597453,0.036610737,0.049638331,0.005077444,-0.008688597,0.027970655,0.040352219,0.061101339,0.000846888,1.110969013,2.691206778,0.587536212,0.369533707,0.097412651,1.482212204,0.19282962,0.795692879,-0.794452721,-0.24295268 -697,P60R,-0.004414994,0.043772202,0.019712724,0.040300622,-0.032174445,0.045328601,-0.014805849,0.005975861,-0.005643515,0.06111149,0.026432913,0.027684787,0.01174066,0.067820087,0.012781157,0.004652069,-0.069000959,1.143965006,2.71127695,-2.827401413,-2.994508087,-3.142144241,-1.988288277,-2.88616021,-3.12590625,-4.152948941,-2.761088304 -698,P60T,0.000818803,0.022614209,-0.009437638,0.02905448,-0.035869273,0.018944151,-0.015293381,0.016930986,0.004355085,0.011060752,0.034167666,-0.032543914,0.013668639,0.024179832,0.033929127,-0.037107723,-0.034630822,1.374862648,2.587037061,-2.314295662,-2.828869087,-2.322224701,-1.680622963,-3.088640419,-1.65112114,-3.883220073,-2.715107843 -699,P60W,-0.059501254,0.015172076,-0.030994184,0.03910482,-1.297597785,0.036699766,-0.040822016,-0.078180491,-0.032926463,0.004245137,0.026099014,-0.006697164,-0.055291203,0.059817551,0.018392088,-1.043970493,-1.551225076,0.726531226,1.354970832,-5.519948232,-5.533830574,-5.699464058,-4.882254105,-5.815959023,-5.668233398,-5.995415764,-4.868615731 -700,P60V,-0.046430783,0.017781199,-0.030849562,0.001336067,-0.08649214,0.067162908,-0.029458435,-0.063403131,0.004303478,0.068992335,-0.033429937,-0.037817517,-0.023881607,0.014797278,-0.012125145,-0.061187929,-0.111796351,1.356216533,2.503366217,-2.354817043,-3.09641169,-2.29846093,-2.43045639,-2.203055725,-1.745700478,-3.248838696,-1.97232178 -701,P60Y,-0.063063027,-0.001563967,-0.017699366,-0.003928153,-0.807193813,0.007670017,-0.078637273,-0.047488781,0.036197531,-0.035695104,0.032567171,0.0000256,-0.035424332,-0.003336287,-0.004520019,-0.550246316,-1.064141309,0.896020182,1.48144071,-6.418426399,-5.974140945,-7.307632401,-5.634822571,-6.374250725,-6.801285355,-6.515645319,-5.522262105 -702,E61A,0.063557894,-0.018393502,0.018657924,0.037613292,-0.012261803,0.086352349,0.044354946,0.082760841,0.004278394,-0.071001751,0.034214747,0.000537546,0.036778302,0.001721021,0.073505563,-0.053306104,0.028782499,1.350789303,2.49975486,-2.155384154,-2.025552635,-1.828559715,-1.945266342,-2.570736351,-2.406805725,-2.625736819,-1.130478774 -703,E61C,0.001840954,0.056106345,0.02455509,-0.020366857,-1.223368361,0.0943779,0.003284038,0.00039787,-0.009460814,0.055272389,0.0569403,0.076871164,-0.027760984,-0.026528789,-0.014204925,-0.711768721,-1.734968,0.82049415,1.421275426,-5.447578735,-4.947538849,-5.048990402,-5.853816643,-5.672109261,-5.715438522,-6.429881345,-4.394549692 -704,E61D,0.024411174,-0.022018895,0.016038806,0.01835173,0.017772369,0.040897143,-0.024871084,0.073693432,-0.008597704,-0.009966595,-0.034071194,0.044393927,-0.012316315,-0.00871353,0.045416989,0.007855136,0.027689601,1.198306228,2.640054888,1.644449168,2.559943527,1.586135246,1.970231636,0.612622925,1.493312508,0.778377199,1.885214551 -705,E61G,-0.013910738,-0.048552622,-0.039335574,-0.005067915,0.008092791,0.079627469,-0.020897202,-0.006924273,-0.047917821,-0.039719612,-0.057385631,-0.025087297,-0.053583851,-0.015957771,0.005821941,-0.010719298,0.02690488,1.291626607,2.628278631,-1.552451277,-1.431258797,-1.409923874,-1.318636498,-1.676094376,-1.926342842,-2.551537615,-0.241011161 -706,E61F,0.084022179,-0.000466742,-0.003419893,0.093356546,0.036097239,0.00847417,0.072232424,0.095811934,-0.032435712,0.025197822,-0.026131305,0.068773018,-0.075612803,0.057440812,0.12927228,0.008939763,0.063254715,1.149911372,2.605954966,-5.242485426,-3.795200417,-4.90162825,-6.068611008,-5.493646408,-5.953341049,-5.650905524,-3.552738117 -707,E61I,0.099318972,-0.018766218,0.025746305,0.03817622,-0.168170948,0.06833893,0.076455024,0.12218292,-0.0000738,-0.065632374,0.028099939,-0.051762008,0.103254617,-0.00844311,0.08479555,-0.201510918,-0.134830978,1.354111417,2.066307219,-6.080721149,-5.451577278,-5.599807236,-6.590404045,-6.123397636,-6.638419548,-6.903640192,-5.039763884 -708,E61H,0.011416504,-0.007498247,0.032310451,0.034168159,0.018249952,-0.004774258,-0.049567524,0.072400531,0.035408597,-0.014565388,-0.000431105,0.062676679,0.001944223,0.022458298,0.045878019,0.029438054,0.007061849,1.201053283,2.641557674,-1.794834117,-1.553714561,-1.822637749,-1.845169746,-2.016146286,-1.736502243,-3.218394821,-0.83107925 -709,E61K,0.081382181,0.026833051,0.118560038,0.084336492,0.051632487,0.171953313,0.039165221,0.12359914,-0.147276252,-0.024622475,0.078288577,0.096556113,0.140563962,0.013166086,0.155506897,0.010235895,0.093029078,1.283217775,2.834887473,-1.713748334,-1.465958992,-1.551543823,-2.160256767,-1.858978653,-1.532003433,-3.653917828,-1.028792049 -710,E61M,0.054394781,0.033971043,0.056696705,0.078574935,0.04607429,0.067850629,0.014282757,0.094506804,-0.039827427,0.003202834,0.064739252,0.06420862,0.049184789,0.002073009,0.15507686,-0.012388618,0.104537198,1.136074331,2.469853608,-4.543099944,-4.168432411,-4.044610229,-5.436769531,-4.38429036,-4.681397186,-5.331708554,-3.182739017 -711,E61L,0.022090156,-0.047770883,-0.024585716,0.02011436,-0.043914108,0.011503476,-0.010121701,0.054302013,-0.041403239,-0.054929402,-0.040612363,-0.014842443,-0.034328989,-0.011171658,0.051400378,-0.064323226,-0.02350499,1.270198658,2.429479188,-4.368369296,-4.024441605,-3.883306656,-5.070032166,-4.185668633,-4.678397423,-5.068428063,-2.932747478 -712,E61N,0.029927954,-0.014141241,0.011966719,-0.011644097,-0.0169525,0.05637949,0.018082728,0.041773179,-0.03285874,-0.033314,0.005031518,0.035436877,-0.011503439,-0.055003027,0.031714834,-0.055784202,0.021879202,1.187372712,2.582314897,-0.082960959,0.444704124,0.044830711,-0.588744865,-0.199732574,-0.11586219,-2.380832413,0.264784808 -713,E61Q,0.073308264,0.082165601,0.050951592,0.04309535,0.030477973,0.026678434,0.005104982,0.141511545,-0.020087996,0.06995767,0.094373531,0.097525016,0.004378167,-0.000484179,0.086674879,0.076066901,-0.015110955,1.060067016,2.791847385,-1.365918852,-1.696627426,-1.273530891,-1.517893257,-1.17379464,-1.167748047,-2.771733215,-1.062769415 -714,E61P,0.010494823,-0.975078858,-1.892559423,-2.220149339,-2.8231702,0.09721601,0.01114723,0.009842416,-0.030467012,-0.894647218,-1.055510497,-1.970668669,-1.814450177,-2.209966549,-2.230332128,-2.731179734,-2.915160666,1.824619222,-0.024242249,-5.452435193,-4.917523911,-5.032420387,-5.772874954,-5.875061317,-5.664295395,-6.431826537,-4.26893643 -715,E61S,0.059884694,-0.02494304,0.010314503,0.035750894,0.012718307,0.073109024,0.027170126,0.092599262,-0.04275198,-0.041325152,-0.008560927,-0.009342175,0.02997118,-0.002662176,0.074163964,-0.01445115,0.039887764,1.355524107,2.693486272,-1.84757691,-1.656852486,-1.44380172,-2.251457459,-2.195382652,-1.690390236,-3.649193504,-0.722235318 -716,E61R,0.012236341,-0.031955028,0.007580619,-0.000541371,-0.029997036,0.09699304,-0.020821655,0.045294336,-0.031057831,-0.036625469,-0.027284586,0.016303469,-0.001142231,-0.027965607,0.026882865,-0.034520376,-0.025473695,1.334904031,2.534968346,-2.389532899,-2.758966515,-2.327954803,-2.481797539,-2.427677086,-1.951268555,-4.654248852,-1.340625529 -717,E61T,0.042707501,-0.040018981,0.03847835,0.016013805,-0.035050369,0.047572163,0.009279288,0.076135713,0.031730237,-0.046559784,-0.033478177,0.048763744,0.028192955,0.006071656,0.025955953,-0.008942462,-0.061158275,1.155729208,2.502711711,-1.965605602,-1.82394857,-1.711977783,-2.292309151,-2.480125191,-1.519667313,-3.488624273,-0.872233789 -718,E61W,0.012509989,-0.093801157,-0.002535813,-0.017620335,-0.017401177,0.034984328,-0.028692844,0.053712821,-0.062628952,-0.084668849,-0.102933465,-0.013049321,0.007977695,-0.015289883,-0.019950786,-0.054834184,0.020031831,1.411089207,2.462063717,-6.967881641,-6.166737312,-6.312917213,-7.617168861,-7.642348541,-7.100236275,-7.806903161,-6.904467192 -719,E61V,0.032545471,0.016172889,0.0589945,0.044248441,-0.074498357,0.022989293,0.010752814,0.054338128,-0.136064325,-0.014152067,0.046497844,0.053363543,0.064625457,0.001853723,0.086643158,-0.08880883,-0.060187884,1.264080769,2.326350792,-5.634791203,-5.15283857,-5.264693123,-5.924326218,-5.959013023,-5.873085083,-6.150970889,-4.707986016 -720,E61Y,0.027267022,0.014843124,-0.027411743,0.044179771,0.021190484,0.043230267,-0.004781514,0.059315558,-0.075663517,-0.015222871,0.044909119,-0.025148255,-0.02967523,0.028056064,0.060303478,0.04400175,-0.001620782,1.107575506,2.761382807,-4.332429865,-2.982725098,-4.339877983,-5.115777168,-4.452688866,-4.771080208,-5.041387493,-2.734739141 -721,E62A,0.057473014,-0.068437308,-0.022054588,-0.058308636,-1.023939685,-0.037792471,0.069092883,0.045853144,-0.157236776,-0.14233916,0.005464545,-0.071693893,0.027584717,-0.130848237,0.014230966,-0.729163351,-1.318716018,1.994314641,2.054932464,-3.999530995,-4.134581055,-4.044426689,-4.383674133,-3.695254097,-3.739719002,-3.437114613,-2.462619106 -722,E62C,0.042274149,-0.121437569,-0.013264833,-0.086399352,-1.82322916,0.028063802,0.124176147,-0.03962785,-0.211192888,-0.192043326,-0.050831812,-0.058664733,0.032135067,-0.05605222,-0.116746483,-1.640053308,-2.006405012,0.854978339,1.321813471,-8.316265564,-8.264859337,-7.479309586,-8.964481827,-7.815267036,-9.057410034,-6.925598376,-5.295657948 -723,E62D,-0.007403706,-0.117832134,-0.024481754,-0.052771188,-0.100650825,-0.007976516,0.026175254,-0.040982666,-0.180752767,-0.20057545,-0.035088817,-0.062290609,0.013327101,-0.049543105,-0.05599927,-0.157552444,-0.043749205,1.486383896,2.224128984,-3.166267741,-2.403731842,-2.341426514,-3.362663338,-3.27143309,-4.452083923,-3.358354545,-1.975962715 -724,E62G,0.033345852,-0.045591752,0.012688699,-0.028065379,-1.366168672,0.005711112,0.065714434,0.00097727,-0.162906779,-0.101420483,0.010236979,-0.005008394,0.030385792,-0.029115452,-0.027015305,-1.338544487,-1.393792856,0.773145656,1.337382617,-6.219946793,-6.282016579,-5.351800102,-6.742992516,-5.54053418,-7.182390587,-5.161135983,-3.732310641 -725,E62F,0.062333305,-0.116990796,-0.082009373,-0.02231879,-1.220230028,-0.013219301,0.08284925,0.041817359,-0.071007853,-0.257102409,0.023120817,-0.160440777,-0.003577968,-0.080991779,0.036354199,-1.26524793,-1.175212126,1.116169412,1.394104454,-9.539380431,-8.887344673,-7.651852402,-11.09285929,-9.257720345,-10.80712544,-6.561811819,-4.66466524 -726,E62I,0.046353487,-0.055628559,-0.056898239,-0.04850649,-1.344574689,0.014523478,0.086647876,0.006059098,-0.175803728,-0.141360965,0.030103847,-0.007114375,-0.106682102,-0.051669558,-0.045343422,-1.408118307,-1.28103107,0.727198626,1.328669588,-7.938311865,-7.532942139,-6.996696228,-8.625377518,-7.641829132,-8.89471431,-6.278602787,-3.805324489 -727,E62H,0.010724482,-0.119281208,-0.019642727,-0.090061275,-0.66028634,-0.014945307,0.039477632,-0.018028668,-0.158842946,-0.14329443,-0.095267985,-0.074136261,0.034850807,-0.102781443,-0.077341106,-0.541009166,-0.779563514,1.340589675,1.697964927,-6.519878671,-6.082076859,-5.366415161,-7.73332782,-6.16233194,-7.255241577,-5.295167067,-3.477391585 -728,E62K,-0.028776684,-0.089657145,-0.057783908,-0.129572348,-1.893940849,0.004829364,-0.017884629,-0.039668739,-0.274654342,-0.15449398,-0.024820309,-0.08460281,-0.030965005,-0.10374907,-0.155395625,-1.789459054,-1.998422644,0.843555078,1.313262086,-5.359823912,-4.739071152,-4.511423386,-7.060913612,-4.718440773,-5.769270638,-4.580831734,-2.116349898 -729,E62M,0.099765744,-0.035625318,0.011909786,-0.032663627,-0.358510262,-0.05332559,0.108766772,0.090764716,-0.202313716,-0.100680206,0.029429571,-0.07809058,0.101910151,-0.015816112,-0.049511141,-0.350933536,-0.366086988,1.447161352,1.93901136,-6.816425671,-6.09575074,-6.248292702,-8.155899849,-6.676098251,-6.906086815,-5.314935974,-3.609943238 -730,E62L,-0.006835099,-0.069357455,-0.053868758,-0.062592013,-1.942943043,-0.003179359,0.020497501,-0.034167698,-0.194971851,-0.108602054,-0.030112856,-0.081288762,-0.026448754,-0.04000742,-0.085176605,-1.475839931,-2.410046154,0.94388828,1.343679321,-6.984019052,-6.235318878,-6.272127258,-8.018081383,-6.850154854,-7.544412888,-5.086746169,-2.988049167 -731,E62N,0.003220923,-0.072703974,-0.043164174,-0.07238916,-1.491877677,0.005444591,-0.002186603,0.008628448,-0.095499586,-0.170502767,0.02509482,-0.087471995,0.001143648,-0.056698973,-0.088079346,-1.104165272,-1.879590082,0.624383502,1.340195457,-6.212770065,-5.601658859,-5.467866455,-7.326501541,-5.756139107,-6.911684364,-5.756159806,-3.832298895 -732,E62Q,0.061097446,-0.069194688,-0.007620568,-0.045751279,-0.310831814,-0.087726809,0.050104307,0.072090584,-0.051009758,-0.104457692,-0.033931683,-0.086116235,0.070875099,-0.113353654,0.021851097,-0.33497267,-0.286690958,1.771994887,2.212711317,-2.953250681,-2.28539772,-2.777685242,-4.14643222,-2.495393387,-3.061344833,-2.943035715,-1.970683841 -733,E62P,-0.016243763,-1.479490774,-2.007118191,-2.343557308,-2.796100017,0.002751608,-0.000136789,-0.032350737,-0.219519247,-1.665769511,-1.293212036,-2.123013794,-1.891222588,-2.267052394,-2.420062221,-2.695396884,-2.89680315,0.082204336,-1.116553491,-9.228824875,-9.313409309,-8.538037819,-9.673707855,-8.714990112,-9.903979279,-8.069129252,-6.519158986 -734,E62S,0.012566713,-0.039193313,-0.005399597,-0.049149026,-0.991022422,-0.040509579,0.00982489,0.015308536,-0.157198668,-0.067493949,-0.010892677,-0.050283172,0.039483978,-0.060382625,-0.037915427,-0.670589813,-1.31145503,0.894347698,1.448742021,-4.583587503,-4.799233322,-4.467634033,-5.481898811,-3.932023071,-4.237148277,-4.777297667,-3.114443917 -735,E62R,0.036320027,-0.043425958,0.000866879,-0.070105213,-2.055450033,0.02293856,0.053948541,0.018691513,-0.155366809,-0.121426684,0.034574769,-0.066141495,0.067875252,-0.052963783,-0.087246642,-1.706656646,-2.404243419,0.918369718,1.323135725,-4.651877994,-3.88831498,-3.779259232,-5.8433144,-4.666684685,-5.081816673,-4.171810855,-1.739471885 -736,E62T,-0.012736448,-0.087258738,-0.087441348,-0.084723466,-0.291571286,-0.060228041,-0.027513164,0.002040268,-0.176732663,-0.11171819,-0.062799286,-0.128939876,-0.04594282,-0.093840781,-0.075606151,-0.26823922,-0.314903352,1.542292374,2.081401642,-4.581104628,-4.593128265,-4.220194962,-5.073418633,-4.212344231,-4.80643705,-5.127582269,-2.045240493 -737,E62W,0.086498837,-0.06090279,-0.038870471,-0.012690395,-1.931454624,-0.075435128,0.091618831,0.081378843,-0.148610688,-0.184164651,0.062359072,-0.128783823,0.051042881,-0.046804825,0.021424036,-1.664584339,-2.198324909,0.687852216,1.31160748,-10.49994027,-9.773269691,-8.897498947,-11.9273213,-10.23526061,-11.66635082,-8.574534898,-7.384837031 -738,E62V,-0.001870541,-0.121185084,-0.017289387,-0.043605708,-0.936311053,0.012342856,0.023304282,-0.027045363,-0.18686835,-0.164644898,-0.07772527,-0.065912849,0.031334075,-0.028124288,-0.059087128,-0.643599848,-1.229022258,1.528433409,1.780285502,-6.587497131,-5.939729424,-5.596568085,-7.141776443,-6.719195366,-7.540216339,-5.222336449,-2.593434768 -739,E62Y,-0.008455438,-0.070276425,0.046305106,-0.059928347,-1.2178737,-0.003224918,-0.006609425,-0.01030145,-0.160316776,-0.122894994,-0.017657855,-0.001258893,0.093869104,-0.08396715,-0.035889543,-0.965614335,-1.470133064,1.046699293,1.428955096,-9.857638837,-9.821087486,-7.830883881,-11.13826691,-9.066796356,-11.43115955,-6.787782095,-4.94285288 -740,R63A,-0.053937372,0.02686806,-0.027505855,-0.027537789,-1.552993834,0.02522155,-0.034855688,-0.073019055,-0.05945277,0.024921336,0.028814784,-0.036995679,-0.018016031,-0.011864608,-0.043210969,-1.204657826,-1.901329841,0.783630527,1.347390092,-6.139308664,-5.8964319,-6.442352402,-6.174938599,-6.831125572,-5.351694847,-4.181020259,-2.463916723 -741,R63C,0.003778682,0.052228344,0.039806486,-0.110801758,-1.577282491,0.012800858,0.006399609,0.001157754,0.061034622,0.009931759,0.094524929,0.048658555,0.030954417,-0.092447451,-0.129156064,-1.581911065,-1.572653916,1.024111184,1.343607555,-8.949303322,-9.903201141,-8.712929184,-8.521634323,-9.315056709,-8.293695251,-7.146964873,-5.792937447 -742,R63E,-0.049669841,0.023391586,-0.042143479,-0.036506677,-1.482423194,0.025941044,-0.019756125,-0.079583556,0.02516146,0.003865467,0.042917705,-0.07774742,-0.006539538,0.00172408,-0.074737433,-1.645081357,-1.319765031,0.732320386,1.316981787,-10.41243823,-12.67499421,-9.299268188,-10.58946328,-10.19460715,-9.303858307,-6.100753338,-2.863424772 -743,R63D,-0.093154388,0.00822422,-0.169084097,-1.836651517,-2.506009658,0.057251346,-0.016668201,-0.169640574,-0.049309202,0.001611686,0.014836754,-0.133280718,-0.204887475,-1.497424246,-2.175878787,-2.281757547,-2.730261769,1.168358658,0.757981958,-11.29103313,-12.77301491,-12.5106276,-11.18095947,-9.7030355,-10.28752816,-7.379504973,-4.374417863 -744,R63G,-0.064787167,0.020064104,-0.015426586,-1.322110985,-2.512185941,0.005717024,-0.034450614,-0.09512372,-0.007465448,0.027696412,0.012431796,-0.03010389,-0.000749281,-0.834621542,-1.809600427,-2.244839517,-2.779532364,1.83777074,1.33816789,-9.22614644,-9.844372314,-8.594358459,-9.663007393,-9.636149811,-8.392844223,-6.518095446,-4.513749946 -745,R63F,-0.069008369,0.029277964,-0.086500672,-0.074559971,-1.828182638,-0.061251133,-0.081522341,-0.056494396,0.023797897,-0.032071427,0.090627355,-0.04345605,-0.129545294,0.028628318,-0.177748259,-1.412350673,-2.244014602,0.60156222,1.319371867,-8.530368129,-8.331327965,-8.043347099,-9.508874413,-9.067476822,-7.700814346,-6.754426158,-4.699963656 -746,R63I,-0.053876189,-0.001550838,0.045928416,-0.065170486,-1.001374095,0.060208595,0.018931754,-0.126684131,-0.023974885,0.064929465,-0.06803114,0.075752914,0.016103917,0.030027554,-0.160368525,-0.534333003,-1.468415186,0.716476379,1.43715286,-9.291897765,-10.21273226,-9.04242157,-9.14089209,-8.187891953,-9.875550949,-6.595232809,-2.50538904 -747,R63H,-0.063345388,-0.009265087,-0.031860968,-0.054240048,-0.532573946,0.037572934,-0.030349153,-0.096341622,0.081465138,0.005718604,-0.024248778,-0.031477879,-0.032244057,-0.035958123,-0.072521973,-0.421945722,-0.643202169,1.408944399,1.867423219,-5.947789211,-7.30736013,-5.539088516,-5.753142616,-5.889709274,-5.249645515,-5.07289508,-2.552002267 -748,R63K,-0.060374056,0.035512884,-0.009030466,-0.038527773,-0.162804455,0.056068326,-0.046524829,-0.074223283,-0.032222669,0.046654566,0.024371201,0.013749305,-0.031810236,0.005073814,-0.08212936,-0.146046799,-0.179562111,1.430093859,2.296490931,-7.332225139,-7.598518326,-6.723132065,-7.632073029,-7.302365341,-7.405036934,-5.874237096,-2.447747845 -749,R63M,-0.051347407,0.068066699,-0.007027078,-0.058392767,-1.270809434,0.010663632,-0.057121157,-0.045573656,0.083235085,0.083851901,0.052281496,-0.023821027,0.009766871,-0.008987105,-0.107798429,-1.144038186,-1.397580682,0.688106978,1.341730603,-7.421247154,-8.512249268,-7.612768242,-7.479885887,-7.442247238,-6.059085136,-6.274256023,-4.082656486 -750,R63L,0.011221663,0.038670758,-0.014093258,-0.010820682,-0.418237842,-0.010758204,0.005697707,0.016745619,0.024830702,0.036347288,0.040994227,-0.022672989,-0.005513526,0.009836859,-0.031478223,-0.306941532,-0.529534151,1.130292289,1.752828686,-4.497442244,-4.641254288,-4.218142548,-4.890832207,-5.012228592,-3.724753586,-5.243967068,-1.942311951 -751,R63N,-0.080355608,-0.017129643,0.040729468,0.05179803,-1.582375994,-0.07005795,-0.090942465,-0.069768751,0.019867603,0.028224475,-0.06248376,0.049132589,0.032326346,0.120724249,-0.017128189,-1.412350673,-1.752401314,0.448112726,1.31190732,-10.24764977,-11.55348384,-9.331865898,-10.17172666,-10.03741586,-10.14375659,-7.327211148,-4.085044528 -752,R63Q,-0.032623525,0.05981111,-0.050418462,-0.015736444,-0.693159062,0.003327024,-0.025634574,-0.039612476,0.0000375,0.071846111,0.047776109,0.015289467,-0.11612639,0.008694059,-0.040166946,-0.514601681,-0.871716443,0.858296511,1.484045655,-7.800900121,-9.20846595,-7.387675354,-7.315996254,-7.508277206,-7.584085838,-5.791352037,-2.788628912 -753,R63P,-0.028605882,0.003872278,-0.016073859,-0.023242573,-1.086821958,-0.002744034,-0.018305773,-0.03890599,0.002451501,-0.008168219,0.015912774,-0.009977855,-0.022169863,-0.013150964,-0.033334181,-0.806714335,-1.36692958,0.80918625,1.395967489,-6.22511566,-6.010014694,-5.748600685,-6.272649055,-7.102545952,-5.991767914,-5.600562558,-1.308622927 -754,R63S,-0.062831038,0.010383432,-0.032349658,-0.053699102,-1.296136203,0.021958796,-0.056132727,-0.069529348,0.051454634,0.012871824,0.00789504,-0.041153503,-0.023545812,-0.030677641,-0.076720563,-1.02094819,-1.571324216,0.992518998,1.399458909,-6.408948653,-7.492794678,-6.446434525,-6.292117966,-6.166379303,-5.647016792,-5.462545058,-2.421000261 -755,R63T,0.002459675,0.059841811,0.023692966,0.007443551,-0.626124444,0.000400691,0.019389115,-0.014469766,-0.015746644,0.069161907,0.050521714,0.031447134,0.015938797,0.023284214,-0.008397112,-0.46905748,-0.783191408,0.821384722,1.490724102,-6.676408226,-7.77584819,-6.719531998,-6.392919113,-7.045464691,-5.448277138,-5.122309315,-2.71962727 -756,R63W,-0.075959751,-0.03415708,0.008220798,-1.042068925,-2.318079555,-0.021050899,-0.066800785,-0.085118717,0.097584111,-0.038597643,-0.029716517,-0.001299112,0.017740707,-0.548690149,-1.5354477,-1.926539668,-2.709619441,1.778474736,1.413689428,-9.062352611,-9.407581352,-8.898942513,-9.466279839,-9.502400795,-8.036558556,-7.738876758,-5.288188634 -757,R63V,-0.001262943,0.03592568,0.00911717,-0.023027042,-1.337554196,-0.001112964,0.037181537,-0.039707422,-0.007937357,0.009470619,0.062380741,-0.026630767,0.044865106,-0.028372612,-0.017681471,-1.091425848,-1.583682543,0.818372951,1.363491638,-8.13818463,-8.896631371,-8.290886726,-8.102747215,-7.690393753,-7.710264084,-5.672094503,-1.936902207 -758,R63Y,-0.035078013,0.073713263,0.022152567,0.013112338,-1.305136837,-0.021424274,-0.040634627,-0.029521398,-0.055383349,0.075605498,0.071821028,0.059356294,-0.01505116,0.100362469,-0.074137794,-0.933605885,-1.676667789,0.462292544,1.334906535,-8.670783517,-10.26926845,-8.456500748,-9.059950462,-8.572810555,-6.995387375,-6.1590945,-4.424966096 -759,F64A,0.013724989,-0.400159478,-1.616543688,-2.089278195,-3.388809431,0.055516183,0.022542618,0.004907359,,-0.365233708,-0.435085248,-1.673063391,-1.560023984,-2.144371588,-2.034184802,-2.801162415,-3.976456446,2.67816244,0.928730073,-10.31397514,-8.348962143,-10.07585074,-11.10702494,-11.24063365,-10.79740421,-6.627142216,-4.86424536 -760,F64C,-0.000465079,-0.101256261,-1.400783323,-2.83977023,-3.444423186,0.065283083,0.049790482,-0.050720639,,-0.053183325,-0.149329197,-1.288717434,-1.512849212,-2.189924656,-3.489615803,-3.119716756,-3.769129616,0.910740673,0.099954217,-12.32212331,-10.94997182,-12.81034616,-11.37790232,-12.93668108,-13.53571516,-7.773932814,-6.185260378 -761,F64E,-0.037619673,-1.145113425,-1.972874924,-2.068206371,-3.02234433,0.04696629,0.030016941,-0.105256286,,-1.107199067,-1.183027783,-2.04893611,-1.896813737,-2.132064134,-2.004348608,-2.663916225,-3.380772434,3.45357677,1.13492915,-12.76323986,-10.74397124,-12.83867902,-12.399368,-13.66450612,-14.16967491,-7.655104423,-6.177034591 -762,F64D,-0.033295451,-1.958808357,-2.139888578,-2.258098772,-3.075736094,0.030130053,0.018020975,-0.084611877,,-2.012386466,-1.905230248,-1.999880999,-2.279896157,-2.42979651,-2.086401033,-2.484527346,-3.666944842,2.515367619,-1.59410191,-15.8982201,-13.49726414,-17.40789885,-15.25777419,-17.42876489,-15.89939844,-9.940877565,-10.09132959 -763,F64G,-0.000137964,-1.669298778,-2.055692976,-2.209684094,-3.080549082,0.035771395,0.036574186,-0.036850114,,-1.806770087,-1.531827469,-2.209237968,-1.902147983,-2.116274734,-2.303093453,-2.773065562,-3.388032601,2.023405493,-1.628992269,-14.67804395,-13.71830597,-14.89361069,-14.26991566,-15.71274969,-14.79563773,-9.940877565,-10.09132959 -764,F64I,-0.009748667,0.023435533,-1.122824316,-1.801814432,-2.809557375,0.003588868,0.052482182,-0.071979516,,0.011708257,0.035162808,-0.743472092,-1.50217654,-1.87581814,-1.727810723,-2.80561024,-2.81350451,1.961784681,0.865883733,-8.656968736,-8.257107513,-5.875736061,-8.394733559,-10.53141696,-10.22584959,-5.507094299,-3.639622919 -765,F64H,-0.031702786,-0.371446054,-1.855072162,-2.214719148,-2.635383711,0.005981868,0.034147934,-0.097553506,,-0.281027276,-0.461864832,-1.74724859,-1.962895734,-2.034496598,-2.394941697,-2.487167442,-2.783599979,1.267511246,0.028652333,-12.27170628,-14.91300625,-11.72822225,-8.655014816,-12.59842937,-13.46385873,-6.865003678,-4.198040587 -766,F64K,-0.015607968,-0.894579352,-2.123853041,-2.582683853,-3.226927432,0.029842726,0.055787386,-0.087003322,,-1.008894313,-0.78026439,-1.919373662,-2.328332419,-2.553409156,-2.61195855,-2.784231251,-3.669623613,2.422120165,0.290970434,-14.11163622,-12.77386147,-14.10982631,-12.38772823,-15.50184618,-15.78491892,-7.499532143,-5.439412144 -767,F64M,-0.036484905,0.023722338,-0.01221472,-0.098431851,-1.78343415,-0.026789323,0.001281141,-0.074250951,,0.022417964,0.025026711,0.036704546,-0.061133985,-0.065886885,-0.130976816,-1.572683087,-1.994185213,0.879802373,1.329783233,-8.14933502,-7.332246315,-6.118420456,-7.981533592,-9.393772903,-9.920701836,-5.80238681,-2.78262693 -768,F64L,-0.005539031,0.01245872,-0.904360876,-1.830372352,-2.346558986,0.024664339,0.048682278,-0.059760339,,-0.020268098,0.045185538,-0.666526922,-1.14219483,-1.746807104,-1.913937599,-2.810138112,-1.88297986,2.065758208,0.972251407,-7.593871242,-6.963559631,-5.634145073,-7.054276176,-9.176542076,-9.140833252,-5.829044635,-2.596603433 -769,F64N,-0.039346988,-1.277772915,-2.565390548,-1.9020828,-3.191343685,0.018422714,-0.004995681,-0.073698294,,-1.146264604,-1.409281225,-1.978857177,-3.151923919,-2.135771416,-1.668394184,-2.843714766,-3.538972604,3.421659296,1.096727314,-16.03152285,-14.51413927,-17.83179681,-13.34323047,-16.68772018,-17.7807275,-9.779764857,-9.352302711 -770,F64Q,-0.052006576,0.021362063,-1.062696415,-1.857375187,-2.642892061,0.057610204,-0.00378812,-0.100225032,,0.01913441,0.023589716,-0.919373662,-1.206019167,-1.729500415,-1.985249958,-2.659292514,-2.626491607,2.371103898,1.132025689,-13.54362713,-11.03091702,-13.70962211,-13.08228495,-14.42407352,-15.47123804,-6.738277985,-3.936784335 -771,F64P,-0.002310352,-1.691576636,-2.192556612,-2.3301431,-2.735826052,0.027564906,0.032702596,-0.0373233,,-1.814836873,-1.568316399,-2.228300138,-2.156813086,-2.21451815,-2.44576805,-2.746370241,-2.725281863,2.415176178,-1.31048882,-13.85739738,-13.125533,-14.51842745,-13.34957873,-14.8191944,-13.47425335,-7.245096751,-5.700397604 -772,F64S,0.005165746,-0.925470176,-2.007173027,-2.422540943,-3.494443125,0.015783174,0.035549408,-0.025217916,,-0.881916945,-0.969023406,-2.206416694,-1.80792936,-2.580814877,-2.264267009,-3.510606977,-3.478279273,1.181513072,-0.444501162,-10.7208713,-10.3990014,-10.78474109,-9.711034172,-11.89410161,-10.81547824,-6.903568446,-5.701543529 -773,F64R,-0.01974513,-1.18384842,-2.144861517,-2.353320179,-3.301163574,0.050730748,0.021924507,-0.061414766,,-1.159270454,-1.208426386,-2.352819469,-1.936903565,-2.300474086,-2.406166272,-2.983593852,-3.618733296,1.271028951,-0.589383218,-13.59526792,-12.70852303,-10.41536175,-11.78033474,-15.43554123,-17.63657888,-6.550318602,-4.774481488 -774,F64T,0.011485381,-0.202048388,-1.515333579,-2.330658398,-2.630296893,0.012677202,0.035352269,-0.012381507,,-0.109214833,-0.294881942,-1.431665482,-1.599001675,-2.190639713,-2.470677082,-2.530606277,-2.729987509,0.960731058,0.075865773,-10.34940045,-9.705437851,-9.03081749,-10.6287285,-10.81334212,-11.5686763,-6.517542119,-4.917899263 -775,F64W,-0.020653294,-0.003878135,-0.110487266,-1.561012024,-2.549393345,0.014975277,0.010346714,-0.051653302,,-0.028651729,0.02089546,-0.119365749,-0.101608783,-1.345709513,-1.776314534,-2.554255214,-2.544531475,0.963764281,0.745863883,-11.08181953,-11.11045232,-11.88724066,-8.486794876,-12.13695214,-11.78765763,-6.091807964,-3.308432387 -776,F64V,0.009114989,-0.007850148,-0.00848575,-1.193081601,-2.270670191,0.001433514,0.045147071,-0.026917093,,-0.036288634,0.020588339,-0.012297396,-0.004674103,-0.637968115,-1.748195086,-2.223596872,-2.31774351,1.719863424,1.332249403,-7.797226328,-6.115346474,-6.138590279,-8.068065239,-9.556761116,-9.10736853,-5.398436101,-2.06766327 -777,F64Y,-0.012969563,0.015158217,0.006973345,0.027411037,-1.611485958,-0.023906392,0.011080446,-0.037019572,,0.011277452,0.019038982,0.03856884,-0.02462215,0.036435402,0.018386671,-1.602626658,-1.620345258,0.630179217,1.31220221,-7.542598911,-8.01515918,-9.12860836,-5.57043898,-8.447370796,-6.551417236,-4.2237465,-2.286461081 -778,P65A,-0.014314967,0.011552608,0.006077418,0.009572938,-1.414854298,0.036509902,0.009387425,-0.038017358,-0.026162439,0.022363176,0.000742039,0.012563841,-0.000409005,0.011216922,0.007928953,-1.393779639,-1.435928957,0.926957429,1.34849867,-5.368892606,-5.793093781,-5.586125313,-4.344099937,-6.475211792,-4.645932205,-5.053259387,-0.958658655 -779,P65C,-0.024244545,0.029899921,-0.104559116,-1.512368547,-3.03405659,0.140301902,0.003760695,-0.052249785,-0.04895053,0.042251142,0.0175487,-0.076336087,-0.132782145,-1.40714071,-1.617596383,-2.542710459,-3.525402721,0.838573874,0.723701128,-12.71509686,-11.83436613,-12.50607805,-14.04272374,-14.33311012,-10.85920627,-8.46723573,-4.670034299 -780,P65E,-0.076936322,0.007836666,-1.08778714,-2.056855574,-3.178608368,-0.011789808,-0.081631614,-0.07224103,0.011787229,-0.009925891,0.025599223,-0.673991837,-1.501582443,-1.962831959,-2.150879189,-2.797371712,-3.559845023,1.862931077,0.803711694,-13.69747834,-12.4092963,-15.51843599,-13.97775693,-16.37844583,-10.20345666,-8.786477949,-4.075681959 -781,P65D,-0.007828136,-0.512012328,-1.829379806,-1.950976982,-3.015758099,0.036723431,0.019961494,-0.035617765,-0.00619855,-0.362839721,-0.661184934,-1.681390973,-1.977368638,-2.131382003,-1.77057196,-2.664891761,-3.366624437,2.709412239,0.962409766,-14.18483879,-12.55095097,-15.25666372,-15.58529152,-15.53070547,-12.00058225,-9.169106934,-5.394382588 -782,P65G,-0.021974703,-0.003964627,-0.03512254,-1.671626394,-2.824370872,0.050792686,0.001678422,-0.045627827,-0.020297183,-0.013286335,0.005357081,-0.06292307,-0.007322009,-1.371077783,-1.972175004,-2.501684112,-3.147057632,0.703890451,0.714856285,-11.1458355,-10.25039447,-11.65426146,-9.963110054,-15.38340816,-8.478003357,-6.856502364,-3.243425637 -783,P65F,-0.076725859,-0.022937487,-0.380402994,-1.871867945,-2.646213716,0.073839195,-0.00810489,-0.145346828,-0.206232703,0.032546508,-0.078421482,-0.223213913,-0.537592074,-1.305228159,-2.43850773,-2.382805961,-2.909621471,1.516513564,0.884411531,-13.64491739,-13.57938696,-12.04161774,-17.99358546,-14.26436367,-10.34563309,-8.327905156,-4.784129655 -784,P65I,-0.046100929,0.018896787,0.022447619,-2.088445221,-2.414665711,0.014761454,-0.040483537,-0.051718321,-0.119277061,0.042284461,-0.004490888,0.047029071,-0.002133834,-1.625678431,-2.551212011,-1.98309693,-2.846234492,0.590865189,0.687786309,-11.3728154,-10.3044072,-11.08411542,-11.46849491,-15.36621362,-8.640845848,-7.781307439,-3.802290053 -785,P65H,-0.036473154,0.016670462,-0.016075728,-0.96000361,-2.194988422,0.064508101,-0.004853212,-0.068093095,-0.045575944,0.017317285,0.016023638,-0.031141496,-0.00100996,-0.711383366,-1.208623853,-2.100210329,-2.289766515,1.868632593,1.399528087,-12.07621915,-11.18357777,-10.87283597,-15.87225877,-12.19385343,-10.25856979,-7.679228848,-2.672501875 -786,P65K,0.011009463,0.030209235,0.062500064,-1.62078334,-2.53504946,-0.009152217,0.056867235,-0.034848309,-0.068845359,-0.048973345,0.109391814,0.034664567,0.090335561,-1.139602333,-2.101964347,-2.451263342,-2.618835578,0.701273183,0.733286747,-13.45046829,-12.50085229,-13.93208151,-13.78073704,-15.97346814,-11.06520245,-7.992176742,-4.097087225 -787,P65M,0.098401804,0.015083722,-1.290873375,-2.264831718,-2.591052208,0.014229945,0.128848916,0.067954691,-0.008126608,0.020146575,0.010020868,-0.966405564,-1.615341186,-2.297210187,-2.232453248,-2.052568694,-3.129535721,1.816676486,0.481033193,-9.332142043,-8.559300056,-10.01375991,-9.64707238,-12.57203146,-5.86854641,-6.756379475,-4.285118399 -788,P65L,-0.014751306,0.014214879,-0.337966223,-1.693614309,-2.303535144,0.017136393,0.021866475,-0.051369086,-0.030692436,-0.010153245,0.038583002,-0.238325049,-0.437607397,-1.539399627,-1.847828991,-2.274554748,-2.33251554,1.360870581,0.785342701,-7.821619812,-7.305230057,-7.285926399,-7.921430946,-12.9168375,-3.678674156,-4.940324523,-2.730452866 -789,P65N,-0.013402401,-0.027247977,0.058529588,-1.108020144,-2.464589554,0.000522434,-0.006257991,-0.02054681,-0.14542164,0.005986197,-0.06048215,0.074214093,0.042845083,-0.687530799,-1.528509489,-2.044949297,-2.884229811,1.856859485,1.412617518,-13.44981071,-12.46526845,-12.7715477,-15.56986079,-15.57950259,-10.86287403,-8.352456782,-4.645971957 -790,P65Q,-0.083736248,-0.053953462,-0.197807731,-1.608503708,-2.323799824,0.108071203,-0.043994341,-0.123478154,-0.031140972,-0.050201259,-0.057705664,-0.150157093,-0.245458368,-1.673866474,-1.543140942,-2.332314969,-2.315284679,1.220030172,0.738112321,-11.99934235,-12.17420722,-13.28824072,-12.35583136,-13.39352733,-8.784905098,-7.75039976,-3.203717795 -791,P65S,-0.024183394,-0.003306002,0.012245588,-0.178302774,-1.91444365,0.050568825,-0.010254133,-0.038112654,-0.026142497,-0.009603834,0.002991831,0.012184644,0.012306532,-0.121183368,-0.235422179,-1.549463978,-2.279423321,1.057259064,1.349105188,-10.54720749,-10.15560621,-9.197173599,-11.31379551,-12.92093925,-9.148522903,-7.127304313,-2.671539149 -792,P65R,-0.002576072,-0.029280011,-1.41606579,-2.124913176,-2.915843129,0.060691512,0.028468487,-0.033620631,-0.078902444,-0.031363245,-0.027196777,-1.338276189,-1.493855391,-2.040691882,-2.20913447,-3.02649931,-2.805186948,2.385289069,0.901142051,-11.07453513,-11.38429401,-10.62846519,-11.67589157,-13.25863512,-8.425389771,-7.584570327,-3.096860067 -793,P65T,-0.072020972,-0.015292307,-0.011117082,-1.564312597,-2.386225246,0.034033302,-0.047858254,-0.09618369,-0.011559784,-0.01414397,-0.016440643,0.021652362,-0.043886526,-1.265430107,-1.863195087,-2.241847019,-2.530603473,0.828908773,0.736078691,-10.03961451,-9.303601517,-10.05400492,-10.78871479,-11.48953835,-8.562212959,-7.317749571,-3.093994637 -794,P65W,-0.015388326,-0.284308487,-1.689654983,-2.598446441,-3.339318818,0.034518468,0.007471455,-0.038248106,-0.042449308,-0.175044866,-0.393572108,-1.712091225,-1.667218741,-2.764142247,-2.432750635,-2.996622009,-3.682015627,0.915470994,0.003368363,-15.29183539,-13.81318473,-16.33257647,-17.13588286,-17.25705077,-11.92048213,-9.924382312,-6.361046556 -795,P65V,-0.005848987,0.058583367,0.063954856,-0.991079931,-2.560355514,0.088154658,0.014186597,-0.02588457,-0.053251362,0.041765019,0.075401715,0.055776899,0.072132812,-0.560689622,-1.42147024,-2.116976595,-3.003734433,1.647382433,1.352200184,-9.650531458,-9.659339775,-9.283623413,-9.695755516,-13.65193146,-5.962007126,-6.960253441,-2.109906444 -796,P65Y,0.059737517,0.092076196,-0.244196248,-1.675778328,-2.809710795,0.039512484,0.108559322,0.010915712,0.048510036,0.066164981,0.117987411,-0.184461324,-0.303931172,-1.554575681,-1.796980975,-2.486025448,-3.133396142,1.110789443,0.738253207,-14.72559443,-11.97753706,-14.41857256,-19.43801533,-15.45878616,-12.33506106,-7.680588175,-2.414636544 -797,M66A,-0.018477378,0.015334467,0.015844945,0.023224095,-1.654670825,0.044304058,0.008395577,-0.045350333,-0.074818127,0.006055871,0.024613063,0.042062311,-0.010372422,-0.002296203,0.048744392,-1.42687073,-1.88247092,0.665805741,1.322857457,-8.612746361,-9.629804688,-9.860213493,-9.35600885,-6.553660881,-7.664043892,-6.247542482,-0.555128583 -798,M66C,-0.041226202,0.017245418,-0.003129543,0.009030523,-1.526861034,0.003542534,-0.060026919,-0.022425484,-0.146891285,-0.027828534,0.062319369,-0.000897981,-0.005361105,-0.049358921,0.067419967,-1.503323311,-1.550398757,0.723806815,1.322689162,-12.35013934,-12.23689363,-12.48839301,-13.02649379,-10.4351709,-13.56374538,-7.758691001,-6.044103914 -799,M66E,-0.04590084,-0.20613688,-1.537494224,-2.19368571,-3.077086547,0.067039456,-0.009428305,-0.082373375,-0.119810341,-0.045585838,-0.366687922,-1.270989557,-1.80399889,-1.997927659,-2.389443761,-2.470649199,-3.683523895,2.758906919,1.251685956,-13.00370005,-13.92857339,-12.7732355,-13.51667011,-10.24239192,-14.55762933,-8.243294148,-6.817865588 -800,M66D,-0.040833646,-1.52638438,-1.972504373,-1.978479937,-3.33080682,0.023599262,-0.025637942,-0.05602935,-0.247594145,-1.426013919,-1.62675484,-2.054452452,-1.890556293,-2.076668221,-1.880291652,-3.072268505,-3.589345134,3.351215222,0.901056436,-14.40108427,-14.23587167,-14.45002978,-14.63805569,-11.39648042,-17.28498377,-9.455016926,-9.27429895 -801,M66G,-0.053145706,0.010669431,0.001864735,-0.06405898,-1.892259959,0.055041003,-0.032001964,-0.074289448,-0.065162076,0.034804966,-0.013466104,0.042681817,-0.038952347,-0.06396408,-0.06415388,-1.729482572,-2.055037345,0.725602136,1.312383234,-12.96721904,-12.65463089,-12.38970042,-13.51684748,-10.3197886,-15.95512783,-6.823025425,-4.848255533 -802,M66F,-0.025169408,0.048467643,-0.003811328,0.015262599,-0.487952175,0.077275666,-0.022324929,-0.028013887,-0.055781329,0.04607116,0.050864126,0.016816283,-0.024438938,-0.040311711,0.070836909,-0.352086117,-0.623818233,1.300046517,1.832522642,-7.7777883,-7.122374619,-5.873723991,-7.536209503,-7.44499865,-10.91163474,-3.45479496,-1.561841817 -803,M66I,0.027529546,-0.030403865,-0.021759397,0.020276405,-0.176145829,-0.05477336,0.02508021,0.029978882,-0.064598962,-0.058242715,-0.002565014,-0.008828951,-0.034689843,-0.034540066,0.075092875,-0.098405183,-0.253886475,1.350331183,2.292463867,-4.471891563,-3.765870277,-4.51866745,-4.700688599,-3.424503555,-5.949727936,-4.24406619,-2.357611432 -804,M66H,-0.024175019,0.000533706,-0.014147417,-0.0485973,-1.920554511,0.042019846,-0.000578877,-0.04777116,-0.082013703,-0.009057119,0.010124531,-0.01685438,-0.011440453,-0.059507278,-0.037687321,-1.78621729,-2.054891731,0.906948565,1.317751722,-11.68956298,-10.35392963,-10.24130968,-13.27693059,-9.595164665,-14.98048032,-5.458169513,-3.037527056 -805,M66K,0.013453243,-1.365852074,-2.353720856,-2.4491385,-3.093978709,0.060589001,0.042931791,-0.016025305,-0.200628766,-1.505972542,-1.225731605,-2.244286065,-2.463155647,-2.521774339,-2.37650266,-2.438193378,-3.74976404,0.712534115,-0.959377521,-13.30454448,-13.74884412,-13.64579363,-14.08646209,-10.12295575,-14.91866682,-9.380420643,-8.976044596 -806,M66L,0.010496515,0.011515403,0.02121233,0.008152147,-0.054318447,-0.009960666,0.0062425,0.014750529,-0.073227303,0.003723451,0.019307355,0.033918365,0.008506295,-0.033652615,0.049956908,-0.020482383,-0.08815451,1.216325745,2.462144269,-1.534105042,-1.114103386,-1.735543365,-1.83298275,-0.367447838,-2.620447868,-1.790923645,-0.626470676 -807,M66N,-0.059014943,-0.034475008,-1.267502896,-2.050948181,-3.030291781,0.034619947,-0.042977175,-0.075052711,-0.008511418,-0.03463768,-0.034312335,-1.072011606,-1.462994186,-2.065503223,-2.036393138,-2.981922262,-3.078661299,2.182341146,0.842551809,-14.05437822,-13.42929005,-13.05202569,-14.67120139,-10.83099105,-18.28838294,-9.455016926,-9.27429895 -808,M66Q,-0.023585763,0.024812324,0.02141854,-0.082957833,-2.039269583,0.050383575,-0.003667515,-0.04350401,-0.075899808,0.032253262,0.017371386,0.05655039,-0.013713311,-0.07541945,-0.090496215,-1.760934354,-2.317604812,0.813977711,1.313399619,-9.611465596,-10.95479543,-9.378733978,-9.685070595,-6.582183655,-11.45654433,-5.483093729,-2.453323429 -809,M66P,-0.019193346,-0.519333527,-1.693169217,-2.169857775,-3.102249124,0.044302248,0.001329703,-0.039716394,-0.016076137,-0.424405644,-0.614261409,-1.614595864,-1.77174257,-2.092743588,-2.246971962,-2.854260667,-3.35023758,2.702519691,0.972471,-11.38778756,-11.95941073,-11.52832517,-12.8295838,-9.15344973,-11.46816839,-6.206685913,-3.320250778 -810,M66S,-0.022181653,0.035280098,0.00772585,-1.483408318,-2.363766686,0.017875812,0.000625946,-0.044989251,-0.075959506,0.041143001,0.029417194,0.016819133,-0.001367433,-1.162779884,-1.804036751,-2.170279392,-2.55725398,0.652395837,0.726664005,-10.50641447,-9.624621552,-9.976209557,-11.21477529,-6.906093773,-14.8103722,-5.282427157,-1.155982599 -811,M66R,-0.026070605,-1.298873657,-2.107423854,-2.581857978,-3.001973273,0.070585812,0.00385321,-0.05599442,-0.118329539,-1.349031637,-1.248715677,-2.17522049,-2.039627217,-2.526494978,-2.637220978,-2.795096534,-3.208850012,0.567058216,-0.814341546,-13.55384705,-13.99313988,-13.32657004,-14.23486736,-10.65178967,-15.56286829,-9.455016926,-9.27429895 -812,M66T,-0.018051514,0.025649935,0.018232183,0.006369444,-1.420158937,0.044127829,-0.012861124,-0.023241903,-0.095227956,0.011312359,0.03998751,0.004327924,0.032136442,-0.033258015,0.045996902,-1.425003701,-1.415314173,0.825793265,1.335626323,-7.4558965,-7.432700302,-7.462693237,-8.288435852,-5.184290459,-8.911362648,-4.81611863,-1.394418984 -813,M66W,-0.031820963,-0.475738042,-1.636609335,-2.347251439,-3.355591012,0.019395275,-0.021396135,-0.042245791,-0.09466632,-0.40083401,-0.550642074,-1.574982534,-1.698236135,-2.454530799,-2.239972078,-3.274039824,-3.437142199,1.637561852,0.183601024,-13.12873119,-12.91194832,-12.24995651,-12.81023176,-11.83610061,-15.83541877,-8.452370444,-6.928005902 -814,M66V,-0.002282773,0.038642623,0.019164912,0.003847548,-0.098950592,-0.012662831,-0.00591711,0.001351564,-0.129880203,0.023072669,0.054212576,0.032630157,0.005699666,-0.033314116,0.041009212,-0.076054262,-0.121846921,1.458404071,2.473539228,-4.831133493,-4.753843147,-4.989405518,-4.673658211,-3.351921959,-6.386838631,-3.848031878,-2.869577149 -815,M66Y,-0.047952653,-0.016218227,0.011545639,-1.324359782,-2.749518565,0.031386775,-0.028981444,-0.066923862,-0.150424913,-0.006253871,-0.026182583,0.022239459,0.000851819,-0.962782125,-1.685937439,-1.987540639,-3.51149649,2.154303806,1.523136309,-12.07770012,-11.28361041,-10.12142515,-12.26257404,-11.15295093,-15.56794007,-5.329543049,-1.60126592 -816,M67A,0.041274409,0.036463102,0.045381773,0.022448773,-0.004768182,0.039407992,0.019126682,0.063422136,0.080020344,0.025041988,0.047884216,0.070941746,0.0198218,0.019798996,0.02509855,-0.03101826,0.021481896,1.114053806,2.46394564,-5.97247477,-4.994473778,-6.342070435,-5.407921165,-7.179390274,-5.938518196,-2.967422985,2.502068199 -817,M67C,-0.285901642,-0.267102143,-0.162615102,-0.100863608,-0.247812065,0.491398329,-0.341717762,-0.230085522,0.425930161,-0.031570854,-0.502633431,-0.10148486,-0.223745344,0.016894958,-0.218622173,-0.147748852,-0.347875277,1.308930301,2.109685547,-6.574272098,-6.503120781,-5.065774162,-7.185726494,-7.088285362,-7.02845369,-3.69076917,1.688979744 -818,M67E,-0.021812481,0.015047528,0.021335598,-1.607073473,-2.184542596,-0.021067369,-0.011352008,-0.032272954,0.025435554,0.049924562,-0.019829507,0.076054445,-0.03338325,-1.442590256,-1.771556689,-2.319767662,-2.04931753,0.520289223,0.697821937,-10.33133629,-8.715245888,-8.069143341,-10.50625233,-13.17024632,-11.19579358,-5.841744053,-2.767698938 -819,M67D,0.033463157,0.047099423,0.043524403,-0.058463889,-2.285650341,0.053031825,0.051791423,0.01513489,0.117349821,0.038298975,0.055899871,0.041008891,0.046039915,0.00960841,-0.126536188,-1.87474758,-2.696553101,0.739872275,1.304311377,-8.026353607,-6.453738846,-7.234649277,-8.624408463,-9.255814888,-8.563156563,-5.169525647,-2.959472503 -820,M67G,0.043927488,0.03253344,0.035252798,0.016393647,-0.03955652,-0.102482728,0.010940336,0.07691464,0.074948537,0.023312764,0.041754116,0.044393691,0.026111904,0.021796616,0.010990678,-0.038998372,-0.040114667,1.182770114,2.426226416,-8.374982378,-7.279254066,-7.356561829,-8.660215263,-9.164696808,-9.414183922,-4.518103308,-1.054475656 -821,M67F,0.083709323,0.064480916,0.050637205,-1.048492098,-2.040629435,-0.002909219,0.096714057,0.070704589,0.039849986,0.04480338,0.084158451,0.046158641,0.055115768,-0.751372021,-1.345612174,-1.892342697,-2.188916173,2.011203346,1.518490046,-8.910077664,-9.151378532,-7.665790993,-7.519482704,-10.58444021,-9.629295883,-6.08864444,-3.720615376 -822,M67I,0.008764232,-0.013699198,-0.030579772,-0.009333499,-1.283578119,-0.09929467,-0.002336164,0.019864628,0.081716572,-0.006034527,-0.021363869,-0.011122474,-0.050037069,-0.019892219,0.001225222,-1.20627444,-1.360881798,0.775016594,1.345960645,-6.617888905,-6.457860329,-7.277482704,-6.574077209,-7.172036583,-5.607987701,-6.863258047,-4.339873322 -823,M67H,0.038810047,0.019228775,0.03650962,0.033339063,-1.556438761,0.022097475,0.009823917,0.067796176,0.03354875,0.022193486,0.016264064,0.035746943,0.037272297,0.018453227,0.048224898,-1.223871674,-1.889005848,0.710296983,1.33981787,-11.04499814,-8.91560154,-8.178470978,-12.86380316,-13.63545108,-11.63166394,-6.083484284,-2.677670276 -824,M67K,-0.019451849,-0.179492392,-1.697063716,-2.467942159,-2.969365791,0.017994551,0.004223585,-0.043127283,0.041115673,-0.071502615,-0.287482168,-1.53379377,-1.860333662,-2.87781195,-2.058072367,-2.412566675,-3.526164906,0.754890859,0.03275763,-11.23512407,-10.45568147,-9.470303574,-11.65361331,-13.34326442,-11.25275758,-8.390336279,-7.399047766 -825,M67L,0.019574852,0.040355645,0.030829856,-0.003462612,-0.449230009,-0.082224526,-0.007639496,0.046789199,0.055581853,0.048515153,0.032196137,0.059434201,0.00222551,0.020531066,-0.027456289,-0.334647855,-0.563812162,1.03251495,1.675100715,-2.614116527,-3.161647507,-2.426969795,-2.834422585,-1.92611274,-2.721430008,-3.984816939,-0.278442438 -826,M67N,0.020804911,0.049890496,0.040865608,0.014451331,-0.007628561,0.087542043,0.005164126,0.036445696,0.079850242,0.041171217,0.058609774,0.081374525,0.000356691,0.023875829,0.005026832,-0.007977988,-0.007279134,1.306073461,2.540505309,-4.073840581,-3.47325927,-2.68507943,-4.997464272,-5.637300896,-3.576099037,-3.090289505,-0.521147587 -827,M67Q,-0.028106246,-0.012759333,-0.054587134,0.030859851,-1.098948294,0.105638142,-0.008048122,-0.04816437,0.003375917,0.017606296,-0.043124961,-0.035738608,-0.073435659,0.049900512,0.01181919,-0.664378648,-1.533517939,0.622182293,1.384600014,-8.695790123,-6.868628136,-5.749395653,-9.100534874,-10.88453567,-10.87585629,-4.889685237,0.592894728 -828,M67P,-0.031212695,-1.585740802,-2.344644632,-2.371231389,-2.755756325,0.035931549,-0.012038523,-0.050386866,-0.0950204,-1.697037536,-1.474444067,-2.649838142,-2.039451122,-2.370607032,-2.371855746,-2.604331761,-2.907180889,-0.191687138,-1.100310536,-12.78184855,-12.05338488,-11.65326329,-12.70625984,-14.06418129,-13.43215345,-8.390336279,-7.399047766 -829,M67S,0.023886261,0.022876727,0.031380819,0.005506279,-0.10032247,-0.100766495,0.004342735,0.043429787,0.091359961,0.027069972,0.018683481,0.068164167,-0.00540253,-0.004703409,0.015715967,-0.118357445,-0.082287494,1.401050094,2.322254221,-5.3991243,-4.817881859,-4.96699118,-7.487386116,-5.431356705,-4.292005638,-3.368360391,-1.195426744 -830,M67R,-0.02531785,-0.463547688,-1.771474291,-2.217430181,-2.942099013,0.008096506,-0.033688097,-0.016947603,0.035550664,-0.398505349,-0.528590026,-1.747224902,-1.795723679,-2.233910586,-2.200949775,-2.768665311,-3.115532714,1.426673882,0.053629948,-13.62442921,-11.7496193,-11.73669692,-14.00280697,-15.77527293,-14.85774992,-8.390336279,-7.399047766 -831,M67T,0.02386907,0.013818978,0.050287824,0.012335575,-0.062693547,-0.082457579,0.008068071,0.039670068,0.050768912,0.025340032,0.002297923,0.050203033,0.050372614,0.001294481,0.023376668,-0.060961919,-0.064425174,1.301915003,2.424270789,-4.841839943,-5.136262032,-4.113960815,-5.284327385,-5.621512207,-4.053137276,-3.756399199,-1.265326492 -832,M67W,-0.012379145,-0.608258264,-1.70148854,-2.163975358,-2.776323366,-0.027639429,-0.005823961,-0.018934328,0.006355651,-0.549179964,-0.667336564,-1.638668789,-1.764308291,-2.271482508,-2.056468208,-2.505207238,-3.047439493,2.95324871,1.105490899,-11.54143914,-11.13045979,-9.94939344,-10.4027261,-13.54849153,-12.67612483,-7.560676787,-5.021316166 -833,M67V,0.029725298,0.020631657,0.03641298,0.0171589,-0.205803582,-0.095985972,0.009751423,0.049699173,0.023234506,0.024394469,0.016868844,0.064277188,0.008548772,0.017740041,0.016577759,-0.179142174,-0.232464989,1.276108129,2.072543987,-7.083968565,-6.014704689,-6.527889763,-5.819602493,-6.68602433,-10.37162155,-5.123803137,-2.918821228 -834,M67Y,0.059796775,0.002666973,-1.373296289,-2.083085674,-2.869177379,-0.038763141,0.041272863,0.078320686,0.060616347,-0.007079894,0.01241384,-1.415812457,-1.330780121,-2.127807422,-2.038363925,-2.75947216,-2.978882598,2.300551988,0.8052038,-10.50726689,-10.35554903,-9.286521339,-9.392553848,-12.1698839,-11.33182632,-6.259522166,-2.337421261 -835,S68A,-0.000202248,-1.564852456,-1.954407739,-2.211910343,-3.369026655,-0.101700699,-0.015787593,0.015383097,-0.175361047,-1.614956894,-1.514748018,-2.050105244,-1.858710233,-2.104798917,-2.319021768,-3.155899188,-3.582154121,0.64191049,-0.988623643,-8.134089592,-8.392843658,-9.032691727,-7.309401955,-7.639710365,-8.295800255,-7.257221025,-7.241972444 -836,S68C,-0.057817662,-0.312383092,-1.855706283,-2.006392902,-2.383237094,-0.00892494,-0.033056525,-0.082578798,-0.024827425,-0.149977208,-0.474788975,-1.682128458,-2.029284107,-1.693356438,-2.319429365,-2.139119008,-2.62735518,3.851583142,2.221694085,-9.060234192,-9.875024559,-10.09069373,-7.291008263,-9.264254524,-8.78018988,-6.985296891,-6.250451757 -837,S68E,-0.05927591,-2.233223929,-2.607048934,-2.90825055,-3.358158761,-0.105697017,-0.051224826,-0.067326993,-0.284920526,-2.74268016,-1.723767698,-2.792477629,-2.421620238,-2.803705609,-3.012795491,-3.053173533,-3.663143988,1.306640742,-1.679156348,-11.38701376,-11.12287834,-11.64882794,-10.37232729,-11.30070462,-12.49033062,-9.121662103,-11.46630438 -838,S68D,-0.048039022,-1.785726597,-1.980713187,-2.441294185,-3.192232391,-0.091213523,-0.0000712,-0.096006843,-0.237193654,-1.95602497,-1.615428223,-2.306852434,-1.654573939,-2.318080414,-2.564507955,-2.868578335,-3.515886447,-0.119915058,-1.205532149,-10.70382442,-10.04070176,-11.36037969,-9.600171989,-10.84679685,-11.67107182,-8.253840805,-8.223226532 -839,S68G,-0.00796827,-1.566966938,-2.170618886,-2.325082074,-2.577396086,-0.108952193,0.00386237,-0.019798909,-0.157581073,-1.567172159,-1.566761716,-2.223350992,-2.11788678,-2.456427722,-2.193736426,-2.404865651,-2.74992652,0.085556897,-1.051798503,-6.75427664,-6.529896133,-7.804829971,-5.287579018,-6.818053932,-7.331024147,-6.1429494,-4.624739989 -840,S68F,-0.033700172,-1.458205662,-2.347012278,-2.08304701,-2.859561477,0.011023213,0.003936784,-0.071337128,0.177492533,-1.494803126,-1.421608197,-1.942540603,-2.751483952,-1.777677324,-2.388416696,-2.504266503,-3.214856451,-0.467134612,-0.894969026,-12.54578895,-11.37343853,-14.63639021,-11.00025938,-12.49377458,-13.22508203,-9.121662103,-11.46630438 -841,S68I,-0.19269458,-1.011795656,-1.252963438,-1.089912263,-1.65252998,0.028774228,-0.119899659,-0.265489501,-0.12032555,-1.010223079,-1.013368232,-1.435684161,-1.070242714,-1.071248527,-1.108575999,-1.696380066,-1.608679894,4.020810838,2.55242961,-12.16198637,-10.95683016,-14.67990908,-10.63302402,-11.88560139,-12.65456718,-9.096857065,-11.2243909 -842,S68H,-0.044997535,-1.681058254,-2.523211925,-2.145922842,-2.973291757,-0.064951907,-0.048955023,-0.041040046,-0.220307509,-1.748006327,-1.614110181,-2.83919648,-2.20722737,-2.00532642,-2.286519263,-2.798862389,-3.147721125,0.195895406,-1.137779366,-11.87977776,-10.8951833,-12.78887261,-10.56518916,-11.70219681,-13.44744691,-9.121662103,-11.46630438 -843,S68K,-0.07462216,-1.75206569,-2.583552916,-2.646193905,-2.945587118,0.047307876,0.052592873,-0.201837193,-0.124353039,-2.017681871,-1.486449509,-2.368509335,-2.798596496,-2.379737315,-2.912650495,-2.62920524,-3.261968996,-0.282312086,-1.152196194,-11.61756844,-10.81608961,-12.26726938,-10.53206288,-11.52999226,-12.94242806,-9.121662103,-11.46630438 -844,S68M,-0.102365858,-2.123151331,-2.565562932,-2.071232245,-2.927597134,0.071377414,-0.098907007,-0.105824709,0.144492273,-1.941047814,-2.305254848,-2.291875278,-2.839250585,-2.303103258,-1.839361232,-2.552571183,-3.302623085,-0.656026748,-1.080987751,-12.11153613,-11.12507278,-13.75415336,-10.70319332,-11.94962793,-13.02563326,-9.121662103,-11.46630438 -845,S68L,-0.083205,-1.753647119,-2.47089468,-2.42659576,-3.081591203,0.015773308,-0.07498041,-0.091429589,-0.115341506,-1.875922633,-1.631371605,-2.828810088,-2.112979272,-2.362916813,-2.490274706,-2.913414734,-3.249767671,-0.238838615,-1.13349804,-12.26772008,-11.20908527,-14.11940754,-10.76326065,-12.40191888,-12.84492806,-9.121662103,-11.46630438 -846,S68N,-0.14518617,-1.592905057,-1.711407917,-1.753352563,-2.096320864,-0.027951397,-0.072037021,-0.218335318,-0.089590933,-1.5653842,-1.620425914,-1.916211664,-1.506604169,-1.626409648,-1.880295478,-2.176907569,-2.015734159,4.232192503,1.904566711,-10.72556892,-10.46418092,-11.26378371,-9.641133247,-10.83990746,-11.41883926,-8.695813849,-9.295201633 -847,S68Q,-0.078034194,-1.779952051,-2.258041605,-2.203640992,-2.89210983,-0.071627005,-0.077388379,-0.078680008,-0.325921598,-1.650285306,-1.909618795,-2.139415468,-2.376667742,-1.974552189,-2.432729794,-2.400111373,-3.384108286,0.58167221,-1.09566034,-11.64948205,-11.04682595,-12.37666847,-10.50819782,-11.47137964,-12.84433836,-9.121662103,-11.46630438 -848,S68P,-0.037315548,-1.602907115,-2.123492316,-2.31595196,-3.316045444,-0.000148793,0.000589705,-0.0752208,-0.093925578,-1.595146315,-1.610667915,-2.189011828,-2.057972804,-2.258231754,-2.373672166,-2.788526289,-3.843564598,-0.08196982,-1.04648909,-10.30732778,-9.763371368,-11.21548335,-8.941861404,-10.02911348,-11.5868093,-8.221768715,-8.223226532 -849,S68R,-0.002923391,-1.619947014,-2.125689924,-2.209027256,-2.991039415,0.061159228,-0.002443422,-0.003403359,-0.188149492,-1.727277347,-1.512616681,-2.277677166,-1.973702681,-2.243147655,-2.174906856,-2.679702223,-3.302376607,-0.330303709,-1.155592843,-11.48284769,-10.79484264,-12.39500203,-10.14673496,-11.05967715,-13.01798167,-8.719616781,-9.281815226 -850,S68T,-0.058477074,-1.440474912,-1.962027363,-2.087137721,-2.713137191,-0.005313177,-0.068223376,-0.048730771,-0.083676882,-1.674975245,-1.205974579,-1.833917183,-2.090137543,-2.213121948,-1.961153493,-2.638681132,-2.787593249,-0.10277578,-1.065789799,-10.4788174,-10.45119284,-10.81506612,-9.903008537,-10.20273798,-11.0220815,-9.121662103,-11.46630438 -851,S68W,-0.055011448,-1.758212307,-2.323615122,-2.158290134,-3.346758972,0.00609287,-0.031404711,-0.078618185,-0.072216837,-1.772041451,-1.744383163,-1.879830866,-2.767399378,-2.037186882,-2.279393386,-2.985624811,-3.707893132,-0.004982928,-1.053660497,-12.38892633,-11.21858965,-13.98785825,-10.87713127,-12.24973358,-13.6113189,-9.121662103,-11.46630438 -852,S68V,-0.074445829,-1.85528656,-2.248222883,-2.333742618,-2.570666462,0.014353853,-0.051770046,-0.097121612,-0.17556096,-2.099742763,-1.610830356,-1.994638272,-2.501807494,-2.227715001,-2.439770234,-2.556364172,-2.584968752,-0.390045621,-1.182754695,-11.87420628,-10.96888941,-14.24413394,-10.32636668,-11.49479956,-12.33684179,-9.121662103,-11.46630438 -853,S68Y,-0.150662618,-1.672354001,-2.376204974,-2.225861597,-2.976799803,0.063606768,-0.054873478,-0.246451757,-0.156537723,-1.626082041,-1.71862596,-2.374849513,-2.377560434,-2.085047497,-2.366675696,-2.635545418,-3.318054188,0.134915438,-1.064738715,-12.67955283,-11.30107623,-14.63900039,-10.94191851,-12.36932961,-14.14643943,-9.121662103,-11.46630438 -854,T69A,-0.051391062,0.01358255,-0.379808289,-1.731622716,-2.759739677,-0.009190565,-0.035710917,-0.067071206,-0.039254142,0.018514753,0.008650346,-0.281389363,-0.478227214,-1.500595076,-1.962650355,-2.494313057,-3.025166296,1.428041618,0.810208919,-7.415588536,-7.942192314,-6.812993622,-8.113622444,-7.231685112,-6.977449188,-6.688879004,-3.353577068 -855,T69C,-0.048560088,0.034575041,0.005548795,-0.66715546,-1.764699631,0.005658811,-0.050667661,-0.046452515,-0.056485386,0.043410376,0.025739706,-0.011442664,0.022540254,-0.370065231,-0.964245689,-1.614145118,-1.915254143,1.599704637,1.453289965,-12.8616503,-13.46987543,-12.34620876,-11.3408198,-13.63874135,-13.51260616,-8.08551869,-4.144376909 -856,T69E,-0.043355236,-0.088709168,-1.57879016,-2.32013121,-3.195768026,0.063972286,-0.044128915,-0.042581556,-0.020549575,-0.037341334,-0.140077001,-1.487317811,-1.670262509,-2.187795065,-2.452467354,-2.625210545,-3.766325507,0.7414875,0.032880436,-15.00102397,-16.20409887,-12.32520458,-14.75901844,-15.33641184,-16.38038609,-11.19462357,-10.07581263 -857,T69D,-0.06617922,-1.387517722,-1.994767061,-2.671883298,-3.265384399,-0.033359528,-0.066500928,-0.065857511,-0.005773021,-1.235857439,-1.539178004,-1.973984384,-2.015549737,-2.71067381,-2.633092785,-2.92624054,-3.604528257,0.417008922,-0.73024674,-14.90185895,-16.39866489,-13.05007192,-13.64129629,-15.00879159,-16.41047008,-9.090674767,-5.602314758 -858,T69G,-0.052395547,0.02712598,-1.070905991,-2.045712326,-2.628796876,-0.001301949,-0.046700667,-0.058090427,-0.032376883,0.024617084,0.029634876,-0.867342851,-1.27446913,-1.978020155,-2.113404496,-2.69242739,-2.565166362,2.018730707,0.831264621,-13.94326667,-15.09630908,-11.5605393,-12.86209894,-15.12925217,-15.06813388,-9.044720475,-4.905328363 -859,T69F,-0.071454426,-0.801645658,-1.826176625,-2.111817795,-3.33535459,0.029183406,-0.041299368,-0.101609484,-0.07596699,-0.705436688,-0.897854627,-1.878097444,-1.774255805,-1.915816866,-2.307818724,-2.976481636,-3.694227544,3.178794579,1.23013718,-18.88107499,-20.9565415,-19.76542342,-15.7479194,-20.22785215,-17.70763847,-11.19462357,-10.07581263 -860,T69I,-0.058369356,0.021225323,0.020425741,-0.724221284,-1.685743653,-0.067037395,-0.044487496,-0.072251216,0.051696764,0.034887178,0.007563467,-0.024033356,0.064884838,-0.326826682,-1.121615886,-1.807885083,-1.563602223,1.422318999,1.371617045,-12.75686141,-14.76882069,-13.43002761,-12.12079459,-13.01878021,-10.44588395,-6.941189385,-2.532213831 -861,T69H,-0.055628356,0.00255992,0.008900143,0.016494293,-1.664324852,-0.006280896,-0.04337642,-0.067880291,-0.049012376,0.018848731,-0.013728891,-0.0000399,0.017840185,0.071385161,-0.038396575,-1.623186968,-1.705462735,0.616871958,1.310989303,-16.43805279,-17.21791068,-15.03825835,-14.16289599,-17.03076466,-18.74043426,-11.19462357,-10.07581263 -862,T69K,-0.04360924,-1.616957607,-2.466101954,-2.241365513,-3.033836619,0.009976759,-0.063254046,-0.023964433,-0.192018643,-1.617659089,-1.616256125,-2.753726042,-2.178477865,-2.490415468,-1.992315558,-2.705982199,-3.361691038,-0.003920767,-1.108293823,-15.38878544,-15.90170132,-14.11138824,-13.64662029,-15.93135444,-17.35286294,-11.18330136,-10.01004175 -863,T69M,-0.022017546,0.055746492,-0.081082689,-1.557463218,-2.478653607,-0.058426799,0.019480575,-0.063515666,-0.026086929,0.053433396,0.058059587,-0.149018517,-0.013146861,-1.432981128,-1.681945308,-2.079911622,-2.877395591,2.719901033,1.768657776,-13.0696115,-14.89475561,-14.13879868,-10.62448895,-14.78542579,-10.90458846,-6.639107642,-2.798218868 -864,T69L,-0.062853535,0.038659222,-0.161206981,-1.68770447,-2.392749482,-0.049850517,-0.040785906,-0.084921164,-0.021045629,0.027796179,0.049522265,-0.183758892,-0.13865507,-1.46384512,-1.91156382,-2.402515534,-2.38298343,1.231737466,0.771520708,-14.17809166,-16.31392998,-14.5168845,-12.60187893,-15.85725185,-11.60051302,-6.458622693,-1.683743159 -865,T69N,-0.042633742,-0.084298081,-1.402418029,-2.11060822,-2.71262599,0.037148493,-0.024070145,-0.061197339,-0.035489925,-0.062919052,-0.105677109,-1.245160886,-1.559675171,-2.061031559,-2.16018488,-2.87865828,-2.546593699,2.337664127,0.885571363,-13.67277468,-14.63774023,-12.26824422,-11.90709372,-14.11666958,-15.43412566,-9.62260525,-6.445616419 -866,T69Q,-0.099424646,-0.306594118,-1.756024139,-2.474744745,-2.361851281,-0.006098008,-0.065012231,-0.133837061,0.061014524,-0.184567176,-0.42862106,-1.583267734,-1.928780544,-2.797078416,-2.152411073,-2.167547106,-2.556155455,1.051096023,0.049428968,-15.16915362,-15.73637352,-13.47614728,-14.12555421,-16.12446354,-16.38322957,-10.2751351,-7.517902377 -867,T69P,-0.042198164,0.032175134,0.042512889,-1.217490587,-2.295937358,-0.004651626,-0.02627112,-0.058125208,-0.001747392,0.037364278,0.02698599,0.045147605,0.039878172,-0.787598797,-1.647382376,-1.949290146,-2.64258457,2.018297907,1.492778807,-14.32250157,-14.69958135,-13.23689788,-13.66708883,-14.95941074,-15.04952905,-9.697991999,-7.216217732 -868,T69S,-0.050313877,0.036361528,0.004310094,-0.013557221,-1.840638186,0.023486387,-0.043229864,-0.05739789,-0.012397323,0.04717323,0.025549825,0.001392062,0.007228125,0.009010725,-0.036125166,-1.493955098,-2.187321274,0.586450482,1.31512768,-5.651851439,-5.665791283,-5.252498199,-4.072699562,-5.423524651,-7.8447435,-5.994508123,-2.757425807 -869,T69R,-0.033826686,-1.568010718,-1.847191764,-2.254073743,-3.293900361,0.055970303,-0.024817536,-0.042835835,-0.187810658,-1.598592377,-1.537429058,-1.78421811,-1.910165417,-2.324612891,-2.183534594,-3.280542311,-3.30725841,3.238418673,0.783433601,-16.32842711,-17.09460003,-14.5526664,-15.23368475,-16.76773276,-17.99345162,-11.19462357,-10.07581263 -870,T69W,-0.103162162,-1.423117082,-2.231793714,-2.278486148,-3.047111258,0.0207619,-0.070104775,-0.136219549,-0.123547929,-1.47615545,-1.370078713,-2.612222404,-1.851365024,-2.34891183,-2.208060465,-2.865508556,-3.22871396,-0.032727358,-1.023125062,-18.16164438,-19.09954415,-18.25193217,-15.66859653,-19.02078509,-18.76736397,-11.19462357,-10.07581263 -871,T69V,-0.061436789,-0.003162264,-0.106787444,-1.5211143,-2.701354223,-0.03538301,-0.056362498,-0.06651108,-0.012605493,0.000704102,-0.00702863,-0.140215354,-0.073359533,-1.35524768,-1.68698092,-2.275944723,-3.126763722,1.202639397,0.785648148,-8.008597308,-9.979805054,-6.967821854,-8.193730782,-8.962129936,-5.939498917,-6.750349907,-0.717806545 -872,T69Y,-0.068609044,-1.469756981,-2.004737793,-2.160560308,-2.899078715,-0.005256922,-0.028609693,-0.108608395,-0.150470713,-1.407109348,-1.532404614,-2.274330989,-1.735144597,-2.011020415,-2.310100201,-2.7037084,-3.09444903,0.622293826,-0.846502567,-18.55613394,-19.74169462,-18.81442363,-14.95372202,-19.39108913,-19.87974029,-11.19462357,-10.07581263 -873,F70A,-0.004612186,0.050537893,0.029291499,0.074641108,-0.061250842,-0.122878254,-0.02403507,0.014810698,-0.021020963,0.00415596,0.096919826,0.034028412,0.024554586,0.072297911,0.076984305,-0.088218805,-0.034282879,1.387359433,2.47471627,-9.085916505,-7.859765274,-9.250729683,-11.84438702,-8.687853409,-7.786847137,-5.254639149,-2.937827005 -874,F70C,-0.05416316,0.027466432,-0.029290388,0.045303396,-0.992654766,0.110081859,-0.03895902,-0.069367299,-0.031885913,-0.010532227,0.065465091,-0.025805582,-0.032775194,0.038891375,0.051715416,-0.794986248,-1.190323284,0.633462878,1.368040107,-9.70662379,-11.02000046,-9.140832565,-10.93694382,-8.813599709,-8.621742393,-6.606571372,-4.25882626 -875,F70E,-0.056775489,0.040870582,-1.310980437,-2.169551935,-2.512372906,-0.042740381,-0.03646489,-0.077086087,-0.065977177,0.105449582,-0.023708419,-1.24202729,-1.379933583,-1.934925168,-2.404178702,-2.790563907,-2.234181904,2.486566607,1.047905239,-14.71197794,-14.73395009,-13.0980824,-18.06336001,-14.98381199,-12.68068523,-9.729586578,-9.655179711 -876,F70D,-0.057271543,-0.79174894,-2.069277197,-1.796583601,-3.155445205,-0.047648491,-0.036093474,-0.078449612,0.033154694,-0.57545041,-1.008047469,-1.736851801,-2.401702592,-1.628117334,-1.965049868,-2.784786068,-3.526104342,3.443525632,1.668194435,-14.55522802,-13.30727068,-12.3451476,-18.45786868,-15.05070731,-13.61514585,-9.729586578,-9.655179711 -877,F70G,-0.032721237,0.042847095,0.037789718,0.083010457,-1.44172006,0.028137942,-0.02689957,-0.038542903,-0.075631217,0.041485304,0.044208885,0.047634816,0.02794462,0.095280264,0.07074065,-1.238525322,-1.644914797,0.633673665,1.3307198,-10.46870049,-11.74912482,-10.64335997,-10.55234083,-11.06647808,-8.332198769,-5.497358964,-4.427234418 -878,F70I,-0.034587296,0.062999802,0.095319636,0.090225895,-1.374392405,0.056843968,-0.028542438,-0.040632153,-0.112185149,0.057008267,0.068991336,0.090517472,0.100121799,0.103582009,0.076869781,-1.409714466,-1.339070344,0.681860812,1.323460689,-9.897836623,-9.229908813,-9.516233757,-12.49029485,-10.20848219,-8.044263504,-5.100540272,-0.555050924 -879,F70H,0.052365187,-0.05468426,-0.061522744,0.0000876,-0.361345687,-0.125992294,0.00493905,0.099791324,-0.088021287,-0.021398145,-0.087970375,-0.00714718,-0.115898307,-0.058743424,0.05891866,-0.296235351,-0.426456022,1.622583925,2.154389735,-5.177227145,-6.854817268,-3.393710396,-7.376575485,-4.994983261,-3.266049316,-4.32094502,-2.801544561 -880,F70K,-0.091747294,0.013684257,-1.700638835,-1.999487353,-2.791579503,0.132760471,-0.056071797,-0.12742279,0.078824803,0.036379177,-0.009010664,-1.827512865,-1.573764805,-1.968655871,-2.030318834,-2.222234618,-3.360924387,0.344071183,-0.05179231,-14.57501632,-16.00471822,-12.35072334,-17.20598676,-14.2863196,-13.02733366,-9.712055115,-9.558831591 -881,F70M,-0.049603174,0.008343828,0.008021333,-0.00483853,0.011483928,0.015716142,-0.037810748,-0.0613956,-0.144008633,0.036276567,-0.019588912,0.05604596,-0.040003294,-0.033090605,0.023413546,0.056879904,-0.033912048,1.136844583,2.732551063,-10.55950328,-9.253477478,-10.81630177,-12.77338423,-12.02794076,-7.92641214,-5.740083923,-2.077452877 -882,F70L,-0.097846925,0.009572438,0.009863398,-0.012687782,-1.86560969,0.005219128,-0.078180837,-0.117513013,-0.066113898,-0.000824729,0.019969604,0.01198491,0.007741886,-0.002924888,-0.022450676,-1.533644555,-2.197574824,0.576926284,1.311734016,-9.765265729,-8.497757942,-10.05480292,-11.72309382,-11.64063809,-6.910035873,-6.251001637,-4.088613192 -883,F70N,-0.143738536,0.024498221,-0.041049122,-0.089691947,-1.799938512,0.02704759,-0.127806358,-0.159670714,-0.080121026,0.01768104,0.031315402,0.020291068,-0.102389311,-0.011379327,-0.168004566,-1.939688028,-1.660188996,0.589376528,1.297059672,-11.74370806,-12.07736552,-9.340758568,-14.58510719,-12.48960138,-10.22570766,-6.907242301,-3.71449954 -884,F70Q,-0.026713535,0.008806688,0.033625177,-0.073435539,-2.230348399,0.044918568,-0.027686872,-0.025740198,-0.036549313,-0.006957766,0.024571142,0.03689033,0.030360024,-0.03457497,-0.112296108,-1.67222538,-2.788471417,0.703846259,1.313580535,-13.44462861,-12.29040967,-12.13622935,-17.43158511,-14.40741529,-10.95750362,-9.729586578,-9.655179711 -885,F70P,-0.031946444,-1.352776447,-1.83103648,-2.212578135,-2.965079662,0.027865192,-0.015926344,-0.047966544,-0.057243629,-1.326867929,-1.378684965,-1.76035145,-1.901721509,-2.1189784,-2.30617787,-2.372557147,-3.557602177,3.858127207,1.652147849,-14.70290575,-14.9444729,-13.71003355,-17.34600766,-14.61092152,-12.9030931,-9.729586578,-9.655179711 -886,F70S,-0.04805045,0.008869864,0.005711616,0.026640993,-0.364725872,-0.007689261,-0.044295339,-0.051805561,-0.027173334,-0.007830619,0.025570346,-0.009098435,0.020521667,0.01015483,0.043127155,-0.283429078,-0.446022665,1.440751537,2.037717133,-7.657532199,-8.193356308,-6.924604279,-8.963448715,-5.77989608,-8.426355614,-4.916078079,-2.176951169 -887,F70R,-0.056427094,-0.24058132,-1.886324896,-1.970961728,-2.691720127,0.068760954,-0.038544672,-0.074309516,-0.04613557,-0.179383879,-0.30177876,-2.04776093,-1.724888862,-2.001817292,-1.940106164,-2.732517294,-2.650922959,0.692000599,-0.187892002,-11.52549287,-10.69684155,-9.880773376,-16.26878606,-11.65253188,-9.128531471,-7.594306696,-5.375103476 -888,F70T,-0.078416017,0.03029292,0.011951176,0.021167971,-1.718556765,0.060416741,-0.02801184,-0.128820194,-0.006185274,-0.004083111,0.064668951,-0.032270879,0.05617323,0.038555008,0.003780933,-1.552078064,-1.885035466,0.611611968,1.313289089,-11.62546475,-11.24747609,-10.53097983,-15.09091251,-10.89615591,-10.36179942,-7.065856454,-4.696843524 -889,F70W,0.00234178,0.014628795,-0.008423998,0.011956056,-1.012644172,-0.135875169,-0.007808453,0.012492013,-0.050328684,-0.074185199,0.103442788,-0.039816297,0.022968302,-0.054229658,0.07814177,-0.809753244,-1.2155351,0.959299513,1.437174483,-8.765915517,-8.495728889,-9.498482529,-9.916197746,-8.646312973,-7.272855446,-6.161588706,-4.976823612 -890,F70V,-0.048794004,0.030406711,0.031028741,0.048168094,-0.037759015,0.024964622,-0.066910194,-0.030677813,-0.052155205,0.028973361,0.03184006,0.036760477,0.025297004,0.052799197,0.04353699,-0.012973468,-0.062544561,1.149243679,2.545344641,-8.432587537,-6.875855286,-8.372665451,-10.90948483,-9.235303627,-6.769628494,-4.603356304,-1.567676314 -891,F70Y,0.009889471,0.064875494,0.026559343,-0.039324537,-2.663858905,-0.196552382,0.005555508,0.014223433,-0.0863798,0.046773045,0.082977942,0.073598556,-0.020479871,0.040202272,-0.118851345,-2.138688566,-3.189029243,0.937490681,1.290382178,-4.196971487,-4.12417453,-3.081731812,-5.967478432,-4.058393135,-3.753079529,-3.645805928,-1.643709433 -892,K71A,-0.022341313,-1.389627623,-2.242187535,-2.496077623,-3.5759083,-0.123821227,-0.043061849,-0.001620777,0.018303515,-1.382603084,-1.396652161,-2.426585325,-2.057789744,-2.289194053,-2.702961192,-3.659214581,-3.492602018,0.041069028,-0.868897031,-7.428212964,-7.521384315,-7.329100876,-7.475908577,-7.37615509,-7.438515961,-7.258929054,-6.711949012 -893,K71C,-0.073174879,-1.501789806,-2.40277975,-2.390350547,-3.20302712,0.222347664,-0.040179269,-0.106170488,-0.069123709,-1.60059405,-1.402985562,-2.102812202,-2.702747297,-2.634427711,-2.146273382,-2.858320203,-3.547734037,-0.023154012,-1.027319465,-9.833668469,-9.787034142,-9.912073395,-9.840831795,-9.866564423,-9.761838593,-9.13866872,-11.28944481 -894,K71E,-0.029246166,-1.695551181,-1.948134468,-2.687430361,-2.790542281,-0.059911979,-0.026992081,-0.03150025,-0.13143703,-1.641937749,-1.749164613,-2.303856743,-1.592412192,-2.534442256,-2.840418466,-2.758334749,-2.822749813,0.139259825,-1.059684733,-7.981267249,-7.907765251,-8.226845894,-7.922390648,-8.016172028,-7.833162422,-7.856059275,-7.526033717 -895,K71D,-0.053353874,-1.868649637,-2.446777334,-2.622723486,-3.26990345,-0.099993119,-0.045352673,-0.061355075,-0.185107603,-2.028146904,-1.70915237,-2.354273796,-2.539280872,-2.709798046,-2.535648925,-2.933690538,-3.606116361,-0.061271992,-1.191931139,-9.821797421,-9.742821655,-9.761632843,-9.858717918,-9.942163338,-9.803651352,-9.13866872,-11.28944481 -896,K71G,-0.03267641,-1.741220386,-2.133378725,-2.295687834,-3.385171089,-0.062753908,-0.043356256,-0.021996563,-0.146275538,-1.855477228,-1.626963543,-2.35769538,-1.90906207,-2.220304108,-2.37107156,-2.988264644,-3.782077533,-0.222585842,-1.140412311,-9.797629523,-9.791578461,-9.788956367,-9.84127018,-9.823898354,-9.742444252,-9.13866872,-11.28944481 -897,K71F,-0.068589139,-1.689206737,-2.1161999,-2.4532557,-2.916447271,-0.111640162,-0.062040106,-0.075138172,-0.209574612,-1.640391822,-1.738021652,-2.364458723,-1.867941077,-1.941831723,-2.964679676,-2.64284547,-3.190049072,0.164857191,-1.107999625,-9.786984508,-9.759945221,-9.778404785,-9.660896065,-9.895395844,-9.840280624,-9.13866872,-11.28944481 -898,K71I,-0.01482397,-2.167284589,-2.449879983,-2.335390788,-2.773006099,-0.033942327,0.037021573,-0.066669512,-0.017629088,-2.121805973,-2.212763205,-2.447932866,-2.4518271,-2.201397124,-2.469384452,-2.726319612,-2.819692585,-0.424853017,-1.13637661,-9.816646231,-9.919712357,-9.769868622,-9.803701813,-9.92631575,-9.663632614,-9.13866872,-11.28944481 -899,K71H,0.002468864,-1.932019025,-2.086978165,-2.424033964,-3.227846154,-0.09548181,-0.01031781,0.015255538,-0.146226987,-2.056635442,-1.807402607,-2.030579816,-2.143376514,-2.738286584,-2.109781344,-2.564239067,-3.891453241,-0.116763868,-1.160365058,-9.82200435,-9.784632713,-9.818676369,-9.92590435,-9.805128197,-9.775680122,-9.13039196,-11.20689 -900,K71M,-0.069685438,-1.734598039,-2.241739698,-2.553219236,-3.016410807,-0.130262465,-0.070628751,-0.068742124,-0.191056935,-1.898107472,-1.571088605,-2.099295628,-2.384183767,-2.454819878,-2.651618593,-2.67871237,-3.354109243,-0.064607945,-1.155820113,-8.659729297,-8.644042053,-8.774832283,-8.8217836,-8.585026459,-8.47296209,-8.127854019,-8.205072427 -901,K71L,-0.043237132,-1.799813527,-2.133263369,-2.413967028,-3.12361636,-0.107937245,-0.032342666,-0.054131598,-0.159364962,-1.833508226,-1.766118828,-2.159635119,-2.106891618,-2.566311891,-2.261622164,-2.69329437,-3.553938349,0.022446297,-1.130619268,-9.458673164,-9.272165161,-9.710671478,-9.479141151,-9.47148465,-9.359903381,-8.76208769,-9.284504038 -902,K71N,0.009434887,-1.430114728,-2.280446826,-2.192749045,-2.875606964,-0.105943152,-0.004832194,0.023701968,-0.081358165,-1.61268255,-1.247546906,-2.592021956,-1.968871695,-2.169394956,-2.216103134,-2.870408703,-2.880805224,-0.194370888,-1.07199181,-9.732415509,-9.611261948,-9.731493301,-9.841481155,-9.878447891,-9.59939325,-9.130668229,-11.25349789 -903,K71Q,-0.039866595,-1.815924491,-2.730140602,-2.439560149,-3.053266718,-0.091015009,-0.036805781,-0.042927409,-0.163856803,-1.677580777,-1.954268205,-2.702677674,-2.75760353,-2.456141933,-2.422978365,-2.98106442,-3.125469015,-0.071627646,-1.111363545,-8.445954745,-8.241887138,-8.629492958,-8.43746653,-8.492394394,-8.428532707,-8.157069101,-7.997069885 -904,K71P,-0.05435827,-1.766763767,-2.103727406,-2.365779742,-3.122786452,0.016499536,-0.0426467,-0.06606984,-0.141233902,-1.799285038,-1.734242496,-2.203572508,-2.003882303,-2.240093391,-2.491466093,-2.953006361,-3.292566542,-0.334093518,-1.144157337,-9.810337883,-9.853272964,-9.80120916,-9.720756645,-9.853996841,-9.822453804,-9.13866872,-11.28944481 -905,K71S,-0.018584415,-1.571905657,-2.123506915,-2.409903148,-3.743276064,-0.067771768,-0.02312009,-0.01404874,-0.067361863,-1.605658767,-1.538152547,-2.304171563,-1.942842267,-2.504793853,-2.315012443,-3.42765635,-4.058895778,-0.167303383,-1.041359732,-7.956372313,-7.867123444,-7.926501854,-7.965756332,-8.003749275,-8.018730659,-7.75790133,-7.526033691 -906,K71R,-0.074437132,-1.389014437,-2.094399992,-2.26112359,-3.181662996,-0.021993553,-0.072697411,-0.076176853,-0.121209195,-1.32484997,-1.453178904,-2.119980227,-2.068819756,-2.199298065,-2.322949114,-2.750549492,-3.612776499,2.654953805,0.282574448,-7.487875397,-7.428443611,-7.592430008,-7.420646393,-7.530441208,-7.467415764,-7.584818132,-7.081301237 -907,K71T,-0.026357297,-1.642889659,-2.043785169,-2.301659722,-3.017426283,-0.083998593,-0.013035879,-0.039678715,-0.101592363,-1.71301623,-1.572763087,-1.955597071,-2.131973267,-2.010091325,-2.593228119,-2.535013813,-3.499838752,0.117603553,-1.046041142,-6.777715538,-6.723575241,-6.830490097,-6.893051781,-6.731180412,-6.710280159,-6.894332614,-6.444839652 -908,K71W,-0.003949216,-1.607717082,-2.110874276,-2.47412411,-2.906241728,-0.048581541,0.02034402,-0.028242451,-0.131679213,-1.665534857,-1.549899306,-2.343844268,-1.877904284,-2.699368518,-2.248879701,-2.92326101,-2.889222445,-0.170433277,-1.103846406,-9.808292342,-9.785322731,-9.757114311,-9.850292557,-9.874991295,-9.773740814,-9.13866872,-11.28944481 -909,K71V,-0.017826069,-1.626137383,-2.300684566,-2.646604749,-3.260311318,-0.109732287,-0.002144818,-0.03350732,-0.046109345,-1.683720536,-1.56855423,-2.510449779,-2.090919353,-2.440005297,-2.8532042,-2.663897789,-3.856724847,-0.387166724,-1.08008484,-8.73108681,-8.621626999,-8.831675255,-8.730385429,-8.836264099,-8.635482269,-8.489117626,-8.620431725 -910,K71Y,-0.060175188,-2.0340453,-2.500629086,-2.837684885,-3.062315829,-0.094350034,-0.029031384,-0.091318991,-0.16761011,-2.151610955,-1.916479645,-2.477737847,-2.523520324,-2.532232102,-3.143137668,-2.756124594,-3.368507064,-0.268920477,-1.200743881,-8.729243103,-8.576681099,-8.748501457,-8.913617149,-8.87844381,-8.528972,-8.559992384,-8.219598506 -911,V72A,-0.027805008,-0.015065753,-0.00369984,-0.042274095,-0.856415618,0.059839813,-0.025553333,-0.030056682,0.026489985,-0.027162261,-0.002969245,0.017834445,-0.025234125,-0.031889358,-0.052658831,-0.550051544,-1.162779691,0.834882461,1.46460614,-2.960336475,-1.828372192,-2.903871048,-2.311072868,-3.538372147,-4.219994118,-3.155021867,-0.432795055 -912,V72C,-0.024673567,0.026718226,0.015369262,-0.058745162,-1.496115302,0.056638112,-0.036696621,-0.012650513,-0.006530867,-0.013378896,0.066815348,0.009053057,0.021685467,-0.06154074,-0.055949583,-1.452333778,-1.539896825,0.823601845,1.335695021,-10.09612404,-9.851898949,-8.774846085,-10.73412229,-9.553087067,-11.56666579,-7.795746162,-5.623380455 -913,V72E,-0.227202028,-0.420793402,-1.371331423,-1.497348107,-1.725521981,0.418339938,-0.088093446,-0.36631061,-0.281879642,-0.101826927,-0.739759876,-1.02678006,-1.715882785,-1.110982107,-1.883714106,-1.309765553,-2.141278408,4.016502244,3.16702012,-10.67133559,-10.18014629,-8.616279869,-10.79678746,-10.51672675,-13.24673757,-9.357759314,-6.734369282 -914,V72D,-0.019572925,-1.671150908,-2.207037043,-2.211534702,-2.711742599,0.052141238,-0.007678963,-0.031466886,-0.054383993,-1.579723016,-1.7625788,-2.152493631,-2.261580454,-2.060604419,-2.362464985,-2.73650912,-2.686976077,-0.21665399,-1.02881017,-12.12908635,-11.55562926,-10.06414733,-12.5110807,-11.59871064,-14.91586384,-10.1347644,-9.125508624 -915,V72G,-0.030763273,-0.005612139,-0.205865066,-1.828756692,-2.575720423,0.058110992,-0.017503526,-0.04402302,-0.051147686,-0.022759504,0.011535226,-0.197324569,-0.214405562,-1.571030629,-2.086482755,-2.489973378,-2.661467468,1.335659485,0.763442169,-9.329563174,-9.275374893,-7.726531921,-9.360203484,-8.937884239,-11.34782133,-5.852522545,-2.539726214 -916,V72F,0.001824488,-0.011163712,-0.267079934,-1.475531555,-2.583539351,0.023247317,0.038481053,-0.034832078,0.095796151,-0.004362613,-0.01796481,-0.20738742,-0.326772448,-1.506433316,-1.444629793,-2.404186766,-2.762891935,1.269366205,0.775656037,-9.344027129,-8.169963165,-6.637502655,-12.31546964,-6.7687313,-12.82846889,-5.940527977,-0.874126842 -917,V72I,0.028744624,-0.024292395,-0.103479614,0.022198371,-0.507858731,0.020444089,0.027932857,0.02955639,-0.074637816,-0.110457259,0.06187247,-0.095767391,-0.111191837,-0.017706379,0.062103121,-0.343135025,-0.672582436,1.394439741,1.904356899,-5.342679185,-6.329724457,-4.718560226,-5.376194122,-5.984338791,-4.304578331,-6.560786592,-0.82323682 -918,V72H,-0.087132349,0.003906718,-1.058058409,-2.225542541,-2.692277041,0.006191825,-0.078674724,-0.095589974,-0.031509414,0.018055938,-0.010242502,-0.721996415,-1.394120402,-2.248155301,-2.20292978,-2.623030005,-2.761524077,1.668212387,0.62249857,-12.57578015,-11.19113375,-9.099641022,-14.76982511,-11.45620301,-16.36209788,-9.37860367,-7.314857802 -919,V72K,-0.380364117,-1.317882749,-1.291299516,-1.4173162,-1.645490074,0.195761894,-0.369435335,-0.391292898,-0.102959092,-0.813031387,-1.822734111,-0.783742011,-1.79885702,-0.867944059,-1.966688341,-1.066727504,-2.224252643,3.623108256,3.069597641,-11.62049921,-11.93941446,-8.963326172,-11.6359828,-11.19290874,-14.37086386,-10.1347644,-9.125508622 -920,V72M,0.05653194,-0.055579535,0.078278454,-1.513848237,-1.892537109,0.108476529,0.035253495,0.077810385,-0.068448241,-0.101826927,-0.009332143,0.134587942,0.021968966,-1.110982107,-1.916714366,-1.610795549,-2.174278668,3.017006997,2.308211273,-7.378028198,-7.54708046,-6.2715923,-8.296027061,-6.007042953,-8.768398216,-5.592804947,-2.672319864 -921,V72L,0.003981852,0.040422773,0.017088116,-0.338428524,-1.964738695,0.01399516,0.011487566,-0.003523862,-0.032616707,-0.004403866,0.085249411,0.010286001,0.023890231,-0.201585423,-0.475271625,-1.62488201,-2.304595379,1.210821138,1.363598483,-5.281452625,-5.695308762,-5.22336718,-7.091591789,-2.833224014,-5.563771378,-5.342466635,-0.001593514 -922,V72N,-0.06523045,-0.689742614,-1.608409811,-1.918414887,-2.686179384,-0.023621601,-0.047693434,-0.082767466,0.035343606,-0.560306071,-0.819179157,-2.062495612,-1.154324009,-1.845667664,-1.99116211,-2.345481105,-3.026877662,1.265894446,-0.195496007,-12.11868162,-12.17686385,-10.61537549,-12.70920545,-11.06998328,-14.02198003,-10.1347644,-9.125508619 -923,V72Q,0.08921719,-0.211847986,-1.602352789,-2.134826151,-2.513515023,0.125755566,0.124290885,0.054143494,-0.069440915,-0.28155247,-0.142143502,-1.95983327,-1.244872307,-1.743005322,-2.52664698,-2.242818763,-2.784211282,3.99561871,2.199436798,-10.73527726,-10.52604308,-9.272590675,-10.38185872,-10.21199604,-13.28389776,-8.920950041,-6.736501291 -924,V72P,0.031310514,0.010357175,0.022961709,-0.003403723,-0.027108305,-0.044071322,0.003343027,0.059278001,0.004056785,-0.024078678,0.044793027,0.01989516,0.026028258,-0.024468275,0.01766083,-0.031011952,-0.023204657,1.319255397,2.515870088,-5.957245757,-5.868305099,-4.896244392,-6.102723,-4.982215675,-7.936740616,-4.776044599,-3.079748695 -925,V72S,-0.022299348,-0.010718031,-0.003748603,-0.021408331,-1.456171302,0.013080475,-0.037460104,-0.007138591,-0.059600197,-0.049136424,0.027700363,-0.027279536,0.019782331,-0.000121604,-0.042695057,-1.374223542,-1.538119062,0.741602641,1.332392611,-6.394013899,-5.999102623,-6.190459328,-6.674850014,-5.454113899,-7.651543633,-5.112541195,-3.299132032 -926,V72R,-0.041560241,-1.425340606,-1.985458433,-2.195536282,-2.923710155,0.069975753,-0.056358152,-0.02676233,-0.19734413,-1.481700852,-1.368980359,-2.035988062,-1.934928803,-1.89834136,-2.492731203,-3.097124805,-2.750295505,-0.349871067,-1.102522968,-11.83603248,-11.41886273,-10.46571928,-11.66217704,-11.13658121,-14.49682213,-10.1347644,-9.125508613 -927,V72T,0.026549943,0.024497295,-0.01619889,-0.0032849,-0.315691669,-0.013390216,0.019502638,0.033597247,0.014809948,-0.010573648,0.059568238,-0.020976098,-0.011421682,-0.016661145,0.010091346,-0.229930741,-0.401452597,1.186718344,1.900478504,-3.799587802,-5.66988588,-2.409797752,-3.104544868,-2.929609131,-4.884101379,-5.368511167,-1.063179863 -928,V72W,-0.091458333,-0.54702568,-1.65047814,-1.776494825,-2.004668698,0.071646465,0.002669673,-0.185586338,0.006185377,-0.479816708,-0.614234651,-1.295625372,-2.005330908,-1.37982742,-2.173162229,-1.578610865,-2.430726531,4.260887365,2.95946835,-10.12354835,-7.398599464,-8.432560318,-10.76323904,-9.454985306,-14.56835764,-5.930063173,-2.985370733 -929,V72Y,-0.010121409,-0.759473762,-2.009346254,-1.794742319,-2.713021813,0.049150617,0.02083588,-0.041078698,0.159637271,-0.49451066,-1.024436864,-2.04500488,-1.973687627,-1.828176932,-1.761307706,-2.327990373,-3.098053253,1.172456933,-0.17504751,-11.95632267,-10.69564837,-7.831805557,-13.96516068,-9.76371904,-17.52527969,-7.384904256,-3.630981347 -930,L73A,-0.00747685,0.001386862,-0.000839058,0.023179191,-0.064115567,-0.002177337,-0.003849952,-0.011103747,0.030879958,0.018690144,-0.01591642,-0.000717487,-0.000960628,0.030107199,0.016251182,-0.029505436,-0.098725698,1.100080585,2.476287868,-6.303990211,-5.55218396,-9.067375923,-5.373495941,-7.211072891,-4.315822342,-4.93892351,-1.47830732 -931,L73C,0.015880851,0.009399786,0.069407413,0.089836702,-0.724250974,0.080759772,0.007424852,0.024336849,0.020648324,-0.054199286,0.072998858,0.025935734,0.112879091,0.031590734,0.148082669,-0.548720807,-0.89978114,0.636938905,1.409077946,-9.659955618,-7.797995674,-11.35941367,-10.11229609,-9.99761972,-9.032452934,-7.381751486,-4.118376786 -932,L73E,-0.032193585,-0.02060762,-0.454042627,-1.793204936,-2.947544269,0.03620599,-0.013067835,-0.051319334,-0.013497172,-0.064314694,0.023099454,-0.224795628,-0.683289625,-1.458274036,-2.128135836,-2.363855623,-3.531232914,1.42695384,0.820807066,-10.93263555,-9.551456619,-12.55317657,-10.83326192,-11.67215127,-10.05313135,-8.409953719,-6.817490654 -933,L73D,-0.007161325,-0.037572552,-0.059480888,-1.752410167,-2.994795129,0.044371156,0.019355712,-0.033678362,0.078371161,-0.041122399,-0.034022704,-0.084157264,-0.034804512,-1.276981584,-2.227838749,-2.659684425,-3.329905832,0.947747434,0.750002065,-12.32247162,-11.9773491,-13.23842351,-11.81318225,-13.01174426,-11.57165899,-9.327380676,-9.145311157 -934,L73G,-0.022910036,0.003078483,0.00474493,0.015357064,-1.463946668,0.117438263,-0.007003873,-0.038816198,-0.013563792,0.024383346,-0.018226381,0.013659776,-0.004169916,0.021860716,0.008853411,-1.365790123,-1.562103213,0.525396585,1.318414269,-10.33413128,-9.471213104,-12.52527628,-10.27609064,-11.18234621,-8.215730156,-6.109087168,-3.937370725 -935,L73F,-0.051340173,-0.038060907,0.010240302,-0.053278238,-0.448223556,0.057962545,-0.047264886,-0.05541546,0.01857118,-0.044439449,-0.031682364,0.04709539,-0.026614786,-0.089058179,-0.017498296,-0.320493345,-0.575953766,1.235423376,1.801920909,-3.997847171,-3.114886307,-5.317045944,-4.878346878,-2.472757217,-4.206199509,-3.684623168,-1.369137634 -936,L73I,0.013393716,-0.021910424,0.005183018,-0.002772592,0.028685084,-0.011751602,0.015317944,0.011469488,0.059829714,-0.075457614,0.031636766,-0.044601214,0.05496725,-0.074734851,0.069189668,-0.059166288,0.116536455,1.518711882,2.566872107,-3.863398647,-3.359509262,-3.370143662,-4.023543053,-4.937362923,-3.626434334,-3.637685438,-2.366266146 -937,L73H,-0.038784991,-0.054103331,-0.041802456,0.0051662,-1.573675901,0.11313851,-0.000314657,-0.077255325,0.037660522,-0.022373672,-0.08583299,-0.084996899,0.001391987,0.011999215,-0.001666815,-1.480004994,-1.667346807,0.652300835,1.317587297,-8.057636627,-6.17494558,-8.629783653,-9.025859192,-6.544224167,-9.913370544,-5.798620596,-1.613499987 -938,L73K,-0.010680711,-0.650762396,-1.682049234,-1.979532786,-2.943766498,0.021996302,0.020655767,-0.042017188,-0.037517703,-0.562328953,-0.739195839,-1.559326499,-1.804771969,-2.074949559,-1.884116013,-2.883621133,-3.003911863,2.773865428,1.024208257,-10.90491996,-10.24283763,-11.93158435,-10.82577906,-10.87014426,-10.65425448,-9.309240749,-9.05312673 -939,L73M,0.026361935,0.015778941,0.005162353,0.013937103,-0.10406419,0.015761255,0.038722976,0.014000894,-0.028106126,-0.003076427,0.034634308,-0.01479723,0.025121935,0.001616667,0.026257538,-0.108503365,-0.099625014,1.463557431,2.383202407,-3.894953603,-4.028867981,-4.46126902,-3.097025299,-4.819400284,-3.068205429,-3.674655188,-2.165927519 -940,L73N,-0.012146497,0.016128115,-0.011162275,-0.451238733,-2.274293433,0.082436202,0.005885708,-0.030178701,0.064841602,0.007663669,0.02459256,-0.007031764,-0.015292785,-0.271380456,-0.631097009,-2.017068137,-2.531518728,1.326564825,1.329883788,-11.57814435,-10.78497028,-12.560299,-11.80791635,-11.84512508,-10.89241103,-9.327380676,-9.14531113 -941,L73Q,0.017952194,0.050132984,0.053726691,-0.56246493,-1.509534628,0.10094127,0.067236906,-0.031332519,-0.029180005,0.088324625,0.011941343,0.042657294,0.064796087,-0.219462284,-0.905467576,-1.496481189,-1.522588067,1.22819738,1.379497999,-7.777840666,-8.062043747,-8.887946968,-6.881660103,-6.950113655,-8.107438858,-6.069517201,-4.620560756 -942,L73P,0.004343286,-0.007240375,-0.000636882,0.022476496,-0.134780892,0.015944083,0.017822153,-0.009135582,0.033989984,0.003604476,-0.018085226,-0.000331712,-0.000942052,0.033765008,0.011187984,-0.093665329,-0.175896455,1.372413649,2.351118676,-3.107943782,-2.07627179,-6.213701279,-1.419697609,-3.872377235,-1.957670998,-3.12040644,0.35962014 -943,L73S,0.000995064,0.001674422,0.046240691,0.029119437,-0.986445615,0.091674709,0.033719725,-0.031729598,0.001258126,0.001703358,0.001645485,0.041780648,0.050700733,0.037246265,0.020992609,-0.782957575,-1.189933655,0.630413013,1.369631712,-7.140405714,-6.049184677,-9.566310616,-7.06583152,-8.120005737,-4.900696022,-4.94164279,-2.414115749 -944,L73R,-0.031299565,-1.411498419,-1.791456507,-1.787333252,-2.580447035,0.079332082,-0.006559111,-0.056040018,-0.065605944,-1.373785609,-1.449211228,-1.624879506,-1.958033508,-1.676346288,-1.898320215,-2.12271821,-3.038175859,4.197562441,2.137672549,-11.73544042,-12.92135189,-12.52713348,-10.42446619,-10.86356042,-11.94069012,-9.327380676,-9.145311135 -945,L73T,-0.02059384,-0.02210319,-0.037882938,-0.003443189,-0.755295224,0.076290883,-0.012505761,-0.028681918,0.04430232,0.012275161,-0.05648154,-0.044886673,-0.030879202,-0.036322396,0.029436018,-0.589676411,-0.920914036,0.84076467,1.454027147,-8.12943324,-7.247911446,-10.16799795,-8.10525322,-9.482163506,-5.64384008,-6.498701822,-4.111969465 -946,L73W,-0.083856435,-0.057215124,-0.274073955,-1.775131512,-2.32208182,0.053937089,-0.058459827,-0.109253043,-0.028436818,-0.044564804,-0.069865443,-0.23640747,-0.311740439,-1.369547472,-2.180715551,-2.3358269,-2.308336739,1.096195878,0.752934832,-8.195167238,-8.506304207,-8.69108477,-9.116256325,-6.167587715,-8.494603172,-6.258601733,-2.364015528 -947,L73V,0.010649922,-0.000662605,0.01066079,0.017592247,-0.036333311,0.024543491,0.040681197,-0.019381354,0.100936773,-0.001732438,0.000407228,0.035228803,-0.013907224,-0.016892077,0.052076571,-0.003946707,-0.068719915,1.338798161,2.641950211,-3.665205779,-3.541421997,-3.576102715,-3.155475105,-4.973662476,-3.0793666,-3.220299495,-2.029691838 -948,L73Y,-0.022241227,-0.010332269,-0.018572859,0.030946308,-1.787903299,0.053528957,-0.010439844,-0.034042609,-0.078881971,-0.042480713,0.021816176,-0.006537321,-0.030608397,0.018559193,0.043333422,-1.49313493,-2.082671668,0.565240506,1.314980287,-7.51703033,-5.350079979,-9.510669144,-8.141713669,-5.900639427,-8.682049431,-5.260362777,-2.205373118 -949,L74A,-0.026083739,0.029978357,0.000919232,0.013125424,-1.314976379,0.090138337,-0.01440433,-0.037763147,0.068370891,0.067783326,-0.007826613,0.045364936,-0.043526472,0.049041384,-0.022790536,-1.087167017,-1.54278574,0.486114534,1.327736209,-3.693407797,-4.260184441,-3.815043137,-3.915535469,-2.08899865,-4.38727729,-3.043868436,-0.151715725 -950,L74C,-0.046976283,0.000278301,0.048074756,-0.264412536,-2.220898794,0.061852821,-0.015426833,-0.078525733,0.040366661,0.008257166,-0.007700564,0.05752902,0.038620492,-0.126914694,-0.401910378,-1.744773692,-2.697023895,1.070334307,1.33552647,-10.43577897,-12.26280608,-10.29591154,-11.49155151,-8.510739334,-9.617886421,-7.390717888,-5.760507144 -951,L74E,-0.015613064,-0.037314174,-0.013733456,-1.03588883,-2.636127763,0.116817184,0.010121467,-0.041347594,0.090483692,-0.051749323,-0.022879024,-0.034638888,0.007171976,-0.732285954,-1.339491706,-2.587327256,-2.68492827,1.115791921,0.906526154,-11.51939574,-12.73613544,-10.84682243,-12.51947208,-11.00838402,-10.48616471,-6.964032763,-5.352190644 -952,L74D,-0.071073908,-1.231197676,-1.610407898,-1.717094718,-2.735655563,0.060193665,-0.080213897,-0.061933918,-0.130051546,-1.28733037,-1.175064982,-1.818929208,-1.401886588,-1.94425147,-1.489937965,-2.56884385,-2.902467275,4.02536965,1.84501417,-13.86264142,-15.31346387,-13.81455099,-15.13405254,-11.86965215,-13.18148756,-9.359036783,-9.351993138 -953,L74G,-0.012887098,0.02541357,-0.752166151,-1.799200861,-2.386275324,0.097013027,0.004027392,-0.029801587,-0.046239639,0.060824659,-0.00999752,-0.525185283,-0.979147018,-1.670970599,-1.927431122,-2.398225322,-2.374325326,1.882408328,0.926208271,-10.94658524,-13.51870602,-11.32702902,-11.08519626,-8.49701841,-10.30497649,-6.250203836,-4.114544375 -954,L74F,-0.036409891,-1.238173072,-1.930240566,-2.450469263,-3.112424886,0.107999068,0.01046337,-0.083283152,-0.032328139,-1.120579137,-1.355767006,-2.12929923,-1.731181901,-1.999348987,-2.901589538,-3.004152609,-3.220697163,0.458370377,-0.680525515,-11.61816316,-12.54386303,-10.86236402,-12.64528864,-11.15732284,-10.88197727,-9.316485112,-9.055397934 -955,L74I,0.000292831,0.05686352,0.034120258,0.033440691,-1.473556368,0.007313962,0.018889151,-0.018303489,0.092201011,0.064989998,0.048737042,0.061521413,0.006719103,0.081132429,-0.014251047,-0.890846052,-2.056266684,0.554346207,1.346901222,-4.407162672,-6.011362625,-3.006721886,-4.443121979,-4.380247215,-4.194359657,-4.76524526,0.075602475 -956,L74H,-0.048783512,-1.050894421,-2.213600792,-2.387818916,-3.487305171,0.100084974,0.033260722,-0.130827746,0.068013912,-0.98865428,-1.113134561,-2.326433092,-2.100768491,-2.372574108,-2.403063724,-3.076347734,-3.898262608,0.236206856,-0.646385682,-15.06440324,-14.64071146,-15.18742181,-16.76523162,-13.73744101,-14.9912103,-9.359036783,-9.35199292 -957,L74K,-0.052036885,-1.137728428,-1.854171567,-2.182748103,-3.106143099,0.081099724,-0.012510111,-0.091563659,0.138899749,-1.188843969,-1.086612886,-1.975715312,-1.732627821,-2.498977583,-1.866518623,-2.725629954,-3.486656244,-0.145738786,-0.730169036,-14.18143313,-15.03937639,-14.74704433,-14.73900453,-12.29664819,-14.08509222,-9.359036783,-9.351993018 -958,L74M,0.03852772,0.018414876,0.039793984,0.019934201,-0.428434117,0.019642165,0.059301875,0.017753565,-0.003559497,0.056668699,-0.019838947,0.006911754,0.072676213,0.031889457,0.007978944,-0.29105058,-0.565817653,1.365583927,1.96527427,-6.142061215,-6.875581429,-6.333085304,-5.72943277,-5.844398033,-5.92780854,-5.610253161,-3.690664326 -959,L74N,-0.023085612,-0.152651943,-1.302903354,-1.67389584,-2.872405012,0.057480679,-0.001170295,-0.045000929,-0.013200379,-0.087779278,-0.217524607,-1.488609836,-1.117196871,-2.011872107,-1.335919572,-2.539554474,-3.20525555,2.223362145,0.694219574,-12.30180972,-14.11656486,-12.02350327,-13.26573183,-10.66662369,-11.43662498,-6.922977781,-5.062897311 -960,L74Q,-0.060332145,-0.082856653,-0.598944631,-2.103866252,-3.24294313,0.152911997,0.006017429,-0.126681719,-0.009463001,-0.083989323,-0.081723983,-0.403022395,-0.794866867,-1.40340592,-2.804326583,-2.885330797,-3.600555463,1.707220454,0.927811872,-10.64060712,-11.64856188,-10.78763092,-11.64161214,-9.274302895,-9.85092775,-6.565824771,-2.727651449 -961,L74P,-0.015964399,-0.697350252,-1.830984295,-2.271607042,-2.872337698,0.108075012,0.010181735,-0.042110533,0.014847318,-0.553638824,-0.84106168,-1.923141607,-1.738826982,-2.173402605,-2.369811479,-2.71881374,-3.025861656,1.198603967,-0.153828521,-11.90106272,-13.22783706,-12.90607156,-11.97174718,-10.69229533,-10.70736244,-7.806955522,-6.066438327 -962,L74S,-0.003771125,0.008548347,-0.343446151,-1.66620322,-2.599628113,0.092326533,0.02112722,-0.02866947,0.048239239,0.020492923,-0.003396229,-0.277178272,-0.409714029,-1.571837466,-1.760568973,-2.313399654,-2.885856572,1.386835266,0.785447944,-8.341780846,-9.697965408,-8.687616478,-8.763693794,-6.339389084,-8.220239464,-4.851743691,-3.405242374 -963,L74R,-0.026515805,-1.628701234,-2.015487388,-2.382380953,-3.126264978,0.070963716,0.003124173,-0.056155782,-0.170121282,-1.698039301,-1.559363166,-2.092110275,-1.938864501,-2.138251291,-2.626510615,-2.908971707,-3.343558248,0.032323348,-1.100965185,-14.31317348,-14.69366666,-14.40202042,-15.49812894,-12.57450899,-14.39754237,-9.359036783,-9.351992997 -964,L74T,-0.003227403,-0.004661313,0.006254917,0.021064031,-1.513027813,0.089377368,0.006498025,-0.01295283,0.03212495,-0.015056664,0.005734039,0.001354727,0.011155107,0.016138991,0.025989071,-1.513823143,-1.512232482,0.866341883,1.336748996,-7.656981972,-9.718582222,-7.500228951,-7.777633392,-6.69412999,-6.594335304,-5.134492989,-3.168456132 -965,L74W,-0.024041268,-1.503617449,-2.154350156,-2.179020532,-2.903445524,0.071567099,-0.019014534,-0.029068001,-0.057690905,-1.57303208,-1.434202817,-1.773637699,-2.535062612,-2.472991228,-1.885049835,-2.398613605,-3.408277443,-0.680554299,-1.101304165,-13.11447907,-13.5965399,-13.11915235,-14.0319567,-12.02631542,-12.79843099,-9.359036783,-9.351992994 -966,L74V,0.000749941,0.028167892,0.016143763,0.03207235,-0.23273484,-0.006218969,0.010387123,-0.008887241,0.03538782,0.056391283,-0.0000555,0.024151551,0.008135974,0.051911166,0.012233533,-0.186640429,-0.27882925,1.218678127,2.018171883,-3.903289162,-4.606488365,-3.199892586,-3.62885775,-4.816596825,-3.264610283,-3.676973361,-0.336897099 -967,L74Y,0.010092519,-1.554455648,-1.841688992,-2.511994447,-2.935389443,0.061216791,0.056889062,-0.036704025,-0.062648251,-1.821086469,-1.287824827,-1.908987808,-1.774390175,-2.052038836,-2.971950057,-2.8807512,-2.990027686,-0.198091538,-1.0927561,-13.34446195,-13.75930566,-13.0528546,-14.15982388,-11.90029561,-13.85003001,-8.664891979,-6.830301299 -968,C75A,0.046741127,0.053629461,0.006241079,0.005710027,-0.124974444,0.034996118,0.030469565,0.063012689,0.139065715,-0.012971875,0.120230796,-0.042896697,0.055378854,0.036787527,-0.025367473,-0.151809544,-0.098139343,1.382163228,2.234419145,-6.021995253,-6.537822807,-6.683725204,-6.028494698,-5.886421173,-4.973512383,-4.945969968,1.879301736 -969,C75E,-0.042069892,-1.244999978,-1.889743288,-1.905157077,-2.657888088,0.10634143,-0.022570513,-0.061569271,0.137282569,-1.203702849,-1.286297107,-1.711800062,-2.067686514,-1.543892252,-2.266421902,-1.866111547,-3.449664629,4.055323514,2.170935754,-15.37273278,-16.4327984,-14.13451217,-18.20066129,-15.43410025,-12.66159178,-11.23350191,-7.992037776 -970,C75D,0.002994453,-0.452667152,-1.54478751,-2.430277335,-2.621082525,0.103964689,0.010711497,-0.004722591,0.277161655,-0.355898185,-0.549436118,-1.45691201,-1.63266301,-2.162130964,-2.698423706,-2.037192227,-3.204972823,3.825984409,2.155372264,-16.14690484,-16.40199549,-16.58117992,-18.74674195,-16.38843601,-12.61617081,-11.23350191,-7.992037808 -971,C75G,-0.009012161,0.050104729,-0.021442209,-0.008585221,-1.053258683,0.034990562,-0.012263773,-0.005760548,0.129394057,-0.007543584,0.107753042,-0.045917215,0.003032797,0.010505082,-0.027675523,-0.654122542,-1.452394823,1.245417445,1.628211047,-10.04001369,-10.08453535,-9.301021271,-10.29080714,-12.48466212,-8.039042564,-6.099015379,-1.030511794 -972,C75F,-0.016512075,-1.544501752,-2.056827474,-2.148746198,-2.839551388,0.085389886,-0.01170523,-0.021318919,0.00275414,-1.59655816,-1.492445344,-2.091291412,-2.022363535,-1.855631818,-2.441860578,-2.508844332,-3.170258444,0.362554831,-0.956003399,-11.81073969,-12.03612736,-9.764941818,-14.3175526,-13.13954972,-9.795526947,-7.994391099,-2.732038677 -973,C75I,0.081882041,0.063593051,0.015331001,0.031988828,-0.955438898,-0.019458535,0.081873882,0.0818902,0.060953173,0.009901489,0.117284613,-0.010365296,0.041027298,0.042590543,0.021387112,-0.600752753,-1.310125042,0.729132994,1.424116776,-13.22884645,-13.87663499,-11.1798395,-17.00764029,-14.02025236,-10.0598651,-7.755471947,-1.896905193 -974,C75H,0.003912772,-1.379487657,-1.953841552,-2.181696159,-3.295050369,0.130034062,0.020986862,-0.013161319,-0.17733498,-1.497816966,-1.261158348,-1.890520761,-2.017162342,-2.169770982,-2.193621335,-3.169770982,-3.420329755,0.644613288,-0.900141399,-14.25985871,-16.48898833,-14.06549768,-14.3298768,-15.47977629,-10.93515446,-11.23350191,-7.992037793 -975,C75K,0.002156791,-1.715059089,-1.683259221,-1.984412727,-3.147459253,0.134443809,0.016563909,-0.012250327,0.127758999,-1.802923854,-1.627194324,-1.736989799,-1.629528642,-1.636028779,-2.332796675,-2.715210025,-3.579708481,3.993775211,1.655793613,-15.55784837,-16.05559567,-14.87052335,-17.97863459,-15.98027707,-12.90421117,-11.23350191,-7.992037809 -976,C75M,-0.032038209,0.055273305,-0.018830402,-0.314427651,-1.655535905,0.125654216,-0.037707487,-0.026368931,0.003003806,0.011416625,0.099129984,-0.021691368,-0.015969436,-0.084599024,-0.544256277,-1.77635638,-1.534715429,0.86187126,1.315619966,-14.98349964,-15.080151,-11.95112576,-20.36936446,-14.99597459,-12.52088241,-7.630219326,0.413841547 -977,C75L,0.016727476,0.063849148,0.014088865,-1.091201824,-1.869139891,0.060973045,0.02710089,0.006354061,0.107230705,0.01812128,0.109577016,-0.007874999,0.036052729,-0.650956525,-1.531447122,-1.884961893,-1.853317889,1.902342227,1.475603822,-14.08618493,-15.04729922,-10.56240178,-20.47826015,-14.96135421,-9.381609261,-8.059922164,1.05815916 -978,C75N,-0.01472233,-0.032952449,-1.252335921,-1.717129437,-3.233573633,0.1187934,0.007281482,-0.036726141,0.175704015,0.00902519,-0.074930087,-1.208887629,-1.295784213,-1.503377817,-1.930881056,-2.950535848,-3.516611418,2.469540133,1.19706792,-14.0560192,-14.51755788,-14.74995905,-15.02417044,-14.9602105,-11.02819812,-8.837204836,-2.621569283 -979,C75Q,0.000559972,-1.078237665,-1.740257823,-2.392133641,-3.067957219,0.133072744,-0.005513237,0.00663318,0.074472628,-1.02052091,-1.135954419,-1.847376886,-1.633138759,-1.883589059,-2.900678222,-2.55259584,-3.583318597,3.206350552,1.170659143,-14.59543297,-14.65206615,-13.97835094,-17.88962863,-14.89940788,-11.55771124,-8.673551272,-3.019107175 -980,C75P,-0.006089856,-1.308213605,-2.087607773,-2.350018806,-2.963701034,0.127993767,0.003102149,-0.01528186,0.008079928,-1.359678203,-1.256749007,-2.21293937,-1.962276175,-2.292958529,-2.407079083,-2.761961894,-3.165440173,0.03790081,-0.829157616,-15.69223567,-15.90535382,-15.42069778,-17.9688344,-15.91687516,-13.24941718,-11.23350191,-7.992037759 -981,C75S,0.013160894,0.051938005,-0.008555905,-0.023008404,-1.618066015,0.099583343,0.018974801,0.007346986,0.036206558,-0.033574772,0.137450782,-0.028859652,0.011747843,0.041303692,-0.0873205,-1.651389997,-1.584742032,0.447381893,1.304622815,-8.195389909,-8.367662445,-8.270373199,-8.237214943,-9.456881699,-6.644817261,-6.359603078,-1.030224062 -982,C75R,-0.010354531,-1.410148099,-1.852716616,-1.983992597,-2.91011735,0.134217501,-0.012279035,-0.008430027,-0.072560264,-1.540947393,-1.279348804,-1.648763382,-2.056669849,-1.839591701,-2.128393492,-2.942254043,-2.877980657,3.648520262,1.399044997,-15.72674646,-15.61574667,-15.15561286,-18.98158174,-15.87285349,-13.00793752,-11.20940465,-7.934973023 -983,C75T,-0.001445077,0.055769816,-0.009663601,0.01817083,-1.171416675,0.104844254,-0.010699139,0.007808986,0.040319068,0.020604023,0.090935609,-0.010773875,-0.008553326,0.087835062,-0.051493402,-0.849231587,-1.493601763,0.614711037,1.359127406,-10.06911689,-10.21140649,-10.41581057,-12.10150461,-8.560587173,-9.056275604,-7.139915716,-2.103690215 -984,C75W,-0.011349745,-1.422312749,-1.636064596,-1.759551568,-2.412726065,0.116880579,-0.003410364,-0.019289126,-0.072115872,-1.35645951,-1.488165988,-1.490097811,-1.78203138,-1.603016611,-1.916086525,-2.468318037,-2.357134093,4.041460235,2.057022132,-15.65972502,-16.03973476,-13.98582176,-19.11966448,-16.32206633,-12.83133775,-11.23350191,-7.992037787 -985,C75V,0.027750647,0.044840223,-0.002847877,0.030028576,-0.262256631,0.046313754,0.009275872,0.046225422,0.123543642,-0.019944771,0.109625217,-0.047027432,0.041331679,0.046571937,0.013485215,-0.229096412,-0.295416849,1.133656501,1.842978875,-9.734516252,-10.0006363,-8.49402919,-13.68894885,-10.2422309,-6.246736015,-5.209353603,0.309955902 -986,C75Y,-0.01161151,-1.423035694,-2.098222631,-2.128243143,-2.982064465,0.108933845,0.005924393,-0.029147413,-0.095825071,-1.493940291,-1.352131096,-2.206157487,-1.990287775,-1.769404365,-2.48708192,-2.230135203,-3.733993726,4.220120555,1.789117237,-13.13671996,-14.49208458,-11.170602,-14.55326479,-14.46130765,-11.00634081,-10.41093462,-5.502652412 -987,G76A,-0.000738163,-0.001160087,-0.018194826,0.001006891,-0.006424417,0.018457521,-0.029481988,0.028005663,-0.065810954,-0.021910584,0.01959041,-0.035236644,-0.001153007,-0.056300585,0.058314367,-0.008636806,-0.004212027,1.304413005,2.549351083,-1.200531851,-0.024408241,-1.85162513,-1.303297012,-1.359960396,-1.463368477,-2.099228852,1.087358853 -988,G76C,-0.198757879,0.002186972,-0.034950044,-0.007290336,-1.115576811,0.071541575,0.034835408,-0.432351165,-0.08730112,0.007747121,-0.003373178,-0.012986836,-0.056913252,0.010538479,-0.025119151,-1.329702596,-0.901451025,0.701315566,1.33133805,-9.87600731,-8.467379417,-10.86103766,-10.10920348,-8.510099426,-11.43231657,-7.132300718,-2.871840378 -989,G76E,0.008772829,-0.916709565,-2.03972138,-2.264288271,-3.053755801,-0.058138796,-0.039724711,0.057270368,0.228247592,-0.933237376,-0.900181754,-2.251976209,-1.82746655,-2.788361424,-1.740215118,-2.974592315,-3.132919287,0.059159831,-0.635101906,-11.07087691,-9.048050613,-11.99926998,-11.88263485,-9.3270019,-13.09742722,-9.05037166,-5.046374088 -990,G76D,-0.028952877,-1.01935933,-1.624557009,-1.872623223,-2.342334093,-0.001329793,-0.010277066,-0.047628687,-0.133725183,-0.887388145,-1.151330515,-1.617526534,-1.631587483,-1.781525845,-1.963720601,-2.532028165,-2.15264002,4.170725486,2.274669865,-12.00406741,-9.90292691,-13.38555005,-12.3356143,-10.23137534,-14.16487047,-8.951541506,-4.53808911 -991,G76F,-0.234070932,-0.006641147,-0.047276712,-0.503509116,-1.789810329,0.013959386,-0.052669606,-0.415472257,0.007964036,-0.033884149,0.020601856,-0.03339487,-0.061158554,-0.343253668,-0.663764563,-1.723350906,-1.856269751,1.541912824,1.408774277,-13.38580712,-9.913575203,-18.05843806,-13.84785667,-9.932236183,-15.1769295,-6.994403718,-3.014590232 -992,G76I,-0.101196517,0.048162336,-0.00374222,-0.181536453,-1.814070833,-0.013149393,0.00211033,-0.204503364,-0.018841866,0.030061694,0.066262977,-0.006485806,-0.000998633,-0.073479802,-0.289593104,-1.779046382,-1.849095284,0.919501268,1.31834731,-12.07713985,-9.643192925,-17.36902167,-11.99789848,-8.201432404,-13.17415376,-5.730877222,-0.150529824 -993,G76H,-0.134159257,-0.018706078,-1.313328212,-1.907667324,-3.483680472,0.027627272,-0.032598102,-0.235720411,-0.115415485,-0.006670617,-0.030741539,-1.210740224,-1.4159162,-1.988569745,-1.826764903,-2.987713992,-3.979646952,2.380131454,0.957865452,-12.87813787,-10.75860352,-14.54335578,-12.44305228,-10.47151653,-16.17416124,-9.045547994,-5.442607147 -994,G76K,-0.113014976,-1.515354415,-2.578043726,-2.536526207,-3.35351752,0.015415391,0.009617812,-0.235647763,-0.017333373,-1.615286692,-1.415422138,-2.786422804,-2.369664648,-2.845686764,-2.227365649,-3.031917655,-3.675117384,-0.61353004,-1.061962419,-13.21164809,-11.23691766,-14.24152084,-13.74595574,-11.0989102,-15.73493602,-10.62194635,-8.459220224 -995,G76M,-0.111854985,-0.017873828,-0.072054776,-0.03370548,-1.799435365,0.005460086,-0.017291178,-0.206418792,0.064522814,-0.017806984,-0.017940672,-0.058796838,-0.085312714,-0.081806616,0.014395656,-1.609013342,-1.989857387,0.941426503,1.332580026,-10.1585078,-8.655023178,-12.81938037,-12.76938689,-5.755202675,-10.79354589,-6.925766167,-0.942366561 -996,G76L,-0.18781035,-0.010261449,-0.052465517,-0.267438362,-1.685606461,0.023415574,-0.045727101,-0.329893598,0.048865083,-0.016494476,-0.004028422,-0.06234852,-0.042582514,-0.20654392,-0.328332803,-1.693156121,-1.678056801,1.249992733,1.361508748,-12.21902982,-8.925948875,-15.86740022,-14.52306777,-7.54232045,-14.2364118,-7.04125587,0.141392842 -997,G76N,-0.134887876,-0.61516894,-1.880766075,-2.173751946,-3.363726542,0.096539001,-0.034271306,-0.235504445,0.034158271,-0.469958948,-0.760378931,-2.0296276,-1.731904549,-1.912800302,-2.43470359,-2.877182442,-3.850270642,1.201050117,-0.14749067,-11.42889529,-10.39482754,-12.38905901,-11.5962772,-9.627952705,-13.13635999,-8.978125014,-4.971853758 -998,G76Q,-0.161950913,-0.351404195,-1.60826415,-2.044045221,-3.35474197,0.025706504,-0.066368631,-0.257533195,0.038316126,-0.240816258,-0.461992131,-1.469944317,-1.746583983,-1.927148286,-2.160942155,-3.016469163,-3.693014777,2.695028868,1.096259539,-12.56167703,-10.26981557,-13.87873647,-13.74278053,-10.28445824,-14.63259434,-9.757290569,-6.103613039 -999,G76P,-0.125741076,-1.242940786,-2.095809735,-2.371980644,-3.236796638,0.0435326,-0.024767721,-0.226714431,-0.1206714,-1.205087431,-1.280794141,-2.169230598,-2.022388872,-2.351211835,-2.392749453,-2.905419511,-3.568173764,0.807129804,-0.696821541,-12.63899756,-10.4596858,-14.55797478,-13.2111504,-11.13223648,-13.83394034,-10.62194635,-8.459220224 -1000,G76S,-0.148380241,0.002876817,-0.035051833,0.007652341,-0.032136065,0.021518844,0.001180666,-0.297941148,-0.018531835,-0.000828168,0.006581801,-0.027534699,-0.042568966,-0.039597059,0.05490174,-0.048974101,-0.015298029,1.178277762,2.260932028,-5.318448616,-4.54477906,-5.963392128,-5.16715947,-4.59249707,-6.324415352,-4.508262633,-1.755396225 -1001,G76R,-0.134686661,-1.573394212,-2.063019504,-2.276991746,-3.250447668,0.047713788,-0.032776549,-0.236596772,-0.14671691,-1.750179799,-1.396608624,-1.979307857,-2.146731151,-2.369565037,-2.184418455,-3.400893967,-3.100001369,-0.062491885,-1.110049036,-13.42546097,-10.79571595,-15.16512668,-14.63967319,-10.77531603,-15.75147298,-10.62194635,-8.459220224 -1002,G76T,-0.117080549,-0.008849978,-0.019513138,0.025075984,-1.521995719,0.040666998,-0.023051415,-0.211109683,-0.045944066,0.034077496,-0.051777452,-0.010705431,-0.028320845,0.004474556,0.045677412,-1.344059309,-1.699932128,0.64031566,1.325629399,-8.247744933,-6.718817871,-10.2868671,-8.805021767,-6.865672493,-8.562345436,-6.459458243,-2.48513455 -1003,G76W,-0.207987571,0.017081838,-0.035151501,-0.274966587,-1.716033837,0.048832404,-0.01063423,-0.405340912,0.013977023,0.040872495,-0.00670882,-0.000870539,-0.069432462,-0.154467089,-0.395466084,-1.739280912,-1.692786761,1.097686333,1.336201203,-13.2293235,-10.44728798,-16.7906634,-14.16896783,-10.30122847,-14.43846983,-7.738709739,-3.211624431 -1004,G76V,-0.00396612,0.017771212,-0.024386902,-0.417341658,-1.887239644,0.022038914,-0.017859548,0.009927309,-0.080552931,0.01111713,0.024425293,-0.022574493,-0.026199311,-0.281410809,-0.553272507,-1.717893403,-2.056585884,1.39720832,1.383527699,-10.13630155,-7.92838829,-15.16519548,-9.837261543,-6.605335571,-11.14532687,-7.315529146,-0.05330168 -1005,G76Y,-0.275535708,-0.007914146,-0.05184862,-0.603999159,-1.7525129,-0.023435333,-0.124975431,-0.426095984,-0.041165982,0.011095553,-0.026923845,-0.012229861,-0.091467378,-0.429509287,-0.77848903,-1.735854781,-1.769171019,1.631429035,1.433211156,-13.36634782,-10.45146325,-17.81374196,-12.80981652,-9.81697261,-15.93974477,-7.690368364,-2.654338128 -1006,A77C,0.037604814,0.015472764,0.004788188,-0.00573169,0.031666339,0.021386353,-0.015816749,0.091026377,-0.227021352,0.003102691,0.027842837,-0.059651797,0.069228172,-0.046057236,0.034593857,-0.00269428,0.066026958,1.163389478,2.450149109,-6.687918579,-6.873618767,-8.53809726,-6.583049622,-6.898452515,-4.546374733,-4.518973297,-3.728902113 -1007,A77E,-0.020805263,0.022256053,0.037595676,-0.011047973,-1.10575645,0.033872913,-0.030346953,-0.011263573,-0.20515938,0.109127125,-0.06461502,-0.00209269,0.077284041,-0.036537168,0.014441223,-0.882304339,-1.329208561,0.802578173,1.386337547,-6.872925688,-5.528636932,-6.50172403,-9.387667191,-6.239468391,-6.707131897,-4.947344413,-1.374890572 -1008,A77D,0.036566998,-0.025913877,0.044084167,0.016677015,-1.23474708,0.031479705,0.02119271,0.051941285,-0.237047685,-0.009449233,-0.04237852,-0.028319379,0.116487712,-0.041325651,0.07467968,-0.803485109,-1.666009051,1.208150076,1.523293688,-8.96999187,-7.984231644,-9.527714096,-10.84476405,-7.640491097,-8.852758469,-6.157526356,-5.308886177 -1009,A77G,0.035843381,-0.015141845,0.002624282,-0.004488878,-1.152291686,0.059663814,-0.014576562,0.086263323,-0.259007922,-0.006651539,-0.02363215,-0.062502086,0.06775065,-0.061004575,0.052026819,-0.889494518,-1.415088854,0.958543602,1.418953336,-5.123640797,-4.924544571,-5.048627831,-5.914195175,-5.45094133,-4.279895081,-3.806464828,-2.882959615 -1010,A77F,0.057450019,-0.048037249,-0.032784544,-0.039051586,-0.047762399,-0.036731018,-0.008953301,0.123853338,-0.407485327,-0.071891513,-0.024182985,-0.065785487,0.000216399,-0.140964595,0.062861424,-0.105126731,0.009601933,1.402876335,2.227808267,-9.728875563,-9.167750801,-12.35118193,-10.84643547,-9.122790863,-7.15621875,-4.125372127,-3.792054397 -1011,A77I,0.006484655,-0.014691527,-0.008791757,0.021222738,-0.447714455,0.00247353,-0.030787515,0.043756824,-0.287457188,0.058541581,-0.087924635,-0.015839211,-0.001744302,0.005720867,0.036724608,-0.289412826,-0.606016083,0.938011716,1.666169523,-8.236519081,-6.450390083,-9.371478874,-10.40665878,-7.827270943,-7.126796722,-5.125156489,-4.15581182 -1012,A77H,0.071173928,-0.007256348,-0.000492809,0.014397303,-0.045084475,-0.014020655,0.056911066,0.08543679,-0.209614293,-0.035441554,0.020928859,-0.106102848,0.10511723,-0.08401565,0.112810256,-0.056471405,-0.033697545,1.431794363,2.471484108,-8.047659973,-6.917164146,-11.26828677,-8.624624062,-5.843152016,-7.585072868,-4.435187592,-4.108565032 -1013,A77K,0.049965434,-0.050122967,-0.003180972,-0.013919142,-0.101616997,0.008047406,0.030146283,0.069784584,-0.27733533,-0.088908516,-0.011337417,-0.077647132,0.071285189,-0.129339521,0.101501238,-0.115850357,-0.087383636,1.36111989,2.194949085,-6.539634908,-4.241741005,-7.739748337,-8.565202744,-5.930411247,-6.221071205,-3.98182045,-3.451015588 -1014,A77M,0.013687251,0.00436159,0.031667438,0.024997295,0.00367316,-0.03223846,-0.026222899,0.0535974,-0.185354659,0.11562127,-0.106898091,0.015345945,0.047988931,0.016981068,0.033013522,0.055367673,-0.048021353,1.242435059,2.981332762,-7.167273814,-4.589065338,-8.378811325,-9.604229355,-6.893565315,-6.370697739,-5.0985153,-3.802084299 -1015,A77L,0.031469627,-0.017614538,0.016396292,-0.003183666,-0.05205512,-0.051001332,0.009771245,0.053168008,-0.183521963,-0.016131936,-0.01909714,-0.055406156,0.088198739,-0.048412352,0.042045021,-0.078326688,-0.025783552,1.320269367,2.290104142,-6.930419084,-4.6673909,-8.719584595,-8.201834305,-6.861184631,-6.20210099,-3.234713777,-2.70753155 -1016,A77N,0.030823456,-0.04101871,0.015666112,-0.014621359,-0.102364519,-0.022762532,0.027109297,0.034537614,-0.21387982,-0.056366389,-0.025671031,-0.045303428,0.076635652,-0.017127761,-0.012114956,-0.124007669,-0.080721368,1.203668451,2.104324851,-7.608313084,-7.327210548,-9.30059819,-8.129589935,-5.825809151,-7.458357597,-4.79708571,-4.378504849 -1017,A77Q,0.006138258,-0.058917172,-0.029064326,-0.052379304,-0.053635759,-0.031816009,0.004151226,0.008125289,-0.241261791,-0.044126279,-0.073708065,-0.1043544,0.046225748,-0.085366794,-0.019391814,-0.102259575,-0.005011942,1.304313342,2.205744571,-6.975806459,-4.619848129,-7.561933342,-8.821864418,-6.462393745,-7.412992661,-4.803229085,-3.246582107 -1018,A77P,0.004131451,-0.284897205,-1.557641204,-2.169907644,-2.5264617,0.00471968,0.010424912,-0.00216201,-0.108881659,-0.164171972,-0.405622438,-1.593847281,-1.521435127,-1.982817248,-2.35699804,-2.181949811,-2.870973588,3.766617301,2.09751268,-10.65186323,-9.572050697,-11.42293325,-11.79851699,-10.08500626,-10.38080894,-8.705427632,-9.614531994 -1019,A77S,0.035106804,0.013368553,0.03985466,0.016302597,-0.106346494,0.011849931,-0.012605698,0.082819306,-0.241940513,0.031791303,-0.005054197,-0.01579498,0.095504299,0.000641256,0.031963938,-0.072667428,-0.14002556,1.181659527,2.237635008,-5.185596034,-5.086449554,-5.699865585,-5.931232628,-4.650163231,-4.560269173,-3.635938546,-3.443494686 -1020,A77R,0.025660961,-0.021739187,-0.007012498,-0.018575674,-0.388606684,0.019988571,0.010319694,0.041002228,-0.210810145,-0.014066538,-0.029411836,-0.078259663,0.064234668,-0.085770658,0.048619311,-0.307798274,-0.469415093,1.753896115,2.219907593,-8.118550456,-5.531459717,-10.8182807,-10.05234763,-6.265542084,-7.925122154,-4.443004864,-3.401166558 -1021,A77T,0.009135381,-0.011429865,0.00021455,-0.038796865,-0.233979562,0.068669667,0.003588596,0.014682165,-0.204119983,0.038977861,-0.06183759,-0.037889701,0.0383188,-0.07170419,-0.005889539,-0.177013485,-0.290945638,1.419586028,2.150478767,-4.972706778,-3.480718849,-4.79836515,-6.730765915,-4.34101107,-5.512672905,-4.687920605,-1.884930054 -1022,A77W,-0.010037885,-0.022470443,0.006612425,-0.025782612,-1.647934247,0.050072348,-0.000129716,-0.019946054,-0.241284109,0.028475421,-0.073416306,-0.056452132,0.069676982,-0.070629683,0.019064459,-1.573300206,-1.722568287,0.63772385,1.31531363,-11.41652313,-10.15662836,-13.12126321,-12.40772763,-10.63035065,-10.76664582,-5.927785992,-5.807111518 -1023,A77V,0.006094167,-0.003418942,0.011197465,-0.005472483,-0.046064699,-0.034080658,-0.029416144,0.041604478,-0.242265053,0.011493496,-0.018331379,-0.031502744,0.053897673,-0.038540103,0.027595138,-0.058241832,-0.033887565,1.358902165,2.418300926,-5.388092123,-4.095331833,-5.560470581,-7.212319649,-5.335764526,-4.736574028,-3.448575308,-2.704954122 -1024,A77Y,-0.001738225,0.008319888,-0.003515975,0.00039913,-0.015251162,-0.045957843,-0.058565023,0.055088573,-0.258101795,0.057562292,-0.040922517,-0.021157086,0.014125136,0.012656703,-0.011858443,0.041536724,-0.072039047,1.190884922,2.819835845,-10.13204072,-8.911687645,-13.10412857,-11.08639387,-8.902134605,-8.655858894,-5.125928953,-3.537439358 -1025,V78A,-0.027555502,0.028317385,-0.03081787,-0.027847158,-1.656196595,0.054383624,0.004113835,-0.059224838,-0.004426986,0.034597035,0.022037735,-0.020579704,-0.041056035,-0.008189373,-0.047504942,-1.430548026,-1.881845163,0.857223423,1.337815564,-4.062076318,-4.202271973,-3.100818359,-5.820414177,-3.462512886,-3.724364197,-3.711987308,-1.333522514 -1026,V78C,0.026739392,0.036746746,0.019432161,-0.185336551,-1.68324771,0.096692724,0.033276344,0.020202439,-0.009745623,0.08511134,-0.011617849,0.007092815,0.031771507,-0.088117028,-0.282556074,-1.536393821,-1.830101598,0.793518574,1.324609094,-8.693039894,-7.206258438,-6.377994087,-12.60800379,-9.155328796,-8.117614357,-5.841966481,-4.404980384 -1027,V78E,0.057113482,0.036711092,-0.101339832,-1.556595863,-2.698340925,0.025070162,0.064694858,0.049532106,0.009347684,0.034849078,0.038573105,-0.056752441,-0.145927223,-1.496376054,-1.616815671,-2.603828308,-2.792853541,0.778186905,0.710328044,-10.5324279,-10.24104378,-8.616250893,-13.796377,-9.903016609,-10.10545122,-8.519744082,-7.302159776 -1028,V78D,0.020108278,-0.539073526,-1.898579971,-2.677275235,-2.787729305,0.011166081,0.043481415,-0.00326486,0.08870515,-0.27724747,-0.800899582,-1.474267269,-2.322892672,-2.42700979,-2.927540679,-2.493069359,-3.08238925,1.242355429,0.108476669,-11.68439271,-11.5038268,-9.476012062,-15.49437652,-11.1300443,-10.81770385,-9.404967002,-9.769835496 -1029,V78G,-0.027763323,-0.046947496,-1.31711,-2.105566334,-3.18578003,0.083098031,-0.004739427,-0.050787218,0.02351664,0.010964569,-0.10485956,-1.223340159,-1.410879841,-2.118090733,-2.093041934,-3.138392812,-3.233167248,0.891093156,0.111617042,-9.755791618,-9.511101875,-7.396039032,-13.43148764,-9.277208099,-9.163121445,-6.645698291,-3.918137876 -1030,V78F,-0.025469275,-0.022839963,-0.050249756,-0.880751637,-2.180567854,0.019111484,-0.029308288,-0.021630261,0.072448266,0.013446943,-0.059126869,-0.065957977,-0.034541535,-0.476853914,-1.28464936,-1.929858107,-2.4312776,1.503619779,1.345472145,-8.935931407,-7.664467865,-6.085883789,-13.64936545,-10.99159146,-6.288348473,-5.128154225,-1.780454082 -1031,V78I,-0.062067489,0.016499933,0.051312049,-0.003313895,0.000169684,-0.012927375,-0.100050322,-0.024084655,-0.103811618,0.097941599,-0.064941734,0.109716569,-0.007092472,0.069588418,-0.076216208,0.10772554,-0.107386172,1.080855097,3.098463001,-1.321723781,-1.0785215,-0.861712845,-1.934250458,-1.704240578,-1.029893524,-2.40347452,-1.458571152 -1032,V78H,-0.016270898,0.010942452,0.028227537,-1.395238734,-2.543009613,0.028662818,0.00107947,-0.033621265,0.01578637,0.126303282,-0.104418378,0.09684216,-0.040387086,-1.133449261,-1.657028207,-2.177232435,-2.908786791,0.916804627,0.76543097,-13.10812769,-11.4709725,-10.43869939,-18.63355664,-13.11593847,-11.88147144,-9.404967002,-9.769835496 -1033,V78K,0.001839118,-0.040107999,-1.266341998,-1.86552629,-2.59120482,0.035098778,0.042531337,-0.038853101,0.066450097,0.034246193,-0.11446219,-1.242360167,-1.290323828,-1.920401631,-1.810650949,-2.287491195,-2.894918445,3.081158498,1.624375066,-11.34127313,-10.80767766,-8.72908091,-14.58131466,-10.94871952,-11.63957289,-9.404967002,-9.769835496 -1034,V78M,-0.061921223,0.0024918,-0.035672751,-0.051007133,-0.582851742,-0.044427402,-0.074949591,-0.048892855,0.02369312,0.063219975,-0.058236376,-0.00238476,-0.068960742,-0.029490996,-0.072523269,-0.388598315,-0.777105168,1.325946355,1.813477872,-5.577692776,-3.782774368,-3.86007341,-8.493511444,-5.767599442,-5.984505219,-4.561860221,-2.828694156 -1035,V78L,0.010158283,0.039151264,-0.014894887,-0.010168567,-0.34449891,-0.017061268,0.015847088,0.004469477,0.03760816,0.056109612,0.022192916,-0.005619712,-0.024170061,-0.00663738,-0.013699753,-0.244243085,-0.444754735,1.120110615,1.819710138,-3.771456212,-2.371703178,-1.886697784,-6.049359871,-4.538904533,-4.010615692,-2.25114419,-0.698352594 -1036,V78N,0.109613889,0.106997241,-0.776347478,-2.041028381,-2.753542442,0.11098701,0.134712585,0.084515192,0.037409083,0.081191342,0.13280314,-0.719264977,-0.833429979,-1.519040039,-2.563016722,-2.488189594,-3.018895289,2.245832708,1.178570647,-10.83381969,-9.959333588,-9.126215126,-14.98013526,-10.47648077,-9.626933723,-8.570608566,-7.304091845 -1037,V78Q,-0.004544015,0.064502859,-0.090802632,-1.611977588,-2.523461653,0.087838506,0.034859493,-0.043947523,-0.051435077,0.099517596,0.029488121,-0.088363842,-0.093241422,-1.478790879,-1.745164296,-2.146910439,-2.900012867,2.444705609,1.527175785,-11.20310578,-10.55054248,-9.018334068,-14.27371986,-10.66071827,-11.51221422,-9.404967002,-9.769835496 -1038,V78P,0.007812376,-1.383929418,-2.338744619,-2.553140845,-3.162109295,0.041470082,0.013359995,0.002264756,-0.051943431,-1.420364231,-1.347494605,-2.255159574,-2.422329664,-2.202149766,-2.904131923,-2.944902945,-3.379315645,0.164255557,-0.911421551,-11.28568029,-10.96703996,-9.456898598,-14.24493577,-11.2232063,-10.53632084,-9.18009789,-8.885780033 -1039,V78S,0.000057,-0.01492458,-0.029728687,-1.581822507,-2.741822616,0.055886709,0.032656862,-0.032542877,0.060577734,0.000567411,-0.03041657,-0.049098695,-0.010358678,-1.451837586,-1.711807427,-2.545925878,-2.937719354,0.802916582,0.716132736,-8.805281395,-8.415005096,-7.566246788,-12.84734567,-8.017875366,-7.179934059,-7.159195795,-5.310112065 -1040,V78R,-0.016696638,-0.881776466,-2.15087015,-2.720000761,-3.102488852,0.075508736,0.013823101,-0.047216376,-0.026863254,-0.781738697,-0.981814234,-2.078143128,-2.223597172,-2.18578761,-3.254213911,-2.494885227,-3.710092477,1.163432303,-0.380500606,-11.77599404,-11.200096,-9.295713226,-14.83683981,-11.28011063,-12.26721054,-9.404967002,-9.769835496 -1041,V78T,-0.047361462,-0.013638888,-0.036233974,-0.017847592,-1.133446022,0.085036623,-0.019340307,-0.075382617,-0.025164889,0.064966671,-0.092244446,-0.010690881,-0.061777067,0.016883013,-0.052578196,-0.827327806,-1.439564238,0.692638122,1.373077779,-4.782004752,-4.64653241,-3.81305806,-6.092572174,-4.074017715,-5.283843399,-4.947254074,-2.457017067 -1042,V78W,-0.015194464,-0.006698435,-0.188115187,-1.626287272,-3.018125613,0.016416326,-0.007709725,-0.022679202,-0.007536352,0.000493439,-0.013890309,-0.185521987,-0.190708386,-1.543628536,-1.708946007,-3.072086102,-2.964165123,1.068385064,0.733182279,-10.98333531,-9.522569191,-8.576773697,-14.5115048,-12.81020496,-9.495623878,-7.553206131,-5.550567107 -1043,V78Y,-0.011703516,-0.001238355,-0.140580622,-1.732783391,-3.024101379,-0.005414191,0.032659973,-0.056067004,0.055128393,-0.008961695,0.006484985,-0.17904832,-0.102112923,-1.48081484,-1.984751942,-2.908602245,-3.139600513,1.183113953,0.760283116,-10.58229114,-9.315712074,-7.937860329,-15.48936933,-12.09290049,-8.075613487,-6.379704826,-3.329321517 -1044,L79A,-0.027199496,0.020965509,-0.000329437,-1.400448323,-2.179578454,0.052610228,-0.025240415,-0.029158577,-0.140901066,0.026562281,0.015368737,0.0000384,-0.000697274,-1.18187343,-1.619023216,-2.117712719,-2.241444188,0.779356868,0.735947185,-11.44791021,-11.79618906,-8.965540764,-10.03492208,-11.18583176,-15.25706737,-7.451637468,-2.830219189 -1045,L79C,-0.052613768,0.020461453,0.02222396,-1.380063308,-2.26771596,0.091646041,-0.020622069,-0.084605466,0.118005724,0.017321625,0.02360128,0.038542863,0.005905057,-1.068190641,-1.691935975,-2.109224609,-2.42620731,2.142608125,1.463108565,-11.53625072,-9.723113419,-10.25314166,-11.93094589,-12.21417496,-13.55987766,-7.516621911,-3.564617519 -1046,L79E,-0.024628399,0.002605446,-0.999195278,-1.888136488,-3.129028942,0.021471003,-0.021610084,-0.027646713,0.144334663,0.03382983,-0.028618938,-0.933556718,-1.064833838,-1.766970123,-2.009302853,-2.827748149,-3.430309735,2.250832959,1.037657499,-13.09266496,-11.97408675,-11.3318261,-12.04619616,-13.45608823,-16.65512756,-8.190376404,-5.159379883 -1047,L79D,-0.01514938,-1.096653208,-1.993373786,-3.157187585,-3.060879132,0.026019673,-0.015715118,-0.014583641,0.172363387,-1.074835993,-1.118470422,-2.023147651,-1.96359992,-2.90002675,-3.414348419,-2.529441012,-3.592317252,0.054865335,-0.680379566,-16.64588079,-16.71652667,-15.2881912,-15.60343378,-16.19079913,-19.43045316,-10.88598105,-10.08874765 -1048,L79G,-0.028099123,-0.019732319,-1.070240267,-2.059000909,-2.957194765,0.054761721,-0.012649117,-0.043549128,0.03239566,-0.000253641,-0.039210997,-1.023416898,-1.117063636,-1.785576425,-2.332425393,-2.591081946,-3.323307583,2.462287334,1.159028495,-14.18183921,-13.76888288,-11.84847445,-13.88775539,-14.25061777,-17.15346558,-8.597913308,-5.714715274 -1049,L79F,-0.01025245,0.012232916,-0.029724263,-1.093196663,-1.868020467,0.033997307,0.008388181,-0.028893081,0.037664813,0.010527574,0.013938257,-0.044932282,-0.014516244,-0.831383496,-1.355009829,-1.716070263,-2.019970671,2.504333843,1.900523043,-8.465023422,-10.94694992,-6.956252144,-7.58403598,-8.726030571,-8.111848495,-6.441491471,-1.536071291 -1050,L79I,-0.07409731,0.005641341,-0.032207669,-0.280652553,-1.992318096,0.044192605,-0.077112564,-0.071082056,-0.149855908,0.038759872,-0.02747719,0.011413885,-0.075829222,-0.134214241,-0.427090865,-1.826836723,-2.157799469,1.039629019,1.322823716,-8.73838091,-9.859851044,-7.685239365,-8.519657509,-8.507558701,-9.119597931,-7.26152844,-4.890526914 -1051,L79H,0.000578543,-0.048363297,-1.366124024,-2.62410068,-2.337686607,0.034573267,0.011400516,-0.010243431,0.2692734,0.002596363,-0.099322957,-1.160412227,-1.571835821,-2.011737221,-3.236464139,-2.516212746,-2.159160468,2.29428051,0.925031866,-14.11064839,-13.81050754,-11.77828395,-13.10009328,-13.4634135,-18.40094366,-8.004145638,-4.189848299 -1052,L79K,-0.027209036,-0.899497383,-2.748881899,-2.66842034,-2.660157517,0.070415053,-0.065772639,0.011354567,0.427635892,-0.867642581,-0.931352184,-2.543412781,-2.954351017,-2.274163844,-3.062676835,-2.380699361,-2.939615673,-0.356233052,-0.635022142,-15.0862654,-15.2202095,-13.30032058,-13.88620414,-13.989713,-19.03487977,-9.985118026,-7.714184998 -1053,L79M,-0.041127222,-0.0000792,0.011891843,0.017498071,-0.136681748,0.062130882,-0.028895415,-0.053359028,-0.212987495,0.009610322,-0.009768671,0.048429591,-0.024645906,0.03058431,0.004411832,-0.064670196,-0.2086933,1.279190954,2.398746356,-6.232096787,-7.994527107,-5.208280418,-5.136859695,-6.139987564,-6.680829147,-5.200660259,-2.537645423 -1054,L79N,-0.043601674,0.052140272,-0.723643987,-2.032740067,-2.652113497,0.15569389,-0.009523327,-0.077680021,0.239310176,0.022842391,0.081438153,-0.698685299,-0.748602674,-2.248980298,-1.816499835,-2.355515815,-2.948711178,1.60942797,0.614498822,-14.60604326,-15.12296925,-12.10307977,-14.43522932,-14.18582407,-17.18311392,-8.929622169,-6.37161525 -1055,L79Q,0.029095556,-0.006962172,-0.057202848,-1.464256965,-2.306304801,0.049686828,0.032523022,0.02566809,0.20039211,-0.034112999,0.020188656,-0.081494269,-0.032911427,-1.544639092,-1.383874838,-2.404502275,-2.208107326,0.850925784,0.712602269,-12.89702171,-12.73980621,-10.67189474,-11.81076484,-11.49293997,-17.76970277,-8.532294561,-6.160538968 -1056,L79P,-0.041661111,-1.422050147,-2.334715798,-2.613714355,-3.139544463,0.065740545,-0.036098863,-0.047223359,0.015535506,-1.473903113,-1.370197181,-2.195430804,-2.474000792,-2.201404599,-3.02602411,-2.643732217,-3.635356708,-0.187841378,-0.923340347,-15.2123558,-15.86277149,-13.32132626,-14.41690884,-14.90249727,-17.55827515,-10.88152322,-10.06790871 -1057,L79S,-0.034683821,-0.026581004,-0.329449314,-1.670463279,-2.546889119,0.083495357,-0.023753396,-0.045614245,0.086177239,-0.017654719,-0.035507289,-0.233020446,-0.425878182,-1.401052184,-1.939874374,-2.23998146,-2.853796778,2.408364335,1.470618163,-13.93018694,-14.21009344,-11.30063876,-14.0202532,-14.11391738,-16.00603193,-8.822694093,-6.255023102 -1058,L79R,-0.025002387,-0.630070772,-2.07486141,-2.640855904,-2.817926043,0.085764392,-0.012735762,-0.037269012,0.186603826,-0.559063235,-0.701078309,-2.210009851,-1.939712969,-2.287548401,-2.994163406,-3.047296431,-2.588555654,0.337410538,-0.510504784,-14.91602951,-15.4134371,-12.60615955,-13.20636533,-13.14023171,-20.21395383,-9.344230412,-6.655404396 -1059,L79T,0.015913008,0.000222763,-0.463125385,-1.760315346,-2.2124619,0.066973833,0.017578826,0.01424719,0.364248913,-0.03315881,0.033604336,-0.36843225,-0.55781852,-1.441605994,-2.079024697,-2.042991532,-2.381932267,3.050034408,2.029006614,-12.1605653,-12.09567677,-10.89824052,-11.17848842,-12.35365549,-14.27676527,-7.929140714,-5.677033493 -1060,L79W,-0.060461618,-0.555970982,-1.952050308,-2.538815624,-2.385535496,0.03155105,-0.044539752,-0.076383484,0.140178703,-0.43340531,-0.678536653,-1.925785012,-1.978315603,-2.434687326,-2.642943921,-2.365131584,-2.405939407,1.266555669,-0.068952325,-12.43776017,-13.86545841,-10.26577203,-11.42909258,-12.05515448,-14.57332337,-8.433482967,-6.189235158 -1061,L79V,-0.045812026,0.014359393,-0.002079734,-0.039006771,-1.786521316,0.067834647,-0.038276681,-0.05334737,0.001473321,0.019365586,0.009353199,0.011073528,-0.015232996,0.010527672,-0.088541214,-1.64900771,-1.924034921,0.576076295,1.307886431,-8.534597427,-8.64973278,-7.34083844,-8.09098098,-8.092796036,-10.4986389,-6.740706465,-4.545376001 -1062,L79Y,-0.036318317,0.00616585,-0.431122374,-1.720367866,-3.023729688,0.048682853,-0.017739712,-0.054896922,0.31503089,0.022461264,-0.010129565,-0.280711953,-0.581532794,-1.458621048,-1.982114684,-2.7112846,-3.336174776,1.370118714,0.802306306,-12.49143999,-14.73701756,-10.55982866,-11.02231803,-11.60971087,-14.52832485,-8.090072069,-2.041093615 -1063,S80A,0.003780435,-0.000112187,-0.023835066,-0.039978282,0.008730478,-0.045163348,-0.005619985,0.013180854,0.009412882,0.027437279,-0.027661653,-0.007235321,-0.040434811,-0.016718541,-0.063238022,0.013631965,0.00382899,1.129499537,2.631264114,0.658957611,0.035413864,1.065093132,1.090233009,0.001878448,1.102169601,-1.373942544,1.049533607 -1064,S80C,-0.019945796,-0.005649763,0.022313335,-0.003480105,-1.017420265,0.025241578,-0.043087944,0.003196352,-0.000424303,0.006851626,-0.018151152,0.037051623,0.007575046,0.018116052,-0.025076262,-0.706796778,-1.328043751,0.677427801,1.388823255,-6.109152402,-5.983003471,-7.553816521,-5.99990728,-5.361860291,-5.647174446,-6.990002912,-2.747641107 -1065,S80E,0.065645263,0.133452431,0.070824647,0.0431435,0.100922601,0.041882749,0.07877806,0.052512465,0.010391963,0.120139854,0.146765007,0.044151964,0.09749733,-0.065543575,0.151830574,0.025852224,0.175992978,1.205110646,2.659023445,-3.624621146,-2.346104378,-4.472059776,-4.61055278,-2.958171516,-3.736217278,-4.341704233,0.485227073 -1066,S80D,0.052241377,0.036279143,0.049174175,-0.017654791,-0.217070919,-0.023723154,0.056517916,0.047964837,-0.078792483,0.071720084,0.000838202,0.085544649,0.012803701,0.088448043,-0.123757625,-0.11083853,-0.323303307,1.349599622,2.338894857,-2.988735117,-1.723924599,-3.115274437,-3.960526711,-2.944482101,-3.199467735,-4.51670741,0.864028315 -1067,S80G,0.007324998,0.027652312,0.020959051,-0.026581209,-0.060435341,-0.044996303,-0.01862526,0.033275256,-0.01419731,0.068639222,-0.013334599,0.015954886,0.025963216,0.001665742,-0.054828159,-0.005475071,-0.115395611,1.305254706,2.680820742,-5.03810191,-4.347550819,-6.180046425,-4.998769753,-4.287885101,-5.376257454,-5.572651789,-2.11475684 -1068,S80F,-0.021936472,0.049727858,-0.013782935,0.015995894,-0.022349997,-0.046772023,-0.040762226,-0.003110717,-0.034577581,0.088146972,0.011308743,0.043813201,-0.07137907,0.020868632,0.011123155,-0.016487452,-0.028212541,1.324682054,2.628936646,-6.360696454,-6.457349205,-8.382338104,-6.219138153,-4.836637421,-5.908019386,-6.812746309,-3.534824948 -1069,S80I,0.058598247,0.010656671,0.036695348,-0.019389035,-0.25249564,-0.121116769,0.048564033,0.068632461,-0.095654909,0.068755605,-0.047442263,0.07526501,-0.001874315,-0.005783563,-0.032994506,-0.216255127,-0.288736153,1.42893757,2.13258098,-6.298324435,-5.641306107,-6.815551735,-6.233091034,-5.528832367,-7.272840935,-7.397706917,-3.389731768 -1070,S80H,-0.004397067,0.072688406,0.035928497,0.01723173,0.034713463,-0.000986392,0.020030609,-0.028824742,0.027715976,0.168619086,-0.023242274,0.110018418,-0.038161424,0.058938089,-0.02447463,0.11218065,-0.042753724,1.07739216,2.92220415,-3.20298566,-1.987098755,-6.339782478,-3.476148361,-0.959738808,-3.252159897,-4.374581736,0.382901216 -1071,S80K,-0.057452679,-0.044111019,-0.164630083,-0.153568991,-0.065342318,-0.079027541,-0.100079365,-0.014825993,0.172029576,0.129712031,-0.217934068,-0.126262162,-0.202998003,-0.104070105,-0.203067876,0.018755069,-0.149439705,1.287897993,2.596848787,-3.330130141,-2.146525284,-5.587464272,-4.032521255,-2.288232735,-2.595907158,-3.189259936,0.695284114 -1072,S80M,-0.023645486,0.028413589,-0.010094269,0.003971601,-0.066786124,0.009913543,-0.098890094,0.051599122,0.017987373,0.056283113,0.000544065,0.034392127,-0.054580665,-0.015418477,0.023361678,-0.035650611,-0.097921637,1.323218227,2.490043386,-5.324362936,-4.538106705,-5.782431435,-6.135371407,-4.882769035,-5.283136101,-5.615595014,-2.340792165 -1073,S80L,-0.033878732,0.003233483,-0.00977208,-0.021265886,-0.017216283,-0.080803054,-0.052288021,-0.015469442,-0.035084031,0.087437818,-0.080970852,0.046162345,-0.065706504,0.038515577,-0.081047348,0.022042954,-0.05647552,1.203945648,2.756117793,-4.338200618,-3.712005524,-4.793232567,-4.782631912,-4.116888855,-4.286244232,-5.262522874,-1.358235053 -1074,S80N,-0.08671345,0.049912539,0.025657988,0.012276139,0.037980215,-0.023101176,-0.103804263,-0.069622637,0.030572228,0.146244266,-0.046419189,0.159330863,-0.108014888,0.166695654,-0.142143377,0.099507291,-0.023546861,1.068522011,2.96610325,-3.769201868,-2.951911552,-5.535278938,-4.531556114,-2.620296471,-3.206966263,-4.313887581,-0.324222475 -1075,S80Q,0.020450486,0.078464841,0.047844936,0.051442337,0.042273194,0.005134969,-0.012027286,0.052928257,-0.029723674,0.129502378,0.027427304,0.119402916,-0.023713045,0.087036203,0.015848471,0.104629267,-0.020082879,1.073022529,3.070684425,-3.529826997,-1.764112625,-6.569729691,-4.41730645,-1.632978477,-3.265007744,-3.38666574,0.905837643 -1076,S80P,-0.021013734,-0.22632506,-1.477347225,-1.953001366,-2.293021701,-0.012783471,-0.014290457,-0.02773701,-0.017278796,-0.106669068,-0.345981052,-1.360360729,-1.594333721,-1.68340233,-2.222600401,-1.842583915,-2.743459487,4.116280145,2.689273208,-7.774037581,-7.403420418,-8.542975616,-8.064102844,-7.209498573,-7.650190453,-9.046659553,-7.18566065 -1077,S80R,0.043912014,0.023830553,0.02109135,-0.00687618,0.006316882,-0.072262985,0.045482996,0.042341032,0.01229648,0.047712206,-0.0000511,0.037250681,0.004932019,0.019911584,-0.033663943,0.034362348,-0.021728584,1.216313162,2.80333895,-4.294402144,-3.115541458,-7.105670227,-4.96301696,-2.309520744,-3.97826133,-3.052766706,1.524557934 -1078,S80T,-0.021110906,-0.041997509,-0.009250742,-0.024874772,-0.022612891,-0.067392295,-0.018287052,-0.023934759,-0.012708157,-0.003439288,-0.080555729,-0.010567761,-0.007933723,0.005606262,-0.055355805,0.00065279,-0.045878572,1.163320143,2.519899511,-2.525990964,-2.48811644,-2.739701561,-2.717346558,-2.192399834,-2.492390427,-4.321798547,-1.148135986 -1079,S80W,-0.005498158,0.074824648,0.00672506,0.043488848,0.012556074,-0.135660192,-0.05538797,0.044391655,-0.093928877,0.160226389,-0.010577093,0.055581426,-0.042131306,0.116832211,-0.029854516,0.105383003,-0.080270855,1.079411031,2.92183514,-6.828069016,-6.330684547,-7.726988785,-7.298850975,-5.212383446,-7.571437325,-6.522338432,-2.791895324 -1080,S80V,-0.008756697,0.001130836,-0.021038003,-0.053764298,-0.081587569,-0.100935845,0.009251823,-0.026765216,-0.054204858,0.040672519,-0.038410848,-0.016725951,-0.025350054,-0.009834755,-0.097693841,-0.022315281,-0.140859856,1.19428499,2.477242401,-3.78905907,-3.484548889,-3.978569809,-3.989531593,-3.511034958,-3.9816101,-4.766424209,-1.871814991 -1081,S80Y,0.038575432,0.046273308,0.006748659,-0.029824102,0.040013894,-0.08489228,0.003971494,0.073179369,0.04097022,0.056007458,0.036539157,-0.00119747,0.014694787,-0.05283594,-0.006812264,0.001744103,0.078283685,1.198251489,2.629995888,-5.023483173,-4.383644653,-8.256493637,-5.101976379,-2.106969383,-5.26833181,-5.262635241,-1.387936311 -1082,R81A,-0.017815333,-0.01776894,-0.037088676,-0.021613384,-0.188147805,0.009769238,-0.066818644,0.031187978,-0.039554076,-0.001543443,-0.033994436,-0.023585909,-0.050591443,-0.034647541,-0.008579226,-0.185410058,-0.190885551,1.621299332,2.325708276,-6.800035385,-5.662657303,-6.267086578,-7.778174507,-7.584325661,-6.707932877,-5.924910882,-0.933494124 -1083,R81C,-0.027420629,-0.004582591,-0.031563928,-0.371294341,-1.624129056,0.102016297,0.001005894,-0.055847151,0.0163518,-0.016699436,0.007534255,-0.054521,-0.008606856,-0.221719879,-0.520868803,-1.690131812,-1.558126299,1.337254274,1.374435638,-9.70629068,-8.691199425,-10.29591684,-10.34909089,-9.532753937,-9.66249231,-7.304108984,-4.419697544 -1084,R81E,-0.018979202,-0.012774247,-0.03799178,-0.015531669,-1.466739053,0.068227587,-0.011197166,-0.026761238,-0.034149317,-0.054504919,0.028956425,-0.063556895,-0.012426665,-0.048918306,0.017854968,-1.495404654,-1.438073452,0.748324407,1.324960167,-6.38438447,-5.056917946,-7.019158951,-6.903066658,-7.142991837,-5.799786957,-5.324598647,-0.923295405 -1085,R81D,0.0000377,0.00793268,-0.03210496,-0.446090128,-1.581517669,-0.035873803,-0.010694901,0.010770299,-0.005869677,-0.031195233,0.047060592,-0.020556543,-0.043653377,-0.238710496,-0.653469759,-1.737491345,-1.425543993,1.350288875,1.368310013,-6.626249977,-4.281867355,-7.593464813,-5.950424011,-6.638147293,-8.667346413,-5.382875144,-1.156710177 -1086,R81G,-0.061778215,-0.028050445,-0.077628369,-0.043402497,-1.513572123,0.006583007,-0.08633876,-0.037217669,-0.021909969,-0.035025985,-0.021074904,-0.069222768,-0.086033969,-0.045869372,-0.040935622,-1.382198379,-1.644945867,0.826837131,1.338909674,-6.230447781,-6.390813652,-6.592454575,-6.83187487,-6.007526642,-5.329569168,-5.579214821,-2.178875398 -1087,R81F,0.059842322,0.068162342,0.025830263,0.001161222,-0.699796092,0.094903217,0.052666066,0.067018577,-0.099095094,0.027263447,0.109061237,-0.004547025,0.056207551,-0.053453357,0.055775801,-0.573211047,-0.826381136,1.359222778,1.692453448,-11.70878268,-9.998816872,-11.7766423,-12.72111183,-10.3204782,-13.72686418,-7.837640966,-4.27556118 -1088,R81I,-0.000672619,0.037720929,-0.046975253,-0.0584146,-1.42389794,0.027153488,-0.026017684,0.024672446,-0.070179215,-0.023855211,0.099297068,-0.028326112,-0.065624393,-0.054696961,-0.062132239,-1.165360713,-1.682435166,0.888948216,1.366223025,-10.75231271,-10.46017023,-10.48652612,-12.96393156,-9.663714577,-10.18722108,-8.527733181,-5.707633559 -1089,R81H,-0.085313828,-0.035217379,-0.101156614,-0.039854742,-0.321205933,0.001246909,-0.112464596,-0.05816306,-0.015215192,-0.032504758,-0.03793,-0.0455228,-0.156790427,-0.018971915,-0.060737568,-0.185042156,-0.45736971,1.238500805,2.015814537,-6.045845535,-6.433644714,-6.127481461,-6.044689903,-5.746162781,-5.877248817,-6.431439571,-3.055176 -1090,R81K,-0.043906191,-0.0666552,-0.052535839,-0.074443465,-0.051616291,-0.048374096,-0.05829417,-0.029518212,-0.044841456,-0.07595604,-0.057354359,-0.043955436,-0.061116242,-0.058836501,-0.090050429,-0.064151378,-0.039081204,1.334835492,2.373449504,-3.980805734,-4.303813393,-4.020109375,-3.635372589,-3.362663269,-4.582070045,-4.312134604,-0.824521954 -1091,R81M,-0.036461006,-0.031057745,-0.058285708,-0.087047375,-0.186559753,0.002318691,-0.105449437,0.032527425,-0.113624403,-0.014829525,-0.047285964,-0.017651552,-0.098919864,-0.072462026,-0.101632723,-0.136985182,-0.236134324,1.345279514,2.160178499,-8.79054639,-8.778355522,-8.485091591,-11.23664427,-7.553442245,-7.899198318,-6.680057505,-2.620263835 -1092,R81L,0.010610116,0.008759646,-0.022884489,-0.026334056,-0.179219629,-0.05354498,-0.006990693,0.028210924,-0.012710509,-0.026509479,0.04402877,-0.035876592,-0.009892386,-0.039205909,-0.013462203,-0.16088729,-0.197551968,1.458192345,2.233501817,-6.114860832,-5.912994293,-6.153731232,-8.853515739,-4.909612686,-4.744450211,-5.038215288,-1.378802938 -1093,R81N,-0.014860759,-0.042889953,-0.051431365,-0.07123174,-0.239244341,0.045580851,-0.043544014,0.013822497,0.007753888,-0.068746277,-0.017033629,-0.086719648,-0.016143081,-0.091111747,-0.051351733,-0.269564337,-0.208924344,1.54860694,2.093003216,-6.886143845,-6.066132339,-7.4382342,-6.621235268,-6.693255035,-7.611862381,-5.65073081,-3.170374201 -1094,R81Q,-0.075440842,-0.013630202,-0.041055384,-0.063627757,-0.215712484,0.014635173,-0.120500813,-0.030380871,-0.005751542,-0.018338911,-0.008921492,-0.015756527,-0.066354241,-0.073571796,-0.053683718,-0.21074081,-0.220684158,1.498079993,2.163044811,-4.171325552,-4.128810074,-4.421803307,-4.655102364,-4.47781218,-3.173099838,-4.897855894,-0.111195313 -1095,R81P,-0.01483925,-0.69609483,-1.963127629,-2.303597255,-3.062688981,0.020189225,-0.017343092,-0.012335408,0.052303868,-0.668372719,-0.723816941,-1.987376085,-1.938879172,-2.271392863,-2.335801647,-2.761573541,-3.36380442,1.542243778,-0.077424439,-12.05395426,-11.28890859,-12.19080585,-12.91754662,-11.75264608,-12.11986417,-10.47997372,-8.924126087 -1096,R81S,-0.058701185,-0.018177864,-0.047342122,-0.063619816,-0.725978424,0.018582156,-0.090715627,-0.026686742,0.036326305,-0.029540699,-0.006815029,-0.039176572,-0.055507671,-0.089006931,-0.0382327,-0.558122376,-0.893834471,2.637138447,2.802582299,-8.082844467,-7.68767189,-7.857932404,-8.149855293,-8.649837311,-8.068925438,-6.28861819,-3.10536493 -1097,R81T,-0.08529094,-0.034426002,-0.036001014,-0.016455654,-1.775995498,0.04017739,-0.087875708,-0.082706171,-0.002839185,0.008759449,-0.077611452,-0.007364546,-0.064637481,0.003016201,-0.035927508,-1.433776048,-2.118214947,0.749457069,1.328478104,-8.578649541,-7.802854584,-7.99684375,-8.750476944,-9.053988937,-9.289083488,-6.637558929,-3.444158613 -1098,R81W,-0.089748043,-0.010538217,-0.045731472,0.010094935,-1.456464756,0.002722894,-0.071251419,-0.108244666,0.000596738,0.029746319,-0.050822753,0.001332674,-0.092795618,0.059017517,-0.038827648,-1.582226414,-1.330703098,0.338832218,1.304335829,-10.58305488,-9.950487396,-11.05831363,-11.6150691,-9.473591599,-10.81781265,-7.966318982,-4.033403742 -1099,R81V,-0.052987957,-0.040181674,-0.054805575,-0.053949295,-1.659967983,0.022825508,-0.086713906,-0.019262007,-0.028455653,-0.020298015,-0.060065332,-0.006401751,-0.103209398,-0.031716881,-0.076181708,-1.417848297,-1.902087668,0.817553916,1.335688426,-9.648307803,-8.572995628,-9.30253653,-11.75603367,-9.166711998,-9.443261192,-7.673170004,-4.873921903 -1100,R81Y,-0.031394298,-0.003046713,-0.0157521,-0.006147488,-0.680618794,-0.019064964,-0.050582142,-0.012206453,-0.029537555,-0.004107189,-0.001986237,-0.042051641,0.010547442,-0.019286094,0.006991118,-0.635358954,-0.725878633,0.849181324,1.447754335,-11.56392999,-11.4936092,-12.70887596,-11.64326144,-10.2718342,-11.70206918,-8.050760456,-2.897884873 -1101,V82A,0.02364608,0.00657732,0.022050464,0.010293498,-0.115991508,0.049146985,0.04257509,0.00471707,0.040949753,0.019986003,-0.006831363,0.023909008,0.02019192,0.00474556,0.015841436,-0.096319181,-0.135663835,1.302304122,2.266527397,-4.647400261,-3.408050621,-4.909441437,-3.566066582,-5.317224648,-6.036218018,-2.267512075,-0.787048559 -1102,V82C,-0.012873497,-0.00978831,0.001146796,0.001306052,-0.161156887,0.07720748,-0.022516196,-0.003230798,-0.009759837,0.035038741,-0.05461536,0.037105801,-0.03481221,0.037451523,-0.034839419,-0.086343059,-0.235970714,1.458823433,2.599113206,-9.147447333,-6.947304535,-9.09932254,-9.024100281,-10.51731407,-10.14919524,-5.475818752,-4.047848571 -1103,V82E,-0.059003196,0.053682252,-0.002924168,-0.096081564,-1.894693829,0.077585552,-0.016096831,-0.101909561,0.174300351,0.01900518,0.088359324,-0.022771613,0.016923277,-0.026206074,-0.165957053,-1.685408872,-2.103978786,0.839385899,1.319649814,-9.44456954,-9.024781723,-8.923182022,-8.439155861,-8.446253319,-12.38947478,-5.451898495,-3.528226316 -1104,V82D,-0.078538422,-0.069542888,-0.058260386,-0.791423154,-1.850754,0.029783281,-0.071522892,-0.085553952,0.013721259,-0.055964568,-0.083121207,-0.047862265,-0.068658506,-0.558429747,-1.02441656,-1.71252529,-1.988982709,1.941869632,1.553586766,-10.15743529,-9.583403831,-7.125161446,-9.646863174,-10.81224039,-13.61950761,-5.117557733,-3.392225889 -1105,V82G,-0.040222061,-0.006271679,-0.031501978,-0.138420779,-1.77800061,0.071442501,-0.013028369,-0.067415753,-0.221566649,-0.004367659,-0.008175698,-0.037897592,-0.025106364,-0.064625388,-0.212216169,-1.584244913,-1.971756307,0.752884442,1.320207154,-9.676449419,-10.06672876,-9.425390625,-7.787416611,-8.633965309,-12.46874579,-4.254121747,-3.499390659 -1106,V82F,-0.031345183,-0.007771254,-0.039456959,-0.020351679,-1.633488879,0.032345099,0.003313491,-0.066003856,0.104183515,0.00012154,-0.015664047,-0.013172891,-0.065741027,-0.005633079,-0.035070279,-1.50128468,-1.765693077,0.586450482,1.31512768,-11.0659356,-11.07965033,-11.01479855,-9.10072644,-9.669673569,-14.46482912,-6.019152891,-3.189714044 -1107,V82I,-0.018774182,0.014332529,-0.004298984,-0.012213768,-0.067475422,0.041422819,0.00141366,-0.038962024,0.020203386,0.045709423,-0.017044366,0.023198406,-0.031796374,0.017611902,-0.042039438,-0.046753136,-0.088197708,1.213343559,2.398956387,-3.379468724,-3.330043068,-2.793114372,-3.239265663,-3.891975174,-3.642945343,-1.701087353,-1.168657654 -1108,V82H,-0.023783006,-0.040903918,0.004089641,-0.044471661,-0.512638539,0.092888544,-0.013847672,-0.033718339,-0.018741136,-0.002348656,-0.079459179,-0.024465058,0.03264434,-0.000275242,-0.08866808,-0.346971627,-0.678305451,0.855719929,1.567655404,-9.467669061,-9.169349709,-8.645125046,-9.460372177,-7.645638153,-12.41786022,-4.46330427,-2.680930702 -1109,V82K,-0.041214193,0.019099755,-0.027513819,-0.027753198,-1.543739055,0.060878349,-0.025113066,-0.057315319,0.388180171,0.035380288,0.002819221,-0.039501049,-0.015526588,0.000949794,-0.05645619,-1.632879309,-1.454598801,0.72628651,1.315630519,-8.873556502,-9.74367495,-8.512688156,-8.347307198,-6.949787697,-10.81432451,-3.987403751,-3.477587174 -1110,V82M,-0.068743266,-0.012698854,-0.01737977,-0.04834492,-1.392685652,0.072471692,-0.020541655,-0.116944876,-0.126729644,0.042770717,-0.068168425,0.014050816,-0.048810356,-0.001215627,-0.095474213,-1.406849128,-1.378522175,0.648782928,1.322662941,-8.47711888,-8.170028397,-8.728244576,-7.295127853,-7.146078285,-11.04611529,-5.409819682,-3.230782262 -1111,V82L,-0.052796091,0.010679284,-0.024765829,-0.077961666,-1.847136171,0.11714804,-0.022602368,-0.082989813,0.00428324,-0.003998797,0.025357364,-0.020066959,-0.029464698,-0.038125001,-0.11779833,-1.659532143,-2.034740199,0.759445048,1.316529467,-6.894863853,-7.161237907,-7.35237542,-6.122658012,-5.122457077,-8.715590851,-3.778675433,-1.922032592 -1112,V82N,-0.047923674,0.004200988,-0.004557653,-0.021605915,-2.000244548,0.081369188,-0.039049658,-0.056797689,-0.037788561,0.036353376,-0.027951401,-0.003224453,-0.005890853,-0.013352646,-0.029859183,-1.424794087,-2.575695008,0.69210085,1.324587508,-9.815535733,-9.760730774,-9.20993589,-8.805533226,-8.534450829,-12.76702795,-4.542852859,-2.636820663 -1113,V82Q,0.0168214,0.025459227,0.012456552,0.031384089,-1.472826012,0.059906694,0.043896261,-0.010253461,0.001235547,-0.049291389,0.100209843,-0.006590596,0.0315037,0.039168805,0.023599372,-1.443618957,-1.502033067,0.705085727,1.324073152,-7.719080127,-8.13672583,-7.440542206,-6.948573471,-6.264174324,-9.805384804,-4.878196286,-4.043456638 -1114,V82P,-0.060577883,-0.444607139,-1.805983155,-2.313036301,-2.960805997,0.066681031,-0.045552041,-0.075603725,-0.015154869,-0.348339794,-0.540874483,-1.729608552,-1.882357757,-2.086410972,-2.539661629,-2.589841189,-3.331770804,2.898189882,1.123066537,-12.06667736,-11.55962688,-11.63977038,-11.39539185,-11.51399146,-14.22460622,-7.130731584,-6.410174892 -1115,V82S,-0.013675603,-0.017376661,-0.024745926,-0.020762809,-0.654394682,0.065393824,0.005723694,-0.0330749,0.030088794,-0.007746736,-0.027006586,-0.028954336,-0.020537515,-0.025118663,-0.016406954,-0.450547638,-0.858241726,1.17377588,1.666055242,-7.909236185,-6.307212875,-8.508007462,-6.696260139,-7.11675856,-10.91794189,-3.533072753,-1.829132703 -1116,V82R,-0.012756504,0.014615684,-0.008757603,-0.016316637,-1.538348341,0.073547866,0.015530325,-0.041043333,0.073139461,0.004136941,0.025094427,-0.029440593,0.011925388,-0.035566613,0.00293334,-1.409227671,-1.66746901,0.823614571,1.336048864,-8.512771008,-8.73029496,-8.85192524,-9.373841057,-5.716705711,-9.891088074,-4.416342965,-2.744201076 -1117,V82T,-0.052854029,-0.021538878,-0.01449999,-0.01136095,-0.458571735,0.087370302,-0.022969604,-0.082738454,-0.208127491,0.023438956,-0.066516712,0.01566734,-0.044667319,-0.002291039,-0.020430861,-0.348260726,-0.568882743,0.968915868,1.644018406,-7.23696767,-6.561363617,-6.701391678,-6.385270432,-7.557248085,-8.979564537,-4.389713005,-2.836076644 -1118,V82W,-0.000279048,0.034775789,-0.010688762,-0.00051615,-1.504499223,0.033329728,0.012673876,-0.013231971,-0.14693303,0.021637745,0.047913832,0.02195761,-0.043335133,-0.015612948,0.014580649,-1.294401516,-1.714596929,0.794965875,1.34204934,-11.88271622,-11.70707121,-12.24678862,-10.80878152,-10.6539921,-13.99694765,-7.065927138,-6.523346105 -1119,V82Y,-0.100965825,-0.068454665,-0.060176226,-0.059228178,-1.331138427,0.006738443,-0.097752696,-0.104178954,0.087150176,-0.001023239,-0.13588609,-0.013939246,-0.106413206,-0.035440396,-0.08301596,-0.968995306,-1.693281547,0.888955534,1.389953297,-11.88190003,-11.32664417,-11.14407112,-10.08856184,-10.84800731,-16.00221573,-5.330620742,-3.288971544 -1120,D83A,-0.143561675,-0.077570233,-0.043032293,-0.082331328,-1.691802754,0.006720323,-0.117421006,-0.169702343,0.013509291,-0.030007764,-0.125132702,-0.017870126,-0.068194459,-0.030963038,-0.133699617,-1.530732881,-1.852872627,0.59473498,1.313506819,-8.519157535,-6.152644264,-8.595246208,-12.61904709,-6.224148727,-9.004701386,-4.721784029,-1.446622053 -1121,D83C,-0.118593263,-0.088734772,-0.022321829,-1.384641764,-2.688763922,0.076148557,-0.088627235,-0.14855929,-0.021465398,-0.094063136,-0.083406408,-0.019283795,-0.025359862,-1.234441939,-1.534841588,-2.171129604,-3.20639824,2.274892404,1.470178547,-13.89365689,-11.69398572,-14.1157723,-18.0742255,-12.02309994,-13.56120098,-9.177172791,-6.657912106 -1122,D83E,-0.009370508,-0.002254833,0.04483406,-0.005885425,-0.096051752,0.015333734,-0.019521708,0.000780693,0.01627343,0.024349898,-0.028859563,0.056725391,0.032942728,-0.017884594,0.006113745,-0.092954356,-0.099149148,1.273871112,2.314091754,-4.65389301,-3.583685799,-4.621085953,-7.125994308,-4.160987114,-3.777711876,-4.141857461,-0.83423194 -1123,D83G,-0.073048334,-0.050513363,-0.026441369,-0.10738702,-1.86508199,0.056989478,-0.075360657,-0.07073601,-0.062158256,-0.022319019,-0.078707706,-0.015416006,-0.037466731,-0.078314216,-0.136459823,-1.668188726,-2.061975253,0.808562394,1.318748343,-9.050316156,-6.476024727,-9.44026255,-12.43665324,-7.560489067,-9.338151192,-6.669162387,-3.191356227 -1124,D83F,-0.100942685,-0.05938765,-0.693523178,-1.763186097,-2.7042285,-0.031874635,-0.053523813,-0.148361557,-0.067506537,-0.056850945,-0.061924355,-0.481617704,-0.905428652,-1.806536775,-1.719835418,-2.518284614,-2.890172386,1.714657734,0.812253335,-14.83520027,-13.2245118,-14.54475845,-19.77143609,-13.35689011,-13.27840491,-8.714902588,-5.54722907 -1125,D83I,-0.063191356,-0.074352493,-0.078379838,-1.624806584,-2.016937309,-0.050926484,-0.076211955,-0.050170757,-0.109303454,-0.093428941,-0.055276044,-0.03394733,-0.122812346,-1.508007454,-1.741605713,-2.051350862,-1.982523755,1.264451243,0.775584791,-14.28678784,-13.83390658,-13.79460052,-18.30379232,-11.19114969,-14.31049007,-8.226362598,-5.824854521 -1126,D83H,-0.040206122,-0.021761913,0.014776724,-0.89984618,-2.269238258,0.028223766,-0.045361045,-0.035051199,-0.020002774,-0.052112566,0.008588741,-0.012141029,0.041694476,-0.661979834,-1.137712525,-1.937293507,-2.601183008,1.778420294,1.387911765,-8.782961143,-7.062699951,-8.289400185,-11.9476874,-6.671564697,-9.943453484,-6.451487386,-3.129245958 -1127,D83K,-0.066975436,-0.062170926,0.015089411,-0.778854708,-2.194756062,-0.014355165,-0.054376851,-0.079574021,-0.026359147,-0.066882982,-0.057458869,-0.003928095,0.034106917,-0.494729312,-1.062980103,-1.895307523,-2.4942046,1.70283385,1.413213416,-9.779066435,-7.842997391,-9.531024261,-13.81035509,-8.239339233,-9.471616196,-6.631604959,-2.467816243 -1128,D83M,-0.224109144,-0.042628952,-0.011138499,-1.053161372,-1.688388499,-0.034895092,-0.000627996,-0.447590291,-0.072682259,-0.049474707,-0.035783196,-0.032274267,0.009997269,-0.832414908,-1.273907836,-2.034647962,-1.342129035,2.182409577,1.557187964,-13.53412581,-12.95069685,-13.18175354,-17.60739271,-10.87182018,-13.05896579,-7.001499838,-3.756477765 -1129,D83L,-0.051338605,-0.054474568,-0.234739452,-1.557010919,-2.734828189,-0.074519116,-0.060754964,-0.041922245,0.009934126,-0.05093954,-0.058009596,-0.144246348,-0.325232556,-1.488490555,-1.625531282,-2.401883757,-3.067772621,1.078478698,0.743853528,-13.25972813,-12.93115707,-12.94427644,-17.68989948,-10.22863145,-12.5046762,-6.708215899,-4.115099478 -1130,D83N,-0.006401794,-0.023130018,-0.010393307,-0.091371292,-2.019126225,0.068659931,0.00041739,-0.013220978,0.122630008,-0.022490892,-0.023769143,0.010401968,-0.031188582,-0.09853483,-0.084207754,-1.64263949,-2.395612959,0.949301989,1.330980288,-8.325561273,-6.723494591,-7.318970222,-10.52313324,-7.812162979,-9.250045334,-6.763334443,-3.163439021 -1131,D83Q,-0.050964392,-0.060644755,-0.007093007,-0.034668355,-0.307681489,0.049741424,-0.054026253,-0.04790253,0.008411671,-0.04916627,-0.072123239,0.031045121,-0.045231134,-0.023164475,-0.046172235,-0.258154029,-0.357208949,1.184503074,1.828495987,-8.491979831,-6.638057159,-8.752480621,-11.25586845,-7.513218628,-8.3002743,-5.000106645,-2.026122101 -1132,D83P,-0.045632229,-0.04578213,-1.107685106,-1.869660889,-2.944289156,0.080392476,-0.042558857,-0.048705601,0.01024835,-0.03603298,-0.05553128,-1.021010614,-1.194359598,-1.822325786,-1.916995991,-2.722064107,-3.166514205,2.403499216,1.093923145,-11.95670678,-7.556582855,-12.70277243,-16.56848303,-11.25630791,-11.69938768,-5.638249076,-2.437532398 -1133,D83S,-0.071765283,-0.054451769,-0.007096241,-0.048088055,-1.653496975,0.060788668,-0.058814077,-0.084716489,0.024441848,-0.053338178,-0.05556536,-0.005111203,-0.009081278,-0.041785833,-0.054390277,-1.454932169,-1.852061781,0.582119371,1.316706729,-9.400484158,-6.341538185,-9.508948952,-13.45557604,-8.23358873,-9.462768883,-5.763813821,-1.818745924 -1134,D83R,-0.059269045,-0.054055986,-0.014104799,-1.167210791,-2.109991013,0.021319551,-0.069524413,-0.049013677,-0.027924746,-0.043460468,-0.064651503,-0.015654635,-0.012554962,-0.848859399,-1.485562182,-2.053103354,-2.166878672,2.028604267,1.454498099,-8.791749467,-8.729455292,-6.804651825,-11.9097956,-7.370089973,-9.144754646,-5.514707105,-2.391647065 -1135,D83T,-0.121552342,-0.066930593,-0.017447223,-0.159290823,-1.742747116,0.064186385,-0.025454888,-0.217649796,-0.02237912,-0.060446753,-0.073414432,-0.032360832,-0.002533613,-0.130702218,-0.187879428,-1.692576649,-1.792917582,0.883727947,1.321358139,-10.39226464,-7.58237458,-11.14175458,-14.72469881,-7.378234192,-11.13426103,-6.491447456,-2.7676608 -1136,D83W,-0.048484868,-0.058698985,-0.80763949,-1.92369875,-2.996894747,-0.03183439,-0.044640554,-0.052329181,-0.017897527,-0.040197128,-0.077200841,-0.748996198,-0.866282782,-1.883100753,-1.964296746,-2.719787328,-3.274002166,2.02523711,0.891066295,-13.78739878,-12.60462251,-12.54378258,-18.12429844,-12.50774976,-13.15654062,-8.640079494,-5.882583966 -1137,D83V,-0.194687721,-0.043709894,0.00433854,-1.191333474,-1.970337587,0.068547263,-0.041454931,-0.347920511,-0.044843708,-0.082044122,-0.005375665,-0.009818369,0.018495448,-0.925719553,-1.456947394,-1.932745058,-2.007930115,2.292506093,1.632725172,-11.96765676,-11.60577998,-11.36696789,-15.98356109,-8.87623877,-12.00573608,-6.386846036,-3.516900655 -1138,D83Y,-0.081532647,-0.042175975,-0.247448463,-1.858446232,-2.889481787,0.061175584,-0.106669741,-0.056395552,-0.067497575,-0.057920317,-0.026431633,-0.140994643,-0.353902283,-1.5197033,-2.197189164,-2.930421142,-2.848542431,1.137069645,0.751699023,-13.7126861,-11.46433321,-14.88670873,-17.7519307,-12.77996906,-11.68048882,-8.263954348,-4.720137402 -1139,A84C,0.008774747,0.01381661,0.023578695,-0.012594668,-0.438931888,0.078524336,-0.012519162,0.030068655,-0.052781211,-0.003072324,0.030705543,0.06258254,-0.015425151,-0.012960788,-0.012228548,-0.327870542,-0.549993233,1.028906061,1.673434527,-6.414064891,-5.184808876,-7.555640228,-6.472646484,-5.973818954,-6.883409912,-7.05757314,-4.599009324 -1140,A84E,0.112527629,0.050621837,-0.017094731,0.016002861,-0.0000234,-0.019062756,0.151369934,0.073685323,0.103381615,-0.034314774,0.135558448,-0.063545654,0.029356192,-0.009165286,0.041171008,-0.126622498,0.126575647,1.383604708,2.246476384,-2.665904166,-1.4761604,-3.562977394,-4.179887238,-1.925609177,-2.18488662,-4.22914663,-0.850942185 -1141,A84D,0.016112201,-0.011320309,0.028974468,0.037160109,-0.005715479,0.039745903,0.04070601,-0.008481609,0.064345175,-0.031119888,0.008479271,0.060688494,-0.002739558,0.025768941,0.048551277,-0.051240785,0.039809827,1.339562443,2.506177327,-3.614593571,-2.358720139,-4.024892052,-4.492796173,-3.458454063,-3.738105431,-4.706804491,-1.775913975 -1142,A84G,-0.008743023,-0.009919053,0.030297803,0.010604095,-0.024581986,0.028956292,-0.014665587,-0.002820458,-0.000531044,-0.002879435,-0.01695867,0.055663413,0.004932192,-0.005586686,0.026794875,-0.027716017,-0.021447955,1.184913061,2.456388285,-4.111107759,-2.691604599,-4.808729004,-3.964761978,-4.574019615,-4.516423599,-5.287182914,-2.908204527 -1143,A84F,0.026800011,0.008507744,0.04761136,0.014222851,-0.186143212,0.056387382,0.033728957,0.019871065,-0.008342517,-0.017702443,0.03471793,0.048546126,0.046676593,-0.008500129,0.036945831,-0.214600446,-0.157685977,1.416943555,2.098464661,-9.742337299,-6.886958412,-11.34148347,-10.06908424,-9.157087151,-11.25707323,-9.386055015,-8.771873457 -1144,A84I,0.037544266,0.031125493,0.046374314,0.030265533,-0.013374837,0.047745806,0.017706332,0.0573822,-0.030804663,0.033809134,0.028441851,0.058137828,0.0346108,0.046066204,0.014464862,-0.036157277,0.009407603,1.381934168,2.678932206,-5.435155228,-3.36135144,-6.857830795,-5.092120918,-5.079789482,-6.784683502,-5.840283682,-3.586981477 -1145,A84H,0.02273299,-0.005790822,0.03668153,0.027081882,-0.000873553,0.004769037,-0.005714326,0.051180305,0.177709354,0.024025791,-0.035607435,0.071683226,0.001679834,0.028945254,0.02521851,0.012058979,-0.013806085,1.543610422,3.106887046,-4.270264594,-2.596909622,-5.107809273,-4.822845543,-4.561553925,-4.262204605,-5.161538318,-2.412939445 -1146,A84K,0.058455078,0.033255941,0.070427992,0.046430811,0.027428182,0.045141214,0.045570164,0.071339992,-0.043726674,0.044180667,0.022331214,0.092782456,0.048073528,0.056995298,0.035866324,0.025310252,0.029546112,1.034682754,2.555993639,-1.795460637,-0.88035511,-2.316403687,-2.77899839,-2.25850515,-0.743040848,-3.615480533,-0.714219381 -1147,A84M,0.02976156,0.002512851,0.046822681,0.023207642,-0.009573927,0.023854439,0.026701981,0.032821138,0.018908324,-0.004839512,0.009865213,0.028389659,0.065255703,0.009703196,0.036712088,-0.032788796,0.013640943,1.327300781,2.555607532,-6.478755859,-4.909011314,-8.184231102,-6.796018959,-6.025733704,-6.478784218,-6.688696472,-4.630778688 -1148,A84L,0.038657231,-0.002348847,0.053646807,0.039411722,0.005085066,0.03857616,0.039297025,0.038017436,-0.028634598,-0.01397469,0.009276996,0.040510951,0.066782663,0.02497658,0.053846863,-0.035698872,0.045869003,1.153938629,2.386782976,-5.273322597,-2.571635612,-7.31011277,-5.772872871,-4.77225367,-5.93973806,-5.483421738,-2.178117913 -1149,A84N,0.06960399,0.034260571,0.060363623,0.042273861,0.037337985,0.061537134,0.076766182,0.062441798,-0.002620552,0.008452504,0.060068637,0.074324158,0.046403087,0.031963674,0.052584047,0.003554374,0.071121596,1.188288169,2.630149916,-2.848383533,-2.115461937,-3.180437172,-3.194479065,-3.285868141,-2.465671349,-4.767754692,-2.053582197 -1150,A84Q,0.047819917,0.058947878,0.061433796,0.042319706,0.02005532,0.02742766,0.043594573,0.05204526,-0.046997672,0.112744428,0.005151328,0.070788821,0.05207877,0.037261067,0.047378344,0.022019207,0.018091432,1.179151542,2.724074304,-1.892163843,-0.619951653,-2.269922989,-2.753637184,-2.360191345,-1.457116043,-3.326610818,-0.791436696 -1151,A84P,-0.023263699,-0.013467298,-0.038051462,-1.563208104,-2.360139618,0.092560235,-0.006461781,-0.040065616,0.067347066,-0.014019996,-0.012914599,0.005180692,-0.081283615,-1.398879891,-1.727536317,-2.204493871,-2.515785365,0.732938674,0.714934894,-6.613263507,-5.107170921,-7.407126511,-7.281639671,-6.185678345,-7.084702087,-6.952731985,-4.879590906 -1152,A84S,0.029124966,-0.004853581,0.034941138,0.02733236,0.012671526,0.021777934,0.021262958,0.036986973,-0.034898738,-0.033794689,0.024087527,0.049350273,0.020532002,0.013592873,0.041071847,-0.012541746,0.037884798,1.288598056,2.687595151,-2.03665835,-1.270673996,-2.037686455,-2.070626808,-2.374715752,-2.429588737,-3.963402228,-1.544413971 -1153,A84R,0.059796684,0.014987,0.055523469,0.041662099,0.016879106,0.002524427,0.056410353,0.063183014,-0.039179667,0.008457592,0.021516408,0.045330199,0.065716739,0.018296946,0.065027252,-0.01313214,0.046890352,1.114053806,2.46394564,-2.201205472,-0.777942863,-3.056467209,-2.989908173,-2.273754372,-1.907954742,-4.059759785,-0.383069447 -1154,A84T,0.012935652,-0.0026622,0.042518823,0.020981884,-0.01452706,0.053745618,0.020620332,0.005250972,0.015256666,-0.001601442,-0.003722957,0.035022439,0.050015206,0.014545467,0.027418301,-0.039540333,0.010486214,1.31932374,2.550777895,-2.436505905,-1.884270805,-2.362613411,-2.192047783,-2.674392639,-3.069204887,-4.509298514,-1.840575445 -1155,A84W,0.013481052,0.027025544,0.041726408,0.037018367,-0.395755631,0.053858027,0.012731373,0.014230731,-0.007935482,0.035125746,0.018925341,0.072786893,0.010665923,0.070434078,0.003602656,-0.275654079,-0.515857183,1.383502477,2.021567747,-8.660062907,-6.412333168,-10.0998651,-8.99853418,-8.238330864,-9.551251228,-8.345260108,-6.622117527 -1156,A84V,0.020949721,0.0029622,0.007884576,0.041511479,-0.020480268,0.065518442,0.00844634,0.033453101,0.015432886,-0.013781203,0.019705602,0.029632972,-0.013863821,0.033212726,0.049810231,-0.044137489,0.003176954,1.368030563,2.636979071,-4.840387595,-3.395909119,-6.2883246,-4.171610519,-4.577073227,-5.769020508,-5.2737693,-3.512611944 -1157,A84Y,0.008516349,-0.003343181,-0.005425017,0.031171412,-0.150514537,0.081910934,0.002192823,0.014839875,-0.038725146,-0.004800118,-0.001886244,0.028699593,-0.039549627,0.010116712,0.052226111,-0.161804396,-0.139224677,1.448061782,2.238368622,-7.326366263,-4.669548775,-8.978424103,-7.507943794,-6.907978554,-8.567936089,-6.623514561,-4.225877116 -1158,G85A,-0.045494527,0.005673465,-0.004675723,-0.02002461,-0.134062149,0.011551997,-0.057938535,-0.033050519,0.055082083,-0.012872829,0.024219759,-0.00371771,-0.005633735,-0.045680644,0.005631424,-0.114959144,-0.153165153,1.23583949,2.142959763,-4.970801604,-4.923278427,-5.277532082,-6.17622168,-4.890285637,-3.586690193,-4.815866686,-4.215600771 -1159,G85C,-0.067626919,0.016737244,-0.0384789,-0.045145997,-1.402625032,0.05800635,-0.075561441,-0.059692396,0.190041181,-0.042646283,0.07612077,-0.019954096,-0.057003703,-0.035624324,-0.054667669,-1.238052925,-1.567197139,0.842010044,1.351381989,-7.583537041,-6.810353958,-7.899863777,-8.976203178,-6.612146507,-7.619117783,-7.462001985,-6.134910324 -1160,G85E,-0.04912052,0.026280801,-0.007104728,-0.023936674,-0.088473564,0.026864835,-0.056829407,-0.041411632,0.144736553,0.003427628,0.049133973,-0.026336731,0.012127276,-0.036793574,-0.011079773,-0.114638789,-0.062308338,1.505411973,2.394398974,-5.281595103,-5.09466008,-4.939381897,-7.186698029,-4.05875148,-5.128484032,-4.877804873,-3.20831146 -1161,G85D,-0.056540105,-0.063261732,-0.049051681,-0.045090129,-0.106921018,0.038850183,-0.030706575,-0.082373634,0.232151116,-0.005545258,-0.120978205,-0.007314593,-0.090788768,-0.048724085,-0.041456172,-0.087078791,-0.126763244,1.364189641,2.335292185,-5.277745706,-4.498427521,-4.515184608,-7.504985405,-3.924901749,-5.945229248,-4.729393883,-2.479800896 -1162,G85F,0.029152246,0.038798721,0.011852151,-0.003773596,-0.615544979,0.010589737,0.002068819,0.056235673,0.067676152,0.018356261,0.05924118,0.018218181,0.00548612,-0.015916751,0.00836956,-0.559543385,-0.671546573,0.979244007,1.519084357,-9.860517162,-8.76168885,-10.76290843,-11.19643118,-8.416792053,-10.16476529,-9.186646766,-10.17688797 -1163,G85I,0.015318501,0.035779289,-0.001290188,-0.199866711,-1.531599286,0.074549026,0.025537028,0.005099973,0.171981775,-0.05664302,0.128201597,-0.051904676,0.0493243,-0.170623343,-0.229110079,-1.643132804,-1.420065768,1.140786462,1.352639697,-9.193322557,-7.937546707,-10.29889357,-10.5130658,-7.526443504,-9.6906632,-7.680020476,-7.08504776 -1164,G85H,-0.010170774,-0.010804266,-0.046503315,-0.039984248,-0.051679096,-0.069309183,-0.063053687,0.04271214,0.125281636,-0.017018927,-0.004589604,-0.025378593,-0.067628037,-0.064382016,-0.015586479,-0.057251171,-0.046107021,1.405395516,2.450834117,-5.764833196,-5.03192424,-6.55672007,-6.691097038,-4.786579185,-5.757845444,-5.058254541,-3.979909224 -1165,G85K,-0.0062984,0.03045023,-0.000854231,-0.038739607,-0.033350538,-0.021819678,-0.021804072,0.009207272,0.090010349,-0.013245934,0.074146394,-0.020786218,0.019077756,-0.047550675,-0.029928538,-0.061938945,-0.00476213,1.235614592,2.316205312,-3.638664856,-2.82105101,-3.845787033,-4.947062103,-3.086270966,-3.493153168,-3.787463349,-2.9761541 -1166,G85M,-0.029473892,0.031363942,-0.014045542,-0.024594839,-0.186685881,0.025720771,-0.058357623,-0.000590161,0.105030392,-0.013784979,0.076512862,-0.002833688,-0.025257396,-0.046899424,-0.002290254,-0.161205531,-0.212166231,1.469862864,2.251062208,-8.223594408,-7.057010231,-9.171116394,-9.619933357,-6.936675888,-8.333236168,-7.316257679,-6.587449024 -1167,G85L,-0.057280909,0.018847409,-0.00990461,-0.031534822,-0.424891033,0.055974327,-0.070847705,-0.043714113,0.123635323,-0.007331888,0.045026706,-0.003183999,-0.016625221,-0.04238674,-0.020682904,-0.374399593,-0.475382472,1.315392613,1.814269891,-7.740498155,-6.512463142,-8.906674469,-8.98989608,-6.202539268,-8.090917816,-6.671122375,-5.9947101 -1168,G85N,-0.006804173,-0.038492386,-0.023017627,-0.013579932,-0.076674709,-0.006625207,-0.03638781,0.022779464,0.237828249,-0.040351158,-0.036633613,-0.032603912,-0.013431341,-0.073011449,0.045851585,-0.106606295,-0.046743123,1.363723155,2.254357076,-4.365600484,-3.910720848,-4.397990288,-5.877980286,-3.871985039,-3.769325958,-4.564714529,-3.032910436 -1169,G85Q,-0.023386707,0.011642429,0.004937038,-0.017618004,-0.025383443,-0.008512774,-0.052286955,0.005513542,0.101471158,-0.025219188,0.048504045,0.015462004,-0.005587929,-0.046284876,0.011048869,-0.05312828,0.002361395,1.268116262,2.337758239,-5.184446939,-4.534344376,-6.053871704,-6.138254997,-4.353173233,-4.842590385,-4.537664691,-3.430987942 -1170,G85P,-0.076432019,-0.073465251,-1.355532061,-2.145045111,-2.908875342,0.015316943,-0.066059386,-0.086804652,0.167450749,-0.016924125,-0.130006376,-1.2721139,-1.438950221,-2.023744173,-2.266346048,-2.751144509,-3.066606175,2.366541,0.928534959,-8.436407391,-7.892549789,-8.897169891,-9.590136047,-7.730106972,-8.072074257,-7.93289289,-7.08504787 -1171,G85S,-0.033985428,-0.001685295,-0.031968005,-0.027776754,-0.164970784,-0.011824446,-0.048477234,-0.019493622,0.090579814,-0.029448344,0.026077755,-0.029067773,-0.034868236,-0.043249126,-0.012304382,-0.172184374,-0.157757193,1.434172927,2.191746645,-5.244926497,-5.034703766,-5.329752853,-6.322916916,-5.505439095,-4.031819855,-5.403009221,-4.03245545 -1172,G85R,-0.050108416,0.005366736,-0.024332338,-0.031185887,-0.1023798,0.014703173,-0.055652151,-0.04456468,0.119362392,-0.005105665,0.015839137,-0.011814427,-0.036850249,-0.026155582,-0.036216192,-0.100630326,-0.104129274,1.453623291,2.403376724,-4.997319452,-4.016695465,-6.023374649,-5.952515419,-3.620424492,-5.373587235,-4.878773333,-3.451941563 -1173,G85T,-0.083054492,-0.022286671,-0.029338823,-0.051329989,-1.282214244,0.049189183,-0.08523439,-0.080874593,0.147091687,-0.02350772,-0.021065622,-0.009601425,-0.049076221,-0.042263032,-0.060396945,-1.140289161,-1.424139327,0.659829284,1.339298508,-6.297128513,-5.6832192,-6.95415818,-7.038778946,-5.765471893,-6.044014343,-5.786376892,-4.814866977 -1174,G85W,-0.048077875,0.034556368,-0.007826867,-0.007125138,-1.596722025,0.085441888,-0.042624052,-0.053531697,0.131527655,-0.00306906,0.072181795,-0.002478237,-0.013175497,-0.009351987,-0.004898289,-1.581319765,-1.612124285,0.670212756,1.318099578,-9.222419188,-7.888699211,-9.379488853,-10.76473759,-8.083603653,-9.995566628,-8.144355623,-7.748490008 -1175,G85V,-0.061125331,-0.002129729,-0.02687701,-0.044892332,-1.542004165,0.021949445,-0.053576684,-0.068673977,0.08325443,-0.029124131,0.024864674,-0.015270649,-0.03848337,-0.021715933,-0.068068731,-1.607405625,-1.476602705,0.769272184,1.31963984,-8.010738562,-6.866942184,-8.940439079,-9.345921883,-7.211634285,-7.688755379,-6.685152382,-5.403878074 -1176,G85Y,-0.04462753,-0.022910234,0.001453778,-0.050571971,-0.794174256,-0.026840877,-0.066831562,-0.022423498,0.011931118,-0.040263047,-0.00555742,0.014483895,-0.011576339,-0.07711136,-0.024032581,-0.545222757,-1.043125754,1.689468211,1.950664742,-8.647571689,-7.601936867,-9.282961617,-9.912909897,-7.23850341,-9.201546654,-7.286611438,-6.688132427 -1177,Q86A,0.010585303,-0.054818768,-0.03879968,-0.008917203,-0.031346184,0.014052771,0.012010375,0.009160231,-0.018123461,-0.054414619,-0.055222917,-0.027080872,-0.050518487,-0.013683558,-0.004150847,0.010314101,-0.073006469,1.322377976,2.673405999,-2.752754758,-2.89783725,-2.209007782,-2.425049072,-3.494519669,-2.737360016,-3.100654148,-0.468632063 -1178,Q86C,0.056980234,0.005079041,-0.053058544,-0.060903586,-0.321765932,0.054265308,0.050612104,0.063348364,-0.050647145,-0.031272523,0.041430604,-0.124991973,0.018874886,-0.092022596,-0.029784576,-0.031664545,-0.611867318,1.264408989,2.364101861,-6.845409148,-7.045994118,-6.897099388,-6.254165146,-7.261225014,-6.768562073,-6.431794699,-3.368686122 -1179,Q86E,0.014009057,-0.02905182,-0.033168435,-0.027986848,-0.036396335,-0.03514691,-0.002393708,0.030411821,-0.045185489,-0.037197226,-0.020906413,-0.058880744,-0.007456126,-0.048213451,-0.007760245,-0.003490753,-0.069301916,1.25165709,2.497870252,-0.56897356,-0.564854874,-1.385282455,-0.215199806,-0.818287918,0.138757256,-2.548811528,0.799298091 -1180,Q86D,0.012097256,0.008241078,-0.016288709,0.028376834,0.009897319,-0.03610019,-0.011804887,0.035999398,0.065560531,0.066817638,-0.050335482,0.015636893,-0.04821431,0.03915387,0.017599798,0.127961722,-0.108167085,1.137663383,3.153120964,-2.872334956,-3.458039703,-2.707114525,-2.097564301,-3.836982376,-2.261973877,-2.20527596,-0.411848123 -1181,Q86G,0.026653939,-0.010489343,-0.031594417,0.01091036,-0.049850188,-0.004195942,0.014408697,0.038899181,-0.002439801,-0.003604824,-0.017373862,-0.019889041,-0.043299792,0.005985507,0.015835213,0.049427719,-0.149128095,1.078703398,2.790278556,-4.723375298,-5.032029518,-4.271832893,-4.18420089,-5.016516907,-5.11229628,-4.693500868,-0.25002365 -1182,Q86F,0.066157602,0.086695863,0.095739492,0.101461242,0.120341129,-0.048221266,0.106588026,0.025727178,0.245639815,0.244898795,-0.071507069,0.23490822,-0.043429237,0.195078133,0.00784435,0.287094218,-0.046411961,0.916551292,3.106668886,-7.558686885,-7.259739693,-7.606846161,-6.980115196,-8.072054085,-7.874679291,-6.490177642,-3.848821304 -1183,Q86I,0.010187368,0.012985412,-0.000515842,-0.006363107,-0.039301079,-0.090305139,0.008784131,0.011590605,0.0135243,0.026759105,-0.000788282,0.005157164,-0.006188848,-0.009526659,-0.003199554,0.003975811,-0.082577969,1.278431235,2.60751668,-4.15654048,-3.875455719,-3.467368057,-4.636154121,-4.323577507,-4.480146996,-3.869006896,-1.102176284 -1184,Q86H,-0.006931229,-0.018887575,0.007868559,0.041869927,-0.014527212,-0.019111457,-0.011217685,-0.002644772,0.017644317,0.011237216,-0.049012365,0.041166414,-0.025429297,0.043027766,0.040712087,0.060909713,-0.089964136,1.027434188,2.893681162,-3.952672131,-4.076336052,-4.169997749,-3.417893654,-3.811114319,-4.288018883,-4.042713633,-1.746444251 -1185,Q86K,0.023142166,-0.038368765,-0.019516181,-0.035926078,-0.009362488,-0.020474255,0.027832027,0.018452304,-0.017611261,-0.055638111,-0.021099419,-0.025556094,-0.013476267,-0.051049198,-0.020802958,0.036046664,-0.054771639,1.176585771,2.544189688,-1.062164688,-0.973031685,-0.557940353,-1.178966225,-1.218440567,-1.382444611,-2.244969801,0.920795435 -1186,Q86M,0.021486086,-0.053107154,-0.019208793,-0.039024577,-0.015556395,-0.018302093,0.0104392,0.032532972,-0.023963535,-0.062761779,-0.043452528,-0.02808196,-0.010335626,-0.076498374,-0.00155078,0.033250557,-0.064363346,1.182158972,2.665250158,-4.815128294,-4.813691818,-4.605895782,-5.0729049,-4.353488983,-5.229659988,-5.070485437,-1.991095524 -1187,Q86L,0.03601063,-0.065855974,-0.057251883,-0.053047971,-0.029438376,-0.048022767,-0.004101392,0.076122652,-0.119011618,-0.11632429,-0.015387657,-0.110540916,-0.003962849,-0.128861518,0.022765576,-0.041051158,-0.017825594,1.424189411,2.419766583,-2.887847513,-3.392307442,-2.124766884,-2.826176613,-2.831946152,-3.264040474,-3.028094817,-0.208691955 -1188,Q86N,0.052813944,0.014941384,0.047311009,0.031959916,0.014918119,0.010668411,0.055055438,0.050572449,0.065201932,0.051709553,-0.021826785,0.082065431,0.012556586,0.05551403,0.008405802,0.09688875,-0.067052512,1.671448915,3.643209181,-3.424274883,-2.729698265,-2.773420929,-4.442790962,-3.748093155,-3.427371101,-5.08503115,-0.732273627 -1189,Q86P,-0.009947522,-0.044456859,-0.027340155,-0.251576877,-1.368783659,0.014785847,-0.002880681,-0.017014362,0.008951367,-0.005580672,-0.083333046,-0.031291486,-0.023388824,0.053070648,-0.556224401,-0.944686425,-1.792880893,0.649451662,1.354221043,-5.822575835,-6.75347406,-4.318740707,-4.664931084,-5.837925644,-7.537807678,-4.91839368,-0.384292676 -1190,Q86S,0.034026422,0.001047659,0.012151944,0.00781268,0.01643971,-0.025380116,0.011065115,0.056987729,0.051857788,0.037775495,-0.035680178,0.023041511,0.001262377,0.021092223,-0.005466864,0.087244329,-0.054364909,1.07861636,2.828609385,-2.581544148,-2.332343132,-2.563018623,-2.588738853,-2.665047859,-2.758572273,-3.621761651,-0.856813655 -1191,Q86R,0.024864589,0.015786257,-0.006739471,0.015121835,0.007385751,-0.011459622,0.010708429,0.039020748,-0.003486922,0.012550391,0.019022122,-0.005969584,-0.007509357,0.024096744,0.006146925,0.054593341,-0.039821839,1.543610422,3.106887046,-2.639448869,-3.068323784,-2.20178212,-2.565021729,-2.905449806,-2.456666908,-3.379767771,0.608657632 -1192,Q86T,0.014450946,0.01220451,0.034871917,0.040506007,0.065980786,0.000805923,0.004099858,0.024802033,0.115368541,0.063387254,-0.038978235,0.088499541,-0.018755707,0.066634553,0.01437746,0.171481181,-0.03951961,0.983262629,3.008525655,-2.407377893,-1.951716888,-2.712924957,-2.196135353,-2.540507866,-2.635604401,-3.515539468,-0.211520167 -1193,Q86W,0.01317419,-0.016584198,0.005834941,0.024550323,-0.024832316,-0.02360262,-0.019715075,0.046063455,0.044256398,-0.002153,-0.031015395,0.032596661,-0.02092678,0.042155534,0.006945112,0.076477848,-0.12614248,1.223759613,2.920356167,-7.4031231,-7.381430695,-6.755933403,-7.144129486,-7.723874313,-8.010247604,-6.551369403,-3.486995392 -1194,Q86V,0.02515177,-0.005327217,-0.000314841,0.030028581,-0.002231503,-0.009557375,0.009316399,0.04098714,0.036916186,0.012136304,-0.022790738,0.013956689,-0.014586371,0.048423533,0.011633629,0.071809238,-0.076272243,1.025394224,2.831263812,-3.667203548,-3.859326523,-3.046392967,-3.701760948,-4.279509811,-3.449027489,-4.401748111,-1.215943085 -1195,Q86Y,0.01708332,0.064060429,0.047005165,0.075821362,0.037876743,0.000714221,-0.009313247,0.043479886,0.138033242,0.14033513,-0.012214273,0.095895309,-0.001884979,0.168180255,-0.016537531,0.187855542,-0.112102057,1.045878245,3.047933994,-7.934539604,-7.373708221,-8.520482262,-7.217358536,-8.229860832,-8.33128817,-6.559336351,-3.765829055 -1196,E87A,0.054883243,0.12666019,0.105446796,0.165353435,-1.004393455,0.091274437,0.043757523,0.066008962,-0.030057431,0.100095635,0.153224744,0.118890068,0.092003523,0.149254478,0.181452391,-1.019388988,-0.989397922,0.495040119,1.333229684,-5.109531859,-4.305268311,-5.23374456,-4.89247052,-4.810771545,-6.305404358,-4.816919586,-0.765680897 -1197,E87C,0.083543301,0.100352562,0.021368566,0.067982757,-1.900269091,0.028776696,0.076584461,0.09050214,0.042291373,0.005791918,0.194913205,-0.069719943,0.112457075,-0.005863935,0.141829449,-1.607051158,-2.193487023,1.035999276,1.342789724,-10.38377314,-8.949290771,-9.342740807,-12.27384235,-10.2269903,-11.12600146,-8.052197659,-4.577108993 -1198,E87D,0.004289735,0.064088914,0.079818068,0.094421639,-0.007214053,0.112590217,0.034187925,-0.025608456,0.037267668,0.029247439,0.098930389,0.03391231,0.125723826,0.049829205,0.139014073,-0.014168354,-0.000259751,1.100536909,2.511960346,-2.895462837,-2.146538925,-3.655558701,-2.437914207,-2.752583984,-3.484718369,-3.751197849,-1.225791238 -1199,E87G,0.007300494,0.060079602,0.060965484,-0.326062156,-1.669198546,0.059615249,0.025781863,-0.011180875,0.065344327,0.030266537,0.089892666,0.001194078,0.120736889,-0.174661995,-0.477462316,-1.845745525,-1.492651567,1.115474229,1.328659398,-6.990573077,-7.133951424,-6.714056786,-6.373129494,-6.809387787,-7.922339897,-4.821822611,-1.001575842 -1200,E87F,0.04914198,0.051986751,0.030353305,0.025354564,-0.292764895,-0.037387451,0.040665562,0.057618397,0.02263839,0.023670926,0.080302575,-0.000231223,0.060937832,0.03474228,0.015966847,-0.3001498,-0.28537999,1.171795417,1.80539168,-10.42113898,-8.35676181,-8.142894821,-13.76812366,-10.19023107,-11.64768356,-6.02970109,-0.818100575 -1201,E87I,0.09015658,0.029362755,0.058077969,0.088589461,-0.022245569,0.021994294,0.084436439,0.09587672,-0.005943343,-0.059381691,0.1181072,-0.012130446,0.128286383,0.008549631,0.16862929,-0.117805502,0.073314364,1.220664437,2.171555293,-7.880623145,-6.270932487,-6.537848251,-10.56727208,-6.855609108,-9.171453796,-4.237217909,-0.143900103 -1202,E87H,0.047969527,0.051791519,0.01778261,-0.61044485,-1.85153629,0.033351715,0.027467834,0.06847122,-0.039872791,-0.010254558,0.113837595,-0.079695121,0.11526034,-0.38122881,-0.839660889,-1.82429617,-1.878776409,1.598855377,1.402481421,-9.674004613,-8.425328293,-8.942672455,-11.23184199,-9.986610176,-9.783570152,-6.670784713,-3.444396428 -1203,E87K,0.013536526,0.096589505,-0.114560886,-1.587200639,-2.921329819,0.032324692,0.05148128,-0.024408229,-0.058274234,0.005664195,0.187514815,-0.102857567,-0.126264204,-1.529303485,-1.645097793,-2.355935728,-3.48672391,0.994977741,0.727246155,-7.393051468,-6.133995041,-6.561500107,-8.858368607,-7.263125954,-8.148267632,-6.562240975,-2.857111791 -1204,E87M,0.068093573,0.044894984,0.057469567,0.069565683,-0.031613816,-0.015411294,0.071053867,0.065133279,-0.0386477,0.012640753,0.077149214,-0.018105581,0.133044714,0.010450761,0.128680604,-0.107415018,0.044187387,1.391309677,2.273813163,-9.428950948,-7.223950737,-7.994802094,-12.29516174,-9.116459679,-10.51438049,-5.698153263,-2.433969709 -1205,E87L,0.081300597,0.022253731,0.051457393,0.057691701,0.024209124,0.00381098,0.057405341,0.105195853,0.02846004,-0.032977778,0.077485239,0.000333529,0.102581257,0.028271808,0.087111593,-0.044644188,0.093062435,1.249082587,2.535920033,-7.294717725,-5.144012169,-6.407903603,-10.31099616,-6.403014519,-8.20766217,-4.639645631,1.020998265 -1206,E87N,0.063549015,0.06770328,0.017724999,-0.217726669,-1.647481185,-0.009383554,0.057491,0.069607029,0.106891131,-0.019099434,0.154505994,-0.057378454,0.092828452,-0.169533403,-0.265919935,-1.605613572,-1.689348797,1.156391875,1.356477909,-8.230363306,-7.046586426,-8.141545563,-8.497781738,-8.546940002,-8.918962799,-6.09893344,-2.798043109 -1207,E87Q,0.089780716,0.073974223,0.069884161,0.09814517,-1.176308169,0.024947124,0.088517434,0.091043997,0.023194673,0.01691762,0.131030825,0.012606254,0.127162067,0.055443081,0.140847258,-0.945349995,-1.407266342,0.57939509,1.344701524,-5.660011464,-4.589993034,-5.380128426,-6.846401016,-5.089128922,-6.394405922,-4.997555305,-2.506625759 -1208,E87P,0.039084006,0.054488055,-0.956548451,-1.5627208,-2.483551041,0.021973349,0.03843972,0.039728292,0.070408948,0.008229906,0.100746203,-0.923837044,-0.989259857,-1.626690482,-1.498751118,-2.44108827,-2.526013811,2.629287743,1.399998579,-9.59027757,-8.677533363,-9.330235435,-9.814526756,-9.190364647,-10.93872765,-6.823961098,-3.43171913 -1209,E87S,0.06732751,0.067180298,0.060565692,0.027247136,-1.501669116,0.001751896,0.074472033,0.060182986,0.055011633,0.006869432,0.127491164,-0.015493933,0.136625316,0.012197678,0.042296593,-1.52140875,-1.481929481,0.825675763,1.328971383,-7.283317014,-6.682900093,-6.386404564,-7.136829201,-7.453746506,-8.756704704,-5.561082207,-1.748758662 -1210,E87R,0.052542878,0.07353947,-0.366531139,-1.502997067,-2.347803569,0.023305977,0.040682587,0.064403168,-0.014786342,0.006001723,0.141077217,-0.312222053,-0.420840225,-1.424023849,-1.581970285,-2.219398399,-2.476208739,2.537231438,1.557851047,-8.399886427,-7.912161057,-7.530149826,-10.02127084,-8.311711922,-8.224138489,-6.400540251,-2.438892904 -1211,E87T,0.059717829,0.039958259,0.074538331,0.046758354,-0.836128657,0.032342211,0.075538482,0.043897175,-0.010307767,-0.00384867,0.083765188,0.049661355,0.099415306,0.060975779,0.032540929,-0.738611421,-0.933645893,0.604118538,1.371670957,-7.627686154,-6.561831055,-7.017760857,-7.97037838,-7.857640007,-8.730820473,-6.157600948,-2.21548644 -1212,E87W,0.048311983,0.023110037,0.022301841,-0.019671466,-1.558419284,0.028381317,0.051630113,0.044993853,0.040047417,-0.053412885,0.099632958,-0.075100475,0.119704157,-0.030112413,-0.009230518,-1.668311959,-1.448526608,0.818431909,1.320720501,-10.22769793,-7.922635277,-9.544488258,-14.2716673,-10.16517268,-9.234526146,-6.800990403,-2.376910186 -1213,E87V,0.081343989,0.044799356,0.07124581,0.065744569,-0.121958186,0.006778424,0.093958637,0.068729341,-0.036123532,-0.014817104,0.104415815,-0.013312306,0.155803925,-0.011845022,0.14333416,-0.184674276,-0.059242095,1.410200423,2.140588757,-7.547631706,-6.13289547,-6.800055481,-10.09403954,-6.070106857,-8.64106118,-4.714836989,-0.965267733 -1214,E87Y,-0.005737367,0.048880076,0.024767855,0.050577964,-1.632880381,-0.017911589,-0.02364949,0.012174756,0.089945711,0.028020657,0.069739495,-0.012671848,0.062207558,0.092845106,0.008310821,-1.696894953,-1.568865808,0.571382956,1.305859542,-10.94317333,-9.091825294,-9.292912636,-14.0056796,-10.8393398,-11.48610933,-6.652347876,-2.60354004 -1215,Q88A,0.032303935,-0.015409259,-0.027838091,0.03415031,-0.0001203,-0.035432434,0.021772299,0.04283557,0.088429217,0.010011893,-0.040830411,-0.017427823,-0.038248359,0.059166552,0.009134068,0.014003903,-0.014244502,1.179757852,2.671965215,-3.386064307,-2.923111443,-3.868487556,-3.178307014,-3.608939285,-3.351476234,-4.225214262,0.020429424 -1216,Q88C,-0.040941677,-0.073486293,-0.073897993,-0.006473535,-0.273911584,0.100564635,-0.012769836,-0.069113517,0.17245165,-0.089201312,-0.057771274,-0.047888033,-0.099907952,-0.004574954,-0.008372115,-0.174510014,-0.373313154,1.51144349,2.303796746,-8.662211247,-7.426382942,-8.959202347,-9.119914383,-8.223079483,-9.582477081,-7.824141543,-3.374428472 -1217,Q88E,0.033023935,0.029500985,0.025920347,0.068388539,0.029576106,0.012693642,0.045343303,0.020704567,0.008080748,0.084087575,-0.025085606,0.051842054,-0.00000136,0.083649352,0.053127725,0.095611985,-0.036459774,1.171185794,2.904147458,-3.439844473,-3.087555466,-4.034687431,-3.5421092,-3.465282173,-3.069588097,-5.064371867,-0.234176939 -1218,Q88D,0.022855594,0.02456005,-0.005967556,0.043833308,0.077216808,0.004687223,0.035174185,0.010537002,-0.033243538,0.088733325,-0.039613225,0.062220465,-0.074155576,0.07866574,0.009000876,0.082354001,0.072079615,1.127534701,2.963893093,-3.121262482,-3.197294182,-2.835037033,-3.698879784,-3.296120384,-2.578981026,-3.007647053,1.493232928 -1219,Q88G,0.04705773,-0.009602994,0.00781269,0.049287055,-0.081860912,0.030387405,0.052403639,0.041711821,0.055818228,0.010954182,-0.030160169,0.002488386,0.013136994,0.067006761,0.031567348,-0.07757111,-0.086150713,1.36154686,2.439371247,-6.182214548,-6.135061653,-5.507951859,-6.11832206,-6.757287346,-6.392449821,-5.107864775,-0.526146201 -1220,Q88F,-0.051611405,-0.001272796,-0.026454515,0.035217414,-0.058579433,0.014499252,-0.047894106,-0.055328704,0.019886128,0.043048404,-0.045593996,-0.057967322,0.005058293,0.072369524,-0.001934696,-0.028456465,-0.0887024,1.260158852,2.625263493,-9.651248251,-9.075219673,-10.56626432,-10.03139586,-9.146704521,-9.436656883,-5.807136816,-0.618946565 -1221,Q88I,-0.047526307,-0.083006531,-0.033625046,-0.022435838,-0.077210232,-0.019313336,-0.052195751,-0.042856863,-0.00281786,-0.08216966,-0.083843402,0.025494395,-0.092744487,0.0710031,-0.115874775,-0.012328306,-0.142092157,1.347832118,2.815643762,-7.753530051,-8.301544456,-8.267427223,-8.439984612,-6.282780869,-7.475913094,-6.210047906,-2.479619024 -1222,Q88H,-0.024172063,-0.038350228,-0.034833698,0.027203093,0.015802767,-0.013159448,-0.00938302,-0.038961106,0.035369685,-0.007643111,-0.069057345,-0.021554512,-0.048112883,0.065103292,-0.010697106,0.020949181,0.010656352,1.129499537,2.631264114,-5.045301859,-3.670024429,-6.329617554,-5.682545189,-4.664576599,-4.879745522,-5.725762321,-0.735535917 -1223,Q88K,0.046121101,0.00634495,0.00645875,0.074857676,0.094749771,-0.010936445,0.063996574,0.028245627,-0.056047229,0.075032865,-0.062342966,0.032622348,-0.019704848,0.080969695,0.068745657,0.097505345,0.091994196,1.077968091,3.00832055,-2.625496646,-1.997339401,-2.664619804,-2.710523666,-3.92558934,-1.829411018,-4.323068997,0.35741959 -1224,Q88M,0.075918719,-0.023065219,0.023385101,0.054149654,-0.014628486,0.077437063,0.079774818,0.072062619,-0.000933716,0.003549997,-0.049680435,0.005469444,0.041300758,0.052563395,0.055735912,-0.016224552,-0.01303242,1.164682365,2.593359679,-7.143543129,-7.852766991,-7.307869286,-7.825549171,-5.65929599,-7.072234207,-6.556273478,-3.074228615 -1225,Q88L,0.007272375,-0.01590591,-0.014248538,0.053277424,-0.004543879,0.019477542,0.026567536,-0.012022786,0.060152979,0.009905035,-0.041716855,-0.000658291,-0.027838784,0.054556895,0.051997952,0.003643588,-0.012731346,1.181087765,2.734850613,-6.93084707,-8.129996185,-7.371398834,-6.923690071,-4.601644165,-7.627506096,-5.094279447,0.177777375 -1226,Q88N,0.023390104,0.062870117,0.018556473,0.053838136,0.027462082,0.015104343,0.021971547,0.02480866,0.117715198,0.081119066,0.044621168,0.015099266,0.02201368,0.090515013,0.017161259,0.001616001,0.053308162,1.215283235,2.626997034,-3.558646234,-2.89177607,-3.395999046,-4.811606354,-3.835857224,-2.857992477,-4.418844909,0.038828496 -1227,Q88P,0.004069339,-0.002046575,-0.003931544,-1.051082846,-1.926862363,0.04538372,0.033691344,-0.025552667,0.016553503,0.024020714,-0.028113864,-0.014349491,0.006486404,-0.753705432,-1.348460259,-1.832166218,-2.021558507,2.070845646,1.55745784,-7.481086397,-7.668603554,-8.271829117,-6.771355301,-6.536837883,-8.156806129,-5.659667868,-0.88914366 -1228,Q88S,0.04584819,0.017622921,0.001565274,0.052350891,0.023680339,-0.021339894,0.061349062,0.030347317,-0.001454297,0.0217976,0.013448241,-0.004035483,0.007166031,0.059910211,0.04479157,0.037539151,0.009821527,1.037378169,2.727818375,-1.831365651,-1.016592896,-1.615217934,-1.906691536,-2.351303444,-2.267022446,-4.137699422,1.343793049 -1229,Q88R,-0.01289243,0.005446904,0.007890047,0.03952838,0.016367382,0.003979693,0.024294977,-0.050079836,0.039696112,0.042148257,-0.031254449,0.047994661,-0.032214567,0.068027447,0.011029313,0.050896934,-0.01816217,1.199379632,2.858891578,-2.482859642,-2.144382294,-2.314331551,-3.081089745,-2.605703911,-2.26879071,-4.12925958,0.685969675 -1230,Q88T,0.054437564,0.003298217,-0.005184351,0.059950844,0.023069694,-0.005686804,0.06190093,0.046974197,0.068469876,0.021302753,-0.01470632,-0.014790447,0.004421745,0.070074622,0.049827065,0.023458215,0.022681172,1.188531919,2.805887005,-3.458437718,-3.115571442,-3.218177414,-3.536492599,-3.521244431,-3.900702705,-4.353934943,0.061247845 -1231,Q88W,-0.412840743,0.0236892,0.031385505,0.09347412,0.052154614,0.003122381,0.044635009,-0.870316495,0.041508533,0.035905463,0.011472936,0.030721397,0.032049612,0.073282867,0.113665373,0.050221334,0.054087893,1.088249664,2.862947136,-8.837188876,-8.985157631,-8.643806488,-9.485841499,-8.663544563,-8.4075942,-7.052918604,-3.615310684 -1232,Q88V,-0.002694602,-0.011098924,-0.018490376,0.039814456,-0.02038913,0.048306112,0.007917262,-0.013306466,0.127186679,0.043602325,-0.065800172,0.009339336,-0.046320088,0.046639625,0.032989286,0.021582492,-0.062360751,1.178292594,2.721646774,-6.605669193,-7.32097242,-7.009054916,-6.48372123,-5.790046783,-6.424550613,-5.400797804,-1.205014349 -1233,Q88Y,0.062750868,0.036273293,0.059185774,0.096223861,0.087859613,-0.040043254,0.055352346,0.070149389,0.000498419,-0.00957765,0.082124235,0.050635757,0.067735791,0.034095971,0.15835175,0.045104045,0.13061518,1.103531468,2.759759629,-10.04468634,-8.867099701,-12.81490498,-10.72910564,-9.906172935,-7.90614843,-6.164251658,-1.175744443 -1234,L89A,-0.0331373,0.026295917,0.005897541,0.023746114,-1.51750046,0.029461063,-0.050264891,-0.016009708,0.058154965,0.012168565,0.040423269,-0.017321406,0.029116487,0.036463649,0.011028579,-1.395263142,-1.639737777,0.524565597,1.316404986,-6.850393228,-8.54612838,-5.599433121,-6.266668236,-4.268734589,-9.571001816,-5.757854804,-3.838718528 -1235,L89C,-0.032035051,-0.047588781,0.000156431,-0.738707383,-2.106335815,0.06663966,0.030760566,-0.094830667,-0.01316245,-0.010253018,-0.084924543,-0.047435914,0.047748776,-0.357219189,-1.120195576,-1.846342595,-2.366329035,1.448092214,1.36903937,-9.333760999,-9.996754623,-8.107065094,-10.29357748,-7.340972725,-10.93043507,-8.574270393,-7.205445922 -1236,L89E,-0.144240677,-0.005066387,-0.033061639,-0.119348079,-2.122418487,0.067513892,-0.130356297,-0.158125057,0.016589631,-0.035970461,0.025837688,-0.056430701,-0.009692576,-0.037483386,-0.201212772,-1.590093049,-2.654743924,0.606928577,1.312592777,-8.444922304,-9.161046158,-7.516256905,-9.309865532,-5.278616608,-10.95882632,-7.087193859,-4.707221621 -1237,L89D,-0.028070645,-0.011812418,-0.03718106,-0.567271936,-2.198119647,0.02975867,0.036569785,-0.092711075,-0.104575553,-0.023877187,0.000252352,-0.110358512,0.035996393,-0.240018643,-0.894525228,-1.790693807,-2.605545486,1.337945635,1.361248888,-10.59852311,-11.13122562,-10.50541126,-11.12417969,-7.219189926,-13.01260904,-8.703510343,-6.994136912 -1238,L89G,-0.084101868,-0.066134403,-0.017140445,-0.092382813,-1.746458061,0.081697024,-0.058392574,-0.109811161,-0.064874377,-0.069999869,-0.062268936,-0.037232239,0.00295135,-0.023834576,-0.160931049,-1.649143358,-1.843772763,0.809782761,1.320241194,-8.905263551,-11.1658943,-6.790520821,-7.243362785,-6.352322327,-12.97421752,-6.909456621,-3.674713745 -1239,L89F,-0.071190157,-0.018021565,-0.054275304,-0.013491772,-1.065589855,0.092708,-0.038948621,-0.103431692,0.063829767,0.014628826,-0.050671955,-0.050521842,-0.058028765,0.012093332,-0.039076876,-0.69421588,-1.436963829,0.977434223,1.48118201,-5.65416026,-4.495923042,-5.155984276,-7.491745323,-4.225370766,-6.901777893,-5.755822634,-3.207502007 -1240,L89I,-0.057288926,0.017897855,-0.000609927,0.019027822,-0.292830677,0.07447266,-0.052333629,-0.062244222,0.002992342,0.043046144,-0.007250434,0.003479199,-0.004699053,0.045128678,-0.007073034,-0.222177393,-0.36348396,1.129624275,1.903709181,-4.963014446,-3.959351097,-5.042844704,-6.540368103,-4.299750763,-4.972757561,-6.687052916,-4.071985403 -1241,L89H,-0.066808811,0.037923033,-0.002138622,-0.099198802,-1.515653905,0.05619785,-0.032363972,-0.10125365,-0.027921802,0.008170796,0.067675269,-0.028204555,0.023927312,-0.042124708,-0.156272896,-1.326619888,-1.704687921,0.62105932,1.325201835,-11.13889943,-11.87304268,-9.646602234,-13.14196828,-7.74784182,-13.28504211,-8.79962263,-7.838990008 -1242,L89K,-0.09268154,-0.042553043,-0.057566618,-0.942924429,-1.904393277,0.013784418,-0.06931723,-0.116045849,-0.001186848,-0.038075299,-0.047030786,-0.089104388,-0.026028847,-0.678221832,-1.207627026,-2.045966312,-1.762820241,1.901376091,1.429161537,-7.882206352,-8.039312859,-6.838080307,-9.410864403,-4.972162872,-10.15061132,-6.648005591,-4.702790255 -1243,L89M,-0.000443625,0.045658412,0.022507745,0.026469618,-0.068121536,-0.009742648,-0.004588857,0.003701607,-0.01472993,0.06358678,0.027730043,0.024989584,0.020025906,0.054557014,-0.001617778,-0.036660103,-0.099582968,1.186638969,2.423267269,-4.330127113,-4.464801758,-4.513537842,-4.063312607,-3.514838379,-5.094144981,-4.764745769,-3.049941769 -1244,L89N,-0.107009849,-0.054181648,-0.035920652,-0.88043269,-1.80739076,0.045476998,-0.097235688,-0.11678401,-0.044719852,-0.052161928,-0.056201368,-0.04384728,-0.027994023,-0.486449687,-1.274415692,-1.823764211,-1.791017309,1.736100391,1.44378924,-10.90591121,-11.57756381,-9.295157425,-12.74595065,-8.201983734,-12.70890043,-9.998314174,-10.17081188 -1245,L89Q,-0.107186166,0.005015638,-0.052263443,-0.194378665,-1.814728086,0.016471031,-0.097317982,-0.11705435,-0.07618405,0.012991655,-0.00296038,-0.080622997,-0.023903888,-0.057496415,-0.331260915,-1.518780292,-2.11067588,0.792977121,1.325654072,-9.383496912,-10.36147267,-8.377760925,-10.01275784,-6.680069939,-11.48542318,-7.881913441,-6.789696322 -1246,L89P,-0.098971778,0.013461446,-0.01431799,-0.018416175,-1.452205367,0.081698752,-0.0587332,-0.139210355,-0.019419862,0.044820926,-0.017898034,0.024876274,-0.053512254,0.029419508,-0.066251857,-1.18920866,-1.715202073,0.600028982,1.332342102,-4.349791417,-5.824621719,-3.766702133,-4.10814518,-3.233888092,-4.81559996,-4.568451422,-2.410204968 -1247,L89S,-0.062074941,0.012466754,0.014875631,-0.039904976,-1.679578282,0.036591066,-0.053425239,-0.070724643,0.008494536,0.0171231,0.007810408,-0.003398579,0.033149841,0.017010312,-0.096820263,-1.565549464,-1.7936071,0.444772139,1.305615736,-7.523215785,-8.811308662,-5.523319252,-8.365351532,-5.4061026,-9.50999688,-6.389438281,-5.690885673 -1248,L89R,-0.096017579,-0.018799198,-0.041750739,-1.382442513,-2.009935743,0.093546106,-0.056395342,-0.135639816,-0.024210455,0.001923363,-0.039521759,-0.043965622,-0.039535855,-1.090106123,-1.674778902,-1.672840867,-2.347030618,3.092633872,2.351608227,-8.243879688,-8.656393852,-7.563850655,-8.754122261,-5.239022522,-11.00600915,-6.83988968,-4.232003412 -1249,L89T,-0.075303194,0.050997239,-0.022623017,-0.063514654,-1.712095064,0.037857075,-0.047637797,-0.10296859,0.017302295,0.065131414,0.036863063,-0.007854076,-0.037391957,0.020170445,-0.147199753,-1.544284074,-1.879906053,0.63772385,1.31531363,-7.492383464,-8.266606987,-6.207190674,-7.900169579,-5.343486794,-9.744463287,-7.020355919,-5.658127192 -1250,L89W,-0.011960913,0.016185593,0.050832994,0.010374732,-1.733268579,0.076079398,0.011712726,-0.035634552,-0.024200128,-0.009695461,0.042066646,0.035453659,0.066212329,0.032927923,-0.012178459,-1.453506344,-2.013030813,0.669867962,1.321818429,-8.652681238,-8.597268486,-9.088394775,-9.872710548,-5.025510574,-10.6795218,-6.235483872,-3.727466158 -1251,L89V,-0.067685159,-0.013697971,-0.008251293,0.017593182,-1.52692744,0.051349592,-0.043935337,-0.09143498,-0.075787687,0.004725166,-0.032121107,0.010179982,-0.026682568,0.092129855,-0.056943492,-1.379774688,-1.674080191,0.458850662,1.313222772,-6.540043878,-6.485164795,-6.424135033,-7.324992073,-5.267949127,-7.197978363,-6.179949211,-4.783772744 -1252,L89Y,-0.075254154,0.003658612,-0.005657211,0.016827778,-1.435450717,0.113488515,-0.054164685,-0.096343623,-0.019203338,0.048914348,-0.041597124,-0.016534552,0.00522013,0.048502109,-0.014846553,-1.425360386,-1.445541047,0.534130177,1.315096776,-9.192504749,-8.570032768,-8.857753357,-11.22088213,-6.385316536,-10.92853895,-6.781709924,-3.6356643 -1253,G90A,-0.013649133,0.031624062,-0.042089287,0.013255169,-0.011699145,0.067484269,0.027236271,-0.054534537,-0.052504123,0.05743088,0.005817243,-0.010191369,-0.073987204,0.065193979,-0.038683642,-0.008293503,-0.015104786,1.169637137,2.558734278,0.347780147,0.502114807,-0.11991011,0.540211647,0.475235489,0.341248901,-0.867778738,1.050190804 -1254,G90C,0.073141673,0.006536331,0.01349705,0.002004083,-0.975286612,0.107913466,0.056582713,0.089700633,-0.100014197,-0.036596392,0.049669054,-0.063248099,0.090242198,-0.048390006,0.052398171,-0.87078115,-1.079792074,1.014542926,1.436812988,-4.375274692,-3.990473106,-3.985583504,-4.978669464,-4.195190437,-4.726456947,-6.109690809,-3.895430461 -1255,G90E,0.02561343,-0.015886724,-0.018965453,0.013572236,0.041201227,0.012981401,0.038608126,0.012618733,-0.052711037,0.005447952,-0.0372214,0.016528821,-0.054459726,0.033237976,-0.006093504,0.051468814,0.03093364,1.110969013,2.691206778,1.578199817,1.546856384,1.606468582,0.981505455,2.301201408,1.454967255,-0.397489403,1.229441899 -1256,G90D,-0.060325971,-0.065042279,-0.057216786,-0.032171239,-0.005478862,0.011807307,-0.023678331,-0.09697361,-0.145721249,-0.014955032,-0.115129526,-0.039052177,-0.075381395,0.049052557,-0.113395035,-0.002555197,-0.008402527,1.374463217,2.813746024,2.33596237,2.31446077,1.732279861,1.728860184,3.514579483,2.389631554,1.167093816,2.619707164 -1257,G90F,0.042628124,-0.024018391,-0.078979982,0.037264197,-0.131499981,0.010466486,0.065979325,0.019276922,-0.12481385,0.040068135,-0.088104916,-0.04900766,-0.108952304,0.0683284,0.006199994,-0.070744268,-0.192255694,1.260296383,2.376456284,-4.29258084,-3.552814285,-3.769783119,-5.788547501,-3.918591888,-4.433167404,-5.321456885,-3.105097895 -1258,G90I,0.002888562,-0.064936436,-0.026845417,0.013477233,-0.135224833,0.021733745,0.039848469,-0.034071346,0.013850265,-0.037380698,-0.092492173,-0.002474619,-0.051216214,0.011964383,0.014990082,-0.097576952,-0.172872713,1.307517609,2.287544969,-4.439312163,-3.445296371,-4.549177803,-5.130625496,-4.27754081,-4.793920334,-5.442943899,-3.593982372 -1259,G90H,-0.035120018,-0.00225988,-0.046302202,-0.022072485,-0.0363664,0.015426306,0.001165859,-0.071405895,-0.054758921,0.087495374,-0.092015133,-0.001142491,-0.091461912,0.088025388,-0.132170357,0.022700627,-0.095433426,1.161577178,2.80785781,-2.214704089,-2.184244568,-2.184709663,-2.993367813,-1.343070923,-2.36812748,-3.701098063,-0.526488823 -1260,G90K,-0.047787408,-0.044188693,-0.075036389,-0.026130331,-0.108828669,0.030080282,-0.033801923,-0.061772893,0.027623552,0.003706253,-0.092083638,-0.023993835,-0.126078942,0.029014982,-0.081275644,-0.064238083,-0.153419254,1.308724841,2.444385149,-1.029455095,-0.665827843,-1.022767685,-2.153696175,0.290692223,-1.595675995,-3.561408416,-0.524244867 -1261,G90M,-0.077176066,0.020540893,-0.061032885,-0.03129388,-0.039755865,0.057239852,-0.059311494,-0.095040637,-0.054770488,0.075723731,-0.034641946,-0.050641593,-0.071424176,0.029923518,-0.092511277,-0.028009742,-0.051501988,1.153119917,2.483269178,-3.380902838,-3.096074379,-3.224320137,-4.339163193,-3.048957199,-3.195999283,-4.690708083,-2.197064398 -1262,G90L,-0.022481755,-0.036988303,-0.045980277,-0.042022018,-0.128355617,-0.002636621,-0.019120554,-0.025842955,-0.02504406,0.017058429,-0.091035034,-0.027581368,-0.064379186,-0.008597776,-0.07544626,-0.08607041,-0.170640824,1.317843664,2.272856615,-3.657806601,-3.357116364,-3.359164497,-4.359600189,-3.39148851,-3.821663445,-5.127039124,-1.840108407 -1263,G90N,0.006343597,0.030640358,-0.032043377,-0.057378282,0.017350079,0.031535966,0.06217728,-0.049490086,-0.022617247,0.083460573,-0.022179857,-0.019254799,-0.044831955,-0.079621244,-0.035135319,0.024723835,0.009976322,1.246537915,2.6730107,0.461524382,0.903820244,0.194623665,-0.936723015,2.509061478,-0.363160461,-1.174435143,1.098494901 -1264,G90Q,0.017906928,-0.012561158,-0.024980777,0.001080846,0.072975398,-0.027823413,0.030618935,0.00519492,-0.006817212,0.005573798,-0.030696114,0.008434617,-0.058396171,0.015396912,-0.01323522,0.03720463,0.108746166,1.144309066,2.690097492,-0.225791658,-0.060725449,-0.541879868,-0.766580666,0.317155289,-0.076927597,-2.908969251,0.38408995 -1265,G90P,-0.013313484,-0.012883043,-0.053745142,-0.027673671,-0.68542057,0.069054024,0.012811323,-0.039438291,-0.018589675,0.048545831,-0.074311916,-0.051992995,-0.055497288,0.016172166,-0.071519508,-0.482410657,-0.888430483,1.037036757,1.574487789,-3.999522859,-3.957960838,-4.067958153,-4.165689438,-3.940905617,-3.86510025,-4.870941022,-2.924892253 -1266,G90S,-0.024565004,-0.007594556,-0.037740391,-0.036856002,-0.020904624,0.008073971,-0.01278993,-0.036340078,-0.025510036,0.011574067,-0.026763179,-0.013209936,-0.062270846,0.010040401,-0.083752405,-0.028674188,-0.013135059,1.205897036,2.468424679,1.199482962,1.618060768,1.671185806,0.663164131,1.086216354,0.95878775,-1.733391537,1.014104043 -1267,G90R,-0.011144793,-0.029979371,-0.027049356,-0.028472153,-0.145842567,0.066396362,0.013568599,-0.035858185,-0.047361484,0.00678143,-0.066740172,0.017705916,-0.071804628,0.016812739,-0.073757045,-0.093500585,-0.198184549,1.416106414,2.383663826,-2.351770699,-2.787357956,-2.659085403,-2.551516113,-2.200635124,-1.560258896,-3.955069528,-0.129797563 -1268,G90T,-0.01367986,-0.009774634,-0.05549761,-0.014621774,-0.032386576,0.027424319,0.015698497,-0.043058217,-0.0800005,0.007263376,-0.026812644,-0.058674599,-0.05232062,0.02438371,-0.053627258,-0.002251031,-0.06252212,1.19982473,2.625129314,0.332218887,1.087582489,0.689742142,-0.229153137,-0.063707809,0.176630753,-1.713839199,0.908261881 -1269,G90W,0.031069977,-0.064791756,-0.115450201,-0.076960094,-0.044056476,-0.024997495,0.061015906,0.001124048,-0.072133017,-0.058971317,-0.070612194,-0.11281117,-0.118089232,-0.00405294,-0.149867248,-0.032777291,-0.05533566,1.155281826,2.460090148,-5.044825684,-4.739189026,-4.707842316,-6.01606926,-4.563046707,-5.19798111,-5.574649302,-3.987336781 -1270,G90V,-0.037485835,-0.00797489,-0.032687119,-0.022575779,-0.155368692,0.063601296,-0.033852512,-0.041119158,-0.020487712,0.03462074,-0.05057052,-0.051840006,-0.013534231,-0.012513136,-0.032638421,-0.093473901,-0.217263483,1.376014197,2.397550292,-4.381040456,-3.692340454,-4.47302375,-4.822299583,-4.329286354,-4.588252136,-5.905766611,-3.691706707 -1271,G90Y,0.045050518,-0.006018652,-0.047921822,-0.026719792,-0.065199464,-0.037243736,0.039923636,0.050177399,-0.039058585,0.042216339,-0.054253643,-0.061164007,-0.034679637,-0.029768751,-0.023670832,-0.091118209,-0.039280718,1.364757095,2.331489033,-3.110277296,-2.272916641,-2.363801697,-4.371236641,-2.830959908,-3.712471596,-3.802099989,-1.97873753 -1272,R91A,-0.00967035,0.055785266,0.006254716,0.017544559,-1.352936045,0.016006488,-0.019793734,0.000453035,-0.023253102,0.076339739,0.035230793,0.027031401,-0.01452197,0.060408821,-0.025319703,-1.07582265,-1.630049439,0.644716279,1.342459752,-5.840380174,-4.655249939,-7.064129158,-6.452024155,-5.65620504,-5.37429258,-4.361985447,-1.406258642 -1273,R91C,-0.028013412,0.029660241,-0.163516514,-1.296169983,-1.363640025,0.058398075,0.002028667,-0.05805549,0.074262809,0.051148858,0.008171623,0.055925055,-0.382958083,-1.069816496,-1.52252347,-1.69776873,-1.02951132,2.772857954,2.077546304,-10.27884372,-9.07363279,-11.05307439,-11.00135783,-9.738714119,-10.52743948,-7.732867523,-5.430577301 -1274,R91E,-0.023438773,0.064751486,0.059554225,-0.017830672,-1.843124163,-0.006955819,0.004490597,-0.051368143,-0.039733244,0.076561144,0.052941828,0.053459409,0.065649041,0.052639222,-0.088300565,-1.528472829,-2.157775497,0.664844662,1.317157412,-5.615023412,-4.520169151,-5.895663811,-6.016223198,-4.86084845,-6.782212448,-4.350516489,0.055298162 -1275,R91D,-0.090113133,0.054419126,0.028988269,-0.135003069,-1.653138449,0.012118761,-0.069764831,-0.110461434,0.032807231,-0.010537709,0.11937596,0.018791045,0.039185493,-0.021384848,-0.248621289,-1.434527295,-1.871749602,0.753720389,1.328321211,-4.667224915,-3.033386932,-5.960324432,-5.854367928,-3.541084572,-4.946960709,-3.334611166,-0.215152109 -1276,R91G,-0.036362733,0.02729582,-0.004293671,-0.843676104,-1.839828642,-0.014140812,-0.007793084,-0.064932381,0.01458025,0.024852125,0.029739514,-0.021342929,0.012755587,-0.532069061,-1.155283146,-1.757597681,-1.922059603,1.800958838,1.478660284,-8.603991109,-7.648721573,-9.472006805,-9.429393639,-7.880559578,-8.589273949,-6.567185891,-3.550973145 -1277,R91F,-0.033950647,0.066268207,-0.029661079,-0.154379854,-2.190379396,-0.049434724,-0.042734833,-0.02516646,0.086840222,0.053007136,0.079529278,-0.065033942,0.005711785,-0.105320679,-0.203439029,-1.972646007,-2.408112784,1.003704556,1.30917829,-11.84216129,-9.664563507,-11.35103831,-12.7735145,-11.75563979,-13.66605032,-8.19478142,-5.921714764 -1278,R91I,-0.056227788,0.003949605,0.003976111,-1.342748218,-1.776368346,0.037391957,-0.063466133,-0.048989443,0.001374013,-0.015288745,0.023187955,-0.032830678,0.0407829,-1.058869316,-1.626627119,-1.711645133,-1.841091558,3.43709409,2.683243196,-10.01708651,-9.062224045,-11.20580643,-10.34726086,-9.367227837,-10.10291337,-7.553228699,-5.36454876 -1279,R91H,-0.002327235,0.050562125,0.008185056,-0.041614867,-0.089973269,-0.000980151,-0.03265535,0.028000881,0.017979765,0.013219635,0.087904614,-0.045293474,0.061663586,-0.039542033,-0.0436877,-0.123303385,-0.056643153,1.326909262,2.244538031,-5.355508748,-5.162794487,-5.642671669,-5.948014999,-5.081060905,-4.943001678,-5.190025439,-2.646899052 -1280,R91K,-0.016886984,0.030871009,0.044181244,-0.008050242,-0.124753162,0.002753525,-0.026741721,-0.007032247,0.011060307,0.042053353,0.019688665,0.044154836,0.044207651,0.00312702,-0.019227503,-0.060279,-0.189227324,1.543610422,3.106887046,-4.997492682,-3.966701485,-5.242035698,-5.305514763,-4.398279778,-6.074931686,-4.077314994,-0.961435268 -1281,R91M,0.016601234,0.004205371,-0.001891278,0.048651268,-1.473200085,-0.001097249,0.02318271,0.010019757,-0.048839022,-0.014966017,0.023376759,-0.053902752,0.050120196,0.050901743,0.046400793,-1.50294877,-1.443451399,0.660407842,1.318602961,-8.425528963,-7.51768515,-8.804548561,-8.749572639,-8.160226219,-8.895612244,-5.903176602,-3.663119131 -1282,R91L,-0.040372273,0.034529846,-0.018983322,-0.356925079,-1.701135439,0.033695024,-0.000366401,-0.080378145,-0.025442076,0.008720858,0.060338834,-0.022526504,-0.01544014,-0.155890262,-0.557959896,-1.643634827,-1.75863605,1.108718043,1.349132705,-8.544838103,-8.215568665,-7.862359428,-9.440935249,-7.895217545,-9.310109627,-6.344775847,-4.051053959 -1283,R91N,0.024183516,0.065282619,0.003236394,0.043835618,-0.512989782,-0.010320457,0.004281332,0.044085699,-0.027981381,0.015579981,0.114985257,0.004986907,0.00148588,0.054458365,0.03321287,-0.391349627,-0.634629936,0.959204707,1.594013465,-6.664937654,-5.698930054,-8.23853019,-6.923328285,-5.965567711,-6.498332031,-4.759600775,-3.439779182 -1284,R91Q,0.003279587,0.076524345,0.018904481,0.060764536,-1.366879237,0.045696594,0.041986792,-0.035427619,0.039561558,0.081928661,0.071120028,0.046292977,-0.008484015,0.075508883,0.046020189,-1.177311635,-1.556446839,0.662049847,1.337049899,-4.460664192,-3.805291916,-4.983805611,-4.035660782,-4.186394241,-5.292168411,-3.813614832,-0.02630033 -1285,R91P,-0.019689701,-0.351512703,-1.684834607,-2.050477453,-2.571355016,-0.061552024,-0.012371757,-0.027007644,0.012672394,-0.243213413,-0.459811993,-1.595579318,-1.774089896,-2.07113481,-2.029820096,-2.396087455,-2.746622577,1.215644032,0.075611982,-11.09000541,-9.916807327,-12.15708882,-11.97887112,-10.427356,-10.96990378,-9.409700667,-8.783288814 -1286,R91S,-0.05486617,0.034438365,-0.01879807,0.006838716,-1.352494718,0.059137029,-0.044184738,-0.065547601,-0.02003438,0.003832443,0.065044287,-0.012678143,-0.024917996,0.024023182,-0.01034575,-1.372534984,-1.332454451,0.466966429,1.312525447,-5.930485863,-5.694097954,-6.636045403,-7.008242111,-5.538773262,-4.775270584,-4.933649994,-1.671240351 -1287,R91T,0.006034024,0.016851294,-0.0012853,0.011774613,-0.598956526,0.000731268,-0.010634444,0.022702492,-0.00866148,0.040466963,-0.006764376,0.00969554,-0.012266139,0.029292285,-0.00574306,-0.479136188,-0.718776864,0.388446809,1.377261345,-5.215698592,-4.495002243,-5.708961456,-5.846373665,-5.148950684,-4.87920491,-4.407822191,-0.866541636 -1288,R91W,-0.050481586,0.069254133,-0.003473855,-1.250980008,-2.215240255,0.008275399,-0.018429021,-0.08253415,-0.041056144,0.146873801,-0.008365536,0.022894148,-0.029841857,-0.837313119,-1.664646897,-1.727731953,-2.702748557,2.332359363,1.762587074,-10.62294972,-9.998049957,-11.03666017,-11.18492781,-10.45752449,-10.43758615,-8.710030576,-7.207296213 -1289,R91V,-0.018346995,0.027888465,-0.012152522,-0.513022669,-1.920734529,0.07378203,0.009377407,-0.046071396,-0.078731592,-0.019696836,0.075473766,-0.053851834,0.029546791,-0.294613795,-0.731431543,-1.866273866,-1.975195192,1.422809036,1.362824807,-9.823598924,-8.5694944,-11.25666138,-10.21012211,-9.235946739,-9.845769997,-7.585390583,-5.256167918 -1290,R91Y,-0.070865199,0.106844398,-0.007740066,-0.019365664,-2.267574631,0.038788245,0.016376676,-0.158107074,0.065765512,0.07733138,0.136357416,0.025427924,-0.040908056,0.000534427,-0.039265754,-1.786134969,-2.749014292,0.737933925,1.308669763,-11.51182513,-10.5559964,-12.44442852,-11.79199636,-11.22773044,-11.53897393,-7.997435473,-5.981887541 -1291,R92A,0.026271628,0.019577266,0.009473914,-0.053823062,-0.617133217,-0.019135413,0.002922575,0.049620681,-0.054635716,-0.025488953,0.064643485,0.005147109,0.013800718,-0.064472997,-0.043173126,-0.434919922,-0.799346512,1.34391434,1.786821188,-3.984273944,-3.516363075,-4.365804031,-4.978966225,-4.130205353,-2.930031036,-4.83048032,-2.192383569 -1292,R92C,0.018251484,0.06336801,0.074500534,-0.067920639,-1.457742572,-0.024893836,-0.003657996,0.040160963,-0.049334907,0.045328405,0.081407614,0.081098887,0.067902181,0.028657282,-0.164498559,-1.327608473,-1.587876671,0.640356936,1.326456918,-7.368115352,-6.548204544,-8.479263367,-7.795987244,-8.108190628,-5.908930977,-7.561589766,-4.956647049 -1293,R92E,-0.039345628,0.00232509,-0.008034667,-0.016457714,-0.591414856,-0.005663763,-0.034427252,-0.044264003,-0.088363019,0.010561055,-0.005910876,0.047788597,-0.06385793,-0.016425509,-0.016489919,-0.308839911,-0.873989801,1.624941907,2.169335106,-5.250857617,-5.028100693,-6.579368011,-5.674376732,-6.183623299,-2.788819351,-4.740956027,-1.552171489 -1294,R92D,0.00152879,0.051200138,0.05550978,-0.061650037,-1.554089535,-0.039839619,-0.012437256,0.015494836,-0.119771065,0.064008988,0.038391287,0.0743175,0.03670206,0.046782711,-0.170082785,-1.569075835,-1.539103234,0.574707504,1.311379929,-7.269385873,-6.737715439,-8.236469223,-7.871647652,-7.530812263,-5.97028479,-7.172757021,-4.434305125 -1295,R92G,0.01619548,0.019031882,0.012819025,-0.087046263,-1.714960669,-0.060118521,-0.002349509,0.034740468,-0.049294241,0.020668392,0.017395372,-0.004160498,0.029798547,-0.012189748,-0.161902777,-1.68155848,-1.748362857,0.596479557,1.307477768,-6.51556158,-5.90240667,-7.291848145,-7.260743431,-7.062835983,-5.059973671,-6.637216627,-4.118027833 -1296,R92F,-0.054596324,0.030921571,-0.007493579,-0.052940994,-0.302908098,-0.009861701,-0.097965763,-0.011226885,-0.100613733,0.005772437,0.056070704,-0.001364175,-0.013622982,-0.002331027,-0.10355096,-0.195704018,-0.410112177,1.081654945,1.8600571,-5.891791014,-5.904228653,-7.256538071,-6.277097458,-5.777193405,-4.243897484,-5.54054542,-4.096410052 -1297,R92I,0.000744773,-0.009399505,0.063025905,-0.015121806,-0.036945939,-0.0951893,-0.092134099,0.093623645,-0.058526966,-0.022507925,0.003708915,0.065337087,0.060714723,0.00679796,-0.037041571,0.020260078,-0.094151955,1.069686565,2.61208164,-4.672584721,-4.742434875,-6.666088318,-4.353712654,-4.802012344,-2.798675415,-4.944547964,-2.176008493 -1298,R92H,0.031071084,0.119874741,0.024042968,-0.028964305,-0.103741082,-0.036856113,0.03264855,0.029493618,-0.100295518,0.033087198,0.206662283,0.009694169,0.038391766,0.002241957,-0.060170567,-0.135323863,-0.072158301,1.526820362,2.38409496,-3.53959453,-3.494449394,-3.941037521,-4.222607826,-2.910080002,-3.129797905,-4.970139946,-2.981224921 -1299,R92K,0.058331875,0.098932352,0.049226232,0.047867058,0.025212107,0.004889773,0.055693551,0.060970198,-0.077911211,0.089501311,0.108363392,0.044465221,0.053987242,0.049606012,0.046128103,0.085050022,-0.034625808,1.085829812,2.977637993,-3.189076111,-2.845110336,-3.758185371,-3.721832352,-3.80005986,-1.820192635,-4.063320022,-0.712624122 -1300,R92M,-0.016017454,-0.00151728,0.008420658,-0.051829907,-0.042024153,-0.090050544,-0.068806412,0.036771505,-0.012782756,-0.027071481,0.024036921,0.045946767,-0.029105452,-0.005988023,-0.09767179,0.023790826,-0.107839132,1.229112177,2.776510943,-5.058031693,-4.600204323,-6.992193695,-5.670878448,-5.464441902,-2.562440094,-5.573532002,-2.078508676 -1301,R92L,0.002988863,0.033411067,0.005582827,-0.025985269,-0.044805637,-0.06161556,0.000854523,0.005123202,-0.045036346,0.01217925,0.054642883,0.018211585,-0.007045931,-0.006188931,-0.045781607,-0.026007318,-0.063603956,1.671448915,3.643209181,-4.618163457,-3.81513678,-6.296243782,-5.323698936,-4.631976997,-3.023760788,-4.795400597,-1.722096549 -1302,R92N,0.023811185,0.057440782,0.009103993,-0.000378256,-0.266378004,-0.003606916,0.005327039,0.042295331,-0.082965768,0.035128873,0.07975269,0.046974003,-0.028766017,0.005462574,-0.006219086,-0.177220612,-0.355535396,1.355919774,2.133455404,-5.694545618,-5.071522301,-6.983017464,-6.647480461,-5.516918251,-4.253789612,-5.982278946,-3.156443377 -1303,R92Q,0.05295647,0.035158665,0.028091881,0.023782553,-0.112583396,0.001161048,0.027516227,0.078396713,0.001346553,0.011537368,0.058779962,0.023719814,0.032463947,0.008355141,0.039209965,-0.049159134,-0.176007657,1.3068407,2.527913776,-4.054557207,-3.416456375,-5.473992546,-4.224748161,-4.097145248,-3.060443703,-5.111399461,-1.605470049 -1304,R92P,0.027726756,0.071519341,0.047272541,0.017053734,-0.997423642,0.00615767,0.004836391,0.050617121,-0.084588705,0.022100219,0.120938463,0.039957345,0.054587736,0.0062435,0.027863968,-0.738292352,-1.256554932,0.769008353,1.40133507,-3.675499744,-3.283137505,-3.393010422,-5.374421196,-4.587670692,-1.739258904,-4.531892509,-0.947335783 -1305,R92S,0.033265449,0.050078673,0.01158973,-0.022563182,-0.379494693,-0.006331725,0.019463649,0.047067249,0.014575487,-0.013259276,0.113416622,-0.01731329,0.040492749,-0.039427722,-0.005698642,-0.281363554,-0.477625831,1.326018949,1.912604007,-3.744684401,-2.771876694,-4.623070885,-5.446083412,-3.141303108,-2.741087906,-4.426371704,-1.552332475 -1306,R92T,0.008648039,0.040669226,0.022357452,-0.030511688,-0.029915213,-0.090280131,-0.050383826,0.067679903,-0.019934973,0.033441198,0.047897253,0.067260615,-0.022545711,-0.016070838,-0.044952537,0.016771794,-0.076602219,1.172144321,2.639365773,-3.488810086,-3.048537949,-4.304962959,-4.590287239,-3.121232109,-2.379030174,-3.586286846,-1.08204136 -1307,R92W,0.022277446,-0.023962126,0.035816508,0.006838099,-0.434074301,0.01997028,0.034214989,0.010339902,-0.071046132,-0.049432857,0.001508605,0.053167385,0.01846563,0.009580414,0.004095784,-0.278668812,-0.58947979,1.107573596,1.774359031,-6.833058815,-6.583540245,-7.633850197,-7.16811515,-7.157276955,-5.622511528,-7.058713057,-5.149445707 -1308,R92V,0.021690624,0.030863001,0.03761103,-0.038880752,-0.051775185,-0.049594441,0.002897334,0.040483914,-0.026783092,-0.017132959,0.078858961,0.022226976,0.052995084,-0.00845658,-0.069304923,0.000861334,-0.104411704,1.231685683,2.676286906,-3.573799747,-3.674527771,-5.340761734,-2.70908857,-4.020242096,-2.124378563,-4.032084054,-0.911518376 -1309,R92Y,0.12528215,0.139720665,0.133774451,0.020753554,-0.049946375,-0.034055132,0.048149711,0.202414589,0.033979814,0.05400671,0.22543462,0.113645533,0.153903369,0.010916165,0.030590943,-0.096883039,-0.00300971,1.122556846,2.177862172,-6.487003258,-6.143374832,-8.037272881,-6.655966858,-7.161269676,-4.437132042,-7.65887629,-4.79215794 -1310,I93A,0.061037032,0.109238358,0.095648303,-1.266763837,-1.960784664,0.080064377,0.097149961,0.024924103,-0.086287533,0.130303996,0.08817272,0.048357201,0.142939405,-1.168394752,-1.365132921,-1.729174023,-2.192395304,3.006670199,2.242778209,-6.438436014,-6.421102303,-6.4257481,-5.975035736,-8.096242683,-5.274051247,-5.419369782,-3.785656076 -1311,I93C,-0.08862582,0.026995981,0.040232869,-0.610789686,-2.445633448,0.296428754,-0.045889663,-0.131361977,-0.041324726,0.08982659,-0.035834628,0.131420864,-0.050955126,-0.301616032,-0.919963339,-2.17091332,-2.720353575,1.255544213,1.307548263,-9.52363549,-9.459982101,-9.218260773,-11.10804194,-9.790346176,-8.041546463,-8.0455945,-6.027269829 -1312,I93E,0.072400746,0.068569232,0.077051975,-1.162497981,-2.328514781,0.09694108,0.10010451,0.044696981,-0.058727919,0.092668185,0.044470278,0.02165553,0.13244842,-0.990401941,-1.334594021,-1.974783212,-2.682246349,2.198145596,1.546592358,-8.761174513,-8.320303711,-8.554023643,-9.523994415,-10.01853043,-7.38902037,-6.59492293,-5.522805684 -1313,I93D,0.028726936,0.01416216,-1.377755769,-2.262617452,-2.531716041,0.110353058,0.084568141,-0.027114269,-0.139577949,0.004039978,0.024284341,-1.465437934,-1.290073603,-2.439537364,-2.085697539,-2.15047216,-2.912959922,0.625080795,0.040648933,-11.52578346,-11.55407478,-11.22533471,-12.99248003,-12.30706837,-9.549959427,-9.516183876,-9.435356603 -1314,I93G,-0.004848768,-0.022762212,-1.229219581,-2.067411457,-2.332829497,0.136786919,0.03135761,-0.041055145,-0.050965399,0.040220707,-0.08574513,-1.282531815,-1.175907347,-2.148848201,-1.985974712,-2.429658306,-2.236000687,0.556798846,0.06545246,-10.77337692,-10.97244062,-10.52698385,-11.06027406,-11.81401947,-9.493166603,-9.255026632,-8.254351544 -1315,I93F,-0.011748797,0.013327,0.033332611,-0.127120989,-1.905420019,0.096338738,0.009264731,-0.032762325,-0.073932492,0.142342676,-0.115688677,0.085663374,-0.018998153,-0.022148717,-0.23209326,-1.43551405,-2.375325988,0.463041086,1.311064338,-6.452957468,-6.420701324,-6.200675446,-9.425014885,-5.428243149,-4.790152534,-6.042227499,-2.775048522 -1316,I93H,0.045519467,0.114340244,0.007659687,-0.719483179,-1.874620321,0.112818824,0.111875184,-0.020836251,-0.080406337,0.131358416,0.097322072,-0.071745673,0.087065046,-0.327212319,-1.111754039,-2.19043546,-1.558805181,1.381604574,1.307700142,-9.286875352,-9.930239143,-8.664343536,-11.59463589,-8.737560692,-7.507597504,-7.022177961,-3.551168362 -1317,I93K,0.006783368,0.103103494,0.074804032,-1.603699318,-2.628070413,0.071305974,0.047476304,-0.033909569,-0.038375831,0.132706587,0.073500401,0.073856583,0.075751481,-1.329644755,-1.87775388,-2.295852057,-2.960288768,0.76053415,0.723942538,-8.768377151,-8.875477242,-8.32100502,-9.003940361,-9.541783669,-8.099679466,-7.201274764,-5.522805716 -1318,I93M,0.03931536,0.053784667,0.060687749,0.011312835,-0.198821455,0.117997346,0.050258432,0.028372287,0.042085322,0.078033344,0.029535989,-0.024904236,0.146279734,-0.063313431,0.085939101,-0.219405253,-0.178237657,1.472246367,2.14117482,-4.558236092,-4.447794334,-4.453969528,-5.228156578,-4.443018257,-4.21824176,-5.106339411,-2.918540079 -1319,I93L,0.063543481,0.068265429,0.056439041,-0.018117044,0.009083017,0.039754894,0.068267908,0.058819053,-0.03133549,0.097250799,0.039280058,-0.003007744,0.115885825,-0.093452089,0.057218001,-0.027125583,0.045291617,1.338492354,2.571581711,-2.98749124,-2.894065186,-2.585184685,-4.239575188,-2.60090744,-2.617723701,-3.466693802,-0.582278519 -1320,I93N,0.108282202,0.146553253,-0.043318316,-1.563456904,-1.829985674,-0.000315506,0.112799543,0.10376486,-0.092124879,0.175722118,0.117384388,0.003842031,-0.090478662,-1.737943215,-1.388970592,-2.227029262,-1.432942085,-0.170565839,0.668172263,-9.981471384,-10.30947153,-9.896378754,-11.26279074,-10.42028214,-8.018433762,-7.921620836,-6.027269843 -1321,I93Q,0.01416945,0.057008333,0.077859708,-0.313567194,-1.654153896,0.074734333,0.028830527,-0.000491628,-0.085356921,0.110783494,0.003233172,0.048778025,0.106941391,-0.222757219,-0.404377168,-1.871544108,-1.436763683,1.133685409,1.327333361,-9.09600806,-8.681132202,-8.67726754,-10.04222624,-9.799269943,-8.280144371,-6.806901641,-5.503169431 -1322,I93P,0.040158812,0.088148172,-0.890884166,-1.716071084,-2.827592355,0.168781199,0.086552354,-0.006234731,-0.082824393,0.064160244,0.1121361,-0.848203376,-0.933564956,-1.537872073,-1.894270095,-2.59122955,-3.063955159,2.333422203,1.198497118,-10.37183423,-10.59605161,-10.01594638,-11.26768307,-10.9713285,-9.008161583,-8.530182233,-6.959227195 -1323,I93S,0.00228312,0.052066459,-0.137030074,-1.547728334,-2.278966567,0.07369431,0.028544795,-0.023978555,-0.03053551,0.066374037,0.03775888,-0.068640522,-0.205419626,-1.456917159,-1.638539508,-2.122094465,-2.435838668,1.366828481,0.787478446,-8.013927866,-7.815535835,-8.566603958,-8.054255066,-9.783204269,-5.850040199,-6.752208475,-5.511046595 -1324,I93R,0.027995575,0.057986145,-0.044404622,-1.508261534,-2.473268585,0.141295561,0.076347862,-0.020356712,-0.048621954,0.083482926,0.032489363,-0.031063759,-0.057745485,-1.43067549,-1.585847578,-2.372059207,-2.574477963,0.867607538,0.722918527,-8.680274438,-9.236244316,-7.725671906,-9.846821228,-8.778345512,-7.81428923,-6.295281675,-3.772880839 -1325,I93T,0.056943104,0.077423485,0.055443864,-0.68674362,-1.958171757,0.058535812,0.107611581,0.006274627,-0.128350337,0.073542952,0.081304017,-0.00295154,0.113839267,-0.401847517,-0.971639722,-1.770111393,-2.146232121,1.581635333,1.412887036,-5.857366466,-5.74448484,-6.051652214,-5.074427765,-7.918670326,-4.497597183,-5.00545612,-3.518235515 -1326,I93W,0.017348563,0.048124676,0.047648164,-1.350506533,-2.628955372,0.008206831,0.055587666,-0.020890541,-0.069299268,0.08245324,0.013796111,0.015292881,0.080003447,-1.415943206,-1.285069859,-2.683180503,-2.57473024,0.634552788,0.707012973,-9.209098218,-9.214653893,-8.855229118,-11.46576144,-8.917599518,-7.592247116,-7.201778448,-4.988119723 -1327,I93V,0.064060271,0.069159089,0.056236371,0.013388793,0.051135263,0.087801151,0.070496317,0.057624224,-0.119817759,0.077962296,0.060355881,0.026154548,0.086318194,-0.062788396,0.089565982,-0.013923324,0.116193849,1.159011109,2.468212931,-1.252095132,-1.166196327,-1.046139633,-1.506374168,-1.791257851,-0.750507683,-3.091617779,0.041563895 -1328,I93Y,0.014565831,0.108757777,0.040259686,-0.010597841,-1.934341136,0.090951722,-0.016730135,0.045861797,-0.135489231,0.083951745,0.133563808,-0.048636582,0.129155954,-0.021939872,0.00074419,-1.272786753,-2.595895519,0.659395373,1.330672208,-8.123172527,-8.55922361,-7.811484398,-11.64892598,-6.618354515,-5.97787413,-6.369696619,-2.334561872 -1329,H94A,0.008190887,-0.020863359,0.006116085,-0.035357604,-0.08015141,0.024509881,0.006654877,0.009726896,0.006926339,-0.066661521,0.024934804,-0.050348388,0.062580557,-0.035545391,-0.035169817,-0.138987189,-0.021315631,1.271341103,2.12557449,0.047161813,0.292483521,-0.669142799,0.022370888,-0.738123199,1.328220657,-2.070580143,-0.285104351 -1330,H94C,-0.006272846,-0.038981483,-0.01146102,-0.01472634,-1.083906813,0.10447131,0.027173059,-0.03971875,-0.005016273,-0.033550259,-0.044412706,-0.069788868,0.046866828,-0.022917418,-0.006535262,-0.94034963,-1.227463995,0.86562072,1.389362405,-3.562857079,-3.436966164,-3.721215935,-4.193056969,-3.759717552,-2.703328774,-5.498467096,-3.609585763 -1331,H94E,0.040966153,-0.001807475,-0.038732702,-0.004739744,-0.062243135,-0.071911772,0.031963845,0.04996846,-0.022360038,-0.040554013,0.036939063,-0.086107606,0.008642203,-0.036395111,0.026915624,-0.093218191,-0.031268078,1.315768198,2.266309884,-0.292440047,0.026749672,-0.988118248,-0.809830536,-0.901876083,1.210874962,-2.864283371,-0.327817181 -1332,H94D,0.041547262,-0.02301181,0.000617414,-0.053304147,-0.218190842,0.061392477,0.040862874,0.042231649,-0.007345121,-0.113894275,0.067870655,-0.070951638,0.072186465,-0.112196537,0.005588243,-0.28989363,-0.146488054,1.530220618,2.062997791,-1.665114725,-1.661470276,-2.845548897,-1.6289506,-2.458661949,0.269058098,-3.660682385,-1.427719265 -1333,H94G,0.032364871,-0.026073076,-0.006642724,-0.032364749,-0.283787057,0.022033719,0.047526147,0.017203595,-0.011402526,-0.030579997,-0.021566154,-0.055186444,0.041900997,-0.062420144,-0.002309353,-0.276372923,-0.29120119,1.597199518,2.143681705,-1.436057375,-1.62010498,-2.099981453,-0.73204657,-2.582020714,-0.146133156,-3.030091271,-2.375201654 -1334,H94F,0.037794486,-0.033495889,-0.012454825,-0.004578771,-0.050553048,0.001811161,0.022443431,0.053145541,-0.012194343,-0.072943816,0.005952038,-0.072350848,0.047441198,-0.034031106,0.024873565,-0.12200838,0.020902285,1.286626118,2.174956232,-2.283855458,-2.175336823,-2.965018158,-2.653693199,-1.467953545,-2.157275566,-4.04540057,-0.999281398 -1335,H94I,0.023113708,-0.082947921,-0.045549782,-0.032439173,-0.073751089,-0.051684783,0.022116369,0.024111047,-0.001645049,-0.0684182,-0.097477641,-0.042508902,-0.048590662,-0.064440235,-0.000438111,-0.097129853,-0.050372324,1.358286856,2.328034385,-1.350378624,-1.012150055,-1.150470863,-2.099676453,-1.955564606,-0.534031143,-3.387062826,-0.9601009 -1336,H94K,0.063329593,-0.028654479,-0.022433307,-0.005152453,0.006742309,-0.029457988,0.049769602,0.076889584,-0.011331303,-0.079263045,0.021954088,-0.082003335,0.037136721,-0.042852363,0.032547457,-0.044049493,0.057534111,1.377425088,2.400084896,0.620693503,0.740410751,1.299262024,0.302712112,-0.627642494,1.388725121,-1.049212673,-0.504089911 -1337,H94M,0.092507305,-0.049155555,0.040542876,0.012545546,-0.035634476,-0.047752776,0.094126654,0.090887955,-0.018930009,-0.074330682,-0.023980427,-0.062272497,0.143358249,-0.056641755,0.081732846,-0.10421939,0.032950438,1.274930861,2.193197056,-1.20655701,-1.340002357,-1.081312401,-1.420315895,-1.66887516,-0.522279236,-2.72030051,-2.029179644 -1338,H94L,0.041418818,-0.021860263,0.019448254,0.014861906,-0.031465014,-0.019384134,0.041373533,0.041464103,0.051710046,-0.015151543,-0.028568982,-0.02530835,0.064204857,-0.002358339,0.032082151,-0.04215052,-0.020779508,1.312288508,2.527666673,-0.583149619,-0.733327728,-0.729720123,-1.256407196,-0.417273384,0.220980339,-2.404641127,-0.456164521 -1339,H94N,0.04967761,-0.064632036,-0.019856274,-0.034212868,-0.121656165,-0.020537062,0.06190845,0.037446769,-0.027623991,-0.082529514,-0.046734558,-0.091712368,0.051999821,-0.095499939,0.027074204,-0.132913618,-0.110398711,1.496222659,2.296015638,-1.595607748,-1.595626671,-1.690033569,-1.644319237,-2.246903191,-0.801156075,-3.083108687,-2.30969854 -1340,H94Q,0.026126791,0.01638219,-0.006870919,0.027865102,-0.014702428,0.028827756,0.037893718,0.014359863,0.076341206,-0.046058588,0.078822968,-0.043849414,0.030107577,0.002618206,0.053111998,-0.078093573,0.048688718,1.261419158,2.299702064,-0.001219711,0.253184029,0.492977051,-0.359717712,-0.866521164,0.47397924,-1.754796976,-1.416390507 -1341,H94P,0.012941107,-0.032037707,-0.027974991,-0.030031462,-0.530404004,-0.030228652,0.036896754,-0.01101454,-0.033298468,-0.053529065,-0.010546349,-0.07458868,0.018638699,-0.046142717,-0.013920207,-0.470286975,-0.590521033,1.403902652,1.78580415,0.326791032,0.735918167,0.166367188,-0.587603119,-0.436643021,1.755915947,-2.248804732,0.27320843 -1342,H94S,0.061998537,-0.016005265,0.031098896,-0.001345599,-0.055668842,-0.010948113,0.076957272,0.047039802,0.005446486,-0.027944638,-0.004065892,-0.025227003,0.087424794,-0.023954324,0.021263126,-0.095702109,-0.015635574,1.538479399,2.493472418,0.216786093,0.741620232,0.15094841,-0.296599609,-0.496263184,0.984224617,-1.959436361,-0.462944541 -1343,H94R,0.040591989,-0.045977258,0.007388863,-0.002736263,-0.03804817,-0.01629592,0.043076134,0.038107843,0.020170616,-0.046142014,-0.045812501,-0.039603605,0.054381331,-0.025310362,0.019837837,-0.03844372,-0.037652619,1.457469271,2.677032327,0.842006409,0.83183326,0.819648232,1.222389809,-0.188577705,1.524738449,-1.738058654,0.602780536 -1344,H94T,0.02456609,-0.029347339,-0.014421746,-0.022744183,-0.049445233,0.041544953,0.064000112,-0.014867933,-0.021558775,-0.046355633,-0.012339044,-0.069368923,0.040525431,-0.037296703,-0.008191662,-0.067247696,-0.03164277,1.349209593,2.375209477,1.072623405,1.745396797,0.944540489,0.627955826,0.025415955,2.019807961,-1.229417635,1.200727691 -1345,H94W,0.066036861,0.00686067,0.020244798,0.006537181,-0.00306571,-0.041853529,0.053395032,0.078678689,0.040661334,-0.020087594,0.033808934,-0.049201088,0.089690684,-0.046324162,0.059398523,-0.05942961,0.053298191,1.491416527,2.520370178,-4.509281258,-4.436768501,-5.147528625,-4.870155151,-4.262458908,-3.829495102,-5.381376577,-4.191798752 -1346,H94V,-0.000159244,-0.058362327,-0.009146795,-0.021079719,-0.046366569,-0.012798674,0.005811352,-0.006129839,-0.026702928,-0.082234321,-0.034490333,-0.09333931,0.07504572,-0.042387057,0.00022762,-0.113231241,0.020498103,1.494608538,2.298426105,-0.489853593,0.120786804,-0.347753159,-1.272592705,-1.344590912,0.394882004,-2.670859345,0.110766067 -1347,H94Y,0.067546288,-0.038803866,0.000900588,-0.000901168,-0.046653887,0.014666669,0.084896931,0.050195644,0.106965366,-0.055723643,-0.021884089,-0.041176998,0.042978173,-0.028474837,0.026672501,-0.080862163,-0.01244561,1.181596636,2.202629343,-2.45,-2.492919884,-3.442111877,-2.680290672,-1.3748181,-2.259859467,-3.776125199,-1.541682938 -1348,Y95A,-0.087700836,-0.056902574,-0.010219716,-1.614028914,-2.335377871,0.002360637,-0.072638544,-0.102763127,-0.050580047,-0.015841525,-0.097963622,-0.015841525,-0.004597906,-1.226193492,-2.001864336,-2.212873844,-2.457881897,0.750566346,0.733658349,-12.08303249,-11.61021188,-11.68103632,-12.13920632,-13.6549644,-11.32974354,-6.711502198,-3.3058962 -1349,Y95C,-0.07032269,-0.037206404,-0.360385767,-1.423772185,-1.646643046,0.023619643,-0.050988348,-0.089657031,-0.070934073,-0.02725733,-0.047155478,-0.24289109,-0.477880443,-1.577791417,-1.269752952,-2.506479822,-0.786806269,1.339068178,0.774209275,-11.02826976,-11.38453505,-11.03307596,-10.56766299,-12.54632819,-9.609746605,-7.669257562,-4.246166911 -1350,Y95E,-0.100184817,-0.298628637,-1.611927518,-2.420311099,-2.401496858,-0.065607745,-0.077015184,-0.123354449,-0.047349562,-0.037981195,-0.559276079,-1.758140499,-1.465714536,-1.971215324,-2.869406874,-2.355835685,-2.447158031,0.645593292,-0.022441454,-12.76149944,-13.17594809,-12.41757231,-12.35140285,-14.44701604,-11.4155579,-8.390911728,-5.677633867 -1351,Y95D,-0.08025339,-0.524754997,-2.239953082,-2.320914233,-2.540660619,-0.140636476,-0.050835271,-0.109671508,-0.031612256,-0.404849884,-0.644660109,-1.804955955,-2.674950208,-1.841939521,-2.799888944,-2.101621145,-2.979700093,4.229718639,2.462807461,-12.51202077,-12.84462182,-11.97595287,-11.9550758,-14.22686337,-11.55758999,-8.27892695,-6.073940624 -1352,Y95G,0.035023855,0.010731825,-0.043230041,-1.285856915,-2.275559344,-0.042499969,0.054304691,0.015743018,-0.068450148,-0.010964017,0.032427667,-0.067196065,-0.019264017,-1.510719812,-1.060994018,-2.117188922,-2.433929766,0.644768291,0.702607311,-13.88728156,-14.04757825,-13.78844032,-13.712131,-15.48557522,-12.40268303,-9.077273115,-6.735138178 -1353,Y95F,0.005928239,-0.007574703,-0.016208142,0.015282266,0.001701839,-0.016869734,-0.029046564,0.040903042,-0.024569602,-0.010336963,-0.004812443,-0.022995328,-0.009420956,-0.010553191,0.041117722,-0.012374649,0.015778326,1.089169871,2.420388502,-2.403114738,-2.027114235,-2.409318344,-3.484636406,-2.069448074,-2.025056633,-2.693370883,-1.169213456 -1354,Y95I,-0.057234798,-0.033562878,-0.011516266,-0.031686493,-0.08484952,-0.027164544,-0.113849009,-0.000620587,-0.076801332,-0.070236964,0.003111208,-0.087749879,0.064717347,-0.028363264,-0.035009721,-0.177103583,0.007404544,1.506929334,2.209819059,-5.495317018,-5.690044769,-5.1216605,-5.751103546,-7.679687927,-3.234088348,-3.205152771,-0.129919317 -1355,Y95H,-0.091763437,-0.002226713,-0.015098083,-0.692949887,-1.783828991,0.018856915,-0.092935729,-0.090591145,-0.037039529,0.045763607,-0.050217033,0.00483025,-0.035026416,-0.337533543,-1.04836623,-1.749212137,-1.818445845,1.463858041,1.391535989,-9.28082283,-10.07584953,-9.245530457,-8.874613678,-10.03448234,-8.173638145,-8.422618133,-6.73301239 -1356,Y95K,-0.192380133,-0.233460229,-1.429617359,-2.178474562,-2.699250944,0.024596145,-0.139988672,-0.244771593,0.029889615,-0.062946426,-0.403974032,-1.27246144,-1.586773277,-2.309445007,-2.047504116,-2.393035372,-3.005466515,0.906101764,0.103353275,-13.31574802,-13.79023117,-13.41114806,-12.97895482,-15.35274277,-11.04566329,-9.840817797,-9.092961316 -1357,Y95M,0.000388289,0.030030351,0.03807319,0.027107456,-1.705062055,-0.082417572,-0.002509281,0.003285859,-0.008644679,0.022011049,0.038049652,0.019063813,0.057082567,-0.031653529,0.085868441,-1.432261995,-1.977862114,0.668347301,1.322520938,-10.08700448,-10.32920718,-10.53441329,-10.36062302,-11.61988777,-7.590891136,-6.439095646,-1.998974396 -1358,Y95L,-0.096392728,-0.026333413,-0.029250362,-0.028171676,-0.912806239,-0.011345719,-0.140664863,-0.052120593,-0.11341301,-0.00274069,-0.049926135,-0.027073268,-0.031427455,-0.038334513,-0.018008839,-0.630697481,-1.194914997,1.135663083,1.551840374,-7.468680336,-7.971851509,-8.193439468,-7.425380211,-8.127531685,-5.625198807,-4.455425847,-0.259887795 -1359,Y95N,-0.132928592,-0.11501768,-1.163358974,-2.202547099,-2.635277852,-0.165013877,-0.078323583,-0.187533601,-0.07933708,-0.008383079,-0.221652281,-1.179510918,-1.147207029,-1.956857174,-2.448237024,-2.341477535,-2.929078169,2.359553468,0.858233032,-12.6706176,-13.18340276,-12.96967202,-11.91582143,-14.58191129,-10.7022805,-9.840817797,-9.092961316 -1360,Y95Q,0.081548506,0.073689654,-1.090896945,-2.04595211,-2.566728492,-0.073134257,0.080454701,0.082642311,-0.102863279,0.063636787,0.08374252,-1.208743621,-0.973050269,-1.914733968,-2.177170252,-2.174415592,-2.959041392,4.019261089,2.568060487,-12.38382109,-12.90495104,-12.35305533,-11.80426182,-14.68496329,-10.17187396,-8.245324832,-5.394011011 -1361,Y95P,-0.05235467,-0.026495533,-0.014449066,-0.905083713,-1.99029461,-0.063863156,-0.053248147,-0.051461193,-0.072198277,0.005596154,-0.05858722,-0.028607452,-0.00029068,-0.671360686,-1.138806739,-1.834132297,-2.146456922,1.995406414,1.530036062,-13.01048665,-12.99487713,-13.05487712,-12.76651793,-14.6343652,-11.60179586,-7.847034962,-4.388450718 -1362,Y95S,-0.083270224,-0.055407662,-0.587803647,-1.569073066,-2.125006547,-0.038202556,-0.072605052,-0.093935395,-0.093957776,-0.018113951,-0.092701372,-0.47644416,-0.699163134,-1.509204408,-1.628941724,-2.607035212,-1.642977882,1.939070296,1.010307579,-12.21303193,-12.23193242,-12.49315088,-11.19453429,-14.51744859,-10.62809349,-7.663282169,-4.590043145 -1363,Y95R,-0.045848397,-0.179156531,-1.238506919,-1.806388407,-2.553313625,0.001810866,-0.009860319,-0.081836474,-0.079417647,-0.090343699,-0.267969362,-1.478571321,-0.998442516,-2.328468244,-1.28430857,-3.0141186,-2.092508649,0.88203872,0.057384285,-11.44093877,-12.26467865,-11.90285524,-10.6346306,-13.54481596,-8.857713417,-7.731617653,-5.173065343 -1364,Y95T,-0.088938583,-0.014400067,-0.099823314,-1.55997798,-2.673178912,-0.016199543,-0.07878269,-0.099094476,-0.067801809,0.036241595,-0.065041729,-0.061332223,-0.138314405,-1.237033882,-1.882922078,-2.599377848,-2.746979975,0.830698865,0.738166449,-12.16538674,-11.96817904,-12.19053334,-12.4604848,-13.83311046,-10.37462605,-7.114778026,-4.283929019 -1365,Y95W,-0.021560606,0.049847118,0.020868366,0.017810347,-0.029609705,-0.099855594,-0.010881095,-0.032240117,0.0263474,0.119372104,-0.019677868,0.016858213,0.024878519,0.026195791,0.009424902,-0.000460077,-0.058759333,1.18511676,2.704507312,-5.057599092,-5.507011002,-6.810774857,-3.972029121,-4.213856903,-4.784323578,-4.415219438,-2.190172783 -1366,Y95V,-0.061207329,-0.054609064,-0.002049376,-0.049316092,-1.178690744,-0.014840672,-0.123815885,0.001401227,-0.031122876,-0.049768318,-0.05944981,-0.08185119,0.077752439,-0.102559522,0.003927339,-0.829003949,-1.528377539,1.498939425,1.658822683,-6.557820639,-6.385235779,-6.959621147,-6.057320824,-8.014536346,-5.372389099,-5.021173484,-0.148963985 -1367,S96A,-0.001867401,0.007803929,-0.01046151,0.011749338,-0.003642064,-0.038081264,-0.010412741,0.006677939,-0.216419998,-0.017897031,0.033504888,-0.040004224,0.019081205,-0.007493279,0.030991954,-0.01973517,0.012451042,1.208810791,2.514666621,-1.278011378,-1.293539932,-1.420447662,-0.722442734,-1.509714279,-1.443912285,-2.726487498,-0.708799344 -1368,S96C,-0.053363309,-0.035995551,-0.048848929,-0.046647174,-0.716253046,0.101406944,-0.024722571,-0.082004047,-0.617820539,0.008825614,-0.080816715,-0.05911371,-0.038584147,-0.044005808,-0.04928854,-0.448188477,-0.984317615,1.571618666,1.942024772,-4.61375347,-5.061775848,-4.642606781,-4.803973343,-4.332905289,-4.227506088,-6.280401984,-4.015016151 -1369,S96E,-0.030868378,0.009039942,-0.016716492,-0.027475466,0.0282327,0.014722289,-0.030302088,-0.031434667,-0.061518038,0.031165313,-0.01308543,0.013430283,-0.046863267,0.011707883,-0.066658815,0.038965889,0.01749951,1.12939296,2.644671853,-1.396586819,-2.301422638,-1.530477394,-1.074048958,-1.034952988,-1.04203212,-2.544063136,-0.468436689 -1370,S96D,-0.049874941,0.008320542,-0.020242917,-0.049817663,-0.00321986,0.007999055,-0.034312307,-0.065437575,-0.362548034,0.043622865,-0.026981781,-0.00036753,-0.040118303,-0.026186969,-0.073448357,0.010053192,-0.016492912,1.210836264,2.558956564,-1.444315256,-2.52507412,-0.749983604,-1.977412346,-1.376665375,-0.592440834,-2.882405739,-0.38179571 -1371,S96G,-0.024905311,0.015297998,-0.001027734,0.005783417,0.037468031,0.013475941,-0.030233524,-0.019577097,-0.232214265,0.032033048,-0.001437052,-0.008812105,0.006756638,0.000484195,0.011082638,0.011110306,0.063825755,1.192579612,2.685602053,-0.744863864,-0.44022361,-0.795572701,-0.319081093,-2.062609932,-0.106831985,-2.994770781,-0.421997111 -1372,S96F,-0.015831486,-0.04016404,-0.055435258,-0.015341146,-0.106211683,0.022147146,0.003811732,-0.035474703,-0.420539981,-0.015399876,-0.064928203,-0.039660289,-0.071210226,-0.040048656,0.009366365,-0.061930484,-0.150492882,1.299251671,2.391722178,-5.899376051,-6.587656143,-5.292392838,-6.281559357,-5.105053238,-6.230218681,-6.969669674,-5.167124826 -1373,S96I,-0.040485662,0.034115543,-0.00927947,0.018133019,-0.082016154,0.044546573,-0.047815621,-0.033155703,-0.304556087,0.073995701,-0.005764615,0.034263639,-0.052822579,0.016702424,0.019563613,-0.041603853,-0.122428455,1.134415154,2.33787599,-4.409065103,-5.120394638,-4.553751411,-4.597449684,-3.928057114,-3.845672668,-5.648004482,-3.592603266 -1374,S96H,-0.067314641,-0.034136804,-0.01790189,-0.03643649,0.011625173,0.034795605,-0.062160685,-0.072468597,-0.119509985,-0.026564253,-0.041709354,-0.002355151,-0.033448629,-0.037422704,-0.035450275,0.00981028,0.013440066,1.25873652,2.620294268,-1.879159442,-2.063759216,-1.713103065,-2.373119385,-1.433165276,-1.812650269,-3.301202489,-1.720142968 -1375,S96K,0.011290257,-0.011418876,-0.008788753,-0.016388144,-0.002363227,0.000959937,0.019289143,0.003291371,0.707489833,-0.018335269,-0.004502483,0.004771081,-0.022348587,-0.023109601,-0.009666686,-0.019828496,0.015102042,1.255113711,2.517233646,-0.511834904,-0.563582542,-0.771599709,-0.752966438,-0.143220604,-0.327805229,-2.640425569,0.154671294 -1376,S96M,-0.055335216,0.018833219,0.005462531,0.002873301,-0.0196778,0.016606521,-0.055028779,-0.055641653,-0.362548034,0.069216344,-0.031549906,0.003985027,0.006940035,0.01127491,-0.005528308,0.026697778,-0.066053377,0.954757829,2.446325488,-3.963992102,-4.495159576,-3.657747467,-4.191444359,-3.478028625,-3.997580482,-4.976318379,-2.380560391 -1377,S96L,-0.01543998,0.010835811,-0.000405381,0.002699527,-0.025364385,0.03622999,-0.003850314,-0.027029646,-0.119509985,0.035085115,-0.013413494,0.01691705,-0.017727811,-0.005169299,0.010568353,-0.032215055,-0.018513714,1.206292786,2.495999607,-2.386765623,-3.526179642,-1.573074501,-2.951202126,-1.586982971,-2.296388878,-4.01691176,-1.484603564 -1378,S96N,-0.016254759,-0.022475986,-0.001846978,0.011931873,0.009597091,-0.01613118,-0.038361558,0.00585204,-0.324759473,-0.055259631,0.01030766,-0.035565808,0.031871852,-0.000774621,0.024638366,-0.021039896,0.040234078,1.543610422,3.106887046,-1.49374707,-1.813441177,-1.678669708,-1.946646545,-0.788955574,-1.241022347,-2.393704962,-1.344282278 -1379,S96Q,-0.033473393,-0.023366829,0.011022466,-0.02653964,0.048938316,0.039399807,-0.050603779,-0.016343006,-0.362548034,0.008306374,-0.055040032,0.003805158,0.018239774,-0.033430866,-0.019648413,0.020709743,0.077166889,1.280036616,2.710921859,-1.316956718,-1.328183952,-1.86609082,-1.170992157,-0.767831337,-1.451685326,-2.632282178,-0.84245369 -1380,S96P,-0.043877309,-0.001746513,-0.007789765,-0.021045379,-1.456086594,0.039891017,-0.022432009,-0.065322608,-0.033122666,0.014523594,-0.018016619,-0.004709567,-0.010869963,-0.001413187,-0.040677571,-1.397266294,-1.514906894,0.822119173,1.336818778,-2.221355354,-3.495847984,-2.777946533,-1.109350533,-1.309988503,-2.413643219,-3.598775005,-0.741627496 -1381,S96R,-0.028353079,-0.017692668,-0.011650031,-0.021686613,0.003768319,0.010297094,-0.025659188,-0.03104697,-0.178903637,-0.017893066,-0.01749227,-0.024280611,0.000980549,-0.02366,-0.019713225,-0.025080646,0.032617283,1.266887541,2.476383067,0.535323428,0.349915962,0.799129936,0.463973602,0.396005867,0.667591774,-0.732317948,0.280712999 -1382,S96T,0.0000586,0.007634001,0.010590375,-0.020313983,0.032250079,0.014165811,0.004663629,-0.004546483,0.211483234,-0.006167469,0.021435471,-0.011753862,0.032934611,-0.016943571,-0.023684395,-0.009761289,0.074261447,1.199214144,2.564123395,0.250449315,0.523665321,0.131489204,0.126006721,0.299737839,0.171347488,-1.233915839,0.852803525 -1383,S96W,-0.051347789,-0.030122277,-0.022056507,-0.027889759,-0.34578657,0.04836397,-0.002456749,-0.100238828,0.415603217,-0.001474463,-0.058770091,-0.014290712,-0.029822302,-0.019028701,-0.036750816,-0.279428354,-0.412144785,1.320101189,1.928781018,-6.284584436,-6.922490532,-5.555696739,-6.617023445,-5.700796768,-6.626914696,-7.845625234,-6.935128809 -1384,S96V,-0.05593132,-0.008019128,-0.047026306,-0.01739867,-0.031687321,0.037263485,-0.040657393,-0.071205247,-0.362548034,0.034222563,-0.050260818,-0.024063469,-0.069989142,0.013745425,-0.048542764,-0.010383308,-0.052991333,1.318602805,2.642984867,-3.012049365,-3.585797371,-3.447556633,-2.609452232,-2.649790749,-2.767649841,-4.291263542,-2.008247049 -1385,S96Y,-0.083757906,-0.045405409,-0.038051755,-0.041922628,-0.090141803,0.020060623,-0.066874639,-0.100641172,-0.408305524,-0.023087229,-0.067723588,-0.027158033,-0.048945477,-0.019377791,-0.064467464,-0.09270448,-0.087579126,1.347942272,2.262875996,-4.335690787,-4.712930237,-4.23008728,-4.6861716,-3.642913391,-4.406351425,-6.231547332,-3.14045519 -1386,Q97A,-0.01178375,-0.020786042,0.002297365,0.055621348,-0.019611956,0.041292018,0.025714023,-0.049281522,0.04408119,-0.019223291,-0.022348792,-0.003661046,0.008255776,0.002120941,0.109121754,0.012281097,-0.051505008,1.297655796,2.712141618,-1.412247394,-0.42550209,0.191414436,-2.040151443,-3.890543999,-0.896453873,-2.764545019,0.873521775 -1387,Q97C,-0.107345012,-0.017768939,-0.041538151,0.003076517,-1.576997734,0.16818346,-0.058892362,-0.155797662,0.074331421,-0.045696012,0.010158134,-0.044553978,-0.038522324,0.010978979,-0.004825946,-1.505676277,-1.64831919,0.725961384,1.323414735,-7.32499118,-6.31143457,-6.090348145,-8.439606857,-9.107682457,-6.675883873,-8.386624201,-6.441058645 -1388,Q97E,-0.063623807,-0.022325637,0.001899499,0.037051467,0.002158724,0.081328079,-0.025164256,-0.102083358,0.136780583,-0.002818989,-0.041832284,-0.016669531,0.020468529,0.009069001,0.065033932,0.022480002,-0.018162555,1.269608364,2.781116593,-0.537129779,-0.058132301,0.710468369,-1.239580681,-1.390954323,-0.707449959,-2.061800863,0.65790647 -1389,Q97D,-0.018227653,0.044454986,0.006432206,0.048878659,-0.002857923,0.113201851,0.028509721,-0.064965026,-0.001165372,0.109792437,-0.020882465,0.060584266,-0.047719855,0.036189708,0.06156761,0.058075862,-0.063791707,1.198917167,2.858142857,-3.033661952,-1.910598663,-1.835028305,-4.140161957,-5.095159035,-2.187361801,-3.950145627,-0.029194151 -1390,Q97G,-0.046372329,-0.003646744,0.012263541,0.052632021,-0.01401232,0.055798469,-0.025045401,-0.067699257,0.017072969,-0.001533267,-0.00576022,0.0060084,0.018518681,0.011893975,0.093370066,0.008296743,-0.036321383,1.543610422,3.106887046,-3.824718286,-2.639819641,-2.371761444,-5.298431686,-5.702301788,-3.111276871,-4.280951049,-1.53256485 -1391,Q97F,-0.027954389,0.007563676,0.018163898,0.076816406,-0.075288388,0.027087037,-0.046255789,-0.009652989,0.092413029,0.017488493,-0.002361141,-0.000337312,0.036665107,0.046196368,0.107436444,0.01378671,-0.164363486,1.159932201,2.655793289,-6.332944406,-4.938813789,-5.401170677,-7.958062126,-8.132553459,-5.234121979,-6.905060988,-4.037158822 -1392,Q97I,-0.082261301,-0.061406409,-0.118546134,0.000176779,-0.050842348,0.081288984,-0.00696037,-0.157562231,0.031813779,-0.053877924,-0.068934893,-0.092254829,-0.144837439,-0.029400806,0.029754363,-0.030129816,-0.071554879,1.134089548,2.388891689,-5.02927417,-3.833514175,-4.562556274,-6.373815666,-5.956702614,-4.41978212,-6.082620241,-2.564586313 -1393,Q97H,-0.038335157,-0.005533636,-0.023930157,0.020981771,-0.091936105,0.087968259,-0.008770824,-0.06789949,-0.001115859,0.004114023,-0.015181294,-0.040040721,-0.007819592,-0.025390671,0.067354213,0.020480178,-0.204352388,1.163459699,2.579968909,-3.713641293,-2.996035316,-3.026735413,-4.551973236,-4.972199165,-3.021263336,-5.43519128,-2.250006116 -1394,Q97K,-0.126185616,-0.000745218,0.045289667,-0.031884997,-0.010289612,0.037450519,-0.129459959,-0.122911272,0.09017402,0.073318568,-0.074809004,0.040341419,0.050237914,-0.012997924,-0.05077207,0.052986732,-0.073565955,1.098010228,2.749975142,0.155567873,0.591089355,0.723372887,-0.393737213,-0.332330948,0.189445282,-1.84543887,1.056956588 -1395,Q97M,-0.067446126,-0.048332581,-0.01690647,-0.017686759,-0.077931497,0.040252619,-0.045920329,-0.088971922,0.045675655,-0.030906345,-0.065758817,0.029652955,-0.063465894,-0.005445547,-0.02992797,-0.0582873,-0.097575694,1.546473607,2.938183126,-4.969837845,-4.187673988,-4.469774353,-6.31179303,-6.103762741,-3.776185112,-5.948318429,-3.036483399 -1396,Q97L,-0.028161022,-0.010277035,-0.030235466,0.021141949,-0.010569208,0.021105558,0.002858185,-0.059180228,0.089376746,-0.000920181,-0.019633889,-0.020907735,-0.039563196,-0.004544356,0.046828254,0.005393947,-0.026532363,1.130658869,2.487209058,-4.031868669,-3.200798729,-3.909027779,-5.476934372,-4.600824966,-2.9717575,-5.63322917,-2.235617769 -1397,Q97N,-0.084050113,-0.043539549,-0.014466392,0.03604303,-0.096146583,0.119263964,-0.002102753,-0.165997473,-0.020475915,-0.110978286,0.023899188,-0.01106775,-0.017865033,0.006619039,0.06546702,-0.051836342,-0.140456824,1.273551708,2.438066222,-3.499693753,-2.47664122,-2.819908951,-4.740303268,-4.479600693,-2.982014633,-4.63087206,-0.354847928 -1398,Q97P,-0.05300426,-0.048890939,0.002894927,0.020299373,-0.033617087,0.035344524,-0.041817999,-0.064190521,0.068123327,-0.005985857,-0.091796021,-0.020155524,0.025945377,-0.029888355,0.0704871,-0.000324686,-0.066909487,1.139198534,2.421196228,-1.895855524,-0.497716507,-0.655745949,-3.69503241,-3.220586174,-1.410196579,-2.74975932,0.842874219 -1399,Q97S,-0.038334711,-0.025954396,-0.010194942,0.057304561,-0.015191232,0.045280699,0.005589508,-0.082258929,0.052295806,-0.020424008,-0.031484784,-0.007081889,-0.013307995,0.023433189,0.091175932,0.018671557,-0.04905402,1.101222184,2.621088429,-2.026808734,-1.14127919,-0.307115646,-3.016372849,-3.629163399,-2.040112587,-3.528774483,-0.265720842 -1400,Q97R,-0.05173822,-0.027682987,-0.005709524,0.044221478,-0.025489968,0.047576151,-0.027706875,-0.075769564,0.115186463,0.010267207,-0.065633181,0.007776341,-0.019195388,0.018878261,0.069564694,0.022290196,-0.073270132,1.123902709,2.683513769,-0.832705711,-0.634364746,-0.096529015,-1.025385788,-1.921338661,-0.485910347,-2.104723149,0.714424365 -1401,Q97T,-0.033832614,-0.026347409,-0.017490861,0.037239475,-0.032345228,0.066863271,0.003338502,-0.07100373,0.088926587,-0.024937774,-0.027757043,-0.031973099,-0.003008623,-0.021786547,0.096265496,-0.020955939,-0.043734517,1.239348798,2.512211098,-3.016581023,-1.869804626,-1.635979866,-4.145479553,-4.679944023,-2.751697044,-3.904692295,-1.365166625 -1402,Q97W,-0.062078337,-0.049287777,-0.013915967,0.007019788,-0.079322043,0.048114653,-0.031138587,-0.093018087,0.09688724,-0.029755155,-0.068820398,0.032161028,-0.059992962,-0.025794532,0.039834107,-0.043496531,-0.115147555,1.386331502,2.59155476,-5.386335599,-4.313519882,-4.591717194,-6.754221947,-7.144302109,-4.127916862,-6.007852069,-3.090499608 -1403,Q97V,-0.015442054,0.012150015,0.008421494,0.045222625,0.021819069,0.057853798,0.01693819,-0.047822298,0.088777875,-0.003178059,0.027478088,0.011111802,0.005731185,0.017556313,0.072888936,0.027388016,0.016250121,1.211539417,2.763956726,-3.900015421,-3.017297806,-2.998132217,-5.06134536,-5.525716782,-2.897584938,-4.732161436,-1.751594875 -1404,Q97Y,-0.090245973,-0.014839269,-0.045435635,0.031308355,-0.089757123,0.04509579,-0.023865361,-0.156626585,-0.025854386,-0.009496026,-0.020182512,-0.004682466,-0.086188804,0.000207747,0.062408963,-0.041899597,-0.137614649,1.247006319,2.456622331,-6.154548969,-4.610100815,-5.350209641,-7.86407605,-8.227004013,-4.721354324,-6.769203571,-4.037158725 -1405,N98A,0.004424573,-0.014009134,-0.021701759,-0.036849619,-0.054690586,-0.01574315,-0.011678974,0.020528119,-0.221688318,0.0073099,-0.035328168,-0.033964612,-0.009438905,-0.042588905,-0.031110332,0.010200534,-0.119581706,1.16137238,2.560048067,0.781464713,1.201816544,-0.214228813,0.969553642,0.3014104,1.64877179,-1.912630785,1.984376224 -1406,N98C,0.081171246,-0.02226127,-0.071471747,-0.143726178,-1.668090614,-0.099336077,-0.047720689,0.210063181,-0.059352293,-0.001699753,-0.042822787,-0.057322146,-0.085621347,-0.066666433,-0.220785923,-1.563563726,-1.772617501,0.909002869,1.333090846,-4.195735045,-3.960493927,-5.020238495,-4.392549988,-4.093222969,-3.512169846,-5.575185635,-2.746509349 -1407,N98E,-0.060883854,-0.066025394,-0.045896015,-0.070355114,-0.091125567,-0.009761176,-0.098571992,-0.023195716,-0.09456552,0.003316587,-0.135367374,-0.037451164,-0.054340865,-0.070516471,-0.070193756,-0.009680459,-0.172570675,1.418178283,2.641941297,0.540609685,0.930905708,0.32034845,-0.049115028,0.334837814,1.16607148,-2.394245176,1.881546436 -1408,N98D,0.021104186,-0.002207332,-0.003625583,-0.031768604,-0.031768977,-0.020744895,-0.000919298,0.043127669,-0.168667241,0.043963792,-0.048378455,0.010519899,-0.017771065,-0.054078266,-0.009458942,0.037580881,-0.101118834,1.2552481,2.736244553,0.919744339,0.892757889,0.959958069,1.119556129,0.840999001,0.785450607,-2.037772905,1.617415587 -1409,N98G,-0.004499332,-0.041130433,-0.031414219,-0.058506797,-0.061982212,-0.012741225,-0.029592253,0.020593589,-0.089485995,-0.029756774,-0.052504091,-0.019080354,-0.043748083,-0.081964854,-0.03504874,-0.025529451,-0.098434972,1.401647666,2.585036644,-0.174039737,0.290592934,-0.320846657,0.13343605,-0.88938092,-0.084000092,-2.971876762,0.906377946 -1410,N98F,0.001768825,-0.007699978,-0.000203541,-0.034917647,-0.022139397,-0.042785635,-0.029281225,0.032818875,-0.142923736,0.005540664,-0.02094062,-0.012149764,0.011742682,-0.058555285,-0.011280009,0.015250317,-0.05952911,1.104579495,2.627155609,-4.654500285,-3.99240062,-5.819995842,-4.616950424,-5.231090187,-3.612064354,-5.006562509,-2.311884708 -1411,N98I,0.011351267,-0.028654446,-0.017715678,-0.046885398,-0.047687942,0.009490217,0.004414662,0.018287872,-0.0255355,-0.021791517,-0.035517374,-0.056541234,0.021109879,-0.083925794,-0.009845002,0.006112328,-0.101488212,1.101056876,2.457562682,-3.975110123,-3.836974701,-5.006561501,-3.358556221,-4.497249985,-3.176208206,-4.505271115,-1.652045349 -1412,N98H,0.015152871,-0.02890307,0.006697071,0.005904942,-0.049312425,-0.015938832,0.001066227,0.029239515,-0.165497194,-0.014048253,-0.043757887,0.002107567,0.011286574,-0.027808156,0.03961804,0.036741481,-0.13536633,1.145397144,2.602042605,-0.965591313,-1.391428795,-2.121643555,0.161796745,-0.571994667,-0.904686295,-2.828061811,-0.661646317 -1413,N98K,0.042041521,0.000741144,0.021190492,-0.011860271,-0.033608341,-0.037479537,0.030731922,0.053351119,0.079510447,0.003729933,-0.002247646,-0.005520767,0.047901751,-0.027342407,0.003621865,0.01930834,-0.086525022,1.258591366,2.702723941,0.202931544,0.841597626,-0.548608467,-0.198922386,-0.0575196,0.97811055,-2.927829976,1.025147372 -1414,N98M,-0.054674979,-0.056781706,-0.056999271,-0.09000504,-0.093436783,-0.018537924,-0.079602267,-0.02974769,-0.143843657,-0.042738438,-0.070824973,-0.056557352,-0.05744119,-0.101735352,-0.078274728,-0.014399035,-0.17247453,1.273993576,2.399096019,-4.637998022,-4.119321793,-5.663316032,-4.723223419,-5.223176445,-3.460952423,-5.606873679,-3.148986796 -1415,N98L,-0.023855184,-0.008639403,-0.015058771,-0.039489012,-0.050658885,-0.041127783,-0.03009783,-0.017612538,-0.166472721,0.02757634,-0.044855146,0.017809244,-0.047926785,-0.035112381,-0.043865642,0.032481804,-0.133799573,1.274576722,2.778318422,-4.20884799,-4.204166809,-5.330834785,-3.789281792,-4.348469147,-3.371487419,-5.568494152,-2.118202807 -1416,N98Q,-0.010719589,-0.027341094,-0.038164171,-0.060748666,-0.053535029,0.066418556,-0.013954269,-0.007484909,-0.217885264,-0.016053619,-0.038628569,-0.019971824,-0.056356517,-0.061540722,-0.059956609,0.008382872,-0.115452929,1.183781111,2.542245079,0.330404889,0.297806,0.051135941,1.166446564,-0.231368706,0.368004646,-1.565293439,0.22332183 -1417,N98P,-0.020158334,-0.008225111,-0.022395536,-0.033124086,-0.082870102,0.009425456,-0.043321128,0.003004461,-0.211514618,0.009947145,-0.026397366,-0.015658365,-0.029132707,-0.046745179,-0.019502993,-0.030364662,-0.135375541,1.198251735,2.327531613,-4.111570451,-3.862544655,-5.172904396,-3.883380997,-4.392539658,-3.246482552,-4.651656141,-0.670724134 -1418,N98S,-0.03598568,-0.009592535,-0.022248828,-0.035697131,-0.049634646,-0.025664537,-0.064334098,-0.007637261,-0.207357271,0.035978512,-0.055163582,0.004371674,-0.04886933,-0.048063392,-0.02333087,0.013192259,-0.112461551,1.187801133,2.555345227,1.04628614,1.426737839,0.982935432,0.317331047,1.362898384,1.141528,-1.250379407,1.900475956 -1419,N98R,0.006132288,-0.017207493,-0.015119109,-0.029459791,-0.043622887,-0.000939688,-0.012678571,0.024943147,-0.17411146,0.010778688,-0.045193674,-0.010840276,-0.019397942,-0.025212382,-0.0337072,0.023742546,-0.110988319,1.671448915,3.643209181,-0.069411771,0.1007183,-1.505371368,0.796562515,0.154301468,0.106730232,-2.991460728,0.361342275 -1420,N98T,-0.03565817,-0.018741746,-0.037001757,-0.02993934,-0.056332568,-0.025935203,-0.064812016,-0.006504323,-0.143113137,-0.005281109,-0.032202383,-0.010884443,-0.06311907,-0.031530725,-0.028347955,0.008916281,-0.121581417,1.149938831,2.549274354,-0.554833173,-0.26993206,-0.944186981,-0.874656433,-0.193412384,-0.491978004,-3.015290159,0.436962965 -1421,N98W,0.012140661,-0.019065927,-0.014553523,-0.057602724,-0.040330558,-0.015758444,-0.02665635,0.050937672,-0.202930445,0.013150384,-0.051282238,0.004926683,-0.034033729,-0.035019837,-0.080185611,0.024306665,-0.10496778,1.107887337,2.59724708,-6.085929366,-5.911582047,-6.731229904,-5.736607941,-6.599089142,-5.451137794,-7.91037194,-6.695511649 -1422,N98V,-0.041429824,-0.021845772,-0.022500507,-0.044302183,-0.048610582,0.019313927,-0.057592067,-0.025267581,-0.119427311,0.022829976,-0.066521519,-0.00022031,-0.044780704,-0.047845519,-0.040758846,0.046457312,-0.143678476,1.172144321,2.639365773,-3.307982587,-2.863842064,-4.365923309,-2.701400391,-4.267217934,-2.341529236,-4.183675522,-1.098257545 -1423,N98Y,-0.052824546,-0.040095601,-0.024513781,-0.035463022,-0.019943187,-0.161192221,-0.090916303,-0.014732788,-0.177696558,0.039404399,-0.119595601,0.001503289,-0.050530851,0.005792898,-0.076718942,0.038047919,-0.077934292,1.097788313,2.717351358,-3.841918619,-3.669326241,-5.249736496,-3.744020058,-3.761120567,-2.785389732,-5.093320008,-1.479884786 -1424,D99A,0.05969738,-0.037313322,0.028030612,-0.025900744,-0.161376064,-0.017801836,0.051124081,0.068270679,-0.013005686,-0.048973609,-0.025653035,-0.010398523,0.066459747,-0.033222944,-0.018578544,-0.163451945,-0.159300182,1.432700019,2.197139854,-4.23175918,-3.991547493,-5.450327667,-4.035530869,-2.46140387,-5.219986,-3.448876903,-2.832720173 -1425,D99C,0.257449568,-0.000131394,0.047169646,-0.576618337,-1.991657821,-0.078596162,0.077662647,0.437236489,-0.062960263,-0.055349153,0.055086366,-0.016990718,0.111330009,-0.306662657,-0.846574017,-1.818799213,-2.164516429,1.466399851,1.379950828,-9.41817417,-9.313141243,-11.42490857,-9.525401085,-7.391768341,-9.435651611,-7.893012146,-6.183850052 -1426,D99E,0.041193925,0.008852435,-0.006571978,-0.018170338,-0.052275571,0.030824424,0.046337926,0.036049924,0.035493464,-0.04289147,0.060596339,-0.053250486,0.04010653,-0.02691298,-0.009427696,-0.076077906,-0.028473235,1.314858748,2.331832241,-2.708839224,-2.195305862,-4.066515076,-2.671161079,-1.712688293,-2.89852581,-3.222577307,-1.812277586 -1427,D99G,0.01001503,-0.035958625,0.005166134,-0.03399626,-1.656499372,0.002235904,0.00811231,0.011917749,0.017117147,-0.089126563,0.017209313,-0.044526576,0.054858843,-0.022279685,-0.045712834,-1.620385305,-1.692613439,0.842042654,1.323853187,-6.785933836,-6.803525803,-8.108190697,-6.213188087,-5.190661934,-7.614102661,-5.638908394,-3.759315928 -1428,D99F,-0.063742016,-0.05460808,0.023652183,-0.062770108,-1.484216288,-0.001012625,-0.09551145,-0.031972582,-0.012489735,-0.112916511,0.003700352,-0.016287677,0.063592042,0.006021483,-0.131561699,-1.248010144,-1.720422432,0.7002605,1.336323267,-9.539319473,-9.643980988,-11.40240302,-9.35550396,-8.30620443,-8.988504974,-6.275229242,-3.825376879 -1429,D99I,0.003891849,-0.069217934,0.010444287,-0.01354972,-0.877720052,-0.000980141,-0.011553548,0.019337246,0.011402603,-0.113615015,-0.024820853,-0.073055549,0.093944123,-0.064649238,0.037549799,-0.625868277,-1.129571827,1.185030521,1.576904831,-8.602468781,-9.823257355,-9.644177597,-8.661802681,-6.732118645,-8.150987625,-6.409475691,-4.349427034 -1430,D99H,0.039733338,0.014870525,0.02323663,-0.023458897,-0.172785852,-0.023017148,0.038609508,0.040857167,0.103155634,-0.01424002,0.043981069,0.024666485,0.021806774,0.035249584,-0.082167378,-0.145605622,-0.199966082,1.443704994,2.323830588,-6.360419237,-7.263210526,-7.899694572,-5.833371689,-5.188454002,-5.617365395,-6.446489923,-3.244715812 -1431,D99K,-0.011158987,-0.036058634,0.004606321,-0.086114675,-0.700813663,0.019587476,-0.006958789,-0.015359185,-0.041138733,-0.094567408,0.02245014,-0.056562865,0.065775507,-0.018610797,-0.153618552,-0.475721626,-0.925905699,1.529843774,1.87293527,-5.356528409,-5.915688927,-7.659986694,-3.501007339,-4.994934509,-4.711024574,-5.216543729,-3.91408782 -1432,D99M,0.014362814,0.008897899,0.006360406,-0.052730501,-0.144838937,0.010476713,0.013809325,0.014916302,-0.008809655,-0.01980212,0.037597917,0.04130732,-0.028586509,-0.036820073,-0.068640928,-0.141419477,-0.148258396,1.485262542,2.319238645,-6.073796165,-7.721005402,-6.348201744,-5.896726723,-4.321337326,-6.081709633,-5.580931946,-3.434262598 -1433,D99L,0.06381155,0.001013681,0.019424334,-0.011030367,-0.589505055,0.011371614,0.046747624,0.080875476,0.046902817,-0.034518733,0.036546095,0.010497693,0.028350974,-0.001375913,-0.020684821,-0.489155204,-0.689854906,1.048477467,1.579124131,-7.681526038,-8.680904831,-9.351670448,-7.904357613,-5.532943596,-6.9377537,-5.940654443,-2.844714586 -1434,D99N,0.061149347,-0.024148244,-0.04954016,-0.028789322,-0.257325475,-0.059113535,0.090050254,0.032248439,-0.021952113,-0.091642215,0.043345727,-0.103505773,0.004425453,-0.011299165,-0.046279479,-0.252494705,-0.262156244,1.438567451,2.059079851,-4.547261252,-5.385747292,-4.949283432,-3.660800117,-4.285036667,-4.455438751,-4.514223828,-3.030382515 -1435,D99Q,0.101868984,0.064430179,0.068215427,-0.012286406,-0.076510138,-0.062970579,0.064791282,0.138946685,0.024431732,-0.037210507,0.166070864,0.020901576,0.115529277,-0.027663224,0.003090413,-0.168713363,0.015693088,1.557543936,2.327750822,-3.672040074,-3.91761692,-5.356920395,-3.430027138,-2.533621414,-3.122014503,-3.569376999,-2.885175669 -1436,D99P,0.017780245,-0.000674694,0.031433897,-0.633625052,-2.032132563,-0.036428736,0.016774155,0.018786334,0.046075573,-0.031597331,0.030247944,-0.005945605,0.068813398,-0.365062465,-0.902187639,-1.935153436,-2.12911169,1.451715323,1.351869571,-7.607034999,-7.87255098,-8.353636406,-7.909751076,-5.607567665,-8.291668869,-5.796579245,-4.703422496 -1437,D99S,0.059156313,-0.023519996,0.021995325,-0.021117292,-0.173502848,-0.003275804,0.078637328,0.039675298,0.02274548,-0.052976454,0.005936462,0.01438311,0.02960754,-0.016245831,-0.025988753,-0.204669702,-0.142335993,1.470013363,2.165898788,-5.242174524,-5.591190117,-5.906052147,-4.729450645,-4.042972618,-5.941207092,-4.939122278,-2.58330614 -1438,D99R,0.043124347,-0.009609758,0.02024732,-0.03447462,-1.245599476,-0.005196682,0.057492751,0.028755943,-0.009789434,-0.035857995,0.016638479,-0.012359902,0.052854542,-0.02679829,-0.04215095,-0.981713689,-1.509485263,0.737762057,1.362212404,-6.135891747,-6.72232869,-8.116874603,-5.306523651,-5.002279045,-5.531452744,-6.438932212,-3.05567356 -1439,D99T,0.045820717,-0.055323664,-0.02861519,-0.045525677,-0.409173528,-0.0175048,0.038851379,0.052790054,0.046331001,-0.081428322,-0.029219006,-0.070046259,0.012815879,-0.058927424,-0.03212393,-0.406164292,-0.412182763,1.531851368,1.945583381,-5.938374051,-6.495173615,-6.75727317,-5.660947441,-4.425627396,-6.352848633,-5.046618357,-3.815897498 -1440,D99W,-0.114648221,-0.089662891,-0.02026665,-0.02426897,-1.876323526,-0.007905995,-0.127657118,-0.101639324,-0.027246125,-0.018138471,-0.161187311,0.056028294,-0.096561594,0.048703465,-0.097241405,-1.676541614,-2.076105437,0.571382956,1.305859542,-9.552569899,-9.90162693,-11.29582437,-10.33617104,-8.245996933,-7.983230225,-7.82718039,-6.161939181 -1441,D99V,-0.022621959,-0.05738663,-0.021134105,-0.084733599,-0.354782275,-0.003846223,-0.044100115,-0.001143802,0.073828208,-0.080700142,-0.034073118,-0.039758952,-0.002509258,-0.072185381,-0.097281816,-0.325007591,-0.384556959,1.677386192,2.145671348,-6.270678418,-6.979615578,-7.103794594,-6.219352524,-4.772352646,-6.278276749,-4.412421203,-2.913571406 -1442,D99Y,0.053183579,-0.037141997,0.029745116,-0.04101803,-1.513458825,0.004249629,0.038617923,0.067749235,0.018550189,-0.039151341,-0.035132653,-0.00550998,0.065000212,-0.019142858,-0.062893202,-1.20753825,-1.819379399,1.150632577,1.40953176,-9.734357687,-10.37588291,-12.87520291,-9.240058311,-8.097327408,-8.083316895,-5.958837476,-3.63623415 -1443,L100A,0.008624509,-0.0121834,-0.000356801,-0.670952843,-1.874839901,0.023214347,0.054282935,-0.037033917,0.007229405,0.034483876,-0.058850676,0.001791359,-0.002504961,-0.350772929,-0.991132756,-1.884707541,-1.86497226,1.456328119,1.365293004,-10.33374989,-9.4850065,-11.48482115,-11.64229968,-9.321733658,-9.734888474,-7.605768038,-2.951748358 -1444,L100C,-0.006494503,0.003785441,-0.00299144,-0.131921006,-1.578448819,0.015544672,0.031295164,-0.044284169,-0.003974119,0.059990518,-0.052419637,-0.028802962,0.022820082,-0.068445598,-0.195396414,-1.618030786,-1.538866851,0.934034445,1.330489842,-12.82224128,-11.61815456,-14.45777967,-15.16076732,-12.28250729,-10.59199757,-8.759084584,-3.703297913 -1445,L100E,0.069085177,0.026311212,0.063420013,-1.264837643,-2.299156545,0.020310343,0.114810433,0.02335992,0.009706429,0.052536723,0.0000857,0.051831058,0.075008967,-1.054939917,-1.474735368,-2.41709392,-2.18121917,0.66682379,0.738463644,-13.46424802,-11.23469312,-15.10226397,-14.99543226,-14.53352421,-11.45532656,-7.976583911,-4.681008609 -1446,L100D,-0.000991636,-0.057543735,-0.949085307,-2.402394532,-2.838073156,0.04314573,0.05091213,-0.052895401,-0.044562732,-0.032957888,-0.082129582,-0.765119311,-1.133051303,-1.859991063,-2.944798001,-2.568932552,-3.107213759,2.247727338,1.036117611,-13.62008586,-12.22181487,-15.38080258,-15.4717882,-12.35701683,-12.66900681,-9.256658105,-5.710736052 -1447,L100G,0.04452576,-0.012661908,-0.056458048,-1.482686804,-2.556103373,0.010820774,0.069046912,0.020004608,0.017126442,0.005939836,-0.031263652,-0.033696927,-0.079219168,-1.372754138,-1.592619469,-2.257786886,-2.854419859,0.829764528,0.726722803,-14.38790148,-13.10093684,-15.54106105,-16.82932954,-13.88644078,-12.58173921,-8.463441861,-4.4412701 -1448,L100F,0.012780472,-0.099574358,-0.081196897,0.017743609,-0.800498928,0.077016204,0.023983859,0.001577085,-0.067379677,-0.107300274,-0.091848441,-0.130620939,-0.031772855,-0.014714405,0.050201623,-0.640290085,-0.960707771,1.089826752,1.526499346,-8.781433965,-8.611037048,-8.736151833,-10.0788875,-7.166269592,-9.314823845,-6.572888328,-2.741128581 -1449,L100I,-0.007413344,-0.025425415,-0.065945604,0.04125572,-0.058038304,-0.046753502,-0.016918523,0.002091835,-0.003705924,0.02447019,-0.07532102,-0.01078439,-0.121106818,0.076187446,0.006323994,-0.017825125,-0.098251483,1.298464299,2.633524663,-3.796006682,-3.470388252,-3.276826218,-4.63614193,-4.205289978,-3.391387032,-3.950540725,-0.984448878 -1450,L100H,0.120961928,0.001193637,0.015603395,-0.596797806,-2.30765856,-0.038398616,0.132564623,0.109359232,0.040551503,-0.017906398,0.020293671,-0.029786164,0.060992954,-0.462166114,-0.731429497,-1.748344011,-2.866973108,1.770083663,1.469609763,-15.25721549,-12.58586889,-16.86267957,-19.41557101,-13.68262695,-13.73933102,-8.320346233,-4.428723057 -1451,L100K,0.015045035,0.050939232,-0.032120966,-0.59514723,-2.008377529,0.058340918,0.02151788,0.00857219,-0.067167152,0.085794008,0.016084456,0.052602589,-0.11684452,-0.259753107,-0.930541353,-1.764574613,-2.252180445,1.232671325,1.350353263,-13.84331668,-11.27451962,-17.19906342,-16.03039008,-13.06815162,-11.64445865,-8.181461087,-1.560365973 -1452,L100M,0.081062246,0.003399156,0.035572193,0.059511076,-0.046431063,-0.082988235,0.088287968,0.073836523,-0.074185199,0.041089242,-0.03429093,0.076825435,-0.005681049,0.06555902,0.053463132,0.004581709,-0.097443834,1.180784266,2.76503108,-5.612350418,-4.590950951,-6.835494308,-5.636746521,-5.614126923,-5.384433388,-5.93507021,-2.229269104 -1453,L100N,-0.03520194,-0.040607703,0.002554084,-1.538654494,-2.650424377,-0.005670916,0.003322036,-0.073725915,-0.025327572,0.032771941,-0.113987346,0.03543657,-0.030328402,-1.227408551,-1.849900437,-2.209351312,-3.091497441,0.605937558,0.720605082,-13.98995523,-12.59193236,-16.51840735,-16.67777971,-12.98877168,-11.17288505,-8.905826304,-5.556639337 -1454,L100Q,-0.00752974,-0.031418546,-0.004820762,-0.07634366,-2.118330946,0.068156648,0.053867821,-0.068927301,-0.111356048,0.054957485,-0.117794576,0.0632825,-0.072924023,-0.007756643,-0.144930676,-1.563203935,-2.673457957,0.498500683,1.308308003,-13.31099151,-11.64330601,-15.79271571,-15.42940668,-12.17757915,-11.51195002,-8.012480048,-3.460561815 -1455,L100P,0.009922851,-0.017830736,-0.484691017,-1.666375229,-2.574295188,0.023910363,0.034491897,-0.014646196,-0.071032917,0.004670035,-0.040331506,-0.345200935,-0.624181099,-1.459967515,-1.872782942,-2.674058983,-2.474531393,1.576946984,0.86369468,-12.56784305,-11.57957814,-13.75393157,-14.41034171,-11.84157236,-11.25379146,-7.822430705,-3.874440405 -1456,L100S,-0.016146079,-0.043350732,-0.002183637,-0.963785208,-1.979998024,0.03002095,0.005519099,-0.037811257,-0.069093055,0.06019559,-0.146897053,0.016538737,-0.020906011,-0.706139745,-1.221430671,-1.764574613,-2.195421434,2.078888191,1.594958114,-11.97116391,-11.60446395,-13.41348696,-15.28490882,-10.10823294,-9.444726898,-8.289123435,-4.067252454 -1457,L100R,0.035183038,0.028796213,0.019032855,-0.900364816,-2.178643147,0.053522693,0.072583005,-0.002216929,0.039455133,0.04414355,0.013448876,0.01306036,0.02500535,-0.596014369,-1.204715262,-1.923829348,-2.433456945,1.805450711,1.432610967,-12.88631851,-10.7898325,-14.51293217,-15.33464972,-11.97701739,-11.81716077,-7.393167383,-1.323566 -1458,L100T,0.01287456,-0.019500061,-0.008604126,0.041854564,-1.821399928,0.016153499,0.027241134,-0.001492015,-0.058064477,0.016325445,-0.055325566,-0.021339982,0.004131731,0.024002413,0.059706714,-1.74340976,-1.899390096,0.653236191,1.306784194,-10.24344375,-9.864686562,-11.38535329,-11.49342517,-9.973880402,-8.499873314,-7.163056435,-3.654258309 -1459,L100W,0.039834702,0.193503736,0.023915759,-0.199697222,-1.185561117,-0.075500213,0.077120497,0.002548907,-0.143834194,0.089969949,0.297037522,-0.022402717,0.070234235,-0.125243398,-0.274151045,-0.885337409,-1.485784825,1.507249156,1.636807226,-12.96410663,-11.10182265,-14.53266254,-15.01579838,-11.34495219,-12.82529742,-8.537392603,-4.372547541 -1460,L100V,0.022807697,-0.025810865,-0.031260768,-0.001641051,-0.055273939,-0.009363071,0.005259839,0.040355554,0.018198766,-0.003786767,-0.047834962,-0.032706403,-0.029815132,0.022679814,-0.025961916,-0.025233372,-0.085314506,1.296077307,2.60688446,-5.027358707,-4.456010727,-4.798056648,-5.245660141,-5.714666939,-4.922399078,-4.534087918,-1.351412077 -1461,L100Y,0.02130023,-0.044975233,-0.046214999,-0.158632519,-1.521559049,-0.002148319,0.048840149,-0.00623969,0.023011649,-0.03769053,-0.052259936,-0.011717817,-0.080712181,-0.046248145,-0.271016892,-1.557535694,-1.485582404,0.746966791,1.321193804,-12.60114666,-10.51082557,-13.4054478,-14.79172868,-11.09430486,-13.20342639,-8.069938448,-2.732712442 -1462,V101A,0.008206899,-0.074177884,-0.025509105,0.000123777,-0.700294787,-0.114270741,-0.01549127,0.031905067,-0.026152135,-0.047745897,-0.10060987,-0.004642138,-0.046376072,0.006913988,-0.006666435,-0.523805793,-0.87678378,1.344793343,1.732996815,-3.880361235,-4.000896461,-3.777811852,-4.13847258,-3.681284386,-3.803340897,-4.249977216,-1.977798999 -1463,V101C,0.00140295,-0.054240445,-0.029033315,-0.03815164,-0.595665493,0.045219282,0.003997926,-0.001192026,-0.030713266,-0.009221036,-0.099259853,0.02776253,-0.085829159,-0.012394608,-0.063908672,-0.432543664,-0.758787321,0.976689077,1.573872006,-8.208125743,-7.445195602,-8.641171906,-9.20864167,-7.824709831,-7.920909706,-5.676097181,-4.648518448 -1464,V101E,0.01716608,-0.02887265,0.00331768,0.013008437,-0.743983116,-0.067678153,-0.006063003,0.040395163,-0.046835444,-0.019456258,-0.038289041,0.058245795,-0.051610436,0.05431867,-0.028301797,-0.695010265,-0.792955966,0.587891272,1.375472555,-3.985370969,-3.069192596,-4.284347839,-5.517246414,-2.866098198,-4.189969795,-3.935353416,-2.854220241 -1465,V101D,-0.085234134,-0.036065667,-0.065456291,-0.015518456,-0.211748794,-0.104100349,-0.095265502,-0.075202766,0.060365818,0.005628085,-0.077759419,0.014042132,-0.144954713,-0.02389062,-0.007146291,-0.186087269,-0.237410319,1.426412995,2.138902501,-4.014523843,-2.998678535,-3.525042107,-5.957768463,-2.969657921,-4.621472191,-2.768067491,-3.160112619 -1466,V101G,-0.082446243,-0.123052652,-0.103543162,-0.058004734,-1.239269328,-0.038792621,-0.069823237,-0.095069249,-0.048811616,-0.142117437,-0.103987866,-0.051330933,-0.155755391,-0.051400975,-0.064608493,-1.091866486,-1.38667217,0.97351283,1.388743526,-6.41122159,-6.194864738,-7.382337112,-6.356102562,-6.884453873,-5.238349663,-3.921357758,-3.41415185 -1467,V101F,-0.051049702,-0.084820709,-0.068893434,-0.015050727,-1.869255391,0.009158333,-0.049471927,-0.052627476,0.021181024,-0.086754618,-0.082886799,-0.045692248,-0.09209462,-0.027755664,-0.002345789,-1.627509609,-2.111001173,0.812313699,1.32068704,-9.260007652,-7.865620659,-10.16602711,-9.879875145,-9.158323143,-9.2301922,-6.143244927,-5.495342057 -1468,V101I,-0.003680317,-0.032331708,-0.045749995,-0.016762254,-0.101148046,-0.081834226,-0.020841701,0.013481067,0.009234178,0.014061253,-0.078724669,0.026961249,-0.118461238,0.014299131,-0.047823638,-0.061324348,-0.140971743,1.186960563,2.419344848,-2.131982387,-1.497711227,-2.015309097,-3.255734673,-2.22829332,-1.662863617,-1.404562806,-2.256641381 -1469,V101H,-0.142654277,-0.070281178,-0.160339964,-0.140443256,-1.336747924,-0.037576436,-0.062560803,-0.222747751,-0.032849754,-0.072748166,-0.06781419,-0.088290221,-0.232389707,-0.075882964,-0.205003548,-1.068414445,-1.605081403,1.012516162,1.399890844,-7.833984833,-6.200201767,-8.863086891,-9.964238686,-5.447379738,-8.695017082,-5.508236307,-3.538138236 -1470,V101K,-0.045799587,-0.050880935,-0.061683167,-0.026262724,-0.277032486,-0.087705241,-0.081031083,-0.01056809,0.03527576,-0.027970472,-0.073791398,0.037573103,-0.160939436,0.008216954,-0.060742401,-0.228022763,-0.326042209,1.04235952,1.808523932,-5.812260892,-3.593651321,-6.24624646,-7.171289268,-5.389449333,-6.660668076,-4.274398339,-3.218913762 -1471,V101M,-0.048310375,-0.014179108,-0.004076687,-0.005777791,-0.242102515,0.000534606,-0.106007802,0.009387052,0.028969499,-0.013066696,-0.015291519,0.0645793,-0.072732674,0.044297641,-0.055853223,-0.223513767,-0.260691263,1.435380181,2.134776638,-4.416560565,-3.282515663,-5.143993752,-4.74832563,-4.505488739,-4.402479042,-3.291048368,-3.342721078 -1472,V101L,0.007674565,-0.062413453,-0.030946065,-0.028630777,-0.080784456,0.15811939,-0.019943159,0.035292289,-0.01748611,-0.073043126,-0.051783779,-0.015315171,-0.046576958,-0.038212659,-0.019048895,-0.119567417,-0.042001495,1.427564573,2.373043227,-2.094922362,-0.936562508,-2.969531052,-2.891577209,-1.881332863,-1.795608177,-2.419421337,-1.12586454 -1473,V101N,-0.059574303,-0.053307408,-0.053331051,-0.033133682,-0.804123866,-0.00892416,-0.025155449,-0.093993157,0.013061947,-0.023901831,-0.082712985,0.023916871,-0.130578972,-0.023364056,-0.042903308,-0.688761315,-0.919486417,0.882893779,1.451681311,-6.851215872,-4.87930722,-7.029960434,-8.799150688,-5.910724159,-7.636936859,-5.325274756,-3.80443933 -1474,V101Q,0.028234629,-0.074500394,-0.064478207,-0.122584557,-0.253280102,-0.05782595,-0.003515759,0.059985016,-0.048126068,-0.046177599,-0.102823189,-0.040191058,-0.088765355,-0.112234703,-0.132934411,-0.21631756,-0.290242644,1.603270779,2.222565483,-3.804339897,-2.68290757,-4.656007332,-4.925435654,-2.599790192,-4.157558739,-3.383533512,-2.830214008 -1475,V101P,-0.044586013,-0.061496819,-0.903788175,-1.891763742,-2.538546594,-0.046694286,-0.040663834,-0.048508192,-0.004657149,-0.051278539,-0.071715098,-0.695284123,-1.112292226,-1.730669062,-2.052858422,-2.577126011,-2.499967177,2.231668402,1.088860772,-6.572604436,-5.912687088,-7.925654701,-8.041247398,-5.494071762,-5.489361229,-4.839128021,-4.393586076 -1476,V101S,0.025896471,-0.047804625,-0.047244324,0.002169952,-0.734571924,-0.124682453,-0.018641537,0.070434479,0.043303816,-0.043029919,-0.052579331,-0.031036242,-0.063452406,-0.034332089,0.038671992,-0.690441106,-0.778702741,1.017574141,1.482115366,-5.707502646,-5.347594399,-5.169382431,-5.959848465,-6.1121203,-5.948567635,-4.457939644,-2.300164485 -1477,V101R,-0.029726575,-0.071618527,-0.063180361,-0.047036554,-0.498956704,-0.097602212,-0.056275436,-0.003177714,0.002532095,-0.072453217,-0.070783837,-0.026240007,-0.100120714,-0.054944091,-0.039129016,-0.495151979,-0.502761429,1.366071089,1.752833536,-5.432205493,-3.78891935,-6.812360054,-5.793337418,-3.743504906,-7.022905739,-4.296788008,-2.98782462 -1478,V101T,0.019684723,-0.012713367,-0.018160094,0.007474944,-0.118362671,-0.110620274,-0.002052593,0.041422038,-0.018321086,0.01312904,-0.038555774,0.066667486,-0.102987674,0.003752994,0.011196893,-0.128770027,-0.107955315,1.250718248,2.135231092,-4.827128206,-4.22329908,-3.573408829,-5.426389748,-4.878798126,-6.033745247,-3.597625433,-1.59421207 -1479,V101W,-0.118609412,-0.085934709,-0.129582387,-0.272017541,-2.291497139,0.132537153,-0.177247836,-0.059970987,0.101158113,-0.073553161,-0.098316256,-0.076364138,-0.182800636,-0.15946779,-0.384567291,-1.996969896,-2.586024382,1.176680558,1.321391186,-9.296819786,-7.964083351,-9.725465446,-9.787296547,-8.687521454,-10.31973213,-6.320729173,-5.48555408 -1480,V101Y,-0.023634122,-0.052784914,-0.021404766,0.002228609,-1.502920358,-0.023810401,-0.051837696,0.004569452,-0.028127705,-0.031355481,-0.074214346,-0.015984964,-0.026824567,-0.011095422,0.01555264,-1.771385874,-1.234454842,0.653236191,1.306784194,-9.572959401,-8.212651512,-11.42275547,-10.31059773,-7.713855865,-10.20493642,-6.376426021,-2.666014004 -1481,E102A,0.009324818,-0.011267963,-0.040806359,-0.001681521,0.016406132,0.093191201,0.017112309,0.001537327,-0.057500062,0.015545413,-0.038081339,0.007226318,-0.088839036,-0.009789404,0.006426362,0.088845584,-0.05603332,1.139982465,2.831820233,-1.343915956,-1.815431198,-1.3435783,-1.120621513,-1.862148422,-0.577800346,-2.498388331,0.12264348 -1482,E102C,0.03817808,0.020783745,-0.009173916,-0.294042918,-1.752428509,0.075337212,0.026616461,0.049739698,-0.066984619,-0.043643462,0.085210952,-0.046044698,0.027696866,-0.217896912,-0.370188924,-1.515160298,-1.989696719,1.341388528,1.405567536,-8.232932544,-8.797414162,-8.187144608,-7.543496971,-9.597824142,-7.038782837,-8.841266829,-7.868517891 -1483,E102D,0.084501334,-0.037281977,-0.01120785,0.003255996,-0.002974238,-0.055364285,0.053865706,0.115136962,-0.073139913,-0.099188284,0.02462433,-0.037955762,0.015540062,-0.039662496,0.046174487,0.027913937,-0.033862413,1.132670201,2.661337655,-0.674036978,-0.819597687,-0.674686943,-0.331117676,-1.716814049,0.172031464,-2.208766519,0.354471828 -1484,E102G,0.040304391,-0.020944637,-0.044042417,-0.007946243,-0.29465882,-0.090591265,0.031969668,0.048639113,-0.04062282,-0.042781599,0.000892325,-0.025419334,-0.062665499,-0.034307755,0.01841527,-0.213905427,-0.375412213,1.320039096,2.004616634,-4.315171599,-4.054072456,-3.923491768,-3.124240349,-7.553096039,-2.920957382,-3.805849229,0.692637502 -1485,E102F,0.047593372,-0.031544983,-0.024743712,-0.00882471,-0.087691599,0.118680762,0.011223055,0.083963688,0.063358804,-0.123857767,0.060767802,-0.076738442,0.027251018,-0.03673505,0.01908563,-0.07633884,-0.099044357,1.277959855,2.292871582,-7.093479344,-10.14669139,-7.010332642,-5.680098984,-7.00747506,-5.622798645,-5.300078281,-2.251818605 -1486,E102I,0.008491857,-0.04983913,0.023612084,-0.022212045,-0.098005738,0.291178254,0.003391596,0.013592117,0.098993168,-0.097017765,-0.002660495,-0.00495163,0.052175798,0.010456719,-0.054880808,-0.049956986,-0.14605449,1.232510956,2.457426879,-6.386460905,-8.307892403,-4.518826889,-4.512192841,-8.962811745,-5.63058065,-5.655494227,-2.288066357 -1487,E102H,0.01640576,-0.044646386,-0.083456721,-0.095656738,-0.068771438,0.075979735,-0.010922684,0.043734204,0.155856864,-0.103943101,0.014650329,-0.067147861,-0.09976558,-0.114781173,-0.076532302,-0.018109408,-0.119433468,1.349850147,2.429634139,-5.48800166,-5.051740532,-5.630500641,-4.86459774,-7.052422623,-4.840746765,-5.093037183,-3.233006899 -1488,E102K,0.06217737,-0.013209647,0.051156691,0.02096043,-0.062874373,0.57346682,0.057277158,0.067077582,-0.154563648,-0.031005948,0.004586655,-0.073533302,0.175846683,-0.039458937,0.081379796,-0.04779888,-0.077949865,1.546473607,2.938183126,-2.890925082,-2.715477615,-3.055262314,-3.095536133,-2.945983826,-2.642365524,-2.753194389,-1.256679882 -1489,E102M,0.031540671,-0.04680941,-0.078978543,-0.013850513,-0.062337676,0.368950367,0.018357915,0.044723426,0.038115748,-0.068310857,-0.025307963,-0.067710183,-0.090246903,-0.023413062,-0.004287964,-0.007049118,-0.117626234,1.223079145,2.515572017,-7.317632324,-8.891729172,-6.44075914,-6.26672892,-8.594620201,-6.394324188,-5.684519994,-3.388936278 -1490,E102L,-0.006275741,-0.010432165,-0.057204765,-0.038738426,-0.06177225,0.182683471,-0.034371565,0.021820083,-0.038022214,-0.039957769,0.019093439,-0.03753098,-0.07687855,-0.034852693,-0.042624159,-0.009280985,-0.114263514,1.209166103,2.536844099,-6.510111388,-7.429902374,-5.696772003,-5.688899849,-8.347153587,-5.387829124,-5.64632106,-1.225266268 -1491,E102N,0.012213955,-0.045907116,-0.049959262,0.006167113,-0.086305347,0.069316667,-0.070637473,0.095065383,0.296111112,-0.048221802,-0.043592429,-0.018143727,-0.081774797,0.000398714,0.011935512,-0.015796712,-0.156813982,1.184187625,2.515322054,-3.314510609,-3.437925491,-3.17030925,-2.581079033,-4.781284988,-2.601954285,-4.727050118,-1.206964237 -1492,E102Q,0.02061284,-0.004829368,-0.063993284,-0.020900025,-0.045655708,0.145492132,-0.014632137,0.055857817,-0.059044065,-0.022341431,0.012682695,-0.056801164,-0.071185403,-0.06412864,0.02232859,0.029051498,-0.120362914,1.082345107,2.565519696,-4.386887163,-3.960969078,-4.304307701,-4.01247226,-5.473025574,-4.183661201,-5.527484835,-2.043886294 -1493,E102P,0.038249172,-0.002460804,-0.022889627,-0.019182979,0.007137683,0.092114996,0.012390265,0.064108078,-0.041275601,-0.043968409,0.039046801,-0.044942734,-0.000836519,-0.057885215,0.019519257,0.032059817,-0.017784452,1.258591366,2.702723941,-2.620635217,-2.963142006,-2.369987312,-2.960321091,-3.099378342,-1.710347336,-3.743732657,0.748206944 -1494,E102S,0.05995079,-0.005103225,-0.001061905,0.001762195,0.012132849,0.145389058,0.032424103,0.087477477,-0.035802712,-0.027116631,0.016910182,-0.01189591,0.009772101,-0.035596431,0.039120821,0.041468617,-0.017202919,1.083897781,2.677064204,-1.308189906,-0.650446152,-1.637133102,-1.280035049,-2.60889576,-0.364439468,-2.712106753,0.021227589 -1495,E102R,0.013658168,-0.003216132,-0.053470786,-0.048473594,-0.112260649,0.347115432,-0.010739465,0.0380558,-0.036089128,-0.041510326,0.035078062,-0.06530898,-0.041632591,-0.075193301,-0.021753886,-0.085959189,-0.138562108,1.426699217,2.364769258,-4.314601163,-4.751068985,-3.52405098,-4.108197594,-6.120448586,-3.06923967,-5.290723528,-1.508825172 -1496,E102T,0.018578095,-0.036185839,-0.050671618,-0.027174231,-0.019363092,0.101853035,-0.015841258,0.052997447,-0.003918902,-0.044475951,-0.027895727,-0.029847345,-0.071495891,-0.040464941,-0.01388352,0.04698381,-0.085709994,1.272442665,2.77972392,-0.568495905,-1.162286949,-0.500584045,0.070184097,-1.269374565,0.01958194,-1.745315367,-0.099689136 -1497,E102W,0.039110305,-0.040687855,-0.075823539,-0.0267243,-0.754648517,0.173497943,0.009531412,0.068689197,-0.058809471,-0.095104894,0.013729185,-0.059090141,-0.092556936,-0.102768496,0.049319897,-0.607386987,-0.901910046,1.08192449,1.581914154,-8.513880128,-10.29420113,-8.831783478,-7.270202133,-9.254826851,-6.918387054,-6.987322833,-4.608140957 -1498,E102V,0.0045454,-0.002425635,-0.0346032,-0.028692036,-0.013551254,0.152050241,-0.029428149,0.038518948,-0.037302743,-0.04292256,0.03807129,-0.025311912,-0.043894488,-0.046921207,-0.010462865,0.034172925,-0.061275432,1.201001598,2.673484086,-4.096636218,-5.643042847,-1.81495919,-2.92001326,-6.355567253,-3.749598541,-4.046628611,-1.160749028 -1499,E102Y,0.046666956,0.026181052,0.01925528,0.0632316,-0.043454595,0.119325934,-0.007183132,0.100517044,0.01897743,0.017599386,0.034762718,0.01061948,0.02789108,0.023395332,0.103067868,0.032808621,-0.119717811,1.144371154,2.808825171,-6.80886499,-8.305018318,-6.945234612,-5.400565323,-7.673615402,-5.719891296,-5.347930821,-2.396955138 -1500,Y103A,-0.03559329,-0.048070527,-0.01945544,-0.051418075,-1.550650111,-0.070933509,-0.099982864,0.028796285,-0.082899299,-0.027657957,-0.068483097,-0.01684759,-0.02206329,-0.007364113,-0.095472037,-1.65569067,-1.445609552,0.849189535,1.323058377,-10.58668431,-8.32005513,-11.64706407,-10.15951344,-10.90376273,-11.90302619,-6.153452581,-2.214940636 -1501,Y103C,-0.031449683,-0.004988079,-0.013592198,-0.243704384,-1.854637148,0.012208953,-0.066108271,0.003208906,-0.108491886,0.016853729,-0.026829887,-0.007170897,-0.020013498,-0.24748156,-0.239927207,-1.733519566,-1.975754729,0.549186742,1.302912209,-11.38701479,-11.72793298,-12.8054844,-10.54441958,-12.32794434,-9.529292671,-8.146801337,-3.991393758 -1502,Y103E,-0.037127773,-0.054230348,-0.104296497,-1.571789792,-2.177651822,-0.034278309,-0.075840503,0.001584957,0.144534293,-0.060238366,-0.048222329,-0.043725809,-0.164867184,-1.354360387,-1.789219196,-2.193434828,-2.161868815,0.69862739,0.714720758,-11.80405332,-9.769531105,-14.57684316,-10.9264632,-12.14618439,-11.60124477,-7.1179922,-3.863271172 -1503,Y103D,-0.048571813,-0.051599948,-0.029027702,-1.193106894,-2.22642002,-0.064897566,-0.071144424,-0.025999202,-0.037141808,-0.089154429,-0.014045466,-0.034058468,-0.023996935,-0.981147274,-1.405066514,-1.934761217,-2.518078822,2.334798968,1.642784759,-10.99473507,-9.986297546,-12.34714725,-9.618599854,-10.80920096,-12.21242976,-6.502266979,-2.806886266 -1504,Y103G,-0.006398069,-0.033022068,-0.011694527,-0.002136913,-1.545910543,-0.071113114,-0.05603484,0.043238702,-0.105683937,-0.054181907,-0.011862229,-0.017628366,-0.005760688,-0.000602284,-0.003671541,-1.48655636,-1.605264726,0.691278813,1.320506574,-9.984625732,-7.996547371,-12.79886829,-7.766943932,-11.00894549,-10.35182359,-6.055454284,0.254467632 -1505,Y103F,-0.045050736,-0.041058297,-0.044771949,-0.034330937,-0.238752093,-0.022781128,-0.06694679,-0.023154681,-0.074633618,-0.056662684,-0.02545391,-0.050134098,-0.039409799,-0.07701,0.008348126,-0.244799734,-0.232704452,1.199372656,1.934319402,-5.768057954,-6.499505821,-6.101388039,-5.32119944,-6.51408326,-4.404113213,-6.009323404,-3.106451295 -1506,Y103I,-0.147854871,-0.09985103,-0.068676027,-0.764696548,-1.635721029,-0.006047783,-0.178659375,-0.117050366,0.018483406,-0.097505061,-0.102196999,-0.049491338,-0.087860716,-0.493271355,-1.036121741,-2.005761697,-1.265680361,1.691139752,1.386271377,-11.30654185,-8.648484047,-12.92415092,-11.10504298,-11.55747438,-12.29755692,-7.217696664,-3.521978162 -1507,Y103H,-0.016535564,-0.00847579,-0.016529294,0.01321681,-0.782617213,-0.011871137,-0.017445498,-0.01562563,0.056904851,-0.0434239,0.02647232,-0.039347923,0.006289336,0.010275873,0.016157747,-0.67372613,-0.891508295,0.613258414,1.381434036,-3.808133841,-3.47374173,-5.321738358,-3.615427513,-3.204600006,-3.425161598,-4.120502916,-0.90385354 -1508,Y103K,-0.069037223,-0.113006186,-0.553997919,-1.871682074,-2.536416425,-0.018804023,-0.127481271,-0.010593174,-0.077604858,-0.117575044,-0.108437328,-0.52075424,-0.587241597,-1.558368308,-2.18499584,-2.73703614,-2.33579671,1.954938064,0.988051508,-11.28729712,-10.58492824,-12.92426598,-10.82130459,-11.63867317,-10.4673136,-8.318440213,-5.258716045 -1509,Y103M,-0.005309504,-0.023037357,0.024612126,0.009628693,-1.746080843,-0.082411258,-0.024730126,0.014111118,0.06069784,-0.005694071,-0.040380643,0.008437576,0.040786675,0.015908195,0.003349191,-1.427160737,-2.065000948,0.562446154,1.317175385,-12.20713058,-10.73150129,-12.95494767,-11.89488287,-12.90501578,-12.54930528,-8.724300107,-5.714755152 -1510,Y103L,-0.087192536,-0.06105568,-0.031958366,-0.795664329,-1.681825516,-0.027080824,-0.118948573,-0.055436499,-0.015239967,-0.068464047,-0.053647313,-0.024847423,-0.039069309,-0.580260711,-1.011067946,-1.858199871,-1.505451161,1.860797327,1.472915086,-10.40651469,-9.098682419,-10.59733482,-10.39720757,-10.96252936,-10.97681927,-7.661885488,-4.341591415 -1511,Y103N,-0.086452977,-0.036985253,-0.036149186,-0.010693496,-1.246747,-0.024792718,-0.123005756,-0.049900198,0.008723568,-0.037613603,-0.036356902,-0.024810927,-0.047487445,0.056794352,-0.078181343,-1.214824002,-1.278669997,0.747634137,1.342288318,-7.378222765,-6.824054535,-9.145194984,-5.81346492,-6.776937836,-8.331461548,-4.472886572,-1.503383158 -1512,Y103Q,-0.043592799,-0.045826657,-0.03952644,-0.354801926,-1.936924464,-0.03371773,-0.075265659,-0.011919938,-0.027274085,-0.045574512,-0.046078801,-0.015686443,-0.063366436,-0.21147502,-0.498128832,-1.96167779,-1.912171137,1.20062038,1.324761023,-11.90304338,-11.52050692,-13.53723603,-11.38730995,-11.38933994,-11.68082406,-9.067966532,-6.075925448 -1513,Y103P,-0.004184865,-0.061144263,-0.001596155,-0.029937283,-1.125442206,-0.057069363,-0.037174275,0.028804546,-0.068514641,-0.05106669,-0.071221836,0.015367712,-0.018560021,-0.034395245,-0.025479321,-0.966082843,-1.284801569,0.707424903,1.359969576,-10.83940805,-7.163017395,-12.33770146,-10.80043841,-11.78328873,-12.11259427,-6.30387546,-1.781710091 -1514,Y103S,-0.058107825,-0.076590034,-0.034134028,-0.039833439,-1.620639579,-0.032681068,-0.09996706,-0.016248589,0.035581861,-0.062493145,-0.090686922,-0.035083324,-0.033184731,-0.011338403,-0.068328474,-1.455326918,-1.785952239,0.724735601,1.324854029,-9.63598418,-8.463795853,-10.24886179,-8.527913765,-10.41395418,-10.52539531,-6.319579689,-2.09117894 -1515,Y103R,-0.02028246,-0.043373997,-0.070106194,-1.464283561,-1.838422416,-0.000104532,-0.077301829,0.036736909,0.00109809,-0.031883118,-0.054864875,0.000350808,-0.140563195,-1.184431568,-1.744135553,-1.989408132,-1.687436699,2.458354126,1.657256172,-10.73542044,-11.03280269,-12.70386889,-10.13294577,-10.26699504,-9.54048983,-7.799677558,-3.983543603 -1516,Y103T,-0.010662202,-0.034830394,0.027119002,-0.119636277,-1.557550548,0.012957308,-0.049716583,0.028392179,0.103219487,-0.031605951,-0.038054836,0.064439774,-0.01020177,-0.051320695,-0.187951858,-1.579323203,-1.535777893,0.752933446,1.320191275,-10.97757031,-8.37180751,-12.24469241,-10.87271519,-11.45687282,-11.9417636,-6.223895613,-2.657740428 -1517,Y103W,0.026650333,-0.013341438,-0.015070132,0.002494321,0.054448019,0.217568471,-0.000215424,0.053516089,-0.148062535,-0.045086637,0.018403762,0.005861089,-0.036001353,-0.054417487,0.059406128,-0.017988184,0.126884222,1.335850987,2.63641595,-2.780876294,-2.692244591,-2.950314125,-2.190871437,-3.044257339,-3.026693977,-3.139830358,-1.06000399 -1518,Y103V,-0.044995515,-0.029783702,-0.043812507,-0.06333829,-1.551314318,-0.055253764,-0.094090319,0.004099289,-0.005829544,-0.024153359,-0.035414045,-0.039152383,-0.048472631,-0.014757913,-0.111918667,-1.576667665,-1.525960971,0.729236708,1.320133166,-10.54808046,-7.623221611,-12.24046948,-10.05284627,-10.56325972,-12.2606052,-6.430711591,-3.203959217 -1519,S104A,0.035921052,0.018118762,0.017096871,-0.014351967,-0.593591064,0.068802933,0.027193207,0.044648896,,0.000480532,0.035756992,0.019745832,0.01444791,-0.052625741,0.023921808,-0.419099723,-0.768082404,1.313633597,1.775772646,-4.270753961,-4.417247551,-3.207795624,-2.497953743,-6.382184814,-4.848588074,-4.321525992,-1.355635287 -1520,S104C,0.035432832,-0.015412063,-0.0197801,-0.098731414,-1.841876679,0.0340079,0.03818072,0.032684944,,-0.003788885,-0.027035241,-0.00000594,-0.039554259,-0.045515719,-0.151947108,-1.819031444,-1.864721913,0.80679212,1.310245976,-10.84921473,-14.95272893,-10.73463311,-8.579851265,-11.2325713,-8.74628907,-9.480809609,-4.659014079 -1521,S104E,-0.027544314,-0.409092289,-1.571020499,-2.233270979,-2.979643612,0.041909209,-0.030372099,-0.024716528,,-0.314545848,-0.50363873,-1.528659892,-1.613381105,-2.09224261,-2.374299347,-2.555991576,-3.403295647,2.886115032,1.184170041,-10.75390518,-12.96542772,-9.28160685,-9.463875977,-11.23250611,-10.82610926,-8.530517577,-3.949012306 -1522,S104D,0.158830124,-0.081482351,-0.389089631,-1.784036024,-2.486833569,0.029174325,0.182312962,0.135347286,,-0.020651869,-0.142312833,-0.231014426,-0.547164836,-1.545955218,-2.022116829,-2.524613999,-2.449053138,1.305800654,0.774063955,-11.26543315,-15.55046043,-10.29189278,-9.129799538,-12.32193037,-9.033082634,-8.457585883,-3.822061935 -1523,S104G,-0.006099387,0.001299559,0.023508868,-0.026190725,-1.652025149,0.059986738,-0.013330345,0.001131572,,0.028201469,-0.025602352,0.021306734,0.025711001,0.006218158,-0.058599607,-1.621801901,-1.682248397,0.464646141,1.304798765,-9.557354655,-12.44395766,-9.156423271,-8.626318481,-9.400219627,-8.159854233,-8.079238568,-2.235680439 -1524,S104F,-0.185633909,-0.199477848,-0.503831788,-1.773839444,-2.326121992,0.031715686,-0.169869556,-0.201398262,,0.002994447,-0.401950143,-0.159468745,-0.848194831,-1.525562059,-2.022116829,-2.203190845,-2.449053138,1.024732693,0.736181397,-12.64700634,-17.74628269,-13.21569376,-10.16850558,-11.77845152,-10.32609816,-8.277692576,-4.703870248 -1525,S104I,-0.047671754,-0.022634931,-0.964136742,-1.57694742,-1.89066934,-0.027957764,-0.057447377,-0.03789613,,0.075853672,-0.121123534,-0.816837218,-1.111436266,-1.608899265,-1.544995574,-1.809406796,-1.971931883,4.289146126,3.162138117,-13.4180276,-18.20587504,-14.84675288,-10.45207081,-11.6412735,-11.94416579,-9.300101527,-4.338774572 -1526,S104H,0.035223129,0.03480024,-0.112921474,-0.061958087,-1.905650951,-0.001791635,-0.080928473,0.151374731,,0.065785277,0.003815203,-0.24474045,0.018897502,-0.191704457,0.067788283,-1.839370019,-1.971931883,1.253838219,1.342705562,-12.21860896,-16.61524598,-11.15589542,-9.581099411,-11.61285402,-12.12794998,-9.616698566,-5.833198987 -1527,S104K,-0.04281585,-0.008242986,-0.454519614,-1.8191689,-2.464994769,0.046201794,-0.042400784,-0.043230915,,-0.005719175,-0.010766797,-0.280826816,-0.628212412,-1.465976369,-2.172361431,-2.745665146,-2.184324391,1.430574311,0.818752413,-12.17016467,-15.70732791,-9.583916588,-10.33060951,-12.29037216,-12.93859717,-10.65068302,-6.950523036 -1528,S104M,-0.018705375,0.019315543,-0.366394787,-1.652204748,-2.537879956,0.012366938,-0.019045202,-0.018365547,,0.026327772,0.012303313,-0.208517591,-0.524271983,-1.452631598,-1.851777898,-2.524044432,-2.551715479,1.209853782,0.769210384,-11.50950628,-15.27987972,-11.00421262,-9.434919487,-9.685558571,-12.14296103,-8.528150822,-5.104725364 -1529,S104L,-0.063361596,-0.86970304,-1.760762665,-2.220868606,-3.01316915,0.04296991,-0.063816164,-0.062907027,,-0.788318249,-0.95108783,-1.766019929,-1.755505401,-2.162495872,-2.279241339,-2.683338554,-3.342999745,3.157004253,1.15204559,-13.86177729,-18.65491854,-13.40665779,-12.31385849,-12.47566051,-12.45779109,-10.0766001,-6.315680945 -1530,S104N,-0.400913294,-0.036649293,-0.430663347,-0.335987351,-1.206680947,0.244394077,-0.512292237,-0.289534351,,-0.107077012,0.033778426,-0.573799169,-0.287527525,0.350142128,-1.022116829,-0.964308756,-1.449053138,0.307526788,1.321758068,-8.960142859,-13.09340082,-7.833773323,-6.174748207,-9.271837448,-8.426954498,-7.440023519,-3.824945501 -1531,S104Q,-0.033022956,0.000869751,-1.187447634,-2.158699108,-3.111797828,0.061076493,-0.01094754,-0.055098372,,0.024965585,-0.023226083,-1.101259813,-1.273635454,-1.832052203,-2.485346012,-3.311313335,-2.912282321,2.331760899,1.008100322,-10.2783317,-12.94771544,-7.769069839,-9.451548195,-9.524731232,-11.69859379,-8.712483701,-3.111747524 -1532,S104P,0.003832419,0.007738152,-1.156524794,-1.792250502,-2.474880172,0.02312021,0.013706551,-0.006041714,,0.020601762,-0.005125458,-1.073486252,-1.239563335,-1.766163667,-1.818337336,-2.451761382,-2.497998961,2.781978492,1.419641957,-10.82437539,-13.19598366,-10.20748555,-9.743901367,-11.35951141,-9.614994965,-8.36726091,-3.390519255 -1533,S104R,0.002650054,0.002274929,0.015895246,-1.487662208,-2.231699902,0.044020401,0.002883609,0.002416498,,0.028431729,-0.023881871,0.065062766,-0.033272274,-1.304615271,-1.670709145,-2.240815613,-2.22258419,0.869032308,0.737209522,-13.51099261,-16.97633954,-12.99467189,-11.29788361,-11.99122461,-14.2948434,-9.662088652,-6.054136587 -1534,S104T,-0.062068206,0.004185731,-0.012210634,-0.08759826,-1.723047291,0.064780043,-0.063639215,-0.060497196,,0.069014247,-0.060642786,0.016403975,-0.040825242,0.008462064,-0.183658583,-1.678282682,-1.7678119,0.583197104,1.306520317,-7.192254016,-10.0346138,-6.175500626,-4.880551376,-7.205511215,-7.665093063,-7.429014361,-1.908054045 -1535,S104W,0.02055038,-0.273629117,-1.45511843,-2.01250698,-2.463579428,0.044775612,0.022482069,0.018618691,,-0.222369467,-0.324888766,-1.536010609,-1.374226251,-2.053371598,-1.971642362,-2.679847861,-2.247310995,2.689127978,1.051204027,-15.0361096,-20.2697284,-15.45347575,-13.09120722,-13.43962217,-12.92651444,-9.694247609,-4.433458458 -1536,S104V,-0.023832545,0.011478471,0.038511949,-1.476238065,-2.203338277,0.042430237,-0.011585764,-0.036079326,,0.013594938,0.009362003,0.063768818,0.01325508,-1.24213729,-1.710338839,-2.372063747,-2.034612806,0.329774976,0.701162323,-13.03162991,-16.17375417,-14.94351566,-10.42150915,-11.68589626,-11.93347433,-8.990094367,-4.895315078 -1537,S104Y,-0.081882709,0.0079623,-0.165982911,-1.477763593,-2.140970515,-0.020740685,-0.035170982,-0.128594436,,0.158237432,-0.142312833,-0.07440152,-0.257564302,-1.167493562,-1.788033623,-2.066971098,-2.214969932,2.349526989,1.566459926,-14.07012977,-18.81313107,-15.26193134,-10.65555508,-12.76551349,-12.85451786,-9.184094847,-5.486132172 -1538,P105A,-0.01793208,0.008901083,-0.040817483,-0.018949929,-1.617908697,0.021493397,-0.029878114,-0.005986046,0.000859887,-0.010356597,0.028158763,-0.06274459,-0.018890375,-0.011694649,-0.026205209,-1.792601219,-1.443216175,0.653236191,1.306784194,-8.183916423,-8.63088575,-9.11003083,-10.44609914,-8.430067253,-4.302499138,-5.997965991,-3.330149169 -1539,P105C,-0.003247222,-0.027213308,-0.156932129,-1.693777268,-2.263977654,0.066878325,0.027371267,-0.03386571,0.043894519,-0.031578237,-0.022848379,-0.089038675,-0.224825582,-1.517709711,-1.869844825,-2.855021585,-1.672933722,0.856676489,0.714717859,-14.88022422,-14.70212283,-14.73780418,-17.87968893,-14.76103816,-12.320467,-10.61968155,-9.88449642 -1540,P105E,-0.004942236,-0.050056476,-0.009415334,-0.036943107,-1.507607725,0.030061054,0.019804276,-0.029688748,0.064515055,-0.096569729,-0.003543223,-0.006279066,-0.012551601,-0.001497794,-0.072388419,-1.583435632,-1.431779817,0.606928577,1.312592777,-10.54013443,-10.52849612,-11.07244686,-13.268897,-10.28899707,-7.541835121,-7.016667927,-3.967445298 -1541,P105D,-0.048215585,0.07212915,-0.034812273,-0.862645904,-2.270477617,0.050233417,-0.011999425,-0.084431744,0.010327172,0.014818333,0.129439966,-0.069674146,0.0000496,-0.49226908,-1.233022727,-1.816868989,-2.724086244,1.768289681,1.463445281,-10.89308444,-11.15907339,-11.16458569,-13.01095358,-11.46224634,-7.668563187,-6.594177009,-3.079261978 -1542,P105G,0.008789975,0.010468704,-0.026467088,-0.425160692,-1.889083431,0.022891033,0.013724922,0.003855028,0.02270522,-0.006954765,0.027892173,-0.007628245,-0.04530593,-0.237995142,-0.612326241,-1.671080958,-2.107085903,1.313787267,1.371444918,-12.00755628,-12.47442097,-12.92191518,-15.30946496,-11.75772208,-7.574258202,-6.851037865,-0.630004765 -1543,P105F,-0.015090107,-0.027415165,0.023680786,-0.095615566,-2.027326348,0.025645585,0.002295461,-0.032475674,-0.043255656,-0.038697978,-0.016132351,0.032162753,0.015198818,-0.039661467,-0.151569665,-1.884984809,-2.169667887,0.831809594,1.307575097,-14.26118269,-13.59833581,-13.9781762,-17.97867885,-14.02339073,-11.72733187,-8.565743591,-6.298960888 -1544,P105I,-0.008752117,-0.012170382,-0.001040544,-0.034353356,-1.902309225,-0.008400742,0.00365764,-0.021161873,0.08168308,-0.088631033,0.06429027,0.019534354,-0.021615442,0.003259243,-0.071965954,-1.38472072,-2.419897729,0.768160347,1.3320777,-12.55220648,-12.70648557,-12.95246433,-16.00149257,-11.62581812,-9.474771797,-7.561118543,-4.414047246 -1545,P105H,-0.034821038,-0.063627124,-0.08286858,-0.058331701,-1.607758802,0.060519002,-0.014137245,-0.055504831,-0.078896013,-0.068193696,-0.059060551,-0.100081148,-0.065656012,-0.032536578,-0.084126823,-1.559954537,-1.655563066,0.848508299,1.327273592,-13.24771158,-13.52739177,-13.37306887,-15.76852309,-13.58653336,-9.983040802,-9.508189892,-7.090362469 -1546,P105K,0.040550579,0.00962138,-0.021786681,0.037860859,-1.447940296,0.045619462,0.0744963,0.006604857,0.155469294,-0.046635425,0.065878185,-0.013858568,-0.029714794,0.024146874,0.051574844,-1.662616879,-1.233263712,0.77572445,1.316325833,-10.23545316,-9.995317497,-10.48635027,-13.57657024,-9.324647858,-7.794379921,-6.650368513,-4.325334746 -1547,P105M,0.122141858,0.049449026,0.030785725,0.022184932,-1.962940407,0.040343133,0.155564595,0.088719121,0.044770997,-0.067716555,0.166614606,-0.032457401,0.09402885,-0.06282062,0.107190484,-1.589625207,-2.336255606,0.910124828,1.331150371,-13.82033204,-13.43462017,-13.77744794,-17.26417176,-13.09853311,-11.52688721,-9.179539673,-6.514061512 -1548,P105L,-0.000146894,0.024546652,0.002379128,0.013450585,-1.565477837,-0.001078468,0.004017436,-0.004311223,0.127936624,-0.027172626,0.07626593,-0.018925075,0.02368333,0.018861468,0.008039702,-1.476891869,-1.654063804,0.5972855,1.318263149,-11.96882571,-12.10523785,-11.78603197,-15.72969044,-10.91333083,-9.309837486,-7.408650284,-4.587375 -1549,P105N,-0.083502704,-0.015762916,-0.040035207,-0.22099803,-1.957567679,0.035630603,-0.053848966,-0.113156441,-0.178729064,-0.019346431,-0.0121794,-0.023561581,-0.056508832,-0.128328704,-0.313667355,-1.823522141,-2.091613217,0.969145828,1.320385198,-12.71966361,-12.73664458,-13.02183746,-15.66556982,-11.96531635,-10.20894983,-7.638092331,-5.395338588 -1550,P105Q,-0.034140925,-0.031030927,-0.04710361,-0.026478542,-1.620682791,0.063970795,0.028791631,-0.09707348,0.100166486,-0.024903144,-0.03715871,-0.033331187,-0.060876033,0.014467916,-0.067425,-1.613889733,-1.627475848,0.650401536,1.312397861,-9.577311671,-9.445240051,-9.778481895,-12.07261974,-9.866071953,-6.724144714,-6.588568178,-4.46282686 -1551,P105S,-0.040579613,-0.025237115,-0.033118125,-0.06258959,-1.694489614,0.024509592,-0.040606891,-0.040552335,0.011467552,-0.000173989,-0.050300241,-0.019973372,-0.046262877,-0.024961666,-0.100217513,-1.698921395,-1.690057832,0.831963219,1.318474828,-9.712549828,-9.962574844,-9.112677452,-12.19323353,-9.532037682,-7.762225632,-6.640053631,-3.651936122 -1552,P105R,0.045418584,0.01942966,0.016155349,-0.044201782,-1.671099709,0.039525246,0.068929411,0.021907756,-0.048650688,-0.047185311,0.08604463,-0.045853353,0.07816405,-0.050417022,-0.037986541,-1.681403824,-1.660795593,0.820780722,1.318541315,-10.10178597,-9.360484497,-10.90127403,-13.17317694,-10.43359133,-6.640403046,-7.351476984,-4.606463974 -1553,P105T,0.014060598,0.038445465,0.061955485,0.03068217,-1.455280832,0.056494915,0.012057019,0.016064177,0.038217387,-0.023514036,0.100404965,0.05708936,0.06682161,0.070491659,-0.009127319,-1.718134206,-1.192427458,0.581978988,1.304089222,-10.24096958,-10.31091234,-9.775470108,-13.49628687,-10.07843818,-7.543740417,-7.475070943,-2.960931699 -1554,P105W,0.032360781,-0.055141448,0.02921437,-0.731199387,-2.167596652,0.04794837,0.052428751,0.012292811,-0.011873291,-0.029638052,-0.080644843,0.003866653,0.054562086,-0.418039077,-1.044359696,-2.135562193,-2.199631111,1.657516703,1.351194572,-13.63342761,-13.10945093,-13.4213783,-16.37908466,-14.3500128,-10.90721134,-8.196340755,-5.569952545 -1555,P105V,-0.03579981,0.006636147,0.001437604,0.014043222,-1.432323505,0.041421935,-0.046972918,-0.024626701,0.046324825,-0.028337318,0.041609611,0.012585422,-0.009710215,0.001405051,0.026681393,-1.365870046,-1.498776963,0.599050698,1.321589945,-9.777717067,-10.26856075,-10.84065807,-13.58177478,-9.254183716,-4.94340802,-5.993720357,-3.790407145 -1556,P105Y,0.031035067,0.001404172,0.023190147,-0.134138557,-1.396863702,0.012416606,0.064431481,-0.002361348,-0.121560425,-0.038315298,0.041123641,0.007291892,0.039088402,-0.086274464,-0.18200265,-1.666624387,-1.127103017,0.849128068,1.32312655,-15.22312528,-14.38848096,-15.70768102,-18.72192557,-15.12502209,-12.17251678,-9.505755045,-7.03838871 -1557,V106A,0.040560795,0.189789778,0.052723104,0.122016807,-0.238328783,0.014438517,0.040968802,0.040152788,0.057991947,0.183870647,0.195708908,0.09020624,0.015239967,0.140931052,0.103102562,-0.122624184,-0.354033381,1.101621924,2.144464447,-5.701955238,-7.02722979,-4.338239243,-5.603826057,-6.840277832,-4.70020327,-5.424723595,-2.450906467 -1558,V106C,0.095390719,0.185613481,0.066945423,0.183160664,-0.574227852,0.00959463,0.104850741,0.085930697,-0.025554104,0.161253626,0.209973336,0.055599134,0.078291712,0.154393291,0.211928036,-0.291523585,-0.856932118,0.576778308,1.495597345,-11.4135125,-12.19720108,-11.04635215,-11.60421555,-11.82806252,-10.39173122,-9.17493518,-6.285610929 -1559,V106E,-0.045490608,0.078293317,-0.013876799,0.154010643,-0.040876561,0.069304225,-0.049999017,-0.040982199,0.192690521,0.096855484,0.05973115,0.001738438,-0.029492035,0.195882644,0.112138642,0.055850389,-0.13760351,1.118471852,2.953325769,-7.372525443,-8.426553795,-4.822429672,-9.183023087,-8.542620766,-5.887999893,-5.094661904,-2.784845348 -1560,V106D,0.018907755,0.140182814,0.07019709,0.119724282,-1.664693309,-0.011591976,-0.01952214,0.05733765,0.114896798,0.192935816,0.087429812,0.013788284,0.126605896,0.134698574,0.10474999,-0.665004039,-2.664382579,0.489439367,1.363883,-10.54778447,-11.78373557,-7.638732864,-12.20328477,-11.33802912,-9.775140007,-8.058163799,-4.456255854 -1561,V106G,0.037119413,0.17474641,0.054450666,0.11300327,-1.515415773,0.014906618,-0.024547192,0.098786018,0.086868075,0.195341885,0.154150935,0.073099206,0.035802125,0.19328009,0.032726449,-1.438999633,-1.591831912,0.328642421,1.306471454,-8.318537059,-10.59705386,-5.633266159,-8.947756859,-8.463771027,-7.950837395,-6.675999319,-2.536237553 -1562,V106F,0.053303364,0.101230158,0.032783343,0.078542269,-1.138470781,-0.007803182,0.024480623,0.082126105,0.054096903,0.164477221,0.037983094,0.057388574,0.008178112,0.14903748,0.008047057,-0.878593317,-1.398348244,0.356557736,1.331731173,-7.57816237,-9.437637642,-7.923191467,-7.336012993,-7.450210274,-5.743759476,-6.735900841,-2.269551622 -1563,V106I,-0.038204822,0.085120143,0.036216752,0.092675555,0.001953832,-0.006124785,-0.098433889,0.022024246,0.04026318,0.099569834,0.070670452,0.032208235,0.040225269,0.174314049,0.01103706,0.082596406,-0.078688742,1.069397567,2.918971567,-1.928670465,-2.01879039,-1.325958763,-2.587385971,-1.627889198,-2.083328003,-3.036344123,-0.32733436 -1564,V106H,0.05111147,0.166401177,0.060213377,0.101255763,-0.99464539,0.049266485,0.019486581,0.082736359,0.048121193,0.146213575,0.186588778,0.007686298,0.112740455,0.117884753,0.084626772,-0.818076881,-1.171213898,0.542891475,1.353302695,-11.70872025,-12.9881496,-10.76695895,-12.95914153,-11.91350249,-9.915848671,-8.589171902,-5.38961001 -1565,V106K,-0.022416564,0.068244584,0.013801155,0.03255497,-1.285721958,-0.043217035,-0.121342751,0.076509623,0.023229841,0.095368682,0.041120486,0.037916448,-0.010314138,0.044573633,0.020536306,-0.988820006,-1.58262391,0.538657146,1.340835155,-10.03726227,-11.63066222,-8.182264084,-10.59329633,-10.58338097,-9.196707748,-7.425147137,-4.480806335 -1566,V106M,0.018275968,0.154644426,0.077251632,0.151870635,-0.066307304,0.002670331,0.000716339,0.035835596,0.076475353,0.138574339,0.170714513,0.063570379,0.090932885,0.173632552,0.130108718,-0.018783229,-0.113831378,1.113349719,2.638047589,-6.058070641,-6.517654953,-4.64036293,-6.356912933,-6.285455025,-6.489967361,-6.449590132,-2.122691734 -1567,V106L,0.06579748,0.120793762,0.054859487,0.109243264,-0.040586891,-0.022521454,0.024085374,0.107509586,0.078859666,0.130599768,0.110987755,0.026873334,0.08284564,0.142274404,0.076212124,0.011156991,-0.092330772,1.212728392,2.822566822,-4.591312445,-4.857283875,-4.498529449,-5.494381393,-4.183022606,-3.923344902,-4.260422238,-1.00123857 -1568,V106N,0.092335189,0.075597901,-0.002360615,0.15467567,-1.48746731,0.001060436,0.014133483,0.170536895,0.15241316,0.111694847,0.039500955,-0.036228808,0.031507579,0.111954252,0.197397087,-1.35644212,-1.6184925,0.620200026,1.32363291,-11.01460307,-12.41450238,-10.39368602,-11.37867662,-10.79963863,-10.0865117,-7.946479099,-4.270069712 -1569,V106Q,0.035560325,0.148246733,0.060772218,0.108465892,-0.356222844,-0.006471353,0.022079391,0.049041258,0.191679357,0.12427853,0.172214935,0.054275468,0.067268967,0.080890409,0.136041375,-0.144747455,-0.567698232,1.321153482,2.238630195,-9.838776402,-10.8736351,-8.337720718,-11.14127032,-9.958999893,-8.882255974,-7.390567424,-4.761639502 -1570,V106P,0.022797027,-0.190781916,-1.461804161,-1.907458094,-2.620729962,-0.002278002,0.008832164,0.03676189,-0.01570408,-0.064708046,-0.316855785,-1.429029177,-1.494579144,-1.69198461,-2.122931577,-2.317878725,-2.923581198,3.660230465,2.15179342,-11.15417601,-12.37912146,-9.915035973,-10.79244738,-12.06138328,-10.62289198,-8.573551377,-5.478402787 -1571,V106S,-0.034340377,0.108590195,0.010243626,0.083424601,-0.661677651,0.022091406,-0.075797896,0.007117143,0.066721778,0.127936661,0.089243728,0.018683155,0.001804096,0.121564853,0.045284349,-0.446419121,-0.87693618,0.571257879,1.419403244,-8.62546194,-9.891206688,-7.901045303,-7.785063843,-9.732408859,-7.817585007,-7.158087085,-2.683060737 -1572,V106R,0.086768315,0.127891355,0.030298518,0.113624196,-1.148098026,0.044831746,0.089955153,0.083581477,0.046410074,0.088886555,0.166896154,0.012933317,0.047663718,0.140662371,0.08658602,-1.109863699,-1.186332352,0.61273723,1.337322484,-9.264624138,-10.62744516,-7.433961143,-10.2561225,-9.743552338,-8.262039551,-6.508300501,-3.475806536 -1573,V106T,-0.004166725,0.106082551,-0.014765834,0.115543503,-0.284868942,-0.034643658,-0.021251434,0.012917985,-0.008954843,0.181032778,0.031132324,-0.010257981,-0.019273687,0.145199646,0.085887359,-0.146097329,-0.423640554,1.357433622,2.301876832,-6.204095334,-7.140181694,-5.323703659,-5.814735191,-7.298429619,-5.443426506,-6.224109532,-2.204239832 -1574,V106W,-0.111445906,0.078158987,0.01277218,0.019560071,-0.962883795,0.006305862,-0.146808215,-0.076083596,-0.218214465,0.161174093,-0.00485612,0.169597638,-0.144053279,0.157294513,-0.118174372,-0.487857842,-1.437909748,0.42523862,1.381839624,-10.81550948,-12.79052549,-9.126807678,-11.26203549,-11.06705296,-9.831125771,-8.076518254,-4.633024309 -1575,V106Y,0.028857358,0.095952232,0.051393241,0.121735979,-0.819350791,0.034884699,0.007312598,0.050402117,0.017874724,0.164607268,0.027297196,0.05449699,0.048289492,0.195366255,0.048105702,-0.511698751,-1.127002831,0.419289265,1.376233981,-9.286566808,-11.21969217,-9.678760376,-9.05721402,-8.415551308,-8.061616165,-7.091078836,-2.737339648 -1576,T107A,-0.006745242,0.010280365,0.013892705,-0.046326133,-0.089299781,-0.026221223,-0.010337358,-0.003153125,0.036724017,-0.032239185,0.052799914,0.018056459,0.009728951,-0.050041479,-0.042610786,-0.046455531,-0.13214403,1.412415236,2.500169302,-3.904209328,-4.29679451,-4.384091667,-2.63400798,-4.140134941,-4.06601754,-4.34101915,-1.28344751 -1577,T107C,-0.046131949,0.060852151,0.023562797,-0.006236448,-0.246232592,0.090840326,-0.06875782,-0.023506078,-0.104646638,0.085103453,0.036600848,0.091749735,-0.044624141,0.040800355,-0.05327325,-0.104049641,-0.388415542,1.191664345,2.182603877,-8.184400816,-8.692845314,-8.618500549,-7.138534439,-6.513374069,-9.95874971,-6.542029009,-4.333888698 -1578,T107E,0.070681838,-0.631584843,-1.871881046,-2.066562826,-2.651337332,0.054069537,0.125920969,0.015442707,-0.065728571,-0.71560066,-0.547569026,-1.605759241,-2.13800285,-2.20330164,-1.929824011,-2.676197619,-2.626477045,2.91840322,1.046559996,-11.18889634,-11.18801355,-11.73426835,-10.21353255,-10.90371111,-11.90495614,-7.997672378,-5.417052637 -1579,T107D,-0.029319077,-0.58983647,-1.88319168,-2.301452476,-2.735711985,0.040869295,-0.024600093,-0.03403806,-0.139157489,-0.657174635,-0.522498305,-2.360246573,-1.406136787,-2.258818968,-2.344085983,-2.731714947,-2.739709022,0.832698938,-0.459474108,-10.77704053,-11.25618,-13.08950011,-9.836159431,-10.01746719,-9.685895897,-8.043100848,-4.503289572 -1580,T107G,-0.081765766,0.004073598,-0.018747262,-0.39933271,-1.84055421,0.047757681,-0.072971643,-0.090559888,-0.134083124,0.012279334,-0.004132139,-0.005657985,-0.031836538,-0.17513722,-0.623528199,-1.997982837,-1.683125582,1.130332825,1.313335171,-9.883430327,-10.46779593,-9.145671265,-8.780298225,-9.765120949,-11.25826527,-7.630179922,-3.528947717 -1581,T107F,-0.052304069,0.069895198,-1.102515441,-2.264042075,-3.047786586,0.050149556,-0.015087841,-0.089520296,0.118795855,0.051280162,0.088510234,-1.094313917,-1.110716964,-1.862118031,-2.665966118,-3.033984015,-3.061589157,2.314948436,1.00319852,-10.96099193,-10.00413546,-13.30559003,-9.857818909,-8.631354546,-13.00606072,-6.666560358,-3.292247872 -1582,T107I,-0.038382055,0.011377337,0.01577585,-0.187616436,-1.853374251,0.047886449,-0.011256055,-0.065508054,-0.040904988,0.001219327,0.021535346,0.049542708,-0.017991008,-0.127972152,-0.247260719,-1.683653502,-2.023095,0.964594829,1.330277399,-7.536819572,-6.877027893,-9.259155769,-6.864325478,-6.093530548,-8.590058174,-5.366195426,-2.236196538 -1583,T107H,-0.15235711,-0.589588692,-1.600653468,-2.125854173,-2.992764396,0.020440643,-0.099608265,-0.205105955,-0.043452177,-0.555518187,-0.623659196,-1.552132099,-1.649174836,-1.965614309,-2.286094036,-2.701751724,-3.283777067,3.035158485,1.28948879,-13.29870722,-14.08022835,-14.36021736,-12.05296189,-11.68835439,-14.31177409,-8.190428629,-5.185301383 -1584,T107K,-0.10607589,-0.879879089,-1.856462104,-2.542279501,-2.826024012,0.081818737,-0.086326053,-0.125825726,0.005627337,-0.853552391,-0.906205786,-1.81834459,-1.894579618,-2.620006972,-2.464552029,-2.791872956,-2.860175068,2.02188291,0.165689055,-11.29827376,-11.01718398,-13.43854657,-10.51215192,-10.65620234,-10.86728398,-7.673180941,-3.7253785 -1585,T107M,-0.051601632,0.002363175,-0.034747813,-0.124915125,-1.95630099,0.012062908,-0.048998271,-0.054204992,-0.112471975,-0.083563788,0.088290138,-0.032598527,-0.036897098,-0.080140588,-0.169689661,-1.610892777,-2.301709203,0.912097357,1.330147775,-8.216527464,-7.041995087,-10.02701324,-7.393778656,-6.424787277,-10.19506306,-6.212597858,-2.572752913 -1586,T107L,-0.074287777,0.006246472,-0.043664057,-0.043679744,-0.66359724,0.029544039,-0.052937431,-0.095638123,0.108238994,0.007016871,0.005476073,-0.013739462,-0.073588651,-0.038803311,-0.048556177,-0.455369717,-0.871824763,1.463996882,1.857108215,-7.606464368,-6.389024582,-10.10613092,-6.134499817,-5.83137796,-9.571288559,-5.718375816,-0.767916582 -1587,T107N,-0.209311849,-0.050723141,-0.071298341,-1.337212398,-2.709002539,0.069793536,-0.19302995,-0.225593747,-0.049934304,0.017208892,-0.118655174,-0.011404798,-0.131191883,-1.226366944,-1.448057851,-2.495142941,-2.922862136,0.649874505,0.721952619,-9.746452257,-10.96557829,-11.53718527,-9.931805458,-9.699254951,-6.598437309,-7.882789742,-3.923707596 -1588,T107Q,-0.09114126,-0.645504764,-1.7177096,-2.224016025,-2.808790532,0.045515108,-0.053032123,-0.129250396,-0.274612344,-0.578222977,-0.712786551,-1.546268334,-1.889150866,-1.988908772,-2.459123277,-2.762834748,-2.854746316,3.044082534,1.24977112,-11.11122651,-11.19680244,-11.9483197,-10.33884042,-9.571616608,-12.50055339,-7.323304399,-2.593493499 -1589,T107P,-0.082385536,-0.742991571,-1.623525057,-2.071185571,-2.692235412,0.014034158,-0.080294165,-0.084476906,0.047424915,-0.69042979,-0.795553351,-1.638500477,-1.608549637,-2.051518449,-2.090852692,-2.448026083,-2.93644474,3.675889112,1.831969524,-10.66188441,-9.054914162,-11.11852548,-10.11252228,-11.26722214,-11.75623798,-7.425574601,-5.195922235 -1590,T107S,-0.063023453,-0.002286058,-0.020659847,-0.037549822,-0.120848921,0.006681967,-0.059511982,-0.066534923,0.020251944,-0.004162211,-0.000409905,0.005252621,-0.046572315,-0.056939616,-0.018160028,-0.06069739,-0.181000452,1.494747591,2.571027563,-3.943672563,-4.82815535,-3.773148529,-3.93549456,-4.454940285,-2.726624092,-3.861202154,-1.830842332 -1591,T107R,-0.096467989,-0.91830941,-1.739487519,-2.12219694,-3.115506105,0.070291051,-0.079894087,-0.113041891,0.062058008,-0.871074436,-0.965544383,-1.583048769,-1.895926268,-2.021533248,-2.222860631,-3.369490491,-2.861521718,2.956030648,1.082917297,-10.35652335,-10.3496273,-8.388540932,-10.63298698,-9.757784332,-12.65367719,-7.152128635,-1.416514441 -1592,T107W,-0.092796846,-0.208233491,-2.018788625,-2.315530396,-2.837835535,-0.056818785,-0.074784681,-0.11080901,0.124150972,-0.170884898,-0.245582083,-1.943283327,-2.094293922,-2.620006972,-2.011053819,-2.791872956,-2.883798113,0.704593385,-0.107056604,-14.99517335,-14.28831615,-16.59741884,-13.52005363,-13.13989748,-17.43018063,-10.67972857,-9.388821529 -1593,T107V,-0.066099553,0.055780316,-0.020894247,-0.015299563,-0.579767453,0.040601554,-0.058921176,-0.073277929,-0.14086984,0.043549062,0.06801157,0.049542708,-0.091331202,-0.012202251,-0.018396875,-0.354594783,-0.804940123,1.213534075,1.776024011,-6.503037901,-6.539518715,-8.185112671,-4.971032082,-4.669794441,-8.149731598,-5.938536115,-2.713634532 -1594,T107Y,-0.122312517,-0.17789928,-1.342013136,-1.883432763,-2.788696299,0.033194758,-0.122094413,-0.12253062,0.089173388,-0.03812146,-0.3176771,-1.134937291,-1.54908898,-1.869652883,-1.897212642,-2.585586912,-2.991805685,2.579685884,1.19681407,-13.25593437,-13.33255616,-15.33804868,-11.69383807,-10.44134105,-15.47388791,-8.388545527,-4.420660361 -1595,E108A,0.04423713,0.05940076,0.101527024,0.064489462,0.055104957,0.007468576,-0.017011613,0.105485872,-0.223351347,0.074562435,0.044239084,0.077696866,0.125357182,0.103604613,0.025374311,0.04281331,0.067396603,1.056413169,2.781572971,-4.817972856,-5.24288578,-4.185154137,-5.720643463,-3.876540726,-5.064640175,-4.751247602,-1.431641436 -1596,E108C,0.054647535,0.070085315,0.046737695,0.059532193,-1.109340326,0.028800658,0.014324639,0.094970431,-0.025339585,0.087268521,0.052902109,0.077734074,0.015741316,0.133154422,-0.014090036,-1.073348756,-1.145331895,0.476470085,1.326397574,-9.947922702,-10.626047,-9.115237099,-12.03734997,-9.39135051,-8.569628929,-7.924446742,-5.26608638 -1597,E108D,0.050245731,0.078316246,0.052930784,0.01712767,0.006982199,0.050361434,0.042026169,0.058465293,-0.119420308,0.01310759,0.143524902,-0.002897239,0.108758807,0.046746971,-0.012491632,-0.025313459,0.039277856,1.148165013,2.480467834,-5.394160091,-6.159121452,-6.127450806,-4.525999634,-4.605263603,-5.552964958,-5.135150605,-1.269333176 -1598,E108G,0.029924597,0.050773349,0.016068095,0.046607315,0.010259221,-0.011323512,-0.0219643,0.081813494,-0.142452984,0.05974401,0.041802687,0.042758412,-0.010622223,0.106598376,-0.013383746,-0.02113054,0.041648982,1.193938266,2.61408574,-4.171162999,-3.976314926,-3.64113588,-4.951774498,-3.597467308,-4.689122383,-3.321877758,-1.152292359 -1599,E108F,-0.038087241,0.051248234,0.028130652,0.019042923,-0.262698042,0.016159505,-0.084279746,0.008105264,-0.011020003,0.102229291,0.000267176,0.071279352,-0.015018048,0.072847951,-0.034762106,-0.1685956,-0.356800483,1.321788369,2.165848299,-10.0088961,-10.22869862,-9.456073738,-12.22584662,-9.875491913,-8.258369591,-6.313327503,-3.428324067 -1600,E108I,0.062025548,0.062434923,0.069933971,0.011138465,0.030259801,-0.027639243,0.038953136,0.08509796,-0.184538487,0.034166685,0.09070316,0.10473664,0.035131301,0.115425542,-0.093148612,-0.030945539,0.091465141,1.543610422,3.106887046,-8.746913054,-8.267344162,-8.219911423,-10.51618153,-8.458154129,-8.272974022,-6.81128893,-3.622854257 -1601,E108H,0.090265595,0.068075236,0.048499138,0.032717391,-0.082148876,0.000195969,0.018549665,0.161981525,-0.148419832,0.081476417,0.054674055,0.043498451,0.053499825,0.08656918,-0.021134398,-0.038076016,-0.126221735,1.671448915,3.643209181,-9.058062598,-10.42551437,-8.489283936,-10.21726593,-9.273630562,-6.884618195,-6.096879405,-2.44755244 -1602,E108K,-0.061698443,-0.03527386,0.076369076,-0.149806089,-0.05218598,-0.01648107,-0.164000823,0.040603937,0.069635928,0.076918666,-0.147466386,0.180345326,-0.027607175,-0.016236921,-0.283375257,-0.030691788,-0.073680172,1.29941169,2.618994937,-2.106798457,-2.186979279,-1.405972923,-2.926469078,-2.754272484,-1.260298523,-2.115627396,-0.895699884 -1603,E108M,0.088772149,0.038777772,0.086781236,0.007764833,0.073928831,0.029826925,0.108707003,0.068837295,-0.039508541,-0.000991232,0.078546776,0.084252937,0.089309535,0.072626054,-0.057096389,-0.022489723,0.170347384,1.218791872,2.532598216,-8.469021992,-7.661807037,-7.236786781,-10.54538815,-8.935709282,-7.965418716,-6.805817774,-4.08540542 -1604,E108L,0.008678048,0.025322803,0.015932696,0.010233584,-0.112487897,0.002339014,-0.033913545,0.051269641,-0.195181895,0.04161799,0.009027616,0.048832887,-0.016967495,0.090947196,-0.070480029,-0.076247616,-0.148728178,1.133834381,2.326636976,-8.591837093,-8.73566259,-7.366637756,-10.66653706,-9.313436378,-6.876911682,-6.267414425,-3.562636949 -1605,E108N,0.007584229,0.012707599,0.069950948,0.063434422,-0.012370212,-0.021528806,-0.060105682,0.075274139,-0.258832316,0.108064615,-0.082649417,0.107229619,0.032672276,0.132516613,-0.005647769,-0.004269147,-0.020471276,1.119145782,2.679590251,-7.43491279,-9.214789658,-7.133388252,-8.098134254,-7.579346848,-5.148904938,-6.00527237,-2.414364831 -1606,E108Q,-0.074604371,-0.020977038,-0.013693517,-0.023986554,-0.029396715,-0.001302233,-0.143456413,-0.005752329,-0.1588434,0.047028569,-0.088982645,-0.00892674,-0.018460294,0.039877355,-0.087850463,-0.011764212,-0.047029218,1.671448915,3.643209181,-3.832586317,-3.873794868,-3.199175758,-4.513622826,-3.400896736,-4.175441399,-4.455707267,-0.886107006 -1607,E108P,0.025526204,0.043687102,0.072138572,0.038882905,-1.062669137,-0.017015042,0.004882365,0.046170042,-0.197329827,0.054817354,0.032556849,0.063647016,0.080630128,0.097471184,-0.019705375,-0.981395308,-1.143942966,0.36817852,1.3246697,-8.266399173,-8.056739136,-6.900642075,-9.11571946,-7.30249144,-9.956403755,-5.655171541,-2.840339532 -1608,E108S,0.066924184,0.069532613,0.091963112,0.040856756,0.054907278,-0.004265635,0.025985886,0.107862481,-0.173868352,0.096537918,0.042527308,0.066484328,0.117441896,0.100333164,-0.018619653,0.051277842,0.058536713,1.192749345,2.899060896,-3.753209227,-4.338897964,-2.393295334,-5.184978912,-3.884992271,-2.963881653,-3.199792064,-1.273824206 -1609,E108R,0.052082248,0.044000145,0.043302612,0.031351358,-0.043445211,0.016199359,-0.013462402,0.117626898,-0.127270399,0.060784877,0.027215412,0.060077783,0.026527441,0.078897439,-0.016194723,-0.015352352,-0.07153807,1.114053806,2.46394564,-4.908377353,-6.642658577,-4.083071129,-5.766293365,-4.092625381,-3.957238312,-3.648189251,-1.471602502 -1610,E108T,0.015862006,0.040637482,0.04021724,0.010824258,-0.02672906,0.018528503,-0.023118125,0.054842137,-0.102662342,0.073273288,0.008001675,0.043322022,0.037112458,0.092922385,-0.07127387,-0.008909354,-0.044548766,1.306881923,2.817773842,-5.288671318,-6.871187172,-5.026187279,-6.433666,-4.507327255,-3.604988884,-5.186376055,-2.190113563 -1611,E108W,-0.014283801,0.0358252,0.019013858,0.055401382,-0.423567818,0.0347198,-0.001385831,-0.02718177,-0.43551405,0.079808194,-0.008157794,0.022076646,0.015951069,0.121235302,-0.010432539,-0.389852841,-0.457282795,0.478564286,1.417825828,-10.55188933,-9.672628952,-9.927555717,-11.53928992,-10.20073944,-11.41923262,-6.383179094,-2.628107846 -1612,E108V,0.058347243,0.042376881,0.034249179,0.05983645,0.021242084,-0.016108232,0.024756272,0.091938214,-0.157816699,0.026484735,0.058269026,0.041207893,0.027290465,0.094391461,0.025281438,0.000470871,0.042013296,1.22191688,2.693886263,-8.081966182,-7.517504089,-7.391281372,-9.934244606,-7.481418243,-8.085382599,-6.827085286,-3.355521 -1613,E108Y,0.017741002,-0.014282467,0.058323004,-0.031823613,-0.185633878,0.013022339,0.01348771,0.021994294,-0.285078926,-0.016231198,-0.012333735,0.079489147,0.03715686,0.090449739,-0.154096965,-0.103935605,-0.267332151,1.264393939,2.307717902,-9.676736302,-9.710886009,-9.791089394,-11.91658926,-9.4297323,-7.535384552,-6.779077156,-1.424144819 -1614,K109A,0.02844406,0.046878381,0.03504426,0.029736288,0.017570764,0.043498195,0.048005702,0.008882418,0.036429266,-0.01956826,0.113325022,0.011890379,0.05819814,-0.031857893,0.091330469,-0.009999934,0.045141462,1.132987694,2.327309098,-4.353227469,-3.785223808,-4.974219399,-3.858998016,-6.278419029,-2.869277092,-4.4666974,-0.971510338 -1615,K109C,-0.027875421,0.073119575,0.001624047,0.039279574,-0.977215953,0.059233019,0.049443436,-0.105194277,0.192399601,0.024353376,0.121885773,0.041275955,-0.038027861,0.0040354,0.074523748,-0.623321397,-1.331110509,0.882893779,1.451681311,-9.029963824,-9.753609062,-9.405678879,-9.001555229,-9.783966545,-7.205009407,-7.470204853,-2.454464573 -1616,K109E,-0.000292405,-0.001584097,0.013331059,-0.013742216,-0.046458354,0.026554889,0.042322642,-0.042907451,0.098374751,-0.040287743,0.037119549,-0.015904589,0.042566707,-0.069310542,0.04182611,-0.067520377,-0.02539633,1.340688798,2.403209717,-3.799258302,-2.601505898,-4.471028015,-4.480221123,-4.301773735,-3.141762741,-4.332568487,-0.688184265 -1617,K109D,-0.014672826,0.011774978,0.002799436,-0.016769497,-0.042958069,0.057486722,0.043002433,-0.072348085,0.158046756,-0.036312283,0.059862238,-0.01140437,0.017003242,-0.081347592,0.047808598,-0.091081368,0.005165231,1.362664798,2.259569601,-5.181684586,-3.136458916,-6.395323715,-5.259214447,-5.50312394,-5.61430191,-4.741204381,-1.555315251 -1618,K109G,0.002672515,0.047687515,0.019483749,0.007406547,-0.006431754,0.0232358,0.029711275,-0.024366246,0.200450605,-0.021930058,0.117305087,0.033183047,0.00578445,-0.034426678,0.049239772,-0.028513605,0.015650098,1.481553083,2.665887239,-6.023096526,-5.08488327,-7.091028641,-5.441892776,-6.82598082,-5.671697121,-5.566770764,-2.337747721 -1619,K109F,0.024535318,0.095536672,0.079844958,0.073698489,-0.125324548,0.018485132,0.04040084,0.008669795,-0.061269657,0.014932932,0.176140412,0.045900542,0.113789374,-0.038426149,0.185823127,-0.160404393,-0.090244703,1.324858101,2.14707842,-9.482551186,-11.86960992,-9.504344254,-9.07549144,-9.866027016,-7.097283295,-6.876971451,-1.540484464 -1620,K109I,-0.039742176,-0.053011092,0.043483998,-0.021389766,-0.063511355,0.020715605,-0.006954792,-0.07252956,-0.368489227,-0.0540708,-0.051951384,0.091192051,-0.004224056,-0.074264574,0.031485043,-0.082467058,-0.044555651,1.417804283,2.340412478,-8.714991187,-9.287385994,-7.74149324,-8.217804825,-8.864197014,-9.46407486,-7.24171599,-3.532216432 -1621,K109H,-0.078775275,0.009830945,0.01970605,-0.017491392,-0.05099694,0.018876802,-0.074524471,-0.083026079,0.018443487,-0.010319856,0.029981745,0.032826065,0.006586034,-0.012552737,-0.022430047,-0.034888048,-0.067105831,1.171423235,2.36905779,-4.774241693,-5.712094467,-4.953259239,-4.669883698,-5.596277359,-2.939693703,-6.139817371,-1.94328294 -1622,K109M,-0.006816332,0.046203492,0.002561437,0.055370333,0.041160179,0.015175306,0.038773977,-0.05240664,0.080310751,-0.020278637,0.112685621,-0.000982326,0.006105199,-0.032131464,0.14287213,0.010067186,0.072253171,1.201458267,2.637069567,-6.439143172,-7.202456757,-6.757499825,-6.974284988,-6.128202278,-5.133272011,-7.01634083,-2.212230898 -1623,K109L,0.024717412,0.026432294,0.037757098,0.046900884,0.011094306,0.015152957,0.061901703,-0.01246688,0.059906795,0.005091436,0.047773152,0.038330667,0.037183528,0.002928705,0.090873063,-0.002426671,0.024615283,1.158967774,2.513753771,-5.065708559,-6.16477417,-6.216175911,-4.464871567,-4.271160713,-4.211560432,-5.100827861,-1.322448304 -1624,K109N,-0.019115399,0.043923962,0.033537661,0.050502123,0.031006255,0.003545671,-0.007555361,-0.030675437,-0.020059794,0.026066452,0.061781471,0.085029987,-0.017954666,0.018136731,0.082867514,0.060654988,0.001357522,1.247259612,2.952494681,-3.295075883,-2.149512573,-3.837780579,-3.887907753,-3.323223114,-3.276955399,-4.851799407,-1.91274472 -1625,K109Q,-0.011806025,0.023379151,0.060186079,0.061298219,0.015313737,0.045651698,0.035043181,-0.05865523,-0.073786214,0.046121526,0.000636775,0.125620494,-0.005248336,0.005176029,0.117420409,0.031025984,-0.000398511,1.349514821,2.839101128,-1.770776248,-1.491281937,-1.660228012,-2.173121521,-2.147014755,-1.382235016,-2.535952549,-0.890693142 -1626,K109P,-0.006093254,0.02762997,0.021596887,0.004347282,-0.973440827,0.067834302,0.024208274,-0.036394782,0.15166666,-0.024876491,0.08013643,0.004595882,0.038597891,-0.046332934,0.055027498,-0.714737675,-1.232143978,0.780478639,1.406942838,-5.760922615,-6.833852463,-6.02622628,-3.940642632,-6.910540939,-5.093350761,-5.372931787,-1.836542503 -1627,K109S,-0.00356124,0.015488962,0.026857679,0.021227856,-0.01347513,0.007251985,0.032232027,-0.039354507,0.12458144,-0.055158248,0.086136172,0.044291241,0.009424116,-0.039920473,0.082376184,-0.028478978,0.001528718,1.25549214,2.396280602,-5.521957959,-5.40689595,-5.322072952,-5.509878998,-6.807999535,-4.56294236,-5.937251974,-1.636311692 -1628,K109R,0.03040023,0.046499582,0.034492993,0.030856778,0.007215051,0.009392594,0.062332983,-0.001532523,0.121597005,-0.038441381,0.131440544,0.023714845,0.04527114,-0.022369304,0.084082859,-0.033042678,0.04747278,1.411803633,2.550622049,-3.105393628,-3.752966309,-2.538917099,-2.988654083,-3.985463951,-2.260966698,-3.743749663,-0.975005814 -1629,K109T,0.038970563,0.066313822,0.055206076,0.052106105,0.002104742,0.013535529,0.08414337,-0.006202245,0.229572444,-0.021937414,0.154565058,0.03030905,0.080103101,-0.002941022,0.107153232,-0.019370109,0.023579592,1.181000236,2.530186669,-3.641806458,-2.583330475,-4.192586929,-4.033372467,-4.976899162,-2.422843254,-4.421138463,-1.577395446 -1630,K109W,-0.010106988,0.052725192,0.04005632,0.021347414,-0.11899215,0.028891633,0.014321028,-0.034535003,0.142850326,0.006723125,0.098727258,0.055397751,0.024714888,-0.028193256,0.070888084,-0.122814947,-0.115169353,1.247671284,2.168986241,-9.504720107,-11.28918531,-10.07206214,-8.715817863,-9.138697769,-8.307837448,-7.087690927,-3.364136604 -1631,K109V,-0.001895956,0.009295376,-0.004236476,0.001333875,-0.035012295,0.020518336,0.03358644,-0.037378352,0.020425816,-0.055035553,0.073626305,0.007891389,-0.01636434,-0.035711048,0.038378797,-0.062937337,-0.007087253,1.327578822,2.422303233,-7.798070059,-9.234369728,-7.187826645,-7.569894791,-8.599716835,-6.398542297,-7.000823671,-2.702764064 -1632,K109Y,0.004076891,0.053019665,0.02609488,0.033641295,-0.101598564,0.011192236,0.038526223,-0.030372442,0.19266036,0.001490611,0.104548718,0.018088259,0.034101501,-0.008622444,0.075905033,-0.067302713,-0.135894415,1.219987286,2.328097342,-9.082824135,-11.67648757,-9.34545668,-8.764673683,-9.667875549,-5.95962719,-6.58106454,-1.890227971 -1633,H110A,0.038637755,0.077784625,0.034206373,0.030551256,-0.180897312,0.047387519,0.011621886,0.065653623,0.010695158,0.092088383,0.063480866,0.052462227,0.015950518,0.067023073,-0.005920562,-0.143030748,-0.218763876,1.319181323,2.225443106,-5.844996631,-7.387093056,-6.263704712,-5.084287239,-4.557429405,-5.932468742,-5.835245925,-1.69919104 -1634,H110C,0.031304961,0.000502866,0.001443156,0.002518984,-0.942352686,0.095586062,0.035427066,0.027182856,-0.181501802,-0.062912505,0.063918237,-0.036075143,0.038961454,-0.092512871,0.097550838,-0.642132943,-1.242572428,1.428927681,1.707311847,-9.454433798,-11.0984863,-10.53846781,-8.20671666,-8.391663086,-9.036835136,-8.398658036,-5.707223483 -1635,H110E,0.067938409,0.069692113,0.082693061,0.057591152,-1.050391483,0.099180611,0.099041001,0.036835816,0.018173969,0.00603821,0.133346015,-0.013630645,0.179016766,-0.017055446,0.132237749,-0.953263266,-1.1475197,0.868901074,1.388280504,-8.832541965,-10.15199719,-11.00059943,-7.37324115,-7.174894814,-8.461977234,-6.625025449,-2.722010828 -1636,H110D,0.073783953,0.132924741,0.127604283,-0.469381462,-1.824052084,0.060888529,0.056869778,0.090698128,-0.345003933,0.044416445,0.221433037,0.067032475,0.188176091,-0.27143342,-0.667329504,-1.856353253,-1.791750915,1.32213546,1.350662228,-7.923399594,-8.729996796,-7.145591476,-7.283502876,-6.985531204,-9.472375618,-6.902109617,-2.851297565 -1637,H110G,0.046511183,0.071084305,0.042653119,0.052788706,-0.224713885,0.111818441,0.02718088,0.065841486,-0.137006296,0.035292979,0.106875631,0.030255646,0.055050592,0.023714393,0.081863019,-0.203686384,-0.245741386,1.508372056,2.252694637,-8.531174968,-10.52473109,-8.708365738,-7.808646507,-6.832405388,-8.781726112,-6.802260489,-4.125594996 -1638,H110F,0.005827308,-0.014051914,0.061629028,0.003411133,-0.053775393,-0.027656737,0.025612084,-0.013957469,-0.168912674,0.112190972,-0.140294799,0.052958847,0.070299209,0.020939256,-0.01411699,0.021442298,-0.128993083,1.139725805,2.466694997,-4.711570827,-6.490245811,-4.993813049,-4.356510452,-3.585692047,-4.131592773,-5.222799118,-1.063678543 -1639,H110I,-0.18625944,-0.054139144,-0.169448335,-0.391798994,-1.990195929,0.023401997,-0.198251957,-0.174266922,0.065170532,-0.043935765,-0.064342523,-0.099651316,-0.239245353,-0.231138825,-0.552459162,-1.555323257,-2.4250686,1.444762461,1.426472939,-9.154582874,-9.748728722,-9.221094566,-9.275327873,-8.635115891,-8.892647316,-7.132626362,-3.517522407 -1640,H110K,0.157759792,0.117709009,0.064340507,0.106977237,0.012441677,-0.002515573,0.117059201,0.198460382,0.257056058,0.041950766,0.193467251,-0.01833594,0.147016954,-0.013672115,0.227626588,-0.081207512,0.106090865,1.316692716,2.348542741,-6.15234933,-8.230588623,-5.487371819,-5.883220177,-5.427245926,-5.733320107,-6.072108159,-1.827919626 -1641,H110M,-0.055114977,-0.012243677,0.005485667,-0.00033342,-0.156592771,0.085418282,-0.066797428,-0.043432525,-0.110920727,-0.000301968,-0.024185385,-0.010924752,0.021896086,-0.019750146,0.019083306,-0.1165173,-0.196668241,1.23962028,2.164649125,-8.188103514,-8.968504379,-7.134278877,-9.57928717,-7.845468613,-7.412978531,-6.188690228,-2.203635534 -1642,H110L,0.048633537,0.037931989,-0.002580328,0.030381736,-0.418581883,0.105899845,0.063006011,0.034261063,-0.079971591,0.025331112,0.050532866,-0.013807924,0.008647268,-0.018326977,0.079090449,-0.333150528,-0.504013238,0.997792134,1.620671574,-7.004101031,-7.95456192,-6.263857124,-7.620977005,-6.166353874,-7.014755234,-4.835962873,-0.792689715 -1643,H110N,0.001891826,-0.015215195,-0.021520455,-0.005085763,-0.016681125,0.056325555,-0.043714408,0.04749806,-0.19239377,-0.064419467,0.033989077,-0.036860486,-0.006180423,-0.069328729,0.059157203,-0.028601173,-0.004761076,1.31205633,2.46737095,-4.140912529,-4.916292992,-3.940857819,-3.973261368,-4.265060349,-3.609090118,-4.344040311,-1.43195963 -1644,H110Q,0.021155674,0.059326207,-0.023658293,-0.012208962,-0.231536315,0.063621163,0.04409549,-0.001784143,-0.117760152,0.056877652,0.061774761,-0.031228214,-0.016088371,0.040261915,-0.064679839,-0.183592233,-0.279480396,1.228587236,2.001724344,-5.553862802,-6.647646324,-6.199977646,-4.978148323,-4.475428024,-5.468113693,-6.221746768,-2.213554205 -1645,H110P,0.033783594,0.058611995,0.0068167,-1.489324481,-2.301066404,0.074725595,0.059368099,0.008199088,-0.115721575,0.032301478,0.084922511,0.007755535,0.005877864,-1.318417957,-1.660231005,-2.184386165,-2.417746642,0.510283558,0.70543257,-9.39150408,-10.94757689,-9.635793678,-8.409570442,-7.976939728,-9.987639664,-6.995360406,-2.547429062 -1646,H110S,0.149701731,0.131534928,0.103573376,0.064524863,-0.160450531,0.07679719,0.173644923,0.125758539,-0.130378543,0.063867348,0.199202508,0.040630655,0.166516097,0.010896077,0.118153649,-0.191646452,-0.12925461,1.275083748,2.043950382,-7.442917828,-7.801526009,-8.396411842,-6.106453781,-6.56011412,-8.350083389,-6.678400827,-2.84462119 -1647,H110R,0.057305195,0.066930269,0.036511361,0.055122012,-0.059301023,0.027311384,0.054205927,0.060404463,-0.061007277,0.038711062,0.095149475,0.034448441,0.038574281,0.019603164,0.09064086,-0.030992706,-0.087609339,1.236077704,2.567918366,-3.375171178,-4.200438255,-3.469648842,-3.336930481,-2.489448105,-3.379390205,-3.406585411,-0.685438714 -1648,H110T,0.100636716,0.110553117,0.043779389,0.104210381,-1.55125933,0.056698258,0.111180129,0.090093302,-0.275923014,0.060139475,0.160966759,0.020488538,0.067070239,0.077575526,0.130845236,-1.544327873,-1.558190786,0.60515725,1.313752295,-7.573074098,-8.246716034,-7.85227388,-7.697088394,-6.809079788,-7.260212395,-6.061448112,-3.30187053 -1649,H110W,0.087682249,0.054165231,0.010769338,0.048566727,-0.560469723,0.112863156,0.0827058,0.092658698,-0.130283272,0.04293783,0.065392632,0.077789256,-0.056250581,0.042308541,0.054824913,-0.404916423,-0.716023023,0.609118759,1.449400134,-8.208751024,-11.12367922,-10.12506767,-7.212851906,-5.4263741,-7.155782219,-5.23797326,-3.308831413 -1650,H110V,0.058491357,0.081290441,-0.00890535,0.018520619,-1.741210232,0.100334431,0.095954469,0.021028244,-0.047490512,0.016437307,0.146143575,0.009018255,-0.026828955,0.010183534,0.026857703,-1.592465065,-1.889955398,0.460026354,1.305268325,-7.610896207,-7.759206841,-7.096888725,-8.411404305,-7.633542915,-7.153438248,-5.849242852,-2.359017037 -1651,H110Y,0.114829691,0.177005297,0.175593952,0.045922594,0.104755124,0.02413368,0.065483596,0.164175785,0.052936075,0.066170598,0.287839995,0.12646296,0.224724944,0.075071965,0.016773223,0.052340612,0.157169635,1.283942732,2.878264802,-3.300712282,-2.744105621,-3.642023445,-3.458591728,-3.026820534,-3.632020081,-4.218799341,-1.042674641 -1652,L111A,-0.02653579,-0.035827894,-0.003869327,-0.057030278,-0.178922149,-0.004677636,-0.018803564,-0.034268016,-0.046270399,-0.03257593,-0.039079857,0.012577041,-0.020315694,-0.068047673,-0.046012883,-0.097705441,-0.260138856,1.49477802,2.415633588,-3.908242934,-4.663923927,-2.702965294,-3.877145226,-3.005191589,-5.291988632,-4.194999462,-0.51667604 -1653,L111C,-0.04349062,-0.014662399,-0.026231848,-0.070146843,-0.230763117,0.077583182,-0.029097033,-0.057884207,-0.070120467,-0.039203341,0.009878544,-0.006724233,-0.045739462,-0.04734986,-0.092943826,-0.149381126,-0.312145108,1.487458285,2.284829967,-9.048746159,-9.831974197,-8.909032219,-9.233837776,-8.664613762,-8.604272842,-8.943109678,-5.340484949 -1654,L111E,-0.095685793,-0.082071992,-0.05410163,-0.083557101,-1.001409632,0.005979232,-0.121621496,-0.06975009,-0.112727408,0.0016258,-0.165769783,0.012544762,-0.120748021,-0.035115404,-0.131998797,-0.786243686,-1.216575578,0.866332785,1.414914118,-6.939059985,-7.99704995,-7.194197472,-7.394805855,-6.224513908,-5.884732742,-6.668784054,-1.897208284 -1655,L111D,-0.059369451,-0.017220879,-0.010196289,-0.007861108,-1.705468068,0.001457449,-0.078360172,-0.040378729,0.025089991,-0.001962786,-0.032478972,0.031571559,-0.051964136,0.043677494,-0.05939971,-1.221196037,-2.189740098,0.622015482,1.33147378,-8.097880161,-9.436693169,-9.480560822,-8.544797562,-6.805825386,-6.221523865,-6.328573276,-0.534537639 -1656,L111G,-0.049181958,-0.039091834,-0.010697775,-0.035929492,-1.338578008,0.042470538,-0.04655093,-0.051812985,-0.038032887,-0.005902086,-0.072281581,0.019700956,-0.041096505,0.006800787,-0.07865977,-1.264576194,-1.412579822,0.70107297,1.33468519,-6.916784602,-8.239035568,-3.908784462,-8.019172096,-6.301642998,-8.115287888,-6.61099249,-1.778660712 -1657,L111F,-0.020655987,-0.017356114,-0.032008436,-0.074823386,-0.056213048,0.056454534,0.013239182,-0.054551155,0.090121778,-0.063274707,0.028562479,0.010269241,-0.074286112,-0.108692015,-0.040954756,-0.099169662,-0.013256433,1.515377702,2.418097152,-5.009586122,-6.010768898,-5.300861305,-4.618344093,-5.083234543,-4.034721771,-6.234747921,-2.135161391 -1658,L111I,-0.02350057,0.033284014,-0.017627259,-0.000264236,0.051210423,0.008236486,-0.030142025,-0.016859115,-0.121272989,-0.046381926,0.112949953,0.027495439,-0.062749957,0.06545429,-0.065982762,0.018934282,0.083486563,1.142877423,2.785811829,-2.310262315,-1.844933029,-2.386923943,-2.913589623,-2.0323097,-2.373555283,-3.610687787,-0.765635732 -1659,L111H,-0.064360297,-0.010672719,-0.022777068,-0.028970195,-0.119595027,0.03374217,-0.078189968,-0.050530626,-0.059712108,0.012010477,-0.033355914,0.053295178,-0.098849313,0.020466022,-0.078406412,-0.071874645,-0.167315409,1.229099534,2.361328104,-7.615979767,-9.163797417,-7.909092682,-5.97138414,-7.402978325,-7.632646271,-7.546785667,-1.78749682 -1660,L111K,-0.027043373,-0.054481634,-0.052749002,-0.078842333,-0.445290177,0.029784212,-0.003139714,-0.050947031,0.007045488,-0.112802616,0.003839348,-0.035494525,-0.070003478,-0.043189477,-0.114495188,-0.277948911,-0.612631443,1.440624859,2.005843982,-6.370346674,-7.557965462,-4.472382095,-6.801442451,-5.609434555,-7.410508804,-6.078971082,-1.179979916 -1661,L111M,-0.043207511,-0.064593793,-0.058739247,-0.119021952,-0.008178508,0.007336613,-0.008060951,-0.07835407,-0.169045771,-0.028430092,-0.100757493,0.013794641,-0.131273135,-0.002540273,-0.235503631,-0.035353794,0.018996779,1.267886367,2.607370612,-5.240131137,-5.354148499,-5.195412964,-5.347448067,-5.066250999,-5.237395157,-6.87807075,-3.448098676 -1662,L111N,-0.13494976,0.001111975,-0.025067205,-0.029740506,-1.793923508,-0.019385915,-0.156808964,-0.113090555,-0.010683279,0.025540748,-0.023316799,0.044884775,-0.095019185,0.076203476,-0.135684487,-1.56045107,-2.027395945,0.59848298,1.312623274,-8.124309364,-9.73889315,-7.028220009,-8.740358978,-7.504422256,-7.609652428,-7.664919737,-2.371944116 -1663,L111Q,-0.094078926,-0.029606528,-0.000612256,-0.065447366,-0.08332181,0.059973926,-0.087131956,-0.101025895,-0.128129025,-0.007006692,-0.052206364,0.051911042,-0.053135553,-0.014538768,-0.116355963,-0.109814901,-0.056828718,1.3093394,2.222427284,-5.303983983,-6.573063683,-4.757867134,-4.516465759,-4.780857788,-5.89166555,-5.67076556,-2.105276155 -1664,L111P,-0.057375521,-0.006528281,-0.021040383,-0.033667303,-1.124830808,0.063305069,-0.05090578,-0.063845261,-0.040539914,-0.008809485,-0.004247076,0.020385643,-0.062466409,-0.025640925,-0.04169368,-0.873703836,-1.375957779,0.708401941,1.37035961,-6.565856819,-7.48830378,-6.641046417,-6.400317337,-5.336764175,-6.962852386,-5.629951077,0.211347068 -1665,L111S,-0.053143753,-0.018670079,-0.050277294,-0.042522476,-0.255496117,0.023508764,-0.063845992,-0.042441514,0.014224073,-0.02266183,-0.014678328,-0.017428465,-0.083126123,-0.014656799,-0.070388153,-0.229880109,-0.281112125,1.45657963,2.113026454,-6.028996951,-7.864766106,-5.408120255,-6.184628876,-5.436980957,-5.250488564,-6.322337131,-0.936089205 -1666,L111R,-0.063575711,-0.036546873,-0.007371007,-0.053460171,-0.788257468,0.054496551,-0.074563499,-0.052587922,0.017769353,-0.005450357,-0.067643389,0.005813658,-0.020555672,0.002620139,-0.10954048,-0.576171564,-1.000343372,0.632759499,1.406330142,-5.66368194,-6.512621895,-4.499097954,-4.408205269,-5.616918724,-7.281565857,-6.012748567,-1.388951762 -1667,L111T,-0.01541583,-0.044761405,-0.04337692,-0.03898053,-0.055475814,0.008589567,-0.01452311,-0.016308549,0.011815091,-0.073700385,-0.015822424,-0.046904819,-0.03984902,-0.048655585,-0.029305475,-0.086277376,-0.024674251,1.352615206,2.29140379,-4.091896292,-4.984808578,-3.410825287,-5.029428543,-3.253249275,-3.781169777,-5.008665479,-1.050372661 -1668,L111W,-0.002338791,-0.011565061,-0.027921996,-0.04624976,-0.08093974,0.022875655,0.012230033,-0.016907615,-0.059375203,-0.03076246,0.007632338,0.005132883,-0.060976875,-0.043837929,-0.048661591,-0.111478493,-0.050400987,1.534599217,2.41063141,-8.943880603,-9.99213443,-9.816200333,-8.691106972,-8.473055977,-7.746905304,-8.227982867,-3.719176569 -1669,L111V,-0.000183236,-0.010792247,0.007017452,-0.010388135,0.03501739,-0.056564712,-0.03321218,0.032845709,-0.094185899,-0.030473835,0.008889341,-0.008275879,0.022310783,-0.010045942,-0.010730328,0.001836443,0.068198336,1.1861854,2.528187983,-1.552259564,-1.181892738,-1.418170746,-2.101700302,-0.95222596,-2.107308075,-2.460434255,0.702979705 -1670,L111Y,-0.059021773,-0.016906024,-0.004627352,-0.034095154,-0.079256332,0.011085748,-0.063045356,-0.05499819,-0.17529472,-0.010781251,-0.023030797,0.03847238,-0.047727083,0.032985232,-0.10117554,-0.022514778,-0.135997885,1.140691649,2.405539867,-8.267697539,-9.277981911,-9.192569191,-8.001496536,-7.56608017,-7.300359886,-7.74286341,-3.109384185 -1671,T112A,0.011455862,0.042646225,0.004205864,0.036363413,0.040527258,0.045147429,0.016444668,0.006467055,0.058735864,0.06313674,0.02215571,0.021308083,-0.012896355,0.032891312,0.039835514,0.037868889,0.043185627,1.085105223,2.64713552,1.405103749,1.576309456,1.367824799,1.676786751,0.867921646,1.536676094,-0.960019016,1.894238911 -1672,T112C,-0.079643134,0.031055803,-0.044951537,-0.020494342,-0.224731163,0.080471446,-0.104899887,-0.054386381,0.089680668,0.049570069,0.012541536,0.010023436,-0.09992651,-0.007395281,-0.033593403,-0.228364114,-0.221098212,1.493993453,2.143045545,-4.592858835,-4.582690987,-5.312061211,-3.985145416,-5.907271515,-3.177125046,-6.69245672,-2.146334133 -1673,T112E,0.02122863,0.074811056,0.072928275,0.082174505,0.028461722,0.092016477,0.010184095,0.032273164,0.070287533,0.105308731,0.04431338,0.079731738,0.066124812,0.076083414,0.088265595,0.017743635,0.039179808,1.144345991,2.808653556,-0.953388741,-0.660788353,-1.725560165,0.362041061,-2.475657509,-0.266978737,-3.981641353,1.271451842 -1674,T112D,-0.038839234,0.018815949,-0.034780396,-0.000195934,0.001599065,0.03837516,-0.032881226,-0.044797241,-0.120618955,0.037716698,-0.0000848,-0.021246805,-0.048313986,0.006373179,-0.006765047,-0.004947444,0.008145574,1.543610422,3.106887046,-0.498414029,-0.802948822,-1.167328384,0.809302933,-0.186737663,-1.144358208,-2.772053685,2.145123734 -1675,T112G,0.026610681,0.056156316,0.05185028,0.042714632,0.068757914,0.029777355,0.012004666,0.041216696,0.00193298,0.051880354,0.060432278,0.088674232,0.015026327,0.036638906,0.048790357,0.027814554,0.109701273,1.203076918,2.833734906,-0.499880321,-1.388808327,-0.622971489,1.310886536,-1.536838333,-0.261669991,-3.49745091,2.762128844 -1676,T112F,0.041803513,0.04781826,0.027126255,0.027919667,0.049081384,-0.084056654,-0.001915726,0.085522751,0.067282023,0.039853959,0.05578256,0.01785667,0.036395839,0.027365321,0.028474012,-0.022342141,0.120504908,1.301408296,2.615940903,-6.73074155,-5.78285994,-7.770326294,-6.019188065,-9.100101624,-4.981231827,-6.360780883,-2.217604457 -1677,T112I,0.019470795,0.082002683,0.042175594,0.029017988,0.084895434,0.037864818,0.054533882,-0.015592293,-0.12886903,0.107009108,0.056996257,0.072620428,0.01173076,0.050497642,0.007538334,0.061297064,0.108493804,1.16819842,2.937904517,-4.418763606,-4.290004082,-4.642508095,-3.401336723,-5.748713158,-4.011255974,-6.574473338,-2.185047293 -1678,T112H,-0.054934325,-0.011697365,0.005451869,0.039837585,0.012700159,0.076252052,-0.050813362,-0.059055287,-0.120820577,0.029746814,-0.053141544,0.042293217,-0.031389479,0.053359641,0.026315528,0.023295828,0.002104489,1.142036181,2.733825621,-4.191354694,-4.578929237,-5.161709877,-2.610330185,-5.435196312,-3.170607857,-5.05105806,-0.17606046 -1679,T112K,0.041602994,0.028859506,0.057573624,0.071608766,0.061175424,0.057879866,0.039882918,0.04332307,-0.00885153,0.050966434,0.006752578,0.053555052,0.061592196,0.046076873,0.097140658,0.052379238,0.06997161,1.130137451,2.846691389,-1.203565997,-1.117653549,-2.125583542,0.057271721,-2.341949005,-0.489915611,-3.032705327,0.323976954 -1680,T112M,0.035176819,0.040108987,0.068080856,0.066504614,0.008222842,0.020392238,0.026224226,0.044129411,0.223313488,0.048346213,0.03187176,0.012953793,0.123207918,0.035132327,0.0978769,0.006412079,0.010033605,1.189559922,2.647125377,-5.120463095,-5.235074265,-5.831234932,-4.251454605,-6.573985168,-3.710566505,-6.914458118,-2.699482966 -1681,T112L,-0.020201141,0.014839311,0.025108456,0.051326414,0.012445887,0.026128879,0.003072629,-0.043474911,0.114865561,0.037082585,-0.007403964,0.05513705,-0.004920139,0.037678939,0.064973888,0.011421126,0.013470647,1.085105223,2.64713552,-5.219605275,-4.919007835,-5.966357063,-3.793808258,-6.94035154,-4.478501678,-6.231496266,-1.995860259 -1682,T112N,-0.009063641,0.04443331,0.041230198,0.064226368,0.049527478,0.044450194,0.00014086,-0.018268141,-0.163631136,0.057433773,0.031432847,0.037887996,0.044572399,0.048151461,0.080301275,-0.023630287,0.122685243,1.111723942,2.514871858,-1.343508752,-1.731564529,-1.848088219,-0.824544594,-1.373445076,-0.939901344,-3.486347711,0.987854975 -1683,T112Q,-0.029575915,-0.048014411,-0.076122429,0.005136482,-0.051817832,0.038793821,-0.021353836,-0.037797994,-0.04262593,-0.045223096,-0.050805725,-0.024569542,-0.127675315,-0.014183298,0.024456262,-0.045104423,-0.05853124,1.183851575,2.389461889,-2.875077266,-2.742340439,-3.555123779,-1.441348289,-5.001589821,-1.634984001,-4.287732562,0.064901418 -1684,T112P,0.010092697,0.02156935,0.02324934,0.038241333,-0.018968098,0.025197176,0.018488552,0.001696841,0.037723779,0.067618586,-0.024479886,0.049680034,-0.003181354,0.030507378,0.045975287,0.004426022,-0.042362217,1.671448915,3.643209181,-2.300674808,-2.103926163,-1.792808975,-1.673031273,-5.184353722,-0.749253906,-3.729280301,1.476461483 -1685,T112S,0.01785622,0.012895164,0.004823326,0.022131401,0.018286818,0.021466087,0.025060455,0.010651984,0.020512163,0.005982124,0.019808203,-0.003847701,0.013494353,0.005371847,0.038890955,-0.010130763,0.046704398,1.237023233,2.517427644,-0.600694351,-0.411613327,-0.199223183,-0.368380127,-2.090945038,0.066689919,-3.474092637,0.567603443 -1686,T112R,0.008951165,0.019459039,0.029985338,0.007776676,0.019411118,0.041464363,0.019223758,-0.001321428,0.050982378,0.008553233,0.030364845,0.016862861,0.043107814,0.001666813,0.013886539,-0.027450181,0.066272416,1.184291133,2.48731783,-2.920324733,-3.239659004,-3.224276955,-1.605931664,-4.358470886,-2.173285156,-4.192094414,0.000245234 -1687,T112W,-0.010893508,0.092261628,0.063152755,0.072421922,0.006492854,0.020733544,-0.04275198,0.020964964,0.101579891,0.147517274,0.037005981,0.085212865,0.041092644,0.108257062,0.036586782,0.02663463,-0.013648923,1.110270999,2.803064708,-6.791883339,-6.659152573,-7.382258705,-5.698428352,-8.972465775,-5.24711129,-7.24112777,-3.239852511 -1688,T112V,0.034623584,0.036818457,0.043372126,0.050460389,0.000436853,0.031395998,0.027551501,0.041695666,0.05420835,0.071188232,0.002448681,0.078886421,0.007857831,0.035200922,0.065719856,-0.012663352,0.013537057,1.09141726,2.505512625,-1.938401717,-1.936430649,-1.718351135,-1.661318657,-2.904645248,-1.471262894,-4.61998564,-0.499386432 -1689,T112Y,-0.042348475,0.01752965,0.027047939,0.008257396,0.054425557,0.035622799,-0.081096972,-0.003599977,-0.0248642,0.059336236,-0.024276936,0.101613613,-0.047517736,0.064787049,-0.048272257,0.07249087,0.036360243,1.087675146,2.722527363,-6.289523726,-5.672615829,-8.590038094,-5.148101097,-8.00239341,-4.0344702,-5.997148011,-1.39790749 -1690,D113A,-0.015131512,-0.095492424,-0.061248224,-0.062972207,-0.06605382,-0.001297056,-0.026328939,-0.003934084,-0.421350768,-0.052407105,-0.138577742,-0.113280618,-0.009215829,-0.032594212,-0.093350202,-0.085461554,-0.046646085,1.369038687,2.358196104,-4.294848683,-4.809648605,-3.426271416,-4.006963928,-4.047490753,-5.183868713,-4.894475094,-0.065341751 -1691,D113C,0.079122188,-0.053242532,-0.005413694,-0.044918278,-0.304002288,0.049325737,0.049676465,0.10856791,-0.393912519,-0.070931171,-0.035553892,-0.022601589,0.011774202,0.000105953,-0.089942509,-0.252564429,-0.355440147,1.45712359,2.077991044,-9.300791753,-10.08878091,-8.12403804,-9.510665367,-9.865063843,-8.915410599,-8.93442439,-4.811168197 -1692,D113E,0.07024436,-0.033817562,-0.004989163,0.072579605,-0.005727654,0.025004009,0.139482681,0.001006038,-0.333214679,-0.012064511,-0.055570612,-0.075085944,0.065107619,0.053311881,0.091847328,-0.016031727,0.004576419,0.92629403,2.330417922,-1.364215793,-1.309781219,-1.366298882,-1.738144547,-1.390731384,-1.016122932,-4.054731454,-0.247443031 -1693,D113G,-0.00845206,-0.131759496,-0.024608395,-0.016542548,-0.060906319,0.007929273,-0.031408464,0.014504345,-0.172363387,-0.093598984,-0.169920008,-0.10820284,0.058986051,-0.006475514,-0.026609581,-0.078211174,-0.043601463,1.541373258,2.49883553,-3.552532123,-3.214412148,-3.081349655,-3.437611534,-5.496100082,-2.533187195,-5.7621087,1.177608532 -1694,D113F,0.013360006,-0.054449081,-0.011758665,-0.002033386,-0.231182605,0.057668167,0.001401403,0.025318609,-0.283996656,-0.049593115,-0.059305047,-0.068288553,0.044771223,0.00157129,-0.005638062,-0.267187637,-0.195177572,1.587489219,2.15923086,-9.803046329,-10.62046109,-7.563960442,-10.21429469,-11.85833366,-8.758181763,-8.790789574,-4.549415499 -1695,D113I,0.018361401,-0.055953496,0.003130716,0.021720153,-0.101362692,0.035900992,0.018729767,0.017993034,-0.247784484,-0.021077093,-0.090829898,-0.066688149,0.07294958,0.026251834,0.017188472,-0.128638001,-0.074087382,1.386680422,2.2677355,-7.996512762,-9.105486588,-7.262091255,-7.759926865,-9.577324562,-6.277734543,-7.19297863,-2.139269399 -1696,D113H,0.053154368,-0.097064427,-0.042392569,-0.047713511,-0.034760101,-0.027257313,0.013883598,0.092425137,-0.252181428,-0.118028075,-0.076100778,-0.113215844,0.028430706,-0.04515751,-0.050269511,-0.085004955,0.015484753,1.36102041,2.314229171,-6.383333542,-7.31452832,-4.285401787,-6.772558311,-6.881367477,-6.662811813,-6.716489619,-1.850630927 -1697,D113K,-0.023584661,-0.040841143,-0.031843672,0.011931752,-0.042644241,0.015565672,-0.015373182,-0.03179614,-0.019595556,-0.003621297,-0.078060988,-0.048979246,-0.014708097,0.031454282,-0.007590778,-0.033583311,-0.051705171,1.333009854,2.637029907,-3.780527765,-4.191460281,-3.862347183,-4.40760453,-4.224083595,-2.217143234,-3.985764686,-0.200880578 -1698,D113M,0.021792613,-0.121371565,-0.036394794,-0.03859152,-0.118088954,-0.022514115,0.043920486,-0.000335261,-0.012879528,-0.096462056,-0.146281073,-0.102279872,0.029490284,-0.065611123,-0.011571917,-0.201049046,-0.035128861,1.432427684,2.111935461,-8.529227145,-9.488900635,-7.537936844,-8.632344887,-10.36845863,-6.618494728,-8.063207869,-3.587826783 -1699,D113L,0.001230983,-0.082658381,-0.046631406,-0.023582636,-0.187793488,0.041656433,-0.003536653,0.005998619,-0.305185955,-0.058608405,-0.106708356,-0.105004095,0.011741284,0.025109294,-0.072274565,-0.212746322,-0.162840654,1.204637967,1.966333505,-7.675806174,-8.944348793,-6.529307388,-7.854026337,-9.80164724,-5.249701111,-7.382634317,-1.929697468 -1700,D113N,-0.003289525,-0.101987636,-0.087780813,-0.021207765,-0.052588139,0.023045961,-0.017137178,0.010558128,-0.333214679,-0.0445324,-0.159442872,-0.122642502,-0.052919123,0.016727427,-0.059142957,-0.058298314,-0.046877963,1.310227454,2.37781668,-3.901777501,-4.109251228,-2.600105591,-3.780799606,-5.20781601,-3.81091507,-4.942077351,-0.934336914 -1701,D113Q,-0.006251139,-0.082461597,-0.043712282,-0.026026505,-0.011883729,0.002028102,-0.046422335,0.033920057,-0.36185986,-0.06012322,-0.104799973,-0.091252154,0.003827591,-0.014747831,-0.037305178,-0.04847831,0.024710853,1.427294333,2.456213609,-4.271402892,-4.889651871,-2.603302948,-4.962453979,-5.307768578,-3.593837082,-4.501103549,-0.56071467 -1702,D113P,0.019705121,-0.051368187,-0.034524265,-0.030892901,-0.731114151,0.047504792,-0.006139037,0.045549279,-0.313745767,-0.046834407,-0.055901967,-0.094453634,0.025405105,-0.005969815,-0.055815987,-0.644509979,-0.817718323,0.835295556,1.442378991,-3.516033904,-3.202469048,-2.843122124,-4.8577006,-3.395413681,-3.281464066,-4.508889684,-0.621783594 -1703,D113S,0.011476431,-0.061166171,-0.043993411,-0.021342664,-0.023461345,-0.007596613,0.008574701,0.01437816,-0.245600265,-0.019292353,-0.103039989,-0.091465263,0.003478442,0.014786461,-0.057471789,-0.032472556,-0.014450133,1.262234571,2.455472153,-4.087348668,-5.014725502,-3.093674866,-4.142994453,-3.297485245,-4.887863274,-5.172966389,-0.123136978 -1704,D113R,-0.002822522,-0.117087183,-0.064919391,-0.049748511,-0.084542119,0.007624429,-0.040613293,0.03496825,-0.283104881,-0.052610377,-0.181563989,-0.110848504,-0.018990277,-0.017622124,-0.081874897,-0.087464097,-0.081620141,1.36733654,2.341892996,-5.511529041,-6.578319328,-3.334143402,-6.357819222,-6.250551086,-5.036812164,-5.879213936,-0.493689088 -1705,D113T,0.037015457,-0.037334526,-0.015502806,-0.00968365,0.022648909,0.000256886,0.009401691,0.064629222,-0.272393442,-0.023957035,-0.050712017,-0.069014374,0.038008762,0.009798003,-0.029165302,-0.008542009,0.053839826,1.270031354,2.57458469,-3.645084669,-3.959183289,-3.750410469,-4.157081734,-3.063069466,-3.295678391,-3.709804199,0.642943959 -1706,D113W,0.023645436,-0.100936033,-0.06457817,-0.046143992,-0.320755549,0.062341886,-0.013554651,0.060845522,-0.208275942,-0.073428917,-0.128443149,-0.126736601,-0.002419738,-0.069918535,-0.022369448,-0.328800126,-0.312710972,1.536014856,2.037876761,-9.657498454,-10.60896717,-6.868633202,-10.16631997,-11.59500535,-9.048566582,-8.826552328,-4.828149529 -1707,D113V,-0.041728481,-0.133429698,-0.030321518,-0.08259573,-0.086303752,0.087188424,-0.062374043,-0.021082919,-0.701191464,-0.096349271,-0.170510124,-0.075398084,0.014755049,-0.016954192,-0.148237267,-0.19391603,0.021308526,1.576861764,2.272458472,-7.041252718,-7.596784927,-6.49940107,-7.158358871,-8.094346764,-5.857371956,-6.436067333,-0.416098024 -1708,D113Y,-0.00024946,-0.077922253,0.015943823,0.015987679,-0.103097588,0.010656644,-0.022457045,0.021958125,-0.362178375,-0.002009696,-0.153834809,-0.024881884,0.056769529,0.072073572,-0.040098215,-0.084045504,-0.122149671,1.173055706,2.275185432,-9.596172444,-10.75324971,-7.775384155,-9.815136833,-11.01723132,-8.619860199,-8.349510638,-4.268056883 -1709,G114A,-0.052258946,0.017891372,-0.056769734,-0.167600109,-1.768156619,-0.043331769,-0.052199485,-0.052318406,0.018356639,-0.014443755,0.050226498,-0.022364987,-0.09117448,-0.029074517,-0.306125701,-1.770387729,-1.765925509,0.705964267,1.309951274,-3.599038327,-3.189959175,-2.807847427,-3.869261604,-4.346995987,-3.781127441,-5.396161454,-1.677790505 -1710,G114C,-0.01753952,-0.012402567,-0.040880867,-1.196267992,-1.693246199,-0.009382937,-0.007320245,-0.027758795,0.047249574,-0.071299301,0.046494167,0.014926887,-0.09668862,-0.917624222,-1.474911761,-1.948547727,-1.43794467,2.215907864,1.586400324,-9.824396623,-9.722391685,-8.862535187,-10.44423263,-11.15914683,-8.933676788,-9.920189241,-6.480357687 -1711,G114E,-0.081181612,-0.078714079,-0.109927164,-1.51613864,-2.497687707,-0.036786754,-0.036290341,-0.126072882,0.098856889,-0.062191986,-0.095236171,-0.085214153,-0.134640174,-1.409094138,-1.623183142,-2.101663324,-2.893712089,0.81416984,0.720916986,-4.581427092,-3.214432587,-4.154622986,-5.698572716,-5.564590851,-4.274916321,-6.04106102,-1.358848748 -1712,G114D,-0.017586551,-0.012473668,0.067514041,-0.909140344,-1.988670582,-0.059566248,-0.034223662,-0.000949439,0.053494856,-0.037151542,0.012204206,0.052720882,0.0823072,-0.836929585,-0.981351103,-1.982287447,-1.995053716,2.03843816,1.486619138,-6.461937589,-5.942688278,-4.596543701,-9.465972359,-6.397940033,-5.906543571,-4.948080191,-1.998619221 -1713,G114F,-0.010803282,-0.001301559,0.042601344,-0.212762102,-1.702591223,-0.022620475,0.001423519,-0.023030083,0.078107588,-0.066307588,0.063704471,0.019168739,0.066033949,-0.051352128,-0.374172075,-1.479285674,-1.925896772,0.71528473,1.323577597,-10.51306375,-8.568481827,-10.28085043,-11.22390545,-12.79444001,-9.697641022,-8.245593846,-4.852211453 -1714,G114I,0.029938626,-0.003227213,-0.884318388,-2.015982178,-2.694101807,-0.066959387,0.05657081,0.003306442,-0.119240834,-0.035717283,0.029262857,-0.745701877,-1.022934899,-1.64153018,-2.390434175,-2.572338531,-2.815865082,2.305264804,1.158789879,-8.525697266,-9.164081001,-8.069800964,-8.872663719,-9.044659287,-7.477281357,-8.444392314,-3.175788416 -1715,G114H,-0.062959066,-0.010459794,-0.016035178,-0.113281159,-1.947167109,-0.019273881,-0.024229606,-0.101688526,-0.112014792,-0.010647865,-0.010271722,-0.006851041,-0.025219315,-0.001212889,-0.225349429,-1.735283212,-2.159051006,0.750001987,1.311879328,-7.907985327,-8.842045929,-8.006818932,-8.539644455,-7.992439667,-6.158977654,-7.143346854,-3.157490128 -1716,G114K,-0.002736494,-0.01086061,-0.050661106,-0.523086564,-1.495484954,0.0274391,-0.010034594,0.004561606,-0.121603276,-0.078311099,0.05658988,-0.067371113,-0.033951099,-0.418326376,-0.627846752,-2.048104732,-0.942865175,1.586200202,1.355502272,-5.790717247,-4.818640686,-5.259508583,-7.473128418,-6.661064407,-4.741244141,-6.673126292,-1.832793388 -1717,G114M,0.084114106,0.00922786,0.052482184,-1.128752379,-2.691067714,-0.0551434,0.137125335,0.031102877,-0.063919886,-0.065867797,0.084323516,0.015414575,0.089549792,-0.914162311,-1.343342446,-2.710272088,-2.671863339,0.748960131,0.764557625,-9.253168694,-9.247984215,-8.733091805,-9.696616745,-10.34618143,-8.241969276,-8.345065635,-4.536344134 -1718,G114L,-0.050435,-0.062348978,-0.029288896,-1.528448965,-2.134513104,-0.011980735,-0.015110489,-0.085759511,-0.045746263,-0.06267444,-0.062023516,-0.017565782,-0.041012009,-1.24095101,-1.815946919,-2.411652614,-1.857373594,0.912563893,0.749804708,-8.105803751,-7.334414902,-7.262092949,-8.832146729,-9.777332535,-7.323031639,-7.795384578,-2.282779556 -1719,G114N,-0.057363309,0.032821028,0.000379228,-0.12269792,-1.979103618,-0.011775207,-0.059416271,-0.055310346,-0.015561775,0.033706608,0.031935447,0.017237217,-0.016478762,0.000132755,-0.245528594,-1.865174048,-2.093033188,0.670026017,1.302175855,-7.059820638,-7.249414291,-6.015740433,-9.91010611,-6.652781822,-5.471060532,-6.587049112,-1.966976726 -1720,G114Q,-0.045663144,0.001849678,-0.004160515,-1.274182827,-2.111681837,-0.025283927,-0.03021725,-0.061109038,-0.080086842,-0.004895248,0.008594604,0.007220096,-0.015541125,-1.134590635,-1.413775018,-2.354194526,-1.869169148,0.773722917,0.74414627,-4.872438417,-4.122978462,-4.391773872,-5.883182365,-5.946572395,-4.01768499,-5.373599185,-2.167280382 -1721,G114P,-0.046022219,0.004069263,0.001909876,-1.392465327,-2.048173868,-0.032586097,-0.043314727,-0.04872971,-0.081993107,-0.010364735,0.01850326,0.003494888,0.000324863,-1.126728501,-1.658202152,-2.251298384,-1.845049351,0.804588279,0.746157716,-6.513716069,-8.119616501,-4.904628983,-7.882971931,-7.314987122,-4.346375809,-6.422716517,-2.266757889 -1722,G114S,0.020665426,0.010883869,0.009627582,-0.062394297,-1.6983153,-0.039958661,0.029923099,0.011407753,-0.020543218,-0.055081258,0.076848995,-0.019789645,0.039044809,-0.045237844,-0.079550749,-1.733286452,-1.663344147,0.850554456,1.316947228,-5.314125014,-5.613813545,-4.482084282,-5.569885017,-5.866602806,-5.038239418,-5.312657173,-1.612134743 -1723,G114R,-0.019843435,-0.006754785,-0.111614522,-1.544478784,-2.508646797,-0.033358566,0.005624947,-0.045311816,-0.128755094,-0.011019129,-0.00249044,-0.097229252,-0.125999791,-1.326056756,-1.762900811,-2.351840621,-2.665452972,1.008379288,0.754877381,-5.330821971,-3.829508659,-6.295630104,-6.086318596,-5.552007248,-4.890645248,-6.531094649,-1.75195871 -1724,G114T,0.008407985,-0.023327468,0.016535778,-1.212874991,-1.887151206,-0.032864214,-0.016962848,0.033778817,-0.001734182,-0.061125349,0.014470413,0.012470194,0.020601362,-0.962133661,-1.46361632,-2.084827539,-1.689474872,2.133368712,1.476206813,-5.66976028,-5.413350845,-5.298682503,-5.947991348,-6.348618652,-5.340158051,-6.099292824,-0.945857586 -1725,G114W,-0.049827294,-0.029305054,-0.019590765,-1.155348911,-1.979103619,-0.029014825,-0.087860786,-0.011793802,-0.194742737,0.02102922,-0.079639328,-0.047566711,0.008385182,-0.831421254,-1.479276567,-1.849379781,-2.108827456,2.252496589,1.648863394,-10.8258831,-10.22910381,-9.719610458,-11.99006111,-12.54962327,-9.641016853,-9.526568028,-6.212724442 -1726,G114V,-0.033008155,-0.019527878,-0.205982146,-1.471611362,-2.478018652,0.003843141,0.020184786,-0.086201096,0.010862417,-0.043885529,0.004829773,-0.185896998,-0.226067293,-1.468541909,-1.474680815,-2.73141449,-2.224622813,1.21290972,0.768857499,-6.695513715,-7.410922089,-6.246939262,-7.145272713,-6.629886696,-6.044547813,-6.984001283,-2.2000305 -1727,G114Y,-0.044944248,0.027786258,-0.027859483,-0.243021703,-1.924038428,-0.00392352,-0.029596639,-0.060291856,-0.030569203,0.027105498,0.028467018,-0.006352711,-0.049366255,-0.062284167,-0.423759239,-2.015920049,-1.832156806,0.812527606,1.298921062,-9.847987239,-8.644797394,-10.15470536,-10.35064492,-11.81950072,-8.270287804,-7.785549904,-3.34927669 -1728,M115A,-0.056622202,-0.068531384,-0.041467528,-0.014917788,-1.660348986,0.004916551,-0.083502876,-0.029741528,0.000584594,-0.036433507,-0.100629261,-0.05160791,-0.031327145,0.03360058,-0.063436156,-1.496845816,-1.823852155,0.528379095,1.312400113,-7.657069528,-6.256641754,-9.884267883,-9.415676285,-6.702970993,-6.025790726,-5.331669625,-2.545473917 -1729,M115C,0.032658348,-0.147687105,-0.028378116,-0.039747957,-2.29634603,0.082799164,-0.072921218,0.138237914,-0.077880313,-0.115782178,-0.179592031,-0.002883751,-0.05387248,-0.025741882,-0.053754031,-1.702029922,-2.890662137,0.845256399,1.320221315,-11.94820169,-10.82647069,-13.7040987,-13.11784296,-12.2934129,-9.799183205,-7.311900375,-4.765233907 -1730,M115E,-0.077968902,-0.046352078,-0.181086297,-1.448695008,-2.747736235,0.019163441,-0.141224768,-0.014713035,0.265702033,0.000687946,-0.093392101,-0.040308689,-0.321863904,-1.227640216,-1.6697498,-2.510606212,-2.984866257,0.752470486,0.730520507,-11.95940157,-10.22333407,-13.17702732,-13.41546438,-11.32630573,-11.65487634,-7.936900214,-5.622652144 -1731,M115D,-0.038787071,-0.261846393,-1.326951676,-1.884608316,-2.42317742,-0.019872511,-0.040484376,-0.037089765,0.060155795,-0.12666251,-0.397030275,-1.181590038,-1.472313313,-1.794115463,-1.975101169,-2.158197204,-2.688157635,3.984665446,2.552604872,-15.14024923,-13.73035003,-16.68439781,-15.98276353,-15.43734532,-13.86638946,-9.962997699,-9.406221481 -1732,M115G,-0.006099182,-0.062980091,-0.387563766,-1.440625608,-3.110310358,0.039335314,-0.09790577,0.085707406,-0.076015051,-0.045485791,-0.080474391,-0.258669831,-0.5164577,-1.389641237,-1.491609978,-2.785505351,-3.435115365,1.414155449,0.829538387,-13.76476277,-12.63482731,-14.82893662,-15.19069814,-13.48751903,-12.68183276,-9.174082662,-7.131535802 -1733,M115F,-0.163045833,-0.040782916,-0.074139547,-1.506492191,-2.231619507,-0.032316376,-0.144913936,-0.181177729,0.0190297,0.024832119,-0.106397951,-0.02900914,-0.119269953,-1.390926572,-1.62205781,-2.031214725,-2.432024288,2.685988152,1.783490196,-7.682103101,-4.912254471,-10.81711462,-5.300588295,-9.395210251,-7.985347862,-4.142649948,-1.663375022 -1734,M115I,-0.008825115,-0.017988974,-0.033020477,0.013823225,-0.684160294,-0.027353373,-0.007512107,-0.010138123,0.104334031,-0.031112834,-0.004865114,-0.069775236,0.003734283,-0.053054419,0.080700868,-0.441446278,-0.92687431,1.357250895,1.793329789,-4.683843547,-3.39446933,-6.379566269,-4.616489922,-4.610214729,-4.418477486,-3.618939953,-1.341572605 -1735,M115H,-0.121289784,-0.13370729,-0.177391174,-1.510988192,-2.694574602,0.012189846,-0.131769805,-0.110809762,0.034709904,-0.09946688,-0.1679477,-0.167157203,-0.187625144,-1.424777251,-1.597199133,-2.265980248,-3.123168955,0.743968995,0.718601146,-12.74549892,-12.85342976,-15.10646534,-13.59494257,-11.84877366,-10.32388329,-7.183928192,-4.630262733 -1736,M115K,-0.137168453,-0.075789798,-0.077706493,-1.90351206,-1.942081163,0.040139334,-0.082431539,-0.191905367,0.140763297,-0.063544973,-0.088034622,-0.054065453,-0.101347533,-1.302218217,-2.504805902,-1.967329954,-1.916832372,2.815642752,1.931521494,-11.82922132,-11.58241544,-12.67465241,-13.0703722,-11.3271446,-10.49152195,-7.685133571,-5.080711508 -1737,M115L,-0.124186365,-0.098778892,-0.045003608,-0.040834803,-0.112630744,0.001252237,-0.119539652,-0.128833077,0.050102233,-0.068261582,-0.129296201,-0.075643276,-0.014363939,-0.035239433,-0.046430173,-0.083377853,-0.141883635,1.363850935,2.355303888,-3.897132072,-2.424484856,-4.911321648,-3.267854301,-5.733329231,-3.148670326,-3.94103758,-0.432441207 -1738,M115N,-0.042723176,-0.041464127,-0.045461202,-1.565522461,-2.30546101,0.039907677,-0.055279293,-0.030167058,0.146515626,-0.046895215,-0.036033039,-0.060710157,-0.030212246,-1.51353474,-1.617510182,-2.405294109,-2.205627911,0.803129892,0.711004928,-14.7025651,-14.01788326,-15.68131265,-15.77742808,-14.01445329,-14.02174821,-9.962997699,-9.406221483 -1739,M115Q,-0.16367383,-0.084851946,-0.008220067,-0.052392805,-1.057211717,0.054061539,-0.185895163,-0.141452496,0.06405667,-0.016418944,-0.153284947,0.013923461,-0.030363595,-0.028140959,-0.076644651,-0.765696958,-1.348726476,0.834080863,1.412129703,-9.32518147,-8.043374817,-11.15993693,-10.32548768,-8.300877731,-8.796230194,-6.214519808,-4.794254427 -1740,M115P,-0.076724651,-0.156759658,-1.372273813,-1.943167901,-2.825104778,0.016328867,-0.068898961,-0.08455034,0.03004814,-0.111039848,-0.202479467,-1.413232825,-1.3313148,-1.848113163,-2.038222638,-2.500990443,-3.149219113,4.1214818,2.548249186,-10.77149086,-10.00011649,-12.61098505,-12.03655227,-10.74829528,-8.461505203,-6.08220368,-3.41587074 -1741,M115S,-0.029678192,-0.07116084,-0.03462944,-0.713154795,-2.116785912,0.03058248,-0.086401727,0.027045343,0.01516303,-0.040015366,-0.102306313,-0.082809325,0.013550446,-0.346626666,-1.079682923,-1.838772443,-2.39479938,1.52920832,1.387411341,-11.30751804,-10.53424852,-12.3439129,-12.62952574,-10.67317348,-10.35672956,-7.185035872,-4.660588547 -1742,M115R,-0.138576712,-0.086263148,-0.064304828,-0.378250543,-1.967259332,0.020707342,-0.154541892,-0.122611531,-0.000198898,-0.049448268,-0.123078027,-0.054584279,-0.074025376,-0.195368059,-0.561133027,-1.751659306,-2.182859357,1.246257237,1.35406467,-9.835787199,-9.539482368,-12.11038084,-11.22650954,-8.888504303,-7.414058945,-6.487128913,-3.452822007 -1743,M115T,-0.106577522,-0.055964106,-0.016948808,-1.198464385,-1.986188766,0.032687248,-0.110913919,-0.102241124,0.047646273,-0.038899405,-0.073028807,-0.041890821,0.007993205,-0.873435705,-1.523493065,-2.00343424,-1.968943291,2.182368381,1.550180177,-9.322909662,-9.246922295,-9.679179863,-11.04959677,-8.203036575,-8.435812805,-6.546711579,-2.510821502 -1744,M115W,-0.174560106,-0.27625793,-1.398762983,-2.184385601,-2.906943098,0.025950839,-0.197031529,-0.152088683,0.11309187,-0.124517879,-0.427997981,-1.352725689,-1.444800277,-1.898304324,-2.470466878,-3.107484106,-2.706402089,2.550331128,1.055091931,-12.7827295,-11.65941707,-15.46047152,-12.52841714,-14.11321976,-10.15212202,-7.098840595,-4.05813142 -1745,M115V,-0.134707651,-0.058465645,-0.089823879,-0.039572448,-1.68219455,0.064251258,-0.126465853,-0.142949448,0.0190297,-0.024681179,-0.09225011,-0.09606245,-0.083585307,-0.021666373,-0.057478522,-1.589698152,-1.774690947,0.811550422,1.325087332,-6.050000311,-5.089568939,-6.702029602,-5.394023697,-7.138596581,-5.925782738,-4.492999433,-1.520890789 -1746,M115Y,-0.089597318,-0.035835628,0.006440157,-1.586716151,-2.522258013,0.017847125,-0.099426233,-0.079768403,-0.027502625,-0.050612729,-0.021058527,-0.01453207,0.027412383,-1.263133253,-1.910299048,-2.421160512,-2.623355514,0.785261256,0.731521154,-11.77371922,-10.10593707,-15.19355828,-10.76927687,-12.00707725,-10.79274661,-5.849446893,-1.615744938 -1747,T116A,0.096394739,-0.012390102,-0.042528551,-0.001876493,-1.378888234,0.032008052,0.065276668,0.12751281,-0.151413632,0.078066843,-0.102847047,-0.057643338,-0.027413763,0.051185565,-0.05493855,-1.044282614,-1.713493853,0.780854477,1.360647974,-4.614339275,-4.161985672,-4.621226746,-4.153857567,-5.838130638,-4.29649575,-5.179335489,-2.372269727 -1748,T116C,-0.086447982,0.020035095,-0.029195316,-0.025121597,-1.569669022,0.095483117,-0.107448004,-0.065447959,-0.08100631,0.104092427,-0.064022237,-0.000669527,-0.057721105,0.097499048,-0.147742242,-1.455091295,-1.684246748,0.533904654,1.31616875,-7.801314934,-7.021524559,-7.528456032,-7.55381443,-9.330720345,-7.572059303,-8.612227385,-6.810902485 -1749,T116E,0.069504655,0.066137848,0.027460795,0.020299755,-0.001675007,0.023687633,0.02916211,0.1098472,0.001344982,0.085237057,0.047038639,0.030376475,0.024545114,0.010780007,0.029819503,0.009128111,-0.012478125,1.671448915,3.643209181,-6.229341185,-5.011655403,-5.123377747,-6.718684509,-7.836104523,-6.456883743,-6.452198833,-4.01517444 -1750,T116D,-0.030855104,-0.029356323,0.022589177,-0.016174991,-0.767261411,0.085524086,-0.001411025,-0.060299182,-0.007220096,0.032587367,-0.091300013,0.01243301,0.032745343,-0.032087354,-0.000262627,-0.569440999,-0.965081822,0.795502696,1.448333978,-5.397210226,-4.51030629,-3.894584938,-6.098363991,-5.675298401,-6.807497513,-6.857411849,-3.441201631 -1751,T116G,-0.037451251,0.003788104,-0.025471308,-1.057255801,-1.92948211,0.067372468,0.007750278,-0.08265278,-0.142067122,0.04611395,-0.038537743,-0.017096333,-0.033846282,-0.798570221,-1.31594138,-2.207586762,-1.651377457,1.883066057,1.36353168,-7.436768065,-6.649058983,-6.841107506,-7.244508652,-8.544755043,-7.904410141,-7.329533248,-5.764104996 -1752,T116F,-0.024081097,-0.01206305,0.008642252,-1.341195415,-2.045538289,0.065804654,-0.021759234,-0.026402959,-0.089961153,0.038742007,-0.062868107,-0.022084492,0.039368995,-0.650529216,-2.031861613,-1.85135772,-2.239718857,1.907197123,1.487728217,-9.036252298,-7.680810829,-8.275699295,-8.774218239,-11.28936111,-9.16117202,-8.766760603,-7.164629084 -1753,T116I,-0.029547712,-0.036664545,-0.064523849,-0.068939464,-1.547883899,0.077119354,-0.011940482,-0.047154941,-0.029644942,-0.002965925,-0.070363164,-0.063844135,-0.065203562,0.028888379,-0.166767306,-1.535769004,-1.559998793,0.62964893,1.315410619,-7.159902267,-6.423829994,-7.775798553,-6.781250664,-8.418593834,-6.400038292,-7.352200868,-5.955867113 -1754,T116H,0.02698576,-0.01569922,0.029027382,-1.036932022,-2.348609979,0.011537435,0.040118252,0.013853267,-0.026944657,-0.000513047,-0.030885392,0.026332495,0.031722269,-0.664338379,-1.409525665,-2.380867044,-2.316352914,1.669408642,1.274405174,-8.265350034,-7.846726135,-7.334351784,-8.873594246,-8.771982643,-8.50009536,-9.770391327,-9.847493683 -1755,T116K,-0.026848944,-0.03467044,-0.029296088,0.011737577,-1.586312554,0.085532432,-0.021459618,-0.03223827,0.101924373,0.052448811,-0.12178969,-0.01356123,-0.045030945,0.073327867,-0.049852714,-1.451992006,-1.720633101,0.572293954,1.315783721,-4.458234241,-3.681269638,-3.994954529,-4.943261818,-5.849586578,-3.82209864,-5.626272579,-3.553647011 -1756,T116M,0.026839618,0.001257632,-0.00284641,0.008295448,-1.060159582,0.075087842,0.015370074,0.038309162,0.09793389,0.029434847,-0.026919584,0.001354928,-0.007047748,0.015276936,0.001313959,-0.822580349,-1.297738815,0.680625784,1.371287564,-7.733835994,-6.800856728,-7.749093094,-7.481633636,-9.084618591,-7.552977921,-8.106534065,-6.655915323 -1757,T116L,0.020980627,0.015232159,0.009699732,0.008278787,-0.831106691,0.066479028,0.032834317,0.009126937,-0.006812116,0.047584838,-0.017120521,0.014663819,0.004735645,0.022185026,-0.005627452,-0.658472336,-1.003741046,1.097736136,1.538400506,-6.853724619,-5.844785706,-6.786302765,-6.986213089,-8.223928528,-6.427393005,-7.641911601,-5.552171553 -1758,T116N,-0.047183178,0.021534895,0.014729906,0.039494819,-0.573047728,0.090701393,-0.050073584,-0.044292771,0.001700524,0.083574623,-0.040504833,0.014603877,0.014855934,0.096196526,-0.017206889,-0.390212785,-0.75588267,0.482376413,1.412208848,-4.003851917,-3.77908374,-2.76343399,-5.301901199,-4.235599068,-3.939241585,-4.742965533,-3.955874279 -1759,T116Q,0.085722727,-0.005381476,-0.001254338,0.01740643,-0.500701472,0.040098109,0.076431412,0.095014042,0.010702509,0.016964311,-0.027727262,-0.027338078,0.024829403,-0.003220111,0.03803297,-0.33382594,-0.667577003,1.339213689,1.879034207,-5.649044252,-4.954283035,-5.140034462,-6.070448761,-6.811470032,-5.26898497,-6.587596811,-4.544357019 -1760,T116P,-0.046010731,-0.037404854,0.007097428,0.010524426,-1.676214293,0.034947385,-0.05518299,-0.036838472,0.058135102,0.026031924,-0.100841632,0.024999426,-0.010804571,0.085652293,-0.064603441,-1.510649737,-1.841778848,0.462059377,1.309133238,-4.195094287,-3.356011261,-4.115027458,-4.071187141,-6.431942627,-3.001302948,-5.99379716,-1.898445868 -1761,T116S,0.016682239,-0.007373946,-0.031960188,-0.02026366,-0.073522367,-0.025618872,0.014746663,0.018617814,0.030712057,0.019879999,-0.03462789,-0.028017977,-0.035902398,-0.004516592,-0.036010727,-0.009275676,-0.137769058,1.171406769,2.578300048,-0.972463873,-0.810954742,-0.307503822,-1.231742119,-1.902097954,-0.610020729,-2.654468962,-0.478462339 -1762,T116R,0.006765715,-0.012477792,-0.055089574,-0.02870607,-2.094839733,0.055840661,0.021516829,-0.0079854,-0.056438119,0.019530131,-0.044485714,-0.05862743,-0.051551717,0.018878483,-0.076290622,-1.778336782,-2.411342683,0.622077378,1.304595661,-3.691119621,-3.88523246,-3.152838539,-4.065354774,-3.446243156,-3.905929176,-4.744740371,-3.333135843 -1763,T116W,0.00755318,-0.008474647,-0.956158623,-1.884637119,-2.491227844,0.044729514,0.01371971,0.001386649,-0.028409395,0.026117757,-0.04306705,-0.864858268,-1.047458977,-1.706536059,-2.062738179,-2.092071505,-2.890384182,3.521989718,2.239853713,-9.128722888,-7.850205513,-8.478898636,-8.918624649,-10.97518143,-9.420704216,-9.521499716,-8.649720343 -1764,T116V,-0.003884605,0.016952352,-0.004320679,0.021454367,-1.539845587,0.061938764,-0.009394143,0.001624934,-0.131484986,0.066963829,-0.033059126,-0.00981907,0.001177713,0.047698083,-0.00478935,-1.502320952,-1.577370222,0.13344225,1.300237148,-8.139961909,-7.088425179,-8.937940758,-7.674339752,-9.430620529,-7.56848333,-8.819686118,-7.223782664 -1765,T116Y,-0.060882052,-0.039298247,-0.01677034,-0.728765137,-2.162579891,0.112041439,-0.027246054,-0.094518049,-0.06344302,0.025227444,-0.103823937,-0.006719983,-0.026820696,-0.300444298,-1.157085975,-2.250251174,-2.074908608,1.319165487,1.294205984,-8.985182095,-7.471534233,-8.631373306,-8.698054375,-11.08645425,-9.038494308,-9.05453873,-7.473254964 -1766,V117A,-0.250511096,-0.025107282,0.019636518,-1.213244232,-1.947442241,0.024692884,-0.007830032,-0.49319216,-0.022486148,0.045369986,-0.095584549,0.015459294,0.023813741,-0.812535402,-1.613953062,-1.979038093,-1.915846389,2.007254243,1.478538322,-6.256039713,-5.98053302,-4.507085594,-7.746361702,-8.587839943,-4.458378304,-5.207618673,-1.847820448 -1767,V117C,-0.226375298,-0.006504277,0.032854397,-1.201150381,-2.283712065,0.084123712,-0.012151081,-0.440599515,-0.180456064,0.000650069,-0.013658622,0.053712199,0.011996595,-1.035231867,-1.367068895,-1.763164721,-2.804259409,2.804048289,2.085719938,-10.95268839,-10.00516948,-8.347687782,-14.83530769,-12.09111189,-9.484165131,-8.381039763,-6.306644863 -1768,V117E,-0.276191234,-0.007437206,-0.525781157,-1.620442323,-2.565433678,-0.038608921,0.002562217,-0.554944684,-0.015794267,-0.002937629,-0.011936782,-0.196379794,-0.855182519,-1.384373259,-1.856511387,-2.179588135,-2.95127922,2.433421696,1.519822977,-11.76438717,-11.25055074,-8.804499214,-14.84908593,-13.84348036,-10.07431959,-9.511233958,-9.330018295 -1769,V117D,-0.307054464,-0.916290834,-1.64686067,-2.214708265,-2.88154837,-0.041883015,-0.025988182,-0.588120746,0.036429266,-0.934588237,-0.89799343,-1.774330922,-1.519390417,-1.920931702,-2.508484828,-2.858814081,-2.904282658,3.371710382,1.384173742,-12.07038595,-11.42261776,-8.848602249,-15.74962344,-13.75812628,-10.57296002,-9.511233958,-9.330018295 -1770,V117G,-0.259487311,-0.033888666,-1.108468384,-2.010513529,-2.630401382,0.039384244,-0.061763724,-0.457210897,-0.003895044,-0.034730723,-0.033046608,-1.170246244,-1.046690524,-1.895841711,-2.125185346,-2.694062097,-2.566740666,2.450018708,1.058305433,-9.32960853,-9.608780075,-6.608836143,-12.10435221,-9.609064232,-8.717009987,-6.628344824,-4.894434212 -1771,V117F,-0.188603312,-0.01185563,-0.03228895,-1.048876452,-1.859549574,0.089330663,0.041944521,-0.419151145,-0.052388069,-0.000779093,-0.022932167,-0.063102807,-0.001475092,-0.694003426,-1.403749478,-1.794613104,-1.924486044,2.064150368,1.576902693,-7.688964813,-7.261733582,-4.750369385,-11.56991686,-7.709894913,-7.152909325,-6.167704493,-3.241670036 -1772,V117I,-0.264380752,-0.02920765,0.056501333,-0.049630351,0.022859979,-0.009719234,-0.065094785,-0.463666719,-0.06694679,0.027903845,-0.086319145,0.065933766,0.047068899,-0.010976191,-0.08828451,0.076875851,-0.031155894,1.114094106,2.718588556,-1.766500677,-1.233026207,-0.773263023,-2.908008606,-2.447022835,-1.471182716,-3.072235679,-0.578043005 -1773,V117H,-0.289175098,-0.026007544,-0.250962872,-1.640489799,-2.170829267,0.028951614,-0.064845118,-0.513505078,0.142667504,-0.025152627,-0.02686246,-0.127544045,-0.374381698,-1.447331093,-1.833648504,-2.28830346,-2.053355074,0.710398312,0.708163689,-12.16490238,-11.27475385,-8.348230751,-18.58385271,-12.89511638,-9.722558228,-8.435883383,-6.316306537 -1774,V117K,-0.314088284,-0.094016622,-1.227326892,-1.775715455,-2.743585555,0.048729118,-0.011429462,-0.616747106,-0.367976785,-0.067092974,-0.12094027,-1.115719431,-1.338934353,-1.767470189,-1.78396072,-2.705352569,-2.78181854,2.569394654,1.186123224,-11.77331802,-11.00674554,-9.195935226,-15.6438784,-13.41667705,-9.603353874,-8.795120501,-7.59899137 -1775,V117M,-0.242216954,-0.06286596,-0.036932776,0.048201832,-0.048577408,-0.028879733,-0.011139061,-0.473294847,-0.284639579,-0.027378655,-0.098353264,-0.087616954,0.013751403,0.019427763,0.076975901,-0.081076079,-0.016078737,1.435503918,2.458437854,-4.363642732,-4.042321251,-3.356096565,-5.572183731,-4.242629311,-4.604982803,-5.326074086,-3.197302179 -1776,V117L,-0.238267232,-0.021159241,0.024611372,0.01605092,-0.058099032,-0.020830975,-0.041196216,-0.435338248,-0.117876882,0.043942275,-0.086260757,0.049325767,-0.000103023,0.047415753,-0.015313914,-0.010972009,-0.105226054,1.185372534,2.546179649,-1.536661563,-0.507659531,-0.864835884,-2.666406036,-2.114310829,-1.530095535,-2.565617873,0.221344319 -1777,V117N,-0.323625866,-0.046714637,-0.017821474,-1.321835129,-2.185462835,0.082775303,-0.039109859,-0.608141872,-0.460730839,0.042462565,-0.135891839,0.079938528,-0.115581475,-1.165148653,-1.478521605,-2.144423718,-2.226501952,0.293690638,0.703575332,-10.22056292,-9.215030731,-6.933738625,-14.49957343,-11.64967973,-8.804792068,-7.004085511,-4.725911779 -1778,V117Q,-0.374484991,-0.113015164,-0.043925761,-1.51255185,-2.298832998,0.01228646,-0.119308091,-0.62966189,-0.140178703,-0.070041534,-0.155988793,-0.056011888,-0.031839634,-1.254506941,-1.770596758,-2.607362668,-1.990303328,0.954681013,0.753963793,-10.34271522,-9.846376663,-8.172675468,-13.49672191,-11.7785806,-8.419221481,-8.082229509,-5.919210967 -1779,V117P,-0.282371759,-0.055102391,-0.023587482,-1.131230533,-1.988141729,0.021275363,-0.052658825,-0.512084693,0.04635364,-0.016095122,-0.094109659,-0.02752038,-0.019654583,-0.719092667,-1.543368399,-1.945114552,-2.031168906,1.878424839,1.435540398,-8.74989317,-9.146503532,-6.739240585,-10.21970612,-9.334212524,-8.309803085,-5.847463461,-4.28899689 -1780,V117S,-0.348059451,-0.035935456,-0.28899662,-1.568728596,-2.625799367,0.023947219,-0.141448093,-0.554670808,0.080372727,0.00389917,-0.075770082,-0.172310849,-0.405682391,-1.435725411,-1.70173178,-2.43806578,-2.813532953,1.090847166,0.750603818,-10.37309728,-8.974818558,-7.740371674,-14.07290837,-11.35054575,-9.726842072,-7.170111636,-5.234485494 -1781,V117R,-0.243611801,-0.116422603,-1.302567087,-2.105439961,-2.851083992,0.055374351,-0.049218023,-0.438005578,-0.10942657,-0.013825151,-0.219020054,-1.261835015,-1.343299158,-1.866251895,-2.344628026,-2.563802119,-3.138365864,2.719713343,1.25561952,-10.26244764,-9.830498306,-8.016289116,-14.15769828,-11.63069751,-7.67705497,-6.915723326,-4.487000931 -1782,V117T,-0.250115225,-0.029834128,0.012580353,-0.010530529,-1.370634622,0.014738635,-0.063904121,-0.436326329,-0.048098706,-0.018617994,-0.041050261,-0.005479869,0.030640574,-0.03461359,0.013552532,-1.218751656,-1.522517588,0.791332732,1.346513606,-7.932260651,-7.3525056,-6.132693611,-9.979522179,-9.792545494,-6.404036369,-5.806539921,-4.179871568 -1783,V117W,-0.255943221,-0.07443053,-1.351495715,-2.25605126,-2.962481988,0.082008652,-0.035083687,-0.476802755,0.022862883,-0.018388764,-0.130472295,-1.337376396,-1.365615033,-1.961098431,-2.551004089,-2.978162057,-2.946801918,0.676915488,0.066440147,-6.81026353,-5.538782013,-5.907137848,-10.82712364,-6.731381027,-5.04689312,-5.245307703,-2.573251214 -1784,V117Y,-0.341380559,0.018609144,-0.034203576,-1.394499607,-2.304200425,0.01260048,-0.125092714,-0.557668403,-0.140178703,0.030374065,0.006844223,0.082006953,-0.150414105,-1.287463246,-1.501535968,-2.057854539,-2.550546311,2.363392742,1.566767692,-8.398606474,-8.399777885,-4.581695366,-13.35265824,-8.276664719,-7.38223616,-5.916726252,-2.124789941 -1785,R118A,0.086174337,0.036147797,0.054661962,0.036302631,0.057780066,-0.030544938,0.082391506,0.089957168,-0.113598084,0.005040887,0.067254706,0.049513357,0.059810566,-0.018988636,0.091593898,0.025219404,0.090340727,1.129499537,2.631264114,2.608249808,2.067431641,1.33406282,4.326858444,2.398596985,2.914299149,0.053316386,-0.303358467 -1786,R118C,0.182783302,0.082868515,0.089045377,0.082955726,0.022429659,0.06474849,0.201817594,0.163749009,-0.062667992,0.058436288,0.107300741,0.066608316,0.111482437,0.047041678,0.118869773,0.006497962,0.038361356,1.362070184,2.808701961,-4.961308159,-5.524642593,-4.908453377,-5.097004501,-4.093757217,-5.182683105,-6.382058056,-7.535893983 -1787,R118E,0.026017109,0.07171736,0.039529654,0.012008209,0.049050117,0.012406799,0.059711986,-0.007677769,-0.046873724,0.036373948,0.107060771,0.009189876,0.069869431,-0.040645994,0.064662411,0.022645952,0.075454281,1.319069709,2.77049399,-0.060092778,-0.681121918,-0.434588867,0.004133987,0.238823456,0.572289452,-1.782542163,-1.148032941 -1788,R118D,0.02625042,-0.008629554,0.027487298,-0.005125526,0.030534581,-0.018908223,0.059340779,-0.00683994,0.481400053,0.029966262,-0.047225369,0.04894379,0.006030805,-0.004127966,-0.006123085,-0.015306892,0.076376053,1.305479997,2.628227821,-0.851754948,-1.174133881,-1.29758036,-0.946357597,-0.152816086,-0.687886818,-1.49805114,-1.726436461 -1789,R118G,-0.016353398,0.007237049,0.016317244,0.001971505,0.015036122,0.029744834,0.04553641,-0.078243206,-0.036100364,0.017650653,-0.003176556,0.006644602,0.025989886,-0.010657668,0.014600678,0.020148635,0.009923609,1.257875546,2.740139213,2.42835004,1.753671661,1.117619255,3.419369751,3.014228668,2.836860863,1.358974398,-1.007176965 -1790,R118F,-0.010086077,-0.008922288,0.031678691,-0.00084538,-0.006853186,-0.046255189,0.017741545,-0.037913699,0.073475823,-0.018917714,0.001073139,0.026057801,0.03729958,-0.018401478,0.016710718,-0.029195698,0.015489326,1.261964956,2.478207252,-2.652566455,-3.590400818,-2.510470673,-4.472113533,-0.88971225,-1.800135002,-2.979444554,-3.623692675 -1791,R118I,-0.008065667,0.041606408,0.043735705,0.043729638,-0.472002342,0.087401726,0.053570593,-0.069701927,-0.067414427,0.049823183,0.033389632,0.064504984,0.022966425,0.039629254,0.047830021,-0.335535374,-0.608469309,0.9722927,1.639672269,-3.630767558,-4.32337056,-2.568267677,-3.772211945,-2.818514839,-4.671472771,-4.073915932,-3.211824015 -1792,R118H,0.06998799,0.02950257,0.07556677,-0.020113119,0.046338758,-0.039179097,0.067571818,0.072404162,-0.000366107,-0.000801822,0.059806961,0.018867698,0.132265842,-0.041561794,0.001335557,-0.022527103,0.115204618,1.276755325,2.520657352,-1.779945047,-3.265339722,-2.004851181,-1.985595322,-1.073590446,-0.570348564,-2.897583917,-2.870426506 -1793,R118K,-0.124317671,-0.055915783,0.01440222,0.032936827,-0.042341403,-0.053301075,-0.038321845,-0.210313497,-0.193210606,-0.058148768,-0.053682797,0.031089862,-0.002285422,0.062878735,0.002994919,-0.021870465,-0.06281234,1.199371564,2.585908336,-1.227413821,-2.028689102,-1.385240013,-0.904828201,-1.060304016,-0.758007774,-1.573049189,-1.262806123 -1794,R118M,-0.020730537,-0.009793038,-0.012474862,-0.016744207,-0.024256937,0.019387667,0.036246334,-0.077707407,-0.036339053,-0.03359527,0.014009194,-0.03632429,0.011374566,-0.047594451,0.014106038,-0.042827216,-0.005686658,1.321427578,2.414619047,-4.22474585,-4.225494652,-2.982794655,-4.803388603,-3.74320961,-5.368841728,-3.807379678,-3.777869985 -1795,R118L,0.036529635,0.028522918,0.07093257,0.03463397,-0.023411341,-0.023285624,0.067052425,0.006006844,-0.088475255,0.008423469,0.048622366,0.029636288,0.112228852,-0.002828081,0.07209602,-0.03419249,-0.012630191,1.063767873,2.354444695,-2.990524242,-4.022805885,-0.744396683,-3.386797646,-2.213631485,-4.58498951,-2.909018028,-1.461244213 -1796,R118N,-0.018257246,0.048629175,0.052406513,0.042307846,0.040624438,-0.046720335,0.026298151,-0.062812643,-0.098383544,0.066950968,0.030307381,0.104571415,0.00024161,0.023372939,0.061242752,0.052310998,0.028937877,1.162116382,2.789158065,-1.870366907,-2.683146286,-2.278595535,-1.804548996,-1.493231323,-1.092312393,-3.024305013,-3.58612226 -1797,R118Q,0.055458725,0.033137688,0.110430601,0.089627048,0.110618312,-0.101266697,0.055743762,0.055173687,0.036947915,0.045067875,0.0212075,0.107073451,0.113787751,0.054092652,0.125161444,0.060884887,0.160351736,1.105709139,2.810446524,-1.307802061,-1.86728627,-0.799366371,-1.824746284,-2.057256424,0.009645042,-2.338629866,-2.091168542 -1798,R118P,0.03162797,0.013754581,0.04145012,-0.475285336,-1.724867907,0.029083611,0.086816598,-0.023560659,-0.009085164,0.026438304,0.001070857,0.046332281,0.036567958,-0.211410904,-0.739159768,-1.857268035,-1.592467778,1.1428302,1.328309473,-4.2043416,-4.525827843,-4.360792603,-3.671159897,-4.022478142,-4.441449516,-4.718240439,-5.323603949 -1799,R118S,0.063759247,0.043443772,0.04895046,0.063100099,0.090750713,-0.004211205,0.114919641,0.012598852,0.078380518,0.015771137,0.071116407,0.045178804,0.052722116,0.037998827,0.088201371,0.031807283,0.149694143,1.069916017,2.663732896,1.748565997,1.321200928,0.540397499,2.547294426,1.931762077,2.402175056,-0.376137692,-1.209918886 -1800,R118T,0.053708148,0.019056112,0.018983507,0.02255016,0.015904985,0.003673225,0.098374047,0.009042248,-0.131125372,-0.001719595,0.039831819,0.015743663,0.02222335,-0.009028314,0.054128633,-0.020515891,0.05232586,1.160497553,2.437837684,-1.062213403,-1.122592728,-1.509501381,-0.441777153,-1.162814873,-1.074380882,-2.858373821,-3.2849989 -1801,R118W,0.017369632,0.076466821,0.057532255,0.069627325,0.068141592,0.009984405,0.083503656,-0.048764393,0.061505468,0.044902379,0.108031262,0.019072551,0.095991958,0.029530175,0.109724474,0.029403334,0.10687985,1.070977887,2.607428009,-4.707745654,-5.198376587,-3.869727547,-6.208966713,-3.738145645,-4.52351178,-4.62424297,-4.591170079 -1802,R118V,0.019249195,0.025173664,0.044162056,0.018263055,-0.175151046,0.031916276,0.054700098,-0.016201708,-0.011515469,-0.011926443,0.062273771,0.066105504,0.022218608,-0.006275302,0.042801411,-0.178853345,-0.171448747,1.321244515,2.083570169,-3.001961591,-3.718892128,-2.92480423,-2.41732473,-2.517649147,-3.431137718,-3.24651071,-4.011718749 -1803,R118Y,0.105373281,0.040647812,0.067758179,-0.006526441,0.022056821,0.012739139,0.161771559,0.048975002,-0.041478693,-0.042281124,0.123576747,0.000468971,0.135047387,-0.034902183,0.021849301,-0.068042977,0.112156619,1.392197644,2.433282774,-2.341448868,-3.676400009,-2.48361554,-4.356644783,-0.863798401,-0.326785606,-3.560906808,-2.484003953 -1804,E119A,0.027917422,-0.014252553,-0.041742661,0.020854251,-0.286135695,0.061169193,0.058886846,-0.003052003,0.090992207,0.018368618,-0.046873724,0.055265518,-0.13875084,0.018443246,0.023265255,-0.279481195,-0.292790195,1.640244272,2.228530588,-1.68036879,-1.041278931,-1.861974503,-2.003862015,-1.675052582,-1.819675919,-2.930924778,-1.668735283 -1805,E119C,0.063467143,-0.055601904,0.030413899,-0.961872186,-2.128841353,0.135294278,0.059121452,0.067812834,0.302996022,0.030125346,-0.141329153,0.107988897,-0.047161099,-0.635704107,-1.288040265,-1.999425346,-2.258257359,1.791020157,1.409306824,-8.461060606,-7.017796204,-7.894433495,-9.320650803,-8.619765862,-9.45265667,-8.4950091,-6.548781088 -1806,E119D,-0.02953949,0.015749702,0.004683221,0.050086508,0.050682024,-0.056811682,0.018353202,-0.077432181,-0.11676206,0.120156541,-0.088657138,0.102986998,-0.093620557,0.098287928,0.001885088,0.028303368,0.073060679,1.106009441,2.723212628,-1.697410106,-1.166853638,-1.590391258,-1.451865479,-2.279337151,-1.998603004,-3.590373606,-0.287518404 -1807,E119G,0.088821998,-0.020923239,-0.041675409,0.0279152,-0.211259948,0.061434353,0.083606703,0.094037292,-0.07234292,0.015106902,-0.056953379,0.047360835,-0.130711652,0.035709092,0.020121307,-0.174714107,-0.247805789,1.187118251,2.014754366,-3.717300769,-3.15910347,-3.364646149,-4.224170113,-3.684490883,-4.154093231,-4.844490384,-3.795812327 -1808,E119F,-0.116016302,-0.046292864,-1.04424611,-2.17094009,-2.810730425,0.090127437,0.024359346,-0.25639195,0.040553398,-0.012066131,-0.080519597,-0.872675434,-1.215816785,-1.755836373,-2.586043806,-2.629471381,-2.991989469,2.308789484,1.091189955,-8.788129854,-7.234076248,-6.9253349,-10.21703087,-8.918424095,-10.64578316,-7.264344361,-4.629417234 -1809,E119I,0.022108467,-0.590078825,-1.451871496,-1.883245091,-2.332929806,0.035654626,0.078463997,-0.034247063,0.003037037,-0.56794674,-0.612210909,-1.49651819,-1.407224802,-1.892128346,-1.874361836,-2.862673367,-1.803186245,2.972448482,1.26469962,-8.443008742,-6.503017258,-7.274406425,-9.010527184,-8.441376053,-10.98571679,-7.693987913,-5.58848318 -1810,E119H,-0.049829863,-0.073091612,-0.035737184,0.007486847,-0.909007435,0.086480449,-0.021189299,-0.078470427,0.090992207,0.011352828,-0.157536051,0.057662512,-0.129136879,0.01457309,0.000400604,-0.737225298,-1.080789571,0.756804599,1.400119071,-6.718770551,-6.011270592,-6.575578011,-6.395580864,-6.847009132,-7.764414154,-6.481936295,-4.900684251 -1811,E119K,-0.068320259,-0.010494547,-0.028575661,0.001772193,-1.414133549,0.086077034,0.063386979,-0.200027497,-0.063909753,0.053256934,-0.074246028,0.060516378,-0.1176677,0.103258935,-0.099714549,-1.610272919,-1.217994179,0.428811974,1.304524708,-4.236303406,-3.520186157,-4.116255905,-4.384792305,-3.820021767,-5.340260895,-5.111732891,-2.645466687 -1812,E119M,0.07336774,0.007963481,0.047043215,0.044637252,-1.63992501,0.022757913,0.020850139,0.125885341,-0.328727576,0.09085733,-0.074930369,0.106228434,-0.012142004,0.024485497,0.064789006,-1.695655313,-1.584194706,0.232308177,1.297717247,-7.126239142,-5.726748512,-6.319437027,-8.479501549,-7.277422256,-7.828086365,-6.72140024,-5.418231904 -1813,E119L,-0.013107576,-0.028284042,-0.773277697,-1.782227899,-2.748624492,0.009621956,-0.003319464,-0.022895688,0.069983826,-0.018177868,-0.038390216,-0.582917849,-0.963637544,-1.752131628,-1.81232417,-2.625766636,-2.871482347,1.8875736,0.891601369,-8.111070361,-6.127335304,-6.84986721,-8.990299294,-8.466697754,-10.12115224,-7.246228786,-5.58848306 -1814,E119N,-0.120584419,-0.039268838,-0.073064934,-0.00890441,-0.608434947,0.102338391,0.038506997,-0.279675834,-0.024991687,-0.009026778,-0.069510897,0.012504634,-0.158634502,-0.002215165,-0.015593654,-0.363966812,-0.852903082,0.770655303,1.521598533,-5.480216544,-4.872452866,-5.234579094,-5.839473305,-5.04298188,-6.411595573,-6.222045655,-2.562557682 -1815,E119Q,0.067221893,-0.016648171,-0.021277994,-0.024171668,-0.055457407,0.033561602,0.072002661,0.062441124,0.008176676,0.011670804,-0.044967146,0.048767262,-0.09132325,-0.026441495,-0.021901841,-0.049598853,-0.061315961,1.198641987,2.368205152,-1.638491614,-1.098014519,-1.812986115,-1.586809692,-1.64097541,-2.053672333,-3.748466943,-1.439937795 -1816,E119P,-0.046665984,-1.056239349,-1.78039466,-2.052073253,-2.895133679,0.058644553,0.065300174,-0.158632141,0.233915103,-1.052977591,-1.059501106,-1.941120384,-1.619668936,-2.081458035,-2.022688471,-3.085426811,-2.704840546,2.994787336,0.929476379,-8.891905582,-7.694458282,-8.528895508,-9.58120414,-9.023863731,-9.631106247,-9.71395341,-9.407631909 -1817,E119S,-0.011048661,-0.015268338,0.013415975,0.032591402,-0.364669541,0.080931762,0.072550667,-0.094647989,0.117821774,0.020995642,-0.051532317,0.055726628,-0.028894678,0.014100915,0.051081888,-0.270566868,-0.458772213,1.340198313,1.951727311,-4.23065016,-3.454488388,-4.408773605,-5.382678696,-2.746436874,-5.160873238,-5.393249125,-3.127076967 -1818,E119R,0.107251868,-0.026716763,-0.040606919,-0.30301448,-1.734968547,0.084484672,0.041286253,0.173217482,0.040687089,0.000950152,-0.054383677,0.033731003,-0.114944841,-0.118437624,-0.487591336,-1.96699974,-1.502937354,1.109945065,1.320443283,-4.307724948,-3.488356247,-4.966280853,-2.899113945,-5.384098732,-4.800774963,-5.814927519,-3.003518804 -1819,E119T,-0.043812728,-0.050105737,-0.034074847,-0.439345945,-1.904197339,-0.00197845,0.025871339,-0.113496795,0.10984029,0.002475552,-0.102687025,0.017552782,-0.085702475,-0.190991636,-0.687700254,-1.9179554,-1.890439278,1.164230687,1.326061778,-4.774644252,-3.326310326,-4.511568993,-6.240483215,-4.002391434,-5.792467293,-6.252612284,-2.49204337 -1820,E119W,0.114758286,-0.055911818,-1.11421463,-1.879983878,-2.695865472,0.031206706,0.193203568,0.036313003,0.052595816,0.099543384,-0.211367019,-1.012098821,-1.216330439,-1.916799439,-1.843168316,-2.966525705,-2.425205238,2.187481187,0.924705605,-9.301594263,-8.048908127,-8.285021011,-9.650076889,-10.65793174,-9.866033546,-7.093385975,-4.00566663 -1821,E119V,0.054693493,-0.147576713,-1.457448411,-1.58575783,-2.23644673,0.041332488,0.038918066,0.07046892,0.03300026,-0.07929504,-0.215858386,-1.529722161,-1.385174661,-1.910268572,-1.261247088,-2.922206277,-1.550687183,2.673647093,1.094959223,-6.592684633,-4.885019386,-6.064036591,-7.462946396,-6.603810814,-7.947609978,-6.951979112,-4.502924053 -1822,E119Y,0.007885101,-0.011861744,-0.574234846,-1.403272533,-2.12499127,0.061426217,0.107448004,-0.091677802,0.183644397,0.035115863,-0.058839351,-0.37787158,-0.770598112,-1.402478497,-1.404066568,-2.394212817,-1.855769722,2.199158356,1.263602691,-8.516695238,-7.010555946,-7.148606316,-9.521410561,-8.796994949,-10.10590842,-6.916279054,-3.767088222 -1823,L120A,0.02299752,-0.013729086,0.010712556,-0.06949089,-1.656683027,0.028566244,-0.048126712,0.094121751,-0.28792695,0.000316126,-0.027774298,-0.034713744,0.056138855,-0.063100748,-0.075881031,-1.722725199,-1.590640854,0.756881033,1.312874352,-6.779326323,-10.21371678,-5.063780914,-5.985266388,-5.482024605,-7.151842926,-5.504698507,-2.640429182 -1824,L120C,-0.101415136,-0.035107395,0.015466852,-0.218310167,-1.956852199,0.068187271,-0.109162506,-0.093667766,-0.157928415,-0.024750926,-0.045463863,-0.029902821,0.060836525,-0.096890654,-0.339729679,-1.827158862,-2.086545535,0.838262957,1.310877918,-9.26758956,-11.8202033,-7.914952667,-10.4553448,-8.57997422,-7.567472816,-8.546422005,-5.314053546 -1825,L120E,0.064091611,-0.827785131,-1.827650557,-2.334775426,-2.689091686,0.003009156,-0.03647872,0.164661942,0.113943352,-0.79526412,-0.860306142,-1.513840221,-2.141460893,-2.435134096,-2.234416756,-2.669124015,-2.709059356,2.276898686,0.5246398,-12.82088511,-15.08617767,-10.8400903,-13.7703979,-11.97115508,-12.43660458,-11.01015823,-10.46629924 -1826,L120D,0.074830658,-1.28167561,-1.706435665,-2.042349194,-2.635226081,0.021659634,0.0373184,0.112342916,-0.099936468,-1.115962242,-1.447388978,-1.985357598,-1.427513732,-2.342380042,-1.742318345,-2.576369962,-2.6940822,2.140236116,0.05332438,-12.27562912,-14.31069049,-10.3235269,-13.42916042,-10.806689,-12.50807878,-10.13489741,-7.910881902 -1827,L120G,0.032231806,-0.057572306,-0.911409424,-1.730082187,-2.804557751,0.038178103,-0.005341756,0.069805368,-0.052163686,-0.043639088,-0.071505523,-0.86985331,-0.952965538,-1.70103253,-1.759131844,-2.421098547,-3.188016954,2.705890477,1.431829424,-12.25745872,-14.95840295,-9.967017372,-13.12923133,-10.53961652,-12.69302542,-9.730856201,-7.238557733 -1828,L120F,-0.143083964,-0.070924935,-0.036593797,-1.320975046,-1.885399507,0.014019566,-0.072724628,-0.213443299,-0.176324814,-0.085733927,-0.056115942,-0.061889319,-0.011298275,-1.351385529,-1.290564562,-2.138217417,-1.632581597,2.532095335,1.616667816,-7.474878329,-8.921046371,-5.998237221,-8.518871803,-7.169236961,-6.76699929,-7.813022943,-5.475027282 -1829,L120I,-0.093062184,-0.033820483,-0.033177166,0.006083796,-1.593683033,0.030188814,-0.018884115,-0.167240253,0.025002269,-0.018894333,-0.048746633,-0.016407917,-0.049946414,-0.010497431,0.022665022,-1.856210659,-1.331155407,0.906164699,1.31388891,-4.420372446,-2.762978355,-4.785669693,-5.967418137,-3.733488632,-4.852307411,-5.797769323,-2.278558895 -1830,L120H,-0.022094599,-0.061687775,-0.096858537,-1.522162467,-2.436765693,0.053375293,-0.06435376,0.020164563,-0.166883257,-0.030332187,-0.093043362,-0.098367396,-0.095349677,-1.575365158,-1.468959776,-2.549717767,-2.323813618,2.492908042,1.454956032,-9.823517642,-12.09361266,-7.385449371,-12.39152749,-9.390818474,-7.856180222,-8.445615888,-5.994888233 -1831,L120K,-0.071753928,-1.041858582,-2.090939601,-2.378398123,-2.732714383,-0.01130161,-0.041366793,-0.102141062,-0.577057722,-0.984354745,-1.099362419,-2.28947867,-1.892400531,-2.470409856,-2.286386389,-2.704399776,-2.76102899,2.003800039,-0.19557209,-12.30462457,-14.22532285,-10.445853,-13.90957055,-11.00230421,-11.94007227,-11.01015823,-10.46629924 -1832,L120M,-0.035090458,-0.087431042,0.020338493,-0.014890736,-0.31533879,0.035218895,-0.009748616,-0.060432299,-0.123417563,-0.031796822,-0.143065262,-0.0047638,0.045440786,-0.08853473,0.058753259,-0.30009818,-0.330579399,1.645720261,2.145514509,-4.683491951,-6.013356056,-4.850749702,-5.353772354,-3.651919601,-3.547662041,-7.099233078,-3.770962523 -1833,L120N,-0.166891696,-0.074843088,-1.083139164,-1.921642949,-2.926474207,0.008922233,-0.07400726,-0.259776132,0.268040318,-0.092699934,-0.056986242,-1.117983163,-1.048295164,-2.039277038,-1.804008859,-2.875326949,-2.977621464,2.240315851,0.881768638,-12.29841585,-14.57026831,-10.18499422,-14.13408275,-11.48103595,-11.12169802,-11.01015823,-10.46629924 -1834,L120Q,-0.104077028,-0.07492291,-0.694368538,-1.668685239,-2.673516497,0.036116578,-0.118269995,-0.089884061,-0.232562033,-0.062568608,-0.087277211,-0.61136972,-0.777367355,-1.574952657,-1.76241782,-2.712032564,-2.635000429,2.004604547,1.009126636,-11.75469424,-14.05481695,-10.04402764,-13.54320495,-10.36904958,-10.76237208,-11.01015823,-10.46629924 -1835,L120P,-0.20267906,-1.448452995,-1.73058359,-2.141294259,-2.779291773,0.026533965,-0.083219994,-0.322138125,-0.000419811,-1.572438516,-1.324467473,-1.899612582,-1.561554597,-2.089687147,-2.192901371,-2.67355563,-2.885027916,-0.17015593,-0.979746211,-12.81945266,-14.8898895,-11.15148304,-13.60405658,-11.79561839,-12.65621578,-11.01015823,-10.46629924 -1836,L120S,-0.129646444,-0.006451923,-0.14635512,-1.459169986,-2.488623444,0.041843558,0.00296084,-0.262253727,-0.110318503,0.013191378,-0.026095224,-0.085112788,-0.207597452,-1.344003575,-1.574336396,-2.205164207,-2.77208268,2.281240774,1.430109218,-10.49130075,-12.89355479,-8.259694817,-11.0396804,-9.542776299,-10.72079745,-8.628326632,-6.871502998 -1837,L120R,0.025515432,-1.564780399,-1.724785792,-2.046684959,-2.676454953,0.024367838,-0.014921218,0.065952082,-0.109276494,-1.815593525,-1.313967272,-1.740506208,-1.709065375,-2.018347407,-2.07502251,-2.854397318,-2.498512588,-0.034350843,-1.08917561,-12.20881358,-14.399302,-10.15873238,-14.62317763,-11.14048022,-10.72237565,-11.00429669,-10.44368496 -1838,L120T,-0.148518615,-0.054859969,-0.050781527,-1.236380863,-2.41338899,0.045855872,-0.024277875,-0.272759355,0.068467963,-0.057697217,-0.05202272,-0.045169591,-0.056393462,-1.063963954,-1.408797771,-2.234822287,-2.591955693,2.10986661,1.396935549,-9.810568321,-11.57798013,-8.117021362,-10.34708717,-9.033279045,-9.977473892,-8.627261715,-3.609139158 -1839,L120W,-0.073859018,-1.120271313,-1.674850023,-1.9394298,-2.643231062,-0.081661496,-0.043160305,-0.10455773,-0.099936468,-1.255297746,-0.985244879,-1.861451667,-1.488248379,-2.042382852,-1.836476747,-3.179462759,-2.106999365,3.274460714,1.06544634,-10.93678209,-12.20441442,-9.316925919,-13.09140387,-10.46100502,-9.610161217,-9.598967032,-7.238559795 -1840,L120V,0.022592211,-0.034971125,-0.033748045,-0.749995458,-1.783373826,0.019700017,-0.02112445,0.066308871,-0.022639365,-0.03478392,-0.035158329,-0.067708891,0.000212801,-0.437509459,-1.062481456,-1.776018249,-1.790729402,1.68802588,1.438267036,-6.121450858,-5.411335167,-5.318412331,-7.063089249,-5.965684044,-6.848733498,-6.275142444,-2.403078808 -1841,L120Y,-0.19271619,-0.067237223,-0.976410861,-2.069672038,-2.901109553,-0.035069896,-0.138149458,-0.247282921,0.094638197,-0.081807966,-0.052666479,-0.987292098,-0.965529624,-2.196252007,-1.943092069,-2.907363181,-2.894855924,1.942705547,0.685554087,-9.252887593,-10.44423698,-7.110301193,-12.03281886,-8.863742226,-7.813338707,-8.984130329,-5.543246839 -1842,C121A,0.089049316,-0.051104409,-0.016551268,-0.03542283,-1.367100962,0.113933064,-0.060064549,0.238163181,-0.05996154,-0.029643719,-0.072565098,-0.059738022,0.026635486,-0.000203464,-0.070642195,-1.111149637,-1.623052287,0.769943566,1.354085498,-9.043801167,-7.44146653,-8.434157898,-12.06368692,-7.945701004,-9.333993485,-6.076570661,-0.423668018 -1843,C121E,-0.387301187,-0.557497242,-1.674703959,-2.123269597,-3.29997929,0.138492817,-0.099225645,-0.675376729,-0.046996563,-0.434256192,-0.680738291,-1.66993764,-1.679470277,-2.068476263,-2.178062931,-3.046647825,-3.553310754,2.781318508,1.010989652,-14.72908192,-13.00862576,-13.79711082,-18.29942474,-14.82673293,-13.71351537,-10.09918734,-7.014622481 -1844,C121D,0.214792049,-1.165109903,-1.696132149,-1.940013053,-2.63960149,0.199178537,0.013463566,0.416120531,-0.198264238,-1.331960468,-0.998259338,-1.708537425,-1.683726872,-1.764653367,-2.115372738,-2.742824929,-2.53637805,3.932203176,1.751915249,-15.4182007,-13.17122884,-15.8404536,-18.83912002,-14.96226876,-14.27793228,-11.08138346,-9.465434804 -1845,C121G,-0.241937707,0.013519752,-0.019227142,-0.77877055,-1.794543071,0.150088741,-0.05195228,-0.431923133,-0.102299371,-0.001209022,0.028248525,-0.071658556,0.033204272,-0.339010089,-1.218531011,-1.884931691,-1.704154451,1.505712542,1.375899656,-11.54551561,-10.14187,-11.1756465,-14.22047592,-11.23001231,-10.95957333,-7.370933,-4.026302292 -1846,C121F,-0.074983199,-0.58500169,-1.54289959,-2.627401113,-2.977504548,0.110213422,0.026360594,-0.176326991,-0.007488021,-0.454548041,-0.715455338,-1.677697724,-1.408101456,-2.636903653,-2.617898572,-2.916105211,-3.038903885,1.454341218,0.077050227,-11.13681386,-11.91545425,-10.32494781,-11.68280393,-11.3648324,-10.39603092,-8.191645538,-4.53904156 -1847,C121I,0.259461097,0.00710009,0.032175185,-0.656352659,-1.655882633,0.033758198,0.032520903,0.48640129,-0.323202975,0.045457874,-0.031257694,0.005090409,0.059259961,-0.292501931,-1.020203386,-1.870556566,-1.441208699,1.383009406,1.356589223,-11.24472802,-10.51708639,-10.29750864,-15.45507884,-10.97010925,-8.983856979,-6.147742755,-1.132604431 -1848,C121H,0.245762969,-1.008258141,-1.989788875,-2.160605761,-2.933258216,0.157037449,0.054128558,0.437397379,-0.077379192,-1.204210754,-0.812305527,-1.838352013,-2.141225737,-2.049369915,-2.271841607,-3.173669513,-2.692846919,3.104662032,0.953945461,-13.60248731,-12.85469775,-13.90513334,-14.56083838,-14.83281078,-11.8589563,-11.08138346,-9.465434804 -1849,C121K,-0.34705847,-1.763990187,-2.032630988,-2.058647607,-3.147311669,0.103402808,0.001442819,-0.695559759,0.055665779,-2.018135274,-1.5098451,-2.248584195,-1.81667778,-2.304700137,-1.812595076,-2.884931691,-3.409691647,-0.766722023,-1.109007334,-14.91392062,-13.02578659,-14.68414422,-17.83433099,-15.31583733,-13.70950399,-11.08138346,-9.465434804 -1850,C121M,-0.357090377,-0.014821632,-0.021657572,-0.031270103,-1.306918993,0.047801085,-0.015693186,-0.698487567,-0.113943352,-0.047996466,0.018353202,-0.09943939,0.056124247,-0.037940453,-0.024599752,-0.910428078,-1.703409907,1.073085014,1.443914842,-11.3720801,-10.82752172,-10.36049347,-15.44360423,-10.9847624,-9.244018669,-6.984676546,-2.000592453 -1851,C121L,-0.274144408,-0.00364386,-0.028326804,-0.153440919,-1.621818619,0.05121568,-0.030056168,-0.518232647,-0.028636554,-0.060252387,0.052964667,-0.131614388,0.074960781,-0.054391052,-0.252490786,-1.838188287,-1.40544895,0.961539069,1.31623328,-9.27140817,-8.954845261,-9.071960663,-13.2588564,-9.148336563,-5.923041962,-5.586063383,-0.280640812 -1852,C121N,0.067136036,-0.172269063,-1.523141251,-2.145503129,-2.918155585,0.158242551,0.023355084,0.110916988,-0.101354225,-0.072471825,-0.2720663,-1.518205727,-1.528076774,-1.933343611,-2.357662647,-3.057643209,-2.77866796,0.886146904,0.052084602,-11.77903896,-9.782613403,-11.61645774,-14.00282105,-11.88408625,-11.60921635,-8.49840483,-4.784146802 -1853,C121Q,-0.281436902,-0.010642893,-1.033263262,-1.976229951,-2.763864018,0.146684539,0.011581034,-0.574454837,-0.05154419,-0.113600046,0.092314261,-0.946108959,-1.120417565,-2.051442923,-1.901016978,-2.029614486,-3.49811355,3.893253459,2.469946035,-13.86988745,-11.68733726,-14.08540994,-17.3102149,-13.91311222,-12.35336292,-9.145917698,-5.44339499 -1854,C121P,0.014326252,-1.170731654,-1.435815141,-1.895162396,-3.318329849,0.148917406,0.004487111,0.024165393,0.007760084,-1.558972692,-0.782490615,-1.92564136,-0.945988921,-1.959480907,-1.830843884,-2.93765247,-3.699007228,-0.425027163,-1.007267713,-15.58216019,-13.98711913,-15.27742196,-18.6552596,-15.16515134,-14.82584893,-11.04661982,-9.256621153 -1855,C121S,-0.004262668,-0.032590156,-0.061782751,-1.129522757,-2.140735839,0.13235694,-0.020355916,0.011830581,-0.021919967,-0.045099001,-0.02008131,-0.128704409,0.005138907,-0.887250888,-1.371794625,-2.196415669,-2.085056009,2.048854253,1.408475585,-8.284762036,-7.853041916,-7.194481049,-10.08126069,-7.365001717,-8.930024811,-5.40203406,-2.414247223 -1856,C121R,-0.122144979,-1.386365304,-1.743061725,-1.556369895,-2.98414135,0.184954501,0.006456412,-0.25074637,-0.099932638,-1.588786801,-1.183943807,-1.911989776,-1.574133674,-1.875351664,-1.237388126,-2.967466579,-3.00081612,-0.178676887,-1.084714557,-15.01716115,-12.8946364,-15.36389944,-18.2371652,-15.1258298,-13.46427489,-11.07550393,-9.444781489 -1857,C121T,0.087605024,-0.010107627,-0.629777312,-1.894506356,-2.611475847,0.13991848,-0.007830072,0.183040119,-0.0027929,-0.01619398,-0.004021274,-0.510628628,-0.748925996,-1.654198342,-2.13481437,-2.570221998,-2.652729696,1.808952273,0.896942594,-10.81346519,-9.291862457,-10.28919936,-13.52349158,-10.45933512,-10.50343742,-7.443044345,-3.642841996 -1858,C121W,-0.313893707,-1.342967234,-1.840516085,-1.936758155,-2.747270968,0.139367785,-0.05045695,-0.577330463,-0.100440882,-1.635086821,-1.050847647,-2.342656997,-1.338375173,-2.00083293,-1.87268338,-2.501883238,-2.992658697,-0.052308379,-1.052172302,-14.70164459,-13.9648306,-14.65707964,-16.89547982,-14.73827728,-13.25255561,-11.08138346,-9.465434804 -1859,C121V,-0.158676462,0.024574349,0.011321338,-1.439136199,-2.614484462,0.100730917,0.039221286,-0.35657421,-0.032273306,-0.026572017,0.075720714,-0.05240148,0.075044156,-1.343671638,-1.53460076,-2.452176969,-2.776791955,0.784408654,0.724504208,-12.54662394,-10.8514162,-12.78869063,-16.4584889,-12.49167668,-10.14284729,-6.27722098,-1.625096725 -1860,C121Y,0.047350641,-1.318099174,-2.075009417,-2.201848718,-2.941027778,0.149221966,0.077393558,0.017307723,-0.210853365,-1.52309098,-1.113107367,-1.846293955,-2.303724879,-1.969356687,-2.434340748,-3.026709495,-2.855346061,3.549455075,1.144476971,-11.52922771,-12.26616351,-11.2321983,-11.5797365,-11.9909801,-10.57706013,-9.358709401,-5.253733566 -1861,S122A,0.241789028,0.014265926,0.014197302,0.017726278,-0.020963348,-0.021860242,-0.077277143,0.560855199,,0.049056704,-0.020524853,-0.001492272,0.029886876,-0.002413747,0.037866303,-0.022953799,-0.018972897,1.295753468,2.63461228,-0.468063541,-0.909422997,-0.358737823,0.332229744,-1.009562325,-0.394824303,-2.312838131,1.138399176 -1862,S122C,0.295501434,-0.016514933,-0.025305624,-0.020250367,-0.640035726,0.04877594,0.162551637,0.428451231,,-0.022536423,-0.010493443,-0.029259877,-0.021351371,-0.000521753,-0.03997898,-0.514632166,-0.765439285,0.867855422,1.491384943,-5.971429758,-5.576058472,-7.012711632,-6.079024307,-6.869572586,-4.319781792,-6.71498637,-2.967315985 -1863,S122E,-0.17085546,0.006414537,-0.021761888,0.026649234,0.036991756,-0.014261548,0.067474093,-0.409185013,,0.000935148,0.011893925,-0.062625726,0.01910195,0.035329037,0.017969431,-0.006971861,0.080955373,1.129761546,2.579313822,-0.200315538,-0.657888184,-0.125178635,1.148686676,-0.790706474,-0.576491074,-1.695662839,1.761568381 -1864,S122D,-0.275600541,0.01840403,0.019735145,0.083809573,0.050177167,0.032125816,-0.018137934,-0.533063148,,0.032539446,0.004268613,-0.002333891,0.04180418,0.078320838,0.089298308,0.060110454,0.040243879,1.094874774,2.793097824,-0.546352617,-1.183285957,0.100588707,-0.077918282,-1.226565208,-0.344582344,-2.5526485,1.019432537 -1865,S122G,0.267659731,-0.001720029,0.001057512,0.009623286,0.025668662,-0.003772439,0.061338394,0.473981068,,0.039880992,-0.043321049,0.009261048,-0.007146025,0.036787454,-0.017540883,0.019111992,0.032225332,1.129499537,2.631264114,-4.272196315,-4.309300751,-4.406683655,-3.919165031,-3.353578148,-5.37225399,-4.268429153,-0.966533791 -1866,S122F,0.223634311,-0.058547854,-0.057664327,-0.086062461,-0.159042943,-0.029089707,-0.063093786,0.510362407,,0.047415731,-0.164511439,0.049316847,-0.164645501,0.030378638,-0.202503559,-0.043411736,-0.274674149,1.197729864,2.450691772,-5.070621295,-5.519624107,-5.394254601,-4.364059868,-4.901599686,-5.173568214,-4.559770289,-1.210799875 -1867,S122I,0.383333093,-0.034974694,0.015222869,-0.136142781,-0.154171419,-0.031686699,0.067576124,0.699090061,,0.040318451,-0.110267839,-0.008129338,0.038575076,-0.042909856,-0.229375705,-0.129169277,-0.179173561,1.323753168,2.196593886,-6.495264589,-6.186572525,-7.465992767,-6.7271576,-6.349600517,-5.746999535,-4.964815043,-1.634148279 -1868,S122H,-0.034118307,0.045482843,0.017067295,-0.012360421,0.011127575,0.019762977,0.049651801,-0.117888415,,-0.022894287,0.113859973,-0.041038363,0.075172952,-0.011838168,-0.012882673,-0.023634075,0.045889224,1.327193941,2.559648193,-1.463134222,-1.788205711,-1.114383751,-1.216043495,-1.269265854,-1.927772301,-2.99903092,-0.200730538 -1869,S122K,0.458420799,-0.134713405,-0.088577747,-0.036015889,-0.070357872,0.007972893,0.112725785,0.804115813,,-0.015252394,-0.254174415,-0.018578482,-0.158577011,-0.007466321,-0.064565457,-0.044879388,-0.095836355,1.359140214,2.486134582,-2.184460385,-3.358229805,-2.60639222,-1.932221634,-1.63794754,-1.387510727,-3.086993337,0.368000111 -1870,S122M,0.211697407,-0.315487525,-0.11627018,-0.196368429,-0.229901572,-0.002997116,-0.480901039,0.904295852,,-0.059380222,-0.571594827,-0.030298846,-0.202241513,0.012730108,-0.405466965,-0.109337206,-0.350465937,1.33716199,2.267876502,-6.276913095,-6.25337159,-5.806894333,-8.444610039,-5.62410144,-5.255588074,-4.878974259,-0.615874059 -1871,S122L,0.331875076,-0.000562799,0.004137846,-0.026732443,-0.00930864,-0.043199318,0.072995392,0.59075476,,0.000778531,-0.001904128,0.007673787,0.000601905,0.027049215,-0.0805141,-0.030728976,0.012111697,1.243379167,2.524836693,-4.752742255,-4.374715561,-3.819661934,-7.101070763,-5.34078421,-3.127478806,-4.162259458,-0.524134013 -1872,S122N,0.320454327,-0.003168969,0.023173239,0.043213386,0.028354137,-0.010935186,0.016423602,0.624485052,,-0.012890945,0.006553007,0.042533507,0.00381297,0.019973674,0.066453097,0.021332323,0.03537595,1.227535504,2.729066012,-2.117115833,-2.690763145,-2.226560883,-2.459575127,-1.918878304,-1.289801704,-3.620829591,-0.718997155 -1873,S122Q,0.249523311,-0.015866081,-0.009192786,-0.053999738,0.031705228,-0.043940702,0.068019508,0.431027113,,-0.017252361,-0.014479801,0.00291218,-0.021297751,0.006308247,-0.114307723,-0.006377546,0.069788001,1.266443155,2.720386773,-2.060977135,-1.970427147,-1.312899223,-2.330922699,-2.471541809,-2.219094795,-3.192079504,0.193925428 -1874,S122P,0.11809733,0.012619677,-0.239451331,-0.88923865,-1.137558841,0.035295834,0.040650184,0.195544475,,0.00224526,0.022994093,-0.41800113,-0.060901531,-1.611457371,-0.167019928,-2.223441825,-0.051675856,2.53270911,1.479755169,-8.071793167,-8.280587357,-7.844758499,-8.26466362,-8.242219887,-7.726736473,-8.595015477,-6.994142089 -1875,S122R,-0.003072379,0.020958215,0.015684232,0.020640951,0.004943197,-0.008013905,0.057109801,-0.063254559,,-0.022662572,0.064579001,-0.002731389,0.034099852,0.012808469,0.028473432,-0.052773394,0.062659787,1.378716015,2.53968567,-2.023537766,-1.914387321,-0.687749039,-3.463144691,-1.46534671,-2.587061066,-3.939447523,1.010952053 -1876,S122T,0.172842962,0.012916524,0.0137892,0.024728274,-0.048347505,-0.02444848,0.005936381,0.339749542,,0.025366199,0.000466848,0.014904175,0.012674225,0.058558463,-0.009101915,-0.029832525,-0.066862485,1.267893708,2.504631358,-2.969045012,-2.438888817,-3.637488983,-3.462279503,-3.247414368,-2.059153389,-3.508781498,1.098096579 -1877,S122W,0.367604559,-0.048617348,-0.030193548,-0.080856729,-0.065610253,-0.028691743,0.146208672,0.589000446,,0.002701772,-0.099936468,-0.025093462,-0.035293633,-0.002375619,-0.159337839,-0.099680336,-0.03154017,1.395513414,2.366341084,-7.237980917,-7.111803734,-7.737459572,-6.803167793,-6.776353699,-7.761119789,-5.75446124,-2.128534863 -1878,S122V,0.426733834,-0.038884959,0.065571219,-0.011582772,-0.010096556,-0.031445699,0.137305588,0.716162079,,-0.025087649,-0.052682269,-0.005936972,0.137079409,-0.023463925,0.000298382,-0.049051713,0.028858601,1.136327568,2.266783327,-4.515405168,-4.410671288,-6.006736038,-4.609441376,-4.834155624,-2.716021515,-3.795583962,-0.28350528 -1879,S122Y,0.036594234,-0.028142597,-0.026150289,-0.007976202,-0.017809199,0.006122435,0.03705647,0.036131997,,-0.034832558,-0.021452635,-0.022567438,-0.029733139,0.025267531,-0.041219935,-0.034344716,-0.001273681,1.340955651,2.612253322,-5.121678334,-4.970863602,-6.477635902,-4.128093704,-3.699550697,-6.332247765,-5.689018936,0.361436183 -1880,A123C,-0.280185439,-0.004247023,-0.046905698,-0.034296357,-1.28428257,0.083669736,-0.156805433,-0.403565445,0.311229434,-0.031892516,0.023398471,-0.007175963,-0.086635432,-0.023339686,-0.045253027,-0.977935776,-1.590629364,0.965235852,1.404744514,-11.67593257,-10.08993374,-10.55083051,-12.70024502,-12.45265037,-12.5860032,-9.739678394,-6.625083583 -1881,A123E,-0.239819188,-0.015990868,-0.009362643,-1.441669809,-2.480116703,-0.025782717,-0.077738011,-0.401900365,0.179127022,-0.005856268,-0.026125467,-0.036236915,0.017511629,-1.056483341,-1.826856277,-2.494428955,-2.465804451,0.79988404,0.755326033,-9.767012602,-7.23729052,-8.53442942,-11.43130537,-10.25346146,-11.37857624,-7.351486929,-3.175513342 -1882,A123D,-0.247686796,0.016535884,-0.658586558,-1.514936134,-2.27741418,0.065728023,-0.038841212,-0.456532379,0.293094974,-0.014330209,0.047401977,-0.525803966,-0.791369149,-1.439023245,-1.590849023,-2.358454919,-2.196373441,2.417369461,1.392352095,-9.140484811,-6.305842079,-8.676863861,-10.2670778,-9.581106514,-10.87153381,-7.562071424,-4.027847688 -1883,A123G,-0.260528661,-0.003458532,-0.027570498,0.011865837,-1.557945569,0.040060509,-0.10542452,-0.415632802,0.215831415,-0.028306654,0.021389591,-0.011264472,-0.043876523,-0.008235165,0.031966839,-1.532332805,-1.583558332,0.854143894,1.330249369,-6.102301631,-3.943840469,-4.943286308,-8.149883514,-7.292417595,-6.182080269,-6.156265729,-3.863174216 -1884,A123F,-0.333245641,0.011224287,-0.250954361,-1.39422107,-2.64344777,0.057670803,-0.224140546,-0.442350736,0.247718915,-0.027337084,0.049785658,-0.193325588,-0.308583134,-1.562476823,-1.225965316,-2.628036532,-2.658859008,1.185753524,0.746814024,-12.18665587,-11.66231805,-8.992744476,-14.28416422,-13.75072243,-12.24333016,-8.138436035,-2.99935023 -1885,A123I,-0.28281536,0.066103649,0.013376095,-0.977584401,-1.679705983,0.010823077,-0.124134829,-0.441495891,0.174789026,0.088949467,0.04325783,0.016985613,0.009766577,-0.774172424,-1.180996377,-1.756394928,-1.603017038,2.18436879,1.645787542,-7.746696703,-7.575559509,-4.827628517,-7.810091949,-8.528251946,-9.991951591,-6.303298453,-4.066275166 -1886,A123H,-0.222591453,0.006072657,-0.065716493,-1.46797117,-2.266565409,-0.015309103,-0.081360048,-0.363822857,0.24085743,-0.025540623,0.037685937,-0.071483495,-0.05994949,-1.284121285,-1.651821054,-2.24931045,-2.283820368,0.833057151,0.736014051,-11.34389446,-10.28763858,-9.163620857,-11.60489192,-10.06223399,-15.60108694,-8.242547434,-3.804352764 -1887,A123K,-0.318796332,-0.002167327,-1.222976178,-1.999564676,-2.514617711,-0.063986326,-0.191014763,-0.446577901,0.187990482,-0.026377935,0.022043281,-1.008153248,-1.437799107,-1.817367698,-2.181761653,-2.162768104,-2.866467318,3.697827593,2.325580277,-12.30403358,-10.04480191,-9.186185318,-13.98518378,-12.29653608,-16.00746079,-7.979542192,-2.691837344 -1888,A123M,-0.389051091,-0.027207689,-0.093753905,-1.553111933,-2.704317891,0.046070637,-0.254399159,-0.523703022,0.24057396,-0.014181656,-0.040233721,0.030792535,-0.218300344,-1.390198072,-1.716025794,-2.724603093,-2.684032688,0.676974188,0.711887917,-8.64358615,-8.824457672,-6.349230156,-10.44138876,-10.34778276,-7.255071396,-6.783530174,-3.085595402 -1889,A123L,-0.326070116,-0.000561003,-0.187264404,-1.320231538,-2.310294405,0.05893954,-0.18402865,-0.468111581,0.274890704,0.00421037,-0.005332375,-0.086077645,-0.288451163,-1.383759859,-1.256703216,-2.553069006,-2.067519803,0.766047135,0.718781139,-9.574247034,-9.554737724,-6.507860336,-10.60663165,-11.62561115,-9.576394318,-6.657953858,-0.500251245 -1890,A123N,-0.37273222,-0.106869372,-0.011476841,-1.109896215,-2.701399048,0.064470691,-0.212902925,-0.532561514,0.332367328,-0.133139253,-0.080599491,-0.042472061,0.01951838,-0.566219738,-1.653572691,-2.082248507,-3.320549589,1.712258903,1.369956864,-11.14018086,-8.998755005,-10.1639077,-12.48321461,-10.9274249,-13.1276021,-7.707709579,-4.479306169 -1891,A123Q,-0.382757312,-0.091981034,-0.13192312,-1.36173126,-2.533981274,0.081510005,-0.232236816,-0.533277807,0.161118336,-0.128846739,-0.055115329,-0.079335839,-0.184510401,-1.264091652,-1.459370868,-2.224916011,-2.843046537,0.99923322,0.756627726,-11.37526737,-9.989266571,-8.981983078,-13.51394772,-10.72880686,-13.66233263,-7.325977146,-2.618636681 -1892,A123P,-0.295442966,-1.303264907,-1.369459938,-1.528745809,-2.277657644,0.061768009,-0.127254148,-0.463631783,0.109867201,-1.72525497,-0.881274843,-1.762648598,-0.976271277,-1.965750513,-1.091741104,-2.987844528,-1.56747076,-0.527321094,-1.028536408,-11.02525557,-10.07382784,-10.06141911,-11.84924564,-12.17361216,-10.96817309,-8.350854372,-4.889756063 -1893,A123S,-0.257709204,0.009110295,-0.014811205,0.011556071,-0.275678578,0.021270194,-0.136060412,-0.379357996,0.181668763,-0.016424983,0.034645573,-0.008990326,-0.020632084,-0.006522962,0.029635104,-0.200398268,-0.350958888,1.311260259,2.041412754,-7.36018342,-6.383967773,-6.493595573,-8.412306267,-7.565504158,-7.945543327,-7.091799427,-3.131037409 -1894,A123R,-0.260929563,-0.255169872,-1.432048823,-2.130741892,-2.959989393,0.031329449,-0.112370978,-0.409488147,0.2646768,-0.196879039,-0.313460705,-1.416348787,-1.447748859,-2.038823243,-2.222660541,-2.711582583,-3.208396202,2.61870926,1.060856871,-10.8422903,-8.252465263,-8.575836967,-13.44795206,-9.441289474,-14.49390773,-6.374985589,-2.200517873 -1895,A123T,-0.125126247,0.00345706,0.008159428,-0.17994204,-1.578150206,0.043713545,-0.09373254,-0.156519953,0.156582018,-0.015201832,0.022115952,0.011412207,0.004906649,-0.09117516,-0.268708919,-1.691848071,-1.46445234,0.876558307,1.323936171,-7.548103804,-6.019906517,-6.250928284,-9.485409157,-7.490484306,-8.493790756,-7.176424603,-4.785366407 -1896,A123W,-0.281376845,0.023298695,-0.613395525,-1.435870448,-2.604028737,0.005447228,-0.143175748,-0.419577942,0.260115913,-0.003160186,0.049757575,-0.499551266,-0.727239783,-1.588374107,-1.283366788,-2.452288453,-2.755769021,2.32256759,1.259818873,-13.22285313,-11.60270753,-10.2959799,-15.21126812,-14.18517313,-14.81913696,-8.100618754,-3.470832843 -1897,A123V,-0.220493947,-0.013733802,-0.046557558,-0.046080508,-1.466993592,0.08266781,-0.018667245,-0.422320648,0.182850843,-0.026038743,-0.00142886,-0.03501895,-0.058096165,-0.007036873,-0.085124142,-1.539900443,-1.394086741,0.655303947,1.316725554,-6.858876115,-7.315949051,-4.776024055,-6.953280403,-7.797590599,-7.451536469,-6.360495091,-3.574983415 -1898,A123Y,-0.280417522,-0.059911254,-0.030064585,-1.606492213,-2.245268831,-0.001969492,-0.156881915,-0.403953129,0.271199218,-0.13811466,0.018292153,0.005232019,-0.065361189,-1.467849572,-1.745134853,-2.563372504,-1.927165158,0.765282634,0.711271086,-11.74887883,-10.70017768,-8.65470108,-11.64724389,-12.05583648,-15.68643504,-7.999499028,-1.627886676 -1899,A124C,-0.011634577,-0.017851698,-0.010291103,0.034677989,-0.919172293,0.050435432,0.013957159,-0.037226313,0.029709084,0.026703898,-0.062407294,0.029588993,-0.050171198,0.110700666,-0.041344689,-0.615274866,-1.22306972,0.571892388,1.386581536,-10.24298311,-10.65081633,-12.1924863,-7.745605728,-9.61734063,-11.00866655,-7.908494062,-5.079621127 -1900,A124E,-0.038411509,-0.896375801,-2.073460304,-2.468136461,-2.721775029,0.064547819,-0.026702534,-0.050120483,0.068338486,-0.682755028,-1.109996573,-2.046636421,-2.100284187,-2.178244903,-2.758028018,-2.430280839,-3.013269218,0.821761268,-0.450770207,-11.8486739,-11.70452618,-13.75140367,-9.762016579,-11.06749381,-12.95792925,-10.31075578,-9.737882625 -1901,A124D,-0.090187779,-0.91483705,-1.719612099,-2.033362845,-2.468590365,0.07118087,-0.087670979,-0.092704578,0.076058108,-0.81857446,-1.011099639,-1.871206692,-1.568017505,-1.905905161,-2.160820529,-2.555881106,-2.381299623,3.721601301,1.745826015,-12.35735396,-12.42372642,-13.95276357,-10.48531007,-11.99137843,-12.93359134,-10.31777227,-9.781867988 -1902,A124G,-0.002706486,0.057796238,0.000145854,0.027665711,-1.301310383,0.05461385,0.007662751,-0.013075722,0.04140334,0.055089234,0.060503242,0.022150737,-0.021859029,0.054080289,0.001251133,-1.222873311,-1.379747455,0.636832294,1.332523842,-6.81752935,-7.647071999,-7.354613831,-4.697074593,-7.307185425,-7.081700905,-7.058506488,-4.496111818 -1903,A124F,-0.027110456,-1.391661003,-2.039531853,-2.371738641,-2.926407205,0.013374345,-0.028052171,-0.02616874,-0.094704317,-1.460740738,-1.322581267,-2.094243663,-1.984820042,-1.924822149,-2.818655132,-2.477888081,-3.374926328,0.347011226,-0.895631023,-16.15089619,-16.40157903,-18.29852361,-14.83403253,-14.50169779,-16.718648,-10.31777227,-9.781867969 -1904,A124I,0.020092405,0.046904718,0.0672466,-0.860383755,-1.774834631,0.090141551,0.04529354,-0.00510873,0.031281034,0.021859316,0.071950119,0.029480406,0.105012794,-0.422251014,-1.298516496,-2.32264696,-1.227022301,1.426507104,1.280433052,-9.165272189,-10.68651352,-11.30078786,-6.199285019,-7.949799057,-9.689975487,-6.179921999,-3.511875505 -1905,A124H,-0.03561949,-1.438066032,-2.0268643,-2.189097057,-3.064254649,0.102773805,-0.011478255,-0.059760725,-0.080665682,-1.615081399,-1.261050665,-1.78482703,-2.268901569,-1.819525499,-2.558668614,-3.071561435,-3.056947863,0.088695815,-1.004131641,-13.77943121,-13.67799036,-14.79833383,-10.7765264,-12.50733798,-17.1369675,-10.31777227,-9.781868017 -1906,A124K,0.012278438,-1.552713314,-2.030105193,-2.458254744,-3.012923308,0.060417198,0.049038529,-0.024481653,-0.08171551,-1.460401578,-1.64502505,-2.035912556,-2.024297829,-2.167521038,-2.74898845,-2.720586969,-3.305259646,0.276536292,-0.919275001,-13.23416453,-12.93221961,-14.73641473,-10.16145316,-12.1447118,-16.19602334,-10.31777227,-9.781867995 -1907,A124M,-0.063068996,-0.003268258,-0.014727211,0.027366344,-1.847959866,0.019126091,-0.047494325,-0.078643666,0.058836012,0.058684178,-0.065220693,0.055677948,-0.08513237,0.086701178,-0.03196849,-1.60519355,-2.090726181,0.414995159,1.304244792,-8.963420807,-10.36260567,-11.86793983,-5.932270409,-7.675324394,-8.97896373,-6.300651534,0.161701371 -1908,A124L,0.003243602,0.014383091,-0.169209653,-1.53856309,-2.491934679,0.011818531,0.01393761,-0.007450407,0.017757,-0.024067934,0.052834115,-0.174618395,-0.16380091,-1.259976709,-1.81714947,-2.327147462,-2.656721895,1.184126442,0.797379034,-12.75066125,-13.00720635,-15.15957541,-9.397731628,-11.29902584,-14.88976703,-7.693431397,-4.880356316 -1909,A124N,-0.039626014,-0.008471772,-0.028157773,-1.207287424,-2.741476684,0.015503517,-0.036035639,-0.043216388,-0.041601659,-0.029751527,0.012807984,-0.0714741,0.015158554,-0.834734446,-1.579840402,-2.200713734,-3.282239633,1.790684639,1.339065403,-10.6062467,-10.34700438,-12.3388198,-7.862363213,-10.39596574,-12.08708037,-8.010214371,-4.99488381 -1910,A124Q,-0.05570425,0.044020779,-0.877571678,-1.851658241,-2.832719239,0.086177941,-0.06602153,-0.04538697,-0.03298095,0.019766112,0.068275446,-0.565131479,-1.190011876,-1.671916377,-2.031400104,-2.577164827,-3.08827365,1.878655473,0.916639527,-12.82643978,-12.754561,-13.9773849,-10.14203616,-11.78095783,-15.477259,-10.12751286,-8.788685144 -1911,A124P,-0.040167367,-1.507453586,-1.889053133,-2.102559946,-2.842762441,0.040570557,-0.033665618,-0.046669116,-0.043785475,-1.580527939,-1.434379232,-1.799644004,-1.978462261,-1.827356352,-2.37776354,-2.353550137,-3.331974744,-0.037768281,-1.003528998,-11.74818231,-12.28343485,-12.97845091,-9.607790573,-11.17090613,-12.70032908,-10.31777227,-9.781868054 -1912,A124S,0.003944871,0.032996437,-0.01380044,-0.014520593,-0.166790065,0.022708655,-0.000736409,0.008626151,0.014726154,0.043625708,0.022367165,-0.030297945,0.002697065,0.009615455,-0.03865664,-0.127621375,-0.205958755,1.540928459,2.447448777,-4.570665341,-4.335074066,-5.41764975,-3.269036613,-5.129985802,-4.701580475,-4.955573663,-1.558094527 -1913,A124R,-0.021502245,-1.450598755,-1.849036898,-2.212339794,-2.826507129,0.048507135,-0.005208739,-0.03779575,0.002319788,-1.551848695,-1.349348814,-1.744142921,-1.953930875,-1.819635461,-2.605044127,-2.812034086,-2.840980172,0.057161815,-0.940397344,-12.76864804,-12.83098136,-13.31063694,-10.02874359,-11.69906257,-15.97381574,-9.484012134,-6.960656187 -1914,A124T,0.000719217,0.02123136,-0.007647773,0.021103466,-0.065903937,0.029218228,-0.006012639,0.007451073,0.139440997,0.066929433,-0.024466713,0.009987303,-0.025282849,0.042784322,-0.00057739,-0.032283877,-0.099523996,1.270488892,2.533330658,-2.155634737,-2.22340197,-4.019852142,-0.367877304,-1.877604225,-2.289438042,-3.405556116,-0.809660258 -1915,A124W,-0.015929685,-1.538998013,-1.721842384,-1.871475424,-3.152292824,0.042997717,-0.00702903,-0.024830339,-0.074706783,-1.604930001,-1.473066024,-1.56579186,-1.877892908,-1.697400341,-2.045550507,-2.773345018,-3.531240629,3.990469557,1.77616925,-15.122767,-15.23706037,-17.13106564,-12.85037509,-13.47403239,-16.92130152,-10.31777227,-9.781868041 -1916,A124V,-0.018007089,0.052014685,0.016972908,0.030278532,-1.107471463,0.019667097,0.007737874,-0.043752052,0.023896711,0.078667489,0.025361881,0.029620783,0.004325033,0.080564472,-0.020007408,-0.84262122,-1.372321706,0.109416613,1.317462885,-7.77839187,-9.537791603,-9.901490677,-5.698830536,-7.175420654,-6.57842588,-6.679351416,-3.792301065 -1917,A124Y,0.107512755,-1.657628385,-2.063686512,-1.918772045,-2.822925611,0.039033983,0.13006011,0.0849654,-0.02596662,-1.505071973,-1.810184796,-2.013636161,-2.113736862,-1.844214647,-1.993329442,-2.698310574,-2.947540647,3.666191181,1.30648619,-16.2577343,-15.79048249,-17.97996777,-14.38175153,-14.37147392,-18.76499578,-10.31777227,-9.781868022 -1918,I125A,-0.066218315,-0.02517663,-0.03068767,-1.371419929,-2.202247019,-0.006927925,0.065395883,-0.197832512,-0.186011717,-0.097745277,0.047392018,-0.07909796,0.01772262,-1.062871417,-1.67996844,-2.392808387,-2.01168565,1.151955893,0.827712644,-9.632787195,-10.4586629,-11.85987718,-7.99991008,-7.784791779,-10.06069404,-7.133038135,-4.038124583 -1919,I125C,-0.085918485,0.023420327,-0.02902827,-0.040319375,-0.968433878,-0.049620543,0.014301577,-0.186138547,-0.17057713,-0.017195359,0.064036013,-0.020493871,-0.037562669,-0.029334441,-0.051304309,-0.93943662,-0.997431135,0.723755284,1.366460799,-12.67294516,-13.83719751,-14.60306833,-11.87865926,-11.53440368,-11.51139702,-8.706265344,-6.381182717 -1920,I125E,-0.087453285,-0.759172385,-2.04802089,-2.212835244,-2.822332951,0.029572399,0.07154856,-0.246455129,-0.140257257,-0.68500464,-0.83334013,-2.230979969,-1.86506181,-1.953431069,-2.472239418,-2.862198189,-2.782467712,1.17711777,-0.343828657,-13.15275744,-13.3660434,-13.57445417,-12.06144122,-12.95555928,-13.80628915,-8.472607369,-5.290135811 -1921,I125D,-0.043250388,-1.23294631,-1.846684855,-2.297547593,-2.81996692,-0.009370877,0.084816478,-0.171317254,-0.089828108,-1.114677691,-1.351214928,-2.017200344,-1.676169366,-2.089899462,-2.505195723,-2.426569814,-3.213364026,3.498822347,1.287207296,-15.45085988,-15.85219949,-16.96023816,-14.21911049,-15.23976995,-14.9829813,-10.44602202,-9.899372265 -1922,I125G,-0.085113422,-0.623324248,-1.721466368,-2.114614389,-2.841845031,0.006625474,0.052978254,-0.223205098,-0.121121347,-0.596861318,-0.649787177,-1.770678779,-1.672253956,-1.991041448,-2.238187329,-2.836465903,-2.847224159,3.141818627,1.252099801,-13.67901249,-12.22365531,-15.41863157,-13.0977311,-13.47898462,-14.17605985,-8.260474514,-4.271797873 -1923,I125F,-0.089519974,-0.046757141,-1.39250929,-2.344657527,-2.759572193,0.002825681,0.045280693,-0.22432064,-0.129425461,-0.126160335,0.032646054,-1.231258614,-1.553759966,-2.261205752,-2.428109302,-2.801996087,-2.717148298,1.253027147,0.179864806,-13.29175462,-14.14558376,-12.92468789,-13.18209433,-13.44737045,-12.75903665,-10.21122244,-8.727994678 -1924,I125H,-0.064018194,-0.033090676,-0.173043181,-1.724238004,-2.754127506,0.030696402,0.108618837,-0.236655225,-0.298766759,-0.078460254,0.012278903,-0.149246531,-0.19683983,-1.484757727,-1.96371828,-2.183155915,-3.325099097,1.124195569,0.742497521,-15.34487425,-15.44721692,-15.85189713,-14.75411645,-14.92171118,-15.74942957,-10.44602202,-9.899372265 -1925,I125K,-0.108951371,-1.548533099,-2.170276038,-2.170831092,-3.266314437,0.041149222,0.022168692,-0.240071433,-0.161993653,-1.470494494,-1.626571704,-2.163757524,-2.176794551,-2.090328607,-2.251333576,-2.87415699,-3.658471883,0.448169435,-0.92653349,-14.17258681,-14.86128167,-14.02128481,-12.82601785,-13.89949456,-15.25485519,-10.44602202,-9.899372265 -1926,I125M,-0.087404217,-0.002178768,-0.020846169,-0.073686246,-0.156435923,-0.050391452,0.015575136,-0.19038357,-0.090435977,-0.052232374,0.047874839,-0.057767403,0.016075066,-0.053883256,-0.093489236,-0.166106878,-0.146764968,1.479126336,2.235439682,-4.692622585,-5.405469399,-4.86990049,-2.79810006,-4.525911736,-5.863731239,-5.04142236,-1.304348636 -1927,I125L,-0.059889111,0.001477955,-0.00032826,-0.010313168,-0.138641855,0.005385777,0.062754299,-0.18253252,-0.177111928,-0.05877724,0.061733149,-0.028143223,0.027486703,-0.011568446,-0.00905789,-0.146620074,-0.130663636,1.458762804,2.272174879,-4.374294254,-5.128769363,-4.159971283,-4.483471321,-4.140386772,-3.958872528,-4.172423375,-0.812654203 -1928,I125N,-0.05297929,-0.026202272,-0.065629432,-1.740376481,-3.007071167,-0.019573786,0.085101654,-0.191060233,-0.23904744,-0.12019612,0.067791576,-0.068528717,-0.062730147,-1.40715287,-2.073600092,-2.864397153,-3.14974518,1.294871011,0.797201422,-12.69898209,-13.0122295,-15.21546893,-11.76786314,-12.2676311,-11.23171778,-7.93265264,-5.756676117 -1929,I125Q,-0.113961714,-0.037409148,-0.998846248,-2.025853157,-3.349302481,0.039589344,0.013010218,-0.240933645,-0.164622079,-0.12220702,0.047388724,-0.853646807,-1.144045688,-1.698423028,-2.353283286,-3.114274626,-3.584330335,2.308399774,1.070785477,-11.77680745,-11.6231824,-11.03226245,-10.88130802,-11.8924221,-13.45486229,-7.345021974,-3.634575228 -1930,I125P,-0.077798854,-1.476659216,-1.927895247,-2.247869636,-3.005934819,0.00434125,0.056781372,-0.212379079,-0.208805606,-1.632662926,-1.320655505,-1.973743438,-1.882047055,-2.252497039,-2.243242233,-2.668348637,-3.343521001,0.151369032,-1.067627717,-14.54948802,-15.40013929,-16.18685442,-13.32877854,-13.75698258,-14.07468529,-10.44602202,-9.899372265 -1931,I125S,-0.048179437,-0.007946613,-0.209213757,-1.773380575,-2.537780242,0.016205812,0.096695553,-0.193054427,-0.162343697,-0.095183052,0.079289826,-0.183281055,-0.235146458,-1.428665184,-2.118095966,-2.629507457,-2.446053027,1.291391193,0.791153126,-11.52292218,-12.04883678,-15.11985659,-10.38802359,-10.16480795,-9.893085968,-7.228587276,-5.227952484 -1932,I125R,-0.092362957,-1.493834196,-2.040137092,-2.409636181,-3.247099866,0.049311093,0.061986396,-0.246712309,-0.194976603,-1.505721913,-1.481946478,-1.948647656,-2.131626527,-2.215166801,-2.604105561,-2.880895872,-3.61330386,-0.038773228,-1.170002506,-14.90523118,-15.27754626,-15.35742747,-13.56438597,-14.0873095,-16.2394867,-10.44602202,-9.899372265 -1933,I125T,-0.022518601,0.047943911,-0.002759289,-0.006095357,-1.533516229,0.011945543,0.112718697,-0.157755898,-0.057020278,-0.001361569,0.097249391,-0.017622213,0.012103635,-0.018069937,0.005879223,-1.595489167,-1.47154329,0.692557534,1.315981425,-7.983609261,-9.702725815,-10.37699564,-6.019796539,-6.819969376,-6.998558929,-6.17068232,-2.938651027 -1934,I125W,-0.089261049,-1.627393401,-2.172661274,-2.345992298,-3.393020637,-0.026331027,0.055831031,-0.234353129,-0.205165576,-1.813988185,-1.440798617,-2.008940661,-2.336381887,-2.287694262,-2.404290333,-2.895431387,-3.890609886,0.040009434,-1.139187731,-14.6480406,-15.63006039,-14.81217919,-13.83116146,-14.26786879,-14.69893316,-10.44602202,-9.899372265 -1935,I125V,-0.038372133,0.009569357,-0.019422379,-0.039457358,-0.082027902,-0.048501436,0.089431239,-0.166175504,-0.105345494,-0.073285006,0.092423719,-0.054879248,0.016034491,-0.0485214,-0.030393315,-0.098407374,-0.06564843,1.368838123,2.337927221,-2.047635144,-2.035675507,-2.351994377,-2.005875168,-1.839871872,-2.004758797,-4.110159854,-0.643668394 -1936,I125Y,-0.068701061,-1.252592752,-1.808803546,-2.245651922,-3.116589002,0.035697628,0.096579893,-0.233982014,-0.088170845,-1.403368945,-1.101816558,-1.853593927,-1.764013165,-2.266241107,-2.225062736,-2.630940183,-3.60223782,3.386721034,1.070588895,-14.89165804,-15.6022628,-15.16128007,-14.22550773,-14.67087075,-14.79836886,-10.44602202,-9.899372265 -1937,T126A,-0.176673497,0.02516144,0.011372337,0.007038443,-0.120109387,-0.028940865,-0.034777551,-0.318569442,0.005589882,0.003542361,0.046780518,-0.018008764,0.040753438,-0.018139434,0.03221632,-0.123161907,-0.117056866,1.375031762,2.206857663,-5.793117514,-4.99081427,-5.499103188,-6.02096032,-5.733378197,-6.721331596,-4.146223913,-1.442800317 -1938,T126C,-0.170671271,0.053424704,0.021207442,0.034808559,-0.180494208,0.051298663,-0.014465132,-0.32687741,-0.066769418,-0.022129307,0.128978714,-0.025209718,0.067624601,-0.044825861,0.114442978,-0.273467589,-0.087520826,1.201224261,1.838521692,-11.10441903,-9.374317329,-11.53553254,-12.0258579,-12.34781847,-10.23856892,-6.724662151,-3.430291763 -1939,T126E,-0.226593963,0.011359515,-0.011120608,-0.021424414,-0.021148683,-0.04611073,-0.069677933,-0.383509993,-0.106197796,0.036863446,-0.014144417,0.003948511,-0.026189726,-0.021818247,-0.02103058,-0.001614933,-0.040682433,1.242359974,2.550598346,-7.436071938,-6.285330719,-5.827951118,-6.75056414,-10.29507455,-8.021439163,-4.458323879,-2.018964078 -1940,T126D,-0.135070456,0.030407816,0.016024766,0.033439849,-1.327968144,0.021901772,0.034626233,-0.304767145,0.089156158,-0.025161897,0.085977529,-0.069127378,0.10117691,-0.017465956,0.084345654,-1.079401729,-1.576534558,0.662473875,1.344273693,-8.294395634,-6.775618446,-9.668968216,-7.239932098,-11.0876373,-6.699822113,-4.614884053,-2.883381151 -1941,T126G,-0.202658918,0.025132771,-0.008218524,-0.03074706,-0.090434344,-0.034886636,-0.033319194,-0.371998641,-0.064718377,-0.030806115,0.081071656,-0.055496355,0.039059308,-0.07495613,0.013462011,-0.133608651,-0.047260036,1.359925915,2.159530468,-9.182486665,-7.142824554,-7.994976532,-10.2340385,-10.91756342,-9.623030327,-5.753374696,-2.944078448 -1942,T126F,0.006165254,-0.004701082,-0.168111795,-2.150199067,-2.757769654,0.074592284,0.038144394,-0.025813886,-0.189879544,-0.036298263,0.026896099,-0.22621001,-0.11001358,-1.773063661,-2.527334472,-2.702180749,-2.813358559,1.259639343,0.727886002,-14.08599279,-11.66260291,-13.55068627,-16.27610898,-17.7742057,-11.16636011,-8.276247201,-6.721168063 -1943,T126I,0.054975047,0.030746958,-0.041504527,-0.054540511,-0.628457424,-0.080044696,-0.040493251,0.150443344,0.088874057,-0.011003442,0.072497358,-0.020602716,-0.062406338,-0.040973498,-0.068107524,-0.49116353,-0.765751317,0.940488928,1.525378031,-7.728511931,-6.148190926,-9.093715935,-9.060529358,-10.13842004,-4.2017034,-4.497360546,-0.889531709 -1944,T126H,-0.239146334,0.063781465,-0.004860651,-0.001251264,-1.590108896,-0.058663825,-0.055126302,-0.423166366,-0.033648449,0.025202891,0.102360039,-0.001900662,-0.00782064,0.025630136,-0.028132663,-1.597736318,-1.582481473,0.569519494,1.308740624,-12.44205402,-11.35238619,-9.833808563,-11.49268142,-14.26170677,-15.26968714,-6.877052542,-4.659106153 -1945,T126K,0.01733511,0.023398911,0.011957141,-0.030240171,-1.358378399,-0.064843736,0.016390416,0.018279804,-0.292541885,-0.0272154,0.074013222,-0.01196888,0.035883161,-0.03820093,-0.022279411,-1.240962213,-1.475794585,0.909367062,1.360252077,-11.04969965,-9.591318314,-8.981144516,-10.27202608,-12.63486887,-13.76914048,-6.343623046,-3.013720441 -1946,T126M,-0.115175431,-0.007546683,-0.061007772,-0.098493584,-0.243990837,-0.043653135,-0.125839763,-0.104511098,-0.252931289,-0.002569797,-0.012523568,-0.036320395,-0.085695149,-0.048807859,-0.148179308,-0.233580259,-0.254401415,1.421229036,2.038108655,-10.56531313,-9.569071037,-10.97642991,-11.91582149,-12.64020019,-7.725043007,-6.354604851,-3.815295743 -1947,T126L,-0.096693993,0.035541718,-0.010968824,0.001030416,-0.861657724,-0.046596676,0.023362429,-0.216750415,0.001598959,-0.018677819,0.089761254,-0.050693495,0.028755847,-0.018561561,0.020622392,-0.705767945,-1.017547503,0.868131709,1.432941006,-10.14548396,-9.405060966,-10.9931811,-9.426929031,-12.99801671,-7.904231979,-4.988605195,-3.096857965 -1948,T126N,-0.009998497,0.047442564,0.009316461,0.018008129,-1.293054109,-0.055926693,-0.022355494,0.0023585,-0.083826151,-0.007764649,0.102649776,-0.054309467,0.072942389,0.006685216,0.029331042,-1.366694596,-1.219413622,0.65737133,1.323494795,-9.602508217,-8.343792046,-7.808517845,-9.491787117,-12.49008698,-9.878357101,-6.957415086,-4.135898254 -1949,T126Q,-0.278037364,0.003320018,-0.032037934,0.001074634,-0.287981456,0.002231299,-0.091466291,-0.464608436,-0.197389145,-0.051920839,0.058560875,-0.018034438,-0.046041429,-0.0133555,0.015504768,-0.241967972,-0.333994939,1.582549604,2.193047553,-9.394827292,-8.883511459,-7.265637672,-8.392173203,-10.37076799,-12.06204613,-5.249534717,-1.257722168 -1950,T126P,-0.05767008,0.01881771,-0.764687577,-1.751438869,-2.750667125,0.013981713,-0.040171266,-0.075168893,-0.124526497,-0.017884181,0.055519601,-0.54003178,-0.989343374,-1.614170982,-1.888706756,-2.651114497,-2.850219752,1.948731041,0.975242986,-12.96601012,-12.04315368,-12.60910185,-13.01417787,-13.8056789,-13.35793828,-9.77976323,-9.131236502 -1951,T126S,0.118173502,0.05207628,-0.03551794,-0.02157785,-0.028377464,-0.011246935,0.018914724,0.217432279,0.006415102,-0.027350463,0.131503022,-0.078035257,0.006999378,-0.052973375,0.009817675,-0.099893766,0.043138839,1.489049856,2.394101586,-4.383847255,-3.326948158,-3.611209122,-5.142260109,-5.062231842,-4.776587044,-4.611230074,-0.964335235 -1952,T126R,-0.194517857,0.020742066,-0.001751331,0.018190034,-1.419410018,-0.079218402,-0.041646191,-0.347389523,-0.069441308,-0.02500302,0.066487152,-0.018821307,0.015318645,-0.008552751,0.044932819,-1.40808033,-1.430739705,0.499793701,1.315191444,-9.796206619,-10.33786086,-5.930782623,-9.140552422,-9.848872414,-13.72296478,-4.130640631,-0.929608928 -1953,T126W,-0.229082489,0.027459781,0.001245004,-1.305275812,-1.963531436,0.048581084,-0.042909648,-0.41525533,-0.123244635,0.022612826,0.032306736,-0.015261059,0.017751066,-1.024162661,-1.586388963,-2.259704776,-1.667358095,0.825755586,0.761792895,-15.30228653,-13.22078146,-15.85339976,-16.18777871,-16.1401834,-15.1092893,-7.452526696,-5.571198613 -1954,T126V,-0.198466409,0.0203496,-0.014448074,-0.037117988,-0.382375273,-0.029002661,-0.036838408,-0.36009441,-0.002015291,-0.02119364,0.061892839,-0.030851514,0.001955366,-0.061134528,-0.013101448,-0.296762893,-0.467987653,1.318634597,1.90821595,-7.150633237,-5.983161682,-7.573802505,-8.561071411,-8.021590378,-5.613540207,-4.781519003,-1.305373847 -1955,T126Y,-0.29396024,0.04063387,-0.037705083,-1.398911126,-2.701306344,0.010168302,-0.115741942,-0.472178537,-0.114977095,0.001442949,0.07982479,-0.052002895,-0.023407271,-0.901601926,-1.896220326,-2.983007358,-2.419605329,0.807378155,0.776088719,-13.65478704,-10.7361521,-12.05254279,-15.80411532,-16.49321675,-13.18790826,-7.270115588,-5.048094289 -1956,M127A,0.737219997,0.029317033,-0.071418003,-0.062722619,-0.692690836,-0.063705055,-0.021008381,1.495448375,,-0.003451865,0.062085931,-0.014806191,-0.128029814,-0.003512012,-0.121933226,-0.396513433,-0.988868238,1.035528788,1.629259898,-7.082077161,-6.745081833,-7.523826004,-7.563333618,-7.471268532,-6.106875816,-6.542859728,-1.391320006 -1957,M127C,0.118574378,-0.018297834,-0.040678448,-0.017391625,-0.486946733,-0.009454121,-0.058265174,0.29541393,,-0.017858406,-0.018737262,-0.046946969,-0.034409926,-0.030666684,-0.004116566,-0.33115668,-0.642736786,1.2766628,1.833436851,-10.58717039,-9.447184036,-10.43770061,-10.76744659,-10.96046327,-11.32305745,-8.76576791,-4.460167805 -1958,M127E,0.096189551,-0.016611354,-0.014242088,-0.024533059,-0.163903742,-0.032680028,-0.066912568,0.259291669,,0.046085136,-0.079307844,0.01576864,-0.044252816,-0.007480884,-0.041585234,-0.051374002,-0.276433481,1.16497741,2.371227882,-7.552246408,-6.871036591,-7.586551071,-8.248684227,-8.113047348,-6.941912804,-5.627922491,0.517089235 -1959,M127D,1.093056988,-0.095966797,0.166986457,0.200758563,-0.936038974,-0.036453617,0.213074825,1.97303915,,0.060374433,-0.252308026,0.036033994,0.297938919,0.003577117,0.397940009,-0.786299696,-1.085778251,0.725158678,1.386158154,-10.60666189,-9.163905205,-13.4295986,-10.29794485,-9.984998222,-10.15686257,-6.516256971,-0.403004927 -1960,M127G,0.315820581,0.021604144,-0.01518756,0.024761447,-1.497130957,-0.039307939,0.017019044,0.614622118,,0.052876664,-0.009668376,0.00601708,-0.036392199,0.040351931,0.009170963,-1.476338693,-1.517923221,0.644506104,1.31673331,-10.35471973,-9.279828117,-9.760237656,-10.46521534,-11.24045035,-11.02786718,-7.60840406,-3.098645173 -1961,M127F,-0.036729682,0.009536845,-0.004058365,0.00638292,-0.309422693,-0.006582265,-0.048754268,-0.024705096,,0.027334384,-0.008260694,0.062983416,-0.071100145,0.056641227,-0.043875388,-0.149390382,-0.469455004,1.365587543,2.22789784,-7.190203957,-5.756568871,-6.985108963,-7.212079796,-8.330140434,-7.667121719,-4.912420187,-0.339359106 -1962,M127I,0.081591538,0.010909596,-0.002834962,-0.003803299,-0.126323898,0.00738454,-0.022330435,0.18551351,,-0.017562752,0.039381943,-0.011722225,0.006052302,0.013294038,-0.020900635,-0.110721739,-0.141926057,1.386294276,2.307707135,-3.579996756,-3.063875626,-3.282390732,-3.177001747,-5.009045853,-3.367669823,-4.299826274,0.768950719 -1963,M127H,-0.1267838,-0.002129527,-0.014032139,-0.00283735,-0.7132525,0.003345148,-0.012621744,-0.240945855,,0.018526128,-0.022785182,-0.028887146,0.000822869,-0.028932893,0.023258193,-0.563783551,-0.862721449,0.965565392,1.511370007,-8.453265498,-5.756870308,-9.507846596,-8.982190681,-10.25468877,-7.76473114,-6.202551862,0.11060269 -1964,M127K,-0.030666195,0.003829456,0.04983254,0.022735163,-0.578754318,-0.075655068,-0.015807187,-0.045525202,,-0.004224813,0.011883725,0.04525503,0.054410049,0.039408291,0.006062035,-0.311014784,-0.846493851,0.958549892,1.656834925,-6.888286641,-6.14394117,-6.855686172,-7.764972649,-8.718545753,-4.95828746,-5.725738405,-0.401553496 -1965,M127L,-0.219845667,0.011461458,0.01146416,0.040917756,0.005314044,-0.023096678,-0.031636807,-0.408054526,,-0.003082868,0.026005783,0.022139267,0.000789053,0.011718675,0.070116836,0.014403937,-0.00377585,1.197901555,2.649089193,-1.70865825,-0.873971176,-2.149725998,-1.460585167,-2.358745293,-1.700263618,-3.55071335,1.061192272 -1966,M127N,0.191001723,0.046361299,0.031755263,0.047141745,-0.767545404,-0.01430906,-0.071141671,0.453145116,,0.090711564,0.002011033,0.06375376,-0.000243234,0.092857233,0.001426256,-0.536981912,-0.998108895,0.521351368,1.386103663,-8.887957298,-8.440184196,-9.246274239,-9.206233192,-8.959856293,-8.587238571,-6.276364739,-1.171991946 -1967,M127Q,-0.256329327,0.027999579,-0.013879313,0.016574106,-0.108822238,-0.098266145,-0.041613344,-0.47104531,,0.019542022,0.036457136,-0.033220814,0.005462189,0.014994394,0.018153817,-0.091217104,-0.126427372,1.354363382,2.335204358,-4.675554074,-4.319172379,-4.351906929,-4.466376358,-5.373686371,-4.866628334,-4.433604645,0.9273366 -1968,M127P,-0.127984832,-0.351675808,-1.493384021,-2.107462107,-2.891893956,-0.01092818,-0.047526513,-0.20844315,,-0.262528681,-0.440822935,-1.528500962,-1.45826708,-2.017809133,-2.197115081,-2.960287068,-2.823500844,2.638841342,0.991786266,-11.22992623,-10.30533861,-11.53219071,-10.91125205,-12.19764767,-11.20320213,-9.761802929,-6.678452117 -1969,M127S,0.132158108,0.026204992,-0.003291215,0.023630271,-0.556848646,-0.041976245,0.007931769,0.256384446,,0.036167568,0.016242416,-0.010460487,0.003878058,0.021432809,0.025827733,-0.368013059,-0.745684233,1.118565946,1.696697495,-7.777274414,-7.290417068,-6.921976044,-7.700675667,-7.959889488,-9.013413803,-6.126012405,-1.562331719 -1970,M127R,-0.142308791,0.024092656,-0.005452492,0.042037901,-0.219904281,-0.047286936,-0.042897913,-0.241719669,,0.029194595,0.018990717,0.027573353,-0.038478337,0.023910644,0.060165157,-0.099496826,-0.340311735,1.452904773,2.433234466,-6.314464351,-5.060274757,-6.377533348,-6.212635727,-8.903704277,-5.018173645,-4.621488605,0.517028536 -1971,M127T,0.324975026,0.021246325,-0.049599325,0.010079181,-0.084530918,-0.046856847,-0.050166609,0.700116661,,0.049206443,-0.006713793,0.025256704,-0.124455353,0.035222108,-0.015063746,0.007832779,-0.176894614,1.187722774,2.755023382,-3.700639127,-5.050727287,-3.180319046,-3.347124123,-3.42329026,-3.501734917,-3.860493344,0.402649468 -1972,M127W,-0.152195719,0.022023213,-0.008344155,0.029861026,-0.060863436,0.015350743,-0.049791455,-0.254599983,,0.027360687,0.016685738,0.032160259,-0.048848568,0.056516911,0.00320514,-0.034595375,-0.087131496,1.432655598,2.691098977,-6.262713083,-5.540571922,-4.178261131,-5.468853989,-7.24382608,-8.882052292,-4.823903016,-0.820240052 -1973,M127V,0.250143235,-0.008310552,-0.054514981,-0.024613634,-0.026401494,0.00533881,-0.035189453,0.535475923,,0.021807103,-0.038428206,-0.001297976,-0.107731985,0.006691671,-0.055918938,0.02048114,-0.073284127,1.175981933,2.606005258,-3.392381737,-2.669580376,-3.321936333,-3.078908966,-4.130944603,-3.760538406,-2.507058966,1.567671189 -1974,M127Y,-0.067259759,-0.031946522,-0.067888971,-0.029167728,-0.200429175,-0.000187081,-0.084796651,-0.049722866,,-0.03564714,-0.028245903,-0.045668754,-0.090109188,-0.04177736,-0.016558095,-0.116378629,-0.284479721,1.441274791,2.315629562,-6.819694019,-5.883712425,-6.485792641,-6.890903542,-7.85604039,-6.982021095,-4.395572628,1.420604319 -1975,S128A,0.016472111,-1.251564531,-2.236337372,-2.114316659,-2.873953259,-0.109012917,-0.061603724,0.094547946,0.049411861,-1.320551154,-1.182577908,-1.993783158,-2.478891585,-2.178191303,-2.050442014,-2.764059806,-2.983846711,0.18561698,-0.78568327,-9.651037715,-9.803297722,-9.69631546,-9.449031242,-9.864269669,-9.442274483,-8.776495975,-9.732748318 -1976,S128C,-0.111404958,-1.607611267,-1.99094189,-2.097380111,-2.662433669,-0.025056216,-0.032390652,-0.190419264,-0.113106591,-1.568578542,-1.646643992,-1.675748208,-2.306135572,-1.773006176,-2.421754045,-2.212746644,-3.112120693,4.218314565,1.979290392,-9.95241906,-9.875566727,-10.08568948,-9.893529465,-10.11184448,-9.795465149,-9.022567354,-11.21585505 -1977,S128E,-0.155754129,-1.722686105,-1.812883866,-2.653002795,-3.20795466,-0.06953229,-0.072499727,-0.239008531,-0.200108315,-1.869608537,-1.575763673,-1.800686944,-1.825080787,-2.462216343,-2.843789247,-3.18278342,-3.2331259,-0.214970295,-1.170388274,-9.919787149,-10.02295014,-9.929194016,-9.915491486,-10.04593493,-9.685365173,-9.055072442,-11.57519656 -1978,S128D,-0.074296849,-1.719326006,-2.278747888,-2.190200569,-2.807621802,-0.135373257,-0.0232954,-0.125298297,0.196626992,-1.853061984,-1.585590027,-2.011384173,-2.546111602,-1.718671062,-2.661730075,-2.564176876,-3.051066727,-0.763637959,-1.043867321,-7.99417059,-8.391711548,-8.263399506,-7.706575043,-7.842781822,-7.766385033,-7.402024052,-7.494333591 -1979,S128G,-0.092305688,-0.033182848,-0.455678036,-1.742475941,-2.500924977,-0.102192718,-0.035967221,-0.148644154,-0.067659977,-0.040500689,-0.025865006,-0.417595147,-0.493760925,-1.5925274,-1.892424481,-2.564014674,-2.437835279,2.098901439,1.091643583,-5.303970528,-5.612216721,-5.315092239,-5.02618837,-5.510173515,-5.056181793,-5.463115737,-5.023569633 -1980,S128F,-0.118576521,-1.498525991,-2.026254384,-2.565343318,-2.881734555,0.03679083,0.0053828,-0.242535842,-0.020923978,-1.761539567,-1.235512415,-1.986808545,-2.065700222,-2.472246685,-2.65843995,-2.715692507,-3.047776602,-0.423791943,-1.081604268,-10.01269843,-10.1602113,-10.0693588,-9.854657761,-10.20304729,-9.776217018,-9.055072442,-11.57519656 -1981,S128I,-0.12006068,-1.540195432,-2.122496059,-2.184463738,-3.040445598,0.054247401,-0.045525929,-0.19459543,0.008019176,-1.741955452,-1.338435412,-2.025216376,-2.219775741,-2.033533262,-2.335394214,-3.055130334,-3.025760862,-0.419133913,-1.077378628,-9.969516109,-10.13907819,-9.935002235,-9.822947205,-10.12422798,-9.826324936,-9.055072442,-11.57519656 -1982,S128H,-0.147960892,-1.610025019,-1.850737777,-1.991886702,-3.245808571,-0.052833064,-0.046118051,-0.249803733,-0.064322646,-1.624536319,-1.595513718,-1.798652774,-1.902822779,-1.761212169,-2.222561235,-3.18074925,-3.310867892,-0.099821273,-1.026655084,-9.939668704,-10.15204019,-9.894594437,-9.855421227,-10.04061165,-9.755676018,-9.055072442,-11.57519656 -1983,S128K,-0.112531175,-1.769479075,-2.201264704,-2.024671756,-2.380653616,-0.069100745,-0.069917138,-0.155145211,-0.302770657,-1.773036628,-1.765921521,-1.931358817,-2.471170591,-1.939675702,-2.109667809,-2.48415152,-2.277155712,-0.146076705,-1.13638157,-9.968428607,-10.10179744,-9.99029126,-9.926438393,-10.05288853,-9.770727417,-9.055072442,-11.57519656 -1984,S128M,-0.198782875,-1.511314354,-2.049144439,-2.088233373,-2.754109612,-0.010537799,-0.068827006,-0.328738744,0.077440584,-1.549494721,-1.473133986,-2.054604395,-2.043684482,-2.01716379,-2.159302955,-2.959579617,-2.548639607,-0.419966313,-0.969827264,-9.94414164,-10.13962422,-9.847012901,-9.833991989,-10.12719598,-9.772883102,-9.055072442,-11.57519656 -1985,S128L,-0.184526395,-1.505193686,-1.877270638,-2.309419662,-3.014886525,0.066557233,-0.077642374,-0.291410416,0.014258994,-1.608770369,-1.401617002,-2.054758592,-1.699782684,-1.90034818,-2.718491144,-3.046883989,-2.98288906,-0.232805206,-1.010719535,-9.981570526,-10.31303664,-9.966659691,-9.867466385,-10.06143769,-9.69925222,-9.055072442,-11.57519656 -1986,S128N,-0.081474372,-1.548084941,-1.979870571,-2.002247627,-2.858229487,-0.090487505,-0.039080575,-0.123868169,0.082724532,-1.52626488,-1.569905002,-1.985617064,-1.974124077,-1.914752703,-2.08974255,-2.63531978,-3.081139194,-0.20482735,-0.93529136,-7.36925621,-7.715035149,-7.47119458,-7.370648468,-7.002819092,-7.286583763,-6.928677438,-6.962839144 -1987,S128Q,-0.102006272,-1.870261559,-1.864516557,-2.548003261,-2.952440127,-0.045123679,-0.009388637,-0.194623907,-0.06795693,-1.841463832,-1.899059286,-1.969822797,-1.759210316,-2.376079691,-2.71992683,-2.795616772,-3.109263482,-0.371519928,-1.097881519,-9.926672137,-10.12087891,-10.04599197,-9.686287682,-10.1490668,-9.63113533,-9.019885811,-11.1932423 -1988,S128P,-0.039479091,-1.35787052,-1.96086749,-2.232399823,-3.027514885,0.023319289,-0.043320909,-0.035637272,-0.052150165,-1.369708446,-1.346032594,-2.007981179,-1.9137538,-2.192389323,-2.272410322,-2.967314063,-3.087715706,0.400492443,-0.828949044,-10.01514559,-10.14841965,-10.06400735,-9.807408493,-10.20840218,-9.847490257,-9.055072442,-11.57519656 -1989,S128R,-0.121325317,-1.509393283,-2.037273473,-2.214769528,-3.158797018,0.002808129,-0.052069072,-0.190581562,-0.083004859,-1.574435654,-1.444350911,-2.1669991,-1.907547846,-2.018192566,-2.41134649,-2.562668384,-3.754925652,0.096084474,-1.004895278,-9.787155513,-9.869352928,-9.948300484,-9.655300156,-9.939381119,-9.523442879,-8.941397564,-10.52730727 -1990,S128T,-0.068305479,-0.33444885,-1.458091985,-2.090616501,-2.404437919,0.099437219,-0.075720714,-0.060890244,-0.021153703,-0.248630202,-0.420267497,-1.49841133,-1.417772639,-2.028053132,-2.15317987,-2.187178069,-2.621697768,3.851672414,2.192045554,-7.460366035,-7.415571739,-7.518218643,-7.191391609,-7.696567062,-7.480081123,-7.55595057,-7.055243389 -1991,S128W,-0.16198607,-1.636322283,-2.13909395,-2.161471007,-2.804468501,0.058580403,-0.045422903,-0.278549237,0.031782373,-1.520071792,-1.752572774,-1.917276069,-2.360911831,-2.022502968,-2.300439045,-2.442040049,-3.166896952,-0.068443512,-0.932007817,-10.05523192,-10.26997732,-10.09023405,-9.873014656,-10.24041226,-9.802521324,-9.055072442,-11.57519656 -1992,S128V,-0.158187015,-1.438201099,-1.719471731,-1.883499401,-2.980611709,0.058885986,-0.033843865,-0.282530165,-0.038957406,-1.477046857,-1.399355341,-1.70595012,-1.732993341,-1.944715927,-1.822282875,-2.519154968,-3.442068449,4.011122061,1.765720587,-9.925436668,-10.07316266,-10.0028512,-9.678073425,-10.110121,-9.76297506,-9.055072442,-11.57519656 -1993,S128Y,-0.178490725,-1.687942789,-2.397879669,-2.426373953,-3.014799212,0.009939689,-0.087555083,-0.269426367,-0.122314593,-1.642998485,-1.732887093,-2.102350669,-2.693408668,-2.043720765,-2.809027141,-2.831234631,-3.198363793,-0.030194924,-1.046942645,-10.06943672,-10.17239769,-10.11911286,-9.94016629,-10.20241505,-9.913091698,-9.055072442,-11.57519656 -1994,D129A,-0.011829944,-1.408450114,-2.601650206,-2.009108856,-2.712578003,0.055625159,-0.018910208,-0.00474968,-0.262690485,-1.591538649,-1.225361578,-2.363404775,-2.839895637,-1.946800443,-2.071417269,-2.588533139,-2.836622867,0.171758541,-1.122244889,-10.56151826,-11.8151782,-10.32455698,-10.95312377,-10.79195688,-8.922775459,-7.463094196,-6.754707786 -1995,D129C,-0.003840441,-0.365948412,-1.459399925,-1.84969456,-2.466085328,0.124836252,0.023317966,-0.030998848,-0.305725117,-0.386222262,-0.345674561,-1.566328354,-1.352471495,-1.994822061,-1.704567059,-2.365487985,-2.56668267,3.682378179,1.927697999,-10.97343627,-12.81853464,-10.19605974,-13.16457985,-9.489097267,-9.198909843,-7.172606021,-5.776755163 -1996,D129E,-0.024722138,-0.437193203,-1.567348702,-1.853781284,-2.504882756,0.064984523,0.059846614,-0.109290889,-0.179062499,-0.373456915,-0.50092949,-1.43162978,-1.703067624,-1.693792065,-2.013770502,-2.054698152,-2.955067359,3.870388548,2.327016199,-9.535917332,-10.44951384,-9.203647354,-9.52667952,-9.179198402,-9.320547546,-7.791659991,-7.043508258 -1997,D129G,-0.058882459,-1.106114618,-1.809724632,-2.14584953,-3.150348673,0.088618121,-0.002582539,-0.115182378,-0.385874494,-1.086667358,-1.125561877,-1.830504761,-1.788944503,-2.162088455,-2.129610604,-2.560783103,-3.739914242,3.548114456,1.349180229,-11.2020103,-12.00496219,-10.60032019,-11.85802313,-12.23805478,-9.3086912,-7.689037929,-5.965991002 -1998,D129F,0.053410468,-1.399255522,-2.239057944,-1.958141239,-2.827106995,0.065587057,0.101341547,0.005479389,-0.289550178,-1.366218506,-1.432292538,-2.480507313,-1.997608574,-1.90900102,-2.007281457,-2.881726935,-2.772487055,1.029543282,-0.807698371,-14.74710385,-15.31029925,-13.58688738,-16.80798142,-15.44906331,-12.58128791,-9.671750758,-11.08690701 -1999,D129I,0.121957382,-1.510659399,-2.042749844,-2.111318141,-2.718844525,0.087808753,0.098141432,0.145773331,-0.093117024,-1.394646214,-1.626672583,-1.990421081,-2.095078606,-2.117884793,-2.104751488,-2.868761958,-2.568927091,0.431829843,-0.842943867,-13.67906109,-15.27736082,-12.37789369,-14.26754964,-14.13182085,-12.34068046,-9.671750758,-11.08690701 -2000,D129H,0.109766631,-1.248304497,-1.977182544,-2.196265839,-2.914716598,0.0826177,0.103060645,0.116472616,-0.347542125,-1.483796143,-1.012812851,-2.297054954,-1.657310133,-2.026578657,-2.36595302,-2.999304572,-2.830128623,0.970311973,-0.926067598,-11.32043294,-12.82869043,-10.03161928,-12.63614774,-11.21814159,-9.887565689,-7.693112643,-6.096182003 -2001,D129K,-0.079646051,-1.316888882,-2.209058979,-2.039066649,-2.79710803,0.092081506,-0.025925852,-0.133366249,-0.358431467,-1.462397998,-1.171379766,-2.079362164,-2.338755793,-2.030734617,-2.04739868,-2.781611782,-2.812604278,3.347442364,0.820382676,-12.89603935,-13.73127371,-12.82347176,-13.90686343,-12.62764559,-11.39094226,-8.729112258,-8.173907681 -2002,D129M,-0.005799361,-1.744514476,-2.228149914,-2.296718212,-2.515168971,0.100907186,0.037297117,-0.048895839,-0.236978513,-2.205675426,-1.283353525,-2.102480289,-2.353819539,-2.229944001,-2.363492422,-2.503699912,-2.526638029,-0.098573958,-1.237680814,-13.76827873,-15.37322535,-12.93097838,-14.58922565,-14.17326154,-11.77470274,-9.671750758,-11.08690701 -2003,D129L,-0.023379843,-1.340655327,-1.904621968,-2.177875,-3.197355755,0.098246966,0.019536401,-0.066296086,-0.309047968,-1.387200058,-1.294110595,-1.926752001,-1.882491934,-2.024252489,-2.331497511,-2.996978405,-3.397733105,3.446687315,1.058825631,-14.00906497,-15.46476691,-13.12358035,-14.8103076,-14.30693511,-12.33973488,-9.671750758,-11.08690701 -2004,D129N,0.052958175,-0.867696536,-1.881385657,-2.012423323,-2.770464705,0.050656662,0.020455177,0.085461172,-0.085430195,-0.876132274,-0.859260798,-1.891036449,-1.871734865,-2.143438897,-1.881407748,-2.894316063,-2.646613346,2.945940926,0.912109434,-8.919320782,-8.771351852,-8.27338649,-9.257446548,-10.03939047,-8.255028549,-6.651229801,-5.264599277 -2005,D129Q,0.038189192,-1.385652814,-2.005788889,-2.312917813,-2.920444197,0.094676408,0.095123207,-0.018744824,-0.410593871,-1.553912979,-1.217392648,-2.103930356,-1.907647421,-2.231394068,-2.394441558,-2.982271233,-2.858617161,1.044908728,-1.000397661,-13.91128219,-15.35845213,-13.10743671,-14.05901527,-14.96308458,-12.06842224,-9.632368373,-10.79873915 -2006,D129P,0.017618805,-1.461097837,-1.993188282,-2.333790601,-3.018767965,0.073897677,0.015432444,0.019805165,-0.231091499,-1.574481414,-1.347714259,-1.927218233,-2.05915833,-2.297719993,-2.369861209,-2.80555911,-3.23197682,0.461090977,-1.020253926,-13.65381118,-14.7681695,-12.80506709,-14.36339105,-14.11708393,-12.21534432,-9.608956381,-10.82145565 -2007,D129S,0.011819596,-0.61259896,-1.842474904,-2.4110432,-3.129493959,0.06775876,0.018533021,0.00510617,-0.175096311,-0.616647374,-0.608550545,-2.035896471,-1.649053336,-1.987268923,-2.834817477,-2.959994838,-3.29899308,1.56681955,-0.082826669,-10.57576444,-11.77745882,-10.99855804,-9.922616646,-11.21231445,-8.967874245,-6.371061184,-3.128094537 -2008,D129R,0.028375639,-1.43260327,-2.058856573,-2.12742487,-2.671514636,0.100741895,0.067515669,-0.010764392,-0.425023586,-1.539563953,-1.325642587,-1.964642593,-2.153070553,-2.092106305,-2.162743435,-2.871012194,-2.472017078,3.614472057,1.029570397,-14.2178896,-15.7629626,-13.09037613,-15.42272258,-14.30651825,-12.50686844,-9.671750758,-11.08690701 -2009,D129T,-0.015180192,-1.419740759,-1.994788519,-2.236750559,-2.844276943,0.077110372,0.000484728,-0.030845112,-0.341232651,-1.700994461,-1.138487057,-1.984743948,-2.004833089,-2.061055137,-2.41244598,-2.510902307,-3.177651578,3.845734121,1.195650811,-13.54016954,-15.12629653,-13.28578957,-13.69442089,-13.87408803,-11.7202527,-9.418473075,-9.658783954 -2010,D129W,-0.052357805,-1.337561941,-2.068078843,-2.738707131,-2.957157889,0.071735078,0.012185782,-0.116901392,-0.355725574,-1.339991598,-1.335132283,-2.08958133,-2.046576355,-2.819105033,-2.658309229,-3.092860943,-2.821454835,1.532020746,-0.61031982,-14.21796215,-15.16858621,-12.8766331,-15.66458355,-14.89324905,-12.48675885,-9.671750758,-11.08690701 -2011,D129V,0.013005406,-1.426129434,-1.782516038,-2.035072728,-2.793114109,0.095689849,0.037791967,-0.011781155,-0.30952918,-1.625361775,-1.226897093,-1.782578783,-1.782453292,-2.27801928,-1.792126175,-2.375683931,-3.210544286,0.718500721,-1.028588993,-13.23629935,-15.05665861,-11.9137488,-13.66788264,-13.89113586,-11.65207081,-9.671750758,-11.08690701 -2012,D129Y,-0.004803197,-1.808920774,-1.807537824,-2.060094514,-2.818135896,0.066177267,0.052046555,-0.061652948,-0.600340011,-1.744944588,-1.872896959,-1.574802661,-2.040272986,-2.246334417,-1.87385461,-2.821120324,-2.815151467,3.694833543,0.988652786,-15.01357392,-16.01895072,-14.24526814,-16.98064385,-15.313285,-12.50972189,-9.567958051,-10.36663755 -2013,N130A,0.009842616,0.020782054,-0.395557714,-1.818942451,-2.656971339,-0.093669078,-0.053254894,0.072940125,-0.067322639,0.021797803,0.019766305,-0.352090117,-0.43902531,-1.823558949,-1.814325953,-2.629438273,-2.684504404,1.467109165,0.751625439,-12.98354641,-12.19228654,-11.38029607,-14.21973334,-13.31074714,-13.81466898,-9.806692222,-9.203411388 -2014,N130C,0.024398517,0.109672713,-0.050340777,-0.02844622,-1.746117861,-0.003537146,0.004808529,0.043988505,0.053981812,0.143180268,0.076165157,-0.039203664,-0.06147789,0.007428542,-0.064320981,-1.769877302,-1.722358419,0.753028571,1.310198095,-12.80348507,-12.10647131,-11.4369714,-13.71755447,-13.38781839,-13.36860976,-10.20320526,-11.01779993 -2015,N130E,0.075540251,-0.506865954,-1.962355764,-2.385359875,-2.960183956,-0.013509055,-0.089145342,0.240225844,-0.030693744,-0.400789982,-0.612941926,-1.87104568,-2.053665847,-2.176943011,-2.593776739,-2.890068282,-3.030299629,1.333622985,-0.018033341,-11.29058329,-10.4095993,-10.46944112,-11.5241302,-12.29480589,-11.75493994,-9.128649847,-7.538665372 -2016,N130D,-0.041373187,0.031127541,-0.063908363,-1.266128135,-1.95476231,-0.080367095,-0.074078273,-0.008668101,-0.0641175,0.017088067,0.045167015,-0.036439556,-0.091377169,-0.908558453,-1.623697816,-1.787156007,-2.122368613,2.355137864,1.728763865,-9.102836044,-7.944507446,-8.510061836,-9.471690636,-10.27161156,-9.316308746,-8.196794015,-6.134887279 -2017,N130G,-0.024233236,0.044551976,-0.039669193,-0.46562501,-2.413504986,-0.034404377,-0.05670689,0.008240418,0.134250154,0.077153023,0.011950928,-0.007814877,-0.071523508,-0.374706661,-0.556543358,-2.247677999,-2.579331972,1.423129076,1.320101552,-9.6001627,-9.148767822,-7.414082024,-9.750855118,-11.36770308,-10.31940546,-6.361967029,-3.478570945 -2018,N130F,-0.044510355,-1.682379431,-1.874811332,-2.18077384,-2.968582287,-0.056659869,-0.050862265,-0.038158444,-0.170572831,-2.017103653,-1.347655208,-1.833075828,-1.916546836,-2.205919948,-2.155627732,-2.74295396,-3.194210613,-0.059893058,-1.16293563,-13.17195755,-12.61592044,-12.67158208,-13.22929736,-13.4082211,-13.93476675,-10.20320526,-11.01779993 -2019,N130I,-0.065321569,-1.25755066,-1.725859997,-1.97277285,-3.032615318,-0.012702834,-0.069229559,-0.061413578,0.362698637,-1.258223287,-1.256878032,-1.692897124,-1.75882287,-1.880695143,-2.064850556,-2.961797199,-3.103433437,3.295135625,1.283762523,-13.05782475,-12.07880782,-13.04095367,-14.51217242,-12.72139012,-12.93579974,-9.972288303,-9.640872774 -2020,N130H,0.033708557,-0.845477885,-1.72417433,-2.021344251,-3.198228322,-0.032492802,-0.000551363,0.067968477,0.18607548,-0.891306663,-0.799649107,-1.772247061,-1.676101598,-1.864264572,-2.178423929,-3.179449834,-3.21700681,3.108949663,1.190642147,-9.825878551,-9.0770121,-10.37934066,-9.991969894,-10.5377514,-9.143318703,-8.891296147,-7.847138651 -2021,N130K,0.043483192,-1.357394064,-1.894924006,-1.977307498,-2.376040319,-0.014983327,-0.086058395,0.173024779,0.288065018,-1.263220978,-1.45156715,-1.401412447,-2.388435564,-1.80421979,-2.150395205,-2.466192539,-2.285888099,3.94734505,2.100943203,-9.518858356,-9.123144684,-9.033809555,-9.057015305,-10.32828936,-10.05203288,-8.619667813,-7.34346731 -2022,N130M,-0.046735915,-0.282326592,-1.508498803,-2.240817461,-2.926565916,-0.025133531,-0.056008922,-0.037462908,0.191155005,-0.196990649,-0.367662535,-1.589356532,-1.427641074,-2.061585285,-2.420049636,-2.69552931,-3.157602522,2.601656629,0.972467974,-13.26129156,-12.0830046,-12.23582504,-15.28310062,-13.05174718,-13.65278037,-10.20320526,-11.01779993 -2023,N130L,-0.061197303,-0.145357151,-1.656767283,-2.311062816,-3.026300201,-0.011388817,-0.077565649,-0.044828956,0.032792513,-0.064433443,-0.226280858,-1.58869992,-1.724834646,-2.135331344,-2.486794288,-2.58521518,-3.467385222,0.672870245,0.016609234,-13.31213448,-12.38581644,-12.38808017,-15.52882551,-12.91444947,-13.34350081,-10.20320526,-11.01779993 -2024,N130Q,0.080382455,0.067851833,-0.03985369,-1.45297514,-2.840569764,-0.093469852,-0.024992275,0.185757185,0.09773332,0.087780114,0.047923552,0.017892537,-0.097599917,-1.274069015,-1.631881265,-3.089856628,-2.5912829,0.609229399,0.715041694,-10.82362021,-10.06617358,-10.42454898,-11.36405898,-11.09258118,-11.17073836,-8.921545175,-7.475800759 -2025,N130P,-0.00103399,-0.855582924,-1.802776286,-2.130373139,-3.224951491,0.037335375,-0.072071789,0.07000381,0.108277614,-0.848693711,-0.862472136,-1.787728617,-1.817823955,-2.01820485,-2.242541428,-2.770838663,-3.679064318,3.209742597,1.256410713,-13.48429045,-12.61478319,-12.27783862,-14.80128957,-13.78832182,-13.93921903,-10.14242229,-10.76554452 -2026,N130S,0.021364942,0.074347767,0.00060289,-0.021363454,-1.617914446,-0.099201536,-0.013080459,0.055810343,-0.022724814,0.067129714,0.08156582,0.020918333,-0.019712553,0.013989796,-0.056716703,-1.725102996,-1.510725895,0.695594781,1.310974656,-7.483133296,-7.113253471,-4.955581055,-8.85895166,-8.425829193,-8.062051102,-6.931667112,-4.081639419 -2027,N130R,-0.0362617,-1.257133593,-1.883533601,-1.968055698,-3.191577633,-0.065587718,-0.060221241,-0.012302159,0.034459673,-1.325170077,-1.189097109,-1.725081808,-2.041985394,-1.947641933,-1.988469462,-2.727713993,-3.655441273,3.866025517,1.722257906,-10.32228416,-9.107186668,-11.10508169,-10.31290812,-10.64531119,-10.44093311,-8.479675993,-7.487590025 -2028,N130T,-0.058607249,0.017226658,-0.697481475,-1.777853096,-3.144842789,-0.00885697,-0.067965277,-0.049249221,0.157296738,0.043250173,-0.008796857,-0.717848879,-0.677114071,-1.637705424,-1.918000768,-2.731041937,-3.55864364,2.07927183,1.022977183,-9.676923064,-8.969382713,-7.329405746,-11.31274644,-10.03719245,-10.73588797,-8.251362366,-6.640448038 -2029,N130W,-0.024835814,-1.310343739,-1.855493663,-2.150861522,-3.060188993,-0.06368613,-0.059137923,0.009466296,0.183329668,-1.261665534,-1.359021943,-1.636945719,-2.074041606,-2.310819835,-1.990903208,-2.847853847,-3.272524138,3.042315896,0.965863429,-13.1561764,-12.37614291,-12.82886566,-13.91650491,-13.46400338,-13.19536515,-10.20320526,-11.01779993 -2030,N130V,-0.017208553,-0.513993003,-1.647175244,-2.019994083,-2.651170303,-0.019462686,-0.031363065,-0.00305404,-0.012964977,-0.526614871,-0.501371134,-1.617706361,-1.676644127,-2.078505652,-1.961482514,-2.682486453,-2.619854153,2.958213569,1.173828442,-13.47061243,-12.36999066,-13.30877235,-14.88097434,-13.15816711,-13.63515768,-10.20320526,-11.01779993 -2031,N130Y,-0.058959356,-1.426318726,-1.677800284,-1.942094189,-2.880417633,-0.001114889,-0.02817506,-0.089743651,-0.114954516,-1.527669449,-1.324968003,-1.586679672,-1.768920895,-1.927339109,-1.956849268,-2.589311857,-3.171523409,4.114951448,1.902815074,-12.5830251,-11.84163783,-12.72054424,-12.38801036,-13.37711244,-12.58782061,-9.485482959,-8.173117226 -2032,T131A,0.048297398,0.004449922,0.02299577,-0.029260658,-0.057694497,-0.012444213,0.042129751,0.054465044,-0.056604423,-0.071647707,0.080547551,-0.035675033,0.081666573,-0.065340446,0.006819131,-0.080458732,-0.034930261,1.514398944,2.4542899,-4.246565831,-6.609854141,-2.666873261,-4.618322746,-4.677796371,-2.659982636,-5.073301823,-1.70212163 -2033,T131C,0.013286749,-0.008771147,0.012372812,0.01915539,-0.280105193,0.070015408,-0.000657014,0.027230511,0.051342263,-0.026297281,0.008754987,-0.028427311,0.053172934,0.009204986,0.029105793,-0.233781008,-0.326429378,1.159418384,1.867914336,-8.927557831,-10.38276093,-8.135883308,-8.573146202,-9.710283585,-7.835715126,-7.96272109,-4.885169463 -2034,T131E,0.014478833,0.04320562,-0.68795339,-2.074980318,-2.26700351,-0.02890722,0.043174524,-0.014216859,-0.012240499,-0.039854104,0.126265343,-0.337759154,-1.038147626,-1.152091357,-2.997869279,-1.795903048,-2.738103971,3.10804231,2.267493423,-10.92003821,-11.98953738,-9.782994125,-12.53009324,-11.31500587,-8.982560417,-8.066085602,-4.236736375 -2035,T131D,-0.094024934,-0.350899547,-1.191625028,-1.880966217,-2.363424755,0.069995758,-0.051876448,-0.136173419,-0.137672152,-0.144796988,-0.557002106,-1.236823776,-1.14642628,-1.795152953,-1.966779481,-1.71880534,-3.008044169,4.089583049,2.678782411,-11.69234144,-14.42583477,-11.90158421,-14.36455279,-10.79145442,-6.978280998,-8.54861227,-5.05816539 -2036,T131G,0.047606494,0.013551701,0.012045051,0.03017478,-0.0515058,-0.024579448,0.042201062,0.053011925,0.0000409,-0.062548746,0.089652148,-0.02412637,0.048216472,0.012509791,0.047839768,-0.064465288,-0.038546311,1.461429717,2.542843565,-7.088991402,-8.60154879,-4.817755928,-8.218120277,-8.63810849,-5.169423523,-6.01476389,-3.394529534 -2037,T131F,0.001494859,0.052081815,0.04874863,-0.095103385,-1.867364177,0.060898747,0.014406205,-0.011416488,0.10455611,-0.047708494,0.151872124,-0.017418749,0.114916008,0.021557933,-0.211764702,-1.442284844,-2.292443509,0.81676416,1.333682387,-10.59671192,-13.56747997,-9.515429123,-10.23048791,-12.20748679,-7.462675827,-7.770374588,-4.868697549 -2038,T131I,0.002171054,-0.122951715,-1.20479453,-2.222924378,-2.899965958,-0.022934467,0.048435571,-0.044093464,0.02428686,-0.082489638,-0.163413792,-1.013969286,-1.395619774,-1.952979466,-2.49286929,-2.566827933,-3.233103983,2.619610036,1.224999762,-9.405303828,-10.57299089,-8.578396675,-9.376633804,-11.77050418,-6.727993591,-7.51698672,-3.431465041 -2039,T131H,0.028226936,0.02463272,0.058249781,-1.14772423,-1.881907864,0.02076724,0.058959531,-0.00250566,0.001041058,0.011361658,0.037903782,0.022919771,0.093579791,-1.005900082,-1.289548378,-2.306129426,-1.457686302,1.980144393,1.328163266,-12.43942887,-16.253795,-10.80072688,-12.38720581,-12.06989527,-10.68552142,-9.067932449,-5.568424604 -2040,T131K,-0.058575127,-0.028344682,-1.106862664,-1.834230874,-2.769964672,0.04038543,-0.064238544,-0.05291171,-0.047411891,-0.082164119,0.025474756,-0.92262283,-1.291102497,-1.815222936,-1.853238812,-2.265214601,-3.274714742,3.302068293,1.941865957,-13.56810852,-14.7295565,-14.68345431,-13.33579398,-13.23829883,-11.85343899,-10.32832796,-7.642594571 -2041,T131M,0.021392737,0.066812967,0.063199091,-0.015479573,-2.285306579,0.001275874,0.053564499,-0.010779025,0.012610228,0.031158667,0.102467267,0.049264407,0.077133774,0.073005109,-0.103964255,-1.737855253,-2.832757904,0.619073018,1.306643808,-9.861472601,-12.29019492,-8.348089005,-9.240649178,-11.69247783,-7.73595208,-8.220714059,-4.712211831 -2042,T131L,0.022006502,0.034902455,0.035972631,0.04639541,-1.456442477,0.042640594,0.018568335,0.025444668,-0.02323047,-0.033005957,0.102810866,-0.007412929,0.079358191,0.06070085,0.03208997,-1.392526659,-1.520358294,0.650505043,1.32569687,-8.174373665,-10.80712489,-6.380018967,-6.944152206,-10.76862739,-5.971944878,-6.86075613,-2.594168944 -2043,T131N,0.052592318,0.081785523,0.06686613,-1.219654723,-2.095417997,0.01203924,0.049016871,0.056167765,-0.02008759,-0.061074337,0.224645383,-0.051201871,0.18493413,-1.206410527,-1.232898919,-1.938948782,-2.251887212,2.661051326,1.843559412,-10.06126338,-13.27005539,-9.455758163,-12.5036532,-8.562573181,-6.514276962,-8.906852995,-2.284009593 -2044,T131Q,0.052493263,0.065880434,-0.203876569,-1.434802519,-3.027916002,-0.021407805,0.093950274,0.011036252,0.00503871,0.00893029,0.122830577,-0.140835973,-0.266917165,-1.320855732,-1.548749305,-2.853034153,-3.20279785,1.076757593,0.761986683,-12.04628926,-13.36329772,-10.75826996,-13.00881847,-12.42807006,-10.67299008,-9.025999968,-5.538630083 -2045,T131P,-0.002501147,0.017751106,-0.067160285,-1.437859926,-2.281962266,0.030246559,0.025453949,-0.030456243,-0.032146624,-0.02667684,0.062179051,-0.025140923,-0.109179646,-1.320431939,-1.555287913,-2.31841307,-2.245511462,0.434296412,0.701866598,-7.53475773,-9.945623276,-5.960029106,-7.604709053,-9.026103188,-5.137324028,-7.20415787,-3.51864778 -2046,T131S,0.046852555,0.032947322,0.074513191,0.031751946,-0.001675894,-0.038013249,0.046399272,0.047305837,0.028249964,-0.03163583,0.097530474,0.043441286,0.105585096,0.004992831,0.05851106,0.000939062,-0.004290849,1.248566977,2.72936441,-3.821205298,-4.472364311,-3.18822287,-4.050491608,-4.644079247,-2.750868454,-4.463425473,-2.522269712 -2047,T131R,0.050172973,0.039187439,-1.13788643,-1.812974307,-2.156756897,0.005204788,0.067078301,0.033267644,-0.038858987,-0.02052667,0.098901548,-0.982260057,-1.293512803,-1.559894389,-2.066054225,-2.124524834,-2.188988959,3.628021564,2.358921315,-12.75870828,-14.96183696,-10.28337519,-13.48510148,-12.98279372,-12.08043405,-9.342256839,-5.916655881 -2048,T131W,0.021055777,-0.002815329,-0.085255308,-1.424399157,-2.299041508,0.01387109,0.040213791,0.001897762,-0.003721882,-0.061463957,0.055833299,-0.055846379,-0.114664237,-1.303434223,-1.545364091,-2.038326383,-2.559756632,2.581354826,1.712923916,-12.75646131,-15.22410963,-11.18275576,-12.99697552,-13.64308494,-10.73538071,-9.800797657,-6.314157085 -2049,T131V,0.007907616,0.038888167,0.082390051,0.069681459,-1.578518336,0.007673937,0.016066771,-0.00025154,-0.033384935,0.01560534,0.062170994,0.059167444,0.105612658,0.123954756,0.015408161,-1.529645828,-1.627390844,0.130428738,1.299862708,-6.790883974,-8.165201324,-5.51369799,-6.767639915,-9.373176628,-4.13470401,-5.90168151,-2.674712582 -2050,T131Y,0.118888056,0.057136108,0.052911576,-0.695978974,-1.847027324,-0.005336982,0.122903503,0.114872608,-0.00513964,-0.073755368,0.188027584,-0.065046197,0.170869349,-0.346137637,-1.04582031,-1.808615013,-1.885439634,1.520045735,1.388395057,-11.48385724,-15.21080721,-10.45551006,-11.23754785,-11.73262743,-8.782793678,-8.30285788,-4.266752662 -2051,A132C,-0.006064091,0.029966263,-0.501014401,-1.437874555,-2.939642149,0.018458061,0.025583765,-0.037711947,0.012604995,0.097407365,-0.03747484,-0.237032501,-0.764996301,-1.41100089,-1.464748219,-2.736940785,-3.142343512,1.327313557,0.803476356,-5.853107501,-6.582799026,-3.789328651,-5.651686348,-8.773572342,-4.468151138,-5.49571702,-4.022096908 -2052,A132E,0.114228499,-1.43646584,-1.591899839,-1.785240095,-2.062191363,0.03875047,0.147340431,0.081116567,-0.00365282,-1.673624145,-1.199307535,-1.708610403,-1.475189275,-1.946819688,-1.623660501,-2.545760855,-1.578621871,-0.04555221,-1.003656415,-10.51240111,-10.21643024,-10.50315656,-10.11584777,-11.10218322,-10.62438775,-9.72973559,-10.89818902 -2053,A132D,0.123345169,-1.424809317,-1.939286464,-2.453659296,-2.770201187,0.03346145,0.185361289,0.061329048,-0.077310373,-1.607088424,-1.24253021,-1.943104678,-1.93546825,-2.005222705,-2.902095887,-2.604163871,-2.936238503,-0.037436219,-1.024809728,-10.84490336,-10.55430067,-10.95464105,-10.59341626,-11.3753049,-10.74685392,-9.72973559,-10.89818902 -2054,A132G,0.012875998,0.032919828,0.029576208,-0.951044932,-1.824772543,0.029134626,0.025100992,0.000651003,-0.001720807,0.079466798,-0.013627142,0.017328294,0.041824122,-0.477978561,-1.424111302,-2.046956504,-1.602588581,1.65032148,1.369195617,-4.981527443,-3.399084785,-6.03902446,-4.401973328,-4.556239304,-6.511315338,-4.812985281,-2.992713268 -2055,A132F,0.032811053,-1.449931937,-2.065231766,-2.556725852,-2.873267744,-0.043875388,0.069115344,-0.003493238,-0.025723339,-1.530773819,-1.369090055,-1.866790073,-2.263673459,-2.104999358,-3.008452346,-2.703940525,-3.042594962,0.10320787,-0.95203174,-10.66905999,-11.04531861,-9.018539787,-10.73556838,-12.81246387,-9.733409279,-8.428305965,-8.117334739 -2056,A132I,0.009760616,-1.70974813,-2.475562956,-2.42746642,-2.806477679,0.01298041,-0.032247231,0.051768462,-0.085366657,-1.658560398,-1.760935861,-2.295606648,-2.655519264,-2.232785938,-2.622146901,-2.655635845,-2.957319513,-0.145854076,-1.065521983,-10.03374351,-10.26466418,-9.488431534,-9.169355644,-11.26150651,-9.984759659,-8.048737693,-6.609464196 -2057,A132H,0.116313931,-1.527950804,-2.021731608,-2.274665067,-2.352646332,0.111492013,0.117537473,0.115090388,-0.068841968,-1.26062039,-1.795281218,-1.897666639,-2.145796576,-2.135875925,-2.413454209,-2.257695837,-2.447596826,3.835529539,1.616839589,-10.71533692,-11.01394444,-9.824030365,-10.2113696,-11.74507465,-10.78226556,-9.72973559,-10.89818902 -2058,A132K,0.040213241,-1.671123709,-1.863874517,-2.744444229,-2.822425493,0.11316524,0.06835418,0.012072301,-0.096010872,-1.731307534,-1.610939883,-2.067323788,-1.660425246,-2.606563069,-2.882325389,-2.728382981,-2.916468005,-0.214287717,-1.069204396,-11.04650336,-11.04853158,-10.58577379,-10.45940125,-11.89576771,-11.24304246,-9.72973559,-10.89818902 -2059,A132M,0.090223404,-1.296283006,-2.079955608,-2.293298444,-2.760355333,0.072039739,0.116418157,0.06402865,-0.077310373,-1.37011953,-1.222446481,-2.308195775,-1.851715441,-1.76825381,-2.818343078,-2.668224972,-2.852485694,0.378560797,-0.839550095,-11.13301672,-11.54976551,-10.7554671,-10.54537672,-12.78661772,-10.02785655,-9.248606446,-8.777925005 -2060,A132L,0.037136439,-1.755431482,-2.136470769,-2.222177353,-3.316870495,0.031193143,0.039675974,0.034596904,-0.114898058,-1.547910574,-1.96295239,-2.114375749,-2.158565789,-2.09731253,-2.347042175,-3.173374951,-3.460366038,0.359371583,-0.956849455,-9.922089066,-10.14306073,-8.818730827,-9.282764191,-11.86145026,-9.504439316,-7.883132478,-5.875809568 -2061,A132N,-0.035823613,-1.5423479,-2.124174334,-2.615668421,-2.693649685,0.011981297,-0.042590637,-0.029056589,-0.025303934,-1.629508601,-1.455187199,-1.965524855,-2.282823813,-2.203734141,-3.0276027,-2.626584048,-2.760715321,-0.288281379,-1.029582573,-11.12883051,-11.12199509,-10.98154572,-10.46085942,-11.81339555,-11.26635675,-9.72973559,-10.89818902 -2062,A132Q,0.223275258,-1.464977241,-1.444743683,-1.848192141,-2.31524903,-0.007387058,0.236992088,0.209558427,-0.024547981,-1.445144816,-1.484809666,-1.480131074,-1.409356292,-2.195461615,-1.500922666,-2.317281527,-2.313216533,3.660027638,1.539543387,-10.88706402,-10.73500231,-10.37638845,-10.32904043,-11.78034626,-11.21454266,-9.72973559,-10.89818902 -2063,A132P,0.054740123,-1.359358557,-1.978764977,-2.232701428,-2.31679992,0.06392502,0.040229705,0.069250541,-0.094580819,-1.304114373,-1.414602741,-2.127471047,-1.830058907,-2.131597127,-2.333805729,-2.332598285,-2.301001555,0.63560276,-0.765154568,-9.453728931,-8.831089066,-9.837172417,-9.266142143,-9.79164328,-9.542597748,-8.347959236,-7.434468637 -2064,A132S,0.048387742,0.031828906,0.014568271,-0.006924017,-1.153553251,0.000141085,0.062201562,0.034573921,-0.003773878,0.032633963,0.031023849,0.009955158,0.019181384,0.01038225,-0.024230284,-0.830400434,-1.476706067,0.57354371,1.350739897,-5.656036943,-5.217252464,-5.80262352,-5.26595855,-6.557216553,-5.437133629,-6.035190669,-4.007072365 -2065,A132R,-0.031128682,-1.678372908,-2.015521486,-2.873212453,-3.12458746,0.066831497,-0.034769594,-0.02748777,-0.070073994,-1.715699951,-1.641045865,-1.817632999,-2.213409973,-2.612144786,-3.13428012,-2.955813447,-3.293361473,-0.020652138,-1.05255572,-10.77764605,-10.59519766,-10.41551293,-10.39286393,-11.30013215,-11.1845236,-9.478356107,-9.568577795 -2066,A132T,-0.005427035,-0.006983294,-1.215919415,-1.684534757,-2.174470391,0.019224322,0.017731886,-0.028585956,-0.035831681,0.118813778,-0.132780365,-1.22438106,-1.20745777,-1.580689658,-1.788379855,-2.128478302,-2.220462479,3.805997275,2.457253178,-6.68337422,-6.465436813,-6.510020493,-6.187431564,-7.202506813,-7.051475418,-6.301641336,-4.139465701 -2067,A132W,0.012252581,-1.579268667,-1.958212428,-3.022770532,-2.862191169,0.042107536,0.038675114,-0.014169952,-0.060030026,-1.475917158,-1.682620175,-1.774144852,-2.142280003,-2.790505387,-3.255035676,-2.435204045,-3.289178292,0.531592282,-1.081598591,-11.44642563,-11.57371535,-10.68510567,-11.15671055,-12.74865271,-11.06794385,-9.72973559,-10.89818902 -2068,A132V,0.014852203,-0.934913715,-1.553099828,-1.875184636,-1.95815801,0.036240483,0.024177119,0.005527287,0.01766514,-0.770534158,-1.099293272,-1.764127731,-1.342071924,-1.964548455,-1.785820816,-2.086368367,-1.829947653,4.363113437,2.470141578,-8.552688213,-8.871125443,-8.242530334,-7.75441626,-9.585092171,-8.310276855,-7.929021318,-6.605900367 -2069,A132Y,0.040473425,-1.508546489,-2.377388556,-2.780837013,-2.858818277,-0.005584562,0.079588475,0.001358374,-0.014423556,-1.528482022,-1.488610955,-2.040589535,-2.714187577,-2.579828816,-2.98184521,-2.701648728,-3.015987826,-0.2123052,-0.983991156,-11.5382529,-11.63020685,-10.21801668,-11.43909747,-13.44771854,-10.95622496,-9.72973559,-10.89818902 -2070,A133C,-0.00774145,0.001291328,0.037568662,-0.003170465,-1.849881352,0.096780884,-0.007817289,-0.00766561,-0.01070332,-0.034425536,0.037008192,0.035726364,0.039410959,0.0536446,-0.05998553,-1.702430536,-1.997332167,0.578072086,1.308581815,-9.389295607,-10.07753066,-8.681223152,-9.953741989,-8.865463959,-9.368518272,-6.656134571,-1.646372244 -2071,A133E,-0.052919691,-1.26141188,-2.156214639,-2.164244365,-2.123472185,0.09342379,-0.057826017,-0.048013364,-0.055258883,-1.284628786,-1.238194974,-2.046460392,-2.265968886,-1.860251999,-2.46823673,-2.261738547,-1.985205822,0.710260734,-0.731128344,-10.38900965,-10.70936898,-9.677686874,-11.33146502,-10.56433263,-9.66219474,-7.004870955,-5.546053054 -2072,A133D,-0.060583051,-1.197046488,-1.793192469,-1.641223277,-1.559206196,0.086565835,-0.049196497,-0.071969605,-0.029375918,-1.125666853,-1.268426123,-1.66564971,-1.920735228,-1.490436701,-1.792009853,-1.801746619,-1.316665773,4.555122369,2.718828357,-9.25564059,-11.70155454,-8.116262825,-9.58336055,-9.877907928,-6.999117104,-6.404737485,-4.729045598 -2073,A133G,-0.020973722,0.019722894,0.009274628,0.022143252,-0.05375177,0.01095523,-0.044556731,0.002609288,-0.043059914,-0.05470645,0.094152237,-0.000827706,0.019376962,0.003949906,0.040336597,-0.068984932,-0.038518607,1.38979435,2.429750622,-2.114148592,-2.90629068,-0.978243462,-2.035452698,-2.836130562,-1.814625557,-2.057832576,-1.22210873 -2074,A133F,-0.063003197,-0.161123851,-1.566228016,-2.287242107,-2.774922353,0.081603475,-0.026656091,-0.099350303,-0.087204649,-0.017872849,-0.304374853,-1.273272562,-1.85918347,-1.910972909,-2.663511305,-2.789580712,-2.760263994,2.527726898,1.081890835,-13.2825995,-13.01485751,-12.30837585,-15.19420873,-15.20173439,-10.69382101,-7.084619459,-4.132919461 -2075,A133I,-0.177098339,-1.082032108,-1.902831071,-2.362405789,-2.810495412,0.016525928,-0.139012072,-0.215184605,-0.147746536,-0.762590155,-1.40147406,-1.737029855,-2.068632286,-1.754941444,-2.969870134,-2.554368001,-3.066622823,4.03891515,2.154251558,-8.751213298,-7.486889832,-8.086217293,-9.537004341,-10.36031095,-8.285644073,-5.97459938,-4.9894596 -2076,A133H,-0.043598824,-0.828241888,-2.190497255,-2.572620994,-2.631634991,0.028374381,-0.04745368,-0.039743968,0.003959035,-0.705576717,-0.950907059,-2.166378328,-2.214616182,-1.883259921,-3.261982066,-2.205565224,-3.057704758,0.644202402,-0.508058127,-12.08671349,-12.97476728,-11.02879521,-12.91909661,-12.4042501,-11.10665824,-6.687620064,-5.057104272 -2077,A133K,-0.017349745,-1.32063772,-2.242671018,-2.46368511,-2.261259734,0.204754119,0.072780021,-0.107479511,-0.058972827,-1.204733827,-1.436541613,-2.010031127,-2.475310909,-2.249791466,-2.677578753,-2.350248018,-2.17227145,0.545300492,-0.715764041,-13.19439943,-14.33375819,-11.14777094,-13.90210912,-13.46599479,-13.12236411,-9.504542946,-9.511394586 -2078,A133M,0.028706852,-1.079755671,-2.400966287,-2.621980379,-2.570070001,0.040153741,0.014876974,0.04253673,-0.158257748,-1.03953191,-1.119979431,-2.203851153,-2.598081421,-2.443611492,-2.800349265,-2.544068044,-2.596071958,1.042139125,-0.567285919,-9.771020815,-10.40731659,-7.970757126,-11.66663051,-11.33992259,-7.470477257,-5.961816046,-3.288642806 -2079,A133L,-0.023771839,-1.438953689,-1.914494184,-2.408779607,-3.356869229,-0.001307246,-0.040304201,-0.007239476,-0.075257224,-1.53840066,-1.339506718,-1.885544545,-1.943443822,-2.329424866,-2.488134347,-2.952760164,-3.760978294,0.259806378,-0.936989631,-10.74899775,-9.383950073,-9.574002411,-12.77702496,-12.16264791,-9.847363396,-6.396691796,-4.166792226 -2080,A133N,-0.033292747,-0.112756883,-1.638780383,-2.58337349,-2.531463113,0.070961269,-0.053428335,-0.013157159,-0.064517781,-0.158221697,-0.067292068,-1.32254094,-1.955019825,-2.407399319,-2.75934766,-2.507855872,-2.555070353,1.070058006,0.116851439,-9.605253931,-12.00489783,-7.957694389,-10.49814243,-8.553965309,-9.011569695,-6.204463429,-2.829194632 -2081,A133Q,-0.023546229,-1.310598168,-2.390766448,-2.549311171,-2.948945787,0.057132711,-0.002123469,-0.044968988,-0.146579722,-1.357595245,-1.263601091,-1.919854497,-2.861678398,-2.034676099,-3.063946242,-2.737192643,-3.16069893,3.595524223,1.277128463,-10.7025718,-11.49320576,-9.437451096,-11.95676651,-11.02177103,-9.603664581,-6.449225778,-5.065392547 -2082,A133P,-0.040955646,0.012284614,-0.882498583,-1.925318455,-2.451581678,0.056875402,-0.048502956,-0.033408335,-0.024980273,-0.080533337,0.105102564,-0.494208593,-1.270788572,-1.768420162,-2.082216748,-2.481155871,-2.422007485,1.840730024,0.87914301,-11.33930482,-12.11989972,-10.01776789,-11.81966429,-12.75390804,-9.985284164,-8.210376834,-6.551920834 -2083,A133S,-0.012720949,-0.026892709,0.001395003,0.0000339,-0.157756724,0.010813072,-0.04888161,0.023439713,-0.007852237,-0.092183108,0.038397691,0.001109568,0.001680438,-0.036577086,0.03664495,-0.162017303,-0.153496145,1.349787602,2.118171785,-5.868307744,-7.650990753,-5.309726974,-4.762800125,-6.779021667,-4.838999199,-5.161482371,-1.780772203 -2084,A133R,-0.057304828,-1.494103276,-2.121975064,-2.504016721,-3.152806614,0.098175297,-0.052174997,-0.062434658,-0.050819401,-1.587892976,-1.400313576,-1.902367744,-2.341582383,-2.181636624,-2.826396817,-2.905342467,-3.400270761,0.074557381,-0.986654992,-12.96936906,-13.85266205,-12.13774004,-14.21762111,-12.97143096,-11.66739115,-8.598798594,-7.209853283 -2085,A133T,-0.052233511,-0.029663601,-0.0336638,-0.051248148,-0.124961472,0.240186931,-0.077983089,-0.026483933,-0.02073436,-0.087887381,0.02856018,-0.03839383,-0.02893377,-0.034589767,-0.067906528,-0.132528663,-0.11739428,1.38511591,2.253642628,-5.790642128,-6.242858147,-4.903600319,-5.131874931,-7.331711067,-5.343166176,-4.099609931,-0.277679915 -2086,A133W,-0.039195892,-1.686324619,-2.166296844,-2.750810299,-2.815941524,0.060651124,-0.048767156,-0.029624628,-0.204396868,-1.812635425,-1.560013813,-1.823987208,-2.508606479,-2.489716279,-3.011904318,-3.067294086,-2.564588962,0.200752119,-1.143334729,-14.05845078,-14.3170363,-12.42222981,-15.7039803,-15.26654169,-12.58246579,-8.158189584,-6.551920561 -2087,A133V,-0.06317093,0.0000908,-0.718635949,-1.815755198,-2.07968605,0.035907141,-0.069466787,-0.056875072,-0.021419075,-0.038935518,0.039117116,-0.362355132,-1.074916765,-1.51162056,-2.119889836,-2.059235143,-2.100136956,3.163755076,2.107755516,-6.042386853,-4.177285721,-6.507542961,-6.505611946,-7.407618523,-5.613875114,-4.373040704,-3.527189906 -2088,A133Y,-0.02818377,-1.072351789,-1.965880954,-2.451031934,-3.001181548,0.023059045,-0.015989004,-0.040378536,-0.066344536,-1.134889053,-1.009814525,-2.032940406,-1.898821501,-2.448792004,-2.453271863,-2.850278553,-3.152084542,0.359396107,-0.662271502,-14.9056176,-14.50277558,-14.69903336,-16.30012209,-15.38673055,-13.63942642,-7.312161304,-5.653100571 -2089,N134A,-0.031905678,-0.052893833,-0.050714032,-2.100340961,-2.730906615,0.036228598,-0.011659487,-0.052151868,-0.008751383,-0.012415235,-0.09337243,-0.022693356,-0.078734707,-1.835683301,-2.36499862,-2.747694683,-2.714118547,0.709957921,0.676320108,-11.05552694,-10.63572585,-12.29716949,-10.86220663,-11.15836023,-10.32417251,-7.045983366,-5.832300094 -2090,N134C,-0.01571925,-0.045847611,-0.013444764,-1.331412761,-3.421395372,0.057415135,-0.039915606,0.008477106,-0.029403756,-0.032370358,-0.059324863,-0.05451088,0.027621352,-1.274212471,-1.38861305,-3.204973289,-3.637817454,0.823992916,0.735454744,-12.30950106,-11.46564835,-12.57027802,-12.25768144,-13.5550625,-11.69883501,-8.083416532,-6.714562242 -2091,N134E,-0.078295274,-0.053043466,-1.654282741,-2.913611882,-2.946909354,0.082622979,-0.044107681,-0.112482866,0.00820283,0.041841473,-0.147928405,-1.459545705,-1.849019776,-2.230562745,-3.596661018,-2.456193251,-3.437625456,0.94902859,0.070063754,-10.9101593,-10.27388471,-11.96832476,-9.868750977,-11.75392719,-10.68590885,-6.393825785,-4.749996065 -2092,N134D,-0.035669378,-0.051015135,-0.00905534,-0.255137305,-2.099289227,0.072136682,0.001332419,-0.072671174,-0.086119805,-0.01091849,-0.09111178,-0.023083953,0.004973273,-0.033893987,-0.476380623,-1.831154528,-2.367423925,0.786216963,1.308667843,-7.046112146,-6.377023834,-6.372872887,-6.443305305,-7.84788195,-8.189476753,-4.720078186,-0.914599567 -2093,N134G,-0.042696061,-0.009795514,-0.145007691,-2.095297776,-2.942513058,0.06241614,-0.017741328,-0.067650793,-0.008849751,0.025510584,-0.045101611,-0.062782257,-0.227233124,-1.920514221,-2.270081331,-2.790067165,-3.09495895,0.741696408,0.667412464,-10.42146123,-9.592662025,-10.91589333,-10.94190007,-10.73856033,-9.918290398,-7.007411547,-5.203899748 -2094,N134F,0.010498702,0.007487915,-0.344239229,-2.15392903,-3.187226502,0.007743906,0.032978118,-0.011980714,0.006107,-0.010664201,0.025640031,-0.234071887,-0.454406571,-1.886780769,-2.42107729,-2.811381279,-3.563071724,1.213764948,0.701710031,-12.88434884,-11.06513589,-13.25898917,-11.94002518,-14.99677922,-13.16081474,-7.547883882,-5.87411083 -2095,N134I,-0.046673061,-0.009829494,-0.131542506,-2.395542408,-2.830199601,0.065328108,-0.01040813,-0.082937991,-0.019010722,-0.001396515,-0.018262473,-0.068053453,-0.195031559,-1.673173149,-3.117911666,-2.099463105,-3.560936096,0.748306136,0.693151956,-10.08582968,-8.239144936,-11.11518974,-9.893124352,-12.4260285,-8.755660858,-6.544382465,-4.675488579 -2096,N134H,-0.029996631,-0.004613213,-0.0000295,-1.912451648,-2.534620405,0.042258175,-0.007796746,-0.052196516,0.013857851,0.016669241,-0.025895666,-0.004333887,0.004274863,-1.821982023,-2.002921273,-2.131933414,-2.937307396,0.668888598,0.675567629,-11.07472223,-10.3318203,-11.68149506,-11.27882735,-12.45844143,-9.623027,-7.147283713,-5.096033422 -2097,N134K,-0.033739776,0.01467132,-0.013498547,-2.214526153,-3.1263046,0.142865251,-0.010837392,-0.056642159,0.015363206,0.00437672,0.024965919,-0.062289496,0.035292402,-1.659630575,-2.76942173,-2.739133045,-3.513476155,0.812285027,0.698007114,-10.26030675,-9.642944069,-9.558576263,-10.47564099,-11.91747797,-9.706894447,-7.041619507,-5.491060003 -2098,N134M,-0.049266104,-0.05664246,-0.130332789,-2.387290182,-2.975159889,0.051295742,-0.021970349,-0.076561858,0.022073333,-0.064668529,-0.04861639,-0.079771788,-0.18089379,-2.089349574,-2.685230789,-2.344943303,-3.605376474,0.689315232,0.64309882,-12.33233237,-10.55327546,-12.39575195,-12.6530474,-14.26567594,-11.79391107,-7.948603565,-6.714562211 -2099,N134L,-0.029542872,-0.018657669,-1.534011065,-2.022538301,-2.878500113,0.055225166,0.00324346,-0.062329204,-0.043735358,0.002171321,-0.039486658,-1.49123858,-1.576783549,-2.096480629,-1.948595972,-3.146019875,-2.610980351,0.23709827,0.01807044,-10.79479305,-9.172898636,-10.38800302,-11.51635293,-13.29052838,-9.606182297,-6.015359236,-3.270115207 -2100,N134Q,-0.062254286,-0.022490201,-0.007066445,-1.692547362,-3.055870804,0.10440362,-0.046463643,-0.078044929,0.002472715,0.033018868,-0.077999269,0.023879714,-0.038012603,-1.494933685,-1.890161039,-2.477526142,-3.634215465,0.644768291,0.702607311,-11.72171691,-11.41799112,-11.49758872,-11.50646503,-12.92059914,-11.26594056,-7.202670834,-5.874110754 -2101,N134P,-0.044540223,-1.523915926,-1.951090146,-2.612290159,-3.4871755,0.042372859,-0.040107091,-0.048973354,-0.045100921,-1.512840084,-1.534991767,-1.757867527,-2.144312764,-2.019007189,-3.205573129,-2.927813432,-4.046537568,3.505642387,1.211322266,-14.45038301,-13.34624961,-15.19516088,-14.25503292,-15.90435201,-13.55111964,-9.637723922,-10.19675467 -2102,N134S,-0.047201715,-0.016152634,-0.036010367,-1.87868483,-2.914040585,0.085059596,-0.021479542,-0.072923888,-0.012722913,-0.015672712,-0.016632555,-0.065417101,-0.006603632,-1.489961703,-2.267407956,-2.233042202,-3.595038967,0.901122658,0.719779364,-10.732342,-9.959911346,-11.69039423,-11.01382729,-11.86434983,-9.13322728,-8.730166328,-7.771299106 -2103,N134R,-0.048921831,0.003094664,-0.01086617,-2.122802422,-3.074171492,0.090237751,-0.039365822,-0.058477839,-0.010479412,0.030346911,-0.024157584,-0.023213246,0.001480907,-1.950470648,-2.295134195,-2.45594185,-3.692401134,0.56372064,0.661227564,-12.85331412,-11.57918983,-14.37192673,-13.03938541,-13.69802308,-11.57804555,-6.98778989,-5.326581798 -2104,N134T,-0.022748057,-0.006699095,-0.009502881,-1.240925999,-2.597705253,0.054396413,-0.011207449,-0.034288665,-0.028674185,0.007908243,-0.021306433,-0.027024659,0.008018897,-1.003159122,-1.478692875,-2.222540679,-2.972869827,2.050725303,1.39093148,-8.73578004,-7.600750511,-9.12375045,-8.796739319,-10.2345674,-7.923092522,-7.088532999,-6.312017684 -2105,N134W,-0.044790109,-0.013371137,-1.453378166,-2.308560728,-3.258416571,0.047954748,-0.022183973,-0.067396244,0.004268285,-0.016559696,-0.010182578,-1.389663843,-1.517092489,-2.105715391,-2.511406064,-2.749489291,-3.767343851,2.358808048,0.855051139,-14.8527196,-13.25204587,-15.27805738,-14.63193145,-16.7749931,-14.32657022,-9.637723922,-10.19675466 -2106,N134V,-0.014140305,0.015117081,-0.009214773,-1.76977729,-2.740153276,0.065345853,-0.002966844,-0.025313766,-0.004280686,0.023714028,0.006520134,-0.012592373,-0.005837173,-1.657660983,-1.881893597,-2.984318067,-2.495988485,0.64031039,0.688608157,-10.48935466,-8.875279915,-12.12948248,-10.45970982,-11.90717769,-9.07512339,-6.721214749,-5.540741262 -2107,N134Y,-0.036495178,-0.015402827,-0.106558883,-1.959095608,-2.998510307,0.043191537,-0.018225627,-0.054764729,0.009372842,0.021653278,-0.052458932,0.029380627,-0.242498392,-1.831993962,-2.086197253,-2.388617686,-3.608402928,0.565377374,0.674038577,-13.30681882,-12.53292814,-13.82758156,-12.06288181,-14.61598795,-13.49471465,-7.640701506,-4.912788031 -2108,L135A,-0.02112953,0.010085161,0.005087024,0.024460949,-1.73120652,0.032501255,-0.009176701,-0.033082358,-0.04772345,-0.011639959,0.031810281,0.0109659,-0.000791853,0.043982252,0.004939646,-1.587102507,-1.875310533,0.748525912,1.319716531,-7.213489928,-7.591431007,-9.282946922,-5.359962395,-7.711955338,-6.121153976,-5.936601506,-1.754946522 -2109,L135C,-0.068192055,-0.049227127,-0.023001084,-0.245550479,-1.94117432,0.100961328,-0.075620361,-0.060763749,0.035757594,-0.070038136,-0.028416118,-0.03842676,-0.007575408,-0.079049642,-0.412051316,-1.742133104,-2.140215535,0.972925785,1.323018354,-10.31277899,-10.60326263,-11.30852621,-9.685007828,-9.835293816,-10.13180445,-8.313445902,-6.262391854 -2110,L135E,0.007769139,0.029143981,0.009569027,-0.172229151,-1.681275963,0.015336599,0.001090997,0.014447281,-0.091666698,0.030596815,0.027691146,0.036932626,-0.017794573,0.059269578,-0.403727879,-1.696077904,-1.666474021,0.496019817,1.304143634,-9.48113891,-7.940165825,-11.96383719,-7.78771685,-9.823459297,-9.890515388,-6.647918695,-4.268362122 -2111,L135D,-0.060098902,-0.872984644,-1.800587346,-2.288358611,-2.91674579,0.004086522,-0.074740738,-0.045457066,0.002506684,-0.820424178,-0.925545109,-1.695322448,-1.905852243,-2.166151115,-2.410566107,-2.732851302,-3.100640277,3.013880227,1.092637207,-13.7055961,-12.7784179,-16.37372536,-12.18777766,-14.11613171,-13.07192788,-9.984269775,-9.572265932 -2112,L135G,0.013196296,0.01755985,-0.823760714,-1.738984132,-2.374463158,0.062706009,0.039844467,-0.013451876,-0.031677281,-0.020063442,0.055183142,-0.617837862,-1.029683566,-1.503191226,-1.974777038,-2.61982839,-2.129097925,2.085673766,1.086844791,-11.02349439,-10.8954828,-13.19403145,-8.855890938,-11.35084586,-10.82122091,-7.226935132,-4.897045662 -2113,L135F,-0.014543203,0.011614278,0.012121934,-0.008153599,-1.195243408,0.037900525,0.011665464,-0.04075187,0.068940289,-0.032231694,0.055460249,-0.014307465,0.038551333,0.026693945,-0.043001142,-1.417740095,-0.97274672,0.675350322,1.323967201,-4.925340907,-4.813751976,-4.920964729,-5.727266991,-4.676099884,-4.488620956,-4.947799439,-3.626605222 -2114,L135I,0.082884663,0.01490221,0.041074388,0.024461123,0.015083205,-0.031827975,0.118980292,0.046789034,0.034212518,-0.029245282,0.059049702,-0.00661439,0.088763165,-0.00057061,0.049492855,-0.04751424,0.077680649,1.493007229,2.630361326,-4.182949367,-5.975792732,-4.25051638,-3.047071709,-4.657408043,-2.98395797,-4.356210632,-0.994550914 -2115,L135H,-0.053313506,-0.024937073,-0.012673909,-1.172863508,-1.802150135,0.037858204,-0.0422775,-0.064349511,-0.026613831,-0.039582591,-0.010291554,-0.010762827,-0.014584991,-0.994338654,-1.351388362,-2.059094002,-1.545206267,2.188042586,1.507923098,-10.24109932,-9.810795784,-11.23078505,-9.030299919,-8.921526611,-12.21208923,-7.03763026,-5.148851805 -2116,L135K,-0.012480836,0.003177875,-0.030873738,-0.427970579,-1.541480467,0.052686377,0.028258301,-0.053219973,-0.017927976,-0.009625544,0.015981293,-0.007172176,-0.054575299,-0.126402661,-0.729538497,-1.623053671,-1.459907262,1.074426554,1.344712077,-7.985608768,-9.036825653,-10.20333436,-5.804211922,-7.568170265,-7.31550164,-5.156806906,-2.566029227 -2117,L135M,-0.0324586,-0.025005153,0.032575086,-0.006326065,-0.163311658,0.020427028,-0.030792832,-0.034124367,0.004974043,0.024990601,-0.075000906,0.064383968,0.000766204,0.011470156,-0.024122285,-0.160308867,-0.166314449,1.41972547,2.254221664,-5.157165701,-5.349719574,-6.529141815,-4.862355331,-5.655430313,-3.389181473,-5.437422234,-1.398132904 -2118,L135N,0.006785134,-0.009171788,0.001135201,-1.473667881,-2.400954055,0.043084177,0.020420873,-0.006850605,-0.00965376,-0.028013031,0.009669455,0.011812269,-0.009541867,-1.303158894,-1.644176868,-2.381742442,-2.420165667,0.55444544,0.709231611,-11.25833726,-11.30514161,-12.13519597,-10.36597773,-11.39248516,-11.09288583,-8.109246784,-6.111214093 -2119,L135Q,-0.001100287,0.036382714,0.034291793,0.025451976,-1.193573049,0.042278836,0.033919461,-0.036120035,0.048353815,0.040733639,0.032031789,0.054439743,0.014143842,0.055366995,-0.004463044,-1.15516019,-1.231985908,0.688308438,1.340989175,-8.331376596,-5.718701988,-11.8915761,-6.718123756,-7.140618233,-10.1878629,-6.146894545,-3.466515381 -2120,L135P,-0.019019823,-1.496527164,-2.052370623,-2.363919347,-2.853055352,0.025867572,-0.009614815,-0.02842483,-0.048074806,-1.466004289,-1.527050039,-1.964371802,-2.140369443,-2.29438497,-2.433453723,-2.594817267,-3.111293436,0.009614745,-0.934118226,-12.67727379,-12.57299569,-14.63686118,-11.46850156,-12.5871069,-12.12090364,-9.984269775,-9.572265932 -2121,L135S,-0.003435025,-0.001286947,0.020849316,-0.901277792,-1.879872593,0.016619586,0.041274773,-0.048144822,-0.047999663,-0.015466681,0.012892787,-0.002499217,0.044197849,-0.677903818,-1.124651765,-2.089702045,-1.67004314,1.848513159,1.391908521,-8.43832287,-9.450732719,-9.785154381,-7.220001167,-8.067446167,-7.668279915,-6.166430375,-4.659426326 -2122,L135R,-0.030322266,-0.019481681,0.007083736,-1.212068172,-1.891850718,0.044034616,-0.026117932,-0.034526599,-0.057566589,-0.010008397,-0.028954964,0.006254382,0.007913089,-0.841499551,-1.582636792,-2.133021546,-1.650679889,1.848576741,1.352505485,-9.231775661,-7.603329933,-10.93156673,-7.558507744,-8.277736572,-11.78773733,-5.935458678,-3.570514906 -2123,L135T,-0.061223034,-0.009615767,-0.015524672,0.002768015,-1.77295641,0.025871492,-0.071176323,-0.051269745,0.032833041,-0.007684469,-0.011547065,0.011375178,-0.042424521,0.003879482,0.001656547,-1.482085631,-2.063827189,0.64119709,1.318693171,-8.406645378,-9.007511322,-9.84318692,-6.777353172,-8.376973969,-8.028201508,-6.563926052,-3.884525252 -2124,L135W,-0.023233632,-0.01870029,-0.712643781,-1.724436773,-2.662718331,0.026094698,0.004379128,-0.050846392,-0.028569748,-0.038741488,0.001340909,-0.447769792,-0.97751777,-1.64030605,-1.808567496,-2.632974969,-2.692461692,1.716388821,0.862657053,-9.355307057,-9.383733772,-9.918236801,-9.177507729,-7.676531036,-10.62052595,-7.063058528,-2.745522269 -2125,L135V,0.035417055,-0.005919798,0.033200828,0.031691953,-0.036550333,0.003850098,0.024684172,0.046149937,-0.015398709,-0.014764977,0.002925382,0.024532592,0.041869063,-0.003382501,0.066766407,-0.047415845,-0.02568482,1.415812981,2.602021313,-4.624903035,-5.070366783,-5.662694664,-3.246710335,-5.019648628,-4.125094765,-3.904763051,-1.390009972 -2126,L135Y,0.012562362,-0.000852569,0.003671587,-1.28702811,-2.43111952,0.050933294,0.041564558,-0.016439834,-0.008733995,-0.070080839,0.068375701,-0.020146229,0.027489403,-1.308678598,-1.265377621,-3.031725985,-1.830513055,0.801065692,0.728726849,-7.763029227,-8.572352875,-7.999037819,-7.599189705,-6.751853973,-7.892711761,-5.809777577,-4.034836862 -2127,L136A,-0.047977402,0.00928127,-0.017677571,-0.125519591,-1.717249236,0.012444281,-0.040676587,-0.055278216,0.044319726,0.003358821,0.015203719,-0.001931135,-0.033424006,0.012688931,-0.263728112,-1.946422787,-1.488075684,0.680394701,1.298568349,-7.131843488,-5.85375518,-7.153600662,-6.327904861,-7.820993301,-8.502963432,-5.382692475,-4.1737922 -2128,L136C,-0.113055808,-0.03131713,-0.099447597,-1.307198378,-2.753682394,0.011941016,-0.129508249,-0.096603366,-0.001686899,0.036046841,-0.0986811,-0.012428628,-0.186466566,-1.150514658,-1.463882097,-2.213269771,-3.294095016,0.833857317,0.754900057,-8.707652716,-8.367589943,-8.680756943,-8.572706841,-9.934712555,-7.982497299,-7.05935192,-4.103830045 -2129,L136E,-0.035618852,-0.789348506,-2.084277019,-2.396207913,-3.025057795,-0.025552081,-0.011584163,-0.05965354,0.045593757,-0.337396557,-1.241300455,-1.648276351,-2.520277686,-2.713322505,-2.079093321,-2.787073003,-3.263042586,1.327518256,0.069593618,-12.03008268,-10.76053468,-12.20629511,-11.63861162,-13.28215435,-12.26281763,-9.762993266,-10.45371609 -2130,L136D,-0.072914699,-1.455973755,-2.338652659,-2.713052922,-2.768838785,0.074176139,-0.040743257,-0.105086141,0.065907432,-1.501113314,-1.410834195,-2.061280106,-2.616025212,-2.28122822,-3.144877624,-2.656008713,-2.881668857,-0.271717848,-0.947047291,-12.85720479,-12.21537987,-13.03692766,-12.255578,-14.09393658,-12.68420184,-9.762993266,-10.45371609 -2131,L136G,-0.061058491,-0.022520349,-1.157233897,-2.076595831,-3.003875111,0.021011738,-0.046717056,-0.075399926,0.036435712,-0.004109567,-0.04093113,-1.092033257,-1.222434536,-1.804522985,-2.348668677,-2.621260316,-3.386489906,2.459935651,1.127724855,-11.6806555,-11.111665,-11.45060035,-11.25702106,-12.47563342,-12.10835767,-9.043111978,-7.87811875 -2132,L136F,-0.057483584,-0.703158204,-1.724271837,-2.681837811,-2.825669304,0.019302395,-0.07564674,-0.039320428,0.099180835,-0.480647593,-0.925668814,-1.595232742,-1.853310932,-2.555543546,-2.808132076,-2.328264048,-3.323074559,1.644658263,0.169514665,-9.440853313,-9.174938179,-8.878201736,-9.448491074,-10.09091125,-9.611724319,-7.488051102,-5.502519691 -2133,L136I,0.03500675,0.014234416,-0.010748454,0.045077481,-0.174964849,-0.031483614,0.039529694,0.030483805,0.055072857,0.039567842,-0.01109901,-0.011062556,-0.010434352,0.025922619,0.064232342,-0.156499002,-0.193430695,1.220572632,2.066951262,-3.114348335,-2.10352832,-3.616627937,-3.221559196,-3.887352203,-2.742674019,-3.720659491,-1.92446127 -2134,L136H,-0.133611849,-0.961515654,-2.187029892,-2.50685792,-2.539765038,0.055439369,-0.123544906,-0.143678791,0.066465026,-0.67081086,-1.252220447,-1.991030681,-2.383029102,-2.454016844,-2.559698995,-3.129827333,-1.949702742,1.490618306,-0.113570198,-12.88937807,-11.65083229,-12.62560618,-13.14513167,-13.73309621,-13.29222398,-9.762993266,-10.45371609 -2135,L136K,0.032910394,-1.73043469,-2.014473315,-2.476919208,-2.532705071,0.047366728,0.100061382,-0.034240594,0.093428506,-1.699124393,-1.761744986,-2.192344395,-1.836602235,-2.111262514,-2.842575901,-2.185013011,-2.88039713,-0.697728144,-1.062722563,-12.07154769,-11.28681774,-12.5124899,-11.78379061,-12.48402549,-12.2906147,-9.762993266,-10.45371609 -2136,L136M,-0.029343821,-0.009509011,-0.024946339,-0.002533488,-1.15861749,0.035162414,-0.041315545,-0.017372096,0.01236855,0.002067072,-0.021085093,-0.02502706,-0.024865618,0.009943671,-0.015010646,-0.686702458,-1.630532521,0.919099064,1.451958208,-3.941644365,-3.630144768,-3.65348008,-4.716066772,-3.926100258,-3.782429947,-5.103221506,-2.821346434 -2137,L136N,-0.001632136,-0.484794756,-1.588947401,-2.777542129,-3.07188862,0.025381346,0.042447398,-0.045711669,0.015388639,-0.304399263,-0.665190248,-1.503348853,-1.674545948,-2.175594639,-3.379489619,-2.726466391,-3.417310848,1.457219834,0.158399669,-10.95537372,-10.46876717,-11.01204106,-10.99690937,-12.07986827,-10.21928275,-7.965230671,-5.198272622 -2138,L136Q,-0.12448723,-0.552065837,-1.688036626,-2.562436889,-2.618222752,0.003310123,-0.046745076,-0.202229383,0.140762384,-0.13627484,-0.967856833,-1.464127449,-1.911945802,-2.286135555,-2.838738222,-2.359886052,-2.876559451,0.935169327,0.066725684,-10.16148378,-8.930022079,-10.65096381,-10.10465358,-9.999408379,-11.12237106,-7.938757164,-7.029747338 -2139,L136P,-0.061274714,-1.51525225,-2.131193669,-2.384797528,-3.068219645,0.023570315,-0.044339724,-0.078209704,0.005532028,-1.462865425,-1.567639075,-2.033251382,-2.229135956,-2.077108237,-2.692486819,-3.008191232,-3.128248057,3.250659202,0.881743811,-12.02477847,-11.32305422,-11.98575116,-11.44825673,-13.25956449,-12.10726572,-9.74733258,-10.38510711 -2140,L136S,-0.032698547,-0.0149125,-1.081950833,-1.981957552,-2.769350458,0.042260005,0.008831511,-0.074228604,0.083328179,-0.006319581,-0.023505419,-0.983593851,-1.180307814,-1.83343105,-2.130484053,-2.739690461,-2.799010455,2.359781327,1.071347823,-9.628428735,-8.825515755,-9.487181686,-9.525306801,-10.63305678,-9.671082657,-7.669048796,-5.858593899 -2141,L136R,-0.088540725,-1.489062885,-2.334851848,-2.288505153,-3.417355034,0.018298926,-0.064954425,-0.112127024,-0.034450625,-1.548717559,-1.429408211,-2.079726122,-2.589977573,-1.89390889,-2.683101415,-2.937696165,-3.897013903,-0.199646261,-0.997231489,-12.03356076,-11.51466544,-11.85562979,-11.75152725,-12.5081244,-12.5378569,-9.762993266,-10.45371609 -2142,L136T,-0.044930806,-0.018432716,-0.034729245,-1.511994107,-2.49032899,0.041582012,-0.028604808,-0.061256804,0.042104698,-0.000748092,-0.03611734,-0.030387585,-0.039070905,-1.268203419,-1.755784795,-2.228010564,-2.752647416,0.859803369,0.736126811,-8.839815788,-8.246984177,-9.612352806,-8.502282845,-8.686276031,-9.151183083,-6.572016099,-5.751164535 -2143,L136W,-0.09308815,-1.752760056,-2.348315589,-2.847654588,-2.792516077,0.015483999,-0.0678006,-0.118375699,-0.031369569,-1.709389256,-1.796130856,-2.237371365,-2.459259812,-2.105136961,-3.590172215,-2.434159964,-3.150872189,-0.482302198,-1.09202305,-11.63108162,-10.90380845,-11.0684702,-11.32970312,-12.80800862,-12.04541773,-9.017207664,-7.87811875 -2144,L136V,-0.035246588,-0.009182113,-0.040336823,0.002743843,-0.906487138,0.040550343,-0.035048036,-0.03544514,0.057409726,0.011960223,-0.030324448,-0.001086548,-0.079587097,0.03987811,-0.034390424,-0.725237498,-1.087736777,0.457052479,1.353846929,-3.59190085,-2.259235275,-3.610065979,-3.217830475,-4.880787399,-3.991585121,-3.398659315,-2.062467492 -2145,L136Y,-0.030087677,-1.751926258,-2.36257114,-2.776562026,-3.181832892,0.0258452,0.036554633,-0.096729986,0.009255314,-1.871550698,-1.632301817,-2.665800696,-2.059341584,-2.186778806,-3.366345246,-2.959499308,-3.404166475,-0.455607935,-1.093465696,-12.52745262,-11.67977261,-12.29079562,-12.65009378,-13.26518274,-12.75141833,-8.875480134,-7.87811875 -2146,L137A,-0.059570186,-0.017688806,-0.029302323,-0.017461453,-1.775437387,0.043049642,-0.047382848,-0.071757523,0.330993219,0.000985053,-0.036362665,-0.020735485,-0.03786916,0.021220889,-0.056143795,-1.608129146,-1.942745627,1.061440403,1.346031302,-8.162671628,-8.174486465,-8.809668816,-7.404939079,-7.465432045,-8.958831734,-5.982805693,-3.794232667 -2147,L137C,-0.048967339,-0.037603284,-0.047532978,-0.170590627,-1.808855586,0.081004982,0.008398913,-0.10633359,0.234083206,0.012358085,-0.087564652,-0.037969254,-0.057096702,-0.046426989,-0.294754265,-2.088854525,-1.528856646,0.60703955,1.287184767,-10.97683732,-11.31605009,-10.47656591,-12.42564502,-9.920069519,-10.74585605,-8.342710653,-5.813794026 -2148,L137E,-0.058991602,0.025528936,-0.019226826,-1.023992586,-2.885000446,0.057346371,-0.032574723,-0.08540848,-0.021189299,0.052137575,-0.001079703,0.005559413,-0.044013064,-0.513327443,-1.534657728,-2.733067882,-3.03693301,1.089601281,0.981572305,-11.47701017,-11.59474796,-11.46526794,-11.93960304,-10.71418007,-11.67125184,-7.853488484,-5.553313135 -2149,L137D,-0.008079952,-0.344473468,-1.507554579,-2.07133342,-3.145786752,0.065983242,0.011982738,-0.028142641,0.507084478,-0.094638326,-0.59430861,-1.45213329,-1.562975867,-1.920410152,-2.222256688,-2.917759313,-3.37381419,2.582229418,1.078781934,-13.71807731,-13.60663083,-14.00673497,-14.11059231,-12.67638992,-14.19003853,-10.171095,-9.715937357 -2150,L137G,-0.037342002,-0.004236591,-0.046279539,-1.088081223,-2.270538407,0.057072169,-0.021038887,-0.053645116,0.054322569,-0.011380731,0.002907549,-0.060599125,-0.031959952,-0.674595548,-1.501566897,-2.195657834,-2.34541898,1.721526992,1.329705029,-11.83380367,-12.44707608,-11.49548137,-11.30909789,-11.16332382,-12.75403921,-7.708159515,-4.862640782 -2151,L137F,0.018682968,0.010123453,0.036700991,0.020510729,-0.950327725,0.129616703,0.05532672,-0.017960784,0.029963223,-0.026176527,0.046423433,0.015138875,0.058263107,0.045627563,-0.004606105,-0.761463254,-1.139192195,0.582916593,1.366205451,-6.908805071,-7.754445572,-5.817833855,-8.553684753,-6.113210518,-6.304850655,-4.240069419,-1.419722517 -2152,L137I,0.005518567,-0.049275277,-0.003329892,0.045246331,-0.155949816,0.017372823,0.034788184,-0.02375105,0.176091259,-0.028526187,-0.070024367,0.022054515,-0.028714298,0.032424087,0.058068575,-0.123266251,-0.18863338,1.196778844,2.181634038,-4.889278819,-4.707169441,-4.784677605,-3.540926666,-5.208375877,-6.205244507,-4.167821289,-0.501860826 -2153,L137H,-0.025899914,-0.034918216,-0.069774329,-1.561841382,-2.716401962,0.066766967,-0.010502492,-0.041297336,0.378417869,-0.039828896,-0.030007536,-0.100143293,-0.039405365,-1.350077333,-1.77360543,-2.718494356,-2.714309567,0.918048883,0.739824929,-11.82039254,-11.00237223,-11.63715829,-13.79455672,-9.94888459,-12.71899088,-7.301555472,-5.489362878 -2154,L137K,-0.029615044,-0.094164326,-1.819391843,-2.481318007,-3.006079023,0.108637071,0.010184707,-0.069414795,-0.06694679,-0.17246611,-0.015862542,-1.600385019,-2.038398666,-1.88361578,-3.079020234,-2.822972994,-3.189185051,2.769547998,1.13690377,-13.41062022,-13.40594216,-13.76779122,-13.82232706,-11.85139246,-14.20564821,-8.939746547,-6.714215116 -2155,L137M,-0.00460215,-0.01866199,-0.080387198,-0.025088762,-0.14725794,0.058706721,0.011762048,-0.020966347,0.21901946,0.012652848,-0.049976828,-0.117599698,-0.043174697,-0.035911119,-0.014266404,-0.121061781,-0.173454099,1.654077292,2.515558297,-4.847081284,-5.139874443,-4.474568428,-4.352966621,-4.964768867,-5.303228058,-4.979974167,-2.090362188 -2156,L137N,-0.034257837,0.015508491,0.008805354,-0.97297948,-2.765156307,0.055053434,-0.006282329,-0.062233345,0.029963223,0.067016575,-0.035999593,0.020146615,-0.002535908,-0.512136259,-1.4338227,-2.051826645,-3.478485969,1.715318251,1.373429946,-13.3217138,-13.66070147,-12.71609892,-14.67506841,-12.11220952,-13.44449068,-10.171095,-9.715937357 -2157,L137Q,-0.040344377,0.000403022,-0.070720994,-0.505934979,-2.069203197,0.054967973,-0.037559413,-0.04312934,0.081115746,-0.015649736,0.016455779,-0.097816642,-0.043625345,-0.157886805,-0.853983152,-1.76315697,-2.375249424,1.198357464,1.346886771,-11.12768213,-11.81137198,-11.33487238,-11.62717197,-8.484181305,-12.380813,-7.501002281,-2.888098375 -2158,L137P,-0.018884048,-1.468272325,-2.020665783,-2.22412534,-2.743316825,0.066169539,-0.013662921,-0.024105174,0.277410391,-1.496621212,-1.439923437,-1.898690448,-2.142641117,-2.061781355,-2.386469324,-2.572463944,-2.914169706,-0.408588164,-0.899299996,-13.17848505,-13.54812634,-12.93964551,-13.71106385,-12.3459126,-13.34767696,-10.171095,-9.715937357 -2159,L137S,-0.053561657,0.003637545,-0.019523197,0.001497737,-1.799622821,0.08319233,-0.026517658,-0.080605655,0.09123288,0.028099724,-0.020824635,0.016222999,-0.055269393,0.060843612,-0.057848139,-1.582282489,-2.016963152,0.440264997,1.30604665,-9.802663397,-10.29355078,-9.505205582,-10.50366345,-9.044688286,-9.666208885,-7.057605386,-4.443296035 -2160,L137R,-0.057799387,-0.822449487,-1.92787599,-2.474269126,-2.957709252,0.067388749,-0.035646852,-0.079951922,0.302964495,-0.63032153,-1.014577444,-1.936251189,-1.919500791,-2.282063934,-2.666474317,-2.69508187,-3.220336634,0.164576139,-0.542821237,-12.36927197,-12.13331377,-12.2946601,-13.15176981,-10.78019717,-13.48641898,-7.99496215,-4.655326925 -2161,L137T,-0.012596648,-0.031520483,-0.01765207,-0.003388147,-1.083467725,0.038812558,-0.023216565,-0.001976731,0.375805563,-0.039194553,-0.023846412,-0.028570123,-0.006734017,-0.004822058,-0.001954236,-0.846132858,-1.320802592,0.489394322,1.345857211,-7.688504807,-8.000066414,-9.032793381,-7.214277603,-6.977488815,-7.21789782,-5.724993663,-3.661306259 -2162,L137W,-0.076656653,-0.028338846,-0.017399264,-1.487507702,-2.888567291,0.042404742,-0.057745791,-0.095567514,0.198367654,0.025985205,-0.082662897,0.013834523,-0.048633051,-1.095151733,-1.879863671,-2.464886798,-3.312247783,0.645899981,0.732335813,-11.05812986,-10.85102834,-9.857675934,-12.8840747,-9.449468887,-12.24840146,-7.254605268,-4.505841748 -2163,L137V,0.001434249,0.017019573,0.012496782,0.001146851,-0.698817295,0.023071781,-0.004336339,0.007204836,-0.053011012,0.030554849,0.003484297,-0.002203665,0.027197229,0.010547091,-0.00825339,-0.546822623,-0.850811967,0.676998478,1.417117489,-5.499788724,-6.183608322,-6.523427696,-4.395052444,-4.022797218,-6.374057938,-5.422165484,-2.414711155 -2164,L137Y,-0.038573701,0.007598906,-0.062500844,-0.019695795,-0.46206087,0.192944298,-0.030018146,-0.047129256,0.029963223,0.026225927,-0.011028116,-0.037343034,-0.087658654,-0.021549782,-0.017841807,-0.349892162,-0.574229577,1.306619061,1.890859578,-10.98657814,-11.53160198,-10.32337232,-12.60866045,-9.083337936,-11.38591801,-7.0166262,-4.612125506 -2165,T138A,0.047300826,0.033895921,0.03309556,0.037385547,0.009399046,-0.033673406,0.023038812,0.07156284,-0.018499736,-0.007626371,0.075418212,0.025814936,0.040376184,0.021642391,0.053128703,-0.007201429,0.025999521,1.198459933,2.588343014,-0.619875897,-0.702156631,-0.204951721,-0.380359764,-0.907214874,-0.904696495,-2.748109517,1.476183038 -2166,T138C,0.031323059,0.031112032,0.070318654,0.09050691,-0.34071976,0.041745902,0.048508618,0.0141375,-0.022660938,0.03477586,0.027448204,0.016868872,0.123768435,0.091473198,0.089540621,-0.137380561,-0.544058958,1.16738291,2.110325856,-5.701370988,-4.881204811,-6.029146202,-5.853961655,-5.848124725,-5.894417549,-7.082669196,-3.73963013 -2167,T138E,0.043012374,0.029564128,0.061262831,0.064568463,0.009167938,0.045496346,0.020852711,0.065172037,-0.021144134,-0.061684693,0.120812949,0.075409837,0.047115824,0.092176001,0.036960925,0.017746939,0.000588937,1.252694668,2.763475511,-0.115890463,-0.711804497,-0.214925835,0.509771454,0.285982018,-0.448475456,-1.871448406,1.793360437 -2168,T138D,0.045187576,0.0103214,0.04738805,0.032292424,-0.03346632,-0.01512057,0.035489412,0.054885739,-0.023030752,-0.036762645,0.057405445,0.024052762,0.070723337,-0.000714056,0.065298903,0.032118804,-0.099051444,1.195477376,2.805787442,-1.251198177,-0.918448929,-1.446336235,-1.24758419,-0.73636747,-1.907254059,-3.011889671,2.283162135 -2169,T138G,0.012043052,0.016113486,0.022302798,0.044071208,-0.000496644,-0.029698976,-0.017221534,0.041307637,-0.019880025,-0.005029777,0.037256748,0.037313069,0.007292526,0.053595372,0.034547043,-0.019656159,0.018662872,1.680490028,3.618873133,-3.020061546,-1.632515892,-3.15940416,-3.494865265,-2.426443985,-4.38707843,-3.933241879,0.493101668 -2170,T138F,-0.109332718,-0.101073277,-0.030072788,-0.032378236,-0.20625038,0.004086483,-0.131105323,-0.087560112,0.00703297,-0.013094493,-0.189052061,0.04975692,-0.109902496,0.018471374,-0.083227845,-0.092780228,-0.319720531,1.280358879,2.291602782,-5.889674367,-5.996547592,-6.556089058,-6.237256683,-4.569076958,-6.089401543,-6.919952167,-3.801646251 -2171,T138I,0.088651516,0.090998368,0.100352447,0.102389142,-0.022101148,0.023902534,0.079898032,0.097404999,-0.016398604,0.059483755,0.122512981,0.112570631,0.088134263,0.051854234,0.152924049,-0.029806966,-0.014395329,1.182217169,2.487005351,-6.503337865,-6.738075821,-6.88703685,-7.085261696,-5.580189926,-6.226125031,-7.578886263,-4.668691242 -2172,T138H,-0.002823283,-0.032448141,0.066558357,0.035001093,-0.048618792,0.026129749,-0.031164378,0.025517812,0.003584874,0.046157808,-0.11105409,0.086593031,0.046523683,0.074526768,-0.004524582,0.052710358,-0.149947942,1.029557196,2.74375402,-3.258894714,-2.937899055,-4.229243988,-2.903146004,-1.861804543,-4.362379982,-3.662103498,-0.181824249 -2173,T138K,0.188762501,0.127911637,0.172580737,0.140823749,0.081894723,-0.163015759,0.171044082,0.206480919,0.069320617,0.136096794,0.11972648,0.109039762,0.236121712,0.135647568,0.145999929,0.140520255,0.023269191,1.012074933,2.973211769,-0.74079278,-0.754550018,-1.32689975,-0.413400566,-0.122747307,-1.086366257,-2.18914918,1.521277102 -2174,T138M,0.063857459,0.027988404,0.110062385,0.095150172,0.003602955,-0.000510161,0.085296355,0.042418563,0.060945994,0.059049678,-0.00307287,0.130048142,0.090076628,0.108417915,0.081882429,0.047911475,-0.040705566,1.054790213,2.757281957,-6.478669884,-6.622152229,-6.718733109,-6.883342415,-5.842077713,-6.327043953,-7.486823558,-4.785134558 -2175,T138L,0.035639024,0.006976589,0.073702054,0.098962322,-0.04413855,0.032603291,-0.019598089,0.090876136,-0.051850585,0.027868593,-0.013915415,0.078398552,0.069005556,0.091788678,0.106135966,0.003774597,-0.092051697,1.191048489,2.822820842,-5.143076768,-5.719406349,-5.926114998,-5.739197136,-4.259243896,-4.071421463,-6.157196101,-2.419191085 -2176,T138N,0.101419925,0.078614015,0.098621125,0.138190956,-0.011422069,-0.046585455,0.041236768,0.161603081,-0.01257805,0.051045362,0.106182667,0.109185035,0.088057214,0.183161729,0.093220182,0.100860236,-0.123704374,1.080463619,2.978678781,-1.25742303,-1.180660187,-1.512579697,-1.140663269,-0.688760696,-1.764451302,-3.869707775,0.460018717 -2177,T138Q,0.003484266,-0.039107189,0.0927326,0.107969788,-0.022462671,0.138802931,-0.030004658,0.036973189,-0.050265497,0.005126093,-0.08334047,0.062131821,0.123333379,0.04754547,0.168394106,0.006952867,-0.051878209,1.462503487,2.934736795,-1.465633731,-1.760616638,-1.986450806,-1.290158478,-0.871731934,-1.4192108,-2.569861971,0.317770603 -2178,T138P,-0.01933727,-0.003135185,0.032505371,0.023976012,-1.637176164,0.093063421,-0.026334899,-0.01233964,-0.0537333,0.000630022,-0.006900391,0.060587192,0.00442355,0.05522816,-0.007276137,-1.460567173,-1.813785154,0.133562332,1.300167792,-4.711331203,-4.730882118,-4.86491111,-4.168256203,-3.697396065,-6.095210518,-4.723126262,-0.496265459 -2179,T138S,0.028018352,0.026674087,0.056585435,0.037171261,-0.005663247,-0.011422954,-0.004388116,0.06042482,0.003586941,-0.013252229,0.066600403,0.053957973,0.059212896,0.032250089,0.042092433,-0.017987559,0.006661066,1.285028742,2.621503574,0.11408441,0.445953514,-0.157487549,-0.041675995,-0.258152901,0.581784981,-0.745813936,0.231032293 -2180,T138R,0.040804709,0.011912369,0.069178457,0.067143603,-0.014866236,-0.045333987,-0.010243179,0.091852596,-0.046667684,0.023845137,-0.0000204,0.066280107,0.072076807,0.089207087,0.045080118,0.018303719,-0.04803619,1.680490028,3.618873133,-2.406187067,-1.454644073,-3.480501778,-3.049792625,-0.69397155,-3.352025307,-3.618059727,2.275344989 -2181,T138W,0.037425821,0.035226216,0.032468781,0.074664026,-0.048985813,-0.037772997,0.010948853,0.063902788,0.035052983,0.017582098,0.052870334,0.050834868,0.014102694,0.056105198,0.093222853,0.018793376,-0.116765001,1.234677653,2.772036534,-6.049598035,-5.256636841,-6.253641373,-6.571203102,-3.976516472,-8.189992386,-6.13662106,-2.026832317 -2182,T138V,-0.007781829,0.008948164,0.002520962,0.014650849,-0.070479439,0.00930826,-0.017767595,0.002203937,0.04425778,-0.014206189,0.032102517,0.015230802,-0.010188878,0.039015203,-0.009713505,-0.053140767,-0.08781811,1.151075495,2.271329932,-4.500710762,-4.95806839,-4.431795967,-5.18366317,-3.369942093,-4.56008419,-5.559889028,-2.198940296 -2183,T138Y,-0.042695916,-0.015842156,0.090894558,0.043143909,-0.063154918,-0.039259692,-0.068316717,-0.017075115,0.01703859,0.019052382,-0.050736694,0.124309034,0.057480081,0.12422468,-0.037936863,-0.001711975,-0.124597861,1.248566977,2.72936441,-5.565269263,-5.387578674,-6.194828827,-5.440557869,-3.927574081,-6.875806862,-5.826258988,-2.98310817 -2184,T139A,-0.068814666,-0.084822052,-0.028455638,-0.061575804,-0.021554077,-0.006237437,-0.046789933,-0.090839399,-0.077223491,0.016809625,-0.186453729,0.046408019,-0.103319294,0.055367006,-0.178518613,-0.001767815,-0.041340338,1.124142478,2.527128261,-1.704429431,-1.263338905,-1.353040962,-2.19481002,-1.755653038,-1.95530423,-3.099639194,0.594066046 -2185,T139C,-0.038255576,-0.024917526,0.00944258,-0.01251257,-0.169138366,0.105832208,-0.025060911,-0.05145024,-0.012773968,0.046075772,-0.095910824,0.110043747,-0.091158587,0.115704861,-0.14073,-0.090883428,-0.247393303,1.147806515,2.297331698,-8.001510944,-6.596403114,-8.006027832,-8.985307495,-8.877137398,-7.542678879,-7.353744607,-3.600680694 -2186,T139E,0.012108842,-0.013135739,0.049405877,0.015980112,0.053101457,-0.050680974,0.012814103,0.011403581,-0.014195555,0.067278439,-0.093549917,0.078359691,0.020452062,0.07627919,-0.044318966,0.09944827,0.006754643,1.266944575,3.040825888,-5.680054819,-4.043139641,-6.1179767,-7.631993713,-6.273864815,-4.333299225,-4.953453838,0.96762564 -2187,T139D,-0.041222175,-0.054091245,0.024893094,0.027184041,-0.217867719,-0.001273039,0.020034042,-0.102478391,-0.012282685,0.029811928,-0.137994417,0.090402109,-0.040615922,0.128451132,-0.074083051,-0.087673283,-0.348062155,1.402202694,2.575328355,-7.887607301,-5.249495743,-8.858196541,-8.904714287,-9.406368324,-7.019261612,-6.292161615,-0.971276204 -2188,T139G,-0.033385256,-0.071951285,-0.027303179,-0.042742404,-0.117638352,-0.023782131,-0.014934061,-0.051836451,-0.031479599,-0.021917256,-0.121985313,-0.006612505,-0.047993853,0.033266076,-0.118750884,-0.077655636,-0.157621067,1.339728546,2.429168173,-4.869552748,-4.109223595,-4.39698864,-5.069132408,-6.063202782,-4.709216316,-5.200381608,-2.146168406 -2189,T139F,-0.085580215,-0.064471739,-0.016598821,-0.073303858,-1.379021899,0.020416706,-0.078990414,-0.092170016,-0.046436303,-0.041392685,-0.087550792,-0.006269869,-0.026927773,0.013806739,-0.160414455,-1.247995213,-1.510048584,0.671421705,1.333507755,-8.977303757,-8.195932915,-9.480024185,-9.597422218,-9.69720137,-7.915938095,-6.22776193,-1.050381707 -2190,T139I,-0.101361972,-0.046653366,-0.032759277,-0.079258122,-0.035725821,-0.035481083,-0.096387961,-0.106335983,0.014339796,0.045102093,-0.138408824,-0.000694911,-0.064823643,0.029548513,-0.188064756,0.00250707,-0.073958711,1.244514001,2.707780622,-7.272871365,-5.495509689,-8.765267921,-7.857451538,-7.962367828,-6.28375985,-5.895342155,-0.329813973 -2191,T139H,-0.11503412,-0.132290938,-0.081671372,-0.106540068,-0.336643603,-0.027777918,-0.112495156,-0.117573084,-0.0468611,-0.081771847,-0.182810029,-0.019938002,-0.143404741,0.009718898,-0.222799033,-0.234931691,-0.438355515,1.809006073,2.424468709,-4.770661147,-4.918910202,-4.298344734,-5.359063507,-5.878014618,-3.398972672,-5.168105079,-0.314568917 -2192,T139K,0.049809395,-0.076779879,-0.011363966,-0.019848901,-1.134124571,-0.000677767,0.066716829,0.03290196,-0.033428787,-0.033423755,-0.120136002,-0.06875932,0.046031388,0.05150496,-0.091202761,-0.971251605,-1.296997537,0.65130628,1.351647927,-4.853296548,-4.029463821,-3.425359406,-5.925925507,-5.662410675,-5.223323334,-3.491674984,0.253644947 -2193,T139M,0.007613917,-0.090644928,-0.012907674,0.028126169,-0.095383625,-0.057320323,-0.015770139,0.030997972,-0.088829173,0.003818866,-0.185108722,0.027951479,-0.053766826,0.084631016,-0.028378679,-0.028609887,-0.162157363,1.361151851,2.636384469,-7.465278989,-5.680759407,-8.31283355,-9.44532695,-7.044448868,-6.843026169,-5.589018082,-0.6724231 -2194,T139L,-0.066674262,-0.11065359,-0.008909528,-0.058212858,-0.040313798,-0.001883848,-0.050620774,-0.082727749,-0.02180566,-0.008000286,-0.213306893,0.01991538,-0.037734435,0.065571084,-0.1819968,0.031705481,-0.112333076,1.169188176,2.806454629,-7.335669307,-5.406129532,-8.432587692,-8.07676017,-9.124375587,-5.638493553,-4.093426698,1.766956728 -2195,T139N,-0.036150597,-0.061296354,0.004417874,-0.01934973,-0.081692222,-0.077122364,-0.029644077,-0.042657117,-0.049151488,0.00799909,-0.130591797,0.019685427,-0.010849679,0.04908873,-0.087788189,-0.056070283,-0.107314161,1.213343559,2.398956387,-4.289839668,-3.072246208,-4.738136726,-4.78121582,-5.543461174,-3.314138412,-5.260512516,-1.749346023 -2196,T139Q,-0.007160632,-0.092551175,0.027528917,-0.009708671,-0.02812127,-0.020176265,0.030082224,-0.044403488,0.095107619,-0.002679427,-0.182422923,0.037190215,0.017867618,0.10425724,-0.123674581,0.07076755,-0.127010089,1.210047111,2.96515002,-4.957104672,-4.529134132,-4.366084724,-5.959701355,-6.028862793,-3.901740356,-4.105781196,0.31279392 -2197,T139P,-0.081039537,-0.050579471,-0.021264476,-1.347255419,-2.120888247,0.048276014,-0.047742681,-0.114336392,-0.022486701,0.008828978,-0.109987919,0.021271925,-0.063800876,-1.045726758,-1.648784079,-2.20208922,-2.039687273,2.083473241,1.423019902,-6.112336208,-4.714641647,-6.524118423,-7.468125092,-6.6979776,-5.156818275,-6.703137936,-3.511979155 -2198,T139S,-0.044946523,-0.064014906,0.000191143,-0.03940912,0.024660069,-0.036218837,-0.036996968,-0.052896077,-0.035628088,0.001802589,-0.129832401,0.066506864,-0.066124578,0.07627919,-0.15509743,0.062573643,-0.013253506,1.067914636,2.733284345,-0.820967345,-0.372434471,-0.534967979,-1.097303017,-1.240348564,-0.859782692,-2.638117652,0.186264688 -2199,T139R,-0.052422042,-0.059192942,-0.001626269,-0.02455481,-0.18923676,0.011926443,-0.035388666,-0.069455418,-0.022998914,0.025477313,-0.143863197,0.046365792,-0.049618329,0.059044661,-0.10815428,-0.097563625,-0.280909894,1.393694966,2.42738618,-3.619595001,-3.290144119,-3.683483253,-4.289686134,-4.36979039,-2.464871109,-4.745185276,1.529801778 -2200,T139W,-0.162740277,-0.137622911,-0.036385424,-0.1111572,-1.634384635,0.061127461,-0.147503133,-0.17797742,-0.012931833,-0.012435938,-0.262809883,0.020708501,-0.093479349,0.044665536,-0.266979935,-1.547464939,-1.72130433,0.141842937,1.299659318,-9.61720569,-8.320450363,-9.399846443,-11.30443879,-10.26024358,-8.801049278,-6.739993601,-2.864572243 -2201,T139V,-0.074843635,-0.105313971,-0.055796759,-0.055646363,-0.055610984,0.052907013,-0.057064889,-0.09262238,-0.005331075,-0.001025076,-0.209602865,0.009613087,-0.121206605,0.064450547,-0.175743273,0.024368041,-0.135590008,1.146717002,2.694846918,-5.692967595,-4.864584244,-6.271646683,-5.785844902,-6.154010246,-5.3887519,-4.380703887,-0.31034032 -2202,T139Y,-0.022793173,-0.03330858,-0.008240303,-0.036428688,-1.324513524,0.072833302,0.019599918,-0.065186263,-0.024926193,0.025004712,-0.091621871,-0.008486739,-0.007993867,0.037975825,-0.1108332,-1.193390513,-1.455636535,0.627909027,1.33311386,-7.7514651,-7.402319672,-7.39843898,-9.13065213,-7.875870613,-6.950044106,-5.708911434,-0.381700702 -2203,I140A,-0.062673111,0.073692535,0.047544496,0.061307204,-1.498297601,0.092635373,0.0694177,-0.194763921,0.020994227,0.095606069,0.051779001,0.022903217,0.072185774,0.085816815,0.036797593,-1.373184258,-1.623410944,0.225454015,1.305838508,-4.391328032,-3.057601669,-4.291975555,-6.626827599,-4.118591888,-3.861643448,-4.459707736,-1.145191496 -2204,I140C,0.060230927,0.020351479,0.022412615,0.012819656,-1.437943051,0.072517243,0.052623242,0.067838611,0.03339708,0.036575926,0.004127031,-0.001297593,0.046122822,0.041573634,-0.015934323,-1.284974926,-1.590911176,0.673691796,1.331636422,-7.051780296,-5.295117378,-6.284349487,-10.78031923,-6.803809967,-6.09530542,-6.064350748,-3.71908382 -2205,I140E,0.069990676,0.016015876,-0.024020345,-1.312140447,-2.106084455,-0.001810865,0.079196425,0.060784927,0.063619971,-0.019683944,0.051715695,-0.02543609,-0.022604599,-1.160437143,-1.46384375,-2.098440118,-2.113728792,2.248885612,1.493137515,-9.076833818,-6.874201668,-9.031281273,-12.42086936,-8.773223419,-8.284593369,-8.094582497,-6.534454729 -2206,I140D,0.03945061,-0.082263398,-1.409062161,-2.237347011,-3.26519342,0.034310776,0.056096632,0.022804588,0.010831252,-0.035594947,-0.128931848,-1.193630939,-1.624493382,-2.151536584,-2.323157437,-2.98039509,-3.54999175,2.162399835,0.766397156,-10.22404447,-7.985114014,-9.895039581,-14.16392251,-9.902371284,-9.173774963,-8.834125656,-8.932049556 -2207,I140G,0.018111691,0.007052982,-0.00685681,-1.010761062,-1.734219462,0.065006024,0.065852203,-0.029628822,0.025782821,-0.014947804,0.029053768,-0.054695415,0.040981795,-0.633551552,-1.387970572,-2.024961508,-1.443477415,1.836396175,1.412117446,-7.442145476,-6.192971458,-6.933194893,-10.33661476,-6.522277443,-7.225668823,-5.912435103,-3.97427313 -2208,I140F,0.099751373,0.035192389,0.058018158,0.048891695,-0.184413504,-0.043800654,0.112191326,0.08731142,0.029792955,0.03247182,0.037912957,0.067053782,0.048982533,0.046496311,0.051287079,-0.146057545,-0.222769462,1.355687929,2.250613978,-4.551839363,-3.371833466,-3.707402824,-7.374999855,-4.147935242,-4.157025429,-3.925736096,-1.757039035 -2209,I140H,0.053201451,0.016202885,-0.010349353,-1.352290775,-2.596333523,0.043106427,0.066838884,0.039564018,0.02484058,-0.009077489,0.041483259,-0.02148576,0.000787054,-0.972012149,-1.7325694,-2.129174735,-3.06349231,2.074338269,1.430597314,-9.007478189,-6.092997498,-8.213595444,-14.82009936,-8.110594025,-7.800104622,-5.785983349,-4.604322027 -2210,I140K,-0.019354467,0.009653039,-0.755288815,-1.583831486,-2.431673968,0.014636233,-0.0176,-0.021108934,0.010156657,0.016915291,0.002390787,-0.545351194,-0.965226435,-1.62751646,-1.540146512,-2.678223715,-2.18512422,1.890822353,0.934578504,-9.948549683,-7.993138504,-9.691270615,-13.35750648,-9.368353477,-9.33247934,-8.834125656,-8.932049556 -2211,I140M,0.087256817,-0.008758017,0.008632844,0.007953198,-0.036978728,-0.018402044,0.091133522,0.083380112,0.044295304,0.008393905,-0.025909938,0.004737968,0.012527719,-0.047732863,0.063639259,-0.076297373,0.002339917,1.340737958,2.341323869,-3.029273608,-2.727958183,-3.076508118,-2.933778069,-2.882379715,-3.525743958,-4.282813613,-2.341671581 -2212,I140L,0.07648165,0.023758593,0.027289618,0.010490571,0.024254683,-0.013618404,0.06943971,0.083523589,0.052960821,0.007124233,0.040392952,0.000148639,0.054430597,0.007452816,0.013528326,0.031525135,0.01698423,1.165838882,2.697555098,-0.387422964,0.130186623,-0.221735603,-0.325719231,-1.102112297,-0.417734314,-1.992379022,0.698512293 -2213,I140N,0.060406195,-0.016507451,-0.023164344,-1.042676006,-2.209628613,-0.007546703,0.071725777,0.049086613,-0.066342223,-0.039693207,0.006678306,-0.067175222,0.020846535,-0.4994415,-1.585910512,-1.93236598,-2.486891245,1.667191505,1.389788981,-8.558362178,-6.272047424,-8.384725624,-12.82717556,-8.061089516,-7.246772766,-6.775764958,-5.464381679 -2214,I140Q,0.03940386,0.002884432,0.00332688,-0.01836465,-1.419250056,0.047185677,0.020449731,0.058357988,0.052300296,-0.008094344,0.013863208,-0.000470343,0.007124102,0.039076823,-0.075806122,-1.509685594,-1.328814517,0.657442112,1.318723729,-7.314276936,-4.372728508,-7.600938065,-11.12410686,-6.80433931,-6.669271935,-5.912103146,-4.136170245 -2215,I140P,0.010490496,-0.550408003,-1.739585811,-2.114375231,-2.74499476,0.052842994,0.019451566,0.001529426,0.044033395,-0.306655117,-0.794160888,-1.967889199,-1.511282423,-2.11961487,-2.109135591,-2.726624627,-2.763364892,1.062682211,-0.085401576,-9.772675694,-8.273721886,-9.620288147,-12.69573434,-9.520983795,-8.752650307,-8.620421317,-8.089070996 -2216,I140S,0.014603686,-0.004987868,-0.022106543,-0.107281797,-1.563681716,0.049911566,0.022490513,0.006716859,-0.013803886,-0.020107364,0.010131628,-0.054945637,0.010732552,-0.027291703,-0.187271891,-1.709754833,-1.417608598,0.776103442,1.315453593,-5.949923315,-4.545573433,-5.940417664,-8.94239341,-5.454378975,-4.866853096,-5.871575873,-3.341591662 -2217,I140R,0.036711934,-0.013907277,-0.650831056,-1.725957907,-2.684032739,0.066570914,0.04275538,0.030668487,0.018860244,-0.020024701,-0.007789853,-0.417364764,-0.884297348,-1.573158797,-1.878757017,-2.231065684,-3.136999794,1.742762866,0.901563003,-9.9022347,-7.218070793,-9.818572411,-14.10194305,-9.578620483,-8.793966766,-7.802581153,-6.534454729 -2218,I140T,0.039628878,-0.017652796,0.018942399,0.014142285,-1.523189597,0.074983535,0.066847596,0.012410159,-0.011487941,-0.009627795,-0.025677797,-0.001511886,0.039396684,0.030898991,-0.002614422,-1.33385877,-1.712520423,0.796043476,1.33819361,-4.633910347,-3.53565287,-4.475618301,-6.287097206,-4.54070282,-4.330480537,-4.799573036,-2.004284907 -2219,I140W,0.020466501,-0.004243987,0.006879734,-0.711455142,-1.753049544,0.079097235,0.055342815,-0.014409813,-0.092348146,0.010445495,-0.018933468,-0.021134384,0.034893852,-0.307455825,-1.115454458,-1.917043004,-1.589056084,1.383927276,1.35019655,-9.60957867,-8.340267883,-8.889114082,-12.83318353,-9.056764656,-8.928563202,-8.834125656,-8.932049556 -2220,I140V,0.08842957,0.014856539,0.036979587,0.010552858,0.015865042,-0.008646863,0.080284825,0.096574315,-0.016226869,0.008047181,0.021665897,0.017817158,0.056142015,-0.016995573,0.038101289,0.022987293,0.00874279,1.192579612,2.685602053,-1.100670506,-0.840864609,-0.857747787,-1.795814629,-1.41168927,-0.597236237,-1.429142235,0.281730067 -2221,I140Y,0.022035723,-0.035699805,-0.027948017,-0.033877029,-0.643092522,0.031796354,0.036691048,0.007380398,0.057789968,-0.026918409,-0.044481201,-0.062293021,0.006396987,-0.029867332,-0.037886726,-0.472539218,-0.813645826,1.49344939,1.86400115,-7.648501627,-5.55498674,-6.482398567,-12.13531704,-6.843241226,-7.22656456,-5.783980304,-3.684561085 -2222,G141A,-0.016246767,0.054323404,0.001276377,-0.000231131,-1.755335207,0.05171659,0.003172164,-0.035665697,0.043272874,0.010986265,0.097660543,-0.023356954,0.025909708,0.014275964,-0.014738226,-1.643029515,-1.867640899,0.699148322,1.314624099,-7.63416008,-7.494508286,-7.834208267,-7.800629227,-7.39154789,-7.649906731,-7.25189471,-6.22765299 -2223,G141C,-0.067496499,0.076379365,-0.016970974,-0.199595243,-1.746883758,0.075836246,-0.052881607,-0.082111391,0.098469907,-0.006895608,0.159654337,0.038043312,-0.071985259,-0.01304904,-0.386141445,-1.70021054,-1.793556975,0.729385756,1.314051961,-9.800131223,-9.637469994,-10.18542661,-9.706120689,-9.687845917,-9.7837929,-8.582593854,-8.656845841 -2224,G141E,-0.037855371,0.030800462,-0.052099048,-0.02534532,-1.398896115,0.059927143,0.01474989,-0.090460631,-0.090978728,0.079508874,-0.01790795,-0.02823143,-0.075966666,0.045263429,-0.095954069,-1.335423007,-1.462369223,0.759389395,1.336104917,-6.445106844,-6.18060688,-6.998313004,-6.175407433,-6.73665741,-6.134549492,-6.201491466,-5.921741668 -2225,G141D,-0.067909527,0.023840993,-0.041156918,0.017771539,-1.723675786,0.092380768,-0.063617029,-0.072202025,0.122492774,-0.019056992,0.066738977,-0.111522539,0.029208703,0.020156564,0.015386513,-0.889592688,-2.557758883,0.74743775,1.374396961,-3.873250647,-3.645155693,-4.115102348,-3.358463181,-4.550142311,-3.697389702,-4.727663171,-3.616531635 -2226,G141F,0.040114643,0.068174543,-0.000114648,-0.984659591,-2.235048401,0.050692995,0.10563984,-0.025410555,-0.027751828,-0.021762885,0.15811197,-0.010247721,0.010018426,-0.605968859,-1.363350322,-1.853380516,-2.616716286,1.862528639,1.472809675,-11.38295504,-10.65978058,-11.98453452,-11.06583293,-11.00121209,-12.20341511,-9.345783834,-10.56086115 -2227,G141I,-0.120222281,0.003405966,-0.003109468,-1.025039782,-2.337303037,0.000638883,-0.135142129,-0.105302432,-0.138450125,0.030373317,-0.023561386,0.083745405,-0.08996434,-0.305145032,-1.744934532,-2.128603248,-2.546002825,1.593285409,1.342960855,-9.135840883,-8.72706987,-10.40629797,-9.709876678,-8.356974762,-8.478985138,-7.45190376,-5.641960555 -2228,G141H,-0.013113225,0.03592757,0.021801546,0.038961832,-1.586028399,0.123103545,0.040280938,-0.066507388,0.023014483,-0.0132111,0.08506624,0.004120059,0.039483032,-0.005058099,0.082981762,-1.593743205,-1.578313592,0.75321606,1.320133877,-8.658708661,-8.415706467,-8.843847351,-8.626537529,-9.560872971,-7.846578987,-8.429084633,-7.998036452 -2229,G141K,-0.097789617,0.075817383,-0.014428483,-0.030623595,-1.367054306,0.057337931,-0.057495494,-0.13808374,-0.231871811,0.055008364,0.096626401,0.08426708,-0.113124045,0.074364019,-0.135611208,-1.399489102,-1.33461951,0.443429755,1.311898188,-5.733889723,-5.619452789,-5.625838402,-6.093531197,-6.704287758,-4.62633847,-5.427061538,-5.181346957 -2230,G141M,-0.046860513,0.039629861,-0.049201916,0.074906312,-1.532986606,0.016183909,-0.023508859,-0.070212167,-0.197212508,-0.034425429,0.113685151,-0.093884543,-0.004519288,0.024891897,0.124920726,-1.59977517,-1.466198041,0.703867818,1.315950193,-10.55450373,-9.987561592,-11.04544693,-11.49914362,-10.07782359,-10.16254291,-8.596394803,-8.088402807 -2231,G141L,-0.027995233,0.089400842,-0.009828929,-0.164416401,-1.747878303,0.042055303,0.005468728,-0.061459193,-0.050376448,0.050409876,0.128391808,0.000480356,-0.020138213,-0.000468893,-0.328363908,-1.838945157,-1.656811448,0.867437486,1.312620857,-10.11876252,-9.975550858,-10.52134386,-10.85500507,-9.790473366,-9.45143943,-8.133323921,-7.297633161 -2232,G141N,-0.069070313,0.005640695,-0.073310871,-0.158982193,-0.71373099,0.175081372,-0.050546634,-0.087593991,0.062424802,-0.148151688,0.159433078,-0.135881885,-0.010739857,-0.068589111,-0.249375275,-0.674979174,-0.752482805,1.219871232,1.565429998,-4.621586218,-4.784200836,-4.709714928,-4.649816223,-5.13473246,-3.829466644,-5.102472371,-4.890675532 -2233,G141Q,0.030117083,0.034721813,-0.070691421,0.002803577,-1.174642188,0.081322023,0.078057512,-0.017823346,-0.106038543,-0.036086213,0.105529839,-0.077061922,-0.06432092,0.03093033,-0.025323176,-1.476497217,-0.872787159,0.327345033,1.305208412,-8.104459341,-7.800983063,-8.03881192,-7.90984761,-8.740981842,-8.031672272,-7.645155713,-7.361082595 -2234,G141P,-0.053865984,0.051472652,-0.018488252,-1.52972003,-2.550557496,0.040977972,-0.015435919,-0.092296049,-0.046656543,0.008616366,0.094328938,-0.008498414,-0.02847809,-1.290330393,-1.769109667,-2.438747657,-2.662367334,0.973049756,0.7536675,-9.198641153,-9.502551041,-9.586049278,-8.821390938,-8.77016803,-9.313046478,-6.634202232,-3.655132131 -2235,G141S,-0.034085453,0.111418406,0.01903371,0.022590172,-1.572262939,0.071782072,0.0004947,-0.068665606,-0.061371697,0.092180467,0.130656344,0.028549002,0.009518418,0.063902764,-0.01872242,-1.454797584,-1.689728294,0.572263649,1.316109343,-5.90490287,-5.615930099,-6.465906853,-6.002451775,-5.627747498,-5.812478127,-5.340712795,-4.545116414 -2236,G141R,-0.040246135,0.023015558,-0.023955763,0.001517167,-1.58238244,0.060374483,-0.016239311,-0.064252958,-0.055729671,0.008035801,0.037995315,-0.020418905,-0.027492621,0.015766437,-0.012732103,-1.657514644,-1.507250236,0.829410439,1.321010994,-6.788199446,-6.569435013,-6.964848137,-6.730031776,-7.886068817,-5.790613487,-6.248632116,-5.423773674 -2237,G141T,-0.057877541,0.012784463,-0.014771596,-0.246644058,-1.95731596,0.075194375,-0.108745552,-0.00700953,0.115250909,0.021779262,0.003789664,0.002791372,-0.032334563,-0.01390963,-0.479378486,-1.784515538,-2.130116382,0.773818313,1.310477267,-7.45193616,-6.883353996,-8.065084167,-7.564050362,-6.811869484,-7.935322792,-6.47515324,-4.615081244 -2238,G141W,-0.022431573,0.01509296,-0.158098756,-1.542783045,-2.472098057,0.110587186,0.028921582,-0.073784728,-0.118022046,-0.021819794,0.052005713,-0.029515631,-0.286681881,-1.309857747,-1.775708343,-2.514865555,-2.429330558,0.732670954,0.723729362,-10.7581419,-10.27614566,-10.90705335,-10.88416222,-11.07091641,-10.65243187,-9.328710494,-10.46766159 -2239,G141V,-0.02126953,-0.012338417,0.000246538,-0.816436534,-1.844794396,0.055715277,0.044242888,-0.086781947,-0.006767336,-0.014170364,-0.01050647,0.003006774,-0.002513698,-0.24957356,-1.383299508,-2.141698546,-1.547890245,1.217750144,1.305482002,-8.306577269,-7.886409218,-9.533538818,-8.706027695,-7.682543655,-7.724366959,-6.833978881,-5.109497341 -2240,G141Y,-0.188018422,-0.021067377,0.037378392,-0.852699087,-2.242010824,0.045803785,-0.172112347,-0.203924497,0.191608121,0.067505385,-0.109640139,0.177797352,-0.103040569,-0.094320442,-1.611077731,-1.770845627,-2.71317602,0.956216725,1.321039201,-10.08119046,-9.727016434,-10.88435323,-9.674218788,-10.11267155,-10.00769231,-8.459784056,-8.088402807 -2241,G142A,-0.007918629,-0.034104733,-0.002959489,-0.715207921,-1.667980374,0.089995638,0.029380546,-0.045217803,0.043908665,-0.051147639,-0.017061827,-0.056922065,0.051003087,-0.322812764,-1.107603077,-1.856181667,-1.479779081,1.461658809,1.370198966,-7.579718086,-7.250038185,-7.215907005,-8.476607567,-7.056878212,-7.899159462,-7.016289966,-6.273001337 -2242,G142C,-0.050761146,-0.007245601,-0.111597383,-1.643032607,-2.370468153,0.158694287,-0.032475146,-0.069047145,-0.074871893,-0.061676275,0.047185074,-0.084060941,-0.139133824,-1.20984229,-2.076222923,-1.977915264,-2.763021041,2.642937279,1.809781851,-11.14399873,-10.5563203,-11.39188991,-12.2497953,-10.29082924,-11.23115888,-9.35014905,-10.85705337 -2243,G142E,0.012007875,-0.014425225,-0.027715574,-0.085481208,-2.143842851,0.112099512,0.068309259,-0.04429351,-0.09066616,-0.010880035,-0.017970414,-0.06635611,0.010924963,-0.030128115,-0.140834301,-1.616731501,-2.670954201,0.696998958,1.315006642,-7.092463037,-6.544968765,-6.953279297,-8.308854576,-6.272642464,-7.382570084,-5.989436282,-5.129622228 -2244,G142D,-0.037139755,-0.109155751,0.045134795,0.012458292,-2.152682452,0.09106566,-0.085035436,0.010755926,-0.007020397,-0.015571872,-0.20273963,0.066327762,0.023941827,0.03816853,-0.013251946,-1.486625053,-2.818739851,0.482061221,1.311838495,-6.245531575,-5.369806404,-6.866564148,-7.200748276,-5.248547112,-6.541991936,-5.484147509,-4.88865803 -2245,G142F,-0.082525868,-0.035119733,-0.958413948,-2.472575911,-2.427977434,0.099356751,-0.063602613,-0.101449123,-0.018218297,0.0503695,-0.120608966,-0.907647864,-1.009180031,-2.231796866,-2.713354955,-2.300899835,-2.555055032,1.806528552,0.637570166,-12.24491685,-11.85713472,-12.66633073,-13.2394419,-11.29817021,-12.16350668,-9.35014905,-10.85705337 -2246,G142I,-0.102734217,-0.465081317,-1.611331635,-2.428267757,-2.534184278,0.159800889,-0.091684495,-0.113783939,-0.067436319,-0.096227804,-0.833934829,-1.906422773,-1.316240496,-2.151390529,-2.705144984,-2.220493498,-2.847875058,1.063628505,-0.047296183,-10.93169438,-10.74536913,-11.27484601,-12.0451904,-9.954308723,-10.63875763,-8.187650882,-7.776074977 -2247,G142H,-0.054401575,-0.059377642,-0.045429303,-0.259108989,-1.944233898,0.112798486,-0.040246866,-0.068556283,-0.018091477,0.000480126,-0.11923541,-0.029728927,-0.061129679,-0.115506175,-0.402711803,-1.938192203,-1.950275593,0.908050571,1.307603874,-10.36928284,-9.757443161,-10.28605537,-11.68717229,-9.28362014,-10.83212322,-8.299737207,-7.776074977 -2248,G142K,-0.03161511,-0.083270858,-0.04902908,-1.341900506,-2.514586481,0.076451929,-0.00779972,-0.055430499,-0.075740482,-0.035235427,-0.131306288,-0.038660748,-0.059397412,-1.094572268,-1.589228743,-2.394124159,-2.635048803,0.83963527,0.755681104,-8.662540465,-8.57718589,-7.853943954,-10.21513865,-7.737710968,-8.928722862,-6.729698685,-5.453153235 -2249,G142M,0.005580048,0.054615438,-0.303590933,-2.10269055,-2.631156092,0.043107993,0.005083008,0.006077087,-0.092428006,0.112776753,-0.003545878,-0.146566145,-0.460615721,-1.438530464,-2.766850636,-2.352731473,-2.90958071,0.835597188,0.717278742,-11.93969234,-11.69991994,-11.79995271,-13.23932696,-10.99054937,-11.9687127,-9.35014905,-10.85705337 -2250,G142L,0.013551728,-0.066283454,-1.275378814,-2.340673341,-3.003561539,0.160271423,0.055107092,-0.028003636,0.001471171,-0.072829368,-0.059737539,-1.168099986,-1.382657641,-2.492248988,-2.189097694,-2.561351957,-3.44577112,0.832023822,0.108815024,-12.05666346,-11.93597468,-11.94419077,-13.28638593,-11.26310127,-11.85366464,-9.35014905,-10.85705337 -2251,G142N,-0.006122411,0.004108888,-0.01963966,-0.014689238,-1.272083085,0.071778185,0.027970857,-0.040215678,-0.04624702,0.005672825,0.002544951,0.011087225,-0.050366545,0.04403601,-0.073414486,-1.403883996,-1.140282174,0.555574898,1.317092617,-7.799908798,-6.684626297,-8.532624069,-8.882508163,-6.834601784,-8.065183678,-6.260274544,-5.728460279 -2252,G142Q,-0.011588764,0.005714159,0.031628617,-1.019387087,-2.542831659,0.096821321,0.003752035,-0.026929563,0.011248873,-0.021372219,0.032800537,0.024130082,0.039127151,-0.424004211,-1.614769962,-2.072890777,-3.012772541,1.547534233,1.347991989,-10.66898906,-10.83950645,-10.11730492,-11.7958629,-9.712838745,-10.8794323,-8.451543846,-7.776074977 -2253,G142P,-0.053400637,-0.047392434,-1.203563266,-2.132097089,-3.086825287,0.102056342,-0.0234348,-0.083366473,-0.004681594,-0.033249783,-0.061535085,-0.857623687,-1.549502845,-1.885882334,-2.378311843,-2.822359738,-3.351290836,2.136914817,0.930725086,-9.270669031,-8.431125984,-10.23634682,-10.26241149,-8.062073753,-9.3613871,-7.242511502,-6.68569624 -2254,G142S,-0.038780581,-0.01984802,-0.016873593,-0.009595067,-1.686527285,0.098363414,-0.01963263,-0.057928532,-0.030830386,-0.014612635,-0.025083404,-0.038303451,0.004556266,-0.000848861,-0.018341272,-1.412001886,-1.961052684,0.593721961,1.320521467,-6.15184527,-5.446897148,-6.31739399,-7.264205231,-5.417370003,-6.313359978,-5.185022817,-4.672779996 -2255,G142R,-0.042044818,-0.029193134,-0.035561606,-1.491082415,-2.438075268,0.069216978,-0.007940768,-0.076148867,0.011136638,-0.002085826,-0.056300442,-0.031385963,-0.039737249,-1.252493095,-1.729671734,-2.376865153,-2.499285382,1.008565821,0.762265709,-9.681279543,-9.632399742,-9.236397751,-10.8740239,-8.477773209,-10.18580311,-7.15470692,-6.531683304 -2256,G142T,-0.08765397,-0.071656831,-0.013367515,-0.074748106,-1.601828004,0.111027755,-0.068567322,-0.106740618,-0.012898788,-0.040050045,-0.103263616,-0.045697176,0.018962147,-0.019823416,-0.129672795,-1.799889505,-1.403766503,0.739051439,1.308293851,-8.102403844,-7.27952729,-8.014841629,-9.354381737,-7.246785408,-8.616483154,-6.216721832,-4.788835844 -2257,G142W,-0.062949421,-0.364546702,-1.7473316,-2.175192098,-2.130593621,0.104795789,-0.016733208,-0.109165634,-0.005952426,-0.047098389,-0.681995015,-1.566934525,-1.927728675,-1.811902281,-2.538481914,-1.881005251,-2.380181991,4.298332589,2.744826203,-11.87994325,-11.26590637,-12.06705408,-13.06177983,-10.99859278,-12.00638319,-9.35014905,-10.85705337 -2258,G142V,-0.006941747,-0.016901748,-1.276927455,-1.645767758,-2.534903025,0.147832321,0.030199741,-0.044083234,-0.062214279,-0.025552091,-0.008251405,-1.234406695,-1.319448214,-1.86934553,-1.422189985,-2.28087118,-2.788934869,3.12628629,1.659614709,-11.27875356,-11.13592869,-11.48950177,-12.25602251,-10.30334683,-11.20896797,-9.00978811,-9.245398002 -2259,G142Y,-0.020395847,-0.002859913,-0.733244031,-1.490110227,-2.786132369,0.164849824,0.021503826,-0.06229552,-0.010708695,-0.005827259,0.000107434,-0.380377832,-1.086110229,-1.470443629,-1.509776824,-2.539546598,-3.032718139,1.651308378,0.892491075,-12.44201434,-12.06116125,-13.11235645,-13.07172317,-11.32951818,-12.63531265,-9.35014905,-10.85705337 -2260,P143A,-0.027449548,0.025518747,-0.017848951,-0.028073294,-1.155561932,0.035648082,-0.005749587,-0.049149508,-0.005985767,-0.000451576,0.05148907,-0.003798981,-0.031898921,-0.033611351,-0.022535237,-1.146633414,-1.164490449,0.666126599,1.339838995,-6.53739415,-6.038025833,-8.748475716,-6.50633815,-5.332448563,-6.061682487,-6.365702676,-2.40374905 -2261,P143C,-0.059361146,0.008437733,-0.00646229,-0.019434292,-1.774256601,0.036847143,-0.048344839,-0.070377452,0.012166999,-0.017189342,0.034064807,0.032404517,-0.045329096,0.003022429,-0.041891012,-1.374011993,-2.174501208,0.685992291,1.327010499,-12.01055073,-12.29039792,-14.56644402,-11.07285207,-10.6918622,-11.43119746,-10.06511847,-6.849734047 -2262,P143E,-0.040004756,0.025175263,-0.046077083,-0.579766279,-2.245986947,0.040978127,0.009048587,-0.089058098,0.065299361,0.007843421,0.042507105,-0.027322773,-0.064831392,-0.219952896,-0.939579661,-1.941145341,-2.550828553,1.24732889,1.33097985,-11.12599111,-10.7982267,-13.49302814,-10.3230258,-9.620823914,-11.39485101,-8.386506725,-3.99851794 -2263,P143D,-0.060209363,0.047597101,-0.325704275,-1.95852858,-2.988158154,0.006362817,-0.066033185,-0.05438554,-0.059639375,0.033937607,0.061256595,-0.164084507,-0.487324042,-1.496003241,-2.421053919,-2.77687708,-3.199439228,1.264451243,0.775584791,-12.65392538,-12.60947099,-15.71249095,-11.88202493,-10.35736584,-12.70827422,-9.123094563,-4.671164283 -2264,P143G,-0.00139505,0.050165626,-0.019464478,-0.035218314,-1.833277047,0.003680445,0.015694003,-0.018484102,-0.042035486,0.004861828,0.095469423,-0.034042914,-0.004886041,0.001782417,-0.072219044,-1.610798354,-2.055755739,0.650401536,1.312397861,-9.519024211,-8.963970726,-12.34241113,-8.479893959,-9.463693588,-8.345151649,-7.638923842,-2.915360291 -2265,P143F,-0.049734357,0.015532533,-0.037831506,-0.930476462,-2.387195776,0.017569422,-0.024534082,-0.074934632,-0.093080096,-0.019773844,0.050838909,-0.000420624,-0.075242387,-0.357615948,-1.503336976,-2.075843915,-2.698547637,1.551706052,1.345293151,-12.0926022,-15.07377172,-14.89256205,-9.611927055,-9.659302109,-11.22544806,-8.343966882,-3.131284202 -2266,P143I,-0.124723237,0.022631219,-0.06551781,-0.228083257,-2.005215035,-0.009572492,-0.063933646,-0.185512827,-0.061946442,0.043551648,0.001710789,0.001122164,-0.132157783,-0.088948189,-0.367218324,-1.822119698,-2.188310372,0.961765723,1.318747064,-8.517390579,-10.08056106,-11.37134324,-7.456979057,-5.98103772,-7.697031822,-5.676446916,-2.20098652 -2267,P143H,-0.01400415,-0.060021736,-0.065957663,-0.063149184,-0.652308892,-0.012056058,-0.022413492,-0.005594808,-0.013609597,-0.025324009,-0.094719462,-0.058919333,-0.072995992,-0.039095221,-0.087203147,-0.579309619,-0.725308165,1.234363111,1.625315763,-13.04623011,-13.3688552,-16.07421033,-10.91184659,-11.04256599,-13.83367247,-9.074199408,-5.571040707 -2268,P143K,-0.023671493,-0.011107724,-0.09688148,-1.622279905,-2.718579118,0.048967531,0.034438626,-0.081781611,0.023904781,-0.093722563,0.071507115,-0.090163611,-0.103599348,-1.401993487,-1.842566323,-2.162994091,-3.274164145,1.012579794,0.746354982,-11.46886972,-12.29676807,-14.53057054,-9.349727699,-9.556155525,-11.61112675,-7.934823852,-3.162355406 -2269,P143M,-0.028300197,0.019771131,0.028614414,-0.865263771,-2.50650652,-0.051351501,0.041746234,-0.098346627,-0.136148448,-0.017261789,0.05680405,0.012467398,0.04476143,-0.500198509,-1.230329032,-2.24673398,-2.76627906,1.681270468,1.345340835,-10.91956935,-12.4040781,-13.57858528,-9.827217285,-9.860710327,-8.92725576,-8.005466323,-2.086890233 -2270,P143L,-0.069901857,0.016946881,-0.019754515,-0.973330075,-1.965140669,0.032872637,-0.040426506,-0.099377207,-0.001331792,0.0120802,0.021813562,0.000767597,-0.040276626,-0.459567137,-1.487093013,-1.545065473,-2.385215864,1.835056517,1.561962605,-8.978137535,-11.87773618,-10.60471458,-7.919180016,-6.610610878,-7.87844603,-7.157352134,-1.754621274 -2271,P143N,-0.047994887,0.022793876,-0.02139908,-0.757630274,-1.942733992,0.029940152,-0.029506526,-0.066483248,-0.054393304,0.006904405,0.038683347,-0.026017367,-0.016780792,-0.288605328,-1.22665522,-1.942084356,-1.943383627,1.33580458,1.341437604,-12.22861652,-12.28358269,-15.29183935,-11.12916464,-10.50826353,-11.93023238,-9.513602443,-5.964658021 -2272,P143Q,-0.033764503,0.067979289,0.012350669,0.012693448,-1.269922254,0.02447694,0.028745075,-0.096274081,-0.051621792,0.053803524,0.082155053,0.049616893,-0.024915556,0.086557229,-0.061170333,-1.119379945,-1.420464562,0.453999266,1.324218126,-11.51428711,-12.45492176,-13.73444318,-10.09584335,-9.589359459,-11.69686783,-8.094200721,-4.14833374 -2273,P143S,-0.054796433,0.001417655,-0.014364027,-0.021803705,-1.696646089,0.009052072,-0.03571065,-0.073882215,-0.025774752,0.018070564,-0.015235254,-0.004460602,-0.024267451,0.036599037,-0.080206446,-1.610957117,-1.782335061,0.514476698,1.306907684,-7.742215562,-6.923545563,-9.644116714,-7.500043251,-6.992863266,-7.650509018,-7.631680548,-4.731246773 -2274,P143R,-0.04389502,0.01665216,-0.156711473,-1.443419754,-2.376351269,0.072213813,-0.010187705,-0.077602334,-0.021634924,-0.044471102,0.077775422,-0.088323197,-0.225099749,-1.280221379,-1.606618128,-1.776104543,-2.976597994,3.573738718,2.713546761,-10.99257254,-12.00351657,-13.73030212,-8.860979362,-8.760707184,-11.60735744,-7.628152818,-3.512597695 -2275,P143T,-0.017624823,0.057412229,0.010783477,0.001014245,-1.151452176,0.067474994,0.010002722,-0.045252367,0.00367954,0.066514693,0.048309764,0.043518243,-0.021951289,0.052567164,-0.050538675,-1.020670119,-1.282234232,0.581681915,1.340959376,-6.191726691,-6.04389904,-8.428460068,-5.909918976,-4.912681175,-5.663674194,-6.507101136,-2.31663867 -2276,P143W,-0.000664814,0.045913963,-0.613228645,-2.109361463,-3.021949433,0.033801729,0.069815221,-0.071144848,0.011684896,-0.034468899,0.126296824,-0.307006702,-0.919450587,-1.477685999,-2.741036926,-2.700567891,-3.343330975,1.543601527,0.850944875,-12.94510947,-12.75166636,-16.18462139,-11.21995959,-11.28570535,-13.28359467,-9.033611025,-5.269048819 -2277,P143V,-0.013427064,0.047426811,-0.025616377,-0.041868353,-1.539005603,0.025029683,0.015545994,-0.042400121,-0.022800205,-0.000169072,0.095022694,-0.033473897,-0.017758857,-0.038131522,-0.045605183,-1.560934099,-1.517077106,0.9227773,1.334189947,-7.760243381,-8.611276825,-10.87627431,-6.51744294,-5.406311516,-7.389911316,-5.808696795,-2.55664857 -2278,P143Y,-0.083510742,0.037057951,-0.071059861,-2.117514864,-2.758068812,0.0720154,-0.061421784,-0.105599699,-0.018278327,0.008108923,0.066006978,-0.04153321,-0.100586512,-1.486991221,-2.748038506,-2.165805068,-3.350332555,1.075878807,0.732854611,-12.89427005,-14.68626721,-16.16381075,-9.996887955,-10.09441668,-13.52996767,-7.762556547,-4.307385026 -2279,K144A,-0.006117771,-0.080593749,0.002331417,-0.009388397,-0.072388927,0.048290677,0.01476768,-0.027003221,0.010292264,-0.079850648,-0.08133685,-0.040938787,0.045601621,-0.027326684,0.00854989,-0.062482442,-0.082295411,1.356455985,2.37120265,0.302930457,0.275363205,-0.39577549,0.77296669,0.512806564,0.349291313,-2.209876447,0.954975532 -2280,K144C,-0.045242494,-0.068711581,-0.01396067,-0.033098357,-0.171929079,0.105578579,0.0000777,-0.090562688,-0.012907638,-0.072455965,-0.064967197,-0.022636732,-0.005284607,0.003015482,-0.069212195,-0.145069305,-0.198788852,1.250716872,2.12455322,-5.767952528,-5.110060425,-6.708175957,-5.978851822,-5.527362381,-5.515312058,-7.908438113,-5.478130544 -2281,K144E,0.001336261,-0.025060049,-0.002331254,-0.015830223,-0.022203867,0.003069423,0.041253265,-0.038580744,-0.016028753,-0.057707469,0.007587371,-0.019412481,0.014749974,-0.007947353,-0.023713093,-0.058864047,0.014456313,1.3962876,2.5036407,0.633493449,0.385567764,0.397957436,1.121579803,0.950045395,0.312316849,-2.600582312,0.870753971 -2282,K144D,-0.076503938,-0.081352289,-0.013722559,-0.064692552,-0.055729847,0.092765002,-0.02683749,-0.126170386,0.004756833,-0.110774891,-0.051929687,-0.06430178,0.036856663,-0.024633686,-0.104751417,-0.092386937,-0.019072757,1.36285572,2.295180681,-1.837801918,-1.791420197,-3.141954613,-0.318335037,-2.514191109,-1.423108635,-4.601068156,0.722602588 -2283,K144G,-0.016011456,-0.042885912,-0.006566879,-0.017222104,-0.020137482,0.023783593,-0.003259748,-0.028763163,0.013208295,-0.070958004,-0.01481382,-0.046260129,0.033126371,-0.018489068,-0.015955139,-0.04639569,0.006120727,1.31870905,2.431119397,-2.564994164,-2.284029167,-4.277086945,-1.913944374,-2.125563316,-2.224347015,-4.411702013,-0.527993782 -2284,K144F,0.048200585,0.009135824,0.042906682,-0.00583436,-0.074061544,0.014287564,0.057242353,0.039158816,0.079987625,-0.038672889,0.056944536,-0.054156318,0.139969682,-0.04219065,0.030521931,-0.098231745,-0.049891343,1.372849976,2.309139269,-5.085984941,-3.649625038,-6.715675591,-5.442262283,-4.948583572,-4.673778221,-6.913211511,-4.194719319 -2285,K144I,-0.014477304,0.003957895,-0.0095023,0.065604517,0.047126188,-0.025531258,0.015414862,-0.044369469,-0.052958175,0.040586383,-0.032670594,0.031405969,-0.050410569,0.147072839,-0.015863806,0.001833794,0.092418581,1.137271404,2.68373177,-3.847411601,-2.089312737,-4.874347984,-3.896762314,-4.432372147,-3.944262825,-6.416659948,-3.406380153 -2286,K144H,-0.031426318,-0.007453538,0.048767436,0.031028704,-0.009511754,0.098168112,0.019629486,-0.082482121,-0.032233212,0.034617614,-0.04952469,0.047023901,0.05051097,0.048289639,0.013767769,0.023878149,-0.042901656,1.124699656,2.582810921,-3.294593239,-2.369472504,-4.827764923,-3.256610931,-2.966116379,-3.053001457,-4.91540279,-2.635765889 -2287,K144M,-0.030677691,-0.052012224,-0.036494798,-0.046657784,-0.076435888,0.033177189,0.009756144,-0.071111525,-0.000786915,-0.101875003,-0.002149445,-0.100676494,0.027686898,-0.064160289,-0.029155279,-0.121309766,-0.031562009,1.494608538,2.298426105,-3.756495451,-2.791544212,-4.906698021,-3.52389724,-4.072224609,-3.488113174,-5.781763948,-3.579595325 -2288,K144L,-0.028383135,-0.068444093,-0.014159005,-0.023360785,-0.083766349,0.032343275,-0.005900178,-0.050866091,0.027364958,-0.051738965,-0.085149221,-0.023832264,-0.004485745,-0.002449079,-0.044272491,-0.075705196,-0.091827501,1.351470762,2.355316543,-3.180989313,-2.005607544,-4.206407318,-3.396513557,-3.336563362,-2.959854782,-5.463245106,-2.810241832 -2289,K144N,-0.030653458,-0.019735421,0.019137653,-0.018144852,-0.004878996,0.036265724,-0.009139058,-0.052167858,0.025501781,-0.009102675,-0.030368166,-0.002556184,0.04083149,0.007129481,-0.043419184,0.033103296,-0.042861287,1.146717002,2.694846918,-2.689599971,-2.497229416,-3.908333771,-2.267078102,-2.420422813,-2.354935753,-4.6225795,-1.253847636 -2290,K144Q,-0.015007248,-0.044765932,0.006803765,0.003477131,-0.012246845,0.057304697,0.011979674,-0.04199417,0.080263362,-0.069327262,-0.020204602,-0.000288323,0.013895853,-0.037923441,0.044877703,-0.033730776,0.009237086,1.277769363,2.454005964,1.194169879,1.315619934,1.224047997,1.108029457,1.537407219,0.785744789,-2.057751389,-0.102232791 -2291,K144P,-0.056837282,-0.103395044,-0.021428383,-0.039765344,-0.127841549,0.083365502,-0.035530576,-0.078143987,0.012711667,-0.063020679,-0.143769409,-0.051519502,0.008662737,-0.022853326,-0.056677361,-0.10377577,-0.151907327,1.502683455,2.427753997,-1.937269453,-1.436102142,-3.022859886,-1.289556236,-2.156744995,-1.781084007,-3.631408579,-0.510029683 -2292,K144S,-0.049289785,-0.08164013,0.011166372,-0.025468378,-0.054032556,0.064306298,-0.013642209,-0.08493736,0.013471642,-0.060438321,-0.102841938,-0.009987288,0.032320032,-0.021798819,-0.029137936,-0.043647131,-0.06441798,1.299251671,2.391722178,-0.382830165,-0.408854431,-0.339947189,-0.557738159,0.000766876,-0.608377922,-2.560178641,-0.358870387 -2293,K144R,-0.057966532,-0.112444244,-0.010584129,-0.035538135,-0.081195363,0.055999597,-0.038576068,-0.077356995,0.000115359,-0.091841547,-0.133046941,-0.052569125,0.031400868,-0.026521241,-0.044555029,-0.061275555,-0.10111517,1.200807553,2.262246452,-1.984859116,-1.566212204,-3.576941986,-1.574171654,-1.569263084,-1.63770665,-4.540416486,-1.07919313 -2294,K144T,-0.031893651,-0.078255985,0.018076231,-0.034641512,-0.074526532,0.045888701,-0.003147274,-0.060640027,0.005554747,-0.039030326,-0.117481643,0.010727647,0.025424814,0.011412463,-0.080695486,-0.022870337,-0.126182727,1.266983826,2.593799908,-1.595598286,-1.0801063,-1.929799835,-1.068138802,-2.1464048,-1.753541695,-3.531766616,-0.593603585 -2295,K144W,-0.017560163,-0.05158539,0.019913603,-0.002688137,-0.261537109,0.067386068,0.035637531,-0.070757856,0.051007998,-0.071731501,-0.031439279,-0.025920223,0.065747428,0.007343121,-0.012719395,-0.240250809,-0.282823408,1.28184705,1.934994197,-6.73066387,-5.641495476,-8.407188049,-6.820401855,-6.437429665,-6.346804306,-8.812428334,-7.855780111 -2296,K144V,0.034359195,-0.024476558,0.004586651,-0.016167922,-0.046394863,-0.004641254,0.05299052,0.01572787,0.057371519,-0.065426236,0.01647312,-0.040672076,0.049845378,-0.029807823,-0.00252802,-0.10147134,0.008681615,1.237718668,2.192071787,-2.539870451,-1.394438072,-3.418200874,-2.235449615,-2.862221313,-2.789042381,-4.97990092,-2.456621448 -2297,K144Y,-0.048801954,-0.065310692,0.012981718,-0.084173709,-0.174016484,0.074583821,-0.016132627,-0.08147128,0.014396317,-0.065327515,-0.065293868,-0.053411956,0.079375392,-0.065886651,-0.102460767,-0.126025356,-0.222007612,1.528177275,2.337570839,-5.643091803,-3.905824646,-7.693876381,-5.947505211,-5.370201523,-5.298051254,-7.23729785,-4.716147851 -2298,E145A,0.022845756,0.00631522,-0.014641312,-0.021954263,-0.027764073,-0.072845512,0.00301391,0.042677602,0.011867588,0.004105509,0.008524931,-0.056584034,0.02730141,-0.032374579,-0.011533946,-0.041875898,-0.013652248,1.468686135,2.631213339,1.743392242,1.219158829,1.93155175,2.178545311,0.803248238,2.584457085,-1.793517546,1.799167409 -2299,E145C,0.043467187,0.082231826,0.018240006,0.019472262,-0.054622107,-0.027692176,0.037572702,0.049361671,-0.03699381,0.118358578,0.046105073,-0.017136698,0.053616709,0.014530995,0.024413529,-0.092053977,-0.017190236,1.416405485,2.403274077,-5.778317261,-6.809432465,-5.853200623,-5.216282837,-6.457572273,-4.555098106,-7.688842471,-3.908355492 -2300,E145D,-0.011863652,0.030829768,0.023021358,-0.032399874,-0.053888558,-0.011271006,-0.031593849,0.007866546,-0.146170616,0.00697162,0.054687915,0.038113804,0.007928912,-0.004163785,-0.060635963,-0.081843617,-0.025933498,1.250022999,2.324347277,-3.329968303,-3.516924591,-4.392891373,-2.730646118,-3.527546135,-2.481833298,-5.350867019,-1.552260371 -2301,E145G,0.000818953,0.031151365,0.018635137,0.013202008,-0.009259429,-0.103087892,-0.01312609,0.014763995,0.025350836,0.035416637,0.026886093,0.008385102,0.028885171,0.005678827,0.020725188,-0.02882837,0.010309512,1.318549401,2.548144504,2.634117546,2.34168972,2.476275658,3.353485672,2.092528259,2.906608421,-1.556127996,1.154514236 -2302,E145F,0.03877373,0.069160796,0.019534863,0.036830789,-0.010103721,-0.061507104,0.014220781,0.063326679,0.022808292,0.052346915,0.085974677,-0.02398782,0.063057546,0.020663625,0.052997952,-0.072582235,0.052374794,1.312338293,2.412514195,-5.493358243,-6.379035995,-5.167361389,-4.520440445,-6.93263578,-4.467317604,-6.845080586,-2.246614135 -2303,E145I,0.021632242,0.034570276,-0.016591138,0.011127513,-0.196790129,0.038924162,0.070113745,-0.026849262,-0.148262165,-0.025634284,0.094774836,-0.076697937,0.043515661,-0.019205137,0.041460162,-0.193206143,-0.200374114,1.202093781,1.946879852,-4.712768831,-5.146645027,-4.633297913,-4.058873802,-5.572827904,-4.152199509,-7.144536454,-2.409681867 -2304,E145H,-0.081839461,-0.015559262,-0.012826337,-0.0243495,-0.071933538,-0.04285923,-0.110413045,-0.053265877,-0.03775049,0.027355769,-0.058474293,0.017281234,-0.042933908,-0.005250541,-0.043448458,-0.031907606,-0.11195947,1.297238333,2.549696033,-5.29394483,-6.477287674,-4.781894409,-5.255828835,-4.916055519,-5.038657715,-6.108466924,-1.841764068 -2305,E145K,-0.076558844,0.005615403,0.024360251,0.032623615,-0.034367585,-0.045516646,-0.074693499,-0.078424188,-0.077175263,0.147030106,-0.1357993,0.090773337,-0.042052836,0.048846526,0.016400703,-0.003429131,-0.065306039,1.361033919,2.799517791,-0.338064066,0.078408905,-0.669888405,-0.762160133,-0.153487297,-0.183193398,-3.028864711,0.124197997 -2306,E145M,0.032224465,0.015993195,0.046906279,-0.005485568,0.002160508,-0.008474213,0.024539803,0.039909126,-0.05597384,0.012988382,0.018998008,-0.012795048,0.106607606,0.01731673,-0.028287865,-0.026224173,0.030545188,1.190436872,2.492016566,-4.606095792,-5.389888954,-4.216062058,-4.325534248,-4.827102936,-4.271890762,-6.428849548,-2.874728951 -2307,E145L,-0.017335511,0.006945561,0.000790482,-0.021533885,-0.185923179,-0.07039387,-0.029855599,-0.004815422,-0.024955127,0.032140685,-0.018249563,-0.014012877,0.01559384,0.005627558,-0.048695328,-0.148991867,-0.222854491,1.493747231,2.326430617,-4.650396411,-5.269429222,-4.976234077,-4.58054007,-4.460128212,-3.965650475,-6.532051257,-2.52470143 -2308,E145N,-0.056568786,-0.009446367,0.015387708,-0.02253726,-0.082234238,-0.034583653,-0.105021458,-0.008116114,-0.050152716,0.015861247,-0.034753981,0.02740289,0.003372525,-0.042587998,-0.002486521,-0.053768946,-0.11069953,1.272643205,2.332220377,-2.90443363,-3.57780265,-3.186611473,-3.046425804,-2.825981415,-1.885346809,-6.157731432,0.234787609 -2309,E145Q,0.014477441,0.022088366,0.047769373,0.028610389,-0.051717017,-0.100241434,-0.03239694,0.061351822,0.009325957,0.016754201,0.027422531,-0.004083413,0.099622159,-0.009399914,0.066620692,-0.044963812,-0.058470221,1.270198658,2.429479188,-0.98067986,-0.946041107,-1.281467972,-1.17690081,-0.380323746,-1.118665665,-4.348638757,-0.660509924 -2310,E145P,-0.015483134,0.028818318,0.001621454,-0.026806884,-0.365045508,-0.017538035,-0.040944601,0.009978333,-0.002220481,0.026975583,0.030661053,-0.025761432,0.02900434,-0.006848993,-0.046764775,-0.291053381,-0.439037635,1.019048146,1.703051022,-3.633864691,-4.916064903,-3.299061424,-3.222200508,-4.196377411,-2.535619209,-6.203360854,-1.76662898 -2311,E145S,0.015603817,0.009995098,0.020813252,-0.007909723,-0.019853986,-0.072531346,0.002118512,0.029089121,-0.02810294,0.052861026,-0.032870831,0.005595475,0.036031029,-0.022708867,0.006889422,-0.018305093,-0.021402878,1.489016835,2.794626567,-0.742267497,-1.805109505,-0.244460335,-0.446374527,-0.928086327,-0.287306793,-4.218926581,-0.310399684 -2312,E145R,0.007639279,-0.008101718,0.025245251,0.015498078,-0.086826265,-0.055318108,-0.007191362,0.022469919,0.002341216,0.049697989,-0.065901424,0.014269956,0.036220545,0.007358027,0.023638129,-0.058703062,-0.114949468,1.159687426,2.315883348,-2.366750713,-3.176674179,-2.712939896,-2.146143425,-2.013504623,-1.78449144,-5.172789439,0.147264091 -2313,E145T,-0.014741609,0.000174913,-0.02332578,-0.015505611,-0.100024051,-0.07175675,-0.061533878,0.032050661,-0.0119918,0.024140833,-0.023791007,-0.005827772,-0.040823787,-0.014919923,-0.016091299,-0.103480811,-0.096567291,1.39301399,2.288843354,-2.057515475,-2.967739624,-1.34069529,-1.935306236,-2.496219154,-1.547617073,-5.297373462,-0.152210339 -2314,E145W,-0.012279912,-0.002168963,0.031635458,-0.010807999,-0.182909331,-0.048243591,-0.00414354,-0.020416284,-0.000112062,0.052168492,-0.056506418,0.03562338,0.027647536,0.028229485,-0.049845483,-0.124774015,-0.241044646,1.306080109,2.198350787,-7.723893787,-8.40468222,-7.670265808,-7.175258827,-8.348087036,-7.021175041,-8.733595714,-5.269939067 -2315,E145V,0.002117856,-0.001501229,-0.015994641,-0.017126544,-0.058114107,-0.052030869,-0.022976708,0.027212419,0.024123673,-0.033175846,0.030173389,-0.065256655,0.033267374,-0.042400874,0.008147787,-0.096995268,-0.019232946,1.451035594,2.370000038,-1.508527324,-1.736321571,-1.459332428,-1.187650711,-2.327846581,-0.831485329,-4.480943757,-0.291165862 -2316,E145Y,0.039136678,0.021443648,0.039206544,-0.026655111,-0.131728189,-0.098739179,0.005006806,0.073266549,0.106351569,0.030952313,0.011934982,-0.03033284,0.108745927,-0.036317047,-0.016993174,-0.085792674,-0.177663703,1.343824961,2.330025806,-5.598873189,-6.617844658,-4.936351341,-5.11924324,-6.29916478,-5.021761925,-6.268809474,-1.20131469 -2317,L146A,-0.034015684,-0.012178268,-0.039606414,0.024280585,-1.532918971,0.07624879,-0.056910186,-0.011121181,0.071478781,-0.020740384,-0.003616151,-0.036997463,-0.042215365,0.0315296,0.01703157,-1.528424464,-1.537413477,0.602703507,1.314318895,-9.285173624,-9.940624847,-13.44735566,-5.978938667,-8.092017906,-8.966931038,-6.768816994,-2.888582564 -2318,L146C,-0.095799987,-0.000362203,-0.053614489,-0.434164286,-1.683595957,0.086013509,-0.152356841,-0.039243133,0.091061999,0.041149826,-0.041874232,0.015905065,-0.123134042,-0.068192134,-0.800136437,-1.726291024,-1.64090089,0.717562409,1.310414273,-10.21868455,-11.03765356,-13.80048784,-7.70036515,-9.09180471,-9.463111465,-8.110734371,-5.282824853 -2319,L146E,-0.016862116,-0.165975894,-1.21986184,-2.334064027,-2.67514971,0.012750069,-0.02464744,-0.009076792,0.086920451,0.044328799,-0.376280587,-1.078448789,-1.361274891,-2.012900152,-2.655227901,-2.565230885,-2.785068535,2.241326417,0.91437846,-12.8766624,-13.52648541,-16.29816574,-10.14197507,-11.78549281,-12.63119297,-10.12035764,-9.384185773 -2320,L146D,0.025355035,-1.397950819,-1.695217003,-2.059260921,-2.822895624,0.019997473,0.029049421,0.021660648,-0.006950625,-1.277565505,-1.518336133,-2.007476018,-1.382957987,-2.529746933,-1.588774908,-2.604956411,-3.040834837,0.344411359,-0.761082742,-13.40042178,-13.91537703,-17.46630545,-10.44640417,-12.12943458,-13.04458768,-10.12035764,-9.384185773 -2321,L146G,-0.058312487,-0.025574837,-0.051067283,-1.528366742,-2.258073028,0.033572789,-0.067787681,-0.048837293,0.080833231,-0.002205999,-0.048943675,-0.063055691,-0.039078874,-1.279300033,-1.777433451,-2.532206298,-1.983939758,0.794235456,0.729943097,-13.39802791,-14.04920962,-17.39055538,-10.1732344,-12.44954675,-12.92759339,-10.05899746,-9.054010444 -2322,L146F,-0.065970032,0.01890785,-0.092772345,-0.040227033,-0.118583427,-0.03242857,-0.148123025,0.016182961,0.018552074,0.036243687,0.001572012,-0.066744833,-0.118799857,-0.104341355,0.02388729,-0.090847525,-0.146319328,1.482664884,2.390179978,-3.538987567,-4.526194229,-5.00133741,-2.008054482,-3.450893478,-2.708458237,-4.053957397,-1.460972022 -2323,L146I,-0.033802792,-0.028658413,0.016936866,-0.043869964,-0.366678145,0.081841919,-0.029765598,-0.037839986,0.278964219,0.057756836,-0.115073662,0.034503156,-0.000629424,-0.082274613,-0.005465314,-0.101368149,-0.631988141,1.365435683,2.278024303,-5.414389583,-7.610069427,-6.047276482,-4.49085981,-4.372623062,-4.551119133,-5.016967098,-0.285261651 -2324,L146H,-0.022100333,-0.029496453,-0.542275262,-1.85043568,-2.870012064,0.099523757,-0.027946117,-0.016254548,0.050633342,-0.016846399,-0.042146507,-0.333822509,-0.750728015,-1.577236408,-2.123634951,-2.673635185,-3.066388942,1.662824201,0.864297087,-11.55926144,-12.21933997,-14.5518184,-9.100822281,-10.35627026,-11.56805628,-10.12035764,-9.384185773 -2325,L146K,-0.035675036,-0.938289933,-2.074359593,-2.52644914,-2.628974197,0.112475725,-0.005464304,-0.065885767,0.138027915,-0.599350722,-1.277229143,-2.077449262,-2.071269924,-2.298690181,-2.754208099,-2.37389966,-2.884048733,0.521770104,-0.492694696,-12.48295839,-13.48456676,-15.4292485,-9.839793343,-11.16048743,-12.50069592,-10.12035764,-9.384185773 -2326,L146M,-0.13054608,-0.02725167,-0.093790518,-0.159891116,-0.136688725,0.02572644,-0.15458479,-0.106507369,-0.07616268,-0.043048221,-0.011455119,-0.144276263,-0.043304772,-0.107644104,-0.212138127,-0.135317188,-0.138060261,1.487255086,2.265296799,-4.970610904,-6.93948941,-5.136935257,-3.775506607,-4.645992104,-4.355131142,-5.646593116,-2.959458489 -2327,L146N,-0.048626606,0.027940094,-1.139823056,-2.318061439,-2.571101493,0.072335759,-0.001589381,-0.09566383,0.260282006,0.041962569,0.013917619,-0.791952774,-1.487693338,-2.243642615,-2.392480263,-2.318852093,-2.823350893,1.706674007,0.634807573,-11.55906459,-13.12404513,-13.79113685,-8.801671089,-10.30998032,-11.76848954,-8.961731592,-6.190365436 -2328,L146Q,-0.040662958,-0.041412686,-0.088883041,-0.782644261,-1.880102708,0.031166042,-0.021382519,-0.059943397,0.044881013,-0.07424534,-0.008580032,-0.176087711,-0.00167837,-0.397328631,-1.167959891,-2.177974156,-1.582231259,1.590987158,1.324879616,-10.36511972,-11.25468963,-12.63250996,-8.33674614,-9.006149391,-10.59550349,-8.429290832,-6.190365569 -2329,L146P,-0.056003599,-1.035718776,-1.976450598,-2.218807875,-3.379138187,0.04566176,-0.057969233,-0.054037964,0.096628229,-0.835802699,-1.235634852,-2.061220048,-1.891681147,-2.118268931,-2.319346818,-2.846690924,-3.91158545,0.368269364,-0.581711185,-12.37640949,-13.02205361,-16.56278421,-9.019304909,-11.18262725,-12.09527749,-9.19881765,-6.656388847 -2330,L146S,-0.06944122,-0.057805539,-1.415366165,-2.025867845,-2.745330081,0.079292052,-0.053679787,-0.085202653,0.098424322,-0.013868869,-0.101742208,-1.257461942,-1.573270388,-1.846679647,-2.205056042,-2.751192899,-2.739467263,2.515883397,1.10419167,-11.89824601,-12.72011503,-15.36214629,-8.827651711,-10.91869865,-11.66261837,-8.657114141,-6.045910606 -2331,L146R,-0.043560151,-1.194805012,-2.174264603,-2.354320129,-3.408390178,0.034947364,-0.058388322,-0.02873198,0.076177064,-1.088294476,-1.301315547,-2.22474517,-2.123784036,-2.078009304,-2.630630953,-2.755278774,-4.061501582,0.185175308,-0.680099031,-12.52922387,-13.03829427,-15.92097142,-9.993565903,-11.13436214,-12.55892561,-10.12035764,-9.384185773 -2332,L146T,-0.079174973,-0.006270625,-0.088972772,-1.066424827,-2.590170917,0.061118061,-0.062686115,-0.09566383,-0.008730118,-0.047631847,0.035090597,-0.103463707,-0.074481836,-0.631877504,-1.500972149,-2.349304112,-2.831037722,1.675682113,1.280096763,-10.0039412,-11.30785107,-13.44700188,-7.184416245,-8.678493317,-9.401943512,-7.285420493,-2.709396702 -2333,L146W,-0.077790712,-0.014155393,-0.070337283,-0.056477677,-2.146566175,-0.037764442,-0.085874894,-0.069706529,0.065356599,0.030424403,-0.058735189,-0.046919936,-0.09375463,0.01010614,-0.123061493,-1.568310161,-2.724822188,0.606928577,1.312592777,-7.33054118,-8.213073227,-10.80822818,-5.336289886,-6.307485695,-5.987628914,-6.582509977,-4.255336582 -2334,L146V,-0.043334429,-0.017956725,-0.078163187,-0.059673077,-0.156148555,0.002177064,-0.096575796,0.009906938,0.001952812,-0.0412396,0.005326151,-0.07049134,-0.085835033,-0.056386773,-0.062959381,-0.157170161,-0.155126949,1.482721905,2.239707977,-4.417830127,-6.229835602,-5.18535743,-2.135071175,-4.063368736,-4.475517693,-3.748030633,0.473506039 -2335,L146Y,-0.106303734,-0.074100141,-0.103564794,-0.074514093,-2.179368697,0.027281917,-0.159495989,-0.053111479,0.147011457,-0.033423573,-0.114776708,-0.098383169,-0.108746419,-0.026711983,-0.122316203,-1.680069295,-2.678668098,0.229493018,1.298430085,-7.680214233,-8.520546555,-10.58918765,-5.760621719,-6.965394066,-6.565321175,-6.578878693,-4.295425403 -2336,T147A,0.022062627,0.011389082,-0.010877535,-0.037556241,-1.387123398,0.017455101,0.055586451,-0.011461197,-0.019409335,-0.038278711,0.061056874,-0.069506412,0.047751343,-0.059105944,-0.016006537,-1.399782544,-1.374464251,0.754414086,1.331212557,-7.667339949,-6.604745415,-7.809783325,-8.900242683,-7.590012428,-7.431915894,-5.668000225,-2.258778971 -2337,T147C,0.038408812,-0.071621238,-0.03330638,-0.026731487,-0.308931309,0.009069435,0.027030176,0.049787447,-0.059343736,-0.097282741,-0.045959735,-0.077734839,0.011122079,-0.06850722,0.015044247,-0.28005605,-0.337806568,1.617178365,2.167237634,-12.62910189,-11.64320908,-12.7559272,-13.86768423,-12.08303527,-12.79565366,-10.41234147,-7.632187008 -2338,T147E,0.082365632,0.036530605,-0.026065613,-0.02011953,-0.607522664,0.041221138,0.104538594,0.060192669,-0.030326121,0.003195778,0.069865432,-0.096585245,0.04445402,-0.075453734,0.035214674,-0.568999503,-0.646045825,1.693560615,1.946044848,-9.734872635,-7.394343208,-7.679792152,-12.37199245,-11.48108213,-9.747153229,-7.198864222,-1.835617294 -2339,T147D,0.090647072,-0.002851638,-0.014560061,0.023919816,-0.909715515,0.076219948,0.137959369,0.043334774,-0.048461132,-0.029252546,0.023549271,-0.062427207,0.033307086,-0.0541024,0.101942032,-0.841483357,-0.977947673,0.99741864,1.43980217,-10.12408034,-9.283466576,-8.565405701,-12.17729882,-10.87243678,-9.721793823,-5.957548871,-1.921370892 -2340,T147G,0.02756663,0.011423099,0.00387799,-0.017565204,-0.336406679,0.027825601,0.044602592,0.010530667,0.02597774,-0.020075564,0.042921761,-0.044944569,0.052700548,-0.054218974,0.019088567,-0.344158716,-0.328654642,1.493917872,1.978015035,-8.392482777,-8.065321075,-7.210821907,-9.883424942,-8.858687683,-7.944158279,-6.126722202,-3.577675564 -2341,T147F,0.004985754,-0.059418506,-0.238903318,-1.704516287,-2.976655135,-0.001604902,0.045828717,-0.03585721,-0.014846855,-0.108802128,-0.010034884,-0.232926354,-0.244880282,-1.558735777,-1.850296796,-3.043545443,-2.909764827,1.291544744,0.77133782,-13.0486452,-11.87626946,-13.73661357,-16.29012637,-11.90033024,-11.43988638,-8.951110965,-6.099940475 -2342,T147I,0.070851232,0.019368274,0.032542448,0.006371238,-1.282457123,0.026742172,0.113550247,0.028152216,-0.04843592,-0.000648761,0.039385308,-0.024102044,0.08918694,-0.041968241,0.054710717,-1.062207976,-1.502706269,0.834881747,1.367458187,-11.37532434,-11.65940349,-11.77472894,-11.7380573,-11.47842925,-10.2260027,-9.361592344,-5.859069174 -2343,T147H,-0.022954948,-0.032115741,-0.055724518,-0.076693398,-1.292782142,0.089525634,0.032493844,-0.078403739,-0.032644024,-0.00479925,-0.059432232,-0.052569169,-0.058879867,-0.083738746,-0.06964805,-1.200500238,-1.385064046,0.970922935,1.373864053,-12.00539479,-11.795002,-12.12862101,-12.7717579,-11.39212447,-11.93946858,-7.917691062,-3.428759661 -2344,T147K,-0.046906224,-0.033257449,-0.055360768,-0.070045941,-0.501617593,0.078192462,0.019628974,-0.113441422,-0.0000801,-0.047788552,-0.018726345,-0.121651196,0.010929661,-0.084515437,-0.055576444,-0.493784444,-0.509450742,1.702181029,1.992870018,-11.71117919,-11.44621854,-13.72228281,-12.25580257,-9.982599548,-11.14899247,-7.110757453,-2.900490068 -2345,T147M,0.034932628,0.038274469,0.02025315,0.015128206,-0.314493285,0.024504613,0.084025878,-0.014160622,-0.044782406,-0.039434512,0.11598345,-0.044453791,0.08496009,-0.047215279,0.077471691,-0.323032402,-0.305954168,1.021326574,1.661118937,-9.26300276,-9.731393074,-9.440511238,-9.684614571,-9.230287392,-8.228207527,-7.343513146,-3.825057316 -2346,T147L,-0.017113803,0.014193304,-0.018917854,-0.01216079,-1.710683524,0.030979958,0.024882067,-0.059109673,-0.049916004,0.013444981,0.014941626,-0.043432969,0.005597262,-0.025622002,0.001300422,-1.573302796,-1.848064251,0.584183557,1.311353098,-12.88251127,-13.20701052,-14.39724349,-13.18123598,-13.13496415,-10.4921022,-9.720364342,-6.657958814 -2347,T147N,-0.038856954,-0.087203464,-0.043146294,-0.057624507,-0.119655975,0.051518822,-0.030319695,-0.047394213,0.018634618,-0.072463634,-0.101943293,-0.093209145,0.006916557,-0.081754716,-0.033494297,-0.109720839,-0.12959111,1.554629113,2.398005756,-6.042720021,-6.414056778,-5.114996964,-7.758409164,-5.018322853,-5.907814346,-5.764438228,-0.193845046 -2348,T147Q,0.049848489,-0.064887079,-0.006934806,-0.026956711,-0.223975582,0.056022228,0.082244629,0.017452349,0.006748488,-0.036449277,-0.09332488,-0.034783121,0.020913509,-0.029826984,-0.024086438,-0.141638347,-0.306312817,1.364063412,2.208153016,-9.635149107,-8.835056831,-9.019253609,-10.2383288,-10.51477368,-9.568332611,-5.359546412,-1.408534912 -2349,T147P,-0.002512085,-0.038981717,-0.012788897,-1.30489685,-2.288112346,0.059525181,0.025272633,-0.030296803,-0.039177797,-0.035082581,-0.042880853,-0.06491985,0.039342056,-0.786656523,-1.823137176,-2.131193898,-2.445030793,1.920090641,1.380818631,-13.16452117,-12.26979005,-13.9565993,-13.67329617,-13.13581473,-12.78710557,-9.292108657,-5.448707295 -2350,T147S,0.021301805,-0.005765296,0.010263309,-0.032975752,-0.098120435,-0.002349005,0.036401396,0.006202213,0.003624683,-0.036191008,0.024660416,-0.030810098,0.051336716,-0.0467495,-0.019202003,-0.103939182,-0.092301687,1.417804283,2.340412478,-7.468601903,-7.192710915,-6.892370529,-8.909827095,-7.185879974,-7.162221001,-6.672827462,-3.944272064 -2351,T147R,0.037036407,0.019985377,0.019748768,-0.003629809,-0.122255423,0.145202149,0.087494768,-0.013421954,-0.099623224,0.018774986,0.021195767,-0.047824899,0.087322435,-0.050615138,0.04335552,-0.161346192,-0.083164653,1.629188205,2.365289872,-10.84258707,-10.94889198,-11.72583983,-9.769808487,-9.800727448,-11.96766761,-6.577469245,-2.207437122 -2352,T147W,0.014383552,-0.001359176,-0.008024587,-0.893420022,-2.021586879,0.030176719,0.042105385,-0.013338281,-0.030263125,-0.058050398,0.055332047,-0.071507866,0.055458693,-0.514089079,-1.272750965,-1.87461456,-2.168559198,1.787464926,1.449327755,-13.96691795,-13.02773247,-14.85883616,-15.0155601,-13.23193417,-13.70052685,-9.283797723,-6.099940578 -2353,T147V,0.072394674,0.058004098,-0.001758824,-0.029396438,-0.097500002,-0.000505498,0.091685169,0.053104179,-0.056811356,-0.021290375,0.13729857,-0.096363315,0.092845668,-0.059741442,0.000948566,-0.154209305,-0.040790698,1.425296623,2.215574258,-10.1901212,-10.3810152,-10.45105201,-9.946382339,-10.22518117,-9.946975304,-8.756306696,-5.263357834 -2354,T147Y,-0.019430118,-0.034379109,0.009364239,-1.598052652,-2.680316153,0.062267874,0.026428243,-0.065288479,-0.031025482,-0.040684114,-0.028074104,-0.049917476,0.068645953,-1.422858356,-1.773246947,-2.583775144,-2.776857161,0.622004561,0.709792114,-14.90103684,-13.80006189,-15.17759801,-17.60993013,-13.42868655,-14.48890765,-10.12983299,-7.15000833 -2355,A148C,0.001644196,-0.002224891,-0.05808538,0.005528764,-0.154317563,0.017589066,0.006515057,-0.003226665,0.016128025,0.010538252,-0.014988034,-0.092135609,-0.02403515,-0.036644692,0.047702219,-0.091848011,-0.216787114,1.462228225,2.377521386,-6.681457358,-6.161983978,-6.971356865,-7.38091674,-5.801538078,-7.091491127,-7.888532184,-6.325314993 -2356,A148E,0.0288149,0.029431551,-0.0790964,-0.001271977,0.024932066,0.00027529,-0.010665199,0.068294999,0.084247633,-0.006363376,0.065226477,-0.084475779,-0.073717021,-0.049774439,0.047230485,-0.057088846,0.106952977,1.415097418,2.441672406,-1.659040453,-1.763940895,-1.382456917,-2.190363571,-0.602351685,-2.356089195,-3.766807434,-1.085094486 -2357,A148D,-0.03426742,-0.000798701,-0.014351462,-0.008885485,-0.013729766,-0.011685064,-0.067733818,-0.000801021,0.092041782,0.018704847,-0.020302249,-0.010116199,-0.018586724,-0.007687123,-0.010083846,-0.024493481,-0.00296605,1.237023233,2.517427644,-1.774264165,-1.990384323,-1.663711395,-1.800460587,-1.169771034,-2.246993485,-4.012036294,-1.486957009 -2358,A148G,0.033317532,0.015772027,-0.018914038,-0.012160497,-0.016463353,0.000937439,0.02479992,0.041835144,0.052060125,-0.012909009,0.044453062,-0.082076356,0.044248281,-0.021801378,-0.002519616,-0.063288497,0.030361792,1.339784948,2.420667763,-2.871208112,-2.694453781,-2.894620697,-2.913121948,-2.687377182,-3.166466949,-4.146690507,-2.349109237 -2359,A148F,0.095295463,-0.049373701,0.003777629,0.002475958,-0.031785314,0.069537373,0.056005761,0.134585165,0.045076019,-0.08527966,-0.013467742,-0.101047341,0.108602599,-0.047828324,0.052780239,-0.061469181,-0.002101447,1.333538799,2.44493706,-6.91025022,-5.62188427,-7.185521698,-8.247621376,-5.747433022,-7.748790733,-7.570707088,-5.757002846 -2360,A148I,0.061226822,0.035919322,-0.037801538,0.095323611,0.019962406,0.182397643,0.054101554,0.068352089,-0.073272386,0.072767756,-0.000929112,-0.078855077,0.003252002,0.021437295,0.169209926,0.055313439,-0.015388628,1.259491033,2.893017684,-6.083708322,-5.547587723,-6.207755402,-6.327977898,-4.855540756,-7.479679832,-7.029212641,-5.311291291 -2361,A148H,0.047705551,0.018955911,-0.020074345,0.03410161,-0.002692202,0.012621841,0.03143757,0.063973532,0.053151119,-0.015341282,0.053253104,-0.041827197,0.001678508,-0.030146851,0.098350071,-0.036758658,0.031374255,1.270784864,2.459244756,-3.736685789,-3.036162926,-4.153887299,-4.081775177,-2.980743317,-4.430860229,-4.534694789,-3.231483226 -2362,A148K,0.005032661,0.047761797,0.016127241,-0.038354341,0.03095493,0.058522425,0.003800514,0.006264808,0.048260101,0.030428303,0.065095291,-0.004903119,0.037157601,-0.04934697,-0.027361711,0.052547474,0.009362386,1.12299802,2.676988626,-2.238199545,-2.071065842,-2.57423922,-3.281260521,-0.622791718,-2.641640427,-3.609042791,-1.286113865 -2363,A148M,0.136325088,-0.047523381,-0.005670045,-0.084710624,0.033247698,-0.12731969,0.106028778,0.166621397,-0.232973229,-0.090576,-0.004470762,-0.202124189,0.190784099,-0.052708872,-0.116712376,-0.091284358,0.157779753,1.360739959,2.268562279,-5.380625565,-5.116868408,-5.454628639,-6.054601097,-4.368098282,-5.908931396,-6.541269375,-4.498290021 -2364,A148L,0.027296894,0.029859424,0.010759302,0.050459807,0.047229992,0.024906584,-0.00182183,0.056415617,0.068215124,0.054789046,0.004929801,-0.012046607,0.03356521,0.027391367,0.073528246,0.027262911,0.067197073,1.339338372,2.847961086,-4.790198767,-4.205386505,-5.262026917,-5.245268135,-3.469557289,-5.76875499,-5.217574661,-3.382377551 -2365,A148N,0.008472485,-0.0092706,-0.015659933,0.071364457,-0.021430817,0.025021054,-0.000344803,0.017289772,0.042522971,0.021274363,-0.039815563,-0.015813765,-0.015506101,0.085178034,0.05755088,-0.000203889,-0.042657744,1.320165006,2.677285894,-2.989942674,-2.680794739,-3.110477608,-3.747995728,-2.103064224,-3.307381073,-4.831246384,-2.185656255 -2366,A148Q,-0.011222939,0.026698921,-0.032164215,0.026740219,-0.032812593,0.005295184,-0.035682211,0.013236334,-0.012347107,0.018140804,0.035257038,-0.051949875,-0.012378555,-0.008998987,0.062479425,-0.066096798,0.000471613,1.324961646,2.402815643,-1.976998178,-1.467542244,-2.018750351,-2.785982346,-0.94172773,-2.67098822,-3.846641902,-1.067410795 -2367,A148P,0.015720608,0.021313853,-0.026915419,0.006047457,-1.381794876,0.054266301,0.019659568,0.011781647,0.03050882,0.002240727,0.040386979,-0.057372286,0.003541448,-0.013512756,0.02560767,-1.416467434,-1.347122318,0.604097544,1.319491312,-5.487982811,-4.680855011,-5.014827553,-6.391617073,-4.928239288,-6.42437513,-6.891084549,-4.482013792 -2368,A148S,0.024507357,-0.028076865,-0.014147682,0.01260874,-0.047102173,-0.016079443,0.001503791,0.047510922,0.041785972,-0.003936943,-0.052216786,-0.049767285,0.021471921,-0.016028352,0.041245831,-0.051366209,-0.042838136,1.272351541,2.38649509,-1.860157939,-1.620459145,-1.91235936,-2.681492973,-1.1387024,-1.947775818,-2.678527456,-1.842491553 -2369,A148R,0.056977379,0.012031408,0.00509983,0.0177334,0.019409463,0.005014298,0.04299103,0.070963728,-0.026528983,-0.005931158,0.029993973,-0.06449213,0.07469179,-0.025674942,0.061141741,-0.038595071,0.077413997,1.331553658,2.489237444,-1.538461917,-1.090633202,-2.005216446,-1.496868355,-1.117170029,-1.982421555,-3.025063717,-0.776887336 -2370,A148T,0.032737141,-0.020103024,-0.020914089,-0.004093654,-0.040016796,0.014325465,0.027633235,0.037841046,0.053397299,-0.006777759,-0.033428288,-0.071073467,0.02924529,-0.021286575,0.013099268,-0.020720102,-0.059313489,1.278865205,2.381581446,-2.09942028,-1.936599136,-2.13792115,-2.356985512,-1.241464745,-2.824130859,-3.291314823,-2.200589491 -2371,A148W,0.10885759,0.076481021,0.028562625,0.030399474,-0.039664242,0.016883384,0.12680037,0.090914809,0.050402028,0.016604056,0.136357985,-0.018903024,0.076028274,-0.007527522,0.068326469,-0.1208961,0.041567616,1.374599104,2.294895244,-6.504989421,-5.489832855,-6.790646561,-7.228506317,-5.799230782,-7.216730591,-7.403794182,-5.431339991 -2372,A148V,0.05349313,-0.008821716,-0.044994693,-0.011312445,0.003099286,0.058461331,0.04827026,0.058716,0.007038365,-0.05089029,0.033246859,-0.096467144,0.006477759,-0.047258803,0.024633914,-0.072213103,0.078411674,1.37892799,2.371480017,-4.364630952,-3.877420654,-4.545561493,-4.858937019,-3.408264175,-5.13297142,-5.300264652,-3.87726509 -2373,A148Y,-0.017991726,-0.080737102,-0.098418833,-0.00284377,-0.126288959,0.056337441,-0.042099011,0.00611556,0.139031045,-0.029850715,-0.131623489,-0.063297139,-0.133540527,0.018695359,-0.024382899,-0.08897595,-0.163601968,1.336557061,2.30175345,-7.081957329,-5.790491272,-7.40847879,-8.332373131,-5.808967094,-8.069476357,-7.693808579,-5.85464797 -2374,F149A,0.040286465,0.060909383,-0.016501785,-0.033655895,-0.582402575,0.004158413,0.027562535,0.053010394,0.002018804,-0.012020147,0.133838913,0.006837811,-0.03984138,0.01999157,-0.08730336,-0.430388054,-0.734417096,0.783446995,1.492646231,-10.32655865,-8.020104248,-12.62823712,-13.61807543,-8.830995232,-8.535381218,-4.733122938,-1.519623259 -2375,F149C,0.059576734,0.094869827,0.011257842,0.022014554,-1.616961674,0.094867855,0.06525333,0.053900137,0.017271264,-0.026734301,0.216473954,0.036872501,-0.014356817,0.027727401,0.016301706,-1.535603302,-1.698320045,0.649342845,1.31668358,-10.96814646,-9.097073029,-12.38646564,-11.76214357,-11.37881529,-10.21623479,-7.124339075,-3.365949771 -2376,F149E,0.002007039,0.100715267,0.011505175,-0.020404046,-1.318017717,-0.022971041,0.063545656,-0.059531578,0.022476537,-0.038484626,0.239915159,0.031961601,-0.008951251,-0.003285342,-0.037522749,-1.164231735,-1.471803698,0.740227027,1.348584401,-12.04548338,-9.609107071,-13.79513521,-14.16214963,-9.853826378,-12.80719863,-6.556943344,-2.382055233 -2377,F149D,0.007066676,0.044556634,-0.002155516,-0.006561474,-1.722814002,0.048427541,0.069722747,-0.055589396,0.044351911,-0.001424958,0.090538225,0.014626422,-0.018937453,0.05407933,-0.067202278,-1.55433228,-1.891295723,0.800161766,1.325193733,-13.45469605,-10.57104749,-15.11081541,-16.21398959,-12.19730969,-13.18031808,-6.550279201,-3.52725783 -2378,F149G,0.053034823,0.099121435,0.03770568,-0.547502585,-1.767180068,0.055481448,0.069452643,0.036617002,-0.026048857,-0.020379766,0.218622635,0.032775096,0.042636264,-0.174326874,-0.920678296,-1.83891709,-1.695443046,1.104288071,1.326902868,-13.12006158,-11.31522638,-13.94873898,-15.6440715,-11.75544701,-12.93682403,-6.647444075,-3.819986786 -2379,F149I,-0.000160379,0.083384299,0.024293341,0.020608355,-0.067300137,0.021107062,0.020140911,-0.020461668,-0.044551123,-0.004759439,0.171528036,0.051608954,-0.003022272,0.071175591,-0.029958882,-0.040222255,-0.094378018,1.29224426,2.637785846,-9.864096999,-7.527008522,-11.36589468,-11.49187062,-8.799048767,-10.1366624,-5.636649129,-2.821442962 -2380,F149H,0.039914892,0.063269795,0.026776955,-0.005875142,-0.565551312,0.060617624,0.047965501,0.031864283,0.0333586,-0.022989453,0.149529043,0.0338525,0.019701409,-0.017772798,0.006022514,-0.480569647,-0.650532977,1.316234439,1.758297938,-10.05514,-9.670787354,-11.05214809,-10.71742863,-9.917519173,-8.91781678,-6.397315547,-3.787704944 -2381,F149K,-0.032924389,0.056922601,-0.039732013,-0.027358441,-1.31821425,0.006102804,0.091445207,-0.157293985,0.034573498,-0.073169034,0.187014236,-0.044619877,-0.034844148,0.00149909,-0.056215971,-1.360067052,-1.276361447,0.768398305,1.335675711,-12.82191288,-10.05416396,-14.53259662,-15.00312672,-12.18763982,-12.33203728,-6.085602987,-3.355713921 -2382,F149M,0.098619145,0.092031108,0.09320669,0.054909558,-0.010095765,-0.017257939,0.121460043,0.075778246,0.017887995,-0.048266539,0.232328755,0.068859519,0.11755386,0.065027388,0.044791727,-0.042547498,0.022355969,1.245298734,2.521548694,-8.597977412,-7.402101852,-10.51820609,-7.70014254,-9.020210724,-8.349225853,-6.05753849,-2.609377384 -2383,F149L,0.031110656,0.088662292,0.038625162,0.005882525,-0.262966181,0.002921481,0.067539493,-0.005318182,0.007627269,0.012389997,0.164934587,0.090663226,-0.013412903,0.037997477,-0.026232427,-0.201781351,-0.32415101,1.495444804,2.219955252,-6.984806213,-5.887959732,-8.16932563,-6.538271187,-6.598287506,-7.730187012,-4.301733502,-1.364094085 -2384,F149N,-0.035530906,0.096952001,0.046421682,-0.03676396,-1.70591085,0.035952536,0.015378863,-0.086440674,0.001623966,0.007943888,0.185960114,0.055679455,0.037163908,0.069249593,-0.142777512,-1.571662167,-1.840159532,0.499663658,1.30860262,-13.40351785,-10.85361479,-15.65903705,-14.94843861,-13.17108476,-12.38541405,-7.332437749,-4.634775901 -2385,F149Q,0.035587671,0.134240325,0.00973854,-0.019069881,-1.090552187,0.011499466,0.072528981,-0.00135364,-0.021115168,0.0000426,0.268438049,0.030281542,-0.010804463,0.004505474,-0.042645236,-0.644967547,-1.536136826,0.717539268,1.408916111,-12.86427143,-9.642229324,-14.19237731,-15.31577441,-11.83568346,-13.33529263,-5.995322775,-3.192284834 -2386,F149P,-0.000369375,-0.851965643,-1.979390965,-2.340609463,-3.196857481,0.057785031,-0.003312611,0.002573862,0.086561395,-0.615921449,-1.088009836,-1.898667622,-2.060114307,-2.084839961,-2.596378965,-2.744612939,-3.649102022,2.853548464,0.940414789,-15.89338192,-13.48252468,-18.03496117,-17.64867516,-15.51378389,-14.78696469,-10.21044336,-9.087452226 -2387,F149S,0.027881156,0.074545352,0.015578222,-0.002463083,-1.357072082,0.02949975,0.022319651,0.033442661,-0.028270099,-0.016346511,0.165437215,0.053527276,-0.022370832,0.043077329,-0.048003494,-1.185682257,-1.528461907,0.770383588,1.347393147,-11.10537738,-8.752261269,-13.46157404,-12.66738418,-11.02219539,-9.623472031,-6.048349197,-2.637172638 -2388,F149R,0.059749899,0.128760614,0.070710869,0.021153243,-1.359686127,0.040158889,0.072772624,0.046727174,-0.010827302,-0.008139344,0.265660571,0.071548657,0.069873081,0.053551967,-0.011245481,-1.28173653,-1.437635724,0.561401425,1.323358187,-12.06967206,-8.664966179,-12.68169221,-15.31616233,-12.47617533,-11.20936423,-6.333587406,-1.402821157 -2389,F149T,0.001885976,0.079642171,0.025121984,-0.016112233,-0.633217506,0.013003385,-0.004325725,0.008097677,-0.04428184,0.004936383,0.154347959,0.086255882,-0.036011915,0.028957785,-0.06118225,-0.462922963,-0.803512049,0.773657927,1.476857317,-11.29191496,-8.188310486,-14.13101454,-14.11273743,-11.52987959,-8.497632759,-5.674976907,-1.259765276 -2390,F149W,0.06461485,0.109235302,0.034816719,0.018352704,0.106530647,-0.027555102,0.054669803,0.074559897,0.040985026,-0.045089955,0.263560558,0.02369736,0.045936078,-0.00828885,0.044994257,-0.000490258,0.213551552,1.1989643,2.538207767,-5.671315671,-5.280903954,-5.410339088,-4.612119034,-5.85590226,-7.197314018,-4.596994301,-1.541866897 -2391,F149V,-0.019289679,0.07274538,0.026812948,-0.045842744,-0.434599858,0.006302969,0.015632935,-0.054212293,-0.04718747,-0.030341485,0.175832244,0.082483339,-0.028857444,0.02851307,-0.120198557,-0.317187056,-0.55201266,0.936003614,1.647982485,-9.942329851,-7.447230835,-12.22129475,-11.89783201,-8.510326088,-9.634965576,-6.237694734,-1.930620254 -2392,F149Y,0.044560399,0.067977586,0.03486357,0.002598509,0.016628017,-0.070360452,0.074560576,0.014560222,-0.022265618,-0.016635298,0.15259047,0.017400775,0.052326365,-0.017019532,0.02221655,0.018287434,0.0149686,1.120864082,2.612443991,-2.734921671,-2.394275696,-2.887829697,-2.43709314,-3.458864502,-2.496545319,-2.132023946,-0.703397778 -2393,L150A,-0.023584839,0.001733995,0.027900283,0.02703957,-0.212270694,0.052746188,-0.031796765,-0.015372912,0.03156621,-0.018118727,0.021586716,0.039731819,0.016068747,0.046827816,0.007251323,-0.167394494,-0.257146893,1.203696634,2.047301484,-8.144220461,-8.71687999,-8.895113777,-7.504944878,-5.44997477,-10.15418889,-4.693826241,-0.821271685 -2394,L150C,-0.002671534,0.00739807,0.021204176,0.020484061,-0.476126661,0.013315117,0.013900976,-0.019244043,0.032001343,0.01337604,0.0014201,0.058969542,-0.016561191,0.067601579,-0.026633457,-0.350712967,-0.601540355,0.564801113,1.457683362,-11.18288795,-12.37227635,-12.47233546,-10.29001392,-10.07531344,-10.70450057,-5.686090948,-2.208912991 -2395,L150E,-0.088371667,-0.093591989,-1.219768392,-2.190217996,-2.878848421,0.090897126,-0.077625975,-0.099117359,0.106920165,0.059886385,-0.247070362,-0.784071574,-1.65546521,-1.657008097,-2.723427894,-2.844002719,-2.913694122,2.139324044,1.036520662,-14.81219449,-14.91566449,-15.96125401,-14.81466446,-13.16431033,-15.20507917,-9.030679088,-7.110701665 -2396,L150D,-0.148466565,-0.409866169,-1.311951202,-1.787175184,-2.440127655,0.0647391,-0.154956903,-0.141976227,0.025955715,-0.134429694,-0.685302643,-1.428510164,-1.195392239,-1.749553305,-1.824797063,-2.497215233,-2.383040076,3.285344165,1.737945696,-16.20151136,-15.98421342,-17.80841623,-15.97809306,-14.20976674,-17.02706735,-9.964609497,-9.414628367 -2397,L150G,-0.037781783,0.053545522,0.026022831,-0.238188437,-1.756685573,0.07305187,-0.023828773,-0.051734793,0.054184264,-0.008015019,0.115106063,0.004452308,0.047593353,-0.017776003,-0.458600871,-1.849582597,-1.663788548,0.866081733,1.311837357,-13.51054475,-13.66037441,-14.50035725,-13.2428195,-11.10401696,-15.04515563,-7.128239393,-4.23882271 -2398,L150F,-0.06644371,0.063259295,0.003095361,0.031013823,-0.14995674,0.096091874,-0.005511754,-0.127375666,0.04734172,0.088658128,0.037860461,0.029646777,-0.023456056,0.167080067,-0.105052421,-0.065851469,-0.23406201,1.543610422,3.106887046,-4.923029857,-3.937935684,-7.327540894,-4.555425735,-4.754539436,-4.039707535,-4.322044208,-1.474033409 -2399,L150I,-0.035805746,0.005854104,0.026517584,0.012605325,-0.107601528,-0.063500446,-0.052608076,-0.019003415,0.242143943,-0.006801819,0.018510026,0.067094497,-0.01405933,0.0276528,-0.00244215,-0.069644458,-0.145558598,1.377796773,2.500889127,-5.735022328,-4.868571037,-7.175873985,-6.208252174,-4.025719948,-6.396694496,-4.466925568,-0.985457731 -2400,L150H,0.010326974,-0.0000984,0.013194442,-0.68746154,-2.50799963,0.051910324,0.032624475,-0.011970528,0.148082516,-0.006530045,0.006333318,-0.026236669,0.052625553,-0.279213223,-1.095709857,-1.947073041,-3.068926219,1.346444244,1.341517906,-14.98430627,-16.49960552,-16.56049813,-13.94391112,-13.26248879,-14.65502776,-9.170114389,-7.110701665 -2401,L150K,-0.181997301,-0.841734404,-1.973387984,-2.446042147,-2.676445598,0.047433311,-0.191696332,-0.17229827,0.068956485,-0.427227976,-1.256240832,-2.13148291,-1.815293058,-2.054586043,-2.837498251,-2.501217975,-2.851673221,0.750088025,-0.35224161,-14.66709831,-14.92348183,-16.29221439,-14.73180854,-12.6625778,-14.725409,-9.232420879,-7.110701665 -2402,L150M,0.092587069,0.179335212,0.112077513,0.091372157,0.091401533,-0.049605821,0.084471135,0.100703002,0.229535578,0.091185106,0.267485317,0.056329446,0.167825579,0.080349082,0.102395232,-0.014499317,0.197302383,1.100080585,2.476287868,-3.116546719,-3.179685211,-2.843832947,-4.543422722,-2.636067726,-2.379724991,-2.88821799,-0.940447249 -2403,L150N,-0.017720253,-0.014225482,-0.014509528,-0.030351361,-2.256755267,0.060836282,0.015712016,-0.051152522,0.218055761,-0.011782754,-0.016668209,-0.030387333,0.001368278,0.072838474,-0.133541195,-1.867483815,-2.646026718,0.496138171,1.297985678,-14.18204029,-15.00603425,-14.4262442,-13.98019204,-12.33575796,-15.16197301,-8.138807374,-5.674645896 -2404,L150Q,-0.07553734,-0.062725079,0.013701327,-0.227173863,-1.552336112,-0.003981943,-0.063550274,-0.087524406,-0.003756323,-0.059548428,-0.065901729,-0.031409603,0.058812257,-0.031108888,-0.423238838,-1.473891804,-1.630780419,0.817772387,1.328862368,-14.08945655,-14.81496547,-14.91342899,-14.50094481,-12.18209534,-14.03584814,-9.229588848,-7.110701665 -2405,L150P,-0.065382715,-0.591879758,-1.832835433,-2.193421863,-3.152874322,0.132956534,-0.05167147,-0.079093959,0.066893855,-0.363832692,-0.819926824,-1.777221602,-1.888449263,-1.960609762,-2.426233963,-2.786158466,-3.519590178,2.961349662,1.195106381,-13.95135334,-14.78890691,-16.01038294,-14.10014202,-10.77193285,-14.08540197,-8.052557913,-5.453076044 -2406,L150S,-0.046776632,0.006580284,0.016289713,0.023886551,-1.733232711,0.075543037,-0.037579605,-0.055973659,0.044787858,0.006563462,0.006597106,0.008949517,0.023629909,0.050579541,-0.00280644,-1.554219363,-1.912246059,0.528071421,1.309947401,-12.07809325,-12.83869256,-12.12662861,-11.19378027,-9.692075134,-14.5392897,-6.961312436,-4.069379053 -2407,L150R,-0.053265798,-1.021739354,-2.230770936,-2.461390042,-3.202388142,0.114226462,-0.020167505,-0.08636409,0.098114714,-0.85882605,-1.184652657,-2.459076155,-2.002465716,-1.96304998,-2.959730103,-2.652719961,-3.752056322,0.242857089,-0.605414424,-14.66356464,-15.05870915,-15.77528696,-14.96910018,-12.94443404,-14.57029287,-9.0262718,-7.110701665 -2408,L150T,-0.049834562,0.010273896,0.037321355,0.018731574,-0.568561937,0.058967847,-0.049840529,-0.049828594,0.08289463,0.021523827,-0.000976036,0.061320526,0.013322183,0.048060425,-0.010597277,-0.432077064,-0.705046809,1.112025771,1.65511589,-10.16093898,-10.46579289,-11.99792701,-10.07658891,-7.478969467,-10.78541664,-5.826601027,-3.147321718 -2409,L150W,-0.058640561,0.018804504,-0.02076738,0.000173713,-1.612677789,0.061150674,-0.044170486,-0.073110636,0.126847726,-0.032218605,0.069827613,-0.011952403,-0.029582357,0.02182707,-0.021479644,-1.58580745,-1.639548128,0.540930195,1.309569983,-10.37916801,-12.61706778,-12.43342667,-8.607806931,-9.65004908,-8.587489601,-5.766095277,-2.782122702 -2410,L150V,-0.086111033,0.004775975,-0.004066034,-0.013784925,-0.092748906,-0.013150112,-0.075247764,-0.096974301,0.103177621,-0.010398032,0.019949982,0.046300801,-0.054432869,0.064870954,-0.092440803,-0.073030053,-0.112467759,1.242938643,2.373763752,-5.985536081,-5.131223442,-6.809540764,-6.163364365,-3.988440224,-7.83511161,-4.268977272,-1.717242375 -2411,L150Y,0.026452536,0.001174105,0.024649657,0.035319501,-0.668788279,-0.091565285,-0.022369983,0.075275055,0.126796022,-0.04677414,0.04912235,0.029006319,0.020292994,-0.000630487,0.071269488,-0.62515948,-0.712417077,1.12631369,1.550543118,-10.84543168,-11.993997,-13.3719113,-10.16871259,-9.384828171,-9.307709335,-6.616223794,-3.887668859 -2412,H151A,-0.046477108,0.021157649,-0.020395872,0.015322638,0.03070164,0.031942726,-0.002989353,-0.089964863,0.006604732,-0.016497253,0.058812551,-0.062303241,0.021511497,-0.050637469,0.081282745,-0.019153563,0.080556843,1.15077845,2.403569891,-1.585838867,-1.835880821,-1.11686821,-0.817658203,-2.43031926,-1.728467842,-3.496475538,0.844447922 -2413,H151C,-0.045538208,0.025167295,-0.054516723,-0.036545309,-0.143451535,0.042520052,-0.009179281,-0.081897134,-0.011888189,0.014139093,0.036195497,-0.071872483,-0.037160962,-0.062247834,-0.010842784,-0.132103218,-0.154799851,1.605452852,2.414478064,-4.563567526,-4.527917664,-4.41438118,-4.26418409,-4.752473061,-4.858881638,-5.1744613,-3.352667046 -2414,H151E,-0.047776822,0.006297255,-0.033884789,0.033886409,0.044633236,0.06700167,-0.03021653,-0.065337113,-0.045654487,-0.041028821,0.053623331,-0.082410489,0.014640911,-0.023319223,0.091092041,0.018220682,0.07104579,1.173169195,2.582666349,-2.24050645,-2.255801834,-1.697778114,-3.013594978,-2.762445465,-1.472911858,-3.212838432,0.345157791 -2415,H151D,-0.044039707,0.022865284,-0.065824241,0.008280047,-0.029224302,0.06492058,0.016005792,-0.104085206,0.068952473,-0.018023579,0.063754146,-0.078268978,-0.053379504,-0.005781877,0.02234197,-0.075783487,0.017334883,1.334714106,2.375770155,-3.470302002,-3.41700042,-2.496059975,-4.205064293,-4.34515802,-2.888227303,-3.396490071,0.049035716 -2416,H151G,-0.080441065,0.028835296,-0.039573646,0.017249979,0.029651278,0.044385369,-0.006707934,-0.154174195,-0.004901134,0.015216511,0.04245408,-0.055479394,-0.023667898,-0.018065403,0.052565361,0.0013677,0.057934856,1.230666477,2.641543675,-2.948444298,-3.067135582,-2.874492989,-3.137199028,-3.647219734,-2.016174156,-3.625289979,-1.20003284 -2417,H151F,-0.045549962,0.017724714,-0.086559009,-0.031241672,-0.018411069,0.052757941,0.006628898,-0.097728821,0.011482734,-0.046858364,0.082307791,-0.145880984,-0.027237033,-0.094208853,0.031725509,-0.098890761,0.062068624,1.399454659,2.284323753,-5.699448419,-5.044653404,-5.797788589,-6.27377948,-4.563595345,-6.817425278,-5.987863801,-4.276592733 -2418,H151I,-0.091118696,0.042732436,-0.004307714,0.054077597,0.007014468,-0.009626771,-0.040491866,-0.141745525,-0.001857362,0.006585955,0.078878916,-0.012686722,0.004071294,0.010000399,0.098154794,0.001941657,0.012087278,1.460651789,2.864537266,-3.177519615,-3.546555328,-3.824728447,-3.588412224,-2.858729332,-2.069172745,-3.86348977,-1.920640228 -2419,H151K,-0.115419731,0.020234528,-0.065171224,-0.005745355,0.007145897,-0.015184435,-0.062193873,-0.168645589,0.055915981,-0.055918003,0.096387058,-0.073744278,-0.056598169,-0.048055698,0.036564989,-0.028823178,0.043114972,1.380879553,2.572656279,0.01622829,-0.209568008,-0.305590096,-0.810663803,0.45093084,0.956032516,-1.999887147,0.796016994 -2420,H151M,-0.084675154,0.032402332,-0.03601272,-0.000894781,0.04515802,0.018803699,0.002492075,-0.171842383,-0.004921327,-0.0000778,0.064882464,-0.028905156,-0.043120284,-0.027030649,0.025241087,-0.003807361,0.0941234,1.245227119,2.512020517,-4.272683931,-4.512946747,-4.075936508,-4.390445129,-4.570787605,-3.813303665,-4.896618336,-2.977771011 -2421,H151L,-0.03714882,0.024070079,-0.018514441,0.023054959,-0.024805365,0.060781385,-0.007202656,-0.067094983,0.02129678,0.000404481,0.047735676,-0.045726634,0.008697752,-0.012015829,0.058125747,-0.030168044,-0.019442686,1.329506211,2.632417145,-1.846781851,-2.658192329,-1.532461014,-2.128407913,-1.854939163,-1.059908836,-2.757528375,-1.108467014 -2422,H151N,-0.04167483,0.111773845,-0.00887768,0.057593869,0.079552158,0.015522741,0.059770731,-0.143120391,-0.025132627,0.023678893,0.199868797,-0.013080232,-0.004675128,0.017106575,0.098081162,0.033374576,0.125729739,1.209489535,2.733143689,-2.263015172,-2.250972794,-2.489696518,-3.587867317,-2.049047302,-0.937491928,-3.480179374,-0.295191553 -2423,H151Q,0.008097306,0.049487545,-0.023534331,0.020552461,0.068242096,0.012247869,0.024699538,-0.008504926,-0.035589159,0.026356983,0.072618106,-0.035769896,-0.011298765,-0.012973296,0.054078217,0.027385939,0.109098253,1.203635836,2.578888789,0.001940097,0.125892868,0.062662415,-0.164153305,-0.235706337,0.221004845,-2.039955341,0.357678089 -2424,H151P,-0.108832139,-0.021637302,-0.052757775,-1.106333963,-2.286537924,0.074657818,-0.050747093,-0.166917185,-0.020200868,-0.016304524,-0.02697008,-0.069524175,-0.035991374,-0.838893923,-1.373774003,-2.011578778,-2.561497069,2.143913215,1.526947865,-5.068095193,-4.291822182,-5.608892792,-4.753143005,-6.059317398,-4.627300591,-5.164181419,-2.937473589 -2425,H151S,-0.038089448,0.026742527,-0.03233603,-0.009772832,0.010206805,-0.013619527,0.011139602,-0.087318497,-0.00040807,0.001291514,0.052193539,-0.042432608,-0.022239452,-0.028454668,0.008909005,-0.014489889,0.034903499,1.170104237,2.370551146,-2.427499944,-2.709459015,-2.572771545,-2.807108597,-2.464512917,-1.583647644,-3.764147701,-0.528210525 -2426,H151R,-0.031582805,0.013201901,-0.03382406,0.00759869,0.02308135,0.026862903,0.005308768,-0.068474378,-0.039748774,-0.01149753,0.037901331,-0.050839445,-0.016808675,-0.020141915,0.035339294,0.010763435,0.035399264,1.155493763,2.649198214,4.344642407,4.331341728,4.692338112,5.363595131,3.47327803,3.862659035,-0.198878904,2.545079743 -2427,H151T,-0.070903951,0.023371469,-0.045426524,0.028249188,0.016665056,0.019913848,-0.009841546,-0.131966355,0.028475753,-0.004828746,0.051571683,-0.056941548,-0.0339115,-0.017645631,0.074144006,-0.009570299,0.04290041,1.27048636,2.589348045,-2.731234155,-2.628215569,-2.418522293,-2.816511993,-3.382757095,-2.410163826,-3.317627615,-0.636017668 -2428,H151W,-0.103750802,0.020314651,-0.043713862,-0.002036515,-0.034528765,0.018080151,-0.066175233,-0.141326371,0.077846187,0.011673414,0.028955887,-0.050398819,-0.037028905,-0.023713847,0.019640817,-0.017600803,-0.051456726,1.299376244,2.559621862,-4.98897953,-4.91882827,-4.922684837,-5.326031517,-4.991850777,-4.785502251,-6.305067339,-4.257562887 -2429,H151V,-0.053295484,0.00728024,-0.041171397,0.009840624,0.001629947,0.0249825,-0.039419472,-0.067171495,0.024944843,-0.045989575,0.060550055,-0.08687916,0.004536367,-0.031761714,0.051442961,-0.052323575,0.055583469,1.304107946,2.425258235,-2.983877829,-3.352835579,-3.512310669,-2.634823601,-3.164674255,-2.254745041,-4.354236141,-1.409153789 -2430,H151Y,-0.085886227,0.019180636,-0.057377683,0.002261466,0.007816278,0.039328978,-0.029727089,-0.142045364,0.012390965,0.025417259,0.012944012,-0.059040362,-0.055715003,-0.015163941,0.019686873,-0.020771072,0.036403628,1.39417163,2.600260542,-5.068441486,-5.341093628,-5.749372528,-5.767723907,-3.978729904,-4.50528746,-5.564242998,-3.272516818 -2431,N152A,-0.011433482,-0.04994268,-0.022527537,0.010882838,-0.039471638,-0.043359589,-0.013351196,-0.009515767,0.011803313,-0.020344468,-0.079540892,0.007183927,-0.052239,0.014283019,0.007482656,-0.00504614,-0.073897135,1.543610422,3.106887046,0.768850725,0.395616913,-0.024943428,2.089611641,1.223895515,0.160072983,-2.133677534,1.565206209 -2432,N152C,0.015336402,-0.034951536,0.003714497,0.043710741,-0.154368375,-0.035345216,0.022171002,0.008501801,-0.003458027,-0.020414465,-0.049488606,0.040376736,-0.032947743,0.02746781,0.059953671,-0.099158801,-0.209577948,1.369541129,2.402694163,-3.849361131,-3.618948624,-4.719303406,-3.156860054,-3.477322762,-4.274370811,-6.157985573,-3.730506074 -2433,N152E,-0.033090503,-0.062174784,-0.014990674,-0.056213158,-0.011654539,-0.124114048,-0.034000033,-0.032180972,0.073786214,0.13939483,-0.263744397,0.099498188,-0.129479536,0.107105524,-0.219531839,0.035778282,-0.05908736,1.140601244,2.8972879,0.65273307,1.161050987,0.217034134,1.165320793,1.430872047,-0.71061261,-2.795009478,1.83743699 -2434,N152D,0.054758835,-0.021588859,-0.008413435,0.049488544,-0.030300908,-0.049508684,0.068661483,0.040856187,-0.038500776,0.042091356,-0.085269073,0.012942122,-0.029768991,0.054255315,0.044721772,-0.000282892,-0.060318924,1.246123487,2.69232746,0.168927968,0.495791855,-0.647542694,0.385477547,1.553880066,-0.942966934,-2.332322142,1.216213012 -2435,N152G,-0.027611339,-0.053810583,-0.033734201,-0.011688862,-0.066780817,-0.02528902,-0.015056561,-0.040166116,0.05281695,-0.018405658,-0.089215508,-0.008719329,-0.058749072,-0.017047863,-0.006329861,-0.041435449,-0.092126185,1.178655953,2.382238516,0.768372581,0.304195663,1.183138817,1.209042168,1.248031105,-0.102544846,-1.522460535,1.25857957 -2436,N152F,-0.069340403,-0.063699459,-0.020861878,-0.000530987,-0.108405949,-0.004646525,-0.074917873,-0.063762932,0.001342488,-0.043669828,-0.083729089,0.002588175,-0.044311931,-0.012031087,0.010969114,-0.090938665,-0.125873232,1.808125749,2.84446623,-2.806405893,-3.024840897,-3.307155266,-2.054990761,-2.186311089,-3.458731453,-4.474009247,-2.455259395 -2437,N152I,0.030775419,0.012550933,-0.020116009,0.029934289,-0.079239517,-0.013439395,0.030858986,0.030691852,0.006984069,0.020539744,0.004562121,-0.028855479,-0.011376539,0.012476103,0.047392474,-0.067062023,-0.091417011,1.382262972,2.480259362,-3.087599748,-3.114035133,-3.766665771,-1.978974243,-2.797951118,-3.780372475,-5.141970217,-2.588873713 -2438,N152H,0.045923381,-0.001280085,0.004123616,0.029810105,-0.024670175,-0.050381217,0.044559213,0.047287549,0.019882567,0.008278591,-0.010838761,0.010343187,-0.002095956,0.026832796,0.032787414,-0.007348808,-0.041991542,1.222447558,2.570798611,-1.030588254,-1.248663322,-1.69190377,-0.176034386,-0.277528732,-1.758811058,-3.288689088,-1.350892114 -2439,N152K,0.003158785,0.013774009,0.008786061,0.051147214,-0.009286897,-0.029543416,0.017465254,-0.011147685,0.010718234,0.042928201,-0.015380183,0.091377963,-0.073805842,0.08538343,0.016910997,0.02493349,-0.043507283,1.096146598,2.673427032,1.715353564,1.620443321,1.373712898,2.393211372,1.749741745,1.439658485,-0.214358098,1.170426945 -2440,N152M,0.044283533,-0.030662074,0.024355115,0.069174231,0.054737748,-0.03740111,0.050431671,0.038135395,0.144009991,-0.056073295,-0.005250852,0.024382131,0.024328098,0.032262127,0.106086335,0.026008329,0.083467167,1.043048399,2.559148394,-2.381776381,-2.493438545,-2.984979553,-1.085790207,-1.869370338,-3.475303261,-4.871930773,-1.957744891 -2441,N152L,0.013555494,-0.023193484,0.004188682,0.04564749,-0.023505812,-0.028525767,0.026038891,0.001072097,0.039961961,0.027063993,-0.07345096,0.060467945,-0.052090582,0.048321959,0.042973021,-0.019168137,-0.027843487,1.148125972,2.50576595,-1.35959268,-1.201248047,-2.26440416,0.038652626,-0.600534775,-2.770429047,-3.298788544,-0.828496942 -2442,N152Q,-0.042668194,-0.052723915,-0.024074885,0.023678824,-0.018047744,-0.027222355,-0.044720729,-0.040615658,0.084737964,-0.017646029,-0.087801801,0.036199114,-0.084348884,0.057817165,-0.010459518,-0.024098985,-0.011996503,1.121957387,2.500446185,1.468100661,2.15658979,1.116757072,2.12848365,1.243643631,0.69502916,-1.300696584,0.870261335 -2443,N152P,-0.017327549,-0.013641998,-0.028842046,-0.811814577,-2.12322271,0.031354983,0.026861332,-0.06151643,0.024250056,0.003780999,-0.031064995,-0.012119708,-0.045564384,-0.338492418,-1.285136736,-1.902535715,-2.343909704,1.466137834,1.363625619,-5.075810951,-5.29488269,-5.314871552,-4.264208733,-4.653109894,-5.851981888,-7.433329364,-6.615121461 -2444,N152S,0.020134507,-0.014112863,-0.013367666,0.027804474,-0.015036709,-0.013167468,0.049892985,-0.009623971,0.014690272,-0.013324997,-0.014900728,0.004751113,-0.031486444,0.013550214,0.042058733,-0.00953398,-0.020539437,1.099033345,2.603512733,1.931280203,1.220965279,1.990486961,2.690310287,2.143699333,1.610939156,-1.455224552,2.453123231 -2445,N152R,-0.003717772,-0.023367294,-0.018911358,0.026811125,0.021453871,-0.016292373,0.001525304,-0.008960847,-0.004586294,-0.013420142,-0.033314445,-0.000501654,-0.037321062,0.011024178,0.042598072,0.002115921,0.040791821,1.177533209,2.56891234,0.98794026,1.749844803,-0.038460495,2.021581047,1.561235016,-0.354499069,-2.544891917,1.229301023 -2446,N152T,-0.020735158,-0.023301345,-0.027087315,0.02854487,-0.035577057,-0.005014857,0.00903169,-0.050502006,-0.044922233,0.018373624,-0.064976314,0.004267882,-0.058442511,0.043157804,0.013931936,-0.032509479,-0.038644634,1.08978692,2.361076049,0.645357855,0.817036591,0.214108017,1.927652321,0.711049278,-0.443056931,-2.262719106,0.866706216 -2447,N152W,0.031493919,0.014761499,0.018358901,0.011484901,-0.079932065,-0.004126793,0.034248874,0.028738964,0.058657193,0.036962453,-0.007439455,-0.015728729,0.05244653,0.015170952,0.007798849,-0.067915757,-0.091948373,1.443425681,2.567130944,-3.225853453,-3.221827431,-3.720396935,-2.719429031,-2.519909088,-3.947704781,-5.071211027,-2.697781782 -2448,N152V,0.020876126,-0.038652517,-0.014410437,0.025214738,-0.04207795,-0.047828653,0.019783987,0.021968264,0.01614578,-0.035985595,-0.041319439,-0.018656864,-0.01016401,0.00841658,0.042012895,-0.064068489,-0.02008741,1.321427578,2.414619047,-2.657493413,-2.900746376,-3.221209946,-1.407447266,-2.271831673,-3.486231804,-4.745565372,-2.090942752 -2449,N152Y,0.001742513,-0.088085441,-0.039997519,-0.005133493,-0.111851337,-0.10883629,-0.020533333,0.024018359,0.056415895,-0.019722889,-0.156447992,-0.028904933,-0.051090104,0.013821521,-0.024088506,-0.070463882,-0.153238792,1.448219973,2.553812327,-4.094043797,-4.05106395,-4.739428261,-3.596618172,-3.612840286,-4.470268318,-6.50670837,-4.016306573 -2450,M153A,-0.000893157,-0.04853888,-0.024352192,-0.01493279,-0.068678108,0.043481003,0.015309604,-0.017095917,0.013322961,-0.092933626,-0.004144133,-0.074674269,0.025969886,-0.041686672,0.011821093,-0.120122695,-0.017233521,1.408112591,2.282057485,0.211929243,0.437196915,-0.090135231,0.575755928,-0.23217009,0.368998695,-1.746891411,-0.023798939 -2451,M153C,0.015455917,-0.074472176,-0.02530344,-0.003911755,-0.064515597,0.043405187,0.042595897,-0.011684064,0.01242164,-0.106103374,-0.042840977,-0.070646215,0.020039335,-0.031979185,0.024155676,-0.107687097,-0.021344096,1.568085565,2.44574677,-3.186487694,-2.263960205,-2.978620819,-2.346251724,-3.974744118,-4.368861603,-4.649066656,-2.505589322 -2452,M153E,-0.045572933,-0.075376562,-0.079731778,-0.057863318,-1.375037549,0.003339159,-0.012520982,-0.078624883,0.029383778,-0.086523533,-0.064229591,-0.105541976,-0.053921579,-0.070869834,-0.044856801,-1.299176098,-1.450899,0.973432174,1.361519153,-3.334168483,-3.409244881,-2.685111885,-2.718372231,-3.225838646,-4.632274773,-4.985266744,-2.71249938 -2453,M153D,-0.017972121,-0.120889881,-0.034838121,-1.314663933,-3.100132561,0.029438235,0.035049322,-0.070993564,0.015850057,-0.116235209,-0.125544553,-0.098828898,0.029152657,-1.020945203,-1.608382662,-2.755195666,-3.445069456,1.190455422,0.849291638,-5.097353734,-4.35689151,-4.215814331,-4.369893982,-6.259194763,-6.284974083,-6.465352212,-4.622148813 -2454,M153G,0.000116748,-0.070426135,-0.065525482,-0.039725743,-0.718774831,0.043237013,0.044669713,-0.044436217,0.061309338,-0.110951718,-0.029900551,-0.110731119,-0.020319845,-0.078920698,-0.000530787,-0.606176372,-0.831373289,1.406661204,1.700406313,-3.858278534,-3.313970657,-3.250262222,-3.220343544,-5.242351799,-4.264464447,-5.205583121,-2.46660317 -2455,M153F,0.031660399,-0.032419965,-0.044628696,-0.01831842,-0.201098063,0.004587052,0.078264185,-0.014943387,-0.040803012,-0.056522775,-0.008317155,-0.072701204,-0.016556187,-0.031902299,-0.004734541,-0.22128372,-0.180912406,1.453136502,2.105537494,-3.165231651,-3.659669022,-2.100636566,-1.939097076,-4.718081116,-3.408674477,-3.383627142,-0.879690432 -2456,M153I,-0.02279005,-0.069966051,-0.05886631,-0.025849928,-0.023306261,0.010288365,-0.000360241,-0.045219858,0.063780595,-0.075334311,-0.064597791,-0.085927384,-0.031805236,-0.023915812,-0.027784044,-0.032520619,-0.014091903,1.367357913,2.482879168,2.582267645,3.133136391,2.853251694,2.396836319,2.380410156,2.147703667,-1.27754249,1.526494021 -2457,M153H,-0.030460322,-0.064428352,-0.064770973,-0.051160113,-0.558468368,0.012488744,0.021857293,-0.082777937,0.013788284,-0.078836705,-0.050019998,-0.043050362,-0.086491583,-0.042793229,-0.059526997,-0.422596269,-0.694340467,1.266592186,1.714353044,-2.50647159,-0.550963654,-1.579324852,-1.241998947,-3.914439743,-5.245630753,-3.932681324,-0.624151115 -2458,M153K,0.000344509,-0.063911195,-0.046524016,-0.0000882,-1.354327293,0.016966521,0.060000798,-0.05931178,0.09397558,-0.076633007,-0.051189383,-0.054288727,-0.038759305,0.005664297,-0.005840665,-1.151225158,-1.557429427,0.885738327,1.362675293,-2.196114149,-0.935360588,-2.324760757,-1.56796151,-1.170633324,-4.981854568,-4.456458958,-0.435720121 -2459,M153L,0.021723107,-0.048140757,-0.042822708,-0.018348258,-0.047138285,-0.002502523,0.041060121,0.002386092,-0.027541573,-0.082715873,-0.013565641,-0.090437519,0.004792104,-0.036401733,-0.000294783,-0.091721595,-0.002554974,1.414371733,2.342971976,0.829538179,0.194063995,1.34887043,1.328326263,0.632747253,0.643682953,-2.055258549,2.355297257 -2460,M153N,-0.059078343,-0.100293009,-0.051161989,-0.046712507,-0.261438533,0.033236719,-0.030480956,-0.087675729,0.008509433,-0.101656436,-0.098929582,-0.036927277,-0.0653967,-0.03609188,-0.057333133,-0.245388017,-0.277489048,1.365314927,1.992304153,-0.776045782,0.470534561,-0.194879944,-0.589908401,-0.864574791,-2.701400337,-3.227705763,-0.625274569 -2461,M153Q,-0.001325717,-0.029950998,-0.040994471,0.00935391,-0.266883514,-0.003264083,0.022920625,-0.025572059,0.01615808,-0.030272778,-0.029629217,-0.044988329,-0.037000613,0.009399927,0.009307892,-0.241089409,-0.292677619,1.287016148,1.918296862,-1.568447328,-1.309676872,-1.711762474,-0.91107859,-0.772566887,-3.137151817,-3.494837563,-0.711963173 -2462,M153P,-0.045457594,-0.586410084,-1.689459473,-2.140285318,-2.742925642,0.067042502,0.012818969,-0.103734157,0.031219079,-0.365597408,-0.807222759,-1.671050111,-1.707868834,-2.11601345,-2.164557186,-2.737365795,-2.748485488,2.719060063,0.964372197,-5.153808401,-4.427905685,-5.026608253,-4.218106033,-6.119202263,-5.977219772,-6.629860404,-4.9961512 -2463,M153S,-0.003965683,-0.065935489,-0.039175656,-0.032096354,-0.113013127,0.020120345,0.036870812,-0.044802177,0.010467666,-0.097969296,-0.033901682,-0.0646766,-0.013674711,-0.031692198,-0.03250051,-0.117461293,-0.108564961,1.381479289,2.282366327,0.665545761,1.37475576,0.477734528,0.79950087,0.667361282,0.008376366,-2.363289409,-1.246606129 -2464,M153R,-0.031284621,-0.081091036,-0.052212341,-0.019139454,-1.312866025,0.040285937,0.01190677,-0.074476012,0.008397863,-0.084393713,-0.077788358,-0.073031365,-0.031393317,-0.037402243,-0.000876664,-1.125351386,-1.500380664,0.819115143,1.35732959,-3.684900705,-2.412994217,-3.313148895,-2.2555914,-3.479181602,-6.96358741,-4.428052127,-1.56020962 -2465,M153T,-0.003635446,-0.02968158,-0.033427214,-0.012525734,-0.079235997,0.042771225,0.019113598,-0.02638449,0.014957648,-0.068487111,0.009123952,-0.046797418,-0.020057009,-0.038788502,0.013737034,-0.123262159,-0.035209834,1.310114585,2.176296874,2.763943616,3.307744522,1.596822144,3.209587875,3.24173365,2.463829887,-0.947932556,-0.601092138 -2466,M153W,0.052658416,-0.067811038,-0.039329866,-0.006250692,-0.063727216,-0.003231626,0.072304735,0.033012096,-0.032091377,-0.124515225,-0.011106851,-0.115647163,0.036987432,-0.046808665,0.034307281,-0.143930724,0.016476293,1.534922162,2.301276998,-4.119347665,-2.434812645,-3.195022751,-2.828325371,-6.667254112,-5.471323448,-4.872816781,0.352898765 -2467,M153V,0.038254988,-0.066628092,-0.053315928,-0.011454779,-0.099218971,0.004970502,0.061975247,0.014534728,0.004978939,-0.108258414,-0.024997769,-0.088137456,-0.0184944,-0.058090226,0.035180668,-0.119767237,-0.078670704,1.462927073,2.306117247,-0.441975497,-0.425092422,-0.55407206,0.249824173,-1.239437469,-0.241099709,-2.719991605,-0.399499941 -2468,M153Y,0.007096401,-0.109894964,-0.063498895,-0.035205286,-1.035927336,0.010788699,0.05474992,-0.040557118,0.022754851,-0.146001897,-0.07378803,-0.093674653,-0.033323136,-0.044880358,-0.025530213,-0.76275478,-1.309099891,1.01803052,1.461709756,-4.124407455,-2.370607018,-2.921889221,-2.865353821,-5.803723366,-6.660463852,-4.632548685,-1.209919585 -2469,G154A,-0.069519442,-0.014709345,-0.025238107,-0.027580141,-1.237814556,-0.008313525,-0.053914673,-0.08512421,-0.012238959,0.015340573,-0.044759263,0.010110326,-0.06058654,0.000193681,-0.055353963,-0.98456598,-1.491063131,0.638010402,1.348888865,-6.699757701,-6.957807602,-6.17841069,-5.970554924,-6.608040634,-7.783974655,-7.070465463,-4.605993106 -2470,G154C,0.061699138,0.030642077,0.028610204,0.011641261,-1.748269181,0.072641281,0.083880532,0.039517743,-0.062367747,-0.006077608,0.067361761,-0.072748845,0.129969252,-0.068343878,0.0916264,-1.594745223,-1.901793138,0.897040265,1.330623285,-10.67275105,-10.64373613,-10.65413329,-9.998270927,-10.34248991,-11.725125,-10.23801718,-9.799455849 -2471,G154E,-0.030818934,-0.008143799,-0.012085322,-0.023197002,-0.123728146,-0.007812687,-0.013168187,-0.048469681,0.004011315,0.042298818,-0.058586416,-0.01001445,-0.014156193,0.038065057,-0.08445906,-0.091883591,-0.155572701,1.165170396,2.280433979,-6.282221382,-6.694281448,-6.303623459,-5.689124382,-6.076457695,-6.647619926,-7.424419403,-4.709355358 -2472,G154D,0.028673993,0.029727701,0.068894251,-0.003524526,-0.095326544,-0.018887621,0.009609884,0.047738101,0.062725365,0.029816371,0.02963903,0.004663378,0.133125123,-0.015973317,0.008924266,-0.078268969,-0.112384118,1.37018417,2.384313874,-4.050534453,-3.836264709,-4.300890121,-3.950629837,-3.816650764,-4.348236832,-4.203327512,-3.753263191 -2473,G154F,-0.126024532,-0.013778468,-0.019319133,-1.251859222,-2.091244835,0.04696338,-0.113748899,-0.138300165,0.067680395,0.009959789,-0.037516724,-0.010243382,-0.028394884,-0.758227892,-1.745490552,-2.337358148,-1.845131521,0.766748545,0.791042124,-10.98741669,-11.11834149,-10.31445856,-9.640827599,-10.55477,-13.3086858,-9.160623625,-7.332861106 -2474,G154I,-0.070364444,-0.004059375,-1.00798015,-2.035501323,-2.6520505,0.049201274,-0.017330149,-0.123398739,-0.189444115,-0.003153691,-0.004965058,-0.616295215,-1.399665084,-1.475491888,-2.595510758,-2.419893036,-2.884207963,2.383512447,1.318876642,-9.951609966,-10.59664423,-9.216638466,-8.706580681,-9.356460579,-11.88172587,-8.440169982,-5.879278424 -2475,G154H,-0.074773574,-0.045542659,-0.035083726,-0.032815073,-0.947665442,0.070243395,-0.046173209,-0.103373938,-0.025136331,0.001558412,-0.09264373,-0.069752551,-0.000414901,-0.027713879,-0.037916266,-0.65467167,-1.240659214,0.791563354,1.418985447,-7.105425505,-7.775099487,-7.016882172,-5.857788467,-6.436165871,-8.441191528,-7.172455042,-4.949104558 -2476,G154K,-0.058742891,0.02000366,-0.047415079,-0.056814204,-1.210318364,0.060809797,-0.008873522,-0.108612259,0.115463012,0.002450187,0.037557132,0.01440133,-0.109231488,0.000478917,-0.114107324,-1.05607221,-1.364564518,0.627515581,1.344324305,-5.645068147,-7.213880943,-4.736698204,-3.859962326,-6.100290604,-6.314508659,-6.373937817,-3.99748434 -2477,G154M,-0.039382187,0.115027162,0.045672846,-0.129232834,-2.123271348,-0.007799355,-0.054053493,-0.02471088,-0.019291095,0.140708572,0.089345752,0.046810281,0.04453541,0.030206096,-0.288671764,-1.699524887,-2.547017809,0.676398847,1.309820897,-10.52694867,-10.9298212,-10.24547222,-9.66501725,-9.640929291,-12.1535034,-9.138233118,-7.258488053 -2478,G154L,-0.056807799,0.026581221,0.000236938,-0.924058356,-1.828806882,0.038265838,-0.03520246,-0.078413138,-0.020302824,0.021261897,0.031900544,-0.086890767,0.087364642,-0.410328448,-1.437788264,-1.917926837,-1.739686926,1.615314093,1.389782603,-10.38756556,-10.76138893,-10.04543601,-9.787281265,-9.702346558,-11.64137503,-8.974184228,-6.70808671 -2479,G154N,0.037178341,0.057117967,0.043187729,-0.025664268,-0.235432728,0.043901896,0.009182891,0.06517379,-0.01424616,0.031377469,0.082858464,0.01828014,0.068095318,-0.022835815,-0.02849272,-0.126653285,-0.344212171,1.310563981,2.166794621,-5.402220216,-5.988703812,-4.882593849,-4.824374298,-5.358210495,-5.957218628,-6.313006516,-3.935840182 -2480,G154Q,-0.04880471,-0.011037841,-0.020479157,-0.06745567,-0.544538125,-0.000283455,-0.049663439,-0.04794598,-0.050430041,0.005700781,-0.027776463,-0.001955312,-0.039003002,-0.049079043,-0.085832297,-0.436592669,-0.65248358,1.318610701,1.763316696,-6.921066618,-7.915036606,-6.447889732,-5.799887093,-6.45945224,-7.983067421,-6.906009398,-4.878748221 -2481,G154P,-0.064134605,-0.017827902,-0.000721582,-1.128028785,-2.117260163,0.041383855,-0.029303851,-0.098965358,-0.006140951,-0.024102967,-0.011552837,-0.02477055,0.023327387,-0.645319526,-1.610738043,-1.817246556,-2.417273769,1.982267998,1.533326688,-8.871445451,-9.194732903,-8.282525299,-8.028753304,-8.425364532,-10.42585122,-8.238064256,-5.758034822 -2482,G154S,-0.02969886,0.040798173,0.011812035,-0.042061183,-0.952716773,0.027383653,-0.002065135,-0.057332585,0.060180358,0.024324271,0.057272074,-0.015292954,0.038917024,-0.040315154,-0.043807211,-0.737836222,-1.167597324,0.92163243,1.42205504,-6.86839415,-7.511909698,-6.646678291,-6.155345322,-6.501949554,-7.526087883,-6.557071094,-4.960697881 -2483,G154R,-0.019074487,-0.007897897,-0.004886792,-0.007619483,-1.558836255,0.024284791,0.006156223,-0.044305196,-0.034458644,0.002096008,-0.017891801,-0.029708201,0.019934618,0.033642562,-0.048881527,-1.407021784,-1.710650726,0.484834256,1.313717185,-6.502336949,-7.334469055,-6.513335403,-5.610071838,-5.935332291,-7.118476158,-6.657355317,-4.71675294 -2484,G154T,-0.062763307,-0.038722972,-0.034677977,-0.441178694,-1.714924849,0.020651929,-0.041550035,-0.083976579,-0.014438592,-0.019416766,-0.058029177,-0.075559823,0.006203869,-0.180812372,-0.701545016,-1.815040144,-1.614809553,1.255607206,1.346417981,-9.046001778,-9.161574768,-8.854704681,-8.343149666,-8.588078156,-10.28250162,-8.363718524,-6.3006191 -2485,G154W,-0.010926739,0.085994918,0.004156222,-1.457664516,-2.49126502,0.001744419,-0.025393846,0.003540368,0.019962204,0.024786896,0.147202939,-0.060702926,0.069015369,-1.21764196,-1.697687071,-2.151047724,-2.831482315,2.258185993,1.469591825,-10.85012607,-11.05415214,-10.27889148,-9.966582939,-10.69271499,-12.25828883,-9.659008957,-8.055785955 -2486,G154V,-0.171445638,-0.004294181,-0.106479471,-1.056478483,-1.669103351,0.015864218,-0.059711802,-0.283179474,-0.056097549,-0.028923085,0.020334724,-0.114167927,-0.098791014,-1.338920343,-0.774036622,-2.290054874,-1.048151827,1.034825432,0.754777847,-9.381235043,-9.859010956,-8.490148102,-8.257165894,-9.212892258,-11.08695801,-7.680342582,-4.759363595 -2487,G154Y,-0.031534836,-0.019082992,-0.033905889,-0.668787646,-2.325040513,0.045010975,-0.03696074,-0.026108932,0.051832508,-0.130889092,0.092723109,-0.109857227,0.04204545,-0.359414407,-0.978160884,-1.932204484,-2.717876541,1.546860767,1.373043656,-11.29682764,-11.10377769,-11.30934724,-10.19146714,-11.07056756,-12.80897854,-9.512232739,-7.853201445 -2488,D155A,0.003981678,-0.209671968,-1.448112198,-2.198496364,-2.933485535,-0.001336719,0.036747615,-0.02878426,-0.043573246,-0.133591914,-0.285752022,-1.475427345,-1.42079705,-2.092330415,-2.304662312,-3.142323272,-2.724647797,1.018820092,0.07359441,-9.207470869,-10.23106146,-9.923379257,-8.397717247,-10.11960451,-7.365591873,-6.909303913,-2.123813402 -2489,D155C,0.00015561,0.011852722,-1.071935327,-2.001723151,-3.234446418,-0.000157991,0.012187513,-0.011876294,-0.053970504,-0.02253401,0.046239454,-0.953059836,-1.190810818,-1.800411827,-2.203034475,-2.920985758,-3.547907077,2.273701507,1.020350433,-12.89184395,-14.16661003,-14.05482278,-12.16167262,-13.00244463,-11.07366968,-8.609268173,-2.630212658 -2490,D155E,0.036956696,0.013681047,0.053289349,-1.192240985,-1.954996729,-0.055472458,0.090595774,-0.016682382,-0.043791933,-0.084745682,0.112107776,-0.003351703,0.1099304,-0.676418237,-1.708063733,-1.633135365,-2.276858093,2.234129801,1.747693142,-8.345086324,-9.666049606,-7.976600433,-7.096618294,-9.189830063,-7.796333221,-8.45181249,-5.876338106 -2491,D155G,-0.006902624,-0.500754898,-1.709402491,-2.146929863,-2.942122497,-0.000832541,0.028717602,-0.04252285,-0.011127159,-0.392071916,-0.60943788,-1.652355846,-1.766449135,-1.967685713,-2.326174012,-2.690319635,-3.193925359,2.814822781,1.091849908,-10.86448262,-11.08599307,-11.25151942,-10.26652254,-11.75585658,-9.962521469,-8.082743788,-3.684269925 -2492,D155F,-0.091927257,-0.701017396,-1.902495431,-2.137297715,-2.888915262,-0.025752186,-0.050735004,-0.133119509,0.135611382,-0.538122617,-0.863912175,-2.269153578,-1.535837283,-2.116505569,-2.158089861,-2.538109496,-3.239721028,0.225128637,-0.516983346,-13.09466582,-16.37061021,-12.13025437,-12.39965823,-12.92583975,-11.64696652,-8.306901282,-2.175234237 -2493,D155I,-0.020107639,-0.257381828,-1.56686465,-2.021333282,-2.772950829,-0.156890409,-0.018263916,-0.021951361,-0.153384495,-0.18941422,-0.325349436,-1.480006943,-1.653722357,-2.026328939,-2.016337625,-2.447932866,-3.097968792,3.20779388,1.549624529,-11.56600494,-16.16951958,-11.99451606,-9.124165894,-11.3963289,-9.145494263,-6.134750105,-1.490672778 -2494,D155H,0.037100771,-0.590470596,-1.916107755,-2.301425038,-2.752012589,0.054235995,0.073644235,0.000557306,-0.020945121,-0.462183778,-0.718757414,-1.768715701,-2.063499808,-2.014007702,-2.588842373,-2.736641624,-2.767383553,2.897113103,1.084448845,-12.48529931,-13.93601223,-13.27072105,-11.1254513,-12.58130599,-11.51300599,-9.361902148,-5.509977217 -2495,D155K,0.053176643,-0.98425512,-2.154494734,-2.700921664,-3.063463586,-0.007847179,0.08541662,0.020936665,-0.00738334,-1.085416537,-0.883093703,-2.47695925,-1.832030217,-2.324311241,-3.077532086,-2.745915168,-3.381012003,0.442995593,-0.674153211,-13.1565329,-14.24897992,-14.37757285,-12.01937154,-13.81995053,-11.31678967,-10.09707451,-6.396893405 -2496,D155M,0.009467955,-0.367138789,-1.692735469,-2.301631767,-2.863143693,-0.063756395,0.061422785,-0.042486876,-0.003160518,-0.246392644,-0.487884933,-1.483033398,-1.902437539,-1.93244538,-2.670818153,-2.751989316,-2.97429807,2.829419601,1.200934606,-12.98772141,-17.06437338,-11.52828859,-12.67088252,-12.3828476,-11.29221494,-7.393728233,-2.332778638 -2497,D155L,-0.019981615,-0.806105347,-2.069682387,-2.164859561,-3.537996133,-0.029242232,0.003196626,-0.043159856,0.044183756,-0.65870638,-0.953504314,-2.176693185,-1.962671589,-2.082037123,-2.247681999,-3.047709095,-4.028283171,0.701386204,-0.479061443,-12.63340408,-17.16984715,-11.27880685,-11.74439623,-11.24773505,-11.7262351,-6.147999936,-0.566879436 -2498,D155N,-0.093440566,0.010202378,-0.005176472,-0.020706603,-2.020904202,0.026733311,-0.051644987,-0.135236145,0.056993016,0.005052681,0.015352074,0.069958075,-0.080311018,0.076478047,-0.117891253,-1.889193924,-2.15261448,0.673833079,1.301847403,-7.752150746,-8.90872184,-7.910207832,-6.096100044,-8.265003006,-7.580721008,-6.752407783,-4.172019344 -2499,D155Q,0.012764072,-0.065839765,-1.371767942,-2.345130853,-3.309732767,0.04653792,0.049808827,-0.024280683,-0.02622757,-0.057054971,-0.074624559,-1.094601826,-1.648934057,-2.544013808,-2.146247898,-2.965617735,-3.653847798,1.178927973,0.194664295,-12.81461205,-14.30453428,-13.43761433,-11.34158573,-14.14095853,-10.84836738,-9.204608973,-5.713355966 -2500,D155P,-0.010603617,-0.416758174,-1.780438571,-2.225378252,-2.876538378,0.007792343,0.035763314,-0.056970548,-0.027439132,-0.276614623,-0.556901724,-1.581949393,-1.978927748,-2.140505845,-2.310250658,-2.452965303,-3.300111452,2.63376026,0.956795314,-12.96530857,-14.17996324,-12.2905854,-12.38065716,-13.01403873,-12.96129832,-8.54062337,-3.799485948 -2501,D155S,0.015492007,0.018535481,-1.142645951,-2.036948482,-3.095545636,-0.006296648,0.049851541,-0.018867527,-0.032030609,-0.017832223,0.054903185,-0.836341429,-1.448950473,-1.976503086,-2.097393878,-2.824075745,-3.367015527,2.034027718,0.850867907,-12.0553607,-13.55211435,-12.30636098,-10.99822547,-12.98038394,-10.43971877,-8.999876688,-5.648331817 -2502,D155R,0.008025082,-1.067685035,-2.004968133,-2.203675495,-3.133164207,0.002900218,0.045609745,-0.029559582,-0.016186597,-0.988828342,-1.146541728,-2.062950644,-1.946985621,-2.092146223,-2.315204766,-2.656417654,-3.609910759,0.31110525,-0.66159675,-13.79767848,-13.93984058,-15.46907941,-13.39449153,-14.32121756,-11.86376332,-9.081220149,-5.158436296 -2503,D155T,0.02949894,-0.26524323,-1.56228049,-2.21896262,-3.098885595,0.001330697,0.071682359,-0.012684479,0.008483184,-0.173113191,-0.357373268,-1.458564485,-1.665996495,-2.038310236,-2.399615003,-2.380732917,-3.817038272,3.193611821,1.55458012,-11.11340296,-13.17378031,-11.97400218,-9.644707405,-11.39491141,-9.37961351,-8.076540044,-4.355533942 -2504,D155W,0.014548159,-0.963763031,-2.381639916,-2.344901135,-3.378654397,-0.020864026,0.045844661,-0.016748343,-0.023315359,-0.851832376,-1.075693686,-2.771052718,-1.992227113,-2.317374713,-2.372427556,-3.040008636,-3.717300158,0.383932525,-0.605268424,-15.39729887,-16.81671275,-15.45672027,-14.24447545,-16.2107851,-14.2578008,-9.296415058,-5.717255021 -2505,D155V,0.0306635,-0.367121416,-1.571742981,-2.41396719,-2.95260037,-0.030931757,0.056306691,0.005020308,-0.056937882,-0.313579575,-0.420663256,-1.606677664,-1.536808297,-2.123036436,-2.704897943,-2.896822881,-3.008377859,2.636924189,0.931063943,-11.81194681,-15.08659561,-12.31832057,-9.509256859,-12.72650036,-9.419060669,-7.0874141,-2.353097959 -2506,D155Y,0.003428328,-0.90280407,-2.231455816,-2.355333726,-2.717875648,-0.029024407,0.057534246,-0.05067759,0.00488892,-0.80382465,-1.00178349,-1.667093586,-2.795818045,-2.116505569,-2.594161882,-2.538109496,-2.897641799,3.294903276,1.382545813,-13.94283793,-17.79250107,-15.6735612,-11.74413324,-13.55660533,-10.94738882,-7.382147565,-2.984141441 -2507,H156A,0.000790751,-0.014790748,-0.013775122,-0.037463351,-0.069156908,-0.004613879,-0.057818935,0.059400437,-0.020166752,0.017633285,-0.04721478,-0.003919562,-0.023630681,-0.026940813,-0.047985888,-0.045649842,-0.092663973,1.216623114,2.35890501,0.554502347,-0.078559387,0.467002213,1.583049004,0.230505196,0.570514709,-2.86130536,0.72643388 -2508,H156C,0.020529604,-0.026537667,0.00045868,-0.014785688,-0.105137007,-0.004878065,-0.021974345,0.063033553,-0.065953279,-0.030274909,-0.022800424,0.013275179,-0.01235782,-0.013353091,-0.016218284,-0.122160001,-0.088114013,1.398410085,2.315654605,-3.445492822,-3.462221413,-3.171059914,-3.105626266,-3.357142784,-4.131413734,-6.182460048,-3.128659228 -2509,H156E,-0.037762956,-0.004816341,-0.026718718,-0.047354441,-0.060026062,-0.054687259,-0.054157405,-0.021368507,0.02297905,0.007668952,-0.017301633,-0.016207016,-0.03723042,-0.063252606,-0.031456276,-0.057230477,-0.062821647,1.215770099,2.256930721,1.240963054,0.779028107,1.419941666,1.663993355,0.907555809,1.434296333,-2.406000821,1.173918051 -2510,H156D,-0.025354699,0.016333765,-0.011982939,0.005269489,-0.030105332,0.009855463,-0.029827015,-0.020882383,0.036641783,0.015788006,0.016879523,-0.006846,-0.017119878,-0.027356377,0.037895355,-0.012306783,-0.04790388,1.202027832,2.511116909,0.844047131,0.855781097,0.901944038,1.536604256,0.806573563,0.119332703,-2.8425579,1.226821504 -2511,H156G,0.009082244,-0.011025031,-0.023313008,-0.023926916,-0.087994099,-0.006198773,-0.037914523,0.05607901,-0.018761122,0.019916907,-0.041966968,0.008720235,-0.055346251,-0.01456751,-0.033286321,-0.055661071,-0.120327127,1.433653085,2.577141226,0.491278864,-0.565281364,0.3980131,1.437023872,0.50423217,0.68240654,-2.830481761,0.485418576 -2512,H156F,-0.006938268,0.018674223,0.022466152,0.002627122,0.009488401,-0.030445031,-0.011809397,-0.002067139,0.013887322,0.042887611,-0.005539165,0.053878397,-0.008946094,-0.002073009,0.007327252,0.034957439,-0.015980638,1.132951632,2.714552607,-4.550800871,-3.773891388,-3.639100235,-5.003751221,-4.462842361,-5.874419151,-6.578897344,-3.719539748 -2513,H156I,0.009215622,-0.040755232,-0.039775838,-0.052229063,-0.155017382,-0.047527992,-0.027372265,0.045803509,-0.002574528,-0.002109198,-0.079401265,-0.01205723,-0.067494446,-0.04591243,-0.058545695,-0.133365811,-0.176668953,1.402876335,2.227808267,-2.441491991,-2.515961052,-2.093189796,-2.30176265,-2.158230331,-3.138316124,-5.042377543,-1.857423461 -2514,H156K,-0.067011842,-0.026198547,-0.003989321,-0.003006977,-0.023280442,-0.010627067,-0.061403301,-0.072620382,0.061927561,0.011090227,-0.06348732,0.050448234,-0.058426876,-0.005524669,-0.000489285,-0.019587873,-0.02697301,1.289824957,2.530269883,0.656068959,0.316260223,1.042140244,0.578792274,0.802649826,0.540502228,-2.715062893,1.506115108 -2515,H156M,0.0273606,0.028954825,0.030014758,0.028995526,0.013323853,-0.012058569,-0.013935778,0.068656977,-0.016352263,0.035718806,0.022190843,0.044585861,0.015443655,0.009531082,0.04845997,-0.020081785,0.046729491,1.145623364,2.558118927,-1.508091638,-2.022221268,-1.313295349,-0.76925148,-1.350404381,-2.085285713,-4.425726222,-1.605335791 -2516,H156L,-0.008777801,-0.012408425,-0.000862018,-0.018975888,-0.057332813,-0.005969574,-0.04873799,0.031182389,-0.017795249,0.005752998,-0.030569847,0.031009441,-0.032733476,-0.022130003,-0.015821772,-0.025392261,-0.089273364,1.274597881,2.547224212,-1.296251505,-1.640441788,-0.823567719,-0.930896393,-1.087508385,-1.998843239,-3.908018778,-1.282033687 -2517,H156N,-0.075020577,-0.023835533,0.035573827,0.000245875,0.000899269,-0.01195473,-0.082497311,-0.067543843,0.006163373,0.005927321,-0.053598387,0.045875765,0.025271889,-0.022665807,0.023157557,0.017778823,-0.015980285,1.229041836,2.626579444,0.842663411,0.338358139,0.791988831,0.987272766,1.706707932,0.388989388,-1.550499162,0.691510105 -2518,H156Q,-0.035321248,0.006921984,-0.014062934,-0.028171835,-0.03615346,0.005126956,-0.025955205,-0.044687291,-0.031855791,0.017866987,-0.00402302,0.00817785,-0.036303718,-0.022739432,-0.033604237,-0.014396074,-0.057910845,1.299989623,2.656061751,1.137905292,0.0897827,1.406170601,1.286998787,1.36230999,1.544264381,-1.328632852,0.61780149 -2519,H156P,0.013109826,-0.017643746,-0.008143436,-0.025070529,-0.099892424,-0.011720571,-0.040235192,0.066454844,-0.022467425,0.011110215,-0.046397706,0.005448981,-0.021735852,-0.028359577,-0.021781481,-0.072473417,-0.127311431,1.360388204,2.4288243,0.796035635,-0.201006561,1.508563133,1.746077835,0.397382637,0.529161133,-2.271937013,0.812610269 -2520,H156S,0.013185254,-0.023367033,-0.010695743,-0.010834194,-0.044113082,-0.01676159,-0.039234964,0.065605471,0.011227791,0.003577463,-0.050311529,0.011619984,-0.03301147,-0.020846313,-0.000822075,-0.015306662,-0.072919502,1.205719968,2.562671872,0.985202245,0.658240845,1.2812285,1.191527809,0.944833473,0.850180595,-1.7927763,0.93399516 -2521,H156R,0.00577665,-0.011233411,-0.01747603,-0.038466958,-0.050996883,-0.002497452,-0.026565659,0.038118959,-0.013646666,0.000573681,-0.023040503,-0.004611149,-0.030340911,-0.042605682,-0.034328233,-0.036668096,-0.06532567,1.310160679,2.512602045,0.626684258,-0.169053291,0.653560593,1.333411972,0.03436438,1.281137634,-2.124178407,1.08640425 -2522,H156T,0.010346685,-0.009582917,-0.010314859,-0.009820461,-0.026805845,-0.02336808,-0.043461836,0.064155205,0.016238285,0.047302013,-0.066467847,0.034949527,-0.055579245,0.023591427,-0.043232349,0.026456351,-0.08006804,1.251121256,2.93995983,1.27834319,1.014416122,1.513854446,1.651493874,1.159904701,1.052046806,-2.70010411,1.671011748 -2523,H156W,-0.025378777,0.009689667,-0.005721979,0.014182097,-0.042865849,-0.014523413,-0.070279275,0.019521722,-0.011595542,0.055117669,-0.035738336,0.022825967,-0.034269925,0.01136923,0.016994964,-0.032056797,-0.0536749,1.192084354,2.469933323,-3.822954973,-3.68084642,-3.427587982,-3.560346733,-4.161780327,-4.284213402,-6.545712343,-3.473903061 -2524,H156V,-0.036787788,-0.028977481,-0.030686662,-0.037564021,-0.079730457,-0.021039885,-0.100679689,0.027104114,-0.020340733,-0.011958553,-0.045996409,0.028093053,-0.089466377,-0.017841799,-0.057286242,-0.05447889,-0.104982024,1.366521357,2.44779904,-1.247606227,-0.922966278,-1.104612732,-1.07015863,-1.475693794,-1.664599701,-4.437423739,-0.600127589 -2525,H156Y,-0.064005058,0.020429122,0.012173882,-0.027288503,-0.002911655,0.041098586,-0.059093424,-0.068916692,-0.035449785,0.070976361,-0.030118117,0.042229301,-0.017881537,-0.008059077,-0.046517929,0.028469435,-0.034292744,1.125323858,2.573922852,-3.058438542,-2.54501503,-2.665190285,-3.271963844,-3.025360451,-3.784663101,-5.347297279,-2.127439768 -2526,V157A,0.007986192,0.009309957,-0.021504657,-0.037041243,-0.049961013,-0.045121338,-0.02201055,0.037982933,0.027922016,-0.021914187,0.0405341,-0.063905856,0.020896542,-0.049213235,-0.024869251,-0.079531391,-0.020390634,1.329353049,2.299317259,-3.169581964,-3.659349556,-3.425468437,-2.785059807,-2.948949608,-3.029082413,-4.279568631,-1.439897602 -2527,V157C,0.084954012,0.012562658,0.025972173,0.012285342,-0.134334239,-0.004265398,0.078120435,0.091787589,-0.002809371,-0.062655307,0.087780622,-0.064389724,0.11633407,-0.038264444,0.062835127,-0.162790796,-0.105877681,1.391379159,2.195558388,-7.321403911,-7.892734428,-7.202978905,-6.863465248,-7.244085747,-7.403755226,-7.986200681,-5.469944189 -2528,V157E,-0.106966422,0.017066138,-0.041678455,-0.025078306,-0.058903587,-0.004520905,-0.153480035,-0.060452809,-0.056893666,0.067774528,-0.033642253,-0.023431618,-0.059925292,0.015065903,-0.065222515,-0.035689096,-0.082118078,1.117367883,2.476741575,-3.25021282,-3.876705284,-2.877288437,-3.41701593,-3.342827042,-2.737227409,-4.136290335,-1.422860953 -2529,V157D,-0.002044337,0.005075446,-0.00477866,-0.079742038,-0.082892483,-0.097440301,-0.0628855,0.058796827,0.00106587,-0.003914973,0.014065864,0.00782752,-0.01738484,-0.070744501,-0.088739575,-0.150696235,-0.01508873,1.463569959,2.22689915,-4.612984422,-5.450246155,-4.859641068,-4.161918457,-3.95824292,-4.634873512,-5.801194455,-0.513878806 -2530,V157G,0.107945948,0.191189492,0.01376128,0.003002917,-0.292355779,-0.011331775,0.074179539,0.141712356,0.027074473,0.180638887,0.201740097,0.038368338,-0.010845778,0.057385578,-0.051379744,-0.212819433,-0.371892125,1.095799386,1.869075274,-6.022080222,-7.648190269,-4.692545639,-5.270106941,-5.896085098,-6.60347316,-5.548830965,-0.548143617 -2531,V157F,-0.007756688,0.003720795,-0.022351098,-0.055792264,-0.033174397,-0.079265779,-0.019010585,0.003497209,0.022708491,-0.025023884,0.032465473,-0.073198806,0.028496611,-0.016428786,-0.095155741,-0.113066796,0.046718002,1.400904922,2.277511735,-4.670477209,-4.969606888,-4.352804314,-4.898512177,-4.524869492,-4.606593178,-5.820973963,-4.535583336 -2532,V157I,0.008875801,0.035812307,0.014339179,0.008850037,-0.016144166,-0.087609895,-0.016888417,0.034640018,0.009676287,0.047326115,0.024298498,0.041091196,-0.012412838,0.014698422,0.003001651,0.018967839,-0.051256171,1.112279219,2.632444793,-1.640933986,-1.62044603,-1.525478676,-1.751361633,-1.825927551,-1.481456039,-2.819401069,-2.073549086 -2533,V157H,-0.044571051,0.060833498,0.033880164,0.000340679,-0.028670375,-0.075986231,-0.09326186,0.004119758,-0.069118608,0.048976245,0.07269075,0.055996382,0.011763946,0.047731714,-0.047050356,-0.045777879,-0.01156287,1.19428499,2.477242401,-4.302297868,-4.704184357,-4.766113251,-4.063290131,-3.787782104,-4.190119499,-5.135493435,-1.560019028 -2534,V157K,0.022282207,0.014994963,-0.008282013,0.000859564,-0.06893156,0.016136523,-0.031403631,0.075968044,-0.031896208,-0.017291521,0.047281446,-0.051811308,0.035247283,-0.005612198,0.007331325,-0.098633423,-0.039229696,1.343734125,2.293345447,-3.253023756,-3.905307495,-3.620977875,-3.685114174,-3.029333694,-2.024385544,-4.328695129,-1.929641125 -2535,V157M,0.02340169,-0.019685983,-0.019215341,0.011822794,-0.110101585,-0.078687083,0.014002998,0.032800381,0.05095052,-0.05962771,0.020255745,-0.039449345,0.001018663,-0.038077633,0.061723221,-0.118598559,-0.101604611,1.396889719,2.271492265,-3.099042305,-2.393574715,-2.770079826,-3.150112404,-3.352951286,-3.828493294,-3.943860156,-3.458638005 -2536,V157L,-0.016502679,0.00856212,-0.024722349,-0.027218815,-0.159833685,-0.051930041,-0.030786418,-0.00221894,-0.020383651,-0.023481096,0.040605336,-0.056048906,0.006604208,-0.031286181,-0.023151449,-0.161697204,-0.157970165,1.612664549,2.351197861,-2.975976044,-2.94330793,-3.074684273,-2.514048073,-2.625054993,-3.72278495,-5.01423233,-2.978221397 -2537,V157N,0.000198755,0.03000856,-0.031966483,-0.004686483,-0.148758043,0.020972032,-0.002118608,0.002516117,-0.023868458,0.019487978,0.040529142,-0.085588202,0.021655236,-0.009035113,-0.000337853,-0.133638187,-0.163877899,1.288931804,2.211570657,-4.727192067,-5.578263596,-4.589474457,-5.069303925,-4.866163574,-3.532754784,-6.067978776,-0.871591631 -2538,V157Q,-0.028725188,0.033604028,0.033820561,-0.061760167,-0.034791114,-0.084827921,-0.101191564,0.043741189,-0.032561979,0.012268268,0.054939788,-0.010704249,0.078345371,-0.032506184,-0.09101415,-0.061165621,-0.008416606,1.404070826,2.462408032,-2.952774988,-3.366416473,-3.414064003,-2.88609211,-2.762900558,-2.334401794,-4.400198822,-1.245940109 -2539,V157P,-0.023004699,0.03979491,-0.827622299,-1.912090996,-2.508478619,-0.015592914,-0.014112959,-0.031896438,-0.024791543,0.015971676,0.063618144,-0.537258239,-1.117986359,-1.731426245,-2.092755747,-2.316537655,-2.700419583,1.74226861,0.84392402,-7.171530978,-8.132885483,-6.945380249,-6.580752251,-6.756553558,-7.442083351,-6.160434565,-4.153996184 -2540,V157S,-0.004358762,0.033163936,-0.001189644,-0.009443115,-0.068319607,-0.06028089,-0.038997988,0.030280465,-0.01391897,0.005455021,0.06087285,-0.019964785,0.017585497,-0.005281906,-0.013604324,-0.047715981,-0.088923233,1.262132994,2.44424151,-3.60658513,-4.741048286,-3.549595406,-3.312970474,-3.246620186,-3.182691299,-4.140282437,-1.38262434 -2541,V157R,0.011059736,0.04024141,0.019991246,-0.012669237,-0.100719758,0.005986242,-0.013690598,0.03581007,-0.006412719,0.018381351,0.062101468,-0.012765894,0.052748386,-0.028494431,0.003155957,-0.120336125,-0.08110339,1.409320366,2.280302418,-4.568367793,-5.627642571,-4.679623375,-3.990448166,-3.775651016,-4.768473839,-5.734794799,-1.423671343 -2542,V157T,-0.022025257,0.019373934,0.004638975,-0.011490753,-0.050944736,-0.009981433,-0.050543999,0.006493486,-0.014280938,0.018145144,0.020602723,-0.007243717,0.016521667,-0.012138635,-0.01084287,-0.069706728,-0.032182743,1.359603318,2.454671115,-1.154105035,-1.484788383,-1.075494499,-1.170520035,-1.359177597,-0.680544662,-1.968892619,-0.629145117 -2543,V157W,0.007498572,0.071943872,0.046693488,-0.014799064,-0.063348543,0.006335748,-0.008847174,0.023844318,-0.02232801,0.052239618,0.091648125,0.016267613,0.077119362,0.013688938,-0.043287066,-0.094570199,-0.032126886,1.346578525,2.32614318,-5.876466684,-6.500454124,-5.568955223,-5.456357124,-5.407332962,-6.449233986,-6.824008517,-4.798203921 -2544,V157Y,-0.026986843,0.089823681,0.071057583,0.019410524,0.0042194,-0.054327478,-0.062310576,0.008336891,0.008647984,0.101942074,0.077705288,0.080452194,0.061662971,0.07784526,-0.039024213,0.017561899,-0.009123099,1.301330514,2.932170999,-4.273006175,-4.279589096,-3.33531147,-5.004244934,-4.744499374,-4.001386002,-4.798036844,-3.535081611 -2545,T158A,-0.028880463,-0.011968048,-0.0169454,-0.121961116,-1.75776431,-0.050037362,-0.030818876,-0.026942049,-0.044752918,-0.016594137,-0.007341958,-0.015432313,-0.018458486,-0.071642508,-0.172279723,-1.706419375,-1.809109245,0.91354021,1.322989124,-6.74590338,-6.753515366,-6.024180199,-6.620997185,-7.572899918,-6.757924232,-7.615992122,-5.09847707 -2546,T158C,0.014937236,-0.059811937,-0.352633716,-1.979025918,-2.074436607,-0.066666054,0.03415179,-0.004277319,-0.017442138,-0.097693744,-0.021930129,-0.186455551,-0.51881188,-1.461092812,-2.496959023,-2.195292493,-1.95358072,2.521829597,1.552393897,-8.816079497,-9.111968544,-7.680197968,-9.358273827,-8.877467171,-9.052489975,-8.306899929,-5.248514957 -2547,T158E,-0.086507447,-1.175465311,-1.994885235,-2.461750696,-2.826795965,-0.038013063,-0.104601067,-0.068413827,-0.0296095,-0.973438626,-1.377491996,-2.142191176,-1.847579294,-2.101827499,-2.821673893,-2.676326337,-2.977265593,0.339241367,-0.633590368,-10.49318647,-10.61954129,-8.337820236,-10.82387936,-12.14736702,-10.53732446,-9.656081126,-7.636737711 -2548,T158D,0.095400055,-0.586628133,-2.054794181,-2.158160277,-2.857708937,-0.06140133,0.146878773,0.043921336,-0.027128158,-0.494761846,-0.678494419,-2.402412347,-1.707176014,-2.237109933,-2.079210621,-2.635517512,-3.079900362,0.401892611,-0.486329356,-10.78483629,-10.97438513,-9.745017288,-11.03253608,-11.59516908,-10.57707387,-9.710414099,-7.636737711 -2549,T158G,-0.028441239,-0.010144088,-0.038873325,-0.957233643,-2.322613955,-0.012227968,-0.011574282,-0.045308195,-0.034284426,-0.020700154,0.000411979,-0.052958626,-0.024788023,-0.44292479,-1.471542495,-2.04714551,-2.598082399,1.731142627,1.35983682,-5.615739685,-6.421732544,-5.241361717,-5.506715347,-6.070659134,-4.838229683,-6.376746154,-4.621285299 -2550,T158F,0.061257886,0.013099162,-0.031020341,0.023313035,-1.662542725,0.044757627,0.117896604,0.004619168,-0.014174414,-0.020031826,0.046230149,-0.131266331,0.06922565,-0.045145163,0.091771232,-1.686590791,-1.638494659,0.808514785,1.318118766,-6.339188605,-6.327151306,-5.758313309,-7.236921394,-6.454403725,-5.91915329,-5.575406968,-1.814040475 -2551,T158I,0.090180352,0.042909661,-0.289801071,-2.070084083,-2.619117745,0.063354391,0.132504931,0.047855773,-0.076993383,-0.031875053,0.117694375,-0.244678629,-0.334923513,-1.464727097,-2.675441069,-2.40720272,-2.83103277,1.42695384,0.820807066,-6.728567758,-7.633880249,-4.275447784,-7.002468155,-6.90516394,-7.825878662,-6.852960118,-1.621936713 -2552,T158H,-0.005887926,-0.129997274,-1.400016882,-2.376700078,-3.153699718,-0.034001793,0.005409353,-0.017185204,-0.039494911,-0.143775044,-0.116219504,-1.418283014,-1.381750749,-2.508253105,-2.24514705,-2.906660684,-3.400738751,1.045653183,0.089653149,-11.97797269,-12.26819915,-10.0723007,-11.69131924,-12.85421696,-13.00382738,-10.50509567,-9.990787985 -2553,T158K,-0.019445796,-1.420475329,-2.577818355,-2.681184452,-2.657154096,-0.00726131,0.012847469,-0.05173906,-0.103740919,-1.658557519,-1.182393138,-2.299036291,-2.856600418,-2.434763874,-2.92760503,-2.532141456,-2.782166735,-0.083982765,-1.079512114,-10.71000277,-10.39429324,-9.358348595,-10.42260023,-11.86147739,-11.51329439,-9.705296779,-7.636737711 -2554,T158M,-0.088305607,-0.050163998,-0.371490407,-2.118906559,-2.833436831,-0.045057174,-0.069381223,-0.107229991,-0.068086765,-0.045216517,-0.055111479,-0.227541874,-0.515438939,-1.935366224,-2.302446894,-2.509865062,-3.157008599,1.227098972,0.692747039,-7.404449721,-7.994227478,-5.952948532,-7.277151054,-8.556643692,-7.241277847,-5.79062572,-2.88888606 -2555,T158L,-0.074344656,-0.35571971,-1.565843171,-2.350798219,-2.71824293,-0.011836931,-0.069025053,-0.079664259,-0.032444284,-0.198216444,-0.513222975,-1.45411917,-1.677567172,-2.221869967,-2.479726471,-2.465375585,-2.971110274,1.569433326,0.210169994,-7.034857143,-8.723049377,-4.963083763,-7.669684265,-8.545335129,-5.273133179,-6.068846075,-3.178836549 -2556,T158N,0.011774084,-0.191109825,-1.299996099,-2.332028445,-2.847588712,-0.017818102,0.063519486,-0.039971319,-0.02202226,-0.091459631,-0.290760018,-1.148474901,-1.451517297,-2.011201211,-2.652855678,-2.585700049,-3.109477374,2.402240575,0.982821062,-8.914365842,-8.973008232,-7.353449936,-9.233376419,-10.54631986,-8.465674759,-9.025374329,-6.703583065 -2557,T158Q,-0.018011009,-0.410065107,-1.807096801,-2.347026279,-2.561556551,-0.04480964,-0.023189957,-0.012832061,-0.037983725,-0.237807839,-0.582322374,-1.658693942,-1.955499659,-2.220390256,-2.473662302,-2.493859098,-2.629254003,1.146779821,0.041487212,-9.627094266,-9.871858261,-7.307986794,-9.874044067,-11.7535477,-9.328034508,-7.990517695,-4.709698207 -2558,T158P,-0.047265934,-0.861978129,-1.937056479,-2.371801492,-2.693836426,-0.04161215,-0.03852653,-0.056005337,-0.001364811,-0.708896908,-1.015059349,-1.897852844,-1.976260114,-2.179708461,-2.563894522,-2.550087316,-2.837585535,2.920946179,0.953996006,-10.28377697,-10.21614412,-9.169962257,-10.40614236,-11.48169687,-10.14493927,-9.580546624,-7.6068904 -2559,T158S,0.015033753,0.011266874,-0.020908291,0.004136106,-0.018715579,-0.054606494,0.003137411,0.026930094,-0.034150704,-0.023250323,0.04578407,-0.001956087,-0.039860495,-0.017824458,0.02609667,-0.038154924,0.000723766,1.441341456,2.634085791,-1.995040804,-1.887696579,-2.629198944,-2.067860832,-2.901416771,-0.489030891,-2.707939883,-1.804535775 -2560,T158R,0.000780494,-1.585324976,-2.073623984,-2.313490717,-2.829050984,-0.024743489,0.000845161,0.000715826,-0.118243952,-1.710866618,-1.459783333,-2.147225408,-2.00002256,-2.203771744,-2.42320969,-2.477240586,-3.180861382,-0.235481218,-1.118950065,-11.18140742,-11.19978569,-8.817960403,-11.50193285,-12.57058962,-11.81676853,-9.647283605,-7.636737711 -2561,T158W,-0.001048914,-0.852970888,-1.935432754,-2.456870449,-2.855389113,-0.109542547,0.002327036,-0.004424863,0.013381811,-0.755467532,-0.950474243,-1.899396498,-1.971469009,-1.792086031,-3.121654867,-2.734561654,-2.976216572,3.502028469,1.558197055,-10.85864467,-11.29701408,-9.937060265,-11.85011852,-11.22084641,-9.988184059,-8.610340115,-6.026166154 -2562,T158V,-0.041539086,0.016103404,-0.011243436,-1.232293488,-2.060039083,-0.018751731,-0.016265212,-0.06681296,-0.020814413,0.014433643,0.017773164,-0.009772116,-0.012714756,-0.706765618,-1.757821357,-2.062421216,-2.057656949,1.812751878,1.384383882,-7.682841161,-8.622737572,-5.495376274,-7.336580681,-8.307325401,-8.652185875,-6.931224667,-2.914247331 -2563,T158Y,-0.057431451,-0.602050125,-1.741436873,-2.505912618,-2.632397259,-0.018531815,-0.074692985,-0.040169916,0.006374023,-0.48246626,-0.721633989,-1.533119497,-1.949754248,-2.51394512,-2.497880115,-2.611322702,-2.653471815,1.743393148,0.237707975,-9.692380902,-9.5484132,-9.006973946,-10.43711009,-8.428070961,-11.04133631,-7.420787025,-4.970833928 -2564,R159A,-0.041589751,0.018099699,-0.016078471,-0.009174969,-1.81998913,-0.054365796,-0.038926343,-0.044253158,-0.140360605,0.037816101,-0.001616704,-0.003455391,-0.028701551,0.020323467,-0.038673405,-1.573000696,-2.066977563,0.606022212,1.312633163,-10.06333203,-9.202413597,-9.392203819,-10.83267946,-11.05130489,-9.838058373,-8.611336742,-2.373176647 -2565,R159C,-0.051000738,-0.045488391,-0.044300819,-0.043935397,-1.598124144,-0.072430628,-0.026491672,-0.075509803,-0.075250295,-0.006108904,-0.084867877,0.014719382,-0.103321019,0.028477809,-0.116348603,-1.295489328,-1.90075896,0.880284109,1.349473777,-12.31606937,-11.27984914,-12.00466442,-14.16630684,-12.73819745,-11.39132899,-9.266848145,-5.30288059 -2566,R159E,0.031932327,-0.015735218,-0.003915812,-0.073011111,-1.826000916,-0.168366129,0.054133043,0.00973161,-0.099250572,0.067088489,-0.098558925,0.025082238,-0.032913861,0.027545461,-0.173567683,-1.585650944,-2.066350888,0.665608126,1.315719665,-8.984364507,-7.497812592,-9.552730087,-11.35117878,-8.256558373,-8.263542702,-7.296778802,-2.43883982 -2567,R159D,0.003476165,0.042122712,-0.658410457,-1.808325703,-2.750766539,-0.107587279,0.048747947,-0.041795618,-0.151335045,0.029341793,0.05490363,-0.353493241,-0.963327673,-1.549782175,-2.06686923,-2.44677643,-3.054756647,1.575282348,0.842614192,-10.18176155,-10.512965,-10.97441766,-11.71783959,-9.322845688,-8.380739822,-6.945195123,-2.863109062 -2568,R159G,-0.002218888,-0.006202985,0.002594156,-1.029913777,-2.092619471,-0.06335971,0.021176285,-0.02561406,-0.047382213,-0.00142319,-0.010982779,0.006981065,-0.001792753,-0.535363936,-1.524463618,-1.765433114,-2.419805827,1.808348249,1.477045394,-10.89755506,-7.339528839,-11.07260362,-12.56170866,-12.214936,-11.29899818,-8.068370701,-3.500316106 -2569,R159F,0.146300946,0.054935495,0.140125367,0.070928387,-1.18597189,0.007522233,0.200500933,0.092100958,-0.569334847,-0.013684553,0.123555543,0.056681224,0.223569509,0.021205283,0.120651491,-1.38607859,-0.985865189,0.753424606,1.332174313,-12.25968075,-12.29506146,-12.09029714,-13.31502723,-11.73356046,-11.86445745,-7.774148651,-4.100442229 -2570,R159I,-0.172504477,-0.10268725,-0.074923104,-0.075693857,-1.415053588,0.074875835,-0.147759091,-0.197249862,-0.444396111,0.052292674,-0.257667174,0.013632821,-0.163479028,0.109990803,-0.261378516,-1.471250199,-1.358856977,0.478383924,1.311922174,-11.23793614,-11.6746657,-11.8942569,-12.93797182,-9.853796165,-9.828990105,-7.114581332,-3.166354649 -2571,R159H,0.038028575,0.020620135,0.011238471,-0.005179846,-0.024222481,0.010654299,0.073903434,0.002153715,-0.031239354,-0.005955111,0.04719538,0.012121103,0.010355839,-0.042974691,0.032614999,-0.021729489,-0.026715472,1.191705043,2.506115455,-5.931717001,-5.950411255,-6.185365845,-7.022521423,-5.826043587,-4.674242897,-5.18132903,-2.760801921 -2572,R159K,-0.009028911,-0.023887063,-0.023743115,-0.078192129,-0.213063427,-0.082231903,-0.042528469,0.024470647,-0.371845444,0.00265531,-0.050429436,0.081190724,-0.128676954,-0.002928396,-0.153455862,-0.248416601,-0.177710252,1.590887955,2.182387887,-8.513595859,-6.645778511,-9.147201752,-10.24097353,-7.44688295,-9.087142555,-6.739181677,-2.265574989 -2573,R159M,0.013738744,0.027321752,0.005360126,0.02419171,-1.835369183,-0.123062528,0.025238125,0.002239363,-0.211117899,0.029470264,0.025173239,-0.017187485,0.027907736,0.020221604,0.028161816,-1.165568191,-2.505170174,0.59063464,1.330427803,-10.60933649,-9.401110977,-11.01148328,-12.88050896,-9.669185387,-10.08439388,-8.234130867,-4.438849478 -2574,R159L,-0.0338852,-0.039064701,-0.005251084,-0.069197161,-1.899057722,0.013282291,-0.004527408,-0.063242991,-0.285895176,-0.01133377,-0.066795631,-0.016412201,0.005910033,-0.028147009,-0.110247312,-1.655403626,-2.142711817,0.850632225,1.323265426,-9.01914816,-9.008939041,-9.475481071,-10.54249068,-7.820228462,-8.248601547,-6.931739432,-3.526506195 -2575,R159N,0.064347058,-0.047621031,-0.048171944,0.038834367,-1.158634112,-0.040648237,0.102605463,0.026088653,-0.205514022,-0.018574885,-0.076667176,0.047651908,-0.143995795,0.040181209,0.037487525,-0.624317755,-1.692950468,0.677908692,1.403005034,-9.233042659,-8.491120781,-10.86623704,-10.5436887,-8.140628365,-8.123538414,-6.973668223,-2.495390487 -2576,R159Q,0.033417452,0.058159924,0.010645542,0.064706117,-0.117895174,-0.015205783,0.027813917,0.039020986,-0.06537309,0.063450975,0.052868872,-0.00156082,0.022851903,0.064207447,0.065204786,-0.136088619,-0.099701728,1.398049603,2.276237523,-5.358376759,-3.935880661,-6.341570549,-6.797848366,-4.913378532,-4.803205688,-4.807205271,-2.147814404 -2577,R159P,-0.006923264,-1.343820663,-1.655194266,-1.822659523,-2.195801354,-0.042590282,0.029434188,-0.043280715,-0.296960323,-1.331036313,-1.356605012,-1.450403254,-1.859985277,-1.585994348,-2.059324697,-1.782003307,-2.6095994,4.390451871,2.459729036,-11.83971781,-10.84034904,-11.43172881,-12.65912663,-12.61056439,-11.65682016,-9.183697047,-5.372069978 -2578,R159S,-0.025436437,0.008900098,0.006914446,-0.000909684,-0.476218612,-0.024304114,-0.03473233,-0.016140543,-0.277366466,-0.000932283,0.018732479,0.004165614,0.009663277,0.008515159,-0.010334527,-0.385594965,-0.566842259,0.626323886,1.453160789,-7.431824477,-6.534859573,-7.154044098,-9.169239365,-7.338502831,-6.962476517,-6.851931594,-2.126348867 -2579,R159T,-0.027211309,0.00382007,0.02618152,0.022318705,-0.293486986,0.029490659,-0.009337243,-0.045085375,-0.172423615,0.033378944,-0.025738804,0.0571849,-0.004821861,0.042994483,0.001642927,-0.202567156,-0.384406815,1.244270113,2.034478831,-9.118734329,-7.468052483,-8.486753929,-11.49363973,-9.421552887,-8.723672615,-7.211216989,-2.496908887 -2580,R159W,-0.021042253,0.021291951,0.01241816,0.009298701,-1.56451437,-0.008446434,-0.011811265,-0.03027324,-0.142589896,0.066272912,-0.023689011,0.04562425,-0.020787931,0.068526283,-0.049928881,-1.572108371,-1.556920369,0.465878978,1.307066499,-11.35921426,-11.56165385,-11.27827748,-12.56290557,-12.03142344,-9.361810951,-8.951126341,-4.610138605 -2581,R159V,-0.022112763,-0.004521954,-0.004261753,0.032257454,-1.502183898,0.016255024,0.011722264,-0.05594779,-0.01876313,0.030453944,-0.039497851,0.000432145,-0.00895565,0.02930425,0.035210657,-1.27886862,-1.725499176,0.672655209,1.331662233,-9.958154843,-9.42711216,-10.2285022,-11.58786279,-9.314030937,-9.233266121,-7.054396529,-1.937835572 -2582,R159Y,-0.036953786,-0.030407612,-0.018138127,-0.007278884,-1.576523906,-0.081381179,-0.054220714,-0.019686857,-0.428601844,-0.115674092,0.054858869,-0.024434521,-0.011841732,-0.041926303,0.027368536,-1.629116638,-1.523931173,0.795335973,1.318408427,-12.4374916,-13.39978756,-13.73899608,-13.61253504,-11.48891695,-9.947222343,-8.265361996,-4.581534543 -2583,L160A,0.027406827,0.00318338,-0.009497183,-0.007459671,-0.20360832,0.009191616,0.053186612,0.001627041,-0.007138211,0.031725311,-0.025358551,0.019343371,-0.038337736,-0.028661322,0.013741981,-0.18373275,-0.223483889,1.472318221,2.208962197,-9.627284598,-9.557653595,-9.578898613,-9.436677498,-11.97117282,-7.592020462,-6.431491474,-2.943898503 -2584,L160C,-0.016330782,-0.048708549,-0.024557762,-0.056976938,-0.091992954,0.115533916,-0.004382021,-0.028279543,-0.007044381,-0.046933944,-0.050483154,-0.019849968,-0.029265556,-0.088903888,-0.025049987,-0.140811379,-0.043174529,1.538648525,2.323131466,-9.786634557,-10.7983765,-8.938656822,-11.45994267,-11.84915794,-5.887038849,-6.668783029,-4.078032847 -2585,L160E,-0.001251956,-0.054386705,-1.09653147,-1.935660269,-2.544298692,-0.066568312,0.053292472,-0.055796383,-0.029958389,0.0000231,-0.108796509,-0.823026322,-1.370036618,-1.90911358,-1.962206957,-2.140302118,-2.948295266,3.422476863,2.079461125,-12.86631747,-12.43247539,-12.32604844,-14.11301208,-15.0241438,-10.43590766,-8.249225809,-5.79739118 -2586,L160D,-0.05402176,-0.105071612,-0.806451564,-2.224848114,-2.836727602,-0.066416496,-0.042430262,-0.065613257,-0.020231871,-0.136840518,-0.073302706,-0.317309701,-1.295593427,-1.500306973,-2.949389255,-2.539609985,-3.133845218,1.556864333,0.849537681,-14.66176838,-15.20248042,-13.801995,-15.44929353,-16.78318984,-12.07188309,-9.524716155,-7.845160434 -2587,L160G,-0.03006907,-0.015225293,0.00706394,-1.256283636,-2.25622662,-0.04094174,0.002821849,-0.062959988,-0.066827684,-0.003770238,-0.026680347,0.029104475,-0.014976596,-0.7886643,-1.723902971,-2.037492964,-2.474960276,1.969711221,1.447864072,-14.21309673,-14.50839871,-13.43961076,-15.26296598,-16.30214053,-11.55236767,-9.330793128,-7.35093058 -2588,L160F,0.00864185,-0.016097075,0.012485343,-0.016523232,-0.571760779,0.030664561,0.043449811,-0.026166112,0.025545592,-0.03204472,-0.00014943,0.003176987,0.021793698,-0.075611033,0.042564569,-0.542042442,-0.601479115,1.411205759,1.755663986,-7.784257086,-8.054141212,-6.199143089,-10.04012254,-8.976743782,-5.651134804,-5.828534096,-2.346543718 -2589,L160I,-0.022238085,-0.024254286,0.028413255,-0.02777693,-0.040497089,0.135072009,-0.018657061,-0.025819108,-0.039166391,-0.015334958,-0.033173614,0.066904283,-0.010077774,0.018206967,-0.073760826,0.026237834,-0.107232012,1.14065731,2.699438039,-5.313907936,-4.470258972,-5.533962959,-6.226030708,-6.798153778,-3.541133263,-5.057680982,-0.982836658 -2590,L160H,0.049192076,0.062327628,0.055868585,-0.029899813,-1.822190357,0.020167281,0.098444351,-0.0000602,0.020251261,0.06938911,0.055266146,0.024003315,0.087733855,-0.090996877,0.031197251,-1.412846479,-2.231534235,0.766427886,1.33038868,-12.2227672,-12.62071987,-10.04760716,-14.09740617,-15.20445188,-9.143650925,-6.662650729,-4.962002266 -2591,L160K,-0.031891398,-0.16359192,-1.968477336,-2.190818654,-2.626606882,0.046964657,0.00126631,-0.065049105,-0.064807977,-0.077876517,-0.249307323,-2.04328294,-1.893671732,-2.226280212,-2.155357095,-2.311340714,-2.94187305,0.488103817,-0.169310472,-13.58613826,-14.43279289,-12.58210751,-14.52227884,-14.94833145,-11.44518063,-9.204322665,-7.241744587 -2592,L160M,0.053924209,0.039047466,0.033406332,-0.00713344,-0.163127337,0.058739464,0.098752245,0.009096173,-0.013715702,0.019083992,0.05901094,0.00902616,0.057786503,-0.027520061,0.013253182,-0.16942084,-0.156833834,1.108109881,1.917584493,-5.492166605,-5.508792099,-5.766561501,-6.557824913,-5.000112801,-4.62754171,-5.129390433,-2.383283309 -2593,L160N,-0.078962771,-0.100658034,-0.026715061,-0.099119234,-1.906073604,0.107774664,-0.03374028,-0.124185262,-0.068073365,-0.133006247,-0.06830982,-0.091766236,0.038336114,-0.132450675,-0.065787793,-1.572898835,-2.239248372,1.151208795,1.359523324,-11.29894044,-11.83654588,-9.9533283,-13.32575392,-13.22144315,-8.157630928,-7.066454711,-5.323084344 -2594,L160Q,0.088110523,-0.005413103,0.008325992,0.045480141,-1.925638658,-0.05662399,0.139200348,0.037020698,-0.050846963,-0.005092839,-0.005733367,-0.050849931,0.067501914,0.008651014,0.082309267,-1.777545554,-2.073731762,0.618209857,1.305969224,-9.856484186,-10.73331866,-9.268839737,-10.78133125,-10.66775456,-7.83117672,-6.830532487,-4.645871965 -2595,L160P,-0.003801273,-0.015809232,0.015403106,-0.929675862,-1.980249427,-0.04100322,0.031670754,-0.039273299,-0.037517363,-0.013398549,-0.018219914,-0.000455523,0.031261734,-0.447670996,-1.411680728,-2.166872757,-1.793626096,1.660382438,1.335879095,-12.25372011,-13.57795429,-12.48347221,-14.93040726,-12.17743493,-8.099331871,-6.478473452,-2.63249621 -2596,L160S,0.001387136,-0.0000279,-0.023298053,-0.013600556,-0.219697753,0.027127415,0.020343581,-0.01756931,-0.012158392,0.011983864,-0.012039713,-0.017045398,-0.029550708,-0.045515802,0.01831469,-0.165666882,-0.273728623,1.417606837,2.164073798,-7.638733841,-6.493185112,-7.946908791,-9.210125999,-9.934336006,-4.609113297,-4.423453778,-3.017735293 -2597,L160R,-0.03361549,-0.837751162,-1.882843034,-2.171020411,-3.392857024,0.007004701,0.020475862,-0.087706842,-0.041744426,-0.67056515,-1.004937174,-1.909453525,-1.856232543,-2.092450797,-2.249590025,-2.84651808,-3.939195967,2.951804427,0.990794217,-12.70903158,-13.25827647,-11.79646166,-13.49984899,-14.61621581,-10.37435497,-7.581360098,-4.490438877 -2598,L160T,0.001835825,0.02036359,0.039080058,0.031371965,-0.27647592,0.046793596,0.002682849,0.000988801,-0.110502912,0.034800015,0.005927164,0.082094046,-0.00393393,0.036596627,0.026147303,-0.217470238,-0.335481601,1.415921567,2.135894609,-10.1569795,-9.967608986,-10.78371256,-10.98184974,-11.58865354,-7.463072693,-6.444531636,-4.104247322 -2599,L160W,-0.043526455,-0.131249371,-1.696969041,-2.312522247,-3.154767154,0.023982413,0.008723746,-0.095776655,-0.068691578,-0.038339498,-0.224159244,-1.795340474,-1.598597608,-2.330520264,-2.29452423,-2.716610761,-3.592923546,0.526994339,-0.044521729,-13.09213344,-13.98359287,-11.61586096,-14.70507079,-14.26106961,-10.89507295,-8.63791186,-6.545641297 -2600,L160V,-0.018478405,-0.015216865,-0.025935664,-0.042705096,-0.052868258,0.147538598,-0.0128867,-0.024070109,-0.017423207,-0.003132138,-0.027301592,-0.029038582,-0.022832745,-0.070031902,-0.015378289,-0.044533582,-0.061202933,1.306301299,2.40719048,-6.454776016,-6.050416077,-5.953768822,-7.709530937,-8.619635643,-3.940528603,-3.73514128,-0.82363787 -2601,L160Y,-0.056448264,0.00716131,-0.988603559,-2.018092101,-2.876429349,-0.029792144,0.008754434,-0.121650962,-0.013920124,0.044579036,-0.030256417,-0.704184284,-1.273022834,-2.142454061,-1.89373014,-2.528544559,-3.224314139,1.745882732,0.697624671,-12.39292286,-13.38622007,-10.50140802,-13.9722675,-14.02762264,-10.07709606,-7.313237053,-4.647974201 -2602,D161A,-0.10834899,-0.061708135,-0.054588507,-0.047746776,-1.724239067,0.075072134,-0.085812963,-0.130885017,-0.007822676,-0.033517133,-0.089899137,-0.043470658,-0.065706355,-0.031212797,-0.064280754,-1.589715114,-1.858763019,0.629716331,1.312791792,-9.398640111,-8.97341468,-9.096185974,-10.9373978,-8.487806137,-9.498395966,-7.543120387,-1.995660061 -2603,D161C,-0.098299153,-0.02249329,-0.015560947,-0.131804351,-1.714345305,0.088411068,-0.066839766,-0.12975854,0.004802231,0.010908957,-0.055895536,0.033313033,-0.064434926,-0.063589881,-0.20001882,-1.788621834,-1.640068776,0.886105627,1.316093513,-15.12244929,-16.733536,-15.05192912,-15.76705503,-13.16540733,-14.89431895,-9.889363994,-6.146411962 -2604,D161E,-0.062340605,-0.032277667,-0.064318609,-0.016074264,-0.941199774,0.08552439,-0.02223435,-0.10244686,-0.032761795,-0.049393073,-0.01516226,-0.06266999,-0.065967228,-0.012927001,-0.019221527,-0.994974698,-0.88742485,0.646441054,1.350604941,-7.835697556,-9.157033813,-7.098443764,-7.385292038,-6.507110626,-9.030607536,-5.515764832,-2.081012008 -2605,D161G,-0.070989359,-0.036877915,-0.072913283,-1.836174552,-3.112543508,0.118624613,-0.046324672,-0.095654046,-0.014571361,-0.038442877,-0.035312953,-0.051654605,-0.09417196,-1.589016789,-2.083332314,-2.637730008,-3.587357007,0.762656806,0.701592952,-12.32699115,-10.29972762,-11.62486637,-14.48310667,-10.74828979,-14.47896528,-7.890100144,-2.33064941 -2606,D161F,-0.105109097,-0.062575472,-0.070186455,-1.84345872,-2.746142514,0.109266267,-0.048536831,-0.161681363,-0.045483401,-0.050100374,-0.075050569,-0.106545536,-0.033827373,-1.604248747,-2.082668693,-2.453092861,-3.039192166,1.002709091,0.719799334,-16.42005556,-15.78095635,-17.21906222,-16.02111028,-16.17914095,-16.90000802,-9.307677934,-4.814406953 -2607,D161I,-0.048420987,-0.039690502,-0.032382938,-0.995981875,-2.754888477,0.063070393,-0.020757769,-0.076084205,-0.052951442,-0.097878636,0.018497632,-0.007170228,-0.057595647,-0.564821618,-1.427142132,-2.63709087,-2.872686083,0.927171874,0.893497188,-13.79137438,-14.17358899,-13.99844852,-13.18120758,-13.3242634,-14.27936342,-8.397130689,-3.472566849 -2608,D161H,-0.095353583,-0.065950842,-0.058164247,-0.024234273,-1.928225329,0.053954759,-0.058767391,-0.131939774,0.062654592,-0.060229229,-0.071672455,-0.063000175,-0.053328318,0.021259421,-0.069727966,-1.600282847,-2.25616781,0.69345813,1.316599517,-12.87713665,-13.967882,-11.9338678,-13.71345004,-10.81879561,-13.95168781,-8.339767128,-3.318978514 -2609,D161K,-0.12650453,-0.072544454,-0.316735638,-2.316746905,-2.460173728,0.095025373,-0.095785419,-0.15722364,-0.082168586,-0.064719543,-0.080369364,-0.178931024,-0.454540251,-1.5971068,-3.036387009,-2.550686264,-2.369661191,1.188794531,0.743321751,-13.23109526,-14.49564706,-13.08944471,-14.46954542,-10.31582945,-13.78500966,-8.284320425,-2.321639482 -2610,D161M,-0.156952801,-0.118727154,-0.09845992,-0.171500113,-1.926115503,0.087543348,-0.115659782,-0.19824582,0.044812985,-0.053757878,-0.18369643,-0.097229581,-0.099690258,-0.10402619,-0.238974035,-1.889201224,-1.963029782,0.983920804,1.315510174,-15.51436799,-15.83515818,-15.97575707,-15.1925275,-13.30160258,-17.2667946,-9.182369939,-5.114383022 -2611,D161L,-0.089750285,-0.06971346,-0.224141808,-1.893329444,-3.35120605,0.051837941,-0.089296739,-0.09020383,0.002524325,-0.021009013,-0.118417907,-0.149845863,-0.298437753,-1.666042222,-2.120616666,-3.041695375,-3.660716724,1.026334181,0.714551904,-13.68521433,-14.11459354,-14.47441222,-13.95612801,-12.00477789,-13.87616,-8.451608366,-2.516541712 -2612,D161N,-0.07002509,-0.00172883,-0.080452993,0.001966741,-0.621962917,0.111207812,-0.008209159,-0.13184102,0.042131012,-0.015790632,0.012332972,-0.019798225,-0.141107761,-0.033083609,0.037017091,-0.662057539,-0.581868295,0.896732779,1.449667508,-8.572680447,-9.59049408,-7.637481316,-9.495830978,-8.082341492,-8.057254372,-7.197342792,-1.746783276 -2613,D161Q,-0.070759951,-0.056316367,-0.050416548,-0.170371534,-1.870180211,0.048214158,-0.026522889,-0.114997012,0.04172875,-0.04031377,-0.072318964,-0.064401974,-0.036431121,-0.09467968,-0.246063388,-1.701471658,-2.038888763,1.363000051,1.379699534,-12.83102828,-15.19735185,-13.13547095,-12.9504473,-11.39873111,-11.4731402,-6.898414785,-2.109933944 -2614,D161P,-0.07721476,-1.553622388,-2.194788319,-2.230308746,-3.45690128,0.052037239,-0.035432784,-0.118996735,-0.022434103,-1.584715869,-1.522528906,-2.061816677,-2.327759961,-1.979390102,-2.481227389,-3.087871526,-3.825931033,-0.131189854,-1.005753369,-14.87375725,-15.91686683,-14.39036547,-15.16599724,-14.22465984,-14.67089685,-9.654606453,-5.400574416 -2615,D161S,-0.083540559,-0.057183398,-0.061549994,-0.036778073,-1.313168235,0.130557325,-0.052596211,-0.114484907,-0.034780964,-0.059310894,-0.055055901,-0.049420908,-0.073679079,-0.035981664,-0.037574481,-1.081416951,-1.544919518,0.819974193,1.363870968,-8.806065321,-11.44112521,-7.571183075,-10.11536168,-7.030923386,-7.871733261,-5.605814856,-2.553518119 -2616,D161R,-0.086011131,-0.061761507,-0.705353715,-2.155316755,-2.503933896,0.081029585,-0.057967638,-0.114054624,-0.04435846,-0.052330189,-0.071192825,-0.499644766,-0.911062663,-1.741197385,-2.569436125,-2.528904756,-2.478963035,1.769566793,0.844186293,-12.72638799,-14.34664201,-11.84157831,-13.79447385,-10.46859388,-13.18065192,-7.816632365,-1.556430911 -2617,D161T,-0.08186665,-0.037084608,-0.014758338,-0.034511641,-1.585055309,0.10174064,-0.04860552,-0.115127779,0.005038923,-0.012081682,-0.062087533,0.010669672,-0.040186348,-0.018839507,-0.050183774,-1.538725693,-1.631384925,0.872682338,1.329733117,-10.18597303,-11.43014977,-11.13449303,-9.781840851,-8.862585098,-9.720796387,-6.79781238,-2.851261144 -2618,D161W,-0.019340629,-0.064226418,-0.496909567,-1.822103169,-2.7815416,0.012014423,0.032899655,-0.071580912,-0.027362966,-0.124803776,-0.003649059,-0.333400295,-0.660418839,-1.830757317,-1.813449021,-2.939238741,-2.623844458,1.510421163,0.756367805,-17.14101957,-17.49109698,-16.38699695,-17.52819489,-16.49462246,-17.80418659,-11.04656685,-7.264617224 -2619,D161V,-0.129734117,-0.054072317,-0.049243682,-0.051189816,-1.579928924,0.060259904,-0.105485557,-0.153982677,-0.018214266,-0.040467631,-0.067677002,-0.03067208,-0.067815284,-0.017584113,-0.084795519,-1.572906912,-1.586950936,0.71045965,1.319131681,-10.94645488,-10.58341835,-11.06602533,-10.48153832,-10.65123735,-11.95005505,-6.788903743,-2.127282258 -2620,D161Y,-0.05521422,-0.078894651,-0.039304037,-0.966789231,-2.4218407,0.037602272,-0.06381173,-0.04661671,-0.006073732,-0.140616843,-0.017172459,-0.068245314,-0.01036276,-0.575644274,-1.357934188,-1.927163747,-2.916517653,1.850426471,1.448434552,-16.31672933,-16.9536083,-17.55546302,-15.32879086,-15.00440263,-16.74138184,-8.463720157,-3.436432182 -2621,R162A,0.013039334,0.013666854,-0.006380363,-0.003183783,-2.052036726,0.710676798,0.018282793,0.007795874,0.029035292,0.00876204,0.018571667,-0.016076111,0.003315386,-0.006572556,0.000204991,-1.874608491,-2.229464961,0.712795762,1.303444692,-13.40647427,-12.78526608,-13.5267414,-15.22016901,-12.69214344,-12.80805142,-7.007269453,-2.67247687 -2622,R162C,-0.070157827,-0.030887902,-0.004550383,-0.008773342,-1.942558976,0.294017175,-0.071852187,-0.068463467,0.037713558,0.030368741,-0.092144544,0.043769992,-0.052870758,0.043641646,-0.06118833,-1.681014132,-2.204103819,0.558241186,1.305932596,-16.71286543,-16.2110555,-16.72165221,-17.46296417,-17.83572593,-15.33292934,-9.714961215,-6.479640252 -2623,R162E,-0.026155304,-0.027690471,0.018052636,-0.682339619,-2.229220485,0.325070612,0.004625586,-0.056936193,0.004001623,-0.031398702,-0.02398224,0.030851749,0.005253522,-0.380706346,-0.983972892,-2.153409611,-2.305031359,1.436542339,1.319962324,-14.47413447,-16.18828601,-14.0148278,-15.10484735,-13.26012266,-13.8025885,-8.150268899,-3.705863138 -2624,R162D,-0.032867459,-0.049416702,-0.030315453,-0.070850244,-1.797269994,0.948436124,-0.012927126,-0.052807791,0.02339357,-0.021328693,-0.07750471,-0.010777568,-0.049853338,-0.068493068,-0.073207419,-1.249650367,-2.344889621,0.892115602,1.354440736,-13.29316224,-14.91927184,-12.23097237,-13.21223911,-12.85721874,-13.24610914,-6.191696796,-3.373588769 -2625,R162G,0.017657807,0.012760522,-0.003496629,-0.013391633,-1.460298623,0.809981254,0.033011084,0.002304529,-0.000111523,0.007741455,0.017779588,-0.013193774,0.006200517,-0.03013575,0.003352485,-1.238914758,-1.681682487,0.693145977,1.335882679,-15.05448282,-14.13933615,-16.15623193,-15.3139855,-16.14182278,-13.52103777,-7.544529116,-3.346563271 -2626,R162F,-0.010716356,0.005011374,-0.164267481,-2.072544665,-2.76348965,0.086467842,0.058080383,-0.079513094,0.042680999,-0.045508541,0.055531288,-0.104509658,-0.224025304,-1.707273961,-2.437815368,-2.349315316,-3.177663983,0.863764761,0.696101757,-17.78978081,-13.83370365,-17.5888504,-17.4662517,-21.53635898,-18.52373933,-8.652674938,-4.447025842 -2627,R162I,-0.036139333,-0.300358296,-2.300576238,-2.205867078,-2.775293039,0.027927164,-0.05733712,-0.014941545,0.086046495,-0.229340229,-0.371376362,-2.279950755,-2.32120172,-2.422461728,-1.989272428,-2.520435039,-3.030151038,0.185996238,-0.419919745,-16.76736429,-15.49182351,-17.73335866,-17.74301726,-16.07133646,-16.79728556,-8.60904314,-4.458766602 -2628,R162H,0.042839562,0.022684594,0.02638014,-0.016996149,-0.454364178,1.064041417,0.056986913,0.02869221,-0.061643496,0.034096613,0.011272574,-0.005561959,0.058322238,-0.03060076,-0.003391537,-0.413989149,-0.494739207,1.146801791,1.683685548,-8.012232256,-7.638493156,-7.145290695,-8.13841629,-10.35576485,-6.783196289,-6.692561968,-2.320008398 -2629,R162K,-0.022047389,0.027426871,-0.022070713,-0.018237895,-1.553189419,0.114107542,-0.014212109,-0.029882668,-0.014294336,0.024698839,0.030154902,0.004345422,-0.048486848,-0.025191607,-0.011284183,-1.530919909,-1.575458928,0.605586321,1.313882773,-12.75921038,-13.62157138,-14.00103527,-12.04714088,-12.87576459,-11.25053979,-8.516844276,-4.278501193 -2630,R162M,0.055510548,0.034168218,0.026430682,-0.675194757,-2.409700729,0.193809325,0.043258549,0.067762547,-0.02366194,0.00485589,0.063480546,-0.050773288,0.103634651,-0.518582831,-0.831806683,-2.07895414,-2.740447318,1.672948852,1.359658812,-16.0001423,-13.50776031,-17.27514378,-17.16194892,-16.62809741,-15.42776106,-8.148495814,-5.105593839 -2631,R162L,-0.016498782,-0.002711181,-0.029340266,-1.467066735,-2.600935808,0.110018353,0.004269526,-0.037267089,0.026042311,0.003388197,-0.008810559,-0.057826632,-0.000853899,-1.2147468,-1.71938667,-2.027678221,-3.174193394,2.457822576,1.645030835,-15.37390706,-13.81648914,-16.53858141,-16.99187341,-14.84177122,-14.68082011,-8.198210749,-5.142809617 -2632,R162N,0.072672941,0.083905291,0.03837183,0.016621897,-0.318084574,1.1137175,0.037385052,0.10796083,0.044287161,0.076755006,0.091055576,0.059341982,0.017401677,0.014248672,0.018995121,-0.243876697,-0.392292451,1.016331749,1.761011297,-13.97357111,-14.85935603,-13.96016421,-13.4612851,-15.45265293,-12.13439729,-7.714029219,-2.21911816 -2633,R162Q,0.048484828,0.056271311,0.066502918,0.000373536,-0.955581138,0.523068075,0.046162983,0.050806672,-0.026851624,0.030533278,0.082009343,0.071573725,0.06143211,0.012528072,-0.011781001,-0.935905007,-0.975257269,0.643579035,1.354795011,-10.4977702,-10.75079803,-11.21688216,-10.59140076,-10.89104184,-9.038728203,-7.557819223,-3.804060528 -2634,R162P,-0.028398487,-1.455384712,-1.8272121,-1.938700903,-2.432689628,0.090456613,0.017893353,-0.074690327,-0.041242007,-1.531898699,-1.378870724,-1.847033163,-1.807391037,-1.767695386,-2.109706419,-2.564638701,-2.300740554,-0.071866542,-0.97614785,-15.42498967,-16.76628132,-15.59979405,-16.29042326,-12.97398383,-15.49446588,-8.319902109,-3.720392844 -2635,R162S,-0.000719945,0.013098363,-0.010862563,-0.027030982,-0.460633359,1.129394537,0.000226049,-0.001665939,-0.004210231,0.027935047,-0.001738321,-0.013147242,-0.008577884,-0.016714365,-0.037347598,-0.381244788,-0.54002193,1.563278209,1.983906726,-13.91110369,-14.34488907,-13.5437494,-15.36910068,-13.64308521,-12.65469411,-6.901898123,-2.658960166 -2636,R162T,-0.052615163,-0.031957021,-0.021453834,-0.031577131,-1.077646983,0.090227991,-0.075330358,-0.029899968,0.005899958,0.03560436,-0.099518401,0.001390903,-0.04429857,0.005121373,-0.068275634,-0.924002264,-1.231291701,0.761670471,1.37192277,-14.19588387,-14.10910554,-13.94850131,-15.59345864,-13.69940262,-13.62895126,-7.791255169,-3.157326825 -2637,R162W,-0.009361967,-0.017632794,-1.308938288,-1.876576085,-3.042912059,0.037447685,0.033261847,-0.051985781,-0.008032719,-0.023586776,-0.011678812,-1.350150702,-1.267725874,-1.969782929,-1.783369241,-2.766726245,-3.319097873,2.651085433,1.138548254,-16.41846195,-16.56449343,-15.56493394,-15.93522244,-19.7206536,-14.30700634,-9.487746595,-6.084533048 -2638,R162V,-0.032957523,0.001723938,-1.201424467,-2.102820185,-3.188958023,0.061281703,-0.008911453,-0.057003592,0.013970781,-0.009716663,0.013164539,-1.12769904,-1.275149893,-1.958184633,-2.247455736,-2.561307922,-3.816608123,2.366014195,0.996304334,-14.71488306,-14.16886832,-16.37949016,-15.90224812,-12.93665727,-14.18715143,-7.610790049,-3.776769819 -2639,R162Y,-0.054955,-0.017161984,-0.627198429,-2.443224197,-2.86213516,0.099495989,-0.036273625,-0.073636375,0.043129197,0.001927318,-0.036251285,-0.376340966,-0.878055891,-2.162304615,-2.724143779,-2.561307922,-3.162962398,1.368765137,0.65209001,-16.37081881,-14.57087296,-17.42459633,-15.58610139,-20.5867116,-13.68581178,-8.289931244,-3.983666061 -2640,W163A,-0.022004943,-0.004331649,-0.03407479,-0.045689653,-0.356231928,-0.043333531,-0.020800868,-0.023209017,0.038732735,-0.021012759,0.012349461,-0.012380216,-0.055769364,-0.056812866,-0.034566439,-0.31722648,-0.395237376,1.52873063,2.053656392,-5.246905757,-6.412155113,-3.918814964,-5.111279091,-5.065495285,-5.726784332,-5.203526917,-2.529995059 -2641,W163C,-0.01488316,-0.020287351,-0.021445094,-0.024422869,-0.266007873,-0.03436324,-0.009480909,-0.020285411,0.044559034,-0.061874056,0.021299354,0.008430591,-0.051320779,-0.05777657,0.008930832,-0.239689621,-0.292326124,1.275254113,1.930625217,-7.303467581,-8.598191864,-6.12808728,-6.065895821,-7.846106689,-7.879056252,-6.819717847,-4.539242748 -2642,W163E,-0.009820251,-0.012109613,-0.008143561,-0.001248281,-0.325154719,-0.011510044,-0.014450605,-0.005189896,0.039222532,0.002419241,-0.026638467,-0.029592444,0.013305322,-0.030908188,0.028411627,-0.266681788,-0.38362765,1.305234445,1.928627581,-5.828521883,-6.783417137,-5.334286186,-5.829899773,-5.680940575,-5.514065742,-6.383517784,-2.409447493 -2643,W163D,0.014823731,0.00625269,0.0192872,-0.01604435,-0.658121798,0.078159003,0.032444023,-0.002796561,0.055799854,0.007437893,0.005067486,0.002468905,0.036105494,-0.013324188,-0.018764511,-0.504981478,-0.811262118,0.86310733,1.487320613,-4.966223427,-6.274083191,-2.741832214,-4.654009727,-6.670378922,-4.49081308,-5.696116073,-0.891508741 -2644,W163G,-0.003295666,-0.007736018,0.0087194,-0.011963573,-0.720388025,0.000903972,-0.006785942,0.000194611,0.019992154,-0.023939266,0.008467231,0.010092004,0.007346796,-0.027694276,0.00376713,-0.581548213,-0.859227837,0.993326375,1.516977071,-5.753455769,-7.066111786,-4.451125275,-5.617607063,-5.544435837,-6.087998886,-5.672533386,-0.674048236 -2645,W163F,-0.02609923,-0.049511665,-0.043193453,-0.005615639,-0.2044242,-0.044948041,-0.044180152,-0.008018307,0.012592403,-0.069898301,-0.029125028,-0.056401127,-0.029985779,-0.050391678,0.039160401,-0.161255924,-0.247592476,1.33500888,2.092666864,-3.832996361,-5.08917205,-2.953329224,-3.087899834,-3.566759537,-4.467821159,-3.507711675,-1.692328198 -2646,W163I,0.055903279,0.031102247,0.026509827,-0.018841289,-0.058474829,-0.018283128,0.059773815,0.052032742,0.003774251,-0.013445883,0.075650377,-0.007776873,0.060796526,-0.066949826,0.029267248,-0.13439632,0.017446662,1.494226484,2.318899517,-3.313435425,-4.644261932,-1.841537735,-2.138367195,-4.462929077,-3.480081184,-3.561412319,-0.858343768 -2647,W163H,0.043102825,0.015131977,-0.021810553,-0.003039665,-0.3439385,-0.039147404,0.070472466,0.015733183,0.034037449,0.029690022,0.000573932,-0.07903375,0.035412645,-0.028831303,0.022751974,-0.340479149,-0.34739785,1.478403149,1.961890967,-4.071987851,-5.530912796,-3.886641434,-3.922721878,-3.605863464,-3.413799683,-4.352410154,-2.792137276 -2648,W163K,0.003664092,-0.025659179,-0.006395678,-0.028906711,-0.280734493,-0.03393756,0.015744025,-0.008415841,0.020523053,-0.024449989,-0.026868368,-0.023958209,0.011166853,-0.075901186,0.018087765,-0.25048784,-0.310981145,1.666082389,2.228923006,-3.718199545,-5.158211548,-2.37640081,-3.374036812,-4.417221596,-3.265126961,-4.45301294,-0.047543186 -2649,W163M,-0.027461381,0.014279646,0.015744117,0.028577104,-0.069283073,-0.049284425,-0.040138928,-0.014783833,0.02579427,0.045938561,-0.017379269,0.022970251,0.008517983,0.03119251,0.025961698,-0.051278382,-0.087287764,1.201765173,2.357535951,-4.51601823,-5.929462532,-3.472301804,-3.271124062,-5.766464394,-4.140738358,-4.753816644,-1.972144633 -2650,W163L,-0.005738166,-0.017272036,-0.010926389,-0.019421487,-0.240498541,-0.065915422,-0.00222784,-0.009248491,0.026852223,-0.031701649,-0.002842423,-0.023952078,0.002099301,-0.03093215,-0.007910824,-0.219883572,-0.261113509,1.298661257,1.981206238,-4.041255077,-5.426585693,-2.683202675,-3.356630989,-5.819443794,-2.920412231,-4.422816616,-0.963830443 -2651,W163N,-0.035596295,-0.000848432,-0.01498105,-0.000041,-0.209431811,-0.096141014,-0.044082484,-0.027110105,0.028833241,0.003006839,-0.004703702,-0.008604131,-0.021357968,-0.011583825,0.011501892,-0.196830007,-0.222033614,1.366181058,2.096238498,-2.741142307,-3.919673538,-1.696096794,-2.140633743,-3.26898317,-2.680324287,-3.751011301,-0.622034493 -2652,W163Q,0.028755979,0.013221041,0.018205583,0.003915841,-0.355667128,-0.075654338,0.04726543,0.010246527,0.039989952,0.031741962,-0.00529988,0.004613625,0.03179754,-0.02537953,0.033211211,-0.278534614,-0.432799641,1.559254147,2.155940437,-4.636570882,-5.055730804,-3.836182777,-5.228609634,-4.728254456,-4.334076736,-4.643901428,-2.981449477 -2653,W163P,0.009120472,-0.02635468,-0.004832039,-0.013349479,-0.605318946,-0.0579525,0.007521721,0.010719222,0.027258865,-0.027033165,-0.025676194,-0.038973999,0.029309921,-0.042592812,0.015893855,-0.487806109,-0.722831782,1.311143135,1.726085232,-4.895965512,-6.14794355,-3.84308828,-4.648128693,-5.622339409,-4.218327629,-4.79332921,-1.261463893 -2654,W163S,0.036677386,-0.001639648,0.007884911,-0.003478837,-0.340141466,-0.048247998,0.048088381,0.02526639,-0.006405619,-0.004025397,0.000746101,0.006350442,0.00941938,-0.037140276,0.030182602,-0.284068609,-0.396214322,1.799679523,2.299866525,-5.467296619,-6.285222679,-3.731226402,-5.012857521,-6.345606651,-5.961569839,-5.502603165,-1.431180778 -2655,W163R,0.005414422,0.005021383,0.01892314,0.003957809,-0.275885436,-0.043200888,-0.003029639,0.013858483,0.022698394,-0.009082549,0.019125315,0.020917291,0.016928989,-0.005311059,0.013226676,-0.235232763,-0.316538108,1.589341757,2.214786468,-2.203317815,-3.059701111,-1.305087616,-1.933620728,-3.046082634,-1.672096985,-3.799333137,-0.455727836 -2656,W163T,0.026030698,-0.00950633,0.018414281,-0.008092335,-0.192326549,-0.042025363,0.040276062,0.011785334,0.044459107,-0.018191881,-0.000820779,0.015689248,0.021139314,-0.037361264,0.021176595,-0.163657854,-0.220995244,1.399970171,2.161120397,-2.860510988,-3.299626335,-1.190045647,-2.176510834,-4.291277802,-3.345094322,-3.367915352,0.035773602 -2657,W163V,-0.012845111,0.003346084,-0.03357242,-0.022842559,-0.158162042,-0.033819977,-0.013786516,-0.011903705,0.028684072,-0.006799105,0.013491272,-0.024645418,-0.042499421,-0.031542957,-0.014142161,-0.140497361,-0.175826723,1.487756609,2.299630945,-4.437708655,-5.883965004,-3.386404114,-3.747049347,-5.040678932,-4.130445877,-4.502405871,-1.985671467 -2658,W163Y,0.02722189,-0.003046494,0.01867395,0.005171987,-0.110791918,-0.089931732,0.042378158,0.012065621,0.033166042,0.01120954,-0.017302528,0.019897462,0.017450438,0.025115978,-0.014772005,-0.067840142,-0.153743693,1.233653721,2.383984478,-2.830430898,-3.969158829,-2.220497475,-2.699337395,-2.323745209,-2.939415581,-3.387458592,-0.467958473 -2659,E164A,0.060081528,-1.612476742,-2.264349123,-2.192751981,-3.221815216,-0.043044177,0.068283184,0.051879872,-0.086693326,-1.669124241,-1.555829242,-2.347685213,-2.181013032,-2.155222551,-2.23028141,-3.090713738,-3.352916694,-0.163810327,-1.077986141,-9.986277783,-9.777449875,-14.84284362,-9.440222473,-8.978788147,-6.892084801,-6.736497348,-4.056130563 -2660,E164C,0.042852698,-1.8898592,-2.475895522,-2.272275165,-3.04428599,-0.12652358,0.06673181,0.018973586,-0.075213509,-1.937131955,-1.842586445,-1.97887083,-2.972920213,-2.154384953,-2.390165377,-2.721899354,-3.366672626,-0.420073284,-1.137605922,-14.83487093,-15.15025117,-19.8218864,-13.92187298,-14.22212894,-11.05821514,-9.509415575,-5.173556779 -2661,E164D,-0.007808159,-0.862277112,-1.436456297,-1.866212101,-2.074786308,0.140039246,0.064298429,-0.079914747,0.012151186,-0.873595235,-0.850958988,-1.408249632,-1.464662961,-1.935946273,-1.796477929,-1.929429406,-2.220143209,4.265619212,2.51794917,-9.415001616,-9.728662399,-12.64203629,-7.78894162,-8.804949509,-8.110418266,-7.339123221,-3.612970264 -2662,E164G,-0.01671895,-1.496906577,-2.046241694,-2.318558303,-3.05785632,0.217396629,0.018817143,-0.052255042,-0.139296548,-1.588389565,-1.405423589,-2.001965646,-2.090517741,-2.142717663,-2.494398943,-2.670360552,-3.445352087,0.644588947,-0.925734447,-13.25631682,-12.53022195,-14.93158228,-14.52949016,-12.15780497,-12.13248476,-7.68726208,-4.303261268 -2663,E164F,0.047813307,-1.671370539,-2.073418468,-2.553786504,-2.825797328,0.671854585,0.107233863,-0.01160725,-0.193349702,-1.586414176,-1.756326902,-2.4063043,-1.740532635,-2.104697169,-3.002875838,-2.371181574,-3.280413082,0.049409217,-1.09447395,-14.74076965,-16.14969238,-21.10988087,-13.03793656,-12.92461571,-10.48172276,-7.301922069,-3.375271514 -2664,E164I,0.045687699,-1.75360409,-2.388095418,-2.684475062,-2.868440257,-0.028313283,0.063659295,0.027716102,-0.096565617,-1.968267364,-1.538940816,-2.010006239,-2.766184597,-2.486550358,-2.882399765,-2.576943504,-3.159937009,-0.951815022,-1.149341479,-16.12982331,-16.01400848,-23.66417783,-14.72477146,-14.92762304,-11.31853572,-7.202635244,-2.84127593 -2665,E164H,-0.017968573,-1.495373582,-2.037760335,-2.899306864,-3.233787056,0.319599769,0.028954011,-0.064891156,-0.071897395,-1.60822971,-1.382517453,-2.17284733,-1.90267334,-2.524452713,-3.274161014,-2.915875854,-3.551698258,-0.171126709,-1.027088092,-12.99250601,-13.59337513,-18.60009975,-10.53248678,-13.81210065,-8.424467766,-7.643004972,-5.665809293 -2666,E164K,0.077648848,-0.964907461,-1.804851282,-2.709972898,-2.893938093,0.261358198,0.136223798,0.019073897,-0.052096634,-1.192838972,-0.73697595,-1.933547851,-1.676154713,-2.586183229,-2.833762566,-2.676576375,-3.11129981,0.637961867,-0.692884232,-12.12417852,-14.08195161,-15.0365836,-11.27590714,-10.23982819,-9.986622047,-7.924268873,-4.671260829 -2667,E164M,-0.070613453,-1.76490504,-2.454504108,-2.838929381,-2.872379578,-0.05941116,-0.061668968,-0.079557937,-0.148565211,-2.076500407,-1.453309672,-2.419269278,-2.489738937,-2.594783401,-3.08307536,-2.384146551,-3.360612604,-0.523940497,-1.198749995,-16.28372884,-16.37340189,-23.49623007,-17.28861965,-13.46835154,-10.79204105,-7.841701524,-1.649575053 -2668,E164L,0.033686007,-1.640660937,-2.084481891,-2.199711708,-3.357557094,-0.07898183,0.076089691,-0.008717677,-0.109367785,-1.722076778,-1.559245095,-2.219747608,-1.949216174,-2.094231735,-2.305191681,-2.853631662,-3.861482526,-0.0738483,-1.077391623,-16.5373069,-15.47368821,-25.50088382,-16.15609193,-15.90736565,-9.648504875,-7.76554407,-1.825243809 -2669,E164N,0.070888483,-1.519066213,-2.054373714,-2.549723362,-2.321734186,-0.015868095,0.100831856,0.040945109,-0.183928833,-1.843146495,-1.19498593,-1.583855374,-2.524892053,-1.981218247,-3.118228476,-2.247702652,-2.39576572,-0.196800474,-1.097205403,-13.77679116,-13.08011882,-20.64650765,-11.46499214,-13.78201531,-9.910321892,-8.374249392,-5.6974776 -2670,E164Q,-0.023614264,-1.579139042,-2.607478655,-2.753343301,-2.937308496,0.081904883,0.008414102,-0.055642629,-0.171909002,-1.703886347,-1.454391737,-2.347685213,-2.867272096,-2.523199337,-2.983487264,-2.613592483,-3.261024508,0.028323948,-1.114274362,-10.36497338,-10.38402042,-14.54017455,-10.09036394,-8.302261192,-8.508046783,-8.209619257,-4.620959777 -2671,E164P,0.013400888,-1.594031721,-2.05750879,-2.298539285,-3.133019478,0.779437498,0.013449474,0.013352301,-0.135692506,-1.65230214,-1.535761302,-2.244948484,-1.870069096,-2.374705116,-2.222373453,-3.164068267,-3.101970688,0.129210937,-1.063470648,-13.99691298,-13.26590295,-20.714085,-13.18403093,-11.41228649,-11.40825954,-7.080408719,-3.991932528 -2672,E164S,0.07998695,-1.51626711,-2.03562332,-2.570563591,-3.018665674,-0.029009699,0.089032031,0.070941869,-0.127538086,-1.556707249,-1.47582697,-2.162717554,-1.908529085,-2.162140418,-2.978986763,-2.604716082,-3.432615266,0.160209508,-1.008871423,-11.28197355,-11.86368515,-14.71403962,-10.76322996,-10.61644279,-8.452470222,-7.489372744,-4.554672735 -2673,E164R,0.024984801,-1.575212651,-2.063286221,-2.367241537,-3.21360509,0.25047407,0.061539736,-0.011570134,-0.048808402,-1.669090768,-1.481334534,-2.108769651,-2.01780279,-2.170340423,-2.56414265,-2.77261693,-3.65459325,-0.233838064,-1.06432715,-12.85866729,-16.97799489,-17.48598087,-11.89997205,-10.89856807,-7.030820541,-7.504945356,-3.74604217 -2674,E164T,0.010001866,-1.610440827,-1.859895778,-2.660752843,-2.932763667,-0.001658881,0.025253742,-0.00525001,-0.100629596,-1.695436772,-1.525444882,-1.971258852,-1.748532703,-2.389811025,-2.931694661,-2.781234166,-3.084293168,-0.146316878,-1.083531939,-12.77417935,-12.48618042,-16.62658763,-12.8216103,-12.2880568,-9.648461594,-7.364157478,-2.591350626 -2675,E164W,0.019793274,-1.743472752,-1.94107118,-2.089505645,-3.386125481,0.38113443,0.05830954,-0.018722993,-0.124849278,-1.730658067,-1.756287437,-2.114819623,-1.767322736,-2.086213763,-2.092797526,-3.079696896,-3.692554065,-0.079235929,-1.096493081,-16.60174596,-16.59210052,-24.01899975,-14.6359811,-15.18935376,-12.57229465,-9.281906954,-6.907244504 -2676,E164V,-0.000619346,-1.63607516,-2.370896214,-2.677870507,-2.972760077,0.027243369,0.032563103,-0.033801794,-0.093644343,-1.751847366,-1.520302954,-2.316464986,-2.425327441,-2.668070369,-2.687670645,-2.758463515,-3.187056638,-0.320547108,-1.0962405,-15.05635287,-15.98477374,-22.33514816,-15.28839175,-13.15785397,-8.515596741,-7.401599207,-2.541422135 -2677,E164Y,0.03419084,0.02249866,-0.250997542,-2.16514141,-2.888697228,0.38077883,0.044170005,0.024211675,-0.080535508,-0.018462261,0.06345958,-0.401525726,-0.100469358,-1.957251092,-2.373031728,-2.348674233,-3.428720222,1.509662845,0.727258264,-13.05504209,-12.47342389,-15.85017612,-12.24386271,-13.67717688,-11.03057085,-7.910881038,-4.914496409 -2678,P165A,-0.016733368,0.007880625,-0.034554958,-0.043266222,-1.173297695,0.034138604,0.009538584,-0.04300532,-0.062866577,0.002791609,0.01296964,-0.043286331,-0.025823584,-0.04922396,-0.037308484,-1.074569156,-1.272026234,0.788983064,1.360357597,-5.439867134,-5.34206955,-6.32000222,-4.779540894,-5.812777702,-4.944945305,-6.015881912,-1.997706994 -2679,P165C,-0.027506984,-0.005332266,0.005881785,-0.018828128,-1.21695688,0.119341878,-0.015400974,-0.039612993,-0.049711029,-0.020762888,0.010098356,-0.031627853,0.043391423,-0.04121098,0.003554724,-0.995532811,-1.438380949,0.877315521,1.38499411,-10.35793833,-10.29139707,-10.8469542,-9.935764282,-10.25413562,-10.46144045,-8.575837471,-6.433138002 -2680,P165E,-0.050869929,-0.068533198,-0.034488838,-0.013063191,-1.695484262,0.062438291,-0.049110449,-0.052629408,-0.152343413,-0.014385442,-0.122680954,-0.045382689,-0.023594987,-0.022493079,-0.003633303,-1.599415826,-1.791552697,0.592780347,1.309902125,-6.655948991,-5.554859108,-6.381761498,-6.417485451,-8.71442318,-6.211215721,-6.028212778,-1.389311094 -2681,P165D,-0.025071543,0.002011079,0.045051231,-0.013742967,-1.556104221,0.096454195,-0.048090737,-0.002052349,-0.043322188,0.044492373,-0.040470215,0.065763029,0.024339432,-0.010674099,-0.016811835,-1.430204906,-1.682003535,0.81676416,1.333682387,-8.603315869,-7.89198024,-9.719175156,-7.822255409,-9.803118416,-7.780050125,-6.842423371,-2.484471346 -2682,P165G,-0.00819141,-0.0000622,0.020981296,-0.017634149,-1.984731056,0.511929887,-0.014370119,-0.0020127,-0.024571737,-0.010564631,0.010440258,0.013827534,0.028135057,-0.019376455,-0.015891843,-1.612710189,-2.356751922,0.821199664,1.323318012,-6.557051443,-5.797379967,-7.371419159,-5.583146393,-7.423402077,-6.609909622,-4.389005381,-2.33455074 -2683,P165F,-0.01085904,0.019954104,-0.015868725,-0.406435173,-2.257957,0.010724588,0.00905794,-0.030776019,0.002236849,0.035793591,0.004114617,-0.012309196,-0.019428253,-0.334958944,-0.477911401,-2.127186866,-2.388727133,1.423129076,1.320101552,-10.49646352,-11.37263591,-11.40585867,-10.29292464,-9.39954377,-10.01135462,-7.016608565,-3.723470471 -2684,P165I,-0.083056154,-0.097487041,-0.065830806,-0.026895759,-0.527164155,0.087868882,-0.065145226,-0.100967081,-0.121657413,-0.101440838,-0.093533243,-0.055150991,-0.076510621,-0.077780985,0.023989467,-0.48736758,-0.566960729,1.483369398,1.833297393,-5.878281656,-7.265974655,-5.241792908,-5.763110428,-5.142780548,-5.977749741,-5.399850107,-3.383961555 -2685,P165H,-0.028253211,0.074433425,0.037302612,-0.003344773,-1.577464349,0.06861828,-0.027767151,-0.028739271,-0.085304331,0.10366511,0.045201739,0.063479522,0.011125702,0.037103376,-0.043792921,-1.687485874,-1.467442823,0.550480827,1.311128903,-11.30406255,-10.45648767,-12.17027256,-10.72555392,-11.82903829,-11.33896029,-6.419651294,-4.209086751 -2686,P165K,-0.077917685,0.01561813,0.048688664,-0.023009987,-1.478979037,0.087393433,-0.080474196,-0.075361173,-0.046868329,0.04081352,-0.009577261,0.06943408,0.027943248,-0.057194842,0.011174869,-1.287357979,-1.670600095,0.872244414,1.35109225,-7.859878688,-7.521869095,-8.293712059,-7.52424176,-8.017999496,-7.94157103,-6.1835376,-2.838569621 -2687,P165M,-0.06203848,0.032466781,-0.016022998,-0.01479749,-1.40629147,0.064640505,-0.056152818,-0.067924141,-0.017893304,0.093601063,-0.028667501,0.027576098,-0.059622093,-0.005336723,-0.024258257,-0.926049954,-1.886532986,0.705429432,1.362729995,-7.033396741,-8.282557938,-7.707186432,-6.916445869,-6.092704773,-6.168088692,-5.743922281,-1.23292792 -2688,P165L,-0.052139845,-0.030492476,-0.004881636,-0.0492441,-0.353187675,0.077862419,-0.030475515,-0.073804174,-0.037516668,-0.017925639,-0.043059312,-0.011190511,0.00142724,-0.069927285,-0.028560914,-0.330801969,-0.37557338,1.639272118,2.106430527,-5.303714005,-5.911280426,-5.80230069,-5.918609108,-3.99254702,-4.893832779,-4.59204158,-2.658099212 -2689,P165N,-0.101002375,-0.047014558,-0.050951411,-0.029849685,-0.771029889,0.123933569,-0.083691858,-0.118312891,-0.093427861,0.002174404,-0.096203519,0.000890953,-0.102793775,-0.014487238,-0.045212132,-0.696233183,-0.845826595,0.898812902,1.44151548,-9.085535353,-8.259350449,-8.807022636,-9.00291597,-10.35720254,-9.001185173,-6.809225285,-4.081631892 -2690,P165Q,-0.049024242,-0.032043953,-0.016391274,-0.035589283,-1.401130168,0.118825953,-0.026089453,-0.07195903,0.01105237,-0.055051031,-0.009036875,-0.04377054,0.010987992,-0.088565477,0.017386911,-1.400062259,-1.402198076,0.877811794,1.34188831,-7.585381651,-6.856364731,-7.298057434,-7.996603378,-8.200913101,-7.574969612,-5.935129142,-3.206737011 -2691,P165S,-0.025469443,-0.001371008,-0.014335531,-0.022500626,-1.27638993,0.096454717,-0.015835167,-0.035103719,-0.072837454,0.007983579,-0.010725595,-0.025443989,-0.003227073,-0.028796255,-0.016204997,-1.052852307,-1.499927553,0.734930165,1.355711725,-6.075066383,-5.829662537,-6.144133148,-5.577418823,-6.951619293,-5.872498116,-5.761526514,-3.420295173 -2692,P165R,-0.048184529,-0.001356164,-0.031512507,-0.02700193,-1.540979088,0.093436315,-0.034464369,-0.061904688,-0.075911142,-0.005726847,0.003014519,-0.036748525,-0.026276489,-0.033197566,-0.020806294,-1.490084126,-1.59187405,0.87453776,1.336057892,-8.215258452,-8.510146393,-6.630752304,-8.631724472,-8.76505162,-8.53861747,-6.050950092,-1.666131033 -2693,P165T,0.005106602,-0.011358969,0.011091829,-0.052929989,-0.07192525,0.188851337,0.001738694,0.008474509,0.015913881,-0.039608596,0.016890659,-0.011741702,0.03392536,-0.069964177,-0.0358958,-0.067439057,-0.076411442,1.339477404,2.382976248,-0.739109456,-1.459614563,-0.833903107,-0.039168251,-0.671236214,-0.691625145,-0.483668843,-1.124361004 -2694,P165W,-0.060405824,-0.035290598,0.000729109,-1.033370532,-2.673980819,0.10259163,-0.038408606,-0.082403041,-0.052964187,-0.037211011,-0.033370184,0.018639026,-0.017180808,-0.90585557,-1.160885493,-2.25562861,-3.092333027,1.944259419,1.355310934,-11.3329848,-11.51044146,-11.86488109,-11.13626993,-10.78120815,-11.37212335,-7.984547832,-5.758762842 -2695,P165V,0.035725667,-0.016343426,0.021251806,-0.005679023,-0.337033628,0.122884747,0.039732766,0.031718567,-0.032393623,-0.031516981,-0.00116987,-0.004236597,0.046740208,-0.057212106,0.045854061,-0.328455505,-0.34561175,1.388219168,1.906566134,-5.286228102,-6.600841461,-4.566267242,-5.57330162,-4.637094635,-5.053635551,-4.763265909,-3.452250285 -2696,P165Y,-0.05969833,-0.010500713,-0.021927772,-0.2657837,-2.125045058,0.059893316,-0.084765516,-0.034631144,-0.021487485,0.001063511,-0.022064936,-0.038038031,-0.005817513,-0.174348417,-0.357218983,-1.83168232,-2.418407796,1.182857733,1.336381752,-11.43221446,-11.8996529,-12.47692651,-10.72964124,-10.12848338,-11.92636829,-6.538755134,-4.065942387 -2697,E166A,0.028897534,0.053025133,0.027068808,0.015776523,-0.011919645,-0.039928032,0.022350953,0.035444115,0.01660418,0.058270713,0.047779553,0.025041817,0.029095798,0.020240909,0.011312137,-0.010822329,-0.013016961,1.200270332,2.547443944,-1.2554742,-1.019653687,-1.175729828,-1.389951202,-2.28187011,-0.410166176,-1.752630262,-1.177230575 -2698,E166C,-0.045742172,0.015361678,0.00329139,-0.017483942,-0.058989229,0.042248658,-0.062503449,-0.028980894,0.008122436,0.058928221,-0.028204865,0.04375141,-0.03716863,0.000474356,-0.035442239,-0.02716621,-0.090812248,1.266356399,2.540481288,-7.867562567,-8.238912064,-6.461035461,-8.170910088,-8.914844414,-7.552110809,-9.087975263,-9.120583477 -2699,E166D,0.050109756,0.053185069,0.025114711,0.03902202,0.005592246,0.010924678,0.033129529,0.067089982,0.048700721,0.049754575,0.056615563,0.003071688,0.047157734,0.061157715,0.016886325,-0.023748325,0.034932817,1.247305402,2.690587958,-1.558416658,-1.614027199,-1.066528488,-2.273651215,-1.899801384,-0.938075005,-2.629625572,0.104510265 -2700,E166G,-0.000124314,0.048933151,0.010628576,0.012021878,-0.060012719,0.02457081,-0.009734024,0.009485396,0.030882696,0.073761315,0.024104987,0.031874634,-0.010617482,0.055789271,-0.031745515,-0.045158023,-0.074867414,1.359022036,2.750051038,-3.504978767,-3.954187805,-2.612458504,-3.965504387,-4.609133415,-2.383609726,-4.198108028,-1.85002317 -2701,E166F,-0.030926282,-0.006136848,-0.057421626,-0.012560358,-0.047233269,0.004426191,-0.023937201,-0.037915363,0.057084392,0.047670141,-0.059943836,-0.048494753,-0.066348498,0.009541683,-0.034662398,-0.021271756,-0.073194781,1.313536315,2.535703096,-5.32225546,-6.378616882,-3.845511887,-5.855955833,-5.809816452,-4.721376244,-5.408989424,-4.146250001 -2702,E166I,0.068212821,0.009041805,0.073317241,-0.021082512,-0.122481057,0.017751235,0.062237392,0.074188249,0.099266386,0.012979629,0.00510398,0.062207407,0.084427074,-0.007386076,-0.034778948,-0.141486936,-0.103475177,1.425873483,2.277985184,-6.743083908,-7.144859421,-4.676307098,-6.842818619,-7.413378426,-7.638055977,-5.867705283,-3.635250767 -2703,E166H,0.064472407,0.051440066,0.040566516,0.027583492,0.058182299,0.039333807,0.05801755,0.070927263,0.018967839,0.091067262,0.01181287,0.057981532,0.0231515,0.058973315,-0.003806331,0.05307161,0.063292988,0.982773914,2.721089062,-4.396125407,-3.478350189,-2.777450661,-5.111515839,-5.914437775,-4.698872574,-5.08801418,-3.227800228 -2704,E166K,0.020863923,0.020961004,0.014419564,0.02774677,-0.058571476,0.03636585,0.028522177,0.013205668,0.046108764,0.029813108,0.0121089,0.015182769,0.013656359,0.036830009,0.01866353,-0.037009349,-0.080133602,1.226266326,2.521170292,-4.167360892,-5.263708496,-2.743782036,-4.016729233,-4.565670715,-4.246913979,-4.75153837,-2.923080742 -2705,E166M,-0.035666653,0.036783627,0.049154719,0.010634657,0.003712481,0.016741465,-0.059572027,-0.011761278,0.026132808,0.10371128,-0.030144027,0.078167087,0.020142351,0.033558524,-0.012289211,0.040133707,-0.032708745,1.110198041,2.849730404,-5.111784628,-5.185610504,-3.598308853,-5.524823242,-6.152654839,-5.097525703,-5.347416013,-3.727191659 -2706,E166L,0.01323957,0.038615914,0.014330124,-0.003781048,-0.040056983,-0.049241371,0.007776205,0.018702934,0.022666707,0.06609844,0.011133388,0.016738469,0.011921779,0.015639879,-0.023201974,-0.040721501,-0.039392464,1.217689593,2.419237274,-4.712764226,-4.465135078,-2.748326004,-4.867181625,-6.12572052,-5.357457901,-4.345703609,-2.849777432 -2707,E166N,-0.042662336,0.015499862,-0.005370071,-0.004348513,-0.069317183,0.012366294,-0.035269206,-0.050055465,-0.0031013,0.05670018,-0.025700456,0.077285521,-0.088025663,0.069957832,-0.078654858,-0.020284215,-0.11835015,1.16455779,2.53594446,-4.928578004,-5.743959,-3.646906555,-5.044894783,-5.570473991,-4.636655693,-5.389385582,-3.809826025 -2708,E166Q,-0.015855998,0.026265542,-0.016725943,-0.007830972,-0.021115558,-0.022885249,-0.037881654,0.006169659,0.045396228,0.04722965,0.005301433,-0.010249882,-0.023202004,0.003709939,-0.019371882,-0.034116221,-0.008114895,1.326265902,2.462686796,-3.392686113,-3.447271423,-2.030164383,-4.01893441,-3.603532982,-3.863527367,-4.681928339,-1.978431199 -2709,E166P,-0.032698756,0.01452947,-0.006200669,-0.051852343,-1.836023503,0.032343397,-0.04542116,-0.019976352,0.011147289,0.045179547,-0.016120607,-0.009107444,-0.003293893,-0.020813028,-0.082891657,-1.672281006,-1.999766,0.62787574,1.307767011,-6.476953256,-6.499234138,-4.038883476,-7.15712458,-8.492500786,-6.1970233,-6.848003815,-3.881706204 -2710,E166S,0.020317328,0.022279259,0.00918526,0.008188422,-0.030948467,0.043227695,0.016488581,0.024146074,0.00110348,0.05588664,-0.011328122,0.041843775,-0.023473256,0.031312917,-0.014936074,-0.033723372,-0.028173561,1.152808179,2.428002183,-2.496074397,-2.228454887,-1.641732979,-2.810878426,-3.466341858,-2.332963837,-3.016855466,-2.333488209 -2711,E166R,0.008139333,0.027227097,0.010429474,0.008978958,-0.072704092,0.027905789,0.011953915,0.004324751,0.011267769,0.059387226,-0.004933033,0.019658111,0.001200837,0.03211004,-0.014152125,-0.088948078,-0.056460105,1.173860591,2.245231727,-5.364735696,-5.849258598,-2.738401619,-6.105006691,-6.537979118,-5.593032455,-5.617802914,-2.582419616 -2712,E166T,0.012194587,0.027449286,0.01491156,-0.006641364,-0.043164957,0.058641426,-0.000216746,0.024605919,0.029566947,0.018362755,0.036535816,0.014457192,0.015365927,0.006600541,-0.019883269,-0.072598401,-0.013731512,1.204548321,2.313700915,-1.954629581,-1.848165405,-1.540262451,-1.997500145,-2.860038399,-1.527181503,-3.244986699,-1.762482719 -2713,E166W,0.039062323,0.044336457,0.0319567,0.034112628,-0.022417454,-0.006991553,0.025514585,0.05261006,0.061514633,0.049587385,0.039085528,0.030020904,0.033892496,0.018545402,0.049679853,-0.047856855,0.003021947,1.370318051,2.487426371,-7.692036961,-8.595013855,-5.073739388,-8.598346634,-8.509689446,-7.683395485,-7.139362656,-4.803275952 -2714,E166V,-0.0469483,-0.018338363,-0.014486171,-0.020546363,-0.109649546,-0.003023596,-0.061429827,-0.032466773,-0.003226234,0.009109746,-0.045786472,0.017153182,-0.046125523,0.00140831,-0.042501036,-0.128059179,-0.091239913,1.272030866,2.155326384,-5.314016086,-5.894460182,-3.485250671,-5.667102036,-6.490270821,-5.032996719,-5.619667404,-2.977658273 -2715,E166Y,0.054499778,0.069139822,0.030585809,0.037582078,0.067210162,0.029815854,0.054664015,0.054335541,0.028332491,0.076827045,0.061452599,0.030959001,0.030212616,0.048351488,0.026812668,0.02053526,0.113885063,1.042526455,2.77922482,-5.070955985,-4.751033249,-4.00399115,-5.827057098,-5.28512278,-5.487575645,-5.062333913,-4.486062198 -2716,L167A,0.02375616,0.023421773,-0.009327488,0.01719356,-0.999179737,0.10636589,0.015547892,0.031964428,,0.003580354,0.043263191,-0.03930123,0.020646254,-0.005961933,0.040349053,-0.903011196,-1.095348277,0.933007633,1.409695524,-8.948857176,-15.60677046,-8.645514999,-6.623279076,-8.636686043,-5.232035301,-5.87807309,-2.434138098 -2717,L167C,-0.009622642,0.009378968,0.009273216,0.019074902,-0.017578104,0.324937707,-0.026464725,0.007219442,,0.008120038,0.010637897,0.01423978,0.004306651,0.035158349,0.002991455,0.024157898,-0.059314105,1.181087765,2.734850613,-12.66186066,-17.85498299,-11.60480917,-12.03028181,-11.92117337,-9.898055939,-9.230988578,-6.433781748 -2718,L167E,-0.02351057,-0.010870129,-1.7664628,-2.019669632,-2.415411747,0.102810013,-0.003418636,-0.043602504,,0.02053398,-0.042274238,-1.768762994,-1.764162606,-1.822186766,-2.217152497,-2.547997273,-2.282826221,3.366757628,1.680881465,-12.94675976,-19.18140831,-12.54914303,-10.5761946,-13.02590199,-9.401150856,-8.100678089,-4.33252842 -2719,L167D,-0.035346381,-0.01042663,-1.906036512,-2.272300482,-3.000815722,0.129185939,-0.032638352,-0.03805441,,0.04193836,-0.062791619,-1.803261971,-2.008811052,-2.1955043,-2.349096663,-2.921314807,-3.080316636,0.37461203,-0.043607626,-14.98490002,-21.2457933,-14.9710472,-12.81838144,-13.5105023,-12.37877585,-9.886197986,-6.827714681 -2720,L167G,-0.037925805,-0.000473517,-0.027186255,-1.818960448,-2.585553084,0.120777308,-0.022551944,-0.053299666,,0.003677527,-0.004624561,-0.054673642,0.000301132,-1.783542452,-1.854378444,-2.509352959,-2.661753208,0.762818376,0.684895182,-13.31886579,-19.06172137,-13.04595895,-11.38772196,-13.09084485,-10.00808182,-7.980194748,-4.051554728 -2721,L167F,-0.063173033,-0.015112259,-0.07621069,-1.981400465,-2.141151773,0.035127701,-0.045568079,-0.080777987,,-0.032957972,0.002733455,-0.031222863,-0.121198517,-1.925208921,-2.037592009,-2.128140683,-2.154162863,0.656412805,0.665356462,-10.75441684,-13.47082108,-9.614051613,-10.12024406,-10.12793063,-10.4390368,-6.878747225,-2.069342473 -2722,L167I,0.05100575,-0.003479664,-0.000330755,0.007430139,-0.034959373,0.065152378,0.059176502,0.042834997,,-0.066577334,0.059618006,-0.050664825,0.050003315,0.007061854,0.007798423,-0.022589626,-0.04732912,1.235117378,2.449877744,-7.061143478,-7.648991348,-8.380282127,-5.950976273,-7.898425507,-5.427042137,-6.633884124,-2.867073744 -2723,L167H,-0.034469499,-0.000867085,-1.054665709,-1.992364996,-2.551329907,0.093240387,-0.037262444,-0.031676553,,-0.045055579,0.04332141,-1.223344725,-0.885986693,-2.076317892,-1.9084121,-2.552250926,-2.550408888,2.409891747,0.997950092,-16.64363116,-18.836947,-15.23906696,-18.80386088,-16.22647098,-14.11180997,-9.182611812,-5.737775406 -2724,L167K,-0.016945994,-0.435020452,-2.028211601,-2.207789663,-3.034945182,0.109958101,-0.010870506,-0.023021481,,-0.362738828,-0.507302075,-2.379603321,-1.676819881,-2.294724396,-2.120854929,-2.895596166,-3.174294197,0.288556437,-0.463194356,-13.62551021,-18.38776946,-13.93817324,-14.09304472,-11.41351299,-10.29505064,-8.870904919,-5.204226364 -2725,L167M,0.043775427,0.009471524,0.016531342,0.022821049,-0.095031072,0.212735612,0.063928759,0.023622094,,-0.01368415,0.032627197,-0.039293025,0.072355708,0.013170123,0.032471975,-0.110580392,-0.079481751,1.50774049,2.45803467,-4.187371046,-4.031954926,-4.874016167,-4.798267197,-4.337380013,-2.895236931,-5.299544085,-1.444952021 -2726,L167N,0.012186536,0.004682825,-0.027263979,-0.04314168,-2.83505775,0.206138436,-0.008085061,0.032458132,,-0.012988371,0.02235402,-0.04479086,-0.009737097,-0.055704893,-0.030578467,-2.216881907,-3.453233593,0.794928913,1.283006402,-14.36409107,-20.12345877,-13.15956712,-14.22891618,-13.76821361,-10.54029967,-9.458925519,-5.911648887 -2727,L167Q,-0.025009842,0.0135106,-0.020932681,-2.180382564,-2.735504062,0.065753485,0.002580647,-0.05260033,,-0.020663875,0.047685074,-0.059283906,0.017418545,-1.767046767,-2.593718361,-2.191827279,-3.279180844,0.725919014,0.683302739,-12.49625469,-19.05752506,-11.08569934,-11.49631896,-11.11901512,-9.722714981,-8.047710178,-3.448157 -2728,L167P,-0.039453729,0.035035965,-0.530823,-2.113015132,-2.538317974,0.076729069,-0.024626535,-0.054280922,,0.047148925,0.022923005,-0.391859358,-0.669786641,-1.978237449,-2.247792815,-2.444410645,-2.632225302,1.452976836,0.708712481,-11.83712751,-17.09582825,-11.10935645,-10.96690076,-10.89037295,-9.123179131,-7.699101584,-4.289282986 -2729,L167S,-0.014351083,0.005458002,-0.016160984,-1.139683851,-2.662568311,0.076663087,-0.013320123,-0.015382042,,-0.00714593,0.018061933,-0.030257128,-0.00206484,-1.401904049,-0.877463652,-2.424196924,-2.900939697,0.776848578,0.718859603,-9.927176151,-16.21591882,-8.575208069,-8.739439011,-9.445431244,-6.659883606,-6.647556096,-3.233205587 -2730,L167R,-0.034567012,-0.871267569,-2.004142992,-2.256873182,-2.840588155,0.082187305,-0.014647652,-0.054486372,,-0.837057613,-0.905477524,-2.157596429,-1.850689555,-2.136835003,-2.37691136,-2.64876569,-3.032410619,1.557747297,-0.237614016,-13.93177381,-20.18027886,-13.72998726,-13.11189227,-12.67489449,-9.961816154,-8.475420964,-2.8194087 -2731,L167T,0.020546643,0.025005515,-0.010561272,-0.007957307,-0.880212184,0.109915533,0.027238366,0.01385492,,0.006140019,0.043871011,-0.0332364,0.012113856,0.003372209,-0.019286823,-0.787387529,-0.973036838,0.653128762,1.372324932,-11.27823165,-15.72364294,-11.45486283,-9.830364952,-11.62343649,-7.758851013,-8.425423518,-2.863191862 -2732,L167W,-0.027229514,-1.191711332,-2.207127508,-2.420178964,-2.693164746,0.009473129,-0.006575446,-0.047883581,,-1.250436214,-1.13298645,-2.161196818,-2.253058197,-2.076317892,-2.764040035,-2.677189663,-2.709139828,2.72714215,0.276470417,-14.3268215,-17.92614049,-13.04169379,-14.29523395,-13.7422743,-12.62876496,-9.347819131,-5.555929061 -2733,L167V,-0.021767487,0.013677971,-0.026588597,0.015077031,-0.015985525,0.077525227,-0.043272734,-0.00026224,,0.000294519,0.027061423,-0.012361772,-0.040815422,0.025083797,0.005070264,0.002664655,-0.034635705,1.19486694,2.524753817,-6.699480588,-7.559443459,-7.721306976,-5.325364723,-7.947934357,-4.943353424,-5.608419897,-2.893151649 -2734,L167Y,-0.083214775,-1.315170882,-2.01003861,-2.575272585,-2.891833455,0.06711085,-0.055179812,-0.111249737,,-1.199548166,-1.430793598,-1.908204079,-2.111873141,-2.078597659,-3.07194751,-2.901318179,-2.88234873,3.593791867,1.297872375,-14.76272204,-15.8233928,-14.96389929,-14.2764202,-13.87926005,-14.87063786,-7.839318619,-3.700844714 -2735,N168A,0.027702993,-0.009094956,-0.03339603,0.005673558,-1.359565393,-0.048446896,0.028305074,0.027100912,,-0.004271942,-0.013917969,-0.073800815,0.007008756,-0.01509123,0.026438345,-1.196243907,-1.522886878,0.914516107,1.366908079,-9.126523216,-7.277275826,-14.09100336,-8.593677681,-8.244965416,-7.425693794,-5.821637629,-2.081454295 -2736,N168C,-0.01325563,-0.012540209,-0.048363623,-0.045854346,-1.797003822,-0.000978153,0.008471856,-0.034983115,,-0.017456994,-0.007623423,-0.057016313,-0.039710933,0.038708237,-0.130416928,-1.430731547,-2.163276097,0.555574898,1.317092617,-14.00026411,-11.64569988,-18.21824418,-13.32504812,-12.9114581,-13.90087027,-11.6279856,-9.458422852 -2737,N168E,-0.0000387,0.00361849,-0.031139855,-1.763905636,-2.469443095,-0.096990281,0.001509402,-0.001586755,,0.008690409,-0.00145343,-0.040304768,-0.021974941,-1.725728037,-1.802083234,-2.520799312,-2.418086878,0.663799748,0.684787363,-10.86717465,-8.780377304,-16.44189691,-10.96307677,-9.761955612,-8.388566635,-7.851916958,-1.686690935 -2738,N168D,-0.016348784,0.013938262,-0.004908568,0.013362128,-2.229169043,-0.069077432,-0.040028911,0.007331343,,0.003093694,0.024782829,-0.02548714,0.015670004,0.016728998,0.009995258,-1.948841053,-2.509497032,0.730867898,1.300021603,-7.233015863,-7.343699432,-9.151473084,-7.307486145,-7.624983475,-4.73743718,-6.998195143,-2.41321309 -2739,N168G,-0.012749712,0.004006979,-0.04231318,-0.012899643,-0.188527075,0.15916433,-0.017537862,-0.007961561,,0.022703462,-0.014689504,-0.048097811,-0.036528549,0.004758706,-0.030557992,-0.1951113,-0.18194285,1.497564007,2.203057435,-7.574360086,-4.861448395,-12.30845545,-7.189318138,-7.477850639,-6.034727806,-5.897142595,-3.210833887 -2740,N168F,-0.036188077,-0.02869126,-2.176010199,-2.138915059,-3.154169562,-0.018014429,-0.022340333,-0.05003582,,-0.008105856,-0.049276664,-2.199173629,-2.152846768,-1.966683135,-2.311146982,-2.886693146,-3.421645977,-0.131676896,-0.313319404,-12.48331656,-11.31033557,-18.82047555,-9.760250328,-9.90349913,-12.62202223,-8.151712283,-3.160304572 -2741,N168I,-0.030299376,0.011996325,-0.058600764,-0.660491721,-3.003262056,0.034643257,0.019767143,-0.080365894,,0.044122016,-0.020129367,-0.045647693,-0.071553835,-0.569083883,-0.751899559,-2.878259979,-3.128264132,0.737905638,0.828501829,-11.73072959,-9.761129509,-20.05451836,-11.14786073,-9.915852829,-7.774286537,-8.382528459,-4.441771364 -2742,N168H,0.00226338,0.034605168,-0.016642731,-1.940330186,-2.696715137,-0.000837478,0.018089136,-0.013562377,,0.039432868,0.029777467,-0.039498037,0.006212576,-1.790872518,-2.089787854,-2.318082161,-3.075348113,0.613076965,0.677220232,-10.61410474,-9.311944298,-14.52147174,-10.151797,-9.797473167,-9.287837486,-7.711861316,-1.935051848 -2743,N168K,-0.014803562,-0.081029332,-1.417230798,-1.921767634,-2.398846159,-0.034044146,0.001530306,-0.031137429,,-0.013153307,-0.148905356,-1.415079109,-1.419382487,-1.917274171,-1.926261096,-2.603200977,-2.194491341,2.774563298,1.23616369,-9.462417322,-8.870437248,-11.11032845,-9.763515137,-9.129233467,-8.438572304,-8.089901953,-2.142169553 -2744,N168M,-0.039988353,0.052027116,-0.040947177,-0.750830269,-3.19008805,-0.047542328,-0.016914491,-0.063062215,,0.097761312,0.006292919,-0.016877244,-0.06501711,-0.72662886,-0.775031678,-2.893793487,-3.486382612,0.543112768,0.759878215,-11.60186373,-10.09000655,-15.90326514,-11.78889699,-9.566489647,-10.66066033,-7.989281047,-4.557547276 -2745,N168L,-0.012061582,0.040232698,-0.0157709,-1.926498173,-3.202224799,0.022518742,0.000942265,-0.025065429,,0.048384747,0.032080649,-0.016637391,-0.014904408,-1.780330097,-2.072666249,-2.728368832,-3.676080766,0.426496676,0.672897152,-10.71272261,-9.220646629,-14.66185291,-11.71016505,-9.79449485,-8.176453606,-7.925686445,-3.257321755 -2746,N168Q,0.009936038,-0.009388161,-0.033667106,-0.007293884,-1.962057184,-0.072495285,0.000963779,0.018908297,,0.00751424,-0.026290562,-0.043939623,-0.023394588,-0.003731669,-0.010856099,-1.807792543,-2.116321824,0.705691073,1.306688555,-10.56402587,-8.25310379,-12.71518896,-11.40839144,-9.895582031,-10.54786311,-6.281429658,-1.861619819 -2747,N168P,-0.022543258,-0.053302765,-1.893528171,-2.119602669,-2.963152876,0.096662916,0.002772258,-0.047858774,,0.039615855,-0.146221384,-1.967007568,-1.820048773,-1.997758508,-2.24144683,-2.674730471,-3.25157528,0.18946537,-0.124011528,-13.40059995,-11.10473385,-20.53084682,-12.63365673,-12.43498397,-10.2987784,-7.467804887,-2.978160861 -2748,N168S,-0.022687142,0.013039978,-0.056499956,-0.024092476,-0.958670944,-0.098234324,-0.019178851,-0.026195432,,0.02993794,-0.003857984,-0.063967312,-0.0490326,0.011596142,-0.059781094,-0.750897956,-1.166443931,0.777474062,1.399002391,-6.071191643,-4.453283234,-8.356821259,-6.044899185,-6.951778618,-4.549175919,-4.973691514,-2.300417911 -2749,N168R,0.007559675,0.012341681,-0.037646281,-1.490333692,-2.367051715,-0.06163486,0.027784948,-0.012665599,,0.014489464,0.010193897,-0.03317113,-0.042121432,-1.290999049,-1.689668334,-2.1732205,-2.56088293,2.251028355,1.445555651,-13.25856069,-10.63524261,-20.23337785,-11.79845706,-11.98309607,-11.64262983,-7.783224854,-3.235316816 -2750,N168T,0.021947928,0.022445983,-0.002035756,0.016570587,-1.293284521,-0.004696055,0.036356236,0.007539619,,0.023988056,0.02090391,-0.02548714,0.021415629,0.025294316,0.007846857,-1.212082488,-1.374486554,0.636832294,1.332523842,-6.951776915,-4.422975647,-10.87258549,-6.926874718,-6.748291328,-5.788157394,-5.559235751,-2.635500592 -2751,N168W,-0.031114618,-0.007513701,-1.021455737,-2.101124509,-2.558682303,-0.007068141,-0.010373081,-0.051856154,,0.031132326,-0.046159728,-0.92742454,-1.115486933,-1.625462281,-2.576786736,-2.129048878,-2.988315727,3.556933064,2.290038213,-14.18874816,-12.68971303,-21.38017712,-11.98573254,-12.41764028,-12.47047782,-9.272486792,-5.834570982 -2752,N168V,-0.036888833,0.013501684,-0.020325594,-0.013474015,-2.083815125,0.011870186,-0.023684443,-0.050093223,,0.010534467,0.016468901,-0.009389774,-0.031261414,0.021047171,-0.047995201,-1.800954738,-2.366675511,0.622444378,1.304458249,-11.02579138,-8.915292519,-19.31251488,-9.910659874,-9.139690224,-7.850799393,-7.495717177,-3.061445821 -2753,N168Y,-0.012523528,-0.213043403,-1.70179649,-1.97689715,-2.451047804,-0.052862982,-0.007959648,-0.017087408,,-0.136210182,-0.289876623,-1.515299571,-1.888293409,-1.746566369,-2.207227931,-2.026727829,-2.875367778,4.137193597,2.577473277,-13.26626471,-12.16046127,-20.79598386,-10.28164162,-9.793434784,-13.29980202,-7.945561959,-2.920175397 -2754,E169A,-0.013146613,-0.027920058,0.013182038,0.032935587,0.011510119,0.006481969,-0.011517522,-0.014775704,-0.004955326,-0.03267412,-0.023165996,0.011726273,0.014637802,0.025267848,0.040603326,-0.006917857,0.029938094,1.113877919,2.622313949,-5.425133618,-5.084872612,-5.823355362,-6.278298256,-5.023430412,-4.915711449,-4.614855783,-0.869946311 -2755,E169C,-0.044431463,-0.076521512,-0.030147798,0.016529485,-0.23286086,0.153985829,-0.077825339,-0.011037587,0.079273029,-0.040166881,-0.112876143,-0.037949402,-0.022346193,0.042533344,-0.009474375,-0.224149142,-0.241572577,1.272019361,1.984317623,-10.78731823,-10.87660532,-11.29960007,-10.76334898,-10.72244277,-10.274594,-8.906941512,-6.470511875 -2756,E169D,-0.117932285,-0.055504745,-0.078598005,-0.012707439,-0.048479077,0.068240287,-0.06462208,-0.171242489,-0.071032834,-0.07859567,-0.032413819,-0.073548938,-0.083647072,-0.020452783,-0.004962095,-0.074395664,-0.02256249,1.35092152,2.335706408,-4.895813481,-5.904384468,-4.861368973,-3.46307386,-5.779126335,-4.47111377,-4.446669371,-1.15204545 -2757,E169G,0.004134853,-0.029662321,-0.003889637,0.003928237,-0.020031158,0.050376516,-0.014144148,0.022413854,0.011000949,-0.037607575,-0.021717067,-0.027503386,0.019724112,-0.005201187,0.01305766,-0.07398067,0.033918355,1.42174823,2.52135041,-8.441202373,-7.957720696,-7.412193405,-9.925747925,-8.321731483,-8.588618355,-6.289660338,-2.409301656 -2758,E169F,-0.054640235,-0.027866085,-0.032521503,0.000643821,-0.224830355,0.477489924,-0.063176471,-0.046103999,0.048538412,-0.049743731,-0.005988438,-0.034460207,-0.030582799,0.033747459,-0.032459818,-0.181725308,-0.267935402,1.554838161,2.2813231,-9.237172414,-10.43910875,-11.45598996,-6.87928054,-8.529064598,-8.882418221,-6.242579783,-3.987417858 -2759,E169I,-0.040801242,-0.06526406,-0.078477533,-0.050810062,-0.251659858,0.372186551,-0.069846871,-0.011755613,-0.023693974,-0.044489962,-0.086038158,-0.016938198,-0.140016868,-0.014070771,-0.087549352,-0.202314875,-0.301004841,1.354273407,2.091480687,-9.423099571,-9.998399757,-11.65209348,-7.563063057,-8.640906548,-9.261035019,-5.107877586,-3.279966917 -2760,E169H,-0.013537697,-0.030557823,0.000745939,0.011691958,-0.09894873,0.186106804,-0.035454348,0.008378954,-0.025054632,-0.033811473,-0.027304173,-0.012991273,0.01448315,0.022186229,0.001197687,-0.150576133,-0.047321326,1.435844083,2.295209992,-6.938597821,-8.722697441,-8.019606049,-6.31415818,-7.913842155,-3.72268528,-5.664461507,-2.955879189 -2761,E169K,-0.040393071,-0.051042555,-0.020801314,-0.001990581,-0.030407853,0.04244703,-0.058810975,-0.021975167,-0.066001089,-0.029846359,-0.072238751,-0.052981438,0.01137881,-0.012263484,0.008282322,-0.053348422,-0.007467284,1.200955754,2.274459833,-7.005384839,-8.797671783,-6.331008995,-7.896524086,-6.960222664,-5.041496666,-5.899231788,-1.621503296 -2762,E169M,0.033258774,-0.003463641,0.029718662,0.011395822,0.021681986,0.028200058,-0.008269683,0.074787231,0.006340732,-0.01084615,0.003918869,-0.003076559,0.062513883,0.003676408,0.019115235,-0.021945594,0.065309565,1.322020553,2.539203136,-9.331992993,-9.668196526,-9.985913589,-8.902897858,-8.952965462,-9.149991531,-6.418977655,-4.052849052 -2763,E169L,-0.007609197,-0.05711495,-0.021691306,-0.003484479,-0.084152105,0.09332073,-0.043331031,0.028112637,0.035366966,-0.058407116,-0.055822783,-0.025963486,-0.017419125,-0.013539006,0.006570049,-0.099569128,-0.068735081,1.453277929,2.385105567,-8.538693277,-8.754970505,-10.67597267,-7.262975929,-7.941477219,-8.058070061,-5.362389916,-2.523386368 -2764,E169N,-0.045041811,-0.025481512,-0.039400113,0.002681044,-0.075607926,0.295262565,-0.032926343,-0.057157278,-0.041923844,-0.033148146,-0.017814878,-0.040954321,-0.037845904,-0.022223878,0.027585966,-0.117819047,-0.033396804,1.379760888,2.238939265,-6.058441847,-7.323574768,-6.875054176,-4.530294289,-7.094647949,-4.468638054,-5.4323726,-2.576979176 -2765,E169Q,-0.083875059,-0.089191428,-0.033969347,-0.023917543,-0.038255578,0.00332058,-0.074309583,-0.093440535,-0.028028169,-0.090824636,-0.087558219,-0.013583635,-0.054355058,-0.008911804,-0.038923282,-0.062441757,-0.014069398,1.254038725,2.341571275,-2.887443069,-3.446541031,-2.830350899,-3.618532776,-2.676539993,-1.865250649,-3.212586872,-1.686121252 -2766,E169P,-0.096936527,-0.055726847,-0.020217608,-0.141018043,-2.145505745,0.043369786,-0.074502547,-0.119370506,-0.00089823,-0.03770605,-0.073747643,-0.023924852,-0.016510364,-0.079020974,-0.203015112,-2.046973891,-2.244037598,1.069894943,1.307908514,-9.126873438,-9.656727425,-7.430089386,-9.695175575,-9.536694115,-9.315680687,-6.042519556,-2.00927826 -2767,E169S,-0.058392851,-0.064887789,-0.037797186,-0.022503406,-0.016386099,0.004409585,-0.069649085,-0.047136617,0.010238465,-0.06127796,-0.068497617,-0.043934372,-0.03166,-0.03262013,-0.012386681,-0.05087649,0.018104292,1.124615063,2.223742174,-3.066955905,-2.662507721,-3.064725456,-4.425564362,-2.497074814,-2.684907173,-2.777340221,-0.489856116 -2768,E169R,-0.034445094,-0.045611207,-0.024138101,-0.003729187,-0.041936411,0.14916386,-0.053449123,-0.015441064,0.006449184,-0.045367888,-0.045854526,-0.03923406,-0.009042142,-0.014258362,0.006799988,-0.091242153,0.007369331,1.432380339,2.365524762,-5.939572345,-8.750249702,-5.629049858,-6.963762108,-6.282610687,-2.072189369,-5.686207806,-0.971105889 -2769,E169T,-0.043440236,-0.05028254,-0.01517074,-0.0047726,-0.028245622,-0.050022255,-0.060416651,-0.02646382,0.018315986,-0.035126712,-0.065438367,-0.018021348,-0.012320132,-0.013929063,0.004383863,-0.037645767,-0.018845477,1.250002193,2.408237251,-4.460786493,-3.216110893,-4.226266548,-5.283952217,-4.965078125,-4.612524681,-3.131633117,-0.727929292 -2770,E169W,-0.028613757,-0.003827443,-0.007942851,-0.015955637,-0.125559554,0.32242019,-0.045701035,-0.011526479,-0.037558497,0.005600701,-0.013255586,-0.027895425,0.012009724,-0.032901463,0.00099019,-0.135557311,-0.115561797,1.428445303,2.263872953,-12.04358384,-12.94824781,-13.43204654,-11.51642675,-11.74650212,-10.57469596,-9.936621473,-8.871417516 -2771,E169V,0.004141992,-0.044761579,-0.040031474,-0.012339617,-0.136233655,0.260524902,-0.014407304,0.022691288,0.009910995,-0.073964433,-0.015558725,-0.077513412,-0.002549535,-0.041939255,0.017260021,-0.171707758,-0.100759551,1.35170944,2.14145819,-7.989681133,-8.106109734,-10.11983805,-6.062942406,-7.201417801,-8.458097672,-5.623025441,-2.403127181 -2772,E169Y,-0.018404298,-0.029936548,-0.038754091,-0.024273212,-0.222237047,0.495267162,-0.01218008,-0.024628516,-0.007669982,-0.04206606,-0.017807036,-0.06210908,-0.015399102,-0.044360729,-0.004185695,-0.252680138,-0.191793955,1.339130369,1.950488533,-8.096605988,-9.803874062,-10.63851283,-5.563165352,-7.780311317,-6.697166374,-5.668583919,-3.481176093 -2773,A170C,-0.052773188,-0.096157354,0.081670243,-0.086413306,-0.095774798,0.067317312,-0.076303974,-0.029242402,0.053093261,-0.143113455,-0.049201253,0.011367609,0.151972877,-0.084114253,-0.088712358,0.018314207,-0.209863803,1.25999479,2.58105472,-10.44077623,-11.38113672,-10.68103928,-10.05096712,-9.979572014,-10.11116599,-8.592889901,-5.866684601 -2774,A170E,-0.121502463,-0.063075419,0.022378403,-0.047354243,-1.638338553,0.076781946,-0.062873689,-0.180131237,0.010155439,-0.183231358,0.057080521,0.001886748,0.042870058,-0.036413418,-0.058295067,-1.451702721,-1.824974384,0.748324407,1.324960167,-10.31142313,-11.80940947,-9.454102921,-12.95318264,-8.389646324,-8.950774277,-7.93025815,-3.689510933 -2775,A170D,-0.12075219,-0.116378365,-0.023475748,-0.018752912,-1.236433786,-0.019428552,-0.091515924,-0.149988456,-0.032476619,-0.155673354,-0.077083376,-0.10042847,0.053476975,-0.027146734,-0.010359089,-1.021038868,-1.451828703,0.631843199,1.344920623,-9.92497505,-11.12809231,-8.076365311,-13.81858656,-8.002775932,-8.599055138,-7.213962577,-1.981770607 -2776,A170G,-0.032415071,-0.041782677,0.025310166,-0.02862125,-0.062819829,0.006997078,-0.028266423,-0.036563719,0.005474749,-0.110314043,0.026748689,-0.024201425,0.074821757,-0.035454861,-0.021787638,-0.032359823,-0.093279834,1.408082595,2.556899191,-3.998827403,-5.538603203,-3.517192902,-4.806930519,-2.907747635,-3.223662758,-5.236393617,-2.506058528 -2777,A170F,-0.046228883,-0.038893992,0.019507549,-0.055667898,-0.379657619,0.55958691,-0.018884077,-0.073573689,0.066094737,-0.125837052,0.048049069,-0.067852941,0.106868039,-0.102150365,-0.00918543,-0.283700702,-0.475614536,1.648111847,2.157419978,-12.13811876,-9.776086876,-14.40156111,-12.56584692,-11.49757026,-12.44952863,-6.655469915,-2.974485878 -2778,A170I,-0.104907158,-0.052635375,0.066169441,-0.031905413,-0.499302942,0.042054384,-0.066759379,-0.143054936,0.003799796,-0.117964626,0.012693877,-0.011143063,0.143481945,-0.021173452,-0.042637374,-0.447772428,-0.550833455,1.260561951,1.709475478,-12.64740321,-12.57925598,-15.80080974,-11.66315922,-11.07511851,-12.11867262,-7.112119137,-3.263873031 -2779,A170H,-0.065961038,-0.054769974,0.015158224,-0.019989411,-0.422100168,0.711755388,-0.066052494,-0.065869581,-0.011520839,-0.078210163,-0.031329785,0.048119397,-0.01780295,-0.000631242,-0.039347579,-0.175818989,-0.668381347,1.151753969,1.965499363,-11.79096771,-13.9413994,-12.67059221,-12.27446781,-10.16410275,-9.904276375,-8.67328071,-5.14187175 -2780,A170K,-0.186013484,-0.022392553,0.057503161,-0.066294609,-2.138205066,0.123040496,-0.075433113,-0.296593854,0.022355091,-0.142639708,0.097854603,0.070054324,0.044951998,0.030163916,-0.162753134,-1.697215389,-2.579194743,0.595203321,1.306977082,-10.48569397,-13.70631238,-9.503845558,-11.31636265,-9.653880615,-8.248068626,-7.373055672,-3.62545214 -2781,A170M,-0.020488045,0.022837259,0.071874713,-0.022317044,-0.651438708,0.222044188,0.03859571,-0.079571799,0.011356542,-0.018424567,0.064099085,0.038650977,0.105098448,-0.012859223,-0.031774865,-0.603793704,-0.699083712,0.597992691,1.393153012,-13.57327263,-14.12124318,-14.90980766,-13.70247703,-12.633886,-12.49894929,-8.75654738,-5.161878933 -2782,A170L,0.006327951,-0.041927394,0.033883849,-0.036705456,-1.003401435,0.10953636,-0.002155978,0.014811879,0.004971412,-0.168503318,0.084648531,-0.068989503,0.1367572,-0.073875734,0.000464823,-0.777766449,-1.229036421,1.264081611,1.553909691,-13.60284708,-13.60104256,-14.91455549,-13.6224366,-13.19736761,-12.67883314,-8.182010365,-4.0588607 -2783,A170N,-0.131387142,-0.027158273,0.028140192,-0.05820261,-0.31425025,0.010971807,-0.031449642,-0.231324642,0.029082811,-0.078150585,0.02383404,0.003752286,0.052528098,-0.057276793,-0.059128426,-0.265301317,-0.363199182,1.634631889,2.184577605,-7.969261559,-10.72011871,-8.069554794,-9.798834579,-5.469021004,-5.788778709,-5.317546362,-2.12183132 -2784,A170Q,0.027145552,0.069486243,0.084380882,0.001669681,-1.585160314,0.190289371,0.087083616,-0.032792513,-0.008153514,0.022914105,0.116058381,0.050594502,0.118167261,0.030206892,-0.026867531,-0.981989655,-2.188330972,0.670563404,1.353105544,-11.38778377,-13.23523441,-11.02280081,-13.37741454,-9.830391083,-9.473078026,-7.833888245,-2.808958799 -2785,A170P,0.043094791,0.019750567,0.090874703,0.028561856,-0.502327118,0.693849974,0.024715523,0.061474059,-0.007610122,-0.058313847,0.09781498,0.034648311,0.147101095,0.026825947,0.030297765,-0.39810587,-0.606548365,0.953934636,1.589823449,-9.760103879,-10.21045109,-10.52354304,-9.219587654,-9.673593323,-9.173344292,-7.53036986,-4.078761878 -2786,A170S,-0.012677213,-0.065358794,0.075523593,-0.016748596,-0.010849722,0.041644968,-0.056331584,0.030977158,0.036948743,-0.17409524,0.043377652,-0.037498266,0.188545452,-0.047278939,0.013781748,0.004223781,-0.025923224,1.671448915,3.643209181,-4.338230475,-5.460875328,-4.222390488,-4.525577087,-3.648299286,-3.834010185,-5.757351579,-2.488701164 -2787,A170R,-0.058899272,-0.051966163,0.035635582,-0.008292167,-0.900379702,0.265587234,-0.063934458,-0.053864086,-0.025471855,-0.097870189,-0.006062137,0.016960384,0.05431078,-0.022699078,0.006114745,-0.5862753,-1.214484103,1.037642219,1.525760407,-9.796182004,-11.34121505,-11.08965739,-10.506607,-7.77803212,-8.265398453,-6.900113656,-2.661912079 -2788,A170T,0.01888895,-0.067069146,-0.012372215,-0.014465439,-0.720405674,0.301163232,0.010256826,0.027521074,-0.013352519,-0.16176717,0.027628879,-0.129471485,0.104727055,-0.059001412,0.030070535,-0.542671067,-0.89814028,1.342121253,1.701944443,-7.358760269,-8.112083878,-9.172879478,-7.571365158,-5.765362366,-6.172110466,-6.718838396,-3.085740469 -2789,A170W,0.020925604,-0.030874173,0.027723814,0.003772246,-0.213755331,0.409663308,0.014750846,0.027100362,0.005510534,-0.093587555,0.03183921,-0.058755339,0.114202967,-0.069717418,0.07726191,-0.17950503,-0.248005631,1.591522749,2.299623932,-12.5496565,-14.7277241,-12.0736616,-12.33420898,-12.24720695,-11.36548086,-7.144091575,-3.122589728 -2790,A170V,-0.053605871,-0.03109561,0.045429724,-0.007219354,-0.22716539,0.212341394,-0.055002763,-0.052208979,0.018472688,-0.122461897,0.060270678,0.028668055,0.062191392,0.016174568,-0.030613275,-0.124140113,-0.330190666,1.470164964,2.335729421,-8.372579536,-9.69791011,-12.21688485,-6.91859272,-6.284383392,-6.74512661,-5.809460225,-1.974498799 -2791,A170Y,-0.09593548,-0.091819408,0.038564451,-0.11199079,-0.152466172,0.529521037,-0.101818502,-0.090052458,-0.037726292,-0.153821349,-0.029817466,-0.01460743,0.091736332,-0.11960313,-0.104378449,-0.105183534,-0.19974881,1.426176557,2.282320266,-12.45360946,-11.17721536,-13.40752909,-12.90599371,-11.55923056,-13.21807857,-7.293194407,-3.900950079 -2792,I171A,-0.09631298,0.123721611,0.018986278,-0.067352633,0.019637073,0.100967011,-0.064098513,-0.128527446,-0.078600752,0.22959356,0.017849662,0.223860152,-0.185887597,0.086274873,-0.220980138,0.216932608,-0.177658463,0.937099349,3.171290316,-1.667224072,-1.573439697,-2.4989618,-2.111166183,-1.261580521,-0.89097216,-2.885502581,-0.364511606 -2793,I171C,-0.202202089,0.100635202,-0.018744358,-0.05918535,-0.033828286,0.024588828,-0.138642336,-0.265761841,-0.018179748,0.176359923,0.024910481,0.188550065,-0.22603878,0.160654745,-0.279025445,0.179040326,-0.246696898,1.087665001,3.101080646,-6.634358015,-6.658246017,-7.275842529,-6.75342086,-6.480945,-6.00333567,-6.73479882,-4.16694674 -2794,I171E,-0.039921768,0.154594606,0.04851653,-0.021653235,0.01487968,0.081751542,-0.010234085,-0.069609451,-0.081372888,0.279657579,0.029531633,0.26833736,-0.1713043,0.151801434,-0.195107903,0.262677103,-0.232917744,0.980954493,3.095172161,-3.078656253,-2.830795822,-3.654275429,-3.760824417,-2.901530167,-2.245855431,-3.416629285,-0.814657466 -2795,I171D,-0.105579122,0.049574337,0.01540961,-0.033377748,-0.095848309,0.099263247,-0.024821131,-0.186337113,-0.083274533,0.225882356,-0.126733682,0.244703077,-0.213883857,0.143456055,-0.21021155,0.107243882,-0.2989405,1.039961386,2.981270359,-5.125279832,-4.120596802,-7.698628677,-5.284847183,-4.243056229,-4.279270271,-4.793871306,-1.889711446 -2796,I171G,-0.061039008,0.133327904,0.036276848,-0.028479956,-0.010270764,0.158870544,-0.019094265,-0.10298375,-0.056878736,0.237138602,0.029517206,0.249424749,-0.176871053,0.114932501,-0.171892412,0.219258895,-0.239800423,0.945775863,3.07879746,-4.16947151,-4.370144341,-5.124734833,-4.661456009,-3.891563728,-2.799458641,-4.256685672,-1.919976082 -2797,I171F,-0.126633636,0.213098512,-0.02566361,-0.029540465,0.072452323,0.193212196,-0.035480728,-0.217786543,-0.044191052,0.397135014,0.02906201,0.331382983,-0.382710202,0.222315482,-0.281396411,0.2726206,-0.127715955,1.671448915,3.643209181,-3.434239246,-3.907214386,-2.965072594,-1.898353752,-4.141246384,-4.259309113,-4.545035477,-0.757552022 -2798,I171H,-0.095188078,0.124239645,0.06992852,-0.062571532,-0.076070341,0.219538667,-0.048235826,-0.142140329,-0.055769241,0.200840369,0.04763892,0.287477497,-0.147620458,0.107418684,-0.232561748,0.239128981,-0.391269663,1.081456891,3.326634286,-4.323939069,-4.828925568,-4.291607933,-3.829623985,-4.364765259,-4.304772598,-4.635746769,-1.914659769 -2799,I171K,-0.203857835,0.010062871,-0.013814214,-0.111687403,-0.029810137,0.09286495,-0.161154136,-0.246561534,-0.169200286,0.209314676,-0.189188934,0.166661339,-0.194289766,0.051706823,-0.275081628,0.201323187,-0.26094346,1.020937332,3.080219537,-0.974225342,-1.14402272,-2.254477058,-0.829373238,-0.769420418,0.126166725,-2.767249597,-1.027763009 -2800,I171M,-0.13282428,0.107193561,-0.032061623,-0.169560513,-0.084325252,0.109129502,-0.053226992,-0.212421568,-0.063419473,0.23862893,-0.024241809,0.258832316,-0.322955562,0.045183996,-0.384305022,0.226451651,-0.395102154,1.148701582,3.230137117,-2.64753745,-2.986726212,-3.507819717,-2.473800102,-2.537389671,-1.731951546,-5.024949405,-2.607687399 -2801,I171L,-0.053029779,0.168472901,0.059931007,-0.027830146,0.009850653,0.029297893,-0.012498257,-0.093561301,-0.055530389,0.282488665,0.054457137,0.288892415,-0.169030401,0.134323106,-0.189983398,0.281113008,-0.261411702,0.859731284,3.121536077,1.0263578,0.287215218,1.278799248,2.031100266,0.647093887,0.887580383,0.088597197,0.199035965 -2802,I171N,-0.117746345,0.104182319,0.035746762,-0.047183872,-0.006277549,0.135208309,-0.065961348,-0.169531342,-0.152261864,0.217230785,-0.008866148,0.214085989,-0.142592466,0.132814586,-0.22718233,0.225817876,-0.238372973,0.938734757,3.108829711,-4.245105354,-3.861139404,-4.668823608,-4.565625839,-4.267959625,-3.861978294,-4.362628681,-2.489208616 -2803,I171Q,-0.136780133,0.15140254,0.051563801,-0.045629091,-0.016285197,0.079487315,-0.100173568,-0.173386698,-0.021028894,0.319744676,-0.016939597,0.312133043,-0.209005441,0.170278926,-0.261537108,0.261245422,-0.293815815,1.543610422,3.106887046,-3.177733354,-2.949547638,-4.291876266,-3.722390068,-2.456833984,-2.468018814,-3.879974675,-1.38447674 -2804,I171P,-0.050206258,0.1580078,0.086546979,-0.032749404,-0.622117062,0.385792779,0.005079394,-0.10549191,-0.055715551,0.256918148,0.059097451,0.267297332,-0.094203374,0.092493311,-0.157992119,-0.256510288,-0.987723836,0.879569463,1.708410158,-4.046796228,-4.375724823,-6.01796096,-4.015357124,-3.662144844,-2.162793388,-4.828722397,-0.660251418 -2805,I171S,-0.066464517,0.095458756,0.020383314,-0.030746639,0.007955541,0.161989052,-0.016627085,-0.116301948,-0.056002404,0.222523897,-0.031606385,0.245235301,-0.204468674,0.068267565,-0.129760843,0.1495418,-0.133630718,1.046618325,3.208839672,-3.094085936,-3.052564186,-3.742313171,-3.4594869,-3.055878647,-2.160186775,-3.058052722,-1.143411892 -2806,I171R,-0.088703603,0.118916887,0.041168409,-0.026153707,0.007069098,0.071385272,-0.061478599,-0.115928606,-0.033245416,0.235205655,0.002628118,0.254470718,-0.1721339,0.138340256,-0.19064767,0.244125896,-0.229987701,0.953412496,3.162273815,-1.467863918,-1.367263748,-2.396842224,-2.139248489,-1.013394325,-0.422570801,-2.735783614,-0.522473437 -2807,I171T,-0.02400513,0.180240328,0.082866377,-0.020739307,-0.012082141,0.171668552,0.041556092,-0.089566352,-0.023871762,0.295898377,0.064582278,0.305764256,-0.140031502,0.12879652,-0.170275134,0.268413272,-0.292577553,0.926636351,3.060451591,-0.573238718,0.500868126,-1.867733803,-1.834704613,0.077572639,0.257804062,-2.07455144,-0.457029968 -2808,I171W,-0.025844596,0.140569231,0.054273255,-0.007553622,0.011755136,0.097088625,0.026553676,-0.078242867,-0.024969222,0.236474279,0.044664183,0.256343515,-0.147797006,0.121139603,-0.136246847,0.212273544,-0.188763272,1.671448915,3.643209181,-6.475497278,-6.831224152,-7.058029472,-5.848274979,-6.127106827,-6.51285096,-5.753042872,-0.620947563 -2809,I171V,-0.119862614,0.110456657,0.022800403,-0.042349437,-0.011763924,0.082768768,-0.056777793,-0.182947435,-0.075044644,0.211230685,0.009682628,0.267117468,-0.221516663,0.120388609,-0.205087482,0.212123989,-0.235651836,0.997357017,3.08446084,-1.184860056,-1.065161041,-1.460971931,-1.950264725,-0.898380905,-0.549521675,-2.700971288,-0.430870839 -2810,I171Y,-0.13774284,0.112341239,0.019757903,0.006720588,0.049878287,0.139107693,-0.088532538,-0.186953142,-0.016730054,0.255627176,-0.030944698,0.263452514,-0.223936708,0.217583822,-0.204142647,0.357551549,-0.257794975,1.014288975,3.333851893,-5.022214557,-5.769217133,-3.248272949,-4.71504686,-5.598350494,-5.780185349,-5.131600893,-0.170870913 -2811,P172A,0.001117875,0.002953297,-0.006095497,0.022475883,-0.054554334,0.040140858,-0.005488701,0.00772445,0.019277943,0.015655931,-0.009749337,0.005751358,-0.017942351,0.044389895,0.000561871,-0.044741645,-0.064367023,1.231996208,2.442412546,-4.184918288,-4.363418381,-4.842446083,-4.257608513,-3.499072044,-3.962046417,-6.062814759,-1.737704073 -2812,P172C,-0.076966133,-0.040921808,-0.010724445,-0.035253481,-0.232375688,0.033277223,-0.076007113,-0.077925153,0.084261453,0.002409814,-0.084253429,0.038859607,-0.060308497,-0.008915731,-0.06159123,-0.122154394,-0.342596981,1.330674272,2.241012084,-10.34097992,-10.69435436,-11.7499348,-10.67926831,-9.390919685,-9.190422462,-11.0198473,-8.034165643 -2813,P172E,0.001968066,0.001442035,-0.022126802,0.02185824,0.013131383,0.047142548,-0.009442132,0.013378264,0.011018408,0.030556952,-0.027672883,-0.025078303,-0.0191753,0.038753824,0.004962655,-0.014126159,0.040388924,1.546473607,2.938183126,-5.779987204,-6.171462502,-6.462473152,-6.00425502,-5.002051796,-5.25969355,-6.166718781,-1.466313471 -2814,P172D,0.001952707,-0.082176293,-0.06239503,-0.068523337,-0.162923428,0.103830401,0.007719485,-0.003814071,0.006812686,-0.065372523,-0.098980062,-0.056506146,-0.068283913,-0.072608718,-0.064437956,-0.08508599,-0.240760865,1.3550698,2.300046148,-6.691720938,-5.931287666,-8.411797234,-6.470429413,-6.495994247,-6.14909613,-5.814514603,-1.030554757 -2815,P172G,0.011769867,-0.020191912,-0.01692597,-0.023617415,-0.2926104,0.19001301,0.01312699,0.010412743,0.024247391,-0.019344609,-0.021039214,-0.028432613,-0.005419326,-0.019351301,-0.027883529,-0.230312333,-0.354908466,1.658533535,2.263259212,-7.077279788,-7.402169594,-8.359193871,-7.290476418,-6.119342834,-6.215216225,-7.521392221,-3.313578728 -2816,P172F,-0.019773916,-0.004722398,-0.021259545,-0.018058491,-0.209981855,0.035778913,-0.036455581,-0.00309225,-0.017661083,-0.015004597,0.005559801,-0.002258296,-0.040260793,-0.010472129,-0.025644852,-0.169047753,-0.250915957,1.544516459,2.29839057,-10.26263951,-10.68089321,-12.48024335,-10.90829728,-8.520697418,-8.723066292,-9.198343392,-6.156125901 -2817,P172I,-0.107478003,-0.109593588,-0.155593595,-0.102566746,-0.179605393,0.018884004,-0.104544741,-0.110411265,0.007633354,-0.075410433,-0.143776742,-0.092297469,-0.218889721,-0.089108322,-0.116025169,-0.182890534,-0.176320252,1.566543783,2.239060652,-6.840779039,-7.644942154,-7.671185356,-7.601037819,-5.123333809,-6.163396057,-7.012814838,-3.997347323 -2818,P172H,0.078248106,0.005676646,-0.003009014,0.060013898,-0.099280105,0.037115569,0.08689524,0.069600972,0.045825175,-0.039116498,0.05046979,-0.029967285,0.023949257,0.000982995,0.119044801,-0.146234959,-0.05232525,1.233807273,2.081520001,-7.895547705,-8.447533768,-10.3138877,-7.395786018,-7.007332916,-6.313198128,-7.452325408,-3.656322212 -2819,P172K,-0.069295913,-0.02546872,-0.012185338,-0.02600526,-0.150293483,0.061738816,-0.061533097,-0.077058728,0.037856245,0.039312171,-0.09024961,0.017291669,-0.041662345,0.002003096,-0.054013616,-0.063209806,-0.237377159,1.306502148,2.41036893,-4.889110747,-6.084968941,-4.254709175,-6.044946983,-4.329465317,-3.731463318,-6.606969952,-1.797037565 -2820,P172M,0.016380444,0.006183593,0.027069726,0.005683074,-0.063852169,0.041613359,0.019783055,0.012977833,0.084725267,0.021510195,-0.009143009,0.012887692,0.04125176,0.01167293,-0.000306782,-0.113176411,-0.014527926,1.325568531,2.276970377,-7.30287317,-8.204166183,-8.82109285,-8.740728683,-5.507420311,-5.240957825,-7.46083837,-4.123267578 -2821,P172L,-0.013239043,-0.012600623,-0.008347556,0.013031208,-0.088987201,0.045285132,-0.016003924,-0.010474162,-0.008864002,0.015493691,-0.040694936,0.009441395,-0.026136506,0.043929321,-0.017866905,-0.06366941,-0.114304992,1.324738104,2.446562814,-5.328741734,-5.797363373,-6.869375175,-6.456270546,-3.921031837,-3.59966774,-5.530288904,-2.202995031 -2822,P172N,-0.022093703,0.031018935,-0.006068476,-0.023893327,-0.170574423,0.136605588,-0.005995673,-0.038191733,0.026153252,0.013900105,0.048137764,0.041208662,-0.053345613,-0.037186115,-0.010600538,-0.192735469,-0.148413376,1.276463678,1.982014116,-7.211386871,-7.369155075,-8.078953957,-8.234123947,-6.789147095,-5.585554283,-7.998315491,-2.695125687 -2823,P172Q,0.018725474,0.003644287,-0.039118791,-0.045657909,-0.064381216,0.007023507,-0.036191491,0.073642439,0.03482979,-0.008019714,0.015308287,-0.057433949,-0.020803633,-0.078756951,-0.012558866,-0.079353946,-0.049408486,1.380362695,2.33842162,-5.748854114,-6.811698448,-6.159942566,-5.824483391,-4.792270454,-5.15587571,-6.688081261,-2.453653873 -2824,P172S,-0.011998831,-0.020994856,-0.031657725,-0.029486734,-0.142501876,0.04294368,-0.037138929,0.013141268,-0.001029218,-0.043079157,0.001089446,-0.046502501,-0.016812949,-0.018540195,-0.040433273,-0.137355525,-0.147648226,1.318005127,2.142580397,-5.426282378,-5.737481026,-5.927299522,-6.005817719,-4.714068672,-4.746744949,-6.542918154,-2.677748152 -2825,P172R,-0.032054837,-0.032427656,-0.032357698,-0.028632402,-0.194723749,0.097271059,-0.026794883,-0.037314791,-0.009618363,-0.021264424,-0.043590887,-0.049636055,-0.01507934,-0.03352142,-0.023743383,-0.153306189,-0.236141308,1.538396819,2.305254609,-5.98171881,-6.366349266,-8.162817741,-5.58078141,-5.054556938,-4.744088692,-6.929385623,-2.19294624 -2826,P172T,-0.034828631,0.018208694,-0.019928028,-0.018340461,-0.091111296,0.07525266,-0.029939896,-0.039717366,0.035008402,0.006623466,0.029793922,-0.019088669,-0.020767386,-0.004696119,-0.031984803,-0.104700237,-0.077522355,1.375364729,2.330075134,-5.941827704,-5.975063469,-6.923966896,-6.212816643,-4.976660202,-5.62063131,-6.708227153,-3.150845674 -2827,P172W,0.002994454,-0.006930095,-0.021457196,-0.013916623,-0.276195727,-0.000691368,0.006030807,-0.0000419,-0.025062098,0.019369773,-0.033229962,0.002301173,-0.045215565,-0.003084136,-0.02474911,-0.207077048,-0.345314406,1.33877029,2.082277416,-10.16215466,-10.48194019,-12.54818049,-10.31205666,-8.907524437,-8.561071503,-9.458007638,-5.9335893 -2828,P172V,-0.029239919,-0.008407592,-0.004568361,-0.028244099,-0.097459969,0.043234017,-0.033917556,-0.024562281,0.03931267,-0.00798717,-0.008828014,-0.003608428,-0.005528294,0.012968047,-0.069456244,-0.071663629,-0.123256308,1.20163706,2.221100871,-6.088387538,-7.051690605,-6.695140991,-6.544233353,-4.257088974,-5.893783768,-7.076851192,-3.139617899 -2829,P172Y,-0.026845326,-0.042793402,-0.025758065,-0.042041594,-0.199544409,0.068970135,-0.017117611,-0.036573041,0.067677013,0.003911404,-0.089498207,0.017136231,-0.06865236,-0.035796611,-0.048286577,-0.18737374,-0.211715078,1.45179385,2.174120846,-8.503719482,-8.822316795,-11.73148089,-8.593373238,-6.683565475,-6.687861015,-7.368743381,-2.546249666 -2830,N173A,0.006717756,0.037353923,0.015937926,0.004064736,0.013932702,0.030829309,0.053005352,-0.03956984,0.015424618,0.057293893,0.017413953,-0.047528339,0.07940419,0.000709052,0.007420419,-0.029112952,0.056978355,1.349032761,2.537183893,-1.577549248,-1.936636597,-1.78372702,-1.173321899,-1.616831192,-1.37722953,-2.61833548,0.954854938 -2831,N173C,0.001439396,-0.021186905,0.005098947,0.00135119,-0.014365243,-0.032295283,-0.00448532,0.007364112,-0.032948717,0.018375827,-0.060749636,-0.035893272,0.046091166,-0.030368917,0.033071297,-0.053451128,0.024720643,1.308310082,2.407821952,-5.806904486,-5.884991966,-6.572581047,-5.845441872,-6.343238541,-4.388269005,-6.669226787,-3.839370534 -2832,N173E,0.007260559,-0.005198744,-0.024207679,-0.009863304,-0.008709017,-0.0036405,-0.006385892,0.020907009,0.016133178,-0.047982624,0.037585136,-0.073467091,0.025051734,-0.034399283,0.014672676,-0.043144978,0.025726945,1.414550562,2.455773264,-2.33825419,-2.512686981,-1.576178078,-2.488184563,-3.47100676,-1.643214569,-4.272080084,-0.380742051 -2833,N173D,-0.028956548,-0.007113008,-0.018001773,0.001731535,-0.029921061,-0.032295685,-0.057270647,-0.000642448,0.044087815,-0.002374712,-0.011851304,-0.01524408,-0.020759465,0.029530732,-0.026067662,-0.015468124,-0.044373997,1.216995399,2.621633422,0.325128186,0.77216433,-0.244569008,0.339980331,0.161853111,0.596212166,-2.139559444,0.274190508 -2834,N173G,0.009624825,-0.013039997,-0.00323681,-0.002602129,-0.001621661,-0.053431259,-0.010171811,0.02942146,0.029019919,-0.021075361,-0.005004632,-0.035354312,0.028880692,-0.019126617,0.01392236,-0.021595327,0.018352005,1.345368132,2.549826879,3.432091702,3.834842751,3.61705571,2.999996376,3.084715813,3.623847862,0.062596968,2.16086604 -2835,N173F,-0.065032233,-0.044671398,-0.018176517,-0.058276961,-0.024432157,0.018264583,-0.052821078,-0.077243388,0.082362744,0.024836834,-0.114179629,-0.008987913,-0.027365121,0.00209299,-0.118646912,0.018915325,-0.067779638,1.138968955,2.658352197,-5.21633231,-7.600942291,-5.173079926,-4.812976128,-4.361176155,-4.133487053,-5.189178868,-2.519573181 -2836,N173I,0.023717113,-0.005189174,-0.022162865,0.014634442,-0.314117936,0.072175004,0.048504119,-0.001069894,-0.048154616,-0.05589482,0.045516472,-0.030282081,-0.014043648,-0.003842791,0.033111674,-0.298942872,-0.329292999,1.564682548,2.074081493,-5.158388396,-4.04605407,-4.706553116,-6.16615654,-6.462567635,-4.410610619,-5.188377326,-0.532361682 -2837,N173H,-0.018152499,0.029554828,-0.005303441,-0.015475341,0.002965655,0.01376499,-0.033212343,-0.003092654,-0.016413853,0.104642955,-0.045533299,0.002822347,-0.013429228,0.010117134,-0.041067815,0.011759904,-0.005828594,1.166459095,2.648404694,-2.954143669,-3.857161118,-2.817829872,-2.537114326,-2.549466133,-3.009146896,-3.956380424,-1.701382281 -2838,N173K,-0.012951779,-0.031149081,0.008291035,0.008988504,-0.014792412,-0.023180697,-0.005920991,-0.019982566,0.010473746,-0.00499769,-0.057300471,-0.002366,0.01894807,0.019428552,-0.001451544,0.008688904,-0.038273727,1.264115617,2.776666739,-1.143728734,-0.405317787,-0.278602463,-0.999094185,-2.46672744,-1.568901794,-2.364962021,0.400786939 -2839,N173M,-0.030488914,-0.016288733,-0.000592062,-0.006250774,-0.054697623,0.002449613,-0.016958651,-0.044019177,-0.030854841,-0.002291797,-0.030285668,0.003543956,-0.00472808,-0.030949136,0.018447588,-0.066137294,-0.043257951,1.213159661,2.273230203,-6.629217696,-6.079475113,-5.860105843,-7.631908051,-7.460525597,-6.114073875,-5.477377975,-2.250224297 -2840,N173L,-0.015126919,-0.009105936,-0.022944468,-0.018635164,-0.030604266,-0.016878739,-0.009211185,-0.021042652,0.017450101,0.018084547,-0.036296418,-0.047634787,0.001745852,-0.02408399,-0.013186338,-0.037431812,-0.023776719,1.20233237,2.401994425,-4.301497604,-3.627875008,-4.105195282,-5.276047722,-5.534057434,-2.964312576,-3.58166368,-0.289016894 -2841,N173Q,-0.031887827,-0.008382269,-0.007088817,0.000729593,0.023715874,0.029596575,-0.043756562,-0.020019092,0.03804839,0.035858024,-0.052622561,0.010584621,-0.024762254,-0.013481101,0.014940287,-0.01873685,0.066168597,1.207256321,2.516790412,-3.631023184,-4.163015244,-2.365865685,-3.909438522,-4.804236595,-2.912559875,-4.385818965,-0.228309009 -2842,N173P,-0.02212302,-0.001234391,0.009059293,0.002747011,-1.716187143,0.495443483,-0.010301439,-0.0339446,-0.004613963,0.003117178,-0.005585959,-0.048739033,0.066857619,-0.012387494,0.017881516,-1.497526418,-1.934847867,0.66379259,1.319291736,-4.495989157,-4.750328377,-5.165717453,-4.331642296,-5.247192047,-2.985065613,-4.655447664,0.552280031 -2843,N173S,0.01982762,0.011568057,0.023774447,0.019108757,-0.000747788,-0.01700364,-0.003428385,0.043083625,0.016498937,0.017113987,0.006022127,-0.013227043,0.060775937,0.001522205,0.036695309,-0.043010846,0.041515271,1.414904449,2.54082215,-1.184478726,-1.098721489,-1.419968216,-1.659031593,-0.610461227,-1.134211105,-2.921137481,-0.405690245 -2844,N173R,0.019599032,0.021942557,0.024035294,-0.015800575,-0.050087137,-0.012407962,0.023468021,0.015730043,-0.002347408,0.023770678,0.020114436,-0.014398598,0.062469186,-0.02023669,-0.01136446,-0.095554241,-0.004620033,1.206623067,2.244273076,-3.525812575,-3.74708847,-2.801318329,-3.694113075,-4.858098671,-2.528444328,-3.807194379,0.232099791 -2845,N173T,0.015469235,-0.006757011,-0.010485862,-0.005613795,-0.027061775,-0.039670235,0.008124669,0.022813801,0.017541461,0.018315237,-0.031829258,-0.03524985,0.014278126,-0.039189443,0.027961854,-0.079821878,0.025698328,1.276815348,2.272848467,-2.079378719,-0.92025946,-2.566160385,-2.666741058,-2.447819695,-1.795912994,-3.324706793,-0.555265434 -2846,N173W,0.026021317,0.032000252,0.020948564,0.022435255,-0.004127451,-0.015243714,0.032901101,0.019141533,-0.02724949,0.038733973,0.025266531,0.015829975,0.026067153,-0.009690456,0.054560965,-0.021424036,0.013169134,1.238762276,2.562574386,-4.591917596,-5.531064194,-4.987632431,-3.976604988,-5.379947708,-3.084338661,-4.454155663,-0.988004727 -2847,N173V,-0.008661536,0.004203941,0.022232166,-0.005998165,-0.255777471,0.026388557,-0.018732144,0.001409073,-0.014895101,-0.005189509,0.013597391,-0.027048137,0.071512468,-0.036358243,0.024361913,-0.264609161,-0.24694578,1.530571657,2.001357715,-3.915617957,-1.373306343,-3.52046376,-4.880979568,-5.799297646,-4.004042465,-3.973026296,0.220842193 -2848,N173Y,-0.079363867,0.025983353,0.022069182,-0.002515225,0.017112284,0.015775837,-0.022957961,-0.135769773,0.014858209,0.065495825,-0.01352912,0.041286847,0.002851516,0.028284643,-0.033315092,-0.010042843,0.04426741,1.153400526,2.75274485,-4.031157385,-5.249492523,-4.06450106,-3.659955551,-3.428177773,-3.753660019,-4.713525265,-1.538049508 -2849,D174A,-0.052629167,0.003324744,-0.019212198,-0.75887084,-2.121400628,0.007686256,0.018223813,-0.123482147,-0.058473328,-0.00196796,0.008617447,-0.045184178,0.006759782,-0.507834937,-1.009906742,-2.097991022,-2.144810234,1.638249647,1.353995745,-10.72180954,-11.98618529,-11.0874538,-10.10832262,-9.611200455,-10.81588554,-6.749222704,-2.044681056 -2850,D174C,-0.14487539,0.031707962,-0.048474831,-0.012351426,-1.457901578,0.024806731,-0.126147839,-0.16360294,-0.038815783,0.091345199,-0.027929276,-0.059874285,-0.037075376,-0.00651857,-0.018184281,-1.621256896,-1.294546259,0.624152881,1.311173159,-15.31797137,-16.90184961,-16.13804378,-13.63742892,-14.49939695,-15.41313757,-8.898604022,-3.653369246 -2851,D174E,-0.042995964,0.05843266,-0.017634674,-0.006814221,-0.712773759,0.109284701,-0.000429879,-0.085562048,-0.032331414,0.083670847,0.033194473,-0.027934529,-0.007334818,-0.010541959,-0.003086483,-0.575847137,-0.849700381,0.860021519,1.458078294,-6.850690947,-8.231850166,-8.379272308,-5.904459877,-5.553889221,-6.183983162,-5.93359849,-1.817969274 -2852,D174G,-0.05122339,0.028650339,0.002101644,-0.190435789,-1.960745279,0.008787521,0.001416858,-0.103863637,-0.047534171,0.037825601,0.019475077,-0.009307786,0.013511074,-0.112855258,-0.268016319,-1.684335368,-2.23715519,0.928335394,1.32552305,-10.7345986,-11.72497608,-13.26781647,-11.3823937,-8.288051575,-9.009755188,-5.957762258,-0.788055044 -2853,D174F,-0.121080189,0.002685033,-0.510628104,-1.781082166,-2.899982662,0.005956688,-0.090312717,-0.151847661,-0.070098088,0.059261541,-0.053891475,-0.27968969,-0.741566518,-1.688549126,-1.873615205,-2.574595567,-3.225369756,1.323239017,0.749759396,-17.31291887,-18.41995615,-20.33129092,-14.99844891,-13.5995023,-19.21539608,-8.260778515,-3.916737587 -2854,D174I,-0.060031986,0.04373365,-0.042478711,-1.767508024,-2.551690557,0.076786745,0.023200632,-0.143264603,-0.057860583,0.0431468,0.044320499,-0.067198841,-0.01775858,-1.51627307,-2.018742978,-2.377495927,-2.725885187,0.788683698,0.708708457,-14.82132415,-16.29657623,-17.45395241,-13.54354298,-12.28734844,-14.52520071,-8.6026152,-4.962971945 -2855,D174H,-0.008465674,0.035613992,0.029013144,-1.493665621,-2.623160767,0.025922514,-0.014194878,-0.00273647,-0.059021507,0.029850462,0.041377521,-0.024571614,0.082597901,-1.205178922,-1.78215232,-2.334263412,-2.912058122,1.024948377,0.774056606,-13.42042128,-15.1160162,-14.30366535,-13.77900986,-10.4713991,-13.43201588,-8.940356751,-4.78260309 -2856,D174K,-0.11881668,0.042919613,-0.393902232,-1.886997904,-2.962412655,0.048693848,-0.040677891,-0.196955468,-0.081535836,0.07299053,0.012848695,-0.198611228,-0.589193236,-1.528753655,-2.245242153,-2.389976512,-3.534848797,1.204553149,0.756009348,-12.08782319,-12.85727001,-14.9228683,-12.20642,-10.30637704,-10.14618062,-7.740219294,-3.769324607 -2857,D174M,-0.10060737,0.009207077,-0.023731243,-1.324841251,-2.842131669,-0.008027923,-0.052720333,-0.148494407,-0.021529929,0.016310466,0.002103688,-0.050189852,0.002727367,-0.871632274,-1.778050228,-2.451796216,-3.232467122,1.017395755,0.836546245,-14.63039694,-14.82352807,-17.30967104,-13.18460075,-11.62433072,-16.20985413,-8.139779653,-4.486792331 -2858,D174L,-0.065937696,0.034121741,-0.002635099,-1.798651445,-2.590402136,0.023881524,-0.030506029,-0.101369363,-0.054496544,0.062456752,0.005786729,0.013274433,-0.018544631,-1.494513623,-2.102789266,-2.322568117,-2.858236155,-0.020622953,0.683024565,-13.40808023,-14.27438631,-17.23506212,-12.21390413,-8.933121086,-14.38392751,-7.79682329,-3.317974661 -2859,D174N,-0.12302409,0.006339142,-0.038943864,-0.054175147,-2.324862848,0.043555288,-0.026408582,-0.219639598,-0.101102369,0.036782956,-0.024104672,-0.03869449,-0.039193238,-0.053868313,-0.054481981,-1.911499819,-2.738225877,0.885794831,1.307908979,-8.112277916,-9.358982574,-7.574041458,-7.766176125,-8.592784569,-7.269404854,-6.23158537,-3.115299993 -2860,D174Q,0.001966151,0.053777371,0.012006858,-0.011301994,-2.490967543,0.034189321,-0.014093236,0.018025538,-0.077660242,0.087445184,0.020109557,0.007728953,0.016284763,0.005846175,-0.028450162,-1.757667599,-3.224267486,0.473835437,1.30135375,-12.04189703,-15.05711369,-12.87870181,-11.01854622,-10.33882002,-10.91630344,-6.812272249,-1.776225609 -2861,D174P,-0.03251293,0.024434311,-1.108504614,-2.094969647,-3.314416907,0.060837423,0.031681674,-0.096707533,-0.060850844,0.024807843,0.024060778,-1.002557797,-1.214451431,-2.098431038,-2.091508256,-2.770597659,-3.858236155,0.692873078,0.117770252,-13.79912807,-16.70872829,-14.41170055,-13.1364435,-11.00756654,-13.73120151,-7.357471913,-3.59882789 -2862,D174S,-0.085677333,0.035044849,-0.015640083,0.00855648,-1.527444944,0.104100545,-0.045088948,-0.126265717,-0.042696326,0.045241312,0.024848385,-0.012585199,-0.018694967,0.015323951,0.001789009,-1.558584613,-1.496305274,0.699755616,1.318380491,-11.29878411,-13.99638942,-11.1249553,-10.46778622,-11.21910447,-9.685685127,-6.383975679,-2.304830747 -2863,D174R,-0.028739273,0.030905215,-0.673220278,-1.900896381,-3.00426622,0.010353586,0.01353992,-0.071018465,-0.048604733,0.032033419,0.02977701,-0.42173279,-0.924707765,-1.802810526,-1.998982235,-2.413381076,-3.595151364,1.61656737,0.789696553,-12.95140664,-14.89354681,-15.53130252,-14.29268494,-9.473947357,-10.56555155,-7.097927007,-2.39717509 -2864,D174T,-0.085681779,0.023085966,0.006709983,-0.602217559,-2.456080174,0.040680047,-0.013226697,-0.15813686,-0.044922271,0.049807909,-0.003635978,-0.029384903,0.042804869,-0.284968071,-0.919467046,-1.875021956,-3.037138391,1.351548306,1.346736471,-11.61514034,-13.79932217,-13.16772493,-10.32089631,-9.042235359,-11.7455229,-6.516578542,-2.429377386 -2865,D174W,-0.065688432,0.003438618,-0.829227068,-2.085911512,-3.101784767,0.013990912,-0.034423651,-0.096953213,0.004511703,-0.003894104,0.010771339,-0.527036315,-1.131417821,-1.855585,-2.316238024,-2.507548234,-3.696021299,1.703817929,0.795774579,-16.33919035,-18.16587011,-17.91834765,-15.34762374,-13.49255187,-16.77155839,-9.16027713,-5.570763137 -2866,D174V,-0.107161808,0.002036564,-0.036421864,-1.473654375,-2.717493608,0.019101382,-0.041259022,-0.173064594,-0.053902593,0.014525455,-0.010452328,-0.026921307,-0.04592242,-1.007927867,-1.939380883,-2.31994304,-3.115044175,0.823624515,0.771784869,-14.06362061,-15.68441897,-16.11815984,-12.93904907,-11.38807688,-14.18839827,-8.271656587,-4.240862203 -2867,D174Y,-0.109499537,-0.005627213,-0.296041971,-2.311744967,-2.725558231,0.028563421,-0.028472921,-0.190526152,-0.050086654,-0.003662603,-0.007591822,-0.152966273,-0.439117668,-1.933356197,-2.690133736,-2.284289437,-3.166827024,1.122447296,0.686400881,-16.93467668,-18.80760307,-20.2577144,-14.70762085,-13.47006979,-17.43037528,-8.835744072,-2.590810884 -2868,E175A,-0.023573853,-0.016242182,0.020863976,0.025225471,-0.050278436,0.041145537,-0.077638868,0.030491163,0.043845836,0.005261324,-0.037745688,-0.005516729,0.047244681,0.02871346,0.021737481,-0.041828979,-0.058727892,1.312577676,2.553003902,-2.408082179,-2.17261647,-2.252398941,-2.175702911,-3.133446915,-2.306245659,-3.261160434,-1.191461162 -2869,E175C,0.013717798,-0.014984208,-0.030447694,-0.019242896,-0.115690451,0.075216558,-0.000332937,0.027768533,0.061553884,0.000954178,-0.030922594,-0.058915536,-0.001979852,0.00798784,-0.046473631,-0.070737669,-0.160643232,1.24745667,2.356838983,-7.926379904,-7.830895592,-7.026179115,-8.544173714,-8.847645424,-7.383005676,-7.856329223,-4.092048968 -2870,E175D,-0.076617398,-0.0000269,-0.016089655,-0.030750039,-0.100610422,0.072441241,-0.120969807,-0.032264988,0.051016942,0.031624782,-0.031678554,-0.0027455,-0.029433809,-0.006558662,-0.054941416,-0.005168624,-0.196052219,1.245981066,2.677609437,-2.983296437,-2.645641411,-2.786388657,-3.155836891,-3.245169861,-3.083445366,-4.784790539,-1.137091138 -2871,E175G,-0.06587765,-0.050816919,-0.023361973,-0.025041321,-0.280954368,0.050455604,-0.098050026,-0.033705274,0.037089464,-0.002914609,-0.098719228,-0.0109958,-0.035728146,-0.001636574,-0.048446067,-0.223948561,-0.337960175,1.201525363,1.93779228,-5.573690318,-6.443444168,-4.412306511,-6.338917885,-6.641439957,-4.032343071,-6.13639156,0.270719887 -2872,E175F,-0.045212979,-0.040929692,-0.010700589,-0.021737995,-0.140403233,0.028848342,-0.120606002,0.030180045,0.019270782,-0.005088418,-0.076770966,-0.02277923,0.001378052,-0.041955785,-0.001520204,-0.139327851,-0.141478614,1.488534738,2.279591948,-7.36818071,-7.689630188,-5.958109451,-7.569274269,-9.008226517,-6.615663124,-6.479535997,-0.808225119 -2873,E175I,-0.001265046,-0.041455608,-0.036920166,0.010638908,-0.070853735,0.025260346,-0.027684461,0.025154369,0.038113526,0.011070348,-0.093981563,0.025107019,-0.09894735,0.062070406,-0.04079259,0.018651768,-0.160359237,1.076833718,2.62284945,-3.226594325,-3.9229702,-3.191520424,-3.279470711,-3.569692497,-2.169317795,-4.805841631,-0.467299363 -2874,E175H,-0.106882981,0.016259187,-0.030562039,-0.000954739,-0.070252314,0.037388245,-0.134146913,-0.079619049,0.041094934,0.05895549,-0.026437116,0.031693981,-0.092818058,0.047751959,-0.049661436,0.013262804,-0.153767432,1.21664648,2.720926035,-7.860020764,-7.389723061,-6.588069534,-8.686639809,-9.069827164,-7.565844254,-6.98197814,-1.601440502 -2875,E175K,-0.050887752,-0.010827625,0.008479525,-0.002565873,-0.094820258,0.040425428,-0.060680845,-0.041094659,0.053798999,0.046524259,-0.068179509,0.04163954,-0.02468049,0.051135585,-0.05626733,-0.049495742,-0.140144773,1.344604634,2.553957834,-2.571526772,-2.526330353,-2.510010086,-2.58175396,-2.477536705,-2.762002754,-3.988821562,-0.405303067 -2876,E175M,0.005580649,0.02554158,0.006446594,-0.001826571,-0.065348191,0.0500999,-0.017150891,0.028312188,0.048871498,0.077605506,-0.026522346,0.072138188,-0.059245,0.023951855,-0.027604997,0.019600532,-0.150296913,1.135845715,2.60945077,-4.705581284,-5.129372704,-4.95989579,-4.184471237,-4.863535187,-4.3906315,-5.949827239,-2.163344423 -2877,E175L,-0.042696058,-0.054942569,-0.017258676,-0.020633989,-0.077029978,0.023793559,-0.065295929,-0.020096186,0.053199697,-0.016991427,-0.092893711,0.027417737,-0.061935089,0.001768872,-0.043036849,-0.027458191,-0.126601765,1.276755325,2.520657352,-2.341291339,-2.780376762,-2.828326935,-1.539412964,-2.882130959,-1.676209076,-4.031069281,0.092686069 -2878,E175N,-0.031020645,-0.010699658,-0.036052543,-0.020251115,-0.118612428,0.006077944,-0.063020559,0.00097927,0.019345913,0.019697643,-0.041096959,-0.044050646,-0.028054439,-0.014590758,-0.025911472,-0.11465836,-0.122566496,1.471319598,2.341975392,-5.386352328,-4.9748358,-5.178721466,-5.810367546,-5.944981354,-5.022855476,-5.529574469,-1.517473863 -2879,E175Q,-0.032596096,-0.048933727,-0.027570451,-0.03616869,-0.076423817,-0.019463694,-0.055277954,-0.009914238,0.04569701,-0.004469597,-0.093397856,-0.028625969,-0.026514933,-0.007586883,-0.064750496,-0.011139013,-0.141708621,1.193999535,2.453429491,-3.777950479,-3.383546555,-4.148035339,-3.91202449,-3.969509132,-3.476636879,-4.920014093,-1.633321715 -2880,E175P,-0.027726449,-0.023185427,-0.017261061,-0.005796712,-0.04213872,0.005935785,-0.067434976,0.011982079,0.03433395,0.013714965,-0.060085819,-0.005608007,-0.028914114,0.02441245,-0.036005873,0.014872564,-0.099150004,1.207911703,2.739397172,-0.709166814,-0.546736107,0.091913986,-0.349050102,-3.387084854,0.645123009,-2.668306264,0.88450424 -2881,E175S,-0.029040106,-0.018085041,-0.011261408,-0.007345385,-0.08198592,0.040974413,-0.063455861,0.005375649,0.031119588,0.014804102,-0.050974184,0.026724381,-0.049247196,0.028694716,-0.043385485,-0.01784204,-0.146129799,1.186105176,2.606534576,-4.650903201,-5.249678299,-4.200985237,-4.988620514,-4.91926683,-3.895965126,-6.288125755,-1.904633836 -2882,E175R,-0.003664968,-0.025145623,-0.020167833,-0.01518402,-0.167412478,0.024712261,-0.039506295,0.032176359,0.017854449,0.013420989,-0.063712235,-0.017100436,-0.02323523,0.007041762,-0.037409802,-0.121874493,-0.212950463,1.51618479,2.407883191,-5.043027803,-4.702225845,-4.693409698,-5.37234581,-5.750666138,-4.696491524,-5.668445932,0.159446341 -2883,E175T,-0.049302415,-0.064397945,-0.033498009,-0.020719706,-0.106713349,0.043368414,-0.112399067,0.013794237,0.057213192,-0.031396573,-0.097399316,-0.013700644,-0.053295374,0.01344031,-0.054879722,-0.033051302,-0.180375396,1.537094526,2.782064661,-4.250708009,-4.573365196,-3.996172112,-4.150927811,-5.47210939,-3.060965538,-5.302403676,-0.658955582 -2884,E175W,-0.028465358,-0.027556099,-0.017018591,0.010367648,-0.094118681,0.02304429,-0.07840261,0.021471895,0.075198544,0.014235245,-0.069347442,0.00784658,-0.041883762,0.033199071,-0.012463775,-0.031959226,-0.156278135,1.234983777,2.523943991,-9.056844386,-9.010469368,-7.737675606,-9.746597748,-10.3212368,-8.468242409,-7.411446278,-3.400354944 -2885,E175V,-0.013857552,-0.051942446,-0.02632217,-0.01390373,-0.076902895,0.042646736,-0.041868388,0.014153284,0.073395173,-0.032441188,-0.071443703,-0.032431154,-0.020213185,-0.002121189,-0.025686271,-0.034044138,-0.119761652,1.265448124,2.439184837,-1.456077205,-0.911000801,-1.56192775,-1.302009056,-2.232738197,-1.27271022,-3.12519391,-0.360532869 -2886,E175Y,-0.129098959,-0.057639795,-0.049609427,-0.020388089,-0.109305066,0.066133737,-0.138017212,-0.120180706,0.010515573,0.005197638,-0.120477228,0.011034663,-0.110253517,0.033250793,-0.07402697,-0.000569887,-0.218040244,1.130303773,2.484304809,-8.087906705,-8.679746597,-6.101220177,-9.16758889,-8.224896843,-8.266081017,-6.2237845,-0.096125799 -2887,R176A,-0.071857298,-0.026350661,-0.060884604,-0.047761581,-0.855971986,0.180609636,-0.076465699,-0.067248896,0.044583799,-0.026169121,-0.0265322,-0.053905919,-0.067863288,-0.041319787,-0.054203375,-0.746472037,-0.965471934,1.054332027,1.480085921,-11.19985853,-11.74871239,-11.42112824,-11.19811203,-9.601659721,-12.02968026,-6.957355057,-2.076338752 -2888,R176C,0.081896215,0.099546566,0.104517165,0.081055122,-0.592263614,0.067848929,0.06304145,0.10075098,0.093343891,0.110087223,0.089005908,0.090797261,0.118237069,0.090943628,0.071166615,-0.476471638,-0.70805559,1.211113039,1.684792244,-12.6104972,-12.71686913,-12.58791218,-13.00278628,-11.51872523,-13.2261932,-8.426318326,-5.57589878 -2889,R176E,-0.117725967,0.002897525,0.014373545,-0.055572548,-1.282004161,0.186238877,-0.118580635,-0.116871299,0.016458605,0.020077149,-0.0142821,-0.029786429,0.058533519,-0.073014821,-0.038130274,-1.36727279,-1.196735532,0.887806359,1.345681966,-11.72385191,-13.81853106,-11.33221478,-11.10415488,-10.78763503,-11.5767238,-6.969477724,-1.631472208 -2890,R176D,0.043977391,0.046168442,-0.042369194,-0.094755875,-1.773480238,0.079257619,0.065327048,0.022627733,-0.00680394,0.046136279,0.046200605,-0.065179778,-0.019558609,-0.042928201,-0.146583548,-2.05463958,-1.492320895,0.820552964,1.297180087,-13.03739702,-15.60400839,-13.91822433,-12.09697907,-11.39557787,-12.17219541,-6.152511783,-1.796460224 -2891,R176G,-0.063106391,-0.022211584,-0.048380919,-0.019576468,-1.789170972,0.063134692,-0.067576614,-0.058636167,0.019344687,0.001609837,-0.046033005,-0.055206884,-0.041554953,-0.020162786,-0.018990149,-1.677332825,-1.901009119,0.466340995,1.303002185,-12.25653717,-12.49552354,-12.97960055,-12.48998045,-11.01876628,-12.29881505,-7.704117196,-3.464066663 -2892,R176F,-0.078119647,-0.012283504,-0.037038031,-0.074999277,-1.1687866,0.111451446,-0.025873397,-0.130365897,0.008647051,0.069672318,-0.094239326,0.025771687,-0.099847749,-0.009968683,-0.14002987,-0.771802589,-1.565770611,0.829547367,1.411312852,-14.59949924,-15.35678038,-14.62412141,-13.87090638,-11.5357986,-17.60988942,-7.86649232,-4.433807142 -2893,R176I,-0.064868218,-0.025724652,0.024929708,-0.134505508,-2.562807203,0.053181804,-0.027513064,-0.102223371,-0.060774358,-0.099329099,0.047879795,-0.050975728,0.100835144,-0.103749438,-0.165261578,-2.291552076,-2.834062329,0.969561498,1.277405341,-14.39259583,-14.72611429,-15.62384715,-15.10842486,-9.918622169,-16.58597068,-8.268505776,-3.480571081 -2894,R176H,-0.065217183,-0.007553497,-0.001812962,-0.049010597,-0.693165748,0.084917602,-0.054914179,-0.075520186,0.020895689,0.007942404,-0.023049398,-0.045968682,0.042342758,-0.061493344,-0.036527849,-0.517046005,-0.86928549,1.759346656,2.020303871,-7.28690563,-8.586422691,-7.138146606,-6.891790604,-7.280798775,-6.537369476,-6.114816599,-3.685320462 -2895,R176K,-0.060087168,-0.056300399,-0.039740914,-0.092763737,-0.250014334,-0.070662839,-0.070374157,-0.049800179,0.135569027,-0.025150391,-0.087450406,0.046887731,-0.126369558,-0.071860293,-0.11366718,-0.158013168,-0.3420155,1.452999002,2.223525207,-8.478686736,-10.51901148,-8.710116287,-8.352342339,-7.075342804,-7.736620766,-6.029048124,-2.829217665 -2896,R176M,-0.07452096,-0.04296967,-0.050676895,-0.016271566,-0.688151548,0.200877917,-0.08569246,-0.063349459,0.209169722,-0.074523659,-0.01141568,-0.06338978,-0.037964009,-0.033254371,0.000711239,-0.392349386,-0.98395371,1.243076001,1.748497349,-13.2891803,-13.66903976,-13.46973713,-14.53101938,-9.737071251,-15.039034,-7.592053854,-4.278713403 -2897,R176L,-0.096856507,-0.033694548,-0.020470089,-0.052466595,-0.760679487,0.137558155,-0.088995025,-0.104717988,-0.013131368,0.0221601,-0.089549196,-0.024171614,-0.016768564,-0.018793781,-0.086139409,-0.60958179,-0.911777184,0.896348162,1.467057688,-9.890960172,-9.530928482,-10.01421451,-12.15523392,-5.55966449,-12.19475946,-6.11180845,-2.045677242 -2898,R176N,-0.002351286,-0.006509551,-0.011815973,-0.006562267,-0.755379623,0.120316101,0.049573357,-0.054275929,-0.029175372,0.03071047,-0.043729572,0.02260164,-0.046233586,0.008706603,-0.021831136,-0.553123887,-0.957635359,0.708140476,1.428685603,-12.2575676,-14.58612895,-13.07768082,-11.68727044,-11.53003071,-10.4067271,-7.332763013,-2.222054641 -2899,R176Q,0.002410165,-0.033840691,-0.037146004,-0.028296515,-0.097072605,0.034658844,0.006677075,-0.001856745,0.01608072,-0.042288591,-0.02539279,-0.076152514,0.001860507,-0.011040685,-0.045552345,-0.166583897,-0.027561312,1.480708952,2.244304579,-6.99205938,-7.715565514,-6.932929855,-6.685892288,-6.189306549,-7.436602692,-5.47673551,-2.497989822 -2900,R176P,-0.051587142,-0.015072617,-0.008273108,-1.719784272,-2.901193523,0.00449049,-0.037396287,-0.065777997,-0.002902398,0.0000364,-0.030181633,-0.023411243,0.006865027,-1.507548716,-1.932019827,-2.567865429,-3.234521617,0.687152211,0.703487054,-12.50421708,-12.31322327,-11.40193111,-14.58711528,-10.66496048,-13.55385524,-7.872245032,-3.606730136 -2901,R176S,-0.02843112,-0.004567522,-0.025602594,0.001998315,-0.660139414,0.291414187,-0.039150459,-0.01771178,-0.041477825,-0.007555476,-0.001579567,-0.02482301,-0.026382177,0.005701093,-0.001704464,-0.493077651,-0.827201177,0.858785436,1.494811167,-11.41301496,-11.63341774,-10.81336767,-11.84196874,-10.43382599,-12.34249464,-6.11452491,-2.666307065 -2902,R176T,-0.042435185,-0.019027479,-0.014098273,-0.060936251,-2.210755806,0.062656245,-0.031759347,-0.053111023,0.012096114,-0.006081823,-0.031973135,-0.052582805,0.02438626,-0.002329576,-0.119542925,-1.665677082,-2.755834529,0.578072086,1.308581815,-13.63722695,-12.65398789,-14.43475518,-13.76278414,-12.76957018,-14.56503735,-6.19954912,-1.277153737 -2903,R176W,-0.101783992,-0.025738565,-0.034434598,-0.06049273,-1.425390569,0.0079184,-0.109893493,-0.093674491,0.021248077,0.013205257,-0.064682386,0.00052512,-0.069394315,-0.021232731,-0.099752728,-1.414016194,-1.436764943,0.681291911,1.322644984,-13.12296577,-12.65916666,-14.40130931,-13.46072641,-10.74812091,-14.34550555,-7.871908125,-2.745484314 -2904,R176V,-0.088851873,0.005675449,-0.02162835,-0.001205772,-2.112091666,0.085513641,-0.055084439,-0.122619307,0.037619699,0.072465218,-0.061114321,0.038838839,-0.082095539,0.035709838,-0.038121382,-1.559372836,-2.664810495,0.719369325,1.317873495,-13.49466811,-13.84304639,-15.32251915,-14.51787228,-9.483109909,-14.30679281,-7.399867729,-3.264252615 -2905,R176Y,-0.025176067,-0.021198977,-0.035533687,-0.048669883,-1.119486404,0.054994415,-0.030569507,-0.019782627,0.005507186,0.045658139,-0.088056092,-0.060970892,-0.010096481,-0.005130082,-0.092209684,-0.908293141,-1.330679666,0.866835732,1.391633495,-13.44342972,-14.99558603,-14.22862951,-12.56653098,-12.27742448,-13.14897758,-7.867198952,-3.737393301 -2906,D177A,-0.016120823,-0.24444147,-1.853532287,-2.13614782,-2.777766007,-0.042933256,-0.005626037,-0.026615608,-0.007144463,-0.144132112,-0.344750827,-1.820313279,-1.886751295,-1.874339039,-2.3979566,-2.372839283,-3.182692731,0.730343941,-0.041195301,-14.29781639,-12.32993608,-13.92959061,-13.73057261,-14.12534537,-17.37363729,-7.511382193,-4.475968388 -2907,D177C,-0.03384615,-0.010968565,-0.042513662,-1.951271572,-3.206833111,0.035554673,-0.043325575,-0.024366724,0.012332127,-0.001311963,-0.020625167,0.011560291,-0.096587614,-1.632887153,-2.26965599,-2.84739074,-3.566275482,0.676165595,0.695076903,-16.71855757,-16.12085495,-17.20444671,-15.527494,-16.35352685,-18.38646533,-7.996072771,-5.265084093 -2908,D177E,0.031810139,-0.142519666,-1.357793032,-1.898211186,-2.887131973,-0.045634199,0.036019088,0.02760119,0.02799369,-0.100624641,-0.18441469,-1.448476073,-1.26710999,-1.73411042,-2.062311952,-2.274003349,-3.500260596,3.751052051,2.226345549,-12.98444365,-12.56549814,-12.33393907,-11.69905081,-12.6254398,-15.69829041,-10.38001803,-9.881647741 -2909,D177G,-0.05066527,-0.019145343,-1.550380212,-2.474242629,-3.096966536,0.403053565,-0.044590772,-0.056739767,-0.005068237,-0.040202634,0.001911948,-1.629233626,-1.471526798,-2.035441904,-2.913043354,-2.834972143,-3.358960928,0.984896232,0.001689835,-13.86645578,-11.76493343,-13.79533993,-12.87650214,-13.902781,-16.99272241,-7.157390032,-2.375771504 -2910,D177F,-0.040112678,-1.45863092,-2.239600152,-2.703804636,-2.845422823,0.086758748,-0.031420254,-0.048805102,0.046116649,-1.707865145,-1.209396695,-2.063900026,-2.415300278,-2.214835799,-3.192773473,-2.315396034,-3.375449612,-0.324851548,-1.03246806,-19.30167021,-18.54223775,-20.15716284,-17.19859063,-19.46637615,-21.14398369,-9.564736308,-7.424561439 -2911,D177I,-0.039547798,-1.407181644,-2.173694409,-1.885323903,-2.978487084,-0.029232759,-0.032159136,-0.046936459,0.033557843,-1.268532451,-1.545830836,-2.101688587,-2.24570023,-1.951594364,-1.819053442,-2.65421459,-3.302759577,0.260260037,-0.764645402,-18.84272683,-18.46856734,-18.72485277,-17.70716441,-17.28675867,-22.02629095,-8.346648431,-6.332585614 -2912,D177H,-0.0574232,-1.347642099,-2.470607755,-2.42421759,-3.226945425,0.00061601,-0.057239312,-0.057607088,0.048422024,-1.393709222,-1.301574976,-2.3295277,-2.61168781,-2.304372214,-2.544062965,-2.882053704,-3.571837145,-0.332672123,-0.902037139,-13.38927967,-12.34057926,-12.62737952,-11.48412038,-13.46533062,-17.02898856,-6.862055389,-5.009457529 -2913,D177K,-0.076134552,-1.651551649,-2.235122516,-2.670331026,-2.962464211,-0.027912485,-0.058461189,-0.093807914,-0.012706102,-1.464758547,-1.83834475,-2.325943406,-2.144301625,-2.175849184,-3.164812868,-2.577439414,-3.347489008,-0.042119871,-0.931412756,-19.10434258,-17.07863573,-20.78290244,-18.44397006,-17.88225241,-21.33395224,-10.2235114,-9.090818499 -2914,D177M,-0.037824157,-1.631384144,-1.881562351,-2.607206207,-2.748824394,0.285960998,-0.019709687,-0.055938626,-0.055307599,-1.809139963,-1.453628324,-1.670324823,-2.092799878,-2.5202306,-2.694181814,-2.620790835,-2.876857953,-0.469384865,-1.116083105,-18.96438576,-18.42030879,-19.45063929,-18.54661929,-17.26363905,-21.14072237,-8.807471548,-6.75638626 -2915,D177L,0.007256453,-1.478178075,-2.121342147,-2.519836198,-3.036515649,0.004879856,0.007511955,0.007000951,0.002233388,-1.535704179,-1.420651971,-2.046641021,-2.196043272,-2.088432324,-2.951240072,-3.143235068,-2.929796229,-0.150182889,-0.971961803,-18.68623285,-17.79818128,-20.19349654,-17.64153305,-16.67184169,-21.12611169,-8.152707216,-6.072712942 -2916,D177N,-0.017075801,-0.000158119,0.020908438,-2.070950394,-3.039174838,0.51936255,-0.034688993,0.000537392,-0.009583795,-0.053688603,0.053372366,0.003091077,0.038725798,-1.666358636,-2.475542151,-2.72116138,-3.357188295,0.581048226,0.686829747,-9.327629109,-8.96271405,-8.139175438,-9.654137802,-8.485027817,-11.39709044,-5.162531784,-0.089085383 -2917,D177Q,-0.029995821,-1.198458333,-2.06711849,-2.406384237,-2.999547418,0.002064553,-0.028396279,-0.031595363,0.045269245,-1.288324378,-1.108592287,-1.614396036,-2.519840943,-2.54348306,-2.269285414,-2.644043294,-3.355051541,2.718566902,0.6131567,-16.24939426,-15.58312479,-16.40857986,-14.11960248,-17.36409329,-17.77157085,-8.388554693,-6.072712743 -2918,D177P,-0.054703996,-1.630859863,-2.136533618,-2.232994683,-2.955764358,0.017016641,-0.034895108,-0.074512884,-0.042048714,-1.787894622,-1.473825104,-2.158169943,-2.114897293,-1.911165707,-2.554823658,-2.58575721,-3.325771505,-0.223047351,-1.087294807,-16.71263022,-16.22572065,-17.16447638,-15.55302508,-16.1109048,-18.50902417,-7.792280456,-4.629567453 -2919,D177S,-0.040726507,-0.071354996,-1.413753023,-2.164127034,-3.044305848,0.004625543,-0.038938469,-0.042514545,-0.033411471,-0.057048655,-0.085661336,-1.456624426,-1.37088162,-1.94998288,-2.378271187,-2.624574383,-3.464037313,2.76557031,1.203364473,-14.02711028,-12.70172464,-14.80113695,-12.58582555,-12.76977471,-17.27708955,-6.590139751,-2.906208201 -2920,D177R,-0.040080099,-1.58093661,-2.069675444,-2.329563343,-3.254302042,0.026025868,-0.025559634,-0.054600563,0.008478657,-1.691854191,-1.470019029,-1.854069046,-2.285281842,-2.067152726,-2.59197396,-2.804535058,-3.704069025,-0.555157375,-1.06493945,-15.28279183,-15.03369551,-14.8687896,-14.6361579,-15.15395259,-16.72136355,-8.268776969,-5.669493051 -2921,D177T,-0.037308838,-0.889491313,-2.241938641,-2.531019115,-3.24570132,0.00433985,-0.025310124,-0.049307551,0.038496493,-0.860049115,-0.91893351,-2.194720945,-2.289156336,-1.898498686,-3.163539543,-3.145186957,-3.346215683,0.835632919,-0.533736591,-15.52140162,-14.15837387,-16.6662601,-14.83309168,-14.50199335,-17.44728909,-7.483252257,-3.12611923 -2922,D177W,-0.004003598,-1.293930152,-2.227542097,-2.512235609,-3.193444419,-0.082693571,-0.01816347,0.010156274,0.092009779,-1.442169072,-1.145691231,-2.284870526,-2.170213667,-2.310867562,-2.713603655,-2.712457792,-3.674431045,-0.116619183,-0.898743893,-19.05736052,-18.10889854,-18.69110889,-17.70557104,-19.22812548,-21.55309866,-10.38829928,-9.900579668 -2923,D177V,-0.004413096,-1.392795112,-2.251957696,-2.273133856,-3.264237045,0.013170095,0.00565829,-0.014484481,0.015897236,-1.473721287,-1.311868937,-2.145026603,-2.358888788,-2.074113627,-2.472154084,-2.697552607,-3.830921483,-0.007956959,-0.925310894,-17.61909881,-17.15531444,-17.31167806,-17.08289298,-15.96140543,-20.58420312,-8.600667907,-6.357603389 -2924,D177Y,-0.026625223,-1.440494156,-1.573095255,-2.651457135,-2.381120951,0.26567847,-0.035415303,-0.017835142,0.03599238,-1.652461745,-1.228526567,-1.610556618,-1.535633891,-2.129469176,-3.173445093,-2.008180661,-2.754061241,4.151501698,1.881614181,-19.24181579,-18.29333009,-20.33169232,-16.84428907,-19.51461633,-21.22515112,-10.1963139,-9.092938945 -2925,T178A,-0.03697258,-0.01025819,-0.059297559,-0.666725184,-2.022396221,-0.067034385,-0.03186832,-0.042076839,0.000912627,-0.052362275,0.031845895,-0.09463138,-0.023963738,-0.314931378,-1.018518989,-1.784820715,-2.259971726,1.496210128,1.388526479,-7.502510542,-7.013764389,-7.761388725,-6.662048882,-8.340127289,-7.735223427,-7.22138722,-2.695679955 -2926,T178C,-0.003452309,0.022467565,-0.006093559,0.026023947,-1.675433092,-0.045349138,0.010440386,-0.017345003,-0.049738375,-0.014416,0.059351129,-0.06807876,0.055891643,0.016239738,0.035808156,-1.47370052,-1.877165663,0.824484043,1.331275808,-10.4921316,-9.741372475,-12.29367126,-9.133995049,-10.94033076,-10.35128847,-8.811347112,-5.556098323 -2927,T178E,-0.016937157,-0.000344385,-1.103886423,-2.109838908,-2.343746274,-0.071994275,-0.012741378,-0.021132935,0.092723983,-0.050796901,0.050108132,-0.883137062,-1.324635783,-1.72250317,-2.497174646,-2.326105167,-2.361387381,3.059225959,1.758831309,-11.75023141,-11.15071449,-12.37046675,-10.2852391,-13.60105926,-11.34367744,-8.027812092,-3.564414251 -2928,T178D,-0.022743939,-0.078639435,-0.868232429,-1.976704964,-2.863717584,-0.039652777,0.004836025,-0.050323902,-0.002807432,-0.113262539,-0.04401633,-0.606403739,-1.130061118,-1.715872591,-2.237537336,-2.962927265,-2.764507903,1.989588289,0.944588612,-13.413218,-12.50605766,-15.38231866,-11.48832662,-14.96376373,-12.72562331,-9.296412006,-5.612057393 -2929,T178G,-0.03650891,-0.028961538,-0.169189954,-1.741481884,-2.549241462,-0.073484506,-0.032556597,-0.040461223,0.035529476,-0.074400118,0.016477042,-0.185431521,-0.152948387,-1.474804602,-2.008159165,-2.593316415,-2.505166509,1.273035993,0.778656743,-7.316514032,-7.403198471,-6.319113762,-7.155837547,-6.944204147,-8.760216232,-7.20122836,-3.217917593 -2930,T178F,0.019355587,0.038974695,-1.042183748,-1.979926957,-2.86912198,-0.090820779,0.068454157,-0.029742983,0.120552538,0.068932419,0.00901697,-0.704019348,-1.380348148,-1.765234206,-2.194619707,-2.572956186,-3.165287773,1.990801515,0.931855393,-15.12077276,-12.88565914,-18.11985852,-11.88559626,-17.58413857,-15.12861132,-8.204962869,-3.721585134 -2931,T178I,0.000736406,-0.041134244,-0.0304044,-1.170835854,-2.042598116,-0.058753062,0.063443801,-0.061970989,-0.067649964,-0.211809714,0.129541226,-0.065140492,0.004331693,-0.853665511,-1.488006197,-1.891836412,-2.19335982,2.277636322,1.644127827,-10.41823583,-9.8630392,-11.86712547,-7.999804581,-13.63960155,-8.721608345,-6.649185841,-3.40908366 -2932,T178H,0.000520577,0.024717927,-1.111527005,-1.926525519,-2.450143199,-0.055416713,0.040809223,-0.039768069,-0.012970483,0.026397423,0.02303843,-1.006565208,-1.216488802,-1.960146187,-1.892904851,-2.767868167,-2.13241823,2.383297662,1.049441673,-13.65985964,-10.27864773,-16.0813147,-10.12547282,-15.91915819,-15.89470478,-8.224240842,-4.217772212 -2933,T178K,0.032266966,0.010882636,-1.082954741,-1.99529304,-2.986548055,-0.083049002,0.056949239,0.007584692,-0.039758251,-0.056148862,0.077914134,-0.905966026,-1.259943455,-1.633150628,-2.357435452,-2.741902604,-3.231193505,2.365292051,1.154256435,-11.19116639,-10.86616194,-11.93956719,-9.855000443,-12.25556516,-11.03953719,-8.319398361,-2.996720873 -2934,T178M,-0.159316091,-0.061484069,-0.16277402,-2.053647471,-2.831918119,-0.013901697,-0.151496616,-0.167135566,-0.006810174,-0.095094832,-0.027873306,-0.19300239,-0.13254565,-1.4177713,-2.689523641,-2.22549328,-3.438342958,2.44000034,1.502885788,-12.05448831,-10.92130016,-13.46398085,-10.87705202,-14.12015848,-10.88995006,-8.851335481,-4.057826899 -2935,T178L,-0.005406741,0.023695416,-0.847496625,-2.061029743,-2.776831022,-0.041987435,0.030624998,-0.04143848,0.027525247,-0.054830529,0.10222136,-0.510537343,-1.184455906,-1.719614172,-2.402445313,-2.754579933,-2.799082111,1.789926526,0.862800013,-10.55280929,-9.718879784,-12.41741207,-9.020177841,-12.91728638,-8.690290352,-6.726409268,-2.972375323 -2936,T178N,-0.075980108,-0.091732399,-0.250229729,-1.488410418,-2.261183374,-0.084548093,-0.074040269,-0.077919947,0.118128562,-0.141389673,-0.042075125,-0.279419783,-0.221039675,-1.524887379,-1.451933456,-2.383761881,-2.138604866,1.527550817,0.836838192,-10.75136899,-10.41841404,-10.40395026,-9.562482758,-12.6922366,-10.67976128,-8.714224378,-5.445278977 -2937,T178Q,0.006552982,0.021178347,-0.057128605,-1.683283735,-2.094211605,-0.089752992,0.008790377,0.004315587,0.006039712,0.01672176,0.025634934,-0.092672314,-0.021584896,-1.493964918,-1.872602551,-2.067603692,-2.120819517,0.848268851,0.715892123,-11.47798253,-10.22602359,-11.54844435,-9.838138466,-12.69812693,-13.07917931,-7.630618371,-2.765967487 -2938,T178P,-0.00169372,-1.441202914,-2.189291616,-2.06671496,-2.863903087,-0.071357736,0.001721331,-0.005108771,-0.028500872,-1.504282424,-1.378123403,-2.264243782,-2.114339449,-1.953006939,-2.180422981,-2.821426759,-2.906379415,-0.139205876,-0.956815536,-12.91759115,-12.02074955,-14.03083274,-11.45113136,-14.31534618,-12.76989589,-10.05107184,-6.781916575 -2939,T178S,-0.003441828,0.006844634,-0.035690469,0.013058796,-0.131550732,-0.015353438,-0.011624939,0.004741283,0.039652913,-0.038237607,0.051926874,-0.083948522,0.012567585,0.008561019,0.017556572,-0.138716851,-0.124384613,1.385479405,2.213557418,-4.325837103,-3.573637657,-4.60095491,-3.907700607,-5.778857071,-3.768035271,-5.428455129,-1.902283268 -2940,T178R,-0.025958626,0.010140992,-1.297399273,-2.159343487,-3.014521567,-0.039309601,-0.005521028,-0.046396223,0.026489515,-0.026880178,0.047162161,-1.023374368,-1.571424178,-2.052790334,-2.26589664,-2.537205923,-3.491837211,2.14159828,0.839493752,-11.59679735,-8.757783035,-12.55387045,-10.01925752,-13.36581464,-13.28726111,-6.627665226,-2.447107713 -2941,T178W,-0.03968747,-0.811409977,-1.958377347,-2.182161219,-3.213571609,-0.087171004,-0.02886437,-0.05051057,0.036422341,-0.660259155,-0.962560799,-1.947508378,-1.969246316,-1.956606685,-2.407715752,-2.601601367,-3.82554185,1.604975157,-0.025735342,-14.01355529,-10.822115,-17.47463041,-11.83934553,-14.66753101,-15.26415453,-8.273587703,-2.075366433 -2942,T178V,-0.035448279,-0.007799816,-0.02147337,-0.732749027,-2.349552164,-0.0632658,-0.023071717,-0.04782484,0.0113224,-0.04280928,0.027209649,-0.082907378,0.039960638,-0.339526895,-1.125971159,-2.116176342,-2.582927986,1.463533972,1.331094486,-8.949479036,-9.008019516,-9.306102806,-7.444343788,-11.92293259,-7.065996475,-6.847592357,-2.52747589 -2943,T178Y,-0.032703631,0.029025183,-1.155732099,-2.469291866,-2.946532519,-0.019010945,0.012512685,-0.077919947,0.11011059,0.0188679,0.039182466,-0.656960112,-1.654504085,-1.96272361,-2.975860122,-2.645506853,-3.247558184,1.795647575,0.77819285,-15.35096205,-11.55716823,-19.14184499,-11.18590287,-17.06402663,-17.80586755,-7.823560892,-2.118714087 -2944,T179A,0.046224395,-0.034006388,-0.184595751,-1.513048887,-1.6994956,-0.097910391,0.013945239,0.07850355,0.009869948,-0.141551417,0.073538642,-0.341185054,-0.028006447,-1.54341548,-1.482682293,-1.756056227,-1.642934972,3.726344202,2.714467013,-5.843847989,-8.64626722,-5.965363625,-4.910584366,-4.901592003,-4.795432732,-6.170942619,-1.78980376 -2945,T179C,-0.049214393,-0.073504932,0.035947226,-0.590763737,-2.572330785,-0.031309429,-0.030145346,-0.06828344,0.041238061,-0.259473637,0.112463773,-0.16937926,0.241273711,-0.480311223,-0.70121625,-2.508529719,-2.636131851,1.41598106,1.171384054,-9.565857422,-9.471306709,-11.46705871,-8.732470367,-10.22974149,-7.928709831,-6.901180173,-4.175655389 -2946,T179E,0.012978503,-1.875414462,-2.481677151,-1.923231694,-3.131540263,-0.072050143,0.040023084,-0.014066079,-0.072041998,-2.04604899,-1.704779934,-2.847947041,-2.115407261,-2.062766594,-1.783696793,-2.956648579,-3.306431946,-0.359593094,-1.157479169,-12.78221337,-13.73978926,-13.70065312,-12.21706234,-12.14180316,-12.11175899,-10.68517917,-10.18987442 -2947,T179D,0.09151922,-1.548125944,-2.477151476,-2.575338244,-2.704465567,-0.133196924,0.098789712,0.084248727,-0.063712592,-1.76322738,-1.333024508,-2.468215418,-2.486087534,-2.586124958,-2.56455153,-2.576916956,-2.832014178,-0.330365872,-1.096292652,-11.93087944,-12.24223439,-13.13375864,-11.28712727,-11.75428349,-11.2369934,-9.504102092,-7.616943493 -2948,T179G,0.049456347,-0.521488732,-1.661472168,-2.159479019,-2.870286433,-0.086859955,0.030095731,0.068816963,0.029438108,-0.436986072,-0.605991392,-1.92799038,-1.394953956,-2.221991178,-2.096966859,-2.792566773,-2.948006093,1.35074276,-0.048739024,-10.47686178,-12.81975514,-10.51406255,-8.826246361,-10.27706812,-9.947176743,-7.421709612,-2.512771379 -2949,T179F,-0.057359255,-1.241090351,-2.102766596,-1.899923368,-2.330080687,-0.029462931,-0.086180462,-0.028538048,-0.132739838,-1.538492942,-0.94368776,-1.942450985,-2.263082207,-1.458300533,-2.341546203,-2.051152522,-2.609008851,4.447149512,2.146055538,-13.66231712,-14.83172106,-14.70609365,-13.40496555,-15.36751414,-10.00129122,-8.241111028,-5.475248998 -2950,T179I,0.111410498,-0.028284634,-1.745160612,-1.780878011,-1.472474702,0.114060975,0.144961393,0.077859603,-0.103968096,-0.081575074,0.025005807,-1.455569893,-2.03475133,-2.050600687,-1.511155335,-1.56427143,-1.380677974,4.204330134,2.643211072,-9.269183092,-10.01742411,-10.88942033,-8.53746151,-11.49598026,-5.40562925,-6.627699427,-2.909197178 -2951,T179H,0.012877772,-1.303707478,-1.676213252,-2.376460011,-2.505587335,0.059222059,0.008978361,0.016777182,-0.116578179,-1.788370416,-0.819044539,-2.192328458,-1.160098046,-2.310237997,-2.442682025,-2.301029996,-2.710144673,0.141101471,-1.075798029,-13.95466253,-14.28363422,-14.51824043,-12.9535786,-14.23689232,-13.78096706,-10.67763656,-10.15915838 -2952,T179K,-0.011041428,-1.822209013,-2.100719546,-1.82872497,-2.108367291,0.048145843,0.031302258,-0.053385113,-0.142445147,-2.258192432,-1.386225594,-2.361120478,-1.840318614,-2.178000022,-1.479449917,-2.469822016,-1.746912565,-0.346455695,-1.195983602,-13.45336046,-13.61319967,-14.91137661,-12.61603802,-13.06823528,-13.05795271,-10.68517917,-10.18987442 -2953,T179M,0.051896884,-0.348828327,-1.243939065,-1.644658584,-1.436712697,-0.149468479,0.02027316,0.083520607,-0.052177686,-0.392206665,-0.305449989,-1.581494542,-0.906383587,-2.09734409,-1.191973077,-1.69019608,-1.183229313,4.55421996,2.840883531,-11.92121004,-13.05763191,-13.21479869,-11.66723624,-12.90897221,-8.757411133,-7.632178918,-4.671417629 -2954,T179L,0.0467481,-0.659976033,-1.89705447,-1.961767843,-2.752004814,-0.08142222,0.019748398,0.073747802,0.013447169,-0.602659211,-0.717292855,-2.391328996,-1.402779943,-2.333147277,-1.590388409,-2.323939275,-3.180070352,0.356887531,-0.526893457,-13.51458116,-14.19646787,-15.41489374,-13.4997104,-15.50864189,-8.953191879,-8.188619927,-5.50696152 -2955,T179N,0.134326907,-1.630328298,-2.092827224,-2.191013992,-2.320141315,-0.063187442,0.105464825,0.163188989,0.000382347,-1.978702114,-1.281954481,-2.08163016,-2.104024287,-2.1995397,-2.182488284,-2.190331698,-2.449950932,-0.48914258,-1.109061411,-10.20093108,-10.10105673,-10.35465483,-10.17658924,-10.52864664,-9.843707977,-8.673711929,-6.884448013 -2956,T179Q,-0.015754079,-1.576327813,-1.990371733,-2.438043503,-2.717685824,-0.079204905,-0.019437492,-0.012070666,-0.07939943,-2.031408464,-1.121247161,-2.134336511,-1.846406954,-2.25224605,-2.623840955,-2.544068044,-2.891303603,-0.657770297,-1.14687837,-13.65205633,-14.67012868,-14.11962594,-13.06034309,-13.52339722,-12.88678672,-10.68517917,-10.18987442 -2957,T179P,0.048037519,-1.255365937,-1.751160922,-1.627013075,-1.894521109,-0.050044702,0.016876849,0.079198188,-0.110979975,-1.814699354,-0.696032519,-2.695778651,-0.806543193,-2.336566936,-0.917459214,-2.804480189,-0.984562028,-0.337213478,-1.133917636,-13.30512378,-14.61875855,-13.72397119,-12.90649961,-13.06696815,-12.20942139,-10.52067966,-9.329510657 -2958,T179S,0.050563725,-0.033441299,-0.016904334,-0.013030819,-0.230557033,-0.106557807,0.010161224,0.090966225,0.018490432,-0.167483567,0.10060097,-0.198975952,0.165167284,-0.217526234,0.191464596,-0.278533761,-0.182580305,1.520701975,2.015642167,-3.07001349,-4.10689785,-3.909756836,-2.394115967,-2.675653084,-2.263643715,-3.048891732,-1.006407282 -2959,T179R,0.032514294,-1.533280333,-2.152483282,-2.102102574,-2.425682559,-0.047581306,0.029446135,0.035582453,-0.066826989,-1.790536477,-1.276024189,-2.291404533,-2.013562031,-2.35816155,-1.846043598,-2.40010607,-2.451259048,-0.387092355,-1.104469924,-14.1855317,-15.46951534,-13.9636358,-13.91841853,-13.70309732,-13.87299149,-10.68517917,-10.18987442 -2960,T179W,-0.160617163,-1.630715744,-2.390331997,-2.639033763,-2.981145452,0.068954846,-0.094602604,-0.226631721,-0.045164769,-1.710765558,-1.550665929,-2.85508629,-1.925577704,-2.671965833,-2.606101692,-2.963787827,-2.998503077,-0.235915717,-1.079268797,-14.43779244,-14.70340348,-15.49979241,-14.19424425,-15.32971284,-12.46180922,-9.213889826,-6.969712011 -2961,T179V,0.012128883,-0.058741129,-0.387666413,-2.003287679,-2.521490628,-0.029620795,0.008738108,0.015519658,-0.032369293,-0.18819049,0.070708232,-0.418261019,-0.357071807,-1.896637742,-2.109937616,-2.364550995,-2.67843026,1.629438593,0.766679228,-8.930573801,-10.85512756,-10.00932064,-8.199188515,-10.54125449,-5.047977798,-7.511814428,-3.134082269 -2962,T179Y,0.077284132,-1.522037125,-2.135051049,-1.693647194,-2.36236514,-0.316603661,0.141928553,0.012639711,-0.152335394,-1.704824364,-1.339249885,-2.108782406,-2.161319691,-1.624631955,-1.762662433,-2.217483944,-2.507246335,-0.105173396,-1.096946164,-15.91530202,-16.65486102,-17.0069881,-15.08405989,-16.8198632,-14.01073789,-10.68517917,-10.18987442 -2963,M180A,0.008215116,-0.106658841,-0.058799686,-0.018438764,-0.127120803,-0.03369834,-0.069038768,0.085468999,-0.025102365,-0.109792358,-0.103525323,-0.083305809,-0.034293563,-0.060150238,0.023272711,-0.101332826,-0.152908779,1.522361272,2.396863212,1.091029861,0.839207947,0.965141968,0.656144539,2.549608978,0.445045876,-3.253398392,1.879469323 -2964,M180C,-0.173642439,-0.074819542,-0.038632127,-0.044083199,-0.117845373,-0.105596893,-0.24841296,-0.098871917,-0.037071311,-0.070126153,-0.079512931,-0.00975172,-0.067512533,-0.049865243,-0.038301154,0.012459399,-0.248150144,1.176585771,2.544189688,-3.036060364,-3.825002327,-2.274353386,-4.606796455,-1.978913582,-2.495236069,-4.212939077,1.755521637 -2965,M180E,0.060155236,-0.06130517,0.029652502,-0.005679826,-0.043949874,-0.0241386,-0.014978671,0.135289142,-0.038337846,-0.064833865,-0.057776474,0.047726628,0.011578375,-0.026477461,0.01511781,-0.063644971,-0.024254776,1.177169581,2.264657126,-2.833061012,-3.273310051,-1.95759153,-3.94892128,-2.875169098,-2.110313103,-4.812177481,0.502236753 -2966,M180D,-0.177434819,-0.033802104,0.027280211,0.003269307,-0.39934093,-0.122231075,-0.255733056,-0.099136581,0.004468816,0.011311442,-0.078915649,0.054384287,0.000176135,-0.022982051,0.029520664,-0.189061742,-0.609620117,1.472080924,2.185546032,-3.168685245,-4.345851471,-3.081370827,-4.416568024,-2.95901931,-1.040616592,-4.248461785,0.481216293 -2967,M180G,0.02159364,-0.09698127,0.012540552,0.006400223,-0.192624745,-0.067349739,-0.144202078,0.187389358,-0.010244842,-0.067990057,-0.125972483,0.054606192,-0.029525089,0.006745484,0.006054962,-0.098737868,-0.286511622,1.37136561,2.355056469,-2.634155504,-2.825204819,-1.850834656,-3.848986977,-1.144645424,-3.501105644,-5.563584284,-1.163148938 -2968,M180F,-0.137961776,-0.073684493,-0.003725579,-0.002144089,-0.296461378,-0.062312282,-0.243645068,-0.032278484,-0.072206633,-0.040356768,-0.107012218,0.092724748,-0.100175905,-0.050662845,0.046374667,-0.212769092,-0.380153664,1.339979813,2.030862812,-5.143784602,-5.451436256,-4.207999901,-7.755996933,-3.907310341,-4.396179581,-7.092650281,-4.335715261 -2969,M180I,-0.175232049,-0.096711958,0.023511436,-0.016955155,-0.224523194,-0.090462333,-0.282816057,-0.06764804,-0.082307511,-0.107303558,-0.086120357,0.098214202,-0.05119133,0.001434823,-0.035345133,-0.122807939,-0.326238448,1.169010989,2.087660019,-2.2720438,-2.501510033,-2.138886848,-2.278295647,-2.350624977,-2.090901497,-5.855717451,-1.430334393 -2970,M180H,0.28945582,-0.089866698,0.031378431,0.02238592,-0.061344188,-0.019527701,-0.090929009,0.669840648,0.080077623,-0.004308869,-0.175424526,0.052520283,0.010236578,0.044229716,0.000542124,-0.015279688,-0.107408688,1.256750483,2.6500553,-3.888426958,-5.178946655,-2.947540154,-6.341737953,-2.375853256,-2.59805677,-5.01282071,0.061475633 -2971,M180K,0.039312705,-0.116649048,-0.041719726,-0.035898887,-0.125447739,0.02902923,-0.107908112,0.186533522,-0.039019485,-0.110229824,-0.123068272,0.063957169,-0.14739662,-0.056104498,-0.015693276,-0.094217154,-0.156678323,1.344368611,2.303353519,-1.753161853,-2.333038963,-0.640192879,-3.249430511,-0.921341789,-1.621805122,-4.352930502,1.252429639 -2972,M180L,0.173486957,-0.043903289,0.013349803,0.008802413,-0.369663227,-0.013837764,-0.058916825,0.405890739,-0.010640204,-0.04958979,-0.038216788,0.016918341,0.009781264,-0.022956186,0.040561012,-0.297907832,-0.441418622,1.646510368,2.155408192,-1.763088551,-2.211988342,-1.565842712,-1.395887825,-2.436505859,-1.205218018,-4.894440691,-0.58010352 -2973,M180N,-0.152342886,-0.013869412,0.089519141,0.045360487,-0.097824551,-0.025053282,-0.235036058,-0.069649713,0.037788561,-0.010660885,-0.017077939,0.166611058,0.012427224,0.036308645,0.054412329,0.041264341,-0.236913442,1.543610422,3.106887046,-1.740152194,-2.544612305,-0.807760422,-3.898207787,-1.863386719,0.413206261,-3.605959879,1.395519366 -2974,M180Q,0.824528157,-0.109708877,0.061642395,0.084655964,0.012836888,-0.048919811,0.174265148,1.474791165,0.026832804,-0.061980579,-0.157437174,0.041120486,0.082164303,-0.02497842,0.194290348,0.024319624,0.001354152,1.169118559,2.719743615,-1.858476291,-2.652852974,-0.990546577,-2.641682213,-1.917312157,-1.089987534,-4.367765494,0.605369007 -2975,M180P,0.270050771,-0.073583678,-0.073800273,-0.7678384,-1.07766428,-0.088081661,-0.075534014,0.615635555,-0.01053098,-0.063618023,-0.083549333,-0.105932339,-0.041668206,-1.499512912,-0.036163888,-2.064638692,-0.090689868,2.627244526,1.67407162,-1.95131579,-1.337159477,-1.771884178,-3.429864822,-1.115733612,-2.101936859,-4.499697613,0.40678485 -2976,M180S,-0.012612296,-0.039474102,0.041602301,0.069145843,-0.033144855,-0.056211766,-0.069622843,0.044398252,-0.010363337,-0.023323429,-0.055624775,0.037735647,0.045468955,0.038173095,0.100118591,0.055823061,-0.12211277,1.157092833,2.724819397,3.373192923,4.326895508,3.789994797,1.311933609,4.098695068,3.338445633,-1.593434617,4.733808609 -2977,M180R,0.205962724,-0.101795828,-0.024229855,-0.003690476,-0.145705402,-0.004266155,-0.058513869,0.470439317,0.012575999,-0.063020753,-0.140570903,0.006324581,-0.05478429,-0.003608307,-0.003772645,-0.119417768,-0.171993036,1.255915528,2.152573235,-2.215126413,-3.676825005,-0.934614449,-3.457358025,-1.098720741,-1.908113846,-3.948917893,1.811703761 -2978,M180T,0.054493254,-0.06500485,-0.001645969,-0.024702962,0.02379943,-0.027053503,-0.089290132,0.19827664,0.040511419,-0.066780129,-0.06322957,0.004767404,-0.008059342,-0.069831409,0.020425486,0.037038955,0.010559905,1.666915459,3.610469941,6.01622346,7.249510506,5.492690681,5.487993538,6.1231147,5.727807877,0.436438818,5.898483477 -2979,M180W,0.015625657,-0.108573852,-0.032831947,-0.008438496,-0.152728798,0.018246246,-0.047578088,0.078829401,-0.053435027,-0.080270873,-0.136876831,0.04164925,-0.107313143,-0.024687286,0.007810295,-0.157597953,-0.147859643,1.326295974,2.132192502,-5.2740229,-5.866425446,-4.635393738,-7.039743561,-4.021189957,-4.807361801,-7.092650281,-4.335714809 -2980,M180V,-0.035934004,-0.073453965,-0.000560854,0.01201426,-0.080730722,-0.012497858,-0.134887684,0.063019677,0.005543353,-0.048671887,-0.098236042,0.024519924,-0.025641631,-0.023729635,0.047758155,-0.023238143,-0.138223301,1.412703685,2.657661517,-0.339507751,-1.094431198,-0.026790733,0.209104256,-0.19065786,-0.594763222,-4.064971312,0.503577901 -2981,M180Y,-0.053329242,-0.113604064,0.004655077,-0.066346548,-0.195293479,0.009574324,-0.115565927,0.008907444,0.02650755,-0.157362281,-0.069845846,0.047225843,-0.03791569,-0.098771558,-0.033921538,-0.10713551,-0.283451447,1.470960317,2.357611993,-5.067096524,-5.700612961,-4.521300133,-8.284508286,-2.576757568,-4.252303673,-5.857609942,-0.874274455 -2982,P181A,-0.022723504,0.032185041,0.033034793,0.036470937,-1.419223265,0.040446662,0.028343059,-0.073790067,-0.022621113,0.005747189,0.058622892,0.049784104,0.016285482,0.054753096,0.018188778,-1.2050704,-1.633376129,0.702941862,1.338779173,-5.513981544,-4.651524384,-7.087552383,-5.899771355,-5.55784758,-4.373212021,-4.75221122,-1.098045272 -2983,P181C,0.016975172,-0.044518649,0.017524572,-0.036252022,-1.356029739,0.084111875,-0.108180326,0.14213067,-0.060206304,-0.03174083,-0.057296467,0.047859847,-0.012810704,0.020191933,-0.092695976,-0.880487403,-1.831572075,0.708401941,1.37035961,-11.58361113,-10.5397231,-13.96978693,-11.49255343,-11.05771031,-10.85828185,-8.354583134,-5.905761929 -2984,P181E,-0.050069249,-1.526431003,-2.304448559,-2.150489505,-2.374074613,0.03711098,0.023577383,-0.123715881,-0.082608655,-1.510688133,-1.542173873,-2.592001413,-2.016895704,-1.818188382,-2.482790628,-2.397223266,-2.35092596,0.160193341,-0.9721001,-13.24538967,-12.36802357,-15.56660244,-12.78681053,-12.95973222,-12.5457796,-10.54740915,-10.48901789 -2985,P181D,0.032789424,-1.589495511,-1.952682532,-2.852328464,-3.181340254,0.031623061,0.080901601,-0.015322754,-0.101493999,-1.639087401,-1.53990362,-2.039159444,-1.866205619,-2.770496392,-2.934160535,-2.923562544,-3.439117964,-0.11719307,-1.049545466,-13.43531346,-13.13638719,-15.67102435,-12.8530085,-12.5812394,-12.93490783,-10.54740915,-10.48901789 -2986,P181G,-0.015779644,-0.033697753,-0.002778673,-1.481830678,-2.424367976,0.062659844,0.0205844,-0.052143687,-0.031522942,-0.062664225,-0.00473128,-0.010419345,0.004861999,-1.234158767,-1.729502588,-2.323882254,-2.524853698,1.007311317,0.763290707,-11.29686079,-10.63734967,-13.01452847,-11.50004712,-10.96436321,-10.36801546,-8.584840925,-6.048170402 -2987,P181F,-0.150897543,-1.497621318,-2.122247712,-2.283333016,-3.177511691,0.134045505,0.020250001,-0.322045086,-0.132278553,-1.534098892,-1.461143744,-1.837260922,-2.407234502,-2.267567873,-2.299098158,-2.89775528,-3.457268101,0.113428037,-1.010749196,-14.6119937,-13.51258096,-17.35671539,-14.41161508,-13.81931097,-13.95974609,-10.54740915,-10.48901789 -2988,P181I,-0.134727095,-0.009458025,0.045668168,-1.310542795,-2.435086889,0.100693126,0.001255364,-0.270709554,-0.134707239,-0.060257251,0.041341202,0.075123068,0.016213267,-0.760302477,-1.860783112,-1.867611139,-3.002562639,1.746575183,1.413475877,-13.21137184,-11.79870509,-15.04863365,-12.29879764,-12.78133774,-14.12938509,-9.039852408,-7.164707093 -2989,P181H,-0.048541475,-1.103612453,-1.945827214,-2.342053433,-3.034564588,0.06499383,0.003874465,-0.100957415,0.02430223,-1.075014778,-1.132210128,-1.875501449,-2.016152978,-2.247816454,-2.436290412,-2.525821342,-3.543307833,0.263285832,-0.67436389,-13.60648739,-12.81653651,-15.85143327,-13.19150572,-12.92064789,-13.25231357,-10.54740915,-10.48901789 -2990,P181K,-0.025928549,-1.466039987,-2.003690444,-2.04595424,-3.084530684,0.027155428,0.027781854,-0.079638951,-0.108191023,-1.645119366,-1.286960607,-1.734401576,-2.272979312,-2.118951037,-1.972957442,-2.669957198,-3.49910417,0.060252915,-0.933365305,-13.49401973,-12.43319302,-16.1959659,-12.8293828,-12.81952224,-13.19203471,-10.54740915,-10.48901789 -2991,P181M,-0.098847394,-0.028208582,-0.841563171,-1.790765766,-2.428427535,0.089206098,0.056031599,-0.253726387,-0.117038586,-0.065682235,0.009265071,-0.672307289,-1.010819052,-1.847884265,-1.733647266,-2.603010408,-2.253844661,2.091813613,0.952711018,-11.44955091,-10.40187309,-13.48620638,-11.34645129,-10.89099654,-11.12222723,-8.185210046,-5.818316875 -2992,P181L,-0.131670244,-0.038127028,-0.183004558,-1.598331948,-2.624131341,0.10703717,0.01461772,-0.277958208,-0.066362607,-0.055855188,-0.020398868,-0.118436176,-0.24757294,-1.458884545,-1.737779351,-2.332110001,-2.91615268,1.039236286,0.7402016,-10.73324673,-9.224401497,-13.28901377,-10.02836897,-10.05376411,-11.0706853,-7.053453554,-3.353202947 -2993,P181N,-0.062651752,-0.735730008,-2.000459697,-2.191598684,-2.972155468,0.065117217,-0.003002056,-0.122301447,-0.020058454,-0.638146727,-0.833313289,-2.226866065,-1.774053328,-2.055113026,-2.328084341,-2.907149183,-3.037161752,0.624403086,-0.491344023,-11.10932125,-10.92237074,-12.75502087,-10.25473325,-10.332674,-11.28180738,-8.370642265,-5.224077195 -2994,P181Q,-0.091120447,-1.610218476,-2.10104175,-2.002870084,-2.940623847,-0.018370495,-0.058151283,-0.12408961,-0.108695621,-1.656497887,-1.563939065,-1.709782444,-2.492301056,-1.787906877,-2.217833291,-2.895215539,-2.986032155,4.022647929,1.673105928,-11.83239411,-11.01797291,-14.29214009,-11.23801759,-11.1792264,-11.43461356,-9.020694037,-7.164707096 -2995,P181S,-0.038313146,-0.0383175,0.007653302,-1.260847925,-2.254049517,0.053807527,-0.002173023,-0.074453269,-0.046064724,-0.064134906,-0.012500094,-0.016631794,0.031938397,-0.817529147,-1.704166702,-2.122883644,-2.38521539,1.956446007,1.404494832,-8.61924234,-8.131993233,-10.19503205,-9.101835182,-8.502683632,-7.164667603,-6.603327967,-3.815972448 -2996,P181R,0.004046027,-1.735702055,-2.048371797,-2.299015958,-3.55518077,0.065697275,0.012324236,-0.004232183,-0.118663829,-1.895500536,-1.575903574,-2.057333413,-2.039410181,-2.099460193,-2.498571722,-3.293919031,-3.816442508,0.000694101,-1.109635779,-13.11717433,-12.41906194,-14.81943009,-12.80895535,-12.73073528,-12.80768898,-10.54740915,-10.48901789 -2997,P181T,-0.031600892,0.012677177,0.017219461,-0.455022181,-2.108980881,0.054766632,0.028988526,-0.09219031,-0.050446467,0.004298352,0.021056001,-0.006827567,0.041266488,-0.238671216,-0.671373146,-2.016807603,-2.201154158,1.278034174,1.324510739,-7.811983484,-6.262653259,-8.733705688,-8.3772715,-8.188736382,-7.497550591,-6.145297457,-4.13882665 -2998,P181W,0.040879226,-1.559352892,-1.896963652,-2.583625217,-2.912637008,0.14106328,0.01135693,0.070401522,-0.166681616,-1.723899293,-1.394806491,-2.027061323,-1.76686598,-2.457368274,-2.709882159,-2.610434427,-3.214839589,-0.137028183,-1.129968582,-14.14468692,-13.32915636,-16.88926505,-13.66471542,-13.30778165,-13.53251613,-10.54740915,-10.48901789 -2999,P181V,-0.090079763,0.006426027,-0.018369568,0.009570495,-1.122286199,0.065959908,0.026661527,-0.206821053,-0.030463631,-0.048083497,0.060935551,-0.019064086,-0.01767505,0.027486448,-0.008345458,-0.831464525,-1.413107873,0.615624468,1.361173144,-10.01241568,-9.202768173,-11.43838967,-9.349241455,-10.35580881,-9.71587027,-7.680713474,-3.762666171 -3000,P181Y,-0.001316157,-1.622208455,-2.322468686,-2.13956668,-3.051126408,0.033762493,0.068853851,-0.071486165,-0.121123472,-1.56852284,-1.675894069,-1.898013809,-2.746923563,-1.976138243,-2.302995117,-2.481386913,-3.620865903,0.242438345,-0.979933231,-14.57635852,-13.43875423,-17.40130486,-14.29965802,-13.72607599,-14.01599953,-10.54740915,-10.48901789 -3001,A182C,0.025894036,-0.035709563,0.03173834,-0.007392236,-0.004182229,0.005275856,0.032091526,0.019696545,0.012138082,-0.076976242,0.005557116,0.02795338,0.0355233,-0.035918838,0.021134366,-0.019605707,0.011241249,1.276755325,2.520657352,-6.119038477,-5.739468948,-6.375403572,-6.63780127,-5.360942719,-6.481575874,-5.076847329,-4.590254722 -3002,A182E,-0.00959176,0.002769044,-0.018941232,-0.032108016,-0.009028852,0.024502578,-0.021744948,0.002561429,0.026587702,-0.04068047,0.046218557,-0.01852068,-0.019361784,-0.041988405,-0.022227627,-0.050964512,0.032906808,1.237588698,2.353131451,-0.049515779,0.344674858,-0.79551416,-0.705582497,0.549976257,0.358866646,-0.908612808,-0.920502242 -3003,A182D,-0.010321046,0.004460448,-0.038380233,-0.039691878,-0.42100508,-0.039974477,-0.018024089,-0.002618003,-0.007955333,-0.024458627,0.033379523,-0.02865837,-0.048102096,-0.030701684,-0.048682072,-0.349713804,-0.492296355,1.261472171,1.80289256,-1.326406583,-1.882308281,-0.986169266,-1.357856781,-1.726025696,-0.67967289,-2.252444481,-1.445026718 -3004,A182G,0.02474292,0.03109095,0.02683687,0.009605273,0.037299283,0.00696928,0.020250527,0.029235312,0.011781208,0.018232331,0.043949569,0.026464506,0.027209234,0.018020793,0.001189752,0.031112921,0.043485644,1.086110299,2.62480595,-3.78876118,-3.685652123,-2.965182999,-3.736308296,-3.568226028,-4.988436455,-4.513010149,-2.079500819 -3005,A182F,-0.004257486,-0.002313163,0.006694042,0.01810184,0.01557299,0.028361985,0.011636674,-0.020151646,0.012579858,0.04583455,-0.050460876,0.047137961,-0.033749877,0.033048262,0.003155417,0.083454082,-0.052308102,1.187700577,2.906081422,-5.899384666,-5.951768166,-6.107528893,-6.410334473,-4.485142113,-6.542149689,-4.748530465,-3.341097594 -3006,A182I,0.028114988,-0.031001179,0.00765558,-0.007619298,-0.029102077,0.051181332,0.021266758,0.034963217,-0.074029565,-0.053269597,-0.008732761,-0.018920706,0.034231865,-0.046202227,0.030963631,-0.015450191,-0.042753963,1.221686564,2.513350546,-3.07031972,-2.683047493,-3.808281799,-3.440279915,-1.897979225,-3.52201017,-2.445307402,-2.434743257 -3007,A182H,0.006833372,0.024640913,0.035440031,0.007522533,0.046813931,0.003555846,-0.01156469,0.025231434,-0.002397972,0.023484947,0.025796878,0.034870672,0.036009389,0.002165945,0.01287912,0.030381787,0.063246075,1.095078236,2.628622803,-3.917588417,-3.30811161,-4.085450417,-4.71502243,-3.434905853,-4.044451775,-3.133706316,-2.454418826 -3008,A182K,0.106650208,0.017039981,0.069344958,0.058207835,0.071641012,0.021031327,0.077300884,0.135999532,0.019909909,-0.068398619,0.102478581,0.055242747,0.083447169,0.02064001,0.095775659,0.035489328,0.107792696,1.272180895,2.764454626,-1.768100172,-1.420956551,-2.213060387,-2.658405342,-0.683435997,-1.864642586,-2.532186713,-0.679861378 -3009,A182M,0.063272862,-0.018380102,-0.025762653,-0.011764165,0.02676237,0.104492139,0.116584602,0.009961121,0.051071299,-0.057193315,0.020433112,-0.061362464,0.009837159,-0.015926133,-0.007602196,-0.022789666,0.076314406,1.281820378,2.54075862,-4.570704352,-4.386302979,-4.846672096,-4.97599807,-3.894245148,-4.750303467,-4.018196716,-3.28021597 -3010,A182L,-0.000940848,-0.007574905,0.052682988,0.019510469,0.023923761,-0.028036943,0.02475238,-0.026634075,0.007588534,0.015478001,-0.030627811,0.046461632,0.058904343,0.034004837,0.005016101,0.04102483,0.006822692,1.253677904,2.843603555,-2.790549126,-2.512883537,-3.042941605,-2.268565147,-2.126583397,-4.001771942,-2.755636434,-1.088699649 -3011,A182N,0.055181494,0.029055925,0.013848575,-0.011045558,-0.025473966,0.019931853,0.069258093,0.041104894,-0.015353459,-0.02333283,0.081444679,-0.048063787,0.075760937,-0.041857985,0.019766869,-0.036723036,-0.014224895,1.346056256,2.522759118,-1.306266574,-0.925605583,-1.2738601,-2.106773369,-0.621586578,-1.60350724,-2.398780227,-1.444579874 -3012,A182Q,0.002359254,0.084452701,0.03631002,0.035223233,0.008577633,0.038149821,0.010126007,-0.0054075,0.034397991,0.063174851,0.10573055,0.056592204,0.016027836,0.026528926,0.04391754,0.021308992,-0.004153727,1.215430296,2.853343768,-1.820945757,-1.474361191,-2.05743457,-2.280425407,-1.041883675,-2.25062394,-2.721374344,-1.696564811 -3013,A182P,0.001457656,-0.02581082,0.002850225,-0.015261643,-1.656836061,-0.029733933,0.014654502,-0.011739191,-0.000585316,-0.023340593,-0.028281047,-0.022894423,0.028594872,-0.031207267,0.000683981,-1.541237199,-1.772434923,0.769064473,1.323497125,-6.62325748,-6.56815416,-6.906690308,-7.071876045,-5.447978241,-7.121588646,-5.735882589,-4.541173962 -3014,A182S,-0.026177605,-0.03523688,0.008293303,-0.010591371,-0.006001543,-0.009138009,-0.032693259,-0.019661951,-0.019298919,-0.023383342,-0.047090417,0.010396806,0.006189799,0.018418045,-0.039600786,0.020346033,-0.032349118,1.133628043,2.778342412,-2.052990106,-2.421104118,-2.059808342,-2.394002342,-1.015357262,-2.374678467,-2.324410797,-1.419696797 -3015,A182R,0.025848383,0.00464593,0.021281539,-0.003368994,0.020417383,0.002075713,0.030925892,0.020770873,-0.010317935,-0.013232297,0.022524157,0.012336755,0.030226322,-0.010593766,0.003855778,-0.002532481,0.043367246,1.212823993,2.588918956,-1.606787746,-0.928863205,-1.811418785,-2.428082932,-1.085835442,-1.779738365,-1.516146613,0.519177056 -3016,A182T,0.012578783,-0.002244852,0.031140745,0.025650758,-0.023171976,0.009294604,0.014848667,0.010308898,0.002715652,0.008608254,-0.013097958,0.041812201,0.020469288,0.046609433,0.004692083,-0.012757814,-0.033586137,1.156526309,2.563583434,-2.522444884,-2.611330223,-2.743861244,-2.951888542,-1.670859657,-2.634284752,-3.041150976,-2.246883451 -3017,A182W,-0.01898659,-0.018896031,-0.000376701,-0.018677241,0.024065487,-0.008680062,0.037002792,-0.074975971,0.021440265,-0.09683879,0.059046728,-0.071970294,0.071216892,-0.112318617,0.074964135,-0.044631391,0.092762364,1.259706967,2.367387496,-6.386762497,-5.934479645,-6.44431575,-6.751424736,-5.699582748,-7.104009605,-5.296708265,-4.364194988 -3018,A182V,0.013361785,0.013922575,0.01616376,-0.02134548,0.022611642,0.008248703,0.0000716,0.02665197,0.011941461,-0.006353799,0.034198948,0.013599723,0.018727797,-0.015563672,-0.027127288,0.000869037,0.044354246,1.183886993,2.526818017,-2.094048015,-1.981086258,-2.758085876,-2.124738396,-1.560268433,-2.046061111,-0.982883199,-1.954396928 -3019,A182Y,0.003872978,-0.045122269,0.01585435,0.01144438,0.039926568,-0.011408199,-0.022898875,0.03064483,-0.011054841,-0.052772977,-0.037471561,0.01319002,0.018518679,-0.024094922,0.046983682,0.037652938,0.042200197,1.219011973,2.738503741,-4.789803189,-4.535424896,-5.09901075,-6.003264908,-3.178655808,-5.132659584,-4.547569096,-1.662790943 -3020,A183C,-0.023740565,-0.074572573,-0.034712441,0.028587076,-0.496674031,0.012805835,0.011003116,-0.058484245,0.065533554,-0.024268642,-0.124876504,-0.019668589,-0.049756292,0.019267825,0.037906326,-0.357078711,-0.636269351,1.260685515,1.809424226,-7.844315279,-7.741622307,-7.933077751,-8.926923927,-8.00489801,-6.615054398,-6.940710673,-6.808251863 -3021,A183E,-0.072080794,0.012492863,-0.024964232,0.010272526,-0.111302744,-0.005970805,-0.022313125,-0.121848463,-0.009832962,0.014263519,0.010722207,-0.050594075,0.000665611,-0.034310701,0.054855752,-0.122446519,-0.100158969,1.318359053,2.187937015,-5.878227106,-5.970086739,-5.952479385,-6.762154678,-5.870847382,-4.835567345,-4.593363869,-1.354005012 -3022,A183D,-0.050307149,-0.021346665,-0.044231979,-0.029827562,-1.46783653,-0.116659157,-0.017231761,-0.083382537,-0.017901732,-0.108264213,0.065570884,-0.07387401,-0.014589947,-0.076431073,0.01677595,-1.192238584,-1.743434475,1.160131034,1.415927472,-6.399778052,-6.758212006,-6.66582428,-8.458146935,-5.678406662,-4.438300377,-4.961661067,-0.638759628 -3023,A183G,-0.031872006,0.006684963,0.000783183,0.017655141,-1.016716013,0.01170527,-0.010363366,-0.053380646,-0.011716642,-0.000943303,0.014313229,0.016722535,-0.01515617,-0.003360873,0.038671154,-0.744340076,-1.28909195,0.742327626,1.396991794,-6.106286494,-5.870678284,-7.522611496,-5.873915527,-6.097609818,-5.166617348,-4.528649948,-2.596448566 -3024,A183F,-0.014698799,-0.000513327,0.002836386,0.040355472,-0.294205693,-0.012090097,0.012583759,-0.041981356,-0.003670362,0.021331706,-0.022358359,0.046922878,-0.041250107,0.052859971,0.027850973,-0.186838521,-0.401572865,1.426920808,2.208931766,-8.013651286,-8.201744965,-7.801592529,-9.079235298,-8.343025909,-6.64265773,-6.021257791,-5.881729214 -3025,A183I,-0.087892656,0.035942818,-0.013414604,-0.021887098,-0.133558866,0.025184544,-0.064135072,-0.11165024,0.016256034,0.028260409,0.043625227,-0.015988105,-0.010841102,-0.004967501,-0.038806694,-0.13286752,-0.134250211,1.406169601,2.276767748,-6.148597092,-4.978259064,-6.663653427,-6.891743996,-7.486657944,-4.722671028,-4.973782923,-5.450722995 -3026,A183H,-0.027769589,0.029980958,0.018963983,0.07515109,-0.054851679,0.056062135,0.056747148,-0.112286325,-0.018488336,0.035074583,0.024887332,0.05868095,-0.020752985,0.057256338,0.093045842,-0.038863067,-0.07084029,1.337756992,2.657346233,-6.587671126,-6.100622894,-6.888728844,-7.197893127,-6.896612762,-5.854498001,-5.416575754,-5.57364442 -3027,A183K,-0.079786219,0.070580846,0.019954089,0.035759714,-0.204094409,0.183016463,-0.013853022,-0.145719415,-0.034187436,0.090067559,0.051094132,0.032316574,0.007591604,0.069514448,0.002004979,-0.140592685,-0.267596133,1.293486817,2.263247798,-6.869062679,-5.962195663,-6.86391848,-7.370639015,-7.243000031,-6.905560204,-6.073704238,-6.128698094 -3028,A183M,-0.022916669,0.025154984,-0.010412791,0.05120098,-0.051695839,0.076707174,0.001196196,-0.047029533,0.015877991,0.002706305,0.047603662,-0.048172789,0.027347207,0.042140684,0.060261276,-0.114492745,0.011101067,1.488885611,2.430192626,-7.778223018,-7.573919891,-7.802128952,-8.486162415,-8.451562912,-6.577340919,-6.471527939,-6.348745483 -3029,A183L,0.004790857,0.015188071,0.001100767,0.034230046,-1.540338492,-0.02093112,0.043034715,-0.033453002,0.018144701,-0.006663838,0.037039979,-0.015826025,0.018027559,-0.011499587,0.079959679,-1.293096792,-1.787580191,0.66413936,1.32976294,-8.379285672,-8.860889862,-8.148057724,-8.486375633,-9.509835953,-6.891269188,-6.885983322,-6.797286955 -3030,A183N,-0.010368569,0.138499687,0.108948948,0.065015831,-0.045816636,0.13263534,0.043910236,-0.064647374,-0.014408185,0.113828454,0.163170919,0.136979355,0.08091854,0.058701579,0.071330082,-0.037761685,-0.053871587,1.263124486,2.561599786,-7.226848824,-7.335209869,-8.30918631,-8.547865791,-6.643646317,-5.298335831,-5.317554172,-5.931441132 -3031,A183Q,-0.04792725,-0.006727528,-0.005470243,0.046720674,0.0216764,0.020411749,0.002613695,-0.098468194,-0.002194047,-0.008256425,-0.00519863,0.030469296,-0.041409781,0.048577706,0.044863641,0.034903667,0.008449133,1.140736053,2.886318976,-5.783172508,-6.314887924,-5.959453949,-5.916889038,-5.36286776,-5.36176387,-4.989368692,-3.431665304 -3032,A183P,-0.00692299,0.013912668,-0.005354032,0.007483119,-1.311531959,0.01665132,0.01054576,-0.02439174,0.003817931,-0.01723911,0.045064445,-0.014249766,0.003541702,-0.02091119,0.035877427,-1.152182433,-1.470881485,0.863185041,1.362019224,-7.664703239,-7.984884499,-7.473240112,-7.646140663,-8.298527817,-6.920723106,-6.18386213,-6.558032337 -3033,A183S,0.004189247,0.020845917,0.04006587,0.052767135,0.021753514,0.086922835,0.00630405,0.002074443,-0.020718484,-0.00756658,0.049258413,0.052223007,0.027908732,0.034220469,0.071313801,-0.004006541,0.047513569,1.214737186,2.698344568,-2.80359147,-2.808798241,-2.821316719,-3.653611824,-2.900679337,-1.833551231,-2.430182466,-2.532745499 -3034,A183R,-0.044648701,0.034571484,0.025576052,0.041527768,-0.231135679,0.117625837,-0.01087788,-0.078419522,-0.040965376,0.041600222,0.027542745,0.036784646,0.014367458,0.036814457,0.046241078,-0.197768366,-0.264502992,1.379225858,2.133583363,-5.627004178,-5.356586716,-5.559105499,-5.964864937,-5.772650436,-5.481813301,-4.526437371,-5.114088888 -3035,A183T,0.009534147,0.022548666,0.017386302,0.026470988,-0.049025113,0.062015333,0.0257282,-0.006659906,-0.016233941,-0.024345646,0.069442977,0.043641877,-0.008869273,0.017900777,0.035041198,-0.055557163,-0.042493063,1.384011385,2.532897178,-4.627655847,-4.436845459,-4.38423735,-5.488062157,-5.17014843,-3.65898584,-4.357644843,-4.012949689 -3036,A183W,-0.004405637,0.001477268,0.018696625,0.049261263,-0.652367159,-0.022517626,0.005838789,-0.014650062,-0.024290331,-0.027612752,0.030567288,0.029769385,0.007623865,0.032395928,0.066126597,-0.505342675,-0.799391643,0.657164259,1.425774123,-9.324683206,-9.037518616,-9.63349144,-10.18596162,-9.498445976,-8.267998375,-7.37028396,-7.468670416 -3037,A183V,-0.021128738,0.003535019,-0.00441787,0.02467123,0.016607528,-0.013892602,-0.029002046,-0.013255429,0.020636236,0.023558025,-0.016487987,0.031436545,-0.040272284,0.023680887,0.025661572,0.008400803,0.024814252,1.008546763,2.519511482,-5.494781104,-5.139751915,-5.945951309,-5.907063004,-6.228166946,-4.252972343,-4.836063896,-4.851513624 -3038,A183Y,-0.089999149,-0.032048744,-0.005827854,0.030016786,-0.110270561,0.063862655,0.025528348,-0.205526645,-0.019529004,-0.035800692,-0.028296795,0.049182426,-0.060838133,0.104902001,-0.04486843,-0.077621385,-0.142919737,1.565538519,2.750917772,-8.983895396,-8.474588554,-9.314401512,-10.04879456,-9.276488579,-7.805203774,-7.167898959,-7.003888666 -3039,M184A,-0.007670949,-0.020116936,0.006407441,-0.002802814,-1.621073773,0.022686319,0.000236271,-0.015578169,-0.00586538,-0.070231697,0.029997825,-0.06894379,0.081758671,-0.044599555,0.038993928,-1.510267403,-1.731880143,0.817772387,1.328862368,-4.038409366,-2.821572563,-2.267180717,-4.046127434,-6.943618622,-4.113547493,-2.75325925,-1.76688287 -3040,M184C,-0.020024225,-0.029760362,-0.047118316,-0.133387095,-1.715535123,0.023287305,-0.013314856,-0.026733593,-0.008535606,-0.095538359,0.036017635,-0.123292216,0.029055584,-0.183234456,-0.083539733,-1.8585895,-1.572480745,1.270773314,1.342290174,-10.57965297,-10.12723325,-10.21311843,-11.12700714,-11.11027993,-10.32062612,-6.64778528,-4.144856523 -3041,M184E,-0.025726777,-0.538535152,-1.883190287,-2.140533894,-3.163032745,-0.01911326,-0.031310591,-0.020142962,0.049525513,-0.556608357,-0.520461947,-2.005917932,-1.760462641,-2.110375725,-2.170692063,-3.041859344,-3.284206146,1.344979288,-0.138641063,-11.82663974,-10.08517387,-11.18203423,-12.73722656,-13.23491512,-11.89384892,-8.477782357,-7.311449822 -3042,M184D,-0.022784556,-1.461136577,-2.117561804,-2.373392185,-3.260115432,-0.01331702,-0.008812968,-0.036756143,0.043490789,-1.81738331,-1.104889844,-2.016815411,-2.218308197,-2.280974047,-2.465810322,-3.098514313,-3.421716551,-0.898669331,-1.084774251,-12.72151038,-11.70678309,-12.25896468,-13.55826331,-13.52048732,-12.5630535,-8.455645721,-7.311449822 -3043,M184G,-0.009993944,-0.071870612,-1.236829301,-2.288690503,-2.794416557,-0.001076434,-0.006959731,-0.013028156,-0.013340952,-0.134843138,-0.008898086,-1.329074046,-1.144584556,-2.365780054,-2.211600951,-2.732992243,-2.855840871,0.940209545,0.09253781,-11.56411057,-10.72810131,-10.15459177,-12.20526958,-12.80588436,-11.92670584,-7.603322852,-6.429024149 -3044,M184F,-0.003377559,-0.072998573,0.006555257,0.003948701,-0.249223794,-0.039049432,-0.028332662,0.021577545,0.015121633,-0.171233822,0.025236677,-0.021863146,0.03497366,-0.033017138,0.04091454,-0.247929337,-0.25051825,1.140336024,1.814768816,-8.373350099,-8.203760658,-7.468840767,-10.22778327,-9.080827873,-6.885537926,-4.658352266,-2.37067667 -3045,M184I,-0.044003885,-0.03799069,-0.021033345,-0.023959977,-0.030925581,-0.024640397,-0.081307886,-0.006699883,-0.004753877,-0.101752871,0.025771492,-0.104831404,0.062764714,-0.083067462,0.035147509,-0.102937858,0.041086696,1.487893931,2.280312823,-2.683348854,-3.096134056,-1.602787537,-2.588182571,-2.91251609,-3.217124016,-2.641580762,-1.215989802 -3046,M184H,-0.027584913,0.008232975,-0.784877343,-2.156968421,-2.983621742,-0.035995858,-0.04206656,-0.013103265,0.034128337,-0.045686038,0.062151987,-0.862306324,-0.707448361,-2.107441723,-2.206495118,-3.071110025,-2.896133459,1.913922173,0.740252278,-12.61571819,-11.68289847,-11.76393416,-14.61086838,-13.69763052,-11.3232594,-7.318412139,-5.511316138 -3047,M184K,-0.006939745,-0.210010719,-1.462295766,-2.250184896,-3.088453138,-0.035299311,0.000431732,-0.014311221,-0.006877716,-0.312757247,-0.107264191,-1.606194371,-1.318397161,-2.268293015,-2.232076776,-2.988923269,-3.187983006,1.382772735,0.101620915,-11.11077219,-10.32923153,-10.69055606,-12.16669569,-11.16723736,-11.2001403,-8.124188417,-7.246977239 -3048,M184L,-0.030075035,-0.028226341,-0.006117206,-0.006625001,-1.189826062,0.055857884,-0.009336543,-0.050813526,-0.042033468,-0.090175291,0.033722609,-0.044139541,0.031905129,-0.066414144,0.053164143,-0.947066346,-1.432585777,1.018525895,1.422827172,-5.231478915,-3.501310501,-6.823992615,-6.018652817,-3.911836884,-5.901601761,-4.071945976,-0.69792654 -3049,M184N,-0.023103461,-0.086900743,-1.345229326,-2.779819234,-2.641933471,0.009281224,-0.00953136,-0.036675562,-0.016386015,-0.124876011,-0.048925474,-1.446220394,-1.244238258,-2.965651535,-2.593986932,-2.783191802,-2.500675139,0.855042648,0.059992314,-13.68347434,-13.30268517,-14.36115207,-14.4030263,-13.54781538,-12.80269277,-9.3260893,-9.664162641 -3050,M184Q,0.000468201,-0.00638453,-0.002617526,-1.22788001,-2.403221462,-0.015237537,0.011237495,-0.010301094,0.037093219,-0.118413305,0.105644246,-0.064507401,0.059272349,-1.050525125,-1.405234894,-2.399544309,-2.406898615,1.151133394,0.830686873,-9.331905232,-7.500102577,-10.04270785,-9.598024231,-10.18674187,-9.331949631,-6.468126871,-3.659458868 -3051,M184P,-0.033028056,-1.165859538,-2.190393164,-2.459885108,-3.030596748,0.023086796,-0.028939626,-0.037116485,0.034720581,-1.404563305,-0.927155771,-2.441268109,-1.939518219,-2.404396749,-2.515373466,-2.823997007,-3.237196489,-0.340546978,-0.894739244,-12.56093716,-11.8125698,-11.99774866,-13.22729124,-13.44295313,-12.32412296,-9.3260893,-9.664162641 -3052,M184S,-0.036268838,-0.050471957,-0.144130785,-1.646338608,-2.663571844,-0.031259726,-0.031543918,-0.040993757,-0.001026068,-0.065144434,-0.035799479,-0.206947256,-0.081314314,-1.486618058,-1.806059157,-2.50045297,-2.826690717,1.320393414,0.787536766,-8.532345021,-7.717809944,-7.782505623,-9.483253288,-8.882892715,-8.795263535,-5.336343538,-3.508296399 -3053,M184R,-0.026353005,-0.982419905,-2.055137769,-2.383815128,-3.190159524,0.001603937,-0.021947307,-0.030758702,0.063149733,-1.169817145,-0.795022664,-2.178434731,-1.931840807,-2.388235704,-2.379394552,-2.658073642,-3.722245406,0.283237066,-0.715703706,-13.02766366,-12.08396581,-13.78701694,-13.48815012,-13.62352993,-12.1556555,-9.3260893,-9.664162641 -3054,M184T,-0.028301439,-0.022840129,-0.208308256,-1.775472161,-2.579511712,-0.034067697,-0.040733128,-0.015869749,0.031913636,-0.082711278,0.03703102,-0.279519236,-0.137097276,-1.80954345,-1.741400871,-2.706264963,-2.452758461,1.406133536,0.745639051,-7.814627203,-8.25908773,-6.546794952,-8.056327797,-8.676142319,-7.534783218,-5.65910034,-2.945930287 -3055,M184W,-0.027345065,-0.426407951,-1.856941516,-2.3239542,-2.987315471,0.077876249,-0.025250714,-0.029439415,-0.034900461,-0.514191653,-0.338624248,-2.059732125,-1.654150906,-2.113037395,-2.534871004,-3.044521014,-2.930109927,1.28670345,-0.16612846,-11.20513373,-10.83834392,-11.13614493,-11.35315315,-12.77808223,-9.919944443,-5.935094891,-4.689412066 -3056,M184V,-0.010718105,-0.003280458,0.000209717,0.018757403,-0.284368235,0.021091874,-0.003974027,-0.017462183,-0.010998272,-0.056504166,0.049943251,-0.052838556,0.05325799,-0.018361894,0.0558767,-0.301096378,-0.267640091,1.743961512,2.278832726,-3.997260645,-3.629079544,-3.247514778,-3.871363022,-4.074196632,-5.164149246,-3.215703332,-2.117353853 -3057,M184Y,-0.041376596,-0.000320622,0.033301208,-0.005854532,-0.496208612,-0.023330057,-0.047050813,-0.035702379,-0.058189134,-0.038450251,0.037809008,0.010090914,0.056511502,0.002429874,-0.014138938,-0.433090529,-0.559326694,1.281431829,1.724732943,-10.32741354,-10.45575513,-8.924756996,-11.72473989,-11.73938422,-8.79243148,-5.635672965,-2.902225013 -3058,A185C,-0.008064639,-0.015629525,0.031268952,-0.001776638,-1.555559949,-0.022926801,-0.011571598,-0.00455768,-0.110207351,-0.029697519,-0.001561531,0.047631229,0.014906675,-0.012775029,0.009221754,-1.253067441,-1.858052456,0.638849258,1.327233339,-6.925337575,-7.786796799,-7.493366028,-5.923378067,-5.297143753,-8.126003227,-5.859515987,-3.470996241 -3059,A185E,-0.004151671,-0.91591615,-2.07866261,-2.316155505,-2.788667675,-0.041549822,-0.015255826,0.006952485,0.078265061,-1.059552997,-0.772279303,-2.255501176,-1.901824044,-2.74222049,-1.890090519,-2.613916138,-2.963419211,0.238378602,-0.673580413,-7.930037503,-8.338119995,-8.137184494,-7.271108673,-7.216540054,-8.687234299,-6.779089594,-4.659426992 -3060,A185D,-0.020693382,-1.175518417,-1.971747094,-2.398618334,-2.268067522,-0.038378169,-0.02332981,-0.018056953,-0.040565306,-1.359426415,-0.991610419,-2.266579055,-1.676915132,-2.57720711,-2.220029558,-2.448902759,-2.087232285,0.297067642,-0.839832726,-8.602338284,-9.410581772,-9.463603912,-7.737253326,-7.335609337,-9.064643074,-7.83767217,-4.939334003 -3061,A185G,-0.033608634,-0.023681149,-0.024861984,-0.045160985,-0.050523955,-0.011851244,-0.047961102,-0.019256165,-0.040461599,-0.048215725,0.000853427,-0.023197419,-0.026526549,-0.047012735,-0.043309234,-0.042079604,-0.058968306,1.456724113,2.579772302,-5.233072729,-6.37270459,-6.846177483,-4.355751785,-3.826286987,-4.764442802,-5.808182848,-1.137568871 -3062,A185F,-0.06493873,-1.415873215,-2.236333583,-2.552280449,-2.844278657,-0.000787994,-0.02389632,-0.105981139,-0.074181464,-1.718448358,-1.113298071,-2.391517792,-2.081149373,-2.048933333,-3.055627564,-2.749932754,-2.938624559,0.087895735,-1.042675868,-10.71206912,-9.965279526,-11.06526134,-9.622275307,-9.313538132,-13.5939913,-7.98141515,-5.450003425 -3063,A185I,-0.053221543,-0.017483213,-0.03144166,-1.630652641,-2.614938872,-0.080200214,-0.052120276,-0.054322809,-0.018175191,0.013743452,-0.048709878,-0.020952832,-0.041930487,-1.603422493,-1.657882788,-2.952239396,-2.277638347,0.46976688,0.686914982,-5.499524615,-4.631050873,-5.399659584,-4.525361,-5.512922478,-7.428629143,-6.190670563,-2.946994895 -3064,A185H,-0.026853823,-1.124137082,-2.206725087,-2.562262576,-3.069942666,0.000257749,-0.013227433,-0.040480212,-0.078561555,-1.249742114,-0.998532049,-2.263350085,-2.150100089,-2.397886881,-2.726638271,-2.700946294,-3.438939038,0.549557098,-0.756004179,-8.51190275,-8.380955963,-8.488374382,-7.780150856,-7.304434746,-10.6055978,-7.814952449,-5.529414251 -3065,A185K,-0.044404121,-0.967414141,-2.224323459,-2.69690255,-3.172889151,-0.033649068,-0.039407315,-0.049400927,0.076564537,-1.027973382,-0.906854899,-1.810187286,-2.638459631,-2.05386855,-3.33993655,-2.946753498,-3.399024804,3.329143776,1.293001436,-8.697672058,-8.854885094,-7.83964267,-7.523911064,-8.472442329,-10.79747913,-8.405112174,-5.710008152 -3066,A185M,-0.037122277,0.01843216,-0.493661259,-2.103042371,-2.928513973,0.004858197,-0.02067364,-0.053570914,0.052393596,-0.02263114,0.059495459,-0.472075567,-0.51524695,-2.02574167,-2.180343071,-2.471468586,-3.38555936,1.51617317,0.709779293,-6.6747547,-7.433013283,-7.203390739,-5.989738045,-6.417787186,-6.329844246,-6.124946944,-2.839616983 -3067,A185L,-0.050203683,-0.000365706,-1.198012566,-2.240915612,-3.00665791,-0.030173362,-0.043459405,-0.05694796,-0.032914345,-0.003576252,0.002844841,-1.247315677,-1.148709455,-2.195916279,-2.285914944,-2.927949934,-3.085365886,0.867067265,0.106191403,-4.611370105,-4.678468521,-4.341564697,-3.827806618,-5.005861122,-5.203149567,-3.730377582,-1.732657758 -3068,A185N,-0.049408828,-0.729591809,-2.07579401,-2.857723933,-2.973630882,-0.027906553,-0.047644932,-0.051172723,-0.03410538,-0.753878096,-0.705305521,-2.183909482,-1.967678538,-2.971658791,-2.743789075,-2.542324444,-3.40493732,0.235418999,-0.576251362,-6.39444984,-7.081490517,-8.409150856,-5.393446167,-5.575910835,-5.512250824,-5.721806907,-2.495635276 -3069,A185Q,-0.00943856,-0.564634195,-2.091161466,-2.396513682,-2.960545912,-0.071781564,-0.029400353,0.010523234,0.035638584,-0.623912842,-0.505355547,-2.207759092,-1.974563839,-2.643325883,-2.14970148,-2.691112791,-3.229979033,0.507321003,-0.506561001,-7.547681737,-7.036175034,-6.932364204,-6.854644524,-7.496833801,-9.418391121,-7.101597588,-5.147896147 -3070,A185P,-0.038933121,-1.028195166,-2.125714051,-2.448576657,-3.129075266,-0.011473812,-0.033977158,-0.043889084,-0.031293691,-1.163013578,-0.893376753,-2.195104956,-2.056323145,-2.361826434,-2.535326879,-3.04643544,-3.211715091,0.408720348,-0.707009459,-10.02304055,-10.2672103,-10.45693192,-9.108223228,-9.039528069,-11.24330923,-10.00900564,-9.530625902 -3071,A185S,-0.026151158,0.006481436,0.000791007,-0.007999524,-0.573427357,-0.007586402,-0.031590272,-0.020712043,-0.073491689,-0.006798891,0.019761763,-0.006987066,0.008569079,-0.044126062,0.028127015,-0.448140169,-0.698714545,1.145803503,1.644005066,-3.376056349,-3.721343674,-4.319970116,-2.883989937,-3.229033661,-2.725944359,-3.851295797,-2.557189153 -3072,A185R,-0.050095819,-1.282575989,-2.201716557,-2.42638156,-2.414795069,0.080328571,-0.050202208,-0.049989429,-0.035764395,-1.454712028,-1.11043995,-2.185773409,-2.217659705,-2.382458111,-2.470305008,-2.26543477,-2.564155368,0.070988724,-0.912108004,-6.397883322,-5.622271317,-5.301867157,-6.100722572,-6.572227814,-8.392327751,-6.443756131,-4.894628797 -3073,A185T,-0.020096463,0.004536392,-0.056177994,-1.694488166,-2.386208396,-0.052809244,-0.026372263,-0.013820663,-0.019255994,-0.031485609,0.040558393,-0.078287711,-0.034068277,-1.613984507,-1.774991824,-2.420178607,-2.352238184,0.892366569,0.707705154,-3.322105244,-3.646137421,-4.142583122,-2.257168938,-3.840589615,-2.724047127,-4.44948227,-1.362813681 -3074,A185W,-0.00907795,-1.292192313,-2.252573029,-2.886261769,-2.866635331,-0.033356176,-0.011605388,-0.006550511,-0.038710903,-1.411333576,-1.173051049,-2.300002811,-2.205143247,-3.212690857,-2.55983268,-2.959447769,-2.773822893,0.27502411,-0.882451424,-11.56765105,-11.57636394,-11.34360201,-10.78717826,-10.17638213,-13.95472892,-10.00900564,-9.53062648 -3075,A185V,-0.065968972,0.008271694,0.002944159,-0.021148135,-1.607457871,0.018005252,-0.066515651,-0.065422293,-0.046976621,-0.002879092,0.019422479,0.036209932,-0.030321614,-0.036374049,-0.005922221,-1.446091781,-1.768823961,0.718621735,1.325075583,-2.656834207,-1.964291191,-1.653731812,-2.671388008,-3.002632271,-3.992127754,-3.551506633,-1.019197891 -3076,A185Y,-0.070438859,-1.39081188,-2.080228795,-2.207800306,-3.131419231,-0.049347728,-0.082046765,-0.058830952,-0.001874672,-1.620451249,-1.161172511,-1.904354599,-2.256102991,-2.361110689,-2.054489922,-3.107867601,-3.154970861,-0.085751977,-0.99298802,-11.55339915,-11.13989272,-12.30900917,-10.03907424,-9.062355415,-15.21666421,-8.032344806,-5.02162522 -3077,T186A,-0.051869976,0.045460022,0.022103353,0.019967522,0.049039139,0.006832653,-0.01862022,-0.085119731,0.017509642,0.048129118,0.042790926,0.029332633,0.014874072,0.023740781,0.016194263,0.010059428,0.08801885,1.174553362,2.599651906,0.484448805,0.822616997,0.671510292,1.017834297,-0.139738098,0.050020538,-1.174869371,0.172016602 -3078,T186C,-0.003947181,0.060716979,0.021746003,0.049231988,0.066228188,0.03980164,0.045529917,-0.053424278,0.015723895,0.013609439,0.107824518,0.061899266,-0.01840726,-0.027223434,0.125687409,-0.005087652,0.137544028,1.367594346,2.688442191,-3.574554997,-3.79519857,-3.751854324,-3.790543877,-3.135290466,-3.399887749,-4.85899242,-3.478068506 -3079,T186E,-0.066428256,0.083985966,-0.015274966,0.050377796,0.062168248,0.014513931,-0.050886066,-0.081970445,-0.008633107,0.164421845,0.003550087,0.067833651,-0.098383583,0.103589213,-0.002833622,0.11213737,0.012199126,1.093728841,3.008726175,0.161197,-0.338675629,0.814278214,0.752693924,-0.322283356,-0.100028152,-1.852064681,-0.395577875 -3080,T186D,-0.063389962,0.093074711,0.090156663,0.029048849,0.127180098,-0.037177426,-0.077159019,-0.049620905,0.02736536,0.10985126,0.076298162,0.108646558,0.071666767,0.121029369,-0.062931672,0.16509674,0.089263455,1.047541235,3.116286293,-0.603712874,-1.476095177,0.540075798,0.121780441,-1.443048759,-0.761276672,-2.480340976,-0.433399608 -3081,T186G,-0.034743433,0.057712496,0.017675864,0.044081295,0.057716959,0.034046834,0.001447593,-0.070934459,-0.015302374,0.029192147,0.086232845,0.025864204,0.009487523,0.024008242,0.064154348,0.032459925,0.082973993,1.093682069,2.713746065,-0.345775545,-0.557374542,-0.501538811,-0.295958267,-0.559746277,0.185740173,-1.676955238,-0.531908604 -3082,T186F,-0.072259767,0.032396121,0.009118899,0.037443919,0.038390944,0.07914307,-0.006833226,-0.137686308,0.072399927,0.040463713,0.024328529,0.015884527,0.002353271,0.069378073,0.005509765,0.038915632,0.037866255,1.211466628,2.848028856,-4.271186082,-4.07816922,-5.119311714,-5.451313118,-3.280236877,-3.426899483,-4.152174097,-3.135975113 -3083,T186I,0.021356632,0.025422112,0.016256139,0.047038095,0.064125918,-0.02824627,0.053553192,-0.010839928,0.050879739,-0.04188758,0.092731804,-0.101665393,0.134177671,-0.02838601,0.1224622,-0.005916485,0.13416832,1.099551109,2.37430939,-3.529019539,-3.627907455,-3.80451931,-4.358497581,-2.017423203,-3.836750145,-5.146665032,-1.579001783 -3084,T186H,-0.041207175,0.034109373,0.032269542,0.013930269,0.078777168,0.005116248,-0.010753137,-0.071661212,-0.001585156,0.004466059,0.063752687,0.024053316,0.040485767,0.015148377,0.012712161,0.039483708,0.118070627,1.105856703,2.705501758,-1.052583203,-1.112644081,-1.151012047,-0.656309639,-1.018484474,-1.324465775,-2.137350909,-1.478939884 -3085,T186K,-0.102015287,0.045586778,-0.013633772,0.023359639,0.063526439,0.088081481,-0.083129967,-0.120900607,-0.029071411,0.089896255,0.0012773,0.011802104,-0.039069648,0.037241899,0.009477379,0.036437058,0.09061582,0.914327247,2.593112217,0.785576387,0.78230719,0.981446442,0.710252846,0.973632668,0.48024279,-0.213029154,-0.411428136 -3086,T186M,0.000650066,0.02992557,0.056394089,0.043284625,0.079871209,-0.003534489,0.004061615,-0.002761484,0.026397969,-0.008897902,0.068749042,0.033328719,0.079459459,0.055882826,0.030686423,0.083128014,0.076614404,1.065872171,2.817042518,-2.628861229,-2.314705551,-2.88108889,-3.707138626,-1.49124218,-2.750130898,-3.583074401,-1.905964542 -3087,T186L,-0.065299913,0.020081622,-0.006086841,0.03090952,0.04893101,0.027334715,-0.029106494,-0.101493332,0.022704417,0.01896793,0.021195314,0.011792839,-0.023966521,0.053318427,0.008500613,0.056878482,0.040983538,1.075634088,2.727779521,-2.104693701,-2.288436127,-2.697402138,-2.920768181,-0.377654083,-2.239207977,-3.460971288,-0.518502987 -3088,T186N,-0.071777942,0.05211263,0.08587661,0.061358267,0.079541488,-0.035514591,-0.059732471,-0.083823413,-0.081263858,0.088012111,0.016213149,0.162939704,0.008813516,0.132842612,-0.010126078,0.041183493,0.117899483,1.054378671,2.949401794,-0.658452061,-1.350761604,-0.100607605,-0.248484322,-0.536696457,-1.05571032,-2.952713819,-1.01915564 -3089,T186Q,-0.10242923,0.035523835,-0.034164405,0.025031605,0.070922127,0.048529296,-0.092377729,-0.112480731,0.031397836,0.095576858,-0.024529188,0.029353077,-0.097681886,0.089860969,-0.039797759,0.111722482,0.030121772,1.172783769,3.065299393,0.544088359,0.503160233,0.932826546,0.706571724,0.442268257,0.135615036,-0.861570435,-0.502303855 -3090,T186P,-0.067149865,0.015478685,-0.002556131,0.013835222,-0.979858789,0.0031999,-0.028449991,-0.105849738,0.010703568,0.017749551,0.013207819,0.015638425,-0.020750687,0.016293195,0.011377249,-0.735377516,-1.224340061,0.813136308,1.412826818,-5.644749071,-5.372252258,-5.516104813,-5.763138512,-5.723278572,-5.848971199,-7.398013917,-7.348989366 -3091,T186S,-0.052794932,0.024468739,0.008346544,0.016023882,0.026542246,0.046891017,-0.01644739,-0.089142473,0.001812102,0.003935461,0.045002016,0.017271761,-0.000578673,0.009914256,0.022133507,-0.026285599,0.07937009,1.222203606,2.476145037,-0.071429585,0.034095657,0.287556595,0.043139015,-0.315808983,-0.406130211,-1.260373269,-0.78574134 -3092,T186R,-0.073916062,0.041397571,0.043679866,0.022182927,0.069973766,0.178230614,-0.035176676,-0.112655448,-0.119131797,0.009543161,0.073251981,0.066898503,0.020461228,-0.004364529,0.048730382,0.030740937,0.109206594,1.191079577,2.647570344,0.592316081,0.820371002,0.797429146,0.694061943,0.625207077,0.024511238,-0.665725105,0.513679868 -3093,T186W,-0.090625429,-0.023354781,0.002000884,0.009366323,0.043396619,-0.046948307,-0.072996378,-0.108254479,-0.00713912,-0.065802754,0.019093193,0.009552085,-0.005550318,-0.001855962,0.020588608,0.039622217,0.04717102,1.177658364,2.682016338,-4.575853694,-4.181471771,-4.871396904,-4.893232742,-4.359967758,-4.573199295,-4.890736925,-4.206858001 -3094,T186V,-0.074503351,0.075607992,0.020407679,0.061884914,0.055647606,-0.00881407,-0.055784109,-0.093222592,0.020132501,0.058163341,0.093052642,0.01586424,0.024951118,0.046139341,0.077630487,0.028994822,0.082300389,1.043677402,2.540254647,-2.964307373,-3.167943871,-2.988708252,-3.000943367,-2.301949387,-3.361991989,-4.53795547,-1.844081214 -3095,T186Y,-0.100819698,0.066725468,0.037632009,0.024546971,0.077859825,0.120519686,-0.047504386,-0.15413501,0.026340678,0.025261854,0.108189082,0.035209061,0.040054957,0.025928157,0.023165785,0.017049813,0.138669837,1.168068201,2.634443941,-3.600423315,-2.916757423,-4.68752562,-4.620640617,-2.942760658,-2.834432259,-4.964998369,-2.772582273 -3096,T187A,-0.00247782,0.039782501,-0.012975846,-0.015191217,-0.499151566,0.021077328,-0.033023342,0.028067703,0.019778847,0.069952977,0.009612024,0.014187423,-0.040139115,0.007500955,-0.037883389,-0.382638709,-0.615664422,0.94998541,1.589895383,-5.634194075,-4.914493683,-4.211839371,-8.131749725,-4.743877937,-6.169009659,-5.623722256,-1.641598925 -3097,T187C,-0.071034633,0.001795653,-0.010014803,-0.093694775,-0.854236268,0.010845488,-0.068661571,-0.073407695,0.004970949,-0.009984221,0.013575526,-0.00540218,-0.014627425,-0.143273954,-0.044115595,-0.646480163,-1.061992373,1.583238906,1.798166183,-9.353331291,-8.838002022,-11.00442151,-10.29617422,-9.367192528,-7.26086618,-6.83266191,-2.127619604 -3098,T187E,-0.007346303,-0.023657093,-0.063929331,-1.530928188,-2.552683678,0.003631817,-0.076063279,0.061370673,0.071236613,-0.001711695,-0.04560249,-0.051017837,-0.076840824,-1.362585279,-1.699271096,-2.476767615,-2.628599741,1.14938596,0.768007662,-12.44105987,-12.02727456,-12.56591955,-13.73394483,-11.56198572,-12.31617468,-10.52248242,-8.511017341 -3099,T187D,-0.109269711,0.004138091,-0.038010397,-0.050844883,-0.08524659,-0.026128071,-0.130399481,-0.088139941,0.05954527,0.065736493,-0.057460312,0.06976494,-0.145785734,0.043844296,-0.145534062,-0.017590605,-0.152902574,1.276624209,2.673779753,-8.618710542,-8.200002617,-9.028312225,-9.45363208,-6.600597092,-9.811008698,-4.916491759,-0.573999519 -3100,T187G,0.005888362,0.028210136,0.005550578,-0.016230804,-0.691341429,-0.008837448,-0.040428542,0.052205266,0.05573892,0.06085368,-0.004433408,-0.000657488,0.011758644,-0.006661135,-0.025800472,-0.519989185,-0.862693672,0.810773139,1.462812543,-8.435471208,-7.984572281,-8.507582932,-9.15159565,-7.404895226,-9.128709953,-6.18495103,-1.686280785 -3101,T187F,-0.045404998,0.070057506,0.054481834,-0.016548101,-1.822937331,0.116017292,-0.035963318,-0.054846678,-0.014904866,0.100321464,0.039793548,0.101295073,0.007668595,-0.050750212,0.01765401,-1.549508596,-2.096366066,0.546933241,1.311451869,-11.68199432,-8.817125267,-15.0091776,-11.23387903,-14.90722314,-8.442566559,-6.008612364,-1.136603201 -3102,T187I,-0.087644625,0.06491658,-0.006978818,-0.013895846,-0.578642539,0.046294451,-0.095478441,-0.079810809,0.018106997,0.139530144,-0.009696985,0.050453024,-0.06441066,0.008609145,-0.036400837,-0.347625328,-0.80965975,1.958966849,2.392367641,-7.838811961,-6.309117737,-8.395758942,-9.45207238,-9.469714508,-5.56739624,-6.649019214,-0.973735897 -3103,T187H,-0.070539448,0.035037287,-0.004869834,-0.063882873,-2.217539756,0.078425123,-0.050767101,-0.090311795,0.039321055,0.084465194,-0.01439062,0.014707427,-0.024447095,-0.034762106,-0.09300364,-1.87840377,-2.556675742,0.733812258,1.303687588,-10.96309934,-10.60261366,-11.87996316,-11.45931833,-12.71336178,-8.160239792,-7.538904772,-3.995165884 -3104,T187K,-0.164605587,-0.017233508,-0.76751297,-1.220236386,-1.628477245,0.312785115,-0.165672651,-0.163538522,-0.193737531,0.02780434,-0.062271356,-0.883491656,-0.651534283,-1.42833731,-1.012135461,-2.103186952,-1.153767538,3.518192136,2.326351641,-12.34111129,-11.47459217,-13.63994494,-13.22905772,-11.66102549,-11.70093615,-10.52248242,-8.511017341 -3105,T187M,-0.03789987,0.006222499,0.00339993,-0.079470755,-0.569884531,0.160854507,0.0101835,-0.08598324,0.027327036,0.061815072,-0.049370075,0.039191324,-0.032391465,-0.029909603,-0.129031906,-0.451277649,-0.688491412,0.959063084,1.574091243,-7.102944997,-5.07657222,-8.514319336,-9.59433474,-7.230271889,-5.099226799,-6.205544515,-1.775200634 -3106,T187L,-0.014389416,0.050198374,-0.005782841,-0.054315929,-0.484891115,0.050405089,-0.04410138,0.015322548,0.027864675,0.083755745,0.016641003,-0.018472331,0.00690665,-0.058426024,-0.050205834,-0.370793193,-0.598989036,1.080823056,1.662594168,-7.337082472,-5.390972168,-9.141583481,-11.09317932,-6.736283051,-4.323394341,-5.621029696,1.004514833 -3107,T187N,0.146835362,0.067705494,0.030860622,0.04392771,-0.067171304,0.01446211,0.12653248,0.167138244,0.101735352,-0.061136743,0.196547731,-0.101527436,0.163248679,-0.089954607,0.177810026,-0.09348431,-0.040858297,1.486246105,2.372658463,-6.31453383,-5.43627301,-8.000293449,-7.456643173,-5.591130432,-5.088329086,-4.725936791,-1.190166687 -3108,T187Q,-0.057097797,0.045594699,-0.011872908,-0.120521637,-1.690890002,0.106282974,-0.091896611,-0.022298982,0.024193715,0.080893827,0.01029557,-0.01926124,-0.004484575,-0.168101385,-0.072941888,-1.569949756,-1.811830248,1.197762193,1.366751842,-11.045627,-10.65344155,-11.32566238,-13.50242733,-10.0721,-9.674503716,-8.349604386,-5.174145708 -3109,T187P,-0.001175072,-1.050907629,-1.950785722,-2.039223573,-2.552642805,-0.053135729,-0.039772043,0.037421899,0.071267539,-1.216952046,-0.884863211,-1.955434493,-1.94613695,-2.019881182,-2.058565963,-2.67245443,-2.43283118,-0.124319066,-0.752173615,-12.38872204,-11.6507423,-12.59283674,-13.80863772,-11.78758199,-12.10381147,-10.27555753,-7.529400929 -3110,T187S,-0.033943103,0.040858867,-0.0000738,-0.027495826,-0.072998047,-0.014013937,-0.061315972,-0.006570234,0.068185862,0.078998424,0.00271931,0.003616989,-0.003764528,-0.007224626,-0.047767026,-0.030307517,-0.115688576,1.264820319,2.529098747,-2.890523331,-1.989547256,-3.829096619,-3.81862928,-2.182986305,-2.632357193,-3.757538335,-0.367713813 -3111,T187R,-0.091547208,0.092933389,-0.854442922,-1.548821226,-1.94747267,0.374884577,-0.095000715,-0.088093701,-0.117813686,0.152287411,0.033579366,-0.786664929,-0.922220914,-1.429797124,-1.667845328,-1.882798018,-2.012147321,3.684799179,2.590349861,-12.58155176,-12.47559785,-12.19292096,-15.21236257,-12.16538672,-10.86149071,-10.48853256,-8.361566337 -3112,T187W,-0.01087169,0.117279266,0.047987627,-0.769282456,-2.333350456,0.250103139,-0.021242058,-0.000501321,-0.113284888,0.161086237,0.073472294,0.059920006,0.036055247,-0.452489709,-1.086075203,-1.950160997,-2.716539915,1.599059053,1.379448433,-13.98684379,-12.33460432,-16.64228416,-13.98215629,-14.7090305,-12.26614365,-8.336045424,-4.891284924 -3113,T187V,-0.023786055,0.023386524,-0.001549652,-0.034999675,-0.670291875,0.001823534,-0.054522199,0.006950089,0.057510723,0.031851848,0.0149212,0.009326257,-0.01242556,-0.032733637,-0.037265713,-0.478111614,-0.862472136,1.152846942,1.645244153,-7.383042337,-5.052011406,-7.005811966,-8.829811539,-8.241655693,-7.785921082,-6.647229316,-1.533883139 -3114,T187Y,-0.048593952,0.135146638,-0.057504944,-1.500922422,-2.430647819,0.252472354,-0.00845919,-0.088728713,0.001082879,0.156076697,0.114216579,-0.056365277,-0.058644611,-1.171086238,-1.830758605,-2.447995873,-2.413299764,0.8825504,0.754023055,-14.32132197,-13.32496182,-16.86227638,-13.29797762,-16.16295296,-11.95844106,-7.684766806,-2.766768301 -3115,L188A,-0.020518577,-0.052350189,-0.05527152,-0.062904802,-1.20747049,-0.075153104,-0.046622712,0.005585559,-0.006119916,-0.060093618,-0.044606759,-0.059171514,-0.051371525,-0.092712224,-0.033097379,-0.877754209,-1.537186771,1.175719652,1.485322417,-8.627420511,-8.663883156,-8.856683136,-8.760536392,-6.899074181,-9.95692569,-6.195895843,-4.571648911 -3116,L188C,0.021918244,-0.052956088,-0.026166818,-0.005878017,-1.090092962,-0.096717444,0.019482641,0.024353846,-0.00494145,-0.121542452,0.015630277,-0.045804252,-0.006529383,-0.059718766,0.047962733,-0.891695129,-1.288490795,0.931135161,1.41377584,-10.08544011,-10.94043574,-9.791555687,-11.53817464,-9.051717506,-9.105316994,-7.458772022,-5.984954223 -3117,L188E,-0.022292077,-0.337516945,-1.580114639,-2.395993134,-3.037699413,-0.070355423,-0.025349952,-0.019234201,0.013105023,-0.242729916,-0.432303973,-1.500183244,-1.660046034,-2.391110911,-2.400875357,-3.033144902,-3.042253924,1.224224992,0.098449606,-12.59703572,-12.99192192,-13.12778668,-12.95171986,-11.37201019,-12.54173992,-9.916627407,-10.2655079 -3118,L188D,0.018427904,-0.725098006,-1.965789216,-2.222618055,-2.713809337,-0.116255625,0.000604229,0.036251579,0.066058042,-0.634352802,-0.81584321,-2.192836126,-1.738742305,-2.20870253,-2.23653358,-2.549706526,-2.877912147,0.562929814,-0.504970305,-12.94877676,-13.50833361,-13.31924121,-13.49938637,-11.54755515,-12.86936745,-9.916627407,-10.2655079 -3119,L188G,0.004024969,-0.027412995,-0.011802058,-1.436427566,-2.153407982,-0.086507109,-0.010374028,0.018423966,0.01773789,-0.019159186,-0.035666803,-0.018737619,-0.004866496,-1.321027287,-1.551827844,-2.127481734,-2.17933423,0.774853537,0.725128787,-11.69772429,-12.84238483,-11.6938976,-12.25401973,-10.3673688,-11.33095048,-8.432711413,-6.649699156 -3120,L188F,-0.046343314,-0.080928885,-0.10571058,-0.05404149,-0.129732593,-0.083994914,-0.0755392,-0.017147427,0.062353263,-0.074197938,-0.087659832,-0.065976001,-0.145445159,-0.084635304,-0.023447675,-0.102753399,-0.156711786,1.364145129,2.229929175,-7.138384087,-7.616309631,-5.880091156,-9.047303154,-5.896759529,-7.251456963,-5.608337288,-2.217248718 -3121,L188I,0.021721432,0.022037183,0.017778982,0.048551418,0.057770815,-0.152550278,0.019313402,0.024129462,0.071580379,0.09205545,-0.047981085,0.13687119,-0.101313227,0.140659475,-0.043556639,0.130392401,-0.014850772,1.090017585,3.014519779,-4.277052489,-4.38802327,-4.582082993,-4.833239021,-2.723001907,-4.858915253,-4.782911362,-3.160726838 -3122,L188H,0.058826245,-0.055225608,-0.017755379,-1.662675485,-2.357136858,-0.098123852,0.057282176,0.060370314,-0.044102068,-0.026969915,-0.0834813,-0.005758247,-0.029752511,-1.643723491,-1.681627479,-2.160818746,-2.553454969,0.963682736,0.712865124,-11.74983114,-10.83752493,-11.60532037,-13.25999049,-10.7775797,-12.26874023,-8.058000501,-6.605246233 -3123,L188K,-0.001801911,-0.644136855,-1.716633939,-2.274492774,-2.552699689,-0.140854673,-0.064246204,0.060642383,-0.096054253,-0.699078132,-0.589195578,-2.046708091,-1.386559787,-2.36360449,-2.185381057,-2.40357849,-2.701820888,1.608030166,-0.087844622,-12.45666786,-12.91355421,-12.84788934,-13.00431638,-10.77449552,-12.74308385,-9.916627407,-10.2655079 -3124,L188M,0.030134035,0.037080838,0.02556723,0.031242474,0.013036622,0.173557643,0.028108513,0.032159556,-0.011581777,0.065467926,0.008693749,0.017676482,0.033457978,0.01589654,0.046588408,0.017735036,0.008338207,1.212035903,2.698347019,-3.839198486,-3.504306038,-3.545502739,-4.986957878,-3.594585266,-3.564640511,-3.579982452,-2.04499402 -3125,L188N,0.076311861,0.079064491,-0.519759545,-1.792225273,-2.220947187,-0.29053747,0.050030263,0.102593459,-0.071102186,0.174533065,-0.016404084,-0.51779139,-0.521727699,-1.948631142,-1.635819404,-1.988605142,-2.453289231,3.426463347,2.190753952,-11.74352516,-12.58189905,-11.66700979,-12.91844707,-10.62159679,-10.92867307,-7.983485018,-6.731979184 -3126,L188Q,0.002275617,-0.058223163,-0.323303452,-1.776922785,-2.796089769,-0.156741203,0.001982734,0.002568499,0.054664137,-0.065741817,-0.050704508,-0.332602614,-0.31400429,-1.94112154,-1.61272403,-2.82619358,-2.765985958,1.409330674,0.716480244,-11.87106411,-12.56353465,-12.18360018,-12.22432749,-10.23496996,-12.14888824,-9.871206654,-9.953681979 -3127,L188P,-0.008176472,-1.330026782,-2.184384119,-2.504880619,-2.85520948,-0.068645738,-0.033965316,0.017612372,0.063524615,-1.586828252,-1.073225311,-2.159686701,-2.209081536,-2.318975247,-2.69078599,-2.679284398,-3.031134562,-0.53150622,-1.018168713,-11.32190251,-11.66167559,-11.90596698,-12.19796056,-9.865851921,-10.97805747,-9.16732865,-8.426016059 -3128,L188S,0.030988929,-0.054324574,-0.048228196,-0.200926457,-1.805171884,-0.162694057,0.00800728,0.053970577,0.01969241,-0.068205367,-0.040443781,-0.068000806,-0.028455585,-0.235134884,-0.16671803,-1.803739959,-1.806603809,1.253373888,1.34711866,-10.08657208,-10.71719389,-10.30387226,-11.6769986,-8.596399765,-9.138395905,-7.354691946,-5.144556167 -3129,L188R,-0.006223496,-1.365831231,-2.174752305,-2.536338651,-2.954465915,-0.093969237,-0.030050752,0.01760376,0.054898559,-1.595067779,-1.136594683,-2.227598233,-2.121906377,-2.322645882,-2.75003142,-2.760559891,-3.148371939,-0.68783752,-1.025059173,-12.20531454,-12.96899566,-12.20203719,-12.636119,-10.76133637,-12.45808447,-9.916627407,-10.2655079 -3130,L188T,0.035537495,-0.034539709,-0.031612913,-0.033241597,-0.298301891,-0.048583855,0.046285312,0.024789677,0.034205156,-0.025537945,-0.043541473,-0.042607992,-0.020617833,-0.059374488,-0.007108706,-0.267847774,-0.328756008,1.459902563,2.069588987,-8.715158913,-8.939680237,-9.228401093,-9.245671318,-6.994047455,-9.167994461,-6.558231144,-4.640139284 -3131,L188W,-0.005505666,0.001083717,0.021869237,-1.238161009,-1.912952574,-0.106983638,-0.03930288,0.028291549,0.037691244,0.008379983,-0.00621255,0.017946902,0.025791571,-1.008889635,-1.467432382,-1.983362087,-1.842543061,2.25388802,1.567719347,-8.049796152,-7.617623573,-7.997799614,-9.967349876,-6.905369385,-7.76083831,-6.204658488,-4.490488647 -3132,L188V,0.021504185,-0.025040412,-0.046188727,-0.030946418,-0.081581387,-0.063368251,-0.025193864,0.068202234,0.007415074,-0.0465887,-0.003492123,-0.073721825,-0.018655629,-0.098037803,0.036144968,-0.102397304,-0.060765469,1.361759848,2.235593191,-5.332364012,-5.543175827,-5.140654068,-5.789023201,-4.268513283,-5.920453682,-5.755182501,-2.917990092 -3133,L188Y,-0.058809656,0.013988469,0.016992074,-0.024781799,-1.120273917,-0.046393262,-0.112965698,-0.004653613,0.176668238,-0.01717766,0.045154598,0.052512005,-0.018527857,-0.050088782,0.000525184,-0.824748339,-1.415799494,0.766689025,1.387112338,-9.338633989,-8.737391167,-7.995724747,-11.57245286,-8.770836037,-9.616765137,-4.969438372,-2.29874559 -3134,R189A,0.022913215,-0.019845914,0.014606148,-0.020606068,-0.017229056,-0.051370195,0.010717579,0.03510885,0.028612884,-0.029198183,-0.010493644,0.032562334,-0.003350039,-0.033521329,-0.007690806,-0.009867948,-0.024590163,1.323844396,2.642309041,-3.931520349,-4.95875351,-3.029088089,-3.723505119,-3.328450974,-4.617804054,-4.923875324,-0.415841034 -3135,R189C,0.078814877,0.001594152,0.020839035,0.012955114,-0.003296714,-0.096298044,0.090781446,0.066848308,0.020112668,-0.027823237,0.031011541,0.013553262,0.028124808,-0.017634155,0.043544383,-0.000220234,-0.006373194,1.169124768,2.573707615,-8.228251373,-9.019602577,-8.184463356,-6.797397552,-9.041738205,-8.098055176,-7.501274445,-4.73699917 -3136,R189E,-0.007379596,0.000276437,-0.000922904,0.004874544,-0.303910933,-0.078782972,-0.014978659,0.000219467,0.076141275,-0.026325822,0.026878696,-0.012173231,0.010327423,0.017952239,-0.008203152,-0.247869118,-0.359952747,1.16112586,1.860840972,-2.318811018,-2.49918364,-2.254430847,-1.320054329,-3.560546631,-1.959839645,-3.706258794,-0.219645669 -3137,R189D,-0.011796437,-0.056782793,-0.040873402,-0.039571741,-1.147991783,-0.134423248,-0.046501191,0.022908317,0.022928388,-0.071921271,-0.041644314,-0.023698278,-0.058048526,-0.082231114,0.003087633,-0.786578036,-1.509405529,1.021315688,1.452288201,-3.589498279,-3.22622287,-3.528517273,-2.489105301,-4.577162003,-4.126483948,-4.436365668,-1.875344046 -3138,R189G,0.027454466,-0.011249161,0.005039355,-0.003235169,-0.047906629,-0.083224907,0.017991669,0.036917262,0.029327327,-0.035870207,0.013371886,0.019596231,-0.009517522,-0.019499417,0.01302908,-0.052334861,-0.043478397,1.347927753,2.52259184,-3.647680479,-4.445239037,-2.129972816,-4.136704422,-4.171114182,-3.355371941,-4.096019413,-1.668978148 -3139,R189F,0.057231551,0.034031176,0.068291801,0.028687159,0.034164252,-0.094308002,0.030692161,0.083770941,0.042186858,-0.000672149,0.068734501,0.095155673,0.041427928,0.084024346,-0.026650029,0.04400315,0.024325354,1.107605496,2.785883252,-8.780333279,-10.46347237,-8.304324829,-6.398182083,-8.002809303,-10.73287782,-7.379134872,-4.604622404 -3140,R189I,-0.012396398,-0.001648858,-0.0369291,-0.001477996,-1.078739255,-0.083964217,-0.037666794,0.012873998,0.006706456,-0.034132711,0.030834995,-0.010018581,-0.063839619,-0.013159239,0.010203248,-0.852819229,-1.30465928,0.630413013,1.369631712,-8.738645613,-10.87568135,-8.50214534,-7.223305679,-8.093512413,-8.998583282,-7.171284253,-3.275832991 -3141,R189H,0.062862684,0.00376831,0.022097897,-0.00076256,0.028994949,-0.089242473,0.052394487,0.07333088,0.062336131,0.004993428,0.002543191,0.02891534,0.015280453,-0.012053987,0.010528867,0.018319629,0.039670268,1.189076917,2.640709113,-1.28419646,-1.107344467,-1.593092239,-1.12446067,-0.683609589,-1.912475334,-2.536985322,-1.992054078 -3142,R189K,-0.014139725,-0.095491851,0.056788633,0.047192499,0.043095827,-0.038630584,-0.040698343,0.012418894,-0.010063755,-0.041819539,-0.149164163,0.165698448,-0.052121183,0.068810425,0.025574573,0.130410561,-0.044218907,1.107384667,2.930494234,-3.028105875,-3.971506363,-3.045740662,-2.451450752,-2.803053795,-2.868777802,-4.513367825,-0.745441358 -3143,R189M,0.025213489,-0.035412455,-0.008399852,-0.01574027,0.023547909,0.010953735,0.003277383,0.047149595,0.103210938,-0.066014348,-0.004810562,0.027653874,-0.044453577,0.031946647,-0.063427187,0.08429917,-0.037203352,1.083498741,2.851156773,-8.903250528,-10.10188995,-8.435840111,-7.52246656,-9.086401131,-9.369654884,-6.560797542,-4.072348864 -3144,R189L,0.039392461,-0.020381434,0.004636895,-0.013295572,-0.020162666,-0.115935554,0.013405624,0.065379298,0.054046329,-0.028537327,-0.01222554,0.009692174,-0.000418384,-0.035993594,0.009402451,-0.004823205,-0.035502126,0.978053416,2.399313709,-8.010846902,-9.612922928,-7.479939247,-6.44412664,-8.485814766,-8.031430931,-6.018101881,-2.595972823 -3145,R189N,0.047490996,-0.023471844,0.025487403,-0.110464545,-0.151627343,-0.074115839,0.033495698,0.061486293,0.129708639,-0.015007196,-0.031936491,0.056528202,-0.005553397,-0.060123303,-0.160805786,-0.211230015,-0.09202467,1.381560703,2.056764385,-3.279822583,-3.146155586,-4.47727977,-2.493766563,-2.560272842,-3.721638153,-4.196688943,-2.085489161 -3146,R189Q,-0.007294685,-0.008469168,0.016089434,0.006403879,-0.002750312,0.045376077,-0.013983229,-0.00060614,0.1833259,0.104433312,-0.121371648,0.104409615,-0.072230748,0.090523707,-0.07771595,0.035566676,-0.041067299,1.543610422,3.106887046,-1.239628874,-1.661118706,-1.191769196,-0.303437935,-1.711987938,-1.329830597,-2.834561775,-0.505662056 -3147,R189P,0.025602858,-0.026666004,-0.694758416,-1.840275487,-2.171437555,-0.078551041,0.022659278,0.028546437,0.03696397,-0.044147067,-0.00918494,-0.630869773,-0.758647059,-1.910986189,-1.769564785,-2.186467985,-2.156407125,3.080772019,1.80421002,-10.1447918,-10.98275433,-9.73491716,-9.564907532,-10.23873639,-10.20264357,-9.362421619,-8.092063116 -3148,R189S,0.025602035,-0.037027944,-0.011408995,-0.029251264,-0.039930577,-0.079979839,0.020008244,0.031195825,0.046147889,-0.053011097,-0.02104479,-0.026802954,0.003984964,-0.070728498,0.01222597,-0.023401961,-0.056459193,1.372052346,2.555496231,-4.382848163,-5.352790283,-3.619765419,-4.23592218,-3.896212509,-4.809550423,-4.770054274,-1.618413918 -3149,R189T,0.024339399,-0.014084962,-0.031068516,-0.015227365,-0.145861113,-0.092432266,0.016677793,0.032001004,0.029558104,-0.020310003,-0.007859921,-0.033220341,-0.028916691,-0.051340929,0.0208862,-0.147006084,-0.144716141,1.446717983,2.240818722,-5.305592595,-6.894766083,-4.877355072,-4.841380341,-4.899679291,-5.014782188,-4.884648673,-1.586938534 -3150,R189W,0.027951349,-0.048304976,0.021896105,-0.004475476,0.037155394,-0.033956169,0.03102118,0.024881517,0.101263733,-0.081443202,-0.01516675,0.052842872,-0.009050662,-0.067326212,0.05837526,-0.015034084,0.089344871,1.160699455,2.310883681,-8.983569702,-9.129856041,-10.24698942,-7.15780481,-8.672057785,-9.711140457,-7.534908913,-5.4617896 -3151,R189V,0.017249786,-0.004532015,-0.021470896,-0.020956172,-0.162167656,-0.097538691,-0.000909202,0.035408774,0.097371881,-0.031276592,0.022212562,-0.024458642,-0.018483149,-0.060147937,0.018235593,-0.1562732,-0.168062112,1.338312844,2.131367392,-7.680897583,-9.525529778,-7.750949768,-6.551226051,-7.29980954,-7.276972778,-7.286696524,-2.304073754 -3152,R189Y,-0.005833714,-0.040701081,-0.066502364,-0.058099121,-0.009767181,-0.080644685,-0.002289672,-0.009377756,-0.090665426,-0.105438385,0.024036224,-0.090912408,-0.042092319,-0.089733841,-0.0264644,-0.025884033,0.006349672,1.311321958,2.476381603,-5.440068082,-5.60817038,-5.616003227,-3.742688858,-4.940997696,-7.292480248,-5.050421843,-2.842339122 -3153,K190A,0.051136055,0.018567251,0.046552289,0.114627695,0.131802291,-0.079719324,0.075854083,0.026418026,0.165095875,0.041679545,-0.004545044,0.071827673,0.021276905,0.169760503,0.059494887,0.248097525,0.015507056,0.999647928,3.124259304,-2.626431894,-1.599060783,-3.377694336,-3.392615669,-2.597986038,-2.164802643,-2.877926169,0.052349634 -3154,K190C,0.070959461,0.016238781,0.021940961,0.089098448,0.090686242,-0.116190815,0.043757902,0.098161019,0.107603174,0.027743767,0.004733794,0.026721788,0.017160134,0.162300391,0.015896504,0.207180058,-0.025807575,0.957748142,2.90986283,-7.221659456,-6.842708954,-7.566843178,-7.711919304,-7.469255188,-6.517570656,-6.985270253,-4.819136913 -3155,K190E,0.058327508,0.037203693,0.027473486,0.138486931,0.154985174,-0.021730812,0.050453478,0.066201538,0.020038849,0.072504025,0.00190336,0.035176847,0.019770124,0.20378294,0.073190921,0.286309218,0.023661129,1.193443681,3.2232906,-2.66321443,-2.384031586,-3.417803093,-3.306620918,-2.100569275,-2.107047279,-3.30078447,-1.676094159 -3156,K190D,0.029619665,0.018094706,0.002788744,0.084752212,0.100962865,-0.030071496,0.090071967,-0.030832637,0.084320886,0.022055194,0.014134218,-0.003960665,0.009538152,0.073222895,0.096281528,0.158894933,0.043030797,1.075612453,3.070360491,-4.047834096,-3.358297592,-4.196962395,-4.632644722,-4.360793472,-3.690472298,-4.55623057,-2.611198743 -3157,K190G,0.083653955,0.003621818,0.012560167,0.115267979,0.077161286,-0.061159062,0.080157845,0.087150064,0.119284101,0.003926541,0.003317094,0.008079678,0.017040656,0.14099088,0.089545078,0.157088787,-0.002766216,1.234188512,3.071937563,-3.954357947,-3.668315971,-3.387813438,-5.207447662,-4.053275703,-3.454936958,-4.17547608,-1.854062425 -3158,K190F,0.026829027,-0.12065612,-0.051680839,0.022996748,-0.217008299,-0.082375449,0.069052101,-0.015394047,0.303822896,-0.156337366,-0.084974873,-0.015602527,-0.08775915,0.078721355,-0.032727859,-0.040411595,-0.393605002,1.270488892,2.533330658,-7.097180214,-7.271371613,-6.931698273,-8.425394798,-7.124956749,-5.732479637,-6.209571041,-4.184823022 -3159,K190I,0.082828013,0.02723384,-0.018771113,0.122197355,0.108124379,-0.100185007,0.094393409,0.071262617,-0.062147907,0.060944062,-0.006476382,0.003791827,-0.041334053,0.207848848,0.036545862,0.200889968,0.01535879,0.967372558,3.056630347,-5.944695491,-5.871439789,-6.525079903,-6.842501671,-5.422847198,-5.061608894,-5.772740853,-2.567488527 -3160,K190H,0.049684448,0.017389238,0.003817184,0.073260169,0.113907221,-0.034282122,0.086644147,0.012724749,0.126908329,-0.024579186,0.059357661,-0.020588703,0.028223071,0.109778631,0.036741707,0.124099779,0.103714662,1.134830888,2.999257431,-2.976281262,-3.352399399,-3.63552626,-3.501289604,-2.967187119,-1.425003929,-4.103015946,-2.385403038 -3161,K190M,0.08332503,-0.006246637,-0.035846314,0.044839563,0.06426857,-0.050357398,0.101536085,0.065113974,-0.075112884,-0.044110595,0.031617321,-0.101677481,0.029984853,0.051754217,0.037924908,0.079340564,0.049196575,1.057834437,2.853788227,-5.124878133,-5.275131081,-5.129668716,-6.207947479,-4.888170845,-4.123472542,-4.722812889,-1.617101485 -3162,K190L,0.062068256,0.036144497,0.0337272,0.110483771,0.09924628,-0.121457433,0.082031517,0.042104994,0.108941825,0.024758913,0.04753008,0.039286632,0.028167768,0.162424627,0.058542914,0.168380517,0.030112042,1.08321687,3.161940692,-4.357624245,-4.189187859,-4.041275627,-5.749778305,-4.630841866,-3.177037567,-4.785073097,-0.804850742 -3163,K190N,0.077588054,-0.007869114,-0.021035625,0.171261414,0.116235187,-0.078748344,0.095884348,0.059291759,0.034762106,0.020319749,-0.036057976,-0.023380445,-0.018690804,0.175079759,0.167443068,0.140003345,0.092467028,1.098635386,3.12187274,-1.255120435,-1.722629776,-1.229730743,-1.207325806,-0.798408813,-1.317507034,-2.432203271,-2.219738678 -3164,K190Q,-0.033031008,0.023736288,0.02468798,0.161308207,0.17701405,-0.050846062,-0.05854237,-0.007519645,0.092224103,0.085106939,-0.037634364,0.12610642,-0.07673046,0.269238161,0.053378252,0.288040144,0.065987956,1.33142065,3.565361933,-1.656487144,-1.828385056,-2.233658081,-1.897497978,-1.060336876,-1.262557732,-1.82075844,-1.449972561 -3165,K190P,0.048758321,0.027105125,-0.030132237,-1.54116656,-2.16444907,-0.094600102,0.07719275,0.020323891,0.138727575,-0.006179954,0.060390204,-0.057393027,-0.002871446,-1.457132799,-1.62520032,-2.112064997,-2.216833143,0.829209801,0.717584806,-9.035988582,-8.657854446,-9.435519875,-9.506569382,-9.162935905,-8.417063301,-8.816291035,-8.695880952 -3166,K190S,0.052101356,0.012444461,0.017023187,0.088159332,0.101368661,-0.091847862,0.05254718,0.051655532,0.159105511,-0.005563883,0.030452805,-0.008870551,0.042916924,0.094306568,0.082012095,0.146532306,0.056205016,1.055509506,2.96653421,-3.193422433,-2.949397385,-3.739954025,-3.81310479,-3.00731398,-2.457341988,-3.602818258,-1.930497076 -3167,K190R,0.059388287,0.034166915,0.027263828,0.121003326,0.134726194,-0.026695691,0.085517604,0.033258969,0.112030158,0.026808794,0.041525036,0.046364432,0.008163223,0.142171569,0.099835083,0.209778827,0.059673561,1.024261699,3.167294461,-1.339058783,-1.237130653,-1.498608902,-1.706366058,-1.629141991,-0.62404631,-2.512149002,-0.134337415 -3168,K190T,0.031442154,0.019029975,0.002920681,0.092490761,0.142137028,-0.121792833,0.025171078,0.03771323,0.162248032,0.017023252,0.021036698,0.00745841,-0.001617048,0.150109471,0.03487205,0.237646215,0.046627841,1.160203223,3.253758487,-1.976977867,-1.508473595,-2.504234955,-2.388802971,-1.477085678,-2.006292137,-3.063114498,-1.452826613 -3169,K190W,0.06670215,0.0000206,-0.013984795,0.089247088,-0.205482836,-0.068286923,0.090452611,0.042951688,0.09058856,-0.002043236,0.002084397,-0.050690436,0.022720846,0.107116412,0.071377764,-0.083540765,-0.327424906,1.155297011,2.294729223,-6.899035202,-7.153238167,-6.930895485,-7.452406792,-7.105028824,-5.853606743,-6.824246284,-3.986297685 -3170,K190V,0.110414599,0.027055392,0.029952699,0.110701423,0.094288889,-0.087925831,0.099816793,0.121012405,0.170951619,0.015919797,0.038190986,0.011041583,0.048863815,0.151427513,0.069975333,0.172975308,0.01560247,1.016875373,2.950497949,-5.661271236,-5.219789673,-6.221462189,-6.379913826,-5.394115349,-5.091075142,-5.171961043,-2.85580433 -3171,K190Y,0.035999566,0.067232282,0.047060162,0.083534659,0.110729703,-0.026863688,0.051406285,0.020592847,0.261262869,0.090837581,0.043626982,0.131171136,-0.037050813,0.125649867,0.04141945,0.215373681,0.006085725,0.962428117,3.017088674,-5.767462352,-5.644081009,-6.642833618,-6.668387169,-6.034222748,-3.847787216,-5.165993341,-3.422026801 -3172,L191A,-0.059776188,0.005842156,0.00585183,-0.073817836,-1.740208362,-0.032925196,-0.033920126,-0.08563225,-0.021483526,0.025795575,-0.014111263,0.047756335,-0.036052675,-0.047840545,-0.099795126,-1.70812149,-1.772295234,0.666048346,1.31034536,-5.839957387,-6.999184265,-5.000927307,-4.159628098,-7.287010048,-5.753037216,-5.88403837,-3.532099293 -3173,L191C,0.018012068,0.064766801,0.053803178,0.040816542,-1.540306586,-0.024951217,0.081573971,-0.045549836,0.084121055,0.046687225,0.082846377,0.030213795,0.07739256,0.014999944,0.066633139,-1.199666891,-1.880946281,0.683367661,1.336175506,-8.519051564,-9.012254379,-7.562880447,-8.25594664,-9.109028976,-8.655147377,-7.982534082,-6.1619902 -3174,L191E,-0.043555289,-0.01730507,-0.612504427,-1.902824222,-3.091910494,-0.053865534,-0.052802555,-0.034308022,-0.028454746,-0.039201473,0.004591334,-0.469107389,-0.755901465,-1.80467654,-2.000971903,-2.956461774,-3.227359214,1.65663859,0.799096426,-10.67940588,-11.12017895,-9.824424095,-9.851792038,-12.21956138,-10.38107295,-10.35567423,-10.06195992 -3175,L191D,-0.038911075,-0.732807909,-1.933339784,-1.881349089,-2.706935997,-0.003184472,-0.016557444,-0.061264705,0.107605926,-0.732893411,-0.732722406,-2.144666753,-1.722012814,-1.49458493,-2.268113248,-2.521431427,-2.892440567,3.739067577,1.768312328,-10.82870968,-11.1525738,-10.25715211,-10.19130738,-11.79012745,-10.75238766,-10.35567423,-10.06195978 -3176,L191G,-0.017561478,-0.029738274,-1.184604464,-2.059512668,-2.8190959,-0.058443017,-0.020674798,-0.014448157,0.012760616,-0.02402161,-0.035454937,-1.29368819,-1.075520737,-2.140236863,-1.978788473,-2.667099222,-2.971092577,0.689531227,0.09432728,-10.57089603,-11.39756277,-9.565598671,-9.668758163,-11.86182362,-10.36073695,-10.35567423,-10.06195812 -3177,L191F,-0.043325476,-0.064916196,-0.004016675,-0.018522592,-0.063981014,-0.058554393,-0.09235262,0.005701668,-0.053447004,-0.114845314,-0.014987078,-0.022174274,0.014140925,-0.016566351,-0.020478832,-0.106827017,-0.021135011,1.246280512,2.180128282,-5.103042503,-5.235241013,-4.748483673,-5.931625809,-5.02568882,-4.574173203,-5.222541644,-1.549945493 -3178,L191I,0.062241091,-0.033821056,0.030783902,0.026537918,-0.075122951,0.05837182,0.062147674,0.062334508,-0.044021891,-0.128856029,0.061213917,-0.016329038,0.077896842,-0.021593858,0.074669693,-0.087826664,-0.062419237,1.371026103,2.356899824,-3.208454457,-2.789797478,-2.946127701,-2.613525307,-3.739199188,-3.953622612,-4.308825097,-0.724836335 -3179,L191H,-0.05895876,-0.05676943,-0.032335669,-1.225496,-2.35386511,-0.042467661,-0.04998487,-0.067932649,0.011748596,-0.065858853,-0.047680006,0.012794526,-0.077465864,-1.006870602,-1.444121397,-2.303489401,-2.404240818,1.998396659,1.339675274,-11.17417525,-11.32139128,-10.1391218,-11.01269725,-12.23473479,-11.16293111,-10.15137662,-9.151812278 -3180,L191K,0.034661124,-0.210727357,-1.324963709,-2.368774727,-2.566725383,-0.011719909,0.029421245,0.039901003,-0.061680321,-0.299710498,-0.121744215,-1.40167992,-1.248247498,-2.103780615,-2.633768839,-2.477414598,-2.656036167,2.912919216,1.266880981,-10.47715518,-10.96264593,-9.726199883,-9.895066139,-11.21703923,-10.5848247,-10.35567423,-10.06195785 -3181,L191M,0.046768924,-0.003572198,0.041040194,0.073594284,0.010860929,0.052049754,0.005454089,0.088083758,0.04639667,-0.067989733,0.060845337,-0.002641821,0.084722209,0.019781593,0.127406974,-0.001669872,0.02339173,1.306832352,2.660187788,-4.574158328,-5.096770012,-3.992778328,-4.996237892,-5.238987679,-3.546017731,-5.604151706,-2.896431214 -3182,L191N,-0.016918433,-0.000398916,-0.460316797,-1.793718647,-2.564733321,-0.049028709,-0.028787383,-0.005049482,-0.005281826,-0.047898525,0.047100694,-0.392725077,-0.527908517,-1.541983803,-2.045453491,-2.459685831,-2.66978081,1.748137847,0.9113451,-10.54702189,-10.84608856,-9.396377975,-10.31425221,-11.77760453,-10.40078619,-10.35567423,-10.06196007 -3183,L191Q,-0.040736725,-0.025382305,-0.031031258,-1.20523162,-2.104050617,-0.025114123,-0.044604074,-0.036869375,-0.010878397,-0.046066829,-0.004697781,-0.048641649,-0.013420866,-1.114183375,-1.296279865,-2.830240039,-1.377861194,0.767103489,0.743571631,-8.919233948,-9.653577683,-7.878621773,-8.363665382,-9.763488113,-8.936816788,-8.91511272,-6.890620775 -3184,L191P,-0.025812619,-1.076675827,-2.06903566,-2.227364915,-2.918265711,-0.040128255,-0.009972771,-0.041652467,0.07170044,-1.203099562,-0.950252091,-2.147511487,-1.990559832,-2.262615937,-2.192113892,-2.787517595,-3.049013826,0.262499949,-0.729954921,-10.66117895,-11.29977943,-10.10428368,-9.779856575,-11.6346221,-10.48735298,-10.33976853,-9.987470731 -3185,L191S,-0.016333601,-0.01827237,0.010130785,-1.662707776,-2.314900941,-0.067036207,-0.005211839,-0.027455362,0.005748683,-0.048884438,0.012339699,0.031340243,-0.011078674,-1.675877383,-1.649538169,-2.48087513,-2.148926751,0.588944459,0.685853919,-8.272700656,-9.025064835,-7.5166185,-7.289787987,-9.716501274,-7.815530685,-8.297106203,-5.796244727 -3186,L191R,-0.032735981,-1.127532557,-2.153819295,-2.280193673,-2.845487107,-0.033077311,-0.013476613,-0.051995348,0.053713819,-1.26097335,-0.994091763,-2.054599881,-2.253038708,-2.099123257,-2.461264089,-2.773787235,-2.917186978,0.121637977,-0.759073797,-10.62409386,-10.94906579,-9.847023048,-10.09692328,-11.19254352,-11.03491365,-10.33780824,-9.942447565 -3187,L191T,0.024844332,0.005427876,0.014034733,-0.042890211,-1.584024862,-0.03320954,0.04248524,0.007203423,-0.010171907,-0.057203746,0.068059497,-0.016246637,0.044316102,-0.09322763,0.007447208,-1.662351264,-1.505698459,0.876167761,1.323265973,-6.647715549,-6.820422272,-6.73479493,-4.781570465,-8.226654114,-6.675135963,-6.911223132,-4.560065386 -3188,L191W,-0.017274081,0.015300961,0.03019861,-0.220608884,-1.752099142,0.242347978,-0.010026577,-0.024521585,-0.181851106,-0.066270215,0.096872137,-0.023723085,0.084120305,-0.276193423,-0.165024344,-1.716296687,-1.787901597,1.385996687,1.378507776,-9.900976346,-9.978946297,-9.373570457,-9.707945427,-10.2954249,-10.14899465,-9.144344099,-7.448499955 -3189,L191V,-0.038041103,0.019414397,0.01213088,0.042499229,-0.313009326,0.001180688,-0.064818154,-0.011264051,-0.012127709,0.04407792,-0.005249126,0.076282177,-0.052020417,0.081059318,0.00393914,-0.210515925,-0.415502727,1.139131189,1.913296832,-4.36171153,-4.713060577,-4.103531609,-2.94987989,-5.03966436,-5.002421211,-5.043673885,-1.640404854 -3190,L191Y,0.0039196,0.009608831,-0.013623645,-0.011806982,-1.555942535,-0.046269527,-0.010525862,0.018365061,0.027798256,0.005545795,0.013671866,0.010500528,-0.037747817,-0.031055986,0.007442022,-1.418293146,-1.693591924,0.675699114,1.321324272,-7.892167682,-8.037979385,-7.679999176,-8.026649223,-8.446566978,-7.269643646,-6.896882594,-2.739769986 -3191,L192A,-0.030093041,-0.018597648,0.004566675,-0.032185099,-1.556554077,0.00413323,-0.015503579,-0.044682502,0.003284755,-0.043783456,0.00658816,0.008439791,0.000693559,-0.041853207,-0.02251699,-1.447693105,-1.665415049,0.66379259,1.319291736,-4.72954753,-4.137270439,-3.572457054,-6.561465111,-5.062589958,-4.313955086,-4.777098457,-0.202280221 -3192,L192C,-0.072189961,-0.06074313,-0.017870328,-0.061819434,-1.063779785,-0.009946776,-0.053528125,-0.090851796,0.003168649,-0.002721536,-0.118764723,-0.049487579,0.013746924,-0.072777275,-0.050861593,-0.728730691,-1.398828879,1.134913898,1.514565605,-7.789434381,-6.730953293,-6.716847015,-9.172089432,-7.562688057,-8.764594109,-7.11180867,-3.959151756 -3193,L192E,-0.016312019,-0.005492534,-1.192431906,-2.261885403,-2.829024756,-0.14821705,-0.023575416,-0.009048622,-0.059880141,-0.022731462,0.011746394,-1.292486789,-1.092377023,-1.980997907,-2.542772899,-2.945806655,-2.712242856,2.461896616,1.000907241,-9.666221663,-8.421228149,-9.187280212,-9.836956131,-10.0482147,-10.83742912,-7.739932646,-2.360981195 -3194,L192D,-0.0977562,-0.746521816,-1.929971182,-2.302637077,-2.832883323,0.024337091,-0.073482813,-0.122029587,0.013568469,-0.71316072,-0.779882911,-1.835068031,-2.024874332,-1.995305372,-2.609968782,-2.534145388,-3.131621257,3.166304976,1.248856796,-10.32483852,-8.985172951,-10.55701305,-11.21356181,-9.843146423,-11.02529835,-7.084283971,-1.936932588 -3195,L192G,-0.02054542,-0.018021734,-0.269382432,-1.97212395,-2.784570413,-0.048436697,0.00196303,-0.043053869,0.025664535,-0.033830449,-0.002213019,-0.220885761,-0.317879102,-2.032767763,-1.911480136,-2.884536999,-2.684603827,1.160947692,0.672098558,-8.995588751,-8.422604248,-7.772801163,-9.96720742,-8.737161385,-10.07816954,-6.544715929,-2.866100671 -3196,L192F,0.018059132,0.013732505,0.081264467,0.052959093,-0.042845814,0.008473507,-0.035597165,0.071715429,-0.081348484,0.02380942,0.003655589,0.120460733,0.042068201,0.054372465,0.051545721,-0.025444519,-0.060247109,1.176585771,2.544189688,-4.061002045,-3.990355667,-3.315355515,-4.827034035,-3.990668472,-4.181596535,-5.177439804,-1.89699271 -3197,L192I,-0.069777974,-0.001081698,0.027459208,-0.077981889,-0.063610451,0.090775706,-0.024977776,-0.114578172,-0.027931268,0.009687722,-0.011851118,0.071050254,-0.016131839,-0.05060818,-0.105355598,-0.042905533,-0.084315368,1.293262937,2.444541636,-3.254030234,-2.763771927,-3.42018129,-3.976919296,-2.791678116,-3.31760054,-4.181987799,-2.110439195 -3198,L192H,0.002827638,-0.021074957,0.018251937,-1.081000003,-1.791421007,-0.068898464,0.030313309,-0.024658034,0.029338594,-0.037038927,-0.005110986,0.016572451,0.019931422,-1.017581766,-1.14441824,-1.880932874,-1.70190914,2.482627962,1.777334189,-9.941204733,-9.223816299,-9.009222076,-9.995435608,-9.023766274,-12.45378341,-6.254815287,-1.906427831 -3199,L192K,-0.011885219,-0.082585491,-1.293341385,-2.342098539,-2.784299155,-0.01344116,0.052918327,-0.076688764,-0.006815572,-0.054553174,-0.110617808,-1.244646347,-1.342036422,-2.279944951,-2.404252127,-2.642693709,-2.925904601,0.69323654,0.082934906,-10.83902905,-8.775747437,-11.56617721,-10.44357752,-9.262011498,-14.14763158,-7.387362891,-2.888252352 -3200,L192M,0.020424973,-0.035529635,0.050145005,0.012442773,-0.01111662,-0.076911852,0.039294164,0.001555781,0.000208212,-0.016899802,-0.054159468,0.110139794,-0.009849785,0.015649866,0.00923568,-0.002237326,-0.019995913,1.190825765,2.626185943,-4.326503384,-3.801950821,-3.993620064,-4.860037186,-4.138020561,-4.83888829,-5.642897883,-3.136287209 -3201,L192N,-0.066510789,-0.068928879,-0.53117053,-1.98860017,-2.853349806,-0.08928135,-0.049294769,-0.083726809,0.042282662,-0.102189123,-0.035668635,-0.51817757,-0.54416349,-1.875695468,-2.101504871,-2.715565481,-2.991134131,1.739102434,0.796762298,-10.15522688,-8.819087143,-8.484116142,-11.26751642,-9.557899368,-12.64751531,-7.595864006,-2.240495693 -3202,L192Q,-0.035816492,-0.030334247,-0.008216564,-1.556737045,-1.901721304,-0.072253507,-0.037717294,-0.033915689,-0.030206312,-0.065742397,0.005073904,-0.029419805,0.012986677,-1.306928441,-1.806545649,-2.000670417,-1.80277219,2.310706123,1.519088042,-8.99955246,-8.512910271,-8.233344154,-9.799404083,-8.140600395,-10.3115034,-6.495590624,-2.372581541 -3203,L192P,-0.076151972,-1.194151849,-2.355943961,-2.675004871,-2.830189854,-0.055266875,-0.049833821,-0.102470122,0.073053756,-1.329194622,-1.059109075,-2.320333653,-2.391554269,-2.577481006,-2.772528735,-2.940229764,-2.720149943,-0.177793423,-0.829006213,-11.16924901,-10.16042255,-10.51537383,-12.06715256,-11.27947244,-11.82382368,-9.693537361,-6.301965177 -3204,L192S,-0.052541483,-0.007488388,-0.024562893,-0.868309501,-2.098896634,-0.061763032,-0.020935118,-0.084147848,0.018634248,-0.008444171,-0.006532605,-0.033722657,-0.015403129,-0.645945248,-1.090673754,-1.888023554,-2.309769713,1.880949767,1.466201925,-7.370516104,-6.953204765,-5.970887466,-8.942981926,-7.358421989,-7.627084373,-6.249580821,-2.322293918 -3205,L192R,-0.069107056,-0.61776422,-2.09799211,-2.295990668,-3.061556477,-0.024888612,-0.037694169,-0.100519942,0.062532852,-0.631930701,-0.603597739,-2.166418547,-2.029565673,-2.069091586,-2.522889749,-2.710593944,-3.41251901,0.621005751,-0.48666955,-9.847440504,-8.514317322,-8.736329132,-10.07694566,-8.260961823,-13.64864859,-7.016678992,-1.925754707 -3206,L192T,-0.042714469,0.029272092,0.051726372,0.001721529,-0.833308562,0.039246727,-0.020944903,-0.064484034,-0.014532755,0.045462563,0.01308162,0.097253698,0.006199046,0.02872325,-0.025280193,-0.565771477,-1.100845647,0.572736437,1.394288648,-4.708355646,-4.498802757,-3.636230042,-5.809624222,-5.306235611,-4.290885597,-4.083399229,-1.048326915 -3207,L192W,-0.015367999,-0.040580889,-0.023038294,-0.037028146,-0.944648318,-0.06831121,-0.026788362,-0.003947635,0.014168919,-0.061084042,-0.020077736,-0.032498512,-0.013578075,-0.067797115,-0.006259176,-0.737824818,-1.151471818,1.096908765,1.496590095,-8.171825443,-8.033199554,-7.596383865,-9.367173676,-8.492406487,-7.369963631,-6.534484337,-0.637565123 -3208,L192V,-0.031325134,0.001978786,0.008643689,-0.048912497,-0.100550592,0.079464661,-0.0158382,-0.046812068,-0.071795844,-0.043648561,0.047606133,-0.007948019,0.025235396,-0.071658636,-0.026166357,-0.14899316,-0.052108024,1.319928794,2.123259174,-2.641447591,-2.514130264,-2.404854424,-3.715702827,-2.972101662,-1.600448776,-3.496350527,-0.256577214 -3209,L192Y,-0.039728946,-0.005614497,0.031101041,-0.087413468,-0.947878926,-0.046987919,-0.030339538,-0.049118354,0.016018683,-0.034816721,0.023587728,0.05613717,0.006064912,-0.07168661,-0.103140325,-0.61651699,-1.279240861,1.136762899,1.562806313,-7.131275523,-5.95050705,-6.110677017,-8.04159523,-6.361701309,-9.191897011,-7.686589269,-0.189234146 -3210,T193A,-0.082039368,-0.02523072,0.017990193,-0.006502541,-0.014179751,-0.002881161,-0.018739441,-0.145339294,-0.002449966,-0.023528021,-0.026933419,0.057729772,-0.021749386,0.009600964,-0.022606046,-0.014632793,-0.013726709,1.153378849,2.522290216,-2.773426036,-2.385111595,-2.869509117,-2.99589859,-2.879722786,-2.736888092,-4.639915959,-1.060856275 -3211,T193C,0.029402227,-0.019284908,0.03207698,0.007130842,-0.007992231,0.015254234,0.012275295,0.046529158,0.007272092,-0.019070741,-0.019499075,0.05770244,0.006451519,0.037942613,-0.02368093,-0.026652302,0.01066784,1.325933007,2.691545222,-5.063013963,-3.949146378,-4.784970345,-5.136539536,-5.806743256,-5.637670303,-6.148862698,-3.250565728 -3212,T193E,-0.023697578,-0.055027854,-0.045130407,-0.029274082,-0.209827896,-0.043163081,-0.042359872,-0.005035284,0.017125616,-0.09717698,-0.012878728,-0.077667595,-0.012593218,-0.050609824,-0.007938339,-0.189587023,-0.230068769,1.495163424,2.213152233,-4.171435013,-3.467381966,-2.554351204,-4.81175209,-3.983860245,-6.039829559,-6.205675985,-0.329497743 -3213,T193D,0.024874887,0.039178288,0.010549181,-0.003289274,-0.07094539,0.021931107,0.033009825,0.016739949,-0.041528329,-0.002512433,0.080869009,-0.016066732,0.037165094,-0.005794643,-0.000783904,-0.06001254,-0.08187824,1.31205633,2.46737095,-3.901440347,-3.329843719,-2.842694122,-4.179172867,-3.19577494,-5.959716087,-5.106980478,-1.030134113 -3214,T193G,-0.010004476,-0.011059813,0.011663547,0.006739095,-0.038139974,-0.02345974,-0.021558552,0.001549601,0.007643478,-0.018125782,-0.003993844,0.02785773,-0.004530637,0.033839078,-0.020360889,-0.024483611,-0.051796337,1.235117378,2.449877744,-5.124488889,-3.270665428,-4.647929672,-4.926077774,-5.86345639,-6.914315178,-6.454675852,-2.34542645 -3215,T193F,0.018152858,0.006275395,0.014265679,0.013289842,-0.019831781,-0.059170982,-0.027460948,0.063766664,-0.021507539,-0.015958229,0.028509019,-0.041749787,0.070281144,-0.003261345,0.029841028,-0.024150746,-0.015512815,1.299989623,2.656061751,-2.302392981,-0.709044991,-3.064766571,-1.794213799,-3.722325615,-2.22161393,-2.746197947,-1.068535993 -3216,T193I,-0.045105803,-0.057146867,0.004338608,-0.000043,0.000771803,0.035180269,-0.061599348,-0.028612258,0.009497771,-0.069804403,-0.04448933,0.040886827,-0.032209611,0.007684384,-0.007770463,-0.021015332,0.022558938,1.177815081,2.492669546,-4.641043091,-3.331924347,-4.720671089,-4.657373329,-6.032173302,-4.463073387,-5.182928878,-2.231033751 -3217,T193H,0.025222996,0.012286865,0.068564979,0.05574968,0.024926095,0.137558574,0.018276304,0.032169688,-0.095103875,-0.007650536,0.032224265,0.077501195,0.059628763,0.078900156,0.032599203,0.004337792,0.045514397,1.208790157,2.807750016,-4.775592317,-4.023698837,-3.969603806,-5.330397858,-4.566403076,-5.987858009,-6.069661391,-1.831544373 -3218,T193K,-0.006335289,0.098920267,0.089801819,0.066860645,0.098222012,0.36645111,0.009616214,-0.022286792,-0.06848412,0.101877737,0.095962796,0.105249115,0.074354522,0.048063546,0.085657744,0.08067965,0.115764374,0.981517427,2.801542944,-5.683566974,-6.175537643,-4.604824837,-7.470636803,-4.529606064,-5.637229523,-5.92706598,-0.536928298 -3219,T193M,-0.033217488,-0.014407732,0.00513787,0.006329894,0.031074253,-0.020824796,-0.077436671,0.011001695,-0.044062978,-0.006522567,-0.022292896,0.081380775,-0.071105036,0.020231088,-0.007571301,0.10466757,-0.042519064,1.036897089,2.81709095,-5.021203539,-3.614391319,-5.383386429,-5.535293114,-6.237929855,-4.335016975,-5.399916452,-2.778858837 -3220,T193L,-0.022657796,-0.018740702,-0.007353933,-0.006878583,-0.064364734,0.024469712,-0.027412379,-0.017903212,-0.013162262,-0.03006112,-0.007420283,0.003273709,-0.017981574,0.01914718,-0.032904346,-0.065370369,-0.063359099,1.371633042,2.396912066,-2.07346852,-0.441383179,-2.569027695,-2.236837074,-4.187376343,-0.932718307,-3.451524286,0.971704961 -3221,T193N,-0.08169658,-0.013329423,-0.019257936,-0.004464028,-0.070475732,0.03457842,-0.09425275,-0.069140409,0.021555053,0.025592764,-0.05225161,0.016586093,-0.055101964,0.053419968,-0.062348024,-0.016298115,-0.124653348,1.160328634,2.481424064,-3.9112313,-4.097652222,-2.672217751,-4.182102173,-3.953627472,-4.650556885,-5.014979316,-0.527588009 -3222,T193Q,-0.021139368,-0.029135496,0.023303557,0.000580929,-0.027736966,0.034558165,-0.017545183,-0.024733553,-0.046314035,-0.005139463,-0.053131528,0.048164766,-0.001557653,0.037978298,-0.03681644,0.026575887,-0.082049819,1.671448915,3.643209181,-5.069660439,-4.080127487,-3.277920692,-6.922854645,-5.414491173,-5.652908196,-5.717092733,-0.409503591 -3223,T193P,-0.032785098,-0.213288802,-1.554578691,-2.239535951,-2.585087471,-0.024102722,-0.039672021,-0.025898174,-0.01313174,-0.18022422,-0.246353384,-1.639689955,-1.469467426,-2.125558605,-2.353513297,-2.524456566,-2.645718375,1.13366769,0.047235331,-7.54152103,-6.706070007,-6.908504608,-7.586830704,-8.14035009,-8.365849739,-7.933194762,-4.263459388 -3224,T193S,-0.029120728,-0.014000674,0.016574139,0.003528032,-0.042009722,-0.010574072,-0.043985055,-0.0142564,-0.006805148,-0.023588773,-0.004412575,0.013257611,0.019890666,0.02647941,-0.019423347,-0.048175943,-0.0358435,1.301175579,2.468360252,-2.382935455,-2.210181595,-1.6847976,-2.034777039,-2.902885033,-3.082036011,-4.604777259,-1.052631108 -3225,T193R,-0.036439898,0.039386964,0.077011459,0.041274339,0.040937953,0.256052041,-0.039807487,-0.033072309,-0.135897621,0.034197495,0.044576432,0.087802049,0.066220869,0.065123174,0.017425503,0.029881907,0.051993999,1.125678591,2.743463773,-5.362511148,-4.083679039,-3.675248428,-7.771865524,-4.763572418,-6.518190331,-5.53081505,0.244901606 -3226,T193W,-0.026055837,-0.04065817,-0.010479853,-0.021555079,-0.030497122,-0.001091514,-0.028382404,-0.023729269,0.001054612,-0.058000124,-0.023316216,0.000707638,-0.021667344,-0.018693103,-0.024417055,-0.029908081,-0.031086162,1.292942996,2.54436965,-6.196283296,-4.455610435,-6.386380569,-6.391801086,-6.408609711,-7.339014679,-7.182011733,-4.485218426 -3227,T193V,-0.045905886,-0.025494443,-0.000233005,-0.0110451,-0.000500627,0.011385969,-0.051169876,-0.040641895,-0.004320922,-0.046723269,-0.004265616,-0.009972449,0.00950644,0.00870964,-0.030799839,-0.016586339,0.015585086,1.223862287,2.535234418,-3.034419328,-2.040671104,-2.896910027,-2.717678429,-4.583653542,-2.93318354,-4.767009638,-0.723279789 -3228,T193Y,0.020231434,-0.059274043,0.005005136,0.004253916,-0.049908681,0.033477743,0.015343986,0.025118881,-0.077321639,-0.094206865,-0.024341221,0.007409041,0.00260123,-0.007069457,0.015577288,-0.074172918,-0.025644444,1.174667928,2.206485219,-4.293355396,-2.254556679,-4.5705214,-4.20582045,-4.883592163,-5.552286285,-5.552407122,-2.249611685 -3229,G194A,0.008782263,0.017356052,0.001437804,-0.012425522,-0.033181736,0.031924606,0.001089632,0.016474893,0.002720151,0.018591419,0.016120685,0.025930665,-0.023055058,-0.021452563,-0.00339848,-0.046788955,-0.019574516,1.223670094,2.457657378,-4.855669742,-4.202727654,-4.273010025,-5.703035385,-4.547327591,-5.552248055,-4.380491756,-3.966840633 -3230,G194C,-0.074171029,0.011931723,-0.012310443,-0.034681491,-0.14188896,0.043011468,-0.057019955,-0.091322103,0.022280808,-0.00199276,0.025856205,-0.007328091,-0.017292795,-0.031635864,-0.037727118,-0.134606817,-0.149171102,1.32564484,2.165305591,-7.750245682,-6.64422699,-6.748844246,-8.586031586,-7.260525574,-9.511600014,-6.490268289,-4.680526254 -3231,G194E,0.014516342,0.027503057,0.000281661,-0.003042425,-0.00654365,-0.025249903,0.013672339,0.015360344,0.013882435,0.013940988,0.041065125,-0.035487314,0.036050635,-0.035043554,0.028958704,-0.03922821,0.02614091,1.429570497,2.571178546,-3.39613277,-2.88639978,-3.034047318,-4.509987373,-2.280352936,-4.269876442,-3.179875556,-2.87586185 -3232,G194D,-0.004154446,0.00844115,-0.017152778,-0.004588643,0.011114738,0.036840527,-0.025085967,0.016777075,0.07682809,0.00493224,0.011950059,-0.018223326,-0.01608223,-0.030369739,0.021192453,-0.002955513,0.025184989,1.22503257,2.563584104,-3.980316139,-2.817754829,-3.53740799,-5.061411415,-3.315922096,-5.169084366,-4.376996685,-2.004404139 -3233,G194F,-0.041750885,0.013272291,0.014122516,-0.020603002,-0.689851161,0.070116993,-0.042452593,-0.041049176,0.029349053,0.002237664,0.024306918,0.004469867,0.023775164,-0.018695451,-0.022510552,-0.558466227,-0.821236094,0.991845749,1.516484973,-10.38313808,-8.193981972,-9.264329849,-11.9670813,-11.03188213,-11.45841513,-7.09898903,-4.684497614 -3234,G194I,0.019379544,0.028645283,-0.003325574,-0.079246773,-1.678925897,0.007397693,0.011286954,0.027472134,0.042378516,0.013476965,0.0438136,-0.036874309,0.030223161,-0.125970063,-0.032523483,-1.600163001,-1.757688793,0.861362858,1.325403081,-9.791129358,-8.898473358,-8.588000015,-10.38325981,-9.269397881,-11.81651572,-8.697470726,-7.718834949 -3235,G194H,-0.035300038,0.030389773,0.027950978,0.005488016,-0.086449922,0.280133591,-0.002978729,-0.067621346,-0.199042013,0.053026338,0.007753207,0.032131887,0.023770068,0.002708637,0.008267394,-0.102732166,-0.070167677,1.077306775,2.05380246,-7.541909418,-6.143261703,-6.343967796,-8.444393463,-7.016031929,-9.761892197,-6.237862782,-3.304987086 -3236,G194K,0.046313707,0.087883673,0.085578121,0.018087964,-0.08905312,0.272298564,0.066494864,0.026132549,-0.054457035,0.101891759,0.073875586,0.09687471,0.074281532,-0.048123713,0.08429964,-0.123657196,-0.054449043,1.519375409,2.391715016,-4.919286517,-4.248100273,-4.181224144,-6.281280266,-4.313723946,-5.572103958,-4.972720914,-2.835766182 -3237,G194M,-0.011401651,-0.002285493,-0.037325911,-0.010949585,-0.109029557,-0.024610685,-0.005294692,-0.01750861,0.02215354,-0.006998699,0.002427713,-0.005600647,-0.069051174,-0.055622646,0.033723477,-0.109410844,-0.108648269,1.45268838,2.314535329,-10.09625978,-9.033632256,-8.907912735,-11.07793341,-9.514082275,-11.94773823,-8.501595032,-7.709841927 -3238,G194L,-0.00046727,0.023047439,0.017005463,0.009155372,-0.735460234,0.016973981,0.01114606,-0.0120806,0.046643308,0.038563269,0.007531609,0.041870827,-0.007859901,-0.0062911,0.024601844,-0.491825368,-0.979095099,0.401022403,1.37432973,-8.890255872,-7.802645409,-7.983619331,-9.829518494,-8.159678398,-10.67581773,-7.014479061,-5.564248316 -3239,G194N,-0.000720232,0.033825713,-0.004738975,0.015689355,-0.099271407,0.070350346,0.025423651,-0.026864114,0.055741825,0.034879804,0.032771621,0.034015901,-0.043493851,0.011301694,0.020077015,-0.094221186,-0.104321628,1.514168428,2.456516177,-5.34141469,-4.150462212,-4.380742111,-6.999095779,-4.567073227,-6.609700119,-5.11638179,-2.76677789 -3240,G194Q,-0.04434509,0.008402235,-0.009199908,-0.013222728,-0.031244144,0.034588445,-0.070464251,-0.018225928,0.000797913,0.039416122,-0.022611652,0.016759347,-0.035159162,-0.022176141,-0.004269314,-0.039640001,-0.022848286,1.390047041,2.556897023,-5.439480342,-4.804229012,-4.693183952,-6.353939789,-4.449954689,-6.896094269,-5.221197789,-3.680813204 -3241,G194P,-0.007224916,0.005813494,0.001807947,-0.013510317,-0.198504302,-0.006181981,-0.018387812,0.00393798,0.022548848,0.00800095,0.003626037,0.014756261,-0.011140367,-0.010639677,-0.016380956,-0.164547341,-0.232461263,1.303043169,2.096507555,-7.099125357,-5.930844521,-5.064448067,-7.986045555,-7.661919334,-8.852369308,-6.304047142,-3.246495168 -3242,G194S,0.011767131,0.031855577,0.007260607,-0.00582411,-0.004549414,-0.0041583,0.012399873,0.011134389,0.025487838,0.028807457,0.034903696,0.028269878,-0.013748664,-0.010312018,-0.001336202,-0.000058,-0.009040828,1.300126048,2.636287204,-3.972095921,-2.854737823,-3.281643616,-4.961868523,-3.350341995,-5.41188765,-2.677201044,-3.339469533 -3243,G194R,-0.0773031,0.082218584,0.067644808,0.015580974,-0.30361416,0.400175459,-0.021685912,-0.132920287,-0.165588427,0.096712282,0.067724885,0.083939669,0.051349946,0.004491825,0.026670122,-0.234183127,-0.373045193,1.279592586,2.016132473,-6.05877892,-4.992234131,-4.79722142,-7.083854492,-5.735860069,-7.684724487,-5.690167498,-3.093343664 -3244,G194T,-0.023260199,-0.006455411,-0.014290415,-0.014268669,0.015216881,-0.022587613,-0.042398318,-0.004122079,0.033666173,0.012739801,-0.025650622,-0.005106729,-0.023474101,-0.009905254,-0.018632084,0.005605748,0.024828013,1.117138758,2.534675568,-4.533199487,-3.59620768,-3.989363174,-5.329018539,-3.534232414,-6.217175629,-4.12106268,-4.181370737 -3245,G194W,-0.009014715,0.005530593,0.025723607,-0.019923878,-1.17832734,0.073097183,0.009595603,-0.027625033,0.014104877,0.026574602,-0.015513416,0.045897108,0.005550106,-0.033537506,-0.00631025,-0.930259936,-1.426394744,0.704758656,1.361679353,-11.46661965,-9.903906769,-9.717849205,-12.64815269,-11.88463908,-13.17855051,-9.423639202,-9.985203535 -3246,G194V,-0.018017463,-0.010651925,0.00215504,-0.043235019,-1.411238447,0.051010722,-0.00814613,-0.027888796,-0.002977274,-0.015966756,-0.005337094,-0.026750619,0.031060699,-0.086958652,0.000488615,-1.374771944,-1.447704949,1.051049309,1.367314041,-8.869816852,-8.299149002,-7.826587402,-9.489960915,-8.154504349,-10.57888259,-8.042026569,-6.940368032 -3247,G194Y,-0.008314896,0.025333123,0.032637452,0.016243457,-0.707677085,0.005577294,-0.038945744,0.022315953,0.016295174,0.038082751,0.012583494,0.069178164,-0.00390326,0.02045074,0.012036173,-0.377634266,-1.037719903,0.68022161,1.490506922,-11.03783929,-9.262908928,-10.29203453,-11.89285094,-11.34127741,-12.40012464,-7.383035813,-5.86816079 -3248,E195A,-0.04038856,0.033053773,0.054837576,0.048389688,-0.107819608,0.214954758,-0.030259147,-0.050517972,-0.133553837,0.033375983,0.032731562,0.062891376,0.046783776,0.049993592,0.046785784,-0.093081462,-0.122557754,1.167460555,2.19751461,-2.434342494,-2.068805191,-2.57202771,-1.401891876,-3.040155418,-3.088832275,-4.206689898,-1.677416777 -3249,E195C,-0.163197019,0.012843383,0.012837212,0.004601143,-0.253589731,0.450957528,-0.141687053,-0.184706985,-0.241137991,0.098244252,-0.072557486,0.062943653,-0.037269229,0.031891573,-0.022689287,-0.215374871,-0.291804591,1.12933429,1.896195736,-5.346389555,-4.869292145,-6.046939125,-4.527680519,-5.747124077,-5.540911911,-6.617596878,-4.502375504 -3250,E195D,-0.038450163,0.043654578,-0.034573946,0.042486806,0.014874203,0.048300569,-0.042333592,-0.034566733,-0.008037309,0.016242106,0.071067049,0.015519003,-0.084666895,0.07425376,0.010719851,0.017147607,0.012600799,1.27185811,2.749825836,0.487344681,1.515512726,0.340776825,1.046860062,0.057464607,-0.523890816,-2.013093556,0.374354773 -3251,E195G,-0.012313756,0.015974408,-0.002192625,0.029745906,-0.014822188,-0.007474052,0.003180947,-0.027808458,-0.028329888,0.009281787,0.022667028,0.011502431,-0.01588768,0.037391389,0.022100422,-0.010988253,-0.018656122,1.061030322,2.465291839,-1.346216862,-0.608883347,-1.822422203,-0.260312088,-0.831826172,-3.207640503,-2.849593887,-1.59431066 -3252,E195F,-0.433225795,-0.466364546,-0.483548364,-0.799417851,-1.257844668,0.645962689,-0.541345186,-0.325106404,-0.132234863,-0.557189722,-0.37553937,-0.393655935,-0.573440792,-0.952462612,-0.646373089,-1.0642742,-1.451415135,3.60254646,3.082991877,-7.06187328,-6.766275215,-7.785464531,-5.79806916,-7.46172477,-7.497832726,-7.954126447,-6.380862934 -3253,E195I,0.435539185,0.073226077,-0.339150594,-0.203475087,-0.923341277,0.296172559,0.507872837,0.363205532,-0.071040402,-0.080068467,0.226520621,-0.393655935,-0.284645253,-0.35040262,-0.056547554,-0.763244204,-1.08343835,2.57133054,2.492226977,-6.495813696,-5.696652977,-6.842241341,-5.642756126,-6.711057831,-7.586360207,-7.298311657,-5.667384348 -3254,E195H,0.020034141,0.059504329,0.048392099,0.054972658,0.041473636,0.054948933,0.036076572,0.003991709,-0.079482198,0.049466021,0.069542637,0.054820139,0.041964059,0.070921207,0.039024108,0.036682636,0.046264635,1.090498317,2.811500526,-2.76107944,-1.707558334,-3.698705956,-1.841142448,-2.906142487,-3.651847977,-4.354161387,-2.540602906 -3255,E195K,0.022640048,0.04188953,0.040246296,0.016746624,-0.015181175,0.247029473,0.043274702,0.002005393,-0.134580943,-0.028236829,0.112015888,-0.0559858,0.136478392,-0.019103668,0.052596915,-0.078575811,0.048213461,1.326909262,2.244538031,-0.430225998,-0.525913307,-0.924449776,-0.383619873,0.193181496,-0.510328529,-3.27520133,-0.278912919 -3256,E195M,-0.122862521,0.234879272,0.100653852,0.065335057,-0.869914941,0.851551072,-0.001872893,-0.243852149,-0.216011861,0.425081511,0.044677033,0.08346532,0.117842383,0.27284667,-0.142176557,-0.33188044,-1.407949441,0.301396038,1.390383992,-5.696366808,-4.944514702,-6.064701576,-5.212213196,-5.734535759,-6.525868805,-6.293609577,-4.234397667 -3257,E195L,-0.084067545,-0.397965874,-0.376796379,-0.621911947,-1.055149919,0.428462973,-0.012882215,-0.155252875,-0.122192925,-0.407427401,-0.388504347,-0.368832351,-0.384760406,-0.664397593,-0.5794263,-0.972503826,-1.137796012,3.140778147,2.793087363,-5.059773688,-4.600127052,-5.802308189,-4.407946724,-5.207191765,-5.281294708,-5.996078766,-3.737203751 -3258,E195N,-0.049127584,-0.080440976,-0.036024399,-0.009626676,-0.076250219,0.145063588,0.023339083,-0.121594251,-0.025565013,-0.132597518,-0.028284434,-0.069868788,-0.00218001,-0.036508714,0.017255363,-0.132597518,-0.019902919,1.414912983,2.238588498,-0.466420021,0.247405975,-0.677656853,-0.045178062,-0.662883064,-1.193788101,-2.518482239,-0.7203244 -3259,E195Q,-0.020379293,-0.03850404,0.01013564,0.023373833,-0.013494444,0.039016452,-0.014336218,-0.026422367,0.035690356,-0.000887221,-0.076120859,0.034367086,-0.014095806,0.047237772,-0.000490107,0.025265498,-0.052254385,1.092391433,2.668485304,-1.6071119,-1.449537735,-2.124439713,-1.088717819,-1.423387398,-1.949476837,-3.428548039,-1.171889624 -3260,E195P,-0.010213574,-0.0000747,-0.007815853,0.028697209,0.007968436,0.004762216,0.011292844,-0.031719991,-0.003145787,0.010232372,-0.010381813,0.031815609,-0.047447315,0.077719195,-0.020324777,0.026309081,-0.010372209,0.881261428,2.670307651,-1.462621983,-0.846515022,-1.728384941,-0.136476791,-2.193450584,-2.408282578,-3.41096827,-2.089886501 -3261,E195S,0.00928002,0.041292016,0.033530855,0.073607039,0.001405108,0.060100043,0.036323552,-0.017763512,-0.012122454,0.032519831,0.0500642,0.035598137,0.031463572,0.09260433,0.054609748,0.01659494,-0.013784724,1.217359958,2.837393005,-0.872362848,-0.425751801,-1.37399144,-0.072151794,-1.317022667,-1.172896538,-2.809707,-1.070286251 -3262,E195R,-0.035118854,0.028829632,0.00760883,0.021661381,0.002125497,0.177633583,0.003986085,-0.074223792,-0.092137012,0.007145797,0.050513467,0.002305508,0.012912152,0.026446781,0.01687598,-0.015383633,0.019634626,1.19055673,2.554581262,-2.288504901,-1.929339661,-3.166964478,-1.44704171,-2.73958165,-2.159597008,-4.088444817,-0.800399063 -3263,E195T,0.008816169,0.070888909,0.048822095,0.046090901,0.004035174,0.056182639,0.019194368,-0.00156203,-0.042245905,0.060747032,0.081030785,0.041795337,0.055848852,0.027492379,0.064689422,-0.024227643,0.03229799,1.307373761,2.601030351,-0.977319864,-0.492728531,-1.288054619,0.101665535,-1.96776075,-1.239720955,-3.838517192,-0.997731875 -3264,E195W,-0.009267971,-0.159449441,-0.095869189,-0.13672318,-0.974195725,0.727539807,0.009353437,-0.027889378,-0.341020079,-0.059865081,-0.259033801,-0.062662716,-0.129075661,-0.279046712,0.005600352,-0.529160998,-1.419230452,2.193523213,2.351403295,-6.890139909,-5.913692284,-7.944561119,-5.859778343,-7.047232384,-7.685435417,-7.652963445,-5.72972932 -3265,E195V,-0.092857117,0.011106947,-0.090780039,-0.06345782,-0.774844864,0.741966726,-0.045999111,-0.139715122,-0.441554456,0.012402382,0.009811511,-0.137158339,-0.044401738,-0.174311361,0.047395721,-0.531930154,-1.017759574,1.760091631,2.003292338,-4.859701041,-4.101743065,-4.991648743,-4.234585014,-5.169783875,-5.800744507,-5.826411389,-3.717656516 -3266,E195Y,-0.250920199,0.0709309,-0.213553298,0.043641234,-0.562971902,0.779078983,-0.191604818,-0.310235579,-0.390785078,0.183172968,-0.041311168,-0.092625939,-0.334480656,0.169753267,-0.0824708,-0.268394182,-0.857549622,0.742020426,1.579156875,-5.477763542,-4.477521446,-6.185024925,-4.550022614,-5.845544647,-6.330704079,-6.759550108,-4.655115836 -3267,L196A,0.013511547,-0.023375649,-0.023564118,-0.013781833,-0.014103408,0.008321783,-0.013955126,0.040978219,,-0.027801499,-0.018949799,-0.028771326,-0.01835691,-0.015342286,-0.012221379,-0.016018021,-0.012188794,1.275895449,2.556860795,-0.091525543,0.003977318,-1.177837914,2.06191774,-0.944289711,-0.401395149,-1.537310894,0.414702027 -3268,L196C,0.069760885,0.008363096,0.021806966,0.050380668,0.029851428,0.022712749,0.07034801,0.069173759,,0.061388317,-0.044662125,0.04156188,0.002052051,0.025706085,0.075055251,0.049022749,0.010680106,1.189518643,2.987475843,-4.862336287,-3.754657616,-4.947948006,-4.66144416,-5.966102768,-4.981528885,-4.864213715,-2.920735483 -3269,L196E,-0.007915552,-0.041762433,-0.023924637,-0.02754187,-0.008205434,0.012594306,-0.028201504,0.0123704,,-0.032565289,-0.050959576,-0.009950605,-0.037898668,-0.067553008,0.012469268,-0.010071478,-0.00633939,1.224566242,2.396587879,-4.901392635,-3.602012383,-5.153275642,-4.003395119,-4.94045092,-6.807829109,-3.555781645,-3.193917153 -3270,L196D,-0.004506768,0.01938639,-0.020576894,-0.013560445,-0.00834174,0.02113384,-0.035816384,0.026802848,,0.052817106,-0.014044327,0.024710378,-0.065864165,0.025149336,-0.052270225,0.015939211,-0.03262269,1.186092017,2.550758115,-6.091553067,-4.49899131,-6.494629181,-4.752113411,-6.014953926,-8.697077507,-4.69568866,-3.872769361 -3271,L196G,0.034063842,0.005249751,0.022944604,0.009171503,-0.005089222,0.043119985,0.033669005,0.034458678,,-0.005992725,0.016492226,0.023149123,0.022740085,-0.012856845,0.03119985,-0.03617423,0.025995787,1.254713108,2.470105786,-2.851172108,-1.688632736,-4.065036774,-1.025415871,-3.378366348,-4.098408813,-2.367303133,-1.622627917 -3272,L196F,0.073438076,0.014319513,0.015627429,0.034377646,0.026951397,-0.02047721,0.06183005,0.085046102,,0.012486605,0.016152421,0.02442783,0.006827028,0.007126232,0.06162906,-0.014750519,0.068653313,1.334604692,2.685863573,-4.103047223,-4.338410919,-3.541874336,-3.519350853,-4.678425461,-4.437174545,-3.499190281,-1.847053595 -3273,L196I,0.044951287,0.012109375,0.033721096,0.005935301,-0.000868318,0.012479672,0.009325323,0.080577251,,0.016218656,0.008000093,0.048177492,0.0192647,0.002327349,0.009543253,-0.025111414,0.023374779,1.087457987,2.349038116,0.785169978,1.174452606,0.170403625,1.474884148,1.11228228,-0.006172768,-0.729955532,-0.782241086 -3274,L196H,0.055258306,0.040055925,0.035533666,0.019795314,0.032170135,0.002347854,0.042577023,0.067939588,,0.040594371,0.039517478,0.021187393,0.049879939,0.023581425,0.016009203,-0.005186299,0.069526568,1.285115094,2.716921905,-4.123775873,-2.682754578,-4.422295219,-3.744860168,-4.635109596,-5.133859802,-3.49085863,-3.435329776 -3275,L196K,-0.020741213,0.007963435,-0.030197788,-0.019914961,-0.023462475,0.064083112,-0.025243419,-0.016239006,,0.057766752,-0.041839883,-0.020833268,-0.039562307,-0.005261787,-0.034568135,0.045726058,-0.092651007,1.218124703,2.751691742,-4.212983546,-2.72179039,-4.460869209,-3.268997505,-3.91226857,-6.700992058,-3.591470374,-3.161827949 -3276,L196M,-0.034296794,-0.01369696,-0.023029124,0.016470899,-0.005650777,0.000164887,-0.028155211,-0.040438376,,0.006586835,-0.033980754,-0.002522618,-0.043535629,0.047986497,-0.0150447,0.008631687,-0.019933241,1.183163949,2.647552304,-2.204690822,-2.405503021,-1.89712075,-2.145755501,-1.284422409,-3.290652428,-3.623928296,-2.774963008 -3277,L196N,0.055590453,0.010300303,0.0183956,0.008056246,-0.017572607,-0.034108976,0.024540163,0.086640743,,-0.010163971,0.030764576,0.016378334,0.020412866,-0.010913511,0.027026002,-0.061884539,0.026739326,1.354000124,2.411725312,-4.630576305,-3.57007901,-5.114263214,-3.813794304,-5.078875877,-5.575869118,-3.650693733,-3.081068441 -3278,L196Q,0.039906886,0.011349414,-0.012393072,-0.001108468,0.020486085,0.020256301,0.035623537,0.044190235,,0.023234875,-0.000536047,-0.029850959,0.005064815,-0.043622296,0.041405361,-0.010698082,0.051670252,1.335417477,2.512888706,-4.582441042,-3.580046684,-5.079060745,-3.771986031,-4.018432205,-6.462679543,-4.164736193,-3.711897331 -3279,L196P,0.025067476,0.022386771,0.00192985,0.005183206,-0.0196861,0.02006191,-0.005732874,0.055867826,,0.023619277,0.021154264,-0.001332088,0.005191787,-0.006173528,0.01653994,-0.032193973,-0.007178226,1.225906852,2.40118045,-4.840714388,-3.513979713,-4.653661491,-3.890343033,-5.378092422,-6.767495277,-3.843820837,-3.551915553 -3280,L196S,0.046805005,0.014536052,0.015749972,0.001994899,-0.009026136,-0.013431392,0.033379226,0.060230783,,0.025336095,0.003736008,0.003606878,0.027893065,-0.018199872,0.02218967,-0.025258619,0.007206347,1.20193819,2.434580512,-2.462293846,-1.681970291,-3.112411125,-1.051349594,-3.125188171,-3.340550049,-2.58349418,-2.835945972 -3281,L196R,0.054531513,0.048388695,0.026178996,0.022509319,0.027352755,-0.010856282,0.045535786,0.063527239,,0.061714823,0.035062567,0.034104713,0.018253278,0.012762261,0.032256376,0.011214247,0.043491262,1.153649773,2.731051756,-2.527773511,-1.51847168,-2.493927834,-2.676964989,-2.358871117,-3.590631935,-2.305005502,-2.276691157 -3282,L196T,0.017822284,0.008293742,-0.010173642,-0.011032688,0.005459075,0.02100357,-0.000368212,0.03601278,,0.029090212,-0.012502728,0.007074099,-0.027421382,0.004799983,-0.026865358,-0.000503486,0.011421636,1.147152547,2.739505421,-0.057463766,0.303298035,-0.671542519,1.16073378,-0.528620354,-0.551187775,-0.760107644,-1.709858222 -3283,L196W,-0.001522253,-0.012566267,0.008912145,-0.012437375,-0.004021524,0.024990033,-0.005712509,0.002668003,,-0.016251841,-0.008880692,0.034916159,-0.01709187,0.000545886,-0.025420636,0.014174509,-0.022217557,1.200270332,2.547443944,-4.867541237,-4.314493546,-5.185991585,-3.990898521,-5.601040871,-5.245281662,-4.158895575,-2.726224217 -3284,L196V,0.010276203,-0.005372232,-0.023952923,-0.01545311,0.02295313,0.032045673,0.005247354,0.015305051,,0.007642746,-0.01838721,-0.002391491,-0.045514355,0.00025563,-0.031161849,0.034748499,0.011157761,1.075444182,2.612986375,1.718394193,1.828977112,0.977991356,2.75218502,1.796577965,1.23623951,-0.997966224,-0.190258578 -3285,L196Y,-0.006163127,0.02663334,-0.00985417,-0.002390429,-0.01937016,0.007733659,-0.026577181,0.014250928,,0.035320516,0.017946164,0.0059129,-0.025621239,-0.01010017,0.005319313,-0.047369987,0.008629668,1.239348798,2.512211098,-5.019418513,-3.660534775,-4.97061454,-4.118027916,-5.722555756,-6.625359581,-4.606030167,-2.773372767 -3286,L197A,-0.02373761,0.030910595,0.00679504,-0.653330671,-1.697822123,0.047662292,0.025849719,-0.073324938,-0.052145342,0.042514002,0.019307188,-0.00999663,0.023586709,-0.534969087,-0.771692255,-1.627592947,-1.768051298,1.91282619,1.569657129,-14.33855925,-14.68527869,-14.3262761,-14.03139686,-14.71773802,-13.93210659,-7.414769738,-2.455389584 -3287,L197C,-0.084688152,-0.001180709,-0.034669583,-0.931600656,-2.045410784,0.069618496,-0.071780545,-0.097595758,-0.049442393,-0.018621465,0.016260047,-0.031428102,-0.037911064,-0.697853852,-1.16534746,-1.94427319,-2.146548378,1.900936641,1.450141887,-15.19058721,-14.54637556,-15.68886865,-16.55536907,-14.27505969,-14.88726307,-8.437451121,-4.702317055 -3288,L197E,-0.059060912,0.02084969,0.037753186,-1.282698409,-2.296573983,-0.023808541,0.000554904,-0.118676728,0.05573352,-0.013732545,0.055431925,0.062615367,0.012891005,-0.934873476,-1.630523341,-2.319595511,-2.273552455,1.673054163,1.14794094,-16.77133755,-16.53854823,-17.92340133,-17.64644926,-16.39650708,-15.35178188,-8.391789159,-5.435059968 -3289,L197D,-0.080197538,0.048740721,-0.032296513,-2.055621736,-2.265152026,-0.049183194,-0.029963811,-0.130431264,-0.012699574,0.082961884,0.014519558,-0.016987437,-0.047605588,-2.44511489,-1.666128581,-2.01029299,-2.520011061,0.332960202,0.431602035,-18.96284668,-18.90223913,-21.19070544,-19.86143558,-17.28258393,-17.57726931,-10.1188955,-7.750218857 -3290,L197G,-0.024151718,-0.010227798,-0.016402429,-0.896759172,-2.046874712,-0.023708635,0.00607678,-0.054380216,-0.008365334,0.004578706,-0.025034301,-0.026898364,-0.005906493,-0.654828895,-1.138689448,-1.865191655,-2.228557768,1.950233434,1.501140493,-16.33516712,-15.96907021,-17.40682607,-17.04076817,-16.12968028,-15.12949089,-7.135209439,-3.209124218 -3291,L197F,-0.010194751,0.105238352,0.03118113,0.024397783,-1.641900013,0.095142783,0.012685096,-0.033074598,-0.025305865,0.154096372,0.056380331,0.047052595,0.015309665,0.051272586,-0.00247702,-1.303337775,-1.980462251,0.690390095,1.33141229,-10.22195601,-10.28533062,-11.30362936,-10.66267838,-7.877249527,-10.98089219,-6.683239695,-3.349526525 -3292,L197I,-0.084387601,-0.032492639,-0.082799487,-0.040662013,-0.537680195,0.001915045,-0.05453011,-0.114245092,0.002426232,-0.030141542,-0.034843735,-0.070846197,-0.094752776,-0.046935336,-0.034388689,-0.388710859,-0.686649531,1.585954166,2.004559513,-9.811884001,-9.677166199,-12.29070658,-10.0483804,-9.908395042,-7.134771782,-6.180701676,-2.217429491 -3293,L197H,-0.081098016,0.007884811,-0.003634123,-0.093895396,-1.660891852,0.067213149,-0.016498376,-0.145697656,-0.087842993,-0.00459304,0.020362662,-0.021475574,0.014207329,-0.13997286,-0.047817931,-1.487030083,-1.834753621,1.146197058,1.369251595,-16.6228701,-15.504476,-18.08422813,-18.50733913,-14.39391035,-16.6243969,-9.102078377,-6.37422245 -3294,L197K,-0.13044991,0.070248184,0.022180473,0.034133069,-1.710046227,0.121101452,0.035201587,-0.296101407,-0.114400745,0.057813629,0.082682738,0.01156402,0.032796925,-0.051630458,0.119896596,-1.455657648,-1.964434805,0.733091222,1.324843576,-16.58521245,-16.64350282,-19.1760352,-16.87603623,-14.61302065,-15.61746734,-9.1729386,-6.753484387 -3295,L197M,-0.197201075,0.069362302,-0.050992398,-0.031921177,-0.51859851,0.065988873,-0.131097712,-0.263304437,0.041392685,0.203094811,-0.064370207,0.118476864,-0.22046166,0.056865042,-0.120707396,-0.282603888,-0.754593131,0.575632978,1.496304006,-8.332552968,-9.189344131,-9.990128197,-8.061936134,-6.483475517,-7.937880859,-6.7787166,-4.407740592 -3296,L197N,-0.079909305,-0.008459412,-0.093345703,-0.405814737,-2.089523293,-0.024413894,0.044211771,-0.20403038,0.018275957,-0.054410117,0.037491294,-0.146672608,-0.040018798,-0.386474346,-0.425155128,-1.780956219,-2.398090366,1.634735838,1.423928587,-15.86103478,-16.54899535,-15.53772618,-17.70119572,-14.47622852,-15.04102815,-8.188958884,-5.500778401 -3297,L197Q,-0.129075533,-0.077810518,-0.065311732,-0.301647647,-1.88757772,-0.010478116,-0.060071821,-0.198079244,-0.006825987,-0.110336903,-0.045284133,-0.11328962,-0.017333843,-0.287902847,-0.315392446,-1.850592147,-1.924563293,1.563353071,1.398476591,-14.63586214,-15.28351138,-15.77565985,-15.11880817,-12.71246116,-14.28887012,-8.924597773,-6.145635274 -3298,L197P,0.016845873,-0.016613922,-0.00724059,-1.353541489,-1.975856504,-0.038515171,0.011606027,0.022085719,-0.005427859,-0.027375642,-0.005852202,-0.054556364,0.040075184,-1.310168591,-1.396914386,-1.987430107,-1.964282901,2.772559482,1.890368415,-15.2799201,-15.42495692,-16.68807301,-14.87172769,-15.03188857,-14.38295432,-8.175279796,-6.012896349 -3299,L197S,-0.022285811,-0.001438346,-0.02522251,-0.367586211,-1.729367627,-0.008146814,-0.015491121,-0.0290805,-0.00822033,0.004619092,-0.007495784,-0.020380217,-0.030064803,-0.316054499,-0.419117923,-1.658840641,-1.799894612,1.511261138,1.416924946,-14.59886027,-15.02694459,-14.0346619,-15.72784817,-14.12911869,-14.075728,-7.540516268,-4.673359822 -3300,L197R,-0.055881973,0.076828662,0.064752299,-0.054788797,-1.824107048,0.395000823,-0.002538063,-0.109225883,-0.199208228,0.080783347,0.072873976,0.023049747,0.10645485,-0.114801169,0.005223576,-1.60147995,-2.046734146,0.969068422,1.334456217,-14.69292516,-14.86406073,-15.91568047,-15.4926286,-13.37062941,-13.82162656,-7.999536632,-5.541707484 -3301,L197T,-0.017429553,-0.005187169,-0.002833728,-0.4815101,-1.970737178,0.006274136,0.007599422,-0.042458527,-0.020083584,0.01336471,-0.023739048,-0.035374941,0.029707486,-0.322073525,-0.640946674,-1.828194795,-2.113279561,1.438013215,1.371344602,-14.57646696,-14.5348147,-16.65854028,-13.73897684,-14.65837626,-13.29162673,-8.118491673,-4.387373447 -3302,L197W,0.028174208,-0.018779027,0.033650542,-1.734340475,-2.253095968,0.102615383,0.057163931,-0.000815515,-0.002015291,-0.044493448,0.006935395,-0.002581718,0.069882802,-1.821494249,-1.6471867,-2.517006117,-1.989185819,0.637419759,0.67546385,-14.60413,-14.72904951,-15.83919521,-15.53082522,-12.56078399,-14.3607961,-8.715948681,-5.836764771 -3303,L197V,-0.04725801,-0.058101129,-0.084076317,-0.11158465,-1.583193307,0.054976993,-0.008788948,-0.085727072,-0.010002618,-0.09692955,-0.019272707,-0.143236,-0.024916634,-0.179781813,-0.043387486,-1.493985538,-1.672401075,1.386372183,1.419947704,-10.72377329,-9.668044037,-13.3121311,-10.38218953,-11.49853909,-8.757962692,-6.562908558,-1.8593384 -3304,L197Y,-0.050337507,0.023080418,-0.030729268,-0.24669205,-1.821305888,0.011798279,0.006615313,-0.107290327,-0.026597768,0.023739937,0.022420899,-0.111166809,0.049708273,-0.26616433,-0.227219769,-1.553564894,-2.089046882,1.41708667,1.410020259,-15.81449498,-15.11707778,-18.65466459,-16.45438425,-12.41579762,-16.43055068,-8.736434597,-6.108585189 -3305,T198A,-0.02430502,0.009397561,0.01368525,-0.012103678,-0.05716975,0.103005075,0.009123947,-0.057733987,0.051051028,-0.047580786,0.066375908,0.034468539,-0.007098039,-0.019009264,-0.005198092,-0.057902269,-0.05643723,1.234517724,2.364232475,-2.518744803,-2.482821213,-2.49092778,-2.935290581,-1.860446693,-2.824237747,-4.003327582,-0.123421964 -3306,T198C,0.009769318,0.068221059,0.006597798,-0.008918587,-0.095859568,0.024798522,0.015738787,0.003799849,0.029790063,0.06365219,0.072789927,0.021671665,-0.008476069,0.018530547,-0.03636772,-0.084723769,-0.106995366,1.291317871,2.309880284,-6.822244203,-6.24074086,-6.074037964,-7.737159187,-6.574850327,-7.484432678,-7.405995827,-4.21485153 -3307,T198E,0.009339796,0.007257771,0.015293863,-0.004027421,-0.0266382,-0.013795319,-0.011827491,0.030507082,0.065577739,0.00623732,0.008278221,0.01039142,0.020196306,-0.01322481,0.005169968,0.023226232,-0.076502632,1.063654891,2.643429168,-4.195633488,-3.606579422,-4.210905853,-5.269645081,-3.125594513,-4.765442574,-4.685455694,-1.472514098 -3308,T198D,-0.062204837,-0.034206545,-0.036889812,-0.04560963,-0.222104265,0.050914265,-0.040350261,-0.084059413,-0.037051487,-0.064172053,-0.004241037,-0.010442395,-0.063337229,-0.037730207,-0.053489053,-0.142463694,-0.301744835,1.56681266,2.358869154,-5.909622392,-3.380208321,-7.113690628,-8.27382679,-4.487704788,-6.292681435,-6.102059639,0.051128202 -3309,T198G,-0.012654676,-0.016008398,-0.02678368,-0.036064507,-0.073106841,0.019895788,0.004219222,-0.029528573,0.040418094,-0.028591704,-0.003425092,-0.017403992,-0.036163368,-0.046874562,-0.025254452,-0.053916619,-0.092297063,1.4106899,2.57426162,-5.18503795,-4.493016418,-4.682470024,-6.675770844,-5.132036972,-4.941895493,-5.559376275,-0.226788263 -3310,T198F,-0.004546573,-0.005452129,0.003756651,-0.017958787,-1.565430762,0.000105479,0.035116276,-0.044209421,0.091106044,-0.042845007,0.03194075,-0.017951997,0.025465298,-0.061819418,0.025901844,-1.315426468,-1.815435055,0.852603014,1.345923356,-8.527825568,-8.332944695,-8.113537155,-8.88006041,-7.659754257,-9.652831322,-9.154796618,-6.728775792 -3311,T198I,-0.063273551,-0.009961161,-0.012107407,-0.085033599,-1.705973767,-0.01314193,-0.067487959,-0.059059143,0.065676026,-0.010512479,-0.009409843,0.005400666,-0.029615479,-0.084806445,-0.085260752,-1.489354363,-1.922593171,0.836590065,1.331621733,-6.336802771,-6.905911308,-5.945918968,-6.747490044,-5.190016708,-6.894676826,-7.270542271,-3.956831734 -3312,T198H,-0.024420169,-0.020859985,-0.017254343,-0.011948385,-0.10664656,0.033301512,-0.033646042,-0.015194296,-0.004144022,-0.042091979,0.00037201,-0.020350095,-0.014158591,-0.028398549,0.004501779,-0.085115118,-0.128178001,1.345602054,2.295107697,-5.633867694,-6.016578903,-4.906433502,-6.670037262,-4.857148438,-5.719140366,-5.774379663,-1.767284137 -3313,T198K,-0.010990669,-0.028021214,-0.014451903,-0.049482217,-0.066967809,0.037599825,0.014886719,-0.036868056,-0.031905243,-0.026245745,-0.029796682,0.001015842,-0.029919647,-0.022781055,-0.076183378,-0.041048667,-0.092886951,1.411304952,2.545440026,-1.857744144,-1.726519714,-1.70435305,-2.052472115,-1.256438072,-2.548937767,-3.931617575,-0.774115152 -3314,T198M,-0.048000773,-0.009600803,-0.024409602,-0.026338835,-0.368987389,0.040685648,-0.053749923,-0.042251622,0.060363381,-0.038612326,0.01941072,0.001029955,-0.049849159,-0.013053687,-0.039623982,-0.289835669,-0.448139109,1.190991382,1.805726867,-5.748700327,-6.059445801,-5.557713348,-5.866371254,-4.575555023,-6.684416206,-7.447848932,-4.662686543 -3315,T198L,-0.008753832,0.032829695,-0.002492343,-0.004815249,-0.607306196,0.047934061,0.0020407,-0.019548364,0.029809652,0.033629404,0.032029985,-0.005387744,0.000403059,-0.006306142,-0.003324356,-0.391995558,-0.822616834,0.951109855,1.582936389,-3.82050249,-4.089446068,-3.650866974,-4.175989098,-3.045033974,-4.141176338,-5.647929781,-2.699047205 -3316,T198N,-0.023748906,0.019390051,-0.036500896,-0.040954833,-0.088840844,0.054281907,0.005911475,-0.053409287,0.068625935,0.033721728,0.005058374,-0.057460539,-0.015541253,-0.009027636,-0.072882029,-0.067981655,-0.109700033,1.138919645,2.312666501,-3.680244722,-2.387767265,-3.627151176,-5.68516526,-2.902251938,-3.79888797,-5.754093885,-0.114206959 -3317,T198Q,-0.046244981,-0.033257141,-0.0795992,-0.03555395,-0.087078312,0.04037621,-0.049239675,-0.043250287,-0.005271306,-0.029133691,-0.03738059,-0.130922875,-0.028275524,-0.023257751,-0.047850149,-0.090148542,-0.084008082,1.393035116,2.354162419,-2.789567009,-3.296104805,-2.590100754,-3.18728289,-1.909681839,-2.964664757,-4.254681307,-1.499978185 -3318,T198P,-0.047288657,0.000771711,-0.015981098,-0.021019636,-1.642965451,0.073107128,-0.01773734,-0.076839974,0.040775412,-0.024788157,0.026331579,-0.003420505,-0.028541691,-0.035166423,-0.006872849,-1.509094126,-1.776836775,0.71936057,1.324869684,-5.423520448,-3.876521866,-5.228850967,-5.553514915,-4.894772018,-7.563942474,-4.174025279,0.377110995 -3319,T198S,0.03354011,0.01913275,0.004015326,-0.009908356,0.034374676,0.030568501,0.042863787,0.024216433,0.027171957,-0.011798397,0.050063897,-0.026843441,0.034874092,-0.03401127,0.014194558,0.013083553,0.055665799,1.329394115,2.732324823,1.264865793,1.147486298,1.638088768,1.224643387,1.282012894,1.032097618,-1.205200402,1.6751538 -3320,T198R,-0.031109734,0.008442273,0.010616511,-0.014291511,-0.130710025,0.121282454,-0.00567576,-0.056543708,-0.004114056,-0.012427156,0.029311702,0.01342378,0.007809242,-0.010707176,-0.017875846,-0.09393392,-0.167486129,1.312071236,2.273098808,-3.601698499,-4.096873184,-2.818957237,-4.457721588,-3.196193146,-3.438747337,-5.277946362,-1.188391208 -3321,T198W,-0.043606541,-0.002922031,-0.012878631,-1.303720614,-1.982114442,0.101650931,-0.015805788,-0.071407293,-0.009609625,-0.041578718,0.035734657,-0.043405132,0.01764787,-1.243658798,-1.36378243,-1.927556396,-2.036672488,2.846229743,2.000198331,-9.119641844,-8.919905792,-8.540743767,-10.10304659,-8.104820213,-9.929692863,-9.551342146,-7.836974435 -3322,T198V,-0.039122313,-0.028211985,-0.023886819,-0.034497706,-1.215136884,0.068242245,-0.003756848,-0.074487777,0.04346811,-0.067264877,0.010840908,-0.042636762,-0.005136876,-0.062503481,-0.00649193,-0.863313958,-1.56695981,1.077372069,1.461354052,-5.806068761,-5.585182373,-5.511414352,-6.19105201,-5.042835426,-6.699859642,-6.523033714,-2.797522935 -3323,T198Y,-0.021000305,0.014599615,0.004004614,-0.020075151,-1.536340093,0.059665484,-0.017884,-0.02411661,0.047285371,0.026498368,0.002700861,-0.002039731,0.010048959,-0.042027896,0.001877595,-1.290292175,-1.78238801,0.759389395,1.336104917,-8.684597238,-9.470485275,-8.217684799,-9.017091934,-7.23429744,-9.483426743,-8.227637148,-4.653092039 -3324,L199A,-0.027031688,-0.017196592,-0.028033655,-0.014487157,0.015100529,0.0000887,-0.027035427,-0.027027949,0.046251779,0.004176744,-0.038569928,-0.020353345,-0.035713965,0.012653535,-0.041627849,0.015309503,0.014891555,1.200850847,2.707344788,1.95162793,1.194707817,1.485252678,2.490416359,1.909647011,2.678115784,-0.687031912,1.97142271 -3325,L199C,-0.078652536,-0.010805174,0.000306769,-0.030406042,0.012399982,0.048468403,-0.06959473,-0.087710341,0.044969564,0.030666324,-0.052276672,0.027562775,-0.026949237,0.039484789,-0.100296873,0.026342132,-0.001542168,1.251126816,2.777033081,-3.416662003,-3.433863495,-3.438786865,-3.338841454,-3.536896133,-3.334922066,-6.324529532,-3.700717006 -3326,L199E,0.02022208,-0.037953197,-0.032597793,-0.021098059,-0.004804214,0.001247656,-0.004034397,0.044478556,0.007996771,-0.039667552,-0.036238841,-0.04377618,-0.021419405,0.002678643,-0.04487476,0.015414076,-0.025022504,1.3446759,2.806610344,1.590117041,1.302687744,1.299540833,1.559013443,1.318516762,2.470826424,-2.037036941,1.599302077 -3327,L199D,-0.040595208,-0.039818674,-0.054353713,-0.040196833,-0.058771055,-0.064835412,-0.062775807,-0.018414609,0.058867015,-0.016726929,-0.062910418,-0.090383995,-0.018323431,-0.021542146,-0.058851519,-0.053720238,-0.063821871,1.435469301,2.507989315,1.057590759,0.675891266,0.571486458,1.325356667,1.12924086,1.585978546,-2.600787959,0.828957744 -3328,L199G,-0.033864266,-0.008566498,-0.0407965,-0.022544106,-0.004201456,-0.005685898,-0.046428623,-0.021299908,0.019575926,0.00593859,-0.023071586,-0.032608424,-0.048984575,-0.016100922,-0.02898729,-0.011903493,0.003500581,1.322113845,2.63932888,-0.089580037,-0.36398304,-0.060746178,0.589893684,-0.356437454,-0.256627197,-4.250416125,0.270899409 -3329,L199F,-0.017045945,0.011424523,0.01892704,0.003213487,0.063373193,-0.101687211,-0.07115254,0.03706065,0.067043606,0.05269354,-0.029844495,0.075124161,-0.037270082,0.054314108,-0.047887135,0.121761435,0.004984951,1.036155153,2.988611183,-3.257868896,-3.353865646,-3.214160736,-3.694899544,-2.986871628,-3.039546928,-6.037922518,-3.552481743 -3330,L199I,0.006648491,0.062682639,0.00522337,-0.007024595,0.062772634,-0.03384584,-0.011678719,0.0249757,-0.000792968,0.116743567,0.00862171,0.014560597,-0.004113858,0.012466992,-0.026516181,0.091146146,0.034399122,1.09554221,2.794999549,-1.194504732,-1.65236911,-1.279617973,-1.01912767,-1.091874306,-0.929534599,-4.003958445,-1.484925377 -3331,L199H,-0.048182027,-0.011434148,-0.038469085,-0.00428956,-0.004857554,-0.019914162,-0.070689457,-0.025674596,-0.040655466,0.006449249,-0.029317544,-0.022970801,-0.053967368,0.025123883,-0.033703003,-0.001196203,-0.008518904,1.671448915,3.643209181,-1.522307787,-1.233090714,-1.216145424,-1.621006851,-1.369052811,-2.172243134,-4.080918322,-1.343540111 -3332,L199K,-0.082210785,-0.009505674,-0.055498447,-0.078800065,0.048501146,0.090858671,-0.094174931,-0.070246638,-0.037324705,0.027943466,-0.046954814,-0.075362003,-0.035634891,0.003913019,-0.161513149,0.036707647,0.060294645,1.068847326,2.622453332,0.450106583,0.48516745,0.662854179,0.447277229,0.747306717,-0.092072662,-2.620869448,1.382620794 -3333,L199M,-0.033186398,0.030030665,-0.030539012,0.011792131,0.041551904,-0.030350807,-0.032512778,-0.033860018,-0.017546557,0.08883072,-0.028769391,0.002586035,-0.063664059,0.02957501,-0.005990749,0.1191808,-0.036076993,1.13745858,3.037313811,-1.271333499,-1.49349955,-1.249699219,-1.10516378,-1.402469414,-1.105835533,-4.45667329,-0.923037538 -3334,L199N,-0.022179943,-0.089026972,-0.059748346,-0.086126937,-0.104307023,0.009643383,-0.0000301,-0.044329786,-0.002429429,-0.160185085,-0.017868858,-0.113335029,-0.006161662,-0.101802312,-0.070451561,-0.10956398,-0.099050066,1.519985004,2.40768186,-0.685409805,-0.802824226,-0.517895821,-1.015296661,-0.126506271,-0.964526047,-3.873168786,-0.380882008 -3335,L199Q,-0.03683636,0.015745131,-0.020020164,-0.017761958,-0.02665737,-0.015306065,-0.07681909,0.003146371,0.008164023,0.02647021,0.005020051,-0.029426414,-0.010613914,-0.040848432,0.005324516,-0.072144269,0.018829529,1.255459217,2.31068285,0.207358647,0.054607925,0.333608261,0.433601601,0.368667175,-0.153691727,-3.151451959,0.42151381 -3336,L199P,-0.053286605,-0.0251147,-0.027665229,-0.030893433,-0.013699019,0.003003652,-0.068002324,-0.038570886,0.004672419,0.011357622,-0.061587021,-0.016523791,-0.038806667,-0.008906617,-0.052880249,0.00829819,-0.035696227,1.277305372,2.668884747,2.607260886,2.125410118,2.26823056,3.014168175,2.800000595,2.82849498,-0.325263983,2.628795874 -3337,L199S,-0.033089777,-0.023175113,-0.034415473,-0.016419681,0.004816356,-0.020471327,-0.038589716,-0.027589837,0.006424973,-0.017909915,-0.02844031,-0.01681735,-0.052013595,-0.008628976,-0.024210386,0.02447777,-0.014845059,1.202973848,2.612738961,0.72763315,0.434434555,0.680519577,0.724953094,0.999355721,0.798902802,-2.285986325,0.70741059 -3338,L199R,-0.048343644,-0.031977845,-0.037559974,-0.028883189,-0.020615909,0.002825302,-0.061342596,-0.035344692,-0.004254031,-0.018456948,-0.045498742,-0.060877111,-0.014242837,-0.022052544,-0.035713833,-0.03388878,-0.007343037,1.313536315,2.535703096,0.222702208,0.459859802,0.05245153,1.133191315,0.219049904,-0.751041512,-3.231284381,0.701463356 -3339,L199T,-0.030411367,-0.018536086,-0.045893348,-0.007034096,0.004982806,-0.007393435,-0.025793229,-0.035029505,0.03159419,0.00592441,-0.042996581,-0.039581106,-0.05220559,0.036954581,-0.051022773,0.019113566,-0.009147954,1.151316067,2.60658435,0.390183598,-0.157049606,0.325246689,0.56849118,0.676636864,0.537592865,-2.025771979,0.346320251 -3340,L199W,-0.015509895,0.002816079,-0.016694373,0.00904024,-0.034159285,-0.005438928,-0.011210651,-0.019809139,0.019608237,0.000505217,0.005126941,0.004011877,-0.037400623,-0.025688593,0.043769073,-0.014400561,-0.053918008,1.152331745,2.430418174,-3.118208087,-2.865300835,-2.951775208,-3.251074608,-3.006463509,-3.516426277,-6.185233166,-3.027377113 -3341,L199V,-0.045907332,-0.011172241,-0.05700909,-0.02239062,-0.018299501,0.025046952,-0.045953977,-0.045860686,-0.009813985,0.025448538,-0.04779302,-0.083369994,-0.030648186,-0.009151973,-0.035629266,-0.01427887,-0.022320131,1.247363549,2.50703257,0.334227567,-0.220866104,0.020062904,0.506673843,0.355274193,1.009992996,-2.161832686,-0.230118011 -3342,L199Y,-0.026289551,-0.054758716,-0.076301005,-0.103720382,-0.046826307,0.011961406,-0.028762876,-0.023816225,-0.078099681,-0.057563183,-0.051954248,-0.097048491,-0.055553518,-0.108912217,-0.098528547,-0.10149302,0.007840407,1.377105667,2.234997027,-1.698281232,-1.814607201,-1.286404877,-2.148637505,-1.104500954,-2.137255623,-4.591965463,-1.453454387 -3343,A200C,-0.026611937,0.047657519,0.034244771,0.057625989,-0.053922218,0.014591848,-0.056806994,0.003583121,0.055491137,0.096289508,-0.00097447,0.101370966,-0.032881424,0.074326689,0.040925289,0.036042915,-0.14388735,1.110270999,2.803064708,-6.33652859,-6.165485382,-6.927766411,-6.331905533,-5.913112808,-6.344372818,-7.559379047,-6.191135922 -3344,A200E,-0.029374586,0.025307143,-0.039179385,-0.028328869,-0.011045614,0.027760609,-0.032732952,-0.026016219,0.081445845,-0.02096752,0.071581805,-0.015283969,-0.0630748,-0.002189434,-0.054468304,0.000189394,-0.022280621,1.300420265,2.768342995,-2.06435992,-1.507211639,-2.639424301,-2.996210167,-1.231242271,-1.94771122,-3.736388557,-0.262873058 -3345,A200D,-0.070584728,-0.014830798,-0.051548853,-0.000508647,-0.046943255,0.024348387,-0.121569668,-0.019599788,0.118264852,-0.030035781,0.000374185,-0.001506212,-0.101591494,0.031689415,-0.032706708,0.003171994,-0.097058503,1.165366601,2.63846726,-2.948624658,-2.068119225,-2.659374023,-4.752940132,-2.239861061,-3.02282885,-3.492366709,-0.980329441 -3346,A200G,-0.007804846,0.006225709,0.008956813,0.019080766,0.01257536,0.024556248,-0.006477254,-0.009132437,0.068433832,-0.015883937,0.028335355,0.021956316,-0.004042691,0.031197249,0.006964282,0.044902978,-0.019752258,1.215398119,2.910565384,-1.978299922,-2.338692245,-2.365577271,-1.402096146,-1.842778946,-1.942355003,-3.992203035,-1.663032976 -3347,A200F,-0.018269591,0.063130521,0.036109897,0.033945436,-0.236304149,0.071027026,-0.009470827,-0.027068354,0.001520594,0.060043083,0.066217958,0.036175366,0.036044428,0.033693286,0.034197586,-0.208006904,-0.264601393,1.33632919,2.053517302,-5.242302884,-4.960608925,-6.154960365,-5.737094582,-4.068340485,-5.290510063,-6.155416663,-4.428297016 -3348,A200I,-0.029431769,-0.010061659,-0.04120711,-0.014574678,-0.106340364,0.052785943,-0.052675551,-0.006187986,0.103575022,0.008250075,-0.028373392,-0.014977156,-0.067437063,0.007808784,-0.03695814,-0.089685625,-0.122995103,1.538507605,2.53660855,-5.603560628,-5.41130365,-6.753201004,-5.815659798,-4.64561525,-5.392023438,-6.260061696,-4.579612149 -3349,A200H,-0.039130902,-0.002675746,0.01115046,0.006564284,-0.037725566,0.031114033,-0.010355144,-0.06790666,0.108252274,-0.034216091,0.0288646,-0.048207073,0.070507992,-0.016409016,0.029537584,-0.039301588,-0.036149543,1.308833034,2.463800836,-3.2820957,-3.246235176,-3.498612625,-3.588377975,-2.1990896,-3.878163124,-4.624581411,-2.955316012 -3350,A200K,-0.046845057,0.057763844,0.04576431,0.087282399,0.018088694,0.046833128,-0.063053213,-0.030636901,0.082408805,0.080072716,0.035454971,0.111316635,-0.019788015,0.190675445,-0.016110648,0.110181067,-0.074003679,1.190057792,2.955570893,-1.477010083,-1.312795235,-2.202541344,-1.82094339,-0.155411606,-1.893358841,-2.830076528,-1.282424531 -3351,A200M,-0.026123704,-0.08255014,-0.003295781,0.011973399,-0.146867379,-0.018347889,-0.032214754,-0.020032654,0.047360281,-0.098847833,-0.066252447,-0.014977156,0.008385595,-0.014467611,0.038414409,-0.158538161,-0.135196597,1.459058417,2.24694427,-5.356369023,-5.305223801,-6.302295021,-5.559234154,-4.548955055,-5.066137085,-6.45680444,-4.702264092 -3352,A200L,-0.001933022,0.02798274,0.030829616,0.034769545,-0.124382733,0.214731182,0.02344186,-0.027307903,-0.069044221,0.015051492,0.040913987,0.02127924,0.040379992,0.02578114,0.043757949,-0.11692251,-0.131842955,1.425823516,2.354397789,-4.361027431,-4.179353676,-5.614958961,-4.580447685,-3.134753456,-4.295623375,-5.62626058,-3.46046372 -3353,A200N,-0.011494979,0.052525012,0.041116671,0.078990531,0.02956398,0.021742548,-0.04373457,0.020744613,0.071085774,0.070103069,0.034946955,0.075302278,0.006931064,0.114835931,0.04314513,0.013645377,0.045482583,1.110969013,2.691206778,-2.879820033,-2.288303352,-2.74953141,-4.123475548,-2.473652351,-2.764137505,-4.640253976,-2.380705622 -3354,A200Q,0.050251821,-0.020079153,0.013416539,0.001007609,-0.005148779,0.031591423,0.068517009,0.031986632,0.061461126,-0.055616366,0.01545806,-0.030280844,0.057113921,-0.008950219,0.010965436,-0.014741093,0.004443535,1.36370701,2.620902394,-1.920512555,-1.749687454,-2.592502975,-1.898997017,-1.17666391,-2.184711418,-4.013512981,-1.596853708 -3355,A200P,-0.028145702,-0.015341938,0.001648625,0.003219712,-0.031745666,0.039133999,-0.029668739,-0.026622664,0.062842462,-0.022248584,-0.008435291,0.009600264,-0.006303015,0.006131646,0.000307778,-0.007101108,-0.056390223,1.132273025,2.457200025,-2.215237064,-2.620083817,-2.587442162,-2.71604171,-1.61091188,-1.54170575,-3.194475992,-0.990976268 -3356,A200S,0.005234763,-0.02556681,-0.005082739,-0.000237133,-0.014845208,0.012398618,0.003561638,0.006907887,0.034065912,-0.04798591,-0.00314771,-0.010515301,0.000349824,-0.013959347,0.013485082,-0.018194692,-0.011495723,1.680490028,3.618873133,-0.492371649,-0.543315247,-0.429975334,-0.618816551,-0.4020019,-0.467749214,-2.68976813,-1.039618749 -3357,A200R,0.004946159,-0.003826467,0.022129448,0.03527823,0.021184161,0.025017957,0.001685341,0.008206977,0.048385631,-0.015124918,0.007471985,0.023881649,0.020377247,0.044994511,0.025561948,0.035558831,0.00680949,1.121916643,2.79062175,-2.107368005,-1.707853683,-2.768899689,-2.106760689,-1.272521233,-2.680804733,-3.268198941,-1.388408908 -3358,A200T,-0.003696762,-0.007576229,0.017188402,0.020583766,-0.004445483,0.027038771,-0.006686813,-0.000706711,0.047373247,-0.020707154,0.005554697,0.025972076,0.008404727,0.032392366,0.008775165,0.008876496,-0.017767462,1.229262094,2.64094817,-1.432600922,-1.500982338,-1.825462746,-1.386390991,-1.029659264,-1.42050927,-2.659399263,-1.610479948 -3359,A200W,-0.044046295,-0.012560905,-0.017588727,0.009104568,-1.124258477,0.057042598,-0.02910655,-0.05898604,0.003531155,-0.029761749,0.00463994,-0.00174889,-0.033428564,0.010881288,0.007327848,-0.920195759,-1.328321195,0.718093897,1.367165078,-6.036016388,-6.064901756,-6.236705299,-6.485004654,-5.147675331,-6.245794899,-6.720253791,-5.111194655 -3360,A200V,-0.007062774,0.050735118,0.020328242,0.025989164,-0.017479696,0.02233301,-0.011824362,-0.002301186,0.021825551,0.084789891,0.016680344,0.053025883,-0.012369399,0.05095116,0.001027168,-0.005128624,-0.029830768,1.543610422,3.106887046,-3.676340923,-3.196195831,-4.759832581,-3.999154259,-2.914144051,-3.512377892,-4.810783426,-2.794806071 -3361,A200Y,-0.021652706,-0.037985166,-0.034170978,-0.024685984,-0.116248878,0.009581237,-0.042611713,-0.000693699,0.11714216,-0.025409548,-0.050560783,-0.02751886,-0.040823095,-0.024286457,-0.025085511,-0.017903685,-0.214594071,1.232115325,2.429077035,-4.867099884,-4.744533501,-5.629223709,-5.517648354,-3.236721313,-5.207372543,-5.581615655,-3.710639922 -3362,S201A,0.058912639,0.075785461,0.035453647,0.011202742,-0.031490122,0.034466881,0.062018142,0.055807135,0.054150194,0.058552512,0.09301841,0.045320039,0.025587254,0.008957839,0.013447645,-0.015205865,-0.047774379,1.136862586,2.473260191,-5.015778911,-4.525545143,-5.794193359,-6.027866684,-3.889876305,-4.841413063,-3.940772615,-0.96982833 -3363,S201C,0.080602776,0.10764683,0.043359389,0.042955041,-0.840956088,0.143920691,0.128008641,0.03319691,0.047132176,0.027955272,0.187338387,0.084618531,0.002100247,-0.018510915,0.104420996,-0.550014685,-1.131897491,0.843778894,1.492708483,-10.68418734,-10.89577136,-11.67805361,-11.63821697,-9.82550769,-9.383387054,-8.622655714,-5.178548529 -3364,S201E,0.048420206,0.008935469,-1.267088602,-2.261866755,-2.764541722,0.096039068,0.075155531,0.021684881,0.042426881,0.020594172,-0.002723235,-1.292488377,-1.241688827,-2.182680679,-2.341052831,-2.933691983,-2.59539146,0.520758176,0.061040861,-8.518540659,-5.967336609,-8.74648597,-11.33289661,-7.82415863,-8.72182547,-5.128325582,-2.179564379 -3365,S201D,-0.006148843,0.029843457,-0.450277439,-2.168001972,-2.588748537,0.005470103,0.001304935,-0.01360262,-0.028970281,0.034047223,0.02563969,-0.355875355,-0.544679523,-2.388735161,-1.947268782,-2.139746465,-3.037750609,1.086714471,0.479627567,-7.512343588,-5.828881813,-6.848253029,-9.755699974,-7.842187416,-7.286695709,-5.30612809,-1.700953039 -3366,S201G,0.035568879,0.057968918,0.015578802,0.002437304,-0.066645769,0.053234026,0.027449603,0.043688154,0.017634112,0.026937261,0.089000575,0.022748163,0.008409441,-0.022269274,0.027143881,-0.063387213,-0.069904324,1.216623114,2.35890501,-7.449653735,-8.414598816,-6.847459137,-8.450563751,-6.298477432,-7.23716954,-5.764700047,-2.667625788 -3367,S201F,0.049190228,0.073449909,0.005042318,-0.956098951,-1.874663113,0.09315016,0.059160091,0.039220364,0.002650112,0.038538416,0.108361402,0.000297645,0.009786991,-0.853830805,-1.058367096,-1.860114614,-1.889211612,2.179448238,1.598394009,-11.8063227,-13.51024082,-13.92246842,-11.48317596,-11.7319626,-8.383765694,-7.689822272,-4.459539285 -3368,S201I,-0.031273503,0.047907902,-0.065810406,-1.671864169,-2.544155728,0.108963508,0.014411825,-0.076958831,0.019731305,-0.001856932,0.097672735,-0.042167276,-0.089453536,-1.9283196,-1.415408738,-2.156452159,-2.931859297,0.908308158,0.674327355,-12.98294311,-13.72494852,-15.29630914,-14.48760004,-10.34980784,-11.05605002,-7.594301749,-3.902665364 -3369,S201H,0.151057406,0.138598553,0.089693922,0.087457043,-0.334359694,-0.051183623,0.018405424,0.283709387,-0.027610986,0.195774005,0.0814231,0.121573545,0.057814298,0.107110138,0.067803948,-0.228312452,-0.440406936,0.840050881,1.710938833,-9.094187946,-10.76593639,-9.384600571,-10.22636851,-7.560330338,-7.533703918,-5.620228354,-2.196514976 -3370,S201K,-0.092811746,-0.009571605,0.03806445,-0.014802606,-1.509409538,0.13352033,-0.022517407,-0.163106085,0.034601543,0.055016747,-0.074159957,0.080747837,-0.004618937,-0.006525528,-0.023079683,-1.25608503,-1.762734046,0.700254982,1.335633859,-10.64617295,-8.505343575,-12.51777921,-13.39937077,-7.897706337,-10.91066483,-6.048756889,-2.108589629 -3371,S201M,0.009987963,0.125748612,0.069701232,0.066017724,-0.147038285,0.043895555,0.048647056,-0.02867113,0.029837753,0.139615226,0.111881997,0.12446441,0.014938053,0.092686285,0.039349162,-0.10118307,-0.192893499,1.118541736,2.212869614,-12.07658529,-12.37099459,-12.22245094,-14.02111259,-9.893419159,-11.87494916,-7.519496413,-3.824881271 -3372,S201L,0.045287467,0.102756799,0.054844124,0.02906642,-1.396292631,0.129539783,0.040121781,0.050453153,0.036773397,0.075733858,0.12977974,0.084705038,0.024983209,0.016383837,0.041749003,-1.139869862,-1.6527154,0.65336427,1.338756994,-11.35795939,-12.32415085,-11.89856492,-14.03701805,-9.584003433,-8.946059715,-6.858910255,-2.348337164 -3373,S201N,-0.071533666,-0.005406604,0.021706694,-0.025106682,-0.239890997,0.029382441,-0.0000887,-0.142978631,0.070576763,-0.088550297,0.07773709,0.029730918,0.013682469,-0.011246778,-0.038966586,-0.131945364,-0.34783663,1.465825263,2.323398534,-6.735959923,-6.675410995,-6.131783165,-9.093244171,-5.93486322,-5.844498062,-5.37557227,-2.619309654 -3374,S201Q,0.033885989,0.088679825,0.038422615,0.04016824,-1.569776964,0.079417324,-0.009216912,0.076988889,0.110109888,0.10731961,0.070040039,0.083457338,-0.006612109,0.113008568,-0.032672089,-1.399383776,-1.740170151,0.435615855,1.312020926,-9.63957339,-8.279954117,-10.93554783,-12.57107229,-7.666596687,-8.74469603,-5.799340962,-1.78087795 -3375,S201P,0.024611212,0.021190739,-0.019472077,-1.613393625,-2.184156114,0.035446489,0.0247691,0.024453324,0.032469592,0.013437682,0.028943795,0.006980343,-0.045924496,-1.578065397,-1.648721852,-2.312989881,-2.055322346,0.646431506,0.696931494,-10.0507757,-9.229124176,-12.16369623,-9.80280497,-9.063842079,-9.994411026,-7.84256926,-4.747873306 -3376,S201R,0.005019381,0.042968997,-0.004749116,-0.01867951,-1.398191684,0.141787874,0.010544136,-0.000505375,-0.00453762,0.004248656,0.081689338,0.005481418,-0.01497965,-0.025375048,-0.011983972,-1.195087573,-1.601295794,0.590299237,1.330515566,-11.56515545,-10.14757697,-12.11717044,-15.22759116,-9.116005898,-11.21743277,-6.59070918,-2.818470642 -3377,S201T,-0.009666123,0.016144154,0.021141023,0.009639763,-0.745591461,0.030912736,0.018662416,-0.037994661,0.002343965,-0.009024187,0.041312494,0.014352998,0.027929047,-0.00453169,0.023811216,-0.524030928,-0.967151994,0.798774203,1.465605422,-5.781961555,-5.82442691,-6.10699894,-7.266625259,-3.982652672,-5.729103996,-5.585314203,-2.800630659 -3378,S201W,0.000336071,0.023022663,-0.070447111,-1.641363864,-2.368502358,0.112515205,0.013499097,-0.012826956,-0.043266869,-0.00496738,0.051012706,-0.030078924,-0.110815297,-1.537154994,-1.745572734,-2.367347544,-2.369657171,0.829888398,0.711370144,-13.02165139,-13.7134221,-13.98080469,-15.27960901,-11.01376413,-11.12065701,-8.00235837,-4.83075208 -3379,S201V,0.018122689,0.048866355,0.04137407,-1.075451783,-1.946646683,0.056253988,0.024981234,0.011264143,0.038062075,0.03518336,0.06254935,0.05305145,0.02969669,-0.862389599,-1.288513966,-2.046370194,-1.846923172,2.129355032,1.513683812,-11.15350388,-10.95374879,-13.63205905,-12.67400446,-8.002326874,-10.50538023,-7.173079853,-2.609197494 -3380,S201Y,0.031201891,0.048717216,0.029395108,-0.18720972,-1.529393499,0.066987247,0.020020949,0.042382833,0.025314572,0.015777993,0.081656438,0.06843177,-0.009641554,-0.137779257,-0.236640182,-1.455458578,-1.60332842,1.032613574,1.355593448,-10.9954052,-13.73526484,-12.74059484,-10.57682082,-9.244829674,-8.679515816,-6.862942652,-2.287928449 -3381,R202A,0.01412703,-0.000811593,-0.005240613,-0.02549675,-0.089946034,0.040802496,-0.003522963,0.031777022,0.007204341,-0.004250396,0.00262721,0.004093616,-0.014574841,-0.031601969,-0.019391531,-0.093816672,-0.086075396,1.25470461,2.245114357,-3.143709715,-3.393623505,-2.470641785,-3.194128731,-3.226112602,-3.434041954,-3.596221067,-2.359906498 -3382,R202C,0.006926441,-0.050696322,0.000581859,-0.010223511,-0.408126146,0.058954521,-0.0018845,0.015737382,0.07982787,-0.018175298,-0.083217346,-0.035212168,0.036375886,-0.006206908,-0.014240113,-0.253535791,-0.5627165,1.416430235,2.051316254,-5.566402193,-4.96781855,-4.864420586,-8.126653206,-5.075690346,-4.797428276,-4.566229375,-1.512302667 -3383,R202E,-0.0154208,0.054178754,0.035395489,0.055632887,-0.795980403,0.081401893,0.023731557,-0.054573156,0.016449105,0.024734857,0.083622651,0.007460966,0.063330012,0.03326819,0.077997584,-0.516176957,-1.075783849,0.683549567,1.430067376,-5.125272864,-4.620369392,-6.077567047,-5.316691277,-4.090544502,-5.521192101,-5.687659357,-5.009680595 -3384,R202D,-0.030420987,0.018399312,-0.267550214,-1.778601346,-2.503355296,0.060336771,0.004416127,-0.065258101,-0.036788382,0.034709447,0.002089177,-0.166824492,-0.368275936,-1.741523432,-1.815679259,-2.660499191,-2.346211401,1.010177622,0.70230544,-6.606283138,-4.841026527,-7.010227173,-7.204793289,-6.05703141,-7.918337288,-6.190203611,-2.690020938 -3385,R202G,0.011607758,0.002257947,-0.004669171,0.024751007,-0.6735225,0.077376177,0.017229799,0.005985717,-0.005079558,0.001114177,0.003401717,-0.013861317,0.004522976,-0.004447073,0.053949086,-0.505861574,-0.841183425,1.183847163,1.634563121,-4.948853743,-3.646416641,-5.11080011,-5.81868956,-4.664818657,-5.503543747,-4.912314148,-3.200783654 -3386,R202F,-0.022245764,-0.057054902,0.031047635,-1.334794474,-2.154417167,0.019867033,0.003350029,-0.047841556,-0.055316219,-0.042482571,-0.071627233,0.046700584,0.015394685,-1.184921314,-1.484667634,-1.876098992,-2.432735341,2.657613778,1.878963964,-9.169605334,-7.242079353,-7.613571587,-12.53218848,-8.225723801,-10.23446345,-6.106737802,-4.441405817 -3387,R202I,-0.043907101,0.093036045,-0.013478811,0.12176351,-1.284960855,0.097353712,0.00643359,-0.094247792,-0.036102293,0.150102866,0.035969223,0.120219857,-0.147177479,0.137654398,0.105872621,-0.847585835,-1.722335875,0.420078286,1.338069326,-7.31711071,-6.522624886,-8.191107018,-8.09058799,-6.342393509,-7.438840149,-6.846519519,-5.937942989 -3388,R202H,-0.02993092,0.002946586,-0.004596067,0.037142847,-1.331543416,0.04904212,0.058164222,-0.118026061,0.013199948,-0.032721776,0.038614947,-0.015418449,0.006226316,0.033113832,0.041171862,-1.155349213,-1.507737619,0.666225592,1.338910085,-5.483851369,-4.111887909,-5.52233046,-6.865654343,-5.221072975,-5.698311157,-5.838667847,-3.226056487 -3389,R202K,-0.096902314,-0.051238245,-0.021766923,0.015281344,-0.042276035,0.02085543,-0.018707429,-0.175097198,0.011375178,-0.051009294,-0.051467196,-0.077754846,0.034221001,-0.039212684,0.069775372,-0.024038404,-0.060513665,1.294167229,2.486212468,-2.422831239,-1.108991119,-3.492876663,-3.941651543,-1.793736923,-1.776899948,-3.75523613,-2.27604613 -3390,R202M,-0.044682358,-0.030387697,-0.032367162,-0.013713747,-0.858495436,0.066653431,-0.043191797,-0.046172919,-0.06049033,-0.000389975,-0.060385418,-0.030751809,-0.033982515,0.007771079,-0.035198572,-0.699078097,-1.017912774,0.659798511,1.388888063,-7.316168536,-6.846751862,-7.925272644,-8.391896332,-6.735524017,-6.681397827,-7.172639259,-5.824200377 -3391,R202L,-0.021061743,-0.014458604,-0.008090437,-0.00638522,-1.542524433,0.065869511,0.014186502,-0.056309988,-0.024472485,-0.024889261,-0.004027947,-0.054630085,0.038449212,-0.065750314,0.052979875,-1.536524483,-1.548524382,0.740094671,1.322408661,-4.978351216,-5.086270103,-5.26750959,-6.302969719,-3.755172295,-4.479834373,-4.893438468,-3.618671373 -3392,R202N,-0.071425063,0.033159054,-0.026066332,-0.032485634,-1.125712004,0.070044428,0.004014958,-0.146865084,0.020111942,0.040355628,0.025962479,-0.051371691,-0.000760972,-0.097031576,0.032060309,-1.025953446,-1.225470562,1.127493959,1.435877865,-6.624979776,-4.916043961,-7.356681992,-8.128961685,-5.716518875,-7.006692368,-5.842238563,-3.77373789 -3393,R202Q,-0.051652413,0.015231446,0.012189075,0.06943881,0.057127195,0.060328116,-0.001253854,-0.102050971,-0.001468039,0.030513691,-0.0000508,0.055108041,-0.030729892,0.09684502,0.0420326,0.067910187,0.046344202,1.145901112,2.997685945,-1.007815419,-0.904976227,-1.662644363,-0.877229774,-0.780896545,-0.813330185,-1.251869208,-2.145239083 -3394,R202P,-0.023292233,-0.12355947,-1.397328646,-2.156212099,-2.418157231,0.068733222,-0.012480873,-0.034103593,-0.019879952,-0.067160867,-0.179958073,-1.460639711,-1.334017581,-2.258205676,-2.054218521,-2.411264641,-2.425049821,1.065967675,0.087104787,-8.711130405,-7.518736511,-8.668003113,-9.953651321,-8.313440643,-9.101820435,-7.357731992,-6.239192358 -3395,R202S,0.003758859,-0.007672941,-0.024271495,0.028694031,-0.014030269,-0.008757108,-0.021484749,0.029002467,-0.01161889,0.013851291,-0.029197173,0.003710736,-0.052253725,0.027214171,0.03017389,0.032641269,-0.060701806,1.255488204,2.703136383,-3.781878111,-3.601074783,-3.083462425,-5.03497628,-3.562832382,-3.627044685,-4.265002482,-1.328426158 -3396,R202T,0.050548777,0.005683138,0.020885276,0.046270422,0.00892554,-0.017228356,0.028174107,0.072923447,0.0006223,0.025754604,-0.014388328,0.030247961,0.011522591,0.069065661,0.023475182,-0.001861009,0.019712088,1.16690635,2.709238972,-4.164589081,-4.599557068,-4.254107552,-5.118462105,-3.998667336,-2.852151344,-3.917276668,-1.290255895 -3397,R202W,-0.013977276,0.005665777,0.022085437,-1.296770303,-1.819953653,0.064905163,-0.001425075,-0.026529476,-0.016357345,-0.014804226,0.026135779,-0.039763359,0.083934232,-1.232345964,-1.361194641,-1.943045781,-1.696861524,2.786717393,1.944826365,-9.572027321,-7.800009033,-8.90658329,-11.88532306,-8.834569626,-10.4336516,-7.96267538,-6.646083331 -3398,R202V,0.051220643,0.025211981,0.027117562,0.064059265,-0.350332115,0.045431757,0.056369128,0.046072157,-0.020021501,-0.005074795,0.055498756,0.023632812,0.030602311,0.036729349,0.09138918,-0.293640805,-0.407023424,1.542395447,2.114257004,-6.368198099,-6.174617279,-7.338235451,-6.935490776,-5.815925377,-5.576721611,-6.061554855,-5.154049418 -3399,R202Y,-0.035421283,-0.072770836,-0.015233299,-0.115584596,-1.688556108,0.041978715,0.035309901,-0.106152466,-0.035929025,-0.08203182,-0.063509852,-0.058960567,0.028493969,-0.096448649,-0.134720542,-1.954229948,-1.422882268,1.022293024,1.312197351,-9.124646787,-6.233295227,-8.959063087,-12.34860015,-8.319675156,-9.762600311,-6.397831888,-3.317259661 -3400,Q203A,0.009047373,-0.085216323,-0.06072866,-0.054389064,-0.133863722,0.033598062,-0.003634285,0.02172903,-0.007569052,-0.101486249,-0.068946396,-0.094744567,-0.026712752,-0.11475513,0.005977002,-0.177008959,-0.090718485,1.493593377,2.194152543,-0.891061499,-1.131567566,-0.691809669,-0.421077614,-0.382782982,-1.828069664,-2.817035642,0.932136052 -3401,Q203C,-0.013707403,-0.130153166,-0.082641422,-0.074973065,-0.363158022,0.003662383,-0.018307791,-0.009107015,0.062191046,-0.155197969,-0.105108363,-0.198538678,0.033255834,-0.188381211,0.038435082,-0.380796338,-0.345519706,1.943210211,2.274588303,-5.966348708,-6.534026123,-6.025339577,-5.377712235,-5.32257222,-6.572093384,-7.118625798,-4.394582485 -3402,Q203E,-0.02997642,-0.079687865,-0.080524006,-0.06036529,-0.111883842,0.045276058,-0.036334364,-0.023618475,0.034983566,-0.053542851,-0.105832878,-0.110701821,-0.050346191,-0.118777808,-0.001952772,-0.124756862,-0.099010822,1.506535559,2.276828753,-1.003602013,-1.036028091,-1.481996605,-0.682539375,-0.219239693,-1.598206299,-3.183675062,0.658194204 -3403,Q203D,0.080964106,-0.042763964,-0.02043459,-0.031599992,-0.137649048,0.045961942,0.131839123,0.030089088,-0.008348654,-0.108022985,0.022495058,-0.097488314,0.056619135,-0.088460669,0.025260685,-0.21394192,-0.061356175,1.462352372,2.102074146,-1.799307455,-2.019856232,-2.229813545,-1.52509304,-1.051295441,-2.170479019,-3.713644791,0.574432036 -3404,Q203G,0.036486837,-0.054660443,-0.035741373,-0.018183958,-0.131112702,0.064790188,0.030634425,0.042339248,-0.029020185,-0.078037111,-0.031283774,-0.082384597,0.010901851,-0.073290164,0.036922248,-0.163649004,-0.0985764,1.184961321,1.959597826,-3.170589035,-3.94040535,-2.758094017,-2.669244461,-2.548363487,-3.93683786,-4.520227665,-1.319534216 -3405,Q203F,0.050775695,0.057530164,0.058192094,0.149591527,-0.636254504,0.127188514,0.05996154,0.04158985,-0.161438857,0.127578833,-0.012518505,-0.032898229,0.149282417,0.109068257,0.190114796,-0.535017581,-0.737491426,0.574247118,1.399454783,-6.233446756,-6.736341515,-6.103628098,-6.073323296,-4.997184792,-7.256756081,-6.872597431,-4.431291731 -3406,Q203I,0.033669049,-0.150967654,-0.098661745,-0.091308999,-0.143453602,0.083693169,0.021776978,0.045561119,-0.041158311,-0.223818342,-0.078116965,-0.231767077,0.034443588,-0.170242489,-0.012375509,-0.244324549,-0.042582655,1.661575686,2.183431724,-4.250835226,-4.97158136,-4.244836739,-4.478042816,-3.433714661,-4.126000557,-5.24660358,-3.016086192 -3407,Q203H,0.143710879,-0.040920946,-0.049029882,-0.020392405,-0.104448934,-0.012674969,0.141499942,0.145921816,0.006565066,-0.143527382,0.061685491,-0.181579989,0.083520226,-0.122937149,0.08215234,-0.227859472,0.018961604,1.82105828,2.366708078,-3.055767175,-4.264850128,-2.811855621,-2.532133087,-2.351622353,-3.318374687,-4.773509707,-2.074518811 -3408,Q203K,0.074298141,-0.118643304,-0.012686892,-0.021654339,-0.062261928,-0.043195069,0.053122115,0.095474167,0.010777712,-0.208361391,-0.028925217,-0.098292563,0.07291878,-0.067150604,0.023841927,-0.088274745,-0.036249111,1.23689761,2.201551701,-1.064063065,-1.548339577,-0.986165359,-0.822657669,-0.818102448,-1.14505027,-2.543776781,-0.338444146 -3409,Q203M,0.104041635,-0.101423856,0.012983266,-0.0000521,-0.063881637,-0.044808458,0.084320886,0.123762384,-0.011426431,-0.066096066,-0.136751645,-0.186490494,0.212457025,-0.104792162,0.104687865,-0.093492728,-0.034270545,1.461312939,2.305370451,-4.9914326,-5.667575348,-4.797605606,-5.006145424,-4.248336838,-5.237499786,-5.779285241,-3.772185291 -3410,Q203L,0.076733229,-0.019976816,-0.040596634,-0.012936269,-0.16289009,0.056638306,0.077877896,0.075588562,-0.013868167,-0.042928201,0.002974569,-0.085767511,0.004574243,-0.087221597,0.06134906,-0.215131689,-0.11064849,1.806083444,2.414225014,-3.093569086,-4.157415283,-2.873141525,-3.248852379,-2.163959915,-3.024476326,-4.965731275,-1.687776709 -3411,Q203N,-0.025825348,-0.101093594,-0.137055663,-0.032697742,-0.171366942,-0.02901663,0.034154276,-0.085804972,-0.097281544,-0.042928201,-0.159258986,-0.234038893,-0.040072433,-0.047009061,-0.018386422,-0.171665996,-0.171067888,1.441922423,2.16962819,-2.46831196,-3.403796944,-2.703369385,-2.865697273,-1.430222397,-1.938473801,-4.05033993,-1.015616292 -3412,Q203P,0.033892855,-0.066447601,-0.8554704,-2.029098576,-3.002803861,0.065592161,0.036041841,0.031743868,-0.015156833,-0.123412189,-0.009483013,-1.00036777,-0.71057303,-2.041458198,-2.016738954,-2.733961023,-3.271646699,2.202035548,0.8773569,-5.781249252,-6.24758445,-5.815714127,-5.790782326,-5.007389862,-6.044775497,-7.283458106,-4.435527223 -3413,Q203S,0.027661214,-0.081439249,-0.059361664,-0.042615,-0.125549632,0.082725732,0.024483148,0.03083928,0.036195813,-0.087182804,-0.075695693,-0.112288488,-0.006434839,-0.101622115,0.016392115,-0.176011238,-0.075088025,1.61032494,2.277288853,-2.337544208,-3.230764191,-2.30539698,-1.993581383,-1.710747841,-2.447230644,-4.209973258,-0.893976655 -3414,Q203R,0.047367775,-0.058564478,-0.040398525,-0.01271324,-0.093200959,0.028179235,0.053573617,0.041161932,0.009154382,-0.089068291,-0.028060664,-0.080336694,-0.000460355,-0.080521078,0.055094598,-0.130930249,-0.055471668,1.515423174,2.322853491,-1.240930949,-1.769098618,-0.943542236,-0.841148483,-0.944216743,-1.706648666,-2.073687162,-0.14894945 -3415,Q203T,0.016846408,-0.096390908,-0.061456976,-0.036453177,-0.08307937,0.065000308,0.002246743,0.031446073,0.022963702,-0.098486401,-0.094295414,-0.127135989,0.004222037,-0.082686555,0.009780202,-0.141026881,-0.025131858,1.473926935,2.233998799,-2.203119624,-2.575669037,-2.314930153,-1.735564117,-1.900156723,-2.489278091,-3.804767317,-0.728387932 -3416,Q203W,0.017704225,-0.093253845,-0.046018769,-0.026184829,-0.56026314,0.072701963,0.013263212,0.022145237,-0.069141378,-0.100766478,-0.085741211,-0.122836911,0.030799374,-0.109730532,0.057360874,-0.422964831,-0.697561449,1.795143148,2.143910843,-6.174567584,-6.76061937,-6.009993065,-5.58639698,-5.584800995,-6.931027512,-6.556441515,-4.693252337 -3417,Q203V,0.045013014,-0.020803282,-0.022407666,-0.019157165,-0.13953731,0.030298034,0.050029846,0.039996181,-0.008545372,-0.016748525,-0.024858039,-0.066694601,0.02187927,-0.073341203,0.035026874,-0.155023727,-0.124050893,1.474434788,2.227591337,-3.972264169,-4.522452782,-3.916110832,-3.894717445,-3.337533607,-4.19050618,-4.717166704,-2.563354422 -3418,Q203Y,0.005231051,-0.167024505,-0.025025798,-0.042903346,-0.32455408,0.076706627,-0.040617851,0.051079953,-0.073642058,-0.189056236,-0.144992774,-0.111574775,0.06152318,-0.132139639,0.046332947,-0.359483467,-0.289624692,1.966092359,2.348822776,-5.962945793,-6.675343163,-5.88945314,-5.817266281,-4.968796249,-6.463870132,-7.136570454,-4.399146897 -3419,Q204A,-0.009730887,-0.024993151,-0.049539253,-0.034237914,-0.102016433,0.032298903,0.023037468,-0.042499242,-0.040804684,-0.077199885,0.027213584,-0.097871906,-0.001206599,-0.079614709,0.011138882,-0.142703424,-0.061329441,1.51423015,2.284770403,-6.928385054,-5.896941315,-7.806191856,-6.556190086,-8.14611496,-6.236487053,-6.995307368,-1.389158577 -3420,Q204C,-0.020765872,0.029843336,-0.012705597,0.076884177,-0.043050656,0.050648317,-0.007256692,-0.034275052,-0.055255463,0.059440562,0.00024611,0.023202255,-0.048613449,0.130708091,0.023060263,0.02928292,-0.115384231,1.063985464,2.807512953,-10.26420583,-9.689733711,-10.22784941,-9.631563438,-12.12607321,-9.645809364,-8.537906429,-5.379497447 -3421,Q204E,-0.032467208,-0.005834331,-0.033789291,-0.045914631,-0.049271281,-0.01833168,0.00912238,-0.074056796,-0.074966759,-0.02538629,0.013717629,-0.04742465,-0.020153932,-0.0444736,-0.047355662,-0.067357532,-0.03118503,1.288020487,2.315570624,-4.793254344,-4.273599579,-6.029192978,-4.62771769,-5.415277351,-3.620484123,-6.621755223,-0.828970683 -3422,Q204D,-0.072188449,0.032241165,-0.009304158,-0.008682049,-0.441077459,0.07291431,-0.026080016,-0.118296881,-0.074933015,-0.025450012,0.089932341,-0.009273544,-0.009334772,-0.024741816,0.007377718,-0.313380434,-0.568774484,1.142910796,1.76653607,-9.718823666,-9.903390457,-11.3989586,-7.914471497,-12.77802245,-6.599275322,-7.317098519,-2.755504804 -3423,Q204G,-0.037548672,-0.028265931,-0.035292868,-0.177222968,-1.786870088,0.10295553,-0.004941922,-0.070155421,-0.112411918,-0.056335466,-0.000196396,-0.070790954,0.000205218,-0.156718257,-0.197727679,-1.673550461,-1.900189714,1.154406569,1.350629763,-10.35932461,-9.756956596,-10.26896438,-10.12925534,-11.86313744,-9.778309303,-7.967409284,-4.219445045 -3424,Q204F,-0.006789703,0.026093242,-0.051287222,0.01939235,-0.770665464,0.089031146,-0.000523309,-0.013056097,-0.129343457,-0.036907033,0.089093516,-0.05473879,-0.047835654,-0.012382908,0.051167608,-0.592134035,-0.949196892,0.965988554,1.490980685,-8.206986012,-7.236257515,-7.038316292,-5.875154564,-10.38010383,-10.50509786,-6.15695264,-0.771724835 -3425,Q204I,0.041960461,0.006712298,0.021066124,0.042673057,0.012872343,0.050409503,0.083771139,0.000149783,-0.077982089,0.061396218,-0.047971623,-0.014086461,0.056218708,0.043905486,0.041440628,-0.024057198,0.049801883,1.299156972,2.629359607,-6.326507518,-5.364922058,-7.192080353,-6.309971375,-8.456743675,-4.308820129,-4.908510103,-1.822933351 -3426,Q204H,-0.026674787,-0.001076688,-0.043184657,0.026326248,-0.08535206,-0.012439457,-0.020613442,-0.032736132,-0.065528893,-0.017685659,0.015532284,-0.008474308,-0.077895006,0.045499927,0.007152569,-0.044454435,-0.126249684,1.212521533,2.547673376,-5.323970877,-5.303025703,-4.649339287,-3.836031944,-5.896350845,-6.935106606,-5.174337541,-2.627184904 -3427,Q204K,0.006345465,-0.039110271,-0.072722789,-0.028403328,-0.271795292,-0.090846588,0.00156968,0.011121249,-0.134552449,-0.137774199,0.059553658,-0.035164417,-0.110281161,-0.05561704,-0.001189616,-0.254785719,-0.288804864,1.449057858,2.03521767,-3.149801241,-3.731339188,-2.358207733,-3.491384727,-3.834167542,-2.333907013,-3.846817603,-1.612371369 -3428,Q204M,0.013628903,-0.021238913,0.000480905,-0.049963987,-0.027101503,-0.03954068,0.030497981,-0.003240175,-0.002857593,-0.053638474,0.011160648,-0.020586531,0.02154834,-0.04971548,-0.050212494,-0.030833844,-0.023369161,1.450314855,2.561284008,-6.387218326,-5.610242935,-7.587726112,-5.772013199,-7.918727463,-5.04738192,-6.151981163,-2.065276824 -3429,Q204L,0.007422384,0.004814295,-0.000320769,0.021258806,0.004851927,0.002844071,0.01424432,0.000600448,-0.060463376,-0.07468988,0.08431847,-0.022114314,0.021472776,0.006415923,0.036101689,-0.041269882,0.050973736,1.269526613,2.481517741,-4.711900244,-4.036818321,-5.244483826,-4.175625587,-5.913547356,-4.189026131,-3.622523234,-0.217411067 -3430,Q204N,-0.02479313,-0.027897848,0.035344717,0.071439702,-0.08281981,0.043573272,0.069535032,-0.119121291,-0.075885732,-0.001191481,-0.054604214,0.087150176,-0.016460742,0.098311529,0.044567875,-0.052779095,-0.112860525,1.244192204,2.483465343,-7.790969315,-8.371457451,-7.187158455,-7.62318074,-8.955768379,-6.817281548,-7.789989527,-4.281937966 -3431,Q204P,-0.031377557,-0.001233738,-0.188287951,-1.734230786,-2.3246163,0.143612099,0.014259436,-0.07701455,-0.110958578,-0.039322457,0.036854982,-0.196021898,-0.180554004,-1.666191696,-1.802269876,-2.151656955,-2.497575645,1.261551642,0.745807603,-9.012237086,-8.522665092,-9.101436501,-7.67965802,-10.08138094,-9.676044884,-7.314275267,-3.625557701 -3432,Q204S,-0.020187171,0.001088683,-0.01489269,0.036134282,-0.186846148,0.012153545,-0.000267164,-0.040107178,-0.086292106,-0.037127291,0.039304656,-0.008168789,-0.02161659,0.049350468,0.022918095,-0.160845207,-0.212847088,1.310114585,2.176296874,-7.599155696,-6.960952103,-7.979813316,-7.077667099,-9.411826927,-6.565519035,-7.483974931,-3.277965501 -3433,Q204R,-0.021702945,-0.00139804,-0.064459337,-0.013331497,-0.115500466,0.084304336,0.011473049,-0.054878938,-0.059994199,-0.05537413,0.052578051,-0.097961574,-0.030957099,-0.032208554,0.00554556,-0.118280942,-0.11271999,1.404742944,2.264955788,-3.980964052,-4.157758018,-3.682695976,-3.281483986,-4.705201057,-4.077681221,-4.520942915,-0.138971398 -3434,Q204T,-0.011209562,-0.009830137,-0.070173495,-0.052257522,-0.056559811,-0.034811822,0.005040955,-0.027460078,-0.04017235,-0.034790038,0.015129764,-0.098250134,-0.042096856,-0.026179085,-0.078335959,-0.077834206,-0.035285416,1.223787824,2.207505222,-5.288090616,-4.037604362,-6.353929657,-5.75799514,-6.227979462,-4.062944458,-4.794205527,-1.840653195 -3435,Q204W,-0.028799862,-0.042011687,-0.041096952,-0.03338423,-1.247783737,0.114905956,0.021776474,-0.079376198,-0.154134722,-0.063901217,-0.020122157,-0.090569835,0.008375931,-0.04984088,-0.01692758,-0.993601002,-1.501966472,1.392301564,1.544910084,-8.559796611,-8.915647606,-7.728343636,-5.590786774,-10.61903686,-9.945168182,-7.100855583,-2.406676212 -3436,Q204V,0.005264583,0.021071643,-0.029116932,0.008258363,-0.041599533,-0.014870648,0.035987305,-0.025458139,-0.086107043,-0.005590092,0.047733378,-0.039594362,-0.018639501,0.013785725,0.002731001,-0.033584791,-0.049614274,1.271114357,2.630115111,-6.961271057,-5.660403587,-8.026576248,-6.411172775,-9.208332321,-5.499870354,-6.137435554,-1.623707938 -3437,Q204Y,0.079247618,-0.014098209,-0.0087085,-0.009405432,-0.310308743,0.008972584,0.116684812,0.041810423,-0.064618127,-0.174903038,0.14670662,-0.080519597,0.063102598,-0.032792513,0.01398165,-0.414486562,-0.206130924,1.262092801,1.737657267,-7.758536011,-7.373331421,-5.261333893,-6.908965324,-9.320110069,-9.928939346,-6.29015821,-1.889148187 -3438,L205A,0.019851063,-0.015396981,-0.034639964,-1.658049225,-2.461863376,0.04322961,-0.010479932,0.050182057,-0.069597491,-0.013703185,-0.017090776,-0.06811091,-0.001169017,-1.670185323,-1.645913126,-2.333458432,-2.59026832,0.936613229,0.706922305,-12.20451401,-12.36238978,-12.6526627,-10.13373679,-9.627166245,-16.24661452,-6.090057058,-2.594446156 -3439,L205C,-0.019895716,-0.000569618,-0.054033073,-1.836800564,-2.875775708,0.003212922,-0.05668269,0.016891258,-0.030231242,0.024367814,-0.025507049,-0.046141259,-0.061924887,-1.8532546,-1.820346527,-2.885743566,-2.865807849,0.66464182,0.673460125,-11.4146319,-13.57925574,-11.01678369,-10.85272196,-8.69694928,-12.92744884,-8.043977132,-5.2450627 -3440,L205E,0.006694573,0.031572173,-1.108244013,-2.325716998,-2.785510896,0.017666524,-0.001568135,0.014957281,-0.06349039,0.062592862,0.000551484,-1.172208356,-1.04427967,-2.173896361,-2.477537635,-2.650082827,-2.920938965,0.569892665,0.08209052,-14.78454096,-15.90706487,-14.51110901,-13.48524332,-12.62438112,-17.39490649,-10.27267504,-10.18488361 -3441,L205D,0.057195529,-1.082538258,-2.378696387,-2.665103682,-2.726957571,0.025724288,0.065306561,0.049084497,-0.005336976,-1.263456643,-0.901619873,-2.42047082,-2.336921953,-2.405125486,-2.925081878,-2.483371943,-2.970543199,0.297380981,-0.775698183,-14.92006315,-16.33820818,-14.68664388,-13.79396,-12.1979035,-17.58360016,-10.27267504,-10.18488361 -3442,L205G,-0.004659702,-0.614059644,-2.070984327,-2.479275907,-2.949099702,0.02923512,-0.003864837,-0.005454567,0.011988781,-0.594613098,-0.633506189,-2.095738725,-2.046229928,-2.36918893,-2.589362883,-2.661315207,-3.236884196,1.09562683,-0.303195952,-12.82780751,-14.37696815,-12.72808591,-11.78300147,-10.88779417,-14.36318786,-7.685140826,-4.968338894 -3443,L205F,-0.032178969,-0.031868469,-0.024513032,-0.120973011,-1.871064387,0.035709132,-0.015095085,-0.049262853,-0.066830476,-0.02863341,-0.035103527,-0.073118109,0.024092046,-0.197109332,-0.044836689,-1.471418129,-2.270710644,1.312322062,1.403767805,-5.833958481,-5.695153603,-6.216447617,-5.27031443,-5.455759476,-6.532117279,-5.006244164,-2.879872603 -3444,L205I,0.001416933,0.032587775,-0.015563045,0.037772743,-0.249558421,0.020642222,-0.022556787,0.025390653,-0.005490059,0.048357743,0.016817806,-0.041709645,0.010583556,0.009847862,0.065697623,-0.189220765,-0.309896076,1.360517876,2.106268779,-5.377160211,-5.350344437,-5.300337196,-6.325852158,-5.100272621,-4.808994644,-5.263339158,-2.010209142 -3445,L205H,0.006892927,-0.365777736,-1.938760469,-2.60437136,-2.728694618,0.007983501,-0.016132122,0.029917975,-0.015007204,-0.358133774,-0.373421698,-2.214117956,-1.663402981,-2.499802618,-2.708940102,-2.702987811,-2.754401424,0.757295667,-0.338846108,-13.85371351,-14.50213554,-13.42364077,-13.16564353,-11.45053887,-16.72660886,-10.27267504,-10.18488361 -3446,L205K,0.00231367,-1.280676373,-2.182737908,-2.531614572,-2.59346846,0.079158584,0.02612741,-0.021500071,-0.085210466,-1.7038005,-0.857552246,-2.161844673,-2.203631142,-2.447529335,-2.615699808,-2.525775791,-2.661161129,-0.067019789,-1.063933208,-14.21506142,-15.45180968,-14.16354399,-13.04528584,-11.4736339,-16.94103371,-10.21800695,-9.932737047 -3447,L205M,0.010868094,-0.019381352,-0.020774304,-0.036893618,-0.083827633,-0.006327418,-0.000503402,0.022239589,-0.086459209,-0.065967239,0.027204536,-0.089442508,0.0478939,-0.014511484,-0.059275751,-0.089982887,-0.077672378,1.360942417,2.332839163,-6.192726794,-6.399631874,-4.48518425,-5.423384911,-7.004078995,-7.651353943,-5.43290365,-1.160793435 -3448,L205N,-0.03353555,-0.313474985,-1.813753097,-2.313144758,-2.764074272,0.022149444,-0.002719758,-0.064351341,-0.107829808,-0.305544755,-0.321405215,-1.967708911,-1.659797282,-2.253393573,-2.372895943,-2.632670025,-2.895478519,1.085758702,-0.107206493,-14.18454103,-16.19117523,-13.21128432,-13.359175,-12.20116688,-15.95990372,-10.27267504,-10.18488361 -3449,L205Q,0.022047673,0.107340099,-1.024994801,-2.17490146,-2.736755349,0.025358406,0.005449956,0.03864539,-0.01779787,0.168251663,0.046428534,-0.975534249,-1.074455352,-2.26121891,-2.088584009,-2.816586622,-2.656924076,0.48572669,0.098547005,-13.12990704,-14.51053258,-12.60570457,-12.00533751,-10.48405785,-16.04390269,-9.339040551,-7.654565728 -3450,L205P,-0.000986359,-1.08842056,-2.155942997,-2.368604129,-2.968101119,0.041800188,-0.00689488,0.004922162,0.009150973,-1.268461663,-0.908379457,-2.247406015,-2.064479978,-2.307311634,-2.429896623,-2.807631779,-3.128570458,0.095305527,-0.774392435,-12.94505789,-14.50835458,-13.04197619,-12.28465415,-10.63440548,-14.25589904,-8.205569201,-6.298473446 -3451,L205S,-0.038651277,-0.132195601,-1.465064321,-2.336847929,-3.040917185,0.014375639,-0.039953762,-0.037348791,-0.032442201,-0.070943296,-0.193447905,-1.547736905,-1.382391736,-2.519802444,-2.153893413,-2.966025686,-3.115808684,0.788923095,0.034129325,-14.07678772,-15.98993616,-13.62148308,-13.20527725,-12.21245905,-15.35478309,-9.613457214,-7.633653738 -3452,L205R,-0.024106147,-1.231224138,-2.217487887,-2.2882133,-3.216264069,0.056269062,-0.028128809,-0.020083484,-0.003659815,-1.3946145,-1.067833775,-2.250598681,-2.184377092,-2.059162088,-2.517264512,-2.739468536,-3.693059602,-0.125109224,-0.872408836,-14.32629773,-15.8349936,-13.70488641,-13.23032948,-11.46053732,-17.40074187,-10.27267504,-10.18488361 -3453,L205T,-0.026679117,0.015355856,-0.107506054,-1.814054746,-2.364069586,0.025617056,-0.040602574,-0.01275566,-0.042783105,0.046173525,-0.015461813,-0.074705127,-0.14030698,-1.766636229,-1.861473263,-2.462182644,-2.265956528,0.831504509,0.690175068,-12.8851837,-14.61248753,-13.4027925,-10.50753795,-11.19986922,-14.70323128,-7.872359776,-5.400813818 -3454,L205W,0.01021667,0.011621029,-0.002093553,-1.460246231,-2.016528177,0.007436162,0.00771002,0.01272332,-0.046688211,0.003853154,0.019388903,-0.05220217,0.048015064,-1.291182134,-1.629310327,-2.122756257,-1.910300096,2.349978198,1.516787073,-10.2090282,-10.0729953,-9.377304054,-9.86591153,-8.791057693,-12.93787243,-7.710166673,-6.29847324 -3455,L205V,-0.0332432,-0.031755667,-0.005024541,-0.016427207,-1.66022784,0.025295441,-0.023272667,-0.043213732,-0.068674316,-0.046293803,-0.017217531,-0.033196775,0.023147693,-0.009280787,-0.023573627,-1.567239099,-1.75321658,0.612876198,1.312323321,-8.101881889,-8.814419838,-8.375038361,-7.816889626,-7.402509628,-8.100551994,-5.565181939,-2.22406891 -3456,L205Y,-0.016686586,-0.0447879,-1.180967069,-2.772704446,-2.834558335,0.077026721,0.024838463,-0.058211634,-0.102939233,-0.055303054,-0.034272746,-1.124362061,-1.237572077,-2.665319228,-2.880089664,-2.743565684,-2.925550986,0.884138948,0.123134016,-9.771314713,-10.02374464,-9.755913681,-9.328292686,-8.24957164,-11.49905091,-7.396978088,-5.64831544 -3457,I206A,0.050049516,-0.021650217,0.003051636,-0.011995618,-0.095585022,-0.035289523,0.058581323,0.041517708,0.03452531,0.022244576,-0.065545009,-0.045044735,0.051148007,-0.002665701,-0.021325535,-0.166403798,-0.024766245,1.604836722,2.37359826,-1.947537602,-1.946796082,-2.635975182,-0.774746559,-1.498135376,-2.882034813,-2.419399341,-1.314093931 -3458,I206C,0.056276688,-0.016204476,0.02971354,0.00803283,-0.120373889,-0.059680889,0.045955633,0.066597743,0.06031025,0.025042907,-0.057451859,-0.021714568,0.081141648,0.011353924,0.004711735,-0.172991332,-0.067756445,1.375932068,2.17049496,-5.749617516,-4.805214844,-4.552616791,-6.325218597,-6.14028685,-6.924750496,-5.558427296,-3.853174189 -3459,I206E,0.005228392,-0.055838723,0.000714687,-0.048548315,-0.468149603,0.080354654,-0.00164332,0.012100104,0.048135572,-0.007976633,-0.103700813,-0.066373716,0.067803089,-0.044947639,-0.05214899,-0.43787154,-0.498427666,1.448778451,1.856801319,-1.804376979,-1.763144585,-1.836326523,-1.464487595,-0.900129005,-3.057797188,-2.866695879,-1.321184706 -3460,I206D,-0.072856554,-0.077987448,-0.036688185,-1.482460182,-2.292964037,0.009224872,-0.092499066,-0.053214042,0.049161441,0.022692186,-0.178667081,-0.031897236,-0.041479133,-1.146509665,-1.818410699,-2.430204099,-2.155723974,0.809928908,0.74630745,-4.533380737,-4.468248474,-4.0825438,-3.473201645,-4.429447784,-6.213461983,-4.10272646,-2.910718723 -3461,I206G,0.010808238,-0.034531354,-0.027168147,-0.042055194,-0.507712402,0.024852141,0.020925049,0.000691427,0.050784152,0.027436265,-0.096498972,-0.047684656,-0.006651638,-0.012505477,-0.07160491,-0.448896081,-0.566528723,1.993169563,2.308482883,-4.415394609,-4.051716248,-4.246923866,-4.053126984,-4.165706337,-5.559499611,-3.590996891,-3.247801969 -3462,I206F,0.029917628,-0.068100536,-0.100712189,-0.055906262,-0.115699014,0.093250674,0.080880894,-0.021045639,0.043465694,-0.055184445,-0.081016627,-0.13020727,-0.071217108,-0.075577836,-0.036234687,-0.158680063,-0.072717964,1.363276039,2.126731731,-5.264772165,-4.337665443,-3.203666489,-6.424996765,-6.659254288,-5.69827784,-4.471984568,-2.098540891 -3463,I206H,0.022876997,-0.073986494,-0.022999822,-0.051760515,-0.490274334,-0.00326561,0.023562109,0.022191885,0.042754319,-0.010723865,-0.137249122,-0.094826348,0.048826704,-0.026899762,-0.076621267,-0.464876178,-0.51567249,1.341771563,1.761573073,-5.219966,-5.158350525,-4.204643242,-5.053256409,-5.736261345,-5.947318481,-4.696089267,-3.256977194 -3464,I206K,-0.016521525,-0.052681132,-0.003651442,-0.018567651,-0.166908908,0.102245973,0.062402894,-0.095445944,0.076570818,0.037531549,-0.142893812,0.023802915,-0.031105798,0.03388351,-0.071018812,-0.142929425,-0.190888391,1.339444345,2.232258039,-2.355398444,-3.101410057,-2.386978638,-2.402503037,-1.429256905,-2.456843582,-2.284658349,-0.886288148 -3465,I206M,0.04019459,0.033615614,0.042878135,0.018242996,-0.031823082,0.030628628,0.109005315,-0.028616136,0.057253978,0.147934519,-0.080703292,0.036964361,0.048791908,0.115393419,-0.078907427,-0.012413142,-0.051233021,1.253934922,2.705641397,-0.491437813,-0.919427811,-1.055595886,-0.15063781,0.052233101,-0.383760658,-2.060464331,-1.233992727 -3466,I206L,0.041972252,-0.012020969,0.003075039,-0.027907064,-0.062484206,-0.012539835,0.039540011,0.044404492,0.018396399,0.045216431,-0.069258368,-0.030213991,0.036364068,-0.005862829,-0.049951298,-0.109780622,-0.01518779,1.280598282,2.180638079,-0.036553122,0.55564579,-0.105347061,0.059454048,0.037506355,-0.730024742,-1.988781049,0.800509113 -3467,I206N,-0.07639246,-0.097453212,-0.084877025,-0.115021107,-0.545276258,-0.032856908,-0.10187433,-0.05091059,0.019878297,-0.097045356,-0.097861067,-0.069200375,-0.100553674,-0.100784376,-0.129257838,-0.583464676,-0.50708784,1.560446251,1.82713522,-4.219549219,-4.542879295,-3.710311043,-2.970466324,-4.730273148,-5.143816284,-3.899577423,-2.183210967 -3468,I206Q,0.029201497,-0.078811444,-0.042334195,-0.025677079,-0.043686221,0.002203199,0.004296914,0.054106079,0.045781937,0.009039369,-0.166662257,-0.074263676,-0.010404714,-0.041794624,-0.009559534,-0.117864662,0.030492221,1.230533656,2.126666669,-1.522694937,-1.917375771,-1.916713539,-0.837482803,-0.663381546,-2.278521027,-2.170622594,-1.412007112 -3469,I206P,0.000471761,-0.291522652,-1.779102921,-2.247104658,-2.793581331,0.050500987,0.018342382,-0.017398861,0.022158294,-0.203388455,-0.379656848,-2.085341555,-1.472864286,-2.312040052,-2.182169264,-2.727773562,-2.859389099,0.641959004,-0.221006544,-7.401030563,-6.512406586,-6.871379822,-7.617098854,-7.449321152,-8.554946404,-7.193116032,-6.609444902 -3470,I206S,0.014117386,-0.060086527,-0.029719634,-0.032810553,-0.109283774,0.000259584,0.012277943,0.015956829,0.039923626,-0.013575131,-0.106597922,-0.063212492,0.003773224,-0.01245919,-0.053161915,-0.154436056,-0.064131492,1.516827237,2.312321322,-3.783834149,-3.734803543,-3.669640533,-3.487393883,-3.607306099,-4.420026688,-3.245276052,-2.93914146 -3471,I206R,0.025828252,-0.01377985,-0.016197196,-0.038110036,-0.096092213,0.011311628,0.026284887,0.025371617,0.0343773,0.05204758,-0.07960728,-0.068735768,0.036341376,-0.017784993,-0.058435079,-0.140715911,-0.051468515,1.317294567,2.17960245,-1.863715332,-1.234476639,-2.427891823,-1.72367675,-1.086188499,-2.846342949,-1.921414061,0.116348219 -3472,I206T,0.042614654,-0.022792241,0.000975041,-0.034564326,-0.092170431,-0.031852644,0.037801507,0.047427801,0.01514372,0.025286599,-0.07087108,-0.020312629,0.022262711,0.001674334,-0.070802985,-0.121416629,-0.062924232,1.319106307,2.243707257,-1.176565407,-1.446529579,-1.51588694,-1.515139503,-0.875823303,-0.529447708,-1.26535325,0.024509321 -3473,I206W,0.058103689,-0.053842374,-0.043425503,-0.050314221,-0.059908443,-0.002041336,0.072066766,0.044140612,0.024982288,-0.012563717,-0.09512103,-0.135897928,0.049046922,-0.042665477,-0.057962965,-0.137351878,0.017534992,1.394835485,2.216405331,-5.302861824,-3.824868736,-2.429698967,-5.167549477,-6.690173317,-8.402018623,-5.063644327,-1.201339427 -3474,I206V,0.069535824,0.016368188,0.02299752,-0.024435354,-0.052187525,-0.030983962,0.070100704,0.068970943,0.051695465,0.049900162,-0.017163787,-0.00046566,0.0464607,-0.012251211,-0.036619497,-0.099475313,-0.004899736,1.395511931,2.313337165,-1.346544633,-1.231473282,-1.425366547,-1.65223674,-0.760181358,-1.66346524,-2.454222638,-0.605950916 -3475,I206Y,0.040908949,0.040893773,-0.079761211,-0.008538211,-0.100407788,-0.109105181,0.046709356,0.035108541,0.093153478,0.134199098,-0.052411552,-0.140506514,-0.019015907,0.031847367,-0.048923789,-0.091428974,-0.109386602,1.327195343,2.296787114,-6.119303308,-6.407345352,-3.715326706,-7.455663673,-7.152918419,-5.86526239,-5.199908007,-1.28047204 -3476,D207A,-0.062229479,-0.045654257,-0.027258616,-0.031301506,-0.024022197,0.038410698,-0.05996719,-0.064491768,0.032718808,-0.020184848,-0.071123665,-0.042907107,-0.011610125,-0.018439979,-0.044163032,0.011925899,-0.059970292,1.178267571,2.593060595,-0.334295882,-0.001144165,-0.608751328,0.093880608,0.011962357,-1.16742688,-2.439769816,-0.795213639 -3477,D207C,0.010585694,-0.043857762,-0.003090153,0.005629061,-0.08019127,0.041584525,0.009075379,0.012096009,0.023033137,-0.066821471,-0.020894052,-0.018188746,0.01200844,0.014746,-0.003487878,-0.022340233,-0.138042306,1.184000001,2.533465974,-6.555776993,-6.234379272,-6.418387077,-7.165271652,-6.430414032,-6.53043293,-8.138107933,-8.923942929 -3478,D207E,-0.04176011,-0.051951306,-0.019379709,-0.033905602,0.004128037,0.027629155,-0.028227375,-0.055292844,0.021005601,-0.019637634,-0.084264977,-0.025794798,-0.012964619,-0.012942099,-0.054869104,0.040631973,-0.0323759,1.128027136,2.776403782,-0.662769107,-0.599143021,-0.88213916,-0.896062767,-0.400706825,-0.535793762,-1.601503474,-0.692290117 -3479,D207G,-0.038288475,-0.035304962,-0.016086804,-0.027988322,-0.016034947,0.046896712,-0.027638932,-0.048938017,0.00180474,-0.02555868,-0.045051244,-0.004173631,-0.027999977,-0.001736824,-0.054239819,0.023876772,-0.055946666,1.060478253,2.646715663,-1.376860916,-1.52169265,-1.366205795,-0.47899511,-1.038818863,-2.478592163,-2.905158732,-0.645666795 -3480,D207F,-0.040534289,-0.044215323,-0.048585087,-0.027121364,-0.184123466,0.056235372,-0.004906908,-0.07616167,-0.004511654,-0.041842409,-0.046588237,-0.0510629,-0.046107273,-0.019985381,-0.034257347,-0.148947954,-0.219298977,1.460766913,2.276557478,-6.505832027,-6.155939888,-5.583940941,-7.981839012,-6.631290581,-6.176149712,-6.781019749,-6.29822789 -3481,D207I,-0.046580737,-0.011509082,0.018161902,-0.024129632,-0.183733321,0.020730646,-0.028920302,-0.064241172,-0.006542496,0.043429902,-0.066448065,0.016490212,0.019833592,-0.004438268,-0.043820995,-0.086046632,-0.281420009,1.389820332,2.381473061,-4.437585504,-4.283929039,-4.380328903,-4.637267754,-3.772836502,-5.113565323,-5.193057651,-4.728460004 -3482,D207H,-0.041334043,-0.020158067,-0.025731559,-0.019124019,-0.02671686,0.05108352,-0.016771435,-0.06589665,0.020025284,-0.00252764,-0.037788493,-0.05388908,0.002425963,0.018489232,-0.056737269,-0.00844768,-0.044986039,1.225252326,2.372969189,-2.020236591,-1.64715464,-2.049554558,-2.397190468,-1.886979317,-2.12030397,-3.156065845,-2.693722337 -3483,D207K,-0.06931475,-0.071966898,-0.033428678,-0.041045916,-0.068487126,0.020119835,-0.048861057,-0.089768442,0.010045264,-0.062542673,-0.081391122,-0.005703034,-0.061154322,-0.004883892,-0.077207939,0.006778314,-0.143752565,1.160606965,2.538294051,-1.992011642,-1.977584084,-2.241929016,-2.974703156,-1.872360893,-0.893481064,-3.511829116,-1.301386837 -3484,D207M,-0.028001011,-0.021628026,-0.006265159,-0.00327726,-0.025048737,0.017259441,-0.008326609,-0.047675413,0.048785483,0.008112023,-0.051368075,-0.030716035,0.018185717,-0.025834175,0.019279656,0.038750784,-0.088848258,1.207092001,2.766146011,-4.588306856,-4.641037575,-4.223224129,-4.66292543,-4.428940506,-4.985406639,-5.386453963,-4.74635679 -3485,D207L,-0.040484176,-0.020028957,-0.004732899,-0.020144275,-0.064457659,0.037958257,-0.019282428,-0.061685924,-0.020499898,0.000762485,-0.040820398,-0.00531378,-0.004152017,-0.011351501,-0.028937049,-0.031204429,-0.097710889,1.269655504,2.461526146,-3.978099484,-4.030092598,-3.781398926,-4.376586693,-3.561358795,-4.14106041,-4.934837261,-4.268073053 -3486,D207N,0.005602492,-0.011764415,-0.008308064,-0.011479003,-0.010855562,0.073117438,0.027601269,-0.016396286,-0.047756732,-0.041906274,0.018377445,0.001324408,-0.017940536,0.031479565,-0.054437571,0.000168492,-0.021879615,1.130150153,2.550558713,-1.372388542,-1.050453354,-1.201484451,-2.44535659,-1.146509148,-1.018139168,-4.08296771,-1.675049237 -3487,D207Q,-0.064387329,-0.115558587,-0.051406943,-0.091283528,-0.072254373,0.026744773,-0.057842166,-0.070932492,0.016903379,-0.15554682,-0.075570353,-0.07914947,-0.023664416,-0.113222782,-0.069344274,-0.074834216,-0.069674529,1.463061064,2.441422517,-0.143463402,0.376668983,-0.052730705,-0.146319984,0.218932335,-1.113867638,-2.157923103,-1.295753837 -3488,D207P,-0.077697109,-0.033856525,-0.679715821,-1.926697154,-2.74751331,0.151843837,-0.044482223,-0.110911994,-0.034113888,-0.001209598,-0.066503452,-0.642376265,-0.717055376,-1.87347037,-1.979923938,-2.660629533,-2.834397087,2.019837199,0.915196731,-5.45259476,-5.561102211,-5.482878998,-5.603601982,-5.224078354,-5.391312256,-6.506493701,-5.374169984 -3489,D207S,-0.011899561,-0.032074722,0.002292015,-0.009120006,0.010865087,0.050958044,-0.001740461,-0.02205866,0.031620201,-0.024541536,-0.039607907,-0.004605499,0.009189529,0.008895522,-0.027135533,0.042116281,-0.020386108,1.040179426,2.597550479,-1.198819003,-0.63722921,-1.348418884,-1.581391525,-1.434955856,-0.992099541,-2.852653432,-1.361043428 -3490,D207R,-0.045857322,-0.035519088,-0.011863027,-0.017930281,-0.013780093,0.07738064,-0.041279604,-0.05043504,0.014072422,-0.007902792,-0.063135383,-0.015453965,-0.008272088,-0.003612958,-0.032247604,0.013756489,-0.041316675,1.124077095,2.466195628,-0.978487334,-0.576125092,-1.04181707,-1.114392593,-1.177271584,-0.98283033,-1.779659553,-0.893781565 -3491,D207T,-0.070470654,-0.054292584,-0.049724263,-0.030861444,-0.051384057,0.038294738,-0.066665173,-0.074276134,0.001027644,-0.051911654,-0.056673513,-0.05152922,-0.047919306,-0.02108244,-0.040640447,-0.016912026,-0.085856087,1.235117378,2.449877744,-1.01109523,-1.038826355,-1.191497635,-0.569880882,-0.413111763,-1.842159515,-2.078878442,-1.375848808 -3492,D207W,-0.06514415,-0.030409455,0.002782884,-0.007488766,-0.103181347,0.123116941,-0.047212799,-0.0830755,0.001140185,0.027637765,-0.088456675,0.006530867,-0.000965099,0.049810767,-0.064788299,-0.040590798,-0.165771896,1.374225786,2.568305003,-6.25035424,-5.852524048,-5.869268799,-6.78347905,-6.544884018,-6.201615288,-7.035980301,-6.049532508 -3493,D207V,-0.085287179,-0.054408889,-0.031817229,-0.042565252,-0.1555887,0.082194495,-0.04350517,-0.127069187,-0.005456108,-0.018672947,-0.09014483,-0.025355229,-0.038279229,-0.013008073,-0.072122431,-0.080397696,-0.230779703,1.354216729,2.413301012,-3.903306496,-3.836464531,-4.161396851,-3.790867516,-3.457358047,-4.270445534,-5.067221093,-3.843838272 -3494,D207Y,-0.043655291,-0.038464558,-0.050618475,-0.022883952,-0.089946259,0.04955973,-0.042207005,-0.045103576,-0.022475999,-0.004931327,-0.071997788,-0.035946775,-0.065290175,-0.005496291,-0.040271612,-0.063422925,-0.116469593,1.320972621,2.407009106,-5.04699563,-4.578328491,-4.868100067,-6.429979172,-5.04487532,-4.313695099,-5.522636609,-4.374461222 -3495,W208A,-0.06362903,0.13914769,0.025023449,-1.467070906,-1.916460922,0.002973479,-0.027025875,-0.100232185,0.001911014,0.046197388,0.232097992,0.043929489,0.006117408,-1.286832171,-1.647309641,-2.211637873,-1.62128397,0.554059477,0.709617885,-11.14622098,-9.735963074,-11.666325,-11.71518243,-10.94425308,-11.66938132,-6.481078749,-2.614055917 -3496,W208C,-0.05714613,0.121219803,-0.029726779,-1.553160117,-2.212615247,0.038373563,-0.011717733,-0.102574526,-0.04853718,-0.001929651,0.244369257,-0.030530863,-0.028922695,-1.439562343,-1.66675789,-2.389191629,-2.036038864,0.833337838,0.720586869,-12.90465062,-12.87979081,-13.23821391,-13.10976931,-12.76844306,-12.52703603,-8.299972988,-4.964786465 -3497,W208E,-0.062775886,0.091706054,0.006469814,-1.551703331,-2.293189931,-0.002036211,-0.030193206,-0.095358566,0.097109643,-0.027189336,0.210601443,0.009385209,0.003554419,-1.66232332,-1.441083342,-2.196979258,-2.389400604,0.8219954,0.693546304,-13.69049042,-12.98545329,-14.70380125,-13.72492908,-13.78242682,-13.25584165,-9.371033667,-6.297051989 -3498,W208D,-0.051759838,0.066382951,-0.003051528,-0.26760631,-1.792940808,-0.000971192,-0.012447514,-0.091072162,-0.083232493,-0.037924276,0.170690178,-0.025428053,0.019324998,-0.097157113,-0.438055506,-1.89574486,-1.690136755,0.877627705,1.30889981,-12.22653123,-11.05288818,-12.83011995,-12.06188233,-13.23565437,-11.95211134,-7.643585477,-4.229648852 -3499,W208G,-0.063815187,-0.060850883,-1.422979542,-2.096079147,-2.512143778,0.012052073,-0.028916697,-0.098713677,-0.055898818,-0.049935004,-0.071766762,-1.424073888,-1.421885195,-2.067188574,-2.124969719,-2.511667881,-2.512619675,0.807271849,0.059876586,-11.549307,-11.03348699,-12.08071264,-10.49850535,-11.93664297,-12.19718703,-7.471623646,-5.313393607 -3500,W208F,-0.011549844,0.102015059,0.038283691,0.036925221,-0.969442853,-0.020340716,0.028571791,-0.051671479,0.114422618,0.021433434,0.182596683,-0.00268094,0.079248321,-0.030163926,0.104014367,-1.03912241,-0.899763295,0.817433272,1.368028299,-10.20756454,-9.828221664,-8.720377441,-10.94900566,-8.882167419,-12.65805051,-7.600700524,-2.814565613 -3501,W208I,-0.082512398,0.119666521,-0.082327535,-1.653077336,-2.544678199,-0.009955122,-0.035991284,-0.129033512,-0.069221779,0.037135375,0.202197666,-0.081402577,-0.083252493,-1.454521501,-1.85163317,-2.330364573,-2.758991824,0.804919196,0.715346478,-10.30938004,-11.89781244,-10.16971111,-12.90300116,-9.402437592,-7.173937912,-7.438310078,-0.550210024 -3502,W208H,-0.036072135,0.125026552,0.018422025,-1.591976934,-2.123041474,0.03256793,0.014804086,-0.086948355,0.146797427,-0.011507168,0.261560271,0.015476496,0.021367554,-1.443087479,-1.740866388,-2.292601613,-1.953481335,0.804984148,0.717418144,-11.1604726,-10.58365697,-13.30779218,-10.09392615,-10.84641489,-10.97057284,-7.683621163,-3.684233724 -3503,W208K,-0.07054185,-0.592445081,-1.783025306,-2.134174362,-2.266433854,0.072954884,-0.038273935,-0.102809765,-0.050996959,-0.635629069,-0.549261092,-1.757851344,-1.808199267,-2.020754787,-2.247593936,-2.794292814,-1.738574894,3.056372756,1.188732294,-13.72657658,-13.06398225,-15.94034407,-13.60854117,-13.5441643,-12.47585112,-9.82486594,-6.5601611 -3504,W208M,-0.015287271,0.149248282,0.016696593,0.067860262,-0.953390179,0.030505741,0.026027924,-0.056602465,-0.090411078,0.027860672,0.270635891,0.003099545,0.03029364,0.012474954,0.12324557,-0.831937235,-1.074843123,0.806698289,1.396652558,-9.763819188,-10.08924507,-9.51038797,-11.33913677,-8.955105057,-8.925221069,-6.235516854,-2.450617323 -3505,W208L,-0.052013305,0.149693474,0.037001321,0.071910959,-1.401179782,0.039930588,-0.012083788,-0.091942821,-0.038101978,0.040904146,0.258482801,0.044734686,0.029267955,0.059302137,0.08451978,-1.627490148,-1.174869416,0.59231512,1.310115683,-8.678854318,-9.243062851,-8.246988525,-10.67182776,-6.881146164,-8.351246292,-5.768200319,-1.128836958 -3506,W208N,-0.049050576,0.186140764,-0.041764751,-1.613412832,-2.496360039,0.044879293,-0.036276155,-0.061824996,-0.023464288,0.076627632,0.295653895,-0.011726737,-0.071802764,-1.492869815,-1.733955848,-2.524685857,-2.468034221,0.74995331,0.70905245,-12.42419212,-12.44121762,-13.13643768,-11.95745391,-12.86048991,-11.72536151,-8.149273276,-3.58038137 -3507,W208Q,-0.07514014,0.110468458,-0.221968208,-1.689327135,-2.720273122,0.030998695,-0.039981666,-0.110298614,-0.030876787,-0.020839491,0.241776407,-0.108063336,-0.33587308,-1.656697149,-1.721957121,-2.641088541,-2.799457702,0.929496817,0.70740533,-11.71181391,-12.04912492,-13.20082405,-11.92709264,-11.42127155,-9.960756355,-8.352695506,-5.331634443 -3508,W208P,-0.070865373,-1.016465859,-1.906857375,-2.178265016,-3.079917716,0.03426964,-0.040284479,-0.101446266,0.005411839,-1.084570088,-0.948361629,-1.80789324,-2.005821509,-2.154899166,-2.201630866,-2.889413085,-3.270422347,3.171455039,1.075573397,-14.66319947,-13.65804826,-15.47036027,-15.33712205,-13.97173758,-14.87872918,-8.816572793,-5.081971658 -3509,W208S,-0.031524286,0.137367,-0.190245273,-1.689451822,-2.154436131,0.018330803,0.011818549,-0.07486712,-0.170348276,0.003980365,0.270753634,-0.134922921,-0.245567624,-1.618133108,-1.760770536,-2.307026994,-2.001845268,1.053129377,0.722979365,-11.89392921,-11.40514136,-11.87418256,-11.64802093,-12.12481061,-12.41749059,-7.672475359,-4.253343731 -3510,W208R,-0.051789285,-0.286493544,-1.525321092,-2.106920362,-2.827959969,0.047430124,-0.020079081,-0.083499488,0.000852041,-0.254543917,-0.31844317,-1.525756727,-1.524885456,-2.071778577,-2.142062146,-2.636831816,-3.019088122,2.681788097,1.03146795,-10.84669366,-11.72806085,-12.06998188,-10.35545567,-11.65653661,-8.423433273,-8.078607466,-5.329241247 -3511,W208T,-0.069405571,0.12638569,-0.187928334,-1.676308318,-2.420402242,0.038934267,-0.025191514,-0.113619627,-0.046444564,0.02742236,0.225349019,-0.114664033,-0.261192634,-1.727916859,-1.624699777,-2.578936347,-2.261868137,0.940672943,0.700051781,-9.868649854,-10.50319552,-10.52746169,-10.08416125,-7.886942795,-10.34148801,-6.895188955,-2.051046061 -3512,W208V,-0.0568276,0.135182222,-0.802637307,-1.800203315,-2.66192783,0.031385009,-0.021477205,-0.092177994,-0.176431749,0.046044297,0.224320146,-0.516499059,-1.088775554,-1.632114802,-1.968291827,-2.824782136,-2.499073524,1.830374677,0.905720545,-11.08542168,-12.06979723,-11.31650025,-12.11756081,-10.29271818,-9.630531952,-5.40677861,-1.793880427 -3513,W208Y,-0.075573493,0.128724001,0.028299705,0.045436385,-1.429065287,-0.021150189,-0.047613332,-0.103533654,-0.127213726,-0.000419124,0.257867125,0.010178378,0.046421032,0.021793292,0.069079478,-1.632434084,-1.22569649,0.547558699,1.307636809,-10.00539543,-10.22075278,-9.609655212,-9.615537514,-9.49898674,-11.08204491,-7.831612207,-3.398521745 -3514,M209A,0.011769685,0.184115779,0.017205486,-1.619943327,-2.03056525,0.035001732,0.020360289,0.003179081,-0.034959897,0.012606257,0.3556253,-0.03689849,0.071309461,-1.264843886,-1.975042767,-2.370179306,-1.690951193,0.947747434,0.750002065,-8.234347058,-7.832445961,-8.035463829,-7.929872177,-8.600264084,-8.77368924,-8.416307439,-6.307476726 -3515,M209C,0.05786613,0.229378553,0.02504521,0.098222533,-1.152460299,-0.072790773,0.071621385,0.044110874,-0.006721416,0.039998431,0.418758674,0.032430105,0.017660315,-0.000171948,0.196617013,-1.634852156,-0.670068441,0.61234398,1.310415243,-10.98406441,-10.75067282,-10.42047305,-10.41566914,-11.08248943,-12.25101762,-10.48843537,-10.30909939 -3516,M209E,-0.032227282,-0.881310196,-2.304691151,-2.319253869,-2.921396059,0.014029284,-0.021535283,-0.042919281,0.030023598,-0.907426804,-0.855193588,-2.708925136,-1.900457166,-2.195325016,-2.443182722,-2.543698485,-3.299093632,0.339253448,-0.620805285,-11.28385336,-10.61390013,-10.94904324,-10.61903944,-11.64503513,-12.59224886,-10.48843537,-10.30909939 -3517,M209D,-0.017045494,-1.564393614,-2.095602608,-2.701630668,-3.002742861,0.012050572,-0.02065937,-0.013431618,-0.089672907,-1.855709602,-1.273077625,-2.172908096,-2.01829712,-2.261367966,-3.141893369,-2.910771431,-3.094714291,-0.597917121,-1.123790675,-11.68870713,-10.9599225,-11.60323131,-10.86522088,-12.01450696,-13.00065399,-10.48150989,-10.27089108 -3518,M209G,-0.016201071,0.155156447,-0.140045664,-1.732685089,-2.678930153,0.006776038,0.008220426,-0.040622568,-0.017959241,0.01724087,0.293072023,-0.142909779,-0.137181549,-1.679511361,-1.785858816,-2.596776458,-2.761083847,1.018145967,0.712201933,-10.03010107,-8.954619911,-9.728741966,-9.517863945,-9.818865494,-12.13041405,-8.930507795,-6.952508032 -3519,M209F,-0.029783629,0.134616246,-0.143528793,-1.615656226,-2.914586017,-0.015163509,-0.023790583,-0.035776674,0.006690135,0.006832328,0.262400163,-0.151718797,-0.135338789,-1.461237072,-1.77007538,-2.851003226,-2.978168807,1.109838957,0.752625051,-7.451167949,-8.403774284,-5.547861191,-6.762965027,-7.845784042,-8.6954552,-7.347199345,-4.154184197 -3520,M209I,-0.053541278,0.127687975,-0.949520824,-1.857301499,-2.834504952,-0.068630775,-0.026762343,-0.080320212,-0.004646334,0.063909442,0.191466507,-0.711026808,-1.188014839,-1.723765964,-1.990837034,-2.771109438,-2.897900466,2.041826766,0.960267261,-6.198722543,-5.259169098,-5.741379936,-6.397368599,-7.178577965,-6.417117119,-7.320596617,-4.760548719 -3521,M209H,-0.01826486,-1.286444407,-2.307058752,-2.185120833,-2.875308652,0.059194006,0.0230848,-0.05961452,0.007555643,-1.317929282,-1.254959531,-2.237187767,-2.376929736,-2.325647637,-2.044594029,-3.151142361,-2.599474942,0.053345004,-0.807668193,-11.27219172,-11.05976984,-10.13057114,-10.97843627,-11.24425077,-12.94793058,-9.75981237,-7.503679155 -3522,M209K,-0.059917095,-1.066810284,-2.055304181,-2.24937787,-2.939565689,0.02731059,-0.03285155,-0.08698264,-0.029315557,-0.97892152,-1.154699048,-1.949332527,-2.161275834,-1.912853661,-2.585902079,-2.863287121,-3.015844256,3.491773005,1.412317995,-10.59383957,-10.00724699,-10.39223649,-9.654688599,-10.73265281,-12.18237295,-9.858186806,-7.503679155 -3523,M209L,0.183699056,0.14036505,0.059101976,0.069382862,-0.620492384,-0.049808531,0.06463159,0.302766522,-0.032767502,0.051759862,0.228970237,0.008626496,0.109577455,-0.039284526,0.17805025,-0.73311796,-0.507866807,0.844428716,1.424685583,-3.254801871,-5.433984184,-2.252779243,-2.393698692,-3.59259185,-2.600955383,-4.795122265,0.00491984 -3524,M209N,0.039360648,-1.031817908,-2.374158591,-2.392141022,-2.781298845,0.06342757,0.058570541,0.020150754,0.04768915,-1.064170155,-0.999465661,-1.983428639,-2.764888543,-2.372918506,-2.411363537,-2.721291975,-2.841305714,0.265210349,-0.665009145,-10.38831378,-9.438246902,-10.20355776,-9.379296417,-11.1266406,-11.79382724,-9.301837558,-7.062170028 -3525,M209Q,0.353013124,-0.655310636,-0.473593183,-2.121439728,-2.48502129,-0.001493654,0.050969865,0.655056382,-0.030937244,0.01274323,-1.323364501,-0.323037541,-0.624148824,-2.07188851,-2.170990946,-2.545200716,-2.424841864,1.312499577,0.670536587,-11.31080268,-10.76001436,-10.99082561,-10.67722396,-11.43665037,-12.68929912,-10.48843537,-10.30909939 -3526,M209P,0.000614608,-1.427255247,-2.018035649,-2.450415844,-2.830617872,0.0278144,0.032162208,-0.030932992,-0.096449837,-1.685222221,-1.169288272,-2.073776623,-1.962294675,-2.308364529,-2.592467158,-2.878586748,-2.782648996,-0.060761133,-1.067142865,-11.35745531,-10.74641993,-11.15130801,-10.73334699,-11.68765267,-12.46854893,-10.48843537,-10.30909939 -3527,M209S,-0.015921345,0.12963538,-1.417578998,-2.274155201,-2.819777634,0.034742444,0.024844751,-0.056687441,-0.018675398,-0.015144949,0.274415709,-1.347648516,-1.48750948,-2.496806226,-2.051504176,-2.970118432,-2.669436836,0.65588571,0.059889592,-10.85075517,-9.864848755,-10.51553117,-10.3650342,-11.12579,-12.38257173,-10.48843537,-10.30909939 -3528,M209R,-0.058272715,-1.390937499,-2.04965505,-2.350668649,-3.260522815,0.02393047,-0.035502469,-0.081042961,-0.118403263,-1.671142238,-1.11073276,-1.963517148,-2.135792952,-2.529098273,-2.172239025,-3.354592997,-3.166452633,-0.229121918,-1.083860858,-11.85905716,-11.16214573,-11.54105358,-11.09559925,-11.95864187,-13.53784536,-10.46529589,-10.13596353 -3529,M209T,-0.007710137,0.176805583,-0.718018598,-2.244010031,-3.405201876,-0.025451563,-0.005623505,-0.009796768,0.009907965,0.000457575,0.353153591,-0.46229411,-0.973743086,-2.283147741,-2.20487232,-3.330491214,-3.479912537,1.351422269,0.575689633,-7.227355138,-6.77149353,-6.863253716,-7.110683807,-7.655381821,-7.735962814,-7.88333753,-5.281195189 -3530,M209W,0.006535758,0.154341123,-0.292802237,-1.863962693,-2.349063279,-0.061086979,0.007188893,0.005882622,-0.01087495,0.05593606,0.252746186,-0.254722626,-0.330881847,-1.732939056,-1.99498633,-2.479252534,-2.218874024,1.258280884,0.732993908,-11.51891489,-11.68998074,-10.77149966,-10.29609209,-11.69972744,-13.13727451,-10.48843537,-10.30909939 -3531,M209V,0.024066897,-0.026424353,-1.53298494,-2.294382739,-2.529281553,-0.037321787,0.045162247,0.002971547,-0.018298257,-0.092757287,0.039908582,-1.65002935,-1.41594053,-2.361738511,-2.227026966,-2.630930734,-2.427632372,0.792112394,0.01177928,-7.980053839,-7.457436241,-7.307254128,-7.754030678,-8.78968718,-8.59186097,-8.500501821,-6.359663502 -3532,M209Y,-0.11401198,-0.951825911,-1.978243097,-2.53581615,-2.924973973,0.027968773,-0.112954076,-0.115069884,0.062714725,-1.120606756,-0.783045066,-1.765164184,-2.19132201,-2.455684045,-2.615948254,-2.804057515,-3.045890431,2.43024275,0.403165003,-10.41650902,-10.31264651,-8.941965523,-9.479626305,-10.47513232,-12.87317445,-9.349987951,-6.747933534 -3533,E210A,0.405231086,0.388018931,-0.050120514,-0.054879976,-0.372386731,-0.079054029,0.016454322,0.79400785,0.056278538,0.062930556,0.713107306,0.01695591,-0.117196938,0.065281245,-0.175041196,-0.145860111,-0.598913351,1.239393249,2.108541614,-2.669873622,-1.880144669,-2.841089638,-2.159469109,-3.988266563,-2.480398132,-3.302840476,0.07835725 -3534,E210C,0.043418981,-0.090853022,0.011745722,0.027111991,0.150784067,-0.042845637,0.100126761,-0.0132888,-0.042618706,0.001259993,-0.182966037,-0.03288403,0.056375473,-0.032383407,0.086607389,-0.107380704,0.408948838,1.102568107,2.054550149,-6.143429878,-5.881696503,-5.688019089,-5.653897339,-7.094295319,-6.399241142,-5.429605626,-2.362635222 -3535,E210D,-0.010470772,-0.006385618,0.052059101,0.056391822,-0.158082654,-0.058545061,0.029365681,-0.050307224,0.070972484,0.096494939,-0.109266175,0.037748905,0.066369296,0.073681228,0.039102415,-0.339537219,0.023371912,0.839687452,1.57317866,-4.150981783,-3.708028183,-2.963318542,-3.554049492,-5.190730911,-5.338781784,-5.609011628,-2.131235656 -3536,E210G,0.117846663,0.126148046,-0.008503527,0.021204341,-0.326654622,-0.068688007,0.020512616,0.215180709,0.022742514,0.05511795,0.197178141,0.00850118,-0.025508233,0.023253772,0.019154909,-0.523720711,-0.129588533,0.60147228,1.411338368,-5.603778752,-2.739109024,-5.123212776,-6.124613571,-6.702940895,-7.329017494,-5.367433951,-0.088635871 -3537,E210F,-0.049800446,-0.029488684,0.027137356,0.001953757,0.145238067,-0.006087363,-0.005208486,-0.094392406,0.037558342,0.056947309,-0.115924676,0.064445561,-0.01017085,0.015225845,-0.011318331,-0.098144602,0.388620736,1.422248138,2.445432577,-5.900053694,-5.520920746,-4.974382675,-6.004401756,-7.318266014,-5.682297279,-5.045289746,-2.286146791 -3538,E210I,-0.023842879,-0.072426141,0.038094362,0.069639526,0.348570843,-0.021439063,0.020258062,-0.06794382,-0.009407697,0.112917263,-0.257769545,0.070001847,0.006186877,0.091725097,0.047553954,0.079605569,0.617536116,1.078747964,3.00070599,-0.512143542,-0.409992271,-0.834536385,-0.620519615,-0.852122719,0.156453278,-2.233015221,-0.135170692 -3539,E210H,0.004405637,-0.012123861,-0.015931688,0.03566448,0.153639001,-0.068999807,0.038263674,-0.0294524,0.005639856,0.089031883,-0.113279604,-0.024095777,-0.007767598,0.046433383,0.024895577,-0.143831665,0.451109667,1.310114585,2.176296874,-5.176834471,-4.262331085,-4.638233284,-6.269197067,-5.714887589,-4.999523331,-5.778200838,-2.151249966 -3540,E210K,-0.009865764,-0.070920553,0.011305285,0.03523272,0.232897995,-0.060023106,0.041690078,-0.061421606,0.005435774,0.035212819,-0.177053924,0.002658881,0.019951689,0.017541138,0.052924301,-0.133046054,0.598842043,1.183955717,2.102080861,-1.779657755,-1.452371071,-1.83388015,-2.506539726,-2.045710793,-1.059787033,-3.811103037,0.758752321 -3541,E210M,-0.028603721,-0.057613261,0.021951169,0.031421455,0.194174986,-0.044399882,0.011077188,-0.06828463,0.009015722,0.055138781,-0.170365303,0.040091269,0.003811069,0.039579061,0.023263849,-0.053265277,0.441615248,1.171423235,2.36905779,-3.261894604,-3.104293907,-3.50914991,-3.506219002,-4.114300858,-2.075509346,-4.081908536,-1.774940411 -3542,E210L,0.002445311,-0.00900026,0.005243687,0.011845808,-0.156003987,-0.027440425,-0.010908936,0.015799557,0.022582748,0.06093588,-0.0789364,0.006664232,0.003823142,0.021113596,0.002578019,-0.226607992,-0.085399981,1.402695897,2.093299002,-2.346255745,-2.551316429,-2.470706978,-2.227656799,-3.613330505,-0.868268013,-2.940988705,0.416533108 -3543,E210N,0.022183999,0.002682766,0.000198222,0.055981698,0.082515748,-0.055851987,0.086691668,-0.042323671,0.00129131,0.082542581,-0.07717705,0.01791876,-0.017522317,0.020693168,0.091270227,-0.245414188,0.410445683,1.057480628,1.791401693,-5.130836455,-4.147608322,-5.178827713,-5.017601799,-5.815974838,-5.494169601,-5.103757109,-1.986481164 -3544,E210Q,0.029467628,0.042838032,-0.010458627,0.079244332,0.054612238,-0.00604481,0.029088589,0.029846667,0.015534909,0.104379383,-0.018703319,0.029768204,-0.050685457,0.086615817,0.071872846,-0.000321649,0.109546125,1.049841855,2.635588792,-1.165588857,-1.144936691,-1.093659943,-1.539025154,-1.110156448,-0.940166046,-2.556013994,-0.7210337 -3545,E210P,0.250233874,-0.7178393,-1.888998106,-1.86261881,-1.742334732,0.021406087,-0.045602151,0.546069898,0.098033396,-1.070539519,-0.36513908,-2.471627817,-1.306368394,-2.173774421,-1.551463198,-2.618761029,-0.865908434,0.37096098,-0.668988192,-8.630677802,-7.71627108,-8.256324524,-8.49186174,-10.31446027,-8.37447139,-7.979180603,-5.505594114 -3546,E210S,0.025652073,-0.027052058,-0.003643922,0.027287048,-0.423217187,-0.092347812,0.058452923,-0.007148778,0.012297854,0.038846802,-0.092950917,-0.003645981,-0.003641863,0.038008967,0.016565128,-0.57125288,-0.275181494,0.554150851,1.390570077,-4.35257854,-3.62846814,-3.292987877,-3.575374359,-6.025782181,-5.240280144,-3.745985584,0.106292344 -3547,E210R,0.068183602,0.013112317,-0.00369791,0.016560909,0.07051385,-0.041405924,0.044509415,0.091857788,0.057476125,0.042053536,-0.015828903,0.003214266,-0.010610085,0.02296335,0.010158468,-0.144723792,0.285751492,1.413424846,2.246096252,-2.565136256,-2.204315186,-2.234721687,-2.877466049,-3.500263908,-2.008914452,-3.150688365,0.674518058 -3548,E210T,0.042386079,-0.00265192,-0.046493902,0.016081757,-0.342551855,-0.062252056,0.050355392,0.034416765,0.028799909,0.054291674,-0.059595514,-0.026601157,-0.066386647,-0.005856914,0.038020427,-0.290734877,-0.394368833,0.833966965,1.606469575,-2.868481227,-2.137548599,-2.085857933,-2.598519135,-4.066275429,-3.45420504,-3.704598044,-0.106336189 -3549,E210W,0.012151111,-0.050290363,0.001876334,0.008089816,0.10454532,0.007023058,0.033860823,-0.009558601,0.02065182,0.016412327,-0.116993052,-0.002385247,0.006137914,-0.014711869,0.0308915,-0.119579835,0.328670474,1.183900381,2.056735716,-8.402763823,-7.40000161,-8.425591705,-8.747386467,-10.12834035,-7.312498978,-6.965637573,-4.397539683 -3550,E210V,0.094897041,0.096517642,-0.011035055,0.027370832,-0.1782236,-0.051246006,-0.000451825,0.190245907,0.034669544,0.056379266,0.136656018,0.000634062,-0.022704172,0.023163938,0.031577726,0.005762714,-0.362209914,1.150298002,2.569292771,-0.290004659,-0.232349403,-1.070384277,0.098878334,-0.69243856,0.446270615,-2.018290134,0.11553045 -3551,E210Y,-0.000453559,-0.065894385,0.044509316,0.031305032,0.355790663,0.026906001,0.08020906,-0.081116178,0.111352968,0.063311636,-0.195100405,0.058407606,0.030611025,-0.009979298,0.072589362,0.005709788,0.705871537,1.206364278,2.599664057,-6.292568446,-4.966194641,-5.797284477,-6.646789093,-8.34468145,-5.707892571,-5.604529161,-2.452820746 -3552,A211C,0.165597556,-0.330561522,0.065873025,-0.020063676,-0.286941361,-0.090317373,-0.051380898,0.382576009,-0.034893658,0.009849609,-0.670972653,0.064905899,0.06684015,-0.015475902,-0.02465145,0.018601742,-0.592484464,1.27048636,2.589348045,-7.11529586,-7.338139877,-8.034015656,-6.991797073,-7.235534256,-5.976992439,-6.388615029,-4.753808458 -3553,A211E,0.040779795,-0.000012,0.073465257,0.076926871,-0.003246366,0.021890841,-0.021297886,0.102857475,-0.001887013,0.07817866,-0.078202738,0.139443723,0.00748679,0.033456118,0.120397623,0.098256785,-0.104749516,1.04450295,2.768537148,-1.919563223,-1.505683266,-2.565458199,-2.347578384,-1.288588577,-1.89050769,-2.335297227,-0.727801826 -3554,A211D,-0.052752261,0.075491213,0.118134646,0.085846757,0.149351808,0.039283617,-0.042487185,-0.063017337,-0.003985289,0.077046036,0.07393639,0.145437985,0.090831306,0.132574413,0.039119101,0.054618954,0.244084662,0.963688861,2.732984773,-1.243541087,-0.643802406,-1.756328636,-1.28115126,-1.342334023,-1.194089111,-2.315357272,-0.683619103 -3555,A211G,-0.012761912,0.076806146,0.054519424,0.052699065,0.047543237,0.001702951,-0.037532417,0.012008594,-0.046374032,0.072329323,0.081282968,0.070716058,0.03832279,0.042426329,0.0629718,0.04937324,0.045713233,1.055561019,2.602399479,-2.150582678,-1.970054405,-2.517184853,-1.162150978,-3.37373645,-1.729786705,-2.304643025,-0.134907993 -3556,A211F,-0.088204586,0.016797164,0.019205139,0.013035036,-0.547828864,-0.073076836,-0.182317477,0.005908305,-0.049134097,0.006574018,0.02702031,0.109998666,-0.071588389,0.118595913,-0.092525842,-0.303039659,-0.792618068,0.777656075,1.582281234,-8.376490187,-10.01766257,-8.919344849,-7.219008667,-7.61880751,-8.107627342,-6.234884763,-4.033410673 -3557,A211I,-0.001845151,0.197216032,0.052569601,0.033817436,-0.664675484,0.013229461,-0.030018545,0.026328243,-0.006395173,0.004890238,0.389541825,0.044487994,0.060651208,0.021221662,0.04641321,-0.774315678,-0.55503529,0.591209788,1.364152618,-5.818475171,-5.902504601,-6.63425042,-4.723353653,-6.408024368,-5.424242813,-5.427792034,-4.356470351 -3558,A211H,0.002109154,0.127979186,0.060033759,0.07203824,0.106391861,0.026572092,-0.07414577,0.078364077,-0.05351316,0.10232096,0.153637411,0.102401485,0.017666033,0.074423284,0.069653195,0.053387639,0.159396083,0.954870595,2.808905419,-4.43532399,-3.961273567,-4.803433846,-4.162707008,-5.694847221,-3.554358307,-2.920817997,-1.568895044 -3559,A211K,-0.016473945,0.04691903,0.004852124,0.1012606,0.00473626,-0.169062084,-0.113662776,0.080714886,-0.092599791,0.307198699,-0.213360639,0.136327605,-0.126623357,0.161315268,0.041205932,0.088229028,-0.078756508,1.106945548,2.948048726,-4.749191087,-5.872164696,-4.997145584,-5.83884774,-5.190861092,-1.846936325,-5.2269561,-1.26059231 -3560,A211M,0.141218393,0.119000724,0.187974355,0.211863595,0.299713579,0.00877512,0.09013838,0.192298405,0.116779332,0.185870417,0.052131031,0.226739562,0.149209147,0.144181833,0.279545356,0.111662,0.487765158,0.86488049,2.984459774,-4.074415623,-4.497206955,-4.343359215,-3.843191231,-4.080276993,-3.608043724,-3.790586577,-3.4065451 -3561,A211L,-0.00962619,0.076960126,0.056369751,0.009543409,0.08435156,0.008232107,-0.057288506,0.038036127,-0.059179544,0.020111988,0.133808263,0.075556707,0.037182794,-0.010385142,0.029471959,0.001848087,0.166855032,1.082920395,2.637767187,-5.402906206,-6.025229111,-5.543777405,-4.858358162,-6.31787484,-4.269291512,-5.492110319,-1.865964711 -3562,A211N,-0.081826003,-0.049166152,0.045194104,-0.025987878,0.007469645,-0.059988838,-0.120313377,-0.043338629,0.129151681,-0.067647803,-0.0306845,0.070755072,0.019633136,-0.104386766,0.05241101,-0.076015365,0.090954654,1.344865886,2.240470862,-2.144776646,-2.626895439,-2.747247345,-1.857444908,-2.315781029,-1.176514511,-2.370767461,-0.801299206 -3563,A211Q,-0.131027262,0.083144954,-0.037549245,-0.001991983,0.085666892,0.011033529,-0.190135063,-0.07191946,-0.027119261,0.072593818,0.093696089,0.043757473,-0.118855962,0.048014839,-0.051998804,0.065541993,0.10579179,1.248596664,2.964181393,-3.578374222,-3.71016494,-4.322492805,-3.727269501,-3.931403519,-2.200540344,-3.971425196,-1.17057196 -3564,A211P,0.077379866,-0.172215319,0.043309608,-1.143943523,-1.621459471,-0.074692645,-0.027627478,0.18238721,-0.043907176,0.038788508,-0.383219146,0.040794409,0.045824807,-0.995269783,-1.292617263,-1.69100268,-1.551916261,2.797967356,2.121657129,-6.497865518,-5.809353973,-6.544515381,-6.1851129,-8.009903549,-5.940441788,-5.664476175,-5.075258983 -3565,A211S,0.080007247,-0.098643823,0.054251319,0.017855886,-0.057107732,0.009393837,-0.004738223,0.164752717,-0.03949482,0.001128053,-0.198415699,0.010390116,0.098112522,-0.044411074,0.080122846,-0.019927625,-0.094287838,1.27419062,2.509069687,-2.999351971,-3.468783981,-3.115811638,-2.505376686,-4.054406525,-1.852381027,-3.646082357,-1.787018782 -3566,A211R,0.021456189,0.00490232,0.050610907,0.066860696,0.028937467,0.031171065,-0.051059065,0.093971443,-0.023898274,0.072513825,-0.062709186,0.08638229,0.014839523,0.059096865,0.074624527,0.07122327,-0.013348336,1.168924577,2.954224601,-4.138032835,-4.393217674,-5.532374199,-3.853051537,-5.59099025,-1.320530518,-2.877160546,0.026331551 -3567,A211T,-0.02376757,0.094665922,0.03166356,0.026301236,-0.316316504,-0.032809175,-0.052790684,0.005255544,-0.033685606,0.108324398,0.081007446,0.04661335,0.01671377,-0.003091797,0.055694268,-0.270891007,-0.361742001,1.04127448,1.748284181,-3.439151752,-3.894630836,-3.415350777,-2.771771118,-4.492446243,-2.621559784,-3.675758358,-1.821075286 -3568,A211W,0.050143737,-0.162096842,0.053618861,-0.013974251,-0.810289894,0.038888442,-0.118045516,0.218332989,-0.015609414,0.069370451,-0.393564134,0.070529796,0.036707925,0.022107978,-0.050056479,-0.384344599,-1.236235188,0.913367298,1.577427361,-8.729997198,-9.066754257,-10.50896852,-8.368019936,-8.706284088,-6.99995919,-6.259128764,-4.675589372 -3569,A211V,-0.000675747,0.105957516,0.046432544,0.080167616,-0.649735281,-0.010412309,-0.032570517,0.031219023,-0.071782057,0.117682649,0.094232383,0.123897276,-0.031032188,0.085038508,0.075296724,-0.699217822,-0.600252739,0.350906775,1.341018564,-5.881790659,-5.886832954,-6.439836929,-5.573355583,-5.858073151,-5.650854675,-5.953061484,-4.607695052 -3570,A211Y,0.054087476,-0.010895512,0.157771256,0.077594306,-0.353034012,-0.045219398,-0.074972939,0.18314789,-0.047128115,0.177455406,-0.19924643,0.16887243,0.146670081,0.032358028,0.122830584,-0.031396804,-0.67467122,1.321109761,2.547728722,-8.209191608,-9.055009644,-8.795346016,-7.325202705,-7.666591438,-8.203808235,-6.169640514,-3.904392184 -3571,D212A,0.067048026,-0.007268238,0.085416434,-0.048719386,-1.450938143,-0.060816566,0.073489956,0.060606096,0.034881477,0.041216548,-0.055753023,0.001802707,0.16903016,-0.137268515,0.039829744,-1.642854762,-1.259021523,0.798288437,1.320195467,-9.137807828,-8.047322449,-7.521845856,-11.19227575,-8.969851509,-9.957743576,-5.657073737,-0.268618658 -3572,D212C,0.042196129,0.118190169,0.067673032,-0.695130194,-2.102952115,-0.147179841,0.020206272,0.064185986,-0.023335482,0.078705861,0.157674476,0.061585163,0.073760901,-0.484522108,-0.905738279,-2.338430451,-1.867473779,1.506708722,1.282049832,-9.883662788,-9.760578873,-9.705652748,-11.28704755,-9.791674644,-8.873360123,-4.954221243,1.147943095 -3573,D212E,0.02848791,0.106854125,0.065040882,-1.12509824,-1.56686785,-0.147937816,0.059278553,-0.002302733,-0.017086532,-0.003351216,0.217059466,-0.022958282,0.153040046,-1.177929252,-1.072267227,-1.806528314,-1.327207385,2.267425571,1.596148081,-8.270353557,-8.041598907,-8.206011154,-6.930916565,-8.796123611,-9.377117546,-7.448054368,-2.675542949 -3574,D212G,-0.029872316,0.050154026,0.097812251,0.172463174,-1.068630148,-0.065869918,0.040584287,-0.100328919,0.040260254,0.059426037,0.040882014,0.003400339,0.192224163,0.03895267,0.305973677,-1.137002783,-1.000257512,0.628253195,1.336712476,-6.312953584,-5.602363861,-6.317978424,-6.742556625,-6.794542015,-6.107326996,-4.812017345,-0.286854059 -3575,D212F,-0.04949869,-0.280926648,-0.104026414,-1.580677415,-1.875844696,0.148430416,-0.147842267,0.048844888,-0.020506192,-0.043323744,-0.518529551,-0.168936328,-0.0391165,-1.895682486,-1.265672344,-2.193288329,-1.558401063,1.065252403,0.687370276,-16.61079407,-17.04480203,-17.14919669,-15.07832938,-17.44860095,-16.3330413,-9.887251498,-6.66660981 -3576,D212I,0.031287058,-0.232358867,-0.17885083,-1.42118526,-1.565837543,0.181870584,0.028829212,0.033744903,0.078373414,0.020063235,-0.484780968,-0.343093087,-0.014608573,-1.485508021,-1.356862498,-1.783113864,-1.348561221,3.57419437,2.593422806,-13.77856117,-12.79292319,-12.60661906,-15.0447496,-15.1203819,-13.32813211,-6.87835414,-0.660732642 -3577,D212H,0.062273658,0.026584936,0.043736705,-1.340260784,-1.683158038,-0.118795016,0.048369047,0.076178268,0.038575953,0.006374427,0.046795445,-0.007005447,0.094478856,-1.264813799,-1.415707769,-2.02105749,-1.345258585,2.511301559,1.689245108,-11.02462231,-11.4639108,-12.11021054,-9.97693502,-10.46261859,-11.1094366,-7.164422184,-2.41375865 -3578,D212K,0.01543215,0.060548834,0.017496813,-0.287656941,-1.616297616,-0.259782478,-0.085665975,0.116530274,0.073574531,-0.009545318,0.130642985,-0.220588097,0.255581722,-0.481692818,-0.093621063,-1.925426696,-1.307168536,1.754047212,1.416026293,-13.06921737,-12.46810815,-15.33546486,-13.26565019,-12.46157943,-11.81528421,-7.40848703,-2.701409002 -3579,D212M,0.137263212,-0.086212251,0.038204155,-1.461596856,-1.668718507,-0.009163435,0.099199208,0.175327215,-0.053298705,-0.214931398,0.042506896,-0.195329289,0.271737599,-1.51958781,-1.403605901,-2.118223649,-1.219213365,2.728808771,1.71184133,-14.82975552,-13.31465385,-14.11977993,-16.10816054,-15.73338357,-14.87279971,-8.098658947,-3.30049966 -3580,D212L,0.046244273,0.008860326,-0.145093688,-1.705730253,-2.467021641,0.07879159,0.044853788,0.047634758,-0.062271453,0.015396144,0.002324508,-0.278919765,-0.01126761,-1.875525992,-1.535934513,-2.54110862,-2.392934662,1.290198693,0.712634229,-15.45833308,-14.98532079,-15.20282879,-16.27529118,-16.58074883,-14.24747579,-7.626242221,-2.79669284 -3581,D212N,0.035139747,-0.039206784,0.178033156,0.242119395,-0.990291815,-0.117875655,-0.077573298,0.147852792,0.007094474,0.1741602,-0.252573767,0.104064944,0.252001368,0.143731633,0.340507157,-1.114107083,-0.866476547,0.735274658,1.351840776,-3.392107056,-3.599573128,-3.415153984,-2.788805466,-2.992302925,-4.164699776,-3.371026388,2.712400166 -3582,D212Q,0.425552231,-0.344646103,0.041474325,0.167395392,-1.083375828,0.024292058,0.056585736,0.794518726,0.134489356,0.032849679,-0.722141884,-0.024978517,0.107927166,0.071681701,0.263109083,-0.881859514,-1.284892141,0.594255728,1.353271186,-11.04012304,-11.5000378,-12.88237779,-9.906479477,-12.89137988,-8.020340279,-6.016136191,2.432267668 -3583,D212P,0.114636793,-0.098859339,0.056577642,0.017671171,-1.765575956,-0.183885842,0.042944517,0.186329069,0.073838314,0.0228327,-0.220551377,-0.03054781,0.143703093,-0.068259573,0.103601914,-1.747850278,-1.783301634,0.598780281,1.305529474,-13.52414235,-13.00648797,-13.50836068,-14.06186008,-13.66988313,-13.37411991,-6.5205254,-1.521214627 -3584,D212S,0.114062866,-0.070586778,0.088390618,0.14898735,-1.350442793,-0.145487229,0.067191857,0.160933875,0.044913541,0.067981996,-0.209155552,-0.013048455,0.189829691,0.015894369,0.282080331,-1.424875031,-1.276010554,0.609564021,1.318969811,-7.369889468,-7.559662476,-6.881417404,-8.116803871,-5.955345497,-8.336218094,-4.661864568,1.196876562 -3585,D212R,0.162783773,0.011739728,0.100975932,-0.625320886,-2.395898308,-0.063805173,0.067106779,0.258460766,0.059195639,0.020664386,0.00281507,0.020443164,0.1815087,-0.57446387,-0.676177901,-2.219024203,-2.572772412,1.692525312,1.336529886,-13.46444152,-14.46093436,-14.51072019,-14.31182519,-12.80359941,-11.23512846,-7.789945976,-2.719851725 -3586,D212T,0.236492311,-0.346922513,0.085650867,0.13004678,-1.432884767,-0.085642828,0.010008491,0.46297613,0.103938748,-0.018308037,-0.675536989,-0.003544914,0.174846647,0.027634907,0.232458653,-1.405633537,-1.460135996,0.955470413,1.348777149,-9.206155347,-7.810948502,-8.46278669,-11.06114219,-10.46770844,-8.228190918,-6.00124858,2.039979777 -3587,D212W,0.146557348,0.231281376,-0.093678712,-1.374198275,-1.970395552,0.054259111,0.151089018,0.142025678,0.050241887,0.176442962,0.286119789,-0.208444869,0.021087446,-1.634161032,-1.114235518,-2.23279687,-1.707994233,1.327769763,0.759061755,-15.83491338,-15.70733674,-16.17983297,-15.55259409,-16.4838647,-15.25093839,-9.887251498,-6.66660981 -3588,D212V,0.009144911,-0.076412805,0.036872162,-0.436430102,-1.849024683,-0.038434612,-0.009314019,0.02760384,0.050241887,0.005326944,-0.158152554,-0.05654399,0.130288314,-0.454231429,-0.418628775,-1.801055294,-1.896994071,1.702697449,1.437454069,-13.10027038,-11.85069236,-12.40362946,-14.75538599,-13.65257039,-12.83907369,-6.253690567,-0.074646801 -3589,D212Y,0.050627088,-0.208969286,-0.091051113,-1.770972205,-1.978093856,-0.022259684,0.020775839,0.080478337,-0.056091605,-0.088230511,-0.32970806,-0.147747029,-0.034355197,-1.423700871,-2.118243538,-2.323366705,-1.632821006,1.357390435,0.80884922,-14.87110054,-14.12619893,-16.9445811,-13.23498289,-15.62986945,-14.41987035,-8.999293042,-4.316477437 -3590,K213A,0.013259035,-0.178596377,-0.033302257,-0.099212993,-0.15013473,0.010471139,-0.032336336,0.058854406,0.003443649,-0.069134057,-0.288058697,-0.110557455,0.043952941,-0.185825858,-0.012600128,-0.085898772,-0.214370688,1.355691652,2.262272709,-5.529450345,-5.83233596,-5.244788048,-5.320082886,-5.891895622,-5.358149208,-3.583923176,-0.946880266 -3591,K213C,0.030701275,-0.155489534,-0.014017948,-0.063654057,-0.407447461,-0.016037957,0.009640707,0.051761843,-0.059139621,-0.116993838,-0.19398523,-0.085254808,0.057218913,-0.152884698,0.025576584,-0.293420349,-0.521474572,1.729856463,2.197669006,-9.205811482,-9.05472847,-8.584701477,-9.826750191,-9.748060173,-8.814817101,-7.736121212,-5.450530175 -3592,K213E,0.007355197,-0.141519327,-0.036711249,-0.102793969,-0.926966111,-0.027090994,-0.024548187,0.03925858,0.092541735,-0.072850159,-0.210188494,-0.116757481,0.043334984,-0.139621356,-0.065966582,-0.744045714,-1.109886507,1.597140633,1.744485133,-4.764894188,-5.450195244,-4.813034821,-4.5944561,-3.814447098,-5.152337677,-3.656970188,-0.757827198 -3593,K213D,-0.01676274,-0.106221292,-0.325919761,-1.631917997,-1.568932922,-0.092840669,-0.01461266,-0.01891282,0.078199049,0.024545883,-0.236988466,-0.253576779,-0.398262743,-1.487169811,-1.776666183,-1.696502003,-1.441363841,3.737037393,2.792058975,-7.606757166,-7.939579437,-7.386201324,-7.570781334,-7.667330933,-7.469892799,-6.045118872,-2.20709935 -3594,K213G,-0.011407198,-0.106674859,-0.015774903,-0.071999245,-0.72143042,-0.014105814,-0.049016886,0.02620249,-0.061659332,-0.040447127,-0.172902591,-0.073490296,0.041940491,-0.126312846,-0.017685644,-0.604697935,-0.838162905,1.583238906,1.798166183,-6.764265208,-7.520170097,-6.520429016,-7.200283257,-7.120248322,-5.460195351,-4.537027693,-2.468453078 -3595,K213F,-0.031636376,0.052864968,0.029665947,-0.006411961,-0.338193495,0.016994781,-0.056583441,-0.006689311,0.003190878,0.088918523,0.016811413,-0.04235224,0.101684134,-0.048531933,0.035708012,-0.320750943,-0.355636046,1.443998059,1.972220264,-9.910245035,-9.116238312,-9.718779839,-10.08842078,-9.614059418,-11.01372682,-7.162237796,-3.196131357 -3596,K213I,-0.055547307,-0.1818019,0.006204691,-0.111663109,-0.181811979,0.125034358,-0.120336027,0.009241413,0.017201592,0.004909915,-0.368513715,-0.046372306,0.058781687,-0.173510006,-0.049816211,-0.142917385,-0.220706572,1.404441966,2.15873831,-6.835935056,-7.253630142,-6.580871498,-7.843138924,-6.084800247,-6.417234467,-5.114658545,-2.097765929 -3597,K213H,-0.017596653,-0.143980558,0.00662126,-0.097257122,-0.247090884,0.016182172,-0.051418142,0.016224836,-0.016676794,-0.061928829,-0.226032286,-0.079076865,0.092319384,-0.148360775,-0.046153468,-0.176027594,-0.318154173,1.582208888,2.219333444,-5.230429819,-5.612887886,-4.48960363,-5.108792053,-5.642150063,-5.298715462,-5.565565725,-1.803216797 -3598,K213M,0.006604575,-0.159420197,0.010453651,-0.087290634,-0.081841882,0.016794286,-0.032583164,0.045792314,0.042558693,-0.045258125,-0.273582268,-0.040088252,0.060995553,-0.143273821,-0.031307446,-0.001696465,-0.161987298,1.231813699,2.464042643,-6.675834474,-6.421432083,-7.11862001,-7.143290604,-5.766055077,-6.929774597,-6.304795748,-3.081565898 -3599,K213L,0.025181031,-0.086228993,-0.028927476,-0.061253981,-0.065453657,0.015990427,0.008466267,0.041895795,-0.032267474,-0.057560413,-0.114897572,-0.091096869,0.033241918,-0.150545396,0.028037435,-0.048820808,-0.082086506,1.376014197,2.397550292,-5.935441881,-6.614023949,-6.496507126,-6.481012634,-4.81433976,-5.271325935,-4.674511744,-1.818038392 -3600,K213N,-0.089979663,-0.012241861,-0.012068771,-0.060090547,-0.186996305,0.086103208,-0.061134047,-0.118825278,0.085260904,-0.021159107,-0.003324615,-0.024470464,0.000332923,-0.033508853,-0.086672241,-0.136925546,-0.237067064,1.374667634,2.212412636,-4.832694496,-4.976177658,-4.616900757,-4.787181488,-4.922033508,-4.86117907,-4.501866209,-2.57157995 -3601,K213Q,-0.015278684,-0.076341173,-0.008285412,-0.055855318,-0.025008602,0.093710286,-0.047910956,0.017353589,-0.063216884,0.009541311,-0.162223657,-0.08714373,0.070572907,-0.082309431,-0.029401205,-0.007278849,-0.042738354,1.261582466,2.575244322,-1.978670702,-2.288034515,-2.142881973,-1.502769493,-1.984799904,-1.974867622,-2.508709203,0.117217461 -3602,K213P,-0.024254219,-0.052874837,-0.008872558,-0.748580952,-1.688237659,-0.030568129,-0.050218884,0.001710447,0.005628592,-0.054400883,-0.05134879,-0.081875193,0.064130078,-0.698163051,-0.798998853,-1.920896697,-1.455578621,1.88781494,1.446317176,-7.686393495,-8.61217141,-7.046088821,-8.342218857,-8.120347824,-6.311140564,-5.160410751,-1.688346359 -3603,K213S,-0.033554748,-0.112730859,-0.054055368,-0.085238998,-0.210462363,0.022463145,-0.049779733,-0.017329763,-0.053209941,-0.073735009,-0.151726708,-0.127771128,0.019660392,-0.146644745,-0.023833251,-0.195972498,-0.224952227,1.601294,2.249501175,-4.842875447,-5.221908379,-4.363752487,-5.97295192,-4.479227631,-4.176536819,-4.056906567,-1.16667883 -3604,K213R,0.004328584,-0.116185645,-0.017120396,-0.071587252,-0.106634552,0.032437935,-0.030872697,0.039529864,-0.003409626,-0.048121587,-0.184249703,-0.079529471,0.045288679,-0.113395347,-0.029779157,-0.043313758,-0.169955346,1.341771716,2.396205698,-2.109068019,-2.194177094,-1.511185623,-2.21711116,-2.704723122,-1.918143097,-2.253224271,-0.381619386 -3605,K213T,-0.003800431,-0.118149502,-0.042123153,-0.107751964,-0.342567648,-0.030608528,-0.034572454,0.026971593,0.00897727,-0.069201707,-0.167097296,-0.112034789,0.027788484,-0.15685553,-0.058648398,-0.317751508,-0.367383788,1.880909051,2.307628478,-4.364389534,-4.624284889,-3.988789436,-5.025066475,-4.835754486,-3.348052383,-3.786917955,0.536643838 -3606,K213W,-0.011197468,-0.110094559,-0.001042801,-0.086445343,-0.888566052,0.012762207,-0.047339049,0.024944114,-0.001451958,-0.025156854,-0.195032264,-0.04527788,0.043192279,-0.142812917,-0.030077769,-0.654186269,-1.122945835,1.475636515,1.739286291,-9.179618146,-8.804640762,-8.873613388,-9.950220657,-9.740918976,-8.528696945,-7.32498848,-4.776631026 -3607,K213V,-0.00819853,-0.13202287,0.002657291,-0.060309681,-0.120524299,0.025235333,-0.060945181,0.044548121,0.09733406,-0.040569378,-0.223476361,-0.074666039,0.07998062,-0.111723373,-0.008895989,-0.028620736,-0.212427862,1.437898184,2.544978656,-5.829983011,-6.673829964,-5.570718987,-6.193807259,-5.361053711,-5.350505135,-3.977251865,-0.850425307 -3608,K213Y,-0.014506305,-0.020949266,-0.016262078,-0.086895418,-0.370230613,-0.073908601,-0.033598522,0.004585913,0.076938397,0.043812637,-0.085711168,-0.081810806,0.049286651,-0.125739772,-0.048051063,-0.271190344,-0.469270881,1.585995444,2.1229941,-9.269448645,-8.94075174,-9.488941994,-9.553125488,-9.203682014,-9.160741989,-6.589973815,-2.487493147 -3609,V214A,0.103469719,-0.068066863,0.006739147,-0.041598242,-0.908327702,-0.09338211,-0.030418189,0.237357627,0.040009223,-0.005170654,-0.130963072,0.057627902,-0.044149609,-0.025906983,-0.057289501,-0.701972595,-1.114682809,0.692221699,1.391063252,-9.425958092,-11.22896339,-9.883159546,-9.222745834,-10.04943343,-6.745488251,-7.318838417,-3.204820328 -3610,V214C,0.128454407,-0.013210372,-0.006862655,-0.049724386,-1.214542094,-0.169356764,-0.049352138,0.306260952,0.086995111,0.060512208,-0.086932952,0.067333476,-0.081058785,0.009478475,-0.108927246,-1.335413716,-1.093670472,0.574288409,1.32060653,-14.14139774,-14.95517565,-13.69034844,-16.29258829,-14.51256151,-11.25631479,-8.042179142,-3.360444673 -3611,V214E,0.032427615,0.028456857,-0.013368413,-1.339504054,-2.109988078,-0.249985057,-0.088134327,0.152989556,0.097893049,0.072323169,-0.015409455,0.06617946,-0.092916285,-1.15709362,-1.521914488,-2.147511496,-2.07246466,2.159376204,1.44182232,-14.87652119,-17.13341249,-13.47086801,-16.36504733,-15.01292077,-12.40035735,-8.076400778,-3.297779613 -3612,V214D,0.196656827,0.008466308,-0.812161448,-1.635626594,-2.437506033,-0.181755814,-0.016722644,0.410036297,0.071093628,0.006510743,0.010421872,-0.793369638,-0.830953257,-1.628462546,-1.642790642,-2.567727899,-2.307284166,2.309067694,1.166332926,-14.09325238,-16.59904484,-12.59197234,-16.41132438,-12.82650069,-12.03741968,-6.62172962,-1.371819205 -3613,V214G,0.135999666,0.125165133,-0.002196157,-0.026279263,-1.505191289,-0.141613456,-0.021778916,0.293778247,0.085887579,-0.007253233,0.257583499,0.050881199,-0.055273513,0.020696567,-0.073255093,-1.733879823,-1.276502754,0.886105627,1.316093513,-14.08940724,-16.32003336,-13.74047269,-14.54197408,-14.23210054,-11.61245554,-8.0828271,-3.968211756 -3614,V214F,0.153119801,0.01782571,0.011464809,-0.201724934,-1.659114328,-0.11851063,-0.02972592,0.335965521,0.086995111,0.060206173,-0.024554754,0.098082042,-0.075152425,-0.114016968,-0.2894329,-1.982701247,-1.335527409,0.834207652,1.301325903,-12.9975101,-12.42374341,-12.2661206,-15.80780328,-13.42445661,-11.06542662,-6.61677546,-0.232627479 -3615,V214I,0.19241111,0.011660194,0.035006453,-0.043875689,-0.826021427,0.094481436,0.020544786,0.364277433,0.113342206,-0.06007017,0.083390558,0.017617798,0.052395107,-0.086320422,-0.001430955,-1.201677035,-0.450365819,0.969217636,1.374080915,-5.329401816,-5.090551567,-5.38318959,-5.521711868,-5.928378517,-4.723177536,-5.85885611,-1.10919555 -3616,V214H,0.164253492,-0.051812403,-0.045344207,-0.005308875,-1.462711156,-0.155865585,-0.048269779,0.376776763,0.121757217,0.036396937,-0.140021742,0.04080411,-0.131492524,0.078917297,-0.089535046,-1.723670917,-1.201751394,0.63065412,1.307369422,-15.09786283,-15.31813455,-12.79859322,-18.93543587,-15.74435675,-12.69279376,-7.774933309,-2.388515249 -3617,V214K,0.096475408,0.187257332,0.039240734,0.011664635,-1.159835975,-0.179984786,-0.054419976,0.247370792,0.098657249,0.079194421,0.295320243,0.105729867,-0.0272484,-0.047426376,0.070755646,-1.685661734,-0.634010216,0.617079404,1.308774054,-14.28457821,-14.45524024,-13.02119846,-15.77273214,-15.08670715,-13.08701306,-8.687305182,-4.468006979 -3618,V214M,-0.014596901,0.125501698,0.017432943,-0.114936464,-0.464651373,-0.121012611,-0.06604575,0.036851948,0.086607953,0.023636742,0.227366654,0.061555162,-0.026689276,-0.105057063,-0.124815864,-0.363081179,-0.566221566,1.510963913,1.967150126,-9.869516022,-9.845264664,-9.777039917,-9.475054024,-10.80744755,-9.442773956,-7.365516443,-3.022181369 -3619,V214L,0.092944827,0.017106408,-0.029466803,-0.007405749,-0.878103451,-0.113196462,-0.072729657,0.25861931,0.086214991,0.007615047,0.026597768,0.052232889,-0.111166495,0.048011224,-0.062822722,-0.872629788,-0.883577114,0.57354371,1.350739897,-6.695607883,-6.817189079,-7.052485435,-7.191440811,-6.801784851,-5.615139236,-5.341176435,-0.769377122 -3620,V214N,0.068592293,0.0000335,-0.033052461,-0.039471948,-1.332146477,-0.140118209,-0.064374276,0.201558861,-0.009943333,-0.01957715,0.019644071,0.033668362,-0.099773283,0.019130553,-0.098074448,-1.155663248,-1.508629706,0.844150143,1.359234761,-13.27218712,-14.75878712,-13.20789846,-15.36566426,-11.46681667,-11.56176911,-5.967597632,-1.252213472 -3621,V214Q,0.117702756,-0.010632579,-0.034547932,-0.075363309,-1.324416663,-0.138949954,-0.047897581,0.283303093,0.085732888,-0.013698759,-0.007566398,0.019345607,-0.088441471,-0.103763754,-0.046962863,-1.12575038,-1.523082945,1.052896566,1.399277726,-14.42652204,-15.88986733,-13.33045737,-15.43390808,-15.47941604,-11.99896137,-8.658005919,-3.79431225 -3622,V214P,0.211136504,-0.062503157,0.00463464,-0.110768725,-1.822061876,-0.154190749,-0.07221206,0.494485068,0.085030479,0.009944313,-0.134950626,0.056723919,-0.04745464,-0.042409115,-0.179128335,-1.738514865,-1.905608886,0.618209857,1.305969224,-13.01993227,-14.62165793,-10.9951878,-14.09270338,-12.68381815,-12.70629408,-6.686503849,-2.826672256 -3623,V214S,0.104075111,0.046297089,0.009632855,-0.057298864,-0.858990682,-0.090693064,-0.03481711,0.242967332,0.156909955,-0.053038651,0.145632828,0.076468354,-0.057202645,-0.019105701,-0.095492026,-0.950696575,-0.767284789,0.557047845,1.340162703,-11.28855412,-12.30323379,-11.07611539,-12.95657853,-9.981938995,-10.12490392,-6.399977597,-1.476953211 -3624,V214R,0.144320888,0.129899359,-0.002788639,-0.023635369,-1.47282212,-0.110314746,-0.04135916,0.330000936,0.074786414,0.017457398,0.242341319,0.062508309,-0.068085587,0.028402094,-0.075672832,-1.664344795,-1.281299445,0.622770105,1.309578704,-11.12683707,-11.56796969,-8.653530884,-11.8389836,-12.97199062,-10.60171056,-6.710822542,-2.305187905 -3625,V214T,0.09886749,0.096268712,0.018104244,-0.050957875,-0.246635617,-0.141841874,-0.014406514,0.212141494,0.086721687,-0.006858077,0.1993955,0.011131893,0.025076595,-0.013599675,-0.088316075,-0.19384383,-0.299427404,1.278892809,2.035531171,-5.464224016,-6.614370201,-4.595389771,-5.547096565,-6.94885067,-3.615412872,-4.890531344,1.550308435 -3626,V214W,0.071088932,0.087615692,-0.048183923,-0.287164663,-1.630367752,-0.115633716,-0.089192719,0.231370582,-0.021112692,0.026075148,0.149156236,0.050556217,-0.146924062,-0.095960555,-0.47836877,-1.689943777,-1.570791727,0.89689776,1.323301511,-14.1549763,-14.4475755,-13.13111323,-14.98182317,-13.9961329,-14.21823672,-7.827418092,-2.080117635 -3627,V214Y,0.161194391,-0.020889706,0.001662453,-0.240661438,-1.394818299,-0.065146164,-0.027519221,0.349908002,0.045804941,-0.026984495,-0.014794917,0.058307807,-0.054982901,-0.093495301,-0.387827574,-1.609997062,-1.179639536,0.723590018,1.316221535,-15.89596173,-15.99096864,-14.8390837,-19.35064449,-15.31967547,-13.97943635,-6.561899845,-0.82708322 -3628,A215C,0.023562944,-0.013440298,0.070899622,-0.681506457,-1.562565691,-0.094959911,0.075448236,-0.028322349,-0.016777615,-0.040324055,0.01344346,0.04469461,0.097104633,-0.629959857,-0.733053057,-2.079637179,-1.045494202,1.706779949,1.356186592,-10.98108636,-10.7267995,-12.53864843,-10.9396908,-10.19376569,-10.5065274,-6.966079927,-3.612432913 -3629,A215E,-0.042314189,-0.031344694,0.05873992,-0.437744951,-1.277329484,-0.132678514,-0.039097947,-0.045530431,-0.061269467,0.01547167,-0.078161057,0.157584051,-0.040104211,-0.410029072,-0.46546083,-1.626045037,-0.928613931,1.58480219,1.443726488,-10.44732098,-10.23297678,-11.39757707,-10.73320893,-10.41976097,-9.453081169,-7.190061016,-2.986214839 -3630,A215D,0.021827649,0.048333825,-0.834526107,-2.548238304,-2.091308436,-0.087369234,0.087024427,-0.04336913,0.063152507,0.076344507,0.020323142,-0.750874292,-0.918177921,-2.289931955,-2.806544652,-2.162117476,-2.020499395,1.539064424,0.535776915,-10.96955668,-10.88245868,-11.41843651,-11.22696829,-10.97648267,-10.34343727,-5.599776494,-0.736556308 -3631,A215G,-0.018948467,-0.002135481,0.045582685,0.005471771,-0.42454654,-0.089318816,0.000140548,-0.038037482,-0.033388117,0.013221221,-0.017492182,0.11695004,-0.025784671,0.002102707,0.008840834,-0.605429828,-0.243663252,0.819165363,1.443043045,-1.805307565,-2.155460876,-1.387775673,-2.232794205,-1.500159409,-1.750347664,-3.028826243,2.728144354 -3632,A215F,0.011324236,0.040074227,0.019395251,-1.433333779,-1.90507016,-0.038972508,0.129905689,-0.107257218,-0.049421677,0.09966261,-0.019514157,0.082018933,-0.043228431,-1.835673583,-1.030993975,-2.184980359,-1.62515996,0.696636482,0.678507996,-15.70080672,-15.17814287,-17.85481683,-15.74475196,-16.02049361,-13.70582833,-6.476577239,-2.007364541 -3633,A215I,-0.066446244,-0.041434983,-0.041298302,-2.2483158,-1.728916565,0.011638128,-0.054484942,-0.078407546,0.02914688,-0.075366804,-0.007503161,-0.063925507,-0.018671097,-2.05416869,-2.44246291,-1.801415476,-1.656417654,0.741039514,0.648722835,-11.90453562,-12.38342065,-13.84775199,-9.127097649,-12.03987695,-12.12453085,-7.139822205,-3.388983196 -3634,A215H,0.058867624,0.086784989,0.059561608,-0.31565459,-1.550710905,-0.103826555,0.05734369,0.060391558,0.02464171,0.077364732,0.096205246,0.127367317,-0.008244102,-0.212239683,-0.419069496,-2.041073784,-1.060348026,1.126547155,1.310877743,-13.65726951,-13.22027788,-14.31032695,-13.23880022,-12.87348872,-14.64345377,-6.508266357,-2.214085071 -3635,A215K,-0.07237293,0.018382935,0.019289137,-0.232453701,-1.870409311,-0.156284342,0.013972439,-0.158718298,-0.070237752,0.014033608,0.022732262,0.175299085,-0.136720812,-0.170822762,-0.294084639,-2.122189529,-1.618629093,0.989652087,1.299190247,-10.60752401,-11.37804474,-11.92988868,-9.31729174,-10.40679529,-10.00559961,-6.466888514,-2.477148377 -3636,A215M,-0.083894166,-0.059637207,0.154631948,-1.654397572,-1.50909235,-0.001800405,-0.053553797,-0.114234535,-0.037445239,0.150871567,-0.270145981,0.255705422,0.053558473,-1.772882753,-1.535912391,-2.122189529,-0.89599517,0.46910384,0.675823599,-12.01662661,-12.93240746,-14.94960044,-10.2733079,-12.26865303,-9.659164207,-7.460159527,-3.673600615 -3637,A215L,-0.07608236,-0.026271226,-0.108274838,-1.715166763,-2.504267698,0.070147608,-0.046537164,-0.105627556,-0.044833172,-0.024749331,-0.02779312,-0.100375259,-0.116174417,-1.66785485,-1.762478676,-2.971404136,-2.03713126,1.004346101,0.711978474,-13.96884615,-13.66697993,-17.44785216,-11.05689151,-14.45274866,-13.21975848,-7.647401964,-3.853275579 -3638,A215N,-0.109294524,-0.093327624,-0.060712781,-0.254367584,-1.684866444,-0.093299057,-0.055975707,-0.162613341,-0.055174006,-0.129790473,-0.056864775,0.071303468,-0.192729029,-0.148315421,-0.360419746,-1.48786236,-1.881870528,1.087760286,1.35943796,-10.59041736,-10.82385738,-11.98496444,-10.14614839,-8.913172142,-11.08394446,-5.145468497,-0.795278106 -3639,A215Q,0.047340227,-0.0168992,-0.006710984,-0.314523183,-2.01652056,-0.084776385,0.063424225,0.031256228,-0.07783799,-0.02274379,-0.01105461,-0.02375454,0.010332573,-0.368312165,-0.2607342,-2.236132882,-1.796908238,1.46450957,1.298843281,-10.94861969,-11.13708069,-11.75186317,-10.73216604,-10.39005102,-10.73193754,-6.135161754,-2.579041529 -3640,A215P,-0.016448781,0.043188129,0.044296746,-0.402080592,-1.5563334,-0.105342384,0.011024903,-0.043922464,-0.041923684,0.028240769,0.058135488,0.113108138,-0.024514647,-0.344278613,-0.459882571,-1.799528355,-1.313138445,1.450491059,1.382997745,-10.82438518,-11.11246517,-11.72284933,-10.33510964,-10.10185222,-10.84964953,-7.43306654,-3.673600617 -3641,A215S,0.019278083,0.014809262,0.075964766,0.073168095,-0.430107826,-0.102426409,0.061736669,-0.023180504,-0.028347981,0.07728183,-0.047663307,0.147774242,0.00415529,0.101583179,0.04475301,-0.55778291,-0.302432741,0.471449348,1.377525086,-5.247889478,-5.622802322,-5.626421837,-5.8872985,-4.520085388,-4.58283934,-3.983585836,0.407801727 -3642,A215R,-0.009886063,-0.035762112,0.036737023,-0.391303442,-1.642443334,-0.099139037,0.000167614,-0.01993974,-0.009045877,0.00727928,-0.078803504,0.119521445,-0.046047399,-0.331798869,-0.450808015,-1.858948095,-1.425938572,1.427829104,1.36357387,-12.20885485,-12.51672195,-12.92003445,-11.36292719,-10.84275133,-13.40183932,-6.441073371,-1.583870406 -3643,A215T,-0.007732292,-0.017173671,0.049608933,0.036441615,-1.243536899,0.081948903,0.057357656,-0.072822239,-0.033854659,0.013873085,-0.048220427,0.135876805,-0.03665894,0.067512689,0.00537054,-1.424183553,-1.062890245,0.485960664,1.313179273,-4.921768552,-5.408876144,-5.351601028,-5.982999657,-4.379944298,-3.485421631,-3.806535484,-0.906021656 -3644,A215W,-0.141502671,-0.10599767,-0.371469281,-1.896191995,-1.844041984,0.04633253,-0.091339664,-0.191665677,-0.116443662,-0.002095893,-0.209899447,-0.281158969,-0.461779593,-2.402971468,-1.389412521,-2.752278244,-0.935805724,0.927137957,0.446977464,-15.14971063,-14.23621075,-16.65526324,-14.77770676,-13.62365913,-16.45571325,-6.245466459,0.253314258 -3645,A215V,0.025584387,0.012245352,0.091730987,-0.806085664,-1.789833857,-0.030929356,0.069006949,-0.017838176,-0.020486978,0.024569803,-0.0000791,0.154989006,0.028472968,-0.787280574,-0.824890753,-1.784947361,-1.794720352,2.065604958,1.579293252,-9.204069029,-10.4230806,-10.54235567,-7.129606659,-9.45711795,-8.468184265,-6.91527874,-3.620203055 -3646,A215Y,-0.017559172,-0.053796611,0.060525633,-0.938298511,-2.06100181,-0.136957918,0.040844585,-0.075962929,0.007381498,0.008281279,-0.1158745,0.126236002,-0.005184737,-0.886540479,-0.990056543,-2.349790608,-1.772213011,0.832832689,0.78501274,-16.7007246,-15.35069089,-17.99366364,-17.34643345,-15.98576097,-16.82707406,-6.841454974,-1.49115889 -3647,G216A,-0.002891389,-0.006613634,0.000318167,-0.01109758,-0.310987193,-0.038288444,-0.032719569,0.026936792,-0.025029696,0.010363698,-0.023590965,0.023572599,-0.022936265,0.016845493,-0.039040653,-0.24666417,-0.375310215,1.228768595,1.90874274,-4.123762885,-3.940602737,-3.436713722,-3.426140205,-5.930458351,-3.884899406,-4.275803052,0.067327612 -3648,G216C,-0.011777837,-0.088251252,-0.006519942,0.013217701,-1.719736905,-0.09907958,-0.052794529,0.029238856,0.041375562,0.011062221,-0.187564725,-0.005469315,-0.007570569,0.026200743,0.000234659,-1.43248083,-2.00699298,0.569565963,1.315662319,-9.829597905,-11.20352809,-10.80347881,-8.38556945,-11.43682791,-7.318585258,-7.799637959,-3.881827976 -3649,G216E,-0.023045445,-0.036870406,-0.115991916,-0.024259738,-1.070069416,-0.13970165,-0.065499025,0.019408136,-0.148698421,-0.008425086,-0.065315725,-0.1940349,-0.037948931,-0.038235865,-0.010283611,-0.951825114,-1.188313717,1.061599243,1.43270767,-5.958552121,-6.413950066,-7.316737862,-5.349125526,-4.861704193,-5.851242958,-5.429977358,-0.791014809 -3650,G216D,0.006481269,-0.020265753,-0.031938171,-0.068140823,-1.101515398,-0.052325784,-0.001308344,0.014270882,-0.027285776,-0.013603513,-0.026927992,0.003292156,-0.067168498,-0.084767056,-0.05151459,-1.155964158,-1.047066638,1.02220432,1.38932045,-2.761740132,-2.667551071,-5.886782516,-2.29176622,-1.831496841,-1.131104012,-2.536583793,1.03013546 -3651,G216F,0.127374983,0.057259415,0.035869193,0.108238986,-1.497825789,-0.081839521,0.139418061,0.115331905,0.05605143,0.016685635,0.097833195,0.054808714,0.016929671,0.068867079,0.147610892,-1.311081595,-1.684569982,0.574924068,1.323095088,-9.735053555,-10.67012408,-10.90055251,-7.286821892,-13.1344863,-6.683282997,-6.430951118,-3.579345974 -3652,G216I,0.005978927,0.019712229,0.024611876,-0.011751027,-1.730204233,-0.035276787,-0.022130087,0.034087941,-0.0341252,-0.072345321,0.111769779,-0.015229153,0.064452905,-0.012845226,-0.010656828,-1.394692269,-2.065716196,0.602068069,1.319526861,-9.899021825,-10.94562433,-9.961905052,-8.179973145,-12.38141537,-8.026191223,-6.683863313,-3.23999094 -3653,G216H,0.005670523,-0.035751846,-0.022058478,-0.026433043,-0.843535431,-0.056283924,-0.00881639,0.020157436,-0.006005706,-0.013061298,-0.058442393,-0.011470922,-0.032646034,0.003425152,-0.056291238,-0.766524205,-0.920546657,0.763675241,1.39781194,-7.512663794,-9.715436852,-8.846412231,-5.664222801,-6.513981888,-6.823265198,-6.742360305,-1.530177956 -3654,G216K,-0.083295625,0.021156261,-0.065176612,0.020580032,-0.637357076,-0.106866673,-0.132387739,-0.034203511,0.187723549,-0.006122658,0.04843518,0.007167079,-0.137520302,0.034882581,0.006277482,-0.463603853,-0.811110298,0.81836707,1.490464867,-5.536546777,-7.198613495,-4.545164421,-5.202698227,-5.436162453,-5.300095291,-5.125700086,-0.144154606 -3655,G216M,-0.088814743,-0.169258512,0.014768267,0.043411705,-0.525735054,0.025537795,-0.109362803,-0.068266683,0.10271276,0.026526263,-0.365043287,0.05120459,-0.021668057,0.081337321,0.005486089,-0.309142236,-0.742327871,1.246214316,1.859798381,-8.505143004,-8.082379524,-8.747419228,-6.966036118,-10.62299767,-8.106882484,-6.461383479,-2.624256006 -3656,G216L,0.006812556,-0.069455419,-0.009667596,-0.017054919,-0.765563344,-0.060545044,-0.018732924,0.032358035,-0.032882583,-0.009582239,-0.129328598,0.017036847,-0.036372038,-0.012574592,-0.021535245,-0.640059523,-0.891067165,0.885102006,1.456194861,-7.234519986,-7.648190102,-8.041867706,-6.513365547,-9.087525932,-4.881650642,-5.298610443,-0.927385833 -3657,G216N,-0.055483692,0.061163385,-0.091181403,-0.032140943,-0.171467298,-0.01175052,-0.017639547,-0.093327836,0.038425467,-0.074356724,0.196683493,-0.083493984,-0.098868822,-0.078667118,0.014385233,-0.155600122,-0.187334473,1.427809532,2.213852115,-4.98125697,-6.371647972,-5.608445778,-4.266888374,-5.389413246,-3.269889481,-4.49872886,0.217256034 -3658,G216Q,0.06856371,-0.036985715,-0.000949386,0.03091792,-0.160168266,0.035652674,0.050177399,0.08695002,-0.106675867,-0.035959431,-0.038011999,-0.015933351,0.014034579,0.028942214,0.032893626,-0.190146979,-0.130189553,1.345179325,2.138992574,-5.363750354,-5.180051254,-6.117447678,-4.250453583,-5.481029366,-5.78976989,-5.162203505,-0.943110285 -3659,G216P,0.018835202,0.016392633,-0.012354637,-0.116471786,-1.499187483,-0.105826945,-0.00729243,0.044962833,0.001844382,-0.01607658,0.048861845,-0.024294195,-0.000415078,-0.08077118,-0.152172392,-1.748152333,-1.250222633,0.858667251,1.316704003,-8.806176485,-7.775528343,-7.824593826,-7.082954659,-13.36670285,-7.981102745,-5.359209936,-0.057788978 -3660,G216S,0.012239866,0.046390496,-0.006090613,0.007996046,-0.702568873,-0.07796723,0.008922055,0.015557676,-0.011791515,0.006466469,0.086314523,-0.017038311,0.004857085,0.00257987,0.013412221,-0.619317663,-0.785820083,0.935288536,1.482407248,-5.430268887,-6.125199554,-5.420694496,-3.904903984,-7.252644257,-4.447902145,-5.056076693,-1.14001398 -3661,G216R,0.018601533,-0.084044105,-0.018486799,0.001997235,-0.917942436,-0.053407795,-0.022573445,0.059776511,-0.012876648,-0.007234808,-0.160853402,-0.017980875,-0.018992723,-0.00842136,0.01241583,-0.759927791,-1.075957081,0.920282128,1.440236012,-5.578184041,-6.22638884,-5.660751129,-5.247268707,-4.796957878,-5.95955365,-4.165581816,0.354929573 -3662,G216T,-0.017409265,0.01468483,-0.029651074,0.005836657,-0.657379514,-0.082856638,-0.016353305,-0.018465224,-0.024851656,0.011719896,0.017649763,-0.022211206,-0.037090941,0.041773459,-0.030100146,-0.588283823,-0.726475205,0.502090185,1.377211586,-6.122869049,-6.512450737,-5.951319,-4.670941513,-8.399427589,-5.080206406,-4.719979186,-0.307093202 -3663,G216W,-0.054449038,-0.063948116,-0.046229828,-0.060131902,-0.921568061,-0.051959856,-0.072343248,-0.036554827,0.100573374,-0.049306752,-0.078589479,-0.01748621,-0.074973446,-0.041762574,-0.07850123,-0.697979322,-1.1451568,0.844221632,1.430358798,-11.01124455,-12.18530641,-10.73918853,-8.987266579,-13.41910608,-9.725355171,-7.578798344,-2.718290917 -3664,G216V,-0.026932497,-0.122627764,-0.037714493,-0.008556777,-1.553889303,-0.10530362,-0.082514931,0.028649937,0.009468926,0.016861991,-0.262117518,-0.013586282,-0.061842704,0.043027867,-0.060141421,-1.57385276,-1.533925845,1.081269012,1.352034995,-8.211486241,-9.392539841,-8.385290741,-6.367401382,-10.45328177,-6.458917473,-5.611465905,-1.929282358 -3665,G216Y,0.02549871,0.047522568,0.001946213,-0.032947085,-1.219190914,-0.100783052,0.005091311,0.045906108,-0.00112494,0.003353234,0.091691901,0.008737766,-0.00484534,-0.063925298,-0.001968872,-1.345843701,-1.092538127,0.918759923,1.350460801,-10.12734793,-12.94919798,-11.99416805,-7.097282097,-11.83584721,-6.760244347,-6.549859934,-2.926348264 -3666,P217A,-0.035104257,-0.016601721,-0.017223525,-0.003438406,-0.049668195,0.096735715,-0.021249645,-0.048958868,0.007413718,0.037359775,-0.070563217,0.035803087,-0.070250137,0.026097961,-0.032974773,-0.041158396,-0.058177994,1.265315663,2.496217769,-2.509097375,-1.322061172,-3.252903946,-2.847630005,-2.675889229,-2.447002525,-3.922539288,1.429935895 -3667,P217C,-0.03297198,0.013342314,0.055138156,0.01055482,-0.943436839,-0.010828974,-0.054952272,-0.010991687,0.014776965,0.053212812,-0.026528185,0.12290643,-0.012630118,0.044197337,-0.023087697,-0.792481887,-1.09439179,0.685969792,1.377361954,-9.18079593,-8.099236938,-9.852977585,-9.715291191,-10.13222026,-8.104253677,-8.335996679,-2.626039084 -3668,P217E,0.061009436,0.012347592,0.054936907,0.002771363,-0.294224134,-0.079384828,0.014580248,0.107438623,-0.053512758,0.054661856,-0.029966672,0.062797928,0.047075886,-0.008081664,0.013624389,-0.160516883,-0.427931384,1.332849414,2.129928596,-4.446299245,-2.992125366,-5.265222672,-6.406227058,-3.8163946,-3.751526527,-4.444484508,1.187247512 -3669,P217D,-0.02491113,0.078210747,0.021723402,-0.004205715,-0.149352214,-0.107600285,-0.05954381,0.00972155,0.061531624,0.08794054,0.068480954,0.083625885,-0.040179082,0.056678595,-0.065090024,-0.100276332,-0.198428096,1.420615056,2.563955177,-3.31890733,-1.644434273,-4.038151077,-6.087297119,-3.242029198,-1.582624985,-3.558855804,1.674903994 -3670,P217G,0.013693307,-0.044341877,-0.015918068,-0.007137341,-0.494440349,-0.021776674,0.010901204,0.016485409,0.045176263,0.003845163,-0.092528916,-0.000115875,-0.03172026,-0.006212095,-0.008062586,-0.366362474,-0.622518223,1.061542465,1.65479138,-3.770486748,-2.233006462,-4.886214737,-5.027651802,-4.401579315,-2.303981422,-5.22758833,0.579268462 -3671,P217F,-0.052804572,-0.045092675,-0.065338427,-0.054681412,-1.509183144,-0.00678853,-0.06963878,-0.035970364,-0.057063154,-0.06341561,-0.026769739,-0.077993005,-0.052683848,-0.044978834,-0.064383989,-0.941737365,-2.076628922,0.929104963,1.40094192,-10.6266267,-10.06115308,-11.17402383,-10.56356091,-11.85814646,-9.476249237,-8.004255367,-3.06238992 -3672,P217I,-0.013264945,0.087849096,-0.018662892,-0.020307091,-1.350092088,-0.03216553,0.015358526,-0.041888415,0.06901248,0.109670733,0.066027458,-0.054743068,0.017417284,-0.024011033,-0.016603149,-1.119493653,-1.580690523,0.724731677,1.347417956,-10.67070695,-9.136974487,-13.18514881,-10.87821847,-10.57610178,-9.577091225,-8.59648343,-3.85100613 -3673,P217H,0.044303155,-0.02325768,0.020875202,0.004635463,-0.221030842,0.03661518,0.043755385,0.044850924,0.031148996,0.018377956,-0.064893315,0.025157898,0.016592505,-0.015666664,0.024937589,-0.212436347,-0.229625336,1.557634929,2.226564484,-6.402804721,-5.672334915,-7.255904861,-7.187190384,-6.970301483,-4.928291962,-5.32369567,1.125742479 -3674,P217K,0.062003447,0.08493882,0.020864521,0.061836518,-0.007076838,0.087539758,0.093035603,0.03097129,-0.005324185,0.084030467,0.085847173,0.038888088,0.002840953,0.127049771,-0.003376736,-0.008684155,-0.00546952,1.321668002,2.76236175,-4.212065199,-2.735831711,-5.878951134,-4.491291534,-4.05868399,-3.895567627,-4.407592617,1.256034733 -3675,P217M,-0.096982015,-0.054837605,-0.009540184,-0.111076562,-0.156304504,0.054080464,-0.114283146,-0.079680884,0.007554477,-0.012247672,-0.097427537,0.099553434,-0.118633801,-0.020604784,-0.201548339,-0.010420327,-0.30218868,1.543610422,3.106887046,-8.48229604,-7.200363914,-10.06263823,-9.163198906,-8.02516124,-7.960117912,-6.955173967,-2.414323691 -3676,P217L,-0.02001265,-0.025505335,-0.0122177,-0.006768483,-0.541115992,0.034532629,-0.017922259,-0.02210304,-0.000425804,0.02809577,-0.079106439,-0.000674998,-0.023760402,0.000694407,-0.014231373,-0.420740518,-0.661491465,0.939392255,1.563063857,-8.280118896,-7.175396156,-9.614958923,-8.850492302,-8.040279785,-7.719467316,-7.12814073,-1.350654129 -3677,P217N,-0.07331183,0.020165346,-0.060433929,-0.031556496,-0.131099892,-0.069997816,-0.019660865,-0.126962794,0.034250374,-0.01054891,0.050879602,0.018582622,-0.13945048,0.020972354,-0.084085345,-0.132451922,-0.129747861,1.347976698,2.242472497,-3.286205981,-1.939479576,-3.857469818,-3.670100899,-4.168489319,-2.795490295,-4.199061503,1.421521764 -3678,P217Q,-0.01108221,-0.011806349,0.023728605,0.00961528,-0.143022174,0.022935068,-0.028996732,0.006832312,0.022993202,0.03311488,-0.056727578,0.042060692,0.005396518,0.031364849,-0.012134289,-0.07008448,-0.215959867,1.414904449,2.54082215,-4.848964154,-3.819085587,-5.977115891,-5.965240929,-4.59165657,-3.891721794,-5.274300252,0.645187404 -3679,P217S,0.009533892,-0.004407541,-0.017485182,0.039209529,-0.300363106,-0.036414129,0.023960691,-0.004892908,0.000833784,0.02175942,-0.030574502,-0.013075454,-0.02189491,0.055632081,0.022786977,-0.227974003,-0.372752209,1.175745851,1.950669638,-3.674477931,-2.641335014,-4.164132088,-3.84758519,-4.298399139,-3.420938225,-4.906253993,1.033611012 -3680,P217R,0.005384054,-0.064369505,-0.00927909,0.006105439,-0.512200053,0.045422297,0.003550502,0.007217605,-0.00388548,0.024073706,-0.152812715,0.002552824,-0.021111003,0.01958839,-0.007377512,-0.364083057,-0.660317049,1.059478962,1.662455542,-6.319127513,-4.357751511,-8.642395096,-8.541373199,-5.643384094,-4.410733665,-7.003257388,0.825908596 -3681,P217T,-0.012296522,0.06112032,0.010158154,0.024849086,-0.193910919,-0.016709769,0.006360863,-0.030953907,0.036944433,0.06377154,0.0584691,0.03635239,-0.016036083,0.030984874,0.018713298,-0.182900399,-0.204921439,1.38706504,2.153287332,-5.020718037,-3.379785507,-6.733288719,-5.398737396,-4.386834358,-5.204944206,-3.879840028,1.272994125 -3682,P217W,-0.002458467,-0.058029986,0.016268091,-0.00227249,-1.924774941,0.01720804,0.005117292,-0.010034226,-0.048123873,0.054608137,-0.170668108,0.039542449,-0.007006268,0.042294497,-0.046839477,-1.600219032,-2.249330849,0.652179761,1.316017337,-10.38073444,-8.452413818,-11.27014333,-11.69978212,-11.45692411,-9.024408836,-7.972537725,-2.626039029 -3683,P217V,0.064024997,-0.014537332,0.032537464,0.024850381,-0.281510655,-0.009649058,0.026728989,0.101321004,0.032116244,0.010234696,-0.03930936,-0.021308213,0.08638314,0.02730562,0.022395141,-0.157132265,-0.405889044,1.282950559,2.134169417,-8.920625391,-7.402179199,-11.73463029,-9.305690056,-8.63942498,-7.521202431,-7.082447889,-1.857570271 -3684,P217Y,0.047043569,0.029349611,0.034346435,-0.018649919,-1.044703536,-0.040709913,0.046445674,0.047641463,-0.046219871,0.014122765,0.044576457,0.030737741,0.037955128,-0.045520272,0.008220435,-0.809746545,-1.279660527,0.642309334,1.365737651,-9.076290976,-8.287556992,-9.778807709,-9.126171005,-10.49586242,-7.693056755,-6.740915825,-0.886155062 -3685,L218A,-0.034110833,-0.04109114,-0.034370896,-1.573596662,-2.157489669,-0.074077556,-0.066592123,-0.001629543,0.004778844,-0.040118443,-0.042063837,-0.049298726,-0.019443066,-1.461041467,-1.686151857,-2.022505783,-2.292473555,2.715898052,1.784616108,-11.82753091,-11.06658401,-11.90531981,-12.95222167,-14.47699582,-8.736533218,-6.877561983,-2.870603811 -3686,L218C,-0.086500158,-0.020835752,-0.07063399,-0.967747313,-1.887985664,-0.030762592,-0.103414422,-0.069585894,0.126250374,-0.045633214,0.003961711,-0.068732608,-0.072535371,-0.517643752,-1.417850874,-2.071440627,-1.7045307,1.691891293,1.367684752,-11.04510899,-8.708488396,-11.26071796,-12.6633233,-13.45234252,-9.140672752,-6.760660675,-2.497484833 -3687,L218E,-0.036320597,-0.022625097,-0.680249856,-1.780352837,-2.809141168,-0.142126885,-0.068498151,-0.004143043,0.042494168,-0.028148711,-0.017101483,-0.715149521,-0.645350191,-1.891297807,-1.669407867,-2.656882106,-2.96140023,1.972674251,0.867606363,-14.6491341,-14.14951814,-13.68281259,-16.15465314,-17.98563412,-11.27305253,-8.236131653,-2.817413684 -3688,L218D,0.023469783,-0.070989311,-0.091439376,-1.788551701,-1.649850489,-0.128680764,0.034667892,0.012271674,0.106759286,-0.048510596,-0.093468025,-0.083999511,-0.09887924,-1.671686814,-1.905416588,-2.062454903,-1.237246074,1.004475226,0.712251304,-17.48504528,-15.11093855,-20.59971222,-19.56408167,-18.87847422,-13.27201973,-8.78994063,-3.482839062 -3689,L218G,-0.032382493,-0.04383445,-0.034613908,-1.504824648,-2.040364951,-0.112232983,-0.044399197,-0.020365788,-0.017982776,-0.057942888,-0.029726011,-0.052680339,-0.016547477,-1.396199891,-1.613449405,-2.198213455,-1.882516446,0.932425368,0.734638385,-14.0077537,-13.32759182,-12.2119784,-16.0877579,-17.87385423,-10.53758617,-7.04881436,-1.939826798 -3690,L218F,-0.09902433,-0.047278677,-0.023279547,-1.727729377,-2.233060674,-0.075599776,-0.085095553,-0.112953106,-0.03698062,-0.048462299,-0.046095054,-0.005057956,-0.041501137,-1.485065528,-1.970393226,-2.301802349,-2.164318999,0.952540715,0.730044196,-9.634879424,-8.110473755,-10.8925898,-10.92467815,-9.719133072,-8.527522339,-8.101519885,-4.082017397 -3691,L218I,-0.010461264,-0.0156067,-0.034513271,-0.21312514,-1.350570111,-0.053618331,0.021849952,-0.042772479,-0.129267703,-0.112977494,0.081764095,-0.102610519,0.033583978,-0.168047427,-0.258202852,-1.829882288,-0.871257933,1.246472262,1.341526937,-8.733722961,-8.553791061,-7.460346214,-10.24869703,-9.959099205,-7.446681297,-8.163864795,-2.403246097 -3692,L218H,-0.002556199,-0.027350066,-0.169681127,-1.717817127,-2.623540895,-0.075591185,0.005930673,-0.011043071,0.060854177,-0.058560371,0.00386024,-0.225765347,-0.113596907,-1.726155729,-1.709478525,-2.412558781,-2.834523009,1.273200749,0.735906377,-13.53327335,-11.32437807,-14.51921588,-16.22522029,-13.82624717,-11.77130534,-8.242263906,-4.099427563 -3693,L218K,-0.039520723,0.005233643,-0.777621553,-1.821604501,-2.560616507,-0.117794104,-0.012516916,-0.06652453,-0.108171992,-0.053374829,0.063842114,-0.918312556,-0.636930549,-1.673197405,-1.970011596,-2.489934226,-2.631298787,2.628416573,1.358083519,-9.306860046,-10.09038832,-7.127389343,-9.932597824,-10.61110559,-8.772819153,-6.032343239,-0.432725376 -3694,L218M,0.01391873,0.009697374,0.02547685,0.036105148,-0.362441867,0.005535481,0.036833676,-0.008996216,-0.036881454,0.018470811,0.000923937,0.023573546,0.027380153,0.106301889,-0.034091593,-0.285364431,-0.439519302,0.884123673,1.641405735,-5.288082295,-5.626445381,-4.875713234,-5.518775101,-5.999373917,-4.420103844,-6.539617073,-2.159175191 -3695,L218N,-0.034380883,-0.033071571,-0.102963072,-1.79807484,-2.612333267,-0.073462162,-0.038265399,-0.030496366,0.027045408,-0.09914542,0.033002279,-0.104221927,-0.101704217,-1.879010546,-1.717139134,-2.440474862,-2.784191671,1.076361799,0.690782792,-12.96661017,-12.19876714,-10.3621698,-16.52243047,-15.24110163,-10.50858183,-8.444065399,-4.223385462 -3696,L218Q,-0.036080357,-0.063033365,-0.174928438,-1.738611119,-2.130320525,-0.146720906,-0.064043327,-0.008117387,0.07222351,-0.083389089,-0.04267764,-0.163658453,-0.186198422,-1.660807816,-1.816414421,-2.523302128,-1.737338922,1.135433797,0.727571482,-11.5166414,-12.12877222,-10.07949226,-13.47332497,-12.17932923,-9.72228833,-6.399284082,-2.655514704 -3697,L218P,-0.047777103,-0.013548348,-0.008879468,-1.565164754,-2.095105062,-0.095478639,-0.060118954,-0.035435251,-0.013532196,-0.024763436,-0.00233326,-0.016297319,-0.001461616,-1.530617409,-1.599712099,-2.23820976,-1.952000364,1.024458581,0.731841463,-14.18916834,-13.25152785,-13.990549,-16.03448138,-16.88298299,-10.78630045,-8.577109008,-4.509438339 -3698,L218S,-0.03369373,-0.009907581,-0.191060209,-1.784374889,-3.079750314,-0.116096276,-0.048959462,-0.018427997,0.00037849,-0.058622871,0.038807709,-0.201259656,-0.180860762,-1.687409599,-1.881340178,-2.819416854,-3.340083773,1.21515909,0.732844825,-10.80714834,-10.73514618,-8.804790703,-13.09964452,-13.14909433,-8.247065994,-6.825377677,-1.702308556 -3699,L218R,-0.032774274,0.007219869,-0.986279242,-2.20290449,-2.751810874,-0.058135224,-0.039314664,-0.026233884,-0.004905424,-0.020281338,0.034721075,-1.021127935,-0.951430548,-2.223170816,-2.182638163,-2.562786382,-2.940835366,0.800323799,0.13086038,-8.827390225,-8.142323524,-6.872507912,-10.28778353,-9.699333244,-9.135002914,-5.410978428,1.077462831 -3700,L218T,0.014576709,0.004411021,-0.006654996,-1.54755897,-2.242838135,-0.132305396,-0.041012009,0.070165426,-0.056035789,0.000589628,0.008232413,-0.029985551,0.01667556,-1.426673574,-1.668444366,-2.445515087,-2.040161183,0.618889537,0.705014533,-8.521758916,-7.709965286,-7.067710114,-9.833602615,-12.13737011,-5.860146454,-6.582300276,-2.163665871 -3701,L218W,0.000904237,0.039769528,-0.687777765,-1.865651239,-2.414557624,-0.114498631,-0.029071924,0.030880398,0.028070915,0.046746039,0.032793017,-0.754487168,-0.621068361,-1.764644523,-1.966657954,-2.502200098,-2.326915149,2.105316931,0.987067598,-11.69260705,-10.13171888,-12.73180041,-14.46376572,-9.942488617,-11.19326164,-8.169695392,-2.92512573 -3702,L218V,-0.002427662,-0.041385094,-0.004195211,-0.955977204,-2.045548314,-0.09399794,-0.023520269,0.018664945,0.01769726,-0.076660256,-0.006109931,-0.05601664,0.047626219,-0.650411737,-1.261542671,-2.040301576,-2.050795052,1.855945807,1.413268544,-8.662192828,-7.526389,-7.015631218,-11.31917018,-10.86951732,-6.580256424,-7.282305222,-2.482387337 -3703,L218Y,-0.010062209,0.063228564,-0.492221186,-1.8373467,-2.606993534,-0.066623058,-0.015345484,-0.004778934,-0.001323456,0.026582636,0.099874492,-0.378843765,-0.605598606,-1.804869525,-1.869823874,-2.445515087,-2.76847198,1.500276084,0.761652785,-12.54110254,-9.321149979,-14.70205543,-14.84520763,-12.14179208,-11.69530758,-7.377820467,-2.578954384 -3704,L219A,0.025114333,-0.008984792,-0.018802827,-1.538832679,-1.965542709,-0.036415291,0.02520131,0.025027356,-0.023270697,0.00562387,-0.023593453,-0.077657844,0.040052191,-1.528219476,-1.549445881,-2.270002019,-1.661083398,0.834185235,0.711602171,-8.009758572,-8.677106422,-8.326057838,-8.424227821,-6.589509422,-8.031891357,-5.638754157,-3.088819925 -3705,L219C,-0.006903001,-0.015711658,0.028391857,-1.638408679,-2.727414578,-0.072491812,0.004820308,-0.018626309,0.011960538,-0.01051578,-0.020907535,0.015878928,0.040904786,-1.585055323,-1.691762035,-2.814954504,-2.639874652,0.149696623,0.680536476,-10.54020282,-11.13402138,-10.37099089,-11.03966244,-10.07617941,-10.08016,-8.973277603,-9.972551682 -3706,L219E,0.077663406,0.012207131,0.06259669,-1.638387124,-2.438363166,-0.006254776,0.076460533,0.078866279,0.013357341,-0.020126717,0.044540979,0.001250469,0.123942911,-1.789854421,-1.486919826,-2.292754875,-2.583971457,0.64276054,0.679151458,-11.66728859,-12.15368471,-11.47877463,-12.14192462,-11.10679507,-11.45526392,-9.016060319,-10.11260904 -3707,L219D,0.070535704,0.060995399,0.056442419,-0.983352932,-2.447858334,-0.066191186,0.049082485,0.091988922,0.050061317,0.080793431,0.041197367,-0.004992255,0.117877092,-0.87992501,-1.086780853,-2.711884183,-2.183832484,0.687455498,0.761446911,-12.01517683,-12.16334091,-12.48077892,-12.48298676,-11.48049861,-11.46827892,-9.016060319,-10.11260885 -3708,L219G,0.004724535,0.011219492,-0.255226823,-1.669207766,-2.710439912,-0.006162322,0.007365132,0.002083938,-0.011992107,-0.008269571,0.030708554,-0.332197972,-0.178255674,-1.636395956,-1.702019575,-2.692664476,-2.728215348,1.530181225,0.807469765,-10.81862116,-11.05822324,-11.30454337,-11.34955824,-10.05514713,-10.32563382,-7.064636384,-5.079969338 -3709,L219F,-0.038369486,-0.225249692,0.021873568,-0.00622174,-0.542806621,-0.107124913,-0.06171225,-0.015026722,0.063790118,-0.024716754,-0.425782629,0.019894568,0.023852567,-0.017452874,0.005009395,-0.382050629,-0.703562612,0.665073662,1.473064635,-2.997163843,-3.777477005,-2.770237419,-3.33406266,-2.904766624,-2.199275505,-2.695602487,-2.251337595 -3710,L219I,0.186191806,-0.300584627,0.077223272,0.050990683,-0.341983998,-0.006621487,0.103516173,0.268867438,-0.007053638,-0.042073852,-0.559095401,0.000808906,0.153637637,0.020273711,0.081707654,-0.016450487,-0.667517508,1.281800064,2.632016107,-1.586831035,-2.163008598,-1.953607414,-1.644639015,-1.068472404,-1.104427742,-1.783438242,-0.184026989 -3711,L219H,0.015948308,-0.044011121,0.013208633,-1.613842953,-2.192562432,-0.007528433,0.03084621,0.001050405,0.0000732,-0.020753857,-0.067268384,-0.040132671,0.066549937,-1.619158194,-1.608527712,-2.343907397,-2.041217466,0.708491084,0.698463503,-10.88346806,-11.94007615,-10.4305128,-10.91085563,-10.43862392,-10.69727181,-9.016060319,-10.1126085 -3712,L219K,-0.000560749,0.036116381,-0.010258717,-1.589377857,-2.040645811,-0.047319221,-0.030744197,0.0296227,0.033994662,0.021968932,0.050263829,-0.031448619,0.010931185,-1.492204166,-1.686551547,-2.421073352,-1.660218269,0.947622538,0.725118061,-11.50395784,-11.92727293,-11.41548264,-11.83239072,-10.68977407,-11.65486882,-9.016060319,-10.11260934 -3713,L219M,-0.055092916,0.091256863,0.004683021,-0.03230548,-0.595117345,-0.052413139,-0.075580596,-0.034605236,0.003610038,0.025390306,0.15712342,0.01034455,-0.000978508,-0.053000939,-0.011610021,-0.411566729,-0.77866796,1.118636719,1.671303432,-4.106352252,-4.575011856,-3.647066963,-5.772195839,-3.147541168,-3.389945435,-5.088416564,-2.674381237 -3714,L219N,-0.026094242,-0.008409513,0.000884204,-1.480173015,-2.58579938,-0.11456295,-0.02842621,-0.023762274,0.00857715,-0.040091615,0.02327259,-0.094516422,0.096284829,-1.366591583,-1.593754446,-2.693400777,-2.478197983,0.998709805,0.747776584,-11.43184657,-12.04677184,-11.40608025,-11.70255564,-10.77312357,-11.23070152,-9.016060319,-10.11260922 -3715,L219Q,-0.008193556,-0.031420794,0.013768855,-1.595699207,-2.141130018,0.011933809,0.023340043,-0.039727155,0.046714232,0.013327199,-0.076168787,-0.04167621,0.069213919,-1.477364804,-1.714033609,-2.059446503,-2.222813532,0.79896248,0.718172379,-11.29410985,-11.58817986,-11.34909618,-11.81362836,-10.32032532,-11.39931953,-9.016060319,-10.11260922 -3716,L219P,0.013242688,-0.004430684,0.006998325,-0.75809352,-1.848450853,-0.049241707,0.03929659,-0.012811214,-0.017842374,-0.022713587,0.013852219,-0.058634613,0.072631263,-0.631824354,-0.884362686,-2.007276727,-1.689624978,1.803454184,1.407668247,-11.31121702,-11.93466834,-11.2534119,-11.67540392,-10.7752403,-10.91736063,-8.415656587,-8.087553656 -3717,L219S,0.043221262,-0.039701381,-0.028592395,-1.482414777,-2.416982134,-0.058391141,0.019563272,0.066879251,0.018400003,-0.006360436,-0.073042325,-0.073626212,0.016441423,-1.382934215,-1.581895339,-2.331108556,-2.502855711,0.668121338,0.710430695,-8.50593278,-9.749859116,-7.973522919,-8.901148376,-7.330169579,-8.574963913,-6.286328004,-4.423684472 -3718,L219R,0.005178914,-0.005646663,-0.002784307,-1.527060225,-2.207771293,-0.033938708,0.026285284,-0.015927457,-0.008137551,-0.051792031,0.040498705,-0.094909626,0.089341013,-1.540659265,-1.513461184,-2.312990728,-2.102551858,1.003961743,0.728026602,-12.00641646,-12.04749477,-12.39005212,-12.37266973,-10.99386008,-12.22800562,-9.016060319,-10.11260937 -3719,L219T,-0.012405284,-0.005184318,-0.006395438,-1.706693914,-2.383980324,-0.044723892,0.026711078,-0.051521645,-0.015167296,-0.035875131,0.025506496,-0.078400714,0.065609838,-1.617647603,-1.795740224,-2.400388753,-2.367571894,0.797848496,0.703131034,-9.196696576,-9.462819077,-9.274487846,-10.28830209,-7.983264557,-8.974609306,-6.751724866,-5.581652508 -3720,L219W,0.002160145,0.034672722,0.056318645,-1.555166321,-2.493348556,-0.108352581,0.020354569,-0.01603428,0.015167092,-0.001160721,0.070506164,0.030186677,0.082450613,-1.444493191,-1.665839451,-2.146965999,-2.839731112,0.63465847,0.704948481,-10.10031437,-10.6553564,-9.915016144,-10.63860181,-9.731742073,-9.560855408,-9.016060319,-10.1126096 -3721,L219V,0.028720486,0.006954276,0.003082763,-0.016339212,-0.227873442,0.01576461,0.049244077,0.008196894,0.001345826,-0.034856385,0.048764937,-0.07142853,0.077594056,-0.018436554,-0.014241869,-0.213467587,-0.242279296,1.452381735,2.093390515,-4.535940295,-4.432747101,-5.072064766,-4.378806267,-3.875861496,-4.920221848,-4.52149629,-2.536753793 -3722,L219Y,0.059062579,-0.289654768,-0.226921464,-2.084155787,-2.240510973,-0.056944697,0.002024261,0.116100896,-0.07191303,0.01834096,-0.597650496,-0.33592936,-0.117913568,-2.011024055,-2.157287518,-2.1159845,-2.365037446,1.395104458,0.70019404,-7.808930043,-9.048284973,-7.205372299,-7.732498329,-7.603923355,-7.454571259,-7.182748421,-6.757518222 -3723,R220A,-0.09285731,0.014737218,-0.037112376,-1.004084057,-2.198580773,-0.013844038,-0.066982252,-0.118732368,-0.055237692,-0.005372734,0.034847169,-0.040259943,-0.033964809,-0.760250072,-1.247918042,-2.09094906,-2.306212486,1.943661475,1.417269131,-10.02796299,-9.529456985,-8.54125238,-11.87333527,-8.87186245,-11.32390787,-5.208183325,-1.612165964 -3724,R220C,-0.021991661,-0.044092083,-0.339312332,-1.255551449,-1.843028038,-0.024991964,-0.002779929,-0.041203392,-0.01489921,0.02879867,-0.116982836,-0.241969721,-0.436654942,-1.06501984,-1.446083057,-1.538685226,-2.14737085,3.529698443,2.808826659,-14.10118165,-13.41988519,-12.92780442,-14.92955727,-13.2756386,-15.95302277,-9.277171266,-7.078200245 -3725,R220E,0.051373451,0.071724301,-0.061008012,-1.736818518,-2.427769743,-0.021486,0.056896403,0.045850499,-0.046507304,-0.022321382,0.165769983,-0.146327155,0.024311132,-1.470967531,-2.002669504,-2.240523273,-2.615016212,1.156099235,0.758528581,-12.92887119,-12.8564987,-11.42043869,-14.10168571,-12.88538663,-13.38034622,-7.464895001,-4.200399265 -3726,R220D,0.104957616,0.077611577,-0.238104139,-1.73191135,-2.689181867,-0.018409437,0.125500133,0.084415098,-0.010944162,0.028308392,0.126914761,-0.261883032,-0.214325246,-1.973515823,-1.490306877,-2.839981578,-2.538382155,1.204528733,0.684414256,-14.10282911,-13.35984666,-13.16314949,-14.75838268,-13.64662033,-15.58614641,-8.195634095,-5.190393153 -3727,R220G,0.032107894,0.069486716,0.02790633,-1.430734526,-1.927532395,-0.081976998,0.041578397,0.022637391,-0.050108313,0.023689366,0.115284065,-0.008315852,0.064128512,-1.350300421,-1.51116863,-2.09465673,-1.76040806,2.380394008,1.533726088,-10.78065263,-10.94027393,-9.785020874,-12.03800871,-10.06550986,-11.0744498,-6.224211257,-2.940466789 -3728,R220F,0.004401698,0.039505688,0.044299042,-1.747084841,-2.505385354,-0.010843353,-0.030420885,0.039224281,-0.060000245,0.105202945,-0.026191569,0.004337067,0.084261017,-1.438668815,-2.055500866,-2.606164566,-2.404606141,0.537557446,0.700131142,-14.62434725,-13.50058071,-12.86116742,-14.14083429,-13.24637798,-19.37277585,-9.087505455,-6.670060691 -3729,R220I,0.032712336,0.06137694,-0.060326186,-1.622727732,-2.353178169,-0.011966478,0.023220522,0.04220415,-0.041710966,0.012952749,0.109801131,-0.124575115,0.003922744,-1.646762242,-1.598693221,-2.735076747,-1.971279591,0.948502581,0.708796263,-12.60486958,-11.82774434,-10.92513641,-14.18748773,-11.31427025,-14.76970917,-7.333559906,-3.971267673 -3730,R220H,0.009439016,0.029295278,0.02892705,-1.184329313,-1.476075347,-0.085799325,-0.01086206,0.029740091,-0.03464855,0.048042538,0.010548018,0.029431357,0.028422742,-0.879343997,-1.489314629,-1.522136233,-1.43001446,2.789902573,2.197331546,-8.23991129,-8.997309113,-7.65426931,-7.93286705,-7.744955032,-8.870155945,-6.470422817,-4.564920165 -3731,R220K,-0.015958948,0.022408149,-0.001500778,-0.036218533,-1.795858879,-0.091517138,-0.014405971,-0.017511924,-0.001701507,0.064242208,-0.01942591,0.03902542,-0.042026976,0.045237934,-0.117674999,-1.748512618,-1.84320514,0.540058444,1.304169708,-6.765942548,-5.88325724,-6.381748032,-7.583916618,-6.957897491,-7.022893356,-5.612307782,-1.321613255 -3732,R220M,0.05056911,0.000683304,-0.0110996,-1.557312971,-2.584173075,0.014297127,0.066382843,0.034755376,0.040326907,0.033201776,-0.031835168,-0.051865448,0.029666248,-1.719267269,-1.395358672,-2.710671761,-2.457674389,0.724942666,0.687667944,-13.69249079,-12.84961121,-12.72874238,-16.00241448,-11.92665916,-14.9550267,-8.613598877,-6.503826029 -3733,R220L,-0.003707532,0.02374803,-0.062214075,-1.473826394,-1.572457607,-0.039784775,-0.002244845,-0.005170219,-0.036002499,0.069972976,-0.022476917,-0.077417239,-0.047010911,-1.339930191,-1.607722597,-1.671282744,-1.473632469,3.31043286,2.469546478,-11.1816478,-11.14716043,-9.72966774,-13.23164138,-9.125238434,-12.67453101,-7.123150443,-2.884932529 -3734,R220N,0.056449047,0.033723154,-0.008871641,-1.654448986,-2.334290873,-0.046587683,0.077944683,0.03495341,-0.064545366,0.001617618,0.06582869,-0.105505065,0.087761784,-1.789633115,-1.519264857,-2.422015664,-2.246566082,0.936321769,0.693529012,-12.06991081,-11.63068803,-11.71998899,-12.70133691,-11.54882051,-12.74871962,-7.682893109,-4.685203522 -3735,R220Q,-0.010781483,-0.002928433,-0.024666001,-0.837219853,-1.836778509,-0.069753118,-0.037920923,0.016357958,-0.081084822,-0.007694021,0.001837155,-0.066849361,0.017517359,-0.562185964,-1.112253741,-1.860015484,-1.813541534,1.817513216,1.45516832,-8.863474127,-8.119632751,-8.528393433,-9.98339225,-8.548515045,-9.137437157,-5.736047791,-3.556233426 -3736,R220P,-0.00830408,0.054148336,-0.612347998,-1.841706928,-2.097570762,-0.055375802,-0.008306196,-0.008301964,-0.044711684,0.029807155,0.078489517,-0.532583583,-0.692112413,-1.775557694,-1.907856162,-2.105316504,-2.089825019,3.231175122,2.046831322,-10.40492365,-11.47006301,-7.419134483,-10.62681299,-10.66990399,-11.83870377,-5.365955402,-0.753065333 -3737,R220S,-0.044056316,0.04914365,0.043992352,-1.273530005,-1.917546496,-0.009241303,-0.036562852,-0.051549779,-0.034710707,-0.003302386,0.101589685,0.006487453,0.08149725,-1.074905394,-1.472154615,-2.18319098,-1.651902012,2.124196556,1.424208441,-10.8510185,-11.23494728,-9.291543007,-11.6561132,-10.01143958,-12.06104945,-6.705582533,-2.754874814 -3738,R220T,-0.050152242,0.046440325,0.049117285,-1.56531545,-2.091349899,0.046932,0.001697222,-0.102001706,-0.044136774,0.028957266,0.063923383,0.026035173,0.072199396,-1.430936365,-1.699694534,-2.243044458,-1.939655339,0.635994059,0.706771914,-11.29876296,-11.29609029,-8.808989853,-12.74138766,-10.40615898,-13.24118801,-7.220746742,-3.057509802 -3739,R220W,-0.008660303,0.050848318,-0.309149768,-1.853507441,-2.373247326,0.087150357,-0.022652882,0.005332277,-0.020885703,0.002402567,0.099294069,-0.361571476,-0.256728059,-1.833403684,-1.873611197,-2.52377818,-2.222716471,1.449975172,0.743278537,-12.76040882,-12.28045736,-12.01479764,-13.06960883,-12.61656267,-13.82061761,-8.273217281,-5.709740313 -3740,R220V,-0.053283579,0.041751306,0.023613831,-1.947158609,-2.383732783,-0.000405249,-0.021952131,-0.084615027,-0.033201837,0.014598845,0.068903766,-0.00326251,0.050490172,-1.679878253,-2.214438964,-2.107011314,-2.660454251,0.728793715,0.690073638,-11.14999872,-10.42345905,-9.321664803,-12.83871162,-9.814937241,-13.35122092,-7.104713595,-3.256328392 -3741,R220Y,-0.019912628,-0.007508083,-0.341932645,-1.75187665,-2.470586539,-0.014996641,-0.009677584,-0.030147671,-0.07621079,0.005078817,-0.020094982,-0.371883692,-0.311981598,-1.896194514,-1.607558785,-2.285539014,-2.655634063,1.526687191,0.748963727,-14.14413983,-14.70015871,-13.54613392,-13.31502305,-13.63152787,-15.5278556,-9.262768053,-6.670061201 -3742,S221A,0.013296002,0.021205007,0.012065204,0.050383564,0.015870592,-0.076944536,-0.038312908,0.064904911,0.007767371,0.021880873,0.02052914,0.008652273,0.015478135,0.100515306,0.000251822,0.025711667,0.006029516,1.671448915,3.643209181,-1.347885735,-0.768136765,-1.635177101,-0.398970566,-1.405003159,-2.532141083,-2.723929683,1.535477682 -3743,S221C,0.018872096,0.044367091,-0.060994547,-0.011062432,-0.009742219,-0.036717413,-0.010593239,0.04833743,-0.031797666,-0.024359346,0.113093527,-0.129301454,0.00731236,0.016745958,-0.038870822,-0.086562894,0.067078456,1.329819675,2.332032883,-8.475028043,-7.970243286,-9.844140617,-7.725577065,-9.467887215,-7.36729203,-7.120383011,-4.502800562 -3744,S221E,-0.084293674,-0.01159765,-0.008828179,-0.004017073,-0.210797204,-0.08826096,-0.0873062,-0.081281147,0.000692625,-0.035253112,0.012057812,-0.024128174,0.006471817,0.059884003,-0.067918149,-0.191099347,-0.23049506,1.622205036,2.370122064,-6.127338478,-5.949451447,-4.732214211,-5.735446877,-6.772034813,-7.447545044,-5.966824107,-2.183214745 -3745,S221D,0.057000389,-0.052076572,0.026889536,0.085300181,-0.568615666,-0.088083853,0.020151066,0.093849712,0.130017655,0.046892478,-0.151045622,0.02258654,0.031192532,0.061664967,0.108935394,-0.376524014,-0.760707318,0.741994793,1.506499263,-8.225328279,-7.66687574,-8.49714093,-8.146097664,-8.555783196,-8.260743866,-5.254208108,-2.523986524 -3746,S221G,0.014584464,0.038798128,0.002388362,0.016935826,-0.267536734,-0.111027212,-0.002535934,0.031704862,0.017457676,-0.018081287,0.095677543,-0.0271893,0.031966024,0.02879191,0.005079741,-0.276685301,-0.258388166,1.143761305,1.803730218,-4.776545912,-5.210262978,-4.436986923,-4.250761993,-4.350130356,-5.634587311,-5.082922133,-0.133718807 -3747,S221F,-0.070243544,0.014366965,0.003140533,-0.053616917,-0.342966042,0.001359549,-0.052403838,-0.08808325,0.058813042,-0.118273065,0.147006994,-0.091397097,0.097678162,0.010529148,-0.117762982,-0.475764663,-0.210167421,0.835290152,1.492228805,-9.804486476,-10.00811293,-13.14730289,-7.119191322,-11.1129268,-7.634898438,-6.366700502,-2.11258775 -3748,S221I,-0.109875027,0.091608438,0.002263416,-0.023271166,-0.13567684,-0.112812016,-0.127954755,-0.091795298,0.033566993,0.034368902,0.148847973,0.058219267,-0.053692436,0.051290591,-0.097832922,-0.104565051,-0.166788629,1.219628573,2.220030138,-9.98848934,-9.573205688,-13.60964023,-8.773670403,-9.496280167,-8.489650215,-7.761173328,-5.00919614 -3749,S221H,-0.04351564,-0.01818806,-0.070630896,-0.047033608,-0.000773092,-0.05471765,-0.071646828,-0.015384451,0.027273431,-0.037840857,0.001464738,-0.073761118,-0.067500674,-0.007665661,-0.086401554,-0.077795603,0.076249419,1.37329066,2.431486283,-10.06415362,-9.153805969,-12.57953767,-8.187497459,-11.50255592,-8.897371094,-6.855869359,-3.240008175 -3750,S221K,0.040610096,0.006747372,-0.076716811,-0.0350234,0.008597157,-0.11000638,0.079181246,0.002038945,-0.109005691,-0.125873709,0.139368452,-0.137313625,-0.016119996,-0.088287569,0.01824077,-0.061371349,0.078565662,1.50874589,2.512586613,-3.516416499,-2.834184685,-5.154495407,-2.593554893,-3.256820854,-3.743026657,-3.272027757,-0.97603211 -3751,S221M,0.031015436,0.047522507,0.084795015,0.060518127,-0.057603585,-0.190118953,0.028357162,0.033673709,0.04745154,-0.022007565,0.117052578,0.016096061,0.153493969,0.079094931,0.041941322,-0.154689657,0.039482488,1.385047423,2.23542946,-9.753989439,-9.062403824,-11.60557642,-8.741639473,-9.460783363,-9.899544113,-6.688578859,-4.211018905 -3752,S221L,-0.05096451,0.034886939,-0.042189721,-0.011901386,-0.169576546,-0.085490355,-0.052174101,-0.049754918,-0.020368204,-0.065489126,0.135263004,-0.073203319,-0.011176122,0.011908588,-0.03571136,-0.233138434,-0.106014657,1.29694063,1.978694169,-8.037123225,-7.937766609,-10.80533835,-7.408326302,-7.638717079,-6.395467789,-5.585983425,-2.018267308 -3753,S221N,-0.030863859,-0.041810838,-0.032799748,0.04894479,-0.058641551,-0.163050348,-0.050082992,-0.011644725,-0.063402836,-0.035640356,-0.04798132,-0.038220985,-0.02737851,0.042168038,0.055721542,-0.08682381,-0.030459292,1.137945152,2.259826258,-7.162242485,-7.158728569,-8.213240372,-6.522565483,-7.867121353,-6.049556648,-6.50421611,-3.397661859 -3754,S221Q,0.010764664,0.134913907,0.047908309,0.005510137,0.106899351,-0.086650383,0.023684468,-0.00215514,-0.004700571,-0.0371704,0.306998214,0.011794144,0.084022473,0.037135601,-0.026115328,0.002330907,0.211467795,1.187935445,2.713764534,-6.98031357,-7.105926674,-7.153206261,-5.635041885,-7.7253871,-7.282005928,-5.349842585,-1.717457855 -3755,S221P,-0.017998835,0.086741931,0.020574503,0.018894151,-0.663132229,-0.119810327,-0.035590001,-0.000407668,-0.009511952,-0.008074316,0.181558177,0.007962382,0.033186624,0.049044128,-0.011255826,-0.678037496,-0.648226962,0.613258414,1.381434036,-6.390957773,-5.563917061,-8.476049164,-4.840417931,-7.354306587,-5.720098122,-5.086052801,-1.533751946 -3756,S221R,-0.029035473,0.050084472,-0.019447645,0.020411612,0.03387427,-0.03652268,-0.03491845,-0.023152495,-0.015429868,-0.025740938,0.125909882,-0.021042041,-0.017853248,0.063618305,-0.022795082,-0.012518433,0.080266973,1.142929939,2.456704713,-7.29006297,-6.411211807,-10.06768165,-5.395402908,-8.38271785,-6.193300636,-4.77619101,-0.664618282 -3757,S221T,0.047617461,0.057470325,0.03653916,0.048196176,0.009267263,-0.074329206,0.02556399,0.069670932,0.023198196,0.015027918,0.099912732,-0.005586139,0.078664459,0.074278057,0.022114295,-0.006062896,0.024597421,1.152478977,2.655967199,-4.705452983,-4.372473824,-4.703663322,-3.789113907,-5.135373642,-5.526640221,-5.289556943,-2.457402045 -3758,S221W,-0.064746557,-0.040322853,-0.043348812,-0.013905715,-0.625610278,-0.111746914,-0.023374049,-0.106119065,-0.020368204,-0.050124606,-0.0305211,-0.035614267,-0.051083357,0.05508432,-0.082895749,-0.538153727,-0.713066829,0.72662896,1.434049291,-12.16132428,-10.86875905,-14.86228707,-10.90045983,-12.86628578,-11.30882967,-8.459873712,-5.998991485 -3759,S221V,-0.037365534,0.048904572,0.01075248,-0.011484772,-0.061467424,-0.090112603,-0.081244208,0.006513141,0.011171408,0.001800453,0.09600869,-0.017843484,0.039348443,0.053341284,-0.076310828,-0.067540105,-0.055394743,1.198817323,2.316014929,-6.8813692,-5.833985687,-10.52621802,-5.939984795,-5.238935944,-6.867721558,-4.452027842,-2.873215645 -3760,S221Y,0.028502234,0.054065074,-0.04306758,-0.00507039,-0.107990138,-0.160906523,0.033340549,0.023663918,-0.040761362,-0.053804132,0.16193428,-0.058701498,-0.027433662,-0.026053127,0.015912347,-0.145153073,-0.070827203,1.329929066,2.153736191,-10.08620422,-9.817915703,-13.79009279,-7.678928177,-11.34765538,-7.796429062,-6.178912442,-2.381206605 -3761,A222C,-0.016669517,-0.089653733,-0.015116536,-0.082582702,-0.139486071,-0.002048456,0.07240973,-0.105748764,0.016064838,-0.14186067,-0.037446795,-0.000965403,-0.029267669,-0.090823682,-0.074341721,-0.158143286,-0.120828856,1.387948273,2.166400299,-5.915068031,-5.051879463,-6.235419556,-6.550109734,-6.620855087,-5.117076317,-5.496373791,-4.130638746 -3762,A222E,0.077525192,-0.04733885,-0.018074015,-0.002904115,-0.025283249,-0.08411219,0.149571888,0.005478496,0.011570546,-0.004035767,-0.090641932,0.003874122,-0.040022152,-0.004964739,-0.000843491,-0.017972302,-0.032594196,1.317512686,2.731157623,-3.25373109,-2.708708519,-3.485268822,-2.957793861,-2.907361412,-4.209522835,-2.752842573,-1.424835613 -3763,A222D,0.009232568,-0.044418049,0.066220203,0.017654796,-1.188570578,-0.096227727,0.093450993,-0.074985857,0.021890037,0.012306697,-0.101142794,0.069006666,0.063433739,0.029075077,0.006234514,-1.02824821,-1.348892945,0.544952934,1.336580847,-4.546954218,-3.678366013,-4.278986176,-4.479449806,-4.51753157,-5.780437523,-3.898611523,-0.805515128 -3764,A222G,0.011585791,-0.017558137,0.006071433,-0.018605645,-0.205126728,-0.107007095,0.046599478,-0.023427896,0.030729267,-0.017904847,-0.017211426,0.03992867,-0.027785805,-0.034008354,-0.003202936,-0.196198871,-0.214054584,1.511576925,2.226633823,-3.824290279,-2.862698364,-4.676835037,-3.644441124,-3.653767235,-4.283709633,-2.751825426,1.988226609 -3765,A222F,0.128752507,-0.00666986,0.081682797,0.030495898,-0.604300296,-0.061213862,0.172690739,0.084814274,0.070406951,-0.143993677,0.130653957,-0.01864422,0.182009814,-0.004620198,0.065611993,-0.629344174,-0.579256417,0.839728922,1.44451655,-5.349680391,-5.967559227,-3.699526833,-6.050998459,-5.451745461,-5.578571976,-4.547390027,-1.614463997 -3766,A222I,0.009843044,-0.055860866,0.066835569,-0.052945731,-0.127924825,-0.222302012,-0.019505985,0.039192072,-0.011433131,-0.043916227,-0.067805504,0.113363132,0.020308006,-0.117324478,0.011433016,-0.102199902,-0.153649748,1.399632289,2.270579901,-1.159869939,-0.361999245,-1.323499146,-1.533815506,-1.462224159,-1.117811638,-3.866328422,-2.668206369 -3767,A222H,0.069385264,0.007654783,0.021255012,0.036850787,-0.080251335,-0.101127496,0.125623744,0.013146783,0.00622198,-0.039392347,0.054701913,-0.035733336,0.078243359,-0.056847338,0.130548912,-0.13557676,-0.024925909,1.416113825,2.236840716,-3.507843648,-1.380369675,-3.190487755,-5.13312175,-3.890944672,-3.944294388,-2.592144486,-1.697351478 -3768,A222K,0.235088397,0.072227016,0.089258401,0.058121448,0.135756478,-0.132984593,0.419950457,0.050226337,0.040576987,0.05394058,0.090513452,0.047231559,0.131285242,0.006749417,0.109493478,0.010036137,0.261476818,1.069398933,2.43860654,-4.448323361,-3.052305031,-3.759271591,-5.185012459,-4.094806648,-6.150221077,-3.594185929,-1.173238727 -3769,A222M,0.005085756,0.018102366,-0.085416383,-0.071236818,-0.314588866,-0.054420423,0.069435098,-0.059263587,-0.059173059,0.025288318,0.010916414,-0.02184936,-0.148983405,-0.093739966,-0.04873367,-0.080655932,-0.5485218,1.138072556,2.134023299,-5.735192502,-4.006751396,-3.905764908,-8.425750946,-5.467276306,-6.870418953,-4.601691763,-1.598152687 -3770,A222L,0.032905125,-0.011462805,0.041377807,0.004574363,-1.220598653,-0.127724715,0.064336742,0.001473508,0.037593154,0.00075709,-0.023682699,0.04558834,0.037167274,0.00041224,0.008736485,-1.141003267,-1.300194039,0.760138953,1.34874475,-3.492198415,-1.606112823,-1.567982651,-6.180989342,-4.578330528,-3.527576729,-3.71999773,0.216618074 -3771,A222N,-0.042167086,-0.04235562,-0.015291484,-0.004257116,-0.165455814,-0.063853172,0.047043826,-0.131377997,-0.162032404,-0.060016013,-0.024695227,-0.058572167,0.0279892,0.039798942,-0.048313173,-0.146827887,-0.18408374,1.33464925,2.175488138,-5.345698087,-4.446358299,-5.880059372,-6.279324989,-5.652697975,-4.470049797,-3.973779239,-1.709857225 -3772,A222Q,-0.071985992,0.052772104,-0.021736684,-0.081044915,-0.035363378,-0.142716184,-0.05416115,-0.089810833,-0.044780496,0.014253019,0.091291188,-0.018454944,-0.025018423,-0.053622743,-0.108467087,-0.141064386,0.07033763,1.214426495,2.065198127,-3.529834631,-2.68050824,-2.628748772,-4.151490685,-3.491928917,-4.696496544,-4.206015428,-0.462552009 -3773,A222P,0.019195523,-0.0191551,0.007502622,-0.007001334,-0.20669553,-0.085291619,0.050764192,-0.012373146,0.005303772,-0.01280776,-0.02550244,0.023083459,-0.008078216,-0.011911869,-0.002090799,-0.194006923,-0.219384136,1.543956029,2.264664722,-6.196590298,-5.672433441,-5.457395241,-5.807366928,-6.823813728,-7.221942154,-5.053539579,-1.711381013 -3774,A222S,0.018724452,-0.044909163,-0.00795535,-0.014477048,-0.084670226,-0.070895657,0.096907899,-0.059458996,0.043756915,-0.055259351,-0.034558975,-0.005554094,-0.010356606,-0.039837301,0.010883206,-0.106603945,-0.062736506,1.287981567,2.198020287,-0.734378046,-0.184530312,-1.564515717,-0.918955681,-0.287408966,-0.716479553,-1.386100088,-1.08074493 -3775,A222R,0.092091915,0.009459268,0.000608778,0.007722338,0.012398433,-0.100592322,0.098652693,0.085531137,0.01527745,-0.045907121,0.064825657,-0.045509694,0.046727249,-0.046906362,0.062351038,-0.046128088,0.070924953,1.303740555,2.449109932,-4.010011943,-2.33474852,-4.46643689,-4.661193237,-4.764201317,-3.823479752,-2.757308849,-1.17503294 -3776,A222T,0.003360006,0.01135333,-0.008364168,0.008498593,-0.052968743,-0.109575344,0.020858174,-0.014138163,-0.017187222,-0.020878871,0.043585531,0.001151956,-0.017880292,0.020173716,-0.003176531,-0.040979728,-0.064957758,1.233385864,2.446336745,-1.794014113,-1.932711037,-1.936862419,-1.786013451,-1.938558487,-1.375925171,-3.173408666,-2.51385407 -3777,A222W,-0.003783173,-0.031795399,0.01776065,-0.001784315,-1.279806225,-0.09870786,-0.011950693,0.004384348,0.056525603,-0.102879388,0.03928859,-0.014093895,0.049615195,-0.062331502,0.058762873,-1.270249661,-1.289362788,0.923678207,1.359756544,-8.583818443,-6.975166878,-8.538917351,-9.055075874,-8.232452126,-10.11747999,-5.913620087,-4.060091644 -3778,A222V,0.018111134,-0.008535192,-0.020136527,-0.057140678,-0.038754442,-0.083972576,0.040061649,-0.003839381,-0.019038025,0.018670547,-0.035740931,0.036948103,-0.077221157,-0.081226168,-0.033055187,0.025505051,-0.103013935,1.255597429,2.862599988,2.269701924,2.360969681,2.282687073,1.864906281,2.439451302,2.400495285,-0.069132053,-1.175615759 -3779,A222Y,0.162187481,-0.022068089,0.010535828,-0.013866402,-0.274795451,-0.176021625,0.218252273,0.106122688,0.024970864,-0.0901051,0.045968922,-0.055390508,0.076462164,-0.040181374,0.01244857,-0.416263424,-0.133327477,1.711983017,2.076329274,-4.919914835,-3.125078659,-2.946452011,-6.278086662,-5.564075462,-6.685881378,-4.163625201,-0.205488006 -3780,L223A,-0.01622418,0.01503737,0.000725871,0.020766215,-0.244925714,0.0186056,-0.047784641,0.015336282,0.011096528,0.00955909,0.02051565,0.003388053,-0.001936311,0.007964207,0.033568222,-0.253065375,-0.236786052,1.668595501,2.259885159,-7.905869034,-7.419652771,-7.473060516,-8.629637367,-7.566490822,-8.440503693,-4.398811554,-2.897793467 -3781,L223C,0.011245554,-0.024437724,-0.052557504,-0.025110556,-0.05901323,0.076046747,0.008189447,0.014301661,0.025155486,-0.113581676,0.064706228,-0.121881357,0.016766349,-0.130483171,0.08026206,-0.142579074,0.024552615,1.48279952,2.211063669,-10.74498275,-10.74852754,-10.70893054,-10.69626759,-10.45178165,-11.11940641,-8.669689527,-7.326379412 -3782,L223E,-0.09717524,-0.006813721,-0.89948057,-2.364250753,-2.501219207,0.025868121,-0.112528124,-0.081822356,-0.148741651,-0.089756993,0.076129552,-0.757536795,-1.041424345,-1.919320589,-2.809180916,-2.618152041,-2.384286373,2.063227267,0.894287613,-11.62764005,-10.51035503,-11.20667743,-12.37671854,-11.04185017,-13.00259906,-8.674282246,-7.326379412 -3783,L223D,0.021922375,-0.171917599,-1.346041808,-2.217656778,-2.442670862,0.000637861,0.008065714,0.035779035,-0.096910013,-0.075398843,-0.268436355,-1.306744479,-1.385339136,-2.2167163,-2.218597255,-2.614517756,-2.270823967,0.94060404,0.096316325,-12.059419,-11.00098691,-12.27431371,-12.92290222,-10.75431664,-13.3445755,-8.293958587,-6.935782681 -3784,L223G,-0.003895253,-0.002914425,0.02203797,-1.455733325,-2.276690172,0.073134148,-0.032843647,0.025053142,0.029963223,-0.052279198,0.046450349,0.02910497,0.01497097,-1.362397224,-1.549069425,-2.429205461,-2.124174882,0.622004561,0.709792114,-12.02632829,-11.49228792,-11.76791464,-13.01556802,-11.40158453,-12.45428636,-8.696329311,-7.96929821 -3785,L223F,-0.024977389,-0.002282364,-0.043612913,-0.358286469,-1.850101859,-0.15845328,-0.075456522,0.025501745,0.202104691,0.043582285,-0.048147012,-0.104324281,0.017098456,-0.248379308,-0.46819363,-2.044120773,-1.656082944,1.320758408,1.325351849,-4.869585222,-6.032909218,-6.314973579,-3.971645416,-4.072522347,-3.955875549,-5.004782496,-1.803275865 -3786,L223I,0.057002232,0.100785274,0.090042963,0.047262776,0.039474144,0.050420747,0.036854142,0.077150321,-0.079181246,0.040202545,0.161368002,0.082627676,0.097458249,-0.058634451,0.153160003,-0.008086394,0.087034681,1.306142674,2.548760533,-4.430108545,-4.33567762,-4.255954102,-5.657927521,-3.562025009,-4.338958473,-4.195036769,-1.921591912 -3787,L223H,-0.008521296,-0.026784217,-0.148113904,-1.701266117,-2.545721245,0.023673538,0.015602982,-0.032645574,-0.071315413,0.000986232,-0.054554666,-0.128015415,-0.168212392,-1.61042476,-1.792107474,-2.344018318,-2.747424172,1.002539858,0.718188173,-10.81228895,-10.78739301,-10.48500703,-11.43800291,-9.549676071,-11.80136574,-7.896500984,-6.176094325 -3788,L223K,-0.047470387,0.099646223,0.0393871,-0.013767563,-1.688448663,-0.045375349,0.005877123,-0.100817897,0.057991947,0.101311422,0.097981023,-0.012626478,0.091400678,-0.08748448,0.059949355,-1.641633136,-1.73526419,0.569519494,1.308740624,-11.77766974,-11.59719617,-11.98750078,-12.00763389,-10.37262052,-12.92339734,-8.037370424,-7.065231075 -3789,L223M,0.021106208,0.116163703,0.122654043,-0.013270968,0.006047272,-0.106432169,0.014021532,0.028190884,-0.029963223,0.080504722,0.151822684,0.127824425,0.117483661,-0.020595408,-0.005946527,0.017331706,-0.005237163,1.006743881,2.549018873,-4.708148257,-5.997968605,-4.654316017,-3.843891151,-4.413504776,-4.631060738,-3.786231373,-2.83668985 -3790,L223N,0.022667769,-0.061991581,0.030404971,-1.431332535,-1.938482333,0.034348286,0.000300097,0.04503544,0.039152124,0.033203177,-0.157186338,0.022190843,0.038619099,-1.580502033,-1.282163036,-1.978303488,-1.898661178,0.976836863,0.709803886,-11.5227623,-11.12206615,-10.85744679,-12.19336495,-10.56183924,-12.87909437,-8.010345323,-6.255310565 -3791,L223Q,-0.0255447,0.067104691,0.029605576,-0.71343107,-1.936262751,0.154440689,0.070132223,-0.121221622,0.100115153,-0.0089338,0.143143182,-0.02077823,0.079989382,-0.266108075,-1.160754065,-2.182423471,-1.690102031,1.269096844,1.303578407,-10.27065863,-9.35040255,-9.963642426,-11.36048344,-8.922516006,-11.75624871,-7.442353359,-5.812606263 -3792,L223P,-0.015115276,0.013079278,-0.566095238,-1.829215168,-2.182385851,0.005690359,-0.037197308,0.006966756,0.019878148,-0.021559041,0.047717597,-0.451164165,-0.681026311,-1.880119687,-1.778310648,-2.446325573,-1.918446129,1.637591424,0.778482474,-11.71129259,-11.63045922,-11.37951077,-12.74659602,-10.96383489,-11.83606207,-9.03275832,-8.129810364 -3793,L223S,-0.03489905,-0.007726068,0.02858973,0.035860624,-1.648996795,0.037198629,-0.033105354,-0.036692745,0.042860252,-0.038710074,0.023257939,-0.010300126,0.067479585,0.032698836,0.039022412,-1.565418539,-1.732575051,0.594353921,1.312231164,-9.821718893,-9.656863091,-8.981269913,-10.79818472,-9.346191681,-10.32608507,-7.045515563,-5.676442226 -3794,L223R,0.003223101,-0.002708342,0.018615604,-0.118711418,-1.700886798,-0.010231094,-0.01815188,0.024598082,0.003088878,-0.02276727,0.017350587,-0.015271156,0.052502363,-0.064248087,-0.173174748,-1.899498092,-1.502275503,0.920572468,1.310891641,-10.64141882,-9.78075544,-10.12378861,-11.76364992,-9.337649635,-12.2012505,-7.744141444,-6.138711878 -3795,L223T,0.029845299,0.060832322,0.028537463,0.047910582,0.004756221,0.033113624,-0.002960111,0.062650708,-0.033471483,0.032979594,0.088685049,0.030050613,0.027024312,0.026472345,0.069348818,-0.040222143,0.049734584,1.462413316,2.745717539,-7.985387666,-8.331459152,-7.451654381,-8.406871681,-7.558410065,-8.178543053,-5.16574992,-3.914584847 -3796,L223W,-0.063666269,0.035789054,-0.053210089,-1.911610452,-2.592646951,0.059376444,-0.066226636,-0.061105901,0.012774288,0.037347805,0.034230302,-0.036220915,-0.070199263,-1.472162558,-2.351058346,-2.414032058,-2.771261843,0.762831839,0.712952836,-9.260689902,-9.210002907,-9.44861528,-9.289189056,-8.190283142,-10.16535912,-7.534111542,-5.249384518 -3797,L223V,0.008292021,0.043944047,0.098212225,0.064780038,0.023457895,0.02904686,-0.025547664,0.042131706,0.015794267,0.008706848,0.079181246,0.076890746,0.119533704,0.072191301,0.057368775,-0.020315368,0.067231158,1.198314174,2.605887215,-3.920050482,-4.06213221,-3.862030777,-4.690224831,-2.775757729,-4.210106865,-3.920741057,-1.195345552 -3798,L223Y,-0.008152962,0.039692703,-0.192914747,-1.901500717,-2.1265148,-0.008984502,-0.048289796,0.031983873,0.092470848,-0.060793297,0.140178703,-0.216474261,-0.169355232,-1.427476078,-2.375525355,-2.302398788,-1.950630812,2.305009211,1.378185901,-9.825856645,-10.82243559,-10.91263068,-9.708652855,-8.210140732,-9.475423363,-7.628486029,-5.773600201 -3799,P224A,-0.043017932,-0.001777951,-0.036393722,-0.142841371,-1.655145079,-0.026180387,-0.012111798,-0.073924066,-0.025847882,0.018405448,-0.021961349,-0.042945743,-0.029841701,-0.035188712,-0.250494029,-1.800008258,-1.5102819,0.76686957,1.309204888,-6.756226282,-6.725311134,-7.805786743,-5.776037682,-6.467128502,-7.006867348,-6.647958967,-3.76872266 -3800,P224C,-0.011596534,0.027544647,0.038411022,-0.877989471,-2.236007119,-0.02648039,0.005647118,-0.028840186,-0.035634707,-0.004454533,0.059543827,0.094963241,-0.018141198,-0.377564445,-1.378414497,-1.962130348,-2.50988389,1.460913057,1.353243587,-10.43475911,-9.647742104,-11.74862837,-9.393007278,-9.591370384,-11.79304742,-9.077983614,-7.186463626 -3801,P224E,-0.035172761,0.046367644,-0.000937916,-0.029731004,-1.914921366,-0.030517181,-0.059532836,-0.010812686,-0.072918568,0.005321822,0.087413466,-0.07586155,0.073985719,-0.03983953,-0.019622478,-1.664510421,-2.165332311,0.572917774,1.307302544,-7.576746555,-7.556325745,-8.100586853,-6.54115641,-6.934353729,-8.751310036,-6.420307828,-3.977584671 -3802,P224D,-0.033585864,-0.026019976,-0.014224496,0.005120009,-2.002474635,-0.000570368,-0.037950318,-0.029221409,0.034125862,-0.02648143,-0.025558521,-0.02508796,-0.003361032,-0.037677512,0.047917529,-1.636966672,-2.367982598,0.790422107,1.317627204,-7.140060559,-7.323532669,-8.346831421,-6.161024925,-5.875889992,-7.993023788,-6.013145999,-3.595875109 -3803,P224G,-0.012840932,0.056897012,0.011608398,-0.01224639,-1.271180378,0.041937008,0.010892192,-0.036574055,-0.017412843,0.012490652,0.101303372,-0.004107239,0.027324035,0.01273982,-0.037232599,-1.171968673,-1.370392083,0.650722525,1.336324529,-7.536133981,-6.84745649,-8.935062103,-6.840902092,-6.608627396,-8.448621826,-6.624518818,-2.992341218 -3804,P224F,0.013097485,-0.003630826,-0.093967504,-1.969081501,-2.3177489,-0.081460861,0.027289499,-0.001094529,-0.007266823,-0.069147843,0.061886191,-0.164749954,-0.023185053,-1.815828763,-2.122334239,-2.335936676,-2.299561123,1.130635711,0.70552332,-12.10072019,-10.91148515,-13.62875553,-10.72770535,-10.48105875,-14.75459618,-10.51650051,-10.2897608 -3805,P224I,-0.102038463,-0.019671977,-0.133385399,-1.885639873,-2.345231646,-0.003216405,-0.100328279,-0.103748646,-0.198362004,-0.022680141,-0.016663813,-0.155630574,-0.111140224,-1.40689337,-2.364386375,-2.449880029,-2.240583263,1.036205686,0.747084567,-11.18310001,-9.606468536,-12.60415779,-9.130787895,-10.73356805,-13.84051776,-8.995547511,-6.918983342 -3806,P224H,-0.079697336,-0.012347119,0.017517412,-0.042706376,-1.47636862,0.007711568,-0.089324902,-0.070069769,-0.014445408,0.02912063,-0.053814867,0.01734668,0.017688144,0.035114513,-0.120527264,-1.552715024,-1.400022215,0.384268978,1.304825418,-8.705838693,-7.775807442,-10.26796344,-7.465959152,-7.150994904,-10.86846853,-7.567734486,-5.410661625 -3807,P224K,-0.069300817,0.161145901,0.074943041,-0.030139985,-0.676098286,0.068714059,-0.10624941,-0.032352223,0.248796027,0.012081965,0.310209836,0.064522814,0.085363267,-0.136602817,0.076322848,-0.909967944,-0.442228627,1.432759724,1.592215847,-8.160721033,-7.514103317,-9.183115562,-7.109516212,-6.867062675,-10.1298074,-7.33171222,-5.096049949 -3808,P224M,0.035407308,0.021170956,0.051235988,-1.051878651,-1.914560411,-0.175249005,0.037586829,0.033227786,-0.119180758,0.021665583,0.020676328,-0.040327927,0.142799903,-0.706129993,-1.397627308,-1.953236634,-1.875884188,1.920553719,1.45360928,-10.10780444,-9.107720955,-11.53885885,-8.871430885,-9.186659477,-11.83435202,-8.599491297,-6.442500222 -3809,P224L,-0.05968981,0.000158413,-0.033260264,-0.911043918,-1.96066277,-0.024097264,-0.049401175,-0.069978444,-0.031450363,-0.013925393,0.014242218,-0.044916192,-0.021604335,-0.437049656,-1.38503818,-1.814992431,-2.106333109,1.638867475,1.414121074,-8.515475665,-7.497302582,-10.21889217,-6.914930153,-7.30037307,-10.64588035,-7.089378791,-4.538880852 -3810,P224N,-0.056307478,0.138649963,-0.048755344,0.07126316,-1.789244767,-0.023253196,-0.081258822,-0.031356134,0.107466874,0.14833061,0.128969315,0.080046375,-0.177557063,0.157389673,-0.014863353,-1.721287558,-1.857201975,0.548063594,1.305195647,-8.203406854,-7.881507881,-9.584591934,-7.352781403,-6.692488724,-9.50566433,-7.319715298,-4.715187857 -3811,P224Q,-0.139773199,-0.002776924,-0.061100645,-0.023895899,-1.537817744,0.074839439,-0.104804169,-0.174742229,-0.052233969,-0.005292131,-0.000261716,-0.06535114,-0.05685015,0.119697163,-0.167488961,-1.445081146,-1.630554342,0.590954057,1.317453745,-8.002327081,-7.353986671,-9.033731209,-6.938495041,-7.300184135,-9.38523835,-7.513994098,-4.853308932 -3812,P224S,-0.008349018,0.024780353,0.015201058,0.005914849,-1.439181992,-0.012389199,-0.009926373,-0.006771662,-0.011102828,0.030487624,0.019073081,-0.016481808,0.046883924,0.024361943,-0.012532245,-1.384277238,-1.494086746,0.777484213,1.334834136,-6.353520973,-5.875726967,-7.35468499,-6.175396217,-5.657625999,-6.704170692,-5.83230788,-3.51359045 -3813,P224R,-0.02755549,0.035047398,-0.012817569,-0.024783169,-1.512772675,0.028531858,-0.012363096,-0.042747883,0.031283659,-0.000654856,0.070749651,-0.062249381,0.036614243,-0.008291128,-0.041275209,-1.538553041,-1.486992308,0.670212756,1.318099578,-7.909425864,-7.068386932,-9.649589073,-6.466253876,-7.317275787,-9.04562365,-6.256958472,-4.2432981 -3814,P224T,-0.025098663,-0.009297145,-0.015234195,-0.019709311,-1.37993249,0.001154306,-0.031481579,-0.018715746,-0.050878915,-0.05394096,0.035346671,-0.013345107,-0.017123283,0.014791454,-0.054210075,-1.526045945,-1.233819035,0.657655602,1.31723811,-7.954760509,-7.21993235,-9.120237213,-7.127081612,-7.687378189,-8.61917318,-7.496268219,-4.503390371 -3815,P224W,0.155323738,0.104441202,-0.314811937,-1.189150345,-1.887302746,-0.135060882,0.22880711,0.081840366,-0.028752873,-0.18138339,0.390265794,-0.447496882,-0.182126991,-1.754277005,-0.624023685,-2.399323655,-1.375281837,1.735409644,0.838257621,-10.71430771,-9.152137413,-12.33322221,-9.429019844,-9.661503189,-12.99565588,-9.116961557,-6.903278074 -3816,P224V,-0.038828877,-0.007651876,-0.029235934,-1.322304502,-2.505475291,0.027574585,-0.019703729,-0.057954025,-0.009280475,-0.050293669,0.034989918,-0.029579841,-0.028892027,-1.039446535,-1.605162468,-2.22856123,-2.782389352,0.813407844,0.760147532,-9.825943521,-8.655365234,-11.46084232,-7.761640915,-9.751205711,-11.50066342,-8.178654647,-5.507813129 -3817,P224Y,-0.10605901,0.016535639,-0.013409187,-1.698729333,-2.260381099,-0.001388359,-0.099498752,-0.112619267,0.068059863,-0.05165239,0.084723668,-0.08731696,0.060498586,-0.955539224,-2.441919442,-2.202645866,-2.318116331,2.052593775,1.400483877,-10.73663522,-9.245885048,-12.36798798,-9.373981468,-9.165609955,-13.52971162,-9.093148246,-6.903278112 -3818,A225C,0.017269176,-0.026362138,0.002254677,0.011390376,-0.100035783,0.005161288,-0.046757596,0.081295948,0.111255729,-0.043864969,-0.008859306,-0.031088152,0.035597505,-0.003126642,0.025907393,-0.107525935,-0.092545631,1.41491968,2.307297164,-6.644376936,-6.578554741,-6.79270018,-6.443468483,-6.904498505,-6.502662773,-7.231797203,-6.501824432 -3819,A225E,-0.123036721,-0.105161037,-0.046598694,-0.019734284,-0.084060168,-0.012837237,-0.193889195,-0.052184246,0.087486057,-0.095622867,-0.114699207,-0.018654179,-0.074543209,0.07010363,-0.109572197,-0.052449372,-0.115670964,1.356603722,2.615959336,-0.948817023,-0.556728256,-0.19142511,-1.478096519,-1.952691025,-0.565144203,-1.099744142,-0.432427558 -3820,A225D,0.052145342,0.061116697,0.026594273,0.020426556,-0.024881322,0.014741518,0.036573576,0.067717107,0.05844381,0.036707661,0.085525732,0.031345174,0.021843372,0.030323987,0.010529124,-0.061205982,0.011443338,1.309040408,2.490008569,-1.660967979,-1.670252892,-0.868933975,-2.081638298,-2.592804848,-1.091209885,-2.382661916,-0.355163543 -3821,A225G,-0.021080224,-0.032623571,-0.013176322,-0.01588891,-0.082549558,0.007140723,-0.057071062,0.014910615,-0.007557273,-0.003507058,-0.061740084,-0.022179235,-0.004173409,-0.020063097,-0.011714723,-0.05297309,-0.112126025,1.375386059,2.490627003,-2.571513362,-3.165200684,-2.230569252,-2.291406479,-3.173623825,-1.996766571,-3.178321663,-1.986585295 -3822,A225F,0.012164017,-0.017228241,-0.067781864,-0.008420174,-0.164486588,-0.066225441,-0.046034298,0.070362332,-0.052393029,0.025349682,-0.059806163,-0.071132793,-0.064430935,-0.040317888,0.02347754,-0.115565111,-0.213408065,1.363340166,2.209659556,-6.077455563,-6.091024574,-5.93890033,-5.91553968,-6.929479507,-5.512333725,-5.29973337,-4.417117756 -3823,A225I,-0.008786755,-0.086589304,-0.01092792,0.06226434,-0.067274635,0.00110001,-0.113523468,0.095949959,-0.054486019,-0.051096029,-0.122082578,-0.023708143,0.001852303,-0.025101922,0.149630601,-0.12661232,-0.00793695,1.31588563,2.209328913,-4.685157143,-3.992354271,-4.53245137,-4.801997681,-5.232195267,-4.866787125,-4.746965367,-4.119208708 -3824,A225H,0.029723128,-0.075093041,0.016963599,0.001112569,-0.076997698,-0.001974937,-0.001110047,0.060556302,-0.00675396,-0.080573889,-0.069612193,0.004872611,0.029054586,-0.030572701,0.032797838,-0.041428285,-0.112567111,1.311469748,2.424453589,-4.211403418,-4.571279221,-4.181038971,-3.733018448,-5.071993492,-3.499686958,-4.047325298,-3.220453862 -3825,A225K,-0.148695717,-0.034365795,-0.094658811,-0.014837452,-0.037823988,0.082731238,-0.320280172,0.022888739,0.065313078,0.027824302,-0.096555891,0.062406115,-0.251723737,0.068021586,-0.097696489,0.13225969,-0.207907665,1.151940518,3.077378005,-0.782812352,-0.69283844,-0.283972809,-0.701086617,-1.604513832,-0.631650063,-1.990355566,-0.389093481 -3826,A225M,-0.057493755,-0.078365413,0.054043667,-0.023300991,-0.048778137,-0.049142832,-0.13633176,0.021344251,-0.079702807,0.076502205,-0.23323303,0.091594505,0.016492829,-0.068346612,0.02174463,0.048512426,-0.146068699,1.118077568,2.698263369,-4.993606757,-4.686563904,-4.779492859,-5.315409767,-5.4346502,-4.751917053,-5.232160787,-4.307322029 -3827,A225L,-0.021005656,-0.076143294,-0.019279668,-0.028526079,-0.130718286,-0.01122536,-0.091537523,0.049526212,-0.035036231,-0.051163106,-0.101123482,-0.046999113,0.008439778,-0.053972769,-0.003079388,-0.091974795,-0.169461776,1.405581878,2.302168178,-4.223655783,-3.826370979,-4.340815529,-4.518628075,-4.75940963,-3.673054703,-5.152114678,-3.055797478 -3828,A225N,0.032214445,-0.028770424,-0.019696102,0.076029205,-0.054190921,0.0382627,-0.011809746,0.076238636,0.054575956,-0.085459816,0.027918969,0.049258316,-0.088650519,0.05356567,0.098492739,-0.007299239,-0.101082602,1.272442012,2.737469258,-2.848377235,-3.177025925,-2.44598616,-2.549922005,-3.537361618,-2.531590469,-3.296433498,-2.506198964 -3829,A225Q,-0.014750981,-0.129096663,-0.064232349,-0.091742982,-0.146481261,-0.07110552,-0.045210942,0.01570898,-0.05786576,-0.145202953,-0.112990373,-0.038463676,-0.090001022,-0.028969218,-0.154516746,-0.061886991,-0.23107553,1.299251671,2.391722178,-1.887291469,-1.717340775,-1.574923637,-1.860447258,-2.831227745,-1.452517929,-2.060792222,-1.576322918 -3830,A225P,0.008288088,-0.062441776,0.013205903,0.009265303,-0.066311541,0.006686353,-0.037760043,0.054336218,0.015350299,0.000488233,-0.125371785,0.012330932,0.014080873,-0.003478912,0.022009517,-0.009212706,-0.123410375,1.223670094,2.457657378,-2.177931781,-1.757925888,-2.307343948,-2.69355027,-2.539570473,-1.591268326,-3.389874228,-0.418896018 -3831,A225S,-0.018873985,-0.010810676,0.032625365,-0.021249774,-0.070292569,-0.025566332,-0.079845248,0.042097278,0.052108367,0.023076122,-0.044697473,0.03927969,0.025971039,-0.004677532,-0.037822015,-0.02328008,-0.117305058,1.456724113,2.579772302,-1.377313597,-1.521993439,-1.282395828,-1.112515625,-1.594942757,-1.374720337,-2.691981173,-0.971199368 -3832,A225R,-0.040886044,-0.048941272,-0.022352569,-0.020345929,-0.074905372,0.00960336,-0.07475165,-0.007020437,-0.004754494,0.016092866,-0.113975409,-0.00977957,-0.034925568,-0.021663825,-0.019028032,-0.037499945,-0.112310798,1.232750588,2.504239626,-2.779126674,-3.120920845,-2.36272728,-2.980047569,-3.641244705,-1.79069297,-2.859089653,-1.548018353 -3833,A225T,-0.017775801,-0.12434318,-0.041495997,-0.044757271,-0.144877326,0.014014756,-0.047225048,0.011673447,0.027018551,-0.070970657,-0.177715703,-0.038408948,-0.044583045,-0.032585052,-0.056929489,-0.084233226,-0.205521425,1.347373481,2.283897307,-1.728778268,-1.656881676,-1.613850487,-1.749705231,-1.744847603,-1.878606346,-1.49824478,-1.674361189 -3834,A225W,-0.027560495,-0.017800176,-0.022851985,-0.022187828,-0.178694793,-0.004249681,-0.090666174,0.035545185,0.103176563,0.062847324,-0.098447676,0.053126828,-0.098830797,0.013340668,-0.057716324,-0.167092103,-0.190297482,1.411615446,2.216937685,-7.528216719,-7.486145813,-7.668625237,-7.35643013,-8.133568207,-6.996314209,-7.290576706,-6.501824432 -3835,A225V,-0.037921393,-0.103804194,-0.0066078,-0.003373511,-0.062278785,0.025120854,-0.036165072,-0.039677714,0.008304811,-0.009016842,-0.198591545,0.032793439,-0.046009038,0.0000125,-0.006759522,-0.014381926,-0.110175644,1.270031354,2.57458469,-3.24142946,-2.864922867,-3.127967552,-3.442018486,-3.786228226,-2.98601017,-4.076565566,-2.848261292 -3836,A225Y,-0.065546067,-0.051310631,0.057600605,0.004113691,-0.111895308,0.069445915,-0.141781051,0.010688917,0.13789556,0.025349682,-0.127970943,0.121557728,-0.006356518,-0.066054815,0.074282196,-0.027352428,-0.196438188,1.21964132,2.419470378,-5.048541177,-4.907087624,-4.985202652,-4.908190796,-6.047012924,-4.395211891,-5.191748705,-3.511729462 -3837,G226A,-0.02805829,-0.008594361,-0.042628081,-0.012893184,-0.474043585,0.017153184,-0.061509053,0.005392473,-0.000819797,-0.017220322,0.0000316,-0.047420372,-0.037835789,-0.017984188,-0.007802179,-0.375837326,-0.572249843,1.370338457,1.85427305,-4.512396277,-4.535204086,-4.306642883,-4.881706207,-4.999916077,-3.838512131,-4.623638332,-2.500406782 -3838,G226C,0.035869467,0.017077352,-0.044959525,0.015524891,-0.89099476,-0.001515506,0.054589501,0.017149433,-0.011385761,-0.024339687,0.05849439,-0.082956996,-0.006962053,-0.047871215,0.078920997,-0.710726511,-1.071263009,1.06899582,1.495804583,-7.252169215,-6.894107636,-7.483968071,-8.181685349,-7.275459587,-6.425625435,-7.821726066,-5.575020196 -3839,G226E,0.010656361,0.081637855,-0.005545491,0.031012842,-0.084602038,0.014853399,0.056605216,-0.035292495,0.054098898,0.049086527,0.114189183,-0.054625461,0.04353448,-0.011447423,0.073473106,-0.125306422,-0.043897654,1.310944878,2.168496629,-4.419818419,-3.53692765,-4.866738403,-5.543896584,-4.694132568,-3.457396889,-4.410608713,-1.792871943 -3840,G226D,-0.001510372,0.007327787,-0.000857558,0.03638795,0.012588812,-0.003148563,0.02769337,-0.030714113,0.016805444,0.01672662,-0.002071046,-0.014987226,0.013272111,0.008895711,0.063880188,-0.005611049,0.030788672,1.2976643,2.624384642,-2.316870998,-1.888723701,-2.40872509,-2.787717216,-2.342844711,-2.156344269,-2.49368057,-0.721205249 -3841,G226F,0.034473617,0.026400036,0.023914218,0.00819226,-1.399590085,-0.017545442,0.042021437,0.026925797,-0.067609455,0.02307128,0.029728792,0.039856255,0.00797218,0.045698359,-0.02931384,-1.530511788,-1.268668382,0.338832218,1.304335829,-8.006319984,-7.711168953,-7.644680107,-8.704994492,-9.071811653,-6.898944717,-6.592626961,-5.321523658 -3842,G226I,-0.048287648,-0.024780553,-0.445642384,-1.83792246,-2.322454727,0.01028465,-0.082603049,-0.013972247,-0.135725275,-0.060524573,0.010963468,-0.259115844,-0.632168924,-1.990930537,-1.684914382,-2.120968565,-2.523940888,1.82469744,0.814229192,-8.049840837,-7.522062531,-8.316318092,-8.482666344,-8.651759941,-7.276397278,-7.016258183,-5.423042743 -3843,G226H,-0.045574919,0.006194538,-0.056825182,-0.002253544,-0.082656357,-0.008806224,-0.042434184,-0.048715654,0.05835067,0.014920213,-0.002531138,-0.068281532,-0.045368832,-0.027263767,0.022756679,-0.064943743,-0.100368971,1.381689683,2.444282611,-5.211127379,-4.786181442,-4.965749077,-6.075291275,-6.290398407,-3.938016693,-4.555310961,-3.557677144 -3844,G226K,-0.048999946,-0.013593891,-0.053575552,-0.014748637,-0.013250524,-0.027783641,0.009669006,-0.107668898,-0.292269182,-0.039045781,0.011857999,-0.089060102,-0.018091002,-0.048995054,0.01949778,-0.136923147,0.110422099,1.508442457,2.246936704,-5.646548543,-4.679388321,-5.883714485,-6.885149879,-6.371074875,-4.413415154,-5.855281364,-2.863425052 -3845,G226M,-0.026654239,-0.014913383,-0.031927095,0.000981908,-1.588387768,-0.02007503,-0.031595765,-0.021712712,-0.09433259,-0.011836813,-0.017989953,-0.037746581,-0.026107609,-0.006273919,0.008237734,-1.138073793,-2.038701743,0.768026743,1.353773902,-9.601171872,-8.837311119,-9.347448425,-10.64593247,-10.1948135,-8.980353844,-9.027558469,-7.580752579 -3846,G226L,-0.024114795,0.024781845,-0.038626556,-0.101567131,-1.89747051,0.034083143,-0.028336232,-0.019893357,0.023011412,0.013687924,0.035875765,-0.07616727,-0.001085841,-0.048730841,-0.154403421,-1.807331552,-1.987609468,0.90461726,1.315417269,-7.574734381,-6.715706413,-7.389773369,-8.160457016,-8.588859001,-7.018876106,-6.485994681,-3.723148487 -3847,G226N,-0.054262096,-0.031425987,-0.033606435,0.019276097,-0.127757168,-0.055398386,-0.013601084,-0.094923107,-0.013304963,0.012271216,-0.07512319,-0.039864823,-0.027348047,0.028072395,0.010479799,-0.06811379,-0.187400546,1.325165349,2.451458733,-3.364239191,-3.001116287,-2.881685814,-4.7115084,-3.644910484,-2.581974968,-4.268713261,-2.008772011 -3848,G226Q,-0.007904064,0.003729653,-0.042252909,0.043681387,-0.174763128,-0.013634443,0.049093704,-0.064901831,0.034445239,0.012555161,-0.005095855,-0.063788099,-0.020717718,0.066289044,0.021073729,-0.156931125,-0.19259513,1.335292827,2.197548525,-5.72221434,-4.595090385,-5.733821892,-6.965627434,-6.712464638,-4.604067352,-5.35394025,-3.510136159 -3849,G226P,-0.009819404,-0.014950279,-0.054511883,-0.016321519,-1.503568439,0.027223159,-0.023441224,0.003802417,-0.015233022,-0.021562249,-0.008338308,-0.079119535,-0.029904231,-0.017912514,-0.014730523,-1.579287631,-1.427849246,0.752758189,1.320445414,-7.323920963,-7.639528946,-7.497563339,-7.601591553,-7.941372078,-5.939548897,-6.775898058,-4.017059638 -3850,G226S,-0.003502261,0.015074522,-0.038332658,-0.014338116,-0.060375297,0.009052911,-0.023576791,0.01657227,0.030249729,0.025001329,0.005147714,-0.039071832,-0.037593484,-0.021507017,-0.007169215,-0.05512159,-0.065629004,1.392357865,2.486617971,-3.297024084,-3.309308258,-3.275399559,-3.914904922,-3.035837326,-2.949670357,-4.184662327,-2.211067685 -3851,G226R,0.023698355,0.01679643,-0.014131283,-0.002841736,-0.160583026,-0.03691833,0.01552629,0.03187042,-0.05884279,-0.007989091,0.041581951,-0.056470299,0.028207734,-0.026471573,0.020788101,-0.188644649,-0.132521403,1.469607535,2.169485859,-5.516256796,-4.734888077,-5.770504234,-6.416279892,-6.222399574,-4.437212204,-5.466075295,-3.354608817 -3852,G226T,-0.002206326,0.003734652,-0.030094608,0.003821777,-0.033124862,-0.019254309,-0.023206923,0.018794272,-0.062733604,0.008935643,-0.001466339,-0.018085349,-0.042103866,-0.013279501,0.020923054,-0.043562056,-0.022687667,1.411803633,2.550622049,-3.472849811,-3.03690741,-3.773463074,-4.113892174,-3.395925255,-3.044061142,-4.665947301,-2.270424481 -3853,G226W,-0.028769767,0.067235348,-0.008073909,-0.080928001,-1.645095743,0.093826928,0.002583622,-0.060123156,-0.062176459,0.047387577,0.087083119,0.016501294,-0.032649111,-0.004133508,-0.157722493,-1.758281668,-1.531909817,0.618209857,1.305969224,-8.481391104,-7.580779137,-8.516111649,-9.605213219,-9.217799141,-7.487052376,-7.682862413,-5.829208481 -3854,G226V,-0.020969047,-0.010163548,-0.071702969,-1.435945729,-2.483838409,0.024021784,-0.008415799,-0.033522295,-0.015151344,-0.027966539,0.007639444,-0.145080286,0.001674349,-1.24033601,-1.631555448,-2.207646741,-2.760030076,2.324857677,1.480619974,-7.241664972,-6.770716202,-7.7699552,-7.547092834,-7.889609901,-6.230950722,-6.50040679,-4.624450349 -3855,G226Y,-0.041627339,0.07340824,-0.006023717,0.005454194,-1.292676546,0.035901733,0.027611065,-0.110865743,0.009028154,0.048667668,0.098148811,-0.051107792,0.039060358,0.072394721,-0.061486333,-1.161961508,-1.423391584,0.547229362,1.3284864,-7.321787129,-6.930771194,-7.39348912,-8.169059464,-8.195932953,-5.919682915,-6.696968619,-3.626706397 -3856,W227A,-0.047163358,-0.054309791,-0.528130314,-1.902446588,-2.410115861,0.002412776,-0.066254225,-0.02807249,-0.00578764,-0.09404905,-0.014570532,-0.42170382,-0.634556808,-2.051034164,-1.753859012,-2.659829754,-2.160401967,1.512285839,0.705513228,-8.749722006,-6.350812096,-11.92763999,-6.505862175,-8.602806091,-10.36148968,-5.185798733,-1.447156194 -3857,W227C,-0.040011906,-0.15387434,-1.444023789,-2.277929629,-2.601610509,0.028663968,-0.037310162,-0.042713649,0.038556913,-0.073734023,-0.234014657,-1.52344397,-1.364603607,-2.385730945,-2.170128312,-2.430255105,-2.772965912,0.69745505,0.032924532,-10.45614405,-8.840139519,-13.39540939,-8.21285157,-9.891450417,-11.94086938,-7.479619059,-5.837160653 -3858,W227E,-0.067131705,-1.326228142,-2.115266861,-2.633820115,-2.874335284,-0.000734089,-0.067666084,-0.066597325,0.040218174,-1.274348821,-1.378107463,-2.178138719,-2.052395003,-2.961244448,-2.306395781,-2.704738612,-3.043931955,0.133360591,-0.783099224,-12.66754355,-10.06290546,-16.13431291,-10.46113841,-12.61191255,-14.06744842,-8.729899453,-5.767169502 -3859,W227D,-0.052516708,-1.175514232,-2.696327174,-2.825804803,-2.779304338,0.004722863,-0.086430418,-0.018602998,0.064698208,-1.151132989,-1.199895474,-2.485047579,-2.907606769,-2.569183304,-3.082426301,-2.914737459,-2.643871216,0.129055662,-0.721305704,-11.16212465,-8.867377159,-13.51814839,-9.096855293,-11.32721093,-13.00103146,-7.680339245,-5.690961738 -3860,W227G,-0.084443113,-0.054982211,-1.465433181,-2.237326418,-2.958552135,0.001558477,-0.072234613,-0.096651612,-0.024340168,-0.019363104,-0.090601317,-1.38151678,-1.549349581,-2.144878451,-2.329774385,-2.717676388,-3.199427881,0.88235344,0.075050397,-11.76640475,-8.953498878,-14.83887833,-9.395959297,-11.54829469,-14.09539256,-8.130351703,-5.480871175 -3861,W227F,-0.003553414,0.036031292,-0.033449549,-0.048965038,-0.845939091,-0.019739182,0.038371537,-0.045478365,0.02302182,-0.001757668,0.073820252,-0.034831952,-0.032067146,-0.082675824,-0.015254252,-0.692388615,-0.999489567,1.211021003,1.559308147,-7.694531615,-5.918701134,-11.14873684,-6.565628654,-6.872157021,-7.967434425,-5.7505161,-3.763447941 -3862,W227I,-0.062659166,-0.256688769,-1.549722425,-2.609369057,-2.474822963,0.015451241,-0.016284485,-0.109033846,-0.063428035,-0.180457074,-0.332920464,-1.697302348,-1.402142502,-2.480408077,-2.738330036,-2.348840978,-2.600804947,0.999686454,0.013407163,-10.21222814,-8.726114578,-13.32373914,-9.132508682,-9.424162949,-10.45461537,-7.361797153,-1.989329832 -3863,W227H,-0.046370979,-0.026141255,-0.969336917,-2.262726132,-2.736922009,0.019503267,-0.057128241,-0.035613716,-0.057202917,-0.009049164,-0.043233345,-0.864979948,-1.073693886,-2.204388178,-2.321064085,-2.549942333,-2.923901685,1.881342386,0.696924244,-11.7201346,-9.438374062,-15.84491682,-9.273831696,-11.24592738,-12.79762305,-9.290488647,-6.802986395 -3864,W227K,-0.037043001,-1.471868894,-2.325454961,-2.255962585,-2.859977118,-0.007116854,-0.023414056,-0.050671946,-0.05430162,-1.55767317,-1.386064618,-2.268338469,-2.382571452,-2.352474194,-2.159450976,-2.999058345,-2.720895891,-0.005323496,-0.982508703,-12.10586356,-9.57906134,-15.05113855,-10.20826182,-12.51061022,-13.18024586,-8.25227111,-5.672781251 -3865,W227M,-0.026012373,0.016057956,-0.11031298,-1.76822655,-2.730242755,-0.034871807,-0.060019227,0.007994481,0.062069126,0.006674494,0.025441418,-0.159248914,-0.061377046,-1.541060993,-1.995392107,-2.699528505,-2.760957005,1.081009437,0.737911742,-11.07819212,-9.718278183,-14.46238187,-9.167197685,-10.37966915,-11.66343374,-7.053809461,-4.217516955 -3866,W227L,-0.037928803,-0.598327783,-2.070746639,-2.386417219,-3.214010768,0.030487862,-0.041082404,-0.034775201,-0.023291243,-0.588438196,-0.608217369,-2.216433922,-1.925059355,-2.476660906,-2.296173532,-3.123245056,-3.304776479,0.843835647,-0.397234795,-8.963415829,-7.222629944,-11.71113733,-7.702530777,-8.295966629,-9.884814468,-6.149481142,-2.836913527 -3867,W227N,0.015379357,-1.227838038,-2.627131956,-2.606094587,-2.471548493,0.00521904,-0.01679854,0.047557254,0.014100014,-1.019520002,-1.436156073,-2.462579061,-2.791684851,-2.546714786,-2.665474387,-2.415147687,-2.527949298,0.459489664,-0.64814349,-13.08268429,-10.35125268,-15.57599986,-10.69797279,-13.31829711,-15.46989901,-9.854672592,-7.321889477 -3868,W227Q,-0.035924184,-1.027905073,-2.084500393,-2.184982048,-2.740541574,-0.001838448,-0.065097527,-0.006750841,0.066486328,-1.102765691,-0.953044455,-2.193642232,-1.975358553,-2.15283922,-2.217124875,-2.623332112,-2.857751036,0.15023451,-0.690536559,-12.87795307,-10.52295752,-15.66330035,-10.96900449,-13.52001027,-13.71449273,-9.279431646,-6.66516427 -3869,W227P,-0.047805659,-1.724440197,-2.167309203,-2.44252917,-3.576892624,-0.013242971,-0.060834267,-0.03477705,-0.131853494,-1.819835536,-1.629044857,-2.00762209,-2.326996315,-2.34703032,-2.53802802,-3.692584476,-3.461200771,-0.232599361,-1.11399797,-12.77688132,-10.23978833,-15.77915876,-10.63560801,-13.30776341,-13.92208809,-8.144402863,-4.822564772 -3870,W227S,-0.055388977,-0.042426411,-1.055911735,-2.285489605,-3.230124757,0.017154039,-0.058980786,-0.051797168,-0.014345718,-0.066262712,-0.01859011,-0.837305693,-1.274517776,-2.266324697,-2.304654513,-3.51496884,-2.945280674,1.739907943,0.596421914,-10.37615052,-8.173360168,-12.73343616,-7.546229561,-10.55875982,-12.86896691,-7.1572535,-3.092807579 -3871,W227R,-0.062827882,-1.457084516,-2.071461297,-2.585293772,-2.587686553,0.02215222,-0.053707065,-0.071948698,-0.004433616,-1.403714182,-1.51045485,-2.132604302,-2.010318291,-2.760808071,-2.409779472,-2.667029533,-2.508343572,0.157776742,-0.862477534,-11.21733548,-9.086990692,-13.78438659,-9.17543618,-11.57565248,-12.46421144,-8.321001857,-5.865106355 -3872,W227T,-0.057075614,-0.02174628,-1.133980669,-2.343091463,-2.947105996,0.076552392,-0.043108952,-0.071042276,0.064523816,-0.031754459,-0.011738101,-1.019316074,-1.248645264,-2.148774778,-2.537408148,-2.649230893,-3.244981099,2.033591494,0.751278268,-10.04969238,-7.627598534,-12.86571387,-7.803569435,-10.35474218,-11.59683789,-7.26029241,-1.298083407 -3873,W227V,-0.094859183,-0.105013368,-1.496315531,-2.249577294,-3.138425058,0.018926157,-0.101502615,-0.088215751,-0.038217254,-0.062679974,-0.147346762,-1.41489565,-1.577735412,-2.260792209,-2.238362378,-2.958528882,-3.318321233,0.880890257,0.072333904,-8.669829672,-7.087214264,-12.04006367,-7.335103584,-7.824304497,-9.062462349,-6.60490433,-0.823204093 -3874,W227Y,-0.120906119,-0.014422706,-0.032958013,-0.044935314,-2.100840027,-0.0000316,-0.150033655,-0.091778582,0.005579577,0.052028958,-0.080874369,0.011216606,-0.077132632,0.019530016,-0.109400643,-1.814831152,-2.386848902,0.743221252,1.305462926,-7.571193314,-5.681504318,-10.23329059,-6.674607315,-7.43728331,-7.829281036,-5.917534932,-3.075704734 -3875,F228A,0.034819101,0.104829803,0.038322882,-0.045568097,-0.705757337,-0.098981239,0.009592467,0.060045734,-0.040639287,0.061577249,0.148082356,0.009433944,0.067211819,-0.065061212,-0.026074982,-0.60266673,-0.808847944,1.045491769,1.513181738,-5.168662502,-5.113226021,-5.295019142,-5.796567574,-4.457975243,-5.180524529,-4.338709645,1.260315839 -3876,F228C,0.089684478,0.01809077,0.055160871,0.003833366,-1.422719484,-0.133256625,0.055160659,0.124208297,-0.075850467,0.030382629,0.005798911,0.001175358,0.109146384,-0.039480857,0.047147589,-1.43038452,-1.415054448,0.872519,1.339284859,-7.171091522,-7.324181786,-6.881897141,-6.62861274,-7.164868477,-7.855897469,-7.465080819,-3.121832967 -3877,F228E,0.007750809,-0.005245028,-0.000757452,-1.336517625,-2.649739417,-0.097190971,0.017515563,-0.002013945,-0.110446703,-0.000300862,-0.010189194,-0.017984364,0.016469461,-0.999541254,-1.673493996,-2.754895612,-2.544583222,0.783133907,0.76112441,-5.09736897,-4.414539215,-5.941707733,-6.213641182,-3.848675453,-5.068281265,-3.467671453,1.5606969 -3878,F228D,-0.024903281,0.062555582,-0.649745724,-2.314775154,-2.364827307,-0.099287651,-0.055121671,0.00531511,0.037109206,0.059384499,0.065726664,-0.415136341,-0.884355107,-2.152794341,-2.476755967,-2.226907461,-2.502747153,1.390829997,0.6532372,-6.149703581,-5.375492508,-6.971671127,-6.197008469,-5.752258682,-6.45208712,-4.353363582,0.185527642 -3879,F228G,0.063027426,0.068428654,0.061150803,-0.467575016,-2.117396431,-0.099691056,0.040606336,0.085448516,-0.071441785,0.054229776,0.082627532,0.030431014,0.091870592,-0.260459331,-0.6746907,-1.954708506,-2.280084355,1.270993628,1.333423407,-5.954611449,-6.549204926,-6.489244904,-4.585500549,-4.826127716,-7.322979149,-4.12292313,-0.118932827 -3880,F228I,-0.035738798,0.095551233,0.059271793,-0.10089648,-1.514573075,-0.033208732,-0.025844499,-0.045633097,-0.150017353,0.189553257,0.001549209,0.078866741,0.039676845,-0.01371353,-0.188079429,-0.834314893,-2.194831257,0.73612221,1.380227054,-3.871866818,-3.604431343,-4.094313042,-4.648792679,-3.370314613,-3.641482414,-3.908425378,1.516578741 -3881,F228H,0.054301557,0.059061415,0.027849324,-0.055433891,-0.929733827,-0.104414843,0.031796199,0.076806915,-0.074852487,0.089248,0.028874829,0.014855055,0.040843592,-0.087319198,-0.023548584,-0.688445443,-1.171022211,1.088151176,1.506760747,-3.869861568,-4.963229378,-3.592767998,-2.711591019,-3.68473658,-4.396982864,-4.654227133,-0.108022492 -3882,F228K,0.08967324,0.056720277,-0.063812484,-0.122202633,-1.376374769,-0.088401746,0.072002464,0.107344016,-0.172966551,0.075568303,0.037872251,-0.141492146,0.013867179,-0.072970171,-0.171435095,-0.925234542,-1.827514995,1.219185529,1.489159541,-4.066990816,-4.38103241,-4.525627075,-4.118061951,-4.174996559,-3.135236084,-3.242686282,2.137464243 -3883,F228M,0.005584345,0.044304052,0.015649041,-0.072049924,-0.167753136,-0.151367284,0.002006728,0.009161961,-0.118519518,0.047811779,0.040796324,0.021293647,0.010004434,-0.138107277,-0.00599257,-0.184574143,-0.150932129,1.331223188,2.041398221,-4.476601221,-4.976921379,-4.183011505,-4.049390121,-4.073266037,-5.100417061,-4.237412471,-0.834278134 -3884,F228L,0.016878473,0.067237508,0.044833205,-0.017086541,-1.38825315,-0.057057705,-0.014523362,0.048280308,-0.060330699,0.057245868,0.077229147,0.041523689,0.048142721,-0.070004229,0.035831148,-1.468747165,-1.307759135,0.98882085,1.348733371,-3.421797849,-3.911900291,-2.537674599,-3.327303879,-3.658739441,-3.673371033,-4.238509895,0.894428306 -3885,F228N,-0.098818831,0.1554642,0.082388889,-0.043138267,-2.058817623,-0.077984931,-0.153311456,-0.044326205,0.003440215,0.240461662,0.070466737,0.152238611,0.012539167,0.019575036,-0.10585157,-1.87408202,-2.243553226,0.620598587,1.300176463,-5.324353757,-5.43412072,-5.432065063,-4.536406723,-5.625005951,-5.594170326,-5.258665037,-0.081957632 -3886,F228Q,0.083771655,0.144144313,0.065153763,-0.069929773,-1.501144034,-0.083237594,0.066237532,0.101305778,-0.106043415,0.104261359,0.184027267,0.086501066,0.043806459,-0.041672925,-0.09818662,-1.585608061,-1.416680006,0.700612841,1.317037919,-4.183064699,-4.78273922,-4.395836441,-3.949981178,-3.77038089,-4.016385765,-3.029024364,1.50933927 -3887,F228P,0.013825108,-0.712075188,-2.204574912,-2.550107461,-2.929335691,-0.060439926,-0.001243225,0.02889344,-0.003682261,-0.626285973,-0.797864402,-2.410693656,-1.998456168,-2.495139142,-2.60507578,-2.775306745,-3.083364636,0.375239692,-0.528984935,-5.770727083,-7.182700287,-4.007586029,-6.380903625,-4.313259193,-6.969186279,-4.857002713,1.172139024 -3888,F228S,0.033219423,0.092614051,0.049866853,-0.034156986,-1.232204024,-0.090313242,0.035132136,0.03130671,-0.037012462,0.068632179,0.116595923,0.035631919,0.064101786,-0.071035672,0.002721701,-1.093353346,-1.371054701,1.008833687,1.39886342,-3.487704623,-3.673370949,-3.482045509,-2.858377022,-3.65195256,-3.772777077,-3.248539504,1.208492804 -3889,F228R,0.035772611,0.080506595,0.051593198,-0.023338256,-1.14201242,-0.070295346,0.031534207,0.040011015,-0.076658189,0.102148642,0.058864547,0.061632592,0.041553803,-0.051694437,0.005017925,-1.169159546,-1.114865294,0.864773419,1.359032023,-4.708698016,-5.316103622,-4.486409752,-4.138878761,-4.515474533,-5.086623413,-2.411800269,2.668677613 -3890,F228T,0.040537346,0.019403695,0.004287443,-0.080922555,-1.022036606,-0.103798664,0.021386807,0.059687885,-0.08235759,-0.033483714,0.072291103,0.00657039,0.002004495,-0.13765627,-0.024188839,-1.040710192,-1.00336302,1.138127468,1.435564908,-3.799296155,-3.161730927,-3.719481552,-4.184201584,-4.234009308,-3.697057404,-2.816548484,2.449725001 -3891,F228W,0.04264328,0.004783932,0.018125335,-0.04195293,-0.201357558,-0.078061522,0.028096978,0.057189581,-0.006295387,-0.020114455,0.029682318,0.003366641,0.032884028,-0.041478205,-0.042427654,-0.184507149,-0.218207967,1.583149769,2.310440244,-4.835200641,-5.161342194,-4.055635605,-4.667095711,-4.736917007,-5.555012688,-5.584854934,-1.092872427 -3892,F228V,-0.0015192,0.071191963,0.044245122,-0.056016408,-0.947842669,-0.092051485,-0.029686123,0.026647724,-0.075979632,0.095450265,0.04693366,0.048900725,0.039589519,-0.063328881,-0.048703934,-0.737333767,-1.158351571,0.936995616,1.442488393,-4.34699781,-4.07201783,-4.574214615,-4.729499374,-4.00350502,-4.355752213,-4.063435392,2.198252874 -3893,F228Y,0.083847173,0.059318418,-0.047205919,-0.054358355,0.082612214,-0.089084387,0.095368918,0.072325427,-0.076910254,-0.008512641,0.127149476,-0.041512901,-0.052898936,-0.087355014,-0.021361696,0.031694729,0.133529698,1.209169271,2.751116301,-0.957602621,-1.002206535,-0.913874146,-0.859307571,-0.961998466,-1.050626389,-2.555011872,-0.956348581 -3894,I229A,-0.069410175,-0.009194267,-0.022617725,-0.498010987,-2.164150476,-0.047322728,-0.058249232,-0.080571118,-0.025520719,0.044674723,-0.063063257,0.059230841,-0.10446629,-0.140983006,-0.855038968,-2.051746359,-2.276554592,0.986912628,1.302322145,-8.416061873,-6.684182381,-8.170437576,-8.217985657,-7.841819763,-11.16588399,-5.843884611,-1.729619459 -3895,I229C,-0.018434574,-0.038239933,-0.00527992,-0.03924641,-0.262866813,-0.021814132,0.005045292,-0.041914439,0.007929562,-0.022655198,-0.053824668,0.07778862,-0.088348459,-0.01172377,-0.066769049,-0.251743379,-0.273990247,1.203413474,1.873144023,-10.74783069,-9.858151581,-10.27910246,-11.79328159,-9.773461304,-12.03515653,-7.446944099,-3.797866888 -3896,I229E,-0.118163448,-0.204449049,-1.606157646,-2.408972436,-2.863877939,-0.000181306,-0.093616218,-0.142710677,0.010441283,0.000471372,-0.40936947,-1.545095894,-1.667219398,-2.470514563,-2.347430309,-2.609540769,-3.118215109,0.557465311,0.02243671,-12.00268332,-10.11901456,-12.04317039,-12.14820953,-10.24863245,-15.45438969,-8.45180826,-5.495237654 -3897,I229D,-0.036650925,-0.530136698,-1.819078912,-2.118193194,-2.890113296,-0.031067167,-0.013327668,-0.059974181,-0.012719905,-0.261476316,-0.79879708,-1.874656978,-1.763500845,-2.322954392,-1.913431996,-2.859920608,-2.920305984,1.082465498,-0.048597466,-14.4124682,-12.86251445,-14.51752683,-14.76061289,-12.63306866,-17.28861816,-10.72163131,-9.040801153 -3898,I229G,-0.084474875,-0.045300644,-1.45001766,-2.321530954,-2.758309934,-0.048092622,-0.063402845,-0.105546904,-0.04973572,0.01285798,-0.103459268,-1.38423598,-1.51579934,-2.272992663,-2.370069244,-2.768566193,-2.748053674,0.656482615,0.05557492,-12.37320936,-9.398242386,-12.37932755,-13.29583441,-11.61978018,-15.17286228,-7.923392099,-4.333446926 -3899,I229F,-0.112505894,-0.05666062,-0.030493907,-1.482905359,-2.078295963,-0.101889922,-0.099795331,-0.125216456,-0.042873301,0.046136574,-0.159457813,0.030374443,-0.091362257,-1.210714747,-1.755095971,-2.066439725,-2.090152201,2.340730752,1.551669064,-9.670601863,-8.691327583,-7.817211334,-11.37656223,-9.782511688,-10.68539648,-6.00651842,-1.495245675 -3900,I229H,-0.082700661,-0.032096909,-1.295386883,-2.106377184,-2.982101441,-0.011462224,-0.041880875,-0.123520447,-0.02844013,-0.011823811,-0.052370006,-1.258517678,-1.332256087,-2.116989557,-2.09576481,-2.954985768,-3.009217113,0.734773484,0.085176321,-14.97365578,-12.65760128,-14.02125831,-15.33147475,-14.20916115,-18.64878344,-9.505399031,-6.020180212 -3901,I229K,-0.059801699,-0.031431826,-1.498162846,-2.30070772,-3.030689638,-0.046516218,-0.022964226,-0.096639171,-0.086822119,0.000564448,-0.0634281,-1.33702612,-1.659299572,-2.341626035,-2.259789405,-2.924349741,-3.137029535,0.628572103,0.06431168,-14.24863385,-12.90801746,-13.65958093,-14.39900317,-12.33425845,-17.9423092,-10.72610791,-9.063402344 -3902,I229M,-0.034686191,-0.002498985,-0.006363678,-0.017867238,-0.607769943,-0.054066044,-0.005625576,-0.063746806,-0.049273679,0.045896428,-0.050894398,0.065103162,-0.077830517,0.032555315,-0.06828979,-0.46860607,-0.746933816,0.680750987,1.450953409,-7.612678645,-7.719456772,-7.133450409,-9.892551598,-7.925485435,-5.392449013,-6.642132025,-3.341766762 -3903,I229L,-0.072972947,-0.023108798,-0.031415698,-0.023144424,-1.216477581,-0.100695239,-0.064336139,-0.081609755,-0.049137369,0.026071916,-0.072289511,0.053992976,-0.116824371,0.058049131,-0.104337979,-1.140424698,-1.292530463,0.658855608,1.338664433,-6.81619496,-6.270641006,-5.879656075,-8.929904037,-6.016914757,-6.983858925,-5.272553434,-1.092207017 -3904,I229N,-0.083550736,-0.051992474,-0.81172786,-2.243190302,-2.685684014,-0.001593391,-0.057831311,-0.10927016,-0.004905019,-0.008567874,-0.095417073,-0.476507721,-1.146947998,-2.305016377,-2.181364227,-2.74507258,-2.626295447,1.362198087,0.565428192,-13.80432748,-12.07785767,-14.78292802,-14.09083838,-12.32167987,-15.74833346,-9.905708836,-6.682768411 -3905,I229Q,-0.059360261,0.006274115,-1.374345993,-2.319778647,-2.908487271,-0.013432571,-0.035474562,-0.08324596,-0.061296401,-0.001026605,0.013574835,-1.300765153,-1.447926833,-2.210389555,-2.429167739,-2.872294507,-2.944680034,0.637943334,0.069397219,-14.12067794,-12.755091,-14.0205646,-14.24484502,-11.79798397,-17.78490512,-10.72610791,-9.063402344 -3906,I229P,-0.08172216,-1.610386677,-2.262329793,-2.334286207,-2.979966506,-0.014989348,-0.070993975,-0.092450345,-0.106152031,-1.733628547,-1.487144806,-2.262266235,-2.26239335,-2.006794762,-2.661777651,-2.70346182,-3.256471191,-0.160249955,-1.110350261,-13.78547602,-12.33307677,-13.7965256,-14.21220858,-12.72580354,-15.85976559,-9.560169155,-6.410978878 -3907,I229S,-0.07371826,-0.036303463,-0.407388759,-2.036565943,-3.095345961,-0.014685356,-0.060980944,-0.086455576,-0.055108184,-0.003009297,-0.069597629,-0.256925732,-0.557851786,-1.926341375,-2.14679051,-2.915605261,-3.275086661,1.27897484,0.701574246,-10.05259946,-8.113501747,-11.09416805,-10.87198161,-9.026331032,-11.15701486,-6.461403316,-2.689590051 -3908,I229R,-0.088189977,-0.158592143,-1.681584515,-2.335897718,-2.89429032,-0.02983625,-0.06344221,-0.112937744,-0.043233282,-0.055508222,-0.261676063,-1.642970694,-1.720198335,-2.249261145,-2.422534291,-2.714871452,-3.073709188,0.721068674,0.006662591,-14.29713226,-12.98181963,-13.76461433,-14.29879346,-12.12302988,-18.31740396,-9.021325448,-5.802377582 -3909,I229T,-0.089289656,-0.021184647,-0.53331329,-1.948994764,-2.658762353,-0.015301062,-0.074858868,-0.103720444,-0.021092378,0.007532816,-0.049902109,-0.278871639,-0.787754941,-1.765362048,-2.132627479,-2.533722331,-2.783802375,1.324510706,0.736903672,-8.751654924,-7.389862885,-8.416578384,-9.533736725,-8.59171357,-9.826383057,-5.978377228,-1.92299447 -3910,I229W,-0.045147097,-0.025102576,-0.844125942,-2.034534118,-2.749148727,-0.011215716,-0.022435188,-0.067859006,-0.069621072,-0.044462812,-0.005742339,-0.672743717,-1.015508166,-2.218447198,-1.850621037,-2.433194118,-3.065103335,1.692505073,0.65505085,-12.86131018,-11.80160159,-11.50875249,-13.2472619,-11.82041119,-15.92852374,-7.877753956,-2.184050546 -3911,I229V,-0.057768862,-0.03558698,-0.021215455,-0.017933436,-0.30258486,-0.033463746,-0.043185639,-0.072352085,-0.071251684,-0.013481006,-0.057692954,0.078010554,-0.120441463,0.045654115,-0.081520987,-0.268185207,-0.336984512,0.840184521,1.627879045,-3.68025253,-3.483888275,-2.826857544,-3.30088932,-3.981686073,-4.807941437,-5.118575373,0.808256287 -3912,I229Y,-0.059964285,-0.022906887,-0.003197551,-1.574836975,-2.505668973,-0.075255208,-0.03383762,-0.08609095,-0.03263289,0.005723961,-0.051537735,0.077142134,-0.083537235,-1.416998338,-1.732675612,-2.462120042,-2.549217903,0.618889537,0.705014533,-12.20591889,-10.59103956,-10.34467379,-12.83830901,-11.87163364,-15.38393846,-8.466165645,-3.511969808 -3913,A230C,0.07310897,-0.004171958,0.048859207,0.001506142,-0.216393002,-0.053046782,0.009368173,0.136849767,-0.016132044,-0.017617666,0.009273751,0.020522519,0.077195894,-0.022928851,0.025941135,-0.227233328,-0.205552675,1.301847205,1.990501504,-11.00741226,-9.420176544,-11.3167013,-11.21582285,-11.23938133,-11.84497926,-8.591221914,-6.522559779 -3914,A230E,-0.01785081,-0.938637313,-1.863561788,-2.141555238,-2.644688341,-0.029437271,-0.011906507,-0.023795112,0.108199615,-0.857785676,-1.01948895,-2.069408178,-1.657715397,-2.026454942,-2.256655533,-2.651368968,-2.638007714,0.354799882,-0.59052157,-8.183276454,-7.187504478,-8.119523651,-8.266883575,-9.182777184,-8.159693382,-6.660476608,-4.655544631 -3915,A230D,-0.05843501,-1.641969546,-2.02874737,-2.273901433,-2.743561141,-0.06765581,-0.063766253,-0.053103766,-0.002865578,-1.956292058,-1.327647034,-2.15088122,-1.906613519,-2.232866721,-2.314936144,-3.033872006,-2.453250275,-0.68648166,-1.113512379,-10.55394955,-9.299721893,-10.46668332,-10.8273447,-11.70386594,-10.4721319,-8.086664255,-6.03153719 -3916,A230G,0.025998699,-0.006894561,0.036733964,0.022933474,-0.023878032,-0.045517713,0.019219032,0.032778366,0.015902555,-0.006291192,-0.007497929,0.029334516,0.044133412,-0.004519398,0.050386345,-0.036233859,-0.011522204,1.324008576,2.494239028,-3.022619725,-2.631046188,-3.52214994,-2.592684502,-2.354714676,-4.012503319,-3.184488344,-0.667350843 -3917,A230F,0.003044142,0.018138504,-0.795527911,-2.128195162,-2.480813267,-0.019336381,0.024659935,-0.018571652,0.042794766,0.015549365,0.020727643,-0.504429139,-1.086626683,-2.177479247,-2.078911076,-2.501363277,-2.460263257,1.507483761,0.650746343,-11.1263077,-7.920529327,-9.904449295,-11.0034528,-13.911523,-12.89158408,-6.455278791,-3.865555981 -3918,A230I,0.034863112,0.001676746,0.042113699,0.015709083,-1.518781792,0.019535587,0.039806098,0.029920126,0.005619141,-0.061852423,0.065205914,0.013005243,0.071222155,0.010451374,0.020966792,-1.531542836,-1.506020747,0.724865554,1.321320016,-8.037424866,-7.436695923,-6.533652779,-7.785264503,-8.762618881,-9.668892242,-6.253143255,-3.764437635 -3919,A230H,-0.034737835,-0.579205569,-1.960485701,-2.418624129,-2.800238208,0.021204162,-0.037756676,-0.031718993,0.039513781,-0.441062438,-0.7173487,-2.062859405,-1.858111996,-2.211791695,-2.625456563,-2.535675725,-3.064800691,1.10133539,-0.196933048,-11.88315462,-9.425069763,-11.60423812,-11.38770529,-13.46344165,-13.5353183,-7.730192914,-4.778796479 -3920,A230K,-0.18703937,-1.195776298,-2.140636528,-2.264271566,-2.432901279,0.009118119,-0.218794322,-0.155284417,0.078420479,-0.997536292,-1.394016304,-2.11640474,-2.164868316,-2.198390241,-2.330152891,-2.522274271,-2.343528287,0.298042207,-0.642985108,-11.46725961,-10.14585313,-10.9941729,-11.76708222,-12.43277838,-11.99641143,-8.348859653,-6.875547631 -3921,A230M,0.00987137,0.025264624,-0.0000367,-0.009490556,-1.560654907,-0.005346253,0.024464831,-0.004722092,0.036060763,-0.034914851,0.085444099,-0.089611564,0.089538198,-0.092415819,0.073434707,-1.378975526,-1.742334287,1.013851818,1.361419387,-9.670725401,-8.979123085,-8.973285011,-10.04643431,-10.92424394,-9.430540657,-7.50578437,-6.029131173 -3922,A230L,-0.004442268,0.009531953,0.029722899,-0.536704787,-1.893065637,-0.040667257,0.01469173,-0.023576265,0.003129215,-0.018531753,0.037595658,0.001339901,0.058105897,-0.269701836,-0.803707737,-2.02991305,-1.756218224,1.31395131,1.325776552,-8.28114856,-6.228448631,-6.863342979,-8.58206649,-10.39068058,-9.341204117,-6.093341642,-3.850641903 -3923,A230N,0.065169214,-0.592148453,-1.93541351,-2.290927194,-2.741692622,-0.008096096,0.055185824,0.075152603,0.049316756,-0.46623989,-0.718057016,-2.224310138,-1.646516881,-2.607325634,-1.974528754,-2.931209664,-2.55217558,0.501796989,-0.453749162,-11.45653818,-10.63149962,-11.08081659,-11.70185131,-11.68044138,-12.188082,-8.460426617,-6.642807821 -3924,A230Q,-0.023695522,-0.103500283,-1.657534767,-2.053203827,-2.610909165,-0.020708925,-0.051239246,0.003848203,0.052047864,-0.071348852,-0.135651713,-1.700050487,-1.615019047,-1.848982777,-2.257424877,-2.649988062,-2.571830268,0.746073182,-0.000102915,-11.1032055,-9.470077972,-11.70854729,-11.01872617,-11.6031524,-11.71552365,-8.305837084,-6.47434758 -3925,A230P,-0.014726798,-1.694627089,-2.121499039,-2.362795216,-3.336932346,-0.007311352,-0.013914923,-0.015538673,-0.079101488,-1.831998537,-1.55725564,-2.144227197,-2.09877088,-2.259636454,-2.465953978,-2.981460492,-3.692404199,-0.477596666,-1.128753168,-10.04794205,-9.392321304,-10.02189403,-10.35748496,-10.32660672,-10.14140324,-7.725578966,-5.688545746 -3926,A230S,-0.003023597,-0.016084652,0.00952864,0.001800725,-1.721756113,-0.00892382,-0.012363881,0.006316688,0.033354575,0.004730953,-0.036900257,-0.002006527,0.021063807,0.021827495,-0.018226046,-1.728636519,-1.714875706,0.713462158,1.310446077,-6.392997943,-6.387666542,-6.076708595,-7.00126725,-6.447538292,-6.051809036,-6.592293261,-2.46894393 -3927,A230R,-0.026987875,-0.102298681,-1.510833571,-2.145455837,-2.621282413,-0.035452864,-0.042461235,-0.011514514,0.010826753,-0.068573798,-0.136023563,-1.49444992,-1.527217222,-2.101480228,-2.189431446,-2.772151744,-2.470413081,0.791102439,0.04887163,-11.54919984,-9.209257164,-12.41247314,-11.36251881,-12.29312255,-12.46862756,-7.600294077,-5.6077036 -3928,A230T,-0.037679194,-0.020095778,-1.142326498,-2.040107479,-2.911652176,-0.021789299,-0.045193905,-0.030164482,0.001968283,-0.011047388,-0.029144168,-1.022832036,-1.261820959,-2.062756191,-2.017458766,-2.898523583,-2.924780769,2.096421761,0.813381625,-9.361114528,-8.350548759,-9.115197433,-10.38899005,-9.838944298,-9.111892097,-8.253697788,-6.430092654 -3929,A230W,0.087262094,0.044934558,-0.095200537,-1.65611943,-2.481381369,-0.061574624,0.048870066,0.125654122,0.017124752,-0.040404255,0.13027337,-0.125779621,-0.064621453,-1.557528166,-1.754710694,-2.240434139,-2.722328599,1.047581533,0.730179042,-12.60324454,-10.10696928,-12.48599938,-12.94141858,-13.58021128,-13.90162418,-7.428156804,-4.646134273 -3930,A230V,-0.075575096,-0.012857571,-0.005644093,-0.064019977,-1.723396046,-0.021461276,-0.068913097,-0.082237095,0.038540228,-0.007933062,-0.01778208,-0.015905851,0.004617665,0.035172998,-0.163212951,-1.782947499,-1.663844592,0.716159621,1.307532352,-7.217438428,-6.355203529,-5.98487616,-6.906607704,-8.383994987,-8.456509758,-6.179491963,-4.243961558 -3931,A230Y,0.014798192,0.016326604,-0.167497955,-2.33271403,-2.714328109,0.033072957,0.045934892,-0.016338509,0.096786944,0.031352845,0.001300362,-0.121556739,-0.21343917,-1.92781811,-2.73760995,-2.853762131,-2.574894086,0.868984809,0.669904737,-11.97813137,-8.509947296,-11.55051458,-11.53893936,-13.83476137,-14.45649422,-6.183387994,-2.796177016 -3932,D231A,0.02150478,-0.031308565,-0.018840684,0.025798237,-1.433155759,-0.130587506,0.013137976,0.029871583,-0.00188233,-0.003464338,-0.059152792,-0.008024237,-0.029657131,0.020495221,0.031101252,-1.583391389,-1.282920128,0.68585368,1.315859977,-12.52445417,-15.20094563,-10.58945024,-11.99042255,-12.43972858,-12.40172383,-7.876084272,-3.005386881 -3933,D231C,-0.023477007,-0.180688987,-0.039066814,-0.581795958,-1.725629241,-0.103300304,-0.023537288,-0.023416725,-0.01713389,-0.052729613,-0.308648361,-0.050909473,-0.027224154,-0.572806101,-0.590785814,-1.839661537,-1.611596944,1.837156474,1.464475986,-14.36774703,-17.41568373,-12.83874007,-14.67206741,-14.8724793,-12.03976466,-8.124826844,-4.704388938 -3934,D231E,-0.054703638,-0.007488065,-0.02368147,-0.982891044,-2.05105119,-0.066203257,-0.021451001,-0.087956274,0.033970382,0.067640839,-0.082616968,-0.001116839,-0.046246101,-0.737138582,-1.228643505,-1.64959004,-2.45251234,2.26292779,1.746297518,-7.211638068,-10.33676988,-6.194371689,-4.920760361,-7.796875237,-6.80941317,-6.012169144,-3.321775866 -3935,D231G,-0.031729407,-0.069632209,-0.030286199,-0.913280782,-1.758466787,-0.111285005,-0.016771211,-0.046687602,0.009171964,0.01083364,-0.150098057,0.011554551,-0.072126949,-0.794679073,-1.03188249,-1.917151068,-1.599782505,2.079027688,1.531350614,-11.21315101,-13.44046407,-9.715814697,-10.49424036,-10.50487752,-11.91035838,-6.930495713,-2.008089853 -3936,D231F,-0.092474959,-0.139342899,-0.076766997,-1.731017515,-2.555596064,-0.011034545,-0.083785061,-0.101164857,-0.040296723,-0.072148869,-0.206536929,-0.06765242,-0.085881573,-1.904344325,-1.557690704,-2.741075068,-2.370117059,0.878103201,0.676465318,-17.91769814,-20.85068404,-15.5089045,-16.67570716,-19.95324709,-16.59994793,-8.311524423,-4.616693367 -3937,D231I,-0.034437642,-0.064439119,-0.038726923,-1.137602003,-1.741440104,-0.068078932,-0.008821192,-0.060054092,-0.035785415,0.056551867,-0.185430104,0.027466894,-0.104920739,-1.028068251,-1.247135755,-1.961709008,-1.521171199,2.318185927,1.62336739,-17.41571857,-21.46389272,-15.42449728,-15.98286625,-17.68820477,-16.51913185,-10.91672545,-9.471823037 -3938,D231H,-0.01461284,-0.120434953,-0.053184487,-0.718097704,-2.069796252,-0.059624782,0.019788431,-0.049014111,0.005902956,0.009621297,-0.250491202,-0.018989685,-0.087379289,-0.641414404,-0.794781004,-2.038450391,-2.101142113,1.797962596,1.39336116,-10.408529,-13.89447209,-6.087576782,-10.72936848,-10.85985939,-10.47136825,-6.7938933,-0.09620016 -3939,D231K,-0.155447312,-0.129983221,-0.053511524,-1.040931808,-2.095655881,-0.060421091,-0.167893857,-0.143000766,-0.035368265,-0.03077692,-0.229189522,0.009376693,-0.116399741,-1.031702536,-1.05016108,-1.935380069,-2.255931692,2.304627579,1.61597149,-17.00357504,-19.94821085,-16.50480152,-16.06061276,-16.78737693,-15.71687314,-10.95133296,-9.66088339 -3940,D231M,0.096874917,-0.015080802,0.063871564,-1.109071338,-2.377438798,-0.172960556,0.129193136,0.064556697,-0.003244411,-0.010646899,-0.019514704,-0.002103125,0.129846253,-0.926068954,-1.292073721,-2.628101124,-2.126776471,0.713532692,0.758569166,-17.8868029,-21.40642545,-16.61448894,-16.68018628,-17.65567476,-17.07723906,-10.95133296,-9.66088339 -3941,D231L,-0.01955362,-0.067638102,-0.026758858,-1.186572977,-1.942197894,-0.071941439,-0.001533806,-0.037573434,0.035970128,0.027952442,-0.163228646,-0.009591146,-0.04392657,-0.995185702,-1.377960252,-2.022248144,-1.862147644,2.249805501,1.56493623,-16.71648513,-20.06024461,-16.06066321,-15.30705621,-16.96542526,-15.18903633,-9.074075826,-6.132198026 -3942,D231N,-0.094655512,-0.115059001,-0.079820668,-0.084419143,-2.118517766,-0.069757351,-0.04023423,-0.149076793,-0.067703729,-0.066450453,-0.163667549,-0.023749651,-0.135891685,-0.055851824,-0.112986461,-1.844521122,-2.39251441,0.843163244,1.310274663,-8.245499789,-10.20744124,-7.047991074,-7.886701118,-8.583340446,-7.50202507,-5.640531499,-1.592780632 -3943,D231Q,0.009296067,-0.006101881,0.054436138,0.04086683,-1.815948013,-0.11526935,-0.001602808,0.020194942,0.029981455,0.120006322,-0.132210083,0.112268314,-0.003396039,0.073931046,0.007802613,-1.673858614,-1.958037411,0.744617696,1.314767674,-13.81750317,-17.58630382,-11.99865932,-12.07512873,-14.5897247,-12.83769929,-8.08318493,-4.053220639 -3944,D231P,-0.025129627,-0.0581517,-0.022263089,-1.342951722,-2.134817462,-0.012285551,-0.008799594,-0.04145966,-0.024651687,0.034701799,-0.151005199,0.015245792,-0.059771969,-1.146608492,-1.539294951,-2.155274534,-2.11436039,2.212031006,1.46114532,-16.61670105,-19.86104309,-14.49206679,-15.70908118,-16.49327897,-16.52803523,-10.95133296,-9.66088339 -3945,D231S,-0.044879811,-0.066896289,0.001676225,-0.253190316,-1.52339746,-0.066766269,-0.03292163,-0.056837991,0.028071235,0.044880156,-0.178672733,0.040801012,-0.037448563,-0.136276768,-0.370103864,-1.744762557,-1.302032363,0.74019438,1.309956944,-11.09138589,-15.11667183,-9.022924629,-10.89742574,-10.26687474,-10.15303251,-6.231782626,-1.63233183 -3946,D231R,-0.029619827,-0.069495134,-0.037858883,-1.593219528,-2.435618255,-0.011435605,-0.024178134,-0.035061519,0.013025219,0.013028031,-0.152018299,-0.002427939,-0.073289827,-1.442011022,-1.744428033,-2.375651778,-2.495584732,0.800768446,0.717246037,-15.3165288,-20.26387109,-11.12590406,-15.06020176,-15.41047896,-14.72218814,-7.937800905,-4.652442662 -3947,D231T,-0.029162024,-0.057831648,-0.025067173,-0.905203042,-1.694874876,-0.100302408,-0.007965576,-0.050358472,-0.017628374,0.016527136,-0.132190432,0.008892259,-0.059026604,-0.691574679,-1.118831404,-1.783003084,-1.606746668,2.058013686,1.582319521,-12.88532298,-17.11983724,-11.07061105,-12.26683265,-12.17877994,-11.79055403,-7.530063402,-4.575727903 -3948,D231W,-0.01440188,-0.068342765,-0.079749356,-1.614615125,-2.688892499,-0.012127568,0.003968834,-0.032772594,-0.01696164,-0.027823519,-0.10886201,-0.132876326,-0.026622386,-1.693278613,-1.535951636,-2.751858106,-2.625926891,1.017703006,0.710404665,-17.37247532,-19.63995239,-14.73155366,-16.65793226,-18.80848065,-17.02445762,-9.997386382,-7.224716754 -3949,D231V,-0.021635991,-0.056438037,-0.029804099,-1.418040477,-2.121734009,-0.130585275,-0.006528023,-0.036743959,-0.027080272,0.03748749,-0.150363564,0.050674658,-0.110282856,-1.266689581,-1.569391373,-2.091185868,-2.15228215,0.504656605,0.708746405,-15.5415534,-19.60045148,-12.72671576,-14.39001877,-15.89206888,-15.09851211,-9.388199098,-6.464888676 -3950,D231Y,-0.035408644,-0.068099344,-0.044574368,-1.340158007,-2.29251386,-0.00430867,-0.026289987,-0.044527301,0.061274864,0.066921451,-0.203120139,0.000932814,-0.090081549,-1.183881637,-1.496434377,-2.212497907,-2.372529812,0.643764212,0.724426607,-19.4444423,-22.94796281,-16.73211481,-18.12389132,-20.66852049,-18.74972209,-10.53155042,-8.194205584 -3951,K232A,0.073543302,-0.766008147,-1.948488494,-2.042948722,-2.767989534,-0.081793325,0.085738415,0.061348188,0.091917356,-0.847752287,-0.684264006,-2.072887013,-1.824089974,-2.20120549,-1.884691954,-2.607547589,-2.928431478,0.375256096,-0.588503511,-7.690485501,-7.224586563,-8.135931503,-8.40393261,-7.467156044,-7.220820786,-6.774196565,-6.631834117 -3952,K232C,0.061430049,-0.771615624,-1.889817967,-2.322201298,-2.572818371,-0.075518355,0.112126741,0.010733356,0.11668339,-0.831700548,-0.7115307,-1.826168059,-1.953467875,-2.204364009,-2.440038587,-2.786797367,-2.358839375,2.006635364,0.189572367,-10.69976607,-10.35565501,-11.10945867,-11.43157479,-10.78219494,-9.819946938,-8.744974318,-11.25201849 -3953,K232E,0.063966276,-1.346031429,-2.109651813,-2.218126403,-2.341107223,-0.058302935,0.073244112,0.05468844,0.085068051,-1.26314201,-1.428920848,-1.96757491,-2.251728715,-2.220832124,-2.215420682,-2.326144227,-2.356070219,-0.256491539,-0.782703596,-10.28574978,-10.14712431,-10.51823478,-10.96302866,-10.18988445,-9.610476707,-8.744974318,-11.25201849 -3954,K232D,0.064933144,-1.603653766,-1.955319779,-2.563794369,-2.425335817,0.015109717,0.102177971,0.027688317,0.069234779,-1.62089963,-1.586407901,-2.27957504,-1.631064518,-2.356740994,-2.770847744,-2.638144356,-2.212527277,-0.602673123,-1.028445642,-10.73892904,-10.17700193,-11.29808409,-11.66785584,-10.70428182,-9.847421501,-8.744974318,-11.25201849 -3955,K232G,0.110905655,-1.235698896,-1.84441732,-2.238105482,-3.141039615,-0.083689184,0.11955945,0.102251859,0.058762953,-1.331118178,-1.140279614,-1.834891627,-1.853943012,-2.046756156,-2.429454808,-3.369552203,-2.912527026,3.212951997,1.01462394,-10.65375057,-10.34063372,-10.9588671,-11.40688422,-10.66332354,-9.899044281,-8.744974318,-11.25201849 -3956,K232F,0.090013204,-1.796738536,-2.17398081,-1.867803514,-2.317390591,-0.13214657,0.118315063,0.061711345,-0.125038044,-1.840972122,-1.752504949,-2.198617536,-2.149344084,-1.798662236,-1.936944792,-2.557186852,-2.077594329,-0.343888897,-1.1379357,-11.50452171,-11.24553249,-12.23486275,-12.15371226,-11.74861314,-10.13988791,-8.744974318,-11.25201849 -3957,K232I,0.077505328,-1.37310446,-1.923740477,-2.293654441,-2.305710886,0.000307249,0.11898668,0.036023975,0.142530047,-1.303615553,-1.442593367,-2.184139712,-1.663341242,-1.960275671,-2.62703321,-2.542709029,-2.068712742,-0.129507476,-0.796770082,-9.336810474,-9.552835533,-10.18445738,-9.892172112,-8.917527084,-8.137060257,-7.255308863,-7.194662168 -3958,K232H,0.029465005,-1.608602736,-2.025435634,-2.041564508,-2.819360412,-0.059017493,0.051965913,0.006964097,0.008744913,-2.002585557,-1.214619914,-2.059200976,-1.991670291,-2.13636693,-1.946762086,-3.019830284,-2.61889054,-0.409005344,-1.105501505,-10.00958271,-10.09406387,-10.34819521,-10.47480766,-9.492454239,-9.638392601,-8.744974318,-11.25201849 -3959,K232M,0.084475796,-1.725535054,-2.165246697,-2.597630029,-2.459171476,-0.09996729,0.123313354,0.045638238,0.001279864,-1.844517402,-1.606552706,-2.327101553,-2.003391841,-2.404267508,-2.790992549,-2.68567087,-2.232672081,-0.419713412,-1.091112429,-11.07135051,-10.91415833,-11.80742413,-11.86289611,-10.94793958,-9.824334389,-8.623810746,-10.34132175 -3960,K232L,0.006560852,-1.766377365,-2.153721333,-2.29908903,-3.171225127,-0.030077978,0.020051739,-0.006930036,-0.026144048,-2.090161363,-1.442593367,-1.865950172,-2.441492493,-2.244146122,-2.354031937,-3.370647524,-2.971802729,-0.543038417,-1.130320421,-9.43603049,-9.353606667,-10.31724256,-10.41808569,-9.01531192,-8.075905617,-7.365328747,-7.328917168 -3961,K232N,0.103629755,-0.925740171,-1.930618698,-2.300532661,-2.312589106,-0.050263826,0.135438758,0.071820752,0.181573083,-0.917641077,-0.933839264,-2.229529001,-1.631708394,-2.306694955,-2.294370366,-2.588098317,-2.037079894,0.180452946,-0.620471113,-9.993179579,-9.381142319,-10.76366141,-10.76217239,-9.870181351,-9.188740433,-7.860709651,-7.967380962 -3962,K232Q,0.107199433,-1.392054498,-2.051432487,-2.094740194,-2.583917894,-0.021317778,0.135332172,0.079066694,0.076115696,-1.548275708,-1.235833288,-1.993071297,-2.109793677,-2.070237252,-2.119243135,-2.828761869,-2.339073918,-0.539286087,-0.994435159,-8.053912241,-7.838320564,-8.612745178,-8.542232491,-7.587720337,-7.688542633,-7.489686091,-7.325799114 -3963,K232P,0.015493356,-1.742160506,-2.108614335,-2.512195488,-3.126311925,0.031407025,0.048416615,-0.017429904,-0.076854392,-1.989698644,-1.494622367,-2.193529193,-2.023699477,-2.646358762,-2.378032214,-2.830852111,-3.421771738,-0.31520725,-1.135472472,-10.84425167,-10.48879866,-11.26675576,-11.56188834,-10.87240014,-10.03141547,-8.744974318,-11.25201849 -3964,K232S,0.105428878,-0.989881046,-2.085286912,-2.144111735,-3.110410689,-0.042518389,0.137735641,0.073122114,0.068454789,-1.10474279,-0.875019301,-2.378842152,-1.791731671,-2.103825589,-2.18439788,-3.33947146,-2.881349918,0.16681422,-0.69607527,-10.31687665,-9.820918045,-10.54060307,-10.99701662,-10.32670755,-9.899137955,-8.744974318,-11.25201849 -3965,K232R,0.064445581,-0.06086756,0.022663237,-0.028213132,-1.610509632,0.026038111,0.094699232,0.034191929,0.063558453,-0.17713307,0.05539795,-0.057326338,0.102652811,-0.053825149,-0.002601115,-1.880947867,-1.340071396,0.871460878,1.31066779,-3.630975427,-3.535489922,-4.39150013,-3.695062836,-2.80584742,-3.72697683,-3.514368827,-2.949270166 -3966,K232T,0.083565921,-0.906068049,-2.053486039,-2.134110555,-2.748226992,-0.079748701,0.087045812,0.08008603,0.092925813,-1.039174172,-0.772961926,-2.252136791,-1.854835287,-2.02827275,-2.239948359,-2.735644845,-2.760809138,0.206745854,-0.663600732,-8.359550649,-7.844947609,-8.847665573,-8.970301376,-8.196747375,-7.938091309,-7.023709431,-7.448672964 -3967,K232W,0.001001222,-1.931671252,-2.3379095,-2.113660606,-2.753353303,-0.01043169,0.02321227,-0.021209827,-0.096601726,-1.960087328,-1.903255176,-1.773664697,-2.902154302,-2.093868701,-2.13345251,-2.977332054,-2.529374552,-0.46540647,-1.132042495,-11.09683582,-10.97409312,-11.65188921,-11.75323758,-11.15150097,-9.953458214,-8.744974318,-11.25201849 -3968,K232V,0.025038074,-0.979286566,-2.206013843,-2.770017892,-2.719604968,-0.106735144,0.054507088,-0.004430941,0.13573722,-1.067712206,-0.890860926,-2.688599055,-1.72342863,-2.288643755,-3.251392028,-2.746138376,-2.69307156,-0.029632412,-0.688625712,-10.67735144,-10.74047121,-11.3315107,-11.25839244,-10.41691615,-9.639466721,-8.328212313,-9.200912815 -3969,K232Y,0.011627972,-1.738357113,-1.87703876,-2.096437725,-2.409524166,-0.039099912,0.017553965,0.005701979,-0.082547673,-2.076831586,-1.399882639,-2.258385741,-1.495691779,-2.335551695,-1.857323755,-2.616955057,-2.202093274,-0.371691475,-1.135335068,-11.20323113,-10.99004288,-12.02360719,-11.6689734,-11.46183777,-9.871694405,-8.744974318,-11.25201849 -3970,S233A,-0.002913284,-0.008919141,-0.029015492,-0.041034287,-1.023786368,-0.123000677,-0.030137135,0.024310567,0.033343499,-0.016752082,-0.001086199,-0.045282018,-0.012748965,-0.05352988,-0.028538693,-0.870418499,-1.177154236,1.601914341,1.688680834,-4.777834354,-3.966458855,-5.275302666,-4.187797821,-5.126283005,-5.333329422,-5.380325939,-3.290478632 -3971,S233C,-0.056668423,0.005768198,-0.205672685,-1.798893223,-1.777677999,-0.120822248,-0.067321836,-0.04601501,0.042712274,-0.060262707,0.071799103,-0.082084666,-0.329260703,-1.862126635,-1.73565981,-2.280592964,-1.274763034,0.912067208,0.682757946,-7.697366183,-6.312558243,-8.52914019,-6.966422661,-9.029300621,-7.649409203,-5.625619136,-3.191939194 -3972,S233E,0.041641453,-0.581458427,-1.934678895,-2.589449291,-2.908854686,-0.142116999,0.041089017,0.042193889,0.020777969,-0.662083385,-0.500833469,-1.987569432,-1.881788358,-2.764150868,-2.414747713,-3.085707184,-2.732002187,1.473879818,-0.118732667,-9.259359869,-9.211722496,-8.115876289,-9.231649307,-9.159769089,-10.57778217,-6.526460002,-4.020571731 -3973,S233D,-0.021052591,-1.574251332,-2.224201709,-2.407968079,-2.815419103,-0.173279584,-0.023664668,-0.018440513,-0.07879575,-1.960169,-1.188333663,-2.088374488,-2.360028929,-2.643107176,-2.172828981,-2.964663491,-2.666174714,-0.257817479,-1.117005097,-11.1971903,-11.19294387,-11.96260175,-10.82149415,-10.03824068,-11.97067107,-7.8202582,-6.630980121 -3974,S233G,0.033394994,0.04291568,0.006717937,0.008200309,-0.302187877,-0.120330205,0.013693091,0.053096896,0.00267282,0.017095324,0.068736036,-0.016792962,0.030228835,-0.011554552,0.027955169,-0.255220885,-0.349154869,1.538484432,2.155613264,-5.956546628,-6.022981918,-5.446235878,-5.33016497,-6.335826157,-6.647524216,-4.655795161,-3.163854358 -3975,S233F,-0.090564168,-0.702566854,-2.0543634,-2.598209422,-2.679054189,-0.048705548,-0.102155796,-0.07897254,0.007204959,-0.637244109,-0.767889599,-2.087668892,-2.021057908,-2.165280325,-3.031138518,-2.787866636,-2.570241742,0.76645888,-0.450964895,-11.27114156,-10.5059341,-12.41811362,-9.126551445,-11.25568946,-13.04941917,-6.76022354,-4.174097506 -3976,S233I,-0.016276483,-0.927354794,-2.443502052,-2.326238426,-2.583174452,-0.10789686,-0.001957902,-0.030595064,0.074180831,-1.029704337,-0.825005251,-2.464334853,-2.42266925,-2.064825031,-2.58765182,-2.863502601,-2.302846302,0.256310146,-0.662951432,-9.288046442,-8.630319527,-9.82844252,-9.341320076,-8.70461039,-9.935539696,-5.913011766,-2.449569311 -3977,S233H,0.021699277,-0.188259168,-1.579530864,-2.022554204,-2.540929603,-0.157985318,0.039852796,0.003545758,-0.018153172,-0.189184776,-0.18733356,-1.998631502,-1.160430226,-1.900151676,-2.144956732,-2.698829246,-2.38302996,0.894721186,-0.112637335,-9.935730826,-9.637008224,-9.996872726,-7.34124543,-9.94106942,-12.76245833,-6.602254827,-4.5167972 -3978,S233K,-0.094792722,-0.65658223,-2.377518646,-2.076266627,-2.429145416,-0.036082733,-0.073034849,-0.116550594,0.101529427,-0.516037423,-0.797127037,-2.411398778,-2.343638513,-2.011888956,-2.140644298,-2.333445271,-2.524845561,0.282454551,-0.505821621,-11.02515488,-10.53993854,-11.8891048,-9.442303276,-10.47039078,-12.78403699,-8.461979646,-8.36621116 -3979,S233M,0.067567706,0.056163506,-1.515111712,-2.142525942,-2.495404731,-0.158393998,0.0511371,0.083998311,0.063620542,0.061657562,0.05066945,-1.654819633,-1.375403791,-2.510582316,-1.774469567,-2.531108636,-2.459700826,0.299211971,-0.009781066,-11.17005204,-10.68482142,-11.58850202,-10.8575474,-10.89691033,-11.82247903,-7.521678823,-5.925439926 -3980,S233L,-0.047554248,-0.017874927,-1.527855187,-2.212910268,-2.653834687,-0.07045769,-0.044620847,-0.050487648,-0.009286563,0.013255807,-0.049005661,-1.525889056,-1.529821317,-2.173375796,-2.252444739,-2.561878901,-2.745790472,0.57748207,0.025442364,-11.58674515,-11.10211312,-12.85292254,-11.170969,-11.90112625,-10.90659482,-7.735812159,-5.925439926 -3981,S233N,-0.058782783,-0.167112867,-1.700682974,-2.27947458,-2.837440603,-0.065443339,-0.040372319,-0.077193247,0.01072854,-0.075063585,-0.259162148,-1.971814683,-1.429551265,-2.651486107,-1.907463053,-2.973042423,-2.701838782,0.311639603,-0.152816962,-7.445867848,-8.252419197,-7.84375074,-6.691624702,-5.923015648,-8.518528954,-5.627639628,-2.227014411 -3982,S233Q,0.033588952,-0.023655387,-1.54862578,-2.465455085,-2.395784855,-0.136311246,0.032653695,0.034524208,-0.0462634,-0.04812417,0.000813397,-1.720397703,-1.376853857,-2.27513039,-2.655779779,-2.596686706,-2.194883003,0.513246757,-0.021692058,-9.231069858,-9.089938889,-8.897967278,-7.668412712,-9.585470917,-10.91355949,-5.975568381,-2.316464156 -3983,S233P,0.015138462,0.031077404,-0.020468163,-0.536883634,-1.862269337,-0.123847399,-0.031721521,0.061998445,-0.007706189,-0.02706043,0.089215237,-0.061832351,0.020896026,-0.306131817,-0.767635451,-1.847796221,-1.876742453,1.448092214,1.36903937,-5.499267377,-3.625944046,-5.251581093,-3.996168251,-7.095897743,-7.52674575,-3.976412237,-1.806196873 -3984,S233R,-0.048622835,-0.357468884,-1.905316494,-2.390112859,-3.079699599,-0.0146084,-0.045116212,-0.052129457,-0.003932202,-0.33301734,-0.381920427,-2.073675542,-1.736957446,-2.276225711,-2.504000007,-3.074903282,-3.084495916,0.961366806,-0.188923128,-8.691011115,-9.177626465,-7.987243546,-6.983063133,-9.194494896,-10.11262753,-6.473013474,-4.504735051 -3985,S233T,0.041391567,0.059768649,-0.016953332,0.008724631,-0.036772807,0.184641421,0.025467528,0.057315606,0.022945881,0.012518895,0.107018402,-0.049191958,0.015285295,-0.031135995,0.048585257,-0.043851792,-0.029693822,1.253544913,2.438382286,1.552480899,1.357504593,2.273680122,0.509489838,1.560493813,2.06123613,-0.399767727,2.050442278 -3986,S233W,-0.014515148,-0.024619921,-1.337217823,-2.283506596,-2.514866361,-0.062181935,-0.007492678,-0.021537617,0.025171943,-0.037336158,-0.011903684,-1.475969417,-1.198466228,-2.757700832,-1.809312359,-2.602135893,-2.427596829,0.641043873,0.038702641,-12.46210702,-11.66486829,-13.05842155,-10.87946792,-12.3629908,-14.34478655,-8.461979646,-8.36621116 -3987,S233V,-0.003185508,-0.028056888,-1.435155577,-2.025274202,-2.819103336,-0.118760761,-0.007836195,0.001465179,0.002142543,-0.018939485,-0.037174291,-1.535043044,-1.335268109,-2.059812508,-1.990735895,-3.381368824,-2.256837847,0.805654504,0.03887636,-8.449287708,-7.507466934,-9.504335724,-8.277966629,-7.610648277,-9.346020973,-5.818733606,-3.255229624 -3988,S233Y,-0.007312254,-0.051809435,-1.595145808,-2.096276732,-2.716712122,-0.058815155,0.009462032,-0.024086539,-0.074815302,0.021828524,-0.125447394,-1.994275453,-1.196016163,-2.071886885,-2.120666578,-2.870564456,-2.562859788,0.335098279,-0.132583482,-11.76270984,-11.20507112,-13.12136493,-9.102277687,-10.89546326,-14.48937221,-6.593961966,-3.195317833 -3989,G234A,0.02863772,-0.001013679,-0.014388006,0.010276011,-0.451187719,-0.082190466,-0.009846142,0.067121582,-0.033045633,0.018556872,-0.02058423,0.002520087,-0.031296098,0.027390464,-0.006838443,-0.393264644,-0.509110793,1.00888511,1.619179944,-6.306129655,-6.258641098,-6.444292648,-6.241172073,-6.455270515,-6.131271942,-6.729732471,-5.946089075 -3990,G234C,-0.000311783,-0.0120545,-0.010929522,-0.00472517,-1.561572545,-0.05531149,-0.011105364,0.010481799,-0.017877536,-0.00267501,-0.02143399,-0.009981653,-0.011877391,0.054793874,-0.064244214,-1.703851245,-1.419293844,0.602591657,1.307261529,-10.43842499,-10.6162741,-10.30271465,-10.42190092,-10.52473339,-10.32650192,-9.185551772,-11.79063775 -3991,G234E,-0.045315113,-1.058921167,-1.977628526,-2.138036628,-2.321554784,-0.02033968,-0.028896897,-0.061733328,0.034228411,-0.878398813,-1.239443521,-1.946796501,-2.00846055,-1.748649069,-2.527424186,-2.205171078,-2.437938489,4.138613611,2.153247598,-10.39952753,-10.22866742,-10.42123166,-10.38530894,-10.66152987,-10.30089978,-9.177886845,-11.74813046 -3992,G234D,0.02294372,-1.588138586,-1.957331915,-2.38977404,-2.715611985,-0.081785481,0.017880819,0.028006621,-0.10343415,-1.703682407,-1.472594764,-1.872624392,-2.042039438,-1.866362487,-2.913185593,-2.658676597,-2.772547373,-0.272881496,-1.102085595,-9.770944043,-9.756021835,-9.948399704,-9.66662532,-9.822440353,-9.661233002,-8.137221204,-7.910816956 -3993,G234F,-0.013340527,-0.343604083,-1.679795354,-2.644369207,-2.606707788,-0.068570357,-0.020224715,-0.006456339,-0.009222664,-0.317924056,-0.36928411,-1.72990409,-1.629686617,-2.036906637,-3.251831776,-3.102222019,-2.111193556,1.409740339,0.071816329,-10.40542533,-10.51056316,-10.38879648,-10.30291407,-10.5271024,-10.29775055,-9.185551772,-11.79063775 -3994,G234I,0.017278238,-1.438260837,-2.029519955,-2.986973589,-2.648282175,0.017984054,0.049648539,-0.015092064,-0.11545232,-1.730005134,-1.14651654,-2.221166414,-1.837873496,-2.750017711,-3.223929466,-2.514303098,-2.782261251,-0.236967598,-1.106847969,-10.41925751,-10.50464202,-10.47195818,-10.39855775,-10.54267944,-10.17845016,-9.185551772,-11.79063775 -3995,G234H,-0.071572495,-1.554517198,-1.957400961,-2.747627718,-3.010996295,0.030767333,-0.06511952,-0.07802547,-0.065984071,-1.572287375,-1.53674702,-2.001300748,-1.913501173,-2.752000794,-2.743254642,-3.118346172,-2.903646418,-0.110587603,-1.027089495,-10.41854019,-10.27740331,-10.36786759,-10.49305637,-10.58521826,-10.36915543,-9.185551772,-11.79063775 -3996,G234K,-0.042857617,-1.562354054,-2.696519084,-2.509624587,-3.099599421,-0.031145079,-0.047132499,-0.038582735,-0.20298674,-1.773961003,-1.350747105,-2.130423709,-3.262614459,-2.4040025,-2.615246674,-3.247469133,-2.951729709,-0.118271563,-1.152899961,-10.45424748,-10.51528107,-10.50200573,-10.39123663,-10.57730575,-10.28540823,-9.185551772,-11.79063775 -3997,G234M,0.024403547,0.065914093,0.032693439,-0.120575122,-2.433627533,-0.090968558,0.022368109,0.026438985,-0.000881008,0.05171755,0.080110636,0.047564331,0.017822547,-0.073680226,-0.167470017,-2.261211487,-2.606043578,0.793066976,1.27769163,-10.39744546,-10.31026997,-10.25030527,-10.48635746,-10.58432303,-10.35597157,-9.185551772,-11.79063775 -3998,G234L,-0.014686451,-0.809411792,-2.084361637,-2.35050456,-2.699437057,0.01814068,-0.006376118,-0.022996783,-0.040923087,-0.778744711,-0.840078873,-2.325857396,-1.842865877,-2.326434915,-2.374574204,-3.044962812,-2.353911301,0.653942266,-0.542154185,-10.39558183,-10.46600101,-10.29216428,-10.35918356,-10.51693811,-10.34362217,-9.185551772,-11.79063775 -3999,G234N,-0.024967421,-0.609571955,-1.794934052,-2.569402284,-2.983285859,0.027463486,0.001740515,-0.051675357,-0.04314524,-0.474555127,-0.744588782,-1.935753184,-1.65411492,-1.862544489,-3.276260079,-3.131979854,-2.834591864,1.171064495,-0.19067294,-10.41985786,-10.41463962,-10.36607552,-10.43760779,-10.53366042,-10.34730596,-9.185551772,-11.79063775 -4000,G234Q,-0.047122136,-0.501619381,-2.015615443,-2.954174796,-2.478982746,0.002518225,-0.069684477,-0.024559794,-0.035789286,-0.412023635,-0.591215126,-2.293334679,-1.737896207,-2.52115598,-3.387193612,-2.489561349,-2.468404142,0.352765693,-0.474355865,-10.45483892,-10.46871574,-10.33889546,-10.56854253,-10.57324558,-10.32479527,-9.185551772,-11.79063775 -4001,G234P,0.002964446,-1.762234038,-2.241413739,-2.550705022,-3.176723071,0.033272983,-0.045932057,0.051860949,-0.205609947,-1.734257625,-1.79021045,-2.322328918,-2.16049856,-2.578178942,-2.523231102,-3.041434334,-3.312011808,0.150036361,-1.131681049,-10.46165855,-10.47306409,-10.29586998,-10.58253554,-10.58524729,-10.37157586,-9.185551772,-11.79063775 -4002,G234S,0.018120186,0.028404317,-0.015168879,0.028842321,-1.605763109,-0.077978752,-0.005472224,0.041712596,-0.045727847,0.02044486,0.036363773,-0.02933032,-0.001007438,0.040513183,0.017171458,-1.618313542,-1.593212675,0.748420535,1.318110479,-8.314960323,-8.306355858,-8.430583405,-8.257491631,-8.369066422,-8.211304298,-7.873708945,-7.54889086 -4003,G234R,-0.039126456,-1.714197457,-1.979766166,-2.435319155,-2.901957822,-0.020290877,-0.040068666,-0.038184245,-0.177344135,-1.810133982,-1.618260932,-1.927714599,-2.031817733,-2.440175479,-2.43046283,-3.061793362,-2.742122281,0.065340873,-1.11885147,-10.42583389,-10.46886327,-10.38482246,-10.41553636,-10.6061175,-10.25382987,-9.154490617,-11.37314356 -4004,G234T,0.031195985,-1.081721343,-2.046177788,-2.333037854,-3.329469367,-0.024475185,-0.017493792,0.079885762,0.003723069,-1.138875411,-1.024567274,-2.189344702,-1.903010873,-2.030221378,-2.63585433,-3.510510109,-3.148428624,0.401466038,-0.691296483,-10.39642932,-10.40357899,-10.4545721,-10.48048015,-10.48601909,-10.15749628,-9.185551772,-11.79063775 -4005,G234W,0.015597611,-1.58791409,-2.190788128,-2.204593901,-2.90549311,-0.00566266,0.025535132,0.005660089,-0.170899374,-1.50366106,-1.672167119,-2.052814286,-2.328761969,-2.171491118,-2.237696684,-2.838866492,-2.972119728,3.506104314,1.03420937,-10.45593116,-10.38541417,-10.53499925,-10.48162762,-10.54279255,-10.33482218,-9.185551772,-11.79063775 -4006,G234V,-0.02360701,-1.428594905,-1.948400499,-2.411244085,-2.74767668,-0.014247851,-0.016472026,-0.030741994,-0.07120542,-1.57919129,-1.277998519,-1.879538054,-2.017262943,-2.028178108,-2.794310061,-2.297613474,-3.197739886,-0.642684232,-1.094674652,-10.05566047,-10.12026865,-10.04816708,-10.02479716,-10.147808,-9.937261444,-8.867416258,-9.658166592 -4007,G234Y,-0.022137672,-0.158713071,-1.642958163,-2.083699918,-2.784599127,-0.044783243,-0.037154547,-0.007120796,0.003970054,-0.056540495,-0.260885646,-1.741753363,-1.544162962,-1.839240895,-2.328158941,-2.682707528,-2.886490725,0.648792352,-0.019361066,-10.4410924,-10.46052343,-10.34562449,-10.50005337,-10.5792486,-10.32001213,-9.185551772,-11.79063775 -4008,A235C,-0.028105971,0.075852876,0.044039948,-1.164923126,-2.08141988,-0.033883588,-0.001411115,-0.054800826,-0.027651207,0.119588018,0.032117733,0.049613015,0.038466881,-0.994322867,-1.335523384,-1.642554446,-2.520285313,2.731779829,2.08239639,-11.51819155,-9.462964745,-10.75461963,-10.25577422,-13.94590936,-13.17168981,-9.31986551,-3.809366403 -4009,A235E,-0.011691018,0.042006614,-0.210975093,-1.491859997,-2.072320436,-0.115152184,0.065705145,-0.089087181,-0.028445197,0.054009949,0.030003279,-0.130373288,-0.291576897,-1.445636858,-1.538083135,-2.330529066,-1.814111805,1.035496575,0.741344538,-11.6445981,-11.45084269,-9.773081894,-9.266075867,-13.85609575,-13.8768943,-8.520513183,-0.507266673 -4010,A235D,-0.09194124,0.042963841,-0.98416695,-1.647866272,-2.115127014,-0.092260351,-0.002120893,-0.181761587,-0.070047378,0.081630367,0.004297315,-0.789462329,-1.178871571,-1.700546393,-1.595186151,-2.471495248,-1.75875878,2.42351389,1.231798127,-11.72145004,-9.250252922,-10.55415818,-9.193722244,-16.13366814,-13.47544872,-8.021513392,-0.786022617 -4011,A235G,-0.015009855,0.041144591,-0.013612222,0.012796537,-0.195906278,0.451028253,0.016294393,-0.046314103,-0.07439092,0.059400771,0.02288841,-0.030114374,0.002889931,-0.029815038,0.055408112,-0.130233789,-0.261578766,1.346579957,2.22810876,-5.690745107,-4.832636856,-4.658793884,-4.18947393,-8.477126709,-6.295694153,-5.915240371,-0.868158387 -4012,A235F,-0.015331559,0.03564464,-0.908204115,-1.819743386,-2.731486801,-0.030949493,0.019764146,-0.050427263,-0.055287866,0.047752844,0.023536436,-0.747632971,-1.068775258,-1.586996245,-2.052490527,-2.562065083,-2.900908518,2.284111694,1.167200295,-13.04182528,-11.16146475,-11.78339207,-10.82954465,-17.05699033,-14.37773458,-8.378154134,-3.505429722 -4013,A235I,-0.021844543,0.047786776,-0.008456892,-1.101936247,-1.641532469,-0.091961225,0.01584725,-0.059536335,-0.054374899,0.101570387,-0.005996835,-0.012151725,-0.004762058,-0.822779236,-1.381093257,-1.92694277,-1.356122168,1.89680384,1.408201281,-11.36431353,-9.80933593,-10.22682204,-9.209547836,-13.16050863,-14.4153532,-8.853272695,-3.095008238 -4014,A235H,-0.050384711,0.029431236,-0.778441448,-1.777158094,-2.923896147,-0.055735862,0.021089311,-0.121858733,-0.067214244,0.03487308,0.023989392,-0.609849071,-0.947033825,-1.612279157,-1.942037031,-2.830386043,-3.017406251,1.952082072,0.964241472,-10.55989056,-9.558316498,-9.246012596,-7.980842041,-13.80185712,-12.21242457,-7.797509899,-3.218468263 -4015,A235K,-0.069329248,0.030898831,-0.772509265,-1.71371466,-2.459200878,-0.120691473,-0.019237598,-0.119420897,-0.070577009,0.011259392,0.050538269,-0.635551415,-0.909467114,-1.675653383,-1.751775936,-2.650722221,-2.267679535,2.096379378,1.022286191,-11.85066568,-11.42397823,-10.84323582,-10.72939079,-13.27336491,-12.98335863,-9.3451512,-5.171756881 -4016,A235M,-0.030704901,0.036352856,-0.016075435,0.008214469,-1.508882022,-0.081816068,0.006175024,-0.067584825,-0.092948532,0.034139164,0.038566547,-0.04925603,0.01710516,-0.009641839,0.026070776,-1.475860053,-1.54190399,0.675564488,1.321332518,-9.151767949,-8.516134201,-9.270973152,-7.862599861,-10.00388454,-10.10524799,-7.448986154,-2.583273555 -4017,A235L,-0.023488519,0.031821012,-0.019119744,-0.006719813,-1.561597794,-0.068352984,0.012323978,-0.059301015,-0.083658216,0.056100563,0.00754146,-0.042617992,0.004378504,-0.002002899,-0.011436726,-1.48139273,-1.641802858,0.615855202,1.317431963,-10.81891654,-8.122883705,-10.28008495,-8.975374649,-12.79539559,-13.92084379,-7.788868083,-2.294431207 -4018,A235N,-0.071027517,0.055404646,-0.035691518,-0.186416724,-1.827750319,-0.056930851,0.013257623,-0.155312657,-0.057936892,0.051813491,0.0589958,-0.073910402,0.002527366,-0.130714193,-0.242119255,-1.713833386,-1.941667251,1.078612738,1.33740563,-8.918599149,-7.147688484,-8.812515633,-7.648098869,-11.361973,-9.622719757,-6.915562288,-1.307764642 -4019,A235Q,-0.05467455,0.038408686,-0.008853839,-0.650255203,-1.865425273,-0.121890295,0.009034012,-0.118383112,-0.031702992,0.05812324,0.018694131,-0.023035929,0.005328252,-0.423974793,-0.876535613,-1.6857246,-2.045125945,1.677709855,1.460300213,-9.946223592,-11.52090428,-8.530738274,-7.891485741,-11.38268351,-10.40530615,-7.260708673,-2.69286917 -4020,A235P,-0.019429378,-1.424658577,-1.693481054,-1.810380772,-2.189950193,-0.055055467,-0.002005437,-0.036853318,-0.112747337,-1.329484613,-1.51983254,-1.541576694,-1.845385413,-1.582594574,-2.03816697,-1.672671647,-2.707228738,4.365761308,2.431379288,-12.32889045,-11.62655095,-11.11590831,-11.22559863,-14.50069403,-13.17570032,-11.38411299,-8.108516822 -4021,A235S,0.010401251,0.038181022,-0.003760595,0.003569439,-0.510609574,0.11061234,0.03386879,-0.013066289,-0.080925361,0.057690879,0.018671164,-0.026744092,0.019222903,-0.051418938,0.058557815,-0.260929322,-0.760289825,1.476019049,2.043273514,-3.999306398,-3.537286377,-3.784333702,-3.092589912,-5.590388886,-3.991933113,-5.205697961,0.494013866 -4022,A235R,-0.003625639,0.039144301,-0.309026689,-1.542878783,-2.200683192,-0.0472248,0.020704007,-0.027955284,-0.060735356,0.05183901,0.026449591,-0.225317994,-0.392735384,-1.382464269,-1.703293296,-1.900306681,-2.501059703,3.269304576,2.326429437,-10.06662275,-9.126002014,-9.874828049,-8.569979431,-10.74576675,-12.0165375,-7.17399448,-2.422895161 -4023,A235T,0.007971499,0.020406668,-0.022568178,-0.006645009,-1.25967584,0.156841218,-0.007806964,0.023749961,-0.042745024,0.036592242,0.004221094,-0.065863972,0.020727616,-0.05304959,0.039759572,-0.983146991,-1.536204689,1.792915159,1.790732247,-5.457007298,-5.945702766,-4.986124512,-5.456055023,-6.677488976,-4.219665215,-5.641632835,1.119527684 -4024,A235W,0.026176647,-0.209996459,-1.550406593,-2.022610254,-2.532248478,-0.082580418,0.072118029,-0.019764736,-0.046250848,-0.0207075,-0.399285418,-1.398632112,-1.702181073,-1.844663963,-2.200556545,-2.428526174,-2.635970781,3.080629419,1.554311802,-13.40710953,-9.876178841,-11.49637869,-11.84885735,-16.72697373,-17.08715905,-8.057920533,-1.371595226 -4025,A235V,-0.014581354,0.040542159,-0.011102751,-0.179605979,-1.726128457,-0.089288014,0.036944443,-0.066107151,-0.071727936,0.037455749,0.043628568,-0.030854651,0.00864915,-0.101908174,-0.257303783,-1.432731318,-2.019525596,0.672380861,1.321015457,-10.10180878,-9.59604171,-9.467636208,-9.095258812,-11.76497532,-10.58513186,-9.201091555,-4.421113662 -4026,A235Y,-0.065113656,0.008960559,-0.400849082,-1.627688272,-2.904926762,-0.072336026,0.010123797,-0.140351108,-0.043185095,0.01131384,0.006607278,-0.313201916,-0.488496248,-1.572147124,-1.683229419,-3.091284006,-2.718569517,1.417253447,0.789313408,-13.31970662,-11.3285424,-11.78512462,-10.7929362,-16.3608126,-16.33111727,-8.042284818,-3.293510926 -4027,G236A,0.054920385,-0.00786816,0.004194297,0.042776524,-0.236250409,1.404567681,0.04638718,0.063453589,-0.045242464,-0.009638205,-0.006098115,0.004062463,0.00432613,0.040932679,0.044620369,-0.130637802,-0.341863016,1.141619583,2.234523073,-5.990484657,-6.740699188,-6.198597778,-5.525183105,-6.328148323,-5.159794891,-5.378278074,-2.351335558 -4028,G236C,0.016168896,-0.035612003,-0.000123516,-1.557431733,-2.686057566,0.781797972,0.018799879,0.013537913,-0.085019102,-0.084841007,0.013617001,0.002486103,-0.002733135,-1.286967162,-1.827896303,-2.519368437,-2.852746694,0.75016782,0.725861924,-8.433650706,-9.119224792,-7.165339417,-8.499766029,-6.513357468,-10.87056583,-6.06093129,-3.699459731 -4029,G236E,-0.025605592,0.053935217,-0.342622748,-1.761089106,-2.712110453,0.948171594,-0.014127709,-0.037083474,0.001462491,0.072443761,0.035426672,-0.089704946,-0.59554055,-1.42759753,-2.094580682,-2.643608389,-2.780612516,0.883967682,0.726753262,-11.07687134,-12.66613824,-9.15596666,-9.795286308,-14.64418588,-9.122779594,-8.251645,-3.427835284 -4030,G236D,0.052633837,-0.00289657,-0.010938381,-0.728995961,-2.1808833,0.660405004,0.033892086,0.071375587,-0.027654295,-0.02923162,0.02343848,-0.055345889,0.033469128,-0.528218019,-0.929773902,-2.05842032,-2.303346279,1.596939691,1.340400937,-10.40868176,-13.51851229,-9.3929832,-7.689338188,-12.96562212,-8.476953011,-5.888396052,-3.270555224 -4031,G236F,0.023655225,-0.176764469,-1.514488812,-2.033961992,-2.955770327,-0.120594943,0.038494357,0.008816092,-0.052371447,-0.053879176,-0.299649762,-1.577250243,-1.451727381,-1.784279108,-2.283644876,-2.585316619,-3.326224034,4.1752143,2.531264474,-13.76695112,-15.03014908,-11.82020096,-11.61685472,-15.12153581,-15.24601501,-6.885241271,-3.156242219 -4032,G236I,0.05669484,0.013980635,-1.274034575,-1.817826323,-2.956919109,-0.043943384,0.06823079,0.045158889,-0.032207638,-0.020694114,0.048655383,-1.067759695,-1.480309454,-1.888328369,-1.747324276,-2.592455867,-3.321382351,2.503887582,1.134896822,-12.08687547,-14.26152103,-9.609776604,-11.97545664,-13.4790716,-11.10855147,-5.750241114,-1.541335072 -4033,G236H,0.04394105,-0.007799824,-0.560650643,-1.969638716,-1.988734383,-0.02552734,0.010353933,0.077528167,-0.112005342,-0.054633715,0.039034067,-0.23754148,-0.883759805,-1.838354394,-2.100923038,-2.241451896,-1.73601687,1.300201944,0.72294033,-14.04521766,-16.20570544,-13.49273473,-10.88203595,-15.84487952,-13.80073266,-9.574363502,-7.314840248 -4034,G236K,-0.0503228,-0.517090447,-1.928514672,-2.548317577,-2.771155907,-0.102233963,-0.116282401,0.015636801,-0.021413802,-0.227564365,-0.806616529,-2.198093463,-1.65893588,-2.258994292,-2.837640861,-2.361061799,-3.181250015,0.623919979,-0.301732494,-11.05469652,-13.38614217,-9.933208183,-8.818348557,-15.03904633,-8.09673735,-7.656752773,-4.512334836 -4035,G236M,0.076077303,0.02587162,-1.192713259,-2.152759463,-2.764673419,0.036579289,0.069925993,0.082228612,-0.057617519,0.038085311,0.013657928,-1.0454833,-1.339943217,-1.805354134,-2.500164792,-2.384542895,-3.144803942,2.863739462,1.49016366,-14.21205618,-16.05875796,-10.47703264,-13.76903478,-16.13063683,-14.6248187,-7.122014412,-3.868870879 -4036,G236L,0.003514004,-0.316142809,-1.651235634,-2.096764423,-2.99387687,-0.095184697,0.003738939,0.003289069,-0.045340653,-0.058677208,-0.57360841,-1.554426267,-1.748045001,-1.86199943,-2.331529416,-2.291425871,-3.696327869,3.79842667,2.192439685,-13.13020982,-13.29615464,-9.166885292,-12.9829286,-15.89587486,-14.30920568,-6.114824407,-0.74215118 -4037,G236N,0.084387894,0.028674557,0.002736551,0.03683882,-1.208769179,1.433825206,0.090863136,0.077912651,-0.001388963,-0.063372329,0.120721442,-0.008056802,0.013529903,-0.002580408,0.076258047,-1.154093974,-1.263444383,0.969611214,1.369024506,-8.81307034,-11.81098616,-9.346120369,-4.454513618,-11.99545193,-6.458279625,-5.109286281,-2.968751407 -4038,G236Q,0.038087266,-0.027078625,-0.807437958,-1.76236379,-3.07324775,0.415829072,0.069515338,0.006659194,-0.061340516,-0.01647346,-0.037683789,-0.489180799,-1.125695117,-1.583505384,-1.941222195,-2.685572891,-3.460922608,1.831040459,0.930176328,-11.01859875,-11.81768144,-9.766072563,-9.569935776,-14.43538501,-9.503918945,-6.895352105,-2.826695611 -4039,G236P,0.040972019,-1.76898324,-2.151777122,-2.287503711,-3.063569707,-0.122100721,0.028043194,0.053900843,-0.129893171,-1.9019066,-1.636059879,-2.262841289,-2.040712955,-2.365134803,-2.209872618,-2.512959801,-3.614179612,-0.303889358,-1.158243746,-9.695256825,-7.400000641,-8.576845589,-9.982379929,-11.06167657,-11.45538139,-6.376942011,-4.302170808 -4040,G236S,0.050618201,0.010690989,-0.01785845,0.003626732,-1.467128934,1.427252892,0.040005473,0.061230928,-0.029272728,-0.001738077,0.023120055,-0.016493109,-0.01922379,-0.012432857,0.019686321,-1.246408235,-1.687849633,1.299185752,1.444978243,-5.44332608,-6.441233025,-6.566121033,-3.66125499,-5.999168312,-4.548853043,-4.005352312,-3.120877891 -4041,G236R,-0.014763252,-0.622823398,-1.836555433,-2.049644833,-2.615893721,-0.056197104,-0.023457015,-0.006069489,-0.060476969,-0.33312123,-0.912525565,-1.797717131,-1.875393735,-1.983556697,-2.115732969,-2.562745459,-2.669041982,1.5362142,0.014015193,-11.92877893,-14.04647554,-10.93394056,-10.48732816,-13.38381291,-10.79233746,-7.908842576,-6.052350264 -4042,G236T,-0.001385194,-0.006117901,0.001107483,-0.03642424,-1.740199749,1.23885317,-0.010713827,0.007943439,-0.021668358,-0.02697369,0.014737888,-0.011837569,0.014052534,0.006286655,-0.079135134,-1.529101783,-1.951297714,1.052727119,1.330378607,-8.989255266,-9.760221771,-8.335565483,-7.561612602,-10.44659397,-8.842282501,-6.672785381,-4.594910333 -4043,G236W,-0.00414746,-0.360472496,-1.588372192,-2.078936274,-2.740907806,-0.083322945,0.000819758,-0.009114677,-0.025167383,-0.13143757,-0.589507421,-1.499123459,-1.677620924,-2.134055556,-2.023816992,-2.838183054,-2.643632558,0.964214948,0.061939857,-13.52776256,-13.89034081,-13.0498199,-12.00755156,-15.06000651,-13.63109402,-6.695678948,-4.416799003 -4044,G236V,-0.006881797,-0.037952103,-1.285161504,-2.291472977,-3.008813615,0.004531591,-0.004125752,-0.009637841,-0.046413915,0.03258214,-0.108486346,-1.202892346,-1.367430662,-2.485641925,-2.097304028,-3.064830687,-2.952796543,1.826665002,0.476396305,-11.52327332,-14.02641759,-10.52207693,-11.19530595,-11.29552094,-10.5770452,-6.462964239,-1.995438169 -4045,G236Y,0.004943683,-0.231872153,-1.774563795,-2.126810099,-2.977284682,-0.048244934,0.033344442,-0.023457076,-0.002219374,-0.029576826,-0.434167479,-1.557617771,-1.991509818,-1.986495385,-2.267124812,-2.565684147,-3.388885216,2.812348987,1.212091853,-14.01606773,-15.86405241,-13.79184651,-10.75937568,-14.81475333,-14.85031072,-6.704260028,-4.977186618 -4046,E237A,0.021780287,0.013122682,0.002696695,0.010723965,0.004358278,0.329409481,0.012706366,0.030854208,0.037742492,-0.004461775,0.030707139,0.026978215,-0.021584826,0.011727353,0.009720577,-0.000775916,0.009492471,1.190274632,2.681530754,-1.723000049,-1.042876999,-2.188456757,-2.101392014,-1.735931923,-1.546342552,-2.036443416,0.387706604 -4047,E237C,0.051736014,0.04806995,0.051035383,0.052475841,0.011073096,-0.01764537,0.058828335,0.044643693,0.015383121,0.060040358,0.036099542,0.095683344,0.006387422,0.046285668,0.058666013,0.003102715,0.019043477,1.265153065,2.758888417,-7.751953905,-7.498514572,-8.854867561,-8.580556892,-8.264492996,-5.561337502,-6.385090407,-3.783039406 -4048,E237D,0.129920762,0.047613035,0.034996803,0.030155653,0.066875465,0.04395571,0.135514281,0.124327243,0.00324197,-0.000536259,0.095762328,-0.013446969,0.083440574,-0.014215956,0.074527261,-0.017419855,0.151170784,1.189624685,2.483117129,-1.008859439,-0.504138275,-0.926914223,-1.016697464,-1.816116844,-0.780430389,-1.644379766,1.175356731 -4049,E237G,0.037270041,0.020322382,0.005767482,0.02180569,0.008001971,0.767314282,0.03854652,0.035993561,0.005855366,0.018844459,0.021800305,0.024400153,-0.01286519,0.011386369,0.03222501,0.007929292,0.00807465,1.087272543,2.825132521,-0.63343844,-0.685592117,-1.529242249,-0.112332275,-1.308316971,0.468291412,-0.889596079,1.252001601 -4050,E237F,0.153724933,0.049986438,-0.02540932,0.055841656,0.022973874,-0.066171618,0.179112722,0.128337143,0.047476287,0.004503379,0.095469497,-0.004950031,-0.045868609,-0.0021272,0.113810511,-0.035525883,0.081473631,1.304347324,2.554738565,-7.826209393,-7.786741249,-9.531871574,-7.6341567,-7.511129974,-6.667147469,-3.923115408,-1.488799733 -4051,E237I,0.039466995,0.000513951,-0.022627027,0.00763736,-0.278604064,0.213064549,0.041194267,0.037739723,0.028992881,-0.027712941,0.028740842,-0.02247539,-0.022778663,-0.047730055,0.063004775,-0.247763756,-0.309444372,1.085590718,1.784116956,-8.474566351,-6.287865906,-10.72831259,-9.400867172,-8.503458237,-7.45232785,-4.555756074,-0.245710896 -4052,E237H,0.011325577,0.055101766,0.007777483,0.033230232,0.017693319,0.079610919,0.001441493,0.02120966,0.006749528,0.066766089,0.043437442,0.050909533,-0.035354568,0.060711483,0.00574898,0.040326054,-0.004939416,1.113349719,2.638047589,-4.984220873,-4.724647827,-5.518680847,-4.722360977,-5.429035751,-4.52637896,-4.106831979,-1.617709987 -4053,E237K,-0.008818906,0.020584535,0.008749543,0.00207233,0.020351337,0.024162714,-0.015203081,-0.00243473,0.014449873,0.019235199,0.02193387,0.052596433,-0.035097348,0.01643458,-0.01228992,0.027386275,0.013316399,1.192568025,2.796023765,-1.880495392,-1.283476852,-1.420520531,-2.385920547,-2.256177727,-2.056381302,-1.708415899,-1.12334336 -4054,E237M,-0.024339267,-0.001607612,-0.027492539,-0.005991746,-0.01660617,0.044449022,-0.012518659,-0.036159875,0.035613181,-0.04898579,0.045770566,0.028665851,-0.083650928,-0.029932473,0.017948981,0.002606818,-0.035819158,1.267990563,2.835683017,-7.339254633,-6.645161407,-7.990439049,-8.980987473,-6.923070572,-6.156614662,-4.405676593,-1.120437912 -4055,E237L,0.022531059,-0.003476843,-0.010275342,0.025241642,0.02178387,-0.016616727,0.041051223,0.004010894,0.015236014,-0.003818071,-0.003135615,0.037017276,-0.05756796,0.023981534,0.02650175,0.024727497,0.018840242,1.195692299,2.706288723,-7.630595923,-6.348345528,-8.29258593,-9.646323921,-8.501368141,-5.364356094,-4.219657555,0.291238382 -4056,E237N,0.062287568,0.027558955,0.01971382,0.026362486,0.028963159,0.213054033,0.08783974,0.036735396,0.021612083,0.041625729,0.01349218,0.034456916,0.004970723,0.002279997,0.050444974,0.001333337,0.05659298,1.13577818,2.546115788,-1.539078392,-0.962950317,-1.571006073,-1.57174353,-1.974481613,-1.615210426,-2.526897133,0.044551579 -4057,E237Q,0.055866474,0.013583835,0.027046884,0.049372207,0.031464553,-0.098277772,0.073977456,0.037755491,-0.031869808,0.026299358,0.000868311,0.065337106,-0.011243339,0.053420194,0.04532422,0.052932038,0.009997068,1.15149873,2.845930259,-2.914351137,-2.552410797,-3.052184479,-2.707819725,-2.899610512,-3.359730171,-4.331324636,-0.91444466 -4058,E237P,0.064673047,0.016898097,0.01298529,0.045290303,0.01334188,0.879597561,0.061122111,0.068223983,0.002832723,-0.014535569,0.048331762,0.014018847,0.011951733,-0.008556986,0.099137592,-0.007948202,0.034631962,1.190206942,2.541524194,-5.711589749,-3.336375763,-7.32109021,-6.720326889,-5.469748268,-5.710407616,-3.498589167,0.449849744 -4059,E237S,0.044308005,0.012462466,-0.024124835,-0.005290478,-0.047764578,0.325162794,0.033265859,0.05535015,0.001883178,0.024343557,0.000581374,-0.008667625,-0.039582044,-0.019850134,0.009269179,-0.012465406,-0.083063749,1.191086666,2.517326855,-2.107324828,-1.815759651,-2.125610115,-2.863621536,-3.10025209,-0.631380745,-2.502537181,0.606592479 -4060,E237R,0.045530611,0.040534671,0.03014494,0.030740914,0.028908156,0.106256456,0.05354264,0.037518581,-0.009808532,0.023388678,0.057680663,0.043868082,0.016421797,0.014723341,0.046758487,0.005038931,0.05277738,1.235410105,2.707092308,-3.365331976,-2.466971169,-4.167800461,-3.352641388,-3.713146545,-3.126100319,-2.301821628,0.063660658 -4061,E237T,0.022768817,0.033842372,-0.007626198,0.019304304,-0.086835761,0.424383682,0.023216423,0.02232121,0.002117415,0.040711318,0.026973425,0.03670994,-0.051962335,0.011794448,0.026814159,-0.043992692,-0.12967883,1.35872297,2.542566953,-4.79134041,-3.460786819,-5.216501785,-6.679636238,-5.567997635,-3.031779572,-3.03943117,0.236758602 -4062,E237W,0.000430592,0.007982886,0.00551169,0.040974098,-0.023706336,0.036092106,-0.002647093,0.003508277,0.028590943,0.041132231,-0.025166459,0.037607092,-0.026583713,0.060072903,0.021875292,-0.023614723,-0.023797948,1.148176074,2.62011901,-8.419979745,-7.7947388,-10.06187313,-8.679413231,-8.243644295,-7.320229271,-4.769548245,-2.249789037 -4063,E237V,0.016657895,0.016246553,-0.003499815,0.005257035,-0.232596251,0.150908039,0.0230627,0.010253089,0.031151224,0.01142821,0.021064895,-0.014502397,0.007502767,0.010829596,-0.000315526,-0.167832723,-0.297359778,1.286751929,2.152541439,-6.363935059,-4.646724037,-8.195306038,-6.95441021,-5.924248207,-6.098986801,-3.443371904,-0.231129154 -4064,E237Y,0.03468529,0.03167615,-0.022749236,-0.002681862,0.005440546,-0.018638248,0.027268042,0.042102537,-0.033591441,0.039892097,0.023460202,0.027770463,-0.073268935,-0.019408778,0.014045055,0.022172346,-0.011291254,1.269385316,2.738699336,-7.294705696,-7.142991142,-8.348777092,-7.013015953,-7.073973236,-6.894771057,-4.59982177,-1.749711093 -4065,R238A,0.013523674,-0.006739704,0.005233807,0.001631919,-0.191382774,0.103106836,0.002081165,0.024966183,-0.044662852,-0.00037826,-0.013101148,0.019600328,-0.009132715,0.010257354,-0.006993516,-0.119725788,-0.263039759,1.354717853,2.295813115,,,,,,,, -4066,R238C,0.006360838,-0.033718128,0.006770052,0.013370802,-0.055273876,0.107010355,-0.018394177,0.031115853,-0.023119319,-0.070497449,0.003061194,-0.004808982,0.018349086,0.000221862,0.026519741,-0.062240653,-0.048307099,1.441343202,2.542119829,,,,,,,, -4067,R238E,-0.022968665,0.029692102,-0.023085343,-0.059469499,-0.540561517,0.045035146,-0.011106481,-0.034830848,-0.060319006,0.082152486,-0.022768283,-0.05078478,0.004614095,0.00618871,-0.125127707,-0.311253214,-0.76986982,1.363344988,1.921643466,,,,,,,, -4068,R238D,0.044063275,-0.041944485,0.033812808,0.025038282,-1.57260576,0.185830713,-0.0367761,0.12490265,-0.054581578,-0.098767298,0.014878328,0.013282005,0.054343611,0.037357839,0.012718724,-1.253680672,-1.891530847,0.696717712,1.336287943,,,,,,,, -4069,R238G,0.061826717,-0.012828113,0.006560023,-0.014056144,-0.100300886,0.115511891,0.039793422,0.083860012,-0.032907646,-0.030005061,0.004348835,-0.019326799,0.032446844,-0.030106625,0.001994337,-0.082427658,-0.118174113,1.31083945,2.315669824,,,,,,,, -4070,R238F,0.029527999,-0.014591693,0.059428278,0.020046416,-0.104102089,-0.00254995,-0.024329616,0.083385613,-0.111149608,0.041871951,-0.071055336,0.085747004,0.033109551,0.023702958,0.016389874,0.070243931,-0.278448109,1.118628365,2.914811813,,,,,,,, -4071,R238I,-0.009540119,0.079585897,-0.014749941,0.041987145,-0.699698682,0.145213541,-0.089008089,0.069927852,-0.005096215,0.069858655,0.089313139,0.060677993,-0.090177874,0.089162945,-0.005188655,-0.503501711,-0.895895652,0.682807408,1.435624382,,,,,,,, -4072,R238H,0.055715427,0.050251504,0.02029348,0.036135912,0.0399595,0.087740469,0.059939838,0.051491015,-0.02407681,0.029860569,0.070642438,0.049718325,-0.009131366,0.046613046,0.025658777,0.062834074,0.017084925,1.137440462,2.850695777,,,,,,,, -4073,R238K,0.086896117,-0.114179264,-0.058299687,-0.024551468,-0.166125883,-0.137545159,-0.016167021,0.189959254,0.038369479,-0.164810249,-0.063548279,-0.107726438,-0.008872935,-0.164904859,0.115801923,-0.144871436,-0.18738033,1.530227579,2.223333959,,,,,,,, -4074,R238M,0.074507152,-0.154587341,-0.077156442,-0.041714798,-0.112249205,0.011998869,0.03281944,0.116194864,-0.02737261,-0.231419722,-0.077754959,-0.145913983,-0.0083989,-0.095294585,0.01186499,-0.141202058,-0.083296352,1.433930912,2.17447863,,,,,,,, -4075,R238L,0.040988432,0.014057097,0.035478593,0.010212888,-0.168120586,0.033932266,0.04165778,0.040319083,-0.008836126,0.018096191,0.010018002,0.042315937,0.028641248,0.023301656,-0.002875881,-0.090550853,-0.245690318,1.383177731,2.37551118,,,,,,,, -4076,R238N,-0.034636479,-0.095317611,-0.04953162,-0.095589699,0.034922647,-0.08682265,-0.063993816,-0.005279142,-0.285922825,-0.061269657,-0.129365564,0.026167142,-0.125230381,-0.045718451,-0.145460946,0.053785651,0.016059642,1.192579612,2.685602053,,,,,,,, -4077,R238Q,0.103581896,0.025034679,0.050150416,-0.021896667,0.025892083,0.026169811,0.093168389,0.113995403,-0.089917729,-0.010092898,0.060162256,0.001743756,0.098557075,-0.039335155,-0.004458178,-0.021182192,0.072966358,1.228637379,2.520725081,,,,,,,, -4078,R238P,0.024899538,-0.007326929,0.000359611,-0.008658734,-0.416091557,1.085101182,-0.003829009,0.053628085,-0.042972249,-0.016926088,0.002272231,-0.020907237,0.021626458,-0.030461752,0.013144285,-0.246293323,-0.585889791,1.376820247,2.021028686,,,,,,,, -4079,R238S,-0.002756799,-0.01001807,-0.009010505,-0.008344181,-0.155113138,0.078984082,-0.030310274,0.024796677,-0.001410526,-0.004014583,-0.016021556,-0.009939947,-0.008081063,-0.004823018,-0.011865343,-0.075726208,-0.234500067,1.308196117,2.375946186,,,,,,,, -4080,R238T,0.007056598,-0.045825303,-0.058790893,-0.001321517,-0.338669016,0.165629506,-0.019518857,0.033632053,-0.0122748,-0.053517922,-0.038132683,-0.07866858,-0.038913206,-0.010637844,0.007994811,-0.205334419,-0.472003613,1.393653133,2.178452388,,,,,,,, -4081,R238W,0.007660385,-0.034941222,-0.037390028,-0.021497793,-0.043960948,0.035100761,-0.016887244,0.032208014,0.043752352,-0.047431335,-0.022451109,-0.04863501,-0.026145045,-0.005317684,-0.037677902,-0.05022631,-0.037695585,1.283728439,2.377140616,,,,,,,, -4082,R238V,-0.00942627,-0.021076475,-0.053167945,-0.049975949,-0.238486991,0.147413468,-0.016366651,-0.002485889,-0.007346451,0.000286821,-0.042439771,-0.010937584,-0.095398305,-0.034737604,-0.065214293,-0.169314658,-0.307659324,1.231832495,2.019396992,,,,,,,, -4083,R238Y,0.020920824,-0.014267013,0.097452303,0.095098628,-0.015876186,-0.013467264,0.00688754,0.034954107,0.044591569,0.127642224,-0.156176249,0.149450274,0.045454332,0.207093455,-0.0168962,0.060718242,-0.092470614,1.058071436,2.846765438,,,,,,,, -4084,G239A,0.001909976,0.004666123,-0.007806648,-1.047147798,-1.979592571,0.023000187,0.000558151,0.0032618,0.051486983,0.008320057,0.001012189,-0.014491599,-0.001121697,-0.508032231,-1.586263365,-1.930094193,-2.029090948,1.703047689,1.40304414,-6.350715509,-5.377266525,-11.35179063,-6.200394478,-4.76135936,-4.062766548,-4.913885982,-1.533644847 -4085,G239C,-0.021357437,-0.004849238,-0.056632231,-1.474953956,-2.428144581,-0.071174405,-0.055634137,0.012919264,0.039722138,-0.018669349,0.008970874,-0.02462764,-0.088636822,-1.197072243,-1.752835669,-2.303303751,-2.55298541,0.635493639,0.722194184,-11.58346454,-11.09735013,-15.85688959,-10.6822898,-10.99899721,-9.281795952,-8.897488482,-5.355894638 -4086,G239E,-0.046728088,-0.183592544,-1.389513556,-1.875562709,-2.076001008,0.078745305,-0.01528748,-0.078168695,0.001887984,0.001696793,-0.36888188,-1.30268419,-1.476342922,-1.771611161,-1.979514256,-2.208835888,-1.943166128,3.627298362,2.176036025,-9.484589391,-8.966725922,-14.24223277,-8.394125603,-9.710336716,-6.10952594,-7.027869214,-3.738354693 -4087,G239D,0.008714311,0.019566746,-1.106492416,-1.989329982,-2.963216949,0.00341126,-0.002640261,0.020068882,0.01605822,0.024738057,0.014395435,-0.897809746,-1.315175086,-1.733896391,-2.244763572,-2.840127899,-3.086305998,2.244188773,1.03832865,-8.413449467,-8.218256493,-11.30835925,-8.265688042,-8.939020889,-5.335922668,-6.532757759,-2.761592932 -4088,G239F,0.03096675,0.035093196,-1.186166216,-1.946611315,-2.215813547,0.037685815,0.026160932,0.035772567,-0.036707497,0.092619223,-0.022432831,-1.188040125,-1.184292307,-1.85533475,-2.03788788,-1.961566258,-2.470060835,3.458641408,2.097905365,-11.25213823,-13.44058752,-15.04146086,-9.710364609,-11.55474697,-6.513531181,-7.41124219,-4.01969675 -4089,G239I,-0.015741086,-1.179491697,-2.043695784,-2.249033143,-2.367720376,-0.078508564,-0.051316416,0.019834245,-0.087311424,-0.852056512,-1.506926882,-2.070567953,-2.016823614,-2.436832582,-2.061233703,-2.54306409,-2.192376662,1.302751413,-0.360332075,-11.00331891,-11.82043075,-14.49402286,-9.362343376,-10.31694462,-9.022852928,-7.269116039,-2.929441441 -4090,G239H,0.016120136,0.059149051,0.030095353,-1.496575198,-2.583425034,0.246990434,0.004310963,0.027929309,0.00530115,0.073596622,0.04470148,0.069778487,-0.009587781,-1.223465204,-1.769685191,-2.350886011,-2.815964057,0.607508039,0.717202443,-8.400404692,-9.615749603,-12.27359203,-6.284553505,-9.935687675,-3.892440651,-5.828385311,-2.984032047 -4091,G239K,0.036394657,-0.009619633,-1.058105408,-2.422242315,-2.852554194,0.038310036,0.033558543,0.039230771,0.006894531,-0.073348831,0.054109565,-0.798726347,-1.317484469,-2.395439897,-2.449044733,-2.501671405,-3.203436983,1.035420741,0.229645805,-10.18408251,-11.18211419,-12.71559509,-8.458586151,-10.91053208,-7.653585014,-8.190356716,-3.524643121 -4092,G239M,0.036952763,0.031896943,-1.312052359,-2.402990913,-2.866776187,0.109325022,0.058943199,0.014962327,0.024374446,0.022849341,0.040944544,-0.995190771,-1.628913947,-2.551787098,-2.254194728,-2.35698861,-3.376563763,0.545870292,0.102829382,-12.80048397,-13.15707536,-16.15085905,-11.9571353,-11.9995137,-10.73783642,-8.647575983,-5.235175498 -4093,G239L,-0.02939842,-0.602164272,-1.905582694,-2.104050147,-2.898614068,-0.012302918,-0.032824812,-0.025972027,0.017877257,-0.24944009,-0.954888454,-1.779297795,-2.031867593,-2.119233485,-2.088866809,-2.552823927,-3.244404208,1.063726662,-0.016636608,-12.2880638,-12.83794054,-14.78584284,-11.50994907,-12.47366219,-9.832924385,-8.058226907,-4.88891888 -4094,G239N,-0.046394232,-0.080821127,-0.062074112,-0.343966332,-1.935226949,0.230407045,-0.023459942,-0.069328521,-0.09949,-0.098329861,-0.063312392,-0.027820214,-0.096328009,-0.095089017,-0.592843646,-1.529700129,-2.340753768,0.887539729,1.334847964,-7.345668886,-7.832332542,-10.0533922,-5.460829338,-7.662952934,-5.71883741,-5.782938698,-2.257144277 -4095,G239Q,-0.051212267,-0.004606337,-0.60027163,-1.855041404,-2.958203478,0.070802197,-0.051690608,-0.050733925,-0.032725726,-0.020488416,0.011275743,-0.281645552,-0.918897707,-1.591873051,-2.118209756,-2.675828164,-3.240578791,1.417485572,0.788285311,-9.250107823,-10.18820316,-13.6929044,-7.088618813,-9.699257843,-5.581554901,-6.663909406,-3.6406527 -4096,G239P,-0.030044671,-0.788468433,-2.005819984,-2.326861082,-3.013732415,-0.017026849,-0.035005921,-0.025083421,0.046021443,-0.480416444,-1.096520422,-1.998481524,-2.013158443,-2.252772394,-2.40094977,-2.622245336,-3.405219493,1.297052199,-0.110112464,-11.14717653,-10.63579541,-14.99861381,-11.46005156,-10.27268575,-8.36873613,-7.3783663,-3.733063326 -4097,G239S,-0.036318762,-0.006397342,-0.040629764,-0.888703372,-2.061764239,0.358706493,-0.018824063,-0.05381346,0.049168518,0.004046582,-0.016841266,-0.015057124,-0.066202404,-0.265788572,-1.511618172,-1.826062177,-2.297466301,1.308435001,1.352249773,-8.687387048,-8.043391243,-13.61787285,-7.759276695,-6.483983467,-7.532410988,-6.377914687,-2.595907263 -4098,G239R,-0.022864891,0.004651346,-1.069065344,-1.850444295,-2.175100285,0.025220658,-0.0144523,-0.031277481,0.024959625,0.015781532,-0.00647884,-0.71787804,-1.420252648,-1.779146486,-1.921742103,-2.120590704,-2.229609866,3.322913849,2.073012482,-8.846759004,-9.79658989,-12.24630949,-7.275723396,-9.936254005,-4.978918236,-6.390762218,-2.592075141 -4099,G239T,0.000668261,0.031157401,-0.95836082,-1.971784833,-2.909216932,0.206584023,0.001641483,-0.000304961,-0.00097512,0.012907822,0.04940698,-0.535076838,-1.381644801,-1.745437674,-2.198131992,-2.439940888,-3.378492975,1.77124818,0.854888028,-8.362096638,-7.507867203,-13.28994987,-7.436592484,-6.364152954,-7.211920677,-7.116554287,-2.331966742 -4100,G239W,-0.049992484,-0.516454345,-1.854888405,-2.104785648,-2.344991906,0.051244985,-0.02385856,-0.076126407,0.069411578,-0.159360076,-0.873548614,-1.852415349,-1.85736146,-2.253442085,-1.956129211,-2.359673592,-2.33031022,0.823901656,-0.052810498,-13.02576905,-13.61643104,-16.32357917,-12.4180429,-12.83293024,-9.937861908,-9.041201555,-5.938691254 -4101,G239V,-0.012061086,-0.801233897,-1.868598154,-2.138702757,-2.429759452,0.032445619,-0.00247561,-0.021646561,0.101497129,-0.522029896,-1.080437898,-1.958504547,-1.77869176,-2.098372799,-2.179032714,-2.563626249,-2.295892655,1.376463075,-0.082802041,-9.77251927,-10.64894082,-13.79351885,-8.636477005,-9.257847115,-6.525812561,-6.724674695,-3.51152626 -4102,G239Y,0.054137136,-0.009956839,-1.214222587,-2.220589942,-2.951931816,0.058547232,0.067656421,0.040617851,0.088485139,0.085813936,-0.105727613,-1.193032071,-1.235413103,-1.985265432,-2.455914451,-2.568618195,-3.335245437,0.375886409,0.066190238,-10.54996781,-11.45608288,-14.96842617,-9.600451653,-10.84251923,-5.882359138,-7.200926403,-3.664997576 -4103,S240A,0.014647166,0.04287168,0.011648671,-0.003480665,-0.022943869,-0.003432627,0.004032195,0.025262137,-0.04204393,0.027697431,0.058045929,-0.008074391,0.031371733,-0.038474292,0.031512962,-0.032764675,-0.013123063,1.263908535,2.456590378,-2.248778029,-1.708949036,-1.904252693,-1.935560425,-2.958933159,-2.736194832,-3.015460112,0.345458359 -4104,S240C,0.037620546,0.070984486,0.023259807,0.024609858,-0.932433747,0.178414471,0.037692435,0.037548657,-0.043728504,0.072649436,0.069319536,0.026033663,0.020485951,-0.016076214,0.06529593,-0.491421849,-1.373445645,0.839613556,1.489518414,-9.056184189,-9.111981422,-8.763100464,-7.374000671,-11.14231943,-8.889518959,-7.31732263,-2.909057907 -4105,S240E,-0.076451975,0.059229322,0.023507772,0.054374492,-0.725830676,0.054118166,-0.132496507,-0.020407442,0.054115446,0.087686337,0.030772307,0.004387366,0.042628178,0.017873368,0.090875615,-0.48484489,-0.966816461,0.835740297,1.490933173,-8.748148415,-8.666740509,-7.530206932,-8.652781731,-10.45845785,-8.432555054,-6.027861883,-2.132577997 -4106,S240D,-0.053387797,0.026452073,-0.027099816,-0.124852755,-1.862349445,0.264060923,-0.09368,-0.013095594,0.071766978,-0.007555681,0.060459827,-0.071224761,0.017025129,-0.030568436,-0.219137073,-2.00480407,-1.719894819,0.855744859,1.302890282,-10.43915103,-10.61284664,-10.40271841,-9.27614447,-12.30038206,-9.603663574,-7.692835923,-3.852939978 -4107,S240G,0.022606177,0.023675744,-0.006154675,0.003864387,-0.030204569,0.418316457,-0.023578521,0.068790874,-0.022554106,0.023016395,0.024335093,-0.045312058,0.033002708,-0.012523933,0.020252706,-0.061926687,0.00151755,1.388676475,2.495855297,-5.092763226,-4.24506588,-3.365251045,-4.140007759,-6.671947418,-7.041544029,-5.765593895,-0.897641564 -4108,S240F,-0.029228062,0.005170654,-0.212806845,-1.82511757,-2.178369208,-0.073445529,-0.033065847,-0.025390276,-0.030720494,-0.009267376,0.019608683,-0.115971088,-0.309642602,-1.728527277,-1.921707863,-2.225641657,-2.131096759,1.004807804,0.705535844,-11.51816847,-12.23535089,-11.00720971,-9.617896446,-15.73242104,-8.997964249,-6.793336011,-2.558892643 -4109,S240I,0.041438765,-0.476190251,-1.96507792,-2.212159014,-2.406031271,0.052659733,0.038363578,0.044513951,-0.116881094,-0.171834032,-0.780546469,-1.592484513,-2.337671326,-1.97973142,-2.444586608,-2.078905791,-2.73315675,4.058217474,2.391368569,-9.741262784,-11.00340344,-10.71112164,-8.368944115,-12.24118104,-6.381663689,-5.062078138,-0.360292059 -4110,S240H,-0.014579481,0.009177225,-0.041348351,-0.005660976,-1.796794282,0.005638745,-0.029473552,0.00031459,-0.0465464,-0.048846336,0.067200785,-0.104320937,0.021624236,-0.075866599,0.064544648,-1.620125992,-1.973462571,0.968150187,1.334553966,-11.66624361,-12.01230915,-10.89983774,-8.19810537,-15.58468805,-11.63627774,-7.058853111,-3.327663408 -4111,S240K,-0.006614773,-0.147587833,-1.638797955,-1.735364052,-2.27872131,-0.184902379,-0.022698785,0.00946924,-0.006074148,0.085290478,-0.380466144,-1.71742325,-1.560172659,-1.803640161,-1.667087942,-1.902814532,-2.654628088,4.274744622,2.692923749,-11.83511694,-10.10433186,-9.525652115,-10.22950117,-15.12778197,-14.18831757,-7.0467582,-2.611570104 -4112,S240M,-0.053300474,-0.02908226,-0.03242939,-1.955336179,-2.600753429,0.013747405,-0.064077336,-0.042523611,-0.124017645,0.050305118,-0.108469638,-0.02047205,-0.04438673,-1.207920348,-2.70275201,-2.210184705,-2.991322152,2.226515296,1.43697974,-10.78746736,-10.63642024,-9.239874649,-10.01712814,-14.80271816,-9.241195587,-6.232574323,-1.705254053 -4113,S240L,-0.006525895,0.012265039,-1.211545501,-1.9746876,-2.888226204,-0.013294256,-0.003489258,-0.009562531,-0.022362985,0.049355947,-0.02482587,-1.056747773,-1.366343228,-2.015385851,-1.933989349,-2.678831653,-3.097620754,2.258446528,0.920188867,-12.04377773,-12.65058064,-11.58836924,-10.49254511,-16.40961912,-9.077774536,-7.056188848,-0.314701814 -4114,S240N,-0.106726605,-0.018215751,0.031108011,-0.097609826,-0.913859267,0.055278325,-0.166567738,-0.046885471,-0.017490732,-0.139649349,0.103217847,-0.02722717,0.089443192,-0.20158017,0.006360519,-1.057716492,-0.770002041,1.511656089,1.566086053,-7.758796129,-7.930515465,-6.327952942,-5.364080521,-12.32642848,-6.845003235,-5.118234987,-2.61397371 -4115,S240Q,-0.0092215,0.051296904,0.033281614,-0.003220548,-1.606006606,0.156544485,-0.008838861,-0.009604138,-0.082614422,0.046269431,0.056324376,0.021529292,0.045033936,0.011700727,-0.018141822,-1.527682816,-1.684330395,0.485066141,1.309037037,-11.71454063,-10.59190579,-10.6310981,-10.55950613,-15.18730841,-11.60288471,-6.758813166,-3.296063472 -4116,S240P,-0.012011325,-0.136174601,-1.40660669,-2.118872495,-2.754828369,-0.0084976,-0.041459759,0.017437109,-0.035910033,0.012437905,-0.284787106,-1.282362413,-1.530850966,-2.115131588,-2.122613402,-2.617998297,-2.891658441,0.94060404,0.096316325,-10.80836781,-10.11033876,-12.0477924,-9.181198708,-12.45706288,-10.24544629,-7.456460938,-3.316222515 -4117,S240R,0.004842682,-0.00639161,-1.198689776,-2.192751031,-2.648062661,-0.066925953,-0.021888534,0.031573898,-0.061003789,0.004082284,-0.016865504,-0.910675199,-1.486704352,-2.252164615,-2.133337447,-2.874217732,-2.421907589,1.817958207,0.633341086,-13.88855818,-13.01731786,-14.78807972,-11.08666785,-15.87378561,-14.67693988,-6.608010375,-1.206850116 -4118,S240T,-0.017192359,0.027964719,0.002360835,-0.039387726,-1.164781075,0.016033072,-0.029957951,-0.004426766,0.007286991,0.037142385,0.018787052,-0.005458825,0.010180494,-0.025979916,-0.052795536,-0.896674959,-1.43288719,0.775985507,1.379658729,-2.821457811,-2.539737953,-3.408808846,-2.014898308,-2.857323547,-3.286520401,-3.0597334,0.6761057 -4119,S240W,-0.019713187,-0.758188772,-2.171904949,-1.971657634,-2.353095749,-0.029746583,-0.02961271,-0.009813663,-0.052197756,-0.501573151,-1.014804393,-2.640789193,-1.703020705,-1.948854853,-1.994460414,-2.826180475,-1.880011022,0.258771612,-0.51517389,-14.25278716,-14.24157705,-13.91144769,-12.12958925,-17.0298372,-13.9514846,-8.28740065,-4.297872638 -4120,S240V,0.032684209,0.007553882,-1.030665821,-1.764126733,-2.206336385,-0.032732374,0.019903791,0.045464626,-0.014043077,-0.024607969,0.039715733,-0.62187966,-1.439451982,-1.899982097,-1.628271369,-2.351338986,-2.061333784,1.865558038,0.83584986,-8.76306546,-9.826564095,-10.60326877,-7.805614471,-9.950149193,-5.629730774,-4.833311757,0.496939597 -4121,S240Y,0.075639975,0.064536737,-0.46994701,-1.497578797,-2.128981685,-0.104078707,0.069139836,0.082140114,-0.062555504,0.01900028,0.110073194,-0.168910993,-0.770983027,-1.448252503,-1.54690509,-2.246396878,-2.011566491,1.107778403,0.752334956,-11.75838981,-12.28574372,-10.59578602,-8.527073067,-15.88397907,-11.49936717,-6.59638858,-2.959096153 -4122,R241A,0.034593009,0.033313734,0.040180392,-1.320427949,-2.091627551,-0.119690093,0.043031812,0.026154205,-0.022570501,0.061585445,0.005042023,0.057419459,0.022941324,-1.017667081,-1.623188816,-1.970118682,-2.21313642,3.21787308,2.42544262,-11.30024273,-13.03533869,-10.54232766,-8.91739196,-11.60693608,-12.39921925,-5.44537278,-0.956594715 -4123,R241C,-0.031404205,0.051584706,0.029209912,-1.173632658,-1.452284211,-0.078900874,-0.036839687,-0.025968723,-0.038881485,0.103441079,-0.000271667,0.140636075,-0.082216251,-0.873341807,-1.473923508,-1.465641961,-1.438926461,3.259127358,2.684509563,-12.85110836,-11.94312028,-11.47337929,-12.55052983,-13.47295764,-14.81555478,-7.517223019,-3.01295916 -4124,R241E,0.014826033,-0.015203806,-0.427549172,-1.558659032,-2.959300658,-0.07513953,0.021140309,0.008511757,-0.008482633,-0.004016025,-0.026391587,-0.084706633,-0.77039171,-1.522127223,-1.59519084,-2.237666329,-3.680934986,0.919229884,0.716212843,-13.73643701,-17.51842941,-11.94104588,-11.82236833,-14.76764871,-12.63269271,-7.500102304,-1.643547027 -4125,R241D,0.01745611,-0.076117713,-1.165886901,-2.563756685,-2.651565275,-0.071788101,0.028574369,0.00633785,-0.004502949,0.070411775,-0.222647201,-1.016391305,-1.315382496,-2.424623506,-2.702889864,-2.335682423,-2.967448127,0.54153325,0.097891039,-13.64692426,-17.0015833,-14.03822873,-12.0828095,-13.38019002,-11.73180975,-7.62633047,-2.725776423 -4126,R241G,0.011906495,0.002857784,-0.011041947,-0.380109442,-1.734141371,-0.076695167,0.001028804,0.022784186,0.00800015,0.010427931,-0.004712364,-0.020604779,-0.001479114,-0.137359669,-0.622859215,-1.584687182,-1.883595559,1.019141708,1.341715451,-14.65443616,-17.37099989,-13.70855297,-12.60731023,-15.52452294,-14.06079476,-7.373169421,-3.756955602 -4127,R241F,-0.024787012,0.00875149,-0.64979902,-1.764842636,-3.110670886,-0.095421585,-0.010697934,-0.03887609,0.005338975,0.094621499,-0.07711852,-0.279568405,-1.020029634,-1.696179537,-1.833505734,-2.628427753,-3.592914018,1.153898663,0.725994933,-12.43081222,-13.03544014,-10.89002439,-11.31325642,-12.6608269,-14.25451323,-6.577830233,-2.902312775 -4128,R241I,-0.013066701,0.015932973,-0.054218598,-1.668082353,-2.126474784,-0.026963214,-0.000703044,-0.025430357,-0.011482931,0.021298842,0.010567103,0.022650373,-0.131087569,-1.443025077,-1.893139628,-2.308326503,-1.944623065,0.817757974,0.718236162,-11.77907322,-14.17737931,-12.16146342,-10.18150935,-11.49224924,-10.88276477,-7.330785375,-2.235129835 -4129,R241H,0.019062724,0.001406007,-0.005179293,-1.064610456,-1.777018224,-0.112682724,0.04024897,-0.002123523,-0.014153837,-0.005228707,0.008040721,0.005682952,-0.016041537,-0.807658727,-1.321562184,-1.569975992,-1.984060455,2.893909877,2.295703138,-8.240152638,-10.43017805,-7.779297577,-7.42847184,-7.549151527,-8.0136642,-7.632182704,-2.620532368 -4130,R241K,0.046051838,0.047101974,-0.038313137,0.023925123,-1.507817216,-0.070776851,0.066664471,0.025439204,-0.005769602,0.099025827,-0.004821879,0.001653198,-0.078279471,0.111394433,-0.063544188,-1.300687691,-1.714946741,0.55664262,1.321871757,-8.889882747,-10.7338609,-8.043897263,-8.105034103,-9.154072029,-8.412549438,-7.757908788,-3.846202867 -4131,R241M,0.042108411,0.018826722,0.019520253,-1.612171243,-1.990657395,-0.101458809,0.043545872,0.04067095,-0.01877311,0.003521629,0.034131814,-0.015380142,0.054420647,-1.071644344,-2.152698141,-2.043401101,-1.937913688,2.277414835,1.555363719,-10.19033618,-11.66319719,-9.187466331,-9.575750481,-9.314722145,-11.21054475,-7.056193131,-3.401153036 -4132,R241L,-0.026596828,-0.018877137,-0.041630805,-1.436486669,-2.011470748,-0.103056131,-0.009695376,-0.043498279,-0.024099123,0.035405856,-0.07316013,0.058621803,-0.141883413,-1.25928438,-1.613688958,-2.017821038,-2.005120457,2.388186356,1.595702133,-9.362577834,-10.8133187,-8.140190521,-7.71786599,-9.81294828,-10.32856567,-6.957559774,-2.046428549 -4133,R241N,-0.021572766,-0.013714809,-0.026788793,-1.112261388,-1.992377845,-0.023699373,-0.00775863,-0.035386902,-0.073720588,0.040599978,-0.068029595,0.003070147,-0.056647733,-0.704779709,-1.519743066,-1.733937938,-2.250817752,2.163906295,1.659054508,-11.32775862,-11.98449304,-11.42015608,-10.14130768,-11.41435835,-11.67847797,-5.491333458,-2.481570683 -4134,R241Q,0.054715823,0.023750611,0.035754436,-0.899547829,-1.993369224,-0.079126788,0.06004499,0.049386655,-0.013291194,0.018679955,0.028821267,0.021961574,0.049547297,-0.518770236,-1.280325421,-1.612550991,-2.374187457,1.874814006,1.556200955,-10.02741834,-10.91675191,-9.497010468,-8.860969543,-11.27398707,-9.588372688,-7.688362044,-2.649398676 -4135,R241P,0.009473081,-1.469748114,-1.673374965,-1.788275454,-2.096688393,-0.021387608,0.027353097,-0.008406935,-0.046283871,-1.406229471,-1.533266757,-1.802433787,-1.544316142,-1.778066677,-1.798484231,-1.893245576,-2.30013121,0.130367061,-0.850212244,-15.55998061,-16.71843114,-14.86606956,-14.96729513,-16.06903962,-15.1790676,-9.755191922,-6.295671412 -4136,R241S,-0.013676264,0.008694949,-0.014958192,-0.016257056,-1.359872404,-0.078648736,-0.013136135,-0.014216393,-0.005868274,0.044816023,-0.027426125,0.003350428,-0.033266811,0.068785829,-0.10129994,-1.350225287,-1.369519521,2.500745098,2.232291073,-11.78566299,-12.28126911,-9.900953857,-11.69757943,-11.68142487,-13.3670877,-5.995591737,-1.772803482 -4137,R241T,0.030332524,0.013484789,0.015553299,-0.191382759,-1.666129269,-0.087208325,0.025909782,0.034755266,-0.015726962,0.034435557,-0.00746598,-0.000180561,0.031287158,-0.032974881,-0.349790636,-1.526665237,-1.8055933,0.830430723,1.328026579,-12.09644727,-11.97427353,-11.61953421,-12.25118679,-11.65919806,-12.97804374,-5.409067245,-0.775256693 -4138,R241W,0.04206307,-0.037484847,-1.167899334,-1.967444461,-2.702348336,-0.097878609,0.070264586,0.013861554,-0.030770887,-0.008355021,-0.066614673,-0.918142483,-1.417656185,-1.846424139,-2.088464782,-2.477642359,-2.927054312,2.348879139,1.093491084,-12.19103323,-12.44103796,-11.70186058,-10.69430461,-13.86588339,-12.25207961,-8.195255951,-4.718085304 -4139,R241V,0.014721255,0.013310777,0.00988001,-1.408587467,-2.026693096,-0.052529565,0.025116572,0.004325938,-0.033002275,0.026312063,0.00030949,0.067174668,-0.047414649,-1.244250324,-1.57292461,-2.10955175,-1.943834442,2.320028209,1.517292732,-11.73726063,-12.99162476,-11.53285156,-10.56671231,-12.88388171,-10.71123279,-6.440676297,-1.497151153 -4140,R241Y,-0.006965551,0.012177525,-0.962852965,-2.009940332,-3.117827491,-0.079916174,0.024028992,-0.037960094,0.006576927,0.053163017,-0.028807968,-0.683381029,-1.242324901,-1.772671645,-2.247209019,-2.81406433,-3.421590651,1.894122131,0.873264179,-12.27465176,-15.67427855,-12.71191299,-11.50034962,-11.00994752,-10.47677013,-7.183835805,-1.982449093 -4141,G242A,0.019968479,-0.019883982,0.003465757,-0.012514385,-0.296453177,0.034622018,0.008288929,0.031648028,-0.017195342,-0.041342648,0.001574684,-0.006063122,0.012994635,-0.044027422,0.018998653,-0.161698342,-0.431208011,1.533961424,2.270422064,-2.923130554,-3.699088242,-2.718300697,-3.153576599,-1.630787933,-3.4138993,-3.486783934,-0.834891951 -4142,G242C,-0.02794067,0.084285486,-0.071635801,0.035396777,-2.027301849,0.022479061,-0.083980921,0.028099581,0.032736981,0.030142688,0.138428283,-0.11810937,-0.025162232,0.041935738,0.028857816,-1.577884443,-2.476719254,0.58790787,1.311444705,-9.484352937,-9.436618805,-10.0337627,-10.03131647,-7.976207397,-9.943859314,-6.216412279,-1.000176927 -4143,G242E,0.047079483,-0.709178191,-1.947909869,-2.019097557,-3.223613025,-0.044543503,0.033582851,0.060576115,-0.038405924,-0.319931994,-1.098424388,-2.188868262,-1.706951475,-2.135023243,-1.903171871,-2.858592861,-3.588633189,0.593214537,-0.359537109,-11.97965085,-12.08102246,-10.13479467,-12.97929693,-10.68766671,-14.01547349,-9.36387064,-7.989895929 -4144,G242D,0.059654078,-0.927510732,-2.293886831,-2.263309766,-2.669919713,-0.01547825,0.069329991,0.049978165,0.037529244,-0.576326422,-1.278695042,-2.359726994,-2.228046668,-2.430820712,-2.095798819,-2.552330339,-2.787509087,0.331494165,-0.517508637,-10.07526339,-10.37248876,-9.819390106,-10.5269671,-8.807720558,-10.84975043,-5.765351645,-2.240308421 -4145,G242F,0.012458879,-1.662095826,-2.077613387,-2.256600975,-3.052286547,-0.057445046,0.027524911,-0.002607153,-0.068197081,-1.765041902,-1.55914975,-1.98318513,-2.172041643,-2.531400102,-1.981801847,-2.652909729,-3.451663365,-0.17197271,-1.082036255,-17.54349386,-15.40505966,-19.95554143,-18.2729686,-16.59588768,-17.48801191,-9.36387064,-7.989895929 -4146,G242I,0.039835043,-1.480163282,-2.669445131,-2.459357094,-2.832493647,0.027044502,0.033520744,0.046149342,-0.041395976,-1.244015161,-1.716311403,-2.416400899,-2.922489362,-2.487494617,-2.431219571,-2.307974248,-3.357013045,0.446799178,-0.749588788,-13.79686815,-12.73304449,-16.51981239,-14.14848635,-11.27984464,-14.30315286,-6.692846389,-2.969460901 -4147,G242H,-0.017238353,-0.022541111,-1.209522301,-2.04438682,-3.045159625,0.071388884,-0.036087599,0.001610893,0.038690591,0.044383127,-0.089465348,-1.011909281,-1.40713532,-1.912306772,-2.176466868,-2.63587639,-3.45444286,2.268281116,0.979162219,-11.34400576,-7.722735443,-11.96367124,-11.89716888,-9.193399857,-15.94305336,-5.206718582,1.035830707 -4148,G242K,-0.0000727,-1.937239742,-2.355990324,-2.534977912,-2.908114465,-0.018763095,-0.00621108,0.006065645,-0.043322491,-2.401221076,-1.473258408,-2.193395572,-2.518585075,-1.963459294,-3.10649653,-2.385998917,-3.430230012,-0.589308439,-1.164380424,-13.38763742,-12.3456992,-12.36858765,-13.93809781,-11.90908575,-16.3767167,-9.36387064,-7.989895929 -4149,G242M,-0.030341482,0.021814165,-1.240125203,-2.645899357,-3.01903591,0.006358097,-0.027297543,-0.033385421,-0.037822109,0.056765168,-0.013136839,-0.818520868,-1.661729537,-2.328947279,-2.962851435,-2.450456906,-3.587614913,0.769575469,0.162863884,-13.66170345,-13.12341527,-14.96220249,-14.58538364,-11.81028213,-13.82723373,-6.794746247,-2.626397331 -4150,G242L,0.004138069,-1.805745588,-2.258671369,-1.960537702,-3.304678282,0.031867696,-0.01505875,0.023334888,-0.047946347,-2.027219075,-1.584272101,-2.421453562,-2.095889175,-2.015426025,-1.905649379,-3.011996916,-3.597359647,-0.530072135,-1.145908084,-13.42630293,-11.1719268,-14.45627978,-15.15536514,-12.61768926,-13.73025369,-5.95038209,-2.416103581 -4151,G242N,0.050680058,0.058064496,0.023493532,-1.443334135,-2.883240142,-0.006618384,0.044711376,0.056648739,-0.105273165,0.063219147,0.052909844,0.171108183,-0.124121119,-1.152231585,-1.734436684,-2.477861195,-3.288619088,0.43506133,0.711720285,-5.451982681,-3.891725761,-5.487293739,-5.437034233,-3.483097656,-8.960762016,-3.147978094,2.092658447 -4152,G242Q,-0.038406096,-0.065172092,-1.555720351,-2.43797803,-2.811114583,0.049681324,-0.02452216,-0.052290032,0.026989932,0.014902721,-0.145246905,-1.374192126,-1.737248575,-2.37470477,-2.501251289,-2.496214397,-3.126014768,0.496666542,0.048585479,-12.96810395,-11.38536564,-11.69882542,-14.47567482,-10.96360384,-16.31705,-8.042506457,-4.853139761 -4153,G242P,0.019894371,-1.626761953,-2.277715666,-2.333921743,-2.566195875,0.012166202,-0.012963742,0.052752484,-0.03788816,-1.629393219,-1.624130686,-2.178529666,-2.376901665,-2.39575142,-2.272092065,-2.517261047,-2.615130703,-0.301666811,-1.048345528,-12.46006301,-12.32502893,-12.48947481,-13.10456232,-11.23329959,-13.14794939,-9.36387064,-7.989895929 -4154,G242S,-0.002162718,0.007008101,0.019852939,0.032287125,-1.011533178,-0.046007477,-0.013968507,0.009643072,0.007749151,0.038450381,-0.024434179,0.041444194,-0.001738316,0.040137128,0.024437121,-0.590491845,-1.432574511,0.721737569,1.418405045,-3.046935623,-3.823407021,-2.267185654,-3.589347816,-2.286620132,-3.268117493,-2.974873642,-0.123412951 -4155,G242R,-0.003627604,-1.743913977,-2.060574002,-2.233552101,-2.698539214,-0.022736546,-0.027984123,0.020728915,-0.089629304,-1.873896281,-1.613931673,-2.025092719,-2.096055285,-2.12837112,-2.338733082,-2.322431415,-3.074647012,-0.466980594,-1.125870686,-15.96982515,-12.3164422,-15.9730575,-17.72762822,-13.79948146,-20.03251639,-9.356225304,-7.961305169 -4156,G242T,-0.006713652,0.003082571,-1.225077446,-2.064022705,-2.879462548,0.072060647,-0.028665889,0.015238585,-0.058683578,0.040678883,-0.034513742,-0.795455563,-1.654699329,-2.052185858,-2.075859551,-2.474725481,-3.284199615,1.919868042,0.780659948,-7.478744797,-8.172118492,-6.902006027,-8.721787788,-5.087203094,-8.510608582,-5.710115313,-1.763918178 -4157,G242W,-0.011548182,-1.703825526,-2.127367915,-2.745488706,-2.934636866,0.058779047,-0.00737699,-0.015719374,-0.087303071,-1.784437828,-1.623213223,-2.178672315,-2.076063515,-2.550796029,-2.940181382,-2.973335651,-2.89593808,-0.326238774,-1.113085917,-16.00344075,-13.87773368,-16.07976348,-17.68528578,-14.60468019,-17.76974064,-9.36387064,-7.989895929 -4158,G242V,-0.033050471,-0.531326134,-1.790027489,-2.381803028,-2.889362236,0.028155857,-0.034184946,-0.031915996,0.028551123,-0.238196562,-0.824455705,-1.776832266,-1.803222711,-2.200108502,-2.563497553,-2.92367812,-2.855046352,1.134900611,0.004831487,-10.58243262,-10.00744237,-13.78068269,-10.74166592,-7.499488815,-10.88288329,-6.090385576,-2.019193853 -4159,G242Y,0.093745054,-1.674249322,-1.911044105,-2.411758032,-2.983864589,0.016863656,0.091193137,0.09629697,-0.058390713,-1.866383529,-1.482115114,-1.959588021,-1.862500188,-2.507802994,-2.315713069,-2.629312621,-3.338416556,-0.269042314,-1.097512604,-17.6006721,-14.7011026,-20.80925384,-17.02177246,-15.33553066,-20.13570096,-8.090244589,-4.853139804 -4160,I243A,0.065622234,0.07417012,0.089976342,-1.181735294,-2.057418444,0.014191134,0.043586543,0.087657925,-0.024912074,0.092165237,0.056175002,0.073365698,0.106586986,-0.651611478,-1.71185911,-2.012649241,-2.102187646,1.809946653,1.414766885,-10.30169086,-12.31451107,-8.785876099,-8.837180855,-11.41756712,-10.15331918,-5.483169159,-1.937972041 -4161,I243C,0.065508991,0.088783178,0.058582678,0.009597641,-1.059116701,0.017647977,0.053221397,0.077796584,-0.044899344,0.127506207,0.050060149,0.052110981,0.065054375,-0.008715603,0.027910885,-0.758953125,-1.359280277,1.043947005,1.470494542,-10.66389914,-12.30887901,-9.40971521,-11.06627554,-11.34629003,-9.188335899,-7.057477235,-3.902990463 -4162,I243E,0.010596776,0.055199009,0.004737124,-1.500954022,-2.438004616,-0.038913062,-0.022565222,0.043758774,-0.022663985,0.102230199,0.008167819,0.086767973,-0.077293726,-1.44625532,-1.555652723,-2.195835317,-2.680173915,1.03330992,0.742310715,-11.11002178,-12.71423007,-9.433608528,-11.78301006,-11.96503222,-9.654228027,-5.128931042,1.067602656 -4163,I243D,0.037478649,0.069273607,-0.690027728,-2.004955286,-2.565342048,-0.036323824,0.015904704,0.059052594,-0.071348492,0.039426436,0.099120777,-0.372756662,-1.007298793,-1.978679383,-2.031231189,-2.126199389,-3.004484706,1.411111592,0.708082913,-8.771093701,-9.641717232,-6.780879417,-9.736708427,-11.33588622,-6.360277214,-4.984538349,2.980735268 -4164,I243G,0.043449277,-0.656726809,-2.061737318,-2.372592318,-2.751308632,-0.011737646,0.026099373,0.060799181,-0.00490937,-0.354050959,-0.959402658,-2.16004255,-1.963432086,-2.206777082,-2.538407554,-2.813689576,-2.688927688,0.660499126,-0.347066547,-13.17959777,-15.45428394,-11.97690398,-12.86204861,-14.14493487,-11.45981747,-6.777238499,-2.501576655 -4165,I243F,-0.036396198,0.020919039,0.023807677,-0.158977303,-1.528532822,-0.073707766,-0.048921208,-0.023871188,-0.062669146,0.069878272,-0.028040195,0.023750298,0.023865055,-0.012670095,-0.30528451,-1.542622803,-1.514442841,0.781765616,1.323995183,-7.970815227,-10.08807221,-7.357606613,-8.548718834,-7.072960983,-6.786717491,-7.051944519,-4.36075388 -4166,I243H,0.00770152,0.032771047,-0.692595712,-1.755779025,-2.491182057,-0.016622801,-0.011706175,0.027109215,-0.04959073,0.044588067,0.020954026,-0.397888867,-0.987302557,-1.784609638,-1.726948411,-2.171011734,-2.81135238,1.170761136,0.715058381,-10.7512672,-11.56876872,-9.46884922,-12.56076768,-10.41082461,-9.747125755,-6.733645504,-1.983395441 -4167,I243K,-0.035572865,-1.452557784,-1.896455542,-2.493893114,-2.704794874,0.01113251,-0.043800903,-0.027344826,-0.105278407,-1.670686839,-1.234428728,-1.980056247,-1.812854837,-2.40700202,-2.580784208,-2.457612014,-2.951977733,-0.10823725,-1.065455235,-11.83710142,-14.19486761,-9.431663864,-11.97578048,-12.03066524,-11.55252988,-8.947197448,-7.524563701 -4168,I243M,0.04291108,0.037125802,0.069005851,0.02935891,-1.109995239,-0.028641449,0.05057684,0.03524532,-0.066469587,0.096239836,-0.021988233,0.063475824,0.074535878,0.101519386,-0.042801567,-1.174646018,-1.04534446,0.700773883,1.341121153,-8.295955888,-8.799234001,-7.841176262,-8.811511292,-8.9476586,-7.080199287,-8.880794452,-7.311895812 -4169,I243L,0.040114779,0.068840548,0.073224285,0.013945488,-0.076638868,0.013247662,0.028258304,0.051971254,-0.018048194,0.085429043,0.052252052,0.038278415,0.108170155,0.004113932,0.023777044,-0.056668894,-0.096608842,1.325898485,2.473707264,-4.608048601,-4.217863388,-4.570081276,-5.371840294,-4.816556389,-4.063901657,-5.270947343,-2.301809001 -4170,I243N,0.021870122,-0.004364141,-0.761701438,-2.137489569,-2.781042042,-0.002352431,-0.001547004,0.045287247,-0.031857315,0.022453622,-0.031181904,-0.438886014,-1.084516862,-2.125107035,-2.149872103,-2.652838283,-2.9092458,1.479856947,0.674675713,-7.169994659,-8.375653969,-6.240229622,-7.660734131,-7.475560852,-6.097794724,-4.513948793,-0.91189504 -4171,I243Q,-0.045078029,0.012335844,-0.0154672,-1.780074959,-2.610417763,0.007899545,-0.095661887,0.005505829,-0.037903951,0.036352231,-0.011680543,-0.004829987,-0.026104413,-1.724585425,-1.835564493,-2.076225414,-3.144610112,0.690522931,0.687069492,-11.80638272,-13.30653812,-10.25005946,-13.09220164,-10.78431976,-11.59879461,-8.086470935,-4.974837553 -4172,I243P,0.051477898,-1.593185545,-2.230320158,-2.301918801,-2.686522533,-0.00279647,0.026213259,0.076742537,-0.081950753,-1.655464765,-1.530906325,-2.447284261,-2.013356054,-2.12950254,-2.474335062,-2.674962555,-2.69808251,-0.087591647,-1.061373189,-13.5438329,-15.35888942,-13.05350346,-13.50056636,-13.96186192,-11.84434332,-8.947197448,-7.524563701 -4173,I243S,0.013539914,0.040877079,-0.936215331,-2.158444828,-2.777826528,-0.002765089,0.000157094,0.026922734,-0.06904674,0.057538695,0.024215463,-0.570250618,-1.302180043,-1.950230848,-2.366658807,-2.347628328,-3.208024727,1.702379962,0.766866456,-10.75295923,-12.50100073,-10.43171204,-10.67010694,-11.55284229,-8.609134125,-6.919913988,-2.979832094 -4174,I243R,0.013166849,-1.329316832,-1.985501269,-2.492894051,-3.511946026,-0.02233366,-0.015959624,0.042293322,-0.070903566,-1.240909277,-1.417724387,-1.956651862,-2.014350676,-2.53486531,-2.450922792,-2.886505299,-4.137386752,0.660023241,-0.715719507,-13.54566162,-14.67477096,-12.78254327,-13.92391099,-13.24186958,-13.10521329,-8.947197448,-7.524563701 -4175,I243T,0.034700401,0.0433872,0.07718544,-1.090716959,-1.727102205,-0.045848094,0.012469257,0.056931545,0.004101212,0.058865654,0.027908746,0.050870783,0.103500097,-0.701543817,-1.479890101,-1.779212043,-1.674992367,2.026990105,1.563571589,-9.095602695,-10.35768358,-7.693920609,-8.577382683,-10.36173849,-8.487288109,-6.122047185,-3.114581649 -4176,I243W,0.0360212,0.044776381,0.052939125,-0.902338249,-1.790956755,-0.045507098,0.008129009,0.063913391,0.001336292,0.065473542,0.024079219,-0.004810122,0.110688372,-0.646135766,-1.158540731,-1.754451893,-1.827461616,1.948174172,1.535148341,-11.71498308,-13.48342937,-11.42175362,-12.19147546,-11.40541675,-10.07284021,-8.947197448,-7.5245637 -4177,I243V,0.025321068,0.025203681,0.068278409,-0.022591264,-0.035947545,0.005088205,0.001635023,0.049007112,-0.032580653,0.04322553,0.007181831,0.036820618,0.099736199,-0.029657972,-0.015524556,-0.058302447,-0.013592642,1.233653721,2.383984478,-3.749243263,-4.151168633,-3.834317978,-2.955548965,-4.195809998,-3.609370743,-4.628277254,-1.73228398 -4178,I243Y,0.030213179,0.027129394,0.026286508,-0.07660408,-1.383647832,-0.098154914,0.024000491,0.036425867,0.054430975,0.061747537,-0.007488749,-0.039668065,0.09224108,-0.06284801,-0.090360149,-1.478505304,-1.288790359,0.666937432,1.320370207,-9.338147717,-11.66803503,-8.665228439,-10.23079481,-8.291348976,-7.835331329,-7.536271034,-4.698523722 -4179,I244A,-0.007152378,0.015890875,-0.021977888,0.020203052,-1.073623609,-0.007154087,0.005187907,-0.019492663,-0.043698343,0.051190389,-0.019408639,-0.00179777,-0.042158006,0.032808696,0.007597408,-0.654165896,-1.493081322,0.785748695,1.421344429,-5.330614505,-7.073929871,-5.457711052,-5.636134682,-3.745444527,-4.739852394,-3.153290669,-0.405714426 -4180,I244C,0.022641424,0.001546656,-0.031098224,0.040619194,-0.823006157,-0.0489674,0.020656512,0.024626335,0.077993903,0.036028943,-0.032935631,-0.001441337,-0.060755111,0.023903922,0.057334465,-0.290490035,-1.355522279,1.170555458,1.81393943,-8.82075938,-11.21163763,-9.454452446,-9.642571991,-7.241193375,-6.553941452,-5.659179802,-2.59414956 -4181,I244E,0.016434434,-0.644728313,-1.918909803,-2.48572108,-2.880303607,-0.024096356,0.011015864,0.021853004,0.016390416,-0.260257373,-1.029199253,-1.733483583,-2.104336022,-2.689170486,-2.282271674,-2.515447804,-3.245159409,1.15172731,0.016717607,-11.62730782,-13.93446906,-12.45063636,-11.50719923,-10.28237143,-9.961863022,-9.082265126,-9.173498397 -4182,I244D,0.077135049,-1.534247897,-2.518009859,-2.175049168,-2.745722954,-0.022702572,0.103359905,0.050910193,-0.050150074,-1.574612847,-1.493882946,-2.160878571,-2.875141146,-2.08853675,-2.261561586,-2.215844064,-3.275601844,-0.025506762,-0.996070606,-11.58581791,-14.28138889,-12.26633394,-11.42788671,-9.989764038,-9.963715965,-9.109593716,-9.367374332 -4183,I244G,0.001152148,-0.062283497,-1.301528742,-2.068622095,-2.384993055,-0.023535357,0.008713866,-0.00640957,0.027617265,-0.019775527,-0.104791467,-1.073995967,-1.529061516,-2.104316487,-2.032927702,-2.263808484,-2.506177625,3.218408153,1.747094101,-10.79211838,-13.30399988,-10.74251078,-10.96663734,-9.227958145,-9.719485764,-6.216840116,-2.7222463 -4184,I244F,0.043547304,-0.004534079,-0.029161945,-1.268914626,-2.43572497,-0.034944849,0.077751729,0.009342878,0.035241372,-0.008531188,-0.000536969,0.016878848,-0.075202738,-1.003646614,-1.534182637,-1.998715953,-2.872733986,2.22480963,1.557580615,-9.703467154,-12.4180079,-10.29370527,-10.69897815,-7.372225693,-7.734418762,-6.068192792,-4.065093317 -4185,I244H,0.003753042,-0.786678376,-2.636017682,-2.244601985,-2.599593889,-0.008844934,0.017166831,-0.009660747,0.037324323,-0.438617871,-1.134738881,-2.200974854,-3.071060509,-2.07748051,-2.411723459,-2.681909079,-2.517278698,0.601104304,-0.412550146,-11.08668098,-13.17637355,-12.00241818,-12.18982189,-8.961529694,-9.103261604,-7.911028932,-6.927088599 -4186,I244K,-0.02316096,-1.545860862,-2.416000933,-2.001706491,-3.095259022,-0.108309821,-0.03658313,-0.00973879,-0.013396587,-1.506953515,-1.584768208,-2.519187972,-2.312813894,-1.872814882,-2.130598099,-2.699092201,-3.491425842,-0.025066021,-0.966104585,-11.21553403,-13.69153101,-11.85655478,-11.18525734,-9.484025879,-9.860301125,-9.109593716,-9.367374332 -4187,I244M,0.004732867,-0.017520999,-0.022535777,0.047888536,-0.239541728,-0.052784062,0.029457992,-0.019992259,0.094683491,-0.028973775,-0.006068223,-0.030251113,-0.01482044,0.054231879,0.041545192,-0.170257648,-0.308825807,1.47996285,2.272949046,-6.47940029,-6.870320038,-7.225805115,-7.710339478,-5.894047714,-4.696489105,-5.465041645,-3.015045014 -4188,I244L,0.046837547,0.030961463,0.011056081,0.049687138,-0.235075165,-0.025678896,0.051939384,0.04173571,0.054941923,0.031084578,0.030838348,0.02171899,0.000393171,0.037747623,0.061626652,-0.120817384,-0.349332945,1.46857067,2.446598589,-5.530726764,-7.048837624,-6.882675598,-6.972667191,-3.573000587,-3.17645282,-4.857129451,-2.448799601 -4189,I244N,-0.001366747,0.008084051,-1.284721924,-2.24855002,-3.333238167,-0.030392407,0.024332696,-0.027066189,0.025841241,0.069043293,-0.052875192,-0.950140023,-1.619303825,-2.318007373,-2.179092666,-2.922435941,-3.744040392,0.5694429,0.11314909,-9.195430228,-11.51191214,-11.37822757,-8.754122459,-6.714432663,-7.618456306,-6.070973019,-5.441105982 -4190,I244Q,0.050085889,-0.592769631,-2.010695533,-2.59640109,-3.141498615,0.013850338,0.054863657,0.04530812,0.030508899,-0.268009794,-0.917529467,-2.109548023,-1.911843042,-2.338236197,-2.854565983,-2.766573507,-3.516423722,0.726671798,-0.260870819,-11.45010705,-14.0516451,-12.35722339,-11.63461196,-9.485426033,-9.721628761,-9.109593716,-9.367374332 -4191,I244P,-0.007786819,-1.824367883,-2.21946468,-2.481261497,-3.225329025,-0.007815304,0.011786804,-0.027360441,-0.03921509,-1.744248743,-1.904487023,-2.455453204,-1.983476155,-2.383111383,-2.57941161,-2.811448692,-3.639209358,-0.58165319,-1.094030348,-12.10081551,-14.12447701,-12.96553632,-12.38819677,-10.63211231,-10.39375515,-8.830916916,-8.120035386 -4192,I244S,0.035562922,0.007599284,0.00403651,-1.519546852,-2.244336833,-0.042046263,0.054440756,0.016685088,-0.01085512,-0.00900249,0.024201058,0.023761288,-0.015688268,-0.950795761,-2.088297943,-2.14600331,-2.342670355,2.02707648,1.41150632,-7.911682765,-9.834381706,-8.772996407,-8.505118156,-6.207642365,-6.238275192,-6.130250406,-2.296846334 -4193,I244R,-0.000808594,-1.702959251,-1.995138008,-2.350243011,-2.637885627,-0.033758369,-0.00348903,0.001871842,-0.059515648,-1.771234794,-1.634683708,-2.156585675,-1.83369034,-2.31832706,-2.382158962,-2.512581163,-2.763190091,-0.141702847,-1.078846315,-11.99298197,-14.94713016,-13.10632375,-12.14341821,-9.883784149,-9.884253601,-9.109593716,-9.367374332 -4194,I244T,0.029200261,0.051152921,0.003171942,0.091515372,-1.26337091,-0.051223919,0.035183048,0.023217474,0.009238788,0.07896627,0.023339572,0.014300073,-0.00795619,0.094733094,0.08829765,-0.76383774,-1.76290408,0.595264548,1.367876311,-4.364479523,-5.54005381,-4.788003777,-4.612177811,-2.760399467,-4.121762749,-3.85947255,-2.191479522 -4195,I244W,0.007254213,-1.489133537,-2.026848198,-2.38640492,-3.007136282,-0.022107403,0.024142414,-0.009633989,0.020651806,-1.489120738,-1.489146336,-2.075386462,-1.978309933,-2.730043369,-2.042766471,-2.857350683,-3.156921881,-0.208342071,-0.928859125,-11.85298989,-15.12816426,-13.09668448,-12.31070995,-9.820599876,-8.908790886,-6.770993869,-4.318748962 -4196,I244V,0.063351737,0.047562498,0.007922957,0.07763918,0.041399423,-0.026606962,0.062326458,0.064377015,0.068438873,0.035430723,0.059694273,0.02104629,-0.005200376,0.055550563,0.099727796,0.026473977,0.056324869,1.358406575,2.976588336,0.069446844,-0.20368866,0.328452095,0.095780403,0.200872581,-0.074182198,-0.296350994,0.236958621 -4197,I244Y,-0.017399841,-0.059205373,-1.313679444,-1.920772211,-3.36554001,-0.008005634,-0.027993075,-0.006806606,0.01803603,0.013910292,-0.132321038,-1.142467607,-1.48489128,-2.08901113,-1.752533292,-2.994469694,-3.736610326,0.689531227,0.09432728,-10.3847105,-13.83162063,-11.2075121,-10.35086505,-7.809050262,-8.724504471,-5.571866729,-4.047612026 -4198,A245C,0.026716313,0.030424905,0.007611765,0.020032078,-0.134037041,-0.023658857,0.027944385,0.02548824,0.063362729,0.020861148,0.039988662,0.000858547,0.014364983,0.032074187,0.007989969,-0.064102045,-0.203972036,1.271284413,2.378906169,-8.280635352,-8.072900391,-8.407343369,-7.777071205,-7.557236687,-9.588625107,-7.746832233,-5.583922504 -4199,A245E,0.052144564,-1.304509822,-2.063645982,-2.549644364,-2.425668012,-0.033795361,0.05629798,0.047991147,0.041503252,-1.382353775,-1.226665869,-2.180048298,-1.947243665,-2.544468712,-2.554820016,-2.640028486,-2.211307537,-0.229231438,-0.86496871,-8.865486498,-9.254937469,-8.337445999,-8.425584236,-8.869430679,-9.440034103,-7.673697889,-5.014784325 -4200,A245D,0.006957808,-1.647670435,-1.908391619,-2.555499648,-2.931523296,-0.040542363,0.01906998,-0.005154364,-0.04347807,-1.880599898,-1.414740972,-1.833196382,-1.983586855,-2.440654844,-2.670344452,-2.837244613,-3.025801978,-0.25912604,-1.101831329,-10.20247545,-10.33106832,-10.15113739,-9.822253212,-10.33091506,-10.37700326,-8.765330151,-7.222716351 -4201,A245G,0.007907824,0.000479785,0.004598097,0.002255979,-0.150042619,-0.01656004,0.004370293,0.011445355,0.015190296,-0.012942094,0.013901664,-0.017010552,0.026206746,0.016755498,-0.01224354,-0.097945206,-0.202140031,1.443962293,2.410744747,-3.663431198,-3.319562141,-2.918868446,-4.413447273,-4.360414604,-3.304863525,-3.954464621,0.433668811 -4202,A245F,-0.008573186,0.001549465,-0.524997786,-2.121180393,-2.347673839,-0.052706,0.009325418,-0.02647179,0.001853564,0.001055301,0.002043629,-0.20362736,-0.846368211,-1.762480489,-2.479880297,-2.047096499,-2.648251179,1.50475954,0.782130826,-9.570575224,-10.66743808,-10.57867436,-8.785353249,-7.523918472,-10.29749196,-7.751663793,-5.227288288 -4203,A245I,-0.007885645,0.019592134,-0.996024133,-1.908029112,-2.672161135,0.005113625,0.017004637,-0.032775927,0.005290231,0.034540483,0.004643784,-0.616882412,-1.375165853,-1.859968214,-1.95609001,-2.38149672,-2.962825549,2.12363396,0.99153588,-9.952998331,-10.73467154,-11.18321612,-8.322279922,-8.030671814,-11.49415226,-7.364562094,-5.302274699 -4204,A245H,-0.052815544,-1.645760074,-2.347924558,-2.532892944,-3.24953721,-0.063438776,-0.052630434,-0.053000654,-0.050140216,-1.587234121,-1.704286026,-2.685958641,-2.009890474,-2.448319063,-2.617466825,-2.844908832,-3.654165588,-0.042650508,-1.026225934,-10.65694945,-10.56567274,-10.67927341,-9.526103432,-9.921352234,-12.59234542,-9.622734055,-9.90718017 -4205,A245K,0.010416909,-1.326458252,-2.434410238,-2.531332996,-2.708386639,-0.019237367,0.036953066,-0.016119248,-0.085349462,-1.299094616,-1.353821887,-2.175970386,-2.69285009,-2.239360804,-2.823305187,-2.334920578,-3.081852699,0.351892091,-0.814459134,-10.57110859,-10.47136937,-10.54830146,-9.505665047,-10.1310688,-12.19913829,-9.622734055,-9.907180414 -4206,A245M,-0.006193753,0.008081959,0.00342815,-0.769124127,-1.93600713,-0.032434364,-0.012203189,-0.000184316,0.083192423,0.010794394,0.005369523,0.005409625,0.001446675,-0.257211856,-1.281036397,-2.178846432,-1.693167828,1.453140967,1.311852424,-9.470419118,-10.19009364,-10.33469344,-9.174012428,-8.288693047,-9.364603035,-7.935316947,-5.63266955 -4207,A245L,0.001907938,-0.021573193,-0.017939827,-1.660930373,-2.375076616,-0.057112204,0.012932292,-0.009116417,0.018198117,-0.031991857,-0.011154529,0.00219129,-0.038070943,-1.403621809,-1.918238937,-2.285301763,-2.464851468,0.694033511,0.711950767,-9.370869312,-9.577374748,-10.22538933,-8.326599075,-7.695923546,-11.02905986,-6.834354034,-4.17936011 -4208,A245N,-0.020302232,-0.669554619,-1.508535359,-2.305665431,-2.405268093,-0.029796604,-0.02384896,-0.016755503,-0.002361808,-0.395093203,-0.944016034,-1.485848793,-1.531221925,-2.590631896,-2.020698965,-2.686191669,-2.124344517,1.667907347,0.21838492,-10.10502652,-10.42772224,-10.03907861,-9.575649025,-9.721446938,-10.76123576,-9.622734055,-9.907180409 -4209,A245Q,-0.091997266,-0.901689009,-1.755091111,-2.630165118,-2.807218762,0.005447181,-0.045806056,-0.138188475,-0.014745194,-0.494018507,-1.30935951,-1.749090227,-1.761091994,-2.2896019,-2.970728336,-2.385161674,-3.229275849,1.731964813,0.156113878,-10.65259162,-10.80267835,-10.3892758,-9.821191689,-10.4011254,-11.84868687,-9.622734055,-9.907180968 -4210,A245P,-0.016626553,-1.62681056,-2.018825647,-2.308049668,-3.009359524,-0.010792111,-0.01534006,-0.017913046,-0.035187772,-1.653999993,-1.599621126,-1.998706941,-2.038944352,-2.208225395,-2.407873941,-2.780906423,-3.237812625,-0.553613789,-1.06572681,-10.07812543,-9.784262878,-10.37555206,-9.396767159,-10.04391891,-10.79012617,-9.622734055,-9.907181415 -4211,A245S,-0.000174099,0.006818567,-0.027245197,-0.019631671,-0.090878592,-0.033718448,-0.011889284,0.011541087,0.017490732,-0.002357031,0.015994164,-0.030154687,-0.024335707,-0.009979022,-0.02928432,-0.080911116,-0.100846068,1.343808419,2.373334145,-3.57832469,-3.95941568,-3.827583054,-3.620427284,-2.245999161,-4.238198273,-4.808467641,-3.878724474 -4212,A245R,-0.009630441,-1.585077411,-2.176317519,-2.223843198,-2.617993368,-0.055968687,-0.008950268,-0.010310614,-0.057285423,-1.738799616,-1.431355205,-2.138554131,-2.214080907,-2.063641851,-2.384044545,-2.501624305,-2.734362431,-0.414915417,-1.090991343,-10.03551169,-9.93696907,-9.839323547,-9.070546211,-9.57984903,-11.75087059,-8.600917371,-7.222716349 -4213,A245T,0.01883738,-0.000910474,0.003203478,-0.183266933,-1.716790487,-0.007667064,0.06434682,-0.026672061,0.028130814,-0.014890665,0.013069717,-0.020718875,0.027125831,0.016725632,-0.383259498,-1.509724561,-1.923856412,0.638492736,1.316549434,-7.125350983,-7.052668716,-7.42058194,-7.048399483,-6.414050858,-7.691053917,-7.576814111,-6.320433206 -4214,A245W,0.008167727,-0.127276629,-1.601351016,-1.800333764,-2.025842414,0.043850062,0.065934498,-0.049599045,0.004910967,-0.031736615,-0.222816643,-1.773913811,-1.42878822,-1.837304229,-1.763363299,-1.932864003,-2.118820824,1.092962418,0.032650624,-11.59341184,-11.56808339,-12.15293452,-10.82190912,-10.56905411,-12.85507806,-9.622734055,-9.907181365 -4215,A245V,-0.043080262,0.006312356,-0.010974676,-1.119378317,-1.857539899,-0.01964983,-0.02156866,-0.064591863,0.000698814,0.028725379,-0.016100668,-0.00397934,-0.017970011,-0.497066363,-1.741690271,-1.997032187,-1.71804761,1.637455191,1.376704802,-7.380883524,-8.287683456,-8.603614182,-6.01974408,-6.131548538,-7.861827362,-6.582933861,-3.095872316 -4216,A245Y,0.006988666,-0.307583865,-1.743294908,-2.095962743,-2.698135226,-0.013377302,0.035598535,-0.021621203,0.017926763,-0.144636452,-0.470531277,-1.626577723,-1.860012092,-2.070179383,-2.121746103,-2.387587906,-3.008682546,3.279747216,1.584531584,-11.79245325,-12.34916969,-12.65904759,-10.63697308,-10.02999888,-13.28707699,-9.622734055,-9.907181839 -4217,A246C,-0.038855122,-0.013791643,-0.032680972,-0.033651374,-0.037628876,0.004257053,-0.026815771,-0.050894473,0.02294918,0.040636645,-0.06821993,-0.011661866,-0.053700078,-0.020833962,-0.046468785,-0.006976392,-0.06828136,1.364752052,2.591121225,-7.511261246,-7.465646149,-7.759582603,-7.488099564,-7.084003372,-7.758974541,-8.542404704,-6.401769387 -4218,A246E,0.027042979,-0.008681236,-0.01446366,-0.637217003,-1.756558449,0.024283676,0.038845352,0.015240605,0.011614874,-0.033132497,0.015770025,-0.053790055,0.024862735,-0.168480547,-1.105953458,-1.798598765,-1.714518133,1.15621781,1.336015072,-7.798163943,-7.294775871,-8.26490078,-8.068260445,-7.711608086,-7.651274536,-8.549402723,-6.433542075 -4219,A246D,-0.026338631,0.003044556,-0.670025332,-1.852806277,-2.60408801,-0.015015526,0.006390761,-0.059068023,-0.041070981,0.018031512,-0.0119424,-0.074032951,-1.266017712,-1.64812323,-2.057489323,-2.298444834,-2.909731185,0.68114755,0.692675331,-8.166625002,-7.620525368,-8.423446236,-8.542701225,-7.839656357,-8.406795822,-8.549402723,-6.433542077 -4220,A246G,-0.004841436,-0.003428353,0.003540692,0.001633932,-1.612438124,-0.01713011,-0.01293235,0.003249479,-0.030809296,0.018118223,-0.024974928,0.030447767,-0.023366384,0.025425526,-0.022157663,-1.280499254,-1.944376993,0.915194584,1.35749758,-7.1517617,-6.971329361,-6.72309465,-7.250945602,-7.153478462,-7.659960426,-8.521964203,-6.272064761 -4221,A246F,0.012082878,-0.014821313,0.002246737,0.01790357,-0.031573143,0.001372596,0.013570139,0.010595617,-0.047333824,-0.016652865,-0.012989761,-0.00287935,0.007372824,-0.016472335,0.052279475,-0.06258537,-0.000560916,1.278958819,2.318561243,-3.017167175,-4.045339905,-2.942600014,-3.409385559,-1.573764664,-3.114745735,-3.898256282,1.319550008 -4222,A246I,0.008971914,-0.028538519,0.011916932,-0.000271221,-0.007062572,-0.046142221,0.021550465,-0.003606638,-0.012070534,-0.022564355,-0.034512682,0.019317251,0.004516612,-0.031894283,0.031351841,0.000530706,-0.01465585,1.338437336,2.636100114,-1.73596864,-1.815357307,-1.518320648,-1.34332769,-1.852369667,-2.150467888,-2.745419317,3.519719708 -4223,A246H,-0.027854181,-0.019554966,-0.029184063,-0.995243903,-2.532376938,-0.042546123,-0.007470508,-0.048237853,-0.03877869,-0.05729938,0.018189449,0.011881678,-0.070249804,-0.398031237,-1.592456568,-1.961202665,-3.103551211,1.518855483,1.361962314,-6.377951398,-6.546391518,-6.648508835,-6.45850312,-5.706768845,-6.529584671,-6.684925819,-2.979100805 -4224,A246K,-0.038384532,-0.014214087,0.003907871,-1.440481937,-2.372734848,-0.033192909,-0.061138678,-0.015630385,-0.104960275,-0.024509379,-0.003918795,0.053984575,-0.046168833,-1.197856249,-1.683107625,-2.715270187,-2.030199508,0.794432611,0.739677298,-8.139322398,-8.071451706,-8.502227097,-7.831114861,-8.036897339,-8.25492099,-8.549402723,-6.433542079 -4225,A246M,0.047774318,-0.012291977,0.019714092,0.018304669,-0.000321423,-0.027254141,0.042561798,0.052986838,0.000903551,-0.004261502,-0.020322451,0.023251293,0.01617689,-0.00874292,0.045352257,-0.008986592,0.008343746,1.27680444,2.487647338,-2.066374289,-2.77452105,-1.853202156,-1.950380653,-2.613277054,-1.140490532,-3.70162098,0.478295548 -4226,A246L,0.031707584,-0.000827179,0.016469642,0.010161872,0.050627818,-0.007193934,0.031206861,0.032208306,-0.013609819,-0.000427395,-0.001226963,0.02460412,0.008335163,-0.024648391,0.044972135,0.039115789,0.062139846,1.079231291,2.779376345,-1.397399016,-1.746725143,-1.282364517,-1.517431068,-1.470575562,-0.969898788,-2.879784822,2.257176808 -4227,A246N,0.004754704,0.030959726,0.020177209,-0.105778758,-2.121236944,-0.037931134,-0.005398292,0.014907699,0.005798157,0.103565233,-0.041645781,0.070730533,-0.030376116,0.039342185,-0.250899701,-1.532192807,-2.71028108,0.447915249,1.307913145,-8.047341643,-7.771866692,-8.177812416,-7.812602646,-7.703154793,-8.771271667,-8.064182574,-4.532428956 -4228,A246Q,-0.026453234,-0.011062802,0.00984068,-0.182989759,-1.383312283,-0.021267794,-0.048775906,-0.004130561,-0.050459198,0.019378557,-0.041504161,0.068240937,-0.048559577,-0.044861205,-0.321118313,-1.404144212,-1.362480353,0.702965446,1.326214267,-7.636120428,-7.498932892,-7.809017715,-7.318815285,-7.85588945,-7.6979468,-8.549402723,-6.433542079 -4229,A246P,0.026894836,-1.165469766,-1.84631407,-2.177271696,-2.633705164,-0.004090843,0.035144679,0.018644993,-0.010389496,-0.952730851,-1.378208681,-1.867324903,-1.825303237,-2.142468137,-2.212075255,-2.564310412,-2.703099915,3.369627491,1.306781766,-7.814902162,-7.73005352,-8.289153969,-7.849309959,-7.613791565,-7.592201797,-8.549402723,-6.433542078 -4230,A246S,0.024594903,-0.012990936,-0.007595135,-0.007267241,-0.259356936,-0.022867084,0.033337423,0.015852382,-0.03315398,-0.022794032,-0.003187839,-0.00061581,-0.01457446,-0.036680393,0.022145912,-0.132649009,-0.386064863,1.293853984,2.16233844,-6.666760973,-6.552632065,-6.04568029,-6.307207161,-6.192758682,-8.235526665,-8.549402723,-6.433542077 -4231,A246R,-0.014371983,-0.018896976,-0.91153526,-1.986564,-2.565881715,-0.029488944,-0.018339031,-0.010404934,-0.017091377,-0.013750861,-0.02404309,-0.389652513,-1.433418006,-1.978311454,-1.994816545,-2.403180184,-2.728583245,1.483306379,0.714785115,-6.652902425,-6.215869789,-6.929805939,-6.33717366,-6.699486778,-7.082175957,-6.588309029,-2.48619131 -4232,A246T,0.005329401,-0.007641452,-0.022717636,-0.020290119,-0.031454708,-0.002723244,0.001670223,0.008988579,-0.024067087,-0.031038933,0.015756029,-0.01588241,-0.029552862,-0.049581339,0.009001101,-0.03940328,-0.023506136,1.396660159,2.52588199,-4.589915735,-4.544188347,-4.431337479,-4.340063011,-4.435207191,-5.198782646,-5.979224139,-1.95932159 -4233,A246W,-0.010950095,-0.011612023,-0.007504243,-0.255592639,-1.733245878,0.058050733,0.001473744,-0.023373933,-0.063525234,0.015244191,-0.038468236,-0.012244114,-0.002764371,-0.061803127,-0.44938215,-1.614074338,-1.852417418,0.857566613,1.324697695,-6.535964009,-6.931611877,-7.341641151,-5.85939563,-5.241808075,-7.305363312,-6.226937931,-1.63400786 -4234,A246V,0.004073374,-0.001290251,0.006471136,0.001116369,-0.007765242,-0.015179049,-0.0000716,0.008218347,-0.012324765,0.004896008,-0.00747651,0.026326036,-0.013383765,-0.016132378,0.018365116,-0.011959584,-0.0035709,1.671448915,3.643209181,-0.329735574,-0.675847107,-0.356700203,0.193019386,-0.517170799,-0.291979149,-1.943826529,3.353556769 -4235,A246Y,0.011777721,-0.041966456,-0.033315704,-0.006574174,-0.043324547,-0.016667044,0.038109062,-0.014553621,-0.041116828,-0.029941182,-0.053991729,-0.060464471,-0.006166937,-0.048859438,0.035711091,-0.055728366,-0.030920728,1.353146455,2.43625927,-5.631475528,-5.947253494,-6.038446205,-6.298144043,-3.983272224,-5.890261673,-5.838548092,0.41579707 -4236,L247A,-0.029964273,0.012110365,0.010283386,-0.457632075,-2.228504933,-0.013562014,-0.048564822,-0.011363723,0.023522535,0.014653706,0.009567023,0.005380541,0.015186231,-0.079262033,-0.836002116,-1.615757501,-2.841252364,0.797052232,1.319448964,-3.909182695,-3.641802612,-4.571821503,-2.872160446,-3.819488106,-4.640640808,-4.704781987,-0.475673269 -4237,L247C,-0.014202752,-0.000923756,0.020087752,0.008728353,-1.472174002,0.005297491,-0.031975476,0.003569972,0.059406836,0.010142481,-0.011989993,0.011998399,0.028177104,-0.016323913,0.033780618,-1.181100569,-1.763247434,0.728286838,1.342885724,-8.094891953,-7.6694207,-9.255341255,-7.882702431,-7.594463165,-8.072532211,-6.768621735,-4.509640476 -4238,L247E,-0.043397088,-0.259243406,-1.786156976,-1.956403612,-2.477048234,-0.089353569,-0.060677058,-0.026117117,-0.056184059,0.020275037,-0.538761848,-1.306560041,-2.26575391,-1.662786604,-2.25002062,-2.129038914,-2.825057554,3.871444323,2.449355039,-11.06060649,-10.19148691,-12.20202135,-10.73286736,-10.83952029,-11.33713656,-9.155121949,-8.850971648 -4239,L247D,-0.048530439,-1.633580978,-1.669960766,-2.101646775,-2.845870413,0.034222543,-0.033974074,-0.063086804,-0.049369885,-1.866005878,-1.401156078,-1.371837206,-1.968084326,-2.074851255,-2.128442295,-2.444193552,-3.247547273,-0.38813607,-1.097039864,-11.53604135,-10.78815274,-13.05423653,-11.28852618,-10.80144897,-11.74784235,-9.155121949,-8.850971648 -4240,L247G,-0.069727836,-0.65892261,-1.950145334,-2.287564063,-2.816725355,0.003824348,-0.078692879,-0.060762793,0.012468232,-0.317410523,-1.000434697,-2.032756866,-1.867533802,-2.165895607,-2.409232518,-2.649181257,-2.984269452,1.005189251,-0.167189514,-8.614614087,-8.708124947,-9.993940224,-7.682692459,-7.120361679,-9.567951126,-6.192105387,-3.85984005 -4241,L247F,-0.097075138,-0.000980091,-0.019594489,-0.577659555,-1.800568319,0.028884324,-0.072418357,-0.121731918,-0.003169463,-0.025593461,0.023633279,-0.06706409,0.027875113,-0.117392362,-1.037926748,-1.830565103,-1.770571535,0.979980075,1.319224157,-4.509706436,-4.618375702,-6.211122528,-4.506268097,-3.579907196,-3.632858658,-4.519360438,-1.113331457 -4242,L247I,0.046092954,0.090285877,0.027773269,-0.012085928,0.045515109,-0.029093468,0.0403961,0.051789808,0.054221714,0.083458057,0.097113696,0.025004712,0.030541825,0.010950877,-0.035122732,0.072054614,0.018975603,1.006988195,2.82730381,-1.038436964,-1.283041382,-2.257757034,-0.514259315,-0.47469912,-0.662427971,-3.194412114,0.534409669 -4243,L247H,-0.05424543,-0.495412008,-1.75074287,-2.483458875,-3.004103497,0.062694606,-0.065808921,-0.042681939,0.050504607,-0.133919863,-0.856904153,-1.741498265,-1.759987474,-2.541422328,-2.425495421,-2.609734629,-3.398472364,0.89970387,-0.007239103,-11.56986987,-9.407322784,-13.42249461,-11.55109064,-11.01786635,-12.45057494,-9.155121949,-8.850971648 -4244,L247K,-0.004992575,-1.264236336,-2.289378523,-2.420034537,-2.091194156,-0.042449803,0.003431363,-0.013416513,0.025425814,-1.184069213,-1.344403458,-2.070111783,-2.508645263,-2.171065841,-2.669003232,-2.239378142,-1.94301017,0.203603678,-0.734903154,-10.94370031,-10.00024883,-12.54662573,-10.42992614,-10.02161974,-11.72008111,-9.155121949,-8.850971648 -4245,L247M,-0.050387859,0.035729344,-0.07620875,-0.037459542,0.046639438,-0.01368382,-0.006490944,-0.094284774,0.004611928,0.095794103,-0.024335416,0.019646185,-0.172063684,0.052624749,-0.127543833,0.102880002,-0.009601126,1.130958758,2.836043409,-2.402793707,-2.565386604,-2.479818283,-2.468709793,-2.045446762,-2.454607094,-3.980924785,-2.098778888 -4246,L247N,-0.086416069,-1.302444277,-1.990281135,-1.750755804,-2.593126764,0.022387656,-0.114006804,-0.058825333,0.08261434,-1.130823701,-1.474064852,-2.016866271,-1.963695998,-2.117820329,-1.383691278,-2.18613263,-3.000120897,3.817360113,1.648728583,-10.81016592,-10.12227948,-11.77259896,-10.76317669,-10.23701371,-11.15576077,-9.155121949,-8.850971648 -4247,L247Q,-0.057797797,-0.062653949,-1.54141911,-2.634214766,-2.566813759,-0.074259546,-0.077856659,-0.037738935,0.061648382,0.004646267,-0.129954165,-1.316319878,-1.766518341,-2.496455182,-2.77197435,-2.263737488,-2.869890029,0.542034365,0.057957846,-10.54642649,-9.869404686,-11.37236807,-10.63517986,-9.517071548,-11.33810826,-9.145504072,-8.785018815 -4248,L247P,-0.060855755,-0.869438465,-1.753347158,-2.00454277,-2.202595062,-0.029615591,-0.061775593,-0.059935917,0.01160054,-0.599701871,-1.139175058,-1.716486904,-1.790207411,-1.957619665,-2.051465875,-2.092878756,-2.312311367,4.261369202,2.445845369,-10.70571882,-10.09790717,-11.57025111,-10.39463721,-10.38361152,-11.08218707,-9.155121949,-8.850971648 -4249,L247S,-0.001673723,-0.02605746,-1.234897092,-1.957113333,-3.157485965,-0.040440994,-0.016704232,0.013356786,0.034982656,-0.023147735,-0.028967185,-0.921627621,-1.548166562,-1.946064824,-1.968161842,-2.429350474,-3.885621456,2.200343237,0.94216039,-9.199146411,-9.134909332,-9.726421593,-8.877574448,-8.822039436,-9.434787247,-8.40637304,-6.253445107 -4250,L247R,-0.062931721,-1.528493684,-2.052890538,-1.988923589,-2.478849363,-0.034273154,-0.064490761,-0.06137268,0.011497916,-1.598710848,-1.458276519,-2.419812611,-1.685968464,-2.094797937,-1.88304924,-2.464140234,-2.493558492,-0.587671425,-1.039479026,-11.41004197,-10.68116383,-11.96905318,-11.28383128,-10.6592244,-12.45693716,-9.155121949,-8.850971648 -4251,L247T,-0.041101848,-0.01539265,-0.012122843,-0.022290192,-1.595811523,-0.015417462,-0.063913841,-0.018289855,0.048392522,0.012907749,-0.043693048,-0.018631615,-0.00561407,-0.025523502,-0.019056881,-1.177612801,-2.014010245,0.736709026,1.345276163,-5.652886406,-5.3820952,-6.685633507,-5.081616783,-5.327015518,-5.788071022,-4.711481597,-2.367119789 -4252,L247W,-0.060791867,-0.081425194,-0.031796054,-0.082409111,-1.617789559,0.012270484,-0.025115709,-0.096468025,0.056476544,-0.051137285,-0.111713103,-0.039053287,-0.024538821,0.013482848,-0.178301069,-1.409804872,-1.825774246,0.60156222,1.319371867,-10.00818463,-9.145144646,-11.9610024,-9.720297096,-9.150637779,-10.06384121,-7.764980506,-5.192655301 -4253,L247V,-0.035773035,-0.024431508,-0.01884707,-0.039030294,-0.031333964,0.005880531,-0.027881087,-0.043664983,0.019649913,-0.034952963,-0.013910053,-0.037154714,-0.000539426,-0.041088406,-0.036972181,-0.057072827,-0.0055951,1.31939238,2.426049301,-1.790576743,-0.617960495,-2.96288414,-1.630470154,-1.774779198,-1.966789726,-2.782587774,1.057655568 -4254,L247Y,-0.020940984,0.059855236,-0.200521927,-1.486413716,-2.78760903,-0.031000689,-0.005258676,-0.036623291,0.076829504,0.055886534,0.063823938,-0.088916869,-0.312126985,-1.169349259,-1.803478173,-2.351604913,-3.223613147,1.036241985,0.779264415,-8.228036693,-6.216832405,-11.59725136,-7.837054184,-7.731956291,-7.757089226,-5.00301725,-3.249191319 -4255,G248A,-0.020177845,0.0000755,-0.12603547,-1.544289191,-2.338369499,0.016345092,-0.033751002,-0.006604688,-0.053061644,-0.017471102,0.017622123,-0.051887131,-0.200183808,-1.304717014,-1.783861368,-2.182826062,-2.493912936,0.353470351,0.701986042,-6.154536302,-6.419153824,-4.604703667,-5.499897728,-8.292023308,-5.956902985,-6.069141191,0.135368199 -4256,G248C,-0.00215753,-0.061574184,-1.319188816,-2.200912921,-2.276509166,0.006703817,-0.016371437,0.012056378,-0.04089358,-0.01225679,-0.110891578,-0.982963053,-1.655414578,-2.194764287,-2.207061555,-2.408880913,-2.144137419,1.948764074,0.697703965,-8.942540143,-9.365344406,-8.414338821,-8.495728432,-10.24019026,-8.197098793,-7.109318026,-1.467607963 -4257,G248E,-0.009770056,-1.046844819,-1.760789646,-2.004282849,-2.0217645,0.05060585,0.006549049,-0.026089161,0.048645137,-0.794899326,-1.298790312,-1.736668996,-1.784910295,-1.998636839,-2.009928859,-1.937277574,-2.106251425,4.299227179,2.408867543,-7.026289513,-9.268737885,-5.599913757,-4.952293274,-8.429235756,-6.881266891,-5.778276647,2.107961711 -4258,G248D,0.004725838,-0.171754274,-1.504525038,-2.035302703,-2.467998155,-0.010500608,-0.031037426,0.040489102,0.017426856,-0.0537228,-0.289785748,-1.282500626,-1.72654945,-1.883287026,-2.187318379,-2.562290451,-2.373705859,2.755090876,1.274723937,-9.407323853,-11.04365467,-8.390716125,-7.369265121,-10.28331835,-9.949664993,-6.449675096,1.091934785 -4259,G248F,-0.003476073,-0.361823517,-1.646353083,-2.316307975,-2.962285869,0.015713349,-0.022047168,0.015095023,0.017095171,-0.100290656,-0.623356377,-1.495132831,-1.797573335,-2.706934065,-1.925681885,-2.54083945,-3.383732287,0.814595485,0.045374607,-9.414263814,-8.927387589,-7.505537628,-9.257241264,-11.8424958,-9.538656784,-4.602923946,1.829809748 -4260,G248I,0.047318026,-0.931757165,-2.112793349,-2.385775482,-2.274978116,0.040800006,0.058977422,0.03565863,0.004847666,-0.775111947,-1.088402382,-2.098222364,-2.127364334,-2.163895561,-2.607655403,-2.599860938,-1.950095293,0.901266067,-0.516491224,-7.491509612,-6.747448906,-5.267815186,-7.436018913,-8.52512384,-9.481141212,-5.105059488,0.236134019 -4261,G248H,-0.003232725,0.044930621,-0.001345667,-1.660893582,-2.811644134,0.021351475,-0.033199325,0.026733876,-0.00852285,0.035408597,0.054452644,0.025374095,-0.028065429,-0.914940555,-2.406846608,-2.189755022,-3.433533245,1.955867671,1.370507963,-8.339643365,-8.350147491,-6.931704407,-7.595115898,-10.61446922,-8.206779816,-6.165200666,0.11198201 -4262,G248K,0.00109662,-0.090977342,-1.348746062,-1.971832734,-3.092234366,0.02696065,-0.005795912,0.007989151,-0.047750344,-0.020108731,-0.161845952,-1.071937856,-1.625554267,-2.091853564,-1.851811903,-2.703910199,-3.480558532,2.200772844,0.872783103,-7.792364645,-7.951387512,-6.387075684,-7.276895622,-9.028849007,-8.317615402,-6.050458201,0.446226965 -4263,G248M,0.002086932,-0.484316157,-2.122213996,-2.314234978,-3.118625003,0.010267271,-0.020849737,0.0250236,-0.015496489,-0.178471223,-0.790161091,-2.22075503,-2.023672961,-2.462519487,-2.165950468,-2.597454868,-3.639795137,0.416306975,-0.336919988,-8.864130396,-7.796717041,-6.834719925,-9.844347313,-9.374752579,-10.47011512,-5.77731895,-0.528918247 -4264,G248L,-0.012250522,-1.214422065,-2.081868533,-2.207003723,-3.208285772,0.023227093,-0.035808458,0.011307415,-0.022138335,-0.998764955,-1.430079175,-2.189732982,-1.974004084,-2.182855513,-2.231151933,-2.954612991,-3.461958553,0.629656282,-0.610327155,-8.679496524,-7.212098877,-7.014086128,-8.26454306,-9.543995331,-11.36275922,-4.434664554,0.883761037 -4265,G248N,-0.064752308,0.012548907,-0.117776827,-1.892474152,-2.968898199,-0.016044719,-0.0799957,-0.049508916,-0.023088532,0.034147944,-0.00905013,0.050985589,-0.286539242,-1.502028029,-2.282920275,-2.482061449,-3.455734948,0.538745785,0.695854021,-9.146227632,-9.975694366,-8.560578529,-8.697232277,-9.816987198,-8.68064579,-6.183730493,0.723134443 -4266,G248Q,-0.058969575,-0.321495676,-1.573450693,-2.189131425,-2.82691411,0.054314188,-0.065598679,-0.052340471,-0.055906349,-0.07597924,-0.567012112,-1.479745588,-1.667155798,-2.08948683,-2.28877602,-2.826482202,-2.827346018,0.902334284,0.055703276,-6.154750951,-6.725149231,-5.223781334,-5.251512665,-7.356614532,-6.216696991,-5.51021716,0.625256546 -4267,G248P,-0.010249036,-1.672210874,-2.048928412,-2.372155148,-3.3193927,0.004158917,-0.029869173,0.009371101,-0.113444889,-1.74130084,-1.603120908,-2.049852537,-2.048004287,-2.188076402,-2.556233893,-2.820336423,-3.818448977,0.054915626,-1.080016205,-10.62480688,-10.61881342,-9.436379898,-9.777303024,-12.72000624,-10.57153182,-8.206136964,-2.44071098 -4268,G248S,-0.029739677,-0.016820368,-0.05410371,-1.533001036,-2.356738345,0.028331527,-0.041062452,-0.018416902,-0.037630034,-0.008555874,-0.025084861,-0.009830592,-0.098376827,-1.19416312,-1.871838951,-2.373302164,-2.340174525,0.605937558,0.720605082,-6.255957784,-5.608257904,-6.309202415,-5.85840493,-8.603635376,-4.900288292,-4.961587066,0.583989336 -4269,G248R,-0.025318399,-0.019303157,-1.213143885,-1.993918542,-2.405967508,0.015247042,-0.048178433,-0.002458364,-0.040672639,0.023404958,-0.062011271,-0.887325633,-1.538962136,-1.830684238,-2.157152845,-2.103922317,-2.708012698,3.546397689,2.23131895,-5.249103955,-4.862978706,-4.418665466,-4.491831009,-7.355614418,-5.116430176,-4.600007878,1.282242025 -4270,G248T,-0.006037866,-0.470562315,-1.965202622,-2.106564038,-3.06367362,0.04443157,-0.004611275,-0.007464457,-0.003186622,-0.150204726,-0.790919903,-2.111804399,-1.818600845,-2.126325075,-2.086803001,-2.914472969,-3.212874271,0.581349527,-0.227066699,-5.679486687,-5.52503508,-3.917802727,-5.460523705,-8.758514862,-4.73555706,-4.396135467,2.276019147 -4271,G248W,-0.046069287,-0.035351886,-1.163058568,-2.187765798,-2.515789864,0.021786253,-0.059384295,-0.032754278,-0.03269935,0.010082648,-0.080786419,-0.84814097,-1.477976165,-1.940143107,-2.435388489,-2.580228466,-2.451351261,2.084947253,0.895574998,-6.358588025,-6.466692329,-7.02859671,-5.171717918,-9.771783997,-3.35414917,-3.220909799,3.15904239 -4272,G248V,-0.03305388,-1.000011231,-2.010858701,-2.174930204,-2.830067718,0.008257405,-0.051169183,-0.014938576,0.016773695,-0.716668214,-1.283354247,-2.053618614,-1.968098787,-2.119291812,-2.230568595,-3.129288456,-2.53084698,1.154910936,-0.342541519,-7.955326802,-7.48012603,-5.503853027,-7.364989418,-10.20109015,-9.226575386,-5.722703479,0.14531326 -4273,G248Y,-0.010458871,-0.245343247,-1.530777927,-2.418984521,-2.840416149,0.036971648,-0.013147918,-0.007769823,-0.040195387,-0.020542809,-0.470143684,-1.431608396,-1.629947457,-2.041349638,-2.796619403,-2.079375006,-3.601457291,3.938846337,2.361626136,-8.750681474,-9.60867231,-6.731304779,-8.644083611,-10.9171835,-7.85216317,-3.335030562,2.147633682 -4274,P249A,0.027463187,0.018360498,-0.009839366,-0.001992438,-0.578324251,-0.040891367,0.014584032,0.040342342,0.016375635,0.01057239,0.026148605,-0.016629022,-0.003049709,-0.013484262,0.009499387,-0.298469166,-0.858179336,1.353395209,1.912290501,-3.640234224,-3.521347122,-3.187146568,-3.52513549,-3.632970192,-4.334571747,-4.398757885,-1.442033785 -4275,P249C,-0.018637671,-0.007107167,-0.032167984,0.02083007,-1.200239393,0.001129808,-0.020940726,-0.016334615,0.040035404,-0.044096707,0.029882374,-0.052514656,-0.011821311,-0.014901174,0.056561314,-1.118172977,-1.282305809,0.848274813,1.364160944,-8.763224187,-8.203470047,-9.524136284,-8.042903946,-8.417202652,-9.628408005,-7.888805541,-4.820274009 -4276,P249E,-0.052040973,0.016823026,-0.026175775,-0.018463989,-0.668956032,0.089514434,0.014668513,-0.118750459,-0.083756139,-0.021133059,0.054779111,-0.041442098,-0.010909452,-0.082001757,0.04507378,-0.453559765,-0.884352299,1.537695302,1.908538703,-6.841610875,-6.719674065,-7.006441841,-5.979129692,-6.703627357,-7.799181419,-7.323274277,-4.74577004 -4277,P249D,-0.081280526,-0.004573971,-0.031232138,0.023382084,-1.041499991,0.001952611,-0.006702164,-0.155858887,-0.030489705,-0.012988342,0.003840401,-0.024677588,-0.037786688,-0.001699355,0.048463522,-0.631867109,-1.451132873,0.588675896,1.383666835,-5.916577115,-6.411473846,-5.703488342,-5.516362419,-5.878126915,-6.073434052,-6.325639288,-3.827919897 -4278,P249G,-0.025055623,-0.01026121,0.006090111,-0.502201031,-1.611388635,0.015462711,-0.027995316,-0.02211593,0.008017338,0.001660784,-0.022183204,-0.019979331,0.032159553,-0.090174097,-0.914227964,-1.604032297,-1.618744973,0.891579346,1.330430316,-5.469152647,-5.542587402,-4.754764755,-5.218153435,-5.394146912,-6.436110733,-5.171776482,-2.114497329 -4279,P249F,-0.121307136,-0.035532408,-0.074673739,-0.742706826,-2.255329162,-0.011996355,-0.113733034,-0.128881238,-0.02676797,-0.019737361,-0.051327454,-0.034136396,-0.115211081,-0.139787633,-1.345626019,-1.962344028,-2.548314295,1.031408188,1.312043906,-9.88598922,-8.112584335,-11.98961287,-8.274796227,-9.547914917,-11.50503775,-7.348648676,-2.76525778 -4280,P249I,-0.066508207,0.020159114,-0.019073854,-0.00871615,-1.808790021,-0.007242304,-0.01368472,-0.119331694,-0.070735332,0.055606207,-0.01528798,0.005904561,-0.044052269,0.003425446,-0.020857746,-1.549376663,-2.068203378,0.550480827,1.311128903,-8.599729611,-7.877147713,-10.51220399,-6.997642593,-8.336400856,-9.275252899,-7.07764273,-3.366366943 -4281,P249H,-0.011353552,0.001005746,0.005013401,-0.02053346,-1.15544864,-0.033206857,0.02855796,-0.051265064,-0.010706569,-0.005245001,0.007256492,-0.008658557,0.018685358,-0.013801321,-0.027265598,-0.772215724,-1.538681556,0.591372646,1.365651471,-7.010845583,-7.110202538,-7.872221329,-5.825972679,-6.868502296,-7.377329071,-6.71245531,-2.309731186 -4282,P249K,-0.134751354,-0.014551572,0.016346997,0.036101923,-0.073359069,-0.017275449,-0.043922322,-0.225580385,-0.025569389,0.007055816,-0.036158959,0.043782627,-0.011088633,0.059231363,0.012972482,0.064276775,-0.210994912,1.109854876,2.925519802,-5.924984605,-6.76766021,-6.354243256,-4.666414734,-5.688364967,-6.148239861,-6.255209544,-3.582647438 -4283,P249M,-0.028820572,-0.001166206,-0.033574828,0.006654939,-0.703567053,0.051505819,0.008838243,-0.066479386,0.048516501,0.024127421,-0.026459833,-0.030609044,-0.036540611,0.017160375,-0.003850497,-0.3246274,-1.082506706,1.481063743,1.971260397,-8.64603517,-7.877293823,-10.49444165,-7.813503799,-8.217487984,-8.827448593,-7.33628834,-2.562113283 -4284,P249L,0.002286881,-0.00450836,0.007697221,-0.019641353,-1.682206154,-0.010473551,0.0086805,-0.004106739,0.005328447,-0.016382312,0.007365593,0.008445275,0.006949167,0.008294585,-0.047577291,-1.434248304,-1.930164004,0.590954057,1.317453745,-6.819934868,-5.786453125,-9.44943103,-6.202299728,-6.238078194,-6.423412262,-6.64894929,-0.572270815 -4285,P249N,-0.070778995,0.084193028,0.007902225,-0.003152983,-0.450898064,0.079249441,-0.020784653,-0.120773337,-0.06731727,0.07862057,0.089765486,-0.035063386,0.050867836,-0.034215786,0.02790982,-0.251435106,-0.650361022,1.649469467,2.212074529,-5.911778421,-6.719954491,-5.962324936,-5.390713524,-5.300014824,-6.185884331,-5.822224351,-3.371537684 -4286,P249Q,-0.057459306,0.009884568,0.019006563,-0.041142532,-0.292078371,-0.037630558,-0.037367095,-0.077551517,0.003048957,0.033240399,-0.013471264,0.014359059,0.023654067,-0.011596182,-0.070688881,-0.083055104,-0.501101637,1.530051592,2.527548925,-6.436507552,-6.810111069,-7.239905098,-5.321924835,-6.393886017,-6.416710739,-6.321260862,-4.110613224 -4287,P249S,-0.018875764,-0.000343416,-0.0325316,0.021475463,-0.658121898,-0.001453281,-0.037468645,-0.000282882,0.002959615,0.028941658,-0.02962849,0.003312151,-0.068375351,0.050335828,-0.007384902,-0.334281628,-0.981962167,1.462571921,1.986795117,-3.423505547,-3.226883018,-3.572565872,-3.289885559,-3.878697212,-3.149496071,-5.057118043,-1.987228348 -4288,P249R,0.001171349,0.02185184,-0.010215739,-0.000622254,-0.132884736,0.013331525,-0.000778977,0.003121674,0.040207357,0.02919626,0.014507419,0.004762312,-0.025193789,-0.000618172,-0.000626336,-0.05502056,-0.210748911,1.329624459,2.548542363,-5.071543938,-4.631601349,-6.766330246,-4.098231064,-5.247879601,-4.613677429,-4.777417654,-2.531559687 -4289,P249T,-0.019143774,0.037485064,0.003564467,0.002096796,-0.890274021,0.025965723,-0.013009418,-0.02527813,0.009150563,0.060638644,0.014331483,0.038105494,-0.030976561,0.005108385,-0.000914793,-0.489378733,-1.291169309,0.735541811,1.456197072,-3.722260025,-4.231165787,-3.593745796,-3.060887047,-4.142802742,-3.582698753,-4.935841054,-1.427950109 -4290,P249W,-0.008029177,-0.026755557,-0.002592061,-1.089430358,-2.598471894,-0.028480413,0.012012224,-0.028070578,0.034429982,-0.010061453,-0.043449661,-0.030627777,0.025443656,-0.505561993,-1.673298723,-2.402014038,-2.794929749,1.447972918,1.241538439,-9.832979605,-8.534593994,-11.72788525,-8.918576172,-10.34306238,-9.640780228,-7.190239254,-4.281599382 -4291,P249V,-0.005313748,-0.021505232,-0.013830489,-0.002349045,-1.348060741,-0.032854463,-0.009814656,-0.00081284,-0.000725701,-0.024327679,-0.018682784,-0.033692191,0.006031213,0.00556039,-0.010258479,-1.184433628,-1.511687853,0.836285349,1.355854429,-6.779513597,-6.013790375,-8.38602243,-5.721291893,-6.619355682,-7.157107605,-6.185071484,-2.750997947 -4292,P249Y,0.010223564,0.042372486,-0.003694421,-0.351560821,-1.716285218,0.018419991,0.087665351,-0.067218224,0.02678229,0.01095086,0.073794112,-0.013439575,0.006050733,-0.115991786,-0.587129855,-1.539066517,-1.893503918,1.044873951,1.348934099,-9.792381857,-9.198796394,-12.15349696,-7.800223038,-9.350214218,-10.45917867,-6.861348336,-1.906294941 -4293,D250A,-0.0343114,-0.056401672,-0.040072522,-0.045835838,0.018321109,-0.006250417,-0.028305554,-0.040317245,-0.030596206,-0.076374213,-0.03642913,-0.080707907,0.000562864,-0.047468311,-0.044203365,0.004781946,0.031860272,1.228595653,2.552268184,-2.258856178,-2.101019646,-2.491546013,-2.881745041,-2.150501579,-1.669468613,-2.495889857,0.232841681 -4294,D250C,-0.046761057,-0.055349554,-0.100722086,-0.057974665,0.002043014,-0.035098594,-0.044452756,-0.049069358,-0.038910045,-0.051152522,-0.059546586,-0.062710683,-0.138733488,-0.036107089,-0.07984224,0.028185679,-0.024099652,1.140851641,2.701421792,-7.200121104,-7.309413925,-7.550586182,-7.374590607,-7.196072403,-6.569942406,-7.709528849,-7.373319994 -4295,D250E,-0.053075006,-0.055272993,-0.080058388,-0.052378938,-0.040105619,-0.016392834,-0.040161527,-0.065988485,0.006548987,-0.082088534,-0.028457451,-0.137121698,-0.022995077,-0.024191754,-0.080566121,0.007461276,-0.087672513,1.258682364,2.591044681,-0.997211057,-1.201031754,-0.805085663,-1.368143982,-1.135382149,-0.476411736,-2.666249654,0.162554283 -4296,D250G,-0.035801638,-0.053691911,-0.052782131,-0.059139108,-0.01997566,-0.014804711,-0.041515416,-0.03008786,-0.012805356,-0.078792552,-0.02859127,-0.102018791,-0.00354547,-0.070084187,-0.048194029,-0.024559005,-0.015392314,1.543610422,3.106887046,-2.411519276,-1.744324532,-3.139050262,-2.984970093,-2.325815887,-1.863435608,-2.304828157,-0.335101319 -4297,D250F,-0.030430468,-0.056233376,-0.036455503,-0.062189592,0.00293398,-0.072130489,-0.026584695,-0.034276241,-0.056147806,-0.07937825,-0.033088502,-0.064401094,-0.008509911,-0.03718057,-0.087198613,-0.013438855,0.019306814,1.186638969,2.423267269,-6.130720723,-6.38076899,-6.464759575,-6.104689919,-5.954971481,-5.748413651,-6.634354269,-4.487608928 -4298,D250I,-0.04399044,-0.093715849,-0.036430529,-0.086022363,-0.144254011,-0.064806034,-0.055075545,-0.032905335,-0.073155617,-0.102504675,-0.084927023,-0.083249875,0.010388818,-0.062241495,-0.109803231,-0.11937089,-0.169137131,1.396988942,2.265181592,-5.873930118,-5.938421783,-6.307766602,-5.950092911,-5.974310822,-5.199058472,-5.4195966,-3.686752436 -4299,D250H,-0.043928928,-0.047977226,-0.059884152,-0.04110273,-0.008857985,-0.012362725,-0.041156733,-0.046701122,0.019993328,-0.103251839,0.007297388,-0.087065078,-0.032703225,-0.046636421,-0.035569038,-0.049668914,0.031952944,1.356006468,2.430711902,-3.869732083,-4.012915504,-3.81170166,-4.063011505,-4.044136673,-3.416895073,-4.741006504,-2.251801038 -4300,D250K,-0.095810235,-0.113649807,-0.100958588,-0.140326868,-0.064669503,-0.034820627,-0.123669993,-0.067950476,-0.060054723,-0.194275048,-0.033024566,-0.104793845,-0.09712333,-0.094664867,-0.185988869,-0.000765407,-0.128573598,1.412929624,2.559652055,-1.554830315,-2.136968582,-2.019162819,-1.721846512,-0.971579193,-0.924594467,-2.346451509,0.143344869 -4301,D250M,-0.038329995,-0.098137883,-0.053397893,-0.065352192,-0.003194611,-0.020398395,-0.029460264,-0.047199726,-0.074607795,-0.093323507,-0.102952258,-0.055534946,-0.05126084,-0.056578924,-0.074125459,0.020153262,-0.026542484,1.076833718,2.62284945,-5.959386055,-5.325632973,-6.393387947,-6.637708542,-5.74915921,-5.691041603,-5.443172873,-3.592246606 -4302,D250L,-0.020903816,-0.058963736,-0.057688328,-0.072366492,-0.036004745,-0.034402029,-0.02540605,-0.016401581,-0.013702978,-0.105613377,-0.012314094,-0.104887132,-0.010489523,-0.070130152,-0.074602832,-0.049979161,-0.022030329,1.259084239,2.364667216,-4.979605833,-4.731705032,-5.0964664,-5.950430603,-4.724300224,-4.395126907,-4.476080855,-2.459712917 -4303,D250N,-0.049927976,-0.083286,-0.044760057,-0.062807818,0.052589912,-0.054596294,-0.061133427,-0.038722525,0.006235116,-0.085180934,-0.081391065,-0.087821031,-0.001699082,-0.056347216,-0.06926842,0.048826363,0.056353461,1.320658561,2.821707424,-2.301750992,-2.549996925,-2.511057091,-1.920041374,-2.30113102,-2.226528549,-2.991975188,-1.109003476 -4304,D250Q,-0.035824379,-0.089563318,-0.047413536,-0.046942938,0.040564806,-0.054382627,-0.057979822,-0.013668936,-0.129113894,-0.104784688,-0.074341947,-0.095587893,0.000760822,-0.065266193,-0.028619682,0.004420312,0.0767093,1.27782736,2.666259648,-3.513322182,-3.30660878,-3.788338638,-4.176928139,-3.585806976,-2.708928375,-3.960110887,-0.883578519 -4305,D250P,-0.02270569,-0.083592432,-0.068639353,-0.061241505,-0.440746278,-0.00737404,-0.000101743,-0.045309637,-0.039762905,-0.103838301,-0.063346562,-0.080796998,-0.056481708,-0.050645237,-0.071837772,-0.233316976,-0.648175579,1.429319313,2.053585997,-1.731105373,-0.114875885,-1.185726288,-4.120892754,-2.236009415,-0.998022522,-2.230483065,2.637484111 -4306,D250S,0.008853191,-0.043927193,-0.04027554,-0.024828407,0.024758953,-0.041445044,0.014548573,0.003157809,-0.05077589,-0.089518539,0.001664154,-0.104771805,0.024220725,-0.038869789,-0.010787024,0.006534995,0.042982911,1.270488892,2.533330658,-2.582229079,-2.650827744,-2.349997009,-2.759087303,-3.32093,-1.830303337,-3.253759532,-0.623608091 -4307,D250R,-0.015164748,-0.03008887,-0.036792443,-0.04641496,0.024388551,0.002411685,-0.024712458,-0.005617037,-0.017739086,-0.069669743,0.009492003,-0.085302153,0.011717267,-0.051472339,-0.041357581,-0.00838789,0.057164991,1.367983386,2.598846434,-3.698595786,-4.152090775,-3.660687904,-4.454886467,-3.768724358,-2.456589424,-3.630464412,-1.03244067 -4308,D250T,-0.029527937,-0.058690775,-0.035571633,-0.062475662,-0.051200364,0.013103855,-0.041828111,-0.017227763,-0.040009707,-0.107268464,-0.010113085,-0.082266195,0.011122929,-0.089185316,-0.035766008,-0.028519137,-0.073881591,1.216623114,2.35890501,-2.636740903,-2.550002594,-3.203403137,-2.831852928,-2.603488106,-1.994957748,-3.102038239,-0.721311226 -4309,D250W,-0.026401358,-0.06099029,-0.075976582,-0.077202904,-0.04440584,-0.078541343,-0.040920547,-0.011882169,-0.067649198,-0.094923735,-0.027056844,-0.13170417,-0.020248993,-0.068802606,-0.085603202,-0.037807439,-0.051004241,1.323961605,2.40757037,-7.291233484,-7.460956413,-7.231095207,-7.764191444,-7.132293762,-6.867630592,-7.709528849,-7.373319994 -4310,D250V,-0.015911789,-0.032001896,-0.028484045,-0.017952408,-0.065919361,-0.043230027,-0.014436939,-0.017386638,-0.054077944,-0.054151781,-0.00985201,-0.067174119,0.01020603,-0.004999677,-0.030905139,-0.045879215,-0.085959507,1.282303215,2.399132985,-4.452135561,-4.236476799,-5.03330896,-4.692470169,-4.531948303,-3.766473572,-4.316704121,-2.130332556 -4311,D250Y,-0.045159649,-0.064886331,-0.088249186,-0.050873627,-0.045429451,-0.004258543,-0.012424769,-0.077894528,0.04466585,-0.091811513,-0.037961149,-0.098544896,-0.077953476,-0.091981992,-0.009765262,-0.044595322,-0.04626358,1.363429577,2.39221161,-5.599197983,-6.083595322,-5.67045137,-5.221831078,-5.709211487,-5.310900658,-5.351538542,-4.395535105 -4312,G251A,-0.019234852,0.003103572,-0.002983572,-0.00410856,-0.06441906,0.000396871,-0.033724718,-0.004744985,-0.003219641,0.005975378,0.000231766,0.026616266,-0.032583409,-0.002673687,-0.005543433,-0.047772782,-0.081065337,1.325552123,2.394828569,-2.538602922,-3.316718178,-2.171192513,-1.413539871,-3.356177628,-2.435386421,-4.0974475,-1.501870431 -4313,G251C,0.01353473,-0.002471768,-0.013907428,-0.039658242,-0.462420625,-0.078066599,0.025774156,0.001295303,0.026346893,0.019174262,-0.024117798,-0.004997194,-0.022817662,-0.012441082,-0.066875401,-0.220328602,-0.704512648,1.421486678,2.110328662,-6.692753555,-7.106316086,-7.138986557,-5.83233989,-7.039526688,-6.346598557,-7.649084211,-4.927063355 -4314,G251E,-0.121813674,-0.004683363,-0.068405993,-0.041845212,-0.086343213,0.006829671,-0.098050353,-0.145576994,0.033839921,0.108432399,-0.117799124,0.030235182,-0.167047167,0.076879796,-0.16057022,0.010370705,-0.183057131,1.318668048,2.949930464,-2.163243079,-2.90920723,-2.026477455,-1.164674553,-2.51436274,-2.201493416,-3.932642665,-1.42032058 -4315,G251D,-0.087248599,-0.018709867,-0.028835936,-0.036620185,-0.083212315,0.047037409,-0.086332122,-0.088165076,-0.005342829,0.022112777,-0.059532511,-0.01004389,-0.047627982,-0.006384882,-0.066855487,-0.044178484,-0.122246145,1.267287011,2.445549999,-2.23468378,-3.018454727,-1.671387627,-1.257369331,-2.804944008,-2.421263206,-3.264829464,0.348731711 -4316,G251F,-0.009961013,0.038854633,-0.081592294,0.012606684,-0.36401895,-0.003059031,-0.033889673,0.013967647,0.010837649,0.034518812,0.043190454,-0.044151426,-0.119033162,-0.016512144,0.041725512,-0.235960883,-0.492077017,1.390903398,2.046974882,-7.387342218,-7.010693413,-8.824362198,-6.647225601,-7.58615554,-6.868274338,-7.759209956,-5.077593166 -4317,G251I,-0.008367595,0.047990435,0.005569009,0.005130771,-1.282882225,0.00238011,-0.027761928,0.011026739,0.03025069,0.064485355,0.031495514,0.071406627,-0.060268609,-0.036850719,0.047112261,-0.586784433,-1.978980016,0.935186815,1.496450525,-7.182386806,-7.401642799,-8.199230522,-5.992268494,-7.523895676,-6.794896538,-8.115556633,-5.625162735 -4318,G251H,-0.049572216,0.007308858,-0.063748776,0.008159742,-0.078903094,0.006517491,-0.079185559,-0.019958873,-0.030334067,0.006191542,0.008426173,-0.005831025,-0.121666526,0.019969745,-0.003650261,-0.039841724,-0.117964464,1.192226489,2.404097592,-3.869022186,-4.491677719,-4.26505883,-3.320923943,-4.098956749,-3.16849369,-3.953649888,-1.702497528 -4319,G251K,0.0472242,0.120576488,0.030751838,0.091126554,0.085538885,-0.095377082,0.037755677,0.056692722,0.0045887,0.197122081,0.044030895,0.043114615,0.01838906,0.127780917,0.054472191,0.030022624,0.141055145,1.215730156,2.850969187,-2.511589021,-3.02040847,-2.835493446,-2.133300262,-2.522695129,-2.046047798,-3.525863576,-1.243172285 -4320,G251M,0.022353993,0.097226344,0.098242918,0.018273782,0.008838474,-0.03178757,-0.021560376,0.066268361,0.074631652,0.004899665,0.189553023,0.052015568,0.144470268,0.011468988,0.025078575,-0.033029122,0.050706069,1.232195707,2.488257928,-7.652187949,-8.070173019,-8.9757407,-6.591430511,-7.923417809,-6.700177704,-8.611842622,-6.49544252 -4321,G251L,-0.06416598,-0.022257134,-0.006624024,-0.01349598,-0.193315119,0.001130294,-0.07295287,-0.05537909,-0.012356544,0.023954774,-0.068469042,0.034874203,-0.048122251,0.010958986,-0.037950946,-0.102543637,-0.2840866,1.364189641,2.335292185,-6.655771393,-6.959609673,-8.30505619,-5.388981194,-6.802414612,-5.822795296,-6.982579722,-4.926629617 -4322,G251N,0.004120294,-0.006098065,0.011532243,-0.041052975,-0.08669194,-0.048788584,0.00564745,0.002593137,-0.088253936,-0.014380384,0.002184255,0.074152439,-0.051087954,-0.035299666,-0.046806284,-0.038108647,-0.135275232,1.443911584,2.594343418,-2.429296396,-3.190290909,-2.699436699,-1.985289871,-1.772748161,-2.498716339,-3.568728107,-0.221089682 -4323,G251Q,-0.002671093,-0.03194097,-0.029632515,-0.033220992,-0.058285538,-0.035206741,-0.022279764,0.016937578,0.069681198,0.024710522,-0.088592461,-0.026835107,-0.032429923,-0.050566422,-0.015875562,-0.075548382,-0.041022694,1.491438144,2.518791003,-2.542327025,-3.420798645,-3.013189301,-1.665512138,-2.426090904,-2.186044136,-3.882472694,-1.808355763 -4324,G251P,-0.020497067,-0.008055659,-0.037718313,-0.019530329,-0.608712558,-0.016795271,-0.032068875,-0.008925259,-0.000851609,0.014636895,-0.030748213,0.007547131,-0.082983756,-0.003401889,-0.035658768,-0.293127036,-0.92429808,1.498034246,2.052949642,-4.084390462,-5.018932632,-4.858112,-3.064411942,-5.063778969,-2.416716766,-4.513094894,-3.062877376 -4325,G251S,-0.06350524,0.001434205,-0.023076917,-0.033503494,-0.065623646,-0.002118176,-0.0669501,-0.060060379,0.011365346,0.046157677,-0.043289268,0.026316666,-0.0724705,0.029465744,-0.096472731,-0.014155504,-0.117091787,1.169552822,2.52275185,-2.865686665,-3.350592239,-2.986963921,-1.937064323,-3.365802307,-2.688010536,-3.487509062,-1.097718043 -4326,G251R,-0.002208394,0.003600906,0.006220392,-0.021013165,-0.056149079,-0.026139448,-0.006939086,0.002522298,0.017270809,0.020344763,-0.013142952,0.028768064,-0.01632728,-0.001884425,-0.040141905,-0.029064659,-0.083233499,1.181127044,2.463725458,-4.146481209,-5.351184555,-4.634647514,-3.175568527,-4.627047325,-2.943958122,-5.408371067,-2.126816248 -4327,G251T,-0.01194882,-0.026391987,-0.038451097,-0.023488552,-0.214043801,-0.056595724,-0.016771423,-0.007126217,0.02670127,-0.031682293,-0.02110168,-0.000661249,-0.076240945,0.011277105,-0.058254208,-0.123457007,-0.304630595,1.360970451,2.280576926,-3.544328354,-4.114020294,-4.012932922,-2.751586357,-3.607063171,-3.236039024,-4.966095978,-1.983958631 -4328,G251W,-0.078074531,-0.028646298,-0.046584939,-0.032309998,-0.899293474,-0.014130346,-0.075245427,-0.080903634,-0.035382045,0.009849495,-0.067142091,-0.001120505,-0.092049372,-0.013268751,-0.051351244,-0.575320908,-1.223266039,0.805156129,1.449951859,-7.169713205,-7.278478889,-8.54142205,-6.2923181,-7.42912513,-6.307221855,-7.879695301,-5.297417607 -4329,G251V,-0.062207818,0.00608112,-0.019932421,-0.008840862,-0.896273514,-0.05705845,-0.069197275,-0.05521836,0.010306275,0.042694362,-0.030532123,0.036777771,-0.076642613,0.038065784,-0.055747507,-0.538965154,-1.253581874,0.60238637,1.406347819,-5.451162943,-6.061244194,-6.135545471,-4.29610775,-5.880513847,-4.88240345,-6.749225586,-3.899877691 -4330,G251Y,0.059122007,-0.016266408,-0.023295325,-0.024735993,-0.181934202,0.035754201,0.084197245,0.034046768,-0.034081435,-0.088482105,0.05594929,-0.025503386,-0.021087264,-0.08540111,0.035929124,-0.182040717,-0.181827687,1.458306636,2.15946925,-6.648239113,-6.484736786,-7.739146469,-6.16349472,-6.951373337,-5.902444252,-7.146648611,-3.453854573 -4331,K252A,-0.063298778,-0.048230377,-0.032751352,-0.031522141,-0.016785141,-0.009214043,-0.071229151,-0.055368404,-0.007681429,-0.004421418,-0.092039336,0.002008809,-0.067511513,0.019317974,-0.082362256,-0.028756043,-0.004814238,1.098853677,2.35255746,-2.944894249,-2.251229347,-2.957151474,-3.202658836,-3.141654511,-3.171777077,-4.032847647,-0.345653435 -4332,K252C,-0.075002662,-0.072096314,-0.068099874,-0.083816649,-0.082285745,-0.062845745,-0.059073358,-0.090931965,-0.060138211,-0.00672643,-0.137466197,-0.008860906,-0.127338842,-0.013121677,-0.15451162,-0.038310904,-0.126260586,1.311443082,2.507118904,-5.424117925,-5.117850403,-4.974972878,-5.585395836,-6.435259682,-5.007110825,-5.552981748,-1.835993024 -4333,K252E,-0.073522291,-0.041302239,-0.033745383,-0.063028645,-0.006253246,-0.018833847,-0.06432579,-0.082718792,0.007874446,0.030374847,-0.112979324,-0.009322283,-0.058168482,-0.012384757,-0.113672532,-0.041920026,0.029413535,1.337439289,2.544722429,-2.721929169,-1.923816208,-2.116819099,-3.233305595,-3.91396402,-2.421740921,-3.833381183,-0.345725204 -4334,K252D,0.051397687,0.073629139,0.113703883,0.070681037,-0.032738769,-0.012087153,0.096671492,0.006123881,-0.071512054,0.196580647,-0.04932237,0.186757736,0.04065003,0.177487706,-0.036125633,0.051674257,-0.117151795,1.027191307,2.886890522,-2.834574042,-2.269511276,-2.247516113,-4.349159828,-4.416551949,-0.890131042,-3.447969414,-0.945135176 -4335,K252G,-0.080162057,-0.050035275,-0.036644239,-0.045233716,-0.029883316,-0.003780304,-0.088717352,-0.071606761,0.012332271,0.002640166,-0.102710716,-0.009650885,-0.063637592,-0.008171017,-0.082296415,-0.055640817,-0.004125814,1.334159116,2.451291407,-1.962827184,-1.157412537,-1.359059143,-3.019998436,-2.491211426,-1.786454376,-3.444826763,2.362656339 -4336,K252F,-0.192987268,-0.029184536,-0.082006255,-0.038731126,-0.051141275,-0.114200371,-0.194048113,-0.191926422,-0.078563521,0.132000591,-0.190369663,0.050175019,-0.214187529,0.191885526,-0.269347777,-0.038663273,-0.063619277,1.217639234,2.643709807,-8.378540112,-7.450734695,-8.202617546,-9.628371346,-8.691528801,-7.919448174,-7.939855438,-5.726879704 -4337,K252I,-0.010280645,0.002251754,-0.040306875,-0.026807661,-0.069459506,-0.079984477,-0.040325056,0.019763766,0.003299526,0.028251154,-0.023747646,0.019228115,-0.099841865,0.028550399,-0.08216572,0.006166936,-0.145085948,1.157564548,2.598516951,-6.229108476,-5.708719727,-5.309199509,-7.59294326,-6.050250626,-6.48442926,-6.346698814,-3.078323424 -4338,K252H,-0.02318934,-0.058681821,-0.074684146,-0.054277842,0.020027393,0.036079591,-0.01189539,-0.03448329,-0.005123261,-0.002453154,-0.114910488,-0.070547854,-0.078820437,-0.052929339,-0.055626345,-0.091135289,0.131190075,1.336667236,2.274121794,-2.959212085,-2.765050369,-3.105084679,-2.849462753,-3.474072739,-2.602389885,-3.979316222,-0.701401036 -4339,K252M,-0.043674401,-0.057648536,-0.037585663,-0.020524079,0.003141287,-0.04663703,-0.036490616,-0.050858185,0.015244958,0.063643129,-0.178940201,0.017916173,-0.093087499,-0.012234456,-0.028813702,-0.009843781,0.016126354,1.258926425,2.531147794,-6.317925389,-5.839417221,-6.121398026,-7.463211555,-6.260962105,-5.904638039,-6.289372718,-3.407850579 -4340,K252L,-0.077578773,-0.043162704,-0.005602598,-0.016085631,-0.011493641,0.017671165,-0.073364912,-0.081792633,0.005518674,0.074210033,-0.16053544,0.067890514,-0.07909571,0.084320886,-0.116492148,0.025785876,-0.048773158,1.114435354,2.802925317,-6.305521643,-5.901751633,-6.016930771,-7.50034388,-5.982432617,-6.126149315,-6.095260801,-3.07599693 -4341,K252N,-0.096134336,-0.023277808,0.004524684,0.027575053,-0.051558233,0.001423884,-0.065717569,-0.126551103,-0.036434899,0.065575477,-0.112131093,0.136341514,-0.127292146,0.11686024,-0.061710134,-0.008953209,-0.094163256,1.177658364,2.682016338,-2.154297289,-2.074240913,-1.445256973,-2.951576012,-2.832109482,-1.468303062,-2.95487503,-0.737818194 -4342,K252Q,-0.068663753,-0.089957717,-0.097607995,-0.078815361,-0.035846092,0.031634368,-0.049666672,-0.087660833,-0.062239695,-0.038501103,-0.141414331,-0.059381691,-0.135834299,-0.057058983,-0.100571739,-0.04643767,-0.025254513,1.352385284,2.410872775,-2.383747905,-1.870189278,-2.456371506,-2.249125092,-3.119037865,-2.224015785,-3.176952287,-0.754621653 -4343,K252P,-0.096829419,-0.072766089,-0.054801683,-0.145968315,-1.765691743,0.044738309,-0.10210816,-0.091550678,-0.006512431,0.00592362,-0.151455798,-0.011460146,-0.098143219,-0.002572565,-0.289364065,-1.561807075,-1.96957641,1.012992491,1.342879475,-4.464865636,-3.799267357,-2.909483688,-6.71058606,-4.633765144,-4.271225929,-5.267360429,-2.098047005 -4344,K252S,-0.047883199,-0.072090165,-0.020917138,-0.033060477,-0.00796242,0.004368757,-0.036084396,-0.059682001,0.013001581,-0.005442854,-0.138737476,-0.004452895,-0.037381381,0.008085577,-0.07420653,-0.058529081,0.042604242,1.197783426,2.32353848,-2.935937447,-3.031436356,-2.669802269,-3.170041519,-3.093028313,-2.715378777,-3.167373335,-0.754782564 -4345,K252R,-0.070875587,-0.064565955,-0.053508451,-0.051573274,-0.008504702,0.019017309,-0.072373248,-0.069377926,0.00689685,-0.007440197,-0.121691713,-0.02298216,-0.084034742,-0.018582856,-0.084563692,-0.04708421,0.030074806,1.347542398,2.499341491,-1.271342799,-0.647958023,-1.613501404,-0.930299484,-1.823906342,-1.341048744,-2.457670217,1.415680518 -4346,K252T,-0.069601721,-0.062847701,-0.032908196,-0.055363587,0.019358697,-0.009995596,-0.059485851,-0.079717591,0.001539934,0.01734889,-0.143044291,-0.011957041,-0.053859351,-0.010835761,-0.099891413,-0.014863896,0.05358129,1.220668345,2.652885092,-3.244180469,-2.834123718,-3.145602211,-4.050336212,-3.014693718,-3.176146484,-3.247074635,-1.455989936 -4347,K252W,-0.107674551,-0.064653971,-0.059512594,-0.061418439,-0.190188435,0.034723095,-0.105197938,-0.110151163,0.023601386,-0.00599669,-0.123311251,-0.028014549,-0.091010638,-0.045592352,-0.077244525,-0.138047905,-0.242328964,1.414912983,2.238588498,-7.84637086,-6.993026436,-7.351992615,-8.93636734,-8.298633087,-7.651834824,-7.677859638,-5.113839542 -4348,K252V,-0.075899315,-0.060956225,-0.042987587,-0.054090333,0.018514735,-0.008826168,-0.082168612,-0.069630018,0.020889991,0.004536879,-0.126449328,0.013636749,-0.099611923,0.008774973,-0.116955639,-0.04098686,0.078016329,1.398183217,2.602703454,-5.383613602,-5.145466751,-4.436731285,-6.445189369,-5.557301048,-5.333379555,-5.539175936,-2.497195834 -4349,K252Y,-0.045335188,-0.02176642,-0.085201251,-0.034060033,-0.124149615,-0.08301449,-0.061634244,-0.029036132,0.013439158,0.065575477,-0.109108316,-0.058184108,-0.112218394,0.032184683,-0.100304748,-0.086450181,-0.161849049,1.324863951,2.368413399,-7.621254179,-6.864759003,-7.593892982,-8.503105026,-8.303756218,-6.840757668,-6.935606703,-4.459813766 -4350,P253A,0.012251763,0.004046874,-0.049954888,0.001008075,0.006098113,0.002563305,0.034396251,-0.009892726,0.019048765,-0.017053484,0.025147232,-0.072545068,-0.027364708,-0.055627577,0.057643727,-0.019307713,0.031503939,1.393583924,2.645540692,-1.183180008,-1.753635544,-1.068589844,-0.862322868,-1.391853096,-0.839498688,-2.421316115,1.412387083 -4351,P253C,0.055546012,-0.028338737,-0.061890196,0.042706591,-0.305743969,-0.005356872,0.080340952,0.030751071,-0.06589953,-0.062646809,0.005969335,-0.08943488,-0.034345512,-0.034744383,0.120157564,-0.239671408,-0.37181653,1.478797805,2.087389375,-7.162550005,-7.383469894,-5.414369301,-7.919471489,-8.548474197,-6.546965141,-8.277241159,-4.32613577 -4352,P253E,0.010219978,-0.035728553,-0.043534252,-0.011474643,-0.717181861,0.007644061,0.02985852,-0.009418565,-0.034446623,-0.092931458,0.021474352,-0.071949533,-0.015118971,-0.062274777,0.039325491,-0.493145382,-0.94121834,1.503440248,1.838586758,-3.265970053,-3.949120201,-1.541419968,-4.053112984,-3.756500137,-3.029696976,-3.975587286,0.234535891 -4353,P253D,0.059739638,-0.011943905,0.023833925,0.075834973,-0.716142335,-0.053063988,0.070135338,0.049343937,-0.053861482,-0.028021399,0.004133589,0.019902153,0.027765696,0.044654837,0.107015108,-0.423199334,-1.009085335,0.830694537,1.519721781,-4.064997838,-4.314715096,-2.632504944,-4.784869652,-4.45723037,-4.135669128,-4.922685774,0.587284226 -4354,P253G,0.014790078,-0.001865262,-0.049057535,0.002782417,-0.466278219,-0.009619127,0.024744547,0.004835608,-0.031698803,-0.023866526,0.020136002,-0.069481861,-0.028633208,-0.042294428,0.047859262,-0.255710732,-0.676845706,1.590887955,2.182387887,-3.819347734,-4.323993485,-2.843828758,-3.497597084,-6.436855804,-1.994463539,-3.983722937,0.434853688 -4355,P253F,0.086370207,0.045527391,-0.030415171,0.042751587,-0.230654709,-0.021286168,0.099053573,0.073686841,0.205825209,-0.043546579,0.13460136,-0.123941504,0.063111163,-0.067574285,0.153077459,-0.263778346,-0.197531072,1.50029886,2.081902257,-8.873667328,-9.000127014,-6.870024422,-9.803485611,-10.71438654,-7.980313057,-8.734950608,-5.071265036 -4356,P253I,-0.052900301,0.111427244,-0.000562932,-0.022065443,-0.22074127,-0.028692014,-0.026009929,-0.079790672,-0.096086603,0.08386577,0.138988717,0.047468436,-0.048594299,-0.069462703,0.025331818,-0.188862228,-0.252620312,1.088285767,1.90400814,-6.516913193,-6.927115761,-4.911028755,-6.550408401,-8.411796066,-5.78421698,-7.170860653,-2.802070194 -4357,P253H,0.050061925,-0.020731181,-0.006215015,0.024640594,-0.214422683,-0.039543166,0.016651223,0.083472627,0.036764458,-0.073884033,0.032421671,-0.051240496,0.038810467,-0.031895146,0.081176333,-0.170401934,-0.258443431,1.426956327,2.188234796,-4.711947948,-4.437181931,-2.842131012,-5.842531395,-6.738975998,-3.698919403,-5.029431052,-0.631755492 -4358,P253K,-0.092022147,-0.033574459,-0.054573214,-0.040507183,-0.549782588,0.063369012,0.004848429,-0.188892723,0.088431145,-0.104156124,0.037007206,-0.078896556,-0.030249871,-0.123460624,0.042446259,-0.238758368,-0.860806807,1.510961587,2.096705522,-2.913037788,-3.070343346,-1.426672089,-3.547653954,-4.621201019,-1.899318535,-2.886349046,1.003505347 -4359,P253M,0.011257346,0.062117335,0.042856146,0.055912677,0.013571918,0.020054438,0.041366539,-0.018851847,-0.042366555,0.120359488,0.003875181,-0.007808219,0.093520511,0.014954032,0.096871321,0.025433383,0.001710452,1.10740376,2.669547104,-6.381919814,-6.808675606,-5.068576752,-6.370821136,-8.360120987,-5.301404587,-7.353758407,-3.55905309 -4360,P253L,0.054985975,0.016183613,-0.050710886,0.008525789,-0.198231325,-0.008437615,0.054447053,0.055524896,-0.002668142,-0.051648933,0.084016159,-0.111925115,0.010503343,-0.085831741,0.102883318,-0.166853784,-0.229608865,1.489267683,2.216193413,-5.087231546,-5.624578377,-3.493128212,-4.831398544,-7.402409355,-4.084643242,-5.850249882,-2.407344024 -4361,P253N,-0.006848344,0.016641298,-0.0565802,0.097143385,-0.397417967,-0.099965727,0.112281499,-0.125978186,0.018594545,-0.018322392,0.051604987,-0.096802314,-0.016358086,0.024505712,0.169781058,-0.301150717,-0.493685216,1.577421983,2.112225657,-4.767049362,-3.783810677,-3.06268428,-6.59066259,-6.174505005,-4.223584259,-5.553341644,-0.733599004 -4362,P253Q,0.049462871,0.018768349,0.029219521,-0.014594246,-0.396652916,-0.016140171,0.033955874,0.064969868,-0.018417553,0.03454081,0.002995888,-0.000623607,0.059062649,-0.065999914,0.036811422,-0.235513227,-0.557792604,1.47460071,2.099275672,-3.332736195,-3.818956291,-1.785659843,-3.825013626,-5.003486649,-2.230564568,-4.304783016,0.111381239 -4363,P253S,0.021242384,0.011666627,-0.022071991,0.027149309,-0.227414653,-0.015050787,0.02595522,0.016529548,0.023405589,-0.027351708,0.050684962,-0.060938064,0.016794083,-0.028061984,0.082360601,-0.169561093,-0.285268213,1.340402463,2.111688785,-2.297471321,-2.227312393,-1.157184227,-3.114279068,-2.641502159,-2.347078758,-3.362897701,-0.014898804 -4364,P253R,-0.01401257,0.000250127,-0.042228405,0.018737438,-0.565616356,-0.017677892,0.007706467,-0.035731606,0.021077841,0.008755427,-0.008255173,-0.035142524,-0.049314285,-0.014739889,0.052214765,-0.268602759,-0.862629952,1.429014611,2.027179926,-3.707861328,-4.537049622,-1.510236343,-4.354681587,-6.020443207,-2.116895882,-4.252243317,1.005104819 -4365,P253T,0.029179069,0.046690771,0.002184782,0.065396688,-0.715523995,-0.045748185,0.030413206,0.027944932,-0.030347032,0.021858982,0.071522559,-0.028366551,0.032736114,0.006250628,0.124542748,-0.357183928,-1.073864062,1.51645171,1.986816098,-3.052827199,-2.831913132,-1.569379105,-3.669974571,-4.919331169,-2.273538017,-4.845598482,0.110036682 -4366,P253W,-0.037056808,-0.030596262,-0.04554463,0.0171003,-1.079928286,0.043655483,-0.028074735,-0.046038881,0.011120805,-0.048948877,-0.012243647,-0.050521588,-0.040567672,-0.014243499,0.048444098,-0.816551421,-1.34330515,0.898412697,1.418467517,-8.975329468,-9.349648933,-6.853794296,-9.876669571,-10.61643506,-8.18009948,-9.538299652,-7.362813533 -4367,P253V,0.021819572,0.044654135,-0.047024014,0.066707238,-0.549257937,0.011396641,0.018737277,0.024901866,0.048471333,0.016058476,0.073249793,-0.058018159,-0.036029869,0.004644354,0.128770122,-0.249636947,-0.848878927,1.286508962,1.934564464,-4.785800819,-5.177059723,-3.861473328,-4.590934937,-6.702271935,-3.597264175,-5.668579191,-1.803706142 -4368,P253Y,-0.0745008,-0.058527189,0.030254291,0.031478213,-0.295745856,-0.006751382,-0.115947414,-0.033054185,-0.104519771,-0.073884033,-0.043170344,0.004002742,0.05650584,-0.016761403,0.079717829,-0.177187923,-0.414303788,1.544767194,2.303887595,-7.938247844,-7.447140923,-5.782701149,-9.386935692,-9.808919777,-7.265541679,-7.446407104,-3.168481174 -4369,S254A,-0.077292263,0.000983708,-0.011320321,-0.008467373,-0.031046557,-0.023272498,-0.051319814,-0.103264712,-0.07277927,-0.014930615,0.016898031,-0.023408427,0.000767785,-0.013541043,-0.003393703,-0.024549009,-0.037544104,1.385481931,2.654527629,-1.12795589,-0.829928703,-1.470694664,-0.647948105,-1.004361473,-1.686846504,-1.367844996,0.538437309 -4370,S254C,0.310455027,-0.007004982,0.037133592,0.066269709,-0.036287842,0.025207875,0.114301004,0.50660905,0.038001544,0.006030164,-0.020040128,0.027525573,0.046741611,0.038016438,0.094522979,-0.023634229,-0.048941455,1.256963482,2.472774749,-5.496786047,-4.049459488,-7.586181007,-4.726432991,-6.148517563,-4.973339188,-5.43698261,-1.797668773 -4371,S254E,-0.036899554,0.031168168,-0.013442752,0.014938513,0.049921103,0.024241605,0.03242132,-0.106220428,-0.056385241,-0.04216237,0.104498706,-0.065669484,0.038783981,-0.01452663,0.044403655,-0.000777732,0.100619937,1.270031354,2.57458469,-2.275311464,-2.09893573,-2.166376701,-2.649638809,-2.011647804,-2.449958275,-2.429855257,-0.758284086 -4372,S254D,-0.126389763,0.016349654,0.02597998,0.021326805,-0.076712443,-0.025699132,-0.08366295,-0.169116576,-0.029026872,0.049999355,-0.017300047,0.011272283,0.040687677,0.027890469,0.01476314,-0.006025949,-0.147398937,1.172658877,2.529951372,-4.684418915,-3.650573128,-5.421602524,-4.458497086,-4.533296173,-5.358125664,-4.881307076,-1.772220686 -4373,S254G,-0.052655547,0.002898513,0.016510204,-0.001368358,-0.019009003,-0.002238129,-0.015467227,-0.089843866,-0.033770192,-0.044732567,0.050529592,-0.032511038,0.065531445,-0.019266923,0.016530208,-0.011016166,-0.027001839,1.195261936,2.412936074,-5.080683073,-3.9800802,-6.495433197,-5.106406624,-4.410954399,-5.410540947,-5.00683039,-1.255956735 -4374,S254F,-0.117804893,0.051457261,0.023072255,0.042608706,-0.852830984,-0.031193571,-0.058092727,-0.177517058,-0.07567012,0.039758914,0.063155607,0.082724514,-0.036580005,0.103862667,-0.018645256,-0.425648374,-1.280013594,0.595856494,1.438500881,-8.330261441,-6.625594742,-10.31722294,-6.750500114,-9.413014572,-8.544974838,-5.956460912,-2.627009621 -4375,S254I,-0.05661823,-0.007425204,0.015648411,0.010908863,-0.158424919,0.027667099,-0.019645645,-0.093590815,0.052220296,-0.039071293,0.024220885,0.054534992,-0.023238171,-0.047313664,0.06913139,-0.179074913,-0.137774924,1.54949492,2.295877772,-6.413307266,-5.588095711,-6.719466049,-6.170454491,-7.098816483,-6.489703598,-5.363408223,-1.943044412 -4376,S254H,-0.14316616,-0.032391106,-0.009945834,-0.036929614,-0.085583908,0.022354368,-0.097735698,-0.188596621,-0.025337418,-0.042921626,-0.021860585,-0.069342474,0.049450806,-0.014680426,-0.059178802,-0.066988605,-0.10417921,1.425478475,2.504198249,-6.384943343,-4.006898911,-8.826061722,-5.521926346,-7.103228676,-6.466601059,-4.148203262,0.65483358 -4377,S254K,-0.004400338,0.002332747,0.055228118,0.041486487,-0.020201976,-0.013236842,0.11082558,-0.119626255,0.026308294,-0.08791986,0.092585354,-0.023139901,0.133596137,-0.001270367,0.08424334,-0.05072504,0.010321089,1.372224252,2.534436454,-3.912220656,-2.789887253,-4.203199333,-4.258769264,-4.727215233,-3.582032196,-4.073441423,0.055035774 -4378,S254M,0.014182076,-0.013020902,0.086502743,0.050960586,-0.089127927,0.065584637,0.081380934,-0.053016782,-0.00674035,-0.042560988,0.016519185,-0.031740073,0.204745558,0.005569058,0.096352114,-0.093974128,-0.084281725,1.383365659,2.376571656,-7.348018112,-6.188415512,-6.859022118,-7.502510902,-8.200231255,-7.989910774,-5.539979402,-2.427726963 -4379,S254L,-0.128108364,-0.029747237,-0.029201441,-0.056561532,-0.121766338,0.01030016,-0.080694876,-0.175521852,-0.02713321,-0.032744969,-0.026749505,-0.033856076,-0.024546806,-0.031927867,-0.081195197,-0.073077219,-0.170455457,1.446109172,2.479097431,-6.851155568,-5.930336563,-5.981504997,-6.917216957,-8.293844353,-7.132874969,-4.661455064,-1.492071131 -4380,S254N,-0.116073703,0.032984761,0.053035575,-0.016518827,-0.060392051,0.037065539,-0.067589645,-0.164557761,0.014983634,0.01353778,0.052431741,-0.002000404,0.108071554,0.034216772,-0.067254425,0.055763259,-0.176547361,0.961157833,2.665501551,-4.63287961,-3.692384003,-5.741531616,-4.403483856,-5.013109245,-4.313889328,-5.130544424,-1.37988286 -4381,S254Q,-0.191922031,-0.070223585,-0.019689468,-0.006666657,-0.011445584,0.085227481,-0.144395188,-0.239448874,-0.001817707,-0.035129107,-0.105318062,-0.003268418,-0.036110517,0.048743025,-0.062076338,-0.002471212,-0.020419955,1.671448915,3.643209181,-5.084573808,-3.38113076,-6.073376801,-5.507773605,-5.093374237,-5.367213638,-4.297280353,-0.555062158 -4382,S254P,-0.094956856,0.009868507,0.001307102,-0.009858871,-1.092810178,0.00704661,-0.056978807,-0.132934904,-0.018359633,-0.024260001,0.043997014,-0.028411304,0.031025508,-0.015586012,-0.00413173,-0.705828329,-1.479792027,0.850535332,1.430519715,-1.38198976,-0.574218079,-1.530211823,-1.114420296,-2.264148735,-1.426949867,-1.873583465,2.769673122 -4383,S254R,-0.013196531,0.012912136,0.011631754,0.00791608,-0.02496754,0.012445058,-0.030680944,0.004287882,-0.040970108,0.007179036,0.018645236,0.015670646,0.007592861,0.0000663,0.015765859,0.003777235,-0.053712314,1.112342145,2.40559552,-5.036340324,-2.818049461,-6.141960625,-5.205154694,-5.237223244,-5.779313599,-4.229749675,1.528386542 -4384,S254T,-0.053628812,0.024137711,0.026426815,-0.026935809,-0.00718497,0.003629904,-0.022896929,-0.084360694,0.002081122,0.000351967,0.047923454,0.007267404,0.045586225,-0.039285253,-0.014586365,0.014073246,-0.028443186,1.231938942,2.654672397,-1.221565979,-0.965376274,-1.25037841,-1.492573975,-1.26765583,-1.131845406,-2.52171576,0.260172409 -4385,S254W,-0.086126758,-0.065814395,-0.031431493,-0.041933604,-0.424733032,-0.06300693,-0.009136165,-0.163117351,0.128188344,-0.007969271,-0.123659518,-0.026261392,-0.036601594,-0.043171811,-0.040695397,-0.146355995,-0.703110068,1.39563807,2.214735936,-8.229243013,-6.465822319,-9.753524216,-7.393716789,-8.563747414,-8.969404327,-5.677194232,-2.891411472 -4386,S254V,-0.091244487,-0.004765805,-0.02258463,-0.002045327,-0.074877584,0.021425578,-0.052848544,-0.129640429,-0.013734615,-0.03485969,0.02532808,-0.047190175,0.002020915,-0.017494421,0.013403768,-0.040700344,-0.109054823,1.224566242,2.396587879,-4.405721613,-4.012061165,-4.500886276,-4.491062187,-4.130973648,-4.893624786,-4.032980198,-0.545677014 -4387,S254Y,-0.168858004,-0.081374518,-0.018126134,-0.013225464,-0.647275314,0.089898805,-0.060481899,-0.277234109,0.002483705,-0.110782743,-0.051966293,-0.086302352,0.050050085,-0.067942287,0.04149136,-0.418995125,-0.875555503,1.54175309,1.950274203,-8.201130724,-5.500169571,-11.64448792,-6.505533691,-8.652663628,-8.702798813,-5.678352814,-1.017984998 -4388,R255A,-0.043378499,-0.021511048,-0.031945101,-1.216678493,-2.085895793,0.01367479,-0.052926668,-0.033830329,0.015042969,-0.004727191,-0.038294904,-0.018390782,-0.045499419,-0.63709957,-1.796257415,-2.058506898,-2.113284687,1.813336363,1.39882025,-6.764009561,-7.458838936,-6.545634781,-5.966463982,-7.151590378,-6.69751973,-5.417006598,0.616571469 -4389,R255C,-0.020210327,-0.031898994,-0.026925435,-1.112463686,-2.442376616,0.024466855,-0.016416206,-0.024004448,0.058054618,0.005031494,-0.068829481,-0.013214073,-0.040636796,-0.625969636,-1.598957735,-2.132883613,-2.751869619,1.751195191,1.355167747,-8.855382387,-10.32537157,-9.100717941,-8.611462105,-7.461926361,-8.777433952,-7.026274695,-0.786819372 -4390,R255E,-0.08684752,-0.097438824,-0.166490792,-1.75262398,-2.826118507,-0.067699275,-0.091020254,-0.082674785,-0.014210572,-0.07037572,-0.124501927,-0.089647162,-0.243334421,-1.232235937,-2.273012022,-2.675996114,-2.976240899,0.775369457,0.732449195,-10.56357408,-11.56331415,-10.35561404,-10.412143,-11.56554111,-8.921258102,-8.530136,-3.638000043 -4391,R255D,-0.039089437,-0.90444169,-2.10411754,-2.51920936,-2.577336579,0.014710282,-0.020923762,-0.057255112,0.045977008,-0.403046202,-1.405837178,-2.371060997,-1.837174082,-2.45542186,-2.58299686,-2.537454201,-2.617218957,0.339508504,-0.468969671,-11.12075656,-12.18770659,-10.55042397,-10.67306437,-11.8287181,-10.36386977,-9.405761067,-5.994013933 -4392,R255G,-0.035516339,-0.019530771,-0.988709271,-1.929591186,-2.607993029,-0.02390448,-0.030780765,-0.040251912,-0.049704622,0.00465833,-0.043719871,-0.448581062,-1.528837479,-1.77640764,-2.082774731,-2.366595469,-2.849390588,1.67396494,0.820922088,-9.823540735,-10.21552294,-10.01343985,-9.269761879,-9.988492256,-9.630486748,-7.823932748,-1.89537733 -4393,R255F,0.023336492,0.009398449,-0.919561626,-1.885576062,-2.876353994,-0.016047875,-0.000824997,0.047497981,-0.049030082,0.080580016,-0.061783119,-0.491628169,-1.347495083,-1.948901035,-1.822251089,-2.252782125,-3.499925862,1.599421168,0.744113022,-6.700698158,-7.297774948,-6.17204464,-6.26757737,-7.3728741,-6.393219734,-5.224133976,2.26768469 -4394,R255I,-0.05677605,-0.001571475,-0.047934729,-0.296151688,-1.681474147,-0.1102707,-0.157075992,0.043523893,-0.048329183,0.028180258,-0.031323207,-0.017357306,-0.078512151,-0.025329823,-0.566973553,-2.200783849,-1.162164445,0.693807386,1.283077579,-6.17004744,-8.280233871,-5.520994736,-5.557661102,-7.311126709,-4.180220779,-3.628858703,3.013830689 -4395,R255H,-0.029324962,-0.016389397,-0.029693857,-0.476169951,-1.895191031,-0.029426251,-0.043124813,-0.01552511,-0.053482375,0.000282716,-0.03306151,-0.002237421,-0.057150293,0.005624116,-0.957964017,-1.614926104,-2.175455957,0.592780347,1.309902125,-3.799865906,-3.801072433,-3.650109695,-4.00339782,-4.423513123,-3.121236458,-5.767567696,-1.120295891 -4396,R255K,0.029245343,-0.056909649,-0.082790346,-0.03681639,-0.027408632,-0.033182869,0.003948473,0.054542212,0.011837503,-0.061972562,-0.051846736,-0.009487962,-0.156092729,-0.064226359,-0.00940642,-0.059977113,0.00515985,1.224864098,2.236257546,-6.604129268,-6.487511215,-6.709932335,-6.760024948,-6.94784359,-6.115334251,-7.153557988,-2.07633807 -4397,R255M,-0.001651074,0.032912732,-0.028043944,-0.245939811,-2.10091888,0.016102622,-0.017103209,0.013801062,0.048355164,0.010065858,0.055759606,-0.076343319,0.020255431,-0.018427231,-0.473452391,-1.648058485,-2.553779275,0.748983301,1.316677466,-7.876791554,-9.229757027,-8.574009911,-7.415159111,-8.303513794,-5.861517929,-4.889192212,0.146158974 -4398,R255L,-0.032645135,-0.026034758,-0.028104442,-0.378602858,-1.841853145,0.036097152,-0.040346072,-0.024944198,-0.009133783,-0.021284214,-0.030785302,-0.009055568,-0.047153315,-0.053666649,-0.703539067,-1.65395977,-2.02974652,0.707906748,1.313784227,-5.912760696,-6.981705872,-7.856859055,-5.39116188,-3.74528701,-5.588789665,-4.080862587,2.723804346 -4399,R255N,-0.014402288,-0.035500676,-1.025941744,-1.85328601,-2.618899902,-0.009017172,-0.016501092,-0.012303483,0.01147398,-0.032706447,-0.038294904,-0.737153639,-1.314729848,-1.997605761,-1.708966258,-2.079638101,-3.158161702,3.578366533,2.24752255,-10.07719632,-10.0060732,-10.40572917,-10.10155185,-11.30015036,-8.57247702,-9.378161197,-5.85321931 -4400,R255Q,-0.040554365,0.008872005,0.000318864,-1.258097567,-2.147603701,0.003432691,-0.049386124,-0.031722605,-0.033629801,0.037599935,-0.019855925,0.028709668,-0.02807194,-0.746093405,-1.770101729,-1.782368254,-2.512839148,2.072798894,1.576867771,-6.589488536,-7.422879501,-6.996257385,-6.000133591,-6.953653572,-5.574518631,-7.279640937,-2.224759213 -4401,R255P,-0.007059464,-1.750263954,-2.222086659,-2.280465519,-3.355304615,-0.020685797,-0.021377765,0.007258838,-0.085706332,-1.830525753,-1.670002154,-1.991456736,-2.452716581,-2.110579705,-2.450351332,-2.970763296,-3.739845934,-0.30828932,-1.098126239,-11.0943509,-11.60364522,-11.20846322,-10.58815392,-11.53673878,-10.53475333,-9.405761067,-5.994013933 -4402,R255S,-0.01805155,-0.003711798,-0.024266618,-1.248414034,-2.797274372,-0.014074367,-0.017392992,-0.018710108,-0.023558978,-0.016855271,0.009431676,-0.023265533,-0.025267702,-0.804820142,-1.692007926,-2.701987299,-2.892561445,0.798030178,0.790074973,-8.947214819,-8.844811722,-8.350699028,-8.574395493,-9.854117287,-9.112050568,-7.292145709,-2.297251214 -4403,R255T,-0.002236586,0.004703486,-0.072025036,-1.067756336,-2.500235922,-0.077486434,-0.017656074,0.013182902,-0.035228051,0.044229395,-0.034822424,-0.039362182,-0.104687889,-0.467505021,-1.66800765,-2.011935359,-2.988536485,1.689861255,1.382826613,-7.327070473,-8.372932175,-6.30394352,-7.0119114,-7.762431702,-7.184133568,-5.652982322,-0.946084923 -4404,R255W,-0.011575322,-0.666995458,-1.952554295,-2.033142725,-2.741784941,0.054773447,-0.009266896,-0.013883747,0.007532686,-0.255093672,-1.078897244,-1.947716409,-1.95739218,-1.855986013,-2.210299436,-2.415139608,-3.068430274,0.959112405,-0.092401791,-5.317202786,-6.016811287,-5.845949615,-5.247691368,-6.065923088,-3.409638573,-4.450118478,0.478342556 -4405,R255V,-0.043340984,0.006080136,-0.009585314,-0.26264843,-1.555218978,-0.006724663,-0.059685679,-0.026996289,0.0018514,0.045123859,-0.032963587,0.035183174,-0.054353801,-0.008278801,-0.517018058,-1.466098292,-1.644339663,0.565240506,1.314980287,-5.568502373,-6.840176743,-5.529785744,-4.516499321,-6.297876823,-4.658173233,-4.015973635,2.625701946 -4406,R255Y,-0.001309946,-0.087036091,-1.401495964,-2.516795098,-2.256511268,-0.043019517,-0.000895664,-0.001724227,0.0565202,0.024387269,-0.198459451,-1.192495119,-1.610496808,-2.00385471,-3.029735486,-2.261978309,-2.251044226,3.124234435,1.652400386,-4.858955217,-5.413916603,-4.329925949,-5.657278549,-5.138023796,-3.755631187,-4.463659044,3.230712209 -4407,I256A,0.051827108,0.032781448,0.028515986,-0.026911959,-1.780513259,-0.007461,0.085134343,0.018519873,0.014202818,-0.013334349,0.078897244,-0.017426233,0.074458205,0.033923297,-0.087747214,-1.582177504,-1.978849013,0.62849743,1.312632839,-7.433812068,-6.496695755,-5.36975872,-12.23994312,-7.306442383,-5.75622036,-4.924034397,0.251557375 -4408,I256C,0.198037186,0.066207122,-0.020877817,0.063026065,-1.213999249,-0.061310116,0.207916109,0.188158262,0.042913202,0.031156301,0.101257943,-0.072824411,0.031068778,0.031302258,0.094749871,-1.3230322,-1.104966297,0.706428419,1.331148838,-9.957338533,-8.111836128,-7.830223701,-13.65027501,-9.297541077,-10.89681675,-6.806913344,-3.802028226 -4409,I256E,0.005147858,-0.169800372,-1.443462953,-2.404500518,-2.946681611,0.014501176,0.026545743,-0.016250028,0.003828572,0.041374097,-0.38097484,-1.305857327,-1.581068579,-2.392062357,-2.416938679,-3.130096384,-2.763266838,0.47201495,0.05578944,-12.6554328,-11.06546815,-9.927366623,-16.17915937,-11.86462607,-14.24054379,-7.205438059,-4.383338101 -4410,I256D,0.103227099,-1.708667337,-1.665553438,-2.411804575,-2.347045758,-0.043637456,0.087080099,0.119374099,-0.113366288,-1.276122644,-2.141212029,-1.683607971,-1.647498904,-2.20554157,-2.618067579,-2.341515606,-2.352575909,4.026599353,1.856402392,-13.93676651,-11.8235308,-11.46996103,-17.81575994,-13.22846011,-15.34612065,-8.657203444,-6.396043462 -4411,I256G,0.052258855,0.028385392,-0.757248183,-1.594615108,-2.507533621,-0.049460732,0.077851455,0.026666254,-0.026400958,-0.013208397,0.06997918,-0.411807593,-1.102688772,-1.390459201,-1.798771015,-2.286101082,-2.72896616,2.49432858,1.500189233,-11.4852279,-9.447622063,-8.45546917,-16.70241387,-11.17613887,-11.64449554,-6.895650516,-3.901546032 -4412,I256F,0.036034788,-0.014061129,-0.049811853,-0.010366645,-1.443576474,-0.041818615,0.044981069,0.027088506,0.030505329,-0.059037684,0.030915427,-0.068583002,-0.031040703,-0.005387774,-0.015345515,-1.400637058,-1.486515889,0.752666071,1.330614689,-4.65080755,-3.05035511,-3.600396744,-7.014225288,-4.731539215,-4.857521393,-4.203818676,-1.696081492 -4413,I256H,-0.021972134,-1.068175856,-2.219644999,-2.216740859,-2.978588299,-0.07486626,-0.060603228,0.016658961,-0.008011118,-0.945904259,-1.190447453,-2.149269603,-2.290020395,-2.495111943,-1.938369775,-2.631085979,-3.326090618,0.566180384,-0.60104993,-13.47177684,-11.87922249,-9.942826744,-16.64503691,-12.14428346,-16.7475146,-7.782838145,-5.347386473 -4414,I256K,0.038237877,-1.798913843,-1.979943712,-2.4831568,-2.778477635,-0.066418375,0.056527048,0.019948705,-0.033396951,-1.825098023,-1.772729662,-2.01870353,-1.941183894,-2.540637129,-2.425676471,-2.852702424,-2.704252845,-0.665803239,-1.079945192,-13.47039813,-11.23474399,-10.72886097,-16.4193326,-11.84661171,-17.12244137,-8.655554336,-6.402563799 -4415,I256M,0.023897928,0.021976203,0.019730043,0.019270674,-0.857250367,-0.036256949,0.031290881,0.016504974,-0.041787621,0.030489068,0.013463337,0.027548473,0.011911613,0.041148049,-0.002606701,-0.615165563,-1.099335171,0.651828558,1.40046959,-5.291553201,-4.705943512,-4.787464027,-6.685430229,-5.147003479,-5.131924759,-5.331084218,-3.350200396 -4416,I256L,0.062237257,-0.001544763,0.030183308,0.013804997,0.031781474,-0.031328813,0.071661252,0.052813261,0.013850616,-0.034848385,0.03175886,-0.023670135,0.08403675,0.008429511,0.019180482,-0.067632949,0.131195897,1.374693967,2.393562958,-2.155813625,-1.446231056,-1.917934174,-2.847155426,-2.197679077,-2.37006839,-2.62369923,-0.374241452 -4417,I256N,0.055310148,-0.562821218,-1.549088989,-2.134230479,-2.785153544,0.002237775,0.024916569,0.085703727,0.041503808,-0.235319632,-0.890322803,-1.606592786,-1.491585192,-2.350375135,-1.918085822,-2.486349171,-3.083957916,1.147538348,0.056500034,-13.0310496,-10.70349392,-10.14103234,-16.84293498,-12.34826796,-15.11951881,-8.127703815,-5.743080662 -4418,I256Q,0.071591266,-0.422695555,-1.629327007,-2.225063146,-3.321413976,-0.026934063,0.071663129,0.071519403,-0.00127215,-0.206701235,-0.638689874,-1.509451211,-1.749202803,-2.177512846,-2.272613446,-3.012456886,-3.630371066,1.143897832,0.092580271,-12.8270351,-10.87824624,-10.06537879,-16.14246511,-10.87328754,-16.17579784,-8.059054464,-5.732600856 -4419,I256P,0.016773053,-1.705005674,-1.939423489,-2.783821948,-2.864080437,-0.013803252,0.027422807,0.006123298,-0.105868458,-1.811646915,-1.598364432,-1.845551579,-2.033295399,-3.004307275,-2.563336621,-2.839251316,-2.888909558,-0.076987674,-1.094807931,-11.80632752,-10.51545722,-9.405980995,-15.86023612,-11.12081293,-12.12915034,-7.856497326,-5.650543341 -4420,I256S,0.013634515,-0.09314712,-1.345616633,-2.033570791,-2.721386964,-0.025374945,0.030277409,-0.00300838,-0.05700068,0.030353639,-0.216647878,-1.064450768,-1.626782497,-1.987529516,-2.079612066,-2.600624807,-2.84214912,2.237435148,0.907175206,-10.03763713,-7.948071854,-7.537128479,-15.13409908,-9.138651497,-10.43023474,-6.506612854,-2.448623204 -4421,I256R,0.024502273,-1.765997758,-2.034737441,-2.223594437,-3.003933659,-0.038277322,0.056633267,-0.007628722,-0.101842839,-1.69165777,-1.840337745,-2.213086449,-1.856388433,-2.111770758,-2.335418115,-2.694902825,-3.312964493,-0.215403361,-1.085100257,-14.00122744,-11.31260469,-10.91593624,-16.80795244,-12.68227671,-18.28736711,-8.739979436,-6.402563692 -4422,I256T,0.043519472,-0.028753043,-0.12651782,-1.80799367,-2.782825476,-0.036170131,0.054606881,0.032432062,-0.01449531,-0.060331858,0.002825773,-0.053096996,-0.199938644,-1.457112201,-2.158875139,-2.371237487,-3.194413464,0.856921096,0.720312134,-8.259118475,-6.686589836,-6.272687027,-11.2548152,-7.358060715,-9.723439598,-5.733026662,-1.829980766 -4423,I256W,-0.002092181,-0.400519562,-1.540245048,-2.117686485,-2.886654143,-0.014054039,0.013850848,-0.018035209,0.018394191,-0.11983741,-0.681201714,-1.525344171,-1.555145924,-2.213609192,-2.021763777,-2.349583227,-3.423725059,0.859555605,0.045686776,-10.8655734,-8.677658821,-9.192047974,-13.90670571,-10.70988857,-11.84156593,-8.075393361,-6.07463222 -4424,I256V,0.081971834,0.037195419,0.043297259,0.054170102,0.061372291,-0.012270832,0.106788023,0.057155644,0.028964366,0.052220008,0.022170829,0.002612947,0.08398157,0.062097867,0.046242336,-0.010173374,0.132917955,1.168857941,2.575663944,-3.153038316,-2.079240578,-3.033088989,-4.514507225,-5.044824028,-1.093530762,-2.839521754,0.693272718 -4425,I256Y,0.075536046,-0.04869162,-0.048438368,-1.681059859,-2.204346671,-0.039112489,0.063124083,0.087948009,-0.060388074,-0.042844433,-0.054538807,-0.074369395,-0.022507341,-1.080602833,-2.281516884,-2.216576869,-2.192116473,2.124409129,1.401980453,-7.661777954,-5.80120108,-5.262743782,-9.73363813,-7.339888733,-10.17141805,-5.625650022,-1.337598181 -4426,V257A,-0.062846113,0.009135987,-0.025366832,0.038927332,-1.343045238,-0.080772329,-0.089593884,-0.036098342,-0.021947092,0.060833274,-0.042561301,0.002038745,-0.052772409,0.0513436,0.026511063,-0.994964153,-1.691126322,0.564277681,1.338527944,-2.714186549,-3.462495377,-1.971668983,-1.875369057,-3.993485786,-2.267913544,-2.875520186,-1.41286227 -4427,V257C,-0.02382735,0.01253483,0.014347871,-0.006045967,-0.455446835,-0.075916292,-0.030958596,-0.016696103,-0.017814177,-0.004335815,0.029405474,-0.015978525,0.044674266,-0.044724393,0.032632459,-0.279953194,-0.630940475,1.652846723,2.193288383,-8.768818382,-9.036265373,-8.600427231,-7.191651268,-9.474199593,-9.541548447,-7.161952692,-4.872525793 -4428,V257E,-0.041742284,0.01345266,-0.908424279,-1.984113868,-2.441804656,-0.088845402,-0.059542826,-0.023941741,-0.043445341,0.048502275,-0.021596956,-0.376369187,-1.44047937,-2.092346657,-1.875881078,-2.388531883,-2.495077428,1.377437673,0.673649424,-9.501699553,-9.584389465,-8.739932808,-8.268553123,-10.51002628,-10.40559608,-8.51471993,-6.90408859 -4429,V257D,-0.082873453,-1.353018439,-2.243443264,-2.512696794,-2.984401943,-0.129990974,-0.099693735,-0.06605317,-0.036376229,-1.025896326,-1.680140552,-2.406646061,-2.080240466,-1.99877189,-3.026621697,-2.595987111,-3.372816775,0.588082547,-0.639125778,-10.71917166,-11.31560867,-9.969042465,-9.304372047,-11.23815971,-11.7686754,-9.320356452,-9.424452596 -4430,V257G,-0.044010181,-0.358524952,-1.735548553,-2.342862979,-3.164053131,-0.083181745,-0.066360354,-0.021660007,-0.063625609,-0.051807844,-0.66524206,-1.559547781,-1.911549324,-2.068127559,-2.617598399,-2.489251521,-3.83885474,0.697280776,0.02854432,-9.091801323,-9.664670334,-8.116621559,-7.763987053,-9.668850479,-10.24487719,-7.019112354,-4.187521179 -4431,V257F,-0.004322956,0.030132396,0.040317763,-0.761731632,-2.091013819,-0.155540575,-0.014798673,0.006152762,-0.03512635,0.059587027,0.000677764,0.067734713,0.012900812,-0.179758941,-1.343704322,-1.882889662,-2.299137976,1.127415114,1.325951007,-8.226717221,-10.08991094,-8.058535858,-6.417245857,-8.096517044,-8.471376404,-5.324322302,-1.944202156 -4432,V257I,-0.008981849,0.057217543,0.044391774,0.077527434,0.058652177,-0.123336658,-0.051078701,0.033115004,-0.063747374,0.041785392,0.072649694,0.050876883,0.037906664,0.026386116,0.128668752,0.010106017,0.107198336,1.217427388,2.698016862,-1.931757492,-1.744709969,-0.834241707,-2.929900665,-2.756873085,-1.393062035,-3.886400098,0.022869919 -4433,V257H,-0.080310339,-0.436173308,-1.742518388,-2.085803186,-3.009053329,-0.129793569,-0.069814685,-0.090805993,-0.054598868,-0.129074478,-0.743272138,-1.501706323,-1.983330453,-2.22416592,-1.947440451,-2.645289883,-3.372816775,0.902334284,0.055703276,-11.80556571,-11.92361539,-11.95006438,-10.44299136,-11.56061842,-13.15053901,-9.320356452,-9.424453515 -4434,V257K,-0.086502358,-1.563469608,-2.065668699,-2.232862238,-2.792613017,-0.10159075,-0.051710264,-0.121294452,-0.017542764,-1.476094938,-1.650844277,-1.902602163,-2.228735235,-2.448970501,-2.016753974,-2.569064469,-3.016161565,0.062924703,-0.891421928,-9.652694594,-10.24142681,-9.338001678,-8.076927246,-9.939060051,-10.66805718,-8.052853102,-6.082410644 -4435,V257M,-0.088438546,-0.02629171,-0.069212771,-0.211288039,-1.704118253,-0.089092903,-0.080417006,-0.096460085,0.0189849,0.005467643,-0.058051062,-0.030398812,-0.10802673,-0.040551211,-0.382024866,-1.648169194,-1.760067311,0.802579593,1.318570145,-4.270540999,-5.367645096,-4.818829353,-2.060260826,-4.518345139,-4.58762458,-3.576214555,-1.927183307 -4436,V257L,-0.028215561,0.000320649,0.006455306,0.026319666,-0.681760256,-0.097560527,-0.015758036,-0.040673085,0.004828397,0.0355556,-0.034914302,0.002410574,0.010500037,-0.014851498,0.06749083,-0.379877848,-0.983642663,0.75828416,1.49911456,-4.491599248,-4.541692436,-4.545428841,-3.27125058,-4.596743813,-5.502880569,-3.509405564,-0.04004435 -4437,V257N,-0.068721636,-0.058192795,-1.427418495,-2.074132729,-2.696352876,-0.109587021,-0.077363985,-0.060079287,-0.12111191,0.075552175,-0.191937764,-1.118640867,-1.736196122,-1.555864735,-2.592400722,-2.153079957,-3.239625795,3.727471903,2.413897355,-10.86052006,-11.26527186,-10.86047649,-9.106927582,-10.81933268,-12.25059168,-9.320356452,-9.424451693 -4438,V257Q,-0.035185518,-0.462269761,-2.050790248,-2.28315067,-2.905370818,-0.056762927,-0.034089646,-0.03628139,-0.05762683,-0.135361379,-0.789178142,-2.050889082,-2.050691413,-1.81910617,-2.74719517,-2.416321392,-3.394420243,0.70545624,-0.166821964,-10.52989763,-11.07927316,-9.956786301,-8.72244664,-11.01993928,-11.87104279,-9.320356452,-9.424452843 -4439,V257P,-0.042546461,-1.850788402,-1.967061522,-2.267606043,-2.898690575,-0.08021822,-0.063755297,-0.021337625,-0.093665108,-1.890874014,-1.81070279,-1.974958559,-1.959164484,-2.307447077,-2.227765009,-2.72857104,-3.068810109,-0.207186864,-1.123392367,-10.26252365,-10.90929496,-10.01629845,-8.924765327,-10.44028224,-11.02197726,-9.294577264,-9.2852372 -4440,V257S,-0.033437742,0.013148696,-0.087842372,-1.631323837,-2.146463024,-0.125518259,-0.019530225,-0.047345258,-0.031020072,0.047099543,-0.020802151,-0.009979215,-0.165705529,-1.277111134,-1.985536539,-2.006951921,-2.285974126,2.435679438,1.628918756,-8.553231488,-8.782029839,-7.670635178,-7.282049339,-9.010026031,-10.02141705,-8.035250224,-6.217817909 -4441,V257R,-0.040648226,-1.69158832,-2.100052307,-2.512926692,-3.192118516,-0.110480578,-0.05641681,-0.024879642,-0.142539584,-1.611560425,-1.771616214,-2.02103431,-2.179070303,-2.727103492,-2.298749892,-3.023288718,-3.360948314,0.02435984,-1.059920302,-10.83918245,-11.79571456,-10.22910677,-8.811691681,-10.97670217,-12.38269705,-9.320356452,-9.42445405 -4442,V257T,-0.022687518,0.031765812,-0.003675796,0.033407879,-1.444969154,-0.102878351,-0.045372996,-0.00000204,-0.018304145,0.045376804,0.018154819,-0.005998705,-0.001352887,0.016524585,0.050291173,-1.2401521,-1.649786208,0.641690298,1.331051839,-5.481109235,-5.969787338,-4.398807648,-4.725731224,-6.230211922,-6.081008041,-5.837710362,-5.132698545 -4443,V257W,-0.010309487,-0.130065334,-1.320807478,-2.364907408,-3.09805193,-0.077496879,-0.004148059,-0.016470915,-0.054790822,-0.000988975,-0.259141692,-1.209135778,-1.432479177,-2.46871456,-2.261100255,-2.588808527,-3.607295333,0.692807421,0.08391108,-9.099029944,-10.74026165,-9.694339127,-6.824430244,-7.136149147,-11.09996955,-6.736472433,-4.848250572 -4444,V257Y,-0.033432459,0.026914689,0.004857024,-0.599132978,-2.144536152,-0.1557989,-0.018161972,-0.048702946,0.014009988,0.02936388,0.024465498,0.034009647,-0.024295599,-0.136029831,-1.062236124,-2.168168628,-2.120903676,0.983218865,1.292517849,-9.763068236,-10.91373839,-9.916742836,-7.659291,-9.584347031,-10.74122192,-6.362736685,-3.835443549 -4445,V258A,0.011156456,-0.037557101,-0.012404448,-0.010520429,-0.177366222,0.008301585,0.022968355,-0.000655443,-0.003524956,-0.09853407,0.023419869,-0.093892594,0.069083699,-0.097263303,0.076222446,-0.158922167,-0.195810276,1.254158012,2.057825486,-1.911300558,-1.556061859,-2.143498047,-1.959875732,-3.257089104,-0.63997805,-2.174253353,1.171373905 -4446,V258C,-0.018717432,0.009073619,-0.007921426,-0.011224001,0.008712792,-0.061409171,-0.035445372,-0.001989491,0.041428406,0.002253585,0.015893653,-0.037539324,0.021696472,-0.066794656,0.044346655,-0.005867424,0.023293007,1.197048079,2.424241261,-4.712414476,-5.781599724,-5.057299484,-6.202072144,-5.25176429,-1.269336739,-3.837922024,-1.320999984 -4447,V258E,-0.015774562,-0.944824207,-1.60816998,-2.014435697,-2.065323516,0.014432217,-0.01810288,-0.013446244,0.131204697,-0.714213136,-1.175435278,-2.067992024,-1.148347935,-2.145255082,-1.883616312,-2.193191676,-1.937455356,0.325773789,-0.549919549,-9.812441168,-10.94028965,-9.141573326,-10.40591979,-10.52433689,-8.050086182,-8.869157542,-8.970034247 -4448,V258D,-0.068870506,-0.470390938,-1.5694502,-2.502142071,-2.373518919,0.072621793,-0.034412259,-0.103328753,-0.015472941,-0.152416325,-0.78836555,-1.30207523,-1.836825169,-2.282428275,-2.721855866,-2.330364869,-2.416672968,1.28111415,0.173289599,-10.27886536,-11.60921671,-9.857236145,-11.00237828,-10.78362315,-8.141872498,-8.869157542,-8.970034247 -4449,V258G,0.023264172,-0.009486249,0.028035025,-0.028698542,-1.458193585,0.021480389,0.054493424,-0.007965081,-0.067281039,-0.072737257,0.05376476,-0.033343177,0.089413227,-0.015739965,-0.041657118,-1.445529748,-1.470857422,0.640104292,1.320111614,-6.36409883,-8.148089623,-4.638996719,-7.801269997,-7.068557281,-4.163580528,-4.628691125,-1.652321088 -4450,V258F,-0.02695794,-0.072463513,-1.016334774,-1.912312187,-2.973794655,0.014139712,-0.012327423,-0.041588456,-0.0115076,-0.112268023,-0.032659002,-0.640933468,-1.39173608,-1.900040114,-1.924584259,-2.646946712,-3.300642598,1.903055209,0.839895841,-8.159495699,-8.178966293,-7.291431519,-10.23924332,-8.229853546,-6.857983818,-7.456535221,-5.28664883 -4451,V258I,0.025468746,0.005903626,0.046390745,0.057771834,0.08894501,0.011885737,0.027616647,0.023320845,-0.05705482,0.037067969,-0.025260718,-0.045019172,0.137800661,0.011466028,0.104077639,0.026722574,0.151167446,1.122961387,2.648329456,-2.837062004,-3.272535721,-2.635758049,-3.103370132,-2.60539283,-2.568253288,-4.443180197,-2.820512789 -4452,V258H,-0.023263239,-1.746735511,-2.124489571,-2.492014558,-2.84051266,0.018897637,-0.002869443,-0.043657035,-0.055560841,-1.615230115,-1.878240907,-2.64449791,-1.604481231,-2.721760969,-2.262268146,-2.167637572,-3.513387748,-0.178746375,-1.048045647,-10.76859557,-12.46103688,-10.15658785,-12.14659917,-10.82327518,-8.255478775,-8.869157542,-8.970034247 -4453,V258K,-0.108847708,-1.749487373,-2.189710801,-2.131267056,-2.454188897,0.09791333,0.035919825,-0.25361524,-0.12450232,-1.903743553,-1.595231193,-1.978768839,-2.400652763,-2.056031897,-2.206502214,-2.103968492,-2.804409302,-0.513134159,-1.157154373,-9.697293892,-11.09576365,-8.75182576,-10.46795579,-9.957396942,-8.213527321,-8.869157542,-8.970034247 -4454,V258M,0.044475455,-0.018800871,0.063767046,-1.551866724,-1.778547728,-0.027442312,0.085426914,0.003523995,-0.049800065,-0.130283522,0.092681781,-0.080370072,0.207904163,-1.26899906,-1.834734387,-1.953757752,-1.603337703,2.802316674,1.924474037,-7.292954982,-7.653502045,-7.290457863,-7.360493423,-7.459300461,-6.701021118,-8.071640502,-6.359088587 -4455,V258L,-0.042224828,-0.016140287,0.002872292,-0.10385262,-1.794191325,0.034355759,-0.000667318,-0.083782337,0.001456318,-0.066058377,0.033777804,-0.075365248,0.081109832,-0.058993648,-0.148711591,-1.567765466,-2.020617184,0.873126661,1.329927128,-5.37998071,-5.845997665,-5.186815826,-6.118746544,-5.438030716,-4.310312798,-6.631345636,-4.442615867 -4456,V258N,0.014440329,0.028436231,-1.484851215,-2.019225758,-1.857129212,-0.009163236,0.055335371,-0.026454713,-0.03533557,-0.073622669,0.130495131,-0.632018159,-2.337684271,-2.071009053,-1.967442463,-2.118945648,-1.595312775,1.745784432,0.746845854,-9.400452722,-10.86129948,-9.209705589,-10.35011768,-9.414715408,-7.166425453,-7.469053599,-6.181368523 -4457,V258Q,-0.02099978,-1.426388455,-1.74957028,-2.230717157,-2.704153997,0.00826016,0.050375669,-0.092375228,0.008256798,-1.035164417,-1.817612492,-1.779196484,-1.719944075,-2.032550801,-2.428883513,-2.381517392,-3.026790602,3.561134479,1.522546158,-9.587688527,-10.85359924,-9.264304085,-10.06813582,-9.748970642,-8.003432854,-8.869157542,-8.970034247 -4458,V258P,-0.018105437,-1.57710817,-2.189313586,-2.289391174,-3.324957823,0.016651187,-0.009673209,-0.026537665,-0.04318869,-1.662935837,-1.491280502,-2.462866862,-1.91576031,-2.331853978,-2.246928369,-2.856911827,-3.793003819,-0.452402176,-1.070980582,-10.03341904,-10.80267217,-10.13754273,-10.62183828,-10.41294646,-8.192095543,-8.869157542,-8.970034247 -4459,V258S,-0.037276498,-0.010526519,0.015465571,-0.454231122,-1.671132712,0.030478504,-0.025397058,-0.049155938,0.005072538,-0.041478483,0.020425445,-0.043322384,0.074253525,-0.159952519,-0.748509724,-1.606371651,-1.735893773,1.06534406,1.346040079,-3.355622102,-4.493235024,-3.188994019,-4.722121445,-3.077992966,-1.295767059,-3.101188026,-0.157095319 -4460,V258R,-0.041351078,-1.465487238,-2.213527065,-2.188556715,-3.037054817,0.032889579,-0.031125887,-0.051576269,-0.036773783,-1.539075323,-1.391899152,-2.551952703,-1.875101427,-2.328185765,-2.048927664,-2.853243614,-3.22086602,-0.036481562,-0.995451062,-9.985415871,-11.22357582,-10.02437411,-10.35377822,-10.09021977,-8.235131432,-8.805311322,-8.514037598 -4461,V258T,-0.047506798,-0.016114093,0.014154373,0.013067529,-1.145976647,0.051724857,0.005897397,-0.100910992,0.015556037,-0.055058595,0.02283041,-0.053657571,0.081966316,-0.052562691,0.078697749,-0.913824881,-1.378128413,0.792041702,1.379230711,-2.632302968,-3.191543633,-2.712428177,-2.548547668,-2.600726822,-2.108268539,-3.389924856,-0.598454242 -4462,V258W,-0.029627458,-1.795899454,-1.775713506,-2.027164139,-2.404658216,0.050350679,0.036169487,-0.095424402,-0.094785987,-1.659752058,-1.93204685,-1.813958591,-1.73746842,-2.289161657,-1.765166621,-2.337098252,-2.472218179,0.040061397,-1.032369719,-10.02960909,-10.94091104,-9.656170303,-10.88805606,-10.44906258,-8.213845451,-8.869157542,-8.970034247 -4463,V258Y,-0.015492551,-0.717968386,-2.153804852,-2.245876105,-2.568797946,0.011824267,0.02570579,-0.056690892,0.050936356,-0.478861916,-0.957074856,-1.943053287,-2.364556417,-2.020316345,-2.471435864,-2.068252939,-3.069342953,4.08046577,2.19523157,-9.03190869,-10.14858277,-8.705362373,-10.49649725,-8.720519714,-7.088581345,-6.236381338,-3.445007873 -4464,I259A,0.016237689,-0.025813888,0.035557073,-1.026115602,-2.396194248,-0.032112264,0.005434207,0.02704117,0.011290742,-0.027770568,-0.023857208,-0.011335246,0.082449391,-0.433967039,-1.618264164,-2.050303389,-2.742085107,1.592846441,1.359157264,-7.972255014,-7.383323166,-8.911997299,-7.047999474,-7.844159233,-8.673795898,-3.417644996,-0.578165791 -4465,I259C,-0.006617213,-0.068404834,0.066826207,-0.035567417,-0.834334283,-0.022547674,-0.006054812,-0.007179614,0.034801219,-0.09341334,-0.043396327,0.047171642,0.086480772,-0.004821698,-0.066313135,-0.452707915,-1.215960651,1.383714249,1.805431757,-10.46375344,-9.69413871,-11.56035831,-11.23857656,-9.833451538,-9.992242065,-6.090462107,-3.022607286 -4466,I259E,-0.019133861,-1.265967529,-2.088537371,-2.019912975,-2.540625964,0.004471863,-0.023127119,-0.015140603,-0.036222202,-0.901480592,-1.630454465,-2.157458693,-2.019616048,-2.225210477,-1.814615472,-2.801167666,-2.280084261,0.668318405,-0.577704193,-12.51036276,-12.0451253,-13.34469574,-13.00482675,-11.55085026,-12.60631576,-8.61243677,-5.3556558 -4467,I259D,0.040952266,-1.915802737,-2.418448303,-2.703221578,-2.877019385,-0.037897667,0.045847857,0.036056674,-0.132890139,-2.348850319,-1.482755154,-2.099678442,-2.737218163,-2.468460222,-2.937982934,-2.567296156,-3.186742613,-0.286260159,-1.204060364,-14.38683522,-13.67070865,-15.81508936,-14.95836974,-13.13573602,-14.35427232,-10.22716526,-9.272965999 -4468,I259G,-0.017523744,-0.658156103,-1.863252469,-2.206128201,-2.671910904,0.00344842,-0.021381534,-0.013665953,0.019773286,-0.375386435,-0.940925771,-1.940882643,-1.785622295,-2.173444675,-2.238811727,-2.483133975,-2.860687832,1.34474071,-0.030459264,-12.13163427,-11.57221709,-13.18489487,-12.425702,-11.33777472,-12.13758268,-7.175415298,-4.068156467 -4469,I259F,0.003265234,0.00100186,0.057359127,0.005161446,-1.458335429,-0.029165576,0.02166431,-0.015133843,0.082530252,-0.0442261,0.04622982,0.005373421,0.109344833,-0.042723675,0.053046567,-0.814426811,-2.102244047,0.862141721,1.409335207,-7.734231497,-6.144914345,-8.051635185,-8.606619965,-8.954379356,-6.913608635,-7.19455713,-2.815954569 -4470,I259H,0.015779556,-0.823558578,-1.971839223,-2.370234389,-2.845062192,0.019226564,0.011014653,0.020544459,0.018575698,-0.533099373,-1.114017783,-2.052318909,-1.891359537,-2.296161952,-2.444306826,-2.696027882,-2.994096501,1.260323391,-0.176947155,-14.33454303,-13.01536629,-15.57749876,-15.03004639,-13.5592801,-14.49052362,-10.19652198,-9.062989929 -4471,I259K,-0.028800403,-1.547613779,-2.426923178,-2.561181455,-2.584464264,-0.06389963,-0.065511431,0.007910626,-0.078777246,-1.703190943,-1.392036614,-2.232170317,-2.621676039,-2.299922101,-2.822440809,-2.398758035,-2.770170493,-0.193341628,-1.082616838,-13.30298466,-12.62842825,-14.78173351,-13.57881761,-11.75959104,-13.76635291,-10.22716526,-9.272965955 -4472,I259M,0.022019825,-0.039318208,0.090268359,0.046171534,-0.366921391,0.017065703,0.056467599,-0.012427949,0.018168941,-0.05885645,-0.019779966,0.013643172,0.166893546,0.007573937,0.08476913,-0.306105845,-0.427736936,1.090767595,1.724656547,-5.310280156,-4.773584381,-6.425236496,-5.665681709,-5.633668068,-4.053230125,-6.308466682,-2.913255139 -4473,I259L,-0.007462276,0.00025969,0.027529956,-0.00523087,-0.088470575,-0.033488206,-0.022345154,0.007420603,0.045298632,-0.034663887,0.035183267,-0.007804997,0.062864909,-0.000654333,-0.009807406,-0.059557038,-0.117384111,1.253372453,2.321033659,-4.09143688,-2.990283882,-3.860269012,-5.243272858,-4.49118837,-3.87217028,-5.654433568,-1.619550644 -4474,I259N,0.049565474,-0.446270615,-1.96368322,-2.336502125,-2.66081493,0.063155768,0.075020863,0.024110085,0.036559061,-0.291945468,-0.600595761,-1.398161249,-2.52920519,-1.943034288,-2.729969961,-2.342900218,-2.978729641,3.574936444,1.959471003,-13.59589029,-12.92848701,-15.28806849,-13.88114085,-12.54921775,-13.33253734,-10.20928784,-9.184640344 -4475,I259Q,-0.030910939,-0.765320741,-2.018267482,-2.336514152,-2.899387584,-0.047117267,-0.041499923,-0.020321955,0.027822568,-0.466655821,-1.06398566,-2.062581984,-1.973952979,-2.130333768,-2.542694535,-2.530199698,-3.268575469,1.1125292,-0.209410727,-13.34428223,-12.82746543,-14.51832676,-13.91905456,-11.63315151,-13.8234129,-10.22716526,-9.272965952 -4476,I259P,-0.012771635,-1.77422703,-2.02491538,-2.428808238,-2.666364125,-0.003627724,-0.012731263,-0.012812006,-0.026470635,-1.943986586,-1.604467473,-2.162176127,-1.887654633,-2.292075818,-2.565540658,-2.726703854,-2.606024395,-0.880638875,-1.125437005,-13.94016473,-13.3734584,-15.22898036,-13.999257,-13.31833646,-13.78079144,-10.16346523,-8.936462429 -4477,I259S,-0.030388726,-0.076420429,-1.323544954,-2.160851448,-2.874239878,-0.014004822,-0.035433681,-0.02534377,-0.002783283,-0.016915456,-0.135925401,-1.118338709,-1.528751198,-2.109075309,-2.212627587,-2.508941238,-3.239538517,2.164728183,0.80986155,-9.955215167,-9.07216584,-11.04022029,-9.507480316,-9.539356903,-10.61685249,-5.969520613,-2.957840153 -4478,I259R,-0.020776963,-1.805524139,-2.116374213,-2.305927346,-2.495483678,-0.028358604,-0.021506404,-0.020047521,-0.043276512,-1.859276862,-1.751771415,-2.212164976,-2.02058345,-2.154978024,-2.456876667,-2.855873949,-2.135093407,-0.422125406,-1.114607254,-13.9684934,-13.35059718,-15.03024307,-14.5024239,-12.48565578,-14.47354706,-10.22716526,-9.272965952 -4479,I259T,-0.004504223,-0.027410059,0.023035262,-0.924139011,-1.997076674,-0.072420049,-0.013055454,0.004047008,0.00425137,-0.066286704,0.011466586,-0.03593069,0.082001213,-0.543672692,-1.304605329,-1.792270946,-2.201882401,1.558161435,1.429467917,-8.359448515,-8.56974353,-8.885516693,-7.953182541,-8.231493843,-8.157305969,-6.154932114,-2.617424452 -4480,I259W,-0.011617459,-0.011031158,-0.110209634,-1.536861215,-2.428120809,0.087064809,0.0086076,-0.031842518,0.036868575,-0.068064452,0.046002136,-0.053706302,-0.166712966,-1.263221316,-1.810501113,-2.282876004,-2.573365614,2.186508487,1.373218162,-13.12530649,-11.96974539,-13.97483553,-14.01323229,-13.08973362,-12.57898563,-10.22716526,-9.272965964 -4481,I259V,0.010544808,-0.005507439,0.040323085,-0.010872965,-0.020923763,0.00767212,0.009911523,0.011178093,0.00353074,-0.040082554,0.029067676,-0.004547454,0.085193623,0.006298475,-0.028044405,-0.046852965,0.005005439,1.300126048,2.636287204,-3.188228323,-3.369792336,-3.20571669,-3.080606033,-3.761401352,-2.523625206,-4.012931183,0.821965532 -4482,I259Y,0.020915231,0.00499355,0.058215089,-1.053517242,-2.403888322,0.033069463,0.056403079,-0.014572618,0.040681302,-0.079027541,0.089014641,-0.03327005,0.149700228,-0.374728703,-1.73230578,-2.086348494,-2.721428149,1.682577698,1.383335251,-11.99125661,-10.65569012,-13.02053458,-12.81673318,-12.16834022,-11.29498497,-8.86039809,-5.638871063 -4483,Y260A,-0.072282856,-0.017491337,-0.491232523,-1.71675373,-2.509598383,0.02361869,-0.094517257,-0.050048455,-0.044963468,-0.004654585,-0.030328088,-0.186958185,-0.79550686,-1.418210984,-2.015296475,-2.335708158,-2.683488607,1.231829444,0.78015655,-11.59599843,-10.12865441,-14.36169131,-9.556068932,-10.91927251,-13.014305,-6.66756516,-2.881714221 -4484,Y260C,-0.05966662,-0.055302441,-0.039341381,-1.00987561,-2.041769272,-0.014622301,-0.101314369,-0.01801887,-0.032125486,-0.049684178,-0.060920703,0.009809075,-0.088491837,-0.458684929,-1.561066291,-1.824405017,-2.259133527,1.693213386,1.427454004,-11.7492586,-12.12689021,-14.02378864,-8.786730064,-10.64636112,-13.16252297,-6.780323556,-2.263819062 -4485,Y260E,-0.04437061,-0.940282026,-1.981043507,-2.418726626,-2.560872172,0.001907722,-0.049135613,-0.039605606,0.032999133,-0.587713537,-1.292850514,-2.067701743,-1.89438527,-2.590238389,-2.247214862,-2.981765741,-2.139978603,0.887276786,-0.389100913,-13.23631614,-12.32415756,-15.15885511,-11.69851585,-12.66832561,-14.33172655,-9.516601846,-7.418804548 -4486,Y260D,-0.123591388,-1.372445532,-1.870817811,-2.46451362,-3.17182605,-0.012991233,-0.165387036,-0.08179574,-0.085193717,-1.10086917,-1.644021894,-1.893625775,-1.848009846,-2.160889916,-2.768137323,-2.728508527,-3.615143573,3.616910363,1.454322003,-14.62173883,-13.48005814,-18.2033886,-11.87273505,-14.49698966,-15.05552271,-9.120452536,-6.791117909 -4487,Y260G,-0.048297163,-0.96498148,-2.049906106,-2.228508013,-2.596437133,-0.010718826,-0.090411006,-0.006183319,-0.00589641,-0.628918938,-1.301044022,-2.08678728,-2.013024932,-2.169991233,-2.287024792,-2.324157668,-2.868716598,1.25664558,-0.242461059,-13.51905942,-11.93668503,-16.35935231,-11.12224606,-12.70877942,-15.46823428,-7.800460091,-4.676206214 -4488,Y260F,-0.147395519,-0.033552122,-0.040019108,-0.038130585,-0.067153261,-0.060307736,-0.07492516,-0.219865878,-0.072429585,-0.029393473,-0.03771077,-0.024596476,-0.05544174,0.031946593,-0.108207762,-0.021114571,-0.11319195,1.181133305,2.500025061,-3.668141696,-2.41479084,-6.398801376,-3.003712791,-3.565915451,-2.957488022,-3.456446068,-0.030094309 -4489,Y260I,-0.0953303,-0.063479426,-0.119149612,-0.06770156,-0.888012503,-0.019439605,-0.039666817,-0.150993783,-0.05307656,-0.104034819,-0.022924033,-0.168995093,-0.069304131,-0.121503214,-0.013899905,-0.458672903,-1.317352102,2.013666612,2.275029068,-12.99707597,-11.17831162,-18.01060628,-11.05781602,-12.68474937,-12.05389654,-7.316876963,-3.08144686 -4490,Y260H,-0.041080456,-0.184792904,-1.924316066,-2.319041871,-2.685733682,-0.030575233,-0.069174168,-0.012986743,-0.075801374,0.029392028,-0.398977835,-1.692783502,-2.155848629,-2.340258885,-2.297824856,-2.430756241,-2.940711123,0.526761823,-0.000565446,-8.99707758,-8.240213318,-10.02224867,-7.580214317,-9.633378876,-9.509332718,-7.963764771,-5.437550076 -4491,Y260K,-0.011171246,-0.788743113,-2.703249595,-2.34540041,-2.964667211,-0.141860836,-0.038013281,0.015670789,-0.057196512,-0.486506763,-1.090979463,-2.499371456,-2.907127733,-2.544786847,-2.146013973,-2.635284203,-3.294050218,0.436570016,-0.483639125,-13.38885349,-12.64384152,-16.34126991,-11.46899885,-13.59174181,-12.89841539,-10.00794245,-9.205784858 -4492,Y260M,-0.073449131,0.029482713,-0.004989957,0.023379691,-0.00915987,-0.113022743,-0.049594483,-0.097303778,-0.038776756,0.010271093,0.048694332,-0.02460752,0.014627606,0.02816632,0.018593062,-0.020474113,0.002154373,1.518083569,2.753374319,-9.783943736,-6.988291771,-14.29872241,-8.284512238,-9.152203392,-10.19598887,-4.908856009,-0.647399082 -4493,Y260L,-0.084914403,-0.020775004,-0.031811312,-0.000948022,-0.046084325,-0.07697824,-0.03523412,-0.134594686,-0.015423212,-0.007878761,-0.033671246,-0.02169377,-0.041928853,0.027425488,-0.029321531,-0.016441901,-0.075726749,1.121957387,2.500446185,-9.394937222,-6.149372253,-13.74204079,-8.5809543,-8.757868309,-9.744450455,-4.559047713,0.155257905 -4494,Y260N,-0.052565001,-0.368327012,-1.767612923,-1.9237781,-2.781605528,-0.003444473,-0.05452636,-0.050603642,0.040031585,-0.050388433,-0.686265591,-1.463801518,-2.071424327,-1.509216909,-2.338339291,-2.502804252,-3.060406804,3.405671808,1.921040951,-12.15684767,-11.76765697,-14.97679545,-9.590075668,-12.25124696,-12.19846331,-8.659608795,-6.388198237 -4495,Y260Q,-0.061500258,-0.022123325,-0.687588545,-1.979071578,-2.950520896,-0.036250583,-0.070835246,-0.052165269,-0.058462378,-0.027300959,-0.01694569,-0.325207542,-1.049969547,-1.695134025,-2.26300913,-2.438843895,-3.462197897,1.528841336,0.78963823,-11.142638,-10.66141721,-13.7358939,-9.652681763,-11.50468201,-10.15851513,-6.252297468,-4.236982022 -4496,Y260P,-0.058138034,-1.562253741,-2.064005811,-2.484307877,-2.515529048,0.009588218,-0.083673189,-0.032602879,-0.110849944,-1.652062961,-1.47244452,-1.98888761,-2.139124011,-2.636362993,-2.332252761,-2.550769089,-2.480289006,-0.043995955,-1.069313228,-14.82202447,-13.40235117,-17.79424993,-12.69574359,-14.48232264,-15.73545503,-10.00794245,-9.205784818 -4497,Y260S,-0.061731257,-0.029667082,-0.371459414,-1.789700372,-2.724576282,-0.073910141,-0.094557031,-0.028905483,-0.027906979,-0.001603376,-0.057730787,-0.108566783,-0.634352045,-1.436871945,-2.142528799,-2.216579467,-3.232573097,1.36834592,0.816332658,-9.693370224,-9.086387611,-12.71046552,-6.902050911,-8.637379272,-11.1305678,-6.70220929,-4.858032158 -4498,Y260R,-0.077928066,-1.616122091,-2.223777567,-2.225838455,-2.746634556,-0.058082476,-0.131275459,-0.024580672,-0.113285067,-1.601567206,-1.630676976,-2.372047416,-2.075507717,-2.241371549,-2.21030536,-2.456807641,-3.03646147,-0.032484545,-1.047981936,-14.48581558,-14.71467525,-18.30357701,-12.74436176,-14.30432349,-12.36214037,-9.809122211,-8.256829066 -4499,Y260T,-0.103093154,-0.054476467,-0.079361717,-1.051979135,-2.274308919,-0.014279584,-0.118310001,-0.087876307,-0.040105668,-0.019997939,-0.088954995,-0.080717242,-0.078006192,-0.565465328,-1.538492942,-1.79514186,-2.753475977,1.886440236,1.501916786,-10.92885226,-9.803135475,-13.51393238,-8.700574722,-10.40580414,-12.22081456,-6.795837818,-3.607504258 -4500,Y260W,-0.038686044,-0.047330685,-1.102839299,-2.14392802,-3.221421795,-0.059147698,-0.082652529,0.005280441,-0.073754459,-0.048892185,-0.045769184,-0.728596586,-1.477082011,-1.96200246,-2.325853579,-3.131681062,-3.311162527,1.921668819,0.813342199,-10.09501888,-10.22924792,-12.01098456,-9.139470497,-9.063654968,-10.03173646,-8.290860154,-6.126662747 -4501,Y260V,-0.122977346,-0.023628067,-0.031510371,-0.02200698,-1.413474729,-0.031581751,-0.059360219,-0.186594472,-0.027461959,-0.001572908,-0.045683225,-0.016797357,-0.046223385,0.000822253,-0.044836213,-1.034640295,-1.792309162,0.821454006,1.368770616,-13.04895522,-11.49013168,-17.54958967,-10.59640195,-11.73966512,-13.86898766,-7.031348343,-3.835548688 -4502,T261A,-0.014285979,0.031585043,0.00022499,-0.007997066,-0.117114405,0.042901361,-0.035555301,0.006983343,0.054626727,0.014025895,0.049144191,0.066962824,-0.066512844,0.020116008,-0.036110139,-0.092204458,-0.142024352,1.133841839,2.235642028,-3.512026106,-3.351412773,-4.563860886,-3.806197578,-2.26745713,-3.571202164,-4.494667495,-2.403969423 -4503,T261C,0.003694396,-0.031294852,-0.030040809,0.00424798,-0.065010882,0.02695247,0.023088591,-0.0156998,-0.015594038,-0.046863387,-0.015726317,0.038421176,-0.098502793,0.033509274,-0.025013314,-0.031333519,-0.098688244,1.350152086,2.616512074,-4.512133832,-3.203469093,-5.500652733,-8.244894646,-0.421696716,-5.189955971,-3.790493301,-2.872153303 -4504,T261E,0.039859412,-0.059440648,-0.081492935,-0.157045469,-1.447797775,-0.191770437,0.07504148,0.004677344,-0.023980377,-0.060003654,-0.058877641,0.008482969,-0.171468838,-0.034370996,-0.279719942,-1.343887859,-1.551707691,0.637290785,1.325152765,-7.557720436,-6.364607559,-8.5873759,-8.518826386,-6.366083099,-7.951709236,-5.354834656,-4.721116579 -4505,T261D,0.030741786,-0.155714523,-0.506678739,-0.706035484,-1.133929996,0.01022771,0.023531156,0.037952415,0.370471304,0.232614481,-0.544043526,-0.180972252,-0.832385225,-0.287808527,-1.124262441,-0.678485203,-1.589374788,2.262126935,2.292978863,-9.533139777,-9.107868423,-11.84589209,-9.880145271,-7.193527199,-9.6382659,-6.443163018,-6.324624818 -4506,T261G,-0.036664943,-0.001234837,-0.017182419,-1.322676215,-2.325524065,-0.051397463,-0.025384518,-0.047945367,0.012822198,-0.012291504,0.009821831,0.026859672,-0.06122451,-0.884312437,-1.761039993,-2.07271327,-2.578334859,2.067978617,1.46461415,-7.12929641,-6.566768791,-7.364131767,-8.571052032,-5.342426453,-7.802103004,-5.648175894,-4.187743361 -4507,T261F,-0.044521289,-0.012889473,-0.051048655,-0.037952887,-0.069969718,-0.006021858,-0.020356021,-0.068686557,-0.011310625,-0.003476786,-0.02230216,0.004186028,-0.106283337,0.018393444,-0.094299218,-0.023409322,-0.116530114,1.181659282,2.445348648,-5.117860339,-5.613324997,-6.018670532,-6.735234833,-1.785940346,-5.436130989,-3.658515766,-2.368530593 -4508,T261I,-0.030540215,0.0000234,-0.038620157,0.008888233,0.027491917,0.088767939,-0.035476038,-0.025604391,0.051343086,0.012744297,-0.012697487,-0.003989522,-0.073250791,0.026188633,-0.008412167,0.044644207,0.010339627,1.090621435,2.630263657,3.277041536,3.323406761,2.516452042,3.247402481,5.873855392,1.424091003,-0.522038907,-1.292592916 -4509,T261H,-0.001769028,-0.003583015,-0.020217945,0.037207396,-1.388134769,-0.063739223,0.015760414,-0.01929847,-0.03819257,0.008898598,-0.016064628,0.002970544,-0.043406433,0.09050342,-0.016088629,-1.347961745,-1.428307792,0.784739269,1.336927847,-6.864714278,-4.479100113,-8.002787735,-9.924378792,-5.260623466,-6.656681282,-4.443497762,-4.420776551 -4510,T261K,-0.044051031,-0.032426188,-0.113977936,-1.084118095,-1.583893884,-0.076007511,-0.002373874,-0.085728188,0.101040294,-0.008761513,-0.056090862,0.011139213,-0.239095085,-0.836648627,-1.331587563,-1.085852128,-2.081935639,3.686238482,3.283722507,-7.720299409,-7.072134308,-8.917007988,-8.709692734,-5.799580917,-8.1030811,-7.646808044,-9.277853799 -4511,T261M,-0.020998583,0.053144428,-0.022079583,0.010826222,0.039460117,-0.054975711,-0.010452412,-0.031544754,-0.040520272,0.072413817,0.033875038,0.02842619,-0.072585356,0.053755015,-0.032102571,0.06902793,0.009892303,1.151352105,2.927102096,2.532973883,2.722586792,1.146748825,2.858327263,5.294254417,0.642952118,-1.094487602,-3.198127944 -4512,T261L,-0.031351776,-0.006616761,-0.044324127,0.002887896,0.020071381,0.162113046,-0.036644419,-0.026059133,-0.015112181,-0.002413708,-0.010819814,0.007891318,-0.096539571,0.019570545,-0.013794754,0.028627251,0.01151551,1.120269569,2.720637091,3.645090091,3.570366051,2.10985791,4.08937088,6.755315979,1.700539635,0.046950566,-0.951933762 -4513,T261N,-0.036233933,0.001601363,-0.038955767,-1.349785869,-2.063688368,-0.051540832,-0.005109518,-0.067358347,0.029436146,0.014159295,-0.01095657,-0.010365114,-0.06754642,-0.929337138,-1.770234599,-1.67018104,-2.457195696,2.655456319,2.012494189,-7.168128453,-6.639373268,-8.313595024,-8.935227074,-5.513446579,-6.43900032,-5.202182493,-4.41433678 -4514,T261Q,-0.026865226,-0.00275608,-0.021137748,0.006407391,-0.734585906,-0.014863337,0.009702112,-0.063432564,0.014772212,-0.031777404,0.026265245,0.021705917,-0.063981412,0.025387375,-0.012572594,-0.510362873,-0.958808939,1.169928994,1.626378942,-4.767972841,-4.741293152,-5.357062706,-5.36631485,-2.724142738,-5.651050758,-5.142377456,-5.646783214 -4515,T261P,-0.051729661,-1.209048012,-1.478391474,-1.705794403,-2.009491872,-0.071243059,-0.025604356,-0.077854965,-0.052075845,-1.065496578,-1.352599445,-1.275320625,-1.681462322,-1.4214102,-1.990178606,-1.537679359,-2.481304385,4.366353343,2.898416335,-8.584564052,-8.154872025,-9.921804855,-9.396705505,-6.840224373,-8.609213501,-7.646808044,-9.277853799 -4516,T261S,-0.04153625,0.005249399,-0.027775818,-0.012569236,-0.152342955,-0.039757827,-0.055492548,-0.027579951,0.01807994,0.007255633,0.003243164,0.042052023,-0.097603659,0.030696151,-0.055834623,-0.107695851,-0.196990058,1.43893518,2.435965157,-3.696815382,-2.004771515,-4.224057846,-5.828063255,-2.619714195,-3.8074701,-3.299103984,-0.549150281 -4517,T261R,-0.047435105,-0.005331462,-0.227359064,-1.660180167,-2.221617153,-0.061305822,-0.029643976,-0.065226234,0.038482869,-0.002044636,-0.008618288,-0.037572142,-0.417145986,-1.340992737,-1.979367597,-1.772584238,-2.670650068,3.314483106,2.457911933,-6.857941971,-8.071361259,-7.635661728,-7.135526718,-5.219129875,-6.228030273,-6.381694369,-6.779492967 -4518,T261W,-0.03827179,-0.021851206,-0.05495697,-1.328809776,-2.401692131,-0.067239209,-0.003730159,-0.07281342,0.042824127,-0.04573751,0.002035099,-0.036264641,-0.073649298,-0.964409084,-1.693210467,-2.131942539,-2.671441722,2.083651164,1.438073243,-7.323701797,-5.932525757,-9.593874298,-8.626766487,-5.153449615,-7.31189283,-5.176521596,-5.092067627 -4519,T261V,0.004266721,0.013900202,0.020052301,0.032847247,0.010115662,0.091204147,-0.005128185,0.013661626,0.025662384,0.011315133,0.016485271,0.071308852,-0.03120425,0.052959044,0.012735449,0.014852278,0.005379046,1.114724013,2.619711616,1.951414241,1.812619408,1.785274994,1.579528458,4.105285858,0.474362488,-1.656496313,-0.631351952 -4520,T261Y,-0.054803606,0.016493944,0.018235119,-0.371292389,-1.629958204,-0.070761152,-0.001800183,-0.107807028,0.048366282,0.070449134,-0.037461247,0.087809976,-0.051339739,0.018195138,-0.760779915,-1.337376576,-1.922539831,0.561859367,1.320689651,-6.528076045,-4.239351334,-9.035394753,-9.587568748,-3.151636696,-6.626428696,-3.424101368,-2.205381852 -4521,T262A,0.011848743,-0.024133379,0.012453365,-0.027588368,-0.184603363,0.019847643,0.014933162,0.008764323,-0.006035782,-0.004324182,-0.043942575,-0.037257789,0.062164519,-0.025105444,-0.030071291,-0.165429824,-0.203776902,1.283816744,2.066464124,-4.149901099,-3.927634903,-4.961742622,-4.079368713,-4.302227959,-3.478531296,-4.667009366,-1.24072319 -4522,T262C,-0.020163147,-0.023859035,0.004085288,-0.049625658,-0.499777363,-0.012773316,-0.008002867,-0.032323426,-0.041023277,0.000956118,-0.048674187,-0.022639137,0.030809713,-0.018919703,-0.080331613,-0.314724307,-0.684830418,1.350775313,1.910469959,-9.45830834,-7.804427902,-10.63278175,-8.962347694,-10.0022037,-9.889780655,-8.084541927,-4.201648578 -4523,T262E,0.00072749,-0.009113868,-0.005898192,-0.032555413,-0.342937209,0.015745521,0.006154741,-0.004699762,0.074728013,0.010249704,-0.028477439,-0.099266564,0.087470181,-0.035297089,-0.029813737,-0.319983559,-0.365890858,2.052106022,2.500303776,-9.382194424,-9.321837936,-10.24132143,-9.057890686,-8.871168465,-9.418753601,-4.865470376,-1.038974493 -4524,T262D,0.016751967,-0.007382977,-0.004817269,-0.029182469,-1.492670549,-0.036967075,0.034264989,-0.000761056,-0.043957962,-0.001648843,-0.013117111,-0.047268925,0.037634388,0.01860307,-0.076968008,-1.465346758,-1.51999434,0.458796644,1.310537506,-8.83371104,-7.595291199,-10.97392264,-8.188586166,-8.172025635,-9.238729561,-6.502219107,-1.264493919 -4525,T262G,-0.007282321,-0.014294871,-0.009217002,-0.128957456,-1.73144799,-0.008249249,0.001195197,-0.015759839,-0.031805125,-0.006128566,-0.022461176,-0.050138491,0.031704487,-0.015356322,-0.242558589,-1.642255695,-1.820640284,0.444685786,1.304532869,-6.792878932,-8.333815956,-5.812388695,-7.99049337,-6.138011841,-5.689684799,-5.868810379,-2.220503434 -4526,T262F,0.022710498,-0.01090472,0.022961332,-0.014943009,-0.92448673,0.005847722,0.043344693,0.002076302,-0.022259482,-0.002937333,-0.018872106,-0.042359425,0.088282089,-0.040471131,0.010585113,-0.689434851,-1.159538608,0.97504803,1.47039466,-10.66048442,-9.713035187,-12.0591229,-10.3340136,-10.50092654,-10.69532387,-7.54727813,-4.48376697 -4527,T262I,-0.017412538,-0.025216039,-0.046369305,-0.093185835,-0.328180078,-0.001555474,0.010087077,-0.044912152,0.100168479,-0.014565015,-0.035867063,-0.145687012,0.052948403,-0.114529912,-0.071841758,-0.346146936,-0.310213219,1.482670916,1.934373749,-8.338454524,-7.365131081,-10.06267982,-7.511862595,-7.76326767,-8.989331451,-7.920299201,-4.088838486 -4528,T262H,0.014487176,-0.016890748,0.001718988,-0.041867014,-0.056949167,-0.032519822,0.01460496,0.014369392,-0.006481472,-0.018671361,-0.015110134,-0.054226783,0.057664758,-0.041690111,-0.042043917,-0.066100426,-0.047797907,1.417506744,2.441899588,-7.848566275,-6.100214401,-8.972610481,-7.381778137,-7.55733622,-9.230892136,-6.591762974,-2.413720546 -4529,T262K,0.007479157,-0.046787776,-0.005910112,-0.006335176,-0.288236162,0.063129212,0.00734704,0.007611274,0.034006173,-0.027156836,-0.066418715,-0.084971802,0.073151579,0.007926739,-0.02059709,-0.324294086,-0.252178238,1.461701836,1.98750196,-7.050550815,-6.584538322,-8.319453995,-6.808058456,-5.633666267,-7.907037033,-5.039956949,-0.631447024 -4530,T262M,-0.001117864,-0.01789127,0.006968232,-0.014061376,-0.303880306,0.062160104,0.006124019,-0.008359747,0.102887463,0.010101623,-0.045884162,-0.026005626,0.03994209,0.008258169,-0.036380921,-0.201997467,-0.405763144,1.208418751,1.961086861,-7.150220375,-6.119265091,-8.725239349,-7.257596596,-6.857623413,-6.791377426,-6.920505202,-2.853890571 -4531,T262L,-0.012137824,-0.013693745,-0.001172104,-0.042542135,-1.271330923,0.058934492,0.025744285,-0.050019933,-0.019782714,0.004186877,-0.031574366,-0.041268683,0.038924476,-0.042462224,-0.042622046,-1.038867991,-1.503793855,0.830296741,1.369545177,-9.165628055,-7.42555542,-11.23355715,-8.785360374,-8.477951256,-9.905716072,-7.410045333,-3.994255027 -4532,T262N,-0.009044304,-0.027645316,-0.036746265,-0.072471817,-0.252092626,0.026403524,-0.019764052,0.001675445,0.043912555,-0.038892363,-0.016398268,-0.08163875,0.008146221,-0.030784892,-0.114158742,-0.199402443,-0.304782809,1.661032361,2.346463409,-7.177688963,-6.340127289,-6.210756821,-6.88868119,-7.839890663,-8.608988853,-5.827978188,-1.704431184 -4533,T262Q,0.01593764,-0.012038894,-0.022007389,-0.019957494,-0.127158583,-0.003303514,0.052434839,-0.020559559,0.06829655,-0.000535552,-0.023542235,-0.082787172,0.038772395,-0.003830992,-0.036083995,-0.164170066,-0.090147099,1.385678329,2.187890627,-8.625826591,-8.421038246,-8.844362381,-8.861117264,-7.961960228,-9.040654839,-6.700774634,-1.788018251 -4534,T262P,-0.024020357,-0.297829203,-1.51467981,-2.012471149,-2.535717236,0.035346496,0.013757778,-0.061798491,-0.031593282,-0.083797022,-0.511861383,-1.439142351,-1.590217269,-1.947821214,-2.077121084,-2.375723948,-2.695710524,3.650370446,2.066779367,-11.35265139,-10.79673875,-12.04243652,-10.6154052,-11.85809808,-11.45057841,-9.766513152,-6.437760534 -4535,T262S,0.031549021,-0.011046225,0.006152354,-0.026530358,-0.076728028,0.000049,0.049801628,0.013296414,-0.027476615,0.002780423,-0.024872873,-0.046428747,0.058733455,-0.041845278,-0.011215437,-0.087966134,-0.065489922,1.428796799,2.386921926,-4.853970601,-3.736562202,-3.930258064,-4.784720444,-5.905135735,-5.913176559,-4.072834797,-0.711967113 -4536,T262R,-0.002055447,-0.021307677,0.00906787,-0.039143154,-0.770570643,0.046110181,0.018395276,-0.022506169,-0.040772123,-0.006245214,-0.03637014,-0.050130398,0.068266138,-0.0311096,-0.047176708,-0.557937639,-0.983203647,1.014552155,1.527388546,-6.536943355,-5.274847351,-7.103636848,-7.554369949,-5.930428307,-6.821434319,-4.450871755,-0.554171596 -4537,T262W,-0.002091769,-0.022006907,0.018885843,-0.026839077,-0.543352313,0.052812231,0.023180218,-0.027363756,-0.011496702,-0.010330231,-0.033683582,-0.033749678,0.071521364,-0.032146571,-0.021531582,-0.365837275,-0.720867351,1.829533058,2.244154105,-10.23424948,-9.047029854,-11.23502734,-9.491521812,-10.2028396,-11.1948288,-6.712109229,-3.728267542 -4538,T262V,0.004094788,-0.014804794,0.002196313,-0.040168926,-0.078381564,-0.021448175,-0.008229329,0.016418905,0.037269626,0.007274023,-0.03688361,-0.04080321,0.045195836,-0.024370973,-0.055966878,-0.060957609,-0.095805518,1.237246678,2.34953621,-6.610072385,-5.686063721,-8.810518425,-5.867086395,-6.030935989,-6.655757393,-6.452765513,-3.090568951 -4539,T262Y,0.042052064,0.005950653,0.005186751,-0.029583539,-0.185138764,-0.045929654,0.0280406,0.056063528,-0.046632903,-0.005201194,0.0171025,-0.057595946,0.067969448,-0.041006593,-0.018160485,-0.158060254,-0.212217273,1.466024791,2.187192313,-10.03465033,-8.536677582,-11.273066,-9.232341331,-10.0704697,-11.06069702,-7.125847021,-3.556608807 -4540,G263A,-0.028484373,-0.009941599,-0.03760421,-0.020299826,-0.974024595,0.167584776,-0.043938427,-0.013030318,0.043044517,-0.003285511,-0.016597687,-0.016808879,-0.058399541,-0.014968249,-0.025631403,-0.789211158,-1.158838032,0.736184734,1.386433467,-4.209983147,-4.137628609,-5.080710732,-2.736112312,-3.489566475,-5.605897606,-3.790887984,-1.127860543 -4541,G263C,-0.09720748,-0.007663335,-0.040404932,0.000712993,-1.002343849,0.178624248,-0.106901457,-0.087513503,0.06847394,0.044535054,-0.059861723,0.005176643,-0.085986507,0.03210325,-0.030677265,-0.76794235,-1.236745348,0.455173506,1.352391266,-8.766781047,-8.119428711,-9.239565605,-8.50408535,-8.4178078,-9.553017769,-6.22969773,-4.825425468 -4542,G263E,-0.049265962,0.002878942,-0.033242708,0.007960836,-0.511025386,-0.017357619,-0.035118434,-0.063413489,0.091604503,-0.002302086,0.008059969,-0.003931559,-0.062553857,0.033056363,-0.017134691,-0.369892518,-0.652158253,1.763906751,2.207113698,0.397737476,0.318015404,0.2295905,0.168523697,0.792881248,0.479676529,-1.425394296,-0.876365216 -4543,G263D,-0.020420396,-0.007605785,-0.022483863,-0.017287217,-0.225119598,-0.010112809,-0.038503139,-0.002337652,0.014340176,0.008820762,-0.024032332,-0.01114213,-0.033825595,0.003138529,-0.037712963,-0.174608906,-0.27563029,1.31493548,2.079034833,-0.666998534,-0.8245933,-0.278123787,-1.371158531,-0.120494392,-0.740622658,-1.961873061,-0.289909593 -4544,G263F,-0.034010893,0.012810676,-0.03338027,-0.310949111,-1.960090392,0.038793158,-0.037540464,-0.030481321,0.021625596,0.035135496,-0.009514144,-0.02190677,-0.04485377,-0.037441296,-0.584456926,-1.895854692,-2.024326091,0.780512767,1.304420302,-10.43263229,-8.653844391,-10.09994276,-9.478297264,-12.10291817,-11.82815884,-5.882785527,-4.213475428 -4545,G263I,-0.084415327,-0.015492916,-0.096301432,-1.404872239,-2.225456764,0.159107511,-0.121182521,-0.047648133,0.110452586,-0.028735704,-0.002250127,-0.021461758,-0.171141106,-0.852437983,-1.957306495,-1.997621927,-2.453291601,2.058817333,1.485659766,-8.503029451,-9.624964592,-10.63015932,-4.759716904,-8.813308189,-8.686998253,-5.030412853,-3.764095653 -4546,G263H,-0.003676049,0.002963259,-0.05831865,-0.020381756,-1.588938653,-0.032093197,0.002237209,-0.009589307,0.057746236,-0.006766543,0.01269306,-0.071361794,-0.045275505,0.021275907,-0.062039418,-1.46579636,-1.712080945,0.675564488,1.321332518,-5.087114111,-3.446075684,-4.378520767,-7.17128569,-5.744555809,-4.695132607,-4.77117466,-2.152634703 -4547,G263K,-0.101623179,0.011394885,-0.03864455,-0.225053672,-2.214016011,0.038549788,-0.114286995,-0.088959362,0.068048738,0.045046949,-0.022257179,0.02070558,-0.09799468,0.049669554,-0.499776898,-1.579069755,-2.848962267,0.719369325,1.317873495,-3.900828882,-4.294043518,-2.230540115,-5.191002502,-4.113692352,-3.674865921,-4.251569175,-0.977249284 -4548,G263M,-0.010839136,-0.011102727,-0.029771907,-0.00480984,-0.852062617,0.13905444,0.002441457,-0.024119729,-0.016322493,-0.022860875,0.000655422,-0.026517464,-0.033026349,-0.006758833,-0.002860846,-0.719471848,-0.984653386,0.713026623,1.394110438,-7.920160538,-8.531454437,-9.364031822,-5.402266441,-8.064323616,-8.238726372,-4.858404665,-3.581141265 -4549,G263L,-0.03898103,-0.007329136,-0.031712066,0.008488046,-1.341277354,0.040537604,-0.042065955,-0.035896104,0.135573327,-0.022400211,0.007741939,-0.029132635,-0.034291496,0.031334506,-0.014358414,-1.043342157,-1.639212551,0.725923805,1.354505673,-7.5211431,-8.040713402,-9.767653038,-4.700108208,-7.106046539,-7.991194313,-5.033801711,-3.368756632 -4550,G263N,-0.019561347,-0.023802695,-0.042058324,-0.045793843,-0.200660416,0.054905658,-0.048194486,0.009071792,0.072664025,0.008325036,-0.055930426,0.010526655,-0.094643302,-0.023570621,-0.068017065,-0.122744207,-0.278576624,1.330674272,2.241012084,-2.263897566,-2.020483727,-1.686061462,-4.323045563,-0.837668716,-2.452228363,-2.431608272,-0.631879314 -4551,G263Q,-0.026182039,0.017507364,-0.043068963,-0.013681903,-0.622310764,0.058323691,-0.022008872,-0.030355205,0.10121193,0.006632511,0.028382216,-0.028713229,-0.057424697,-0.00215089,-0.025212916,-0.481254046,-0.763367482,1.049610639,1.586039056,-0.564383199,-0.537182617,0.054457314,-1.482110336,-0.373515274,-0.483565079,-1.684251106,-0.924955861 -4552,G263P,-0.00459036,0.005873155,-0.004649849,-0.551592643,-1.844063311,0.450544561,-0.010751444,0.001570724,0.114019707,-0.018682509,0.030428818,-0.017861795,0.008562098,-0.276522463,-0.826662823,-1.929750122,-1.758376499,1.363374546,1.346712472,-8.157052945,-8.992086411,-9.286438858,-7.435432564,-6.362035019,-8.709271873,-5.486985319,-2.82238441 -4553,G263S,-0.006300363,0.026546155,-0.009453026,0.014407684,-0.875088118,0.105867572,-0.023876409,0.011275683,0.057746236,0.040528029,0.012564281,0.033015748,-0.051921799,0.025559109,0.003256258,-0.669822755,-1.080353481,0.770700984,1.415085614,-5.800674097,-6.098882088,-5.922126778,-6.372987122,-4.443068314,-6.166306183,-4.156345555,-0.804264173 -4554,G263R,-0.040506006,-0.014057732,-0.031095534,-0.013480012,-1.505519016,0.159351058,-0.028646205,-0.052365806,0.065087235,0.004561747,-0.03267721,0.001907269,-0.064098336,0.036820093,-0.063780116,-1.429975474,-1.581062558,0.813330112,1.338763016,-3.943347664,-4.418225533,-2.797971504,-4.97258654,-3.751923141,-3.776031601,-3.896879717,-0.267572877 -4555,G263T,-0.055047609,-0.01787746,-0.048022982,-0.00601571,-1.717040964,0.188316339,-0.044851112,-0.065244106,0.100637604,0.028962216,-0.064717136,0.002765858,-0.098811821,0.07674677,-0.088778189,-1.556580821,-1.877501106,0.649581287,1.315842272,-6.714000049,-6.89831282,-6.979839302,-6.074209023,-5.763407745,-7.854231354,-4.15439875,-1.783626105 -4556,G263W,-0.020392319,0.001424568,-0.010465342,-0.652301284,-1.774132716,0.066486238,-0.008482811,-0.032301826,0.097309247,0.004992836,-0.0021437,-0.040005889,0.019075206,-0.238788791,-1.065813776,-1.71438442,-1.833881012,1.284154901,1.361569638,-9.306830794,-8.553217827,-8.801072502,-9.147896507,-10.83714317,-9.194823959,-6.250116515,-4.684196807 -4557,G263V,-0.035607663,0.017062146,-0.023432273,-1.004819675,-2.019069464,0.238626232,-0.010877864,-0.060337461,0.048494993,0.02872837,0.005395922,-0.025896241,-0.020968305,-0.622222598,-1.387416751,-1.921335111,-2.116803817,1.510401112,1.354256014,-8.244447395,-9.137481361,-10.09663457,-5.128026596,-8.190919762,-8.66917469,-5.210399462,-3.682303366 -4558,G263Y,-0.100701284,-0.031957268,-0.04519089,-0.406842491,-1.992529607,0.063608752,-0.066167832,-0.135234736,0.125769344,0.012054236,-0.075968772,-0.027206986,-0.063174794,-0.110706894,-0.702978088,-2.098822817,-1.886236397,0.697101523,1.288680203,-9.753437599,-7.218355423,-9.197708237,-10.58242555,-11.93368011,-9.835018677,-5.953697702,-2.977096242 -4559,S264A,0.014030355,0.00313289,-0.00468941,0.010981057,-0.157365839,0.101262187,-0.001750086,0.029810795,-0.039510244,0.007421411,-0.001155631,-0.00522176,-0.00415706,0.030654819,-0.008692706,-0.12782692,-0.186904757,1.501680679,2.468476538,-2.875053424,-3.880789421,-4.232066078,-1.700779808,-2.874291908,-1.687339905,-3.778166047,-0.444092331 -4560,S264C,-0.061231732,-0.020652297,0.0079383,0.003119004,-0.83391204,0.197245261,-0.06488383,-0.057579634,-0.11127163,-0.000793787,-0.040510806,0.021834764,-0.005958165,0.03090135,-0.024663343,-0.433195632,-1.234628448,0.786157369,1.498157368,-5.262163591,-4.658764473,-6.789347,-4.713685371,-5.934115723,-4.214905388,-3.950054783,-3.086343411 -4561,S264E,0.009047231,-0.006651471,-0.055327866,-0.974531957,-1.884315762,0.052465719,0.015055822,0.003038639,-0.058479227,-0.014600829,0.001297887,-0.078377858,-0.032277874,-0.511470599,-1.437593314,-1.515706286,-2.252925238,2.082525151,1.706585842,-6.417645518,-8.415867989,-7.417650856,-6.117900536,-5.406112679,-4.730695534,-4.148774767,-2.088664527 -4562,S264D,0.018067423,-0.026824038,-0.043720325,-1.065546375,-1.703690832,-0.01962617,-0.010836018,0.046970863,-0.052916713,-0.005694905,-0.047953171,-0.072899236,-0.014541413,-0.791693411,-1.339399339,-1.759576637,-1.647805026,2.284575869,1.699066663,-5.497707143,-7.437304512,-5.83582177,-4.96013649,-5.48496936,-3.770303581,-3.58429166,-0.861598106 -4563,S264G,0.007237908,0.011051019,0.000577772,0.008649558,-0.061236874,0.041796952,-0.029260193,0.043736008,-0.025330894,0.010216558,0.011885479,0.009074208,-0.007918665,0.041385054,-0.024085938,-0.048978782,-0.073494965,1.263727527,2.475357208,-5.452456358,-7.732986282,-6.3772957,-3.003225578,-6.449733459,-3.699040771,-2.929052827,-0.97637439 -4564,S264F,-0.047248112,0.006769254,-0.051402389,-1.000720125,-2.164877315,0.055535946,-0.016649745,-0.077846479,0.013667106,0.037400125,-0.023861618,-0.073724446,-0.029080332,-0.398822742,-1.602617508,-1.732769559,-2.596985071,1.268566926,1.353155061,-7.722145206,-8.456375229,-8.103623024,-7.760581276,-7.169959312,-7.120187187,-4.707118941,-1.939321599 -4565,S264I,-0.033589587,-0.012891226,-0.02702467,-0.722277784,-2.164144857,0.075654895,-0.030953253,-0.03622592,0.030057522,-0.043866128,0.018083676,-0.105514847,0.051465507,-0.235609313,-1.208946254,-1.72422794,-2.604061774,1.362867423,1.374491368,-7.109113107,-8.258719879,-7.161000496,-6.706025742,-8.298201195,-5.121618225,-5.128976596,-1.541540724 -4566,S264H,-0.008587872,-0.006339224,-0.046946083,-0.214581068,-1.974231479,0.040956653,-0.025746983,0.00857124,0.030057522,0.00697195,-0.019650398,-0.093980566,0.0000884,-0.006011116,-0.423151019,-1.779610079,-2.168852879,0.714015707,1.307921458,-5.922316867,-8.265671783,-7.062484726,-5.902382957,-5.209924622,-3.171120247,-4.930202457,-2.178370395 -4567,S264K,-0.039657526,-0.034307361,-0.073494226,-0.168587018,-1.853998581,0.155476683,-0.037307169,-0.042007883,0.04908076,-0.001001534,-0.067613187,-0.067089024,-0.079899428,0.043843447,-0.381017482,-1.468955435,-2.239041726,0.597885699,1.316738267,-5.056724313,-6.968138382,-5.191095184,-4.399631905,-5.127989655,-3.596766441,-4.021337011,-2.464426465 -4568,S264M,0.023053183,-0.045848403,-0.069584432,-0.007477978,-1.52296629,0.061818996,0.029275281,0.016831085,-0.073075855,-0.080248279,-0.011448526,-0.13363458,-0.005534283,0.031797778,-0.046753733,-1.443318378,-1.602614202,0.572263649,1.316109343,-7.922894038,-9.076979454,-7.029837952,-8.045745644,-8.39584037,-7.066066772,-5.492778447,-2.925700202 -4569,S264L,-0.041432687,-0.030345465,-0.020574312,-1.047610989,-2.185465744,0.037060113,-0.031695747,-0.051169627,0.018358647,-0.005608401,-0.055082528,-0.023675761,-0.017472863,-0.463251302,-1.631970675,-1.981119438,-2.38981205,1.595624795,1.372003958,-7.826166499,-9.651219727,-7.781398727,-8.754852638,-7.990710289,-4.952651115,-4.331150296,-0.954466482 -4570,S264N,-0.046606409,-0.010337215,-0.055456806,0.023379266,-1.146017061,0.088777492,-0.068721582,-0.024491236,-0.114434751,0.00534499,-0.026019419,-0.059124486,-0.051789125,0.079454035,-0.032695503,-0.715073467,-1.576960654,0.541930145,1.365331674,-0.322673293,-1.278372269,-0.534669998,0.054650536,0.062300659,0.082724609,-1.831595779,-1.157730756 -4571,S264Q,-0.017732409,0.006009731,-0.030076212,-0.032417856,-1.79312276,0.124951235,-0.020531708,-0.014933109,-0.040032546,0.023418415,-0.011398953,-0.038867097,-0.021285327,0.046852972,-0.111688684,-1.890589522,-1.695655998,0.586879577,1.299008959,-6.608459448,-9.616764198,-6.672174316,-6.946134224,-5.603032211,-4.204192291,-4.46778332,-1.679429613 -4572,S264P,-0.034996624,-0.040449641,-0.110291679,-1.516976807,-2.326807229,0.123103992,-0.021715626,-0.048277621,0.057076365,-0.042554357,-0.038344924,-0.08117772,-0.139405637,-1.155309702,-1.878643912,-2.021352885,-2.632261573,2.542090258,1.726625805,-6.001946898,-6.542418121,-5.977127998,-4.797720665,-7.061855209,-5.630612495,-3.124230551,-0.40762467 -4573,S264R,-0.033303892,-0.002158925,-0.01905306,-0.372489586,-1.654599757,0.244961174,-0.032306874,-0.03430091,-0.011666812,0.009141283,-0.013459132,-0.01837351,-0.01973261,-0.038957163,-0.706022009,-1.482227449,-1.826972064,0.669185008,1.319673223,-7.542838615,-10.02817562,-10.15477362,-6.442379288,-7.071416367,-4.017448181,-4.117887259,-1.50347734 -4574,S264T,-0.00930879,-0.025102462,-0.029694653,0.005860733,-0.031791011,0.00356107,-0.025066334,0.006448755,0.072809503,-0.04432208,-0.005882844,-0.061890586,0.002501281,0.023128661,-0.011407195,-0.037601047,-0.025980974,1.346499602,2.330677863,0.683239117,0.771968521,0.782404266,0.713986382,0.236060638,0.91177578,-0.800783747,-0.333621792 -4575,S264W,-0.03701137,-0.036335358,-0.040632846,-1.247204822,-2.23411749,0.048382807,-0.020247012,-0.053775727,-0.010028431,-0.044897094,-0.027773622,-0.052056143,-0.029209548,-0.787583277,-1.706826367,-1.953526177,-2.514708802,2.034163654,1.49591539,-9.473682346,-10.28819713,-10.10367625,-8.30988456,-9.432535858,-9.234117928,-5.572706863,-3.226737777 -4576,S264V,-0.050420781,-0.020685394,-0.017367231,-0.299916642,-1.869554148,0.064164998,-0.046807214,-0.054034348,-0.052773279,0.001802319,-0.043173106,-0.021708753,-0.013025709,-0.019476246,-0.580357038,-1.624429617,-2.114678679,0.78747563,1.319902724,-5.563815404,-6.643668869,-6.443362473,-4.921221222,-6.090290092,-3.720534363,-4.004210165,-1.308830387 -4577,S264Y,-0.060755017,-0.050137142,-0.023876904,-1.060690171,-2.358967997,0.06166054,-0.050158299,-0.071351735,0.061946667,-0.005199179,-0.095075104,-0.003293701,-0.044460106,-0.398842578,-1.722537764,-1.696105628,-3.021830366,1.634918919,1.443603763,-7.871698178,-9.174095192,-8.485197533,-7.22027623,-7.01420842,-7.464713516,-4.738063775,-2.986202946 -4578,Q265A,0.042492765,0.016703217,-0.002868155,-0.019031266,0.007296149,-0.014248719,0.024572262,0.060413268,0.012031506,-0.010741734,0.044148168,-0.002731134,-0.003005175,-0.026598755,-0.011463777,-0.003314102,0.0179064,1.342829858,2.71359507,-1.129456656,-1.251494225,-0.422832542,-0.183424431,-2.214410004,-1.575122078,-2.311807489,0.593920614 -4579,Q265C,0.015635141,0.012609201,-0.020334917,-0.038009941,-0.045596657,0.052913892,0.014886569,0.016383712,-0.027470312,0.00121696,0.024001441,-0.001143472,-0.039526361,-0.031116185,-0.044903697,-0.0236488,-0.067544513,1.307121673,2.563505598,-6.134131061,-6.774226074,-6.044303597,-5.361483208,-7.08680056,-5.403841866,-6.773408159,-4.767136179 -4580,Q265E,0.081935629,-0.002519987,-0.02770598,-0.018491827,0.02715064,-0.036268159,0.06425998,0.099611277,0.004952186,-0.026515013,0.02147504,-0.037661528,-0.017750431,-0.053911819,0.016928165,0.004552804,0.049748475,1.226168769,2.582372792,0.437351463,0.344221741,0.348820671,1.244198463,0.158474792,0.091041649,-2.053026874,0.706959306 -4581,Q265D,0.020641448,0.063860532,0.018170384,-0.028453658,0.018464877,-0.011419164,0.010613512,0.030669384,-0.058423798,0.072015577,0.055705487,0.059575121,-0.023234354,0.039229638,-0.096136953,0.074702899,-0.037773146,0.850566594,2.748503969,0.229366786,-0.115947937,0.315224503,1.4300998,0.097339432,-0.579881866,-1.116198971,0.647873967 -4582,Q265G,0.040053063,0.01710046,-0.006608361,-0.031994064,0.021784773,-0.025236466,0.019856672,0.060249453,0.007423393,-0.010085965,0.044286884,-0.009594656,-0.003622066,-0.031167682,-0.032820446,0.019872636,0.02369691,1.204277377,2.578432526,-1.86489353,-2.130836327,-1.156066597,-0.55668821,-1.970527275,-3.510349243,-2.937771102,0.04205366 -4583,Q265F,-0.022871247,-0.03495527,-0.029046293,-0.090125515,-0.072124116,0.051579801,0.013891222,-0.059633716,0.075610763,-0.055334234,-0.014576306,-0.052014193,-0.006078393,-0.08617291,-0.09407812,-0.055704778,-0.088543454,1.279019596,2.339457639,-6.134996568,-7.879184013,-5.207175606,-4.509172096,-6.066465126,-7.012986,-5.200715709,-1.584151303 -4584,Q265I,0.080185498,0.035607078,-0.000988701,0.005143107,0.013407068,-0.085509895,0.100398609,0.059972386,0.026559745,0.023815904,0.047398251,0.004361564,-0.006338966,-0.024131439,0.034417653,0.022708427,0.004105708,1.136173339,2.567076549,-5.068337535,-5.870093987,-4.451726433,-3.931287582,-4.430952339,-6.657627335,-4.471046367,-2.183539496 -4585,Q265H,0.045765925,-0.017652906,-0.001297824,-0.025484391,-0.011547412,-0.017816485,0.033014042,0.058517808,0.010030312,-0.035788245,0.000482434,-0.004678449,0.002082802,-0.044078275,-0.006890507,-0.002884024,-0.0202108,1.229680966,2.557797511,-1.845404556,-2.508680115,-1.968893433,-1.445414963,-1.920941002,-1.383093269,-2.180157505,-0.690860385 -4586,Q265K,0.010971079,-0.031122139,-0.01571936,-0.024909355,0.031578232,-0.014083993,0.022342211,-0.000400053,-0.022185543,-0.028182328,-0.034061949,-0.036885,0.00544628,-0.037527111,-0.012291599,0.034160832,0.028995632,1.151166808,2.571170035,0.080061525,0.480068321,-0.002937141,0.744700615,-0.270477417,-0.551046753,-1.629402059,0.806842299 -4587,Q265M,0.02582843,-0.020914929,-0.029816699,-0.02550843,0.012483782,-0.017426229,0.020487003,0.031169857,-0.022616796,-0.015085551,-0.026744306,-0.013464323,-0.046169075,-0.004050728,-0.046966131,0.00538879,0.019578774,1.177100104,2.659550514,-4.756326613,-5.212896141,-5.035090607,-3.986065788,-4.619007965,-4.928572563,-4.499075856,-1.692107595 -4588,Q265L,0.035553355,0.020213109,0.0090118,-0.007238047,0.009050001,-0.006434513,0.05102574,0.020080969,0.029917935,0.000399528,0.04002669,0.002464594,0.015559006,-0.013051078,-0.001425015,0.014565121,0.00353488,1.165991797,2.640183532,-4.552272302,-5.704207878,-5.106309517,-3.350710464,-3.331065086,-5.269068565,-4.201444347,-1.014486933 -4589,Q265N,0.035372497,0.009299083,-0.035646392,0.002078983,0.057900198,-0.03121396,-0.014231925,0.084976918,0.070297618,-0.025783485,0.044381651,-0.019869039,-0.051423744,-0.009376849,0.013534814,0.021476562,0.094323834,1.441815907,2.783022726,-1.079458675,-1.496175758,-0.698349777,-0.71786219,-0.881524574,-1.603381073,-2.922086161,-0.412021855 -4590,Q265P,0.033479285,0.014454858,0.000129577,-0.020894173,-0.002765732,-0.029154499,0.016946423,0.050012147,0.008520324,-0.004877412,0.033787127,0.002397539,-0.002138386,-0.026811322,-0.014977024,0.002547557,-0.008079021,1.26423606,2.658294344,-0.999888963,-0.130305054,-0.652441811,-0.057754715,-2.016401833,-2.142541405,-1.342867274,0.267389005 -4591,Q265S,0.032842689,-0.003225752,-0.020299962,-0.035852091,0.025386272,-0.025072192,0.011754074,0.053931304,0.003176281,-0.024987371,0.018535867,-0.018954552,-0.021645372,-0.028632496,-0.043071686,0.011617872,0.039154671,1.20546845,2.53240831,-0.855798248,-0.997512947,-0.419145889,-0.436036942,-1.684705551,-0.741589912,-1.650033429,0.424407591 -4592,Q265R,0.025854331,0.015738455,-0.01280294,-0.0308612,0.011668405,-0.00463903,0.04020749,0.011501171,0.003813734,-0.03355897,0.065035879,-0.019924399,-0.00568148,-0.045407093,-0.016315307,-0.008409514,0.031746323,1.279762208,2.593553737,-1.053425443,-1.591141479,-1.532817093,-0.444491821,-1.576588264,-0.122088554,-2.505593958,0.508513684 -4593,Q265T,0.038330228,0.01880192,-0.001908246,-0.04940008,0.016477116,0.000456617,0.023889612,0.052770844,0.025697313,-0.021200449,0.058804289,0.006705299,-0.01052179,-0.045376997,-0.053423162,0.013202536,0.019751695,1.308775547,2.591379482,-0.172983107,-0.046226387,0.533442772,0.508756027,-1.696491501,-0.164396446,-1.944324161,0.92285851 -4594,Q265W,0.048525862,0.028786002,-0.013611859,-0.0000459,-0.033193385,-0.027001742,0.034624267,0.062427456,0.050752981,-0.002604965,0.060176969,0.006136295,-0.033360013,0.001138241,-0.001230003,-0.0401415,-0.02624527,1.34675048,2.55281712,-5.824503432,-6.590552513,-5.337723747,-4.26220787,-5.549509895,-7.382523132,-5.481224246,-2.605343291 -4595,Q265V,0.004879323,-0.014099698,-0.048829454,-0.012788864,-0.015321832,-0.045433936,-0.008662755,0.018421401,0.012494984,-0.011635092,-0.016564304,-0.043106267,-0.054552641,0.005887527,-0.031465255,0.007340592,-0.037984255,1.222735381,2.665880571,-3.29796792,-3.975531593,-2.518202522,-1.868158638,-3.163455917,-4.964490929,-3.772100333,-0.428144896 -4596,Q265Y,0.119990645,0.071117446,0.006734652,0.02416805,0.036114718,-0.006760913,0.111442961,0.128538328,-0.004378883,0.003970088,0.138264804,-0.019849308,0.033318611,-0.004820483,0.053156583,-0.004563354,0.076792789,1.180671504,2.553011113,-4.794675983,-6.086442947,-4.037893433,-3.526507057,-4.862276871,-5.460259605,-4.971919866,-1.209698856 -4597,A266C,0.518992387,-0.016049777,0.031559423,0.043112156,0.001832707,,0.518992387,,0.028396724,-0.016049777,,0.031559423,,0.043112156,,0.001832707,,1.203283939,2.544351378,-9.611312599,-10.46384925,-9.678318954,-10.77058944,-8.699876961,-8.443928391,-7.485041592,-5.672047208 -4598,A266E,-0.048413773,-0.019240548,-0.015483557,0.030011612,0.035025403,,-0.048413773,,0.026226023,-0.019240548,,-0.015483557,,0.030011612,,0.035025403,,1.107517451,2.634571048,-7.519382849,-9.149027359,-6.131167389,-8.497146118,-6.732920784,-7.086652596,-5.072615722,-0.538610415 -4599,A266D,0.198842351,-0.012641397,-0.032308955,0.0000407,-0.064810058,,0.198842351,,0.029611426,-0.012641397,,-0.032308955,,0.0000407,,-0.064810058,,1.475864682,2.544887823,-9.38283797,-11.84464311,-8.755695053,-10.53382947,-7.918657578,-7.861364639,-4.86006911,-0.816376268 -4600,A266G,0.061345422,-0.024056809,-0.039491087,-0.000816358,-0.009499068,,0.061345422,,-0.009162203,-0.024056809,,-0.039491087,,-0.000816358,,-0.009499068,,1.671448915,3.643209181,-7.140749799,-8.363322487,-6.848897003,-7.263406754,-5.382646675,-7.845476074,-5.035819876,-1.682659433 -4601,A266F,0.29728185,-0.003769874,-0.136154465,0.007059595,-0.0305753,,0.29728185,,0.076606455,-0.003769874,,-0.136154465,,0.007059595,,-0.0305753,,1.323380862,2.587888183,-11.68021708,-12.26620926,-11.31065618,-14.78654055,-11.69767136,-8.340008034,-6.17774331,-4.104502726 -4602,A266I,0.162639222,-0.128283154,-0.17685156,-0.066386457,-0.246317916,,0.162639222,,-0.059967169,-0.128283154,,-0.17685156,,-0.066386457,,-0.246317916,,1.577214132,2.155083963,-7.742071185,-7.810437935,-7.847771866,-8.836214111,-6.9441707,-7.271761314,-4.735737828,-3.056502222 -4603,A266H,0.395601821,-0.004856734,-0.065801242,-0.011242262,-0.00282678,,0.395601821,,-0.041560178,-0.004856734,,-0.065801242,,-0.011242262,,-0.00282678,,1.340953251,2.612234521,-9.998361209,-12.16593826,-9.594224266,-11.02974333,-9.094475098,-8.107425095,-5.498129451,-3.344430205 -4604,A266K,-0.351159866,-0.056209012,-0.172911542,-0.069206022,-0.193697368,,-0.351159866,,-0.112633107,-0.056209012,,-0.172911542,,-0.069206022,,-0.193697368,,1.440037801,2.125370507,-7.974927737,-10.09508927,-6.280436195,-9.576574768,-6.556133965,-7.366404488,-3.996761111,-0.973117993 -4605,A266M,0.346037907,-0.019240548,0.04152471,0.03608576,0.062910106,,0.346037907,,0.119531911,-0.019240548,,0.04152471,,0.03608576,,0.062910106,,1.20498797,2.904508155,-10.01064075,-10.97800371,-8.981156006,-11.61887756,-10.30487699,-8.170289505,-6.891870127,-3.844259075 -4606,A266L,0.375059887,-0.081977752,-0.056799224,-0.009644789,-0.008888088,,0.375059887,,0.017646772,-0.081977752,,-0.056799224,,-0.009644789,,-0.008888088,,1.287897993,2.596848787,-7.803187184,-8.377955833,-6.980594543,-9.789633011,-8.096917603,-5.77083493,-3.451767255,-1.271377619 -4607,A266N,0.377743742,-0.102577754,-0.073634209,-0.002439102,0.08711741,,0.377743742,,0.068568172,-0.102577754,,-0.073634209,,-0.002439102,,0.08711741,,1.215730156,2.850969187,-10.28339501,-13.39398823,-10.64214191,-12.18014978,-9.699234589,-5.501460564,-5.700605346,-1.420583421 -4608,A266Q,0.228487823,0.014199504,-0.100464967,-0.023102158,-0.066046697,,0.228487823,,-0.012653862,0.014199504,,-0.100464967,,-0.023102158,,-0.066046697,,1.323575639,2.34226023,-7.997626971,-9.324178291,-7.001599434,-8.656268448,-7.305933113,-7.700155571,-3.8692734,-1.482195156 -4609,A266P,0.270350037,-0.057978523,-0.041024541,-0.174650781,-1.653566087,,0.270350037,,-0.011037471,-0.057978523,,-0.041024541,,-0.174650781,,-1.653566087,,1.210007353,1.35822011,-6.962914458,-9.598865906,-6.466596924,-7.479864662,-7.487980438,-3.781264359,-4.093011225,-0.846180737 -4610,A266S,0.342687258,-0.031926298,-0.024562632,0.013874632,-0.018780831,,0.342687258,,-0.029094094,-0.031926298,,-0.024562632,,0.013874632,,-0.018780831,,1.084257502,2.531067067,-4.845742529,-6.183047615,-4.620822983,-5.760386131,-4.541211754,-3.123244164,-4.170367827,-1.842786845 -4611,A266R,0.318462859,-0.053024392,-0.058928724,-0.003529293,-0.003314313,,0.318462859,,-0.006296708,-0.053024392,,-0.058928724,,-0.003529293,,-0.003314313,,1.187372712,2.582314897,-7.651654289,-9.359199837,-5.270740295,-8.895946068,-5.848240723,-8.884144524,-4.005418543,-1.389980308 -4612,A266T,0.140331348,-0.067703932,-0.031762258,-0.008374882,0.018746703,,0.140331348,,-0.039526008,-0.067703932,,-0.031762258,,-0.008374882,,0.018746703,,1.32210033,2.819818423,-4.942971735,-4.974907532,-5.545647827,-5.968902817,-4.467953407,-3.75744709,-3.900351198,-1.995959189 -4613,A266W,0.377702152,-0.084947144,-0.081613236,-0.001309972,-0.663916399,,0.377702152,,-0.019545738,-0.084947144,,-0.081613236,,-0.001309972,,-0.663916399,,0.94292984,1.468911328,-13.73109786,-14.65528414,-13.19512041,-16.38514017,-12.8600268,-11.55991778,-8.295016865,-5.767743586 -4614,A266V,0.254376094,-0.019583128,-0.062954898,-0.029222623,-0.017698685,,0.254376094,,-0.019365261,-0.019583128,,-0.062954898,,-0.029222623,,-0.017698685,,1.543610422,3.106887046,-5.093455186,-5.759747803,-5.173669151,-6.429858025,-4.742464447,-3.361536507,-3.987818968,-1.764718428 -4615,A266Y,0.400417842,0.005914131,-0.14388835,-0.037100529,-0.055057834,,0.400417842,,0.099842444,0.005914131,,-0.14388835,,-0.037100529,,-0.055057834,,1.456235439,2.55298152,-12.25742843,-12.64483664,-12.3985679,-15.19356399,-11.50240115,-9.547772491,-5.817980467,-2.904006218 -4616,T267A,0.03211872,-0.006044195,-0.01483234,-0.009837333,-0.036951636,-0.018845395,0.030240737,0.033996702,0.033248937,-0.049205145,0.037116756,-0.021773687,-0.007890993,-0.027901755,0.008227089,-0.055808522,-0.018094749,1.387397881,2.505001121,-3.255449571,-2.357781769,-3.271479462,-4.325927628,-2.823833847,-3.498225151,-3.500930263,-0.312082038 -4617,T267C,0.052386228,-0.007988031,-0.017080153,0.016619859,-0.121788154,-0.001304381,0.048250601,0.056521854,0.012554947,-0.070516827,0.054540765,-0.016327905,-0.0178324,0.00561382,0.027625897,-0.107718844,-0.135857463,1.176450469,2.129149516,-8.903374516,-7.485360588,-9.472220299,-9.863099419,-8.662179108,-9.034013168,-9.301718035,-7.784834906 -4618,T267E,0.018413899,0.014205472,-0.012188842,-0.033622154,-0.065889989,-0.015705672,0.01059256,0.026235238,0.036998691,-0.001549959,0.029960903,-0.024390584,0.0000129,-0.051035639,-0.016208669,-0.087593311,-0.044186666,1.400858968,2.371861213,-4.128007426,-3.669506615,-4.261348152,-6.183581947,-2.679595703,-3.846004715,-4.299408328,-0.308536818 -4619,T267D,0.061858767,-0.027677448,0.009052366,-0.010730389,-0.036252419,0.029058135,0.05749765,0.066219884,0.048856577,-0.06579162,0.010436724,-0.007860926,0.025965658,0.00976978,-0.031230557,-0.043956457,-0.02854838,1.30825329,2.462643277,-3.406375346,-3.018718948,-5.195660995,-4.065742531,-2.483276581,-2.268477676,-2.79502083,1.541141925 -4620,T267G,0.010315961,-0.017527341,-0.035547423,-0.007020734,-0.024747957,-0.022717051,0.006224506,0.014407415,0.040941757,-0.03663045,0.001575768,-0.018681014,-0.052413832,0.00040683,-0.014448298,-0.014541433,-0.03495448,1.210797152,2.526777108,-4.98173965,-4.02829277,-4.501563789,-5.9452575,-5.067787972,-5.365796219,-4.370599726,-0.786540949 -4621,T267F,0.000910825,0.005383098,-0.00542894,-0.004803304,-0.90864056,0.024608989,0.004806471,-0.002984821,0.046489371,-0.003090474,0.013856669,0.013920623,-0.024778502,-0.011535136,0.001928528,-0.627623814,-1.189657305,0.593006041,1.385254969,-8.949584862,-7.236138779,-10.97009499,-10.07858456,-7.793717125,-8.669388855,-7.209412452,-3.768400077 -4622,T267I,0.045688049,-0.026957819,0.005237958,0.000362835,-0.288237618,-0.054456405,0.064213678,0.02716242,0.002349416,-0.076006548,0.022090911,-0.016885516,0.027361431,-0.038437775,0.039163445,-0.249389463,-0.327085773,1.254612817,1.924629416,-7.990148303,-6.899457901,-8.301415733,-9.220891014,-7.895884682,-7.633092186,-6.809061037,-3.355514165 -4623,T267H,0.037923684,0.012100927,0.009698776,-0.027518158,-0.034456458,-0.028717992,0.02055315,0.055294217,0.057467101,-0.02328553,0.047487384,-0.000500253,0.019897805,-0.022008049,-0.033028267,-0.049272559,-0.019640357,1.321427578,2.414619047,-6.873257555,-5.648542435,-8.540943253,-7.926379997,-4.910652985,-7.339769104,-5.275638569,-1.616400498 -4624,T267K,-0.03611238,-0.014509779,-0.018261062,-0.063844271,-0.121983019,-0.042151835,-0.036885712,-0.035339047,0.088986119,-0.055874952,0.026855395,0.001669692,-0.038191816,-0.087109999,-0.040578542,-0.04647047,-0.197495568,1.221921648,2.345100803,-4.603173033,-4.25847625,-5.786440056,-5.705941887,-2.955097977,-4.309908997,-4.649029807,-1.30458173 -4625,T267M,-0.008897263,0.008307999,-0.009642578,-0.015124475,-0.172746861,-0.029690465,-0.061562867,0.043768341,-0.025272205,-0.025207733,0.041823731,0.01200675,-0.031291905,0.024637057,-0.054886007,-0.141976282,-0.203517439,1.352136281,2.22547064,-8.39117921,-7.023262253,-9.524322037,-9.651534805,-8.062188965,-7.69458799,-6.963229811,-3.98240907 -4626,T267L,0.002720721,-0.009713904,-0.028805222,-0.0000667,-0.154958829,-0.000711953,-0.007764748,0.013206189,0.037062531,-0.04505272,0.025624912,-0.016498233,-0.041112211,-0.019024258,0.018890904,-0.148005568,-0.16191209,1.419723899,2.237395253,-7.817072113,-6.007908676,-8.935391541,-9.564654678,-7.686483978,-6.890921692,-5.750315952,-2.872017227 -4627,T267N,0.019529344,0.037702328,-0.018547291,-0.008369744,0.071822402,-0.043361142,-0.033438609,0.072497296,0.00852039,-0.000650399,0.076055054,-0.012979435,-0.024115147,0.047568923,-0.064308411,0.017068227,0.126576576,1.106124803,2.581262974,-3.955632893,-3.500690857,-5.487015953,-3.554760078,-3.170759445,-4.064938133,-4.17054663,-0.055879196 -4628,T267Q,0.008167373,-0.02651603,-0.007097838,-0.024037403,-0.078434605,-0.015682951,0.031362216,-0.01502747,-0.007958884,0.011592419,-0.064624479,0.02033099,-0.034526666,0.017150749,-0.065225554,-0.040019739,-0.11684947,1.263908535,2.456590378,-5.793194141,-4.276433571,-6.845551781,-7.625619507,-4.064447113,-6.153918732,-4.940045997,-0.973008594 -4629,T267P,0.02059026,-0.002914247,-0.016694784,-0.00839914,-0.002425347,-0.009897896,0.015271322,0.025909198,0.018311978,-0.035202189,0.029373696,-0.021112694,-0.012276873,-0.031162145,0.014363865,-0.030052358,0.025201665,1.039176675,2.29824289,-2.859259259,-2.109662727,-1.821796974,-4.480303108,-3.051701172,-2.832832314,-3.000199534,-0.082581052 -4630,T267S,0.025183801,0.011991652,-0.013140152,-0.003108123,0.006278958,0.003569424,0.015119255,0.035248347,0.026973968,-0.004064626,0.02804793,-0.014941042,-0.011339261,-0.007085261,0.000869015,0.001946152,0.010611764,1.269608364,2.781116593,-0.450986351,0.292122444,-0.368622528,-0.562178108,-0.525494385,-1.090759178,-2.407859556,0.795068914 -4631,T267R,0.02113183,-0.012404533,-0.046325991,-0.005726378,-0.101628915,-0.012564825,0.017752559,0.0245111,0.047787156,-0.056531787,0.031722722,-0.038460142,-0.054191839,-0.028401947,0.016949191,-0.092651755,-0.110606074,1.38287457,2.312930052,-6.026580502,-4.945185204,-6.508542847,-7.726665703,-4.983372787,-5.969135971,-5.377578659,-1.235775358 -4632,T267W,-0.016843853,-0.008948143,-0.025229775,-0.028948133,-1.686777913,-0.041581739,-0.025017234,-0.008670471,0.006202142,-0.033081608,0.015185323,-0.031691856,-0.018767694,0.012874781,-0.070771046,-1.562030605,-1.811525221,0.721142841,1.318600446,-10.08778003,-8.461348816,-11.17075563,-11.49661557,-9.372375832,-9.937804306,-8.526535907,-5.501191559 -4633,T267V,0.012456952,-0.026528242,-0.024470424,-0.01012388,-0.110030804,-0.00334005,0.00293946,0.021974444,0.061917409,-0.061753757,0.008697274,-0.018002919,-0.030937928,-0.012071091,-0.008176668,-0.111509717,-0.10855189,1.463126322,2.369827496,-5.876105426,-5.100013054,-5.732343796,-6.966497261,-5.742238388,-5.839434631,-5.723408009,-1.898301145 -4634,T267Y,0.012717865,-0.021391266,-0.054047465,-0.025338293,-1.040756044,0.031263901,0.032958646,-0.007522916,-0.010151669,-0.082301345,0.039518813,-0.046377485,-0.061717445,-0.046798745,-0.003877841,-0.787811555,-1.293700532,1.070974179,1.474675182,-8.932333969,-7.231935089,-11.11934265,-9.673723946,-7.599572098,-9.037096062,-6.692925279,-3.260841987 -4635,M268A,0.028022634,0.00181098,0.044088028,-0.000479489,-0.68416902,-0.106105774,0.039725257,0.016320011,-0.093096223,0.008390383,-0.004768424,0.018469469,0.069706587,-0.017796991,0.016838014,-0.51010241,-0.85823563,0.713424196,1.438726862,-5.836268771,-4.934040726,-4.700607636,-6.773074318,-7.563693153,-5.209928024,-4.415452588,1.80880537 -4636,M268C,0.082805197,0.003224159,0.075770314,0.002473344,-1.6200068,-0.133695215,0.092384275,0.073226119,-0.021193027,-0.008631166,0.015079483,0.042704179,0.108836448,0.050167776,-0.045221088,-1.441721282,-1.798292318,0.709823912,1.325910141,-10.6506174,-10.08426623,-9.269208977,-11.41772983,-11.73278481,-10.74909715,-9.576490197,-7.088049726 -4637,M268E,-0.025403509,-0.01330414,0.018856714,-0.022577656,-1.721577351,-0.107603036,-0.030769456,-0.020037561,-0.033942224,0.040645153,-0.067253432,-0.001750609,0.039464036,-0.006397233,-0.038758078,-1.357126217,-2.086028484,0.74592107,1.333068599,-8.965994157,-8.873480026,-7.351934868,-9.794858421,-10.02484447,-8.784852997,-4.512979099,0.743119368 -4638,M268D,0.049559694,0.028195345,0.07424284,-0.004221616,-1.304387473,-0.136454111,0.032070072,0.067049315,-0.012517559,0.049534085,0.006856605,0.011596012,0.136889667,-0.003517083,-0.004926148,-1.31264356,-1.296131386,0.683122251,1.329731004,-8.655913069,-8.121978897,-8.318828987,-9.431975624,-9.434560875,-7.972220963,-3.985179467,0.916457321 -4639,M268G,0.02292139,0.0193231,0.068683225,0.010629656,-1.144386625,-0.102823661,0.029319029,0.016523751,-0.062661534,0.047815919,-0.00916972,0.047167943,0.090198506,0.005485635,0.015773676,-0.828937425,-1.459835824,0.69215041,1.372410614,-8.51344326,-8.118465034,-8.056979355,-8.565453255,-9.500549026,-8.32576963,-5.054692613,-0.283474921 -4640,M268F,0.033353528,-0.062578457,0.014290657,-0.04316767,-0.117011117,-0.026667793,0.063537845,0.00316921,-0.083314192,-0.064973928,-0.060182986,-0.032043969,0.060625282,-0.06586419,-0.020471149,-0.089679706,-0.144342528,1.498346185,2.484717432,-2.261966063,-2.458199707,-0.469075829,-2.795057747,-2.072433563,-3.515063469,-3.420991853,0.0177629 -4641,M268I,-0.001496065,0.057875014,0.090556975,0.056882353,-0.068482321,0.029583121,0.010712104,-0.013704233,-0.085637899,0.100551434,0.015198594,0.077835663,0.103278286,0.087481288,0.026283417,-0.047065109,-0.089899532,1.28675207,2.551786355,-2.401178044,-3.032053986,-1.933561119,-2.155156891,-2.583850685,-2.30126754,-3.51199769,-0.442611812 -4642,M268H,0.038575572,0.008781273,0.046621278,0.001992934,-0.644612417,-0.131856989,0.052765327,0.024385817,-0.063784701,0.00374099,0.013821555,0.001592182,0.091650374,0.003808396,0.000177472,-0.499021861,-0.790202973,1.395491554,1.773955546,-10.43987309,-11.12247461,-7.735003464,-11.63664337,-10.8105123,-10.8947317,-6.719768196,-1.190047857 -4643,M268K,0.006216201,0.031239483,0.05780349,0.013144583,-1.519471323,-0.109617614,0.010645461,0.00178694,-0.06570203,0.048069313,0.014409653,0.057849892,0.057757087,0.058045483,-0.031756318,-1.348765419,-1.690177227,0.574288409,1.32060653,-7.917690201,-6.747980278,-6.907358742,-8.826274437,-9.495972252,-7.610865295,-4.864241378,-0.889966133 -4644,M268L,0.014769506,0.016643451,0.053684337,-0.002688449,-0.078608888,-0.023333704,0.033846215,-0.004307203,-0.065944611,0.037797356,-0.004510455,0.01350615,0.093862524,0.009980349,-0.015357246,-0.058765038,-0.098452737,1.35503312,2.454176044,-1.722978513,-1.94728965,-1.16584848,-1.469435661,-2.635960495,-1.396358276,-2.335030607,0.480190097 -4645,M268N,0.015316806,0.008046075,0.03604879,-0.017395317,-0.97278755,-0.059982501,0.039555816,-0.008922204,-0.049154338,0.060901661,-0.044809511,0.05492667,0.017170909,0.043805416,-0.07859605,-0.686175663,-1.259399436,0.594349228,1.376528205,-9.497814194,-8.954752563,-8.446674973,-9.469679176,-11.07690672,-9.541057533,-5.688370574,0.191226639 -4646,M268Q,0.006675641,0.011014374,0.040575623,0.010439831,-0.588147508,-0.090680076,0.015438134,-0.002086852,-0.035106212,0.021182521,0.000846226,0.007162203,0.073989042,0.03027648,-0.009396818,-0.408099754,-0.768195262,0.944328774,1.56916387,-9.022070648,-8.198333984,-7.170684196,-10.14937446,-10.37732929,-9.21463131,-5.471202571,0.403547303 -4647,M268P,-0.025339066,0.012548151,0.053719085,-0.010209923,-0.665290805,-0.095248458,-0.021348835,-0.029329297,-0.073546543,0.031901041,-0.006804739,0.045670109,0.061768061,-0.005047329,-0.015372517,-0.474359695,-0.856221915,1.137036883,1.620821168,-5.893184334,-4.703662521,-5.119691834,-6.555620514,-6.951009552,-6.135937248,-4.647321825,-0.227785848 -4648,M268S,0.027183596,0.004268478,0.052981494,0.003781332,-0.823971461,-0.100674754,0.052093667,0.002273525,-0.055219746,0.012769488,-0.004232532,0.015448443,0.090514545,0.022158779,-0.014596116,-0.645963591,-1.00197933,0.657247371,1.39387013,-6.548250322,-5.051669838,-5.004062248,-7.253809814,-7.957999001,-7.473710709,-4.237564153,-0.130169311 -4649,M268R,0.017703935,0.000784066,0.041178194,-0.021773518,-1.426233086,-0.10689817,0.034836046,0.000571824,-0.063068852,0.012880243,-0.011312112,0.016945289,0.065411099,-0.026772577,-0.016774458,-1.244938619,-1.607527552,0.9268493,1.36305355,-8.132532494,-6.481900253,-6.266915627,-9.116715881,-9.923524857,-8.87360585,-4.412497207,0.024086307 -4650,M268T,0.007653911,0.012619863,0.049142689,-0.004214333,-0.601201794,-0.084826512,0.020362385,-0.005054564,-0.046460419,0.037361978,-0.012122253,0.032333621,0.065951757,-0.01256315,0.004134484,-0.421223316,-0.781180271,0.914113788,1.554296162,-6.178755037,-5.851721291,-4.862786659,-6.981656029,-7.348989243,-5.848621964,-5.096371896,0.040626767 -4651,M268W,-0.004153718,0.031237211,0.04557365,0.000706916,-0.249969002,-0.011602582,-0.032244917,0.023937481,-0.083850833,0.057575757,0.004898664,0.01452416,0.076623139,0.015729777,-0.014315946,-0.178129622,-0.321808382,1.524120394,2.287724827,-8.215593687,-8.339175888,-6.715449234,-8.196621864,-9.488346466,-8.338374985,-7.719934077,-4.209013455 -4652,M268V,0.042375064,-0.000120378,0.048121945,0.017640564,-0.21220918,-0.066274742,0.063631004,0.021119123,-0.034453794,0.01527118,-0.015511935,0.009329466,0.086914424,-0.002046541,0.037327668,-0.154989,-0.269429359,1.249041308,2.076863988,-3.574595856,-3.953622078,-2.307736961,-3.518914757,-3.984887398,-4.107818085,-4.599357159,-0.23475161 -4653,M268Y,-0.030099196,-0.002161302,0.00696042,-0.060742938,-0.670814771,-0.0533588,-0.029492392,-0.030705999,-0.037330952,0.028046725,-0.032369328,-0.01087392,0.024794759,-0.078375085,-0.04311079,-0.482572404,-0.859057138,1.502627466,1.849521703,-7.0260339,-7.653235947,-5.527852211,-6.993723747,-6.635228119,-8.320129478,-6.132814914,-1.142366709 -4654,D269A,0.051102666,-0.035273753,0.036073834,0.003493326,-0.017503169,-0.003989707,0.057147643,0.045057689,-0.052946949,-0.033426776,-0.03712073,0.019110876,0.053036791,0.026735019,-0.019748368,-0.027523005,-0.007483332,1.335942157,2.579761923,-0.674442964,-1.014336182,-0.404730972,-1.200135452,-0.493083298,-0.259928917,-2.964403311,0.657361391 -4655,D269C,-0.030770863,-0.047987552,0.035372828,0.012540753,-0.248746876,-0.044170713,-0.06494373,0.003402005,-0.023248827,-0.016819614,-0.07915549,0.032071743,0.038673912,0.053870393,-0.028788888,-0.219037772,-0.278455979,1.15441025,1.922109238,-8.174430284,-8.617481384,-8.296215332,-9.277652939,-7.714647438,-6.966154327,-8.739158639,-7.825748977 -4656,D269E,0.069690628,-0.022694297,0.063534603,0.010276244,-0.028764449,0.003450122,0.095048891,0.044332365,-0.005995537,-0.027233044,-0.01815555,0.019180088,0.107889118,0.005166512,0.015385975,-0.051776836,-0.005752062,1.246647087,2.42582167,-0.96290901,-1.518897026,-0.393354507,-1.40404631,-0.484152084,-1.014095123,-2.007282661,0.637694037 -4657,D269G,-0.014087449,-0.047609231,0.025288663,-0.01368996,-0.055161396,-0.036859391,-0.028955372,0.000780474,-0.017765658,-0.014858583,-0.080359879,0.05014948,0.000427846,0.050443311,-0.07782323,-0.039782219,-0.070540572,1.126542494,2.431668703,-3.863792229,-4.504075882,-2.902243027,-4.477942627,-3.418045425,-4.016654182,-3.712730827,-1.053526039 -4658,D269F,-0.009014459,-0.036679361,0.03621572,-0.026963981,-0.127854174,-0.056867936,-0.030690704,0.012661787,-0.007149042,-0.037827995,-0.035530727,0.072120209,0.000311231,0.008382588,-0.062310549,-0.073383082,-0.182325265,1.381488188,2.474124857,-7.864631914,-8.34650367,-8.374730827,-8.992585808,-7.73060006,-5.878739204,-6.210028953,-3.015647867 -4659,D269I,0.173859801,-0.014213369,0.018566311,0.016979829,-0.008056493,-0.054091047,0.161908955,0.185810646,0.045683539,-0.103519102,0.075092364,-0.064256383,0.101389005,-0.056088007,0.090047664,-0.103263162,0.087150176,1.490862979,2.350063778,-5.883578241,-6.244813026,-5.862176491,-6.855109688,-5.716116669,-4.739675331,-5.766905226,-2.271021291 -4660,D269H,-0.046883776,-0.066250988,0.068053543,-0.021062612,-0.07581602,-0.018070605,-0.081046964,-0.012720588,0.043668248,-0.028394626,-0.104107349,0.059739308,0.076367777,0.036635161,-0.078760384,-0.029540275,-0.122091764,1.22273188,2.520490165,-4.60961597,-4.090373688,-5.007695686,-5.853297386,-3.876361618,-4.220351471,-5.450312124,-2.08337262 -4661,D269K,-0.099158329,-0.110053949,-0.083752889,-0.122898966,-0.127878216,-0.111624224,-0.142661639,-0.055655019,0.012271235,-0.059174961,-0.160932936,-0.008045898,-0.159459879,-0.104640483,-0.141157448,-0.157230622,-0.098525809,1.456416069,2.23460833,-1.952627034,-2.313077362,-2.2424674,-3.344438171,-1.05825396,-0.804898277,-1.723270608,0.107547527 -4662,D269M,0.043389405,-0.071248708,0.002566298,-0.024322301,-0.063459543,-0.03200592,0.031549753,0.055229057,-0.035757211,-0.079669492,-0.062827923,-0.065230356,0.070362951,-0.06503091,0.016386308,-0.107984804,-0.018934281,1.414112611,2.387959858,-6.734389999,-7.187047043,-6.965687141,-7.433446068,-6.487710114,-5.598059631,-6.042017246,-3.416355767 -4663,D269L,0.047875269,-0.031406776,0.042570263,0.006769323,-0.07140762,-0.006988763,0.048120807,0.04762973,-0.031450713,-0.008431788,-0.054381764,0.036688985,0.048451541,0.030609887,-0.017071242,-0.089446235,-0.053369004,1.321713496,2.361110558,-5.789163791,-6.351070518,-6.112086037,-6.636318169,-5.439526604,-4.406817627,-5.030517319,-1.729795671 -4664,D269N,0.016199764,-0.005721142,0.08172407,-0.019859105,-0.039656706,-0.014000137,-0.004156434,0.036555961,-0.050249433,-0.008059304,-0.00338298,0.111476621,0.051971519,0.014113471,-0.053831681,-0.04857385,-0.030739562,1.372238555,2.532056121,-2.615338319,-2.514645042,-2.649364311,-3.373726952,-2.367295242,-2.171660049,-2.759974525,-0.54730329 -4665,D269Q,0.00181108,-0.040102944,0.024425894,-0.016140259,-0.07497792,-0.111944763,-0.031600861,0.035223021,0.057921743,-0.037712083,-0.042493805,0.003083177,0.04576861,0.05864754,-0.090928057,-0.069691642,-0.080264197,1.244562121,2.363300113,-2.825870198,-3.597037498,-2.875212326,-3.781540764,-2.413122101,-1.462438301,-3.820057997,-0.818943962 -4666,D269P,0.021723585,-0.038386716,0.006374778,-0.011030802,-0.097253951,-0.050581569,0.019002346,0.024444824,-0.042526189,-0.017607266,-0.059166165,0.002257383,0.010492173,0.039616616,-0.06167822,-0.092860079,-0.101647822,1.430450313,2.455656409,-2.660415147,-4.033313049,-2.895181587,-2.771419807,-2.210753395,-1.391407898,-2.893227374,0.77993807 -4667,D269S,-0.01871066,-0.049684078,0.0000121,0.010309779,-0.041011648,-0.035341633,-0.031269003,-0.006152316,-0.035036898,0.00403087,-0.103399025,0.066390582,-0.066366468,0.071654269,-0.051034711,-0.037176777,-0.044846518,1.372664007,2.687981633,-2.357086189,-3.076577683,-2.187303337,-3.080949554,-2.174569176,-1.266031197,-3.000346976,-0.791845686 -4668,D269R,-0.00517351,-0.056264374,0.009622668,-0.023041055,-0.115253874,-0.040144037,-0.020781741,0.010434721,-0.054668734,-0.034857697,-0.07767105,0.009543546,0.009701789,0.015566232,-0.061648341,-0.102670105,-0.127837643,1.410213838,2.421800229,-3.455981917,-3.685769569,-3.397672821,-4.634147186,-2.914312874,-2.648007133,-4.702547644,-0.971151257 -4669,D269T,0.031119606,-0.043040631,0.039245758,0.011763764,-0.040370777,-0.019499406,0.00569136,0.056547852,-0.047339543,-0.023459409,-0.062621852,0.032858419,0.045633097,0.064554285,-0.041026758,-0.027152246,-0.053589307,1.396418939,2.684515578,-2.429630251,-2.735876694,-2.547397865,-3.380374435,-1.579773285,-1.904728973,-2.812433779,-0.5746494 -4670,D269W,0.014771783,-0.098888497,0.045701301,-0.044088059,-0.17828193,-0.018523331,0.011422299,0.018121267,-0.01534352,-0.070227935,-0.127549059,0.084389903,0.007012698,-0.009831863,-0.078344254,-0.13791394,-0.21864992,1.361759848,2.235593191,-8.125564102,-8.473323181,-8.180314888,-9.229200714,-7.996783707,-6.748198021,-6.860639339,-4.429510195 -4671,D269V,0.003310634,-0.084350413,0.012678241,-0.046586452,-0.059219047,-0.016439551,0.004220794,0.002400473,-0.005018627,-0.082364699,-0.086336127,0.00379689,0.021559592,-0.025878517,-0.067294387,-0.076527508,-0.041910586,1.282274329,2.283398773,-3.705761815,-3.718711266,-3.629392029,-4.516423828,-3.750159569,-2.914122383,-4.064445108,-1.005542191 -4672,D269Y,-0.010307908,-0.118091607,-0.052462603,-0.050583308,-0.124998827,0.020011073,-0.049679065,0.02906325,-0.087674286,-0.096041891,-0.140141322,-0.050340486,-0.05458472,0.037281336,-0.138447952,-0.082701389,-0.167296265,1.356455985,2.37120265,-6.630472472,-6.626988792,-8.1744925,-7.925972389,-5.716406578,-4.708502098,-5.608159554,-1.965443775 -4673,E270A,0.091651093,-0.023237382,0.037808646,0.197033925,0.078759389,-0.02456431,0.062776848,0.120525337,0.071866954,-0.019212703,-0.02726206,-0.088314115,0.163931407,0.123685134,0.270382716,0.039040369,0.118478408,1.027434188,2.893681162,-2.823240953,-2.524744736,-2.706115807,-3.258204369,-2.889568604,-2.737571251,-4.531912638,0.076322243 -4674,E270C,0.037849531,-0.056735985,-0.034056364,0.101675529,-0.244633761,-0.066169072,0.012326042,0.063373019,0.039927947,-0.055655177,-0.057816793,-0.188727007,0.12061428,-0.00085431,0.204205367,-0.206352104,-0.282915417,1.393059971,2.083729143,-9.484078505,-9.272044418,-9.688048126,-10.96170597,-8.699922859,-8.79867115,-8.105426653,-5.811157538 -4675,E270D,0.071480486,0.049407767,0.113168499,0.1973616,0.111175353,-0.067214884,0.082137801,0.06082317,0.070581074,-0.035874257,0.134689791,0.009029317,0.217307681,0.115000214,0.279722986,0.068048738,0.154301968,1.15557715,2.906122685,-2.866748286,-2.892088852,-2.18089743,-3.552958504,-2.840751556,-2.86704509,-3.390357855,-0.874838448 -4676,E270G,0.150667204,-0.00119775,-0.039345302,0.073918248,-0.592299057,-0.101817035,0.136451215,0.164883193,0.100038198,-0.023840909,0.02144541,-0.11965314,0.040962537,0.04441914,0.103417355,-0.386548025,-0.798050089,1.055090209,1.648664868,-6.127391969,-7.111399879,-5.269039658,-7.200362114,-4.834701126,-6.221457069,-4.662094777,-1.391147713 -4677,E270F,0.013703646,-0.049621599,-0.163358752,-0.05995315,-0.148212625,-0.178001288,0.022748066,0.004659225,-0.044582133,-0.025632138,-0.07361106,-0.388180171,0.061462668,-0.179904229,0.05999793,-0.222308078,-0.074117172,1.800293665,2.319079553,-8.87487885,-7.947089523,-8.940777435,-11.76601304,-8.654778038,-7.065736214,-5.558665513,-3.480137288 -4678,E270I,0.084472222,0.019155819,0.028798893,0.198463243,-0.067328252,-0.012445091,0.057431928,0.111512515,-0.027152246,-0.217605783,0.255917421,-0.206125965,0.26372375,-0.106994492,0.503920978,-0.056644288,-0.078012216,1.387026486,2.343490509,-4.981078366,-4.884583359,-5.49786544,-4.932682381,-4.579838165,-5.010422485,-4.686844549,-2.440363347 -4679,E270H,0.155921244,0.003732139,-0.038773427,0.086259193,-0.007309004,-0.102296379,0.154761347,0.157081141,0.098286542,-0.11270428,0.120168557,-0.185725218,0.108178365,-0.101708896,0.274227282,-0.08027919,0.065661182,1.356222896,2.244818374,-6.934721574,-6.795305717,-7.141623245,-8.805610512,-7.277054512,-4.654013886,-5.926598518,-2.242733038 -4680,E270K,0.080472677,-0.147520202,0.024444241,0.119127625,-0.081976048,-0.234088694,-0.018288786,0.179234139,-0.096910013,-0.261357291,-0.033683113,-0.077942174,0.126830656,-0.045757491,0.284012741,0.002015291,-0.165967386,1.312050494,2.647915167,-4.592292458,-5.255593567,-4.579212524,-5.390334213,-3.931627098,-3.804694885,-4.937800765,-1.52398333 -4681,E270M,0.117930537,-0.179357172,-0.079502447,-0.049851457,-0.310200101,0.007087503,0.053797644,0.182063429,0.164810249,-0.377522103,0.01880776,-0.383771052,0.224766159,-0.159700843,0.05999793,-0.257152258,-0.363247944,2.049690423,2.505608249,-5.316188264,-4.991301628,-6.156343216,-5.385351654,-5.576166893,-4.471777931,-4.894227677,-3.205877278 -4682,E270L,0.108808338,-0.033873145,0.006217116,0.107678468,-0.017462942,0.071375882,0.115369945,0.10224673,0.010995384,-0.084736081,0.016989791,-0.157637682,0.170071914,-0.038115748,0.253472684,-0.115562346,0.080636463,1.310213176,2.236142834,-4.230964418,-3.466830322,-5.858892876,-4.616414719,-3.979298302,-3.233385872,-4.340833464,-2.326500595 -4683,E270N,-0.021896967,-0.214591041,-0.061553189,-0.031661058,-0.065881175,-0.047692317,-0.009936711,-0.033857222,0.166331422,-0.081631747,-0.347550334,-0.167061943,0.043955565,0.057008267,-0.120330382,-0.090130932,-0.041631418,1.089609965,2.12619429,-5.678670201,-5.481844498,-6.118224297,-6.639164665,-4.613272736,-5.54084481,-4.832668534,-2.181981968 -4684,E270Q,0.32779339,-0.180419018,-0.014080337,0.030100793,0.067281052,-0.08403233,0.294221028,0.361365752,0.246672333,-0.605295835,0.244457799,-0.286155443,0.257994769,-0.149235409,0.209436994,-0.178066451,0.312628554,1.693481663,2.304284563,-1.761125568,-1.969540421,-2.758951294,-1.398242294,-1.996290474,-0.682603355,-2.239960196,-0.876759223 -4685,E270P,0.029197373,-0.023891091,-0.056959566,-1.340285675,-1.986815688,-0.106119093,0.001397468,0.056997277,0.00604596,-0.051357814,0.003575633,-0.141432914,0.027513783,-0.913378324,-1.767193025,-1.849068256,-2.12456312,2.471440835,1.77898438,-7.581453,-7.904668289,-7.333040169,-8.63092318,-7.216234177,-6.822399185,-4.904808081,-1.325246367 -4686,E270S,0.043260195,-0.017773047,0.004583866,0.101468164,-0.039686684,-0.035918412,0.041107391,0.045412999,0.06366908,-0.037167325,0.001621232,-0.089841397,0.099009129,0.063085908,0.139850419,-0.047672493,-0.031700874,1.285933114,2.532038708,-5.68598898,-5.799924248,-5.571584763,-6.862362778,-5.055758064,-5.140315048,-4.731199162,-1.415635969 -4687,E270R,0.049859271,-0.076785835,-0.096408568,0.05169493,-0.210595029,-0.041734467,0.011364338,0.088354204,0.021002947,-0.13743129,-0.016140379,-0.148494769,-0.044322367,-0.044307424,0.147697284,-0.301909135,-0.119280923,1.558660261,2.091780322,-4.994813402,-4.893377205,-5.176808868,-5.979057739,-5.441427979,-3.483395218,-4.115780973,-0.861815857 -4688,E270T,0.141304054,0.037794904,0.002968223,0.150036634,0.004322527,-0.046202888,0.120072924,0.162535184,-0.010219165,0.022211278,0.05337853,-0.113328715,0.11926516,0.072506358,0.22756691,-0.011290176,0.019935229,1.243936137,2.703743926,-2.810873518,-2.093369499,-3.894014534,-2.839039093,-2.733845497,-2.494098969,-3.495288191,-0.826149449 -4689,E270W,-0.040624409,0.042032106,-0.053543355,0.099084282,-0.625633446,0.110624469,-0.060145709,-0.021103108,0.100115153,0.100018557,-0.015954346,0.079855093,-0.186941802,0.194574665,0.003593898,-0.509474865,-0.741792027,0.410732081,1.373019198,-9.305013268,-9.699569504,-9.118012726,-11.14501562,-8.817969315,-7.744499176,-5.390238897,-3.167902641 -4690,E270V,0.055540807,-0.048362614,-0.038161704,0.115619836,-0.007478681,-0.03275788,0.001353778,0.109727835,0.009870754,-0.125760486,0.029035258,-0.134484055,0.058160648,-0.006217375,0.237457046,-0.116674496,0.101717134,1.417640351,2.286600498,-2.823124092,-2.185381927,-2.850980286,-2.480425499,-3.108802666,-3.490030083,-4.565133199,-1.344716189 -4691,E270Y,0.114330944,-0.128712801,0.012145378,0.064690812,-0.157183129,-0.127516339,0.087655911,0.141005977,-0.083546051,-0.031204378,-0.226221223,-0.169022643,0.193313399,0.050248683,0.07913294,-0.16106784,-0.153298418,1.250853078,2.066913331,-8.107741341,-8.404937721,-8.348278793,-11.12999238,-7.442288383,-5.213209427,-4.485849636,-1.06583056 -4692,R271A,-0.005525892,0.033199527,0.039465529,0.021896495,-0.226637311,-0.011157455,0.00059959,-0.011651373,-0.020114826,0.078244238,-0.011845185,0.041577429,0.037353628,0.029349573,0.014443416,-0.138509057,-0.314765564,1.338780602,2.222551131,-5.578510826,-4.195139191,-7.777621727,-5.702666344,-5.348579155,-4.868547714,-4.101888514,-0.000559988 -4693,R271C,-0.03578944,-0.010230463,0.012696216,-0.012113344,-0.162333769,0.004289188,-0.0711741,-0.000404779,0.016428191,0.014550425,-0.035011351,0.04657366,-0.021181228,0.02428035,-0.048507038,-0.088974462,-0.235693076,1.264454929,2.305016571,-7.358436671,-8.264018593,-7.716170105,-7.453663033,-8.07056739,-5.287764236,-5.315231642,-3.921526479 -4694,R271E,-0.053015369,0.027476642,0.031208071,-0.429989016,-2.389584217,-0.067555845,-0.058059261,-0.047971476,0.02274703,0.070172473,-0.01521919,0.061428715,0.000987427,-0.00868117,-0.851296862,-1.667864802,-3.111303631,0.698024895,1.313191549,-10.45165013,-11.05660411,-10.06568335,-11.00951213,-12.57478398,-7.551667084,-4.909823619,-3.039044066 -4695,R271D,0.065735182,0.082801283,0.068888275,0.085816287,-1.609124252,-0.091853302,0.066896171,0.064574193,-0.027707467,0.087219053,0.078383513,0.085752177,0.052024372,0.121159903,0.050472671,-1.341387684,-1.87686082,0.499341658,1.315851796,-11.19416054,-9.769874512,-11.71138618,-11.72797646,-12.31688966,-10.44467587,-3.782286027,-0.628842501 -4696,R271G,0.007470402,0.01804001,0.036807649,0.013305932,-0.999188349,-0.067928491,0.009629181,0.005311623,0.024342446,0.022514778,0.013565241,0.033601465,0.040013832,0.006623359,0.019988505,-0.782202894,-1.216173803,0.855816799,1.412696736,-9.358883806,-8.851324371,-13.61061343,-9.213291161,-8.610203346,-6.508986717,-4.607707355,-0.788220178 -4697,R271F,0.103431544,0.074901741,0.091394574,-1.05918513,-1.988937185,-0.103093911,0.120605407,0.08625768,-0.072476489,0.045197593,0.104605888,0.052287507,0.13050164,-0.742641368,-1.375728891,-1.807678091,-2.170196278,2.021030271,1.544179607,-7.890401495,-9.506108986,-7.658956085,-5.69568721,-9.64809304,-6.943162155,-5.025148263,-3.065102733 -4698,R271I,0.010065736,-0.078285532,-0.034646696,-0.070307373,-0.15856105,-0.052544264,0.032137289,-0.012005817,0.007689382,-0.125794643,-0.03077642,-0.053362808,-0.015930583,-0.081459925,-0.059154821,-0.131920975,-0.185201124,1.502699513,2.291849633,-5.916934647,-7.631395226,-6.042563309,-5.947433205,-5.631646568,-4.331634926,-4.784953834,-2.92474801 -4699,R271H,-0.053557452,0.040878127,0.000275945,0.003427352,-1.350593911,0.082589086,-0.042915865,-0.064199038,-0.010769301,0.085509838,-0.003753584,0.078492597,-0.077940708,0.038545243,-0.031690539,-1.118674093,-1.582513728,0.603186059,1.334859372,-7.503212657,-8.513963829,-7.804603531,-6.758643509,-8.311483719,-6.127368698,-4.790249114,-3.254757586 -4700,R271K,-0.109719671,-0.047148928,-0.035107645,-0.066985803,-0.109377387,-0.022709348,-0.178199868,-0.041239473,-0.020436185,-0.00192166,-0.092376195,-0.025848002,-0.044367287,-0.073026757,-0.060944848,-0.050843892,-0.167910882,1.546473607,2.938183126,-6.330341576,-6.112701675,-9.364824287,-5.297240669,-5.855620087,-5.021321159,-4.247444078,-3.368214527 -4701,R271M,0.076466785,0.038253897,0.07728792,0.045271474,-0.04327186,0.040726457,0.071584718,0.081348851,-0.015404124,0.060897499,0.015610295,0.062344777,0.092231062,0.038917537,0.051625411,-0.003208796,-0.083334923,1.287604928,2.657464261,-7.114774141,-8.163379059,-8.568783867,-6.822238014,-6.738262436,-5.281207329,-6.019360919,-4.424314058 -4702,R271L,0.026058122,0.018060137,0.050181815,0.025077868,-0.001571258,-0.029165316,0.007923366,0.044192877,0.005769753,0.010538563,0.025581711,0.025023446,0.075340183,0.008441458,0.041714278,0.000986355,-0.00412887,1.116072357,2.504805661,-1.799730977,-2.051547043,-2.396899033,-1.882192764,-1.626864304,-1.041151741,-1.72088234,-2.309896272 -4703,R271N,0.012852291,-0.038103534,0.009957718,0.04613864,-0.209096776,0.019999018,-0.08383116,0.109535742,-0.046271186,0.018687419,-0.094894486,-0.030394409,0.050309845,-0.006356591,0.098633871,-0.14494547,-0.273248082,1.325286068,2.206595872,-9.632101596,-9.66559713,-10.32803674,-9.839833244,-9.728282806,-8.598758057,-4.211968324,-1.097126517 -4704,R271Q,-0.028169395,-0.015179039,-0.009641953,0.050044658,-0.152919851,-0.050078149,-0.063873268,0.007534479,-0.075424159,-0.001365941,-0.028992137,-0.010790876,-0.00849303,0.036075886,0.06401343,-0.106998744,-0.198840957,1.266986491,2.216815181,-6.820826326,-7.568268387,-8.348463371,-7.45922242,-6.076279396,-4.651898056,-3.495614264,-1.934841334 -4705,R271P,-0.012033445,0.029142241,0.03268523,-0.223549576,-1.75957902,-0.082940006,-0.011948517,-0.012118372,-0.026342761,0.048983174,0.009301308,0.020216348,0.045154112,-0.020126558,-0.426972594,-1.667864802,-1.851293237,0.708691427,1.313370867,-10.06670939,-11.08811894,-11.11399947,-9.75744091,-9.783883804,-8.590103844,-5.584129107,-3.962890861 -4706,R271S,0.012450007,-0.006182243,0.018134179,0.026403676,-0.48529,-0.063183739,0.008724086,0.016175928,-0.048366552,-0.001365941,-0.010998544,-0.020953105,0.057221462,-0.007062459,0.05986981,-0.38183499,-0.58874501,1.008784361,1.620262593,-5.116396861,-4.569901917,-6.161299492,-5.654759491,-5.091296501,-4.104726906,-3.35408581,-1.697916207 -4707,R271T,0.004298607,0.006811419,-0.001557805,-0.046779843,-0.219194195,-0.06186127,-0.02900926,0.037606473,-0.018951604,0.032929159,-0.019306321,0.024165978,-0.027281588,-0.003908304,-0.089651382,-0.163111481,-0.275276908,1.476887223,2.27405069,-6.450218137,-7.004662621,-6.54497789,-7.960066513,-5.270193359,-5.4711903,-5.047270664,-2.260794497 -4708,R271W,-0.024721688,0.00600562,-0.031350643,-1.490238747,-1.8522165,-0.198879457,-0.04065369,-0.008789686,-0.060385395,0.054957431,-0.042946192,0.059190133,-0.121891418,-1.319147255,-1.661330239,-1.810507381,-1.893925619,3.212294552,2.370714614,-10.36453822,-10.84102312,-10.85495948,-10.09110312,-11.12797205,-8.907633347,-7.571739833,-5.997125433 -4709,R271V,-0.027211632,-0.005220443,-0.007197276,0.019706284,-0.323375253,-0.068569499,-0.049306079,-0.005117185,0.043408853,0.003236892,-0.013677778,-0.001679181,-0.012715371,0.022568983,0.016843585,-0.188333885,-0.45841662,1.365952568,2.140208431,-5.672000456,-6.896708817,-5.920889824,-6.075924133,-5.544536858,-3.92194265,-5.151729557,-1.756220021 -4710,R271Y,-0.044216372,-0.021677394,0.001115491,-1.608765727,-1.895297567,-0.115743672,-0.082757017,-0.005675726,0.021145365,-0.012310064,-0.031044724,0.000626893,0.001604089,-1.505728872,-1.711802582,-2.109438607,-1.681156527,1.112417458,0.752629521,-11.42812937,-14.21516967,-12.51848643,-9.646871193,-12.10104384,-8.659075706,-6.838377007,-4.80878227 -4711,N272A,-0.003206595,0.037253148,0.025637894,0.018814057,-1.503449934,-0.022050348,0.010751236,-0.017164425,-0.301029996,0.064906639,0.009599657,0.003844158,0.04743163,0.047135961,-0.009507847,-1.47961599,-1.527283878,0.567443353,1.315076988,-8.695042061,-11.65709365,-9.060844521,-7.311714417,-7.767588364,-7.677969353,-6.342204122,-1.157574364 -4712,N272C,0.002339129,0.005863978,-0.009496733,-0.94739273,-2.535906828,0.012800595,0.017364705,-0.012686447,-0.118689787,-0.033517783,0.045245739,-0.058148515,0.03915505,-0.347782536,-1.547002923,-1.746234622,-3.325579034,1.575476365,1.417009194,-11.36816614,-13.24986112,-11.47356143,-9.689869186,-11.24678302,-11.18075592,-8.084502696,-2.765288974 -4713,N272E,-0.02002424,-0.015086658,-0.013248159,0.018676339,-1.593646034,-0.009244002,-0.047597421,0.007548941,-0.280615531,-0.007314226,-0.022859089,-0.00418698,-0.022309337,0.014077766,0.023274911,-1.482200926,-1.705091142,0.669185008,1.319673223,-6.596958974,-9.389962364,-5.257612793,-6.011967003,-6.122048187,-6.203204521,-6.709522435,0.28369715 -4714,N272D,0.035129802,0.025773968,0.016224041,0.050486015,-0.07933293,-0.076551483,0.045420223,0.024839381,-0.302098371,0.027903636,0.0236443,0.019622867,0.012825215,0.074494263,0.026477767,-0.079926394,-0.078739465,1.186148441,2.301465198,-4.28526559,-4.910842033,-4.728871506,-3.110345131,-4.544304619,-4.131964661,-3.819189542,0.428275896 -4715,N272G,-0.025887632,0.00344386,-0.021010355,0.029519222,-1.639791387,-0.05851241,-0.04360787,-0.008167393,-0.216412934,0.044679839,-0.03779212,-0.001513867,-0.040506843,0.06660418,-0.007565737,-1.507175701,-1.772407073,0.406653148,1.30743929,-9.537358505,-12.81583868,-8.477954239,-8.924373802,-9.109165482,-8.359460327,-7.270035837,-2.630576544 -4716,N272F,-0.009782553,-0.209506246,-1.595318566,-1.95613561,-2.708675753,0.009510414,0.029612461,-0.049177566,0.267462648,-0.000815041,-0.41819745,-1.487009134,-1.703627997,-1.839135604,-2.073135616,-2.11939509,-3.297956416,3.792704616,2.289483172,-12.1430203,-14.25903537,-12.81730621,-10.62202444,-10.01471681,-13.00201865,-8.506450573,-3.454225242 -4717,N272I,-0.078710899,0.01136864,-0.211616155,-1.575199462,-2.488615886,0.018040012,-0.033071168,-0.124350629,-0.071355909,0.004860737,0.017876542,-0.051104157,-0.372128153,-1.295269961,-1.855128962,-2.221793102,-2.75543867,0.785261256,0.731521154,-12.72876414,-15.03703909,-15.9364978,-12.71388398,-10.22538979,-9.731010071,-8.524841006,-2.056620914 -4718,N272H,-0.012431018,-0.001819407,-0.014202944,-0.456683617,-1.782516552,-0.033910594,-0.001823609,-0.023038426,-0.258442552,0.003956111,-0.007594924,-0.059236292,0.030830405,-0.140416867,-0.772950367,-1.825126063,-1.739907041,1.115358893,1.328920202,-8.365798621,-10.89027876,-9.74103804,-6.736983955,-7.742383438,-6.718308914,-6.747235564,-3.013295662 -4719,N272K,-0.053729834,0.027542814,-0.898911058,-1.700728051,-2.789976144,-0.033025672,-0.064105402,-0.043354266,-0.158506084,0.046047448,0.009038179,-0.500343666,-1.29747845,-1.678952705,-1.722503397,-2.331598096,-3.248354192,1.750991385,0.862109468,-8.066130597,-10.49394318,-6.767904617,-8.511230942,-8.754548576,-5.803025665,-6.69223581,-1.21357071 -4720,N272M,0.018310811,0.089819225,-0.398696265,-1.692564294,-2.471224247,0.037609638,0.060640152,-0.02401853,-0.386174189,0.099011007,0.080627443,-0.119710496,-0.677682033,-1.563458836,-1.821669752,-2.174711542,-2.767736951,1.228820794,0.756571427,-12.65838694,-15.57863517,-12.26107841,-14.186439,-8.2410373,-13.0247448,-8.516267323,-2.799053672 -4721,N272L,-0.045992358,0.00707696,-1.134172614,-1.988657821,-2.585728822,0.047406466,-0.010555025,-0.08142969,-0.134487495,0.028440323,-0.014286403,-0.811309011,-1.457036217,-1.829864838,-2.147450803,-2.378969637,-2.792488006,2.567080043,1.312241153,-12.00424889,-14.75264967,-11.47689108,-13.41644108,-9.604746033,-10.77051659,-7.727594986,-2.68970763 -4722,N272Q,-0.021183942,0.007917307,-0.003577385,-0.146648213,-1.972910607,-0.00177953,-0.002294349,-0.040073535,0.037788561,0.040609966,-0.024775352,-0.00741531,0.000260541,0.03210432,-0.325400746,-1.906069155,-2.039752058,0.771172884,1.304565502,-7.983628148,-11.43663958,-6.690371132,-7.491059898,-6.250054497,-8.050015633,-6.202955085,-1.394818348 -4723,N272P,-0.004011905,-0.28622861,-1.515232467,-2.045408474,-2.718812164,0.003552744,0.016703895,-0.024727705,0.104735351,-0.046707533,-0.525749687,-1.511168549,-1.519296384,-1.926513935,-2.164303013,-2.529797711,-2.907826617,0.67957569,0.037030564,-10.15122138,-11.65572986,-11.56747823,-10.09458411,-9.287427719,-8.150886986,-6.998781227,-2.779802045 -4724,N272S,-0.030252533,0.006409692,-0.010635249,0.015454115,-0.347253846,-0.009283106,-0.025415372,-0.035089694,-0.103980384,0.030051209,-0.017231825,-0.005042993,-0.016227505,0.043702636,-0.012794407,-0.2560418,-0.438465892,0.574596769,1.455280059,-6.064795747,-8.025879478,-5.58520314,-5.269724586,-6.465253693,-4.977917839,-5.12417719,-1.665140482 -4725,N272R,-0.002127541,0.034472437,-0.283097455,-1.668219613,-2.616846506,0.005906767,0.02528944,-0.029544521,-0.290199148,0.056258449,0.012686424,-0.065492516,-0.500702393,-1.406960917,-1.929478309,-2.263726291,-2.96996672,1.141535476,1.839582957,-9.662847717,-12.27937914,-11.24554509,-9.174606445,-9.177989426,-6.436718491,-6.549501494,-1.164768213 -4726,N272T,0.011714433,0.023926204,0.023053279,0.040536066,-0.465793446,-0.04744578,0.013014786,0.010414079,-0.092754053,0.039889186,0.007963221,0.018384798,0.027721759,0.044706097,0.036366035,-0.365006891,-0.56658,1.894592864,1.422241265,-8.943041521,-10.66430339,-8.499652092,-8.35925164,-8.629180397,-8.562820084,-7.563626579,-2.022385018 -4727,N272W,-0.05497461,-0.333984235,-1.849705707,-2.317536887,-2.795166843,0.007073101,-0.036185193,-0.073764027,-0.158506084,-0.080067381,-0.587901088,-1.830267801,-1.869143613,-1.992730204,-2.64234357,-2.302952914,-3.287380772,2.462272951,1.042175607,-12.0264918,-15.25028069,-12.42730246,-10.7327964,-9.337172928,-12.38490652,-8.728449888,-2.860228893 -4728,N272V,-0.006610544,-0.00452383,-0.0000178,-1.210801525,-2.225302873,0.012013821,0.023622985,-0.036844072,-0.196294645,0.028785686,-0.037833345,-0.026556523,0.026520982,-0.771736373,-1.649866676,-2.026441755,-2.42416399,3.881750222,2.131921798,-12.23092758,-13.89471132,-15.56721265,-11.65771252,-9.84912104,-10.18588039,-7.772656755,-2.357678512 -4729,N272Y,-0.019510772,-0.069067065,-1.26830666,-2.042277418,-2.942456395,0.041712855,0.028565985,-0.067587528,-0.298956987,0.013754116,-0.151888246,-1.154319565,-1.382293755,-2.025971137,-2.058583699,-2.482321883,-3.402590906,1.362315305,2.531412538,-10.42520367,-12.76730959,-11.2742899,-8.639717743,-9.128848457,-10.31585264,-8.021267678,-2.708028739 -4730,R273A,0.018505737,0.004479534,0.029985123,0.024175599,-0.007123175,-0.009816536,0.012780626,0.024230847,0.02162181,-0.017019972,0.025979039,-0.022359471,0.082329716,0.013357025,0.034994173,-0.049828471,0.035582121,1.477318857,2.287625184,-0.324098868,0.133507607,-1.223462738,-0.319495857,0.11903949,-0.33008284,-0.353881067,1.096669928 -4731,R273C,-0.026973725,0.027862283,0.007180047,0.016976524,-0.193968327,-0.010930371,-0.055475495,0.001528046,-0.020744321,0.056686897,-0.000962331,-0.014319152,0.028679245,0.016310857,0.01764219,-0.150956928,-0.236979726,1.425311276,2.2410108,-7.167574728,-7.076200127,-7.268829887,-7.843083702,-7.002174461,-6.647585464,-6.742537716,-5.801072034 -4732,R273E,0.042509079,0.04073606,-0.001431225,0.059097727,-0.007542683,-0.086908501,0.057661653,0.027356505,-0.027247856,0.088035565,-0.006563445,-0.028627429,0.025764979,0.090895074,0.02730038,0.025483111,-0.040568476,1.26322028,2.092326537,-1.247453065,-1.895240761,-1.791038689,-0.874153511,-0.461161278,-1.215671089,-1.461796718,0.13816734 -4733,R273D,0.062110096,-0.04360097,0.038240759,0.092570509,-0.138762232,-0.004715745,0.083363077,0.040857115,-0.02243195,-0.062786352,-0.024415588,-0.013229329,0.089710847,0.037521763,0.147619255,-0.165095325,-0.112429139,1.18809423,2.79001725,-3.393028859,-4.000329651,-3.473650543,-3.241805511,-2.818193207,-3.431165382,-2.414712372,-0.524166577 -4734,R273G,0.018874513,0.00628894,-0.011514123,-0.002030531,-0.083012415,-0.04991393,0.01869116,0.019057866,-0.000523036,-0.00063772,0.0132156,-0.037623271,0.014595026,0.015567673,-0.019628735,-0.096377486,-0.069647343,1.485328664,2.409680627,-3.013665625,-2.946638252,-3.409270218,-3.051954811,-2.805581291,-2.854883553,-2.715768983,-1.490549708 -4735,R273F,0.063963341,0.014845793,0.00685101,0.018896259,-0.126650445,-0.128652891,0.074732887,0.053193794,0.057211761,0.015036241,0.014655345,-0.014319152,0.028021171,-0.012578709,0.050371227,-0.153208431,-0.100092459,1.441242131,2.390395704,-7.603258415,-7.076874313,-8.154137032,-9.055799377,-7.987339874,-5.742141479,-5.469725324,-4.472452335 -4736,R273I,0.111033003,0.033559082,0.053260871,0.105435155,-0.016893345,-0.083017406,0.095037074,0.127028931,-0.03444175,-0.030721249,0.097839412,-0.071357653,0.177879395,0.071742177,0.139128132,-0.106098638,0.072311949,1.220591271,2.379905549,-5.222427307,-5.197386101,-5.945623978,-5.745323364,-3.87235141,-5.351451683,-4.220002071,-2.664720253 -4737,R273H,0.034104136,-0.04540119,-0.023436111,-0.031029955,-0.019283043,-0.068105809,0.042492322,0.025715949,0.015712854,-0.072489785,-0.018312594,-0.091393001,0.04452078,-0.084162773,0.022102864,-0.083069237,0.044503151,1.274568405,2.267189528,-3.642267139,-4.396216843,-3.648623276,-3.979755135,-3.408601692,-2.778138748,-4.111279923,-2.232376773 -4738,R273K,-0.018940675,0.021323883,0.003095834,0.051887744,-0.048172532,-0.018099133,-0.019516814,-0.018364535,-0.060835754,0.08374131,-0.041093545,-0.034810628,0.041002296,0.047902039,0.055873448,-0.059058633,-0.037286431,1.280462821,2.298336825,0.138922319,0.422260406,0.198594124,-0.627759903,0.448933121,0.252583847,-0.0760093,0.00500682 -4739,R273M,0.000195402,-0.034678861,-0.018451324,-0.007985132,-0.104095374,0.015127633,0.017280653,-0.01688985,-0.111131368,-0.025329743,-0.044027978,-0.004546137,-0.032356511,-0.001583324,-0.014386939,-0.103163636,-0.105027112,1.339676866,2.420110777,-4.794306494,-5.157402779,-5.705244652,-5.129123802,-3.702047157,-4.277714081,-4.870563985,-3.23376571 -4740,R273L,0.048991711,0.031334926,0.01400842,0.025461197,-0.034706069,-0.053244398,0.052857643,0.045125779,-0.011952847,0.025880822,0.03678903,-0.049202181,0.07721902,-0.006813653,0.057736046,-0.080318666,0.010906528,1.220664437,2.171555293,-3.538246948,-4.324511459,-4.415751724,-3.384470009,-2.182647354,-3.383854195,-2.76941412,-1.416059422 -4741,R273N,0.035933452,-0.001023638,-0.061501362,0.003042483,-0.062109925,-0.022501899,0.061850529,0.010016375,-0.023322237,-0.028218374,0.026171099,-0.096436891,-0.026565832,0.000386268,0.005698697,-0.079105995,-0.045113855,3.342225137,1.943408792,-3.882121341,-4.422082245,-2.714630783,-4.93126548,-4.319423698,-3.023204498,-3.904892764,-1.809012643 -4742,R273Q,0.067728353,0.018543393,0.016264485,0.028926993,0.004298831,-0.110088715,0.045506381,0.089950325,0.030393712,0.015333195,0.02175359,0.011506787,0.021022183,0.044148916,0.01370507,0.016085246,-0.007487585,2.922372547,1.92541614,-0.342386234,-0.966286034,-1.031754082,-0.149141594,0.530850739,-0.095600197,-1.795453146,-0.432433112 -4743,R273P,-0.026607738,-0.068729342,-1.289282734,-1.999787502,-2.463472371,-0.06599882,-0.016948346,-0.03626713,-0.005614903,0.006094077,-0.14355276,-1.027367494,-1.551197973,-1.930384197,-2.069190807,-2.221105441,-2.705839301,1.149456302,2.659380698,-3.67158058,-4.099583748,-4.729502495,-3.982655914,-4.298177094,-1.24798365,-3.164739839,-0.987750462 -4744,R273S,0.035589459,0.014387298,0.033143758,0.030517715,-0.030727435,-0.033809835,0.041534517,0.029644401,0.018593112,0.03647879,-0.007704195,0.002953752,0.063333763,0.027577486,0.033457944,-0.039289698,-0.022165171,1.286724075,2.519362906,-2.617100127,-2.480164375,-2.89774894,-3.081988319,-2.900401825,-1.725197174,-2.881406247,-1.251553269 -4745,R273T,0.048148572,0.006090244,0.035820394,0.038846351,-0.017076403,-0.060537325,0.055513577,0.040783567,0.070950859,-0.003544229,0.015724716,-0.025905408,0.097546196,0.02552207,0.052170631,-0.03004566,-0.004107145,1.243379167,2.524836693,-2.322740489,-1.462617592,-3.38855645,-3.132381645,-2.608725479,-1.02142128,-2.270420623,-1.221977713 -4746,R273W,-0.010066024,-0.017464948,-0.021480288,-0.04342646,-0.143334305,-0.06201426,-0.015919642,-0.004212405,-0.009055515,-0.028625654,-0.006304242,-0.096827251,0.053866675,-0.052361616,-0.034491304,-0.183777352,-0.102891257,1.58062497,2.248609267,-7.053531654,-7.135460411,-7.032980736,-7.772044701,-7.275353966,-6.051818459,-5.658644195,-4.516170188 -4747,R273V,0.027985072,-0.01703843,-0.020673321,0.01846637,-0.039767452,-0.047406937,0.037279353,0.018690791,0.047119062,-0.041464767,0.007387908,-0.057855183,0.016508542,-0.000282391,0.03721513,-0.089403067,0.009868164,1.464350687,2.471963602,-4.202275642,-3.872183746,-5.012561462,-4.823983635,-3.63109774,-3.671551628,-4.071774254,-1.526447816 -4748,R273Y,0.037664913,0.025705977,-0.006541016,0.030847416,-0.042931939,-0.008036299,0.06853355,0.006796276,-0.011712649,0.003082427,0.048329526,-0.081587284,0.068505253,-0.04050139,0.102196222,-0.123766447,0.037902569,1.430130987,2.273058002,-7.246611481,-7.059349777,-7.984315125,-8.628974342,-7.557939987,-5.002478172,-5.311325,-4.247454561 -4749,Q274A,-0.02754578,0.029658929,-0.021099838,-0.013000835,0.021095374,-0.015979021,-0.057881992,0.002790433,-0.008547971,0.042513639,0.016804219,-0.023122076,-0.019077599,0.034365293,-0.060366962,0.008090606,0.034100141,1.190771732,2.752532561,-1.102549677,-0.692565842,-1.990490845,-1.059884201,-0.953784889,-0.816022606,-2.101624955,3.595467112 -4750,Q274C,-0.034845223,-0.002839797,-0.018970994,-0.049068637,0.002516021,-0.065026096,-0.033543516,-0.03614693,0.067620669,-0.013867186,0.008187593,-0.029943453,-0.007998534,-0.005666043,-0.092471231,-0.046388114,0.051420156,1.24347922,2.443895057,-5.934735515,-6.250626595,-7.493432808,-5.16841536,-5.218411995,-5.542790817,-4.720510291,-0.703446822 -4751,Q274E,-0.089791423,-0.002434464,-0.031554087,-0.025829118,-0.05505396,-0.020936808,-0.081885061,-0.097697785,-0.025490469,0.019321257,-0.024190184,-0.003050122,-0.060058052,0.045272407,-0.096930642,-0.002373705,-0.107734214,1.228452329,2.731102576,-3.455788919,-2.901368851,-4.352871323,-3.208870003,-3.253070801,-3.562763618,-4.616312925,-0.82296096 -4752,Q274D,-0.057334306,-0.014953251,-0.025441746,-0.932921418,-1.901776732,-0.027662326,-0.024317016,-0.090351596,0.028291042,0.000484625,-0.030391127,-0.005872212,-0.04501128,-0.291156263,-1.574686573,-1.897705275,-1.905848189,1.343076584,1.346752705,-6.304823141,-6.880741699,-6.949713211,-5.481692154,-6.33057518,-5.881393463,-5.665175141,-1.331591637 -4753,Q274G,-0.073278271,0.008315531,-0.038020694,-0.026330595,-0.353408171,-0.003040376,-0.047722342,-0.0988342,0.034946225,0.002483058,0.014148003,-0.03166225,-0.044379137,0.008119975,-0.060781165,-0.256378787,-0.450437554,1.201104751,1.865490809,-5.492237659,-5.051880699,-5.329519737,-6.606426476,-4.633092804,-5.840268578,-4.229653161,-0.810727191 -4754,Q274F,-0.100230033,-0.081638334,-0.056645376,-0.117635813,-0.114884101,-0.002256167,-0.082589833,-0.117870233,0.016611891,-0.083907022,-0.079369645,-0.040424063,-0.072866689,-0.081685562,-0.153586063,-0.156704972,-0.07306323,1.586735144,2.344134907,-5.33403903,-7.459368454,-5.960101906,-3.904954262,-4.704722191,-4.64104834,-4.310036051,1.729366493 -4755,Q274I,-0.056472466,-0.028563113,-0.046709266,-0.041060762,-0.035070981,-0.041459156,-0.074108284,-0.038836648,-0.037166679,-0.01021364,-0.046912585,-0.005384877,-0.088033654,0.064419978,-0.146541501,-0.040970252,-0.029171709,1.247363549,2.50703257,-4.874457727,-5.506892487,-5.723455872,-4.735490074,-3.621865501,-4.784584702,-3.223416532,2.962734471 -4756,Q274H,-0.030290297,-0.019757025,-0.026608395,-0.042476731,0.015989086,-0.054399293,-0.045579048,-0.015001546,0.044899594,-0.007341955,-0.032172095,-0.009450763,-0.043766026,0.009391987,-0.094345448,-0.011627443,0.043605615,1.322667294,2.617897504,-1.999197383,-1.937262024,-2.233154129,-1.6519496,-2.210432175,-1.963188988,-2.831270886,-0.97008381 -4757,Q274K,-0.097588815,-0.005958817,-0.049797234,-0.07042327,-0.067261017,0.011097934,-0.081277432,-0.113900197,0.045364798,-0.052152205,0.040234571,-0.011845231,-0.087749237,-0.014451801,-0.126394739,-0.039445789,-0.095076245,1.371620235,2.509851789,-3.473255493,-3.997062271,-3.079362846,-3.620907188,-3.590927505,-3.078017654,-3.671408533,0.023799141 -4758,Q274M,0.00298749,-0.001099673,-0.024342928,-0.030054905,-0.001628293,-0.036004707,0.010584988,-0.004610008,0.089567635,0.015477611,-0.017676956,-0.011774894,-0.036910961,0.008115453,-0.068225263,-0.027887067,0.024630481,1.197209823,2.556279004,-5.265051324,-7.036064339,-4.402873131,-6.130845528,-3.379127281,-5.376346344,-4.261379713,1.444631923 -4759,Q274L,-0.046053971,0.004714327,-0.037633357,-0.036858275,0.004304036,-0.011092435,-0.053040133,-0.039067809,0.038772549,0.021537888,-0.012109234,-0.016169186,-0.059097528,0.020245785,-0.093962335,-0.005488021,0.014096092,1.190206942,2.541524194,-3.843356313,-4.811871841,-4.614285011,-4.275255737,-2.509185249,-3.006183723,-2.122647011,3.930502995 -4760,Q274N,-0.02165357,0.036975346,0.012456123,0.001337287,-0.138912435,-0.071280642,-0.003242977,-0.040064163,0.021133337,0.010094737,0.063855954,0.013094889,0.011817357,0.030782933,-0.028108359,-0.15591688,-0.121907989,1.365674417,2.205348155,-5.397968929,-6.603283012,-5.025456116,-5.368490746,-5.779229668,-4.213385101,-6.077844621,-0.941826566 -4761,Q274P,-0.024265742,-0.017481211,-0.04224768,-0.609354677,-1.761989201,-0.049787232,-0.042886424,-0.005645059,0.027540737,-0.013510811,-0.02145161,-0.032725221,-0.051770138,-0.138544233,-1.08016512,-1.783378427,-1.740599974,1.037431834,1.327565316,-6.423183339,-6.503982506,-8.183305969,-6.722671806,-5.413595261,-5.292361153,-4.452036092,-0.189699885 -4762,Q274S,-0.018790166,-0.001162914,-0.035876874,-0.029355453,-0.036141202,-0.021899362,-0.005679948,-0.031900383,0.005164422,0.007236481,-0.009562308,-0.019284496,-0.052469252,0.017098546,-0.075809452,-0.045265221,-0.027017183,1.312288508,2.527666673,-5.320170287,-5.967720619,-5.264715027,-5.101610611,-5.610961014,-4.655844162,-4.943891226,0.208434426 -4763,Q274R,-0.032040683,0.003527758,-0.01055972,-0.034706796,-0.067524796,-0.038870853,-0.027184497,-0.036896868,0.054528119,-0.008997674,0.01605319,-0.011620107,-0.009499332,-0.008973753,-0.060439838,-0.087385892,-0.047663699,1.32176643,2.289655704,-3.29577074,-3.902821381,-4.443630898,-3.174662544,-2.990900902,-1.966837975,-4.849690658,0.818602934 -4764,Q274T,-0.007163309,0.00249145,-0.041306344,-0.044343234,-0.039528661,-0.015292961,-0.007602542,-0.006724075,0.033595276,-0.020531483,0.025514382,-0.030299128,-0.052313559,-0.042113233,-0.046573235,-0.076353325,-0.002703996,1.322048357,2.325197464,-4.028962235,-4.355695297,-3.95744902,-3.95602137,-3.456609756,-4.419035728,-2.975386199,2.408775785 -4765,Q274W,-0.036701979,0.010252567,-0.028438751,-0.034740095,0.022395674,-0.017440202,-0.038611406,-0.034792552,0.027190982,-0.002678588,0.023183722,-0.040088765,-0.016788737,-0.0316739,-0.03780629,-0.009562859,0.054354207,1.338230023,2.622232115,-6.145883347,-5.344316948,-9.670859161,-5.126168312,-5.833386948,-4.754685364,-4.220553165,-0.384673811 -4766,Q274V,-0.012650797,0.002679929,-0.060767977,-0.03978115,0.017103224,0.00667329,-0.020314444,-0.004987149,0.032997487,-0.010302667,0.015662525,-0.067999763,-0.053536191,-0.006491584,-0.073070715,-0.022713142,0.05691959,1.424047875,2.571789416,-3.026013599,-3.444137436,-3.467461472,-3.188999763,-2.604184174,-2.425285149,-2.58519043,3.540017328 -4767,Q274Y,0.031832519,-0.05278257,-0.009744519,-0.011870995,-0.092507326,-0.060205066,0.045408826,0.018256212,-0.014248757,-0.125535668,0.019970528,-0.092157132,0.072668095,-0.029822186,0.006080196,-0.131773026,-0.053241625,1.396540044,2.246416119,-3.919916275,-3.779225685,-4.308113823,-3.395153397,-4.385569664,-3.731518806,-4.778929562,0.36715087 -4768,I275A,-0.0000557,-0.001879209,-0.907259057,-1.897835977,-2.439738277,-0.018365913,-0.000172589,0.0000611,0.037939416,-0.005602735,0.001844318,-0.466695516,-1.347822597,-1.756253336,-2.039418618,-2.210942674,-2.66853388,2.926105798,1.749676944,-8.628404227,-5.871428986,-9.074587952,-13.91504097,-6.800934921,-7.480028305,-6.08182364,-4.321669498 -4769,I275C,0.001317929,0.010862874,0.065062974,-0.81046375,-1.816160071,-0.026790508,0.007562132,-0.004926274,0.065763425,0.023151353,-0.001425606,0.051474385,0.078651562,-0.164941184,-1.455986316,-1.959578584,-1.672741558,1.046489202,1.313182387,-11.61364077,-8.487767586,-13.36587415,-16.1395902,-9.143384575,-10.93158732,-7.360391935,-4.994998004 -4770,I275E,-0.024310809,-0.817907861,-1.858319974,-2.162027079,-2.747169622,-0.006516704,0.028864921,-0.077486539,0.102833455,-0.526919698,-1.108896023,-1.843609066,-1.873030881,-1.886422176,-2.437631982,-2.517202773,-2.97713647,3.436198511,1.606141828,-12.68330055,-10.15234972,-12.66823276,-19.09430688,-10.05683628,-11.44477711,-8.028282977,-6.187012801 -4771,I275D,-0.027642266,-1.349309912,-2.02553685,-1.876731713,-2.93899551,0.020008385,0.01238098,-0.067665512,0.059753875,-1.345933569,-1.352686255,-2.443262987,-1.607810713,-1.963197352,-1.790266073,-2.718916686,-3.159074334,0.036634672,-0.827690447,-14.49114027,-11.14731986,-15.0238857,-21.51391459,-11.50844238,-13.26213882,-8.649820738,-7.07168951 -4772,I275G,0.007728294,-0.690030128,-1.916838322,-2.021057465,-2.711967313,-0.016715279,0.018808524,-0.003351936,0.064603335,-0.391837756,-0.988222499,-1.981821937,-1.851854706,-1.991842534,-2.050272395,-2.642826517,-2.781108108,1.172262815,-0.116360483,-12.18518138,-9.228764404,-13.14955711,-18.47198851,-9.461589577,-10.61400731,-7.234858164,-4.634008868 -4773,I275F,-0.022057005,0.046488095,0.071046295,0.133818796,0.08968222,-0.096373052,-0.037085979,-0.007028031,0.042079969,0.119099186,-0.026122997,0.193165906,-0.051073317,0.192317297,0.075320294,0.16537878,0.01398566,1.031816043,3.195791291,-6.495315529,-3.968827751,-6.058925987,-7.151225693,-8.100083076,-7.197515137,-4.969172221,-2.749201696 -4774,I275H,-0.010020651,-0.119131267,-1.553084219,-2.044714542,-2.541811455,-0.018157193,0.023593887,-0.043635189,0.063663851,0.005844477,-0.24410701,-1.242420715,-1.863747722,-1.928686501,-2.160742583,-2.258437103,-2.825185807,2.972801913,1.507527499,-10.2421026,-4.681064903,-10.04069859,-18.11421626,-8.109189835,-10.26534341,-4.985633178,-3.099209262 -4775,I275K,-0.091123242,-1.393714747,-2.463404273,-2.320716363,-2.755343908,-0.055048434,-0.093271056,-0.088975427,0.063614058,-1.299840845,-1.487588649,-1.950012232,-2.976796313,-1.895915329,-2.745517397,-2.526695927,-2.983991889,4.002667298,1.808555359,-14.08305897,-11.37246316,-14.46673823,-20.33527316,-10.65150823,-13.58931207,-8.877430577,-7.530862831 -4776,I275M,0.005011609,0.01145538,0.008364801,0.068967406,-0.220181281,-0.060829523,-0.020612242,0.030635459,0.03674778,0.02014419,0.002766569,0.0398076,-0.023077999,0.083741608,0.054193204,-0.146445688,-0.293916874,1.396122805,2.24667422,-5.816622015,-4.912725746,-6.344098686,-7.705639114,-5.591704826,-4.528941704,-5.161657537,-1.90397913 -4777,I275L,0.056018095,0.049227169,0.089926485,0.112805758,-0.126616109,-0.05108165,0.057994493,0.054041696,0.074081672,0.030150813,0.068303525,0.125666109,0.05418686,0.117795974,0.107815541,-0.077256054,-0.175976164,1.271819585,2.468221541,-4.506190892,-3.042512505,-5.864920906,-5.910533096,-4.204286324,-3.50870163,-4.292800442,-1.17338686 -4778,I275N,-0.071911453,-0.935497664,-2.016707842,-1.891400986,-2.476543529,0.030376371,-0.000395917,-0.143426988,0.109271742,-0.578055203,-1.292940125,-2.201354444,-1.83206124,-1.721288809,-2.061513163,-1.999886888,-2.953200169,1.426804057,-0.070778581,-13.18685235,-9.91385199,-15.78229115,-19.18212263,-10.20297526,-10.85302074,-7.708568363,-5.562787293 -4779,I275Q,0.013188595,-0.723883319,-2.151574516,-2.412943844,-2.642484156,0.02191641,0.076791279,-0.050414089,0.092882524,-0.328658888,-1.119107749,-2.393803623,-1.909345409,-1.670699939,-3.155187748,-2.192336067,-3.092632244,0.160303953,-0.472849441,-12.23651223,-8.633685295,-12.57918719,-20.67984286,-8.843507675,-10.44633812,-6.903414712,-5.287203797 -4780,I275P,0.022229713,-1.405739811,-1.922166446,-2.097080973,-3.019296726,-0.010203057,0.041431813,0.003027612,0.089777771,-1.311993782,-1.499485839,-1.944436403,-1.899896489,-1.93289185,-2.261270096,-2.77293207,-3.265661382,-0.031497897,-0.792920582,-13.22762707,-11.0939675,-13.88031013,-17.90375451,-11.07412482,-12.18597839,-9.172198158,-8.156429405 -4781,I275S,0.031733741,-0.568478224,-1.846610425,-2.225655363,-2.732310421,-0.017603403,0.046700369,0.016767113,0.060075475,-0.296687048,-0.840269399,-1.912359458,-1.780861392,-2.034353814,-2.416956911,-2.530435838,-2.934185004,1.090730298,-0.061691949,-11.79798542,-8.561685974,-13.64867404,-16.68234362,-9.443138817,-10.65408466,-7.81536612,-6.119520047 -4782,I275R,0.016134171,-1.351642881,-1.860747491,-2.17145896,-2.93873551,-0.003586253,0.025825478,0.006442864,0.044545941,-1.337358452,-1.36592731,-1.897353209,-1.824141772,-2.182074862,-2.160843058,-2.53202885,-3.345442169,0.176498264,-0.797088182,-15.21142708,-10.38273331,-15.54736574,-24.54202978,-11.6608839,-13.9241227,-9.663760142,-9.382515756 -4783,I275T,0.001398308,0.019620932,-0.01224561,-1.429135768,-2.361641829,0.005331054,0.020080305,-0.01728369,0.047477585,0.017967398,0.021274466,0.059026498,-0.083517718,-1.129714466,-1.728557069,-2.172675511,-2.550608147,2.16250571,1.437562065,-10.39823908,-7.162806358,-11.00073662,-15.66569762,-8.241904968,-9.920049828,-7.206598376,-4.165364197 -4784,I275W,0.001324006,0.065306809,-0.727406672,-2.138034597,-2.362077217,-0.024013261,-0.001442086,0.004090097,0.066214352,0.096664648,0.03394897,-0.282119518,-1.172693826,-1.661238384,-2.61483081,-2.229871074,-2.49428336,1.056467561,0.719535757,-13.23391374,-10.38550916,-13.62061644,-16.68403116,-12.36211575,-13.11729621,-9.206607206,-8.422806375 -4785,I275V,0.049367068,0.025095562,0.074328659,0.057454615,-0.044125186,-0.011119292,0.041209568,0.057524567,0.057081464,-0.003575052,0.053766175,0.070909654,0.077747664,0.026311362,0.088597868,-0.028520841,-0.059729531,1.22798405,2.501998941,-3.587860696,-3.277573555,-4.585765793,-3.631633484,-3.721163239,-2.723167412,-3.268839807,-1.669670789 -4786,I275Y,-0.011969448,0.005181589,0.015867115,-0.10169401,-1.614571656,-0.10473864,-0.004145893,-0.019793002,0.082529717,0.00209299,0.008270188,0.002341216,0.029393014,0.134580382,-0.337968402,-1.501432742,-1.72771057,0.613126077,1.314897246,-10.33422766,-5.585998665,-10.01471344,-13.87063116,-10.76400658,-11.43578845,-6.805769308,-5.794613976 -4787,A276C,-0.003691325,-0.007567267,-0.034851925,-0.013809043,-0.299150607,-0.01239783,0.006958269,-0.014340919,-0.002813853,0.002945354,-0.018079888,-0.059616487,-0.010087362,-0.046716463,0.019098377,-0.201741159,-0.396560055,1.395151041,2.09388478,-8.902840063,-9.479266327,-7.659302391,-8.794620659,-9.264240295,-9.316770645,-7.459460713,-6.985155437 -4788,A276E,0.025743793,-0.018260546,-0.008491644,-0.056446056,-0.779277688,-0.094396934,0.012542414,0.038945171,0.059615667,0.001391735,-0.037912826,-0.059745166,0.042761879,-0.083656376,-0.029235736,-0.666112974,-0.892442402,1.22661298,1.577312765,-5.658824867,-5.103459999,-5.0052481,-5.711222237,-5.203573029,-7.270620972,-4.807635564,-3.873384123 -4789,A276D,0.020969804,-0.022287445,-0.026263375,-0.107828254,-1.550481094,-0.081249362,0.015420287,0.026519321,0.062400544,-0.014465132,-0.030109758,-0.067107908,0.014581159,-0.053294243,-0.162362264,-1.76720407,-1.333758117,0.696574994,1.307969311,-8.536827275,-7.963535721,-6.846053658,-9.227985634,-8.780190598,-9.866370766,-7.505735726,-7.043619969 -4790,A276G,0.015998185,-0.004739643,-0.000991138,-0.002452283,-0.344260545,-0.082679548,-0.006600998,0.038597367,0.009483158,0.017718156,-0.027197441,0.00971477,-0.011697046,0.000716755,-0.00562132,-0.25409208,-0.434429009,1.344671111,1.996269239,-6.677811031,-8.839652237,-4.319663765,-6.971304123,-6.513882324,-6.744552704,-4.738435478,-1.620594889 -4791,A276F,-0.00579526,0.034680023,-0.010399528,0.010663297,-0.088089711,-0.038445528,-0.016242236,0.004651716,0.014163051,0.067633149,0.001726896,-0.013003257,-0.007795799,0.006005944,0.015320649,-0.083169194,-0.093010228,1.475690292,2.479203001,-10.39051915,-11.30129021,-8.536359917,-10.83515689,-10.43867031,-10.84111842,-8.262831524,-7.646493721 -4792,A276I,-0.029396546,-0.047192387,-0.074074485,-0.018130476,-1.478838915,-0.024612554,-0.013915247,-0.044877844,0.045984764,-0.086842047,-0.007542726,-0.067926817,-0.080222153,-0.021264741,-0.014996211,-1.368582815,-1.589095014,1.06508445,1.370726763,-6.875732956,-6.111890869,-5.488025177,-6.890523537,-7.909661697,-7.978563499,-5.669073616,-5.408171702 -4793,A276H,0.066314329,0.004690145,0.021401821,0.013457665,-0.0692059,-0.067168164,0.05521446,0.077414198,0.031627947,0.027535383,-0.018155094,0.032276724,0.010526917,0.016713293,0.010202036,-0.042233709,-0.09617809,1.237293081,2.427101362,-8.157183571,-8.388799324,-5.496337654,-8.723345573,-8.534674171,-9.642761131,-6.118951145,-5.34031814 -4794,A276K,0.038514898,0.052377366,0.015396273,0.083233687,0.049749611,0.018550545,0.046471178,0.030558617,0.028856528,0.07043335,0.034321382,0.055845725,-0.02505318,0.089300153,0.07716722,-0.025887935,0.125387156,1.128780973,2.548236946,-5.238360808,-4.838803505,-4.47796521,-5.829384232,-6.313576744,-4.732074348,-4.741975671,-3.927095871 -4795,A276M,0.006500373,-0.011872373,-0.028492106,-0.002898514,-0.06703507,-0.031781884,-0.012582429,0.025583174,0.000227273,-0.014443791,-0.009300955,-0.072805092,0.015820881,0.025625726,-0.031422754,-0.08250716,-0.05156298,1.453696401,2.540214447,-8.852096407,-8.859414886,-7.561922485,-9.116454453,-9.937026428,-8.78566378,-7.581251891,-6.985155314 -4796,A276L,-0.026929525,0.023245229,-0.002691207,0.015092895,-0.60293422,-0.040302901,-0.032863342,-0.020995707,0.018582493,0.061921507,-0.015431049,0.00567233,-0.011054743,0.01359942,0.016586369,-0.419863952,-0.786004487,1.159694675,1.688117924,-8.641094479,-8.296207008,-6.850186783,-8.505143593,-9.671116371,-9.882818642,-7.310066683,-6.501744154 -4797,A276N,0.043803224,0.039714012,-0.003578527,0.031504598,-0.616039405,-0.057705016,0.044111267,0.043495181,0.056400548,0.028926075,0.050501948,-0.001669805,-0.005487249,0.02189597,0.041113226,-0.483240069,-0.74883874,0.934615184,1.533127842,-5.949938057,-6.403395676,-4.080609993,-7.073294197,-5.843129684,-6.349260735,-5.295184735,-3.892485484 -4798,A276Q,0.109645403,0.005176798,0.022556586,0.064583418,-0.052753796,-0.035765871,0.110783838,0.108506968,-0.039126135,-0.02549561,0.035849206,-0.074390716,0.119503887,-0.008543919,0.137710754,-0.082898828,-0.022608763,1.20113283,2.204479806,-5.282344241,-5.346397568,-3.545718552,-5.531332977,-5.332157104,-6.656115005,-4.698797647,-2.569560457 -4799,A276P,-0.029075922,-0.48701323,-1.858788702,-1.984420003,-2.550635631,-0.023978329,-0.028431151,-0.029720693,0.003570411,-0.178639369,-0.79538709,-1.803928334,-1.913649069,-1.965548515,-2.003291491,-2.493029112,-2.60824215,0.953768091,-0.027403395,-7.298451497,-7.703163116,-4.954476936,-7.557997589,-7.498145004,-8.778474838,-6.735959052,-4.341025581 -4800,A276S,-0.012865522,-0.013179222,-0.039095185,0.004458084,-0.055652281,-0.025570239,-0.032499169,0.006768125,0.050462403,0.002448891,-0.028807334,-0.036569039,-0.041621331,0.004037329,0.004878839,-0.067147254,-0.044157308,1.227514043,2.331774979,-3.309900565,-4.604296677,-1.988797836,-3.335869514,-3.387108002,-3.233430794,-3.514746058,-2.416510928 -4801,A276R,-0.016676092,-0.005479847,-0.005058986,0.01800028,-0.022418982,-0.030124675,-0.033011009,-0.000341174,0.00981527,0.021385806,-0.032345499,-0.005686259,-0.004431713,0.009135644,0.026864915,-0.021828139,-0.023009825,1.385781746,2.661995835,-5.21939511,-5.943340881,-3.397115608,-4.55450222,-6.327174706,-5.874842133,-4.026266985,-2.066414889 -4802,A276T,-0.025133078,-0.011782298,-0.052611671,-0.027806374,-0.662173388,-0.096130542,-0.035941982,-0.014324173,0.011344964,0.006797724,-0.030362319,-0.044357333,-0.060866009,-0.016772424,-0.038840323,-0.485881938,-0.838464837,0.971463038,1.542808829,-5.080858821,-5.643151787,-3.654210106,-5.228705902,-4.96430304,-5.913923271,-5.225824281,-4.423774723 -4803,A276W,0.016703433,-0.018125741,-0.043425189,0.016847887,-0.913513533,-0.124920766,-0.043672462,0.077079327,-0.006940261,-0.020962672,-0.015288809,-0.07517128,-0.011679098,-0.015837769,0.049533542,-0.680649226,-1.146377839,0.904875215,1.450224448,-11.20906292,-11.97157731,-9.099558418,-11.70535574,-11.44111526,-11.82770786,-9.062415357,-10.01779928 -4804,A276V,-0.022864566,-0.001704977,-0.021373408,0.024532795,-0.172800332,-0.09194837,-0.042436969,-0.003292163,0.020686917,0.043150965,-0.046560919,0.007104803,-0.049851618,0.032108585,0.016957005,-0.131860047,-0.213740617,1.183900381,2.056735716,-4.337741606,-4.160464897,-3.174346199,-4.404865196,-4.663567055,-5.285464684,-4.012241135,-3.801842553 -4805,A276Y,0.022048751,-0.007780253,-0.016696146,-0.004028275,-0.088587526,-0.064410324,-0.01885355,0.062951052,-0.017966234,0.003176037,-0.018736543,-0.034489147,0.001096855,-0.055867707,0.047811157,-0.073288775,-0.103886276,1.494308414,2.495035222,-10.81876335,-11.2983976,-8.696537117,-11.23379858,-10.79633495,-12.06874851,-8.317371861,-7.646493721 -4806,E277A,0.020421894,0.010806663,0.006846637,-0.047800677,-0.084317277,-0.02851198,0.066287795,-0.025444008,0.037917889,-0.025057726,0.046671052,0.016532949,-0.002839675,-0.098409958,0.002808605,-0.103699025,-0.064935528,1.516860251,2.383603024,-1.702014723,-1.373267403,-2.575764549,-2.712879181,-0.798187286,-1.049975197,-1.727285766,-0.850259095 -4807,E277C,-0.023354652,0.015238709,0.011278123,-0.069879971,-0.615497464,0.02866313,0.053307966,-0.10001727,0.07734085,0.007183928,0.02329349,0.006716478,0.015839768,-0.113664281,-0.026095661,-0.440974436,-0.790020491,1.345469034,1.774962952,-7.944833446,-7.408907982,-9.013990585,-9.170588043,-6.423676826,-7.707003792,-7.74544551,-7.230363313 -4808,E277D,0.041215275,0.001462378,0.002400105,-0.0802448,-0.061959965,0.034811556,0.097130475,-0.014699926,0.04364712,-0.09314338,0.096068135,-0.044348494,0.049148703,-0.154193197,-0.006296403,-0.124601481,0.000681551,1.467679157,2.268601118,-0.787553625,-0.810155525,-1.127179634,-0.161002258,-0.788809044,-1.050621666,-1.497576332,-0.478717435 -4809,E277G,0.015894186,0.032356931,0.029230847,-0.005202324,-0.146375894,0.013446301,0.075869963,-0.044081592,-0.001648343,-0.00836555,0.073079411,0.022096595,0.036365099,-0.049628395,0.039223748,-0.138046246,-0.154705542,1.498467606,2.311117238,-1.463672002,-2.09456488,-1.555823067,-2.385668076,-0.591078323,-0.691225662,-1.303547332,-2.314396311 -4810,E277F,-0.017330264,-0.015818521,-0.001955407,-0.047509547,-0.970996006,0.023187961,0.04503544,-0.079695967,0.059023708,-0.06838168,0.036744639,-0.047610789,0.043699975,-0.108437927,0.013418834,-0.664691444,-1.277300568,1.354170643,1.640203979,-7.78295049,-7.131377991,-8.803028557,-8.818500336,-5.999906975,-8.161938591,-6.088351667,-4.501029945 -4811,E277I,0.02674516,0.052386546,0.082034817,-0.011727811,-0.01757013,0.027342504,0.083245793,-0.029755474,0.028970051,0.070982217,0.033790875,0.112211049,0.051858585,-0.033378472,0.00992285,0.048705822,-0.083846082,1.097952375,2.666035962,-7.15067252,-6.429479706,-8.461775719,-8.250545624,-5.630901375,-6.980660179,-5.850008074,-5.066813212 -4812,E277H,0.016540236,0.028481398,0.027761926,-0.013478224,-0.333711473,-0.014119486,0.058862456,-0.025781984,0.040991694,-0.023497628,0.080460423,0.001921925,0.053601927,-0.069117213,0.042160765,-0.25739284,-0.410030105,1.518693398,2.092570334,-5.512467914,-5.171307449,-6.516370743,-6.496917038,-4.239128746,-5.138615593,-4.387670697,-2.901834186 -4813,E277K,-0.002266838,0.055085321,0.001325197,-0.039372177,-0.144432723,0.006487571,0.047720422,-0.052254097,0.063334585,0.014966409,0.095204233,-0.030036887,0.032687281,-0.070155306,-0.008589047,-0.112944472,-0.175920973,1.492804858,2.390099507,-2.438361826,-2.092287849,-3.122086487,-3.958044182,-1.105299278,-1.914091331,-2.528163857,-0.907644096 -4814,E277M,-0.002316351,-0.019171449,0.011471608,-0.008560809,-0.253701899,-0.016115138,0.057490763,-0.062123465,0.06617192,-0.022979515,-0.015363382,0.003998208,0.018945008,-0.046405736,0.029284118,-0.216424903,-0.290978894,1.467410869,2.128036376,-6.61972942,-6.024707893,-7.951825562,-7.861085602,-5.205350021,-6.055678024,-5.511907997,-4.668250237 -4815,E277L,-0.005365258,0.030166009,0.0342485,-0.0046235,-0.074407516,0.005097566,0.041512404,-0.05224292,0.029298435,0.023745141,0.036586877,0.034587132,0.033909868,-0.050821065,0.041574066,-0.047742792,-0.10107224,1.318882223,2.493946148,-5.88575791,-5.366078186,-7.516418495,-7.241972374,-3.872319862,-5.432000633,-4.950276888,-3.215516136 -4816,E277N,-0.057248498,0.030892616,-0.008512259,-0.050059604,-0.077807463,0.017271898,0.015655127,-0.130152123,0.053122975,0.058609412,0.003175819,0.045469067,-0.062493585,-0.083196358,-0.016922849,-0.022119609,-0.133495317,1.276755325,2.520657352,-3.571744055,-3.095841568,-3.872782104,-4.402131607,-2.805825874,-3.682139122,-4.031186585,-2.30439738 -4817,E277Q,0.052980546,0.05491105,0.047420889,-0.015463111,-0.046492212,-0.005248393,0.120838869,-0.014877777,0.038516379,0.017216727,0.092605372,0.031468465,0.063373312,-0.042786448,0.011860226,-0.047231612,-0.045752811,1.2110845,2.347432485,-2.620001192,-1.780935944,-3.854248985,-3.691290825,-1.610403709,-2.163126495,-2.827270372,-0.867620832 -4818,E277P,-0.038016095,-0.01238717,-1.066721951,-2.016079391,-2.622383871,-0.005143306,0.034958381,-0.11099057,0.035336323,-0.014713672,-0.010060667,-0.843189774,-1.290254128,-1.989312446,-2.042846336,-2.389361708,-2.855406033,1.983872644,0.821750433,-7.379614151,-6.668447258,-8.614418144,-8.427169083,-6.205039818,-6.982996452,-6.796714986,-6.379811591 -4819,E277S,-0.001505463,0.024718659,0.026446672,-0.018985389,-0.123684104,0.011604761,0.047373388,-0.050384314,0.033215354,0.004082055,0.045355263,0.030914627,0.021978717,-0.054125813,0.016155035,-0.100494319,-0.146873888,1.416621327,2.308803801,-2.628682588,-2.102047646,-3.711332954,-3.686816696,-1.187179756,-2.456035889,-3.291112973,-1.465848947 -4820,E277R,0.015267132,0.019348055,0.026553127,-0.028979583,-0.086642792,0.015111665,0.066228191,-0.035693927,0.012924911,-0.021498694,0.060194803,0.019735393,0.033370861,-0.080208066,0.0222489,-0.106995988,-0.066289596,1.360625206,2.27497444,-2.943999084,-2.73182634,-4.697427536,-3.849660469,-1.646804756,-1.794276321,-2.733408077,-0.743203059 -4821,E277T,-0.001347203,0.026787441,0.035428137,-0.026144113,-0.100850902,0.029270477,0.050442532,-0.053136938,-0.007021241,-0.03967362,0.093248501,0.010674177,0.060182097,-0.102839091,0.050550866,-0.13447388,-0.067227924,1.384551697,2.18563951,-3.533844376,-3.272731133,-4.000649994,-4.580359436,-2.17082708,-3.644654236,-3.316163995,-1.885857704 -4822,E277W,-0.026001196,-0.007137312,-0.016372995,-0.044038305,-1.529771359,-0.006538233,0.017627132,-0.069629524,0.021208187,-0.050581665,0.036307041,-0.045208881,0.012462892,-0.085643733,-0.002432877,-1.311807809,-1.747734908,0.975727864,1.362554649,-8.852678394,-8.081930473,-10.37750714,-9.884582161,-7.319036278,-8.600335915,-7.47587962,-6.706750902 -4823,E277V,0.007497515,0.025001303,0.036874386,-0.025952249,-0.169901523,0.019783886,0.074956539,-0.05996151,0.028857715,-0.005515464,0.055518069,0.030579073,0.043169699,-0.082253906,0.030349408,-0.149402741,-0.190400304,1.544053338,2.281105729,-6.199258553,-5.73860424,-7.461063789,-6.930171829,-4.716852974,-6.14959993,-5.638574747,-4.352475737 -4824,E277Y,0.073440804,0.099287529,0.06351747,-0.007164806,-0.677625439,0.030940656,0.152797864,-0.005916257,0.052870798,0.045753694,0.152821363,0.029339566,0.097695374,-0.067293639,0.052964028,-0.515316505,-0.839934373,1.082772004,1.58018952,-8.321023488,-8.02440509,-9.050229919,-9.376322815,-6.453161781,-8.700997833,-6.661261153,-5.576851957 -4825,I278A,0.056076494,0.028877333,-0.905099745,-2.035603059,-2.41015192,-0.075667004,0.066785317,0.04536767,0.027280596,0.073148707,-0.015394041,-0.601011448,-1.209188042,-1.980647338,-2.090558779,-2.255627176,-2.564676663,1.377437673,0.673649424,-9.569987471,-9.122805,-8.532033669,-12.10747746,-8.440510849,-9.647110382,-5.048038636,-0.252753314 -4826,I278C,0.065918774,0.035751885,-0.059023067,-1.577073297,-2.724411475,-0.036649747,0.099327912,0.032509635,0.065721966,0.030089088,0.041414682,0.052336402,-0.170382535,-1.563238011,-1.590908582,-2.450037677,-2.998785273,0.585040879,0.693055455,-11.93246632,-10.99329163,-13.01908903,-14.849301,-11.38590974,-9.414740189,-7.404019873,-4.375159422 -4827,I278E,0.062813934,-1.417552949,-1.736848267,-2.11235497,-2.768557532,0.002203827,0.08518151,0.040446357,0.096017496,-1.311130323,-1.523975575,-1.767665047,-1.706031487,-1.919180678,-2.305529262,-2.629889085,-2.907225979,3.822299005,1.679839601,-14.74915459,-14.3839467,-15.16718099,-16.8797562,-13.77609933,-13.53878972,-9.977288552,-9.693275619 -4828,I278D,0.032391768,-1.845094753,-2.244240492,-2.150821148,-2.718978081,-0.003324025,0.072799848,-0.008016312,0.0183429,-2.177111928,-1.513077577,-2.156525397,-2.331955587,-2.308041028,-1.993601268,-2.541628181,-2.896327981,-0.704536803,-1.130024621,-15.01972886,-14.64855177,-15.67748311,-17.58568492,-13.66431274,-13.52261175,-9.977288552,-9.693275593 -4829,I278G,0.045045383,-1.397642504,-1.981529313,-2.168300621,-3.270264765,-0.025708788,0.079393975,0.010696791,0.065685841,-1.372030564,-1.423254443,-1.870688493,-2.092370132,-2.087144931,-2.24945631,-3.511063783,-3.029465746,-0.873349434,-1.111130082,-14.94687464,-14.55639507,-15.22080136,-17.83537323,-13.61082409,-13.51097946,-8.996816221,-6.773250018 -4830,I278F,0.075004417,-0.028025586,0.06614773,-1.197257717,-2.779089453,-0.086957604,0.107313311,0.042695523,-0.107637106,-0.067810848,0.011759677,0.022225618,0.110069842,-0.585527703,-1.808987731,-2.670373204,-2.887805702,0.813131357,0.847523415,-10.23249992,-9.626586319,-10.85892978,-11.46787797,-9.776989151,-9.432116402,-6.963039209,-4.431209841 -4831,I278H,0.022980293,-1.128870226,-1.750135979,-2.248181977,-2.801357298,-0.024986418,0.067765057,-0.021804472,0.069690439,-1.127485926,-1.130254525,-1.58402065,-1.916251308,-1.793528228,-2.702835726,-2.395092166,-3.20762243,3.836518748,1.907514691,-15.10958502,-13.90549351,-16.17165051,-17.87835545,-13.72857601,-13.86384961,-9.977288552,-9.693275573 -4832,I278K,0.028567112,-1.668862871,-1.806569238,-2.324074269,-2.392231202,0.028536968,0.065829579,-0.008695356,0.002722858,-1.411025189,-1.926700552,-1.867559913,-1.745578562,-2.019075544,-2.629072993,-2.252662697,-2.531799706,-0.309488493,-0.856612659,-14.0848083,-13.59405472,-14.71755333,-16.05938984,-12.58090678,-13.47213683,-9.977288552,-9.693275584 -4833,I278M,0.069461297,0.049382436,0.027597952,0.035536512,-0.522765186,-0.067497361,0.1080133,0.030909293,-0.095063632,0.069080919,0.029683952,0.003186965,0.052008938,0.010238248,0.060834776,-0.326693028,-0.718837344,1.040272799,1.684636361,-6.402777736,-6.337168297,-7.415621361,-7.194451614,-5.821820992,-5.244826416,-5.750535378,-3.092388428 -4834,I278L,0.02015708,-0.006131221,0.042032731,0.042220061,-0.61840592,-0.023898532,0.035174344,0.005139815,0.028627474,0.028711251,-0.040973692,0.066075192,0.017990269,0.045062612,0.03937751,-0.40022498,-0.836586859,0.848657977,1.542419891,-3.757869556,-3.94019812,-4.591186295,-4.456968964,-2.92995623,-2.87103817,-2.904536584,-1.260680654 -4835,I278N,-0.003691396,-1.383026415,-1.481142159,-2.450192183,-2.518349116,-0.095595067,0.002771456,-0.010154248,0.055595361,-1.501944838,-1.264107992,-1.356419571,-1.605864747,-2.109995193,-2.790389173,-2.343582346,-2.693115886,3.337052772,1.280878699,-14.32874286,-13.52383824,-15.44965825,-16.9105555,-13.2680683,-12.491594,-9.977288552,-9.693275553 -4836,I278Q,0.03504747,-0.938294285,-2.106349572,-2.198735763,-2.882117157,-0.080533878,0.052638228,0.017456711,0.124376379,-0.640734687,-1.235853883,-2.352541916,-1.860157228,-2.504057547,-1.893413979,-2.7376447,-3.026589613,0.334101503,-0.536750225,-14.0307673,-13.78402149,-14.70478193,-16.45904272,-12.11251338,-13.09347699,-9.977288552,-9.693275571 -4837,I278P,0.033718616,-1.418717578,-1.949484034,-2.354086114,-2.732630383,-0.02038558,0.060098527,0.007338705,0.038612642,-1.350296036,-1.487139119,-2.028679509,-1.870288559,-2.282857482,-2.425314746,-2.651143209,-2.814117556,0.128680822,-0.821789707,-14.86634902,-14.35851046,-15.09696471,-17.30838338,-13.78354916,-13.78433737,-9.977288552,-9.693275599 -4838,I278S,0.052937463,-0.88193843,-1.978042302,-1.819657229,-2.904324884,-0.045775202,0.084024376,0.021850549,0.067296853,-0.514962814,-1.248914045,-2.177423321,-1.778661282,-1.913965604,-1.725348854,-2.562526105,-3.246123663,0.628439515,-0.438363358,-11.86347583,-10.9033968,-12.76568087,-14.49189594,-10.86150108,-10.29490448,-6.579873508,-3.81254783 -4839,I278R,0.060562941,-1.534849795,-1.864500543,-2.115274629,-2.68954879,-0.033131503,0.083989321,0.037136561,0.024460083,-1.497266576,-1.572433013,-1.693389155,-2.035611931,-1.996172462,-2.234376796,-2.609970856,-2.769126724,3.648520262,1.399044997,-14.57268063,-14.40202109,-15.02070216,-16.8340152,-12.96193227,-13.64473245,-9.977288552,-9.693275551 -4840,I278T,-0.026246092,0.000783217,-0.397248313,-1.66426204,-2.232084643,-0.052512998,0.024446786,-0.07693897,0.062830223,0.078464543,-0.07689811,-0.066842835,-0.727653791,-1.676652863,-1.651871216,-2.252662697,-2.211506588,0.823540921,0.697971231,-7.864695319,-7.191811569,-7.531070328,-8.079557076,-8.162893578,-8.358144043,-4.445008803,-1.800922685 -4841,I278W,0.028259215,-0.058341937,-1.059824487,-1.756913837,-2.958656634,0.004918201,0.086440298,-0.029921868,0.017499161,-0.028113709,-0.088570164,-0.774270413,-1.34537856,-1.880028554,-1.63379912,-2.812585711,-3.104727557,2.015521914,0.882050157,-13.88598817,-13.4723839,-14.63556781,-15.63789467,-13.05714108,-12.6269534,-9.977288552,-9.693275597 -4842,I278V,0.051657168,0.033056886,0.050607289,0.014369836,-0.232038281,-0.01799932,0.061227442,0.042086893,0.086286767,0.058578774,0.007534997,0.053344214,0.047870364,0.044035663,-0.015295991,-0.174275784,-0.289800778,1.253981014,2.066721783,-3.526197812,-3.294229965,-2.49047261,-4.677462196,-3.258051437,-3.91077285,-4.557110041,-0.209129496 -4843,I278Y,0.049432917,-0.672297378,-1.949380546,-2.5064762,-2.574633133,0.042156168,0.131059685,-0.032193852,0.063598026,-0.325853579,-1.018741177,-1.58402065,-2.314740442,-2.036566276,-2.976386123,-2.270153429,-2.879112836,3.799390638,2.094074671,-13.12294019,-12.39918124,-14.34595773,-14.60875337,-12.29360677,-11.96720184,-8.970978559,-6.618413068 -4844,G279A,0.035083304,-0.032186025,-0.013159029,-0.003202019,-0.144679187,-0.069718238,0.0377407,0.032425907,-0.001010239,-0.037498793,-0.026873256,-0.018709422,-0.007608636,0.003637809,-0.010041847,-0.149199212,-0.140159162,1.452302797,2.274159377,-4.399134348,-4.91506012,-4.970529839,-4.785154892,-3.18550975,-4.139417137,-4.783181929,0.564551247 -4845,G279C,0.03151748,-0.026482436,0.013056864,0.033366771,-1.062366435,-0.126928682,0.046972721,0.016062239,-0.032333613,-0.007090698,-0.045874174,-0.03903644,0.065150167,0.076900598,-0.010167056,-0.9779717,-1.14676117,0.610259045,1.348010358,-11.84284135,-12.67624622,-12.39539081,-13.47169671,-10.15562521,-10.5152478,-9.15576674,-5.980533335 -4846,G279E,0.005416384,0.012067668,-0.878178737,-1.935768219,-2.340217753,-0.115251514,0.013305577,-0.002472809,0.058230636,-0.09380864,0.117943975,-0.476459473,-1.279898001,-1.736215541,-2.135320897,-2.058966791,-2.621468714,3.25636845,2.088183917,-12.38293445,-12.69776743,-12.45172106,-14.22418253,-11.17755183,-11.36344942,-10.58585342,-9.379787925 -4847,G279D,-0.029044134,-0.854573944,-2.063879468,-2.436225623,-2.457716759,-0.012036937,0.049457115,-0.107545383,-0.000569711,-0.47751612,-1.231631767,-1.969730828,-2.158028107,-1.883133922,-2.989317323,-2.586096414,-2.329337104,3.447923629,1.555061337,-11.7726964,-11.92055965,-12.26712797,-13.44915276,-10.60490658,-10.62173504,-9.673791891,-6.710562507 -4848,G279F,0.045047278,0.015083473,0.051430796,-0.716466737,-2.008497757,-0.18796916,0.035834656,0.0542599,-0.047112545,-0.031159643,0.061326588,-0.00450867,0.107370262,-0.481933241,-0.951000232,-1.827250319,-2.189745194,1.675264696,1.419853703,-13.09671808,-14.17227074,-13.78717834,-14.08385156,-11.71718905,-11.72310072,-9.610975058,-6.535952267 -4849,G279I,-0.010072222,-0.099754063,-0.051053203,-0.646870635,-1.940218459,-0.131474791,0.018001295,-0.038145738,0.050343407,-0.022823671,-0.176684455,0.010181583,-0.112287988,-0.236220713,-1.057520557,-1.650387666,-2.230049251,1.379284386,1.383938149,-13.88539047,-15.59617775,-13.68665834,-16.44673135,-11.69564648,-12.00173843,-9.079843102,-6.318015759 -4850,G279H,0.015607239,-0.025921147,-0.559668554,-1.859004136,-2.631557034,-0.076138964,0.028232437,0.00298204,-0.041414129,-0.056268092,0.004425799,-0.301029996,-0.818307111,-1.76075137,-1.957256902,-2.726955296,-2.536158772,1.424476183,0.757441801,-13.10324638,-13.57627797,-13.78960477,-14.06519797,-11.88680075,-12.19835043,-10.59389423,-9.402820286 -4851,G279K,-0.016716695,-0.620964551,-2.128942205,-2.390363985,-2.47432449,-0.089340656,0.100956735,-0.134390125,-0.032263424,-0.427168592,-0.814760509,-2.037482612,-2.220401797,-2.126976965,-2.653751005,-2.352818202,-2.595830777,1.209932476,-0.13442447,-13.06173776,-13.51913237,-13.06761275,-15.00838102,-11.62739579,-12.08616689,-10.59389423,-9.402820286 -4852,G279M,-0.048779506,-0.00516402,-0.006060875,-0.29554102,-1.713228001,-0.132425574,-0.004543443,-0.093015568,-0.013589511,0.023011035,-0.033339075,0.049626002,-0.061747752,-0.020124293,-0.570957746,-1.422056789,-2.004399212,0.453510151,1.312111566,-11.3868215,-12.84522128,-9.721073952,-14.39895261,-9.435954063,-10.53290557,-7.464215918,-4.481962003 -4853,G279L,0.023121024,-0.034256785,0.01195786,-0.590287792,-1.730182212,-0.16306207,-0.012345207,0.058587254,-0.030122669,-0.049674864,-0.018838705,-0.027921128,0.051836848,-0.361655503,-0.818920081,-1.668981941,-1.791382482,1.56996557,1.431436233,-14.18848948,-15.27959137,-13.71591731,-17.07220944,-12.41383508,-12.4608942,-10.52752701,-8.935342308 -4854,G279N,-0.0688805,0.007207674,-0.090671892,-1.404416954,-2.428784255,-0.000829236,0.057179403,-0.194940403,-0.075757726,-0.072694277,0.087109624,-0.112342484,-0.069001299,-1.303068224,-1.505765684,-2.130969453,-2.726599057,2.40748187,1.541304139,-11.74133575,-12.73100261,-11.60441441,-13.4548127,-10.8548148,-10.06163426,-9.611257592,-6.712529404 -4855,G279Q,-0.000674041,0.008410374,-0.329597648,-1.821198371,-2.624825223,-0.074202246,0.022672906,-0.024020988,-0.064353979,-0.04616423,0.062984978,-0.225622729,-0.433572567,-1.536175487,-2.106221255,-2.502379414,-2.747271031,1.339068178,0.774209275,-12.27831988,-12.74825313,-12.2106631,-14.43006277,-10.91652138,-11.08609903,-10.02683485,-7.364347617 -4856,G279P,0.015901239,-0.83331947,-1.94945741,-2.078344168,-2.798225476,-0.063610445,0.011869478,0.019933,0.026474935,-0.637747713,-1.028891226,-2.052586975,-1.846327844,-2.054931153,-2.101757182,-2.79928633,-2.797164621,1.443096457,-0.136702424,-12.68594377,-13.1744623,-12.68875695,-14.235978,-11.41814249,-11.91237912,-9.618949954,-6.709987607 -4857,G279S,0.003946601,-0.025150499,-0.016562023,0.016438826,-0.343477982,-0.066889618,-0.010367532,0.018260733,-0.020194877,-0.041025058,-0.00927594,-0.040134222,0.007010177,0.021495394,0.011382258,-0.289011818,-0.397944145,1.213425211,1.836332496,-5.621824272,-6.443435623,-6.837715508,-6.886850807,-4.425131218,-3.515988205,-5.562993167,-0.104864469 -4858,G279R,-0.033398583,-0.565416332,-1.889226946,-1.998709807,-2.726890745,-0.028573312,-0.018602143,-0.048195023,-0.007219631,-0.285756944,-0.84507572,-1.93142922,-1.847024671,-1.844832314,-2.152587299,-2.496642283,-2.957139207,1.095507857,-0.06830159,-12.08705377,-12.5523393,-12.35028331,-14.34890885,-10.25864632,-10.92509108,-9.373243636,-6.318015742 -4859,G279T,0.014495283,-0.024648527,-0.012319447,0.019491731,-1.678160555,-0.111023804,-0.008623725,0.03761429,-0.013559612,-0.022746456,-0.026550598,-0.025158877,0.000519983,0.065790336,-0.026806875,-1.663965332,-1.692355777,0.571192333,1.30799748,-8.105794716,-9.183267929,-7.00078318,-11.76880763,-6.218376122,-6.357738716,-6.148769525,-0.726459904 -4860,G279W,0.029707326,-0.024021488,-0.080267683,-1.537666186,-2.295020434,-0.188653843,0.034229827,0.025184824,0.006363301,-0.021740562,-0.026302413,0.003738381,-0.164273747,-1.330342309,-1.744990063,-2.459273533,-2.130767334,0.70397686,0.718568823,-13.79455441,-14.27525241,-14.38844505,-15.64309074,-12.16962045,-12.49636343,-10.59389423,-9.402820286 -4861,G279V,0.020557686,-0.004060423,-0.003508372,-0.456489365,-1.91550309,-0.187586318,0.029302545,0.011812826,-0.057438011,-0.021187125,0.01306628,-0.035848659,0.028831916,-0.218384964,-0.694593765,-1.848632252,-1.982373927,1.239326325,1.340229511,-10.80466221,-11.71678468,-11.21245773,-13.6775176,-8.154507042,-9.262043968,-6.701905239,-2.840194216 -4862,G279Y,-0.025694175,-0.007533052,-0.041436919,-1.39304885,-2.126980805,-0.249950124,-0.094223453,0.042835104,-0.012657035,-0.005692146,-0.009373958,-0.066395546,-0.016478291,-1.575609682,-1.210488017,-1.947578955,-2.306382654,3.137502062,2.144082874,-13.62306969,-14.00416248,-14.84832811,-14.59426494,-12.34747366,-12.32111926,-10.33023528,-7.961943686 -4863,A280C,-0.012123014,0.005180578,0.006360944,0.026847236,-0.422953844,-0.04859699,-0.050141592,0.025895565,0.0423568,0.016852827,-0.006491672,0.024187019,-0.011465132,0.038886318,0.014808153,-0.243557561,-0.602350126,1.132350998,1.834234278,-7.138248729,-6.551544769,-7.66185553,-7.636461403,-7.396858025,-6.444523918,-8.578425567,-8.166355106 -4864,A280E,-0.068131829,-0.010652531,-0.044225234,-0.023658128,0.017609574,-0.004638617,-0.077869781,-0.058393877,0.002337956,0.040451276,-0.061756338,-0.01731095,-0.071139517,0.019574082,-0.066890338,0.07909559,-0.043876443,1.075653676,2.805858865,-1.431726546,-0.897412155,-2.161764984,-1.325609276,-1.861209862,-0.912636452,-2.558286352,-0.310539899 -4865,A280D,-0.060825261,0.079135888,0.012624161,0.02748281,0.002623798,0.012943793,-0.02575471,-0.095895812,0.045115713,0.11376284,0.044508935,0.079243719,-0.053995398,0.127950798,-0.072985178,0.031826023,-0.026578427,1.054305364,2.766293118,-2.959758578,-3.163755356,-2.803217163,-3.156321953,-2.957325943,-2.718172478,-3.69589031,-2.748780747 -4866,A280G,-0.028084208,0.032488889,-0.009374351,-0.004871993,-0.030074453,-0.02445038,-0.067934506,0.011766091,0.006655707,0.057650043,0.007327735,-0.004435183,-0.014313519,-0.001137383,-0.008606602,-0.014858978,-0.045289927,1.361151851,2.636384469,-2.699690225,-2.382833427,-3.141731659,-2.086073944,-3.382511063,-2.505301033,-4.430067201,-1.824280479 -4867,A280F,-0.003369911,0.099714693,0.000668165,0.042391037,-0.02941169,0.016562666,-0.084948933,0.078209112,0.062382738,0.105636219,0.093793166,0.013668392,-0.012332063,0.039626173,0.0451559,-0.021671094,-0.037152285,1.284620528,2.631746913,-7.264147266,-6.339791618,-7.788956841,-8.125723488,-7.940070946,-6.126193436,-6.772227335,-3.779980548 -4868,A280I,-0.090391735,0.034865863,-0.080872316,0.006725181,-0.036654566,0.037384397,-0.102210428,-0.078573041,0.165819234,0.066449324,0.003282402,-0.052252757,-0.109491874,0.048984496,-0.035534135,-0.013861428,-0.059447704,1.222799075,2.609186557,-6.331086253,-5.841335213,-7.811389709,-5.750956497,-7.054577637,-5.197172211,-6.381855316,-4.438068099 -4869,A280H,-0.012493345,0.038923494,-0.032212808,0.015057306,-0.00561883,-0.078405741,-0.052569378,0.027582688,0.011639449,0.075946988,0.0019,-0.00655758,-0.057868036,0.065331573,-0.035216961,0.048224166,-0.059461825,1.211130532,2.938980839,-3.784533521,-3.212915939,-4.17752282,-4.200681366,-4.24639418,-3.085153297,-4.418092198,-2.193472331 -4870,A280K,-0.020814739,0.04003729,0.070316406,0.017820957,0.075160398,0.118836564,-0.017571261,-0.024058216,0.194957088,0.043708359,0.036366221,0.137425235,0.003207577,0.072859906,-0.037217992,0.05945985,0.090860946,1.238730648,3.03239212,-1.184081187,-0.611637024,-1.896820274,-2.051867912,-1.036351318,-0.323729408,-1.871969105,0.689393378 -4871,A280M,-0.009311223,0.039352789,-0.020111633,0.053095138,0.037007801,-0.001755541,-0.055072618,0.036450172,0.160396349,0.040981227,0.03772435,0.012478395,-0.052701661,0.064932038,0.041258238,0.100912533,-0.026896931,1.136552211,2.979708831,-6.49145141,-5.281763527,-7.348269585,-6.782271965,-7.379421593,-5.66553038,-6.564189695,-4.463718895 -4872,A280L,-0.019694195,0.025673355,-0.01540002,0.007323597,-0.032356586,-0.057590987,-0.072462931,0.033074541,-0.041337933,0.039685653,0.011661056,0.004835358,-0.035635398,0.002207067,0.012440126,0.006857073,-0.071570244,1.211678106,2.635594997,-4.813150089,-4.032753578,-5.564761322,-4.840736778,-5.864356049,-3.763142715,-5.606936851,-1.740101129 -4873,A280N,-0.100248609,-0.018032502,-0.058417893,-0.017596726,0.011650471,0.051055959,-0.145688258,-0.054808959,0.173896735,0.033277353,-0.069342357,-0.008394362,-0.108441423,0.001750831,-0.036944283,0.03792009,-0.014619149,1.010840145,2.617139047,-3.237784247,-3.241913925,-3.439167419,-3.859698219,-3.247622047,-2.400519623,-4.048414061,-2.579443896 -4874,A280Q,0.027686207,0.025232728,-0.048104238,-0.025300794,0.001830592,-0.096644102,-0.016242965,0.071615379,0.015339323,-0.022432943,0.072898398,-0.102096837,0.005888362,-0.037828254,-0.012773334,-0.01482549,0.018486674,1.253057574,2.527943263,-2.338502061,-1.304825294,-2.531812386,-2.752311676,-3.691079041,-1.412481911,-4.094976136,-1.072879466 -4875,A280P,-0.052883669,-0.25733373,-1.638715274,-2.026569518,-2.494082504,-0.00500672,-0.053874835,-0.051892502,-0.01778646,-0.024267108,-0.490400352,-1.546081799,-1.731348749,-2.017006479,-2.036132557,-2.489746225,-2.498418782,0.68246934,0.032625318,-6.340728438,-5.618385521,-6.792258232,-6.468906944,-6.906109055,-5.917982437,-7.183336431,-5.852633053 -4876,A280S,-0.103758607,0.036970363,-0.000966615,0.011164307,-0.015325554,-0.019862738,-0.154398868,-0.053118346,0.024947888,0.058761016,0.015179709,0.022746319,-0.024679548,0.035314076,-0.012985462,0.045050127,-0.075701234,1.067914636,2.733284345,-1.465866992,-1.090643898,-1.631773102,-2.087677582,-1.56996637,-0.94927401,-3.188115681,-0.958801899 -4877,A280R,0.017740767,0.05951084,0.006637577,0.031565471,0.030679469,-0.035991029,-0.010064205,0.045545738,0.007392147,0.067349827,0.051671853,0.033894026,-0.020618873,0.032269788,0.030861154,0.058416162,0.002942776,1.095273149,2.786239634,-1.063803473,-0.16541465,-2.024160873,-0.934769829,-1.862074379,-0.332597633,-2.244745634,1.42050813 -4878,A280T,-0.048665015,0.063407862,0.026680456,0.006376666,-0.043402807,-0.058561346,-0.088006379,-0.009323651,0.019177593,0.100990257,0.025825466,0.077937537,-0.024576625,0.036448562,-0.02369523,0.006806875,-0.093612489,1.187963924,2.700960641,-2.185598773,-1.739236038,-3.233392426,-2.007458435,-1.444947906,-2.502959061,-4.939772733,-1.59533492 -4879,A280W,-0.038685722,0.078896382,0.036756765,0.038898169,-0.063529329,-0.025649927,-0.098913037,0.021541593,-0.005865896,0.114410144,0.04338262,0.057997495,0.015516034,0.088844195,-0.011047857,-0.015685587,-0.111373071,1.320991183,2.688033352,-7.252454016,-6.233908028,-7.758049736,-7.44266568,-8.285116524,-6.542530113,-6.966581261,-4.720765437 -4880,A280V,-0.057265898,0.043899446,-0.000779529,0.018186573,0.001853805,-0.037710621,-0.055955917,-0.058575878,0.015356202,0.063123972,0.02467492,0.029402109,-0.030961166,0.029258505,0.007114641,0.01941985,-0.015712241,1.192823506,2.797653427,-4.861397794,-4.380884155,-5.938834618,-4.366484299,-5.466163773,-4.154622124,-5.364610357,-3.554281568 -4881,A280Y,-0.009454823,-0.029276731,0.007612952,0.005662317,-0.060442832,-0.027633511,-0.075527353,0.056617707,0.084827758,-0.030583528,-0.027969934,-0.021769448,0.036995351,0.006669867,0.004654767,-0.035173565,-0.085712099,1.231813699,2.464042643,-6.434412991,-5.711936287,-6.985424469,-7.251418655,-6.69424234,-5.529043205,-6.376621215,-3.226069239 -4882,S281A,0.01085553,-0.015615372,0.007514437,-0.039074234,0.016871306,0.010089789,-0.002499243,0.024210303,-0.016133236,0.002812361,-0.034043104,0.023667263,-0.00863839,-0.019060533,-0.059087935,-0.021681544,0.055424156,1.217323422,2.511087281,0.14427984,-0.276025124,0.283797142,0.457348663,-0.217791451,0.474069969,-1.603115886,2.38968392 -4883,S281C,0.053243195,-0.048376631,0.025057258,-0.001752361,-0.239623183,0.106221029,0.069766883,0.036719507,-0.001240994,0.036123201,-0.132876462,0.096226065,-0.04611155,0.078779399,-0.082284121,-0.094814368,-0.384431997,1.297311562,2.346617768,-5.707864627,-6.809401367,-6.401614891,-4.579835785,-5.777933029,-4.970538063,-5.787106693,-2.106891927 -4884,S281E,-0.007462842,-0.033342317,-0.043318389,-0.023829752,0.019996552,-0.040562389,-0.017109755,0.002184072,0.034342079,0.009265406,-0.075950039,-0.002017359,-0.084619418,-0.039557422,-0.008102082,0.004274437,0.035718666,1.297628574,2.681264827,-2.809374051,-3.967486343,-2.861523804,-2.701222801,-3.045570419,-1.471066887,-3.321301437,0.440367555 -4885,S281D,-0.077237476,0.002967593,0.040606798,-0.042394062,-0.313969132,0.002262854,-0.113210404,-0.041264547,0.014181001,0.031783352,-0.025848166,0.112432165,-0.031218569,0.07422113,-0.159009254,-0.16092539,-0.467012874,1.285107436,2.126986297,-6.070603934,-7.370316093,-6.429463516,-4.561423157,-5.710173973,-6.281642929,-5.305890456,-1.616145361 -4886,S281G,0.005881285,-0.002000622,0.019861891,-0.010184149,-0.975169465,-0.020873779,-0.003243367,0.015005937,0.012599661,-0.007525282,0.003524039,0.006250759,0.033473022,-0.008162828,-0.012205469,-0.627710791,-1.322628139,0.903425576,1.460877675,-5.111068877,-5.824794464,-4.640191231,-4.148793312,-5.159087387,-5.782477989,-5.097862031,-1.862763575 -4887,S281F,0.005835314,-0.030240181,0.03461422,-0.02603058,-0.310771785,-0.016534306,0.042427538,-0.03075691,-0.117821473,-0.063410001,0.00292964,0.056097074,0.013131366,-0.082092214,0.030031054,-0.228832856,-0.392710714,1.40879113,2.056308501,-6.816553835,-9.1019636,-7.646335411,-4.393347389,-6.827552147,-6.113570625,-4.957149329,-1.670313408 -4888,S281I,0.016365684,-0.036928014,0.084866928,0.013927195,0.005375411,0.039656366,0.04474883,-0.012017463,-0.132619057,-0.03697463,-0.036881398,0.087358428,0.082375427,0.030403221,-0.002548832,0.032532574,-0.021781752,1.104549657,2.74042157,-3.612903059,-5.633551964,-3.598649063,-1.71165712,-3.376043503,-3.744613647,-3.20696145,1.871892489 -4889,S281H,0.054028882,-0.018238115,-0.004022538,-0.025059518,-0.001936764,-0.03088645,0.103399745,0.004658019,-0.017932383,0.005001527,-0.041477756,-0.015201859,0.007156783,-0.024961696,-0.025157339,-0.02463699,0.020763462,1.117285712,2.33927119,-5.241298933,-7.120121147,-6.220229385,-3.795232613,-5.071045288,-3.999866234,-4.513869297,-0.754445797 -4890,S281K,0.102200117,0.082772843,0.056158443,0.010449293,0.039123014,0.05533324,0.130421793,0.073978441,0.007471789,0.056828697,0.108716988,-0.031791173,0.144108058,0.08435519,-0.063456605,0.072993724,0.005252303,1.073481308,2.84020224,-5.215079967,-6.733151085,-5.168685638,-4.383788292,-4.709787872,-5.079986946,-4.965727952,-0.807621276 -4891,S281M,0.046340324,0.002224116,0.047706904,-0.004864593,-0.060161433,-0.128979141,-0.024259905,0.116940552,-0.104540839,-0.093797547,0.098245779,0.015665204,0.079748604,0.03809005,-0.047819236,-0.04566276,-0.074660106,1.334238511,2.487937686,-4.2298728,-4.375156494,-3.083568878,-2.550840004,-4.812668228,-6.327130394,-4.290896452,0.515005333 -4892,S281L,0.065905107,-0.011631881,0.001830731,-0.018031974,-0.086506977,-0.091464956,0.062313446,0.069496768,0.004320266,-0.010883369,-0.012380392,-0.067961653,0.071623115,-0.053169311,0.017105364,-0.135842591,-0.037171362,1.442559124,2.277564226,-3.177297583,-4.062046188,-3.341900551,-1.965266312,-3.205964935,-3.311309929,-2.280737296,2.077289625 -4893,S281N,0.040756012,-0.002860834,0.122798357,0.084669098,0.131987915,-0.107879686,0.068735407,0.012776616,0.030787635,-0.03542713,0.029705463,0.200397941,0.045198772,0.127648467,0.041689728,0.132208125,0.131767704,1.671448915,3.643209181,-6.011227293,-7.464455002,-6.939250214,-4.728059029,-5.824749344,-5.099622879,-6.295904548,-2.379626388 -4894,S281Q,0.055194085,0.005230144,0.042824474,0.036296139,0.020266376,0.065916681,0.059088891,0.051299279,-0.015463793,0.010167368,0.000292919,0.081910575,0.003738372,0.028228482,0.044363795,-0.018068113,0.058600865,1.232489823,2.596282822,-4.197163287,-5.045309669,-5.003689911,-3.342460945,-4.060533295,-3.533822617,-3.516328582,-0.419651928 -4895,S281P,-0.027270933,-0.031339725,0.007437963,-1.335726389,-2.321086677,-0.026976294,-0.016570323,-0.037971542,-0.016017306,-0.015280152,-0.047399297,-0.0000495,0.014925426,-0.775924246,-1.895528531,-2.148886691,-2.493286663,1.76810787,1.345903506,-7.948367554,-8.867920776,-8.178661491,-6.755058891,-8.11775206,-7.82244455,-8.34258018,-6.633886492 -4896,S281R,0.005082779,-0.012305844,0.021350131,-0.020843979,-0.042061968,-0.02472358,-0.007199574,0.017365132,0.000983058,-0.015506032,-0.009105655,0.010623277,0.032076984,-0.022133863,-0.019554095,-0.055785454,-0.028338481,1.271390899,2.402791355,-4.476138364,-5.889950378,-5.344072716,-3.27811203,-3.923041885,-3.945514809,-3.07421391,0.002672966 -4897,S281T,-0.021101201,-0.05234161,-0.058022299,-0.044012017,-0.000301299,-0.017484335,-0.005929792,-0.036272609,-0.014260803,-0.033776093,-0.070907127,-0.015541949,-0.100502648,0.01182373,-0.099847763,-0.025598469,0.024995871,1.138825853,2.478525199,-1.161035834,-1.713270538,-0.942879318,-0.583026443,-1.587745583,-0.978257286,-2.120028994,0.912376145 -4898,S281W,0.066108475,-0.01622506,-0.000134965,-0.018015178,-1.05525514,-0.003238927,0.080650176,0.051566773,-0.030642188,-0.05579145,0.02334133,-0.005308618,0.005038688,-0.054012978,0.017982623,-0.818980568,-1.291529712,0.660661684,1.371834235,-6.874536789,-8.565600319,-8.089257378,-4.244333984,-6.638842056,-6.834650208,-4.720291604,-1.64615239 -4899,S281V,0.047241332,-0.021570434,0.001705484,-0.03619773,0.013298684,0.001875731,0.06246056,0.032022103,0.03893919,-0.037257282,-0.005883585,0.002465779,0.000945189,-0.024586528,-0.047808932,-0.02855442,0.055151787,1.40029765,2.593260959,-2.687188548,-3.076527054,-3.282566368,-1.527530739,-2.800834068,-2.748484512,-2.253096128,1.501451567 -4900,S281Y,0.03572399,-0.005337117,0.095991598,0.079988106,-0.098156934,0.067030042,0.012192796,0.059255184,0.049781676,-0.050046039,0.039371805,0.084652535,0.10733066,0.127903709,0.032072502,-0.095550959,-0.100762908,1.298172133,2.38351553,-6.813423964,-9.667953979,-7.931272835,-4.094969162,-6.561759338,-5.811164505,-4.944999657,-0.782206306 -4901,L282A,-0.006364223,-0.014422667,0.038811576,0.040555563,-0.103001042,-0.05789565,-0.015008345,0.002279899,0.008801646,0.0060313,-0.034876633,0.028267529,0.049355623,0.021281102,0.059830023,-0.094163324,-0.11183876,1.228007054,2.330854478,-6.959006015,-6.847854607,-6.365532257,-6.585756821,-9.919909431,-5.075976959,-1.736767013,0.475156163 -4902,L282C,0.024221858,-0.025837514,0.029999443,0.027600953,-0.617685383,-0.048342535,0.067686109,-0.019242394,-0.024250696,-0.085879719,0.034204691,0.020650011,0.039348874,-0.026634519,0.081836424,-0.301801852,-0.933568914,1.591156184,2.123610937,-9.350562146,-8.254893822,-8.907105377,-9.647688782,-11.06213683,-8.880985916,-5.606901799,-3.00582367 -4903,L282E,-0.089289604,-0.028858181,-0.006049179,-1.210741376,-2.95431837,0.023525259,-0.053888225,-0.124690983,-0.033275574,-0.020251298,-0.037465064,0.031192466,-0.043290823,-0.909849571,-1.511633181,-2.783442611,-3.125194129,0.510439872,0.734900087,-13.18431576,-13.10236191,-11.90380754,-13.29089147,-15.03427296,-12.59024492,-8.428003155,-8.955041227 -4904,L282D,0.095681055,-0.490128511,-1.612933182,-1.888378306,-2.529507892,-0.029363658,0.120466996,0.070895114,-0.010494479,-0.210853365,-0.769403657,-1.643502025,-1.582364339,-1.971275849,-1.805480762,-2.438328709,-2.620687074,1.314422415,0.065799607,-13.63465051,-13.40165312,-12.88160228,-13.7447523,-14.71708669,-13.42815817,-8.428003155,-8.955041222 -4905,L282G,-0.008902769,-0.006361363,0.046912974,-1.146896856,-2.415650406,-0.023271938,0.028700842,-0.046506379,-0.027799141,-0.010859151,-0.001863574,0.014371325,0.079454622,-0.681482848,-1.612310864,-2.106418595,-2.724882217,1.699155243,1.344656418,-13.19512981,-12.99191829,-12.10270261,-13.56666977,-15.39203446,-11.92232394,-7.171341522,-5.954071214 -4906,L282F,-0.055590161,0.005981911,0.057414232,0.004002467,-0.663794413,-0.130479841,-0.054541186,-0.056639135,-0.018528412,0.01289498,-0.000931159,0.013658647,0.101169817,-0.092011034,0.100015968,-0.404161934,-0.923426892,1.575686152,1.971424326,-6.763994745,-6.537991333,-5.160462135,-7.389497696,-8.251776886,-6.480245674,-4.911864498,-3.113637934 -4907,L282I,-0.030712997,-0.085603368,0.073240526,0.014857092,0.07867216,0.036917857,-0.030478515,-0.030947479,0.024621081,-0.101026579,-0.070180156,0.058977284,0.087503768,-0.041905127,0.07161931,0.021191795,0.136152524,1.173520855,2.612980945,-0.985986638,-0.738607407,-1.457445915,-1.555861923,-1.333970917,0.155952972,-1.698817496,0.121882705 -4908,L282H,-0.079556787,-0.068685428,-0.665358415,-1.952067363,-3.011268548,-0.00296692,-0.048420416,-0.110693158,-0.029361256,-0.054606175,-0.08276468,-0.340755448,-0.989961382,-1.782472624,-2.121662102,-2.851585476,-3.170951619,1.501122905,0.762066714,-13.62198905,-12.73985181,-12.24635916,-15.09889507,-14.53711644,-13.48772279,-8.428003155,-8.955041222 -4909,L282K,-0.126796857,0.004379624,-0.801463799,-2.080419094,-2.571033681,0.049597325,-0.080987092,-0.172606621,0.049259315,0.04326869,-0.034509442,-0.383430637,-1.21949696,-2.225309282,-1.935528905,-2.391332146,-2.750735216,1.474676645,0.655737633,-12.59331108,-12.7056953,-11.95226952,-12.99592255,-12.95067691,-12.36199111,-8.428003155,-8.955041235 -4910,L282M,-0.011839937,-0.016202038,0.129120078,0.050533957,0.01266562,-0.032253916,-0.011335874,-0.012344,-0.00109089,-0.006299305,-0.026104771,0.138454299,0.119785856,0.025305865,0.075762048,-0.01373452,0.03906576,1.257108315,2.684097378,-1.763789801,-2.429444473,-2.68372496,-1.717015556,-1.619271225,-0.36949279,-2.542521292,-2.317121243 -4911,L282N,-0.078977727,-0.04154513,0.019547974,-1.903827248,-2.321377818,0.032683298,-0.007880062,-0.150075392,-0.086719893,-0.021768745,-0.061321515,0.014509371,0.024586576,-1.459392488,-2.348262007,-2.023355361,-2.619400274,1.09625668,0.750717847,-13.16298647,-13.08984703,-11.10187752,-14.15800237,-13.84783105,-13.61737439,-8.428003155,-8.955041242 -4912,L282Q,-0.084061408,-0.02514229,0.03698005,-0.013831643,-1.722284209,-0.03406479,-0.069408463,-0.098714352,-0.044841389,0.007363813,-0.057648393,0.054368744,0.019591356,0.031708728,-0.059372013,-1.623803868,-1.82076455,0.624152881,1.311173159,-11.75916212,-12.45222457,-11.13783887,-11.96074274,-11.8455355,-11.3994689,-8.048662405,-7.247377753 -4913,L282P,-0.041060384,-0.825747381,-1.903780429,-2.180446576,-2.427915802,-0.010656915,-0.009637888,-0.07248288,0.041194232,-0.600903414,-1.050591348,-2.028956322,-1.778604536,-2.228943566,-2.131949585,-2.263687516,-2.592144088,1.368162314,-0.144691753,-13.08374705,-13.0562671,-12.13835667,-13.41531433,-14.69991937,-12.10887778,-8.422041588,-8.92849771 -4914,L282S,-0.011399953,-0.030331722,0.066856979,0.016709489,-1.65506219,-0.037299618,0.020116828,-0.042916733,-0.04014848,-0.013204324,-0.047459119,0.047250607,0.086463351,0.066552627,-0.03313365,-1.473192433,-1.836931946,0.581981385,1.315810913,-11.03507537,-10.89045743,-8.511405144,-11.98425767,-12.29861272,-11.49064389,-5.557301726,-3.356527474 -4915,L282R,-0.052282905,-0.503940882,-1.761141165,-2.017129684,-2.703589801,0.001120214,-0.029214307,-0.075351503,-0.014434746,-0.232654089,-0.775227674,-1.825003591,-1.697278739,-2.022443646,-2.011815721,-2.415710292,-2.99146931,1.109877607,-0.02789721,-12.78764478,-12.97090181,-12.07993506,-12.88355535,-13.55982487,-12.44400683,-8.428003155,-8.955041242 -4916,L282T,-0.03096509,-0.027274398,-0.012731964,0.024637596,-0.231657908,0.039189424,-0.005562998,-0.056367181,0.030266844,-0.053668356,-0.00088044,-0.040834917,0.015370989,-0.016680716,0.065955907,-0.273546517,-0.189769299,1.458214821,2.055663362,-7.676662445,-7.786269516,-5.872508904,-8.73371151,-9.227489861,-6.763332436,-4.402049908,-1.406968372 -4917,L282W,-0.059803572,-0.096267983,-1.344352846,-1.780907616,-2.781623897,-0.023238423,-0.036687557,-0.082919586,-0.049234397,-0.036756795,-0.155779171,-0.887070025,-1.801635666,-1.955206538,-1.606608694,-2.723289393,-2.8399584,2.097516532,0.875908585,-11.63428513,-11.64499702,-10.64677985,-11.54240542,-12.60990466,-11.72733871,-8.428003155,-8.955041236 -4918,L282V,-0.033539782,-0.060183293,0.040918414,-0.014758485,-0.020573364,-0.00988052,-0.009174917,-0.057904647,-0.017338214,-0.036731061,-0.083635525,0.03151187,0.050324958,-0.038682434,0.009165464,-0.014466388,-0.026680339,1.265485044,2.416220875,-2.486444519,-2.276941559,-1.784178917,-2.882027328,-4.020611404,-1.468463387,-1.672163679,0.864363871 -4919,L282Y,-0.098260433,-0.082840786,-0.332795127,-1.633467035,-2.60798928,-0.079502726,-0.082745814,-0.113775051,-0.102314702,-0.086097144,-0.079584428,-0.086591695,-0.578998558,-1.58069694,-1.686237129,-2.445689808,-2.770288752,0.926737575,0.714213165,-12.12871137,-11.5340106,-11.29373071,-12.56489552,-12.89013869,-12.36078133,-8.428003155,-8.95504123 -4920,I283A,0.031470879,0.049791319,0.037768479,0.06238399,-0.537631351,-0.000624303,0.038498753,0.024443004,0.032871686,-0.09715811,0.196740747,0.018623557,0.0569134,0.031880449,0.09288753,-0.442120767,-0.633141934,0.633006162,1.441665311,-4.14370215,-6.564234894,-3.092006439,-1.638683884,-4.629826355,-4.793759178,-3.338428683,1.183837691 -4921,I283C,0.121179051,0.107003363,0.086868051,0.142311386,-0.657012279,-0.027048822,0.154521438,0.087836664,0.047843913,-0.05257339,0.266580116,0.045003413,0.128732688,0.088204515,0.196418257,-0.486427507,-0.827597051,0.614914715,1.421654264,-8.167929884,-10.48410428,-8.024063385,-6.232017303,-8.061752335,-8.03771212,-5.196253727,-2.259998438 -4922,I283E,0.051217483,0.076399452,0.03256536,-1.035371851,-2.601698129,-0.0003755,0.100605633,0.001829333,-0.031887886,-0.063245147,0.216044051,0.016283475,0.048847244,-0.538031649,-1.532712052,-2.725471013,-2.477925245,0.771546738,0.845372877,-12.03870164,-14.19002785,-10.02544182,-10.71721786,-12.17702981,-13.08379086,-9.066486241,-7.600373241 -4923,I283D,0.075010206,-0.255157678,-1.67594081,-1.915902265,-2.788857489,-0.064807294,0.127006231,0.023014181,-0.007570611,-0.151328788,-0.358986567,-1.167550513,-2.184331106,-1.975068838,-1.856735692,-2.637463395,-2.940251583,2.479119878,1.040888058,-12.98328707,-15.05801871,-11.7931121,-11.7786171,-13.04835824,-13.23832921,-9.066486241,-7.600373241 -4924,I283G,0.00841945,0.063248639,0.050212601,-1.074840201,-2.247811139,-0.027790242,0.046688957,-0.029850058,0.012110809,-0.073147911,0.199645188,0.041749982,0.058675219,-0.553903814,-1.595776587,-2.397469156,-2.098153122,1.5413125,1.263939184,-10.32637661,-12.43875707,-9.753404114,-8.528417503,-10.35202051,-10.55928384,-6.705257962,-4.368903826 -4925,I283F,-0.0587183,0.022810063,0.057892668,0.068766402,-0.123745791,0.03113466,0.010064407,-0.127501007,0.015709742,-0.113849663,0.159469788,0.11898656,-0.003201224,0.177611434,-0.040078631,-0.124861088,-0.122630494,1.226098114,2.254828956,-2.263350375,-2.091758324,-3.897251312,-2.358975319,-2.041904213,-0.926862709,-2.523712533,0.427777541 -4926,I283H,0.003075116,0.088448793,0.080689247,0.086491254,-2.078123175,0.018155201,-0.010737295,0.016887527,-0.009880693,-0.040085156,0.216982741,0.059959962,0.101418532,0.084568454,0.088414054,-1.74239138,-2.413854969,0.593308359,1.306097648,-11.03807585,-15.91757889,-9.080909927,-8.474869438,-10.66354205,-11.05347896,-6.16566191,-1.454240165 -4927,I283K,-0.033363263,0.090361426,0.033530172,-0.318691604,-2.249930577,0.005545774,0.022117594,-0.088844119,0.026230291,-0.033819149,0.214542,0.114736719,-0.047676375,0.05473879,-0.692121998,-1.846537857,-2.653323296,0.709068722,1.304894298,-12.36120688,-14.21554958,-10.1972829,-10.70731776,-12.19367207,-14.49221211,-9.066486241,-7.600373241 -4928,I283M,0.045112033,0.09082645,0.073791025,0.064655477,-0.088552239,-0.081727853,0.081430124,0.008793942,0.000315415,-0.030034094,0.211686994,0.064098947,0.083483103,0.013542573,0.115768381,-0.157879617,-0.01922486,1.070833104,1.919357515,-4.004889311,-4.008004608,-4.000053047,-4.461229431,-3.788598557,-3.766560913,-4.217919614,-1.342122456 -4929,I283L,0.059370475,0.055494218,0.060994301,0.063921914,-0.190349095,-0.051707738,0.066468173,0.052272776,0.010576258,-0.118033435,0.22902187,0.027483838,0.094504763,0.012760959,0.115082869,-0.234695529,-0.146002661,1.556426246,2.224228215,-4.005741454,-4.802651421,-4.2861185,-3.877147926,-3.141469505,-3.921319916,-3.709500744,-0.067305242 -4930,I283N,-0.030648929,-0.029058431,-0.09197065,-1.530969957,-2.485288831,0.034436635,0.011603071,-0.072900928,-0.013120868,-0.233481273,0.175364411,-0.00994266,-0.17399864,-1.090462256,-1.971477658,-2.354916805,-2.615660856,2.013138297,1.306079846,-11.9200045,-14.64477127,-11.35741799,-10.06872898,-11.85558034,-11.6735239,-8.13912334,-5.026295703 -4931,I283Q,0.018505338,-0.019192579,0.04345886,0.033764477,-1.955217642,-0.073513621,0.026432423,0.010578253,0.012311433,-0.175617759,0.137232601,-0.030118163,0.117035883,0.011300259,0.056228695,-2.049034307,-1.861400976,1.015707149,1.30464146,-12.30227622,-13.61869175,-10.62490625,-11.61660606,-12.22255326,-13.42862379,-8.414966215,-5.823655372 -4932,I283P,0.031016147,0.056008005,-0.731239346,-1.76919245,-2.613881608,-0.025240967,0.067333854,-0.005301561,0.039669411,-0.08784305,0.19985906,-0.337616518,-1.124862174,-1.706333613,-1.832051287,-2.502621749,-2.725141466,1.505870292,0.78508746,-12.14147141,-14.02287171,-11.11407906,-10.76376951,-12.20034685,-12.6062899,-9.066486241,-7.600373241 -4933,I283S,0.070348948,0.105294123,0.100497163,0.100852868,-1.487969518,-0.026790523,0.099579003,0.041118893,-0.007444504,-0.030907016,0.241495262,0.087790165,0.113204161,0.101033506,0.10067223,-1.260331056,-1.71560798,0.667836286,1.332935139,-7.259293163,-9.757903069,-7.19049762,-5.658660698,-7.298424904,-6.390979523,-5.004686594,-2.261343798 -4934,I283R,0.025069288,0.075470984,0.066976878,0.071882627,-1.948248642,-0.002438317,0.052025095,-0.001886519,0.027048027,-0.068010175,0.218952142,0.047321063,0.086632692,0.119725953,0.024039301,-1.69943643,-2.197060853,0.569567267,1.30601774,-12.39829141,-12.80030426,-10.64962248,-11.28397385,-12.31113908,-14.94641736,-6.271800121,-1.858296571 -4935,I283T,0.053066206,0.068222914,0.040272361,0.035321798,-0.300995366,0.015663807,0.098022774,0.008109638,0.034167308,-0.081143822,0.217589649,0.050691168,0.029853554,0.039052861,0.031590734,-0.311787741,-0.29020299,0.733911523,1.539474927,-6.568960875,-7.684437492,-5.048252525,-5.292153702,-7.796407509,-7.023553146,-4.56979412,-1.1242438 -4936,I283W,0.01963929,0.035328206,0.030233693,0.059807256,-1.71314797,-0.00078643,0.03358698,0.0056916,-0.003016056,-0.095860123,0.166516535,0.029254767,0.031212618,0.049099363,0.070515148,-1.186929665,-2.239366275,0.585629736,1.330068682,-9.626558827,-9.749376373,-10.88805367,-7.947074173,-8.848055344,-10.70023458,-5.398169186,0.54274985 -4937,I283V,0.071986976,0.068715027,0.084233081,0.056110357,-0.030749035,0.020343736,0.084107077,0.059866874,0.014520177,-0.058106626,0.195536679,0.054984194,0.113481968,0.062635996,0.049584718,-0.132006118,0.070508048,1.382819574,2.332674662,-1.719222194,-1.481829498,-1.489164352,-1.661772316,-2.323498833,-1.63984597,-2.017680151,1.307049636 -4938,I283Y,-0.019137919,0.023169872,0.023007479,0.067292346,-0.082166485,0.031967846,-0.058736069,0.020460232,0.158117888,-0.102568653,0.148908397,0.035997653,0.010017305,0.085629003,0.048955688,-0.063127466,-0.101205504,1.313105599,2.474889621,-6.397742931,-8.882764267,-7.280711273,-6.313466461,-4.687724472,-4.82404818,-4.951559262,1.652259243 -4939,K284A,-0.001167093,-0.0194963,0.011285005,0.006379218,-0.038962119,0.052943048,-0.032402192,0.030068006,-0.014523295,-0.032338695,-0.006653905,0.035927039,-0.013357029,0.004329126,0.008429309,-0.018958354,-0.058965884,1.671448915,3.643209181,,,,,,,, -4940,K284C,-0.030232924,-0.007676652,-0.000796423,-0.032056912,-0.918670018,0.053184482,-0.026563658,-0.03390219,0.026977849,-0.009735616,-0.005617687,0.024915488,-0.026508334,-0.043491694,-0.02062213,-0.554367288,-1.282972748,1.184962493,1.613005555,,,,,,,, -4941,K284E,-0.003045591,0.003268006,-0.0137895,0.007263862,-0.027480766,0.051614351,-0.036752754,0.030661572,0.006596286,-0.025887765,0.032423777,-0.00867321,-0.018905789,0.035238213,-0.020710489,-0.035196934,-0.019764597,1.356831749,2.646566522,,,,,,,, -4942,K284D,0.001921604,-0.019355702,-0.009024555,0.023140319,-0.061476142,0.027800756,-0.046579673,0.050422881,0.003573463,-0.001629866,-0.037081538,0.005515416,-0.023564526,-0.002401342,0.04868198,-0.035446201,-0.087506082,1.216961722,2.512366998,,,,,,,, -4943,K284G,0.009761721,-0.009492509,-0.005113939,-0.008522142,-0.092461612,0.032471881,-0.025707155,0.045230596,-0.008624438,-0.033617729,0.014632712,0.014509484,-0.024737361,0.005783812,-0.022828096,-0.071991424,-0.1129318,1.196506357,2.253408402,,,,,,,, -4944,K284F,-0.065972166,-0.034221412,-0.01915904,-0.117587943,-0.286851229,-0.008126857,-0.081020365,-0.050923966,0.015936925,-0.027179296,-0.041263528,-0.021817568,-0.016500511,-0.05743259,-0.177743296,-0.204696938,-0.369005519,1.460655214,2.126313878,,,,,,,, -4945,K284I,-0.047915061,-0.004677264,0.008121187,0.007687492,-0.514835422,0.032596239,-0.056873817,-0.038956305,-0.056263646,0.089189688,-0.098544216,0.114206104,-0.097963731,0.069152347,-0.053777364,-0.217600885,-0.812069959,1.017217977,1.842626241,,,,,,,, -4946,K284H,-0.027958999,0.013219203,0.042184872,0.01037147,-0.005217661,0.028335074,-0.058262131,0.002344133,-0.026491815,-0.01062156,0.037059966,0.079750958,0.004618786,0.025085209,-0.004342269,0.016745609,-0.02718093,1.200113388,2.611282903,,,,,,,, -4947,K284M,0.039465525,-0.018350618,-0.032598517,-0.052190732,-0.107795746,-0.003712866,0.004173865,0.074757184,-0.032671043,-0.058862659,0.022161424,-0.045925834,-0.019271199,-0.064225399,-0.040156065,-0.096675394,-0.118916097,1.369948383,2.282464032,,,,,,,, -4948,K284L,-0.030876035,-0.005206454,0.004979038,0.000922447,-0.044259464,0.051762104,-0.064098921,0.002346851,-0.00201594,0.000140074,-0.010552981,0.012523693,-0.002565618,0.016421316,-0.014576423,-0.051654697,-0.03686423,1.403794308,2.51319102,,,,,,,, -4949,K284N,-0.005976686,-0.054977826,-0.017956623,-0.063212299,-0.074528787,-0.011069381,-0.032354044,0.020400672,0.007503757,-0.078676345,-0.031279307,-0.024302534,-0.011610712,-0.06775838,-0.058666218,-0.11145271,-0.037604863,1.279133157,2.119113416,,,,,,,, -4950,K284Q,0.003224956,-0.036001727,-0.048279694,-0.006757083,-0.071555783,0.049682372,-0.037211358,0.043661269,-0.00904615,-0.067012131,-0.004991322,-0.071459227,-0.025100161,-0.053629752,0.040115587,-0.105303744,-0.037807822,1.61037071,2.4644736,,,,,,,, -4951,K284P,-0.039515673,-0.002604062,-0.199204388,-1.59051964,-2.593265847,0.032548807,-0.051037427,-0.027993918,-0.039058728,-0.015559469,0.010351346,-0.04020411,-0.358204666,-1.312285352,-1.868753928,-2.376104098,-2.810427596,0.959654553,0.748398298,,,,,,,, -4952,K284S,0.019029421,0.010499555,0.003344206,0.016708824,-0.020231824,0.035576829,-0.018134999,0.056193841,-0.006438312,0.00108266,0.01991645,0.027294527,-0.020606115,0.046767599,-0.013349951,-0.027272464,-0.013191183,1.380401521,2.613084933,,,,,,,, -4953,K284R,0.029148916,0.009022217,0.004103836,0.017886226,-0.041719978,0.019733564,-0.014501422,0.072799254,-0.00243367,0.021426346,-0.003381912,0.041838686,-0.033631014,0.059935774,-0.024163322,-0.019150975,-0.064288981,1.130658869,2.487209058,,,,,,,, -4954,K284T,-0.012975183,-0.023907811,-0.012975258,-0.042232718,-0.090440961,0.029528653,-0.037955704,0.012005338,-0.000845933,-0.03806444,-0.009751182,-0.022809471,-0.003141044,-0.015327313,-0.069138122,-0.082459895,-0.098422027,1.281367367,2.270237021,,,,,,,, -4955,K284W,-0.016195725,0.00863963,0.003623166,-0.021032951,-0.449884673,0.04982133,-0.062543173,0.030151723,-0.007421921,-0.008298999,0.025578259,0.016236738,-0.008990407,-0.00421365,-0.037852251,-0.312814583,-0.586954763,1.145886887,1.77664944,,,,,,,, -4956,K284V,-0.027768053,0.002076382,-0.00975478,0.012846875,-0.261296948,0.014595059,-0.049508061,-0.006028045,0.043468785,0.023254405,-0.019101642,0.017752773,-0.037262333,0.024574407,0.001119342,-0.176720362,-0.345873533,1.42533513,2.198468251,,,,,,,, -4957,K284Y,-0.00451025,-0.011810131,0.023828214,0.011551488,-0.111472262,-0.016285369,-0.030725517,0.021705018,-0.011562315,-0.010912194,-0.012708067,0.032238096,0.015418331,0.008925313,0.014177662,-0.083951464,-0.13899306,1.253507871,2.257540566,,,,,,,, -4958,H285A,-0.046267157,-0.052390898,0.012269419,-0.045715169,-0.465274388,0.080088467,-0.040147017,-0.052387296,-0.064010873,-0.048071383,-0.056710412,0.002874559,0.021664279,-0.023498759,-0.067931578,-0.306232018,-0.624316758,1.336543004,1.902832985,,,,,,,, -4959,H285C,-0.027152108,-0.07850001,-0.082541639,-0.060775824,-0.251095353,0.079985056,-0.027705358,-0.026598858,-0.124907305,0.010243541,-0.167243561,-0.114337169,-0.050746108,-0.025817866,-0.095733782,-0.146931349,-0.355259356,1.550802741,2.320464894,,,,,,,, -4960,H285E,-0.04668786,-0.077489954,-0.057370818,-0.083205007,-0.338761709,-0.011353925,-0.017635662,-0.075740057,-0.026848863,-0.049955342,-0.105024566,-0.044883499,-0.069858136,-0.056825172,-0.109584841,-0.262738058,-0.414785359,1.200128361,1.874139605,,,,,,,, -4961,H285D,-0.064282928,-0.082233998,-0.027357107,-0.025369134,-1.535460946,0.121029753,-0.047387509,-0.081178346,-0.098661203,-0.017597391,-0.146870605,-0.008108886,-0.046605327,-0.00703111,-0.043707158,-1.223209889,-1.847712002,0.584649467,1.328290672,,,,,,,, -4962,H285G,-0.03437017,-0.034153432,-0.013024638,-0.02675492,-0.50993699,0.090507129,-0.022940508,-0.045799832,-0.067304919,-0.021596974,-0.046709889,0.00076758,-0.026816855,-0.024677812,-0.028832027,-0.280781037,-0.739092942,1.107088895,1.743985783,,,,,,,, -4963,H285F,0.006117896,-0.036883347,-0.024579855,-0.048331434,-0.149276371,0.111286918,0.071738573,-0.059502781,0.024400853,-0.066565802,-0.007200891,-0.05094427,0.00178456,-0.057803082,-0.038859785,-0.086541722,-0.21201102,1.573480749,2.526964858,,,,,,,, -4964,H285I,-0.052110944,-0.108262475,-0.016498274,-1.23904755,-2.723116824,-0.004294424,-0.016216063,-0.088005824,-0.059604628,-0.122488823,-0.094036127,-0.051102167,0.018105619,-0.900426503,-1.577668597,-2.759185255,-2.687048392,1.03424844,0.831650997,,,,,,,, -4965,H285K,-0.029627249,-0.009882353,-0.03269644,-0.050791848,-0.271887231,0.015611008,-0.024860776,-0.034393721,-0.109009218,0.011815511,-0.031580216,0.01232229,-0.07771517,-0.012094987,-0.089488709,-0.165372451,-0.37840201,1.158000938,1.952331174,,,,,,,, -4966,H285M,-0.081040735,-0.036226921,-0.015397395,-0.065995181,-0.226841047,0.04186132,-0.070107086,-0.091974384,-0.028012836,0.014937559,-0.0873914,0.022134445,-0.052929235,-0.04576579,-0.086224571,-0.100257763,-0.35342433,1.453731894,2.363739969,,,,,,,, -4967,H285L,-0.069336279,-0.035497166,-0.02413953,-0.029208635,-0.553995627,0.077208835,-0.043290227,-0.095382331,-0.058612123,-0.020165842,-0.050828489,-0.001306711,-0.046972349,-0.022405495,-0.036011774,-0.376965626,-0.731025627,1.060233778,1.654608708,,,,,,,, -4968,H285N,0.021839973,0.038751369,-0.005295227,-0.043686901,0.024088321,0.06034565,0.027459507,0.016220438,-0.075757703,0.031753077,0.04574966,0.003970216,-0.014560669,0.012393161,-0.099766963,0.067893098,-0.019716456,1.155290124,2.865440283,,,,,,,, -4969,H285Q,-0.029835568,0.003328337,0.057769555,0.013336226,-0.141955412,0.037134086,-0.024020299,-0.035650836,-0.03393331,0.033311942,-0.026655268,0.113061702,0.002477407,0.101224588,-0.074552137,-0.1049178,-0.178993023,1.334330892,2.545821853,,,,,,,, -4970,H285P,-0.079973704,-0.054928174,-0.914168974,-2.113696092,-2.724870193,0.067835534,-0.051419377,-0.108528031,-0.061057116,-0.045898841,-0.063957506,-0.450210971,-1.378126977,-1.901475477,-2.325916707,-2.76323974,-2.686500646,1.616207972,0.760407801,,,,,,,, -4971,H285S,-0.042936011,-0.056729841,-0.018897727,-0.019913888,-0.160348785,0.075993374,-0.020595921,-0.065276101,-0.072624817,-0.041467078,-0.071992604,-0.015794267,-0.022001186,0.00694886,-0.046776636,-0.094238832,-0.226458738,1.314890865,2.280178059,,,,,,,, -4972,H285R,-0.048493939,-0.019034863,-0.017791108,-0.029604352,-0.157191089,0.061143002,-0.037726471,-0.059261406,-0.079473611,0.003770381,-0.041840107,0.00179255,-0.037374766,-0.014884838,-0.044323865,-0.112055885,-0.202326292,1.400457884,2.288350094,,,,,,,, -4973,H285T,-0.055620389,-0.043969708,-0.044884067,-0.054940351,-0.113390602,0.063022922,-0.055436848,-0.05580393,-0.090678626,-0.026670265,-0.061269151,0.003970216,-0.093738349,-0.030304889,-0.079575812,-0.072089658,-0.154691545,1.514346548,2.541142889,,,,,,,, -4974,H285W,-0.055681479,-0.032883943,-0.014249615,-0.054198738,-0.076231453,0.072687403,-0.062485639,-0.048877318,-0.078175787,0.012021459,-0.077789344,-0.015664917,-0.012834312,-0.020387266,-0.088010209,-0.008240715,-0.144222191,1.30233762,2.631740956,,,,,,,, -4975,H285V,-0.038604749,-0.021556971,-0.025822966,-0.038819881,-0.825731449,0.084401481,-0.048253746,-0.028955752,-0.02222136,-0.021360147,-0.021753794,0.007942071,-0.059588003,-0.030127387,-0.047512375,-0.483575343,-1.167887555,1.202967089,1.665454901,,,,,,,, -4976,H285Y,-0.072056969,-0.041721958,-0.083579037,-0.031318184,-0.094685853,0.050036401,-0.055260606,-0.088853331,-0.023220673,-0.022343827,-0.061100088,-0.080035163,-0.08712291,-0.046817004,-0.015819363,-0.0750808,-0.114290905,1.374097325,2.326613476,,,,,,,, -4977,W286A,-0.03794522,-0.322941308,-1.787981671,-1.961408023,-3.178798104,0.076148022,-0.022854453,-0.053035987,-0.026969419,-0.139075073,-0.506807543,-1.534465091,-2.04149825,-1.952554912,-1.970261134,-3.037843642,-3.319752566,2.656269194,1.056615656,,,,,,,, -4978,W286C,-0.044844145,-0.313323858,-1.724001346,-2.096397703,-2.983761815,0.059320785,0.012885924,-0.102574214,-0.0321029,-0.06455608,-0.562091636,-1.608498837,-1.839503855,-1.880460623,-2.312334783,-2.907757405,-3.059766224,2.757086174,1.145064317,,,,,,,, -4979,W286E,-0.060069761,-0.034149636,-0.706144653,-1.904946112,-2.545852462,0.044144947,-0.014809628,-0.105329893,-0.069830349,-0.027899284,-0.040399987,-0.321592411,-1.090696895,-1.793458898,-2.016433325,-2.238899075,-2.852805849,1.485015537,0.761014894,,,,,,,, -4980,W286D,-0.098225732,-0.092319389,-0.991545637,-2.162412268,-2.859106006,0.027078649,-0.048379416,-0.148072048,-0.017223036,-0.096065304,-0.088573474,-0.476826718,-1.506264556,-1.991826552,-2.332997984,-2.47505529,-3.243156722,1.632738385,0.734380347,,,,,,,, -4981,W286G,-0.020285201,-0.023080383,-1.049435316,-2.035040286,-3.228429174,0.060527429,0.011754574,-0.052324976,-0.042765966,-0.046775209,0.000614444,-0.654189172,-1.444681459,-1.879770376,-2.190310196,-2.474149566,-3.982708782,1.933994225,0.860539839,,,,,,,, -4982,W286F,-0.039678789,0.022006699,-0.05139122,-0.035329727,-0.780425279,0.029596279,-0.008837059,-0.070520519,-0.045872716,0.023657577,0.02035582,-0.049465696,-0.053316743,-0.028385328,-0.042274125,-0.414184251,-1.146666306,1.155829645,1.677639804,,,,,,,, -4983,W286I,-0.079611889,-0.002497151,-0.001055027,-1.204237153,-2.429502334,0.060793225,-0.03499656,-0.124227217,-0.042629379,-0.045114732,0.04012043,-0.007004702,0.004894649,-0.63365367,-1.774820635,-2.077115281,-2.781889386,1.699155243,1.344656418,,,,,,,, -4984,W286H,-0.123809877,-0.058729876,-0.039697844,-0.966694359,-1.782739799,-0.008238344,-0.106133802,-0.141485951,-0.04853213,-0.009241173,-0.108218578,-0.016999718,-0.062395969,-0.401665784,-1.531722934,-1.876925592,-1.688554006,1.566215457,1.38598284,,,,,,,, -4985,W286K,-0.024663504,-0.036908804,-0.840789588,-1.817969863,-2.566351628,0.00249217,0.038081734,-0.087408741,-0.110334137,-0.119766548,0.04594894,-0.505116357,-1.176462818,-1.891021495,-1.74491823,-2.918318277,-2.214384979,1.742588391,0.792661469,,,,,,,, -4986,W286M,-0.070083197,-0.026072183,-0.049894946,0.010723905,-1.699781263,-0.042759615,-0.036310236,-0.103856157,-0.032656403,0.011282621,-0.063426987,-0.01722688,-0.082563011,0.056412628,-0.034964819,-1.576971635,-1.82259089,0.612876198,1.312323321,,,,,,,, -4987,W286L,-0.056208465,-0.026258346,-0.043624029,-1.299020745,-2.244688275,0.015539315,-0.022969213,-0.089447716,-0.027575447,-0.025643951,-0.026872741,-0.017836169,-0.069411888,-0.771829807,-1.826211682,-2.150946137,-2.338430412,1.910193482,1.392398102,,,,,,,, -4988,W286N,-0.009794482,-0.054397613,-0.264041511,-1.887312939,-2.584006677,0.00829173,0.050642488,-0.070231451,-0.111642845,-0.087972897,-0.020822329,-0.150411309,-0.377671713,-1.925482531,-1.849143346,-2.408711269,-2.759302084,1.039487314,0.681614117,,,,,,,, -4989,W286Q,-0.051180388,-0.067660309,-0.263159765,-1.672109671,-2.699394131,-0.042502924,-0.024774867,-0.077585909,-0.058757725,-0.064868185,-0.070452432,-0.148447114,-0.377872415,-1.297221353,-2.046997988,-2.043691526,-3.355096735,2.656661711,1.752924673,,,,,,,, -4990,W286P,-0.020773802,-0.032204064,-0.679009198,-1.774133056,-2.793520382,0.027337507,0.020801137,-0.06234874,-0.046381871,-0.052928428,-0.011479699,-0.244191035,-1.11382736,-1.627888729,-1.920377382,-2.550450161,-3.036590602,1.295336592,0.758203241,,,,,,,, -4991,W286S,-0.035005545,-0.110906583,-1.368383906,-2.347502246,-2.967712254,0.049699476,0.003713398,-0.073724487,-0.061768824,-0.024788285,-0.197024881,-1.037578575,-1.699189236,-2.405870928,-2.289133564,-2.463130933,-3.472293574,0.891281326,0.140268785,,,,,,,, -4992,W286R,-0.025876953,-0.012934593,-0.853983933,-1.902060668,-2.707731259,0.021912026,0.006036589,-0.057790495,-0.080176346,-0.039498408,0.013629222,-0.366959649,-1.341008217,-1.801386267,-2.002735068,-2.381525018,-3.033937499,1.49838426,0.760712207,,,,,,,, -4993,W286T,-0.072448841,-0.120705141,-1.316637014,-2.070245121,-2.806421744,0.046943739,-0.00630607,-0.138591611,-0.074702488,-0.012398127,-0.229012154,-1.022829262,-1.610444766,-1.929035722,-2.211454519,-2.380079777,-3.23276371,3.111094417,1.695993707,,,,,,,, -4994,W286V,-0.015917203,-0.03684768,-0.943010715,-1.866516117,-2.813837323,0.02721362,0.029899298,-0.061733704,-0.038513113,-0.039365157,-0.034330203,-0.524840289,-1.361181141,-1.817991373,-1.915040861,-2.535303317,-3.092371328,1.76202265,0.824707313,,,,,,,, -4995,W286Y,-0.057696509,-0.051533859,-0.03460837,-0.043875017,-0.962360954,0.067596206,-0.019271041,-0.096121977,0.02454355,-0.016550427,-0.086517291,0.006978828,-0.076195567,-0.085645488,-0.002104546,-0.681236407,-1.243485501,1.283680001,1.601609905,,,,,,,, \ No newline at end of file diff --git a/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv b/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv deleted file mode 100644 index 3973e5d..0000000 --- a/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled.csv +++ /dev/null @@ -1,4997 +0,0 @@ -,Unnamed: 0,mutant,0,39,156,625,2500,cefotaxime,0_1,0_2,10_1,39_1,39_2,156_1,156_2,625_1,625_2,2500_1,2500_2,km,vmax,mutation_effect_prediction_vae_ensemble,mutation_effect_prediction_vae_1,mutation_effect_prediction_vae_2,mutation_effect_prediction_vae_3,mutation_effect_prediction_vae_4,mutation_effect_prediction_vae_5,mutation_effect_prediction_pairwise,mutation_effect_prediction_independent,esm1v_t33_650M_UR90_1,esm1v_t33_650M_UR90_2,esm1v_t33_650M_UR90_3,esm1v_t33_650M_UR90_4,esm1v_t33_650M_UR90_5 -0,0,H24C,0.022702344,0.045890139,-0.025738193,0.018871156,-0.418259925,-0.031940758,-0.037094619,0.08249930700000001,0.002591313,-0.042346297000000005,0.134126575,-0.010196878000000001,-0.041279508,-0.014684342,0.052426653,-0.31935651800000003,-0.517163332,0.785765464,1.5199638519999998,,,,,,,,,-2.602888584136963,-1.227370262145996,-0.31102609634399414,-2.2438855171203613,-1.2750320434570312 -1,1,H24E,0.011387119,-0.012635759,-0.018954701,-0.0204358,-0.279024169,0.016456013999999998,0.013497391000000001,0.009276846,0.054103653,-0.01967789,-0.005593628000000001,0.0015707420000000002,-0.039480144,-0.034798015,-0.006073584,-0.200042482,-0.358005855,0.757582777,1.502589239,,,,,,,,,-1.4000859260559082,0.17653560638427734,0.7310853004455566,-1.0783019065856934,1.1374282836914062 -2,2,H24D,0.042301356,0.017005294,0.018951436000000002,0.006742876,-0.18160661,-0.030325921000000002,0.033849314,0.050753398,0.0027643740000000004,-0.0074014580000000005,0.041412046,0.017489834,0.020413037,-0.02608598,0.039571732000000005,-0.155937758,-0.20727546100000002,0.763289728,1.622027556,,,,,,,,,-0.8043856620788574,0.11954212188720703,0.316037654876709,-1.021261215209961,0.8015751838684082 -3,3,H24G,0.01146042,-0.024511458,-0.023807149,-0.01720911,-0.060241672999999996,-0.009657341,-0.00047182699999999997,0.023392666,-0.013742003000000001,-0.040919201,-0.008103714,-0.02192628,-0.025688017999999996,-0.028224614,-0.006193606,-0.043527004,-0.076956341,1.099627807,1.7369408569999998,,,,,,,,,-1.6988272666931152,0.6679954528808594,0.6457986831665039,-0.9878940582275391,0.6070022583007812 -4,4,H24F,0.020598952,0.020320945,-0.015905298000000002,0.016190193000000002,-0.8184870959999999,-0.0008093110000000001,0.021397398999999998,0.019800504,-0.0015906879999999998,-0.045411124000000004,0.086053014,-0.01345311,-0.018357485,-0.008856131,0.041236516,-0.493981846,-1.142992345,1.074944348,1.5749229180000002,,,,,,,,,-1.6305785179138184,0.41070985794067383,0.5096173286437988,-1.2065320014953613,0.5256252288818359 -5,5,H24I,0.008072384,-0.002722445,-0.039291543,-0.00968701,-0.359191243,-0.009312377,-0.0016294979999999998,0.017774265,-0.068626848,-0.019115145,0.013670255,-0.032591788999999996,-0.045991295999999994,-0.027839389,0.008465369,-0.292563068,-0.42581941700000003,0.8479204020000001,1.5187357940000001,,,,,,,,,-1.105363368988037,0.0135040283203125,0.9754328727722168,-1.1068305969238281,0.5528297424316406 -6,6,H24K,0.039887617,-0.002490981,-0.019397018999999998,0.00610538,0.014469576999999999,-0.003065117,0.052906255,0.026868977999999998,0.16419203599999999,-0.019079923999999998,0.014097962,-0.013887172,-0.024906865,-0.007384305999999999,0.019595066,0.029525026,-0.000585873,0.326024656,1.4161181809999999,,,,,,,,,-1.4430279731750488,0.2781662940979004,0.4867582321166992,-1.2569799423217773,0.5253987312316895 -7,7,H24M,0.025373797000000003,0.012340427,0.024713301,0.028739506,-0.22478129300000002,-0.026146539,0.02684011,0.023907484,0.18267544100000002,-0.006794296,0.031475149,0.00551956,0.043907042,0.010168857,0.04731015400000001,-0.146503843,-0.303058742,1.110067341,1.8944240630000002,,,,,,,,,7.845651626586914,8.054424285888672,7.501232147216797,5.750218391418457,7.447070121765137 -8,8,H24L,-0.007130208000000001,-0.024791695,-0.011061763,-0.011754145,-0.480346576,-0.001964848,-0.010297589000000001,-0.003962826,0.00735616,-0.009807279,-0.03977611,0.009071989,-0.031195515,-0.006225547,-0.017282742,-0.306059807,-0.654633344,1.023505724,1.645245487,,,,,,,,,-0.11063623428344727,1.1941204071044922,1.7156176567077637,-0.5725469589233398,1.18654203414917 -9,9,H24N,0.007222492,-0.010835478,0.016865981999999998,0.007656296999999999,-0.043093163,-0.008911973,-0.002849495,0.017294478999999998,0.08085483,-0.010625522,-0.011045434,0.01749522,0.016236743999999997,-0.014733888,0.030046481,-0.006558291999999999,-0.079628033,0.9955250659999999,2.060699369,,,,,,,,,-0.8150019645690918,0.4620952606201172,0.5903453826904297,-1.6611976623535156,0.29015350341796875 -10,10,H24Q,0.006029993000000001,-0.008585199,0.0049857190000000004,-0.016438516,-0.135568334,0.001497615,0.00969967,0.002360316,-0.013783367,-0.010388462,-0.006781935,0.011864976000000001,-0.0018935389999999999,-0.033507197999999995,0.000630166,-0.08476713400000001,-0.186369533,2.437793081,2.747970799,,,,,,,,,0.25345849990844727,0.4092268943786621,0.469515323638916,-1.0112266540527344,0.658299446105957 -11,11,H24P,-0.13387458300000002,-0.082345722,-0.072931638,-0.417904623,-1.010848138,0.67096666,-0.112957484,-0.15479168199999999,-0.744292983,-0.129206405,-0.035485037999999997,-0.084989922,-0.060873354000000005,-0.19933237,-0.636476876,-0.924415785,-1.097280491,2.983480558,2.7878750510000003,,,,,,,,,-0.5790095329284668,1.157853126525879,1.612807273864746,-0.3851461410522461,1.5412368774414062 -12,12,H24S,-0.008154446999999999,-0.034115248,-0.020574225,-0.01582124,0.036166097,0.0027934640000000003,-0.024719945,0.008411051,-0.018904125,-0.030762357,-0.037468138,0.013887271999999999,-0.055035722,-0.013632758,-0.018009721,0.068115045,0.004217149,2.225154604,2.659353477,,,,,,,,,-0.6207737922668457,0.8913359642028809,1.3759241104125977,-0.7207245826721191,1.3725676536560059 -13,13,H24R,0.01683236,-0.009190524,0.004127683,-0.004182925,-0.002526258,0.031088453999999998,0.017507484,0.016157236000000002,-0.079373389,-0.029775986,0.011394938,0.006579872,0.001675493,-0.023271806000000003,0.014905956000000001,-0.008315396999999999,0.0032628809999999996,1.5464736069999998,2.938183126,,,,,,,,,-1.8611407279968262,0.5960955619812012,0.8922905921936035,-1.1381635665893555,0.6326322555541992 -14,14,H24T,0.02039927,-0.01458811,-0.007601924,-0.0047955820000000005,-0.067187546,-0.022489462999999998,0.018380054,0.022418486,-0.00299271,-0.037083702999999996,0.007907483,-0.000237405,-0.014966443000000001,-0.016221578,0.006630414,-0.04873158,-0.08564351199999999,1.407678003,2.285347998,,,,,,,,,-0.45914125442504883,0.8859066963195801,1.370063304901123,-1.2340259552001953,1.123603343963623 -15,15,H24W,-0.006307298,-0.000633045,-0.029192701,-0.010615592,-1.3475859609999998,-0.015026478000000001,-0.006286516,-0.00632808,-0.038247647999999995,-0.036022839,0.034756748999999997,-0.031301744,-0.027083657999999997,-0.030208582999999997,0.0089774,-0.999196822,-1.695975099,1.04687351,1.421552326,,,,,,,,,-3.2982287406921387,-1.0799760818481445,-1.0270228385925293,-2.9282422065734863,0.1146860122680664 -16,16,H24V,0.026710717999999998,-0.010529573,-0.005339989,0.006753803,-0.026874047,-0.005140612,0.022703225,0.03071821,0.05573437,-0.015589325,-0.005469821,-0.013335158,0.00265518,-0.013740954,0.02724856,-0.001619701,-0.052128392999999995,1.224564307,2.138393446,,,,,,,,,-0.16326475143432617,0.8327455520629883,1.381129264831543,-0.6579561233520508,1.15031099319458 -17,17,H24Y,-0.021573751000000002,-0.047011483,-0.023488167999999997,-0.033551258,-0.88502515,-0.015438488,-0.030115287999999997,-0.013032213,-0.034730469,-0.048617680999999996,-0.045405285,-0.006905626,-0.04007071,-0.038534926000000004,-0.02856759,-0.5889599870000001,-1.181090312,1.9215416580000002,2.138059625,,,,,,,,,-2.2190871238708496,0.22927570343017578,2.36281681060791,-1.7589797973632812,0.11054039001464844 -18,18,P25A,-0.10386603800000001,0.001748125,-0.004218662,-0.053582423,-1.6425950930000002,0.120518217,-0.083327717,-0.124404359,0.014370958,0.034530088,-0.031033839,0.032673877000000004,-0.041111199999999994,-0.036225351,-0.070939495,-1.430707001,-1.854483185,2.467386436,2.150571057,,,,,,,,,-2.6970016956329346,-2.8042426109313965,-2.2496190071105957,-2.491567373275757,-2.352628231048584 -19,19,P25C,-0.035211365,0.08671240300000001,-0.06833471099999999,0.009652236,-0.364138405,0.12798769999999998,-0.020434406000000002,-0.049988324,-0.054549701,0.101310071,0.072114734,-0.191309107,0.054639685,0.047170985,-0.027866513,-0.195560504,-0.532716305,1.9294107,2.312449074,,,,,,,,,-7.236415863037109,-7.3394455909729,-6.767462730407715,-7.342309951782227,-6.836550712585449 -20,20,P25E,-0.011457153999999999,0.041199839,-5.429999999999999e-05,-0.010716763999999998,0.143257861,0.111450601,0.02865962,-0.051573928,-0.074597621,-0.01477754,0.09717721800000001,-0.00321029,0.00310163,-0.008045502,-0.013388026,0.149960974,0.136554748,1.590983034,3.812283434,,,,,,,,,-3.2850844860076904,-4.4464874267578125,-4.056534290313721,-4.006731986999512,-4.110268592834473 -21,21,P25D,0.004797193,0.025658574,-0.060980488,-0.037705233,-0.028402505,0.046607841,-0.006968291,0.016562676999999998,-0.029385042000000004,0.006194666,0.045122482,-0.06390813099999999,-0.058052845,-0.028843079,-0.046567387,0.016735672,-0.073540682,1.165591923,1.75016223,,,,,,,,,-3.061547040939331,-3.6416678428649902,-3.4436025619506836,-3.780508518218994,-3.8518667221069336 -22,22,P25G,-0.02390934,0.00857487,0.02089776,-0.007906311999999999,-0.969267861,0.039196438,-0.01376224,-0.034056439,0.015377403000000001,-0.013636435,0.030786175,0.0070737280000000005,0.034721791,-0.011556967,-0.004255656,-0.649078606,-1.289457116,1.174220101,1.5674038019999998,,,,,,,,,-4.4943695068359375,-4.695700168609619,-4.18939208984375,-4.418043613433838,-4.31758975982666 -23,23,P25F,-0.012487661,-0.042772745,0.07568559799999999,0.033886087999999995,-0.19980403100000002,0.066925464,-0.049121473,0.024146152,0.10149363800000001,0.003571726,-0.089117216,0.083675768,0.067695427,0.024388933999999998,0.043383240999999996,-0.137551135,-0.262056927,0.9640241759999999,1.7040422309999999,,,,,,,,,-5.142892837524414,-5.116181373596191,-4.85345458984375,-5.524085998535156,-4.9148173332214355 -24,24,P25I,-0.028071818,0.024272005,0.016421708,0.02703638,-0.073523836,0.021876117,0.048925754,-0.10506939,-0.04549523900000001,0.030187245,0.018356763999999998,0.070782746,-0.037939331,0.001924393,0.052148365999999995,-0.047404682000000004,-0.09964299,0.49533926100000003,1.521717066,,,,,,,,,-4.134558200836182,-4.586539268493652,-3.7875375747680664,-4.52031135559082,-4.105124473571777 -25,25,P25H,0.029477972999999998,0.040318718999999996,0.06397124900000001,0.07258627,0.045784618,0.07333674,0.013637671,0.045318274000000006,-0.0032417120000000003,0.074293521,0.006343916,0.08378065700000001,0.04416184099999999,0.137057045,0.008115495,0.10669228300000001,-0.015123046999999999,0.39783476799999995,1.463720776,,,,,,,,,-3.7110583782196045,-4.491919994354248,-4.0179123878479,-4.553029537200928,-4.564919471740723 -26,26,P25K,-0.066288891,0.11725209199999999,0.009166947,0.072576088,0.135590499,0.020043081,-0.02721235,-0.105365432,-0.006021205999999999,0.116714876,0.11778930800000001,0.042032785999999996,-0.023698892000000003,0.154531417,-0.009379241,0.153679558,0.11750144,0.8460874890000001,1.542000952,,,,,,,,,-2.836686611175537,-4.006977081298828,-3.505506992340088,-3.59694504737854,-3.7610931396484375 -27,27,P25M,-0.09282261,0.029051416,0.006452596999999999,0.039816967,-0.02836574,0.050932846,-0.052520568,-0.13312465099999998,0.040635807999999995,0.050526799000000004,0.007576032,0.060013935,-0.047108740999999996,0.11788607400000001,-0.03825214,0.010015825,-0.066747305,0.188973702,1.759942865,,,,,,,,,-5.370996952056885,-5.49267053604126,-4.631115913391113,-5.3990702629089355,-5.0046067237854 -28,28,P25L,-0.005307256,0.002001949,0.011836247,0.008659517,-0.211868922,0.064513297,-0.002101309,-0.008513203,0.015368952,0.00376092,0.00024297700000000002,-0.002386983,0.026059476,0.04727512,-0.029956087000000003,-0.122705077,-0.301032767,1.945234964,2.369792706,,,,,,,,,-3.783540964126587,-4.444002628326416,-3.665452480316162,-4.193267345428467,-3.7988052368164062 -29,29,P25N,-0.051559887,0.039733466,0.070335003,0.004724437,0.020640486,0.036064768999999997,0.031452377000000004,-0.13457215,-0.027886684,-0.035975711,0.115442642,0.031178817999999997,0.10949118699999999,0.01069026,-0.001241387,0.014249976999999999,0.027030995,1.104388073,2.143068318,,,,,,,,,-2.313053607940674,-2.8003196716308594,-2.342251777648926,-3.1996471881866455,-3.1156206130981445 -30,30,P25Q,0.138010463,0.011568189,0.063431807,0.10837302900000001,-0.028213622,0.07860940200000001,0.091898126,0.18412279899999998,0.032167147,0.021135016,0.002001361,0.020337831,0.106525782,0.064379082,0.152366976,-0.019924656000000002,-0.036502587,1.208210385,2.58900106,,,,,,,,,-2.691493272781372,-3.337177276611328,-2.556959629058838,-2.82781720161438,-3.5837783813476562 -31,31,P25S,-0.039348434,0.004380082,-0.0039446590000000005,-0.018238771,-0.160130436,0.030006567,-0.013738251000000002,-0.064958616,-0.055818152,-0.026092677999999998,0.034852842,0.018987832,-0.026877149,0.006671651,-0.043149192,-0.150924537,-0.169336335,1.406720565,2.237189096,,,,,,,,,-1.8970792293548584,-2.1925277709960938,-2.0608034133911133,-2.6042063236236572,-2.6614346504211426 -32,32,P25R,-0.013706154,0.005957286,-0.014669933000000001,-0.046117530999999996,0.054153993,0.156314831,-0.000248097,-0.02716421,-0.089279396,-0.021879775,0.033794347,-0.029032602,-0.000307263,-0.098906076,0.006671015,-0.0028679779999999998,0.111175963,1.251916214,2.535180898,,,,,,,,,-4.026546955108643,-4.291104316711426,-4.098500728607178,-4.097418785095215,-3.89284086227417 -33,33,P25T,-0.076933927,-0.007848001,-0.006919319,0.0010241360000000001,-0.091199948,0.000353426,-0.026131054,-0.127736799,-0.017982202,0.00335265,-0.019048652,-0.009112019,-0.004726618,0.013580426999999999,-0.011532155,-0.04988034,-0.13251955599999998,1.24094672,2.425970024,,,,,,,,,-2.39045786857605,-2.652970314025879,-2.4135191440582275,-2.7792909145355225,-2.92512845993042 -34,34,P25W,0.013600484,0.050044448,0.073206825,0.029595033,-0.109138595,0.030245566,-0.0032214559999999997,0.030422422999999997,0.0039723729999999995,0.061866422000000004,0.038222474,0.024107117999999997,0.122306531,0.045284397000000004,0.013905668000000001,-0.051122111,-0.167155079,1.169687228,2.435839065,,,,,,,,,-7.465410232543945,-7.624284744262695,-7.609542369842529,-7.139909267425537,-7.192192077636719 -35,35,P25V,-0.027791512999999997,0.025620063,0.022951329,-0.010637381999999999,0.04591299099999999,0.100840981,-0.022572752,-0.033010274,-0.052321226,0.014312122,0.036928004,0.015046283999999998,0.030856374,-0.011038731000000001,-0.010236033,0.047570830999999994,0.04425515,1.1290397890000001,2.788424151,,,,,,,,,-4.596778869628906,-4.739037036895752,-3.8129396438598633,-4.527744293212891,-4.248297214508057 -36,36,P25Y,-0.094727201,-0.008258924,-0.022609935,-0.03167515,0.0017446679999999998,-0.082969713,-0.136345006,-0.053109395,0.015099743999999998,-0.0036885679999999997,-0.01282928,0.029174482999999998,-0.074394353,-0.013321733,-0.050028567,-0.0063045490000000004,0.009793885,1.2289840570000001,2.5370460969999997,,,,,,,,,-5.7128214836120605,-5.8133392333984375,-5.407821178436279,-6.2942094802856445,-5.611146450042725 -37,37,E26A,-0.060088714,0.035019974,0.046008999999999994,0.07483489900000001,0.010913108000000001,0.07026014900000001,-0.06167179,-0.058505638,0.090042438,-0.011974944,0.082014892,0.03097157,0.061046429000000006,0.023863482000000002,0.125806315,-0.011478437,0.033304653,1.2204184059999998,2.754342831,,,,,,,,,-4.355764389038086,-3.518104076385498,-3.1532793045043945,-3.244997978210449,-3.2319722175598145 -38,38,E26C,0.051185296,0.08338335200000001,0.07888178700000001,0.072504124,-0.158232612,-0.067113079,0.061477542999999996,0.040893049,0.147844696,-0.0041502859999999996,0.17091699,0.024473769,0.133289805,0.031847367,0.11316088,-0.147334969,-0.16913025399999998,1.319927096,2.178389478,,,,,,,,,-9.489402770996094,-7.842201232910156,-8.109064102172852,-9.433377265930176,-8.090197563171387 -39,39,E26D,-0.134622252,-0.048278454000000005,0.029866107000000003,0.027840852000000003,-0.07578524,0.083496095,-0.12736836199999998,-0.14187614199999998,0.08222078299999999,-0.128399269,0.031842361,0.049190665999999994,0.010541547,-0.009290076,0.06497178,-0.073498399,-0.078072081,1.160453271,2.203032084,,,,,,,,,-3.460214614868164,-2.7330234050750732,-3.364128828048706,-2.161895275115967,-3.0149898529052734 -40,40,E26G,0.074308788,0.223560228,0.17184728800000001,0.179592065,0.08131007700000001,-0.027626518,0.012129959,0.136487616,0.172252043,0.146756386,0.30036407,0.16478736800000002,0.17890720699999998,0.13317435,0.226009779,0.06361610200000001,0.099004051,1.189518643,2.987475843,,,,,,,,,-5.775092124938965,-4.524786949157715,-4.528716564178467,-4.766471862792969,-4.672470569610596 -41,41,E26F,-0.020927228,0.052075812,0.062112092,0.085250613,-0.232106116,-0.10336064,-0.017165364,-0.024689091,-0.06504592099999999,0.065483923,0.0386677,0.113509275,0.010714908,0.12774971400000001,0.042751512,-0.091720963,-0.372491268,1.1686604999999999,2.305963479,,,,,,,,,-7.110034942626953,-5.979201316833496,-5.943520545959473,-6.823481559753418,-4.3956122398376465 -42,42,E26I,-0.04678198099999999,0.08923668400000001,0.089213575,0.103174965,-0.153907493,-0.044398892,-0.072168265,-0.021395696000000002,0.130412738,0.07330538,0.10516798699999999,0.08943488,0.088992269,0.117652059,0.08869787,-0.138097757,-0.169717228,1.252476759,2.191690605,,,,,,,,,-5.983729362487793,-4.881807327270508,-4.888604640960693,-5.386773109436035,-3.953732490539551 -43,43,E26H,-0.043425119000000005,0.082855565,0.083513347,0.114422615,0.020916837,0.010849126,-0.086416719,-0.00043351800000000003,0.07944541,0.049495962000000004,0.11621516800000001,0.085745016,0.081281677,0.113490903,0.11535432699999999,0.025989434,0.015844239,1.261017122,3.025741946,,,,,,,,,-6.1391730308532715,-5.359552383422852,-5.375854969024658,-5.458864212036133,-5.230713844299316 -44,44,E26K,-0.038926874,0.058490223,0.039393067999999996,0.08651887800000001,0.087119809,0.041040865,-0.046154832,-0.031698916,0.154969402,-0.0632611,0.180241545,-0.001884144,0.08067028,0.018855342,0.154182414,0.011954356999999999,0.16228526,1.090470615,2.610276223,,,,,,,,,-5.291767120361328,-4.606650352478027,-4.287993907928467,-4.36334228515625,-4.296318054199219 -45,45,E26M,-0.022183283999999998,0.074443098,0.09094756,0.118748545,-0.036440986,-0.053481152000000004,0.011119258,-0.055485825,0.306981506,0.08346328900000001,0.065422907,0.145623335,0.036271785,0.130202977,0.10729411300000001,-0.005214771,-0.067667201,1.218124703,2.7516917419999998,,,,,,,,,-7.316380023956299,-5.909694194793701,-5.760078430175781,-6.123344421386719,-5.121820449829102 -46,46,E26L,0.010543748,0.08294438900000001,0.076037929,0.091447172,-0.05818041,-0.021525499,0.000614657,0.020472838,0.099935417,0.003116839,0.162771939,0.048573675999999996,0.103502182,0.004616994,0.17827735,-0.079421767,-0.036939052,1.135646515,2.2157617259999998,,,,,,,,,-5.333183765411377,-4.372880458831787,-4.456526756286621,-4.7450761795043945,-3.4744555950164795 -47,47,E26N,-0.031657324,0.060627192,0.091066853,0.039984992000000004,-0.006468796999999999,-0.053321327,-0.04427469999999999,-0.019039948,0.229094262,-9.49e-05,0.121349284,0.127210553,0.054923152999999995,-0.013103046,0.093073029,0.018903217,-0.03184081,1.204694658,2.929347525,,,,,,,,,-4.698429107666016,-3.6432738304138184,-3.9799187183380127,-3.25057315826416,-3.4677770137786865 -48,48,E26Q,-0.020517156,0.08404489,0.04875523,0.064826026,0.049690653,-0.005371125,0.000764699,-0.041799011000000004,-0.00472684,0.098069679,0.070020101,0.100251745,-0.002741286,0.08672771,0.042924342000000004,-0.047413247,0.146794553,1.215644385,2.5650320769999997,,,,,,,,,-4.613254547119141,-3.6933701038360596,-3.5244128704071045,-2.5107932090759277,-3.828115940093994 -49,49,E26P,-0.013258715,0.093119437,0.069852749,0.066757808,-0.387232365,-0.010640993999999999,-0.020444549,-0.00607288,0.121882909,0.034911035,0.15132783800000002,0.048987795,0.090717702,0.028017465,0.105498151,-0.323835808,-0.45062892200000004,0.8622878490000001,1.5888088130000002,,,,,,,,,-5.902938365936279,-4.18911600112915,-4.101150035858154,-4.418404579162598,-3.7045068740844727 -50,50,E26S,0.008822045,0.062530196,0.084343423,0.066269137,-0.039584928,-0.00190877,0.015906523,0.001737566,0.093909764,0.01396951,0.111090881,0.037997407000000004,0.130689439,0.018650728000000002,0.11388754599999999,-0.063170402,-0.015999453,1.425051198,2.4730023969999997,,,,,,,,,-4.548834800720215,-3.041699171066284,-3.244539260864258,-3.267892360687256,-3.218538999557495 -51,51,E26R,-0.034878101,0.064167344,0.056959895999999996,0.064815187,-0.220002694,0.055094485,-0.04941712,-0.020339081999999998,0.06200121,0.001093115,0.127241572,0.019034356000000002,0.094885435,0.016606558,0.113023815,-0.233019957,-0.20698543,1.216399974,1.927173917,,,,,,,,,-6.591220378875732,-5.471687316894531,-5.567778587341309,-5.545095443725586,-5.136788368225098 -52,52,E26T,-0.068693308,0.067196764,0.091103084,0.06558067299999999,-0.135908892,-0.047085287,-0.082941395,-0.054445220999999995,0.140445519,0.040813172,0.09358035599999999,0.113968603,0.068237565,0.063663484,0.06749786099999999,-0.126344867,-0.14547291699999998,1.342091145,2.282051505,,,,,,,,,-4.799383640289307,-3.561384916305542,-3.558928966522217,-3.739595651626587,-3.448068380355835 -53,53,E26W,-0.077143388,0.078134304,0.13106215599999999,0.05794898,-0.442340179,-0.007556826,-0.099702913,-0.054583862999999996,0.127188408,0.107484662,0.048783945,0.158286969,0.10383734300000001,0.076026447,0.039871512000000005,-0.282806958,-0.601873399,0.753185228,1.5744139519999998,,,,,,,,,-8.960208892822266,-8.442667007446289,-8.384608268737793,-8.660918235778809,-6.680573463439941 -54,54,E26V,-0.021916136,0.116771963,0.09809352199999999,0.07620685599999999,-0.06456742900000001,0.053498727999999995,0.0013647870000000001,-0.045197059000000005,-0.005312536999999999,0.054057513,0.17948641199999998,0.095287693,0.10089935,0.063602831,0.08881088,-0.0759068,-0.053228057,1.14355857,2.2914504630000003,,,,,,,,,-5.796435356140137,-4.568323612213135,-4.226870536804199,-4.804082870483398,-3.896843433380127 -55,55,E26Y,-0.050049098,0.056360349000000004,0.082999386,0.068513351,-0.245436276,0.008291246,-0.053024215,-0.04707398,0.16999146899999998,0.029324085,0.083396613,0.065728571,0.1002702,0.026829566000000003,0.110197135,-0.13169476800000002,-0.359177783,1.238381025,2.122608572,,,,,,,,,-7.852902412414551,-6.692204475402832,-6.658698558807373,-7.590540885925293,-5.7663140296936035 -56,56,T27A,0.01357957,0.039949606,0.057111746,0.013452565,-1.4545883080000002,0.032397485,0.017141401,0.010017739,-0.035744448,0.005885989,0.074013222,0.050484312999999996,0.063739178,0.038931638,-0.012026509,-1.3270744909999999,-1.582102125,0.584924165,1.322045675,,,,,,,,,-3.9810473918914795,-3.6764276027679443,-3.1769416332244873,-2.8085618019104004,-3.4692797660827637 -57,57,T27C,0.018866531000000002,0.064055143,0.05501894400000001,-0.16464778900000002,-2.419022561,-0.02408756,-0.000750725,0.038483787,-0.087721879,0.025631016,0.10247927,0.074124041,0.035913847,-0.064575672,-0.264719906,-1.851261728,-2.9867833939999997,0.7824591359999999,1.307603573,,,,,,,,,-7.645715713500977,-6.079275131225586,-7.259165287017822,-7.184093475341797,-7.572291851043701 -58,58,T27E,-0.060106353,-0.035422838,-0.7334358529999999,-2.0218939430000002,-2.414464268,-0.084510018,-0.055243239000000006,-0.06496946599999999,-0.05644945,-0.028293325,-0.042552350999999995,-0.340185302,-1.126686403,-1.937002238,-2.1067856469999997,-2.048521205,-2.780407331,1.6019825730000001,0.765758664,,,,,,,,,-5.59326171875,-5.001279830932617,-5.0537309646606445,-5.344027042388916,-5.168048858642578 -59,59,T27D,-0.052200116,-0.017669463,-0.013005533,-1.445405769,-2.29488302,0.05915248,-0.034762106,-0.069638126,-0.036020585,-0.008402157,-0.026936769,-0.017412133,-0.008598933000000001,-0.8905929370000001,-2.0002186,-1.961683246,-2.628082794,2.181692184,1.551446707,,,,,,,,,-5.131093978881836,-4.654732704162598,-4.832296848297119,-5.078575134277344,-4.911919593811035 -60,60,T27G,-0.05851333,0.071181742,-0.028860278,-1.681217301,-2.356711536,-0.01488177,-0.058640051,-0.058386609000000006,-0.07887849799999999,0.081791089,0.060572394,-0.002275716,-0.05544484,-1.3868884469999998,-1.975546154,-2.206922736,-2.506500335,0.772049338,0.719134598,,,,,,,,,-6.2565016746521,-5.452259063720703,-4.97437047958374,-4.973968029022217,-5.610524654388428 -61,61,T27F,-0.046006795999999996,-0.03043394,-0.012103451000000001,-1.582760741,-2.604569889,-0.046856321,-0.045534145,-0.046479447,-0.09075764900000001,-0.023318534,-0.037549346000000004,0.027109167000000003,-0.051316068,-1.1836745709999998,-1.98184691,-2.3495512,-2.859588577,0.969364977,0.766731288,,,,,,,,,-3.8111045360565186,-3.032863140106201,-3.2538909912109375,-3.1513023376464844,-3.8868465423583984 -62,62,T27I,0.023747147000000003,0.051240129,0.075382693,0.023093952999999997,-0.280445552,0.004405203,0.002991707,0.044502587,0.054869759000000004,-0.008443589,0.11092384599999999,0.032435341,0.11833004400000001,0.068619705,-0.022431799,-0.213844297,-0.347046807,1.131320058,1.907965161,,,,,,,,,-3.281839370727539,-2.4055676460266113,-3.0174150466918945,-2.89418888092041,-2.7953643798828125 -63,63,T27H,-0.025521534,0.054516839000000004,0.033160455,-0.247634362,-1.849536455,-0.015516528,-0.023085744,-0.027957324,-0.050290329,0.063741083,0.045292595,0.042622928,0.023697982000000003,-0.20539605600000002,-0.289872668,-1.689638244,-2.009434665,1.203319712,1.354291673,,,,,,,,,-5.636547088623047,-5.238883972167969,-5.018189907073975,-5.058014392852783,-5.787701606750488 -64,64,T27K,-0.012258317,0.09458871699999999,0.071384172,-0.694698492,-1.4278894359999998,0.031149431,-0.019092941999999998,-0.005423691,-0.036900614,0.072726807,0.116450626,0.107292716,0.035475627999999995,-0.37558086799999996,-1.0138161159999999,-1.089159826,-1.766619046,1.957469488,1.817070819,,,,,,,,,-6.569981575012207,-5.688941955566406,-5.02138090133667,-5.646462917327881,-5.591264724731445 -65,65,T27M,0.023298222,-0.035811291,-0.049022294,-0.077604075,-1.84309581,-0.029550233999999998,0.010939986,0.035656457999999995,-0.091258277,-0.10585133099999999,0.03422875,-0.057910141,-0.040134447000000004,-0.117289611,-0.037918539,-1.7138987630000002,-1.9722928569999998,1.091363095,1.3386923579999999,,,,,,,,,-4.994630336761475,-4.0904340744018555,-4.627359867095947,-3.9129624366760254,-4.676270484924316 -66,66,T27L,-0.00520012,0.020403634,0.020395353999999997,-0.002497664,-0.7655211470000001,0.0071649190000000005,-0.008171017,-0.0022292220000000003,-0.034990466,0.015732065,0.025075202,0.052401689,-0.011610981999999999,0.010565294,-0.015560621,-0.5231183420000001,-1.007923952,0.64180557,1.41243685,,,,,,,,,-2.508852005004883,-0.7420024871826172,-1.6268577575683594,-0.884356677532196,-1.6240196228027344 -67,67,T27N,-0.018373965,0.05123653400000001,0.07067300900000001,-0.5670000470000001,-2.4857249219999997,-0.00692772,-0.004454341,-0.032293589,-0.000322741,0.025715797000000002,0.076757271,0.09308630300000001,0.048259715,-0.24550338600000002,-0.888496708,-2.154058947,-2.8173908969999997,1.21450464,1.303342199,,,,,,,,,-5.1588664054870605,-4.330633163452148,-4.542758941650391,-4.354796886444092,-5.001410484313965 -68,68,T27Q,-0.019357507,0.038441852,0.021874675,-0.011546786000000002,-1.6670994369999999,0.007096191999999999,-0.0037087709999999996,-0.035006243,-0.03898183,0.021153712999999998,0.055729991,0.0038834570000000003,0.039865892,0.012561832,-0.035655404,-1.7720804819999998,-1.562118392,0.638912085,1.305582282,,,,,,,,,-5.387251377105713,-4.352775573730469,-4.599409103393555,-4.388710975646973,-4.879022598266602 -69,69,T27P,-0.012825537,0.040221632,0.03461181,-0.063710394,-1.7901721609999999,0.000370384,-0.0092243,-0.016426773999999998,-0.061390324,0.033592459,0.046850804,0.050711808,0.018511812,-0.05115901,-0.076261777,-1.6082035559999999,-1.9721407659999999,0.8302584340000001,1.32360325,,,,,,,,,-5.105696201324463,-3.8134372234344482,-3.4054582118988037,-3.9122419357299805,-3.5753493309020996 -70,70,T27S,0.000828692,0.032511543999999996,0.037237365,0.00384456,-1.3924781480000001,-0.017822742,0.000763483,0.0008939,-0.133810627,-0.0009215369999999999,0.065944625,0.065397336,0.009077393000000001,0.047014477,-0.039325358,-1.0451304259999998,-1.73982587,0.7050011959999999,1.3516310390000001,,,,,,,,,-4.1269402503967285,-3.9160897731781006,-3.8231613636016846,-3.950188636779785,-4.199071884155273 -71,71,T27R,-0.040271839,0.013151862,0.052985915,-1.400772418,-2.375093809,0.008316061999999999,-0.013639617,-0.06690406,-0.077932789,-0.008145178000000001,0.034448901000000004,0.052096931,0.053874898,-0.994384024,-1.807160811,-2.093313864,-2.6568737540000003,2.059162141,1.438641087,,,,,,,,,-6.360147476196289,-5.024960517883301,-4.808837890625,-5.291454315185547,-5.385777950286865 -72,72,T27W,-0.079957782,-0.061488913,-1.224764296,-2.259024869,-2.841700815,-0.050100115,-0.069489008,-0.09042655599999999,-0.176269066,0.021794295,-0.14477212,-0.999039171,-1.45048942,-1.557633469,-2.9604162689999995,-2.748333681,-2.9350679489999996,2.414287908,1.200072427,,,,,,,,,-4.967447757720947,-4.277865409851074,-4.333554267883301,-4.094961643218994,-4.7113261222839355 -73,73,T27V,0.017138814,0.054112503,0.024078477,0.023495206,0.034189274,0.026123253,-0.013076521,0.047354148,-0.09869385,0.051003292,0.057221713,0.05185309999999999,-0.003696146,0.04636486,0.0006255519999999999,0.068248893,0.000129655,1.000995395,2.750605849,,,,,,,,,-4.235107421875,-3.35068678855896,-3.3760557174682617,-3.0817294120788574,-3.421661376953125 -74,74,T27Y,0.05417784900000001,-0.003139565,-1.082915309,-2.411546054,-2.7891347680000003,-0.043960803,0.06320822,0.045147478,-0.1212215,0.014089733,-0.020368863,-0.882236272,-1.2835943459999999,-1.795487707,-3.027604401,-2.576013455,-3.00225608,2.330971542,1.093527199,,,,,,,,,-5.4706926345825195,-4.639949798583984,-4.97636079788208,-4.521201133728027,-5.273491382598877 -75,75,L28A,-0.019704668999999998,0.035900647,-0.003939622,0.027649035,-0.20222814,0.008399527,-0.008430686,-0.030978651,0.052565441,0.0017858000000000001,0.070015493,-0.022677388,0.014798145,0.040500106,0.014797963999999999,-0.173805337,-0.230650943,1.412477244,2.1439149769999997,,,,,,,,,-3.4709653854370117,-3.5343120098114014,-3.735635995864868,-3.727619171142578,-4.080064296722412 -76,76,L28C,-0.032813414,-0.04765922400000001,-0.024893669,0.019473818,-1.95959115,0.033836026,-0.009628844000000001,-0.055997983,-0.03776968,-0.08166427799999999,-0.013654168999999999,-0.050404055,0.000616718,0.012688293,0.026259342,-1.363123509,-2.556058791,0.5280298170000001,1.317636037,,,,,,,,,-7.837523460388184,-8.149982452392578,-7.852636337280273,-9.152901649475098,-8.427891731262207 -77,77,L28E,-0.053680802,-0.027822315,0.005018305,0.034194381,-1.721637749,0.062170051,-0.060300458,-0.047061146,0.011197743000000001,-0.039050066,-0.016594563,-0.039229596,0.04926620599999999,0.029358607000000002,0.039030155,-1.548735466,-1.894540031,0.5975315179999999,1.313976786,,,,,,,,,-4.256972789764404,-4.911038875579834,-5.8396687507629395,-5.46544885635376,-5.33878231048584 -78,78,L28D,-0.038487142,0.034237114,0.001944002,-1.5040970790000001,-2.71076857,0.048642849,-0.026580588,-0.050393695999999995,0.018490153999999998,-0.004092048,0.072566276,-0.002845629,0.006733633,-1.1970689890000001,-1.811125169,-2.558354537,-2.8631826030000003,0.8629072879999999,0.747605855,,,,,,,,,-4.829272747039795,-5.037059783935547,-6.0855021476745605,-6.127694129943848,-5.878392219543457 -79,79,L28G,-0.022334179,-0.03150269,0.003770012,0.03978715,-1.484204085,0.020863209,-0.011678121999999999,-0.032990235,0.053555499000000006,-0.023316037999999997,-0.039689341,-0.035205275,0.042745299,0.012310173999999998,0.067264126,-1.400435145,-1.567973024,0.669484861,1.324566055,,,,,,,,,-5.836078643798828,-5.420743465423584,-5.226015090942383,-5.960085868835449,-5.900911331176758 -80,80,L28F,-0.040002993,-0.070440371,-0.037635603,0.015112183000000001,-0.720047067,-0.038578852999999996,-0.027566088,-0.052439897,0.013702084,-0.041360041,-0.0995207,-0.125446168,0.050174962000000004,-0.019745599,0.049969965,-0.554762104,-0.88533203,1.302795467,1.682510683,,,,,,,,,-5.825944900512695,-4.859673023223877,-5.451895236968994,-5.559168815612793,-4.948470115661621 -81,81,L28I,0.048150385999999996,-0.022671011,-0.003042581,-0.00309151,0.017395788,-0.025860834,0.088786579,0.007514191999999999,-0.05013022,-0.025007758999999997,-0.020334262,-0.05534956,0.049264399,-0.015137646000000001,0.008954627,0.027656387,0.007135189,1.2003354529999999,2.680567088,,,,,,,,,-4.049657344818115,-3.7499613761901855,-4.289217948913574,-4.472228050231934,-4.209133625030518 -82,82,L28H,-0.008017467,0.032561265,0.047690945,0.070178796,-0.889277008,-0.008464177,0.01538669,-0.031421622999999996,0.119941152,0.042575509000000004,0.022547021,0.045516028,0.049865861,0.081971662,0.05838593,-0.585200101,-1.193353914,0.39779746200000005,1.3603801469999999,,,,,,,,,-5.899195671081543,-5.485027313232422,-6.2072672843933105,-5.945731163024902,-6.035440444946289 -83,83,L28K,-0.005539491,-0.002878644,0.028632087999999997,0.059325622,0.069595673,0.10400271,-0.014369258999999999,0.0032902779999999998,-0.052811494,-0.033428372000000005,0.027671084,0.034333273,0.022930902000000003,0.059881153,0.058770090999999997,0.04615663,0.09303471599999999,1.154452356,2.8282529160000003,,,,,,,,,-4.683936595916748,-5.100150108337402,-5.4059882164001465,-5.376287460327148,-5.718339920043945 -84,84,L28M,-0.041787101,-0.049764660999999995,0.002258615,-0.00526688,-0.04806969999999999,0.025590638,-0.035141813,-0.048432389000000006,0.11083494599999999,-0.008616484,-0.09091283800000001,-0.008083692,0.012600921000000001,-0.027921638999999998,0.017387879,-0.033204382000000005,-0.062935017,1.214121872,2.476624221,,,,,,,,,-5.830758571624756,-5.8864336013793945,-5.88660192489624,-5.812458038330078,-5.581367492675781 -85,85,L28N,-0.035726656,0.023491101,0.015489448000000001,0.05982907,-1.4207135380000002,0.032766647999999995,-0.032235555,-0.039217756,-0.083636957,0.027469676000000002,0.019512526000000002,0.026470652,0.0045082429999999995,0.053052552999999995,0.06660558700000001,-1.120972321,-1.720454755,0.648017497,1.341582467,,,,,,,,,-5.450833797454834,-4.700526237487793,-5.7440290451049805,-5.762775421142578,-5.766567707061768 -86,86,L28Q,-0.056036688,0.007080485,-0.0020201010000000003,0.045650558,-0.222811812,0.034851675,-0.055223318,-0.056850057999999995,0.007987811,0.043285528,-0.029124558,-0.006053269,0.0020130670000000003,0.04749584,0.043805275,-0.16291523800000002,-0.282708385,1.299823672,2.151609564,,,,,,,,,-3.993955135345459,-4.263943672180176,-5.195327281951904,-4.237441062927246,-4.690360069274902 -87,87,L28P,-0.007785696999999999,0.004923397,-0.015633364,-0.897614543,-2.195354681,0.002928139,0.007419172,-0.022990565,0.046125877,-0.041566146,0.051412939000000005,-0.071990234,0.040723506,-0.482904325,-1.31232476,-2.039768688,-2.350940673,1.6487854240000002,1.3762643680000002,,,,,,,,,-5.530263900756836,-4.233022689819336,-5.538140773773193,-5.339469909667969,-5.479836463928223 -88,88,L28S,-0.030663797000000003,-0.019146217,-0.035706727,-0.007251026999999999,-1.264096226,0.024712166,-0.02469844,-0.036629154,0.057383265,-0.054752904000000005,0.01646047,-0.083555676,0.012142222,-0.04799515099999999,0.033493098,-1.073604209,-1.4545882430000001,0.973728461,1.391577557,,,,,,,,,-4.176138401031494,-3.4718048572540283,-3.991159677505493,-4.601019859313965,-4.2318010330200195 -89,89,L28R,-0.01000016,-0.012317896000000002,0.000608244,0.011852271000000001,-0.064935717,-0.002833226,-0.011642725,-0.008357594,0.016334951,-0.017567512,-0.00706828,-0.021453702999999998,0.022670191,0.008084394,0.015620147,-0.063067001,-0.066804433,1.236790042,2.2838463780000002,,,,,,,,,-4.76495361328125,-4.811360836029053,-5.018006801605225,-4.645031929016113,-5.092785835266113 -90,90,L28T,-0.001606327,0.014496056,0.001228926,0.003866305,-0.31365641899999996,-0.009803708000000001,-0.009859284,0.00664663,0.048529660999999995,-0.0022474179999999997,0.031239529,-0.021174838999999997,0.023632691,-0.006817963000000001,0.014550572,-0.24660265399999998,-0.380710184,1.4312701490000002,2.048091072,,,,,,,,,-4.089460849761963,-3.7003886699676514,-4.115459442138672,-4.4912543296813965,-4.440052032470703 -91,91,L28W,-0.024043175,-0.053305583,-0.024093091,-0.005568071999999999,-0.29973849399999997,-0.053695544000000005,0.000671163,-0.048757512999999995,0.115608145,-0.108664755,0.0020535889999999998,-0.103328715,0.05514253400000001,-0.071816898,0.060680754,-0.276355435,-0.323121552,1.739425948,2.24294914,,,,,,,,,-7.293686389923096,-7.611833572387695,-6.33297872543335,-7.331654071807861,-6.065136432647705 -92,92,L28V,-0.011099186,0.005321875,-0.010107739000000001,0.033466368999999996,0.0502655,0.00649983,-0.027822718,0.005624346999999999,0.113093607,-0.017248663,0.027892412000000002,-0.037449251,0.017233773,0.011705326,0.055227411,0.070190045,0.030340954,1.179595765,2.85762827,,,,,,,,,-4.33434534072876,-4.117332458496094,-4.562785625457764,-4.778909206390381,-4.930984973907471 -93,93,L28Y,-0.013498753,0.02340398,0.037875386000000004,0.049471904000000004,-0.218600359,0.053112228,0.025243257999999998,-0.052240762999999996,-0.004014579,0.024484456,0.022323502999999998,0.0017056579999999999,0.07404511400000001,0.075707921,0.023235887,-0.14341694800000002,-0.29378377,1.260382411,2.154641454,,,,,,,,,-6.95468807220459,-6.107462406158447,-6.688293933868408,-6.729149341583252,-6.171826362609863 -94,94,V29A,0.03161015,-0.001833615,0.053258459,0.056550645,0.046784507999999995,0.023513221,0.019564078000000002,0.043656220999999995,-0.005949811,-0.006176664,0.002509434,0.050462148,0.056054769000000004,0.0012183889999999998,0.11188290099999999,0.067174145,0.026394871,1.0938907420000001,2.7654161110000004,,,,,,,,,-0.9244880676269531,-1.303009033203125,-1.4712088108062744,-0.8667118549346924,-1.31841242313385 -95,95,V29C,0.051793600999999995,0.056978617999999995,0.09845768099999999,0.10055774199999999,0.035059494,0.020501593000000002,0.06513113599999999,0.038456065,0.062122526,0.033926363,0.080030872,0.036764281,0.16015108,0.085099194,0.11601628900000001,-0.001241264,0.071360251,1.147656284,2.672187365,,,,,,,,,-7.026296615600586,-6.198752403259277,-7.17348575592041,-7.663440704345703,-7.889281749725342 -96,96,V29E,-0.076401493,-0.004996111,0.00256741,0.06816767,0.05100108,-0.006401378,-0.076764329,-0.076038656,-0.052261460999999995,0.077038756,-0.087030977,0.051682473,-0.046547653,0.07970068799999999,0.056634652,0.162227967,-0.060225808,1.0972676270000001,3.14722183,,,,,,,,,-2.067516326904297,-1.8783936500549316,-2.6741480827331543,-2.0873961448669434,-2.045459747314453 -97,97,V29D,0.123781935,0.020589661000000002,0.051152647999999995,0.070239921,0.04441326599999999,-0.019608718,0.082869227,0.164694643,-0.005051826,-0.030161045,0.071340367,-0.008918065,0.11122336,-0.06335455400000001,0.203834396,0.06671392400000001,0.022112608,1.068447199,2.7368904589999996,,,,,,,,,-2.6596484184265137,-2.061087131500244,-3.3452234268188477,-2.924588918685913,-2.430537700653076 -98,98,V29G,-0.000823415,0.013215538,0.033055424,0.040087412,0.040152735,0.013481811000000002,-0.009105045,0.007458215,-0.020173158,0.017056911,0.009374165,0.037141808,0.02896904,-0.005990934,0.08616575800000001,0.053927577000000004,0.026377893,1.076833718,2.62284945,,,,,,,,,-3.863417148590088,-3.6112263202667236,-3.8320722579956055,-3.2217857837677,-3.5580906867980957 -99,99,V29F,0.052479280999999996,0.01863507,0.06402548400000001,0.103727905,-0.060232139000000004,-0.021254013,0.048621732,0.05633683,-0.041556477,-0.021618786,0.058888925999999994,0.045415392,0.082635575,-0.015414473,0.222870283,-0.050873122,-0.069591156,1.236356625,2.385207366,,,,,,,,,-5.447889804840088,-4.8939008712768555,-5.111698150634766,-5.760442733764648,-5.4620680809021 -100,100,V29I,-0.050772924000000004,0.02059818,-0.036868409,0.06271859099999999,-0.013303233999999999,-0.072786189,-0.048780545,-0.052765302,-0.062777579,-0.004606941,0.0458033,-0.040687088999999996,-0.033049729,-0.006910895,0.13234807699999998,-0.0056038780000000005,-0.02100259,1.250835485,2.6210542169999997,,,,,,,,,-3.5458927154541016,-3.146857976913452,-3.6527633666992188,-3.825274705886841,-3.6284947395324707 -101,101,V29H,-0.014345746999999999,0.024843938,0.046788515999999995,0.017439621000000002,-0.014840417,-0.036869974,-0.039654776,0.010963282,-0.034660366,0.036259942999999996,0.013427932,0.032056213,0.061520819000000004,-0.007805357,0.042684599000000004,0.00354753,-0.033228363999999996,1.148125972,2.50576595,,,,,,,,,-3.994147777557373,-3.2095940113067627,-3.6682872772216797,-4.180071830749512,-4.308809757232666 -102,102,V29K,-0.015901929,-0.021431138,0.034864865,0.030639455,0.036194098,-0.053390969,0.017719448,-0.049523305,-0.073212986,0.093542145,-0.136404421,0.063909753,0.005819976,0.054965492000000005,0.006313416999999999,0.09821175800000001,-0.025823562999999997,1.6804900280000001,3.618873133,,,,,,,,,-1.709817886352539,-0.9015817642211914,-1.3066701889038086,-1.35532808303833,-1.7275301218032837 -103,103,V29M,0.17816574,0.054498452,0.12375289199999999,0.18286428300000002,0.096017091,-0.101066501,0.20472521,0.15160626900000002,-0.062985326,0.048314605,0.060682299,0.02413368,0.223372104,0.06719994900000001,0.298528616,0.07798648700000001,0.114047695,1.0624351159999998,2.89406119,,,,,,,,,-4.659040927886963,-4.786145210266113,-5.247949600219727,-4.904539108276367,-4.978074073791504 -104,104,V29L,-0.000693695,0.011406346000000001,0.031761116,0.039559515,-0.01214075,-0.044949337,0.006982885,-0.008370274,-0.0072729990000000005,0.026452778,-0.003640087,0.060232925,0.003289307,0.011039334,0.068079695,0.025135912000000003,-0.049417410999999994,1.299873983,2.842602897,,,,,,,,,-2.998119831085205,-2.7389109134674072,-2.6337857246398926,-2.930537462234497,-3.323119640350342 -105,105,V29N,0.027439061,-0.027357327,0.014343378,0.065510499,0.051505842999999996,-0.12226369599999999,-0.024110671,0.078988792,-0.003789621,0.022812258999999998,-0.077526913,0.003826408,0.024860347,-0.003942495,0.13496349300000002,0.003093174,0.099918511,1.351575961,2.679081423,,,,,,,,,-2.5769708156585693,-1.603942632675171,-2.8964059352874756,-2.5596704483032227,-2.673126697540283 -106,106,V29Q,-0.02712337,0.006014605,0.042593005,0.026620047,0.021601685,-0.071417555,-0.04498626,-0.009260479,-0.072969547,0.008806063000000001,0.003223147,0.072550667,0.012635343,0.022296376,0.030943717000000003,0.021949461,0.021253908,1.14065731,2.699438039,,,,,,,,,-1.1219916343688965,-0.3182053565979004,-0.309722900390625,-0.41929149627685547,-0.8016791343688965 -107,107,V29P,-0.005682703000000001,0.006407446999999999,0.043631888,-1.3160347559999999,-2.3870484,-0.04179938,0.001345294,-0.012710700000000002,-0.039839861000000004,-0.00096412,0.013779014,0.042776875,0.044486900999999995,-0.872145464,-1.759924048,-2.311736352,-2.462360447,1.8679942840000001,1.312881145,,,,,,,,,-4.0116777420043945,-2.954831838607788,-3.4867124557495117,-3.8735716342926025,-2.677835464477539 -108,108,V29S,0.008664827,0.035151562000000004,0.061598774,0.07835551,0.008377766,-0.04583351099999999,-0.019010396000000002,0.036340049,-0.043936072,0.035392973,0.034910151,0.076166795,0.047030752,0.049495354000000005,0.107215666,0.033026829,-0.016271297,1.239467195,2.880565512,,,,,,,,,-2.04510498046875,-1.2728378772735596,-2.217806339263916,-1.8646957874298096,-1.889882206916809 -109,109,V29R,0.007714585,-0.00501381,0.023897913,0.041116586000000004,0.065185473,0.070105522,-0.00035861599999999997,0.015787786,-0.049437077,-0.014894056000000001,0.004866436,0.011441043,0.036354782,-0.012543148999999998,0.09477632,0.066319154,0.064051791,1.097271519,2.8484196219999998,,,,,,,,,-2.6006319522857666,-2.1363277435302734,-2.073089838027954,-2.10685133934021,-3.1848602294921875 -110,110,V29T,0.021507369,0.05291894,0.040859774,0.05519914099999999,0.029703032999999997,-0.051098656,-0.011330593,0.05434533,-0.08968191199999999,0.041579133,0.06425874599999999,0.076970068,0.004749479,0.030212668999999998,0.080185612,0.059472965,-6.69e-05,1.57943243,3.5686812480000003,,,,,,,,,-2.0884997844696045,-1.546187162399292,-2.547308921813965,-2.2340381145477295,-2.23262882232666 -111,111,V29W,0.078299356,0.010157491,0.059404704,0.038858458,0.056414715,0.051696306,0.076785755,0.07981295599999999,-0.193038778,-0.02650755,0.046822532,0.03300026,0.08580914699999999,-0.044092725,0.12180964,0.039520486,0.073308943,1.182111691,2.640051708,,,,,,,,,-6.9907121658325195,-7.640475273132324,-6.64881706237793,-7.705016136169434,-7.075530529022217 -112,112,V29Y,0.013139012,-0.052346870999999996,0.060791209000000006,0.07316557900000001,-0.087401776,-0.092002091,-0.005883819,0.032161842999999996,0.032545243,-0.05719558,-0.047498161,0.035042749,0.08653966800000001,0.020811216,0.125519941,-0.051187616,-0.123615936,1.239348798,2.5122110980000003,,,,,,,,,-6.00733757019043,-5.4967803955078125,-5.82789421081543,-6.755350112915039,-6.401490211486816 -113,113,K30A,0.098663776,0.0018760839999999999,0.021097675,0.007989488000000001,0.0005815680000000001,-0.111935875,0.108051275,0.08927627699999999,0.125844321,0.009095029000000001,-0.005342861,-0.054948823,0.09714417199999999,-0.031863578,0.047842554,0.026443097999999998,-0.025279963,1.215440898,2.643618685,0.8379057790000001,0.6285286179999999,1.042039902,1.4987585069999998,-0.29369117,1.3138930359999998,0.9132755140000001,0.075666693,-1.3421080112457275,-2.455493450164795,-2.4691948890686035,-2.6322574615478516,-2.0863399505615234 -114,114,K30C,0.033087663999999996,-0.010271905999999999,-0.019295232,-0.00294336,-1.5803495419999998,-0.046436457,0.074102922,-0.007927595,0.150253112,0.040484572999999996,-0.061028385,-0.03066882,-0.007921644,0.009360302,-0.015247021999999999,-1.3015970829999999,-1.859102,0.854706944,1.348014256,-5.779736073,-5.479257507000001,-4.939407799,-6.313172951,-6.8109703370000005,-5.3558717730000005,-6.583297117000001,-8.337572182999999,-6.327579498291016,-7.340431213378906,-7.693517208099365,-8.811042785644531,-7.673714637756348 -115,115,K30E,0.0074243569999999995,-0.015315282,-0.036557396,-0.330340993,-1.653192955,-0.136973904,0.0111703,0.003678414,0.019338955,0.007837029,-0.038467593,-0.092635858,0.019521066,-0.16987803199999998,-0.49080395299999996,-1.450872194,-1.855513715,1.2269179829999999,1.389399291,-0.8223457959999999,-1.6970779569999999,-0.7433230820000001,-0.380125427,-1.323093552,0.031891037000000004,-1.271839753,0.317896481,-3.5796751976013184,-3.825413465499878,-4.4278788566589355,-5.107394218444824,-3.5781118869781494 -116,116,K30D,0.008336566,-0.03788243,-0.022883766,-1.3174528620000001,-2.1672425140000002,-0.121515065,0.014474141999999999,0.00219899,0.104033535,-0.015772561,-0.059992299000000006,-0.09842060400000001,0.052653072999999995,-0.766639906,-1.868265817,-2.384056039,-1.9504289890000002,1.7761049830000002,1.2814501329999999,-2.418209932,-3.253353249,-2.096512154,-2.774565056,-2.335383934,-1.6312352680000002,-1.999629703,-0.90221522,-4.195044994354248,-3.96730637550354,-4.9511942863464355,-5.484946250915527,-3.532593011856079 -117,117,K30G,0.033980705,-0.004905307,0.010699258,-0.8122872170000001,-2.15303464,-0.101360972,0.054263426,0.013697984,0.115023105,0.025310383,-0.035120997,-0.070186779,0.091585294,-0.461051681,-1.163522753,-2.047418377,-2.258650902,1.626647493,1.365891776,-3.1940967089999996,-3.447734337,-2.414639771,-3.092382713,-4.168910072,-2.84681665,-2.244031052,-2.46368263,-4.762584686279297,-4.7544097900390625,-4.478805065155029,-5.093171119689941,-4.489912033081055 -118,118,K30F,0.027638142,0.008010398,0.000119235,-0.014441951000000001,-2.087469761,-0.186184963,0.009736959,0.045539325,0.098707741,0.019713267,-0.003692472,-0.089997059,0.09023552800000001,-0.081700587,0.052816685,-2.374815382,-1.80012414,0.7992767409999999,1.255140555,-6.344206351,-6.175813385,-4.970588928,-8.025809296,-7.446648804,-5.102171341,-5.849842117000001,-6.4117066760000005,-3.1156914234161377,-5.010012149810791,-4.735787391662598,-6.518143653869629,-5.100658416748047 -119,119,K30I,0.010255164,-0.091325398,-0.035397017,-0.043075065999999995,-0.404046646,-0.103629511,0.02578875,-0.005278422,-0.0012952060000000001,0.010289788000000001,-0.192940584,-0.026168319,-0.044625715,-0.005221698,-0.08092843400000001,-0.154915453,-0.653177838,1.4097763380000001,2.211424761,-4.334541829,-4.509805832,-3.477678177,-4.5217821119999995,-5.02389769,-4.139545334,-5.178339887,-5.233728922,-2.2538084983825684,-4.178758144378662,-4.400613784790039,-5.520576000213623,-4.099002838134766 -120,120,K30H,0.068215426,0.009651037,-0.017634302,0.011489618,-0.8669305959999999,-0.12539362199999998,0.10389050699999999,0.032540345,0.14324593800000002,-0.002925575,0.022227649,-0.09891257,0.063643967,-0.040180572000000005,0.063159808,-0.612208157,-1.121653035,1.173167464,1.5704268469999998,-3.7194872739999996,-4.27606691,-2.605091286,-4.27651622,-4.635035751,-2.8047262039999996,-2.424629756,-2.585755571,-4.624717712402344,-5.0190958976745605,-4.6721343994140625,-5.552500247955322,-4.591224670410156 -121,121,K30M,0.062277793,0.023867304,0.059620796,0.034297133,-0.205193373,-0.167566206,0.077750317,0.046805268,0.053903535,0.11447330300000001,-0.066738695,0.031657772,0.08758382,0.030775956,0.037818309,-0.149276376,-0.26111037,1.159116453,2.0422286990000003,-3.2414203839999995,-3.616566727,-3.0954159160000003,-3.1765680080000003,-4.014547333,-2.304003937,-3.053468105,-3.7377399760000003,-3.5171990394592285,-5.366064071655273,-4.968344211578369,-5.978507995605469,-5.336607933044434 -122,122,K30L,0.060868552,-0.002755927,0.012091929,0.00917773,-0.30245332199999997,-0.163733151,0.070470193,0.051266911,0.097357835,0.020039192,-0.025551045,-0.032931954,0.057115810999999996,-0.037604623999999996,0.055960083,-0.24121340800000002,-0.36369323600000003,1.546319059,2.119093586,-4.155451071,-4.41808667,-3.955308891,-4.298294556,-4.726511543,-3.379053696,-3.872068358,-4.281316547,-1.5031774044036865,-3.306644916534424,-3.279259204864502,-4.20035457611084,-3.4297866821289062 -123,123,K30N,0.05454254099999999,-0.007118245,-0.039191698999999997,-0.060147347000000004,-1.532004423,-0.205663956,0.06252315,0.046561932,0.104398949,-0.042242685999999995,0.028006196,-0.176746939,0.098363542,-0.091904051,-0.028390642999999997,-1.789549186,-1.27445966,0.844026608,1.313565448,-2.32740654,-2.536827377,-1.41341291,-2.6835651019999998,-2.672767746,-2.330459564,-2.328610533,-1.929901572,-4.279317855834961,-3.9667646884918213,-4.817463397979736,-4.729301452636719,-3.857245683670044 -124,124,K30Q,0.056873917,-0.002156619,0.029907995,0.04242421,-0.09384767699999999,-0.025276082000000002,0.062291927000000004,0.051455907,0.057852549,-0.00023532599999999998,-0.004077912,-0.047559457,0.107375447,-0.046455275,0.131303694,-0.11068791300000001,-0.07700744,1.5520766000000001,2.43852726,-0.281667992,-0.7865430529999999,0.22441309399999998,-0.19232415,-1.033077347,0.37919149799999996,-0.059245162000000004,0.187540596,-2.8870320320129395,-3.0485000610351562,-3.162402629852295,-3.632326602935791,-2.9070208072662354 -125,125,K30P,0.056774197,0.011558656,-0.6451668779999999,-2.126830294,-2.525360861,-0.126639626,0.08505597599999999,0.028492417000000003,0.093745909,-0.00623241,0.029349722,-0.492631505,-0.79770225,-1.938340705,-2.315319882,-2.260975792,-2.78974593,1.632231149,0.752570757,-2.89878623,-2.0823772430000003,-2.280247513,-3.102823738,-3.8812715910000004,-3.1472110669999998,-2.5164580930000002,-2.953931396,-4.592033386230469,-3.466660499572754,-3.118525505065918,-4.966955184936523,-3.6407082080841064 -126,126,K30S,0.046516324000000005,0.021456691,0.00890171,0.0068549430000000005,-0.37863247200000005,-0.10435102199999999,0.060770968,0.032261679,0.128239908,0.072688719,-0.029775338,-0.043260302,0.061063722,-0.013390882,0.027100767999999997,-0.29357325300000003,-0.46369169,1.031033586,1.706710806,-0.555635321,-0.202871422,-0.09264872,-0.480241135,-1.748080048,-0.254335281,-0.942116066,-1.11555736,-2.803813934326172,-2.5717501640319824,-3.2915139198303223,-3.852848529815674,-2.7774455547332764 -127,127,K30R,0.03564085,0.018416099,0.02329738,0.004958871,-0.006089577,-0.101736269,0.05223952,0.019042179,0.10084288599999999,0.037430635,-0.0005984380000000001,-0.019590623999999997,0.066185383,-0.012652426999999999,0.022570167999999998,0.038253262999999996,-0.050432417,1.261967274,2.8560040439999996,-0.398836171,-0.79846949,-0.070430267,-0.513058411,-1.214217468,0.601994781,-1.365970825,0.5873929489999999,-3.362379550933838,-3.7929537296295166,-3.611143112182617,-3.4052512645721436,-3.4567456245422363 -128,128,K30T,0.074175399,0.037650626,0.049637735999999995,0.029346545,-0.041735782,-0.024353211,0.12028411900000001,0.028066677999999998,0.10111700400000001,0.055799039,0.019502211999999998,-0.038494157,0.137769628,-0.0067375609999999996,0.06543065099999999,-0.058770113,-0.02470145,1.301148956,2.37562884,1.493426451,1.920127396,1.587223045,1.783307762,0.349395699,1.827078354,0.09739306699999999,-0.8518234,-2.8283987045288086,-2.9921956062316895,-3.697417974472046,-4.461373329162598,-3.0778863430023193 -129,129,K30W,0.050561882,-0.004388008,-0.015592951,-0.84836765,-2.032560763,-0.128216571,0.076736853,0.024386911,0.100389621,0.020688283000000002,-0.029464297999999996,-0.098291905,0.067106003,-0.44987580899999996,-1.24685949,-2.311228222,-1.753893304,1.608362532,1.320402571,-6.315228481,-6.152644569,-5.020183746,-7.288060196,-7.543967766000001,-5.571286125,-6.208597162999999,-6.843326166000001,-4.247239112854004,-5.600547790527344,-5.308272361755371,-7.379997253417969,-6.636725425720215 -130,130,K30V,0.062050953,-0.029194402,-0.006741151,-0.009877641,-0.06138358,-0.096197487,0.08709329099999999,0.037008615,0.11495897599999999,0.0048822579999999996,-0.063271062,-0.053612636,0.040130334,-0.031999633,0.012244352,-0.011318385,-0.111448775,1.238995107,2.553759515,-3.035197964,-3.4481820830000003,-2.42438118,-2.959265999,-3.792495995,-2.551664566,-3.504808273,-3.835945057,-2.9962949752807617,-4.387239933013916,-4.2511210441589355,-5.198352813720703,-3.949659585952759 -131,131,K30Y,-0.032652425,-0.07024907700000001,-0.064128776,-0.10163177400000001,-2.123162699,-0.225698808,-0.01108261,-0.05422224,0.071096854,-0.03064554,-0.109852614,-0.101457641,-0.02679991,-0.096910013,-0.106353534,-1.718086295,-2.5282391019999997,0.63880243,1.3077506909999999,-5.676549431000001,-5.240430244,-4.175158318,-7.222781235,-6.810007614,-4.934369743,-4.597604732,-4.786747119,-4.645549297332764,-6.0116376876831055,-5.896585464477539,-7.292713165283203,-6.018763542175293 -132,132,V31A,-0.075996644,-0.02437406,0.000986701,-0.032705785,-1.100230314,-0.007892398,-0.08607370800000001,-0.06591958,-0.013371738999999999,-0.059693578,0.010945458,-0.015030922,0.017004323999999998,-0.043814634000000005,-0.021596935,-0.7125761490000001,-1.487884479,0.7724076590000001,1.4086576380000002,-2.5629998869999997,-2.539596916,-2.873806938,-1.16427105,-2.694993637,-3.5423308939999996,-3.0295278239999996,-2.046100846,-3.807905673980713,-3.910869598388672,-4.1020588874816895,-3.625478506088257,-5.085161209106445 -133,133,V31C,-0.065796181,-0.054665922,-0.03560006,-0.080138818,-0.095361794,0.042011734,-0.112345395,-0.019246966,0.024096819,-0.06275637099999999,-0.046575472,-0.070579737,-0.0006203830000000001,-0.083053664,-0.077223972,-0.06745872,-0.12326486699999999,1.293950139,2.2597102419999997,-7.620479198,-7.680981247,-7.131140785,-6.71985659,-8.352412467999999,-8.218004898,-4.860159266,-3.947978623,-7.966256141662598,-8.37057876586914,-7.369677543640137,-9.358488082885742,-9.10413932800293 -134,134,V31E,-0.048830646,-0.989157572,-2.3650674130000002,-3.050932108,-2.9764645589999996,-0.032285376,-0.014184621000000001,-0.08347667,0.08383328599999999,-0.677285147,-1.301029996,-2.461660864,-2.268473962,-2.873635008,-3.228229208,-2.672047362,-3.280881755,0.19891587800000002,-0.562142554,-9.085897371,-9.482632393,-9.161206879,-8.324126488,-9.184479668,-9.277041427999999,-8.241014407,-8.525554921,-7.110473155975342,-8.575307846069336,-6.9474639892578125,-9.970733642578125,-8.435084342956543 -135,135,V31D,0.032329615,-0.71383255,-1.948469096,-2.322709146,-3.1479118710000003,0.009214029,0.074801808,-0.010142578000000001,-0.03480903,-0.553759007,-0.873906093,-2.1276745630000002,-1.7692636290000001,-2.3635574480000003,-2.281860844,-3.1162123110000004,-3.179611431,1.109715007,-0.284615183,-9.560686906,-10.10386174,-9.511571793,-9.017572029,-9.527042084,-9.643386887,-8.241014407,-8.525554921,-7.609045505523682,-8.985186576843262,-7.246133804321289,-10.103755950927734,-9.157258987426758 -136,136,V31G,-0.062077347000000005,-0.01700883,-0.964319232,-2.284034961,-3.019922186,0.031486572000000004,-0.04441844,-0.07973625299999999,-0.034541572,-0.039048788,0.0050311290000000005,-0.632927667,-1.2957107970000001,-2.20009978,-2.367970141,-2.972958029,-3.066886342,1.643490778,0.647165082,-8.657687073,-9.237576248,-8.62345874,-7.8483445970000005,-8.704456032000001,-8.874599747000001,-8.241014407,-8.525554921,-7.491037368774414,-7.149738788604736,-6.406537055969238,-7.330386638641357,-8.334012985229492 -137,137,V31F,-0.044471795,-0.039700708,-0.56179174,-1.806706091,-2.8994654160000004,-0.051352928,-0.039598546,-0.049345044000000005,-0.071258394,-0.045363463,-0.034037952,-0.361957951,-0.7616255279999999,-1.773932094,-1.8394800869999999,-3.003708212,-2.79522262,1.526848631,0.7729338509999999,-7.436471581,-7.018656029,-7.112294006,-6.463050132999999,-8.95459169,-7.633766045,-3.870201435,0.400074225,-4.53952693939209,-4.489051818847656,-2.813096046447754,-4.339903831481934,-5.577417850494385 -138,138,V31I,0.044659067000000004,0.00942231,0.036875603,-0.019516789,-0.051860533,-0.06270679400000001,0.045303247000000005,0.044014885999999996,0.027440762,0.023777846000000002,-0.004933226,-0.020128488,0.093879694,-0.023977696,-0.015055882,-0.044985101,-0.058735965,1.2133435590000001,2.3989563869999997,-0.435060857,-0.123762497,-0.969246185,-0.8097898179999999,-0.50168174,0.22917595699999999,-1.5164643230000001,1.2162439170000001,-2.5504162311553955,-1.8412913084030151,-2.627774953842163,-2.6204710006713867,-2.676339864730835 -139,139,V31H,-0.103879166,-0.362949439,-2.058749347,-2.273232696,-3.3994654160000004,-0.025588131,-0.09409655199999999,-0.113661779,0.07860602400000001,-0.21155801300000002,-0.514340865,-2.2192904469999997,-1.898208246,-2.18410656,-2.362358832,-3.3047382080000003,-3.4941926239999996,0.300205071,-0.386077794,-11.02338548,-10.33589017,-11.29593047,-10.20894553,-11.56431229,-11.71184893,-8.241014407,-8.525554921,-7.7009782791137695,-7.643202304840088,-6.544030666351318,-9.280385971069336,-7.896208763122559 -140,140,V31K,-0.069959217,-1.025541657,-2.282289191,-2.2384576419999997,-2.791626345,-0.015471355,-0.056984189000000005,-0.082934244,0.020253137,-0.701422558,-1.349660755,-2.7297345539999998,-1.8348438269999998,-2.238618711,-2.238296573,-2.639091056,-2.9441616330000002,0.380747902,-0.558198513,-9.626291118,-10.31131435,-9.45243634,-8.79461573,-9.529177353,-10.04391182,-8.241014407,-8.525554921,-8.371408462524414,-8.154365539550781,-6.1837158203125,-10.099119186401367,-8.438912391662598 -141,141,V31M,-0.041561627999999996,-0.007445106,-0.019076704,-0.002869713,-1.5532654280000002,-0.044758175,-0.077024889,-0.006098366,-0.080091179,-0.038053519,0.023163307999999997,-0.041572092000000005,0.0034186840000000004,-0.021768302000000003,0.016028877,-1.3509075469999998,-1.755623308,0.803002848,1.339782133,-4.757160342,-4.471318558,-4.5173685610000005,-4.742915482,-5.079248596,-4.974950516,-3.298961354,-1.560200634,-4.5472283363342285,-4.3020758628845215,-4.033563613891602,-5.001247406005859,-5.0817975997924805 -142,142,V31L,-0.031101205,-0.036818767999999995,-0.00173694,-0.031376676,-0.08842578699999999,-0.048389108,-0.053680381,-0.008522028000000001,0.013463985,-0.027364741,-0.046272794000000006,-0.024077422,0.020603543000000002,-0.033727436,-0.029025915,-0.060220939,-0.116630635,1.240399902,2.312975351,-2.326860617,-2.352951843,-1.005902313,-2.903250206,-2.9603717960000004,-2.411826927,-1.8583076840000001,1.443182849,-2.362793445587158,-1.3171792030334473,-0.7192330956459045,-0.9398478865623474,-2.2100424766540527 -143,143,V31N,-0.07502806599999999,-0.024041029,-1.09737067,-2.345433129,-2.8590112089999997,-0.045339542000000004,-0.094956601,-0.05509953,0.016846616000000002,-0.051617024000000004,0.0035349659999999996,-0.794723453,-1.4000178859999999,-2.437146518,-2.25371974,-2.888771385,-2.8292510319999997,1.097612071,0.25527794600000003,-9.883094162,-10.60920161,-10.56843042,-9.054346039,-9.737616142,-9.445876595,-8.241014407,-8.525554921,-8.060018539428711,-7.978247165679932,-6.761486530303955,-8.878165245056152,-8.238883018493652 -144,144,V31Q,-0.059804750999999996,-0.6256500079999999,-2.061013374,-2.629836465,-3.0069139089999997,0.027160731,-0.055417799000000004,-0.064191702,0.033721492,-0.47798520299999997,-0.7733148120000001,-2.194363841,-1.927662906,-2.305307988,-2.9543649419999998,-2.7057803330000003,-3.308047484,0.487568376,-0.459309165,-9.394928345,-10.14651067,-9.274348022,-8.670092072000001,-9.271468185,-9.612222771,-8.241014407,-8.525554921,-7.07270622253418,-7.237764358520508,-6.143101215362549,-8.576053619384766,-7.4526872634887695 -145,145,V31P,-0.042273958,-0.751933821,-1.770383745,-2.196451302,-3.1373510610000004,-0.044176823,-0.0223778,-0.062170116,0.022724203999999998,-0.5592656810000001,-0.94460196,-1.8044630069999998,-1.736304482,-1.973399102,-2.419503502,-2.7418482319999997,-3.5328538889999996,3.117013314,1.265685669,-8.989638065,-9.740840667999999,-8.963133873,-8.168106186000001,-9.034269843999999,-9.041839752000001,-8.241014407,-8.525554921,-7.424509048461914,-5.658719539642334,-5.114399433135986,-7.07274866104126,-7.200658321380615 -146,146,V31S,-0.047669584,-0.008726814,-0.120025718,-1.666378845,-2.725262278,-0.046619187,-0.045684265999999994,-0.049654902,-0.034127557999999995,-0.054309917,0.03685629,-0.09015321,-0.149898225,-1.30093041,-2.0318272790000003,-2.462954743,-2.987569813,1.084960804,0.771125865,-7.989450751000001,-8.354382401,-8.490204788,-6.9095855639999995,-8.006886345,-8.186194656,-7.817359495,-6.92075765,-6.482432842254639,-6.26810359954834,-5.231177806854248,-7.385493755340576,-7.217478275299072 -147,147,V31R,-0.05958056900000001,-0.717611195,-1.875773689,-2.483971873,-3.1480649510000003,-0.008960364,-0.050560348,-0.06860078900000001,0.029255400000000004,-0.507528423,-0.927693966,-1.946623155,-1.8049242230000002,-2.160229645,-2.807714101,-3.0097945210000003,-3.28633538,1.4063231180000002,-0.058265894000000006,-9.708960872,-10.47475101,-9.511413002000001,-9.10216449,-9.478334061,-9.978141800000001,-8.241014407,-8.525554921,-7.763312816619873,-7.503201484680176,-5.151981830596924,-7.982597351074219,-7.439004421234131 -148,148,V31T,-0.045244165999999995,-0.0076924509999999995,0.002721587,-0.049525107,-1.944226231,-0.018735602,-0.036194725,-0.054293607,-0.026824569,-0.016471562,0.00108666,-0.019593700000000002,0.025036872999999998,-0.061203932999999995,-0.03784628,-1.882740085,-2.005712376,0.918187608,1.311526999,-6.2356979489999995,-6.894956497000001,-6.409180824,-5.043300819,-5.959005341,-6.872046265,-6.235958592,-4.671766847,-5.454631805419922,-4.983692169189453,-5.024737358093262,-6.708418846130371,-5.984973907470703 -149,149,V31W,-0.02646088,-0.02298481,-0.9213366009999999,-2.366458266,-2.890630995,-0.020001108,-0.01724748,-0.035674278999999996,-0.037005403,-0.007281058000000001,-0.038688562,-0.615422444,-1.227250757,-2.369819268,-2.3630972630000002,-2.821444136,-2.9598178539999997,1.1038843170000001,0.327111541,-9.187465666,-8.899790344,-8.154858109,-8.157319115,-10.84349556,-9.881865204,-4.838212225,-3.17142041,-6.4516777992248535,-6.452399253845215,-3.3620429039001465,-7.062973976135254,-6.7427778244018555 -150,150,V31Y,-0.104011732,-0.8204163390000001,-2.4710410659999997,-2.7053607680000002,-2.670483841,-0.045836410999999994,-0.08707727900000001,-0.120946185,-0.027037858999999997,-0.5163391420000001,-1.124493535,-2.373023377,-2.569058755,-2.784997521,-2.625724015,-2.7595011339999997,-2.5814665480000003,0.418124624,-0.487804811,-11.43196246,-10.05513752,-12.14379382,-10.38564597,-12.370989100000001,-12.20424586,-5.306024198999999,-3.8115719269999997,-6.70662260055542,-6.622663497924805,-5.281226634979248,-7.658377647399902,-7.370266914367676 -151,151,K32A,-0.015604663999999999,0.019891445,0.0078084090000000005,0.008947247,0.054800478,-0.002158839,-0.012115308,-0.019094019,-0.007887097,0.073827632,-0.034044742999999995,0.00126584,0.014350978,0.008419326,0.009475167,0.073109985,0.03649097,1.0628804440000001,2.728188479,-1.3216939559999998,-2.873778427,-0.325176743,-3.460142937,0.602401222,-0.551772896,-3.683966882,1.152396283,-3.83020281791687,-5.056920051574707,-4.45599889755249,-6.484626293182373,-4.2990922927856445 -152,152,K32C,-0.039695645,-0.027003285,-0.021839165,-0.000174733,-0.969015678,-0.01477086,-0.042939199000000004,-0.036452091,0.021777464,0.06820574,-0.12221231,-0.026254053,-0.017424276000000002,-0.025397414,0.025047947999999997,-0.66856635,-1.269465005,0.840692518,1.438080262,-6.083610005,-7.131878113,-5.697205795,-8.132425162999999,-4.466801422,-4.989739532,-6.369513465,-4.008096216,-7.448612213134766,-9.33371353149414,-8.064948081970215,-11.163858413696289,-8.064964294433594 -153,153,K32E,-0.066786435,0.011041277,-0.017254346,0.00038264699999999996,-0.144527081,0.022663684,-0.095066284,-0.038506585,0.03718057,0.07807411,-0.055991556,0.04693887,-0.081447561,3.7e-05,0.0007282930000000001,-0.056360560999999997,-0.23269360000000003,1.334963185,2.5473945540000003,-1.336587537,-1.480103409,-0.919144981,-2.0954459990000003,-0.887650673,-1.3005926209999998,-2.066542786,0.471515256,-5.556511402130127,-7.4253973960876465,-6.09827184677124,-9.00886344909668,-6.302010536193848 -154,154,K32D,-0.080591094,-0.022217112999999997,-0.023182696000000003,-0.07894704799999999,-2.3348927059999998,0.023070007000000003,-0.07809347,-0.08308871799999999,-0.036603018,0.044819952,-0.089254178,-0.12653599699999998,0.08017060599999999,-0.073379107,-0.08451498800000001,-1.8553533969999998,-2.814432014,0.941837523,1.3153314440000001,-2.756284123,-2.7517472919999997,-2.296906914,-4.092553085,-1.976085457,-2.664127869,-3.786602979,-0.461252834,-6.63041877746582,-8.690474510192871,-6.893217086791992,-11.038463592529297,-8.018258094787598 -155,155,K32G,-0.068605018,-0.000238825,-0.015770798,0.004542492,-0.282379712,0.0049781159999999994,-0.091306135,-0.0459039,-0.045278386,0.087542021,-0.088019671,0.015913418000000002,-0.047455013,0.027912556,-0.018827573,-0.225527198,-0.339232225,1.059827846,1.810152875,-3.628366774,-4.454512512,-3.05998925,-5.580658829,-2.302362785,-2.744310493,-3.476903979,-1.3381001959999999,-6.339042663574219,-7.374346733093262,-6.475076675415039,-8.405840873718262,-6.723489761352539 -156,156,K32F,-0.034970701,0.069830428,0.002291099,0.047763703,-0.594552833,0.040633457000000005,-0.040622757,-0.029318643999999998,0.010545084,0.128267214,0.011393641000000001,-0.011360806999999999,0.015943005,0.061628345,0.033899061,-0.464260915,-0.72484475,0.5322882529999999,1.408297057,-5.196635941,-5.838807655,-4.962921188,-6.945696899,-3.52518586,-4.7105681,-5.25442034,-2.765570382,-7.595741271972656,-8.015091896057129,-6.46321964263916,-10.102500915527344,-6.753355979919434 -157,157,K32I,-0.053923187000000004,-0.006977377,0.014303943000000001,-0.00935546,-0.017447561,0.002433742,-0.073641634,-0.034204739,-0.07640196,0.076829591,-0.090784344,-0.023575119,0.052183005,0.046972401,-0.065683321,-0.01458913,-0.020305992,1.244701655,2.497998054,-3.6626840589999996,-4.460034546,-3.2915893019999998,-5.295749451,-2.232616852,-3.033430145,-3.898592622,-2.253665501,-5.693281650543213,-5.955967426300049,-6.067743301391602,-8.712464332580566,-5.364623069763184 -158,158,K32H,-0.052013552000000005,0.009416246,-0.016035267,0.008534208,0.006558769,0.008257579000000001,-0.066639252,-0.037387851,-0.067018725,0.11406514,-0.095232649,0.009189445,-0.041259979,0.06273718,-0.045668765,0.04258707900000001,-0.029469541000000002,1.301710207,3.17062907,-3.398539857,-3.5123823780000003,-3.069107025,-4.121965744,-2.393845512,-3.895398628,-4.24838776,-1.83329151,-5.71265172958374,-6.006793975830078,-5.22763204574585,-6.75349235534668,-5.335761070251465 -159,159,K32M,0.015388873999999999,0.06540062099999999,0.003718816,0.023057327000000002,-0.0038691000000000003,0.008279769000000001,0.00998322,0.020794528,0.041552822999999996,0.104038559,0.026762682000000003,-0.014190238999999999,0.021627871,0.036970492,0.009144161,-0.027968929,0.020230729,1.213061959,2.521449409,-4.37464368,-5.088653,-4.376490677,-6.1072882,-2.676566788,-3.624219734,-4.874484142,-2.792572305,-6.719222068786621,-7.433283805847168,-6.851892471313477,-9.221107482910156,-6.481734275817871 -160,160,K32L,-0.048355687,-0.007040698000000001,-0.009700128,-0.001780173,-0.075988297,0.024515292,-0.054544410999999994,-0.042166962999999995,-0.006754505,0.046311446,-0.060392840999999996,-0.038804322999999995,0.019404067,-0.015385393999999998,0.011825048999999999,-0.062223224,-0.089753369,1.521587861,2.602421961,-3.9215794739999996,-4.823204071,-3.89752195,-5.799933281,-2.018369194,-3.0688688739999996,-4.659920044,-1.885810279,-5.528690814971924,-5.654670238494873,-5.005040645599365,-7.89158821105957,-5.060506820678711 -161,161,K32N,-0.065733575,0.006450168,0.0077322630000000005,-0.015648105,-0.19436535300000002,-0.024103531,-0.085297005,-0.046170144,-0.145618789,0.04848105900000001,-0.035580723,-0.029665632999999997,0.045130159,0.003637182,-0.034933392,-0.221200039,-0.167530667,1.436897644,2.132181688,-2.976704341,-2.984287933,-2.06628096,-4.9645049210000005,-2.252551514,-2.615896378,-4.431956099,-0.9283791659999999,-5.337212562561035,-6.35167932510376,-5.687895774841309,-8.116124153137207,-6.430108070373535 -162,162,K32Q,-0.010354301,0.092674519,0.043778557,0.0034815320000000003,0.122206575,0.012338793,-0.018077528,-0.002631073,-0.061379087,0.15707363900000001,0.028275399,0.046556586,0.041000527,0.059868973,-0.05290591,0.15267144300000002,0.09174170699999999,1.053747927,2.964747425,-0.619891478,-0.156779282,-0.599383553,-0.8340753479999999,-0.604265289,-0.904953918,-1.755941358,0.090153151,-3.771186351776123,-4.563634872436523,-4.400043487548828,-5.294558525085449,-3.805097818374634 -163,163,K32P,-0.028991613,-0.351435392,-1.809724675,-2.19368559,-2.976554563,0.001891771,-0.024130227,-0.033852999,-0.035815658,-0.086091454,-0.616779329,-1.741367005,-1.878082345,-2.124869383,-2.262501796,-2.527585878,-3.425523248,0.6933068259999999,-0.028133734,-6.657078404,-7.7328633270000005,-6.031923247999999,-8.566618767000001,-4.817249985,-6.136736694,-6.129094091,-4.504052758,-8.764866828918457,-7.784872531890869,-7.047429084777832,-10.47952651977539,-9.403294563293457 -164,164,K32S,-0.033017345,-0.018210197,-0.024197017999999997,-0.008787721,-0.17798450100000002,-0.025022237000000003,-0.053070999,-0.01296369,0.005381998000000001,0.044375092000000005,-0.080795485,-0.041040235,-0.007353801,0.0013994160000000001,-0.018974858,-0.154427826,-0.201541175,1.502444811,2.281921444,-2.1162538669999997,-2.8248339839999996,-1.070628044,-4.806527718,-0.3950298,-1.484249786,-3.140940173,-0.38099838700000005,-4.673924446105957,-5.440315246582031,-5.114818096160889,-7.2728681564331055,-5.500248908996582 -165,165,K32R,-0.031927773,-0.007760311,-0.006062351,-0.017886342,0.068602495,-0.0034593009999999997,-0.046083975,-0.017771571,-0.074888896,0.073190418,-0.08871104,-0.016200362,0.0040756609999999995,0.000206862,-0.035979545,0.08448789599999999,0.052717093,1.065808838,2.7758931689999997,-0.591184605,-0.718717857,-0.752425873,-0.440273972,0.041881699,-1.086387024,-1.8391972769999998,0.57278973,-3.328990936279297,-3.5686416625976562,-2.9176082611083984,-3.8808698654174805,-2.74918270111084 -166,166,K32T,0.0051539509999999995,0.043806982,0.009874979,0.023930992,-0.146127025,0.012004618,0.012910033999999999,-0.002602132,-0.089879385,0.08644841800000001,0.001165545,-0.003040686,0.022790644,0.032783392,0.015078591,-0.11620750699999999,-0.176046543,1.366388695,2.31651611,-2.524708043,-3.243774834,-1.709476906,-5.142050323,-0.879074562,-1.649163589,-2.791133663,-0.635363317,-4.836555004119873,-5.462602138519287,-5.661048412322998,-7.226459503173828,-5.723747253417969 -167,167,K32W,-0.11583792300000001,-0.000877116,0.03673846,0.024794748999999998,-0.24052084899999998,0.021712977,-0.06475629,-0.166919555,-0.092079997,0.085441653,-0.087195884,0.088385683,-0.014908763,0.105930876,-0.056341378,-0.15508158800000002,-0.32596011,1.139721197,2.093516731,-7.769459604,-8.513265221000001,-7.538756424,-9.038483429,-6.401240295,-7.35555265,-8.401911781,-7.454458271,-8.867843627929688,-9.926875114440918,-7.947265148162842,-11.500466346740723,-8.322115898132324 -168,168,K32V,-0.004279184,0.030147444,-0.011977426000000001,-0.005510322,-0.073791384,-0.024232961,-0.017410486,0.008852118,-0.040961781,0.084598887,-0.024303999,-0.026975887999999996,0.003021036,0.003405258,-0.014425901999999999,-0.035733414,-0.111849354,1.231212902,2.4636774359999998,-3.437167526,-4.452638763,-3.113702515,-5.106428062,-1.66657811,-2.846490181,-3.9295804530000003,-1.68344417,-5.722880840301514,-6.702673435211182,-6.264270305633545,-8.701444625854492,-5.964563369750977 -169,169,K32Y,-0.030621018,0.01379667,0.026521195,0.016163333999999998,-0.35842172,0.003269877,-0.014282456,-0.04695958,-0.000681246,0.087826791,-0.06023345099999999,-0.011059388,0.064101778,0.014659253999999998,0.017667414,-0.237644813,-0.47919862700000004,1.632950097,2.26484178,-5.756456578,-6.089122345,-5.542023712000001,-7.307602081000001,-4.295888893,-5.547645859,-5.698332763,-3.381149621,-8.095771789550781,-8.631360054016113,-7.49796199798584,-10.60037899017334,-7.299983978271484 -170,170,D33A,0.028067865,-0.04812054,-0.022572997999999997,-0.040386565,-0.0056255459999999995,0.008648798000000001,-0.016807806,0.072943535,-0.096200525,-0.12281275900000001,0.026571678999999997,-0.08438582,0.039239825,-0.050254634000000006,-0.030518496000000003,-0.008656961999999999,-0.00259413,1.070070397,2.4977076019999997,0.80247679,0.328408989,1.05194574,0.8419365390000001,0.757934311,1.032158371,-0.9246621690000001,1.147866771,-1.7622796297073364,-1.0814473628997803,-0.6045522689819336,-1.2974247932434082,-1.116316795349121 -171,171,D33C,0.008000925,-0.085715771,-0.040377672,-0.08298181,-0.143159049,0.046908974000000006,-0.02011385,0.0361157,-0.076739729,-0.11634310099999999,-0.055088440999999995,-0.066729522,-0.014025822,-0.059129575,-0.106834044,-0.103644393,-0.182673705,1.3428698609999998,2.2604550519999997,-5.647521811,-5.762804611,-5.125831451,-6.190252335,-5.782899841,-5.375820816,-6.730293744,-7.812815001000001,-8.263954162597656,-7.727401256561279,-7.780160903930664,-9.315345764160156,-8.844058990478516 -172,172,D33E,-0.030137327000000002,-0.079703765,-0.004627208,-0.06942323,-0.038181221,0.002398536,-0.039935291,-0.020339363,-0.055894417,-0.09693776400000001,-0.062469765999999996,-0.020479725,0.011225309,-0.10286251699999999,-0.035983943,-0.022735049,-0.053627392999999995,1.14559757,2.243716485,0.9121137909999999,0.39334818299999996,0.814259315,0.965996552,1.211355804,1.1756091,0.168026208,0.749457736,-2.5344207286834717,-2.5133118629455566,-2.1879048347473145,-2.3350510597229004,-2.53778076171875 -173,173,D33G,-0.033577052999999996,-0.12307061300000001,-0.056711856,-0.070387108,-0.164200601,-0.039234579,-0.083108335,0.015954229,-0.06866243400000001,-0.13273454,-0.11340668599999999,-0.088232638,-0.025191072999999998,-0.049863522,-0.090910693,-0.130331409,-0.198069792,1.503541187,2.317370164,-1.195077411,-0.7135766370000001,-0.9890693509999999,-1.489844879,-1.312773933,-1.4701222530000002,-1.849383724,-0.8085067359999999,-5.236937999725342,-4.442975997924805,-3.8066635131835938,-4.90676212310791,-4.813405990600586 -174,174,D33F,0.008737043,-0.014125427,-0.002050294,-0.065057898,-0.24443278300000001,-0.072733668,-0.036603408999999996,0.054077494000000004,-0.036864066,-0.080025947,0.051775094,-0.059205725,0.055105138,-0.029565896,-0.1005499,-0.22466540899999998,-0.264200156,1.590887955,2.182387887,-4.399182268000001,-4.395158623,-4.629882545,-4.269723618,-4.389423401,-4.311723152,-4.83881443,-3.900884128,-6.364645481109619,-6.2152509689331055,-5.520486831665039,-7.107295989990234,-6.736081123352051 -175,175,D33I,-0.003618043,-0.055324998,-0.045078097000000004,-0.041143382,-0.137432674,-0.081726703,-0.020178281,0.012942195,-0.024797579,-0.080330471,-0.030319525,-0.04826706,-0.041889132999999995,-0.007796949,-0.074489814,-0.08045174299999999,-0.194413604,1.568759957,2.584738296,-2.5700394490000003,-2.824345741,-2.016215172,-2.479498581,-2.770048676,-2.760089073,-3.5929299230000002,-2.720193299,-4.578577041625977,-3.9838027954101562,-3.632753372192383,-5.13715934753418,-4.370434284210205 -176,176,D33H,0.018694363000000002,-0.03809453,-0.00484842,-0.046429917,-0.043367243,0.0024591120000000003,-0.027099971,0.064488696,0.005070412,-0.098402151,0.022213092,-0.049485363,0.039788523,-0.05421804,-0.038641794,-0.068558274,-0.018176211,1.467867817,2.449785519,-2.114678854,-1.7144647519999998,-2.737026985,-2.686160736,-1.7428557130000002,-1.692886086,-2.452988378,-1.822084611,-5.155092716217041,-3.864121437072754,-3.606037139892578,-5.178024768829346,-4.837904930114746 -177,177,D33K,-0.017405218,-0.086614501,-0.054365791,-0.080006361,-0.046872657000000005,0.01170058,-0.051793864,0.016983428999999998,-0.114247486,-0.208207014,0.034978012999999995,-0.162018852,0.05328727,-0.044059945999999996,-0.115952776,-0.05282474,-0.040920572999999995,1.298172133,2.38351553,-0.014223093000000001,0.20845569600000002,-0.24383673100000003,-0.09459121699999999,0.43496434,-0.376107552,-0.965441355,-0.052188227999999996,-3.878791093826294,-2.523622989654541,-2.3987655639648438,-3.233765125274658,-3.415116310119629 -178,178,D33M,0.020699022,-0.060268599000000006,0.001867865,-0.047416055,-0.057818308,-0.012184759,-0.005470991999999999,0.046869035,-0.096813256,-0.12350587,0.0029686720000000003,-0.029353703999999998,0.033089433,-0.040610545,-0.05422156400000001,-0.026203677999999998,-0.089432938,1.242270519,2.479057567,-2.597623955,-2.939754272,-2.2825149380000003,-2.713197884,-2.6000198969999997,-2.452632782,-3.3876831239999996,-3.215082232,-5.772618770599365,-5.043107032775879,-4.737209320068359,-5.664794921875,-5.389249801635742 -179,179,D33L,0.017343449,-0.051276325,-0.015540176999999999,-0.041125645,-0.12325609400000001,-0.077431365,-0.027761312000000003,0.062448209000000005,-0.055784044000000005,-0.093151724,-0.009400925,-0.028822359,-0.002257994,-0.021069002000000003,-0.061182288,-0.112721032,-0.133791155,1.244755435,2.145553241,-1.289866704,-1.9227475809999999,-0.674990669,-1.326394676,-1.465317116,-1.059883476,-1.6973104980000002,-2.211875867,-4.261924743652344,-3.4634242057800293,-2.8428239822387695,-4.195805549621582,-3.669802665710449 -180,180,D33N,-0.037355486,-0.118014366,-0.06751529099999999,-0.072507328,-0.11224645300000001,-0.061005645,-0.079784918,0.005073946,-0.039393628,-0.189686372,-0.04634235900000001,-0.07651685400000001,-0.058513727,-0.077954575,-0.067060081,-0.10110668699999999,-0.123386219,1.529141047,2.441341006,-1.3271630490000002,-1.201438576,-0.6502388920000001,-2.294653351,-1.295632889,-1.19385154,-1.952631617,-1.012338527,-3.818622350692749,-2.996858596801758,-3.1385412216186523,-3.74294376373291,-3.843478202819824 -181,181,D33Q,0.007322337,0.055390603,0.074061349,-0.016990856000000002,0.091680231,0.039116912000000004,-0.024839626,0.039484299,-0.146520361,-0.08689137400000001,0.19767258,0.063983096,0.084139601,0.021165611,-0.055147322,0.061061726,0.122298735,1.114191852,2.7964486280000003,1.026545825,0.889540604,0.77407663,0.5029770889999999,1.11729982,1.848834984,0.272078556,0.317271609,-2.637014150619507,-1.5070594549179077,-1.0831218957901,-1.7459524869918823,-1.838134765625 -182,182,D33P,-0.021065625,-0.802559472,-1.926844426,-2.416858057,-2.895012627,-0.015120976000000001,-0.023574382,-0.018556868,-0.005551098000000001,-0.584493614,-1.02062533,-2.013365571,-1.84032328,-2.422145831,-2.411570283,-2.397732773,-3.392292481,1.439836923,-0.109452601,-3.7395363010000002,-2.787286354,-4.315875221000001,-4.836216408,-4.216392517,-2.541911003,-3.8689113980000003,-2.029706323,-7.259240627288818,-5.487489700317383,-4.378584861755371,-6.638461589813232,-5.381640434265137 -183,183,D33S,0.032601639,-0.037366995,-0.038649426,-0.038795675,-0.055098192000000004,-0.009941255,-0.00042185,0.065625128,-0.068625717,-0.098808423,0.024074433,-0.08732652,0.010027669,-0.041447124,-0.036144225,-0.070404881,-0.039791503,1.346617838,2.392328891,-0.10474197199999999,-0.345059525,0.861704742,-0.49730036200000005,-0.548603531,0.0055488130000000005,-1.64705669,-0.28764531600000004,-3.214527130126953,-2.49092960357666,-2.134976863861084,-3.1589694023132324,-2.8859453201293945 -184,184,D33R,-0.015938911,-0.096471692,-0.02063636,-0.060886155,-0.055448761,0.000517267,-0.044070165999999994,0.012192343999999999,-0.050759813,-0.10515092,-0.087792464,-0.051898535,0.010625816000000001,-0.036682286,-0.085090023,-0.0052160290000000005,-0.105681493,1.250163816,2.4872572490000002,-0.070885849,-0.075153809,-0.38326278700000005,-0.308354774,0.299405533,0.11293659199999999,-0.13290026800000002,0.284242443,-4.719819068908691,-2.8384647369384766,-2.7502431869506836,-3.6753602027893066,-3.980919361114502 -185,185,D33T,0.004202834,-0.038370529,-0.023354019,-0.055334612000000005,0.00270366,-0.017381901,-0.034163901,0.042569567999999995,-0.045460062,-0.086442097,0.00970104,-0.015408197,-0.03129984,-0.026593647,-0.084075576,0.00210796,0.00329936,1.266983826,2.5937999080000003,-0.505052081,-0.942996872,0.141645103,-1.081496567,-0.835024345,0.19261227399999997,-1.063348698,-0.6656722279999999,-3.2761807441711426,-2.3988804817199707,-2.038081645965576,-3.256434917449951,-2.7063684463500977 -186,186,D33W,0.030054375,-0.095488369,-0.06156313099999999,-0.06184637,-0.26217333,-0.089924785,-0.0044435609999999995,0.064552311,-0.204612899,-0.159113739,-0.031862998999999996,-0.126771517,0.003645255,-0.084082485,-0.039610255,-0.272505082,-0.251841578,1.608665191,2.153229267,-5.3816069760000005,-4.914779816,-5.428023735,-6.038625809,-5.518395729,-5.008209793,-5.618158526,-5.466240647999999,-7.54835844039917,-8.284219741821289,-6.569395065307617,-8.293129920959473,-8.09174919128418 -187,187,D33V,-0.020273513,-0.08419586400000001,-0.034279172000000004,-0.073608704,-0.080936175,-0.024357951,-0.054246657999999996,0.013699632,-0.050629135,-0.093137604,-0.07525412299999999,-0.048094925999999996,-0.020463417,-0.012392344,-0.134825063,-0.056970928,-0.104901422,1.354164364,2.434191365,-2.342069954,-2.645092911,-2.120745178,-2.367964386,-2.277355248,-2.299192047,-3.318185598,-2.5717911680000003,-4.232393264770508,-3.704671859741211,-3.209537982940674,-4.56056022644043,-3.924102783203125 -188,188,D33Y,-0.008606986,-0.08538158900000001,-0.010297231,-0.058198772999999995,-0.16099438900000002,-0.072827319,-0.060259567,0.043045595,-0.063958889,-0.12450133099999999,-0.046261845999999995,-0.039034242000000004,0.01843978,-0.029671107999999998,-0.086726438,-0.159242808,-0.162745969,1.448498494,2.2007590269999997,-4.627052341000001,-4.236046127,-5.501634796,-4.810698685,-4.362141617,-4.224740478999999,-4.6263427010000004,-3.815463189,-6.681491851806641,-6.222955226898193,-5.984575271606445,-7.286547660827637,-6.853187561035156 -189,189,A34C,-0.068932711,-0.034236007,-0.0064411369999999996,-0.034724992,-0.5213988970000001,-0.016597971,-0.07661884,-0.061246580999999994,-0.129251473,0.057239632,-0.12571164599999998,-0.014511363000000001,0.00162909,0.043383802,-0.112833785,-0.282587563,-0.760210231,0.822278583,1.613852689,-5.971443784,-5.804804459,-6.146641991,-6.23464447,-6.324600029,-5.346527968999999,-5.754721842,-2.762958867,-7.097631454467773,-6.919729232788086,-7.567530155181885,-6.894124984741211,-7.8906989097595215 -190,190,A34E,-0.0033855829999999997,0.033829253,-0.288512877,-1.7741873030000002,-2.556684305,0.152784916,0.068072765,-0.07484393,-0.074891286,-0.026620708,0.094279214,-0.127160245,-0.44986550799999997,-1.691999621,-1.8563749840000001,-2.37894574,-2.73442287,0.975032155,0.7074182309999999,-2.658605421,-1.346268784,-2.006614243,-4.087689255,-3.484255676,-2.36819915,-3.8940296,-0.61948546,-5.9402008056640625,-6.4261016845703125,-6.00172233581543,-6.577744483947754,-5.414081573486328 -191,191,A34D,0.039054992999999996,-0.060048405,-1.300400217,-2.243853935,-2.404831914,-0.009712299999999998,0.070316675,0.00779331,0.033124746000000004,-0.016749552,-0.103347257,-1.094721462,-1.5060789719999998,-2.014748866,-2.472959003,-2.303754977,-2.50590885,2.680774685,1.269176658,-6.497422841000001,-5.734475174,-5.556617942999999,-7.568806015,-7.62168367,-6.005531402999999,-5.702284668,-2.703776642,-7.034093379974365,-7.805024147033691,-6.683480262756348,-7.576172828674316,-6.421573162078857 -192,192,A34G,-0.027909528,-0.058421028,-0.020882787,0.003717636,-1.8612982530000002,0.056961999000000006,0.005028976,-0.060848031,-0.015885437,-0.03623098,-0.080611075,-0.037798817,-0.003966756,0.021835498,-0.014400226,-1.42788701,-2.294709495,0.698884994,1.32460961,-6.761407748,-6.723408401,-6.215696822999999,-7.54002906,-6.900638252,-6.427266205,-7.324677192999999,-5.597197711000001,-7.43532657623291,-7.433646202087402,-6.341914653778076,-7.405769348144531,-7.490372180938721 -193,193,A34F,0.037697192000000004,0.020944169,0.083382405,0.057913149000000004,-0.922138302,-0.11511673800000001,0.008864325,0.066530058,-0.032197439,0.009912086,0.031976251000000004,-0.01195624,0.17872105,0.00595922,0.109867078,-0.659327839,-1.184948765,0.989580751,1.486046889,-5.778544209,-6.526846657,-6.281155837999999,-6.1385877760000005,-6.269626037999999,-3.676504738,-4.0991273360000005,-1.13754861,-2.693568229675293,-2.937643527984619,-3.444343328475952,-2.293757438659668,-4.565948486328125 -194,194,A34I,-0.042221993,-0.062442994,-0.000783128,-0.010175306,-0.548549981,-0.004862668,-0.072984902,-0.011459083,0.029771617,-0.027015576,-0.09787041099999999,-0.041245616,0.039679361,-0.0075952630000000005,-0.012755348,-0.40152299700000005,-0.695576965,1.4274644619999999,1.87887019,-2.182220406,-1.5295697019999999,-2.229482826,-3.3282700039999997,-2.0194830319999997,-1.804296463,-2.0512860219999998,1.6471717909999999,-1.261101245880127,0.0038886070251464844,-1.9516215324401855,-0.29793548583984375,-2.102250814437866 -195,195,A34H,-0.003337041,-0.02819132,0.028280672000000003,-1.4922301919999998,-2.609230586,-0.0022504,0.013308898000000001,-0.01998298,-0.17627118600000002,-0.016610494,-0.039772146,0.005560821,0.051000522,-1.102792299,-1.881668085,-2.157715204,-3.060745967,2.206472218,1.462723899,-6.3864383060000005,-7.68664991,-6.508765228,-5.771848877,-7.172161995,-4.792765518,-5.44767231,-2.54575115,-5.917701244354248,-5.324812412261963,-4.80500602722168,-5.04548454284668,-6.283812999725342 -196,196,A34K,-0.077572353,-0.048104207999999996,-0.06762512400000001,-1.7756094690000002,-2.635557452,0.057446671,-0.039264024,-0.115880682,0.09734742,-0.11588714800000001,0.019678733,-0.06571938599999999,-0.069530861,-1.441379129,-2.109839809,-2.730385239,-2.540729664,1.255795985,0.783212221,-6.063076887999999,-6.174085709,-5.438094688,-6.79254538,-6.598327621,-5.312331039,-5.5562968370000005,-2.40478857,-7.243950366973877,-5.225100040435791,-4.550021171569824,-5.720745086669922,-6.512049674987793 -197,197,A34M,-0.019095921000000002,-0.032903227,0.06754402,0.033118193,0.003700525,0.09172502,-0.009891635,-0.028300206,0.059415267,-0.042361197,-0.023445256,0.025061093,0.110026946,-0.004921378,0.071157763,0.055454410999999995,-0.048053362,1.115892828,2.8013129310000005,-5.414141599,-5.639139267000001,-5.1905634769999995,-5.497856606,-6.040427658,-4.702720985,-3.615274518,-1.3898556430000002,-4.125688076019287,-2.047029972076416,-3.45133376121521,-2.51296329498291,-3.973238945007324 -198,198,A34L,-0.023000883,-0.05464354900000001,0.005779463,-0.002092054,-0.88252558,0.036740237,-0.042813322,-0.0031884440000000003,-0.040629136,-0.037388634,-0.071898463,-0.032637327,0.044196253,0.002141139,-0.006325246,-0.631842141,-1.133209018,1.045491769,1.513181738,-2.9143413239999996,-3.222324448,-2.663490814,-2.665033012,-3.135467285,-2.88539106,-2.141117532,2.291497469,-0.7307100296020508,0.610906183719635,-0.9345259070396423,0.724848747253418,-1.2161204814910889 -199,199,A34N,0.022826294,0.006889193,-0.364289176,-1.6651285,-2.37743765,-0.041997954000000004,0.034767024,0.010885563999999999,-0.00279023,-0.02831812,0.042096505,-0.28177247899999996,-0.44680587200000005,-1.4110131380000002,-1.919243861,-2.13367481,-2.621200489,2.394774782,1.485436099,-6.659808302,-6.87095829,-6.7060914689999995,-7.148018737999999,-7.024010399,-5.549962616,-6.0321157979999995,-3.6386020739999996,-6.951200008392334,-6.464975357055664,-6.177870273590088,-6.443785667419434,-6.424766540527344 -200,200,A34Q,0.008920508,0.04403544400000001,0.029474761000000002,0.048950552,-1.292157836,0.132280893,0.035596674,-0.017755659,-0.020197041000000002,0.00293975,0.085131137,-0.005089305,0.064038826,0.018027905,0.07987319799999999,-1.097371679,-1.4869439919999998,0.618720061,1.33902711,-3.467140909,-2.7840205460000003,-3.3568049319999997,-4.099045433,-4.740491272,-2.355342361,-3.270409808,-1.5921853369999999,-5.566802978515625,-4.335977077484131,-4.092696666717529,-4.496148109436035,-4.9193572998046875 -201,201,A34P,-0.01686929,-0.005024349,-0.746194557,-1.9044930880000002,-2.678125708,0.001235385,-0.00337732,-0.03036126,-0.125354424,-0.02226301,0.012214313000000001,-0.488370254,-1.004018859,-1.834834129,-1.9741520469999998,-2.7259002310000002,-2.6303511840000002,1.7072784380000001,0.801368581,-6.614716512999999,-7.02655616,-6.212445015,-6.988152252000001,-6.84356694,-6.002862198,-6.52291817,-4.304579203,-8.445684432983398,-8.557373046875,-6.951269149780273,-8.045559883117676,-9.803582191467285 -202,202,A34S,-0.002500661,0.00589873,0.016221825,0.031552192,-0.245824713,-0.0084807,-0.031467837,0.026466516000000002,0.000378651,0.018720183,-0.006922724,-0.010723483,0.043167132000000004,0.016764636,0.046339748,-0.22144451699999998,-0.270204909,1.3047667520000001,2.012985693,-2.0229628369999997,-2.1525164180000003,-2.186919075,-1.968950966,-2.114584366,-1.6918433609999999,-2.728363201,-1.90000286,-5.818452835083008,-5.115476608276367,-4.813312530517578,-5.677460670471191,-5.557677268981934 -203,203,A34R,-0.045602501,-0.034062096,-1.115838268,-1.872316469,-3.0640206869999997,0.029656189,-0.030096757999999998,-0.061108243,-0.147087824,0.0028991040000000004,-0.071023295,-0.868813697,-1.362862838,-1.838326464,-1.9063064730000001,-2.632482553,-3.49555882,2.235596009,1.005925638,-5.318845952,-5.352927704,-5.192990135,-6.04935614,-6.13889711,-3.86005867,-4.02107564,-1.234196309,-6.4047088623046875,-4.269198417663574,-3.8297722339630127,-4.080593109130859,-5.096442699432373 -204,204,A34T,-0.009567616999999999,-0.023664035,-0.011399072,0.011472821000000001,-0.410171144,0.000905863,-0.030373916,0.011238683000000001,0.053473745999999996,-0.032054077,-0.015273993000000001,-0.02837167,0.005573526,0.010913688000000001,0.012031954,-0.32196398,-0.498378308,1.301585591,1.883329033,-1.477271156,-1.6955034709999999,-1.395476639,-1.5075364690000002,-1.30777063,-1.480068573,-2.003452476,-0.997618545,-4.62990140914917,-4.056272983551025,-4.099193096160889,-4.083346366882324,-4.623692512512207 -205,205,A34W,-0.026335074,-0.051258753,-0.071276705,-0.017338299999999997,-1.029580625,0.069249331,-0.034185205,-0.018484942,0.053589173,-0.048933444000000006,-0.053584062,-0.127959315,-0.014594093999999998,-0.072415285,0.037738686,-0.836706307,-1.222454942,0.899560783,1.41538364,-4.343234914,-3.86549894,-6.750972022999999,-4.7293356630000005,-4.449731445,-1.9206364980000001,-3.4672374460000004,-2.32485185,-4.749682903289795,-3.8734936714172363,-4.035027027130127,-4.036771774291992,-5.581265926361084 -206,206,A34V,0.033568335,-0.013579021,0.032664643,-0.000632127,-0.029961704,0.045825462000000004,0.018366614,0.048770056,-0.052270977999999996,-0.021534183,-0.005623859,-0.001960592,0.067289878,-0.012851373000000001,0.011587119,-0.049626105,-0.010297302,1.128665717,2.294391512,-1.950976117,-1.27618129,-1.7640052259999999,-2.328176918,-2.58455471,-1.80196244,-1.675558266,0.506115991,-2.9319868087768555,-2.589352607727051,-3.3054842948913574,-2.367642879486084,-3.8335304260253906 -207,207,A34Y,-0.014001053000000001,0.024321005,-0.022033216,0.03149482,-1.6215608469999998,-0.062116088,-0.024909325,-0.00309278,0.017561056999999998,0.025619385,0.023022624,-0.040192781000000004,-0.00387365,0.073748482,-0.010758842,-1.342080509,-1.901041185,0.5148422020000001,1.317794607,-5.948204324,-7.88748056,-6.921452164,-5.970125244,-6.161019859,-2.8009437939999997,-3.758984041,-0.41003100000000003,-4.3584818840026855,-4.079911708831787,-3.927384614944458,-3.285724401473999,-5.088603496551514 -208,208,E35A,-0.05475229400000001,-0.014474191,0.036780184,0.054124349,-1.787649562,0.085854686,-0.004990799000000001,-0.10451378800000001,0.03151672,0.00956106,-0.038509441,0.017587936999999998,0.055972430999999996,0.06438336900000001,0.043865327999999995,-1.528966365,-2.0463327590000002,0.422109774,1.307128758,-5.929663593,-5.4212415620000005,-6.157147575,-6.011878281,-4.9157176819999995,-7.142332862999999,-4.637283244,-1.338595644,-4.974829196929932,-6.4735260009765625,-2.1938118934631348,-4.889651298522949,-6.193299293518066 -209,209,E35C,-0.077656886,-0.005266344,-0.004750114000000001,-1.25494591,-2.420916886,0.006849353000000001,-0.051633728,-0.10368004300000001,0.153330431,0.053455518,-0.063988205,0.009833696,-0.019333924,-0.7632509540000001,-1.746640865,-2.494350531,-2.347483241,0.686898425,0.775656415,-10.56504296,-10.31532274,-9.78569796,-11.55889533,-10.06498613,-11.10031265,-6.725186445,-4.162726006000001,-7.954990386962891,-12.680925369262695,-5.640896320343018,-9.608908653259277,-9.837306022644043 -210,210,E35D,-0.049983982999999996,-0.05543922,0.055266172999999995,-0.866293229,-2.1195192119999997,0.035918553,-0.011261817,-0.08870614800000001,0.007471576999999999,0.017922578999999998,-0.12880101900000002,0.03070266,0.079829685,-0.44578295100000004,-1.286803506,-2.000195937,-2.238842487,1.573737617,1.358800403,-6.456120277,-5.989195358,-6.651833022999999,-5.221567116,-6.513598357999999,-7.9044075320000005,-5.858720937999999,-3.0953084769999997,-7.484726428985596,-8.805829048156738,-7.339942455291748,-9.34347152709961,-9.413829803466797 -211,211,E35G,-0.090209224,-0.073698232,0.000316768,-0.785331535,-2.321290613,-0.01236886,-0.04330095900000001,-0.137117488,-0.007883155,0.006389911,-0.153786374,-4.55e-06,0.000638086,-0.40993374899999996,-1.16072932,-2.018537393,-2.624043832,1.543068385,1.3590117519999998,-9.159798047999999,-9.170754501000001,-8.324930481,-9.442117142,-7.633027466000001,-11.22816065,-6.877165706,-3.619510497,-6.247772216796875,-8.5534086227417,-5.902604103088379,-7.778725624084473,-8.474843978881836 -212,212,E35F,-0.11479157400000001,-0.096938715,-1.271659033,-2.53993936,-2.851699887,-0.003379612,-0.105216903,-0.124366245,-0.050112360999999994,0.052402794,-0.24628022300000002,-1.0900357459999999,-1.4532823190000002,-2.6610502940000003,-2.418828426,-2.5288270109999997,-3.174572762,0.475731045,0.083517909,-11.44289333,-9.704123276,-10.50048055,-14.35192181,-10.80749157,-11.85044943,-6.411293227000001,-2.200181798,-8.531939506530762,-10.905477523803711,-6.175342082977295,-11.480894088745117,-8.869306564331055 -213,213,E35I,-0.08064698599999999,-0.0054955130000000005,0.037291055,-1.5710226669999998,-2.9875407010000004,0.021542896000000002,-0.055351893,-0.10594207800000001,-0.075997467,0.038356534,-0.049347559000000006,0.027349852999999997,0.04723225599999999,-1.107936126,-2.0341092080000003,-2.929955352,-3.045126049,0.727102253,0.740357232,-9.349729607,-8.783774445,-8.669628281,-10.99530862,-10.3713215,-7.9286151810000005,-5.341833806,-1.557977324,-6.916421890258789,-8.094648361206055,-4.126068115234375,-8.606030464172363,-7.363188743591309 -214,214,E35H,-0.067183403,0.00048497599999999997,-0.45862226,-1.6972912080000002,-2.7722213730000003,0.038553727,-0.037947849,-0.09641895699999999,0.004969192,0.05469459,-0.053724639000000005,-0.31156148,-0.60568304,-1.661050294,-1.733532122,-2.55001631,-2.9944264360000004,1.411899901,0.775323933,-12.23343287,-11.49127119,-11.79974329,-12.67571156,-12.44503737,-12.75540096,-9.901583493,-8.1113978,-8.670797348022461,-10.935952186584473,-6.67044734954834,-11.335627555847168,-10.396611213684082 -215,215,E35K,-0.081154805,-0.035719008999999996,-0.132693364,-1.6984747519999999,-2.940703589,-0.019899121000000002,-0.034532148,-0.12777746199999998,-0.070547341,-0.015754243,-0.055683775,-0.11270146800000001,-0.15268526,-1.485478216,-1.9114712880000002,-2.871768873,-3.009638305,0.763399323,0.710039475,-7.610294916,-7.12388768,-6.81177607,-9.511837067,-7.7339231029999995,-6.8700506589999994,-6.747037864,-5.06620328,-8.56502628326416,-10.432738304138184,-5.9217047691345215,-10.793341636657715,-9.507028579711914 -216,216,E35M,-0.039232433,-0.025135941000000002,0.045301033,-0.46676646200000005,-1.946449764,0.000911017,-0.006715365,-0.0717495,0.00110931,0.0630067,-0.11327858199999999,0.040223086,0.050378979000000004,-0.210724668,-0.722808256,-1.9797780319999998,-1.913121496,1.298937011,1.33185026,-10.6843925,-10.1668725,-10.4805885,-13.3241358,-11.29235183,-8.158013862999999,-7.271198486,-3.67180166,-7.626294136047363,-10.258224487304688,-6.011225700378418,-9.295793533325195,-8.474298477172852 -217,217,E35L,-0.104493531,-0.05398975599999999,-1.025849724,-2.061794733,-2.8857524789999998,-0.020752785,-0.082659046,-0.126328015,-0.040064222999999996,0.014028477,-0.12200798800000001,-0.608822464,-1.4428769830000001,-2.047072938,-2.076516528,-2.583856436,-3.187648522,1.6938377530000002,0.732852615,-8.891727442999999,-7.988080879,-9.048277542000001,-11.11329454,-9.207010277,-7.101973976,-5.506019502999999,-1.521149934,-6.586700439453125,-8.6713285446167,-4.16408109664917,-9.017128944396973,-7.903656005859375 -218,218,E35N,-0.022779565,0.01323896,0.033090159,-1.343693211,-2.7417552030000003,-0.001021363,0.033303183,-0.078862312,-0.030973756,0.009403081,0.017074838000000002,-0.008710246999999999,0.074890565,-1.208911328,-1.478475094,-2.456899286,-3.0266111189999996,0.755756999,0.7335341259999999,-10.12875914,-9.110432457,-9.88542495,-10.73626605,-10.65611533,-10.25555692,-8.288531200000001,-5.589610701000001,-7.989302635192871,-10.852248191833496,-6.465628623962402,-10.18295669555664,-10.844581604003906 -219,219,E35Q,-0.091175329,-0.048267773,-0.015757543,0.0056874809999999994,-0.608613565,0.08717042400000001,-0.092478571,-0.08987208699999999,0.017786863,0.02622783,-0.122763375,-0.024490834,-0.007024251,0.029303091,-0.017928128999999998,-0.462320981,-0.754906148,0.832654265,1.49692326,-5.628269211,-4.975271912,-5.197906532,-6.239145912000001,-5.31126384,-6.417757858,-5.2576390360000005,-3.958922662,-5.602950096130371,-7.006779193878174,-4.1248979568481445,-7.112375259399414,-6.5187578201293945 -220,220,E35P,-0.04640759999999999,-0.874068752,-1.980774861,-2.26866403,-3.388924727,0.031209828999999998,-0.026228315,-0.066586885,0.046561017999999996,-0.606005945,-1.142131558,-1.928686029,-2.032863692,-2.216399349,-2.320928711,-3.038418575,-3.7394308780000003,1.563351876,-0.022110665,-11.60054997,-11.08789054,-11.04034538,-11.88155006,-11.2649954,-12.7279685,-8.270195519,-6.187353592999999,-10.220551490783691,-11.224639892578125,-7.089859962463379,-13.356342315673828,-12.898994445800781 -221,221,E35S,-0.041127627,0.0007524869999999999,0.042683544000000004,-0.36569859,-2.463913496,0.030181532999999997,-0.017427633999999997,-0.06482762,-0.046628539000000004,0.041250961,-0.039745987999999996,0.002342739,0.083024349,-0.22442642100000001,-0.506970758,-2.158156118,-2.769670873,1.191564991,1.301815089,-8.41293336,-8.008426086,-7.693069252000001,-9.345964583999999,-8.173151131000001,-8.844055747999999,-6.341116952999999,-3.424305725,-6.233877182006836,-9.437707901000977,-4.129607677459717,-7.449293613433838,-8.650002479553223 -222,222,E35R,-0.104567601,-0.041260662000000004,0.002856633,-1.515880974,-3.10440097,0.023840781000000002,-0.059047925,-0.150087276,0.015605385,-0.027614039,-0.054907284,0.033069712,-0.027356447000000002,-1.198855775,-1.832906172,-2.929955352,-3.278846588,0.562969525,0.717426881,-8.530944912999999,-8.687296027999999,-7.94095298,-8.636654762000001,-8.079344864,-9.310475928999999,-6.614908139,-4.829754618,-8.58268928527832,-11.436915397644043,-5.91478157043457,-10.688766479492188,-10.031246185302734 -223,223,E35T,-0.076813588,-0.026697341,-0.053754188,-1.514602217,-2.8871426660000004,0.007396326999999999,-0.044531151,-0.109096024,0.014853811000000001,0.003803928,-0.05719861,-0.050295223,-0.057213152,-1.267427468,-1.761776966,-2.265537954,-3.5087473780000002,0.873050732,0.7461894379999999,-8.29855799,-7.909556831000001,-7.356843201,-8.866647652000001,-8.376646805,-8.983095459,-6.524019922999999,-2.5839727359999998,-7.109936237335205,-7.839634895324707,-4.379227638244629,-8.057865142822266,-8.382798194885254 -224,224,E35W,-0.050557560999999994,-0.32460728699999997,-1.751070295,-2.300249029,-3.040675803,-0.008750991999999999,-0.038171669,-0.062943453,0.015368328999999998,-0.119428861,-0.529785713,-1.433940156,-2.068200434,-2.0438727709999998,-2.556625286,-2.9908307339999998,-3.090520872,0.970529305,0.078243178,-12.10494565,-11.17605563,-11.96057906,-13.83641078,-10.21706438,-13.33461838,-7.24578967,-3.9416303060000004,-10.496835708618164,-13.155780792236328,-8.048934936523438,-14.038748741149902,-11.02871322631836 -225,225,E35V,-0.112075476,-0.039967375,0.015119378000000001,-1.007319116,-2.288299032,0.063008372,-0.063553663,-0.160597288,0.029912867000000003,0.019433126999999998,-0.099367876,0.047364872999999995,-0.017126117,-0.530785369,-1.483852863,-2.041433766,-2.535164298,1.741530145,1.391816015,-8.895206174,-8.547556992,-8.08642028,-9.265197525,-9.850103485,-8.726752586,-6.490059197999999,-2.03094472,-6.734941482543945,-7.5456767082214355,-3.2555184364318848,-8.02875804901123,-6.828449249267578 -226,226,E35Y,-0.05961038900000001,-0.05128201,-1.4752130540000001,-2.348920065,-3.049756216,-0.038634016,-0.020131741,-0.09908903599999999,-0.083197172,-0.011766275,-0.090797745,-1.199219286,-1.7512068219999999,-1.9810872,-2.7167529289999997,-3.024955176,-3.0745572560000003,2.389725386,0.9733445740000001,-13.57886199,-11.93632243,-12.60367753,-16.40659492,-13.04974473,-13.89797034,-9.350226271,-7.092387598999999,-9.821386337280273,-11.027182579040527,-7.384335517883301,-12.61539077758789,-10.645930290222168 -227,227,D36A,-0.041654702,-0.083681227,0.017367946000000002,-0.009070765,-0.005953824,-0.020641471,-0.045974975,-0.037334427999999996,0.001909752,-0.050726318,-0.116636136,0.110959213,-0.076223322,0.022966929,-0.041108458,0.021411218,-0.033318865,1.2585913659999999,2.7027239410000004,1.17832645,2.025713486,0.669059891,1.932755959,1.24298114,0.021121772999999996,-2.390065486,1.1341719940000001,-1.7120285034179688,-1.4313044548034668,-0.513878583908081,-1.028195858001709,-1.2986701726913452 -228,228,D36C,0.037691899,-0.065358203,0.023380895,0.041438003,-0.09995678300000001,0.02984313,0.041440634,0.033943163,0.15811729300000002,-0.031714413,-0.099001992,0.11501967099999999,-0.068257882,0.067819744,0.015056261000000001,-0.064680243,-0.13523332300000002,1.2655056340000002,2.5041477530000003,-4.122123158,-3.54815966,-4.228758247,-4.134473396000001,-3.938155594,-4.761068893,-6.441918187000001,-4.687457341,-7.588740825653076,-7.188179016113281,-6.990845680236816,-6.552290439605713,-7.856303691864014 -229,229,D36E,0.00149874,-0.055658765,0.008684261,0.03100566,0.001811128,-0.057683422000000005,-0.005926275,0.008923755,-0.045128222999999995,-0.00697742,-0.104340109,0.063509852,-0.04614133,0.08050721400000001,-0.018495894,0.062692427,-0.059070172000000004,1.543610422,3.106887046,0.513113217,0.6949879529999999,0.327084457,0.778792824,0.7219423140000001,0.042758537,-1.8991363430000001,0.31328518899999996,-2.596649646759033,-2.8837697505950928,-1.9399399757385254,-2.875298500061035,-2.769321918487549 -230,230,D36G,-0.038281083,-0.037177628,0.007476476,0.018158538000000002,0.035435688,0.085444166,-0.056294704,-0.020267461,-0.031177672000000003,0.005444279000000001,-0.079799535,0.084869454,-0.069916502,0.054560987000000005,-0.018243911,0.055260803,0.015610573,1.19868808,2.897576494,-0.896907077,0.13469577800000002,-1.3547222209999998,-0.39862751,-0.495389908,-2.370491524,-2.70406201,-0.909365967,-4.646777629852295,-4.595929145812988,-3.568293809890747,-3.755459785461426,-4.3742194175720215 -231,231,D36F,0.006982974,-0.057743486,0.021463197000000003,0.0059324469999999995,-0.068770939,-0.06399416200000001,0.012960631,0.001005316,-0.086253935,-0.050499308,-0.064987663,0.12085578,-0.077929387,0.046410705,-0.034545811,-0.036829397,-0.10071248099999999,1.237023233,2.517427644,-4.3346790760000005,-3.6897882230000003,-4.303773758,-5.053691238,-3.774185165,-4.851956993,-6.159038138,-4.651269194,-6.975120544433594,-6.055533409118652,-5.619509696960449,-6.181572914123535,-5.865370273590088 -232,232,D36I,-0.028773653,-0.10785167699999999,-0.041614332999999996,-0.027543459,-0.06987048900000001,-0.040287771,0.004518164,-0.062065469000000005,0.071261357,-0.059895601,-0.15580775300000002,0.00957589,-0.092804556,-0.009285608,-0.045801309000000005,-0.062330925,-0.07741005299999999,1.261343793,2.338969055,-2.4186406540000003,-1.631323639,-2.629121178,-2.597061943,-1.869193184,-3.366503326,-5.043325606,-2.83251096,-4.693116664886475,-3.5281569957733154,-3.178314447402954,-4.716131687164307,-3.925382614135742 -233,233,D36H,0.007738779,-0.079741578,-0.003141004,0.009838892,-0.026165024,0.002515126,0.019838794,-0.0043612370000000004,-0.033572571,-0.08314075,-0.076342406,-0.010712438999999999,0.004430430999999999,-0.016090397,0.03576818,-0.0042884229999999995,-0.048041624000000005,1.203635836,2.578888789,-0.9961859279999999,-0.548338234,-0.64699234,-1.089374222,-0.73636763,-1.9598572159999998,-2.7291433919999997,-1.4964785809999999,-4.448696613311768,-3.9694831371307373,-2.5111453533172607,-3.008998394012451,-3.5792222023010254 -234,234,D36K,0.007690486,-0.053171709000000004,0.051823025,0.050021067999999995,-0.004920756,0.015759236,-0.016535098,0.03191607,0.111138871,0.030581339,-0.136924756,0.11771686199999999,-0.014070812,0.122077103,-0.022034968,0.066865724,-0.076707235,1.0789889559999999,2.8825418289999996,1.325151903,1.7511512830000002,0.975171875,1.549388695,1.664243568,0.685804092,-2.034953443,0.681316508,-2.808168888092041,-2.142855405807495,0.38068628311157227,-0.9274983406066895,-2.1585941314697266 -235,235,D36M,0.021369936000000003,-0.059121185,0.049166729000000006,0.06535707,0.060808625,0.048310253,0.013548257,0.029191613999999998,0.003335833,-0.016516555,-0.101725814,0.10957753699999999,-0.01124408,0.067225966,0.06348817400000001,0.094424803,0.027192446000000002,1.132529104,2.9594900689999997,-3.5235213030000003,-3.086010918,-3.51147319,-3.3447618639999996,-2.990655678,-4.684704865,-5.692881476,-3.786905558,-5.585866928100586,-5.044432640075684,-4.0508527755737305,-4.890768051147461,-4.642792224884033 -236,236,D36L,-0.033029527999999996,-0.079211604,-0.005545978000000001,-0.011029001,-0.015402454,0.019561399,-0.034586281,-0.031472774,-0.032523208,-0.0009636139999999999,-0.157459593,0.042316187000000005,-0.053408142,0.035547197,-0.057605199,0.006038258,-0.036843165,1.074439185,2.578544252,-1.7988477109999998,-1.282580879,-1.939139725,-1.752561584,-1.48772892,-2.532227448,-3.692724798,-2.23926373,-4.403848648071289,-3.262253522872925,-2.5780584812164307,-3.5752906799316406,-3.344454288482666 -237,237,D36N,-0.041940973,-0.036382781,-0.003001778,0.043017768,0.044241268,-0.030818643,-0.030130111,-0.053751835,0.029920976000000002,0.008510589,-0.08127615099999999,0.055680445999999995,-0.061684002,0.091220654,-0.005185119,0.098314052,-0.009831517,1.053550075,2.9615044530000003,0.015303883,0.191889465,-0.104647171,-0.37290496100000003,0.45298521399999997,-0.090803131,-3.164600886,-0.680816572,-3.5114216804504395,-3.392047166824341,-2.5763351917266846,-2.4132351875305176,-3.0194544792175293 -238,238,D36Q,-0.074271277,-0.165097932,-0.024394392,0.008824993,-0.016961135,-0.019975333,-0.102360732,-0.046181821,-0.054743992000000005,-0.10555912199999999,-0.224636742,0.072972902,-0.121761686,0.045708553,-0.028058567000000003,0.030947854,-0.064870123,1.145365088,2.7500961310000003,0.679118826,1.201101547,0.570516068,0.9617561570000001,0.935736923,-0.273516563,-2.095782063,0.24044781699999998,-2.0566821098327637,-1.44952392578125,-0.020908594131469727,-1.0633604526519775,-1.4442838430404663 -239,239,D36P,-0.058013956,-0.081964043,-0.018619588,-0.29335164199999997,-2.091987757,-0.047257492000000005,-0.057047676,-0.058980236,-0.065450029,-0.051290960999999996,-0.112637125,0.045483555,-0.08272273,-0.173586388,-0.413116896,-1.844374098,-2.339601416,1.113016357,1.328069427,-3.122200893,-2.461625061,-3.2967239839999998,-3.074876526,-2.626273758,-4.151505135,-5.37002159,-3.2906372860000004,-7.179071426391602,-7.020723342895508,-4.930310249328613,-7.29319953918457,-7.188714027404785 -240,240,D36S,0.002656817,-0.053904553,0.021143805,0.0112443,0.009267077,-0.037758927000000005,0.005249834,6.38e-05,-0.062645815,-0.0021358220000000003,-0.105673284,0.055568955,-0.013281345,0.045317406,-0.022828807000000003,0.019158097,-0.000623944,0.971461507,2.500686899,1.146971872,1.786855782,0.777179535,1.135468925,1.35343132,0.681923798,-1.175794936,0.23548139399999998,-2.689203977584839,-2.5280327796936035,-1.8261256217956543,-1.8983495235443115,-2.356191635131836 -241,241,D36R,-0.020563764,-0.042728804,0.029087107,0.029128777999999998,0.049957800999999996,0.007559521,-0.037904493,-0.003223034,-0.038377069,-0.012065483,-0.073392124,0.067943719,-0.009769505,0.05623505,0.002022506,0.041990319000000005,0.057925282,1.1367749120000001,2.734130997,0.48383655200000003,0.550234627,1.162935135,0.997429718,0.34003539299999996,-0.63145211,-2.3234156219999997,0.919638615,-3.629228115081787,-2.5394482612609863,0.2869844436645508,-0.6698408126831055,-2.267383575439453 -242,242,D36T,-0.016305262,-0.061606735,0.008844727,0.0032221140000000003,0.006112565,-0.045103232,-0.010731224,-0.021879298999999998,0.009255274,-0.008797199,-0.114416271,0.110882282,-0.093192828,0.045342593,-0.038898366000000004,0.030647421,-0.018422291,1.096146598,2.6734270319999998,0.259143584,0.525711655,0.12210675800000001,1.131858086,0.072347626,-0.556306206,-1.939319155,-0.429911827,-2.597601890563965,-2.460476875305176,-1.538123607635498,-2.2904229164123535,-2.123046398162842 -243,243,D36W,0.025875073,-0.039805279,0.011496518999999998,0.029774255,0.07125018799999999,0.046530532,0.047029115,0.00472103,-0.053315644,-0.029152196000000002,-0.050458362,0.041174085,-0.018181047,0.003281248,0.056267262,0.073345242,0.069155133,1.248661168,2.965849074,-4.6479565460000005,-4.1063635860000005,-4.4226959610000005,-4.963425613,-4.264058922,-5.483238647,-7.031733203,-5.35243121,-8.462930679321289,-8.663566589355469,-6.126148223876953,-6.772857189178467,-7.079043388366699 -244,244,D36V,-0.012786281000000002,-0.059101552,0.048026803,0.023246056,0.000466563,0.02584015,0.019853914,-0.045426475,-0.053874383,-0.017130443000000002,-0.10107266,0.09881822300000001,-0.002764617,0.022729257000000003,0.023762855,0.042571588,-0.041638463,1.0271103320000001,2.696673147,-1.855441956,-1.300460403,-1.916375,-1.594932251,-1.426581413,-3.03886071,-3.732458621,-2.205054778,-4.156689643859863,-3.506833791732788,-2.893381357192993,-4.177414894104004,-3.7831568717956543 -245,245,D36Y,-0.049795134000000005,-0.107311591,-0.050978622,-0.01491836,-0.165573091,-0.033762522999999996,-0.086623169,-0.012967099,0.07128306200000001,-0.064808225,-0.149814957,0.0019326979999999998,-0.103889942,0.020719816999999998,-0.050556536,-0.120447945,-0.210698236,1.362441836,2.26562992,-3.043504417,-2.388603302,-3.0869060669999997,-3.9590584719999997,-2.226702484,-3.556251762,-5.588143401,-2.9876958339999997,-7.1500244140625,-6.276369094848633,-5.091704368591309,-5.644057273864746,-5.5445942878723145 -246,246,Q37A,0.013475575,-0.034838865,-0.026500827999999997,-0.010441513000000001,0.008497056999999999,-0.020677196999999998,-0.0017371189999999999,0.028688268,0.05390994599999999,-0.046398117,-0.023279612,-0.105808289,0.052806634000000005,-0.08535313900000001,0.06447011400000001,0.0028600340000000004,0.014134078999999999,1.187417751,2.478665957,-2.198182945,-0.82109597,-3.896114616,-1.98023291,-3.4156229710000003,-0.8778482590000001,-5.030943532,0.233595649,-2.8147850036621094,-2.8958683013916016,-2.4889771938323975,-2.8284454345703125,-2.82643985748291 -247,247,Q37C,0.002095961,-0.037353162,0.054402687000000005,-0.0034443909999999998,-0.092868754,0.03202472,0.018661609,-0.014469687,0.136528183,-0.11704468300000001,0.04233836,-0.005949655999999999,0.11475503,-0.079104555,0.072215773,-0.036520699999999996,-0.149216808,1.35029261,2.442460732,-6.265946877999999,-5.166815033,-7.35081115,-6.81415303,-6.505281997999999,-5.49267318,-7.652492333,-3.8525427889999997,-7.219388008117676,-8.192501068115234,-8.242561340332031,-8.011260986328125,-8.264054298400879 -248,248,Q37E,-0.01183281,-0.029650997000000002,0.012494158,0.044003892999999995,0.004526454,0.096054512,-0.046759292,0.023093673,-0.037504503,-0.017236691000000002,-0.042065302,-0.054194488,0.07918280400000001,-0.030055734,0.11806352,0.013645661000000002,-0.004592754,1.12192323,2.597957697,-1.426059584,-0.395681175,-2.521451088,-2.095011787,-1.5999355469999998,-0.5182183229999999,-3.377207111,0.443794891,-3.454103708267212,-4.738487243652344,-4.740413188934326,-5.337688446044922,-4.016633033752441 -249,249,Q37D,-0.003060218,-0.022749737000000003,0.037064723,-0.002470336,-0.085462237,0.006734072,-0.012668745,0.00654831,0.056028815999999995,-0.019680931000000002,-0.025818543,-0.043595075,0.11772452,-0.09285454,0.087913868,-0.054366980999999995,-0.11655749300000001,1.360552195,2.329526199,-2.653641107,-1.766590149,-2.321700912,-3.832107391,-3.6569979630000002,-1.69080912,-4.439020311,0.10278575400000001,-4.307510852813721,-5.958794593811035,-5.4810590744018555,-6.133440971374512,-4.99384880065918 -250,250,Q37G,-0.009567354,-0.011964871,-0.006138523000000001,-0.016341361999999998,-0.013549446000000001,0.030613001,-0.009323831999999999,-0.009810875,0.057211557,-0.033157149,0.009227407,-0.057139692,0.044862647,-0.063992496,0.031309773,-0.018251812,-0.008847079,1.272649724,2.456592866,-3.9384470339999997,-2.809903435,-4.36294371,-4.994198204,-4.66131871,-2.8638711089999997,-5.416925494,0.105815729,-4.159162998199463,-4.640970230102539,-4.417693614959717,-4.759208679199219,-4.515362739562988 -251,251,Q37F,-0.03867964,0.014379738000000001,-0.018430252,0.008288437,-0.012968656,0.04203137,-0.017779355,-0.059579924000000006,0.07040608599999999,0.029200746,-0.00044127099999999997,-0.06532956599999999,0.028469063,-0.025370819,0.041947692,0.022214785,-0.048152096,1.15107975,2.558686959,-6.42908054,-6.090999146000001,-6.27020372,-7.059609718,-6.317036606,-6.407553513,-7.886565613999999,-4.25324109,-5.895354270935059,-7.4635443687438965,-5.77030611038208,-6.862668037414551,-6.365535736083984 -252,252,Q37I,0.015214917,-0.012544638,0.026633674,0.004254193,0.009937148,0.022014633999999998,0.013224136000000001,0.017205698000000002,0.029250407000000003,0.03375314,-0.058842415,-0.012489985,0.065757333,-0.009861515,0.0183699,0.024511292,-0.004636997,1.246358117,2.740319173,-5.1079325010000005,-4.5386735080000005,-5.3500802919999995,-5.281901314,-5.302417053,-5.06659034,-6.673518357000001,-3.5687185880000003,-4.728646755218506,-5.601255893707275,-4.816488742828369,-5.945565700531006,-5.146157264709473 -253,253,Q37H,-0.018251094,-0.059180152,0.009643872,0.006968991999999999,0.00280529,-0.044123375,-0.009581504,-0.026920682999999997,0.028903565,-0.023204638,-0.095155666,-0.017266136,0.03655388,0.005619248,0.008318736,-0.011248353,0.016858932,1.107887337,2.59724708,-3.2940336880000003,-2.674552109,-3.5502002939999997,-3.6285799639999996,-3.53234388,-3.084492195,-5.044124948,-2.1848433519999997,-5.062426567077637,-5.116504669189453,-4.503952980041504,-4.741662979125977,-4.675346374511719 -254,254,Q37K,0.015703717,-0.050748527,0.031059995,0.018645675,0.011905738,0.049587569000000005,0.00772575,0.023681683,0.091976244,-0.049679929000000005,-0.051817124000000006,-0.044590215,0.106710204,-0.029438871000000002,0.06673022099999999,-0.029438871000000002,0.053250347,1.21871546,2.42415044,-1.264592827,-0.49038530700000005,-2.390751076,-1.225363953,-1.352695297,-0.8637685009999999,-2.77053081,0.001415429,-3.2669482231140137,-2.61248779296875,-2.131817579269409,-1.9004617929458618,-1.833400011062622 -255,255,Q37M,0.022171242,-0.040002664,0.022624394,0.032960689,0.027739205,0.012116823999999998,0.0029941209999999998,0.041348362,0.023764574,-0.035455197,-0.04455013,-0.039614308,0.084863095,-0.034310764,0.100232142,0.042483059000000004,0.01299535,1.075444182,2.612986375,-5.149427977,-4.986198494,-5.539893768,-5.425359909,-5.337031158,-4.458656555,-7.091183707000001,-3.542858139,-5.368071556091309,-6.262600898742676,-5.373014450073242,-6.329164505004883,-5.575399398803711 -256,256,Q37L,0.012956829,0.015188303,0.023039825,0.034235913,0.01388525,-0.019787242,0.020760738,0.005152919000000001,0.025682656,0.018656742,0.011719863,-0.009331208,0.055410858,-0.010290697,0.078762523,0.023704531,0.004065969,1.128423399,2.636717892,-3.516231752,-4.02344722,-3.3292425160000003,-3.333450897,-3.37800827,-3.5170098569999997,-4.87426925,-2.083886688,-3.863468885421753,-4.740053653717041,-3.8236865997314453,-4.625616073608398,-4.51646614074707 -257,257,Q37N,-0.007810898,-0.017334184,0.011595097,0.0038964629999999997,0.020191115,0.018040362,-0.00288427,-0.012737526,0.005168492,-0.035902736,0.001234369,-0.056722238,0.079912432,-0.09763997599999999,0.105432901,-0.026521028,0.06690325700000001,1.3624115019999998,2.520843974,-2.824168452,-2.2954244999999998,-2.474125084,-3.895144081,-2.6539424130000002,-2.8022061839999997,-5.1432707660000005,-0.604549101,-4.584223747253418,-4.682755947113037,-4.77299690246582,-4.380924224853516,-4.251570701599121 -258,258,Q37P,0.022477996,-0.01054113,0.012721455,-1.3091965890000001,-2.202043505,-0.047024175,0.045456844,-0.000500852,-0.017297097,-0.007797084,-0.013285175,-0.027729774,0.053172684000000005,-0.9234519370000001,-1.69494124,-2.050917613,-2.3531693959999997,2.139204527,1.503376333,-5.541554872000001,-4.015758614,-6.828863564,-5.875159439,-6.272567168999999,-4.715425575,-6.365100421,-1.8899330019999998,-5.655114650726318,-6.199551105499268,-5.363576889038086,-6.8680644035339355,-6.517544746398926 -259,259,Q37S,0.011986918999999999,-0.007524843000000001,0.0025294320000000003,0.023025887000000002,0.007432733,-0.007627401,0.017127231,0.006846606999999999,0.073721199,-0.017090793,0.002041107,-0.042124164000000006,0.047183027,-0.022278521000000003,0.068330294,0.014285208999999998,0.0005802569999999999,1.203230196,2.740091345,-2.185639679,-0.899332283,-3.673700256,-2.132792892,-2.413339714,-1.809033249,-5.2105282939999995,0.008645027,-3.456233263015747,-3.441835880279541,-3.416159152984619,-3.6505420207977295,-3.0375914573669434 -260,260,Q37R,-0.021317681,-0.004005672,0.007115336,0.015062096,0.03108761,0.022157542000000002,-0.021656908,-0.020978452999999998,0.040234549,-0.005110079,-0.002901264,-0.046307854,0.060538525999999995,-0.014770083,0.044894275,0.027082115,0.035093104,1.33432194,2.864895717,-0.699679449,0.387381828,-1.437676643,-1.080140366,-1.478202469,0.11024040199999999,-2.191038873,0.629104805,-3.1598775386810303,-1.6507997512817383,-1.3088302612304688,-1.7119547128677368,-1.3020806312561035 -261,261,Q37T,0.020963225,-0.0351101,0.008072791999999999,0.010537418,-0.011476301999999999,-0.011794971999999999,0.031487932999999996,0.010438517,0.083069955,-0.054105434,-0.016114765,-0.071051344,0.087196927,-0.067702372,0.088777207,-0.004622112,-0.018330491,1.3411160359999998,2.6275328190000002,-2.229295645,-0.862056168,-4.218545348999999,-1.791866051,-2.702212692,-1.5717979659999999,-3.820195376,-0.607356605,-3.7999494075775146,-4.044106483459473,-3.636354446411133,-3.936864137649536,-3.505925416946411 -262,262,Q37W,-0.0072093190000000005,0.004655879,-0.00449747,0.017618204,-0.029962936000000003,-0.019107805,-0.023537027000000002,0.00911839,0.023515644,-0.013465428,0.022777186,-0.040018372,0.031023432000000004,-0.031029987000000002,0.066266395,-0.004012933,-0.055912939,1.2989874609999998,2.651238149,-5.941871494,-5.351138023,-6.511625777999999,-6.232775169,-6.121073639,-5.492744857999999,-7.24363798,-4.244214405,-7.3459038734436035,-8.423952102661133,-6.370109558105469,-8.56698226928711,-7.116412162780762 -263,263,Q37V,0.005571385,-0.014868846000000002,-0.008102534,-0.008003736,-0.009010772,-0.001559684,-0.02375958,0.03490235,0.030535424,-0.051932205,0.022194513,-0.057983344000000006,0.041778276,-0.076168127,0.060160655,-0.010336604000000001,-0.00768494,1.276755325,2.5206573519999997,-4.566301718,-4.351111183,-4.948481682,-4.371912758,-5.398552505,-3.761450462,-6.117442707,-2.677320645,-4.303139686584473,-5.253438472747803,-4.466437339782715,-5.152095794677734,-4.641301155090332 -264,264,Q37Y,0.032321182000000004,-0.013275173999999999,0.009741443,0.016868122,-0.050090694000000005,-0.010390251,0.015933753000000002,0.04870861,0.06277607,-0.046523644,0.019973296,-0.113911245,0.133394131,-0.076492015,0.11022825900000001,-0.025178816,-0.07500257099999999,1.4371617419999998,2.522602388,-5.651566237000001,-4.83251799,-5.976137802,-6.497289169,-5.6371358570000005,-5.314750366,-7.424068471,-3.309527611,-6.156320571899414,-7.355611324310303,-5.576890468597412,-6.891737937927246,-6.275954246520996 -265,265,L38A,-0.036084275,-0.024499052,-0.025508815,-0.032336151,-1.5811186469999998,0.097808454,-0.016201131,-0.055967418,-0.069158477,0.014315446,-0.06331355,-0.008105304,-0.042912325,-0.005063157,-0.059609144,-1.264756797,-1.897480496,0.760242283,1.339958771,-8.685752034,-7.431558624,-8.695046364,-7.080600166,-10.66182262,-9.559732391,-3.94502692,0.37195350299999996,-6.1736040115356445,-6.040172100067139,-3.9940712451934814,-5.849860191345215,-7.159923076629639 -266,266,L38C,0.032500706000000004,0.054308275999999996,0.036401874,-0.051520496,-2.132422185,0.07841328,0.073338782,-0.008337371,0.030227026,0.067964805,0.040651747,0.00962721,0.063176538,-0.05262911,-0.050411882000000005,-1.9428911619999998,-2.321953207,0.8205808529999999,1.303259792,-10.53306749,-10.61580608,-9.699528091,-11.2616125,-12.13649152,-8.951899254,-6.358900087,-2.277954587,-8.539658546447754,-8.140230178833008,-7.642336845397949,-8.890156745910645,-10.489609718322754 -267,267,L38E,0.007020666,0.053261009000000005,0.015303333999999998,0.027263698,-1.69693259,0.080244211,0.026734182999999998,-0.012692852,-0.10530061800000001,0.04805206099999999,0.058469956,-0.034849075,0.065455742,0.031571889,0.022955507000000003,-1.494596234,-1.899268945,0.7444425809999999,1.324672427,-11.38094572,-11.95427306,-10.10961348,-12.08169437,-12.03071597,-10.72843171,-6.443532824,-2.41408747,-9.84881591796875,-11.291659355163574,-8.188623428344727,-12.515626907348633,-9.896288871765137 -268,268,L38D,-0.018575298,0.030273038,0.026986523999999998,0.07572081900000001,-1.72549043,0.051976555,-0.04156863,0.004418035,-0.148596904,-0.039460178,0.100006253,-0.024509668,0.078482716,0.078367198,0.07307444,-1.573675305,-1.877305555,0.62541432,1.313824582,-11.45223208,-12.36083303,-10.19883658,-12.47675761,-11.56261189,-10.66212132,-5.705134796,-2.5023196469999998,-10.1058349609375,-10.814502716064453,-8.592843055725098,-12.492681503295898,-9.94774341583252 -269,269,L38G,0.000641591,0.016289419,-0.022557695,-0.019264259,-1.413216117,0.088820831,0.038925307,-0.037642125,-0.041049764,0.036695868,-0.004117031,0.002617341,-0.04773273,-0.029052161,-0.009476357,-1.007953808,-1.818478426,0.826863204,1.3733831509999999,-11.38058441,-10.71061833,-10.76401826,-11.52271614,-12.20099622,-11.70457311,-5.774860003,-2.00599906,-9.372525215148926,-9.897151947021484,-6.483849048614502,-9.757120132446289,-9.606106758117676 -270,270,L38F,0.009911524,-0.01435726,0.039812405,-0.041355939,-0.674853968,0.093093476,-0.00657086,0.026393907,-0.18542828,-0.020990791,-0.007723729,0.0007798130000000001,0.078844996,-0.073624862,-0.009087016,-0.436949398,-0.912758538,1.200856462,1.682244233,-6.442623038,-9.133624146,-4.64315345,-6.614286224,-5.674581047,-6.147470322,-4.481184371,0.398168927,-4.619014739990234,-5.300729751586914,-4.169660568237305,-5.518829345703125,-6.54386043548584 -271,271,L38I,0.021416114,-0.032329569,-0.031169739,-0.049498635,-0.372458419,-0.010307277,0.023948795,0.018883432,-0.207756202,-0.055727949000000006,-0.008931189,-0.050159115,-0.012180363,-0.069728123,-0.029269146,-0.29554569399999997,-0.449371144,1.4712114630000002,2.0052156709999998,-3.483750658,-3.818187271,-3.2832077639999997,-3.981381401,-3.5568825530000003,-2.7790942989999996,-3.80013138,-1.237287984,-5.225003242492676,-5.502636909484863,-4.710995674133301,-5.282916069030762,-6.638605117797852 -272,272,L38H,0.027157683,0.007122961,-0.00741479,-0.034864848,-1.263921658,0.070474713,0.034447543,0.019867822,-0.11199431900000001,0.008734496999999999,0.005511425,-0.031509125,0.016679546,-0.06598458,-0.0037451159999999997,-1.049702618,-1.478140697,0.978687832,1.3957291369999998,-10.21470181,-11.35886645,-8.569752869,-11.82796991,-10.57031552,-8.746604286,-4.116264684,-0.169269112,-8.328407287597656,-8.083991050720215,-6.567809581756592,-8.998054504394531,-8.32310676574707 -273,273,L38K,-0.077827682,0.035299117000000005,0.003382869,-0.067947336,-2.224309184,0.134057691,-0.02282425,-0.132831113,-0.20708471,0.048881282000000005,0.021716951,-0.006466384,0.013232121000000001,-0.023621074,-0.112273598,-1.823281259,-2.625337108,0.58159807,1.301765008,-10.89395408,-13.39562808,-8.650029572000001,-11.49820211,-10.24843256,-10.6774781,-5.561402256,-0.434391011,-11.369942665100098,-10.076395988464355,-8.089741706848145,-10.336701393127441,-9.766459465026855 -274,274,L38M,0.006844301999999999,-0.013503707,-0.039752019,-0.018308208,0.039525158,0.110577646,0.027613086000000002,-0.013924482,-0.125715083,-0.035207978,0.008200564,-0.04085002,-0.038654018,-0.035917984,-0.000698432,-0.040556189,0.119606504,1.450314855,2.5612840080000003,-7.186625591,-7.741253426,-6.658322807,-7.053589256,-7.343015472,-7.136946991,-6.487837799999999,-2.784617623,-6.599004745483398,-7.14100456237793,-5.907567501068115,-6.376564025878906,-7.576149940490723 -275,275,L38N,-0.021271976,0.082115635,-0.035783916,0.016296568,-1.721639345,0.043558539,-0.005108255,-0.037435697000000004,-0.115417752,0.046178734000000006,0.118052535,-0.056739645,-0.014828186,0.011706006000000001,0.02088713,-1.446386409,-1.996892281,0.739385411,1.326643906,-10.91688667,-12.83726284,-8.678019066000001,-12.49053517,-12.18524563,-8.393370628,-5.327972442,-1.71684058,-8.478660583496094,-8.216099739074707,-6.305774688720703,-9.256064414978027,-8.802331924438477 -276,276,L38Q,-0.042838182999999995,0.005543534,-0.015836337,0.028416585,-1.495932181,0.084381077,-0.049628574,-0.036047792,-0.033398221,0.03924487,-0.028157803,-0.030102768,-0.001569906,0.000670087,0.056163082,-1.598395473,-1.3934688880000001,0.615607525,1.311533522,-9.822292548,-10.91223233,-8.581262557999999,-11.12782203,-9.336752007000001,-9.153393814,-6.016036565,-1.6311621040000002,-8.752982139587402,-8.665274620056152,-6.56256628036499,-9.333013534545898,-8.262228012084961 -277,277,L38P,-0.022086388,-0.020702261,-0.037503621,-0.046259049000000003,-1.51455909,0.045366008,-0.009084821,-0.035087954,-0.111735146,-0.011554845,-0.029849676000000002,-0.049179342,-0.025827898999999998,-0.051786025,-0.040732073,-1.4183522519999998,-1.6107659269999999,0.707074608,1.327017295,-12.70543403,-14.05712273,-11.88686693,-12.43411126,-13.13324912,-12.01582009,-7.162804476,-2.6217315080000003,-10.841876983642578,-12.020980834960938,-8.803274154663086,-11.194999694824219,-9.785581588745117 -278,278,L38S,-0.025628826,0.005934258,-0.015047861000000001,-0.047805993,-0.8845963490000001,0.091171065,-0.016748463,-0.034509187999999996,-0.064305145,0.037833043999999996,-0.025964527999999997,-0.012456077,-0.017639645,-0.051836854,-0.043775130999999995,-0.656627583,-1.1125651140000001,1.111638181,1.5350994059999998,-7.654905255,-7.71889605,-6.487159119,-8.63528656,-9.574180823999999,-5.859003723,-3.237204007,0.051233415,-6.157329559326172,-6.145959377288818,-3.29164457321167,-5.658181190490723,-7.261943817138672 -279,279,L38R,-0.008876925,0.002090757,-0.021993545,-0.217223563,-2.052487335,0.053667173,0.015666904,-0.033420754,-0.104741429,0.028816124,-0.02463461,-0.057494235,0.013507145,-0.17541948300000001,-0.25902764300000003,-1.9212492369999998,-2.1837254319999997,1.326826835,1.32411559,-10.3081636,-11.06804789,-9.447527877999999,-10.83105425,-10.43445696,-9.75973101,-4.772213727,-1.7088745269999999,-10.48031997680664,-9.980578422546387,-7.738072872161865,-9.11799430847168,-9.511674880981445 -280,280,L38T,-0.006831895,0.036676415,-0.01770499,-0.027612948,-0.369701482,0.11676921800000001,0.001163389,-0.014827178,-0.133721363,0.005189216,0.068163614,-0.042459897,0.0070499180000000005,-0.037734465,-0.01749143,-0.34616000399999997,-0.393242959,1.207653389,1.7671813280000002,-7.403314152999999,-7.900249412999999,-7.485204109,-7.089641296,-10.19161333,-4.349862617,-4.490535058,-0.680221755,-5.218289852142334,-5.433687686920166,-4.073221206665039,-5.949611663818359,-6.972568511962891 -281,281,L38W,0.007240236,0.008649317,0.01615162,-0.061031971,-0.62371773,0.163826682,0.015014261000000001,-0.000533789,-0.09368677199999999,-0.008158053,0.025456687000000002,-0.013508343999999999,0.045811584,-0.105235619,-0.016828323,-0.460997393,-0.7864380670000001,1.660141949,1.997512823,-12.24511037,-13.64904004,-10.95416203,-13.3831639,-11.896614999999999,-11.34257085,-7.489689975,-4.691202126,-8.973822593688965,-9.499354362487793,-6.600720405578613,-9.373001098632812,-9.180410385131836 -282,282,L38V,-0.078594625,-0.025269512999999997,-0.050148182,-0.024244138,-1.6602376840000002,0.081376983,-0.053496515999999994,-0.10369273300000001,-0.108244041,-0.005891084,-0.044647941,-0.040916537,-0.059379826,-0.006722659000000001,-0.041765616,-1.313408125,-2.0070672430000003,0.81897376,1.340261743,-4.433360303,-3.689975327,-3.934018967,-4.921222176000001,-5.044612007,-4.576973038,-3.409149002,-0.885409642,-6.382407188415527,-6.381297588348389,-4.917501449584961,-5.999039173126221,-7.100573539733887 -283,283,L38Y,-0.020096759,0.006630871,0.026163047000000002,0.008026452,-0.342970173,0.138370292,-0.031373708,-0.00881981,-0.133750813,0.026584873,-0.013323132,0.05059633400000001,0.00172976,-0.020492756,0.036545659,-0.23793565100000003,-0.448004694,1.5088789669999998,2.143939584,-10.25337876,-13.24119003,-7.650171768,-11.66278089,-9.965408973999999,-8.747342125,-3.964063777,0.095320722,-7.457027912139893,-7.346952438354492,-5.73075532913208,-8.504035949707031,-8.206254005432129 -284,284,G39A,-0.018175581,-0.017296823,0.004159079,-0.016124848,-0.051723869000000006,0.0064381690000000005,-0.010421729,-0.025929432000000002,0.016051568999999998,-0.053339385999999996,0.01874574,-0.0020444639999999997,0.010362620999999999,-0.017374096000000002,-0.014875599,-0.075227393,-0.028220345,1.26573419,2.330842986,-2.305557086,-2.1833595580000003,-2.411863701,-1.314909004,-2.6280638730000003,-2.989589294,-2.287964036,-2.369941989,-5.720334053039551,-5.767180442810059,-5.833366394042969,-7.007076740264893,-6.231879234313965 -285,285,G39C,-0.10714680000000001,-0.125044225,-0.08729745,-0.020649595,-1.1095863209999999,0.005034329000000001,-0.098605507,-0.11568809199999999,0.066509415,-0.056326918,-0.19376153100000001,0.003578724,-0.178173623,-0.006897919000000001,-0.034401271000000004,-0.65553961,-1.5636330319999998,0.9523379059999999,1.476119502,-5.220351968,-4.784487816,-5.658764175,-4.626481644,-5.418281311,-5.613744896,-5.2358188189999995,-5.899151552,-9.252153396606445,-9.495948791503906,-10.430828094482422,-9.698135375976562,-10.730295181274414 -286,286,G39E,-0.025114555,-0.032570732000000005,0.001576919,0.020539605,-0.046368472,-0.003987683,-0.007564349000000001,-0.042664760999999995,-0.012997076000000002,-0.029316732999999998,-0.035824731,0.012801753,-0.009647915,0.011229612,0.029849597999999998,-0.013169385,-0.07956755900000001,1.238612166,2.494572306,-2.20269892,-1.9515571369999998,-2.872245552,-1.645568146,-1.419238785,-3.124884979,-3.027045757,-2.233849494,-5.43691349029541,-6.449240207672119,-6.732572078704834,-7.84738826751709,-7.212240219116211 -287,287,G39D,-0.059309297000000004,-0.038062946,0.005496867,-0.004272313,-0.041516898999999996,-0.027531486,-0.023204581000000002,-0.09541401199999999,0.018124438,-0.005584921,-0.070540971,0.02451263,-0.013518896,0.025626481,-0.034171106,-0.002435793,-0.080598004,1.267745653,2.641942283,-0.9055096309999999,-0.975800125,-0.892875961,-0.47951193200000003,-0.39023509999999995,-1.7891250380000001,-1.172135141,-0.805415896,-4.6175947189331055,-5.244462966918945,-5.99481201171875,-6.994447708129883,-5.856042861938477 -288,288,G39F,-0.086846373,-0.094038668,-0.016561159,0.042664764,-0.618090784,0.07120549400000001,-0.055588349,-0.118104396,-0.003064861,0.000366854,-0.18844418899999998,-0.00603342,-0.027088897999999997,0.074718945,0.010610583,-0.426546364,-0.8096352040000001,0.9214798470000001,1.553908355,-6.09310014,-7.246628754,-6.4078273160000006,-4.290616417,-6.033911934,-6.486516281,-6.460641067,-6.974351762,-9.60685920715332,-9.267684936523438,-10.106141090393066,-9.785482406616211,-10.149807929992676 -289,289,G39I,-0.146795925,-0.06749095,-0.017118722,-0.033975706,-0.672065611,-0.066558822,-0.085044732,-0.208547117,0.014665743,-0.04542732,-0.08955458,-0.007172792,-0.027064652,0.019291037,-0.08724244800000001,-0.45840476,-0.885726462,0.966541471,1.5578645930000001,-6.164445897,-6.177320816,-6.779677895,-4.94606192,-5.879094887000001,-7.0400739670000005,-5.19630328,-4.449055163,-9.734599113464355,-8.797981262207031,-9.45647144317627,-9.899588584899902,-9.686248779296875 -290,290,G39H,0.057380417999999996,-0.031844157000000005,-0.024760737999999997,0.009028342,-0.053090858,-0.033920782000000003,0.02622844,0.088532396,0.020842595,-0.026238516,-0.037449798,-0.04723196,-0.002289516,0.002937275,0.015119408999999999,-0.000261691,-0.105920025,1.2715196579999999,2.6078093630000003,-0.519858377,-0.205048973,-1.7921976469999998,0.47482469200000005,0.109065681,-1.185935638,-2.002675836,-2.541995413,-6.05993127822876,-5.167987823486328,-5.047944068908691,-5.813426494598389,-5.749842643737793 -291,291,G39K,-0.062437232999999995,-0.068582407,-0.025821892000000003,-0.019795206,-0.058406355,-0.040259006,0.034325895,-0.15920036,0.017189466,-0.08575820099999999,-0.051406613,-0.007031838,-0.044611946,-0.033597508,-0.005992903000000001,-0.024390306,-0.092422404,1.290710816,2.510587795,-0.19001675699999998,-0.814647453,-1.333052483,1.27691851,1.339176514,-1.418478874,-1.314500354,-1.251868861,-4.903114318847656,-4.133362293243408,-3.962952136993408,-4.119140625,-5.552929401397705 -292,292,G39M,0.024295061,-0.023338721,0.038627133,0.065037206,-0.157725137,-0.035261502,0.074765832,-0.02617571,0.15822439300000002,-0.05758651099999999,0.010909068999999999,0.001256386,0.075997879,0.049841561,0.08023285,-0.133789397,-0.18166087600000003,1.3870124259999999,2.26346973,-5.676114206,-5.449192062000001,-5.720592445,-5.155404076,-5.699067832999999,-6.3563146129999994,-4.8840753910000005,-5.058667077,-9.296142578125,-8.935848236083984,-9.184810638427734,-9.775585174560547,-9.54916763305664 -293,293,G39L,0.013008287,-0.046049085999999996,0.004741495,0.018861325,-0.17984062399999998,-0.040992234,0.018079874,0.0079367,0.045538765,-0.00752326,-0.084574911,0.036195931,-0.026712942000000003,0.029803871000000003,0.007918778000000001,-0.11534632,-0.24433492699999998,1.457873556,2.38527137,-5.367090427,-5.132965263,-5.8937718960000005,-4.6914292369999995,-4.9553363269999995,-6.161949409,-4.844458766,-5.120264332,-7.967520236968994,-8.073150634765625,-8.106645584106445,-8.489178657531738,-8.574088096618652 -294,294,G39N,-0.066750461,-0.042494082999999995,0.021690282999999998,-0.013061568,-0.119873344,-0.067529727,0.01096705,-0.144467971,0.190629885,-0.033411321,-0.051576845,-0.003898685,0.047279250999999994,-0.027336935,0.001213799,-0.045853334,-0.193893354,1.356320925,2.474560575,0.505353918,0.071031845,-0.110237968,0.91164846,1.684766953,-0.030439697,-0.82847736,-1.48990894,-4.235501766204834,-3.283543586730957,-4.645579814910889,-5.235759258270264,-4.799508094787598 -295,295,G39Q,0.09231882699999999,-0.024939292000000002,0.040726235,0.043551306,-0.004546878,-0.0041139259999999995,0.06438384700000001,0.12025380699999999,0.115921951,-0.000718656,-0.049159927,0.035170699,0.046281771,0.033272204,0.053830407999999996,0.013390613999999999,-0.022484369,1.1296082570000001,2.565841638,-0.461877621,-0.255409485,-1.3766799619999999,0.569256279,0.57329216,-1.819847099,-2.290038971,-1.841318519,-5.103806495666504,-4.741731643676758,-4.950382232666016,-6.137266159057617,-5.831656455993652 -296,296,G39P,-0.024957788999999998,-0.023815927999999997,-0.027370962999999998,-1.121844931,-2.311613621,-0.010413806,0.00324641,-0.053161988,-0.020773369,-0.033664415,-0.013967441,-0.042311783,-0.012430143000000001,-0.6698080670000001,-1.573881794,-2.280075389,-2.343151853,1.7315836080000002,1.314917237,-1.847444026,-0.902795815,-1.693601044,-1.3556551209999999,-1.9326427990000001,-3.352525352,-1.685002017,-1.355652664,-7.725709915161133,-7.346212387084961,-7.775059223175049,-9.030599594116211,-8.74807071685791 -297,297,G39S,-0.002436374,-0.033435636,0.019670545,0.011983062,-0.054611988,0.011320493000000001,0.041432215,-0.046304963,-0.077682494,-0.059012616,-0.007858656,0.03036699,0.008974099000000001,-0.020358901999999998,0.044325025,-0.020828144,-0.088395832,1.244729067,2.519156176,-0.96456564,-0.045579918,-1.325084709,-0.114295891,-1.408460999,-1.929406685,-1.6400115869999998,-1.625222164,-5.225606441497803,-4.667247295379639,-5.73815393447876,-6.341464996337891,-5.770848274230957 -298,298,G39R,0.035641591,-0.033352858,0.005775274,-0.003476574,-0.042271582,0.020859922,0.066997714,0.004285467,0.008114535,-0.058159105,-0.008546610999999999,-0.013072561000000002,0.024623107999999998,-0.03597721,0.029024062000000003,-0.031714287,-0.052828877,1.1952619359999999,2.412936074,-1.525261711,-1.30752224,-2.627572128,-0.349559258,-0.996594505,-2.345060425,-2.464090906,-2.207126206,-6.872514247894287,-6.316287994384766,-5.2392897605896,-6.064764976501465,-6.9389262199401855 -299,299,G39T,-0.016386802,0.005647872,0.004195953,-0.003613952,-0.22832972899999998,-0.019381086999999998,0.058367178,-0.09114078099999999,-0.010284956999999999,-0.051187279,0.062483022,-0.005450593,0.013842499,-0.056765373,0.04953747,-0.195486475,-0.261172983,1.4907399280000002,2.179379286,-2.804179903,-2.512974579,-2.897444412,-2.152659828,-3.0122260819999997,-3.445594612,-2.919464024,-3.01860165,-7.233470439910889,-6.443117141723633,-7.860881328582764,-7.772816181182861,-7.39736270904541 -300,300,G39W,-0.028442852,-0.009634091,0.022805716,0.027869203,-1.518050793,0.04987663,0.013734525,-0.070620228,0.096671626,-0.014407323,-0.004860859,0.003127785,0.04248364599999999,-0.025102963,0.080841368,-1.222811367,-1.813290219,0.625418467,1.332678085,-5.778988435,-6.06773716,-4.958365845,-5.07958783,-5.640652596,-7.148598747,-5.718269942999999,-5.42346743,-11.970636367797852,-12.896053314208984,-11.412485122680664,-12.373786926269531,-11.75662612915039 -301,301,G39V,-0.01442503,-0.019213564,-0.0022054139999999997,0.031149303,-0.19385058100000002,0.004199489,0.015830909,-0.044680968,0.079504576,-0.012016053,-0.026411075,0.007491108000000001,-0.011901935,0.018866093,0.043432513,-0.172887636,-0.214813525,1.474813867,2.236658008,-4.954182257,-4.526209999,-5.442019844,-3.551391846,-5.31167952,-5.939610077,-4.500919474,-4.311133515,-8.844837188720703,-8.263540267944336,-8.365840911865234,-9.177667617797852,-8.9126558303833 -302,302,G39Y,0.020294346,-0.057338407,0.054551467,0.011123401000000002,-0.821028526,-0.036919294,0.066726116,-0.026137424,-0.07454260900000001,-0.054360603,-0.060316210999999995,0.11705783800000001,-0.007954905,0.009527161,0.012719641,-0.49911105100000003,-1.142946,0.8808130940000001,1.505869713,-5.663334793,-5.608340179,-5.750419746,-4.488738876,-6.1968257289999995,-6.272349434,-6.708557884,-7.515189007999999,-10.05269718170166,-9.444150924682617,-9.907445907592773,-10.204939842224121,-9.775400161743164 -303,303,A40C,-0.105117456,-0.058843793,-0.07350666900000001,-0.010672741999999999,-1.570195837,0.10665125800000001,-0.075370656,-0.134864256,0.012803258999999999,-0.029218284,-0.088469301,-0.0290485,-0.11796483699999999,-0.009296999,-0.012048485,-1.4922726130000001,-1.64811906,0.717687273,1.32311566,-9.076272589,-9.335064285,-8.492576012,-10.19004385,-7.921906654,-9.441772141,-5.2637627,-3.171816914,-7.738095760345459,-7.340571403503418,-7.368588924407959,-8.873705863952637,-7.453107833862305 -304,304,A40E,-0.06306977700000001,0.00224266,-0.022318402,-0.570752814,-1.945210291,-0.01115715,-0.031995033,-0.094144521,0.0007542689999999999,0.023306201000000002,-0.018820882,-0.024049865,-0.020586939,-0.300689456,-0.840816172,-2.088340444,-1.8020801380000002,1.360774921,1.321849991,-8.268409337000001,-7.952552399,-8.905314232,-7.445812537999999,-7.368665732999999,-9.669701782,-5.624080508,-4.453475657,-8.994890213012695,-8.91348934173584,-9.01064682006836,-10.952406883239746,-9.142325401306152 -305,305,A40D,-0.05477293,0.005328475,-0.07492737299999999,-0.5582535470000001,-2.183416924,0.016838642,-0.057307363,-0.052238495999999995,-0.042208472000000004,0.029860412000000003,-0.019203462,-0.082346915,-0.06750783,-0.33490974,-0.781597353,-1.9787366469999998,-2.3880972000000003,1.484087322,1.3536285890000002,-9.115126808,-9.163704842000001,-9.302482513,-8.422225395,-8.19860421,-10.48861708,-6.013749868,-5.1557538339999995,-9.096709251403809,-9.064704895019531,-8.853218078613281,-11.007102966308594,-9.517988204956055 -306,306,A40G,-0.022685054,0.004718077,-0.044784395,0.015946553999999998,0.036494768,0.07070687,-0.027993855,-0.017376252,0.012355061,-0.014622848,0.024059001,-0.030248333999999998,-0.059320455,0.036542207,-0.004649100000000001,0.053630682,0.019358853,1.0961339490000002,2.600588944,-0.157101077,-0.468017731,-0.370095764,-0.025973915,-0.015459946,0.094041969,-1.312565006,0.5455119070000001,-4.572605133056641,-2.429048776626587,-3.8621926307678223,-4.487510681152344,-2.2140703201293945 -307,307,A40F,-0.10365336900000001,-0.03218484,-0.066587457,-1.287011271,-2.38393397,-0.002454684,-0.074610804,-0.13269593300000002,0.121574302,0.021951617000000003,-0.08632129599999999,-0.05502172,-0.07815319400000001,-0.875162581,-1.69885996,-1.996110743,-2.7717571960000003,2.128698785,1.51933801,-11.64279599,-12.05313537,-10.62418295,-15.23865742,-10.27326093,-10.02474327,-5.9435427139999994,-3.972397033,-8.948522567749023,-7.095167636871338,-9.707225799560547,-8.790037155151367,-9.048445701599121 -308,308,A40I,-0.094116576,-0.016606757,-0.023440445,-0.419960007,-1.756061106,-0.027451167000000002,-0.09981725,-0.08841590099999999,0.232006767,-0.048122929,0.014909415,-0.08361801599999999,0.036737127,-0.289957244,-0.549962769,-1.8782668230000001,-1.633855389,1.3985434630000002,1.356202295,-9.896002504,-11.21368596,-9.155639022999999,-11.12650687,-7.659156036000001,-10.32502463,-5.093383976,-3.349739284,-7.14735746383667,-5.145322322845459,-7.465907573699951,-7.22199010848999,-7.509697914123535 -309,309,A40H,-0.038118501,0.015070941000000001,-0.037597731,-1.4119757430000002,-2.788829598,0.000639644,-0.030914637000000002,-0.045322365,-0.019298419,0.003121459,0.027020422000000002,-0.063391787,-0.011803675,-0.802521851,-2.021429634,-2.386422312,-3.191236883,1.7821190630000001,1.264502866,-11.03103163,-11.40243981,-11.17949748,-11.79677647,-9.29396254,-11.48248183,-6.857150458,-5.841770338,-10.329297065734863,-8.215117454528809,-9.1318359375,-10.624579429626465,-9.872343063354492 -310,310,A40K,-0.09380111699999999,0.002298994,-0.155132471,-1.65717812,-2.764567772,0.049789712,-0.047072530999999994,-0.140529703,0.07926064,-0.008597839,0.013195827,-0.053988032000000005,-0.25627691,-1.137884574,-2.176471666,-2.659977884,-2.86915766,0.701938127,0.7348556490000001,-9.688825706,-10.28332585,-9.40587561,-10.43470382,-7.870976142999999,-10.44924711,-6.196180974,-4.554303697,-11.720159530639648,-8.987739562988281,-9.410943984985352,-9.93049430847168,-9.773210525512695 -311,311,A40M,-0.033500351,-0.014801061,-0.04989851,-0.022023066,-1.027279569,0.026258481,-0.012748255,-0.054252445999999996,0.082907491,-0.064487197,0.034885075,-0.08480563099999999,-0.014991388000000001,-0.033325443999999996,-0.010720688,-0.740214699,-1.314344438,0.756267169,1.407117765,-9.717348702999999,-10.64748917,-9.038460899,-11.74316519,-8.140702957,-9.016925301,-5.942501655,-5.028209158999999,-7.874391555786133,-5.077313423156738,-7.997139930725098,-7.841777801513672,-7.235963821411133 -312,312,A40L,-0.035231611,-0.010382304,-0.060243122999999996,-0.37685451600000003,-1.9776782069999999,-0.05162157,-0.041155282,-0.02930794,-0.03724315,-0.008569522,-0.012195085,-0.097916445,-0.022569801,-0.19898199100000002,-0.554727041,-2.008126796,-1.9472296169999999,1.3632733559999999,1.336924195,-9.107283621,-9.785855507,-8.010775436,-11.31403778,-7.249760802999999,-9.175988579,-4.965379495,-1.602838039,-6.2752814292907715,-3.5487589836120605,-7.853134632110596,-5.9206438064575195,-6.108237266540527 -313,313,A40N,-0.071405342,-0.053581252,-0.133728755,-0.040425194,-1.691389934,0.009492687,-0.116351687,-0.026458996000000002,-0.079912859,-0.122423627,0.015261124,-0.223380528,-0.044076980999999994,-0.078624613,-0.002225775,-1.697627936,-1.685151932,0.9804753559999999,1.329809824,-9.744348192999999,-10.28625108,-8.746045074,-10.45251505,-8.457188736,-10.77974103,-6.111152576,-4.520367236,-9.736648559570312,-6.522871971130371,-8.371015548706055,-9.647232055664062,-8.85853099822998 -314,314,A40Q,-0.053653174000000005,-0.007756886,-0.03961109,-0.036845682000000005,-0.538026022,0.006859272,-0.04486314,-0.062443208,-0.074541658,-0.000211073,-0.015302698,-0.028539832999999997,-0.050682347,-0.007673269,-0.066018094,-0.37028403,-0.7057680129999999,0.9682510390000001,1.610034084,-9.733010066,-10.40476114,-9.48382283,-10.2149325,-8.156155273,-10.40537859,-6.305973184,-5.44235615,-9.399625778198242,-8.125259399414062,-8.543333053588867,-9.575197219848633,-9.527105331420898 -315,315,A40P,-0.07962617,-0.034216582,-0.460880511,-1.8780468190000001,-2.675154675,-0.01378096,-0.062021519000000004,-0.097230821,-0.02543906,-0.041674732,-0.026758432000000002,-0.335497833,-0.586263189,-1.695279206,-2.060814432,-2.35490038,-2.99540897,1.469623919,0.776240657,-9.377176689,-9.265714676,-9.840518715,-9.610538567,-7.831010452,-10.33810104,-6.788661962999999,-5.546441044,-9.569992065429688,-8.792257308959961,-8.804954528808594,-9.258797645568848,-12.338727951049805 -316,316,A40S,-0.06026332,-0.017610296,-0.066653575,-0.015269671,-0.15070486,0.016593883,-0.064965621,-0.055561019,-0.002819204,-0.001710085,-0.033510507,-0.055722437,-0.077584712,0.020832589,-0.05137193,-0.100199099,-0.201210621,1.250644771,2.261861384,-5.264974377,-5.080157265,-4.909791092,-5.498686325,-4.608633636,-6.227603568999999,-4.436118249,-3.761126163,-7.133923053741455,-4.908726215362549,-5.98841667175293,-6.470672607421875,-7.032675743103027 -317,317,A40R,-0.092813762,-0.008191595,-0.37600203,-1.83979727,-2.49902172,0.036859048,-0.06776038,-0.11786714400000001,0.000722387,-0.010637048999999999,-0.005746141,-0.299719432,-0.45228462700000005,-1.4758914140000001,-2.203703125,-2.43264754,-2.5653959,1.568285453,0.86188763,-9.219595867999999,-10.81506764,-10.715207800000002,-9.241713127,-6.7980230939999995,-8.527967674,-4.636907077,-4.139446339,-11.249321937561035,-8.788243293762207,-9.23529052734375,-9.388894081115723,-9.647974967956543 -318,318,A40T,-0.060567583,-0.00658904,-0.065936878,0.008830971,-0.47443829200000004,0.032575306,-0.065806562,-0.055328603,0.013220431999999999,-0.008632731999999999,-0.004545347,-0.084649827,-0.047223928,0.010730045,0.006931896,-0.372457896,-0.576418687,1.5843888030000002,2.034189763,-6.061827898,-6.02127092,-6.374774521,-6.46300911,-5.088188705,-6.3618962329999995,-4.341103513999999,-3.264619475,-6.009793281555176,-5.412333011627197,-6.403622627258301,-6.841503620147705,-7.446486949920654 -319,319,A40W,-0.086372996,0.034520409,-0.066124692,-0.3816922,-1.9231337169999998,0.053237823,-0.060273583,-0.11247240900000001,0.028829628,0.006846049,0.062194768,-0.09071809800000001,-0.041531285,-0.22501643699999999,-0.538367963,-1.8176908219999999,-2.028576611,1.3696194869999998,1.3634874019999998,-9.56096591,-9.665654472,-8.352868759,-12.55354668,-7.67288636,-9.559873283,-5.210615845,-4.674515845,-11.646443367004395,-9.461265563964844,-10.12453556060791,-11.387097358703613,-10.576045036315918 -320,320,A40V,-0.028467917000000002,0.012072437,-0.034846281,0.011812778000000001,-1.766813589,-0.002176936,-0.021491331000000002,-0.035444502999999995,0.017451831,0.02022624,0.0039186329999999995,-0.043448358,-0.026244204,0.062826097,-0.039200542000000005,-1.531854271,-2.001772906,0.620901931,1.315117069,-7.295956834,-8.534280052,-6.822046332999999,-8.301037498,-6.192158562,-6.6302617260000005,-3.547302239,-1.71421689,-5.08971643447876,-3.971540927886963,-5.648050308227539,-5.4599127769470215,-6.062099456787109 -321,321,A40Y,0.016384013,-0.002946518,0.029702202,-1.492155119,-2.342321982,0.049562407,0.04584061,-0.013072585,-0.0072198440000000004,-0.00249084,-0.0034021959999999997,-0.010566461999999999,0.069970865,-1.09567298,-1.8886372569999998,-2.024139467,-2.660504497,2.277840302,1.555949434,-12.55424095,-12.88309465,-11.62149262,-15.76607797,-11.04554511,-11.45499439,-6.028284081,-4.387712206000001,-10.724807739257812,-8.104316711425781,-9.771618843078613,-10.203402519226074,-10.001367568969727 -322,322,R41A,0.014175223,0.0011350330000000001,-0.005289116,-0.016504862,-0.329086585,-0.024127067000000002,0.028168900000000004,0.000181545,-0.000805686,0.013836642,-0.011566576,0.026436757999999998,-0.03701499,0.016264429,-0.049274152,-0.24748700399999998,-0.410686165,1.075702019,1.8031354780000002,-7.9110335329999995,-8.454929474,-7.594357742000001,-8.198534317,-6.476770332,-8.830575798,-6.496754075,-3.516781603,-7.905562877655029,-9.899189949035645,-9.76529312133789,-9.656904220581055,-10.421418190002441 -323,323,R41C,0.036169782000000004,0.038635089,0.014229368999999999,-0.348469811,-1.6935093490000002,0.013772578,0.076069142,-0.003729578,0.107267498,0.003083749,0.074186428,0.001910194,0.026548544,-0.161939826,-0.534999795,-1.654782867,-1.73223583,0.995172686,1.3341927,-10.90790401,-11.80925703,-10.84698395,-11.5463815,-9.791303535,-10.54559406,-10.07774203,-9.472095529,-9.06146240234375,-9.403785705566406,-10.11247730255127,-10.012134552001953,-12.061810493469238 -324,324,R41E,0.026797447000000002,-0.143173155,-0.006802989000000001,0.11204932699999999,-1.8836354180000001,-0.17588869699999998,0.076386644,-0.022791751000000002,-0.304943142,-0.097306448,-0.189039861,0.008005655,-0.021611632000000002,0.14380294300000002,0.08029571099999999,-1.76744391,-1.999826925,0.582131696,1.3039415429999999,-7.229512217999999,-8.779807655,-7.426165421,-7.652133903999999,-5.51179612,-6.77765799,-5.996768207000001,-2.101125874,-9.360991477966309,-10.675743103027344,-10.684393882751465,-11.677186012268066,-11.153650283813477 -325,325,R41D,0.0011484730000000001,0.034898487,0.031915898,0.011613871000000001,-1.9552650969999998,-0.055899153,0.026722857000000003,-0.024425912,0.045136250999999995,0.026786535,0.043010439000000004,0.053678644000000005,0.010153152,0.06180162,-0.038573879,-1.63579779,-2.274732404,0.554420618,1.3082232059999999,-7.130674689,-9.39888298,-7.688447707999999,-7.349585938,-4.913296463,-6.303160355,-5.369035478,-2.072761667,-10.21397876739502,-11.667473793029785,-11.368764877319336,-11.972299575805664,-11.64970588684082 -326,326,R41G,-0.045227413,-0.008654291,-0.013518428999999998,-0.272394316,-1.9746788119999998,-0.005760957,-0.015736165,-0.07471866099999999,-0.011328907,-0.017192073999999998,-0.000116507,-0.012607344,-0.014429513,-0.17475639199999998,-0.370032239,-1.870903855,-2.0784537690000002,1.113777737,1.325451707,-8.174043091,-8.158225319,-8.015790512,-8.991767075,-7.331984467000001,-8.372448082,-6.738433802,-4.347049413,-9.079644203186035,-10.151632308959961,-10.918009757995605,-10.44109058380127,-11.310819625854492 -327,327,R41F,-0.031995134,-0.066353486,0.024488762999999997,-0.021359166000000002,-1.159161857,-0.023862402999999997,-0.043594107,-0.020396161,0.215558843,-0.057574732,-0.07513224,-0.005845456999999999,0.054822983,-0.073462555,0.030744224,-0.878205035,-1.440118679,1.015772328,1.4373404509999999,-9.044889124,-9.681272629,-9.217082642000001,-9.704488426000001,-7.416704666,-9.204897255,-7.12170323,-4.546142434,-10.166654586791992,-11.690156936645508,-12.112602233886719,-9.76787281036377,-13.20234489440918 -328,328,R41I,0.051475337999999995,0.056238444000000005,0.07226571,0.015032337,-0.608879904,-0.080332022,0.044943208,0.058007467,0.066192163,0.017147786,0.095329102,0.02071762,0.12381379999999999,0.029124832000000003,0.000939842,-0.382953871,-0.834805937,0.684508662,1.4789609119999998,-7.823989711,-8.081413071,-8.274350647,-9.372880371,-5.779226883,-7.612077583,-6.078301101,-3.407516335,-9.439924240112305,-10.171514511108398,-10.726688385009766,-10.611928939819336,-11.064841270446777 -329,329,R41H,0.024153756000000002,0.007820113,0.030577838,0.025247472000000003,0.021122042,-0.042750288,0.033308045,0.014999466999999999,-0.0014525470000000002,0.020375901000000002,-0.004735675,0.07769440400000001,-0.016538728,0.023690037999999997,0.026804905,0.032541371,0.009702711999999999,1.33983753,2.954958155,-4.14439126,-4.866262558,-4.056394279,-4.957537155,-3.7322924580000003,-3.109469849,-5.080128381000001,-2.8438455460000003,-6.704842567443848,-7.7656168937683105,-7.6620283126831055,-7.365297317504883,-8.655671119689941 -330,330,R41K,0.07174505099999999,0.129526415,-0.065812197,-0.092824461,-0.157427045,-0.15066343,0.014729743,0.128760359,0.186418552,0.075180687,0.183872142,0.020970632,-0.152595025,-0.20934360300000002,0.023694682,-0.008119517,-0.306734572,1.304766772,2.428468314,-4.021878603999999,-4.007838219,-3.941798958,-5.133931519,-3.0674591980000003,-3.958365128,-3.127525866,-1.831786823,-5.015340805053711,-6.015601634979248,-5.880324363708496,-6.611541748046875,-6.641529560089111 -331,331,R41M,-0.042544174000000004,0.050165097,0.046365118,-0.019561203,-0.282237032,-0.267229854,-0.05925031,-0.025838037,-0.165445685,0.043144455,0.057185739000000006,0.121949007,-0.029218772,0.036169064,-0.075291469,-0.156783747,-0.407690316,1.209663148,2.069648807,-9.12365246,-9.249342278,-9.344493996,-10.27675532,-7.339047104,-9.408623604,-7.491713806,-5.155772824,-10.049803733825684,-10.40523910522461,-10.675456047058105,-10.78768253326416,-11.534825325012207 -332,332,R41L,0.028565672,0.012327097,0.000829758,0.009176213,-0.342520526,-0.022229294,0.048534741,0.008596603000000001,0.022134968999999997,0.02566173,-0.001007536,0.020678276000000002,-0.01901876,0.013369368000000001,0.004983057,-0.28509362899999996,-0.39994742200000005,1.043328142,1.7371251269999999,-7.594377237000001,-7.865121718999999,-8.056239372,-8.804315979,-5.399986244,-7.84622287,-6.203619382,-3.71831129,-9.0465669631958,-10.082796096801758,-10.258666038513184,-9.31600284576416,-10.937960624694824 -333,333,R41N,0.045318359,0.041106422000000004,0.05293636400000001,-0.001832782,-0.225044473,-0.028365495,0.046641428,0.04399529,-0.050198333,0.024554901,0.057657942999999996,0.005892296,0.099980431,-0.009939939,0.006274376,-0.205555551,-0.244533394,1.354411976,2.0717306559999997,-7.147413536,-8.834672752000001,-6.638065598,-8.063551537,-6.002389236,-6.198388557,-6.067181409,-2.957229038,-8.385147094726562,-8.644335746765137,-9.313288688659668,-9.274251937866211,-9.041183471679688 -334,334,R41Q,0.079704802,-0.032338335,-0.004277411,-0.009874873000000001,-0.280324444,-0.02242655,0.128997316,0.030412288,0.079645356,-0.130581243,0.06590457400000001,-0.005870749000000001,-0.002684073,-0.094267144,0.074517398,-0.291964603,-0.268684284,1.725405224,2.2882589490000003,-5.176583997,-6.3755518879999995,-5.0122434160000005,-5.651072571,-4.208332008,-4.6357200999999995,-5.491668112,-2.406481727,-6.683002471923828,-7.434648036956787,-7.846261501312256,-7.782236099243164,-8.374531745910645 -335,335,R41P,-0.005156844,-0.013415779,0.004111325999999999,-0.0033494809999999996,-0.09971374300000001,-0.042323383,-0.002951166,-0.0073625209999999995,-0.018683797,0.002332838,-0.029164396000000002,0.031672386000000004,-0.023449735,0.025787402999999997,-0.032486364,-0.071686803,-0.127740683,1.4339148080000002,2.585515661,-8.540180766,-8.880432442,-8.313068787,-8.920650367999999,-7.153762436,-9.4329898,-7.461681698,-4.917740662,-9.61563777923584,-11.775900840759277,-12.384231567382812,-11.911195755004883,-12.396215438842773 -336,336,R41S,-0.010113505,0.02803689,0.017323919,0.017152012,-0.309092945,-0.028761482999999997,0.007218868000000001,-0.027445877999999996,0.049795038,0.045346295999999994,0.010727483000000001,0.038479689,-0.003831852,0.053735448,-0.019431425,-0.20949095399999998,-0.408694936,1.1776558609999999,1.9720012530000002,-6.728092082000001,-7.885393700000001,-6.289473663,-6.690786934,-5.698657974,-7.07614814,-5.612795017000001,-2.758965204,-7.19688606262207,-7.610361576080322,-8.863536834716797,-8.825249671936035,-8.851814270019531 -337,337,R41T,0.005292563,-0.010290918000000001,0.030309218,-0.037575382000000004,-0.286286649,-0.018796609,0.020895518000000002,-0.010310393000000001,0.04570781,-0.02191123,0.001329394,0.04627892,0.014339515,-0.024637909,-0.050512854,-0.22418722300000002,-0.348386074,1.320921124,1.996132372,-5.357786441,-6.790398979,-4.410879402,-5.857380142,-3.788015831,-5.942257851,-4.363698391000001,-1.135423417,-7.514289855957031,-7.62820291519165,-8.694524765014648,-8.921616554260254,-8.651298522949219 -338,338,R41W,0.123407561,-0.15404347300000001,-0.08580555699999999,-0.11465087800000001,-2.024107135,-0.07270929,0.06957841099999999,0.17723671100000002,-0.010752571,-0.207319507,-0.100767438,-0.128214092,-0.043397020999999994,-0.202713025,-0.02658873,-2.103236012,-1.9449782569999998,1.2796429329999999,1.31631113,-9.193398578,-10.30094853,-9.016841087000001,-9.764631873999999,-8.5371091,-8.347462296,-8.291228436,-6.660180437,-10.493106842041016,-11.95347785949707,-11.286844253540039,-10.700773239135742,-13.190069198608398 -339,339,R41V,-0.046817501,0.004022583,0.020972942999999997,0.011967721,-0.49186862299999995,-0.000111315,-0.044483977,-0.049151024,0.049013095,0.010506042,-0.002460877,0.043824623,-0.0018787379999999998,0.06606677799999999,-0.042131336,-0.307287876,-0.67644937,0.8938577440000001,1.61357601,-6.939408635,-7.161310951,-7.2247063979999995,-8.14816021,-5.267458839,-6.895406776000001,-5.922715871,-2.604440072,-8.194480895996094,-10.177963256835938,-10.282049179077148,-9.943121910095215,-10.521259307861328 -340,340,R41Y,0.030734586,0.03998636,0.031102226,0.04914011,-0.608998027,-0.007637756,0.032034601,0.02943457,0.010842043,-0.021172895,0.101145615,0.04225349900000001,0.019950953,0.037836224,0.06044399599999999,-0.501176021,-0.716820033,0.57128907,1.4084087090000001,-8.450557805,-8.96179113,-9.236753685,-9.369793518,-7.415555893,-7.268894798,-6.553774327,-5.110849356,-10.411787033081055,-11.171222686767578,-11.284733772277832,-10.239453315734863,-12.791001319885254 -341,341,V42A,-0.048834558,-0.054367770999999995,-0.020670072,-0.066569947,-1.919095692,0.0010269839999999999,-0.075822649,-0.021846467,0.037153859,-0.067905561,-0.04082998,-0.034508999,-0.006831145,-0.00888129,-0.12425860400000001,-1.7661121169999998,-2.072079266,0.754085873,1.310172393,-5.750713779,-5.368870941,-4.9861660080000005,-5.493981498999999,-4.625452965,-8.279097481,-5.589696845,-1.6665650859999999,-5.626071929931641,-7.367988109588623,-6.715466022491455,-6.040186882019043,-7.605292320251465 -342,342,V42C,-0.016306958,-0.010139181,0.027446027,-0.022494841,-1.543953069,-0.11035763900000001,-0.09253013199999999,0.059916217,0.056092172,-0.067245685,0.046967324000000005,0.01205723,0.042834824,0.074412597,-0.119402279,-1.7239684769999999,-1.363937661,0.717562409,1.310414273,-11.24883848,-10.287272300000001,-11.55317311,-12.45897812,-9.921269752999999,-12.02349913,-8.131286207,-4.247702166,-8.655068397521973,-10.274088859558105,-7.9975810050964355,-9.989770889282227,-9.727331161499023 -343,343,V42E,-0.11745233199999999,-1.014123925,-2.4105924219999997,-2.697324166,-2.394525721,0.06726708099999999,-0.122491932,-0.11241273199999999,-0.04302231,-0.927745342,-1.100502508,-2.444708228,-2.376476615,-2.5014358530000003,-2.893212478,-2.256454649,-2.532596793,0.57738801,-0.603679795,-13.28097255,-12.11638589,-12.71482513,-13.80879637,-11.11338464,-16.6514707,-9.730004057,-6.711900429,-11.979823112487793,-15.204357147216797,-12.296197891235352,-13.01648998260498,-11.97142219543457 -344,344,V42D,-0.127822416,-1.305537714,-2.147604355,-2.4343360990000003,-2.884112643,0.037513529,-0.125833267,-0.129811565,-0.053346499000000006,-1.2677582170000001,-1.343317211,-2.123075422,-2.172133287,-1.878773051,-2.9898991460000004,-2.837911829,-2.9303134560000004,3.527073422,1.2370576340000001,-14.22170071,-12.82961925,-13.59708347,-15.42674113,-11.75541148,-17.4996482,-9.590015922000001,-6.711900429,-12.298171997070312,-16.171062469482422,-12.938393592834473,-12.861895561218262,-12.69023323059082 -345,345,V42G,-0.073093496,-0.251672928,-1.4634803159999998,-2.0787464940000002,-1.921353464,-0.0045799379999999995,-0.069322555,-0.07686443700000001,-0.025710458,-0.15724022699999998,-0.34610562899999997,-1.536847106,-1.390113525,-2.420574549,-1.736918438,-2.622751376,-1.219955552,1.0123225040000001,0.05798549099999999,-12.13901232,-11.28409974,-12.17010969,-13.26162738,-9.293472969,-14.68575185,-7.179026853,-1.3593856819999999,-8.636045455932617,-11.602815628051758,-9.316431999206543,-9.7803316116333,-11.430408477783203 -346,346,V42F,-0.109596985,-0.152504425,-0.059699559000000006,-0.097575803,-0.057509392,-0.031474665,-0.16458882800000002,-0.054605142,-0.062326592,-0.227243782,-0.07776506700000001,-0.026609581,-0.09278953599999999,-0.060107365,-0.135044241,-0.104991159,-0.010027625,1.355218569,2.2860847719999997,-8.167220334,-6.880758537,-8.669246216,-9.637797974,-8.584950974,-7.063347969,-5.451060126000001,-1.854021945,-6.102940559387207,-8.172148704528809,-7.780505657196045,-6.753716945648193,-5.732767581939697 -347,347,V42I,-0.008769621,-0.041817101,-0.059958037,-0.089884691,-0.201484743,-0.113389739,-0.091190361,0.073651119,0.060683167999999996,-0.0945148,0.010880598,-0.099594326,-0.020321747,-0.042378597999999996,-0.13739078300000002,-0.180962278,-0.222007208,1.5954643919999998,2.286032838,-1.45597131,-1.2991952359999999,-1.8273705830000002,-0.7286336520000001,-2.2808714219999997,-1.14378566,-2.7092951430000003,-0.430015489,-2.9701128005981445,-3.3583927154541016,-3.5478954315185547,-3.595277786254883,-2.835268497467041 -348,348,V42H,-0.095633241,-0.077905631,-0.662117764,-2.0259092709999997,-2.563731445,-0.032851672,-0.134606227,-0.056660255,0.050092344000000004,-0.11033037300000001,-0.045480889000000004,-0.54762758,-0.776607948,-1.789991781,-2.26182676,-2.402343074,-2.7251198160000003,1.847976124,0.864868008,-14.14067017,-13.313238199999999,-12.76463396,-15.27925266,-11.57984059,-17.76638544,-8.762214041,-5.51012779,-11.062368392944336,-12.882972717285156,-10.214773178100586,-10.308737754821777,-8.89311695098877 -349,349,V42K,-0.076907735,-1.086399835,-2.316118179,-2.452334925,-2.601081474,-0.076715539,-0.112720561,-0.041094909,-0.002590601,-0.9820926209999999,-1.190707048,-2.186744502,-2.445491856,-2.243472126,-2.661197724,-2.6005509140000003,-2.601612034,0.5846008420000001,-0.61795067,-12.3862076,-11.57915673,-10.83522979,-12.07693784,-10.42470998,-17.01500368,-8.226119872,-4.937671666,-13.459478378295898,-14.974590301513672,-10.956965446472168,-12.067922592163086,-10.23280143737793 -350,350,V42M,-0.08518411199999999,0.025537307999999998,0.013050768,-0.0322342,-0.099695113,-0.044139457,-0.117065315,-0.053302909,0.041422846,0.07224185799999999,-0.021167243,-0.011886325,0.037987861,0.02924951,-0.09371791,-0.06458784299999999,-0.134802382,1.2787204159999999,2.428647026,-8.580666524,-6.122465477,-8.733184319,-8.781018852,-9.204126373,-10.062537599999999,-6.257280428,-3.2321210469999997,-5.912476539611816,-7.2524189949035645,-6.071008205413818,-6.299620151519775,-5.908903121948242 -351,351,V42L,-0.073064142,-0.07159737599999999,-0.06822167700000001,-0.056173158,-0.143120966,-0.09379791300000001,-0.119408857,-0.026719426,0.039146222,-0.057165336,-0.086029415,-0.037557869,-0.09888548400000001,0.02185562,-0.134201936,-0.095157714,-0.191084217,1.210472728,2.210855545,-5.410240579,-2.8762259219999997,-5.385057892000001,-5.770379646,-6.67588121,-6.3436582260000005,-4.820620695,0.251478343,-3.2135229110717773,-4.712320327758789,-2.0185189247131348,-3.1993842124938965,-1.7243156433105469 -352,352,V42N,-0.021236026,-0.029316436,-0.127444829,-1.244736528,-2.725804065,-0.044934684,-0.036450231,-0.00602182,0.047244802,-0.09392831199999999,0.035295441000000004,-0.17147539399999998,-0.083414264,-0.7320585270000001,-1.757414529,-2.7123866039999998,-2.739221525,1.250531157,0.9559068190000001,-13.83500946,-12.65718384,-14.47535558,-14.17697746,-10.85414404,-17.01138639,-8.415453989,-4.527639932,-11.363149642944336,-12.307615280151367,-10.747264862060547,-9.858975410461426,-10.104659080505371 -353,353,V42Q,-0.138643744,-0.297253804,-1.7020567290000002,-2.659999813,-2.720700732,0.014348893,-0.166878043,-0.11040944400000001,-0.041392685,-0.21220446699999998,-0.382303141,-1.4714584080000002,-1.932655049,-2.268548722,-3.0514509039999997,-2.44953625,-2.9918652139999997,1.250958046,0.116424931,-12.44468009,-10.96726592,-11.74995643,-12.20772287,-10.64473772,-16.65371751,-8.487173463,-5.157868608,-11.246063232421875,-13.297051429748535,-9.817209243774414,-10.795607566833496,-9.297723770141602 -354,354,V42P,-0.074100851,-1.4501134530000002,-2.103837742,-2.3806974569999997,-3.3304740010000002,-0.017304509,-0.106523379,-0.041678322000000004,-0.032663874,-1.440946745,-1.459280161,-2.135852895,-2.071822589,-2.220609243,-2.540785671,-2.79953678,-3.861411222,-0.035027696000000004,-0.897457807,-11.63433995,-11.34192043,-10.60614514,-11.55235542,-10.25729943,-14.41397932,-7.41640401,-2.364376123,-9.186576843261719,-11.714844703674316,-9.503962516784668,-10.421875,-12.042495727539062 -355,355,V42S,-0.11661343,-0.080188993,-0.301495143,-1.842300377,-2.10528659,-0.00048112199999999995,-0.148309415,-0.08491744400000001,-0.079401868,-0.066693012,-0.093684974,-0.30012769300000003,-0.302862592,-1.4376785109999999,-2.2469222419999997,-2.0579987330000002,-2.152574446,2.796002436,1.7991317869999999,-10.11553294,-9.464000038,-9.996746544,-10.66503382,-8.015808113,-12.436076199999999,-7.245395211,-3.894109901,-8.532166481018066,-10.159442901611328,-8.472820281982422,-7.732968807220459,-8.56823444366455 -356,356,V42R,-0.064301108,-1.301568907,-2.06483162,-2.2058210259999997,-2.5417970309999998,0.00557498,-0.09815975199999999,-0.030442463,-0.041392685,-1.365721917,-1.237415896,-2.044947863,-2.0847153769999998,-2.226614224,-2.185027827,-3.0608142660000004,-2.022779795,0.22643203399999998,-0.811148775,-13.38400421,-11.10321332,-12.44210976,-13.50770814,-10.85702736,-19.00996249,-8.845569055,-6.055786782999999,-12.295431137084961,-13.522390365600586,-9.067245483398438,-11.264435768127441,-9.71863079071045 -357,357,V42T,-0.076838235,-0.047996937999999996,-0.03088769,-0.05184063,-1.804800391,0.000422425,-0.093293286,-0.060383184000000006,0.171710638,-0.049903320999999994,-0.046090554000000006,-0.039315214,-0.022460166,0.015879105,-0.119560364,-1.556925347,-2.052675435,0.638661461,1.315258182,-8.216012994,-8.130946434,-7.172704544,-8.420498749,-6.613806557,-10.74210869,-6.494612137000001,-2.4126573319999998,-7.031354904174805,-7.846296310424805,-6.7231292724609375,-5.701380729675293,-7.018575668334961 -358,358,V42W,-0.037367618,-0.062087257,-0.012738049,-0.029497987000000003,-0.7480410390000001,-0.077508068,-0.106629469,0.031894233,0.190215902,-0.027850112000000003,-0.09632440099999999,-0.034456157,0.008980059,0.035281475,-0.09427744800000001,-0.6093248379999999,-0.886757239,0.691407063,1.4091411090000001,-12.54632902,-11.01480553,-11.77137137,-13.93374648,-11.03126887,-14.98045285,-7.133334924,-2.915912394,-9.84210205078125,-12.982572555541992,-9.663763999938965,-11.252704620361328,-10.10689926147461 -359,359,V42Y,-0.10023045300000001,-0.083763121,-0.140420345,-0.112904749,-1.576655735,-0.05267585599999999,-0.156794085,-0.04366682,-0.02208753,-0.041996570999999996,-0.125529671,-0.12237496099999999,-0.158465729,0.10031626199999999,-0.32612576,-1.946958606,-1.206352864,0.545766663,1.295458651,-11.60412526,-11.02745354,-11.49822708,-13.49940833,-10.31264599,-11.68289134,-7.77055538,-1.747340932,-8.415229797363281,-11.574374198913574,-10.147964477539062,-9.194209098815918,-7.859494686126709 -360,360,G43A,-0.010556268,0.018114292,-0.01299378,-0.027215972,-1.171754763,-0.019636857,-0.004146897,-0.016965638999999998,-0.042451105,-0.033158722,0.069387306,-0.024616205,-0.001371355,-0.045120507000000004,-0.009311436999999999,-0.8256540659999999,-1.517855459,1.19388807,1.5105627069999998,-8.305482494,-8.844026169,-7.229489586000001,-9.348851646,-9.032743431,-7.072301636000001,-5.308879032,-2.424908077,-8.649784088134766,-11.003278732299805,-8.116669654846191,-8.749807357788086,-10.209087371826172 -361,361,G43C,-0.079963376,0.005204986,-0.556814425,-1.7950161119999999,-2.6954737860000004,0.067136271,-0.061502195,-0.098424557,-0.028688526000000002,-0.022773292,0.033183264,-0.37713037200000005,-0.736498477,-1.494415988,-2.095616235,-2.367148769,-3.023798802,1.64219998,0.885153842,-10.22108136,-11.22729279,-8.533606812,-10.73346894,-9.758839691,-10.85219858,-6.64903826,-4.61918005,-11.146929740905762,-13.263018608093262,-11.631570816040039,-12.262107849121094,-12.89224910736084 -362,362,G43E,-0.063096545,-1.523835756,-2.3057385530000003,-2.228948903,-2.814362219,0.023195865,-0.051892533,-0.074300557,-0.104480941,-1.374654321,-1.67301719,-2.189533394,-2.421943711,-1.984599716,-2.47329809,-2.431363764,-3.1973606739999996,0.29382053399999997,-0.8577233340000001,-13.75971575,-14.16470794,-13.16658147,-14.91205823,-12.94175538,-13.61347571,-8.138438834,-6.28505637,-12.710578918457031,-18.10273551940918,-13.587206840515137,-13.618415832519531,-15.401928901672363 -363,363,G43D,-0.035579313,-1.308985898,-2.552514988,-2.32521034,-2.7345323969999997,-0.019801497,-0.023699283999999998,-0.047459342,-0.163089127,-1.48983322,-1.128138576,-2.55335422,-2.551675755,-1.9504805330000001,-2.699940147,-2.443002072,-3.026062722,0.24883133699999999,-1.063040398,-15.17983752,-15.56843794,-15.6326565,-15.58917384,-14.22829707,-14.88062227,-10.41556539,-10.13728232,-10.764053344726562,-16.837448120117188,-12.001160621643066,-12.211990356445312,-14.142714500427246 -364,364,G43F,0.008573815,-0.8487223,-2.2520415480000002,-2.675251899,-2.973649581,0.088505553,0.032188896,-0.015041266999999999,0.08295567200000001,-0.71298812,-0.98445648,-2.280613864,-2.223469232,-2.376710181,-2.973793616,-2.9484129660000002,-2.9988861960000004,0.374740526,-0.553456275,-15.1100951,-16.72568621,-15.84018517,-15.40007823,-13.21064915,-14.37387673,-7.646789435,-4.426916876,-13.844407081604004,-16.71025276184082,-15.019637107849121,-14.109341621398926,-17.398338317871094 -365,365,G43I,-0.016930748,-1.3014201440000002,-1.757612138,-2.442261861,-2.97922017,-0.015234464,-0.022679447000000002,-0.011182049,-0.14729486,-1.3540365559999998,-1.248803731,-1.6557967219999998,-1.8594275530000002,-2.177861771,-2.70666195,-2.925655815,-3.032784525,3.3530229080000002,1.148274499,-17.55281205,-18.06876511,-18.82870093,-18.24917424,-15.515943799999999,-17.10147619,-10.47188074,-10.31466836,-14.376949310302734,-17.57539176940918,-15.754085540771484,-13.387545585632324,-17.13312339782715 -366,366,G43H,-0.017279964,-1.446754015,-2.094197529,-2.3378969069999997,-2.9373245860000003,0.032580747,0.008006810999999999,-0.042566739000000006,-0.15624970300000002,-1.255750014,-1.637758016,-2.1830512669999997,-2.00534379,-2.279147584,-2.39664623,-2.8508503689999998,-3.023798802,0.743142448,-0.725932108,-13.6477212,-15.38191731,-14.16540439,-13.30923399,-12.44064476,-12.94140556,-7.236583262000001,-4.60622181,-13.196537017822266,-15.643147468566895,-13.945018768310547,-12.57333755493164,-15.673425674438477 -367,367,G43K,-0.081894555,-1.5271984269999999,-2.361468899,-2.483649254,-3.171122562,-0.012630415,-0.045896812,-0.117892297,-0.052638585999999994,-1.310823958,-1.7435728959999999,-2.230438382,-2.492499416,-2.201595963,-2.765702545,-3.074328743,-3.26791638,0.471716662,-0.7914996999999999,-14.73169277,-15.993635500000002,-14.43238011,-15.44536844,-13.76628203,-14.02079778,-8.359684763999999,-6.499039112,-15.246200561523438,-19.758464813232422,-15.352113723754883,-12.934088706970215,-17.035781860351562 -368,368,G43M,0.013589131,-1.224458034,-2.278992232,-2.401172587,-3.0261765260000004,0.017405336,0.0464152,-0.019236938999999998,-0.082752623,-1.1320756,-1.316840467,-2.294728073,-2.263256391,-2.5669156490000002,-2.235429524,-2.837588438,-3.2147646130000003,0.64600267,-0.6805446620000001,-15.70775851,-16.42395145,-16.03231233,-18.06882285,-13.71296685,-14.30073907,-9.130346524,-7.189066379,-15.151864051818848,-17.944204330444336,-15.667987823486328,-14.616816520690918,-16.432086944580078 -369,369,G43L,-0.054140074,-1.212846133,-2.325670353,-2.7372657819999997,-3.5752540880000003,0.001630185,-0.041433008,-0.06684714,-0.108203337,-1.1040181009999999,-1.321674164,-2.27668357,-2.374657135,-2.31478794,-3.159743624,-3.488550717,-3.661957459,0.7119399609999999,-0.655279386,-16.25556056,-16.9073942,-16.38049994,-17.86799541,-14.43660992,-15.68530334,-8.650885915,-6.3501416289999995,-14.329330444335938,-17.4354248046875,-14.882418632507324,-13.296889305114746,-16.122074127197266 -370,370,G43N,-0.036299714,-1.39928115,-2.081234563,-2.675656253,-2.934463313,0.006664864,-0.018961927,-0.053637501,-0.166814064,-1.632810823,-1.165751477,-2.427486511,-1.734982614,-2.8246128230000003,-2.526699682,-2.618164358,-3.250762267,-0.07679628,-1.106848059,-13.86738216,-15.78238918,-13.52849535,-13.71421355,-12.11440718,-14.19740553,-8.326077533,-6.143917468,-11.03858757019043,-16.245445251464844,-12.659370422363281,-11.371183395385742,-14.981689453125 -371,371,G43Q,-0.041755758,-1.234980317,-2.2598845340000002,-2.683094885,-2.981492567,0.020733279,-0.035094436,-0.04841708,-0.140367317,-1.288750274,-1.181210359,-1.9150215309999998,-2.6047475369999997,-2.61317784,-2.753011929,-2.883850629,-3.079134505,2.430715184,0.18473790399999998,-13.73389587,-14.81988088,-13.49472028,-14.32991122,-12.37068157,-13.65428542,-7.841259302999999,-5.190785441,-14.6201810836792,-18.09534454345703,-14.706718444824219,-13.250727653503418,-16.43856430053711 -372,372,G43P,-0.032452791,-1.572854555,-2.1320325430000002,-2.520256271,-3.0906879760000003,-0.004283567,-0.029746622,-0.035158959,-0.11638915400000001,-1.5801126540000001,-1.565596456,-2.131750293,-2.132314792,-2.424141255,-2.616371286,-2.761760834,-3.4196151169999998,-0.019045775,-1.037995266,-15.60811012,-16.21856866,-15.28665533,-16.39593468,-14.96997552,-15.16941643,-10.47188074,-10.31466851,-13.906481742858887,-18.685068130493164,-15.053473472595215,-15.5050048828125,-16.779191970825195 -373,373,G43S,-0.013414771,0.031663285,-0.0031158,-0.023933613,-1.823495968,-0.046129330999999996,-0.022707835,-0.004121706,-0.01117313,-0.007488021,0.07081459,-0.032337035,0.026105435,-0.023249118,-0.024618107,-1.4924380130000001,-2.154553923,0.92565475,1.340169118,-8.99387086,-10.34149201,-7.51783535,-9.397020957999999,-7.875210609,-9.837795372,-5.910335861,-1.999869568,-9.472996711730957,-11.572417259216309,-9.515859603881836,-8.93068790435791,-11.434015274047852 -374,374,G43R,-0.01653941,-1.573510556,-2.240215478,-2.4275627159999997,-2.774415405,0.005823463,0.009177201,-0.04225602,-0.13932815099999998,-1.582519915,-1.5645011969999998,-2.069216747,-2.411214208,-2.517495582,-2.33762985,-2.7881683710000003,-2.760662439,0.043870567,-1.047244703,-13.05476638,-14.41069417,-13.30337405,-13.63183779,-12.33035453,-11.59757134,-7.166468377,-4.238394326,-13.44424819946289,-16.388111114501953,-12.411020278930664,-11.728494644165039,-13.787358283996582 -375,375,G43T,-0.042480480999999994,-0.214801142,-1.5697048040000001,-2.226703123,-3.294010353,0.01581254,-0.022802656,-0.062158305999999997,-0.081870518,-0.170295825,-0.259306459,-1.4595457040000002,-1.679863904,-2.333793272,-2.1196129740000003,-3.0815873160000002,-3.50643339,1.1424382770000001,0.09507272800000001,-11.98996554,-13.17248901,-11.64800413,-12.87892946,-10.67888241,-11.57152271,-7.154128703,-4.912868137,-12.032087326049805,-15.390807151794434,-13.319475173950195,-12.081169128417969,-14.579346656799316 -376,376,G43W,-0.017646738999999998,-1.2828923970000001,-2.472765099,-2.168009471,-2.926816531,0.0464377,-0.021616775,-0.013676703,-0.091447217,-1.145597199,-1.4201875940000002,-2.7386275230000003,-2.206902675,-2.135753835,-2.200265107,-2.628275374,-3.225357687,0.5376087070000001,-0.705191738,-15.02642581,-14.361181099999998,-15.04275898,-16.04705257,-14.3695112,-15.311625199999998,-7.375283427,-3.516243648,-14.71949577331543,-17.576234817504883,-14.13615894317627,-15.50471305847168,-17.337093353271484 -377,377,G43V,-0.045673358,-1.25684123,-2.068467838,-2.51237453,-2.921696588,-0.007825116,-0.041632157999999996,-0.049714557,-0.096451403,-1.232059266,-1.281623194,-2.009475948,-2.1274597269999997,-2.14696495,-2.87778411,-2.338456494,-3.504936681,3.884151605,1.615616804,-15.79596283,-16.1755331,-16.91849915,-17.07108961,-14.5564424,-14.25824988,-9.053022883999999,-7.123456681,-12.494579315185547,-16.44188117980957,-13.584534645080566,-12.644315719604492,-14.686384201049805 -378,378,G43Y,-0.00396217,-0.968048925,-2.584198589,-2.467818316,-3.092822255,-0.036679704,0.034221808,-0.042146147,-0.055376793,-0.71168197,-1.22441588,-2.157266216,-3.011130961,-2.2533625330000002,-2.682274098,-3.0011565769999997,-3.184487933,0.9541846979999999,-0.44063281200000004,-15.93702095,-17.3521134,-16.64099828,-15.51975657,-13.93598613,-16.23625039,-8.09764078,-5.990049015,-14.291598320007324,-17.544214248657227,-14.88465404510498,-14.076971054077148,-17.810428619384766 -379,379,Y44A,-0.032056769,-0.037020995,-0.71736319,-1.9912570319999998,-2.982065641,0.065134491,-0.00799999,-0.056113548,-0.077073734,-0.063749276,-0.010292713,-0.40173626100000004,-1.0329901190000002,-1.859973752,-2.122540311,-2.528732496,-3.4353987860000004,1.582342897,0.76753041,-5.200916205,-6.367536705,-6.534333022999999,-3.1685770110000004,-4.196208145,-5.73792614,-4.030029364,1.261619069,-2.016493797302246,-5.166871070861816,-3.730764627456665,-2.4227511882781982,-7.166629791259766 -380,380,Y44C,0.005731835,-0.027246875,-0.9634012190000001,-2.117774895,-3.081494016,0.056076272,0.064422019,-0.052958349,-0.032848122,-0.025188492000000003,-0.029305257,-0.845412157,-1.081390281,-2.083577156,-2.1519726340000003,-2.788333553,-3.374654478,1.958907606,0.771965128,-7.681247687000001,-7.874620437999999,-8.790595512000001,-5.928133461,-7.69243821,-8.120450813,-6.742638616,-2.284247111,-5.153634548187256,-6.84605073928833,-5.512529373168945,-6.550204753875732,-9.409150123596191 -381,381,Y44E,-0.031477692,-0.354135011,-1.616983297,-2.625848473,-2.9701265489999997,0.08393912,0.001397176,-0.06435256,-0.020314853,-0.248172896,-0.460097126,-1.5219090419999999,-1.712057551,-2.6261804619999998,-2.6255164840000003,-2.904968127,-3.0352849710000003,1.235635815,0.093376852,-10.07004825,-10.2249962,-10.88807263,-8.534778046,-9.787725784,-10.91466857,-8.720518431,-6.437688822,-9.316473007202148,-12.924553871154785,-10.729996681213379,-7.923114776611328,-11.940756797790527 -382,382,Y44D,0.00851447,-1.465348139,-1.960738831,-2.202047407,-2.5692042280000003,0.055964627999999995,0.02364877,-0.00661983,-0.16702916199999998,-1.580020821,-1.350675457,-1.776995195,-2.144482466,-2.279206624,-2.124888189,-2.381903029,-2.7565054260000004,0.43335027600000003,-0.9775392940000001,-10.53742591,-10.31608683,-11.64558296,-8.708262283,-10.31205057,-11.705146899999999,-8.720518431,-6.437688822,-9.236345291137695,-13.397472381591797,-11.48592758178711,-10.747526168823242,-13.082014083862305 -383,383,Y44G,-0.00615611,-0.061174353,-1.161942904,-2.310945467,-3.025105581,0.059040801,0.032595772,-0.044907992,-0.065655589,-0.018007045,-0.10434166,-0.92454909,-1.399336717,-2.180428675,-2.441462259,-2.8157636630000002,-3.234447498,1.920225155,0.699607688,-9.475370552000001,-9.335515411,-10.88684491,-7.60013411,-8.74976976,-10.80458857,-7.070268662999999,-2.45768412,-4.739137172698975,-8.602741241455078,-7.105865478515625,-6.20689582824707,-10.787023544311523 -384,384,Y44F,0.041897981,0.020924838,-0.016223451,-0.0007790710000000001,-0.040809435,-0.013767383999999999,0.048343202,0.035452759,-0.010164613000000001,0.014771703999999998,0.027077971,-0.035604872999999995,0.003157972,-0.07259427,0.071036128,-0.082826713,0.0012078430000000001,1.38895447,2.334282891,-1.9301683490000001,-2.346116386,-2.2898701630000002,-1.70944101,-2.037169846,-1.268244339,-3.87037683,1.3696913730000002,-3.2236719131469727,-3.0946993827819824,-3.361171007156372,-3.901191234588623,-3.94460391998291 -385,385,Y44I,0.016883048,0.012810142,0.02749229,-0.001490999,-1.736939019,-0.0023480379999999998,0.050895873,-0.017129778000000002,-0.093440265,0.010239244,0.01538104,-0.012992684,0.06797726400000001,-0.086359831,0.083377834,-1.452297671,-2.021580367,0.947951862,1.346617629,-3.4261277010000004,-2.943506485,-2.2357930219999997,-4.714617218,-4.828631165,-2.4080906140000002,-3.6482122739999996,2.387929523,-2.5235795974731445,-5.063328742980957,-2.2411322593688965,-2.499155044555664,-4.847171783447266 -386,386,Y44H,0.040203334,-0.039072077999999996,0.007924563,-1.334261128,-2.831751718,0.074008604,0.039131736,0.041274931,-0.08105776,-0.066393272,-0.011750884,-0.041518897,0.057368023,-1.064818163,-1.6037040930000002,-2.297848337,-3.3656550989999996,0.795958919,0.75204432,-6.9893592479999995,-5.931827782,-7.976832047,-6.169763466,-7.36584169,-7.502531257999999,-7.8344044770000005,-3.864455032,-7.4063897132873535,-8.10019302368164,-7.539090156555176,-5.516709327697754,-7.856428146362305 -387,387,Y44K,-0.056311569000000006,-1.557521102,-2.2006248530000003,-2.732368775,-3.16469248,0.061873015999999996,-0.028566047999999997,-0.08405709,-0.179864649,-1.672673845,-1.442368359,-2.2120709,-2.189178805,-2.8392210660000003,-2.6255164840000003,-3.11800873,-3.21137623,0.024296011,-1.115461198,-9.736752542,-9.470126595,-10.69543957,-8.567718597,-10.05385624,-9.896621712,-8.713237982999999,-6.416687425,-10.243091583251953,-13.658843040466309,-8.475685119628906,-4.671413898468018,-12.969847679138184 -388,388,Y44M,0.042024964000000005,0.055788355,0.024222335,0.019593148,-0.283943015,0.050952017999999995,0.054180662000000004,0.029869265,-0.055681864000000005,0.030461143,0.081115566,-0.034245929,0.082690599,-0.068737256,0.10792355099999999,-0.222254788,-0.345631242,1.329867247,1.9861046690000002,-4.1835767530000005,-3.574339935,-4.386810173,-4.112641281,-4.3667755360000005,-4.477316841,-3.7628866039999997,0.27847269199999997,-2.957927703857422,-6.083809852600098,-4.659877777099609,-3.2795515060424805,-6.168209552764893 -389,389,Y44L,0.014614007,-0.020088335,-0.0046129909999999994,-0.045606460999999994,-0.24651114899999998,0.055245175,0.024009124,0.00521889,0.00594241,-0.047784756,0.007608086,-0.068293069,0.059067087000000004,-0.11132820199999999,0.02011528,-0.211479175,-0.281543123,1.580177299,2.202133025,-4.056317366,-2.6581797330000003,-5.504900871,-3.603613213,-5.5493615489999994,-2.9655314639999997,-3.2905292360000002,2.2564483109999998,-1.8396891355514526,-4.216907978057861,-2.9214978218078613,-2.464055299758911,-4.32002067565918 -390,390,Y44N,-0.077406009,-1.325477936,-1.981978275,-2.6977105889999997,-3.041988665,0.136324993,0.019294213,-0.17410623100000003,-0.16184442,-1.312239304,-1.338716567,-2.100278286,-1.8636782630000002,-2.250307196,-3.145113981,-2.8301248560000003,-3.2538524730000002,0.7872898979999999,-0.771315304,-9.665858127,-9.29325222,-10.73499046,-7.657531677000001,-9.69152581,-10.95199046,-8.720518431,-6.437688822,-8.47433090209961,-11.279387474060059,-9.289613723754883,-8.007539749145508,-11.624584197998047 -391,391,Y44Q,0.018710097,-0.672057076,-2.272106267,-2.375183941,-3.196583271,0.10302207599999999,0.041143334,-0.00372314,-0.097845943,-0.443399166,-0.900714985,-2.194256567,-2.349955967,-2.520376736,-2.229991145,-3.100194396,-3.2929721460000003,1.0043388340000001,-0.291659593,-10.05262725,-9.848283775,-11.14612659,-8.755823814,-10.58069165,-9.932210426000001,-8.720518431,-6.437688822,-8.735893249511719,-11.617191314697266,-9.10102653503418,-5.292520046234131,-10.38278579711914 -392,392,Y44P,0.026203387,-1.250192171,-2.226162408,-2.457348907,-3.027775819,0.070421711,0.050966606,0.001440167,-0.09418660400000001,-1.259382979,-1.241001362,-2.255697903,-2.1966269119999997,-2.451484304,-2.463213509,-2.730271969,-3.3252796680000003,0.578847252,-0.767887358,-10.72467361,-10.64210197,-11.66295556,-9.186104178999999,-10.39554406,-11.73666228,-8.720518431,-6.437688822,-9.603046417236328,-12.034965515136719,-8.723896026611328,-12.105229377746582,-13.490744590759277 -393,393,Y44S,-0.041875567999999995,-0.635703169,-2.002437547,-2.3173536880000003,-3.19008419,0.059412067,-0.003955683,-0.079795453,-0.006228569000000001,-0.391702759,-0.879703578,-2.040901808,-1.963973285,-2.058305153,-2.576402223,-2.6158464180000003,-3.7643219610000003,1.123315956,-0.164079843,-8.318059821,-8.327958054,-9.576047096,-5.526725151,-8.026759277,-10.13280952,-6.719616942999999,-2.5063604980000003,-5.4542012214660645,-7.475813865661621,-6.456957817077637,-5.086239814758301,-9.602043151855469 -394,394,Y44R,0.006585203,-1.275479135,-2.187369786,-2.772341373,-3.025154107,0.057826750999999996,0.035027897,-0.021857492000000003,-0.11510937800000001,-1.236736405,-1.314221865,-2.137616001,-2.23712357,-2.5886749069999997,-2.956007838,-2.809470625,-3.240837589,0.534335731,-0.737128415,-9.548428354,-9.168073212000001,-11.27351493,-8.795771126,-9.921830948,-8.582951553,-7.990917005,-3.864455032,-9.484569549560547,-11.228422164916992,-6.969989776611328,-5.65474796295166,-11.815048217773438 -395,395,Y44T,-0.01399395,-0.066186724,-1.320752277,-2.179884405,-3.195373822,0.012717504,0.020645322,-0.048633221,-0.04274268,-0.045031645,-0.08734180300000001,-1.105717908,-1.535786645,-2.13900256,-2.22076625,-2.71882022,-3.671927423,2.147963049,0.7840983,-8.034178277999999,-7.59798037,-8.88224559,-7.274069183,-8.135916557,-8.280679688,-6.15108948,-2.1478479740000003,-4.821200847625732,-7.482632637023926,-5.627524375915527,-4.292166709899902,-8.326544761657715 -396,396,Y44W,0.005107688,0.017237439,-0.127504811,-1.6054726519999998,-2.641882621,0.005950779000000001,0.038892894,-0.028677518,-0.019302853999999998,0.013024613999999999,0.021450262999999997,-0.132436891,-0.12257273,-1.376299336,-1.834645967,-2.362657177,-2.921108064,0.9783987740000001,0.744755682,-6.362318027000001,-5.899110199,-6.682725914,-5.567910034,-5.990093497999999,-7.671750488,-5.976417446,-1.8153197669999999,-4.228232383728027,-5.439976692199707,-5.206265449523926,-5.110195159912109,-7.372256278991699 -397,397,Y44V,0.014236500000000001,0.005720869,0.004887949,-0.040962159,-1.726355619,0.010963715,0.038012015,-0.009539015,-0.054385564000000004,-0.013590135,0.025031872,-0.039020877999999995,0.04879677599999999,-0.108545481,0.026621164,-1.5362221219999999,-1.916489116,0.970809488,1.341534885,-2.8672590319999998,-2.735881088,-3.6199027860000004,-3.0599272999999996,-3.667648285,-1.252935699,-2.869941874,3.738011573,-1.400484561920166,-4.351100921630859,-1.620089054107666,-1.0409889221191406,-4.488285064697266 -398,398,I45A,-0.014891277,-0.010251234,-0.0036765870000000003,0.060311952,-0.09053404599999999,-0.056741781,-0.034279223,0.004496669,-0.20493012,0.028671473,-0.049173941,0.020743258,-0.028096431,0.119841818,0.0007820860000000001,0.013013657,-0.194081748,1.285342084,2.83066336,3.326653287,3.298470413,3.066868988,3.2820297089999997,2.5221527790000002,4.463744545,0.169601665,3.435507963,-1.249011516571045,-2.204378604888916,-0.6764931082725525,-1.101850986480713,-1.097369909286499 -399,399,I45C,0.007388436,0.015949234,0.032874367,0.09476568199999999,-0.20808194800000002,0.07466110599999999,0.02001589,-0.005239018,-0.292511723,0.048737224,-0.016838756,0.053882463,0.01186627,0.128877585,0.060653778,0.017845864,-0.43400976,1.1941092229999999,2.81642152,-1.855377847,-1.227930305,-1.14993161,-0.856829185,-3.5645902019999998,-2.4776079330000003,-2.716622895,0.786985002,-3.4658524990081787,-5.283232688903809,-4.522625923156738,-4.404748916625977,-2.8615119457244873 -400,400,I45E,-0.036329991,-0.034148793999999996,-0.020492715,-1.418600532,-2.206823683,0.014938673999999999,-0.049269905,-0.023390076,-0.181041654,-0.029511614,-0.038785974,-0.00329292,-0.03769251,-1.084728433,-1.7524726309999998,-2.273341286,-2.140306079,0.8504856670000001,0.7610655609999999,-2.5166178880000003,-1.766643425,-2.830656815,-1.186383545,-3.521043648,-3.2783620069999997,-3.896640899,-0.8963184209999999,-5.455358982086182,-10.588356971740723,-7.204000473022461,-7.688559532165527,-6.688908576965332 -401,401,I45D,-0.034741945,-0.217495627,-1.702230135,-2.355596727,-2.744946474,0.018812048,-0.015416655,-0.054067234000000006,-0.1921813,-0.064772051,-0.370219203,-1.343972934,-2.060487336,-2.2500273999999996,-2.461166053,-2.60613134,-2.883761607,0.933372471,0.093055119,-4.010463385,-3.7072863160000002,-4.276267365,-2.925807854,-4.8816080930000005,-4.2613472980000004,-4.839185682,-2.202842813,-6.39943265914917,-11.588499069213867,-9.347776412963867,-8.620824813842773,-7.563797950744629 -402,402,I45G,-0.020888382,-0.01591693,-0.07062275400000001,-1.601799435,-2.210408061,-0.005257456,-0.024932955,-0.016843808999999998,-0.222332809,-0.016754189,-0.01507967,-0.010982448999999998,-0.13026305800000001,-1.32026252,-1.88333635,-2.2127476759999998,-2.208068446,0.851839074,0.734195582,-2.6290177630000002,-1.068601776,-2.1655221019999997,-1.70922319,-3.516324081,-4.685417664,-3.010405865,0.232191208,-4.709273815155029,-7.724833011627197,-6.05527400970459,-6.229048728942871,-4.829862117767334 -403,403,I45F,0.036822897,0.051928422,0.050583595999999995,0.12096271800000001,0.139663466,-0.04017073,0.028710773,0.04493502,-0.24342621600000003,0.062187604,0.04166924,0.09560276699999999,0.005564425,0.21213025,0.029795185,0.21619534399999998,0.063131587,0.9142746409999999,3.018596392,-0.14109949,0.109815613,-0.628009018,0.562375031,-1.658426971,0.9087478940000001,-2.1298192240000002,2.489877843,-3.170666217803955,-6.538980484008789,-2.393540620803833,-2.2950785160064697,-3.735807418823242 -404,404,I45H,-0.045660262,-0.011967566,-0.020381376,-0.646046104,-2.169112095,-0.038642684,-0.037582444,-0.053738079,-0.22710956,0.018236766,-0.042171898,-0.005057862,-0.035704889,-0.372596983,-0.919495224,-2.026096634,-2.312127555,1.4950265740000002,1.347648512,-1.219146098,-0.9963319629999999,-1.111905502,-0.589825798,-1.88270372,-1.514963509,-2.31242183,2.063681437,-4.178543567657471,-8.86402416229248,-4.150308609008789,-4.5851569175720215,-4.345512390136719 -405,405,I45K,-0.018968267,-0.39921294399999996,-1.705642668,-2.296539891,-2.9473290110000003,-0.06968419099999999,-0.04155759999999999,0.0036210659999999996,-0.189465828,-0.22155815399999998,-0.576867734,-1.606712004,-1.804573332,-2.132555228,-2.460524554,-2.789689164,-3.1049688580000003,1.420247118,0.118345787,-3.8838373280000003,-3.301928169,-5.146250061,-2.907959015,-4.79464463,-3.268404762,-5.259645741,-2.333509679,-7.584731578826904,-9.57801628112793,-7.998215198516846,-6.812400817871094,-9.334922790527344 -406,406,I45M,-0.004667943,0.018591503,0.007400829,0.06067423,-0.361981496,-0.051515730999999995,-0.00737908,-0.001956806,-0.20094993600000002,0.026662312,0.010520693000000001,-0.022317807000000002,0.037119465,0.10172946,0.019619,-0.17908827800000002,-0.544874714,1.252387475,2.081072839,-0.29936656300000003,-0.213972931,-1.37041983,0.296932594,-1.24780616,1.03843351,-2.962662043,-0.083641429,-4.640249252319336,-6.065629482269287,-4.23017692565918,-3.9419870376586914,-4.288000583648682 -407,407,I45L,0.031797042000000005,-0.005337476999999999,0.021407197000000003,0.07363445099999999,0.108687949,-0.036477322,0.018342041,0.045252042,-0.196976609,-0.000759542,-0.009915410999999999,0.044821819000000006,-0.002007425,0.13535979,0.011909111000000002,0.226670178,-0.00929428,0.945439444,3.1116413119999997,-0.0069666630000000005,0.673880844,-0.9098845520000001,1.048926575,0.14503633900000001,-0.9927925190000001,-2.7274268839999998,1.589487343,-2.68315052986145,-5.425897598266602,-3.443129062652588,-2.68078875541687,-3.534475326538086 -408,408,I45N,-0.012980671000000001,0.018068827,-0.319156277,-1.6807976180000002,-2.632616734,0.054159132,-0.016617431000000002,-0.009343911,-0.254805187,0.047780511,-0.011642858,-0.200784378,-0.437528176,-1.544523359,-1.8170718769999998,-2.50268729,-2.762546177,1.2013852170000001,0.75273817,-3.3396847380000003,-3.2541949389999996,-3.997139877,-2.594777939,-4.193219421,-2.659091515,-4.583091233999999,-1.935760123,-5.474203109741211,-9.893699645996094,-7.887058734893799,-7.2624053955078125,-6.303861141204834 -409,409,I45Q,0.000276368,-0.018293848999999997,-0.032400378,-0.04257319,-1.581182994,-0.073691823,0.003110448,-0.002557712,-0.17897961,-0.005650598000000001,-0.0309371,-0.012043273,-0.052757483,0.045161589,-0.130307968,-1.50525843,-1.657107558,0.619138335,1.316428965,-1.760384074,-1.334345718,-2.420620621,-1.102562531,-1.914016434,-2.030375069,-3.500349739,-0.649267586,-4.738277435302734,-9.790271759033203,-5.688408374786377,-6.214539527893066,-5.690285682678223 -410,410,I45P,-0.032289778,-1.48602847,-2.227593906,-2.265296022,-2.896751736,-0.017779745,-0.029995638999999998,-0.034583916,-0.32057431399999997,-1.4651576469999998,-1.506899293,-2.134701358,-2.320486454,-2.227842467,-2.302749576,-2.74364725,-3.049856222,1.792513122,-0.5356174810000001,-4.94666398,-4.272957031,-5.355366127,-4.1307752760000005,-5.78031295,-5.1939085160000005,-6.866717857,-5.589167355,-9.342657089233398,-13.110544204711914,-11.058812141418457,-11.23002815246582,-10.297582626342773 -411,411,I45S,-0.041614227000000004,-0.01125545,-0.001442758,0.061595782,-1.494600621,-0.011318352,-0.063262464,-0.019965989,-0.22620821,0.033593582999999996,-0.056104482000000004,0.018881702,-0.021767217000000002,0.10027640800000001,0.022915155,-1.364972001,-1.6242292409999999,0.56597735,1.318579774,1.669666541,1.7485426480000001,1.756723038,1.819228676,0.36859000399999997,2.6552483369999997,-1.295651665,2.374909329,-2.6123971939086914,-4.31149435043335,-3.3612146377563477,-4.014230728149414,-2.8168673515319824 -412,412,I45R,-0.044948252,-0.037685244,-0.24089141100000003,-1.657245813,-2.60881519,-0.0037643359999999996,-0.043349719,-0.046546785,-0.233237845,-0.020200821,-0.055169666,-0.10131343400000001,-0.38046938700000005,-1.402827007,-1.911664618,-2.0180687809999998,-3.1995615980000003,2.7947938789999998,1.889843638,-3.019039293,-2.85657653,-3.2746641010000004,-2.265980095,-3.4469306339999997,-3.251045105,-4.2600426360000005,-0.501861679,-7.044345855712891,-9.162698745727539,-7.093883037567139,-5.85087776184082,-8.681098937988281 -413,413,I45T,-0.041662465,-0.053740798,-0.034064788,0.025185182999999996,-0.426357269,-0.09068389800000001,-0.063211104,-0.020113825,-0.205277131,-0.02276543,-0.084716166,-0.013306181,-0.054823394000000004,0.07156475400000001,-0.021194388999999998,-0.260009143,-0.592705394,0.9315990470000001,1.694327196,1.7490607530000002,1.5317357180000002,1.4812826769999998,1.705367249,0.835747337,3.1911707839999996,-0.817092127,0.9670311840000001,-2.7568817138671875,-4.701799392700195,-3.838474750518799,-4.591953277587891,-3.6849961280822754 -414,414,I45W,-0.05570905,-0.088478575,-1.1840278,-2.140760722,-2.9109908860000004,-0.016762281,-0.072527172,-0.038890928,-0.213213255,0.017485675,-0.194442825,-1.046992535,-1.321063065,-1.699441655,-2.582079788,-2.993397688,-2.8285840839999996,2.4094699090000002,1.114131465,-3.205490727,-2.105722733,-4.057880668999999,-1.318829796,-3.7960662989999996,-4.74895414,-3.2306559939999997,0.430730935,-6.152822494506836,-10.464591979980469,-5.038577556610107,-5.22963285446167,-6.909768104553223 -415,415,I45V,-0.004989384,-0.04281224,-0.032864557999999995,0.035339036000000004,0.12200949,-0.04214383,-0.020172717,0.010193949,-0.139570265,-0.030712117999999997,-0.054912362,-0.007965682,-0.057763432999999996,0.09887483300000001,-0.028196762,0.190229713,0.053789267,1.543610422,3.106887046,1.784145535,1.918226631,1.30478952,1.898335976,1.39562162,2.403753929,-0.609537134,1.719377433,-1.7691268920898438,-2.5542545318603516,-1.4154925346374512,-2.037696361541748,-2.5572991371154785 -416,416,I45Y,0.031627791,0.011890158999999999,0.058367113,0.10621945,-0.198298791,-0.041183062,0.050049058,0.013206523999999999,-0.257583044,0.021708434,0.002071883,0.052640083,0.064094142,0.144879153,0.06755974599999999,0.015638868,-0.41223645,1.1060094409999999,2.723212628,-0.308281503,-0.6998122859999999,-0.7674776,0.313041862,-1.865627411,1.4784679180000002,-1.454455146,3.3589984989999997,-3.0164613723754883,-7.048226356506348,-1.663179874420166,-2.0079362392425537,-3.4690499305725098 -417,417,E46A,0.06054994,0.050636307,0.030166752,0.085523852,-0.05797503,0.013691409,0.091959717,0.029140162,0.154220461,0.099576909,0.001695705,-0.017796108,0.078129611,0.0461185,0.124929204,-0.111100066,-0.004849994,1.229407927,2.219399137,-3.808890753,-5.366256149,-3.003720993,-4.174555626,-4.262225418,-2.23769558,-3.642318775,4.487299911,-3.1475796699523926,-6.745126724243164,-4.423830032348633,-4.598862648010254,-2.5158355236053467 -418,418,E46C,-0.056629725,0.025298822999999998,-0.009662677,-0.22259505,-1.899140071,0.010692466000000001,-0.030418266,-0.082841184,0.012697907,0.08683486900000001,-0.036237224,0.00360007,-0.022925424,-0.07711414700000001,-0.36807595299999996,-1.8452071780000001,-1.953072964,0.957874186,1.315371901,-8.587476062,-8.806901161,-6.602233582,-10.14982264,-7.989672722000001,-9.388750206000001,-5.914546283,0.202951675,-6.573666572570801,-10.320487022399902,-9.403210639953613,-10.45765495300293,-8.78870677947998 -419,419,E46D,-0.034026852,0.077207259,-0.01121432,0.066829216,-1.243973026,0.070207849,-0.0019518889999999998,-0.066101815,0.07087382099999999,0.120517982,0.033896536,0.001117862,-0.023546502,0.08425423800000001,0.049404193,-0.947091228,-1.540854824,0.18103532,1.315883854,-6.28407231,-6.306083374,-5.355953209,-5.749550033999999,-6.326615189,-7.682159744,-8.707703472999999,-5.014427893,-2.9217844009399414,-7.979416847229004,-6.050774574279785,-2.9117627143859863,-7.0392069816589355 -420,420,E46G,-0.0716871,0.022127314,-0.033731841,-0.112749622,-1.769257835,0.047312572000000004,-0.044943791,-0.09843040900000001,0.045381452,0.032843258,0.011411369,-0.015423167,-0.052040515,-0.080134065,-0.145365178,-1.837995065,-1.700520604,0.870913354,1.312266635,-7.88550468,-8.498576492,-6.768200195,-7.905658371,-6.715464317,-9.539624023,-5.151778062,1.027239873,-5.793247222900391,-7.749049186706543,-6.887702465057373,-6.134187698364258,-5.873034477233887 -421,421,E46F,0.056858217999999995,0.012120928999999999,-0.005820929,0.09162494199999999,-1.180487928,-0.033962325,0.078717836,0.034998599,0.019894801,0.026016262000000002,-0.001774405,-0.034663114,0.023021257000000003,0.06675508200000001,0.116494801,-0.801037275,-1.559938581,0.479584795,1.346875254,-7.66766398,-6.2973042910000006,-6.980595253,-9.270146217,-7.842499022999999,-7.947775116,-5.086982256000001,2.794745494,-6.379282474517822,-11.737260818481445,-8.381009101867676,-9.236021041870117,-7.4054975509643555 -422,422,E46I,0.017371427,0.071263735,0.04403818599999999,0.074960336,-0.6382741820000001,0.0005886940000000001,0.011841646,0.022901208,0.01318001,0.098159972,0.044367498,0.053893439,0.034182932,0.057686429000000004,0.092234242,-0.5555714629999999,-0.7209769009999999,0.498235184,1.37936072,-4.231761859,-3.4725048289999996,-4.839422783,-3.748002609,-2.647958649,-6.450920425,-2.773764012,3.5552320319999997,-4.880959987640381,-9.471782684326172,-6.905425548553467,-7.876035690307617,-4.495562553405762 -423,423,E46H,0.016038643,0.038763722,-0.004284774,0.070566517,-0.84199284,-0.010645621000000001,0.064702105,-0.03262482,0.020417451,0.07613890400000001,0.001388539,0.002980277,-0.011549823999999998,0.059088533,0.0820445,-0.619399754,-1.064585926,0.667201688,1.403997961,-9.856631718,-9.940475021000001,-7.892904518,-11.24007329,-11.11778837,-9.091917397000001,-7.612027349,-2.585164641,-6.67496919631958,-10.690244674682617,-7.228931903839111,-7.17449426651001,-8.98125171661377 -424,424,E46K,-0.04262828900000001,0.009826356,-0.028252494,0.05020906,-0.22417449899999997,0.053422087,-0.029650105,-0.055606473,0.004697474,0.086771448,-0.067118736,0.000339186,-0.056844173,0.07971924,0.020698879,-0.18200102199999998,-0.26634797600000004,1.230778489,2.044033568,-7.983046542,-8.664197655,-6.375084496,-8.858606712,-7.35169342,-8.665650429,-8.665464397000001,-4.892439621,-7.790119647979736,-10.824310302734375,-7.591099739074707,-9.140131950378418,-8.88306999206543 -425,425,E46M,0.036580697,0.059989659,-0.000607231,0.050199035,-0.019380393,0.00388934,0.035434777,0.037726616,0.063261867,0.13963688,-0.019657562,-0.00344187,0.002227409,0.022660612000000004,0.077737458,-0.01826552,-0.020495266,1.1590993840000001,2.464796203,-5.721038084,-4.642255157,-6.406587486,-6.820715187,-4.474703208999999,-6.2609293820000005,-3.5219039010000004,1.457089605,-5.317016124725342,-9.61649227142334,-7.6502275466918945,-8.358640670776367,-5.155861854553223 -426,426,E46L,-0.00807517,0.047658725,-0.002553821,0.052847915999999995,-0.114128551,-0.019832737,-0.00376702,-0.01238332,0.057383958,0.08846176900000001,0.006855681,0.001565629,-0.006673271,0.05677958,0.048916250999999994,-0.115979851,-0.112277251,1.2430237370000001,2.18724123,-4.538006567,-3.394428352,-6.556716064,-4.450208595,-3.1138764039999995,-5.174803421,-3.215730677,3.086687004,-4.131458759307861,-9.049830436706543,-5.929971694946289,-7.437379837036133,-4.886376857757568 -427,427,E46N,-0.009217056,0.05041252,-0.023756553,0.05014026,0.002957374,0.044187715999999995,0.011812086999999999,-0.030246198,0.054513575999999994,0.10628193,-0.00545689,-0.019917459,-0.027595646,0.074618377,0.025662142000000002,-0.048247827,0.054162574000000005,1.231905283,2.494125114,-8.82970883,-8.282891525,-7.528516487,-9.21359021,-8.987594482,-10.13595145,-8.707703472999999,-5.014427865,-6.382843017578125,-10.93366813659668,-7.987923622131348,-7.334915637969971,-7.979066371917725 -428,428,E46Q,-3.929999999999999e-05,0.018893436,-0.052478897000000004,0.040676305,0.013281701000000002,-0.018003293,-0.000370539,0.000291882,0.054529875,0.04139076,-0.0036038890000000003,-0.059334277000000005,-0.045623515999999996,0.025962124,0.055390485999999996,-0.021479919,0.04804332,1.2008836840000001,2.47469079,-4.7087223719999995,-4.221145706000001,-5.062656723,-5.104541771,-3.656731575,-5.498536087000001,-6.397644746,-1.9150143069999999,-5.690900802612305,-7.086119651794434,-5.159698486328125,-7.017590522766113,-6.114457607269287 -429,429,E46P,-0.052235465,-1.334710467,-2.157057672,-2.115757725,-2.526018257,0.024315688,-0.030253078,-0.074217852,-0.018536113,-1.321607612,-1.3478133209999998,-2.367930328,-1.946185015,-1.9740178080000002,-2.2574976419999997,-2.445535185,-2.606501329,0.17574834,-0.823624142,-10.38930708,-10.62341103,-9.37322773,-11.79142071,-10.06058698,-10.09788898,-8.513403621,-4.228818024,-10.230916976928711,-13.060026168823242,-7.316960334777832,-11.99305534362793,-10.373035430908203 -430,430,E46S,-0.019238599,0.00025504200000000003,-0.028739924,0.057902964,-0.006555508000000001,0.038353476000000004,-0.01855298,-0.019924218,0.038079569,0.031720898,-0.031210815,-0.025830129,-0.031649718,0.043292607000000004,0.07251332099999999,-0.004788786,-0.008322229,1.153119917,2.483269178,-7.783836906,-8.225326767,-5.116671913,-9.389224083,-7.452924423,-8.735037346,-6.279417779,-0.664948268,-4.182565689086914,-7.744065761566162,-5.47014045715332,-6.721704006195068,-4.771098613739014 -431,431,E46R,-0.054496014,0.017555477,-0.015553218,-1.238927817,-2.305126814,0.036406638,-0.034105339,-0.074886689,-0.012558231999999999,0.066399326,-0.031288372,-0.017221723,-0.013884713,-0.665080744,-1.81277489,-1.869896154,-2.740357473,1.826191017,1.446219353,-8.536732475,-9.519359489,-7.328752586,-9.701802528,-8.304648407,-7.829099365,-6.68473156,-1.5227881319999998,-7.684041976928711,-11.020495414733887,-7.046067237854004,-9.438899993896484,-9.211984634399414 -432,432,E46T,-0.03691943,0.018746185,-0.054674957999999996,0.040899157,-0.119318986,0.021289178,-0.031073002000000002,-0.042765858,0.103225619,0.062409485,-0.024917116,-0.022000142,-0.087349774,0.051597051,0.030201262000000003,-0.132083344,-0.10655462800000001,1.4371960190000002,2.35126766,-7.207790398999999,-8.462076309,-5.750165947,-7.075709122,-6.700850449,-8.050150169,-5.808738174,-0.236334988,-5.0488505363464355,-8.090760231018066,-6.422937393188477,-7.132587432861328,-4.550861358642578 -433,433,E46W,-0.025455624,0.053528052,-0.002827434,-1.371179138,-2.2824983309999998,0.024918929,0.002392595,-0.053303843,0.035329843,0.060204085,0.046852017999999995,0.0077124540000000005,-0.013367322,-0.917954226,-1.82440405,-2.159797516,-2.4051991459999997,1.98631072,1.3937407569999998,-9.813522336,-9.799028801,-9.46931176,-11.09954016,-8.457481162999999,-10.24224979,-6.396960907,-0.5495289560000001,-7.291496753692627,-12.545404434204102,-9.759519577026367,-10.510029792785645,-9.942239761352539 -434,434,E46V,-0.026138446,0.011802706999999999,-0.021033887999999997,0.047510002,-0.37781022200000003,-0.018590215,-0.018086215,-0.034190676,0.041749152000000005,0.070934786,-0.047329372,-0.021033095,-0.021034681,0.030835808,0.064184196,-0.286296736,-0.46932370700000003,1.359013494,1.9596026119999999,-3.073412158,-3.5394050060000004,-2.898226036,-3.6137048189999996,-2.234872971,-3.080851959,-3.03236904,4.380493027,-3.727518320083618,-7.806610584259033,-5.29854679107666,-6.098520278930664,-2.752861261367798 -435,435,E46Y,-0.015178575,0.018257015,-0.036370772999999995,0.039721939,-1.06271258,-0.011632763,0.006914764,-0.037271913999999996,0.044365529,0.114175661,-0.077661631,0.0015099129999999999,-0.074251459,0.051543201,0.027900676,-0.806396308,-1.319028851,0.603182376,1.366965919,-8.818946312000001,-8.502829536,-6.69534977,-10.6518856,-8.947990135,-9.296676521,-5.901327855,1.664637617,-6.122119426727295,-11.589850425720215,-8.331459045410156,-8.4675931930542,-8.11707592010498 -436,436,L47A,-0.051059291,0.003596347,-0.012033631000000001,0.00308627,-0.587413548,0.076982759,-0.074931998,-0.027186582999999997,-0.005942553000000001,0.019082994,-0.011890301,0.009476974,-0.033544235,0.017717286000000002,-0.011544747,-0.38660588700000004,-0.788221209,0.869335544,1.557849448,-5.976561972000001,-5.868159508,-6.0610713579999995,-6.23526918,-6.835502067999999,-4.882807747,-4.226155507,-2.330969833,-6.23015022277832,-7.417862892150879,-6.9112982749938965,-6.669285774230957,-6.378934860229492 -437,437,L47C,-0.17789538300000002,-0.010264684,-0.037005878,-0.053354012,-1.7207472680000002,0.054898685999999995,-0.18166569,-0.17412507600000002,0.026060853,0.10352193300000001,-0.12405129999999999,0.049881302999999995,-0.12389305800000001,0.091714584,-0.198422608,-1.332143453,-2.109351082,0.609765311,1.323823782,-6.961350917000001,-6.905696136,-6.733259422000001,-6.973345413,-8.270936897,-5.923516716,-5.22799321,-3.692537488,-8.706127166748047,-9.413067817687988,-9.454310417175293,-7.862342357635498,-9.557821273803711 -438,438,L47E,-0.013553505,0.035271324,0.0044990379999999995,-0.39042400200000005,-1.741683954,0.083603992,0.023627269,-0.050734278,0.0047279620000000005,0.006651574,0.063891074,0.004701454,0.004296622,-0.068516258,-0.7123317459999999,-1.5947517130000002,-1.8886161940000001,0.8047808870000001,1.324518555,-5.441822897000001,-6.168141296,-5.322952377,-5.7028271639999994,-7.913175926,-2.1020177230000003,-3.3567426019999997,-1.3200946279999999,-6.398140907287598,-9.372807502746582,-6.447352886199951,-8.636577606201172,-5.407499313354492 -439,439,L47D,-0.051868795,-0.213851309,-1.4478525119999999,-2.276927975,-2.5184671130000003,0.073470414,-0.064013779,-0.039723811,0.008954258,-0.107920204,-0.319782413,-1.233587675,-1.6621173480000002,-2.469639117,-2.084216833,-2.271598702,-2.7653355239999997,0.974016088,0.117022543,-8.13867099,-8.341438065,-8.463430618,-8.373262749,-8.645823456,-6.869400063,-7.035237185,-3.91987831,-8.387661933898926,-11.54529857635498,-9.54051685333252,-10.57674789428711,-8.159384727478027 -440,440,L47G,-0.11137873400000001,0.013844163999999999,-0.087146852,-1.6614188109999999,-2.8146950630000003,0.09469222199999999,-0.081204666,-0.141552802,-0.049342564000000005,0.036530436,-0.008842108000000001,0.022069126,-0.196362829,-1.4155797680000002,-1.9072578530000002,-2.484711081,-3.1446790439999996,0.816678433,0.7204311040000001,-6.813700732,-7.064935921,-6.404118187000001,-7.757251274,-7.1255508579999995,-5.7166474229999995,-5.105666458,-2.971218,-8.97871208190918,-11.609627723693848,-10.573081970214844,-10.592536926269531,-8.496252059936523 -441,441,L47F,-0.111915134,0.02702744,-0.005378514,-0.034650598,-1.674340022,0.000251126,-0.124618205,-0.09921206199999999,-0.071283237,0.032419184,0.021635695,0.046623987,-0.057381015,0.000498635,-0.06979983099999999,-1.35274265,-1.9959373930000002,0.768567621,1.335126229,-4.025596591,-3.3302421719999997,-3.85523616,-3.148200089,-6.193979256,-3.6003252789999998,-3.280946487,-2.371572923,-6.409525394439697,-6.9678826332092285,-5.511417388916016,-6.632852554321289,-6.37299108505249 -442,442,L47I,-0.00042362,-0.036014443,0.001604926,0.009014886,0.024688881,0.048821878,-0.006509568,0.005662329,-0.014162802,-0.017844302,-0.054184584,0.036526353,-0.033316502000000005,0.064395316,-0.046365545,0.08634447199999999,-0.03696671,1.06323227,2.75959641,-1.987486255,-1.6387163009999999,-2.675816452,-2.777168381,-1.885587334,-0.960142807,-2.9525854689999997,-0.535826644,-4.76166296005249,-3.9486589431762695,-3.0192317962646484,-4.929001808166504,-4.5627946853637695 -443,443,L47H,-0.042535027999999996,0.0034903829999999997,-0.029723903,-1.6432079430000002,-2.394776979,0.03861328,-0.059628997,-0.025441059,0.009260621,0.005599929,0.001380836,0.008416475,-0.067864281,-1.419520492,-1.8668953940000002,-2.476752583,-2.312801374,0.579052138,0.699429082,-4.68906608,-4.306247032,-5.058229225,-5.801630219,-4.84699823,-3.432225693,-3.658150931,-1.851189409,-7.025735378265381,-8.824201583862305,-6.67219877243042,-6.808873653411865,-6.837409496307373 -444,444,L47K,-0.09857844199999999,0.012938495,-0.033523903,-1.01202238,-2.002716795,0.08713804900000001,-0.064378005,-0.13277887800000002,-0.014665225,0.00739597,0.018481018999999998,-0.032426362,-0.034621444,-0.639665653,-1.3843791069999998,-2.057049191,-1.948384399,1.821381855,1.395874941,-5.093168765,-6.037705551,-4.468633415,-7.533616829,-4.685288727,-2.740599304,-5.1023377530000005,-0.8544726290000001,-8.130594253540039,-10.299527168273926,-7.715775012969971,-9.135401725769043,-6.545350551605225 -445,445,L47M,-0.030054335,-0.017289793,0.0012028339999999998,-0.00286302,0.013633703,0.00604344,-0.035179454,-0.024929216,0.031437411,-0.049824081,0.015244496000000001,0.010151387,-0.00774572,-0.003699317,-0.0020267220000000003,0.0032150670000000003,0.024052338,1.164682365,2.593359679,-2.866801642,-2.748287895,-3.6031698530000003,-3.127994614,-3.166368416,-1.688187431,-3.247831352,-2.293250483,-5.578101634979248,-7.176339149475098,-4.2625908851623535,-6.545804023742676,-4.959461688995361 -446,446,L47N,-0.10600271900000001,0.050773665999999995,-0.49401955,-1.9640183530000002,-2.469694379,0.082073102,-0.061264769000000004,-0.150740669,-0.056874042,0.03313762,0.068409711,-0.340682615,-0.647356484,-1.6224915469999999,-2.305545158,-2.253754905,-2.685633853,1.638452059,0.856767042,-6.8411724529999995,-7.262988686,-7.265125122000001,-8.115511696,-5.641012093,-5.92122467,-5.970605431,-3.9397398260000003,-7.518433570861816,-10.623261451721191,-9.244656562805176,-8.895846366882324,-7.873317718505859 -447,447,L47Q,-0.038064366,0.008879526,-0.022764916,-0.044110424,-0.861640165,0.061419611,-0.071354488,-0.004774243,0.048251261,0.050343976,-0.032584924,0.008605251,-0.054135083,-0.033860878999999997,-0.054359968,-0.535073305,-1.188207025,0.896020182,1.48144071,-4.868536902,-5.512807648,-5.182126038,-5.85766468,-5.084257759,-2.7058283839999997,-3.488338919,-1.956936241,-5.977713584899902,-7.998603820800781,-6.113038063049316,-7.211474895477295,-4.56337308883667 -448,448,L47P,-0.054203062,-1.385023975,-2.214168575,-2.314785103,-2.8388624539999996,0.08760109,-0.038753876,-0.069652247,-0.10422844099999999,-1.399029979,-1.371017971,-2.069727387,-2.358609762,-2.104133465,-2.525436741,-2.635026278,-3.04269863,-0.016062728000000002,-0.877195519,-9.009735564,-7.181129837,-9.440281127999999,-10.50915026,-10.43709023,-7.48102636,-6.369178056,-4.931618285,-10.776668548583984,-12.733491897583008,-10.42376708984375,-10.865108489990234,-10.20635986328125 -449,449,L47S,-0.07002549799999999,-0.007096858,-0.018456814,-0.020467224,-1.746007831,0.069372182,-0.043688385999999996,-0.096362609,0.000648872,-0.000262822,-0.013930894,-0.003107562,-0.033806065,0.041012808,-0.081947256,-1.5593872340000001,-1.9326284280000001,0.637336306,1.315348132,-5.659641037,-5.75806395,-5.736384682000001,-6.606531242000001,-5.3315012589999995,-4.865724052,-4.761124145,-2.479968139,-7.099870204925537,-9.36921501159668,-7.744769096374512,-7.998861789703369,-7.1526288986206055 -450,450,L47R,-0.080554719,0.016674459,-0.18297436600000003,-1.659239406,-2.5072716369999997,0.061273978,-0.064869001,-0.096240436,-0.068280453,0.021681214,0.011667704,-0.036211181,-0.329737551,-1.3536954209999998,-1.9647833909999999,-2.103823368,-2.910719905,2.39919235,1.532607764,-3.940149925,-4.592226341,-4.209646461,-4.16333889,-4.3777554169999995,-2.357782516,-3.321682584,-0.513203665,-7.648698806762695,-9.18245792388916,-7.685188293457031,-7.902172088623047,-6.26990270614624 -451,451,L47T,-0.040328411,-0.001473683,-0.035655427999999996,-0.02291643,-0.895189117,0.039661032,-0.040082386,-0.040574435,-0.007180999,0.00091807,-0.003865435,-0.019970855,-0.051340000999999996,-0.001897201,-0.043935657999999995,-0.597162906,-1.193215327,0.832025127,1.4515295019999999,-4.773603612,-5.008584503,-5.836343948,-5.590960892000001,-4.046418098,-3.385710617,-3.9306475780000003,-2.043393015,-6.269280910491943,-8.096609115600586,-6.139432907104492,-6.189017295837402,-5.891722679138184 -452,452,L47W,-0.054333674000000005,0.045842021,-0.033833415,-1.5498587240000001,-2.8026120480000003,0.115609702,-0.016967924,-0.091699424,-0.060595526,0.022970461,0.06871358,-0.00033124099999999997,-0.067335589,-1.187807583,-1.911909865,-2.8982521869999998,-2.706971909,0.526928949,0.7173101040000001,-5.462041212000001,-5.495563622000001,-5.76848262,-4.908272636,-7.233802811,-3.9040843730000003,-3.665933172,-2.603674053,-9.004672050476074,-9.798864364624023,-8.801374435424805,-10.093927383422852,-8.330594062805176 -453,453,L47V,-0.039439073,0.017396459,-0.0026445809999999996,-0.018979753999999998,0.021797609,0.038118534,-0.061533559,-0.017344586000000002,0.04983869900000001,-0.012132021000000002,0.046924939000000006,-0.015472548000000001,0.010183387,-0.023450807999999997,-0.014508699,0.037644221,0.0059509969999999995,1.2219932820000001,2.781093991,-2.6022340330000002,-1.823110016,-3.7686521839999996,-2.462959427,-3.0539708560000003,-1.9024776840000002,-2.582547569,-0.576204739,-5.14616584777832,-5.127925395965576,-4.055121898651123,-4.416365623474121,-4.880506992340088 -454,454,L47Y,-0.063003098,0.01177264,-0.034851602,-0.020247827,-1.5723758980000002,0.054430947,-0.065430788,-0.060575408,-0.024064245,-0.061443837,0.08498911599999999,-0.057805878,-0.011897325,-0.005874305,-0.034621348999999996,-1.320531299,-1.8242204969999998,0.684650148,1.329924508,-3.9779014569999998,-3.512618256,-4.548266525,-4.123055901,-4.419074287,-3.286492317,-3.753863403,-1.9160399609999998,-6.626217842102051,-8.144355773925781,-6.000229358673096,-6.642524242401123,-7.21740198135376 -455,455,D48A,-0.021167461000000002,-0.026105557999999997,-0.028627866000000002,-0.062238362,-1.202840841,0.020056556,-0.041043251,-0.00129167,0.0041560979999999996,-0.04063843,-0.011572686,-0.041359501,-0.015896231,-0.13548058300000002,0.01100386,-0.887827921,-1.517853761,1.2484802940000002,1.5070412569999998,-5.435668627999999,-6.135788757,-4.829159439,-3.4052073210000002,-6.794312851,-6.013874771,-4.986498452,-3.1735882330000003,-9.642353057861328,-9.267328262329102,-9.067797660827637,-9.311605453491211,-9.699006080627441 -456,456,D48C,-0.065482569,0.004249118,0.012368206999999999,-0.138810352,-1.743934184,0.007393545,-0.095325718,-0.03563942,-0.062289300000000006,0.050359372,-0.041861136,0.0016393820000000002,0.023097031,-0.103963276,-0.173657428,-1.660553224,-1.8273151440000002,0.790422107,1.317627204,-8.630035666,-10.01272017,-9.23981955,-7.0369434360000005,-9.809575378,-7.051119797,-6.501858519,-4.630611443,-11.22642707824707,-9.481332778930664,-11.830358505249023,-10.265859603881836,-12.44781494140625 -457,457,D48E,-0.030880974,-0.040698727000000004,-0.051885564,-0.084194609,-0.12991054,0.010224333,-0.053756930999999994,-0.008005017,0.009852059,-0.061937503,-0.01945995,-0.054017199,-0.049753927999999996,-0.118524125,-0.049865092,-0.118060601,-0.141760478,1.450597315,2.2655999159999998,-3.990808118,-4.337031647,-3.8632069319999998,-2.7406567,-5.405126632999999,-3.608018677,-3.9025589760000003,-2.9804423260000004,-7.2772064208984375,-6.746939659118652,-7.375371932983398,-6.797402858734131,-8.179276466369629 -458,458,D48G,-0.11553479900000001,-0.079927229,-0.081447123,-0.082869369,-1.782656107,0.026251116,-0.122287467,-0.10878213099999999,0.002043347,-0.081035853,-0.078818604,-0.10049717,-0.062397075,-0.092794864,-0.072943874,-1.6733295209999999,-1.8919826919999998,1.080125408,1.3404552859999999,-6.822611116,-7.633766372999999,-4.67491539,-5.618289093,-9.188933449,-6.997151276,-5.414938788,-3.0633433389999998,-9.273914337158203,-9.849952697753906,-9.880943298339844,-9.937603950500488,-9.723933219909668 -459,459,D48F,-0.120341789,-0.114151758,-0.270411348,-1.7294805309999999,-2.502426189,0.0109794,-0.15194222599999999,-0.088741351,-0.075662201,-0.030892282000000004,-0.197411234,-0.12023012300000001,-0.42059257200000005,-1.6964719080000001,-1.762489154,-2.419244827,-2.58560755,0.9058990020000001,0.700271235,-10.08087168,-11.81749217,-12.08206539,-8.334009338,-10.76854854,-7.402242966,-7.557286639,-5.774254865,-12.242729187011719,-11.850435256958008,-12.061973571777344,-12.732634544372559,-13.265899658203125 -460,460,D48I,-0.114177686,-0.051062237,0.010006417,-1.373383494,-2.340419237,-0.045748225,-0.162597926,-0.065757445,0.008418743000000001,-0.015652316,-0.086472157,-0.017302076,0.03731491,-1.132200478,-1.61456651,-2.118214831,-2.5626236430000002,2.2737298999999997,1.506362465,-8.876586653,-11.07857143,-10.74715301,-7.381396400000001,-9.74418438,-5.431628052000001,-6.271883715,-5.225569267,-12.208693504333496,-10.639963150024414,-10.724844932556152,-11.874195098876953,-12.327554702758789 -461,461,D48H,-0.235753333,-0.08268299900000001,-0.144521035,-0.203239903,-1.852532013,-0.036863981000000004,-0.176050569,-0.295456096,0.05318096,-0.031602494,-0.133763504,-0.034567768,-0.254474301,-0.092900669,-0.31357913600000004,-1.4404767059999999,-2.264587319,1.177891237,1.3800280230000002,-5.380125072999999,-7.854518204,-7.348927413999999,-2.584703094,-5.460810562000001,-3.6516660919999997,-4.750180347,-2.360048297,-9.699614524841309,-8.857417106628418,-8.625117301940918,-8.816707611083984,-10.253946304321289 -462,462,D48K,-0.0024798579999999997,-0.045512168,-0.06520930000000001,-1.559207861,-2.633183513,-0.023727654,0.043077291,-0.048037007,0.086251945,-0.040656526,-0.05036781,-0.11311777199999999,-0.017300827,-1.5984053180000002,-1.5200104030000001,-2.446116973,-2.820250053,1.00722918,0.722007831,-8.182988864,-9.002752525,-10.04325862,-5.232564117,-9.26144902,-7.374920036000001,-6.582040207,-5.29313656,-12.449236869812012,-11.641390800476074,-10.605095863342285,-10.826173782348633,-12.018957138061523 -463,463,D48M,-0.105161954,-0.121135801,-0.086154034,-0.250932596,-2.264804231,0.011928709,-0.133982868,-0.076341039,-0.006974205,-0.141581565,-0.100690036,-0.073845255,-0.09846281300000001,-0.250153093,-0.25171209899999997,-1.947371908,-2.582236554,1.338899069,1.340119628,-9.6177589,-11.79234985,-10.83293998,-8.024904022000001,-10.17396596,-7.264634697000001,-7.256929557,-5.459190575,-12.533419609069824,-11.383296966552734,-11.612302780151367,-12.2322416305542,-13.363469123840332 -464,464,D48L,-0.05298013,-0.088955561,-0.097753168,-0.8662987209999999,-2.3626222390000002,-0.03812019,-0.058270706,-0.047689554,-0.005580331,-0.06989354099999999,-0.108017581,-0.12215531,-0.073351026,-0.632281026,-1.1003164159999999,-2.098040779,-2.6272036990000003,1.701875386,1.352873286,-8.380416217,-11.16163553,-10.05157662,-6.947889351000001,-8.95133239,-4.789647194,-6.487669106,-4.0526626189999995,-11.353734970092773,-10.18241024017334,-10.28935718536377,-11.49856948852539,-12.55072021484375 -465,465,D48N,-0.001229758,-0.087513551,-0.084490151,-0.043579313,-1.278640676,-0.08429493699999999,-0.009649878,0.007190363000000001,-0.013362177,-0.122330143,-0.052696959,-0.122691917,-0.046288384,-0.073270492,-0.013888133,-1.048176965,-1.5091043869999998,0.797038915,1.364972925,-4.140247929,-5.172585243,-5.396025497,-2.8448286510000003,-5.634287163,-1.6535130919999999,-2.7394183360000004,-1.394143348,-6.820185661315918,-6.255112171173096,-5.678082466125488,-5.775257587432861,-5.929240703582764 -466,466,D48Q,-0.131961078,-0.07314618,-0.105064641,-0.111862622,-1.419343169,0.008091774,-0.20238143600000003,-0.06154072,0.02426692,-0.091545481,-0.054746879000000005,-0.147833796,-0.062295486,-0.16879114,-0.054934103,-1.295522101,-1.543164236,1.3046302220000001,1.429272254,-7.520102141000001,-8.746371414,-9.428718506000001,-4.403893005,-8.95201783,-6.0695099489999995,-5.718164588,-4.463772704,-10.897006034851074,-9.987523078918457,-9.021573066711426,-9.717548370361328,-11.032898902893066 -467,467,D48P,-0.080827336,-0.11438087,-1.269183872,-2.398424719,-3.204843771,-0.004874870999999999,-0.10773466,-0.053920011,0.006210483,-0.055903086,-0.172858653,-1.1632026659999999,-1.375165077,-2.241638598,-2.555210839,-2.788320258,-3.621367283,0.711781696,0.096134008,-9.039518199,-10.47138036,-9.546170471,-6.918922417,-9.631570824,-8.629546928,-6.871316575,-3.7344460660000003,-11.185052871704102,-12.978569030761719,-11.036345481872559,-12.525291442871094,-9.2564697265625 -468,468,D48S,-0.074913959,-0.096409204,-0.054405515,-0.064171536,-0.813724545,0.024432878999999998,-0.09688527599999999,-0.052942642000000005,0.118417381,-0.04344034,-0.149378068,-0.061143509000000006,-0.047667521,-0.084699665,-0.043643405999999996,-0.613566991,-1.0138820990000001,1.416673241,1.7031394080000002,-5.163692212,-6.830438965,-4.054695892,-3.036894821,-6.587765289,-5.308666092,-4.447010527,-2.9711743160000004,-8.424028396606445,-8.570892333984375,-8.156702041625977,-7.988513946533203,-9.27997875213623 -469,469,D48R,-0.11589267,-0.0837135,-0.11721174599999999,-1.6651416469999998,-2.492796019,0.035414421,-0.134315481,-0.097469859,0.004127587,-0.057294667,-0.110132332,-0.077130002,-0.15729349,-1.546433271,-1.783850022,-2.322142265,-2.663449773,0.8295497190000001,0.7076000790000001,-6.257029062000001,-8.264170181,-7.541027778999999,-2.657672287,-6.89273999,-5.929535072,-5.331222598,-2.759665453,-12.90789794921875,-11.437992095947266,-10.701591491699219,-10.994122505187988,-12.371196746826172 -470,470,D48T,-0.064041246,-0.108630535,-0.057822122000000004,-0.367886041,-2.654013198,0.010182702,-0.069768317,-0.058314175,0.057592699000000004,-0.09015537900000001,-0.12710569,-0.161425843,0.0457816,-0.315159943,-0.42061213799999997,-2.15048201,-3.157544386,1.702262833,1.358159087,-7.424551889,-9.218329796,-7.7203313289999995,-5.349161728,-8.602973022,-6.23196357,-5.79117872,-4.231739056,-11.397650718688965,-10.049798011779785,-9.920486450195312,-9.18941593170166,-11.14279556274414 -471,471,D48W,-0.109849701,-0.040945854,-0.45716779399999996,-1.85071631,-2.496025715,0.028060288,-0.11683379599999999,-0.102865605,-0.06255472200000001,0.004283766,-0.086175474,-0.307053594,-0.607281993,-1.806129425,-1.895303195,-2.704993603,-2.287057826,1.397193541,0.7431151020000001,-9.987571747999999,-11.82792661,-10.29547212,-8.165910286,-10.90272674,-8.745822983,-7.624950393,-5.618271432,-12.00551986694336,-12.602121353149414,-14.03187370300293,-13.942766189575195,-15.361135482788086 -472,472,D48V,-0.123436205,-0.100342418,-0.076115092,-0.802442827,-2.229344399,-0.029461296,-0.119148332,-0.12772407800000002,0.117227071,-0.071392855,-0.12929198,-0.112590645,-0.039639537999999995,-0.508733714,-1.09615194,-2.227872348,-2.23081645,1.70056127,1.340006709,-7.671322885,-9.954720764,-9.650167519,-6.000151542999999,-8.642467163,-4.109107437,-6.420206583,-4.057035537,-10.82758903503418,-9.732461929321289,-10.023240089416504,-10.684062957763672,-11.093527793884277 -473,473,D48Y,-0.12049191599999999,-0.112136982,-0.10733534900000001,-1.531847575,-2.515503785,0.09027948400000001,-0.124141695,-0.116842137,0.030967337,-0.095083228,-0.129190735,-0.12601986,-0.088650837,-1.659857797,-1.4038373530000001,-2.604479465,-2.426528104,1.026334181,0.714551904,-8.815443292000001,-11.13765137,-10.90940261,-6.745146523,-8.927507111,-6.3575088420000005,-6.6110460689999995,-4.396986032,-11.210309028625488,-10.53697681427002,-11.40310287475586,-11.026350975036621,-12.11330509185791 -474,474,L49A,0.009349389,0.027332928,0.025682542000000003,0.055011924000000004,-0.398791157,0.13333304699999998,0.079372151,-0.060673372999999996,0.01561417,0.04270075,0.011965105,0.025337053,0.026028031,0.010342192,0.099681656,-0.314749226,-0.48283308799999997,1.070193421,1.722549574,-5.457597258,-3.935032722,-6.5913870160000005,-6.7633763810000005,-5.145233757,-4.852956413,-4.425792864,-2.822849572,-4.604328155517578,-8.566088676452637,-2.6922245025634766,-2.5272703170776367,-6.331650733947754 -475,475,L49C,-0.021389187,0.017867822,-0.050937995,-0.07269455799999999,-1.730716884,0.143915038,0.086171289,-0.128949662,0.01049764,0.026932611000000002,0.008803033,-0.00948844,-0.09238755,-0.080019973,-0.065369143,-1.6481639940000001,-1.8132697740000001,0.8294104390000001,1.321010994,-7.1968489270000005,-6.918421295,-7.414606322999999,-8.045412674,-6.099771652,-7.506032692000001,-5.765158037999999,-4.073882429,-6.493422508239746,-10.037704467773438,-7.398804187774658,-6.668956279754639,-9.799886703491211 -476,476,L49E,-0.050972354000000004,-0.01507065,-0.11613341,-1.629462955,-2.506298315,0.134466741,0.018211701,-0.120156409,-0.101759721,-0.04706364,0.016922341,-0.11310782900000001,-0.11915899099999999,-1.422198118,-1.836727791,-2.266929679,-2.74566695,1.0240189309999999,0.744975886,-8.526647083,-8.00509449,-8.315389046,-9.800883865,-7.740665572999999,-8.771202438,-6.99453887,-5.329296923999999,-6.279171466827393,-11.350597381591797,-4.440325736999512,-6.028165817260742,-7.154123306274414 -477,477,L49D,0.041772056,-0.006964522,-0.8013396559999999,-1.836841629,-2.389768248,0.08594894199999999,0.121567522,-0.03802341,-0.011381275,-0.017441174,0.00351213,-0.63787737,-0.964801942,-1.298282455,-2.3754008030000002,-1.921165266,-2.85837123,3.992482255,2.95605532,-9.545601109,-8.309635139,-9.783354468999999,-10.31336359,-7.804341591,-11.51731075,-6.7227783389999995,-5.02631127,-7.400524616241455,-12.594196319580078,-5.349582672119141,-6.588474750518799,-8.276944160461426 -478,478,L49G,-0.064166624,0.008118386,-0.002153457,-0.320083165,-1.948571412,0.12403715800000001,-0.005082992,-0.123250256,-0.016565513,0.029607226,-0.013370453999999999,0.043468152999999995,-0.047775067000000004,-0.154749104,-0.485417225,-1.596316712,-2.3008261119999998,1.142290726,1.356521415,-7.374615791,-5.908962562999999,-8.398892944,-8.771806847,-6.253803734,-7.539612869,-5.466906267000001,-4.2122122289999995,-6.659244537353516,-10.123635292053223,-4.998256683349609,-4.343631267547607,-8.569408416748047 -479,479,L49F,0.02032381,0.032874772000000003,-0.033435021,-0.009401590999999999,-0.12134167,0.039480809,0.101180947,-0.060533327000000005,-0.012496168,0.047206276,0.018543267,-0.00948844,-0.057381601,0.0068000840000000005,-0.025603265,-0.130049039,-0.1126343,1.30067394,2.192009275,-4.206474565,-3.8890072019999997,-3.5334593510000003,-5.698352531,-3.880069344,-4.031484398,-5.320025335,-2.76166752,-7.156952857971191,-7.269779205322266,-6.413846015930176,-6.739011764526367,-6.6212921142578125 -480,480,L49I,0.036011655,0.070637907,0.029063234,0.087087169,0.025955322000000003,0.057718676,0.09683095,-0.024807641000000002,0.053431942,0.09419010800000001,0.047085705,0.086334478,-0.02820801,0.128152554,0.046021783,0.034742236,0.017168408,1.123099029,2.88447331,-4.201768993,-4.49939605,-3.979560875,-5.099177238,-3.776219185,-3.654491615,-4.987080959,-1.633741849,-3.9978690147399902,-6.121174335479736,-3.3622703552246094,-4.488376617431641,-4.581637382507324 -481,481,L49H,0.037321676,0.040130584,0.016879658999999998,-0.30972323399999996,-1.904127979,0.080282989,0.110478231,-0.035834879,-0.083165663,0.043975350999999996,0.036285817000000005,0.004107976,0.029651342,-0.235894832,-0.38355163600000003,-1.51731899,-2.290936968,1.391661667,1.418493416,-8.119471825,-7.036610275,-7.789581207,-9.343039856,-6.60913475,-9.818993034,-6.379508257,-4.8968305910000005,-8.13456916809082,-11.401464462280273,-5.710080146789551,-7.547232627868652,-9.563196182250977 -482,482,L49K,-0.023105191,-0.015099101,-0.055811554000000006,-1.172874741,-1.8574220769999998,0.092617117,0.043165542,-0.08937592300000001,-0.035995509,-0.027003846,-0.003194355,0.0075449,-0.11916800699999999,-0.7156510159999999,-1.630098465,-2.078896516,-1.635947637,1.701504418,1.3525151930000001,-6.80907211,-6.085711197,-7.006059845,-8.131258675,-6.679611641,-6.142719193,-5.487785693999999,-4.780601221,-8.297194480895996,-12.38228988647461,-4.852334976196289,-7.897103309631348,-10.132519721984863 -483,483,L49M,-0.025127699,0.009347731,-0.032989389,-0.0039046209999999996,0.008772386,0.065390268,0.004610341,-0.054865738,-0.036097686000000004,0.052901212,-0.03420575,0.031129411000000003,-0.097108189,0.045372268,-0.053181509,0.010800848,0.006743923000000001,1.144223292,2.691488135,-3.906448198,-3.4795968630000003,-4.386310905,-3.644842995,-4.088151375,-3.933338852,-5.054741694,-3.040362369,-5.04459810256958,-6.186845779418945,-4.71026611328125,-4.416617393493652,-4.806087970733643 -484,484,L49N,-0.007183726999999999,0.017364313,-0.054132898,-0.37150374399999997,-1.9282989640000001,0.10714061300000001,0.053262029,-0.067629483,-0.103100289,0.010271114,0.024457512,-0.079657665,-0.02860813,-0.20027932699999998,-0.54272816,-1.770774069,-2.085823858,1.2418821000000002,1.349998314,-8.368614497000001,-7.795747177000001,-7.38650573,-9.930825783,-7.014296379,-9.715697418,-6.592324491,-4.151768701,-6.76390266418457,-11.256648063659668,-4.530117511749268,-6.106276512145996,-8.857967376708984 -485,485,L49Q,-0.122437675,-0.024370565,-0.067796907,-0.09092469800000001,-1.7597983990000001,0.172771444,-0.065991565,-0.178883785,-0.045454654000000004,0.026513727999999997,-0.07525485700000001,-0.035295703,-0.10029811,0.025722837000000002,-0.207572233,-1.929598434,-1.589998363,0.590648405,1.296740411,-6.637604391,-5.722825622999999,-6.389389397,-7.7175752939999995,-5.719410827999999,-7.638820816,-5.175834603999999,-4.4689533610000005,-6.4939141273498535,-10.865777969360352,-4.786863803863525,-5.63131856918335,-7.759264945983887 -486,486,L49P,-0.028853608,0.024618252,-0.004727614000000001,-0.244371135,-1.963572886,0.108744719,0.057783565,-0.11549078,-0.089990344,0.023801475,0.025435028999999998,0.011027928999999999,-0.020483156000000002,-0.121030383,-0.367711886,-1.80662293,-2.1205228419999997,0.9783723940000001,1.320525046,-4.882713327,-4.383366791,-5.3001195139999995,-5.742442116,-4.44438121,-4.543257004,-4.016912262,-2.350246851,-5.564274787902832,-9.547039031982422,-4.4170241355896,-5.134319305419922,-7.452921390533447 -487,487,L49S,-0.027019788,-0.012416005,-0.022086376,0.002435373,-1.6766709219999998,0.11216828,0.057931305,-0.111970881,-0.00752886,0.010928307,-0.035760317,0.008531186,-0.052703937,0.018574518,-0.013703772,-1.344999869,-2.008341975,0.78865909,1.338309624,-5.546601926,-4.828681823999999,-5.266731285,-6.797354912,-4.885446953,-5.954794655,-4.195069406,-2.669018597,-5.425747394561768,-8.606517791748047,-3.47605037689209,-4.832266807556152,-7.192955493927002 -488,488,L49R,-0.0076694680000000005,0.006198338,-0.036104698,-1.39980136,-2.058053405,0.092936331,0.038281703,-0.053620638,-0.080341118,-0.011225215,0.02362189,0.0017070339999999999,-0.073916429,-1.083368443,-1.7162342769999999,-1.490933372,-2.625173437,3.555143042,2.8807042089999997,-7.1962183589999995,-4.844845825,-7.79799662,-8.165689331,-6.389884467999999,-8.782675552,-5.561558235,-4.512566393,-7.6953558921813965,-11.156163215637207,-4.353302478790283,-6.719803333282471,-9.278738021850586 -489,489,L49T,0.027307709,0.020935829,-0.007092364,0.003132137,-0.566029879,0.075163415,0.088277447,-0.033662028999999996,-0.020952672,-0.030656021000000002,0.072527679,0.000611887,-0.014796615,0.0070444819999999995,-0.000780208,-0.46115632100000004,-0.670903437,0.756821849,1.468778458,-4.128080345,-3.117119972,-4.889680756000001,-4.994410072,-3.749801727,-3.889389198,-3.119054137,-0.258416625,-2.826291799545288,-6.178128242492676,-1.8960939645767212,-2.662888765335083,-4.5996832847595215 -490,490,L49W,0.051489205,-0.007868046,0.018648243999999998,0.01802376,-0.076008527,0.054655533,0.09516925400000001,0.007809155999999999,0.005888109,0.021086182000000002,-0.036822272999999996,0.030752778999999997,0.006543709,0.024839426,0.011208093,-0.016414935,-0.135602119,1.4848678430000002,2.833193077,-9.161803276,-8.75562529,-8.953390945,-9.456890747000001,-8.146909698,-10.496199699999998,-8.343969717,-7.057598991,-9.42554759979248,-10.949627876281738,-8.04041862487793,-9.085886001586914,-9.485491752624512 -491,491,L49V,0.019838762,0.038435602,0.034548711,-0.006204268000000001,-0.043917615,0.073670734,0.098679154,-0.05900163,-0.034816585,0.054191768,0.022679436,0.111489675,-0.042392253,0.06792521900000001,-0.080333755,-0.005456366999999999,-0.082378863,1.227003906,2.729191112,-3.729945303,-3.74064769,-3.9293603439999996,-4.5862417980000005,-3.98576049,-2.4077161940000003,-3.506266077,-1.7379779180000001,-2.9213061332702637,-6.85789680480957,-2.9752564430236816,-2.8259289264678955,-4.660107612609863 -492,492,L49Y,0.004036225,0.016423706,0.0053643480000000006,-0.004842150999999999,-0.105296504,0.104310184,0.05043952,-0.042367071,0.005522336,0.023349396,0.009498015,0.016593362,-0.005864666,0.025067903,-0.034752204,-0.08315244299999999,-0.127440564,1.307360183,2.3420552519999998,-6.931931645,-6.5976871489999995,-6.528364868,-8.117919441,-5.417604927,-7.998081841,-6.2466944820000005,-3.9382902160000004,-8.738117218017578,-9.415600776672363,-6.587198257446289,-7.630993843078613,-8.684340476989746 -493,493,N50A,-0.008084997,-0.010696856000000001,-0.036183766,-0.002009195,-0.032218326,-0.001880045,-0.012713661000000001,-0.0034563320000000003,0.045044948,-0.026481223999999998,0.005087513,-0.009799657,-0.06256787400000001,-0.003001677,-0.001016713,-0.030726706,-0.033709946,1.297699302,2.592330939,2.2259235719999997,1.8297348180000002,2.450700096,3.0323687130000003,2.3535903240000002,1.463223907,0.400537436,1.050228126,-2.694357395172119,-3.241149425506592,-2.1966841220855713,-2.4801578521728516,-3.6655311584472656 -494,494,N50C,-0.019290946,-0.029554896,-0.013085316999999999,0.027809537000000002,-1.223080702,0.094070154,0.015158235,-0.053740127,0.004290877,-0.017488304,-0.041621488,0.020282463,-0.046453097,-0.003367603,0.058986677,-0.851844498,-1.594316905,0.406638,1.336012309,-3.64956243,-3.7607690810000003,-3.199836121,-2.476058411,-3.9504446110000004,-4.860703926,-5.2432662919999995,-4.2966612060000005,-8.169867515563965,-8.571914672851562,-9.273981094360352,-8.111772537231445,-10.448354721069336 -495,495,N50E,-0.010813871000000001,-0.023545543,-0.060759267,-0.006930653,-0.017852372,-0.032640196,-0.033614369,0.011986628000000001,0.066806717,-0.029349772000000003,-0.017741313999999998,-0.039526473,-0.08199206,-0.034967358,0.021106053,-0.020463977,-0.015240766000000001,1.274597881,2.5472242119999997,-0.01725918,0.191334946,0.371022591,0.774214348,-0.838738647,-0.584129135,-1.6390932280000001,0.7687530359999999,-2.297908067703247,-4.098039627075195,-3.1348376274108887,-3.0725951194763184,-4.343049049377441 -496,496,N50D,-0.000362991,-0.001021611,-0.000616795,0.031498602,-0.01891356,-0.056921607,-0.028705487999999998,0.027979506,-0.01299482,0.014256395,-0.016299617,0.013993381000000001,-0.01522697,-0.006421268000000001,0.069418471,-0.012425397,-0.025401722999999998,1.296986275,2.686218378,-0.21624642600000002,-0.489789825,-0.296828812,-0.176204269,-0.037966698,-0.080442528,-2.757522432,1.189025998,-2.1335458755493164,-3.563338279724121,-3.7050395011901855,-2.6809539794921875,-3.3792290687561035 -497,497,N50G,0.010918123,-0.011505466,-0.012991626000000001,0.013356463999999998,-0.018879235,-0.019337947,0.002186642,0.019649603,0.027401514,-0.026275782,0.00326485,-0.013422628,-0.012560624,-0.018677283,0.04539021099999999,-0.042923502999999995,0.005165033,1.4636455019999999,2.58767748,0.254996309,0.581983315,0.148864204,0.684148949,0.8590724259999999,-0.9990873490000001,-0.856568856,1.4604560130000002,-3.997565984725952,-2.96535062789917,-3.5795886516571045,-3.698066234588623,-3.695441246032715 -498,498,N50F,-0.000322013,-0.039831523,-0.0046451470000000005,-0.014366638999999999,-0.082938465,0.0028897959999999996,-0.004918116,0.00427409,0.047196745,-0.041833332,-0.037829714,-0.006184821,-0.003105473,-0.017278688,-0.01145459,-0.091616967,-0.074259963,1.230673727,2.2066767780000003,-3.587364079,-3.609142075,-3.1745982280000002,-2.542659355,-4.07961438,-4.530806358,-5.335282447,-3.625255995,-7.067098140716553,-7.637969970703125,-7.003608703613281,-7.719845771789551,-8.467220306396484 -499,499,N50I,-0.007572026999999999,-0.053279155,0.00296178,0.040509752999999996,-0.050837260999999995,-0.015527808999999998,-0.036051868,0.020907815,-0.015567777,-0.071961083,-0.034597226,-0.0038257729999999998,0.009749333,-0.01649428,0.09751378599999999,-0.05649143400000001,-0.045183087999999996,1.315948249,2.403880648,-1.970203613,-1.706909698,-1.450253075,-0.9756854779999999,-2.3660438999999998,-3.3521259160000003,-4.658404872,-2.2496345509999998,-5.975914001464844,-6.447565078735352,-5.219825267791748,-6.5388288497924805,-7.408339977264404 -500,500,N50H,0.02568454,-0.007074709,-0.002432786,0.057300434000000004,0.010744473999999999,-0.027480612,0.004180202,0.047188878,-0.060775539,-0.020669504,0.006520087,0.000924055,-0.0057896269999999994,0.031719916,0.082880951,0.001127745,0.020361203,1.170341736,2.572464589,-0.970511105,-0.013208983999999998,-1.108956573,-0.457947472,-1.7241500930000002,-1.5482924040000001,-2.619911038,-1.105208958,-5.0167622566223145,-5.201453685760498,-4.863048553466797,-4.987606048583984,-6.039527416229248 -501,501,N50K,0.038498322,0.030005389,0.036899416000000004,0.020504778,-0.000322556,-0.011371362,0.043571270999999995,0.033425372,-0.035305857999999996,0.0023998229999999997,0.057610955,0.056866925,0.016931906,-0.00741841,0.048427965999999996,0.00143379,-0.002078901,1.177895262,2.6053618,0.165758078,0.71181105,0.634507935,0.6136717070000001,-0.838377167,-0.292823135,-2.7293754889999997,0.153071996,-4.238479137420654,-5.306432247161865,-3.098783016204834,-4.147744178771973,-5.618863582611084 -502,502,N50M,0.025102831000000003,0.08440997,0.070633363,0.061432125,0.051670550999999995,-0.033725571,0.026342955,0.023862707,-0.014325853999999999,0.087391532,0.08142840700000001,0.073637135,0.06762959,0.077752052,0.045112198,0.048596027,0.054745074000000005,1.1122792190000002,2.6324447930000003,-2.7263591419999997,-2.9214538039999995,-1.9133663330000001,-1.986578133,-3.002580048,-3.80781739,-4.956621297,-3.4971831489999996,-6.678380966186523,-7.368645191192627,-6.375278472900391,-7.204399108886719,-7.8475847244262695 -503,503,N50L,0.004176773,-0.003928236,0.0027932440000000003,0.035434022999999995,-0.025187337999999997,0.011849506999999999,-0.000929413,0.009282959,0.018310207,-0.005951341999999999,-0.001905129,-0.000528841,0.006115328000000001,-0.013932711,0.08480075599999999,-0.026614968,-0.023759707,1.4150288999999998,2.619920111,-1.746993504,-1.7708842009999999,-1.0075930020000001,-0.7902606120000001,-1.885758064,-3.2804716419999997,-3.560377453,-2.7220580869999997,-5.504016876220703,-6.360739707946777,-5.250582695007324,-5.763498783111572,-7.06842041015625 -504,504,N50Q,-0.034149908,-0.025746897,-0.0055602740000000005,-0.0048038379999999995,-0.030864238999999998,-0.026081816,-0.070732568,0.0024327520000000003,-0.080925792,-0.040319285,-0.011174509,0.001889087,-0.013009635,-0.047476969,0.037869293,-0.002095514,-0.059632964000000004,1.2387622759999999,2.562574386,0.18016377600000003,0.761212715,0.252830681,0.6724545670000001,-0.659473778,-0.126205307,-2.391201077,-0.19100037399999997,-3.913844347000122,-4.630012035369873,-3.4819343090057373,-3.4831674098968506,-4.853610038757324 -505,505,N50P,-0.023845295,-0.023818331,-0.04224872,-0.004277632,-0.037237915,0.019940608999999998,-0.027595201,-0.020095388999999998,-0.05125764,-0.028868498,-0.018768164,-0.033057906,-0.051439534,-0.039822982,0.031267718,-0.031779322,-0.042696507,1.34675048,2.55281712,-1.500244243,-1.6503931580000002,-1.89874144,-1.011499504,-0.812555473,-2.128031639,-4.168961106,-1.4798279490000001,-4.636159420013428,-6.139608860015869,-4.895085334777832,-3.898867130279541,-5.41187047958374 -506,506,N50S,0.005311758000000001,0.008731341,0.002270534,0.035178948,-0.013873543,-0.0035212240000000003,0.005232586,0.00539093,0.018288786,-0.006976869,0.02443955,0.030300538,-0.025759471000000003,0.022035366,0.048322529,-0.004379002,-0.023368084,1.211511191,2.5712777780000002,0.558419965,0.226065842,0.882407875,1.171736046,0.49760156299999997,0.014288498,-1.8701244259999998,-0.053767358,-3.1920828819274902,-3.6903247833251953,-3.1060285568237305,-3.4817862510681152,-3.85798978805542 -507,507,N50R,-0.023695211,-0.023526738999999998,-0.020184106,0.018598537,-0.036412892999999995,-0.017556824,-0.031681548999999996,-0.015708873,-0.02769758,-0.021082536000000002,-0.025970941,0.005270632,-0.045638844000000005,0.0061453390000000005,0.031051733999999998,-0.011810751000000001,-0.061015035,1.3081624109999999,2.665652859,-0.215722052,0.604579834,0.275983498,0.7266398159999999,-1.117773582,-1.568039825,-2.464228779,-0.042224125,-5.4033379554748535,-5.968600749969482,-4.519298076629639,-4.969758987426758,-6.488803863525391 -508,508,N50T,-0.014458038999999999,0.015155161,0.0032819570000000003,0.006063689000000001,-0.008385861,-0.004020308,-0.034910673999999996,0.005994597,-0.012008907,0.006723221,0.023587101,0.017023227,-0.010459313000000001,-0.010463799000000001,0.022591176,-0.005723173000000001,-0.011048549,1.215730156,2.850969187,0.7814481809999999,0.423739418,1.498049065,1.4379926219999999,0.85495237,-0.307492569,-1.138271929,-0.19074585300000002,-3.49320650100708,-4.028925895690918,-3.3461368083953857,-3.543957471847534,-4.444907188415527 -509,509,N50W,-0.0015829079999999998,0.008164795,0.013075457,0.011461233999999999,-0.021802642999999997,0.014398281,-0.008749722,0.005583906,-0.042639055999999995,-0.006706111,0.0230357,-0.008355088,0.034506001,0.015032656,0.007889812,-0.046507617,0.0029023309999999997,1.1321617,2.338242551,-4.470520325,-3.93557135,-4.3416647489999995,-3.633132561,-4.841911774,-5.60032119,-5.976090782999999,-4.091725199,-8.97309684753418,-10.050683975219727,-9.15682601928711,-9.708450317382812,-10.389427185058594 -510,510,N50V,0.004001322,-0.020066022,-0.030175905,0.0158949,-0.016311532,-0.024784184,-0.013346486999999999,0.02134913,-0.001813341,-0.041030499,0.0008984560000000001,-0.030887137000000002,-0.029464672999999997,-0.015422700000000001,0.0472125,-0.035472317999999996,0.0028492540000000003,1.194165551,2.437284771,-0.18853255300000002,0.055017342000000004,0.674477478,0.9079105909999999,-1.039512703,-1.5405554730000002,-2.4907028280000003,-1.178196581,-4.615966796875,-5.294435501098633,-4.246381759643555,-4.946063041687012,-5.9392595291137695 -511,511,N50Y,0.008904689,-0.01490496,-0.007164311,0.0052608690000000005,-0.041849916,-0.009206242,-0.00633791,0.024147288,-0.04517863900000001,-0.028905446,-0.000904474,-0.060033695,0.045705073,-0.024686081000000002,0.035207819,-0.062449657,-0.021250174,1.258514628,2.348652214,-3.372337065,-2.6386307909999998,-3.194357246,-2.819585014,-3.834533493,-4.374578781,-5.096726983,-3.1133120080000003,-7.076103687286377,-7.432498455047607,-7.161799907684326,-7.741429328918457,-7.904517650604248 -512,512,S51A,-0.003110825,0.0039510990000000005,-0.002442861,0.00882037,-0.739318788,0.024115962999999997,0.002104804,-0.008326454,-0.013147998999999999,0.0036820940000000003,0.0042201040000000006,-0.021728466000000002,0.016842745,-0.013778041999999999,0.031418781,-0.505529847,-0.9731077290000001,1.151533062,1.621697353,-3.0278721369999997,-2.941236496,-2.868091484,-3.423185524,-2.181104836,-3.7257423480000003,-5.461872252,-2.343243786,-6.895944595336914,-8.082379341125488,-6.524526596069336,-7.04013729095459,-7.905231475830078 -513,513,S51C,-0.044688877,0.04816891,-0.032840674,-0.7806645590000001,-1.8187439930000002,0.104584094,-0.015782624,-0.07359513,-0.102106469,0.096158638,0.000179181,-0.058497062,-0.007184286,-0.468763857,-1.0925652609999998,-1.6840355359999999,-1.95345245,1.7562629330000001,1.4843052959999998,-7.2528247420000005,-7.147603569,-7.074056937999999,-7.5452739179999995,-7.076808739,-7.420380547000001,-8.046940046,-4.016271463,-9.863029479980469,-10.684961318969727,-11.028426170349121,-9.654426574707031,-11.280588150024414 -514,514,S51E,-0.024542575,0.008071454,0.012977032,-0.004208255,-0.086824363,0.03604074,-0.045042871,-0.004042279,0.008550784,-0.025929063999999998,0.042071972,0.010381706,0.015572358,0.020291975,-0.028708485,-0.07252976900000001,-0.101118956,1.311983428,2.384162345,-3.871490565,-3.833378555,-3.3650324780000003,-4.282151802,-2.713734848,-5.163155144,-5.9192918510000005,-2.2283248419999997,-5.913559913635254,-8.733728408813477,-7.34791374206543,-7.7933478355407715,-7.58349609375 -515,515,S51D,0.010510866,0.05345856400000001,0.052309327,0.086368427,0.075247281,0.044138814000000005,0.0031317940000000002,0.017889938,-0.096845128,0.020697981,0.086219147,0.044549621,0.060069032,0.10654020300000001,0.066196651,0.074847804,0.075646758,1.12715838,2.9269820889999996,-2.454435864,-2.94208355,-2.0708425669999997,-2.443288925,-1.519681465,-3.2962828139999996,-4.078479491,-0.965591405,-3.928957462310791,-5.583185195922852,-6.592037200927734,-6.104689598083496,-5.493010520935059 -516,516,S51G,-0.011771686000000002,-0.025383054,-0.042533506,-0.004001896,-0.36904324899999996,0.019691329,0.017543543,-0.041086914,-0.09799392400000001,-0.06165488400000001,0.010888776999999999,-0.067776709,-0.017290303,-0.061332715,0.053328923,-0.297714451,-0.440372046,1.287357844,1.840626853,-2.611165483,-2.611798157,-2.0271894,-3.066989006,-1.471996712,-3.8778541410000003,-4.407296703,-0.915042685,-5.9922895431518555,-7.425993919372559,-7.440368175506592,-6.687804222106934,-7.189764022827148 -517,517,S51F,-0.035170724,0.10573728199999999,0.033076164,-0.042512380999999995,-1.75070567,0.080784026,0.017316009,-0.087657457,-0.109479009,0.117052398,0.094422165,0.094471129,-0.028318801,-0.114003916,0.028979155,-1.7320144869999998,-1.7693968519999999,0.839714032,1.315902222,-7.835615195,-7.277496925,-8.014218796,-7.443705856,-8.838178597,-7.6044758,-7.534595329,-3.9354022160000004,-10.849048614501953,-12.542339324951172,-11.331537246704102,-10.819973945617676,-12.139533996582031 -518,518,S51I,-0.037858996,0.010978864,-0.08603620099999999,-0.12256795,-1.3358577059999999,0.03767522,0.0008225060000000001,-0.076540498,-0.083073513,0.006331635,0.015626092,-0.055225953,-0.116846449,-0.021163636,-0.223972263,-1.3119146879999999,-1.3598007230000002,0.806239679,1.3435049330000002,-8.267238387999999,-7.683211151,-9.09937365,-8.837461647000001,-8.609893585,-7.106251907000001,-8.590728581,-5.655949529,-10.469649314880371,-10.884723663330078,-10.679346084594727,-10.345130920410156,-11.506784439086914 -519,519,S51H,-0.054228684000000006,0.0054848430000000005,-0.064991767,-0.032996085,-0.605656207,-0.033705065,-0.049184278,-0.059273089,-0.09714614099999999,0.038050709,-0.027081023,-0.030288051,-0.099695483,-0.058124565999999996,-0.007867604,-0.42029362600000003,-0.7910187870000001,1.428583659,1.8655639659999999,-6.307050037000001,-6.362521996,-6.069293854,-5.781919014,-5.9927863310000005,-7.328728989,-7.237775376,-4.132124773,-7.806182384490967,-9.580047607421875,-7.862458229064941,-8.334465026855469,-9.167049407958984 -520,520,S51K,-0.006533424,0.005048771,-0.093152136,-0.080652788,-0.6689583339999999,0.07220687,0.048637355,-0.061704203,-0.119065481,-0.016599262,0.026696803999999998,-0.13731219,-0.04899208099999999,-0.09405368900000001,-0.067251886,-0.44670727600000004,-0.891209391,1.449739916,1.841853729,-4.354200017,-4.316860825,-4.09650045,-4.531218788,-3.8721615369999998,-4.9542584839999995,-6.352390757,-2.704196405,-7.604623794555664,-9.188676834106445,-7.641393661499023,-7.943068504333496,-8.34605884552002 -521,521,S51M,-0.00846214,0.03231386,0.02757966,-0.011123828999999998,-1.386030888,-0.007682441,-0.025330468,0.008406188,-0.081490858,0.011582936,0.053044783,0.0015388720000000002,0.053620447,0.002445255,-0.024692912,-1.148562968,-1.6234988080000001,0.705857139,1.344347789,-7.432698781,-6.830210938,-7.346100975,-8.393603012,-7.840288414,-6.753290565,-7.830402536,-5.191827577,-11.226258277893066,-11.739079475402832,-11.157520294189453,-10.197943687438965,-11.726449966430664 -522,522,S51L,-0.0022791929999999997,0.021024867000000003,-0.003305348,-0.008331066,-1.4616226030000001,0.067083038,0.030187877999999998,-0.034746264,-0.11909463,0.000102935,0.041946798,-0.027660432000000002,0.021049737000000002,-0.036061742,0.01939961,-1.373298063,-1.549947142,0.818098972,1.338460985,-7.41173073,-6.863543877000001,-7.307715195,-8.22782988,-8.244294449,-6.415270248,-7.437962989,-4.726175625,-9.48106575012207,-10.205596923828125,-9.138487815856934,-9.81421947479248,-10.725178718566895 -523,523,S51N,0.012952954,0.044632218,0.025758462000000003,0.037980149,0.017691821,-0.009411787,0.000466381,0.025439527000000003,-0.081189369,0.009704242,0.079560193,-0.018141268000000002,0.06965819200000001,0.00282491,0.073135387,0.0040961240000000005,0.031287517,1.1435320759999998,2.702124819,-2.258556158,-2.811522507,-2.279665062,-2.3816689380000002,-1.338768349,-2.481155937,-3.898803444,-1.192555578,-4.860686302185059,-5.28381872177124,-5.330394744873047,-5.288689136505127,-5.181239128112793 -524,524,S51Q,-0.014713446000000002,-0.034990407,-0.019036116000000002,-0.023834078999999998,-0.454083284,0.009577845,0.006072406999999999,-0.035499298,-0.09589581900000001,-0.065663737,-0.004317077,-0.012125125,-0.025947107,-0.018350611,-0.029317546,-0.271114101,-0.6370524670000001,1.385069754,2.021961315,-5.034011494,-5.058857224,-4.77027462,-4.957090347,-4.216345703,-6.167489578,-6.145465445,-3.237922399,-6.906723499298096,-8.835315704345703,-7.136561393737793,-7.83720064163208,-8.477293014526367 -525,525,S51P,-0.062556613,-0.007302388000000001,-0.276801636,-1.687142933,-2.620159281,0.086343981,-0.03463264,-0.090480586,-0.102501425,-0.006680586999999999,-0.007924189,-0.226428925,-0.327174346,-1.6181337169999999,-1.7561521480000002,-2.56153363,-2.6787849319999997,1.292604661,0.756880075,-6.937806532000001,-5.962718079,-6.621341567999999,-6.86277375,-7.021867477000001,-8.220331787000001,-7.251630502,-3.5850306830000003,-10.289835929870605,-11.826749801635742,-10.237058639526367,-10.189367294311523,-10.503540992736816 -526,526,S51R,-0.02499057,0.0028453190000000002,-0.014492931,-0.01861232,-1.166772263,0.055392326,0.016255882,-0.066237022,-0.048319258,0.027761782000000002,-0.022071145,-0.020645703,-0.008340158,-0.040765707000000005,0.003541067,-0.83249896,-1.501045565,0.9259420279999999,1.4212439319999999,-3.9978607860000004,-3.7832409210000004,-4.080841171,-3.5212994610000004,-3.37298732,-5.230935059,-5.785746712000001,-2.413292354,-8.303086280822754,-9.47379207611084,-7.779054641723633,-7.727207183837891,-9.0244779586792 -527,527,S51T,-0.029466071,-0.02768787,-0.010498036,0.002427636,0.006249996999999999,0.0068755069999999995,-0.02033942,-0.038592721,-0.020247936,-0.021796997000000002,-0.033578743,-0.002413765,-0.018582306,-0.013253448999999999,0.01810872,0.005396449,0.007103544,1.312553584,2.661026548,-0.9036472090000001,-0.8193224640000001,-0.824447632,-1.401025665,-1.502978355,0.029538071000000003,-3.137374733,0.47825707700000003,-3.4574427604675293,-3.9963300228118896,-4.246950626373291,-3.315382957458496,-3.583064079284668 -528,528,S51W,0.001588234,0.003864143,-0.000930465,-1.257708532,-2.260674765,0.099042763,0.025701697000000003,-0.022525229,-0.097666566,-0.026890097999999998,0.034618382999999996,-0.019694977,0.017834048,-1.069810325,-1.445606739,-1.749968803,-2.7713807260000003,2.825242121,2.091728656,-8.809051311000001,-8.198051941000001,-8.730688751,-9.177346962,-8.570997597,-9.368171302999999,-8.73605875,-6.163029839,-12.143014907836914,-14.45495891571045,-12.64030933380127,-12.771747589111328,-13.7830228805542 -529,529,S51V,0.044296827999999996,0.035245693,0.023986122000000002,0.024310053999999998,-1.719458446,0.070797273,0.093772269,-0.005178614000000001,-0.11410686699999999,0.014602406,0.05588898,-0.018460083999999998,0.066432328,-0.010619651,0.059239759,-1.451761355,-1.987155536,0.713452036,1.3220253290000001,-7.48566114,-7.014602699,-7.7567631,-8.047302361,-7.371370811,-7.238266731,-7.909634371,-4.879930185,-10.156492233276367,-11.097905158996582,-10.334174156188965,-10.280707359313965,-11.529086112976074 -530,530,S51Y,-0.0021061,-0.001298404,0.006027365,0.014509847,-1.4192678380000001,0.021413274,0.005692476,-0.009904675,-0.169446028,-0.005156428,0.00255962,0.009832789,0.002221941,0.012159049,0.016860643999999998,-1.322282954,-1.5162527209999999,0.811011548,1.340853164,-8.981587416,-8.56538324,-9.443399207999999,-8.187927803,-9.384058197,-9.327168633,-8.31440531,-5.624510435,-10.465414047241211,-11.828227996826172,-10.825031280517578,-10.613299369812012,-11.812522888183594 -531,531,G52A,-0.047540555,-0.026315206,-0.001094208,0.004574982,-1.397547239,-0.020527633,-0.0776331,-0.017448009,0.042918952999999996,0.024074044,-0.076704455,0.036529686,-0.038718102000000004,0.03971082,-0.030560856,-0.941951731,-1.853142747,0.7054294320000001,1.362729995,-4.268182642,-4.54104258,-2.812916542,-3.755971764,-4.200309708,-6.030672615,-3.850479131,-3.44375813,-8.6969575881958,-8.301237106323242,-8.26502513885498,-7.482048034667969,-6.993022918701172 -532,532,G52C,-0.050390135999999995,0.011548613000000001,-0.506589603,-1.3907311180000002,-2.765819379,0.100262251,-0.05765877,-0.043121501,-0.039428825,0.055839367,-0.032742142,-0.274332415,-0.738846791,-1.3442512919999998,-1.437210944,-2.422823856,-3.1088149019999998,1.551748794,0.893002159,-8.177728903,-7.754408089,-7.589241081,-7.454473335,-8.278901199,-9.811620811000001,-7.6510984120000005,-7.248742476,-11.564508438110352,-12.19506549835205,-11.365510940551758,-10.414567947387695,-11.680410385131836 -533,533,G52E,-0.052895474000000005,-0.011349755,-0.02519872,-0.017728775,-1.4854190390000002,-0.032505387999999996,-0.05358206,-0.052208887999999995,-0.09541881599999999,0.038979189,-0.061678698,0.025661311000000003,-0.07605875,-0.02301791,-0.012439638999999999,-1.274221201,-1.6966168769999999,0.637829016,1.329612933,-3.8579845489999998,-4.01368042,-2.714966103,-4.00724408,-4.125222305,-4.428809837,-4.399830894,-3.096078355,-6.853265762329102,-8.459785461425781,-7.142114639282227,-7.959352016448975,-6.5692925453186035 -534,534,G52D,-0.025476422000000002,-0.028010881,0.037914649,-0.02815374,-1.142466432,0.002442821,-0.04527852,-0.0056743240000000006,0.042917138,-0.013377638,-0.042644123,0.049065029,0.026764269,-0.010629476,-0.045678002999999995,-0.962918321,-1.3220145429999999,0.523897175,1.339254332,-3.233483171,-3.293809402,-1.927869896,-2.8143798139999996,-3.9269789580000003,-4.204377785,-2.827768827,-2.447173425,-6.181418418884277,-6.429874420166016,-6.280648708343506,-6.936537742614746,-5.55529260635376 -535,535,G52F,-0.07096396,-0.013820836000000001,-0.018118286,-0.247686319,-2.243396686,-0.016991139,-0.070077948,-0.071849971,-0.022227933999999998,-0.017791971,-0.009849700000000001,-0.004414365999999999,-0.031822205,-0.202114679,-0.293257958,-1.588556664,-2.8982367069999997,1.261669133,1.3766186980000001,-8.377659857000001,-7.5536494979999995,-7.743204414,-7.701173645,-7.895915733,-10.994356,-7.578358091,-6.636905811,-11.771916389465332,-11.899802207946777,-11.741402626037598,-10.603997230529785,-10.339324951171875 -536,536,G52I,-0.065158743,-0.087096005,-0.355802644,-1.850621565,-3.029309641,0.048424759000000005,-0.080932764,-0.049384721,0.02651815,-0.044143497000000004,-0.130048513,-0.304647627,-0.406957661,-1.693744671,-2.007498458,-2.580431709,-3.478187573,1.405429449,0.767937278,-8.342276598,-7.669541946,-7.594753548,-7.287010917999999,-8.523553291,-10.63652328,-7.820823138,-6.99200141,-12.595802307128906,-14.609756469726562,-13.11154556274414,-11.5059232711792,-11.347433090209961 -537,537,G52H,-0.075044202,-0.07975103900000001,-0.03525133,-0.035948583,-1.650707599,-0.035912141,-0.09157193699999999,-0.058516465999999996,0.064000705,-0.0013215710000000001,-0.158180507,-8.070000000000001e-05,-0.07042196,-0.0037871009999999997,-0.068110064,-1.4360168690000001,-1.8653983280000002,0.7058332540000001,1.325144169,-5.376852747,-4.926141823,-5.2453886569999995,-5.3051316680000005,-5.53918927,-5.868412315,-5.245564759,-4.166941142,-8.905989646911621,-8.735002517700195,-8.80850601196289,-8.24615478515625,-7.8704915046691895 -538,538,G52K,0.003140753,-0.059740260999999996,-0.010615719,-0.12128259599999999,-1.6790063030000002,-0.002956593,-0.014326261000000002,0.020607767,0.065659698,-0.050033377000000004,-0.069447145,-0.032402119,0.011170682,-0.104205139,-0.13836005199999998,-1.8148009180000002,-1.5432116880000002,1.030317726,1.323075299,-4.312924689,-3.993909683,-4.020330437,-4.442755562,-4.4728763119999995,-4.63475145,-4.3419704789999995,-2.686857259,-7.815228462219238,-10.010126113891602,-8.154375076293945,-8.503677368164062,-7.422796726226807 -539,539,G52M,-0.058545358,-0.022569127,-0.019596767,-0.08402447,-1.645114846,-0.0298781,-0.082441869,-0.034648847,0.016701069,0.007510878,-0.052649132,0.002371624,-0.041565158,-0.08027142599999999,-0.087777513,-1.601920625,-1.688309066,0.8577023220000001,1.326226282,-8.261242461,-7.393528656,-7.481476265,-7.034510704,-8.138826836,-11.25786984,-7.198189641,-6.636905608999999,-11.385845184326172,-11.934185981750488,-11.048762321472168,-9.897238731384277,-10.00723648071289 -540,540,G52L,-0.012440136999999999,-0.019598826,0.007416516,-0.23253181,-1.7372405359999998,-0.012168779,-0.023668024,-0.00121225,-0.008176188000000001,-0.014041591,-0.02515606,-0.006998167,0.021831198,-0.156140096,-0.30892352300000003,-1.72786136,-1.746619712,1.083384718,1.335722885,-6.835377272000001,-5.998673912,-6.164090988,-5.914792792999999,-7.151677841000001,-8.947650826,-6.12304038,-5.109115458,-10.356757164001465,-10.241527557373047,-10.085820198059082,-9.043001174926758,-8.985681533813477 -541,541,G52N,-0.016179965,-0.015956314,-0.001694975,-0.040297307000000004,-0.5645407379999999,-0.066773254,-0.050902375,0.018542446,0.158885754,0.051521137,-0.08343376400000001,0.028827852999999997,-0.032217802000000004,-0.036406108,-0.044188505999999995,-0.49615074200000003,-0.632930734,0.7623519870000001,1.462077457,-2.9940635560000004,-3.450037231,-2.818676483,-3.051779533,-3.559275009,-2.090549522,-3.2632017060000003,-2.151628657,-6.177532196044922,-6.337643146514893,-6.07294225692749,-6.39804744720459,-5.860229015350342 -542,542,G52Q,-0.043054485,0.027510531,-0.004828025,0.016663182,-1.581973632,-0.038198188,-0.047786604,-0.038322366000000004,0.048540575999999995,0.051342847999999996,0.0036782140000000004,0.010680771,-0.02033682,0.049031902999999995,-0.015705538999999998,-1.397277835,-1.766669429,0.616904972,1.320265214,-4.290208435,-3.903479218,-3.9610475689999998,-4.058373238,-4.404859032,-5.123283119,-4.257980327,-3.2721994010000004,-7.149033546447754,-8.132542610168457,-7.154053211212158,-7.567077159881592,-6.742514610290527 -543,543,G52P,-0.031945269,-0.018313373,0.01099754,-1.06203159,-1.923346365,-0.000876739,-0.057458813,-0.006431724000000001,-0.000892616,-0.001431701,-0.035195045,0.030398473999999998,-0.008403394,-0.703383709,-1.420679471,-1.9090610719999999,-1.9376316580000001,1.928080616,1.469151095,-5.095099393,-5.17498925,-3.360198647,-5.118368515,-5.863037376,-5.958903175,-4.855248352,-3.515278934,-10.442103385925293,-13.43147087097168,-10.296957015991211,-10.762279510498047,-7.98599910736084 -544,544,G52S,-0.010350649,-0.019063312,-0.009109004,0.020904795,-1.555244441,-0.049930759000000005,-0.035894959,0.015193661,-0.025542684,0.004021938,-0.042148560999999994,0.005262780999999999,-0.023480788,0.0366098,0.00519979,-1.484761705,-1.625727177,0.76574886,1.3286312040000001,-3.917324789,-4.013838951,-3.549087105,-3.5842398,-4.237189438,-4.202268654,-3.915683562,-3.276713795,-7.812300682067871,-7.678200721740723,-7.703584671020508,-7.400127410888672,-6.522986888885498 -545,545,G52R,-0.0123626,0.021081446,0.014971346000000002,-0.381886376,-2.0423797009999998,-0.01646359,-0.025800267,0.001075068,-0.020902981,0.057772347,-0.015609455,0.00910685,0.020835841,-0.205480352,-0.5582924,-1.667269668,-2.417489733,1.260084795,1.364649007,-4.735410483,-4.36916066,-4.4029808269999995,-4.0396805339999995,-5.053335434,-5.811894959,-4.347794545,-2.95190814,-8.585211753845215,-9.257781028747559,-8.596964836120605,-8.408109664916992,-7.873780250549316 -546,546,G52T,-0.028814535,-0.014915852,-0.011225543000000001,-0.149252886,-1.727659998,-0.00919026,-0.065441242,0.007812173,0.009218691999999999,0.010990568999999999,-0.040822273,-0.024792257999999998,0.0023411729999999998,-0.063936415,-0.234569357,-1.599645636,-1.855674359,0.7800788329999999,1.3204223999999998,-5.1912630889999996,-4.556334015,-4.239205193,-4.469777046,-5.071033997,-7.619965195,-4.898574967,-3.709303017,-9.948598861694336,-10.729798316955566,-9.374025344848633,-9.099185943603516,-8.059526443481445 -547,547,G52W,-0.042030153,-0.024696265,0.002043834,-0.623120863,-1.9843524780000001,0.036422099,-0.035813557999999995,-0.048246748,-0.019851473999999997,-0.049908274,0.0005157440000000001,-0.01428512,0.018372786999999998,-0.456534073,-0.789707652,-1.7909090930000002,-2.177795862,1.662455749,1.427692661,-8.232757307,-7.30501619,-7.8956138,-7.885926544,-8.177372948,-9.899857056,-7.095832497000001,-6.474529788,-12.842623710632324,-14.298508644104004,-12.784921646118164,-12.683094024658203,-12.038881301879883 -548,548,G52V,-0.02586983,-0.010626934,0.028371197999999997,-1.416511474,-2.3233428640000002,-0.002087798,-0.038720869,-0.013018791000000002,-4.26e-05,0.014627688,-0.035881556,-0.019867877,0.07661027200000001,-1.290748217,-1.542274731,-1.989109539,-2.6575761890000003,2.623708565,1.7791195919999998,-7.390353557,-6.924515152000001,-6.261839012,-6.462740662000001,-7.175654076,-10.12701888,-6.929398357,-5.708914425,-11.296911239624023,-13.272848129272461,-11.996649742126465,-10.415202140808105,-9.778106689453125 -549,549,G52Y,-0.108321779,-0.060638248,-0.0009318839999999999,-0.38002932100000003,-2.109773078,-0.0033032829999999997,-0.125178942,-0.091464615,-0.050877544000000004,0.020117239,-0.141393734,0.049043080999999995,-0.050906848,-0.18602398899999997,-0.574034652,-1.486941356,-2.7326048,1.246786733,1.389292094,-8.075219528,-6.914054939,-8.008847435,-7.948563652000001,-7.730641968,-9.773989647,-7.288614875,-6.389109022,-12.199151039123535,-12.13162612915039,-12.272446632385254,-11.231359481811523,-10.79737377166748 -550,550,K53A,-0.009480222,0.001371396,0.009175101,0.020797248,-0.009332043,-0.012781208,-0.004421919,-0.014538525,-0.010372865,0.023404774,-0.020661982,0.029755544,-0.011405343,0.011598056,0.02999644,0.022921597000000002,-0.041585683,1.120589182,2.633820608,-1.677988852,-1.7659964680000002,-1.013070175,-1.538630867,-2.558896904,-1.5133498459999999,-2.764899118,0.296810672,-4.000907897949219,-4.172779083251953,-4.696587562561035,-4.133883953094482,-4.417252540588379 -551,551,K53C,-0.054359667,0.01147139,-0.030007354,0.025694929,-1.3827770819999998,0.07859433,-0.052589045,-0.05613028900000001,0.103453299,0.028625262000000002,-0.005682483,0.019109233,-0.07912394,0.023166858,0.028222999,-1.08560626,-1.679947904,1.0081043570000001,1.397465929,-6.848581253,-6.000081024,-6.299377419,-7.334269577000001,-7.567601882999999,-7.041576363,-7.3468452420000006,-5.379504032000001,-7.9325270652771,-8.935595512390137,-10.621405601501465,-9.10116958618164,-10.980948448181152 -552,552,K53E,-0.057326985,-0.022193405,-0.038447907,-0.038052717,-0.017441508999999997,-0.0064613,-0.072598768,-0.04205520099999999,-0.014469506000000002,-0.033112007,-0.011274801999999999,-0.041761365,-0.035134448,-0.045652713,-0.03045272,-0.006527651999999999,-0.028355365,1.0656663659999999,2.623297486,-2.0756151000000003,-1.912175842,-1.4800440830000001,-3.154644844,-2.446250992,-1.38495974,-2.864317392,0.627909394,-3.055192470550537,-3.8959875106811523,-4.3992156982421875,-3.7183334827423096,-4.237613677978516 -553,553,K53D,-0.0077959019999999995,0.0016050779999999998,0.035474456,0.041011577,0.013371071000000002,-0.018466342,-0.0077972169999999995,-0.0077945869999999995,0.005293256,0.033207337,-0.029997181,0.023242207999999997,0.047706704,0.019959189,0.062063965,0.036301312999999995,-0.009559172,1.259491033,2.8930176839999997,-3.6719566969999997,-2.468883987,-2.6495519869999997,-5.173734314,-4.975590034,-3.092023163,-4.119900862,-0.024595093999999998,-4.379685401916504,-5.696116924285889,-5.921483516693115,-5.189282417297363,-5.665970802307129 -554,554,K53G,-0.041356335,0.01232886,0.02294722,0.032055247,-0.093902637,0.026207282000000002,-0.03984317,-0.042869499000000005,0.034754131,0.050752205999999994,-0.026094486,0.056006943,-0.010112503,0.064342016,-0.000231522,-0.030476666,-0.157328608,1.237023233,2.517427644,-4.675491692,-3.639215332,-3.94985183,-6.313111641,-5.794354706,-3.68092495,-4.650691053,-0.9977324740000001,-5.547311305999756,-7.120133399963379,-6.7844767570495605,-6.023985385894775,-6.928535461425781 -555,555,K53F,0.013198544,-0.00199763,0.024897989,-0.007659326,-0.136761276,0.013997776000000002,0.047869068,-0.021471981,-0.020465021,0.020812491000000002,-0.02480775,0.055591447,-0.00579547,-0.017910577,0.002591926,-0.09609753,-0.17742502100000002,1.3339214,2.2679830880000003,-3.9357891510000003,-2.528354019,-3.14685318,-4.237520851,-5.894870804,-3.8713469010000003,-4.366818806,-1.6743139530000002,-7.413166046142578,-8.670080184936523,-8.94963550567627,-9.011021614074707,-9.358176231384277 -556,556,K53I,-0.059441727,0.007738123,-0.009421033,0.015696018,-0.082011237,-0.033641695,-0.08811808300000001,-0.03076537,0.053599258,0.025798899,-0.010322653000000001,0.018454627,-0.037296692,0.044932335999999996,-0.0135403,-0.017492817,-0.14652965699999998,1.213423602,2.543383438,-3.391903246,-2.93918425,-2.9056680760000004,-4.189300483999999,-4.680452446,-2.244910973,-4.805919927,-2.19597829,-6.302788257598877,-7.334549903869629,-7.38383150100708,-7.769128799438477,-7.238909721374512 -557,557,K53H,-0.065100628,-0.039347872,-0.02010982,0.010362261,-0.066030242,-0.028571457,-0.078964468,-0.051236788,-0.037413018,0.026769837999999997,-0.105465581,0.037938475,-0.078158114,0.021051092999999996,-0.000326571,0.022568928999999998,-0.154629412,1.139088154,2.66526459,-3.233080808,-2.9315330889999998,-3.3338094710000004,-2.617027153,-3.220897263,-4.062137062,-4.464857084,-1.617228506,-5.296795845031738,-5.866957664489746,-6.375990867614746,-5.29371452331543,-6.302241325378418 -558,558,K53M,-0.056733005999999996,0.017320323999999998,0.029322215,0.016302163999999997,-0.025403977999999997,-0.053304177,-0.062466017,-0.050999995,-0.019572908,0.094394415,-0.059753768,0.08794017400000001,-0.029295744,0.043990047000000004,-0.011385718999999999,0.08045969,-0.131267646,1.223759613,2.920356167,-3.3038416930000003,-2.5613128130000002,-3.458778595,-2.699389992,-4.230004951000001,-3.569722115,-4.881024965,-2.7270557460000004,-6.90364408493042,-7.649346828460693,-8.155570030212402,-7.578192710876465,-7.846628665924072 -559,559,K53L,-0.02775355,-0.007413932,0.008486077,0.031747423,-0.033696514,0.0017240729999999998,-0.026813952999999998,-0.028693146,-0.004239953,0.040714184,-0.055542047000000004,0.023775862000000002,-0.006803709000000001,0.041597233,0.021897613,0.014348283,-0.081741311,1.205919363,2.667881045,-2.297924609,-1.143322121,-2.323057243,-1.943709984,-3.252626701,-2.826906998,-4.010577778,-1.255735608,-5.511013507843018,-6.640488624572754,-6.818354606628418,-6.282897472381592,-6.7557148933410645 -560,560,K53N,0.035642862000000004,0.018168551,0.045629047,0.046970097999999995,0.000860667,-0.01870789,0.034037063,0.03724866,-0.08049769,0.019265653,0.017071448,0.042980804000000004,0.048277289,0.021153968,0.072786227,0.024485302,-0.022763969,1.0749744890000001,2.575935085,-2.397261484,-2.125000214,-2.067987778,-2.957359573,-2.22665036,-2.609309494,-3.156693437,-1.196900902,-4.836414337158203,-5.293125629425049,-5.709829330444336,-5.31472635269165,-5.830650329589844 -561,561,K53Q,-0.064467582,-0.040891209,-0.015934848,0.008586940999999999,-0.035956316,-0.017645888000000002,-0.06853149,-0.060403674000000004,0.010390316,-0.014352789,-0.067429629,0.045118060999999994,-0.07698775599999999,0.041913921,-0.024740039,0.026126846000000002,-0.09803947800000001,1.108603588,2.726266873,-0.352964899,-0.344955299,-0.733219315,-0.041185318,-0.50551049,-0.13995407099999999,-0.834224945,-0.085470368,-3.535217761993408,-3.627746105194092,-4.304094314575195,-3.526003122329712,-4.3287858963012695 -562,562,K53P,-0.07645650799999999,-0.014814131999999999,-0.516393098,-1.6302705309999999,-2.375736807,0.051281823,-0.057169639,-0.09574337599999999,0.01044026,0.019469808,-0.049098072,-0.352982313,-0.6798038820000001,-1.494469414,-1.766071648,-1.7736835180000001,-2.977790096,3.5697699430000003,2.5835880159999998,-3.86512625,-3.395563881,-3.914318626,-3.7480929410000003,-4.097907967,-4.169747833,-4.229257076000001,-1.606272485,-8.375664710998535,-10.771379470825195,-8.766119956970215,-8.027129173278809,-8.49155044555664 -563,563,K53S,-0.050495171,-0.013098143000000001,-0.005297299,0.035675001,-0.070319479,0.027581112999999997,-0.054754125,-0.046236217,0.015286283000000001,0.023627841,-0.049824127,0.047895201,-0.058489797999999996,0.063364246,0.007985755,0.008632441,-0.149271398,1.071761897,2.58014253,-2.438742757,-2.611211914,-1.701146332,-2.925926697,-2.755948723,-2.1994801180000003,-3.2078085260000004,-0.987376957,-4.831281661987305,-5.7396697998046875,-5.889467239379883,-5.627302646636963,-5.967185974121094 -564,564,K53R,-0.033126552999999996,-0.005835707,0.018994185,0.034880002,-0.020171097,-0.007097472,-0.053460442999999996,-0.012792663000000001,0.029693907999999998,0.037751621,-0.049423034000000005,0.07115291900000001,-0.03316455,0.058622479000000005,0.011137524,0.049797002,-0.09013919599999999,1.154307607,2.8306437160000004,-1.232863437,-0.42022381600000003,-1.050185966,-0.747173271,-1.543588943,-2.403145187,-2.343706802,0.852563508,-3.8427915573120117,-4.356125831604004,-4.615299224853516,-3.5601563453674316,-4.1092305183410645 -565,565,K53T,-0.047720099999999994,-0.018620372,-0.019365818,-0.004198577,-0.06812083,-0.018669861,-0.057383874,-0.038056325,0.074071227,-0.011596041000000001,-0.025644702999999998,0.009812796,-0.048544431,0.004545693,-0.012942846000000001,-0.028857027,-0.107384632,1.254800696,2.432989606,-1.973463837,-1.965676559,-1.420248367,-2.254488731,-2.4254802090000003,-1.801425316,-3.306855543,-0.7259684940000001,-4.458645820617676,-5.044504642486572,-5.243492126464844,-5.1004438400268555,-5.316905498504639 -566,566,K53W,-0.05888709,-0.030869081,-0.028850659,-0.004639882,-0.735453025,0.043709099,-0.050507579000000004,-0.06726660000000001,-0.029797219,-0.00557943,-0.056158732,0.030685649,-0.088386967,0.027871359,-0.037151122,-0.44310342,-1.02780263,0.824814215,1.5055091180000002,-1.656783841,-0.144984749,-1.519902435,-1.867578491,-2.889898605,-1.861554924,-3.88859761,-1.086243327,-8.204212188720703,-11.09207534790039,-10.244405746459961,-10.105600357055664,-10.104448318481445 -567,567,K53V,-0.07460498,-0.014389252,-0.005017852,0.016363482,-0.041850368,-0.015458567,-0.077946146,-0.071263813,0.048483529000000004,0.045191863,-0.073970367,0.067571733,-0.077607436,0.058003611,-0.025276648,0.033740572,-0.11744130800000001,1.230449126,2.728448111,-2.64824884,-2.044095978,-2.233257408,-2.8145612410000003,-4.28724659,-1.862082985,-3.72701349,-1.313983913,-5.206042766571045,-6.464868545532227,-6.3142852783203125,-6.469358921051025,-6.157422065734863 -568,568,K53Y,-0.046545851,0.012037013999999999,0.031077342,0.040895084,-0.14182017800000002,0.072669371,-0.034756429,-0.058335273,-0.027235548,0.034548816,-0.010474789,0.073665232,-0.011510548,0.062659527,0.01913064,-0.095741332,-0.187899024,1.215013415,2.290331455,-4.683560483,-3.4600743260000004,-4.132097336,-4.862936409,-6.263318732999999,-4.69937561,-4.789992664,-2.160102434,-7.253610610961914,-8.700164794921875,-9.107919692993164,-8.546565055847168,-9.126567840576172 -569,569,I54A,-0.023129063,-0.006890236,-0.0057679540000000005,0.04632831,-0.29747840000000003,0.033000292,-0.012215021000000001,-0.034043104,-0.012621712,-0.006911293000000001,-0.006869178,0.013762576,-0.025298482999999997,0.068074969,0.02458165,-0.199563203,-0.39539359700000004,1.250853078,2.066913331,-2.267246861,-2.957902466,-3.077179306,-1.328187683,-2.018848045,-1.954116806,-2.542771461,0.383157929,-3.902193069458008,-4.279718399047852,-4.505290508270264,-4.6531877517700195,-4.204637050628662 -570,570,I54C,-0.040677477999999996,-0.03869697,-0.031557142999999996,-0.012448513000000001,-1.22733725,0.022304435,-0.030096058999999998,-0.051258897000000005,-0.037283641,-0.047872767000000004,-0.029521172000000002,-0.025268087999999998,-0.037846198,0.017022248,-0.041919274,-0.9667439040000001,-1.487930595,0.804785647,1.3726316719999998,-4.805729349,-4.977004958999999,-5.5922477420000005,-3.9471438830000003,-5.109667084,-4.402583076,-4.537176366000001,-1.941919415,-7.0370988845825195,-7.464582920074463,-7.016263008117676,-7.487072944641113,-8.244129180908203 -571,571,I54E,-0.038754576,-0.01499376,-0.00151274,0.027136531000000002,-0.395029678,0.023081891,-0.02421874,-0.053290412,0.068783407,0.002231621,-0.032219141,-0.00012355799999999998,-0.0029019209999999996,0.06722057299999999,-0.012947512,-0.27491695,-0.515142405,0.743402718,1.5591557809999999,-1.833488882,-1.144862564,-2.6245727690000002,-1.1226017529999999,-1.3315403140000002,-2.9438670119999997,-2.8580017580000003,1.3631383769999998,-3.6493444442749023,-5.025078773498535,-3.4501683712005615,-4.802142143249512,-4.760319232940674 -572,572,I54D,-0.056099368,-0.007939577,-0.021386905,-0.09972308699999999,-1.6067735109999999,-0.021766659,-0.037656155,-0.074542581,-0.008375658000000001,0.014390567,-0.03026972,0.003933364,-0.046707174000000004,0.021273647000000003,-0.220719821,-1.604337277,-1.6092097440000002,0.601184374,1.309185605,-4.692432782,-4.318589478,-6.501045753,-3.7665638280000002,-2.819447647,-6.0565172039999995,-4.568761098,-1.347296878,-6.26521635055542,-7.295955657958984,-6.001346588134766,-7.771634101867676,-7.26417875289917 -573,573,I54G,-0.064542125,-0.014153108000000001,-0.020052259,-1.2325033140000001,-2.112324616,0.045723955999999996,-0.029550329,-0.09953392,-0.033256371,-0.024280022000000002,-0.004026194,-0.018590146999999998,-0.021514371,-0.9391246459999999,-1.525881981,-1.9782857059999999,-2.246363526,2.2071254319999998,1.559193934,-3.690598213,-4.386127693,-4.941524788,-2.67427462,-2.8781355210000004,-3.572928444,-3.56936914,-0.724411576,-5.860966682434082,-7.263416290283203,-6.919139385223389,-7.120235443115234,-7.041202545166016 -574,574,I54F,0.015921842,0.021441281,0.034468634,0.052441101,-0.063526157,-0.026463137,0.021186947999999997,0.010656736000000002,0.007404911,-0.035732059,0.07861462,0.005349171999999999,0.063588096,0.08258377900000001,0.022298422999999998,-0.074300618,-0.052751695,1.4113049519999998,2.545440026,-3.708910501,-3.58673307,-4.461830566000001,-3.2909434510000004,-3.84006131,-3.3649841080000003,-4.16432868,-1.1836828959999999,-6.434025287628174,-5.608804702758789,-5.689943313598633,-7.14794921875,-6.625016689300537 -575,575,I54H,-0.031823121,0.037092671,0.0009152160000000001,0.073679167,-1.122305108,-0.016733451,-0.022512675,-0.041133566,0.029778062999999997,0.11167706300000001,-0.037491722000000005,0.055062555,-0.053232123,0.147215269,0.000143065,-0.9197487540000001,-1.324861462,0.482941623,1.3387003,-4.540031844,-4.0541984630000005,-5.132406357,-3.9160394210000002,-4.330929718,-5.266585258,-3.299079692,-0.7391240840000001,-4.966104507446289,-4.716406345367432,-4.575448036193848,-5.219120979309082,-5.387543201446533 -576,576,I54K,-0.054961239,0.017675841,-0.005080623,0.046059257,-1.522346732,0.050857354,-0.010579405,-0.09934307199999999,0.081414483,0.021503731,0.013847951,0.045432784000000004,-0.05559403,0.089636447,0.0024820660000000002,-1.260824181,-1.783869282,0.667896291,1.331573594,-2.8931396410000003,-3.948876595,-2.323361916,-2.456528549,-2.794453552,-2.942477592,-3.244820655,-0.37122574399999997,-3.547109603881836,-5.469476222991943,-4.6434855461120605,-4.059944152832031,-3.919468879699707 -577,577,I54M,-0.002580459,-0.008294738000000001,0.021083792,0.022339234,-0.0029390379999999997,-0.047335045,-0.017696651,0.012535733,0.020596591,0.000889002,-0.017478478000000002,0.07424481,-0.032077227,0.073127598,-0.028449131000000003,-0.006186008000000001,0.000307932,1.155632099,2.637126711,-1.578486365,-1.949879761,-1.2697004170000001,-1.856499863,-1.445266449,-1.371085335,-2.713101529,-1.371446203,-4.489223957061768,-4.689852714538574,-5.482043743133545,-5.208884239196777,-4.826351642608643 -578,578,I54L,-0.04230915,-0.026016007999999997,-0.014166538000000001,0.032575887000000005,-0.09729412400000001,-0.011744481999999999,-0.040702335,-0.043915965,-0.005682094,0.000416062,-0.052448077,0.026907332000000003,-0.055240407000000005,0.080893247,-0.015741474,-0.066205396,-0.128382852,1.201765173,2.357535951,-0.027791202999999997,-0.104934784,-0.068961151,0.14095536,0.128820366,-0.234835808,-1.361186622,-0.025450677,-3.7597079277038574,-4.575682640075684,-4.219625949859619,-4.149714469909668,-3.9734416007995605 -579,579,I54N,-0.027288073,-0.0038368820000000002,0.017648614,0.036042556,-1.6807095969999999,0.017065763,-0.015296158999999998,-0.039279986,-0.015288952,-0.028626322000000003,0.020952559,0.065891453,-0.030594226000000002,0.11125923,-0.039174118,-1.591052382,-1.7703668119999998,0.456891098,1.306335875,-3.873269955,-3.7058824919999998,-4.78084462,-3.456992767,-2.525085762,-4.8975441360000005,-3.553138795,-1.060508641,-5.153633117675781,-6.220003604888916,-5.249582767486572,-5.91640567779541,-5.5548095703125 -580,580,I54Q,-0.058182689,-0.032744167000000005,-0.0010353580000000001,0.037605257999999996,-0.8664619440000001,0.020938274,-0.055347837000000004,-0.06101754,-0.021254653999999998,-0.027866815,-0.037621518,0.010586818000000001,-0.012657533,0.052196677999999996,0.023013838,-0.574913876,-1.158010012,0.7451987659999999,1.433223734,-2.902590553,-2.931452034,-3.315317421,-2.3400285640000003,-2.390098625,-3.5360561219999997,-3.6157452589999997,0.107905765,-2.9160280227661133,-4.079563140869141,-3.1131157875061035,-3.059570550918579,-3.8008193969726562 -581,581,I54P,-0.044711657,-0.010474349,0.010979218999999998,0.030636418999999998,-0.9908001759999999,0.02849679,-0.039675768,-0.049747546,0.007678334,0.003458245,-0.024406942,0.048661647999999995,-0.02670321,0.083699466,-0.022426627999999997,-0.7688141559999999,-1.212786196,0.703797837,1.38428326,-5.194536037,-4.761108719,-5.4212813870000005,-4.886559425,-5.509677406000001,-5.394053246,-4.795443756,-1.303730615,-4.103939533233643,-6.3486785888671875,-5.016289710998535,-5.509115219116211,-5.873213291168213 -582,582,I54S,-0.081304748,-0.019553986000000002,-0.025621694,0.007173218,-1.302305709,0.022727181000000003,-0.072305048,-0.090304447,0.08487242800000001,0.019342173,-0.058450144,0.020961979,-0.07220536599999999,0.09607506,-0.081728625,-1.095735628,-1.50887579,0.8359607929999999,1.365554163,-1.984482954,-2.003571884,-2.631519249,-1.599689621,-1.59644532,-2.0911886980000003,-2.195178775,1.001114195,-3.167912006378174,-4.036290168762207,-3.4521429538726807,-4.050219535827637,-3.8064942359924316 -583,583,I54R,-0.070541357,-0.022241652999999997,-0.015986349,0.022199842,-1.209600931,0.015964767,-0.043472893,-0.09760982,-0.037402063,0.005488925,-0.04997223,0.042616905,-0.074589603,0.090810106,-0.046410422,-0.787272462,-1.6319294,0.476593724,1.3461328769999998,-2.6785150730000002,-2.7120962680000003,-2.7629399489999997,-1.8107046740000001,-3.083763298,-3.023071175,-2.777154354,0.791897016,-3.033020496368408,-4.929393768310547,-4.106088638305664,-3.443206310272217,-3.3598573207855225 -584,584,I54T,0.00801054,0.000297606,0.01587093,0.065095842,-0.017431717,-0.004542954,0.000210475,0.015810604,-0.020010752,0.008671234,-0.008076021999999999,0.016806019,0.014935841000000002,0.077923265,0.052268419,-0.029351006000000002,-0.005512428000000001,1.361151851,2.6363844690000002,-0.68440593,-1.317123375,-1.944217659,0.356044594,-0.24418115199999998,-0.272552055,-1.7184457469999999,1.797220981,-1.7892905473709106,-2.750467300415039,-2.19205904006958,-2.2510743141174316,-2.3957102298736572 -585,585,I54W,-0.148268344,-0.030851699,-0.03509277,0.023610867999999997,-0.33586407,-0.01612227,-0.059334843,-0.237201844,0.0072420769999999995,-0.019170533,-0.042532864000000004,0.006036301,-0.076221841,0.058713405,-0.01149167,-0.232936559,-0.43879158100000004,1.3275259959999999,2.026920352,-4.834102219,-4.479171043,-6.1401099089999995,-3.8614246060000004,-4.615488319,-5.074317215,-4.2255681339999995,-1.918368784,-6.947225570678711,-7.161490440368652,-6.9222259521484375,-7.923679351806641,-8.025781631469727 -586,586,I54V,-0.020032888000000002,-0.002041864,0.025395617000000002,0.068283713,0.054009757,-0.01513863,-0.034581529,-0.005484246999999999,0.0034480440000000004,0.02362648,-0.027710207,0.082294178,-0.031502944,0.12558349800000002,0.010983927,0.08465570900000001,0.023363804,1.1275347009999999,2.9638930930000003,-0.106620937,-0.059003799,-0.536916435,0.256526619,-0.192865402,-0.000845665,-1.7890680819999998,0.40249451299999994,-2.509385585784912,-2.3253636360168457,-2.8490028381347656,-2.6993072032928467,-2.8435916900634766 -587,587,I54Y,0.0008938660000000001,0.000170567,0.041784093,0.05155287099999999,-0.862369383,-0.047665091,-0.008414305,0.010202036,0.02026095,0.033811189,-0.033470055,0.100694486,-0.017126301,0.108501919,-0.005396176999999999,-0.668245723,-1.056493042,0.477423959,1.360606119,-4.615511594,-4.280406967,-5.684105682,-3.988009659,-4.415904877,-4.709130783,-3.519965169,0.070656499,-6.200507164001465,-5.115478515625,-5.737894535064697,-7.309696197509766,-6.971179962158203 -588,588,L55A,-0.043946162000000004,-0.000406832,-0.017659964,-0.04864870599999999,-1.6201674590000001,-0.018545564,-0.022917889,-0.064974435,0.032860316,0.02843301,-0.029246674,0.001784491,-0.037104418,-0.016624178,-0.080673233,-1.423148544,-1.8171863730000002,0.7382433629999999,1.332343679,-3.4091377819999997,-2.092425934,-6.364892265,-3.681854874,-2.750774101,-2.155741737,-3.549245343,-1.0053076570000001,-4.905901908874512,-8.352188110351562,-3.8042855262756348,-5.165691375732422,-5.94684362411499 -589,589,L55C,0.028029462999999998,0.001886246,0.002193797,-0.00701446,-1.470231069,0.048476978,0.06000908,-0.003950154,0.014303419,-0.05532243,0.059094922,0.052632139,-0.048244546,0.062222867,-0.076251787,-1.393185321,-1.5472768159999999,0.247100085,1.304887879,-6.663730322,-6.1453296129999995,-7.441542168,-7.006262711000001,-5.6897113720000005,-7.035805748,-5.63049685,-3.7217091410000003,-8.127453804016113,-8.821446418762207,-7.557713508605957,-8.895750045776367,-9.400945663452148 -590,590,L55E,-0.078308734,-0.011803781999999999,-0.017035184,-0.062833403,-1.114443659,0.019067549,-0.08280446799999999,-0.073812999,0.072972759,-0.044920472,0.021312908,-0.011197608000000001,-0.022872759,-0.07971439999999999,-0.045952405,-1.00598219,-1.222905128,0.95321184,1.39677537,-6.569337236,-6.498293045,-8.704575347999999,-7.190007866,-5.440958405,-5.012851517,-5.185668956000001,-4.339928325,-7.299602031707764,-11.032181739807129,-7.174590110778809,-6.992412090301514,-8.098011016845703 -591,591,L55D,-0.097568585,0.007447266,-0.009581961,-1.194058291,-2.571945359,-0.028671237000000002,-0.077885283,-0.117251887,0.039101927,0.019593289,-0.004698758,0.012425044,-0.031588966,-0.779251136,-1.608865445,-2.166373152,-2.977517565,1.839895064,1.374642484,-7.316120255,-6.170497795,-11.01929231,-7.7257506639999995,-5.85398597,-5.811074532,-5.712419656000001,-4.416674351,-8.313815116882324,-11.333683013916016,-8.417465209960938,-7.680633544921875,-9.013229370117188 -592,592,L55G,-0.062744679,0.004591223,-0.002486328,0.009567455,-1.61012303,0.039326442999999996,-0.040691204,-0.084798153,0.024217107,0.018148048,-0.008965603,0.048985457,-0.053958112999999995,0.05550795,-0.03637304,-1.60504985,-1.615196209,0.554420618,1.3082232059999999,-7.622554494,-7.020751228,-9.847201842999999,-8.187922455,-6.942603996,-6.114292946,-6.166130805,-5.051864209,-7.748858451843262,-10.128183364868164,-6.763881206512451,-7.261928558349609,-7.379796504974365 -593,593,L55F,0.029728566,0.054367623,-0.018843382,0.0016532089999999999,-0.209352289,-0.02730735,0.030207291,0.02924984,-0.00044593599999999997,0.004441945,0.10429330099999999,-0.06297349299999999,0.025286728999999997,-0.053825168,0.057131585,-0.18810131,-0.230603267,1.495308765,2.191795125,-2.765576958,-2.179935318,-3.14322728,-4.269937363,-2.375571709,-1.85921312,-4.093077741,-0.618096223,-4.7318878173828125,-5.440033912658691,-5.054838180541992,-5.5828986167907715,-6.0359015464782715 -594,594,L55I,0.015801092,0.025449447000000004,0.017765421,0.038509523,-0.013824586000000002,-0.0004903290000000001,-0.012705896999999999,0.044308081,0.13521373,-0.06088898,0.11178787300000001,-0.011163983,0.046694824,0.015873963,0.061145082,-0.02845489,0.0008057180000000001,1.18803743,2.483375335,-2.124960611,-2.02143103,-4.005187439,-2.734849815,-1.3058075409999998,-0.557527229,-3.131091544,-0.09901524800000001,-3.343536376953125,-5.209888458251953,-2.644421100616455,-3.7150630950927734,-4.238204002380371 -595,595,L55H,0.01967476,0.024327373,0.034673711,0.011815338,-0.720452442,-0.002208673,0.05921104,-0.01986152,-0.027649987999999997,0.017525046000000002,0.031129699,0.06325662900000001,0.006090791999999999,0.029038291,-0.005407615,-0.510697338,-0.9302075459999999,0.522433189,1.390179118,-4.991145511,-3.741222977,-6.098104919,-6.061464691,-4.680322037,-4.37461293,-4.816604959,-3.581706595,-5.510950088500977,-7.289702415466309,-5.672816753387451,-6.281158447265625,-7.3053412437438965 -596,596,L55K,-0.016362383,0.062781488,0.066615652,-0.005006381,-0.8061271990000001,-0.006896957,-0.035483519,0.0027587540000000004,0.021047552,0.05680163,0.068761346,0.067074075,0.066157229,0.029550235,-0.039562996,-0.599181824,-1.0130725729999999,0.684510944,1.412167555,-7.41201237,-7.192982109,-9.069798279,-6.974298843,-6.025270821,-7.7977118,-7.04608472,-5.444832432,-7.421029090881348,-8.72409725189209,-5.820350646972656,-7.510620594024658,-7.809609413146973 -597,597,L55M,-0.048998703,-0.017679516,-0.054487304,-0.027730247000000003,-0.067702575,0.030070307,-0.038735289,-0.059262116,0.18498755100000003,-0.0811261,0.045767068,-0.001968984,-0.10700562400000001,-0.039165036,-0.016295457,-0.014880276000000001,-0.120524873,1.1943883579999999,2.506278758,-3.580665215,-3.744216919,-3.848321495,-4.021985176,-3.430395683,-2.858406799,-4.156214179,-2.71152068,-6.951362609863281,-7.145537853240967,-6.374391555786133,-6.793609619140625,-6.428817272186279 -598,598,L55N,-0.004519032,0.047251744000000005,0.010384456,0.008009066,-1.5260329819999998,0.028973415,-0.0030450790000000004,-0.005992984,-0.012879236,0.054138411,0.040365077,0.032661058,-0.011892146999999999,0.013695243999999999,0.002322888,-0.949487822,-2.102578141,0.707327327,1.3600755430000002,-7.07943243,-6.9605602189999995,-8.420739624,-7.976489432999999,-5.883748665,-6.155624207000001,-6.339875677,-5.494911913999999,-7.2043375968933105,-9.809514045715332,-7.102790355682373,-7.230152130126953,-8.494916915893555 -599,599,L55Q,-0.030800542,0.073817553,-0.011402408000000001,0.025562421000000002,-1.22558591,0.038036572000000005,-0.001181516,-0.060419568,-0.00729134,0.08708017900000001,0.060554927,0.039538207,-0.062343022000000005,0.020181424,0.030943417999999997,-0.8573665229999999,-1.593805296,0.8796129220000001,1.405673265,-5.237211339,-5.143525718999999,-6.653509102,-5.608140113999999,-4.085807777,-4.695073982,-5.20501748,-4.156817107,-6.579073905944824,-8.19696044921875,-6.265783786773682,-6.151926517486572,-7.028839111328125 -600,600,L55P,-0.020048331000000003,-0.073588737,-1.459205261,-2.0948967119999997,-2.6049618430000003,0.024842976,0.025423424,-0.06552008599999999,0.022889362000000003,-0.043335947,-0.10384152599999999,-1.433859114,-1.4845514080000002,-2.059534637,-2.1302587859999997,-2.401333674,-2.808590012,2.9376147460000004,1.3539900180000002,-8.306996106,-7.403308128,-10.43497247,-7.890239769,-7.440086792000001,-8.366373367000001,-6.456354577000001,-4.046014867,-9.052919387817383,-9.816463470458984,-9.181734085083008,-9.597614288330078,-9.244014739990234 -601,601,L55S,-0.065589886,-0.0031687259999999997,0.004811972,-0.030178609,-2.0217628519999997,0.001485089,-0.046266743,-0.084913029,0.01036546,-0.022642047999999998,0.016304596,0.035720926,-0.026096982999999997,0.004298917,-0.064656135,-1.523067271,-2.520458432,0.654592339,1.3169220590000001,-4.876852455,-4.213934975,-5.719207542,-6.152587685,-4.4469653319999995,-3.8515667419999997,-4.6263844480000005,-3.3798825910000003,-5.719146251678467,-8.22033977508545,-4.69748592376709,-5.375679016113281,-6.591957092285156 -602,602,L55R,-0.010344306999999999,0.011764166999999999,0.028966117000000003,-0.007640521,-0.520211329,-0.004925605,0.00045368199999999996,-0.021142296,0.020842744,-0.0073620180000000006,0.030890351,0.049785939,0.008146295,-0.001863043,-0.013417999,-0.304533103,-0.7358895540000001,1.09015979,1.7443538809999999,-4.144089966,-3.55778981,-4.818662918,-4.186270409,-3.938962296,-4.218764397,-4.084569518,-3.903406227,-6.255308628082275,-6.298512935638428,-4.996606349945068,-6.298006057739258,-6.473337173461914 -603,603,L55T,-0.017072321,0.009161770999999999,0.004390845,-0.019588093,-0.997385307,0.005182841,-0.029033215,-0.005111427,0.011094963999999999,-0.012541387,0.030864929,0.020994421,-0.012212731999999999,-0.007400788,-0.031775397999999996,-0.586842842,-1.4079277719999999,0.8429768,1.453456549,-3.487301445,-3.175902016,-4.7275237269999995,-4.080710945,-2.831628395,-2.6207421419999997,-2.9034654460000002,-2.497732234,-5.439836502075195,-8.117801666259766,-4.672107696533203,-4.900594234466553,-6.096207141876221 -604,604,L55W,-0.060346077000000005,0.047085735999999996,0.03714705,-0.014491091999999999,-1.28202634,-0.018202402,-0.07058695599999999,-0.050105198,-0.002847116,0.06603796599999999,0.028133506000000003,0.06257607700000001,0.011718023000000001,-0.024152102999999998,-0.004830081,-1.172978518,-1.391074161,0.521021073,1.3252469,-2.6874552869999997,-1.47247052,-4.4868185039999995,-2.8225795060000003,-2.637441612,-2.017966293,-2.797015375,-1.058120958,-6.9501447677612305,-7.5887250900268555,-7.192193031311035,-7.436026096343994,-8.162010192871094 -605,605,L55V,0.014991166,0.081244323,0.060572757000000005,0.02313431,-0.049845220999999995,-0.004909117,-0.022182547,0.052164878,0.036503158,0.081558681,0.080929965,0.096029484,0.025116028999999998,0.016275226,0.029993394,-0.043165458,-0.056524984,1.3653693869999999,2.637889291,-2.595099638,-1.768907814,-4.709221512,-3.308373581,-2.097502167,-1.091493118,-2.271989622,0.353714244,-3.534435749053955,-6.575422286987305,-2.860293388366699,-4.257411003112793,-4.95197868347168 -606,606,L55Y,-0.019376263,0.00380908,0.036430463999999996,-0.005424249,-0.120999362,-0.016813688,-0.027238701,-0.011513825,0.048041515,0.017675425,-0.010057266,0.063475005,0.009385922,-0.0077433630000000005,-0.0031051340000000003,-0.08477337199999999,-0.15722535099999999,1.272755985,2.290210922,-4.279370291,-3.188171608,-4.103879044,-5.847480469,-3.707082947,-4.550237388999999,-4.011470481,-1.385643533,-5.410098552703857,-6.305087089538574,-6.178889751434326,-6.699880599975586,-7.379256725311279 -607,607,E56A,-0.007075149,-0.045329982000000005,-0.048318462,-0.013853826999999999,-0.087059359,-0.024787014,-0.019267115,0.0051168179999999995,0.15445273699999998,-0.055201609000000006,-0.035458355,-0.084661397,-0.011975527,-0.07102575,0.04331809599999999,-0.137520327,-0.03659839,1.411536598,2.222463606,,,,,,,,,-2.0061681270599365,-5.847568511962891,-3.0530660152435303,-5.0933732986450195,-4.154232978820801 -608,608,E56C,-0.105680933,-0.043289752,-0.104420778,-0.107748186,-1.5553789180000002,0.07930635,-0.10360573699999999,-0.107756129,0.033998367,0.007584677,-0.09416418,-0.082322322,-0.126519233,-0.063211844,-0.152284527,-1.485573511,-1.6251843240000001,0.8526084309999999,1.33210435,,,,,,,,,-7.042774200439453,-10.147672653198242,-7.638701438903809,-8.946551322937012,-9.060551643371582 -609,609,E56D,0.049706364,-0.001656966,-0.02204443,0.01783075,-0.058707709000000004,-0.033508049,0.047752800000000005,0.051659928,0.012560391,0.01139915,-0.014713081000000001,-0.058771828,0.014682968000000001,-0.020242648000000002,0.055904148,-0.061992153,-0.055423265,1.440886626,2.531283859,,,,,,,,,-4.255860328674316,-5.52651309967041,-3.9385111331939697,-4.581431865692139,-4.276083946228027 -610,610,E56G,0.013852202,-0.037260837000000005,-0.04457583,0.022340571,-0.051919235,-0.014671097,0.004696482,0.023007922000000004,0.146940447,-0.045369904,-0.02915177,-0.10263316900000001,0.013481509,-0.019784094,0.064465236,-0.06930033599999999,-0.034538134,1.174965431,2.220837145,,,,,,,,,-2.4588782787323,-4.848011016845703,-3.8959124088287354,-4.436746597290039,-5.146963119506836 -611,611,E56F,-0.014309734,-0.022002683,-0.040042314,-1.272702414,-2.4408351880000003,-0.042179322000000005,0.00312856,-0.031748028,-0.021471825,-0.016889803999999998,-0.027115562000000003,-0.05630751,-0.023777118,-0.844470432,-1.7009343959999998,-2.320253123,-2.561417252,1.88586285,1.321685566,,,,,,,,,-5.1202545166015625,-9.107269287109375,-5.575919151306152,-8.29992961883545,-8.806950569152832 -612,612,E56I,-0.011515885,-0.047164517999999996,-0.045670434,-0.753472666,-2.18407722,-0.022711535,-0.009558315999999999,-0.013473454,0.0016950939999999999,-0.037919853999999996,-0.056409180999999996,-0.111194924,0.019854056000000002,-0.524001804,-0.982943528,-1.895568781,-2.472585659,1.7133016719999998,1.4071078190000001,,,,,,,,,-5.038455486297607,-9.627859115600586,-7.029335975646973,-8.486677169799805,-7.98860502243042 -613,613,E56H,-0.070809657,-0.063213294,-0.092155841,-0.05192433900000001,-1.177880662,-0.0177034,-0.06433672,-0.07728259400000001,0.045289532,-0.007392224,-0.119034364,-0.061103452999999995,-0.123208229,-0.047572653,-0.056276025,-0.899108727,-1.456652597,0.752424048,1.376908649,,,,,,,,,-3.71875,-6.222577095031738,-3.1154868602752686,-6.553277015686035,-5.7842583656311035 -614,614,E56K,0.015647325,0.007614162,-0.020991929,0.011995589,-0.101755554,0.006501686,0.016416933999999998,0.014877715,0.048776654,-0.002774055,0.018002379,-0.029402852,-0.012581006,-0.05459101,0.078582188,-0.14131897699999998,-0.062192131,1.438046943,2.254842547,,,,,,,,,-4.759299278259277,-7.8663105964660645,-5.3802642822265625,-7.991220474243164,-6.183267593383789 -615,615,E56M,-0.06796353599999999,-0.059961332,-0.067191928,-0.012326941999999999,-1.303131735,-0.003275111,-0.070221294,-0.06570577799999999,0.176413373,-0.009629253,-0.110293411,-0.08322919999999999,-0.051154656,-0.00150631,-0.023147574,-1.205562615,-1.400700855,0.8889784740000001,1.360993919,,,,,,,,,-5.6446733474731445,-9.274481773376465,-7.3560004234313965,-8.443182945251465,-8.241255760192871 -616,616,E56L,-0.029492049,-0.028623201,-0.02261759,0.006626346,-1.3142741740000001,-0.006761121,-0.022822400000000003,-0.036161698,0.06423704400000001,0.006708924000000001,-0.06395532599999999,-0.034685753,-0.010549427,-0.014150613999999999,0.027403305,-1.023143044,-1.605405304,0.735594566,1.358527951,,,,,,,,,-3.9652934074401855,-7.582019329071045,-5.449731826782227,-7.403896331787109,-7.34169340133667 -617,617,E56N,-0.061491337,-0.099418736,-0.029372517999999997,-0.008609457,-0.101191244,-0.05807229,-0.083730081,-0.039252592999999995,0.055156435999999996,-0.045307234,-0.15353023699999999,-0.002892315,-0.055852720999999994,-0.010367395,-0.006851519,-0.078147535,-0.124234952,1.30780079,2.3325750419999998,,,,,,,,,-4.2580766677856445,-7.741912841796875,-5.0957350730896,-6.381031036376953,-5.5961127281188965 -618,618,E56Q,-0.068666217,-0.070112779,-0.09635936,-0.033419067999999996,-0.13106595099999999,-0.042763784000000006,-0.074507563,-0.06282487099999999,0.11004822,-0.040794858999999996,-0.099430699,-0.10880083199999999,-0.083917887,-0.043994499000000006,-0.022843636,-0.126039188,-0.136092714,1.367618085,2.189172252,,,,,,,,,-3.6979918479919434,-5.376865863800049,-3.9201157093048096,-5.6240034103393555,-4.989368915557861 -619,619,E56P,-0.012698869,-1.267404922,-2.061123294,-2.326231925,-2.66658801,0.01438047,0.017659253,-0.043056990999999996,0.034611594,-1.152267954,-1.382541889,-2.257040859,-1.865205728,-2.032429493,-2.620034356,-2.5182805790000002,-2.81489544,0.24743072,-0.718369061,,,,,,,,,-7.340884685516357,-11.413032531738281,-6.796843528747559,-9.012685775756836,-8.78573226928711 -620,620,E56S,-0.0007111330000000001,-0.017403851,-0.041781813,0.015782653,-0.092556475,-0.028021957000000004,-0.0073836480000000005,0.0059613819999999994,0.064406007,0.008578458,-0.04338616,-0.053848953,-0.029714672,-0.010584885,0.042150191,-0.099030323,-0.086082627,1.238890577,2.226796056,,,,,,,,,-2.3151886463165283,-6.5092620849609375,-3.6385445594787598,-4.94533634185791,-4.601104736328125 -621,621,E56R,0.011447021000000002,-0.006710533,-0.029918322999999997,-0.026677064,-0.221984209,-0.009670920999999999,0.027226742999999998,-0.004332702,0.027233921,0.009520699,-0.022941765,-0.040526953,-0.019309693,-0.049998792,-0.0033553359999999996,-0.22873327699999998,-0.21523514100000002,1.3376358940000002,2.005808318,,,,,,,,,-4.5115065574646,-7.520854949951172,-5.298994064331055,-7.679681777954102,-6.7101969718933105 -622,622,E56T,-0.020475445,-0.038487431,-0.028395944,-0.0009677689999999999,-0.103973384,-0.08167141,-0.039240654,-0.001710235,0.067373955,-0.003981772,-0.07299309,-0.016308431,-0.040483457,-0.009082046,0.0071465090000000005,-0.08323749400000001,-0.12470927400000001,1.36053415,2.349029252,,,,,,,,,-3.259427785873413,-6.802419185638428,-4.175301551818848,-4.508192539215088,-4.688778877258301 -623,623,E56W,-0.014720088000000001,-0.046734505999999995,-0.201240581,-0.649261405,-2.094695901,0.024715932000000003,0.026222512000000003,-0.055662687999999995,-0.011487603999999998,-0.144791744,0.051322732999999995,-0.30159364899999996,-0.100887512,-0.498586209,-0.7999366,-1.8472641019999998,-2.342127699,1.8957620309999998,1.487995674,,,,,,,,,-6.963552474975586,-10.271284103393555,-6.624719142913818,-9.596484184265137,-10.645626068115234 -624,624,E56V,-0.04984681,-0.044497681,-0.042798562000000005,-0.001796628,-1.128714536,0.017311442,-0.038936269,-0.060757350999999994,0.070317786,0.000519606,-0.08951496699999999,-0.030148132999999997,-0.055448990999999996,-0.019360477,0.015767222,-0.960312342,-1.29711673,0.784033348,1.37230954,,,,,,,,,-4.111912250518799,-8.409147262573242,-5.714842319488525,-7.413929462432861,-6.371970176696777 -625,625,E56Y,-0.043523652,0.025877865,0.017042042,-0.34963870799999996,-1.791599132,0.042423775999999996,-0.03035837,-0.056688933,0.059616927,0.046011240999999994,0.005744488000000001,-0.005103774,0.039187858,-0.26831350800000003,-0.43096390700000003,-1.745390669,-1.837807595,1.349598916,1.370011459,,,,,,,,,-5.401338577270508,-8.904703140258789,-4.578409194946289,-7.898034572601318,-8.696805953979492 -626,626,S57A,0.036340484,-0.004586517,0.03007834,-0.000883725,0.025721015,0.031624471,0.016102774,0.056578194000000005,-0.035629375,-0.026064197999999997,0.016891164,0.0061413019999999995,0.054015377999999996,-0.01946162,0.017694171,-0.046749139,0.09819116800000001,1.3799258859999999,2.505310835,-1.377781865,-1.099274887,-1.993630531,-0.524309174,-1.127201965,-2.144492767,-2.7231057919999997,0.122921169,-3.8133091926574707,-4.172216415405273,-3.8755574226379395,-4.842354774475098,-4.218328475952148 -627,627,S57C,-0.115665714,-0.013955769,-0.051785959000000006,-0.057806418,-1.504226134,0.145683596,-0.072253158,-0.159078269,0.111166846,-0.050212967000000004,0.02230143,-0.011094171000000002,-0.092477747,-0.065923019,-0.049689817000000004,-1.27294584,-1.7355064269999998,0.916078152,1.357990546,-5.841583999999999,-4.677781075,-6.4557481,-5.122833244,-6.9841106029999995,-5.967446976000001,-6.178315284,-2.993184007,-8.906631469726562,-8.864496231079102,-8.74123764038086,-9.114938735961914,-7.378477096557617 -628,628,S57E,0.043007582999999995,-0.05173617900000001,-0.02321338,-0.024460533,0.005882297,0.051438362,0.095171462,-0.009156296,0.034711129,-0.106342874,0.002870517,-0.031076852999999998,-0.015349906000000002,-0.047930787999999995,-0.000990277,-0.054090072999999995,0.06585466599999999,1.457366753,2.562356699,-2.615928589,-1.282341995,-1.852585655,-3.476698189,-3.3186020810000003,-3.1494150239999996,-3.940574859,-0.838964677,-4.0537919998168945,-5.434041976928711,-5.20758581161499,-6.853848934173584,-5.404160976409912 -629,629,S57D,0.012117977,-0.025854207999999997,-0.014948584,-0.018968414,-0.976962278,0.144862333,0.027780004,-0.003544051,0.016151053000000002,-0.04325458099999999,-0.008453834,-0.057893672,0.027996505,-0.06153611,0.023599283,-0.661296904,-1.2926276509999999,0.8754014000000001,1.444372617,-3.4851503189999997,-2.612180962,-2.765914429,-3.857658485,-3.424132568,-4.76586515,-4.421185363,-1.068017849,-5.020534038543701,-6.637755393981934,-5.962881088256836,-7.092492580413818,-6.236417293548584 -630,630,S57G,0.02325097,0.026386692000000003,-0.017013241999999998,-0.019903022,-0.036135834,0.076971864,0.026333981,0.020167958,0.048034275999999994,-0.052249883,0.10502326599999999,-0.041878833,0.007852349,-0.0497311,0.009925056,-0.08796653800000001,0.015694871000000003,1.353534257,2.300723294,-0.9383417940000001,-0.746865417,-1.29488813,-0.613921997,-0.63042868,-1.4056047440000001,-1.83041303,0.22230893,-3.1546056270599365,-4.5396223068237305,-4.294859886169434,-4.370080471038818,-3.879183053970337 -631,631,S57F,-0.00194961,0.013476406000000002,0.051840073,0.015182699,-0.258372422,0.008782859,0.016264959,-0.020164178,0.046427148,-0.0041582,0.031111012,0.053146407,0.050533739,0.02456273,0.005802668,-0.19523437899999999,-0.321510465,1.265665564,2.023197908,-5.73285892,-3.422742661,-5.787638306,-5.219929939,-7.156373909,-7.077609787,-5.429482613999999,-2.23125306,-7.434142112731934,-7.212745666503906,-8.209615707397461,-7.882132530212402,-6.615145683288574 -632,632,S57I,-0.039722372,-0.033439109,-0.039665635,-0.033138512,-1.225007314,0.087657125,0.030985571,-0.110430315,-0.13053019800000001,-0.052825847999999995,-0.01405237,-0.020779534,-0.05855173599999999,-0.053164275,-0.013112748,-1.1330645990000001,-1.316950029,1.062855707,1.4032063830000001,-7.176854854,-5.531678597000001,-8.303977844,-6.163407082000001,-8.382250053,-7.5029606929999995,-6.289185336,-3.797157595,-7.865915775299072,-8.026617050170898,-8.440707206726074,-8.200799942016602,-6.86775541305542 -633,633,S57H,0.010871542,-0.014677906000000001,-0.000915884,-0.007518133000000001,-0.200224732,0.031863932000000005,0.03318333,-0.011440246000000001,0.083583325,-0.017047206999999998,-0.012308603999999999,-0.043106757999999995,0.04127499,-0.015843753999999998,0.000807488,-0.164247487,-0.236201976,1.339313391,2.117806775,-4.453052979,-3.345781906,-4.532512665,-4.764303871,-4.443329887,-5.179336563000001,-4.356326686,-2.571637151,-5.865052223205566,-4.583793640136719,-4.995455265045166,-5.437896251678467,-4.369868755340576 -634,634,S57K,0.031551834,0.015012525,-0.008086395,0.013220865,-0.040180196,0.049263309000000005,0.046846961,0.016256707,-0.001339926,-0.014531819,0.044556868,0.0033631190000000004,-0.019535909,0.00751213,0.018929599,-0.10380244300000001,0.023442051000000002,1.386744168,2.3977383530000003,-5.076596799,-4.708790337,-4.992588829,-4.516917068,-6.415753562999999,-4.748934196,-4.945336455,-2.548374021,-7.413156032562256,-7.325196266174316,-6.219435691833496,-7.562922477722168,-5.214169502258301 -635,635,S57M,-0.091014005,-0.07920851,-0.039079847,-0.072252579,-0.128876766,0.048469955,-0.093113885,-0.088914124,0.049035021,-0.093529427,-0.06488759200000001,-0.055705927,-0.022453766,-0.039905012999999996,-0.104600144,-0.117889867,-0.139863664,1.507092754,2.379889094,-6.463851407999999,-5.368222946,-6.463892723,-5.281755821,-7.80404232,-7.401343231,-6.3925078310000005,-3.028457468,-7.972255229949951,-8.21312427520752,-9.093023300170898,-8.819310188293457,-6.305211067199707 -636,636,S57L,-0.007037969,-0.008045191,-0.008061671,-0.010023526,-0.638674441,0.032398866,0.038249579,-0.052325515999999996,0.06271173599999999,-0.018508382,0.002418,0.0050217890000000005,-0.02114513,-0.015982155,-0.004064896,-0.45213098799999996,-0.825217894,0.920949279,1.5257893040000001,-4.97456615,-3.056441925,-4.656159263999999,-3.794424751,-7.705344902,-5.660459907999999,-4.680247137,-1.36518123,-6.9775710105896,-7.551713943481445,-7.260201454162598,-8.065028190612793,-5.0431976318359375 -637,637,S57N,-0.025358027,-0.017188854,-0.019736103999999997,-0.019631752,-0.340335844,0.045646190999999996,-0.0020494289999999997,-0.048666625,0.0624721,-0.011587857,-0.02278985,-0.01149832,-0.027973887000000003,-0.014710408000000001,-0.024553095,-0.232219919,-0.448451768,1.146066182,1.844217246,-3.282030991,-3.242335609,-3.457667831,-3.6026700519999997,-2.677920578,-3.429560883,-3.8422411430000003,-1.655055995,-5.652824401855469,-5.858241081237793,-5.233823776245117,-5.519692420959473,-4.261150360107422 -638,638,S57Q,0.048736563,-0.029655163999999998,-0.032662049,-0.016072632,-0.014098500000000002,-0.023760242999999997,0.050507502,0.046965623,0.017934315,-0.077683923,0.018373596000000002,-0.03736447,-0.027959627999999997,-0.04862179,0.016476527,-0.053721881,0.025524882000000002,1.406656401,2.445028632,-3.380341451,-2.33595459,-2.9788419110000004,-3.705413445,-3.813675407,-4.067821899,-3.9372041810000002,-1.551160695,-4.485134124755859,-4.569319725036621,-3.8213517665863037,-4.67138671875,-4.2620463371276855 -639,639,S57P,-0.039144589,-0.011819021,-1.32400264,-2.119650989,-2.61056601,0.051998947999999996,-0.007547331,-0.070741847,0.02570305,-0.00523472,-0.018403322,-1.1348285329999999,-1.5131767459999999,-2.161050864,-2.0782511130000003,-2.523598587,-2.6975334330000003,2.098460884,0.747681459,-8.57026028,-7.59972274,-8.839180573,-7.886295692000001,-9.588770103,-8.937332291,-9.233522517,-8.524726012,-8.195291519165039,-10.039098739624023,-9.131034851074219,-9.694055557250977,-9.794679641723633 -640,640,S57R,-0.020317261,-0.026390838,-0.004827167,-3.63e-05,-0.129307108,0.064040284,-0.025159072,-0.015475448999999999,0.0040822490000000005,-0.014339355,-0.03844232,0.0010393919999999999,-0.010693726,0.017067651,-0.017140261,-0.12132630800000001,-0.137287907,1.341335418,2.224991218,-4.712526955,-3.7634872280000002,-4.760721443,-4.514400291,-5.750427795,-4.773598015,-4.84238626,-1.94624208,-6.022585868835449,-6.153293609619141,-5.234698295593262,-5.897114276885986,-4.629501819610596 -641,641,S57T,0.005376946999999999,-0.018162997,0.003326203,-0.001019837,-0.065115516,0.024178547999999998,0.009672883,0.001081011,0.048341563,-0.030015497000000002,-0.006310496,0.023308462000000002,-0.016656056000000002,-0.052996614000000004,0.05095694,-0.10799016300000001,-0.022240869,1.4069967719999998,2.2977707919999997,-2.320858521,-1.8043583369999998,-3.126137726,-1.5666153790000001,-2.378113152,-2.729068008,-2.541281294,-0.821961756,-5.0326995849609375,-5.0758056640625,-5.255826473236084,-5.857063293457031,-4.440997123718262 -642,642,S57W,-0.035707871,0.010650808999999999,0.014304718000000001,-0.007609767,-0.495673855,-0.07535813599999999,-0.065090821,-0.006324921,0.03362802,0.024866068999999998,-0.0035644509999999997,0.031550084,-0.0029406479999999997,-0.0027950609999999997,-0.012424471999999999,-0.38251440700000006,-0.6088333029999999,0.8035321670000001,1.532618686,-8.917248959,-6.810054909,-9.489147163,-8.50209655,-10.20008459,-9.58486158,-8.325882829,-6.236506034,-7.789295196533203,-9.697663307189941,-9.702205657958984,-9.25514030456543,-7.843818664550781 -643,643,S57V,-0.052295892999999996,-0.013614678,0.0218317,0.016770773,-0.09729119,0.07702263599999999,0.012746252,-0.117338038,0.07914694,-0.034573968,0.007344613000000001,0.026772543,0.016890857,0.010089846,0.0234517,-0.12074590699999999,-0.073836472,1.353746715,2.270184497,-5.244703833,-3.643005608,-6.570448586,-4.323586739,-5.831363372999999,-5.855114861000001,-5.231396782,-2.1116017769999997,-6.669785022735596,-7.127811431884766,-7.490654468536377,-7.503061294555664,-6.526827812194824 -644,644,S57Y,-0.004951861,-0.002948246,-0.03655248,-0.02762638,-0.39567102299999996,0.002009097,-0.010081703000000001,0.000177981,0.020931024,-0.015919478,0.010022986999999999,-0.013956151000000002,-0.059148808,-0.046205009000000005,-0.009047751,-0.30132717800000003,-0.490014867,1.4649955959999998,2.025613534,-6.054247644,-3.4174666819999997,-6.3552256620000005,-5.651023262000001,-7.430377235,-7.417145378,-6.279595541,-2.683717596,-6.866490364074707,-6.438027381896973,-7.97075080871582,-7.596809387207031,-6.538593292236328 -645,645,F58A,0.053703426,0.023405916000000002,0.0063174830000000005,0.043638360999999994,-0.096847901,0.037978173,0.035870629,0.071536222,-0.214490491,0.000774834,0.046036997999999996,0.005406816,0.00722815,-0.012274535,0.09955125699999999,-0.10341619099999999,-0.09027961,1.436732134,2.375580792,-3.6013236739999996,-4.760767685,-2.172290977,-4.741536133,-1.095916397,-5.236107178,-3.4126748999999994,-1.859468689,-3.7051305770874023,-5.456707000732422,-5.120706558227539,-5.613717079162598,-4.521003723144531 -646,646,F58C,0.075695117,0.1183562,0.025289073,0.096241539,-1.092346968,0.068389652,0.12328048400000001,0.028109749,-0.164393843,0.049370243,0.18734215699999998,0.027868082000000002,0.022710064,0.075846578,0.116636499,-1.2142463079999999,-0.970447628,0.5667302820000001,1.327073725,-4.0265188830000005,-4.7088513789999995,-2.9057226789999997,-3.825254005,-3.605151947,-5.087614403,-4.011841565,-3.7774965110000003,-4.26262092590332,-6.1775383949279785,-5.892060279846191,-7.355691909790039,-5.352749824523926 -647,647,F58E,0.031287255,0.03264178,-0.028907431,-0.660428802,-1.961057663,0.05576786,0.044749375,0.017825135,-0.144790998,-0.01923441,0.084517969,-0.055454698,-0.002360164,-0.35536655100000003,-0.9654910529999999,-1.946421665,-1.975693661,1.4962162030000001,1.361844319,-3.368897084,-3.902692886,-1.572657204,-5.056076889,-2.169550552,-4.1435078889999994,-3.204229822,-2.473618145,-4.836429595947266,-5.665404319763184,-6.167401313781738,-7.539728164672852,-5.622575759887695 -648,648,F58D,0.05737005,0.11386344300000001,-1.054667056,-1.816713315,-2.678411367,0.088615985,0.122826564,-0.008086464,-0.1467305,0.093683708,0.13404317699999999,-0.829809572,-1.27952454,-1.7902437569999998,-1.8431828719999999,-2.759267799,-2.597554935,2.1631619840000003,0.994874422,-4.8774362060000005,-6.1214145360000005,-2.91999427,-5.286204163,-3.901864677,-6.1577033839999995,-4.183316898,-3.227637785,-4.891646385192871,-4.68861198425293,-5.889895439147949,-7.745044708251953,-5.236029624938965 -649,649,F58G,0.042318228,0.069921796,0.023864113,-1.0700427240000001,-2.34256389,0.055180123,0.054546448,0.030090007000000002,-0.194720119,0.019081443,0.12076214800000001,0.00796039,0.039767835,-0.600708877,-1.53937657,-2.1106877269999997,-2.574440053,1.6852524830000002,1.345426249,-5.984155087,-6.581969765,-3.553832542,-6.9792631,-4.7704098660000005,-8.035300162999999,-5.678218104,-5.147866598999999,-4.715924263000488,-4.975447654724121,-5.664839744567871,-6.6662468910217285,-4.811273097991943 -650,650,F58I,0.065054418,0.071619853,0.037203604,0.04339302,-1.14552304,0.035935407,0.038936587,0.09117224800000001,-0.294190571,-0.015772413,0.159012119,-0.025114179,0.09952138699999999,0.036338037000000004,0.050448002,-0.9971439940000001,-1.293902086,0.716145415,1.3568031459999998,-2.464877974,-2.675883888,-4.2794480969999995,-2.5771159669999997,-2.23680085,-0.555141068,-3.00572788,0.999320566,-3.802668571472168,-4.988113880157471,-4.963820457458496,-6.012229919433594,-5.4658918380737305 -651,651,F58H,0.086669164,-0.000310913,-0.047290162999999996,0.025494098,0.026093905,0.039187741,0.083113652,0.09022467599999999,-0.178163608,-0.10276575800000001,0.10214393199999999,-0.123287425,0.028707099,-0.09938977,0.150377965,-0.066018359,0.118206169,1.3823330440000001,2.369509033,1.241556398,1.279864029,2.7687402189999997,1.369929222,1.156203423,-0.36695490299999994,-0.7702133259999999,1.103905254,-0.852959156036377,-1.509835958480835,-1.651888370513916,-3.671368360519409,-1.721766471862793 -652,652,F58K,0.057462835,0.11377443,0.059767707,0.121973303,-1.6374602880000002,0.055411401,0.08468631300000001,0.030239357,-0.268232033,0.082479151,0.145069709,0.077728852,0.041806561,0.113479114,0.130467491,-1.498997603,-1.7759229730000001,0.580756037,1.314514043,-2.973144965,-3.316693634,-0.12025032,-5.144599617,-3.1194090039999995,-3.1647722469999997,-3.782699628,-1.960582425,-4.55611515045166,-6.855154514312744,-6.018368721008301,-6.640468120574951,-4.669461727142334 -653,653,F58M,0.042891017000000004,0.064612983,-0.002764882,0.071615347,-0.179274328,-0.0055063840000000005,0.022457313,0.06332472,-0.26702333300000003,0.07208642900000001,0.057139536,0.008651723,-0.014181486,0.056058984000000006,0.08717171,-0.167584979,-0.19096367600000003,1.2152938,2.077279764,-3.6472431380000003,-3.7751538769999997,-4.139557571,-3.329104355,-3.3475749589999997,-3.6448249280000002,-3.309712984,-1.89479711,-4.390523910522461,-6.511436462402344,-5.553445816040039,-6.201066493988037,-6.349277496337891 -654,654,F58L,0.038395635,0.058953150999999995,0.018928703999999998,0.091389396,-0.46302966799999995,0.039074454,0.045157203,0.031634066,-0.150842194,0.014960128,0.102946174,0.05631289900000001,-0.018455491,0.078681844,0.10409694800000001,-0.289322433,-0.636736902,0.629248339,1.523176922,-2.291952379,-2.358106621,-3.015200539,-1.3157820279999999,-2.5256450040000002,-2.245027702,-2.6380409730000003,0.372004069,-2.845963478088379,-4.697075843811035,-3.923250913619995,-3.903109073638916,-4.530428886413574 -655,655,F58N,0.06750790599999999,0.071273244,0.036423784,0.119450076,0.020832937,0.004742411,0.044497905,0.090517906,-0.16243723,0.056974479,0.085572008,0.005013556,0.067834011,0.06381390299999999,0.17508624899999997,0.050482438,-0.008816565,1.1517464929999999,2.8489480910000005,-1.839786748,-2.3987015,0.309981918,-2.393475304,-2.0218022159999998,-2.694936638,-1.9959373809999998,-2.175855606,-3.2482352256774902,-3.86378812789917,-4.600878715515137,-6.498116493225098,-3.4678993225097656 -656,656,F58Q,0.02762736,0.052770797,0.010679443,0.042182075,-0.396714012,0.030971119,0.03494434,0.020310379,-0.21388601699999998,-0.005603581999999999,0.111145176,0.005901285,0.015457601000000001,0.009050524,0.075313625,-0.2698851,-0.5235429229999999,1.5405768690000001,2.131264544,-1.839245314,-1.20944281,-0.144272171,-2.635814644,-1.509096504,-3.697600441,-1.941657243,-1.820499462,-3.1377053260803223,-4.2342119216918945,-4.629328727722168,-5.48769474029541,-4.082916259765625 -657,657,F58P,0.025621697000000002,-1.655874927,-2.136885028,-2.19248557,-2.953853896,0.078188883,0.053294155,-0.002050761,-0.30651538300000003,-1.794212229,-1.517537624,-2.221950925,-2.05181913,-2.210098098,-2.174873041,-2.8603633760000005,-3.047344416,0.139921894,-1.2160799740000001,-6.839248616,-7.076975432999999,-5.561164597,-7.385935989,-5.734165955,-8.438001106,-6.528542936,-6.7661445879999995,-8.747570991516113,-10.195087432861328,-6.872096061706543,-9.549898147583008,-8.674507141113281 -658,658,F58S,0.030074318,0.042791256,-0.009680112,0.075776546,-0.12386197300000001,0.014903401,0.025583561,0.034565075,-0.19837834,0.009620063,0.075962448,-0.00177636,-0.017583863999999998,0.043656729000000005,0.107896362,-0.092954131,-0.154769815,1.290096231,2.319377947,-2.401836443,-3.9146939769999998,-0.335484695,-3.1783417430000003,-1.068517494,-3.512144302,-2.760671447,-1.880404534,-3.8361763954162598,-3.9803175926208496,-4.499997138977051,-6.104241847991943,-3.9936108589172363 -659,659,F58R,0.021534511,0.035974862999999996,0.005343663,0.063960018,-0.371947743,0.031782736,0.023285645,0.019783376000000002,-0.19464223100000003,0.027035007000000003,0.044914719000000006,0.022990762999999997,-0.012303437,0.059738770999999996,0.068181265,-0.26909844,-0.474797046,1.538419356,2.091996821,-1.855895274,-1.2799820179999999,-0.815947968,-1.655229279,-2.0418289869999997,-3.4864881210000003,-1.7465253109999999,-0.7896788379999999,-3.144197940826416,-5.148033142089844,-4.647403717041016,-4.076535224914551,-3.388794183731079 -660,660,F58T,0.016727221,0.032433079,-0.049513800000000004,0.060836745,-1.4008211919999998,0.05151606,0.017421324,0.016033117,-0.17345650199999998,-0.020093991999999998,0.084960149,-0.035475117,-0.06355248299999999,0.012890631000000001,0.10878285900000001,-1.127951885,-1.673690498,0.6546796779999999,1.339868359,-3.58893017,-3.8008980639999996,-2.491179779,-4.2855116419999995,-2.258207703,-5.108853661,-3.337422292,-2.518604133,-4.585380554199219,-6.229742527008057,-4.883667945861816,-7.602755546569824,-5.368849754333496 -661,661,F58W,0.097898921,0.073112629,0.051253868,0.090480436,0.038062554,0.044609526,0.10926005800000001,0.08653778300000001,-0.23036857800000002,0.026480551,0.11974470599999999,0.041909859,0.060597877,0.064960586,0.116000286,0.038220252,0.037904856,1.226956051,2.8425728360000004,0.165649355,-0.6207332,1.7372446819999998,0.123624969,0.25748485600000004,-0.669374535,-0.419325534,-0.09920534,-3.4329514503479004,-2.0882859230041504,-2.0019285678863525,-4.042967796325684,-3.8490166664123535 -662,662,F58V,0.028692807,0.074743462,0.040002758,0.113965939,-0.33502622,0.049219720999999994,0.022135064,0.035250549,-0.210415734,0.06868779700000001,0.080799126,0.08699119300000001,-0.006985676999999999,0.125852455,0.102079423,-0.208481253,-0.46157118700000005,1.2415502,2.0106484769999997,-2.256215257,-2.131777954,-3.728735435,-2.3018727340000003,-1.128338425,-1.9903517380000002,-2.05145733,0.6078729270000001,-3.5388684272766113,-5.844033718109131,-4.895603179931641,-6.207365989685059,-5.491670608520508 -663,663,F58Y,-0.022005373999999998,-0.004815293,-0.027550576,0.088073872,-0.020413011000000002,0.106657252,-0.003327738,-0.04068301,-0.165576783,-0.09519972800000001,0.08556914199999999,0.006941694,-0.062042846,0.025818304,0.15032944,-0.073284113,0.032458091,1.2199872859999998,2.328097342,2.810577368,1.907713646,3.8485631710000003,3.1970737610000004,2.733170494,2.366365768,1.631268395,1.278645988,-1.8150213956832886,-2.5842490196228027,-1.060755729675293,-2.8517279624938965,-2.361766815185547 -664,664,R59A,-0.042590036,-0.009806075,-0.014219912,-0.299772351,-1.9451652730000002,0.02673729,-0.009590043000000001,-0.075590029,-0.053517282,0.029697942,-0.04931009099999999,-0.001746285,-0.026693538,-0.136592425,-0.462952277,-1.7045823619999998,-2.185748184,1.099183575,1.3462331230000002,-7.037316512,-6.472022644,-7.287424758999999,-7.158469475,-6.188660515,-8.080005165,-5.888180525,-3.1289143439999996,-6.983732223510742,-9.418550491333008,-7.442385196685791,-9.25255012512207,-11.191299438476562 -665,665,R59C,-0.024958553999999997,0.004552714,-0.031984195,-1.026452236,-1.573662471,0.036745006000000004,0.031450621,-0.081367729,-0.029718634,-0.015187495,0.024292922,-0.024518187,-0.039450202000000004,-0.9129163779999999,-1.139988094,-1.409979551,-1.73734539,3.225896783,2.657104414,-10.57249205,-9.747202705,-10.35273053,-11.24563578,-10.0832047,-11.43368652,-8.717475851,-6.657244455,-8.826841354370117,-9.973777770996094,-8.83232307434082,-11.721891403198242,-10.24450397491455 -666,666,R59E,-0.061230755,0.070267371,-0.714981819,-1.75309971,-2.998283498,0.021716548999999998,-0.04198176,-0.080479749,-0.04908726099999999,0.041814639,0.098720103,-0.47639455399999997,-0.953569083,-1.566438108,-1.939761311,-2.594980198,-3.4015867969999998,1.7822807719999998,0.914195358,-7.942248407,-7.840119385,-7.893029816,-8.707571236,-6.562027802,-8.708493797000001,-6.546616016000001,-3.047025845,-7.616329669952393,-11.680296897888184,-9.702791213989258,-11.86568832397461,-13.067501068115234 -667,667,R59D,-0.065755847,-0.022956355,-1.238107865,-1.901520979,-3.24264753,0.074673979,-0.007084544,-0.124427149,0.054712038,-0.011067118,-0.034845591,-0.9858721840000001,-1.490343545,-1.754935515,-2.048106443,-2.850424395,-3.634870665,2.38602495,1.117118587,-6.95260229,-6.777798676000001,-7.395041908,-7.378039436,-6.181769492999999,-7.0303619379999995,-5.667329775,-1.8973460819999999,-6.53519868850708,-11.072856903076172,-8.843880653381348,-12.018889427185059,-12.348089218139648 -668,668,R59G,-0.100110431,0.001586835,0.0054936590000000006,-1.3972910369999998,-2.30278815,0.045180952999999996,-0.068039856,-0.132181005,-0.016586963,0.06292102299999999,-0.059747352999999996,0.033749461,-0.022762143,-1.102850864,-1.691731209,-2.388957256,-2.216619043,0.8084454179999999,0.752590434,-6.733596417,-5.96677668,-6.864717995,-6.253848686,-6.3564118579999995,-8.226226868,-6.005111808,-1.951926051,-9.21773624420166,-10.26407241821289,-8.787506103515625,-9.042520523071289,-11.19894027709961 -669,669,R59F,0.02912799,0.131202627,-0.8770012220000001,-1.75491193,-2.7694322239999996,-0.048511577,0.08382446,-0.025568481,0.011266968,0.146474049,0.11593120400000001,-0.560760894,-1.19324155,-1.486947645,-2.022876214,-2.339398476,-3.199465972,2.434101652,1.396393503,-11.94856035,-10.47429941,-10.67109741,-12.26678889,-11.40719805,-14.92341799,-8.32591348,-5.80072921,-8.942397117614746,-10.215895652770996,-10.57349967956543,-12.201289176940918,-13.546100616455078 -670,670,R59I,-0.045435409,-0.37814077799999996,-2.26922529,-2.365565035,-2.656506313,0.013935291,0.015190273999999998,-0.106061092,-0.078521358,-0.23978724399999998,-0.5164943120000001,-1.944668281,-2.5937822980000003,-1.967765046,-2.7633650239999996,-2.218155885,-3.094856741,1.01928359,-0.083652297,-10.28759677,-10.10684538,-9.050570412,-10.64357145,-9.603315506,-12.03368109,-8.113570381,-5.564838883999999,-8.734804153442383,-12.408096313476562,-10.882050514221191,-13.429637908935547,-13.507253646850586 -671,671,R59H,-0.090263181,0.027011045,0.028195907000000003,0.022095261,-0.328139955,-0.003005839,-0.08196505700000001,-0.098561305,-0.039351316000000004,0.10062112,-0.04659903,0.042703646,0.013688167,0.08930238,-0.045111859000000004,-0.248847958,-0.40743195200000004,1.097282766,1.830180642,-3.829263004,-3.41548143,-4.5174290919999995,-4.639884819,-3.2402657930000003,-3.3332538830000003,-4.469526615,-2.18938999,-6.111138343811035,-6.205657958984375,-6.901753902435303,-7.472461700439453,-9.526861190795898 -672,672,R59K,-0.03219834,0.028808057,-0.0007198080000000001,0.013379948000000001,-0.386167521,0.044967387000000004,-0.040613244,-0.023783435,-0.028311875,0.06301945,-0.005403336,0.009656943000000001,-0.011096558999999999,0.081187001,-0.054427105999999996,-0.19898022899999998,-0.573354812,1.360713075,2.097047964,-4.541923332,-4.230873222,-5.203248756,-5.256186478,-3.178509247,-4.840798958,-4.122695745,-3.4344966360000004,-5.951432228088379,-7.403444290161133,-6.886914253234863,-7.016853332519531,-9.705970764160156 -673,673,R59M,-0.071399525,0.012237583,0.022352959,-1.47320788,-2.432379025,0.009369572,-0.054696873,-0.08810217699999999,-0.108116188,0.041169225,-0.016694059,0.048996508,-0.00429059,-1.136915104,-1.809500655,-2.4015463830000003,-2.463211667,0.841818673,0.751361793,-9.642452947999999,-9.49129718,-8.509604942000001,-10.53417606,-9.157949477999999,-10.51923708,-7.729045212000001,-5.192755711,-8.337459564208984,-10.490286827087402,-10.169386863708496,-11.765358924865723,-12.783979415893555 -674,674,R59L,-0.09395732300000001,0.006592326,-0.192024289,-1.6761025090000001,-2.4079076280000002,0.031967654,-0.062492400999999996,-0.12542224400000002,-0.02004301,0.022748811,-0.00956416,-0.17076143100000002,-0.21328714699999998,-1.3554799480000002,-1.99672507,-2.2975415530000003,-2.518273703,0.945328032,0.7418052890000001,-8.117409747,-8.131699005,-6.509463226,-8.877495003,-7.523837547,-9.544553955,-6.735077498,-3.156569152,-6.3274664878845215,-9.300508499145508,-7.883814334869385,-9.968954086303711,-10.539634704589844 -675,675,R59N,-0.056316372999999996,-0.038195076,-0.059163611,0.014539776,-0.080553187,-0.136352127,-0.10283390699999999,-0.009798838,0.047171195,0.024503367,-0.100893518,-0.013119338000000001,-0.105207884,0.077382708,-0.048303157,-0.035332573,-0.12577380000000002,1.32522348,2.628793189,-3.864551964,-3.103199608,-4.401668861,-4.962664589,-3.575161964,-3.2800647960000004,-4.054445912,-0.211320111,-4.048065185546875,-5.983364105224609,-5.554934024810791,-8.646825790405273,-10.572195053100586 -676,676,R59Q,-0.047080892,0.023520317000000002,-0.039072019,-0.020442319,-1.436483915,-0.00298896,-0.040496735,-0.053665048,-0.051685895999999995,0.081803611,-0.034762978,0.025393113999999998,-0.103537152,0.068204406,-0.10908904400000001,-1.519645695,-1.3533221340000001,0.49850068299999994,1.308308003,-4.071791742,-3.662816978,-4.064066841,-5.050715446,-3.630952034,-3.95040741,-4.851268627,-2.4783538309999997,-5.905333518981934,-7.646090984344482,-6.84417200088501,-8.119624137878418,-9.181593894958496 -677,677,R59P,-0.061596319000000004,-1.3951278059999999,-1.9419356540000001,-2.091503064,-2.681074897,0.041340867999999996,-0.009504704000000001,-0.113687933,-0.045990764,-1.4736339980000002,-1.316621614,-1.827511065,-2.056360242,-1.850607829,-2.332398299,-2.2880853119999998,-3.074064481,4.010222422,1.7477097519999998,-11.27909548,-11.28242883,-10.96008427,-11.27062286,-10.4635381,-12.41880336,-9.645061972,-7.829719483,-11.609416961669922,-12.645284652709961,-11.522483825683594,-14.141124725341797,-14.986701965332031 -678,678,R59S,-0.054163725999999995,0.045891017,0.00872414,-0.861572468,-1.875296865,0.055914519,0.005905606999999999,-0.11423305800000001,0.0011172810000000001,0.062126962,0.029655072,0.011229832,0.006218446999999999,-0.427616499,-1.295528437,-1.67945258,-2.0711411490000002,1.6830140040000001,1.4625626090000001,-7.7802523710000004,-6.933135742,-7.733169357,-8.083130119,-7.159741951,-8.992084686,-6.585104841000001,-3.62608655,-7.697791576385498,-10.315947532653809,-8.382766723632812,-9.866968154907227,-11.189281463623047 -679,679,R59T,-0.072327592,0.01533939,-1.003471343,-1.726944719,-2.823482028,0.040687882,-0.035459925,-0.109195259,0.028848927000000003,0.045815144,-0.015136364,-0.73525841,-1.271684275,-1.528819596,-1.925069841,-2.455904046,-3.1910600089999996,2.4461285669999997,1.32204429,-9.443088037,-8.619338348,-9.50073307,-9.583378754,-8.829517807,-10.68247221,-7.722745159,-5.238081264,-8.42159652709961,-12.135684967041016,-10.201252937316895,-12.102320671081543,-12.852763175964355 -680,680,R59W,-0.085113947,0.040481937,-0.018723159,-1.5814416359999999,-2.399050209,0.025024459,-0.039688396,-0.130539497,-0.018110882,0.047032952999999995,0.03393092,0.021516305,-0.058962623,-1.208518716,-1.954364555,-2.185908284,-2.6121921340000003,0.99703554,0.7489775679999999,-11.38903369,-10.98464271,-10.29495852,-11.90124191,-11.53694681,-12.22737849,-10.12454405,-9.510327637,-10.209714889526367,-10.675065994262695,-11.646760940551758,-12.404006004333496,-11.390140533447266 -681,681,R59V,-0.069056612,-0.188942887,-1.504193137,-2.21401196,-3.269411588,0.045472478,-0.034711105,-0.103402119,-0.023226306000000002,-0.075407186,-0.30247858699999997,-1.430694301,-1.5776919719999998,-1.816968968,-2.611054951,-2.482333156,-4.05649002,3.066680349,1.51886324,-9.619794949,-9.611879555,-8.808767952,-9.909516258,-9.243965263,-10.52484572,-7.807601627,-5.104722384,-8.408088684082031,-12.1888427734375,-10.500457763671875,-12.88131332397461,-13.424715042114258 -682,682,R59Y,0.0052673780000000005,0.07103983700000001,0.029843654,-1.2148503309999998,-2.747228401,0.041797537,0.073808992,-0.063274236,-0.085264244,0.135032701,0.007046973000000001,0.03236036,0.027326947999999997,-0.8157865240000001,-1.6139141369999999,-2.344930965,-3.1495258369999997,1.778872614,1.2822968240000001,-10.03936373,-8.617595482,-10.6292198,-10.61092747,-9.522049583,-10.81702634,-7.641100389,-4.221834521,-8.1509370803833,-8.959351539611816,-9.064903259277344,-12.02014446258545,-12.226890563964844 -683,683,P60A,-0.04836535,-0.004979135,-0.000603067,0.007613094,-0.0036904209999999997,0.041708014,-0.065009165,-0.031721533999999996,-0.017038232,0.011214907,-0.021173176000000002,0.010812166000000002,-0.012018299999999999,0.035312657000000004,-0.020086469,0.071862168,-0.07924301,1.030512501,2.682596954,1.7897401730000002,1.369526855,2.176213158,1.716294601,1.709180725,1.9774855269999998,-1.009612059,1.637411201,-3.2030868530273438,-3.2255735397338867,-3.220837354660034,-1.2489633560180664,-3.1865241527557373 -684,684,P60C,-0.034201341,0.038522013,0.0033332690000000002,0.0216651,-1.87440672,-0.00835588,-0.044536717999999996,-0.023865962999999997,-0.037053368999999996,0.011214907,0.065829119,-0.008395946999999999,0.015062485,0.070314606,-0.026984406000000002,-1.344410815,-2.4044026240000003,0.569084163,1.321609415,-4.29919409,-4.156973853999999,-4.128149956000001,-3.885563873,-4.888862717,-4.436420052,-5.30835441,-3.504702734,-9.203689575195312,-8.432926177978516,-8.031147956848145,-7.057093143463135,-8.410543441772461 -685,685,P60E,0.015935289,0.039689396,-0.034909809,0.012443623999999999,0.019215496999999998,0.036139465,-0.016134585,0.048005163,-0.042570246,-0.01863624,0.09801503199999999,-0.08859954699999999,0.018779929,-0.055802678,0.080689926,-0.023370067999999997,0.061801062000000004,1.4671573,2.665763981,-0.27182323199999997,-0.21159453600000003,-0.165288101,-0.846256012,-0.613860611,0.477883102,-2.000330576,0.38758817100000004,-4.5425496101379395,-6.236008167266846,-4.258946895599365,-3.7607316970825195,-4.897019386291504 -686,686,P60D,-0.014733166,0.021542427000000003,0.031799341,0.029683141,0.010643743,0.003779805,-0.041429846,0.011963514,0.005622136,-0.009202998,0.052287850999999996,0.058786125,0.004812557,0.037711286000000004,0.021654995,0.07983167,-0.058544185,1.126870742,2.84560063,-2.587293001,-3.1004631810000003,-3.72216806,-1.98108992,-2.378792389,-1.753951454,-2.795441515,-0.616524957,-5.474599361419678,-6.110220432281494,-4.661750793457031,-4.844878196716309,-6.095837593078613 -687,687,P60G,0.030995073999999997,0.013120405,-0.019277883,0.007261521,-0.021573991,0.006501684000000001,0.023868785,0.038121363,-0.012809228,-0.030938237,0.057179047000000004,-0.027083508,-0.011472257,0.01345049,0.001072552,0.026024807,-0.069172788,1.200850847,2.7073447880000003,-0.143434258,0.203509369,0.310370193,0.10096694199999999,-1.129022812,-0.20299498,-1.662660878,1.159768042,-4.470570087432861,-4.386941909790039,-3.827023506164551,-1.511235237121582,-3.584240436553955 -688,688,P60F,0.001822431,0.060632872000000004,0.007436027,0.037889361,-1.310573596,0.039709044,0.038301003,-0.034656141,-0.014069165,0.058447822,0.062817922,-0.019478157,0.03435021,0.118753159,-0.042974437000000004,-0.779224275,-1.841922916,0.571954305,1.3606633680000002,-5.310452931,-5.626729156000001,-5.701757072,-4.841486572,-5.538373901,-4.843917953,-6.062264824,-4.8686156689999995,-8.296745300292969,-7.006352424621582,-6.53364372253418,-7.812844276428223,-8.265918731689453 -689,689,P60I,-0.031402446,0.099016312,0.040388106,0.054243485999999994,-0.070069557,0.033991912,-0.056106086,-0.006698806,0.035502249,0.125177294,0.07285533,0.100981679,-0.020205467,0.137706597,-0.029219625,-0.001932919,-0.138206195,1.239676548,2.841142242,-3.382186952,-3.913380425,-3.049807556,-3.53350573,-3.864397743,-2.5498433080000003,-3.980877027,-2.7821310489999997,-6.961115837097168,-7.425212860107422,-5.547657489776611,-6.584738731384277,-7.410736083984375 -690,690,P60H,-0.016951481,0.018089997,-0.041510258,0.015211658000000001,-0.000633666,-0.011591336,-0.041118969,0.007216006999999999,0.031508895,0.042277665,-0.006097671,-0.040020199,-0.043000316,0.014797278,0.015626038000000002,0.054070314,-0.055337645,1.057823004,2.69928244,-3.6799621,-3.299964127,-4.751987274,-2.550566704,-3.643813324,-4.153479073,-4.607733465,-2.595425396,-7.392838001251221,-6.241996765136719,-5.147512912750244,-6.7067975997924805,-6.767416954040527 -691,691,P60K,-0.006089837,0.016451137,0.018501808999999998,0.008513421,-0.067379763,0.002635555,-0.009142359000000001,-0.003037314,-0.05100500400000001,0.000284639,0.032617634,0.002524404,0.034479214,-0.019979259,0.037006101,-0.053019656,-0.08173987,1.285926774,2.394443934,-2.9933146610000003,-2.206793167,-4.139293747,-2.646391197,-2.745931343,-3.228163849,-3.961418155,-2.587132114,-7.927258014678955,-7.288242816925049,-6.510207176208496,-5.619378566741943,-6.060671806335449 -692,692,P60M,-0.003974583,0.01357206,-0.002607613,0.009209514,0.028805142000000002,0.033636914,0.014758188,-0.022707353,0.020097745,0.039704421000000004,-0.012560301999999999,0.014417436,-0.019632661000000003,0.035982585,-0.017563557,0.058320891,-0.000710608,1.190057792,2.955570893,-2.478572084,-2.9121144560000003,-2.260661957,-2.873435738,-2.8518336410000003,-1.494814629,-3.199615463,-2.7724602000000003,-8.05513858795166,-7.44802713394165,-6.431882858276367,-6.708559513092041,-6.473726749420166 -693,693,P60L,-0.056402031,0.025734487,0.012765024,0.0322581,-0.201132372,0.048973072,-0.052737809000000004,-0.060066252,-0.010035957,0.035622489,0.015846485,0.041874241,-0.016344193,0.061359763,0.003156436,-0.11916473300000001,-0.28310001,1.7177603769999998,2.670996696,-2.1670432330000002,-3.16683934,-1.87036837,-2.27328727,-2.706175064,-0.81854612,-2.554108236,-1.914438436,-7.162924766540527,-7.156777381896973,-4.912060737609863,-6.690338134765625,-6.21326208114624 -694,694,P60N,-0.011285648999999998,0.072278646,0.007683625,0.038777988,-0.28354777600000003,0.091404771,0.020589591,-0.043160888,0.030951296,0.057381206,0.087176085,0.031959659,-0.016592409,0.031261979,0.046293996,-0.196629518,-0.370466033,1.25985554,1.996258778,-3.74771433,-3.5604195560000003,-5.002845993,-3.172810699,-3.1273969189999997,-3.87509848,-5.0994843119999995,-0.862201855,-7.299360275268555,-5.815638542175293,-5.231678485870361,-6.0392279624938965,-5.486812114715576 -695,695,P60Q,-0.008239493,0.033192221,-0.057621955,0.010573048,0.01093068,0.007899241999999999,-0.05663390099999999,0.040154916,-0.01544058,0.057152512,0.009231929,-0.08041295,-0.03483096,0.063178912,-0.042032815999999994,0.055105582,-0.033244222999999996,1.171090344,2.9423430969999997,-0.941399001,-0.594023674,-1.73176886,-0.8709704970000001,-1.6323050540000001,0.122073082,-2.177287562,-0.994877648,-6.3890180587768555,-5.766546726226807,-4.611339092254639,-5.1300835609436035,-5.190911293029785 -696,696,P60S,-0.009322236999999999,0.043124534000000006,-0.001805577,0.034161437,0.030974114,0.013435455,-0.015123231000000001,-0.003521242,0.004597453,0.036610737000000004,0.049638330999999994,0.005077444,-0.008688597,0.027970655,0.040352219,0.061101339000000005,0.0008468880000000001,1.110969013,2.691206778,0.5875362120000001,0.36953370700000004,0.097412651,1.482212204,0.19282962,0.7956928790000001,-0.794452721,-0.24295268,-4.697933673858643,-3.208376169204712,-4.29792594909668,-2.827760934829712,-3.897287607192993 -697,697,P60R,-0.004414994,0.043772202,0.019712723999999997,0.040300622,-0.032174445,0.045328600999999996,-0.014805849,0.005975861,-0.005643515,0.06111149,0.026432913,0.027684787000000002,0.01174066,0.067820087,0.012781157,0.004652069,-0.069000959,1.143965006,2.71127695,-2.827401413,-2.994508087,-3.1421442410000004,-1.9882882769999999,-2.88616021,-3.12590625,-4.152948941,-2.761088304,-8.057096481323242,-7.259944915771484,-6.241579055786133,-5.687979221343994,-6.133090972900391 -698,698,P60T,0.000818803,0.022614209,-0.009437638,0.02905448,-0.035869273,0.018944151,-0.015293381000000002,0.016930986000000002,0.004355085,0.011060752,0.034167666,-0.032543914,0.013668639,0.024179832000000002,0.033929127,-0.037107722999999995,-0.034630822,1.3748626480000001,2.5870370609999997,-2.3142956619999997,-2.8288690869999997,-2.322224701,-1.680622963,-3.088640419,-1.65112114,-3.883220073,-2.715107843,-6.116168022155762,-4.566909313201904,-4.809629917144775,-4.874688148498535,-4.770973205566406 -699,699,P60W,-0.059501254,0.015172076000000001,-0.030994183999999998,0.03910482,-1.297597785,0.036699766,-0.040822016,-0.07818049099999999,-0.032926462999999996,0.004245137,0.026099014,-0.006697164,-0.055291203,0.059817551,0.018392088,-1.043970493,-1.551225076,0.726531226,1.3549708319999998,-5.519948232000001,-5.533830574,-5.699464057999999,-4.882254105,-5.815959023,-5.668233398,-5.995415764,-4.868615731,-10.483642578125,-10.077317237854004,-7.805380344390869,-8.617969512939453,-9.243780136108398 -700,700,P60V,-0.046430782999999996,0.017781198999999998,-0.030849562,0.001336067,-0.08649214,0.067162908,-0.029458435,-0.063403131,0.0043034779999999995,0.068992335,-0.033429937,-0.037817517,-0.023881607000000003,0.014797278,-0.012125145,-0.061187929,-0.111796351,1.3562165330000002,2.503366217,-2.354817043,-3.09641169,-2.29846093,-2.43045639,-2.203055725,-1.745700478,-3.2488386960000004,-1.97232178,-6.170252799987793,-6.422496795654297,-5.061678886413574,-5.634857654571533,-6.391040802001953 -701,701,P60Y,-0.06306302700000001,-0.001563967,-0.017699366,-0.003928153,-0.8071938129999999,0.0076700169999999995,-0.078637273,-0.047488780999999994,0.036197531,-0.035695104,0.032567171,2.56e-05,-0.035424332,-0.0033362870000000003,-0.004520019,-0.5502463160000001,-1.064141309,0.896020182,1.48144071,-6.4184263989999994,-5.974140945,-7.307632401,-5.634822571,-6.374250725,-6.801285355,-6.515645319,-5.522262105,-8.8015718460083,-7.306878089904785,-6.502186298370361,-8.330671310424805,-8.78697681427002 -702,702,E61A,0.063557894,-0.018393502,0.018657924,0.037613292,-0.012261803,0.08635234900000001,0.044354946,0.082760841,0.0042783940000000005,-0.071001751,0.034214747000000004,0.000537546,0.036778302,0.001721021,0.073505563,-0.05330610400000001,0.028782499,1.3507893030000002,2.49975486,-2.155384154,-2.025552635,-1.828559715,-1.9452663419999998,-2.570736351,-2.406805725,-2.625736819,-1.130478774,-5.820392608642578,-6.047770977020264,-5.67656135559082,-4.2053422927856445,-5.129605770111084 -703,703,E61C,0.001840954,0.056106345,0.02455509,-0.020366857,-1.223368361,0.0943779,0.003284038,0.00039787,-0.009460814,0.055272389000000005,0.0569403,0.076871164,-0.027760984,-0.026528789,-0.014204925,-0.711768721,-1.734968,0.82049415,1.421275426,-5.447578735,-4.947538849,-5.048990402,-5.853816642999999,-5.672109261,-5.715438522,-6.429881345,-4.394549692,-10.061288833618164,-12.4916353225708,-10.6036958694458,-9.15823745727539,-10.223224639892578 -704,704,E61D,0.024411174,-0.022018895,0.016038806,0.01835173,0.017772369,0.040897143,-0.024871083999999998,0.073693432,-0.008597704,-0.009966595,-0.034071194,0.044393927,-0.012316315,-0.00871353,0.045416989000000005,0.007855136,0.027689601,1.1983062279999999,2.6400548880000003,1.6444491680000002,2.5599435269999997,1.586135246,1.9702316359999998,0.612622925,1.493312508,0.778377199,1.885214551,-1.9495965242385864,-2.699772834777832,-2.5284152030944824,-2.555724620819092,-2.596014976501465 -705,705,E61G,-0.013910738,-0.048552622000000004,-0.039335574,-0.005067915,0.008092791,0.079627469,-0.020897202,-0.006924273000000001,-0.047917821,-0.039719612,-0.057385631,-0.025087297,-0.053583850999999995,-0.015957771000000003,0.005821941,-0.010719298,0.02690488,1.291626607,2.628278631,-1.5524512769999999,-1.431258797,-1.409923874,-1.318636498,-1.676094376,-1.926342842,-2.551537615,-0.241011161,-5.051172256469727,-6.245041370391846,-5.716041088104248,-4.318155765533447,-4.592125415802002 -706,706,E61F,0.084022179,-0.00046674199999999997,-0.003419893,0.093356546,0.036097238999999996,0.00847417,0.072232424,0.095811934,-0.032435712,0.025197822,-0.026131305,0.06877301799999999,-0.07561280299999999,0.057440812,0.12927228,0.008939763,0.063254715,1.149911372,2.605954966,-5.242485426,-3.7952004169999998,-4.90162825,-6.0686110079999995,-5.493646407999999,-5.953341049,-5.650905524,-3.552738117,-7.221691131591797,-9.120091438293457,-8.3016357421875,-6.527216911315918,-8.009106636047363 -707,707,E61I,0.09931897199999999,-0.018766218,0.025746305,0.03817622,-0.16817094800000001,0.06833893,0.07645502400000001,0.12218292,-7.38e-05,-0.06563237400000001,0.028099938999999997,-0.051762008,0.10325461699999999,-0.00844311,0.08479555,-0.201510918,-0.13483097800000002,1.354111417,2.066307219,-6.0807211489999995,-5.451577277999999,-5.599807236,-6.590404045,-6.123397636,-6.638419548,-6.903640192,-5.039763884,-8.607991218566895,-9.509410858154297,-9.303735733032227,-7.645556449890137,-8.677918434143066 -708,708,E61H,0.011416504,-0.0074982469999999996,0.032310451000000004,0.034168159,0.018249952,-0.004774258,-0.049567524,0.07240053099999999,0.035408597,-0.014565388,-0.000431105,0.062676679,0.001944223,0.022458297999999998,0.045878019000000006,0.029438053999999998,0.007061849,1.201053283,2.641557674,-1.794834117,-1.553714561,-1.822637749,-1.8451697459999998,-2.016146286,-1.7365022430000001,-3.2183948210000004,-0.83107925,-4.49373722076416,-6.68073844909668,-5.525882720947266,-4.643252372741699,-4.837806224822998 -709,709,E61K,0.081382181,0.026833051,0.118560038,0.084336492,0.051632487000000005,0.171953313,0.039165221,0.12359914,-0.147276252,-0.024622475,0.078288577,0.09655611300000001,0.140563962,0.013166086,0.155506897,0.010235895,0.093029078,1.283217775,2.834887473,-1.7137483340000002,-1.4659589919999998,-1.551543823,-2.160256767,-1.858978653,-1.532003433,-3.653917828,-1.028792049,-6.637156009674072,-8.173646926879883,-6.986825942993164,-5.584716320037842,-6.013711929321289 -710,710,E61M,0.054394780999999996,0.033971043,0.056696705,0.078574935,0.04607429,0.06785062900000001,0.014282757,0.094506804,-0.039827427,0.0032028340000000003,0.064739252,0.06420862,0.04918478900000001,0.002073009,0.15507686,-0.012388618,0.10453719800000001,1.1360743309999999,2.469853608,-4.543099944,-4.168432411,-4.044610229,-5.436769531,-4.38429036,-4.681397186,-5.3317085539999995,-3.182739017,-7.652565002441406,-8.818942070007324,-8.058058738708496,-6.144622802734375,-7.875577926635742 -711,711,E61L,0.022090156,-0.047770883,-0.024585716,0.02011436,-0.043914108,0.011503476,-0.010121701,0.054302012999999996,-0.041403239,-0.054929402,-0.040612363,-0.014842443,-0.034328989,-0.011171658000000001,0.051400378,-0.064323226,-0.02350499,1.270198658,2.429479188,-4.368369296,-4.024441605,-3.8833066560000002,-5.070032166,-4.185668633,-4.678397423,-5.068428063,-2.932747478,-6.963172912597656,-7.941335201263428,-7.6006083488464355,-5.403254985809326,-6.856881141662598 -712,712,E61N,0.029927954,-0.014141241,0.011966718999999999,-0.011644096999999999,-0.016952500000000002,0.05637949,0.018082728,0.041773179,-0.03285874,-0.033313999999999996,0.005031518,0.035436877,-0.011503438999999999,-0.055003027,0.031714834,-0.055784202000000005,0.021879202,1.187372712,2.582314897,-0.082960959,0.444704124,0.044830710999999995,-0.588744865,-0.199732574,-0.11586219,-2.3808324130000003,0.264784808,-3.711988925933838,-5.026656150817871,-4.6210713386535645,-3.6166229248046875,-3.971818685531616 -713,713,E61Q,0.073308264,0.08216560099999999,0.050951592000000004,0.04309535,0.030477973,0.026678433999999997,0.005104982,0.141511545,-0.020087996,0.06995767,0.094373531,0.09752501599999999,0.0043781670000000005,-0.000484179,0.08667487900000001,0.07606690099999999,-0.015110955,1.0600670159999999,2.791847385,-1.3659188519999999,-1.696627426,-1.2735308909999998,-1.5178932569999999,-1.17379464,-1.1677480470000001,-2.771733215,-1.062769415,-5.021911144256592,-5.50098180770874,-4.904818534851074,-3.805893898010254,-4.319754123687744 -714,714,E61P,0.010494823,-0.9750788579999999,-1.892559423,-2.220149339,-2.8231702000000003,0.09721601,0.01114723,0.009842416,-0.030467012,-0.894647218,-1.055510497,-1.9706686690000002,-1.8144501769999999,-2.2099665490000002,-2.230332128,-2.731179734,-2.9151606660000002,1.824619222,-0.024242249,-5.4524351929999995,-4.917523911,-5.032420387,-5.772874954,-5.875061317,-5.664295395,-6.431826537,-4.26893643,-10.872998237609863,-11.119110107421875,-10.121895790100098,-9.843935012817383,-10.39315128326416 -715,715,E61S,0.059884694,-0.02494304,0.010314503000000001,0.035750894,0.012718307,0.07310902400000001,0.027170126,0.09259926199999999,-0.04275198,-0.041325152000000004,-0.008560927,-0.009342175,0.02997118,-0.0026621759999999996,0.074163964,-0.01445115,0.039887764,1.355524107,2.693486272,-1.84757691,-1.656852486,-1.44380172,-2.251457459,-2.1953826519999997,-1.690390236,-3.649193504,-0.722235318,-5.506262302398682,-6.215951919555664,-5.6304931640625,-4.403752326965332,-5.074385643005371 -716,716,E61R,0.012236341000000001,-0.031955027999999996,0.007580619,-0.000541371,-0.029997036,0.09699304,-0.020821655,0.045294336,-0.031057831,-0.036625469,-0.027284586,0.016303468999999998,-0.001142231,-0.027965607000000003,0.026882865,-0.034520376,-0.025473695,1.334904031,2.534968346,-2.389532899,-2.758966515,-2.327954803,-2.481797539,-2.427677086,-1.951268555,-4.654248852,-1.340625529,-7.42071008682251,-9.022201538085938,-7.88503885269165,-6.312669277191162,-6.6363043785095215 -717,717,E61T,0.042707500999999995,-0.040018981,0.03847835,0.016013805,-0.035050369,0.047572163,0.009279288,0.076135713,0.031730237,-0.04655978400000001,-0.033478177000000005,0.048763744000000005,0.028192955,0.006071656,0.025955952999999997,-0.008942462,-0.061158275,1.155729208,2.502711711,-1.965605602,-1.82394857,-1.711977783,-2.292309151,-2.480125191,-1.519667313,-3.488624273,-0.872233789,-5.212669372558594,-5.7968902587890625,-4.823763847351074,-3.634875535964966,-4.7801923751831055 -718,718,E61W,0.012509989,-0.093801157,-0.002535813,-0.017620335,-0.017401177,0.034984327999999995,-0.028692844,0.053712820999999994,-0.062628952,-0.084668849,-0.102933465,-0.013049321000000001,0.007977695,-0.015289883,-0.019950786,-0.054834184,0.020031831,1.4110892069999998,2.462063717,-6.967881641,-6.166737312,-6.3129172129999995,-7.617168861000001,-7.6423485410000005,-7.100236275,-7.806903161,-6.904467192,-9.021017074584961,-12.186505317687988,-9.992902755737305,-8.446171760559082,-9.170406341552734 -719,719,E61V,0.032545471,0.016172889,0.058994500000000005,0.044248441,-0.074498357,0.022989292999999997,0.010752814,0.054338128,-0.136064325,-0.014152066999999999,0.046497844,0.053363543,0.064625457,0.0018537229999999998,0.08664315800000001,-0.08880883,-0.060187884000000004,1.264080769,2.326350792,-5.634791203,-5.15283857,-5.264693123,-5.924326217999999,-5.959013023,-5.873085082999999,-6.150970889,-4.707986016,-7.775293827056885,-8.5855712890625,-8.159099578857422,-6.946290493011475,-7.861878395080566 -720,720,E61Y,0.027267022000000002,0.014843124,-0.027411743,0.044179771,0.021190484,0.043230267,-0.004781514000000001,0.059315558,-0.075663517,-0.015222871,0.044909119000000004,-0.025148255,-0.02967523,0.028056064,0.060303478,0.04400175,-0.001620782,1.1075755059999999,2.761382807,-4.332429865,-2.982725098,-4.339877983,-5.115777168,-4.452688866,-4.771080208,-5.041387493,-2.7347391410000004,-6.818919658660889,-9.035772323608398,-7.141253471374512,-6.474863529205322,-7.041071891784668 -721,721,E62A,0.057473014,-0.068437308,-0.022054587999999997,-0.058308636,-1.023939685,-0.037792471,0.069092883,0.045853144000000005,-0.157236776,-0.14233916,0.005464545,-0.071693893,0.027584717,-0.130848237,0.014230966000000001,-0.729163351,-1.318716018,1.9943146409999999,2.054932464,-3.999530995,-4.134581055,-4.044426689,-4.383674133,-3.695254097,-3.7397190019999997,-3.4371146130000003,-2.462619106,-9.586348533630371,-10.262804985046387,-9.271282196044922,-9.222734451293945,-10.293517112731934 -722,722,E62C,0.042274149000000004,-0.12143756900000001,-0.013264833,-0.086399352,-1.82322916,0.028063802000000002,0.12417614699999999,-0.03962785,-0.211192888,-0.19204332600000001,-0.050831812000000004,-0.058664733,0.032135067,-0.05605222,-0.11674648300000001,-1.6400533080000002,-2.006405012,0.8549783390000001,1.321813471,-8.316265564,-8.264859337,-7.479309586,-8.964481827,-7.815267036,-9.057410034,-6.925598376,-5.295657948000001,-13.98917007446289,-17.81456184387207,-12.234116554260254,-14.254096984863281,-15.527571678161621 -723,723,E62D,-0.0074037059999999995,-0.117832134,-0.024481753999999998,-0.052771188,-0.100650825,-0.007976516,0.026175254,-0.040982666,-0.18075276699999998,-0.20057545,-0.035088817,-0.062290609000000004,0.013327101000000001,-0.049543105,-0.05599927,-0.157552444,-0.043749205,1.486383896,2.224128984,-3.1662677410000004,-2.403731842,-2.341426514,-3.362663338,-3.27143309,-4.452083923,-3.358354545,-1.975962715,-7.176329612731934,-7.596325874328613,-7.269631862640381,-8.610575675964355,-8.060460090637207 -724,724,E62G,0.033345852,-0.045591752,0.012688699,-0.028065378999999998,-1.366168672,0.005711112,0.065714434,0.00097727,-0.162906779,-0.101420483,0.010236979,-0.005008394,0.030385792000000002,-0.029115452000000003,-0.027015305,-1.338544487,-1.393792856,0.773145656,1.337382617,-6.219946792999999,-6.2820165789999995,-5.3518001019999994,-6.742992516,-5.54053418,-7.182390587,-5.161135983,-3.732310641,-11.715150833129883,-11.651020050048828,-11.074572563171387,-10.532350540161133,-12.017313003540039 -725,725,E62F,0.062333305,-0.116990796,-0.082009373,-0.02231879,-1.220230028,-0.013219301000000001,0.08284925,0.041817359,-0.071007853,-0.257102409,0.023120817000000002,-0.16044077699999998,-0.003577968,-0.080991779,0.036354199,-1.26524793,-1.175212126,1.116169412,1.394104454,-9.539380431,-8.887344673,-7.651852402,-11.09285929,-9.257720345,-10.80712544,-6.561811819,-4.66466524,-11.369165420532227,-14.893061637878418,-11.108487129211426,-13.429229736328125,-13.217855453491211 -726,726,E62I,0.046353487,-0.055628559,-0.056898239,-0.04850649,-1.344574689,0.014523478000000001,0.086647876,0.006059098000000001,-0.17580372800000002,-0.141360965,0.030103847000000003,-0.007114375,-0.10668210199999999,-0.051669558,-0.045343422,-1.4081183069999998,-1.28103107,0.727198626,1.328669588,-7.938311865,-7.532942139,-6.996696227999999,-8.625377517999999,-7.641829132000001,-8.89471431,-6.2786027870000005,-3.8053244889999998,-11.890442848205566,-13.730561256408691,-10.978464126586914,-11.417755126953125,-12.889464378356934 -727,727,E62H,0.010724481999999999,-0.11928120800000001,-0.019642727,-0.090061275,-0.66028634,-0.014945307,0.039477632,-0.018028668,-0.15884294599999998,-0.14329443,-0.095267985,-0.074136261,0.034850807000000004,-0.10278144300000001,-0.07734110599999999,-0.541009166,-0.779563514,1.340589675,1.697964927,-6.519878671,-6.082076859,-5.366415161,-7.73332782,-6.16233194,-7.2552415770000005,-5.2951670669999995,-3.477391585,-9.849645614624023,-13.027541160583496,-10.177812576293945,-10.91663646697998,-11.21596908569336 -728,728,E62K,-0.028776684,-0.089657145,-0.057783907999999995,-0.129572348,-1.893940849,0.004829364,-0.017884629,-0.039668739,-0.274654342,-0.15449398,-0.024820309,-0.08460281,-0.030965005,-0.10374907,-0.155395625,-1.7894590540000002,-1.9984226440000001,0.843555078,1.313262086,-5.3598239119999995,-4.739071152,-4.511423386000001,-7.060913612,-4.718440773,-5.769270637999999,-4.580831733999999,-2.116349898,-11.24392318725586,-11.782000541687012,-10.303350448608398,-9.581310272216797,-10.923707008361816 -729,729,E62M,0.099765744,-0.035625317999999996,0.011909786,-0.032663627,-0.358510262,-0.05332559,0.108766772,0.090764716,-0.202313716,-0.100680206,0.029429571,-0.07809058,0.10191015099999999,-0.015816112,-0.049511140999999995,-0.350933536,-0.36608698799999995,1.447161352,1.93901136,-6.816425671,-6.09575074,-6.2482927020000005,-8.155899848999999,-6.676098251,-6.906086815,-5.314935974,-3.609943238,-10.874006271362305,-12.395883560180664,-10.170699119567871,-8.994559288024902,-12.581192016601562 -730,730,E62L,-0.006835099,-0.069357455,-0.053868757999999996,-0.062592013,-1.942943043,-0.003179359,0.020497501,-0.034167697999999996,-0.194971851,-0.108602054,-0.030112856,-0.081288762,-0.026448753999999998,-0.04000742,-0.085176605,-1.4758399309999999,-2.410046154,0.94388828,1.343679321,-6.984019052000001,-6.235318877999999,-6.272127257999999,-8.018081383,-6.8501548539999995,-7.544412887999999,-5.0867461689999995,-2.988049167,-9.932726860046387,-11.95347785949707,-9.31535816192627,-10.397987365722656,-11.919880867004395 -731,731,E62N,0.0032209229999999997,-0.072703974,-0.04316417400000001,-0.07238916,-1.491877677,0.0054445909999999995,-0.002186603,0.008628448,-0.095499586,-0.170502767,0.02509482,-0.087471995,0.001143648,-0.056698973,-0.088079346,-1.104165272,-1.8795900819999998,0.624383502,1.340195457,-6.212770065,-5.601658859,-5.467866455,-7.326501541,-5.756139107,-6.911684364,-5.756159806,-3.832298895,-11.014166831970215,-12.424354553222656,-10.670801162719727,-10.81815242767334,-12.00120735168457 -732,732,E62Q,0.061097446,-0.069194688,-0.007620568,-0.045751279000000006,-0.310831814,-0.087726809,0.050104307,0.072090584,-0.051009757999999995,-0.10445769199999999,-0.033931683,-0.086116235,0.070875099,-0.113353654,0.021851097000000003,-0.33497267,-0.286690958,1.771994887,2.2127113169999997,-2.953250681,-2.28539772,-2.777685242,-4.14643222,-2.495393387,-3.061344833,-2.943035715,-1.970683841,-8.839727401733398,-7.977898597717285,-7.3668928146362305,-7.373392581939697,-8.493160247802734 -733,733,E62P,-0.016243763,-1.479490774,-2.007118191,-2.3435573080000003,-2.7961000169999997,0.002751608,-0.000136789,-0.032350737000000004,-0.219519247,-1.665769511,-1.293212036,-2.1230137940000002,-1.8912225880000002,-2.2670523940000002,-2.420062221,-2.6953968839999995,-2.89680315,0.082204336,-1.116553491,-9.228824875,-9.313409308999999,-8.538037819,-9.673707855,-8.714990112,-9.903979279,-8.069129252,-6.519158986,-13.688953399658203,-15.998367309570312,-13.171229362487793,-13.356940269470215,-16.082027435302734 -734,734,E62S,0.012566713,-0.039193313,-0.005399597,-0.049149026,-0.991022422,-0.040509579,0.00982489,0.015308536000000001,-0.157198668,-0.067493949,-0.010892677,-0.050283172,0.039483977999999996,-0.060382625,-0.037915427,-0.670589813,-1.31145503,0.894347698,1.448742021,-4.583587503,-4.799233322,-4.467634033,-5.481898811000001,-3.932023071,-4.237148277,-4.777297667,-3.114443917,-11.169698715209961,-12.088800430297852,-10.07065486907959,-10.159754753112793,-11.686480522155762 -735,735,E62R,0.036320027000000005,-0.043425958,0.000866879,-0.070105213,-2.055450033,0.02293856,0.053948540999999996,0.018691513,-0.155366809,-0.12142668400000001,0.034574769,-0.066141495,0.067875252,-0.052963783,-0.087246642,-1.7066566459999999,-2.404243419,0.918369718,1.323135725,-4.6518779939999995,-3.88831498,-3.779259232,-5.8433144,-4.666684685,-5.0818166730000005,-4.171810855,-1.739471885,-11.957536697387695,-13.458285331726074,-10.444372177124023,-10.551521301269531,-11.823629379272461 -736,736,E62T,-0.012736448000000001,-0.087258738,-0.087441348,-0.084723466,-0.29157128600000004,-0.060228040999999996,-0.027513164,0.002040268,-0.176732663,-0.11171819,-0.062799286,-0.128939876,-0.04594282,-0.093840781,-0.075606151,-0.26823922,-0.31490335199999997,1.542292374,2.081401642,-4.581104628,-4.593128265,-4.220194962,-5.073418633,-4.212344231,-4.80643705,-5.1275822689999995,-2.045240493,-10.328459739685059,-11.552570343017578,-9.38674545288086,-9.237850189208984,-11.120258331298828 -737,737,E62W,0.086498837,-0.06090279,-0.038870471000000004,-0.012690395,-1.9314546240000001,-0.075435128,0.091618831,0.08137884299999999,-0.14861068800000002,-0.184164651,0.062359072,-0.12878382300000002,0.051042881,-0.046804825,0.021424036,-1.6645843390000001,-2.198324909,0.6878522159999999,1.31160748,-10.49994027,-9.773269691,-8.897498947,-11.927321300000001,-10.23526061,-11.66635082,-8.574534898,-7.384837031,-10.221531867980957,-16.329692840576172,-9.062963485717773,-14.028444290161133,-12.303306579589844 -738,738,E62V,-0.001870541,-0.121185084,-0.017289387,-0.043605708,-0.936311053,0.012342856000000001,0.023304282000000003,-0.027045363,-0.18686835,-0.164644898,-0.07772527,-0.06591284900000001,0.031334075,-0.028124287999999997,-0.059087127999999996,-0.6435998479999999,-1.2290222579999999,1.528433409,1.780285502,-6.587497131,-5.939729423999999,-5.596568085,-7.1417764429999995,-6.719195366,-7.540216339,-5.222336449,-2.5934347680000003,-10.77603530883789,-12.19475269317627,-9.740632057189941,-10.391474723815918,-11.552582740783691 -739,739,E62Y,-0.008455438000000001,-0.070276425,0.046305106,-0.059928347,-1.2178737,-0.003224918,-0.006609425,-0.01030145,-0.160316776,-0.12289499400000001,-0.017657855,-0.001258893,0.09386910400000001,-0.08396715,-0.035889542999999996,-0.965614335,-1.470133064,1.0466992929999999,1.428955096,-9.857638837,-9.821087486,-7.830883881,-11.13826691,-9.066796356000001,-11.43115955,-6.787782095,-4.94285288,-11.778480529785156,-14.226764678955078,-10.914054870605469,-13.168464660644531,-12.643697738647461 -740,740,R63A,-0.053937372000000004,0.02686806,-0.027505855,-0.027537789,-1.552993834,0.02522155,-0.034855687999999996,-0.073019055,-0.05945277,0.024921336000000002,0.028814784,-0.036995679,-0.018016031000000002,-0.011864608,-0.043210969,-1.204657826,-1.901329841,0.783630527,1.347390092,-6.139308664,-5.8964319000000005,-6.442352402,-6.174938599,-6.831125572,-5.351694847,-4.181020258999999,-2.463916723,-8.697063446044922,-6.770381450653076,-9.291110038757324,-10.51472282409668,-11.595787048339844 -741,741,R63C,0.0037786820000000002,0.052228344,0.039806486,-0.11080175800000001,-1.5772824909999998,0.012800858,0.0063996090000000005,0.001157754,0.061034622000000004,0.009931759,0.09452492900000001,0.048658555,0.030954417,-0.092447451,-0.12915606400000001,-1.581911065,-1.572653916,1.0241111840000001,1.343607555,-8.949303322,-9.903201141,-8.712929184,-8.521634322999999,-9.315056709,-8.293695251,-7.146964873,-5.792937447000001,-10.536752700805664,-8.858348846435547,-9.186325073242188,-11.033427238464355,-11.00777816772461 -742,742,R63E,-0.049669841,0.023391586000000002,-0.042143479000000005,-0.036506677,-1.482423194,0.025941044,-0.019756125,-0.079583556,0.02516146,0.003865467,0.042917705,-0.07774742,-0.006539538,0.00172408,-0.07473743299999999,-1.6450813569999998,-1.319765031,0.7323203859999999,1.316981787,-10.41243823,-12.67499421,-9.299268188,-10.58946328,-10.19460715,-9.303858307,-6.100753338,-2.8634247719999997,-13.24313735961914,-10.537511825561523,-12.285911560058594,-14.106588363647461,-13.800337791442871 -743,743,R63D,-0.093154388,0.00822422,-0.169084097,-1.836651517,-2.506009658,0.057251345999999995,-0.016668201,-0.169640574,-0.049309202,0.001611686,0.014836753999999999,-0.13328071800000002,-0.204887475,-1.497424246,-2.175878787,-2.2817575469999998,-2.7302617689999997,1.168358658,0.757981958,-11.29103313,-12.77301491,-12.5106276,-11.18095947,-9.7030355,-10.28752816,-7.3795049729999995,-4.374417863,-13.827916145324707,-11.220212936401367,-12.83839225769043,-15.302984237670898,-14.72188949584961 -744,744,R63G,-0.064787167,0.020064104,-0.015426586,-1.322110985,-2.512185941,0.005717024,-0.034450614,-0.09512372,-0.007465448,0.027696412000000004,0.012431796,-0.03010389,-0.0007492810000000001,-0.834621542,-1.809600427,-2.244839517,-2.7795323639999996,1.83777074,1.33816789,-9.22614644,-9.844372314,-8.594358459,-9.663007393,-9.636149811000001,-8.392844222999999,-6.518095446,-4.513749946,-11.547800064086914,-10.261899948120117,-11.253823280334473,-11.734244346618652,-11.66648006439209 -745,745,R63F,-0.069008369,0.029277964,-0.08650067199999999,-0.074559971,-1.8281826380000001,-0.061251133,-0.081522341,-0.056494395999999995,0.023797897000000002,-0.032071427,0.090627355,-0.04345605,-0.129545294,0.028628318,-0.177748259,-1.4123506730000002,-2.244014602,0.60156222,1.319371867,-8.530368129,-8.331327965,-8.043347099,-9.508874413,-9.067476822,-7.7008143460000005,-6.754426157999999,-4.699963656,-12.490479469299316,-10.39019775390625,-12.241378784179688,-12.248061180114746,-12.805989265441895 -746,746,R63I,-0.053876189000000005,-0.001550838,0.045928416,-0.065170486,-1.001374095,0.060208595,0.018931754,-0.126684131,-0.023974885,0.064929465,-0.06803114,0.075752914,0.016103917,0.030027553999999998,-0.160368525,-0.534333003,-1.4684151859999999,0.716476379,1.43715286,-9.291897765,-10.21273226,-9.04242157,-9.14089209,-8.187891953,-9.875550948999999,-6.595232809,-2.50538904,-9.713010787963867,-8.75757122039795,-10.68172550201416,-11.771183967590332,-12.334115028381348 -747,747,R63H,-0.063345388,-0.009265087,-0.031860967999999996,-0.054240048,-0.532573946,0.037572934,-0.030349152999999997,-0.09634162199999999,0.08146513799999999,0.005718604,-0.024248778,-0.031477879,-0.032244057,-0.035958123,-0.072521973,-0.421945722,-0.6432021689999999,1.4089443990000001,1.867423219,-5.947789211,-7.30736013,-5.5390885160000005,-5.753142616,-5.889709273999999,-5.249645515,-5.07289508,-2.5520022669999998,-10.20303726196289,-6.9875688552856445,-8.779937744140625,-8.98167610168457,-8.476166725158691 -748,748,R63K,-0.060374055999999995,0.035512884,-0.009030466,-0.038527773,-0.162804455,0.056068325999999995,-0.046524829000000004,-0.074223283,-0.032222669,0.046654565999999995,0.024371201000000002,0.013749305,-0.031810236,0.005073814,-0.08212936,-0.146046799,-0.17956211100000002,1.430093859,2.296490931,-7.332225139,-7.598518326000001,-6.723132065,-7.632073029,-7.302365341000001,-7.405036934,-5.874237096,-2.447747845,-8.913310050964355,-7.223654270172119,-9.072232246398926,-9.522812843322754,-9.11143684387207 -749,749,R63M,-0.051347407000000005,0.06806669900000001,-0.007027078000000001,-0.058392767000000005,-1.270809434,0.010663632,-0.057121157,-0.045573656,0.083235085,0.08385190099999999,0.052281496,-0.023821027,0.009766871,-0.008987105,-0.107798429,-1.144038186,-1.3975806819999999,0.688106978,1.341730603,-7.421247154,-8.512249268,-7.6127682420000005,-7.479885887000001,-7.442247237999999,-6.059085136,-6.2742560229999995,-4.082656486,-11.323277473449707,-9.820213317871094,-11.238332748413086,-11.520960807800293,-12.56764030456543 -750,750,R63L,0.011221663,0.038670758,-0.014093258000000001,-0.010820682,-0.418237842,-0.010758203999999999,0.005697707,0.016745619,0.024830702000000003,0.036347288,0.040994227,-0.022672988999999998,-0.0055135259999999995,0.009836859,-0.031478223,-0.306941532,-0.529534151,1.130292289,1.752828686,-4.497442244,-4.641254288,-4.218142548,-4.890832207,-5.012228592,-3.7247535860000003,-5.243967068,-1.942311951,-9.46069049835205,-7.603984832763672,-9.320384979248047,-9.570974349975586,-9.715599060058594 -751,751,R63N,-0.080355608,-0.017129643,0.040729468,0.05179803,-1.582375994,-0.07005795,-0.090942465,-0.06976875099999999,0.019867603,0.028224475,-0.06248376,0.049132589000000004,0.032326346,0.120724249,-0.017128189,-1.4123506730000002,-1.752401314,0.448112726,1.31190732,-10.24764977,-11.55348384,-9.331865898,-10.17172666,-10.03741586,-10.14375659,-7.327211148,-4.085044528,-11.556910514831543,-9.344425201416016,-10.932501792907715,-12.87619400024414,-11.593466758728027 -752,752,R63Q,-0.032623525,0.05981111,-0.050418462000000004,-0.015736444,-0.693159062,0.003327024,-0.025634574,-0.039612476,3.75e-05,0.07184611099999999,0.047776109000000004,0.015289467,-0.11612639,0.008694059,-0.040166946,-0.514601681,-0.871716443,0.8582965109999999,1.484045655,-7.800900121000001,-9.20846595,-7.387675354,-7.315996254,-7.508277206,-7.584085837999999,-5.791352037,-2.788628912,-10.028409957885742,-7.368670463562012,-9.014870643615723,-9.336254119873047,-9.855205535888672 -753,753,R63P,-0.028605882000000003,0.003872278,-0.016073859,-0.023242573,-1.086821958,-0.0027440340000000002,-0.018305773,-0.03890599,0.002451501,-0.008168219000000001,0.015912773999999998,-0.009977855,-0.022169862999999998,-0.013150964,-0.033334181000000004,-0.806714335,-1.36692958,0.80918625,1.395967489,-6.22511566,-6.010014694,-5.748600685,-6.272649055,-7.102545952000001,-5.9917679139999995,-5.600562557999999,-1.308622927,-9.123135566711426,-6.143161773681641,-8.672545433044434,-9.991303443908691,-9.370946884155273 -754,754,R63S,-0.06283103799999999,0.010383432,-0.032349657999999996,-0.053699102,-1.2961362029999999,0.021958796000000003,-0.056132727,-0.069529348,0.051454634000000006,0.012871823999999999,0.00789504,-0.041153503,-0.023545812000000003,-0.030677641000000002,-0.07672056299999999,-1.02094819,-1.571324216,0.992518998,1.399458909,-6.4089486529999995,-7.492794677999999,-6.446434525,-6.292117966,-6.166379302999999,-5.6470167920000005,-5.462545058,-2.421000261,-10.277257919311523,-7.220412254333496,-9.641201972961426,-10.6722993850708,-10.369832038879395 -755,755,R63T,0.002459675,0.059841810999999995,0.023692966,0.007443551,-0.626124444,0.000400691,0.019389115,-0.014469766,-0.015746644,0.06916190700000001,0.050521714,0.031447134,0.015938797,0.023284213999999998,-0.008397112,-0.46905748,-0.783191408,0.821384722,1.490724102,-6.676408226,-7.77584819,-6.719531998,-6.392919113,-7.045464691,-5.448277138,-5.122309315,-2.71962727,-11.43299674987793,-7.438899040222168,-9.788578033447266,-11.473042488098145,-11.754817008972168 -756,756,R63W,-0.07595975099999999,-0.03415708,0.008220798,-1.042068925,-2.318079555,-0.021050898999999998,-0.066800785,-0.085118717,0.097584111,-0.038597643,-0.029716517,-0.001299112,0.017740706999999998,-0.548690149,-1.5354477,-1.9265396680000002,-2.709619441,1.778474736,1.413689428,-9.062352611,-9.407581352000001,-8.898942513,-9.466279839,-9.502400795,-8.036558556000001,-7.738876758,-5.288188634,-11.527533531188965,-11.590309143066406,-12.8474702835083,-12.759183883666992,-11.785508155822754 -757,757,R63V,-0.001262943,0.03592568,0.00911717,-0.023027042,-1.337554196,-0.001112964,0.037181537,-0.039707422,-0.007937356999999999,0.009470619,0.062380740999999996,-0.026630767000000003,0.044865105999999995,-0.028372612000000002,-0.017681471,-1.0914258479999999,-1.583682543,0.818372951,1.3634916380000002,-8.13818463,-8.896631371,-8.290886726,-8.102747215,-7.6903937529999995,-7.710264083999999,-5.672094502999999,-1.936902207,-9.294646263122559,-7.580904960632324,-10.215888977050781,-11.404858589172363,-12.4485445022583 -758,758,R63Y,-0.035078013,0.073713263,0.022152567,0.013112338000000001,-1.305136837,-0.021424274,-0.040634627,-0.029521397999999997,-0.055383349000000005,0.075605498,0.071821028,0.059356294000000004,-0.01505116,0.10036246900000001,-0.074137794,-0.933605885,-1.6766677890000001,0.46229254399999997,1.334906535,-8.670783517,-10.26926845,-8.456500748,-9.059950462,-8.572810555,-6.995387375,-6.1590945,-4.424966096,-12.32366943359375,-9.50626277923584,-11.795188903808594,-12.57802963256836,-11.674208641052246 -759,759,F64A,0.013724988999999998,-0.40015947799999996,-1.6165436880000001,-2.089278195,-3.3888094310000003,0.055516183,0.022542617999999997,0.004907359,,-0.365233708,-0.435085248,-1.673063391,-1.560023984,-2.1443715880000003,-2.034184802,-2.801162415,-3.9764564460000003,2.67816244,0.928730073,-10.31397514,-8.348962143,-10.07585074,-11.10702494,-11.24063365,-10.79740421,-6.627142216,-4.86424536,-9.501381874084473,-15.554354667663574,-11.990215301513672,-12.454595565795898,-14.380594253540039 -760,760,F64C,-0.000465079,-0.101256261,-1.4007833230000002,-2.83977023,-3.4444231860000003,0.06528308299999999,0.049790482000000004,-0.050720639000000005,,-0.053183325,-0.149329197,-1.288717434,-1.5128492119999999,-2.189924656,-3.489615803,-3.1197167560000003,-3.7691296160000003,0.910740673,0.099954217,-12.32212331,-10.94997182,-12.81034616,-11.37790232,-12.93668108,-13.53571516,-7.773932814,-6.185260378,-11.453527450561523,-14.686385154724121,-11.296666145324707,-13.42890739440918,-14.420283317565918 -761,761,F64E,-0.037619673,-1.145113425,-1.972874924,-2.068206371,-3.02234433,0.04696629,0.030016941000000002,-0.10525628599999999,,-1.107199067,-1.183027783,-2.04893611,-1.8968137369999998,-2.132064134,-2.004348608,-2.663916225,-3.380772434,3.45357677,1.13492915,-12.76323986,-10.74397124,-12.83867902,-12.399367999999999,-13.66450612,-14.16967491,-7.655104422999999,-6.177034591,-12.412622451782227,-19.364727020263672,-15.413397789001465,-16.72950553894043,-17.349609375 -762,762,F64D,-0.033295451000000004,-1.9588083569999999,-2.1398885780000003,-2.258098772,-3.075736094,0.030130052999999997,0.018020975,-0.08461187699999999,,-2.012386466,-1.905230248,-1.9998809990000002,-2.279896157,-2.42979651,-2.086401033,-2.484527346,-3.666944842,2.515367619,-1.59410191,-15.8982201,-13.49726414,-17.40789885,-15.25777419,-17.42876489,-15.89939844,-9.940877565,-10.09132959,-12.321334838867188,-20.140304565429688,-16.679325103759766,-18.78215789794922,-18.89349365234375 -763,763,F64G,-0.000137964,-1.6692987780000001,-2.055692976,-2.209684094,-3.0805490819999997,0.035771395,0.036574186,-0.036850113999999996,,-1.8067700869999999,-1.531827469,-2.209237968,-1.902147983,-2.116274734,-2.3030934530000002,-2.7730655619999998,-3.3880326010000004,2.0234054930000003,-1.628992269,-14.67804395,-13.71830597,-14.89361069,-14.26991566,-15.71274969,-14.79563773,-9.940877565,-10.09132959,-14.432169914245605,-16.28734588623047,-15.653385162353516,-15.800130844116211,-17.829910278320312 -764,764,F64I,-0.009748666999999999,0.023435532999999998,-1.122824316,-1.8018144319999998,-2.809557375,0.003588868,0.052482182,-0.071979516,,0.011708257,0.035162808,-0.7434720920000001,-1.50217654,-1.87581814,-1.7278107230000002,-2.80561024,-2.81350451,1.961784681,0.865883733,-8.656968736,-8.257107513,-5.8757360610000005,-8.394733559,-10.53141696,-10.22584959,-5.507094298999999,-3.639622919,-10.64278507232666,-11.505851745605469,-9.754544258117676,-10.575379371643066,-11.183420181274414 -765,765,F64H,-0.031702786000000004,-0.37144605399999997,-1.855072162,-2.214719148,-2.635383711,0.005981868,0.034147934,-0.097553506,,-0.281027276,-0.461864832,-1.74724859,-1.9628957340000002,-2.034496598,-2.3949416969999997,-2.487167442,-2.783599979,1.267511246,0.028652333,-12.27170628,-14.91300625,-11.72822225,-8.655014816,-12.59842937,-13.46385873,-6.865003678,-4.1980405869999995,-10.738755226135254,-12.802225112915039,-10.721660614013672,-12.648924827575684,-12.412824630737305 -766,766,F64K,-0.015607968,-0.894579352,-2.123853041,-2.5826838530000003,-3.226927432,0.029842726,0.055787385999999994,-0.087003322,,-1.0088943129999999,-0.78026439,-1.919373662,-2.328332419,-2.553409156,-2.61195855,-2.784231251,-3.669623613,2.422120165,0.290970434,-14.11163622,-12.77386147,-14.10982631,-12.38772823,-15.50184618,-15.78491892,-7.499532143,-5.439412143999999,-12.733175277709961,-19.545513153076172,-14.622337341308594,-15.791391372680664,-15.788002967834473 -767,767,F64M,-0.036484905,0.023722338,-0.01221472,-0.098431851,-1.78343415,-0.026789322999999997,0.001281141,-0.074250951,,0.022417964,0.025026711,0.036704546,-0.061133985,-0.065886885,-0.130976816,-1.572683087,-1.9941852130000002,0.879802373,1.329783233,-8.14933502,-7.332246315,-6.118420456,-7.981533592000001,-9.393772903,-9.920701836000001,-5.80238681,-2.78262693,-9.191276550292969,-12.520893096923828,-8.607940673828125,-10.846746444702148,-10.901176452636719 -768,768,F64L,-0.005539031,0.01245872,-0.9043608759999999,-1.830372352,-2.346558986,0.024664339,0.048682277999999995,-0.059760339,,-0.020268098000000002,0.045185538,-0.6665269220000001,-1.14219483,-1.7468071040000002,-1.913937599,-2.8101381119999997,-1.88297986,2.065758208,0.972251407,-7.5938712420000005,-6.963559631,-5.634145072999999,-7.054276176,-9.176542076,-9.140833252,-5.829044635,-2.5966034330000003,-7.840456008911133,-11.040548324584961,-7.164738655090332,-8.858205795288086,-8.344208717346191 -769,769,F64N,-0.039346988,-1.277772915,-2.5653905480000003,-1.9020828,-3.191343685,0.018422714,-0.004995681,-0.073698294,,-1.146264604,-1.409281225,-1.9788571769999999,-3.1519239189999997,-2.135771416,-1.668394184,-2.843714766,-3.5389726039999996,3.421659296,1.096727314,-16.03152285,-14.51413927,-17.83179681,-13.34323047,-16.68772018,-17.7807275,-9.779764857,-9.352302711,-12.771340370178223,-16.93457794189453,-13.424031257629395,-15.54599380493164,-14.879146575927734 -770,770,F64Q,-0.052006576,0.021362062999999997,-1.062696415,-1.857375187,-2.642892061,0.057610204000000005,-0.00378812,-0.10022503199999999,,0.01913441,0.023589716,-0.919373662,-1.206019167,-1.729500415,-1.985249958,-2.659292514,-2.6264916069999997,2.3711038980000003,1.132025689,-13.54362713,-11.03091702,-13.70962211,-13.08228495,-14.42407352,-15.47123804,-6.738277985,-3.936784335,-10.392378807067871,-16.399473190307617,-11.99570369720459,-12.618629455566406,-11.873153686523438 -771,771,F64P,-0.0023103520000000003,-1.691576636,-2.1925566119999997,-2.3301431,-2.7358260519999997,0.027564906,0.032702596,-0.037323300000000004,,-1.8148368730000002,-1.568316399,-2.2283001380000003,-2.156813086,-2.21451815,-2.44576805,-2.746370241,-2.725281863,2.4151761780000003,-1.31048882,-13.85739738,-13.125532999999999,-14.51842745,-13.34957873,-14.819194400000002,-13.47425335,-7.245096751,-5.700397604,-13.740522384643555,-16.423431396484375,-14.616033554077148,-15.377862930297852,-15.99841022491455 -772,772,F64S,0.005165746,-0.9254701759999999,-2.007173027,-2.422540943,-3.494443125,0.015783174,0.035549408,-0.025217916,,-0.881916945,-0.9690234059999999,-2.206416694,-1.80792936,-2.580814877,-2.264267009,-3.5106069769999997,-3.478279273,1.181513072,-0.444501162,-10.7208713,-10.399001400000001,-10.78474109,-9.711034172,-11.89410161,-10.81547824,-6.903568446,-5.701543528999999,-11.104662895202637,-15.493036270141602,-11.592860221862793,-12.70671558380127,-13.629740715026855 -773,773,F64R,-0.01974513,-1.18384842,-2.144861517,-2.3533201790000002,-3.301163574,0.050730748,0.021924507000000003,-0.061414765999999996,,-1.159270454,-1.208426386,-2.352819469,-1.936903565,-2.300474086,-2.4061662719999997,-2.983593852,-3.6187332960000003,1.271028951,-0.5893832179999999,-13.59526792,-12.70852303,-10.41536175,-11.78033474,-15.43554123,-17.63657888,-6.550318602000001,-4.774481488,-11.27123737335205,-16.70664405822754,-13.350162506103516,-13.502379417419434,-14.535152435302734 -774,774,F64T,0.011485381000000001,-0.202048388,-1.515333579,-2.330658398,-2.630296893,0.012677202,0.035352269,-0.012381507,,-0.10921483300000001,-0.294881942,-1.4316654819999999,-1.599001675,-2.190639713,-2.470677082,-2.530606277,-2.729987509,0.9607310579999999,0.075865773,-10.34940045,-9.705437851000001,-9.03081749,-10.628728500000001,-10.81334212,-11.5686763,-6.517542119,-4.917899263,-11.887725830078125,-15.42540168762207,-12.088122367858887,-13.804464340209961,-13.849196434020996 -775,775,F64W,-0.020653294,-0.003878135,-0.110487266,-1.561012024,-2.549393345,0.014975277,0.010346714,-0.051653302000000005,,-0.028651729,0.02089546,-0.11936574900000001,-0.10160878300000001,-1.345709513,-1.7763145340000002,-2.554255214,-2.544531475,0.9637642809999999,0.745863883,-11.08181953,-11.11045232,-11.88724066,-8.486794876,-12.13695214,-11.78765763,-6.091807964,-3.308432387,-9.662853240966797,-14.473687171936035,-10.350343704223633,-11.621699333190918,-11.834745407104492 -776,776,F64V,0.009114989,-0.007850148000000001,-0.00848575,-1.193081601,-2.270670191,0.0014335139999999999,0.045147071,-0.026917093,,-0.036288634,0.020588339,-0.012297396,-0.004674103,-0.637968115,-1.748195086,-2.223596872,-2.31774351,1.7198634240000001,1.332249403,-7.797226328,-6.115346474,-6.138590279,-8.068065239,-9.556761116,-9.10736853,-5.398436101000001,-2.06766327,-9.32646369934082,-10.373651504516602,-8.510303497314453,-9.665522575378418,-11.5768404006958 -777,777,F64Y,-0.012969563,0.015158217,0.006973345,0.027411037000000003,-1.611485958,-0.023906392000000002,0.011080446,-0.037019572,,0.011277452,0.019038982,0.03856884,-0.02462215,0.036435402,0.018386671,-1.6026266580000001,-1.6203452580000002,0.630179217,1.31220221,-7.542598911,-8.01515918,-9.12860836,-5.57043898,-8.447370796,-6.551417236,-4.2237465,-2.286461081,-7.287668704986572,-10.689611434936523,-7.286128997802734,-9.323602676391602,-10.743550300598145 -778,778,P65A,-0.014314967,0.011552608,0.006077418,0.009572938000000001,-1.414854298,0.036509902000000004,0.009387425,-0.038017358,-0.026162439,0.022363176000000002,0.0007420389999999999,0.012563841000000001,-0.000409005,0.011216921999999999,0.007928953,-1.3937796390000001,-1.4359289569999998,0.9269574290000001,1.34849867,-5.368892606,-5.7930937810000005,-5.586125312999999,-4.344099937,-6.4752117920000005,-4.645932205,-5.053259387,-0.958658655,-4.796236038208008,-7.028815746307373,-7.524843215942383,-6.767490386962891,-5.5000410079956055 -779,779,P65C,-0.024244545,0.029899921,-0.104559116,-1.512368547,-3.03405659,0.140301902,0.003760695,-0.052249785,-0.04895053,0.042251142,0.0175487,-0.076336087,-0.132782145,-1.40714071,-1.6175963830000002,-2.5427104590000003,-3.5254027210000003,0.838573874,0.723701128,-12.71509686,-11.83436613,-12.50607805,-14.04272374,-14.33311012,-10.85920627,-8.46723573,-4.670034299,-11.512801170349121,-12.312992095947266,-11.438828468322754,-12.582756042480469,-14.270394325256348 -780,780,P65E,-0.076936322,0.007836665999999999,-1.08778714,-2.056855574,-3.178608368,-0.011789808,-0.081631614,-0.07224103,0.011787229,-0.009925891,0.025599222999999997,-0.673991837,-1.5015824430000002,-1.962831959,-2.150879189,-2.797371712,-3.5598450230000003,1.8629310769999998,0.8037116940000001,-13.69747834,-12.409296300000001,-15.51843599,-13.97775693,-16.37844583,-10.20345666,-8.786477949,-4.075681959,-12.733148574829102,-13.449448585510254,-10.598997116088867,-12.102946281433105,-12.430978775024414 -781,781,P65D,-0.007828136,-0.512012328,-1.829379806,-1.9509769819999998,-3.0157580989999997,0.036723431,0.019961494,-0.035617765,-0.00619855,-0.362839721,-0.661184934,-1.681390973,-1.9773686380000002,-2.131382003,-1.77057196,-2.664891761,-3.366624437,2.7094122389999997,0.9624097659999999,-14.18483879,-12.55095097,-15.25666372,-15.58529152,-15.53070547,-12.00058225,-9.169106934,-5.394382587999999,-15.002401351928711,-14.509536743164062,-11.83963394165039,-14.349119186401367,-14.865896224975586 -782,782,P65G,-0.021974702999999998,-0.003964627,-0.03512254,-1.671626394,-2.824370872,0.050792686,0.0016784220000000002,-0.045627827,-0.020297183,-0.013286335,0.005357081,-0.06292307,-0.007322009,-1.371077783,-1.9721750040000001,-2.501684112,-3.1470576319999997,0.7038904509999999,0.714856285,-11.1458355,-10.25039447,-11.65426146,-9.963110054,-15.38340816,-8.478003357,-6.856502364,-3.243425637,-11.433920860290527,-10.266733169555664,-10.79421615600586,-11.000502586364746,-11.603506088256836 -783,783,P65F,-0.07672585900000001,-0.022937487000000003,-0.380402994,-1.871867945,-2.646213716,0.073839195,-0.00810489,-0.145346828,-0.20623270300000002,0.032546507999999995,-0.078421482,-0.223213913,-0.537592074,-1.305228159,-2.43850773,-2.382805961,-2.9096214710000003,1.516513564,0.8844115309999999,-13.64491739,-13.57938696,-12.04161774,-17.99358546,-14.26436367,-10.34563309,-8.327905156,-4.784129655,-12.127695083618164,-13.138301849365234,-10.667315483093262,-12.76557731628418,-13.405492782592773 -784,784,P65I,-0.046100929000000006,0.018896786999999998,0.022447619,-2.0884452209999997,-2.414665711,0.014761453999999999,-0.040483537,-0.051718321,-0.11927706099999999,0.042284460999999995,-0.004490888,0.047029071,-0.002133834,-1.6256784309999999,-2.551212011,-1.98309693,-2.846234492,0.590865189,0.687786309,-11.3728154,-10.304407199999998,-11.08411542,-11.46849491,-15.36621362,-8.640845848,-7.781307439,-3.802290053,-10.221221923828125,-11.685477256774902,-11.160072326660156,-10.81242847442627,-12.059488296508789 -785,785,P65H,-0.036473154,0.016670462,-0.016075728,-0.96000361,-2.1949884219999998,0.064508101,-0.004853212,-0.068093095,-0.04557594400000001,0.017317285,0.016023638,-0.031141496,-0.00100996,-0.711383366,-1.208623853,-2.1002103290000003,-2.289766515,1.868632593,1.399528087,-12.07621915,-11.18357777,-10.87283597,-15.87225877,-12.19385343,-10.25856979,-7.679228847999999,-2.672501875,-11.91860294342041,-12.19935417175293,-10.020699501037598,-11.877182960510254,-12.916576385498047 -786,786,P65K,0.011009463,0.030209235,0.06250006400000001,-1.62078334,-2.53504946,-0.009152216999999999,0.056867235,-0.034848309,-0.06884535900000001,-0.048973345,0.109391814,0.034664567,0.090335561,-1.139602333,-2.101964347,-2.451263342,-2.618835578,0.701273183,0.7332867470000001,-13.45046829,-12.50085229,-13.93208151,-13.78073704,-15.97346814,-11.06520245,-7.992176742000001,-4.097087225,-13.05724811553955,-13.122209548950195,-11.862979888916016,-12.575837135314941,-12.477203369140625 -787,787,P65M,0.09840180400000001,0.015083721999999999,-1.290873375,-2.264831718,-2.5910522080000002,0.014229945,0.128848916,0.067954691,-0.008126608,0.020146575,0.010020868,-0.9664055640000001,-1.615341186,-2.2972101869999997,-2.232453248,-2.052568694,-3.1295357210000003,1.816676486,0.48103319299999997,-9.332142043,-8.559300056,-10.01375991,-9.64707238,-12.57203146,-5.86854641,-6.756379475,-4.285118399,-11.125677108764648,-10.64655876159668,-10.921567916870117,-9.849742889404297,-11.761139869689941 -788,788,P65L,-0.014751306,0.014214879,-0.33796622299999995,-1.693614309,-2.303535144,0.017136393,0.021866475,-0.051369085999999994,-0.030692436,-0.010153245,0.038583002000000005,-0.23832504899999998,-0.437607397,-1.5393996269999999,-1.8478289909999999,-2.274554748,-2.33251554,1.360870581,0.7853427009999999,-7.821619812000001,-7.305230057,-7.285926399,-7.921430946,-12.9168375,-3.678674156,-4.940324523,-2.7304528660000003,-8.875701904296875,-6.963013648986816,-8.886025428771973,-7.840441703796387,-7.782365322113037 -789,789,P65N,-0.013402401000000001,-0.027247977000000003,0.058529588,-1.1080201440000002,-2.4645895540000002,0.000522434,-0.006257991,-0.02054681,-0.14542164,0.0059861969999999995,-0.06048215,0.074214093,0.042845083,-0.687530799,-1.5285094890000002,-2.044949297,-2.8842298110000004,1.856859485,1.412617518,-13.44981071,-12.46526845,-12.7715477,-15.56986079,-15.57950259,-10.86287403,-8.352456782,-4.6459719569999995,-13.287002563476562,-12.553372383117676,-10.792593955993652,-13.1949462890625,-13.386693954467773 -790,790,P65Q,-0.083736248,-0.053953462,-0.19780773100000001,-1.6085037080000002,-2.323799824,0.108071203,-0.043994341,-0.123478154,-0.031140972000000003,-0.050201259000000005,-0.057705664000000004,-0.15015709300000002,-0.245458368,-1.673866474,-1.543140942,-2.332314969,-2.315284679,1.220030172,0.7381123209999999,-11.99934235,-12.17420722,-13.28824072,-12.35583136,-13.39352733,-8.784905098,-7.75039976,-3.203717795,-11.19420337677002,-10.74355697631836,-9.870216369628906,-9.946479797363281,-10.845489501953125 -791,791,P65S,-0.024183394,-0.003306002,0.012245588,-0.178302774,-1.91444365,0.050568825,-0.010254133,-0.038112653999999996,-0.026142497,-0.009603834,0.002991831,0.012184644,0.012306532,-0.12118336800000001,-0.23542217899999998,-1.5494639780000001,-2.279423321,1.0572590640000001,1.349105188,-10.54720749,-10.15560621,-9.197173599,-11.31379551,-12.92093925,-9.148522903,-7.127304313,-2.671539149,-7.793971061706543,-9.008861541748047,-8.49897575378418,-8.491019248962402,-7.969211101531982 -792,792,P65R,-0.002576072,-0.029280011,-1.41606579,-2.1249131759999997,-2.9158431289999998,0.060691512,0.028468487,-0.033620631,-0.078902444,-0.031363245,-0.027196777000000002,-1.3382761890000001,-1.4938553909999999,-2.040691882,-2.20913447,-3.02649931,-2.8051869480000002,2.385289069,0.9011420509999999,-11.07453513,-11.38429401,-10.62846519,-11.67589157,-13.25863512,-8.425389771,-7.584570327000001,-3.0968600669999997,-11.286317825317383,-11.48006820678711,-10.091317176818848,-11.283886909484863,-12.966957092285156 -793,793,P65T,-0.072020972,-0.015292307,-0.011117082,-1.5643125969999998,-2.386225246,0.034033302,-0.047858254,-0.09618369,-0.011559783999999998,-0.01414397,-0.016440643,0.021652362,-0.043886525999999995,-1.265430107,-1.8631950869999998,-2.241847019,-2.530603473,0.828908773,0.7360786909999999,-10.03961451,-9.303601517,-10.05400492,-10.78871479,-11.48953835,-8.562212959,-7.317749571,-3.0939946369999998,-9.655607223510742,-10.471128463745117,-9.947820663452148,-9.698864936828613,-9.859867095947266 -794,794,P65W,-0.015388326,-0.284308487,-1.689654983,-2.598446441,-3.339318818,0.034518468,0.007471455,-0.038248106000000004,-0.042449308,-0.17504486600000002,-0.393572108,-1.712091225,-1.667218741,-2.7641422469999997,-2.432750635,-2.9966220089999998,-3.6820156269999997,0.9154709940000001,0.003368363,-15.29183539,-13.81318473,-16.33257647,-17.13588286,-17.25705077,-11.92048213,-9.924382312,-6.361046556,-13.396390914916992,-15.933595657348633,-11.77448558807373,-14.563657760620117,-15.495591163635254 -795,795,P65V,-0.005848987,0.058583367000000004,0.06395485599999999,-0.9910799309999999,-2.5603555140000003,0.08815465800000001,0.014186596999999999,-0.02588457,-0.053251362000000003,0.041765019,0.075401715,0.055776899000000005,0.072132812,-0.560689622,-1.42147024,-2.116976595,-3.003734433,1.6473824330000002,1.352200184,-9.650531458,-9.659339775,-9.283623412999999,-9.695755516,-13.65193146,-5.9620071260000005,-6.960253441,-2.109906444,-8.24156379699707,-9.655695915222168,-9.08690071105957,-9.33994197845459,-9.841182708740234 -796,796,P65Y,0.059737517000000004,0.092076196,-0.244196248,-1.675778328,-2.809710795,0.039512484,0.10855932199999999,0.010915712,0.048510036,0.066164981,0.117987411,-0.18446132399999998,-0.30393117199999997,-1.554575681,-1.796980975,-2.486025448,-3.133396142,1.110789443,0.7382532070000001,-14.72559443,-11.97753706,-14.41857256,-19.43801533,-15.45878616,-12.33506106,-7.680588175,-2.414636544,-13.040807723999023,-14.796751022338867,-9.587966918945312,-13.325150489807129,-13.82254409790039 -797,797,M66A,-0.018477378,0.015334467,0.015844945,0.023224095,-1.654670825,0.044304058,0.008395577,-0.045350333,-0.074818127,0.006055871,0.024613062999999998,0.042062311,-0.010372422,-0.0022962029999999997,0.048744392000000004,-1.42687073,-1.88247092,0.665805741,1.322857457,-8.612746361000001,-9.629804688,-9.860213493,-9.35600885,-6.553660881,-7.6640438920000005,-6.247542482,-0.555128583,-11.21311092376709,-12.740354537963867,-6.640451431274414,-10.141515731811523,-9.772771835327148 -798,798,M66C,-0.041226202,0.017245418000000002,-0.003129543,0.009030523,-1.526861034,0.0035425340000000004,-0.060026919000000005,-0.022425484,-0.146891285,-0.027828534,0.062319369000000006,-0.0008979810000000001,-0.005361105,-0.04935892099999999,0.067419967,-1.503323311,-1.550398757,0.723806815,1.322689162,-12.35013934,-12.23689363,-12.48839301,-13.02649379,-10.435170900000001,-13.56374538,-7.758691001,-6.044103914,-12.524642944335938,-14.112422943115234,-8.426453590393066,-11.931001663208008,-9.673372268676758 -799,799,M66E,-0.04590084,-0.20613688,-1.537494224,-2.19368571,-3.077086547,0.067039456,-0.009428305,-0.082373375,-0.119810341,-0.045585838,-0.36668792200000005,-1.270989557,-1.80399889,-1.9979276590000001,-2.389443761,-2.470649199,-3.683523895,2.7589069189999997,1.251685956,-13.00370005,-13.92857339,-12.7732355,-13.51667011,-10.24239192,-14.55762933,-8.243294148,-6.817865587999999,-12.22163200378418,-17.472436904907227,-9.683602333068848,-12.148895263671875,-12.409915924072266 -800,800,M66D,-0.040833646,-1.52638438,-1.972504373,-1.978479937,-3.33080682,0.023599262000000003,-0.025637942,-0.05602935,-0.247594145,-1.426013919,-1.62675484,-2.054452452,-1.8905562930000002,-2.076668221,-1.880291652,-3.072268505,-3.5893451339999998,3.351215222,0.901056436,-14.40108427,-14.23587167,-14.45002978,-14.63805569,-11.39648042,-17.28498377,-9.455016926,-9.27429895,-15.639433860778809,-18.65519905090332,-11.959518432617188,-12.423543930053711,-13.301982879638672 -801,801,M66G,-0.053145705999999994,0.010669431000000002,0.001864735,-0.06405898,-1.892259959,0.055041003,-0.032001964,-0.074289448,-0.065162076,0.034804966,-0.013466104,0.042681817000000004,-0.038952347000000005,-0.06396408,-0.06415388,-1.7294825719999998,-2.055037345,0.7256021359999999,1.3123832340000001,-12.96721904,-12.65463089,-12.38970042,-13.51684748,-10.319788599999999,-15.95512783,-6.823025425,-4.848255533000001,-15.063017845153809,-16.672489166259766,-9.129042625427246,-14.128545761108398,-12.339216232299805 -802,802,M66F,-0.025169407999999997,0.048467643,-0.0038113279999999997,0.015262598999999998,-0.487952175,0.07727566599999999,-0.022324929,-0.028013887,-0.055781329000000004,0.04607116,0.050864125999999996,0.016816283,-0.024438937999999997,-0.040311711,0.070836909,-0.35208611700000003,-0.6238182329999999,1.300046517,1.8325226419999998,-7.7777883,-7.1223746189999995,-5.873723991,-7.536209502999999,-7.44499865,-10.91163474,-3.45479496,-1.561841817,-8.145376205444336,-10.182754516601562,-4.431029319763184,-7.314125061035156,-6.643272399902344 -803,803,M66I,0.027529546000000002,-0.030403865,-0.021759397000000003,0.020276405,-0.17614582899999998,-0.05477336,0.02508021,0.029978882000000002,-0.064598962,-0.058242715,-0.002565014,-0.008828951,-0.034689843,-0.034540066,0.075092875,-0.09840518300000001,-0.253886475,1.3503311830000002,2.292463867,-4.471891563,-3.765870277,-4.51866745,-4.700688598999999,-3.424503555,-5.949727936,-4.24406619,-2.3576114319999997,-7.029102325439453,-8.150952339172363,-6.359961986541748,-7.286866188049316,-7.118638038635254 -804,804,M66H,-0.024175019,0.000533706,-0.014147416999999999,-0.0485973,-1.920554511,0.042019846,-0.000578877,-0.04777116,-0.082013703,-0.009057119,0.010124530999999999,-0.01685438,-0.011440453,-0.059507278,-0.037687321,-1.78621729,-2.054891731,0.906948565,1.3177517220000001,-11.68956298,-10.35392963,-10.24130968,-13.27693059,-9.595164665,-14.98048032,-5.458169513,-3.037527056,-11.464292526245117,-11.212554931640625,-7.901177883148193,-10.411026000976562,-8.461770057678223 -805,805,M66K,0.013453243,-1.365852074,-2.353720856,-2.4491384999999997,-3.093978709,0.060589000999999996,0.042931791,-0.016025305,-0.20062876600000001,-1.5059725419999999,-1.225731605,-2.244286065,-2.463155647,-2.5217743390000003,-2.37650266,-2.4381933780000002,-3.74976404,0.712534115,-0.959377521,-13.30454448,-13.74884412,-13.64579363,-14.08646209,-10.12295575,-14.91866682,-9.380420642999999,-8.976044596,-12.312070846557617,-16.398601531982422,-10.408548355102539,-12.596094131469727,-12.27123737335205 -806,806,M66L,0.010496515,0.011515403,0.02121233,0.008152147,-0.054318447,-0.009960666,0.0062425,0.014750528999999998,-0.073227303,0.0037234509999999996,0.019307355,0.033918365,0.008506295,-0.033652615,0.049956908,-0.020482383,-0.08815451,1.216325745,2.462144269,-1.534105042,-1.114103386,-1.735543365,-1.83298275,-0.36744783799999997,-2.6204478680000003,-1.790923645,-0.6264706760000001,-5.016140937805176,-6.25437068939209,-2.3273444175720215,-6.8324198722839355,-5.35615348815918 -807,807,M66N,-0.059014943,-0.034475008,-1.2675028959999999,-2.050948181,-3.0302917810000003,0.034619947000000005,-0.042977175,-0.075052711,-0.008511418,-0.03463768,-0.034312335,-1.072011606,-1.462994186,-2.0655032230000003,-2.036393138,-2.981922262,-3.0786612989999997,2.1823411459999997,0.842551809,-14.05437822,-13.42929005,-13.05202569,-14.67120139,-10.83099105,-18.28838294,-9.455016926,-9.27429895,-13.110790252685547,-14.334976196289062,-9.135787010192871,-12.546285629272461,-10.002935409545898 -808,808,M66Q,-0.023585763,0.024812324,0.02141854,-0.082957833,-2.0392695830000003,0.050383575,-0.003667515,-0.04350401,-0.075899808,0.032253262000000005,0.017371386000000003,0.05655039,-0.013713311,-0.07541945,-0.090496215,-1.760934354,-2.317604812,0.8139777109999999,1.3133996190000001,-9.611465596,-10.95479543,-9.378733978,-9.685070595,-6.582183655,-11.45654433,-5.483093729,-2.453323429,-9.719573020935059,-12.205949783325195,-6.410280227661133,-8.256233215332031,-8.861922264099121 -809,809,M66P,-0.019193346,-0.519333527,-1.693169217,-2.169857775,-3.1022491239999996,0.044302247999999995,0.0013297029999999998,-0.039716394,-0.016076137,-0.42440564399999997,-0.614261409,-1.614595864,-1.77174257,-2.0927435880000003,-2.246971962,-2.8542606669999997,-3.35023758,2.7025196910000004,0.9724709999999999,-11.38778756,-11.95941073,-11.52832517,-12.8295838,-9.15344973,-11.46816839,-6.206685912999999,-3.320250778,-12.094619750976562,-12.712076187133789,-8.374704360961914,-10.898520469665527,-13.301328659057617 -810,810,M66S,-0.022181653,0.035280097999999996,0.00772585,-1.4834083180000002,-2.363766686,0.017875811999999998,0.000625946,-0.044989250999999994,-0.075959506,0.041143001,0.029417194,0.016819133,-0.001367433,-1.162779884,-1.804036751,-2.170279392,-2.55725398,0.652395837,0.726664005,-10.50641447,-9.624621552,-9.976209557,-11.21477529,-6.906093772999999,-14.810372199999998,-5.282427157,-1.155982599,-11.692301750183105,-13.255831718444824,-6.685534954071045,-10.909268379211426,-8.515485763549805 -811,811,M66R,-0.026070605,-1.2988736570000001,-2.107423854,-2.581857978,-3.001973273,0.070585812,0.00385321,-0.05599442,-0.118329539,-1.349031637,-1.248715677,-2.17522049,-2.039627217,-2.526494978,-2.637220978,-2.795096534,-3.208850012,0.5670582160000001,-0.814341546,-13.55384705,-13.99313988,-13.32657004,-14.23486736,-10.65178967,-15.56286829,-9.455016926,-9.27429895,-12.48892593383789,-16.084644317626953,-10.386026382446289,-12.98252010345459,-11.624309539794922 -812,812,M66T,-0.018051513999999998,0.025649935,0.018232183,0.006369444,-1.4201589369999998,0.044127829,-0.012861124,-0.023241902999999998,-0.095227956,0.011312359,0.03998751,0.004327924,0.032136442,-0.033258015,0.045996902,-1.4250037009999998,-1.415314173,0.825793265,1.335626323,-7.4558965,-7.432700302000001,-7.462693237000001,-8.288435852000001,-5.184290459,-8.911362647999999,-4.81611863,-1.394418984,-9.066466331481934,-10.916022300720215,-6.939079284667969,-9.620479583740234,-9.209695816040039 -813,813,M66W,-0.031820963,-0.475738042,-1.636609335,-2.347251439,-3.355591012,0.019395275,-0.021396135,-0.042245791,-0.09466632,-0.40083401,-0.550642074,-1.574982534,-1.698236135,-2.454530799,-2.239972078,-3.274039824,-3.4371421989999997,1.637561852,0.18360102399999997,-13.12873119,-12.91194832,-12.24995651,-12.81023176,-11.83610061,-15.83541877,-8.452370444,-6.928005902000001,-12.152535438537598,-15.448846817016602,-7.611791133880615,-12.481513023376465,-9.389229774475098 -814,814,M66V,-0.002282773,0.038642623,0.019164912,0.0038475479999999997,-0.09895059199999999,-0.012662831000000001,-0.00591711,0.001351564,-0.129880203,0.023072669,0.054212576,0.032630157,0.005699666,-0.033314116,0.041009212,-0.076054262,-0.121846921,1.458404071,2.473539228,-4.831133493,-4.7538431469999995,-4.989405518,-4.673658211,-3.351921959,-6.386838631,-3.848031878,-2.869577149,-7.641950607299805,-9.290401458740234,-6.532691478729248,-9.348292350769043,-8.017844200134277 -815,815,M66Y,-0.047952653,-0.016218226999999998,0.011545639,-1.324359782,-2.749518565,0.031386775,-0.028981444,-0.066923862,-0.15042491300000002,-0.006253870999999999,-0.026182583,0.022239459,0.000851819,-0.962782125,-1.6859374390000001,-1.987540639,-3.51149649,2.154303806,1.523136309,-12.07770012,-11.28361041,-10.12142515,-12.26257404,-11.15295093,-15.56794007,-5.329543049,-1.60126592,-10.937366485595703,-14.744476318359375,-6.337430953979492,-9.884057998657227,-5.884769916534424 -816,816,M67A,0.041274409,0.036463102000000004,0.045381773,0.022448772999999998,-0.004768182,0.039407992,0.019126682,0.06342213599999999,0.08002034400000001,0.025041987999999998,0.04788421599999999,0.070941746,0.0198218,0.019798996,0.02509855,-0.03101826,0.021481896,1.114053806,2.46394564,-5.97247477,-4.994473778,-6.342070435,-5.407921165,-7.179390274,-5.938518196,-2.967422985,2.502068199,-4.435825347900391,-7.301090240478516,0.8052620887756348,-5.824520587921143,-5.045041084289551 -817,817,M67C,-0.285901642,-0.267102143,-0.16261510199999998,-0.10086360800000001,-0.247812065,0.49139832899999997,-0.34171776200000004,-0.230085522,0.42593016100000003,-0.031570854,-0.502633431,-0.10148486,-0.22374534399999998,0.016894958,-0.218622173,-0.14774885199999999,-0.34787527700000004,1.308930301,2.1096855469999998,-6.574272098,-6.503120781,-5.065774162,-7.185726494,-7.088285362000001,-7.02845369,-3.69076917,1.688979744,-4.196468353271484,-6.050139427185059,0.5078654289245605,-2.624253273010254,-4.177301406860352 -818,818,M67E,-0.021812481,0.015047528000000001,0.021335597999999997,-1.607073473,-2.184542596,-0.021067369,-0.011352008,-0.032272954,0.025435554,0.049924562,-0.019829507,0.076054445,-0.03338325,-1.442590256,-1.771556689,-2.319767662,-2.04931753,0.520289223,0.6978219370000001,-10.33133629,-8.715245888,-8.069143341,-10.50625233,-13.17024632,-11.19579358,-5.841744052999999,-2.767698938,-11.914129257202148,-12.408681869506836,-6.318532466888428,-7.699484825134277,-7.1112823486328125 -819,819,M67D,0.033463157,0.047099423,0.043524402999999996,-0.058463889000000005,-2.2856503409999998,0.053031825,0.051791422999999996,0.01513489,0.11734982099999999,0.038298975,0.055899871,0.041008891,0.046039915,0.00960841,-0.126536188,-1.87474758,-2.696553101,0.739872275,1.304311377,-8.026353607,-6.453738846,-7.234649277000001,-8.624408463,-9.255814888,-8.563156563,-5.1695256469999995,-2.959472503,-10.154052734375,-13.160013198852539,-6.97631311416626,-8.221802711486816,-9.202495574951172 -820,820,M67G,0.043927488,0.03253344,0.035252797999999995,0.016393647,-0.03955652,-0.10248272800000001,0.010940336,0.07691464,0.074948537,0.023312764,0.041754116,0.044393691,0.026111904,0.021796616,0.010990678,-0.038998372,-0.040114667,1.182770114,2.426226416,-8.374982378,-7.279254066,-7.356561828999999,-8.660215263,-9.164696807999999,-9.414183922000001,-4.518103308,-1.054475656,-9.116052627563477,-9.877923965454102,-1.2683180570602417,-8.27872085571289,-9.129068374633789 -821,821,M67F,0.083709323,0.064480916,0.050637205,-1.0484920979999999,-2.040629435,-0.002909219,0.09671405699999999,0.070704589,0.039849986000000004,0.04480338,0.084158451,0.04615864099999999,0.055115767999999996,-0.7513720209999999,-1.345612174,-1.892342697,-2.188916173,2.011203346,1.518490046,-8.910077664,-9.151378532,-7.665790993,-7.519482704,-10.58444021,-9.629295883,-6.08864444,-3.720615376,-7.893266677856445,-11.307579040527344,-5.176640510559082,-5.91900634765625,-6.798521041870117 -822,822,M67I,0.008764232,-0.013699198000000001,-0.030579772,-0.009333499,-1.283578119,-0.09929467,-0.002336164,0.019864628,0.081716572,-0.006034527,-0.021363869,-0.011122473999999999,-0.050037069,-0.019892219,0.001225222,-1.20627444,-1.360881798,0.7750165940000001,1.345960645,-6.617888905,-6.457860329,-7.277482704,-6.5740772089999995,-7.172036583,-5.607987701,-6.863258047,-4.339873322,-7.179245471954346,-8.113909721374512,-5.545461177825928,-5.833778381347656,-6.592574596405029 -823,823,M67H,0.038810047,0.019228775,0.03650962,0.033339062999999995,-1.556438761,0.022097475,0.009823917,0.067796176,0.03354875,0.022193486000000002,0.016264063999999998,0.035746942999999996,0.037272297,0.018453227,0.048224897999999995,-1.223871674,-1.889005848,0.710296983,1.33981787,-11.04499814,-8.91560154,-8.178470978,-12.86380316,-13.63545108,-11.63166394,-6.083484284,-2.6776702759999997,-9.794510841369629,-12.273794174194336,-6.5619378089904785,-6.8766350746154785,-7.222539901733398 -824,824,M67K,-0.019451849,-0.179492392,-1.697063716,-2.467942159,-2.9693657910000004,0.017994551,0.004223585,-0.043127282999999995,0.041115673,-0.071502615,-0.287482168,-1.53379377,-1.860333662,-2.87781195,-2.058072367,-2.412566675,-3.5261649060000004,0.7548908590000001,0.03275763,-11.23512407,-10.45568147,-9.470303573999999,-11.65361331,-13.34326442,-11.25275758,-8.390336279,-7.399047766,-11.622413635253906,-13.234956741333008,-9.760523796081543,-9.769853591918945,-11.03962230682373 -825,825,M67L,0.019574852,0.040355645,0.030829856,-0.0034626120000000003,-0.449230009,-0.08222452599999999,-0.007639496,0.046789199000000004,0.055581853,0.048515153,0.032196137,0.059434201,0.00222551,0.020531066,-0.027456289,-0.334647855,-0.5638121620000001,1.03251495,1.675100715,-2.6141165269999997,-3.161647507,-2.426969795,-2.834422585,-1.92611274,-2.721430008,-3.984816939,-0.278442438,-4.546831130981445,-6.093315124511719,-5.272110939025879,-3.141373872756958,-4.790596961975098 -826,826,M67N,0.020804911000000002,0.049890496,0.040865608,0.014451331000000001,-0.007628561,0.08754204300000001,0.005164126,0.036445696,0.079850242,0.041171217,0.058609774,0.081374525,0.00035669099999999996,0.023875828999999998,0.005026832,-0.007977988,-0.0072791340000000005,1.306073461,2.5405053090000003,-4.073840581000001,-3.47325927,-2.68507943,-4.997464272,-5.637300896,-3.576099037,-3.090289505,-0.5211475870000001,-3.762352705001831,-4.801199913024902,-3.270740032196045,-4.724691390991211,-3.9405105113983154 -827,827,M67Q,-0.028106246,-0.012759333000000001,-0.054587134,0.030859851,-1.0989482940000002,0.10563814199999999,-0.008048122,-0.04816437,0.003375917,0.017606296,-0.043124960999999996,-0.035738608,-0.073435659,0.049900512,0.01181919,-0.664378648,-1.533517939,0.6221822929999999,1.384600014,-8.695790123,-6.868628136,-5.749395653,-9.100534874,-10.88453567,-10.87585629,-4.889685237,0.592894728,-6.631697177886963,-8.232538223266602,-3.6658096313476562,-3.8461246490478516,-7.063526630401611 -828,828,M67P,-0.031212695,-1.585740802,-2.344644632,-2.371231389,-2.755756325,0.035931549,-0.012038523,-0.050386865999999995,-0.09502039999999999,-1.6970375359999998,-1.4744440669999999,-2.6498381419999997,-2.039451122,-2.3706070319999997,-2.371855746,-2.604331761,-2.9071808889999997,-0.191687138,-1.1003105359999998,-12.78184855,-12.05338488,-11.65326329,-12.70625984,-14.06418129,-13.43215345,-8.390336279,-7.399047766,-12.337671279907227,-12.667170524597168,-8.940966606140137,-11.919754028320312,-11.184046745300293 -829,829,M67S,0.023886261000000002,0.022876727000000003,0.031380819,0.005506279,-0.10032247,-0.100766495,0.004342735,0.043429787000000004,0.09135996099999999,0.027069972,0.018683481000000002,0.068164167,-0.00540253,-0.004703409,0.015715967,-0.118357445,-0.082287494,1.4010500940000001,2.322254221,-5.3991242999999995,-4.817881859,-4.96699118,-7.487386116000001,-5.431356705,-4.292005638,-3.3683603910000004,-1.1954267440000002,-5.4741668701171875,-6.740926265716553,-1.3156250715255737,-5.959161281585693,-5.01715087890625 -830,830,M67R,-0.02531785,-0.46354768799999996,-1.7714742909999999,-2.217430181,-2.942099013,0.008096506,-0.033688097,-0.016947603000000002,0.035550663999999996,-0.398505349,-0.528590026,-1.747224902,-1.795723679,-2.233910586,-2.200949775,-2.7686653110000004,-3.115532714,1.4266738819999998,0.053629948,-13.62442921,-11.7496193,-11.73669692,-14.00280697,-15.77527293,-14.85774992,-8.390336279,-7.399047766,-13.262380599975586,-14.042896270751953,-8.67119026184082,-9.894255638122559,-10.481666564941406 -831,831,M67T,0.02386907,0.013818978,0.050287824,0.012335575,-0.062693547,-0.082457579,0.008068071,0.039670067999999996,0.050768912,0.025340032000000002,0.002297923,0.050203033,0.050372614,0.001294481,0.023376668,-0.060961919,-0.064425174,1.301915003,2.424270789,-4.841839943,-5.136262032,-4.113960815,-5.284327385,-5.621512207,-4.053137276,-3.7563991989999996,-1.265326492,-1.4418158531188965,-5.016488075256348,-1.6560643911361694,-5.866953372955322,-7.083711624145508 -832,832,M67W,-0.012379145,-0.6082582639999999,-1.70148854,-2.163975358,-2.776323366,-0.027639429,-0.005823961,-0.018934328,0.0063556509999999995,-0.549179964,-0.667336564,-1.638668789,-1.7643082909999999,-2.271482508,-2.056468208,-2.505207238,-3.047439493,2.95324871,1.105490899,-11.54143914,-11.13045979,-9.94939344,-10.4027261,-13.54849153,-12.67612483,-7.560676787,-5.021316166,-12.178611755371094,-14.054129600524902,-7.720848560333252,-8.188740730285645,-6.235700607299805 -833,833,M67V,0.029725297999999997,0.020631657,0.03641298,0.0171589,-0.20580358199999998,-0.09598597199999999,0.009751423,0.049699173,0.023234506000000002,0.024394469,0.016868843999999997,0.064277188,0.008548772,0.017740041,0.016577758999999997,-0.179142174,-0.23246498899999998,1.276108129,2.072543987,-7.083968565,-6.014704688999999,-6.527889762999999,-5.819602493,-6.68602433,-10.37162155,-5.1238031369999995,-2.918821228,-6.785584449768066,-8.24819564819336,-4.153112411499023,-6.401190280914307,-7.6382317543029785 -834,834,M67Y,0.059796775,0.002666973,-1.373296289,-2.083085674,-2.869177379,-0.038763141,0.041272863,0.078320686,0.060616347,-0.007079894000000001,0.01241384,-1.415812457,-1.3307801209999999,-2.127807422,-2.038363925,-2.75947216,-2.978882598,2.300551988,0.8052038,-10.50726689,-10.35554903,-9.286521339,-9.392553848,-12.1698839,-11.33182632,-6.259522166,-2.337421261,-8.997546195983887,-13.191826820373535,-5.659993648529053,-7.186995983123779,-6.369156360626221 -835,835,S68A,-0.000202248,-1.564852456,-1.954407739,-2.211910343,-3.369026655,-0.101700699,-0.015787593,0.015383097,-0.175361047,-1.614956894,-1.5147480180000001,-2.050105244,-1.858710233,-2.104798917,-2.3190217680000003,-3.1558991880000002,-3.5821541210000003,0.64191049,-0.9886236429999999,-8.134089592,-8.392843658,-9.032691727000001,-7.309401955,-7.639710365,-8.295800255,-7.257221025,-7.241972444,-14.371209144592285,-13.468961715698242,-11.9528226852417,-11.02722454071045,-13.90593147277832 -836,836,S68C,-0.057817662,-0.312383092,-1.8557062830000002,-2.006392902,-2.383237094,-0.00892494,-0.033056525,-0.082578798,-0.024827425,-0.149977208,-0.474788975,-1.6821284580000002,-2.029284107,-1.6933564380000001,-2.319429365,-2.139119008,-2.62735518,3.851583142,2.221694085,-9.060234192000001,-9.875024559,-10.09069373,-7.291008262999999,-9.264254524,-8.78018988,-6.985296891,-6.250451757,-13.135272979736328,-15.890079498291016,-13.255422592163086,-12.539831161499023,-13.79269790649414 -837,837,S68E,-0.05927591,-2.233223929,-2.6070489340000003,-2.90825055,-3.3581587610000003,-0.10569701699999999,-0.051224825999999994,-0.067326993,-0.284920526,-2.74268016,-1.723767698,-2.792477629,-2.421620238,-2.8037056089999997,-3.0127954910000003,-3.0531735330000003,-3.6631439880000003,1.3066407420000001,-1.679156348,-11.38701376,-11.12287834,-11.64882794,-10.37232729,-11.30070462,-12.49033062,-9.121662103,-11.46630438,-16.541458129882812,-20.123146057128906,-18.52590560913086,-19.91061782836914,-20.350879669189453 -838,838,S68D,-0.048039022,-1.7857265969999998,-1.9807131869999999,-2.441294185,-3.192232391,-0.091213523,-7.120000000000001e-05,-0.09600684300000001,-0.23719365399999998,-1.95602497,-1.615428223,-2.306852434,-1.654573939,-2.318080414,-2.564507955,-2.868578335,-3.5158864469999997,-0.119915058,-1.2055321490000002,-10.70382442,-10.04070176,-11.36037969,-9.600171989,-10.84679685,-11.67107182,-8.253840805,-8.223226532,-16.55479621887207,-19.79401397705078,-17.762985229492188,-18.52656364440918,-17.886178970336914 -839,839,S68G,-0.00796827,-1.5669669380000002,-2.1706188859999997,-2.325082074,-2.577396086,-0.108952193,0.00386237,-0.019798909,-0.15758107300000002,-1.567172159,-1.566761716,-2.223350992,-2.11788678,-2.456427722,-2.193736426,-2.404865651,-2.74992652,0.08555689699999999,-1.0517985029999999,-6.75427664,-6.529896132999999,-7.804829971,-5.287579018,-6.818053932000001,-7.331024147000001,-6.142949400000001,-4.624739989,-15.233014106750488,-13.15958023071289,-13.22934627532959,-12.06781005859375,-15.638175964355469 -840,840,S68F,-0.033700172,-1.458205662,-2.3470122780000002,-2.08304701,-2.8595614769999997,0.011023213,0.0039367840000000005,-0.071337128,0.177492533,-1.4948031259999999,-1.4216081969999999,-1.942540603,-2.751483952,-1.7776773240000001,-2.3884166959999997,-2.504266503,-3.214856451,-0.467134612,-0.894969026,-12.54578895,-11.37343853,-14.63639021,-11.00025938,-12.49377458,-13.22508203,-9.121662103,-11.46630438,-12.319515228271484,-19.079565048217773,-14.975762367248535,-15.06309700012207,-16.985170364379883 -841,841,S68I,-0.19269458,-1.0117956559999999,-1.2529634379999999,-1.089912263,-1.65252998,0.028774228,-0.119899659,-0.265489501,-0.12032555,-1.010223079,-1.013368232,-1.435684161,-1.0702427140000002,-1.071248527,-1.1085759990000001,-1.696380066,-1.608679894,4.020810838,2.55242961,-12.16198637,-10.95683016,-14.67990908,-10.63302402,-11.88560139,-12.65456718,-9.096857065,-11.2243909,-17.84408187866211,-20.687578201293945,-18.167316436767578,-15.10555648803711,-17.5593318939209 -842,842,S68H,-0.044997535,-1.681058254,-2.523211925,-2.145922842,-2.9732917569999997,-0.064951907,-0.048955023,-0.041040046000000004,-0.22030750899999998,-1.748006327,-1.614110181,-2.83919648,-2.20722737,-2.00532642,-2.286519263,-2.798862389,-3.147721125,0.19589540600000002,-1.137779366,-11.87977776,-10.895183300000001,-12.78887261,-10.56518916,-11.70219681,-13.44744691,-9.121662103,-11.46630438,-13.796985626220703,-19.72383689880371,-17.483057022094727,-17.533315658569336,-17.296117782592773 -843,843,S68K,-0.07462216,-1.75206569,-2.583552916,-2.646193905,-2.945587118,0.047307876,0.052592873,-0.201837193,-0.124353039,-2.0176818709999997,-1.486449509,-2.368509335,-2.798596496,-2.379737315,-2.912650495,-2.62920524,-3.2619689960000002,-0.282312086,-1.152196194,-11.61756844,-10.81608961,-12.26726938,-10.53206288,-11.52999226,-12.94242806,-9.121662103,-11.46630438,-18.423128128051758,-21.347511291503906,-18.68535041809082,-18.415172576904297,-20.706214904785156 -844,844,S68M,-0.102365858,-2.123151331,-2.5655629319999997,-2.071232245,-2.9275971339999995,0.071377414,-0.09890700699999999,-0.105824709,0.144492273,-1.941047814,-2.305254848,-2.291875278,-2.839250585,-2.303103258,-1.839361232,-2.552571183,-3.302623085,-0.6560267479999999,-1.0809877509999999,-12.11153613,-11.12507278,-13.75415336,-10.70319332,-11.94962793,-13.02563326,-9.121662103,-11.46630438,-17.281587600708008,-19.201976776123047,-18.771381378173828,-15.688525199890137,-20.32960319519043 -845,845,S68L,-0.083205,-1.753647119,-2.47089468,-2.42659576,-3.0815912030000003,0.015773308,-0.07498041,-0.091429589,-0.115341506,-1.875922633,-1.631371605,-2.828810088,-2.112979272,-2.362916813,-2.490274706,-2.913414734,-3.2497676710000003,-0.238838615,-1.13349804,-12.26772008,-11.20908527,-14.11940754,-10.76326065,-12.40191888,-12.84492806,-9.121662103,-11.46630438,-16.47443199157715,-16.800729751586914,-16.445770263671875,-13.987186431884766,-17.376436233520508 -846,846,S68N,-0.14518617,-1.5929050569999998,-1.7114079169999998,-1.7533525630000002,-2.096320864,-0.027951397000000003,-0.07203702099999999,-0.218335318,-0.08959093300000001,-1.5653841999999998,-1.6204259140000001,-1.916211664,-1.506604169,-1.626409648,-1.880295478,-2.176907569,-2.015734159,4.232192503,1.904566711,-10.72556892,-10.46418092,-11.26378371,-9.641133247,-10.83990746,-11.41883926,-8.695813849,-9.295201633,-12.31135368347168,-17.001323699951172,-15.704798698425293,-15.117527961730957,-12.970114707946777 -847,847,S68Q,-0.078034194,-1.779952051,-2.258041605,-2.203640992,-2.89210983,-0.071627005,-0.07738837900000001,-0.078680008,-0.32592159800000003,-1.650285306,-1.909618795,-2.139415468,-2.376667742,-1.974552189,-2.432729794,-2.400111373,-3.384108286,0.58167221,-1.09566034,-11.64948205,-11.04682595,-12.37666847,-10.50819782,-11.47137964,-12.84433836,-9.121662103,-11.46630438,-16.264577865600586,-18.419605255126953,-17.60523223876953,-17.349267959594727,-20.500003814697266 -848,848,S68P,-0.037315548,-1.602907115,-2.123492316,-2.31595196,-3.316045444,-0.00014879299999999998,0.000589705,-0.0752208,-0.09392557800000001,-1.595146315,-1.610667915,-2.189011828,-2.0579728040000003,-2.258231754,-2.373672166,-2.7885262889999995,-3.843564598,-0.08196982,-1.04648909,-10.30732778,-9.763371368,-11.21548335,-8.941861403999999,-10.02911348,-11.5868093,-8.221768715,-8.223226532,-14.382075309753418,-18.16326904296875,-16.872852325439453,-14.481616973876953,-17.715641021728516 -849,849,S68R,-0.0029233909999999996,-1.619947014,-2.125689924,-2.209027256,-2.991039415,0.061159227999999996,-0.002443422,-0.0034033590000000003,-0.188149492,-1.7272773469999998,-1.512616681,-2.277677166,-1.973702681,-2.243147655,-2.1749068559999998,-2.679702223,-3.302376607,-0.330303709,-1.155592843,-11.48284769,-10.79484264,-12.39500203,-10.14673496,-11.05967715,-13.01798167,-8.719616781000001,-9.281815226,-18.394920349121094,-19.61147689819336,-16.63612937927246,-17.22819709777832,-16.76255989074707 -850,850,S68T,-0.058477074000000004,-1.4404749119999998,-1.962027363,-2.087137721,-2.7131371910000004,-0.005313177,-0.068223376,-0.048730771,-0.08367688200000001,-1.674975245,-1.205974579,-1.833917183,-2.090137543,-2.213121948,-1.961153493,-2.638681132,-2.787593249,-0.10277578,-1.065789799,-10.4788174,-10.45119284,-10.81506612,-9.903008537,-10.20273798,-11.0220815,-9.121662103,-11.46630438,-12.38807487487793,-14.254799842834473,-14.845815658569336,-11.650278091430664,-15.915578842163086 -851,851,S68W,-0.055011448,-1.758212307,-2.323615122,-2.158290134,-3.346758972,0.00609287,-0.031404711,-0.078618185,-0.072216837,-1.772041451,-1.7443831630000002,-1.879830866,-2.767399378,-2.037186882,-2.2793933859999997,-2.985624811,-3.7078931319999997,-0.004982928,-1.053660497,-12.38892633,-11.21858965,-13.98785825,-10.87713127,-12.24973358,-13.6113189,-9.121662103,-11.46630438,-18.06399154663086,-20.818531036376953,-18.34072494506836,-17.608549118041992,-13.390617370605469 -852,852,S68V,-0.074445829,-1.85528656,-2.248222883,-2.333742618,-2.5706664619999997,0.014353853,-0.05177004599999999,-0.097121612,-0.17556096,-2.099742763,-1.610830356,-1.994638272,-2.501807494,-2.227715001,-2.439770234,-2.556364172,-2.584968752,-0.390045621,-1.182754695,-11.87420628,-10.96888941,-14.24413394,-10.32636668,-11.49479956,-12.33684179,-9.121662103,-11.46630438,-15.554428100585938,-19.42215347290039,-17.021760940551758,-14.744219779968262,-17.415712356567383 -853,853,S68Y,-0.150662618,-1.672354001,-2.376204974,-2.2258615969999997,-2.976799803,0.063606768,-0.054873477999999996,-0.246451757,-0.15653772300000002,-1.6260820409999999,-1.71862596,-2.374849513,-2.3775604340000003,-2.0850474969999997,-2.366675696,-2.635545418,-3.318054188,0.134915438,-1.064738715,-12.67955283,-11.30107623,-14.63900039,-10.94191851,-12.36932961,-14.14643943,-9.121662103,-11.46630438,-12.158978462219238,-19.729557037353516,-15.136187553405762,-15.92800235748291,-16.591262817382812 -854,854,T69A,-0.051391062,0.01358255,-0.37980828899999997,-1.731622716,-2.759739677,-0.009190565,-0.035710917,-0.067071206,-0.039254142,0.018514753000000002,0.008650346,-0.281389363,-0.478227214,-1.500595076,-1.962650355,-2.494313057,-3.025166296,1.4280416180000002,0.810208919,-7.4155885360000005,-7.942192314,-6.8129936220000005,-8.113622443999999,-7.231685112,-6.977449188,-6.6888790039999995,-3.3535770680000003,-10.730403900146484,-12.070596694946289,-8.957195281982422,-9.085712432861328,-9.089475631713867 -855,855,T69C,-0.048560088,0.034575041,0.005548795,-0.66715546,-1.764699631,0.005658811,-0.050667660999999996,-0.046452515,-0.056485386,0.043410375999999994,0.025739706,-0.011442663999999998,0.022540254,-0.370065231,-0.9642456890000001,-1.6141451180000002,-1.915254143,1.5997046369999999,1.453289965,-12.8616503,-13.46987543,-12.34620876,-11.3408198,-13.63874135,-13.51260616,-8.08551869,-4.144376909,-11.907326698303223,-13.604373931884766,-11.19898796081543,-10.391343116760254,-9.764182090759277 -856,856,T69E,-0.043355236,-0.088709168,-1.57879016,-2.32013121,-3.195768026,0.063972286,-0.044128915,-0.042581556,-0.020549575,-0.037341334,-0.140077001,-1.487317811,-1.670262509,-2.187795065,-2.452467354,-2.625210545,-3.766325507,0.7414875,0.032880436,-15.00102397,-16.20409887,-12.32520458,-14.75901844,-15.33641184,-16.38038609,-11.19462357,-10.07581263,-15.50767707824707,-19.070096969604492,-15.950252532958984,-14.994080543518066,-15.62619686126709 -857,857,T69D,-0.06617922,-1.387517722,-1.994767061,-2.671883298,-3.2653843989999998,-0.033359528,-0.066500928,-0.065857511,-0.005773021,-1.2358574390000001,-1.539178004,-1.973984384,-2.0155497369999997,-2.71067381,-2.633092785,-2.92624054,-3.6045282569999997,0.417008922,-0.73024674,-14.90185895,-16.39866489,-13.05007192,-13.64129629,-15.00879159,-16.41047008,-9.090674767000001,-5.6023147579999995,-15.25139045715332,-19.283493041992188,-16.343549728393555,-13.212319374084473,-15.364564895629883 -858,858,T69G,-0.052395547,0.02712598,-1.0709059909999998,-2.045712326,-2.628796876,-0.001301949,-0.046700667,-0.058090427,-0.032376882999999995,0.024617083999999997,0.029634876,-0.867342851,-1.27446913,-1.978020155,-2.113404496,-2.69242739,-2.565166362,2.018730707,0.831264621,-13.94326667,-15.09630908,-11.5605393,-12.86209894,-15.12925217,-15.06813388,-9.044720475,-4.905328363,-14.461051940917969,-14.79965591430664,-12.424327850341797,-12.442646026611328,-12.958126068115234 -859,859,T69F,-0.071454426,-0.801645658,-1.826176625,-2.111817795,-3.33535459,0.029183406000000002,-0.041299367999999996,-0.101609484,-0.07596699,-0.7054366879999999,-0.8978546270000001,-1.878097444,-1.774255805,-1.915816866,-2.307818724,-2.9764816360000004,-3.694227544,3.178794579,1.23013718,-18.88107499,-20.9565415,-19.76542342,-15.747919400000002,-20.22785215,-17.70763847,-11.19462357,-10.07581263,-14.502201080322266,-17.399511337280273,-14.125419616699219,-14.524658203125,-14.33454418182373 -860,860,T69I,-0.058369356,0.021225322999999997,0.020425741,-0.7242212840000001,-1.685743653,-0.067037395,-0.044487495999999994,-0.072251216,0.051696764000000006,0.034887178,0.007563467,-0.024033356000000002,0.064884838,-0.326826682,-1.1216158859999998,-1.8078850830000002,-1.5636022230000002,1.422318999,1.371617045,-12.75686141,-14.76882069,-13.43002761,-12.12079459,-13.01878021,-10.44588395,-6.941189385,-2.532213831,-9.307130813598633,-13.682256698608398,-8.509668350219727,-9.465755462646484,-8.438331604003906 -861,861,T69H,-0.055628356,0.00255992,0.008900143000000001,0.016494293,-1.6643248519999998,-0.006280895999999999,-0.04337642,-0.067880291,-0.049012375999999996,0.018848731,-0.013728891000000002,-3.9899999999999994e-05,0.017840185,0.071385161,-0.038396575,-1.6231869680000002,-1.705462735,0.6168719579999999,1.310989303,-16.43805279,-17.21791068,-15.03825835,-14.16289599,-17.03076466,-18.74043426,-11.19462357,-10.07581263,-15.1263427734375,-19.345165252685547,-15.728771209716797,-14.830422401428223,-15.883909225463867 -862,862,T69K,-0.04360924,-1.6169576069999998,-2.466101954,-2.2413655130000003,-3.0338366189999997,0.009976759,-0.063254046,-0.023964432999999997,-0.19201864300000002,-1.617659089,-1.616256125,-2.753726042,-2.178477865,-2.490415468,-1.992315558,-2.7059821989999997,-3.361691038,-0.003920767,-1.108293823,-15.38878544,-15.90170132,-14.11138824,-13.64662029,-15.93135444,-17.35286294,-11.18330136,-10.01004175,-16.026403427124023,-19.619800567626953,-15.757052421569824,-16.008434295654297,-17.08983612060547 -863,863,T69M,-0.022017546000000002,0.055746492,-0.081082689,-1.557463218,-2.478653607,-0.058426799,0.019480575,-0.063515666,-0.026086929,0.053433395999999994,0.058059587,-0.149018517,-0.013146861000000001,-1.4329811280000002,-1.6819453080000002,-2.079911622,-2.8773955910000004,2.719901033,1.768657776,-13.0696115,-14.89475561,-14.13879868,-10.62448895,-14.78542579,-10.90458846,-6.639107642000001,-2.798218868,-10.81959056854248,-11.483570098876953,-10.714012145996094,-11.896406173706055,-9.60900592803955 -864,864,T69L,-0.062853535,0.038659222,-0.161206981,-1.68770447,-2.3927494819999997,-0.049850517000000004,-0.040785906000000004,-0.08492116400000001,-0.021045629,0.027796179,0.049522265,-0.18375889199999998,-0.13865507,-1.46384512,-1.91156382,-2.402515534,-2.38298343,1.231737466,0.7715207079999999,-14.17809166,-16.31392998,-14.5168845,-12.60187893,-15.85725185,-11.60051302,-6.458622693,-1.683743159,-11.106841087341309,-13.701154708862305,-10.13967514038086,-11.03602409362793,-9.071444511413574 -865,865,T69N,-0.042633742,-0.084298081,-1.4024180290000001,-2.11060822,-2.71262599,0.037148493,-0.024070145,-0.061197339,-0.035489925,-0.062919052,-0.105677109,-1.2451608859999999,-1.5596751709999999,-2.061031559,-2.16018488,-2.87865828,-2.546593699,2.337664127,0.885571363,-13.67277468,-14.63774023,-12.26824422,-11.90709372,-14.11666958,-15.43412566,-9.62260525,-6.445616418999999,-11.479999542236328,-13.587549209594727,-11.780957221984863,-11.400858879089355,-11.716588020324707 -866,866,T69Q,-0.09942464599999999,-0.306594118,-1.756024139,-2.474744745,-2.361851281,-0.006098008,-0.06501223099999999,-0.133837061,0.061014524,-0.18456717600000003,-0.42862106,-1.583267734,-1.928780544,-2.797078416,-2.152411073,-2.167547106,-2.556155455,1.051096023,0.049428968,-15.16915362,-15.73637352,-13.47614728,-14.12555421,-16.12446354,-16.38322957,-10.2751351,-7.517902377,-13.698172569274902,-17.382558822631836,-14.746315002441406,-14.325459480285645,-14.95284366607666 -867,867,T69P,-0.042198164,0.032175134,0.042512889000000005,-1.2174905870000001,-2.295937358,-0.004651626,-0.02627112,-0.058125208,-0.0017473920000000002,0.037364278,0.02698599,0.045147605,0.039878172,-0.787598797,-1.647382376,-1.9492901459999998,-2.64258457,2.018297907,1.4927788069999999,-14.32250157,-14.69958135,-13.23689788,-13.66708883,-14.95941074,-15.04952905,-9.697991999,-7.2162177320000005,-14.337857246398926,-16.253816604614258,-12.962193489074707,-13.671462059020996,-11.671311378479004 -868,868,T69S,-0.050313877,0.036361528,0.004310094,-0.013557221000000001,-1.8406381859999998,0.023486387,-0.04322986400000001,-0.05739789,-0.012397323,0.04717323,0.025549825,0.0013920620000000001,0.007228125,0.009010725,-0.036125166,-1.493955098,-2.187321274,0.586450482,1.31512768,-5.651851439,-5.665791283,-5.252498199,-4.0726995619999995,-5.423524651,-7.8447435,-5.994508122999999,-2.7574258069999997,-9.637744903564453,-8.86173152923584,-6.878108978271484,-7.197649955749512,-8.82651138305664 -869,869,T69R,-0.033826686,-1.568010718,-1.847191764,-2.254073743,-3.2939003610000004,0.055970303,-0.024817536,-0.042835835,-0.18781065800000002,-1.598592377,-1.537429058,-1.78421811,-1.910165417,-2.324612891,-2.183534594,-3.280542311,-3.30725841,3.238418673,0.7834336009999999,-16.32842711,-17.09460003,-14.5526664,-15.23368475,-16.76773276,-17.99345162,-11.19462357,-10.07581263,-15.663500785827637,-19.916019439697266,-16.57375144958496,-15.920903205871582,-15.180915832519531 -870,870,T69W,-0.10316216199999999,-1.4231170819999999,-2.231793714,-2.2784861480000003,-3.047111258,0.020761900000000003,-0.070104775,-0.136219549,-0.123547929,-1.47615545,-1.370078713,-2.612222404,-1.8513650240000001,-2.34891183,-2.208060465,-2.8655085560000004,-3.22871396,-0.032727358,-1.023125062,-18.16164438,-19.09954415,-18.25193217,-15.66859653,-19.02078509,-18.76736397,-11.19462357,-10.07581263,-17.16413688659668,-21.19462013244629,-18.317310333251953,-17.919164657592773,-14.77894115447998 -871,871,T69V,-0.061436789000000006,-0.003162264,-0.10678744400000001,-1.5211143,-2.701354223,-0.03538301,-0.056362498,-0.06651108,-0.012605493,0.000704102,-0.00702863,-0.14021535400000001,-0.073359533,-1.35524768,-1.68698092,-2.2759447230000003,-3.1267637219999997,1.202639397,0.7856481479999999,-8.008597307999999,-9.979805054,-6.967821853999999,-8.193730782000001,-8.962129936,-5.939498917000001,-6.750349907,-0.717806545,-9.187692642211914,-11.155101776123047,-8.285419464111328,-7.691575527191162,-6.7638773918151855 -872,872,T69Y,-0.06860904400000001,-1.469756981,-2.0047377930000003,-2.160560308,-2.899078715,-0.005256922,-0.028609693,-0.108608395,-0.150470713,-1.407109348,-1.532404614,-2.274330989,-1.735144597,-2.011020415,-2.310100201,-2.7037084,-3.09444903,0.622293826,-0.846502567,-18.55613394,-19.74169462,-18.81442363,-14.95372202,-19.39108913,-19.87974029,-11.19462357,-10.07581263,-14.242372512817383,-20.26443099975586,-16.574867248535156,-15.867116928100586,-14.645832061767578 -873,873,F70A,-0.004612186,0.050537893,0.029291499,0.074641108,-0.061250842,-0.122878254,-0.02403507,0.014810698,-0.021020962999999997,0.00415596,0.096919826,0.034028412,0.024554586,0.07229791099999999,0.076984305,-0.088218805,-0.034282879,1.387359433,2.47471627,-9.085916505,-7.859765274,-9.250729683,-11.84438702,-8.687853409,-7.7868471370000005,-5.254639149,-2.937827005,-10.906167984008789,-12.075698852539062,-8.778083801269531,-9.92313289642334,-11.717944145202637 -874,874,F70C,-0.05416316,0.027466432000000002,-0.029290387999999997,0.045303395999999996,-0.9926547659999999,0.110081859,-0.03895902,-0.06936729900000001,-0.031885912999999995,-0.010532227,0.065465091,-0.025805582,-0.032775194,0.038891375,0.05171541599999999,-0.794986248,-1.190323284,0.633462878,1.368040107,-9.70662379,-11.02000046,-9.140832565,-10.93694382,-8.813599709,-8.621742393,-6.606571372,-4.25882626,-10.742140769958496,-11.116891860961914,-8.161066055297852,-9.78664493560791,-8.763733863830566 -875,875,F70E,-0.056775489000000005,0.040870582,-1.310980437,-2.169551935,-2.512372906,-0.042740380999999994,-0.03646489,-0.077086087,-0.065977177,0.10544958199999999,-0.023708418999999998,-1.24202729,-1.3799335830000001,-1.9349251680000001,-2.404178702,-2.7905639069999997,-2.234181904,2.486566607,1.047905239,-14.71197794,-14.73395009,-13.098082400000001,-18.06336001,-14.98381199,-12.68068523,-9.729586578,-9.655179711,-14.494640350341797,-17.599225997924805,-13.797853469848633,-13.287178993225098,-17.847198486328125 -876,876,F70D,-0.057271543,-0.79174894,-2.069277197,-1.796583601,-3.155445205,-0.047648490999999994,-0.036093474,-0.078449612,0.033154694,-0.57545041,-1.008047469,-1.736851801,-2.401702592,-1.6281173340000001,-1.9650498680000001,-2.7847860680000003,-3.526104342,3.443525632,1.668194435,-14.55522802,-13.30727068,-12.345147599999999,-18.45786868,-15.05070731,-13.61514585,-9.729586578,-9.655179711,-14.05096435546875,-17.972280502319336,-13.77027416229248,-13.639963150024414,-17.126203536987305 -877,877,F70G,-0.032721237,0.042847095,0.037789718,0.083010457,-1.44172006,0.028137942000000003,-0.02689957,-0.038542902999999996,-0.075631217,0.041485304,0.044208885,0.047634815999999996,0.02794462,0.095280264,0.07074065,-1.238525322,-1.644914797,0.633673665,1.3307198,-10.46870049,-11.74912482,-10.64335997,-10.55234083,-11.06647808,-8.332198769,-5.497358964,-4.427234418,-12.990248680114746,-13.784988403320312,-11.30099868774414,-13.326885223388672,-12.803346633911133 -878,878,F70I,-0.034587296000000003,0.06299980200000001,0.095319636,0.090225895,-1.374392405,0.056843967999999995,-0.028542438,-0.040632153,-0.112185149,0.057008267,0.068991336,0.09051747199999999,0.100121799,0.103582009,0.076869781,-1.4097144659999998,-1.339070344,0.681860812,1.323460689,-9.897836623,-9.229908813,-9.516233757,-12.49029485,-10.20848219,-8.044263504,-5.100540272,-0.555050924,-9.964234352111816,-11.140958786010742,-8.407247543334961,-9.670130729675293,-12.004842758178711 -879,879,F70H,0.052365187,-0.05468426,-0.061522744000000004,8.759999999999999e-05,-0.361345687,-0.125992294,0.00493905,0.099791324,-0.08802128699999999,-0.021398145,-0.087970375,-0.00714718,-0.11589830699999999,-0.058743424,0.05891866,-0.29623535100000004,-0.42645602200000005,1.622583925,2.154389735,-5.177227145,-6.854817268,-3.3937103960000004,-7.376575485,-4.994983261000001,-3.266049316,-4.32094502,-2.801544561,-9.384879112243652,-11.65026569366455,-7.792280673980713,-6.699981689453125,-9.346321105957031 -880,880,F70K,-0.09174729400000001,0.013684257,-1.700638835,-1.9994873530000001,-2.791579503,0.132760471,-0.056071797,-0.12742279,0.078824803,0.036379177,-0.009010664,-1.827512865,-1.573764805,-1.968655871,-2.030318834,-2.2222346180000003,-3.360924387,0.34407118299999995,-0.05179231,-14.57501632,-16.00471822,-12.35072334,-17.20598676,-14.286319599999999,-13.02733366,-9.712055115,-9.558831591,-14.581376075744629,-18.469757080078125,-14.076377868652344,-14.547139167785645,-19.087722778320312 -881,881,F70M,-0.04960317400000001,0.008343828000000001,0.008021333,-0.00483853,0.011483928000000001,0.015716142,-0.037810748,-0.0613956,-0.144008633,0.036276567,-0.019588912,0.05604596,-0.040003294,-0.033090605,0.023413546,0.056879904,-0.033912048,1.136844583,2.7325510630000003,-10.55950328,-9.253477477999999,-10.81630177,-12.77338423,-12.02794076,-7.92641214,-5.740083922999999,-2.077452877,-10.899567604064941,-9.377297401428223,-8.385010719299316,-10.362788200378418,-12.547847747802734 -882,882,F70L,-0.097846925,0.009572438,0.009863398,-0.012687782,-1.86560969,0.005219128,-0.078180837,-0.11751301300000001,-0.066113898,-0.000824729,0.019969604,0.01198491,0.007741886,-0.002924888,-0.022450676,-1.533644555,-2.197574824,0.576926284,1.311734016,-9.765265729,-8.497757942,-10.05480292,-11.72309382,-11.64063809,-6.910035872999999,-6.251001637000001,-4.0886131919999995,-9.53359603881836,-8.83127212524414,-8.288201332092285,-8.523926734924316,-10.94881534576416 -883,883,F70N,-0.143738536,0.024498221,-0.041049122,-0.089691947,-1.799938512,0.02704759,-0.127806358,-0.159670714,-0.080121026,0.01768104,0.031315402,0.020291068,-0.102389311,-0.011379327,-0.16800456600000002,-1.9396880280000002,-1.660188996,0.589376528,1.297059672,-11.74370806,-12.07736552,-9.340758568,-14.58510719,-12.48960138,-10.22570766,-6.907242301,-3.71449954,-12.147621154785156,-13.90004825592041,-10.802757263183594,-10.76016616821289,-12.999544143676758 -884,884,F70Q,-0.026713535,0.008806688,0.033625177,-0.07343553900000001,-2.230348399,0.044918568,-0.027686872,-0.025740198,-0.036549313,-0.006957766,0.024571142,0.03689033,0.030360024,-0.03457497,-0.112296108,-1.67222538,-2.788471417,0.7038462590000001,1.313580535,-13.44462861,-12.29040967,-12.13622935,-17.43158511,-14.40741529,-10.95750362,-9.729586578,-9.655179711,-12.68941593170166,-12.751121520996094,-10.483125686645508,-10.83006763458252,-14.769038200378418 -885,885,F70P,-0.031946444,-1.3527764469999999,-1.83103648,-2.212578135,-2.965079662,0.027865192,-0.015926344,-0.04796654400000001,-0.057243629000000004,-1.326867929,-1.378684965,-1.76035145,-1.9017215090000001,-2.1189784,-2.30617787,-2.3725571469999998,-3.5576021769999997,3.858127207,1.6521478490000001,-14.70290575,-14.9444729,-13.71003355,-17.34600766,-14.61092152,-12.9030931,-9.729586578,-9.655179711,-13.310037612915039,-15.363289833068848,-12.89976978302002,-13.080987930297852,-13.406661987304688 -886,886,F70S,-0.04805045,0.008869864,0.005711616,0.026640992999999998,-0.364725872,-0.007689261,-0.044295339,-0.05180556099999999,-0.027173334,-0.007830619,0.025570346,-0.009098435,0.020521667,0.01015483,0.043127155,-0.283429078,-0.446022665,1.440751537,2.037717133,-7.657532198999999,-8.193356308,-6.9246042789999995,-8.963448715,-5.77989608,-8.426355614,-4.916078079,-2.176951169,-7.088805675506592,-9.061504364013672,-6.979120254516602,-6.975910186767578,-7.6385650634765625 -887,887,F70R,-0.056427094000000004,-0.24058132,-1.8863248959999999,-1.970961728,-2.691720127,0.068760954,-0.038544672,-0.07430951599999999,-0.04613557,-0.179383879,-0.30177876,-2.04776093,-1.7248888619999998,-2.0018172919999997,-1.9401061640000001,-2.7325172939999995,-2.650922959,0.6920005990000001,-0.187892002,-11.52549287,-10.69684155,-9.880773376,-16.26878606,-11.65253188,-9.128531471,-7.594306696,-5.3751034760000005,-14.415735244750977,-16.594388961791992,-12.88200569152832,-13.940963745117188,-17.057186126708984 -888,888,F70T,-0.078416017,0.03029292,0.011951176,0.021167971,-1.718556765,0.060416740999999996,-0.02801184,-0.128820194,-0.006185274,-0.0040831109999999995,0.064668951,-0.032270879,0.05617323,0.038555007999999995,0.0037809329999999998,-1.552078064,-1.885035466,0.611611968,1.313289089,-11.62546475,-11.24747609,-10.53097983,-15.09091251,-10.89615591,-10.36179942,-7.0658564539999995,-4.696843524,-11.439352989196777,-11.105283737182617,-10.381678581237793,-10.522265434265137,-12.578756332397461 -889,889,F70W,0.00234178,0.014628795,-0.008423998,0.011956056000000001,-1.0126441720000001,-0.135875169,-0.007808453000000001,0.012492013,-0.050328684000000005,-0.07418519900000001,0.10344278800000001,-0.039816297,0.022968302000000003,-0.054229658,0.07814177,-0.809753244,-1.2155351,0.9592995129999999,1.4371744830000002,-8.765915517,-8.495728889,-9.498482529,-9.916197746,-8.646312972999999,-7.272855446,-6.161588706,-4.976823612,-9.384140014648438,-10.336966514587402,-9.83038330078125,-10.899168014526367,-11.010395050048828 -890,890,F70V,-0.048794004,0.030406711,0.031028741000000002,0.048168094,-0.037759015,0.024964622000000002,-0.066910194,-0.030677812999999998,-0.052155205,0.028973361,0.03184006,0.036760477,0.025297003999999998,0.052799197,0.04353699,-0.012973468,-0.062544561,1.149243679,2.545344641,-8.432587537,-6.875855286,-8.372665451,-10.90948483,-9.235303627,-6.769628494,-4.603356304,-1.567676314,-10.502826690673828,-9.809242248535156,-7.969745635986328,-9.371953964233398,-12.069175720214844 -891,891,F70Y,0.009889471,0.064875494,0.026559343,-0.039324537,-2.663858905,-0.196552382,0.005555508000000001,0.014223433,-0.0863798,0.046773045,0.082977942,0.073598556,-0.020479871,0.040202272000000004,-0.118851345,-2.138688566,-3.1890292430000002,0.937490681,1.290382178,-4.196971487,-4.12417453,-3.0817318119999997,-5.967478432,-4.058393135,-3.753079529,-3.645805928,-1.6437094330000002,-6.412858963012695,-8.262626647949219,-7.098530292510986,-6.8382182121276855,-8.120624542236328 -892,892,K71A,-0.022341312999999998,-1.3896276230000002,-2.242187535,-2.496077623,-3.5759083,-0.12382122699999999,-0.043061849000000006,-0.0016207770000000001,0.018303515,-1.382603084,-1.396652161,-2.426585325,-2.057789744,-2.289194053,-2.702961192,-3.659214581,-3.492602018,0.041069028,-0.8688970309999999,-7.428212964,-7.521384315,-7.329100876,-7.475908577,-7.37615509,-7.438515961,-7.258929053999999,-6.711949012000001,-16.515644073486328,-15.223931312561035,-11.92343521118164,-14.75564193725586,-17.0091495513916 -893,893,K71C,-0.073174879,-1.501789806,-2.40277975,-2.3903505469999997,-3.20302712,0.22234766399999997,-0.040179269,-0.10617048800000001,-0.069123709,-1.60059405,-1.4029855619999998,-2.102812202,-2.7027472969999997,-2.634427711,-2.146273382,-2.8583202030000003,-3.5477340369999997,-0.023154012,-1.027319465,-9.833668469,-9.787034142000001,-9.912073395,-9.840831795,-9.866564423,-9.761838593,-9.13866872,-11.28944481,-15.975754737854004,-17.216285705566406,-12.240371704101562,-15.823193550109863,-18.820714950561523 -894,894,K71E,-0.029246166,-1.695551181,-1.9481344680000001,-2.687430361,-2.7905422810000005,-0.059911979000000004,-0.026992081,-0.03150025,-0.13143703,-1.641937749,-1.749164613,-2.3038567430000003,-1.5924121919999998,-2.5344422559999997,-2.840418466,-2.758334749,-2.822749813,0.139259825,-1.0596847329999999,-7.981267249,-7.907765251,-8.226845894,-7.9223906479999995,-8.016172028,-7.833162422000001,-7.856059275,-7.526033717000001,-12.330635070800781,-14.677778244018555,-11.50156307220459,-14.115468978881836,-14.489981651306152 -895,895,K71D,-0.053353874,-1.8686496369999999,-2.446777334,-2.622723486,-3.26990345,-0.099993119,-0.045352672999999996,-0.061355075,-0.185107603,-2.028146904,-1.70915237,-2.3542737959999998,-2.539280872,-2.7097980460000004,-2.535648925,-2.933690538,-3.606116361,-0.061271992000000004,-1.191931139,-9.821797421,-9.742821655,-9.761632843,-9.858717918,-9.942163338,-9.803651352000001,-9.13866872,-11.28944481,-13.650846481323242,-16.912023544311523,-12.603361129760742,-16.280881881713867,-15.696261405944824 -896,896,K71G,-0.03267641,-1.741220386,-2.133378725,-2.295687834,-3.385171089,-0.062753908,-0.043356255999999996,-0.021996562999999997,-0.146275538,-1.855477228,-1.626963543,-2.35769538,-1.90906207,-2.220304108,-2.37107156,-2.9882646439999996,-3.7820775330000003,-0.222585842,-1.140412311,-9.797629523,-9.791578461,-9.788956367,-9.84127018,-9.823898353999999,-9.742444252,-9.13866872,-11.28944481,-15.562670707702637,-16.54222869873047,-12.1600341796875,-14.475330352783203,-17.9930362701416 -897,897,K71F,-0.06858913900000001,-1.689206737,-2.1161999,-2.4532557,-2.9164472710000005,-0.11164016199999999,-0.062040106,-0.075138172,-0.209574612,-1.6403918219999998,-1.7380216519999998,-2.3644587230000003,-1.8679410769999998,-1.9418317230000002,-2.9646796760000003,-2.64284547,-3.190049072,0.164857191,-1.107999625,-9.786984508,-9.759945221,-9.778404785,-9.660896065,-9.895395844,-9.840280624,-9.13866872,-11.28944481,-17.385324478149414,-19.74376678466797,-14.545547485351562,-17.165115356445312,-19.416170120239258 -898,898,K71I,-0.01482397,-2.167284589,-2.449879983,-2.335390788,-2.773006099,-0.033942327,0.037021572999999995,-0.066669512,-0.017629088,-2.1218059730000003,-2.212763205,-2.447932866,-2.4518271,-2.201397124,-2.469384452,-2.7263196119999997,-2.819692585,-0.42485301700000005,-1.13637661,-9.816646231,-9.919712357,-9.769868622,-9.803701813,-9.92631575,-9.663632613999999,-9.13866872,-11.28944481,-15.630694389343262,-15.559005737304688,-13.877467155456543,-15.017409324645996,-17.128515243530273 -899,899,K71H,0.002468864,-1.932019025,-2.086978165,-2.424033964,-3.227846154,-0.09548181,-0.01031781,0.015255538,-0.146226987,-2.0566354419999997,-1.8074026069999998,-2.030579816,-2.143376514,-2.738286584,-2.109781344,-2.564239067,-3.8914532410000002,-0.116763868,-1.160365058,-9.82200435,-9.784632712999999,-9.818676369,-9.92590435,-9.805128197,-9.775680122,-9.13039196,-11.20689,-15.606269836425781,-16.773143768310547,-12.441596031188965,-14.614762306213379,-16.546730041503906 -900,900,K71M,-0.069685438,-1.734598039,-2.241739698,-2.553219236,-3.0164108069999997,-0.130262465,-0.07062875099999999,-0.068742124,-0.191056935,-1.898107472,-1.571088605,-2.099295628,-2.3841837669999997,-2.454819878,-2.6516185930000002,-2.67871237,-3.354109243,-0.064607945,-1.1558201129999999,-8.659729297,-8.644042053,-8.774832283,-8.8217836,-8.585026459,-8.47296209,-8.127854018999999,-8.205072427000001,-15.786287307739258,-15.367066383361816,-11.686636924743652,-13.294195175170898,-15.669443130493164 -901,901,K71L,-0.043237132000000005,-1.799813527,-2.1332633690000002,-2.413967028,-3.12361636,-0.107937245,-0.032342666,-0.054131597999999996,-0.159364962,-1.833508226,-1.7661188280000002,-2.1596351190000003,-2.106891618,-2.566311891,-2.2616221640000003,-2.69329437,-3.5539383489999996,0.022446297,-1.130619268,-9.458673164,-9.272165161,-9.710671478,-9.479141151,-9.47148465,-9.359903381,-8.76208769,-9.284504038,-16.15380096435547,-15.98165512084961,-13.24966812133789,-14.096763610839844,-15.470539093017578 -902,902,K71N,0.009434887,-1.4301147280000002,-2.280446826,-2.192749045,-2.8756069639999997,-0.105943152,-0.004832194000000001,0.023701967999999997,-0.081358165,-1.61268255,-1.247546906,-2.592021956,-1.968871695,-2.169394956,-2.216103134,-2.8704087030000003,-2.880805224,-0.19437088800000002,-1.07199181,-9.732415508999999,-9.611261948,-9.731493301,-9.841481155,-9.878447891,-9.59939325,-9.130668229,-11.25349789,-12.888995170593262,-13.431060791015625,-9.101613998413086,-11.019750595092773,-13.663443565368652 -903,903,K71Q,-0.039866595,-1.8159244909999999,-2.730140602,-2.439560149,-3.053266718,-0.09101500900000001,-0.036805781,-0.04292740900000001,-0.163856803,-1.677580777,-1.954268205,-2.702677674,-2.75760353,-2.456141933,-2.422978365,-2.98106442,-3.125469015,-0.071627646,-1.111363545,-8.445954745,-8.241887138,-8.629492958,-8.43746653,-8.492394394,-8.428532707,-8.157069101,-7.997069885,-14.082741737365723,-14.365280151367188,-10.325928688049316,-12.591590881347656,-14.243290901184082 -904,904,K71P,-0.05435827,-1.7667637669999998,-2.103727406,-2.365779742,-3.1227864519999997,0.016499536000000002,-0.042646699999999996,-0.06606984,-0.141233902,-1.799285038,-1.734242496,-2.203572508,-2.003882303,-2.240093391,-2.491466093,-2.9530063610000004,-3.292566542,-0.33409351800000003,-1.144157337,-9.810337882999999,-9.853272964,-9.80120916,-9.720756645,-9.853996841,-9.822453804,-9.13866872,-11.28944481,-17.811542510986328,-15.646049499511719,-14.855560302734375,-16.704952239990234,-16.965572357177734 -905,905,K71S,-0.018584415,-1.5719056569999998,-2.123506915,-2.409903148,-3.743276064,-0.067771768,-0.02312009,-0.01404874,-0.067361863,-1.605658767,-1.538152547,-2.304171563,-1.9428422669999998,-2.5047938530000002,-2.315012443,-3.42765635,-4.058895778,-0.167303383,-1.041359732,-7.956372312999999,-7.867123444,-7.926501854,-7.965756332000001,-8.003749275,-8.018730659,-7.75790133,-7.526033691,-13.27814769744873,-15.403814315795898,-10.541613578796387,-11.640199661254883,-16.0494327545166 -906,906,K71R,-0.074437132,-1.389014437,-2.094399992,-2.26112359,-3.181662996,-0.021993553,-0.07269741099999999,-0.076176853,-0.121209195,-1.32484997,-1.453178904,-2.1199802269999997,-2.068819756,-2.199298065,-2.322949114,-2.7505494919999998,-3.6127764989999998,2.654953805,0.28257444800000003,-7.487875397000001,-7.4284436110000005,-7.592430007999999,-7.420646392999999,-7.530441207999999,-7.467415764,-7.5848181320000005,-7.081301237000001,-13.875911712646484,-14.60754680633545,-9.775728225708008,-11.767807960510254,-15.288634300231934 -907,907,K71T,-0.026357297000000002,-1.6428896590000002,-2.043785169,-2.3016597219999997,-3.0174262830000003,-0.08399859300000001,-0.013035878999999998,-0.039678715,-0.101592363,-1.71301623,-1.5727630869999998,-1.955597071,-2.131973267,-2.010091325,-2.593228119,-2.535013813,-3.499838752,0.11760355300000001,-1.046041142,-6.777715538,-6.723575241,-6.830490097,-6.8930517810000005,-6.7311804120000005,-6.710280159,-6.894332614,-6.444839652000001,-12.751540184020996,-12.348670959472656,-12.638945579528809,-11.930255889892578,-15.704559326171875 -908,908,K71W,-0.003949216,-1.607717082,-2.110874276,-2.47412411,-2.906241728,-0.048581541,0.02034402,-0.028242451000000002,-0.13167921300000002,-1.665534857,-1.549899306,-2.3438442680000002,-1.877904284,-2.699368518,-2.248879701,-2.92326101,-2.889222445,-0.170433277,-1.103846406,-9.808292342,-9.785322731,-9.757114311,-9.850292557000001,-9.874991295,-9.773740814,-9.13866872,-11.28944481,-17.011672973632812,-21.857820510864258,-16.140268325805664,-16.362136840820312,-20.00592803955078 -909,909,K71V,-0.017826069,-1.626137383,-2.300684566,-2.646604749,-3.2603113180000003,-0.109732287,-0.0021448179999999997,-0.03350732,-0.046109345,-1.683720536,-1.56855423,-2.510449779,-2.0909193530000003,-2.440005297,-2.8532042,-2.663897789,-3.8567248469999997,-0.38716672399999996,-1.08008484,-8.73108681,-8.621626999,-8.831675255,-8.730385429,-8.836264099,-8.635482269,-8.489117626,-8.620431725,-16.293893814086914,-15.154786109924316,-13.620817184448242,-15.81479263305664,-19.355884552001953 -910,910,K71Y,-0.060175188,-2.0340453000000003,-2.500629086,-2.837684885,-3.0623158289999997,-0.094350034,-0.029031384,-0.091318991,-0.16761011,-2.151610955,-1.916479645,-2.4777378469999998,-2.523520324,-2.532232102,-3.143137668,-2.7561245939999997,-3.3685070639999997,-0.268920477,-1.200743881,-8.729243103,-8.576681099,-8.748501457,-8.913617149,-8.87844381,-8.528972,-8.559992384,-8.219598506,-15.49892520904541,-18.879392623901367,-14.027750968933105,-17.13753890991211,-18.96099853515625 -911,911,V72A,-0.027805008,-0.015065753000000001,-0.00369984,-0.042274095,-0.856415618,0.059839813,-0.025553332999999998,-0.030056682,0.026489985,-0.027162261,-0.002969245,0.017834445,-0.025234125,-0.031889358,-0.052658830999999996,-0.550051544,-1.162779691,0.834882461,1.46460614,-2.960336475,-1.8283721919999998,-2.903871048,-2.311072868,-3.538372147,-4.219994118,-3.155021867,-0.432795055,-3.617403030395508,-4.315238952636719,-3.6761860847473145,-2.962648868560791,-2.777827262878418 -912,912,V72C,-0.024673567,0.026718226,0.015369262,-0.058745162000000004,-1.496115302,0.056638112000000004,-0.036696621,-0.012650513,-0.006530866999999999,-0.013378896000000001,0.066815348,0.009053057,0.021685467000000003,-0.06154074,-0.055949583,-1.452333778,-1.539896825,0.823601845,1.335695021,-10.09612404,-9.851898949,-8.774846085,-10.73412229,-9.553087067,-11.56666579,-7.795746162,-5.623380455,-6.479028701782227,-8.343657493591309,-8.412967681884766,-7.0962138175964355,-8.960245132446289 -913,913,V72E,-0.227202028,-0.42079340200000004,-1.3713314230000002,-1.4973481069999999,-1.725521981,0.41833993799999997,-0.08809344599999999,-0.36631061,-0.281879642,-0.101826927,-0.7397598759999999,-1.02678006,-1.715882785,-1.110982107,-1.883714106,-1.3097655529999999,-2.1412784080000002,4.016502244,3.16702012,-10.67133559,-10.18014629,-8.616279869,-10.79678746,-10.51672675,-13.24673757,-9.357759313999999,-6.734369282,-9.3326416015625,-12.643240928649902,-10.133116722106934,-11.635839462280273,-10.208122253417969 -914,914,V72D,-0.019572925,-1.6711509080000002,-2.207037043,-2.211534702,-2.711742599,0.052141238,-0.0076789630000000005,-0.031466886,-0.054383993,-1.579723016,-1.7625788,-2.152493631,-2.261580454,-2.060604419,-2.362464985,-2.73650912,-2.6869760769999997,-0.21665399,-1.02881017,-12.12908635,-11.55562926,-10.06414733,-12.511080699999999,-11.59871064,-14.91586384,-10.1347644,-9.125508624,-9.9669189453125,-13.560359954833984,-11.879280090332031,-12.723089218139648,-11.171637535095215 -915,915,V72G,-0.030763272999999997,-0.005612139,-0.205865066,-1.8287566919999998,-2.575720423,0.058110992,-0.017503526000000002,-0.04402302,-0.051147686,-0.022759504,0.011535226,-0.19732456899999998,-0.214405562,-1.571030629,-2.086482755,-2.489973378,-2.661467468,1.335659485,0.7634421690000001,-9.329563174,-9.275374893,-7.726531921,-9.360203484,-8.937884239,-11.34782133,-5.852522545,-2.539726214,-5.950063228607178,-6.903165340423584,-6.317282676696777,-7.2239909172058105,-4.980257034301758 -916,916,V72F,0.001824488,-0.011163712,-0.26707993399999996,-1.475531555,-2.5835393509999998,0.023247317000000003,0.038481053,-0.034832077999999995,0.095796151,-0.0043626129999999996,-0.01796481,-0.20738742,-0.326772448,-1.5064333159999999,-1.444629793,-2.404186766,-2.762891935,1.269366205,0.7756560370000001,-9.344027129,-8.169963165,-6.637502655,-12.31546964,-6.7687313,-12.82846889,-5.940527977,-0.874126842,-2.1345129013061523,-6.774196624755859,-7.979349613189697,-5.181061744689941,-8.143054962158203 -917,917,V72I,0.028744624,-0.024292395,-0.103479614,0.022198371,-0.507858731,0.020444089,0.027932857000000002,0.02955639,-0.074637816,-0.110457259,0.06187247,-0.095767391,-0.11119183699999999,-0.017706378999999998,0.062103121,-0.343135025,-0.6725824359999999,1.394439741,1.9043568990000002,-5.342679185,-6.329724457,-4.718560226,-5.376194122,-5.984338791,-4.304578331,-6.560786592,-0.82323682,-3.573714256286621,-5.930846214294434,-5.706730842590332,-5.894898891448975,-6.0530500411987305 -918,918,V72H,-0.087132349,0.003906718,-1.058058409,-2.225542541,-2.692277041,0.006191825,-0.078674724,-0.09558997400000001,-0.031509414,0.018055938,-0.010242501999999999,-0.721996415,-1.394120402,-2.248155301,-2.20292978,-2.623030005,-2.761524077,1.6682123869999999,0.62249857,-12.57578015,-11.19113375,-9.099641022,-14.76982511,-11.45620301,-16.36209788,-9.37860367,-7.314857802000001,-9.013498306274414,-13.10427474975586,-10.970861434936523,-11.432552337646484,-12.936803817749023 -919,919,V72K,-0.38036411700000006,-1.317882749,-1.291299516,-1.4173162000000001,-1.645490074,0.195761894,-0.369435335,-0.39129289799999994,-0.10295909199999999,-0.813031387,-1.822734111,-0.783742011,-1.79885702,-0.867944059,-1.966688341,-1.0667275040000002,-2.2242526430000003,3.623108256,3.069597641,-11.62049921,-11.93941446,-8.963326172,-11.6359828,-11.19290874,-14.37086386,-10.1347644,-9.125508622,-10.387709617614746,-13.720980644226074,-11.768590927124023,-11.989209175109863,-13.544621467590332 -920,920,V72M,0.05653194,-0.055579535,0.078278454,-1.513848237,-1.892537109,0.108476529,0.035253495,0.077810385,-0.06844824099999999,-0.101826927,-0.009332143000000001,0.134587942,0.021968966,-1.110982107,-1.916714366,-1.610795549,-2.174278668,3.0170069969999997,2.308211273,-7.378028197999999,-7.54708046,-6.271592299999999,-8.296027061,-6.007042952999999,-8.768398216,-5.592804947,-2.672319864,-3.536612033843994,-6.159633159637451,-5.221746444702148,-5.872973442077637,-6.867359161376953 -921,921,V72L,0.003981852,0.040422772999999995,0.017088116,-0.338428524,-1.964738695,0.01399516,0.011487566000000001,-0.003523862,-0.032616707,-0.004403865999999999,0.085249411,0.010286001,0.023890231,-0.201585423,-0.475271625,-1.62488201,-2.304595379,1.210821138,1.363598483,-5.281452625,-5.695308762000001,-5.22336718,-7.091591789,-2.833224014,-5.563771377999999,-5.342466635,-0.0015935139999999999,-1.1674103736877441,-5.916295528411865,-5.707142353057861,-5.049305438995361,-6.909067153930664 -922,922,V72N,-0.06523045,-0.689742614,-1.608409811,-1.918414887,-2.686179384,-0.023621601000000002,-0.04769343400000001,-0.082767466,0.035343606,-0.560306071,-0.819179157,-2.0624956119999998,-1.154324009,-1.845667664,-1.99116211,-2.345481105,-3.026877662,1.265894446,-0.195496007,-12.11868162,-12.17686385,-10.61537549,-12.70920545,-11.06998328,-14.02198003,-10.1347644,-9.125508619,-8.840215682983398,-10.799798011779785,-9.67259407043457,-10.439606666564941,-11.06607437133789 -923,923,V72Q,0.08921719,-0.21184798600000002,-1.602352789,-2.134826151,-2.513515023,0.12575556599999999,0.124290885,0.054143494,-0.069440915,-0.28155247,-0.142143502,-1.95983327,-1.244872307,-1.743005322,-2.52664698,-2.2428187630000003,-2.784211282,3.99561871,2.1994367980000002,-10.73527726,-10.52604308,-9.272590675,-10.38185872,-10.21199604,-13.28389776,-8.920950041000001,-6.736501291000001,-7.9842681884765625,-11.947713851928711,-9.344670295715332,-11.03236198425293,-12.409215927124023 -924,924,V72P,0.031310514,0.010357175,0.022961709,-0.003403723,-0.027108305,-0.044071322,0.003343027,0.059278001,0.004056785,-0.024078678,0.044793027,0.01989516,0.026028258,-0.024468275,0.01766083,-0.031011952000000002,-0.023204657000000004,1.319255397,2.5158700880000002,-5.957245757000001,-5.868305099,-4.896244392,-6.102723,-4.982215675,-7.936740616,-4.776044599,-3.079748695,-6.618505001068115,-7.925537586212158,-7.765710830688477,-8.279407501220703,-8.564279556274414 -925,925,V72S,-0.022299347999999997,-0.010718031000000001,-0.003748603,-0.021408331000000003,-1.4561713019999998,0.013080475,-0.037460104,-0.007138591,-0.059600197,-0.049136424000000005,0.027700363,-0.027279536,0.019782331,-0.000121604,-0.042695057,-1.374223542,-1.5381190619999998,0.741602641,1.332392611,-6.394013899,-5.999102623,-6.190459327999999,-6.6748500139999996,-5.454113898999999,-7.651543632999999,-5.112541195,-3.2991320319999997,-5.12969446182251,-5.601635932922363,-5.022754192352295,-6.147263050079346,-6.145870208740234 -926,926,V72R,-0.041560241,-1.425340606,-1.985458433,-2.195536282,-2.923710155,0.069975753,-0.056358152,-0.02676233,-0.19734413,-1.481700852,-1.368980359,-2.035988062,-1.934928803,-1.89834136,-2.492731203,-3.097124805,-2.750295505,-0.34987106700000004,-1.102522968,-11.83603248,-11.41886273,-10.46571928,-11.66217704,-11.13658121,-14.49682213,-10.1347644,-9.125508613,-10.666572570800781,-14.012237548828125,-12.811798095703125,-12.29653549194336,-14.184694290161133 -927,927,V72T,0.026549943,0.024497295,-0.01619889,-0.0032849000000000003,-0.315691669,-0.013390216000000002,0.019502638,0.033597247000000004,0.014809948,-0.010573648,0.059568237999999996,-0.020976098,-0.011421681999999999,-0.016661145,0.010091346,-0.22993074100000002,-0.401452597,1.186718344,1.900478504,-3.799587802,-5.66988588,-2.409797752,-3.104544868,-2.9296091310000003,-4.884101379,-5.368511167,-1.063179863,-3.8962044715881348,-2.136141777038574,-3.595090866088867,-4.616361618041992,-4.644852638244629 -928,928,V72W,-0.091458333,-0.54702568,-1.65047814,-1.776494825,-2.004668698,0.071646465,0.002669673,-0.18558633800000002,0.006185377,-0.479816708,-0.614234651,-1.295625372,-2.005330908,-1.37982742,-2.173162229,-1.578610865,-2.430726531,4.260887365,2.95946835,-10.12354835,-7.398599464,-8.432560318,-10.76323904,-9.454985306000001,-14.56835764,-5.930063173,-2.9853707330000003,-7.332183837890625,-10.721203804016113,-11.16209602355957,-8.862916946411133,-11.16118049621582 -929,929,V72Y,-0.010121409,-0.759473762,-2.009346254,-1.794742319,-2.713021813,0.049150617,0.02083588,-0.041078698,0.159637271,-0.49451066,-1.0244368640000001,-2.04500488,-1.9736876269999999,-1.8281769319999999,-1.761307706,-2.327990373,-3.0980532530000002,1.1724569329999999,-0.17504751,-11.95632267,-10.69564837,-7.831805557000001,-13.96516068,-9.76371904,-17.52527969,-7.3849042560000004,-3.630981347,-5.781976699829102,-10.656970977783203,-10.245723724365234,-9.42583179473877,-10.590557098388672 -930,930,L73A,-0.00747685,0.0013868620000000002,-0.0008390580000000001,0.023179191000000002,-0.064115567,-0.002177337,-0.0038499520000000002,-0.011103746999999999,0.030879958,0.018690144,-0.01591642,-0.0007174869999999999,-0.000960628,0.030107198999999998,0.016251182,-0.029505436,-0.098725698,1.100080585,2.476287868,-6.303990211,-5.55218396,-9.067375923,-5.373495941,-7.211072891000001,-4.315822342,-4.93892351,-1.47830732,-9.148443222045898,-9.504606246948242,-4.330544471740723,-5.755014896392822,-8.614550590515137 -931,931,L73C,0.015880851,0.009399786,0.069407413,0.08983670199999999,-0.724250974,0.08075977200000001,0.007424851999999999,0.024336849,0.020648324,-0.054199286,0.072998858,0.025935734,0.112879091,0.031590734,0.148082669,-0.548720807,-0.89978114,0.636938905,1.409077946,-9.659955618,-7.797995674,-11.35941367,-10.11229609,-9.99761972,-9.032452934,-7.381751486000001,-4.118376786000001,-11.68880558013916,-11.834534645080566,-8.700575828552246,-10.140925407409668,-12.314623832702637 -932,932,L73E,-0.032193585,-0.02060762,-0.45404262700000003,-1.793204936,-2.9475442689999998,0.03620599,-0.013067835,-0.051319334,-0.013497172,-0.064314694,0.023099454,-0.224795628,-0.683289625,-1.458274036,-2.128135836,-2.363855623,-3.531232914,1.42695384,0.820807066,-10.93263555,-9.551456619,-12.55317657,-10.83326192,-11.67215127,-10.05313135,-8.409953718999999,-6.817490654,-13.963175773620605,-14.551056861877441,-8.968749046325684,-11.619958877563477,-13.658768653869629 -933,933,L73D,-0.007161325,-0.037572552,-0.059480887999999996,-1.7524101669999999,-2.994795129,0.044371155999999995,0.019355712,-0.033678362,0.078371161,-0.041122399,-0.034022704,-0.08415726400000001,-0.034804512,-1.276981584,-2.227838749,-2.659684425,-3.3299058319999997,0.947747434,0.750002065,-12.32247162,-11.9773491,-13.23842351,-11.81318225,-13.01174426,-11.57165899,-9.327380676,-9.145311157,-14.377708435058594,-15.753459930419922,-9.764458656311035,-12.17694091796875,-14.556084632873535 -934,934,L73G,-0.022910036,0.003078483,0.00474493,0.015357063999999998,-1.4639466680000002,0.117438263,-0.007003873000000001,-0.038816197999999996,-0.013563792,0.024383346,-0.018226381,0.013659776,-0.004169916,0.021860716000000002,0.008853411,-1.365790123,-1.562103213,0.525396585,1.318414269,-10.33413128,-9.471213104,-12.52527628,-10.27609064,-11.18234621,-8.215730156000001,-6.109087167999999,-3.937370725,-12.68106460571289,-13.563140869140625,-7.543927192687988,-10.460674285888672,-13.181724548339844 -935,935,L73F,-0.051340172999999996,-0.038060907000000005,0.010240302,-0.053278238,-0.448223556,0.057962545,-0.047264886,-0.05541546,0.01857118,-0.044439449000000006,-0.031682364,0.04709539,-0.026614786,-0.089058179,-0.017498296,-0.320493345,-0.575953766,1.235423376,1.8019209090000001,-3.997847171,-3.114886307,-5.317045944,-4.878346878,-2.472757217,-4.206199509,-3.6846231680000003,-1.369137634,-8.472698211669922,-10.28477668762207,-7.077476501464844,-7.291734218597412,-8.293403625488281 -936,936,L73I,0.013393716000000002,-0.021910423999999998,0.005183018,-0.002772592,0.028685084,-0.011751602,0.015317943999999998,0.011469488,0.059829714000000006,-0.075457614,0.031636766000000004,-0.04460121400000001,0.05496725,-0.07473485099999999,0.069189668,-0.059166288,0.116536455,1.5187118819999998,2.566872107,-3.863398647,-3.359509262,-3.370143662,-4.023543053,-4.937362923,-3.626434334,-3.637685438,-2.366266146,-6.766679286956787,-9.249706268310547,-5.798127174377441,-6.731797218322754,-6.999451637268066 -937,937,L73H,-0.038784991,-0.054103331,-0.041802456,0.0051662,-1.5736759009999999,0.11313851,-0.00031465700000000003,-0.077255325,0.037660522,-0.022373672,-0.08583299,-0.084996899,0.0013919870000000001,0.011999215,-0.001666815,-1.480004994,-1.667346807,0.652300835,1.317587297,-8.057636627,-6.17494558,-8.629783652999999,-9.025859192,-6.544224167,-9.913370544,-5.798620596,-1.613499987,-13.685388565063477,-11.391810417175293,-7.752734661102295,-8.997035026550293,-12.142481803894043 -938,938,L73K,-0.010680711,-0.650762396,-1.682049234,-1.979532786,-2.943766498,0.021996302000000002,0.020655767,-0.042017188,-0.037517703,-0.562328953,-0.7391958390000001,-1.559326499,-1.8047719690000001,-2.074949559,-1.884116013,-2.883621133,-3.003911863,2.773865428,1.024208257,-10.90491996,-10.24283763,-11.93158435,-10.82577906,-10.87014426,-10.65425448,-9.309240749,-9.05312673,-14.690333366394043,-15.227035522460938,-11.333624839782715,-10.834220886230469,-15.363912582397461 -939,939,L73M,0.026361935,0.015778941,0.005162353,0.013937103000000001,-0.10406419,0.015761255,0.038722976,0.014000894,-0.028106126000000002,-0.003076427,0.034634307999999996,-0.01479723,0.025121935,0.001616667,0.026257537999999997,-0.108503365,-0.099625014,1.463557431,2.3832024069999997,-3.8949536030000003,-4.028867981,-4.46126902,-3.097025299,-4.819400283999999,-3.068205429,-3.674655188,-2.1659275190000002,-6.1850409507751465,-7.192242622375488,-3.846587657928467,-5.590157508850098,-6.274528503417969 -940,940,L73N,-0.012146497,0.016128115,-0.011162275,-0.45123873299999995,-2.274293433,0.082436202,0.005885708000000001,-0.030178701000000002,0.064841602,0.0076636690000000006,0.02459256,-0.007031764,-0.015292785,-0.271380456,-0.631097009,-2.017068137,-2.531518728,1.326564825,1.329883788,-11.57814435,-10.78497028,-12.560299,-11.80791635,-11.84512508,-10.89241103,-9.327380676,-9.14531113,-13.814414978027344,-13.557849884033203,-9.86837387084961,-10.68969440460205,-13.587960243225098 -941,941,L73Q,0.017952193999999998,0.050132984000000005,0.05372669099999999,-0.56246493,-1.5095346280000002,0.10094127,0.067236906,-0.031332518999999996,-0.029180005,0.088324625,0.011941343,0.042657294000000005,0.064796087,-0.21946228399999998,-0.9054675759999999,-1.496481189,-1.5225880669999998,1.22819738,1.379497999,-7.777840666,-8.062043747,-8.887946968,-6.881660103,-6.950113655,-8.107438858,-6.069517201,-4.620560756000001,-12.769854545593262,-9.987854957580566,-7.314868927001953,-8.433039665222168,-10.698585510253906 -942,942,L73P,0.004343286,-0.007240375,-0.000636882,0.022476496000000002,-0.13478089199999999,0.015944083,0.017822153,-0.009135582,0.033989984,0.0036044759999999997,-0.018085226,-0.00033171199999999996,-0.000942052,0.033765008,0.011187984,-0.093665329,-0.175896455,1.372413649,2.351118676,-3.107943782,-2.07627179,-6.2137012789999995,-1.419697609,-3.872377235,-1.9576709980000002,-3.12040644,0.35962014,-10.96832275390625,-6.369904041290283,-4.2662506103515625,-4.1389617919921875,-8.280001640319824 -943,943,L73S,0.000995064,0.001674422,0.046240690999999993,0.029119437,-0.986445615,0.09167470900000001,0.033719725,-0.031729598,0.001258126,0.0017033579999999999,0.001645485,0.041780648,0.050700733,0.037246265,0.020992609,-0.782957575,-1.189933655,0.630413013,1.369631712,-7.140405714,-6.049184677,-9.566310616,-7.06583152,-8.120005737,-4.900696022,-4.94164279,-2.414115749,-12.06056022644043,-9.25767993927002,-6.375872611999512,-7.499149322509766,-8.982620239257812 -944,944,L73R,-0.031299565,-1.411498419,-1.791456507,-1.7873332519999998,-2.580447035,0.079332082,-0.006559110999999999,-0.056040018,-0.065605944,-1.373785609,-1.449211228,-1.6248795059999999,-1.9580335080000002,-1.6763462880000002,-1.898320215,-2.12271821,-3.038175859,4.1975624410000005,2.137672549,-11.73544042,-12.92135189,-12.52713348,-10.42446619,-10.86356042,-11.94069012,-9.327380676,-9.145311135,-16.981525421142578,-13.982155799865723,-12.303934097290039,-10.617603302001953,-13.675296783447266 -945,945,L73T,-0.02059384,-0.02210319,-0.037882938,-0.003443189,-0.755295224,0.076290883,-0.012505761,-0.028681917999999997,0.04430232,0.012275161000000001,-0.05648154,-0.044886672999999995,-0.030879202,-0.036322396,0.029436017999999998,-0.589676411,-0.920914036,0.84076467,1.454027147,-8.12943324,-7.247911446,-10.16799795,-8.10525322,-9.482163506000001,-5.64384008,-6.498701822,-4.111969465,-10.619482040405273,-9.69833755493164,-5.940478324890137,-7.687692642211914,-9.421976089477539 -946,946,L73W,-0.083856435,-0.057215124000000006,-0.274073955,-1.775131512,-2.32208182,0.053937089,-0.058459827,-0.10925304300000001,-0.028436818,-0.044564804000000006,-0.069865443,-0.23640747,-0.311740439,-1.3695474719999998,-2.180715551,-2.3358269,-2.308336739,1.096195878,0.752934832,-8.195167238,-8.506304207000001,-8.69108477,-9.116256325,-6.167587715,-8.494603172,-6.258601733,-2.364015528,-12.722719192504883,-12.934247970581055,-8.851418495178223,-9.300665855407715,-11.518195152282715 -947,947,L73V,0.010649922,-0.000662605,0.01066079,0.017592247,-0.036333311,0.024543491,0.040681197,-0.019381354,0.10093677300000001,-0.001732438,0.00040722800000000004,0.035228802999999996,-0.013907224,-0.016892077,0.052076570999999995,-0.003946707,-0.068719915,1.338798161,2.641950211,-3.665205779,-3.541421997,-3.576102715,-3.155475105,-4.973662476,-3.0793666,-3.220299495,-2.029691838,-7.54714822769165,-9.30657958984375,-5.794801712036133,-6.579798698425293,-7.454136848449707 -948,948,L73Y,-0.022241227000000002,-0.010332269,-0.018572859,0.030946308,-1.7879032990000001,0.053528957,-0.010439844,-0.034042609,-0.078881971,-0.042480712999999996,0.021816176,-0.006537321,-0.030608397000000002,0.018559193,0.043333422,-1.49313493,-2.082671668,0.565240506,1.314980287,-7.51703033,-5.350079978999999,-9.510669144,-8.141713669,-5.900639427000001,-8.682049431,-5.260362777,-2.2053731180000002,-11.084692001342773,-12.264410018920898,-9.288269996643066,-8.737434387207031,-9.585105895996094 -949,949,L74A,-0.026083738999999998,0.029978357,0.000919232,0.013125423999999998,-1.314976379,0.090138337,-0.01440433,-0.037763147000000004,0.068370891,0.06778332599999999,-0.007826613,0.045364935999999995,-0.043526472000000004,0.049041384,-0.022790536,-1.087167017,-1.54278574,0.486114534,1.327736209,-3.693407797,-4.260184441,-3.815043137,-3.915535469,-2.08899865,-4.38727729,-3.0438684360000003,-0.151715725,0.4245128631591797,-2.471604347229004,-5.7825775146484375,-5.626645088195801,1.4309964179992676 -950,950,L74C,-0.046976283,0.000278301,0.048074755999999996,-0.26441253600000003,-2.220898794,0.061852820999999995,-0.015426833000000001,-0.078525733,0.040366661,0.008257166,-0.007700564,0.05752902,0.038620492,-0.126914694,-0.40191037799999996,-1.7447736919999999,-2.697023895,1.070334307,1.33552647,-10.43577897,-12.26280608,-10.29591154,-11.49155151,-8.510739334,-9.617886421,-7.390717887999999,-5.760507144,-5.8875555992126465,-8.05236530303955,-9.810519218444824,-9.710260391235352,-6.657373428344727 -951,951,L74E,-0.015613064,-0.037314174,-0.013733456000000002,-1.03588883,-2.636127763,0.116817184,0.010121467,-0.041347594,0.09048369199999999,-0.051749323,-0.022879023999999998,-0.034638888,0.007171976,-0.7322859540000001,-1.339491706,-2.587327256,-2.68492827,1.115791921,0.906526154,-11.51939574,-12.73613544,-10.84682243,-12.51947208,-11.00838402,-10.48616471,-6.964032763,-5.352190643999999,-6.329019546508789,-10.516746520996094,-9.9782075881958,-9.98224925994873,-6.992171287536621 -952,952,L74D,-0.07107390799999999,-1.2311976759999999,-1.610407898,-1.717094718,-2.735655563,0.060193665,-0.080213897,-0.061933918,-0.130051546,-1.28733037,-1.175064982,-1.8189292080000001,-1.4018865880000002,-1.94425147,-1.489937965,-2.56884385,-2.902467275,4.02536965,1.84501417,-13.86264142,-15.31346387,-13.81455099,-15.13405254,-11.86965215,-13.18148756,-9.359036782999999,-9.351993138,-7.417327880859375,-8.585561752319336,-10.168978691101074,-12.278005599975586,-7.134804725646973 -953,953,L74G,-0.012887098,0.02541357,-0.752166151,-1.7992008609999999,-2.386275324,0.09701302699999999,0.004027392,-0.029801587,-0.046239639000000006,0.060824659,-0.00999752,-0.525185283,-0.9791470179999999,-1.6709705990000001,-1.9274311219999998,-2.398225322,-2.374325326,1.8824083280000001,0.9262082709999999,-10.94658524,-13.51870602,-11.32702902,-11.08519626,-8.49701841,-10.30497649,-6.250203836,-4.114544375,-4.251465320587158,-8.101607322692871,-10.357022285461426,-9.4249849319458,-5.47047758102417 -954,954,L74F,-0.036409891,-1.238173072,-1.930240566,-2.450469263,-3.1124248860000003,0.107999068,0.01046337,-0.083283152,-0.032328139,-1.120579137,-1.355767006,-2.12929923,-1.731181901,-1.9993489869999999,-2.901589538,-3.0041526089999997,-3.220697163,0.45837037700000005,-0.680525515,-11.61816316,-12.54386303,-10.86236402,-12.64528864,-11.15732284,-10.88197727,-9.316485112,-9.055397934,-7.489885330200195,-9.254692077636719,-9.313188552856445,-10.103246688842773,-7.035898208618164 -955,955,L74I,0.00029283099999999996,0.05686352,0.034120258,0.033440691,-1.4735563680000001,0.007313961999999999,0.018889151,-0.018303489,0.092201011,0.064989998,0.048737042,0.061521413,0.006719103000000001,0.081132429,-0.014251047,-0.890846052,-2.056266684,0.554346207,1.3469012219999998,-4.407162672,-6.011362625,-3.0067218860000002,-4.443121979,-4.380247215,-4.194359657,-4.76524526,0.075602475,-3.5521793365478516,-7.512002468109131,-7.0050811767578125,-9.003191947937012,-4.7872748374938965 -956,956,L74H,-0.048783512,-1.050894421,-2.213600792,-2.387818916,-3.487305171,0.10008497400000001,0.033260722,-0.130827746,0.068013912,-0.98865428,-1.1131345609999999,-2.326433092,-2.1007684909999997,-2.3725741080000002,-2.403063724,-3.0763477339999996,-3.898262608,0.23620685600000002,-0.646385682,-15.06440324,-14.64071146,-15.18742181,-16.76523162,-13.73744101,-14.9912103,-9.359036782999999,-9.35199292,-9.456523895263672,-11.793686866760254,-9.990679740905762,-11.89254093170166,-8.869514465332031 -957,957,L74K,-0.052036885,-1.137728428,-1.8541715669999999,-2.182748103,-3.1061430989999996,0.081099724,-0.012510111,-0.091563659,0.13889974900000002,-1.1888439690000001,-1.086612886,-1.975715312,-1.732627821,-2.4989775830000003,-1.8665186230000002,-2.725629954,-3.4866562439999997,-0.145738786,-0.7301690359999999,-14.18143313,-15.03937639,-14.74704433,-14.73900453,-12.29664819,-14.08509222,-9.359036782999999,-9.351993018,-9.767675399780273,-12.152106285095215,-12.834245681762695,-13.09291934967041,-9.979694366455078 -958,958,L74M,0.03852772,0.018414876,0.039793984,0.019934201000000002,-0.428434117,0.019642165,0.059301875,0.017753565,-0.003559497,0.056668699,-0.019838947,0.006911754,0.072676213,0.031889457,0.007978944,-0.29105058,-0.565817653,1.3655839269999999,1.96527427,-6.142061215,-6.8755814289999995,-6.333085304,-5.72943277,-5.844398032999999,-5.92780854,-5.610253161,-3.6906643260000003,-4.970156669616699,-6.367023468017578,-7.8363447189331055,-7.708142280578613,-5.48411750793457 -959,959,L74N,-0.023085612000000002,-0.152651943,-1.3029033540000001,-1.67389584,-2.8724050119999998,0.05748067900000001,-0.001170295,-0.045000929,-0.013200379,-0.087779278,-0.21752460699999998,-1.488609836,-1.117196871,-2.011872107,-1.335919572,-2.539554474,-3.20525555,2.223362145,0.694219574,-12.30180972,-14.11656486,-12.02350327,-13.26573183,-10.66662369,-11.43662498,-6.922977781,-5.062897311,-6.924509525299072,-9.354604721069336,-10.576587677001953,-11.517382621765137,-7.928431510925293 -960,960,L74Q,-0.060332145,-0.082856653,-0.5989446310000001,-2.103866252,-3.24294313,0.152911997,0.006017429,-0.126681719,-0.009463001,-0.083989323,-0.081723983,-0.403022395,-0.794866867,-1.40340592,-2.804326583,-2.885330797,-3.600555463,1.707220454,0.927811872,-10.64060712,-11.64856188,-10.78763092,-11.64161214,-9.274302895,-9.85092775,-6.565824771,-2.7276514489999997,-7.161111831665039,-8.933248519897461,-8.157405853271484,-9.313867568969727,-7.319008827209473 -961,961,L74P,-0.015964399,-0.697350252,-1.830984295,-2.271607042,-2.872337698,0.108075012,0.010181735,-0.042110533,0.014847318,-0.553638824,-0.84106168,-1.9231416069999998,-1.738826982,-2.173402605,-2.369811479,-2.71881374,-3.0258616560000005,1.198603967,-0.153828521,-11.90106272,-13.22783706,-12.90607156,-11.97174718,-10.69229533,-10.70736244,-7.806955522000001,-6.066438327,-8.462152481079102,-10.5089111328125,-10.714439392089844,-10.159603118896484,-5.991575241088867 -962,962,L74S,-0.003771125,0.008548347,-0.34344615100000003,-1.66620322,-2.599628113,0.092326533,0.02112722,-0.02866947,0.048239239,0.020492923,-0.003396229,-0.277178272,-0.409714029,-1.5718374659999998,-1.760568973,-2.313399654,-2.885856572,1.3868352659999998,0.7854479440000001,-8.341780846,-9.697965408,-8.687616477999999,-8.763693794,-6.339389084,-8.220239464,-4.851743691,-3.4052423739999997,-3.2142720222473145,-5.340061664581299,-8.100748062133789,-7.947288513183594,-3.4630699157714844 -963,963,L74R,-0.026515805,-1.628701234,-2.015487388,-2.382380953,-3.126264978,0.070963716,0.003124173,-0.056155782,-0.17012128199999998,-1.698039301,-1.559363166,-2.092110275,-1.9388645009999999,-2.138251291,-2.626510615,-2.908971707,-3.343558248,0.032323347999999995,-1.100965185,-14.31317348,-14.69366666,-14.40202042,-15.49812894,-12.57450899,-14.39754237,-9.359036782999999,-9.351992997,-11.195858001708984,-12.153007507324219,-12.514419555664062,-13.220983505249023,-10.234614372253418 -964,964,L74T,-0.0032274029999999998,-0.004661313,0.006254917,0.021064031,-1.513027813,0.08937736800000001,0.006498025,-0.01295283,0.03212495,-0.015056663999999999,0.005734039,0.001354727,0.011155107,0.016138991000000002,0.025989071000000002,-1.5138231430000002,-1.512232482,0.8663418829999999,1.3367489959999999,-7.6569819720000005,-9.718582222,-7.500228951,-7.777633392,-6.69412999,-6.5943353039999995,-5.134492989,-3.1684561319999998,-3.29603910446167,-6.4631171226501465,-6.394649028778076,-7.784982204437256,-3.3675994873046875 -965,965,L74W,-0.024041267999999998,-1.503617449,-2.154350156,-2.179020532,-2.903445524,0.07156709900000001,-0.019014534,-0.029068001,-0.057690905,-1.57303208,-1.4342028169999999,-1.773637699,-2.535062612,-2.472991228,-1.885049835,-2.398613605,-3.4082774430000002,-0.6805542990000001,-1.101304165,-13.11447907,-13.5965399,-13.11915235,-14.031956699999999,-12.02631542,-12.79843099,-9.359036782999999,-9.351992994,-10.229724884033203,-12.604230880737305,-12.61689567565918,-12.75662612915039,-9.953747749328613 -966,966,L74V,0.0007499410000000001,0.028167892000000003,0.016143763000000002,0.03207235,-0.23273484,-0.006218969,0.010387123,-0.008887241,0.03538782,0.056391283,-5.550000000000001e-05,0.024151551,0.008135974,0.051911165999999995,0.012233533000000001,-0.186640429,-0.27882925,1.218678127,2.018171883,-3.903289162,-4.606488365,-3.1998925860000003,-3.62885775,-4.816596825,-3.264610283,-3.6769733610000004,-0.336897099,-2.5117979049682617,-6.547506332397461,-5.907011032104492,-8.330482482910156,-2.9046549797058105 -967,967,L74Y,0.010092519,-1.554455648,-1.841688992,-2.5119944469999997,-2.935389443,0.061216791,0.056889062000000004,-0.036704025,-0.062648251,-1.8210864690000002,-1.2878248270000001,-1.908987808,-1.774390175,-2.052038836,-2.971950057,-2.8807512,-2.9900276860000004,-0.198091538,-1.0927561000000001,-13.34446195,-13.75930566,-13.0528546,-14.15982388,-11.90029561,-13.85003001,-8.664891979,-6.830301298999999,-9.616621017456055,-11.320064544677734,-9.628731727600098,-11.959403038024902,-8.299803733825684 -968,968,C75A,0.046741127,0.053629460999999996,0.006241079,0.0057100269999999995,-0.124974444,0.034996118,0.030469565,0.06301268900000001,0.139065715,-0.012971875,0.120230796,-0.042896697000000004,0.055378854000000005,0.036787527,-0.025367472999999998,-0.151809544,-0.098139343,1.382163228,2.234419145,-6.021995252999999,-6.537822807,-6.683725204,-6.028494697999999,-5.886421173,-4.973512383,-4.945969968,1.879301736,-5.722037315368652,-2.1554183959960938,-4.8639326095581055,-4.632925987243652,-3.1295166015625 -969,969,C75E,-0.042069892000000005,-1.244999978,-1.889743288,-1.905157077,-2.657888088,0.10634143,-0.022570512999999997,-0.061569270999999995,0.137282569,-1.2037028490000001,-1.286297107,-1.7118000619999998,-2.067686514,-1.5438922519999998,-2.266421902,-1.8661115469999998,-3.449664629,4.0553235139999995,2.1709357540000003,-15.37273278,-16.4327984,-14.13451217,-18.20066129,-15.43410025,-12.66159178,-11.23350191,-7.992037776,-13.001805305480957,-12.63139533996582,-11.669119834899902,-13.321805000305176,-10.474003791809082 -970,970,C75D,0.002994453,-0.452667152,-1.54478751,-2.430277335,-2.621082525,0.103964689,0.010711497,-0.004722591,0.277161655,-0.355898185,-0.5494361179999999,-1.45691201,-1.63266301,-2.162130964,-2.6984237060000003,-2.037192227,-3.2049728230000003,3.8259844089999997,2.155372264,-16.14690484,-16.40199549,-16.58117992,-18.74674195,-16.38843601,-12.61617081,-11.23350191,-7.992037807999999,-11.69876480102539,-10.355854988098145,-9.887065887451172,-12.221111297607422,-9.562376022338867 -971,971,C75G,-0.009012161,0.050104729,-0.021442209,-0.008585221,-1.053258683,0.034990562,-0.012263773,-0.005760548000000001,0.12939405699999998,-0.007543584,0.107753042,-0.045917215,0.0030327970000000003,0.010505081999999999,-0.027675522999999997,-0.6541225420000001,-1.4523948230000001,1.245417445,1.628211047,-10.04001369,-10.08453535,-9.301021271,-10.29080714,-12.48466212,-8.039042563999999,-6.099015379,-1.0305117940000001,-9.090740203857422,-6.795005798339844,-8.414680480957031,-8.150335311889648,-7.1713666915893555 -972,972,C75F,-0.016512075,-1.544501752,-2.056827474,-2.148746198,-2.8395513880000003,0.085389886,-0.01170523,-0.021318919,0.00275414,-1.59655816,-1.492445344,-2.091291412,-2.022363535,-1.8556318180000002,-2.441860578,-2.508844332,-3.170258444,0.362554831,-0.9560033990000001,-11.81073969,-12.03612736,-9.764941817999999,-14.317552599999999,-13.13954972,-9.795526947,-7.994391099,-2.732038677,-10.901505470275879,-10.980294227600098,-11.85065746307373,-11.33508586883545,-9.548270225524902 -973,973,C75I,0.081882041,0.063593051,0.015331001,0.031988828,-0.9554388979999999,-0.019458535,0.081873882,0.0818902,0.060953173,0.009901489,0.11728461300000001,-0.010365296,0.041027298,0.042590543,0.021387112000000003,-0.600752753,-1.3101250420000001,0.7291329940000001,1.424116776,-13.22884645,-13.87663499,-11.1798395,-17.00764029,-14.02025236,-10.0598651,-7.755471947,-1.896905193,-8.771514892578125,-9.817570686340332,-10.291291236877441,-10.370867729187012,-6.505472183227539 -974,974,C75H,0.003912772,-1.3794876569999999,-1.9538415519999999,-2.181696159,-3.2950503689999997,0.130034062,0.020986862000000002,-0.013161319,-0.17733498,-1.497816966,-1.261158348,-1.8905207609999999,-2.0171623419999998,-2.1697709819999997,-2.193621335,-3.1697709819999997,-3.420329755,0.644613288,-0.900141399,-14.25985871,-16.48898833,-14.06549768,-14.329876800000001,-15.47977629,-10.93515446,-11.23350191,-7.992037793,-13.949005126953125,-14.07101821899414,-12.771915435791016,-13.425765991210938,-11.820930480957031 -975,975,C75K,0.002156791,-1.7150590890000001,-1.683259221,-1.9844127269999998,-3.147459253,0.134443809,0.016563908999999998,-0.012250327,0.127758999,-1.802923854,-1.627194324,-1.736989799,-1.629528642,-1.636028779,-2.332796675,-2.715210025,-3.5797084810000004,3.9937752110000004,1.6557936130000002,-15.55784837,-16.05559567,-14.87052335,-17.97863459,-15.98027707,-12.90421117,-11.23350191,-7.992037809,-14.085204124450684,-15.299057960510254,-15.588871002197266,-14.908353805541992,-13.50527572631836 -976,976,C75M,-0.032038209,0.055273305,-0.018830402,-0.31442765100000003,-1.655535905,0.12565421599999999,-0.037707487000000005,-0.026368931,0.003003806,0.011416625,0.099129984,-0.021691368,-0.015969436,-0.08459902400000001,-0.544256277,-1.77635638,-1.534715429,0.86187126,1.3156199659999999,-14.98349964,-15.080151,-11.95112576,-20.36936446,-14.99597459,-12.52088241,-7.630219326000001,0.41384154700000003,-10.253951072692871,-10.474239349365234,-10.957536697387695,-11.5116548538208,-8.834994316101074 -977,977,C75L,0.016727476,0.063849148,0.014088865,-1.091201824,-1.8691398909999999,0.060973045,0.02710089,0.006354060999999999,0.107230705,0.01812128,0.109577016,-0.007874999,0.036052729,-0.650956525,-1.5314471219999999,-1.884961893,-1.8533178890000002,1.9023422269999999,1.4756038219999998,-14.08618493,-15.04729922,-10.56240178,-20.47826015,-14.96135421,-9.381609261,-8.059922164,1.05815916,-9.149323463439941,-10.877176284790039,-10.0037260055542,-10.087105751037598,-7.701855182647705 -978,978,C75N,-0.01472233,-0.032952449,-1.252335921,-1.7171294369999999,-3.2335736330000002,0.1187934,0.007281482,-0.036726141000000004,0.175704015,0.00902519,-0.074930087,-1.2088876290000001,-1.295784213,-1.5033778169999998,-1.930881056,-2.950535848,-3.516611418,2.469540133,1.19706792,-14.056019199999998,-14.51755788,-14.74995905,-15.02417044,-14.9602105,-11.02819812,-8.837204836,-2.621569283,-11.779226303100586,-9.050687789916992,-9.931477546691895,-11.859245300292969,-9.720579147338867 -979,979,C75Q,0.0005599719999999999,-1.078237665,-1.740257823,-2.392133641,-3.0679572189999997,0.133072744,-0.005513237,0.00663318,0.074472628,-1.02052091,-1.1359544190000002,-1.847376886,-1.6331387590000002,-1.883589059,-2.900678222,-2.55259584,-3.583318597,3.206350552,1.170659143,-14.59543297,-14.65206615,-13.97835094,-17.88962863,-14.89940788,-11.55771124,-8.673551272000001,-3.019107175,-13.174129486083984,-13.68014907836914,-11.112828254699707,-14.022953033447266,-11.527371406555176 -980,980,C75P,-0.006089855999999999,-1.308213605,-2.087607773,-2.350018806,-2.9637010339999996,0.12799376699999998,0.0031021490000000002,-0.01528186,0.008079928,-1.359678203,-1.256749007,-2.21293937,-1.962276175,-2.292958529,-2.407079083,-2.7619618939999997,-3.165440173,0.03790081,-0.8291576159999999,-15.69223567,-15.90535382,-15.42069778,-17.9688344,-15.91687516,-13.24941718,-11.23350191,-7.992037759,-13.995688438415527,-12.257675170898438,-14.923778533935547,-11.758930206298828,-10.032547950744629 -981,981,C75S,0.013160894,0.051938005,-0.008555905,-0.023008404,-1.618066015,0.099583343,0.018974801,0.007346986,0.036206558,-0.033574772,0.137450782,-0.028859652000000003,0.011747843000000001,0.041303692,-0.08732050000000001,-1.6513899969999999,-1.5847420319999999,0.447381893,1.304622815,-8.195389909,-8.367662445,-8.270373199,-8.237214943,-9.456881699,-6.644817261,-6.359603077999999,-1.030224062,-7.812081336975098,-4.629802703857422,-5.986371994018555,-6.401205062866211,-5.93351411819458 -982,982,C75R,-0.010354531,-1.4101480990000002,-1.852716616,-1.9839925969999999,-2.91011735,0.134217501,-0.012279035,-0.008430027,-0.072560264,-1.5409473930000002,-1.279348804,-1.6487633819999998,-2.056669849,-1.839591701,-2.128393492,-2.942254043,-2.8779806569999997,3.648520262,1.3990449969999998,-15.72674646,-15.61574667,-15.15561286,-18.98158174,-15.87285349,-13.00793752,-11.20940465,-7.9349730229999995,-13.620198249816895,-14.423645973205566,-14.788710594177246,-13.347556114196777,-11.86184310913086 -983,983,C75T,-0.0014450770000000001,0.05576981599999999,-0.009663600999999999,0.01817083,-1.171416675,0.104844254,-0.010699139,0.0078089859999999995,0.040319068,0.020604023,0.090935609,-0.010773875,-0.008553326,0.08783506199999999,-0.051493402,-0.849231587,-1.493601763,0.6147110370000001,1.359127406,-10.06911689,-10.21140649,-10.41581057,-12.10150461,-8.560587173,-9.056275604,-7.139915716,-2.103690215,-7.597433567047119,-5.996783256530762,-7.254927158355713,-8.116872787475586,-5.647062301635742 -984,984,C75W,-0.011349745,-1.422312749,-1.636064596,-1.759551568,-2.412726065,0.116880579,-0.0034103640000000004,-0.019289126,-0.072115872,-1.35645951,-1.4881659880000002,-1.490097811,-1.78203138,-1.603016611,-1.916086525,-2.468318037,-2.357134093,4.041460235,2.0570221319999997,-15.65972502,-16.03973476,-13.98582176,-19.11966448,-16.32206633,-12.83133775,-11.23350191,-7.992037787,-12.969761848449707,-14.240621566772461,-15.335201263427734,-13.2161865234375,-12.288662910461426 -985,985,C75V,0.027750647000000003,0.044840223,-0.002847877,0.030028576,-0.262256631,0.046313754000000006,0.009275872,0.046225422,0.123543642,-0.019944771,0.109625217,-0.047027432,0.041331678999999996,0.046571937,0.013485215,-0.229096412,-0.295416849,1.133656501,1.842978875,-9.734516252,-10.000636300000002,-8.49402919,-13.68894885,-10.242230900000001,-6.246736015,-5.209353603,0.309955902,-6.4343767166137695,-6.603837966918945,-7.560453414916992,-7.971802711486816,-4.059355735778809 -986,986,C75Y,-0.01161151,-1.423035694,-2.098222631,-2.128243143,-2.982064465,0.108933845,0.005924393000000001,-0.029147412999999997,-0.095825071,-1.493940291,-1.352131096,-2.206157487,-1.990287775,-1.769404365,-2.48708192,-2.230135203,-3.7339937260000005,4.220120555,1.789117237,-13.13671996,-14.49208458,-11.170602,-14.55326479,-14.46130765,-11.00634081,-10.41093462,-5.502652412000001,-11.377403259277344,-11.650127410888672,-12.176477432250977,-11.787370681762695,-9.817658424377441 -987,987,G76A,-0.000738163,-0.001160087,-0.018194826,0.001006891,-0.006424416999999999,0.018457521,-0.029481987999999997,0.028005662999999997,-0.065810954,-0.021910584,0.01959041,-0.035236644,-0.001153007,-0.056300585,0.058314367,-0.008636806,-0.004212027,1.304413005,2.549351083,-1.200531851,-0.024408241,-1.85162513,-1.303297012,-1.359960396,-1.463368477,-2.099228852,1.087358853,-4.301322937011719,-3.942869186401367,-5.780701160430908,-5.06410026550293,-4.270841598510742 -988,988,G76C,-0.198757879,0.002186972,-0.034950044,-0.007290336,-1.115576811,0.071541575,0.034835408,-0.432351165,-0.08730112,0.007747121,-0.0033731779999999997,-0.012986836000000002,-0.056913252000000004,0.010538479,-0.025119151,-1.329702596,-0.901451025,0.7013155659999999,1.33133805,-9.87600731,-8.467379417,-10.86103766,-10.10920348,-8.510099426,-11.43231657,-7.132300718,-2.871840378,-9.364957809448242,-10.439153671264648,-10.409799575805664,-10.197686195373535,-10.204914093017578 -989,989,G76E,0.008772829000000001,-0.916709565,-2.03972138,-2.264288271,-3.0537558010000003,-0.058138796,-0.039724711,0.057270367999999995,0.228247592,-0.9332373759999999,-0.9001817540000001,-2.251976209,-1.82746655,-2.7883614239999996,-1.740215118,-2.974592315,-3.132919287,0.059159830999999996,-0.635101906,-11.07087691,-9.048050613,-11.99926998,-11.88263485,-9.3270019,-13.09742722,-9.05037166,-5.046374088,-11.6453218460083,-11.579121589660645,-11.508320808410645,-12.054130554199219,-11.62021255493164 -990,990,G76D,-0.028952877000000002,-1.01935933,-1.624557009,-1.8726232230000002,-2.3423340930000003,-0.001329793,-0.010277066,-0.047628687,-0.133725183,-0.887388145,-1.151330515,-1.617526534,-1.6315874830000001,-1.781525845,-1.963720601,-2.532028165,-2.15264002,4.170725486,2.274669865,-12.00406741,-9.90292691,-13.38555005,-12.335614300000001,-10.23137534,-14.16487047,-8.951541506,-4.53808911,-11.669068336486816,-11.409936904907227,-11.19503402709961,-11.528345108032227,-11.868806838989258 -991,991,G76F,-0.23407093199999998,-0.006641146999999999,-0.047276712,-0.503509116,-1.789810329,0.013959386,-0.052669605999999994,-0.415472257,0.007964035999999999,-0.033884149,0.020601856,-0.03339487,-0.061158554000000004,-0.34325366799999996,-0.663764563,-1.7233509059999998,-1.856269751,1.541912824,1.4087742769999998,-13.38580712,-9.913575202999999,-18.05843806,-13.84785667,-9.932236182999999,-15.176929500000002,-6.994403717999999,-3.0145902319999998,-13.49657917022705,-12.492452621459961,-13.686556816101074,-11.947272300720215,-12.034261703491211 -992,992,G76I,-0.10119651699999999,0.04816233599999999,-0.00374222,-0.18153645300000001,-1.8140708330000002,-0.013149393,0.00211033,-0.204503364,-0.018841866000000002,0.030061694,0.066262977,-0.006485805999999999,-0.000998633,-0.073479802,-0.289593104,-1.779046382,-1.8490952840000001,0.919501268,1.31834731,-12.07713985,-9.643192925,-17.36902167,-11.99789848,-8.201432404,-13.17415376,-5.730877222,-0.150529824,-11.990962028503418,-11.953167915344238,-12.541086196899414,-12.032578468322754,-12.771108627319336 -993,993,G76H,-0.134159257,-0.018706078,-1.313328212,-1.9076673240000002,-3.483680472,0.027627272,-0.032598102000000004,-0.23572041100000002,-0.115415485,-0.006670616999999999,-0.030741539,-1.210740224,-1.4159162,-1.988569745,-1.8267649030000002,-2.9877139919999998,-3.979646952,2.3801314540000003,0.9578654520000001,-12.87813787,-10.75860352,-14.54335578,-12.44305228,-10.47151653,-16.17416124,-9.045547994,-5.442607147,-13.89381217956543,-13.801933288574219,-12.809316635131836,-13.579547882080078,-13.862422943115234 -994,994,G76K,-0.113014976,-1.515354415,-2.5780437259999998,-2.536526207,-3.35351752,0.015415391,0.009617812,-0.235647763,-0.017333373,-1.615286692,-1.415422138,-2.786422804,-2.369664648,-2.845686764,-2.2273656490000002,-3.031917655,-3.6751173839999995,-0.61353004,-1.061962419,-13.21164809,-11.23691766,-14.24152084,-13.74595574,-11.0989102,-15.73493602,-10.62194635,-8.459220224,-14.15611457824707,-11.708601951599121,-14.666353225708008,-12.936676025390625,-14.987812995910645 -995,995,G76M,-0.111854985,-0.017873828,-0.072054776,-0.03370548,-1.799435365,0.005460085999999999,-0.017291178,-0.206418792,0.064522814,-0.017806983999999998,-0.017940672,-0.058796838,-0.085312714,-0.081806616,0.014395656000000001,-1.609013342,-1.9898573869999998,0.941426503,1.332580026,-10.1585078,-8.655023177999999,-12.81938037,-12.76938689,-5.755202675,-10.79354589,-6.925766167000001,-0.9423665609999999,-11.416877746582031,-8.106822967529297,-12.314994812011719,-11.543512344360352,-11.546500205993652 -996,996,G76L,-0.18781035,-0.010261449,-0.052465517,-0.267438362,-1.685606461,0.023415573999999998,-0.045727101,-0.329893598,0.048865083,-0.016494476,-0.004028422,-0.06234852,-0.042582514,-0.20654392,-0.328332803,-1.693156121,-1.6780568009999999,1.249992733,1.361508748,-12.21902982,-8.925948875,-15.86740022,-14.52306777,-7.54232045,-14.2364118,-7.04125587,0.141392842,-11.971259117126465,-11.287254333496094,-12.398859024047852,-10.709474563598633,-11.09265422821045 -997,997,G76N,-0.134887876,-0.61516894,-1.880766075,-2.173751946,-3.3637265419999998,0.096539001,-0.034271306,-0.235504445,0.034158271000000004,-0.469958948,-0.760378931,-2.0296276,-1.731904549,-1.912800302,-2.43470359,-2.877182442,-3.850270642,1.201050117,-0.14749067,-11.42889529,-10.39482754,-12.38905901,-11.5962772,-9.627952705,-13.13635999,-8.978125014,-4.971853758,-11.23755168914795,-10.896016120910645,-10.876978874206543,-11.572046279907227,-12.519021987915039 -998,998,G76Q,-0.161950913,-0.351404195,-1.60826415,-2.0440452209999997,-3.35474197,0.025706503999999998,-0.066368631,-0.257533195,0.038316126,-0.240816258,-0.46199213100000003,-1.469944317,-1.746583983,-1.927148286,-2.160942155,-3.016469163,-3.6930147769999997,2.695028868,1.096259539,-12.56167703,-10.26981557,-13.87873647,-13.74278053,-10.28445824,-14.63259434,-9.757290569,-6.103613039,-12.985330581665039,-12.689643859863281,-11.793877601623535,-12.310077667236328,-13.285056114196777 -999,999,G76P,-0.125741076,-1.242940786,-2.095809735,-2.371980644,-3.236796638,0.0435326,-0.024767721,-0.22671443100000002,-0.1206714,-1.205087431,-1.2807941409999999,-2.169230598,-2.022388872,-2.351211835,-2.392749453,-2.9054195110000003,-3.568173764,0.807129804,-0.6968215409999999,-12.63899756,-10.4596858,-14.55797478,-13.211150400000001,-11.13223648,-13.83394034,-10.62194635,-8.459220224,-13.432493209838867,-15.948103904724121,-12.690925598144531,-13.390016555786133,-13.125812530517578 -1000,1000,G76S,-0.148380241,0.0028768170000000003,-0.035051833,0.007652341,-0.032136065,0.021518844,0.0011806660000000001,-0.297941148,-0.018531835,-0.000828168,0.006581801,-0.027534699,-0.04256896599999999,-0.039597059,0.05490174,-0.048974101,-0.015298029,1.178277762,2.260932028,-5.318448616,-4.54477906,-5.963392128,-5.16715947,-4.59249707,-6.324415352000001,-4.508262633,-1.755396225,-6.433253765106201,-6.385254859924316,-7.659295082092285,-7.319289207458496,-7.145618915557861 -1001,1001,G76R,-0.13468666099999999,-1.573394212,-2.063019504,-2.2769917459999998,-3.250447668,0.047713788,-0.032776549,-0.23659677199999998,-0.14671691,-1.750179799,-1.396608624,-1.9793078569999998,-2.146731151,-2.369565037,-2.184418455,-3.400893967,-3.1000013689999997,-0.062491885,-1.110049036,-13.42546097,-10.79571595,-15.16512668,-14.63967319,-10.77531603,-15.75147298,-10.62194635,-8.459220224,-13.06092357635498,-12.80638313293457,-13.57310676574707,-12.243558883666992,-14.477429389953613 -1002,1002,G76T,-0.117080549,-0.008849978,-0.019513138,0.025075984,-1.521995719,0.040666997999999996,-0.023051415,-0.21110968300000002,-0.045944066,0.034077496,-0.051777452,-0.010705431000000001,-0.028320845,0.004474556,0.045677412,-1.3440593090000001,-1.6999321280000002,0.64031566,1.325629399,-8.247744933,-6.718817871000001,-10.2868671,-8.805021767000001,-6.865672493,-8.562345436000001,-6.459458242999999,-2.48513455,-8.705126762390137,-7.647279739379883,-9.066774368286133,-9.704108238220215,-8.816069602966309 -1003,1003,G76W,-0.207987571,0.017081838000000002,-0.035151501,-0.274966587,-1.716033837,0.048832404,-0.01063423,-0.40534091200000005,0.013977023,0.040872495,-0.00670882,-0.0008705389999999999,-0.069432462,-0.154467089,-0.395466084,-1.739280912,-1.692786761,1.097686333,1.336201203,-13.229323499999998,-10.44728798,-16.7906634,-14.16896783,-10.30122847,-14.43846983,-7.738709739,-3.211624431,-13.973114013671875,-14.572566986083984,-13.835729598999023,-12.686071395874023,-14.059074401855469 -1004,1004,G76V,-0.00396612,0.017771211999999998,-0.024386902000000002,-0.41734165799999995,-1.887239644,0.022038914,-0.017859548,0.009927309,-0.080552931,0.01111713,0.024425292999999997,-0.022574492999999998,-0.026199311,-0.281410809,-0.5532725070000001,-1.7178934030000002,-2.056585884,1.39720832,1.383527699,-10.13630155,-7.92838829,-15.16519548,-9.837261543,-6.605335571,-11.14532687,-7.315529146,-0.05330168,-9.324430465698242,-9.852243423461914,-10.763071060180664,-10.981306076049805,-10.548982620239258 -1005,1005,G76Y,-0.275535708,-0.007914146,-0.05184862,-0.603999159,-1.7525129000000002,-0.023435333,-0.124975431,-0.426095984,-0.041165982000000004,0.011095553000000001,-0.026923845,-0.012229861000000002,-0.091467378,-0.429509287,-0.77848903,-1.735854781,-1.769171019,1.631429035,1.433211156,-13.36634782,-10.45146325,-17.81374196,-12.80981652,-9.81697261,-15.93974477,-7.690368363999999,-2.654338128,-14.16824722290039,-13.673598289489746,-13.655755996704102,-13.018412590026855,-12.642898559570312 -1006,1006,A77C,0.037604814,0.015472763999999998,0.004788188,-0.00573169,0.031666339,0.021386352999999997,-0.015816748999999998,0.09102637699999999,-0.22702135199999998,0.003102691,0.027842837000000002,-0.059651797,0.069228172,-0.046057235999999994,0.034593857,-0.00269428,0.066026958,1.163389478,2.4501491090000003,-6.687918579,-6.873618767000001,-8.53809726,-6.583049622000001,-6.898452515,-4.546374733,-4.518973297,-3.728902113,-8.993194580078125,-8.798556327819824,-9.656179428100586,-8.721153259277344,-8.729458808898926 -1007,1007,A77E,-0.020805263,0.022256052999999998,0.037595676,-0.011047973,-1.10575645,0.033872913,-0.030346953,-0.011263573,-0.20515938,0.109127125,-0.06461502,-0.00209269,0.077284041,-0.036537167999999995,0.014441223000000001,-0.882304339,-1.329208561,0.802578173,1.386337547,-6.872925688,-5.528636932,-6.50172403,-9.387667191,-6.239468391,-6.707131897000001,-4.947344413,-1.374890572,-9.406753540039062,-6.227023124694824,-9.995349884033203,-9.907817840576172,-9.447929382324219 -1008,1008,A77D,0.036566997999999996,-0.025913877000000002,0.044084167,0.016677015,-1.23474708,0.031479705,0.02119271,0.051941285,-0.237047685,-0.009449233000000001,-0.04237852,-0.028319379,0.116487712,-0.041325651,0.07467968,-0.803485109,-1.6660090509999999,1.208150076,1.523293688,-8.96999187,-7.984231643999999,-9.527714096,-10.84476405,-7.640491097000001,-8.852758469,-6.157526356,-5.308886177,-12.3464994430542,-8.913618087768555,-11.888671875,-11.350371360778809,-12.556191444396973 -1009,1009,A77G,0.035843381,-0.015141845,0.002624282,-0.004488878,-1.1522916859999999,0.059663814,-0.014576562,0.086263323,-0.259007922,-0.006651539000000001,-0.02363215,-0.062502086,0.06775065,-0.061004575,0.052026819,-0.889494518,-1.415088854,0.958543602,1.418953336,-5.123640797,-4.924544571,-5.048627831,-5.914195175,-5.45094133,-4.279895081,-3.806464828,-2.882959615,-7.251662254333496,-7.608262538909912,-5.277714729309082,-8.126934051513672,-9.803647994995117 -1010,1010,A77F,0.057450019000000005,-0.048037249000000004,-0.032784544,-0.039051586,-0.047762399000000004,-0.036731018,-0.008953301,0.12385333800000001,-0.407485327,-0.071891513,-0.024182985,-0.065785487,0.000216399,-0.140964595,0.062861424,-0.105126731,0.009601933,1.402876335,2.227808267,-9.728875562999999,-9.167750801,-12.35118193,-10.84643547,-9.122790862999999,-7.15621875,-4.1253721269999994,-3.792054397,-8.855463027954102,-5.549263954162598,-10.14647102355957,-10.70494556427002,-8.796873092651367 -1011,1011,A77I,0.006484655,-0.014691527,-0.008791756999999999,0.021222737999999998,-0.447714455,0.00247353,-0.030787515,0.04375682400000001,-0.28745718800000003,0.058541580999999995,-0.087924635,-0.015839211000000002,-0.001744302,0.005720866999999999,0.036724608,-0.289412826,-0.606016083,0.938011716,1.6661695230000002,-8.236519081,-6.450390082999999,-9.371478874,-10.40665878,-7.827270942999999,-7.126796722000001,-5.125156489,-4.15581182,-7.987643241882324,-10.345494270324707,-11.076318740844727,-9.799100875854492,-8.457200050354004 -1012,1012,A77H,0.071173928,-0.007256348,-0.000492809,0.014397303,-0.045084475,-0.014020655,0.056911065999999996,0.08543679,-0.209614293,-0.035441554,0.020928858999999998,-0.10610284800000001,0.10511723,-0.08401565,0.112810256,-0.056471405,-0.033697545,1.431794363,2.4714841080000003,-8.047659973,-6.917164146,-11.26828677,-8.624624062,-5.843152016,-7.585072867999999,-4.435187592,-4.108565032,-8.685914039611816,-7.7833571434021,-10.165732383728027,-10.346244812011719,-10.395630836486816 -1013,1013,A77K,0.049965434,-0.050122967000000004,-0.0031809720000000002,-0.013919141999999999,-0.10161699699999999,0.008047406,0.030146283,0.06978458400000001,-0.27733533,-0.08890851599999999,-0.011337416999999999,-0.07764713200000001,0.071285189,-0.12933952099999999,0.10150123800000001,-0.11585035699999999,-0.087383636,1.36111989,2.194949085,-6.539634907999999,-4.241741005,-7.739748337000001,-8.565202744,-5.930411247,-6.221071205,-3.98182045,-3.451015588,-10.912677764892578,-8.580666542053223,-11.389825820922852,-11.132463455200195,-9.917745590209961 -1014,1014,A77M,0.013687251000000001,0.00436159,0.031667438,0.024997295,0.00367316,-0.03223846,-0.026222898999999997,0.0535974,-0.18535465899999998,0.11562127,-0.106898091,0.015345945,0.047988931,0.016981068000000002,0.033013522000000003,0.055367673,-0.048021352999999996,1.242435059,2.981332762,-7.167273814,-4.589065338,-8.378811325,-9.604229355,-6.893565315,-6.370697739,-5.0985153,-3.8020842989999997,-6.851665019989014,-6.996697902679443,-9.225642204284668,-9.618078231811523,-7.43321418762207 -1015,1015,A77L,0.031469627,-0.017614538,0.016396292,-0.003183666,-0.05205512,-0.051001332,0.009771245,0.053168007999999996,-0.183521963,-0.016131936,-0.01909714,-0.055406156,0.088198739,-0.048412352,0.042045020999999995,-0.07832668799999999,-0.025783552,1.320269367,2.2901041419999997,-6.9304190839999995,-4.667390900000001,-8.719584595,-8.201834305,-6.861184631,-6.20210099,-3.234713777,-2.70753155,-6.67061185836792,-6.98738956451416,-9.581184387207031,-9.066620826721191,-7.21189022064209 -1016,1016,A77N,0.030823456000000003,-0.04101871,0.015666112,-0.014621358999999999,-0.102364519,-0.022762532000000002,0.027109297,0.034537614,-0.21387982,-0.056366389,-0.025671031,-0.045303428,0.076635652,-0.017127761000000002,-0.012114956000000001,-0.124007669,-0.080721368,1.203668451,2.104324851,-7.608313084,-7.327210547999999,-9.30059819,-8.129589935,-5.8258091510000005,-7.458357597000001,-4.79708571,-4.378504849,-10.588481903076172,-8.74111270904541,-11.460481643676758,-10.372584342956543,-10.858139038085938 -1017,1017,A77Q,0.006138258000000001,-0.058917172000000004,-0.029064326,-0.052379304,-0.053635759000000005,-0.031816009,0.004151226,0.008125289,-0.241261791,-0.044126279000000004,-0.073708065,-0.10435439999999999,0.046225748,-0.08536679400000001,-0.019391814,-0.102259575,-0.005011942,1.304313342,2.205744571,-6.975806459,-4.619848129,-7.561933342000001,-8.821864417999999,-6.462393745,-7.4129926610000005,-4.803229085,-3.246582107,-9.231585502624512,-7.2108964920043945,-9.18502426147461,-10.063817024230957,-9.538741111755371 -1018,1018,A77P,0.0041314509999999995,-0.284897205,-1.557641204,-2.1699076440000002,-2.5264617,0.00471968,0.010424912,-0.00216201,-0.108881659,-0.164171972,-0.405622438,-1.593847281,-1.521435127,-1.9828172480000001,-2.35699804,-2.181949811,-2.870973588,3.766617301,2.09751268,-10.65186323,-9.572050697,-11.42293325,-11.79851699,-10.08500626,-10.38080894,-8.705427632000001,-9.614531994,-13.927189826965332,-14.441202163696289,-12.913468360900879,-12.490632057189941,-13.295089721679688 -1019,1019,A77S,0.035106804,0.013368553,0.03985466,0.016302597,-0.106346494,0.011849931000000001,-0.012605698,0.082819306,-0.241940513,0.031791303,-0.005054197,-0.01579498,0.095504299,0.000641256,0.031963938,-0.07266742799999999,-0.14002556,1.181659527,2.2376350080000003,-5.185596034,-5.086449554,-5.699865585,-5.931232627999999,-4.6501632310000005,-4.560269173,-3.635938546,-3.443494686,-7.453767776489258,-6.855410575866699,-7.016479015350342,-7.161948204040527,-7.921922206878662 -1020,1020,A77R,0.025660961,-0.021739187000000004,-0.007012498000000001,-0.018575674,-0.388606684,0.019988571,0.010319694,0.041002227999999995,-0.210810145,-0.014066538,-0.029411836,-0.078259663,0.064234668,-0.08577065800000001,0.048619311,-0.307798274,-0.46941509299999995,1.753896115,2.2199075930000003,-8.118550456,-5.531459717000001,-10.818280699999999,-10.05234763,-6.265542084,-7.925122153999999,-4.443004864,-3.4011665580000003,-10.67896842956543,-8.814273834228516,-11.41780948638916,-11.39508056640625,-10.88361930847168 -1021,1021,A77T,0.009135381,-0.011429865,0.00021455,-0.038796865,-0.233979562,0.068669667,0.003588596,0.014682165,-0.204119983,0.038977861,-0.06183759,-0.037889701,0.03831880000000001,-0.07170419,-0.005889539,-0.177013485,-0.290945638,1.419586028,2.150478767,-4.972706778,-3.4807188489999996,-4.79836515,-6.730765915,-4.34101107,-5.512672905,-4.687920605,-1.884930054,-6.878259658813477,-8.22197151184082,-8.105525970458984,-7.243648529052734,-6.093612194061279 -1022,1022,A77W,-0.010037885,-0.022470443,0.006612425,-0.025782612000000003,-1.6479342469999998,0.050072347999999996,-0.00012971600000000002,-0.019946053999999998,-0.241284109,0.028475421,-0.073416306,-0.056452132,0.069676982,-0.070629683,0.019064459,-1.5733002059999999,-1.7225682869999999,0.63772385,1.31531363,-11.41652313,-10.15662836,-13.12126321,-12.40772763,-10.63035065,-10.76664582,-5.9277859920000004,-5.807111517999999,-9.422306060791016,-9.399441719055176,-12.492620468139648,-12.665373802185059,-11.871306419372559 -1023,1023,A77V,0.006094166999999999,-0.003418942,0.011197465,-0.005472483,-0.046064699,-0.034080658,-0.029416143999999998,0.041604478,-0.242265053,0.011493496,-0.018331379,-0.031502744,0.053897673,-0.038540103,0.027595137999999998,-0.058241832,-0.033887565,1.358902165,2.418300926,-5.388092123,-4.095331833,-5.560470581000001,-7.212319648999999,-5.335764526,-4.736574028,-3.448575308,-2.7049541219999997,-6.871382236480713,-8.966540336608887,-9.499351501464844,-8.158967971801758,-6.654440402984619 -1024,1024,A77Y,-0.001738225,0.008319888000000001,-0.003515975,0.00039913,-0.015251162,-0.045957843,-0.058565023,0.055088572999999995,-0.258101795,0.057562292,-0.040922517,-0.021157086000000002,0.014125136000000002,0.012656703,-0.011858443,0.041536724,-0.072039047,1.190884922,2.819835845,-10.13204072,-8.911687645,-13.10412857,-11.08639387,-8.902134605,-8.655858894,-5.125928953,-3.5374393580000003,-8.84257984161377,-6.439080238342285,-9.880207061767578,-10.540757179260254,-9.754606246948242 -1025,1025,V78A,-0.027555502000000003,0.028317385,-0.03081787,-0.027847157999999997,-1.656196595,0.054383624000000005,0.004113835,-0.059224837999999995,-0.004426986,0.034597035,0.022037735,-0.020579704,-0.041056035,-0.008189373,-0.047504942,-1.4305480259999999,-1.8818451630000002,0.857223423,1.337815564,-4.062076318,-4.202271973,-3.100818359,-5.820414177000001,-3.4625128860000003,-3.724364197,-3.7119873080000003,-1.333522514,-7.309543132781982,-8.628171920776367,-8.412317276000977,-8.71063232421875,-8.877241134643555 -1026,1026,V78C,0.026739392,0.036746746000000004,0.019432161,-0.18533655100000002,-1.68324771,0.09669272400000001,0.033276344,0.020202439,-0.009745623,0.08511134,-0.011617849,0.007092815,0.031771507000000004,-0.08811702800000001,-0.282556074,-1.5363938209999999,-1.8301015980000002,0.793518574,1.3246090940000002,-8.693039894,-7.206258438,-6.377994087,-12.60800379,-9.155328796000001,-8.117614357,-5.841966481,-4.404980384,-10.56373119354248,-11.846353530883789,-12.586716651916504,-12.02180004119873,-12.884942054748535 -1027,1027,V78E,0.057113482,0.036711092,-0.10133983199999999,-1.556595863,-2.698340925,0.025070162000000003,0.064694858,0.049532106,0.009347684,0.034849078,0.038573105,-0.056752440999999994,-0.145927223,-1.496376054,-1.616815671,-2.603828308,-2.7928535410000004,0.778186905,0.710328044,-10.532427900000002,-10.24104378,-8.616250893,-13.796377,-9.903016609,-10.10545122,-8.519744082,-7.302159776,-14.323600769042969,-11.864306449890137,-15.79698371887207,-14.164773941040039,-13.735479354858398 -1028,1028,V78D,0.020108278,-0.539073526,-1.898579971,-2.677275235,-2.787729305,0.011166081000000001,0.043481415,-0.00326486,0.08870515,-0.27724747,-0.800899582,-1.474267269,-2.322892672,-2.42700979,-2.927540679,-2.493069359,-3.08238925,1.242355429,0.108476669,-11.68439271,-11.5038268,-9.476012062,-15.49437652,-11.130044300000002,-10.81770385,-9.404967002000001,-9.769835496,-17.234811782836914,-14.50589370727539,-17.489580154418945,-16.286521911621094,-14.985837936401367 -1029,1029,V78G,-0.027763323,-0.046947496,-1.31711,-2.105566334,-3.18578003,0.083098031,-0.004739427,-0.050787217999999995,0.02351664,0.010964568999999999,-0.10485956,-1.2233401590000001,-1.4108798409999999,-2.1180907330000003,-2.093041934,-3.1383928119999998,-3.233167248,0.8910931559999999,0.11161704199999999,-9.755791618,-9.511101875,-7.396039032000001,-13.43148764,-9.277208099,-9.163121445,-6.645698291,-3.9181378760000003,-12.893416404724121,-13.582985877990723,-14.369178771972656,-13.893101692199707,-14.271389961242676 -1030,1030,V78F,-0.025469275,-0.022839962999999998,-0.050249756,-0.880751637,-2.180567854,0.019111483999999998,-0.029308288,-0.021630261,0.072448266,0.013446943000000001,-0.059126869000000006,-0.065957977,-0.034541535,-0.476853914,-1.28464936,-1.9298581069999998,-2.4312776,1.503619779,1.345472145,-8.935931407,-7.664467865,-6.0858837889999995,-13.64936545,-10.99159146,-6.288348472999999,-5.128154225,-1.7804540819999999,-8.630292892456055,-11.060009002685547,-11.879698753356934,-10.284453392028809,-10.960519790649414 -1031,1031,V78I,-0.062067489,0.016499933,0.051312049000000005,-0.003313895,0.00016968400000000002,-0.012927375,-0.100050322,-0.024084655,-0.10381161800000001,0.097941599,-0.064941734,0.109716569,-0.007092472,0.069588418,-0.076216208,0.10772554,-0.10738617199999999,1.080855097,3.0984630010000003,-1.321723781,-1.0785215,-0.861712845,-1.9342504580000002,-1.704240578,-1.029893524,-2.40347452,-1.458571152,-4.26448917388916,-4.619683265686035,-4.84987735748291,-4.669462203979492,-4.8023362159729 -1032,1032,V78H,-0.016270898,0.010942452,0.028227537,-1.395238734,-2.543009613,0.028662818,0.00107947,-0.033621265,0.01578637,0.126303282,-0.104418378,0.09684216,-0.040387086,-1.133449261,-1.657028207,-2.177232435,-2.9087867910000003,0.916804627,0.76543097,-13.10812769,-11.4709725,-10.43869939,-18.63355664,-13.11593847,-11.88147144,-9.404967002000001,-9.769835496,-13.966581344604492,-15.4041166305542,-17.096385955810547,-15.876161575317383,-15.468924522399902 -1033,1033,V78K,0.0018391179999999998,-0.040107999,-1.266341998,-1.86552629,-2.59120482,0.035098778,0.042531337,-0.038853101,0.066450097,0.034246193,-0.11446219,-1.242360167,-1.290323828,-1.9204016309999998,-1.810650949,-2.287491195,-2.894918445,3.081158498,1.624375066,-11.34127313,-10.80767766,-8.72908091,-14.58131466,-10.94871952,-11.63957289,-9.404967002000001,-9.769835496,-14.861059188842773,-14.225685119628906,-18.850032806396484,-16.026535034179688,-16.27814292907715 -1034,1034,V78M,-0.061921223,0.0024918,-0.035672751,-0.051007132999999996,-0.582851742,-0.044427402000000005,-0.074949591,-0.048892855,0.02369312,0.063219975,-0.058236376,-0.00238476,-0.068960742,-0.029490996000000002,-0.072523269,-0.388598315,-0.777105168,1.325946355,1.813477872,-5.577692776,-3.782774368,-3.86007341,-8.493511444,-5.767599442000001,-5.984505219,-4.561860221,-2.828694156,-7.297290802001953,-7.77833366394043,-9.82862663269043,-8.248104095458984,-8.117849349975586 -1035,1035,V78L,0.010158283,0.039151264,-0.014894886999999999,-0.010168567,-0.34449891,-0.017061268,0.015847088,0.004469477,0.03760816,0.056109612,0.022192916,-0.005619712,-0.024170061,-0.00663738,-0.013699753,-0.244243085,-0.444754735,1.120110615,1.819710138,-3.771456212,-2.371703178,-1.886697784,-6.049359871,-4.538904533,-4.010615692,-2.25114419,-0.698352594,-5.490485668182373,-5.7583088874816895,-6.895547866821289,-5.880324840545654,-6.438656330108643 -1036,1036,V78N,0.109613889,0.10699724099999999,-0.7763474779999999,-2.041028381,-2.753542442,0.11098701,0.134712585,0.08451519199999999,0.037409082999999996,0.081191342,0.13280314,-0.719264977,-0.833429979,-1.519040039,-2.563016722,-2.488189594,-3.0188952889999996,2.245832708,1.1785706470000001,-10.83381969,-9.959333588,-9.126215126,-14.98013526,-10.47648077,-9.626933722999999,-8.570608566,-7.304091845,-13.779542922973633,-13.895286560058594,-16.369792938232422,-14.945009231567383,-14.570618629455566 -1037,1037,V78Q,-0.004544015,0.06450285900000001,-0.090802632,-1.611977588,-2.523461653,0.087838506,0.034859493,-0.043947522999999995,-0.051435077,0.099517596,0.029488121000000003,-0.088363842,-0.09324142199999999,-1.4787908790000002,-1.745164296,-2.146910439,-2.900012867,2.444705609,1.527175785,-11.20310578,-10.55054248,-9.018334068,-14.27371986,-10.66071827,-11.51221422,-9.404967002000001,-9.769835496,-13.221118927001953,-12.636175155639648,-15.570417404174805,-13.981261253356934,-14.134730339050293 -1038,1038,V78P,0.007812375999999999,-1.3839294180000001,-2.338744619,-2.553140845,-3.162109295,0.041470082000000005,0.013359995,0.002264756,-0.051943431,-1.420364231,-1.347494605,-2.255159574,-2.4223296640000003,-2.202149766,-2.904131923,-2.944902945,-3.379315645,0.164255557,-0.9114215509999999,-11.28568029,-10.96703996,-9.456898597999999,-14.24493577,-11.223206300000001,-10.53632084,-9.18009789,-8.885780033,-14.345537185668945,-15.56757926940918,-15.344616889953613,-14.20670223236084,-15.409753799438477 -1039,1039,V78S,5.6999999999999996e-05,-0.01492458,-0.029728687,-1.5818225069999998,-2.7418226160000003,0.05588670900000001,0.032656862,-0.032542877000000005,0.060577734,0.000567411,-0.03041657,-0.049098695,-0.010358678,-1.451837586,-1.7118074269999999,-2.5459258780000003,-2.937719354,0.802916582,0.7161327359999999,-8.805281395,-8.415005096,-7.566246788,-12.84734567,-8.017875366,-7.179934059,-7.159195795,-5.310112065,-11.402904510498047,-12.306654930114746,-12.753140449523926,-13.028829574584961,-13.10270881652832 -1040,1040,V78R,-0.016696638,-0.8817764659999999,-2.15087015,-2.720000761,-3.102488852,0.07550873599999999,0.013823101,-0.047216376,-0.026863254,-0.781738697,-0.981814234,-2.0781431280000002,-2.223597172,-2.18578761,-3.2542139110000003,-2.4948852269999997,-3.710092477,1.163432303,-0.380500606,-11.77599404,-11.200096,-9.295713226,-14.83683981,-11.28011063,-12.26721054,-9.404967002000001,-9.769835496,-13.226297378540039,-15.363715171813965,-18.646041870117188,-16.771984100341797,-16.756244659423828 -1041,1041,V78T,-0.047361462,-0.013638888,-0.036233974,-0.017847592,-1.133446022,0.085036623,-0.019340307,-0.075382617,-0.025164889,0.06496667099999999,-0.092244446,-0.010690881000000001,-0.061777067000000005,0.016883013,-0.052578195999999994,-0.8273278059999999,-1.4395642380000002,0.6926381220000001,1.3730777790000002,-4.782004752,-4.64653241,-3.81305806,-6.092572174,-4.074017715,-5.283843398999999,-4.947254074,-2.4570170669999998,-7.9507365226745605,-7.965014934539795,-8.515310287475586,-9.986623764038086,-8.425522804260254 -1042,1042,V78W,-0.015194464,-0.006698435,-0.188115187,-1.626287272,-3.018125613,0.016416326000000002,-0.007709725,-0.022679202000000002,-0.007536352,0.000493439,-0.013890308999999998,-0.185521987,-0.190708386,-1.543628536,-1.708946007,-3.072086102,-2.964165123,1.068385064,0.7331822790000001,-10.98333531,-9.522569191,-8.576773697,-14.5115048,-12.81020496,-9.495623878,-7.5532061310000005,-5.550567107000001,-12.594185829162598,-14.323180198669434,-15.632065773010254,-14.429208755493164,-15.875898361206055 -1043,1043,V78Y,-0.011703516,-0.001238355,-0.140580622,-1.732783391,-3.0241013789999998,-0.005414191,0.032659972999999995,-0.056067004000000004,0.055128393,-0.008961695,0.006484985,-0.17904832,-0.10211292300000001,-1.48081484,-1.984751942,-2.908602245,-3.139600513,1.1831139529999999,0.760283116,-10.58229114,-9.315712074,-7.937860328999999,-15.48936933,-12.09290049,-8.075613487,-6.379704826,-3.329321517,-10.972204208374023,-13.44339370727539,-14.014710426330566,-13.3478422164917,-13.49836254119873 -1044,1044,L79A,-0.027199496,0.020965509,-0.00032943699999999997,-1.4004483230000002,-2.179578454,0.052610227999999995,-0.025240415,-0.029158577,-0.140901066,0.026562281,0.015368737,3.84e-05,-0.0006972739999999999,-1.18187343,-1.619023216,-2.117712719,-2.241444188,0.7793568679999999,0.735947185,-11.44791021,-11.79618906,-8.965540764,-10.03492208,-11.18583176,-15.25706737,-7.4516374679999995,-2.8302191889999997,-12.24049186706543,-10.1224946975708,-12.668122291564941,-12.485065460205078,-14.815543174743652 -1045,1045,L79C,-0.052613768,0.020461453,0.02222396,-1.3800633080000002,-2.26771596,0.091646041,-0.020622069,-0.08460546599999999,0.118005724,0.017321625,0.02360128,0.038542863,0.005905056999999999,-1.068190641,-1.691935975,-2.109224609,-2.42620731,2.142608125,1.463108565,-11.53625072,-9.723113419,-10.25314166,-11.93094589,-12.21417496,-13.55987766,-7.5166219110000005,-3.5646175189999996,-12.867178916931152,-12.845390319824219,-14.982711791992188,-12.883681297302246,-15.74599838256836 -1046,1046,L79E,-0.024628399,0.002605446,-0.999195278,-1.8881364880000002,-3.1290289419999997,0.021471003,-0.021610083999999998,-0.027646713,0.144334663,0.03382983,-0.028618937999999997,-0.933556718,-1.064833838,-1.7669701230000001,-2.0093028530000003,-2.8277481489999996,-3.430309735,2.2508329590000002,1.037657499,-13.09266496,-11.97408675,-11.3318261,-12.04619616,-13.45608823,-16.65512756,-8.190376404,-5.159379883,-17.48850440979004,-14.00023365020752,-17.98345947265625,-16.851118087768555,-18.608156204223633 -1047,1047,L79D,-0.01514938,-1.096653208,-1.993373786,-3.157187585,-3.0608791319999997,0.026019672999999997,-0.015715118,-0.014583641000000001,0.17236338699999998,-1.074835993,-1.1184704220000001,-2.023147651,-1.96359992,-2.90002675,-3.414348419,-2.529441012,-3.592317252,0.054865335,-0.6803795659999999,-16.64588079,-16.71652667,-15.288191199999998,-15.60343378,-16.19079913,-19.43045316,-10.88598105,-10.08874765,-19.35984992980957,-16.46059799194336,-19.546907424926758,-17.55228614807129,-20.33956527709961 -1048,1048,L79G,-0.028099122999999997,-0.019732318999999998,-1.070240267,-2.059000909,-2.957194765,0.054761721,-0.012649117,-0.043549128,0.03239566,-0.000253641,-0.039210997000000004,-1.023416898,-1.117063636,-1.785576425,-2.3324253930000003,-2.591081946,-3.323307583,2.462287334,1.159028495,-14.18183921,-13.76888288,-11.84847445,-13.88775539,-14.25061777,-17.15346558,-8.597913307999999,-5.714715274,-13.63442611694336,-14.214430809020996,-16.9898681640625,-15.945308685302734,-16.899023056030273 -1049,1049,L79F,-0.01025245,0.012232916000000002,-0.029724262999999997,-1.093196663,-1.8680204669999998,0.033997307000000004,0.008388181,-0.028893081,0.037664813,0.010527574,0.013938256999999999,-0.044932282000000004,-0.014516244,-0.8313834959999999,-1.355009829,-1.7160702630000002,-2.019970671,2.504333843,1.9005230430000002,-8.465023422,-10.94694992,-6.956252144,-7.58403598,-8.726030571,-8.111848495,-6.441491471,-1.5360712909999998,-9.260910987854004,-9.039942741394043,-9.685598373413086,-8.982547760009766,-10.5543212890625 -1050,1050,L79I,-0.07409731,0.005641340999999999,-0.032207669,-0.280652553,-1.992318096,0.044192605,-0.07711256400000001,-0.07108205599999999,-0.149855908,0.038759872,-0.02747719,0.011413885,-0.075829222,-0.13421424099999998,-0.427090865,-1.8268367230000002,-2.157799469,1.0396290190000002,1.322823716,-8.73838091,-9.859851044,-7.685239365,-8.519657509,-8.507558701,-9.119597931,-7.26152844,-4.890526914,-9.455881118774414,-6.069753170013428,-10.468204498291016,-9.041417121887207,-9.64567756652832 -1051,1051,L79H,0.000578543,-0.048363297,-1.366124024,-2.62410068,-2.3376866069999997,0.034573267000000005,0.011400516000000001,-0.010243430999999999,0.26927340000000005,0.002596363,-0.09932295699999999,-1.1604122270000001,-1.5718358209999999,-2.0117372209999997,-3.2364641389999997,-2.516212746,-2.159160468,2.29428051,0.925031866,-14.11064839,-13.81050754,-11.77828395,-13.10009328,-13.463413500000001,-18.40094366,-8.004145637999999,-4.189848298999999,-14.105269432067871,-13.83675479888916,-12.020721435546875,-13.833486557006836,-15.937336921691895 -1052,1052,L79K,-0.027209036000000002,-0.8994973829999999,-2.7488818989999997,-2.66842034,-2.660157517,0.07041505299999999,-0.06577263900000001,0.011354567,0.427635892,-0.8676425809999999,-0.9313521840000001,-2.543412781,-2.954351017,-2.2741638440000003,-3.062676835,-2.380699361,-2.939615673,-0.35623305200000005,-0.6350221420000001,-15.0862654,-15.2202095,-13.30032058,-13.88620414,-13.989713,-19.03487977,-9.985118026,-7.7141849979999995,-15.499406814575195,-12.961432456970215,-17.824777603149414,-15.111091613769531,-16.631288528442383 -1053,1053,L79M,-0.041127222000000005,-7.92e-05,0.011891843000000001,0.017498071,-0.13668174800000002,0.062130882000000005,-0.028895415,-0.053359027999999996,-0.212987495,0.009610322,-0.009768671,0.048429590999999994,-0.024645906000000002,0.03058431,0.004411832,-0.064670196,-0.2086933,1.2791909540000002,2.3987463559999997,-6.232096787000001,-7.994527107000001,-5.208280418,-5.136859695,-6.139987564,-6.680829147000001,-5.200660259,-2.5376454230000003,-8.098878860473633,-6.732373237609863,-9.315922737121582,-7.955209255218506,-9.013189315795898 -1054,1054,L79N,-0.04360167400000001,0.052140272,-0.723643987,-2.0327400669999998,-2.6521134969999998,0.15569389,-0.009523327,-0.077680021,0.239310176,0.022842391,0.081438153,-0.6986852990000001,-0.748602674,-2.248980298,-1.816499835,-2.355515815,-2.948711178,1.60942797,0.6144988220000001,-14.60604326,-15.12296925,-12.10307977,-14.43522932,-14.18582407,-17.18311392,-8.929622169,-6.37161525,-15.528349876403809,-13.760026931762695,-15.80588150024414,-15.453963279724121,-17.72308349609375 -1055,1055,L79Q,0.029095556,-0.006962171999999999,-0.057202848,-1.464256965,-2.306304801,0.049686827999999995,0.032523022,0.02566809,0.20039211,-0.034112999,0.020188656,-0.08149426900000001,-0.032911427,-1.544639092,-1.383874838,-2.404502275,-2.208107326,0.8509257840000001,0.712602269,-12.89702171,-12.73980621,-10.67189474,-11.81076484,-11.49293997,-17.76970277,-8.532294561,-6.160538967999999,-12.425477981567383,-11.45993709564209,-12.535908699035645,-12.951663970947266,-14.019266128540039 -1056,1056,L79P,-0.041661111,-1.422050147,-2.334715798,-2.613714355,-3.139544463,0.065740545,-0.036098862999999995,-0.047223359000000006,0.015535506000000001,-1.4739031130000002,-1.370197181,-2.195430804,-2.474000792,-2.201404599,-3.02602411,-2.6437322169999997,-3.635356708,-0.187841378,-0.923340347,-15.212355800000003,-15.86277149,-13.32132626,-14.41690884,-14.90249727,-17.55827515,-10.88152322,-10.06790871,-16.24445152282715,-14.823440551757812,-15.697744369506836,-14.023920059204102,-18.213592529296875 -1057,1057,L79S,-0.034683821000000004,-0.026581004,-0.329449314,-1.670463279,-2.5468891190000003,0.083495357,-0.023753396,-0.045614245,0.086177239,-0.017654719,-0.035507289,-0.23302044600000002,-0.42587818200000005,-1.401052184,-1.939874374,-2.23998146,-2.853796778,2.408364335,1.4706181630000001,-13.93018694,-14.21009344,-11.30063876,-14.0202532,-14.11391738,-16.00603193,-8.822694092999999,-6.255023102000001,-13.74400806427002,-12.363579750061035,-13.997039794921875,-14.143123626708984,-15.60474967956543 -1058,1058,L79R,-0.025002387,-0.6300707720000001,-2.07486141,-2.640855904,-2.817926043,0.085764392,-0.012735762,-0.037269012000000004,0.18660382600000003,-0.559063235,-0.701078309,-2.210009851,-1.9397129690000001,-2.287548401,-2.994163406,-3.0472964310000004,-2.588555654,0.337410538,-0.510504784,-14.91602951,-15.413437099999998,-12.60615955,-13.20636533,-13.14023171,-20.21395383,-9.344230412,-6.655404396000001,-14.990522384643555,-14.321839332580566,-17.082395553588867,-14.75561237335205,-17.00029945373535 -1059,1059,L79T,0.015913008,0.00022276299999999998,-0.463125385,-1.7603153459999998,-2.2124619,0.066973833,0.017578826000000002,0.01424719,0.36424891299999995,-0.03315881,0.033604336,-0.36843225,-0.55781852,-1.4416059940000001,-2.079024697,-2.042991532,-2.381932267,3.050034408,2.029006614,-12.1605653,-12.09567677,-10.89824052,-11.17848842,-12.35365549,-14.27676527,-7.929140714,-5.677033493,-13.20191764831543,-10.448478698730469,-13.835756301879883,-13.471646308898926,-15.517451286315918 -1060,1060,L79W,-0.060461617999999995,-0.5559709820000001,-1.952050308,-2.538815624,-2.385535496,0.03155105,-0.044539752,-0.076383484,0.14017870300000002,-0.43340531,-0.678536653,-1.925785012,-1.9783156030000002,-2.434687326,-2.642943921,-2.3651315840000002,-2.405939407,1.2665556690000002,-0.068952325,-12.43776017,-13.86545841,-10.26577203,-11.42909258,-12.05515448,-14.57332337,-8.433482967,-6.189235158,-13.713098526000977,-13.90406608581543,-13.12349796295166,-13.967913627624512,-15.964179992675781 -1061,1061,L79V,-0.045812026,0.014359393,-0.0020797339999999997,-0.039006771,-1.786521316,0.067834647,-0.038276681,-0.05334737,0.001473321,0.019365586,0.009353199,0.011073528000000001,-0.015232996,0.010527672,-0.08854121400000001,-1.64900771,-1.9240349209999998,0.576076295,1.307886431,-8.534597427000001,-8.64973278,-7.34083844,-8.09098098,-8.092796036000001,-10.498638900000001,-6.740706465,-4.545376001,-10.923325538635254,-6.315739631652832,-12.058514595031738,-10.789929389953613,-11.935664176940918 -1062,1062,L79Y,-0.036318317,0.00616585,-0.431122374,-1.720367866,-3.023729688,0.048682853,-0.017739712,-0.054896922,0.31503089,0.022461263999999998,-0.010129565,-0.280711953,-0.581532794,-1.4586210480000001,-1.9821146840000001,-2.7112846,-3.3361747760000005,1.370118714,0.802306306,-12.49143999,-14.73701756,-10.55982866,-11.02231803,-11.60971087,-14.52832485,-8.090072069,-2.041093615,-12.921512603759766,-12.72195053100586,-12.90816879272461,-12.978195190429688,-14.476879119873047 -1063,1063,S80A,0.003780435,-0.000112187,-0.023835066000000002,-0.039978282000000004,0.008730478,-0.045163348,-0.005619985,0.013180853999999999,0.009412882,0.027437279,-0.027661652999999998,-0.007235320999999999,-0.040434811,-0.016718541,-0.063238022,0.013631965,0.00382899,1.129499537,2.631264114,0.658957611,0.035413863999999996,1.065093132,1.090233009,0.0018784479999999998,1.102169601,-1.3739425440000002,1.049533607,-1.8446078300476074,-0.9696612358093262,-3.6786274909973145,-3.0388431549072266,-2.5480775833129883 -1064,1064,S80C,-0.019945796000000002,-0.005649763,0.022313335,-0.003480105,-1.017420265,0.025241577999999997,-0.043087944,0.003196352,-0.000424303,0.0068516259999999996,-0.018151152,0.037051623,0.007575045999999999,0.018116052,-0.025076262000000002,-0.706796778,-1.328043751,0.6774278009999999,1.388823255,-6.109152402,-5.983003471,-7.553816521,-5.99990728,-5.361860291,-5.647174446,-6.9900029120000005,-2.7476411069999997,-7.662642955780029,-7.504413604736328,-10.04061508178711,-7.805339813232422,-9.384271621704102 -1065,1065,S80E,0.065645263,0.13345243099999998,0.070824647,0.0431435,0.100922601,0.041882749,0.07877806,0.052512465,0.010391963,0.120139854,0.146765007,0.044151964,0.09749733,-0.065543575,0.151830574,0.025852224,0.175992978,1.2051106459999998,2.659023445,-3.6246211460000004,-2.346104378,-4.472059776,-4.61055278,-2.958171516,-3.7362172780000003,-4.341704233,0.48522707299999995,-5.29832124710083,-7.3192644119262695,-5.650509834289551,-6.201848983764648,-7.998052597045898 -1066,1066,S80D,0.052241377,0.036279143,0.049174175,-0.017654791,-0.21707091899999997,-0.023723154,0.056517915999999994,0.047964837,-0.078792483,0.071720084,0.000838202,0.085544649,0.012803701,0.088448043,-0.123757625,-0.11083853,-0.323303307,1.349599622,2.3388948569999997,-2.988735117,-1.723924599,-3.115274437,-3.9605267110000004,-2.944482101,-3.199467735,-4.51670741,0.864028315,-6.394715785980225,-8.208239555358887,-6.040107250213623,-7.237947940826416,-7.95644474029541 -1067,1067,S80G,0.007324998,0.027652312000000002,0.020959051,-0.026581208999999998,-0.060435341,-0.044996303,-0.01862526,0.033275256,-0.01419731,0.068639222,-0.013334598999999999,0.015954886,0.025963216,0.0016657420000000002,-0.054828159,-0.005475071,-0.115395611,1.305254706,2.680820742,-5.03810191,-4.347550818999999,-6.180046425,-4.998769753,-4.2878851010000005,-5.376257454,-5.572651789,-2.11475684,-4.984568119049072,-6.012745380401611,-6.653980255126953,-5.801186561584473,-6.226766109466553 -1068,1068,S80F,-0.021936472000000002,0.049727858,-0.013782935,0.015995894,-0.022349997000000003,-0.046772022999999996,-0.040762226,-0.0031107170000000003,-0.034577581,0.08814697199999999,0.011308743000000001,0.043813200999999996,-0.07137907,0.020868631999999998,0.011123155,-0.016487452,-0.028212541,1.3246820540000002,2.628936646,-6.360696454,-6.457349205,-8.382338104,-6.219138152999999,-4.836637421,-5.908019386,-6.812746309,-3.5348249480000002,-8.494864463806152,-9.22844409942627,-9.929452896118164,-10.434623718261719,-9.05783462524414 -1069,1069,S80I,0.058598247,0.010656671000000001,0.036695347999999996,-0.019389035,-0.25249564,-0.121116769,0.048564033,0.06863246099999999,-0.09565490900000001,0.068755605,-0.047442263,0.07526501,-0.001874315,-0.005783563,-0.032994506,-0.216255127,-0.288736153,1.42893757,2.13258098,-6.298324435,-5.641306107,-6.815551735,-6.233091034,-5.528832367000001,-7.272840935,-7.397706917000001,-3.3897317680000003,-7.570579528808594,-8.502985954284668,-9.752264976501465,-10.430699348449707,-9.367321014404297 -1070,1070,S80H,-0.004397067,0.072688406,0.035928497000000004,0.01723173,0.034713463,-0.000986392,0.020030608999999998,-0.028824742,0.027715976,0.168619086,-0.023242274,0.110018418,-0.038161424,0.058938089000000006,-0.02447463,0.11218065,-0.04275372400000001,1.07739216,2.92220415,-3.20298566,-1.987098755,-6.339782477999999,-3.4761483610000004,-0.959738808,-3.252159897,-4.3745817360000006,0.382901216,-5.22110652923584,-6.287117958068848,-6.268796920776367,-5.75387716293335,-5.057973384857178 -1071,1071,S80K,-0.057452679000000006,-0.044111019,-0.164630083,-0.153568991,-0.065342318,-0.07902754099999999,-0.100079365,-0.014825993,0.17202957600000002,0.129712031,-0.217934068,-0.12626216199999998,-0.202998003,-0.104070105,-0.203067876,0.018755069,-0.149439705,1.287897993,2.596848787,-3.330130141,-2.146525284,-5.587464272,-4.032521255,-2.288232735,-2.595907158,-3.189259936,0.695284114,-4.729940414428711,-4.175851821899414,-5.53724479675293,-3.5394840240478516,-4.986494541168213 -1072,1072,S80M,-0.023645486,0.028413589,-0.010094269,0.003971601,-0.066786124,0.009913543,-0.098890094,0.051599122000000004,0.017987373,0.056283112999999996,0.000544065,0.034392127,-0.054580665,-0.015418477,0.023361677999999997,-0.035650611,-0.09792163699999999,1.3232182270000001,2.490043386,-5.324362936,-4.538106705,-5.782431435,-6.135371407,-4.882769035,-5.283136101,-5.615595014,-2.340792165,-6.04049015045166,-6.830935478210449,-8.312292098999023,-8.322649002075195,-7.608221054077148 -1073,1073,S80L,-0.033878732,0.0032334829999999997,-0.00977208,-0.021265886,-0.017216283,-0.080803054,-0.052288021,-0.015469442,-0.035084031,0.08743781800000001,-0.080970852,0.046162345,-0.065706504,0.038515577,-0.08104734799999999,0.022042954,-0.05647552,1.203945648,2.756117793,-4.338200618,-3.712005524,-4.7932325669999996,-4.782631912,-4.116888855,-4.286244232,-5.262522874,-1.358235053,-6.756100654602051,-8.278260231018066,-8.635376930236816,-8.660127639770508,-8.498761177062988 -1074,1074,S80N,-0.08671345,0.049912539000000006,0.025657988,0.012276138999999998,0.037980215,-0.023101176,-0.10380426300000001,-0.069622637,0.030572227999999996,0.14624426599999998,-0.046419189000000007,0.15933086300000002,-0.108014888,0.166695654,-0.142143377,0.099507291,-0.023546861000000002,1.068522011,2.96610325,-3.769201868,-2.951911552,-5.535278937999999,-4.531556114,-2.620296471,-3.206966263,-4.313887581,-0.324222475,-5.062990188598633,-6.1811933517456055,-5.74864387512207,-5.13261079788208,-5.941905975341797 -1075,1075,S80Q,0.020450486,0.078464841,0.047844936,0.051442337000000005,0.04227319400000001,0.0051349690000000005,-0.012027286000000002,0.052928257,-0.029723674,0.129502378,0.027427304,0.119402916,-0.023713045,0.087036203,0.015848471,0.104629267,-0.020082878999999998,1.0730225290000002,3.070684425,-3.529826997,-1.764112625,-6.569729691,-4.41730645,-1.632978477,-3.2650077439999996,-3.38666574,0.905837643,-4.270350456237793,-4.595521450042725,-4.4084792137146,-4.336989402770996,-4.6759819984436035 -1076,1076,S80P,-0.021013734,-0.22632506,-1.477347225,-1.9530013659999998,-2.293021701,-0.012783471000000001,-0.014290457,-0.02773701,-0.017278796000000003,-0.106669068,-0.345981052,-1.3603607290000002,-1.594333721,-1.68340233,-2.222600401,-1.842583915,-2.743459487,4.116280145,2.689273208,-7.774037581,-7.403420418,-8.542975616,-8.064102843999999,-7.209498572999999,-7.650190453,-9.046659553,-7.18566065,-10.742318153381348,-11.641809463500977,-10.702939987182617,-9.950767517089844,-11.94668960571289 -1077,1077,S80R,0.043912014000000006,0.023830552999999997,0.02109135,-0.00687618,0.006316881999999999,-0.072262985,0.045482996,0.042341032,0.01229648,0.04771220599999999,-5.11e-05,0.037250681,0.004932019,0.019911584,-0.033663942999999995,0.034362348,-0.021728584,1.216313162,2.80333895,-4.294402144,-3.115541458,-7.105670227,-4.96301696,-2.309520744,-3.97826133,-3.0527667060000003,1.5245579340000002,-5.538935661315918,-6.1681132316589355,-7.0274176597595215,-4.718228816986084,-6.514036178588867 -1078,1078,S80T,-0.021110906000000002,-0.041997509,-0.009250742,-0.024874772000000003,-0.022612891,-0.067392295,-0.018287051999999998,-0.023934759,-0.012708157,-0.003439288,-0.080555729,-0.010567761,-0.007933723,0.005606262,-0.055355805,0.00065279,-0.045878572,1.163320143,2.5198995109999998,-2.525990964,-2.48811644,-2.7397015610000004,-2.717346558,-2.192399834,-2.4923904269999997,-4.321798547,-1.148135986,-4.693789482116699,-4.629644393920898,-5.718017578125,-5.7087602615356445,-5.325647830963135 -1079,1079,S80W,-0.005498158,0.074824648,0.00672506,0.043488848,0.012556073999999999,-0.13566019199999999,-0.05538797,0.044391655,-0.093928877,0.160226389,-0.010577093000000001,0.055581425999999996,-0.04213130599999999,0.11683221099999999,-0.029854516,0.105383003,-0.080270855,1.079411031,2.92183514,-6.828069016000001,-6.330684547000001,-7.726988785,-7.298850975,-5.2123834460000005,-7.571437325,-6.522338432000001,-2.791895324,-8.533804893493652,-9.261951446533203,-10.367499351501465,-10.124826431274414,-9.29817008972168 -1080,1080,S80V,-0.008756696999999999,0.001130836,-0.021038003,-0.053764297999999995,-0.081587569,-0.100935845,0.009251823000000001,-0.026765216,-0.054204858,0.040672519,-0.038410848,-0.016725951,-0.025350054,-0.009834755,-0.09769384099999999,-0.022315281,-0.140859856,1.19428499,2.477242401,-3.78905907,-3.4845488889999996,-3.9785698089999997,-3.989531593,-3.511034958,-3.9816101,-4.766424209,-1.871814991,-6.821401119232178,-6.082479476928711,-8.90754222869873,-8.775463104248047,-8.242597579956055 -1081,1081,S80Y,0.038575432,0.046273308,0.006748659000000001,-0.029824102,0.040013894,-0.08489228,0.003971494,0.07317936900000001,0.04097022,0.056007457999999996,0.036539157,-0.00119747,0.014694786999999999,-0.05283594,-0.006812264,0.0017441029999999999,0.078283685,1.198251489,2.6299958880000003,-5.023483173,-4.383644653,-8.256493637,-5.101976379,-2.106969383,-5.26833181,-5.262635241,-1.387936311,-7.36361026763916,-8.299697875976562,-8.686807632446289,-8.758424758911133,-7.585604667663574 -1082,1082,R81A,-0.017815333,-0.01776894,-0.037088676,-0.021613384,-0.188147805,0.009769238000000001,-0.06681864400000001,0.031187977999999998,-0.039554076,-0.0015434429999999998,-0.033994436,-0.023585909,-0.050591443,-0.034647541000000004,-0.008579226,-0.18541005800000002,-0.19088555100000001,1.621299332,2.325708276,-6.800035385,-5.662657303,-6.267086578,-7.778174507,-7.584325661,-6.707932877,-5.924910882000001,-0.9334941240000001,-9.779597282409668,-9.894207000732422,-8.125627517700195,-7.978959560394287,-10.561273574829102 -1083,1083,R81C,-0.027420629,-0.004582591,-0.031563928,-0.371294341,-1.624129056,0.10201629699999999,0.001005894,-0.055847151,0.0163518,-0.016699436,0.007534255,-0.05452100000000001,-0.008606856,-0.22171987899999998,-0.5208688029999999,-1.690131812,-1.558126299,1.337254274,1.374435638,-9.70629068,-8.691199425,-10.29591684,-10.34909089,-9.532753937,-9.66249231,-7.304108984,-4.419697544,-11.838534355163574,-11.276653289794922,-8.95627498626709,-11.096025466918945,-10.881591796875 -1084,1084,R81E,-0.018979202,-0.012774246999999999,-0.03799178,-0.015531669,-1.4667390530000002,0.068227587,-0.011197166000000001,-0.026761238,-0.034149317,-0.054504919000000006,0.028956425,-0.063556895,-0.012426665,-0.048918305999999995,0.017854968,-1.495404654,-1.4380734519999998,0.748324407,1.324960167,-6.38438447,-5.056917946,-7.0191589510000005,-6.903066657999999,-7.142991837,-5.799786957,-5.324598647,-0.923295405,-11.807896614074707,-11.339179992675781,-10.44304370880127,-9.859728813171387,-11.990791320800781 -1085,1085,R81D,3.77e-05,0.00793268,-0.03210496,-0.446090128,-1.5815176690000001,-0.035873802999999996,-0.010694901000000001,0.010770298999999999,-0.005869676999999999,-0.031195233,0.047060592000000005,-0.020556543,-0.043653377,-0.23871049600000002,-0.653469759,-1.737491345,-1.425543993,1.350288875,1.368310013,-6.6262499770000005,-4.281867355,-7.593464813,-5.950424011,-6.638147292999999,-8.667346412999999,-5.382875144,-1.1567101770000001,-13.023324966430664,-12.320533752441406,-11.243233680725098,-10.427314758300781,-13.044897079467773 -1086,1086,R81G,-0.061778215,-0.028050445,-0.077628369,-0.043402497000000005,-1.513572123,0.006583006999999999,-0.08633876,-0.037217669,-0.021909968999999998,-0.035025985,-0.021074904,-0.069222768,-0.086033969,-0.045869372,-0.040935622000000005,-1.382198379,-1.644945867,0.8268371309999999,1.3389096740000002,-6.2304477810000005,-6.390813652,-6.592454575,-6.83187487,-6.007526642,-5.329569168,-5.579214821,-2.178875398,-11.767108917236328,-11.049027442932129,-9.589571952819824,-9.311264038085938,-12.083395004272461 -1087,1087,R81F,0.059842322,0.068162342,0.025830263,0.001161222,-0.699796092,0.094903217,0.052666066,0.067018577,-0.09909509400000001,0.027263447000000003,0.10906123699999999,-0.004547025,0.056207550999999994,-0.053453357,0.05577580099999999,-0.573211047,-0.826381136,1.3592227780000001,1.6924534480000002,-11.70878268,-9.998816872,-11.7766423,-12.72111183,-10.320478199999998,-13.72686418,-7.837640966,-4.27556118,-12.412363052368164,-14.553396224975586,-12.49549674987793,-13.006916046142578,-12.73909854888916 -1088,1088,R81I,-0.000672619,0.037720929,-0.046975253,-0.0584146,-1.42389794,0.027153487999999996,-0.026017684,0.024672446,-0.070179215,-0.023855211,0.099297068,-0.028326112,-0.065624393,-0.054696960999999995,-0.062132239000000006,-1.1653607129999999,-1.6824351659999999,0.888948216,1.366223025,-10.75231271,-10.46017023,-10.48652612,-12.96393156,-9.663714577,-10.18722108,-8.527733181,-5.707633559,-11.078367233276367,-14.189355850219727,-12.041131973266602,-12.099591255187988,-12.304426193237305 -1089,1089,R81H,-0.08531382800000001,-0.035217379,-0.101156614,-0.039854742,-0.321205933,0.001246909,-0.112464596,-0.05816306,-0.015215191999999999,-0.032504757999999995,-0.03793,-0.0455228,-0.15679042699999998,-0.018971915,-0.060737568,-0.185042156,-0.45736971,1.238500805,2.015814537,-6.045845535,-6.433644714,-6.127481461,-6.044689902999999,-5.746162781000001,-5.877248817000001,-6.431439571,-3.055176,-9.043008804321289,-9.751226425170898,-7.876862525939941,-7.963819980621338,-9.284746170043945 -1090,1090,R81K,-0.043906191,-0.0666552,-0.052535839,-0.074443465,-0.051616290999999995,-0.048374096,-0.05829417,-0.029518212000000002,-0.044841455999999995,-0.07595604,-0.057354359,-0.043955435999999994,-0.061116242,-0.058836501,-0.090050429,-0.064151378,-0.039081204,1.334835492,2.373449504,-3.9808057339999996,-4.303813393,-4.020109375,-3.6353725889999997,-3.3626632689999996,-4.582070045,-4.312134604,-0.8245219540000001,-5.90305757522583,-5.827164649963379,-4.3369574546813965,-5.203438758850098,-6.953810691833496 -1091,1091,R81M,-0.036461006000000004,-0.031057745,-0.058285708,-0.087047375,-0.186559753,0.002318691,-0.105449437,0.032527425,-0.11362440300000001,-0.014829525,-0.04728596400000001,-0.017651552,-0.09891986400000001,-0.072462026,-0.10163272300000001,-0.13698518199999998,-0.23613432399999998,1.345279514,2.160178499,-8.79054639,-8.778355522,-8.485091591,-11.23664427,-7.553442245,-7.899198318,-6.680057505,-2.620263835,-9.746668815612793,-10.598882675170898,-7.999613285064697,-10.256608009338379,-9.920254707336426 -1092,1092,R81L,0.010610116000000001,0.008759646,-0.022884488999999997,-0.026334056,-0.179219629,-0.05354498,-0.006990693,0.028210924,-0.012710508999999998,-0.026509479,0.04402877,-0.035876592,-0.009892386,-0.039205909,-0.013462203,-0.16088729,-0.197551968,1.458192345,2.233501817,-6.114860832000001,-5.912994293,-6.153731232,-8.853515739,-4.909612686,-4.744450211,-5.038215288,-1.3788029380000002,-7.781662940979004,-9.177472114562988,-7.8032121658325195,-9.334095001220703,-8.600236892700195 -1093,1093,R81N,-0.014860759,-0.042889953,-0.051431365,-0.07123174,-0.23924434100000003,0.045580851,-0.043544014000000006,0.013822497,0.0077538880000000004,-0.06874627700000001,-0.017033628999999998,-0.08671964800000001,-0.016143081,-0.09111174699999999,-0.051351733,-0.269564337,-0.20892434399999998,1.54860694,2.093003216,-6.886143845,-6.066132339,-7.4382342,-6.6212352679999995,-6.693255035,-7.611862381,-5.65073081,-3.1703742010000004,-10.906352043151855,-10.585529327392578,-9.274231910705566,-8.495473861694336,-10.911312103271484 -1094,1094,R81Q,-0.07544084200000001,-0.013630202,-0.041055384,-0.06362775700000001,-0.21571248399999998,0.014635173000000001,-0.12050081300000001,-0.030380871,-0.005751541999999999,-0.018338911,-0.008921492,-0.015756527,-0.066354241,-0.073571796,-0.053683718,-0.21074081,-0.22068415800000002,1.4980799930000002,2.163044811,-4.171325552,-4.1288100739999996,-4.421803307,-4.655102363999999,-4.47781218,-3.173099838,-4.897855894,-0.111195313,-8.154488563537598,-7.699811935424805,-6.0774827003479,-7.123180389404297,-8.59427261352539 -1095,1095,R81P,-0.01483925,-0.69609483,-1.9631276290000002,-2.303597255,-3.0626889810000004,0.020189225,-0.017343092,-0.012335408,0.052303867999999996,-0.668372719,-0.7238169409999999,-1.987376085,-1.9388791719999998,-2.271392863,-2.335801647,-2.761573541,-3.36380442,1.542243778,-0.077424439,-12.05395426,-11.28890859,-12.19080585,-12.91754662,-11.75264608,-12.11986417,-10.47997372,-8.924126087000001,-15.388786315917969,-16.568668365478516,-12.093629837036133,-15.132288932800293,-16.706010818481445 -1096,1096,R81S,-0.058701185,-0.018177864,-0.047342122,-0.063619816,-0.725978424,0.018582156000000002,-0.090715627,-0.026686742000000003,0.036326305,-0.029540699,-0.006815029,-0.039176572,-0.055507670999999995,-0.089006931,-0.0382327,-0.558122376,-0.8938344709999999,2.637138447,2.8025822989999996,-8.082844467000001,-7.68767189,-7.857932404,-8.149855293,-8.649837311,-8.068925437999999,-6.28861819,-3.10536493,-10.844615936279297,-10.811396598815918,-9.052906036376953,-8.851545333862305,-10.708643913269043 -1097,1097,R81T,-0.08529094,-0.034426002000000004,-0.036001014,-0.016455654,-1.7759954980000001,0.04017739,-0.08787570800000001,-0.082706171,-0.002839185,0.008759449,-0.077611452,-0.007364546,-0.064637481,0.0030162009999999996,-0.035927508,-1.4337760480000001,-2.118214947,0.7494570690000001,1.328478104,-8.578649541,-7.802854583999999,-7.99684375,-8.750476943999999,-9.053988937,-9.289083488,-6.637558929,-3.444158613,-11.855998039245605,-12.078948974609375,-10.605249404907227,-9.8141508102417,-11.963410377502441 -1098,1098,R81W,-0.08974804300000001,-0.010538216999999999,-0.045731472,0.010094935,-1.456464756,0.0027228940000000004,-0.07125141900000001,-0.10824466599999999,0.000596738,0.029746319,-0.050822753,0.0013326739999999998,-0.09279561800000001,0.059017517,-0.038827648,-1.582226414,-1.3307030979999999,0.33883221799999996,1.304335829,-10.58305488,-9.950487396,-11.05831363,-11.6150691,-9.473591599,-10.81781265,-7.966318982000001,-4.033403742,-11.517313003540039,-12.19300651550293,-11.186793327331543,-12.066725730895996,-10.439210891723633 -1099,1099,R81V,-0.052987957,-0.040181674,-0.054805575,-0.053949295,-1.659967983,0.022825507999999998,-0.086713906,-0.019262007,-0.028455652999999997,-0.020298015,-0.060065332,-0.006401751,-0.10320939800000001,-0.031716881,-0.076181708,-1.417848297,-1.902087668,0.8175539159999999,1.335688426,-9.648307803,-8.572995628,-9.30253653,-11.75603367,-9.166711998,-9.443261192000001,-7.673170004,-4.873921903,-12.289421081542969,-13.514568328857422,-12.274943351745605,-11.733823776245117,-12.838031768798828 -1100,1100,R81Y,-0.031394298,-0.003046713,-0.0157521,-0.006147488,-0.680618794,-0.019064964,-0.050582142000000004,-0.012206453,-0.029537555,-0.004107189,-0.001986237,-0.042051640999999994,0.010547441999999999,-0.019286094,0.006991118,-0.635358954,-0.725878633,0.849181324,1.447754335,-11.56392999,-11.493609199999998,-12.70887596,-11.64326144,-10.271834199999999,-11.70206918,-8.050760456,-2.897884873,-12.026041030883789,-13.944625854492188,-11.569387435913086,-12.519594192504883,-12.323932647705078 -1101,1101,V82A,0.02364608,0.00657732,0.022050464,0.010293498,-0.11599150800000001,0.049146985,0.04257509,0.00471707,0.040949753,0.019986003000000002,-0.006831363000000001,0.023909008,0.02019192,0.00474556,0.015841436,-0.09631918099999999,-0.135663835,1.302304122,2.266527397,-4.6474002610000005,-3.408050621,-4.909441437,-3.566066582,-5.317224648,-6.036218018,-2.267512075,-0.787048559,-7.359254360198975,-7.9342360496521,-7.887991905212402,-6.832863807678223,-7.551255702972412 -1102,1102,V82C,-0.012873497,-0.00978831,0.001146796,0.001306052,-0.161156887,0.07720748,-0.022516196000000002,-0.003230798,-0.009759837,0.035038741,-0.05461536,0.037105801,-0.03481221,0.037451523,-0.034839418999999996,-0.086343059,-0.235970714,1.458823433,2.5991132059999997,-9.147447332999999,-6.947304535,-9.09932254,-9.024100281,-10.51731407,-10.14919524,-5.475818752,-4.047848571,-10.945390701293945,-10.35031509399414,-11.1936674118042,-7.784357070922852,-12.106267929077148 -1103,1103,V82E,-0.059003195999999994,0.053682252,-0.002924168,-0.09608156400000001,-1.8946938290000002,0.077585552,-0.016096831000000002,-0.101909561,0.17430035100000002,0.01900518,0.088359324,-0.022771613,0.016923277,-0.026206074,-0.16595705300000002,-1.6854088719999998,-2.103978786,0.839385899,1.3196498140000001,-9.44456954,-9.024781723,-8.923182022,-8.439155861,-8.446253319,-12.38947478,-5.451898495,-3.528226316,-12.36122989654541,-13.215845108032227,-12.74940299987793,-11.965987205505371,-11.375003814697266 -1104,1104,V82D,-0.078538422,-0.069542888,-0.058260386,-0.7914231540000001,-1.850754,0.029783281,-0.071522892,-0.08555395199999999,0.013721259,-0.055964568,-0.083121207,-0.047862265,-0.068658506,-0.558429747,-1.02441656,-1.71252529,-1.988982709,1.941869632,1.553586766,-10.15743529,-9.583403831,-7.125161446,-9.646863174,-10.81224039,-13.61950761,-5.117557733,-3.3922258889999997,-13.944703102111816,-13.4613037109375,-13.9085693359375,-12.119230270385742,-13.671936988830566 -1105,1105,V82G,-0.040222061,-0.0062716790000000005,-0.031501978,-0.138420779,-1.77800061,0.07144250099999999,-0.013028369,-0.067415753,-0.22156664899999998,-0.004367659,-0.008175698,-0.037897592,-0.025106364,-0.06462538799999999,-0.21221616899999998,-1.584244913,-1.971756307,0.752884442,1.320207154,-9.676449418999999,-10.06672876,-9.425390625,-7.787416611,-8.633965309,-12.46874579,-4.254121747,-3.499390659,-12.30263614654541,-12.893333435058594,-13.363286018371582,-11.337409019470215,-13.130927085876465 -1106,1106,V82F,-0.031345183,-0.007771254,-0.039456959,-0.020351678999999998,-1.633488879,0.032345099,0.0033134909999999996,-0.066003856,0.104183515,0.00012154,-0.015664047,-0.013172891,-0.06574102700000001,-0.005633079,-0.035070278999999996,-1.50128468,-1.7656930769999999,0.586450482,1.31512768,-11.0659356,-11.07965033,-11.01479855,-9.10072644,-9.669673569,-14.46482912,-6.019152891,-3.1897140439999996,-10.982266426086426,-11.316234588623047,-10.840106010437012,-9.850973129272461,-11.060296058654785 -1107,1107,V82I,-0.018774182,0.014332528999999998,-0.0042989840000000005,-0.012213768,-0.06747542200000001,0.041422819,0.00141366,-0.038962024,0.020203386,0.045709423,-0.017044366000000002,0.023198406,-0.031796374,0.017611902,-0.042039438,-0.046753135999999994,-0.08819770800000001,1.2133435590000001,2.3989563869999997,-3.3794687239999996,-3.330043068,-2.793114372,-3.2392656630000003,-3.8919751739999997,-3.642945343,-1.7010873530000001,-1.168657654,-5.853253364562988,-3.318892002105713,-5.98226261138916,-5.020330905914307,-4.9559431076049805 -1108,1108,V82H,-0.023783006000000002,-0.040903918,0.004089641,-0.044471660999999996,-0.512638539,0.092888544,-0.013847672,-0.033718339,-0.018741136000000002,-0.002348656,-0.079459179,-0.024465057999999998,0.03264434,-0.00027524200000000003,-0.08866808,-0.346971627,-0.678305451,0.855719929,1.5676554040000001,-9.467669061,-9.169349709,-8.645125046,-9.460372177,-7.645638152999999,-12.41786022,-4.46330427,-2.680930702,-12.302886009216309,-12.439699172973633,-11.317407608032227,-10.69426155090332,-12.81358528137207 -1109,1109,V82K,-0.041214192999999996,0.019099755,-0.027513819,-0.027753198,-1.543739055,0.060878349000000005,-0.025113066,-0.057315319,0.388180171,0.035380287999999996,0.002819221,-0.039501048999999996,-0.015526588000000001,0.0009497939999999999,-0.05645619,-1.632879309,-1.454598801,0.72628651,1.3156305190000002,-8.873556502000001,-9.74367495,-8.512688156,-8.347307198,-6.9497876970000005,-10.81432451,-3.9874037510000004,-3.477587174,-11.475939750671387,-11.258363723754883,-12.960163116455078,-9.3370943069458,-12.42664623260498 -1110,1110,V82M,-0.068743266,-0.012698853999999999,-0.01737977,-0.04834492,-1.392685652,0.072471692,-0.020541655,-0.116944876,-0.126729644,0.042770717,-0.068168425,0.014050816,-0.048810356,-0.001215627,-0.095474213,-1.4068491280000002,-1.378522175,0.6487829279999999,1.322662941,-8.47711888,-8.170028397000001,-8.728244576,-7.295127852999999,-7.146078285,-11.04611529,-5.409819682,-3.230782262,-9.610389709472656,-8.865148544311523,-9.978145599365234,-8.354973793029785,-9.403877258300781 -1111,1111,V82L,-0.052796090999999996,0.010679283999999999,-0.024765829,-0.077961666,-1.847136171,0.11714804,-0.022602367999999998,-0.082989813,0.00428324,-0.003998797,0.025357364,-0.020066959,-0.029464697999999998,-0.038125001,-0.11779833,-1.659532143,-2.0347401990000002,0.759445048,1.316529467,-6.8948638529999995,-7.161237907,-7.35237542,-6.1226580120000005,-5.122457077,-8.715590851,-3.778675433,-1.9220325919999999,-8.417810440063477,-7.90730094909668,-8.064987182617188,-6.229946136474609,-8.48574161529541 -1112,1112,V82N,-0.047923674000000006,0.004200988,-0.004557653,-0.021605915,-2.000244548,0.081369188,-0.039049658,-0.056797689000000005,-0.037788561,0.036353376,-0.027951401,-0.003224453,-0.005890853000000001,-0.013352646000000001,-0.029859182999999997,-1.424794087,-2.5756950080000003,0.69210085,1.324587508,-9.815535732999999,-9.760730773999999,-9.20993589,-8.805533226,-8.534450828999999,-12.76702795,-4.542852859,-2.636820663,-11.625265121459961,-9.51959228515625,-11.455602645874023,-9.85623550415039,-12.51703929901123 -1113,1113,V82Q,0.016821400000000004,0.025459227,0.012456552,0.031384089,-1.4728260119999999,0.059906694,0.043896261,-0.010253461,0.001235547,-0.049291389000000005,0.100209843,-0.006590596,0.0315037,0.039168805,0.023599372,-1.443618957,-1.502033067,0.705085727,1.324073152,-7.719080127000001,-8.13672583,-7.440542206,-6.9485734710000004,-6.264174324,-9.805384804,-4.8781962860000005,-4.043456638,-10.967023849487305,-11.565435409545898,-11.859445571899414,-10.191954612731934,-11.645234107971191 -1114,1114,V82P,-0.060577883,-0.444607139,-1.805983155,-2.313036301,-2.960805997,0.066681031,-0.045552040999999995,-0.075603725,-0.015154869,-0.348339794,-0.540874483,-1.729608552,-1.8823577569999999,-2.086410972,-2.5396616290000003,-2.589841189,-3.3317708039999996,2.898189882,1.123066537,-12.06667736,-11.55962688,-11.63977038,-11.39539185,-11.51399146,-14.22460622,-7.130731583999999,-6.410174892000001,-15.125521659851074,-14.90835952758789,-14.388866424560547,-13.345063209533691,-15.875161170959473 -1115,1115,V82S,-0.013675603,-0.017376661,-0.024745926,-0.020762809,-0.6543946820000001,0.065393824,0.0057236940000000005,-0.033074900000000004,0.030088794,-0.007746736,-0.027006586000000003,-0.028954336,-0.020537515,-0.025118663,-0.016406953999999998,-0.450547638,-0.8582417259999999,1.17377588,1.6660552419999999,-7.909236185,-6.307212875,-8.508007462,-6.696260139,-7.11675856,-10.91794189,-3.533072753,-1.8291327030000002,-9.9425687789917,-8.660762786865234,-11.211782455444336,-9.086433410644531,-10.06682300567627 -1116,1116,V82R,-0.012756503999999998,0.014615683999999999,-0.008757603000000001,-0.016316637,-1.5383483409999998,0.07354786599999999,0.015530325,-0.041043333,0.073139461,0.004136941,0.025094427000000002,-0.029440592999999998,0.011925388,-0.035566613,0.00293334,-1.409227671,-1.66746901,0.8236145709999999,1.3360488640000001,-8.512771008,-8.73029496,-8.85192524,-9.373841057,-5.716705711,-9.891088073999999,-4.416342965,-2.7442010760000004,-11.433035850524902,-11.928756713867188,-12.68238353729248,-7.2832560539245605,-12.749513626098633 -1117,1117,V82T,-0.052854029000000004,-0.021538877999999997,-0.01449999,-0.01136095,-0.458571735,0.087370302,-0.022969603999999998,-0.082738454,-0.20812749100000003,0.023438956,-0.066516712,0.01566734,-0.044667319000000004,-0.002291039,-0.020430861,-0.348260726,-0.568882743,0.968915868,1.644018406,-7.23696767,-6.5613636170000005,-6.701391677999999,-6.385270432,-7.557248085,-8.979564537,-4.389713005,-2.836076644,-8.567626953125,-5.507112503051758,-9.35978889465332,-7.722171783447266,-8.139881134033203 -1118,1118,V82W,-0.000279048,0.034775789,-0.010688762,-0.00051615,-1.504499223,0.033329727999999996,0.012673876,-0.013231971,-0.14693303,0.021637745,0.047913832,0.02195761,-0.043335133,-0.015612948,0.014580649,-1.294401516,-1.714596929,0.794965875,1.34204934,-11.88271622,-11.70707121,-12.24678862,-10.80878152,-10.6539921,-13.99694765,-7.065927137999999,-6.523346105,-13.612252235412598,-14.844169616699219,-13.170406341552734,-12.858470916748047,-14.626474380493164 -1119,1119,V82Y,-0.100965825,-0.068454665,-0.060176226,-0.059228178,-1.331138427,0.006738443,-0.097752696,-0.104178954,0.087150176,-0.001023239,-0.13588609,-0.013939246,-0.106413206,-0.035440396,-0.08301596,-0.968995306,-1.6932815469999998,0.888955534,1.389953297,-11.88190003,-11.32664417,-11.14407112,-10.08856184,-10.84800731,-16.00221573,-5.330620742,-3.288971544,-12.57086181640625,-12.568796157836914,-10.530977249145508,-10.79739761352539,-11.745453834533691 -1120,1120,D83A,-0.143561675,-0.077570233,-0.043032293,-0.082331328,-1.691802754,0.006720323,-0.117421006,-0.169702343,0.013509291000000001,-0.030007764,-0.12513270199999998,-0.017870126,-0.068194459,-0.030963038,-0.133699617,-1.530732881,-1.8528726269999998,0.59473498,1.313506819,-8.519157535,-6.152644264,-8.595246207999999,-12.61904709,-6.224148727,-9.004701386,-4.721784029,-1.446622053,-10.231274604797363,-8.825166702270508,-11.81033706665039,-7.663651466369629,-11.391494750976562 -1121,1121,D83C,-0.118593263,-0.08873477199999999,-0.022321828999999998,-1.3846417640000002,-2.6887639219999997,0.076148557,-0.088627235,-0.14855929,-0.021465397999999997,-0.09406313599999999,-0.083406408,-0.019283795,-0.025359862,-1.234441939,-1.5348415880000001,-2.171129604,-3.20639824,2.274892404,1.470178547,-13.89365689,-11.69398572,-14.1157723,-18.0742255,-12.02309994,-13.56120098,-9.177172791,-6.657912106,-13.882585525512695,-15.03858757019043,-16.607154846191406,-13.120195388793945,-16.530702590942383 -1122,1122,D83E,-0.009370508,-0.002254833,0.04483406,-0.005885425,-0.09605175199999999,0.015333734,-0.019521708000000002,0.0007806930000000001,0.01627343,0.024349898,-0.028859562999999998,0.05672539099999999,0.032942728,-0.017884594,0.006113745,-0.092954356,-0.099149148,1.2738711120000001,2.314091754,-4.65389301,-3.583685799,-4.621085953,-7.125994307999999,-4.160987114,-3.777711876,-4.141857461,-0.83423194,-6.454052925109863,-5.65004825592041,-7.576328754425049,-5.545382976531982,-7.222414970397949 -1123,1123,D83G,-0.073048334,-0.050513363,-0.026441369,-0.10738702,-1.86508199,0.056989477999999996,-0.075360657,-0.07073601,-0.062158255999999995,-0.022319019,-0.078707706,-0.015416006000000001,-0.037466731,-0.07831421599999999,-0.136459823,-1.668188726,-2.061975253,0.8085623940000001,1.318748343,-9.050316156000001,-6.476024727,-9.44026255,-12.43665324,-7.560489067000001,-9.338151192,-6.669162387,-3.191356227,-11.216889381408691,-10.071044921875,-12.41389274597168,-8.893488883972168,-11.597949981689453 -1124,1124,D83F,-0.100942685,-0.05938765,-0.693523178,-1.763186097,-2.7042285,-0.031874635,-0.053523812999999996,-0.148361557,-0.067506537,-0.056850945,-0.061924355,-0.481617704,-0.905428652,-1.806536775,-1.7198354180000002,-2.518284614,-2.890172386,1.714657734,0.812253335,-14.83520027,-13.224511800000002,-14.54475845,-19.77143609,-13.35689011,-13.27840491,-8.714902588,-5.54722907,-14.299400329589844,-14.887930870056152,-16.8511905670166,-13.384811401367188,-16.566991806030273 -1125,1125,D83I,-0.06319135599999999,-0.07435249299999999,-0.078379838,-1.624806584,-2.0169373090000002,-0.050926484,-0.076211955,-0.050170757,-0.10930345400000001,-0.093428941,-0.055276044,-0.03394733,-0.122812346,-1.5080074540000001,-1.7416057130000002,-2.051350862,-1.982523755,1.264451243,0.775584791,-14.28678784,-13.83390658,-13.79460052,-18.30379232,-11.19114969,-14.31049007,-8.226362598,-5.824854521000001,-13.304545402526855,-14.132341384887695,-15.443979263305664,-11.269769668579102,-15.533106803894043 -1126,1126,D83H,-0.040206122000000004,-0.021761912999999997,0.014776724,-0.89984618,-2.269238258,0.028223766,-0.045361045,-0.035051199,-0.020002773999999997,-0.052112566,0.008588741,-0.012141029,0.041694476,-0.6619798339999999,-1.137712525,-1.937293507,-2.601183008,1.778420294,1.387911765,-8.782961143,-7.062699951,-8.289400185,-11.947687400000001,-6.671564697000001,-9.943453483999999,-6.451487386,-3.1292459580000003,-11.85268497467041,-10.573322296142578,-13.282150268554688,-9.37108325958252,-11.875762939453125 -1127,1127,D83K,-0.066975436,-0.062170925999999994,0.015089411,-0.778854708,-2.1947560619999997,-0.014355165,-0.054376851,-0.079574021,-0.026359147000000003,-0.06688298200000001,-0.057458869,-0.003928095,0.034106917,-0.49472931200000003,-1.062980103,-1.895307523,-2.4942046,1.70283385,1.4132134159999998,-9.779066435,-7.842997391,-9.531024261,-13.81035509,-8.239339232999999,-9.471616196,-6.631604959,-2.467816243,-13.466477394104004,-11.684158325195312,-13.669526100158691,-9.137351989746094,-13.238653182983398 -1128,1128,D83M,-0.22410914399999998,-0.042628952000000005,-0.011138499,-1.053161372,-1.688388499,-0.034895092,-0.000627996,-0.44759029100000003,-0.072682259,-0.049474707,-0.035783196,-0.032274267,0.009997269,-0.832414908,-1.273907836,-2.0346479619999998,-1.342129035,2.182409577,1.5571879640000001,-13.53412581,-12.95069685,-13.18175354,-17.60739271,-10.87182018,-13.05896579,-7.001499837999999,-3.756477765,-12.956487655639648,-13.313138961791992,-15.633674621582031,-11.612143516540527,-15.843673706054688 -1129,1129,D83L,-0.051338605,-0.054474568,-0.234739452,-1.557010919,-2.734828189,-0.074519116,-0.060754964,-0.041922245,0.009934126,-0.05093954,-0.058009596,-0.144246348,-0.325232556,-1.488490555,-1.6255312819999999,-2.401883757,-3.067772621,1.078478698,0.7438535279999999,-13.25972813,-12.93115707,-12.94427644,-17.68989948,-10.22863145,-12.504676199999999,-6.708215899,-4.115099478,-13.058785438537598,-13.372701644897461,-15.373700141906738,-11.339884757995605,-15.748651504516602 -1130,1130,D83N,-0.006401794000000001,-0.023130018,-0.010393307,-0.09137129199999999,-2.019126225,0.068659931,0.00041739,-0.013220978000000001,0.12263000800000001,-0.022490892000000002,-0.023769143,0.010401968000000001,-0.031188582000000003,-0.09853483,-0.08420775400000001,-1.64263949,-2.395612959,0.9493019890000001,1.330980288,-8.325561273,-6.723494591000001,-7.318970222000001,-10.52313324,-7.812162979,-9.250045334,-6.763334443,-3.1634390210000003,-9.205705642700195,-8.868793487548828,-9.627939224243164,-7.076377868652344,-9.784133911132812 -1131,1131,D83Q,-0.050964392000000004,-0.060644755,-0.007093006999999999,-0.034668355,-0.307681489,0.049741424000000006,-0.054026252999999996,-0.04790253,0.008411670999999999,-0.04916627,-0.072123239,0.031045121000000002,-0.045231134000000006,-0.023164475,-0.046172235,-0.258154029,-0.357208949,1.184503074,1.828495987,-8.491979831,-6.638057159,-8.752480621,-11.25586845,-7.513218628,-8.3002743,-5.000106645,-2.026122101,-10.504463195800781,-8.483634948730469,-11.135839462280273,-7.8359527587890625,-11.210861206054688 -1132,1132,D83P,-0.045632229,-0.04578213,-1.107685106,-1.8696608890000002,-2.9442891560000004,0.08039247599999999,-0.042558857,-0.048705600999999994,0.01024835,-0.03603298,-0.05553128,-1.0210106140000001,-1.194359598,-1.822325786,-1.9169959909999998,-2.722064107,-3.166514205,2.403499216,1.093923145,-11.95670678,-7.556582855,-12.70277243,-16.56848303,-11.25630791,-11.69938768,-5.638249076,-2.437532398,-17.52873992919922,-14.466848373413086,-16.887287139892578,-11.705046653747559,-19.080656051635742 -1133,1133,D83S,-0.071765283,-0.054451769000000004,-0.007096241,-0.048088055,-1.653496975,0.060788668,-0.058814077,-0.084716489,0.024441848,-0.053338178,-0.05556536,-0.005111203,-0.009081278,-0.041785833,-0.054390277,-1.454932169,-1.852061781,0.582119371,1.316706729,-9.400484158,-6.341538185,-9.508948952,-13.45557604,-8.23358873,-9.462768882999999,-5.763813821,-1.8187459240000001,-10.589486122131348,-9.693973541259766,-12.21117115020752,-8.65910816192627,-11.631038665771484 -1134,1134,D83R,-0.059269045,-0.05405598599999999,-0.014104799,-1.167210791,-2.109991013,0.021319551000000003,-0.069524413,-0.049013677,-0.027924746,-0.043460467999999995,-0.064651503,-0.015654635,-0.012554962,-0.8488593990000001,-1.4855621819999998,-2.053103354,-2.1668786719999997,2.028604267,1.454498099,-8.791749467,-8.729455292,-6.804651825,-11.909795599999999,-7.370089973,-9.144754646,-5.514707105,-2.391647065,-14.75867748260498,-13.336750030517578,-15.210599899291992,-11.099760055541992,-14.711923599243164 -1135,1135,D83T,-0.121552342,-0.066930593,-0.017447223,-0.159290823,-1.7427471159999999,0.064186385,-0.025454888,-0.217649796,-0.02237912,-0.060446753,-0.073414432,-0.032360832,-0.002533613,-0.130702218,-0.18787942800000001,-1.692576649,-1.7929175819999998,0.883727947,1.321358139,-10.39226464,-7.58237458,-11.14175458,-14.72469881,-7.378234192000001,-11.13426103,-6.491447456,-2.7676608,-11.560863494873047,-10.939006805419922,-13.552560806274414,-9.258499145507812,-12.878023147583008 -1136,1136,D83W,-0.048484868,-0.058698985,-0.80763949,-1.92369875,-2.996894747,-0.03183439,-0.044640554000000006,-0.052329180999999995,-0.017897527,-0.040197128,-0.07720084099999999,-0.748996198,-0.8662827820000001,-1.8831007530000001,-1.964296746,-2.7197873280000002,-3.2740021660000003,2.02523711,0.891066295,-13.78739878,-12.60462251,-12.54378258,-18.12429844,-12.50774976,-13.15654062,-8.640079494,-5.882583966,-16.08123207092285,-16.957523345947266,-18.144254684448242,-15.349794387817383,-18.052894592285156 -1137,1137,D83V,-0.194687721,-0.043709894000000006,0.00433854,-1.1913334740000001,-1.970337587,0.068547263,-0.041454931,-0.347920511,-0.044843707999999996,-0.082044122,-0.005375665,-0.009818369,0.018495448,-0.925719553,-1.456947394,-1.932745058,-2.007930115,2.292506093,1.6327251719999998,-11.96765676,-11.60577998,-11.36696789,-15.98356109,-8.87623877,-12.00573608,-6.386846036000001,-3.516900655,-12.383248329162598,-12.310382843017578,-14.61066722869873,-10.096946716308594,-13.880356788635254 -1138,1138,D83Y,-0.081532647,-0.042175975,-0.247448463,-1.858446232,-2.889481787,0.061175584000000005,-0.106669741,-0.056395552,-0.067497575,-0.057920317,-0.026431633,-0.140994643,-0.353902283,-1.5197033000000002,-2.197189164,-2.9304211419999997,-2.8485424310000003,1.137069645,0.751699023,-13.7126861,-11.46433321,-14.88670873,-17.7519307,-12.77996906,-11.68048882,-8.263954348,-4.720137402,-14.211576461791992,-13.706212043762207,-15.08558464050293,-11.850985527038574,-14.591909408569336 -1139,1139,A84C,0.008774747,0.01381661,0.023578695,-0.012594668,-0.438931888,0.078524336,-0.012519162,0.030068655,-0.052781210999999995,-0.0030723240000000004,0.030705543,0.06258254,-0.015425151000000002,-0.012960788,-0.012228548,-0.327870542,-0.5499932329999999,1.028906061,1.673434527,-6.414064891000001,-5.184808876,-7.555640228,-6.472646484,-5.9738189539999995,-6.883409912,-7.05757314,-4.599009324,-8.694403648376465,-8.984983444213867,-9.22266674041748,-8.656725883483887,-10.139106750488281 -1140,1140,A84E,0.112527629,0.050621837,-0.017094731000000002,0.016002861,-2.34e-05,-0.019062756,0.151369934,0.073685323,0.103381615,-0.034314774,0.135558448,-0.06354565400000001,0.029356192000000003,-0.009165286,0.041171007999999995,-0.126622498,0.12657564699999999,1.383604708,2.246476384,-2.665904166,-1.4761604,-3.562977394,-4.179887238,-1.925609177,-2.18488662,-4.22914663,-0.850942185,-6.249046802520752,-6.579104900360107,-5.850211143493652,-6.560532569885254,-6.303859233856201 -1141,1141,A84D,0.016112201,-0.011320308999999999,0.028974468,0.037160109,-0.005715479,0.039745903,0.04070601,-0.008481609000000001,0.064345175,-0.031119888,0.008479271,0.060688494,-0.002739558,0.025768941,0.048551277000000004,-0.051240785,0.039809827,1.339562443,2.506177327,-3.6145935710000003,-2.358720139,-4.024892052,-4.492796173,-3.458454063,-3.738105431,-4.706804491000001,-1.775913975,-7.061146259307861,-7.31626033782959,-7.3410725593566895,-7.594499588012695,-8.044658660888672 -1142,1142,A84G,-0.008743023,-0.009919053,0.030297802999999998,0.010604095,-0.024581986,0.028956292,-0.014665586999999999,-0.002820458,-0.000531044,-0.002879435,-0.01695867,0.055663412999999995,0.004932192,-0.0055866859999999996,0.026794875,-0.027716017000000003,-0.021447955,1.184913061,2.456388285,-4.111107758999999,-2.6916045989999997,-4.808729004,-3.9647619780000003,-4.574019615,-4.5164235989999995,-5.287182914,-2.908204527,-6.86687707901001,-7.349551200866699,-7.44732666015625,-7.215400218963623,-7.687894344329834 -1143,1143,A84F,0.026800011000000002,0.008507744,0.04761136,0.014222851000000002,-0.186143212,0.056387382,0.033728957000000004,0.019871065,-0.008342516999999999,-0.017702443,0.03471793,0.048546125999999995,0.046676592999999995,-0.008500129,0.036945831,-0.21460044600000003,-0.157685977,1.416943555,2.098464661,-9.742337298999999,-6.886958412,-11.34148347,-10.06908424,-9.157087151,-11.25707323,-9.386055015,-8.771873457,-8.898279190063477,-10.228800773620605,-10.385364532470703,-9.701017379760742,-10.47028923034668 -1144,1144,A84I,0.037544266,0.031125492999999997,0.04637431400000001,0.030265532999999997,-0.013374836999999999,0.047745805999999995,0.017706331999999998,0.0573822,-0.030804663,0.033809134,0.028441851,0.058137827999999996,0.0346108,0.046066204000000006,0.014464862,-0.036157277,0.009407603,1.3819341680000001,2.678932206,-5.435155227999999,-3.36135144,-6.857830795,-5.092120918,-5.079789482,-6.784683502000001,-5.840283682000001,-3.5869814769999997,-8.210189819335938,-8.01861572265625,-7.099498748779297,-8.483685493469238,-8.447209358215332 -1145,1145,A84H,0.02273299,-0.005790821999999999,0.03668153,0.027081882,-0.000873553,0.004769037,-0.005714326,0.051180305,0.17770935399999999,0.024025791,-0.035607435,0.071683226,0.0016798339999999998,0.028945254,0.02521851,0.012058979,-0.013806085,1.543610422,3.106887046,-4.2702645939999995,-2.596909622,-5.107809273,-4.822845543,-4.561553925,-4.262204605,-5.161538318,-2.412939445,-6.565574645996094,-7.00307559967041,-7.134124755859375,-7.300354480743408,-6.566632270812988 -1146,1146,A84K,0.058455078,0.033255941000000004,0.07042799200000001,0.046430810999999995,0.027428182000000002,0.045141214000000006,0.045570164,0.071339992,-0.04372667400000001,0.044180667,0.022331214,0.092782456,0.048073528,0.056995298,0.035866324,0.025310252000000002,0.029546112000000003,1.034682754,2.555993639,-1.795460637,-0.88035511,-2.3164036869999998,-2.77899839,-2.25850515,-0.7430408479999999,-3.615480533,-0.7142193809999999,-5.025532245635986,-4.642299652099609,-3.8924155235290527,-5.5899882316589355,-3.7414910793304443 -1147,1147,A84M,0.02976156,0.002512851,0.046822681,0.023207642,-0.009573927,0.023854438999999998,0.026701981,0.032821138,0.018908324,-0.004839512,0.009865213000000001,0.028389658999999998,0.065255703,0.009703195999999999,0.036712088,-0.032788796,0.013640943,1.327300781,2.555607532,-6.478755859,-4.909011314,-8.184231102,-6.7960189589999995,-6.025733703999999,-6.4787842179999995,-6.688696472,-4.630778688,-7.223364353179932,-7.70780611038208,-7.270388126373291,-8.034709930419922,-7.062483310699463 -1148,1148,A84L,0.038657231,-0.0023488470000000003,0.053646807000000005,0.039411722,0.005085066,0.03857616,0.039297025,0.038017436,-0.028634597999999997,-0.01397469,0.009276996,0.040510951,0.06678266299999999,0.02497658,0.053846862999999995,-0.035698872,0.045869003,1.153938629,2.386782976,-5.273322597,-2.5716356119999997,-7.31011277,-5.772872871000001,-4.77225367,-5.93973806,-5.483421738,-2.178117913,-6.082027435302734,-6.818791389465332,-5.608371734619141,-6.853315830230713,-6.453079700469971 -1149,1149,A84N,0.06960399,0.034260571000000004,0.060363623,0.042273860999999996,0.037337985,0.061537134,0.076766182,0.062441798,-0.002620552,0.008452504,0.060068637,0.074324158,0.046403087,0.031963674,0.052584047,0.0035543740000000003,0.071121596,1.188288169,2.630149916,-2.8483835330000002,-2.115461937,-3.180437172,-3.194479065,-3.2858681410000004,-2.465671349,-4.767754692,-2.053582197,-5.139152526855469,-5.30567741394043,-5.836411476135254,-5.938933849334717,-6.119219779968262 -1150,1150,A84Q,0.047819917,0.058947877999999995,0.061433796,0.042319706,0.02005532,0.02742766,0.043594573,0.05204526,-0.046997672000000004,0.11274442800000001,0.005151328,0.070788821,0.05207877,0.037261067,0.047378344,0.022019207000000002,0.018091432,1.179151542,2.7240743039999997,-1.892163843,-0.619951653,-2.269922989,-2.7536371839999996,-2.360191345,-1.457116043,-3.3266108180000002,-0.791436696,-4.573575973510742,-4.711268424987793,-3.6924030780792236,-5.484407424926758,-3.6867547035217285 -1151,1151,A84P,-0.023263699,-0.013467298,-0.038051462,-1.563208104,-2.3601396180000003,0.092560235,-0.006461781,-0.040065616,0.067347066,-0.014019996000000002,-0.012914598999999999,0.005180692,-0.081283615,-1.398879891,-1.727536317,-2.204493871,-2.515785365,0.732938674,0.7149348940000001,-6.613263507,-5.107170921,-7.407126511,-7.281639671000001,-6.185678345,-7.084702087,-6.952731985,-4.879590906000001,-12.512928009033203,-12.811132431030273,-12.238500595092773,-12.971646308898926,-12.595382690429688 -1152,1152,A84S,0.029124966000000002,-0.004853581,0.034941138,0.02733236,0.012671526,0.021777934,0.021262958,0.036986973,-0.034898738,-0.033794688999999996,0.024087527,0.049350273,0.020532002,0.013592873,0.041071847,-0.012541746000000001,0.037884798,1.2885980559999999,2.6875951510000005,-2.03665835,-1.270673996,-2.037686455,-2.070626808,-2.3747157519999997,-2.429588737,-3.963402228,-1.544413971,-5.032944202423096,-5.240077972412109,-5.107530117034912,-5.165668487548828,-5.765264511108398 -1153,1153,A84R,0.059796684,0.014987,0.055523469000000006,0.041662099,0.016879106,0.002524427,0.056410352999999996,0.06318301400000001,-0.039179667,0.008457592,0.021516407999999997,0.045330199,0.06571673900000001,0.018296946,0.06502725200000001,-0.01313214,0.046890352,1.114053806,2.46394564,-2.201205472,-0.7779428629999999,-3.0564672089999996,-2.9899081730000003,-2.273754372,-1.9079547419999998,-4.059759785,-0.383069447,-4.534465789794922,-5.7940897941589355,-4.62114143371582,-6.272636890411377,-4.479321002960205 -1154,1154,A84T,0.012935651999999999,-0.0026622,0.042518823,0.020981884,-0.01452706,0.053745617999999995,0.020620331999999998,0.005250972,0.015256666,-0.001601442,-0.0037229570000000003,0.035022439,0.050015206,0.014545467,0.027418301000000003,-0.039540333,0.010486213999999999,1.31932374,2.550777895,-2.436505905,-1.884270805,-2.362613411,-2.192047783,-2.674392639,-3.0692048869999997,-4.509298514,-1.840575445,-6.287845134735107,-6.046607494354248,-6.130491733551025,-6.856927394866943,-6.335842609405518 -1155,1155,A84W,0.013481052,0.027025544,0.041726408,0.037018367,-0.395755631,0.053858027,0.012731373,0.014230731000000002,-0.007935481999999999,0.035125746,0.018925341000000002,0.07278689299999999,0.010665923,0.070434078,0.0036026559999999997,-0.275654079,-0.5158571829999999,1.383502477,2.0215677469999997,-8.660062907,-6.412333167999999,-10.0998651,-8.99853418,-8.238330864,-9.551251228,-8.345260108,-6.622117527,-10.716666221618652,-11.273042678833008,-11.869595527648926,-11.794390678405762,-10.687877655029297 -1156,1156,A84V,0.020949721,0.0029622,0.007884575999999999,0.041511479,-0.020480268,0.065518442,0.00844634,0.033453101,0.015432886000000002,-0.013781203,0.019705602,0.029632972,-0.013863821,0.033212726,0.049810230999999996,-0.044137489,0.003176954,1.368030563,2.636979071,-4.840387595,-3.3959091189999997,-6.2883246,-4.171610519,-4.577073227,-5.769020508,-5.2737693,-3.5126119439999997,-7.74352502822876,-7.395386219024658,-7.1038055419921875,-7.6419358253479,-7.257613658905029 -1157,1157,A84Y,0.008516349,-0.0033431809999999998,-0.005425017,0.031171412000000003,-0.150514537,0.081910934,0.002192823,0.014839875,-0.038725146,-0.004800118,-0.001886244,0.028699593,-0.039549627000000004,0.010116712,0.052226111,-0.161804396,-0.139224677,1.448061782,2.238368622,-7.326366263,-4.669548775,-8.978424103,-7.507943794,-6.907978554,-8.567936089,-6.623514561,-4.225877116,-9.122379302978516,-10.504866600036621,-10.566519737243652,-10.181381225585938,-10.010622024536133 -1158,1158,G85A,-0.045494527,0.005673465,-0.004675723,-0.02002461,-0.134062149,0.011551997,-0.057938535,-0.033050519,0.055082083,-0.012872828999999999,0.024219759,-0.00371771,-0.005633735,-0.045680644000000006,0.005631424,-0.114959144,-0.153165153,1.23583949,2.142959763,-4.970801604,-4.923278427,-5.277532082,-6.17622168,-4.890285637,-3.586690193,-4.815866686000001,-4.215600771,-8.726053237915039,-9.578865051269531,-7.944979667663574,-8.706321716308594,-8.582961082458496 -1159,1159,G85C,-0.06762691900000001,0.016737244,-0.038478899999999996,-0.045145997,-1.4026250319999998,0.05800635,-0.075561441,-0.059692395999999995,0.190041181,-0.042646283,0.07612077,-0.019954096,-0.057003702999999996,-0.035624324,-0.054667669,-1.238052925,-1.5671971390000001,0.842010044,1.351381989,-7.5835370410000005,-6.810353957999999,-7.899863777,-8.976203177999999,-6.612146507,-7.619117782999999,-7.462001985,-6.134910324,-10.706183433532715,-11.199451446533203,-11.220767974853516,-11.102348327636719,-13.181614875793457 -1160,1160,G85E,-0.04912052,0.026280801,-0.007104728,-0.023936673999999998,-0.088473564,0.026864835,-0.056829407,-0.041411632000000004,0.14473655300000002,0.003427628,0.049133973,-0.026336731000000002,0.012127276000000001,-0.036793574,-0.011079773000000001,-0.114638789,-0.062308338,1.5054119730000002,2.394398974,-5.281595103,-5.09466008,-4.939381897,-7.1866980289999995,-4.05875148,-5.128484032,-4.8778048730000005,-3.20831146,-8.661935806274414,-8.836371421813965,-7.8386688232421875,-9.093626022338867,-8.255459785461426 -1161,1161,G85D,-0.056540105,-0.063261732,-0.04905168099999999,-0.04509012900000001,-0.106921018,0.038850182999999996,-0.030706575,-0.082373634,0.23215111600000002,-0.005545258000000001,-0.120978205,-0.007314593,-0.090788768,-0.048724085,-0.041456172,-0.087078791,-0.126763244,1.3641896409999998,2.335292185,-5.277745706,-4.498427521,-4.515184608,-7.504985405,-3.9249017489999996,-5.9452292479999995,-4.729393883,-2.479800896,-8.723738670349121,-8.830599784851074,-8.365219116210938,-9.506153106689453,-8.347846984863281 -1162,1162,G85F,0.029152246,0.038798721,0.011852151000000002,-0.0037735959999999997,-0.6155449789999999,0.010589737,0.002068819,0.056235673,0.067676152,0.018356261000000002,0.05924118,0.018218181,0.00548612,-0.015916751,0.00836956,-0.559543385,-0.671546573,0.979244007,1.5190843569999999,-9.860517162,-8.76168885,-10.76290843,-11.19643118,-8.416792053,-10.16476529,-9.186646766,-10.17688797,-12.119178771972656,-13.200675010681152,-11.978466033935547,-13.029682159423828,-12.789134979248047 -1163,1163,G85I,0.015318501000000002,0.035779289,-0.001290188,-0.199866711,-1.5315992859999998,0.07454902599999999,0.025537028,0.005099973,0.171981775,-0.05664302,0.128201597,-0.051904676,0.04932430000000001,-0.170623343,-0.229110079,-1.6431328040000002,-1.4200657680000002,1.1407864620000001,1.3526396969999999,-9.193322557,-7.937546707,-10.29889357,-10.513065800000001,-7.5264435039999995,-9.6906632,-7.680020476,-7.08504776,-13.360193252563477,-14.782293319702148,-12.01072883605957,-13.240745544433594,-13.819421768188477 -1164,1164,G85H,-0.010170774,-0.010804266000000002,-0.046503315,-0.039984248,-0.051679095999999994,-0.069309183,-0.063053687,0.04271214,0.125281636,-0.017018927,-0.004589604000000001,-0.025378592999999998,-0.067628037,-0.064382016,-0.015586478999999999,-0.057251171,-0.046107021,1.405395516,2.450834117,-5.7648331960000005,-5.03192424,-6.55672007,-6.691097038,-4.786579185,-5.757845444,-5.058254541,-3.9799092239999996,-9.576888084411621,-8.86719799041748,-8.919852256774902,-9.263219833374023,-7.6180338859558105 -1165,1165,G85K,-0.006298399999999999,0.03045023,-0.0008542310000000001,-0.038739607,-0.033350538,-0.021819678,-0.021804072,0.009207271999999999,0.090010349,-0.013245934,0.074146394,-0.020786218000000002,0.019077756,-0.047550675,-0.029928537999999998,-0.061938945,-0.00476213,1.2356145920000001,2.3162053119999997,-3.638664856,-2.82105101,-3.845787033,-4.947062103,-3.0862709660000003,-3.493153168,-3.787463349,-2.9761541,-7.909027099609375,-7.312166213989258,-7.413664817810059,-7.783761024475098,-6.787364482879639 -1166,1166,G85M,-0.029473892,0.031363942,-0.014045542,-0.024594839,-0.18668588100000003,0.025720771,-0.058357623,-0.000590161,0.10503039199999999,-0.013784979,0.076512862,-0.002833688,-0.025257396,-0.046899424,-0.002290254,-0.16120553099999999,-0.212166231,1.469862864,2.251062208,-8.223594408,-7.0570102310000005,-9.171116394,-9.619933357,-6.936675888,-8.333236167999999,-7.316257679,-6.587449024,-11.363680839538574,-12.321903228759766,-10.46584415435791,-11.060428619384766,-11.399227142333984 -1167,1167,G85L,-0.057280909000000005,0.018847409,-0.00990461,-0.031534822000000004,-0.424891033,0.055974327000000004,-0.070847705,-0.043714113,0.123635323,-0.007331888000000001,0.045026706,-0.0031839990000000003,-0.016625221000000003,-0.04238674,-0.020682904,-0.374399593,-0.47538247200000006,1.315392613,1.814269891,-7.740498155,-6.5124631420000005,-8.906674469,-8.98989608,-6.202539268,-8.090917816000001,-6.671122375,-5.9947101,-10.99248218536377,-11.954405784606934,-9.520304679870605,-10.76107406616211,-11.342375755310059 -1168,1168,G85N,-0.006804173,-0.038492386,-0.023017627000000002,-0.013579932,-0.07667470900000001,-0.006625206999999999,-0.03638781,0.022779464,0.237828249,-0.040351158,-0.036633612999999995,-0.032603912,-0.013431341000000001,-0.073011449,0.045851585,-0.106606295,-0.046743123,1.363723155,2.254357076,-4.365600484,-3.910720848,-4.397990288,-5.8779802860000006,-3.8719850389999997,-3.769325958,-4.564714529,-3.0329104360000003,-7.554293155670166,-7.87055778503418,-7.98341703414917,-8.019691467285156,-7.195732116699219 -1169,1169,G85Q,-0.023386707000000003,0.011642429,0.0049370379999999995,-0.017618004,-0.025383443,-0.008512774,-0.052286955,0.005513542,0.101471158,-0.025219187999999997,0.048504045,0.015462004,-0.005587929,-0.046284875999999996,0.011048869,-0.05312828,0.002361395,1.268116262,2.3377582390000002,-5.184446939,-4.534344376,-6.053871704,-6.138254997000001,-4.353173233,-4.842590385,-4.537664691,-3.430987942,-8.715047836303711,-8.39657974243164,-7.9377827644348145,-8.412347793579102,-7.344367027282715 -1170,1170,G85P,-0.076432019,-0.073465251,-1.355532061,-2.145045111,-2.908875342,0.015316943000000001,-0.066059386,-0.086804652,0.167450749,-0.016924125,-0.130006376,-1.2721139,-1.438950221,-2.0237441730000003,-2.266346048,-2.751144509,-3.066606175,2.366541,0.928534959,-8.436407391,-7.892549788999999,-8.897169891,-9.590136047,-7.730106972000001,-8.072074257,-7.93289289,-7.08504787,-15.229984283447266,-17.220199584960938,-13.010181427001953,-13.374334335327148,-14.872783660888672 -1171,1171,G85S,-0.033985428,-0.001685295,-0.031968005,-0.027776754,-0.164970784,-0.011824446,-0.048477234,-0.019493622,0.09057981400000001,-0.029448343999999998,0.026077755,-0.029067772999999998,-0.034868236000000004,-0.043249126,-0.012304381999999999,-0.17218437399999997,-0.15775719300000002,1.4341729269999999,2.191746645,-5.244926497,-5.034703766,-5.3297528530000005,-6.3229169160000005,-5.505439095,-4.031819855,-5.4030092210000005,-4.03245545,-8.642772674560547,-9.51210880279541,-8.434335708618164,-8.73011302947998,-8.31340503692627 -1172,1172,G85R,-0.050108415999999996,0.0053667359999999996,-0.024332338,-0.031185887000000002,-0.1023798,0.014703173,-0.055652151,-0.04456468,0.119362392,-0.005105665,0.015839137,-0.011814426999999999,-0.036850249,-0.026155582,-0.036216192,-0.10063032599999999,-0.10412927400000001,1.453623291,2.403376724,-4.997319452,-4.016695465,-6.023374649,-5.952515419,-3.6204244919999997,-5.373587235,-4.878773333,-3.451941563,-8.59260368347168,-8.534761428833008,-8.084981918334961,-8.571537971496582,-7.623658180236816 -1173,1173,G85T,-0.08305449200000001,-0.022286671,-0.029338822999999997,-0.051329989000000006,-1.2822142440000002,0.049189183,-0.08523439,-0.080874593,0.147091687,-0.02350772,-0.021065622000000003,-0.009601425,-0.049076220999999996,-0.042263032,-0.060396945,-1.1402891609999999,-1.4241393269999998,0.659829284,1.339298508,-6.297128513,-5.6832192,-6.95415818,-7.038778946,-5.765471893,-6.044014343,-5.786376892000001,-4.814866976999999,-11.227405548095703,-12.285604476928711,-9.771285057067871,-10.544637680053711,-11.219419479370117 -1174,1174,G85W,-0.048077875,0.034556368,-0.007826867,-0.0071251380000000005,-1.596722025,0.08544188800000001,-0.042624052,-0.053531697,0.131527655,-0.00306906,0.072181795,-0.0024782370000000003,-0.013175497,-0.009351986999999999,-0.004898289,-1.581319765,-1.612124285,0.670212756,1.318099578,-9.222419188,-7.8886992110000005,-9.379488853,-10.76473759,-8.083603652999999,-9.995566627999999,-8.144355623,-7.748490007999999,-12.793449401855469,-14.3275146484375,-12.920419692993164,-13.394214630126953,-12.4569091796875 -1175,1175,G85V,-0.061125331,-0.002129729,-0.02687701,-0.044892332,-1.542004165,0.021949445,-0.053576684000000006,-0.068673977,0.08325443,-0.029124131,0.024864674,-0.015270648999999999,-0.03848337,-0.021715933,-0.068068731,-1.607405625,-1.476602705,0.7692721840000001,1.31963984,-8.010738562,-6.866942184,-8.940439078999999,-9.345921882999999,-7.211634285,-7.688755379,-6.685152382,-5.403878074,-11.759191513061523,-13.044387817382812,-10.577762603759766,-11.577428817749023,-11.758620262145996 -1176,1176,G85Y,-0.04462753,-0.022910233999999998,0.001453778,-0.05057197099999999,-0.7941742559999999,-0.026840877000000003,-0.066831562,-0.022423497999999997,0.011931118000000001,-0.040263047,-0.00555742,0.014483895,-0.011576339,-0.07711136,-0.024032581,-0.545222757,-1.043125754,1.6894682109999999,1.9506647419999998,-8.647571689,-7.601936867,-9.282961617,-9.912909897,-7.23850341,-9.201546654,-7.2866114379999996,-6.688132427,-12.33765983581543,-12.72319221496582,-11.90003776550293,-12.981425285339355,-11.570596694946289 -1177,1177,Q86A,0.010585303,-0.054818768,-0.03879968,-0.008917203,-0.031346184,0.014052771,0.012010375,0.009160231,-0.018123461,-0.054414619000000004,-0.055222917,-0.027080872000000002,-0.050518487,-0.013683558,-0.004150847,0.010314100999999999,-0.073006469,1.3223779759999998,2.673405999,-2.752754758,-2.89783725,-2.209007782,-2.4250490719999998,-3.4945196689999998,-2.7373600160000002,-3.1006541480000003,-0.468632063,-4.562997817993164,-5.64650821685791,-6.167943954467773,-7.519998550415039,-6.972998142242432 -1178,1178,Q86C,0.056980234000000005,0.005079040999999999,-0.053058544000000006,-0.060903585999999996,-0.321765932,0.054265308,0.050612104000000005,0.063348364,-0.050647145,-0.031272522999999997,0.041430603999999996,-0.124991973,0.018874886,-0.092022596,-0.029784576,-0.031664545,-0.6118673179999999,1.264408989,2.364101861,-6.845409148,-7.045994117999999,-6.897099387999999,-6.254165146,-7.261225014,-6.768562072999999,-6.431794699,-3.3686861219999997,-8.558615684509277,-11.584551811218262,-11.331101417541504,-10.536308288574219,-11.817755699157715 -1179,1179,Q86E,0.014009057,-0.02905182,-0.033168435,-0.027986847999999998,-0.036396335,-0.03514691,-0.002393708,0.030411821000000002,-0.045185489,-0.037197226,-0.020906413000000002,-0.058880744000000006,-0.0074561259999999996,-0.048213451,-0.007760245,-0.003490753,-0.06930191599999999,1.25165709,2.497870252,-0.56897356,-0.564854874,-1.385282455,-0.21519980600000002,-0.818287918,0.138757256,-2.5488115280000003,0.7992980909999999,-4.0107011795043945,-4.023436546325684,-4.542050838470459,-6.1174845695495605,-5.778601169586182 -1180,1180,Q86D,0.012097256,0.008241078,-0.016288709,0.028376834,0.009897319,-0.03610019,-0.011804887,0.035999397999999995,0.06556053099999999,0.066817638,-0.050335482,0.015636893,-0.04821431,0.03915387,0.017599798,0.127961722,-0.108167085,1.137663383,3.1531209639999997,-2.8723349560000004,-3.4580397030000003,-2.707114525,-2.097564301,-3.8369823760000004,-2.261973877,-2.20527596,-0.41184812299999995,-5.953160762786865,-6.352110862731934,-6.588660717010498,-8.454322814941406,-7.925100326538086 -1181,1181,Q86G,0.026653938999999998,-0.010489343,-0.031594417,0.01091036,-0.049850188,-0.004195942,0.014408697,0.038899181,-0.002439801,-0.0036048240000000004,-0.017373862,-0.019889041,-0.043299792000000004,0.005985506999999999,0.015835213,0.049427719,-0.149128095,1.078703398,2.790278556,-4.7233752980000006,-5.032029518,-4.271832893,-4.18420089,-5.016516907,-5.11229628,-4.693500868,-0.25002365,-6.720799446105957,-8.154394149780273,-7.695434093475342,-8.730910301208496,-7.544762134552002 -1182,1182,Q86F,0.066157602,0.08669586300000001,0.095739492,0.101461242,0.120341129,-0.048221266,0.106588026,0.025727178,0.245639815,0.244898795,-0.071507069,0.23490822,-0.043429237,0.19507813300000001,0.00784435,0.287094218,-0.046411960999999995,0.9165512920000001,3.106668886,-7.558686885,-7.259739692999999,-7.606846161,-6.980115196,-8.072054085,-7.8746792910000005,-6.490177642000001,-3.848821304,-7.617251396179199,-9.203840255737305,-9.156810760498047,-10.343856811523438,-10.067523956298828 -1183,1183,Q86I,0.010187368,0.012985412,-0.000515842,-0.006363107,-0.039301078999999996,-0.090305139,0.008784131,0.011590605,0.0135243,0.026759105,-0.000788282,0.0051571640000000005,-0.006188848,-0.009526659,-0.0031995540000000003,0.003975811,-0.082577969,1.278431235,2.60751668,-4.15654048,-3.8754557189999996,-3.467368057,-4.636154121000001,-4.3235775069999995,-4.480146996,-3.869006896,-1.102176284,-4.853119373321533,-7.018083572387695,-7.0408430099487305,-8.212607383728027,-8.254910469055176 -1184,1184,Q86H,-0.0069312290000000006,-0.018887575,0.007868559,0.041869927,-0.014527212,-0.019111457,-0.011217685,-0.002644772,0.017644317,0.011237216000000001,-0.049012365,0.041166414,-0.025429297000000003,0.043027765999999995,0.040712087,0.060909713,-0.089964136,1.027434188,2.893681162,-3.9526721310000004,-4.076336052,-4.169997749,-3.417893654,-3.8111143189999996,-4.288018883,-4.042713633,-1.746444251,-6.174134731292725,-6.567882537841797,-6.4927849769592285,-6.364208221435547,-5.630514144897461 -1185,1185,Q86K,0.023142166000000002,-0.038368765,-0.019516181,-0.035926078,-0.009362488,-0.020474255,0.027832027000000002,0.018452304,-0.017611261,-0.055638111,-0.021099418999999998,-0.025556093999999998,-0.013476267,-0.051049198,-0.020802958,0.036046664,-0.054771639000000004,1.1765857709999998,2.5441896880000003,-1.062164688,-0.973031685,-0.557940353,-1.178966225,-1.218440567,-1.382444611,-2.244969801,0.920795435,-2.9997406005859375,-5.08987283706665,-4.469203948974609,-4.5474853515625,-3.0339341163635254 -1186,1186,Q86M,0.021486086,-0.053107154000000004,-0.019208793000000002,-0.039024577000000005,-0.015556395,-0.018302093000000002,0.010439200000000001,0.032532972,-0.023963535,-0.062761779,-0.043452528,-0.02808196,-0.010335626,-0.07649837400000001,-0.00155078,0.033250557,-0.064363346,1.182158972,2.665250158,-4.815128294,-4.813691818,-4.605895782,-5.072904900000001,-4.353488983,-5.229659988,-5.070485437,-1.9910955240000001,-5.4270830154418945,-6.231539726257324,-7.582769393920898,-8.35565185546875,-7.932753086090088 -1187,1187,Q86L,0.03601063,-0.065855974,-0.057251882999999996,-0.053047971,-0.029438376000000002,-0.048022767,-0.004101392,0.076122652,-0.11901161800000001,-0.11632429,-0.015387656999999999,-0.110540916,-0.003962849,-0.128861518,0.022765576000000003,-0.041051158,-0.017825594,1.424189411,2.419766583,-2.887847513,-3.392307442,-2.124766884,-2.8261766130000003,-2.831946152,-3.2640404739999997,-3.028094817,-0.208691955,-3.7638022899627686,-6.216487884521484,-5.940772533416748,-7.151774883270264,-6.5807952880859375 -1188,1188,Q86N,0.052813944,0.014941383999999999,0.047311009,0.031959916,0.014918118999999999,0.010668411000000001,0.055055438,0.050572449000000005,0.065201932,0.051709553,-0.021826785,0.082065431,0.012556586000000002,0.05551403,0.008405801999999999,0.09688875,-0.06705251200000001,1.671448915,3.643209181,-3.4242748830000003,-2.729698265,-2.773420929,-4.442790962,-3.748093155,-3.4273711010000003,-5.08503115,-0.732273627,-5.709564685821533,-6.359318733215332,-6.543195724487305,-7.286394119262695,-5.741379261016846 -1189,1189,Q86P,-0.009947522,-0.044456859,-0.027340155,-0.251576877,-1.368783659,0.014785847,-0.002880681,-0.017014361999999998,0.008951367,-0.005580671999999999,-0.083333046,-0.031291486,-0.023388824,0.053070648,-0.556224401,-0.944686425,-1.7928808930000002,0.649451662,1.3542210430000001,-5.822575835,-6.75347406,-4.318740707,-4.664931084,-5.837925643999999,-7.537807677999999,-4.91839368,-0.384292676,-11.985710144042969,-13.231937408447266,-11.518775939941406,-12.353840827941895,-13.616053581237793 -1190,1190,Q86S,0.034026422,0.001047659,0.012151944,0.00781268,0.01643971,-0.025380116,0.011065115,0.056987729,0.051857787999999995,0.037775495,-0.035680178,0.023041511,0.001262377,0.021092222999999997,-0.005466864,0.08724432900000001,-0.054364909,1.07861636,2.828609385,-2.5815441480000003,-2.332343132,-2.563018623,-2.588738853,-2.665047859,-2.758572273,-3.6217616510000004,-0.856813655,-5.687600135803223,-6.667412281036377,-6.622271537780762,-7.999368190765381,-7.277405738830566 -1191,1191,Q86R,0.024864589,0.015786256999999998,-0.0067394709999999995,0.015121835,0.007385750999999999,-0.011459622,0.010708428999999998,0.039020748,-0.003486922,0.012550391000000001,0.019022122,-0.005969584,-0.0075093569999999995,0.024096744,0.006146925,0.054593341,-0.039821839,1.543610422,3.106887046,-2.639448869,-3.068323784,-2.20178212,-2.565021729,-2.905449806,-2.4566669080000003,-3.379767771,0.608657632,-4.565828800201416,-6.727052688598633,-5.675286769866943,-5.627190589904785,-5.075006484985352 -1192,1192,Q86T,0.014450946000000001,0.01220451,0.034871917,0.040506007000000004,0.065980786,0.0008059230000000001,0.004099858,0.024802032999999998,0.11536854099999999,0.063387254,-0.038978235,0.088499541,-0.018755707,0.066634553,0.01437746,0.171481181,-0.03951961,0.983262629,3.008525655,-2.407377893,-1.9517168880000002,-2.712924957,-2.1961353530000003,-2.540507866,-2.635604401,-3.515539468,-0.21152016699999998,-4.647933006286621,-6.09106969833374,-6.008513927459717,-7.671577453613281,-6.409374237060547 -1193,1193,Q86W,0.01317419,-0.016584198,0.005834941,0.024550323,-0.024832316,-0.02360262,-0.019715075,0.046063455,0.044256397999999995,-0.002153,-0.031015395,0.032596661,-0.02092678,0.042155534,0.006945112,0.076477848,-0.12614248,1.223759613,2.920356167,-7.4031231,-7.381430695,-6.755933402999999,-7.144129486000001,-7.723874313,-8.010247604,-6.551369403,-3.486995392,-9.770580291748047,-11.431488037109375,-11.053243637084961,-11.506603240966797,-11.356280326843262 -1194,1194,Q86V,0.02515177,-0.0053272169999999995,-0.000314841,0.030028581000000002,-0.0022315029999999997,-0.009557375,0.009316399,0.04098714,0.036916186000000004,0.012136303999999999,-0.022790737999999998,0.013956689,-0.014586371,0.048423533,0.011633629,0.071809238,-0.076272243,1.025394224,2.831263812,-3.6672035480000003,-3.859326523,-3.046392967,-3.701760948,-4.2795098110000005,-3.4490274889999997,-4.401748111,-1.215943085,-4.568948745727539,-6.913870334625244,-6.224447250366211,-7.771442890167236,-7.831760406494141 -1195,1195,Q86Y,0.01708332,0.064060429,0.047005165,0.075821362,0.037876743,0.000714221,-0.009313247,0.043479885999999995,0.138033242,0.14033513,-0.012214273000000001,0.095895309,-0.001884979,0.168180255,-0.016537531,0.187855542,-0.11210205699999999,1.045878245,3.0479339939999996,-7.934539603999999,-7.373708221,-8.520482262,-7.217358536,-8.229860832,-8.33128817,-6.559336351000001,-3.765829055,-8.05401611328125,-9.560874938964844,-8.798713684082031,-9.681341171264648,-9.576224327087402 -1196,1196,E87A,0.054883243,0.12666019,0.105446796,0.165353435,-1.004393455,0.09127443699999999,0.043757523,0.066008962,-0.030057431000000003,0.100095635,0.153224744,0.118890068,0.092003523,0.149254478,0.18145239100000002,-1.019388988,-0.989397922,0.495040119,1.333229684,-5.109531859,-4.305268311,-5.23374456,-4.89247052,-4.810771545,-6.305404358,-4.816919586,-0.7656808970000001,-9.536799430847168,-11.34072494506836,-11.044475555419922,-11.059736251831055,-11.832022666931152 -1197,1197,E87C,0.083543301,0.10035256199999999,0.021368566000000002,0.067982757,-1.900269091,0.028776696,0.07658446099999999,0.09050214,0.042291373,0.005791918,0.194913205,-0.06971994299999999,0.112457075,-0.005863935,0.141829449,-1.6070511580000002,-2.1934870230000003,1.0359992759999999,1.342789724,-10.38377314,-8.949290771,-9.342740807,-12.27384235,-10.2269903,-11.12600146,-8.052197658999999,-4.577108993,-13.777010917663574,-16.037891387939453,-15.940845489501953,-15.102773666381836,-16.66667938232422 -1198,1198,E87D,0.004289735,0.064088914,0.07981806799999999,0.094421639,-0.007214053000000001,0.11259021699999999,0.034187925,-0.025608456,0.037267668,0.029247439,0.09893038900000001,0.03391231,0.12572382599999998,0.049829205,0.13901407300000002,-0.014168354,-0.00025975099999999996,1.1005369090000001,2.511960346,-2.8954628369999997,-2.146538925,-3.6555587010000004,-2.437914207,-2.7525839839999997,-3.484718369,-3.751197849,-1.225791238,-7.3720245361328125,-7.783140659332275,-7.844381332397461,-8.409400939941406,-7.6983642578125 -1199,1199,E87G,0.007300494,0.060079602,0.060965484,-0.326062156,-1.6691985459999998,0.059615249,0.025781863,-0.011180875,0.06534432700000001,0.030266537000000003,0.089892666,0.0011940780000000001,0.120736889,-0.174661995,-0.477462316,-1.845745525,-1.4926515669999998,1.1154742290000002,1.3286593979999999,-6.9905730770000005,-7.133951424,-6.714056786,-6.373129494,-6.809387787,-7.9223398970000005,-4.821822611,-1.001575842,-12.081876754760742,-12.25458812713623,-13.28824234008789,-12.72337532043457,-11.63459587097168 -1200,1200,E87F,0.04914198,0.051986751,0.030353305,0.025354564,-0.292764895,-0.037387451,0.040665562,0.057618397,0.02263839,0.023670926000000002,0.080302575,-0.000231223,0.060937832000000004,0.03474228,0.015966847,-0.3001498,-0.28537999,1.171795417,1.80539168,-10.42113898,-8.35676181,-8.142894821,-13.76812366,-10.19023107,-11.64768356,-6.02970109,-0.818100575,-12.236391067504883,-16.19174575805664,-13.380547523498535,-13.842097282409668,-14.55792236328125 -1201,1201,E87I,0.09015658,0.029362755,0.05807796900000001,0.088589461,-0.022245569,0.021994293999999998,0.084436439,0.09587672,-0.005943343,-0.05938169099999999,0.1181072,-0.012130446000000001,0.128286383,0.008549631,0.16862929,-0.11780550199999999,0.073314364,1.220664437,2.171555293,-7.880623145,-6.2709324870000005,-6.537848251000001,-10.56727208,-6.8556091079999995,-9.171453796,-4.237217909,-0.143900103,-10.559893608093262,-14.021687507629395,-13.1758451461792,-12.356382369995117,-13.42745590209961 -1202,1202,E87H,0.047969527000000005,0.051791519,0.01778261,-0.61044485,-1.85153629,0.033351715,0.027467834,0.06847122,-0.039872791,-0.010254558,0.113837595,-0.079695121,0.11526034,-0.38122881,-0.839660889,-1.82429617,-1.878776409,1.5988553769999998,1.4024814209999998,-9.674004613,-8.425328293,-8.942672455,-11.23184199,-9.986610176000001,-9.783570152000001,-6.670784713,-3.444396428,-11.04983139038086,-13.966272354125977,-13.493758201599121,-12.346869468688965,-12.940503120422363 -1203,1203,E87K,0.013536526,0.096589505,-0.114560886,-1.587200639,-2.921329819,0.032324692,0.05148128,-0.024408229,-0.058274234,0.005664195,0.187514815,-0.102857567,-0.126264204,-1.529303485,-1.6450977930000001,-2.355935728,-3.48672391,0.9949777409999999,0.727246155,-7.3930514679999995,-6.133995041,-6.5615001070000005,-8.858368607000001,-7.2631259539999995,-8.148267632,-6.562240975,-2.8571117910000003,-12.432084083557129,-13.540532112121582,-13.694072723388672,-13.421844482421875,-12.937416076660156 -1204,1204,E87M,0.068093573,0.044894984000000006,0.057469567,0.069565683,-0.031613816,-0.015411293999999999,0.071053867,0.065133279,-0.0386477,0.012640753000000001,0.07714921400000001,-0.018105581000000003,0.133044714,0.010450761,0.128680604,-0.107415018,0.044187387,1.391309677,2.2738131630000002,-9.428950947999999,-7.223950737000001,-7.994802094,-12.29516174,-9.116459679,-10.51438049,-5.698153262999999,-2.433969709,-11.710643768310547,-14.271860122680664,-13.315095901489258,-12.300968170166016,-14.020376205444336 -1205,1205,E87L,0.081300597,0.022253731000000002,0.051457393,0.057691701,0.024209124,0.00381098,0.057405341,0.105195853,0.02846004,-0.032977778,0.077485239,0.000333529,0.102581257,0.028271808,0.087111593,-0.044644188,0.093062435,1.249082587,2.535920033,-7.294717725,-5.144012169,-6.407903602999999,-10.31099616,-6.403014519,-8.20766217,-4.6396456310000005,1.020998265,-10.350391387939453,-13.285000801086426,-12.147012710571289,-10.136831283569336,-12.210554122924805 -1206,1206,E87N,0.063549015,0.06770328,0.017724998999999998,-0.21772666899999998,-1.647481185,-0.009383554,0.057490999999999993,0.069607029,0.106891131,-0.019099434,0.154505994,-0.057378454,0.09282845199999999,-0.169533403,-0.265919935,-1.605613572,-1.6893487969999998,1.156391875,1.356477909,-8.230363306000001,-7.046586426,-8.141545563,-8.497781737999999,-8.546940002000001,-8.918962798999999,-6.09893344,-2.798043109,-11.321972846984863,-13.572876930236816,-12.977071762084961,-12.276895523071289,-12.909640312194824 -1207,1207,E87Q,0.089780716,0.07397422299999999,0.069884161,0.09814517,-1.1763081690000001,0.024947123999999998,0.088517434,0.09104399699999999,0.023194673,0.01691762,0.131030825,0.012606253999999999,0.127162067,0.055443081,0.140847258,-0.945349995,-1.4072663419999998,0.57939509,1.344701524,-5.660011464,-4.589993034,-5.380128426000001,-6.846401016000001,-5.0891289219999996,-6.394405922000001,-4.997555305,-2.506625759,-9.370762825012207,-10.368844985961914,-10.379364013671875,-9.475695610046387,-10.653793334960938 -1208,1208,E87P,0.039084006,0.054488055,-0.956548451,-1.5627208000000001,-2.483551041,0.021973349,0.03843972,0.039728292000000005,0.070408948,0.008229906,0.100746203,-0.9238370440000001,-0.9892598570000001,-1.6266904819999999,-1.4987511180000002,-2.44108827,-2.526013811,2.629287743,1.399998579,-9.59027757,-8.677533363,-9.330235435,-9.814526756,-9.190364647,-10.93872765,-6.823961098,-3.43171913,-13.48560619354248,-16.225614547729492,-15.528270721435547,-13.733773231506348,-15.269649505615234 -1209,1209,E87S,0.06732751,0.067180298,0.060565692000000004,0.027247136,-1.501669116,0.001751896,0.07447203299999999,0.060182985999999994,0.055011633,0.006869431999999999,0.127491164,-0.015493933,0.136625316,0.012197678,0.042296593,-1.52140875,-1.4819294809999999,0.825675763,1.328971383,-7.283317014,-6.682900093,-6.386404563999999,-7.136829201,-7.453746506,-8.756704704,-5.561082207,-1.748758662,-11.731710433959961,-13.730454444885254,-12.72298812866211,-12.797876358032227,-13.10324764251709 -1210,1210,E87R,0.052542878,0.07353947,-0.366531139,-1.502997067,-2.347803569,0.023305977000000002,0.040682587,0.064403168,-0.014786342,0.0060017230000000005,0.141077217,-0.312222053,-0.420840225,-1.4240238490000001,-1.581970285,-2.219398399,-2.476208739,2.537231438,1.557851047,-8.399886427,-7.9121610570000005,-7.530149826000001,-10.02127084,-8.311711922,-8.224138489,-6.400540251000001,-2.4388929040000003,-14.118025779724121,-15.868041038513184,-15.196542739868164,-14.314529418945312,-15.157657623291016 -1211,1211,E87T,0.05971782900000001,0.039958258999999996,0.074538331,0.046758354,-0.836128657,0.032342211,0.075538482,0.043897175,-0.010307766999999999,-0.00384867,0.083765188,0.049661355,0.099415306,0.060975779,0.032540928999999996,-0.738611421,-0.933645893,0.6041185379999999,1.3716709569999999,-7.627686154,-6.561831055,-7.017760857000001,-7.97037838,-7.8576400070000005,-8.730820473,-6.157600948,-2.21548644,-11.364203453063965,-13.208231925964355,-12.451064109802246,-12.43259334564209,-13.535433769226074 -1212,1212,E87W,0.048311982999999996,0.023110037000000003,0.022301841,-0.019671466000000002,-1.558419284,0.028381317000000003,0.051630113,0.044993853,0.040047417,-0.053412885,0.09963295800000001,-0.075100475,0.11970415699999999,-0.030112412999999998,-0.009230518,-1.668311959,-1.448526608,0.8184319090000001,1.320720501,-10.22769793,-7.922635277,-9.544488258,-14.2716673,-10.16517268,-9.234526146,-6.800990402999999,-2.376910186,-14.377113342285156,-16.3275089263916,-14.35456371307373,-14.706033706665039,-15.337226867675781 -1213,1213,E87V,0.081343989,0.044799356,0.07124581,0.065744569,-0.121958186,0.006778424,0.093958637,0.068729341,-0.036123532,-0.014817104,0.104415815,-0.013312306000000001,0.155803925,-0.011845022,0.14333416,-0.18467427600000003,-0.059242095,1.410200423,2.1405887569999997,-7.547631706000001,-6.13289547,-6.800055481,-10.09403954,-6.070106857000001,-8.64106118,-4.714836989,-0.965267733,-9.694601058959961,-12.556017875671387,-11.889422416687012,-11.352370262145996,-12.041720390319824 -1214,1214,E87Y,-0.005737366999999999,0.048880075999999995,0.024767855,0.050577964,-1.6328803809999999,-0.017911589,-0.02364949,0.012174756,0.089945711,0.028020657,0.069739495,-0.012671848000000001,0.062207557999999996,0.092845106,0.008310821,-1.6968949530000002,-1.5688658080000002,0.571382956,1.305859542,-10.94317333,-9.091825294,-9.292912636,-14.0056796,-10.8393398,-11.48610933,-6.652347876,-2.60354004,-12.751450538635254,-14.871664047241211,-13.75015926361084,-13.067931175231934,-13.560561180114746 -1215,1215,Q88A,0.032303935,-0.015409259,-0.027838091000000002,0.03415031,-0.00012030000000000001,-0.035432434,0.021772299,0.04283557,0.08842921699999999,0.010011893000000001,-0.040830411000000004,-0.017427823000000002,-0.038248358999999996,0.059166552000000004,0.009134068,0.014003903,-0.014244502,1.179757852,2.671965215,-3.386064307,-2.9231114430000003,-3.8684875560000003,-3.1783070139999996,-3.608939285,-3.3514762339999997,-4.225214262,0.020429423999999998,-5.247422218322754,-8.323755264282227,-7.394096374511719,-6.044867515563965,-7.844482421875 -1216,1216,Q88C,-0.040941677,-0.073486293,-0.073897993,-0.006473535,-0.273911584,0.100564635,-0.012769836000000001,-0.069113517,0.17245165,-0.08920131199999999,-0.057771274000000004,-0.047888032999999997,-0.099907952,-0.004574954,-0.008372115,-0.174510014,-0.373313154,1.51144349,2.3037967459999997,-8.662211247,-7.426382942,-8.959202347,-9.119914383,-8.223079483,-9.582477081,-7.824141543,-3.374428472,-8.063103675842285,-12.684874534606934,-11.476224899291992,-8.602217674255371,-12.851016998291016 -1217,1217,Q88E,0.033023935,0.029500985,0.025920347000000003,0.068388539,0.029576106,0.012693642,0.045343303,0.020704567,0.008080748,0.084087575,-0.025085606,0.051842054000000005,-1.36e-06,0.083649352,0.053127725,0.095611985,-0.036459774,1.1711857940000001,2.904147458,-3.439844473,-3.0875554660000004,-4.034687431,-3.5421092000000005,-3.4652821730000003,-3.069588097,-5.064371867,-0.23417693899999997,-4.532438278198242,-5.558737754821777,-5.9172210693359375,-5.75858211517334,-6.354755878448486 -1218,1218,Q88D,0.022855594,0.02456005,-0.005967556,0.043833308,0.077216808,0.004687223,0.035174185,0.010537002,-0.033243537999999996,0.088733325,-0.039613225,0.062220465,-0.074155576,0.07866574,0.009000876,0.082354001,0.072079615,1.1275347009999999,2.9638930930000003,-3.1212624819999997,-3.197294182,-2.8350370330000003,-3.698879784,-3.296120384,-2.578981026,-3.007647053,1.493232928,-3.5998289585113525,-8.619568824768066,-5.422232151031494,-6.013961315155029,-6.92673397064209 -1219,1219,Q88G,0.04705773,-0.009602994,0.00781269,0.049287055,-0.08186091200000001,0.030387405,0.052403639,0.041711821,0.055818228,0.010954182,-0.030160169,0.002488386,0.013136993999999999,0.067006761,0.031567347999999995,-0.07757111,-0.086150713,1.36154686,2.439371247,-6.182214547999999,-6.135061652999999,-5.507951858999999,-6.11832206,-6.757287346,-6.3924498210000005,-5.107864775,-0.526146201,-6.711156368255615,-10.85067081451416,-9.359567642211914,-8.002100944519043,-9.545289039611816 -1220,1220,Q88F,-0.051611405,-0.001272796,-0.026454515,0.035217414,-0.058579433,0.014499251999999999,-0.047894106,-0.055328704000000006,0.019886128,0.043048404000000005,-0.045593996,-0.057967322,0.005058293,0.072369524,-0.001934696,-0.028456465,-0.08870239999999999,1.260158852,2.6252634930000003,-9.651248251,-9.075219673,-10.56626432,-10.03139586,-9.146704521,-9.436656883,-5.807136816,-0.618946565,-7.428894996643066,-10.354101181030273,-10.076993942260742,-6.8227667808532715,-11.229706764221191 -1221,1221,Q88I,-0.047526307000000004,-0.083006531,-0.033625046,-0.022435838,-0.077210232,-0.019313336,-0.052195751,-0.042856862999999995,-0.00281786,-0.08216966,-0.083843402,0.025494395,-0.09274448699999999,0.0710031,-0.115874775,-0.012328306,-0.142092157,1.3478321180000001,2.8156437619999997,-7.753530051,-8.301544456,-8.267427223,-8.439984612,-6.282780869,-7.475913094,-6.210047906000001,-2.4796190240000002,-6.717046737670898,-10.118310928344727,-9.105785369873047,-7.209941864013672,-9.739734649658203 -1222,1222,Q88H,-0.024172062999999997,-0.038350228,-0.034833697999999996,0.027203092999999998,0.015802767,-0.013159448,-0.00938302,-0.038961106,0.035369685,-0.007643111,-0.069057345,-0.021554512,-0.048112882999999995,0.06510329200000001,-0.010697106000000001,0.020949181,0.010656352,1.129499537,2.631264114,-5.045301858999999,-3.6700244289999997,-6.3296175539999995,-5.682545189,-4.664576599,-4.8797455219999994,-5.725762321,-0.735535917,-5.773274898529053,-7.159539222717285,-5.8800554275512695,-5.4919209480285645,-7.268704414367676 -1223,1223,Q88K,0.046121101,0.00634495,0.00645875,0.074857676,0.094749771,-0.010936445,0.063996574,0.028245627000000002,-0.056047229000000004,0.075032865,-0.062342966,0.032622347999999995,-0.019704848,0.080969695,0.068745657,0.097505345,0.091994196,1.077968091,3.00832055,-2.6254966459999998,-1.9973394009999998,-2.664619804,-2.7105236660000003,-3.92558934,-1.829411018,-4.323068997,0.35741959,-5.0729522705078125,-7.022614479064941,-6.887504577636719,-4.599849700927734,-7.417211055755615 -1224,1224,Q88M,0.07591871900000001,-0.023065218999999998,0.023385101000000002,0.054149654000000005,-0.014628486000000001,0.077437063,0.079774818,0.07206261900000001,-0.000933716,0.003549997,-0.049680435,0.005469444,0.041300758,0.052563395,0.055735912,-0.016224552,-0.01303242,1.164682365,2.593359679,-7.143543128999999,-7.852766991,-7.307869286,-7.8255491710000005,-5.65929599,-7.072234207,-6.556273478,-3.074228615,-6.605043411254883,-8.522734642028809,-8.297932624816895,-6.9236159324646,-9.548898696899414 -1225,1225,Q88L,0.007272375,-0.01590591,-0.014248538,0.053277424000000004,-0.004543879,0.019477542,0.026567536,-0.012022786,0.060152979,0.009905035,-0.041716855,-0.0006582910000000001,-0.027838784,0.054556895,0.051997952,0.0036435879999999997,-0.012731346000000001,1.181087765,2.7348506130000003,-6.93084707,-8.129996185,-7.371398834,-6.923690071,-4.601644165,-7.627506096,-5.094279447,0.177777375,-5.514416694641113,-7.402463436126709,-7.86134147644043,-6.493838787078857,-8.287942886352539 -1226,1226,Q88N,0.023390104,0.062870117,0.018556473,0.053838135999999995,0.027462082000000002,0.015104343000000001,0.021971547,0.02480866,0.11771519800000001,0.08111906599999999,0.044621167999999996,0.015099266,0.02201368,0.090515013,0.017161258999999998,0.0016160010000000002,0.053308162,1.215283235,2.626997034,-3.558646234,-2.89177607,-3.395999046,-4.811606353999999,-3.8358572239999997,-2.857992477,-4.418844909,0.038828496000000004,-3.85683012008667,-8.61833381652832,-6.299091339111328,-5.2783050537109375,-6.858105182647705 -1227,1227,Q88P,0.004069339,-0.002046575,-0.003931544,-1.051082846,-1.9268623630000001,0.04538372,0.033691344,-0.025552667,0.016553503,0.024020714,-0.028113864,-0.014349491,0.006486404,-0.7537054320000001,-1.348460259,-1.832166218,-2.021558507,2.070845646,1.55745784,-7.481086397,-7.668603554,-8.271829117000001,-6.771355301,-6.536837883,-8.156806129,-5.659667868,-0.88914366,-7.447295665740967,-10.577678680419922,-9.234394073486328,-9.068132400512695,-8.99637508392334 -1228,1228,Q88S,0.04584819,0.017622921,0.001565274,0.052350891,0.023680338999999998,-0.021339893999999998,0.061349062,0.030347317000000002,-0.001454297,0.0217976,0.013448241000000001,-0.004035483,0.007166031,0.059910211,0.04479157,0.037539151,0.009821527,1.0373781690000001,2.727818375,-1.831365651,-1.016592896,-1.6152179340000001,-1.9066915359999999,-2.351303444,-2.267022446,-4.137699422,1.343793049,-3.934100389480591,-8.112394332885742,-6.035988807678223,-4.2601847648620605,-6.715485572814941 -1229,1229,Q88R,-0.01289243,0.005446904,0.007890046999999999,0.03952838,0.016367382,0.003979693,0.024294977000000002,-0.050079835999999996,0.039696112,0.042148257,-0.031254449,0.047994660999999994,-0.032214567,0.068027447,0.011029313,0.050896934000000005,-0.01816217,1.199379632,2.858891578,-2.4828596419999998,-2.144382294,-2.314331551,-3.081089745,-2.605703911,-2.26879071,-4.12925958,0.685969675,-6.077719211578369,-7.7756500244140625,-7.345013618469238,-5.3857879638671875,-7.905477046966553 -1230,1230,Q88T,0.054437564,0.003298217,-0.005184350999999999,0.059950844,0.023069693999999998,-0.005686804,0.06190093,0.046974197,0.068469876,0.021302752999999997,-0.01470632,-0.014790447,0.004421745,0.070074622,0.049827065,0.023458215,0.022681172000000003,1.188531919,2.805887005,-3.4584377180000003,-3.115571442,-3.218177414,-3.536492599,-3.5212444310000004,-3.900702705,-4.3539349430000005,0.061247845,-5.945951461791992,-7.847689628601074,-7.119790554046631,-4.929972171783447,-7.061326026916504 -1231,1231,Q88W,-0.41284074299999995,0.0236892,0.031385505,0.09347412,0.052154614,0.0031223809999999996,0.044635009,-0.870316495,0.041508533,0.035905463,0.011472936000000001,0.030721397,0.032049612000000005,0.073282867,0.11366537300000001,0.050221334000000006,0.054087893,1.0882496640000001,2.8629471360000003,-8.837188876,-8.985157631,-8.643806488,-9.485841499,-8.663544563,-8.4075942,-7.052918603999999,-3.6153106839999998,-9.997197151184082,-12.42458438873291,-11.922208786010742,-9.508781433105469,-11.421570777893066 -1232,1232,Q88V,-0.002694602,-0.011098924,-0.018490376,0.039814456,-0.02038913,0.048306112000000005,0.007917262,-0.013306466000000001,0.127186679,0.043602325,-0.065800172,0.009339336,-0.046320087999999995,0.046639625,0.032989286,0.021582492,-0.062360751,1.178292594,2.721646774,-6.605669193,-7.32097242,-7.009054916,-6.48372123,-5.790046782999999,-6.424550612999999,-5.400797804,-1.205014349,-6.629580497741699,-9.259020805358887,-8.310556411743164,-6.400259971618652,-9.257847785949707 -1233,1233,Q88Y,0.062750868,0.036273293,0.059185774000000003,0.096223861,0.087859613,-0.040043254,0.055352346,0.070149389,0.000498419,-0.00957765,0.082124235,0.050635757,0.06773579099999999,0.034095971,0.15835175,0.045104045,0.13061518,1.103531468,2.759759629,-10.04468634,-8.867099701,-12.81490498,-10.72910564,-9.906172935,-7.90614843,-6.1642516579999995,-1.175744443,-7.629633903503418,-9.961315155029297,-10.034479141235352,-7.830406665802002,-10.355476379394531 -1234,1234,L89A,-0.0331373,0.026295917000000002,0.005897541,0.023746114,-1.51750046,0.029461063,-0.050264891,-0.016009708,0.058154965,0.012168565,0.040423269,-0.017321406,0.029116487000000003,0.036463649,0.011028578999999998,-1.395263142,-1.639737777,0.524565597,1.316404986,-6.850393228,-8.54612838,-5.599433121000001,-6.266668236,-4.268734589,-9.571001816,-5.757854804,-3.8387185280000002,-9.244466781616211,-14.692625999450684,-8.209151268005371,-11.446857452392578,-11.261043548583984 -1235,1235,L89C,-0.032035051,-0.047588781,0.000156431,-0.7387073829999999,-2.106335815,0.06663966,0.030760566,-0.094830667,-0.01316245,-0.010253018000000001,-0.084924543,-0.047435914,0.047748776,-0.357219189,-1.120195576,-1.846342595,-2.366329035,1.448092214,1.36903937,-9.333760998999999,-9.996754623,-8.107065094,-10.29357748,-7.340972725,-10.93043507,-8.574270392999999,-7.205445922000001,-12.01159381866455,-16.62268829345703,-11.743135452270508,-13.167741775512695,-14.787017822265625 -1236,1236,L89E,-0.14424067699999998,-0.005066387,-0.033061639,-0.11934807900000001,-2.122418487,0.067513892,-0.13035629699999998,-0.15812505699999999,0.016589631,-0.035970461,0.025837687999999998,-0.05643070099999999,-0.009692576,-0.037483386,-0.20121277199999998,-1.590093049,-2.654743924,0.606928577,1.312592777,-8.444922304,-9.161046158,-7.516256905,-9.309865532,-5.278616608,-10.95882632,-7.087193859,-4.707221621,-9.536839485168457,-15.324250221252441,-8.736329078674316,-13.45826530456543,-13.080450057983398 -1237,1237,L89D,-0.028070645,-0.011812418,-0.03718106,-0.567271936,-2.198119647,0.02975867,0.036569785,-0.092711075,-0.104575553,-0.023877187,0.000252352,-0.11035851199999999,0.035996393,-0.240018643,-0.894525228,-1.7906938069999998,-2.605545486,1.337945635,1.3612488880000002,-10.59852311,-11.13122562,-10.50541126,-11.12417969,-7.219189926,-13.01260904,-8.703510343,-6.994136912,-11.33845329284668,-15.764790534973145,-10.993200302124023,-13.406582832336426,-14.634995460510254 -1238,1238,L89G,-0.08410186800000001,-0.066134403,-0.017140445,-0.09238281300000001,-1.746458061,0.08169702400000001,-0.058392574,-0.10981116099999999,-0.064874377,-0.069999869,-0.062268936,-0.037232239,0.00295135,-0.023834576,-0.160931049,-1.6491433580000001,-1.843772763,0.8097827609999999,1.320241194,-8.905263551,-11.165894300000001,-6.790520821,-7.243362785,-6.352322327,-12.97421752,-6.909456621,-3.674713745,-11.408304214477539,-16.910524368286133,-11.707467079162598,-13.700881004333496,-14.299087524414062 -1239,1239,L89F,-0.071190157,-0.018021565,-0.054275304,-0.013491771999999999,-1.065589855,0.092708,-0.038948621,-0.10343169199999999,0.063829767,0.014628826000000001,-0.050671955,-0.050521842000000004,-0.058028765,0.012093332,-0.039076876,-0.69421588,-1.436963829,0.9774342229999999,1.48118201,-5.65416026,-4.495923042,-5.155984276,-7.491745323,-4.225370766,-6.901777892999999,-5.755822633999999,-3.207502007,-7.855340957641602,-10.448370933532715,-9.344610214233398,-8.983787536621094,-8.11259651184082 -1240,1240,L89I,-0.057288926,0.017897855,-0.000609927,0.019027822,-0.292830677,0.07447266,-0.052333629000000007,-0.062244222,0.0029923420000000003,0.043046144,-0.007250434,0.003479199,-0.004699053,0.045128678,-0.007073034000000001,-0.222177393,-0.36348396,1.129624275,1.903709181,-4.963014446,-3.959351097,-5.042844704,-6.540368103,-4.2997507630000005,-4.972757561,-6.687052916,-4.071985403,-5.901427268981934,-9.448607444763184,-6.453351020812988,-8.30443000793457,-8.315346717834473 -1241,1241,L89H,-0.066808811,0.037923032999999995,-0.002138622,-0.09919880199999999,-1.515653905,0.05619785,-0.032363972000000005,-0.10125365,-0.027921802000000003,0.008170796,0.06767526900000001,-0.028204555,0.023927312000000003,-0.042124708,-0.156272896,-1.326619888,-1.7046879209999999,0.62105932,1.325201835,-11.13889943,-11.87304268,-9.646602234,-13.14196828,-7.74784182,-13.28504211,-8.79962263,-7.838990008,-11.302162170410156,-14.89797592163086,-10.988753318786621,-12.43311595916748,-13.311917304992676 -1242,1242,L89K,-0.09268154,-0.042553043,-0.057566618,-0.9429244290000001,-1.9043932769999998,0.013784418,-0.06931723,-0.116045849,-0.0011868480000000001,-0.038075299,-0.047030786,-0.089104388,-0.026028847,-0.6782218320000001,-1.207627026,-2.045966312,-1.762820241,1.901376091,1.429161537,-7.882206352000001,-8.039312858999999,-6.838080307,-9.410864403,-4.972162872,-10.15061132,-6.648005591,-4.702790255,-12.15469741821289,-15.773626327514648,-11.366850852966309,-12.920477867126465,-13.315768241882324 -1243,1243,L89M,-0.000443625,0.045658412,0.022507745,0.026469617999999997,-0.068121536,-0.009742648000000001,-0.004588857,0.003701607,-0.01472993,0.06358678,0.027730043,0.024989584,0.020025906,0.054557014,-0.0016177779999999998,-0.036660103,-0.09958296800000001,1.186638969,2.423267269,-4.3301271130000005,-4.464801758,-4.513537842,-4.063312607,-3.514838379,-5.094144981,-4.764745769,-3.0499417689999997,-7.617973327636719,-8.985797882080078,-7.56569766998291,-8.472963333129883,-5.21252965927124 -1244,1244,L89N,-0.107009849,-0.054181648,-0.035920652000000004,-0.88043269,-1.80739076,0.045476998,-0.097235688,-0.11678401,-0.044719852000000004,-0.052161927999999996,-0.056201368,-0.04384728,-0.027994023,-0.486449687,-1.274415692,-1.8237642109999999,-1.7910173090000001,1.736100391,1.44378924,-10.90591121,-11.57756381,-9.295157425,-12.74595065,-8.201983734,-12.70890043,-9.998314173999999,-10.17081188,-11.159669876098633,-15.553274154663086,-11.268096923828125,-12.626452445983887,-13.382261276245117 -1245,1245,L89Q,-0.107186166,0.005015638,-0.052263443,-0.194378665,-1.814728086,0.016471031,-0.097317982,-0.11705435,-0.07618405,0.012991655,-0.00296038,-0.080622997,-0.023903887999999998,-0.057496415,-0.331260915,-1.518780292,-2.11067588,0.792977121,1.325654072,-9.383496912,-10.36147267,-8.377760925,-10.01275784,-6.680069939,-11.48542318,-7.881913441,-6.789696322,-9.923054695129395,-14.34768009185791,-10.412932395935059,-11.52065658569336,-11.573829650878906 -1246,1246,L89P,-0.09897177800000001,0.013461446,-0.01431799,-0.018416175,-1.452205367,0.081698752,-0.0587332,-0.139210355,-0.019419862,0.044820926,-0.017898034,0.024876274,-0.053512254,0.029419507999999997,-0.066251857,-1.18920866,-1.7152020730000002,0.600028982,1.3323421020000001,-4.349791417,-5.824621719,-3.7667021330000003,-4.10814518,-3.233888092,-4.81559996,-4.568451422,-2.410204968,-7.749500274658203,-12.389097213745117,-7.4306960105896,-10.239855766296387,-10.487421989440918 -1247,1247,L89S,-0.062074940999999995,0.012466753999999998,0.014875631,-0.039904976,-1.6795782819999998,0.036591066,-0.053425239000000006,-0.070724643,0.008494536,0.0171231,0.0078104080000000005,-0.003398579,0.033149841,0.017010312,-0.096820263,-1.565549464,-1.7936071,0.444772139,1.305615736,-7.523215785,-8.811308662,-5.523319252,-8.365351532,-5.4061026,-9.50999688,-6.389438281,-5.6908856729999995,-9.655159950256348,-15.003660202026367,-9.727027893066406,-12.019243240356445,-12.044902801513672 -1248,1248,L89R,-0.096017579,-0.018799198,-0.041750739,-1.3824425130000002,-2.009935743,0.09354610599999999,-0.056395342,-0.135639816,-0.024210455,0.001923363,-0.039521759,-0.043965622,-0.039535855,-1.090106123,-1.674778902,-1.672840867,-2.3470306180000002,3.092633872,2.351608227,-8.243879688,-8.656393852,-7.563850655,-8.754122261000001,-5.239022522,-11.00600915,-6.83988968,-4.232003412,-11.68678092956543,-14.117051124572754,-10.540736198425293,-12.628852844238281,-13.233270645141602 -1249,1249,L89T,-0.075303194,0.05099723900000001,-0.022623017000000002,-0.063514654,-1.712095064,0.037857075,-0.047637797,-0.10296859,0.017302295,0.065131414,0.036863063,-0.007854076,-0.037391957,0.020170445,-0.14719975300000002,-1.5442840740000001,-1.879906053,0.63772385,1.31531363,-7.4923834639999995,-8.266606987000001,-6.207190674,-7.900169579,-5.3434867939999995,-9.744463287,-7.020355919,-5.658127192,-8.214987754821777,-13.953590393066406,-8.562821388244629,-11.90678596496582,-10.462164878845215 -1250,1250,L89W,-0.011960913,0.016185593,0.050832994000000006,0.010374732,-1.733268579,0.07607939799999999,0.011712726000000001,-0.035634552,-0.024200127999999998,-0.009695460999999999,0.042066646,0.035453659,0.066212329,0.032927923,-0.012178458999999999,-1.453506344,-2.0130308130000003,0.669867962,1.3218184290000001,-8.652681238,-8.597268486,-9.088394775,-9.872710547999999,-5.025510574,-10.679521800000002,-6.2354838720000005,-3.727466158,-10.516215324401855,-12.817394256591797,-9.015636444091797,-12.460972785949707,-11.533645629882812 -1251,1251,L89V,-0.06768515900000001,-0.013697971000000001,-0.008251293,0.017593182,-1.52692744,0.051349592,-0.043935337000000005,-0.09143498,-0.075787687,0.004725165999999999,-0.032121107,0.010179981999999999,-0.026682567999999997,0.092129855,-0.056943492000000005,-1.3797746880000001,-1.674080191,0.458850662,1.313222772,-6.540043878,-6.485164795,-6.424135033,-7.324992073,-5.267949127,-7.197978363,-6.179949211,-4.783772744,-7.154885768890381,-13.061775207519531,-6.777377605438232,-9.756881713867188,-9.578463554382324 -1252,1252,L89Y,-0.075254154,0.0036586120000000003,-0.005657211,0.016827778,-1.435450717,0.113488515,-0.054164685,-0.096343623,-0.019203338,0.048914347999999996,-0.041597124,-0.016534552,0.00522013,0.048502109,-0.014846553,-1.425360386,-1.4455410469999999,0.534130177,1.3150967759999999,-9.192504749,-8.570032767999999,-8.857753357,-11.22088213,-6.385316536,-10.92853895,-6.781709923999999,-3.6356642999999997,-10.047246932983398,-12.776629447937012,-9.925311088562012,-11.292028427124023,-11.408257484436035 -1253,1253,G90A,-0.013649133,0.031624062,-0.042089287,0.013255168999999999,-0.011699145,0.067484269,0.027236271,-0.054534537,-0.052504123,0.05743088,0.005817243000000001,-0.010191369,-0.073987204,0.065193979,-0.038683642000000004,-0.008293503,-0.015104786,1.169637137,2.558734278,0.34778014700000004,0.502114807,-0.11991011,0.540211647,0.475235489,0.341248901,-0.8677787379999999,1.050190804,-3.4948551654815674,-7.002915382385254,-3.9046082496643066,-3.9353342056274414,-4.904322147369385 -1254,1254,G90C,0.073141673,0.006536330999999999,0.01349705,0.002004083,-0.975286612,0.107913466,0.056582713,0.089700633,-0.100014197,-0.036596392,0.049669054000000004,-0.063248099,0.09024219800000001,-0.048390006,0.05239817099999999,-0.87078115,-1.079792074,1.0145429259999998,1.436812988,-4.375274692,-3.990473106,-3.9855835039999996,-4.978669463999999,-4.195190437,-4.726456947,-6.109690809,-3.895430461,-7.128994941711426,-12.10574722290039,-8.617256164550781,-8.444463729858398,-12.492152214050293 -1255,1255,G90E,0.02561343,-0.015886723999999998,-0.018965453,0.013572236000000001,0.041201227,0.012981401000000002,0.038608126,0.012618733,-0.052711037,0.005447952,-0.0372214,0.016528821000000003,-0.05445972599999999,0.033237976,-0.0060935040000000005,0.051468814,0.03093364,1.110969013,2.691206778,1.5781998169999998,1.546856384,1.606468582,0.981505455,2.3012014080000003,1.454967255,-0.39748940299999996,1.229441899,-1.0902061462402344,-4.283930778503418,-1.587374210357666,-2.281291961669922,-3.5455238819122314 -1256,1256,G90D,-0.060325971,-0.06504227900000001,-0.057216786,-0.032171239,-0.005478861999999999,0.011807307,-0.023678331,-0.09697361,-0.145721249,-0.014955032,-0.115129526,-0.039052177,-0.075381395,0.049052557000000004,-0.113395035,-0.002555197,-0.008402527,1.374463217,2.813746024,2.33596237,2.31446077,1.7322798609999999,1.728860184,3.5145794830000003,2.389631554,1.167093816,2.6197071640000003,0.25079721212387085,-2.3256516456604004,0.3220372200012207,0.025988101959228516,-3.700727939605713 -1257,1257,G90F,0.042628124,-0.024018391,-0.078979982,0.037264197,-0.131499981,0.010466486,0.065979325,0.019276922,-0.12481385,0.040068135,-0.08810491599999999,-0.04900766,-0.108952304,0.0683284,0.006199994,-0.070744268,-0.19225569399999998,1.260296383,2.376456284,-4.29258084,-3.552814285,-3.769783119,-5.788547501,-3.918591888,-4.433167404,-5.321456885,-3.105097895,-5.9589080810546875,-11.316076278686523,-6.958765029907227,-7.169045925140381,-8.688335418701172 -1258,1258,G90I,0.002888562,-0.064936436,-0.026845417000000003,0.013477233,-0.13522483300000002,0.021733745,0.039848469,-0.034071346,0.013850265,-0.037380698,-0.09249217300000001,-0.002474619,-0.051216214,0.011964383,0.014990082,-0.097576952,-0.172872713,1.307517609,2.2875449690000003,-4.439312163,-3.4452963710000004,-4.549177803,-5.130625496,-4.27754081,-4.793920334,-5.442943898999999,-3.5939823719999997,-5.217101097106934,-12.102888107299805,-8.345539093017578,-7.468470096588135,-7.272531509399414 -1259,1259,G90H,-0.035120017999999996,-0.00225988,-0.046302202,-0.022072485,-0.0363664,0.015426306,0.001165859,-0.071405895,-0.054758920999999995,0.087495374,-0.09201513300000001,-0.001142491,-0.09146191199999999,0.08802538800000001,-0.132170357,0.022700627,-0.095433426,1.161577178,2.80785781,-2.214704089,-2.184244568,-2.184709663,-2.9933678130000003,-1.3430709230000002,-2.36812748,-3.7010980630000003,-0.526488823,-3.9333527088165283,-7.144413471221924,-4.0083088874816895,-4.950694561004639,-6.852467060089111 -1260,1260,G90K,-0.047787407999999996,-0.044188693,-0.07503638900000001,-0.026130331,-0.108828669,0.030080282000000003,-0.033801923,-0.061772892999999995,0.027623552000000003,0.003706253,-0.09208363800000001,-0.023993835,-0.126078942,0.029014982,-0.08127564400000001,-0.064238083,-0.153419254,1.3087248409999999,2.444385149,-1.029455095,-0.665827843,-1.022767685,-2.153696175,0.290692223,-1.595675995,-3.5614084160000004,-0.5242448670000001,-5.76458740234375,-9.424457550048828,-5.873837947845459,-6.009563446044922,-6.06785249710083 -1261,1261,G90M,-0.077176066,0.020540893,-0.061032885,-0.03129388,-0.039755865,0.057239852,-0.059311494000000006,-0.095040637,-0.054770488,0.075723731,-0.034641946,-0.050641593,-0.07142417599999999,0.029923518,-0.09251127699999999,-0.028009742,-0.051501988,1.153119917,2.483269178,-3.380902838,-3.0960743789999996,-3.224320137,-4.339163193,-3.0489571989999997,-3.195999283,-4.6907080830000005,-2.197064398,-5.643247604370117,-10.19145393371582,-6.796196937561035,-6.258132457733154,-5.887293815612793 -1262,1262,G90L,-0.022481755,-0.036988303,-0.045980277,-0.042022018,-0.128355617,-0.0026366209999999996,-0.019120553999999998,-0.025842955,-0.02504406,0.017058429,-0.091035034,-0.027581368,-0.06437918599999999,-0.008597776,-0.07544626,-0.08607041,-0.170640824,1.317843664,2.272856615,-3.6578066010000003,-3.357116364,-3.359164497,-4.359600189,-3.39148851,-3.821663445,-5.1270391239999995,-1.8401084069999998,-4.37424373626709,-10.088682174682617,-6.6489996910095215,-6.2288079261779785,-6.4503607749938965 -1263,1263,G90N,0.006343596999999999,0.030640358,-0.032043377000000005,-0.057378282,0.017350078999999997,0.031535966,0.06217728,-0.049490085999999996,-0.022617247000000004,0.083460573,-0.022179857,-0.019254799,-0.044831955,-0.07962124400000001,-0.035135319,0.024723835,0.009976322,1.246537915,2.6730107000000003,0.461524382,0.903820244,0.194623665,-0.936723015,2.509061478,-0.363160461,-1.174435143,1.098494901,-2.3459253311157227,-5.1043500900268555,-2.596405506134033,-2.356670379638672,-5.114934921264648 -1264,1264,G90Q,0.017906928,-0.012561158000000001,-0.024980777000000003,0.001080846,0.072975398,-0.027823412999999998,0.030618935,0.00519492,-0.006817212,0.0055737980000000005,-0.030696114,0.008434617,-0.058396171,0.015396911999999999,-0.01323522,0.03720463,0.10874616599999999,1.144309066,2.690097492,-0.225791658,-0.060725449,-0.541879868,-0.766580666,0.317155289,-0.076927597,-2.9089692510000003,0.38408995,-3.458754301071167,-6.719222545623779,-4.0269246101379395,-4.514150142669678,-4.906710624694824 -1265,1265,G90P,-0.013313483999999999,-0.012883043,-0.053745142,-0.027673671,-0.68542057,0.069054024,0.012811323000000001,-0.039438291,-0.018589675,0.048545831,-0.07431191599999999,-0.051992995,-0.055497288,0.016172166,-0.071519508,-0.482410657,-0.8884304829999999,1.037036757,1.574487789,-3.999522859,-3.957960838,-4.067958153,-4.165689438,-3.940905617,-3.86510025,-4.870941022,-2.9248922530000003,-6.225475311279297,-11.440516471862793,-8.921689987182617,-8.081825256347656,-10.134042739868164 -1266,1266,G90S,-0.024565003999999998,-0.007594556,-0.037740391,-0.036856002,-0.020904624,0.008073971,-0.01278993,-0.036340078,-0.025510036,0.011574067,-0.026763178999999998,-0.013209936,-0.062270846,0.010040401,-0.083752405,-0.028674188,-0.013135059,1.2058970359999999,2.468424679,1.199482962,1.618060768,1.671185806,0.663164131,1.086216354,0.95878775,-1.733391537,1.014104043,-2.226517677307129,-5.870768070220947,-3.244502544403076,-3.4135470390319824,-5.069291114807129 -1267,1267,G90R,-0.011144793,-0.029979371,-0.027049356,-0.028472152999999997,-0.145842567,0.066396362,0.013568598999999999,-0.035858185,-0.047361484,0.00678143,-0.066740172,0.017705916000000002,-0.071804628,0.016812739,-0.073757045,-0.093500585,-0.198184549,1.4161064140000001,2.383663826,-2.3517706990000002,-2.787357956,-2.659085403,-2.551516113,-2.200635124,-1.560258896,-3.955069528,-0.129797563,-6.580588340759277,-9.683161735534668,-6.66511869430542,-6.706838130950928,-7.58389139175415 -1268,1268,G90T,-0.01367986,-0.009774634,-0.05549761,-0.014621773999999999,-0.032386576,0.027424319,0.015698497,-0.043058217,-0.0800005,0.007263375999999999,-0.026812644,-0.058674599,-0.05232062,0.02438371,-0.053627258,-0.002251031,-0.06252212,1.19982473,2.625129314,0.332218887,1.087582489,0.6897421420000001,-0.22915313699999998,-0.063707809,0.176630753,-1.7138391990000001,0.9082618809999999,-2.8506059646606445,-6.063687324523926,-3.020155429840088,-3.9813790321350098,-5.360877990722656 -1269,1269,G90W,0.031069977000000002,-0.06479175599999999,-0.115450201,-0.076960094,-0.044056476,-0.024997495,0.061015905999999995,0.001124048,-0.07213301700000001,-0.058971317,-0.070612194,-0.11281117,-0.11808923199999999,-0.00405294,-0.149867248,-0.032777291,-0.05533566,1.155281826,2.460090148,-5.044825684,-4.739189026,-4.707842316,-6.01606926,-4.563046707,-5.19798111,-5.574649302,-3.987336781,-7.163839340209961,-12.588842391967773,-7.916778087615967,-7.769241809844971,-8.14798641204834 -1270,1270,G90V,-0.037485835,-0.00797489,-0.032687119,-0.022575779,-0.155368692,0.063601296,-0.033852512,-0.041119157999999996,-0.020487711999999998,0.03462074,-0.05057052,-0.051840005999999994,-0.013534231,-0.012513136000000001,-0.032638421,-0.093473901,-0.217263483,1.376014197,2.397550292,-4.381040456,-3.6923404539999995,-4.47302375,-4.822299583,-4.329286354,-4.588252136,-5.905766611000001,-3.691706707,-5.1484527587890625,-10.7485990524292,-6.959273338317871,-6.561799049377441,-6.660401821136475 -1271,1271,G90Y,0.045050518,-0.006018651999999999,-0.047921822,-0.026719792000000003,-0.065199464,-0.037243736,0.039923636,0.050177399000000004,-0.039058585,0.042216339000000005,-0.054253643,-0.061164007,-0.034679637,-0.029768751,-0.023670832000000003,-0.091118209,-0.039280718,1.364757095,2.331489033,-3.110277296,-2.272916641,-2.363801697,-4.371236641,-2.830959908,-3.7124715960000003,-3.802099989,-1.97873753,-5.722566604614258,-10.192241668701172,-6.333205699920654,-6.165579319000244,-8.446977615356445 -1272,1272,R91A,-0.00967035,0.05578526599999999,0.006254716,0.017544558999999998,-1.352936045,0.016006488,-0.019793734,0.000453035,-0.023253102,0.076339739,0.035230792999999996,0.027031401,-0.01452197,0.060408820999999994,-0.025319703,-1.07582265,-1.630049439,0.644716279,1.342459752,-5.840380174,-4.655249939,-7.064129157999999,-6.452024155,-5.65620504,-5.37429258,-4.3619854469999995,-1.4062586419999998,-9.282339096069336,-12.74780559539795,-7.410137176513672,-11.666574478149414,-11.55572509765625 -1273,1273,R91C,-0.028013412,0.029660241,-0.163516514,-1.296169983,-1.363640025,0.058398075,0.002028667,-0.05805549,0.074262809,0.051148858,0.008171623000000001,0.055925055,-0.38295808299999995,-1.0698164959999998,-1.52252347,-1.69776873,-1.02951132,2.7728579539999996,2.077546304,-10.27884372,-9.07363279,-11.05307439,-11.00135783,-9.738714118999999,-10.52743948,-7.7328675229999995,-5.4305773010000005,-10.955370903015137,-11.987733840942383,-10.301945686340332,-12.164690017700195,-11.733505249023438 -1274,1274,R91E,-0.023438773,0.064751486,0.059554225,-0.017830672,-1.8431241630000001,-0.006955819,0.004490597,-0.051368143,-0.039733244,0.076561144,0.052941827999999996,0.053459409000000006,0.06564904099999999,0.052639222,-0.088300565,-1.528472829,-2.157775497,0.664844662,1.317157412,-5.615023412,-4.520169151,-5.895663811,-6.016223198,-4.86084845,-6.782212447999999,-4.350516488999999,0.055298162000000005,-9.292147636413574,-12.648651123046875,-7.1389312744140625,-11.764376640319824,-12.338101387023926 -1275,1275,R91D,-0.09011313300000001,0.054419126,0.028988269,-0.135003069,-1.653138449,0.012118761,-0.069764831,-0.110461434,0.032807231,-0.010537709,0.11937596,0.018791045,0.039185492999999995,-0.021384847999999998,-0.248621289,-1.434527295,-1.871749602,0.753720389,1.328321211,-4.667224915,-3.033386932,-5.960324432,-5.854367927999999,-3.541084572,-4.946960709,-3.334611166,-0.21515210899999998,-10.049612045288086,-13.935691833496094,-7.646390914916992,-13.139304161071777,-13.254072189331055 -1276,1276,R91G,-0.036362733,0.02729582,-0.004293671,-0.843676104,-1.8398286419999998,-0.014140811999999999,-0.0077930840000000005,-0.064932381,0.01458025,0.024852125,0.029739513999999998,-0.021342929,0.012755586999999999,-0.5320690610000001,-1.155283146,-1.757597681,-1.9220596030000001,1.8009588380000001,1.478660284,-8.603991108999999,-7.6487215729999996,-9.472006805,-9.429393639,-7.880559578,-8.589273948999999,-6.567185891,-3.550973145,-10.165422439575195,-12.478029251098633,-9.01671314239502,-12.543724060058594,-12.531877517700195 -1277,1277,R91F,-0.033950647,0.066268207,-0.029661079,-0.154379854,-2.190379396,-0.049434724000000006,-0.042734833,-0.02516646,0.086840222,0.053007135999999996,0.079529278,-0.065033942,0.005711785,-0.105320679,-0.203439029,-1.9726460069999998,-2.408112784,1.003704556,1.30917829,-11.84216129,-9.664563507,-11.35103831,-12.773514500000001,-11.75563979,-13.66605032,-8.19478142,-5.921714764,-13.660652160644531,-16.212223052978516,-12.136555671691895,-14.046728134155273,-14.162345886230469 -1278,1278,R91I,-0.056227788,0.003949605,0.003976111,-1.342748218,-1.776368346,0.037391957,-0.063466133,-0.048989443,0.0013740129999999999,-0.015288745,0.023187955,-0.032830677999999995,0.040782900000000004,-1.058869316,-1.6266271190000001,-1.7116451330000002,-1.841091558,3.43709409,2.683243196,-10.01708651,-9.062224045,-11.20580643,-10.34726086,-9.367227837,-10.10291337,-7.553228699,-5.36454876,-12.90567398071289,-14.798662185668945,-10.658795356750488,-12.876604080200195,-12.811430931091309 -1279,1279,R91H,-0.002327235,0.050562125,0.008185056,-0.041614867,-0.08997326900000001,-0.000980151,-0.03265535,0.028000881000000002,0.017979765,0.013219635,0.087904614,-0.04529347400000001,0.061663586,-0.039542033,-0.043687699999999996,-0.123303385,-0.056643152999999995,1.326909262,2.244538031,-5.355508748,-5.162794487,-5.642671668999999,-5.948014999,-5.081060905,-4.943001678,-5.190025438999999,-2.6468990519999998,-9.127025604248047,-9.979768753051758,-7.923637390136719,-9.045639991760254,-8.884724617004395 -1280,1280,R91K,-0.016886984,0.030871008999999998,0.044181244,-0.008050241999999999,-0.12475316199999999,0.002753525,-0.026741721,-0.007032246999999999,0.011060307,0.042053352999999995,0.019688665,0.044154835999999996,0.044207650999999994,0.00312702,-0.019227503,-0.060279,-0.18922732399999997,1.543610422,3.106887046,-4.997492682,-3.966701485,-5.2420356980000005,-5.305514763,-4.398279778,-6.074931686,-4.077314994,-0.961435268,-7.854619979858398,-9.032007217407227,-5.17014741897583,-7.977344512939453,-7.5445637702941895 -1281,1281,R91M,0.016601234,0.004205370999999999,-0.001891278,0.048651268,-1.473200085,-0.001097249,0.02318271,0.010019756999999999,-0.048839022,-0.014966017,0.023376759,-0.053902752000000005,0.050120196,0.050901743,0.046400792999999996,-1.50294877,-1.443451399,0.660407842,1.3186029609999999,-8.425528963,-7.51768515,-8.804548561,-8.749572639,-8.160226219,-8.895612244,-5.903176602,-3.663119131,-11.995113372802734,-13.092826843261719,-8.896002769470215,-11.893957138061523,-12.394271850585938 -1282,1282,R91L,-0.040372273,0.034529846,-0.018983322,-0.356925079,-1.701135439,0.033695024,-0.000366401,-0.080378145,-0.025442076,0.008720858,0.060338834,-0.022526504,-0.01544014,-0.155890262,-0.5579598960000001,-1.6436348269999999,-1.75863605,1.1087180429999999,1.349132705,-8.544838103,-8.215568665,-7.8623594279999995,-9.440935248999999,-7.895217545,-9.310109627000001,-6.344775847,-4.051053959,-10.632275581359863,-12.791853904724121,-8.730578422546387,-11.512726783752441,-11.064868927001953 -1283,1283,R91N,0.024183516000000002,0.065282619,0.003236394,0.043835618,-0.512989782,-0.010320457,0.0042813320000000005,0.044085699000000006,-0.027981381,0.015579981000000001,0.114985257,0.0049869070000000005,0.00148588,0.054458365,0.03321287,-0.39134962700000003,-0.6346299360000001,0.959204707,1.594013465,-6.664937654,-5.698930054,-8.23853019,-6.923328285,-5.965567711,-6.498332031,-4.759600775,-3.439779182,-10.185860633850098,-11.82731819152832,-8.36711311340332,-10.808380126953125,-11.015499114990234 -1284,1284,R91Q,0.003279587,0.076524345,0.018904481,0.060764535999999994,-1.3668792369999998,0.04569659400000001,0.041986792,-0.035427619,0.039561558,0.081928661,0.071120028,0.046292977,-0.008484015,0.075508883,0.046020189,-1.177311635,-1.5564468390000001,0.662049847,1.3370498990000002,-4.460664192,-3.8052919160000003,-4.983805611,-4.035660782,-4.186394241,-5.2921684110000005,-3.813614832,-0.02630033,-7.782468318939209,-8.632617950439453,-3.749235153198242,-8.44770622253418,-8.09167766571045 -1285,1285,R91P,-0.019689701,-0.351512703,-1.684834607,-2.050477453,-2.571355016,-0.061552024000000004,-0.012371756999999999,-0.027007644,0.012672393999999998,-0.24321341300000002,-0.459811993,-1.5955793180000002,-1.774089896,-2.07113481,-2.029820096,-2.396087455,-2.7466225769999997,1.215644032,0.07561198200000001,-11.09000541,-9.916807327,-12.15708882,-11.97887112,-10.427356,-10.96990378,-9.409700667000001,-8.783288814,-10.516477584838867,-14.172527313232422,-10.56523323059082,-13.001816749572754,-13.40024471282959 -1286,1286,R91S,-0.05486617,0.034438365,-0.01879807,0.006838716,-1.3524947180000002,0.059137029,-0.044184738,-0.065547601,-0.02003438,0.003832443,0.065044287,-0.012678143000000001,-0.024917996,0.024023182,-0.01034575,-1.372534984,-1.332454451,0.46696642899999996,1.312525447,-5.9304858629999995,-5.694097954,-6.636045403,-7.008242111,-5.538773262,-4.775270583999999,-4.933649994,-1.671240351,-9.138389587402344,-11.361411094665527,-6.937944412231445,-10.625040054321289,-10.669279098510742 -1287,1287,R91T,0.006034024,0.016851294,-0.0012853,0.011774613,-0.598956526,0.000731268,-0.010634444,0.022702492,-0.00866148,0.040466962999999995,-0.006764376,0.00969554,-0.012266138999999999,0.029292285,-0.00574306,-0.47913618799999996,-0.7187768640000001,0.388446809,1.377261345,-5.215698592,-4.495002243,-5.708961456,-5.846373665,-5.148950684,-4.87920491,-4.407822191,-0.8665416359999999,-9.430313110351562,-12.182984352111816,-6.99935245513916,-10.344265937805176,-10.935230255126953 -1288,1288,R91W,-0.050481585999999995,0.069254133,-0.003473855,-1.250980008,-2.215240255,0.008275399000000001,-0.018429021,-0.08253415,-0.041056143999999996,0.146873801,-0.008365536,0.022894148,-0.029841857000000003,-0.837313119,-1.664646897,-1.7277319530000002,-2.702748557,2.332359363,1.762587074,-10.62294972,-9.998049957000001,-11.03666017,-11.18492781,-10.45752449,-10.43758615,-8.710030576,-7.207296212999999,-12.184443473815918,-12.855311393737793,-12.26648235321045,-13.066166877746582,-12.014813423156738 -1289,1289,R91V,-0.018346995,0.027888465,-0.012152521999999999,-0.5130226689999999,-1.920734529,0.07378203,0.009377406999999999,-0.046071395999999994,-0.078731592,-0.019696836000000002,0.075473766,-0.053851834,0.029546791,-0.294613795,-0.731431543,-1.866273866,-1.975195192,1.4228090359999999,1.362824807,-9.823598924,-8.5694944,-11.25666138,-10.21012211,-9.235946739,-9.845769997,-7.585390583,-5.256167918,-11.716882705688477,-15.280616760253906,-10.068750381469727,-13.155693054199219,-13.11498737335205 -1290,1290,R91Y,-0.070865199,0.10684439800000001,-0.0077400659999999994,-0.019365663999999998,-2.267574631,0.038788245,0.016376676,-0.15810707400000001,0.065765512,0.07733138,0.136357416,0.025427923999999998,-0.040908056,0.000534427,-0.039265754,-1.7861349690000001,-2.749014292,0.737933925,1.308669763,-11.51182513,-10.555996400000002,-12.44442852,-11.79199636,-11.22773044,-11.53897393,-7.9974354729999995,-5.981887541,-12.076157569885254,-13.721789360046387,-11.181827545166016,-13.481181144714355,-12.592565536499023 -1291,1291,R92A,0.026271627999999998,0.019577266,0.009473914,-0.053823062000000005,-0.617133217,-0.019135413,0.002922575,0.04962068099999999,-0.054635715999999994,-0.025488952999999998,0.064643485,0.005147109,0.013800718,-0.064472997,-0.043173126,-0.434919922,-0.7993465120000001,1.34391434,1.7868211880000002,-3.984273944,-3.516363075,-4.365804031000001,-4.978966225,-4.130205353,-2.9300310360000004,-4.83048032,-2.192383569,-9.68727970123291,-12.15003776550293,-9.097707748413086,-10.074159622192383,-11.767715454101562 -1292,1292,R92C,0.018251484,0.06336801,0.07450053400000001,-0.067920639,-1.457742572,-0.024893836000000003,-0.0036579959999999997,0.040160963,-0.049334907000000004,0.045328405,0.081407614,0.08109888700000001,0.06790218099999999,0.028657282000000003,-0.16449855900000002,-1.327608473,-1.5878766709999999,0.640356936,1.3264569179999999,-7.368115352,-6.548204544,-8.479263367,-7.795987244,-8.108190628,-5.908930977000001,-7.561589766,-4.956647049,-10.556564331054688,-11.53671646118164,-9.080883026123047,-11.299578666687012,-12.221121788024902 -1293,1293,R92E,-0.039345628,0.00232509,-0.008034666999999999,-0.016457714,-0.591414856,-0.0056637630000000005,-0.034427252,-0.044264002999999996,-0.088363019,0.010561055,-0.005910876,0.047788597,-0.06385793,-0.016425508999999998,-0.016489919,-0.308839911,-0.8739898009999999,1.624941907,2.169335106,-5.250857617,-5.028100693,-6.579368011000001,-5.674376732000001,-6.183623299,-2.7888193510000003,-4.740956027,-1.552171489,-11.458327293395996,-13.450272560119629,-9.628340721130371,-11.764101028442383,-12.890413284301758 -1294,1294,R92D,0.00152879,0.051200138,0.05550978,-0.061650037000000005,-1.554089535,-0.039839619,-0.012437256,0.015494836000000001,-0.119771065,0.064008988,0.038391287,0.0743175,0.03670206,0.046782711,-0.170082785,-1.569075835,-1.5391032340000002,0.574707504,1.311379929,-7.269385872999999,-6.737715439,-8.236469223,-7.871647652,-7.530812263,-5.97028479,-7.172757021000001,-4.434305125,-10.989097595214844,-14.106893539428711,-11.327537536621094,-12.875614166259766,-14.359612464904785 -1295,1295,R92G,0.01619548,0.019031882,0.012819025,-0.08704626300000001,-1.714960669,-0.060118520999999994,-0.002349509,0.034740468,-0.049294240999999996,0.020668392,0.017395372,-0.0041604979999999995,0.029798547,-0.012189748,-0.161902777,-1.68155848,-1.7483628569999998,0.596479557,1.307477768,-6.51556158,-5.90240667,-7.291848145,-7.260743431,-7.062835982999999,-5.059973671,-6.637216627000001,-4.118027833,-11.746582984924316,-13.062931060791016,-11.579526901245117,-12.846105575561523,-13.234379768371582 -1296,1296,R92F,-0.054596324,0.030921571000000002,-0.007493579,-0.052940994000000005,-0.302908098,-0.009861701,-0.09796576300000001,-0.011226885,-0.10061373300000001,0.005772436999999999,0.056070704000000006,-0.001364175,-0.013622981999999999,-0.0023310270000000003,-0.10355096,-0.195704018,-0.410112177,1.081654945,1.8600571,-5.891791014,-5.904228653,-7.2565380710000005,-6.277097457999999,-5.777193405,-4.243897484,-5.54054542,-4.0964100519999995,-9.685239791870117,-11.573698043823242,-8.033407211303711,-8.264507293701172,-10.805863380432129 -1297,1297,R92I,0.000744773,-0.009399505,0.063025905,-0.015121806000000002,-0.036945939,-0.0951893,-0.092134099,0.093623645,-0.058526966,-0.022507925,0.003708915,0.065337087,0.060714723,0.00679796,-0.037041571,0.020260078,-0.094151955,1.069686565,2.61208164,-4.672584721000001,-4.742434875,-6.666088318,-4.353712654,-4.8020123439999995,-2.798675415,-4.944547964,-2.1760084930000003,-9.215533256530762,-12.307596206665039,-6.973084926605225,-7.393284797668457,-9.09086799621582 -1298,1298,R92H,0.031071084,0.11987474099999999,0.024042967999999998,-0.028964305,-0.103741082,-0.036856112999999996,0.03264855,0.029493618,-0.10029551800000001,0.033087198,0.206662283,0.009694169,0.038391766,0.002241957,-0.060170567,-0.13532386300000002,-0.072158301,1.5268203619999998,2.38409496,-3.53959453,-3.4944493939999997,-3.941037521,-4.222607826,-2.910080002,-3.129797905,-4.970139946000001,-2.9812249210000004,-8.486791610717773,-8.082521438598633,-8.08784008026123,-8.452223777770996,-8.351774215698242 -1299,1299,R92K,0.058331875,0.09893235199999999,0.049226232,0.047867058,0.025212107,0.004889773,0.055693550999999994,0.060970197999999996,-0.077911211,0.089501311,0.10836339199999999,0.044465221,0.053987242000000005,0.049606012000000005,0.046128103,0.08505002199999999,-0.034625808,1.085829812,2.977637993,-3.1890761110000003,-2.8451103360000003,-3.758185371,-3.721832352,-3.80005986,-1.820192635,-4.063320022,-0.712624122,-7.967909812927246,-7.5123491287231445,-4.640140533447266,-5.626682281494141,-6.857453346252441 -1300,1300,R92M,-0.016017454,-0.00151728,0.008420658000000001,-0.051829907,-0.042024153,-0.09005054400000001,-0.068806412,0.036771505,-0.012782756000000001,-0.027071481,0.024036921,0.045946767,-0.029105452,-0.005988023,-0.09767179,0.023790826,-0.10783913199999999,1.229112177,2.776510943,-5.058031693,-4.600204323,-6.992193695,-5.670878448,-5.464441902000001,-2.5624400940000003,-5.573532002,-2.0785086759999998,-8.086360931396484,-12.13875675201416,-8.13860034942627,-7.192554950714111,-9.332328796386719 -1301,1301,R92L,0.002988863,0.033411067,0.005582826999999999,-0.025985269,-0.044805637,-0.06161556,0.000854523,0.005123202,-0.045036346,0.01217925,0.054642882999999996,0.018211585,-0.007045931,-0.006188931,-0.045781607,-0.026007317999999998,-0.063603956,1.671448915,3.643209181,-4.618163457,-3.81513678,-6.296243782,-5.323698936,-4.631976997,-3.023760788,-4.7954005969999995,-1.722096549,-7.389955043792725,-9.852812767028809,-6.760740280151367,-5.26390266418457,-8.271466255187988 -1302,1302,R92N,0.023811185,0.057440782,0.009103993000000001,-0.000378256,-0.266378004,-0.003606916,0.005327039,0.042295331,-0.082965768,0.035128873,0.07975269,0.046974003,-0.028766017,0.005462574,-0.0062190859999999995,-0.177220612,-0.355535396,1.355919774,2.133455404,-5.694545617999999,-5.071522301,-6.983017464,-6.647480461000001,-5.516918251,-4.253789612,-5.982278946,-3.156443377,-10.952938079833984,-10.949989318847656,-9.388163566589355,-10.786223411560059,-11.317081451416016 -1303,1303,R92Q,0.05295647,0.035158665,0.028091881000000003,0.023782552999999998,-0.112583396,0.001161048,0.027516227,0.07839671299999999,0.001346553,0.011537368000000001,0.058779962000000005,0.023719814,0.032463947,0.008355141,0.039209965,-0.04915913400000001,-0.17600765699999998,1.3068407,2.527913776,-4.054557207,-3.416456375,-5.473992546,-4.224748161,-4.097145248,-3.0604437030000002,-5.111399461,-1.605470049,-9.230096817016602,-8.736628532409668,-7.402059555053711,-8.090728759765625,-9.617368698120117 -1304,1304,R92P,0.027726756,0.071519341,0.047272540999999994,0.017053733999999997,-0.997423642,0.00615767,0.004836391,0.050617120999999994,-0.084588705,0.022100218999999997,0.12093846300000001,0.039957345,0.054587736,0.0062435,0.027863968,-0.738292352,-1.256554932,0.7690083529999999,1.40133507,-3.6754997439999997,-3.283137505,-3.3930104219999997,-5.374421196,-4.587670692,-1.7392589040000002,-4.5318925089999995,-0.947335783,-7.948603630065918,-11.07185173034668,-9.551434516906738,-9.09280014038086,-10.558113098144531 -1305,1305,R92S,0.033265449,0.050078673,0.01158973,-0.022563182,-0.379494693,-0.006331725,0.019463649,0.047067249000000005,0.014575487,-0.013259276,0.113416622,-0.01731329,0.040492749,-0.039427722000000005,-0.005698641999999999,-0.28136355399999996,-0.477625831,1.326018949,1.9126040069999999,-3.744684401,-2.771876694,-4.623070885,-5.446083412,-3.1413031080000002,-2.741087906,-4.426371704,-1.552332475,-9.607088088989258,-10.835615158081055,-8.658923149108887,-10.058443069458008,-10.892191886901855 -1306,1306,R92T,0.008648039,0.040669226,0.022357452000000003,-0.030511688,-0.029915213,-0.090280131,-0.050383826,0.067679903,-0.019934973,0.033441198,0.047897253,0.067260615,-0.022545711,-0.016070838,-0.044952537,0.016771794,-0.076602219,1.172144321,2.639365773,-3.4888100860000004,-3.048537949,-4.304962959,-4.590287238999999,-3.1212321089999997,-2.379030174,-3.586286846,-1.08204136,-9.646453857421875,-11.411709785461426,-7.56190299987793,-9.052021980285645,-10.30402660369873 -1307,1307,R92W,0.022277446,-0.023962126,0.035816508,0.006838099,-0.434074301,0.01997028,0.034214989,0.010339902,-0.071046132,-0.049432857000000004,0.001508605,0.053167385,0.01846563,0.009580414,0.004095784,-0.278668812,-0.58947979,1.107573596,1.774359031,-6.833058815,-6.583540245,-7.633850197,-7.16811515,-7.157276955,-5.6225115279999995,-7.058713057,-5.149445707,-10.449270248413086,-12.575645446777344,-10.336520195007324,-8.54489803314209,-10.929641723632812 -1308,1308,R92V,0.021690624,0.030863001,0.03761103,-0.038880752000000005,-0.051775185,-0.049594440999999996,0.002897334,0.040483913999999996,-0.026783092,-0.017132959,0.07885896099999999,0.022226976000000002,0.052995084000000005,-0.00845658,-0.069304923,0.000861334,-0.10441170400000001,1.231685683,2.676286906,-3.573799747,-3.674527771,-5.340761734,-2.70908857,-4.0202420960000005,-2.124378563,-4.032084053999999,-0.911518376,-8.126411437988281,-12.66861343383789,-7.030991077423096,-7.428792476654053,-8.787630081176758 -1309,1309,R92Y,0.12528215,0.139720665,0.133774451,0.020753554,-0.049946375,-0.034055132,0.048149711,0.20241458899999998,0.033979814,0.05400671,0.22543462,0.113645533,0.153903369,0.010916165,0.030590943,-0.096883039,-0.00300971,1.122556846,2.1778621719999998,-6.487003258,-6.143374832,-8.037272881,-6.655966857999999,-7.161269676,-4.437132042,-7.65887629,-4.79215794,-10.092093467712402,-11.432883262634277,-9.262029647827148,-9.072616577148438,-11.1019868850708 -1310,1310,I93A,0.061037032000000005,0.10923835800000001,0.095648303,-1.266763837,-1.960784664,0.080064377,0.09714996099999999,0.024924103,-0.08628753300000001,0.130303996,0.08817272,0.048357200999999995,0.142939405,-1.168394752,-1.3651329209999998,-1.7291740230000001,-2.192395304,3.0066701989999998,2.242778209,-6.438436014,-6.421102303,-6.4257481,-5.975035736000001,-8.096242683,-5.274051247,-5.419369782,-3.7856560760000004,-12.302472114562988,-11.76860237121582,-10.483196258544922,-11.892850875854492,-11.356101989746094 -1311,1311,I93C,-0.08862582,0.026995981000000002,0.040232869,-0.610789686,-2.445633448,0.29642875399999996,-0.045889663,-0.131361977,-0.041324726,0.08982659,-0.035834628,0.131420864,-0.050955125999999996,-0.301616032,-0.919963339,-2.17091332,-2.720353575,1.255544213,1.307548263,-9.52363549,-9.459982101,-9.218260772999999,-11.10804194,-9.790346176,-8.041546463,-8.0455945,-6.027269829,-13.467672348022461,-14.971476554870605,-12.121867179870605,-13.9717378616333,-15.115618705749512 -1312,1312,I93E,0.072400746,0.06856923200000001,0.077051975,-1.162497981,-2.328514781,0.09694108,0.10010451,0.044696981,-0.058727919,0.092668185,0.044470277999999995,0.02165553,0.13244842,-0.9904019409999999,-1.334594021,-1.974783212,-2.682246349,2.198145596,1.546592358,-8.761174513,-8.320303711000001,-8.554023642999999,-9.523994415,-10.01853043,-7.38902037,-6.59492293,-5.522805684,-14.805360794067383,-16.01308822631836,-13.707728385925293,-15.335976600646973,-15.280923843383789 -1313,1313,I93D,0.028726936,0.01416216,-1.377755769,-2.2626174519999998,-2.531716041,0.110353058,0.084568141,-0.027114269,-0.139577949,0.004039978,0.024284341,-1.465437934,-1.290073603,-2.439537364,-2.085697539,-2.15047216,-2.9129599219999998,0.625080795,0.040648933,-11.52578346,-11.55407478,-11.22533471,-12.99248003,-12.30706837,-9.549959427000001,-9.516183876,-9.435356602999999,-15.714356422424316,-16.469484329223633,-15.655250549316406,-16.75035285949707,-16.21391487121582 -1314,1314,I93G,-0.004848768,-0.022762212,-1.229219581,-2.067411457,-2.332829497,0.136786919,0.03135761,-0.041055145,-0.050965399,0.040220707,-0.08574513,-1.282531815,-1.175907347,-2.148848201,-1.985974712,-2.429658306,-2.2360006869999998,0.5567988460000001,0.06545246,-10.77337692,-10.97244062,-10.52698385,-11.06027406,-11.81401947,-9.493166602999999,-9.255026632,-8.254351544,-16.357967376708984,-15.847667694091797,-15.454038619995117,-16.37911033630371,-15.438480377197266 -1315,1315,I93F,-0.011748797,0.013327,0.033332611,-0.12712098900000002,-1.9054200190000001,0.09633873800000001,0.009264731,-0.032762325,-0.073932492,0.142342676,-0.11568867699999999,0.085663374,-0.018998153,-0.022148717000000002,-0.23209326,-1.43551405,-2.375325988,0.463041086,1.311064338,-6.452957467999999,-6.4207013239999995,-6.200675446,-9.425014885,-5.428243149,-4.790152534,-6.042227499,-2.775048522,-10.794707298278809,-9.648320198059082,-9.801258087158203,-10.445626258850098,-11.128853797912598 -1316,1316,I93H,0.045519467,0.11434024400000001,0.007659686999999999,-0.719483179,-1.8746203209999999,0.112818824,0.111875184,-0.020836251,-0.08040633700000001,0.131358416,0.097322072,-0.071745673,0.087065046,-0.327212319,-1.111754039,-2.19043546,-1.5588051809999999,1.381604574,1.307700142,-9.286875352000001,-9.930239143,-8.664343536,-11.59463589,-8.737560692,-7.507597504,-7.022177961000001,-3.551168362,-14.52629566192627,-14.790434837341309,-14.538662910461426,-15.632621765136719,-14.944517135620117 -1317,1317,I93K,0.0067833680000000006,0.103103494,0.074804032,-1.603699318,-2.628070413,0.07130597400000001,0.047476304000000004,-0.033909569,-0.038375831,0.132706587,0.07350040099999999,0.073856583,0.075751481,-1.329644755,-1.87775388,-2.295852057,-2.9602887680000003,0.76053415,0.723942538,-8.768377151000001,-8.875477242,-8.32100502,-9.003940361,-9.541783668999999,-8.099679466,-7.201274764,-5.522805716000001,-14.47113037109375,-15.086298942565918,-13.969985961914062,-15.10963249206543,-13.691254615783691 -1318,1318,I93M,0.03931536,0.053784667,0.060687749000000006,0.011312835,-0.198821455,0.117997346,0.050258432,0.028372287000000003,0.042085322,0.078033344,0.029535989,-0.024904236,0.146279734,-0.06331343099999999,0.08593910099999999,-0.219405253,-0.178237657,1.472246367,2.14117482,-4.558236092,-4.447794334,-4.453969528,-5.228156578,-4.443018257,-4.21824176,-5.106339411,-2.9185400789999996,-9.463115692138672,-9.689813613891602,-9.618688583374023,-9.125932693481445,-9.012284278869629 -1319,1319,I93L,0.063543481,0.068265429,0.056439040999999995,-0.018117044,0.009083016999999999,0.039754894,0.068267908,0.058819052999999996,-0.03133549,0.097250799,0.039280058,-0.003007744,0.115885825,-0.093452089,0.057218001,-0.027125582999999998,0.045291617,1.338492354,2.571581711,-2.98749124,-2.894065186,-2.585184685,-4.239575188,-2.60090744,-2.617723701,-3.466693802,-0.5822785189999999,-6.7272257804870605,-7.75190544128418,-7.551074028015137,-7.775505065917969,-6.706403732299805 -1320,1320,I93N,0.108282202,0.146553253,-0.043318315999999996,-1.5634569040000001,-1.829985674,-0.000315506,0.112799543,0.10376486,-0.092124879,0.175722118,0.117384388,0.0038420309999999997,-0.09047866199999999,-1.737943215,-1.388970592,-2.227029262,-1.432942085,-0.170565839,0.668172263,-9.981471383999999,-10.30947153,-9.896378754,-11.26279074,-10.42028214,-8.018433762,-7.921620836000001,-6.027269842999999,-15.07162094116211,-14.4166259765625,-14.53296947479248,-14.15300178527832,-13.878690719604492 -1321,1321,I93Q,0.01416945,0.057008333,0.077859708,-0.313567194,-1.654153896,0.074734333,0.028830527,-0.000491628,-0.085356921,0.11078349400000001,0.0032331720000000003,0.048778025,0.106941391,-0.22275721899999998,-0.40437716799999995,-1.8715441080000002,-1.4367636830000001,1.1336854090000001,1.327333361,-9.09600806,-8.681132202,-8.67726754,-10.04222624,-9.799269942999999,-8.280144371,-6.8069016410000005,-5.503169431,-13.967520713806152,-15.080978393554688,-13.685315132141113,-14.527063369750977,-13.785355567932129 -1322,1322,I93P,0.040158812,0.088148172,-0.890884166,-1.716071084,-2.827592355,0.168781199,0.086552354,-0.006234730999999999,-0.082824393,0.064160244,0.11213610000000002,-0.848203376,-0.9335649559999999,-1.5378720730000002,-1.894270095,-2.59122955,-3.063955159,2.333422203,1.198497118,-10.37183423,-10.59605161,-10.01594638,-11.26768307,-10.9713285,-9.008161583,-8.530182233,-6.959227195,-12.99836540222168,-13.929936408996582,-13.226900100708008,-14.345354080200195,-16.100666046142578 -1323,1323,I93S,0.00228312,0.052066459,-0.137030074,-1.547728334,-2.278966567,0.07369431,0.028544795,-0.023978555,-0.03053551,0.066374037,0.03775888,-0.068640522,-0.20541962600000002,-1.456917159,-1.638539508,-2.122094465,-2.435838668,1.366828481,0.7874784459999999,-8.013927866,-7.815535835,-8.566603958,-8.054255066,-9.783204269,-5.8500401989999995,-6.752208475,-5.511046595,-13.536136627197266,-14.033842086791992,-13.722633361816406,-14.514595031738281,-12.77570629119873 -1324,1324,I93R,0.027995575,0.057986145,-0.044404622000000005,-1.508261534,-2.473268585,0.141295561,0.076347862,-0.020356712,-0.048621954,0.083482926,0.032489363,-0.031063759,-0.057745485,-1.43067549,-1.585847578,-2.372059207,-2.574477963,0.867607538,0.722918527,-8.680274438,-9.236244316,-7.7256719060000005,-9.846821228,-8.778345512000001,-7.81428923,-6.295281675,-3.772880839,-13.995004653930664,-14.468622207641602,-14.141508102416992,-15.224608421325684,-14.947229385375977 -1325,1325,I93T,0.056943104,0.077423485,0.055443864,-0.68674362,-1.958171757,0.058535812,0.107611581,0.006274627,-0.12835033699999998,0.07354295200000001,0.081304017,-0.00295154,0.113839267,-0.40184751700000004,-0.971639722,-1.770111393,-2.146232121,1.5816353330000001,1.4128870359999999,-5.857366466,-5.74448484,-6.051652214,-5.074427765,-7.918670326,-4.497597183,-5.00545612,-3.518235515,-11.780265808105469,-11.469970703125,-10.733616828918457,-10.885196685791016,-10.837284088134766 -1326,1326,I93W,0.017348563,0.048124676,0.04764816400000001,-1.3505065330000001,-2.628955372,0.008206831,0.055587665999999994,-0.020890541000000002,-0.069299268,0.08245324,0.013796111000000002,0.015292881000000001,0.080003447,-1.415943206,-1.285069859,-2.683180503,-2.57473024,0.6345527879999999,0.707012973,-9.209098218,-9.214653893,-8.855229117999999,-11.46576144,-8.917599518,-7.592247116,-7.201778448,-4.9881197230000005,-15.308307647705078,-15.76225757598877,-14.286439895629883,-15.856735229492188,-15.439763069152832 -1327,1327,I93V,0.064060271,0.069159089,0.05623637099999999,0.013388793000000001,0.051135263,0.087801151,0.070496317,0.057624224,-0.11981775900000001,0.077962296,0.06035588099999999,0.026154548,0.086318194,-0.062788396,0.08956598199999999,-0.013923323999999999,0.116193849,1.1590111090000002,2.468212931,-1.252095132,-1.166196327,-1.046139633,-1.506374168,-1.791257851,-0.7505076829999999,-3.091617779,0.041563895,-5.819467544555664,-5.598318099975586,-4.046118259429932,-5.072766304016113,-5.7026753425598145 -1328,1328,I93Y,0.014565831000000001,0.10875777699999999,0.040259686,-0.010597841,-1.934341136,0.090951722,-0.016730135,0.045861797,-0.135489231,0.083951745,0.133563808,-0.048636582000000005,0.12915595400000002,-0.021939872000000003,0.00074419,-1.2727867529999999,-2.595895519,0.659395373,1.330672208,-8.123172527000001,-8.55922361,-7.811484397999999,-11.64892598,-6.618354515,-5.97787413,-6.369696619,-2.334561872,-13.333768844604492,-13.54327392578125,-12.774083137512207,-13.500494956970215,-14.553433418273926 -1329,1329,H94A,0.008190886999999999,-0.020863358999999998,0.006116085,-0.035357604,-0.08015141,0.024509881,0.006654876999999999,0.009726896,0.006926339,-0.066661521,0.024934803999999998,-0.050348388,0.062580557,-0.035545391,-0.035169817,-0.138987189,-0.021315631,1.271341103,2.12557449,0.047161813,0.292483521,-0.669142799,0.022370888,-0.738123199,1.3282206570000001,-2.070580143,-0.28510435100000003,-7.997310638427734,-7.643579959869385,-5.81205940246582,-6.406136989593506,-6.932245254516602 -1330,1330,H94C,-0.0062728459999999995,-0.038981483,-0.01146102,-0.01472634,-1.083906813,0.10447131,0.027173059,-0.03971875,-0.005016273,-0.033550259,-0.044412705999999996,-0.069788868,0.046866828,-0.022917418,-0.006535261999999999,-0.94034963,-1.227463995,0.86562072,1.389362405,-3.5628570789999996,-3.4369661639999998,-3.721215935,-4.193056969,-3.7597175519999997,-2.7033287739999996,-5.498467096000001,-3.609585763,-9.181391716003418,-10.518258094787598,-8.45082950592041,-9.069555282592773,-10.322928428649902 -1331,1331,H94E,0.040966153,-0.001807475,-0.038732702,-0.004739744000000001,-0.062243135,-0.071911772,0.031963845,0.04996846,-0.022360038,-0.040554013,0.036939063,-0.086107606,0.008642203000000001,-0.036395111,0.026915624,-0.09321819099999999,-0.031268078,1.315768198,2.266309884,-0.292440047,0.026749672000000002,-0.9881182479999999,-0.809830536,-0.901876083,1.210874962,-2.8642833710000004,-0.327817181,-9.471243858337402,-9.2461576461792,-6.668169975280762,-7.2865071296691895,-8.966821670532227 -1332,1332,H94D,0.041547262,-0.02301181,0.000617414,-0.053304147,-0.218190842,0.061392477,0.040862874,0.042231649,-0.007345121,-0.113894275,0.067870655,-0.070951638,0.072186465,-0.112196537,0.0055882430000000006,-0.28989363,-0.146488054,1.5302206180000002,2.062997791,-1.665114725,-1.661470276,-2.845548897,-1.6289506,-2.458661949,0.269058098,-3.660682385,-1.427719265,-9.535799026489258,-9.4993896484375,-6.808441162109375,-7.733589172363281,-8.689306259155273 -1333,1333,H94G,0.032364871,-0.026073076,-0.006642724,-0.032364749,-0.283787057,0.022033719,0.047526147000000005,0.017203595,-0.011402526000000001,-0.030579997,-0.021566154,-0.055186444,0.041900997,-0.062420144000000004,-0.002309353,-0.276372923,-0.29120119,1.597199518,2.143681705,-1.436057375,-1.62010498,-2.0999814530000003,-0.73204657,-2.582020714,-0.146133156,-3.0300912710000003,-2.375201654,-9.14285945892334,-9.134987831115723,-7.060610771179199,-7.613247394561768,-7.376340389251709 -1334,1334,H94F,0.037794486,-0.033495889,-0.012454825,-0.004578771,-0.050553047999999996,0.0018111610000000002,0.022443431,0.053145541,-0.012194343,-0.072943816,0.005952038000000001,-0.072350848,0.047441198,-0.034031106,0.024873565,-0.12200838,0.020902285,1.286626118,2.174956232,-2.283855458,-2.1753368230000003,-2.965018158,-2.653693199,-1.467953545,-2.157275566,-4.04540057,-0.9992813979999999,-7.796194553375244,-5.806905746459961,-6.553792476654053,-5.265933990478516,-7.081823348999023 -1335,1335,H94I,0.023113707999999997,-0.082947921,-0.045549782000000004,-0.032439172999999995,-0.073751089,-0.051684783,0.022116369,0.024111047000000004,-0.001645049,-0.0684182,-0.09747764099999999,-0.042508902,-0.048590662,-0.064440235,-0.000438111,-0.097129853,-0.050372324,1.3582868559999999,2.328034385,-1.350378624,-1.012150055,-1.150470863,-2.0996764530000003,-1.955564606,-0.534031143,-3.387062826,-0.9601009,-7.200741291046143,-7.976345062255859,-6.23448371887207,-5.685983657836914,-5.638725280761719 -1336,1336,H94K,0.063329593,-0.028654479,-0.022433307000000003,-0.0051524529999999995,0.006742309,-0.029457987999999997,0.049769602,0.076889584,-0.011331303000000001,-0.079263045,0.021954087999999997,-0.082003335,0.037136721,-0.042852363,0.032547457,-0.044049492999999995,0.057534111,1.377425088,2.400084896,0.6206935029999999,0.740410751,1.2992620240000001,0.302712112,-0.6276424939999999,1.388725121,-1.049212673,-0.504089911,-6.608973026275635,-7.741142749786377,-5.179363250732422,-5.604971885681152,-6.901523113250732 -1337,1337,H94M,0.092507305,-0.049155555,0.040542876,0.012545546000000001,-0.035634476,-0.047752776,0.094126654,0.090887955,-0.018930008999999998,-0.074330682,-0.023980427000000002,-0.062272497,0.143358249,-0.056641755,0.081732846,-0.10421939,0.032950438,1.2749308609999999,2.193197056,-1.20655701,-1.340002357,-1.081312401,-1.420315895,-1.66887516,-0.522279236,-2.72030051,-2.029179644,-9.756601333618164,-8.960665702819824,-7.779980659484863,-7.299929141998291,-7.36076545715332 -1338,1338,H94L,0.041418817999999996,-0.021860262999999998,0.019448253999999998,0.014861906000000001,-0.031465014,-0.019384134,0.041373533,0.041464102999999995,0.051710045999999996,-0.015151543,-0.028568982000000003,-0.02530835,0.064204857,-0.002358339,0.032082151,-0.04215052,-0.020779508000000002,1.312288508,2.527666673,-0.583149619,-0.733327728,-0.729720123,-1.2564071959999998,-0.41727338399999997,0.220980339,-2.404641127,-0.456164521,-7.266568183898926,-7.421591281890869,-6.401029586791992,-5.809648036956787,-6.216165542602539 -1339,1339,H94N,0.04967761,-0.06463203599999999,-0.019856274,-0.034212868,-0.121656165,-0.020537062,0.06190845,0.037446769,-0.027623991,-0.082529514,-0.046734557999999995,-0.091712368,0.051999820999999995,-0.095499939,0.027074203999999998,-0.132913618,-0.110398711,1.496222659,2.296015638,-1.5956077480000002,-1.595626671,-1.6900335690000001,-1.644319237,-2.246903191,-0.801156075,-3.0831086869999997,-2.30969854,-7.674574851989746,-7.654252529144287,-5.369982719421387,-5.8574700355529785,-5.665332317352295 -1340,1340,H94Q,0.026126791,0.01638219,-0.0068709190000000005,0.027865102000000003,-0.014702428,0.028827756,0.037893718,0.014359863,0.076341206,-0.046058588,0.078822968,-0.043849414,0.030107577000000003,0.002618206,0.053111998,-0.078093573,0.048688718,1.261419158,2.299702064,-0.001219711,0.253184029,0.492977051,-0.359717712,-0.866521164,0.47397924,-1.754796976,-1.4163905069999998,-7.01235294342041,-6.7265496253967285,-5.597297191619873,-5.6949262619018555,-6.640594005584717 -1341,1341,H94P,0.012941107,-0.032037707,-0.027974991,-0.030031462000000002,-0.530404004,-0.030228652,0.036896754,-0.01101454,-0.033298468,-0.053529065,-0.010546348999999998,-0.07458868,0.018638698999999998,-0.046142717,-0.013920206999999999,-0.470286975,-0.5905210329999999,1.403902652,1.78580415,0.326791032,0.735918167,0.166367188,-0.587603119,-0.436643021,1.7559159469999999,-2.248804732,0.27320843,-7.791626453399658,-7.476605415344238,-6.113121509552002,-6.938753604888916,-7.6556477546691895 -1342,1342,H94S,0.061998537,-0.016005265,0.031098896,-0.0013455989999999998,-0.055668842,-0.010948113,0.07695727200000001,0.047039802,0.0054464859999999995,-0.027944637999999997,-0.004065892,-0.025227002999999998,0.087424794,-0.023954324,0.021263126,-0.09570210900000001,-0.015635574,1.538479399,2.493472418,0.216786093,0.741620232,0.15094841,-0.296599609,-0.49626318399999997,0.9842246170000001,-1.9594363609999998,-0.462944541,-6.7679009437561035,-6.705542087554932,-5.092472553253174,-5.199477195739746,-5.844063758850098 -1343,1343,H94R,0.040591989,-0.045977258,0.007388863000000001,-0.002736263,-0.03804817,-0.01629592,0.043076134,0.038107842999999995,0.020170616000000002,-0.046142014,-0.045812501,-0.039603605,0.054381331,-0.025310362000000003,0.019837837,-0.03844372,-0.037652619,1.457469271,2.677032327,0.842006409,0.83183326,0.819648232,1.222389809,-0.188577705,1.524738449,-1.738058654,0.602780536,-4.192794322967529,-5.625681400299072,-4.388888359069824,-4.088481903076172,-5.1725335121154785 -1344,1344,H94T,0.02456609,-0.029347339,-0.014421746000000001,-0.022744182999999998,-0.049445233,0.041544952999999996,0.064000112,-0.014867933,-0.021558775,-0.046355633,-0.012339043999999999,-0.069368923,0.040525431,-0.037296703,-0.008191661999999999,-0.067247696,-0.03164277,1.349209593,2.375209477,1.072623405,1.745396797,0.9445404890000001,0.627955826,0.025415955,2.019807961,-1.229417635,1.200727691,-6.062493801116943,-5.640720367431641,-4.324570178985596,-5.146152496337891,-4.037744522094727 -1345,1345,H94W,0.066036861,0.00686067,0.020244798,0.0065371809999999995,-0.00306571,-0.041853529,0.053395032,0.07867868900000001,0.040661334,-0.020087594,0.033808934,-0.049201088,0.089690684,-0.046324162,0.059398522999999995,-0.05942961,0.053298190999999995,1.491416527,2.5203701780000003,-4.509281258,-4.436768501,-5.147528625,-4.8701551510000005,-4.262458908,-3.829495102,-5.381376577,-4.1917987519999995,-9.064383506774902,-10.553424835205078,-8.802462577819824,-6.246090412139893,-9.516602516174316 -1346,1346,H94V,-0.000159244,-0.058362327,-0.009146795,-0.021079719,-0.046366569,-0.012798674,0.005811352,-0.006129839000000001,-0.026702927999999997,-0.082234321,-0.034490333,-0.09333931,0.07504572,-0.042387057,0.00022762,-0.113231241,0.020498103,1.494608538,2.298426105,-0.489853593,0.120786804,-0.347753159,-1.272592705,-1.344590912,0.394882004,-2.670859345,0.110766067,-6.968258380889893,-7.504262924194336,-5.605384826660156,-5.541801929473877,-6.295551300048828 -1347,1347,H94Y,0.067546288,-0.038803866,0.000900588,-0.000901168,-0.046653887000000005,0.014666668999999998,0.084896931,0.050195644000000005,0.10696536599999999,-0.055723642999999996,-0.021884089,-0.041176998,0.042978173,-0.028474837000000003,0.026672501,-0.080862163,-0.01244561,1.1815966359999999,2.202629343,-2.45,-2.492919884,-3.442111877,-2.680290672,-1.3748181000000002,-2.259859467,-3.7761251989999995,-1.5416829380000001,-7.110814571380615,-6.117399215698242,-6.442843437194824,-5.1992974281311035,-6.90830659866333 -1348,1348,Y95A,-0.08770083599999999,-0.056902574000000004,-0.010219716,-1.6140289140000001,-2.335377871,0.002360637,-0.072638544,-0.102763127,-0.050580047,-0.015841525,-0.09796362199999999,-0.015841525,-0.004597906,-1.226193492,-2.001864336,-2.212873844,-2.457881897,0.7505663459999999,0.733658349,-12.08303249,-11.61021188,-11.68103632,-12.13920632,-13.6549644,-11.32974354,-6.711502198,-3.3058962,-14.675394058227539,-14.66610336303711,-12.45773696899414,-11.237265586853027,-15.358954429626465 -1349,1349,Y95C,-0.07032269,-0.037206404,-0.360385767,-1.423772185,-1.6466430459999999,0.023619643,-0.050988347999999996,-0.089657031,-0.070934073,-0.02725733,-0.047155478,-0.24289109,-0.477880443,-1.5777914169999998,-1.269752952,-2.5064798219999997,-0.7868062690000001,1.339068178,0.774209275,-11.02826976,-11.38453505,-11.03307596,-10.56766299,-12.54632819,-9.609746605,-7.669257562,-4.246166911,-11.663293838500977,-11.225685119628906,-10.529651641845703,-9.46579360961914,-14.289186477661133 -1350,1350,Y95E,-0.100184817,-0.298628637,-1.6119275180000001,-2.420311099,-2.4014968580000002,-0.065607745,-0.077015184,-0.123354449,-0.047349562000000005,-0.037981195,-0.559276079,-1.758140499,-1.465714536,-1.971215324,-2.8694068739999996,-2.355835685,-2.447158031,0.645593292,-0.022441454,-12.76149944,-13.17594809,-12.41757231,-12.35140285,-14.44701604,-11.4155579,-8.390911727999999,-5.677633867000001,-15.878682136535645,-17.37478256225586,-14.491120338439941,-15.279133796691895,-17.22229766845703 -1351,1351,Y95D,-0.08025339,-0.5247549970000001,-2.239953082,-2.3209142330000003,-2.540660619,-0.14063647599999998,-0.050835270999999994,-0.109671508,-0.031612256,-0.404849884,-0.644660109,-1.804955955,-2.6749502080000003,-1.841939521,-2.7998889439999997,-2.101621145,-2.979700093,4.229718639,2.462807461,-12.51202077,-12.84462182,-11.97595287,-11.9550758,-14.22686337,-11.55758999,-8.27892695,-6.073940624,-14.183751106262207,-15.920059204101562,-13.014900207519531,-14.483589172363281,-16.45316505432129 -1352,1352,Y95G,0.035023855,0.010731825,-0.043230041,-1.285856915,-2.275559344,-0.042499969000000005,0.054304690999999995,0.015743018,-0.068450148,-0.010964017,0.032427667,-0.067196065,-0.019264016999999998,-1.5107198119999998,-1.060994018,-2.117188922,-2.433929766,0.644768291,0.702607311,-13.88728156,-14.04757825,-13.78844032,-13.712131,-15.48557522,-12.40268303,-9.077273115,-6.735138178,-16.831035614013672,-16.260875701904297,-15.040864944458008,-14.64372444152832,-16.617015838623047 -1353,1353,Y95F,0.005928239,-0.007574703,-0.016208142,0.015282266000000001,0.001701839,-0.016869733999999997,-0.029046564,0.040903042,-0.024569602000000003,-0.010336963000000001,-0.004812443,-0.022995328,-0.009420956,-0.010553191000000002,0.041117722,-0.012374649,0.015778326000000002,1.089169871,2.4203885019999998,-2.403114738,-2.027114235,-2.409318344,-3.4846364060000004,-2.069448074,-2.025056633,-2.693370883,-1.169213456,-6.926619052886963,-5.799124717712402,-4.854296684265137,-6.217315673828125,-7.437371253967285 -1354,1354,Y95I,-0.057234797999999996,-0.033562878,-0.011516266,-0.031686492999999996,-0.08484952,-0.027164544,-0.113849009,-0.0006205869999999999,-0.076801332,-0.070236964,0.003111208,-0.087749879,0.06471734700000001,-0.028363264,-0.035009721,-0.177103583,0.007404544,1.506929334,2.209819059,-5.495317018,-5.690044769,-5.1216605,-5.751103546,-7.679687927000001,-3.2340883480000002,-3.2051527710000003,-0.129919317,-11.369611740112305,-10.044294357299805,-8.59583568572998,-6.214285373687744,-8.824281692504883 -1355,1355,Y95H,-0.09176343699999999,-0.002226713,-0.015098083,-0.692949887,-1.783828991,0.018856915,-0.09293572900000001,-0.090591145,-0.037039529,0.045763607000000005,-0.050217033,0.00483025,-0.035026416,-0.337533543,-1.04836623,-1.7492121369999998,-1.818445845,1.463858041,1.391535989,-9.28082283,-10.07584953,-9.245530457000001,-8.874613678,-10.03448234,-8.173638145,-8.422618133,-6.73301239,-11.157605171203613,-9.77784538269043,-9.51552963256836,-10.687461853027344,-12.16089916229248 -1356,1356,Y95K,-0.192380133,-0.233460229,-1.429617359,-2.178474562,-2.6992509439999997,0.024596145,-0.13998867199999998,-0.244771593,0.029889615,-0.062946426,-0.40397403200000004,-1.27246144,-1.5867732769999998,-2.309445007,-2.047504116,-2.393035372,-3.005466515,0.9061017640000001,0.103353275,-13.31574802,-13.79023117,-13.41114806,-12.97895482,-15.35274277,-11.04566329,-9.840817797,-9.092961316,-16.023508071899414,-16.073083877563477,-14.807766914367676,-13.190710067749023,-18.180522918701172 -1357,1357,Y95M,0.000388289,0.030030351,0.03807319,0.027107456000000002,-1.705062055,-0.08241757200000001,-0.002509281,0.0032858590000000003,-0.008644679,0.022011048999999998,0.038049652,0.019063813,0.057082567,-0.031653529,0.08586844099999999,-1.432261995,-1.9778621140000001,0.6683473010000001,1.322520938,-10.08700448,-10.32920718,-10.53441329,-10.36062302,-11.61988777,-7.590891136000001,-6.439095646,-1.998974396,-13.885747909545898,-13.600887298583984,-11.01393985748291,-10.262856483459473,-14.25278091430664 -1358,1358,Y95L,-0.09639272800000001,-0.026333412999999996,-0.029250362000000002,-0.028171676,-0.912806239,-0.011345718999999999,-0.140664863,-0.052120593,-0.11341301,-0.00274069,-0.049926135,-0.027073267999999998,-0.031427455,-0.038334513,-0.018008839,-0.630697481,-1.194914997,1.135663083,1.551840374,-7.468680336,-7.9718515089999995,-8.193439468,-7.425380211,-8.127531685,-5.625198807,-4.455425847,-0.259887795,-10.853949546813965,-11.527761459350586,-8.899557113647461,-8.636199951171875,-12.172576904296875 -1359,1359,Y95N,-0.13292859199999998,-0.11501768,-1.163358974,-2.2025470990000002,-2.6352778519999998,-0.165013877,-0.078323583,-0.18753360100000002,-0.07933708,-0.008383079,-0.221652281,-1.179510918,-1.147207029,-1.956857174,-2.448237024,-2.341477535,-2.929078169,2.359553468,0.858233032,-12.6706176,-13.18340276,-12.96967202,-11.91582143,-14.58191129,-10.702280499999999,-9.840817797,-9.092961316,-14.263571739196777,-13.780357360839844,-12.849756240844727,-12.409892082214355,-14.391839981079102 -1360,1360,Y95Q,0.08154850599999999,0.07368965400000001,-1.090896945,-2.04595211,-2.5667284919999998,-0.07313425700000001,0.08045470099999999,0.082642311,-0.102863279,0.063636787,0.08374252,-1.208743621,-0.973050269,-1.9147339680000002,-2.177170252,-2.174415592,-2.959041392,4.019261089,2.568060487,-12.38382109,-12.90495104,-12.35305533,-11.80426182,-14.68496329,-10.17187396,-8.245324832,-5.394011011,-14.436287879943848,-14.855203628540039,-13.517457962036133,-13.608728408813477,-15.859582901000977 -1361,1361,Y95P,-0.05235467,-0.026495532999999998,-0.014449066000000002,-0.905083713,-1.99029461,-0.06386315599999999,-0.053248147,-0.051461192999999995,-0.072198277,0.005596154,-0.05858722,-0.028607452000000002,-0.00029068,-0.671360686,-1.138806739,-1.8341322969999998,-2.146456922,1.995406414,1.530036062,-13.01048665,-12.99487713,-13.05487712,-12.76651793,-14.6343652,-11.60179586,-7.847034962,-4.3884507180000005,-16.517053604125977,-15.264532089233398,-13.158231735229492,-14.808629035949707,-16.942424774169922 -1362,1362,Y95S,-0.083270224,-0.055407662,-0.587803647,-1.5690730659999998,-2.125006547,-0.038202556,-0.072605052,-0.093935395,-0.09395777599999999,-0.018113951,-0.09270137199999999,-0.47644416,-0.6991631340000001,-1.5092044080000002,-1.6289417240000001,-2.607035212,-1.6429778819999998,1.939070296,1.010307579,-12.21303193,-12.23193242,-12.49315088,-11.19453429,-14.51744859,-10.62809349,-7.6632821689999995,-4.590043145,-14.22846794128418,-13.951017379760742,-12.924942970275879,-12.96636962890625,-14.52888011932373 -1363,1363,Y95R,-0.045848397,-0.179156531,-1.238506919,-1.8063884069999998,-2.553313625,0.001810866,-0.009860319000000001,-0.081836474,-0.07941764700000001,-0.090343699,-0.267969362,-1.478571321,-0.9984425159999999,-2.328468244,-1.28430857,-3.0141186,-2.092508649,0.88203872,0.057384285,-11.44093877,-12.26467865,-11.90285524,-10.6346306,-13.54481596,-8.857713417000001,-7.731617653,-5.173065343,-15.227100372314453,-14.35800552368164,-13.002840042114258,-13.089984893798828,-15.88064956665039 -1364,1364,Y95T,-0.088938583,-0.014400066999999999,-0.09982331400000001,-1.55997798,-2.673178912,-0.016199543,-0.07878269,-0.099094476,-0.067801809,0.036241595,-0.065041729,-0.061332223,-0.138314405,-1.237033882,-1.8829220780000002,-2.599377848,-2.746979975,0.830698865,0.7381664490000001,-12.16538674,-11.96817904,-12.19053334,-12.460484800000001,-13.83311046,-10.37462605,-7.114778026000001,-4.2839290189999994,-15.209547996520996,-14.282339096069336,-12.593656539916992,-11.458319664001465,-14.800747871398926 -1365,1365,Y95W,-0.021560606,0.049847117999999996,0.020868366,0.017810347,-0.029609705,-0.099855594,-0.010881095,-0.032240117,0.0263474,0.119372104,-0.019677868,0.016858213,0.024878518999999998,0.026195791,0.009424901999999999,-0.000460077,-0.058759333,1.18511676,2.704507312,-5.057599092,-5.5070110020000005,-6.810774857,-3.9720291210000003,-4.213856903,-4.784323578,-4.415219438,-2.190172783,-9.331012725830078,-10.048731803894043,-6.825297832489014,-9.00358772277832,-9.795160293579102 -1366,1366,Y95V,-0.061207329000000005,-0.054609064000000006,-0.002049376,-0.049316092,-1.178690744,-0.014840672,-0.123815885,0.0014012270000000001,-0.031122876,-0.049768318,-0.05944981,-0.08185119,0.077752439,-0.10255952199999999,0.003927339,-0.8290039490000001,-1.528377539,1.498939425,1.6588226830000001,-6.557820639,-6.385235778999999,-6.959621147000001,-6.057320824,-8.014536346,-5.372389098999999,-5.021173484,-0.148963985,-12.199294090270996,-12.094590187072754,-9.49570083618164,-7.207823753356934,-11.186037063598633 -1367,1367,S96A,-0.001867401,0.007803929,-0.01046151,0.011749338,-0.0036420640000000004,-0.038081264,-0.010412741,0.006677939,-0.216419998,-0.017897031,0.033504888,-0.040004224,0.019081205,-0.007493279,0.030991954,-0.01973517,0.012451041999999999,1.2088107909999999,2.514666621,-1.278011378,-1.293539932,-1.420447662,-0.722442734,-1.509714279,-1.443912285,-2.726487498,-0.7087993440000001,-3.8123128414154053,-4.033059120178223,-2.933382987976074,-5.4076056480407715,-6.0746750831604 -1368,1368,S96C,-0.053363309000000005,-0.035995551,-0.048848929000000006,-0.046647174000000007,-0.716253046,0.101406944,-0.024722571000000002,-0.082004047,-0.617820539,0.008825614,-0.080816715,-0.05911371,-0.038584147,-0.044005808,-0.04928854,-0.44818847700000003,-0.984317615,1.571618666,1.942024772,-4.61375347,-5.061775848,-4.6426067810000005,-4.803973343,-4.332905289,-4.227506088,-6.280401984,-4.015016151,-7.865070343017578,-9.437254905700684,-7.96898889541626,-9.096461296081543,-10.555745124816895 -1369,1369,S96E,-0.030868378,0.009039941999999999,-0.016716492,-0.027475466,0.0282327,0.014722289,-0.030302087999999998,-0.031434667,-0.061518038,0.031165312999999997,-0.01308543,0.013430283000000001,-0.046863267,0.011707883,-0.066658815,0.038965889,0.01749951,1.12939296,2.644671853,-1.3965868190000001,-2.301422638,-1.530477394,-1.0740489579999999,-1.034952988,-1.04203212,-2.544063136,-0.46843668899999996,-5.501601219177246,-5.104524612426758,-4.458855628967285,-6.438757419586182,-6.852286338806152 -1370,1370,S96D,-0.049874941,0.008320542,-0.020242917,-0.049817663,-0.00321986,0.007999055,-0.034312307,-0.065437575,-0.36254803399999996,0.043622865,-0.026981781,-0.00036753,-0.040118303,-0.026186968999999997,-0.073448357,0.010053191999999999,-0.016492912,1.210836264,2.5589565640000003,-1.4443152559999999,-2.52507412,-0.7499836040000001,-1.977412346,-1.376665375,-0.592440834,-2.8824057389999997,-0.38179571,-5.4729084968566895,-6.882265090942383,-5.232016086578369,-6.891045093536377,-7.406335830688477 -1371,1371,S96G,-0.024905311,0.015297998,-0.001027734,0.005783417,0.037468031,0.013475941000000002,-0.030233523999999998,-0.019577096999999998,-0.232214265,0.032033048,-0.001437052,-0.008812105,0.006756638000000001,0.000484195,0.011082638,0.011110306,0.063825755,1.192579612,2.685602053,-0.744863864,-0.44022361,-0.795572701,-0.319081093,-2.062609932,-0.106831985,-2.994770781,-0.42199711100000004,-4.393540859222412,-3.5038609504699707,-4.782866954803467,-4.154661178588867,-5.071584701538086 -1372,1372,S96F,-0.015831486000000002,-0.04016404,-0.055435258,-0.015341146000000002,-0.106211683,0.022147146,0.003811732,-0.035474702999999996,-0.420539981,-0.015399876000000002,-0.064928203,-0.039660289,-0.071210226,-0.040048656,0.009366365,-0.061930484,-0.150492882,1.299251671,2.391722178,-5.899376051,-6.587656142999999,-5.2923928380000005,-6.281559357000001,-5.105053238,-6.230218681,-6.9696696739999995,-5.167124826,-7.731089115142822,-10.286850929260254,-8.339126586914062,-9.57343578338623,-10.086265563964844 -1373,1373,S96I,-0.040485662,0.034115543,-0.00927947,0.018133019,-0.08201615400000001,0.044546573,-0.047815620999999996,-0.033155702999999995,-0.304556087,0.073995701,-0.005764615,0.034263639,-0.052822579,0.016702424,0.019563613,-0.041603852999999996,-0.122428455,1.134415154,2.33787599,-4.4090651030000005,-5.1203946380000005,-4.553751411,-4.597449684,-3.9280571139999996,-3.845672668,-5.648004482,-3.5926032660000002,-7.140293598175049,-7.713062286376953,-7.202695846557617,-8.90748405456543,-8.963186264038086 -1374,1374,S96H,-0.067314641,-0.034136804,-0.01790189,-0.03643649,0.011625173,0.034795605,-0.062160685,-0.072468597,-0.119509985,-0.026564253,-0.041709354,-0.002355151,-0.033448629,-0.037422704,-0.035450275,0.00981028,0.013440066,1.25873652,2.6202942680000003,-1.879159442,-2.063759216,-1.713103065,-2.373119385,-1.433165276,-1.8126502690000001,-3.3012024889999996,-1.7201429680000002,-5.528205871582031,-6.389204978942871,-4.814507007598877,-6.76608419418335,-6.671115398406982 -1375,1375,S96K,0.011290257,-0.011418876000000001,-0.008788753,-0.016388144,-0.0023632270000000003,0.000959937,0.019289143,0.003291371,0.707489833,-0.018335268999999998,-0.004502483,0.004771081,-0.022348587000000003,-0.023109601,-0.009666685999999999,-0.019828496,0.015102042,1.255113711,2.5172336459999998,-0.511834904,-0.563582542,-0.7715997090000001,-0.752966438,-0.143220604,-0.327805229,-2.640425569,0.15467129400000001,-4.657646656036377,-2.6643176078796387,-3.9710943698883057,-4.195392608642578,-6.663008213043213 -1376,1376,S96M,-0.055335216,0.018833219,0.005462531,0.002873301,-0.0196778,0.016606521000000003,-0.05502877900000001,-0.055641653,-0.36254803399999996,0.069216344,-0.031549906,0.003985027,0.006940035,0.01127491,-0.005528308000000001,0.026697778,-0.066053377,0.9547578290000001,2.4463254880000003,-3.9639921019999997,-4.495159576,-3.657747467,-4.191444359,-3.478028625,-3.997580482,-4.976318378999999,-2.380560391,-7.938299179077148,-7.108942985534668,-7.584572792053223,-8.472899436950684,-8.57503890991211 -1377,1377,S96L,-0.01543998,0.010835811,-0.00040538099999999996,0.002699527,-0.025364385,0.03622999,-0.003850314,-0.027029646,-0.119509985,0.035085115,-0.013413494,0.01691705,-0.017727811,-0.0051692990000000005,0.010568353,-0.032215055,-0.018513714,1.206292786,2.495999607,-2.386765623,-3.526179642,-1.573074501,-2.951202126,-1.5869829709999999,-2.296388878,-4.01691176,-1.4846035640000002,-5.449120044708252,-6.802801132202148,-6.175130367279053,-6.820896148681641,-7.614577293395996 -1378,1378,S96N,-0.016254759,-0.022475986,-0.001846978,0.011931873,0.009597091,-0.01613118,-0.038361558,0.00585204,-0.324759473,-0.055259631,0.01030766,-0.035565808,0.031871852,-0.0007746210000000001,0.024638366000000002,-0.021039896000000002,0.040234078,1.543610422,3.106887046,-1.49374707,-1.8134411769999998,-1.6786697080000001,-1.946646545,-0.788955574,-1.2410223470000001,-2.3937049619999997,-1.344282278,-5.976027011871338,-5.971004962921143,-5.11404275894165,-5.739556789398193,-5.8627610206604 -1379,1379,S96Q,-0.033473393,-0.023366829,0.011022466000000002,-0.02653964,0.048938315999999996,0.039399807,-0.050603779,-0.016343006,-0.36254803399999996,0.008306374,-0.055040032,0.003805158,0.018239774,-0.033430866000000004,-0.019648413,0.020709743,0.077166889,1.2800366159999998,2.710921859,-1.316956718,-1.328183952,-1.86609082,-1.170992157,-0.7678313370000001,-1.451685326,-2.632282178,-0.84245369,-4.6407551765441895,-2.8318028450012207,-2.886326551437378,-4.716740608215332,-4.935912609100342 -1380,1380,S96P,-0.043877309,-0.0017465129999999999,-0.007789765,-0.021045379,-1.456086594,0.039891017,-0.022432009,-0.065322608,-0.033122666,0.014523593999999999,-0.018016618999999998,-0.0047095670000000004,-0.010869963,-0.0014131870000000002,-0.040677571,-1.397266294,-1.5149068940000001,0.8221191729999999,1.336818778,-2.221355354,-3.4958479839999996,-2.777946533,-1.109350533,-1.309988503,-2.413643219,-3.598775005,-0.7416274959999999,-7.023036956787109,-8.004143714904785,-6.485463619232178,-7.296289920806885,-7.885066986083984 -1381,1381,S96R,-0.028353079,-0.017692668,-0.011650031000000002,-0.021686612999999997,0.0037683190000000004,0.010297094,-0.025659188,-0.03104697,-0.178903637,-0.017893066000000003,-0.01749227,-0.024280611,0.000980549,-0.02366,-0.019713225,-0.025080646,0.032617283,1.266887541,2.476383067,0.535323428,0.349915962,0.7991299359999999,0.46397360200000004,0.396005867,0.667591774,-0.7323179479999999,0.28071299899999996,-3.084728240966797,-3.410271167755127,-4.058701038360596,-4.849404335021973,-5.742812156677246 -1382,1382,S96T,5.8599999999999995e-05,0.007634001,0.010590375,-0.020313983,0.032250079,0.014165811,0.004663629,-0.004546483,0.211483234,-0.006167469,0.021435471,-0.011753862,0.032934611,-0.016943571,-0.023684395,-0.009761289,0.07426144700000001,1.1992141440000001,2.564123395,0.250449315,0.523665321,0.131489204,0.126006721,0.299737839,0.17134748800000002,-1.233915839,0.852803525,-2.990253448486328,-2.7947006225585938,-4.119582176208496,-2.9009242057800293,-3.4741227626800537 -1383,1383,S96W,-0.051347789000000005,-0.030122277000000003,-0.022056507000000003,-0.027889759,-0.34578657,0.04836397,-0.002456749,-0.100238828,0.415603217,-0.0014744629999999999,-0.058770090999999997,-0.014290711999999999,-0.029822302000000002,-0.019028701000000002,-0.036750816,-0.279428354,-0.412144785,1.320101189,1.928781018,-6.284584436,-6.922490532,-5.555696739,-6.617023445,-5.700796767999999,-6.626914696,-7.845625234,-6.935128809,-8.801053047180176,-10.682406425476074,-10.218260765075684,-10.423816680908203,-10.6835355758667 -1384,1384,S96V,-0.05593132,-0.008019128,-0.047026306,-0.01739867,-0.031687321000000004,0.037263485,-0.040657393,-0.071205247,-0.36254803399999996,0.034222563,-0.050260818,-0.024063469,-0.069989142,0.013745425,-0.048542764,-0.010383308,-0.052991333,1.318602805,2.642984867,-3.012049365,-3.5857973710000004,-3.447556633,-2.6094522319999998,-2.649790749,-2.7676498410000003,-4.291263542,-2.008247049,-5.620657444000244,-6.424972057342529,-6.083084583282471,-7.571184158325195,-8.78377914428711 -1385,1385,S96Y,-0.083757906,-0.045405409,-0.038051755,-0.041922627999999997,-0.090141803,0.020060623,-0.066874639,-0.10064117199999999,-0.408305524,-0.023087229,-0.067723588,-0.027158032999999998,-0.048945477,-0.019377791000000002,-0.064467464,-0.09270448,-0.087579126,1.3479422719999998,2.262875996,-4.335690787,-4.712930237,-4.23008728,-4.686171599999999,-3.6429133910000004,-4.406351425,-6.231547332000001,-3.14045519,-7.7854108810424805,-9.638426780700684,-7.838291645050049,-9.456652641296387,-9.633928298950195 -1386,1386,Q97A,-0.01178375,-0.020786042,0.002297365,0.055621348,-0.019611956,0.041292018,0.025714023,-0.049281522,0.04408119,-0.019223291,-0.022348792000000003,-0.003661046,0.008255776,0.002120941,0.109121754,0.012281097,-0.051505008,1.297655796,2.712141618,-1.412247394,-0.42550209,0.19141443600000002,-2.040151443,-3.8905439989999997,-0.896453873,-2.764545019,0.873521775,-4.857351303100586,-5.54011344909668,-3.960197687149048,-5.061407089233398,-6.8007965087890625 -1387,1387,Q97C,-0.10734501199999999,-0.017768938999999997,-0.041538151,0.003076517,-1.576997734,0.16818346,-0.058892362000000004,-0.155797662,0.074331421,-0.045696012,0.010158134000000001,-0.044553978,-0.038522324,0.010978979,-0.004825945999999999,-1.5056762769999998,-1.64831919,0.7259613840000001,1.323414735,-7.32499118,-6.31143457,-6.090348145,-8.439606857000001,-9.107682457000001,-6.675883872999999,-8.386624201,-6.441058645,-9.915603637695312,-12.384586334228516,-9.010027885437012,-11.319283485412598,-12.371880531311035 -1388,1388,Q97E,-0.063623807,-0.022325637000000002,0.001899499,0.037051467000000005,0.002158724,0.081328079,-0.025164256,-0.10208335800000001,0.136780583,-0.002818989,-0.041832284,-0.016669531,0.020468529,0.009069001,0.065033932,0.022480002000000002,-0.018162555,1.269608364,2.781116593,-0.537129779,-0.058132301,0.7104683690000001,-1.2395806809999999,-1.390954323,-0.7074499590000001,-2.061800863,0.65790647,-5.3706464767456055,-7.129709243774414,-4.108707427978516,-5.925402641296387,-6.360256195068359 -1389,1389,Q97D,-0.018227653,0.044454985999999995,0.006432205999999999,0.048878659000000005,-0.002857923,0.11320185099999999,0.028509721000000002,-0.064965026,-0.001165372,0.10979243699999999,-0.020882465,0.060584266,-0.047719855,0.036189708,0.06156761,0.058075862,-0.063791707,1.198917167,2.858142857,-3.0336619519999997,-1.910598663,-1.835028305,-4.140161957,-5.095159035,-2.1873618009999998,-3.950145627,-0.029194151,-7.568325519561768,-9.637863159179688,-6.684749603271484,-8.087684631347656,-8.384604454040527 -1390,1390,Q97G,-0.046372329000000004,-0.0036467440000000004,0.012263541000000001,0.052632020999999994,-0.01401232,0.055798469,-0.025045401000000002,-0.067699257,0.017072969,-0.001533267,-0.00576022,0.0060084,0.018518681000000002,0.011893975,0.093370066,0.008296743,-0.036321383,1.543610422,3.106887046,-3.8247182860000004,-2.639819641,-2.371761444,-5.298431686,-5.702301788,-3.1112768710000003,-4.280951049,-1.53256485,-7.962394714355469,-8.698040962219238,-6.78994083404541,-7.959028720855713,-8.991325378417969 -1391,1391,Q97F,-0.027954389,0.007563676,0.018163898,0.07681640599999999,-0.075288388,0.027087037,-0.046255789000000005,-0.009652989,0.09241302900000001,0.017488493,-0.002361141,-0.000337312,0.036665107,0.046196368,0.107436444,0.01378671,-0.164363486,1.159932201,2.655793289,-6.332944406,-4.938813789,-5.4011706770000005,-7.958062126000001,-8.132553459,-5.234121979,-6.905060988,-4.037158822,-8.115432739257812,-11.757946014404297,-8.915276527404785,-10.500080108642578,-11.727876663208008 -1392,1392,Q97I,-0.082261301,-0.061406409,-0.118546134,0.000176779,-0.050842347999999996,0.08128898400000001,-0.00696037,-0.157562231,0.031813779,-0.053877924,-0.068934893,-0.09225482900000001,-0.144837439,-0.029400806,0.029754363,-0.030129816,-0.071554879,1.134089548,2.3888916890000003,-5.02927417,-3.833514175,-4.562556273999999,-6.3738156660000005,-5.956702614,-4.41978212,-6.082620241,-2.564586313,-8.015508651733398,-10.708555221557617,-6.033668518066406,-8.052791595458984,-9.558372497558594 -1393,1393,Q97H,-0.038335157,-0.005533636,-0.023930157,0.020981771,-0.091936105,0.08796825900000001,-0.008770824,-0.06789949,-0.0011158589999999999,0.004114023,-0.015181294,-0.040040721,-0.007819592,-0.025390671,0.067354213,0.020480178,-0.204352388,1.1634596990000001,2.579968909,-3.7136412930000002,-2.9960353160000004,-3.026735413,-4.551973236,-4.972199165,-3.021263336,-5.43519128,-2.250006116,-5.527899742126465,-7.227510929107666,-5.931379795074463,-6.868607521057129,-6.897870063781738 -1394,1394,Q97K,-0.126185616,-0.0007452180000000001,0.045289667,-0.031884997000000005,-0.010289612,0.037450519,-0.129459959,-0.12291127199999999,0.09017402,0.073318568,-0.074809004,0.040341418999999996,0.050237914,-0.012997924,-0.05077207,0.052986732,-0.073565955,1.098010228,2.749975142,0.155567873,0.591089355,0.723372887,-0.393737213,-0.332330948,0.189445282,-1.84543887,1.056956588,-3.187697172164917,-3.322448253631592,-1.7951226234436035,-2.8113064765930176,-4.670604705810547 -1395,1395,Q97M,-0.067446126,-0.048332581,-0.01690647,-0.017686759,-0.077931497,0.040252618999999996,-0.045920329,-0.088971922,0.045675655,-0.030906345,-0.065758817,0.029652955,-0.06346589400000001,-0.005445546999999999,-0.02992797,-0.05828730000000001,-0.097575694,1.5464736069999998,2.938183126,-4.969837845,-4.187673988,-4.469774353,-6.31179303,-6.103762741000001,-3.776185112,-5.9483184289999995,-3.0364833989999997,-8.205923080444336,-10.020352363586426,-7.0132927894592285,-8.493040084838867,-9.120002746582031 -1396,1396,Q97L,-0.028161022,-0.010277035,-0.030235466000000003,0.021141949,-0.010569208,0.021105557999999996,0.002858185,-0.059180228,0.08937674599999999,-0.0009201810000000001,-0.019633888999999998,-0.020907735,-0.039563196,-0.004544355999999999,0.04682825400000001,0.005393947,-0.026532363,1.1306588690000001,2.487209058,-4.031868669,-3.2007987289999997,-3.9090277789999996,-5.4769343720000006,-4.600824966,-2.9717575000000003,-5.63322917,-2.235617769,-7.517592906951904,-9.156764030456543,-6.365506649017334,-7.572965621948242,-8.395973205566406 -1397,1397,Q97N,-0.08405011300000001,-0.043539549000000004,-0.014466392,0.03604303,-0.09614658300000001,0.119263964,-0.0021027529999999997,-0.165997473,-0.020475915,-0.110978286,0.023899188,-0.01106775,-0.017865033,0.006619039,0.06546702,-0.051836342,-0.140456824,1.273551708,2.438066222,-3.4996937530000003,-2.47664122,-2.8199089510000004,-4.740303268,-4.479600693,-2.982014633,-4.63087206,-0.354847928,-7.315673828125,-8.869759559631348,-6.486800193786621,-6.770002841949463,-8.006296157836914 -1398,1398,Q97P,-0.05300426,-0.048890939,0.0028949270000000003,0.020299373,-0.033617087000000004,0.035344524,-0.041817999,-0.064190521,0.068123327,-0.005985857,-0.09179602099999999,-0.020155523999999998,0.025945377000000002,-0.029888355,0.07048710000000001,-0.000324686,-0.066909487,1.1391985340000002,2.4211962280000003,-1.8958555240000001,-0.49771650700000003,-0.6557459489999999,-3.69503241,-3.2205861739999997,-1.410196579,-2.74975932,0.842874219,-6.040284156799316,-8.228446960449219,-5.63039493560791,-6.8450798988342285,-7.7238616943359375 -1399,1399,Q97S,-0.038334711,-0.025954396,-0.010194942,0.057304561,-0.015191231999999999,0.045280699,0.005589508000000001,-0.08225892900000001,0.05229580599999999,-0.020424008,-0.031484784,-0.007081889,-0.013307995,0.023433189,0.09117593199999999,0.018671557,-0.04905402,1.101222184,2.6210884290000003,-2.0268087340000003,-1.14127919,-0.307115646,-3.0163728489999997,-3.629163399,-2.040112587,-3.5287744830000003,-0.265720842,-5.913804054260254,-6.690189361572266,-5.126165390014648,-6.2384185791015625,-7.5045928955078125 -1400,1400,Q97R,-0.05173822,-0.027682987000000003,-0.0057095240000000005,0.044221478,-0.025489968,0.047576151,-0.027706875,-0.075769564,0.115186463,0.010267206999999999,-0.065633181,0.007776341,-0.019195388,0.018878261,0.06956469400000001,0.022290196,-0.073270132,1.123902709,2.683513769,-0.8327057109999999,-0.634364746,-0.096529015,-1.025385788,-1.9213386609999998,-0.485910347,-2.1047231490000002,0.714424365,-3.715792417526245,-4.849137306213379,-2.9720091819763184,-4.7071709632873535,-4.91049337387085 -1401,1401,Q97T,-0.033832614,-0.026347409,-0.017490861,0.037239475,-0.032345228,0.066863271,0.003338502,-0.07100373,0.08892658699999999,-0.024937774,-0.027757043,-0.031973099,-0.0030086229999999998,-0.021786547000000003,0.09626549599999999,-0.020955939,-0.043734517,1.239348798,2.5122110980000003,-3.016581023,-1.8698046259999999,-1.635979866,-4.145479553,-4.679944023,-2.7516970439999997,-3.904692295,-1.365166625,-6.824294567108154,-7.893134593963623,-5.562679767608643,-6.469679355621338,-8.199748992919922 -1402,1402,Q97W,-0.062078337000000004,-0.049287777000000005,-0.013915967,0.007019788000000001,-0.079322043,0.048114653,-0.031138587000000002,-0.093018087,0.09688724,-0.029755155,-0.068820398,0.032161028,-0.059992962000000004,-0.025794532000000002,0.039834107,-0.043496531,-0.115147555,1.3863315019999998,2.59155476,-5.386335599,-4.313519882,-4.591717194,-6.7542219470000004,-7.144302109,-4.127916862,-6.007852069,-3.090499608,-9.0775146484375,-13.56420612335205,-9.851568222045898,-11.50839614868164,-11.37977409362793 -1403,1403,Q97V,-0.015442053999999998,0.012150015,0.008421494,0.045222625,0.021819069,0.057853798,0.01693819,-0.047822298,0.088777875,-0.0031780590000000004,0.027478087999999998,0.011111801999999999,0.005731185,0.017556313,0.072888936,0.027388016,0.016250121,1.211539417,2.7639567260000004,-3.9000154210000004,-3.017297806,-2.9981322169999998,-5.06134536,-5.525716782000001,-2.897584938,-4.732161436,-1.751594875,-6.840699195861816,-8.856422424316406,-4.908575057983398,-6.937032699584961,-8.852821350097656 -1404,1404,Q97Y,-0.09024597300000001,-0.014839268999999999,-0.045435635,0.031308355,-0.08975712300000001,0.04509579,-0.023865361,-0.156626585,-0.025854386,-0.009496026,-0.020182512,-0.004682466,-0.08618880400000001,0.00020774700000000002,0.062408963,-0.041899597000000004,-0.137614649,1.247006319,2.456622331,-6.1545489689999995,-4.610100815,-5.350209641,-7.86407605,-8.227004013,-4.721354324,-6.769203571,-4.037158725,-6.506624221801758,-11.194408416748047,-8.31745719909668,-9.94350814819336,-10.74026107788086 -1405,1405,N98A,0.004424573,-0.014009134,-0.021701758999999998,-0.036849619,-0.054690586,-0.01574315,-0.011678973999999998,0.020528118999999997,-0.221688318,0.007309899999999999,-0.035328168,-0.033964612000000005,-0.009438905,-0.042588905,-0.031110332,0.010200534,-0.119581706,1.16137238,2.560048067,0.781464713,1.2018165440000002,-0.21422881300000002,0.969553642,0.3014104,1.64877179,-1.912630785,1.984376224,-2.8957810401916504,-3.3509883880615234,-2.2445898056030273,-3.4945082664489746,-4.4504194259643555 -1406,1406,N98C,0.081171246,-0.02226127,-0.071471747,-0.143726178,-1.668090614,-0.099336077,-0.047720689000000004,0.21006318100000002,-0.059352293,-0.0016997529999999998,-0.042822787,-0.057322146,-0.08562134699999999,-0.066666433,-0.220785923,-1.563563726,-1.772617501,0.909002869,1.333090846,-4.195735045,-3.960493927,-5.020238495,-4.392549988,-4.093222969,-3.5121698460000004,-5.575185635,-2.7465093489999997,-9.759861946105957,-10.953964233398438,-8.140063285827637,-10.500892639160156,-10.58641242980957 -1407,1407,N98E,-0.060883854,-0.066025394,-0.045896015,-0.07035511400000001,-0.09112556699999999,-0.009761176,-0.098571992,-0.023195716,-0.09456552,0.003316587,-0.135367374,-0.037451164,-0.054340865,-0.070516471,-0.070193756,-0.009680459,-0.172570675,1.418178283,2.641941297,0.540609685,0.9309057079999999,0.32034845,-0.049115028,0.334837814,1.16607148,-2.394245176,1.881546436,-4.264220714569092,-5.053861141204834,-3.025677442550659,-6.132654666900635,-4.827300548553467 -1408,1408,N98D,0.021104186,-0.0022073320000000002,-0.003625583,-0.031768604,-0.031768977000000004,-0.020744895,-0.000919298,0.043127669,-0.16866724100000002,0.043963792,-0.048378455,0.010519899,-0.017771065,-0.05407826599999999,-0.009458942,0.037580881000000003,-0.101118834,1.2552481000000002,2.736244553,0.9197443390000001,0.8927578890000001,0.959958069,1.119556129,0.8409990009999999,0.785450607,-2.037772905,1.617415587,-3.2552554607391357,-4.288251876831055,-2.6902666091918945,-6.05350399017334,-3.956557273864746 -1409,1409,N98G,-0.004499332,-0.041130433,-0.031414219,-0.058506797,-0.061982212,-0.012741225,-0.029592253,0.020593589,-0.089485995,-0.029756774,-0.052504090999999996,-0.019080354,-0.043748083,-0.081964854,-0.03504874,-0.025529451,-0.098434972,1.401647666,2.585036644,-0.174039737,0.29059293399999997,-0.320846657,0.13343605,-0.88938092,-0.084000092,-2.971876762,0.906377946,-5.735315799713135,-5.734994888305664,-4.239157676696777,-6.357536315917969,-6.2742695808410645 -1410,1410,N98F,0.001768825,-0.0076999780000000006,-0.00020354099999999998,-0.034917647,-0.022139397,-0.042785635,-0.029281225,0.032818875,-0.142923736,0.005540664,-0.02094062,-0.012149763999999999,0.011742681999999999,-0.058555285,-0.011280008999999999,0.015250317,-0.05952911,1.104579495,2.627155609,-4.654500285,-3.99240062,-5.819995842000001,-4.616950424,-5.2310901869999995,-3.6120643539999997,-5.006562509,-2.311884708,-8.2250337600708,-8.91496467590332,-7.34813117980957,-9.052435874938965,-9.66356372833252 -1411,1411,N98I,0.011351267,-0.028654446,-0.017715678000000002,-0.046885397999999995,-0.047687942000000004,0.009490216999999999,0.004414662,0.018287872,-0.0255355,-0.021791517000000003,-0.035517374,-0.056541234,0.021109878999999998,-0.083925794,-0.009845002,0.006112328,-0.101488212,1.101056876,2.457562682,-3.9751101230000003,-3.8369747010000004,-5.006561501,-3.358556221,-4.497249985,-3.176208206,-4.505271115,-1.652045349,-7.8134636878967285,-8.313117980957031,-5.513097763061523,-7.634212017059326,-8.809066772460938 -1412,1412,N98H,0.015152871000000002,-0.02890307,0.006697071,0.005904942,-0.049312425,-0.015938832,0.0010662269999999999,0.029239515,-0.16549719400000001,-0.014048253,-0.043757887,0.0021075670000000003,0.011286573999999999,-0.027808156,0.03961804,0.036741481,-0.13536633,1.1453971440000001,2.602042605,-0.965591313,-1.391428795,-2.121643555,0.161796745,-0.571994667,-0.904686295,-2.8280618110000004,-0.661646317,-5.764318466186523,-4.544271469116211,-4.278632640838623,-5.868329048156738,-5.892181396484375 -1413,1413,N98K,0.042041521,0.0007411439999999999,0.021190492000000002,-0.011860271,-0.033608341,-0.037479537,0.030731922000000002,0.053351119,0.079510447,0.003729933,-0.002247646,-0.005520766999999999,0.047901751,-0.027342407000000003,0.003621865,0.01930834,-0.086525022,1.2585913659999999,2.7027239410000004,0.202931544,0.841597626,-0.548608467,-0.198922386,-0.057519600000000004,0.97811055,-2.9278299760000004,1.025147372,-3.763289213180542,-3.1447105407714844,-2.5745463371276855,-4.402442932128906,-4.282620429992676 -1414,1414,N98M,-0.054674979000000005,-0.056781705999999994,-0.056999271,-0.09000504,-0.09343678300000001,-0.018537924,-0.079602267,-0.02974769,-0.14384365699999999,-0.042738438,-0.070824973,-0.056557352000000005,-0.05744119,-0.10173535199999999,-0.078274728,-0.014399035,-0.17247453,1.2739935759999998,2.399096019,-4.637998022,-4.119321793,-5.663316032000001,-4.723223419,-5.223176445,-3.460952423,-5.6068736789999996,-3.1489867960000004,-8.70230770111084,-7.843006610870361,-6.445465564727783,-8.757786750793457,-9.105707168579102 -1415,1415,N98L,-0.023855183999999998,-0.008639403,-0.015058771,-0.039489012000000004,-0.050658885,-0.041127783,-0.03009783,-0.017612538,-0.166472721,0.02757634,-0.044855146,0.017809244,-0.047926785,-0.035112381,-0.043865642,0.032481803999999996,-0.133799573,1.274576722,2.778318422,-4.20884799,-4.204166809,-5.330834785,-3.7892817919999997,-4.348469147,-3.3714874189999997,-5.568494152,-2.118202807,-7.3188066482543945,-5.924112796783447,-5.632002830505371,-7.7750773429870605,-8.55663013458252 -1416,1416,N98Q,-0.010719589,-0.027341094,-0.038164171000000004,-0.06074866599999999,-0.053535029000000005,0.06641855599999999,-0.013954268999999998,-0.0074849090000000005,-0.217885264,-0.016053618999999998,-0.038628569,-0.019971824,-0.056356517,-0.061540722,-0.059956609,0.008382872,-0.11545292900000001,1.1837811109999998,2.542245079,0.330404889,0.297806,0.051135941,1.1664465640000001,-0.231368706,0.368004646,-1.565293439,0.22332183,-3.8264126777648926,-2.329500198364258,-2.607137680053711,-5.333718776702881,-5.0454301834106445 -1417,1417,N98P,-0.020158334,-0.008225111,-0.022395536,-0.033124086000000004,-0.082870102,0.009425456,-0.043321128,0.003004461,-0.21151461800000002,0.009947145,-0.026397366000000002,-0.015658365,-0.029132707,-0.046745179000000005,-0.019502993,-0.030364662,-0.135375541,1.198251735,2.327531613,-4.111570451,-3.862544655,-5.172904396,-3.8833809969999997,-4.3925396580000005,-3.246482552,-4.651656141,-0.670724134,-5.319445610046387,-7.330192565917969,-5.301218032836914,-8.929368019104004,-7.842103958129883 -1418,1418,N98S,-0.03598568,-0.009592535,-0.022248828,-0.035697131,-0.049634646,-0.025664537,-0.06433409799999999,-0.007637260999999999,-0.207357271,0.035978512000000004,-0.055163582,0.004371674,-0.04886933,-0.048063392,-0.02333087,0.013192259,-0.11246155099999999,1.187801133,2.5553452269999997,1.04628614,1.426737839,0.982935432,0.317331047,1.362898384,1.141528,-1.250379407,1.900475956,-3.4677696228027344,-3.6728923320770264,-1.8441672325134277,-4.768249988555908,-3.594440221786499 -1419,1419,N98R,0.0061322880000000005,-0.017207493,-0.015119108999999999,-0.029459791000000003,-0.043622887,-0.000939688,-0.012678571000000001,0.024943147000000002,-0.17411146,0.010778688,-0.045193674,-0.010840276000000001,-0.019397941999999998,-0.025212382000000002,-0.03370719999999999,0.023742546,-0.110988319,1.671448915,3.643209181,-0.069411771,0.1007183,-1.505371368,0.796562515,0.154301468,0.106730232,-2.9914607280000003,0.361342275,-5.237752914428711,-4.413870811462402,-3.4042139053344727,-5.760606288909912,-5.67407751083374 -1420,1420,N98T,-0.03565817,-0.018741746,-0.037001757,-0.02993934,-0.056332568,-0.025935202999999997,-0.064812016,-0.006504323,-0.143113137,-0.005281109,-0.032202383,-0.010884443,-0.06311907,-0.031530725,-0.028347955,0.008916281,-0.121581417,1.149938831,2.549274354,-0.554833173,-0.26993206,-0.944186981,-0.874656433,-0.193412384,-0.49197800399999997,-3.0152901589999996,0.436962965,-5.184176921844482,-4.558663845062256,-3.2275161743164062,-5.537452697753906,-5.333915710449219 -1421,1421,N98W,0.012140661,-0.019065927,-0.014553523,-0.057602724,-0.040330557999999996,-0.015758444,-0.02665635,0.050937672,-0.202930445,0.013150384,-0.051282238,0.004926683,-0.034033729,-0.035019837000000005,-0.08018561099999999,0.024306665,-0.10496778,1.107887337,2.59724708,-6.085929366,-5.9115820470000005,-6.731229904,-5.736607941,-6.599089142,-5.451137794,-7.91037194,-6.695511649,-10.034965515136719,-11.4464750289917,-8.831089973449707,-10.980978012084961,-10.560627937316895 -1422,1422,N98V,-0.041429824,-0.021845772000000003,-0.022500507000000003,-0.044302182999999995,-0.048610582,0.019313926999999998,-0.057592067000000004,-0.025267581,-0.119427311,0.022829976000000002,-0.066521519,-0.00022031,-0.044780704000000005,-0.047845519,-0.040758846,0.046457312,-0.143678476,1.172144321,2.639365773,-3.3079825869999997,-2.863842064,-4.365923308999999,-2.7014003910000004,-4.267217934,-2.341529236,-4.183675522,-1.098257545,-6.930459499359131,-7.473258972167969,-4.867390155792236,-6.687952518463135,-7.492388725280762 -1423,1423,N98Y,-0.05282454599999999,-0.040095601,-0.024513781000000002,-0.035463022000000004,-0.019943187,-0.161192221,-0.090916303,-0.014732788,-0.177696558,0.039404399,-0.119595601,0.0015032889999999999,-0.050530850999999995,0.005792898,-0.076718942,0.038047919,-0.077934292,1.097788313,2.717351358,-3.841918619,-3.6693262410000003,-5.249736496000001,-3.7440200580000003,-3.761120567,-2.785389732,-5.093320008,-1.479884786,-8.034384727478027,-9.0623140335083,-6.975661277770996,-8.746941566467285,-8.512331008911133 -1424,1424,D99A,0.05969738,-0.037313322,0.028030612000000003,-0.025900744,-0.161376064,-0.017801836,0.051124080999999995,0.068270679,-0.013005686,-0.048973609,-0.025653035,-0.010398523,0.066459747,-0.033222944,-0.018578544,-0.163451945,-0.15930018199999998,1.432700019,2.197139854,-4.23175918,-3.991547493,-5.450327667000001,-4.035530869,-2.46140387,-5.2199860000000005,-3.448876903,-2.8327201730000002,-6.986983299255371,-7.774980545043945,-5.972904205322266,-7.638182640075684,-7.66218900680542 -1425,1425,D99C,0.257449568,-0.000131394,0.047169645999999996,-0.576618337,-1.991657821,-0.078596162,0.077662647,0.437236489,-0.062960263,-0.055349153,0.055086366,-0.016990718000000002,0.11133000900000001,-0.306662657,-0.846574017,-1.8187992130000001,-2.164516429,1.466399851,1.3799508280000001,-9.41817417,-9.313141242999999,-11.42490857,-9.525401085,-7.391768341000001,-9.435651611,-7.893012146,-6.183850052,-11.203112602233887,-14.251594543457031,-11.301480293273926,-12.944519996643066,-14.102034568786621 -1426,1426,D99E,0.041193925,0.008852435,-0.006571978000000001,-0.018170338,-0.05227557099999999,0.030824424,0.046337925999999995,0.036049924,0.035493464,-0.04289147,0.060596339000000006,-0.053250486,0.04010653,-0.02691298,-0.009427696,-0.076077906,-0.028473235,1.314858748,2.331832241,-2.7088392239999997,-2.1953058619999997,-4.066515076,-2.671161079,-1.712688293,-2.89852581,-3.222577307,-1.812277586,-7.20335054397583,-8.26502799987793,-5.5699262619018555,-5.659532070159912,-5.5058417320251465 -1427,1427,D99G,0.01001503,-0.035958625,0.005166134,-0.03399626,-1.6564993719999999,0.002235904,0.00811231,0.011917748999999998,0.017117147,-0.089126563,0.017209313,-0.044526576,0.054858843,-0.022279685,-0.045712834,-1.620385305,-1.692613439,0.8420426540000001,1.323853187,-6.785933836,-6.803525802999999,-8.108190697000001,-6.213188087000001,-5.1906619339999995,-7.614102661,-5.6389083939999995,-3.759315928,-10.023136138916016,-11.45832633972168,-8.626376152038574,-9.446871757507324,-10.262964248657227 -1428,1428,D99F,-0.063742016,-0.05460808,0.023652182999999997,-0.062770108,-1.484216288,-0.001012625,-0.09551145,-0.031972582,-0.012489735,-0.112916511,0.003700352,-0.016287677,0.063592042,0.006021483,-0.131561699,-1.248010144,-1.720422432,0.7002605,1.336323267,-9.539319472999999,-9.643980988,-11.40240302,-9.35550396,-8.30620443,-8.988504974,-6.275229242000001,-3.825376879,-10.046306610107422,-10.724417686462402,-11.260733604431152,-11.515416145324707,-12.284996032714844 -1429,1429,D99I,0.003891849,-0.06921793400000001,0.010444287,-0.01354972,-0.877720052,-0.0009801410000000001,-0.011553548,0.019337246000000002,0.011402603,-0.113615015,-0.024820852999999997,-0.073055549,0.093944123,-0.064649238,0.037549799,-0.625868277,-1.1295718270000001,1.1850305209999998,1.576904831,-8.602468781,-9.823257355,-9.644177597,-8.661802681000001,-6.732118645,-8.150987625,-6.409475691,-4.349427034,-10.843019485473633,-10.905526161193848,-10.9068603515625,-10.243088722229004,-10.73453426361084 -1430,1430,D99H,0.039733338,0.014870525,0.02323663,-0.023458897000000003,-0.172785852,-0.023017147999999998,0.038609508,0.040857167,0.10315563400000001,-0.01424002,0.043981069000000005,0.024666485,0.021806773999999998,0.035249584,-0.082167378,-0.145605622,-0.199966082,1.443704994,2.3238305880000003,-6.360419237,-7.263210526,-7.8996945720000005,-5.833371689,-5.188454002,-5.617365395,-6.446489923,-3.244715812,-7.997494220733643,-7.66703987121582,-6.067026138305664,-7.616427421569824,-9.77202033996582 -1431,1431,D99K,-0.011158986999999999,-0.036058634,0.004606321,-0.086114675,-0.7008136629999999,0.019587476,-0.006958789,-0.015359185,-0.041138733,-0.094567408,0.02245014,-0.056562865,0.065775507,-0.018610797,-0.153618552,-0.475721626,-0.9259056990000001,1.5298437740000002,1.87293527,-5.356528409,-5.915688927000001,-7.659986694,-3.5010073389999996,-4.994934509,-4.711024574,-5.216543729,-3.91408782,-8.553629875183105,-6.570291519165039,-8.11141586303711,-9.0810546875,-7.4933671951293945 -1432,1432,D99M,0.014362814,0.008897899,0.006360406,-0.052730501,-0.144838937,0.010476713,0.013809325,0.014916302,-0.008809655,-0.01980212,0.037597917,0.04130732,-0.028586509,-0.036820072999999995,-0.068640928,-0.141419477,-0.148258396,1.4852625419999999,2.319238645,-6.073796165,-7.721005402,-6.348201744,-5.896726723,-4.321337326,-6.081709632999999,-5.580931946000001,-3.434262598,-9.471202850341797,-6.628505706787109,-9.871977806091309,-9.737520217895508,-10.143067359924316 -1433,1433,D99L,0.06381155,0.001013681,0.019424333999999998,-0.011030367,-0.589505055,0.011371613999999999,0.046747624,0.080875476,0.046902817,-0.034518732999999996,0.036546095,0.010497693,0.028350973999999998,-0.0013759129999999999,-0.020684821000000003,-0.489155204,-0.689854906,1.048477467,1.579124131,-7.6815260379999994,-8.680904831,-9.351670448,-7.904357612999999,-5.532943596,-6.9377537,-5.940654443,-2.8447145860000003,-7.750792026519775,-9.273666381835938,-10.020782470703125,-10.076420783996582,-10.22056770324707 -1434,1434,D99N,0.061149347,-0.024148244,-0.04954016,-0.028789322000000003,-0.257325475,-0.059113535,0.09005025400000001,0.032248439,-0.021952113,-0.091642215,0.043345727,-0.10350577300000001,0.004425453,-0.011299165,-0.046279479000000005,-0.252494705,-0.262156244,1.438567451,2.059079851,-4.547261252,-5.3857472920000005,-4.949283432,-3.660800117,-4.285036667,-4.455438751,-4.514223828,-3.030382515,-7.709659099578857,-5.965056419372559,-7.15488862991333,-7.667608261108398,-6.879307270050049 -1435,1435,D99Q,0.10186898400000001,0.064430179,0.068215427,-0.012286406000000001,-0.07651013799999999,-0.062970579,0.064791282,0.138946685,0.024431732,-0.037210507000000004,0.166070864,0.020901576,0.11552927699999999,-0.027663224,0.0030904129999999998,-0.168713363,0.015693088,1.5575439359999999,2.327750822,-3.672040074,-3.91761692,-5.356920395,-3.4300271380000003,-2.533621414,-3.122014503,-3.5693769989999997,-2.8851756689999997,-7.225760459899902,-6.727550983428955,-6.637866973876953,-7.252814292907715,-7.502121925354004 -1436,1436,D99P,0.017780245,-0.000674694,0.031433897,-0.6336250520000001,-2.0321325630000002,-0.036428736,0.016774155,0.018786334,0.046075572999999995,-0.031597331,0.030247944,-0.005945605,0.068813398,-0.365062465,-0.9021876390000001,-1.935153436,-2.12911169,1.4517153230000002,1.351869571,-7.607034999,-7.87255098,-8.353636406,-7.909751076,-5.607567665,-8.291668869,-5.796579245,-4.703422496,-11.054933547973633,-11.6923246383667,-11.412238121032715,-12.869693756103516,-12.70569896697998 -1437,1437,D99S,0.059156312999999995,-0.023519996,0.021995325,-0.021117292000000003,-0.17350284800000002,-0.003275804,0.07863732799999999,0.039675298,0.02274548,-0.052976454000000006,0.005936461999999999,0.01438311,0.02960754,-0.016245831000000002,-0.025988753,-0.20466970199999998,-0.142335993,1.470013363,2.1658987880000002,-5.242174524,-5.591190117000001,-5.9060521470000005,-4.729450645,-4.042972618,-5.941207092000001,-4.939122278,-2.58330614,-7.906346321105957,-9.102992057800293,-6.799184322357178,-8.005016326904297,-9.008064270019531 -1438,1438,D99R,0.043124347,-0.009609758000000001,0.02024732,-0.03447462,-1.245599476,-0.005196682,0.057492750999999995,0.028755943,-0.009789434,-0.035857995,0.016638478999999998,-0.012359901999999999,0.052854542000000004,-0.02679829,-0.04215095,-0.9817136890000001,-1.5094852630000002,0.7377620570000001,1.362212404,-6.1358917470000005,-6.72232869,-8.116874603,-5.306523651,-5.002279045,-5.531452744,-6.438932212,-3.05567356,-9.153051376342773,-8.91385269165039,-8.717823028564453,-10.073552131652832,-10.288919448852539 -1439,1439,D99T,0.045820717000000004,-0.055323664,-0.02861519,-0.045525677,-0.40917352799999995,-0.0175048,0.038851379,0.052790054,0.046331001,-0.081428322,-0.029219006000000002,-0.070046259,0.012815878999999999,-0.058927424000000006,-0.03212393,-0.40616429200000004,-0.41218276299999995,1.531851368,1.9455833809999998,-5.938374051,-6.495173615,-6.75727317,-5.660947441,-4.425627396,-6.352848633,-5.046618357,-3.815897498,-9.177260398864746,-8.487367630004883,-7.885740280151367,-8.835067749023438,-9.38999080657959 -1440,1440,D99W,-0.114648221,-0.089662891,-0.02026665,-0.02426897,-1.876323526,-0.007905995,-0.127657118,-0.101639324,-0.027246125,-0.018138471,-0.161187311,0.056028294000000006,-0.096561594,0.048703465,-0.097241405,-1.676541614,-2.076105437,0.571382956,1.305859542,-9.552569899,-9.90162693,-11.29582437,-10.33617104,-8.245996932999999,-7.983230225,-7.82718039,-6.161939181,-11.00815486907959,-14.312857627868652,-11.79500961303711,-13.443123817443848,-13.347943305969238 -1441,1441,D99V,-0.022621959,-0.05738663,-0.021134105,-0.084733599,-0.354782275,-0.0038462229999999997,-0.044100115,-0.001143802,0.07382820799999999,-0.080700142,-0.034073118,-0.039758952,-0.002509258,-0.07218538099999999,-0.097281816,-0.32500759100000004,-0.384556959,1.677386192,2.145671348,-6.270678417999999,-6.979615578,-7.103794594,-6.219352524,-4.772352646,-6.278276749,-4.412421203,-2.9135714060000004,-9.725997924804688,-9.744950294494629,-9.297330856323242,-9.884281158447266,-9.593457221984863 -1442,1442,D99Y,0.053183579,-0.037141997,0.029745116000000002,-0.04101803,-1.513458825,0.004249629,0.038617923,0.067749235,0.018550188999999998,-0.039151341,-0.035132653,-0.00550998,0.065000212,-0.019142858000000002,-0.062893202,-1.20753825,-1.819379399,1.150632577,1.40953176,-9.734357687000001,-10.37588291,-12.87520291,-9.240058311,-8.097327408,-8.083316895,-5.958837476,-3.63623415,-8.960485458374023,-10.398656845092773,-9.886123657226562,-10.541285514831543,-11.388505935668945 -1443,1443,L100A,0.008624509,-0.0121834,-0.00035680099999999996,-0.670952843,-1.8748399009999999,0.023214347000000003,0.054282935,-0.037033917,0.007229405,0.034483876000000004,-0.058850676,0.001791359,-0.002504961,-0.350772929,-0.991132756,-1.884707541,-1.86497226,1.4563281190000001,1.365293004,-10.33374989,-9.4850065,-11.48482115,-11.64229968,-9.321733658,-9.734888474,-7.605768038,-2.951748358,-12.04259967803955,-14.237700462341309,-11.100830078125,-10.648849487304688,-11.59996509552002 -1444,1444,L100C,-0.006494503,0.0037854409999999996,-0.00299144,-0.131921006,-1.5784488190000001,0.015544671999999999,0.031295164,-0.044284169000000005,-0.003974119,0.059990518,-0.052419637000000005,-0.028802962,0.022820082000000002,-0.068445598,-0.195396414,-1.6180307859999998,-1.5388668509999999,0.934034445,1.330489842,-12.82224128,-11.61815456,-14.45777967,-15.16076732,-12.28250729,-10.59199757,-8.759084584,-3.703297913,-12.693685531616211,-15.494693756103516,-11.218265533447266,-12.783927917480469,-14.731073379516602 -1445,1445,L100E,0.069085177,0.026311212,0.063420013,-1.264837643,-2.299156545,0.020310343,0.114810433,0.02335992,0.009706429,0.052536723,8.57e-05,0.051831058,0.075008967,-1.054939917,-1.4747353680000002,-2.41709392,-2.18121917,0.66682379,0.7384636440000001,-13.46424802,-11.23469312,-15.10226397,-14.99543226,-14.53352421,-11.45532656,-7.9765839110000005,-4.681008609,-15.590785026550293,-15.190468788146973,-12.772806167602539,-13.002098083496094,-13.872215270996094 -1446,1446,L100D,-0.0009916360000000002,-0.057543735,-0.949085307,-2.4023945319999997,-2.838073156,0.04314573,0.05091213,-0.052895400999999995,-0.044562732,-0.032957888,-0.082129582,-0.765119311,-1.133051303,-1.859991063,-2.944798001,-2.5689325519999997,-3.107213759,2.2477273380000002,1.0361176109999999,-13.62008586,-12.22181487,-15.38080258,-15.471788199999999,-12.35701683,-12.66900681,-9.256658105,-5.710736052000001,-16.921005249023438,-16.484073638916016,-15.663749694824219,-14.45630931854248,-15.421557426452637 -1447,1447,L100G,0.04452576,-0.012661908000000001,-0.056458048,-1.482686804,-2.556103373,0.010820773999999998,0.069046912,0.020004608,0.017126442,0.0059398359999999996,-0.031263652,-0.033696927,-0.07921916799999999,-1.3727541380000001,-1.592619469,-2.257786886,-2.8544198589999996,0.829764528,0.7267228029999999,-14.38790148,-13.10093684,-15.54106105,-16.82932954,-13.88644078,-12.58173921,-8.463441861,-4.4412701,-15.392030715942383,-17.05864906311035,-14.576421737670898,-14.273591041564941,-15.48366928100586 -1448,1448,L100F,0.012780472,-0.099574358,-0.081196897,0.017743609,-0.800498928,0.077016204,0.023983859,0.001577085,-0.067379677,-0.107300274,-0.091848441,-0.130620939,-0.031772855,-0.014714405,0.050201623,-0.640290085,-0.9607077709999999,1.089826752,1.526499346,-8.781433965,-8.611037048,-8.736151833,-10.0788875,-7.166269592000001,-9.314823845,-6.5728883279999994,-2.7411285810000003,-11.017529487609863,-11.021376609802246,-9.551098823547363,-8.094731330871582,-9.8974609375 -1449,1449,L100I,-0.0074133440000000005,-0.025425415,-0.065945604,0.04125572,-0.058038304000000006,-0.046753502,-0.016918523,0.002091835,-0.003705924,0.02447019,-0.07532102,-0.01078439,-0.121106818,0.07618744599999999,0.006323994,-0.017825125,-0.098251483,1.2984642990000002,2.633524663,-3.796006682,-3.470388252,-3.276826218,-4.63614193,-4.205289978,-3.391387032,-3.950540725,-0.9844488779999999,-7.3344268798828125,-8.077105522155762,-8.458608627319336,-5.892124176025391,-6.072082996368408 -1450,1450,L100H,0.12096192800000001,0.001193637,0.015603395,-0.596797806,-2.30765856,-0.038398616,0.13256462300000002,0.10935923199999999,0.040551502999999996,-0.017906398,0.020293671,-0.029786164,0.060992954,-0.46216611399999996,-0.731429497,-1.748344011,-2.8669731080000003,1.770083663,1.469609763,-15.25721549,-12.58586889,-16.86267957,-19.41557101,-13.68262695,-13.73933102,-8.320346232999999,-4.428723057,-14.185308456420898,-13.862943649291992,-11.35256576538086,-10.405624389648438,-14.758234024047852 -1451,1451,L100K,0.015045035,0.050939232,-0.032120966,-0.59514723,-2.008377529,0.058340918,0.02151788,0.00857219,-0.06716715200000001,0.085794008,0.016084456,0.052602589000000005,-0.11684452,-0.259753107,-0.930541353,-1.7645746130000002,-2.252180445,1.232671325,1.3503532630000001,-13.84331668,-11.27451962,-17.19906342,-16.03039008,-13.06815162,-11.64445865,-8.181461087,-1.5603659730000001,-13.545568466186523,-12.199274063110352,-9.356382369995117,-9.970412254333496,-12.801093101501465 -1452,1452,L100M,0.08106224599999999,0.003399156,0.035572192999999995,0.059511075999999996,-0.046431063,-0.082988235,0.08828796800000001,0.073836523,-0.07418519900000001,0.041089242000000005,-0.03429093,0.076825435,-0.0056810490000000005,0.06555902,0.053463132000000003,0.004581709000000001,-0.09744383400000001,1.1807842659999999,2.76503108,-5.612350417999999,-4.590950951,-6.8354943079999995,-5.636746521,-5.614126923,-5.384433388,-5.93507021,-2.229269104,-9.169737815856934,-9.095638275146484,-7.21733283996582,-7.5175652503967285,-7.612893104553223 -1453,1453,L100N,-0.03520194,-0.040607702999999995,0.002554084,-1.538654494,-2.6504243769999998,-0.005670916,0.0033220359999999996,-0.073725915,-0.025327572000000003,0.032771941,-0.11398734599999999,0.03543657,-0.030328402,-1.227408551,-1.8499004369999998,-2.209351312,-3.0914974410000005,0.6059375579999999,0.7206050820000001,-13.98995523,-12.59193236,-16.51840735,-16.67777971,-12.98877168,-11.17288505,-8.905826304,-5.556639337000001,-14.888299942016602,-14.839601516723633,-13.74928092956543,-12.125824928283691,-14.570274353027344 -1454,1454,L100Q,-0.00752974,-0.031418546,-0.004820762,-0.07634366,-2.118330946,0.068156648,0.053867820999999996,-0.068927301,-0.11135604800000001,0.054957485,-0.117794576,0.0632825,-0.072924023,-0.0077566430000000006,-0.144930676,-1.563203935,-2.6734579569999997,0.49850068299999994,1.308308003,-13.31099151,-11.64330601,-15.79271571,-15.42940668,-12.17757915,-11.51195002,-8.012480047999999,-3.460561815,-12.263009071350098,-11.89854621887207,-10.29352855682373,-8.78582763671875,-12.912651062011719 -1455,1455,L100P,0.009922851,-0.017830736,-0.48469101700000006,-1.666375229,-2.5742951880000002,0.023910362999999997,0.034491897,-0.014646196,-0.071032917,0.004670035,-0.040331506,-0.345200935,-0.624181099,-1.459967515,-1.872782942,-2.674058983,-2.474531393,1.576946984,0.86369468,-12.56784305,-11.57957814,-13.75393157,-14.41034171,-11.84157236,-11.25379146,-7.822430705,-3.874440405,-13.023614883422852,-12.498720169067383,-13.027058601379395,-12.615936279296875,-12.408034324645996 -1456,1456,L100S,-0.016146079,-0.043350732,-0.002183637,-0.963785208,-1.9799980240000001,0.03002095,0.005519099,-0.037811257,-0.069093055,0.06019559,-0.146897053,0.016538736999999998,-0.020906011000000002,-0.706139745,-1.221430671,-1.7645746130000002,-2.195421434,2.078888191,1.594958114,-11.97116391,-11.60446395,-13.41348696,-15.28490882,-10.10823294,-9.444726897999999,-8.289123435,-4.067252454,-13.101241111755371,-14.43901252746582,-11.684025764465332,-11.613170623779297,-13.151461601257324 -1457,1457,L100R,0.035183038,0.028796212999999998,0.019032855,-0.900364816,-2.178643147,0.053522692999999996,0.072583005,-0.002216929,0.039455132999999996,0.04414355,0.013448876,0.01306036,0.02500535,-0.5960143689999999,-1.2047152620000001,-1.9238293480000002,-2.433456945,1.805450711,1.4326109669999998,-12.88631851,-10.7898325,-14.51293217,-15.33464972,-11.97701739,-11.81716077,-7.393167383,-1.323566,-11.950267791748047,-10.870797157287598,-7.818476676940918,-9.265880584716797,-13.22024917602539 -1458,1458,L100T,0.01287456,-0.019500061000000003,-0.008604126,0.041854564,-1.8213999280000002,0.016153498999999998,0.027241134,-0.001492015,-0.058064477,0.016325445,-0.055325566,-0.021339982,0.004131731,0.024002412999999997,0.059706714,-1.74340976,-1.8993900959999999,0.653236191,1.306784194,-10.24344375,-9.864686562000001,-11.38535329,-11.49342517,-9.973880402,-8.499873314,-7.163056435,-3.654258309,-12.89405632019043,-13.231874465942383,-10.053693771362305,-10.962207794189453,-11.276034355163574 -1459,1459,L100W,0.039834702,0.193503736,0.023915758999999998,-0.19969722199999998,-1.185561117,-0.075500213,0.077120497,0.002548907,-0.143834194,0.08996994900000001,0.297037522,-0.022402717000000003,0.070234235,-0.125243398,-0.274151045,-0.885337409,-1.485784825,1.5072491559999999,1.636807226,-12.96410663,-11.10182265,-14.53266254,-15.01579838,-11.34495219,-12.82529742,-8.537392602999999,-4.372547541,-13.843002319335938,-14.3946533203125,-9.894082069396973,-11.80453109741211,-14.367477416992188 -1460,1460,L100V,0.022807697000000002,-0.025810865,-0.031260768,-0.0016410510000000001,-0.055273939,-0.009363071,0.0052598390000000005,0.040355554,0.018198766,-0.003786767,-0.047834962,-0.032706402999999995,-0.029815132,0.022679814,-0.025961916,-0.025233372,-0.085314506,1.296077307,2.60688446,-5.027358707,-4.456010727,-4.798056648,-5.245660141,-5.714666939,-4.922399078,-4.534087918,-1.351412077,-7.926444053649902,-9.416467666625977,-9.743036270141602,-7.513598442077637,-5.859579086303711 -1461,1461,L100Y,0.02130023,-0.044975232999999996,-0.04621499900000001,-0.158632519,-1.5215590490000002,-0.002148319,0.048840149000000006,-0.00623969,0.023011649,-0.03769053,-0.05225993599999999,-0.011717817,-0.080712181,-0.046248145,-0.271016892,-1.557535694,-1.485582404,0.746966791,1.321193804,-12.60114666,-10.51082557,-13.405447800000001,-14.79172868,-11.09430486,-13.20342639,-8.069938448,-2.732712442,-13.125557899475098,-14.839095115661621,-11.508821487426758,-9.952292442321777,-12.96302318572998 -1462,1462,V101A,0.008206899,-0.074177884,-0.025509105,0.00012377700000000002,-0.700294787,-0.114270741,-0.01549127,0.031905067,-0.026152135,-0.047745897,-0.10060987,-0.004642138,-0.046376072000000004,0.006913988,-0.006666435,-0.523805793,-0.87678378,1.344793343,1.732996815,-3.880361235,-4.000896461,-3.7778118519999997,-4.13847258,-3.681284386,-3.803340897,-4.2499772160000004,-1.977798999,-8.943855285644531,-10.281689643859863,-8.348100662231445,-7.284741401672363,-9.777571678161621 -1463,1463,V101C,0.00140295,-0.054240445,-0.029033315,-0.03815164,-0.5956654929999999,0.045219282,0.003997926,-0.0011920260000000001,-0.030713266,-0.009221036,-0.09925985300000001,0.02776253,-0.085829159,-0.012394608,-0.063908672,-0.432543664,-0.7587873209999999,0.9766890770000001,1.573872006,-8.208125743,-7.445195602,-8.641171906,-9.20864167,-7.824709831,-7.920909706000001,-5.676097181,-4.648518448,-11.52556037902832,-13.689992904663086,-10.119314193725586,-12.157873153686523,-12.974791526794434 -1464,1464,V101E,0.01716608,-0.02887265,0.00331768,0.013008437,-0.7439831159999999,-0.067678153,-0.006063003000000001,0.040395163,-0.046835444000000004,-0.019456258,-0.038289041,0.058245795,-0.051610435999999996,0.05431867,-0.028301797000000004,-0.695010265,-0.792955966,0.587891272,1.375472555,-3.985370969,-3.069192596,-4.284347839,-5.517246414,-2.866098198,-4.189969795,-3.9353534160000003,-2.854220241,-11.220137596130371,-13.894105911254883,-9.375853538513184,-8.130870819091797,-11.75692367553711 -1465,1465,V101D,-0.085234134,-0.036065667,-0.065456291,-0.015518456000000002,-0.211748794,-0.10410034900000001,-0.09526550199999999,-0.07520276599999999,0.060365817999999995,0.005628085,-0.07775941900000001,0.014042131999999999,-0.144954713,-0.02389062,-0.007146291,-0.18608726899999997,-0.23741031899999998,1.426412995,2.138902501,-4.014523843,-2.998678535,-3.525042107,-5.957768463,-2.969657921,-4.6214721910000005,-2.768067491,-3.160112619,-12.091930389404297,-14.321708679199219,-11.120875358581543,-10.51947021484375,-13.188081741333008 -1466,1466,V101G,-0.082446243,-0.123052652,-0.103543162,-0.058004734,-1.239269328,-0.038792621,-0.069823237,-0.09506924900000001,-0.048811615999999995,-0.14211743699999999,-0.103987866,-0.051330932999999995,-0.155755391,-0.051400975,-0.064608493,-1.091866486,-1.38667217,0.97351283,1.3887435259999998,-6.41122159,-6.194864738,-7.382337112,-6.356102562,-6.884453872999999,-5.238349663,-3.921357758,-3.41415185,-10.811275482177734,-14.278284072875977,-11.06751823425293,-11.008340835571289,-12.96854305267334 -1467,1467,V101F,-0.051049702,-0.08482070900000001,-0.068893434,-0.015050727,-1.869255391,0.009158333000000001,-0.049471927,-0.052627476,0.021181024,-0.086754618,-0.082886799,-0.045692248,-0.09209462,-0.027755664,-0.002345789,-1.627509609,-2.111001173,0.8123136990000001,1.32068704,-9.260007652,-7.865620659,-10.16602711,-9.879875145,-9.158323142999999,-9.2301922,-6.1432449270000005,-5.495342057,-10.60818862915039,-12.816633224487305,-10.101784706115723,-10.926531791687012,-11.817688941955566 -1468,1468,V101I,-0.0036803170000000002,-0.032331708,-0.045749995,-0.016762254,-0.10114804599999999,-0.081834226,-0.020841701,0.013481067,0.009234178000000001,0.014061253000000001,-0.078724669,0.026961249,-0.11846123800000001,0.014299131000000001,-0.047823637999999995,-0.061324348,-0.140971743,1.186960563,2.419344848,-2.131982387,-1.497711227,-2.015309097,-3.255734673,-2.22829332,-1.662863617,-1.404562806,-2.256641381,-6.295075416564941,-7.934385299682617,-5.839520454406738,-5.863600254058838,-6.24576473236084 -1469,1469,V101H,-0.142654277,-0.070281178,-0.160339964,-0.140443256,-1.336747924,-0.037576436,-0.062560803,-0.22274775100000002,-0.032849754,-0.072748166,-0.06781419,-0.088290221,-0.232389707,-0.075882964,-0.205003548,-1.068414445,-1.605081403,1.012516162,1.399890844,-7.833984833,-6.200201767,-8.863086891,-9.964238686,-5.4473797379999995,-8.695017082,-5.508236307000001,-3.5381382360000004,-11.78636646270752,-14.239378929138184,-11.163785934448242,-11.058365821838379,-13.87855339050293 -1470,1470,V101K,-0.045799587,-0.050880935,-0.061683167000000004,-0.026262723999999998,-0.277032486,-0.08770524099999999,-0.081031083,-0.01056809,0.03527576,-0.027970472000000003,-0.073791398,0.037573103,-0.160939436,0.008216954,-0.060742400999999994,-0.22802276300000002,-0.32604220899999997,1.04235952,1.808523932,-5.812260892,-3.5936513210000003,-6.24624646,-7.171289268,-5.389449333,-6.660668076,-4.274398338999999,-3.2189137619999997,-8.77294921875,-11.655159950256348,-8.868608474731445,-7.311305046081543,-11.409322738647461 -1471,1471,V101M,-0.048310375,-0.014179108000000001,-0.004076687,-0.005777791,-0.242102515,0.000534606,-0.106007802,0.009387052,0.028969499,-0.013066696000000001,-0.015291518999999998,0.0645793,-0.072732674,0.044297641,-0.055853223,-0.223513767,-0.260691263,1.435380181,2.134776638,-4.416560565,-3.2825156630000003,-5.143993752,-4.74832563,-4.505488739,-4.4024790419999995,-3.2910483680000002,-3.3427210780000003,-7.950689792633057,-9.79616928100586,-8.766319274902344,-7.528187274932861,-8.414676666259766 -1472,1472,V101L,0.007674565,-0.062413453,-0.030946065,-0.028630777000000003,-0.08078445599999999,0.15811939,-0.019943159,0.035292289,-0.01748611,-0.073043126,-0.051783779,-0.015315171,-0.046576957999999995,-0.038212658999999996,-0.019048895,-0.119567417,-0.042001495,1.4275645730000002,2.3730432269999997,-2.0949223619999997,-0.936562508,-2.969531052,-2.891577209,-1.8813328630000001,-1.7956081769999999,-2.4194213369999997,-1.12586454,-4.559598922729492,-9.31853199005127,-5.748970031738281,-6.236097812652588,-5.79541015625 -1473,1473,V101N,-0.059574302999999995,-0.053307408,-0.053331051,-0.033133682000000005,-0.804123866,-0.00892416,-0.025155449,-0.093993157,0.013061946999999999,-0.023901831000000002,-0.082712985,0.023916871,-0.130578972,-0.023364056,-0.042903308,-0.688761315,-0.919486417,0.8828937790000001,1.451681311,-6.851215872,-4.87930722,-7.0299604339999995,-8.799150688,-5.910724159,-7.6369368589999995,-5.325274756000001,-3.80443933,-10.960351943969727,-13.782719612121582,-11.119359970092773,-10.6308012008667,-12.50124454498291 -1474,1474,V101Q,0.028234629,-0.074500394,-0.064478207,-0.122584557,-0.253280102,-0.05782595,-0.0035157590000000002,0.059985015999999995,-0.048126068,-0.04617759900000001,-0.10282318900000001,-0.040191057999999995,-0.088765355,-0.112234703,-0.132934411,-0.21631756,-0.290242644,1.603270779,2.222565483,-3.8043398969999997,-2.68290757,-4.656007332,-4.925435654,-2.599790192,-4.157558739,-3.383533512,-2.830214008,-10.25137710571289,-12.97754955291748,-9.018744468688965,-7.743027687072754,-11.770751953125 -1475,1475,V101P,-0.044586013,-0.061496819,-0.903788175,-1.891763742,-2.538546594,-0.046694285999999995,-0.040663833999999996,-0.048508192,-0.004657149,-0.051278539000000005,-0.071715098,-0.695284123,-1.1122922259999999,-1.7306690619999998,-2.052858422,-2.577126011,-2.499967177,2.231668402,1.088860772,-6.572604436000001,-5.912687087999999,-7.925654701,-8.041247398,-5.494071762000001,-5.489361229,-4.8391280210000005,-4.393586076,-9.571115493774414,-12.32856559753418,-10.44129753112793,-11.09557819366455,-11.682836532592773 -1476,1476,V101S,0.025896471,-0.047804625,-0.047244324000000004,0.002169952,-0.734571924,-0.12468245300000001,-0.018641537,0.07043447900000001,0.043303815999999995,-0.04302991900000001,-0.05257933099999999,-0.031036242000000002,-0.063452406,-0.034332088999999996,0.038671992,-0.690441106,-0.7787027409999999,1.0175741409999999,1.482115366,-5.707502646,-5.347594399,-5.169382431,-5.959848465,-6.1121203,-5.948567635,-4.457939644,-2.300164485,-10.226116180419922,-13.058696746826172,-9.656278610229492,-10.120223999023438,-12.254446029663086 -1477,1477,V101R,-0.029726575,-0.071618527,-0.06318036099999999,-0.047036554,-0.498956704,-0.097602212,-0.056275436,-0.0031777140000000003,0.002532095,-0.072453217,-0.070783837,-0.026240007000000003,-0.100120714,-0.054944090999999994,-0.039129016,-0.49515197899999996,-0.502761429,1.366071089,1.752833536,-5.432205493,-3.78891935,-6.812360054,-5.793337417999999,-3.743504906,-7.022905739,-4.296788008,-2.98782462,-9.138936042785645,-11.613289833068848,-8.863059043884277,-8.091530799865723,-12.247735023498535 -1478,1478,V101T,0.019684723,-0.012713367,-0.018160093999999998,0.007474944,-0.118362671,-0.110620274,-0.0020525929999999997,0.041422038,-0.018321086,0.01312904,-0.038555774,0.066667486,-0.102987674,0.0037529940000000004,0.011196893000000001,-0.12877002699999998,-0.107955315,1.2507182479999999,2.1352310919999997,-4.827128206,-4.22329908,-3.573408829,-5.426389747999999,-4.878798126,-6.033745247000001,-3.597625433,-1.59421207,-8.908495903015137,-10.678121566772461,-8.150729179382324,-8.41269302368164,-9.159862518310547 -1479,1479,V101W,-0.118609412,-0.085934709,-0.129582387,-0.27201754100000003,-2.291497139,0.13253715300000002,-0.17724783600000002,-0.059970987,0.10115811300000001,-0.07355316099999999,-0.09831625599999999,-0.076364138,-0.18280063600000002,-0.15946779,-0.38456729100000003,-1.996969896,-2.5860243819999997,1.176680558,1.321391186,-9.296819786,-7.964083351,-9.725465446,-9.787296547,-8.687521454,-10.31973213,-6.320729172999999,-5.48555408,-12.492152214050293,-15.820698738098145,-12.3570556640625,-14.413349151611328,-13.985211372375488 -1480,1480,V101Y,-0.023634122,-0.052784914,-0.021404766000000002,0.002228609,-1.5029203580000001,-0.023810401000000002,-0.051837695999999996,0.004569452,-0.028127705,-0.031355481,-0.074214346,-0.015984963999999997,-0.026824567,-0.011095421999999999,0.01555264,-1.7713858740000001,-1.234454842,0.653236191,1.306784194,-9.572959401,-8.212651512,-11.42275547,-10.31059773,-7.713855865,-10.20493642,-6.376426021,-2.666014004,-11.736144065856934,-14.494665145874023,-11.232254028320312,-12.431293487548828,-13.524280548095703 -1481,1481,E102A,0.009324818,-0.011267963,-0.040806359,-0.001681521,0.016406132,0.093191201,0.017112309,0.0015373270000000002,-0.057500062000000005,0.015545413000000001,-0.038081339,0.007226318000000001,-0.088839036,-0.009789404,0.006426362,0.088845584,-0.05603332,1.139982465,2.831820233,-1.343915956,-1.8154311980000002,-1.3435783000000001,-1.120621513,-1.862148422,-0.577800346,-2.498388331,0.12264348,-3.74861741065979,-5.566641807556152,-3.022367000579834,-3.755436420440674,-4.33221435546875 -1482,1482,E102C,0.03817808,0.020783745,-0.009173915999999999,-0.294042918,-1.752428509,0.075337212,0.026616461,0.049739698,-0.06698461900000001,-0.043643462,0.08521095199999999,-0.046044697999999995,0.027696866,-0.217896912,-0.370188924,-1.515160298,-1.9896967190000001,1.341388528,1.405567536,-8.232932544,-8.797414162,-8.187144607999999,-7.543496971000001,-9.597824142,-7.038782837,-8.841266829,-7.868517891000001,-8.238555908203125,-9.764103889465332,-7.253316402435303,-11.457412719726562,-7.737964630126953 -1483,1483,E102D,0.084501334,-0.037281977,-0.01120785,0.0032559959999999997,-0.0029742379999999997,-0.055364285,0.053865706,0.115136962,-0.073139913,-0.099188284,0.02462433,-0.037955762000000004,0.015540062,-0.039662496,0.046174487,0.027913937000000003,-0.033862413,1.132670201,2.661337655,-0.674036978,-0.819597687,-0.674686943,-0.331117676,-1.7168140490000001,0.172031464,-2.208766519,0.354471828,-3.5358641147613525,-5.9594035148620605,-3.890105724334717,-4.84852933883667,-2.9874651432037354 -1484,1484,E102G,0.040304391,-0.020944637,-0.044042417,-0.007946243,-0.29465882,-0.090591265,0.031969668,0.048639113,-0.04062282,-0.042781599000000003,0.000892325,-0.025419334,-0.062665499,-0.034307755,0.01841527,-0.21390542699999998,-0.375412213,1.320039096,2.004616634,-4.315171599,-4.054072456,-3.9234917680000003,-3.124240349,-7.553096039,-2.920957382,-3.8058492289999997,0.6926375020000001,-2.027733325958252,-5.579219818115234,-4.313270568847656,-3.9448699951171875,-3.76448130607605 -1485,1485,E102F,0.047593372,-0.031544983,-0.024743712,-0.00882471,-0.08769159900000001,0.118680762,0.011223055,0.08396368800000001,0.063358804,-0.123857767,0.060767802,-0.076738442,0.027251018,-0.03673505,0.01908563,-0.07633884,-0.09904435699999999,1.277959855,2.292871582,-7.0934793439999995,-10.14669139,-7.010332642000001,-5.680098984,-7.00747506,-5.622798645,-5.300078281,-2.251818605,-5.552835941314697,-9.257955551147461,-6.474254608154297,-7.224468231201172,-7.896049499511719 -1486,1486,E102I,0.008491857,-0.04983913,0.023612084,-0.022212045,-0.09800573800000001,0.29117825399999997,0.0033915959999999998,0.013592116999999999,0.098993168,-0.097017765,-0.002660495,-0.00495163,0.052175797999999995,0.010456719,-0.054880807999999996,-0.049956985999999995,-0.14605449,1.232510956,2.4574268790000002,-6.386460905,-8.307892403,-4.518826889,-4.512192841,-8.962811745,-5.63058065,-5.655494227,-2.288066357,-6.282534599304199,-5.607086658477783,-4.180513381958008,-8.482526779174805,-6.0278778076171875 -1487,1487,E102H,0.01640576,-0.044646385999999996,-0.083456721,-0.095656738,-0.068771438,0.075979735,-0.010922683999999998,0.043734204000000006,0.155856864,-0.103943101,0.014650328999999998,-0.067147861,-0.09976558,-0.11478117300000001,-0.076532302,-0.018109408,-0.119433468,1.349850147,2.429634139,-5.48800166,-5.051740532,-5.630500641,-4.86459774,-7.052422622999999,-4.840746765,-5.093037183,-3.233006899,-4.117213249206543,-8.174182891845703,-5.412294387817383,-7.392543315887451,-5.324419021606445 -1488,1488,E102K,0.06217737,-0.013209647,0.051156691,0.02096043,-0.062874373,0.57346682,0.057277157999999995,0.067077582,-0.154563648,-0.031005948,0.004586655,-0.07353330200000001,0.175846683,-0.039458937,0.08137979599999999,-0.04779888,-0.077949865,1.5464736069999998,2.938183126,-2.890925082,-2.715477615,-3.0552623139999997,-3.095536133,-2.9459838260000004,-2.642365524,-2.753194389,-1.256679882,-3.7253048419952393,-6.925766468048096,-2.950925350189209,-5.658515930175781,-4.2108259201049805 -1489,1489,E102M,0.031540671,-0.04680941,-0.078978543,-0.013850513,-0.062337675999999995,0.36895036700000006,0.018357915,0.044723426,0.038115748,-0.068310857,-0.025307963,-0.067710183,-0.090246903,-0.023413062000000002,-0.004287964,-0.007049118,-0.11762623400000001,1.223079145,2.5155720169999998,-7.317632324,-8.891729172,-6.44075914,-6.26672892,-8.594620201,-6.394324188,-5.6845199939999995,-3.388936278,-5.92402982711792,-7.764457702636719,-5.636989116668701,-8.933160781860352,-6.952759742736816 -1490,1490,E102L,-0.006275741,-0.010432165,-0.057204765,-0.038738426,-0.06177225,0.18268347100000001,-0.034371565,0.021820082999999997,-0.038022214,-0.039957769,0.019093439,-0.03753098,-0.07687855,-0.034852693,-0.042624159,-0.009280985,-0.11426351400000001,1.209166103,2.536844099,-6.510111387999999,-7.429902374,-5.6967720029999995,-5.688899848999999,-8.347153587000001,-5.387829124,-5.64632106,-1.225266268,-5.249736785888672,-6.773433208465576,-4.819909572601318,-7.941448211669922,-6.095355033874512 -1491,1491,E102N,0.012213955,-0.045907116,-0.049959262000000004,0.006167113,-0.08630534699999999,0.069316667,-0.07063747299999999,0.095065383,0.296111112,-0.048221802,-0.043592429,-0.018143727,-0.081774797,0.000398714,0.011935511999999999,-0.015796712,-0.156813982,1.184187625,2.515322054,-3.3145106089999996,-3.437925491,-3.17030925,-2.581079033,-4.781284988,-2.601954285,-4.727050118,-1.206964237,-3.781846284866333,-5.848733901977539,-4.226646423339844,-5.1171979904174805,-2.6358518600463867 -1492,1492,E102Q,0.02061284,-0.004829368,-0.063993284,-0.020900025,-0.045655707999999996,0.145492132,-0.014632137,0.055857817000000004,-0.059044065,-0.022341431000000002,0.012682695,-0.056801164,-0.071185403,-0.06412864,0.02232859,0.029051498,-0.120362914,1.082345107,2.565519696,-4.386887163,-3.960969078,-4.304307701,-4.01247226,-5.473025573999999,-4.1836612010000005,-5.527484835,-2.043886294,-3.9105961322784424,-6.940199851989746,-4.136197566986084,-5.742506504058838,-5.536504745483398 -1493,1493,E102P,0.038249172000000005,-0.002460804,-0.022889627000000003,-0.019182979,0.007137683000000001,0.09211499599999999,0.012390265,0.064108078,-0.041275601,-0.04396840900000001,0.039046801,-0.044942734000000005,-0.000836519,-0.057885215,0.019519256999999998,0.032059817000000004,-0.017784452,1.2585913659999999,2.7027239410000004,-2.620635217,-2.9631420060000004,-2.3699873119999997,-2.9603210910000004,-3.099378342,-1.7103473359999999,-3.743732657,0.7482069440000001,-3.693469285964966,-6.577101230621338,-3.3493099212646484,-4.294149398803711,-4.23245906829834 -1494,1494,E102S,0.05995079,-0.005103225,-0.001061905,0.001762195,0.012132849,0.14538905800000002,0.032424102999999996,0.087477477,-0.035802712,-0.027116631000000002,0.016910182,-0.01189591,0.009772101,-0.035596431,0.039120821,0.041468617,-0.017202919,1.083897781,2.677064204,-1.308189906,-0.650446152,-1.637133102,-1.280035049,-2.60889576,-0.364439468,-2.712106753,0.021227588999999998,-2.768679141998291,-5.36395788192749,-2.1185193061828613,-3.5675065517425537,-2.735419273376465 -1495,1495,E102R,0.013658168,-0.003216132,-0.053470786,-0.048473594,-0.112260649,0.34711543200000006,-0.010739465,0.03805580000000001,-0.036089128,-0.041510326,0.035078062,-0.06530898,-0.041632591000000004,-0.07519330099999999,-0.021753886,-0.085959189,-0.13856210800000002,1.426699217,2.364769258,-4.314601163,-4.751068985,-3.52405098,-4.108197594,-6.120448586,-3.06923967,-5.290723528,-1.5088251719999999,-4.628424644470215,-7.4611077308654785,-3.655355453491211,-6.905191898345947,-5.3551530838012695 -1496,1496,E102T,0.018578095,-0.036185839,-0.050671618,-0.027174231,-0.019363092,0.101853035,-0.015841258,0.052997447,-0.003918902,-0.044475951,-0.027895727000000002,-0.029847345,-0.07149589099999999,-0.040464941000000004,-0.01388352,0.04698381,-0.085709994,1.272442665,2.77972392,-0.568495905,-1.162286949,-0.500584045,0.070184097,-1.269374565,0.01958194,-1.745315367,-0.099689136,-2.295159101486206,-2.3734259605407715,-1.787553310394287,-4.111244201660156,-0.9191875457763672 -1497,1497,E102W,0.039110305,-0.040687855,-0.07582353900000001,-0.0267243,-0.754648517,0.17349794300000002,0.009531412,0.06868919700000001,-0.058809470999999995,-0.09510489400000001,0.013729185,-0.059090141,-0.09255693599999999,-0.102768496,0.049319897,-0.607386987,-0.9019100459999999,1.08192449,1.5819141540000001,-8.513880128,-10.29420113,-8.831783478,-7.270202133,-9.254826851,-6.918387054,-6.9873228329999995,-4.608140957,-7.094783782958984,-10.91431999206543,-6.649249076843262,-11.087886810302734,-8.790340423583984 -1498,1498,E102V,0.004545399999999999,-0.002425635,-0.0346032,-0.028692036,-0.013551253999999999,0.152050241,-0.029428149,0.038518948,-0.037302743,-0.04292256,0.03807129,-0.025311912000000002,-0.043894487999999995,-0.046921207,-0.010462865,0.034172925,-0.061275432000000005,1.201001598,2.6734840859999998,-4.096636218,-5.643042847,-1.81495919,-2.92001326,-6.355567252999999,-3.749598541,-4.046628611,-1.160749028,-4.985713958740234,-6.559417247772217,-3.09245228767395,-6.910212516784668,-5.415859222412109 -1499,1499,E102Y,0.046666955999999996,0.026181052000000003,0.01925528,0.0632316,-0.043454595,0.11932593400000001,-0.007183131999999999,0.100517044,0.01897743,0.017599386,0.034762718,0.01061948,0.02789108,0.023395332,0.103067868,0.032808621,-0.119717811,1.1443711540000001,2.808825171,-6.80886499,-8.305018318,-6.945234612,-5.4005653229999995,-7.673615402,-5.719891296,-5.347930821,-2.396955138,-5.572780609130859,-8.888559341430664,-6.485194206237793,-8.654858589172363,-7.006122589111328 -1500,1500,Y103A,-0.03559329,-0.048070527,-0.01945544,-0.051418075,-1.550650111,-0.070933509,-0.099982864,0.028796285,-0.08289929900000001,-0.027657957,-0.068483097,-0.01684759,-0.02206329,-0.007364113,-0.095472037,-1.65569067,-1.4456095519999999,0.849189535,1.323058377,-10.58668431,-8.32005513,-11.64706407,-10.15951344,-10.90376273,-11.90302619,-6.153452581,-2.214940636,-8.277117729187012,-13.065793991088867,-11.514760971069336,-8.901142120361328,-12.360891342163086 -1501,1501,Y103C,-0.031449683,-0.004988079,-0.013592198,-0.243704384,-1.8546371480000001,0.012208953,-0.066108271,0.0032089059999999997,-0.108491886,0.016853728999999998,-0.026829887,-0.007170897,-0.020013498,-0.24748156,-0.239927207,-1.733519566,-1.9757547290000002,0.5491867420000001,1.302912209,-11.38701479,-11.72793298,-12.8054844,-10.54441958,-12.32794434,-9.529292671,-8.146801337000001,-3.991393758,-9.911781311035156,-10.134592056274414,-11.661042213439941,-10.414039611816406,-10.514235496520996 -1502,1502,Y103E,-0.037127772999999996,-0.054230348,-0.10429649699999999,-1.571789792,-2.177651822,-0.034278309,-0.075840503,0.0015849570000000001,0.144534293,-0.060238365999999995,-0.048222329,-0.043725809000000004,-0.164867184,-1.3543603869999998,-1.789219196,-2.193434828,-2.161868815,0.69862739,0.714720758,-11.80405332,-9.769531105,-14.57684316,-10.9264632,-12.14618439,-11.60124477,-7.117992200000001,-3.8632711719999997,-10.899739265441895,-14.751241683959961,-12.951149940490723,-11.706389427185059,-13.007928848266602 -1503,1503,Y103D,-0.048571813,-0.051599948,-0.029027702000000002,-1.193106894,-2.22642002,-0.06489756599999999,-0.071144424,-0.025999202000000003,-0.037141808,-0.08915442900000001,-0.014045466000000001,-0.034058468,-0.023996935,-0.981147274,-1.405066514,-1.934761217,-2.5180788219999997,2.3347989680000003,1.642784759,-10.99473507,-9.986297546,-12.34714725,-9.618599854,-10.80920096,-12.21242976,-6.502266979,-2.8068862660000002,-8.928081512451172,-13.642472267150879,-11.131175994873047,-10.708861351013184,-11.144598007202148 -1504,1504,Y103G,-0.006398069,-0.033022067999999995,-0.011694527,-0.002136913,-1.5459105430000002,-0.071113114,-0.05603484,0.043238702000000004,-0.10568393699999999,-0.054181907,-0.011862228999999998,-0.017628366,-0.005760688000000001,-0.000602284,-0.003671541,-1.48655636,-1.605264726,0.6912788129999999,1.3205065740000002,-9.984625732000001,-7.996547371,-12.79886829,-7.766943932,-11.00894549,-10.35182359,-6.055454284,0.254467632,-8.349943161010742,-13.487759590148926,-10.955183982849121,-10.829627990722656,-11.552732467651367 -1505,1505,Y103F,-0.045050735999999994,-0.041058297,-0.044771949000000005,-0.034330937,-0.238752093,-0.022781127999999998,-0.06694679,-0.023154681,-0.074633618,-0.056662684000000005,-0.02545391,-0.050134097999999995,-0.039409799,-0.07701000000000001,0.008348125999999999,-0.244799734,-0.232704452,1.199372656,1.9343194019999999,-5.768057954,-6.4995058210000005,-6.101388039,-5.32119944,-6.51408326,-4.4041132130000005,-6.009323404,-3.106451295,-4.722515106201172,-7.736685752868652,-6.986905097961426,-5.119174003601074,-8.581337928771973 -1506,1506,Y103I,-0.147854871,-0.09985103,-0.068676027,-0.764696548,-1.6357210290000002,-0.006047783,-0.178659375,-0.117050366,0.018483406,-0.09750506099999999,-0.10219699900000001,-0.049491337999999996,-0.08786071599999999,-0.493271355,-1.0361217409999999,-2.005761697,-1.265680361,1.6911397519999998,1.386271377,-11.30654185,-8.648484047,-12.92415092,-11.10504298,-11.55747438,-12.29755692,-7.217696664,-3.521978162,-8.883561134338379,-12.25743293762207,-12.556568145751953,-8.699225425720215,-12.660566329956055 -1507,1507,Y103H,-0.016535564,-0.00847579,-0.016529294,0.01321681,-0.782617213,-0.011871137,-0.017445498,-0.01562563,0.056904851,-0.0434239,0.02647232,-0.039347923,0.0062893359999999995,0.010275873,0.016157747,-0.67372613,-0.891508295,0.613258414,1.381434036,-3.808133841,-3.47374173,-5.321738358,-3.615427513,-3.204600006,-3.4251615980000003,-4.120502916,-0.90385354,-4.879298210144043,-7.425022125244141,-6.076852798461914,-4.819724082946777,-6.263049602508545 -1508,1508,Y103K,-0.069037223,-0.113006186,-0.553997919,-1.871682074,-2.536416425,-0.018804023,-0.127481271,-0.010593173999999999,-0.077604858,-0.117575044,-0.10843732800000001,-0.52075424,-0.587241597,-1.5583683080000001,-2.18499584,-2.73703614,-2.33579671,1.954938064,0.988051508,-11.28729712,-10.58492824,-12.92426598,-10.82130459,-11.63867317,-10.4673136,-8.318440212999999,-5.258716045,-8.427242279052734,-14.431939125061035,-12.300924301147461,-10.06930160522461,-12.440553665161133 -1509,1509,Y103M,-0.0053095040000000005,-0.023037357,0.024612126,0.009628693,-1.746080843,-0.082411258,-0.024730126,0.014111118,0.06069784,-0.005694070999999999,-0.040380643,0.008437576,0.040786675,0.015908195,0.0033491909999999996,-1.427160737,-2.0650009480000002,0.562446154,1.317175385,-12.20713058,-10.73150129,-12.95494767,-11.89488287,-12.90501578,-12.54930528,-8.724300107000001,-5.714755152,-9.52324104309082,-13.227540969848633,-12.433805465698242,-9.706863403320312,-13.563929557800293 -1510,1510,Y103L,-0.087192536,-0.06105568,-0.031958366,-0.7956643290000001,-1.681825516,-0.027080824,-0.118948573,-0.05543649900000001,-0.015239967,-0.068464047,-0.053647312999999995,-0.024847422999999997,-0.039069308999999997,-0.580260711,-1.011067946,-1.8581998709999998,-1.5054511609999999,1.8607973269999998,1.472915086,-10.40651469,-9.098682419,-10.59733482,-10.39720757,-10.96252936,-10.97681927,-7.661885487999999,-4.341591415,-7.725893020629883,-12.766885757446289,-11.290603637695312,-8.950963973999023,-11.673583984375 -1511,1511,Y103N,-0.08645297699999999,-0.036985252999999996,-0.036149186,-0.010693496,-1.2467469999999998,-0.024792718,-0.123005756,-0.049900198,0.008723568000000001,-0.037613602999999995,-0.036356902,-0.024810927000000003,-0.047487445,0.056794352,-0.078181343,-1.214824002,-1.278669997,0.747634137,1.342288318,-7.378222765,-6.824054535,-9.145194984,-5.81346492,-6.776937836,-8.331461548,-4.472886572,-1.503383158,-4.879138946533203,-10.803353309631348,-7.565917491912842,-6.562796592712402,-8.788230895996094 -1512,1512,Y103Q,-0.043592799,-0.045826657,-0.03952644,-0.354801926,-1.936924464,-0.03371773,-0.075265659,-0.011919938,-0.027274085,-0.045574512000000005,-0.046078800999999996,-0.015686443,-0.063366436,-0.21147502,-0.498128832,-1.96167779,-1.9121711369999999,1.20062038,1.324761023,-11.90304338,-11.52050692,-13.53723603,-11.38730995,-11.38933994,-11.68082406,-9.067966532,-6.075925448,-8.775503158569336,-12.974020957946777,-11.945281982421875,-10.025703430175781,-11.157400131225586 -1513,1513,Y103P,-0.004184865,-0.061144263,-0.001596155,-0.029937283,-1.125442206,-0.057069363,-0.037174275,0.028804546,-0.068514641,-0.05106669,-0.071221836,0.015367712,-0.018560021,-0.034395245,-0.025479321,-0.966082843,-1.284801569,0.7074249029999999,1.359969576,-10.83940805,-7.163017395,-12.33770146,-10.80043841,-11.78328873,-12.11259427,-6.30387546,-1.7817100909999999,-10.713151931762695,-14.748729705810547,-14.336071968078613,-11.712447166442871,-13.245438575744629 -1514,1514,Y103S,-0.058107825,-0.076590034,-0.034134028,-0.039833439,-1.620639579,-0.032681068,-0.09996706,-0.016248589,0.035581861,-0.062493145,-0.09068692199999999,-0.035083324,-0.033184731,-0.011338403,-0.068328474,-1.4553269180000001,-1.785952239,0.7247356009999999,1.3248540290000002,-9.63598418,-8.463795852999999,-10.24886179,-8.527913765,-10.41395418,-10.52539531,-6.319579688999999,-2.09117894,-5.92189884185791,-10.793689727783203,-10.054112434387207,-9.201332092285156,-10.27461051940918 -1515,1515,Y103R,-0.02028246,-0.043373997000000004,-0.07010619400000001,-1.464283561,-1.838422416,-0.00010453200000000001,-0.077301829,0.036736909,0.00109809,-0.031883117999999995,-0.054864875,0.00035080800000000003,-0.140563195,-1.184431568,-1.7441355530000002,-1.9894081319999999,-1.687436699,2.458354126,1.6572561719999999,-10.73542044,-11.03280269,-12.70386889,-10.13294577,-10.26699504,-9.54048983,-7.799677558,-3.983543603,-8.118644714355469,-12.677352905273438,-10.691779136657715,-9.3326997756958,-11.588606834411621 -1516,1516,Y103T,-0.010662201999999999,-0.034830394,0.027119002000000003,-0.119636277,-1.557550548,0.012957308,-0.049716582999999995,0.028392179,0.103219487,-0.031605951,-0.038054836,0.064439774,-0.01020177,-0.051320695,-0.187951858,-1.5793232030000002,-1.5357778930000001,0.7529334459999999,1.320191275,-10.97757031,-8.37180751,-12.24469241,-10.87271519,-11.45687282,-11.9417636,-6.223895613,-2.6577404280000003,-8.283559799194336,-12.923595428466797,-10.492975234985352,-9.175277709960938,-12.328474998474121 -1517,1517,Y103W,0.026650333,-0.013341438,-0.015070132,0.002494321,0.054448019,0.217568471,-0.000215424,0.053516089,-0.148062535,-0.045086637,0.018403762,0.005861089,-0.036001353,-0.054417487,0.059406127999999996,-0.017988183999999997,0.126884222,1.335850987,2.63641595,-2.7808762939999996,-2.692244591,-2.950314125,-2.1908714369999998,-3.0442573389999996,-3.026693977,-3.139830358,-1.06000399,-5.750210762023926,-6.515911102294922,-5.488668441772461,-6.3537139892578125,-7.997187614440918 -1518,1518,Y103V,-0.044995515,-0.029783702000000002,-0.043812507,-0.06333829,-1.5513143180000002,-0.055253764000000004,-0.094090319,0.004099289,-0.005829544,-0.024153359,-0.035414045,-0.039152383,-0.048472630999999995,-0.014757913000000001,-0.111918667,-1.576667665,-1.525960971,0.729236708,1.320133166,-10.54808046,-7.623221611,-12.24046948,-10.05284627,-10.56325972,-12.260605199999999,-6.430711591000001,-3.203959217,-9.001449584960938,-13.82278060913086,-12.567476272583008,-9.169839859008789,-12.975902557373047 -1519,1519,S104A,0.035921052,0.018118762,0.017096871,-0.014351967,-0.593591064,0.068802933,0.027193207,0.044648895999999993,,0.000480532,0.035756992,0.019745831999999998,0.01444791,-0.052625741,0.023921808,-0.419099723,-0.768082404,1.313633597,1.7757726459999998,-4.2707539610000005,-4.417247551,-3.2077956239999996,-2.497953743,-6.3821848139999995,-4.848588073999999,-4.321525992,-1.355635287,-4.03823184967041,-5.536462306976318,-4.9418134689331055,-5.800593852996826,-7.1232781410217285 -1520,1520,S104C,0.035432832000000004,-0.015412063,-0.0197801,-0.098731414,-1.841876679,0.0340079,0.03818072,0.032684944,,-0.003788885,-0.027035241,-5.94e-06,-0.039554259,-0.045515719,-0.151947108,-1.8190314440000002,-1.8647219130000001,0.80679212,1.310245976,-10.84921473,-14.95272893,-10.73463311,-8.579851265,-11.2325713,-8.74628907,-9.480809609,-4.659014078999999,-9.168680191040039,-10.806229591369629,-10.153600692749023,-12.53614616394043,-9.733181953430176 -1521,1521,S104E,-0.027544314,-0.409092289,-1.571020499,-2.2332709790000003,-2.979643612,0.041909208999999996,-0.030372099,-0.024716527999999998,,-0.314545848,-0.50363873,-1.5286598919999999,-1.613381105,-2.09224261,-2.374299347,-2.555991576,-3.4032956469999998,2.8861150319999997,1.184170041,-10.75390518,-12.96542772,-9.28160685,-9.463875977,-11.23250611,-10.82610926,-8.530517577000001,-3.949012306,-11.075265884399414,-13.386049270629883,-9.715365409851074,-13.230573654174805,-13.448648452758789 -1522,1522,S104D,0.15883012400000002,-0.081482351,-0.389089631,-1.7840360240000002,-2.486833569,0.029174325,0.182312962,0.13534728599999998,,-0.020651869,-0.142312833,-0.23101442600000002,-0.547164836,-1.545955218,-2.0221168290000002,-2.524613999,-2.449053138,1.305800654,0.774063955,-11.26543315,-15.55046043,-10.29189278,-9.129799538,-12.32193037,-9.033082634,-8.457585883,-3.822061935,-10.839606285095215,-13.65749740600586,-9.901262283325195,-12.45745849609375,-11.46679401397705 -1523,1523,S104G,-0.0060993869999999995,0.001299559,0.023508868,-0.026190725,-1.652025149,0.059986738,-0.013330345,0.001131572,,0.028201469,-0.025602352000000002,0.021306734,0.025711001,0.0062181580000000005,-0.058599607000000005,-1.621801901,-1.682248397,0.464646141,1.304798765,-9.557354655,-12.44395766,-9.156423271,-8.626318481,-9.400219627,-8.159854232999999,-8.079238568,-2.2356804390000002,-8.002037048339844,-11.036447525024414,-7.901854515075684,-10.440414428710938,-10.648816108703613 -1524,1524,S104F,-0.18563390899999999,-0.199477848,-0.503831788,-1.773839444,-2.326121992,0.031715686,-0.169869556,-0.201398262,,0.002994447,-0.401950143,-0.159468745,-0.8481948309999999,-1.525562059,-2.0221168290000002,-2.203190845,-2.449053138,1.024732693,0.7361813970000001,-12.64700634,-17.74628269,-13.21569376,-10.16850558,-11.77845152,-10.32609816,-8.277692576,-4.703870248,-11.120777130126953,-15.150298118591309,-12.621993064880371,-11.57863712310791,-14.061040878295898 -1525,1525,S104I,-0.047671754000000004,-0.022634931,-0.964136742,-1.57694742,-1.89066934,-0.027957764,-0.057447377,-0.03789613,,0.075853672,-0.121123534,-0.816837218,-1.111436266,-1.608899265,-1.544995574,-1.809406796,-1.971931883,4.289146126,3.162138117,-13.418027599999999,-18.20587504,-14.84675288,-10.45207081,-11.6412735,-11.94416579,-9.300101527,-4.338774572,-10.883244514465332,-12.180743217468262,-13.172158241271973,-13.615898132324219,-14.405445098876953 -1526,1526,S104H,0.035223129,0.03480024,-0.11292147400000001,-0.061958087,-1.905650951,-0.001791635,-0.080928473,0.15137473099999998,,0.065785277,0.003815203,-0.24474045,0.018897502,-0.191704457,0.067788283,-1.839370019,-1.971931883,1.2538382190000001,1.342705562,-12.21860896,-16.61524598,-11.15589542,-9.581099411,-11.61285402,-12.12794998,-9.616698566,-5.833198987,-9.920369148254395,-14.492098808288574,-9.431991577148438,-11.234756469726562,-8.984413146972656 -1527,1527,S104K,-0.04281585,-0.008242985999999999,-0.45451961399999996,-1.8191688999999998,-2.464994769,0.046201794000000004,-0.042400784000000004,-0.043230915,,-0.005719175,-0.010766797,-0.28082681600000003,-0.628212412,-1.465976369,-2.172361431,-2.7456651460000003,-2.184324391,1.430574311,0.818752413,-12.17016467,-15.70732791,-9.583916588,-10.33060951,-12.29037216,-12.93859717,-10.65068302,-6.950523036,-10.370891571044922,-13.08753490447998,-9.76167106628418,-10.070616722106934,-13.558130264282227 -1528,1528,S104M,-0.018705375,0.019315543,-0.36639478700000006,-1.6522047480000002,-2.537879956,0.012366938000000001,-0.019045202,-0.018365547,,0.026327772000000003,0.012303313,-0.208517591,-0.524271983,-1.4526315980000002,-1.8517778980000001,-2.5240444319999997,-2.551715479,1.209853782,0.7692103840000001,-11.50950628,-15.27987972,-11.00421262,-9.434919487,-9.685558571,-12.14296103,-8.528150822,-5.104725364,-10.864326477050781,-13.72701644897461,-12.139525413513184,-13.337209701538086,-14.315433502197266 -1529,1529,S104L,-0.06336159599999999,-0.86970304,-1.760762665,-2.220868606,-3.01316915,0.04296991,-0.06381616400000001,-0.062907027,,-0.788318249,-0.95108783,-1.766019929,-1.755505401,-2.162495872,-2.279241339,-2.683338554,-3.342999745,3.157004253,1.15204559,-13.86177729,-18.65491854,-13.40665779,-12.31385849,-12.47566051,-12.45779109,-10.076600099999999,-6.315680945,-10.076875686645508,-14.267013549804688,-12.22661018371582,-11.928133010864258,-13.347243309020996 -1530,1530,S104N,-0.400913294,-0.036649293,-0.43066334700000003,-0.335987351,-1.206680947,0.244394077,-0.512292237,-0.289534351,,-0.107077012,0.033778426,-0.5737991689999999,-0.287527525,0.350142128,-1.022116829,-0.964308756,-1.449053138,0.307526788,1.321758068,-8.960142859,-13.09340082,-7.833773323,-6.174748207,-9.271837448,-8.426954497999999,-7.4400235189999995,-3.824945501,-7.868488311767578,-11.228151321411133,-7.19043493270874,-8.685091972351074,-7.154553413391113 -1531,1531,S104Q,-0.033022956,0.0008697510000000001,-1.187447634,-2.158699108,-3.1117978280000003,0.061076492999999996,-0.01094754,-0.055098372,,0.024965585,-0.023226082999999998,-1.101259813,-1.2736354540000001,-1.8320522030000002,-2.485346012,-3.311313335,-2.912282321,2.3317608990000003,1.008100322,-10.278331699999999,-12.94771544,-7.769069839,-9.451548195,-9.524731232,-11.69859379,-8.712483701,-3.1117475239999997,-8.400735855102539,-13.392566680908203,-9.997454643249512,-11.800488471984863,-13.16053295135498 -1532,1532,S104P,0.003832419,0.007738152,-1.156524794,-1.792250502,-2.4748801719999998,0.02312021,0.013706551,-0.006041714,,0.020601762,-0.005125458,-1.0734862520000001,-1.239563335,-1.7661636669999998,-1.818337336,-2.451761382,-2.497998961,2.781978492,1.4196419569999998,-10.82437539,-13.19598366,-10.20748555,-9.743901367000001,-11.35951141,-9.614994965,-8.36726091,-3.390519255,-11.72638988494873,-13.690360069274902,-11.988712310791016,-12.456714630126953,-13.37813949584961 -1533,1533,S104R,0.002650054,0.0022749289999999998,0.015895246000000002,-1.4876622080000002,-2.231699902,0.044020400999999994,0.002883609,0.002416498,,0.028431729,-0.023881871000000002,0.065062766,-0.033272274,-1.3046152709999999,-1.670709145,-2.240815613,-2.22258419,0.869032308,0.737209522,-13.51099261,-16.97633954,-12.99467189,-11.29788361,-11.99122461,-14.294843400000001,-9.662088652000001,-6.054136587,-10.363036155700684,-13.768865585327148,-10.140327453613281,-10.910270690917969,-13.896459579467773 -1534,1534,S104T,-0.062068205999999994,0.004185731,-0.012210634,-0.08759826,-1.7230472909999999,0.064780043,-0.063639215,-0.060497195999999996,,0.069014247,-0.060642786,0.016403975,-0.040825242000000005,0.008462064,-0.18365858300000001,-1.6782826819999999,-1.7678118999999999,0.583197104,1.306520317,-7.192254016000001,-10.0346138,-6.175500626,-4.8805513760000006,-7.205511215,-7.665093063,-7.429014361,-1.908054045,-7.8435468673706055,-9.824435234069824,-8.381686210632324,-9.660577774047852,-9.491158485412598 -1535,1535,S104W,0.02055038,-0.273629117,-1.45511843,-2.01250698,-2.463579428,0.044775612,0.022482069,0.018618691,,-0.222369467,-0.324888766,-1.536010609,-1.3742262509999998,-2.053371598,-1.9716423619999999,-2.679847861,-2.247310995,2.689127978,1.051204027,-15.0361096,-20.269728399999998,-15.45347575,-13.09120722,-13.43962217,-12.92651444,-9.694247609,-4.4334584580000005,-12.166400909423828,-15.891603469848633,-11.716842651367188,-14.986308097839355,-15.104735374450684 -1536,1536,S104V,-0.023832545,0.011478471,0.038511949,-1.476238065,-2.203338277,0.042430237,-0.011585763999999998,-0.036079326,,0.013594938,0.009362003,0.063768818,0.01325508,-1.24213729,-1.710338839,-2.372063747,-2.0346128059999997,0.329774976,0.7011623229999999,-13.03162991,-16.17375417,-14.94351566,-10.42150915,-11.68589626,-11.93347433,-8.990094367000001,-4.895315078,-8.916293144226074,-12.165037155151367,-11.268621444702148,-12.248331069946289,-13.502153396606445 -1537,1537,S104Y,-0.081882709,0.0079623,-0.16598291099999998,-1.4777635930000002,-2.140970515,-0.020740685,-0.035170982,-0.128594436,,0.15823743199999998,-0.142312833,-0.07440152,-0.25756430199999997,-1.167493562,-1.788033623,-2.0669710980000002,-2.214969932,2.349526989,1.5664599259999998,-14.07012977,-18.81313107,-15.26193134,-10.65555508,-12.76551349,-12.85451786,-9.184094847,-5.4861321720000005,-11.878035545349121,-15.024272918701172,-12.06364917755127,-12.325830459594727,-13.523336410522461 -1538,1538,P105A,-0.01793208,0.008901083,-0.040817482999999995,-0.018949929,-1.6179086969999998,0.021493397,-0.029878114,-0.005986046,0.0008598869999999999,-0.010356597,0.028158763,-0.06274459,-0.018890375,-0.011694649,-0.026205209,-1.792601219,-1.443216175,0.653236191,1.306784194,-8.183916423,-8.63088575,-9.11003083,-10.44609914,-8.430067252999999,-4.302499138,-5.997965991,-3.330149169,-9.453947067260742,-9.274930953979492,-8.208599090576172,-10.39236068725586,-7.654768943786621 -1539,1539,P105C,-0.003247222,-0.027213308,-0.156932129,-1.693777268,-2.263977654,0.066878325,0.027371267,-0.03386571,0.04389451900000001,-0.031578237,-0.022848379,-0.089038675,-0.224825582,-1.517709711,-1.869844825,-2.855021585,-1.6729337219999998,0.856676489,0.7147178590000001,-14.88022422,-14.70212283,-14.73780418,-17.87968893,-14.76103816,-12.320466999999999,-10.61968155,-9.88449642,-13.656482696533203,-15.17685604095459,-13.620680809020996,-16.65039825439453,-13.34652328491211 -1540,1540,P105E,-0.004942236,-0.050056475999999996,-0.009415334000000001,-0.036943107,-1.507607725,0.030061054,0.019804276000000003,-0.029688747999999997,0.064515055,-0.096569729,-0.003543223,-0.006279066,-0.012551601,-0.001497794,-0.07238841900000001,-1.5834356319999998,-1.4317798169999998,0.606928577,1.312592777,-10.54013443,-10.52849612,-11.07244686,-13.268897,-10.28899707,-7.541835121,-7.016667927,-3.967445298,-12.743846893310547,-13.844590187072754,-11.876592636108398,-13.727556228637695,-12.197842597961426 -1541,1541,P105D,-0.048215585,0.07212915,-0.034812273,-0.8626459040000001,-2.270477617,0.050233417,-0.011999425,-0.084431744,0.010327171999999999,0.014818333000000001,0.129439966,-0.06967414599999999,4.96e-05,-0.49226908,-1.233022727,-1.816868989,-2.7240862439999995,1.768289681,1.463445281,-10.89308444,-11.15907339,-11.16458569,-13.01095358,-11.46224634,-7.668563187,-6.594177009,-3.079261978,-12.421741485595703,-14.434741973876953,-12.451552391052246,-13.314170837402344,-12.380369186401367 -1542,1542,P105G,0.008789975,0.010468704,-0.026467088,-0.425160692,-1.889083431,0.022891032999999998,0.013724921999999999,0.003855028,0.02270522,-0.006954765,0.027892173,-0.007628245,-0.04530593,-0.237995142,-0.612326241,-1.6710809580000001,-2.107085903,1.313787267,1.3714449180000001,-12.00755628,-12.47442097,-12.92191518,-15.30946496,-11.75772208,-7.574258202,-6.851037865,-0.630004765,-12.287881851196289,-12.628265380859375,-11.705048561096191,-12.56331729888916,-11.542884826660156 -1543,1543,P105F,-0.015090107,-0.027415165,0.023680786000000002,-0.095615566,-2.0273263480000003,0.025645585,0.002295461,-0.032475673999999996,-0.043255655999999996,-0.038697978,-0.016132351,0.032162752999999995,0.015198818000000001,-0.039661467,-0.151569665,-1.884984809,-2.1696678869999997,0.8318095940000001,1.307575097,-14.26118269,-13.59833581,-13.978176199999998,-17.97867885,-14.02339073,-11.72733187,-8.565743591,-6.298960888,-12.979974746704102,-13.592942237854004,-13.593820571899414,-14.22202205657959,-12.64031982421875 -1544,1544,P105I,-0.008752117,-0.012170381999999999,-0.001040544,-0.034353356,-1.902309225,-0.008400742,0.00365764,-0.021161872999999998,0.08168308,-0.08863103300000001,0.06429027,0.019534354,-0.021615442000000002,0.0032592429999999998,-0.071965954,-1.38472072,-2.419897729,0.768160347,1.3320777,-12.55220648,-12.70648557,-12.95246433,-16.00149257,-11.62581812,-9.474771797,-7.561118542999999,-4.414047246,-12.20463752746582,-12.911571502685547,-12.581949234008789,-13.215008735656738,-11.377091407775879 -1545,1545,P105H,-0.034821038,-0.06362712400000001,-0.08286858,-0.058331701,-1.607758802,0.060519002,-0.014137245,-0.055504831,-0.078896013,-0.068193696,-0.059060550999999996,-0.10008114800000001,-0.065656012,-0.032536578,-0.084126823,-1.5599545369999999,-1.655563066,0.848508299,1.327273592,-13.24771158,-13.52739177,-13.37306887,-15.76852309,-13.58653336,-9.983040802,-9.508189892,-7.090362469,-11.465531349182129,-12.270641326904297,-9.803570747375488,-13.541398048400879,-10.907404899597168 -1546,1546,P105K,0.040550578999999996,0.00962138,-0.021786681000000002,0.037860859,-1.4479402959999998,0.045619462,0.0744963,0.006604857,0.155469294,-0.046635425,0.065878185,-0.013858568,-0.029714794,0.024146874,0.051574844,-1.662616879,-1.233263712,0.77572445,1.316325833,-10.23545316,-9.995317497,-10.48635027,-13.57657024,-9.324647857999999,-7.794379921,-6.650368512999999,-4.325334746,-11.861413955688477,-11.229273796081543,-9.907679557800293,-12.495097160339355,-11.031778335571289 -1547,1547,P105M,0.122141858,0.04944902599999999,0.030785725,0.022184932,-1.9629404069999998,0.040343132999999996,0.155564595,0.088719121,0.044770997,-0.067716555,0.166614606,-0.032457401000000004,0.09402885,-0.06282062,0.107190484,-1.5896252069999999,-2.336255606,0.9101248279999999,1.3311503709999999,-13.82033204,-13.43462017,-13.77744794,-17.26417176,-13.09853311,-11.52688721,-9.179539672999999,-6.5140615120000005,-12.909063339233398,-12.660628318786621,-13.414986610412598,-13.899789810180664,-12.74350357055664 -1548,1548,P105L,-0.000146894,0.024546652000000002,0.002379128,0.013450585,-1.565477837,-0.001078468,0.004017436,-0.004311223,0.127936624,-0.027172626000000002,0.07626593,-0.018925075,0.02368333,0.018861468,0.008039702,-1.4768918690000001,-1.654063804,0.5972854999999999,1.318263149,-11.96882571,-12.10523785,-11.78603197,-15.72969044,-10.91333083,-9.309837486000001,-7.408650284,-4.587375,-10.101839065551758,-10.21955394744873,-10.241954803466797,-9.111590385437012,-10.407918930053711 -1549,1549,P105N,-0.083502704,-0.015762916000000002,-0.040035207,-0.22099803,-1.957567679,0.035630603,-0.053848966,-0.113156441,-0.178729064,-0.019346431,-0.0121794,-0.023561581,-0.056508832,-0.12832870400000002,-0.313667355,-1.823522141,-2.091613217,0.9691458279999999,1.3203851979999999,-12.71966361,-12.73664458,-13.02183746,-15.66556982,-11.96531635,-10.20894983,-7.638092331,-5.3953385879999995,-13.03661823272705,-13.573540687561035,-12.229247093200684,-13.783379554748535,-12.25262451171875 -1550,1550,P105Q,-0.034140925,-0.031030927000000003,-0.04710361,-0.026478542,-1.620682791,0.063970795,0.028791631,-0.09707348,0.100166486,-0.024903144,-0.03715871,-0.033331187000000005,-0.060876032999999996,0.014467916,-0.067425,-1.6138897330000002,-1.6274758480000002,0.6504015360000001,1.312397861,-9.577311671,-9.445240051,-9.778481895,-12.07261974,-9.866071952999999,-6.7241447139999995,-6.588568177999999,-4.46282686,-11.618307113647461,-10.749682426452637,-10.490596771240234,-12.267459869384766,-10.397138595581055 -1551,1551,P105S,-0.040579613,-0.025237115,-0.033118125,-0.06258959,-1.694489614,0.024509592,-0.040606891,-0.040552335,0.011467551999999999,-0.00017398900000000002,-0.050300240999999996,-0.019973372,-0.046262877,-0.024961666,-0.10021751300000001,-1.698921395,-1.690057832,0.831963219,1.318474828,-9.712549828,-9.962574844,-9.112677452,-12.19323353,-9.532037682,-7.762225632000001,-6.640053631000001,-3.651936122,-9.945098876953125,-8.953869819641113,-8.873530387878418,-10.708602905273438,-9.38750171661377 -1552,1552,P105R,0.045418584000000005,0.01942966,0.016155349,-0.044201782,-1.6710997090000002,0.039525246,0.068929411,0.021907756,-0.048650688,-0.047185310999999994,0.08604463,-0.045853353,0.07816405,-0.050417022,-0.037986541,-1.681403824,-1.660795593,0.8207807220000001,1.318541315,-10.10178597,-9.360484497,-10.90127403,-13.17317694,-10.43359133,-6.640403046,-7.351476984,-4.6064639739999995,-12.324148178100586,-10.679473876953125,-9.529735565185547,-12.891057014465332,-10.879725456237793 -1553,1553,P105T,0.014060598,0.038445465,0.061955485,0.03068217,-1.455280832,0.056494915,0.012057018999999999,0.016064177,0.038217387,-0.023514036000000002,0.100404965,0.05708936,0.06682161,0.070491659,-0.009127319,-1.718134206,-1.192427458,0.5819789879999999,1.304089222,-10.24096958,-10.31091234,-9.775470108,-13.49628687,-10.07843818,-7.543740417,-7.4750709429999995,-2.9609316989999996,-11.123526573181152,-11.146829605102539,-8.954755783081055,-11.90888786315918,-10.372737884521484 -1554,1554,P105W,0.032360781,-0.055141447999999996,0.02921437,-0.731199387,-2.167596652,0.04794837,0.052428750999999996,0.012292811,-0.011873291000000001,-0.029638052,-0.080644843,0.003866653,0.054562085999999996,-0.41803907700000004,-1.044359696,-2.135562193,-2.199631111,1.6575167030000002,1.3511945719999998,-13.63342761,-13.10945093,-13.421378299999999,-16.37908466,-14.3500128,-10.90721134,-8.196340755,-5.569952545,-14.761320114135742,-14.58340072631836,-13.796913146972656,-15.93580436706543,-14.036970138549805 -1555,1555,P105V,-0.03579981,0.006636146999999999,0.0014376039999999999,0.014043222,-1.432323505,0.041421935,-0.046972917999999995,-0.024626701,0.046324825,-0.028337317999999997,0.041609611,0.012585421999999999,-0.009710215,0.001405051,0.026681392999999998,-1.365870046,-1.498776963,0.599050698,1.321589945,-9.777717067000001,-10.26856075,-10.84065807,-13.58177478,-9.254183716,-4.94340802,-5.993720357000001,-3.790407145,-11.40368366241455,-12.436971664428711,-11.504220008850098,-12.262194633483887,-9.834552764892578 -1556,1556,P105Y,0.031035067000000003,0.0014041720000000002,0.023190147,-0.134138557,-1.3968637019999999,0.012416606,0.064431481,-0.002361348,-0.121560425,-0.038315298,0.041123641,0.0072918919999999995,0.039088402,-0.08627446400000001,-0.18200265,-1.666624387,-1.127103017,0.849128068,1.32312655,-15.22312528,-14.38848096,-15.70768102,-18.72192557,-15.12502209,-12.17251678,-9.505755045,-7.03838871,-13.790055274963379,-13.708839416503906,-13.80653190612793,-14.729649543762207,-12.804736137390137 -1557,1557,V106A,0.040560795,0.18978977800000002,0.05272310400000001,0.12201680699999999,-0.23832878300000002,0.014438517,0.040968802,0.040152787999999995,0.057991947,0.183870647,0.19570890800000001,0.09020624,0.015239967,0.140931052,0.103102562,-0.122624184,-0.35403338100000004,1.101621924,2.144464447,-5.701955237999999,-7.02722979,-4.338239243,-5.603826057000001,-6.840277832000001,-4.70020327,-5.424723595,-2.450906467,-6.879888534545898,-8.640217781066895,-8.337984085083008,-7.5938520431518555,-7.141441345214844 -1558,1558,V106C,0.095390719,0.18561348100000002,0.066945423,0.18316066399999997,-0.574227852,0.00959463,0.104850741,0.08593069699999999,-0.025554103999999998,0.16125362599999998,0.209973336,0.055599134,0.078291712,0.154393291,0.21192803600000001,-0.291523585,-0.856932118,0.576778308,1.495597345,-11.4135125,-12.19720108,-11.04635215,-11.60421555,-11.82806252,-10.39173122,-9.17493518,-6.285610929,-11.652580261230469,-12.875044822692871,-10.843585014343262,-10.817355155944824,-11.120543479919434 -1559,1559,V106E,-0.045490607999999995,0.078293317,-0.013876798999999999,0.154010643,-0.040876561,0.069304225,-0.049999017,-0.040982199,0.192690521,0.096855484,0.05973115,0.001738438,-0.029492035,0.195882644,0.112138642,0.055850389,-0.13760351,1.118471852,2.9533257689999997,-7.372525443,-8.426553795,-4.822429672,-9.183023087,-8.542620766,-5.887999893,-5.094661904,-2.784845348,-7.578766822814941,-10.33410930633545,-9.293671607971191,-9.328807830810547,-6.812694549560547 -1560,1560,V106D,0.018907755,0.14018281400000002,0.07019709,0.11972428199999999,-1.664693309,-0.011591976,-0.01952214,0.05733765,0.11489679800000001,0.192935816,0.087429812,0.013788284,0.126605896,0.13469857400000002,0.10474999,-0.6650040389999999,-2.664382579,0.489439367,1.363883,-10.54778447,-11.78373557,-7.638732864,-12.20328477,-11.33802912,-9.775140007000001,-8.058163798999999,-4.456255854,-8.8330078125,-11.993602752685547,-9.954973220825195,-9.34883975982666,-8.563142776489258 -1561,1561,V106G,0.037119413,0.17474641,0.054450665999999995,0.11300327,-1.5154157730000002,0.014906618,-0.024547192000000002,0.098786018,0.086868075,0.195341885,0.154150935,0.073099206,0.035802125,0.19328009,0.032726449,-1.4389996330000001,-1.591831912,0.328642421,1.306471454,-8.318537059,-10.59705386,-5.633266159,-8.947756859,-8.463771027,-7.950837395,-6.675999319,-2.5362375530000003,-10.65138053894043,-13.305741310119629,-11.187911987304688,-11.85981559753418,-10.437362670898438 -1562,1562,V106F,0.053303364000000006,0.101230158,0.032783343,0.078542269,-1.1384707809999999,-0.007803182,0.024480622999999996,0.082126105,0.054096902999999995,0.164477221,0.037983094,0.057388574000000005,0.008178112,0.14903748,0.008047057,-0.878593317,-1.3983482440000001,0.356557736,1.3317311729999999,-7.57816237,-9.437637642,-7.9231914670000005,-7.336012993,-7.450210274,-5.743759476,-6.735900841,-2.269551622,-8.755050659179688,-10.475236892700195,-7.802919864654541,-10.057098388671875,-8.146117210388184 -1563,1563,V106I,-0.038204822,0.08512014300000001,0.036216752000000005,0.092675555,0.001953832,-0.006124785,-0.09843388900000001,0.022024246,0.04026318,0.09956983400000001,0.07067045200000001,0.032208235,0.040225269,0.174314049,0.01103706,0.082596406,-0.078688742,1.069397567,2.918971567,-1.928670465,-2.01879039,-1.325958763,-2.587385971,-1.627889198,-2.083328003,-3.036344123,-0.32733436,-2.7443885803222656,-6.104261875152588,-3.472867488861084,-4.813485622406006,-2.868746757507324 -1564,1564,V106H,0.05111147,0.16640117699999998,0.060213377,0.10125576300000001,-0.99464539,0.049266485,0.019486581,0.08273635900000001,0.048121193,0.146213575,0.186588778,0.007686298,0.112740455,0.11788475300000001,0.08462677199999999,-0.818076881,-1.171213898,0.542891475,1.353302695,-11.70872025,-12.9881496,-10.76695895,-12.95914153,-11.91350249,-9.915848671000001,-8.589171902,-5.38961001,-10.370063781738281,-11.168909072875977,-9.152250289916992,-11.028910636901855,-9.163451194763184 -1565,1565,V106K,-0.022416564,0.068244584,0.013801155,0.03255497,-1.2857219579999999,-0.043217035,-0.121342751,0.076509623,0.023229841,0.095368682,0.041120486,0.037916448,-0.010314138,0.044573633,0.020536306,-0.988820006,-1.58262391,0.538657146,1.340835155,-10.03726227,-11.63066222,-8.182264084,-10.59329633,-10.58338097,-9.196707748,-7.425147137000001,-4.480806335,-9.452013969421387,-11.02362060546875,-9.76215934753418,-11.766170501708984,-5.701876640319824 -1566,1566,V106M,0.018275968,0.154644426,0.077251632,0.151870635,-0.066307304,0.0026703309999999997,0.000716339,0.035835596000000004,0.076475353,0.138574339,0.170714513,0.06357037900000001,0.090932885,0.173632552,0.130108718,-0.018783229,-0.11383137800000001,1.1133497190000001,2.638047589,-6.0580706410000005,-6.517654952999999,-4.64036293,-6.356912932999999,-6.285455025,-6.489967361000001,-6.449590132000001,-2.122691734,-7.490365505218506,-10.783533096313477,-8.81884765625,-8.290876388549805,-7.4212646484375 -1567,1567,V106L,0.06579748,0.120793762,0.054859487,0.109243264,-0.040586891,-0.022521454,0.024085374,0.10750958599999999,0.078859666,0.130599768,0.110987755,0.026873334,0.08284564,0.142274404,0.076212124,0.011156991000000002,-0.09233077199999999,1.212728392,2.8225668219999998,-4.591312445,-4.857283875,-4.498529448999999,-5.494381392999999,-4.183022606000001,-3.9233449019999997,-4.260422238,-1.00123857,-6.658877372741699,-9.580814361572266,-6.168058395385742,-8.398039817810059,-6.4758100509643555 -1568,1568,V106N,0.092335189,0.075597901,-0.002360615,0.15467567,-1.48746731,0.001060436,0.014133483,0.170536895,0.15241316,0.11169484699999999,0.039500955,-0.036228808,0.031507579,0.11195425199999999,0.197397087,-1.35644212,-1.6184925,0.620200026,1.32363291,-11.01460307,-12.41450238,-10.39368602,-11.37867662,-10.79963863,-10.086511699999999,-7.946479098999999,-4.270069712,-9.860754013061523,-12.420429229736328,-8.965560913085938,-9.858275413513184,-8.361029624938965 -1569,1569,V106Q,0.035560325,0.14824673300000002,0.060772217999999996,0.108465892,-0.356222844,-0.006471353000000001,0.022079391,0.049041258,0.191679357,0.12427853,0.172214935,0.054275468,0.067268967,0.08089040900000001,0.136041375,-0.144747455,-0.567698232,1.321153482,2.238630195,-9.838776402,-10.8736351,-8.337720718,-11.14127032,-9.958999893,-8.882255974,-7.390567423999999,-4.7616395019999995,-9.566094398498535,-11.338438987731934,-10.272229194641113,-11.260612487792969,-8.052103042602539 -1570,1570,V106P,0.022797027,-0.19078191600000002,-1.4618041609999999,-1.907458094,-2.620729962,-0.0022780020000000003,0.008832164,0.03676189,-0.01570408,-0.06470804599999999,-0.316855785,-1.4290291769999999,-1.494579144,-1.69198461,-2.1229315769999997,-2.317878725,-2.923581198,3.660230465,2.15179342,-11.15417601,-12.37912146,-9.915035973,-10.79244738,-12.06138328,-10.62289198,-8.573551377000001,-5.478402787,-10.6831636428833,-11.774717330932617,-12.397139549255371,-12.955376625061035,-10.609062194824219 -1571,1571,V106S,-0.034340377000000005,0.108590195,0.010243626,0.083424601,-0.661677651,0.022091406,-0.07579789599999999,0.007117143,0.066721778,0.127936661,0.08924372800000001,0.018683155,0.001804096,0.12156485300000001,0.045284349,-0.44641912100000003,-0.87693618,0.571257879,1.419403244,-8.62546194,-9.891206687999999,-7.901045302999999,-7.785063843,-9.732408859,-7.817585007000001,-7.158087085,-2.683060737,-9.312785148620605,-11.322121620178223,-9.67142105102539,-8.689805030822754,-8.769876480102539 -1572,1572,V106R,0.086768315,0.127891355,0.030298517999999997,0.113624196,-1.148098026,0.044831746,0.08995515300000001,0.083581477,0.046410074,0.088886555,0.166896154,0.012933317,0.047663718,0.140662371,0.08658602,-1.1098636990000001,-1.186332352,0.61273723,1.337322484,-9.264624138,-10.62744516,-7.433961142999999,-10.2561225,-9.743552337999999,-8.262039551,-6.508300501,-3.4758065360000003,-10.065083503723145,-11.850897789001465,-9.800270080566406,-11.736331939697266,-7.357342720031738 -1573,1573,V106T,-0.004166725,0.106082551,-0.014765833999999999,0.115543503,-0.284868942,-0.034643658,-0.021251434,0.012917985,-0.008954843,0.181032778,0.031132324,-0.010257981,-0.019273687,0.145199646,0.08588735900000001,-0.146097329,-0.423640554,1.3574336219999998,2.301876832,-6.204095334,-7.140181694,-5.3237036589999995,-5.8147351910000005,-7.298429619,-5.443426506000001,-6.224109532000001,-2.204239832,-6.638824462890625,-10.017008781433105,-8.367420196533203,-8.58404541015625,-6.74585485458374 -1574,1574,V106W,-0.111445906,0.078158987,0.01277218,0.019560071000000002,-0.962883795,0.006305862,-0.146808215,-0.07608359599999999,-0.218214465,0.16117409300000002,-0.00485612,0.169597638,-0.144053279,0.157294513,-0.11817437199999999,-0.48785784200000004,-1.437909748,0.42523862,1.3818396240000002,-10.81550948,-12.79052549,-9.126807677999999,-11.26203549,-11.06705296,-9.831125771,-8.076518254,-4.633024309,-12.835166931152344,-13.878873825073242,-10.510924339294434,-14.104503631591797,-11.228812217712402 -1575,1575,V106Y,0.028857358,0.095952232,0.051393241,0.12173597900000001,-0.819350791,0.034884699,0.007312598000000001,0.050402117,0.017874723999999998,0.164607268,0.027297196,0.05449699,0.048289492,0.195366255,0.048105702,-0.5116987510000001,-1.127002831,0.419289265,1.376233981,-9.286566808,-11.21969217,-9.678760376,-9.05721402,-8.415551308,-8.061616165,-7.091078836,-2.7373396480000003,-10.009142875671387,-11.841436386108398,-8.752312660217285,-10.808324813842773,-9.038626670837402 -1576,1576,T107A,-0.006745241999999999,0.010280365,0.013892705,-0.046326133,-0.089299781,-0.026221223,-0.010337358,-0.003153125,0.036724017000000005,-0.032239185,0.052799914,0.018056459,0.009728951,-0.05004147900000001,-0.042610786,-0.046455530999999994,-0.13214403,1.412415236,2.5001693019999998,-3.9042093280000003,-4.29679451,-4.384091667,-2.63400798,-4.140134941,-4.06601754,-4.34101915,-1.28344751,-7.841825485229492,-11.672078132629395,-7.034846305847168,-8.48048210144043,-8.042945861816406 -1577,1577,T107C,-0.046131949000000005,0.06085215099999999,0.023562797000000003,-0.006236448,-0.246232592,0.090840326,-0.06875782,-0.023506078,-0.10464663800000001,0.08510345300000001,0.036600848,0.091749735,-0.044624141,0.040800355,-0.05327325,-0.104049641,-0.388415542,1.191664345,2.182603877,-8.184400816,-8.692845314,-8.618500549,-7.138534439,-6.513374069,-9.95874971,-6.542029009,-4.333888698,-11.996288299560547,-15.457797050476074,-8.485158920288086,-12.944389343261719,-10.551326751708984 -1578,1578,T107E,0.070681838,-0.631584843,-1.871881046,-2.0665628259999997,-2.6513373319999998,0.054069537,0.125920969,0.015442707,-0.065728571,-0.71560066,-0.547569026,-1.605759241,-2.13800285,-2.20330164,-1.929824011,-2.676197619,-2.626477045,2.91840322,1.046559996,-11.18889634,-11.18801355,-11.73426835,-10.21353255,-10.90371111,-11.90495614,-7.997672378,-5.417052637,-12.392450332641602,-19.178417205810547,-11.583623886108398,-14.757777214050293,-13.648811340332031 -1579,1579,T107D,-0.029319077000000002,-0.58983647,-1.88319168,-2.301452476,-2.735711985,0.040869295,-0.024600092999999996,-0.03403806,-0.139157489,-0.657174635,-0.522498305,-2.360246573,-1.4061367869999999,-2.258818968,-2.3440859830000003,-2.731714947,-2.739709022,0.8326989379999999,-0.459474108,-10.77704053,-11.25618,-13.08950011,-9.836159431,-10.01746719,-9.685895897,-8.043100848,-4.503289572,-12.395055770874023,-19.23834228515625,-10.13408088684082,-14.480413436889648,-15.216119766235352 -1580,1580,T107G,-0.08176576599999999,0.0040735979999999995,-0.018747262,-0.39933271,-1.84055421,0.047757680999999996,-0.072971643,-0.090559888,-0.134083124,0.012279334,-0.004132139,-0.005657985,-0.031836538,-0.17513722,-0.623528199,-1.997982837,-1.683125582,1.130332825,1.3133351709999999,-9.883430327000001,-10.46779593,-9.145671265,-8.780298225,-9.765120949,-11.25826527,-7.630179922000001,-3.528947717,-11.343267440795898,-16.494281768798828,-10.993866920471191,-12.282915115356445,-12.574836730957031 -1581,1581,T107F,-0.052304069,0.06989519799999999,-1.102515441,-2.264042075,-3.0477865860000004,0.050149556,-0.015087841000000001,-0.089520296,0.118795855,0.051280162000000004,0.08851023400000001,-1.094313917,-1.110716964,-1.8621180309999998,-2.665966118,-3.033984015,-3.061589157,2.314948436,1.00319852,-10.96099193,-10.00413546,-13.30559003,-9.857818909,-8.631354546,-13.00606072,-6.666560358,-3.292247872,-13.858856201171875,-15.804725646972656,-12.2916259765625,-12.993948936462402,-14.372066497802734 -1582,1582,T107I,-0.038382055,0.011377337,0.01577585,-0.18761643600000003,-1.853374251,0.047886449000000005,-0.011256055,-0.06550805400000001,-0.040904987999999996,0.0012193269999999999,0.021535346,0.049542708,-0.017991008,-0.127972152,-0.247260719,-1.6836535019999999,-2.023095,0.964594829,1.330277399,-7.536819572000001,-6.877027892999999,-9.259155769,-6.864325478,-6.0935305479999995,-8.590058174,-5.366195426,-2.236196538,-9.529581069946289,-12.525717735290527,-9.572269439697266,-10.528820037841797,-9.94703197479248 -1583,1583,T107H,-0.15235711,-0.5895886920000001,-1.6006534680000002,-2.125854173,-2.992764396,0.020440643,-0.099608265,-0.205105955,-0.043452177,-0.555518187,-0.623659196,-1.552132099,-1.649174836,-1.965614309,-2.2860940359999997,-2.7017517239999997,-3.283777067,3.035158485,1.28948879,-13.29870722,-14.08022835,-14.36021736,-12.05296189,-11.68835439,-14.31177409,-8.190428629,-5.1853013830000005,-14.270509719848633,-18.361330032348633,-10.720600128173828,-14.63273811340332,-14.974953651428223 -1584,1584,T107K,-0.10607589,-0.8798790890000001,-1.856462104,-2.542279501,-2.826024012,0.081818737,-0.08632605300000001,-0.125825726,0.005627337,-0.8535523909999999,-0.9062057859999999,-1.81834459,-1.894579618,-2.620006972,-2.464552029,-2.791872956,-2.860175068,2.02188291,0.165689055,-11.29827376,-11.01718398,-13.43854657,-10.51215192,-10.65620234,-10.86728398,-7.673180941,-3.7253785,-12.56973648071289,-15.355559349060059,-8.785173416137695,-13.082558631896973,-12.096830368041992 -1585,1585,T107M,-0.051601632,0.002363175,-0.034747812999999995,-0.124915125,-1.95630099,0.012062908,-0.048998270999999996,-0.054204992,-0.112471975,-0.083563788,0.088290138,-0.032598527,-0.036897097999999996,-0.080140588,-0.16968966100000002,-1.6108927769999999,-2.301709203,0.912097357,1.330147775,-8.216527464,-7.041995087,-10.02701324,-7.393778656,-6.424787277,-10.19506306,-6.212597858,-2.572752913,-10.009580612182617,-12.973102569580078,-9.659059524536133,-10.107288360595703,-10.921699523925781 -1586,1586,T107L,-0.074287777,0.0062464719999999994,-0.043664057,-0.043679744000000006,-0.66359724,0.029544038999999998,-0.05293743099999999,-0.095638123,0.108238994,0.007016871,0.005476073000000001,-0.013739462,-0.07358865099999999,-0.038803311,-0.048556177,-0.455369717,-0.871824763,1.4639968819999998,1.857108215,-7.606464367999999,-6.389024582,-10.10613092,-6.134499817000001,-5.83137796,-9.571288559,-5.718375816,-0.767916582,-11.584126472473145,-14.560981750488281,-10.099038124084473,-11.17529582977295,-11.425904273986816 -1587,1587,T107N,-0.209311849,-0.050723141,-0.071298341,-1.337212398,-2.7090025389999997,0.06979353599999999,-0.19302995,-0.22559374699999998,-0.049934304000000006,0.017208892,-0.118655174,-0.011404798,-0.131191883,-1.226366944,-1.448057851,-2.495142941,-2.9228621360000004,0.649874505,0.7219526190000001,-9.746452257,-10.96557829,-11.53718527,-9.931805458,-9.699254951,-6.5984373089999995,-7.882789742000001,-3.9237075960000003,-11.20344066619873,-15.28054141998291,-9.573653221130371,-10.963183403015137,-11.845484733581543 -1588,1588,T107Q,-0.09114126,-0.645504764,-1.7177096,-2.224016025,-2.8087905319999997,0.045515108,-0.053032123,-0.129250396,-0.274612344,-0.578222977,-0.712786551,-1.546268334,-1.889150866,-1.9889087719999998,-2.4591232769999998,-2.762834748,-2.8547463160000004,3.0440825339999997,1.24977112,-11.11122651,-11.19680244,-11.948319699999999,-10.33884042,-9.571616608,-12.50055339,-7.3233043989999995,-2.593493499,-12.937821388244629,-18.044023513793945,-10.937026023864746,-13.407672882080078,-14.601022720336914 -1589,1589,T107P,-0.082385536,-0.7429915709999999,-1.623525057,-2.071185571,-2.692235412,0.014034158,-0.080294165,-0.08447690599999999,0.047424915,-0.69042979,-0.7955533509999999,-1.6385004769999998,-1.6085496369999999,-2.051518449,-2.090852692,-2.4480260830000002,-2.93644474,3.6758891119999997,1.831969524,-10.66188441,-9.054914162000001,-11.11852548,-10.11252228,-11.26722214,-11.75623798,-7.425574601,-5.195922235,-11.438919067382812,-15.852209091186523,-11.886804580688477,-14.293457984924316,-13.616033554077148 -1590,1590,T107S,-0.063023453,-0.002286058,-0.020659847,-0.037549822000000004,-0.120848921,0.006681967,-0.059511982000000005,-0.066534923,0.020251943999999997,-0.004162211,-0.000409905,0.005252621,-0.046572315,-0.056939616,-0.018160028,-0.06069739,-0.181000452,1.4947475909999999,2.571027563,-3.9436725630000002,-4.82815535,-3.7731485289999998,-3.93549456,-4.454940285,-2.7266240919999998,-3.861202154,-1.8308423319999998,-7.693305015563965,-10.269430160522461,-6.688429832458496,-7.549735069274902,-8.248069763183594 -1591,1591,T107R,-0.096467989,-0.91830941,-1.739487519,-2.12219694,-3.115506105,0.070291051,-0.079894087,-0.11304189099999999,0.062058008,-0.8710744359999999,-0.965544383,-1.5830487690000001,-1.8959262680000002,-2.0215332480000003,-2.222860631,-3.369490491,-2.861521718,2.956030648,1.082917297,-10.35652335,-10.3496273,-8.388540932,-10.63298698,-9.757784332,-12.65367719,-7.152128635,-1.416514441,-12.689038276672363,-15.398331642150879,-6.787391185760498,-12.158000946044922,-13.126358032226562 -1592,1592,T107W,-0.092796846,-0.20823349100000002,-2.018788625,-2.3155303959999998,-2.837835535,-0.056818785,-0.07478468099999999,-0.11080901,0.124150972,-0.170884898,-0.245582083,-1.9432833269999998,-2.094293922,-2.620006972,-2.0110538190000002,-2.791872956,-2.883798113,0.704593385,-0.107056604,-14.99517335,-14.28831615,-16.59741884,-13.52005363,-13.13989748,-17.43018063,-10.67972857,-9.388821529,-16.38482093811035,-18.53459358215332,-13.585973739624023,-16.70801544189453,-17.488447189331055 -1593,1593,T107V,-0.06609955299999999,0.055780315999999996,-0.020894247,-0.015299563,-0.579767453,0.040601554,-0.058921176,-0.073277929,-0.14086984,0.043549062,0.06801157,0.049542708,-0.09133120199999999,-0.012202251,-0.018396875,-0.35459478299999997,-0.804940123,1.213534075,1.7760240109999998,-6.503037901,-6.539518715,-8.185112671,-4.971032082,-4.6697944410000005,-8.149731597999999,-5.938536115,-2.713634532,-8.837060928344727,-13.830000877380371,-8.969367980957031,-10.090875625610352,-8.992619514465332 -1594,1594,T107Y,-0.122312517,-0.17789928,-1.342013136,-1.883432763,-2.7886962989999997,0.033194758,-0.12209441300000001,-0.12253062,0.089173388,-0.03812146,-0.3176771,-1.134937291,-1.54908898,-1.869652883,-1.897212642,-2.5855869119999997,-2.991805685,2.579685884,1.19681407,-13.25593437,-13.33255616,-15.33804868,-11.69383807,-10.44134105,-15.47388791,-8.388545527,-4.420660361,-15.243264198303223,-18.74817657470703,-12.465120315551758,-15.159444808959961,-15.368236541748047 -1595,1595,E108A,0.04423713,0.05940076,0.10152702400000001,0.064489462,0.055104957,0.007468575999999999,-0.017011613000000002,0.105485872,-0.223351347,0.074562435,0.044239084000000005,0.07769686599999999,0.12535718199999998,0.10360461300000001,0.025374311,0.04281331,0.067396603,1.056413169,2.781572971,-4.817972856,-5.24288578,-4.185154137,-5.720643462999999,-3.8765407260000004,-5.064640175,-4.751247602,-1.431641436,-6.359828472137451,-5.562902450561523,-4.991920471191406,-6.804612159729004,-7.301464080810547 -1596,1596,E108C,0.054647535,0.070085315,0.046737695,0.059532193,-1.1093403259999999,0.028800658,0.014324638999999998,0.094970431,-0.025339585,0.087268521,0.052902109,0.077734074,0.015741316,0.133154422,-0.014090036,-1.073348756,-1.145331895,0.476470085,1.326397574,-9.947922702,-10.626047,-9.115237099,-12.03734997,-9.39135051,-8.569628929,-7.924446742000001,-5.26608638,-12.224541664123535,-12.671404838562012,-8.524023056030273,-13.18265438079834,-13.214455604553223 -1597,1597,E108D,0.050245730999999995,0.07831624599999999,0.052930784,0.01712767,0.0069821990000000006,0.050361434000000004,0.042026169,0.058465293,-0.119420308,0.01310759,0.14352490199999998,-0.0028972390000000002,0.108758807,0.046746971,-0.012491631999999999,-0.025313459,0.039277856,1.148165013,2.480467834,-5.394160091,-6.159121452000001,-6.127450806000001,-4.525999634,-4.605263603,-5.552964958,-5.135150605,-1.269333176,-6.692591667175293,-7.491695404052734,-6.104809761047363,-8.360359191894531,-8.087075233459473 -1598,1598,E108G,0.029924597,0.050773349,0.016068095,0.046607315,0.010259220999999999,-0.011323511999999999,-0.0219643,0.081813494,-0.142452984,0.05974401,0.041802687000000005,0.042758412,-0.010622223,0.106598376,-0.013383746,-0.02113054,0.041648982,1.193938266,2.61408574,-4.171162999,-3.976314926,-3.64113588,-4.951774498,-3.597467308,-4.689122383,-3.3218777580000003,-1.152292359,-5.599814414978027,-5.973086357116699,-6.080211162567139,-7.993407249450684,-7.821561813354492 -1599,1599,E108F,-0.038087241,0.051248234000000004,0.028130652000000003,0.019042923,-0.26269804199999996,0.016159505,-0.084279746,0.008105264000000001,-0.011020003,0.102229291,0.000267176,0.071279352,-0.015018048,0.072847951,-0.034762106,-0.1685956,-0.35680048299999995,1.321788369,2.165848299,-10.0088961,-10.22869862,-9.456073737999999,-12.22584662,-9.875491913,-8.258369591000001,-6.313327502999999,-3.4283240669999997,-11.626371383666992,-12.144316673278809,-8.769576072692871,-12.091289520263672,-12.657630920410156 -1600,1600,E108I,0.062025548,0.062434922999999996,0.069933971,0.011138465,0.030259801,-0.027639242999999997,0.038953136,0.08509796,-0.184538487,0.034166685,0.09070316,0.10473664,0.035131301000000004,0.11542554199999999,-0.09314861199999999,-0.030945538999999998,0.091465141,1.543610422,3.106887046,-8.746913054,-8.267344162,-8.219911423,-10.51618153,-8.458154129,-8.272974022,-6.81128893,-3.6228542569999997,-10.145438194274902,-10.043368339538574,-7.804305076599121,-10.675264358520508,-10.148956298828125 -1601,1601,E108H,0.090265595,0.068075236,0.048499138,0.032717391,-0.082148876,0.00019596900000000002,0.018549665,0.161981525,-0.148419832,0.081476417,0.054674055,0.043498450999999994,0.053499825,0.08656918,-0.021134398,-0.038076016000000004,-0.126221735,1.671448915,3.643209181,-9.058062598,-10.42551437,-8.489283936,-10.21726593,-9.273630562000001,-6.884618195,-6.096879405,-2.44755244,-8.367568016052246,-8.967473030090332,-6.335675239562988,-9.389946937561035,-8.888643264770508 -1602,1602,E108K,-0.061698443,-0.03527386,0.076369076,-0.149806089,-0.05218598,-0.01648107,-0.16400082300000002,0.040603937,0.069635928,0.076918666,-0.147466386,0.18034532600000003,-0.027607175,-0.016236921,-0.283375257,-0.030691787999999998,-0.073680172,1.29941169,2.618994937,-2.106798457,-2.186979279,-1.4059729230000002,-2.9264690780000002,-2.754272484,-1.260298523,-2.115627396,-0.8956998840000001,-6.733218193054199,-5.614439010620117,-2.66957950592041,-5.920966148376465,-5.488805770874023 -1603,1603,E108M,0.08877214900000001,0.038777772,0.086781236,0.0077648330000000005,0.073928831,0.029826925,0.10870700300000001,0.068837295,-0.039508541,-0.0009912319999999999,0.078546776,0.08425293699999999,0.089309535,0.07262605400000001,-0.057096389000000004,-0.022489723,0.170347384,1.218791872,2.532598216,-8.469021992,-7.661807037000001,-7.236786781,-10.54538815,-8.935709282000001,-7.965418716,-6.805817773999999,-4.08540542,-9.972004890441895,-9.631708145141602,-6.776773452758789,-10.038857460021973,-10.440411567687988 -1604,1604,E108L,0.008678048,0.025322802999999998,0.015932696,0.010233584,-0.11248789699999999,0.002339014,-0.033913545,0.051269641,-0.195181895,0.04161799,0.009027616,0.048832887,-0.016967495,0.090947196,-0.070480029,-0.07624761599999999,-0.14872817800000002,1.133834381,2.326636976,-8.591837092999999,-8.73566259,-7.366637756,-10.66653706,-9.313436377999999,-6.876911682,-6.267414425,-3.562636949,-9.451379776000977,-8.420461654663086,-5.360625267028809,-8.910355567932129,-8.991994857788086 -1605,1605,E108N,0.0075842290000000005,0.012707598999999998,0.069950948,0.063434422,-0.012370212,-0.021528806,-0.060105682,0.075274139,-0.258832316,0.108064615,-0.082649417,0.107229619,0.032672276,0.132516613,-0.005647769,-0.004269147,-0.020471276,1.119145782,2.679590251,-7.43491279,-9.214789657999999,-7.1333882520000005,-8.098134254,-7.579346847999999,-5.148904938,-6.00527237,-2.414364831,-8.62362289428711,-8.761811256408691,-6.561588764190674,-8.377367973327637,-8.787050247192383 -1606,1606,E108Q,-0.074604371,-0.020977037999999996,-0.013693516999999999,-0.023986554,-0.029396715,-0.001302233,-0.143456413,-0.0057523290000000005,-0.1588434,0.047028569000000006,-0.088982645,-0.00892674,-0.018460294,0.039877355,-0.087850463,-0.011764212,-0.047029218,1.671448915,3.643209181,-3.832586317,-3.873794868,-3.199175758,-4.513622826000001,-3.4008967360000004,-4.175441398999999,-4.455707267,-0.8861070059999999,-6.829423904418945,-5.195380687713623,-3.9095983505249023,-5.498898983001709,-5.830052852630615 -1607,1607,E108P,0.025526204,0.043687102,0.072138572,0.038882905,-1.062669137,-0.017015042,0.004882365,0.046170042,-0.19732982699999999,0.054817354000000006,0.032556849,0.063647016,0.080630128,0.097471184,-0.019705375,-0.981395308,-1.143942966,0.36817852,1.3246697,-8.266399173,-8.056739136000001,-6.900642075,-9.11571946,-7.30249144,-9.956403755,-5.6551715410000005,-2.840339532,-9.263858795166016,-9.337666511535645,-7.66715669631958,-10.105934143066406,-10.81814193725586 -1608,1608,E108S,0.066924184,0.069532613,0.09196311199999999,0.040856756,0.054907278,-0.004265635,0.025985886,0.107862481,-0.173868352,0.09653791800000001,0.042527308,0.066484328,0.11744189599999999,0.100333164,-0.018619653,0.051277842000000004,0.058536713,1.192749345,2.8990608960000004,-3.7532092269999997,-4.338897964,-2.3932953340000003,-5.184978912,-3.884992271,-2.963881653,-3.199792064,-1.273824206,-6.890076637268066,-6.0706987380981445,-5.589757919311523,-7.892406463623047,-8.247780799865723 -1609,1609,E108R,0.052082248,0.044000145,0.043302612000000004,0.031351357999999996,-0.043445211,0.016199359,-0.013462402,0.11762689800000001,-0.127270399,0.060784877,0.027215412,0.060077782999999996,0.026527441000000002,0.078897439,-0.016194723,-0.015352352,-0.07153807,1.114053806,2.46394564,-4.9083773530000006,-6.642658577000001,-4.0830711289999995,-5.766293365,-4.092625381,-3.957238312,-3.6481892510000002,-1.4716025019999999,-6.813287734985352,-7.22600793838501,-2.938328266143799,-7.682829856872559,-7.042999267578125 -1610,1610,E108T,0.015862006,0.040637482,0.04021724,0.010824258,-0.02672906,0.018528503,-0.023118125,0.054842137,-0.10266234199999999,0.07327328799999999,0.008001675,0.043322022,0.037112458,0.092922385,-0.07127387,-0.008909354,-0.044548766,1.306881923,2.817773842,-5.2886713180000005,-6.871187172000001,-5.026187279,-6.4336660000000006,-4.507327255,-3.604988884,-5.186376055,-2.190113563,-8.200637817382812,-7.2156171798706055,-5.630911827087402,-8.529476165771484,-8.709670066833496 -1611,1611,E108W,-0.014283801,0.035825199999999995,0.019013858,0.055401382,-0.423567818,0.0347198,-0.0013858310000000001,-0.02718177,-0.43551405,0.079808194,-0.008157794,0.022076646000000002,0.015951069,0.12123530199999999,-0.010432539000000001,-0.389852841,-0.457282795,0.478564286,1.417825828,-10.55188933,-9.672628952,-9.927555717,-11.53928992,-10.20073944,-11.41923262,-6.383179094,-2.628107846,-11.824249267578125,-12.771608352661133,-8.878337860107422,-13.686346054077148,-13.560342788696289 -1612,1612,E108V,0.058347243,0.042376881,0.034249179,0.05983645,0.021242083999999998,-0.016108232,0.024756272000000003,0.091938214,-0.157816699,0.026484735,0.058269025999999995,0.041207892999999995,0.027290465,0.094391461,0.025281438,0.000470871,0.042013296,1.22191688,2.693886263,-8.081966182,-7.517504089,-7.391281372000001,-9.934244606,-7.481418242999999,-8.085382598999999,-6.827085286,-3.355521,-8.699875831604004,-8.05398178100586,-6.891324043273926,-8.971651077270508,-9.206182479858398 -1613,1613,E108Y,0.017741002,-0.014282467,0.058323004000000005,-0.031823613,-0.185633878,0.013022338999999999,0.01348771,0.021994293999999998,-0.285078926,-0.016231198,-0.012333735,0.079489147,0.03715686,0.090449739,-0.154096965,-0.103935605,-0.267332151,1.264393939,2.307717902,-9.676736302,-9.710886009,-9.791089394,-11.91658926,-9.4297323,-7.535384552000001,-6.7790771560000005,-1.4241448190000001,-11.427873611450195,-12.19709300994873,-8.871898651123047,-12.640359878540039,-11.852984428405762 -1614,1614,K109A,0.02844406,0.046878381,0.03504426,0.029736288,0.017570764,0.043498195,0.048005702000000004,0.008882418000000001,0.036429266,-0.01956826,0.113325022,0.011890379,0.05819814,-0.031857893,0.091330469,-0.009999934,0.045141462,1.132987694,2.327309098,-4.353227469,-3.785223808,-4.974219399,-3.858998016,-6.278419029,-2.869277092,-4.4666974,-0.971510338,-6.880957126617432,-9.404484748840332,-7.180239200592041,-10.126502990722656,-7.200829029083252 -1615,1615,K109C,-0.027875421,0.073119575,0.0016240470000000002,0.039279574,-0.977215953,0.059233019000000005,0.04944343599999999,-0.10519427699999999,0.192399601,0.024353376,0.121885773,0.041275955,-0.038027861,0.0040354,0.074523748,-0.623321397,-1.3311105090000002,0.8828937790000001,1.451681311,-9.029963824,-9.753609062,-9.405678879,-9.001555229,-9.783966545,-7.205009407,-7.470204852999999,-2.454464573,-11.268789291381836,-11.435128211975098,-11.703824996948242,-13.225128173828125,-12.040773391723633 -1616,1616,K109E,-0.000292405,-0.001584097,0.013331059,-0.013742216000000002,-0.046458354,0.026554888999999998,0.042322642,-0.042907451,0.098374751,-0.040287743,0.037119549,-0.015904589,0.042566707,-0.069310542,0.04182611,-0.067520377,-0.02539633,1.340688798,2.4032097169999997,-3.7992583019999997,-2.601505898,-4.471028015,-4.480221123,-4.301773735,-3.1417627410000004,-4.332568487,-0.688184265,-7.955620765686035,-9.471181869506836,-7.119736671447754,-10.111085891723633,-7.121349334716797 -1617,1617,K109D,-0.014672826000000002,0.011774978,0.0027994359999999998,-0.016769497,-0.042958069,0.057486722000000004,0.043002433,-0.072348085,0.15804675599999998,-0.036312283,0.059862238,-0.01140437,0.017003242,-0.081347592,0.047808598,-0.09108136800000001,0.005165231,1.3626647980000002,2.259569601,-5.181684586,-3.136458916,-6.395323715,-5.259214447,-5.50312394,-5.61430191,-4.741204381,-1.555315251,-9.542686462402344,-11.537115097045898,-8.663456916809082,-11.317708969116211,-9.418526649475098 -1618,1618,K109G,0.002672515,0.047687515,0.019483748999999998,0.0074065469999999994,-0.0064317540000000005,0.0232358,0.029711275,-0.024366246,0.200450605,-0.021930058,0.11730508699999999,0.033183047,0.00578445,-0.034426677999999995,0.049239772,-0.028513605,0.015650098,1.481553083,2.665887239,-6.023096526000001,-5.08488327,-7.091028641,-5.441892776,-6.82598082,-5.671697121,-5.566770764,-2.337747721,-9.914857864379883,-11.217655181884766,-8.633623123168945,-11.179197311401367,-8.832101821899414 -1619,1619,K109F,0.024535317999999997,0.09553667199999999,0.079844958,0.073698489,-0.125324548,0.018485131999999998,0.04040084,0.008669795,-0.061269657000000005,0.014932932,0.176140412,0.045900542,0.113789374,-0.038426149,0.185823127,-0.160404393,-0.09024470300000001,1.324858101,2.14707842,-9.482551186,-11.86960992,-9.504344254,-9.07549144,-9.866027016,-7.097283295,-6.876971451,-1.5404844640000002,-11.318516731262207,-12.565071105957031,-11.545842170715332,-12.502764701843262,-12.049095153808594 -1620,1620,K109I,-0.039742176000000004,-0.053011092,0.043483997999999996,-0.021389766,-0.063511355,0.020715605,-0.006954792,-0.07252956,-0.36848922700000003,-0.05407080000000001,-0.051951384,0.091192051,-0.0042240559999999995,-0.074264574,0.031485043,-0.082467058,-0.044555650999999995,1.4178042830000002,2.340412478,-8.714991187,-9.287385994,-7.74149324,-8.217804825,-8.864197014,-9.46407486,-7.24171599,-3.532216432,-9.075679779052734,-10.175071716308594,-10.123245239257812,-11.666812896728516,-9.013202667236328 -1621,1621,K109H,-0.078775275,0.009830945,0.01970605,-0.017491391999999998,-0.05099694,0.018876801999999998,-0.074524471,-0.083026079,0.018443486999999998,-0.010319856,0.029981745,0.032826065,0.006586034,-0.012552737,-0.022430047,-0.034888048,-0.06710583099999999,1.171423235,2.36905779,-4.7742416930000005,-5.712094467000001,-4.953259238999999,-4.6698836980000005,-5.596277359,-2.939693703,-6.139817371,-1.94328294,-8.684965133666992,-7.836639404296875,-8.221821784973145,-8.648771286010742,-7.625065803527832 -1622,1622,K109M,-0.006816332,0.046203492,0.002561437,0.055370333,0.041160179,0.015175306000000001,0.038773977,-0.05240664,0.080310751,-0.020278637,0.112685621,-0.0009823260000000002,0.006105199,-0.032131464,0.14287213,0.010067186,0.07225317099999999,1.201458267,2.6370695669999997,-6.4391431720000005,-7.202456757,-6.757499825,-6.974284988,-6.128202278,-5.133272011,-7.01634083,-2.212230898,-9.05161190032959,-9.552353858947754,-9.119351387023926,-9.932826042175293,-8.815807342529297 -1623,1623,K109L,0.024717412,0.026432294,0.037757097999999996,0.046900884000000004,0.011094306000000002,0.015152957,0.061901702999999995,-0.01246688,0.059906795,0.0050914359999999995,0.047773152,0.038330667,0.037183528,0.002928705,0.090873063,-0.002426671,0.024615282999999998,1.158967774,2.5137537709999997,-5.065708559,-6.16477417,-6.2161759110000006,-4.464871567,-4.271160713,-4.211560432,-5.100827861,-1.3224483040000001,-8.788331985473633,-9.083794593811035,-8.479034423828125,-9.03653335571289,-7.573487281799316 -1624,1624,K109N,-0.019115398999999998,0.043923962000000004,0.033537661,0.050502122999999996,0.031006255,0.003545671,-0.007555361,-0.030675437000000003,-0.020059794,0.026066452,0.061781471,0.08502998699999999,-0.017954666,0.018136731,0.082867514,0.060654988,0.0013575220000000001,1.2472596120000001,2.952494681,-3.295075883,-2.149512573,-3.837780579,-3.887907753,-3.3232231139999997,-3.2769553989999998,-4.851799407,-1.91274472,-6.99882698059082,-8.674395561218262,-7.069843292236328,-8.263505935668945,-7.386279106140137 -1625,1625,K109Q,-0.011806025,0.023379151,0.060186079,0.061298219,0.015313737,0.045651698,0.035043181,-0.05865523,-0.073786214,0.046121525999999996,0.000636775,0.125620494,-0.005248336,0.005176029,0.117420409,0.031025984,-0.000398511,1.3495148209999999,2.8391011280000003,-1.7707762480000002,-1.491281937,-1.660228012,-2.173121521,-2.147014755,-1.3822350159999999,-2.535952549,-0.890693142,-6.351046562194824,-6.637481212615967,-5.790600776672363,-6.675750732421875,-4.516477584838867 -1626,1626,K109P,-0.006093254,0.02762997,0.021596887000000002,0.004347282,-0.973440827,0.067834302,0.024208274,-0.036394782,0.15166666,-0.024876491,0.08013643,0.004595882,0.038597891,-0.046332934000000006,0.055027498,-0.714737675,-1.2321439779999999,0.780478639,1.4069428380000002,-5.760922615,-6.8338524629999995,-6.02622628,-3.940642632,-6.910540939,-5.093350761,-5.372931787000001,-1.8365425030000002,-9.494277000427246,-11.413122177124023,-8.788252830505371,-13.214049339294434,-9.427675247192383 -1627,1627,K109S,-0.00356124,0.015488962,0.026857679,0.021227856,-0.01347513,0.007251985,0.032232027,-0.039354507000000004,0.12458144,-0.055158248,0.086136172,0.044291240999999995,0.009424116,-0.039920473,0.082376184,-0.028478978,0.0015287179999999999,1.25549214,2.396280602,-5.521957959,-5.40689595,-5.322072952,-5.509878998,-6.807999535,-4.56294236,-5.937251974,-1.6363116919999998,-8.335914611816406,-9.466297149658203,-7.595916748046875,-9.753721237182617,-7.9916558265686035 -1628,1628,K109R,0.03040023,0.046499582000000005,0.034492993,0.030856777999999998,0.007215051,0.009392594,0.062332983,-0.0015325229999999998,0.121597005,-0.038441381000000004,0.131440544,0.023714845,0.04527114,-0.022369304,0.08408285900000001,-0.033042678,0.04747278,1.4118036330000001,2.5506220490000002,-3.1053936280000003,-3.7529663089999996,-2.538917099,-2.988654083,-3.9854639510000003,-2.2609666980000003,-3.743749663,-0.9750058140000001,-6.478871822357178,-5.2603912353515625,-6.729872703552246,-5.89479923248291,-5.337009906768799 -1629,1629,K109T,0.038970563,0.06631382200000001,0.05520607599999999,0.052106105,0.002104742,0.013535529,0.08414337,-0.006202245,0.229572444,-0.021937414,0.154565058,0.03030905,0.080103101,-0.002941022,0.10715323199999999,-0.019370109,0.023579592000000003,1.181000236,2.530186669,-3.641806458,-2.583330475,-4.192586929,-4.0333724669999995,-4.976899162,-2.422843254,-4.421138463,-1.577395446,-7.435205459594727,-8.570908546447754,-7.388933181762695,-9.5014009475708,-7.419007301330566 -1630,1630,K109W,-0.010106988,0.052725192000000004,0.04005632,0.021347414,-0.11899215,0.028891632999999996,0.014321028000000001,-0.034535002999999995,0.142850326,0.006723125,0.09872725800000001,0.055397750999999995,0.024714887999999997,-0.028193256,0.070888084,-0.122814947,-0.115169353,1.2476712840000002,2.168986241,-9.504720107,-11.28918531,-10.07206214,-8.715817863,-9.138697769,-8.307837447999999,-7.087690927000001,-3.3641366039999996,-13.269004821777344,-13.147740364074707,-11.443439483642578,-13.772186279296875,-12.240989685058594 -1631,1631,K109V,-0.001895956,0.009295376,-0.0042364759999999994,0.001333875,-0.035012295,0.020518336,0.03358644,-0.037378352000000004,0.020425816,-0.055035553,0.073626305,0.007891389,-0.01636434,-0.035711047999999995,0.038378797,-0.062937337,-0.007087253000000001,1.327578822,2.422303233,-7.798070059,-9.234369727999999,-7.187826645,-7.569894791,-8.599716835,-6.3985422970000005,-7.000823671,-2.7027640639999997,-8.818655967712402,-10.694924354553223,-9.6979398727417,-11.761346817016602,-8.741894721984863 -1632,1632,K109Y,0.004076891,0.053019665,0.02609488,0.033641295,-0.101598564,0.011192236000000001,0.038526223,-0.030372442000000003,0.19266036,0.001490611,0.10454871800000001,0.018088259,0.034101501,-0.008622444,0.075905033,-0.067302713,-0.135894415,1.2199872859999998,2.328097342,-9.082824135,-11.67648757,-9.34545668,-8.764673683,-9.667875549,-5.95962719,-6.58106454,-1.8902279709999998,-11.981985092163086,-12.065475463867188,-11.998311042785645,-12.285770416259766,-11.428718566894531 -1633,1633,H110A,0.038637755,0.077784625,0.034206373,0.030551256000000002,-0.180897312,0.047387519,0.011621886000000001,0.065653623,0.010695158,0.09208838300000001,0.063480866,0.052462227,0.015950518,0.067023073,-0.005920562,-0.143030748,-0.21876387600000002,1.319181323,2.2254431059999997,-5.844996631,-7.387093056,-6.263704712000001,-5.084287239,-4.557429405,-5.932468742,-5.835245925,-1.69919104,-9.815807342529297,-11.191858291625977,-11.194818496704102,-11.90320110321045,-9.062191009521484 -1634,1634,H110C,0.031304961,0.000502866,0.0014431560000000001,0.002518984,-0.942352686,0.095586062,0.035427066,0.027182856000000002,-0.181501802,-0.062912505,0.063918237,-0.036075143,0.038961454,-0.092512871,0.097550838,-0.642132943,-1.242572428,1.428927681,1.707311847,-9.454433798,-11.098486300000001,-10.53846781,-8.20671666,-8.391663086,-9.036835136,-8.398658036,-5.707223483,-11.070487976074219,-11.356734275817871,-12.404949188232422,-12.556571006774902,-10.842546463012695 -1635,1635,H110E,0.067938409,0.069692113,0.082693061,0.057591152,-1.050391483,0.099180611,0.09904100099999999,0.036835816,0.018173968999999998,0.00603821,0.133346015,-0.013630645,0.17901676600000002,-0.017055446000000002,0.13223774900000002,-0.9532632659999999,-1.1475197,0.868901074,1.3882805040000001,-8.832541965,-10.15199719,-11.00059943,-7.37324115,-7.174894814,-8.461977233999999,-6.625025449,-2.722010828,-13.089578628540039,-13.561023712158203,-12.09349250793457,-12.478426933288574,-10.009740829467773 -1636,1636,H110D,0.073783953,0.13292474099999999,0.127604283,-0.469381462,-1.824052084,0.060888529000000004,0.056869777999999996,0.090698128,-0.345003933,0.044416445,0.221433037,0.067032475,0.18817609100000002,-0.27143342,-0.667329504,-1.8563532530000002,-1.791750915,1.32213546,1.350662228,-7.923399594,-8.729996796,-7.145591476,-7.283502876,-6.985531204,-9.472375618,-6.902109617000001,-2.851297565,-12.517264366149902,-12.76999282836914,-12.117429733276367,-11.540494918823242,-10.236942291259766 -1637,1637,H110G,0.046511183,0.071084305,0.042653119,0.052788706,-0.224713885,0.11181844099999999,0.02718088,0.06584148599999999,-0.137006296,0.035292979,0.106875631,0.030255646,0.055050592,0.023714392999999997,0.08186301900000001,-0.203686384,-0.245741386,1.508372056,2.252694637,-8.531174968,-10.52473109,-8.708365738,-7.808646507000001,-6.832405388,-8.781726112000001,-6.802260489,-4.125594996,-12.302454948425293,-14.03125,-11.639971733093262,-12.081270217895508,-10.139562606811523 -1638,1638,H110F,0.005827308000000001,-0.014051913999999999,0.061629027999999995,0.003411133,-0.053775393,-0.027656737,0.025612084,-0.013957468999999998,-0.16891267399999998,0.11219097199999999,-0.140294799,0.052958847,0.070299209,0.020939256,-0.01411699,0.021442298,-0.128993083,1.139725805,2.466694997,-4.711570827,-6.490245811,-4.993813049,-4.356510452,-3.5856920469999998,-4.131592773,-5.222799118,-1.063678543,-10.153963088989258,-9.339414596557617,-9.651436805725098,-8.323968887329102,-7.845378875732422 -1639,1639,H110I,-0.18625944,-0.05413914400000001,-0.169448335,-0.391798994,-1.990195929,0.023401997,-0.198251957,-0.174266922,0.065170532,-0.043935765,-0.064342523,-0.09965131599999999,-0.239245353,-0.231138825,-0.552459162,-1.555323257,-2.4250686000000004,1.4447624609999998,1.4264729390000002,-9.154582873999999,-9.748728722000001,-9.221094566,-9.275327873,-8.635115891,-8.892647316,-7.132626362000001,-3.517522407,-11.697684288024902,-12.09049129486084,-12.381508827209473,-12.856196403503418,-9.417135238647461 -1640,1640,H110K,0.15775979199999998,0.117709009,0.064340507,0.10697723699999999,0.012441677,-0.0025155729999999997,0.117059201,0.198460382,0.25705605800000003,0.041950765999999994,0.193467251,-0.01833594,0.147016954,-0.013672115,0.22762658800000002,-0.081207512,0.106090865,1.316692716,2.348542741,-6.15234933,-8.230588623,-5.487371819,-5.883220177,-5.427245926,-5.733320107000001,-6.072108159,-1.827919626,-10.10135555267334,-10.615216255187988,-10.559226036071777,-10.093152046203613,-7.028043746948242 -1641,1641,H110M,-0.055114977,-0.012243677,0.005485667,-0.00033342,-0.156592771,0.085418282,-0.06679742799999999,-0.043432525,-0.110920727,-0.000301968,-0.024185385,-0.010924752,0.021896086000000002,-0.019750146,0.019083306,-0.1165173,-0.19666824100000002,1.23962028,2.164649125,-8.188103514,-8.968504379,-7.134278877000001,-9.57928717,-7.8454686129999995,-7.412978531,-6.188690228,-2.203635534,-11.673870086669922,-12.245438575744629,-12.158058166503906,-12.345703125,-9.848946571350098 -1642,1642,H110L,0.048633537000000004,0.037931989,-0.002580328,0.030381736,-0.418581883,0.105899845,0.063006011,0.034261063,-0.079971591,0.025331112000000003,0.050532865999999996,-0.013807924,0.008647268,-0.018326977,0.07909044900000001,-0.333150528,-0.504013238,0.9977921340000001,1.6206715740000002,-7.004101031,-7.95456192,-6.263857123999999,-7.620977005,-6.1663538739999995,-7.014755234,-4.835962873,-0.792689715,-10.458937644958496,-10.307121276855469,-9.564911842346191,-9.199746131896973,-7.668633460998535 -1643,1643,H110N,0.001891826,-0.015215195,-0.021520455,-0.005085763,-0.016681125,0.056325555,-0.043714407999999996,0.04749806,-0.19239377,-0.06441946700000001,0.033989077,-0.036860486,-0.006180423000000001,-0.069328729,0.059157203,-0.028601172999999997,-0.0047610759999999995,1.31205633,2.46737095,-4.1409125289999995,-4.916292992,-3.9408578189999997,-3.973261368,-4.265060349,-3.609090118,-4.3440403110000005,-1.43195963,-7.178073883056641,-8.451855659484863,-7.712548732757568,-7.158541202545166,-6.393736839294434 -1644,1644,H110Q,0.021155674,0.059326207,-0.023658292999999997,-0.012208962,-0.231536315,0.063621163,0.04409549,-0.001784143,-0.11776015199999999,0.056877652,0.061774761,-0.031228214,-0.016088371,0.040261915,-0.064679839,-0.18359223300000002,-0.279480396,1.2285872359999999,2.001724344,-5.553862802,-6.647646324,-6.199977646000001,-4.978148323,-4.475428024,-5.468113692999999,-6.221746767999999,-2.213554205,-9.494927406311035,-9.734639167785645,-8.881585121154785,-9.261486053466797,-7.084887504577637 -1645,1645,H110P,0.033783594,0.058611995,0.0068167,-1.489324481,-2.301066404,0.074725595,0.059368099,0.008199088,-0.115721575,0.032301478,0.08492251099999999,0.007755535,0.005877864,-1.318417957,-1.660231005,-2.184386165,-2.417746642,0.5102835579999999,0.70543257,-9.39150408,-10.94757689,-9.635793677999999,-8.409570442,-7.976939728,-9.987639664,-6.9953604060000005,-2.547429062,-10.904126167297363,-13.583003044128418,-11.95936393737793,-13.084583282470703,-11.547399520874023 -1646,1646,H110S,0.149701731,0.131534928,0.103573376,0.064524863,-0.160450531,0.07679719,0.173644923,0.125758539,-0.130378543,0.063867348,0.199202508,0.040630655,0.166516097,0.010896076999999999,0.118153649,-0.191646452,-0.12925461,1.275083748,2.043950382,-7.442917828,-7.801526009,-8.396411842000001,-6.106453781,-6.56011412,-8.350083389,-6.678400827000001,-2.84462119,-10.207405090332031,-11.31074047088623,-11.24231243133545,-11.168320655822754,-8.796594619750977 -1647,1647,H110R,0.057305195,0.066930269,0.036511361,0.055122012000000005,-0.059301023,0.027311383999999998,0.054205927,0.060404463,-0.061007277,0.038711062000000004,0.095149475,0.034448441,0.038574281,0.019603164,0.09064086,-0.030992706000000002,-0.08760933900000001,1.2360777040000002,2.567918366,-3.375171178,-4.200438255,-3.469648842,-3.3369304810000004,-2.489448105,-3.379390205,-3.4065854110000005,-0.685438714,-8.02170181274414,-6.3252410888671875,-7.216082572937012,-8.143925666809082,-6.216219902038574 -1648,1648,H110T,0.100636716,0.11055311699999999,0.043779389,0.10421038099999999,-1.55125933,0.056698258,0.111180129,0.09009330199999999,-0.27592301399999997,0.060139475,0.16096675900000001,0.020488538,0.067070239,0.07757552599999999,0.130845236,-1.544327873,-1.558190786,0.60515725,1.313752295,-7.573074097999999,-8.246716034,-7.85227388,-7.697088394,-6.809079787999999,-7.260212395,-6.061448112000001,-3.30187053,-10.133549690246582,-11.232946395874023,-11.01805305480957,-11.914053916931152,-9.288326263427734 -1649,1649,H110W,0.087682249,0.054165230999999994,0.010769338,0.048566727000000004,-0.560469723,0.11286315599999999,0.0827058,0.09265869800000001,-0.130283272,0.04293783,0.065392632,0.077789256,-0.056250580999999994,0.042308541,0.054824912999999996,-0.40491642299999997,-0.716023023,0.609118759,1.449400134,-8.208751024,-11.12367922,-10.12506767,-7.212851906,-5.426374099999999,-7.155782219,-5.23797326,-3.308831413,-11.317401885986328,-10.120437622070312,-11.373688697814941,-11.036407470703125,-9.500310897827148 -1650,1650,H110V,0.058491357,0.08129044099999999,-0.00890535,0.018520619,-1.7412102319999998,0.100334431,0.095954469,0.021028243999999998,-0.047490512,0.016437306999999998,0.146143575,0.009018255,-0.026828955,0.010183534000000001,0.026857702999999997,-1.592465065,-1.8899553980000001,0.46002635399999997,1.305268325,-7.610896207000001,-7.759206841,-7.096888725,-8.411404305,-7.633542915,-7.153438248,-5.849242852000001,-2.359017037,-11.03514289855957,-11.328266143798828,-12.0003023147583,-12.708916664123535,-8.48909854888916 -1651,1651,H110Y,0.114829691,0.177005297,0.175593952,0.045922594000000004,0.104755124,0.02413368,0.06548359599999999,0.164175785,0.052936075,0.066170598,0.287839995,0.12646296,0.22472494399999998,0.075071965,0.016773223,0.052340612,0.157169635,1.283942732,2.878264802,-3.3007122819999997,-2.744105621,-3.642023445,-3.458591728,-3.0268205339999996,-3.6320200810000003,-4.218799341,-1.0426746409999998,-9.18113899230957,-6.846669673919678,-7.699165344238281,-6.9838457107543945,-6.229677677154541 -1652,1652,L111A,-0.02653579,-0.035827894,-0.003869327,-0.057030278,-0.17892214899999997,-0.004677636,-0.018803564,-0.034268016,-0.046270399000000004,-0.03257593,-0.039079857,0.012577041,-0.020315694,-0.068047673,-0.046012883,-0.09770544099999999,-0.26013885600000003,1.49477802,2.415633588,-3.9082429339999996,-4.663923927,-2.7029652939999997,-3.877145226,-3.005191589,-5.291988632,-4.194999462,-0.51667604,-7.275467395782471,-12.914247512817383,-8.699459075927734,-9.028984069824219,-9.245518684387207 -1653,1653,L111C,-0.04349062,-0.014662399,-0.026231848,-0.070146843,-0.230763117,0.077583182,-0.029097032999999998,-0.057884207,-0.070120467,-0.039203341,0.009878544,-0.0067242330000000005,-0.045739462,-0.04734986,-0.092943826,-0.149381126,-0.312145108,1.487458285,2.284829967,-9.048746159,-9.831974197000001,-8.909032219,-9.233837776,-8.664613762,-8.604272842,-8.943109677999999,-5.3404849489999995,-9.485125541687012,-15.196895599365234,-11.785595893859863,-10.885214805603027,-12.578910827636719 -1654,1654,L111E,-0.095685793,-0.082071992,-0.05410163,-0.083557101,-1.001409632,0.005979231999999999,-0.121621496,-0.06975009,-0.112727408,0.0016258,-0.165769783,0.012544762,-0.120748021,-0.035115403999999996,-0.131998797,-0.7862436859999999,-1.216575578,0.866332785,1.4149141180000002,-6.939059985,-7.99704995,-7.194197472000001,-7.394805855,-6.224513908,-5.884732742000001,-6.668784054,-1.897208284,-11.040168762207031,-15.390022277832031,-12.982589721679688,-10.49587631225586,-11.261754989624023 -1655,1655,L111D,-0.059369451,-0.017220878999999998,-0.010196289,-0.007861108,-1.705468068,0.001457449,-0.078360172,-0.040378729,0.025089991000000002,-0.0019627860000000002,-0.032478972,0.031571559,-0.051964135999999994,0.043677494000000004,-0.05939971,-1.2211960370000001,-2.189740098,0.622015482,1.33147378,-8.097880161,-9.436693169,-9.480560822000001,-8.544797562000001,-6.805825386,-6.221523865,-6.328573276,-0.534537639,-11.715032577514648,-16.597103118896484,-14.185428619384766,-12.194765090942383,-12.364789962768555 -1656,1656,L111G,-0.049181958,-0.039091834,-0.010697775,-0.035929492,-1.338578008,0.042470537999999995,-0.04655093,-0.051812985,-0.038032887,-0.005902086,-0.072281581,0.019700956000000002,-0.041096505,0.006800786999999999,-0.07865977,-1.264576194,-1.4125798219999999,0.70107297,1.33468519,-6.916784602000001,-8.239035568,-3.908784462,-8.019172096,-6.301642997999999,-8.115287888,-6.61099249,-1.778660712,-11.092941284179688,-14.9099702835083,-11.694068908691406,-11.196168899536133,-12.312068939208984 -1657,1657,L111F,-0.020655987,-0.017356114,-0.032008436,-0.07482338599999999,-0.056213048,0.056454534,0.013239182,-0.054551155,0.09012177800000001,-0.063274707,0.028562478999999998,0.010269241,-0.074286112,-0.108692015,-0.040954756,-0.09916966199999999,-0.013256433,1.5153777019999999,2.418097152,-5.009586122,-6.010768897999999,-5.300861305,-4.618344093,-5.0832345430000005,-4.034721771,-6.234747921,-2.135161391,-9.173062324523926,-10.95015811920166,-10.11507511138916,-9.947731971740723,-9.488286018371582 -1658,1658,L111I,-0.02350057,0.033284014,-0.017627259,-0.000264236,0.051210423,0.008236486,-0.030142025,-0.016859115,-0.121272989,-0.046381926,0.112949953,0.027495439,-0.062749957,0.06545429,-0.065982762,0.018934282,0.083486563,1.142877423,2.7858118289999996,-2.310262315,-1.8449330290000001,-2.386923943,-2.913589623,-2.0323097,-2.373555283,-3.610687787,-0.765635732,-6.346916198730469,-6.846180438995361,-6.695001602172852,-4.852761745452881,-5.871694564819336 -1659,1659,L111H,-0.064360297,-0.010672718999999999,-0.022777067999999998,-0.028970195,-0.11959502699999999,0.03374217,-0.078189968,-0.050530625999999995,-0.059712108,0.012010477,-0.033355914,0.053295178,-0.09884931300000001,0.020466022,-0.07840641200000001,-0.071874645,-0.167315409,1.2290995340000002,2.361328104,-7.615979767000001,-9.163797417,-7.909092682000001,-5.97138414,-7.402978325,-7.6326462710000005,-7.546785667000001,-1.78749682,-11.6770658493042,-14.143254280090332,-13.728830337524414,-11.196680068969727,-11.911186218261719 -1660,1660,L111K,-0.027043373,-0.054481634,-0.052749002,-0.078842333,-0.445290177,0.029784212,-0.003139714,-0.050947031,0.007045488000000001,-0.112802616,0.003839348,-0.035494525,-0.070003478,-0.043189477000000004,-0.11449518800000001,-0.277948911,-0.6126314429999999,1.4406248590000001,2.005843982,-6.370346673999999,-7.557965462,-4.472382095,-6.801442451000001,-5.609434555,-7.410508804,-6.078971082000001,-1.179979916,-10.680832862854004,-12.78296184539795,-12.782654762268066,-9.797574996948242,-11.241227149963379 -1661,1661,L111M,-0.043207511,-0.064593793,-0.058739247,-0.11902195199999999,-0.008178508000000001,0.0073366130000000005,-0.008060951,-0.07835407,-0.169045771,-0.028430092,-0.100757493,0.013794641000000002,-0.131273135,-0.002540273,-0.23550363100000002,-0.035353794,0.018996779,1.267886367,2.607370612,-5.240131137,-5.354148499,-5.195412964,-5.347448067,-5.066250999,-5.237395157,-6.87807075,-3.4480986760000003,-7.367259502410889,-9.318087577819824,-8.277023315429688,-7.426589488983154,-7.193129539489746 -1662,1662,L111N,-0.13494976,0.001111975,-0.025067205,-0.029740506,-1.7939235080000002,-0.019385915,-0.156808964,-0.113090555,-0.010683278999999999,0.025540748,-0.023316799,0.044884775,-0.095019185,0.07620347599999999,-0.135684487,-1.56045107,-2.027395945,0.59848298,1.3126232740000001,-8.124309364,-9.73889315,-7.028220009,-8.740358978,-7.504422256000001,-7.6096524279999995,-7.664919737000001,-2.371944116,-10.749818801879883,-14.91486644744873,-13.622943878173828,-10.729310989379883,-10.697712898254395 -1663,1663,L111Q,-0.094078926,-0.029606527999999997,-0.0006122559999999999,-0.06544736599999999,-0.08332181,0.059973926,-0.087131956,-0.101025895,-0.128129025,-0.007006691999999999,-0.052206364000000005,0.051911042000000004,-0.053135552999999995,-0.014538768,-0.116355963,-0.10981490099999999,-0.056828718,1.3093393999999998,2.222427284,-5.303983983,-6.573063682999999,-4.757867134,-4.516465759,-4.7808577880000005,-5.89166555,-5.67076556,-2.105276155,-10.185306549072266,-13.129253387451172,-12.676983833312988,-8.62705135345459,-10.056422233581543 -1664,1664,L111P,-0.057375521,-0.0065282809999999995,-0.021040383,-0.033667302999999996,-1.124830808,0.063305069,-0.05090578,-0.063845261,-0.040539913999999996,-0.008809485,-0.004247076,0.020385643000000002,-0.062466409,-0.025640925,-0.04169368,-0.8737038359999999,-1.3759577790000002,0.708401941,1.37035961,-6.5658568189999995,-7.48830378,-6.641046417,-6.400317337000001,-5.336764175,-6.962852386000001,-5.629951077,0.211347068,-11.368429183959961,-12.735651016235352,-10.84927749633789,-13.449394226074219,-12.807561874389648 -1665,1665,L111S,-0.053143752999999995,-0.018670079,-0.05027729400000001,-0.042522476,-0.25549611699999997,0.023508763999999998,-0.063845992,-0.04244151400000001,0.014224073,-0.02266183,-0.014678328000000001,-0.017428465,-0.083126123,-0.014656799,-0.070388153,-0.22988010899999997,-0.281112125,1.45657963,2.113026454,-6.028996951,-7.864766106,-5.408120255,-6.1846288760000006,-5.436980957,-5.250488563999999,-6.322337131,-0.936089205,-10.220846176147461,-14.605741500854492,-12.08098316192627,-10.528843879699707,-10.738595008850098 -1666,1666,L111R,-0.063575711,-0.036546873,-0.007371007,-0.053460170999999994,-0.788257468,0.054496551,-0.074563499,-0.052587922,0.017769353,-0.005450356999999999,-0.067643389,0.005813658,-0.020555672,0.002620139,-0.10954048,-0.576171564,-1.0003433720000001,0.632759499,1.4063301419999998,-5.66368194,-6.512621895,-4.499097954,-4.408205269,-5.616918724,-7.281565857,-6.012748567,-1.3889517619999998,-9.796232223510742,-12.17156982421875,-12.066611289978027,-8.912565231323242,-11.265621185302734 -1667,1667,L111T,-0.01541583,-0.044761405,-0.04337692,-0.03898053,-0.055475814000000005,0.008589567,-0.01452311,-0.016308549,0.011815091000000002,-0.073700385,-0.015822423999999998,-0.046904819,-0.03984902,-0.048655585,-0.029305475,-0.086277376,-0.024674251,1.3526152059999998,2.29140379,-4.0918962919999995,-4.984808578,-3.4108252869999998,-5.029428543,-3.253249275,-3.7811697769999997,-5.008665478999999,-1.050372661,-7.856627941131592,-12.2904691696167,-9.845781326293945,-9.142858505249023,-8.969436645507812 -1668,1668,L111W,-0.0023387910000000002,-0.011565061000000001,-0.027921996,-0.04624976,-0.08093974,0.022875655,0.012230033000000001,-0.016907615,-0.059375203,-0.03076246,0.007632338000000001,0.0051328829999999995,-0.060976875,-0.043837929000000005,-0.048661591,-0.11147849300000001,-0.050400987,1.5345992169999998,2.41063141,-8.943880603,-9.99213443,-9.816200333,-8.691106972,-8.473055977000001,-7.746905303999999,-8.227982867,-3.7191765689999996,-12.720235824584961,-13.772612571716309,-13.675687789916992,-12.746543884277344,-13.558996200561523 -1669,1669,L111V,-0.00018323599999999998,-0.010792247,0.0070174519999999995,-0.010388135,0.03501739,-0.056564712,-0.03321218,0.032845709,-0.094185899,-0.030473835,0.008889341,-0.008275879,0.022310782999999997,-0.010045941999999999,-0.010730328,0.0018364429999999999,0.068198336,1.1861853999999998,2.528187983,-1.552259564,-1.181892738,-1.418170746,-2.101700302,-0.95222596,-2.107308075,-2.460434255,0.702979705,-4.076484680175781,-6.796041965484619,-3.810497283935547,-3.3096442222595215,-3.128432273864746 -1670,1670,L111Y,-0.059021773,-0.016906024,-0.004627352,-0.034095154,-0.079256332,0.011085748000000001,-0.063045356,-0.05499819,-0.17529472,-0.010781251,-0.023030797000000002,0.03847238,-0.047727083,0.032985232,-0.10117554,-0.022514778,-0.135997885,1.140691649,2.405539867,-8.267697539,-9.277981911,-9.192569191,-8.001496536,-7.56608017,-7.300359886,-7.74286341,-3.109384185,-11.969306945800781,-14.512250900268555,-13.248180389404297,-11.740161895751953,-12.0767822265625 -1671,1671,T112A,0.011455861999999999,0.042646225,0.004205864,0.036363413,0.040527258,0.045147429,0.016444668,0.006467055,0.058735864000000006,0.06313674,0.02215571,0.021308083,-0.012896355,0.032891312,0.039835514,0.037868888999999996,0.043185627000000004,1.085105223,2.64713552,1.405103749,1.576309456,1.367824799,1.6767867509999999,0.867921646,1.5366760940000002,-0.960019016,1.894238911,-1.9773536920547485,-1.7204999923706055,-2.064326763153076,-2.365372657775879,-2.388813018798828 -1672,1672,T112C,-0.079643134,0.031055802999999996,-0.044951537,-0.020494342,-0.224731163,0.080471446,-0.104899887,-0.054386381,0.089680668,0.049570069,0.012541536,0.010023436,-0.09992651,-0.007395281,-0.033593403,-0.22836411399999998,-0.221098212,1.493993453,2.143045545,-4.592858835,-4.582690986999999,-5.3120612110000005,-3.9851454160000004,-5.907271515,-3.1771250460000005,-6.69245672,-2.1463341330000003,-7.969801425933838,-9.271181106567383,-9.823250770568848,-7.642688274383545,-9.228418350219727 -1673,1673,T112E,0.02122863,0.074811056,0.072928275,0.082174505,0.028461722000000002,0.092016477,0.010184095,0.032273164,0.070287533,0.105308731,0.04431338,0.079731738,0.066124812,0.076083414,0.088265595,0.017743635,0.039179807999999997,1.144345991,2.8086535560000003,-0.9533887409999999,-0.6607883529999999,-1.725560165,0.362041061,-2.475657509,-0.26697873699999997,-3.981641353,1.271451842,-4.063136100769043,-5.541607856750488,-1.957281470298767,-3.904664993286133,-3.371729612350464 -1674,1674,T112D,-0.038839234,0.018815949,-0.034780396,-0.000195934,0.001599065,0.03837516,-0.032881226,-0.044797240999999995,-0.120618955,0.037716698,-8.48e-05,-0.021246805,-0.048313985999999996,0.0063731790000000005,-0.006765047,-0.0049474440000000005,0.008145574000000001,1.543610422,3.106887046,-0.498414029,-0.8029488220000001,-1.1673283840000002,0.809302933,-0.186737663,-1.1443582079999999,-2.772053685,2.1451237340000002,-3.906010627746582,-4.638532638549805,-2.1318435668945312,-4.282301425933838,-3.575444221496582 -1675,1675,T112G,0.026610681,0.056156316,0.05185028,0.042714632,0.068757914,0.029777355,0.012004666,0.041216696000000004,0.00193298,0.051880354000000004,0.060432278,0.08867423199999999,0.015026326999999999,0.036638906,0.048790357,0.027814554,0.109701273,1.203076918,2.833734906,-0.499880321,-1.3888083269999998,-0.622971489,1.310886536,-1.5368383330000002,-0.261669991,-3.49745091,2.762128844,-3.301178455352783,-3.237337112426758,-3.9958205223083496,-3.2447333335876465,-3.45890212059021 -1676,1676,T112F,0.041803513,0.04781826,0.027126255,0.027919667000000002,0.049081384000000006,-0.08405665400000001,-0.001915726,0.085522751,0.067282023,0.039853959,0.05578256,0.01785667,0.036395839,0.027365321,0.028474012000000003,-0.022342141,0.12050490800000001,1.301408296,2.6159409030000003,-6.73074155,-5.78285994,-7.770326294,-6.019188065,-9.100101624,-4.981231827,-6.360780882999999,-2.2176044569999998,-7.3667449951171875,-7.676007270812988,-9.220545768737793,-8.109618186950684,-7.810247898101807 -1677,1677,T112I,0.019470795,0.08200268299999999,0.042175594000000004,0.029017987999999998,0.084895434,0.037864818,0.054533882,-0.015592293,-0.12886903,0.107009108,0.056996257,0.072620428,0.01173076,0.050497642,0.007538334,0.061297064000000005,0.108493804,1.16819842,2.9379045169999998,-4.418763606000001,-4.290004082,-4.642508095,-3.401336723,-5.748713157999999,-4.011255974,-6.574473338,-2.1850472930000002,-5.2003703117370605,-5.662586212158203,-6.423040866851807,-6.77604866027832,-5.688236236572266 -1678,1678,T112H,-0.054934325,-0.011697365,0.005451869,0.039837585,0.012700158999999999,0.076252052,-0.050813362,-0.059055287000000005,-0.120820577,0.029746814,-0.053141544000000006,0.042293217,-0.031389479,0.053359641,0.026315527999999998,0.023295827999999998,0.0021044889999999998,1.142036181,2.7338256210000003,-4.191354694,-4.578929237,-5.161709877,-2.610330185,-5.435196312,-3.170607857,-5.05105806,-0.17606046,-6.193137168884277,-5.97476863861084,-5.718263149261475,-5.523420810699463,-5.472028732299805 -1679,1679,T112K,0.041602994,0.028859506,0.057573624000000004,0.07160876599999999,0.061175424000000006,0.057879865999999995,0.039882917999999996,0.04332307,-0.00885153,0.050966434000000005,0.006752578,0.053555052,0.061592195999999995,0.046076873,0.097140658,0.052379238,0.06997161,1.130137451,2.8466913889999996,-1.203565997,-1.1176535490000001,-2.1255835419999998,0.057271721,-2.341949005,-0.48991561100000003,-3.032705327,0.323976954,-3.5453763008117676,-3.6447792053222656,-3.249629020690918,-3.8474173545837402,-3.500251054763794 -1680,1680,T112M,0.035176819,0.040108987,0.068080856,0.066504614,0.008222842,0.020392238,0.026224226,0.04412941099999999,0.223313488,0.048346213,0.03187176,0.012953793,0.12320791800000001,0.035132327000000005,0.09787689999999999,0.006412079,0.010033605,1.189559922,2.647125377,-5.120463095,-5.235074265,-5.831234932,-4.251454605,-6.573985167999999,-3.710566505,-6.914458118,-2.699482966,-6.741042137145996,-6.045252323150635,-7.2317352294921875,-6.925660133361816,-6.813513278961182 -1681,1681,T112L,-0.020201141000000002,0.014839311,0.025108456,0.051326414,0.012445887,0.026128879,0.0030726290000000003,-0.043474911,0.11486556099999999,0.037082585,-0.007403964,0.05513705,-0.0049201390000000005,0.037678939,0.064973888,0.011421126,0.013470646999999999,1.085105223,2.64713552,-5.219605275,-4.919007835,-5.966357062999999,-3.7938082580000003,-6.94035154,-4.478501678,-6.231496266000001,-1.995860259,-5.529148101806641,-5.3763556480407715,-6.276020050048828,-6.253199100494385,-5.723992347717285 -1682,1682,T112N,-0.009063640999999999,0.04443331,0.041230197999999996,0.06422636799999999,0.049527478,0.044450194000000005,0.00014086,-0.018268141,-0.16363113599999998,0.057433773,0.031432847,0.037887996,0.044572399000000006,0.048151461,0.080301275,-0.023630287000000003,0.12268524300000001,1.111723942,2.5148718580000002,-1.343508752,-1.7315645290000001,-1.848088219,-0.824544594,-1.3734450759999999,-0.939901344,-3.486347711,0.987854975,-4.295312404632568,-3.3782284259796143,-4.1498870849609375,-4.263505935668945,-3.5706748962402344 -1683,1683,T112Q,-0.029575915,-0.04801441099999999,-0.076122429,0.005136482,-0.051817832,0.038793821,-0.021353836,-0.037797994,-0.04262593,-0.045223096,-0.050805725,-0.024569542000000003,-0.127675315,-0.014183298,0.024456262000000003,-0.045104423,-0.05853124,1.183851575,2.389461889,-2.8750772660000004,-2.742340439,-3.5551237789999997,-1.441348289,-5.0015898210000005,-1.6349840009999999,-4.2877325619999995,0.064901418,-5.152772903442383,-5.172167778015137,-4.322768211364746,-4.511880874633789,-4.352182388305664 -1684,1684,T112P,0.010092697,0.02156935,0.02324934,0.038241332999999995,-0.018968098,0.025197176,0.018488552,0.0016968410000000001,0.037723779,0.067618586,-0.024479886,0.049680034000000005,-0.0031813540000000004,0.030507377999999998,0.045975287000000004,0.004426022,-0.042362217,1.671448915,3.643209181,-2.300674808,-2.103926163,-1.792808975,-1.673031273,-5.184353722,-0.749253906,-3.729280301,1.476461483,-5.435369968414307,-8.404125213623047,-2.780378818511963,-6.589854717254639,-5.565298557281494 -1685,1685,T112S,0.01785622,0.012895163999999999,0.004823326,0.022131401000000002,0.018286818,0.021466087000000002,0.025060455,0.010651984,0.020512163,0.005982124,0.019808203,-0.003847701,0.013494353,0.005371847,0.038890955,-0.010130763000000001,0.046704398,1.237023233,2.517427644,-0.600694351,-0.41161332700000003,-0.199223183,-0.36838012700000006,-2.090945038,0.066689919,-3.474092637,0.567603443,-3.7426562309265137,-3.5780434608459473,-3.2461414337158203,-3.20190691947937,-3.495479106903076 -1686,1686,T112R,0.008951165,0.019459038999999997,0.029985337999999997,0.007776676,0.019411118,0.041464363,0.019223758,-0.001321428,0.050982377999999995,0.008553233,0.030364845,0.016862861,0.043107814,0.0016668129999999998,0.013886539,-0.027450181,0.066272416,1.1842911329999999,2.48731783,-2.920324733,-3.239659004,-3.224276955,-1.605931664,-4.358470886,-2.173285156,-4.192094414,0.000245234,-4.477490425109863,-5.259012699127197,-5.323629856109619,-4.93265438079834,-5.242467403411865 -1687,1687,T112W,-0.010893508,0.09226162800000001,0.063152755,0.072421922,0.006492854,0.020733544,-0.04275198,0.020964964,0.10157989099999999,0.147517274,0.037005981,0.085212865,0.041092644,0.10825706199999999,0.036586782000000005,0.02663463,-0.013648923,1.1102709990000001,2.803064708,-6.791883339,-6.659152572999999,-7.382258705,-5.6984283520000005,-8.972465775,-5.24711129,-7.24112777,-3.239852511,-9.77730655670166,-10.872329711914062,-11.196991920471191,-9.844764709472656,-9.850252151489258 -1688,1688,T112V,0.034623584,0.036818457,0.043372126,0.050460389,0.000436853,0.031395998,0.027551501000000003,0.041695666,0.05420835,0.071188232,0.002448681,0.078886421,0.007857831,0.035200922,0.065719856,-0.012663352,0.013537057,1.09141726,2.505512625,-1.9384017169999999,-1.936430649,-1.718351135,-1.6613186569999998,-2.904645248,-1.471262894,-4.61998564,-0.49938643200000005,-3.4809350967407227,-4.856313228607178,-5.497801780700684,-5.503117084503174,-4.663525104522705 -1689,1689,T112Y,-0.042348475,0.01752965,0.027047939,0.008257396,0.054425557,0.035622799,-0.081096972,-0.0035999770000000003,-0.0248642,0.059336235999999994,-0.024276936000000002,0.101613613,-0.047517736,0.064787049,-0.048272257,0.07249087,0.036360243,1.087675146,2.722527363,-6.2895237260000005,-5.672615829,-8.590038094,-5.148101097,-8.00239341,-4.0344702,-5.997148011,-1.39790749,-8.297810554504395,-8.555704116821289,-7.559022426605225,-8.379769325256348,-7.51851749420166 -1690,1690,D113A,-0.015131512,-0.095492424,-0.061248224000000004,-0.062972207,-0.06605382,-0.001297056,-0.026328939,-0.003934084,-0.421350768,-0.052407105,-0.138577742,-0.11328061800000001,-0.009215829,-0.032594212000000004,-0.093350202,-0.08546155400000001,-0.046646085,1.369038687,2.358196104,-4.2948486830000006,-4.809648605,-3.426271416,-4.006963928,-4.047490753,-5.183868713,-4.894475094,-0.06534175099999999,-5.660488128662109,-7.335436820983887,-8.307670593261719,-5.624637603759766,-6.875284194946289 -1691,1691,D113C,0.079122188,-0.053242532,-0.005413694,-0.044918278,-0.304002288,0.049325737,0.049676465,0.10856791,-0.39391251899999996,-0.070931171,-0.035553892000000004,-0.022601589,0.011774202,0.000105953,-0.089942509,-0.252564429,-0.35544014700000004,1.45712359,2.077991044,-9.300791753,-10.08878091,-8.12403804,-9.510665367,-9.865063843,-8.915410599,-8.93442439,-4.811168197,-9.47187328338623,-13.961974143981934,-11.791959762573242,-10.981765747070312,-13.655525207519531 -1692,1692,D113E,0.07024436,-0.033817562,-0.004989163,0.072579605,-0.005727654,0.025004009,0.139482681,0.0010060380000000001,-0.33321467899999996,-0.012064511000000002,-0.055570612,-0.075085944,0.065107619,0.053311881,0.091847328,-0.016031727,0.004576419,0.92629403,2.330417922,-1.364215793,-1.309781219,-1.366298882,-1.7381445469999999,-1.390731384,-1.016122932,-4.054731454,-0.247443031,-4.125690937042236,-6.785579681396484,-6.104005813598633,-5.100477695465088,-5.002570629119873 -1693,1693,D113G,-0.00845206,-0.131759496,-0.024608395,-0.016542548,-0.060906319,0.007929273,-0.031408464,0.014504345,-0.17236338699999998,-0.09359898400000001,-0.169920008,-0.10820284,0.058986051,-0.006475514,-0.026609581,-0.07821117400000001,-0.043601463,1.5413732580000001,2.49883553,-3.552532123,-3.214412148,-3.081349655,-3.4376115339999997,-5.496100082000001,-2.533187195,-5.7621087,1.177608532,-6.908182144165039,-8.314512252807617,-8.80083179473877,-7.565947532653809,-7.569779396057129 -1694,1694,D113F,0.013360006,-0.054449080999999996,-0.011758665,-0.002033386,-0.231182605,0.057668167,0.0014014029999999999,0.025318609,-0.283996656,-0.049593115,-0.059305047,-0.068288553,0.044771223,0.00157129,-0.005638061999999999,-0.267187637,-0.195177572,1.587489219,2.15923086,-9.803046328999999,-10.62046109,-7.563960442000001,-10.21429469,-11.85833366,-8.758181763,-8.790789574,-4.549415499,-9.376947402954102,-12.163093566894531,-12.494723320007324,-10.85705280303955,-11.245241165161133 -1695,1695,D113I,0.018361401,-0.055953496,0.003130716,0.021720153,-0.10136269199999999,0.035900992,0.018729766999999998,0.017993033999999998,-0.24778448399999997,-0.021077092999999998,-0.090829898,-0.066688149,0.07294958,0.026251833999999998,0.017188472,-0.128638001,-0.07408738200000001,1.386680422,2.2677355,-7.996512762,-9.105486588,-7.262091255,-7.759926865,-9.577324562000001,-6.277734542999999,-7.19297863,-2.1392693990000002,-6.507327079772949,-10.799064636230469,-10.789501190185547,-8.431900024414062,-9.159683227539062 -1696,1696,D113H,0.053154368,-0.097064427,-0.042392569000000005,-0.04771351099999999,-0.034760101,-0.027257313,0.013883598,0.09242513699999999,-0.252181428,-0.118028075,-0.076100778,-0.11321584400000001,0.028430706,-0.04515751,-0.050269510999999996,-0.085004955,0.015484753,1.36102041,2.314229171,-6.383333542000001,-7.31452832,-4.285401787,-6.772558311,-6.881367477,-6.662811812999999,-6.716489619,-1.8506309269999999,-7.165536880493164,-9.786623001098633,-8.485597610473633,-8.824005126953125,-8.91202449798584 -1697,1697,D113K,-0.023584661,-0.040841142999999996,-0.031843672,0.011931752,-0.042644241,0.015565672,-0.015373181999999999,-0.03179614,-0.019595556,-0.0036212970000000003,-0.078060988,-0.048979246,-0.014708097,0.031454282,-0.007590778,-0.033583311,-0.051705170999999994,1.3330098540000002,2.637029907,-3.780527765,-4.191460281,-3.8623471830000002,-4.40760453,-4.224083595,-2.217143234,-3.9857646860000004,-0.200880578,-5.565959930419922,-8.629918098449707,-9.257658004760742,-8.356735229492188,-7.928889751434326 -1698,1698,D113M,0.021792613,-0.121371565,-0.036394794,-0.03859152,-0.11808895400000001,-0.022514115,0.043920485999999995,-0.000335261,-0.012879528000000001,-0.09646205599999999,-0.146281073,-0.102279872,0.029490284,-0.065611123,-0.011571917,-0.201049046,-0.035128861000000004,1.432427684,2.111935461,-8.529227145,-9.488900635,-7.537936844,-8.632344887,-10.36845863,-6.618494728,-8.063207869,-3.587826783,-8.034998893737793,-10.647348403930664,-11.57730484008789,-9.36726188659668,-10.533252716064453 -1699,1699,D113L,0.001230983,-0.082658381,-0.04663140599999999,-0.023582636,-0.187793488,0.041656433,-0.003536653,0.005998619,-0.305185955,-0.058608405,-0.10670835599999999,-0.105004095,0.011741284,0.025109294,-0.072274565,-0.212746322,-0.162840654,1.204637967,1.966333505,-7.675806174,-8.944348793,-6.529307387999999,-7.8540263370000005,-9.80164724,-5.249701111,-7.382634317000001,-1.929697468,-7.012031078338623,-10.715934753417969,-10.908197402954102,-9.218182563781738,-9.304204940795898 -1700,1700,D113N,-0.003289525,-0.10198763599999999,-0.08778081300000001,-0.021207765,-0.052588139000000006,0.023045961,-0.017137178,0.010558128,-0.33321467899999996,-0.0445324,-0.15944287199999999,-0.12264250199999999,-0.052919123,0.016727427,-0.059142957,-0.058298314000000004,-0.046877962999999995,1.310227454,2.37781668,-3.901777501,-4.109251228,-2.600105591,-3.7807996060000004,-5.20781601,-3.81091507,-4.942077351,-0.9343369140000001,-5.018279075622559,-7.1179304122924805,-7.746557235717773,-6.151082515716553,-5.876589298248291 -1701,1701,D113Q,-0.006251139,-0.082461597,-0.043712282000000005,-0.026026505,-0.011883728999999999,0.002028102,-0.046422335,0.033920057,-0.36185986,-0.06012322,-0.104799973,-0.091252154,0.003827591,-0.014747831000000001,-0.037305178,-0.04847831,0.024710852999999998,1.427294333,2.456213609,-4.271402892,-4.889651871,-2.603302948,-4.962453979,-5.307768578,-3.593837082,-4.501103549,-0.56071467,-5.402194023132324,-8.626840591430664,-8.58671760559082,-7.759805202484131,-7.576106548309326 -1702,1702,D113P,0.019705121000000003,-0.051368187,-0.034524265,-0.030892901,-0.731114151,0.047504792000000004,-0.006139037,0.045549279000000005,-0.313745767,-0.046834407,-0.055901967000000004,-0.09445363400000001,0.025405105,-0.005969815,-0.055815987000000004,-0.644509979,-0.817718323,0.8352955559999999,1.442378991,-3.516033904,-3.202469048,-2.8431221239999998,-4.857700599999999,-3.3954136810000004,-3.2814640660000003,-4.508889684,-0.6217835939999999,-7.39491081237793,-9.686293601989746,-9.436873435974121,-7.526558876037598,-7.793120384216309 -1703,1703,D113S,0.011476431,-0.061166171,-0.043993410999999996,-0.021342664,-0.023461345,-0.007596613,0.008574701,0.01437816,-0.245600265,-0.019292353,-0.103039989,-0.091465263,0.003478442,0.014786461,-0.057471789,-0.032472556,-0.014450133,1.262234571,2.455472153,-4.087348668,-5.014725502,-3.093674866,-4.142994453,-3.297485245,-4.887863274,-5.172966389,-0.12313697800000001,-4.792503356933594,-7.917144298553467,-8.1932954788208,-6.0297956466674805,-6.723091125488281 -1704,1704,D113R,-0.002822522,-0.11708718300000001,-0.06491939099999999,-0.049748510999999995,-0.084542119,0.007624429,-0.040613292999999995,0.03496825,-0.28310488100000003,-0.052610377,-0.18156398899999998,-0.110848504,-0.018990277,-0.017622124,-0.081874897,-0.08746409699999999,-0.081620141,1.36733654,2.341892996,-5.511529041,-6.578319327999999,-3.334143402,-6.357819222000001,-6.250551086000001,-5.036812164,-5.879213936,-0.49368908799999994,-7.04256534576416,-10.141040802001953,-10.097177505493164,-9.725292205810547,-9.588067054748535 -1705,1705,D113T,0.037015457,-0.037334526,-0.015502806000000001,-0.00968365,0.022648909,0.000256886,0.009401691,0.064629222,-0.272393442,-0.023957035,-0.050712017000000005,-0.069014374,0.038008762,0.009798003000000001,-0.029165302,-0.008542009,0.05383982599999999,1.2700313540000001,2.57458469,-3.6450846689999996,-3.959183289,-3.7504104689999997,-4.157081734,-3.0630694660000004,-3.295678391,-3.7098041989999997,0.642943959,-2.100834369659424,-6.211095809936523,-7.67519474029541,-4.30061674118042,-5.9193949699401855 -1706,1706,D113W,0.023645436000000002,-0.10093603300000001,-0.06457817,-0.046143992,-0.320755549,0.062341886,-0.013554651000000001,0.060845522,-0.208275942,-0.073428917,-0.128443149,-0.126736601,-0.002419738,-0.069918535,-0.022369447999999997,-0.328800126,-0.312710972,1.536014856,2.037876761,-9.657498454,-10.60896717,-6.868633202000001,-10.16631997,-11.59500535,-9.048566582000001,-8.826552328,-4.828149529,-11.66814136505127,-14.486133575439453,-14.159231185913086,-12.181158065795898,-12.846488952636719 -1707,1707,D113V,-0.041728481,-0.133429698,-0.030321518,-0.08259573,-0.086303752,0.087188424,-0.062374043,-0.021082919,-0.7011914640000001,-0.096349271,-0.17051012399999999,-0.075398084,0.014755049,-0.016954192,-0.148237267,-0.19391603,0.021308526,1.576861764,2.272458472,-7.041252718,-7.596784927000001,-6.49940107,-7.158358871,-8.094346763999999,-5.857371956000001,-6.436067333,-0.416098024,-5.40736198425293,-9.355820655822754,-10.232208251953125,-7.345155239105225,-8.650993347167969 -1708,1708,D113Y,-0.00024946,-0.077922253,0.015943823,0.015987678999999998,-0.103097588,0.010656644,-0.022457045,0.021958125,-0.362178375,-0.002009696,-0.15383480900000002,-0.024881884,0.056769529000000006,0.072073572,-0.040098215,-0.08404550400000001,-0.122149671,1.173055706,2.275185432,-9.596172444,-10.75324971,-7.775384155,-9.815136833,-11.01723132,-8.619860199,-8.349510638,-4.268056883,-9.484880447387695,-11.502708435058594,-11.558370590209961,-10.400677680969238,-10.499283790588379 -1709,1709,G114A,-0.052258945999999994,0.017891372,-0.056769734,-0.167600109,-1.768156619,-0.043331769000000006,-0.052199485,-0.052318406,0.018356638999999998,-0.014443755,0.050226498,-0.022364987000000003,-0.09117448,-0.029074517,-0.30612570100000003,-1.770387729,-1.7659255090000001,0.705964267,1.309951274,-3.5990383269999997,-3.189959175,-2.807847427,-3.8692616039999996,-4.346995987,-3.781127441,-5.396161454,-1.677790505,-9.775917053222656,-9.382033348083496,-7.476126670837402,-9.385293006896973,-9.841675758361816 -1710,1710,G114C,-0.01753952,-0.012402567,-0.040880867,-1.1962679920000001,-1.693246199,-0.009382937,-0.007320245,-0.027758795,0.047249574,-0.071299301,0.046494167,0.014926887,-0.09668862,-0.917624222,-1.474911761,-1.9485477269999998,-1.43794467,2.215907864,1.586400324,-9.824396623,-9.722391685,-8.862535187,-10.44423263,-11.15914683,-8.933676788,-9.920189241000001,-6.480357687000001,-13.550725936889648,-13.28802490234375,-11.920980453491211,-11.511385917663574,-14.037820816040039 -1711,1711,G114E,-0.081181612,-0.078714079,-0.10992716400000001,-1.51613864,-2.497687707,-0.036786754,-0.036290341000000004,-0.126072882,0.098856889,-0.062191986,-0.095236171,-0.085214153,-0.134640174,-1.4090941380000002,-1.6231831419999998,-2.101663324,-2.8937120889999997,0.81416984,0.720916986,-4.581427092,-3.2144325869999997,-4.154622986000001,-5.698572716,-5.564590851,-4.274916321,-6.04106102,-1.3588487480000002,-10.015427589416504,-11.781484603881836,-8.616607666015625,-9.21438980102539,-10.924013137817383 -1712,1712,G114D,-0.017586551000000002,-0.012473668,0.067514041,-0.9091403440000001,-1.988670582,-0.059566247999999995,-0.034223662,-0.000949439,0.05349485599999999,-0.037151542,0.012204206,0.052720882000000004,0.0823072,-0.836929585,-0.981351103,-1.9822874469999998,-1.995053716,2.03843816,1.4866191380000002,-6.461937589,-5.942688277999999,-4.596543701,-9.465972359,-6.397940032999999,-5.906543571,-4.948080191,-1.998619221,-9.190962791442871,-11.116623878479004,-8.572309494018555,-8.31689739227295,-9.942947387695312 -1713,1713,G114F,-0.010803281999999999,-0.0013015589999999999,0.042601344000000006,-0.21276210199999998,-1.7025912230000002,-0.022620475,0.001423519,-0.023030083,0.07810758799999999,-0.066307588,0.063704471,0.019168739,0.06603394900000001,-0.051352128,-0.374172075,-1.479285674,-1.925896772,0.71528473,1.323577597,-10.51306375,-8.568481827000001,-10.28085043,-11.22390545,-12.79444001,-9.697641022,-8.245593846,-4.852211453,-13.75450325012207,-14.731160163879395,-13.126409530639648,-13.13284683227539,-14.5326566696167 -1714,1714,G114I,0.029938626,-0.003227213,-0.884318388,-2.0159821780000002,-2.694101807,-0.066959387,0.05657081,0.003306442,-0.119240834,-0.035717282999999996,0.029262857000000003,-0.745701877,-1.022934899,-1.64153018,-2.390434175,-2.5723385309999998,-2.8158650819999997,2.305264804,1.158789879,-8.525697266,-9.164081001,-8.069800964,-8.872663719,-9.044659287,-7.477281357000001,-8.444392314,-3.175788416,-14.746601104736328,-14.6455717086792,-12.288009643554688,-14.304346084594727,-14.114082336425781 -1715,1715,G114H,-0.062959066,-0.010459794,-0.016035178,-0.113281159,-1.947167109,-0.019273881,-0.024229606,-0.101688526,-0.11201479199999999,-0.010647865,-0.010271721999999999,-0.0068510409999999996,-0.025219315,-0.001212889,-0.225349429,-1.735283212,-2.159051006,0.750001987,1.311879328,-7.9079853270000005,-8.842045929,-8.006818932,-8.539644455,-7.992439667,-6.158977654,-7.143346854,-3.157490128,-11.932491302490234,-13.10197639465332,-11.051671028137207,-11.344215393066406,-13.397453308105469 -1716,1716,G114K,-0.0027364940000000003,-0.01086061,-0.050661106,-0.523086564,-1.4954849540000001,0.027439099999999998,-0.010034594,0.004561606,-0.121603276,-0.07831109900000001,0.05658988,-0.067371113,-0.033951099,-0.418326376,-0.6278467520000001,-2.048104732,-0.942865175,1.586200202,1.3555022719999998,-5.790717247000001,-4.818640686,-5.259508583,-7.473128418,-6.6610644070000005,-4.741244141,-6.673126292,-1.832793388,-11.258065223693848,-11.90287971496582,-10.210725784301758,-11.835123062133789,-12.650999069213867 -1717,1717,G114M,0.084114106,0.00922786,0.052482184,-1.128752379,-2.691067714,-0.055143399999999995,0.137125335,0.031102877,-0.063919886,-0.065867797,0.084323516,0.015414575,0.08954979199999999,-0.9141623109999999,-1.3433424459999999,-2.710272088,-2.671863339,0.7489601309999999,0.764557625,-9.253168694,-9.247984215,-8.733091805,-9.696616745,-10.34618143,-8.241969276,-8.345065635,-4.536344134,-13.194442749023438,-14.56206226348877,-12.691166877746582,-13.81283950805664,-14.276888847351074 -1718,1718,G114L,-0.050435,-0.062348978,-0.029288896000000002,-1.528448965,-2.1345131040000003,-0.011980735,-0.015110489,-0.085759511,-0.045746262999999995,-0.06267444,-0.062023515999999994,-0.017565782,-0.041012009,-1.24095101,-1.8159469190000002,-2.411652614,-1.857373594,0.912563893,0.749804708,-8.105803751,-7.334414902000001,-7.2620929489999995,-8.832146729,-9.777332535,-7.323031639,-7.795384577999999,-2.282779556,-13.289850234985352,-13.71596622467041,-11.531896591186523,-13.372222900390625,-13.547355651855469 -1719,1719,G114N,-0.057363309,0.032821027999999995,0.000379228,-0.12269792,-1.9791036180000001,-0.011775207,-0.059416271,-0.055310345999999996,-0.015561775,0.033706608,0.031935447,0.017237217,-0.016478762,0.000132755,-0.245528594,-1.865174048,-2.093033188,0.6700260170000001,1.302175855,-7.059820638,-7.249414291,-6.0157404329999995,-9.91010611,-6.652781822000001,-5.471060532,-6.587049112000001,-1.966976726,-10.524114608764648,-11.493675231933594,-9.990713119506836,-9.67130184173584,-11.116432189941406 -1720,1720,G114Q,-0.045663144,0.0018496779999999998,-0.004160515,-1.274182827,-2.111681837,-0.025283927,-0.03021725,-0.061109038,-0.080086842,-0.004895248,0.008594604,0.007220096,-0.015541125,-1.134590635,-1.4137750180000002,-2.354194526,-1.8691691480000001,0.7737229170000001,0.74414627,-4.872438417,-4.122978462,-4.391773872,-5.883182365,-5.946572395,-4.01768499,-5.373599185,-2.167280382,-11.506937026977539,-12.249184608459473,-10.182209968566895,-11.172260284423828,-12.548324584960938 -1721,1721,G114P,-0.046022219,0.004069263,0.001909876,-1.3924653269999998,-2.048173868,-0.032586097,-0.043314727000000004,-0.04872971,-0.081993107,-0.010364735,0.01850326,0.003494888,0.000324863,-1.1267285009999999,-1.6582021519999999,-2.251298384,-1.845049351,0.8045882790000001,0.7461577159999999,-6.513716069,-8.119616501,-4.904628983,-7.882971931,-7.314987122000001,-4.3463758089999995,-6.4227165170000005,-2.266757889,-14.671475410461426,-14.091596603393555,-9.87282943725586,-13.465154647827148,-12.827207565307617 -1722,1722,G114S,0.020665426,0.010883869,0.009627581999999999,-0.062394297,-1.6983153000000002,-0.039958661,0.029923098999999998,0.011407753,-0.020543218000000002,-0.055081258,0.076848995,-0.019789645,0.039044809,-0.045237844000000006,-0.079550749,-1.733286452,-1.6633441469999999,0.8505544559999999,1.316947228,-5.314125014,-5.613813545,-4.482084282,-5.569885017000001,-5.866602806,-5.038239418,-5.312657173,-1.6121347430000001,-10.065230369567871,-9.635804176330566,-7.951041221618652,-8.834749221801758,-9.204462051391602 -1723,1723,G114R,-0.019843435,-0.006754785,-0.111614522,-1.544478784,-2.508646797,-0.033358566,0.005624947,-0.045311816,-0.12875509400000001,-0.011019128999999999,-0.00249044,-0.09722925199999999,-0.125999791,-1.3260567559999998,-1.762900811,-2.351840621,-2.6654529719999998,1.008379288,0.7548773809999999,-5.330821971000001,-3.8295086589999996,-6.295630104,-6.086318596,-5.552007248,-4.890645248,-6.531094649,-1.75195871,-11.103999137878418,-10.97533130645752,-9.463624954223633,-11.051758766174316,-11.63258171081543 -1724,1724,G114T,0.008407985,-0.023327467999999997,0.016535778,-1.2128749909999998,-1.887151206,-0.032864213999999996,-0.016962848,0.033778817,-0.0017341820000000001,-0.061125349,0.014470413,0.012470193999999999,0.020601361999999998,-0.962133661,-1.46361632,-2.084827539,-1.689474872,2.133368712,1.4762068130000001,-5.66976028,-5.413350845,-5.298682503,-5.9479913479999995,-6.348618652000001,-5.340158051,-6.099292824,-0.9458575859999999,-12.141077995300293,-12.110917091369629,-9.769248008728027,-11.164144515991211,-11.698952674865723 -1725,1725,G114W,-0.049827294,-0.029305054,-0.019590765,-1.155348911,-1.979103619,-0.029014825,-0.087860786,-0.011793801999999999,-0.194742737,0.02102922,-0.079639328,-0.047566711,0.008385182,-0.8314212540000001,-1.4792765669999999,-1.849379781,-2.1088274559999998,2.252496589,1.6488633940000001,-10.825883099999999,-10.22910381,-9.719610458,-11.99006111,-12.54962327,-9.641016853,-9.526568028,-6.212724442000001,-13.291120529174805,-13.894590377807617,-12.58607292175293,-12.488858222961426,-13.898398399353027 -1726,1726,G114V,-0.033008155,-0.019527878000000002,-0.205982146,-1.471611362,-2.478018652,0.0038431409999999996,0.020184786,-0.08620109599999999,0.010862417,-0.043885529000000006,0.004829773,-0.185896998,-0.226067293,-1.468541909,-1.474680815,-2.73141449,-2.2246228130000003,1.21290972,0.7688574990000001,-6.695513715,-7.410922089,-6.246939262000001,-7.145272713,-6.629886696,-6.044547812999999,-6.984001283,-2.2000305,-13.31048583984375,-13.244034767150879,-10.63135051727295,-12.530715942382812,-12.582393646240234 -1727,1727,G114Y,-0.044944248,0.027786257999999998,-0.027859482999999997,-0.243021703,-1.924038428,-0.00392352,-0.029596638999999998,-0.060291856,-0.030569203,0.027105498,0.028467017999999997,-0.006352711,-0.049366255,-0.062284167,-0.423759239,-2.015920049,-1.832156806,0.812527606,1.298921062,-9.847987239,-8.644797394,-10.15470536,-10.35064492,-11.81950072,-8.270287804,-7.785549904,-3.34927669,-13.891980171203613,-14.647615432739258,-12.664117813110352,-12.925579071044922,-14.056119918823242 -1728,1728,M115A,-0.056622202,-0.068531384,-0.041467528,-0.014917788000000001,-1.660348986,0.004916551,-0.08350287599999999,-0.029741528,0.000584594,-0.036433507000000004,-0.100629261,-0.05160791,-0.031327145,0.03360058,-0.063436156,-1.496845816,-1.823852155,0.528379095,1.312400113,-7.657069527999999,-6.2566417539999994,-9.884267883,-9.415676285,-6.702970992999999,-6.025790726,-5.331669625,-2.545473917,-10.752588272094727,-13.626188278198242,-10.067193984985352,-12.163782119750977,-14.214709281921387 -1729,1729,M115C,0.032658348,-0.147687105,-0.028378116000000002,-0.039747957,-2.29634603,0.08279916400000001,-0.072921218,0.13823791400000002,-0.07788031299999999,-0.11578217800000001,-0.179592031,-0.002883751,-0.05387248,-0.025741882,-0.053754030999999994,-1.702029922,-2.890662137,0.845256399,1.320221315,-11.94820169,-10.82647069,-13.7040987,-13.11784296,-12.2934129,-9.799183205,-7.311900375,-4.765233907,-13.06333065032959,-17.351661682128906,-13.457756042480469,-13.606234550476074,-18.054702758789062 -1730,1730,M115E,-0.077968902,-0.046352078,-0.18108629699999998,-1.448695008,-2.747736235,0.019163441,-0.141224768,-0.014713035,0.265702033,0.000687946,-0.09339210099999999,-0.040308689,-0.321863904,-1.227640216,-1.6697498,-2.510606212,-2.9848662569999997,0.752470486,0.730520507,-11.95940157,-10.22333407,-13.17702732,-13.41546438,-11.32630573,-11.65487634,-7.936900214,-5.622652144,-14.122146606445312,-19.09501075744629,-14.631387710571289,-17.62935447692871,-15.75050163269043 -1731,1731,M115D,-0.038787071,-0.261846393,-1.326951676,-1.884608316,-2.42317742,-0.019872511000000002,-0.040484376,-0.037089765,0.060155795,-0.12666251,-0.397030275,-1.181590038,-1.4723133130000001,-1.794115463,-1.975101169,-2.158197204,-2.688157635,3.984665446,2.552604872,-15.14024923,-13.73035003,-16.68439781,-15.98276353,-15.43734532,-13.86638946,-9.962997698999999,-9.406221481000001,-15.390727043151855,-20.831777572631836,-13.687128067016602,-18.649192810058594,-17.007022857666016 -1732,1732,M115G,-0.006099182,-0.062980091,-0.38756376600000003,-1.4406256080000002,-3.110310358,0.039335313999999996,-0.09790577,0.085707406,-0.076015051,-0.045485791,-0.08047439099999999,-0.258669831,-0.5164577,-1.389641237,-1.491609978,-2.7855053510000003,-3.435115365,1.4141554490000001,0.829538387,-13.76476277,-12.63482731,-14.82893662,-15.19069814,-13.48751903,-12.68183276,-9.174082662,-7.131535802,-14.510762214660645,-18.602088928222656,-12.178749084472656,-16.80144500732422,-17.511634826660156 -1733,1733,M115F,-0.163045833,-0.040782916,-0.074139547,-1.506492191,-2.231619507,-0.032316376,-0.144913936,-0.18117772899999998,0.0190297,0.024832119,-0.10639795099999999,-0.02900914,-0.11926995300000001,-1.390926572,-1.62205781,-2.031214725,-2.432024288,2.6859881519999997,1.783490196,-7.682103101,-4.912254471000001,-10.81711462,-5.300588295,-9.395210251,-7.985347862,-4.142649948,-1.6633750219999999,-8.324396133422852,-13.299701690673828,-9.930842399597168,-11.414230346679688,-12.663420677185059 -1734,1734,M115I,-0.008825115,-0.017988973999999998,-0.033020477,0.013823225,-0.6841602940000001,-0.027353372999999997,-0.007512107,-0.010138123,0.104334031,-0.031112834,-0.004865114,-0.06977523599999999,0.0037342829999999997,-0.053054419000000005,0.080700868,-0.44144627799999997,-0.92687431,1.357250895,1.793329789,-4.6838435469999995,-3.39446933,-6.379566269,-4.6164899219999995,-4.610214729,-4.4184774860000005,-3.618939953,-1.341572605,-6.956181049346924,-10.715078353881836,-8.147505760192871,-10.404803276062012,-9.852899551391602 -1735,1735,M115H,-0.121289784,-0.13370729,-0.17739117399999998,-1.510988192,-2.694574602,0.012189846,-0.131769805,-0.11080976199999999,0.034709904,-0.09946688,-0.1679477,-0.167157203,-0.187625144,-1.4247772509999999,-1.5971991330000002,-2.265980248,-3.123168955,0.743968995,0.7186011459999999,-12.74549892,-12.85342976,-15.10646534,-13.59494257,-11.84877366,-10.32388329,-7.183928192000001,-4.630262733,-14.310062408447266,-18.947280883789062,-7.120208740234375,-15.367142677307129,-16.237777709960938 -1736,1736,M115K,-0.137168453,-0.07578979799999999,-0.077706493,-1.90351206,-1.942081163,0.040139334,-0.082431539,-0.191905367,0.14076329699999998,-0.063544973,-0.08803462199999999,-0.054065453,-0.101347533,-1.302218217,-2.5048059019999998,-1.967329954,-1.9168323719999998,2.815642752,1.931521494,-11.82922132,-11.58241544,-12.67465241,-13.0703722,-11.3271446,-10.49152195,-7.685133571000001,-5.080711508,-12.283647537231445,-15.743396759033203,-14.03371810913086,-15.627233505249023,-13.998968124389648 -1737,1737,M115L,-0.124186365,-0.098778892,-0.045003608,-0.040834802999999996,-0.112630744,0.001252237,-0.119539652,-0.128833077,0.050102232999999996,-0.068261582,-0.129296201,-0.075643276,-0.014363939,-0.035239433,-0.046430173,-0.083377853,-0.141883635,1.363850935,2.355303888,-3.897132072,-2.424484856,-4.911321648,-3.2678543010000003,-5.733329231,-3.1486703260000004,-3.94103758,-0.43244120700000005,-5.545146942138672,-9.734841346740723,-6.95781135559082,-6.381048202514648,-8.57111930847168 -1738,1738,M115N,-0.042723175999999995,-0.041464127,-0.045461202,-1.565522461,-2.30546101,0.039907677,-0.055279293,-0.030167057999999997,0.146515626,-0.046895215,-0.036033038999999996,-0.060710157,-0.030212246,-1.51353474,-1.617510182,-2.405294109,-2.205627911,0.8031298920000001,0.7110049279999999,-14.702565099999997,-14.01788326,-15.68131265,-15.77742808,-14.01445329,-14.02174821,-9.962997698999999,-9.406221483,-14.51119613647461,-18.078670501708984,-11.96776008605957,-15.209378242492676,-15.49394702911377 -1739,1739,M115Q,-0.16367383,-0.084851946,-0.008220067,-0.052392805,-1.057211717,0.054061539000000006,-0.185895163,-0.14145249599999998,0.06405667,-0.016418943999999998,-0.153284947,0.013923461000000002,-0.030363595,-0.028140959,-0.076644651,-0.7656969579999999,-1.348726476,0.834080863,1.4121297030000002,-9.32518147,-8.043374817,-11.15993693,-10.32548768,-8.300877731,-8.796230194,-6.2145198079999995,-4.794254427,-11.481282234191895,-16.955116271972656,-11.123729705810547,-14.020821571350098,-13.492125511169434 -1740,1740,M115P,-0.07672465099999999,-0.156759658,-1.372273813,-1.943167901,-2.825104778,0.016328867,-0.068898961,-0.08455034,0.03004814,-0.11103984800000001,-0.202479467,-1.413232825,-1.3313148000000001,-1.848113163,-2.038222638,-2.500990443,-3.149219113,4.1214818,2.548249186,-10.77149086,-10.00011649,-12.61098505,-12.03655227,-10.74829528,-8.461505203,-6.08220368,-3.41587074,-15.02088737487793,-16.411165237426758,-14.65084457397461,-13.695842742919922,-15.63374137878418 -1741,1741,M115S,-0.029678192000000003,-0.07116084,-0.03462944,-0.713154795,-2.116785912,0.03058248,-0.086401727,0.027045343,0.01516303,-0.040015366000000004,-0.10230631300000001,-0.082809325,0.013550446,-0.346626666,-1.079682923,-1.838772443,-2.39479938,1.52920832,1.387411341,-11.30751804,-10.53424852,-12.3439129,-12.62952574,-10.67317348,-10.35672956,-7.185035872,-4.660588547,-12.927715301513672,-15.522926330566406,-10.869976997375488,-12.796487808227539,-14.977560997009277 -1742,1742,M115R,-0.138576712,-0.08626314800000001,-0.064304828,-0.378250543,-1.9672593319999998,0.020707342,-0.154541892,-0.122611531,-0.000198898,-0.049448268,-0.12307802699999999,-0.054584279000000006,-0.07402537599999999,-0.19536805899999998,-0.561133027,-1.7516593059999999,-2.182859357,1.246257237,1.35406467,-9.835787199,-9.539482368,-12.11038084,-11.22650954,-8.888504303,-7.414058945,-6.487128912999999,-3.452822007,-13.987813949584961,-15.777685165405273,-12.287487983703613,-15.735958099365234,-14.584573745727539 -1743,1743,M115T,-0.106577522,-0.055964106,-0.016948808,-1.198464385,-1.986188766,0.032687247999999995,-0.110913919,-0.102241124,0.047646272999999996,-0.038899405,-0.073028807,-0.041890821,0.007993205,-0.873435705,-1.523493065,-2.00343424,-1.968943291,2.182368381,1.5501801769999999,-9.322909662,-9.246922295,-9.679179863,-11.04959677,-8.203036575,-8.435812805,-6.546711579,-2.5108215019999998,-10.793614387512207,-12.617894172668457,-9.74759292602539,-11.840356826782227,-12.711834907531738 -1744,1744,M115W,-0.17456010600000002,-0.27625793,-1.3987629830000001,-2.184385601,-2.906943098,0.025950839,-0.19703152899999998,-0.152088683,0.11309187,-0.124517879,-0.427997981,-1.3527256890000001,-1.444800277,-1.8983043240000002,-2.4704668780000003,-3.1074841060000002,-2.7064020889999996,2.5503311280000003,1.055091931,-12.7827295,-11.65941707,-15.46047152,-12.52841714,-14.11321976,-10.15212202,-7.098840595,-4.05813142,-14.125081062316895,-17.524356842041016,-13.183404922485352,-14.838862419128418,-16.14588165283203 -1745,1745,M115V,-0.13470765099999998,-0.058465645,-0.08982387900000001,-0.039572447999999996,-1.68219455,0.06425125799999999,-0.12646585300000002,-0.142949448,0.0190297,-0.024681178999999998,-0.09225011,-0.09606245,-0.083585307,-0.021666373,-0.057478522000000004,-1.589698152,-1.7746909469999999,0.811550422,1.325087332,-6.050000311,-5.089568938999999,-6.7020296020000005,-5.394023697000001,-7.138596581,-5.925782738,-4.4929994330000005,-1.520890789,-8.121284484863281,-11.959721565246582,-9.934367179870605,-11.433361053466797,-12.133282661437988 -1746,1746,M115Y,-0.08959731800000001,-0.035835628,0.006440156999999999,-1.5867161509999999,-2.522258013,0.017847125,-0.099426233,-0.079768403,-0.027502625,-0.050612729,-0.021058527,-0.01453207,0.027412383,-1.263133253,-1.9102990480000002,-2.4211605119999997,-2.623355514,0.785261256,0.7315211540000001,-11.77371922,-10.10593707,-15.19355828,-10.76927687,-12.00707725,-10.79274661,-5.849446893,-1.6157449380000002,-13.226640701293945,-16.862911224365234,-12.149171829223633,-14.27668571472168,-15.056008338928223 -1747,1747,T116A,0.09639473900000001,-0.012390102,-0.042528551,-0.001876493,-1.3788882340000002,0.032008052,0.065276668,0.12751281,-0.151413632,0.078066843,-0.102847047,-0.057643337999999995,-0.027413762999999997,0.051185565,-0.05493855,-1.044282614,-1.7134938530000001,0.780854477,1.3606479740000001,-4.614339275,-4.161985672,-4.6212267460000005,-4.153857567,-5.838130637999999,-4.29649575,-5.179335489,-2.372269727,-8.942852973937988,-7.795607566833496,-8.333765983581543,-7.732699871063232,-8.711742401123047 -1748,1748,T116C,-0.08644798199999999,0.020035095,-0.029195316000000002,-0.025121597000000002,-1.5696690219999998,0.09548311699999999,-0.107448004,-0.065447959,-0.08100631,0.10409242699999999,-0.064022237,-0.000669527,-0.057721105,0.097499048,-0.147742242,-1.455091295,-1.684246748,0.533904654,1.31616875,-7.801314934,-7.0215245589999995,-7.528456032,-7.55381443,-9.330720345,-7.572059303,-8.612227385,-6.810902485,-11.935937881469727,-12.371870994567871,-11.092398643493652,-11.23801326751709,-12.242584228515625 -1749,1749,T116E,0.069504655,0.066137848,0.027460795,0.020299755,-0.001675007,0.023687633,0.02916211,0.10984719999999999,0.0013449820000000002,0.08523705699999999,0.04703863900000001,0.030376475,0.024545114,0.010780007,0.029819502999999997,0.009128111,-0.012478125,1.671448915,3.643209181,-6.229341185,-5.011655403,-5.123377747,-6.718684509,-7.8361045229999995,-6.456883743,-6.452198833,-4.01517444,-10.437643051147461,-10.641828536987305,-9.48569107055664,-9.349370956420898,-8.615555763244629 -1750,1750,T116D,-0.030855103999999998,-0.029356322999999997,0.022589177000000002,-0.016174991,-0.7672614109999999,0.085524086,-0.001411025,-0.060299182,-0.007220096,0.032587367,-0.09130001300000001,0.01243301,0.032745342999999996,-0.032087354,-0.00026262700000000003,-0.569440999,-0.965081822,0.7955026959999999,1.4483339780000002,-5.397210226,-4.51030629,-3.894584938,-6.098363991,-5.675298401,-6.8074975129999995,-6.857411849,-3.441201631,-9.44086742401123,-9.184308052062988,-8.95844841003418,-9.349614143371582,-9.036664009094238 -1751,1751,T116G,-0.037451251,0.003788104,-0.025471307999999998,-1.057255801,-1.92948211,0.067372468,0.007750278,-0.08265278,-0.142067122,0.04611395,-0.038537743,-0.017096333000000002,-0.033846282000000005,-0.798570221,-1.31594138,-2.207586762,-1.651377457,1.883066057,1.36353168,-7.436768065,-6.649058983,-6.841107506,-7.244508652,-8.544755043,-7.9044101410000005,-7.329533248,-5.764104996,-9.993918418884277,-10.506911277770996,-10.486328125,-9.958332061767578,-9.830183029174805 -1752,1752,T116F,-0.024081097000000003,-0.01206305,0.008642252,-1.341195415,-2.045538289,0.065804654,-0.021759234,-0.026402959,-0.089961153,0.038742007,-0.062868107,-0.022084492,0.039368995,-0.650529216,-2.0318616130000002,-1.85135772,-2.2397188569999997,1.9071971230000002,1.487728217,-9.036252297999999,-7.6808108289999995,-8.275699295,-8.774218239,-11.28936111,-9.16117202,-8.766760603,-7.1646290839999995,-12.277220726013184,-10.511784553527832,-12.18429183959961,-12.078861236572266,-12.530820846557617 -1753,1753,T116I,-0.029547712,-0.036664545,-0.06452384900000001,-0.068939464,-1.5478838990000001,0.077119354,-0.011940481999999999,-0.047154941,-0.029644942,-0.002965925,-0.070363164,-0.063844135,-0.065203562,0.028888379,-0.166767306,-1.535769004,-1.559998793,0.62964893,1.3154106190000001,-7.1599022670000005,-6.423829994,-7.775798553,-6.781250664,-8.418593834,-6.4000382920000005,-7.352200868,-5.955867112999999,-10.813626289367676,-8.969714164733887,-9.7991361618042,-10.108113288879395,-10.332008361816406 -1754,1754,T116H,0.02698576,-0.01569922,0.029027382,-1.036932022,-2.348609979,0.011537435,0.040118252,0.013853266999999999,-0.026944657,-0.000513047,-0.030885392,0.026332495,0.031722269,-0.664338379,-1.409525665,-2.380867044,-2.316352914,1.6694086419999998,1.274405174,-8.265350033999999,-7.846726135,-7.334351784,-8.873594246,-8.771982643,-8.50009536,-9.770391327,-9.847493683,-12.224266052246094,-11.526867866516113,-10.653990745544434,-11.232254028320312,-11.41269588470459 -1755,1755,T116K,-0.026848944,-0.03467044,-0.029296087999999998,0.011737576999999999,-1.586312554,0.08553243199999999,-0.021459618,-0.03223827,0.10192437300000001,0.052448811,-0.12178969,-0.01356123,-0.045030945,0.073327867,-0.049852714000000006,-1.451992006,-1.720633101,0.5722939539999999,1.3157837209999999,-4.458234241,-3.6812696380000003,-3.9949545289999997,-4.943261818,-5.849586577999999,-3.82209864,-5.626272579,-3.5536470110000002,-10.057906150817871,-9.739442825317383,-9.440719604492188,-8.85011100769043,-10.58511734008789 -1756,1756,T116M,0.026839618,0.001257632,-0.00284641,0.008295448,-1.060159582,0.075087842,0.015370074,0.038309162,0.09793389,0.029434847000000004,-0.026919584,0.0013549279999999998,-0.007047748,0.015276936000000001,0.001313959,-0.8225803490000001,-1.297738815,0.6806257840000001,1.371287564,-7.733835994,-6.800856727999999,-7.749093094,-7.481633636000001,-9.084618591,-7.552977921,-8.106534065,-6.655915322999999,-11.103836059570312,-8.237701416015625,-9.659893035888672,-9.876787185668945,-10.29856014251709 -1757,1757,T116L,0.020980627,0.015232158999999999,0.009699731999999999,0.008278787,-0.8311066909999999,0.066479028,0.032834317,0.009126937,-0.006812116,0.047584838,-0.017120521,0.014663819,0.004735645,0.022185026,-0.005627452,-0.658472336,-1.003741046,1.097736136,1.538400506,-6.853724618999999,-5.844785706000001,-6.786302765,-6.986213089,-8.223928528,-6.427393005,-7.641911601,-5.552171552999999,-9.532622337341309,-8.665452003479004,-8.52043628692627,-9.842036247253418,-9.588967323303223 -1758,1758,T116N,-0.047183178,0.021534895,0.014729906000000001,0.039494819,-0.5730477279999999,0.090701393,-0.050073584000000004,-0.044292770999999995,0.001700524,0.083574623,-0.040504833,0.014603877,0.014855934,0.09619652599999999,-0.017206889,-0.390212785,-0.75588267,0.48237641299999995,1.4122088480000001,-4.0038519169999995,-3.77908374,-2.76343399,-5.301901199,-4.235599068,-3.939241585,-4.7429655330000005,-3.9558742789999997,-8.204294204711914,-8.45379638671875,-7.63580322265625,-7.5382914543151855,-8.74742317199707 -1759,1759,T116Q,0.085722727,-0.005381476,-0.001254338,0.01740643,-0.500701472,0.040098109,0.076431412,0.09501404199999999,0.010702508999999999,0.016964311,-0.027727262000000003,-0.027338078,0.024829402999999996,-0.003220111,0.03803297,-0.33382594,-0.667577003,1.3392136890000002,1.879034207,-5.649044252,-4.954283035,-5.140034462,-6.070448761000001,-6.811470032000001,-5.26898497,-6.587596811,-4.5443570189999996,-10.660065650939941,-9.637853622436523,-8.296663284301758,-9.23421859741211,-9.4515962600708 -1760,1760,T116P,-0.046010731,-0.037404854,0.007097428,0.010524426000000002,-1.6762142930000001,0.034947385,-0.05518299,-0.036838472000000004,0.058135102,0.026031923999999998,-0.10084163199999999,0.024999426,-0.010804571,0.085652293,-0.064603441,-1.5106497369999998,-1.8417788480000001,0.46205937700000005,1.309133238,-4.195094287,-3.3560112610000004,-4.115027458,-4.071187141,-6.431942627000001,-3.001302948,-5.99379716,-1.898445868,-7.89077091217041,-8.635964393615723,-7.37447452545166,-8.773212432861328,-8.914300918579102 -1761,1761,T116S,0.016682238999999998,-0.007373946,-0.031960188,-0.02026366,-0.073522367,-0.025618872,0.014746663,0.018617814,0.030712057,0.019879999,-0.03462789,-0.028017977000000003,-0.035902397999999995,-0.004516592,-0.036010727,-0.009275676,-0.137769058,1.171406769,2.578300048,-0.9724638729999999,-0.8109547420000001,-0.307503822,-1.231742119,-1.902097954,-0.610020729,-2.6544689619999997,-0.47846233899999996,-4.419510841369629,-5.098145484924316,-5.368706703186035,-5.21994686126709,-4.78298807144165 -1762,1762,T116R,0.006765715,-0.012477792,-0.055089574,-0.02870607,-2.094839733,0.05584066099999999,0.021516828999999998,-0.0079854,-0.056438119,0.019530131000000003,-0.044485714,-0.05862743,-0.051551717000000004,0.018878483,-0.076290622,-1.7783367819999998,-2.411342683,0.622077378,1.304595661,-3.6911196210000004,-3.88523246,-3.1528385389999998,-4.065354773999999,-3.4462431560000004,-3.9059291760000003,-4.744740371000001,-3.333135843,-10.621520042419434,-9.13027572631836,-9.108072280883789,-9.542440414428711,-10.560627937316895 -1763,1763,T116W,0.00755318,-0.008474647,-0.956158623,-1.884637119,-2.491227844,0.044729514000000005,0.01371971,0.001386649,-0.028409395,0.026117757000000002,-0.04306705,-0.864858268,-1.047458977,-1.706536059,-2.062738179,-2.092071505,-2.890384182,3.521989718,2.239853713,-9.128722887999999,-7.850205513,-8.478898636,-8.918624649,-10.97518143,-9.420704216,-9.521499716000001,-8.649720343,-15.155133247375488,-13.101728439331055,-13.897655487060547,-14.108747482299805,-14.216512680053711 -1764,1764,T116V,-0.003884605,0.016952352,-0.004320679,0.021454367000000002,-1.5398455869999998,0.061938764,-0.009394143,0.001624934,-0.131484986,0.066963829,-0.033059126,-0.00981907,0.001177713,0.047698082999999995,-0.00478935,-1.5023209519999998,-1.5773702219999999,0.13344225,1.300237148,-8.139961909,-7.088425179,-8.937940758,-7.674339752000001,-9.430620529,-7.56848333,-8.819686118,-7.223782664,-10.671899795532227,-10.188605308532715,-10.03195858001709,-9.678637504577637,-10.861064910888672 -1765,1765,T116Y,-0.060882052,-0.039298247,-0.01677034,-0.728765137,-2.162579891,0.112041439,-0.027246054,-0.094518049,-0.06344302,0.025227443999999998,-0.10382393699999999,-0.0067199830000000006,-0.026820696,-0.300444298,-1.157085975,-2.250251174,-2.0749086080000003,1.319165487,1.294205984,-8.985182095,-7.471534233,-8.631373306,-8.698054375,-11.08645425,-9.038494307999999,-9.05453873,-7.473254964,-12.735809326171875,-11.874271392822266,-11.428166389465332,-12.412949562072754,-12.953950881958008 -1766,1766,V117A,-0.250511096,-0.025107282,0.019636518000000002,-1.213244232,-1.9474422409999999,0.024692884,-0.007830031999999999,-0.49319216,-0.022486147999999997,0.045369985999999994,-0.095584549,0.015459293999999998,0.023813741,-0.8125354020000001,-1.6139530619999998,-1.9790380930000002,-1.9158463890000001,2.007254243,1.478538322,-6.256039713,-5.98053302,-4.507085593999999,-7.746361702000001,-8.587839942999999,-4.458378304,-5.207618673,-1.8478204480000002,-6.029028415679932,-8.513938903808594,-8.048251152038574,-8.434767723083496,-8.654176712036133 -1767,1767,V117C,-0.226375298,-0.006504276999999999,0.032854397,-1.201150381,-2.283712065,0.08412371199999999,-0.012151081000000001,-0.440599515,-0.18045606399999997,0.000650069,-0.013658621999999999,0.053712199,0.011996595,-1.035231867,-1.367068895,-1.7631647209999999,-2.8042594089999997,2.804048289,2.085719938,-10.95268839,-10.00516948,-8.347687782000001,-14.83530769,-12.09111189,-9.484165131000001,-8.381039762999999,-6.306644863,-11.227060317993164,-11.92282485961914,-12.196414947509766,-11.761836051940918,-12.859134674072266 -1768,1768,V117E,-0.276191234,-0.007437206,-0.525781157,-1.620442323,-2.565433678,-0.038608921000000004,0.0025622170000000003,-0.554944684,-0.015794267,-0.002937629,-0.011936782,-0.196379794,-0.8551825190000001,-1.384373259,-1.8565113869999998,-2.179588135,-2.95127922,2.433421696,1.5198229769999998,-11.76438717,-11.25055074,-8.804499214,-14.84908593,-13.84348036,-10.07431959,-9.511233958,-9.330018295,-11.208080291748047,-12.933783531188965,-11.090082168579102,-12.524446487426758,-12.055423736572266 -1769,1769,V117D,-0.30705446399999997,-0.9162908340000001,-1.64686067,-2.214708265,-2.88154837,-0.041883015,-0.025988182000000002,-0.588120746,0.036429266,-0.934588237,-0.89799343,-1.7743309219999999,-1.5193904169999999,-1.9209317019999999,-2.5084848280000003,-2.8588140810000002,-2.904282658,3.371710382,1.384173742,-12.07038595,-11.42261776,-8.848602248999999,-15.74962344,-13.75812628,-10.57296002,-9.511233958,-9.330018295,-12.306371688842773,-13.976789474487305,-13.113065719604492,-13.756118774414062,-14.781025886535645 -1770,1770,V117G,-0.259487311,-0.033888666,-1.108468384,-2.0105135290000002,-2.630401382,0.039384244,-0.061763724000000006,-0.457210897,-0.0038950440000000003,-0.034730723,-0.033046608,-1.170246244,-1.046690524,-1.8958417109999999,-2.125185346,-2.6940620969999998,-2.566740666,2.450018708,1.058305433,-9.32960853,-9.608780075,-6.6088361429999996,-12.10435221,-9.609064232,-8.717009987,-6.628344824,-4.894434212,-10.442648887634277,-13.039613723754883,-12.69926929473877,-11.864990234375,-13.095198631286621 -1771,1771,V117F,-0.188603312,-0.01185563,-0.03228895,-1.048876452,-1.859549574,0.089330663,0.041944521,-0.419151145,-0.052388069,-0.000779093,-0.022932167000000003,-0.063102807,-0.0014750920000000001,-0.694003426,-1.4037494780000002,-1.794613104,-1.924486044,2.064150368,1.576902693,-7.688964812999999,-7.261733582000001,-4.750369385,-11.56991686,-7.709894912999999,-7.152909325,-6.167704493,-3.2416700360000004,-9.60901165008545,-10.705453872680664,-11.217689514160156,-9.699713706970215,-10.524222373962402 -1772,1772,V117I,-0.264380752,-0.02920765,0.056501333,-0.049630350999999996,0.022859979,-0.009719234,-0.065094785,-0.463666719,-0.06694679,0.027903845,-0.086319145,0.06593376599999999,0.047068899000000004,-0.010976191000000001,-0.08828451,0.076875851,-0.031155894,1.114094106,2.7185885560000003,-1.7665006769999998,-1.233026207,-0.7732630229999999,-2.908008606,-2.447022835,-1.471182716,-3.072235679,-0.578043005,-4.546383857727051,-5.535000801086426,-6.013505935668945,-4.505201816558838,-4.515050888061523 -1773,1773,V117H,-0.289175098,-0.026007544,-0.250962872,-1.640489799,-2.170829267,0.028951614,-0.064845118,-0.513505078,0.142667504,-0.025152627,-0.02686246,-0.127544045,-0.374381698,-1.447331093,-1.8336485040000001,-2.28830346,-2.053355074,0.710398312,0.708163689,-12.16490238,-11.27475385,-8.348230751000001,-18.58385271,-12.89511638,-9.722558227999999,-8.435883383,-6.316306537000001,-13.664643287658691,-13.579486846923828,-13.848752975463867,-14.02754020690918,-14.598520278930664 -1774,1774,V117K,-0.314088284,-0.094016622,-1.227326892,-1.775715455,-2.743585555,0.048729117999999995,-0.011429462,-0.616747106,-0.367976785,-0.067092974,-0.12094027,-1.115719431,-1.338934353,-1.767470189,-1.78396072,-2.7053525689999995,-2.78181854,2.569394654,1.1861232240000001,-11.77331802,-11.00674554,-9.195935226,-15.643878400000002,-13.41667705,-9.603353874,-8.795120501,-7.59899137,-11.411765098571777,-14.177938461303711,-14.434464454650879,-14.661470413208008,-13.685344696044922 -1775,1775,V117M,-0.24221695399999998,-0.06286596,-0.036932776,0.048201832,-0.048577407999999996,-0.028879732999999998,-0.011139061,-0.473294847,-0.284639579,-0.027378655,-0.09835326400000001,-0.087616954,0.013751403,0.019427763,0.076975901,-0.08107607900000001,-0.016078737,1.4355039180000002,2.458437854,-4.363642732,-4.042321251000001,-3.356096565,-5.572183731,-4.242629311,-4.604982803,-5.326074086,-3.197302179,-6.433712482452393,-9.035127639770508,-8.722410202026367,-6.7116498947143555,-8.300458908081055 -1776,1776,V117L,-0.238267232,-0.021159241000000002,0.024611372000000003,0.01605092,-0.058099032,-0.020830975,-0.041196216,-0.435338248,-0.11787688199999999,0.043942275,-0.086260757,0.049325767,-0.00010302299999999999,0.047415753,-0.015313914,-0.010972009,-0.105226054,1.185372534,2.546179649,-1.5366615630000002,-0.507659531,-0.8648358840000001,-2.666406036,-2.114310829,-1.530095535,-2.5656178730000003,0.22134431899999998,-5.5687174797058105,-6.3162384033203125,-6.132758140563965,-5.228254318237305,-4.897075176239014 -1777,1777,V117N,-0.32362586600000004,-0.046714637,-0.017821474,-1.321835129,-2.185462835,0.082775303,-0.039109859,-0.608141872,-0.460730839,0.042462565,-0.13589183900000001,0.079938528,-0.115581475,-1.165148653,-1.478521605,-2.144423718,-2.226501952,0.293690638,0.703575332,-10.22056292,-9.215030731,-6.933738625,-14.49957343,-11.64967973,-8.804792068,-7.004085511,-4.725911779,-11.809779167175293,-12.676959037780762,-13.660429954528809,-13.277453422546387,-13.693741798400879 -1778,1778,V117Q,-0.374484991,-0.113015164,-0.043925760999999994,-1.51255185,-2.298832998,0.01228646,-0.11930809099999999,-0.62966189,-0.14017870300000002,-0.070041534,-0.15598879300000001,-0.056011887999999996,-0.031839634,-1.254506941,-1.7705967580000002,-2.607362668,-1.9903033280000002,0.954681013,0.7539637929999999,-10.34271522,-9.846376663,-8.172675468,-13.49672191,-11.7785806,-8.419221481000001,-8.082229509,-5.919210967000001,-11.641602516174316,-11.683599472045898,-12.6679105758667,-12.817361831665039,-12.139039993286133 -1779,1779,V117P,-0.282371759,-0.055102390999999994,-0.023587482000000003,-1.1312305329999999,-1.988141729,0.021275363,-0.052658825,-0.5120846929999999,0.04635364,-0.016095122,-0.094109659,-0.02752038,-0.019654583,-0.7190926670000001,-1.543368399,-1.945114552,-2.031168906,1.878424839,1.435540398,-8.74989317,-9.146503532,-6.739240585,-10.21970612,-9.334212524,-8.309803085,-5.847463461,-4.28899689,-11.936016082763672,-10.722989082336426,-10.469919204711914,-11.37175464630127,-11.564796447753906 -1780,1780,V117S,-0.348059451,-0.035935456,-0.28899662,-1.568728596,-2.625799367,0.023947219,-0.141448093,-0.554670808,0.080372727,0.00389917,-0.075770082,-0.172310849,-0.40568239100000003,-1.435725411,-1.70173178,-2.43806578,-2.813532953,1.0908471659999999,0.750603818,-10.37309728,-8.974818557999999,-7.7403716739999995,-14.07290837,-11.35054575,-9.726842072,-7.170111636000001,-5.234485493999999,-10.618903160095215,-10.837873458862305,-12.152338027954102,-12.275259971618652,-12.231415748596191 -1781,1781,V117R,-0.24361180100000002,-0.11642260300000001,-1.3025670870000001,-2.105439961,-2.851083992,0.055374350999999995,-0.049218023,-0.43800557799999995,-0.10942657,-0.013825151,-0.219020054,-1.261835015,-1.3432991580000002,-1.866251895,-2.344628026,-2.563802119,-3.138365864,2.719713343,1.25561952,-10.26244764,-9.830498306,-8.016289116,-14.15769828,-11.63069751,-7.67705497,-6.915723326,-4.487000931,-12.84451961517334,-12.90001106262207,-13.300363540649414,-12.38611888885498,-13.128231048583984 -1782,1782,V117T,-0.250115225,-0.029834127999999998,0.012580353,-0.010530528999999999,-1.3706346219999999,0.014738635,-0.063904121,-0.436326329,-0.048098706,-0.018617994,-0.041050261,-0.005479869,0.030640574,-0.03461359,0.013552531999999999,-1.218751656,-1.5225175880000001,0.791332732,1.346513606,-7.932260651,-7.3525056,-6.1326936110000005,-9.979522179,-9.792545494,-6.404036369,-5.806539921000001,-4.179871568,-8.175114631652832,-8.44458293914795,-9.594696044921875,-9.628098487854004,-8.785375595092773 -1783,1783,V117W,-0.255943221,-0.07443053,-1.351495715,-2.25605126,-2.962481988,0.082008652,-0.035083687,-0.476802755,0.022862882999999997,-0.018388764,-0.130472295,-1.337376396,-1.365615033,-1.961098431,-2.551004089,-2.978162057,-2.9468019180000002,0.676915488,0.066440147,-6.81026353,-5.538782013,-5.907137848,-10.82712364,-6.731381027,-5.04689312,-5.245307703,-2.573251214,-13.905914306640625,-14.025117874145508,-13.329364776611328,-14.217864036560059,-14.368796348571777 -1784,1784,V117Y,-0.341380559,0.018609143999999998,-0.034203576,-1.394499607,-2.304200425,0.01260048,-0.125092714,-0.557668403,-0.14017870300000002,0.030374065,0.006844223000000001,0.082006953,-0.150414105,-1.287463246,-1.5015359680000002,-2.057854539,-2.5505463109999997,2.363392742,1.566767692,-8.398606474,-8.399777885,-4.581695366,-13.35265824,-8.276664719,-7.38223616,-5.916726252,-2.124789941,-12.69825553894043,-12.962127685546875,-12.406478881835938,-12.455748558044434,-13.256975173950195 -1785,1785,R118A,0.08617433699999999,0.036147797,0.054661962,0.036302631,0.057780066,-0.030544937999999997,0.08239150599999999,0.089957168,-0.113598084,0.005040887,0.067254706,0.049513357,0.059810565999999996,-0.018988636,0.091593898,0.025219403999999997,0.090340727,1.129499537,2.631264114,2.608249808,2.0674316409999998,1.33406282,4.326858444,2.398596985,2.9142991489999996,0.05331638599999999,-0.30335846699999997,-0.8731379508972168,-1.5054740905761719,-0.8320937156677246,-0.42600536346435547,-2.8215205669403076 -1786,1786,R118C,0.18278330199999998,0.082868515,0.089045377,0.082955726,0.022429658999999998,0.06474849,0.201817594,0.163749009,-0.062667992,0.058436287999999996,0.10730074099999999,0.066608316,0.11148243699999999,0.047041677999999996,0.11886977300000001,0.0064979619999999995,0.038361356,1.362070184,2.808701961,-4.961308159,-5.524642592999999,-4.908453377,-5.097004501,-4.093757217,-5.182683105,-6.382058056,-7.535893982999999,-8.34609603881836,-8.343809127807617,-7.008092880249023,-6.862394332885742,-9.40926742553711 -1787,1787,R118E,0.026017109,0.07171736,0.039529654,0.012008208999999999,0.049050117000000004,0.012406799,0.059711985999999995,-0.007677769,-0.046873724000000005,0.036373947999999996,0.107060771,0.009189876,0.069869431,-0.040645994,0.064662411,0.022645952,0.075454281,1.319069709,2.77049399,-0.060092778,-0.681121918,-0.43458886700000005,0.004133987,0.23882345600000002,0.572289452,-1.782542163,-1.1480329409999999,-4.123835563659668,-5.1327738761901855,-2.8783297538757324,-3.155595302581787,-5.343010902404785 -1788,1788,R118D,0.02625042,-0.008629554000000001,0.027487297999999997,-0.005125526,0.030534581,-0.018908223000000002,0.059340779,-0.00683994,0.481400053,0.029966262,-0.047225369,0.04894379,0.006030805,-0.004127965999999999,-0.006123085,-0.015306891999999999,0.076376053,1.305479997,2.628227821,-0.851754948,-1.174133881,-1.29758036,-0.946357597,-0.152816086,-0.687886818,-1.49805114,-1.726436461,-5.196934223175049,-5.966366767883301,-4.01430606842041,-4.819190979003906,-6.222354412078857 -1789,1789,R118G,-0.016353398,0.007237049000000001,0.016317243999999998,0.001971505,0.015036121999999999,0.029744833999999998,0.04553641,-0.078243206,-0.036100363999999996,0.017650653,-0.0031765559999999997,0.0066446019999999995,0.025989886,-0.010657668,0.014600678,0.020148635,0.009923609,1.257875546,2.740139213,2.42835004,1.753671661,1.117619255,3.419369751,3.0142286680000003,2.836860863,1.3589743980000002,-1.007176965,-2.4098620414733887,-2.0873770713806152,-1.7610684633255005,-1.7350374460220337,-2.948268413543701 -1790,1790,R118F,-0.010086076999999999,-0.008922288,0.031678691,-0.00084538,-0.006853186,-0.046255189,0.017741545,-0.037913699,0.073475823,-0.018917714,0.0010731389999999999,0.026057801000000002,0.03729958,-0.018401478,0.016710718,-0.029195698,0.015489326000000001,1.261964956,2.478207252,-2.652566455,-3.590400818,-2.510470673,-4.472113533,-0.88971225,-1.800135002,-2.9794445539999996,-3.623692675,-5.623708248138428,-7.229949951171875,-7.2657012939453125,-5.738706111907959,-8.358488082885742 -1791,1791,R118I,-0.008065667,0.041606408,0.043735705,0.043729638,-0.472002342,0.087401726,0.053570593,-0.069701927,-0.067414427,0.049823183,0.033389632,0.064504984,0.022966425,0.039629253999999996,0.04783002099999999,-0.335535374,-0.608469309,0.9722927,1.639672269,-3.630767558,-4.32337056,-2.5682676769999997,-3.772211945,-2.8185148389999997,-4.671472771,-4.073915932,-3.211824015,-5.629276752471924,-7.265962600708008,-7.048750877380371,-5.905095100402832,-7.705564022064209 -1792,1792,R118H,0.06998799,0.02950257,0.07556677,-0.020113119,0.046338758,-0.039179097,0.06757181799999999,0.07240416200000001,-0.00036610699999999996,-0.000801822,0.059806961,0.018867698000000002,0.132265842,-0.041561794,0.001335557,-0.022527103,0.11520461800000001,1.276755325,2.5206573519999997,-1.7799450469999998,-3.265339722,-2.004851181,-1.9855953219999998,-1.0735904459999999,-0.570348564,-2.897583917,-2.8704265060000003,-5.084249019622803,-4.709011554718018,-3.608311653137207,-4.940761566162109,-6.2095232009887695 -1793,1793,R118K,-0.12431767099999999,-0.055915783,0.01440222,0.032936827,-0.042341403,-0.053301075,-0.038321845,-0.210313497,-0.193210606,-0.058148767999999997,-0.053682797000000004,0.031089862000000003,-0.002285422,0.062878735,0.0029949190000000004,-0.021870465,-0.06281234,1.199371564,2.585908336,-1.2274138209999998,-2.028689102,-1.3852400130000002,-0.9048282009999999,-1.060304016,-0.7580077740000001,-1.573049189,-1.262806123,-4.601762294769287,-4.2675089836120605,-4.129305362701416,-4.409120082855225,-4.717319965362549 -1794,1794,R118M,-0.020730537,-0.009793038,-0.012474862,-0.016744207,-0.024256937000000003,0.019387667,0.036246334,-0.077707407,-0.036339052999999996,-0.03359527,0.014009193999999999,-0.03632429,0.011374566000000001,-0.047594450999999996,0.014106038000000001,-0.042827215999999994,-0.005686658000000001,1.321427578,2.414619047,-4.22474585,-4.225494652,-2.982794655,-4.803388603,-3.74320961,-5.368841728,-3.807379678,-3.777869985,-6.281667709350586,-6.8793439865112305,-6.157662868499756,-5.5584821701049805,-7.911202907562256 -1795,1795,R118L,0.036529635,0.028522917999999998,0.07093257,0.03463397,-0.023411341000000002,-0.023285623999999998,0.067052425,0.006006844,-0.088475255,0.008423469,0.04862236599999999,0.029636287999999997,0.11222885199999999,-0.0028280809999999997,0.07209602,-0.03419249,-0.012630191,1.063767873,2.354444695,-2.9905242419999998,-4.022805885,-0.744396683,-3.386797646,-2.213631485,-4.58498951,-2.909018028,-1.461244213,-4.600726127624512,-5.80155086517334,-5.425301551818848,-3.9832472801208496,-6.251346111297607 -1796,1796,R118N,-0.018257246,0.048629175,0.052406512999999995,0.042307845999999996,0.040624438,-0.046720335,0.026298151000000002,-0.062812643,-0.098383544,0.066950968,0.030307381,0.104571415,0.00024161,0.023372939,0.061242752000000004,0.052310998,0.028937877,1.162116382,2.789158065,-1.870366907,-2.683146286,-2.278595535,-1.8045489959999998,-1.493231323,-1.092312393,-3.024305013,-3.58612226,-5.209722518920898,-4.912557125091553,-4.177842617034912,-4.733492374420166,-5.900051593780518 -1797,1797,R118Q,0.055458725,0.033137688,0.11043060099999999,0.089627048,0.110618312,-0.10126669699999999,0.055743762,0.055173687,0.036947915,0.045067875,0.021207499999999997,0.107073451,0.11378775099999999,0.054092652000000005,0.125161444,0.060884887,0.160351736,1.105709139,2.8104465239999996,-1.3078020609999998,-1.86728627,-0.799366371,-1.8247462840000002,-2.057256424,0.009645042,-2.338629866,-2.0911685419999997,-4.783679008483887,-3.7514944076538086,-3.81233549118042,-3.8696584701538086,-5.193442344665527 -1798,1798,R118P,0.03162797,0.013754581,0.04145012,-0.475285336,-1.724867907,0.029083611000000002,0.08681659800000001,-0.023560658999999998,-0.009085164,0.026438304,0.001070857,0.046332280999999996,0.036567958,-0.21141090399999998,-0.7391597679999999,-1.857268035,-1.592467778,1.1428302,1.328309473,-4.204341599999999,-4.525827843,-4.360792603,-3.671159897,-4.022478142,-4.4414495160000005,-4.718240439,-5.323603949,-7.645203113555908,-9.10741138458252,-6.56351900100708,-6.440874099731445,-8.281442642211914 -1799,1799,R118S,0.063759247,0.043443772,0.04895046,0.063100099,0.09075071300000001,-0.004211205,0.114919641,0.012598851999999999,0.078380518,0.015771137,0.071116407,0.045178804,0.052722116,0.037998827,0.088201371,0.031807283,0.149694143,1.069916017,2.663732896,1.7485659969999998,1.3212009279999999,0.540397499,2.547294426,1.931762077,2.402175056,-0.376137692,-1.2099188859999999,-3.0119333267211914,-2.2039928436279297,-1.6514416933059692,-2.6817636489868164,-4.392529487609863 -1800,1800,R118T,0.053708148,0.019056112,0.018983507,0.02255016,0.015904985,0.003673225,0.09837404699999999,0.009042248000000001,-0.131125372,-0.001719595,0.039831819,0.015743663,0.02222335,-0.009028314,0.054128632999999995,-0.020515891,0.05232586,1.160497553,2.4378376840000002,-1.062213403,-1.1225927279999999,-1.509501381,-0.441777153,-1.1628148729999999,-1.074380882,-2.8583738210000003,-3.2849989,-4.4975810050964355,-5.040643692016602,-4.343575477600098,-4.326440334320068,-6.321674823760986 -1801,1801,R118W,0.017369632,0.07646682099999999,0.057532255,0.069627325,0.068141592,0.009984405,0.083503656,-0.048764392999999996,0.061505468,0.044902379000000006,0.10803126199999999,0.019072551,0.095991958,0.029530175,0.109724474,0.029403334,0.10687985,1.070977887,2.607428009,-4.707745654,-5.198376587,-3.869727547,-6.208966713,-3.738145645,-4.52351178,-4.62424297,-4.591170078999999,-6.981933116912842,-8.306703567504883,-7.6718645095825195,-7.133598327636719,-9.22450065612793 -1802,1802,R118V,0.019249195,0.025173664,0.044162056,0.018263055,-0.175151046,0.031916276,0.054700097999999996,-0.016201708000000002,-0.011515468999999999,-0.011926443,0.062273771,0.06610550400000001,0.022218607999999997,-0.006275302,0.042801411,-0.178853345,-0.17144874699999998,1.321244515,2.083570169,-3.001961591,-3.7188921280000002,-2.92480423,-2.41732473,-2.5176491469999998,-3.431137718,-3.24651071,-4.011718749,-5.236245632171631,-7.104201793670654,-6.27075719833374,-5.322844982147217,-7.656652450561523 -1803,1803,R118Y,0.105373281,0.040647812,0.067758179,-0.006526441,0.022056821,0.012739138999999998,0.161771559,0.048975002000000004,-0.041478693,-0.042281124,0.12357674699999999,0.000468971,0.135047387,-0.034902182999999996,0.021849301,-0.068042977,0.112156619,1.3921976440000001,2.4332827740000003,-2.341448868,-3.676400009,-2.48361554,-4.356644783,-0.8637984009999999,-0.326785606,-3.560906808,-2.484003953,-5.926440238952637,-6.814388275146484,-7.095865726470947,-6.17733907699585,-8.259136199951172 -1804,1804,E119A,0.027917422,-0.014252553000000001,-0.041742661,0.020854251,-0.286135695,0.061169193,0.058886846,-0.0030520029999999997,0.09099220699999999,0.018368618,-0.046873724000000005,0.055265518,-0.13875084,0.018443246,0.023265255,-0.279481195,-0.292790195,1.640244272,2.228530588,-1.68036879,-1.041278931,-1.8619745030000001,-2.003862015,-1.675052582,-1.819675919,-2.930924778,-1.6687352830000002,-8.960140228271484,-7.357321739196777,-7.828346252441406,-6.686741352081299,-9.039817810058594 -1805,1805,E119C,0.063467143,-0.055601904,0.030413898999999998,-0.9618721859999999,-2.1288413530000003,0.13529427800000002,0.059121452000000005,0.067812834,0.302996022,0.030125346,-0.141329153,0.10798889699999999,-0.047161099000000005,-0.635704107,-1.288040265,-1.999425346,-2.258257359,1.791020157,1.409306824,-8.461060606,-7.017796204,-7.894433495,-9.320650803,-8.619765862000001,-9.45265667,-8.4950091,-6.548781087999999,-15.774931907653809,-15.751340866088867,-15.56794261932373,-12.417463302612305,-17.538719177246094 -1806,1806,E119D,-0.02953949,0.015749702,0.0046832209999999996,0.050086507999999995,0.050682024000000006,-0.056811682,0.018353202,-0.077432181,-0.11676206,0.12015654099999999,-0.08865713800000001,0.10298699800000001,-0.093620557,0.09828792800000001,0.0018850879999999998,0.028303368,0.073060679,1.1060094409999999,2.723212628,-1.697410106,-1.1668536379999999,-1.5903912580000001,-1.451865479,-2.279337151,-1.998603004,-3.5903736060000004,-0.287518404,-7.038674354553223,-6.230356693267822,-6.485901832580566,-4.686812400817871,-7.234342575073242 -1807,1807,E119G,0.08882199800000001,-0.020923239,-0.041675409,0.027915199999999998,-0.211259948,0.061434353,0.083606703,0.094037292,-0.07234292,0.015106902,-0.056953379000000005,0.047360835,-0.13071165199999998,0.035709092000000005,0.020121306999999998,-0.17471410699999998,-0.247805789,1.187118251,2.014754366,-3.717300769,-3.15910347,-3.364646149,-4.2241701130000004,-3.684490883,-4.154093231,-4.844490384,-3.7958123269999997,-11.87189769744873,-9.679096221923828,-10.00102710723877,-9.17517375946045,-10.816121101379395 -1808,1808,E119F,-0.11601630199999999,-0.046292864,-1.04424611,-2.17094009,-2.810730425,0.09012743699999999,0.024359346,-0.25639195,0.040553398,-0.012066131,-0.080519597,-0.872675434,-1.215816785,-1.7558363730000002,-2.5860438059999997,-2.629471381,-2.991989469,2.308789484,1.091189955,-8.788129854,-7.234076247999999,-6.9253349,-10.21703087,-8.918424095,-10.64578316,-7.264344361,-4.629417234,-16.39702606201172,-13.370716094970703,-15.403112411499023,-12.774402618408203,-14.706439971923828 -1809,1809,E119I,0.022108467000000003,-0.590078825,-1.4518714959999999,-1.883245091,-2.332929806,0.035654626,0.07846399700000001,-0.034247063,0.0030370370000000002,-0.56794674,-0.612210909,-1.49651819,-1.4072248019999998,-1.892128346,-1.8743618359999998,-2.8626733669999997,-1.803186245,2.972448482,1.26469962,-8.443008742,-6.503017258,-7.274406425,-9.010527183999999,-8.441376052999999,-10.98571679,-7.693987913,-5.58848318,-14.030813217163086,-11.582315444946289,-14.255744934082031,-11.240891456604004,-14.470291137695312 -1810,1810,E119H,-0.049829862999999995,-0.073091612,-0.035737184,0.007486847,-0.909007435,0.086480449,-0.021189298999999998,-0.078470427,0.09099220699999999,0.011352828,-0.15753605099999998,0.057662512,-0.129136879,0.01457309,0.000400604,-0.7372252979999999,-1.080789571,0.7568045990000001,1.400119071,-6.718770551,-6.011270592000001,-6.575578011,-6.395580863999999,-6.847009132,-7.764414154,-6.481936295,-4.900684251,-12.623518943786621,-10.37308120727539,-11.131869316101074,-10.127420425415039,-12.403703689575195 -1811,1811,E119K,-0.06832025900000001,-0.010494547,-0.028575661000000002,0.0017721929999999998,-1.414133549,0.08607703400000001,0.06338697900000001,-0.200027497,-0.063909753,0.053256934000000006,-0.07424602799999999,0.060516377999999996,-0.11766769999999999,0.103258935,-0.099714549,-1.610272919,-1.217994179,0.428811974,1.304524708,-4.236303406,-3.520186157,-4.116255905,-4.384792305,-3.820021767,-5.340260895,-5.111732891,-2.645466687,-12.64435863494873,-9.797170639038086,-10.849048614501953,-10.120643615722656,-11.265315055847168 -1812,1812,E119M,0.07336774,0.007963481,0.047043215,0.044637252,-1.63992501,0.022757912999999998,0.020850139,0.12588534099999998,-0.328727576,0.09085733,-0.07493036900000001,0.10622843400000001,-0.012142004,0.024485497000000002,0.064789006,-1.695655313,-1.584194706,0.232308177,1.297717247,-7.126239142,-5.726748512,-6.319437027,-8.479501549,-7.277422256,-7.828086365,-6.72140024,-5.418231904,-12.719914436340332,-10.229480743408203,-12.342960357666016,-9.871447563171387,-12.944226264953613 -1813,1813,E119L,-0.013107576000000001,-0.028284042000000002,-0.773277697,-1.782227899,-2.748624492,0.009621956,-0.0033194640000000003,-0.022895687999999997,0.069983826,-0.018177868,-0.038390216,-0.582917849,-0.963637544,-1.752131628,-1.81232417,-2.625766636,-2.8714823469999997,1.8875736,0.8916013690000001,-8.111070361,-6.127335304,-6.84986721,-8.990299294,-8.466697754,-10.12115224,-7.2462287860000005,-5.58848306,-13.61591911315918,-10.816330909729004,-12.612545013427734,-10.18648910522461,-13.427241325378418 -1814,1814,E119N,-0.120584419,-0.039268838,-0.073064934,-0.00890441,-0.608434947,0.102338391,0.038506997,-0.279675834,-0.024991687000000002,-0.009026778000000001,-0.069510897,0.012504633999999999,-0.15863450199999998,-0.002215165,-0.015593653999999998,-0.36396681200000003,-0.852903082,0.770655303,1.5215985330000001,-5.480216544,-4.872452866000001,-5.234579094,-5.839473305,-5.04298188,-6.411595573,-6.222045655,-2.562557682,-10.938963890075684,-8.129928588867188,-10.700202941894531,-8.815993309020996,-11.161493301391602 -1815,1815,E119Q,0.067221893,-0.016648171,-0.021277993999999998,-0.024171667999999997,-0.055457407,0.033561602,0.072002661,0.062441124,0.008176675999999999,0.011670804,-0.044967146,0.048767262,-0.09132325,-0.026441495,-0.021901841000000002,-0.049598853,-0.061315960999999995,1.198641987,2.368205152,-1.638491614,-1.0980145190000001,-1.812986115,-1.5868096919999999,-1.64097541,-2.053672333,-3.748466943,-1.439937795,-8.200528144836426,-6.339210510253906,-7.336531639099121,-6.631906509399414,-8.482189178466797 -1816,1816,E119P,-0.046665984,-1.0562393490000002,-1.78039466,-2.052073253,-2.8951336789999997,0.058644552999999995,0.065300174,-0.158632141,0.233915103,-1.0529775909999999,-1.059501106,-1.941120384,-1.6196689359999998,-2.081458035,-2.022688471,-3.085426811,-2.7048405460000002,2.9947873360000004,0.929476379,-8.891905582,-7.694458282,-8.528895508,-9.58120414,-9.023863731,-9.631106247,-9.71395341,-9.407631909,-17.008026123046875,-14.75012493133545,-14.223163604736328,-12.789633750915527,-16.457408905029297 -1817,1817,E119S,-0.011048661000000001,-0.015268338000000001,0.013415975,0.032591402,-0.36466954100000004,0.080931762,0.072550667,-0.094647989,0.117821774,0.020995642000000002,-0.051532317,0.055726628,-0.028894677999999997,0.014100915,0.051081888,-0.270566868,-0.458772213,1.340198313,1.951727311,-4.23065016,-3.454488388,-4.408773605,-5.382678696,-2.7464368739999996,-5.160873238,-5.393249125,-3.127076967,-11.37700366973877,-8.801416397094727,-9.86653995513916,-8.588553428649902,-11.70192813873291 -1818,1818,E119R,0.10725186800000001,-0.026716762999999998,-0.040606919,-0.30301448,-1.7349685469999998,0.084484672,0.041286252999999995,0.173217482,0.040687088999999996,0.000950152,-0.054383677000000005,0.033731002999999996,-0.11494484099999999,-0.118437624,-0.48759133600000004,-1.96699974,-1.5029373540000002,1.109945065,1.320443283,-4.307724948,-3.488356247,-4.966280853,-2.899113945,-5.384098732000001,-4.800774963,-5.814927518999999,-3.0035188039999996,-13.664901733398438,-11.236997604370117,-12.302741050720215,-11.007884979248047,-13.70635986328125 -1819,1819,E119T,-0.043812727999999995,-0.050105737000000004,-0.034074847000000005,-0.439345945,-1.904197339,-0.00197845,0.025871339,-0.113496795,0.10984029,0.0024755520000000002,-0.102687025,0.017552782,-0.085702475,-0.19099163600000002,-0.687700254,-1.9179554,-1.8904392780000001,1.164230687,1.326061778,-4.774644252,-3.326310326,-4.511568993,-6.240483215,-4.002391434,-5.792467293,-6.252612284,-2.49204337,-11.573917388916016,-8.16322135925293,-10.66916561126709,-9.09109878540039,-11.669427871704102 -1820,1820,E119W,0.114758286,-0.055911817999999995,-1.11421463,-1.8799838780000002,-2.695865472,0.031206706,0.19320356800000002,0.036313002999999996,0.052595816,0.099543384,-0.211367019,-1.012098821,-1.216330439,-1.916799439,-1.8431683159999999,-2.966525705,-2.425205238,2.187481187,0.924705605,-9.301594263,-8.048908127,-8.285021011,-9.650076889,-10.65793174,-9.866033546,-7.093385975,-4.00566663,-16.754108428955078,-12.838226318359375,-16.059886932373047,-13.556341171264648,-16.76280403137207 -1821,1821,E119V,0.054693492999999996,-0.147576713,-1.4574484109999999,-1.58575783,-2.23644673,0.041332488,0.038918066,0.07046892,0.03300026,-0.07929504,-0.215858386,-1.529722161,-1.385174661,-1.9102685719999999,-1.261247088,-2.922206277,-1.5506871830000002,2.673647093,1.094959223,-6.592684632999999,-4.885019386000001,-6.064036591,-7.462946396,-6.603810814,-7.947609977999999,-6.951979112,-4.502924053,-12.293725967407227,-10.790000915527344,-12.312023162841797,-10.184076309204102,-12.501503944396973 -1822,1822,E119Y,0.007885101,-0.011861743999999999,-0.574234846,-1.4032725330000002,-2.12499127,0.061426217000000005,0.107448004,-0.09167780199999999,0.183644397,0.035115863,-0.058839351,-0.37787158,-0.7705981120000001,-1.402478497,-1.4040665680000002,-2.3942128169999997,-1.8557697219999998,2.199158356,1.263602691,-8.516695237999999,-7.010555946,-7.148606316,-9.521410561,-8.796994949,-10.10590842,-6.916279053999999,-3.767088222,-15.201719284057617,-11.522011756896973,-14.08666706085205,-11.90280818939209,-14.354508399963379 -1823,1823,L120A,0.02299752,-0.013729086000000001,0.010712556000000002,-0.06949089,-1.656683027,0.028566243999999998,-0.048126712,0.09412175099999999,-0.28792695,0.00031612599999999996,-0.027774298,-0.034713744,0.056138855,-0.063100748,-0.075881031,-1.722725199,-1.590640854,0.756881033,1.3128743520000001,-6.779326322999999,-10.21371678,-5.063780914,-5.985266387999999,-5.482024605,-7.1518429260000005,-5.5046985070000005,-2.640429182,-9.584270477294922,-11.438726425170898,-7.733077049255371,-7.435680389404297,-5.121904373168945 -1824,1824,L120C,-0.101415136,-0.035107395,0.015466852,-0.218310167,-1.956852199,0.068187271,-0.10916250599999999,-0.093667766,-0.157928415,-0.024750926,-0.045463863,-0.029902821,0.060836525,-0.096890654,-0.339729679,-1.8271588619999999,-2.086545535,0.838262957,1.3108779179999999,-9.26758956,-11.820203300000001,-7.9149526670000006,-10.4553448,-8.57997422,-7.567472816,-8.546422005,-5.314053546,-11.657893180847168,-14.933221817016602,-9.714557647705078,-8.45962905883789,-11.662799835205078 -1825,1825,L120E,0.06409161099999999,-0.827785131,-1.827650557,-2.3347754259999998,-2.6890916860000003,0.003009156,-0.03647872,0.164661942,0.113943352,-0.79526412,-0.860306142,-1.513840221,-2.141460893,-2.435134096,-2.234416756,-2.669124015,-2.709059356,2.276898686,0.5246398,-12.82088511,-15.08617767,-10.8400903,-13.770397899999999,-11.97115508,-12.43660458,-11.01015823,-10.46629924,-16.120668411254883,-17.1513671875,-14.186906814575195,-15.054365158081055,-13.996853828430176 -1826,1826,L120D,0.074830658,-1.28167561,-1.706435665,-2.0423491940000003,-2.635226081,0.021659634,0.0373184,0.112342916,-0.099936468,-1.115962242,-1.4473889780000002,-1.9853575980000002,-1.427513732,-2.342380042,-1.742318345,-2.576369962,-2.6940822,2.140236116,0.05332438,-12.27562912,-14.31069049,-10.3235269,-13.42916042,-10.806689,-12.50807878,-10.13489741,-7.910881902000001,-17.657100677490234,-18.71812629699707,-15.454977035522461,-11.520051002502441,-15.902856826782227 -1827,1827,L120G,0.032231806,-0.057572306,-0.911409424,-1.7300821869999998,-2.8045577510000004,0.038178103,-0.005341756,0.06980536799999999,-0.052163685999999994,-0.043639088,-0.071505523,-0.86985331,-0.952965538,-1.70103253,-1.7591318440000001,-2.4210985469999997,-3.1880169539999996,2.705890477,1.431829424,-12.25745872,-14.95840295,-9.967017372,-13.12923133,-10.53961652,-12.69302542,-9.730856201,-7.2385577329999995,-14.007676124572754,-17.345476150512695,-13.090617179870605,-12.279277801513672,-11.721524238586426 -1828,1828,L120F,-0.143083964,-0.070924935,-0.036593797000000004,-1.320975046,-1.8853995069999998,0.014019566,-0.072724628,-0.21344329899999998,-0.176324814,-0.08573392699999999,-0.056115942,-0.061889319000000005,-0.011298275,-1.351385529,-1.2905645620000001,-2.138217417,-1.632581597,2.532095335,1.6166678159999999,-7.474878329,-8.921046371000001,-5.998237221,-8.518871803,-7.169236961,-6.76699929,-7.813022942999999,-5.475027282,-11.73192310333252,-12.522974014282227,-10.463072776794434,-11.26069450378418,-10.42776870727539 -1829,1829,L120I,-0.093062184,-0.033820483,-0.033177166,0.006083796,-1.593683033,0.030188813999999998,-0.018884115,-0.167240253,0.025002269,-0.018894333,-0.048746633,-0.016407917,-0.049946414,-0.010497431000000002,0.022665022000000003,-1.856210659,-1.331155407,0.9061646990000001,1.31388891,-4.420372446,-2.762978355,-4.785669693,-5.967418137,-3.733488632,-4.852307411,-5.797769323,-2.278558895,-7.314653396606445,-7.491559028625488,-5.54625129699707,-7.353189468383789,-4.756369590759277 -1830,1830,L120H,-0.022094599,-0.061687775,-0.096858537,-1.5221624669999998,-2.436765693,0.053375293,-0.06435376,0.020164563,-0.16688325699999998,-0.030332187000000004,-0.09304336199999999,-0.098367396,-0.095349677,-1.575365158,-1.468959776,-2.5497177669999997,-2.323813618,2.492908042,1.454956032,-9.823517642,-12.09361266,-7.385449371,-12.39152749,-9.390818474,-7.856180222000001,-8.445615887999999,-5.994888232999999,-15.848073959350586,-15.941497802734375,-14.746461868286133,-14.725667953491211,-13.85223388671875 -1831,1831,L120K,-0.071753928,-1.041858582,-2.090939601,-2.378398123,-2.7327143830000002,-0.01130161,-0.041366793,-0.10214106199999999,-0.577057722,-0.984354745,-1.099362419,-2.28947867,-1.8924005309999998,-2.470409856,-2.286386389,-2.7043997760000003,-2.76102899,2.003800039,-0.19557209,-12.30462457,-14.22532285,-10.445853,-13.90957055,-11.00230421,-11.94007227,-11.01015823,-10.46629924,-16.782047271728516,-17.93805503845215,-17.2476806640625,-16.144865036010742,-16.031238555908203 -1832,1832,L120M,-0.035090458,-0.08743104199999999,0.020338493,-0.014890736000000002,-0.31533879,0.035218895,-0.009748616,-0.060432299,-0.12341756300000001,-0.031796822,-0.143065262,-0.0047638,0.045440786,-0.08853473,0.058753259,-0.30009818,-0.330579399,1.645720261,2.145514509,-4.683491951000001,-6.013356056,-4.850749702,-5.353772354,-3.6519196010000003,-3.547662041,-7.099233077999999,-3.770962523,-8.436384201049805,-10.108607292175293,-7.238473892211914,-7.9084343910217285,-7.064077854156494 -1833,1833,L120N,-0.166891696,-0.074843088,-1.083139164,-1.921642949,-2.926474207,0.008922233,-0.07400726,-0.259776132,0.268040318,-0.092699934,-0.056986242,-1.117983163,-1.048295164,-2.0392770380000003,-1.804008859,-2.8753269489999997,-2.977621464,2.240315851,0.8817686379999999,-12.29841585,-14.57026831,-10.18499422,-14.13408275,-11.48103595,-11.12169802,-11.01015823,-10.46629924,-14.661482810974121,-16.37605857849121,-14.451532363891602,-11.653247833251953,-12.696393966674805 -1834,1834,L120Q,-0.104077028,-0.07492291,-0.694368538,-1.668685239,-2.673516497,0.036116577999999996,-0.118269995,-0.089884061,-0.232562033,-0.062568608,-0.087277211,-0.61136972,-0.777367355,-1.5749526569999999,-1.76241782,-2.712032564,-2.635000429,2.004604547,1.009126636,-11.75469424,-14.05481695,-10.04402764,-13.54320495,-10.36904958,-10.76237208,-11.01015823,-10.46629924,-13.432991981506348,-14.170072555541992,-13.627243995666504,-14.13665771484375,-13.009159088134766 -1835,1835,L120P,-0.20267906,-1.448452995,-1.73058359,-2.141294259,-2.779291773,0.026533965,-0.083219994,-0.322138125,-0.00041981099999999997,-1.5724385159999998,-1.324467473,-1.8996125819999998,-1.561554597,-2.089687147,-2.192901371,-2.67355563,-2.8850279160000003,-0.17015593,-0.9797462109999999,-12.81945266,-14.889889499999999,-11.15148304,-13.60405658,-11.79561839,-12.65621578,-11.01015823,-10.46629924,-17.14543342590332,-16.08820915222168,-16.09088706970215,-13.526025772094727,-12.495610237121582 -1836,1836,L120S,-0.129646444,-0.006451923,-0.14635512,-1.459169986,-2.488623444,0.041843557999999996,0.00296084,-0.262253727,-0.11031850300000001,0.013191378,-0.026095224,-0.08511278800000001,-0.207597452,-1.344003575,-1.5743363959999999,-2.2051642069999997,-2.77208268,2.281240774,1.4301092180000001,-10.49130075,-12.89355479,-8.259694817,-11.0396804,-9.542776299,-10.72079745,-8.628326632,-6.8715029979999995,-12.434784889221191,-15.588775634765625,-12.522318840026855,-10.0748291015625,-10.88463020324707 -1837,1837,L120R,0.025515432,-1.564780399,-1.7247857919999998,-2.0466849590000002,-2.676454953,0.024367838,-0.014921218,0.065952082,-0.109276494,-1.815593525,-1.313967272,-1.7405062080000002,-1.709065375,-2.018347407,-2.07502251,-2.854397318,-2.498512588,-0.034350843,-1.08917561,-12.20881358,-14.399301999999999,-10.15873238,-14.62317763,-11.14048022,-10.72237565,-11.00429669,-10.44368496,-17.668834686279297,-16.929935455322266,-16.53323745727539,-17.119752883911133,-16.30641746520996 -1838,1838,L120T,-0.148518615,-0.054859969,-0.050781527,-1.236380863,-2.41338899,0.045855872,-0.024277875,-0.272759355,0.06846796299999999,-0.057697217,-0.05202272,-0.045169590999999995,-0.056393462000000005,-1.063963954,-1.408797771,-2.234822287,-2.591955693,2.10986661,1.3969355490000002,-9.810568321,-11.57798013,-8.117021362000001,-10.34708717,-9.033279045,-9.977473892,-8.627261715,-3.609139158,-11.392451286315918,-13.234597206115723,-10.377378463745117,-9.137720108032227,-9.125767707824707 -1839,1839,L120W,-0.073859018,-1.120271313,-1.674850023,-1.9394297999999999,-2.643231062,-0.081661496,-0.043160305,-0.10455773,-0.099936468,-1.2552977459999999,-0.985244879,-1.8614516669999999,-1.488248379,-2.042382852,-1.8364767469999999,-3.1794627589999997,-2.106999365,3.274460714,1.06544634,-10.93678209,-12.20441442,-9.316925919,-13.09140387,-10.46100502,-9.610161217,-9.598967032000001,-7.238559795,-15.363356590270996,-16.535884857177734,-13.914366722106934,-15.893741607666016,-14.459510803222656 -1840,1840,L120V,0.022592211,-0.034971125,-0.033748045,-0.749995458,-1.783373826,0.019700017,-0.02112445,0.06630887099999999,-0.022639365,-0.03478392,-0.035158329,-0.067708891,0.00021280099999999998,-0.437509459,-1.062481456,-1.776018249,-1.790729402,1.68802588,1.4382670359999998,-6.121450857999999,-5.411335167000001,-5.318412331,-7.063089249,-5.965684044,-6.848733498,-6.275142444,-2.403078808,-8.215673446655273,-9.866158485412598,-7.188154220581055,-8.113303184509277,-4.72805118560791 -1841,1841,L120Y,-0.19271619,-0.067237223,-0.976410861,-2.069672038,-2.901109553,-0.035069896,-0.138149458,-0.24728292100000002,0.094638197,-0.081807966,-0.052666479,-0.987292098,-0.9655296240000001,-2.196252007,-1.943092069,-2.907363181,-2.894855924,1.9427055469999999,0.685554087,-9.252887592999999,-10.44423698,-7.110301193,-12.03281886,-8.863742226,-7.813338707000001,-8.984130329,-5.543246839,-14.59897232055664,-16.031024932861328,-12.867777824401855,-14.579460144042969,-14.036079406738281 -1842,1842,C121A,0.08904931599999999,-0.051104409,-0.016551268,-0.03542283,-1.3671009619999999,0.113933064,-0.060064549,0.238163181,-0.05996154,-0.029643719,-0.072565098,-0.059738022,0.026635486,-0.00020346400000000002,-0.070642195,-1.111149637,-1.623052287,0.7699435659999999,1.354085498,-9.043801167,-7.44146653,-8.434157897999999,-12.06368692,-7.945701004,-9.333993485,-6.076570661,-0.423668018,-9.3427095413208,-7.807577133178711,-7.150782585144043,-9.25570011138916,-8.370688438415527 -1843,1843,C121E,-0.38730118700000005,-0.5574972420000001,-1.6747039590000001,-2.1232695969999997,-3.29997929,0.138492817,-0.099225645,-0.675376729,-0.046996563,-0.43425619200000004,-0.6807382909999999,-1.66993764,-1.6794702769999998,-2.068476263,-2.178062931,-3.046647825,-3.553310754,2.781318508,1.0109896520000001,-14.72908192,-13.00862576,-13.79711082,-18.29942474,-14.82673293,-13.71351537,-10.09918734,-7.014622481,-16.032238006591797,-14.163881301879883,-12.63410758972168,-16.37054443359375,-13.092371940612793 -1844,1844,C121D,0.21479204899999998,-1.165109903,-1.696132149,-1.9400130530000002,-2.63960149,0.199178537,0.013463566000000001,0.416120531,-0.198264238,-1.331960468,-0.998259338,-1.708537425,-1.6837268719999998,-1.764653367,-2.115372738,-2.7428249289999997,-2.53637805,3.9322031760000002,1.751915249,-15.418200699999998,-13.17122884,-15.8404536,-18.83912002,-14.96226876,-14.27793228,-11.08138346,-9.465434804,-15.897716522216797,-12.888298988342285,-11.893725395202637,-15.524188995361328,-14.4320068359375 -1845,1845,C121G,-0.241937707,0.013519752,-0.019227142,-0.77877055,-1.7945430709999999,0.150088741,-0.05195228,-0.43192313299999996,-0.102299371,-0.001209022,0.028248525,-0.071658556,0.033204272,-0.33901008899999996,-1.2185310109999998,-1.884931691,-1.704154451,1.505712542,1.3758996559999999,-11.54551561,-10.141869999999999,-11.1756465,-14.22047592,-11.23001231,-10.95957333,-7.370933,-4.026302292,-10.15992546081543,-9.826658248901367,-8.804643630981445,-12.482705116271973,-10.372320175170898 -1846,1846,C121F,-0.074983199,-0.58500169,-1.54289959,-2.627401113,-2.977504548,0.11021342199999999,0.026360593999999998,-0.17632699100000002,-0.007488021,-0.454548041,-0.7154553379999999,-1.6776977240000002,-1.408101456,-2.636903653,-2.617898572,-2.916105211,-3.038903885,1.4543412180000002,0.077050227,-11.13681386,-11.91545425,-10.32494781,-11.68280393,-11.364832400000001,-10.39603092,-8.191645538,-4.53904156,-12.791831970214844,-10.872604370117188,-11.016169548034668,-13.926010131835938,-11.275263786315918 -1847,1847,C121I,0.259461097,0.00710009,0.032175185,-0.656352659,-1.655882633,0.033758197999999996,0.032520903,0.48640129,-0.323202975,0.045457874,-0.031257694,0.005090409000000001,0.05925996099999999,-0.292501931,-1.020203386,-1.8705565659999999,-1.4412086990000001,1.383009406,1.356589223,-11.24472802,-10.51708639,-10.29750864,-15.45507884,-10.97010925,-8.983856979,-6.147742755,-1.1326044309999999,-12.162301063537598,-11.318587303161621,-10.05422306060791,-12.371270179748535,-10.682765007019043 -1848,1848,C121H,0.245762969,-1.008258141,-1.989788875,-2.160605761,-2.933258216,0.157037449,0.054128558,0.437397379,-0.077379192,-1.204210754,-0.812305527,-1.8383520130000002,-2.141225737,-2.049369915,-2.271841607,-3.173669513,-2.692846919,3.104662032,0.953945461,-13.60248731,-12.85469775,-13.90513334,-14.56083838,-14.83281078,-11.858956300000001,-11.08138346,-9.465434804,-16.530820846557617,-14.196128845214844,-12.426384925842285,-16.001638412475586,-13.719396591186523 -1849,1849,C121K,-0.34705847,-1.7639901869999999,-2.032630988,-2.0586476069999997,-3.1473116689999996,0.10340280800000001,0.001442819,-0.6955597590000001,0.055665779000000006,-2.018135274,-1.5098451000000002,-2.248584195,-1.81667778,-2.3047001369999998,-1.812595076,-2.8849316910000002,-3.409691647,-0.7667220229999999,-1.109007334,-14.91392062,-13.02578659,-14.68414422,-17.83433099,-15.31583733,-13.70950399,-11.08138346,-9.465434804,-17.271770477294922,-17.1907901763916,-15.545853614807129,-17.185707092285156,-14.633770942687988 -1850,1850,C121M,-0.357090377,-0.014821632,-0.021657572000000003,-0.031270103,-1.306918993,0.047801085,-0.015693186,-0.698487567,-0.113943352,-0.047996465999999995,0.018353202,-0.09943939,0.056124247,-0.037940453,-0.024599752000000003,-0.9104280779999999,-1.703409907,1.0730850140000001,1.4439148419999999,-11.3720801,-10.82752172,-10.36049347,-15.44360423,-10.984762400000001,-9.244018668999999,-6.984676546,-2.0005924530000003,-12.032827377319336,-11.814805030822754,-11.288816452026367,-13.250353813171387,-11.25216007232666 -1851,1851,C121L,-0.274144408,-0.00364386,-0.028326804,-0.153440919,-1.6218186190000001,0.05121568,-0.030056167999999998,-0.518232647,-0.028636553999999998,-0.060252387000000004,0.052964667,-0.131614388,0.07496078099999999,-0.054391052,-0.252490786,-1.838188287,-1.40544895,0.9615390690000001,1.31623328,-9.27140817,-8.954845261000001,-9.071960662999999,-13.2588564,-9.148336562999999,-5.923041962,-5.586063383,-0.280640812,-11.102672576904297,-11.077606201171875,-10.5520658493042,-12.418156623840332,-10.421259880065918 -1852,1852,C121N,0.067136036,-0.172269063,-1.523141251,-2.145503129,-2.918155585,0.158242551,0.023355083999999998,0.11091698800000001,-0.101354225,-0.072471825,-0.2720663,-1.5182057269999998,-1.528076774,-1.933343611,-2.3576626469999997,-3.0576432089999996,-2.77866796,0.8861469040000001,0.052084602,-11.77903896,-9.782613403,-11.61645774,-14.00282105,-11.88408625,-11.60921635,-8.49840483,-4.7841468019999995,-13.052279472351074,-11.237831115722656,-10.577250480651855,-13.16309928894043,-12.64112663269043 -1853,1853,C121Q,-0.281436902,-0.010642893,-1.033263262,-1.9762299509999999,-2.763864018,0.146684539,0.011581033999999999,-0.574454837,-0.05154419,-0.113600046,0.092314261,-0.946108959,-1.120417565,-2.051442923,-1.9010169780000001,-2.029614486,-3.49811355,3.893253459,2.469946035,-13.86988745,-11.68733726,-14.08540994,-17.3102149,-13.91311222,-12.35336292,-9.145917698,-5.44339499,-15.477327346801758,-13.828680038452148,-12.823518753051758,-14.92721176147461,-13.13630485534668 -1854,1854,C121P,0.014326252,-1.1707316540000001,-1.435815141,-1.895162396,-3.318329849,0.148917406,0.004487110999999999,0.024165392999999997,0.007760084,-1.5589726919999998,-0.782490615,-1.92564136,-0.945988921,-1.9594809069999999,-1.830843884,-2.93765247,-3.699007228,-0.425027163,-1.007267713,-15.58216019,-13.98711913,-15.27742196,-18.6552596,-15.16515134,-14.82584893,-11.04661982,-9.256621153,-18.030344009399414,-15.794187545776367,-15.168821334838867,-16.330188751220703,-15.455543518066406 -1855,1855,C121S,-0.004262668,-0.032590156,-0.061782751,-1.129522757,-2.140735839,0.13235694,-0.020355916,0.011830581000000001,-0.021919967000000002,-0.045099001,-0.02008131,-0.128704409,0.005138907,-0.887250888,-1.371794625,-2.196415669,-2.085056009,2.048854253,1.408475585,-8.284762036,-7.8530419160000005,-7.194481049,-10.08126069,-7.365001717,-8.930024811000001,-5.40203406,-2.4142472230000003,-7.316211700439453,-6.872206687927246,-7.690009117126465,-9.724889755249023,-8.367953300476074 -1856,1856,C121R,-0.122144979,-1.3863653040000001,-1.743061725,-1.556369895,-2.98414135,0.18495450100000002,0.006456412,-0.25074637,-0.099932638,-1.588786801,-1.1839438070000001,-1.911989776,-1.574133674,-1.875351664,-1.237388126,-2.967466579,-3.00081612,-0.17867688699999998,-1.084714557,-15.01716115,-12.8946364,-15.36389944,-18.2371652,-15.125829800000002,-13.46427489,-11.07550393,-9.444781489,-14.76447582244873,-14.108516693115234,-12.70713996887207,-16.247697830200195,-12.308845520019531 -1857,1857,C121T,0.087605024,-0.010107627,-0.629777312,-1.894506356,-2.611475847,0.13991848,-0.007830071999999999,0.18304011899999997,-0.0027929,-0.01619398,-0.004021274,-0.510628628,-0.748925996,-1.654198342,-2.13481437,-2.570221998,-2.6527296959999997,1.808952273,0.8969425940000001,-10.81346519,-9.291862457,-10.28919936,-13.52349158,-10.45933512,-10.50343742,-7.443044345,-3.642841996,-9.991416931152344,-8.980653762817383,-9.07808780670166,-10.251564025878906,-10.028600692749023 -1858,1858,C121W,-0.31389370699999997,-1.342967234,-1.840516085,-1.936758155,-2.747270968,0.139367785,-0.05045695,-0.577330463,-0.100440882,-1.635086821,-1.050847647,-2.3426569969999997,-1.338375173,-2.00083293,-1.87268338,-2.501883238,-2.992658697,-0.052308379,-1.052172302,-14.70164459,-13.964830599999999,-14.65707964,-16.89547982,-14.73827728,-13.25255561,-11.08138346,-9.465434804,-13.589725494384766,-12.039241790771484,-10.53798770904541,-16.43331527709961,-13.351675987243652 -1859,1859,C121V,-0.158676462,0.024574349,0.011321338,-1.439136199,-2.614484462,0.10073091699999999,0.039221286,-0.35657421,-0.032273306,-0.026572017000000003,0.07572071400000001,-0.05240148,0.075044156,-1.3436716380000002,-1.53460076,-2.452176969,-2.776791955,0.784408654,0.7245042079999999,-12.54662394,-10.8514162,-12.78869063,-16.4584889,-12.49167668,-10.14284729,-6.27722098,-1.625096725,-11.785143852233887,-10.86066722869873,-9.299456596374512,-11.581779479980469,-10.811118125915527 -1860,1860,C121Y,0.047350641,-1.318099174,-2.075009417,-2.201848718,-2.941027778,0.14922196599999998,0.077393558,0.017307723,-0.210853365,-1.52309098,-1.113107367,-1.846293955,-2.3037248790000002,-1.9693566869999999,-2.4343407480000003,-3.026709495,-2.855346061,3.549455075,1.144476971,-11.52922771,-12.26616351,-11.2321983,-11.579736500000001,-11.9909801,-10.57706013,-9.358709401,-5.253733566,-14.868734359741211,-10.73538875579834,-11.22462272644043,-13.255775451660156,-10.844175338745117 -1861,1861,S122A,0.24178902800000002,0.014265926000000002,0.014197302,0.017726278,-0.020963348,-0.021860242000000002,-0.07727714299999999,0.560855199,,0.049056704000000007,-0.020524853,-0.0014922720000000002,0.029886876,-0.002413747,0.037866303,-0.022953799,-0.018972897,1.295753468,2.63461228,-0.468063541,-0.9094229970000001,-0.35873782299999996,0.332229744,-1.009562325,-0.394824303,-2.312838131,1.1383991759999998,-1.4281818866729736,-4.047162055969238,-3.2339794635772705,-2.2778589725494385,-2.7274515628814697 -1862,1862,S122C,0.295501434,-0.016514933,-0.025305624,-0.020250367,-0.640035726,0.04877594,0.162551637,0.428451231,,-0.022536422999999996,-0.010493443,-0.029259877000000004,-0.021351371,-0.000521753,-0.03997898,-0.5146321660000001,-0.765439285,0.867855422,1.4913849430000001,-5.971429757999999,-5.576058472000001,-7.012711632,-6.079024307,-6.869572586,-4.319781792,-6.71498637,-2.967315985,-8.297958374023438,-9.25275993347168,-8.968856811523438,-7.767134666442871,-8.527301788330078 -1863,1863,S122E,-0.17085546,0.006414537,-0.021761887999999997,0.026649233999999997,0.036991756,-0.014261548,0.067474093,-0.409185013,,0.000935148,0.011893925,-0.06262572599999999,0.01910195,0.035329037,0.017969431,-0.006971860999999999,0.080955373,1.129761546,2.579313822,-0.20031553800000002,-0.6578881839999999,-0.125178635,1.1486866759999999,-0.790706474,-0.576491074,-1.6956628390000001,1.761568381,-2.3166913986206055,-4.303103446960449,-2.8701679706573486,-0.05368971824645996,0.01378774642944336 -1864,1864,S122D,-0.27560054100000003,0.01840403,0.019735145,0.083809573,0.050177167,0.032125816,-0.018137933999999998,-0.533063148,,0.032539446,0.004268613,-0.0023338910000000003,0.04180418,0.078320838,0.089298308,0.060110454,0.040243878999999996,1.094874774,2.7930978239999997,-0.546352617,-1.183285957,0.100588707,-0.077918282,-1.226565208,-0.344582344,-2.5526485,1.0194325370000001,-2.6210412979125977,-6.106041431427002,-1.268467903137207,-1.2403504848480225,-1.1372008323669434 -1865,1865,S122G,0.267659731,-0.0017200289999999999,0.001057512,0.009623286,0.025668662000000002,-0.0037724390000000003,0.061338394000000004,0.47398106799999995,,0.039880992000000004,-0.043321049,0.009261048000000001,-0.007146025,0.036787454,-0.017540883,0.019111992,0.032225332,1.129499537,2.631264114,-4.272196315,-4.309300751,-4.406683655,-3.9191650310000004,-3.353578148,-5.37225399,-4.2684291530000005,-0.9665337909999999,-4.570687294006348,-6.008709907531738,-4.522866249084473,-5.3473310470581055,-5.483845233917236 -1866,1866,S122F,0.223634311,-0.058547854,-0.057664327,-0.08606246099999999,-0.15904294300000002,-0.029089707000000003,-0.063093786,0.510362407,,0.047415730999999996,-0.164511439,0.049316847000000004,-0.164645501,0.030378638,-0.20250355899999997,-0.043411736,-0.274674149,1.197729864,2.450691772,-5.070621295,-5.519624107,-5.394254601,-4.364059868,-4.901599686,-5.173568213999999,-4.559770288999999,-1.210799875,-6.184329032897949,-9.8704833984375,-9.75497055053711,-4.690210342407227,-6.847223281860352 -1867,1867,S122I,0.38333309299999996,-0.034974694,0.015222868999999998,-0.136142781,-0.154171419,-0.031686699,0.067576124,0.6990900609999999,,0.040318451,-0.110267839,-0.008129338,0.038575076,-0.042909855999999996,-0.229375705,-0.129169277,-0.179173561,1.3237531679999999,2.196593886,-6.495264589,-6.186572525,-7.465992767,-6.7271576,-6.349600517000001,-5.746999535,-4.964815043,-1.6341482790000001,-4.9519944190979,-9.044189453125,-8.580131530761719,-4.944485664367676,-6.318672180175781 -1868,1868,S122H,-0.034118307,0.045482842999999995,0.017067295,-0.012360421000000002,0.011127575,0.019762977,0.049651800999999995,-0.117888415,,-0.022894287000000003,0.113859973,-0.041038363,0.075172952,-0.011838168,-0.012882673,-0.023634075,0.045889224000000006,1.327193941,2.559648193,-1.4631342219999999,-1.788205711,-1.1143837509999999,-1.216043495,-1.2692658540000001,-1.9277723009999999,-2.99903092,-0.20073053800000001,-4.444431304931641,-6.464240550994873,-5.327873706817627,-1.8432903289794922,-4.707548141479492 -1869,1869,S122K,0.458420799,-0.134713405,-0.088577747,-0.036015889,-0.070357872,0.007972893,0.112725785,0.804115813,,-0.015252393999999999,-0.254174415,-0.018578482,-0.158577011,-0.007466321,-0.064565457,-0.044879388,-0.095836355,1.359140214,2.486134582,-2.184460385,-3.358229805,-2.60639222,-1.932221634,-1.63794754,-1.3875107269999998,-3.086993337,0.368000111,-4.185833930969238,-6.01645040512085,-6.914691925048828,-3.9563310146331787,-5.394211769104004 -1870,1870,S122M,0.211697407,-0.315487525,-0.11627018,-0.19636842899999998,-0.229901572,-0.0029971159999999998,-0.480901039,0.9042958520000001,,-0.059380222,-0.5715948270000001,-0.030298846,-0.202241513,0.012730108,-0.405466965,-0.10933720599999999,-0.350465937,1.33716199,2.267876502,-6.276913095,-6.25337159,-5.806894333,-8.444610039,-5.62410144,-5.255588073999999,-4.878974259,-0.615874059,-4.536820411682129,-7.484930038452148,-7.776035785675049,-4.045488357543945,-6.4053802490234375 -1871,1871,S122L,0.331875076,-0.000562799,0.004137846,-0.026732442999999998,-0.00930864,-0.043199318,0.072995392,0.59075476,,0.0007785310000000001,-0.001904128,0.007673787,0.000601905,0.027049215,-0.0805141,-0.030728976,0.012111697,1.243379167,2.524836693,-4.752742255,-4.374715561,-3.819661934,-7.101070762999999,-5.34078421,-3.127478806,-4.162259458,-0.524134013,-3.6907482147216797,-7.087789535522461,-7.427501678466797,-4.035280227661133,-5.1164984703063965 -1872,1872,S122N,0.320454327,-0.003168969,0.023173238999999998,0.043213386,0.028354137,-0.010935186000000001,0.016423602,0.624485052,,-0.012890945,0.006553007,0.042533507000000005,0.00381297,0.019973674,0.066453097,0.021332322999999997,0.03537595,1.227535504,2.729066012,-2.117115833,-2.690763145,-2.2265608830000003,-2.459575127,-1.9188783040000001,-1.289801704,-3.620829591,-0.718997155,-3.930882453918457,-6.639511585235596,-4.612437725067139,-2.718116283416748,-3.904496908187866 -1873,1873,S122Q,0.24952331100000003,-0.015866081,-0.009192786,-0.053999738,0.031705227999999995,-0.043940702000000005,0.06801950799999999,0.43102711299999996,,-0.017252361,-0.014479801,0.00291218,-0.021297751,0.0063082469999999995,-0.11430772300000001,-0.0063775459999999996,0.069788001,1.266443155,2.720386773,-2.060977135,-1.9704271469999999,-1.312899223,-2.3309226990000003,-2.471541809,-2.219094795,-3.1920795039999996,0.193925428,-2.57722806930542,-5.526610851287842,-4.709824562072754,-1.7478549480438232,-3.032421827316284 -1874,1874,S122P,0.11809733,0.012619677,-0.23945133100000002,-0.88923865,-1.137558841,0.035295834,0.040650184,0.195544475,,0.00224526,0.022994092999999997,-0.41800113,-0.060901530999999995,-1.611457371,-0.167019928,-2.223441825,-0.051675856,2.53270911,1.4797551690000001,-8.071793167000001,-8.280587357,-7.844758499,-8.26466362,-8.242219887000001,-7.726736473,-8.595015477,-6.9941420889999995,-9.343485832214355,-13.993841171264648,-11.043482780456543,-9.165559768676758,-11.522787094116211 -1875,1875,S122R,-0.003072379,0.020958215,0.015684232,0.020640951,0.004943197,-0.008013905,0.057109800999999995,-0.063254559,,-0.022662572000000002,0.064579001,-0.0027313890000000003,0.034099852,0.012808469,0.028473432000000003,-0.052773394,0.06265978700000001,1.378716015,2.53968567,-2.023537766,-1.914387321,-0.6877490390000001,-3.463144691,-1.46534671,-2.587061066,-3.939447523,1.010952053,-3.2375354766845703,-6.470340251922607,-6.536555290222168,-4.410937309265137,-5.702877521514893 -1876,1876,S122T,0.172842962,0.012916523999999999,0.0137892,0.024728273999999998,-0.048347505,-0.02444848,0.005936381,0.339749542,,0.025366199,0.000466848,0.014904175,0.012674225,0.058558463,-0.009101915,-0.029832525,-0.066862485,1.267893708,2.504631358,-2.969045012,-2.438888817,-3.637488983,-3.462279503,-3.2474143680000003,-2.059153389,-3.5087814980000003,1.0980965790000001,-3.5118260383605957,-3.03660249710083,-4.669669151306152,-2.506772041320801,-4.247453689575195 -1877,1877,S122W,0.367604559,-0.048617348,-0.030193547999999997,-0.080856729,-0.065610253,-0.028691743,0.14620867199999998,0.589000446,,0.0027017720000000003,-0.099936468,-0.025093462,-0.035293633,-0.002375619,-0.159337839,-0.099680336,-0.03154017,1.395513414,2.366341084,-7.237980917000001,-7.1118037339999995,-7.737459572000001,-6.803167792999999,-6.7763536989999995,-7.761119788999999,-5.75446124,-2.128534863,-7.186439037322998,-11.512907981872559,-10.294014930725098,-6.4390106201171875,-8.54111099243164 -1878,1878,S122V,0.426733834,-0.038884959,0.065571219,-0.011582772,-0.010096556,-0.031445699,0.137305588,0.7161620790000001,,-0.025087649,-0.052682269000000004,-0.0059369719999999996,0.137079409,-0.023463925,0.00029838200000000003,-0.049051713,0.028858601,1.136327568,2.2667833269999997,-4.515405168,-4.4106712880000005,-6.006736038,-4.609441376,-4.834155624,-2.716021515,-3.795583962,-0.28350528,-4.280963897705078,-8.294211387634277,-7.480972766876221,-3.6235544681549072,-5.219724178314209 -1879,1879,S122Y,0.036594233999999996,-0.028142597000000002,-0.026150289,-0.007976202,-0.017809198999999998,0.006122435,0.03705647,0.036131997,,-0.034832558,-0.021452635,-0.022567438,-0.029733139,0.025267531,-0.041219935,-0.034344716000000004,-0.001273681,1.340955651,2.612253322,-5.121678333999999,-4.970863602,-6.477635902,-4.128093703999999,-3.699550697,-6.332247765,-5.689018936,0.36143618299999997,-5.419336318969727,-9.609858512878418,-8.340278625488281,-3.4730708599090576,-5.862187385559082 -1880,1880,A123C,-0.280185439,-0.004247023,-0.046905697999999996,-0.034296357,-1.28428257,0.083669736,-0.156805433,-0.403565445,0.31122943399999997,-0.031892516,0.023398471,-0.0071759630000000005,-0.086635432,-0.023339686000000002,-0.045253027,-0.9779357759999999,-1.590629364,0.9652358520000001,1.404744514,-11.67593257,-10.08993374,-10.55083051,-12.70024502,-12.45265037,-12.586003199999999,-9.739678394,-6.625083582999999,-11.531838417053223,-13.329789161682129,-11.011083602905273,-10.776263236999512,-11.659207344055176 -1881,1881,A123E,-0.23981918800000002,-0.015990868000000002,-0.009362643,-1.441669809,-2.480116703,-0.025782717,-0.077738011,-0.401900365,0.179127022,-0.005856268,-0.026125467000000003,-0.036236915,0.017511629,-1.0564833409999999,-1.8268562769999999,-2.494428955,-2.465804451,0.79988404,0.755326033,-9.767012602000001,-7.23729052,-8.53442942,-11.43130537,-10.25346146,-11.37857624,-7.351486929,-3.175513342,-12.918574333190918,-15.230975151062012,-10.750835418701172,-13.094670295715332,-11.532825469970703 -1882,1882,A123D,-0.24768679600000001,0.016535884,-0.658586558,-1.514936134,-2.27741418,0.065728023,-0.038841212,-0.456532379,0.293094974,-0.014330208999999998,0.047401977000000005,-0.525803966,-0.7913691490000001,-1.439023245,-1.590849023,-2.358454919,-2.196373441,2.417369461,1.392352095,-9.140484811,-6.305842079,-8.676863861000001,-10.267077800000001,-9.581106514,-10.87153381,-7.562071424,-4.0278476880000005,-13.198934555053711,-15.313758850097656,-10.999848365783691,-12.80269718170166,-12.459720611572266 -1883,1883,A123G,-0.260528661,-0.0034585320000000003,-0.027570498,0.011865836999999999,-1.5579455690000001,0.040060509,-0.10542452,-0.415632802,0.215831415,-0.028306654,0.021389591,-0.011264472,-0.043876523,-0.008235165,0.031966839,-1.532332805,-1.583558332,0.854143894,1.3302493690000001,-6.1023016310000004,-3.943840469,-4.943286308,-8.149883513999999,-7.292417595,-6.182080269,-6.156265728999999,-3.8631742160000004,-7.8454437255859375,-10.667917251586914,-8.405450820922852,-7.938729286193848,-9.603460311889648 -1884,1884,A123F,-0.33324564100000004,0.011224287,-0.250954361,-1.39422107,-2.64344777,0.057670803,-0.22414054600000002,-0.442350736,0.247718915,-0.027337083999999998,0.049785657999999997,-0.19332558800000002,-0.308583134,-1.5624768230000001,-1.225965316,-2.628036532,-2.6588590080000003,1.1857535240000001,0.7468140240000001,-12.18665587,-11.66231805,-8.992744476,-14.28416422,-13.75072243,-12.24333016,-8.138436035,-2.99935023,-13.551671981811523,-16.49542808532715,-13.658931732177734,-13.0982666015625,-13.534869194030762 -1885,1885,A123I,-0.28281536,0.066103649,0.013376095,-0.977584401,-1.679705983,0.010823077,-0.124134829,-0.44149589100000003,0.17478902600000001,0.08894946699999999,0.04325783,0.016985613,0.009766577,-0.7741724240000001,-1.180996377,-1.7563949280000002,-1.6030170380000002,2.18436879,1.6457875419999999,-7.746696703,-7.575559509,-4.827628517,-7.810091948999999,-8.528251946000001,-9.991951591,-6.303298452999999,-4.0662751660000005,-10.941923141479492,-14.123919486999512,-12.21277141571045,-10.120895385742188,-11.407357215881348 -1886,1886,A123H,-0.222591453,0.0060726569999999995,-0.065716493,-1.46797117,-2.266565409,-0.015309103000000001,-0.081360048,-0.36382285700000006,0.24085743,-0.025540623,0.037685937,-0.071483495,-0.05994949,-1.284121285,-1.651821054,-2.24931045,-2.283820368,0.833057151,0.736014051,-11.34389446,-10.28763858,-9.163620857,-11.60489192,-10.06223399,-15.60108694,-8.242547434,-3.804352764,-15.25572395324707,-17.73906707763672,-13.298423767089844,-14.771574020385742,-14.33409595489502 -1887,1887,A123K,-0.318796332,-0.002167327,-1.222976178,-1.9995646759999999,-2.514617711,-0.063986326,-0.191014763,-0.446577901,0.187990482,-0.026377935,0.022043281,-1.008153248,-1.4377991069999998,-1.8173676980000002,-2.181761653,-2.162768104,-2.866467318,3.697827593,2.325580277,-12.30403358,-10.04480191,-9.186185318,-13.98518378,-12.29653608,-16.00746079,-7.979542192,-2.6918373439999996,-14.965312957763672,-17.743846893310547,-14.366301536560059,-15.985180854797363,-13.803897857666016 -1888,1888,A123M,-0.389051091,-0.027207689,-0.093753905,-1.553111933,-2.704317891,0.046070637000000005,-0.254399159,-0.5237030220000001,0.24057396,-0.014181656,-0.040233721,0.030792535,-0.21830034399999998,-1.3901980719999998,-1.716025794,-2.7246030930000003,-2.6840326880000003,0.676974188,0.711887917,-8.64358615,-8.824457672000001,-6.349230156,-10.44138876,-10.34778276,-7.255071396,-6.783530174,-3.085595402,-11.9203519821167,-14.461130142211914,-12.947158813476562,-11.065290451049805,-11.800915718078613 -1889,1889,A123L,-0.326070116,-0.000561003,-0.187264404,-1.320231538,-2.310294405,0.05893954,-0.18402865,-0.468111581,0.274890704,0.00421037,-0.005332375,-0.086077645,-0.288451163,-1.383759859,-1.256703216,-2.553069006,-2.067519803,0.766047135,0.7187811390000001,-9.574247033999999,-9.554737723999999,-6.507860336,-10.60663165,-11.62561115,-9.576394318,-6.657953858,-0.500251245,-12.019079208374023,-13.416861534118652,-12.209175109863281,-11.262532234191895,-12.028480529785156 -1890,1890,A123N,-0.37273222,-0.10686937199999999,-0.011476841000000002,-1.109896215,-2.7013990480000003,0.064470691,-0.212902925,-0.532561514,0.332367328,-0.133139253,-0.080599491,-0.042472061,0.01951838,-0.5662197379999999,-1.653572691,-2.082248507,-3.3205495889999996,1.7122589030000002,1.3699568640000002,-11.14018086,-8.998755005,-10.1639077,-12.48321461,-10.927424900000002,-13.1276021,-7.707709578999999,-4.479306169,-13.406094551086426,-15.565276145935059,-12.803886413574219,-13.695587158203125,-13.170188903808594 -1891,1891,A123Q,-0.382757312,-0.091981034,-0.13192312,-1.36173126,-2.533981274,0.081510005,-0.232236816,-0.533277807,0.161118336,-0.12884673900000002,-0.055115329000000005,-0.079335839,-0.18451040100000002,-1.264091652,-1.4593708680000002,-2.224916011,-2.8430465369999998,0.99923322,0.756627726,-11.37526737,-9.989266571,-8.981983077999999,-13.51394772,-10.72880686,-13.66233263,-7.3259771460000005,-2.618636681,-13.59376049041748,-16.12175750732422,-13.002717971801758,-14.271944046020508,-13.972000122070312 -1892,1892,A123P,-0.29544296600000003,-1.303264907,-1.369459938,-1.5287458090000001,-2.277657644,0.061768009000000006,-0.127254148,-0.46363178299999996,0.109867201,-1.72525497,-0.8812748429999999,-1.7626485980000002,-0.976271277,-1.9657505130000001,-1.091741104,-2.987844528,-1.56747076,-0.5273210939999999,-1.028536408,-11.02525557,-10.07382784,-10.06141911,-11.84924564,-12.17361216,-10.96817309,-8.350854372,-4.889756063,-12.661261558532715,-15.354781150817871,-12.517721176147461,-10.609687805175781,-12.4190092086792 -1893,1893,A123S,-0.25770920399999997,0.009110295,-0.014811205,0.011556071000000001,-0.275678578,0.021270194,-0.136060412,-0.37935799600000003,0.181668763,-0.016424983,0.034645573,-0.008990326,-0.020632084,-0.006522961999999999,0.029635104,-0.20039826800000002,-0.35095888799999997,1.311260259,2.041412754,-7.36018342,-6.383967772999999,-6.4935955729999995,-8.412306267,-7.5655041579999995,-7.945543327,-7.091799427000001,-3.1310374089999997,-7.507144927978516,-9.340584754943848,-7.398548126220703,-7.663389205932617,-7.796710968017578 -1894,1894,A123R,-0.26092956300000003,-0.255169872,-1.4320488230000001,-2.130741892,-2.9599893930000003,0.031329449,-0.11237097800000001,-0.409488147,0.2646768,-0.19687903899999998,-0.313460705,-1.4163487869999998,-1.447748859,-2.038823243,-2.2226605409999998,-2.711582583,-3.208396202,2.61870926,1.060856871,-10.8422903,-8.252465263,-8.575836967,-13.44795206,-9.441289474,-14.49390773,-6.374985589,-2.200517873,-14.519006729125977,-17.678516387939453,-14.295830726623535,-15.604182243347168,-14.84533405303955 -1895,1895,A123T,-0.125126247,0.00345706,0.008159428,-0.17994204,-1.5781502059999999,0.043713545,-0.09373254,-0.15651995300000002,0.15658201800000002,-0.015201832,0.022115952,0.011412206999999999,0.004906649,-0.09117516,-0.268708919,-1.691848071,-1.46445234,0.876558307,1.323936171,-7.548103804,-6.019906517000001,-6.250928284,-9.485409157000001,-7.490484306,-8.493790756000001,-7.176424602999999,-4.785366407,-8.86585807800293,-10.567855834960938,-8.642477035522461,-8.206466674804688,-8.102398872375488 -1896,1896,A123W,-0.281376845,0.023298695,-0.613395525,-1.4358704480000002,-2.6040287369999997,0.005447228,-0.14317574800000002,-0.41957794200000004,0.26011591300000003,-0.0031601859999999997,0.049757575,-0.499551266,-0.7272397829999999,-1.588374107,-1.283366788,-2.452288453,-2.7557690210000003,2.32256759,1.259818873,-13.22285313,-11.60270753,-10.2959799,-15.21126812,-14.18517313,-14.81913696,-8.100618754,-3.470832843,-15.691073417663574,-19.2371826171875,-15.399704933166504,-15.633973121643066,-15.844487190246582 -1897,1897,A123V,-0.220493947,-0.013733802,-0.046557558,-0.046080508,-1.466993592,0.08266781,-0.018667245,-0.42232064799999997,0.182850843,-0.026038743,-0.00142886,-0.03501895,-0.058096165,-0.007036873000000001,-0.08512414199999999,-1.539900443,-1.394086741,0.655303947,1.316725554,-6.858876115,-7.3159490510000005,-4.776024055,-6.953280403,-7.797590598999999,-7.451536469,-6.360495091000001,-3.574983415,-9.700250625610352,-11.207791328430176,-8.447153091430664,-8.353043556213379,-7.939980506896973 -1898,1898,A123Y,-0.280417522,-0.059911254000000004,-0.030064585,-1.6064922130000001,-2.2452688309999997,-0.001969492,-0.156881915,-0.40395312899999997,0.271199218,-0.13811466,0.018292153000000002,0.005232019,-0.065361189,-1.467849572,-1.7451348530000002,-2.563372504,-1.9271651580000002,0.7652826340000001,0.7112710859999999,-11.74887883,-10.70017768,-8.65470108,-11.64724389,-12.05583648,-15.68643504,-7.999499028,-1.627886676,-13.575281143188477,-17.686378479003906,-13.824714660644531,-13.724567413330078,-13.542191505432129 -1899,1899,A124C,-0.011634577,-0.017851698,-0.010291103000000001,0.034677989,-0.9191722929999999,0.050435432,0.013957158999999998,-0.037226313,0.029709084,0.026703897999999997,-0.062407294,0.029588992999999997,-0.050171198,0.110700666,-0.041344689,-0.615274866,-1.22306972,0.571892388,1.386581536,-10.24298311,-10.65081633,-12.1924863,-7.745605727999999,-9.61734063,-11.00866655,-7.908494062000001,-5.079621127,-8.886104583740234,-10.539688110351562,-9.749795913696289,-10.581110000610352,-11.68960952758789 -1900,1900,A124E,-0.038411508999999996,-0.8963758009999999,-2.073460304,-2.468136461,-2.721775029,0.064547819,-0.026702534,-0.050120483,0.06833848599999999,-0.682755028,-1.1099965729999999,-2.046636421,-2.1002841869999997,-2.178244903,-2.758028018,-2.430280839,-3.013269218,0.8217612679999999,-0.45077020700000003,-11.8486739,-11.70452618,-13.75140367,-9.762016578999999,-11.06749381,-12.95792925,-10.31075578,-9.737882625,-11.591962814331055,-15.172785758972168,-12.683666229248047,-14.304447174072266,-13.479796409606934 -1901,1901,A124D,-0.09018777900000001,-0.91483705,-1.7196120990000001,-2.033362845,-2.468590365,0.07118087,-0.08767097900000001,-0.09270457800000001,0.076058108,-0.81857446,-1.011099639,-1.871206692,-1.568017505,-1.905905161,-2.160820529,-2.5558811059999997,-2.3812996230000003,3.721601301,1.745826015,-12.35735396,-12.42372642,-13.95276357,-10.48531007,-11.99137843,-12.93359134,-10.31777227,-9.781867988,-12.268271446228027,-14.97785758972168,-13.407346725463867,-15.111936569213867,-14.596588134765625 -1902,1902,A124G,-0.0027064859999999997,0.057796238,0.000145854,0.027665711000000003,-1.301310383,0.05461385,0.007662751,-0.013075722,0.04140334,0.055089234,0.060503242,0.022150737,-0.021859029,0.054080289000000004,0.001251133,-1.2228733109999999,-1.379747455,0.636832294,1.332523842,-6.81752935,-7.647071999,-7.354613831,-4.697074593,-7.307185425,-7.081700905,-7.058506488,-4.496111818,-8.61917495727539,-11.152192115783691,-8.811701774597168,-8.734187126159668,-9.954883575439453 -1903,1903,A124F,-0.027110456,-1.391661003,-2.039531853,-2.371738641,-2.926407205,0.013374345,-0.028052171,-0.02616874,-0.094704317,-1.4607407380000001,-1.3225812670000001,-2.0942436630000003,-1.984820042,-1.9248221490000001,-2.818655132,-2.477888081,-3.374926328,0.347011226,-0.895631023,-16.15089619,-16.40157903,-18.29852361,-14.83403253,-14.50169779,-16.718648,-10.31777227,-9.781867969,-11.417096138000488,-15.213139533996582,-14.865737915039062,-12.928439140319824,-13.8906831741333 -1904,1904,A124I,0.020092405,0.046904718,0.0672466,-0.860383755,-1.774834631,0.090141551,0.04529354,-0.00510873,0.031281034,0.021859316,0.071950119,0.029480406,0.105012794,-0.422251014,-1.298516496,-2.32264696,-1.2270223009999999,1.4265071040000001,1.280433052,-9.165272189,-10.68651352,-11.30078786,-6.1992850189999995,-7.949799057000001,-9.689975487,-6.179921998999999,-3.511875505,-7.3657073974609375,-10.279397964477539,-11.311697006225586,-9.28917121887207,-10.7459135055542 -1905,1905,A124H,-0.03561949,-1.4380660319999998,-2.0268643,-2.1890970569999997,-3.0642546489999996,0.102773805,-0.011478255,-0.059760725,-0.080665682,-1.6150813990000001,-1.261050665,-1.78482703,-2.268901569,-1.819525499,-2.558668614,-3.071561435,-3.056947863,0.088695815,-1.0041316409999999,-13.77943121,-13.67799036,-14.79833383,-10.776526400000002,-12.50733798,-17.136967499999997,-10.31777227,-9.781868017,-15.695363998413086,-18.37237548828125,-15.570430755615234,-15.577655792236328,-16.991779327392578 -1906,1906,A124K,0.012278438000000001,-1.552713314,-2.0301051930000003,-2.458254744,-3.012923308,0.060417198,0.049038529000000004,-0.024481653,-0.08171551,-1.4604015780000001,-1.64502505,-2.035912556,-2.024297829,-2.1675210380000003,-2.74898845,-2.7205869689999997,-3.305259646,0.276536292,-0.9192750009999999,-13.23416453,-12.93221961,-14.73641473,-10.16145316,-12.1447118,-16.19602334,-10.31777227,-9.781867995,-16.13181495666504,-18.34375762939453,-16.997127532958984,-16.6966552734375,-16.078845977783203 -1907,1907,A124M,-0.063068996,-0.003268258,-0.014727211,0.027366344,-1.8479598659999998,0.019126091,-0.047494325,-0.078643666,0.058836012,0.058684178,-0.065220693,0.055677948,-0.08513237,0.086701178,-0.03196849,-1.60519355,-2.090726181,0.414995159,1.304244792,-8.963420807,-10.36260567,-11.86793983,-5.932270409,-7.6753243939999996,-8.97896373,-6.300651534,0.16170137099999998,-8.216789245605469,-10.562366485595703,-10.79299545288086,-9.225531578063965,-10.330079078674316 -1908,1908,A124L,0.003243602,0.014383091,-0.16920965300000002,-1.53856309,-2.491934679,0.011818531,0.01393761,-0.007450406999999999,0.017757,-0.024067934,0.052834115,-0.174618395,-0.16380091,-1.259976709,-1.81714947,-2.3271474619999997,-2.656721895,1.184126442,0.7973790340000001,-12.75066125,-13.00720635,-15.15957541,-9.397731627999999,-11.29902584,-14.88976703,-7.693431397,-4.880356316,-9.84069538116455,-12.574352264404297,-12.429548263549805,-10.079011917114258,-11.708590507507324 -1909,1909,A124N,-0.039626014,-0.008471771999999999,-0.028157772999999997,-1.207287424,-2.7414766839999998,0.015503517,-0.036035639,-0.043216388,-0.041601659,-0.029751527000000003,0.012807984,-0.07147410000000001,0.015158554,-0.8347344459999999,-1.5798404019999999,-2.2007137340000003,-3.282239633,1.790684639,1.339065403,-10.6062467,-10.34700438,-12.3388198,-7.862363212999999,-10.39596574,-12.08708037,-8.010214371,-4.99488381,-12.037129402160645,-13.742729187011719,-12.361597061157227,-12.63500690460205,-13.345669746398926 -1910,1910,A124Q,-0.05570425,0.044020779,-0.877571678,-1.851658241,-2.8327192389999998,0.086177941,-0.06602153,-0.04538697,-0.03298095,0.019766112,0.06827544599999999,-0.5651314789999999,-1.190011876,-1.6719163769999998,-2.0314001040000003,-2.577164827,-3.08827365,1.878655473,0.9166395270000001,-12.82643978,-12.754561,-13.977384900000002,-10.14203616,-11.78095783,-15.477259,-10.12751286,-8.788685144,-12.77208137512207,-16.50929832458496,-13.614693641662598,-13.84945011138916,-15.251326560974121 -1911,1911,A124P,-0.040167367,-1.507453586,-1.8890531330000002,-2.102559946,-2.842762441,0.040570557,-0.033665618,-0.046669116,-0.043785475,-1.580527939,-1.434379232,-1.7996440040000001,-1.978462261,-1.8273563519999998,-2.37776354,-2.353550137,-3.3319747439999996,-0.037768281,-1.003528998,-11.74818231,-12.28343485,-12.97845091,-9.607790572999999,-11.17090613,-12.70032908,-10.31777227,-9.781868054,-13.390443801879883,-14.994369506835938,-13.772284507751465,-11.148208618164062,-13.333847045898438 -1912,1912,A124S,0.003944871,0.032996437,-0.01380044,-0.014520593,-0.166790065,0.022708655,-0.0007364089999999999,0.008626151,0.014726153999999998,0.043625708,0.022367165,-0.030297945,0.002697065,0.009615455,-0.03865664,-0.127621375,-0.205958755,1.540928459,2.447448777,-4.570665341000001,-4.335074066000001,-5.41764975,-3.269036613,-5.129985802,-4.701580475,-4.955573663,-1.558094527,-6.293313503265381,-6.779776573181152,-6.633975505828857,-6.67789888381958,-7.340600490570068 -1913,1913,A124R,-0.021502245,-1.450598755,-1.849036898,-2.212339794,-2.826507129,0.048507135,-0.005208739,-0.03779575,0.0023197879999999997,-1.551848695,-1.349348814,-1.744142921,-1.953930875,-1.8196354609999998,-2.6050441269999998,-2.812034086,-2.840980172,0.057161815,-0.9403973440000001,-12.76864804,-12.83098136,-13.31063694,-10.02874359,-11.69906257,-15.97381574,-9.484012134,-6.9606561870000005,-16.8133544921875,-19.159343719482422,-17.62497329711914,-16.897611618041992,-17.111392974853516 -1914,1914,A124T,0.000719217,0.02123136,-0.007647773,0.021103466,-0.065903937,0.029218228,-0.006012639,0.007451073000000001,0.13944099699999998,0.066929433,-0.024466712999999998,0.009987303000000001,-0.025282849,0.042784322,-0.00057739,-0.032283877,-0.09952399599999999,1.270488892,2.533330658,-2.1556347369999997,-2.22340197,-4.0198521419999995,-0.36787730399999996,-1.877604225,-2.289438042,-3.405556116,-0.809660258,-4.899971961975098,-4.020181655883789,-4.872550010681152,-4.970085144042969,-5.708547592163086 -1915,1915,A124W,-0.015929685,-1.538998013,-1.7218423840000001,-1.871475424,-3.152292824,0.042997717000000005,-0.00702903,-0.024830339,-0.074706783,-1.604930001,-1.473066024,-1.56579186,-1.8778929080000002,-1.697400341,-2.0455505069999997,-2.773345018,-3.5312406289999996,3.990469557,1.77616925,-15.122767000000001,-15.23706037,-17.13106564,-12.85037509,-13.47403239,-16.92130152,-10.31777227,-9.781868041000001,-14.928960800170898,-18.900047302246094,-16.69487762451172,-15.943668365478516,-17.688390731811523 -1916,1916,A124V,-0.018007089,0.052014685,0.016972908000000002,0.030278532,-1.107471463,0.019667096999999998,0.0077378740000000005,-0.043752052,0.023896711,0.07866748900000001,0.025361881,0.029620782999999998,0.004325033,0.080564472,-0.020007408,-0.84262122,-1.372321706,0.10941661300000001,1.317462885,-7.77839187,-9.537791602999999,-9.901490677,-5.698830536,-7.175420654,-6.57842588,-6.679351416,-3.792301065,-6.521588325500488,-8.232036590576172,-8.820305824279785,-7.343178749084473,-8.807345390319824 -1917,1917,A124Y,0.107512755,-1.657628385,-2.063686512,-1.918772045,-2.822925611,0.039033983,0.13006011,0.0849654,-0.02596662,-1.5050719730000002,-1.810184796,-2.013636161,-2.1137368619999997,-1.8442146469999998,-1.9933294419999998,-2.6983105739999997,-2.947540647,3.6661911810000003,1.30648619,-16.2577343,-15.79048249,-17.97996777,-14.38175153,-14.37147392,-18.76499578,-10.31777227,-9.781868022000001,-13.143146514892578,-17.121540069580078,-16.40625,-14.617776870727539,-16.919578552246094 -1918,1918,I125A,-0.066218315,-0.02517663,-0.03068767,-1.371419929,-2.202247019,-0.006927925,0.065395883,-0.197832512,-0.186011717,-0.09774527699999999,0.047392018,-0.07909796,0.01772262,-1.062871417,-1.67996844,-2.392808387,-2.01168565,1.151955893,0.8277126440000001,-9.632787195,-10.4586629,-11.85987718,-7.99991008,-7.784791779,-10.06069404,-7.133038135,-4.038124583,-7.4326677322387695,-8.722293853759766,-7.860255241394043,-9.16043758392334,-10.850558280944824 -1919,1919,I125C,-0.085918485,0.023420327,-0.02902827,-0.040319375,-0.9684338779999999,-0.049620542999999996,0.014301577,-0.186138547,-0.17057713,-0.017195359,0.064036013,-0.020493871,-0.037562669,-0.029334441,-0.051304309000000006,-0.93943662,-0.997431135,0.7237552840000001,1.3664607990000002,-12.67294516,-13.83719751,-14.60306833,-11.87865926,-11.53440368,-11.51139702,-8.706265344,-6.381182717000001,-10.162079811096191,-12.126701354980469,-10.979050636291504,-11.167045593261719,-13.568164825439453 -1920,1920,I125E,-0.087453285,-0.759172385,-2.04802089,-2.212835244,-2.8223329510000004,0.029572399,0.07154856,-0.246455129,-0.140257257,-0.68500464,-0.83334013,-2.230979969,-1.86506181,-1.953431069,-2.472239418,-2.862198189,-2.782467712,1.17711777,-0.34382865700000004,-13.15275744,-13.3660434,-13.57445417,-12.06144122,-12.95555928,-13.80628915,-8.472607369,-5.290135811,-7.898635387420654,-14.419353485107422,-10.8448486328125,-11.72785472869873,-13.072872161865234 -1921,1921,I125D,-0.043250388,-1.23294631,-1.846684855,-2.297547593,-2.81996692,-0.009370877,0.084816478,-0.17131725399999997,-0.089828108,-1.114677691,-1.351214928,-2.017200344,-1.6761693659999999,-2.089899462,-2.505195723,-2.426569814,-3.2133640260000003,3.498822347,1.2872072959999998,-15.45085988,-15.85219949,-16.96023816,-14.21911049,-15.23976995,-14.982981299999999,-10.44602202,-9.899372265,-8.411060333251953,-15.980302810668945,-11.616211891174316,-15.257944107055664,-14.948062896728516 -1922,1922,I125G,-0.085113422,-0.623324248,-1.7214663680000002,-2.114614389,-2.841845031,0.006625474,0.052978254,-0.22320509800000002,-0.12112134699999999,-0.596861318,-0.649787177,-1.770678779,-1.672253956,-1.991041448,-2.238187329,-2.836465903,-2.8472241589999996,3.1418186269999997,1.252099801,-13.67901249,-12.22365531,-15.41863157,-13.0977311,-13.47898462,-14.17605985,-8.260474514,-4.271797873,-9.817676544189453,-13.517705917358398,-11.935364723205566,-13.240039825439453,-13.12689208984375 -1923,1923,I125F,-0.089519974,-0.046757140999999995,-1.39250929,-2.344657527,-2.7595721930000003,0.0028256809999999996,0.045280693,-0.22432064,-0.129425461,-0.126160335,0.032646054,-1.2312586140000001,-1.5537599659999999,-2.261205752,-2.4281093019999997,-2.801996087,-2.717148298,1.253027147,0.17986480600000002,-13.29175462,-14.14558376,-12.92468789,-13.18209433,-13.44737045,-12.75903665,-10.21122244,-8.727994678,-9.307697296142578,-11.900644302368164,-11.532012939453125,-9.226805686950684,-9.95350456237793 -1924,1924,I125H,-0.064018194,-0.033090676,-0.17304318100000002,-1.724238004,-2.754127506,0.030696402,0.108618837,-0.236655225,-0.298766759,-0.07846025400000001,0.012278903,-0.149246531,-0.19683983,-1.4847577269999999,-1.96371828,-2.183155915,-3.325099097,1.124195569,0.742497521,-15.34487425,-15.44721692,-15.85189713,-14.75411645,-14.92171118,-15.74942957,-10.44602202,-9.899372265,-9.721131324768066,-17.22421646118164,-13.134944915771484,-13.409614562988281,-14.008467674255371 -1925,1925,I125K,-0.10895137099999999,-1.5485330990000001,-2.170276038,-2.170831092,-3.2663144369999997,0.041149222,0.022168692,-0.240071433,-0.16199365300000002,-1.470494494,-1.626571704,-2.163757524,-2.176794551,-2.090328607,-2.251333576,-2.87415699,-3.6584718830000003,0.448169435,-0.92653349,-14.17258681,-14.86128167,-14.02128481,-12.82601785,-13.89949456,-15.25485519,-10.44602202,-9.899372265,-11.508159637451172,-15.405401229858398,-14.367972373962402,-12.629108428955078,-13.383746147155762 -1926,1926,I125M,-0.08740421699999999,-0.0021787679999999998,-0.020846168999999998,-0.073686246,-0.156435923,-0.050391452,0.015575136000000002,-0.19038357,-0.09043597699999999,-0.052232374000000005,0.047874839,-0.057767402999999995,0.016075066000000002,-0.053883256,-0.09348923599999999,-0.166106878,-0.146764968,1.479126336,2.235439682,-4.692622585,-5.405469398999999,-4.86990049,-2.79810006,-4.525911736,-5.863731239,-5.04142236,-1.3043486359999998,-5.180609703063965,-7.695888519287109,-6.767887115478516,-5.41759729385376,-6.077676773071289 -1927,1927,I125L,-0.059889110999999995,0.001477955,-0.00032826,-0.010313168000000001,-0.138641855,0.005385777,0.062754299,-0.18253252,-0.177111928,-0.05877724,0.061733149,-0.028143223,0.027486702999999998,-0.011568446000000001,-0.00905789,-0.14662007400000002,-0.130663636,1.458762804,2.272174879,-4.374294254,-5.128769363,-4.159971283,-4.483471321000001,-4.140386772,-3.958872528,-4.172423375,-0.812654203,-4.531518936157227,-7.288395881652832,-6.7855682373046875,-3.463407516479492,-6.839535713195801 -1928,1928,I125N,-0.05297929,-0.026202272000000002,-0.065629432,-1.740376481,-3.007071167,-0.019573786,0.085101654,-0.191060233,-0.23904744,-0.12019612,0.06779157599999999,-0.068528717,-0.062730147,-1.40715287,-2.073600092,-2.864397153,-3.14974518,1.294871011,0.797201422,-12.69898209,-13.0122295,-15.21546893,-11.76786314,-12.267631100000001,-11.23171778,-7.93265264,-5.7566761170000005,-7.121068477630615,-13.1771240234375,-10.659543991088867,-11.998311996459961,-12.80984878540039 -1929,1929,I125Q,-0.113961714,-0.037409147999999996,-0.998846248,-2.025853157,-3.349302481,0.039589344,0.013010218,-0.240933645,-0.164622079,-0.12220702,0.04738872400000001,-0.8536468070000001,-1.144045688,-1.6984230280000001,-2.353283286,-3.1142746260000003,-3.584330335,2.308399774,1.070785477,-11.77680745,-11.623182400000001,-11.03226245,-10.88130802,-11.8924221,-13.45486229,-7.345021974,-3.634575228,-6.816019535064697,-13.897394180297852,-10.447125434875488,-8.212051391601562,-11.226563453674316 -1930,1930,I125P,-0.077798854,-1.4766592159999998,-1.927895247,-2.247869636,-3.0059348189999997,0.00434125,0.056781372000000004,-0.212379079,-0.208805606,-1.6326629259999998,-1.320655505,-1.973743438,-1.882047055,-2.252497039,-2.243242233,-2.668348637,-3.343521001,0.151369032,-1.067627717,-14.54948802,-15.40013929,-16.18685442,-13.32877854,-13.75698258,-14.07468529,-10.44602202,-9.899372265,-12.554363250732422,-16.525981903076172,-16.84307861328125,-12.07846450805664,-14.477080345153809 -1931,1931,I125S,-0.048179437,-0.007946613,-0.209213757,-1.773380575,-2.5377802419999997,0.016205812,0.096695553,-0.193054427,-0.16234369699999998,-0.09518305199999999,0.079289826,-0.183281055,-0.235146458,-1.428665184,-2.118095966,-2.629507457,-2.446053027,1.291391193,0.791153126,-11.52292218,-12.04883678,-15.11985659,-10.38802359,-10.16480795,-9.893085968,-7.228587276,-5.227952483999999,-8.308934211730957,-10.712688446044922,-9.813236236572266,-11.24482250213623,-12.21744155883789 -1932,1932,I125R,-0.092362957,-1.493834196,-2.0401370919999997,-2.4096361809999998,-3.247099866,0.049311093,0.061986396,-0.246712309,-0.194976603,-1.5057219130000001,-1.481946478,-1.948647656,-2.131626527,-2.215166801,-2.604105561,-2.880895872,-3.61330386,-0.038773228,-1.1700025059999999,-14.90523118,-15.27754626,-15.35742747,-13.56438597,-14.0873095,-16.2394867,-10.44602202,-9.899372265,-11.834383010864258,-16.577125549316406,-14.316423416137695,-13.024100303649902,-14.243935585021973 -1933,1933,I125T,-0.022518601,0.047943911,-0.0027592890000000003,-0.006095356999999999,-1.533516229,0.011945543000000001,0.11271869699999999,-0.157755898,-0.057020278,-0.001361569,0.09724939099999999,-0.017622213,0.012103635,-0.018069937,0.005879223,-1.595489167,-1.47154329,0.6925575340000001,1.315981425,-7.983609261000001,-9.702725815,-10.37699564,-6.019796539,-6.819969376,-6.998558929,-6.17068232,-2.9386510269999997,-6.908843994140625,-7.770659923553467,-7.026751518249512,-8.08561897277832,-9.334592819213867 -1934,1934,I125W,-0.08926104900000001,-1.627393401,-2.172661274,-2.345992298,-3.393020637,-0.026331027000000003,0.055831030999999996,-0.234353129,-0.20516557600000002,-1.813988185,-1.4407986169999998,-2.008940661,-2.336381887,-2.287694262,-2.404290333,-2.895431387,-3.890609886,0.040009433999999997,-1.139187731,-14.648040599999998,-15.63006039,-14.81217919,-13.83116146,-14.26786879,-14.69893316,-10.44602202,-9.899372265,-10.95053768157959,-17.778564453125,-15.606188774108887,-14.73341178894043,-14.348871231079102 -1935,1935,I125V,-0.038372132999999996,0.009569356999999999,-0.019422379,-0.039457358,-0.082027902,-0.048501435999999995,0.08943123900000001,-0.166175504,-0.105345494,-0.073285006,0.092423719,-0.054879248,0.016034491,-0.0485214,-0.030393315,-0.098407374,-0.06564843,1.3688381230000002,2.3379272209999997,-2.047635144,-2.0356755069999997,-2.351994377,-2.005875168,-1.8398718719999998,-2.004758797,-4.110159854,-0.643668394,-3.7842788696289062,-4.463613033294678,-4.070446968078613,-4.133580207824707,-6.194433689117432 -1936,1936,I125Y,-0.068701061,-1.252592752,-1.808803546,-2.245651922,-3.116589002,0.035697627999999995,0.09657989300000001,-0.233982014,-0.088170845,-1.403368945,-1.101816558,-1.853593927,-1.764013165,-2.266241107,-2.225062736,-2.6309401830000003,-3.60223782,3.386721034,1.070588895,-14.89165804,-15.6022628,-15.16128007,-14.22550773,-14.67087075,-14.79836886,-10.44602202,-9.899372265,-10.28007698059082,-14.997770309448242,-14.097757339477539,-12.355575561523438,-14.025456428527832 -1937,1937,T126A,-0.17667349699999998,0.02516144,0.011372337,0.007038443,-0.120109387,-0.028940865,-0.034777551000000004,-0.318569442,0.005589881999999999,0.003542361,0.046780518,-0.018008764,0.040753437999999996,-0.018139434,0.03221632,-0.12316190699999999,-0.117056866,1.3750317619999999,2.206857663,-5.7931175139999995,-4.99081427,-5.499103187999999,-6.02096032,-5.733378197,-6.721331596000001,-4.146223913,-1.4428003169999999,-7.893303871154785,-9.505903244018555,-7.38956356048584,-7.676030158996582,-7.310238838195801 -1938,1938,T126C,-0.170671271,0.053424704,0.021207442000000003,0.034808558999999996,-0.18049420800000002,0.051298663,-0.014465132,-0.32687741,-0.066769418,-0.022129307,0.128978714,-0.025209718,0.06762460099999999,-0.044825860999999995,0.114442978,-0.273467589,-0.087520826,1.201224261,1.8385216919999998,-11.10441903,-9.374317329,-11.53553254,-12.0258579,-12.34781847,-10.23856892,-6.724662151,-3.430291763,-11.027444839477539,-11.384432792663574,-9.769129753112793,-11.092836380004883,-10.760940551757812 -1939,1939,T126E,-0.226593963,0.011359515,-0.011120608,-0.021424414,-0.021148682999999998,-0.04611073,-0.069677933,-0.383509993,-0.106197796,0.036863446,-0.014144417,0.003948511,-0.026189726,-0.021818247000000002,-0.02103058,-0.0016149329999999998,-0.040682433,1.242359974,2.550598346,-7.4360719379999995,-6.285330719,-5.827951118,-6.75056414,-10.29507455,-8.021439163,-4.458323879,-2.018964078,-6.890834331512451,-11.156601905822754,-6.482416152954102,-7.157785892486572,-7.383288383483887 -1940,1940,T126D,-0.135070456,0.030407816,0.016024766,0.033439849,-1.327968144,0.021901772000000003,0.034626233,-0.304767145,0.08915615800000001,-0.025161897000000003,0.085977529,-0.069127378,0.10117691,-0.017465956,0.084345654,-1.079401729,-1.576534558,0.662473875,1.344273693,-8.294395633999999,-6.775618446,-9.668968216,-7.239932098,-11.0876373,-6.699822113,-4.614884053,-2.883381151,-9.60715103149414,-12.624131202697754,-7.2433366775512695,-10.294549942016602,-9.966561317443848 -1941,1941,T126G,-0.20265891800000002,0.025132771,-0.008218524,-0.03074706,-0.090434344,-0.034886636,-0.033319193999999996,-0.371998641,-0.06471837700000001,-0.030806115,0.08107165599999999,-0.055496355,0.039059308,-0.07495613,0.013462011000000001,-0.133608651,-0.047260036,1.359925915,2.1595304680000003,-9.182486665,-7.142824554,-7.994976532000001,-10.234038499999999,-10.91756342,-9.623030327,-5.753374696,-2.944078448,-9.391486167907715,-11.986471176147461,-9.175443649291992,-10.627561569213867,-9.009418487548828 -1942,1942,T126F,0.006165254,-0.0047010820000000005,-0.168111795,-2.150199067,-2.7577696539999996,0.07459228400000001,0.038144394,-0.025813886,-0.18987954399999998,-0.036298263,0.026896099,-0.22621001,-0.11001358,-1.773063661,-2.5273344719999997,-2.7021807489999996,-2.8133585589999996,1.259639343,0.727886002,-14.08599279,-11.66260291,-13.55068627,-16.27610898,-17.7742057,-11.16636011,-8.276247201,-6.7211680629999995,-11.124619483947754,-14.554935455322266,-12.115205764770508,-11.330613136291504,-11.584358215332031 -1943,1943,T126I,0.054975047,0.030746957999999998,-0.041504527,-0.05454051099999999,-0.6284574239999999,-0.080044696,-0.040493251,0.150443344,0.08887405699999999,-0.011003441999999999,0.072497358,-0.020602716,-0.062406338,-0.040973498,-0.068107524,-0.49116353,-0.765751317,0.940488928,1.525378031,-7.728511931,-6.148190926,-9.093715935,-9.060529358,-10.13842004,-4.2017034,-4.497360546,-0.8895317090000001,-7.8628058433532715,-10.563599586486816,-8.396713256835938,-7.154366493225098,-7.939888954162598 -1944,1944,T126H,-0.239146334,0.063781465,-0.004860651,-0.001251264,-1.590108896,-0.058663825,-0.055126302,-0.423166366,-0.033648449,0.025202891,0.102360039,-0.001900662,-0.00782064,0.025630136,-0.028132663,-1.5977363180000002,-1.582481473,0.569519494,1.3087406240000001,-12.44205402,-11.35238619,-9.833808563,-11.49268142,-14.26170677,-15.26968714,-6.877052542,-4.659106153,-8.794358253479004,-12.79239559173584,-9.43779182434082,-11.028108596801758,-11.083949089050293 -1945,1945,T126K,0.01733511,0.023398911,0.011957141000000001,-0.030240171,-1.358378399,-0.064843736,0.016390416,0.018279804,-0.292541885,-0.0272154,0.074013222,-0.01196888,0.035883161000000004,-0.03820093,-0.022279411000000002,-1.240962213,-1.475794585,0.9093670620000001,1.360252077,-11.04969965,-9.591318314,-8.981144516,-10.27202608,-12.63486887,-13.76914048,-6.343623046,-3.0137204410000002,-8.461480140686035,-10.693987846374512,-10.46651554107666,-9.384353637695312,-9.262601852416992 -1946,1946,T126M,-0.115175431,-0.007546683,-0.061007772,-0.09849358400000001,-0.243990837,-0.043653135,-0.12583976300000002,-0.10451109800000001,-0.252931289,-0.002569797,-0.012523568,-0.036320395,-0.085695149,-0.048807859,-0.148179308,-0.23358025899999998,-0.254401415,1.421229036,2.038108655,-10.56531313,-9.569071037,-10.97642991,-11.91582149,-12.64020019,-7.725043007000001,-6.354604851,-3.815295743,-8.484549522399902,-10.749643325805664,-8.101394653320312,-7.013424873352051,-6.22250509262085 -1947,1947,T126L,-0.096693993,0.035541718,-0.010968823999999999,0.0010304160000000001,-0.8616577240000001,-0.046596676,0.023362429,-0.216750415,0.0015989589999999998,-0.018677819,0.089761254,-0.050693495,0.028755847,-0.018561561,0.020622392,-0.705767945,-1.017547503,0.868131709,1.4329410059999999,-10.14548396,-9.405060966,-10.993181100000001,-9.426929031,-12.99801671,-7.9042319789999995,-4.988605195,-3.096857965,-8.833155632019043,-11.399202346801758,-8.437206268310547,-8.650918960571289,-8.302099227905273 -1948,1948,T126N,-0.009998497,0.047442564000000007,0.009316461,0.018008128999999998,-1.293054109,-0.055926693,-0.022355494,0.0023585,-0.083826151,-0.007764649,0.102649776,-0.054309467,0.07294238900000001,0.006685216,0.029331042,-1.3666945959999999,-1.219413622,0.65737133,1.323494795,-9.602508217,-8.343792046,-7.808517845,-9.491787117000001,-12.49008698,-9.878357101,-6.957415086,-4.135898254,-8.2987060546875,-10.90688419342041,-8.31614875793457,-9.091296195983887,-8.875755310058594 -1949,1949,T126Q,-0.278037364,0.0033200179999999997,-0.032037934,0.0010746339999999999,-0.287981456,0.002231299,-0.09146629099999999,-0.464608436,-0.197389145,-0.051920839,0.058560875,-0.018034438,-0.046041429,-0.013355500000000001,0.015504768,-0.241967972,-0.333994939,1.582549604,2.193047553,-9.394827292,-8.883511459,-7.265637672,-8.392173202999999,-10.37076799,-12.06204613,-5.2495347169999995,-1.257722168,-4.734274864196777,-9.274054527282715,-7.57249641418457,-7.12932014465332,-8.024137496948242 -1950,1950,T126P,-0.05767008,0.01881771,-0.764687577,-1.751438869,-2.750667125,0.013981713,-0.040171266000000004,-0.075168893,-0.12452649699999999,-0.017884181000000002,0.055519600999999995,-0.54003178,-0.989343374,-1.6141709819999999,-1.888706756,-2.651114497,-2.8502197519999997,1.9487310409999998,0.9752429859999999,-12.96601012,-12.04315368,-12.60910185,-13.01417787,-13.805678899999998,-13.35793828,-9.77976323,-9.131236502,-11.806866645812988,-14.804725646972656,-13.228767395019531,-12.604419708251953,-11.688470840454102 -1951,1951,T126S,0.11817350199999999,0.05207628,-0.03551794,-0.02157785,-0.028377463999999998,-0.011246935,0.018914723999999997,0.21743227899999998,0.006415102,-0.027350463,0.131503022,-0.078035257,0.0069993780000000005,-0.052973375,0.009817675,-0.099893766,0.043138839000000005,1.4890498559999998,2.394101586,-4.383847255,-3.326948158,-3.611209122,-5.1422601089999995,-5.062231842,-4.776587043999999,-4.611230074,-0.964335235,-6.429322719573975,-7.894166946411133,-5.904171943664551,-6.904930114746094,-6.058513164520264 -1952,1952,T126R,-0.194517857,0.020742066,-0.001751331,0.018190034,-1.4194100180000002,-0.07921840200000001,-0.041646191,-0.347389523,-0.069441308,-0.02500302,0.06648715200000001,-0.018821307,0.015318645,-0.008552750999999999,0.044932819000000006,-1.40808033,-1.430739705,0.49979370100000003,1.315191444,-9.796206619,-10.33786086,-5.930782623,-9.140552422,-9.848872414,-13.72296478,-4.130640631,-0.929608928,-6.380775451660156,-11.533164024353027,-9.57970905303955,-9.278301239013672,-8.239828109741211 -1953,1953,T126W,-0.22908248899999997,0.027459781000000003,0.0012450039999999999,-1.305275812,-1.963531436,0.048581084000000004,-0.042909647999999995,-0.41525533,-0.123244635,0.022612826000000003,0.032306736,-0.015261058999999999,0.017751066,-1.0241626609999999,-1.586388963,-2.259704776,-1.667358095,0.825755586,0.761792895,-15.30228653,-13.22078146,-15.85339976,-16.18777871,-16.1401834,-15.1092893,-7.4525266960000005,-5.571198613,-11.622407913208008,-14.665050506591797,-11.593666076660156,-13.704333305358887,-13.850915908813477 -1954,1954,T126V,-0.19846640899999998,0.0203496,-0.014448073999999998,-0.037117988,-0.38237527299999996,-0.029002661000000002,-0.036838407999999996,-0.36009441,-0.0020152910000000002,-0.02119364,0.061892839000000005,-0.030851514,0.001955366,-0.061134528,-0.013101448,-0.296762893,-0.46798765299999995,1.318634597,1.90821595,-7.150633237,-5.983161682,-7.573802505,-8.561071411,-8.021590377999999,-5.613540207000001,-4.7815190030000005,-1.305373847,-7.362701416015625,-10.04537582397461,-7.117293834686279,-6.685053825378418,-7.917250156402588 -1955,1955,T126Y,-0.29396024,0.04063387,-0.037705083,-1.398911126,-2.701306344,0.010168301999999999,-0.11574194199999999,-0.472178537,-0.114977095,0.001442949,0.07982479,-0.052002895,-0.023407271,-0.9016019259999999,-1.896220326,-2.983007358,-2.419605329,0.807378155,0.7760887190000001,-13.65478704,-10.7361521,-12.05254279,-15.80411532,-16.49321675,-13.18790826,-7.2701155879999995,-5.048094289,-10.376296997070312,-13.577936172485352,-10.930198669433594,-11.069781303405762,-12.732320785522461 -1956,1956,M127A,0.7372199970000001,0.029317033,-0.071418003,-0.06272261900000001,-0.6926908359999999,-0.063705055,-0.021008381,1.495448375,,-0.003451865,0.062085931,-0.014806191000000002,-0.128029814,-0.003512012,-0.12193322599999999,-0.39651343299999997,-0.988868238,1.035528788,1.6292598980000002,-7.082077161,-6.7450818329999995,-7.523826004,-7.563333618,-7.471268532000001,-6.1068758160000005,-6.542859728,-1.391320006,-5.512395858764648,-9.14958381652832,-6.7249860763549805,-8.455883026123047,-9.864034652709961 -1957,1957,M127C,0.11857437800000001,-0.018297834,-0.040678448,-0.017391625,-0.48694673299999996,-0.009454121,-0.058265174,0.29541393,,-0.017858406,-0.018737262,-0.046946969000000005,-0.034409926,-0.030666684,-0.0041165659999999995,-0.33115668,-0.6427367860000001,1.2766628,1.8334368509999999,-10.58717039,-9.447184036,-10.43770061,-10.76744659,-10.96046327,-11.32305745,-8.76576791,-4.460167805,-6.821384906768799,-10.002496719360352,-6.270402431488037,-8.858979225158691,-10.666573524475098 -1958,1958,M127E,0.096189551,-0.016611354,-0.014242088,-0.024533059,-0.163903742,-0.032680028,-0.06691256799999999,0.259291669,,0.046085136,-0.079307844,0.01576864,-0.04425281599999999,-0.007480884,-0.041585234,-0.051374002,-0.27643348100000004,1.16497741,2.371227882,-7.552246407999999,-6.871036591,-7.586551071000001,-8.248684227,-8.113047348,-6.941912803999999,-5.6279224910000005,0.517089235,-5.3806538581848145,-11.000871658325195,-5.791038990020752,-7.823883533477783,-9.22221851348877 -1959,1959,M127D,1.093056988,-0.09596679699999999,0.166986457,0.200758563,-0.936038974,-0.036453617,0.213074825,1.97303915,,0.060374433,-0.252308026,0.036033994,0.29793891899999997,0.0035771170000000003,0.397940009,-0.7862996959999999,-1.085778251,0.725158678,1.386158154,-10.60666189,-9.163905205,-13.4295986,-10.29794485,-9.984998222,-10.15686257,-6.516256971000001,-0.403004927,-6.828519821166992,-12.56386947631836,-6.570308685302734,-9.819914817810059,-11.84390926361084 -1960,1960,M127G,0.315820581,0.021604144,-0.01518756,0.024761447000000002,-1.497130957,-0.039307939,0.017019044,0.614622118,,0.052876664000000004,-0.009668376,0.00601708,-0.036392199,0.040351931,0.009170963,-1.4763386930000002,-1.517923221,0.644506104,1.31673331,-10.35471973,-9.279828117000001,-9.760237656000001,-10.46521534,-11.24045035,-11.02786718,-7.60840406,-3.098645173,-7.022405624389648,-11.584573745727539,-9.443334579467773,-11.328030586242676,-12.786333084106445 -1961,1961,M127F,-0.036729682,0.009536845,-0.004058365,0.00638292,-0.309422693,-0.006582265,-0.048754267999999996,-0.024705096,,0.027334384,-0.008260694,0.062983416,-0.071100145,0.056641227,-0.043875388,-0.149390382,-0.469455004,1.3655875430000002,2.22789784,-7.1902039570000005,-5.756568871,-6.985108962999999,-7.212079796,-8.330140434,-7.667121719,-4.9124201869999995,-0.339359106,-3.745621919631958,-7.739596366882324,-2.803211212158203,-5.145086288452148,-6.179533004760742 -1962,1962,M127I,0.08159153799999999,0.010909596,-0.0028349620000000003,-0.0038032990000000004,-0.12632389800000002,0.00738454,-0.022330435,0.18551351,,-0.017562752,0.039381942999999996,-0.011722225,0.006052302,0.013294038000000001,-0.020900635,-0.110721739,-0.141926057,1.3862942759999999,2.307707135,-3.5799967560000003,-3.063875626,-3.282390732,-3.177001747,-5.009045853,-3.367669823,-4.299826274,0.768950719,-4.897838115692139,-6.930020809173584,-3.618109703063965,-4.641371726989746,-7.460311412811279 -1963,1963,M127H,-0.1267838,-0.002129527,-0.014032138999999999,-0.00283735,-0.7132525,0.003345148,-0.012621743999999999,-0.240945855,,0.018526128,-0.022785182,-0.028887146000000002,0.0008228689999999999,-0.028932892999999998,0.023258192999999996,-0.563783551,-0.862721449,0.965565392,1.5113700069999998,-8.453265498,-5.756870308,-9.507846596,-8.982190681,-10.25468877,-7.76473114,-6.202551862000001,0.11060269,-3.8527581691741943,-8.878182411193848,-4.465577125549316,-6.128268718719482,-8.000487327575684 -1964,1964,M127K,-0.030666195,0.0038294559999999997,0.04983254,0.022735163,-0.578754318,-0.07565506799999999,-0.015807187,-0.045525202,,-0.004224813,0.011883725,0.04525503,0.054410049,0.039408291,0.006062035,-0.311014784,-0.846493851,0.9585498920000001,1.656834925,-6.8882866410000005,-6.14394117,-6.855686172,-7.764972649,-8.718545752999999,-4.95828746,-5.725738405,-0.401553496,-4.8607001304626465,-8.944846153259277,-7.456908226013184,-6.931981086730957,-7.133006572723389 -1965,1965,M127L,-0.219845667,0.011461458,0.01146416,0.040917756,0.005314044,-0.023096678,-0.031636807,-0.40805452600000003,,-0.003082868,0.026005782999999998,0.022139267,0.0007890530000000001,0.011718675,0.070116836,0.014403937,-0.00377585,1.197901555,2.649089193,-1.70865825,-0.873971176,-2.149725998,-1.4605851669999999,-2.358745293,-1.7002636180000001,-3.55071335,1.061192272,-3.2692012786865234,-4.686761379241943,-2.718973159790039,-3.2395172119140625,-4.427953720092773 -1966,1966,M127N,0.191001723,0.046361299,0.031755263,0.047141745,-0.767545404,-0.01430906,-0.07114167099999999,0.453145116,,0.09071156400000001,0.0020110329999999997,0.06375376,-0.00024323400000000002,0.09285723300000001,0.001426256,-0.536981912,-0.998108895,0.5213513679999999,1.386103663,-8.887957298,-8.440184196,-9.246274239,-9.206233192000001,-8.959856293,-8.587238571,-6.276364739,-1.171991946,-5.2425360679626465,-10.087272644042969,-6.407077789306641,-7.485456466674805,-9.243663787841797 -1967,1967,M127Q,-0.256329327,0.027999579,-0.013879313,0.016574106,-0.108822238,-0.098266145,-0.041613344,-0.47104531,,0.019542022,0.036457136,-0.033220814,0.005462189,0.014994394,0.018153817,-0.09121710400000001,-0.12642737199999998,1.3543633819999998,2.335204358,-4.675554074,-4.319172378999999,-4.351906929,-4.466376358,-5.373686371,-4.866628334,-4.433604645,0.9273366,-3.041135549545288,-7.799311637878418,-4.0855607986450195,-5.459505081176758,-6.876274585723877 -1968,1968,M127P,-0.127984832,-0.351675808,-1.493384021,-2.107462107,-2.891893956,-0.01092818,-0.047526513,-0.20844315,,-0.26252868100000004,-0.440822935,-1.5285009619999999,-1.45826708,-2.017809133,-2.1971150809999997,-2.960287068,-2.823500844,2.638841342,0.991786266,-11.22992623,-10.30533861,-11.53219071,-10.91125205,-12.19764767,-11.20320213,-9.761802929,-6.678452117000001,-9.636667251586914,-14.282859802246094,-12.720691680908203,-11.152074813842773,-13.588394165039062 -1969,1969,M127S,0.132158108,0.026204992000000003,-0.003291215,0.023630271,-0.5568486460000001,-0.041976245,0.007931769,0.256384446,,0.036167568,0.016242416000000003,-0.010460487,0.0038780579999999998,0.021432809,0.025827733,-0.368013059,-0.745684233,1.118565946,1.696697495,-7.777274414,-7.290417067999999,-6.921976044,-7.7006756670000005,-7.959889488,-9.013413802999999,-6.126012405,-1.5623317190000001,-5.368368148803711,-8.322331428527832,-5.553463935852051,-7.400304317474365,-9.689916610717773 -1970,1970,M127R,-0.142308791,0.024092656,-0.005452492,0.042037900999999996,-0.219904281,-0.047286935999999995,-0.042897912999999996,-0.241719669,,0.029194595,0.018990717,0.027573353,-0.038478337,0.023910643999999998,0.060165157000000004,-0.099496826,-0.340311735,1.4529047730000002,2.433234466,-6.314464351,-5.060274757,-6.377533347999999,-6.212635727,-8.903704277000001,-5.018173645,-4.621488605,0.517028536,-5.081457614898682,-10.216103553771973,-5.892822265625,-7.315446853637695,-8.404924392700195 -1971,1971,M127T,0.324975026,0.021246325,-0.049599325,0.010079181,-0.08453091800000001,-0.046856847,-0.050166609,0.7001166609999999,,0.049206442999999996,-0.006713793000000001,0.025256703999999998,-0.124455353,0.035222107999999995,-0.015063746000000001,0.007832779,-0.17689461399999998,1.187722774,2.755023382,-3.700639127,-5.050727287,-3.180319046,-3.347124123,-3.42329026,-3.501734917,-3.8604933439999995,0.40264946799999995,-4.923425197601318,-7.022912979125977,-4.448246955871582,-5.108972549438477,-8.526702880859375 -1972,1972,M127W,-0.152195719,0.022023213,-0.008344155,0.029861026000000002,-0.06086343599999999,0.015350743,-0.049791455,-0.25459998300000003,,0.027360687,0.016685738000000002,0.032160259,-0.048848567999999995,0.056516910999999996,0.00320514,-0.034595375,-0.087131496,1.4326555980000002,2.691098977,-6.2627130829999995,-5.540571922000001,-4.178261131,-5.468853988999999,-7.24382608,-8.882052292000001,-4.823903016,-0.820240052,-5.389353275299072,-10.210041046142578,-3.458228588104248,-7.695987701416016,-8.71391487121582 -1973,1973,M127V,0.250143235,-0.008310551999999999,-0.054514981,-0.024613634,-0.026401493999999998,0.00533881,-0.035189452999999996,0.535475923,,0.021807102999999998,-0.038428206,-0.0012979760000000002,-0.107731985,0.006691671,-0.055918938,0.02048114,-0.073284127,1.1759819329999999,2.606005258,-3.392381737,-2.669580376,-3.321936333,-3.078908966,-4.1309446030000005,-3.7605384060000002,-2.5070589659999998,1.5676711890000001,-4.40742826461792,-7.0809783935546875,-3.8558926582336426,-4.536397457122803,-7.958916187286377 -1974,1974,M127Y,-0.067259759,-0.031946522000000005,-0.06788897099999999,-0.029167727999999997,-0.200429175,-0.000187081,-0.084796651,-0.049722866,,-0.03564714,-0.028245903,-0.045668754000000006,-0.090109188,-0.04177736,-0.016558095,-0.116378629,-0.284479721,1.4412747909999999,2.315629562,-6.819694019,-5.883712425,-6.485792641000001,-6.890903542,-7.85604039,-6.982021095,-4.395572628,1.420604319,-1.7021989822387695,-5.757206916809082,-0.7626776695251465,-3.147810935974121,-4.754150390625 -1975,1975,S128A,0.016472111,-1.2515645309999999,-2.236337372,-2.114316659,-2.873953259,-0.10901291699999999,-0.061603724000000006,0.094547946,0.049411860999999994,-1.3205511540000001,-1.182577908,-1.993783158,-2.478891585,-2.178191303,-2.050442014,-2.764059806,-2.9838467110000004,0.18561698,-0.78568327,-9.651037715,-9.803297722,-9.69631546,-9.449031242,-9.864269669,-9.442274483,-8.776495975,-9.732748317999999,-9.756612777709961,-11.385354995727539,-10.87496566772461,-10.808938026428223,-14.68582820892334 -1976,1976,S128C,-0.11140495800000001,-1.6076112669999998,-1.99094189,-2.097380111,-2.662433669,-0.025056216,-0.032390652,-0.19041926399999998,-0.11310659099999999,-1.5685785419999998,-1.6466439919999998,-1.6757482080000001,-2.306135572,-1.773006176,-2.421754045,-2.212746644,-3.112120693,4.218314565,1.9792903919999998,-9.95241906,-9.875566727,-10.08568948,-9.893529465,-10.11184448,-9.795465149,-9.022567354,-11.21585505,-11.596345901489258,-11.822124481201172,-12.586225509643555,-11.867594718933105,-13.89120864868164 -1977,1977,S128E,-0.155754129,-1.722686105,-1.812883866,-2.653002795,-3.20795466,-0.06953229,-0.072499727,-0.23900853100000002,-0.200108315,-1.869608537,-1.5757636730000002,-1.800686944,-1.8250807869999999,-2.462216343,-2.8437892469999997,-3.18278342,-3.2331258999999997,-0.214970295,-1.170388274,-9.919787149,-10.02295014,-9.929194016,-9.915491486,-10.04593493,-9.685365173,-9.055072442,-11.57519656,-16.549705505371094,-16.6197509765625,-16.944860458374023,-16.658279418945312,-16.888805389404297 -1978,1978,S128D,-0.074296849,-1.719326006,-2.2787478880000003,-2.190200569,-2.807621802,-0.135373257,-0.0232954,-0.125298297,0.196626992,-1.853061984,-1.5855900269999998,-2.011384173,-2.546111602,-1.7186710619999999,-2.661730075,-2.564176876,-3.051066727,-0.7636379590000001,-1.043867321,-7.99417059,-8.391711548,-8.263399506,-7.706575043,-7.842781822,-7.766385033,-7.402024052000001,-7.494333591,-15.199918746948242,-14.860910415649414,-15.698783874511719,-16.75396156311035,-15.938770294189453 -1979,1979,S128G,-0.09230568800000001,-0.033182848,-0.455678036,-1.742475941,-2.500924977,-0.102192718,-0.035967221,-0.148644154,-0.067659977,-0.040500689,-0.025865006,-0.41759514700000006,-0.493760925,-1.5925274,-1.892424481,-2.564014674,-2.437835279,2.098901439,1.091643583,-5.303970528,-5.612216721,-5.315092239,-5.02618837,-5.510173515,-5.056181793,-5.463115737000001,-5.023569633,-9.046350479125977,-10.407155990600586,-12.072138786315918,-12.283361434936523,-16.340362548828125 -1980,1980,S128F,-0.11857652099999999,-1.498525991,-2.026254384,-2.565343318,-2.881734555,0.03679083,0.0053828,-0.242535842,-0.020923978,-1.7615395669999998,-1.235512415,-1.986808545,-2.065700222,-2.472246685,-2.65843995,-2.715692507,-3.047776602,-0.42379194299999995,-1.081604268,-10.01269843,-10.160211300000002,-10.0693588,-9.854657761,-10.20304729,-9.776217017999999,-9.055072442,-11.57519656,-15.088338851928711,-15.844135284423828,-17.000768661499023,-15.472362518310547,-16.402502059936523 -1981,1981,S128I,-0.12006068,-1.540195432,-2.122496059,-2.1844637380000003,-3.0404455980000002,0.054247400999999994,-0.04552592900000001,-0.19459543,0.008019176,-1.7419554519999998,-1.338435412,-2.025216376,-2.219775741,-2.0335332619999997,-2.335394214,-3.055130334,-3.025760862,-0.41913391299999997,-1.077378628,-9.969516109,-10.13907819,-9.935002235,-9.822947205,-10.12422798,-9.826324936,-9.055072442,-11.57519656,-15.040421485900879,-15.285003662109375,-17.525012969970703,-14.339086532592773,-17.988140106201172 -1982,1982,S128H,-0.14796089199999998,-1.610025019,-1.850737777,-1.991886702,-3.2458085710000004,-0.052833064000000006,-0.04611805099999999,-0.249803733,-0.064322646,-1.624536319,-1.595513718,-1.798652774,-1.902822779,-1.761212169,-2.222561235,-3.18074925,-3.310867892,-0.099821273,-1.0266550840000002,-9.939668703999999,-10.15204019,-9.894594437,-9.855421227,-10.04061165,-9.755676017999999,-9.055072442,-11.57519656,-15.1255521774292,-15.469844818115234,-15.967246055603027,-15.117266654968262,-16.426681518554688 -1983,1983,S128K,-0.112531175,-1.769479075,-2.201264704,-2.024671756,-2.380653616,-0.069100745,-0.069917138,-0.155145211,-0.302770657,-1.773036628,-1.7659215209999999,-1.9313588169999998,-2.471170591,-1.939675702,-2.109667809,-2.48415152,-2.277155712,-0.146076705,-1.13638157,-9.968428607,-10.10179744,-9.99029126,-9.926438393,-10.05288853,-9.770727417,-9.055072442,-11.57519656,-16.658267974853516,-17.564666748046875,-17.5384521484375,-12.149456024169922,-19.08572006225586 -1984,1984,S128M,-0.198782875,-1.511314354,-2.049144439,-2.088233373,-2.7541096119999997,-0.010537798999999999,-0.068827006,-0.32873874399999997,0.077440584,-1.5494947209999999,-1.473133986,-2.054604395,-2.0436844819999997,-2.01716379,-2.159302955,-2.9595796169999997,-2.5486396069999997,-0.419966313,-0.9698272640000001,-9.94414164,-10.13962422,-9.847012901,-9.833991989,-10.12719598,-9.772883102,-9.055072442,-11.57519656,-14.884946823120117,-17.682775497436523,-16.77210807800293,-13.596200942993164,-17.929931640625 -1985,1985,S128L,-0.184526395,-1.505193686,-1.8772706380000002,-2.309419662,-3.014886525,0.066557233,-0.077642374,-0.291410416,0.014258993999999999,-1.6087703690000001,-1.4016170019999998,-2.0547585919999998,-1.699782684,-1.90034818,-2.7184911439999997,-3.046883989,-2.98288906,-0.23280520600000001,-1.010719535,-9.981570526,-10.31303664,-9.966659691,-9.867466385,-10.06143769,-9.69925222,-9.055072442,-11.57519656,-13.600224494934082,-13.383447647094727,-17.756847381591797,-13.194758415222168,-16.25631332397461 -1986,1986,S128N,-0.081474372,-1.548084941,-1.979870571,-2.002247627,-2.858229487,-0.090487505,-0.039080575,-0.123868169,0.082724532,-1.52626488,-1.5699050019999998,-1.9856170640000002,-1.974124077,-1.9147527030000002,-2.08974255,-2.63531978,-3.081139194,-0.20482735,-0.93529136,-7.36925621,-7.715035149,-7.47119458,-7.370648468,-7.002819092,-7.286583762999999,-6.928677437999999,-6.962839144,-11.455702781677246,-13.482874870300293,-13.57443904876709,-12.095915794372559,-10.9114351272583 -1987,1987,S128Q,-0.102006272,-1.870261559,-1.864516557,-2.548003261,-2.952440127,-0.04512367900000001,-0.009388637,-0.19462390699999998,-0.06795693,-1.8414638319999999,-1.899059286,-1.969822797,-1.7592103159999999,-2.376079691,-2.71992683,-2.795616772,-3.109263482,-0.37151992799999994,-1.097881519,-9.926672137,-10.12087891,-10.04599197,-9.686287682,-10.1490668,-9.63113533,-9.019885811,-11.193242300000001,-16.174352645874023,-16.40667724609375,-13.432474136352539,-12.923240661621094,-19.082992553710938 -1988,1988,S128P,-0.039479091,-1.35787052,-1.96086749,-2.232399823,-3.027514885,0.023319289,-0.043320909000000005,-0.035637272000000005,-0.052150165,-1.369708446,-1.346032594,-2.007981179,-1.9137538,-2.192389323,-2.272410322,-2.9673140630000003,-3.0877157060000004,0.400492443,-0.828949044,-10.01514559,-10.14841965,-10.06400735,-9.807408492999999,-10.20840218,-9.847490257,-9.055072442,-11.57519656,-13.753524780273438,-15.115089416503906,-14.43716812133789,-14.085762023925781,-17.592784881591797 -1989,1989,S128R,-0.12132531699999999,-1.509393283,-2.037273473,-2.214769528,-3.158797018,0.0028081290000000004,-0.052069072,-0.19058156199999998,-0.083004859,-1.574435654,-1.444350911,-2.1669991000000004,-1.907547846,-2.0181925659999997,-2.41134649,-2.562668384,-3.754925652,0.096084474,-1.004895278,-9.787155513,-9.869352928,-9.948300483999999,-9.655300156000001,-9.939381119,-9.523442879,-8.941397563999999,-10.52730727,-15.743659973144531,-15.392539024353027,-16.977134704589844,-11.529516220092773,-18.000099182128906 -1990,1990,S128T,-0.068305479,-0.33444885,-1.458091985,-2.090616501,-2.4044379190000003,0.09943721900000001,-0.07572071400000001,-0.060890244,-0.021153703,-0.248630202,-0.42026749700000005,-1.49841133,-1.417772639,-2.0280531319999997,-2.15317987,-2.1871780690000002,-2.621697768,3.851672414,2.192045554,-7.460366035,-7.415571739,-7.518218642999999,-7.191391609,-7.696567062000001,-7.480081123,-7.55595057,-7.055243389,-9.925752639770508,-15.247709274291992,-10.0837984085083,-10.34384536743164,-12.756637573242188 -1991,1991,S128W,-0.16198607,-1.6363222830000002,-2.13909395,-2.161471007,-2.804468501,0.058580402999999996,-0.045422903,-0.278549237,0.031782372999999996,-1.520071792,-1.752572774,-1.9172760690000001,-2.360911831,-2.022502968,-2.300439045,-2.442040049,-3.166896952,-0.068443512,-0.932007817,-10.05523192,-10.26997732,-10.09023405,-9.873014656,-10.24041226,-9.802521324,-9.055072442,-11.57519656,-15.777196884155273,-18.119312286376953,-16.998720169067383,-18.45633888244629,-19.165504455566406 -1992,1992,S128V,-0.158187015,-1.438201099,-1.7194717309999998,-1.883499401,-2.9806117089999997,0.058885985999999994,-0.033843865,-0.282530165,-0.038957406,-1.477046857,-1.399355341,-1.70595012,-1.732993341,-1.9447159269999998,-1.822282875,-2.519154968,-3.4420684489999998,4.011122061,1.765720587,-9.925436668,-10.07316266,-10.002851199999998,-9.678073425,-10.110121000000001,-9.76297506,-9.055072442,-11.57519656,-13.675912857055664,-14.452849388122559,-16.28843879699707,-13.456419944763184,-16.366151809692383 -1993,1993,S128Y,-0.178490725,-1.687942789,-2.397879669,-2.426373953,-3.014799212,0.009939689,-0.087555083,-0.269426367,-0.12231459300000001,-1.642998485,-1.7328870930000002,-2.1023506690000002,-2.693408668,-2.043720765,-2.809027141,-2.831234631,-3.198363793,-0.030194923999999998,-1.046942645,-10.06943672,-10.17239769,-10.11911286,-9.94016629,-10.20241505,-9.913091697999999,-9.055072442,-11.57519656,-15.918036460876465,-16.034582138061523,-16.71977424621582,-14.802966117858887,-15.145177841186523 -1994,1994,D129A,-0.011829943999999998,-1.408450114,-2.601650206,-2.009108856,-2.712578003,0.055625159,-0.018910208,-0.00474968,-0.262690485,-1.591538649,-1.225361578,-2.363404775,-2.8398956369999997,-1.946800443,-2.071417269,-2.588533139,-2.836622867,0.17175854100000001,-1.122244889,-10.56151826,-11.8151782,-10.32455698,-10.95312377,-10.79195688,-8.922775459,-7.463094196,-6.754707786,-12.73313045501709,-15.405080795288086,-12.93426513671875,-15.230606079101562,-14.174720764160156 -1995,1995,D129C,-0.0038404409999999996,-0.36594841200000006,-1.459399925,-1.84969456,-2.466085328,0.124836252,0.023317966000000002,-0.030998848,-0.305725117,-0.38622226200000004,-0.345674561,-1.5663283540000001,-1.352471495,-1.994822061,-1.7045670590000002,-2.365487985,-2.56668267,3.6823781789999996,1.927697999,-10.97343627,-12.81853464,-10.19605974,-13.16457985,-9.489097267,-9.198909843,-7.172606021,-5.776755163,-13.170100212097168,-15.480393409729004,-13.109675407409668,-16.196657180786133,-13.641432762145996 -1996,1996,D129E,-0.024722137999999998,-0.437193203,-1.5673487019999999,-1.853781284,-2.5048827559999998,0.064984523,0.059846614000000006,-0.109290889,-0.17906249899999999,-0.373456915,-0.50092949,-1.43162978,-1.703067624,-1.693792065,-2.013770502,-2.054698152,-2.9550673589999996,3.870388548,2.327016199,-9.535917332,-10.44951384,-9.203647354,-9.52667952,-9.179198402,-9.320547546,-7.791659991,-7.043508257999999,-9.577827453613281,-12.524486541748047,-9.59894847869873,-10.361391067504883,-11.829999923706055 -1997,1997,D129G,-0.058882459000000005,-1.1061146179999999,-1.8097246319999998,-2.14584953,-3.1503486730000003,0.088618121,-0.002582539,-0.115182378,-0.385874494,-1.086667358,-1.125561877,-1.830504761,-1.7889445030000002,-2.162088455,-2.1296106040000002,-2.5607831030000003,-3.7399142419999998,3.5481144560000004,1.3491802290000001,-11.2020103,-12.00496219,-10.60032019,-11.85802313,-12.23805478,-9.3086912,-7.6890379289999995,-5.965991002000001,-12.061996459960938,-13.339439392089844,-13.334811210632324,-13.166816711425781,-13.454408645629883 -1998,1998,D129F,0.053410467999999996,-1.3992555219999998,-2.2390579440000002,-1.9581412390000001,-2.827106995,0.065587057,0.10134154699999999,0.005479389,-0.289550178,-1.3662185059999998,-1.4322925380000002,-2.480507313,-1.997608574,-1.90900102,-2.007281457,-2.881726935,-2.772487055,1.0295432820000001,-0.807698371,-14.74710385,-15.31029925,-13.58688738,-16.80798142,-15.44906331,-12.58128791,-9.671750758,-11.08690701,-14.588462829589844,-18.341941833496094,-19.259746551513672,-20.962509155273438,-18.961904525756836 -1999,1999,D129I,0.12195738199999999,-1.5106593990000001,-2.0427498440000003,-2.111318141,-2.718844525,0.087808753,0.09814143199999999,0.145773331,-0.093117024,-1.394646214,-1.6266725830000002,-1.990421081,-2.095078606,-2.117884793,-2.1047514880000002,-2.8687619580000003,-2.568927091,0.431829843,-0.842943867,-13.67906109,-15.27736082,-12.37789369,-14.26754964,-14.13182085,-12.34068046,-9.671750758,-11.08690701,-14.565715789794922,-19.416908264160156,-18.25568962097168,-19.38861083984375,-19.1708984375 -2000,2000,D129H,0.10976663099999999,-1.2483044970000001,-1.9771825440000002,-2.196265839,-2.914716598,0.0826177,0.103060645,0.116472616,-0.347542125,-1.4837961430000002,-1.0128128509999998,-2.297054954,-1.6573101330000002,-2.026578657,-2.36595302,-2.999304572,-2.8301286230000002,0.9703119729999999,-0.9260675979999999,-11.32043294,-12.82869043,-10.03161928,-12.63614774,-11.21814159,-9.887565689,-7.693112642999999,-6.096182002999999,-12.777527809143066,-15.910869598388672,-15.676857948303223,-15.860458374023438,-14.348234176635742 -2001,2001,D129K,-0.079646051,-1.316888882,-2.209058979,-2.039066649,-2.79710803,0.092081506,-0.025925852000000003,-0.133366249,-0.358431467,-1.4623979980000001,-1.171379766,-2.079362164,-2.3387557930000002,-2.030734617,-2.04739868,-2.7816117819999997,-2.8126042780000002,3.347442364,0.8203826759999999,-12.89603935,-13.73127371,-12.82347176,-13.90686343,-12.62764559,-11.39094226,-8.729112257999999,-8.173907681000001,-14.712894439697266,-19.58643341064453,-17.417551040649414,-17.567598342895508,-18.128755569458008 -2002,2002,D129M,-0.005799360999999999,-1.744514476,-2.228149914,-2.296718212,-2.515168971,0.100907186,0.037297117000000005,-0.048895839,-0.236978513,-2.205675426,-1.283353525,-2.1024802890000003,-2.353819539,-2.229944001,-2.3634924219999998,-2.503699912,-2.526638029,-0.098573958,-1.237680814,-13.76827873,-15.37322535,-12.93097838,-14.58922565,-14.17326154,-11.77470274,-9.671750758,-11.08690701,-15.730863571166992,-19.32308578491211,-18.512922286987305,-19.508317947387695,-19.894506454467773 -2003,2003,D129L,-0.023379842999999997,-1.3406553270000001,-1.904621968,-2.177875,-3.197355755,0.09824696599999999,0.019536401000000002,-0.06629608599999999,-0.309047968,-1.3872000580000001,-1.294110595,-1.9267520009999999,-1.8824919340000001,-2.024252489,-2.331497511,-2.996978405,-3.397733105,3.446687315,1.058825631,-14.00906497,-15.46476691,-13.12358035,-14.8103076,-14.30693511,-12.33973488,-9.671750758,-11.08690701,-13.426492691040039,-18.30252456665039,-18.99770164489746,-18.771146774291992,-20.19081687927246 -2004,2004,D129N,0.052958175,-0.867696536,-1.8813856569999998,-2.012423323,-2.770464705,0.050656662000000005,0.020455176999999998,0.08546117199999999,-0.085430195,-0.876132274,-0.859260798,-1.891036449,-1.871734865,-2.143438897,-1.8814077480000002,-2.894316063,-2.646613346,2.9459409260000005,0.9121094340000001,-8.919320782,-8.771351852,-8.27338649,-9.257446547999999,-10.03939047,-8.255028549,-6.651229801,-5.264599277,-10.840385437011719,-13.35345458984375,-11.937469482421875,-11.382063865661621,-11.616585731506348 -2005,2005,D129Q,0.038189192000000004,-1.385652814,-2.005788889,-2.3129178130000003,-2.9204441969999997,0.094676408,0.09512320699999999,-0.018744824,-0.410593871,-1.5539129790000001,-1.217392648,-2.103930356,-1.9076474209999998,-2.231394068,-2.394441558,-2.982271233,-2.858617161,1.044908728,-1.000397661,-13.91128219,-15.35845213,-13.10743671,-14.05901527,-14.96308458,-12.06842224,-9.632368373,-10.79873915,-14.212220191955566,-17.865833282470703,-15.273086547851562,-15.798392295837402,-16.78526496887207 -2006,2006,D129P,0.017618805,-1.4610978369999998,-1.993188282,-2.333790601,-3.018767965,0.073897677,0.015432443999999998,0.019805165,-0.23109149899999998,-1.574481414,-1.347714259,-1.927218233,-2.05915833,-2.2977199930000003,-2.369861209,-2.80555911,-3.23197682,0.461090977,-1.0202539259999999,-13.65381118,-14.7681695,-12.80506709,-14.36339105,-14.11708393,-12.21534432,-9.608956381,-10.82145565,-16.207796096801758,-19.484899520874023,-18.76822280883789,-19.219310760498047,-19.821407318115234 -2007,2007,D129S,0.011819596000000002,-0.61259896,-1.8424749040000001,-2.4110432,-3.129493959,0.06775876,0.018533021,0.00510617,-0.175096311,-0.616647374,-0.608550545,-2.035896471,-1.649053336,-1.987268923,-2.834817477,-2.959994838,-3.29899308,1.56681955,-0.082826669,-10.57576444,-11.77745882,-10.99855804,-9.922616646,-11.21231445,-8.967874245,-6.371061183999999,-3.128094537,-12.54942512512207,-14.395724296569824,-12.049755096435547,-13.383769989013672,-13.997118949890137 -2008,2008,D129R,0.028375638999999998,-1.43260327,-2.058856573,-2.12742487,-2.671514636,0.100741895,0.067515669,-0.010764392,-0.425023586,-1.539563953,-1.325642587,-1.9646425930000002,-2.153070553,-2.092106305,-2.162743435,-2.871012194,-2.472017078,3.614472057,1.029570397,-14.217889600000001,-15.762962599999998,-13.09037613,-15.42272258,-14.30651825,-12.50686844,-9.671750758,-11.08690701,-14.718538284301758,-18.389278411865234,-18.070966720581055,-18.758766174316406,-18.6849422454834 -2009,2009,D129T,-0.015180192,-1.419740759,-1.994788519,-2.236750559,-2.844276943,0.077110372,0.000484728,-0.030845112,-0.341232651,-1.7009944609999998,-1.138487057,-1.9847439480000002,-2.004833089,-2.061055137,-2.41244598,-2.510902307,-3.1776515780000003,3.8457341210000004,1.195650811,-13.54016954,-15.12629653,-13.28578957,-13.69442089,-13.87408803,-11.720252699999998,-9.418473075,-9.658783954,-14.347173690795898,-19.452312469482422,-15.644112586975098,-16.210195541381836,-17.601591110229492 -2010,2010,D129W,-0.052357805,-1.337561941,-2.0680788430000003,-2.7387071310000004,-2.957157889,0.071735078,0.012185782,-0.11690139199999999,-0.355725574,-1.339991598,-1.3351322829999999,-2.08958133,-2.046576355,-2.819105033,-2.658309229,-3.0928609430000003,-2.821454835,1.532020746,-0.61031982,-14.21796215,-15.16858621,-12.8766331,-15.66458355,-14.89324905,-12.48675885,-9.671750758,-11.08690701,-15.072039604187012,-20.688640594482422,-20.74561309814453,-21.925060272216797,-20.783554077148438 -2011,2011,D129V,0.013005406,-1.4261294340000001,-1.782516038,-2.0350727280000003,-2.793114109,0.09568984900000001,0.037791967,-0.011781155,-0.30952918,-1.625361775,-1.226897093,-1.7825787830000002,-1.7824532919999998,-2.27801928,-1.792126175,-2.3756839309999997,-3.210544286,0.718500721,-1.028588993,-13.23629935,-15.05665861,-11.9137488,-13.66788264,-13.89113586,-11.65207081,-9.671750758,-11.08690701,-13.300605773925781,-17.473543167114258,-15.732933044433594,-16.875404357910156,-17.595890045166016 -2012,2012,D129Y,-0.004803197,-1.808920774,-1.807537824,-2.060094514,-2.8181358960000003,0.066177267,0.052046555,-0.061652948,-0.600340011,-1.744944588,-1.872896959,-1.5748026609999999,-2.0402729859999997,-2.246334417,-1.87385461,-2.821120324,-2.8151514669999997,3.694833543,0.988652786,-15.01357392,-16.01895072,-14.24526814,-16.98064385,-15.313285,-12.50972189,-9.567958051,-10.36663755,-12.728021621704102,-17.13799285888672,-17.550312042236328,-17.782541275024414,-14.53674602508545 -2013,2013,N130A,0.009842616,0.020782053999999998,-0.395557714,-1.8189424509999998,-2.656971339,-0.093669078,-0.053254894000000004,0.072940125,-0.067322639,0.021797802999999998,0.019766305,-0.35209011700000004,-0.43902531,-1.8235589490000002,-1.8143259530000002,-2.6294382730000003,-2.6845044039999997,1.467109165,0.751625439,-12.98354641,-12.19228654,-11.38029607,-14.21973334,-13.31074714,-13.81466898,-9.806692222,-9.203411388,-11.329082489013672,-13.735090255737305,-9.803208351135254,-13.043254852294922,-11.988353729248047 -2014,2014,N130C,0.024398517,0.109672713,-0.050340777,-0.02844622,-1.7461178609999999,-0.0035371459999999997,0.004808529000000001,0.043988505,0.053981812000000004,0.143180268,0.076165157,-0.039203664,-0.06147789,0.007428542,-0.064320981,-1.7698773019999998,-1.722358419,0.753028571,1.310198095,-12.80348507,-12.10647131,-11.436971400000001,-13.71755447,-13.38781839,-13.36860976,-10.20320526,-11.01779993,-12.177324295043945,-12.790366172790527,-10.94825553894043,-13.894891738891602,-12.954111099243164 -2015,2015,N130E,0.075540251,-0.506865954,-1.962355764,-2.385359875,-2.9601839560000003,-0.013509055,-0.08914534199999999,0.240225844,-0.030693744,-0.40078998200000004,-0.612941926,-1.87104568,-2.053665847,-2.176943011,-2.593776739,-2.890068282,-3.030299629,1.333622985,-0.018033341,-11.29058329,-10.4095993,-10.46944112,-11.5241302,-12.29480589,-11.75493994,-9.128649847,-7.5386653720000005,-14.514419555664062,-15.234125137329102,-10.33260726928711,-17.397661209106445,-13.645169258117676 -2016,2016,N130D,-0.041373187,0.031127541,-0.063908363,-1.266128135,-1.95476231,-0.080367095,-0.074078273,-0.008668101,-0.0641175,0.017088067,0.045167015,-0.036439556,-0.09137716900000001,-0.9085584529999999,-1.623697816,-1.7871560069999999,-2.122368613,2.355137864,1.728763865,-9.102836044,-7.944507446,-8.510061836,-9.471690636,-10.27161156,-9.316308746,-8.196794015,-6.134887279,-12.152734756469727,-13.030241966247559,-10.224762916564941,-13.766294479370117,-12.605705261230469 -2017,2017,N130G,-0.024233236000000002,0.04455197599999999,-0.039669193,-0.46562501,-2.413504986,-0.034404377,-0.05670689,0.008240418000000001,0.134250154,0.077153023,0.011950928000000001,-0.007814877,-0.071523508,-0.374706661,-0.556543358,-2.247677999,-2.579331972,1.423129076,1.3201015520000001,-9.600162699999998,-9.148767822,-7.414082024,-9.750855117999999,-11.36770308,-10.31940546,-6.361967029,-3.478570945,-9.113090515136719,-10.476259231567383,-3.7727489471435547,-9.076138496398926,-10.917461395263672 -2018,2018,N130F,-0.044510355,-1.682379431,-1.874811332,-2.18077384,-2.968582287,-0.056659869,-0.050862265,-0.038158444,-0.170572831,-2.017103653,-1.3476552080000002,-1.8330758280000001,-1.916546836,-2.205919948,-2.1556277319999997,-2.74295396,-3.194210613,-0.059893058,-1.16293563,-13.17195755,-12.61592044,-12.67158208,-13.22929736,-13.4082211,-13.93476675,-10.20320526,-11.01779993,-17.173355102539062,-17.119535446166992,-16.110897064208984,-19.40277671813965,-16.677371978759766 -2019,2019,N130I,-0.06532156900000001,-1.25755066,-1.725859997,-1.97277285,-3.032615318,-0.012702834,-0.06922955900000001,-0.061413577999999996,0.36269863700000005,-1.258223287,-1.256878032,-1.6928971240000001,-1.75882287,-1.880695143,-2.064850556,-2.961797199,-3.103433437,3.295135625,1.283762523,-13.05782475,-12.07880782,-13.04095367,-14.51217242,-12.72139012,-12.93579974,-9.972288303,-9.640872774,-13.615333557128906,-15.852071762084961,-13.706111907958984,-17.539064407348633,-14.350320816040039 -2020,2020,N130H,0.033708557,-0.845477885,-1.72417433,-2.021344251,-3.198228322,-0.032492802,-0.000551363,0.067968477,0.18607548,-0.8913066629999999,-0.799649107,-1.7722470609999998,-1.676101598,-1.864264572,-2.178423929,-3.1794498339999997,-3.21700681,3.108949663,1.190642147,-9.825878551,-9.0770121,-10.37934066,-9.991969894,-10.537751400000001,-9.143318703,-8.891296147,-7.847138651,-12.256502151489258,-13.072799682617188,-11.237740516662598,-15.8649320602417,-13.336742401123047 -2021,2021,N130K,0.043483192000000004,-1.357394064,-1.8949240059999999,-1.977307498,-2.376040319,-0.014983327,-0.086058395,0.173024779,0.288065018,-1.2632209779999999,-1.45156715,-1.4014124469999998,-2.388435564,-1.80421979,-2.150395205,-2.466192539,-2.285888099,3.94734505,2.100943203,-9.518858356,-9.123144684,-9.033809555,-9.057015305,-10.32828936,-10.05203288,-8.619667813,-7.34346731,-11.225027084350586,-13.889670372009277,-12.281778335571289,-13.863520622253418,-12.538151741027832 -2022,2022,N130M,-0.046735915,-0.282326592,-1.5084988030000002,-2.240817461,-2.9265659160000004,-0.025133531,-0.056008922,-0.037462907999999996,0.191155005,-0.196990649,-0.367662535,-1.5893565319999998,-1.427641074,-2.061585285,-2.420049636,-2.69552931,-3.157602522,2.6016566290000003,0.9724679740000001,-13.26129156,-12.0830046,-12.23582504,-15.28310062,-13.05174718,-13.65278037,-10.20320526,-11.01779993,-14.345499992370605,-16.46552848815918,-14.692523956298828,-15.546212196350098,-14.847156524658203 -2023,2023,N130L,-0.061197303,-0.145357151,-1.6567672830000002,-2.3110628159999997,-3.026300201,-0.011388816999999999,-0.077565649,-0.044828955999999996,0.032792512999999995,-0.06443344299999999,-0.226280858,-1.58869992,-1.724834646,-2.135331344,-2.486794288,-2.58521518,-3.467385222,0.672870245,0.016609234,-13.31213448,-12.38581644,-12.38808017,-15.52882551,-12.91444947,-13.34350081,-10.20320526,-11.01779993,-12.812884330749512,-16.264995574951172,-15.50208568572998,-17.312957763671875,-14.901924133300781 -2024,2024,N130Q,0.080382455,0.067851833,-0.03985369,-1.45297514,-2.8405697639999996,-0.09346985199999999,-0.024992275,0.185757185,0.09773332,0.087780114,0.047923552,0.017892537,-0.097599917,-1.274069015,-1.631881265,-3.089856628,-2.5912829,0.609229399,0.7150416940000001,-10.82362021,-10.06617358,-10.42454898,-11.36405898,-11.09258118,-11.17073836,-8.921545175,-7.475800759,-12.839591979980469,-14.003755569458008,-11.662904739379883,-14.905545234680176,-14.970260620117188 -2025,2025,N130P,-0.00103399,-0.855582924,-1.8027762859999998,-2.130373139,-3.224951491,0.037335375,-0.072071789,0.07000381,0.10827761400000001,-0.8486937109999999,-0.862472136,-1.787728617,-1.817823955,-2.01820485,-2.242541428,-2.770838663,-3.679064318,3.209742597,1.256410713,-13.48429045,-12.61478319,-12.27783862,-14.80128957,-13.78832182,-13.93921903,-10.14242229,-10.76554452,-12.209216117858887,-15.319809913635254,-12.867256164550781,-16.2668399810791,-14.33877944946289 -2026,2026,N130S,0.021364942,0.074347767,0.00060289,-0.021363454,-1.617914446,-0.09920153599999999,-0.013080459,0.055810343,-0.022724814,0.06712971400000001,0.08156582,0.020918333,-0.019712553,0.013989796,-0.056716703,-1.725102996,-1.510725895,0.6955947809999999,1.310974656,-7.483133296,-7.113253471,-4.955581055,-8.85895166,-8.425829193,-8.062051102,-6.931667112,-4.081639419,-10.551456451416016,-9.855283737182617,-8.756645202636719,-10.110469818115234,-9.1860933303833 -2027,2027,N130R,-0.036261699999999994,-1.257133593,-1.883533601,-1.9680556980000001,-3.191577633,-0.065587718,-0.060221240999999995,-0.012302158999999998,0.034459672999999996,-1.3251700770000001,-1.189097109,-1.725081808,-2.041985394,-1.947641933,-1.9884694619999999,-2.727713993,-3.655441273,3.8660255169999997,1.7222579059999998,-10.32228416,-9.107186667999999,-11.10508169,-10.31290812,-10.64531119,-10.44093311,-8.479675992999999,-7.487590025,-15.250950813293457,-15.272774696350098,-12.94767951965332,-16.31696319580078,-14.757468223571777 -2028,2028,N130T,-0.05860724900000001,0.017226658,-0.697481475,-1.7778530959999999,-3.1448427889999997,-0.00885697,-0.067965277,-0.049249220999999996,0.15729673800000002,0.043250172999999996,-0.008796857,-0.717848879,-0.677114071,-1.637705424,-1.9180007680000002,-2.731041937,-3.55864364,2.07927183,1.022977183,-9.676923064,-8.969382713,-7.329405746,-11.31274644,-10.03719245,-10.73588797,-8.251362366,-6.640448038,-12.50163745880127,-14.34243392944336,-9.278910636901855,-12.71269416809082,-10.85735034942627 -2029,2029,N130W,-0.024835813999999998,-1.3103437390000001,-1.855493663,-2.150861522,-3.060188993,-0.06368613,-0.059137922999999995,0.009466295999999999,0.183329668,-1.261665534,-1.3590219430000001,-1.636945719,-2.0740416059999998,-2.310819835,-1.9909032080000002,-2.8478538469999997,-3.272524138,3.0423158960000003,0.9658634290000001,-13.1561764,-12.37614291,-12.82886566,-13.91650491,-13.46400338,-13.19536515,-10.20320526,-11.01779993,-17.125349044799805,-18.77607536315918,-16.838134765625,-19.760761260986328,-18.811399459838867 -2030,2030,N130V,-0.017208553,-0.513993003,-1.647175244,-2.0199940830000003,-2.6511703030000002,-0.019462686,-0.031363065,-0.00305404,-0.012964976999999999,-0.526614871,-0.501371134,-1.617706361,-1.6766441269999999,-2.078505652,-1.961482514,-2.682486453,-2.619854153,2.9582135689999998,1.173828442,-13.47061243,-12.36999066,-13.30877235,-14.88097434,-13.15816711,-13.63515768,-10.20320526,-11.01779993,-13.596498489379883,-15.415340423583984,-11.551824569702148,-15.73875617980957,-15.143467903137207 -2031,2031,N130Y,-0.058959356,-1.4263187259999999,-1.6778002840000001,-1.942094189,-2.880417633,-0.001114889,-0.02817506,-0.089743651,-0.11495451599999999,-1.527669449,-1.324968003,-1.5866796719999998,-1.768920895,-1.927339109,-1.956849268,-2.5893118569999998,-3.1715234089999997,4.114951448,1.902815074,-12.583025099999999,-11.84163783,-12.72054424,-12.38801036,-13.37711244,-12.58782061,-9.485482959,-8.173117226,-14.941577911376953,-17.099262237548828,-15.689931869506836,-17.949630737304688,-14.736879348754883 -2032,2032,T131A,0.048297398,0.004449922,0.02299577,-0.029260658,-0.057694497000000004,-0.012444213,0.04212975099999999,0.054465044000000004,-0.056604423,-0.071647707,0.080547551,-0.035675032999999995,0.08166657299999999,-0.065340446,0.006819131,-0.080458732,-0.034930261000000004,1.514398944,2.4542898999999996,-4.246565831,-6.6098541410000005,-2.666873261,-4.6183227460000005,-4.677796371,-2.659982636,-5.073301823,-1.70212163,-7.272420883178711,-7.189986228942871,-8.063720703125,-7.010643005371094,-9.13159465789795 -2033,2033,T131C,0.013286748999999999,-0.008771147,0.012372812,0.01915539,-0.28010519300000003,0.070015408,-0.0006570139999999999,0.027230511000000002,0.051342263,-0.026297281000000002,0.008754986999999999,-0.028427311,0.053172934000000005,0.009204986,0.029105792999999998,-0.233781008,-0.326429378,1.159418384,1.867914336,-8.927557831,-10.38276093,-8.135883308,-8.573146202,-9.710283585,-7.835715126,-7.96272109,-4.885169463,-11.350695610046387,-11.392536163330078,-10.967002868652344,-7.387640953063965,-11.9097900390625 -2034,2034,T131E,0.014478833,0.04320562,-0.68795339,-2.074980318,-2.26700351,-0.02890722,0.043174524000000006,-0.014216858999999998,-0.012240498999999998,-0.039854104,0.126265343,-0.337759154,-1.038147626,-1.152091357,-2.9978692789999997,-1.7959030480000002,-2.738103971,3.10804231,2.2674934230000003,-10.92003821,-11.98953738,-9.782994125,-12.53009324,-11.31500587,-8.982560417,-8.066085602000001,-4.236736375,-11.769132614135742,-16.773033142089844,-13.883633613586426,-11.600423812866211,-13.773975372314453 -2035,2035,T131D,-0.094024934,-0.35089954700000003,-1.191625028,-1.8809662169999999,-2.363424755,0.06999575799999999,-0.051876448,-0.136173419,-0.137672152,-0.14479698800000002,-0.557002106,-1.236823776,-1.14642628,-1.795152953,-1.9667794809999999,-1.71880534,-3.0080441689999997,4.089583049,2.678782411,-11.69234144,-14.42583477,-11.90158421,-14.36455279,-10.79145442,-6.978280998,-8.54861227,-5.05816539,-11.270734786987305,-15.707714080810547,-13.194809913635254,-12.16708755493164,-14.534967422485352 -2036,2036,T131G,0.047606494000000006,0.013551701000000001,0.012045051000000001,0.03017478,-0.0515058,-0.024579447999999997,0.042201062000000004,0.053011925,4.09e-05,-0.062548746,0.089652148,-0.02412637,0.048216472,0.012509791000000001,0.047839768,-0.064465288,-0.038546311,1.461429717,2.542843565,-7.088991402,-8.60154879,-4.817755928,-8.218120277,-8.63810849,-5.169423523,-6.01476389,-3.3945295339999997,-10.525976181030273,-11.098285675048828,-9.092639923095703,-8.159245491027832,-10.969408988952637 -2037,2037,T131F,0.0014948589999999999,0.052081815,0.04874863,-0.095103385,-1.8673641769999998,0.060898747,0.014406205,-0.011416488,0.10455611,-0.047708494000000004,0.151872124,-0.017418749,0.11491600800000001,0.021557932999999998,-0.211764702,-1.442284844,-2.292443509,0.81676416,1.333682387,-10.59671192,-13.56747997,-9.515429122999999,-10.23048791,-12.20748679,-7.462675827000001,-7.770374587999999,-4.868697549,-12.653463363647461,-17.482131958007812,-13.317161560058594,-10.347223281860352,-14.003530502319336 -2038,2038,T131I,0.002171054,-0.122951715,-1.20479453,-2.222924378,-2.899965958,-0.022934467000000004,0.048435571,-0.044093464000000006,0.02428686,-0.082489638,-0.163413792,-1.013969286,-1.395619774,-1.952979466,-2.49286929,-2.5668279330000003,-3.233103983,2.619610036,1.224999762,-9.405303828,-10.57299089,-8.578396675,-9.376633803999999,-11.77050418,-6.727993591000001,-7.51698672,-3.431465041,-10.501907348632812,-14.742390632629395,-10.827536582946777,-8.427899360656738,-12.531517028808594 -2039,2039,T131H,0.028226936,0.02463272,0.058249780999999994,-1.14772423,-1.881907864,0.02076724,0.058959530999999996,-0.00250566,0.001041058,0.011361658,0.037903782000000004,0.022919771000000002,0.093579791,-1.0059000820000001,-1.2895483779999999,-2.306129426,-1.457686302,1.9801443930000002,1.328163266,-12.43942887,-16.253795,-10.80072688,-12.38720581,-12.06989527,-10.68552142,-9.067932449,-5.568424604,-12.590269088745117,-17.231035232543945,-12.915435791015625,-10.928362846374512,-14.024179458618164 -2040,2040,T131K,-0.058575127000000005,-0.028344682000000003,-1.106862664,-1.834230874,-2.769964672,0.04038543,-0.06423854400000001,-0.05291171,-0.047411891,-0.08216411900000001,0.025474756,-0.92262283,-1.291102497,-1.8152229359999998,-1.8532388119999998,-2.265214601,-3.274714742,3.302068293,1.9418659569999999,-13.56810852,-14.729556500000001,-14.68345431,-13.33579398,-13.23829883,-11.85343899,-10.32832796,-7.642594571,-12.72110366821289,-15.782343864440918,-14.148887634277344,-11.044188499450684,-12.920785903930664 -2041,2041,T131M,0.021392737000000002,0.066812967,0.063199091,-0.015479573,-2.2853065790000002,0.001275874,0.053564499,-0.010779025,0.012610228000000001,0.031158667,0.10246726699999999,0.049264407,0.077133774,0.073005109,-0.103964255,-1.7378552530000002,-2.8327579039999997,0.6190730179999999,1.306643808,-9.861472601000001,-12.29019492,-8.348089005,-9.240649178,-11.69247783,-7.73595208,-8.220714059,-4.712211831,-10.055305480957031,-13.612875938415527,-11.278009414672852,-8.572075843811035,-11.903228759765625 -2042,2042,T131L,0.022006502,0.034902455,0.035972631,0.04639541,-1.456442477,0.042640594000000004,0.018568335,0.025444667999999997,-0.02323047,-0.033005957,0.102810866,-0.007412929,0.079358191,0.06070085,0.03208997,-1.392526659,-1.520358294,0.650505043,1.32569687,-8.174373665,-10.80712489,-6.380018967000001,-6.944152206,-10.76862739,-5.9719448779999995,-6.86075613,-2.594168944,-10.388450622558594,-15.617260932922363,-11.107267379760742,-8.909881591796875,-12.808551788330078 -2043,2043,T131N,0.052592318,0.081785523,0.06686613,-1.2196547229999999,-2.0954179969999998,0.01203924,0.049016871,0.056167765,-0.02008759,-0.061074337,0.224645383,-0.051201870999999996,0.18493413,-1.206410527,-1.2328989190000001,-1.938948782,-2.2518872119999997,2.661051326,1.8435594119999998,-10.06126338,-13.27005539,-9.455758162999999,-12.503653199999999,-8.562573181,-6.514276962,-8.906852995,-2.284009593,-8.879716873168945,-12.685572624206543,-10.018987655639648,-8.064712524414062,-10.466462135314941 -2044,2044,T131Q,0.052493263,0.065880434,-0.20387656899999998,-1.434802519,-3.027916002,-0.021407805,0.093950274,0.011036252,0.00503871,0.00893029,0.122830577,-0.140835973,-0.266917165,-1.320855732,-1.548749305,-2.8530341530000003,-3.20279785,1.076757593,0.7619866829999999,-12.04628926,-13.36329772,-10.75826996,-13.00881847,-12.42807006,-10.67299008,-9.025999967999999,-5.538630082999999,-11.999288558959961,-16.285947799682617,-12.686884880065918,-9.856451034545898,-13.554317474365234 -2045,2045,T131P,-0.002501147,0.017751106000000003,-0.067160285,-1.437859926,-2.281962266,0.030246559,0.025453949,-0.030456242999999997,-0.032146624,-0.02667684,0.062179051,-0.025140923,-0.10917964599999999,-1.320431939,-1.5552879130000001,-2.31841307,-2.245511462,0.434296412,0.701866598,-7.53475773,-9.945623276000001,-5.960029106,-7.604709053,-9.026103187999999,-5.137324028,-7.20415787,-3.51864778,-10.107358932495117,-11.082063674926758,-10.019783020019531,-9.375165939331055,-10.910663604736328 -2046,2046,T131S,0.046852555,0.032947322,0.07451319099999999,0.031751946,-0.001675894,-0.038013249,0.046399272000000005,0.047305837,0.028249964,-0.03163583,0.097530474,0.043441285999999996,0.10558509599999999,0.004992831,0.05851106,0.000939062,-0.004290849,1.248566977,2.72936441,-3.821205298,-4.472364311000001,-3.18822287,-4.050491608,-4.644079247,-2.750868454,-4.463425473,-2.522269712,-6.710078716278076,-7.007205009460449,-6.986213207244873,-6.502480506896973,-6.9818267822265625 -2047,2047,T131R,0.050172972999999996,0.039187439,-1.13788643,-1.812974307,-2.1567568969999997,0.005204788,0.06707830099999999,0.033267644,-0.038858987000000005,-0.02052667,0.098901548,-0.9822600570000001,-1.293512803,-1.559894389,-2.066054225,-2.1245248340000003,-2.188988959,3.628021564,2.358921315,-12.75870828,-14.96183696,-10.28337519,-13.48510148,-12.98279372,-12.08043405,-9.342256839,-5.9166558810000005,-13.331546783447266,-15.748945236206055,-13.101462364196777,-9.08547306060791,-13.726583480834961 -2048,2048,T131W,0.021055777,-0.002815329,-0.085255308,-1.4243991569999999,-2.299041508,0.01387109,0.040213791,0.001897762,-0.003721882,-0.061463957,0.055833299,-0.055846379,-0.11466423699999999,-1.303434223,-1.545364091,-2.0383263830000002,-2.559756632,2.581354826,1.712923916,-12.75646131,-15.22410963,-11.18275576,-12.99697552,-13.64308494,-10.73538071,-9.800797657,-6.314157085,-14.38941764831543,-18.092666625976562,-15.909828186035156,-13.127228736877441,-16.711936950683594 -2049,2049,T131V,0.007907616,0.038888167,0.08239005099999999,0.069681459,-1.578518336,0.007673937,0.016066771,-0.00025154,-0.033384935,0.01560534,0.062170994,0.05916744400000001,0.10561265800000001,0.123954756,0.015408161,-1.529645828,-1.627390844,0.13042873800000002,1.299862708,-6.790883974,-8.165201324,-5.51369799,-6.767639915,-9.373176628,-4.13470401,-5.90168151,-2.6747125819999997,-9.477728843688965,-12.126453399658203,-9.576532363891602,-7.519129753112793,-12.141938209533691 -2050,2050,T131Y,0.11888805599999999,0.057136108,0.052911575999999995,-0.6959789740000001,-1.8470273240000001,-0.005336982,0.12290350300000001,0.114872608,-0.00513964,-0.073755368,0.188027584,-0.065046197,0.17086934899999998,-0.34613763700000005,-1.04582031,-1.808615013,-1.8854396340000001,1.520045735,1.3883950569999999,-11.48385724,-15.21080721,-10.45551006,-11.23754785,-11.73262743,-8.782793677999999,-8.30285788,-4.266752662,-11.842992782592773,-17.73644256591797,-13.845494270324707,-10.396466255187988,-14.071823120117188 -2051,2051,A132C,-0.006064091,0.029966262999999996,-0.501014401,-1.437874555,-2.939642149,0.018458061,0.025583765,-0.037711947,0.012604995,0.097407365,-0.03747484,-0.237032501,-0.7649963009999999,-1.41100089,-1.464748219,-2.736940785,-3.142343512,1.327313557,0.8034763559999999,-5.853107501,-6.582799026,-3.7893286510000004,-5.651686347999999,-8.773572342000001,-4.4681511380000005,-5.49571702,-4.022096908,-11.09929370880127,-12.078566551208496,-10.624321937561035,-11.03986930847168,-11.138351440429688 -2052,2052,A132E,0.114228499,-1.43646584,-1.591899839,-1.785240095,-2.062191363,0.03875047,0.147340431,0.081116567,-0.00365282,-1.673624145,-1.199307535,-1.7086104030000002,-1.475189275,-1.9468196880000002,-1.623660501,-2.545760855,-1.578621871,-0.04555221,-1.003656415,-10.51240111,-10.21643024,-10.50315656,-10.11584777,-11.10218322,-10.62438775,-9.72973559,-10.89818902,-16.03076934814453,-18.51961326599121,-15.466920852661133,-17.624120712280273,-16.670429229736328 -2053,2053,A132D,0.123345169,-1.4248093169999998,-1.939286464,-2.453659296,-2.770201187,0.03346145,0.18536128899999998,0.061329048,-0.077310373,-1.607088424,-1.24253021,-1.943104678,-1.93546825,-2.005222705,-2.9020958869999998,-2.604163871,-2.936238503,-0.037436219,-1.024809728,-10.84490336,-10.55430067,-10.95464105,-10.59341626,-11.3753049,-10.74685392,-9.72973559,-10.89818902,-16.477354049682617,-18.135732650756836,-16.7835693359375,-16.682418823242188,-17.290760040283203 -2054,2054,A132G,0.012875998,0.032919828,0.029576208,-0.9510449320000001,-1.8247725430000001,0.029134626,0.025100992000000003,0.000651003,-0.0017208070000000002,0.07946679799999999,-0.013627142,0.017328293999999998,0.041824122000000005,-0.477978561,-1.4241113019999998,-2.046956504,-1.602588581,1.65032148,1.369195617,-4.981527443,-3.399084785,-6.03902446,-4.401973328,-4.556239304,-6.511315337999999,-4.8129852810000004,-2.992713268,-8.5007963180542,-8.731147766113281,-8.76758861541748,-9.477062225341797,-9.606496810913086 -2055,2055,A132F,0.032811053,-1.449931937,-2.065231766,-2.556725852,-2.8732677439999996,-0.043875388,0.06911534400000001,-0.003493238,-0.025723338999999998,-1.530773819,-1.369090055,-1.8667900730000002,-2.263673459,-2.104999358,-3.0084523460000003,-2.703940525,-3.042594962,0.10320787,-0.95203174,-10.66905999,-11.04531861,-9.018539787,-10.73556838,-12.81246387,-9.733409279,-8.428305965,-8.117334739,-14.295979499816895,-18.34725570678711,-16.57344627380371,-17.209142684936523,-16.989791870117188 -2056,2056,A132I,0.009760616,-1.70974813,-2.475562956,-2.42746642,-2.806477679,0.01298041,-0.032247231,0.051768462,-0.085366657,-1.658560398,-1.7609358609999999,-2.295606648,-2.655519264,-2.232785938,-2.622146901,-2.655635845,-2.9573195130000003,-0.145854076,-1.065521983,-10.03374351,-10.26466418,-9.488431534,-9.169355644,-11.26150651,-9.984759659,-8.048737693,-6.609464196,-13.925930976867676,-17.276020050048828,-13.67078685760498,-15.395661354064941,-13.955509185791016 -2057,2057,A132H,0.116313931,-1.527950804,-2.021731608,-2.274665067,-2.352646332,0.111492013,0.117537473,0.115090388,-0.068841968,-1.26062039,-1.7952812180000002,-1.897666639,-2.145796576,-2.135875925,-2.413454209,-2.257695837,-2.447596826,3.835529539,1.616839589,-10.71533692,-11.01394444,-9.824030365,-10.2113696,-11.74507465,-10.78226556,-9.72973559,-10.89818902,-15.904256820678711,-18.22006607055664,-16.391809463500977,-18.01286506652832,-17.988128662109375 -2058,2058,A132K,0.040213241000000004,-1.671123709,-1.863874517,-2.744444229,-2.8224254930000003,0.11316524,0.06835418,0.012072301,-0.096010872,-1.7313075340000001,-1.6109398830000001,-2.067323788,-1.660425246,-2.606563069,-2.8823253889999996,-2.728382981,-2.916468005,-0.214287717,-1.069204396,-11.04650336,-11.04853158,-10.58577379,-10.45940125,-11.89576771,-11.24304246,-9.72973559,-10.89818902,-16.143253326416016,-21.567340850830078,-18.614307403564453,-19.226741790771484,-18.093578338623047 -2059,2059,A132M,0.09022340400000001,-1.296283006,-2.079955608,-2.293298444,-2.760355333,0.072039739,0.116418157,0.06402865,-0.077310373,-1.37011953,-1.222446481,-2.308195775,-1.8517154409999999,-1.76825381,-2.8183430780000003,-2.668224972,-2.852485694,0.378560797,-0.839550095,-11.13301672,-11.54976551,-10.7554671,-10.54537672,-12.78661772,-10.02785655,-9.248606446,-8.777925005,-13.30774974822998,-15.238743782043457,-13.042999267578125,-15.270751953125,-14.803245544433594 -2060,2060,A132L,0.037136439,-1.7554314819999999,-2.136470769,-2.222177353,-3.316870495,0.031193143,0.039675973999999996,0.034596904,-0.11489805800000001,-1.547910574,-1.96295239,-2.114375749,-2.158565789,-2.09731253,-2.347042175,-3.1733749510000004,-3.460366038,0.359371583,-0.956849455,-9.922089066,-10.14306073,-8.818730827000001,-9.282764191,-11.86145026,-9.504439316000001,-7.883132477999999,-5.875809567999999,-13.952737808227539,-17.18832778930664,-14.939817428588867,-16.373472213745117,-15.902482986450195 -2061,2061,A132N,-0.035823613,-1.5423479,-2.124174334,-2.615668421,-2.693649685,0.011981297,-0.042590637,-0.029056589,-0.025303934,-1.629508601,-1.455187199,-1.965524855,-2.2828238130000003,-2.203734141,-3.0276027,-2.6265840480000002,-2.760715321,-0.288281379,-1.029582573,-11.12883051,-11.12199509,-10.98154572,-10.46085942,-11.81339555,-11.26635675,-9.72973559,-10.89818902,-14.172173500061035,-15.871856689453125,-15.145040512084961,-16.044092178344727,-15.22537899017334 -2062,2062,A132Q,0.223275258,-1.464977241,-1.4447436830000002,-1.848192141,-2.31524903,-0.007387058,0.23699208800000002,0.209558427,-0.024547981,-1.445144816,-1.4848096659999999,-1.480131074,-1.4093562919999998,-2.195461615,-1.500922666,-2.317281527,-2.3132165330000003,3.6600276380000003,1.539543387,-10.88706402,-10.73500231,-10.37638845,-10.32904043,-11.78034626,-11.21454266,-9.72973559,-10.89818902,-15.622047424316406,-17.571613311767578,-15.62009048461914,-17.97415542602539,-17.098539352416992 -2063,2063,A132P,0.054740122999999995,-1.359358557,-1.978764977,-2.232701428,-2.31679992,0.06392502,0.040229705,0.069250541,-0.09458081900000001,-1.304114373,-1.414602741,-2.127471047,-1.830058907,-2.131597127,-2.3338057290000003,-2.332598285,-2.301001555,0.63560276,-0.7651545679999999,-9.453728931,-8.831089066,-9.837172417,-9.266142143,-9.79164328,-9.542597748,-8.347959236,-7.434468637,-12.158110618591309,-14.931465148925781,-12.689996719360352,-12.665687561035156,-12.007084846496582 -2064,2064,A132S,0.048387742000000004,0.031828906000000004,0.014568271,-0.006924016999999999,-1.153553251,0.000141085,0.062201562,0.034573921,-0.003773878,0.032633962999999995,0.031023849,0.009955158,0.019181384,0.01038225,-0.024230283999999998,-0.8304004340000001,-1.4767060669999998,0.57354371,1.350739897,-5.656036942999999,-5.2172524639999995,-5.80262352,-5.26595855,-6.557216553,-5.437133629,-6.0351906689999995,-4.007072365,-9.063227653503418,-8.687196731567383,-8.836164474487305,-9.305317878723145,-9.58123779296875 -2065,2065,A132R,-0.031128682,-1.678372908,-2.015521486,-2.8732124530000003,-3.12458746,0.066831497,-0.034769594,-0.02748777,-0.070073994,-1.715699951,-1.641045865,-1.817632999,-2.213409973,-2.612144786,-3.13428012,-2.9558134469999997,-3.293361473,-0.020652138,-1.05255572,-10.77764605,-10.59519766,-10.41551293,-10.39286393,-11.30013215,-11.184523599999999,-9.478356107,-9.568577795,-17.183198928833008,-20.516674041748047,-17.42612075805664,-18.844179153442383,-18.066877365112305 -2066,2066,A132T,-0.005427035,-0.006983294,-1.215919415,-1.6845347569999998,-2.174470391,0.019224322,0.017731886000000002,-0.028585956000000003,-0.035831681000000004,0.11881377800000001,-0.132780365,-1.22438106,-1.20745777,-1.580689658,-1.788379855,-2.128478302,-2.220462479,3.805997275,2.457253178,-6.68337422,-6.465436812999999,-6.510020493,-6.187431564,-7.202506812999999,-7.051475418,-6.301641336,-4.139465701000001,-10.452543258666992,-11.68807601928711,-8.966264724731445,-10.841094970703125,-10.583759307861328 -2067,2067,A132W,0.012252581,-1.5792686669999998,-1.9582124280000002,-3.022770532,-2.862191169,0.042107535999999994,0.038675114,-0.014169952,-0.06003002599999999,-1.4759171580000001,-1.682620175,-1.7741448519999998,-2.142280003,-2.790505387,-3.2550356760000003,-2.435204045,-3.289178292,0.5315922820000001,-1.0815985909999999,-11.44642563,-11.57371535,-10.68510567,-11.15671055,-12.74865271,-11.06794385,-9.72973559,-10.89818902,-16.34298324584961,-20.184486389160156,-18.439868927001953,-19.266407012939453,-19.694021224975586 -2068,2068,A132V,0.014852203000000001,-0.934913715,-1.5530998280000001,-1.875184636,-1.95815801,0.036240483,0.024177119,0.005527287,0.01766514,-0.770534158,-1.099293272,-1.7641277309999999,-1.342071924,-1.964548455,-1.785820816,-2.086368367,-1.829947653,4.363113437,2.4701415780000002,-8.552688213,-8.871125443,-8.242530334,-7.75441626,-9.585092171,-8.310276855,-7.929021317999999,-6.605900367,-10.83813190460205,-12.960153579711914,-11.397388458251953,-12.244729042053223,-11.828580856323242 -2069,2069,A132Y,0.040473425,-1.508546489,-2.377388556,-2.780837013,-2.8588182769999997,-0.0055845619999999995,0.079588475,0.0013583739999999999,-0.014423556,-1.528482022,-1.488610955,-2.040589535,-2.7141875769999997,-2.579828816,-2.98184521,-2.7016487280000003,-3.0159878260000004,-0.21230520000000003,-0.983991156,-11.538252900000002,-11.63020685,-10.21801668,-11.43909747,-13.44771854,-10.95622496,-9.72973559,-10.89818902,-16.054126739501953,-19.03359603881836,-16.70517349243164,-17.898889541625977,-17.752090454101562 -2070,2070,A133C,-0.00774145,0.001291328,0.037568662,-0.003170465,-1.849881352,0.096780884,-0.007817289,-0.00766561,-0.01070332,-0.034425536,0.037008192,0.035726364,0.039410959,0.0536446,-0.05998553,-1.702430536,-1.997332167,0.578072086,1.308581815,-9.389295607000001,-10.07753066,-8.681223152000001,-9.953741989,-8.865463959,-9.368518272000001,-6.656134571,-1.6463722440000002,-9.578808784484863,-9.21322250366211,-9.565423965454102,-8.761768341064453,-9.463908195495605 -2071,2071,A133E,-0.052919691,-1.26141188,-2.156214639,-2.164244365,-2.123472185,0.09342379,-0.057826017,-0.048013364,-0.055258882999999995,-1.2846287859999999,-1.238194974,-2.0464603919999997,-2.265968886,-1.8602519990000002,-2.46823673,-2.2617385469999998,-1.985205822,0.710260734,-0.731128344,-10.38900965,-10.70936898,-9.677686873999999,-11.33146502,-10.56433263,-9.66219474,-7.004870955,-5.546053054,-11.572612762451172,-17.063961029052734,-12.923192977905273,-10.738654136657715,-13.106486320495605 -2072,2072,A133D,-0.060583051,-1.197046488,-1.793192469,-1.641223277,-1.5592061959999999,0.086565835,-0.049196497,-0.071969605,-0.029375917999999997,-1.125666853,-1.268426123,-1.66564971,-1.920735228,-1.490436701,-1.7920098530000002,-1.801746619,-1.316665773,4.555122368999999,2.718828357,-9.25564059,-11.70155454,-8.116262825,-9.58336055,-9.877907927999999,-6.999117104,-6.404737485,-4.729045598,-12.472627639770508,-18.65431785583496,-12.934418678283691,-11.197328567504883,-14.032698631286621 -2073,2073,A133G,-0.020973722,0.019722893999999998,0.009274628,0.022143252000000002,-0.05375177,0.01095523,-0.044556730999999995,0.002609288,-0.043059914000000005,-0.05470645,0.09415223699999999,-0.0008277060000000001,0.019376962,0.0039499059999999996,0.040336597,-0.068984932,-0.038518607,1.38979435,2.429750622,-2.114148592,-2.90629068,-0.978243462,-2.0354526980000003,-2.8361305619999997,-1.8146255569999998,-2.057832576,-1.22210873,-4.95361328125,-7.193228721618652,-5.01006555557251,-3.9680042266845703,-4.063549518585205 -2074,2074,A133F,-0.063003197,-0.16112385099999998,-1.566228016,-2.287242107,-2.774922353,0.081603475,-0.026656091,-0.099350303,-0.08720464900000001,-0.017872849,-0.304374853,-1.273272562,-1.85918347,-1.910972909,-2.663511305,-2.789580712,-2.7602639939999998,2.527726898,1.081890835,-13.2825995,-13.01485751,-12.30837585,-15.19420873,-15.20173439,-10.69382101,-7.084619459,-4.132919461,-12.715250968933105,-16.180944442749023,-14.295884132385254,-12.728111267089844,-14.490824699401855 -2075,2075,A133I,-0.177098339,-1.082032108,-1.902831071,-2.362405789,-2.810495412,0.016525928,-0.139012072,-0.215184605,-0.14774653599999998,-0.762590155,-1.40147406,-1.737029855,-2.068632286,-1.754941444,-2.9698701339999998,-2.554368001,-3.0666228230000003,4.03891515,2.154251558,-8.751213298,-7.486889832,-8.086217292999999,-9.537004341,-10.36031095,-8.285644073,-5.97459938,-4.9894596,-11.423592567443848,-14.884381294250488,-13.35317611694336,-11.902616500854492,-12.772056579589844 -2076,2076,A133H,-0.043598824,-0.828241888,-2.190497255,-2.572620994,-2.631634991,0.028374381,-0.04745368,-0.039743968,0.003959035,-0.705576717,-0.950907059,-2.166378328,-2.214616182,-1.8832599209999998,-3.2619820660000003,-2.205565224,-3.0577047580000003,0.644202402,-0.5080581270000001,-12.08671349,-12.97476728,-11.02879521,-12.91909661,-12.404250099999999,-11.10665824,-6.687620064,-5.057104272,-13.890560150146484,-20.11758041381836,-14.161402702331543,-13.849405288696289,-14.316017150878906 -2077,2077,A133K,-0.017349745,-1.32063772,-2.2426710180000002,-2.46368511,-2.2612597340000002,0.20475411899999998,0.072780021,-0.107479511,-0.058972827,-1.204733827,-1.4365416130000002,-2.010031127,-2.475310909,-2.249791466,-2.677578753,-2.3502480180000003,-2.17227145,0.5453004920000001,-0.7157640409999999,-13.19439943,-14.33375819,-11.14777094,-13.90210912,-13.46599479,-13.12236411,-9.504542946,-9.511394586,-14.924436569213867,-21.70187759399414,-16.13137435913086,-13.38377571105957,-14.113563537597656 -2078,2078,A133M,0.028706852,-1.079755671,-2.4009662869999997,-2.621980379,-2.570070001,0.040153741,0.014876974,0.04253673,-0.158257748,-1.03953191,-1.119979431,-2.203851153,-2.598081421,-2.443611492,-2.800349265,-2.544068044,-2.596071958,1.042139125,-0.567285919,-9.771020815,-10.40731659,-7.9707571260000005,-11.66663051,-11.33992259,-7.470477257000001,-5.961816046,-3.2886428060000004,-10.309062004089355,-11.968135833740234,-11.299599647521973,-10.094246864318848,-12.137155532836914 -2079,2079,A133L,-0.023771839,-1.438953689,-1.914494184,-2.408779607,-3.356869229,-0.001307246,-0.040304201,-0.007239476,-0.075257224,-1.53840066,-1.339506718,-1.885544545,-1.9434438219999999,-2.329424866,-2.488134347,-2.952760164,-3.7609782939999996,0.259806378,-0.936989631,-10.74899775,-9.383950073,-9.574002411,-12.77702496,-12.16264791,-9.847363396,-6.396691796,-4.166792226,-12.02633285522461,-14.783994674682617,-14.381032943725586,-11.663692474365234,-13.191788673400879 -2080,2080,A133N,-0.033292747000000004,-0.112756883,-1.638780383,-2.58337349,-2.531463113,0.07096126900000001,-0.053428335,-0.013157159,-0.064517781,-0.158221697,-0.067292068,-1.32254094,-1.955019825,-2.407399319,-2.75934766,-2.507855872,-2.555070353,1.070058006,0.116851439,-9.605253931,-12.00489783,-7.957694388999999,-10.49814243,-8.553965309,-9.011569695,-6.204463429,-2.829194632,-11.542664527893066,-16.303882598876953,-8.71108627319336,-11.4080810546875,-11.946131706237793 -2081,2081,A133Q,-0.023546229,-1.310598168,-2.390766448,-2.549311171,-2.948945787,0.057132710999999996,-0.002123469,-0.044968988,-0.146579722,-1.357595245,-1.263601091,-1.9198544969999998,-2.861678398,-2.034676099,-3.063946242,-2.737192643,-3.16069893,3.595524223,1.277128463,-10.702571800000001,-11.49320576,-9.437451096,-11.95676651,-11.02177103,-9.603664581,-6.449225778,-5.065392547,-12.807727813720703,-18.655885696411133,-13.01394271850586,-11.400043487548828,-14.188471794128418 -2082,2082,A133P,-0.040955646,0.012284614,-0.882498583,-1.925318455,-2.451581678,0.056875402,-0.04850295599999999,-0.033408335,-0.024980272999999997,-0.080533337,0.10510256400000001,-0.494208593,-1.270788572,-1.768420162,-2.082216748,-2.481155871,-2.422007485,1.840730024,0.87914301,-11.33930482,-12.11989972,-10.01776789,-11.81966429,-12.75390804,-9.985284164,-8.210376834,-6.551920834,-10.667585372924805,-14.5451078414917,-14.536687850952148,-13.087361335754395,-12.348392486572266 -2083,2083,A133S,-0.012720948999999999,-0.026892709,0.001395003,3.39e-05,-0.15775672400000001,0.010813072,-0.04888161,0.023439712999999997,-0.007852237,-0.09218310800000001,0.038397691,0.001109568,0.0016804379999999998,-0.036577086,0.03664495,-0.162017303,-0.153496145,1.349787602,2.118171785,-5.868307744,-7.650990752999999,-5.309726974,-4.762800125,-6.779021667,-4.838999199,-5.161482371,-1.7807722030000002,-7.486313819885254,-9.006059646606445,-7.181056499481201,-7.242864608764648,-8.468351364135742 -2084,2084,A133R,-0.057304827999999995,-1.494103276,-2.121975064,-2.5040167209999997,-3.1528066139999997,0.098175297,-0.052174997,-0.062434658,-0.05081940099999999,-1.587892976,-1.4003135759999998,-1.902367744,-2.341582383,-2.1816366240000002,-2.826396817,-2.905342467,-3.4002707610000003,0.07455738099999999,-0.9866549920000001,-12.96936906,-13.85266205,-12.13774004,-14.21762111,-12.97143096,-11.66739115,-8.598798594,-7.209853282999999,-15.475776672363281,-20.763530731201172,-16.378849029541016,-13.276144981384277,-13.141485214233398 -2085,2085,A133T,-0.052233510999999996,-0.029663601,-0.0336638,-0.051248148,-0.12496147199999999,0.24018693100000002,-0.077983089,-0.026483932999999998,-0.02073436,-0.087887381,0.02856018,-0.03839383,-0.02893377,-0.034589767,-0.067906528,-0.13252866300000002,-0.11739428,1.38511591,2.253642628,-5.790642127999999,-6.242858147000001,-4.903600319,-5.1318749310000005,-7.3317110670000005,-5.343166176,-4.099609931,-0.277679915,-7.8596930503845215,-9.862085342407227,-7.384804725646973,-8.38957405090332,-8.874754905700684 -2086,2086,A133W,-0.039195892,-1.686324619,-2.166296844,-2.750810299,-2.815941524,0.060651124,-0.048767156,-0.029624627999999997,-0.204396868,-1.812635425,-1.560013813,-1.8239872080000001,-2.508606479,-2.489716279,-3.011904318,-3.0672940860000004,-2.5645889619999997,0.20075211899999998,-1.143334729,-14.05845078,-14.317036300000002,-12.42222981,-15.703980300000001,-15.26654169,-12.58246579,-8.158189584,-6.551920561,-14.403728485107422,-18.976980209350586,-16.898101806640625,-14.439602851867676,-15.738103866577148 -2087,2087,A133V,-0.06317093,9.08e-05,-0.718635949,-1.8157551980000002,-2.07968605,0.035907141000000004,-0.069466787,-0.056875072,-0.021419075,-0.038935517999999995,0.039117116,-0.362355132,-1.074916765,-1.51162056,-2.119889836,-2.059235143,-2.100136956,3.163755076,2.107755516,-6.042386852999999,-4.1772857210000005,-6.507542961,-6.505611946,-7.407618522999999,-5.613875114,-4.373040704,-3.5271899060000003,-9.0454740524292,-11.11500358581543,-10.87629222869873,-9.972900390625,-10.603238105773926 -2088,2088,A133Y,-0.02818377,-1.072351789,-1.965880954,-2.451031934,-3.001181548,0.023059045,-0.015989003999999998,-0.040378536,-0.066344536,-1.134889053,-1.009814525,-2.032940406,-1.898821501,-2.448792004,-2.4532718630000003,-2.8502785530000003,-3.152084542,0.359396107,-0.6622715020000001,-14.905617600000001,-14.50277558,-14.69903336,-16.30012209,-15.38673055,-13.63942642,-7.312161304,-5.653100571,-13.804530143737793,-18.60987091064453,-13.705318450927734,-13.72945785522461,-16.082345962524414 -2089,2089,N134A,-0.031905678,-0.052893833,-0.050714032,-2.100340961,-2.730906615,0.036228598,-0.011659487,-0.052151868,-0.008751383,-0.012415235,-0.09337243,-0.022693356,-0.078734707,-1.835683301,-2.36499862,-2.747694683,-2.714118547,0.709957921,0.676320108,-11.05552694,-10.63572585,-12.29716949,-10.86220663,-11.15836023,-10.32417251,-7.045983366000001,-5.832300094,-12.30775260925293,-13.64352798461914,-13.686564445495605,-12.648515701293945,-14.689865112304688 -2090,2090,N134C,-0.01571925,-0.045847610999999996,-0.013444764,-1.331412761,-3.421395372,0.057415135,-0.039915606,0.008477106,-0.029403756,-0.032370357999999995,-0.059324863,-0.05451088,0.027621352000000002,-1.274212471,-1.38861305,-3.204973289,-3.637817454,0.8239929159999999,0.7354547440000001,-12.30950106,-11.46564835,-12.57027802,-12.25768144,-13.5550625,-11.69883501,-8.083416532000001,-6.714562242,-14.633833885192871,-16.019033432006836,-14.362716674804688,-14.47690200805664,-13.466521263122559 -2091,2091,N134E,-0.078295274,-0.053043466,-1.6542827409999998,-2.913611882,-2.9469093539999998,0.082622979,-0.044107680999999996,-0.112482866,0.00820283,0.041841473,-0.147928405,-1.459545705,-1.849019776,-2.230562745,-3.5966610180000003,-2.4561932509999997,-3.437625456,0.94902859,0.070063754,-10.9101593,-10.27388471,-11.96832476,-9.868750977000001,-11.75392719,-10.68590885,-6.393825785,-4.749996065,-14.3519287109375,-16.758779525756836,-14.35568904876709,-14.728819847106934,-15.683136940002441 -2092,2092,N134D,-0.035669378,-0.051015135,-0.00905534,-0.255137305,-2.099289227,0.07213668200000001,0.0013324189999999998,-0.072671174,-0.086119805,-0.01091849,-0.09111178,-0.023083952999999997,0.004973273,-0.033893987,-0.47638062299999995,-1.8311545280000001,-2.367423925,0.786216963,1.308667843,-7.0461121460000005,-6.377023834,-6.372872887000001,-6.443305305,-7.84788195,-8.189476753,-4.720078186,-0.914599567,-11.649398803710938,-11.851362228393555,-11.967695236206055,-11.836030006408691,-14.64259147644043 -2093,2093,N134G,-0.042696060999999993,-0.009795514,-0.145007691,-2.095297776,-2.9425130580000003,0.06241614,-0.017741328,-0.067650793,-0.008849751,0.025510584,-0.04510161099999999,-0.06278225700000001,-0.22723312399999998,-1.920514221,-2.270081331,-2.790067165,-3.09495895,0.7416964079999999,0.667412464,-10.42146123,-9.592662025,-10.91589333,-10.94190007,-10.73856033,-9.918290398,-7.007411547,-5.203899748,-12.705850601196289,-13.30567455291748,-10.680344581604004,-12.38425350189209,-15.360676765441895 -2094,2094,N134F,0.010498702,0.007487915,-0.344239229,-2.15392903,-3.1872265019999997,0.007743906,0.032978118,-0.011980713999999998,0.0061070000000000004,-0.010664201000000002,0.025640031,-0.234071887,-0.45440657100000004,-1.886780769,-2.42107729,-2.811381279,-3.563071724,1.213764948,0.701710031,-12.88434884,-11.06513589,-13.25898917,-11.94002518,-14.99677922,-13.16081474,-7.547883882000001,-5.87411083,-17.42270278930664,-18.183238983154297,-18.17132568359375,-15.06774616241455,-17.478717803955078 -2095,2095,N134I,-0.046673060999999995,-0.009829494,-0.131542506,-2.3955424080000003,-2.8301996010000003,0.065328108,-0.01040813,-0.082937991,-0.019010722,-0.001396515,-0.018262473,-0.068053453,-0.195031559,-1.6731731490000001,-3.1179116660000004,-2.099463105,-3.5609360960000003,0.748306136,0.6931519559999999,-10.08582968,-8.239144936,-11.11518974,-9.893124352000001,-12.426028500000001,-8.755660857999999,-6.544382465,-4.675488579,-16.968185424804688,-17.93545913696289,-17.674856185913086,-14.255088806152344,-17.13994598388672 -2096,2096,N134H,-0.029996631,-0.004613213,-2.95e-05,-1.9124516480000002,-2.534620405,0.042258175,-0.007796745999999999,-0.052196516,0.013857851000000001,0.016669241,-0.025895666,-0.004333887,0.004274863,-1.8219820230000001,-2.002921273,-2.131933414,-2.9373073960000005,0.668888598,0.6755676290000001,-11.07472223,-10.3318203,-11.68149506,-11.27882735,-12.45844143,-9.623027,-7.147283712999999,-5.096033422,-9.863285064697266,-12.840887069702148,-10.80869197845459,-11.250295639038086,-14.013225555419922 -2097,2097,N134K,-0.033739776,0.01467132,-0.013498547,-2.214526153,-3.1263046,0.142865251,-0.010837392,-0.056642159000000004,0.015363206,0.00437672,0.024965919,-0.06228949599999999,0.035292402,-1.659630575,-2.76942173,-2.739133045,-3.513476155,0.812285027,0.698007114,-10.26030675,-9.642944069,-9.558576262999999,-10.47564099,-11.91747797,-9.706894447,-7.041619507,-5.491060002999999,-13.50654411315918,-16.0646915435791,-15.034482955932617,-12.607077598571777,-15.121451377868652 -2098,2098,N134M,-0.049266104000000005,-0.05664246,-0.130332789,-2.387290182,-2.975159889,0.051295742000000005,-0.021970349,-0.076561858,0.022073332999999997,-0.064668529,-0.04861639,-0.079771788,-0.18089379,-2.089349574,-2.685230789,-2.344943303,-3.605376474,0.689315232,0.64309882,-12.33233237,-10.55327546,-12.39575195,-12.6530474,-14.26567594,-11.79391107,-7.948603565,-6.7145622110000005,-16.19945526123047,-18.051265716552734,-17.113300323486328,-15.353189468383789,-18.59469985961914 -2099,2099,N134L,-0.029542872,-0.018657668999999998,-1.534011065,-2.022538301,-2.8785001130000003,0.055225166,0.00324346,-0.062329204000000006,-0.043735357999999995,0.002171321,-0.039486658,-1.49123858,-1.576783549,-2.096480629,-1.948595972,-3.146019875,-2.610980351,0.23709827,0.01807044,-10.79479305,-9.172898636000001,-10.38800302,-11.51635293,-13.29052838,-9.606182297,-6.015359236,-3.270115207,-14.90352725982666,-18.09833335876465,-17.65672492980957,-13.958909034729004,-17.331905364990234 -2100,2100,N134Q,-0.062254286,-0.022490201,-0.007066445,-1.6925473619999998,-3.0558708039999996,0.10440362,-0.046463643,-0.078044929,0.002472715,0.033018868,-0.07799926900000001,0.023879714,-0.038012603,-1.494933685,-1.890161039,-2.477526142,-3.634215465,0.644768291,0.702607311,-11.72171691,-11.41799112,-11.49758872,-11.50646503,-12.92059914,-11.26594056,-7.202670834,-5.874110754,-12.75684928894043,-16.30404281616211,-13.957904815673828,-12.744728088378906,-16.061248779296875 -2101,2101,N134P,-0.044540223,-1.523915926,-1.9510901459999999,-2.612290159,-3.4871754999999998,0.042372859000000006,-0.040107091,-0.048973354000000004,-0.045100920999999995,-1.512840084,-1.534991767,-1.757867527,-2.144312764,-2.019007189,-3.205573129,-2.9278134319999998,-4.046537568,3.505642387,1.211322266,-14.45038301,-13.34624961,-15.19516088,-14.25503292,-15.90435201,-13.55111964,-9.637723922000001,-10.19675467,-17.480239868164062,-20.113706588745117,-17.727561950683594,-18.02699851989746,-19.803699493408203 -2102,2102,N134S,-0.047201715,-0.016152634,-0.036010367,-1.87868483,-2.914040585,0.085059596,-0.021479542,-0.07292388799999999,-0.012722913,-0.015672712,-0.016632555,-0.06541710099999999,-0.006603632,-1.489961703,-2.267407956,-2.233042202,-3.595038967,0.901122658,0.7197793640000001,-10.732342,-9.959911346,-11.69039423,-11.01382729,-11.86434983,-9.13322728,-8.730166328,-7.771299106,-11.214849472045898,-12.133468627929688,-10.965375900268555,-11.619441986083984,-13.512200355529785 -2103,2103,N134R,-0.048921831,0.0030946640000000004,-0.01086617,-2.122802422,-3.074171492,0.09023775099999999,-0.039365822,-0.058477839000000004,-0.010479411999999999,0.030346911,-0.024157584,-0.023213246,0.001480907,-1.950470648,-2.295134195,-2.45594185,-3.692401134,0.56372064,0.6612275639999999,-12.85331412,-11.57918983,-14.37192673,-13.03938541,-13.69802308,-11.57804555,-6.98778989,-5.326581798,-14.513925552368164,-16.18769073486328,-14.801021575927734,-13.20612907409668,-18.19976806640625 -2104,2104,N134T,-0.022748057000000002,-0.006699095,-0.009502881,-1.2409259990000001,-2.597705253,0.054396413,-0.011207449,-0.034288665,-0.028674185,0.007908243,-0.021306433,-0.027024659,0.008018896999999999,-1.003159122,-1.478692875,-2.222540679,-2.972869827,2.050725303,1.39093148,-8.73578004,-7.600750511,-9.12375045,-8.796739319,-10.2345674,-7.923092522,-7.088532999,-6.312017684,-13.047481536865234,-13.542474746704102,-12.572914123535156,-13.677898406982422,-13.459433555603027 -2105,2105,N134W,-0.044790109,-0.013371137,-1.453378166,-2.3085607280000002,-3.258416571,0.047954748,-0.022183973,-0.06739624400000001,0.004268285,-0.016559696000000002,-0.010182578000000001,-1.3896638430000001,-1.5170924890000002,-2.105715391,-2.511406064,-2.749489291,-3.767343851,2.358808048,0.8550511390000001,-14.8527196,-13.25204587,-15.27805738,-14.63193145,-16.7749931,-14.32657022,-9.637723922000001,-10.19675466,-16.242610931396484,-19.160085678100586,-18.779441833496094,-17.56399154663086,-21.419593811035156 -2106,2106,N134V,-0.014140305,0.015117081000000001,-0.009214773,-1.76977729,-2.740153276,0.065345853,-0.002966844,-0.025313766,-0.004280686,0.023714027999999998,0.006520134,-0.012592373,-0.005837173,-1.6576609830000002,-1.881893597,-2.984318067,-2.495988485,0.64031039,0.688608157,-10.48935466,-8.875279915,-12.12948248,-10.45970982,-11.90717769,-9.07512339,-6.721214749,-5.540741262,-15.141080856323242,-17.688398361206055,-15.950705528259277,-13.190089225769043,-17.920272827148438 -2107,2107,N134Y,-0.036495177999999996,-0.015402827,-0.10655888300000001,-1.9590956080000002,-2.998510307,0.043191537,-0.018225627,-0.054764729000000005,0.009372842,0.021653277999999998,-0.052458932,0.029380627000000003,-0.24249839199999998,-1.8319939619999999,-2.086197253,-2.388617686,-3.6084029280000003,0.565377374,0.674038577,-13.30681882,-12.53292814,-13.82758156,-12.06288181,-14.61598795,-13.49471465,-7.640701506,-4.912788031,-13.352203369140625,-15.980548858642578,-16.00337028503418,-14.346993446350098,-15.954828262329102 -2108,2108,L135A,-0.02112953,0.010085161,0.005087024,0.024460949,-1.73120652,0.032501255,-0.009176700999999999,-0.033082358,-0.04772345,-0.011639958999999998,0.031810281,0.010965899999999999,-0.000791853,0.043982252,0.004939646,-1.5871025069999998,-1.8753105330000002,0.7485259120000001,1.3197165309999999,-7.2134899279999996,-7.591431007000001,-9.282946922,-5.359962395,-7.711955337999999,-6.121153976,-5.936601506000001,-1.7549465219999998,-8.092655181884766,-11.712611198425293,-9.72696304321289,-10.51677131652832,-11.356766700744629 -2109,2109,L135C,-0.068192055,-0.049227127,-0.023001083999999998,-0.245550479,-1.94117432,0.100961328,-0.075620361,-0.060763749000000006,0.035757594,-0.070038136,-0.028416117999999997,-0.03842676,-0.0075754080000000005,-0.079049642,-0.412051316,-1.742133104,-2.140215535,0.972925785,1.323018354,-10.31277899,-10.60326263,-11.30852621,-9.685007828,-9.835293816,-10.13180445,-8.313445902,-6.262391854,-10.717781066894531,-12.04944896697998,-11.094077110290527,-12.655110359191895,-12.916653633117676 -2110,2110,L135E,0.007769139,0.029143981,0.009569026999999999,-0.17222915100000002,-1.681275963,0.015336599,0.001090997,0.014447281000000001,-0.091666698,0.030596815,0.027691146,0.036932626,-0.017794573,0.059269577999999996,-0.403727879,-1.696077904,-1.666474021,0.49601981700000003,1.304143634,-9.48113891,-7.940165825,-11.96383719,-7.78771685,-9.823459297000001,-9.890515387999999,-6.647918695,-4.268362122,-11.140268325805664,-14.861270904541016,-10.964254379272461,-13.703171730041504,-11.563939094543457 -2111,2111,L135D,-0.060098902,-0.8729846440000001,-1.800587346,-2.288358611,-2.91674579,0.004086522,-0.074740738,-0.045457066,0.002506684,-0.820424178,-0.9255451090000001,-1.6953224480000002,-1.9058522430000002,-2.166151115,-2.4105661069999997,-2.732851302,-3.1006402769999997,3.013880227,1.092637207,-13.705596100000001,-12.7784179,-16.37372536,-12.18777766,-14.11613171,-13.07192788,-9.984269775,-9.572265932,-12.743453979492188,-15.970464706420898,-12.652645111083984,-15.792494773864746,-16.124555587768555 -2112,2112,L135G,0.013196296000000001,0.01755985,-0.8237607140000001,-1.738984132,-2.374463158,0.06270600900000001,0.039844467,-0.013451876000000001,-0.031677281,-0.020063442,0.055183142000000004,-0.617837862,-1.0296835659999999,-1.503191226,-1.974777038,-2.61982839,-2.129097925,2.0856737659999998,1.0868447909999999,-11.02349439,-10.895482800000002,-13.19403145,-8.855890938,-11.35084586,-10.82122091,-7.226935132,-4.897045662,-12.129047393798828,-14.217467308044434,-12.58427619934082,-14.615601539611816,-14.195554733276367 -2113,2113,L135F,-0.014543203000000001,0.011614278,0.012121934,-0.008153599000000001,-1.195243408,0.037900525,0.011665463999999999,-0.04075187,0.068940289,-0.032231694,0.055460249,-0.014307465,0.038551333,0.026693945,-0.043001142,-1.417740095,-0.97274672,0.675350322,1.3239672009999999,-4.925340907,-4.813751976,-4.920964729,-5.7272669910000005,-4.676099884,-4.488620956,-4.947799439,-3.626605222,-8.977761268615723,-9.830394744873047,-8.881447792053223,-9.309194564819336,-11.204658508300781 -2114,2114,L135I,0.082884663,0.01490221,0.041074387999999996,0.024461122999999998,0.015083205,-0.031827975,0.11898029199999999,0.04678903400000001,0.034212518,-0.029245282,0.059049702,-0.00661439,0.088763165,-0.00057061,0.049492855,-0.04751424,0.077680649,1.493007229,2.630361326,-4.182949367,-5.975792732,-4.25051638,-3.047071709,-4.657408043,-2.98395797,-4.356210632,-0.9945509140000001,-7.276900768280029,-8.920698165893555,-6.469076156616211,-7.313111305236816,-7.839948654174805 -2115,2115,L135H,-0.053313506,-0.024937072999999997,-0.012673908999999999,-1.172863508,-1.802150135,0.037858204,-0.042277499999999996,-0.064349511,-0.026613831,-0.039582591,-0.010291554,-0.010762826999999999,-0.014584991,-0.9943386540000001,-1.3513883619999998,-2.0590940019999997,-1.545206267,2.188042586,1.507923098,-10.24109932,-9.810795784,-11.23078505,-9.030299918999999,-8.921526611,-12.21208923,-7.03763026,-5.148851805,-9.813844680786133,-10.940370559692383,-8.898820877075195,-10.617454528808594,-10.73977279663086 -2116,2116,L135K,-0.012480836,0.003177875,-0.030873737999999998,-0.42797057899999996,-1.541480467,0.052686377,0.028258301,-0.053219973,-0.017927976,-0.009625544,0.015981293,-0.007172176,-0.054575299,-0.126402661,-0.7295384970000001,-1.6230536709999999,-1.459907262,1.074426554,1.3447120769999998,-7.985608768,-9.036825653,-10.20333436,-5.804211922,-7.568170265,-7.31550164,-5.156806906,-2.566029227,-8.151054382324219,-9.379585266113281,-8.163232803344727,-7.3533854484558105,-7.164792537689209 -2117,2117,L135M,-0.032458600000000004,-0.025005153,0.032575086,-0.006326065,-0.163311658,0.020427028,-0.030792832000000003,-0.034124367,0.004974043,0.024990601,-0.07500090599999999,0.064383968,0.0007662039999999999,0.011470156,-0.024122285,-0.160308867,-0.166314449,1.41972547,2.254221664,-5.157165701,-5.349719574,-6.529141815,-4.862355331,-5.655430312999999,-3.3891814730000003,-5.437422234,-1.3981329040000001,-6.136288642883301,-9.183672904968262,-6.241260528564453,-7.475219249725342,-8.305952072143555 -2118,2118,L135N,0.006785134,-0.009171788,0.001135201,-1.473667881,-2.400954055,0.043084177,0.020420873,-0.006850605,-0.00965376,-0.028013031,0.009669455,0.011812268999999999,-0.009541866999999999,-1.303158894,-1.6441768680000002,-2.3817424419999997,-2.420165667,0.55444544,0.709231611,-11.25833726,-11.30514161,-12.13519597,-10.36597773,-11.39248516,-11.09288583,-8.109246784,-6.111214092999999,-10.55486011505127,-12.178316116333008,-10.318318367004395,-12.833127975463867,-12.85315227508545 -2119,2119,L135Q,-0.001100287,0.036382714,0.034291793,0.025451976,-1.193573049,0.04227883599999999,0.033919461,-0.036120035,0.048353815,0.040733639,0.032031789,0.054439743,0.014143842,0.055366995,-0.004463044,-1.15516019,-1.231985908,0.688308438,1.340989175,-8.331376596,-5.718701987999999,-11.8915761,-6.718123756000001,-7.140618233,-10.1878629,-6.146894545,-3.4665153810000002,-8.35012149810791,-10.897527694702148,-8.49382495880127,-10.258366584777832,-8.804624557495117 -2120,2120,L135P,-0.019019823,-1.496527164,-2.0523706230000003,-2.363919347,-2.8530553519999997,0.025867572000000002,-0.009614815,-0.02842483,-0.048074806,-1.466004289,-1.5270500390000001,-1.9643718019999998,-2.140369443,-2.29438497,-2.433453723,-2.594817267,-3.1112934360000004,0.009614745,-0.9341182259999999,-12.67727379,-12.57299569,-14.63686118,-11.46850156,-12.5871069,-12.12090364,-9.984269775,-9.572265932,-13.52253246307373,-14.98123550415039,-13.834005355834961,-15.672460556030273,-15.38724136352539 -2121,2121,L135S,-0.003435025,-0.0012869469999999999,0.020849316,-0.901277792,-1.8798725930000002,0.016619586000000002,0.041274773,-0.048144822000000004,-0.047999663,-0.015466681000000001,0.012892787,-0.002499217,0.044197849000000004,-0.677903818,-1.124651765,-2.089702045,-1.67004314,1.8485131590000001,1.391908521,-8.43832287,-9.450732719,-9.785154381,-7.220001167,-8.067446167,-7.668279915,-6.166430375,-4.659426326,-10.092251777648926,-12.65140151977539,-10.770096778869629,-12.439674377441406,-12.68810749053955 -2122,2122,L135R,-0.030322266,-0.019481681,0.007083736,-1.212068172,-1.8918507180000002,0.044034616,-0.026117932000000003,-0.034526599,-0.057566589,-0.010008396999999999,-0.028954964,0.006254381999999999,0.007913089,-0.841499551,-1.582636792,-2.133021546,-1.650679889,1.848576741,1.352505485,-9.231775661,-7.6033299329999995,-10.93156673,-7.558507744,-8.277736572,-11.78773733,-5.935458678,-3.570514906,-9.482972145080566,-9.262918472290039,-8.1840238571167,-10.58879566192627,-9.037641525268555 -2123,2123,L135T,-0.061223034,-0.009615766999999999,-0.015524672,0.002768015,-1.77295641,0.025871492000000003,-0.071176323,-0.051269745,0.032833041,-0.007684469,-0.011547065,0.011375178,-0.04242452099999999,0.003879482,0.0016565470000000002,-1.482085631,-2.063827189,0.64119709,1.3186931709999998,-8.406645378,-9.007511322000001,-9.84318692,-6.777353172000001,-8.376973969,-8.028201507999999,-6.563926052,-3.884525252,-8.748079299926758,-11.787275314331055,-9.115910530090332,-10.81307601928711,-10.705827713012695 -2124,2124,L135W,-0.023233632,-0.01870029,-0.7126437809999999,-1.724436773,-2.6627183309999998,0.026094698,0.0043791279999999995,-0.050846392000000004,-0.028569748,-0.038741488,0.001340909,-0.44776979200000006,-0.97751777,-1.64030605,-1.808567496,-2.632974969,-2.6924616919999997,1.716388821,0.862657053,-9.355307057000001,-9.383733772000001,-9.918236801,-9.177507729,-7.676531036,-10.62052595,-7.063058527999999,-2.745522269,-10.37484359741211,-13.37419605255127,-10.197391510009766,-12.91524887084961,-13.772130966186523 -2125,2125,L135V,0.035417055,-0.005919798,0.033200827999999995,0.031691952999999995,-0.036550333,0.0038500979999999997,0.024684172,0.046149937,-0.015398708999999998,-0.014764977,0.0029253820000000002,0.024532592000000002,0.041869063,-0.0033825009999999996,0.066766407,-0.047415845,-0.02568482,1.415812981,2.6020213130000003,-4.624903035,-5.070366783,-5.662694664,-3.246710335,-5.019648628000001,-4.125094765,-3.904763051,-1.3900099719999999,-7.360103607177734,-9.501200675964355,-7.180263519287109,-8.100566864013672,-9.478667259216309 -2126,2126,L135Y,0.012562361999999999,-0.000852569,0.003671587,-1.28702811,-2.43111952,0.050933294000000004,0.041564558,-0.016439834,-0.008733995,-0.070080839,0.068375701,-0.020146228999999998,0.027489403,-1.308678598,-1.2653776209999998,-3.031725985,-1.830513055,0.801065692,0.7287268490000001,-7.7630292270000005,-8.572352875,-7.999037819,-7.599189705,-6.751853972999999,-7.892711761,-5.809777577,-4.034836862,-8.827448844909668,-11.310111999511719,-8.99645709991455,-10.724824905395508,-12.210860252380371 -2127,2127,L136A,-0.047977402,0.00928127,-0.017677571,-0.12551959099999999,-1.717249236,0.012444281000000001,-0.040676587,-0.055278216,0.044319726,0.0033588209999999997,0.015203719,-0.001931135,-0.033424006,0.012688931,-0.263728112,-1.946422787,-1.488075684,0.680394701,1.298568349,-7.1318434879999995,-5.85375518,-7.1536006620000006,-6.327904861,-7.820993301000001,-8.502963432,-5.382692475,-4.1737922,-8.679298400878906,-12.023441314697266,-10.25202751159668,-10.216239929199219,-13.371097564697266 -2128,2128,L136C,-0.11305580800000001,-0.03131713,-0.099447597,-1.307198378,-2.7536823939999997,0.011941016,-0.129508249,-0.096603366,-0.001686899,0.036046841,-0.09868110000000001,-0.012428628,-0.18646656600000003,-1.150514658,-1.463882097,-2.2132697709999998,-3.2940950160000004,0.833857317,0.7549000570000001,-8.707652716,-8.367589942999999,-8.680756942999999,-8.572706841,-9.934712555,-7.982497298999999,-7.05935192,-4.103830045,-10.962985038757324,-13.328377723693848,-11.826780319213867,-11.909662246704102,-14.287778854370117 -2129,2129,L136E,-0.035618852,-0.789348506,-2.084277019,-2.396207913,-3.025057795,-0.025552081,-0.011584163,-0.05965354,0.045593757,-0.33739655700000004,-1.241300455,-1.648276351,-2.520277686,-2.713322505,-2.0790933209999998,-2.787073003,-3.263042586,1.3275182559999998,0.069593618,-12.03008268,-10.76053468,-12.20629511,-11.63861162,-13.28215435,-12.26281763,-9.762993266,-10.45371609,-14.594592094421387,-16.62723159790039,-14.049566268920898,-14.488566398620605,-16.155487060546875 -2130,2130,L136D,-0.072914699,-1.455973755,-2.338652659,-2.7130529219999997,-2.768838785,0.074176139,-0.040743257000000005,-0.105086141,0.065907432,-1.5011133140000001,-1.410834195,-2.061280106,-2.616025212,-2.28122822,-3.144877624,-2.6560087130000003,-2.8816688569999998,-0.271717848,-0.947047291,-12.85720479,-12.21537987,-13.03692766,-12.255578,-14.09393658,-12.68420184,-9.762993266,-10.45371609,-16.992748260498047,-18.052574157714844,-15.478593826293945,-15.820438385009766,-17.87238311767578 -2131,2131,L136G,-0.061058491,-0.022520349,-1.157233897,-2.076595831,-3.003875111,0.021011738,-0.04671705599999999,-0.07539992599999999,0.036435712,-0.004109567,-0.04093113,-1.092033257,-1.222434536,-1.804522985,-2.348668677,-2.621260316,-3.3864899060000004,2.459935651,1.127724855,-11.680655499999999,-11.111664999999999,-11.45060035,-11.25702106,-12.47563342,-12.10835767,-9.043111977999999,-7.87811875,-12.792275428771973,-17.212757110595703,-15.030984878540039,-14.796720504760742,-17.077787399291992 -2132,2132,L136F,-0.057483584000000004,-0.7031582040000001,-1.7242718369999999,-2.681837811,-2.825669304,0.019302395,-0.07564674,-0.039320428,0.099180835,-0.480647593,-0.925668814,-1.5952327419999999,-1.8533109319999999,-2.555543546,-2.808132076,-2.3282640480000003,-3.3230745589999997,1.6446582630000002,0.169514665,-9.440853313,-9.174938179,-8.878201736,-9.448491074,-10.09091125,-9.611724319,-7.488051102000001,-5.502519691,-8.912618637084961,-10.9781494140625,-10.158540725708008,-8.090201377868652,-11.15460205078125 -2133,2133,L136I,0.03500675,0.014234416000000001,-0.010748454,0.045077480999999996,-0.17496484899999998,-0.031483614,0.039529694,0.030483805,0.055072857,0.039567842,-0.01109901,-0.011062556000000001,-0.010434352,0.025922618999999997,0.064232342,-0.156499002,-0.193430695,1.220572632,2.066951262,-3.114348335,-2.10352832,-3.616627937,-3.2215591960000003,-3.8873522030000003,-2.742674019,-3.720659491,-1.92446127,-6.0643157958984375,-8.436100006103516,-6.522627830505371,-4.144015312194824,-8.090705871582031 -2134,2134,L136H,-0.133611849,-0.961515654,-2.187029892,-2.50685792,-2.539765038,0.055439369,-0.123544906,-0.143678791,0.066465026,-0.67081086,-1.252220447,-1.991030681,-2.383029102,-2.454016844,-2.559698995,-3.129827333,-1.949702742,1.490618306,-0.11357019800000001,-12.88937807,-11.65083229,-12.62560618,-13.14513167,-13.73309621,-13.29222398,-9.762993266,-10.45371609,-14.427927017211914,-14.987781524658203,-14.44564437866211,-13.945972442626953,-15.386506080627441 -2135,2135,L136K,0.032910394,-1.73043469,-2.014473315,-2.476919208,-2.532705071,0.047366728,0.10006138199999999,-0.034240594,0.093428506,-1.6991243930000002,-1.7617449859999998,-2.192344395,-1.836602235,-2.111262514,-2.8425759010000005,-2.185013011,-2.88039713,-0.697728144,-1.062722563,-12.07154769,-11.28681774,-12.5124899,-11.78379061,-12.48402549,-12.290614699999999,-9.762993266,-10.45371609,-14.722187995910645,-16.23964500427246,-17.503948211669922,-14.552194595336914,-17.01560401916504 -2136,2136,L136M,-0.029343821000000003,-0.009509011,-0.024946338999999998,-0.002533488,-1.15861749,0.035162413999999996,-0.041315545,-0.017372096,0.01236855,0.002067072,-0.021085093,-0.02502706,-0.024865618,0.009943671,-0.015010646,-0.686702458,-1.630532521,0.9190990640000001,1.4519582080000002,-3.941644365,-3.630144768,-3.65348008,-4.716066772,-3.926100258,-3.782429947,-5.103221506000001,-2.8213464339999996,-6.8392558097839355,-8.368721008300781,-8.070928573608398,-6.471366882324219,-8.649812698364258 -2137,2137,L136N,-0.001632136,-0.484794756,-1.588947401,-2.777542129,-3.07188862,0.025381346000000003,0.042447398,-0.045711669,0.015388638999999999,-0.30439926300000003,-0.6651902479999999,-1.503348853,-1.6745459480000002,-2.1755946390000003,-3.3794896189999997,-2.726466391,-3.417310848,1.457219834,0.158399669,-10.95537372,-10.46876717,-11.01204106,-10.99690937,-12.07986827,-10.21928275,-7.9652306710000005,-5.198272622,-15.060391426086426,-15.853728294372559,-14.410364151000977,-14.248457908630371,-16.120372772216797 -2138,2138,L136Q,-0.12448723,-0.552065837,-1.688036626,-2.562436889,-2.618222752,0.003310123,-0.046745075999999997,-0.202229383,0.140762384,-0.13627484,-0.9678568329999999,-1.464127449,-1.911945802,-2.286135555,-2.838738222,-2.359886052,-2.8765594510000003,0.935169327,0.06672568400000001,-10.16148378,-8.930022079,-10.65096381,-10.10465358,-9.999408379,-11.12237106,-7.938757164,-7.029747338,-12.875043869018555,-13.546844482421875,-13.160741806030273,-11.880270004272461,-13.912275314331055 -2139,2139,L136P,-0.061274714,-1.51525225,-2.131193669,-2.384797528,-3.068219645,0.023570315,-0.044339724000000004,-0.078209704,0.0055320280000000005,-1.462865425,-1.567639075,-2.033251382,-2.229135956,-2.077108237,-2.692486819,-3.0081912319999997,-3.128248057,3.250659202,0.881743811,-12.02477847,-11.32305422,-11.98575116,-11.44825673,-13.25956449,-12.10726572,-9.74733258,-10.38510711,-14.511751174926758,-13.482563972473145,-15.86329460144043,-12.974017143249512,-12.939383506774902 -2140,2140,L136S,-0.032698547,-0.0149125,-1.081950833,-1.981957552,-2.769350458,0.042260005,0.008831511,-0.074228604,0.083328179,-0.0063195809999999995,-0.023505419,-0.983593851,-1.180307814,-1.83343105,-2.130484053,-2.7396904610000004,-2.799010455,2.359781327,1.071347823,-9.628428735,-8.825515755,-9.487181686,-9.525306801000001,-10.63305678,-9.671082657000001,-7.669048796,-5.858593899,-12.613731384277344,-14.191606521606445,-13.194134712219238,-12.654376029968262,-14.676154136657715 -2141,2141,L136R,-0.088540725,-1.489062885,-2.334851848,-2.288505153,-3.417355034,0.018298926,-0.064954425,-0.112127024,-0.034450625,-1.548717559,-1.429408211,-2.079726122,-2.589977573,-1.89390889,-2.683101415,-2.937696165,-3.897013903,-0.19964626100000002,-0.997231489,-12.03356076,-11.51466544,-11.85562979,-11.75152725,-12.5081244,-12.5378569,-9.762993266,-10.45371609,-15.834545135498047,-15.589733123779297,-16.902196884155273,-14.497533798217773,-16.02560043334961 -2142,2142,L136T,-0.044930806,-0.018432716000000002,-0.034729245,-1.5119941069999998,-2.49032899,0.041582012,-0.028604808,-0.061256804000000005,0.042104697999999996,-0.000748092,-0.03611734,-0.030387585,-0.039070905,-1.268203419,-1.755784795,-2.228010564,-2.7526474160000003,0.8598033690000001,0.736126811,-8.839815788,-8.246984177,-9.612352806,-8.502282845,-8.686276031,-9.151183083,-6.572016099,-5.751164535,-9.93811321258545,-12.120462417602539,-10.328146934509277,-10.54602336883545,-13.309772491455078 -2143,2143,L136W,-0.09308815,-1.7527600559999998,-2.3483155890000003,-2.847654588,-2.7925160769999997,0.015483998999999998,-0.0678006,-0.118375699,-0.031369569,-1.709389256,-1.796130856,-2.237371365,-2.459259812,-2.105136961,-3.590172215,-2.434159964,-3.1508721889999998,-0.48230219799999996,-1.09202305,-11.63108162,-10.90380845,-11.068470199999998,-11.32970312,-12.80800862,-12.04541773,-9.017207663999999,-7.87811875,-12.095600128173828,-14.469510078430176,-14.64354133605957,-13.013484001159668,-15.069192886352539 -2144,2144,L136V,-0.035246587999999995,-0.009182113,-0.040336823,0.0027438429999999997,-0.906487138,0.040550342999999996,-0.035048036,-0.03544514,0.057409725999999994,0.011960223,-0.030324447999999997,-0.0010865480000000001,-0.079587097,0.03987811,-0.034390423999999996,-0.7252374979999999,-1.087736777,0.457052479,1.3538469290000001,-3.59190085,-2.259235275,-3.610065979,-3.217830475,-4.880787399,-3.9915851210000004,-3.398659315,-2.0624674919999997,-5.647835731506348,-8.14934253692627,-6.427370071411133,-6.148068904876709,-9.735282897949219 -2145,2145,L136Y,-0.030087677,-1.7519262580000001,-2.36257114,-2.776562026,-3.181832892,0.0258452,0.036554632999999996,-0.09672998599999999,0.009255314,-1.871550698,-1.6323018169999999,-2.665800696,-2.0593415840000002,-2.186778806,-3.3663452460000003,-2.9594993080000003,-3.404166475,-0.455607935,-1.093465696,-12.52745262,-11.67977261,-12.29079562,-12.65009378,-13.26518274,-12.75141833,-8.875480134,-7.87811875,-11.659423828125,-13.921878814697266,-13.357295036315918,-11.614397048950195,-15.198978424072266 -2146,2146,L137A,-0.059570186,-0.017688806,-0.029302322999999998,-0.017461453000000002,-1.775437387,0.043049642,-0.047382848,-0.071757523,0.330993219,0.000985053,-0.036362665,-0.020735485,-0.03786916,0.021220889,-0.056143795,-1.608129146,-1.9427456269999999,1.061440403,1.3460313019999999,-8.162671628,-8.174486465,-8.809668816,-7.404939079,-7.465432045,-8.958831734,-5.9828056929999995,-3.7942326669999997,-8.595808982849121,-12.72512435913086,-13.092510223388672,-11.03119945526123,-12.029698371887207 -2147,2147,L137C,-0.048967339000000006,-0.037603284,-0.047532978,-0.170590627,-1.808855586,0.081004982,0.008398913000000001,-0.10633359,0.23408320600000002,0.012358085,-0.08756465199999999,-0.037969254,-0.057096702,-0.046426989,-0.294754265,-2.088854525,-1.528856646,0.60703955,1.287184767,-10.97683732,-11.31605009,-10.47656591,-12.42564502,-9.920069519,-10.74585605,-8.342710653,-5.813794026,-10.349363327026367,-13.262151718139648,-13.996997833251953,-11.800975799560547,-11.639907836914062 -2148,2148,L137E,-0.058991602000000004,0.025528936000000002,-0.019226826000000002,-1.0239925859999999,-2.8850004460000003,0.05734637099999999,-0.032574723,-0.08540848,-0.021189298999999998,0.052137575,-0.001079703,0.005559413000000001,-0.044013064000000005,-0.513327443,-1.5346577280000002,-2.733067882,-3.03693301,1.089601281,0.981572305,-11.47701017,-11.59474796,-11.46526794,-11.93960304,-10.71418007,-11.67125184,-7.853488484,-5.553313135,-12.678272247314453,-15.699393272399902,-14.137941360473633,-15.101816177368164,-15.16723346710205 -2149,2149,L137D,-0.008079952,-0.34447346799999995,-1.507554579,-2.07133342,-3.145786752,0.065983242,0.011982738,-0.028142641,0.507084478,-0.094638326,-0.59430861,-1.45213329,-1.5629758669999998,-1.9204101519999999,-2.2222566880000003,-2.917759313,-3.37381419,2.5822294180000003,1.078781934,-13.71807731,-13.60663083,-14.00673497,-14.11059231,-12.67638992,-14.19003853,-10.171095,-9.715937357,-13.99337387084961,-18.856063842773438,-14.54934310913086,-16.366008758544922,-16.24700355529785 -2150,2150,L137G,-0.037342002,-0.004236591,-0.046279539,-1.0880812229999999,-2.270538407,0.057072169000000006,-0.021038887000000003,-0.053645116,0.054322569,-0.011380731000000002,0.002907549,-0.060599125,-0.031959952,-0.674595548,-1.5015668969999998,-2.195657834,-2.34541898,1.7215269919999998,1.329705029,-11.83380367,-12.44707608,-11.49548137,-11.30909789,-11.16332382,-12.75403921,-7.708159515,-4.862640782,-11.052685737609863,-15.272242546081543,-14.190768241882324,-14.799217224121094,-14.756990432739258 -2151,2151,L137F,0.018682968,0.010123453000000001,0.036700991,0.020510729,-0.950327725,0.129616703,0.05532672,-0.017960784,0.029963222999999997,-0.026176527,0.046423433,0.015138875,0.058263107,0.045627562999999996,-0.004606105,-0.761463254,-1.139192195,0.582916593,1.366205451,-6.908805071000001,-7.754445572000001,-5.817833855,-8.553684752999999,-6.113210518,-6.304850655,-4.240069419,-1.4197225169999999,-6.715845108032227,-9.192896842956543,-10.171319007873535,-6.384525775909424,-7.34332275390625 -2152,2152,L137I,0.005518566999999999,-0.049275277,-0.003329892,0.045246330999999994,-0.155949816,0.017372823,0.034788184,-0.02375105,0.17609125899999997,-0.028526187,-0.070024367,0.022054515,-0.028714298,0.032424087000000004,0.058068575,-0.123266251,-0.18863338,1.196778844,2.1816340380000003,-4.889278818999999,-4.7071694410000005,-4.784677605,-3.5409266660000003,-5.208375877,-6.205244507000001,-4.167821289,-0.501860826,-7.5885443687438965,-8.344816207885742,-7.262859344482422,-8.722155570983887,-6.903926849365234 -2153,2153,L137H,-0.025899914,-0.034918216,-0.06977432900000001,-1.561841382,-2.716401962,0.066766967,-0.010502491999999999,-0.041297336000000004,0.37841786899999996,-0.039828896,-0.030007536,-0.10014329300000001,-0.039405365,-1.3500773330000002,-1.77360543,-2.7184943560000003,-2.714309567,0.918048883,0.7398249290000001,-11.82039254,-11.00237223,-11.63715829,-13.79455672,-9.94888459,-12.71899088,-7.301555472,-5.489362878,-10.779107093811035,-12.987164497375488,-13.178922653198242,-13.03941535949707,-13.023035049438477 -2154,2154,L137K,-0.029615044,-0.09416432599999999,-1.819391843,-2.481318007,-3.0060790230000003,0.108637071,0.010184707,-0.069414795,-0.06694679,-0.17246611,-0.015862542,-1.600385019,-2.038398666,-1.88361578,-3.0790202339999997,-2.8229729939999997,-3.1891850510000004,2.769547998,1.13690377,-13.41062022,-13.40594216,-13.76779122,-13.82232706,-11.85139246,-14.20564821,-8.939746547,-6.714215116,-13.197164535522461,-16.11070442199707,-12.314007759094238,-15.436738014221191,-15.22349739074707 -2155,2155,L137M,-0.00460215,-0.01866199,-0.08038719799999999,-0.025088762,-0.14725794,0.058706720999999996,0.011762048,-0.020966347,0.21901946,0.012652848000000001,-0.049976828,-0.117599698,-0.043174697000000005,-0.035911119,-0.014266404,-0.121061781,-0.17345409899999997,1.654077292,2.5155582969999997,-4.847081284,-5.139874443,-4.474568428,-4.352966621,-4.964768867,-5.303228058,-4.979974167,-2.0903621880000003,-6.71384859085083,-7.126280784606934,-7.859035968780518,-7.34286642074585,-7.174012660980225 -2156,2156,L137N,-0.034257837,0.015508491000000001,0.008805354,-0.97297948,-2.765156307,0.055053434000000005,-0.0062823290000000006,-0.062233345,0.029963222999999997,0.067016575,-0.035999592999999996,0.020146615,-0.002535908,-0.512136259,-1.4338227,-2.051826645,-3.478485969,1.715318251,1.373429946,-13.321713800000001,-13.66070147,-12.71609892,-14.67506841,-12.11220952,-13.44449068,-10.171095,-9.715937357,-11.136159896850586,-14.717232704162598,-12.926775932312012,-14.399496078491211,-13.897737503051758 -2157,2157,L137Q,-0.040344377,0.00040302199999999995,-0.07072099400000001,-0.505934979,-2.0692031969999998,0.054967972999999996,-0.037559413,-0.04312934,0.081115746,-0.015649736,0.016455779,-0.097816642,-0.043625345,-0.157886805,-0.8539831520000001,-1.76315697,-2.375249424,1.198357464,1.3468867709999999,-11.12768213,-11.81137198,-11.33487238,-11.62717197,-8.484181305,-12.380813,-7.501002281,-2.888098375,-10.205584526062012,-12.281960487365723,-11.338761329650879,-11.03768539428711,-12.643013954162598 -2158,2158,L137P,-0.018884048,-1.468272325,-2.020665783,-2.22412534,-2.743316825,0.066169539,-0.013662921000000001,-0.024105174,0.27741039100000003,-1.496621212,-1.4399234369999998,-1.8986904480000002,-2.1426411169999997,-2.061781355,-2.386469324,-2.572463944,-2.914169706,-0.408588164,-0.899299996,-13.17848505,-13.54812634,-12.93964551,-13.71106385,-12.345912599999998,-13.34767696,-10.171095,-9.715937357,-13.10135269165039,-14.44649600982666,-16.2591552734375,-13.532151222229004,-12.559819221496582 -2159,2159,L137S,-0.053561657,0.003637545,-0.019523197,0.001497737,-1.799622821,0.08319233,-0.026517658,-0.080605655,0.09123288,0.028099724,-0.020824635,0.016222999,-0.055269393,0.060843612000000005,-0.05784813900000001,-1.582282489,-2.0169631519999998,0.44026499700000005,1.30604665,-9.802663397,-10.29355078,-9.505205582,-10.50366345,-9.044688286,-9.666208885,-7.0576053860000005,-4.443296035,-10.408649444580078,-13.336421966552734,-13.752771377563477,-12.274642944335938,-13.236075401306152 -2160,2160,L137R,-0.057799387,-0.822449487,-1.92787599,-2.474269126,-2.957709252,0.067388749,-0.035646852,-0.07995192200000001,0.302964495,-0.63032153,-1.0145774440000002,-1.936251189,-1.919500791,-2.282063934,-2.666474317,-2.69508187,-3.2203366339999997,0.164576139,-0.5428212370000001,-12.36927197,-12.13331377,-12.2946601,-13.15176981,-10.78019717,-13.48641898,-7.99496215,-4.655326925,-13.425817489624023,-15.077571868896484,-13.037714958190918,-14.145339965820312,-14.381446838378906 -2161,2161,L137T,-0.012596648,-0.031520482999999995,-0.01765207,-0.003388147,-1.083467725,0.038812558,-0.023216565,-0.0019767310000000002,0.37580556299999995,-0.039194553,-0.023846412,-0.028570123,-0.006734016999999999,-0.004822058,-0.0019542360000000003,-0.8461328579999999,-1.320802592,0.48939432200000005,1.345857211,-7.688504807,-8.000066413999999,-9.032793381,-7.214277602999999,-6.977488815,-7.21789782,-5.724993662999999,-3.661306259,-9.701532363891602,-12.067879676818848,-12.70097541809082,-11.366920471191406,-11.694572448730469 -2162,2162,L137W,-0.07665665299999999,-0.028338846,-0.017399263999999998,-1.4875077019999998,-2.888567291,0.042404742,-0.057745791,-0.095567514,0.19836765399999998,0.025985205,-0.082662897,0.013834523,-0.048633051,-1.095151733,-1.8798636709999998,-2.464886798,-3.312247783,0.645899981,0.732335813,-11.05812986,-10.85102834,-9.857675934,-12.8840747,-9.449468887,-12.24840146,-7.254605268,-4.505841748,-9.915223121643066,-14.95048713684082,-14.184175491333008,-13.405582427978516,-13.050270080566406 -2163,2163,L137V,0.0014342489999999999,0.017019573,0.012496782,0.0011468510000000002,-0.698817295,0.023071781,-0.004336339,0.007204836,-0.053011012,0.030554849,0.003484297,-0.002203665,0.027197229,0.010547091000000001,-0.00825339,-0.546822623,-0.8508119670000001,0.676998478,1.417117489,-5.499788724,-6.183608322,-6.523427696000001,-4.395052444,-4.022797218,-6.374057937999999,-5.422165484,-2.414711155,-7.8404741287231445,-11.055868148803711,-9.672091484069824,-9.472213745117188,-8.96651554107666 -2164,2164,L137Y,-0.038573701,0.007598906,-0.062500844,-0.019695795,-0.46206087,0.19294429800000001,-0.030018146000000002,-0.047129255999999994,0.029963222999999997,0.026225927000000003,-0.011028116000000001,-0.037343034,-0.087658654,-0.021549782000000003,-0.017841807,-0.349892162,-0.574229577,1.306619061,1.8908595780000002,-10.98657814,-11.53160198,-10.32337232,-12.60866045,-9.083337936,-11.38591801,-7.0166262,-4.612125506,-8.784399032592773,-13.611889839172363,-13.436400413513184,-11.34945297241211,-11.15174388885498 -2165,2165,T138A,0.047300826,0.033895921,0.03309556,0.037385547000000005,0.009399046,-0.033673406,0.023038812000000002,0.07156284,-0.018499736,-0.007626371,0.075418212,0.025814936,0.040376184,0.021642391,0.053128703,-0.0072014290000000005,0.025999521,1.1984599329999999,2.588343014,-0.619875897,-0.7021566309999999,-0.204951721,-0.380359764,-0.907214874,-0.904696495,-2.748109517,1.476183038,-2.2812318801879883,-2.050630569458008,-2.7250218391418457,-3.1214141845703125,-3.2486324310302734 -2166,2166,T138C,0.031323059,0.031112032,0.07031865400000001,0.09050691,-0.34071976,0.041745902,0.048508617999999996,0.0141375,-0.022660938,0.03477586,0.027448204,0.016868872,0.123768435,0.091473198,0.089540621,-0.13738056099999998,-0.5440589579999999,1.16738291,2.1103258559999998,-5.701370988,-4.881204811,-6.029146202000001,-5.853961655,-5.848124725,-5.894417549,-7.082669196,-3.73963013,-8.319490432739258,-9.459779739379883,-7.8288774490356445,-8.030855178833008,-9.380279541015625 -2167,2167,T138E,0.043012374000000006,0.029564128,0.061262831,0.06456846299999999,0.009167938,0.04549634599999999,0.020852711,0.065172037,-0.021144134,-0.061684693,0.120812949,0.07540983700000001,0.047115824,0.092176001,0.036960925,0.017746939,0.000588937,1.252694668,2.763475511,-0.11589046300000001,-0.711804497,-0.214925835,0.509771454,0.285982018,-0.448475456,-1.8714484059999998,1.7933604369999998,-3.1189088821411133,-4.694925308227539,-1.4337431192398071,-5.7401251792907715,-3.5450854301452637 -2168,2168,T138D,0.04518757599999999,0.0103214,0.04738805,0.032292424,-0.03346632,-0.01512057,0.035489412000000005,0.054885739,-0.023030752,-0.036762645,0.057405445,0.024052762000000002,0.070723337,-0.000714056,0.06529890299999999,0.032118804,-0.099051444,1.195477376,2.8057874419999997,-1.251198177,-0.9184489290000001,-1.446336235,-1.24758419,-0.73636747,-1.907254059,-3.011889671,2.283162135,-3.184070110321045,-4.5136189460754395,-1.9027220010757446,-6.230824947357178,-4.708058834075928 -2169,2169,T138G,0.012043052,0.016113486,0.022302798,0.044071208,-0.000496644,-0.029698976000000002,-0.017221534,0.041307637,-0.019880025,-0.005029777,0.037256748,0.037313069,0.007292526,0.053595372,0.034547043,-0.019656159,0.018662872,1.6804900280000001,3.618873133,-3.0200615460000004,-1.6325158919999998,-3.15940416,-3.494865265,-2.426443985,-4.38707843,-3.9332418789999997,0.493101668,-3.380255699157715,-4.565944194793701,-3.723247528076172,-5.41212797164917,-4.727276802062988 -2170,2170,T138F,-0.10933271800000001,-0.10107327699999999,-0.030072788,-0.032378236,-0.20625038,0.004086483,-0.131105323,-0.087560112,0.00703297,-0.013094493,-0.18905206100000002,0.04975692,-0.109902496,0.018471374,-0.083227845,-0.092780228,-0.31972053100000003,1.280358879,2.291602782,-5.8896743670000005,-5.996547592000001,-6.5560890579999995,-6.237256682999999,-4.569076958,-6.089401542999999,-6.919952167000001,-3.801646251,-7.362726211547852,-9.203237533569336,-8.696004867553711,-9.128742218017578,-7.86729097366333 -2171,2171,T138I,0.088651516,0.09099836800000001,0.100352447,0.10238914199999999,-0.022101147999999998,0.023902534,0.07989803200000001,0.097404999,-0.016398604,0.059483755,0.12251298099999999,0.11257063099999999,0.088134263,0.051854234000000006,0.152924049,-0.029806966,-0.014395328999999998,1.182217169,2.487005351,-6.503337865,-6.738075821,-6.88703685,-7.085261696,-5.580189926,-6.2261250310000005,-7.578886262999999,-4.6686912419999995,-7.135721206665039,-8.66110610961914,-7.778629302978516,-7.639268398284912,-7.363986492156982 -2172,2172,T138H,-0.0028232829999999998,-0.032448141,0.066558357,0.035001093,-0.048618792,0.026129749,-0.031164378,0.025517812,0.003584874,0.046157808,-0.11105409,0.086593031,0.046523682999999996,0.074526768,-0.004524582,0.052710358,-0.149947942,1.0295571959999998,2.74375402,-3.2588947139999997,-2.937899055,-4.229243988,-2.903146004,-1.861804543,-4.362379982,-3.662103498,-0.181824249,-3.86979341506958,-5.996489524841309,-4.398937225341797,-6.523776531219482,-4.941175937652588 -2173,2173,T138K,0.18876250100000003,0.127911637,0.17258073699999998,0.140823749,0.081894723,-0.163015759,0.171044082,0.20648091899999998,0.069320617,0.136096794,0.11972648,0.109039762,0.23612171199999998,0.135647568,0.145999929,0.140520255,0.023269191,1.012074933,2.9732117689999997,-0.74079278,-0.754550018,-1.32689975,-0.413400566,-0.12274730699999999,-1.0863662570000001,-2.18914918,1.5212771019999998,-1.2950246334075928,-4.364310264587402,-2.1411943435668945,-5.302216529846191,-1.8423959016799927 -2174,2174,T138M,0.063857459,0.027988403999999998,0.110062385,0.09515017199999999,0.003602955,-0.000510161,0.085296355,0.042418563,0.060945994,0.059049678,-0.00307287,0.130048142,0.090076628,0.108417915,0.081882429,0.047911475,-0.040705566,1.054790213,2.757281957,-6.478669883999999,-6.622152229,-6.7187331089999995,-6.883342415,-5.842077712999999,-6.3270439529999996,-7.486823557999999,-4.785134558,-6.246366024017334,-7.963264465332031,-7.032871246337891,-8.069747924804688,-7.001975059509277 -2175,2175,T138L,0.035639024,0.006976589,0.073702054,0.09896232199999999,-0.04413855,0.032603291,-0.019598089,0.090876136,-0.051850585,0.027868592999999997,-0.013915415,0.078398552,0.069005556,0.09178867800000001,0.106135966,0.003774597,-0.09205169699999999,1.1910484890000002,2.822820842,-5.143076768,-5.719406349,-5.926114997999999,-5.7391971360000005,-4.259243896,-4.071421463,-6.157196101,-2.419191085,-6.416261672973633,-8.089271545410156,-6.776162147521973,-7.870982646942139,-6.815911293029785 -2176,2176,T138N,0.101419925,0.078614015,0.098621125,0.138190956,-0.011422068999999998,-0.046585455,0.041236768,0.161603081,-0.01257805,0.051045362000000004,0.106182667,0.109185035,0.08805721400000001,0.183161729,0.093220182,0.10086023599999999,-0.123704374,1.080463619,2.978678781,-1.25742303,-1.180660187,-1.5125796969999998,-1.140663269,-0.6887606959999999,-1.7644513019999999,-3.869707775,0.460018717,-2.7103238105773926,-4.605411052703857,-2.961768627166748,-5.472565174102783,-3.969647169113159 -2177,2177,T138Q,0.0034842659999999998,-0.039107189,0.0927326,0.10796978800000001,-0.022462671,0.138802931,-0.030004657999999997,0.036973189,-0.050265497,0.005126093,-0.08334047,0.062131821,0.123333379,0.04754547,0.16839410600000002,0.006952867,-0.051878209,1.462503487,2.934736795,-1.465633731,-1.7606166380000001,-1.986450806,-1.290158478,-0.871731934,-1.4192108,-2.569861971,0.317770603,-3.18748140335083,-4.6933183670043945,-2.7966103553771973,-6.111719131469727,-3.416390895843506 -2178,2178,T138P,-0.01933727,-0.003135185,0.032505371,0.023976012,-1.637176164,0.093063421,-0.026334899,-0.01233964,-0.05373330000000001,0.0006300219999999999,-0.006900391,0.060587192000000005,0.00442355,0.05522816,-0.007276136999999999,-1.460567173,-1.813785154,0.133562332,1.300167792,-4.711331203,-4.730882118,-4.86491111,-4.168256203,-3.697396065,-6.095210517999999,-4.723126262,-0.49626545899999996,-3.4943652153015137,-5.449459075927734,-4.862929821014404,-4.7869181632995605,-3.8935439586639404 -2179,2179,T138S,0.028018352000000003,0.026674087000000003,0.056585435,0.037171261000000004,-0.005663247,-0.011422953999999999,-0.004388116,0.06042482,0.0035869409999999997,-0.013252228999999999,0.066600403,0.053957973,0.059212895999999994,0.032250088999999996,0.042092433,-0.017987559,0.006661065999999999,1.285028742,2.621503574,0.11408441,0.445953514,-0.157487549,-0.041675995,-0.258152901,0.581784981,-0.7458139359999999,0.231032293,-2.694838047027588,-2.062563896179199,-2.513625144958496,-2.898573398590088,-3.6511993408203125 -2180,2180,T138R,0.040804709,0.011912368999999999,0.069178457,0.067143603,-0.014866236000000001,-0.045333987,-0.010243179,0.091852596,-0.046667684,0.023845137000000002,-2.0399999999999998e-05,0.066280107,0.072076807,0.08920708699999999,0.045080117999999995,0.018303719,-0.04803619,1.6804900280000001,3.618873133,-2.406187067,-1.454644073,-3.4805017780000003,-3.049792625,-0.69397155,-3.352025307,-3.618059727,2.275344989,-3.0482330322265625,-5.255248546600342,-2.763794422149658,-5.718305587768555,-4.402809143066406 -2181,2181,T138W,0.037425821,0.035226216,0.032468781,0.074664026,-0.048985812999999996,-0.037772997,0.010948853,0.063902788,0.035052982999999996,0.017582098,0.052870334000000005,0.050834868,0.014102693999999999,0.056105197999999995,0.09322285300000001,0.018793376,-0.116765001,1.2346776529999999,2.7720365339999997,-6.049598035,-5.256636841000001,-6.253641373,-6.571203102,-3.9765164719999997,-8.189992386,-6.13662106,-2.0268323169999998,-7.667454719543457,-10.945934295654297,-8.91584587097168,-9.88797378540039,-9.798097610473633 -2182,2182,T138V,-0.0077818290000000005,0.008948164,0.0025209620000000003,0.014650848999999999,-0.070479439,0.00930826,-0.017767595,0.002203937,0.04425778,-0.014206189,0.032102517000000004,0.015230802,-0.010188878,0.039015203,-0.009713505,-0.053140767,-0.08781811,1.151075495,2.271329932,-4.500710762,-4.95806839,-4.431795967,-5.18366317,-3.369942093,-4.56008419,-5.559889028,-2.198940296,-5.517740726470947,-6.96111536026001,-5.633677005767822,-6.636552810668945,-5.998237609863281 -2183,2183,T138Y,-0.042695915999999993,-0.015842156,0.09089455800000001,0.043143909,-0.063154918,-0.039259692,-0.068316717,-0.017075115,0.01703859,0.019052382,-0.050736694000000006,0.124309034,0.057480080999999995,0.12422468,-0.037936863,-0.001711975,-0.12459786099999999,1.248566977,2.72936441,-5.565269262999999,-5.387578673999999,-6.194828827,-5.440557869,-3.9275740810000004,-6.875806862,-5.826258987999999,-2.98310817,-5.860050201416016,-8.770811080932617,-7.915851593017578,-8.338549613952637,-7.47891902923584 -2184,2184,T139A,-0.068814666,-0.084822052,-0.028455638,-0.061575804000000005,-0.021554077,-0.006237436999999999,-0.046789933,-0.090839399,-0.07722349099999999,0.016809625,-0.18645372899999998,0.046408019,-0.103319294,0.055367005999999996,-0.17851861300000002,-0.001767815,-0.041340338,1.124142478,2.527128261,-1.7044294309999999,-1.263338905,-1.353040962,-2.19481002,-1.7556530380000002,-1.95530423,-3.099639194,0.594066046,-2.5960042476654053,-6.384336471557617,-6.206966400146484,-4.792633056640625,-4.616396903991699 -2185,2185,T139C,-0.038255576,-0.024917526000000002,0.00944258,-0.01251257,-0.169138366,0.10583220800000001,-0.025060911,-0.05145024,-0.012773968,0.046075772,-0.095910824,0.110043747,-0.091158587,0.11570486099999999,-0.14073,-0.090883428,-0.247393303,1.147806515,2.2973316980000003,-8.001510944,-6.596403114,-8.006027832000001,-8.985307495,-8.877137398,-7.5426788789999994,-7.353744607,-3.600680694,-7.500635147094727,-11.425296783447266,-7.606576442718506,-8.87493896484375,-7.718466758728027 -2186,2186,T139E,0.012108842,-0.013135738999999999,0.049405877,0.015980112,0.053101457000000005,-0.050680974000000004,0.012814103,0.011403581000000001,-0.014195555,0.06727843900000001,-0.093549917,0.078359691,0.020452062,0.07627919,-0.044318965999999994,0.09944827,0.006754643,1.266944575,3.040825888,-5.6800548189999995,-4.043139641000001,-6.1179767,-7.631993713,-6.273864815,-4.333299225,-4.953453838,0.96762564,-4.018895149230957,-8.872092247009277,-5.860381126403809,-7.604143142700195,-6.365273952484131 -2187,2187,T139D,-0.041222175,-0.054091245,0.024893093999999998,0.027184041000000003,-0.217867719,-0.001273039,0.020034042,-0.102478391,-0.012282685,0.029811927999999998,-0.13799441699999998,0.09040210900000001,-0.040615922,0.128451132,-0.074083051,-0.087673283,-0.348062155,1.402202694,2.575328355,-7.887607301,-5.249495743,-8.858196541,-8.904714287000001,-9.406368323999999,-7.019261612,-6.292161615,-0.971276204,-5.4929704666137695,-8.774890899658203,-7.098974704742432,-9.064746856689453,-7.33834981918335 -2188,2188,T139G,-0.033385256,-0.071951285,-0.027303179,-0.042742404000000005,-0.11763835199999999,-0.023782131,-0.014934061,-0.051836451,-0.031479599,-0.021917256,-0.12198531300000001,-0.006612505,-0.047993852999999996,0.033266076,-0.118750884,-0.077655636,-0.157621067,1.339728546,2.4291681730000003,-4.869552748,-4.109223595,-4.39698864,-5.069132408,-6.063202782,-4.709216316,-5.200381608,-2.146168406,-4.448348045349121,-7.450070858001709,-7.260610580444336,-7.673137664794922,-6.807332992553711 -2189,2189,T139F,-0.085580215,-0.064471739,-0.016598821,-0.073303858,-1.379021899,0.020416706,-0.07899041400000001,-0.092170016,-0.046436303,-0.041392685,-0.08755079199999999,-0.006269869,-0.026927773,0.013806738999999998,-0.160414455,-1.247995213,-1.510048584,0.671421705,1.333507755,-8.977303757,-8.195932915,-9.480024185,-9.597422218,-9.69720137,-7.915938095,-6.22776193,-1.050381707,-5.399752616882324,-11.070161819458008,-8.28672981262207,-10.258845329284668,-7.967073917388916 -2190,2190,T139I,-0.101361972,-0.046653365999999995,-0.032759277,-0.079258122,-0.035725821,-0.035481083,-0.096387961,-0.10633598300000001,0.014339796,0.045102092999999996,-0.138408824,-0.0006949110000000001,-0.064823643,0.029548513,-0.18806475600000003,0.00250707,-0.073958711,1.244514001,2.707780622,-7.272871365,-5.4955096889999995,-8.765267921,-7.857451537999999,-7.962367828,-6.28375985,-5.895342155,-0.329813973,-6.543228626251221,-10.756685256958008,-8.250179290771484,-8.924482345581055,-8.572357177734375 -2191,2191,T139H,-0.11503412,-0.132290938,-0.081671372,-0.106540068,-0.33664360299999996,-0.027777918,-0.112495156,-0.11757308400000001,-0.046861099999999996,-0.08177184700000001,-0.18281002899999999,-0.019938002,-0.143404741,0.009718898,-0.222799033,-0.23493169100000003,-0.438355515,1.8090060730000002,2.424468709,-4.770661147,-4.918910202,-4.298344734,-5.359063507,-5.878014618,-3.3989726719999998,-5.168105079,-0.314568917,-5.377190113067627,-8.51050090789795,-6.798346519470215,-8.310858726501465,-5.948064804077148 -2192,2192,T139K,0.049809395,-0.07677987900000001,-0.011363966000000001,-0.019848901000000002,-1.1341245709999999,-0.000677767,0.066716829,0.03290196,-0.033428787,-0.033423755,-0.12013600199999999,-0.06875932,0.046031388,0.05150496,-0.091202761,-0.971251605,-1.296997537,0.65130628,1.351647927,-4.853296548,-4.029463821,-3.425359406,-5.9259255070000005,-5.662410675,-5.223323334,-3.491674984,0.253644947,-6.364291667938232,-9.841976165771484,-7.879824161529541,-8.286140441894531,-7.73855447769165 -2193,2193,T139M,0.0076139169999999996,-0.09064492800000001,-0.012907674,0.028126169,-0.095383625,-0.057320323,-0.015770139,0.030997972000000002,-0.08882917300000001,0.0038188659999999998,-0.185108722,0.027951478999999998,-0.053766826,0.08463101599999999,-0.028378679,-0.028609887,-0.162157363,1.361151851,2.6363844690000002,-7.465278989,-5.680759407,-8.31283355,-9.44532695,-7.044448868,-6.843026169,-5.589018082000001,-0.6724230999999999,-5.09407377243042,-9.231882095336914,-8.385627746582031,-8.309962272644043,-7.1551513671875 -2194,2194,T139L,-0.066674262,-0.11065359,-0.008909528,-0.058212858,-0.040313798,-0.0018838479999999998,-0.050620774,-0.082727749,-0.02180566,-0.008000286,-0.213306893,0.01991538,-0.037734435,0.065571084,-0.1819968,0.031705481,-0.11233307599999999,1.169188176,2.8064546289999996,-7.335669307000001,-5.4061295320000005,-8.432587692,-8.07676017,-9.124375587000001,-5.638493552999999,-4.093426698,1.766956728,-4.542603492736816,-9.476897239685059,-7.700040817260742,-8.302438735961914,-7.261066913604736 -2195,2195,T139N,-0.036150597,-0.061296354000000004,0.0044178740000000005,-0.01934973,-0.08169222200000001,-0.077122364,-0.029644077,-0.042657117,-0.049151488,0.00799909,-0.13059179699999998,0.019685427,-0.010849679,0.04908873,-0.087788189,-0.056070283,-0.10731416099999999,1.2133435590000001,2.3989563869999997,-4.289839668,-3.072246208,-4.7381367260000005,-4.78121582,-5.543461174,-3.3141384119999997,-5.260512516,-1.7493460230000002,-5.780553817749023,-6.3784685134887695,-6.776360988616943,-6.977123260498047,-6.017251968383789 -2196,2196,T139Q,-0.007160631999999999,-0.092551175,0.027528917000000003,-0.009708671,-0.02812127,-0.020176265,0.030082223999999998,-0.044403488,0.095107619,-0.0026794270000000003,-0.18242292300000001,0.037190215,0.017867618000000002,0.10425724,-0.12367458099999999,0.07076755,-0.127010089,1.210047111,2.96515002,-4.957104672,-4.529134132,-4.366084723999999,-5.959701355,-6.028862792999999,-3.9017403560000004,-4.105781196000001,0.31279392,-4.783888816833496,-8.341463088989258,-6.509500503540039,-7.5670857429504395,-6.013064861297607 -2197,2197,T139P,-0.08103953700000001,-0.050579470999999994,-0.021264476,-1.3472554190000001,-2.120888247,0.048276014000000006,-0.047742680999999995,-0.114336392,-0.022486701,0.008828978000000001,-0.109987919,0.021271925,-0.06380087599999999,-1.045726758,-1.6487840790000001,-2.20208922,-2.039687273,2.083473241,1.4230199019999998,-6.112336207999999,-4.714641647,-6.524118422999999,-7.468125092,-6.6979776,-5.156818275,-6.703137936,-3.511979155,-10.651480674743652,-9.335537910461426,-10.668745040893555,-9.3668212890625,-10.427556991577148 -2198,2198,T139S,-0.044946522999999995,-0.064014906,0.00019114299999999998,-0.03940912,0.024660069,-0.036218837000000004,-0.036996968,-0.052896077,-0.035628087999999995,0.0018025889999999998,-0.129832401,0.066506864,-0.066124578,0.07627919,-0.15509743,0.062573643,-0.013253506000000002,1.067914636,2.733284345,-0.820967345,-0.372434471,-0.534967979,-1.097303017,-1.240348564,-0.859782692,-2.638117652,0.186264688,-2.4116406440734863,-2.9841108322143555,-3.151839256286621,-3.383063316345215,-1.9925541877746582 -2199,2199,T139R,-0.052422042,-0.059192942000000005,-0.0016262689999999998,-0.02455481,-0.18923676,0.011926443,-0.035388666,-0.069455418,-0.022998914,0.025477312999999998,-0.143863197,0.046365792,-0.049618329,0.059044661,-0.10815428,-0.097563625,-0.280909894,1.393694966,2.42738618,-3.6195950010000004,-3.290144119,-3.683483253,-4.289686134,-4.36979039,-2.464871109,-4.745185276,1.5298017780000002,-6.829994201660156,-9.533906936645508,-7.361712455749512,-7.900302410125732,-7.744456768035889 -2200,2200,T139W,-0.162740277,-0.137622911,-0.036385424,-0.11115719999999998,-1.634384635,0.061127460999999994,-0.147503133,-0.17797742,-0.012931833,-0.012435938,-0.262809883,0.020708501,-0.093479349,0.044665536,-0.266979935,-1.5474649390000002,-1.72130433,0.141842937,1.299659318,-9.61720569,-8.320450362999999,-9.399846443,-11.30443879,-10.26024358,-8.801049277999999,-6.739993601,-2.864572243,-7.311708450317383,-12.758907318115234,-10.673803329467773,-11.204999923706055,-10.335397720336914 -2201,2201,T139V,-0.074843635,-0.10531397099999999,-0.055796759,-0.055646363,-0.055610984,0.052907012999999996,-0.057064889,-0.09262238,-0.005331075,-0.001025076,-0.209602865,0.009613087,-0.121206605,0.064450547,-0.175743273,0.024368041,-0.135590008,1.146717002,2.694846918,-5.692967595,-4.864584244,-6.271646682999999,-5.785844902000001,-6.154010246,-5.3887519,-4.380703887,-0.31034032,-5.366367340087891,-9.882097244262695,-7.310689449310303,-7.3829264640808105,-7.766974449157715 -2202,2202,T139Y,-0.022793172999999996,-0.03330858,-0.008240303000000001,-0.036428688,-1.324513524,0.072833302,0.019599918,-0.065186263,-0.024926193,0.025004712000000002,-0.091621871,-0.008486739,-0.007993867,0.037975825,-0.11083319999999999,-1.193390513,-1.455636535,0.6279090270000001,1.33311386,-7.7514651,-7.402319672000001,-7.39843898,-9.13065213,-7.875870612999999,-6.950044106,-5.708911434,-0.381700702,-5.675984859466553,-9.938323974609375,-7.7870965003967285,-9.101749420166016,-7.281352996826172 -2203,2203,I140A,-0.06267311099999999,0.073692535,0.047544496,0.061307204000000004,-1.498297601,0.09263537300000001,0.0694177,-0.194763921,0.020994227,0.095606069,0.051779001,0.022903217000000003,0.07218577400000001,0.085816815,0.036797592999999996,-1.3731842580000002,-1.623410944,0.225454015,1.305838508,-4.391328032,-3.057601669,-4.291975555,-6.626827598999999,-4.118591888,-3.861643448,-4.459707736,-1.145191496,-7.390434741973877,-8.834686279296875,-7.12608003616333,-9.499438285827637,-8.529125213623047 -2204,2204,I140C,0.060230927000000004,0.020351479,0.022412615,0.012819656,-1.437943051,0.072517243,0.052623242,0.067838611,0.03339708,0.036575926,0.004127031,-0.001297593,0.046122822,0.041573634,-0.015934323,-1.2849749259999999,-1.5909111759999999,0.673691796,1.331636422,-7.0517802960000004,-5.2951173780000005,-6.284349487,-10.78031923,-6.803809967,-6.09530542,-6.064350748,-3.71908382,-10.297904014587402,-10.325723648071289,-8.532753944396973,-10.7666597366333,-9.50306224822998 -2205,2205,I140E,0.069990676,0.016015876000000002,-0.024020345,-1.312140447,-2.106084455,-0.001810865,0.079196425,0.060784927,0.063619971,-0.019683944,0.051715695,-0.02543609,-0.022604599,-1.160437143,-1.46384375,-2.098440118,-2.113728792,2.248885612,1.493137515,-9.076833817999999,-6.8742016679999995,-9.031281273,-12.42086936,-8.773223418999999,-8.284593369,-8.094582497000001,-6.534454729,-13.346349716186523,-12.498175621032715,-9.704681396484375,-12.391777038574219,-9.651101112365723 -2206,2206,I140D,0.03945061,-0.082263398,-1.409062161,-2.2373470109999998,-3.26519342,0.034310776,0.056096632,0.022804587999999997,0.010831252,-0.035594947,-0.12893184800000002,-1.1936309390000002,-1.6244933819999998,-2.151536584,-2.323157437,-2.98039509,-3.54999175,2.162399835,0.7663971559999999,-10.22404447,-7.985114014,-9.895039581,-14.16392251,-9.902371283999999,-9.173774963,-8.834125656,-8.932049556,-13.820575714111328,-12.98482894897461,-11.175907135009766,-12.548727035522461,-9.522332191467285 -2207,2207,I140G,0.018111691,0.007052981999999999,-0.00685681,-1.010761062,-1.734219462,0.06500602400000001,0.065852203,-0.029628822000000003,0.025782821,-0.014947803999999999,0.029053767999999997,-0.054695415,0.040981795,-0.633551552,-1.387970572,-2.024961508,-1.443477415,1.836396175,1.4121174459999999,-7.442145476,-6.192971458,-6.933194893,-10.33661476,-6.522277442999999,-7.2256688229999995,-5.912435102999999,-3.97427313,-11.841085433959961,-12.94468879699707,-11.2381591796875,-13.639551162719727,-10.538908004760742 -2208,2208,I140F,0.099751373,0.035192389,0.058018158,0.048891695,-0.18441350399999998,-0.043800654,0.112191326,0.08731142,0.029792955,0.03247182,0.037912957000000004,0.067053782,0.048982532999999995,0.046496311,0.051287079000000006,-0.146057545,-0.222769462,1.3556879290000001,2.250613978,-4.551839363,-3.3718334660000004,-3.707402824,-7.374999855,-4.147935242,-4.157025429,-3.925736096,-1.757039035,-6.458631992340088,-4.651381015777588,-6.452846527099609,-5.176301002502441,-4.175424575805664 -2209,2209,I140H,0.053201451,0.016202885,-0.010349353,-1.352290775,-2.596333523,0.043106427,0.066838884,0.039564018,0.02484058,-0.009077489000000001,0.041483259,-0.02148576,0.0007870539999999999,-0.9720121490000001,-1.7325694,-2.129174735,-3.06349231,2.074338269,1.4305973140000001,-9.007478189,-6.092997498,-8.213595444,-14.82009936,-8.110594025,-7.800104622,-5.785983348999999,-4.604322027,-11.846431732177734,-9.57972526550293,-9.15418815612793,-10.325780868530273,-8.127276420593262 -2210,2210,I140K,-0.019354467,0.009653039,-0.755288815,-1.583831486,-2.431673968,0.014636233,-0.0176,-0.021108934,0.010156657,0.016915291000000002,0.002390787,-0.545351194,-0.965226435,-1.62751646,-1.540146512,-2.678223715,-2.18512422,1.8908223530000001,0.9345785040000001,-9.948549683,-7.993138504,-9.691270615,-13.35750648,-9.368353477000001,-9.33247934,-8.834125656,-8.932049556,-14.056705474853516,-13.200883865356445,-12.32907772064209,-13.652669906616211,-10.939002990722656 -2211,2211,I140M,0.08725681699999999,-0.008758017,0.008632844,0.007953198,-0.036978727999999995,-0.018402044,0.091133522,0.083380112,0.044295304,0.008393905,-0.025909937999999997,0.0047379679999999995,0.012527719,-0.047732863,0.063639259,-0.076297373,0.002339917,1.340737958,2.341323869,-3.029273608,-2.727958183,-3.076508118,-2.9337780689999997,-2.882379715,-3.525743958,-4.282813613,-2.341671581,-6.890573501586914,-6.4863409996032715,-6.756877899169922,-6.928253173828125,-6.266630172729492 -2212,2212,I140L,0.07648165,0.023758592999999998,0.027289617999999998,0.010490571,0.024254683,-0.013618403999999999,0.06943971,0.08352358900000001,0.052960821,0.007124233000000001,0.040392952,0.000148639,0.054430597000000004,0.007452816,0.013528326,0.031525135,0.01698423,1.165838882,2.697555098,-0.387422964,0.130186623,-0.221735603,-0.325719231,-1.1021122970000001,-0.417734314,-1.992379022,0.698512293,-3.900193214416504,-3.600099563598633,-5.020705223083496,-1.8329777717590332,-4.145486831665039 -2213,2213,I140N,0.060406195,-0.016507451,-0.023164344,-1.042676006,-2.209628613,-0.007546703,0.071725777,0.049086613,-0.06634222299999999,-0.039693207,0.006678306,-0.067175222,0.020846535,-0.4994415,-1.5859105119999999,-1.93236598,-2.486891245,1.667191505,1.389788981,-8.558362178,-6.272047424,-8.384725624,-12.82717556,-8.061089516000001,-7.246772766,-6.775764958,-5.464381679,-12.645051956176758,-11.706201553344727,-9.601831436157227,-11.187488555908203,-8.672111511230469 -2214,2214,I140Q,0.03940386,0.002884432,0.00332688,-0.01836465,-1.4192500559999999,0.047185677,0.020449731000000002,0.058357988,0.052300295999999996,-0.008094344,0.013863208,-0.000470343,0.007124101999999999,0.039076823,-0.075806122,-1.509685594,-1.328814517,0.657442112,1.318723729,-7.314276936000001,-4.372728508,-7.600938065,-11.12410686,-6.80433931,-6.669271935,-5.912103146000001,-4.136170245,-12.1585054397583,-10.23978328704834,-9.556408882141113,-10.617982864379883,-9.152325630187988 -2215,2215,I140P,0.010490496,-0.5504080029999999,-1.739585811,-2.114375231,-2.74499476,0.052842994000000004,0.019451566,0.001529426,0.044033395,-0.306655117,-0.794160888,-1.967889199,-1.5112824230000002,-2.11961487,-2.109135591,-2.726624627,-2.763364892,1.062682211,-0.08540157599999999,-9.772675694,-8.273721886,-9.620288147,-12.69573434,-9.520983795,-8.752650307,-8.620421317,-8.089070996,-13.681008338928223,-12.423778533935547,-13.897468566894531,-9.72109317779541,-11.640238761901855 -2216,2216,I140S,0.014603686000000001,-0.0049878679999999995,-0.022106543,-0.107281797,-1.5636817159999998,0.049911566,0.022490512999999997,0.006716859,-0.013803886000000001,-0.020107364,0.010131628,-0.054945637,0.010732552,-0.027291702999999997,-0.18727189100000002,-1.709754833,-1.4176085980000002,0.776103442,1.315453593,-5.949923315,-4.545573433,-5.940417664,-8.94239341,-5.454378975,-4.866853096,-5.871575872999999,-3.341591662,-10.889193534851074,-9.4638032913208,-8.773707389831543,-9.830782890319824,-8.947940826416016 -2217,2217,I140R,0.036711934,-0.013907277,-0.650831056,-1.725957907,-2.684032739,0.06657091400000001,0.04275538,0.030668487,0.018860243999999998,-0.020024701000000002,-0.007789853,-0.417364764,-0.8842973479999999,-1.5731587969999998,-1.8787570169999999,-2.2310656840000003,-3.136999794,1.7427628659999999,0.9015630029999999,-9.9022347,-7.218070793,-9.818572411,-14.10194305,-9.578620483,-8.793966766,-7.802581152999999,-6.534454729,-14.238805770874023,-12.405837059020996,-12.278942108154297,-12.629674911499023,-11.418001174926758 -2218,2218,I140T,0.039628878,-0.017652796000000002,0.018942399,0.014142285,-1.5231895969999998,0.074983535,0.066847596,0.012410158999999999,-0.011487941000000002,-0.009627795,-0.025677797000000002,-0.001511886,0.039396684,0.030898991,-0.002614422,-1.33385877,-1.7125204230000002,0.7960434759999999,1.33819361,-4.633910347,-3.53565287,-4.475618301,-6.287097206,-4.54070282,-4.330480537,-4.799573036,-2.0042849069999997,-9.197774887084961,-8.937920570373535,-7.911612510681152,-8.241246223449707,-8.21625804901123 -2219,2219,I140W,0.020466501,-0.004243987,0.006879734,-0.711455142,-1.753049544,0.079097235,0.055342815,-0.014409813,-0.09234814599999999,0.010445495,-0.018933468000000002,-0.021134384,0.034893852,-0.307455825,-1.1154544579999999,-1.9170430040000002,-1.589056084,1.3839272759999999,1.35019655,-9.60957867,-8.340267883,-8.889114082,-12.83318353,-9.056764656,-8.928563202000001,-8.834125656,-8.932049556,-10.964458465576172,-11.239903450012207,-11.661330223083496,-11.019659042358398,-9.825133323669434 -2220,2220,I140V,0.08842957,0.014856538999999998,0.036979587,0.010552858,0.015865042,-0.008646863000000001,0.080284825,0.096574315,-0.016226868999999998,0.008047181,0.021665897000000003,0.017817158,0.056142015,-0.016995573,0.038101288999999997,0.022987293,0.00874279,1.192579612,2.685602053,-1.100670506,-0.840864609,-0.857747787,-1.795814629,-1.41168927,-0.5972362370000001,-1.429142235,0.281730067,-4.871000289916992,-5.736632347106934,-5.654411792755127,-5.4495038986206055,-6.018034934997559 -2221,2221,I140Y,0.022035722999999997,-0.035699805,-0.027948017000000002,-0.033877028999999996,-0.643092522,0.031796354,0.036691048,0.007380398000000001,0.057789968,-0.026918409,-0.044481201,-0.062293021,0.006396987,-0.029867332000000003,-0.037886726,-0.472539218,-0.8136458259999999,1.49344939,1.86400115,-7.648501627000001,-5.55498674,-6.482398567000001,-12.13531704,-6.843241226,-7.22656456,-5.783980304,-3.684561085,-9.459342002868652,-8.091163635253906,-8.461459159851074,-6.384757041931152,-4.5828142166137695 -2222,2222,G141A,-0.016246767,0.054323404000000006,0.001276377,-0.00023113099999999998,-1.755335207,0.05171659,0.0031721640000000003,-0.035665697,0.043272874,0.010986265,0.097660543,-0.023356954,0.025909707999999997,0.014275963999999999,-0.014738226,-1.643029515,-1.867640899,0.699148322,1.314624099,-7.63416008,-7.494508286,-7.834208267,-7.800629227000001,-7.39154789,-7.649906731000001,-7.25189471,-6.22765299,-8.393726348876953,-8.702760696411133,-8.671473503112793,-9.375486373901367,-9.483561515808105 -2223,2223,G141C,-0.067496499,0.076379365,-0.016970974,-0.199595243,-1.746883758,0.075836246,-0.052881607000000004,-0.08211139099999999,0.098469907,-0.006895608,0.15965433699999998,0.038043312,-0.07198525900000001,-0.01304904,-0.386141445,-1.70021054,-1.793556975,0.7293857559999999,1.3140519609999999,-9.800131223,-9.637469994,-10.18542661,-9.706120689,-9.687845917,-9.7837929,-8.582593854,-8.656845841,-11.860997200012207,-11.933347702026367,-11.849654197692871,-11.502848625183105,-12.166890144348145 -2224,2224,G141E,-0.037855371,0.030800462,-0.052099047999999995,-0.02534532,-1.398896115,0.059927142999999995,0.01474989,-0.090460631,-0.09097872800000001,0.07950887400000001,-0.01790795,-0.02823143,-0.075966666,0.045263429,-0.095954069,-1.335423007,-1.462369223,0.759389395,1.3361049170000001,-6.445106844,-6.18060688,-6.998313004,-6.175407432999999,-6.73665741,-6.1345494920000005,-6.201491466,-5.921741667999999,-9.415985107421875,-9.399914741516113,-8.851839065551758,-9.962977409362793,-8.48527717590332 -2225,2225,G141D,-0.067909527,0.023840992999999998,-0.041156918,0.017771539,-1.723675786,0.092380768,-0.063617029,-0.072202025,0.122492774,-0.019056992,0.066738977,-0.111522539,0.029208703,0.020156564,0.015386513000000001,-0.889592688,-2.557758883,0.74743775,1.374396961,-3.873250647,-3.645155693,-4.115102348,-3.3584631810000003,-4.550142311,-3.6973897019999997,-4.7276631710000006,-3.616531635,-5.867598533630371,-7.259429931640625,-7.4808502197265625,-9.246902465820312,-8.171344757080078 -2226,2226,G141F,0.040114643,0.068174543,-0.00011464799999999999,-0.9846595909999999,-2.235048401,0.050692995,0.10563984,-0.025410555,-0.027751828,-0.021762885,0.15811197,-0.010247721,0.010018426,-0.605968859,-1.3633503219999998,-1.8533805159999999,-2.616716286,1.862528639,1.472809675,-11.38295504,-10.65978058,-11.98453452,-11.06583293,-11.00121209,-12.20341511,-9.345783834,-10.56086115,-14.722480773925781,-14.809890747070312,-13.260147094726562,-13.918701171875,-14.667378425598145 -2227,2227,G141I,-0.120222281,0.003405966,-0.0031094679999999998,-1.0250397820000001,-2.337303037,0.000638883,-0.135142129,-0.10530243199999999,-0.138450125,0.030373317,-0.023561386,0.083745405,-0.08996434,-0.305145032,-1.7449345319999998,-2.128603248,-2.546002825,1.5932854090000002,1.342960855,-9.135840883,-8.72706987,-10.40629797,-9.709876677999999,-8.356974762,-8.478985137999999,-7.45190376,-5.641960555,-13.856426239013672,-14.916193962097168,-15.364479064941406,-12.734318733215332,-13.704669952392578 -2228,2228,G141H,-0.013113225,0.03592757,0.021801546,0.038961832,-1.5860283990000001,0.123103545,0.040280937999999995,-0.066507388,0.023014483,-0.013211099999999998,0.08506624,0.004120059000000001,0.039483032,-0.005058099,0.082981762,-1.593743205,-1.578313592,0.75321606,1.320133877,-8.658708661,-8.415706467,-8.843847351,-8.626537529,-9.560872971,-7.846578987000001,-8.429084632999999,-7.998036452000001,-12.024177551269531,-10.791960716247559,-11.362225532531738,-12.090567588806152,-10.873608589172363 -2229,2229,G141K,-0.097789617,0.075817383,-0.014428483,-0.030623595,-1.367054306,0.057337930999999995,-0.057495494,-0.13808374,-0.231871811,0.055008364000000004,0.096626401,0.08426708,-0.113124045,0.074364019,-0.135611208,-1.399489102,-1.33461951,0.443429755,1.311898188,-5.733889723,-5.6194527889999994,-5.625838402,-6.093531197000001,-6.7042877579999995,-4.62633847,-5.427061537999999,-5.181346957,-11.19926929473877,-11.339997291564941,-11.42505168914795,-10.731578826904297,-9.946220397949219 -2230,2230,G141M,-0.046860513,0.039629861,-0.049201916,0.074906312,-1.532986606,0.016183909,-0.023508859,-0.070212167,-0.197212508,-0.034425429,0.113685151,-0.093884543,-0.004519288,0.024891897000000003,0.124920726,-1.59977517,-1.466198041,0.703867818,1.315950193,-10.55450373,-9.987561592,-11.04544693,-11.49914362,-10.07782359,-10.16254291,-8.596394802999999,-8.088402807000001,-14.485587120056152,-14.593392372131348,-14.210545539855957,-14.51229476928711,-14.270069122314453 -2231,2231,G141L,-0.027995232999999998,0.089400842,-0.009828929,-0.164416401,-1.747878303,0.042055302999999995,0.005468728000000001,-0.061459192999999995,-0.050376448,0.050409876,0.128391808,0.000480356,-0.020138213000000002,-0.000468893,-0.328363908,-1.838945157,-1.656811448,0.8674374859999999,1.312620857,-10.11876252,-9.975550858,-10.52134386,-10.85500507,-9.790473366,-9.45143943,-8.133323921,-7.297633161,-13.664224624633789,-14.136953353881836,-13.576111793518066,-12.338013648986816,-13.768427848815918 -2232,2232,G141N,-0.069070313,0.005640695,-0.073310871,-0.158982193,-0.71373099,0.17508137199999999,-0.05054663400000001,-0.087593991,0.062424802,-0.148151688,0.159433078,-0.135881885,-0.010739857,-0.068589111,-0.249375275,-0.6749791740000001,-0.752482805,1.219871232,1.5654299980000002,-4.621586218,-4.784200836,-4.709714928,-4.649816223,-5.13473246,-3.8294666439999996,-5.102472371,-4.8906755319999995,-8.167810440063477,-9.048818588256836,-9.50760269165039,-10.436388969421387,-9.421202659606934 -2233,2233,G141Q,0.030117083,0.034721813,-0.07069142099999999,0.0028035770000000002,-1.174642188,0.081322023,0.078057512,-0.017823346,-0.10603854300000001,-0.036086213,0.105529839,-0.077061922,-0.06432092,0.03093033,-0.025323176,-1.476497217,-0.872787159,0.327345033,1.305208412,-8.104459341,-7.800983062999999,-8.03881192,-7.90984761,-8.740981842,-8.031672272,-7.645155712999999,-7.361082595,-11.899849891662598,-11.070244789123535,-10.934174537658691,-11.614984512329102,-10.190176010131836 -2234,2234,G141P,-0.053865984000000006,0.051472652,-0.018488252,-1.52972003,-2.550557496,0.040977972,-0.015435919,-0.092296049,-0.046656542999999995,0.008616366,0.094328938,-0.008498414000000001,-0.02847809,-1.290330393,-1.769109667,-2.438747657,-2.6623673340000003,0.973049756,0.7536675,-9.198641152999999,-9.502551041,-9.586049277999999,-8.821390938,-8.77016803,-9.313046478,-6.634202232000001,-3.6551321310000002,-13.908807754516602,-13.971437454223633,-14.761137008666992,-12.69314193725586,-13.282052040100098 -2235,2235,G141S,-0.034085452999999995,0.111418406,0.01903371,0.022590172000000002,-1.572262939,0.071782072,0.0004947,-0.06866560599999999,-0.061371697,0.09218046699999999,0.130656344,0.028549002,0.009518418,0.063902764,-0.01872242,-1.454797584,-1.689728294,0.5722636489999999,1.316109343,-5.90490287,-5.615930099,-6.465906853,-6.002451775,-5.627747498,-5.812478127,-5.340712795,-4.545116414,-9.226961135864258,-9.0052490234375,-8.984664916992188,-9.038793563842773,-9.302382469177246 -2236,2236,G141R,-0.040246135,0.023015558,-0.023955762999999998,0.001517167,-1.58238244,0.060374483,-0.016239311,-0.064252958,-0.055729670999999995,0.008035801,0.037995315,-0.020418905,-0.027492621000000002,0.015766437,-0.012732103,-1.6575146440000001,-1.507250236,0.8294104390000001,1.321010994,-6.788199446,-6.569435013,-6.964848137000001,-6.730031776000001,-7.886068817000001,-5.790613487000001,-6.2486321160000005,-5.4237736739999995,-12.240158081054688,-10.619194984436035,-11.223133087158203,-9.997806549072266,-10.153337478637695 -2237,2237,G141T,-0.057877541,0.012784463000000001,-0.014771596000000001,-0.246644058,-1.95731596,0.075194375,-0.108745552,-0.00700953,0.115250909,0.021779262,0.0037896640000000003,0.0027913720000000003,-0.032334563,-0.01390963,-0.479378486,-1.7845155380000002,-2.1301163819999998,0.7738183129999999,1.310477267,-7.45193616,-6.883353996,-8.065084167,-7.564050362000001,-6.811869484,-7.935322792000001,-6.47515324,-4.615081244,-12.061893463134766,-12.195993423461914,-11.097423553466797,-11.451153755187988,-10.916692733764648 -2238,2238,G141W,-0.022431573,0.01509296,-0.158098756,-1.542783045,-2.4720980569999997,0.11058718599999999,0.028921582,-0.073784728,-0.11802204599999999,-0.021819794,0.052005712999999995,-0.029515631,-0.286681881,-1.3098577470000001,-1.775708343,-2.514865555,-2.429330558,0.732670954,0.723729362,-10.7581419,-10.27614566,-10.90705335,-10.88416222,-11.07091641,-10.65243187,-9.328710494,-10.46766159,-14.241487503051758,-14.874905586242676,-13.244217872619629,-14.351704597473145,-12.896249771118164 -2239,2239,G141V,-0.02126953,-0.012338416999999999,0.000246538,-0.816436534,-1.844794396,0.055715277,0.044242888,-0.086781947,-0.006767336,-0.014170364,-0.01050647,0.0030067740000000003,-0.002513698,-0.24957356,-1.3832995080000001,-2.1416985459999998,-1.547890245,1.217750144,1.305482002,-8.306577269,-7.886409218,-9.533538818,-8.706027695,-7.682543655,-7.724366959,-6.833978881,-5.109497341,-11.579510688781738,-12.981903076171875,-13.36494255065918,-11.414776802062988,-11.656947135925293 -2240,2240,G141Y,-0.188018422,-0.021067377,0.037378392,-0.8526990870000001,-2.242010824,0.045803785,-0.172112347,-0.20392449699999998,0.19160812100000002,0.067505385,-0.109640139,0.177797352,-0.103040569,-0.09432044199999999,-1.611077731,-1.770845627,-2.71317602,0.956216725,1.3210392009999998,-10.08119046,-9.727016434,-10.88435323,-9.674218788,-10.11267155,-10.00769231,-8.459784056,-8.088402807000001,-13.47897720336914,-13.83820915222168,-13.186760902404785,-14.125244140625,-13.321565628051758 -2241,2241,G142A,-0.007918629,-0.034104733,-0.002959489,-0.715207921,-1.667980374,0.089995638,0.029380546,-0.045217803,0.043908665,-0.051147639,-0.017061826999999998,-0.056922065,0.051003087,-0.322812764,-1.107603077,-1.856181667,-1.479779081,1.461658809,1.370198966,-7.579718086000001,-7.250038185,-7.215907005,-8.476607567,-7.056878212000001,-7.899159462,-7.016289966,-6.273001337,-11.320535659790039,-10.242842674255371,-8.044288635253906,-8.332767486572266,-9.580774307250977 -2242,2242,G142C,-0.05076114599999999,-0.007245601,-0.11159738300000001,-1.6430326069999999,-2.370468153,0.158694287,-0.032475146,-0.069047145,-0.074871893,-0.061676275,0.047185074,-0.084060941,-0.13913382400000002,-1.20984229,-2.076222923,-1.977915264,-2.7630210410000005,2.642937279,1.8097818509999999,-11.14399873,-10.556320300000001,-11.39188991,-12.2497953,-10.29082924,-11.23115888,-9.35014905,-10.85705337,-14.634825706481934,-13.650472640991211,-11.431402206420898,-10.520686149597168,-13.561553001403809 -2243,2243,G142E,0.012007875,-0.014425225,-0.027715574,-0.085481208,-2.143842851,0.112099512,0.068309259,-0.04429351,-0.09066616,-0.010880035,-0.017970414,-0.06635611,0.010924963000000001,-0.030128115,-0.140834301,-1.6167315009999998,-2.670954201,0.696998958,1.315006642,-7.092463037000001,-6.544968765,-6.953279297000001,-8.308854576,-6.272642464,-7.382570084,-5.989436282000001,-5.129622228000001,-11.084671974182129,-8.997196197509766,-8.504955291748047,-8.96164608001709,-9.00493049621582 -2244,2244,G142D,-0.037139755,-0.109155751,0.045134795,0.012458292,-2.152682452,0.09106566,-0.08503543599999999,0.010755926,-0.007020396999999999,-0.015571871999999999,-0.20273963,0.066327762,0.023941827000000002,0.03816853,-0.013251946,-1.486625053,-2.818739851,0.48206122100000004,1.311838495,-6.245531575,-5.369806404,-6.866564147999999,-7.200748276000001,-5.248547112,-6.5419919360000005,-5.484147509,-4.88865803,-11.434904098510742,-8.864933967590332,-8.092111587524414,-8.861431121826172,-10.093685150146484 -2245,2245,G142F,-0.082525868,-0.035119733,-0.958413948,-2.472575911,-2.427977434,0.099356751,-0.063602613,-0.101449123,-0.018218296999999998,0.0503695,-0.120608966,-0.9076478640000001,-1.0091800309999999,-2.231796866,-2.713354955,-2.300899835,-2.555055032,1.8065285519999998,0.637570166,-12.24491685,-11.85713472,-12.66633073,-13.2394419,-11.29817021,-12.16350668,-9.35014905,-10.85705337,-15.24811840057373,-15.819005012512207,-13.715234756469727,-12.980263710021973,-13.364105224609375 -2246,2246,G142I,-0.10273421699999999,-0.46508131700000005,-1.611331635,-2.428267757,-2.534184278,0.159800889,-0.091684495,-0.113783939,-0.06743631900000001,-0.096227804,-0.833934829,-1.906422773,-1.316240496,-2.151390529,-2.705144984,-2.220493498,-2.847875058,1.063628505,-0.047296183,-10.93169438,-10.74536913,-11.27484601,-12.045190400000001,-9.954308722999999,-10.63875763,-8.187650882,-7.776074977,-16.157264709472656,-14.193860054016113,-13.644283294677734,-12.974674224853516,-14.697519302368164 -2247,2247,G142H,-0.054401575,-0.059377642,-0.045429303,-0.259108989,-1.944233898,0.11279848599999999,-0.040246866,-0.068556283,-0.018091476999999998,0.000480126,-0.11923541,-0.029728927000000002,-0.061129679000000006,-0.115506175,-0.402711803,-1.938192203,-1.9502755930000002,0.908050571,1.307603874,-10.36928284,-9.757443161,-10.28605537,-11.68717229,-9.28362014,-10.83212322,-8.299737207,-7.776074977,-13.484636306762695,-12.441206932067871,-10.256060600280762,-11.110503196716309,-12.247358322143555 -2248,2248,G142K,-0.03161511,-0.083270858,-0.04902908,-1.341900506,-2.514586481,0.076451929,-0.00779972,-0.055430499,-0.075740482,-0.035235427,-0.13130628800000002,-0.038660747999999995,-0.059397412000000004,-1.094572268,-1.589228743,-2.394124159,-2.635048803,0.83963527,0.7556811040000001,-8.662540465,-8.57718589,-7.853943954,-10.21513865,-7.737710967999999,-8.928722862,-6.729698685,-5.453153235,-10.823213577270508,-11.443380355834961,-9.781557083129883,-9.672167778015137,-9.386550903320312 -2249,2249,G142M,0.005580048000000001,0.054615437999999995,-0.303590933,-2.10269055,-2.631156092,0.043107993,0.005083008,0.006077086999999999,-0.092428006,0.11277675300000001,-0.0035458779999999997,-0.146566145,-0.46061572100000003,-1.438530464,-2.766850636,-2.352731473,-2.90958071,0.8355971879999999,0.7172787420000001,-11.93969234,-11.69991994,-11.79995271,-13.23932696,-10.99054937,-11.9687127,-9.35014905,-10.85705337,-15.217842102050781,-13.475966453552246,-12.415319442749023,-12.811136245727539,-12.854350090026855 -2250,2250,G142L,0.013551728,-0.066283454,-1.275378814,-2.340673341,-3.0035615389999997,0.160271423,0.055107092,-0.028003636000000002,0.001471171,-0.07282936799999999,-0.059737539000000006,-1.1680999859999999,-1.382657641,-2.492248988,-2.189097694,-2.561351957,-3.44577112,0.832023822,0.10881502400000001,-12.05666346,-11.93597468,-11.94419077,-13.28638593,-11.26310127,-11.85366464,-9.35014905,-10.85705337,-14.123518943786621,-13.571468353271484,-11.2382173538208,-12.08863639831543,-12.550166130065918 -2251,2251,G142N,-0.0061224109999999995,0.004108888,-0.01963966,-0.014689238,-1.272083085,0.071778185,0.027970857000000002,-0.040215678,-0.04624702,0.005672825,0.002544951,0.011087225,-0.050366545,0.04403601,-0.073414486,-1.403883996,-1.140282174,0.5555748979999999,1.3170926170000001,-7.799908798,-6.684626297,-8.532624069,-8.882508162999999,-6.834601784,-8.065183678,-6.260274544,-5.728460279,-11.928467750549316,-11.050150871276855,-8.88920783996582,-9.044708251953125,-11.269390106201172 -2252,2252,G142Q,-0.011588764,0.005714159,0.031628617000000005,-1.0193870870000001,-2.542831659,0.096821321,0.003752035,-0.026929562999999997,0.011248873000000001,-0.021372218999999998,0.032800537000000005,0.024130082,0.039127151,-0.424004211,-1.6147699619999998,-2.072890777,-3.0127725410000004,1.5475342330000001,1.347991989,-10.66898906,-10.83950645,-10.11730492,-11.7958629,-9.712838745,-10.879432300000001,-8.451543846,-7.776074977,-12.22185230255127,-11.082198143005371,-9.260778427124023,-9.575804710388184,-9.844108581542969 -2253,2253,G142P,-0.053400637,-0.047392434000000004,-1.203563266,-2.132097089,-3.086825287,0.102056342,-0.0234348,-0.083366473,-0.004681594,-0.033249783,-0.061535085,-0.857623687,-1.549502845,-1.8858823340000002,-2.378311843,-2.8223597380000003,-3.3512908360000004,2.136914817,0.9307250859999999,-9.270669031,-8.431125984,-10.23634682,-10.26241149,-8.062073753,-9.3613871,-7.242511502,-6.68569624,-14.278393745422363,-13.432872772216797,-9.11551570892334,-9.90380573272705,-11.465291976928711 -2254,2254,G142S,-0.038780581,-0.01984802,-0.016873593,-0.009595066999999999,-1.686527285,0.09836341400000001,-0.01963263,-0.057928532000000005,-0.030830386,-0.014612635,-0.025083404,-0.038303451,0.004556266,-0.000848861,-0.018341272,-1.4120018859999999,-1.961052684,0.593721961,1.320521467,-6.15184527,-5.446897148,-6.31739399,-7.264205231,-5.417370002999999,-6.313359977999999,-5.185022817,-4.672779996,-10.276690483093262,-9.401966094970703,-6.7483696937561035,-7.576659679412842,-9.659896850585938 -2255,2255,G142R,-0.042044818,-0.029193134,-0.035561606,-1.491082415,-2.438075268,0.069216978,-0.007940768,-0.076148867,0.011136638,-0.0020858260000000003,-0.056300442,-0.031385962999999996,-0.039737249,-1.252493095,-1.729671734,-2.3768651530000002,-2.499285382,1.008565821,0.762265709,-9.681279542999999,-9.632399742,-9.236397751,-10.874023900000001,-8.477773209,-10.18580311,-7.15470692,-6.5316833039999995,-11.677674293518066,-11.037630081176758,-9.972907066345215,-9.17147159576416,-10.074108123779297 -2256,2256,G142T,-0.08765397,-0.07165683099999999,-0.013367515,-0.074748106,-1.6018280040000001,0.111027755,-0.068567322,-0.10674061800000001,-0.012898788000000001,-0.040050045,-0.103263616,-0.045697176,0.018962147,-0.019823416,-0.129672795,-1.799889505,-1.4037665030000002,0.739051439,1.308293851,-8.102403844,-7.27952729,-8.014841629,-9.354381737,-7.246785407999999,-8.616483153999999,-6.216721832,-4.788835843999999,-11.546411514282227,-11.477591514587402,-8.787038803100586,-9.343412399291992,-10.022090911865234 -2257,2257,G142W,-0.06294942099999999,-0.36454670200000006,-1.7473316000000003,-2.175192098,-2.130593621,0.104795789,-0.016733208,-0.109165634,-0.005952425999999999,-0.047098389000000004,-0.681995015,-1.566934525,-1.927728675,-1.8119022809999998,-2.538481914,-1.881005251,-2.3801819909999997,4.298332589,2.744826203,-11.87994325,-11.26590637,-12.06705408,-13.06177983,-10.99859278,-12.00638319,-9.35014905,-10.85705337,-14.3795166015625,-14.926471710205078,-13.485078811645508,-13.831158638000488,-12.798693656921387 -2258,2258,G142V,-0.006941747,-0.016901748,-1.276927455,-1.645767758,-2.534903025,0.147832321,0.030199741000000002,-0.044083234000000006,-0.062214279000000004,-0.025552091000000002,-0.008251405,-1.234406695,-1.3194482140000001,-1.86934553,-1.422189985,-2.28087118,-2.7889348689999998,3.12628629,1.659614709,-11.27875356,-11.13592869,-11.48950177,-12.25602251,-10.30334683,-11.20896797,-9.00978811,-9.245398002,-14.544456481933594,-12.934133529663086,-12.049773216247559,-11.561501502990723,-12.569134712219238 -2259,2259,G142Y,-0.020395846999999998,-0.002859913,-0.7332440309999999,-1.490110227,-2.7861323689999997,0.164849824,0.021503826,-0.06229552,-0.010708695,-0.005827259,0.000107434,-0.380377832,-1.086110229,-1.470443629,-1.509776824,-2.5395465980000003,-3.032718139,1.6513083780000002,0.892491075,-12.44201434,-12.06116125,-13.11235645,-13.07172317,-11.32951818,-12.63531265,-9.35014905,-10.85705337,-14.81607437133789,-15.109258651733398,-12.641861915588379,-13.449494361877441,-12.867341995239258 -2260,2260,P143A,-0.027449547999999997,0.025518747,-0.017848951000000002,-0.028073294,-1.1555619320000001,0.035648082000000005,-0.005749587,-0.049149508,-0.0059857669999999995,-0.000451576,0.05148907,-0.003798981,-0.031898921000000004,-0.033611351,-0.022535237000000003,-1.146633414,-1.164490449,0.6661265989999999,1.339838995,-6.53739415,-6.038025833,-8.748475716,-6.50633815,-5.332448563,-6.061682487000001,-6.365702676000001,-2.40374905,-9.060436248779297,-10.098970413208008,-7.812948226928711,-10.869123458862305,-10.892987251281738 -2261,2261,P143C,-0.059361146,0.008437733000000001,-0.00646229,-0.019434292,-1.774256601,0.036847143,-0.048344839,-0.07037745200000001,0.012166999,-0.017189342,0.034064807,0.032404517,-0.045329096,0.003022429,-0.041891012000000005,-1.374011993,-2.174501208,0.6859922909999999,1.327010499,-12.01055073,-12.29039792,-14.56644402,-11.07285207,-10.6918622,-11.43119746,-10.06511847,-6.849734047,-13.81007194519043,-15.575485229492188,-12.24526309967041,-15.378369331359863,-14.26162338256836 -2262,2262,P143E,-0.040004756,0.025175263,-0.046077083,-0.579766279,-2.245986947,0.040978127,0.009048587,-0.089058098,0.065299361,0.007843421,0.042507105,-0.027322772999999998,-0.064831392,-0.219952896,-0.9395796609999999,-1.941145341,-2.550828553,1.24732889,1.33097985,-11.12599111,-10.798226699999999,-13.49302814,-10.3230258,-9.620823913999999,-11.39485101,-8.386506725,-3.99851794,-12.572460174560547,-13.639073371887207,-10.508317947387695,-13.703567504882812,-15.352601051330566 -2263,2263,P143D,-0.060209362999999995,0.047597100999999996,-0.325704275,-1.95852858,-2.9881581539999997,0.006362817,-0.066033185,-0.05438554,-0.059639375,0.033937607,0.061256595,-0.164084507,-0.487324042,-1.496003241,-2.421053919,-2.77687708,-3.199439228,1.264451243,0.775584791,-12.65392538,-12.60947099,-15.71249095,-11.88202493,-10.35736584,-12.70827422,-9.123094562999999,-4.671164283,-13.756927490234375,-14.214988708496094,-12.347456932067871,-14.934356689453125,-16.603153228759766 -2264,2264,P143G,-0.00139505,0.050165626,-0.019464478,-0.035218314,-1.833277047,0.003680445,0.015694003,-0.018484102,-0.042035486,0.0048618279999999995,0.09546942300000001,-0.034042914,-0.004886041,0.0017824170000000001,-0.07221904400000001,-1.6107983540000002,-2.055755739,0.6504015360000001,1.312397861,-9.519024211,-8.963970726,-12.34241113,-8.479893959,-9.463693588,-8.345151649,-7.6389238420000005,-2.9153602910000003,-11.965874671936035,-13.263686180114746,-10.977760314941406,-14.84278392791748,-14.48039722442627 -2265,2265,P143F,-0.049734357,0.015532533000000001,-0.037831506,-0.930476462,-2.387195776,0.017569422,-0.024534082000000002,-0.074934632,-0.093080096,-0.019773844,0.050838909,-0.00042062400000000003,-0.07524238700000001,-0.35761594799999996,-1.503336976,-2.075843915,-2.698547637,1.551706052,1.345293151,-12.0926022,-15.07377172,-14.89256205,-9.611927055,-9.659302109,-11.22544806,-8.343966882,-3.131284202,-11.746565818786621,-14.77941608428955,-12.20058822631836,-15.482500076293945,-14.274985313415527 -2266,2266,P143I,-0.12472323699999999,0.022631218999999998,-0.06551781,-0.22808325699999998,-2.005215035,-0.009572492,-0.063933646,-0.185512827,-0.061946442000000004,0.043551648,0.0017107889999999999,0.001122164,-0.132157783,-0.088948189,-0.367218324,-1.822119698,-2.1883103719999997,0.961765723,1.318747064,-8.517390579,-10.08056106,-11.37134324,-7.456979057000001,-5.98103772,-7.6970318220000005,-5.676446916000001,-2.20098652,-12.928800582885742,-13.811151504516602,-11.331653594970703,-14.479280471801758,-12.982641220092773 -2267,2267,P143H,-0.01400415,-0.060021736,-0.065957663,-0.063149184,-0.6523088920000001,-0.012056058,-0.022413492,-0.005594808000000001,-0.013609597,-0.025324008999999998,-0.09471946199999999,-0.058919333,-0.072995992,-0.039095221,-0.087203147,-0.579309619,-0.725308165,1.234363111,1.6253157630000001,-13.04623011,-13.368855199999999,-16.07421033,-10.91184659,-11.04256599,-13.83367247,-9.074199408,-5.571040707000001,-13.200538635253906,-12.857272148132324,-10.751511573791504,-13.817264556884766,-14.469010353088379 -2268,2268,P143K,-0.023671493,-0.011107724,-0.09688148,-1.622279905,-2.718579118,0.048967530999999995,0.034438626,-0.08178161099999999,0.023904781,-0.09372256300000001,0.071507115,-0.09016361099999999,-0.10359934800000001,-1.401993487,-1.8425663230000002,-2.162994091,-3.274164145,1.012579794,0.7463549820000001,-11.46886972,-12.29676807,-14.53057054,-9.349727698999999,-9.556155525,-11.61112675,-7.934823852,-3.162355406,-13.432344436645508,-14.828413009643555,-11.445032119750977,-15.234576225280762,-15.349388122558594 -2269,2269,P143M,-0.028300197000000003,0.019771131,0.028614413999999998,-0.865263771,-2.50650652,-0.051351500999999994,0.041746234,-0.09834662699999999,-0.136148448,-0.017261789,0.05680405,0.012467398000000001,0.04476143,-0.500198509,-1.230329032,-2.24673398,-2.76627906,1.6812704680000001,1.345340835,-10.91956935,-12.4040781,-13.57858528,-9.827217285,-9.860710327,-8.92725576,-8.005466323,-2.086890233,-11.745288848876953,-14.070014953613281,-11.451558113098145,-14.51834774017334,-13.84648609161377 -2270,2270,P143L,-0.069901857,0.016946881,-0.019754515,-0.973330075,-1.965140669,0.032872637,-0.040426506,-0.099377207,-0.001331792,0.012080200000000001,0.021813562,0.000767597,-0.040276626,-0.459567137,-1.4870930130000002,-1.5450654730000002,-2.385215864,1.835056517,1.561962605,-8.978137535,-11.87773618,-10.60471458,-7.919180016,-6.610610877999999,-7.87844603,-7.157352134,-1.754621274,-10.728028297424316,-12.249861717224121,-10.164345741271973,-11.932762145996094,-11.506692886352539 -2271,2271,P143N,-0.047994887,0.022793876,-0.02139908,-0.757630274,-1.942733992,0.029940152,-0.029506526,-0.066483248,-0.054393304,0.006904405,0.038683347,-0.026017367000000003,-0.016780792,-0.288605328,-1.22665522,-1.9420843559999998,-1.9433836269999998,1.33580458,1.341437604,-12.22861652,-12.28358269,-15.29183935,-11.12916464,-10.50826353,-11.93023238,-9.513602443,-5.964658021,-13.6854248046875,-14.096451759338379,-11.381083488464355,-14.675612449645996,-15.115490913391113 -2272,2272,P143Q,-0.033764503,0.067979289,0.012350669,0.012693448000000001,-1.2699222540000001,0.02447694,0.028745075,-0.096274081,-0.051621792,0.053803524000000005,0.08215505299999999,0.049616892999999995,-0.024915556000000002,0.086557229,-0.061170333,-1.119379945,-1.4204645619999998,0.453999266,1.3242181259999999,-11.51428711,-12.45492176,-13.73444318,-10.09584335,-9.589359459,-11.69686783,-8.094200721,-4.14833374,-11.993077278137207,-12.394335746765137,-9.90815544128418,-12.734432220458984,-12.402647018432617 -2273,2273,P143S,-0.054796433,0.001417655,-0.014364027,-0.021803705,-1.6966460890000001,0.009052072,-0.03571065,-0.073882215,-0.025774752,0.018070564,-0.015235253999999998,-0.004460602,-0.024267451000000002,0.036599037,-0.080206446,-1.6109571169999999,-1.782335061,0.514476698,1.306907684,-7.742215562,-6.923545562999999,-9.644116713999999,-7.500043251,-6.9928632660000005,-7.650509017999999,-7.631680547999999,-4.7312467730000005,-10.282894134521484,-10.930129051208496,-8.704290390014648,-11.50220012664795,-11.02337646484375 -2274,2274,P143R,-0.04389502,0.01665216,-0.15671147300000002,-1.443419754,-2.376351269,0.072213813,-0.010187705,-0.07760233400000001,-0.021634924,-0.044471102,0.077775422,-0.08832319699999999,-0.225099749,-1.280221379,-1.606618128,-1.7761045430000002,-2.9765979939999996,3.573738718,2.7135467610000004,-10.99257254,-12.00351657,-13.73030212,-8.860979362,-8.760707184,-11.60735744,-7.628152817999999,-3.512597695,-13.681865692138672,-13.567168235778809,-10.656550407409668,-13.939132690429688,-13.888955116271973 -2275,2275,P143T,-0.017624823,0.057412229,0.010783477,0.001014245,-1.151452176,0.06747499400000001,0.010002722,-0.045252367,0.00367954,0.066514693,0.048309764000000005,0.043518243,-0.021951289,0.052567164000000006,-0.050538675,-1.020670119,-1.282234232,0.581681915,1.340959376,-6.191726691,-6.04389904,-8.428460068,-5.909918976,-4.912681175,-5.6636741939999995,-6.507101136,-2.31663867,-10.228189468383789,-10.774045944213867,-8.832414627075195,-10.634034156799316,-10.747474670410156 -2276,2276,P143W,-0.0006648139999999999,0.045913962999999995,-0.613228645,-2.109361463,-3.021949433,0.033801728999999996,0.069815221,-0.071144848,0.011684896,-0.034468899,0.126296824,-0.307006702,-0.919450587,-1.477685999,-2.741036926,-2.7005678910000004,-3.343330975,1.5436015269999999,0.850944875,-12.94510947,-12.75166636,-16.18462139,-11.21995959,-11.28570535,-13.28359467,-9.033611025,-5.269048819,-15.56442928314209,-15.746978759765625,-14.33850383758545,-17.253803253173828,-17.646072387695312 -2277,2277,P143V,-0.013427063999999999,0.047426811,-0.025616377000000003,-0.041868353,-1.539005603,0.025029682999999997,0.015545993999999999,-0.042400121,-0.022800205,-0.000169072,0.095022694,-0.033473897,-0.017758857,-0.038131522,-0.045605183,-1.560934099,-1.517077106,0.9227773000000001,1.334189947,-7.760243381,-8.611276825,-10.87627431,-6.51744294,-5.406311516000001,-7.389911316,-5.808696795,-2.55664857,-11.43610668182373,-12.506675720214844,-10.074579238891602,-13.166712760925293,-12.001460075378418 -2278,2278,P143Y,-0.083510742,0.037057951,-0.071059861,-2.117514864,-2.758068812,0.0720154,-0.06142178400000001,-0.105599699,-0.018278327,0.008108923,0.066006978,-0.04153321,-0.10058651199999999,-1.486991221,-2.7480385060000003,-2.165805068,-3.350332555,1.075878807,0.7328546109999999,-12.89427005,-14.68626721,-16.16381075,-9.996887955,-10.09441668,-13.52996767,-7.762556547000001,-4.307385026,-14.371349334716797,-13.357728958129883,-12.823436737060547,-15.445873260498047,-15.488245010375977 -2279,2279,K144A,-0.006117771,-0.080593749,0.002331417,-0.009388397,-0.072388927,0.048290677000000004,0.01476768,-0.027003221,0.010292264,-0.079850648,-0.08133685,-0.040938787000000004,0.045601620999999995,-0.027326684,0.00854989,-0.062482442,-0.082295411,1.356455985,2.37120265,0.302930457,0.275363205,-0.39577549,0.77296669,0.512806564,0.349291313,-2.209876447,0.9549755320000001,-1.9528753757476807,-2.11181640625,-3.0600056648254395,-2.2021965980529785,-4.960282802581787 -2280,2280,K144C,-0.045242494,-0.068711581,-0.01396067,-0.033098357,-0.17192907899999998,0.105578579,7.77e-05,-0.090562688,-0.012907638,-0.072455965,-0.064967197,-0.022636732000000003,-0.005284606999999999,0.0030154820000000003,-0.069212195,-0.145069305,-0.198788852,1.250716872,2.12455322,-5.7679525279999995,-5.110060425,-6.708175957000001,-5.978851822,-5.5273623810000005,-5.515312057999999,-7.908438113,-5.478130544,-9.324703216552734,-8.552642822265625,-10.17799186706543,-10.391470909118652,-11.340690612792969 -2281,2281,K144E,0.001336261,-0.025060048999999997,-0.002331254,-0.015830223,-0.022203867000000002,0.003069423,0.041253265,-0.038580744,-0.016028753,-0.057707469000000004,0.007587371,-0.019412481000000002,0.014749973999999999,-0.007947353,-0.023713092999999998,-0.058864047,0.014456313,1.3962876,2.5036407000000005,0.6334934489999999,0.385567764,0.397957436,1.121579803,0.950045395,0.312316849,-2.600582312,0.870753971,-3.61027455329895,-2.3472442626953125,-4.011780261993408,-2.928272247314453,-6.587137222290039 -2282,2282,K144D,-0.076503938,-0.08135228900000001,-0.013722558999999999,-0.064692552,-0.055729847,0.092765002,-0.02683749,-0.126170386,0.004756833,-0.110774891,-0.051929687,-0.06430178,0.036856663,-0.024633686000000002,-0.104751417,-0.09238693699999999,-0.019072757,1.36285572,2.2951806809999997,-1.837801918,-1.7914201969999999,-3.1419546130000002,-0.318335037,-2.514191109,-1.423108635,-4.601068156,0.722602588,-4.21940803527832,-4.2947998046875,-5.12916898727417,-3.988577365875244,-7.6556878089904785 -2283,2283,K144G,-0.016011456,-0.042885912000000005,-0.006566879,-0.017222104,-0.020137481999999998,0.023783593,-0.003259748,-0.028763162999999998,0.013208295,-0.070958004,-0.01481382,-0.046260129000000004,0.033126371,-0.018489068,-0.015955139,-0.04639569,0.006120726999999999,1.31870905,2.431119397,-2.5649941640000002,-2.284029167,-4.277086945,-1.9139443740000002,-2.125563316,-2.224347015,-4.411702013,-0.527993782,-4.7749152183532715,-4.916452407836914,-4.677445411682129,-4.5595011711120605,-6.933247089385986 -2284,2284,K144F,0.048200585,0.009135824,0.042906682,-0.00583436,-0.074061544,0.014287563999999999,0.057242352999999996,0.039158816,0.079987625,-0.038672889,0.056944536,-0.054156317999999995,0.13996968199999998,-0.04219065,0.030521931000000002,-0.098231745,-0.049891343,1.372849976,2.309139269,-5.085984941,-3.649625038,-6.715675591,-5.442262283,-4.9485835719999995,-4.673778221,-6.913211511,-4.194719319,-8.592062950134277,-7.847963333129883,-8.34429931640625,-8.699844360351562,-11.185705184936523 -2285,2285,K144I,-0.014477304,0.003957895,-0.0095023,0.065604517,0.047126188,-0.025531257999999998,0.015414862,-0.044369469,-0.052958175,0.040586383,-0.032670594,0.031405969,-0.050410569,0.147072839,-0.015863806,0.001833794,0.092418581,1.137271404,2.68373177,-3.847411601,-2.0893127369999998,-4.874347984,-3.8967623139999996,-4.432372147,-3.944262825,-6.4166599479999995,-3.406380153,-6.549757957458496,-5.952082633972168,-6.755801677703857,-6.7295026779174805,-8.35498046875 -2286,2286,K144H,-0.031426317999999995,-0.007453538000000001,0.048767436,0.031028704,-0.009511754,0.09816811199999999,0.019629486,-0.08248212099999999,-0.032233212000000004,0.034617614,-0.04952469,0.04702390099999999,0.05051097,0.048289639,0.013767769,0.023878148999999998,-0.042901655999999996,1.124699656,2.582810921,-3.2945932389999997,-2.369472504,-4.827764923,-3.2566109310000004,-2.966116379,-3.0530014569999997,-4.91540279,-2.635765889,-6.060368537902832,-4.961798667907715,-5.913675308227539,-5.508946418762207,-6.37205696105957 -2287,2287,K144M,-0.030677691,-0.052012224,-0.036494797999999995,-0.046657784,-0.076435888,0.033177188999999996,0.009756144,-0.071111525,-0.000786915,-0.101875003,-0.002149445,-0.100676494,0.027686897999999998,-0.06416028900000001,-0.029155279,-0.121309766,-0.031562009,1.494608538,2.298426105,-3.756495451,-2.791544212,-4.906698021,-3.52389724,-4.072224609,-3.488113174,-5.781763947999999,-3.579595325,-7.216869831085205,-6.264302730560303,-6.5126495361328125,-7.256350517272949,-8.744072914123535 -2288,2288,K144L,-0.028383135,-0.068444093,-0.014159005,-0.023360785,-0.083766349,0.032343275,-0.005900178000000001,-0.050866090999999995,0.027364957999999998,-0.051738965,-0.085149221,-0.023832264,-0.004485745,-0.002449079,-0.044272491,-0.075705196,-0.09182750099999999,1.351470762,2.3553165430000003,-3.180989313,-2.005607544,-4.206407318,-3.396513557,-3.3365633619999997,-2.959854782,-5.4632451060000005,-2.810241832,-6.207070350646973,-5.831576347351074,-5.9844441413879395,-6.296065330505371,-8.346532821655273 -2289,2289,K144N,-0.030653457999999998,-0.019735421,0.019137653,-0.018144852,-0.004878996,0.036265724,-0.009139058,-0.052167858,0.025501781,-0.009102675,-0.030368166000000002,-0.002556184,0.04083149,0.007129481,-0.043419184000000006,0.033103296000000004,-0.042861287000000005,1.146717002,2.694846918,-2.6895999710000003,-2.497229416,-3.908333771,-2.2670781019999997,-2.420422813,-2.354935753,-4.6225795,-1.253847636,-5.063977241516113,-5.068450927734375,-5.776330947875977,-5.021435260772705,-6.748906135559082 -2290,2290,K144Q,-0.015007248,-0.044765932,0.006803765,0.0034771309999999996,-0.012246845,0.057304697,0.011979674,-0.04199417,0.080263362,-0.069327262,-0.020204602,-0.000288323,0.013895853,-0.037923441,0.044877703,-0.033730776000000004,0.009237086,1.277769363,2.4540059640000003,1.1941698790000002,1.315619934,1.224047997,1.108029457,1.537407219,0.7857447890000001,-2.057751389,-0.10223279099999999,-3.9783575534820557,-2.4906506538391113,-3.5113401412963867,-3.3585712909698486,-4.545624256134033 -2291,2291,K144P,-0.056837282,-0.103395044,-0.021428383,-0.039765344,-0.127841549,0.08336550200000001,-0.035530576,-0.078143987,0.012711667,-0.06302067900000001,-0.14376940900000001,-0.051519502,0.008662737,-0.022853326,-0.056677360999999996,-0.10377577,-0.15190732699999998,1.502683455,2.427753997,-1.937269453,-1.436102142,-3.0228598860000004,-1.289556236,-2.156744995,-1.7810840069999998,-3.631408579,-0.510029683,-3.5989344120025635,-3.8042120933532715,-5.628665924072266,-3.711418628692627,-6.9875993728637695 -2292,2292,K144S,-0.049289785,-0.08164013,0.011166371999999999,-0.025468378,-0.054032555999999995,0.064306298,-0.013642208999999999,-0.08493736,0.013471641999999999,-0.060438320999999996,-0.10284193800000001,-0.009987288,0.032320032,-0.021798819,-0.029137936,-0.043647131,-0.06441798,1.299251671,2.391722178,-0.382830165,-0.408854431,-0.339947189,-0.557738159,0.0007668760000000001,-0.6083779220000001,-2.560178641,-0.358870387,-3.8718440532684326,-3.585136890411377,-4.322103977203369,-4.113536357879639,-6.202060699462891 -2293,2293,K144R,-0.057966532,-0.112444244,-0.010584129,-0.035538135,-0.08119536299999999,0.055999597000000005,-0.038576068,-0.077356995,0.00011535899999999999,-0.091841547,-0.133046941,-0.052569125,0.031400868,-0.026521241,-0.044555029,-0.061275555,-0.10111517,1.200807553,2.262246452,-1.984859116,-1.5662122040000002,-3.576941986,-1.5741716540000001,-1.5692630840000001,-1.63770665,-4.540416486,-1.07919313,-4.97874116897583,-4.574377059936523,-4.625480651855469,-4.837797164916992,-4.472781658172607 -2294,2294,K144T,-0.031893651,-0.078255985,0.018076231,-0.034641512,-0.074526532,0.045888701,-0.0031472740000000003,-0.060640027,0.005554747,-0.039030326000000004,-0.11748164300000001,0.010727647,0.025424814,0.011412463000000001,-0.080695486,-0.022870337,-0.126182727,1.266983826,2.5937999080000003,-1.595598286,-1.0801063,-1.929799835,-1.068138802,-2.1464048,-1.753541695,-3.531766616,-0.593603585,-4.117636680603027,-3.1158645153045654,-4.502256393432617,-3.876317024230957,-5.8462677001953125 -2295,2295,K144W,-0.017560163,-0.05158539,0.019913603000000002,-0.002688137,-0.261537109,0.067386068,0.035637531,-0.070757856,0.051007998,-0.071731501,-0.031439279,-0.025920223,0.065747428,0.007343121,-0.012719395,-0.24025080899999998,-0.282823408,1.28184705,1.934994197,-6.73066387,-5.641495476,-8.407188049,-6.820401855,-6.437429665,-6.346804306,-8.812428334,-7.8557801110000005,-10.296258926391602,-10.409269332885742,-10.40921401977539,-10.035665512084961,-11.534379959106445 -2296,2296,K144V,0.034359195,-0.024476558,0.004586651,-0.016167922,-0.046394863,-0.004641254,0.05299052,0.01572787,0.057371519,-0.065426236,0.01647312,-0.040672076,0.049845377999999996,-0.029807822999999997,-0.00252802,-0.10147134,0.008681615,1.237718668,2.1920717869999997,-2.539870451,-1.3944380719999998,-3.4182008739999996,-2.235449615,-2.862221313,-2.7890423810000002,-4.97990092,-2.456621448,-5.0565290451049805,-4.4166131019592285,-5.444473743438721,-5.016058444976807,-7.035632133483887 -2297,2297,K144Y,-0.048801954,-0.065310692,0.012981718,-0.084173709,-0.17401648399999997,0.074583821,-0.016132627,-0.08147128,0.014396316999999999,-0.065327515,-0.065293868,-0.053411956,0.079375392,-0.06588665099999999,-0.102460767,-0.126025356,-0.222007612,1.528177275,2.337570839,-5.643091803,-3.905824646,-7.693876381,-5.947505211,-5.3702015229999995,-5.298051254,-7.23729785,-4.716147851000001,-8.864858627319336,-7.5345964431762695,-8.318408012390137,-8.178415298461914,-10.264759063720703 -2298,2298,E145A,0.022845756000000002,0.00631522,-0.014641312,-0.021954262999999998,-0.027764072999999997,-0.072845512,0.00301391,0.042677602,0.011867588,0.004105509,0.008524931,-0.056584034000000005,0.02730141,-0.032374579,-0.011533946000000002,-0.041875897999999995,-0.013652248,1.468686135,2.631213339,1.7433922419999999,1.2191588290000002,1.93155175,2.178545311,0.803248238,2.584457085,-1.793517546,1.799167409,-2.906132221221924,-3.2344822883605957,-2.6067771911621094,-1.0714530944824219,-3.0739259719848633 -2299,2299,E145C,0.043467187000000004,0.082231826,0.018240006,0.019472262,-0.054622107,-0.027692176000000002,0.037572702,0.049361670999999996,-0.03699381,0.118358578,0.046105072999999996,-0.017136698,0.053616709000000005,0.014530995,0.024413529,-0.092053977,-0.017190236,1.416405485,2.403274077,-5.778317261000001,-6.809432465,-5.853200622999999,-5.216282837,-6.457572272999999,-4.555098106,-7.688842471,-3.908355492,-10.045966148376465,-10.209817886352539,-10.396955490112305,-8.368731498718262,-9.927507400512695 -2300,2300,E145D,-0.011863651999999999,0.030829767999999997,0.023021358,-0.032399874,-0.053888557999999996,-0.011271006,-0.031593849,0.007866546,-0.146170616,0.00697162,0.054687915,0.038113804,0.007928912,-0.004163785,-0.060635963,-0.08184361700000001,-0.025933498,1.250022999,2.3243472769999998,-3.3299683030000002,-3.5169245910000004,-4.392891373,-2.730646118,-3.527546135,-2.481833298,-5.350867019,-1.552260371,-5.951236724853516,-4.898903846740723,-5.032923698425293,-5.033520698547363,-5.1207146644592285 -2301,2301,E145G,0.000818953,0.031151365,0.018635137,0.013202008000000001,-0.009259429,-0.10308789199999999,-0.01312609,0.014763995,0.025350836,0.035416637,0.026886093,0.008385102,0.028885171,0.005678826999999999,0.020725188000000002,-0.02882837,0.010309512,1.3185494009999998,2.548144504,2.634117546,2.34168972,2.476275658,3.3534856719999997,2.0925282590000003,2.906608421,-1.5561279959999998,1.154514236,-1.3202075958251953,-1.699758529663086,-1.931891918182373,1.1286802291870117,-1.1603493690490723 -2302,2302,E145F,0.03877373,0.069160796,0.019534863,0.036830788999999996,-0.010103721,-0.06150710400000001,0.014220781000000002,0.063326679,0.022808292,0.052346915,0.085974677,-0.02398782,0.06305754599999999,0.020663625,0.052997952,-0.072582235,0.052374794,1.312338293,2.412514195,-5.493358242999999,-6.379035995,-5.167361389,-4.520440445,-6.93263578,-4.467317604,-6.845080586,-2.246614135,-9.363429069519043,-9.44295597076416,-9.484810829162598,-8.986858367919922,-10.142539978027344 -2303,2303,E145I,0.021632242000000003,0.034570276000000004,-0.016591138000000002,0.011127513,-0.19679012899999998,0.038924162000000005,0.070113745,-0.026849262000000002,-0.148262165,-0.025634284,0.094774836,-0.07669793700000001,0.043515661,-0.019205137,0.041460162,-0.193206143,-0.200374114,1.2020937809999999,1.946879852,-4.712768831,-5.146645027,-4.633297913,-4.058873802,-5.5728279039999995,-4.152199509,-7.144536454,-2.4096818669999998,-8.68254280090332,-8.118267059326172,-9.01030445098877,-8.386239051818848,-9.182623863220215 -2304,2304,E145H,-0.081839461,-0.015559261999999999,-0.012826337,-0.0243495,-0.07193353799999999,-0.04285923,-0.110413045,-0.053265877,-0.03775049,0.027355769,-0.058474293,0.017281234,-0.042933908,-0.005250541,-0.043448457999999995,-0.031907606,-0.11195947,1.297238333,2.549696033,-5.29394483,-6.477287673999999,-4.7818944089999995,-5.255828835,-4.9160555189999995,-5.038657715,-6.108466924,-1.841764068,-6.304447650909424,-7.2565999031066895,-7.183089256286621,-6.309444427490234,-7.052424907684326 -2305,2305,E145K,-0.076558844,0.005615403000000001,0.024360251,0.032623615,-0.034367585,-0.045516645999999994,-0.07469349900000001,-0.07842418799999999,-0.077175263,0.147030106,-0.13579929999999998,0.090773337,-0.042052835999999996,0.048846525999999994,0.016400703,-0.0034291309999999998,-0.06530603900000001,1.361033919,2.7995177910000004,-0.338064066,0.078408905,-0.669888405,-0.762160133,-0.153487297,-0.183193398,-3.028864711,0.12419799699999999,-5.3333024978637695,-6.248522758483887,-5.865021705627441,-5.068499565124512,-5.735968589782715 -2306,2306,E145M,0.032224465,0.015993195,0.046906279,-0.0054855680000000006,0.002160508,-0.008474213000000001,0.024539803,0.039909126,-0.05597384,0.012988382,0.018998008,-0.012795048,0.106607606,0.01731673,-0.028287865,-0.026224172999999996,0.030545187999999997,1.190436872,2.4920165659999998,-4.606095792,-5.389888954,-4.216062058,-4.325534248,-4.827102936,-4.271890762,-6.428849548,-2.8747289510000003,-7.371490478515625,-7.859640121459961,-8.027301788330078,-8.110285758972168,-8.648643493652344 -2307,2307,E145L,-0.017335511,0.006945560999999999,0.000790482,-0.021533885,-0.185923179,-0.07039387,-0.029855599,-0.004815422,-0.024955127,0.032140685,-0.018249563,-0.014012877,0.01559384,0.005627558,-0.048695327999999996,-0.148991867,-0.22285449100000002,1.493747231,2.3264306169999998,-4.650396411,-5.269429222,-4.976234077,-4.58054007,-4.460128212,-3.965650475,-6.532051257000001,-2.52470143,-7.236776828765869,-7.75595760345459,-8.013324737548828,-7.9170122146606445,-8.910820960998535 -2308,2308,E145N,-0.056568785999999996,-0.009446366999999999,0.015387708,-0.02253726,-0.082234238,-0.034583653,-0.10502145800000001,-0.008116114,-0.05015271599999999,0.015861247,-0.034753981,0.02740289,0.003372525,-0.042587997999999995,-0.0024865210000000002,-0.053768946,-0.11069953,1.272643205,2.332220377,-2.90443363,-3.57780265,-3.186611473,-3.0464258039999996,-2.825981415,-1.885346809,-6.157731432,0.23478760899999998,-5.05180549621582,-6.228481769561768,-5.172469139099121,-4.8765716552734375,-5.360595703125 -2309,2309,E145Q,0.014477441,0.022088366,0.047769373,0.028610389,-0.051717017000000004,-0.100241434,-0.03239694,0.061351822,0.009325957,0.016754201,0.027422531,-0.004083413,0.099622159,-0.009399914,0.066620692,-0.044963812,-0.058470220999999996,1.270198658,2.429479188,-0.98067986,-0.946041107,-1.281467972,-1.17690081,-0.380323746,-1.118665665,-4.348638757,-0.660509924,-5.046249866485596,-4.892930030822754,-4.747176170349121,-4.478204727172852,-4.827169895172119 -2310,2310,E145P,-0.015483133999999999,0.028818318,0.001621454,-0.026806884,-0.36504550799999996,-0.017538035,-0.040944601000000004,0.009978333,-0.002220481,0.026975582999999997,0.030661052999999997,-0.025761432,0.02900434,-0.006848993,-0.046764775,-0.291053381,-0.439037635,1.019048146,1.703051022,-3.6338646910000003,-4.9160649030000005,-3.2990614239999996,-3.2222005080000002,-4.196377411,-2.535619209,-6.203360854,-1.76662898,-6.628431797027588,-6.089247703552246,-6.337394714355469,-5.531469345092773,-6.875221252441406 -2311,2311,E145S,0.015603816999999999,0.009995098000000001,0.020813252,-0.007909723,-0.019853986,-0.072531346,0.002118512,0.029089121000000003,-0.02810294,0.052861026,-0.032870831,0.005595475,0.036031029,-0.022708867,0.006889421999999999,-0.018305093,-0.021402877999999997,1.489016835,2.794626567,-0.742267497,-1.805109505,-0.244460335,-0.446374527,-0.928086327,-0.287306793,-4.218926581,-0.310399684,-5.543460845947266,-4.901016712188721,-4.627058029174805,-2.882662057876587,-4.609879970550537 -2312,2312,E145R,0.0076392790000000006,-0.008101718,0.025245251,0.015498078,-0.086826265,-0.055318108,-0.007191362,0.022469918999999998,0.002341216,0.049697989000000005,-0.065901424,0.014269956,0.036220545,0.007358027,0.023638129,-0.058703062,-0.11494946800000001,1.1596874259999999,2.3158833480000003,-2.366750713,-3.176674179,-2.7129398960000004,-2.146143425,-2.013504623,-1.78449144,-5.172789439,0.14726409099999999,-6.463352680206299,-7.076948642730713,-6.938434600830078,-5.207335472106934,-5.943702220916748 -2313,2313,E145T,-0.014741609,0.00017491299999999998,-0.02332578,-0.015505611,-0.100024051,-0.07175675,-0.061533878,0.032050661,-0.011991799999999999,0.024140832999999997,-0.023791007000000003,-0.005827771999999999,-0.040823787,-0.014919923,-0.016091299,-0.10348081099999999,-0.096567291,1.39301399,2.288843354,-2.057515475,-2.9677396239999996,-1.34069529,-1.935306236,-2.4962191540000003,-1.547617073,-5.2973734619999995,-0.152210339,-6.2275800704956055,-5.215714931488037,-5.558886528015137,-4.548186302185059,-6.00294828414917 -2314,2314,E145W,-0.012279911999999999,-0.002168963,0.031635458,-0.010807998999999999,-0.182909331,-0.048243590999999995,-0.00414354,-0.020416284,-0.00011206200000000001,0.052168492000000004,-0.056506417999999996,0.03562338,0.027647536,0.028229485,-0.049845482999999996,-0.124774015,-0.241044646,1.306080109,2.198350787,-7.723893787000001,-8.40468222,-7.670265808,-7.175258827,-8.348087036,-7.021175041,-8.733595714,-5.269939067,-9.844614028930664,-9.737787246704102,-10.441046714782715,-9.009209632873535,-10.281647682189941 -2315,2315,E145V,0.002117856,-0.001501229,-0.015994641,-0.017126544,-0.058114107000000005,-0.052030869,-0.022976708,0.027212418999999998,0.024123672999999998,-0.033175846,0.030173389,-0.065256655,0.033267374,-0.042400874000000005,0.008147787,-0.09699526800000001,-0.019232946,1.4510355940000002,2.370000038,-1.5085273240000001,-1.736321571,-1.4593324280000002,-1.1876507109999999,-2.3278465809999997,-0.831485329,-4.4809437569999995,-0.291165862,-6.851268768310547,-6.549621105194092,-6.814090251922607,-5.666638374328613,-7.044406414031982 -2316,2316,E145Y,0.039136678,0.021443648,0.039206543999999996,-0.026655111000000002,-0.131728189,-0.09873917900000001,0.005006806,0.073266549,0.106351569,0.030952313,0.011934982,-0.03033284,0.10874592699999999,-0.036317047000000005,-0.016993174,-0.085792674,-0.177663703,1.343824961,2.330025806,-5.598873189,-6.617844657999999,-4.936351341,-5.11924324,-6.29916478,-5.021761925,-6.268809473999999,-1.20131469,-7.784425735473633,-8.74416732788086,-8.592279434204102,-7.832231521606445,-9.359607696533203 -2317,2317,L146A,-0.034015684,-0.012178268,-0.039606414,0.024280585,-1.532918971,0.07624879,-0.056910185999999995,-0.011121181,0.07147878099999999,-0.020740384,-0.0036161509999999997,-0.036997463,-0.042215365,0.0315296,0.01703157,-1.528424464,-1.5374134769999999,0.6027035070000001,1.314318895,-9.285173624,-9.940624847,-13.44735566,-5.978938667,-8.092017906,-8.966931038,-6.768816994,-2.8885825639999996,-8.748576164245605,-11.044441223144531,-9.795490264892578,-10.145381927490234,-10.036043167114258 -2318,2318,L146C,-0.09579998699999999,-0.000362203,-0.053614489,-0.434164286,-1.6835959569999999,0.086013509,-0.152356841,-0.039243133,0.091061999,0.041149826,-0.041874232000000004,0.015905065,-0.123134042,-0.068192134,-0.800136437,-1.726291024,-1.64090089,0.717562409,1.310414273,-10.21868455,-11.03765356,-13.80048784,-7.70036515,-9.09180471,-9.463111465,-8.110734371,-5.282824853,-10.332376480102539,-11.424908638000488,-11.7623291015625,-12.173097610473633,-12.414262771606445 -2319,2319,L146E,-0.016862116,-0.165975894,-1.21986184,-2.3340640269999997,-2.67514971,0.012750069,-0.02464744,-0.009076792,0.086920451,0.044328799,-0.37628058700000006,-1.078448789,-1.3612748909999999,-2.012900152,-2.655227901,-2.565230885,-2.785068535,2.241326417,0.91437846,-12.8766624,-13.52648541,-16.29816574,-10.14197507,-11.78549281,-12.63119297,-10.12035764,-9.384185772999999,-12.492324829101562,-14.627425193786621,-11.642190933227539,-14.014214515686035,-14.79356861114502 -2320,2320,L146D,0.025355035,-1.397950819,-1.6952170030000002,-2.059260921,-2.8228956239999996,0.019997473,0.029049421000000002,0.021660647999999998,-0.006950625,-1.277565505,-1.518336133,-2.007476018,-1.382957987,-2.529746933,-1.5887749080000002,-2.604956411,-3.040834837,0.344411359,-0.761082742,-13.40042178,-13.91537703,-17.46630545,-10.44640417,-12.12943458,-13.04458768,-10.12035764,-9.384185772999999,-14.737208366394043,-17.030227661132812,-15.570820808410645,-16.483428955078125,-17.691219329833984 -2321,2321,L146G,-0.058312487,-0.025574837000000003,-0.051067283,-1.5283667419999998,-2.258073028,0.033572789,-0.067787681,-0.048837293,0.08083323099999999,-0.002205999,-0.048943675,-0.063055691,-0.039078874,-1.279300033,-1.7774334509999998,-2.532206298,-1.9839397580000002,0.7942354559999999,0.729943097,-13.39802791,-14.04920962,-17.39055538,-10.1732344,-12.44954675,-12.92759339,-10.05899746,-9.054010444,-12.215377807617188,-15.567745208740234,-12.133102416992188,-14.184652328491211,-13.576360702514648 -2322,2322,L146F,-0.065970032,0.01890785,-0.092772345,-0.040227032999999995,-0.11858342699999999,-0.03242857,-0.148123025,0.016182961000000003,0.018552073999999998,0.036243687000000004,0.001572012,-0.066744833,-0.118799857,-0.104341355,0.02388729,-0.090847525,-0.146319328,1.482664884,2.390179978,-3.538987567,-4.526194229,-5.00133741,-2.008054482,-3.4508934780000002,-2.708458237,-4.053957397,-1.460972022,-6.529135704040527,-4.3448028564453125,-8.346586227416992,-7.5982537269592285,-6.177894592285156 -2323,2323,L146I,-0.033802792000000005,-0.028658412999999997,0.016936866000000002,-0.043869964000000004,-0.366678145,0.081841919,-0.029765597999999997,-0.037839986,0.27896421899999996,0.057756836,-0.115073662,0.034503156,-0.0006294240000000001,-0.082274613,-0.005465314000000001,-0.101368149,-0.631988141,1.365435683,2.278024303,-5.414389582999999,-7.610069427000001,-6.047276482000001,-4.49085981,-4.372623062,-4.551119133,-5.016967098,-0.285261651,-5.685891628265381,-8.546419143676758,-6.333759784698486,-7.406508445739746,-7.281502723693848 -2324,2324,L146H,-0.022100333,-0.029496453,-0.542275262,-1.85043568,-2.870012064,0.09952375699999999,-0.027946117000000003,-0.016254548,0.050633342000000005,-0.016846398999999998,-0.042146507,-0.333822509,-0.750728015,-1.577236408,-2.123634951,-2.673635185,-3.0663889419999997,1.6628242009999998,0.8642970870000001,-11.55926144,-12.21933997,-14.5518184,-9.100822281000001,-10.35627026,-11.56805628,-10.12035764,-9.384185772999999,-12.196002960205078,-13.861924171447754,-12.551299095153809,-14.33672046661377,-13.053282737731934 -2325,2325,L146K,-0.035675036,-0.938289933,-2.074359593,-2.52644914,-2.628974197,0.112475725,-0.0054643040000000006,-0.065885767,0.138027915,-0.5993507220000001,-1.277229143,-2.077449262,-2.071269924,-2.298690181,-2.754208099,-2.37389966,-2.884048733,0.521770104,-0.492694696,-12.48295839,-13.48456676,-15.429248499999998,-9.839793343,-11.16048743,-12.50069592,-10.12035764,-9.384185772999999,-12.349496841430664,-16.81052017211914,-14.216387748718262,-15.155158996582031,-15.574274063110352 -2326,2326,L146M,-0.13054608,-0.02725167,-0.093790518,-0.159891116,-0.136688725,0.02572644,-0.15458479,-0.106507369,-0.07616268,-0.043048221,-0.011455119,-0.14427626300000002,-0.043304772000000005,-0.107644104,-0.21213812699999998,-0.135317188,-0.138060261,1.487255086,2.265296799,-4.970610904,-6.93948941,-5.136935257,-3.775506607,-4.645992103999999,-4.355131142,-5.646593116,-2.9594584889999997,-6.642748832702637,-7.189661979675293,-7.145652770996094,-8.261772155761719,-7.810253143310547 -2327,2327,L146N,-0.048626605999999996,0.027940094,-1.139823056,-2.318061439,-2.571101493,0.072335759,-0.001589381,-0.09566383,0.260282006,0.041962569000000005,0.013917618999999999,-0.7919527740000001,-1.4876933380000001,-2.243642615,-2.392480263,-2.3188520930000003,-2.823350893,1.706674007,0.634807573,-11.55906459,-13.12404513,-13.79113685,-8.801671089,-10.30998032,-11.76848954,-8.961731592000001,-6.190365436,-12.34543228149414,-15.629804611206055,-13.510786056518555,-14.944609642028809,-14.566246032714844 -2328,2328,L146Q,-0.040662958,-0.041412686000000004,-0.088883041,-0.782644261,-1.8801027080000001,0.031166042,-0.021382519,-0.059943397,0.044881013,-0.07424534,-0.008580032,-0.176087711,-0.00167837,-0.397328631,-1.167959891,-2.177974156,-1.582231259,1.5909871580000001,1.324879616,-10.36511972,-11.25468963,-12.63250996,-8.33674614,-9.006149391000001,-10.59550349,-8.429290832000001,-6.190365569,-10.366023063659668,-14.00419807434082,-10.898039817810059,-12.337740898132324,-11.676915168762207 -2329,2329,L146P,-0.056003599,-1.035718776,-1.9764505980000002,-2.218807875,-3.3791381869999997,0.04566176,-0.057969232999999995,-0.054037964,0.09662822900000001,-0.835802699,-1.235634852,-2.061220048,-1.891681147,-2.118268931,-2.319346818,-2.846690924,-3.91158545,0.368269364,-0.581711185,-12.37640949,-13.02205361,-16.56278421,-9.019304909,-11.18262725,-12.09527749,-9.19881765,-6.6563888470000006,-11.577901840209961,-12.670245170593262,-12.2283353805542,-12.564022064208984,-12.755799293518066 -2330,2330,L146S,-0.06944122,-0.057805539,-1.415366165,-2.025867845,-2.745330081,0.079292052,-0.053679787,-0.085202653,0.098424322,-0.013868868999999999,-0.101742208,-1.257461942,-1.573270388,-1.846679647,-2.205056042,-2.751192899,-2.7394672630000003,2.515883397,1.10419167,-11.89824601,-12.72011503,-15.36214629,-8.827651711,-10.91869865,-11.66261837,-8.657114141000001,-6.0459106060000005,-11.398685455322266,-13.80498218536377,-12.208312034606934,-13.311223030090332,-12.691672325134277 -2331,2331,L146R,-0.043560151,-1.194805012,-2.174264603,-2.354320129,-3.4083901780000003,0.034947364,-0.058388322,-0.02873198,0.076177064,-1.088294476,-1.301315547,-2.22474517,-2.123784036,-2.078009304,-2.6306309530000003,-2.7552787739999998,-4.061501582,0.185175308,-0.6800990309999999,-12.52922387,-13.03829427,-15.92097142,-9.993565903,-11.13436214,-12.55892561,-10.12035764,-9.384185772999999,-12.997119903564453,-16.35979652404785,-13.458967208862305,-15.723803520202637,-14.269994735717773 -2332,2332,L146T,-0.079174973,-0.006270625,-0.08897277199999999,-1.066424827,-2.590170917,0.061118060999999994,-0.062686115,-0.09566383,-0.008730118,-0.047631847000000005,0.035090597,-0.10346370699999999,-0.074481836,-0.631877504,-1.500972149,-2.349304112,-2.831037722,1.6756821130000001,1.280096763,-10.0039412,-11.30785107,-13.44700188,-7.184416245,-8.678493317000001,-9.401943512,-7.285420492999999,-2.709396702,-8.641708374023438,-11.462183952331543,-9.879779815673828,-10.513348579406738,-10.197823524475098 -2333,2333,L146W,-0.077790712,-0.014155393,-0.070337283,-0.056477677000000004,-2.146566175,-0.037764442,-0.08587489400000001,-0.069706529,0.065356599,0.030424403,-0.05873518900000001,-0.046919935999999995,-0.09375463,0.01010614,-0.12306149300000001,-1.5683101609999999,-2.724822188,0.606928577,1.312592777,-7.33054118,-8.213073227,-10.80822818,-5.336289886,-6.307485695,-5.987628914,-6.582509977000001,-4.255336582,-10.643987655639648,-12.871389389038086,-12.813652038574219,-14.486471176147461,-11.7432861328125 -2334,2334,L146V,-0.043334429,-0.017956725,-0.078163187,-0.059673077000000005,-0.156148555,0.002177064,-0.09657579599999999,0.009906938,0.0019528120000000002,-0.041239599999999994,0.0053261509999999995,-0.07049134,-0.085835033,-0.056386773,-0.062959381,-0.157170161,-0.15512694900000001,1.482721905,2.2397079769999997,-4.417830127,-6.2298356020000005,-5.18535743,-2.135071175,-4.063368736,-4.4755176930000005,-3.748030633,0.473506039,-4.971487045288086,-7.577072620391846,-5.513909816741943,-6.778243064880371,-7.109648704528809 -2335,2335,L146Y,-0.106303734,-0.074100141,-0.103564794,-0.074514093,-2.1793686969999997,0.027281917000000003,-0.159495989,-0.053111479,0.14701145699999998,-0.033423573,-0.114776708,-0.098383169,-0.108746419,-0.026711982999999998,-0.12231620300000001,-1.680069295,-2.678668098,0.22949301800000002,1.298430085,-7.680214232999999,-8.520546555,-10.58918765,-5.7606217189999995,-6.965394066,-6.565321175,-6.578878692999999,-4.295425403,-10.2561674118042,-9.153318405151367,-12.109247207641602,-12.069958686828613,-10.790207862854004 -2336,2336,T147A,0.022062627,0.011389082,-0.010877535,-0.037556241000000004,-1.3871233980000002,0.017455101,0.055586450999999995,-0.011461197,-0.019409335,-0.038278711,0.061056874000000004,-0.069506412,0.047751342999999995,-0.059105944,-0.016006537,-1.399782544,-1.374464251,0.7544140859999999,1.331212557,-7.667339949,-6.604745415,-7.809783325,-8.900242683,-7.590012428,-7.431915893999999,-5.668000225,-2.258778971,-9.378080368041992,-13.032843589782715,-8.646831512451172,-6.667612075805664,-10.357949256896973 -2337,2337,T147C,0.038408812,-0.071621238,-0.03330638,-0.026731487,-0.308931309,0.009069435,0.027030176,0.049787447,-0.059343735999999994,-0.09728274099999999,-0.045959735,-0.077734839,0.011122078999999998,-0.06850722,0.015044247,-0.28005605,-0.337806568,1.617178365,2.167237634,-12.62910189,-11.64320908,-12.7559272,-13.86768423,-12.08303527,-12.79565366,-10.41234147,-7.632187008,-11.79531192779541,-16.38103675842285,-10.715495109558105,-11.8513822555542,-12.875085830688477 -2338,2338,T147E,0.08236563200000001,0.036530605,-0.026065612999999998,-0.02011953,-0.607522664,0.041221138,0.104538594,0.060192669000000004,-0.030326121,0.003195778,0.069865432,-0.096585245,0.04445402,-0.07545373400000001,0.035214674,-0.568999503,-0.646045825,1.693560615,1.946044848,-9.734872635,-7.394343208,-7.679792152,-12.37199245,-11.48108213,-9.747153229,-7.198864222,-1.835617294,-9.149078369140625,-16.27301025390625,-11.145090103149414,-5.086007118225098,-13.052942276000977 -2339,2339,T147D,0.090647072,-0.002851638,-0.014560061000000001,0.023919816,-0.909715515,0.076219948,0.137959369,0.043334774000000006,-0.048461132000000004,-0.029252546,0.023549271,-0.062427207,0.033307086,-0.0541024,0.10194203199999999,-0.841483357,-0.977947673,0.99741864,1.43980217,-10.12408034,-9.283466576,-8.565405701,-12.17729882,-10.87243678,-9.721793822999999,-5.957548871,-1.9213708919999999,-10.209150314331055,-17.04770851135254,-11.451493263244629,-5.5692667961120605,-13.295699119567871 -2340,2340,T147G,0.02756663,0.011423098999999999,0.00387799,-0.017565203999999997,-0.336406679,0.027825601000000002,0.044602592,0.010530666999999999,0.02597774,-0.020075564,0.042921760999999996,-0.044944569000000004,0.052700548,-0.054218974,0.019088567,-0.34415871600000003,-0.328654642,1.493917872,1.978015035,-8.392482777,-8.065321075,-7.210821907000001,-9.883424942000001,-8.858687683,-7.944158279,-6.126722202000001,-3.5776755639999998,-10.7912015914917,-14.769596099853516,-9.739341735839844,-7.197776794433594,-12.622966766357422 -2341,2341,T147F,0.004985754,-0.059418505999999996,-0.238903318,-1.704516287,-2.976655135,-0.001604902,0.045828717000000005,-0.03585721,-0.014846855,-0.10880212800000001,-0.010034884,-0.23292635399999997,-0.244880282,-1.5587357769999999,-1.8502967959999999,-3.043545443,-2.909764827,1.291544744,0.77133782,-13.0486452,-11.87626946,-13.73661357,-16.29012637,-11.90033024,-11.43988638,-8.951110965,-6.099940475,-13.210525512695312,-17.311269760131836,-13.79782772064209,-11.891210556030273,-16.58121681213379 -2342,2342,T147I,0.070851232,0.019368273999999998,0.032542448,0.006371238,-1.282457123,0.026742172,0.11355024699999999,0.028152216,-0.04843592,-0.000648761,0.039385308,-0.024102044,0.08918694,-0.041968240999999996,0.054710717,-1.0622079759999998,-1.5027062690000001,0.8348817470000001,1.367458187,-11.37532434,-11.65940349,-11.77472894,-11.738057300000001,-11.47842925,-10.226002699999999,-9.361592344,-5.859069174,-9.854316711425781,-15.079696655273438,-10.840739250183105,-9.433753967285156,-11.994209289550781 -2343,2343,T147H,-0.022954948,-0.032115741,-0.055724518,-0.076693398,-1.292782142,0.089525634,0.032493844,-0.078403739,-0.032644024,-0.00479925,-0.059432232,-0.052569169000000006,-0.058879867,-0.083738746,-0.06964805,-1.200500238,-1.3850640459999999,0.970922935,1.3738640530000001,-12.00539479,-11.795002,-12.12862101,-12.771757899999999,-11.39212447,-11.93946858,-7.917691062,-3.4287596610000004,-11.618083000183105,-15.729610443115234,-11.642308235168457,-9.056638717651367,-13.569463729858398 -2344,2344,T147K,-0.046906224,-0.033257449,-0.055360768,-0.070045941,-0.501617593,0.078192462,0.019628974,-0.11344142199999999,-8.01e-05,-0.047788552000000005,-0.018726345,-0.121651196,0.010929661,-0.084515437,-0.055576444,-0.493784444,-0.5094507420000001,1.7021810290000001,1.992870018,-11.71117919,-11.44621854,-13.72228281,-12.25580257,-9.982599548,-11.14899247,-7.110757453,-2.9004900680000003,-10.318153381347656,-16.945880889892578,-10.754897117614746,-7.856783390045166,-12.059910774230957 -2345,2345,T147M,0.034932628,0.038274469,0.02025315,0.015128206000000002,-0.314493285,0.024504612999999998,0.08402587800000001,-0.014160622,-0.044782406,-0.039434512000000005,0.11598345,-0.044453791,0.08496009,-0.047215279000000006,0.077471691,-0.323032402,-0.305954168,1.0213265740000002,1.661118937,-9.26300276,-9.731393074,-9.440511238,-9.684614571000001,-9.230287392000001,-8.228207527,-7.343513146,-3.825057316,-10.392315864562988,-14.104033470153809,-10.794440269470215,-9.727989196777344,-12.177289962768555 -2346,2346,T147L,-0.017113803,0.014193303999999999,-0.018917853999999998,-0.01216079,-1.710683524,0.030979958,0.024882067,-0.059109673,-0.04991600400000001,0.013444981000000002,0.014941626000000001,-0.043432969,0.0055972619999999996,-0.025622002,0.0013004219999999999,-1.573302796,-1.848064251,0.584183557,1.3113530979999999,-12.88251127,-13.20701052,-14.39724349,-13.18123598,-13.13496415,-10.4921022,-9.720364342,-6.657958814,-10.77663803100586,-15.570138931274414,-12.260746002197266,-9.790907859802246,-13.790279388427734 -2347,2347,T147N,-0.038856954,-0.08720346400000001,-0.043146294,-0.057624507,-0.119655975,0.051518822,-0.030319695,-0.047394213,0.018634618000000002,-0.072463634,-0.101943293,-0.093209145,0.006916556999999999,-0.08175471599999999,-0.033494297,-0.109720839,-0.12959111,1.554629113,2.398005756,-6.042720021,-6.414056778,-5.1149969639999995,-7.758409164,-5.018322853,-5.907814346,-5.7644382279999995,-0.19384504600000002,-8.85113525390625,-13.820112228393555,-8.635418891906738,-6.209679126739502,-10.187488555908203 -2348,2348,T147Q,0.049848489,-0.064887079,-0.006934806,-0.026956711,-0.223975582,0.056022228,0.082244629,0.017452349,0.006748488,-0.036449277,-0.09332488,-0.034783121,0.020913509,-0.029826983999999997,-0.024086437999999998,-0.141638347,-0.306312817,1.364063412,2.208153016,-9.635149107,-8.835056831000001,-9.019253609,-10.2383288,-10.51477368,-9.568332611,-5.359546412,-1.408534912,-8.867215156555176,-16.158565521240234,-10.020227432250977,-7.15170431137085,-11.33480453491211 -2349,2349,T147P,-0.002512085,-0.038981717,-0.012788896999999999,-1.30489685,-2.288112346,0.059525180999999996,0.025272633,-0.030296802999999997,-0.039177797,-0.035082581,-0.042880853,-0.06491985,0.039342056,-0.786656523,-1.823137176,-2.1311938980000003,-2.445030793,1.920090641,1.380818631,-13.16452117,-12.26979005,-13.956599300000002,-13.67329617,-13.13581473,-12.78710557,-9.292108657,-5.448707295,-9.858223915100098,-16.64374351501465,-11.06814193725586,-9.96825122833252,-14.060014724731445 -2350,2350,T147S,0.021301805,-0.005765296,0.010263309,-0.032975752000000004,-0.098120435,-0.002349005,0.036401396,0.006202213000000001,0.003624683,-0.036191008,0.024660416,-0.030810097999999998,0.051336716,-0.0467495,-0.019202003,-0.10393918199999999,-0.092301687,1.4178042830000002,2.340412478,-7.468601903,-7.192710915,-6.892370529,-8.909827095,-7.185879974,-7.162221001,-6.672827462000001,-3.9442720639999997,-7.988670825958252,-10.359256744384766,-6.9056077003479,-7.109995365142822,-9.814542770385742 -2351,2351,T147R,0.037036407,0.019985377,0.019748768,-0.0036298090000000003,-0.122255423,0.145202149,0.087494768,-0.013421954,-0.09962322400000001,0.018774986,0.021195767,-0.047824899000000004,0.087322435,-0.050615138,0.04335552,-0.161346192,-0.083164653,1.629188205,2.365289872,-10.84258707,-10.94889198,-11.72583983,-9.769808487,-9.800727448,-11.96766761,-6.577469245,-2.207437122,-10.911886215209961,-16.488250732421875,-10.549345016479492,-9.049967765808105,-12.824566841125488 -2352,2352,T147W,0.014383551999999999,-0.0013591760000000001,-0.008024587,-0.893420022,-2.021586879,0.030176718999999998,0.042105385,-0.013338281,-0.030263125,-0.058050397999999996,0.055332047,-0.07150786599999999,0.055458692999999996,-0.514089079,-1.272750965,-1.87461456,-2.168559198,1.787464926,1.449327755,-13.96691795,-13.02773247,-14.85883616,-15.0155601,-13.23193417,-13.70052685,-9.283797723,-6.099940577999999,-14.560297012329102,-19.604856491088867,-15.001707077026367,-12.955204010009766,-18.23860740661621 -2353,2353,T147V,0.072394674,0.058004098,-0.001758824,-0.029396437999999997,-0.09750000199999999,-0.0005054980000000001,0.091685169,0.053104179,-0.05681135599999999,-0.021290375,0.13729857,-0.096363315,0.092845668,-0.059741442,0.0009485660000000001,-0.154209305,-0.040790698,1.4252966230000002,2.215574258,-10.1901212,-10.381015199999998,-10.45105201,-9.946382339,-10.22518117,-9.946975304,-8.756306696000001,-5.263357834,-8.906091690063477,-15.700931549072266,-10.755334854125977,-8.555645942687988,-12.306763648986816 -2354,2354,T147Y,-0.019430118,-0.034379109,0.009364239,-1.5980526519999998,-2.680316153,0.062267874,0.026428242999999997,-0.06528847900000001,-0.031025482000000004,-0.040684114,-0.028074104,-0.049917475999999995,0.068645953,-1.4228583559999999,-1.7732469469999999,-2.583775144,-2.776857161,0.622004561,0.7097921140000001,-14.90103684,-13.80006189,-15.17759801,-17.60993013,-13.42868655,-14.48890765,-10.12983299,-7.15000833,-12.918892860412598,-18.363807678222656,-14.008758544921875,-10.199827194213867,-16.553539276123047 -2355,2355,A148C,0.0016441960000000001,-0.002224891,-0.05808538,0.005528764,-0.15431756300000002,0.017589066,0.0065150569999999994,-0.003226665,0.016128025,0.010538252,-0.014988033999999999,-0.09213560900000001,-0.02403515,-0.036644692,0.047702219000000004,-0.091848011,-0.21678711399999998,1.462228225,2.3775213859999997,-6.681457357999999,-6.161983977999999,-6.971356865,-7.38091674,-5.801538077999999,-7.091491127,-7.888532184,-6.325314992999999,-9.570954322814941,-10.770543098449707,-9.08015251159668,-9.649205207824707,-10.241418838500977 -2356,2356,A148E,0.0288149,0.029431551,-0.0790964,-0.0012719769999999999,0.024932066,0.00027529,-0.010665198999999998,0.06829499900000001,0.084247633,-0.006363376,0.065226477,-0.084475779,-0.073717021,-0.049774439000000004,0.047230485,-0.057088846,0.10695297699999999,1.4150974180000002,2.441672406,-1.659040453,-1.763940895,-1.3824569169999998,-2.190363571,-0.602351685,-2.356089195,-3.766807434,-1.085094486,-5.006714344024658,-4.802777290344238,-4.636753082275391,-4.943742752075195,-5.750759601593018 -2357,2357,A148D,-0.03426742,-0.0007987010000000001,-0.014351461999999999,-0.008885485,-0.013729766000000001,-0.011685063999999998,-0.067733818,-0.0008010210000000001,0.09204178199999999,0.018704847,-0.020302248999999998,-0.010116199000000001,-0.018586724,-0.007687123000000001,-0.010083846,-0.024493481,-0.00296605,1.237023233,2.517427644,-1.774264165,-1.990384323,-1.663711395,-1.800460587,-1.169771034,-2.246993485,-4.012036294,-1.4869570090000002,-4.751289367675781,-4.772622108459473,-4.657708168029785,-4.627998352050781,-5.8482208251953125 -2358,2358,A148G,0.033317532000000004,0.015772027,-0.018914038,-0.012160497,-0.016463353,0.000937439,0.02479992,0.041835144,0.052060125,-0.012909008999999999,0.044453062,-0.082076356,0.044248280999999993,-0.021801378,-0.002519616,-0.063288497,0.030361792000000002,1.339784948,2.420667763,-2.8712081119999997,-2.6944537810000004,-2.8946206969999997,-2.913121948,-2.687377182,-3.1664669489999997,-4.146690507,-2.349109237,-5.587292194366455,-6.224203586578369,-4.584981441497803,-5.132396697998047,-6.093055725097656 -2359,2359,A148F,0.09529546300000001,-0.049373701,0.0037776290000000002,0.002475958,-0.031785314,0.069537373,0.056005760999999994,0.134585165,0.045076019,-0.08527966,-0.013467742,-0.101047341,0.10860259900000001,-0.047828324000000005,0.05278023900000001,-0.061469181,-0.002101447,1.333538799,2.44493706,-6.91025022,-5.62188427,-7.185521698,-8.247621376,-5.747433022,-7.748790733,-7.570707088,-5.757002846000001,-8.861001968383789,-10.3079195022583,-8.073957443237305,-9.674864768981934,-9.328275680541992 -2360,2360,A148I,0.061226822,0.035919322000000004,-0.037801537999999996,0.095323611,0.019962406000000002,0.182397643,0.054101554,0.068352089,-0.073272386,0.072767756,-0.000929112,-0.078855077,0.003252002,0.021437295,0.169209926,0.055313439000000006,-0.015388628,1.259491033,2.8930176839999997,-6.083708322000001,-5.5475877229999995,-6.207755402,-6.327977897999999,-4.855540756,-7.479679832,-7.029212641,-5.311291291,-7.420440673828125,-9.121696472167969,-6.302057266235352,-7.753942966461182,-7.69492244720459 -2361,2361,A148H,0.047705551,0.018955911000000002,-0.020074345,0.03410161,-0.0026922020000000003,0.012621841000000002,0.03143757,0.063973532,0.053151119000000004,-0.015341282,0.053253104,-0.041827197,0.0016785079999999998,-0.030146851000000002,0.098350071,-0.036758658,0.031374255,1.2707848640000001,2.459244756,-3.7366857889999996,-3.0361629260000003,-4.153887299,-4.081775177,-2.980743317,-4.430860228999999,-4.534694789,-3.2314832260000004,-6.34853982925415,-6.8622589111328125,-5.690706253051758,-5.196208953857422,-6.319493293762207 -2362,2362,A148K,0.005032661,0.047761797,0.016127241,-0.038354341,0.03095493,0.058522425,0.003800514,0.006264808,0.048260101,0.030428302999999997,0.065095291,-0.004903119,0.037157601,-0.04934697,-0.027361711,0.052547474000000004,0.009362386,1.12299802,2.676988626,-2.238199545,-2.071065842,-2.57423922,-3.281260521,-0.622791718,-2.641640427,-3.6090427910000002,-1.286113865,-5.9139604568481445,-6.978097915649414,-4.542828559875488,-5.359157562255859,-5.8120503425598145 -2363,2363,A148M,0.136325088,-0.047523380999999996,-0.005670045,-0.084710624,0.033247698,-0.12731969,0.106028778,0.166621397,-0.23297322899999998,-0.090576,-0.0044707620000000005,-0.20212418899999998,0.19078409899999998,-0.052708872000000004,-0.11671237599999999,-0.09128435800000001,0.157779753,1.360739959,2.268562279,-5.380625565,-5.116868408,-5.454628639,-6.054601097000001,-4.368098282,-5.908931396,-6.541269375,-4.498290021,-8.181591033935547,-8.929126739501953,-7.132810592651367,-8.601415634155273,-8.063386917114258 -2364,2364,A148L,0.027296894,0.029859424,0.010759302,0.050459807,0.047229992,0.024906584,-0.00182183,0.056415617,0.068215124,0.054789045999999994,0.004929801,-0.012046606999999999,0.03356521,0.027391367000000003,0.07352824599999999,0.027262911,0.067197073,1.339338372,2.847961086,-4.790198767,-4.205386505,-5.262026917,-5.245268135,-3.469557289,-5.76875499,-5.2175746610000004,-3.3823775510000003,-6.539369583129883,-7.312074661254883,-5.222170352935791,-6.572023391723633,-6.7977519035339355 -2365,2365,A148N,0.008472485,-0.0092706,-0.015659933,0.071364457,-0.021430817,0.025021053999999997,-0.000344803,0.017289772,0.042522971,0.021274362999999998,-0.039815563,-0.015813765,-0.015506101000000001,0.085178034,0.05755088,-0.000203889,-0.042657744000000004,1.3201650059999999,2.677285894,-2.989942674,-2.680794739,-3.110477608,-3.7479957280000002,-2.103064224,-3.307381073,-4.831246384,-2.185656255,-5.5248703956604,-5.939157009124756,-5.543566703796387,-5.053916931152344,-5.839825630187988 -2366,2366,A148Q,-0.011222939,0.026698921,-0.032164215,0.026740219,-0.032812593,0.0052951840000000005,-0.035682211,0.013236333999999999,-0.012347107,0.018140804,0.035257038,-0.051949875,-0.012378555,-0.008998987,0.062479425,-0.066096798,0.000471613,1.324961646,2.4028156430000003,-1.976998178,-1.467542244,-2.018750351,-2.7859823460000004,-0.94172773,-2.67098822,-3.846641902,-1.067410795,-4.647702217102051,-4.279396057128906,-4.094725131988525,-3.8240180015563965,-4.892407417297363 -2367,2367,A148P,0.015720608,0.021313852999999997,-0.026915419,0.006047456999999999,-1.3817948759999998,0.054266300999999996,0.019659568,0.011781647,0.03050882,0.002240727,0.040386978999999996,-0.057372285999999995,0.003541448,-0.013512756,0.02560767,-1.416467434,-1.347122318,0.6040975439999999,1.319491312,-5.487982811,-4.680855011,-5.014827553,-6.391617073,-4.928239288,-6.42437513,-6.8910845489999994,-4.482013792,-9.098187446594238,-10.681711196899414,-7.624942302703857,-9.35328197479248,-11.024702072143555 -2368,2368,A148S,0.024507357,-0.028076865,-0.014147682,0.01260874,-0.047102173,-0.016079443,0.001503791,0.047510922000000004,0.041785972000000005,-0.003936943,-0.052216785999999994,-0.049767285,0.021471921,-0.016028352,0.041245831000000004,-0.051366209,-0.042838136,1.272351541,2.38649509,-1.860157939,-1.620459145,-1.91235936,-2.681492973,-1.1387024,-1.9477758180000002,-2.678527456,-1.8424915530000001,-5.197628021240234,-4.9278669357299805,-4.627885818481445,-5.070987701416016,-5.115238189697266 -2369,2369,A148R,0.056977379,0.012031408,0.00509983,0.0177334,0.019409463000000002,0.0050142979999999995,0.04299103,0.070963728,-0.026528983,-0.005931158000000001,0.029993972999999997,-0.06449213,0.07469179,-0.025674942000000003,0.061141741,-0.038595071,0.077413997,1.331553658,2.489237444,-1.5384619169999998,-1.090633202,-2.005216446,-1.496868355,-1.117170029,-1.982421555,-3.025063717,-0.7768873359999999,-4.95542049407959,-5.860692024230957,-3.673171043395996,-4.109073638916016,-4.85811710357666 -2370,2370,A148T,0.032737141000000004,-0.020103024,-0.020914089,-0.004093654,-0.040016796,0.014325465,0.027633235,0.037841046,0.053397299,-0.006777759,-0.033428288,-0.071073467,0.02924529,-0.021286575,0.013099268,-0.020720102,-0.059313489000000004,1.278865205,2.3815814459999998,-2.09942028,-1.9365991359999999,-2.13792115,-2.356985512,-1.241464745,-2.824130859,-3.291314823,-2.200589491,-4.7421393394470215,-4.966819763183594,-4.67789888381958,-5.131838321685791,-5.254744529724121 -2371,2371,A148W,0.10885759,0.076481021,0.028562625,0.030399474,-0.039664242,0.016883383999999998,0.12680037,0.090914809,0.050402028,0.016604056000000002,0.136357985,-0.018903023999999997,0.076028274,-0.007527521999999999,0.068326469,-0.1208961,0.041567616,1.374599104,2.294895244,-6.504989421,-5.489832855,-6.790646561,-7.228506317000001,-5.799230782,-7.216730591,-7.403794182,-5.431339991000001,-10.174310684204102,-12.155616760253906,-9.625772476196289,-10.162675857543945,-10.310142517089844 -2372,2372,A148V,0.05349313,-0.008821716,-0.044994692999999995,-0.011312445,0.0030992859999999997,0.058461331,0.04827026,0.058716,0.007038365,-0.05089029,0.033246859,-0.096467144,0.0064777590000000005,-0.047258802999999995,0.024633914,-0.072213103,0.078411674,1.37892799,2.3714800169999997,-4.364630952,-3.877420654,-4.545561493,-4.858937019,-3.408264175,-5.13297142,-5.300264652,-3.87726509,-6.1459269523620605,-7.351217269897461,-5.141787528991699,-6.509582042694092,-6.67064905166626 -2373,2373,A148Y,-0.017991726,-0.080737102,-0.09841883300000001,-0.00284377,-0.126288959,0.056337440999999995,-0.042099011,0.00611556,0.139031045,-0.029850715,-0.131623489,-0.063297139,-0.133540527,0.018695358999999998,-0.024382899,-0.08897595,-0.16360196800000001,1.336557061,2.30175345,-7.081957329,-5.790491272000001,-7.40847879,-8.332373131,-5.808967094,-8.069476357000001,-7.693808579,-5.85464797,-8.871267318725586,-10.143779754638672,-8.04464054107666,-8.670341491699219,-8.484148979187012 -2374,2374,F149A,0.040286465,0.060909383,-0.016501785,-0.033655895,-0.582402575,0.004158413,0.027562535,0.053010394,0.002018804,-0.012020147,0.133838913,0.006837811,-0.03984138,0.01999157,-0.08730336,-0.43038805399999996,-0.7344170959999999,0.783446995,1.492646231,-10.32655865,-8.020104247999999,-12.62823712,-13.61807543,-8.830995232000001,-8.535381218,-4.733122938,-1.519623259,-8.743436813354492,-11.269412994384766,-9.409529685974121,-9.470542907714844,-11.239325523376465 -2375,2375,F149C,0.059576734000000006,0.09486982699999999,0.011257841999999999,0.022014554,-1.6169616740000001,0.094867855,0.06525333,0.053900137,0.017271263999999998,-0.026734301000000002,0.216473954,0.036872501,-0.014356817,0.027727401000000002,0.016301706000000003,-1.535603302,-1.698320045,0.649342845,1.31668358,-10.96814646,-9.097073029,-12.38646564,-11.76214357,-11.37881529,-10.21623479,-7.124339075,-3.3659497710000004,-9.870317459106445,-10.286962509155273,-10.769606590270996,-8.938433647155762,-11.178430557250977 -2376,2376,F149E,0.002007039,0.100715267,0.011505175,-0.020404046000000002,-1.318017717,-0.022971041,0.06354565599999999,-0.059531577999999995,0.022476537,-0.038484626,0.239915159,0.031961601,-0.008951251,-0.003285342,-0.037522749,-1.164231735,-1.4718036980000002,0.740227027,1.3485844009999999,-12.04548338,-9.609107071,-13.79513521,-14.16214963,-9.853826377999999,-12.80719863,-6.556943344,-2.382055233,-10.033552169799805,-11.688289642333984,-9.415112495422363,-11.767285346984863,-12.73282241821289 -2377,2377,F149D,0.007066676,0.044556634000000005,-0.002155516,-0.006561474,-1.7228140019999998,0.048427541,0.069722747,-0.055589396,0.044351910999999994,-0.0014249579999999998,0.090538225,0.014626422,-0.018937453,0.05407933,-0.067202278,-1.55433228,-1.891295723,0.8001617659999999,1.3251937329999999,-13.45469605,-10.57104749,-15.11081541,-16.21398959,-12.19730969,-13.18031808,-6.550279201,-3.52725783,-10.920812606811523,-12.249037742614746,-10.921393394470215,-12.578204154968262,-13.72562026977539 -2378,2378,F149G,0.053034822999999995,0.099121435,0.03770568,-0.547502585,-1.767180068,0.055481447999999996,0.069452643,0.036617002,-0.026048857,-0.020379766,0.218622635,0.032775096000000004,0.04263626400000001,-0.174326874,-0.920678296,-1.83891709,-1.6954430459999998,1.104288071,1.326902868,-13.12006158,-11.31522638,-13.94873898,-15.644071499999999,-11.75544701,-12.93682403,-6.647444075,-3.8199867860000003,-10.190470695495605,-13.364707946777344,-11.293551445007324,-11.156607627868652,-13.591714859008789 -2379,2379,F149I,-0.000160379,0.08338429900000001,0.024293341,0.020608355,-0.067300137,0.021107062000000003,0.020140911,-0.020461668,-0.044551123,-0.004759439,0.17152803600000002,0.051608954000000005,-0.0030222720000000003,0.071175591,-0.029958882000000003,-0.040222255,-0.09437801800000001,1.29224426,2.637785846,-9.864096999,-7.527008522,-11.36589468,-11.49187062,-8.799048767,-10.1366624,-5.636649128999999,-2.821442962,-8.989692687988281,-12.106760025024414,-9.299808502197266,-9.146488189697266,-10.6769380569458 -2380,2380,F149H,0.039914892,0.063269795,0.026776955,-0.005875142,-0.5655513120000001,0.060617624,0.047965500999999994,0.031864283,0.0333586,-0.022989452999999997,0.149529043,0.0338525,0.019701409,-0.017772798,0.0060225140000000005,-0.48056964700000004,-0.650532977,1.316234439,1.7582979380000001,-10.05514,-9.670787354,-11.05214809,-10.71742863,-9.917519172999999,-8.91781678,-6.397315547000001,-3.7877049439999997,-7.53268575668335,-8.375335693359375,-7.587893486022949,-9.930849075317383,-10.220633506774902 -2381,2381,F149K,-0.032924389,0.056922600999999996,-0.039732013,-0.027358441,-1.31821425,0.006102804,0.09144520699999999,-0.157293985,0.034573498,-0.07316903400000001,0.18701423600000003,-0.044619877,-0.034844148,0.00149909,-0.056215970999999997,-1.3600670519999998,-1.276361447,0.768398305,1.335675711,-12.82191288,-10.05416396,-14.53259662,-15.00312672,-12.18763982,-12.33203728,-6.085602987000001,-3.3557139210000004,-9.9319429397583,-13.564878463745117,-8.756781578063965,-13.927959442138672,-12.378108024597168 -2382,2382,F149M,0.098619145,0.09203110800000001,0.09320669,0.054909558,-0.010095765,-0.017257939,0.121460043,0.075778246,0.017887995,-0.048266539000000004,0.232328755,0.06885951900000001,0.11755386,0.06502738799999999,0.044791727,-0.042547497999999996,0.022355969,1.2452987340000001,2.5215486940000003,-8.597977412,-7.402101852,-10.51820609,-7.70014254,-9.020210724,-8.349225853,-6.05753849,-2.609377384,-8.51522445678711,-10.338251113891602,-8.512398719787598,-9.154886245727539,-9.52446174621582 -2383,2383,F149L,0.031110656,0.08866229199999999,0.038625162000000005,0.005882525,-0.262966181,0.0029214809999999996,0.06753949299999999,-0.005318181999999999,0.007627269,0.012389997,0.164934587,0.090663226,-0.013412903,0.037997477,-0.026232427000000003,-0.20178135100000003,-0.32415101,1.4954448040000001,2.219955252,-6.984806213,-5.887959732000001,-8.16932563,-6.538271187,-6.598287506,-7.730187012000001,-4.301733502,-1.364094085,-7.552537441253662,-9.182326316833496,-7.048330783843994,-7.523778915405273,-8.248329162597656 -2384,2384,F149N,-0.035530906,0.096952001,0.046421682,-0.03676396,-1.70591085,0.035952536,0.015378863000000001,-0.08644067400000001,0.0016239660000000001,0.007943888,0.18596011399999998,0.055679455,0.037163907999999996,0.069249593,-0.142777512,-1.571662167,-1.840159532,0.49966365799999996,1.30860262,-13.40351785,-10.85361479,-15.65903705,-14.94843861,-13.17108476,-12.38541405,-7.3324377489999994,-4.634775901,-10.134961128234863,-12.01834774017334,-10.093388557434082,-11.674212455749512,-12.462414741516113 -2385,2385,F149Q,0.035587671,0.134240325,0.00973854,-0.019069881,-1.0905521870000001,0.011499466000000002,0.07252898099999999,-0.00135364,-0.021115167999999997,4.26e-05,0.268438049,0.030281542,-0.010804463,0.004505474000000001,-0.042645235999999996,-0.644967547,-1.536136826,0.717539268,1.408916111,-12.86427143,-9.642229324,-14.19237731,-15.31577441,-11.83568346,-13.33529263,-5.995322775,-3.1922848339999996,-9.48102855682373,-11.387205123901367,-8.493169784545898,-10.893365859985352,-11.255274772644043 -2386,2386,F149P,-0.000369375,-0.851965643,-1.979390965,-2.3406094630000003,-3.1968574810000003,0.057785030999999994,-0.0033126109999999996,0.002573862,0.086561395,-0.615921449,-1.088009836,-1.8986676219999998,-2.060114307,-2.084839961,-2.596378965,-2.7446129389999996,-3.6491020219999997,2.8535484639999997,0.9404147890000001,-15.89338192,-13.48252468,-18.03496117,-17.64867516,-15.51378389,-14.78696469,-10.21044336,-9.087452226,-11.311734199523926,-14.989006042480469,-12.701238632202148,-13.798652648925781,-16.801170349121094 -2387,2387,F149S,0.027881156,0.074545352,0.015578222,-0.002463083,-1.357072082,0.02949975,0.022319651,0.033442661,-0.028270099,-0.016346511,0.165437215,0.053527276,-0.022370832,0.043077329000000004,-0.048003494,-1.185682257,-1.5284619069999998,0.770383588,1.3473931469999998,-11.10537738,-8.752261269,-13.46157404,-12.66738418,-11.02219539,-9.623472031,-6.048349197,-2.637172638,-8.84795093536377,-11.236802101135254,-9.955431938171387,-9.508743286132812,-11.253981590270996 -2388,2388,F149R,0.059749899,0.128760614,0.07071086900000001,0.021153243,-1.3596861269999998,0.040158888999999996,0.07277262400000001,0.046727174,-0.010827301999999999,-0.008139344,0.265660571,0.071548657,0.06987308099999999,0.053551967,-0.011245481000000002,-1.28173653,-1.4376357240000002,0.561401425,1.323358187,-12.06967206,-8.664966179,-12.68169221,-15.31616233,-12.47617533,-11.20936423,-6.333587406,-1.402821157,-9.049599647521973,-12.511467933654785,-8.771435737609863,-12.316620826721191,-12.004719734191895 -2389,2389,F149T,0.0018859760000000001,0.079642171,0.025121984,-0.016112233,-0.633217506,0.013003385,-0.004325725,0.008097677,-0.04428184,0.004936383,0.154347959,0.08625588199999999,-0.036011915,0.028957785,-0.06118225,-0.46292296299999997,-0.8035120490000001,0.773657927,1.476857317,-11.29191496,-8.188310486,-14.13101454,-14.11273743,-11.52987959,-8.497632759,-5.6749769070000005,-1.259765276,-7.986555576324463,-11.446579933166504,-9.123567581176758,-9.287996292114258,-10.444053649902344 -2390,2390,F149W,0.06461485,0.10923530199999999,0.034816718999999996,0.018352703999999997,0.10653064699999999,-0.027555102,0.054669802999999996,0.074559897,0.040985026,-0.045089955,0.263560558,0.02369736,0.045936078,-0.00828885,0.044994257,-0.000490258,0.213551552,1.1989643,2.538207767,-5.671315671,-5.280903953999999,-5.410339088,-4.612119034,-5.85590226,-7.197314017999999,-4.5969943010000005,-1.5418668969999998,-5.637016773223877,-6.590334892272949,-3.943626880645752,-8.275360107421875,-9.050373077392578 -2391,2391,F149V,-0.019289679,0.07274538,0.026812948,-0.045842744000000005,-0.43459985799999995,0.006302969,0.015632935,-0.054212292999999995,-0.04718747,-0.030341485,0.175832244,0.082483339,-0.028857444,0.02851307,-0.120198557,-0.317187056,-0.55201266,0.9360036140000001,1.647982485,-9.942329851,-7.447230835,-12.22129475,-11.89783201,-8.510326088,-9.634965576,-6.237694734,-1.9306202540000001,-8.111130714416504,-11.17126750946045,-9.060464859008789,-8.395936012268066,-10.602962493896484 -2392,2392,F149Y,0.044560399,0.06797758599999999,0.03486357,0.002598509,0.016628017,-0.070360452,0.07456057599999999,0.014560222,-0.022265617999999997,-0.016635298,0.15259047,0.017400775,0.052326365,-0.017019532,0.02221655,0.018287433999999998,0.0149686,1.120864082,2.612443991,-2.7349216710000004,-2.394275696,-2.887829697,-2.43709314,-3.458864502,-2.496545319,-2.132023946,-0.7033977779999999,-4.746325969696045,-5.269679069519043,-4.883908271789551,-5.731413841247559,-5.370495796203613 -2393,2393,L150A,-0.023584839,0.001733995,0.027900282999999998,0.02703957,-0.21227069399999998,0.052746188,-0.031796765,-0.015372911999999999,0.03156621,-0.018118727,0.021586716000000002,0.039731819,0.016068746999999998,0.046827815999999994,0.0072513230000000005,-0.167394494,-0.257146893,1.2036966340000002,2.047301484,-8.144220461,-8.71687999,-8.895113777,-7.504944878,-5.44997477,-10.15418889,-4.693826241,-0.821271685,-8.151601791381836,-10.048234939575195,-4.844841003417969,-6.698846340179443,-8.304925918579102 -2394,2394,L150C,-0.002671534,0.00739807,0.021204176,0.020484061,-0.476126661,0.013315117,0.013900976,-0.019244043,0.032001343,0.01337604,0.0014200999999999999,0.058969542,-0.016561191,0.06760157900000001,-0.026633457000000003,-0.35071296700000004,-0.601540355,0.564801113,1.4576833619999998,-11.18288795,-12.37227635,-12.47233546,-10.29001392,-10.07531344,-10.70450057,-5.6860909479999995,-2.208912991,-8.570083618164062,-11.094510078430176,-6.562910079956055,-7.498306751251221,-9.51192855834961 -2395,2395,L150E,-0.08837166699999999,-0.093591989,-1.219768392,-2.190217996,-2.8788484210000003,0.090897126,-0.077625975,-0.099117359,0.106920165,0.059886385,-0.247070362,-0.784071574,-1.65546521,-1.6570080969999998,-2.723427894,-2.8440027189999997,-2.913694122,2.139324044,1.036520662,-14.81219449,-14.91566449,-15.96125401,-14.81466446,-13.16431033,-15.20507917,-9.030679088,-7.110701665,-13.390536308288574,-16.23631477355957,-11.24966812133789,-16.00267791748047,-15.464645385742188 -2396,2396,L150D,-0.148466565,-0.409866169,-1.311951202,-1.787175184,-2.440127655,0.0647391,-0.154956903,-0.14197622699999998,0.025955715,-0.13442969400000002,-0.685302643,-1.428510164,-1.195392239,-1.749553305,-1.824797063,-2.497215233,-2.383040076,3.285344165,1.737945696,-16.20151136,-15.98421342,-17.80841623,-15.97809306,-14.20976674,-17.02706735,-9.964609497,-9.414628367,-14.568777084350586,-18.151973724365234,-12.218579292297363,-17.30778694152832,-16.99527359008789 -2397,2397,L150G,-0.037781783,0.053545522000000005,0.026022831,-0.238188437,-1.7566855730000002,0.07305187,-0.023828772999999998,-0.051734793,0.054184264,-0.008015019,0.11510606300000001,0.004452308,0.047593353,-0.017776003000000002,-0.458600871,-1.849582597,-1.663788548,0.866081733,1.311837357,-13.51054475,-13.66037441,-14.50035725,-13.242819500000001,-11.10401696,-15.04515563,-7.128239392999999,-4.23882271,-10.685051918029785,-16.51287078857422,-8.815650939941406,-12.390090942382812,-12.916385650634766 -2398,2398,L150F,-0.06644371,0.063259295,0.0030953609999999996,0.031013823,-0.14995674,0.09609187400000001,-0.005511754000000001,-0.127375666,0.04734172,0.088658128,0.037860461,0.029646777000000003,-0.023456056,0.167080067,-0.10505242099999999,-0.06585146900000001,-0.23406201,1.543610422,3.106887046,-4.9230298569999995,-3.9379356839999997,-7.327540894,-4.555425735,-4.754539436,-4.039707535,-4.322044208,-1.474033409,-6.916429042816162,-9.92902660369873,-5.4698028564453125,-6.951406478881836,-6.079213619232178 -2399,2399,L150I,-0.035805746,0.005854104000000001,0.026517584,0.012605325,-0.107601528,-0.063500446,-0.052608076,-0.019003415,0.242143943,-0.006801819000000001,0.018510026000000002,0.067094497,-0.01405933,0.0276528,-0.00244215,-0.06964445799999999,-0.145558598,1.377796773,2.5008891269999998,-5.7350223279999994,-4.868571037,-7.175873985,-6.208252174,-4.025719948,-6.396694496,-4.466925568,-0.9854577309999999,-6.927506446838379,-6.787128448486328,-4.835489273071289,-6.414612293243408,-6.965812683105469 -2400,2400,L150H,0.010326974000000001,-9.84e-05,0.013194441999999999,-0.68746154,-2.50799963,0.051910324,0.032624475,-0.011970528000000001,0.148082516,-0.006530045,0.006333318,-0.026236669,0.052625553,-0.279213223,-1.0957098570000001,-1.947073041,-3.0689262189999997,1.346444244,1.341517906,-14.98430627,-16.49960552,-16.56049813,-13.94391112,-13.26248879,-14.65502776,-9.170114389,-7.110701665,-11.645078659057617,-15.67912483215332,-11.353799819946289,-15.567657470703125,-14.009246826171875 -2401,2401,L150K,-0.18199730100000003,-0.8417344040000001,-1.9733879840000002,-2.446042147,-2.676445598,0.047433311,-0.191696332,-0.17229827,0.068956485,-0.427227976,-1.256240832,-2.13148291,-1.8152930580000002,-2.054586043,-2.8374982510000004,-2.501217975,-2.8516732210000004,0.750088025,-0.35224161,-14.66709831,-14.92348183,-16.29221439,-14.73180854,-12.662577800000001,-14.725408999999999,-9.232420879,-7.110701665,-14.23288345336914,-18.21510887145996,-14.798401832580566,-15.923893928527832,-13.955766677856445 -2402,2402,L150M,0.09258706900000001,0.179335212,0.112077513,0.091372157,0.09140153300000001,-0.049605820999999994,0.084471135,0.10070300199999999,0.22953557800000002,0.091185106,0.267485317,0.056329446,0.16782557899999997,0.080349082,0.10239523199999999,-0.014499317,0.197302383,1.100080585,2.476287868,-3.1165467189999996,-3.1796852110000002,-2.8438329469999997,-4.543422722,-2.636067726,-2.379724991,-2.88821799,-0.9404472490000001,-6.997097015380859,-9.050981521606445,-5.799050331115723,-6.362880706787109,-6.913352966308594 -2403,2403,L150N,-0.017720253000000002,-0.014225482,-0.014509528,-0.030351361,-2.256755267,0.060836282,0.015712016000000002,-0.051152522,0.21805576100000001,-0.011782754,-0.016668209,-0.030387333,0.001368278,0.072838474,-0.133541195,-1.867483815,-2.6460267180000003,0.496138171,1.2979856779999999,-14.18204029,-15.00603425,-14.426244199999998,-13.98019204,-12.33575796,-15.16197301,-8.138807374,-5.674645896,-10.971918106079102,-16.32479476928711,-9.794208526611328,-14.293174743652344,-14.335137367248535 -2404,2404,L150Q,-0.07553734,-0.062725079,0.013701327,-0.227173863,-1.5523361119999999,-0.003981943,-0.063550274,-0.087524406,-0.0037563229999999998,-0.059548428,-0.065901729,-0.031409603,0.058812257,-0.031108887999999998,-0.42323883799999995,-1.473891804,-1.6307804190000001,0.817772387,1.328862368,-14.08945655,-14.81496547,-14.91342899,-14.50094481,-12.18209534,-14.03584814,-9.229588847999999,-7.110701665,-11.310012817382812,-16.607397079467773,-10.33414077758789,-14.186271667480469,-13.394915580749512 -2405,2405,L150P,-0.065382715,-0.5918797579999999,-1.832835433,-2.193421863,-3.1528743219999997,0.13295653400000002,-0.05167147,-0.079093959,0.066893855,-0.363832692,-0.819926824,-1.7772216019999998,-1.888449263,-1.9606097619999998,-2.426233963,-2.7861584660000003,-3.519590178,2.961349662,1.195106381,-13.95135334,-14.78890691,-16.01038294,-14.10014202,-10.77193285,-14.08540197,-8.052557913,-5.4530760439999995,-12.449378967285156,-18.421470642089844,-10.657164573669434,-13.642561912536621,-14.197090148925781 -2406,2406,L150S,-0.046776632,0.0065802840000000005,0.016289713,0.023886551000000002,-1.7332327109999999,0.07554303700000001,-0.037579605,-0.055973659,0.044787858,0.006563462,0.006597106,0.008949516999999999,0.023629908999999998,0.050579541,-0.00280644,-1.554219363,-1.912246059,0.528071421,1.3099474009999998,-12.07809325,-12.83869256,-12.12662861,-11.19378027,-9.692075134,-14.5392897,-6.961312436,-4.0693790530000005,-10.441717147827148,-14.138668060302734,-7.521382808685303,-10.739309310913086,-11.398563385009766 -2407,2407,L150R,-0.053265797999999996,-1.0217393540000002,-2.230770936,-2.4613900419999997,-3.2023881419999998,0.11422646199999999,-0.020167505,-0.08636409,0.098114714,-0.85882605,-1.184652657,-2.459076155,-2.002465716,-1.96304998,-2.959730103,-2.652719961,-3.752056322,0.242857089,-0.605414424,-14.66356464,-15.05870915,-15.77528696,-14.96910018,-12.94443404,-14.57029287,-9.0262718,-7.110701665,-13.735172271728516,-15.316070556640625,-13.460588455200195,-14.518646240234375,-14.184850692749023 -2408,2408,L150T,-0.049834562,0.010273896,0.037321355,0.018731573999999997,-0.568561937,0.058967847000000004,-0.049840529,-0.049828594000000004,0.08289463,0.021523827000000002,-0.000976036,0.06132052599999999,0.013322183000000001,0.048060425,-0.010597276999999999,-0.432077064,-0.705046809,1.1120257709999999,1.65511589,-10.16093898,-10.46579289,-11.99792701,-10.07658891,-7.478969467000001,-10.78541664,-5.826601027000001,-3.147321718,-9.416354179382324,-12.875707626342773,-5.99606990814209,-7.993864059448242,-10.421935081481934 -2409,2409,L150W,-0.058640560999999994,0.018804504,-0.02076738,0.00017371299999999998,-1.6126777890000001,0.061150674,-0.044170485999999995,-0.07311063599999999,0.126847726,-0.032218605,0.069827613,-0.011952403,-0.029582357000000004,0.02182707,-0.021479644,-1.58580745,-1.6395481280000002,0.540930195,1.309569983,-10.37916801,-12.61706778,-12.43342667,-8.607806931,-9.65004908,-8.587489601,-5.766095277000001,-2.7821227019999997,-9.098100662231445,-14.491044998168945,-9.323761940002441,-11.009377479553223,-11.147441864013672 -2410,2410,L150V,-0.086111033,0.004775975,-0.0040660340000000005,-0.013784925,-0.09274890599999999,-0.013150112,-0.07524776400000001,-0.096974301,0.103177621,-0.010398032,0.019949981999999998,0.046300800999999996,-0.054432869,0.06487095400000001,-0.092440803,-0.073030053,-0.112467759,1.242938643,2.373763752,-5.985536081,-5.131223442,-6.809540763999999,-6.163364365,-3.9884402239999996,-7.83511161,-4.268977272,-1.717242375,-7.131479263305664,-8.930913925170898,-5.026604175567627,-4.393482208251953,-7.7169389724731445 -2411,2411,L150Y,0.026452536000000002,0.001174105,0.024649657000000002,0.035319501,-0.6687882789999999,-0.091565285,-0.022369983,0.075275055,0.12679602199999998,-0.04677414,0.04912235,0.029006319,0.020292993999999998,-0.000630487,0.07126948799999999,-0.62515948,-0.712417077,1.12631369,1.5505431180000002,-10.84543168,-11.993997,-13.3719113,-10.16871259,-9.384828171,-9.307709335,-6.616223794,-3.8876688589999997,-10.158334732055664,-13.426961898803711,-9.11042594909668,-11.27932071685791,-10.030390739440918 -2412,2412,H151A,-0.046477107999999996,0.021157649,-0.020395872,0.015322638000000001,0.03070164,0.031942726,-0.0029893529999999997,-0.089964863,0.0066047319999999994,-0.016497253,0.058812551,-0.062303240999999995,0.021511497,-0.050637469000000004,0.081282745,-0.019153563000000002,0.080556843,1.15077845,2.403569891,-1.5858388669999999,-1.835880821,-1.11686821,-0.8176582029999999,-2.43031926,-1.728467842,-3.4964755380000003,0.8444479220000001,-5.381161689758301,-7.417849540710449,-5.161607265472412,-6.449534893035889,-6.884493350982666 -2413,2413,H151C,-0.045538208,0.025167295,-0.054516722999999996,-0.036545309,-0.143451535,0.042520052,-0.009179281,-0.08189713400000001,-0.011888188999999999,0.014139093,0.036195497,-0.071872483,-0.037160962,-0.062247834,-0.010842784,-0.132103218,-0.154799851,1.605452852,2.414478064,-4.563567526,-4.527917663999999,-4.41438118,-4.26418409,-4.752473061,-4.858881638,-5.1744613,-3.352667046,-5.3521318435668945,-10.03745174407959,-6.43628454208374,-7.701550006866455,-6.911013603210449 -2414,2414,H151E,-0.047776822000000004,0.006297255,-0.033884789,0.033886409,0.044633236,0.06700167,-0.03021653,-0.065337113,-0.045654487,-0.041028821,0.053623330999999996,-0.082410489,0.014640911000000001,-0.023319222999999997,0.091092041,0.018220682,0.07104579,1.173169195,2.582666349,-2.24050645,-2.255801834,-1.6977781140000001,-3.013594978,-2.762445465,-1.472911858,-3.212838432,0.345157791,-6.5324201583862305,-7.227654457092285,-5.602574348449707,-6.577243804931641,-7.917325496673584 -2415,2415,H151D,-0.044039707000000004,0.022865284,-0.06582424099999999,0.008280046999999999,-0.029224302,0.06492058,0.016005791999999998,-0.104085206,0.068952473,-0.018023578999999998,0.063754146,-0.078268978,-0.053379504,-0.0057818769999999995,0.02234197,-0.075783487,0.017334883,1.3347141059999998,2.375770155,-3.470302002,-3.41700042,-2.496059975,-4.205064293,-4.34515802,-2.8882273030000003,-3.396490071,0.04903571599999999,-7.216395378112793,-8.38362979888916,-6.862585544586182,-7.357587814331055,-9.097997665405273 -2416,2416,H151G,-0.080441065,0.028835296,-0.039573646000000004,0.017249979,0.029651278,0.044385369,-0.0067079340000000005,-0.154174195,-0.004901134000000001,0.015216511,0.04245408,-0.055479394,-0.023667898,-0.018065403,0.052565361,0.0013677,0.05793485599999999,1.230666477,2.641543675,-2.948444298,-3.0671355819999997,-2.8744929889999997,-3.137199028,-3.6472197339999997,-2.016174156,-3.6252899789999997,-1.20003284,-5.701385498046875,-8.471075057983398,-5.013879776000977,-7.069431781768799,-7.072467803955078 -2417,2417,H151F,-0.045549962,0.017724714,-0.086559009,-0.031241672,-0.018411069,0.052757940999999996,0.006628898,-0.097728821,0.011482734,-0.046858364000000007,0.08230779099999999,-0.145880984,-0.027237032999999997,-0.09420885300000001,0.031725509,-0.098890761,0.062068624,1.399454659,2.2843237530000002,-5.699448418999999,-5.044653404,-5.797788589,-6.27377948,-4.563595345,-6.817425277999999,-5.9878638010000005,-4.276592733,-8.35494327545166,-10.081347465515137,-7.644154071807861,-8.974981307983398,-8.763862609863281 -2418,2418,H151I,-0.091118696,0.042732436,-0.004307714,0.054077597000000005,0.007014468,-0.009626771,-0.040491866,-0.141745525,-0.0018573620000000002,0.006585955,0.078878916,-0.012686722,0.0040712940000000005,0.010000399,0.098154794,0.001941657,0.012087278,1.4606517890000001,2.864537266,-3.177519615,-3.546555328,-3.824728447,-3.588412224,-2.858729332,-2.069172745,-3.86348977,-1.9206402280000001,-6.753641128540039,-9.669551849365234,-7.212419033050537,-8.345316886901855,-7.810912609100342 -2419,2419,H151K,-0.115419731,0.020234528,-0.065171224,-0.005745355,0.007145896999999999,-0.015184435,-0.062193873,-0.16864558899999998,0.055915981,-0.055918003,0.09638705800000001,-0.073744278,-0.056598169000000004,-0.048055698,0.036564989,-0.028823177999999998,0.043114972,1.3808795530000002,2.5726562790000003,0.01622829,-0.209568008,-0.30559009600000003,-0.810663803,0.45093084,0.9560325159999999,-1.999887147,0.796016994,-2.901870012283325,-5.85952615737915,-3.8400754928588867,-5.36916446685791,-4.216357707977295 -2420,2420,H151M,-0.084675154,0.032402332,-0.03601272,-0.0008947810000000001,0.04515802,0.018803699,0.002492075,-0.17184238300000002,-0.0049213270000000005,-7.780000000000001e-05,0.064882464,-0.028905156,-0.043120284,-0.027030649,0.025241087000000002,-0.0038073609999999996,0.0941234,1.2452271190000002,2.512020517,-4.272683931,-4.512946747,-4.075936508,-4.390445129,-4.570787605,-3.813303665,-4.896618336,-2.977771011,-7.490316390991211,-9.21303939819336,-7.14724588394165,-9.352930068969727,-7.8682780265808105 -2421,2421,H151L,-0.03714882,0.024070078999999998,-0.018514441,0.023054959,-0.024805365,0.060781385,-0.007202656,-0.067094983,0.02129678,0.000404481,0.047735676,-0.045726634,0.008697752,-0.012015828999999999,0.058125747,-0.030168043999999998,-0.019442686,1.329506211,2.632417145,-1.846781851,-2.6581923290000002,-1.5324610140000001,-2.128407913,-1.854939163,-1.059908836,-2.757528375,-1.1084670140000001,-6.17205810546875,-8.173907279968262,-5.7398481369018555,-7.834437847137451,-6.558260440826416 -2422,2422,H151N,-0.04167483,0.111773845,-0.00887768,0.057593869000000006,0.079552158,0.015522741000000001,0.059770730999999994,-0.14312039099999999,-0.025132627,0.023678893,0.199868797,-0.013080231999999999,-0.004675128,0.017106575,0.09808116199999999,0.033374576,0.125729739,1.209489535,2.733143689,-2.263015172,-2.250972794,-2.489696518,-3.5878673169999997,-2.049047302,-0.9374919279999999,-3.4801793739999995,-0.295191553,-5.38020133972168,-5.278790473937988,-5.302894115447998,-6.040377140045166,-6.38800573348999 -2423,2423,H151Q,0.008097306,0.049487545,-0.023534331000000002,0.020552461,0.068242096,0.012247869,0.024699537999999997,-0.008504926,-0.035589159,0.026356982999999997,0.072618106,-0.035769896,-0.011298765,-0.012973296,0.054078217000000005,0.027385938999999998,0.109098253,1.203635836,2.578888789,0.0019400970000000002,0.12589286800000002,0.062662415,-0.164153305,-0.235706337,0.221004845,-2.0399553409999998,0.357678089,-3.4950358867645264,-4.438093185424805,-3.589367389678955,-4.462342739105225,-4.431765556335449 -2424,2424,H151P,-0.10883213900000001,-0.021637302,-0.052757775,-1.106333963,-2.286537924,0.074657818,-0.050747093,-0.166917185,-0.020200868,-0.016304524,-0.02697008,-0.069524175,-0.035991374,-0.838893923,-1.373774003,-2.011578778,-2.561497069,2.143913215,1.526947865,-5.068095193,-4.291822182,-5.608892792000001,-4.753143005,-6.059317397999999,-4.627300591,-5.164181419,-2.9374735889999997,-8.91817855834961,-13.451517105102539,-6.990701198577881,-10.437725067138672,-10.505026817321777 -2425,2425,H151S,-0.038089448,0.026742527000000002,-0.03233603,-0.009772832,0.010206805,-0.013619527,0.011139602,-0.087318497,-0.00040807,0.001291514,0.052193539000000004,-0.042432608,-0.022239452000000003,-0.028454668,0.008909005,-0.014489888999999999,0.034903499,1.170104237,2.370551146,-2.427499944,-2.709459015,-2.572771545,-2.807108597,-2.464512917,-1.583647644,-3.764147701,-0.528210525,-5.555468559265137,-7.715928077697754,-5.03769588470459,-5.99866247177124,-5.995420932769775 -2426,2426,H151R,-0.031582805,0.013201901,-0.03382406,0.00759869,0.02308135,0.026862902999999997,0.005308768,-0.068474378,-0.039748774,-0.01149753,0.037901331,-0.050839445,-0.016808675,-0.020141915,0.035339294,0.010763435,0.035399264,1.155493763,2.649198214,4.344642407,4.331341728,4.692338112,5.363595131,3.47327803,3.862659035,-0.198878904,2.545079743,2.536712646484375,-1.16168212890625,1.7105417251586914,-0.40237855911254883,0.36519289016723633 -2427,2427,H151T,-0.07090395099999999,0.023371469,-0.045426524,0.028249187999999998,0.016665056,0.019913848,-0.009841546,-0.131966355,0.028475753,-0.004828746,0.051571683,-0.056941548,-0.033911500000000004,-0.017645631000000002,0.074144006,-0.009570299,0.04290041,1.27048636,2.589348045,-2.731234155,-2.628215569,-2.418522293,-2.816511993,-3.382757095,-2.410163826,-3.317627615,-0.6360176679999999,-5.62148380279541,-7.744036674499512,-5.556440353393555,-6.782975196838379,-6.579737186431885 -2428,2428,H151W,-0.10375080199999999,0.020314651,-0.043713862,-0.002036515,-0.034528765,0.018080151000000003,-0.066175233,-0.141326371,0.077846187,0.011673413999999998,0.028955887000000003,-0.050398819000000004,-0.037028905,-0.023713847000000003,0.019640816999999998,-0.017600803,-0.051456725999999994,1.299376244,2.5596218619999997,-4.98897953,-4.91882827,-4.922684837,-5.326031517,-4.991850777,-4.7855022510000005,-6.305067339,-4.257562887,-6.731389045715332,-10.64813232421875,-6.280178546905518,-6.3187947273254395,-7.61173677444458 -2429,2429,H151V,-0.053295484000000004,0.00728024,-0.041171397,0.009840624000000001,0.001629947,0.024982499999999998,-0.039419472000000004,-0.067171495,0.024944842999999998,-0.045989575,0.060550055,-0.08687916,0.004536367,-0.031761713999999996,0.051442960999999995,-0.052323575,0.055583469,1.304107946,2.425258235,-2.983877829,-3.3528355789999997,-3.5123106689999997,-2.634823601,-3.164674255,-2.254745041,-4.354236141,-1.409153789,-6.35429573059082,-9.570415496826172,-7.064576625823975,-7.702491283416748,-8.316527366638184 -2430,2430,H151Y,-0.085886227,0.019180636,-0.057377683,0.002261466,0.007816278000000001,0.039328978,-0.029727088999999998,-0.142045364,0.012390965,0.025417258999999998,0.012944012,-0.059040362,-0.055715003,-0.015163941,0.019686873,-0.020771071999999998,0.036403628,1.39417163,2.600260542,-5.068441486,-5.341093628,-5.749372527999999,-5.767723907000001,-3.9787299039999997,-4.50528746,-5.564242997999999,-3.272516818,-7.555477142333984,-8.50910472869873,-6.7265400886535645,-7.359051704406738,-6.52020788192749 -2431,2431,N152A,-0.011433482,-0.04994268,-0.022527537,0.010882838,-0.039471637999999996,-0.043359589000000004,-0.013351196000000001,-0.009515767,0.011803313000000001,-0.020344468,-0.079540892,0.007183927,-0.052239,0.014283019,0.007482656,-0.00504614,-0.073897135,1.543610422,3.106887046,0.768850725,0.39561691299999996,-0.024943427999999997,2.089611641,1.223895515,0.160072983,-2.1336775340000003,1.565206209,-2.472280740737915,-3.2002081871032715,-2.1991095542907715,-1.8852767944335938,-3.0586256980895996 -2432,2432,N152C,0.015336401999999999,-0.034951536,0.003714497,0.043710741,-0.154368375,-0.035345216,0.022171002000000002,0.008501801,-0.0034580270000000002,-0.020414465,-0.049488606,0.040376736,-0.032947743,0.02746781,0.05995367099999999,-0.09915880099999999,-0.20957794800000001,1.3695411290000001,2.402694163,-3.849361131,-3.6189486239999997,-4.719303406,-3.1568600539999996,-3.477322762,-4.274370811,-6.1579855729999995,-3.7305060739999996,-7.692262172698975,-9.137469291687012,-8.343904495239258,-8.360123634338379,-9.10167121887207 -2433,2433,N152E,-0.033090503,-0.062174784000000004,-0.014990673999999999,-0.056213158,-0.011654538999999998,-0.124114048,-0.034000033,-0.032180972,0.073786214,0.13939483,-0.263744397,0.099498188,-0.129479536,0.10710552400000001,-0.21953183899999998,0.035778282,-0.05908736,1.140601244,2.8972879000000002,0.65273307,1.161050987,0.217034134,1.165320793,1.4308720469999998,-0.71061261,-2.7950094780000003,1.83743699,-3.64026141166687,-3.3079538345336914,-2.735954999923706,-3.0203804969787598,-4.538928985595703 -2434,2434,N152D,0.054758835,-0.021588859,-0.008413435,0.049488544,-0.030300907999999998,-0.049508684000000004,0.068661483,0.040856187,-0.038500776,0.042091355999999996,-0.085269073,0.012942122,-0.029768991,0.054255315,0.044721772,-0.00028289200000000003,-0.060318924,1.246123487,2.69232746,0.168927968,0.495791855,-0.647542694,0.38547754700000003,1.5538800659999998,-0.9429669340000001,-2.3323221419999998,1.216213012,-3.473642587661743,-2.9114673137664795,-2.5138533115386963,-3.3256142139434814,-4.119909763336182 -2435,2435,N152G,-0.027611339,-0.053810582999999995,-0.033734201,-0.011688862,-0.066780817,-0.02528902,-0.015056561000000001,-0.040166116,0.05281695,-0.018405658000000002,-0.08921550800000001,-0.008719329,-0.058749072,-0.017047863,-0.006329861,-0.041435449,-0.092126185,1.178655953,2.382238516,0.7683725809999999,0.304195663,1.1831388170000001,1.2090421679999999,1.248031105,-0.102544846,-1.522460535,1.25857957,-2.1298513412475586,-2.3183932304382324,-1.9806897640228271,-2.297335624694824,-2.4162817001342773 -2436,2436,N152F,-0.069340403,-0.063699459,-0.020861878,-0.000530987,-0.108405949,-0.004646525,-0.074917873,-0.06376293200000001,0.001342488,-0.043669828,-0.083729089,0.002588175,-0.044311931,-0.012031087,0.010969113999999999,-0.090938665,-0.125873232,1.808125749,2.84446623,-2.806405893,-3.024840897,-3.307155266,-2.054990761,-2.186311089,-3.458731453,-4.474009247,-2.455259395,-7.189205169677734,-8.940834045410156,-8.340251922607422,-8.090354919433594,-6.942511558532715 -2437,2437,N152I,0.030775419,0.012550933,-0.020116009,0.029934289,-0.079239517,-0.013439395,0.030858986,0.030691852000000002,0.006984069,0.020539744,0.004562121,-0.028855479,-0.011376539,0.012476103,0.047392474000000004,-0.067062023,-0.09141701099999999,1.382262972,2.480259362,-3.087599748,-3.1140351330000002,-3.7666657710000004,-1.9789742430000001,-2.7979511180000003,-3.780372475,-5.141970217,-2.588873713,-6.867576599121094,-8.563502311706543,-7.350566387176514,-6.82839298248291,-7.408720016479492 -2438,2438,N152H,0.045923381,-0.001280085,0.004123616,0.029810105,-0.024670175,-0.050381217,0.044559213,0.047287549000000005,0.019882567,0.008278591,-0.010838761,0.010343187,-0.002095956,0.026832796000000003,0.032787414,-0.007348808,-0.041991542,1.222447558,2.570798611,-1.030588254,-1.248663322,-1.69190377,-0.17603438600000001,-0.277528732,-1.758811058,-3.288689088,-1.350892114,-5.119627952575684,-5.424233436584473,-5.258571624755859,-5.279306411743164,-4.3346734046936035 -2439,2439,N152K,0.003158785,0.013774008999999999,0.008786061,0.051147214,-0.009286896999999999,-0.029543416,0.017465254,-0.011147685,0.010718233999999998,0.042928201,-0.015380183,0.091377963,-0.073805842,0.08538343,0.016910997,0.02493349,-0.043507283,1.096146598,2.6734270319999998,1.7153535640000002,1.620443321,1.3737128980000002,2.3932113719999997,1.749741745,1.439658485,-0.214358098,1.170426945,-3.1971893310546875,-4.028428554534912,-3.3360161781311035,-3.189534902572632,-3.2655787467956543 -2440,2440,N152M,0.044283533,-0.030662073999999997,0.024355115,0.069174231,0.054737747999999996,-0.03740111,0.050431671,0.038135395,0.144009991,-0.056073295,-0.005250851999999999,0.024382131,0.024328098,0.032262127,0.106086335,0.026008329,0.08346716700000001,1.0430483990000001,2.559148394,-2.381776381,-2.493438545,-2.984979553,-1.085790207,-1.8693703380000002,-3.475303261,-4.871930773,-1.957744891,-6.514927864074707,-7.7350687980651855,-6.904633522033691,-6.532444000244141,-6.472003936767578 -2441,2441,N152L,0.013555494,-0.023193484,0.004188682,0.04564749,-0.023505812,-0.028525767,0.026038891,0.001072097,0.039961961000000004,0.027063992999999998,-0.07345096,0.060467945,-0.052090582,0.048321959000000005,0.04297302099999999,-0.019168137,-0.027843487000000004,1.148125972,2.50576595,-1.35959268,-1.201248047,-2.26440416,0.038652626,-0.600534775,-2.770429047,-3.2987885439999998,-0.828496942,-5.4736552238464355,-6.966689109802246,-5.907068252563477,-5.977931022644043,-5.852396488189697 -2442,2442,N152Q,-0.042668194000000007,-0.052723915,-0.024074885,0.023678823999999998,-0.018047743999999998,-0.027222355,-0.044720729,-0.040615658,0.084737964,-0.017646029,-0.087801801,0.036199114,-0.084348884,0.057817165,-0.010459518000000001,-0.024098985,-0.011996503,1.1219573870000001,2.500446185,1.468100661,2.15658979,1.116757072,2.12848365,1.2436436309999999,0.69502916,-1.300696584,0.870261335,-3.2764811515808105,-3.6124396324157715,-2.972071409225464,-3.0215535163879395,-3.8398118019104004 -2443,2443,N152P,-0.017327548999999998,-0.013641998,-0.028842046,-0.811814577,-2.12322271,0.031354982999999996,0.026861332,-0.06151643,0.024250056000000002,0.003780999,-0.031064995,-0.012119708,-0.045564384000000006,-0.33849241799999996,-1.285136736,-1.902535715,-2.343909704,1.466137834,1.363625619,-5.075810951,-5.29488269,-5.314871552,-4.264208733,-4.653109894,-5.851981887999999,-7.4333293639999996,-6.615121461,-7.170936107635498,-8.323729515075684,-6.411283016204834,-7.275806427001953,-8.652193069458008 -2444,2444,N152S,0.020134507,-0.014112863,-0.013367666,0.027804474,-0.015036708999999999,-0.013167468,0.049892985,-0.009623971,0.014690271999999999,-0.013324997,-0.014900728,0.0047511129999999995,-0.031486444,0.013550214,0.042058733,-0.00953398,-0.020539437,1.099033345,2.603512733,1.931280203,1.220965279,1.990486961,2.690310287,2.1436993330000003,1.610939156,-1.4552245519999998,2.4531232309999997,-0.9967254996299744,-2.1097168922424316,-1.0517125129699707,-0.7530312538146973,-1.6205188035964966 -2445,2445,N152R,-0.0037177720000000003,-0.023367294,-0.018911358,0.026811125,0.021453871,-0.016292373,0.001525304,-0.008960847,-0.004586294,-0.013420142,-0.033314445,-0.000501654,-0.037321062,0.011024178,0.042598072,0.002115921,0.040791821,1.1775332090000001,2.56891234,0.98794026,1.7498448030000002,-0.038460495,2.0215810469999997,1.561235016,-0.354499069,-2.5448919169999997,1.2293010229999999,-3.130171537399292,-4.607046604156494,-3.535470724105835,-3.3268473148345947,-3.6500439643859863 -2446,2446,N152T,-0.020735158,-0.023301345,-0.027087315,0.02854487,-0.035577057,-0.005014857,0.00903169,-0.050502005999999995,-0.044922233,0.018373623999999998,-0.06497631400000001,0.004267882,-0.058442510999999996,0.043157804,0.013931936,-0.032509479,-0.038644634,1.08978692,2.3610760490000002,0.645357855,0.8170365909999999,0.21410801699999998,1.9276523209999998,0.711049278,-0.443056931,-2.262719106,0.866706216,-3.2643213272094727,-3.9588677883148193,-3.3921611309051514,-2.4271817207336426,-3.4183244705200195 -2447,2447,N152W,0.031493919,0.014761498999999999,0.018358901,0.011484901,-0.079932065,-0.004126793,0.034248874,0.028738964,0.058657192999999996,0.036962453,-0.007439455,-0.015728729,0.05244653,0.015170952,0.007798849,-0.06791575700000001,-0.09194837300000001,1.443425681,2.567130944,-3.225853453,-3.2218274310000004,-3.720396935,-2.719429031,-2.519909088,-3.947704781,-5.0712110269999995,-2.697781782,-8.176177024841309,-10.406622886657715,-8.265813827514648,-9.467206954956055,-8.652403831481934 -2448,2448,N152V,0.020876126000000002,-0.038652517000000004,-0.014410437,0.025214737999999997,-0.04207795,-0.047828653,0.019783987,0.021968263999999998,0.01614578,-0.035985595,-0.041319439,-0.018656864,-0.01016401,0.00841658,0.042012895,-0.064068489,-0.02008741,1.321427578,2.414619047,-2.657493413,-2.9007463760000003,-3.221209946,-1.407447266,-2.2718316730000003,-3.4862318039999995,-4.745565372,-2.0909427519999997,-5.826479434967041,-7.428424835205078,-6.1448655128479,-5.408607482910156,-6.409187316894531 -2449,2449,N152Y,0.0017425129999999998,-0.088085441,-0.039997519,-0.005133493,-0.111851337,-0.10883629,-0.020533333,0.024018359,0.056415895,-0.019722889,-0.15644799199999998,-0.028904932999999997,-0.051090104000000004,0.013821521000000002,-0.024088506000000003,-0.070463882,-0.15323879199999998,1.448219973,2.5538123269999997,-4.094043797,-4.05106395,-4.7394282610000005,-3.596618172,-3.6128402860000004,-4.4702683180000005,-6.50670837,-4.0163065730000005,-7.7967047691345215,-8.955988883972168,-7.9824700355529785,-8.394505500793457,-6.544450759887695 -2450,2450,M153A,-0.000893157,-0.04853888,-0.024352192,-0.01493279,-0.068678108,0.043481003,0.015309604,-0.017095917,0.013322961000000001,-0.09293362599999999,-0.0041441329999999995,-0.074674269,0.025969886,-0.041686672,0.011821093000000001,-0.120122695,-0.017233521,1.4081125909999999,2.282057485,0.21192924300000002,0.437196915,-0.090135231,0.575755928,-0.23217009,0.368998695,-1.746891411,-0.023798938999999998,-4.306514263153076,-5.274127006530762,-4.947875022888184,-6.86966609954834,-5.036584377288818 -2451,2451,M153C,0.015455917,-0.074472176,-0.02530344,-0.003911755,-0.06451559700000001,0.043405187000000005,0.042595897,-0.011684064,0.01242164,-0.106103374,-0.042840977,-0.070646215,0.020039335,-0.031979185,0.024155676,-0.107687097,-0.021344096,1.568085565,2.44574677,-3.1864876939999998,-2.263960205,-2.9786208189999996,-2.346251724,-3.9747441180000003,-4.368861603,-4.6490666560000005,-2.505589322,-4.392425537109375,-7.950666904449463,-5.950706481933594,-8.982091903686523,-6.012645244598389 -2452,2452,M153E,-0.045572932999999996,-0.07537656200000001,-0.079731778,-0.057863318,-1.375037549,0.0033391590000000004,-0.012520982,-0.07862488299999999,0.029383778,-0.08652353300000001,-0.064229591,-0.105541976,-0.053921579000000004,-0.070869834,-0.044856800999999995,-1.299176098,-1.450899,0.973432174,1.3615191530000001,-3.334168483,-3.4092448810000002,-2.685111885,-2.718372231,-3.225838646,-4.632274773,-4.985266744,-2.71249938,-5.443647861480713,-7.027054309844971,-7.224112033843994,-9.209877967834473,-7.192798137664795 -2453,2453,M153D,-0.017972121,-0.12088988099999999,-0.034838121,-1.314663933,-3.100132561,0.029438235,0.035049322,-0.07099356400000001,0.015850057,-0.116235209,-0.125544553,-0.09882889800000001,0.029152657000000002,-1.020945203,-1.608382662,-2.755195666,-3.445069456,1.190455422,0.849291638,-5.0973537339999995,-4.35689151,-4.215814331,-4.369893982,-6.259194762999999,-6.284974083,-6.465352212000001,-4.622148813,-8.076952934265137,-9.649099349975586,-8.736345291137695,-11.515588760375977,-9.166346549987793 -2454,2454,M153G,0.00011674799999999999,-0.070426135,-0.065525482,-0.039725743,-0.718774831,0.043237013,0.044669713,-0.044436217,0.061309338,-0.110951718,-0.029900551,-0.110731119,-0.020319845,-0.078920698,-0.000530787,-0.6061763720000001,-0.8313732890000001,1.4066612040000002,1.7004063130000002,-3.8582785339999996,-3.313970657,-3.250262222,-3.220343544,-5.242351799,-4.264464447,-5.205583121,-2.46660317,-6.286167621612549,-9.211604118347168,-8.578540802001953,-10.79827880859375,-8.222825050354004 -2455,2455,M153F,0.031660399,-0.032419965,-0.044628695999999995,-0.01831842,-0.20109806300000002,0.004587052,0.078264185,-0.014943386999999999,-0.040803012,-0.056522775,-0.008317155,-0.072701204,-0.016556187,-0.031902299,-0.004734541,-0.22128372,-0.18091240600000003,1.4531365019999998,2.105537494,-3.165231651,-3.6596690219999997,-2.100636566,-1.939097076,-4.7180811160000005,-3.408674477,-3.383627142,-0.8796904320000001,-4.866546154022217,-6.232311725616455,-4.914139747619629,-6.434433937072754,-5.45090913772583 -2456,2456,M153I,-0.02279005,-0.069966051,-0.05886631,-0.025849927999999998,-0.023306261,0.010288365,-0.00036024099999999997,-0.045219857999999995,0.063780595,-0.075334311,-0.064597791,-0.08592738400000001,-0.031805236,-0.023915812,-0.027784044,-0.032520619,-0.014091903000000001,1.3673579130000002,2.482879168,2.582267645,3.1331363910000003,2.853251694,2.396836319,2.380410156,2.147703667,-1.27754249,1.526494021,-2.309136390686035,-1.139352798461914,-0.8911390900611877,-1.4885258674621582,-1.9188112020492554 -2457,2457,M153H,-0.030460322,-0.06442835200000001,-0.064770973,-0.051160113,-0.558468368,0.012488744,0.021857293,-0.082777937,0.013788284,-0.078836705,-0.050019997999999996,-0.043050362,-0.08649158300000001,-0.042793229,-0.059526997000000005,-0.42259626899999997,-0.6943404670000001,1.266592186,1.714353044,-2.50647159,-0.550963654,-1.5793248519999998,-1.2419989470000001,-3.914439743,-5.245630753,-3.932681324,-0.624151115,-2.8697009086608887,-6.2435197830200195,-6.593573570251465,-8.104496002197266,-5.694812774658203 -2458,2458,M153K,0.000344509,-0.063911195,-0.046524015999999994,-8.82e-05,-1.354327293,0.016966521000000002,0.060000798,-0.05931178,0.09397558,-0.076633007,-0.051189383,-0.054288727,-0.038759305,0.0056642969999999996,-0.005840665,-1.151225158,-1.557429427,0.885738327,1.3626752930000001,-2.196114149,-0.935360588,-2.324760757,-1.56796151,-1.170633324,-4.981854568,-4.456458958,-0.435720121,-4.142889976501465,-6.080564498901367,-7.940382480621338,-9.447653770446777,-5.6680474281311035 -2459,2459,M153L,0.021723107000000002,-0.048140757,-0.042822708,-0.018348258,-0.047138285,-0.002502523,0.041060121,0.0023860920000000002,-0.027541573,-0.082715873,-0.013565641000000002,-0.09043751900000001,0.004792104,-0.036401733,-0.000294783,-0.091721595,-0.002554974,1.414371733,2.342971976,0.829538179,0.194063995,1.34887043,1.328326263,0.632747253,0.643682953,-2.055258549,2.3552972569999997,-1.689436435699463,-1.9955997467041016,-1.4415979385375977,-1.8863695859909058,-1.457707405090332 -2460,2460,M153N,-0.059078343,-0.100293009,-0.051161989000000005,-0.046712507,-0.26143853300000003,0.033236719,-0.030480956,-0.08767572900000001,0.008509433,-0.101656436,-0.09892958199999999,-0.036927277,-0.0653967,-0.03609188,-0.057333133,-0.24538801699999999,-0.277489048,1.3653149269999998,1.992304153,-0.7760457820000001,0.470534561,-0.19487994399999997,-0.589908401,-0.8645747909999999,-2.701400337,-3.2277057630000003,-0.625274569,-2.990952730178833,-5.754917144775391,-6.078815460205078,-7.52283239364624,-5.718543529510498 -2461,2461,M153Q,-0.0013257170000000001,-0.029950998,-0.040994471,0.00935391,-0.266883514,-0.003264083,0.022920625,-0.025572058999999998,0.01615808,-0.030272777999999997,-0.029629217000000003,-0.044988329,-0.037000612999999995,0.009399926999999999,0.009307892,-0.24108940899999998,-0.292677619,1.287016148,1.9182968619999998,-1.5684473280000002,-1.309676872,-1.7117624740000001,-0.91107859,-0.772566887,-3.137151817,-3.494837563,-0.711963173,-2.601205348968506,-4.975444793701172,-5.225790023803711,-6.527070045471191,-4.5012664794921875 -2462,2462,M153P,-0.045457594000000004,-0.5864100839999999,-1.689459473,-2.140285318,-2.742925642,0.067042502,0.012818969,-0.103734157,0.031219079,-0.36559740799999996,-0.8072227590000001,-1.671050111,-1.7078688340000001,-2.11601345,-2.164557186,-2.737365795,-2.748485488,2.719060063,0.964372197,-5.153808401,-4.427905685,-5.026608253,-4.218106033,-6.119202262999999,-5.977219772000001,-6.6298604039999995,-4.9961512,-10.3682861328125,-11.616642951965332,-10.268392562866211,-12.865425109863281,-9.751328468322754 -2463,2463,M153S,-0.003965683,-0.065935489,-0.039175656,-0.032096354,-0.11301312699999999,0.020120345,0.036870812,-0.044802177,0.010467666,-0.097969296,-0.033901682,-0.0646766,-0.013674711,-0.031692198,-0.03250051,-0.11746129300000001,-0.108564961,1.381479289,2.282366327,0.6655457610000001,1.37475576,0.477734528,0.79950087,0.667361282,0.008376366,-2.363289409,-1.2466061290000001,-4.4185943603515625,-5.847937107086182,-6.178819179534912,-7.791556358337402,-6.1047773361206055 -2464,2464,M153R,-0.031284621,-0.08109103599999999,-0.052212340999999995,-0.019139454,-1.312866025,0.040285937,0.01190677,-0.07447601200000001,0.008397863,-0.08439371300000001,-0.077788358,-0.073031365,-0.031393317000000004,-0.037402242999999995,-0.000876664,-1.125351386,-1.5003806640000001,0.819115143,1.35732959,-3.684900705,-2.412994217,-3.313148895,-2.2555914,-3.4791816019999997,-6.96358741,-4.428052127,-1.56020962,-4.5980753898620605,-7.874314785003662,-7.738760471343994,-8.534811973571777,-6.6360015869140625 -2465,2465,M153T,-0.0036354459999999996,-0.02968158,-0.033427214,-0.012525733999999998,-0.079235997,0.042771225,0.019113598,-0.02638449,0.014957648,-0.06848711099999999,0.009123952,-0.046797418,-0.020057009,-0.038788502,0.013737033999999999,-0.12326215900000001,-0.035209834,1.310114585,2.176296874,2.763943616,3.3077445219999997,1.596822144,3.209587875,3.24173365,2.4638298869999997,-0.9479325559999999,-0.6010921379999999,-4.303805828094482,-4.537744998931885,-5.009881019592285,-7.0559611320495605,-4.886429786682129 -2466,2466,M153W,0.052658416,-0.067811038,-0.039329866,-0.0062506919999999995,-0.063727216,-0.0032316259999999996,0.072304735,0.033012096,-0.032091377000000004,-0.124515225,-0.011106851000000001,-0.11564716300000001,0.036987432,-0.046808665,0.034307281,-0.143930724,0.016476293,1.534922162,2.301276998,-4.119347665,-2.434812645,-3.195022751,-2.828325371,-6.667254112,-5.471323448,-4.872816781,0.352898765,-6.24138069152832,-7.602640628814697,-7.086755275726318,-9.755254745483398,-8.611445426940918 -2467,2467,M153V,0.038254988,-0.066628092,-0.053315928,-0.011454778999999998,-0.099218971,0.004970502,0.061975247000000004,0.014534728,0.004978939,-0.108258414,-0.024997769,-0.088137456,-0.0184944,-0.058090225999999995,0.035180668,-0.119767237,-0.07867070400000001,1.4629270730000001,2.306117247,-0.44197549700000005,-0.425092422,-0.55407206,0.249824173,-1.239437469,-0.241099709,-2.719991605,-0.399499941,-3.7547125816345215,-4.117485046386719,-3.8196890354156494,-4.994627475738525,-4.381996154785156 -2468,2468,M153Y,0.007096401,-0.109894964,-0.063498895,-0.035205286,-1.0359273359999999,0.010788698999999999,0.05474992,-0.040557117999999996,0.022754851,-0.146001897,-0.07378803,-0.09367465300000001,-0.033323136,-0.044880357999999995,-0.025530213,-0.76275478,-1.309099891,1.01803052,1.4617097559999999,-4.124407455,-2.3706070180000003,-2.9218892210000003,-2.8653538210000002,-5.803723366,-6.660463852,-4.632548685,-1.209919585,-4.800498008728027,-7.195099830627441,-6.650792121887207,-8.79151725769043,-6.3319478034973145 -2469,2469,G154A,-0.069519442,-0.014709345,-0.025238107000000003,-0.027580141000000002,-1.237814556,-0.008313525,-0.053914672999999996,-0.08512421,-0.012238958999999999,0.015340573,-0.044759263,0.010110326,-0.06058654,0.000193681,-0.055353963,-0.98456598,-1.491063131,0.638010402,1.348888865,-6.699757701,-6.957807602000001,-6.17841069,-5.970554924,-6.608040634,-7.783974655,-7.070465463,-4.605993106000001,-8.880515098571777,-8.500117301940918,-9.940266609191895,-8.840819358825684,-6.890017032623291 -2470,2470,G154C,0.061699138,0.030642077,0.028610204,0.011641261000000002,-1.748269181,0.072641281,0.08388053200000001,0.039517743,-0.062367747,-0.006077608000000001,0.06736176099999999,-0.072748845,0.12996925199999998,-0.068343878,0.09162639999999998,-1.594745223,-1.9017931380000002,0.897040265,1.330623285,-10.67275105,-10.64373613,-10.65413329,-9.998270927,-10.34248991,-11.725125,-10.23801718,-9.799455849,-11.2179536819458,-11.347265243530273,-13.209833145141602,-11.851530075073242,-9.812764167785645 -2471,2471,G154E,-0.030818934,-0.008143799,-0.012085321999999999,-0.023197002,-0.123728146,-0.007812686999999999,-0.013168187,-0.048469680999999994,0.004011315,0.042298817999999995,-0.058586415999999995,-0.01001445,-0.014156193000000001,0.038065057,-0.08445906,-0.091883591,-0.155572701,1.165170396,2.280433979,-6.282221382,-6.694281448,-6.303623459,-5.689124382,-6.076457695,-6.647619926,-7.424419403,-4.709355358,-7.764777183532715,-7.148752212524414,-8.727270126342773,-7.776424407958984,-5.214480400085449 -2472,2472,G154D,0.028673993,0.029727701000000002,0.06889425099999999,-0.0035245259999999996,-0.095326544,-0.018887621,0.009609884,0.047738101,0.062725365,0.029816371,0.02963903,0.004663378,0.133125123,-0.015973317,0.008924266,-0.07826896900000001,-0.112384118,1.37018417,2.384313874,-4.050534453,-3.836264709,-4.300890121,-3.9506298369999997,-3.816650764,-4.3482368319999996,-4.2033275119999995,-3.7532631910000003,-6.230581760406494,-6.509778022766113,-7.981454372406006,-6.7973432540893555,-3.549105167388916 -2473,2473,G154F,-0.126024532,-0.013778468,-0.019319133,-1.251859222,-2.091244835,0.04696338,-0.113748899,-0.138300165,0.067680395,0.009959789,-0.037516724,-0.010243381999999999,-0.028394884,-0.7582278920000001,-1.745490552,-2.3373581480000003,-1.8451315209999999,0.766748545,0.7910421240000001,-10.98741669,-11.11834149,-10.31445856,-9.640827599,-10.55477,-13.308685800000001,-9.160623625,-7.332861106,-11.356775283813477,-13.140779495239258,-13.631464004516602,-13.09553337097168,-11.068232536315918 -2474,2474,G154I,-0.070364444,-0.004059375,-1.00798015,-2.035501323,-2.6520505,0.049201274,-0.017330149,-0.12339873900000001,-0.189444115,-0.0031536909999999997,-0.004965058,-0.616295215,-1.399665084,-1.475491888,-2.595510758,-2.419893036,-2.884207963,2.3835124469999998,1.318876642,-9.951609966,-10.59664423,-9.216638466000001,-8.706580681,-9.356460579,-11.88172587,-8.440169982,-5.879278424,-12.016550064086914,-13.329885482788086,-12.372900009155273,-12.663921356201172,-12.900341033935547 -2475,2475,G154H,-0.07477357400000001,-0.045542659000000006,-0.035083726,-0.032815073,-0.947665442,0.070243395,-0.04617320900000001,-0.10337393800000001,-0.025136331,0.0015584120000000001,-0.09264373,-0.069752551,-0.00041490099999999996,-0.027713879,-0.037916266000000004,-0.65467167,-1.2406592140000001,0.7915633540000001,1.4189854469999998,-7.105425505,-7.775099487,-7.016882172000001,-5.857788467000001,-6.436165871,-8.441191528,-7.172455042,-4.949104558,-9.21881103515625,-9.213174819946289,-10.61080265045166,-9.29521656036377,-5.316234588623047 -2476,2476,G154K,-0.058742891,0.02000366,-0.047415079000000006,-0.05681420400000001,-1.2103183640000001,0.060809797,-0.008873522,-0.108612259,0.11546301199999999,0.002450187,0.037557132,0.01440133,-0.109231488,0.000478917,-0.11410732400000001,-1.05607221,-1.3645645180000001,0.627515581,1.344324305,-5.645068147000001,-7.2138809429999995,-4.736698204,-3.859962326,-6.100290604,-6.3145086589999995,-6.373937817000001,-3.99748434,-8.783774375915527,-9.19805908203125,-9.786247253417969,-8.168924331665039,-5.709674835205078 -2477,2477,G154M,-0.039382187,0.11502716199999999,0.045672845999999996,-0.129232834,-2.1232713480000003,-0.007799355,-0.054053493,-0.02471088,-0.019291095,0.140708572,0.08934575199999999,0.046810280999999995,0.04453541,0.030206096,-0.288671764,-1.699524887,-2.547017809,0.6763988470000001,1.309820897,-10.52694867,-10.9298212,-10.24547222,-9.66501725,-9.640929291,-12.1535034,-9.138233117999999,-7.258488053,-12.444113731384277,-12.597929000854492,-13.329964637756348,-12.516695976257324,-11.486541748046875 -2478,2478,G154L,-0.056807799000000006,0.026581221000000002,0.000236938,-0.924058356,-1.8288068819999999,0.038265837999999996,-0.03520246,-0.078413138,-0.020302824,0.021261897000000002,0.031900543999999996,-0.086890767,0.08736464199999999,-0.41032844799999996,-1.4377882640000001,-1.9179268369999998,-1.7396869259999999,1.615314093,1.3897826030000002,-10.38756556,-10.76138893,-10.04543601,-9.787281265,-9.702346558,-11.64137503,-8.974184228,-6.70808671,-11.641105651855469,-11.645502090454102,-12.469353675842285,-12.081624984741211,-11.081106185913086 -2479,2479,G154N,0.037178341000000004,0.057117967,0.043187729,-0.025664267999999997,-0.235432728,0.043901895999999996,0.009182891,0.06517379,-0.01424616,0.031377469,0.082858464,0.01828014,0.068095318,-0.022835815,-0.02849272,-0.126653285,-0.344212171,1.310563981,2.1667946209999998,-5.402220216,-5.988703812000001,-4.882593849,-4.824374298,-5.358210495,-5.957218628,-6.313006516000001,-3.9358401819999997,-7.297295093536377,-8.062111854553223,-8.945184707641602,-6.940614700317383,-4.016085147857666 -2480,2480,G154Q,-0.04880471,-0.011037841000000001,-0.020479156999999998,-0.06745567,-0.544538125,-0.000283455,-0.049663439000000004,-0.04794598,-0.050430040999999995,0.005700780999999999,-0.027776462999999998,-0.0019553120000000003,-0.039003002,-0.049079042999999996,-0.08583229699999999,-0.436592669,-0.65248358,1.3186107009999999,1.763316696,-6.921066617999999,-7.915036606,-6.447889732,-5.799887093,-6.45945224,-7.983067421,-6.906009397999999,-4.878748221,-8.746725082397461,-8.433253288269043,-9.513299942016602,-7.995550155639648,-5.155770301818848 -2481,2481,G154P,-0.064134605,-0.017827902,-0.000721582,-1.128028785,-2.117260163,0.041383855,-0.029303851000000002,-0.098965358,-0.0061409509999999995,-0.024102967000000003,-0.011552837,-0.02477055,0.023327387,-0.645319526,-1.610738043,-1.817246556,-2.417273769,1.9822679980000002,1.533326688,-8.871445451,-9.194732903,-8.282525299,-8.028753304,-8.425364532,-10.42585122,-8.238064256,-5.758034822000001,-12.26290512084961,-12.624433517456055,-12.989985466003418,-12.962779998779297,-11.453214645385742 -2482,2482,G154S,-0.02969886,0.040798173,0.011812035,-0.042061182999999995,-0.952716773,0.027383652999999997,-0.002065135,-0.057332585,0.060180357999999996,0.024324271,0.057272074000000006,-0.015292954,0.038917024,-0.040315154,-0.043807211,-0.737836222,-1.1675973240000002,0.92163243,1.42205504,-6.86839415,-7.511909697999999,-6.646678291000001,-6.1553453220000005,-6.501949553999999,-7.526087883,-6.557071093999999,-4.960697881000001,-8.236323356628418,-8.566596031188965,-9.690439224243164,-7.998924732208252,-5.937509059906006 -2483,2483,G154R,-0.019074487,-0.007897897,-0.004886792,-0.007619483000000001,-1.558836255,0.024284791,0.006156223000000001,-0.044305196,-0.034458644,0.002096008,-0.017891801000000002,-0.029708201,0.019934618,0.033642562,-0.048881527,-1.407021784,-1.710650726,0.484834256,1.313717185,-6.502336949,-7.334469055,-6.513335402999999,-5.610071838,-5.935332291,-7.118476157999999,-6.657355317,-4.71675294,-9.710546493530273,-9.808499336242676,-10.555351257324219,-8.833062171936035,-6.551031112670898 -2484,2484,G154T,-0.062763307,-0.038722972,-0.034677977,-0.441178694,-1.714924849,0.020651929,-0.041550035,-0.08397657900000001,-0.014438592,-0.019416766000000002,-0.058029177,-0.075559823,0.006203869,-0.180812372,-0.701545016,-1.8150401440000001,-1.6148095530000002,1.2556072059999999,1.3464179809999999,-9.046001777999999,-9.161574768,-8.854704681,-8.343149666,-8.588078156,-10.28250162,-8.363718524,-6.3006191,-10.157061576843262,-10.095322608947754,-11.429159164428711,-9.640222549438477,-8.865389823913574 -2485,2485,G154W,-0.010926739,0.085994918,0.004156222,-1.457664516,-2.49126502,0.0017444189999999999,-0.025393846,0.003540368,0.019962204,0.024786896,0.147202939,-0.060702926,0.06901536900000001,-1.21764196,-1.697687071,-2.151047724,-2.831482315,2.258185993,1.469591825,-10.85012607,-11.05415214,-10.27889148,-9.966582939,-10.69271499,-12.25828883,-9.659008957000001,-8.055785955,-13.227553367614746,-13.88222885131836,-15.328422546386719,-14.656466484069824,-11.544727325439453 -2486,2486,G154V,-0.171445638,-0.004294180999999999,-0.10647947099999999,-1.056478483,-1.669103351,0.015864218,-0.059711802,-0.283179474,-0.056097549000000003,-0.028923085,0.020334724,-0.11416792699999999,-0.09879101400000001,-1.338920343,-0.774036622,-2.290054874,-1.048151827,1.034825432,0.7547778470000001,-9.381235043,-9.859010956,-8.490148102000001,-8.257165894,-9.212892258,-11.08695801,-7.680342582000001,-4.759363595,-10.683577537536621,-11.513265609741211,-11.168121337890625,-11.539895057678223,-10.873431205749512 -2487,2487,G154Y,-0.031534836000000004,-0.019082992,-0.033905889,-0.6687876460000001,-2.3250405130000003,0.045010975,-0.03696074,-0.026108932,0.051832508,-0.13088909199999998,0.092723109,-0.10985722699999999,0.04204545,-0.35941440700000005,-0.978160884,-1.932204484,-2.7178765410000003,1.5468607669999999,1.373043656,-11.29682764,-11.10377769,-11.30934724,-10.19146714,-11.07056756,-12.80897854,-9.512232739,-7.853201445,-11.533002853393555,-12.79799747467041,-13.707596778869629,-12.731283187866211,-8.012214660644531 -2488,2488,D155A,0.003981678,-0.20967196800000001,-1.448112198,-2.198496364,-2.933485535,-0.0013367189999999999,0.036747615,-0.02878426,-0.043573245999999996,-0.133591914,-0.285752022,-1.475427345,-1.42079705,-2.092330415,-2.304662312,-3.142323272,-2.724647797,1.0188200920000001,0.07359441,-9.207470869,-10.23106146,-9.923379257,-8.397717247000001,-10.11960451,-7.365591873,-6.909303913,-2.1238134019999997,-10.5670747756958,-12.064985275268555,-9.33869457244873,-12.437398910522461,-10.813629150390625 -2489,2489,D155C,0.00015561,0.011852722,-1.071935327,-2.0017231509999998,-3.234446418,-0.000157991,0.012187513,-0.011876293999999999,-0.053970504,-0.02253401,0.046239454000000006,-0.953059836,-1.1908108179999999,-1.8004118269999998,-2.203034475,-2.920985758,-3.547907077,2.2737015069999997,1.020350433,-12.89184395,-14.16661003,-14.05482278,-12.16167262,-13.00244463,-11.07366968,-8.609268173,-2.630212658,-12.639492988586426,-13.501654624938965,-10.788812637329102,-14.62454891204834,-10.365777969360352 -2490,2490,D155E,0.036956696000000004,0.013681047,0.05328934900000001,-1.192240985,-1.954996729,-0.055472457999999995,0.090595774,-0.016682382,-0.043791933,-0.08474568199999999,0.11210777599999999,-0.0033517029999999997,0.10993039999999998,-0.676418237,-1.7080637330000001,-1.633135365,-2.276858093,2.234129801,1.747693142,-8.345086324,-9.666049606,-7.976600433,-7.096618294,-9.189830062999999,-7.796333221,-8.45181249,-5.876338106,-8.725896835327148,-10.274209022521973,-7.505153179168701,-9.489668846130371,-9.231226921081543 -2491,2491,D155G,-0.006902624,-0.500754898,-1.7094024909999999,-2.146929863,-2.9421224969999997,-0.000832541,0.028717602000000002,-0.04252285,-0.011127159,-0.392071916,-0.60943788,-1.6523558459999999,-1.766449135,-1.967685713,-2.326174012,-2.690319635,-3.1939253589999996,2.814822781,1.091849908,-10.86448262,-11.08599307,-11.25151942,-10.26652254,-11.75585658,-9.962521469,-8.082743788,-3.684269925,-11.664772033691406,-11.690650939941406,-10.229717254638672,-12.267393112182617,-10.974209785461426 -2492,2492,D155F,-0.091927257,-0.7010173959999999,-1.902495431,-2.137297715,-2.888915262,-0.025752186,-0.05073500400000001,-0.133119509,0.135611382,-0.5381226170000001,-0.863912175,-2.269153578,-1.5358372830000002,-2.116505569,-2.158089861,-2.538109496,-3.239721028,0.225128637,-0.5169833460000001,-13.09466582,-16.37061021,-12.13025437,-12.39965823,-12.92583975,-11.64696652,-8.306901282,-2.1752342369999997,-13.74372673034668,-13.690068244934082,-9.405418395996094,-15.67286205291748,-15.228328704833984 -2493,2493,D155I,-0.020107639,-0.25738182800000003,-1.56686465,-2.021333282,-2.7729508289999996,-0.156890409,-0.018263916,-0.021951361000000003,-0.153384495,-0.18941422,-0.325349436,-1.480006943,-1.653722357,-2.026328939,-2.016337625,-2.447932866,-3.097968792,3.20779388,1.5496245290000001,-11.56600494,-16.16951958,-11.99451606,-9.124165893999999,-11.3963289,-9.145494263,-6.134750105,-1.4906727780000002,-12.004137992858887,-14.416609764099121,-9.135040283203125,-14.880152702331543,-14.409294128417969 -2494,2494,D155H,0.037100771,-0.5904705960000001,-1.916107755,-2.301425038,-2.7520125889999996,0.054235995,0.073644235,0.000557306,-0.020945121,-0.462183778,-0.718757414,-1.7687157009999999,-2.063499808,-2.014007702,-2.5888423730000003,-2.7366416239999998,-2.767383553,2.897113103,1.084448845,-12.48529931,-13.93601223,-13.27072105,-11.1254513,-12.58130599,-11.51300599,-9.361902147999999,-5.509977217,-12.55717945098877,-9.96574592590332,-11.082432746887207,-14.189933776855469,-12.182415008544922 -2495,2495,D155K,0.053176642999999996,-0.98425512,-2.154494734,-2.7009216639999996,-3.063463586,-0.007847179000000001,0.08541662,0.020936665,-0.00738334,-1.085416537,-0.883093703,-2.47695925,-1.8320302169999998,-2.3243112409999998,-3.077532086,-2.7459151680000002,-3.381012003,0.44299559299999997,-0.6741532109999999,-13.1565329,-14.24897992,-14.37757285,-12.01937154,-13.81995053,-11.31678967,-10.09707451,-6.396893405,-16.047748565673828,-15.400729179382324,-13.158758163452148,-16.150131225585938,-16.516197204589844 -2496,2496,D155M,0.009467955,-0.36713878899999997,-1.692735469,-2.301631767,-2.863143693,-0.063756395,0.061422785,-0.04248687599999999,-0.0031605179999999997,-0.246392644,-0.48788493299999997,-1.4830333980000001,-1.9024375390000001,-1.93244538,-2.670818153,-2.7519893160000004,-2.97429807,2.829419601,1.200934606,-12.98772141,-17.06437338,-11.52828859,-12.67088252,-12.3828476,-11.29221494,-7.393728232999999,-2.332778638,-12.921351432800293,-14.227694511413574,-9.51264476776123,-14.785992622375488,-15.510416984558105 -2497,2497,D155L,-0.019981615,-0.806105347,-2.069682387,-2.164859561,-3.537996133,-0.029242232000000003,0.0031966259999999997,-0.043159855999999996,0.044183756,-0.65870638,-0.953504314,-2.176693185,-1.9626715890000002,-2.082037123,-2.247681999,-3.047709095,-4.028283171,0.7013862040000001,-0.479061443,-12.63340408,-17.16984715,-11.27880685,-11.74439623,-11.24773505,-11.7262351,-6.147999936000001,-0.566879436,-11.027301788330078,-13.872160911560059,-9.21094799041748,-13.956819534301758,-14.344979286193848 -2498,2498,D155N,-0.093440566,0.010202378,-0.0051764720000000005,-0.020706603,-2.020904202,0.026733311000000003,-0.051644987,-0.135236145,0.056993015999999994,0.005052681,0.015352073999999999,0.069958075,-0.080311018,0.07647804700000001,-0.117891253,-1.889193924,-2.15261448,0.6738330790000001,1.301847403,-7.752150746,-8.90872184,-7.910207832,-6.096100044,-8.265003006,-7.580721007999999,-6.752407783,-4.172019344,-10.056645393371582,-7.867307186126709,-9.589016914367676,-11.24603271484375,-9.084123611450195 -2499,2499,D155Q,0.012764072,-0.065839765,-1.371767942,-2.345130853,-3.309732767,0.04653792,0.049808827,-0.024280682999999997,-0.02622757,-0.057054970999999996,-0.07462455900000001,-1.0946018259999999,-1.648934057,-2.5440138080000003,-2.146247898,-2.965617735,-3.653847798,1.178927973,0.194664295,-12.81461205,-14.30453428,-13.43761433,-11.34158573,-14.14095853,-10.84836738,-9.204608973,-5.713355966,-13.481840133666992,-13.268264770507812,-11.328633308410645,-15.149399757385254,-14.364899635314941 -2500,2500,D155P,-0.010603617,-0.416758174,-1.780438571,-2.225378252,-2.8765383780000002,0.007792343,0.035763314,-0.056970547999999996,-0.027439132,-0.276614623,-0.5569017239999999,-1.5819493930000001,-1.978927748,-2.140505845,-2.310250658,-2.452965303,-3.300111452,2.63376026,0.9567953140000001,-12.96530857,-14.17996324,-12.290585400000001,-12.38065716,-13.01403873,-12.96129832,-8.54062337,-3.799485948,-15.32902717590332,-16.851287841796875,-12.67536735534668,-16.222299575805664,-16.4322509765625 -2501,2501,D155S,0.015492007,0.018535481,-1.142645951,-2.0369484819999997,-3.095545636,-0.006296648,0.049851541,-0.018867527,-0.032030609,-0.017832223,0.054903185,-0.8363414290000001,-1.448950473,-1.976503086,-2.097393878,-2.824075745,-3.367015527,2.034027718,0.850867907,-12.0553607,-13.55211435,-12.30636098,-10.99822547,-12.98038394,-10.43971877,-8.999876687999999,-5.648331817000001,-11.883665084838867,-12.545312881469727,-10.060163497924805,-13.009227752685547,-11.55783462524414 -2502,2502,D155R,0.008025082,-1.067685035,-2.004968133,-2.203675495,-3.133164207,0.002900218,0.045609745,-0.029559582,-0.016186597,-0.988828342,-1.1465417279999999,-2.0629506440000003,-1.9469856209999998,-2.0921462230000003,-2.315204766,-2.656417654,-3.609910759,0.31110525,-0.66159675,-13.79767848,-13.93984058,-15.46907941,-13.39449153,-14.32121756,-11.86376332,-9.081220149,-5.1584362960000005,-17.192895889282227,-15.969508171081543,-13.788755416870117,-16.461191177368164,-17.031591415405273 -2503,2503,D155T,0.02949894,-0.26524323,-1.56228049,-2.21896262,-3.098885595,0.001330697,0.071682359,-0.012684478999999999,0.008483184,-0.17311319100000003,-0.35737326799999997,-1.458564485,-1.665996495,-2.038310236,-2.399615003,-2.380732917,-3.817038272,3.193611821,1.55458012,-11.11340296,-13.17378031,-11.97400218,-9.644707405,-11.39491141,-9.37961351,-8.076540044,-4.355533942,-12.575119018554688,-13.975637435913086,-10.801076889038086,-13.930286407470703,-12.641164779663086 -2504,2504,D155W,0.014548159,-0.9637630309999999,-2.381639916,-2.344901135,-3.378654397,-0.020864026,0.045844660999999995,-0.016748343,-0.023315359,-0.851832376,-1.075693686,-2.771052718,-1.9922271130000002,-2.317374713,-2.372427556,-3.040008636,-3.717300158,0.383932525,-0.605268424,-15.39729887,-16.81671275,-15.45672027,-14.24447545,-16.2107851,-14.2578008,-9.296415058,-5.717255021000001,-15.837246894836426,-16.130586624145508,-12.045425415039062,-17.406444549560547,-18.955883026123047 -2505,2505,D155V,0.0306635,-0.36712141600000003,-1.5717429809999999,-2.41396719,-2.95260037,-0.030931757,0.056306691,0.005020308,-0.056937882,-0.313579575,-0.42066325600000004,-1.606677664,-1.5368082969999999,-2.123036436,-2.704897943,-2.8968228810000003,-3.008377859,2.636924189,0.931063943,-11.81194681,-15.08659561,-12.31832057,-9.509256859,-12.72650036,-9.419060669,-7.0874141,-2.353097959,-11.805368423461914,-13.25169849395752,-9.341647148132324,-13.943535804748535,-12.911043167114258 -2506,2506,D155Y,0.003428328,-0.90280407,-2.231455816,-2.355333726,-2.717875648,-0.029024407000000002,0.057534246,-0.05067759,0.00488892,-0.80382465,-1.00178349,-1.667093586,-2.795818045,-2.116505569,-2.594161882,-2.538109496,-2.8976417989999996,3.2949032760000003,1.3825458130000001,-13.94283793,-17.79250107,-15.6735612,-11.74413324,-13.55660533,-10.94738882,-7.382147565,-2.9841414410000002,-13.399687767028809,-12.14674186706543,-10.01864242553711,-14.06952953338623,-14.506402969360352 -2507,2507,H156A,0.000790751,-0.014790748000000001,-0.013775121999999999,-0.037463351,-0.069156908,-0.004613879,-0.057818935,0.059400437,-0.020166752,0.017633285,-0.04721478,-0.003919562,-0.023630681,-0.026940812999999997,-0.047985888,-0.045649842,-0.09266397300000001,1.2166231140000001,2.35890501,0.554502347,-0.07855938700000001,0.46700221299999994,1.583049004,0.23050519600000002,0.570514709,-2.86130536,0.72643388,-2.846853256225586,-3.52152419090271,-2.4633030891418457,-3.7461445331573486,-2.417116165161133 -2508,2508,H156C,0.020529604,-0.026537667,0.00045868,-0.014785688,-0.10513700699999999,-0.004878065,-0.021974345,0.06303355299999999,-0.065953279,-0.030274909,-0.022800424,0.013275179,-0.01235782,-0.013353091000000001,-0.016218284,-0.12216000099999999,-0.088114013,1.398410085,2.315654605,-3.445492822,-3.462221413,-3.1710599139999998,-3.1056262660000002,-3.3571427839999997,-4.131413734,-6.182460047999999,-3.128659228,-7.213716983795166,-7.843626976013184,-8.182439804077148,-8.67237377166748,-8.871280670166016 -2509,2509,H156E,-0.037762956,-0.004816341,-0.026718718,-0.047354441,-0.060026062000000005,-0.054687259,-0.054157405,-0.021368507000000002,0.02297905,0.007668952,-0.017301633,-0.016207016,-0.03723042,-0.063252606,-0.031456276,-0.057230477,-0.06282164700000001,1.215770099,2.256930721,1.240963054,0.779028107,1.419941666,1.663993355,0.9075558090000001,1.434296333,-2.406000821,1.173918051,-1.6362395286560059,-2.8604726791381836,-0.6604514122009277,-2.8052961826324463,-1.2311125993728638 -2510,2510,H156D,-0.025354698999999998,0.016333765,-0.011982939,0.0052694890000000005,-0.030105332000000002,0.009855463,-0.029827015,-0.020882383,0.036641783,0.015788006,0.016879523,-0.006846,-0.017119878,-0.027356377,0.037895355,-0.012306783,-0.04790388,1.202027832,2.511116909,0.844047131,0.855781097,0.901944038,1.536604256,0.8065735629999999,0.11933270300000001,-2.8425578999999996,1.2268215040000001,-1.7910020351409912,-3.1226885318756104,-0.5781280994415283,-3.450443744659424,-1.8674670457839966 -2511,2511,H156G,0.009082244,-0.011025031000000001,-0.023313008,-0.023926916,-0.087994099,-0.006198773,-0.037914523,0.05607901,-0.018761121999999998,0.019916907,-0.041966968,0.008720235,-0.055346251,-0.01456751,-0.033286321,-0.055661071,-0.12032712699999999,1.433653085,2.5771412259999997,0.491278864,-0.565281364,0.3980131,1.437023872,0.50423217,0.68240654,-2.830481761,0.485418576,-3.4477286338806152,-4.6148834228515625,-3.0635976791381836,-4.433407783508301,-3.2825684547424316 -2512,2512,H156F,-0.006938268,0.018674223,0.022466152000000003,0.002627122,0.009488401,-0.030445031,-0.011809397,-0.002067139,0.013887321999999999,0.042887611,-0.005539165,0.053878397,-0.008946094,-0.002073009,0.007327251999999999,0.034957439,-0.015980638000000002,1.132951632,2.714552607,-4.550800871,-3.773891388,-3.639100235,-5.003751221,-4.462842361,-5.874419151000001,-6.578897344,-3.7195397480000003,-6.6826887130737305,-6.462499618530273,-6.088244438171387,-7.784850120544434,-6.140627861022949 -2513,2513,H156I,0.009215622,-0.040755232,-0.039775838,-0.052229063,-0.15501738199999998,-0.047527992000000005,-0.027372265,0.045803509000000006,-0.002574528,-0.002109198,-0.079401265,-0.01205723,-0.067494446,-0.04591243,-0.058545695,-0.133365811,-0.17666895300000002,1.402876335,2.227808267,-2.441491991,-2.5159610519999998,-2.093189796,-2.30176265,-2.158230331,-3.1383161239999997,-5.042377543,-1.857423461,-5.858489990234375,-5.1810302734375,-5.032046318054199,-6.818187713623047,-5.456923484802246 -2514,2514,H156K,-0.067011842,-0.026198547000000003,-0.003989321,-0.003006977,-0.023280442000000002,-0.010627066999999999,-0.061403300999999993,-0.072620382,0.061927561,0.011090227,-0.06348732,0.050448234,-0.058426875999999996,-0.005524669,-0.000489285,-0.019587873000000002,-0.02697301,1.289824957,2.5302698830000003,0.656068959,0.316260223,1.042140244,0.578792274,0.8026498259999999,0.5405022279999999,-2.7150628930000003,1.5061151080000001,-2.33767032623291,-2.5596635341644287,-2.117485761642456,-1.8604176044464111,-1.8636394739151 -2515,2515,H156M,0.0273606,0.028954825,0.030014758,0.028995526,0.013323853,-0.012058569,-0.013935778000000001,0.06865697700000001,-0.016352263,0.035718806,0.022190843,0.044585861,0.015443655,0.009531082,0.04845997,-0.020081785,0.046729491,1.145623364,2.5581189269999998,-1.508091638,-2.022221268,-1.3132953490000001,-0.76925148,-1.350404381,-2.085285713,-4.425726222,-1.605335791,-5.64171028137207,-5.092507362365723,-5.556451320648193,-5.9093017578125,-4.196072101593018 -2516,2516,H156L,-0.008777801,-0.012408425,-0.000862018,-0.018975888,-0.057332812999999996,-0.005969574,-0.04873799,0.031182388999999998,-0.017795249,0.0057529980000000005,-0.030569847,0.031009441000000002,-0.032733476,-0.022130003,-0.015821771999999998,-0.025392261,-0.08927336400000001,1.274597881,2.5472242119999997,-1.296251505,-1.6404417880000002,-0.823567719,-0.9308963929999999,-1.087508385,-1.9988432390000002,-3.908018778,-1.282033687,-5.627872467041016,-5.1122941970825195,-5.115006446838379,-6.152702331542969,-5.047181129455566 -2517,2517,H156N,-0.075020577,-0.023835533,0.035573827,0.000245875,0.000899269,-0.01195473,-0.08249731099999999,-0.06754384299999999,0.006163373000000001,0.005927321,-0.053598387000000004,0.045875765,0.025271889,-0.022665807000000003,0.023157557000000002,0.017778823,-0.015980285,1.229041836,2.626579444,0.842663411,0.338358139,0.791988831,0.9872727659999999,1.7067079319999998,0.388989388,-1.550499162,0.691510105,-1.6568102836608887,-2.488022804260254,-2.0951967239379883,-2.150838851928711,-1.8946317434310913 -2518,2518,H156Q,-0.035321248,0.006921984,-0.014062934,-0.028171835,-0.03615346,0.005126955999999999,-0.025955205,-0.044687291,-0.031855791,0.017866987,-0.00402302,0.00817785,-0.036303718,-0.022739432,-0.033604237,-0.014396073999999998,-0.057910845,1.2999896229999999,2.6560617509999997,1.1379052920000001,0.0897827,1.406170601,1.286998787,1.36230999,1.5442643809999999,-1.328632852,0.61780149,-2.594326972961426,-2.555034637451172,-1.8696269989013672,-3.084519386291504,-1.86117422580719 -2519,2519,H156P,0.013109826000000002,-0.017643746000000002,-0.008143436,-0.025070528999999998,-0.09989242400000001,-0.011720571,-0.040235192,0.066454844,-0.022467425,0.011110215,-0.046397706,0.0054489809999999994,-0.021735852000000003,-0.028359577,-0.021781481000000002,-0.072473417,-0.127311431,1.3603882040000002,2.4288243,0.796035635,-0.20100656100000003,1.5085631330000002,1.746077835,0.39738263700000004,0.529161133,-2.271937013,0.8126102690000001,-2.626887798309326,-3.6640374660491943,-1.465073823928833,-3.5130679607391357,-1.1019388437271118 -2520,2520,H156S,0.013185253999999999,-0.023367033,-0.010695743,-0.010834193999999998,-0.044113082000000005,-0.01676159,-0.039234964,0.065605471,0.011227791,0.003577463,-0.050311529,0.011619984,-0.03301147,-0.020846313,-0.000822075,-0.015306662,-0.072919502,1.205719968,2.5626718719999997,0.985202245,0.658240845,1.2812284999999999,1.191527809,0.944833473,0.850180595,-1.7927762999999999,0.93399516,-1.853212594985962,-2.0886247158050537,-2.1228342056274414,-2.728698253631592,-1.722331166267395 -2521,2521,H156R,0.00577665,-0.011233411,-0.01747603,-0.038466957999999996,-0.050996883,-0.0024974520000000003,-0.026565659,0.038118959,-0.013646666000000002,0.000573681,-0.023040502999999997,-0.004611149,-0.030340911,-0.042605682,-0.034328233,-0.036668096000000004,-0.06532567,1.310160679,2.512602045,0.6266842579999999,-0.16905329100000002,0.653560593,1.333411972,0.03436438,1.281137634,-2.124178407,1.08640425,-3.343106746673584,-2.823450803756714,-3.430189609527588,-3.4967358112335205,-2.982243061065674 -2522,2522,H156T,0.010346685,-0.009582917,-0.010314859000000001,-0.009820460999999999,-0.026805845,-0.02336808,-0.043461836,0.064155205,0.016238285,0.047302013,-0.066467847,0.034949527,-0.055579245,0.023591427,-0.043232349,0.026456351,-0.08006804,1.251121256,2.93995983,1.27834319,1.014416122,1.5138544459999999,1.651493874,1.1599047009999999,1.052046806,-2.70010411,1.6710117480000002,-1.708695888519287,-1.758500337600708,-1.684523105621338,-2.4762587547302246,-1.5669089555740356 -2523,2523,H156W,-0.025378777,0.009689666999999999,-0.005721979,0.014182097,-0.042865849000000004,-0.014523413,-0.070279275,0.019521722,-0.011595542,0.055117669,-0.035738336,0.022825967000000003,-0.034269925,0.01136923,0.016994963999999998,-0.032056797000000005,-0.053674900000000005,1.1920843540000001,2.4699333230000002,-3.8229549730000003,-3.68084642,-3.427587982,-3.5603467330000003,-4.161780327,-4.284213402,-6.545712343,-3.473903061,-7.664610385894775,-9.361824035644531,-7.912944793701172,-9.134178161621094,-5.398385524749756 -2524,2524,H156V,-0.036787787999999995,-0.028977481,-0.030686662000000003,-0.037564021,-0.079730457,-0.021039885,-0.100679689,0.027104114,-0.020340733,-0.011958553,-0.045996409,0.028093053,-0.08946637699999999,-0.017841799,-0.057286242,-0.05447889,-0.10498202400000001,1.3665213569999999,2.44779904,-1.2476062270000001,-0.922966278,-1.104612732,-1.07015863,-1.4756937940000001,-1.664599701,-4.437423739,-0.600127589,-4.914543628692627,-4.929597854614258,-4.116462707519531,-5.739643096923828,-4.095821857452393 -2525,2525,H156Y,-0.064005058,0.020429122,0.012173881999999999,-0.027288503,-0.002911655,0.041098586,-0.059093424000000006,-0.068916692,-0.035449785,0.070976361,-0.030118117000000003,0.042229301,-0.017881537,-0.008059077,-0.046517929000000006,0.028469435,-0.034292744,1.125323858,2.573922852,-3.0584385419999998,-2.54501503,-2.665190285,-3.2719638439999996,-3.025360451,-3.784663101,-5.347297279,-2.127439768,-6.257061004638672,-5.80655574798584,-5.427268028259277,-6.370512008666992,-5.275304317474365 -2526,2526,V157A,0.007986192,0.009309956999999999,-0.021504657000000003,-0.037041243,-0.049961013,-0.045121338,-0.02201055,0.037982932999999997,0.027922016,-0.021914187,0.0405341,-0.063905856,0.020896542,-0.049213235,-0.024869251000000002,-0.07953139099999999,-0.020390633999999998,1.329353049,2.299317259,-3.169581964,-3.6593495560000004,-3.4254684369999997,-2.7850598069999997,-2.948949608,-3.0290824130000003,-4.279568631,-1.4398976019999998,-7.772057056427002,-6.860175609588623,-6.652058124542236,-6.077880382537842,-6.369265079498291 -2527,2527,V157C,0.084954012,0.012562658,0.025972172999999998,0.012285342,-0.134334239,-0.004265398,0.078120435,0.091787589,-0.0028093709999999997,-0.06265530700000001,0.08778062199999999,-0.06438972400000001,0.11633407,-0.038264444,0.062835127,-0.162790796,-0.105877681,1.391379159,2.1955583880000002,-7.321403911,-7.892734428,-7.202978905,-6.863465248,-7.244085747000001,-7.403755226,-7.986200681000001,-5.469944189,-9.891212463378906,-8.87641429901123,-9.849407196044922,-9.481254577636719,-10.070110321044922 -2528,2528,V157E,-0.10696642199999999,0.017066138,-0.041678455,-0.025078306,-0.058903587,-0.004520905,-0.153480035,-0.060452809,-0.056893665999999996,0.067774528,-0.033642253,-0.023431617999999998,-0.059925292000000005,0.015065903,-0.065222515,-0.035689096000000003,-0.082118078,1.117367883,2.476741575,-3.25021282,-3.876705284,-2.877288437,-3.41701593,-3.3428270419999997,-2.737227409,-4.136290335,-1.422860953,-8.312336921691895,-6.447779655456543,-6.880902290344238,-5.36350154876709,-6.7814178466796875 -2529,2529,V157D,-0.0020443370000000002,0.005075446,-0.00477866,-0.079742038,-0.082892483,-0.09744030099999999,-0.0628855,0.058796827,0.00106587,-0.0039149729999999995,0.014065863999999999,0.00782752,-0.01738484,-0.070744501,-0.088739575,-0.150696235,-0.01508873,1.463569959,2.22689915,-4.612984422,-5.450246155,-4.859641068,-4.161918457,-3.95824292,-4.6348735119999995,-5.801194455,-0.513878806,-9.943832397460938,-7.3359375,-8.003866195678711,-6.530273914337158,-7.973244667053223 -2530,2530,V157G,0.10794594800000001,0.191189492,0.01376128,0.003002917,-0.292355779,-0.011331775,0.074179539,0.14171235599999998,0.027074472999999998,0.180638887,0.20174009699999998,0.038368337999999995,-0.010845778,0.057385578,-0.051379744000000005,-0.212819433,-0.371892125,1.095799386,1.869075274,-6.0220802220000005,-7.648190269,-4.6925456389999995,-5.270106941,-5.8960850979999995,-6.60347316,-5.548830965,-0.548143617,-10.755119323730469,-9.535257339477539,-7.917603492736816,-7.679654121398926,-8.89819049835205 -2531,2531,V157F,-0.007756688,0.003720795,-0.022351098,-0.055792264,-0.033174397,-0.07926577900000001,-0.019010585,0.0034972090000000003,0.022708491,-0.025023884,0.032465472999999995,-0.07319880599999999,0.028496611,-0.016428786,-0.095155741,-0.113066796,0.046718002,1.4009049219999998,2.277511735,-4.6704772089999995,-4.969606888,-4.352804314,-4.898512177,-4.524869492,-4.606593178,-5.820973962999999,-4.535583336,-9.028268814086914,-7.708927154541016,-8.948649406433105,-7.715367794036865,-8.592875480651855 -2532,2532,V157I,0.008875801,0.035812307,0.014339178999999999,0.008850037,-0.016144166,-0.087609895,-0.016888417,0.034640018,0.009676286999999999,0.047326115,0.024298497999999998,0.041091196,-0.012412838,0.014698422,0.0030016509999999997,0.018967839,-0.051256170999999996,1.1122792190000002,2.6324447930000003,-1.6409339859999998,-1.62044603,-1.5254786759999999,-1.7513616330000001,-1.825927551,-1.481456039,-2.819401069,-2.073549086,-5.208096027374268,-4.514705657958984,-5.1937713623046875,-5.268051624298096,-4.905713081359863 -2533,2533,V157H,-0.044571050999999993,0.060833498,0.033880164,0.00034067900000000004,-0.028670375,-0.075986231,-0.09326186,0.004119758,-0.069118608,0.048976245,0.07269075,0.055996382000000004,0.011763946,0.047731714,-0.047050355999999995,-0.045777879,-0.01156287,1.19428499,2.477242401,-4.302297868,-4.704184357,-4.766113251,-4.0632901310000005,-3.7877821039999997,-4.190119499,-5.135493435,-1.5600190280000001,-9.790351867675781,-7.489936351776123,-8.41903305053711,-7.103541851043701,-8.016780853271484 -2534,2534,V157K,0.022282207000000002,0.014994963,-0.008282013000000001,0.0008595639999999999,-0.06893156,0.016136523,-0.031403631,0.075968044,-0.031896207999999995,-0.017291521,0.047281446,-0.051811308,0.035247283,-0.0056121980000000005,0.007331325,-0.09863342300000001,-0.039229696,1.343734125,2.293345447,-3.253023756,-3.905307495,-3.620977875,-3.6851141739999997,-3.029333694,-2.0243855440000003,-4.328695129,-1.929641125,-9.196980476379395,-8.982279777526855,-8.274114608764648,-7.053728103637695,-7.420822620391846 -2535,2535,V157M,0.02340169,-0.019685983,-0.019215341,0.011822794,-0.110101585,-0.078687083,0.014002998000000001,0.032800381,0.05095052,-0.05962771,0.020255745,-0.039449345,0.001018663,-0.038077633,0.061723220999999995,-0.118598559,-0.101604611,1.396889719,2.271492265,-3.099042305,-2.393574715,-2.7700798260000004,-3.1501124039999997,-3.352951286,-3.828493294,-3.9438601560000004,-3.458638005,-8.418773651123047,-7.053199768066406,-8.194043159484863,-6.3777570724487305,-7.604877948760986 -2536,2536,V157L,-0.016502679,0.00856212,-0.024722348999999998,-0.027218815,-0.159833685,-0.051930040999999996,-0.030786418,-0.00221894,-0.020383651000000003,-0.023481096,0.040605336,-0.056048905999999996,0.006604208,-0.031286181,-0.023151448999999998,-0.161697204,-0.157970165,1.612664549,2.3511978609999997,-2.975976044,-2.94330793,-3.074684273,-2.514048073,-2.625054993,-3.72278495,-5.01423233,-2.978221397,-7.153245449066162,-5.813449859619141,-7.107738018035889,-5.284241199493408,-7.334786891937256 -2537,2537,V157N,0.000198755,0.03000856,-0.031966483,-0.004686483,-0.148758043,0.020972032,-0.0021186079999999997,0.002516117,-0.023868458,0.019487978,0.040529142000000004,-0.08558820199999999,0.021655236,-0.009035113,-0.00033785300000000005,-0.133638187,-0.163877899,1.288931804,2.2115706569999998,-4.727192067,-5.578263596,-4.589474457,-5.069303925,-4.866163574,-3.5327547839999998,-6.067978776,-0.8715916309999999,-9.46746826171875,-7.879034042358398,-8.207700729370117,-7.193731307983398,-7.432570934295654 -2538,2538,V157Q,-0.028725188,0.033604028,0.033820561,-0.061760167000000005,-0.034791114,-0.084827921,-0.101191564,0.04374118900000001,-0.032561979,0.012268268,0.054939787999999996,-0.010704248999999999,0.078345371,-0.032506184,-0.09101415,-0.061165620999999996,-0.008416606,1.4040708259999999,2.462408032,-2.9527749880000003,-3.366416473,-3.414064003,-2.88609211,-2.762900558,-2.334401794,-4.400198822,-1.245940109,-8.784072875976562,-7.481479644775391,-7.06627893447876,-4.823993682861328,-6.658679008483887 -2539,2539,V157P,-0.023004699,0.03979491,-0.8276222990000001,-1.9120909959999999,-2.508478619,-0.015592914,-0.014112959,-0.031896438,-0.024791543,0.015971676,0.063618144,-0.537258239,-1.117986359,-1.731426245,-2.092755747,-2.316537655,-2.700419583,1.74226861,0.84392402,-7.171530978,-8.132885482999999,-6.945380248999999,-6.580752251,-6.756553557999999,-7.442083351,-6.160434565,-4.1539961839999995,-9.65210247039795,-10.451592445373535,-9.76730728149414,-9.792118072509766,-9.635980606079102 -2540,2540,V157S,-0.004358762,0.033163936,-0.001189644,-0.009443115,-0.068319607,-0.06028089,-0.038997988,0.030280465,-0.01391897,0.005455021,0.06087285,-0.019964785,0.017585497,-0.005281905999999999,-0.013604324,-0.047715981,-0.088923233,1.2621329940000001,2.44424151,-3.60658513,-4.741048286,-3.5495954060000003,-3.3129704739999997,-3.2466201860000004,-3.1826912989999996,-4.140282437,-1.38262434,-8.432899475097656,-7.481538772583008,-6.533337593078613,-5.725435256958008,-6.805145263671875 -2541,2541,V157R,0.011059736,0.04024141,0.019991246,-0.012669237,-0.100719758,0.005986241999999999,-0.013690598,0.03581007,-0.006412719,0.018381351,0.062101468,-0.012765894,0.052748385999999994,-0.028494431,0.003155957,-0.120336125,-0.08110339,1.409320366,2.280302418,-4.568367793,-5.627642571,-4.679623375,-3.990448166,-3.7756510160000003,-4.768473838999999,-5.734794798999999,-1.423671343,-9.230134963989258,-9.248336791992188,-8.628983497619629,-7.263123035430908,-7.786106586456299 -2542,2542,V157T,-0.022025257000000003,0.019373934,0.004638975,-0.011490753000000001,-0.050944736,-0.009981433,-0.050543999000000006,0.006493486,-0.014280938,0.018145144,0.020602723,-0.007243716999999999,0.016521667,-0.012138635,-0.01084287,-0.069706728,-0.032182743,1.3596033180000002,2.454671115,-1.154105035,-1.4847883830000002,-1.0754944990000002,-1.170520035,-1.359177597,-0.6805446620000001,-1.968892619,-0.629145117,-5.719082832336426,-4.924190044403076,-4.610115051269531,-4.7274346351623535,-3.3739261627197266 -2543,2543,V157W,0.007498571999999999,0.071943872,0.046693488,-0.014799063999999999,-0.063348543,0.006335748,-0.008847174000000001,0.023844318,-0.02232801,0.052239618,0.091648125,0.016267613,0.077119362,0.013688938000000001,-0.043287066,-0.09457019900000001,-0.032126886,1.346578525,2.32614318,-5.8764666839999995,-6.500454124,-5.568955223,-5.456357124,-5.407332962000001,-6.449233986,-6.824008517,-4.798203921,-12.968207359313965,-11.234373092651367,-11.674015045166016,-10.525947570800781,-10.183759689331055 -2544,2544,V157Y,-0.026986842999999996,0.089823681,0.071057583,0.019410524,0.0042194,-0.054327478,-0.062310576,0.008336890999999999,0.008647984000000001,0.10194207400000001,0.077705288,0.080452194,0.061662971,0.07784526,-0.039024212999999995,0.017561899,-0.009123099,1.301330514,2.932170999,-4.273006175,-4.2795890960000005,-3.33531147,-5.004244934,-4.744499374,-4.001386002,-4.798036843999999,-3.5350816110000003,-10.713048934936523,-7.604896545410156,-8.765705108642578,-7.95799446105957,-8.528489112854004 -2545,2545,T158A,-0.028880463,-0.011968048,-0.0169454,-0.121961116,-1.75776431,-0.050037362,-0.030818876000000002,-0.026942049,-0.044752917999999996,-0.016594137,-0.007341958000000001,-0.015432313000000001,-0.018458486,-0.071642508,-0.172279723,-1.706419375,-1.809109245,0.91354021,1.322989124,-6.74590338,-6.753515366,-6.024180199,-6.620997185,-7.572899917999999,-6.757924232000001,-7.615992122000001,-5.09847707,-5.796302318572998,-10.445124626159668,-7.990542888641357,-10.329891204833984,-13.441488265991211 -2546,2546,T158C,0.014937236000000001,-0.059811937,-0.35263371600000004,-1.979025918,-2.074436607,-0.066666054,0.03415179,-0.004277319,-0.017442138,-0.097693744,-0.021930129,-0.18645555100000002,-0.51881188,-1.461092812,-2.496959023,-2.195292493,-1.95358072,2.521829597,1.552393897,-8.816079497,-9.111968544,-7.680197968,-9.358273827,-8.877467171000001,-9.052489975,-8.306899929,-5.248514957,-6.991052627563477,-11.66240119934082,-9.183460235595703,-11.505180358886719,-14.836466789245605 -2547,2547,T158E,-0.08650744699999999,-1.175465311,-1.994885235,-2.4617506959999997,-2.826795965,-0.038013063,-0.10460106699999999,-0.068413827,-0.029609500000000004,-0.973438626,-1.3774919959999998,-2.142191176,-1.847579294,-2.101827499,-2.8216738930000003,-2.676326337,-2.9772655930000003,0.339241367,-0.633590368,-10.49318647,-10.61954129,-8.337820236,-10.82387936,-12.14736702,-10.53732446,-9.656081126,-7.636737711,-10.43227481842041,-15.591838836669922,-11.331984519958496,-14.040196418762207,-18.457250595092773 -2548,2548,T158D,0.095400055,-0.5866281329999999,-2.054794181,-2.158160277,-2.857708937,-0.06140133,0.14687877300000002,0.043921336,-0.027128158,-0.494761846,-0.6784944190000001,-2.402412347,-1.707176014,-2.237109933,-2.079210621,-2.635517512,-3.079900362,0.401892611,-0.486329356,-10.78483629,-10.97438513,-9.745017288,-11.03253608,-11.59516908,-10.57707387,-9.710414099,-7.636737711,-10.129457473754883,-14.572355270385742,-10.35706901550293,-13.388738632202148,-17.549579620361328 -2549,2549,T158G,-0.028441239,-0.010144088,-0.038873325,-0.957233643,-2.322613955,-0.012227968,-0.011574282,-0.045308195,-0.034284426,-0.020700154,0.00041197900000000003,-0.052958625999999995,-0.024788023,-0.44292479,-1.471542495,-2.04714551,-2.598082399,1.7311426269999999,1.35983682,-5.615739685,-6.421732544,-5.241361717,-5.506715347,-6.070659134,-4.838229683,-6.376746154,-4.621285299,-7.725307941436768,-11.991888999938965,-8.292830467224121,-13.591519355773926,-15.97712230682373 -2550,2550,T158F,0.061257886,0.013099162,-0.031020341,0.023313035,-1.662542725,0.044757627,0.117896604,0.004619168,-0.014174414,-0.020031826000000003,0.046230149000000005,-0.13126633099999999,0.06922565,-0.045145162999999995,0.091771232,-1.686590791,-1.638494659,0.808514785,1.318118766,-6.339188605,-6.327151306,-5.758313309,-7.2369213939999995,-6.454403725,-5.91915329,-5.575406967999999,-1.814040475,-2.333589553833008,-9.784591674804688,-7.8085126876831055,-10.565531730651855,-14.054854393005371 -2551,2551,T158I,0.09018035199999999,0.042909660999999995,-0.289801071,-2.0700840830000002,-2.619117745,0.063354391,0.132504931,0.047855773,-0.076993383,-0.031875053,0.117694375,-0.24467862899999998,-0.334923513,-1.464727097,-2.675441069,-2.40720272,-2.83103277,1.42695384,0.820807066,-6.728567758,-7.633880249,-4.275447784,-7.002468155,-6.90516394,-7.825878662,-6.8529601179999995,-1.6219367130000002,-7.954522609710693,-11.013744354248047,-9.044228553771973,-11.286239624023438,-13.465243339538574 -2552,2552,T158H,-0.005887926,-0.129997274,-1.4000168819999999,-2.3767000780000003,-3.153699718,-0.034001792999999995,0.005409353,-0.017185204,-0.039494911,-0.143775044,-0.116219504,-1.418283014,-1.381750749,-2.508253105,-2.24514705,-2.9066606839999998,-3.4007387510000004,1.045653183,0.089653149,-11.97797269,-12.26819915,-10.0723007,-11.69131924,-12.85421696,-13.00382738,-10.50509567,-9.990787985,-8.242683410644531,-14.284686088562012,-10.176668167114258,-14.7567138671875,-17.687719345092773 -2553,2553,T158K,-0.019445796,-1.420475329,-2.577818355,-2.6811844519999997,-2.6571540959999997,-0.00726131,0.012847468999999999,-0.05173906,-0.103740919,-1.6585575190000001,-1.182393138,-2.2990362909999997,-2.856600418,-2.434763874,-2.92760503,-2.5321414559999997,-2.782166735,-0.083982765,-1.0795121140000001,-10.71000277,-10.39429324,-9.358348595,-10.42260023,-11.86147739,-11.51329439,-9.705296779,-7.636737711,-12.323857307434082,-14.460875511169434,-13.392036437988281,-14.69765567779541,-18.094406127929688 -2554,2554,T158M,-0.088305607,-0.050163998,-0.371490407,-2.118906559,-2.833436831,-0.045057174000000005,-0.06938122299999999,-0.107229991,-0.068086765,-0.045216517000000005,-0.055111479000000005,-0.22754187399999998,-0.515438939,-1.935366224,-2.302446894,-2.509865062,-3.1570085989999996,1.227098972,0.692747039,-7.404449721000001,-7.994227477999999,-5.952948532000001,-7.277151054,-8.556643692,-7.241277847,-5.79062572,-2.88888606,-7.359887599945068,-11.76924991607666,-9.683051109313965,-10.231646537780762,-14.187952041625977 -2555,2555,T158L,-0.074344656,-0.35571971,-1.565843171,-2.350798219,-2.71824293,-0.011836931,-0.069025053,-0.079664259,-0.032444284,-0.198216444,-0.513222975,-1.45411917,-1.6775671719999998,-2.221869967,-2.4797264709999998,-2.465375585,-2.971110274,1.569433326,0.210169994,-7.034857142999999,-8.723049377,-4.963083763,-7.669684265,-8.545335129,-5.273133178999999,-6.068846075,-3.1788365489999997,-6.590643882751465,-11.957474708557129,-9.688642501831055,-12.937460899353027,-14.813087463378906 -2556,2556,T158N,0.011774083999999999,-0.191109825,-1.2999960990000001,-2.332028445,-2.847588712,-0.017818102,0.063519486,-0.039971319,-0.02202226,-0.091459631,-0.290760018,-1.148474901,-1.4515172969999999,-2.011201211,-2.6528556780000003,-2.585700049,-3.109477374,2.402240575,0.9828210620000001,-8.914365842,-8.973008232,-7.3534499360000005,-9.233376418999999,-10.54631986,-8.465674759,-9.025374329,-6.703583065,-8.714189529418945,-11.590237617492676,-9.285816192626953,-11.155213356018066,-13.59020709991455 -2557,2557,T158Q,-0.018011008999999998,-0.41006510700000004,-1.807096801,-2.347026279,-2.561556551,-0.04480964,-0.023189957,-0.012832061,-0.037983725,-0.237807839,-0.582322374,-1.658693942,-1.955499659,-2.220390256,-2.4736623019999997,-2.493859098,-2.6292540030000002,1.146779821,0.041487212,-9.627094266,-9.871858261,-7.307986794,-9.874044067,-11.7535477,-9.328034508,-7.990517695,-4.709698207,-10.395100593566895,-15.44180679321289,-11.193639755249023,-14.49620246887207,-16.16124725341797 -2558,2558,T158P,-0.047265934,-0.861978129,-1.937056479,-2.371801492,-2.6938364260000003,-0.04161215,-0.03852653,-0.056005337,-0.001364811,-0.7088969079999999,-1.0150593490000002,-1.897852844,-1.976260114,-2.179708461,-2.563894522,-2.550087316,-2.837585535,2.920946179,0.9539960059999999,-10.28377697,-10.21614412,-9.169962257,-10.40614236,-11.48169687,-10.14493927,-9.580546624,-7.606890400000001,-10.49203872680664,-12.659492492675781,-11.639270782470703,-14.247004508972168,-16.575775146484375 -2559,2559,T158S,0.015033753,0.011266874,-0.020908291000000002,0.004136106,-0.018715579,-0.054606494000000005,0.0031374109999999997,0.026930093999999998,-0.034150704,-0.023250323,0.04578407,-0.001956087,-0.039860495,-0.017824458,0.02609667,-0.038154924,0.000723766,1.441341456,2.634085791,-1.995040804,-1.887696579,-2.629198944,-2.067860832,-2.901416771,-0.489030891,-2.7079398830000003,-1.804535775,-2.540407657623291,-3.786740303039551,-5.398008346557617,-6.035053253173828,-7.351306915283203 -2560,2560,T158R,0.000780494,-1.5853249759999999,-2.073623984,-2.313490717,-2.8290509839999998,-0.024743489,0.0008451610000000001,0.000715826,-0.118243952,-1.710866618,-1.459783333,-2.147225408,-2.00002256,-2.203771744,-2.42320969,-2.4772405859999997,-3.180861382,-0.23548121800000002,-1.118950065,-11.18140742,-11.19978569,-8.817960402999999,-11.50193285,-12.57058962,-11.81676853,-9.647283605,-7.636737711,-11.633244514465332,-13.69377613067627,-12.053706169128418,-12.584962844848633,-18.589906692504883 -2561,2561,T158W,-0.001048914,-0.852970888,-1.935432754,-2.456870449,-2.855389113,-0.10954254699999999,0.002327036,-0.004424863,0.013381811,-0.755467532,-0.9504742429999999,-1.8993964980000002,-1.971469009,-1.792086031,-3.1216548669999997,-2.7345616539999997,-2.976216572,3.502028469,1.558197055,-10.85864467,-11.29701408,-9.937060265,-11.85011852,-11.22084641,-9.988184059,-8.610340115,-6.026166153999999,-8.6389741897583,-15.588401794433594,-11.447296142578125,-15.26995849609375,-20.235525131225586 -2562,2562,T158V,-0.041539086,0.016103403999999998,-0.011243436,-1.232293488,-2.060039083,-0.018751731,-0.016265212,-0.06681296,-0.020814413,0.014433643000000001,0.017773163999999998,-0.009772115999999999,-0.012714756,-0.7067656179999999,-1.7578213569999999,-2.0624212159999997,-2.057656949,1.812751878,1.3843838819999998,-7.682841161,-8.622737572,-5.495376274,-7.336580681,-8.307325401,-8.652185875,-6.931224667,-2.9142473310000003,-7.257011890411377,-13.402334213256836,-8.931634902954102,-11.434150695800781,-14.652275085449219 -2563,2563,T158Y,-0.057431450999999994,-0.602050125,-1.741436873,-2.505912618,-2.632397259,-0.018531815,-0.074692985,-0.040169916,0.006374023,-0.48246626,-0.7216339890000001,-1.533119497,-1.949754248,-2.51394512,-2.497880115,-2.611322702,-2.653471815,1.7433931480000002,0.237707975,-9.692380902,-9.5484132,-9.006973946,-10.43711009,-8.428070961,-11.04133631,-7.420787025,-4.970833928,-5.156891822814941,-13.912776947021484,-9.046667098999023,-14.022852897644043,-17.803871154785156 -2564,2564,R159A,-0.041589751,0.018099699,-0.016078471,-0.009174969,-1.81998913,-0.054365795999999994,-0.038926342999999995,-0.044253158,-0.140360605,0.037816101,-0.0016167039999999998,-0.003455391,-0.028701551000000002,0.020323466999999998,-0.038673405,-1.573000696,-2.066977563,0.6060222120000001,1.3126331629999999,-10.06333203,-9.202413597,-9.392203819,-10.83267946,-11.05130489,-9.838058372999999,-8.611336742,-2.3731766469999998,-9.748406410217285,-13.070815086364746,-8.319465637207031,-10.826973915100098,-11.424810409545898 -2565,2565,R159C,-0.051000738,-0.045488390999999996,-0.044300819000000005,-0.043935397,-1.598124144,-0.072430628,-0.026491672,-0.075509803,-0.075250295,-0.006108904,-0.084867877,0.014719382,-0.103321019,0.028477809,-0.11634860300000001,-1.295489328,-1.90075896,0.8802841090000001,1.3494737769999998,-12.31606937,-11.27984914,-12.00466442,-14.16630684,-12.73819745,-11.39132899,-9.266848145,-5.30288059,-9.601251602172852,-11.740767478942871,-9.4598970413208,-11.731221199035645,-11.120479583740234 -2566,2566,R159E,0.031932327,-0.015735218,-0.003915812,-0.07301111099999999,-1.826000916,-0.16836612899999998,0.054133043,0.00973161,-0.099250572,0.067088489,-0.098558925,0.025082238,-0.032913861,0.027545461,-0.173567683,-1.585650944,-2.066350888,0.665608126,1.315719665,-8.984364507,-7.497812592000001,-9.552730087,-11.35117878,-8.256558372999999,-8.263542702,-7.296778802,-2.43883982,-11.25151252746582,-13.884977340698242,-9.112217903137207,-11.15971851348877,-12.050154685974121 -2567,2567,R159D,0.003476165,0.042122712,-0.658410457,-1.8083257030000002,-2.750766539,-0.10758727900000001,0.048747947,-0.041795618,-0.151335045,0.029341792999999998,0.05490363,-0.353493241,-0.963327673,-1.549782175,-2.06686923,-2.44677643,-3.054756647,1.5752823480000002,0.842614192,-10.18176155,-10.512965,-10.97441766,-11.71783959,-9.322845688,-8.380739822,-6.9451951229999995,-2.863109062,-11.539998054504395,-12.80462646484375,-9.850929260253906,-11.721895217895508,-12.82751750946045 -2568,2568,R159G,-0.002218888,-0.006202985,0.0025941560000000002,-1.029913777,-2.092619471,-0.06335971,0.021176285,-0.02561406,-0.047382213,-0.00142319,-0.010982779,0.006981065,-0.0017927529999999998,-0.535363936,-1.5244636180000002,-1.7654331140000001,-2.419805827,1.808348249,1.4770453940000001,-10.89755506,-7.339528839,-11.07260362,-12.56170866,-12.214936,-11.29899818,-8.068370701000001,-3.500316106,-10.584701538085938,-11.787983894348145,-7.630013465881348,-12.161323547363281,-11.588939666748047 -2569,2569,R159F,0.146300946,0.054935495,0.140125367,0.070928387,-1.18597189,0.0075222330000000006,0.20050093300000002,0.09210095800000001,-0.569334847,-0.013684553,0.123555543,0.056681224,0.22356950899999997,0.021205283,0.120651491,-1.38607859,-0.9858651890000001,0.7534246059999999,1.3321743129999999,-12.25968075,-12.29506146,-12.09029714,-13.31502723,-11.73356046,-11.86445745,-7.774148651,-4.1004422289999995,-12.951772689819336,-13.740802764892578,-10.52386474609375,-13.591407775878906,-12.838462829589844 -2570,2570,R159I,-0.172504477,-0.10268725,-0.074923104,-0.075693857,-1.4150535880000001,0.074875835,-0.147759091,-0.197249862,-0.44439611100000004,0.052292674000000004,-0.257667174,0.013632821000000002,-0.163479028,0.10999080300000001,-0.261378516,-1.471250199,-1.3588569769999999,0.47838392399999996,1.311922174,-11.23793614,-11.674665699999998,-11.8942569,-12.93797182,-9.853796165,-9.828990105,-7.114581332,-3.1663546489999996,-11.754158020019531,-14.42415714263916,-11.111955642700195,-12.437692642211914,-12.69086742401123 -2571,2571,R159H,0.038028575,0.020620135,0.011238471000000002,-0.005179846,-0.024222481,0.010654298999999999,0.073903434,0.002153715,-0.031239354,-0.005955111,0.04719538,0.012121103000000001,0.010355839,-0.042974690999999995,0.032614999,-0.021729488999999998,-0.026715472,1.191705043,2.506115455,-5.931717001,-5.950411255,-6.185365845,-7.022521423,-5.826043587000001,-4.674242897,-5.18132903,-2.760801921,-8.338785171508789,-9.915428161621094,-6.080432891845703,-8.889892578125,-8.550886154174805 -2572,2572,R159K,-0.009028911,-0.023887062999999997,-0.023743115,-0.078192129,-0.213063427,-0.082231903,-0.042528469000000006,0.024470647,-0.37184544399999997,0.00265531,-0.050429435999999994,0.081190724,-0.128676954,-0.0029283959999999998,-0.153455862,-0.24841660100000001,-0.17771025199999999,1.590887955,2.182387887,-8.513595859,-6.6457785110000005,-9.147201752,-10.24097353,-7.44688295,-9.087142555,-6.739181677,-2.265574989,-8.504182815551758,-11.312767028808594,-7.644072532653809,-10.4549560546875,-9.805877685546875 -2573,2573,R159M,0.013738743999999999,0.027321752,0.005360126,0.02419171,-1.835369183,-0.123062528,0.025238125,0.002239363,-0.211117899,0.029470264,0.025173239,-0.017187485,0.027907736000000002,0.020221604,0.028161816,-1.165568191,-2.505170174,0.59063464,1.330427803,-10.60933649,-9.401110977,-11.01148328,-12.88050896,-9.669185387,-10.08439388,-8.234130867000001,-4.438849478,-11.306233406066895,-13.79814338684082,-9.78701400756836,-12.205889701843262,-12.525336265563965 -2574,2574,R159L,-0.0338852,-0.039064701,-0.0052510840000000005,-0.069197161,-1.8990577219999998,0.013282291000000002,-0.004527408,-0.063242991,-0.28589517600000003,-0.01133377,-0.066795631,-0.016412201,0.005910033,-0.028147009,-0.11024731199999999,-1.655403626,-2.142711817,0.850632225,1.3232654259999999,-9.01914816,-9.008939041,-9.475481071,-10.54249068,-7.820228462,-8.248601547,-6.9317394320000005,-3.526506195,-9.572630882263184,-12.754634857177734,-8.088302612304688,-10.829428672790527,-11.268440246582031 -2575,2575,R159N,0.064347058,-0.047621030999999994,-0.048171944,0.038834367,-1.158634112,-0.040648237000000004,0.10260546300000001,0.026088653,-0.205514022,-0.018574885,-0.07666717599999999,0.047651908,-0.143995795,0.040181209,0.037487525,-0.624317755,-1.692950468,0.677908692,1.403005034,-9.233042659,-8.491120781000001,-10.86623704,-10.543688699999999,-8.140628365,-8.123538414,-6.973668223,-2.495390487,-10.501240730285645,-12.139768600463867,-8.782461166381836,-11.573585510253906,-10.633113861083984 -2576,2576,R159Q,0.033417452,0.058159924,0.010645542,0.06470611700000001,-0.117895174,-0.015205783,0.027813917,0.039020986,-0.06537309,0.063450975,0.052868872000000004,-0.00156082,0.022851903,0.064207447,0.065204786,-0.136088619,-0.099701728,1.398049603,2.2762375230000003,-5.3583767589999995,-3.935880661,-6.341570549,-6.797848366,-4.913378532,-4.803205688,-4.807205271,-2.147814404,-7.589520454406738,-10.33627986907959,-5.679817199707031,-9.451444625854492,-8.478302955627441 -2577,2577,R159P,-0.006923264,-1.343820663,-1.6551942659999999,-1.8226595230000002,-2.195801354,-0.042590282,0.029434187999999997,-0.043280715,-0.296960323,-1.331036313,-1.356605012,-1.450403254,-1.8599852769999998,-1.585994348,-2.059324697,-1.7820033069999999,-2.6095994,4.390451871000001,2.459729036,-11.83971781,-10.84034904,-11.43172881,-12.65912663,-12.61056439,-11.65682016,-9.183697047,-5.372069978,-12.067169189453125,-15.191991806030273,-10.589847564697266,-15.346041679382324,-15.667285919189453 -2578,2578,R159S,-0.025436437000000003,0.008900098,0.0069144459999999994,-0.0009096839999999999,-0.47621861200000004,-0.024304113999999998,-0.03473233,-0.016140543,-0.27736646600000003,-0.000932283,0.018732479,0.004165614000000001,0.009663277,0.008515159,-0.010334527,-0.385594965,-0.566842259,0.626323886,1.453160789,-7.431824477,-6.534859572999999,-7.154044098,-9.169239365,-7.3385028310000004,-6.962476517000001,-6.851931594,-2.126348867,-9.982665061950684,-11.763711929321289,-8.427244186401367,-10.781917572021484,-10.907320022583008 -2579,2579,R159T,-0.027211309,0.00382007,0.02618152,0.022318705,-0.293486986,0.029490659,-0.009337243,-0.045085375,-0.172423615,0.033378944,-0.025738804,0.057184900000000004,-0.004821860999999999,0.042994483,0.0016429270000000002,-0.20256715600000003,-0.384406815,1.244270113,2.034478831,-9.118734329,-7.468052482999999,-8.486753928999999,-11.49363973,-9.421552887,-8.723672615,-7.2112169889999995,-2.496908887,-10.454988479614258,-13.35216236114502,-8.696410179138184,-11.539823532104492,-11.35373306274414 -2580,2580,R159W,-0.021042252999999997,0.021291951,0.01241816,0.009298701,-1.56451437,-0.008446434000000001,-0.011811265,-0.03027324,-0.142589896,0.066272912,-0.023689011,0.04562425,-0.020787931000000003,0.068526283,-0.049928880999999994,-1.572108371,-1.556920369,0.46587897799999994,1.307066499,-11.35921426,-11.56165385,-11.27827748,-12.56290557,-12.03142344,-9.361810951,-8.951126341,-4.610138605,-11.10606575012207,-14.0447416305542,-10.761927604675293,-12.142847061157227,-12.756623268127441 -2581,2581,R159V,-0.022112762999999997,-0.004521954,-0.004261753,0.032257454,-1.5021838980000002,0.016255024,0.011722264,-0.05594779,-0.01876313,0.030453944,-0.039497851,0.000432145,-0.00895565,0.02930425,0.035210657,-1.27886862,-1.725499176,0.6726552090000001,1.3316622329999999,-9.958154842999999,-9.42711216,-10.2285022,-11.58786279,-9.314030937,-9.233266121,-7.054396529,-1.9378355719999998,-11.062724113464355,-14.769126892089844,-9.8712158203125,-11.98910903930664,-12.094100952148438 -2582,2582,R159Y,-0.036953786,-0.030407612,-0.018138127,-0.007278884,-1.576523906,-0.081381179,-0.054220714,-0.019686857,-0.428601844,-0.11567409199999999,0.054858869000000005,-0.024434521,-0.011841731999999999,-0.041926303,0.027368536000000002,-1.6291166380000002,-1.523931173,0.7953359729999999,1.318408427,-12.4374916,-13.39978756,-13.73899608,-13.61253504,-11.48891695,-9.947222343,-8.265361996000001,-4.581534543,-11.71713638305664,-12.697327613830566,-9.395545959472656,-12.346748352050781,-11.944754600524902 -2583,2583,L160A,0.027406827,0.00318338,-0.009497183000000001,-0.007459671,-0.20360832,0.009191616,0.053186612,0.001627041,-0.007138210999999999,0.031725311,-0.025358551,0.019343371,-0.038337736000000004,-0.028661322000000003,0.013741981,-0.18373275,-0.223483889,1.4723182209999999,2.208962197,-9.627284598,-9.557653595,-9.578898613,-9.436677498,-11.97117282,-7.592020462000001,-6.4314914739999995,-2.943898503,-9.241448402404785,-12.957926750183105,-10.819074630737305,-10.31831169128418,-12.745553970336914 -2584,2584,L160C,-0.016330782,-0.048708549000000004,-0.024557762,-0.056976938,-0.091992954,0.115533916,-0.004382021,-0.028279542999999997,-0.007044381,-0.046933944000000005,-0.050483154,-0.019849968,-0.029265556,-0.08890388800000001,-0.025049987000000003,-0.14081137900000001,-0.043174529,1.538648525,2.323131466,-9.786634557000001,-10.7983765,-8.938656822,-11.45994267,-11.84915794,-5.887038849,-6.668783029,-4.078032847,-8.172476768493652,-14.258971214294434,-11.478394508361816,-11.087912559509277,-14.084487915039062 -2585,2585,L160E,-0.001251956,-0.054386705,-1.09653147,-1.935660269,-2.544298692,-0.066568312,0.053292472,-0.055796383,-0.029958389,2.3100000000000002e-05,-0.108796509,-0.823026322,-1.370036618,-1.90911358,-1.9622069569999998,-2.140302118,-2.948295266,3.422476863,2.079461125,-12.86631747,-12.43247539,-12.32604844,-14.11301208,-15.0241438,-10.43590766,-8.249225809,-5.79739118,-13.976066589355469,-18.133743286132812,-13.159627914428711,-13.75257682800293,-17.057838439941406 -2586,2586,L160D,-0.05402176,-0.105071612,-0.8064515640000001,-2.2248481140000003,-2.836727602,-0.06641649599999999,-0.042430262,-0.06561325700000001,-0.020231871000000002,-0.136840518,-0.073302706,-0.317309701,-1.295593427,-1.500306973,-2.949389255,-2.539609985,-3.1338452180000003,1.556864333,0.8495376809999999,-14.66176838,-15.20248042,-13.801995000000002,-15.44929353,-16.78318984,-12.07188309,-9.524716155,-7.845160433999999,-14.396533966064453,-17.701101303100586,-14.600781440734863,-14.600968360900879,-17.672765731811523 -2587,2587,L160G,-0.03006907,-0.015225293,0.00706394,-1.256283636,-2.25622662,-0.04094174,0.0028218490000000004,-0.062959988,-0.066827684,-0.003770238,-0.026680347000000004,0.029104475,-0.014976596000000002,-0.7886643,-1.723902971,-2.037492964,-2.474960276,1.9697112209999998,1.4478640719999998,-14.21309673,-14.50839871,-13.43961076,-15.26296598,-16.30214053,-11.55236767,-9.330793128,-7.35093058,-10.95448112487793,-16.044734954833984,-12.7409029006958,-13.373567581176758,-15.799440383911133 -2588,2588,L160F,0.00864185,-0.016097075,0.012485343000000001,-0.016523232,-0.571760779,0.030664561,0.043449811,-0.026166112000000002,0.025545592000000002,-0.03204472,-0.00014943,0.003176987,0.021793697999999997,-0.075611033,0.042564569000000003,-0.5420424420000001,-0.601479115,1.411205759,1.7556639859999998,-7.784257086,-8.054141212000001,-6.199143089,-10.04012254,-8.976743782,-5.651134804,-5.828534096,-2.346543718,-9.229251861572266,-13.676348686218262,-9.668231964111328,-10.57634449005127,-10.292421340942383 -2589,2589,L160I,-0.022238085,-0.024254286,0.028413255,-0.02777693,-0.040497089,0.135072009,-0.018657061000000003,-0.025819107999999997,-0.039166391,-0.015334958000000001,-0.033173614,0.066904283,-0.010077774,0.018206967,-0.073760826,0.026237833999999998,-0.10723201199999999,1.14065731,2.699438039,-5.3139079360000006,-4.470258972,-5.533962959,-6.226030708,-6.798153778,-3.5411332630000003,-5.057680982,-0.982836658,-8.943950653076172,-12.564321517944336,-7.947072505950928,-10.324803352355957,-9.996138572692871 -2590,2590,L160H,0.049192075999999994,0.062327627999999996,0.055868585,-0.029899812999999997,-1.822190357,0.020167281000000002,0.098444351,-6.02e-05,0.020251261,0.06938911,0.055266145999999995,0.024003315,0.087733855,-0.09099687699999999,0.031197251000000002,-1.4128464790000002,-2.231534235,0.7664278859999999,1.33038868,-12.2227672,-12.62071987,-10.04760716,-14.09740617,-15.20445188,-9.143650925,-6.662650729,-4.962002266,-12.599234580993652,-14.99267864227295,-12.180214881896973,-13.362848281860352,-15.717157363891602 -2591,2591,L160K,-0.031891398,-0.16359192,-1.9684773359999999,-2.190818654,-2.626606882,0.046964657,0.00126631,-0.065049105,-0.064807977,-0.077876517,-0.249307323,-2.04328294,-1.8936717319999998,-2.226280212,-2.155357095,-2.311340714,-2.94187305,0.48810381700000005,-0.169310472,-13.58613826,-14.43279289,-12.58210751,-14.52227884,-14.94833145,-11.44518063,-9.204322665,-7.241744587,-14.474514961242676,-17.277875900268555,-13.217874526977539,-14.75469970703125,-16.462284088134766 -2592,2592,L160M,0.053924209,0.039047466,0.033406332000000004,-0.00713344,-0.16312733699999998,0.058739464000000005,0.098752245,0.009096173,-0.013715702,0.019083992,0.05901094,0.00902616,0.057786502999999996,-0.027520061000000002,0.013253181999999999,-0.16942084,-0.156833834,1.1081098809999999,1.9175844930000001,-5.492166605,-5.508792099,-5.766561501,-6.557824912999999,-5.000112801,-4.62754171,-5.129390433,-2.383283309,-7.776867866516113,-10.875265121459961,-7.344358921051025,-9.199514389038086,-8.451604843139648 -2593,2593,L160N,-0.078962771,-0.10065803400000001,-0.026715061000000002,-0.099119234,-1.9060736040000001,0.107774664,-0.03374028,-0.12418526199999999,-0.068073365,-0.133006247,-0.06830982,-0.091766236,0.038336114,-0.132450675,-0.065787793,-1.572898835,-2.239248372,1.151208795,1.359523324,-11.29894044,-11.83654588,-9.9533283,-13.32575392,-13.22144315,-8.157630928,-7.066454711,-5.323084344,-11.056928634643555,-15.195693969726562,-11.686628341674805,-11.766312599182129,-14.104637145996094 -2594,2594,L160Q,0.08811052300000001,-0.005413103000000001,0.008325991999999999,0.045480140999999995,-1.9256386580000002,-0.05662399,0.139200348,0.037020698,-0.050846962999999995,-0.005092839,-0.005733367,-0.050849930999999994,0.06750191400000001,0.008651014,0.082309267,-1.777545554,-2.073731762,0.6182098570000001,1.305969224,-9.856484186,-10.73331866,-9.268839737,-10.78133125,-10.66775456,-7.83117672,-6.830532487,-4.645871965,-10.845474243164062,-15.815267562866211,-10.265438079833984,-11.619977951049805,-14.880826950073242 -2595,2595,L160P,-0.003801273,-0.015809232,0.015403106000000001,-0.9296758620000001,-1.980249427,-0.04100322,0.031670754,-0.039273299,-0.037517363,-0.013398549,-0.018219914,-0.00045552300000000005,0.031261734,-0.447670996,-1.411680728,-2.1668727569999997,-1.793626096,1.660382438,1.335879095,-12.25372011,-13.57795429,-12.48347221,-14.93040726,-12.17743493,-8.099331871,-6.478473452,-2.63249621,-10.961840629577637,-14.932088851928711,-9.833553314208984,-11.319168090820312,-13.440658569335938 -2596,2596,L160S,0.001387136,-2.7899999999999997e-05,-0.023298053,-0.013600556000000001,-0.219697753,0.027127415,0.020343581,-0.01756931,-0.012158391999999999,0.011983863999999999,-0.012039713,-0.017045398,-0.029550708,-0.045515802,0.01831469,-0.165666882,-0.273728623,1.417606837,2.164073798,-7.6387338410000005,-6.493185112000001,-7.946908791,-9.210125999,-9.934336006,-4.6091132969999995,-4.423453778,-3.0177352930000003,-7.43565034866333,-10.071104049682617,-10.193092346191406,-8.817303657531738,-10.049721717834473 -2597,2597,L160R,-0.03361549,-0.837751162,-1.882843034,-2.1710204109999998,-3.3928570239999996,0.0070047009999999995,0.020475862,-0.087706842,-0.041744426,-0.67056515,-1.0049371740000002,-1.909453525,-1.8562325430000002,-2.0924507969999997,-2.249590025,-2.84651808,-3.939195967,2.951804427,0.990794217,-12.70903158,-13.25827647,-11.79646166,-13.49984899,-14.61621581,-10.37435497,-7.581360097999999,-4.490438877,-13.943889617919922,-15.379409790039062,-12.494182586669922,-13.532718658447266,-15.835454940795898 -2598,2598,L160T,0.001835825,0.02036359,0.039080058,0.031371965,-0.27647592,0.04679359599999999,0.002682849,0.000988801,-0.110502912,0.034800015,0.005927164,0.08209404599999999,-0.00393393,0.036596627,0.026147302999999997,-0.217470238,-0.335481601,1.4159215669999998,2.135894609,-10.1569795,-9.967608986,-10.78371256,-10.98184974,-11.58865354,-7.463072692999999,-6.444531636000001,-4.104247322,-9.999116897583008,-14.48801040649414,-9.564177513122559,-11.42938232421875,-13.170498847961426 -2599,2599,L160W,-0.043526455,-0.131249371,-1.696969041,-2.312522247,-3.154767154,0.023982412999999998,0.008723746,-0.095776655,-0.068691578,-0.038339498,-0.22415924399999998,-1.795340474,-1.5985976080000002,-2.330520264,-2.29452423,-2.716610761,-3.592923546,0.526994339,-0.044521729,-13.09213344,-13.98359287,-11.61586096,-14.70507079,-14.26106961,-10.89507295,-8.63791186,-6.545641297,-13.431525230407715,-16.608436584472656,-12.619502067565918,-14.939395904541016,-16.457294464111328 -2600,2600,L160V,-0.018478405,-0.015216865,-0.025935664,-0.042705096,-0.052868258,0.14753859800000002,-0.012886700000000003,-0.024070109,-0.017423207,-0.003132138,-0.027301592000000003,-0.029038582,-0.022832745,-0.07003190200000001,-0.015378289,-0.044533582,-0.061202933,1.306301299,2.40719048,-6.454776016,-6.050416077,-5.953768822000001,-7.709530937,-8.619635642999999,-3.940528603,-3.73514128,-0.82363787,-7.93544340133667,-13.53683090209961,-8.72120189666748,-9.14487075805664,-10.334283828735352 -2601,2601,L160Y,-0.056448264000000005,0.00716131,-0.9886035590000001,-2.018092101,-2.876429349,-0.029792144,0.008754434,-0.12165096199999999,-0.013920123999999999,0.044579035999999995,-0.030256417,-0.7041842840000001,-1.273022834,-2.142454061,-1.89373014,-2.528544559,-3.2243141389999996,1.7458827319999999,0.6976246709999999,-12.39292286,-13.38622007,-10.50140802,-13.9722675,-14.02762264,-10.07709606,-7.313237053,-4.647974201,-12.039148330688477,-15.48199462890625,-11.832944869995117,-12.710179328918457,-14.154916763305664 -2602,2602,D161A,-0.10834899,-0.061708135,-0.054588507,-0.047746776,-1.7242390669999998,0.075072134,-0.085812963,-0.130885017,-0.007822676,-0.033517133,-0.08989913699999999,-0.043470657999999995,-0.065706355,-0.031212797,-0.06428075400000001,-1.589715114,-1.858763019,0.629716331,1.312791792,-9.398640111,-8.97341468,-9.096185973999999,-10.9373978,-8.487806137,-9.498395966,-7.543120387,-1.995660061,-10.295056343078613,-14.067972183227539,-11.101105690002441,-12.77806282043457,-12.55452823638916 -2603,2603,D161C,-0.09829915300000001,-0.02249329,-0.015560947,-0.131804351,-1.714345305,0.08841106800000001,-0.066839766,-0.12975854,0.004802231,0.010908957,-0.055895535999999996,0.033313033,-0.06443492599999999,-0.063589881,-0.20001882,-1.788621834,-1.640068776,0.8861056270000001,1.316093513,-15.12244929,-16.733535999999997,-15.05192912,-15.76705503,-13.16540733,-14.89431895,-9.889363994,-6.146411962,-14.60745620727539,-15.174476623535156,-13.665573120117188,-16.087604522705078,-14.617380142211914 -2604,2604,D161E,-0.062340605,-0.032277667,-0.064318609,-0.016074263999999998,-0.9411997740000001,0.08552439,-0.02223435,-0.10244686,-0.032761795,-0.049393072999999996,-0.01516226,-0.06266999,-0.065967228,-0.012927001,-0.019221527,-0.9949746979999999,-0.88742485,0.646441054,1.3506049409999998,-7.835697556,-9.157033813,-7.098443764,-7.385292037999999,-6.507110626,-9.030607536,-5.515764832,-2.081012008,-8.095904350280762,-11.63658332824707,-8.063754081726074,-8.63050651550293,-9.241046905517578 -2605,2605,D161G,-0.070989359,-0.036877915,-0.072913283,-1.836174552,-3.112543508,0.118624613,-0.046324672000000004,-0.09565404599999999,-0.014571361000000001,-0.038442877,-0.035312953,-0.051654605,-0.09417196,-1.589016789,-2.083332314,-2.637730008,-3.587357007,0.762656806,0.701592952,-12.32699115,-10.29972762,-11.62486637,-14.48310667,-10.74828979,-14.47896528,-7.890100144,-2.33064941,-10.25626277923584,-13.346750259399414,-11.03773021697998,-12.488948822021484,-13.4048433303833 -2606,2606,D161F,-0.105109097,-0.06257547200000001,-0.070186455,-1.84345872,-2.7461425139999998,0.10926626699999999,-0.048536830999999996,-0.161681363,-0.045483401,-0.050100374,-0.075050569,-0.106545536,-0.033827373,-1.604248747,-2.082668693,-2.453092861,-3.0391921660000003,1.0027090909999998,0.7197993340000001,-16.42005556,-15.78095635,-17.21906222,-16.02111028,-16.17914095,-16.90000802,-9.307677933999999,-4.814406953,-15.177318572998047,-17.61717987060547,-13.202485084533691,-15.478147506713867,-16.855464935302734 -2607,2607,D161I,-0.048420987,-0.039690502,-0.032382938,-0.995981875,-2.7548884769999997,0.063070393,-0.020757769,-0.076084205,-0.052951442,-0.09787863599999999,0.018497632,-0.007170228000000001,-0.057595647,-0.564821618,-1.427142132,-2.63709087,-2.872686083,0.927171874,0.893497188,-13.79137438,-14.17358899,-13.99844852,-13.18120758,-13.3242634,-14.27936342,-8.397130688999999,-3.4725668489999997,-13.436811447143555,-16.303081512451172,-12.765287399291992,-15.440316200256348,-14.777892112731934 -2608,2608,D161H,-0.095353583,-0.065950842,-0.058164247,-0.024234272999999997,-1.928225329,0.053954759000000005,-0.058767390999999995,-0.131939774,0.062654592,-0.060229229,-0.071672455,-0.063000175,-0.053328318,0.021259421,-0.069727966,-1.600282847,-2.25616781,0.69345813,1.316599517,-12.87713665,-13.967882000000001,-11.933867800000002,-13.71345004,-10.81879561,-13.95168781,-8.339767128,-3.318978514,-11.818641662597656,-13.76856517791748,-11.04820442199707,-13.374252319335938,-12.568453788757324 -2609,2609,D161K,-0.12650453,-0.07254445400000001,-0.316735638,-2.316746905,-2.460173728,0.09502537300000001,-0.09578541900000001,-0.15722364,-0.082168586,-0.064719543,-0.080369364,-0.178931024,-0.454540251,-1.5971068000000002,-3.036387009,-2.550686264,-2.369661191,1.1887945309999999,0.743321751,-13.23109526,-14.49564706,-13.08944471,-14.46954542,-10.31582945,-13.78500966,-8.284320425,-2.3216394819999997,-12.227481842041016,-16.260730743408203,-12.730371475219727,-14.535932540893555,-14.265807151794434 -2610,2610,D161M,-0.156952801,-0.118727154,-0.09845992,-0.171500113,-1.9261155030000001,0.087543348,-0.11565978199999999,-0.19824582,0.044812985,-0.053757877999999995,-0.18369643,-0.097229581,-0.099690258,-0.10402619,-0.238974035,-1.889201224,-1.9630297819999998,0.983920804,1.3155101740000001,-15.51436799,-15.83515818,-15.97575707,-15.192527499999999,-13.30160258,-17.2667946,-9.182369938999999,-5.114383022,-14.371648788452148,-16.714712142944336,-13.736987113952637,-14.41910457611084,-16.29448127746582 -2611,2611,D161L,-0.089750285,-0.06971346,-0.224141808,-1.8933294440000001,-3.35120605,0.051837941,-0.089296739,-0.09020383,0.002524325,-0.021009012999999997,-0.11841790699999999,-0.149845863,-0.29843775300000003,-1.666042222,-2.120616666,-3.041695375,-3.660716724,1.026334181,0.714551904,-13.68521433,-14.11459354,-14.47441222,-13.95612801,-12.00477789,-13.87616,-8.451608366,-2.516541712,-13.476788520812988,-17.20859718322754,-13.085199356079102,-14.996844291687012,-16.110397338867188 -2612,2612,D161N,-0.07002509,-0.00172883,-0.080452993,0.001966741,-0.6219629170000001,0.11120781199999999,-0.008209159,-0.13184102,0.042131012,-0.015790632,0.012332972,-0.019798225,-0.141107761,-0.033083609,0.037017091,-0.662057539,-0.581868295,0.896732779,1.449667508,-8.572680447,-9.59049408,-7.637481316000001,-9.495830977999999,-8.082341492000001,-8.057254372000001,-7.197342792000001,-1.746783276,-8.456204414367676,-10.63612174987793,-7.802677631378174,-8.667909622192383,-8.457460403442383 -2613,2613,D161Q,-0.070759951,-0.056316367,-0.050416548,-0.170371534,-1.8701802109999999,0.048214158,-0.026522888999999997,-0.114997012,0.04172875,-0.04031377,-0.072318964,-0.064401974,-0.036431121000000004,-0.09467968,-0.246063388,-1.7014716580000002,-2.038888763,1.363000051,1.379699534,-12.83102828,-15.19735185,-13.13547095,-12.9504473,-11.39873111,-11.4731402,-6.898414785,-2.1099339440000002,-11.6867094039917,-15.332215309143066,-12.020279884338379,-13.3671875,-13.255141258239746 -2614,2614,D161P,-0.07721476,-1.5536223880000002,-2.194788319,-2.230308746,-3.45690128,0.052037239000000006,-0.035432784,-0.118996735,-0.022434102999999997,-1.584715869,-1.522528906,-2.061816677,-2.327759961,-1.979390102,-2.481227389,-3.0878715260000003,-3.8259310330000003,-0.131189854,-1.005753369,-14.87375725,-15.91686683,-14.39036547,-15.16599724,-14.22465984,-14.67089685,-9.654606453,-5.400574416,-13.589387893676758,-17.79854965209961,-15.066484451293945,-16.241432189941406,-15.927936553955078 -2615,2615,D161S,-0.083540559,-0.057183397999999996,-0.061549994000000004,-0.036778073,-1.313168235,0.130557325,-0.052596211,-0.114484907,-0.034780964,-0.059310894,-0.055055901,-0.049420908,-0.07367907900000001,-0.035981664,-0.037574481,-1.081416951,-1.5449195180000002,0.819974193,1.363870968,-8.806065321,-11.44112521,-7.571183075,-10.11536168,-7.030923386,-7.871733261,-5.605814856,-2.553518119,-10.904447555541992,-14.426177978515625,-10.526978492736816,-12.809014320373535,-12.707618713378906 -2616,2616,D161R,-0.08601113099999999,-0.061761507,-0.705353715,-2.155316755,-2.503933896,0.081029585,-0.057967637999999995,-0.11405462400000001,-0.04435846,-0.052330189000000006,-0.071192825,-0.499644766,-0.9110626629999999,-1.741197385,-2.569436125,-2.5289047559999998,-2.478963035,1.769566793,0.8441862929999999,-12.72638799,-14.34664201,-11.84157831,-13.79447385,-10.46859388,-13.18065192,-7.816632365,-1.5564309109999999,-13.245972633361816,-17.181045532226562,-14.035178184509277,-15.328829765319824,-15.241215705871582 -2617,2617,D161T,-0.08186665,-0.037084608,-0.014758338000000001,-0.034511641,-1.5850553090000001,0.10174064,-0.04860552,-0.115127779,0.005038923,-0.012081682,-0.062087533,0.010669672,-0.040186348,-0.018839507,-0.050183774,-1.5387256930000002,-1.631384925,0.872682338,1.329733117,-10.18597303,-11.43014977,-11.13449303,-9.781840851,-8.862585098,-9.720796387,-6.79781238,-2.851261144,-11.250894546508789,-14.843096733093262,-10.471931457519531,-13.351802825927734,-12.72327709197998 -2618,2618,D161W,-0.019340628999999998,-0.064226418,-0.49690956700000005,-1.822103169,-2.7815416,0.012014423,0.032899655,-0.071580912,-0.027362966000000002,-0.12480377599999999,-0.003649059,-0.333400295,-0.660418839,-1.8307573169999998,-1.813449021,-2.939238741,-2.623844458,1.5104211630000002,0.756367805,-17.14101957,-17.49109698,-16.38699695,-17.52819489,-16.49462246,-17.80418659,-11.04656685,-7.264617223999999,-15.314037322998047,-19.62133026123047,-16.1487979888916,-16.647323608398438,-18.679996490478516 -2619,2619,D161V,-0.12973411699999998,-0.054072317,-0.049243682000000004,-0.051189816,-1.579928924,0.060259904,-0.105485557,-0.15398267699999998,-0.018214266,-0.040467631000000004,-0.067677002,-0.03067208,-0.067815284,-0.017584113000000002,-0.084795519,-1.5729069119999999,-1.586950936,0.71045965,1.319131681,-10.94645488,-10.58341835,-11.06602533,-10.48153832,-10.65123735,-11.95005505,-6.788903743,-2.127282258,-11.671643257141113,-14.985097885131836,-10.993512153625488,-14.417488098144531,-13.508241653442383 -2620,2620,D161Y,-0.05521422,-0.078894651,-0.039304037,-0.9667892309999999,-2.4218407,0.037602272,-0.06381173,-0.04661671,-0.006073731999999999,-0.14061684300000002,-0.017172458999999998,-0.068245314,-0.01036276,-0.575644274,-1.3579341880000002,-1.9271637469999998,-2.916517653,1.850426471,1.448434552,-16.31672933,-16.953608300000003,-17.55546302,-15.32879086,-15.00440263,-16.74138184,-8.463720157000001,-3.436432182,-13.546180725097656,-15.159040451049805,-12.289655685424805,-13.324469566345215,-14.006146430969238 -2621,2621,R162A,0.013039334,0.013666853999999999,-0.006380363000000001,-0.003183783,-2.052036726,0.7106767979999999,0.018282793000000002,0.007795874,0.029035292,0.00876204,0.018571667,-0.016076111,0.0033153859999999996,-0.006572555999999999,0.000204991,-1.874608491,-2.229464961,0.712795762,1.303444692,-13.40647427,-12.78526608,-13.526741399999999,-15.22016901,-12.69214344,-12.80805142,-7.007269452999999,-2.67247687,-12.458392143249512,-13.632664680480957,-8.302604675292969,-12.526130676269531,-14.043002128601074 -2622,2622,R162C,-0.070157827,-0.030887902000000002,-0.004550383,-0.008773342,-1.942558976,0.294017175,-0.071852187,-0.068463467,0.037713558,0.030368741,-0.09214454400000001,0.043769992,-0.052870758,0.043641646,-0.06118833,-1.6810141319999998,-2.204103819,0.5582411860000001,1.305932596,-16.71286543,-16.2110555,-16.72165221,-17.46296417,-17.83572593,-15.33292934,-9.714961215,-6.479640252,-11.6613130569458,-11.889585494995117,-7.635869979858398,-11.152572631835938,-11.496524810791016 -2623,2623,R162E,-0.026155304,-0.027690471,0.018052636,-0.6823396190000001,-2.229220485,0.325070612,0.004625586,-0.056936192999999996,0.004001623,-0.031398702,-0.02398224,0.030851748999999998,0.005253521999999999,-0.38070634600000003,-0.983972892,-2.153409611,-2.305031359,1.436542339,1.319962324,-14.47413447,-16.18828601,-14.014827800000003,-15.10484735,-13.26012266,-13.8025885,-8.150268899,-3.7058631380000002,-14.551525115966797,-16.287992477416992,-9.06556510925293,-12.930473327636719,-14.405540466308594 -2624,2624,R162D,-0.032867459,-0.049416702,-0.030315453,-0.070850244,-1.797269994,0.9484361240000001,-0.012927126,-0.05280779099999999,0.02339357,-0.021328693,-0.07750471,-0.010777568000000001,-0.049853338,-0.068493068,-0.07320741900000001,-1.249650367,-2.344889621,0.8921156020000001,1.354440736,-13.29316224,-14.91927184,-12.23097237,-13.21223911,-12.85721874,-13.24610914,-6.1916967960000004,-3.373588769,-14.159875869750977,-15.765868186950684,-8.481459617614746,-13.323417663574219,-13.883058547973633 -2625,2625,R162G,0.017657807,0.012760522,-0.0034966290000000002,-0.013391633,-1.4602986230000001,0.8099812540000001,0.033011083999999996,0.002304529,-0.000111523,0.007741455,0.017779588,-0.013193773999999998,0.006200516999999999,-0.03013575,0.003352485,-1.238914758,-1.6816824869999998,0.693145977,1.335882679,-15.05448282,-14.13933615,-16.15623193,-15.313985500000001,-16.14182278,-13.52103777,-7.5445291160000005,-3.3465632710000004,-12.277483940124512,-13.892374992370605,-7.9689178466796875,-12.554438591003418,-12.96429443359375 -2626,2626,R162F,-0.010716356000000002,0.005011374,-0.164267481,-2.072544665,-2.76348965,0.08646784199999999,0.058080383,-0.079513094,0.042680999000000004,-0.045508541,0.055531288,-0.104509658,-0.22402530399999998,-1.7072739609999998,-2.4378153680000003,-2.3493153159999998,-3.177663983,0.863764761,0.696101757,-17.78978081,-13.83370365,-17.5888504,-17.4662517,-21.53635898,-18.52373933,-8.652674937999999,-4.4470258419999995,-13.873281478881836,-14.983942031860352,-9.333661079406738,-12.629899978637695,-15.21514892578125 -2627,2627,R162I,-0.036139332999999996,-0.300358296,-2.300576238,-2.2058670780000003,-2.7752930389999997,0.027927163999999997,-0.05733712,-0.014941545,0.086046495,-0.22934022899999998,-0.371376362,-2.279950755,-2.32120172,-2.422461728,-1.989272428,-2.520435039,-3.030151038,0.185996238,-0.419919745,-16.76736429,-15.49182351,-17.73335866,-17.74301726,-16.07133646,-16.79728556,-8.60904314,-4.458766602,-13.40318775177002,-13.963529586791992,-9.232911109924316,-11.732888221740723,-12.971327781677246 -2628,2628,R162H,0.042839562000000005,0.022684594,0.02638014,-0.016996149,-0.45436417799999995,1.064041417,0.056986913,0.02869221,-0.061643496,0.034096613,0.011272573999999999,-0.005561959,0.058322238,-0.03060076,-0.003391537,-0.413989149,-0.494739207,1.146801791,1.6836855480000001,-8.012232256,-7.638493156,-7.145290695,-8.13841629,-10.35576485,-6.783196289,-6.692561968,-2.320008398,-9.075429916381836,-10.792516708374023,-5.873689651489258,-9.81178092956543,-8.96152400970459 -2629,2629,R162K,-0.022047389,0.027426871000000002,-0.022070713,-0.018237895,-1.553189419,0.11410754199999999,-0.014212108999999999,-0.029882667999999998,-0.014294336000000001,0.024698839,0.030154902,0.004345422,-0.048486848,-0.025191607,-0.011284183,-1.530919909,-1.5754589280000002,0.605586321,1.313882773,-12.75921038,-13.62157138,-14.00103527,-12.04714088,-12.87576459,-11.25053979,-8.516844276,-4.278501193,-10.862300872802734,-12.429643630981445,-7.002816200256348,-10.589873313903809,-11.050199508666992 -2630,2630,R162M,0.055510548,0.034168218,0.026430682,-0.675194757,-2.409700729,0.193809325,0.043258549,0.067762547,-0.02366194,0.00485589,0.063480546,-0.050773288,0.103634651,-0.518582831,-0.8318066829999999,-2.07895414,-2.740447318,1.672948852,1.359658812,-16.0001423,-13.50776031,-17.27514378,-17.16194892,-16.62809741,-15.42776106,-8.148495814,-5.105593839,-14.273764610290527,-14.831595420837402,-9.337519645690918,-12.234066009521484,-14.678385734558105 -2631,2631,R162L,-0.016498782,-0.0027111809999999996,-0.029340266,-1.467066735,-2.600935808,0.11001835300000001,0.004269526,-0.037267088999999996,0.026042311000000002,0.003388197,-0.008810559,-0.057826632,-0.000853899,-1.2147468000000001,-1.71938667,-2.027678221,-3.1741933939999996,2.457822576,1.645030835,-15.37390706,-13.81648914,-16.53858141,-16.99187341,-14.84177122,-14.68082011,-8.198210749,-5.142809617,-12.397004127502441,-13.108220100402832,-8.002947807312012,-11.006710052490234,-13.076959609985352 -2632,2632,R162N,0.07267294099999999,0.08390529099999999,0.03837183,0.016621897,-0.318084574,1.1137175,0.037385052,0.10796083,0.044287161,0.076755006,0.091055576,0.059341982,0.017401677,0.014248671999999999,0.018995121,-0.243876697,-0.39229245100000004,1.0163317490000001,1.7610112969999998,-13.97357111,-14.85935603,-13.96016421,-13.4612851,-15.45265293,-12.13439729,-7.7140292189999995,-2.21911816,-11.598609924316406,-14.053169250488281,-7.402657508850098,-11.30337905883789,-11.899065971374512 -2633,2633,R162Q,0.048484828,0.056271311,0.066502918,0.000373536,-0.955581138,0.523068075,0.046162983,0.050806672000000004,-0.026851623999999998,0.030533277999999997,0.082009343,0.071573725,0.06143211,0.012528072,-0.011781001000000001,-0.935905007,-0.9752572690000001,0.643579035,1.354795011,-10.4977702,-10.75079803,-11.21688216,-10.59140076,-10.89104184,-9.038728203,-7.557819222999999,-3.804060528,-11.236153602600098,-13.017807006835938,-7.043002128601074,-10.445891380310059,-11.469833374023438 -2634,2634,R162P,-0.028398487000000004,-1.4553847119999999,-1.8272121,-1.9387009030000002,-2.4326896280000003,0.090456613,0.017893353,-0.074690327,-0.041242007000000004,-1.531898699,-1.378870724,-1.847033163,-1.807391037,-1.767695386,-2.109706419,-2.564638701,-2.300740554,-0.071866542,-0.97614785,-15.42498967,-16.76628132,-15.59979405,-16.29042326,-12.97398383,-15.49446588,-8.319902109,-3.7203928439999996,-12.93420696258545,-12.412013053894043,-10.2135591506958,-14.060894966125488,-15.804534912109375 -2635,2635,R162S,-0.000719945,0.013098363,-0.010862563,-0.027030982000000002,-0.46063335899999996,1.129394537,0.000226049,-0.001665939,-0.004210231,0.027935047,-0.0017383210000000001,-0.013147242,-0.008577884000000001,-0.016714365,-0.037347597999999996,-0.38124478799999995,-0.54002193,1.5632782090000001,1.9839067259999998,-13.91110369,-14.34488907,-13.543749400000001,-15.36910068,-13.64308521,-12.65469411,-6.901898123,-2.658960166,-11.627676010131836,-12.91468620300293,-7.602204322814941,-11.593162536621094,-11.594786643981934 -2636,2636,R162T,-0.052615163,-0.031957021,-0.021453833999999998,-0.031577131,-1.077646983,0.090227991,-0.075330358,-0.029899968,0.005899958,0.03560436,-0.09951840099999999,0.001390903,-0.04429857,0.005121373,-0.068275634,-0.9240022640000001,-1.231291701,0.761670471,1.37192277,-14.19588387,-14.10910554,-13.94850131,-15.59345864,-13.69940262,-13.62895126,-7.791255168999999,-3.157326825,-12.228270530700684,-13.41120433807373,-7.522284984588623,-11.395760536193848,-12.456554412841797 -2637,2637,R162W,-0.009361966999999999,-0.017632794,-1.308938288,-1.876576085,-3.042912059,0.037447685,0.033261847000000004,-0.051985780999999995,-0.008032719,-0.023586776,-0.011678812,-1.3501507019999999,-1.2677258740000001,-1.969782929,-1.783369241,-2.766726245,-3.319097873,2.651085433,1.138548254,-16.41846195,-16.56449343,-15.56493394,-15.93522244,-19.720653600000002,-14.30700634,-9.487746595,-6.084533048,-12.330349922180176,-15.097017288208008,-9.674783706665039,-12.348806381225586,-14.144116401672363 -2638,2638,R162V,-0.032957522999999996,0.001723938,-1.201424467,-2.102820185,-3.188958023,0.061281703,-0.008911453,-0.057003592,0.013970781000000002,-0.009716663,0.013164539,-1.12769904,-1.275149893,-1.9581846330000001,-2.247455736,-2.5613079219999997,-3.816608123,2.366014195,0.9963043340000001,-14.71488306,-14.16886832,-16.37949016,-15.90224812,-12.93665727,-14.18715143,-7.610790048999999,-3.7767698189999996,-13.476152420043945,-13.641853332519531,-9.366960525512695,-13.378097534179688,-13.906856536865234 -2639,2639,R162Y,-0.054955,-0.017161983999999998,-0.627198429,-2.4432241969999997,-2.86213516,0.099495989,-0.036273625,-0.073636375,0.043129197,0.001927318,-0.036251285,-0.376340966,-0.8780558909999999,-2.162304615,-2.724143779,-2.5613079219999997,-3.162962398,1.3687651369999998,0.65209001,-16.37081881,-14.57087296,-17.42459633,-15.58610139,-20.5867116,-13.68581178,-8.289931244,-3.983666061,-12.357912063598633,-14.078526496887207,-8.53294563293457,-12.092503547668457,-13.447562217712402 -2640,2640,W163A,-0.022004943,-0.004331649,-0.03407479,-0.045689653,-0.356231928,-0.043333530999999995,-0.020800868,-0.023209017000000002,0.038732735,-0.021012759,0.012349461,-0.012380216000000001,-0.055769364,-0.056812866,-0.034566439,-0.31722648,-0.39523737600000003,1.52873063,2.0536563919999997,-5.2469057569999995,-6.412155113,-3.9188149639999996,-5.111279091,-5.065495285,-5.726784332,-5.203526917,-2.529995059,-7.450700759887695,-7.701000213623047,-3.78118634223938,-4.072653293609619,-8.223129272460938 -2641,2641,W163C,-0.01488316,-0.020287351000000002,-0.021445093999999998,-0.024422869,-0.266007873,-0.03436324,-0.009480909000000001,-0.020285411,0.044559034000000004,-0.061874056,0.021299354,0.008430591,-0.051320779000000004,-0.05777657,0.008930832,-0.23968962100000002,-0.29232612399999996,1.275254113,1.9306252169999998,-7.3034675810000005,-8.598191864,-6.12808728,-6.065895821,-7.846106689,-7.879056252000001,-6.819717847000001,-4.539242748,-9.106090545654297,-7.087743759155273,-4.849233150482178,-6.0383405685424805,-7.690587520599365 -2642,2642,W163E,-0.009820251,-0.012109613,-0.008143561,-0.001248281,-0.325154719,-0.011510043999999999,-0.014450605,-0.005189895999999999,0.039222532000000004,0.002419241,-0.026638467000000002,-0.029592444,0.013305322,-0.030908188,0.028411627000000002,-0.26668178800000003,-0.38362765,1.305234445,1.928627581,-5.828521883,-6.783417137000001,-5.334286186,-5.829899772999999,-5.680940575,-5.5140657420000005,-6.3835177839999995,-2.409447493,-9.39457893371582,-8.829449653625488,-4.638372421264648,-4.338207721710205,-8.862874984741211 -2643,2643,W163D,0.014823731000000001,0.00625269,0.0192872,-0.01604435,-0.6581217979999999,0.078159003,0.032444022999999995,-0.002796561,0.055799854,0.007437893,0.0050674859999999995,0.002468905,0.036105494,-0.013324188,-0.018764511,-0.5049814779999999,-0.8112621179999999,0.86310733,1.487320613,-4.966223427,-6.274083191,-2.7418322139999995,-4.654009727,-6.670378922,-4.49081308,-5.696116073,-0.891508741,-8.102059364318848,-8.412101745605469,-4.515535354614258,-4.385259628295898,-8.561837196350098 -2644,2644,W163G,-0.0032956659999999996,-0.007736018000000001,0.0087194,-0.011963573,-0.720388025,0.000903972,-0.006785942,0.000194611,0.019992153999999998,-0.023939266,0.008467231,0.010092004,0.007346796,-0.027694276,0.00376713,-0.5815482129999999,-0.859227837,0.993326375,1.516977071,-5.753455768999999,-7.0661117860000004,-4.451125275,-5.6176070629999995,-5.544435837000001,-6.087998886,-5.6725333860000005,-0.674048236,-9.293166160583496,-7.7582855224609375,-5.767453193664551,-7.244369983673096,-9.417458534240723 -2645,2645,W163F,-0.02609923,-0.049511665,-0.043193453,-0.005615639,-0.20442420000000003,-0.044948040999999994,-0.044180152,-0.008018306999999999,0.012592403,-0.069898301,-0.029125027999999997,-0.056401127,-0.029985779,-0.050391677999999995,0.039160401,-0.161255924,-0.247592476,1.33500888,2.092666864,-3.832996361,-5.08917205,-2.953329224,-3.087899834,-3.566759537,-4.467821159,-3.507711675,-1.6923281980000002,-5.9326677322387695,-5.378423690795898,-1.5148134231567383,-1.7707513570785522,-4.763967990875244 -2646,2646,W163I,0.05590327900000001,0.031102247000000003,0.026509827000000003,-0.018841289,-0.058474829000000006,-0.018283128,0.059773815,0.052032742,0.0037742509999999997,-0.013445883,0.075650377,-0.007776873,0.060796526,-0.06694982599999999,0.029267248,-0.13439632,0.017446661999999998,1.4942264840000001,2.3188995169999997,-3.313435425,-4.644261932,-1.841537735,-2.138367195,-4.462929077,-3.480081184,-3.5614123189999995,-0.858343768,-3.382845878601074,-3.291856050491333,-1.7499899864196777,0.43470144271850586,-3.7482118606567383 -2647,2647,W163H,0.043102825,0.015131977,-0.021810552999999996,-0.003039665,-0.34393850000000004,-0.039147404,0.070472466,0.015733183,0.034037449,0.029690022000000003,0.000573932,-0.07903375,0.035412645,-0.028831303,0.022751973999999998,-0.340479149,-0.34739785,1.478403149,1.961890967,-4.071987851,-5.530912796,-3.886641434,-3.922721878,-3.6058634639999996,-3.413799683,-4.352410154,-2.792137276,-6.67064905166626,-6.001123428344727,-3.3946683406829834,-3.3200249671936035,-6.518551349639893 -2648,2648,W163K,0.0036640920000000003,-0.025659179,-0.006395678,-0.028906711,-0.28073449300000003,-0.03393756,0.015744025,-0.008415841,0.020523053,-0.024449989,-0.026868367999999997,-0.023958208999999998,0.011166853000000001,-0.075901186,0.018087765,-0.25048784,-0.310981145,1.666082389,2.228923006,-3.718199545,-5.158211548,-2.37640081,-3.374036812,-4.417221596,-3.2651269610000004,-4.45301294,-0.047543185999999994,-8.275785446166992,-8.449254989624023,-3.9747841358184814,-2.4444079399108887,-6.989602565765381 -2649,2649,W163M,-0.027461381,0.014279646000000002,0.015744117,0.028577104,-0.069283073,-0.049284425,-0.040138928,-0.014783833,0.02579427,0.045938560999999996,-0.017379269,0.022970251,0.008517983,0.03119251,0.025961698,-0.051278382000000004,-0.087287764,1.201765173,2.357535951,-4.51601823,-5.9294625320000005,-3.4723018039999998,-3.2711240619999997,-5.766464394,-4.140738358,-4.753816644,-1.972144633,-4.971271514892578,-7.29302453994751,-3.610011339187622,-2.1566238403320312,-4.8473687171936035 -2650,2650,W163L,-0.005738165999999999,-0.017272036,-0.010926389,-0.019421487,-0.240498541,-0.065915422,-0.00222784,-0.009248491,0.026852222999999998,-0.031701649,-0.0028424229999999997,-0.023952077999999998,0.002099301,-0.03093215,-0.007910824,-0.219883572,-0.26111350899999997,1.298661257,1.9812062380000002,-4.041255077,-5.426585693,-2.683202675,-3.3566309889999997,-5.819443794,-2.9204122310000002,-4.422816616,-0.963830443,-5.171957015991211,-6.600742816925049,-2.518160820007324,-0.8003309965133667,-5.305780410766602 -2651,2651,W163N,-0.035596295,-0.000848432,-0.01498105,-4.1e-05,-0.20943181100000002,-0.096141014,-0.044082484000000005,-0.027110105,0.028833241000000003,0.0030068390000000003,-0.004703702,-0.008604131,-0.021357967999999998,-0.011583825,0.011501892,-0.196830007,-0.222033614,1.3661810580000002,2.096238498,-2.741142307,-3.919673538,-1.696096794,-2.140633743,-3.26898317,-2.680324287,-3.751011301,-0.622034493,-4.2297468185424805,-6.143215179443359,-3.7338998317718506,-1.6969197988510132,-5.478775978088379 -2652,2652,W163Q,0.028755978999999997,0.013221041000000001,0.018205583,0.003915841,-0.35566712799999994,-0.075654338,0.04726543,0.010246527,0.039989952,0.031741962,-0.00529988,0.004613625,0.03179754,-0.02537953,0.033211211000000004,-0.27853461399999996,-0.432799641,1.5592541469999999,2.155940437,-4.636570882,-5.0557308039999995,-3.836182777,-5.228609634,-4.728254456,-4.334076736,-4.643901428,-2.981449477,-8.26683235168457,-6.712587833404541,-4.13645601272583,-3.443545341491699,-7.784145832061768 -2653,2653,W163P,0.009120472,-0.02635468,-0.004832039000000001,-0.013349479,-0.605318946,-0.0579525,0.0075217209999999994,0.010719221999999999,0.027258865,-0.027033165,-0.025676194,-0.038973999,0.029309921,-0.042592812,0.015893855,-0.487806109,-0.722831782,1.311143135,1.726085232,-4.895965512,-6.14794355,-3.84308828,-4.648128693,-5.622339408999999,-4.218327629,-4.79332921,-1.261463893,-8.839448928833008,-10.025339126586914,-4.383663177490234,-5.993285655975342,-8.372546195983887 -2654,2654,W163S,0.036677386,-0.0016396479999999998,0.007884911,-0.0034788370000000002,-0.340141466,-0.048247998,0.048088381,0.02526639,-0.006405619,-0.004025397,0.0007461010000000001,0.0063504419999999995,0.00941938,-0.037140276,0.030182602000000003,-0.28406860899999997,-0.396214322,1.7996795230000002,2.299866525,-5.467296619,-6.285222678999999,-3.731226402,-5.012857521,-6.345606651000001,-5.961569839,-5.502603165,-1.431180778,-7.3525166511535645,-6.558258533477783,-3.1692705154418945,-3.652717113494873,-6.45538854598999 -2655,2655,W163R,0.0054144219999999995,0.005021383,0.01892314,0.0039578090000000005,-0.27588543600000004,-0.043200888,-0.003029639,0.013858483000000001,0.022698394,-0.009082549,0.019125315,0.020917291,0.016928989,-0.005311059,0.013226676000000001,-0.235232763,-0.316538108,1.589341757,2.2147864680000002,-2.203317815,-3.0597011110000003,-1.305087616,-1.9336207280000002,-3.046082634,-1.672096985,-3.799333137,-0.455727836,-7.863347053527832,-5.947048664093018,-2.9192559719085693,-2.277198314666748,-6.573734283447266 -2656,2656,W163T,0.026030697999999998,-0.00950633,0.018414281,-0.008092335,-0.19232654899999999,-0.042025362999999996,0.040276062,0.011785334,0.044459107000000005,-0.018191881,-0.0008207789999999999,0.015689248,0.021139314,-0.037361264,0.021176595,-0.163657854,-0.22099524399999998,1.3999701709999999,2.161120397,-2.860510988,-3.299626335,-1.190045647,-2.176510834,-4.291277802,-3.345094322,-3.367915352,0.035773602,-5.806475639343262,-6.219951629638672,-2.1438188552856445,-1.2178062200546265,-3.6164674758911133 -2657,2657,W163V,-0.012845111000000001,0.003346084,-0.03357242,-0.022842559,-0.158162042,-0.033819977,-0.013786516,-0.011903705,0.028684072,-0.006799105,0.013491272,-0.024645418,-0.042499420999999996,-0.031542957,-0.014142161,-0.140497361,-0.17582672300000002,1.487756609,2.299630945,-4.437708655,-5.883965003999999,-3.386404114,-3.747049347,-5.040678932,-4.130445877,-4.502405871000001,-1.985671467,-5.658180236816406,-6.181082248687744,-2.327540159225464,-2.466540813446045,-6.3965044021606445 -2658,2658,W163Y,0.02722189,-0.0030464940000000003,0.01867395,0.005171987,-0.110791918,-0.08993173199999999,0.042378158,0.012065621,0.033166042,0.01120954,-0.017302528,0.019897462,0.017450438000000002,0.025115977999999997,-0.014772005,-0.067840142,-0.15374369300000001,1.233653721,2.383984478,-2.830430898,-3.969158829,-2.220497475,-2.699337395,-2.323745209,-2.9394155810000004,-3.3874585919999998,-0.467958473,-6.03737735748291,-5.305245399475098,-1.3389818668365479,-2.370377540588379,-4.566066741943359 -2659,2659,E164A,0.060081527999999995,-1.612476742,-2.264349123,-2.192751981,-3.2218152160000004,-0.043044177,0.06828318400000001,0.051879872,-0.086693326,-1.669124241,-1.555829242,-2.347685213,-2.181013032,-2.155222551,-2.23028141,-3.0907137380000003,-3.3529166939999997,-0.163810327,-1.077986141,-9.986277783,-9.777449875,-14.84284362,-9.440222473,-8.978788147000001,-6.892084801,-6.736497347999999,-4.056130563,-10.71946907043457,-12.224541664123535,-9.748831748962402,-14.548372268676758,-14.840250015258789 -2660,2660,E164C,0.042852698,-1.8898592,-2.475895522,-2.272275165,-3.04428599,-0.12652358,0.06673181,0.018973586,-0.075213509,-1.937131955,-1.842586445,-1.97887083,-2.972920213,-2.154384953,-2.3901653769999998,-2.7218993539999996,-3.366672626,-0.420073284,-1.137605922,-14.83487093,-15.15025117,-19.821886399999997,-13.92187298,-14.22212894,-11.05821514,-9.509415575,-5.173556779,-14.708030700683594,-17.855274200439453,-11.874561309814453,-17.252241134643555,-18.452075958251953 -2661,2661,E164D,-0.007808159,-0.862277112,-1.4364562969999999,-1.866212101,-2.074786308,0.140039246,0.064298429,-0.07991474700000001,0.012151186000000001,-0.873595235,-0.8509589879999999,-1.408249632,-1.464662961,-1.935946273,-1.7964779290000001,-1.929429406,-2.220143209,4.265619212,2.51794917,-9.415001616,-9.728662399,-12.64203629,-7.78894162,-8.804949509,-8.110418266,-7.339123221,-3.612970264,-10.926712036132812,-12.488388061523438,-9.60169792175293,-10.599061965942383,-13.048849105834961 -2662,2662,E164G,-0.01671895,-1.4969065769999998,-2.046241694,-2.318558303,-3.05785632,0.21739662899999998,0.018817143,-0.052255042,-0.13929654800000002,-1.588389565,-1.405423589,-2.001965646,-2.0905177409999998,-2.142717663,-2.494398943,-2.670360552,-3.445352087,0.644588947,-0.9257344470000001,-13.25631682,-12.53022195,-14.93158228,-14.52949016,-12.15780497,-12.13248476,-7.68726208,-4.303261268,-11.48344612121582,-13.459410667419434,-11.557013511657715,-14.514042854309082,-15.354326248168945 -2663,2663,E164F,0.047813307,-1.671370539,-2.0734184680000003,-2.553786504,-2.825797328,0.671854585,0.10723386300000001,-0.01160725,-0.19334970199999998,-1.586414176,-1.7563269019999999,-2.4063043,-1.740532635,-2.104697169,-3.002875838,-2.371181574,-3.280413082,0.049409217000000005,-1.09447395,-14.74076965,-16.14969238,-21.10988087,-13.03793656,-12.92461571,-10.48172276,-7.301922069,-3.3752715139999996,-14.455065727233887,-17.62405776977539,-12.723657608032227,-16.598846435546875,-18.777355194091797 -2664,2664,E164I,0.045687699000000005,-1.75360409,-2.3880954180000002,-2.6844750619999997,-2.868440257,-0.028313282999999998,0.063659295,0.027716102000000003,-0.09656561699999999,-1.9682673640000001,-1.538940816,-2.010006239,-2.766184597,-2.486550358,-2.882399765,-2.576943504,-3.1599370089999996,-0.951815022,-1.149341479,-16.12982331,-16.01400848,-23.66417783,-14.72477146,-14.92762304,-11.31853572,-7.202635244,-2.84127593,-12.832393646240234,-14.934858322143555,-9.82280445098877,-13.090363502502441,-17.74908447265625 -2665,2665,E164H,-0.017968573,-1.4953735819999998,-2.037760335,-2.8993068639999997,-3.233787056,0.319599769,0.028954011,-0.06489115599999999,-0.071897395,-1.60822971,-1.3825174530000002,-2.17284733,-1.90267334,-2.524452713,-3.2741610139999997,-2.915875854,-3.551698258,-0.171126709,-1.027088092,-12.99250601,-13.59337513,-18.60009975,-10.53248678,-13.81210065,-8.424467766,-7.643004972000001,-5.665809293,-13.842764854431152,-16.398609161376953,-12.999187469482422,-16.557275772094727,-17.18301010131836 -2666,2666,E164K,0.07764884799999999,-0.9649074609999999,-1.8048512819999998,-2.709972898,-2.893938093,0.261358198,0.136223798,0.019073897,-0.052096634,-1.192838972,-0.73697595,-1.933547851,-1.676154713,-2.586183229,-2.8337625660000003,-2.676576375,-3.11129981,0.637961867,-0.692884232,-12.12417852,-14.08195161,-15.0365836,-11.27590714,-10.23982819,-9.986622047000001,-7.924268873,-4.6712608289999995,-12.726046562194824,-12.496061325073242,-11.182869911193848,-13.085046768188477,-14.275976181030273 -2667,2667,E164M,-0.07061345299999999,-1.76490504,-2.454504108,-2.8389293810000003,-2.8723795780000003,-0.05941116,-0.061668968,-0.079557937,-0.148565211,-2.0765004069999997,-1.4533096719999998,-2.4192692780000002,-2.489738937,-2.594783401,-3.08307536,-2.3841465509999997,-3.360612604,-0.523940497,-1.198749995,-16.28372884,-16.37340189,-23.49623007,-17.28861965,-13.46835154,-10.79204105,-7.841701523999999,-1.6495750530000002,-12.387361526489258,-15.416971206665039,-9.636711120605469,-13.83598518371582,-17.558250427246094 -2668,2668,E164L,0.033686007000000004,-1.6406609369999998,-2.084481891,-2.199711708,-3.3575570939999997,-0.07898183,0.076089691,-0.008717677,-0.109367785,-1.7220767780000001,-1.559245095,-2.219747608,-1.949216174,-2.094231735,-2.305191681,-2.8536316619999997,-3.861482526,-0.0738483,-1.077391623,-16.5373069,-15.47368821,-25.50088382,-16.15609193,-15.90736565,-9.648504875,-7.76554407,-1.825243809,-12.651285171508789,-14.950310707092285,-10.317567825317383,-14.328878402709961,-16.401731491088867 -2669,2669,E164N,0.070888483,-1.519066213,-2.054373714,-2.549723362,-2.321734186,-0.015868095,0.100831856,0.040945109,-0.183928833,-1.843146495,-1.19498593,-1.583855374,-2.5248920530000003,-1.981218247,-3.118228476,-2.247702652,-2.39576572,-0.19680047399999998,-1.097205403,-13.77679116,-13.08011882,-20.64650765,-11.46499214,-13.78201531,-9.910321892,-8.374249392000001,-5.6974776,-14.234649658203125,-16.114967346191406,-11.002294540405273,-12.905592918395996,-16.599279403686523 -2670,2670,E164Q,-0.023614264,-1.5791390419999998,-2.607478655,-2.753343301,-2.9373084960000004,0.081904883,0.008414102,-0.055642629000000006,-0.171909002,-1.7038863469999999,-1.454391737,-2.347685213,-2.867272096,-2.523199337,-2.983487264,-2.613592483,-3.261024508,0.028323947999999998,-1.114274362,-10.36497338,-10.38402042,-14.54017455,-10.09036394,-8.302261192000001,-8.508046783,-8.209619257,-4.6209597769999995,-10.713912010192871,-11.744863510131836,-9.316751480102539,-13.930107116699219,-13.318994522094727 -2671,2671,E164P,0.013400888,-1.594031721,-2.05750879,-2.298539285,-3.133019478,0.779437498,0.013449474,0.013352301,-0.135692506,-1.65230214,-1.5357613019999998,-2.244948484,-1.870069096,-2.374705116,-2.2223734530000003,-3.1640682669999998,-3.101970688,0.129210937,-1.063470648,-13.99691298,-13.26590295,-20.714085,-13.18403093,-11.41228649,-11.40825954,-7.080408718999999,-3.991932528,-14.432693481445312,-15.523996353149414,-10.43337631225586,-17.63227081298828,-18.981794357299805 -2672,2672,E164S,0.07998695,-1.51626711,-2.03562332,-2.570563591,-3.0186656739999997,-0.029009699,0.089032031,0.070941869,-0.127538086,-1.556707249,-1.47582697,-2.162717554,-1.908529085,-2.162140418,-2.978986763,-2.604716082,-3.4326152660000004,0.160209508,-1.008871423,-11.28197355,-11.86368515,-14.71403962,-10.76322996,-10.61644279,-8.452470222,-7.489372744,-4.554672735,-11.623517036437988,-15.082483291625977,-9.879149436950684,-15.385643005371094,-16.806636810302734 -2673,2673,E164R,0.024984801,-1.575212651,-2.063286221,-2.367241537,-3.21360509,0.25047407,0.061539736,-0.011570134,-0.048808402,-1.6690907680000002,-1.4813345340000001,-2.108769651,-2.01780279,-2.1703404230000003,-2.56414265,-2.77261693,-3.65459325,-0.23383806399999998,-1.06432715,-12.85866729,-16.97799489,-17.48598087,-11.89997205,-10.89856807,-7.030820541000001,-7.504945356,-3.74604217,-14.121694564819336,-15.843052864074707,-12.59092903137207,-16.21530532836914,-17.264202117919922 -2674,2674,E164T,0.010001866,-1.610440827,-1.859895778,-2.660752843,-2.9327636669999997,-0.001658881,0.025253742000000003,-0.00525001,-0.100629596,-1.6954367719999999,-1.525444882,-1.9712588519999998,-1.7485327030000002,-2.389811025,-2.9316946610000003,-2.7812341660000004,-3.0842931680000003,-0.146316878,-1.083531939,-12.77417935,-12.48618042,-16.62658763,-12.8216103,-12.288056800000001,-9.648461594,-7.364157477999999,-2.591350626,-11.652033805847168,-14.323148727416992,-7.176640033721924,-13.66916275024414,-16.17547035217285 -2675,2675,E164W,0.019793274,-1.743472752,-1.94107118,-2.089505645,-3.386125481,0.38113443,0.05830954,-0.018722993,-0.12484927800000001,-1.7306580669999998,-1.756287437,-2.1148196230000003,-1.767322736,-2.086213763,-2.092797526,-3.079696896,-3.692554065,-0.07923592900000001,-1.096493081,-16.60174596,-16.59210052,-24.01899975,-14.635981099999999,-15.18935376,-12.57229465,-9.281906954,-6.9072445039999995,-14.497544288635254,-19.141082763671875,-13.896892547607422,-17.845930099487305,-18.86510467529297 -2676,2676,E164V,-0.000619346,-1.63607516,-2.370896214,-2.6778705069999997,-2.972760077,0.027243369,0.032563102999999996,-0.033801793999999996,-0.093644343,-1.751847366,-1.5203029540000002,-2.3164649859999997,-2.425327441,-2.668070369,-2.687670645,-2.758463515,-3.187056638,-0.320547108,-1.0962405000000002,-15.05635287,-15.98477374,-22.33514816,-15.28839175,-13.15785397,-8.515596741,-7.401599207,-2.541422135,-11.173985481262207,-13.00638198852539,-8.690889358520508,-14.26060962677002,-16.347881317138672 -2677,2677,E164Y,0.03419084,0.02249866,-0.250997542,-2.16514141,-2.8886972280000003,0.38077883,0.044170005,0.024211675,-0.08053550799999999,-0.018462261,0.06345958,-0.401525726,-0.10046935800000001,-1.957251092,-2.373031728,-2.348674233,-3.428720222,1.509662845,0.727258264,-13.05504209,-12.47342389,-15.85017612,-12.24386271,-13.67717688,-11.03057085,-7.910881037999999,-4.914496409,-13.601356506347656,-18.33609962463379,-12.769773483276367,-16.552505493164062,-17.205581665039062 -2678,2678,P165A,-0.016733368000000002,0.007880625,-0.034554958,-0.043266222,-1.173297695,0.034138603999999996,0.009538584000000001,-0.04300532,-0.062866577,0.002791609,0.01296964,-0.043286331,-0.025823584,-0.04922396,-0.037308483999999996,-1.074569156,-1.2720262340000001,0.7889830640000001,1.360357597,-5.439867134,-5.34206955,-6.32000222,-4.779540894,-5.812777702000001,-4.944945305,-6.015881912,-1.997706994,-6.150207996368408,-8.137618064880371,-7.984613418579102,-8.116024017333984,-7.124747276306152 -2679,2679,P165C,-0.027506983999999998,-0.005332266,0.005881785,-0.018828128,-1.21695688,0.11934187800000001,-0.015400974,-0.039612993,-0.049711029000000004,-0.020762888,0.010098356,-0.031627853,0.043391423,-0.04121098,0.0035547240000000004,-0.9955328109999999,-1.4383809490000001,0.877315521,1.38499411,-10.35793833,-10.29139707,-10.846954199999999,-9.935764282000001,-10.25413562,-10.46144045,-8.575837471,-6.433138002000001,-8.599645614624023,-12.897736549377441,-10.787307739257812,-11.305488586425781,-11.387971878051758 -2680,2680,P165E,-0.050869929,-0.068533198,-0.034488838,-0.013063191000000002,-1.695484262,0.06243829099999999,-0.049110449,-0.052629407999999996,-0.152343413,-0.014385442,-0.12268095400000001,-0.045382689000000004,-0.023594987,-0.022493079,-0.003633303,-1.599415826,-1.791552697,0.592780347,1.309902125,-6.655948991,-5.554859108,-6.3817614979999995,-6.417485451,-8.71442318,-6.211215721,-6.028212777999999,-1.389311094,-8.268796920776367,-12.338981628417969,-11.623600006103516,-10.93382740020752,-11.8954496383667 -2681,2681,P165D,-0.025071542999999998,0.002011079,0.045051231,-0.013742967,-1.556104221,0.096454195,-0.048090737,-0.0020523489999999998,-0.043322188,0.044492372999999995,-0.040470215,0.065763029,0.024339432,-0.010674099,-0.016811835,-1.430204906,-1.682003535,0.81676416,1.333682387,-8.603315869,-7.89198024,-9.719175156,-7.822255408999999,-9.803118416,-7.780050125,-6.842423371000001,-2.484471346,-8.57640266418457,-14.148540496826172,-11.64600658416748,-10.906073570251465,-12.95254135131836 -2682,2682,P165G,-0.00819141,-6.22e-05,0.020981296,-0.017634149,-1.984731056,0.5119298870000001,-0.014370118999999999,-0.0020127,-0.024571737000000003,-0.010564631000000001,0.010440258000000001,0.013827533999999999,0.028135057,-0.019376455,-0.015891843,-1.612710189,-2.356751922,0.8211996640000001,1.323318012,-6.557051443,-5.797379967,-7.371419158999999,-5.583146393,-7.423402077,-6.609909622000001,-4.3890053810000005,-2.33455074,-8.37905502319336,-12.138641357421875,-10.556013107299805,-11.168420791625977,-11.973176956176758 -2683,2683,P165F,-0.01085904,0.019954104,-0.015868725,-0.406435173,-2.2579569999999998,0.010724588,0.00905794,-0.030776018999999998,0.002236849,0.035793591,0.004114617,-0.012309196000000001,-0.019428253,-0.334958944,-0.477911401,-2.1271868659999997,-2.388727133,1.423129076,1.3201015520000001,-10.49646352,-11.37263591,-11.40585867,-10.29292464,-9.39954377,-10.01135462,-7.016608565,-3.723470471,-9.121649742126465,-13.229394912719727,-10.045459747314453,-10.918179512023926,-11.675304412841797 -2684,2684,P165I,-0.08305615400000001,-0.097487041,-0.06583080599999999,-0.026895758999999998,-0.527164155,0.087868882,-0.065145226,-0.100967081,-0.121657413,-0.101440838,-0.093533243,-0.055150990999999996,-0.076510621,-0.077780985,0.023989467,-0.48736758,-0.5669607289999999,1.4833693980000002,1.833297393,-5.878281656,-7.265974655,-5.241792908,-5.763110427999999,-5.142780548,-5.977749741,-5.399850107000001,-3.383961555,-6.5844407081604,-7.792078971862793,-9.542526245117188,-8.039068222045898,-7.052148818969727 -2685,2685,P165H,-0.028253211,0.074433425,0.037302612,-0.0033447729999999997,-1.577464349,0.06861828,-0.027767151,-0.028739271,-0.085304331,0.10366511,0.045201739000000005,0.063479522,0.011125702,0.037103376,-0.043792921,-1.687485874,-1.467442823,0.550480827,1.311128903,-11.30406255,-10.45648767,-12.17027256,-10.72555392,-11.82903829,-11.33896029,-6.4196512939999995,-4.209086751,-8.045969009399414,-11.446649551391602,-10.668484687805176,-11.085456848144531,-11.492451667785645 -2686,2686,P165K,-0.077917685,0.01561813,0.048688664000000006,-0.023009987000000003,-1.4789790369999998,0.087393433,-0.080474196,-0.075361173,-0.04686832900000001,0.04081352,-0.009577261,0.06943408,0.027943247999999997,-0.057194842,0.011174868999999999,-1.287357979,-1.670600095,0.8722444140000001,1.35109225,-7.859878687999999,-7.521869095,-8.293712059,-7.52424176,-8.017999496,-7.94157103,-6.183537599999999,-2.8385696210000004,-7.2967658042907715,-12.147415161132812,-11.418113708496094,-10.63766098022461,-11.162247657775879 -2687,2687,P165M,-0.06203848,0.032466781,-0.016022998,-0.01479749,-1.40629147,0.064640505,-0.056152818,-0.067924141,-0.017893304,0.09360106300000001,-0.028667501,0.027576097999999997,-0.059622093,-0.005336723000000001,-0.024258257000000002,-0.926049954,-1.886532986,0.7054294320000001,1.362729995,-7.033396741000001,-8.282557938,-7.707186432,-6.9164458689999995,-6.0927047729999995,-6.168088692,-5.743922281000001,-1.23292792,-7.063819885253906,-9.745821952819824,-10.28723430633545,-9.15117073059082,-8.577790260314941 -2688,2688,P165L,-0.052139845,-0.030492476,-0.004881636,-0.0492441,-0.353187675,0.077862419,-0.030475515,-0.073804174,-0.037516667999999996,-0.017925639,-0.043059312,-0.011190511,0.00142724,-0.069927285,-0.028560914,-0.330801969,-0.37557338,1.639272118,2.1064305269999997,-5.303714005,-5.911280426,-5.80230069,-5.918609107999999,-3.99254702,-4.893832778999999,-4.59204158,-2.6580992119999998,-5.80908203125,-9.421346664428711,-8.812809944152832,-8.309871673583984,-6.963190078735352 -2689,2689,P165N,-0.101002375,-0.047014558,-0.050951410999999995,-0.029849685,-0.771029889,0.12393356900000001,-0.083691858,-0.11831289099999999,-0.093427861,0.002174404,-0.096203519,0.000890953,-0.102793775,-0.014487238000000001,-0.045212132,-0.6962331829999999,-0.845826595,0.8988129020000001,1.44151548,-9.085535353,-8.259350449,-8.807022636000001,-9.00291597,-10.35720254,-9.001185173,-6.809225285,-4.081631892,-7.326167106628418,-11.834412574768066,-10.36977481842041,-10.028776168823242,-10.948437690734863 -2690,2690,P165Q,-0.049024242,-0.032043953,-0.016391273999999997,-0.035589283,-1.4011301680000001,0.11882595300000001,-0.026089453,-0.07195903,0.01105237,-0.05505103099999999,-0.009036875,-0.04377054,0.010987992,-0.08856547699999999,0.017386911,-1.400062259,-1.402198076,0.8778117940000001,1.34188831,-7.5853816510000005,-6.856364731,-7.2980574339999995,-7.996603378,-8.200913101,-7.574969612,-5.935129142,-3.2067370110000004,-7.414444446563721,-8.872124671936035,-10.404653549194336,-10.161785125732422,-10.423163414001465 -2691,2691,P165S,-0.025469442999999998,-0.001371008,-0.014335531,-0.022500626,-1.27638993,0.096454717,-0.015835167,-0.035103719,-0.07283745400000001,0.007983579000000001,-0.010725595,-0.025443989,-0.003227073,-0.028796255,-0.016204997,-1.052852307,-1.499927553,0.734930165,1.355711725,-6.075066382999999,-5.829662537000001,-6.144133148,-5.5774188229999995,-6.951619292999999,-5.872498116,-5.761526514,-3.420295173,-5.555652618408203,-8.315799713134766,-7.723125457763672,-7.9993896484375,-8.130083084106445 -2692,2692,P165R,-0.048184529000000004,-0.001356164,-0.031512507,-0.02700193,-1.540979088,0.093436315,-0.034464369,-0.061904688,-0.075911142,-0.005726846999999999,0.0030145190000000002,-0.036748525,-0.026276489,-0.033197566,-0.020806294,-1.490084126,-1.59187405,0.87453776,1.3360578920000001,-8.215258452,-8.510146393,-6.630752304,-8.631724472,-8.76505162,-8.53861747,-6.050950092000001,-1.666131033,-6.790772438049316,-11.588033676147461,-10.617050170898438,-10.036476135253906,-10.979244232177734 -2693,2693,P165T,0.005106602,-0.011358968999999998,0.011091829,-0.052929989000000004,-0.07192525,0.18885133699999998,0.001738694,0.008474509,0.015913881,-0.039608596,0.016890659,-0.011741702,0.03392536,-0.069964177,-0.035895800000000005,-0.067439057,-0.076411442,1.3394774040000001,2.3829762480000003,-0.7391094559999999,-1.4596145630000001,-0.833903107,-0.039168251,-0.6712362140000001,-0.691625145,-0.48366884299999996,-1.124361004,-1.1411356925964355,-4.597027778625488,-3.9303712844848633,-4.403515815734863,-2.884427070617676 -2694,2694,P165W,-0.060405824000000004,-0.035290598,0.0007291089999999999,-1.033370532,-2.673980819,0.10259163,-0.038408606,-0.082403041,-0.052964187,-0.037211011,-0.033370184,0.018639026,-0.017180808,-0.90585557,-1.1608854929999999,-2.25562861,-3.092333027,1.944259419,1.355310934,-11.332984800000002,-11.51044146,-11.86488109,-11.13626993,-10.78120815,-11.37212335,-7.9845478320000005,-5.758762842,-10.736099243164062,-15.837409019470215,-13.150213241577148,-12.913068771362305,-14.718751907348633 -2695,2695,P165V,0.035725667,-0.016343426,0.021251806,-0.005679023,-0.337033628,0.12288474699999999,0.039732766,0.031718567,-0.032393622999999996,-0.031516981,-0.00116987,-0.004236597,0.046740208,-0.057212106,0.045854060999999995,-0.328455505,-0.34561175,1.3882191680000002,1.906566134,-5.286228102,-6.600841461,-4.5662672419999994,-5.57330162,-4.637094635,-5.053635551,-4.763265908999999,-3.452250285,-4.7652788162231445,-8.351933479309082,-9.006688117980957,-8.26569938659668,-6.006089210510254 -2696,2696,P165Y,-0.05969833,-0.010500713,-0.021927772,-0.2657837,-2.125045058,0.059893315999999995,-0.084765516,-0.034631143999999996,-0.021487485,0.001063511,-0.022064936,-0.038038031,-0.005817513000000001,-0.174348417,-0.357218983,-1.83168232,-2.418407796,1.182857733,1.336381752,-11.43221446,-11.899652900000001,-12.47692651,-10.72964124,-10.12848338,-11.92636829,-6.538755134,-4.065942387,-9.712480545043945,-14.426895141601562,-11.525030136108398,-11.52186393737793,-12.670607566833496 -2697,2697,E166A,0.028897534,0.053025132999999995,0.027068808,0.015776523,-0.011919645,-0.039928032,0.022350953,0.035444115,0.01660418,0.058270712999999995,0.047779552999999995,0.025041817,0.029095798,0.020240908999999998,0.011312137,-0.010822328999999999,-0.013016961,1.200270332,2.547443944,-1.2554742,-1.019653687,-1.175729828,-1.3899512019999998,-2.28187011,-0.410166176,-1.7526302619999998,-1.177230575,-5.503973007202148,-6.154193878173828,-5.816701889038086,-6.146048545837402,-7.399346828460693 -2698,2698,E166C,-0.045742172000000005,0.015361678,0.00329139,-0.017483942,-0.058989229000000004,0.042248658,-0.062503449,-0.028980894,0.008122436,0.058928220999999996,-0.028204865,0.04375141,-0.03716863,0.000474356,-0.035442239,-0.02716621,-0.09081224800000001,1.266356399,2.540481288,-7.867562567,-8.238912063999999,-6.461035461,-8.170910088,-8.914844414,-7.552110809,-9.087975262999999,-9.120583477,-11.621987342834473,-13.60924243927002,-11.61503791809082,-11.723864555358887,-14.057218551635742 -2699,2699,E166D,0.050109756,0.053185069,0.025114711,0.03902202,0.0055922459999999995,0.010924678,0.033129529,0.067089982,0.048700720999999995,0.049754575,0.056615563,0.003071688,0.04715773400000001,0.061157715,0.016886325,-0.023748325,0.034932817000000005,1.247305402,2.690587958,-1.558416658,-1.6140271990000001,-1.0665284879999999,-2.273651215,-1.899801384,-0.938075005,-2.6296255719999997,0.104510265,-5.5489349365234375,-5.557431221008301,-4.337039947509766,-5.41618013381958,-6.798323631286621 -2700,2700,E166G,-0.000124314,0.048933150999999994,0.010628576,0.012021878,-0.060012719000000006,0.02457081,-0.009734024,0.009485396,0.030882696,0.073761315,0.024104987,0.031874634,-0.010617482,0.055789270999999994,-0.031745515,-0.045158023,-0.07486741400000001,1.359022036,2.750051038,-3.504978767,-3.954187805,-2.612458504,-3.9655043869999997,-4.609133415,-2.383609726,-4.198108028,-1.85002317,-7.223153114318848,-9.22784423828125,-7.194223403930664,-7.650726318359375,-8.598325729370117 -2701,2701,E166F,-0.030926282000000003,-0.006136848,-0.057421625999999996,-0.012560358,-0.047233269,0.0044261909999999995,-0.023937201,-0.037915363,0.057084392000000005,0.047670141,-0.05994383599999999,-0.048494753,-0.06634849799999999,0.009541683,-0.034662398,-0.021271756,-0.073194781,1.313536315,2.5357030959999998,-5.32225546,-6.378616882,-3.845511887,-5.8559558329999994,-5.809816452000001,-4.721376244,-5.408989424,-4.146250001,-10.40983772277832,-10.799975395202637,-10.422778129577637,-9.329978942871094,-11.827942848205566 -2702,2702,E166I,0.06821282099999999,0.009041805,0.07331724099999999,-0.021082512,-0.12248105699999999,0.017751235,0.062237392,0.074188249,0.099266386,0.012979629,0.00510398,0.062207407,0.084427074,-0.007386076,-0.034778948,-0.141486936,-0.10347517699999999,1.4258734830000002,2.2779851840000003,-6.743083907999999,-7.1448594210000005,-4.6763070980000006,-6.842818619,-7.413378426,-7.6380559770000005,-5.867705282999999,-3.635250767,-8.048760414123535,-11.076333045959473,-10.412436485290527,-9.164949417114258,-10.910146713256836 -2703,2703,E166H,0.064472407,0.051440066,0.040566516000000004,0.027583492,0.05818229900000001,0.039333807,0.05801755,0.070927263,0.018967839,0.091067262,0.01181287,0.057981532,0.0231515,0.058973315,-0.0038063309999999996,0.05307161,0.063292988,0.982773914,2.721089062,-4.3961254069999995,-3.478350189,-2.777450661,-5.111515839,-5.914437775,-4.698872574,-5.08801418,-3.227800228,-9.255758285522461,-9.70235538482666,-8.512484550476074,-8.108845710754395,-8.738165855407715 -2704,2704,E166K,0.020863923,0.020961004,0.014419564,0.02774677,-0.058571476,0.03636585,0.028522177000000003,0.013205668,0.046108764,0.029813107999999998,0.0121089,0.015182768999999999,0.013656359,0.036830009,0.01866353,-0.037009349,-0.080133602,1.226266326,2.521170292,-4.167360892,-5.2637084960000005,-2.7437820360000003,-4.016729233,-4.565670715,-4.2469139789999995,-4.75153837,-2.923080742,-7.610034942626953,-9.83322811126709,-7.774946212768555,-8.322073936462402,-8.937474250793457 -2705,2705,E166M,-0.035666653,0.036783627,0.049154719000000006,0.010634656999999999,0.0037124809999999997,0.016741465,-0.059572027,-0.011761278,0.026132807999999997,0.10371128,-0.030144027,0.078167087,0.020142351,0.033558524,-0.012289211000000001,0.040133707000000005,-0.032708745,1.1101980409999999,2.8497304039999998,-5.1117846280000006,-5.185610504,-3.5983088530000003,-5.524823242,-6.152654838999999,-5.0975257030000005,-5.347416013,-3.727191659,-8.287576675415039,-9.921379089355469,-9.53153133392334,-7.313227653503418,-10.713959693908691 -2706,2706,E166L,0.01323957,0.038615914,0.014330124,-0.003781048,-0.040056983,-0.049241371,0.007776205,0.018702933999999997,0.022666707,0.06609844,0.011133388000000001,0.016738469,0.011921778999999999,0.015639879,-0.023201974,-0.040721501,-0.039392464,1.217689593,2.419237274,-4.712764226,-4.465135078,-2.748326004,-4.867181625,-6.12572052,-5.357457901,-4.345703609,-2.8497774319999998,-7.2848358154296875,-9.221628189086914,-9.577838897705078,-8.16327953338623,-9.69954776763916 -2707,2707,E166N,-0.042662335999999995,0.015499862,-0.005370071,-0.004348513,-0.069317183,0.012366294,-0.035269206000000004,-0.050055465,-0.0031013,0.05670018,-0.025700456,0.077285521,-0.088025663,0.069957832,-0.078654858,-0.020284215,-0.11835015,1.16455779,2.53594446,-4.928578003999999,-5.743958999999999,-3.646906555,-5.044894783,-5.570473991,-4.636655693,-5.389385582,-3.809826025,-8.327324867248535,-8.861358642578125,-7.47521448135376,-7.810297012329102,-8.928352355957031 -2708,2708,E166Q,-0.015855998,0.026265542000000003,-0.016725943,-0.007830972,-0.021115558,-0.022885249,-0.037881654,0.006169659,0.045396228,0.04722965,0.005301433,-0.010249882,-0.023202004,0.003709939,-0.019371882,-0.034116221,-0.008114895,1.326265902,2.462686796,-3.3926861130000003,-3.447271423,-2.0301643830000002,-4.01893441,-3.603532982,-3.863527367,-4.681928339,-1.978431199,-6.477310657501221,-7.805316925048828,-6.365139961242676,-6.512653350830078,-7.690580368041992 -2709,2709,E166P,-0.032698756,0.01452947,-0.006200669000000001,-0.051852342999999995,-1.836023503,0.032343397,-0.04542116,-0.019976352,0.011147289,0.045179547,-0.016120607,-0.009107444000000001,-0.003293893,-0.020813028,-0.08289165700000001,-1.672281006,-1.999766,0.62787574,1.307767011,-6.476953256,-6.499234137999999,-4.0388834760000005,-7.15712458,-8.492500786,-6.1970233,-6.848003815,-3.881706204,-8.94455337524414,-11.551820755004883,-9.7725830078125,-10.859931945800781,-10.476197242736816 -2710,2710,E166S,0.020317328,0.022279259,0.00918526,0.008188421999999999,-0.030948467,0.043227695,0.016488581000000002,0.024146074,0.00110348,0.05588664,-0.011328122,0.041843775,-0.023473256,0.031312917,-0.014936073999999999,-0.033723372,-0.028173561,1.152808179,2.4280021830000003,-2.4960743969999997,-2.228454887,-1.6417329790000001,-2.8108784260000004,-3.4663418580000003,-2.332963837,-3.0168554660000004,-2.333488209,-6.377089500427246,-7.920055866241455,-5.384139537811279,-7.87912654876709,-7.997853755950928 -2711,2711,E166R,0.008139333,0.027227097000000002,0.010429474000000001,0.008978958,-0.072704092,0.027905789,0.011953915,0.004324751,0.011267768999999999,0.059387225999999994,-0.004933033,0.019658111000000002,0.001200837,0.03211004,-0.014152125,-0.08894807800000001,-0.056460105,1.173860591,2.2452317269999997,-5.364735696,-5.849258598,-2.738401619,-6.105006691,-6.537979117999999,-5.593032455,-5.617802913999999,-2.582419616,-8.7672758102417,-10.023852348327637,-9.318633079528809,-8.825364112854004,-10.064519882202148 -2712,2712,E166T,0.012194587,0.027449286,0.01491156,-0.006641364,-0.043164957000000004,0.058641425999999996,-0.00021674599999999997,0.024605919,0.029566947000000003,0.018362755,0.036535816,0.014457191999999999,0.015365927,0.006600541,-0.019883269,-0.07259840099999999,-0.013731512,1.2045483209999999,2.313700915,-1.9546295809999998,-1.848165405,-1.540262451,-1.997500145,-2.8600383989999996,-1.5271815030000002,-3.2449866989999996,-1.762482719,-6.558239936828613,-8.32974910736084,-6.3792524337768555,-7.076570987701416,-8.369186401367188 -2713,2713,E166W,0.039062322999999996,0.044336457,0.0319567,0.034112628,-0.022417454,-0.006991553,0.025514585,0.05261006,0.061514633,0.049587385,0.039085528,0.030020903999999998,0.033892496,0.018545402,0.049679852999999996,-0.047856855,0.003021947,1.370318051,2.4874263709999997,-7.692036961,-8.595013855,-5.073739388,-8.598346634,-8.509689446,-7.683395485,-7.139362656,-4.803275952,-10.910542488098145,-12.919052124023438,-11.789295196533203,-11.253618240356445,-12.233979225158691 -2714,2714,E166V,-0.0469483,-0.018338363,-0.014486171,-0.020546363,-0.109649546,-0.003023596,-0.061429827,-0.032466773,-0.003226234,0.009109746,-0.045786472,0.017153182,-0.046125523,0.00140831,-0.042501036,-0.128059179,-0.091239913,1.272030866,2.155326384,-5.3140160860000005,-5.894460182,-3.485250671,-5.667102036,-6.490270821,-5.032996719,-5.619667403999999,-2.9776582730000003,-6.419651985168457,-9.411232948303223,-7.498748302459717,-8.166760444641113,-9.671940803527832 -2715,2715,E166Y,0.054499778,0.069139822,0.030585809,0.037582078,0.067210162,0.029815854,0.054664015,0.054335540999999994,0.028332491,0.076827045,0.061452599000000004,0.030959001,0.030212616,0.048351488,0.026812667999999998,0.02053526,0.11388506300000001,1.042526455,2.77922482,-5.070955985,-4.751033249,-4.00399115,-5.827057097999999,-5.28512278,-5.487575645,-5.062333913,-4.486062198,-10.576628684997559,-10.86153793334961,-10.336387634277344,-9.287751197814941,-10.570222854614258 -2716,2716,L167A,0.02375616,0.023421772999999996,-0.009327488,0.01719356,-0.9991797370000001,0.10636589,0.015547891999999999,0.031964427999999996,,0.0035803540000000004,0.043263191,-0.03930123,0.020646254,-0.005961933000000001,0.040349052999999996,-0.9030111959999999,-1.095348277,0.933007633,1.409695524,-8.948857176,-15.60677046,-8.645514999,-6.623279076,-8.636686043,-5.232035301,-5.87807309,-2.434138098,-12.04377269744873,-12.420669555664062,-13.70938491821289,-11.547783851623535,-14.087823867797852 -2717,2717,L167C,-0.009622641999999999,0.009378968,0.009273215999999999,0.019074902,-0.017578104,0.324937707,-0.026464725,0.0072194419999999995,,0.008120038000000001,0.010637897,0.01423978,0.004306651,0.035158349,0.002991455,0.024157897999999997,-0.059314105,1.181087765,2.7348506130000003,-12.66186066,-17.85498299,-11.60480917,-12.03028181,-11.92117337,-9.898055938999999,-9.230988578,-6.4337817479999995,-13.961485862731934,-14.394540786743164,-13.852161407470703,-12.575187683105469,-15.404864311218262 -2718,2718,L167E,-0.02351057,-0.010870129,-1.7664628,-2.019669632,-2.415411747,0.102810013,-0.0034186359999999996,-0.043602504,,0.02053398,-0.042274238,-1.768762994,-1.764162606,-1.822186766,-2.217152497,-2.547997273,-2.282826221,3.3667576280000002,1.680881465,-12.94675976,-19.18140831,-12.54914303,-10.5761946,-13.02590199,-9.401150856000001,-8.100678089,-4.33252842,-15.16478157043457,-14.714075088500977,-15.220490455627441,-13.602556228637695,-16.73700523376465 -2719,2719,L167D,-0.035346381,-0.01042663,-1.9060365119999998,-2.272300482,-3.000815722,0.129185939,-0.032638352,-0.03805441,,0.04193836,-0.062791619,-1.803261971,-2.008811052,-2.1955042999999996,-2.349096663,-2.921314807,-3.080316636,0.37461203,-0.043607626,-14.98490002,-21.245793300000003,-14.971047199999997,-12.81838144,-13.510502300000002,-12.37877585,-9.886197986,-6.827714681000001,-16.074005126953125,-15.638375282287598,-16.40584945678711,-14.73735237121582,-18.2022705078125 -2720,2720,L167G,-0.037925805,-0.00047351699999999996,-0.027186255,-1.8189604480000001,-2.5855530840000003,0.12077730800000001,-0.022551943999999997,-0.053299665999999996,,0.0036775270000000003,-0.004624561,-0.054673642,0.000301132,-1.7835424519999998,-1.854378444,-2.509352959,-2.661753208,0.7628183759999999,0.684895182,-13.31886579,-19.06172137,-13.04595895,-11.38772196,-13.09084485,-10.00808182,-7.980194748,-4.051554728,-14.919173240661621,-15.200419425964355,-15.346051216125488,-13.542146682739258,-17.664003372192383 -2721,2721,L167F,-0.063173033,-0.015112259,-0.07621069,-1.981400465,-2.1411517730000003,0.035127701000000004,-0.045568079000000004,-0.080777987,,-0.032957972,0.002733455,-0.031222862999999997,-0.12119851699999999,-1.9252089209999999,-2.037592009,-2.1281406830000003,-2.1541628630000003,0.656412805,0.665356462,-10.75441684,-13.47082108,-9.614051612999999,-10.12024406,-10.12793063,-10.4390368,-6.878747225,-2.0693424730000003,-11.780282020568848,-10.174980163574219,-11.034611701965332,-9.557394981384277,-12.149374961853027 -2722,2722,L167I,0.05100575,-0.0034796640000000004,-0.000330755,0.0074301390000000005,-0.034959372999999995,0.065152378,0.059176502,0.042834997,,-0.066577334,0.059618005999999994,-0.050664825,0.050003315,0.007061854,0.0077984230000000005,-0.022589626,-0.04732912,1.235117378,2.449877744,-7.061143477999999,-7.648991347999999,-8.380282127000001,-5.950976272999999,-7.898425507000001,-5.427042137000001,-6.633884124,-2.867073744,-8.214323043823242,-9.212763786315918,-9.30839729309082,-8.737936019897461,-8.627796173095703 -2723,2723,L167H,-0.034469499,-0.000867085,-1.054665709,-1.9923649959999998,-2.551329907,0.093240387,-0.037262444,-0.031676552999999996,,-0.045055579000000005,0.04332141,-1.223344725,-0.885986693,-2.076317892,-1.9084120999999998,-2.552250926,-2.550408888,2.409891747,0.9979500920000001,-16.64363116,-18.836947,-15.23906696,-18.80386088,-16.22647098,-14.11180997,-9.182611812000001,-5.737775406,-13.574713706970215,-12.216160774230957,-13.65045166015625,-11.751890182495117,-14.405709266662598 -2724,2724,L167K,-0.016945994,-0.43502045200000006,-2.0282116009999998,-2.2077896630000002,-3.034945182,0.109958101,-0.010870506,-0.023021481,,-0.36273882799999996,-0.507302075,-2.379603321,-1.676819881,-2.294724396,-2.120854929,-2.8955961660000002,-3.174294197,0.288556437,-0.46319435600000003,-13.62551021,-18.38776946,-13.93817324,-14.09304472,-11.41351299,-10.29505064,-8.870904918999999,-5.204226364,-15.081113815307617,-12.635360717773438,-14.11644172668457,-12.114858627319336,-14.625235557556152 -2725,2725,L167M,0.043775427,0.009471524,0.016531342,0.022821049,-0.095031072,0.212735612,0.063928759,0.023622094,,-0.01368415,0.032627197000000004,-0.039293025,0.072355708,0.013170123,0.032471975,-0.11058039199999999,-0.07948175099999999,1.50774049,2.45803467,-4.187371046,-4.031954926,-4.874016167,-4.7982671969999995,-4.337380013,-2.8952369310000003,-5.299544085,-1.444952021,-8.237210273742676,-6.488867282867432,-6.7289276123046875,-7.809287071228027,-10.395636558532715 -2726,2726,L167N,0.012186536000000001,0.004682825,-0.027263979,-0.04314168,-2.83505775,0.206138436,-0.008085061,0.032458132,,-0.012988371,0.02235402,-0.04479086,-0.009737097,-0.055704893,-0.030578467,-2.216881907,-3.453233593,0.794928913,1.283006402,-14.36409107,-20.12345877,-13.15956712,-14.22891618,-13.76821361,-10.54029967,-9.458925519,-5.911648887,-13.339147567749023,-13.416325569152832,-14.12370491027832,-11.681829452514648,-14.141040802001953 -2727,2727,L167Q,-0.025009842,0.0135106,-0.020932681,-2.180382564,-2.735504062,0.065753485,0.002580647,-0.05260033,,-0.020663875,0.047685074,-0.059283906,0.017418545,-1.7670467669999999,-2.593718361,-2.191827279,-3.279180844,0.725919014,0.683302739,-12.49625469,-19.05752506,-11.08569934,-11.49631896,-11.11901512,-9.722714981000001,-8.047710177999999,-3.448157,-12.189906120300293,-10.507857322692871,-11.86312484741211,-11.301525115966797,-14.048316955566406 -2728,2728,L167P,-0.039453729,0.035035965,-0.5308229999999999,-2.1130151319999997,-2.538317974,0.076729069,-0.024626535,-0.054280922,,0.047148925,0.022923005,-0.391859358,-0.669786641,-1.978237449,-2.247792815,-2.444410645,-2.6322253019999997,1.452976836,0.708712481,-11.83712751,-17.09582825,-11.10935645,-10.96690076,-10.89037295,-9.123179131,-7.699101584,-4.289282986,-13.117035865783691,-9.959577560424805,-13.794719696044922,-13.249201774597168,-14.542289733886719 -2729,2729,L167S,-0.014351083,0.005458001999999999,-0.016160984,-1.139683851,-2.662568311,0.076663087,-0.013320123,-0.015382042,,-0.00714593,0.018061933,-0.030257127999999998,-0.00206484,-1.401904049,-0.877463652,-2.424196924,-2.900939697,0.776848578,0.718859603,-9.927176151,-16.21591882,-8.575208069,-8.739439011,-9.445431244,-6.659883606,-6.647556096000001,-3.233205587,-13.226318359375,-11.322755813598633,-13.700546264648438,-10.079504013061523,-15.0405855178833 -2730,2730,L167R,-0.034567012,-0.871267569,-2.004142992,-2.256873182,-2.840588155,0.082187305,-0.014647651999999999,-0.054486372000000005,,-0.8370576129999999,-0.905477524,-2.1575964290000003,-1.850689555,-2.1368350030000003,-2.37691136,-2.64876569,-3.0324106189999998,1.557747297,-0.237614016,-13.93177381,-20.18027886,-13.72998726,-13.11189227,-12.67489449,-9.961816154,-8.475420964,-2.8194087000000003,-14.34022045135498,-12.099398612976074,-11.875212669372559,-12.266463279724121,-13.71399974822998 -2731,2731,L167T,0.020546643,0.025005515,-0.010561272,-0.007957307,-0.880212184,0.10991553300000001,0.027238366,0.01385492,,0.006140019,0.043871010999999994,-0.033236400000000006,0.012113856000000001,0.003372209,-0.019286823,-0.7873875290000001,-0.973036838,0.653128762,1.372324932,-11.27823165,-15.72364294,-11.45486283,-9.830364952,-11.62343649,-7.758851012999999,-8.425423517999999,-2.863191862,-11.533105850219727,-11.811240196228027,-11.674644470214844,-11.82242488861084,-13.294818878173828 -2732,2732,L167W,-0.027229514,-1.1917113320000001,-2.207127508,-2.420178964,-2.6931647460000003,0.009473129,-0.0065754459999999995,-0.047883580999999995,,-1.250436214,-1.13298645,-2.161196818,-2.253058197,-2.076317892,-2.764040035,-2.677189663,-2.709139828,2.72714215,0.27647041699999997,-14.3268215,-17.92614049,-13.04169379,-14.29523395,-13.742274300000002,-12.62876496,-9.347819131,-5.5559290610000005,-14.393174171447754,-13.627813339233398,-14.50605583190918,-13.691287994384766,-15.710630416870117 -2733,2733,L167V,-0.021767487000000002,0.013677971,-0.026588597000000002,0.015077031000000001,-0.015985525,0.077525227,-0.04327273400000001,-0.00026224,,0.00029451900000000003,0.027061422999999998,-0.012361772,-0.040815422000000004,0.025083797,0.0050702640000000005,0.002664655,-0.034635705,1.19486694,2.5247538169999997,-6.699480587999999,-7.559443459,-7.721306976,-5.325364723,-7.947934357,-4.943353424,-5.608419897,-2.8931516489999995,-9.480157852172852,-10.702177047729492,-10.769169807434082,-9.30470085144043,-9.979879379272461 -2734,2734,L167Y,-0.083214775,-1.315170882,-2.01003861,-2.575272585,-2.891833455,0.06711085,-0.055179812,-0.11124973699999999,,-1.199548166,-1.4307935980000002,-1.908204079,-2.111873141,-2.078597659,-3.07194751,-2.9013181789999996,-2.88234873,3.5937918669999998,1.297872375,-14.76272204,-15.8233928,-14.96389929,-14.276420199999999,-13.87926005,-14.87063786,-7.839318619,-3.7008447139999996,-14.32970142364502,-13.5636625289917,-13.552125930786133,-11.759808540344238,-14.868586540222168 -2735,2735,N168A,0.027702993,-0.009094956,-0.03339603,0.005673558,-1.359565393,-0.048446895999999996,0.028305074,0.027100912,,-0.004271942,-0.013917968999999999,-0.073800815,0.007008756,-0.01509123,0.026438345,-1.196243907,-1.5228868780000002,0.9145161070000001,1.366908079,-9.126523216,-7.277275826,-14.09100336,-8.593677681,-8.244965416,-7.425693794,-5.821637629,-2.081454295,-9.512711524963379,-13.440896987915039,-12.450336456298828,-13.847140312194824,-10.576835632324219 -2736,2736,N168C,-0.01325563,-0.012540208999999998,-0.048363623,-0.045854346,-1.797003822,-0.000978153,0.008471856,-0.034983115,,-0.017456994,-0.007623423000000001,-0.057016313,-0.039710933,0.038708237,-0.13041692800000002,-1.430731547,-2.163276097,0.5555748979999999,1.3170926170000001,-14.00026411,-11.64569988,-18.21824418,-13.32504812,-12.911458099999999,-13.90087027,-11.6279856,-9.458422852,-11.483417510986328,-14.6016845703125,-13.422295570373535,-13.366175651550293,-11.662424087524414 -2737,2737,N168E,-3.87e-05,0.00361849,-0.031139855,-1.7639056359999998,-2.469443095,-0.096990281,0.0015094020000000002,-0.001586755,,0.008690409,-0.00145343,-0.040304768,-0.021974941,-1.7257280369999999,-1.8020832340000001,-2.520799312,-2.418086878,0.663799748,0.684787363,-10.86717465,-8.780377304,-16.44189691,-10.96307677,-9.761955612000001,-8.388566635,-7.8519169579999994,-1.686690935,-11.56639289855957,-14.555123329162598,-14.263447761535645,-14.318325996398926,-12.528724670410156 -2738,2738,N168D,-0.016348783999999998,0.013938262,-0.004908568,0.013362128000000001,-2.229169043,-0.06907743200000001,-0.040028911,0.007331343000000001,,0.003093694,0.024782829,-0.02548714,0.015670003999999998,0.016728998000000002,0.009995258,-1.9488410530000002,-2.509497032,0.730867898,1.300021603,-7.233015862999999,-7.343699432,-9.151473084,-7.307486145,-7.624983475,-4.73743718,-6.998195142999999,-2.41321309,-10.014822006225586,-8.996195793151855,-12.467512130737305,-12.291131973266602,-11.370092391967773 -2739,2739,N168G,-0.012749712,0.004006979,-0.04231318,-0.012899643,-0.188527075,0.15916433,-0.017537861999999998,-0.007961560999999999,,0.022703462,-0.014689503999999999,-0.048097811,-0.036528549,0.004758706,-0.030557992000000003,-0.1951113,-0.18194285,1.4975640069999998,2.203057435,-7.574360086,-4.861448395,-12.30845545,-7.189318137999999,-7.477850639,-6.034727806,-5.897142595,-3.2108338869999997,-10.560959815979004,-13.70171070098877,-10.1019868850708,-13.502835273742676,-12.511594772338867 -2740,2740,N168F,-0.036188077,-0.02869126,-2.1760101990000003,-2.138915059,-3.154169562,-0.018014429,-0.022340332999999997,-0.05003582,,-0.008105856,-0.049276664000000005,-2.199173629,-2.1528467680000003,-1.966683135,-2.311146982,-2.8866931460000003,-3.421645977,-0.131676896,-0.31331940399999997,-12.48331656,-11.31033557,-18.82047555,-9.760250328,-9.90349913,-12.62202223,-8.151712283,-3.160304572,-13.599678039550781,-15.83768367767334,-15.294281005859375,-16.603086471557617,-13.504523277282715 -2741,2741,N168I,-0.030299376,0.011996325,-0.05860076400000001,-0.660491721,-3.003262056,0.034643257000000004,0.019767143,-0.08036589400000001,,0.04412201599999999,-0.020129367,-0.045647692999999996,-0.071553835,-0.569083883,-0.751899559,-2.8782599789999996,-3.128264132,0.737905638,0.828501829,-11.73072959,-9.761129509,-20.05451836,-11.14786073,-9.915852829,-7.774286537,-8.382528459,-4.441771364,-10.452444076538086,-12.2509183883667,-14.342723846435547,-13.6703519821167,-10.249171257019043 -2742,2742,N168H,0.00226338,0.034605168,-0.016642731,-1.940330186,-2.696715137,-0.000837478,0.018089136000000002,-0.013562376999999999,,0.039432867999999996,0.029777467000000002,-0.039498037,0.006212576,-1.790872518,-2.089787854,-2.318082161,-3.075348113,0.613076965,0.677220232,-10.61410474,-9.311944298,-14.52147174,-10.151797,-9.797473167,-9.287837486,-7.711861316,-1.935051848,-9.479499816894531,-12.431886672973633,-10.982588768005371,-11.883520126342773,-10.701858520507812 -2743,2743,N168K,-0.014803562,-0.081029332,-1.417230798,-1.921767634,-2.398846159,-0.034044146000000004,0.0015303060000000002,-0.031137428999999998,,-0.013153307,-0.148905356,-1.4150791090000001,-1.4193824869999998,-1.9172741709999999,-1.926261096,-2.6032009769999997,-2.194491341,2.774563298,1.23616369,-9.462417322,-8.870437248,-11.11032845,-9.763515137,-9.129233467,-8.438572304,-8.089901953,-2.142169553,-11.078816413879395,-12.810413360595703,-13.266044616699219,-14.966389656066895,-10.953713417053223 -2744,2744,N168M,-0.039988353,0.052027116,-0.040947177,-0.750830269,-3.19008805,-0.047542327999999995,-0.016914491,-0.063062215,,0.09776131199999999,0.006292919,-0.016877244,-0.06501711,-0.72662886,-0.775031678,-2.893793487,-3.486382612,0.543112768,0.759878215,-11.60186373,-10.09000655,-15.90326514,-11.78889699,-9.566489647000001,-10.66066033,-7.989281047,-4.557547276,-9.575151443481445,-12.270228385925293,-14.403287887573242,-15.378311157226562,-9.431995391845703 -2745,2745,N168L,-0.012061582,0.040232698,-0.0157709,-1.9264981730000001,-3.2022247989999997,0.022518742,0.000942265,-0.025065429,,0.048384747,0.032080648999999996,-0.016637391,-0.014904408000000001,-1.7803300969999998,-2.072666249,-2.7283688319999997,-3.676080766,0.426496676,0.672897152,-10.71272261,-9.220646628999999,-14.66185291,-11.71016505,-9.79449485,-8.176453606,-7.925686445,-3.257321755,-11.029528617858887,-13.874573707580566,-14.855727195739746,-15.7399263381958,-11.616594314575195 -2746,2746,N168Q,0.009936038000000001,-0.009388160999999999,-0.033667106,-0.0072938840000000005,-1.962057184,-0.072495285,0.0009637789999999999,0.018908297,,0.00751424,-0.026290562000000003,-0.043939623,-0.023394587999999997,-0.0037316690000000004,-0.010856099,-1.8077925430000001,-2.116321824,0.705691073,1.306688555,-10.56402587,-8.25310379,-12.71518896,-11.40839144,-9.895582031,-10.54786311,-6.2814296579999995,-1.861619819,-10.523845672607422,-13.878096580505371,-13.691750526428223,-15.195612907409668,-12.294696807861328 -2747,2747,N168P,-0.022543257999999997,-0.053302765,-1.893528171,-2.1196026690000003,-2.963152876,0.096662916,0.0027722579999999997,-0.04785877400000001,,0.039615855,-0.146221384,-1.967007568,-1.8200487730000001,-1.9977585080000002,-2.24144683,-2.6747304709999997,-3.25157528,0.18946537,-0.12401152800000001,-13.40059995,-11.10473385,-20.53084682,-12.63365673,-12.43498397,-10.2987784,-7.467804887000001,-2.978160861,-12.747060775756836,-16.242706298828125,-15.792403221130371,-17.6655330657959,-12.711838722229004 -2748,2748,N168S,-0.022687142,0.013039978,-0.056499956,-0.024092476,-0.9586709440000001,-0.098234324,-0.019178851,-0.026195432,,0.02993794,-0.003857984,-0.063967312,-0.049032599999999996,0.011596142,-0.05978109400000001,-0.750897956,-1.1664439309999999,0.777474062,1.399002391,-6.071191643,-4.453283234,-8.356821259,-6.044899185,-6.951778618,-4.549175919,-4.9736915139999995,-2.300417911,-8.107301712036133,-9.920272827148438,-10.843498229980469,-10.306282997131348,-8.274087905883789 -2749,2749,N168R,0.007559675,0.012341681,-0.037646281000000004,-1.4903336919999999,-2.367051715,-0.06163486,0.027784947999999997,-0.012665599,,0.014489463999999999,0.010193897,-0.03317113,-0.042121432,-1.290999049,-1.689668334,-2.1732205,-2.56088293,2.251028355,1.4455556509999998,-13.25856069,-10.63524261,-20.23337785,-11.79845706,-11.98309607,-11.64262983,-7.783224854,-3.235316816,-13.348755836486816,-15.519110679626465,-13.947158813476562,-15.450820922851562,-12.581501007080078 -2750,2750,N168T,0.021947928,0.022445983,-0.002035756,0.016570587,-1.293284521,-0.004696055,0.036356236,0.007539619,,0.023988056,0.02090391,-0.02548714,0.021415629,0.025294316,0.007846856999999999,-1.212082488,-1.374486554,0.636832294,1.332523842,-6.951776915,-4.4229756469999995,-10.87258549,-6.926874718,-6.748291328,-5.788157394,-5.559235751,-2.635500592,-8.978974342346191,-10.458929061889648,-10.19145393371582,-10.964795112609863,-8.23509693145752 -2751,2751,N168W,-0.031114617999999997,-0.007513700999999999,-1.021455737,-2.101124509,-2.5586823030000003,-0.007068141,-0.010373081,-0.051856154,,0.031132326000000002,-0.046159728,-0.92742454,-1.115486933,-1.625462281,-2.576786736,-2.1290488780000003,-2.988315727,3.556933064,2.2900382130000003,-14.18874816,-12.68971303,-21.38017712,-11.98573254,-12.41764028,-12.47047782,-9.272486792,-5.834570982000001,-15.346830368041992,-17.64361572265625,-16.433364868164062,-18.58737564086914,-15.458565711975098 -2752,2752,N168V,-0.036888832999999996,0.013501684,-0.020325594,-0.013474015,-2.083815125,0.011870186000000001,-0.023684443,-0.050093223,,0.010534466999999999,0.016468901,-0.009389774,-0.031261414,0.021047171,-0.047995200999999994,-1.8009547380000002,-2.366675511,0.622444378,1.304458249,-11.02579138,-8.915292519,-19.31251488,-9.910659874,-9.139690224,-7.850799393,-7.495717177,-3.0614458210000004,-10.340664863586426,-12.743913650512695,-14.83029556274414,-13.551814079284668,-10.802227973937988 -2753,2753,N168Y,-0.012523528,-0.21304340300000002,-1.70179649,-1.97689715,-2.451047804,-0.052862982,-0.007959648,-0.017087408000000002,,-0.13621018199999999,-0.289876623,-1.515299571,-1.888293409,-1.746566369,-2.207227931,-2.026727829,-2.875367778,4.137193597,2.5774732769999997,-13.26626471,-12.16046127,-20.79598386,-10.28164162,-9.793434784,-13.29980202,-7.945561959,-2.920175397,-12.495504379272461,-14.61918830871582,-14.320680618286133,-15.326629638671875,-11.772171974182129 -2754,2754,E169A,-0.013146613,-0.027920057999999998,0.013182038,0.032935587,0.011510119,0.006481969000000001,-0.011517521999999999,-0.014775703999999999,-0.0049553259999999995,-0.03267412,-0.023165996,0.011726273,0.014637802,0.025267848,0.040603326,-0.0069178569999999995,0.029938094,1.113877919,2.622313949,-5.425133617999999,-5.084872612,-5.823355362,-6.278298256,-5.023430412,-4.915711449,-4.614855783,-0.869946311,-5.438561916351318,-9.758869171142578,-4.726700305938721,-4.992236137390137,-5.827670097351074 -2755,2755,E169C,-0.044431463,-0.076521512,-0.030147797999999996,0.016529485,-0.23286086,0.153985829,-0.07782533900000001,-0.011037587,0.07927302900000001,-0.040166881,-0.11287614300000001,-0.037949402,-0.022346192999999997,0.042533344,-0.009474375,-0.224149142,-0.24157257699999998,1.272019361,1.9843176230000001,-10.78731823,-10.87660532,-11.29960007,-10.76334898,-10.72244277,-10.274594,-8.906941512000001,-6.470511875,-8.038501739501953,-14.483503341674805,-8.378721237182617,-8.102664947509766,-7.8992109298706055 -2756,2756,E169D,-0.117932285,-0.055504745,-0.078598005,-0.012707439,-0.048479077,0.068240287,-0.06462208,-0.171242489,-0.071032834,-0.07859567,-0.032413818999999996,-0.073548938,-0.083647072,-0.020452783000000002,-0.004962095,-0.074395664,-0.02256249,1.35092152,2.335706408,-4.895813481,-5.904384468,-4.861368973,-3.46307386,-5.779126335,-4.47111377,-4.4466693710000005,-1.15204545,-5.194692611694336,-8.142513275146484,-5.8655219078063965,-4.661585330963135,-6.538565635681152 -2757,2757,E169G,0.004134853,-0.029662321000000002,-0.003889637,0.003928237,-0.020031158,0.050376515999999996,-0.014144148,0.022413854,0.011000949,-0.037607575,-0.021717067000000003,-0.027503386,0.019724112,-0.005201187,0.01305766,-0.07398067,0.033918355,1.42174823,2.52135041,-8.441202373,-7.957720696,-7.412193405,-9.925747925,-8.321731482999999,-8.588618355,-6.289660337999999,-2.409301656,-6.796398639678955,-11.747800827026367,-6.694752216339111,-5.933281421661377,-7.077723503112793 -2758,2758,E169F,-0.054640235,-0.027866085,-0.032521503,0.0006438209999999999,-0.224830355,0.477489924,-0.063176471,-0.04610399900000001,0.048538412,-0.049743731,-0.0059884380000000004,-0.034460207,-0.030582799,0.033747459,-0.032459818,-0.181725308,-0.267935402,1.554838161,2.2813231,-9.237172414,-10.43910875,-11.45598996,-6.87928054,-8.529064598,-8.882418221,-6.242579782999999,-3.987417858,-8.44907283782959,-13.654301643371582,-7.749038219451904,-6.938368320465088,-7.977848052978516 -2759,2759,E169I,-0.040801242,-0.06526406,-0.078477533,-0.050810062,-0.251659858,0.37218655100000003,-0.06984687099999999,-0.011755613,-0.023693974,-0.044489962,-0.086038158,-0.016938198,-0.14001686800000002,-0.014070771000000001,-0.087549352,-0.202314875,-0.301004841,1.354273407,2.091480687,-9.423099571,-9.998399757,-11.65209348,-7.563063057000001,-8.640906548,-9.261035019,-5.107877586,-3.279966917,-6.387887954711914,-10.977916717529297,-5.888493061065674,-6.377416610717773,-7.361814022064209 -2760,2760,E169H,-0.013537697,-0.030557822999999998,0.0007459389999999999,0.011691958,-0.09894873,0.186106804,-0.035454348,0.008378954000000001,-0.025054632,-0.033811472999999995,-0.027304172999999998,-0.012991273000000001,0.01448315,0.022186229,0.001197687,-0.150576133,-0.047321326,1.435844083,2.2952099919999998,-6.938597821,-8.722697441000001,-8.019606049,-6.31415818,-7.913842155,-3.72268528,-5.664461507,-2.9558791889999996,-6.206109523773193,-11.653496742248535,-5.599722862243652,-4.7962846755981445,-7.098910808563232 -2761,2761,E169K,-0.040393071,-0.051042555,-0.020801313999999998,-0.001990581,-0.030407853,0.04244703,-0.058810975,-0.021975167,-0.066001089,-0.029846359,-0.07223875099999999,-0.052981438,0.01137881,-0.012263484,0.008282322,-0.053348422,-0.007467284,1.200955754,2.2744598330000003,-7.0053848389999995,-8.797671783,-6.331008995,-7.896524086,-6.960222664,-5.0414966660000005,-5.899231788,-1.621503296,-5.133914947509766,-9.951730728149414,-4.4810791015625,-5.541123390197754,-6.913787364959717 -2762,2762,E169M,0.033258774,-0.003463641,0.029718662000000003,0.011395822,0.021681986,0.028200057999999997,-0.008269683,0.074787231,0.006340732,-0.01084615,0.003918869,-0.0030765590000000004,0.06251388299999999,0.003676408,0.019115235,-0.021945594,0.065309565,1.322020553,2.539203136,-9.331992993,-9.668196526000001,-9.985913588999999,-8.902897858,-8.952965462,-9.149991531,-6.418977655,-4.052849052,-6.964006423950195,-11.3804931640625,-6.558403015136719,-6.598544597625732,-8.457548141479492 -2763,2763,E169L,-0.007609197,-0.05711495,-0.021691306,-0.0034844790000000004,-0.084152105,0.09332073,-0.043331031,0.028112637000000003,0.035366966,-0.058407115999999995,-0.055822783,-0.025963486,-0.017419125,-0.013539006000000001,0.0065700490000000005,-0.099569128,-0.06873508099999999,1.453277929,2.385105567,-8.538693277,-8.754970505,-10.67597267,-7.2629759289999996,-7.941477218999999,-8.058070061,-5.362389916000001,-2.523386368,-6.026703834533691,-9.49759292602539,-5.228370666503906,-6.574273586273193,-7.405570030212402 -2764,2764,E169N,-0.045041810999999994,-0.025481512,-0.039400113,0.002681044,-0.07560792599999999,0.295262565,-0.032926343,-0.057157278,-0.041923844,-0.033148146,-0.017814878,-0.040954321,-0.037845904,-0.022223878,0.027585966,-0.117819047,-0.033396804,1.379760888,2.238939265,-6.058441847,-7.323574767999999,-6.875054176,-4.5302942889999995,-7.094647949,-4.4686380539999995,-5.4323726,-2.576979176,-5.582890033721924,-9.194993019104004,-6.292433261871338,-4.204169750213623,-5.929885387420654 -2765,2765,E169Q,-0.083875059,-0.089191428,-0.033969347000000004,-0.023917543,-0.038255578,0.00332058,-0.074309583,-0.093440535,-0.028028169,-0.090824636,-0.087558219,-0.013583635,-0.054355058,-0.008911804,-0.038923282000000003,-0.062441757,-0.014069398,1.254038725,2.341571275,-2.8874430689999997,-3.446541031,-2.830350899,-3.6185327760000003,-2.676539993,-1.865250649,-3.2125868719999997,-1.686121252,-3.957484483718872,-8.868002891540527,-3.7343978881835938,-3.979940414428711,-6.052404403686523 -2766,2766,E169P,-0.096936527,-0.055726847,-0.020217608,-0.141018043,-2.145505745,0.043369785999999994,-0.074502547,-0.119370506,-0.00089823,-0.03770605,-0.073747643,-0.023924852000000003,-0.016510364,-0.07902097400000001,-0.203015112,-2.046973891,-2.2440375980000002,1.069894943,1.307908514,-9.126873437999999,-9.656727425,-7.430089386000001,-9.695175575,-9.536694115,-9.315680687,-6.042519556,-2.00927826,-9.87251091003418,-15.59687614440918,-7.86124849319458,-8.649975776672363,-11.492998123168945 -2767,2767,E169S,-0.058392850999999996,-0.064887789,-0.037797186,-0.022503406,-0.016386098999999998,0.004409585,-0.069649085,-0.047136617,0.010238465,-0.06127796,-0.068497617,-0.043934372,-0.03166,-0.03262013,-0.012386681,-0.05087649,0.018104292,1.124615063,2.223742174,-3.066955905,-2.662507721,-3.064725456,-4.425564362,-2.497074814,-2.684907173,-2.777340221,-0.489856116,-3.4050710201263428,-7.798995018005371,-4.118375778198242,-2.3673691749572754,-2.2421960830688477 -2768,2768,E169R,-0.034445094,-0.045611207,-0.024138101000000002,-0.003729187,-0.041936411,0.14916386,-0.053449123,-0.015441064,0.006449184,-0.045367887999999995,-0.045854526,-0.03923406,-0.009042142,-0.014258362,0.006799988000000001,-0.091242153,0.007369331,1.432380339,2.3655247619999997,-5.939572345,-8.750249702,-5.629049857999999,-6.963762107999999,-6.282610687000001,-2.072189369,-5.6862078060000005,-0.971105889,-5.407421112060547,-10.909131050109863,-4.276938438415527,-5.552626609802246,-6.643087863922119 -2769,2769,E169T,-0.04344023599999999,-0.05028254,-0.01517074,-0.004772600000000001,-0.028245622,-0.050022255,-0.060416650999999995,-0.02646382,0.018315986,-0.035126712000000004,-0.065438367,-0.018021348,-0.012320132,-0.013929063,0.004383863,-0.037645767000000004,-0.018845477,1.250002193,2.408237251,-4.4607864930000005,-3.216110893,-4.226266548,-5.2839522169999995,-4.965078125,-4.612524681,-3.131633117,-0.727929292,-2.8023393154144287,-8.569869995117188,-2.4727954864501953,-2.428224563598633,-4.2551140785217285 -2770,2770,E169W,-0.028613757000000004,-0.003827443,-0.007942850999999999,-0.015955636999999998,-0.125559554,0.32242019,-0.045701035,-0.011526479,-0.037558497,0.005600701,-0.013255586000000001,-0.027895425,0.012009724,-0.032901463,0.00099019,-0.13555731099999999,-0.115561797,1.4284453030000002,2.263872953,-12.04358384,-12.94824781,-13.43204654,-11.51642675,-11.74650212,-10.57469596,-9.936621472999999,-8.871417516000001,-9.85664176940918,-14.491491317749023,-9.585609436035156,-9.067707061767578,-9.740124702453613 -2771,2771,E169V,0.004141992,-0.044761579,-0.040031474,-0.012339616999999999,-0.136233655,0.260524902,-0.014407304,0.022691287999999997,0.009910995,-0.073964433,-0.015558725,-0.077513412,-0.002549535,-0.041939255,0.017260021,-0.17170775800000002,-0.100759551,1.35170944,2.14145819,-7.9896811329999995,-8.106109734,-10.11983805,-6.062942406,-7.201417801,-8.458097672000001,-5.623025441,-2.403127181,-5.822674751281738,-10.685647010803223,-4.514402389526367,-5.94844913482666,-7.358584403991699 -2772,2772,E169Y,-0.018404298,-0.029936547999999997,-0.038754091000000004,-0.024273212000000002,-0.222237047,0.49526716200000004,-0.01218008,-0.024628516,-0.007669982,-0.04206606,-0.017807036000000002,-0.06210908,-0.015399102,-0.044360729,-0.004185695,-0.252680138,-0.191793955,1.339130369,1.9504885330000001,-8.096605988,-9.803874062,-10.63851283,-5.563165352,-7.780311317000001,-6.697166374,-5.668583919,-3.481176093,-8.316246032714844,-12.923175811767578,-7.566009998321533,-6.875548362731934,-7.511717796325684 -2773,2773,A170C,-0.052773188,-0.096157354,0.081670243,-0.086413306,-0.09577479800000001,0.067317312,-0.07630397400000001,-0.029242402,0.053093260999999996,-0.143113455,-0.049201253,0.011367608999999999,0.151972877,-0.08411425300000001,-0.088712358,0.018314207,-0.20986380300000002,1.25999479,2.58105472,-10.44077623,-11.38113672,-10.68103928,-10.05096712,-9.979572014,-10.11116599,-8.592889901,-5.866684601,-11.590435028076172,-13.391738891601562,-8.81888484954834,-10.097925186157227,-10.56932544708252 -2774,2774,A170E,-0.121502463,-0.06307541900000001,0.022378402999999998,-0.047354243,-1.638338553,0.07678194599999999,-0.06287368900000001,-0.180131237,0.010155439,-0.183231358,0.057080520999999995,0.001886748,0.042870057999999996,-0.036413417999999996,-0.058295067,-1.451702721,-1.8249743840000001,0.748324407,1.324960167,-10.31142313,-11.80940947,-9.454102921,-12.95318264,-8.389646324,-8.950774277,-7.93025815,-3.689510933,-11.025571823120117,-12.335012435913086,-11.527249336242676,-9.60123062133789,-11.446663856506348 -2775,2775,A170D,-0.12075219,-0.116378365,-0.023475747999999998,-0.018752912,-1.2364337859999999,-0.019428551999999998,-0.091515924,-0.149988456,-0.032476619,-0.155673354,-0.077083376,-0.10042847,0.053476975,-0.027146734,-0.010359089,-1.021038868,-1.451828703,0.631843199,1.3449206230000001,-9.92497505,-11.12809231,-8.076365311,-13.81858656,-8.002775932,-8.599055137999999,-7.213962577,-1.9817706069999999,-10.91093635559082,-8.649019241333008,-9.862103462219238,-9.204155921936035,-11.34398365020752 -2776,2776,A170G,-0.032415071000000004,-0.041782677000000004,0.025310166000000002,-0.02862125,-0.06281982900000001,0.006997078,-0.028266423,-0.036563719,0.005474749,-0.110314043,0.026748689,-0.024201425,0.074821757,-0.035454861000000004,-0.021787637999999998,-0.032359822999999996,-0.093279834,1.408082595,2.556899191,-3.998827403,-5.538603202999999,-3.5171929019999997,-4.806930519,-2.907747635,-3.223662758,-5.236393617,-2.506058528,-7.755373954772949,-8.088761329650879,-8.168874740600586,-8.707935333251953,-8.55186939239502 -2777,2777,A170F,-0.046228883,-0.038893992,0.019507549,-0.055667898,-0.379657619,0.55958691,-0.018884077,-0.073573689,0.066094737,-0.125837052,0.04804906900000001,-0.067852941,0.106868039,-0.102150365,-0.00918543,-0.28370070199999997,-0.47561453600000003,1.6481118469999998,2.157419978,-12.13811876,-9.776086876,-14.40156111,-12.56584692,-11.49757026,-12.44952863,-6.655469915,-2.9744858780000003,-11.593247413635254,-12.61190414428711,-11.29240608215332,-7.89957857131958,-9.335315704345703 -2778,2778,A170I,-0.10490715800000001,-0.052635375,0.066169441,-0.031905413,-0.499302942,0.04205438400000001,-0.06675937900000001,-0.143054936,0.003799796,-0.117964626,0.012693877,-0.011143063,0.143481945,-0.021173452000000002,-0.042637374000000006,-0.44777242799999994,-0.550833455,1.260561951,1.709475478,-12.64740321,-12.57925598,-15.80080974,-11.66315922,-11.07511851,-12.11867262,-7.1121191370000005,-3.263873031,-10.445931434631348,-12.248464584350586,-11.042896270751953,-9.454744338989258,-10.638260841369629 -2779,2779,A170H,-0.065961038,-0.054769974000000006,0.015158224,-0.019989411000000002,-0.422100168,0.7117553879999999,-0.066052494,-0.065869581,-0.011520839,-0.078210163,-0.031329785,0.048119397,-0.01780295,-0.000631242,-0.039347579,-0.17581898899999998,-0.6683813470000001,1.151753969,1.9654993630000002,-11.79096771,-13.9413994,-12.67059221,-12.27446781,-10.16410275,-9.904276375,-8.67328071,-5.14187175,-11.086591720581055,-12.7366304397583,-9.101465225219727,-7.8642401695251465,-10.031332015991211 -2780,2780,A170K,-0.18601348399999998,-0.022392553,0.057503161,-0.066294609,-2.138205066,0.123040496,-0.075433113,-0.296593854,0.022355091,-0.142639708,0.09785460300000001,0.070054324,0.044951998,0.030163916000000002,-0.162753134,-1.6972153890000001,-2.579194743,0.5952033210000001,1.306977082,-10.48569397,-13.70631238,-9.503845558,-11.31636265,-9.653880615,-8.248068626,-7.3730556720000004,-3.62545214,-12.129964828491211,-13.452800750732422,-8.99728775024414,-10.341214179992676,-10.063118934631348 -2781,2781,A170M,-0.020488045,0.022837259,0.07187471299999999,-0.022317043999999998,-0.6514387079999999,0.222044188,0.03859571,-0.079571799,0.011356541999999999,-0.018424567,0.064099085,0.038650977,0.10509844800000001,-0.012859223000000001,-0.031774865,-0.603793704,-0.6990837120000001,0.597992691,1.393153012,-13.57327263,-14.12124318,-14.90980766,-13.70247703,-12.633886,-12.49894929,-8.75654738,-5.161878933000001,-10.325804710388184,-12.884522438049316,-11.264750480651855,-8.422928810119629,-10.91230583190918 -2782,2782,A170L,0.006327951,-0.041927394,0.033883849,-0.036705456000000004,-1.003401435,0.10953636,-0.002155978,0.014811878999999998,0.004971412,-0.168503318,0.084648531,-0.068989503,0.13675720000000002,-0.073875734,0.000464823,-0.777766449,-1.229036421,1.264081611,1.5539096909999999,-13.60284708,-13.60104256,-14.91455549,-13.6224366,-13.19736761,-12.67883314,-8.182010365,-4.0588607,-10.797048568725586,-13.22992992401123,-11.266731262207031,-9.511500358581543,-11.143717765808105 -2783,2783,A170N,-0.13138714199999998,-0.027158272999999997,0.028140192,-0.05820261,-0.31425025,0.010971807,-0.031449642,-0.231324642,0.029082811,-0.078150585,0.02383404,0.0037522859999999996,0.052528097999999995,-0.057276793,-0.059128426,-0.265301317,-0.363199182,1.634631889,2.184577605,-7.9692615589999996,-10.72011871,-8.069554794,-9.798834579,-5.469021004,-5.788778709,-5.317546362,-2.12183132,-9.901751518249512,-9.96985912322998,-7.425559043884277,-5.395668029785156,-9.413756370544434 -2784,2784,A170Q,0.027145552000000003,0.069486243,0.08438088199999999,0.0016696810000000001,-1.5851603140000001,0.190289371,0.087083616,-0.032792512999999995,-0.008153514,0.022914105,0.116058381,0.050594502,0.118167261,0.030206892000000003,-0.026867531,-0.981989655,-2.1883309719999997,0.670563404,1.3531055440000002,-11.38778377,-13.23523441,-11.02280081,-13.37741454,-9.830391083,-9.473078026,-7.833888245,-2.8089587989999996,-10.897336959838867,-14.084640502929688,-10.192024230957031,-9.625797271728516,-11.271175384521484 -2785,2785,A170P,0.04309479099999999,0.019750567,0.090874703,0.028561856,-0.502327118,0.693849974,0.024715523,0.061474059000000005,-0.0076101219999999995,-0.058313847,0.09781498,0.034648311,0.147101095,0.026825947000000003,0.030297765,-0.39810587,-0.606548365,0.953934636,1.589823449,-9.760103878999999,-10.21045109,-10.52354304,-9.219587654,-9.673593323,-9.173344292000001,-7.53036986,-4.078761878,-10.629353523254395,-11.929999351501465,-12.50830364227295,-10.91086483001709,-11.011335372924805 -2786,2786,A170S,-0.012677213,-0.065358794,0.075523593,-0.016748596,-0.010849722,0.041644968,-0.056331584000000004,0.030977157999999998,0.036948743,-0.17409524,0.043377652,-0.037498266,0.188545452,-0.047278939000000006,0.013781748,0.004223780999999999,-0.025923223999999998,1.671448915,3.643209181,-4.338230475,-5.460875327999999,-4.222390488,-4.525577087,-3.6482992860000003,-3.834010185,-5.757351579,-2.488701164,-7.516927719116211,-6.88692569732666,-6.501190662384033,-6.6126933097839355,-8.218514442443848 -2787,2787,A170R,-0.058899272,-0.051966162999999996,0.035635582,-0.008292167,-0.9003797020000001,0.265587234,-0.063934458,-0.053864086,-0.025471855,-0.09787018900000001,-0.0060621369999999996,0.016960384,0.05431078,-0.022699077999999998,0.006114745,-0.5862753,-1.214484103,1.037642219,1.525760407,-9.796182004,-11.34121505,-11.08965739,-10.506607,-7.77803212,-8.265398453,-6.900113656,-2.661912079,-12.643178939819336,-13.00704574584961,-8.962491035461426,-9.348352432250977,-11.131787300109863 -2788,2788,A170T,0.01888895,-0.067069146,-0.012372215,-0.014465438999999998,-0.7204056740000001,0.301163232,0.010256826,0.027521074,-0.013352518999999998,-0.16176717,0.027628879,-0.129471485,0.104727055,-0.059001412,0.030070535,-0.542671067,-0.89814028,1.342121253,1.7019444430000001,-7.358760268999999,-8.112083878,-9.172879477999999,-7.571365158,-5.765362366000001,-6.172110466,-6.718838396000001,-3.0857404689999997,-8.312570571899414,-9.745197296142578,-8.343879699707031,-7.834291934967041,-8.866211891174316 -2789,2789,A170W,0.020925604,-0.030874172999999998,0.027723814,0.003772246,-0.21375533100000002,0.40966330799999995,0.014750846000000001,0.027100362000000003,0.005510534,-0.093587555,0.03183921,-0.058755339000000004,0.11420296699999999,-0.069717418,0.07726191,-0.17950503,-0.248005631,1.5915227490000001,2.299623932,-12.549656500000001,-14.727724100000001,-12.0736616,-12.33420898,-12.24720695,-11.36548086,-7.144091575,-3.122589728,-13.739256858825684,-13.845473289489746,-12.754700660705566,-12.112603187561035,-10.736491203308105 -2790,2790,A170V,-0.053605871,-0.03109561,0.045429724000000005,-0.007219354,-0.22716539,0.212341394,-0.055002762999999996,-0.052208979,0.018472688,-0.12246189699999999,0.060270678,0.028668055,0.062191392000000005,0.016174568,-0.030613275,-0.12414011300000001,-0.330190666,1.470164964,2.335729421,-8.372579536,-9.69791011,-12.21688485,-6.91859272,-6.2843833920000005,-6.74512661,-5.809460225,-1.974498799,-8.15736198425293,-9.108710289001465,-8.507433891296387,-5.930617332458496,-7.950736999511719 -2791,2791,A170Y,-0.09593548,-0.091819408,0.038564451,-0.11199079,-0.15246617199999998,0.5295210370000001,-0.10181850199999999,-0.090052458,-0.037726292,-0.153821349,-0.029817466,-0.01460743,0.09173633199999999,-0.11960313,-0.104378449,-0.10518353400000001,-0.19974881,1.4261765569999998,2.282320266,-12.45360946,-11.17721536,-13.40752909,-12.90599371,-11.55923056,-13.21807857,-7.2931944070000005,-3.900950079,-12.525951385498047,-12.805741310119629,-10.716005325317383,-8.363944053649902,-10.050199508666992 -2792,2792,I171A,-0.09631298,0.123721611,0.018986278,-0.067352633,0.019637073,0.100967011,-0.064098513,-0.128527446,-0.078600752,0.22959356,0.017849662,0.22386015199999998,-0.185887597,0.086274873,-0.22098013800000002,0.216932608,-0.17765846300000002,0.937099349,3.1712903160000003,-1.6672240719999998,-1.573439697,-2.4989618,-2.111166183,-1.261580521,-0.89097216,-2.8855025810000003,-0.364511606,-7.04874324798584,-9.231584548950195,-5.826755523681641,-8.78268814086914,-7.9980387687683105 -2793,2793,I171C,-0.20220208899999997,0.10063520199999999,-0.018744358,-0.05918535,-0.033828286,0.024588827999999997,-0.138642336,-0.265761841,-0.018179748,0.176359923,0.024910481,0.188550065,-0.22603878,0.160654745,-0.279025445,0.17904032600000003,-0.246696898,1.087665001,3.101080646,-6.634358015,-6.658246017000001,-7.275842529,-6.75342086,-6.480944999999999,-6.00333567,-6.73479882,-4.16694674,-9.171675682067871,-13.298952102661133,-9.684179306030273,-12.775113105773926,-11.004772186279297 -2794,2794,I171E,-0.039921767999999996,0.154594606,0.04851653,-0.021653235,0.01487968,0.081751542,-0.010234085,-0.069609451,-0.081372888,0.279657579,0.029531632999999998,0.26833736,-0.1713043,0.151801434,-0.195107903,0.262677103,-0.23291774399999998,0.9809544929999999,3.0951721610000003,-3.078656253,-2.830795822,-3.6542754289999997,-3.760824417,-2.9015301669999998,-2.245855431,-3.416629285,-0.8146574659999999,-7.314633369445801,-9.34184741973877,-5.5643181800842285,-7.62038516998291,-7.681852340698242 -2795,2795,I171D,-0.105579122,0.049574337,0.01540961,-0.033377748,-0.095848309,0.099263247,-0.024821131,-0.186337113,-0.083274533,0.225882356,-0.126733682,0.244703077,-0.21388385699999998,0.143456055,-0.21021155,0.107243882,-0.2989405,1.0399613859999999,2.981270359,-5.1252798319999995,-4.120596802,-7.698628677,-5.284847183,-4.243056229,-4.279270271000001,-4.793871306000001,-1.889711446,-8.587661743164062,-10.717907905578613,-6.9488372802734375,-9.924257278442383,-10.290666580200195 -2796,2796,I171G,-0.061039008,0.133327904,0.036276848,-0.028479956,-0.010270764,0.158870544,-0.019094265,-0.10298375,-0.056878736,0.237138602,0.029517206,0.24942474899999997,-0.176871053,0.11493250099999999,-0.171892412,0.219258895,-0.239800423,0.9457758629999999,3.07879746,-4.16947151,-4.3701443410000005,-5.124734833,-4.661456009,-3.891563728,-2.799458641,-4.256685672,-1.9199760819999998,-9.518144607543945,-11.666799545288086,-8.320569038391113,-11.160072326660156,-10.560310363769531 -2797,2797,I171F,-0.126633636,0.213098512,-0.02566361,-0.029540465,0.072452323,0.193212196,-0.035480727999999996,-0.217786543,-0.044191052,0.397135014,0.02906201,0.331382983,-0.38271020200000005,0.22231548199999998,-0.281396411,0.2726206,-0.127715955,1.671448915,3.643209181,-3.434239246,-3.907214386,-2.9650725939999996,-1.8983537519999998,-4.141246384,-4.2593091130000005,-4.545035477,-0.757552022,-7.178221225738525,-9.507142066955566,-7.839010238647461,-9.42547607421875,-9.724457740783691 -2798,2798,I171H,-0.09518807800000001,0.124239645,0.06992852,-0.062571532,-0.076070341,0.219538667,-0.048235825999999996,-0.142140329,-0.055769241,0.200840369,0.04763892,0.28747749699999997,-0.147620458,0.107418684,-0.232561748,0.23912898100000002,-0.391269663,1.081456891,3.3266342860000004,-4.323939069,-4.828925568,-4.291607933,-3.829623985,-4.3647652589999995,-4.3047725980000004,-4.635746769,-1.914659769,-8.077849388122559,-10.402522087097168,-7.482654571533203,-9.31380844116211,-9.195242881774902 -2799,2799,I171K,-0.203857835,0.010062871,-0.013814213999999998,-0.111687403,-0.029810137,0.09286495,-0.161154136,-0.246561534,-0.169200286,0.209314676,-0.18918893399999998,0.166661339,-0.194289766,0.051706823,-0.275081628,0.201323187,-0.26094346,1.020937332,3.080219537,-0.974225342,-1.14402272,-2.254477058,-0.829373238,-0.7694204179999999,0.126166725,-2.7672495969999997,-1.027763009,-6.511907577514648,-8.067745208740234,-6.4613118171691895,-7.198342323303223,-5.101408004760742 -2800,2800,I171M,-0.13282428,0.10719356099999999,-0.032061623,-0.169560513,-0.08432525199999999,0.10912950199999999,-0.053226992,-0.212421568,-0.063419473,0.23862893,-0.024241809,0.258832316,-0.322955562,0.045183996,-0.38430502200000005,0.226451651,-0.395102154,1.148701582,3.230137117,-2.64753745,-2.9867262119999998,-3.507819717,-2.473800102,-2.537389671,-1.731951546,-5.024949405,-2.607687399,-6.5420145988464355,-8.356087684631348,-7.232714653015137,-7.716564178466797,-7.556582450866699 -2801,2801,I171L,-0.053029779000000006,0.168472901,0.059931007,-0.027830146,0.009850653000000001,0.029297893,-0.012498256999999999,-0.093561301,-0.055530389000000006,0.282488665,0.054457137,0.288892415,-0.16903040100000002,0.134323106,-0.189983398,0.281113008,-0.26141170199999997,0.8597312840000001,3.121536077,1.0263578000000002,0.287215218,1.2787992479999999,2.031100266,0.647093887,0.887580383,0.08859719699999999,0.199035965,-5.30375862121582,-6.639397621154785,-5.35989236831665,-6.7643890380859375,-6.777475357055664 -2802,2802,I171N,-0.117746345,0.10418231900000001,0.035746762,-0.047183872,-0.006277549,0.135208309,-0.065961348,-0.169531342,-0.152261864,0.217230785,-0.008866148,0.21408598899999998,-0.142592466,0.13281458599999998,-0.22718233,0.22581787600000003,-0.23837297300000002,0.938734757,3.1088297110000003,-4.245105354,-3.8611394039999998,-4.668823608,-4.565625839,-4.267959625,-3.8619782939999996,-4.362628681,-2.489208616,-7.7238054275512695,-7.710139274597168,-7.247297763824463,-9.197488784790039,-8.416816711425781 -2803,2803,I171Q,-0.136780133,0.15140254,0.051563801,-0.045629091,-0.016285197,0.079487315,-0.100173568,-0.173386698,-0.021028894,0.319744676,-0.016939597,0.312133043,-0.20900544100000001,0.17027892600000002,-0.261537108,0.261245422,-0.293815815,1.543610422,3.106887046,-3.177733354,-2.9495476380000003,-4.291876266,-3.722390068,-2.456833984,-2.468018814,-3.879974675,-1.38447674,-7.379179954528809,-8.862069129943848,-6.26362419128418,-7.98716926574707,-7.255033493041992 -2804,2804,I171P,-0.050206258,0.1580078,0.08654697900000001,-0.032749403999999996,-0.622117062,0.385792779,0.005079394,-0.10549191,-0.055715550999999995,0.256918148,0.059097450999999995,0.267297332,-0.094203374,0.092493311,-0.15799211900000001,-0.25651028800000003,-0.9877238359999999,0.8795694629999999,1.7084101580000002,-4.046796228,-4.3757248230000005,-6.01796096,-4.0153571239999994,-3.6621448439999997,-2.1627933880000003,-4.828722397,-0.660251418,-8.460711479187012,-10.594965934753418,-8.870341300964355,-11.16621208190918,-9.775728225708008 -2805,2805,I171S,-0.066464517,0.09545875599999999,0.020383314,-0.030746639,0.007955541,0.161989052,-0.016627085,-0.116301948,-0.056002404000000006,0.222523897,-0.031606385,0.24523530100000002,-0.204468674,0.068267565,-0.12976084300000001,0.1495418,-0.133630718,1.046618325,3.208839672,-3.0940859360000004,-3.052564186,-3.742313171,-3.4594869,-3.0558786469999997,-2.160186775,-3.058052722,-1.143411892,-7.59951639175415,-9.105518341064453,-7.23798942565918,-9.180076599121094,-8.809836387634277 -2806,2806,I171R,-0.088703603,0.118916887,0.041168408999999996,-0.026153707,0.007069098,0.071385272,-0.061478599,-0.11592860599999999,-0.033245416,0.235205655,0.002628118,0.254470718,-0.1721339,0.138340256,-0.19064767,0.244125896,-0.22998770100000002,0.9534124959999999,3.162273815,-1.4678639180000002,-1.367263748,-2.3968422240000002,-2.139248489,-1.013394325,-0.422570801,-2.735783614,-0.522473437,-6.9407267570495605,-9.201338768005371,-6.993858814239502,-6.995920181274414,-6.652523040771484 -2807,2807,I171T,-0.02400513,0.180240328,0.082866377,-0.020739307,-0.012082141000000001,0.171668552,0.041556092,-0.08956635199999999,-0.023871762,0.295898377,0.06458227799999999,0.305764256,-0.140031502,0.12879652,-0.170275134,0.268413272,-0.292577553,0.926636351,3.060451591,-0.5732387179999999,0.500868126,-1.8677338030000001,-1.8347046130000002,0.077572639,0.257804062,-2.07455144,-0.45702996799999995,-5.247796535491943,-6.986816883087158,-5.199428558349609,-6.16816520690918,-6.2698493003845215 -2808,2808,I171W,-0.025844596,0.140569231,0.054273255,-0.007553621999999999,0.011755136000000001,0.097088625,0.026553676000000002,-0.07824286700000001,-0.024969222000000003,0.23647427899999998,0.044664182999999996,0.256343515,-0.147797006,0.12113960300000001,-0.136246847,0.21227354399999998,-0.18876327199999998,1.671448915,3.643209181,-6.475497278,-6.831224152000001,-7.058029472,-5.848274979,-6.127106827,-6.51285096,-5.753042872000001,-0.620947563,-9.119227409362793,-12.219281196594238,-10.085979461669922,-11.546107292175293,-11.740309715270996 -2809,2809,I171V,-0.119862614,0.11045665699999999,0.022800402999999997,-0.042349437000000004,-0.011763923999999999,0.08276876799999999,-0.056777793,-0.182947435,-0.07504464400000001,0.211230685,0.009682628,0.267117468,-0.221516663,0.12038860900000001,-0.205087482,0.21212398899999999,-0.235651836,0.997357017,3.08446084,-1.184860056,-1.0651610409999999,-1.460971931,-1.950264725,-0.898380905,-0.549521675,-2.7009712880000003,-0.430870839,-4.3125386238098145,-7.093904495239258,-5.570400238037109,-5.893775939941406,-5.496387481689453 -2810,2810,I171Y,-0.13774284,0.11234123900000001,0.019757903,0.006720588,0.049878287,0.139107693,-0.08853253800000001,-0.186953142,-0.016730053999999998,0.255627176,-0.030944698,0.26345251399999997,-0.223936708,0.21758382199999998,-0.20414264699999998,0.35755154899999997,-0.257794975,1.014288975,3.3338518930000003,-5.022214557,-5.769217133,-3.248272949,-4.71504686,-5.598350494,-5.780185349,-5.131600893,-0.170870913,-7.7440185546875,-11.23377799987793,-8.252596855163574,-9.205403327941895,-10.019445419311523 -2811,2811,P172A,0.001117875,0.002953297,-0.006095496999999999,0.022475883,-0.054554334,0.040140858,-0.0054887009999999995,0.00772445,0.019277943,0.015655931,-0.009749337,0.005751358000000001,-0.017942351000000002,0.044389895,0.000561871,-0.044741645,-0.064367023,1.231996208,2.442412546,-4.184918288,-4.363418381000001,-4.8424460830000005,-4.257608513,-3.4990720439999996,-3.962046417,-6.062814759,-1.7377040730000002,-7.467360496520996,-7.8427510261535645,-6.369163513183594,-7.953984260559082,-7.454631328582764 -2812,2812,P172C,-0.07696613299999999,-0.040921808,-0.010724445,-0.035253481,-0.232375688,0.033277222999999995,-0.076007113,-0.077925153,0.08426145300000001,0.002409814,-0.084253429,0.038859607000000004,-0.060308497,-0.008915731,-0.06159123,-0.122154394,-0.342596981,1.330674272,2.241012084,-10.34097992,-10.69435436,-11.749934800000002,-10.67926831,-9.390919685,-9.190422462,-11.019847300000002,-8.034165643,-13.074729919433594,-15.095766067504883,-12.660957336425781,-13.695230484008789,-14.344106674194336 -2813,2813,P172E,0.001968066,0.001442035,-0.022126802,0.02185824,0.013131383,0.047142548,-0.009442131999999999,0.013378263999999999,0.011018408,0.030556952000000002,-0.027672883,-0.025078303,-0.0191753,0.038753824,0.004962655,-0.014126159,0.040388924,1.5464736069999998,2.938183126,-5.779987203999999,-6.171462502000001,-6.462473152,-6.00425502,-5.002051796,-5.25969355,-6.166718781,-1.4663134709999999,-8.122693061828613,-9.743027687072754,-8.01844596862793,-10.401246070861816,-8.449962615966797 -2814,2814,P172D,0.0019527070000000001,-0.082176293,-0.06239503,-0.068523337,-0.162923428,0.103830401,0.007719485,-0.0038140709999999996,0.006812686,-0.065372523,-0.098980062,-0.05650614599999999,-0.068283913,-0.072608718,-0.06443795599999999,-0.08508599,-0.240760865,1.3550698,2.3000461480000003,-6.691720938,-5.931287666,-8.411797234,-6.470429413,-6.4959942470000005,-6.14909613,-5.814514602999999,-1.030554757,-9.177858352661133,-10.658674240112305,-9.20268726348877,-11.422859191894531,-10.58410358428955 -2815,2815,P172G,0.011769867,-0.020191912,-0.01692597,-0.023617415,-0.29261040000000005,0.19001301,0.01312699,0.010412743,0.024247391,-0.019344609,-0.021039214,-0.028432613,-0.0054193259999999995,-0.019351301,-0.027883529,-0.230312333,-0.35490846600000003,1.658533535,2.263259212,-7.077279787999999,-7.402169594,-8.359193871,-7.290476418,-6.119342833999999,-6.215216225,-7.521392221,-3.313578728,-10.330702781677246,-11.671866416931152,-8.941193580627441,-11.914399147033691,-11.119749069213867 -2816,2816,P172F,-0.019773916000000002,-0.004722398,-0.021259545,-0.018058491,-0.209981855,0.035778912999999996,-0.036455581,-0.00309225,-0.017661083,-0.015004597,0.005559801,-0.002258296,-0.040260792999999996,-0.010472129,-0.025644852000000003,-0.169047753,-0.25091595699999997,1.544516459,2.29839057,-10.26263951,-10.68089321,-12.48024335,-10.90829728,-8.520697418,-8.723066292,-9.198343392,-6.156125901,-10.495552062988281,-12.086014747619629,-9.974142074584961,-10.467344284057617,-11.180198669433594 -2817,2817,P172I,-0.107478003,-0.109593588,-0.155593595,-0.102566746,-0.179605393,0.018884004,-0.104544741,-0.110411265,0.007633354,-0.075410433,-0.14377674199999999,-0.09229746900000001,-0.218889721,-0.08910832199999999,-0.116025169,-0.182890534,-0.17632025199999998,1.5665437830000002,2.239060652,-6.840779039,-7.644942154,-7.6711853560000005,-7.601037819,-5.123333809,-6.163396057000001,-7.012814838,-3.997347323,-9.105310440063477,-10.307801246643066,-10.34319019317627,-10.427231788635254,-8.633170127868652 -2818,2818,P172H,0.078248106,0.005676646,-0.0030090140000000004,0.060013897999999996,-0.099280105,0.037115569,0.08689524,0.069600972,0.045825175,-0.039116498,0.05046979,-0.029967285,0.023949257,0.000982995,0.11904480099999999,-0.146234959,-0.05232525,1.233807273,2.081520001,-7.895547705,-8.447533768,-10.313887699999999,-7.395786018,-7.007332916,-6.313198128,-7.452325407999999,-3.656322212,-9.474942207336426,-10.882515907287598,-9.59079647064209,-10.754592895507812,-9.755615234375 -2819,2819,P172K,-0.069295913,-0.02546872,-0.012185338,-0.02600526,-0.150293483,0.061738815999999995,-0.061533097,-0.07705872799999999,0.037856245,0.039312171,-0.09024961,0.017291669,-0.041662345,0.002003096,-0.05401361599999999,-0.063209806,-0.23737715899999998,1.3065021479999999,2.41036893,-4.889110747,-6.0849689410000005,-4.254709175,-6.044946982999999,-4.3294653169999995,-3.7314633180000003,-6.606969952,-1.797037565,-7.965797424316406,-9.86351203918457,-8.62341594696045,-10.576608657836914,-7.0576934814453125 -2820,2820,P172M,0.016380443999999997,0.006183593,0.027069726000000002,0.005683074000000001,-0.063852169,0.041613358999999996,0.019783055,0.012977833000000001,0.08472526699999999,0.021510195,-0.009143009,0.012887692,0.04125176,0.01167293,-0.000306782,-0.11317641099999999,-0.014527926000000002,1.325568531,2.276970377,-7.30287317,-8.204166183,-8.82109285,-8.740728683,-5.507420311000001,-5.240957825,-7.46083837,-4.123267578,-10.422195434570312,-11.679388046264648,-11.513669967651367,-11.639805793762207,-10.978130340576172 -2821,2821,P172L,-0.013239043,-0.012600623,-0.008347555999999999,0.013031208,-0.088987201,0.045285132,-0.016003924,-0.010474161999999999,-0.008864002,0.015493691,-0.040694936,0.009441395,-0.026136506,0.04392932099999999,-0.017866905,-0.06366941,-0.114304992,1.3247381040000001,2.446562814,-5.328741733999999,-5.797363373,-6.869375175,-6.456270546,-3.9210318369999997,-3.59966774,-5.530288904,-2.202995031,-8.140544891357422,-9.02110481262207,-8.4656343460083,-9.12078857421875,-8.166810035705566 -2822,2822,P172N,-0.022093703,0.031018935,-0.006068476,-0.023893327000000002,-0.170574423,0.136605588,-0.005995673000000001,-0.038191733,0.026153252000000002,0.013900105,0.048137764000000006,0.041208662,-0.053345613,-0.037186115,-0.010600538,-0.192735469,-0.14841337599999999,1.276463678,1.982014116,-7.211386871,-7.369155075,-8.078953957000001,-8.234123947,-6.789147095,-5.585554283,-7.9983154910000005,-2.695125687,-9.944981575012207,-11.690378189086914,-10.539769172668457,-12.117696762084961,-10.967074394226074 -2823,2823,P172Q,0.018725474,0.003644287,-0.039118791,-0.045657909,-0.06438121599999999,0.007023506999999999,-0.036191491,0.073642439,0.03482979,-0.008019714,0.015308287,-0.057433949000000005,-0.020803633000000002,-0.07875695099999999,-0.012558866,-0.079353946,-0.049408485999999995,1.380362695,2.33842162,-5.748854113999999,-6.811698448,-6.159942566000001,-5.824483391,-4.792270454,-5.15587571,-6.688081261000001,-2.453653873,-9.099664688110352,-9.52416706085205,-8.902339935302734,-10.454792976379395,-8.494258880615234 -2824,2824,P172S,-0.011998831000000001,-0.020994856,-0.031657725,-0.029486734,-0.142501876,0.04294368,-0.037138929,0.013141268000000001,-0.001029218,-0.043079157,0.001089446,-0.046502500999999995,-0.016812949,-0.018540195,-0.040433273,-0.137355525,-0.147648226,1.318005127,2.1425803969999997,-5.426282378,-5.737481026,-5.927299522,-6.0058177189999995,-4.714068672,-4.746744949,-6.542918154,-2.677748152,-7.7314653396606445,-8.942936897277832,-7.742632865905762,-9.24409294128418,-8.738922119140625 -2825,2825,P172R,-0.032054837,-0.032427656,-0.032357698,-0.028632402,-0.19472374899999997,0.097271059,-0.026794883,-0.037314791,-0.009618363000000001,-0.021264424,-0.043590887,-0.049636055,-0.01507934,-0.03352142,-0.023743383,-0.153306189,-0.236141308,1.5383968190000001,2.305254609,-5.98171881,-6.366349266,-8.162817741,-5.58078141,-5.054556938,-4.744088692,-6.929385623,-2.19294624,-8.386216163635254,-9.718234062194824,-8.725375175476074,-9.63747501373291,-8.232805252075195 -2826,2826,P172T,-0.034828631,0.018208693999999997,-0.019928028,-0.018340461000000002,-0.091111296,0.07525266,-0.029939896,-0.039717366000000004,0.035008402,0.006623466,0.029793922,-0.019088669,-0.020767386000000002,-0.004696119,-0.031984803,-0.10470023699999999,-0.077522355,1.375364729,2.330075134,-5.941827704,-5.975063469,-6.9239668960000005,-6.212816642999999,-4.976660202,-5.62063131,-6.708227152999999,-3.1508456739999997,-7.187511920928955,-9.718682289123535,-8.842082023620605,-10.051759719848633,-8.558259010314941 -2827,2827,P172W,0.002994454,-0.006930095,-0.021457196,-0.013916623000000001,-0.276195727,-0.000691368,0.006030806999999999,-4.1899999999999995e-05,-0.025062097999999998,0.019369773,-0.033229962,0.0023011729999999997,-0.045215565,-0.003084136,-0.02474911,-0.207077048,-0.345314406,1.33877029,2.082277416,-10.16215466,-10.48194019,-12.54818049,-10.31205666,-8.907524437000001,-8.561071502999999,-9.458007638,-5.9335892999999995,-12.874465942382812,-13.893641471862793,-12.124297142028809,-12.55526065826416,-12.18366813659668 -2828,2828,P172V,-0.029239919,-0.008407592,-0.004568361,-0.028244098999999998,-0.09745996900000001,0.043234017,-0.033917556,-0.024562281000000002,0.03931267,-0.00798717,-0.008828014,-0.003608428,-0.0055282940000000004,0.012968047,-0.069456244,-0.071663629,-0.12325630800000001,1.20163706,2.221100871,-6.088387537999999,-7.051690605,-6.695140991000001,-6.544233352999999,-4.257088974,-5.893783768,-7.076851192,-3.1396178989999997,-8.468003273010254,-9.695686340332031,-9.05140209197998,-9.755842208862305,-8.471067428588867 -2829,2829,P172Y,-0.026845326,-0.042793402,-0.025758065,-0.042041594,-0.19954440899999998,0.068970135,-0.017117611,-0.036573041,0.067677013,0.003911404,-0.089498207,0.017136231000000002,-0.06865236,-0.035796611,-0.048286577000000004,-0.18737374,-0.211715078,1.45179385,2.174120846,-8.503719482000001,-8.822316795,-11.73148089,-8.593373238,-6.683565475,-6.687861015,-7.368743381,-2.546249666,-11.104592323303223,-12.91758918762207,-10.773128509521484,-11.18466567993164,-11.097494125366211 -2830,2830,N173A,0.006717756,0.037353923,0.015937926,0.004064735999999999,0.013932702,0.030829309,0.053005352,-0.03956984,0.015424618000000001,0.057293893,0.017413953,-0.047528339,0.07940419,0.000709052,0.007420419,-0.029112952,0.056978355,1.349032761,2.537183893,-1.5775492480000002,-1.936636597,-1.78372702,-1.173321899,-1.6168311919999998,-1.37722953,-2.61833548,0.954854938,-4.954195022583008,-5.897387504577637,-5.928424835205078,-4.724189281463623,-4.9499192237854 -2831,2831,N173C,0.0014393960000000001,-0.021186905,0.005098947,0.00135119,-0.014365243,-0.032295283,-0.00448532,0.007364112,-0.032948717,0.018375827,-0.060749635999999996,-0.035893272000000004,0.046091165999999996,-0.030368917000000002,0.033071297,-0.053451128,0.024720642999999997,1.308310082,2.407821952,-5.8069044860000005,-5.884991966,-6.572581047000001,-5.845441872,-6.343238541,-4.388269005,-6.669226787,-3.839370534,-8.121557235717773,-9.829391479492188,-8.613149642944336,-7.819931507110596,-7.409910678863525 -2832,2832,N173E,0.007260559000000001,-0.005198744,-0.024207679,-0.009863304,-0.008709017,-0.0036405,-0.006385892,0.020907009,0.016133178,-0.047982624,0.037585136,-0.073467091,0.025051734,-0.034399282999999996,0.014672676,-0.043144978,0.025726945,1.4145505619999998,2.455773264,-2.33825419,-2.512686981,-1.576178078,-2.488184563,-3.47100676,-1.643214569,-4.272080084,-0.380742051,-4.459377765655518,-6.233869552612305,-5.890146732330322,-4.975733280181885,-5.545249938964844 -2833,2833,N173D,-0.028956548,-0.0071130080000000005,-0.018001773000000002,0.001731535,-0.029921061000000002,-0.032295685,-0.057270647,-0.000642448,0.044087815,-0.002374712,-0.011851303999999998,-0.01524408,-0.020759465,0.029530732,-0.026067662000000002,-0.015468124,-0.044373997000000005,1.216995399,2.621633422,0.32512818600000004,0.77216433,-0.244569008,0.339980331,0.161853111,0.596212166,-2.139559444,0.274190508,-3.6134767532348633,-4.192749977111816,-4.539003849029541,-4.006350040435791,-4.130241870880127 -2834,2834,N173G,0.009624825,-0.013039997,-0.00323681,-0.002602129,-0.0016216610000000002,-0.053431259,-0.010171811,0.02942146,0.029019918999999998,-0.021075361,-0.005004632,-0.035354312,0.028880692000000003,-0.019126617,0.01392236,-0.021595327,0.018352005,1.345368132,2.5498268790000003,3.4320917019999997,3.834842751,3.61705571,2.9999963760000004,3.0847158130000003,3.623847862,0.062596968,2.16086604,-0.10569429397583008,-1.1449079513549805,-0.47747802734375,-0.49612897634506226,0.28313684463500977 -2835,2835,N173F,-0.065032233,-0.044671398,-0.018176517,-0.058276960999999995,-0.024432157000000003,0.018264583,-0.052821078,-0.077243388,0.082362744,0.024836834,-0.114179629,-0.008987913,-0.027365121000000003,0.00209299,-0.118646912,0.018915325,-0.067779638,1.138968955,2.6583521969999997,-5.21633231,-7.600942291,-5.173079926000001,-4.812976128,-4.361176155,-4.1334870530000005,-5.189178868,-2.519573181,-7.730494976043701,-7.3815531730651855,-6.480541229248047,-7.10929012298584,-6.280368804931641 -2836,2836,N173I,0.023717112999999998,-0.005189174,-0.022162865,0.014634442,-0.31411793600000004,0.072175004,0.048504119000000005,-0.0010698939999999998,-0.048154616,-0.05589482,0.045516472,-0.030282081000000002,-0.014043648,-0.003842791,0.033111674,-0.29894287199999997,-0.329292999,1.5646825480000002,2.074081493,-5.158388396,-4.04605407,-4.706553116,-6.16615654,-6.462567635,-4.410610619,-5.188377326,-0.532361682,-8.096054077148438,-9.159215927124023,-9.969513893127441,-8.05696964263916,-9.064842224121094 -2837,2837,N173H,-0.018152499,0.029554828,-0.005303441,-0.015475341,0.002965655,0.01376499,-0.033212343,-0.0030926540000000002,-0.016413853,0.104642955,-0.045533299000000006,0.0028223470000000002,-0.013429228,0.010117134,-0.041067815,0.011759904,-0.005828594,1.166459095,2.648404694,-2.9541436689999996,-3.857161118,-2.817829872,-2.5371143259999998,-2.549466133,-3.0091468960000003,-3.956380424,-1.7013822809999999,-4.983802795410156,-4.770786285400391,-4.969529151916504,-3.8365416526794434,-4.044682025909424 -2838,2838,N173K,-0.012951778999999998,-0.031149081000000002,0.008291035,0.008988504,-0.014792412,-0.023180697000000004,-0.005920991,-0.019982566,0.010473745999999999,-0.00499769,-0.057300471,-0.002366,0.01894807,0.019428551999999998,-0.001451544,0.008688904,-0.038273727,1.264115617,2.776666739,-1.143728734,-0.40531778700000004,-0.278602463,-0.999094185,-2.46672744,-1.568901794,-2.3649620209999997,0.400786939,-5.288082122802734,-6.815060615539551,-6.091640472412109,-4.062182426452637,-4.5424604415893555 -2839,2839,N173M,-0.030488914,-0.016288733,-0.000592062,-0.006250774000000001,-0.054697623,0.002449613,-0.016958651,-0.044019177,-0.030854841,-0.002291797,-0.030285667999999998,0.0035439559999999996,-0.00472808,-0.030949136000000002,0.018447588,-0.066137294,-0.043257950999999996,1.213159661,2.2732302030000002,-6.629217696,-6.079475112999999,-5.8601058429999995,-7.631908051,-7.460525597,-6.114073875,-5.477377975,-2.250224297,-8.31379508972168,-8.261499404907227,-7.651665687561035,-7.215060234069824,-7.762523174285889 -2840,2840,N173L,-0.015126918999999999,-0.009105936,-0.022944468,-0.018635164,-0.030604266,-0.016878739,-0.009211185,-0.021042652000000002,0.017450101000000003,0.018084547,-0.036296418,-0.047634787000000005,0.0017458520000000002,-0.02408399,-0.013186338,-0.037431812,-0.023776718999999998,1.20233237,2.401994425,-4.301497604,-3.627875008,-4.1051952819999995,-5.2760477219999995,-5.534057434,-2.964312576,-3.58166368,-0.28901689399999997,-6.836593151092529,-6.6199822425842285,-5.915567874908447,-6.270196437835693,-6.49519681930542 -2841,2841,N173Q,-0.031887827,-0.008382269,-0.007088817,0.0007295930000000001,0.023715873999999998,0.029596575,-0.043756562,-0.020019092,0.03804839,0.035858024,-0.052622561,0.010584621,-0.024762253999999997,-0.013481101,0.014940287,-0.01873685,0.066168597,1.207256321,2.5167904119999998,-3.6310231839999996,-4.1630152439999994,-2.365865685,-3.909438522,-4.804236595,-2.912559875,-4.385818965,-0.22830900899999998,-5.435474395751953,-6.73288106918335,-6.66689395904541,-4.513851165771484,-5.427592754364014 -2842,2842,N173P,-0.02212302,-0.001234391,0.009059293000000001,0.0027470109999999997,-1.7161871430000002,0.49544348299999996,-0.010301439,-0.0339446,-0.004613963,0.003117178,-0.005585959000000001,-0.048739033,0.06685761900000001,-0.012387493999999999,0.017881516,-1.497526418,-1.9348478669999998,0.66379259,1.319291736,-4.4959891569999995,-4.750328377,-5.165717453,-4.331642296,-5.2471920469999995,-2.985065613,-4.6554476639999995,0.552280031,-8.511789321899414,-11.418172836303711,-9.926590919494629,-8.421228408813477,-8.954208374023438 -2843,2843,N173S,0.01982762,0.011568057,0.023774447,0.019108757,-0.000747788,-0.01700364,-0.003428385,0.043083625,0.016498936999999998,0.017113987,0.0060221269999999995,-0.013227043,0.060775937,0.001522205,0.036695309,-0.043010846,0.041515271,1.414904449,2.54082215,-1.184478726,-1.098721489,-1.419968216,-1.6590315930000001,-0.610461227,-1.134211105,-2.921137481,-0.405690245,-5.005568981170654,-5.933370113372803,-5.836273193359375,-5.223308563232422,-4.798407077789307 -2844,2844,N173R,0.019599032,0.021942557,0.024035294,-0.015800575,-0.050087137000000004,-0.012407962,0.023468021000000002,0.015730043,-0.002347408,0.023770677999999996,0.020114436,-0.014398598,0.062469185999999996,-0.02023669,-0.01136446,-0.095554241,-0.004620033,1.206623067,2.244273076,-3.525812575,-3.74708847,-2.801318329,-3.694113075,-4.8580986710000005,-2.528444328,-3.807194379,0.23209979100000003,-5.6867547035217285,-5.620047569274902,-5.908775806427002,-3.960134983062744,-4.2368083000183105 -2845,2845,N173T,0.015469235,-0.006757010999999999,-0.010485862,-0.005613795,-0.027061775,-0.039670235,0.008124669000000001,0.022813801,0.017541461,0.018315236999999998,-0.031829258,-0.03524985,0.014278126,-0.039189443,0.027961853999999998,-0.079821878,0.025698328,1.276815348,2.2728484669999998,-2.079378719,-0.92025946,-2.566160385,-2.666741058,-2.447819695,-1.795912994,-3.3247067930000003,-0.555265434,-6.037542819976807,-6.9367289543151855,-6.585333347320557,-6.170069694519043,-6.261866569519043 -2846,2846,N173W,0.026021317000000002,0.032000252,0.020948564,0.022435255,-0.004127451,-0.015243713999999998,0.032901101,0.019141533,-0.02724949,0.038733973,0.025266531000000002,0.015829975,0.026067153,-0.009690456,0.054560965,-0.021424036,0.013169133999999999,1.2387622759999999,2.562574386,-4.591917596,-5.531064194,-4.987632431000001,-3.976604988,-5.3799477079999996,-3.0843386610000003,-4.454155663,-0.9880047270000001,-9.224884033203125,-7.18902063369751,-8.12755012512207,-7.8397698402404785,-6.5919108390808105 -2847,2847,N173V,-0.008661536,0.004203941,0.022232166,-0.005998165,-0.25577747100000003,0.026388557000000003,-0.018732144,0.0014090729999999998,-0.014895101000000001,-0.005189509,0.013597391,-0.027048137000000003,0.071512468,-0.036358243,0.024361913,-0.26460916100000004,-0.24694578,1.5305716569999999,2.001357715,-3.915617957,-1.373306343,-3.52046376,-4.880979568,-5.799297646,-4.004042465,-3.9730262960000005,0.22084219300000002,-6.911449432373047,-8.607613563537598,-8.937647819519043,-7.366211891174316,-7.501110553741455 -2848,2848,N173Y,-0.079363867,0.025983352999999997,0.022069182000000003,-0.002515225,0.017112284,0.015775837,-0.022957961000000002,-0.135769773,0.014858208999999999,0.065495825,-0.01352912,0.041286847,0.0028515159999999997,0.028284642999999998,-0.033315092000000004,-0.010042843000000001,0.04426741,1.153400526,2.75274485,-4.031157385,-5.249492523,-4.06450106,-3.6599555510000004,-3.4281777730000003,-3.753660019,-4.713525265,-1.538049508,-7.860813617706299,-7.085165977478027,-6.631193161010742,-7.084792137145996,-6.18734884262085 -2849,2849,D174A,-0.052629167000000004,0.003324744,-0.019212198,-0.75887084,-2.121400628,0.007686256,0.018223813000000002,-0.12348214699999999,-0.058473328,-0.00196796,0.008617447,-0.045184178,0.006759782,-0.507834937,-1.009906742,-2.097991022,-2.144810234,1.6382496469999999,1.353995745,-10.72180954,-11.98618529,-11.0874538,-10.10832262,-9.611200455,-10.81588554,-6.749222704,-2.044681056,-11.547926902770996,-11.279059410095215,-10.527753829956055,-7.352358818054199,-13.294175148010254 -2850,2850,D174C,-0.14487539,0.031707962,-0.048474830999999996,-0.012351426,-1.4579015780000002,0.024806731000000002,-0.126147839,-0.16360294,-0.038815783,0.091345199,-0.027929276,-0.059874285,-0.037075376,-0.00651857,-0.018184281,-1.621256896,-1.294546259,0.624152881,1.311173159,-15.31797137,-16.90184961,-16.13804378,-13.63742892,-14.49939695,-15.41313757,-8.898604022,-3.6533692460000005,-13.848037719726562,-15.706864356994629,-13.431015014648438,-12.189046859741211,-17.3844051361084 -2851,2851,D174E,-0.042995964000000005,0.05843266,-0.017634674,-0.006814221,-0.7127737590000001,0.109284701,-0.00042987900000000004,-0.085562048,-0.032331413999999996,0.083670847,0.033194472999999995,-0.027934529,-0.007334818000000001,-0.010541958999999998,-0.0030864829999999997,-0.575847137,-0.8497003809999999,0.860021519,1.458078294,-6.850690947,-8.231850166000001,-8.379272308,-5.904459877000001,-5.553889221,-6.1839831620000005,-5.93359849,-1.817969274,-8.778761863708496,-9.836679458618164,-6.1158576011657715,-7.161551475524902,-10.613119125366211 -2852,2852,D174G,-0.05122339,0.028650339,0.0021016439999999997,-0.190435789,-1.960745279,0.008787521,0.0014168579999999998,-0.103863637,-0.04753417099999999,0.037825601,0.019475077,-0.009307786,0.013511074,-0.11285525800000001,-0.268016319,-1.6843353680000002,-2.23715519,0.9283353940000001,1.32552305,-10.734598599999998,-11.72497608,-13.26781647,-11.3823937,-8.288051575,-9.009755188,-5.957762258,-0.788055044,-12.347391128540039,-11.715996742248535,-10.617265701293945,-8.991737365722656,-14.311057090759277 -2853,2853,D174F,-0.121080189,0.002685033,-0.510628104,-1.781082166,-2.8999826619999998,0.005956688000000001,-0.09031271699999999,-0.151847661,-0.070098088,0.059261540999999994,-0.053891475,-0.27968969,-0.741566518,-1.6885491259999998,-1.873615205,-2.574595567,-3.225369756,1.3232390170000001,0.749759396,-17.31291887,-18.41995615,-20.33129092,-14.99844891,-13.599502300000001,-19.21539608,-8.260778515,-3.916737587,-14.423564910888672,-15.274887084960938,-12.430400848388672,-12.243824005126953,-16.015653610229492 -2854,2854,D174I,-0.060031985999999996,0.04373365,-0.042478710999999995,-1.767508024,-2.5516905569999997,0.076786745,0.023200632000000002,-0.14326460300000002,-0.057860583,0.0431468,0.044320499000000006,-0.067198841,-0.01775858,-1.51627307,-2.018742978,-2.377495927,-2.725885187,0.7886836979999999,0.7087084570000001,-14.82132415,-16.29657623,-17.45395241,-13.54354298,-12.28734844,-14.52520071,-8.602615199999999,-4.962971945,-12.158635139465332,-13.832780838012695,-11.99675464630127,-10.207968711853027,-15.618196487426758 -2855,2855,D174H,-0.008465674,0.035613992000000004,0.029013143999999998,-1.4936656209999999,-2.623160767,0.025922514,-0.014194878000000001,-0.00273647,-0.059021507,0.029850462,0.041377521,-0.024571614,0.082597901,-1.205178922,-1.78215232,-2.334263412,-2.912058122,1.024948377,0.7740566059999999,-13.42042128,-15.116016199999999,-14.30366535,-13.77900986,-10.4713991,-13.43201588,-8.940356751,-4.78260309,-11.350715637207031,-11.779173851013184,-9.648427963256836,-9.12142276763916,-11.563102722167969 -2856,2856,D174K,-0.11881668,0.042919612999999995,-0.393902232,-1.886997904,-2.962412655,0.048693848,-0.040677891,-0.196955468,-0.081535836,0.07299053,0.012848695,-0.198611228,-0.5891932360000001,-1.528753655,-2.245242153,-2.389976512,-3.534848797,1.204553149,0.756009348,-12.08782319,-12.85727001,-14.922868300000001,-12.20642,-10.30637704,-10.14618062,-7.740219294,-3.7693246069999997,-12.700124740600586,-13.468619346618652,-11.781411170959473,-9.861444473266602,-15.079469680786133 -2857,2857,D174M,-0.10060737,0.009207077,-0.023731243,-1.3248412509999998,-2.8421316689999996,-0.008027923000000001,-0.052720333,-0.148494407,-0.021529929,0.016310466000000003,0.002103688,-0.050189852,0.002727367,-0.8716322740000001,-1.7780502280000001,-2.451796216,-3.232467122,1.017395755,0.836546245,-14.63039694,-14.82352807,-17.30967104,-13.18460075,-11.62433072,-16.20985413,-8.139779653,-4.486792331,-13.995959281921387,-15.152996063232422,-12.785701751708984,-11.61623764038086,-16.372804641723633 -2858,2858,D174L,-0.06593769599999999,0.034121741000000004,-0.002635099,-1.798651445,-2.590402136,0.023881523999999998,-0.030506029,-0.101369363,-0.054496544,0.062456752000000004,0.005786729,0.013274433,-0.018544631000000002,-1.494513623,-2.102789266,-2.322568117,-2.858236155,-0.020622953,0.683024565,-13.40808023,-14.27438631,-17.23506212,-12.21390413,-8.933121086,-14.38392751,-7.79682329,-3.317974661,-12.87346076965332,-14.835500717163086,-11.866968154907227,-10.63685417175293,-15.35254955291748 -2859,2859,D174N,-0.12302409,0.006339142,-0.038943864,-0.054175147,-2.324862848,0.043555288,-0.026408582000000003,-0.21963959800000002,-0.101102369,0.036782956,-0.024104672,-0.03869449,-0.039193238,-0.053868313,-0.054481981,-1.911499819,-2.738225877,0.8857948309999999,1.307908979,-8.112277916,-9.358982574,-7.574041458,-7.766176125,-8.592784568999999,-7.269404853999999,-6.23158537,-3.1152999930000003,-8.412528991699219,-8.508420944213867,-7.964029788970947,-7.084015846252441,-9.636951446533203 -2860,2860,D174Q,0.001966151,0.053777371,0.012006858,-0.011301994,-2.490967543,0.034189321,-0.014093236,0.018025538,-0.077660242,0.08744518400000001,0.020109557,0.007728953,0.016284763,0.005846175,-0.028450162,-1.7576675990000001,-3.2242674860000005,0.473835437,1.30135375,-12.04189703,-15.05711369,-12.87870181,-11.01854622,-10.33882002,-10.91630344,-6.812272248999999,-1.7762256090000001,-11.839828491210938,-12.982254981994629,-10.068239212036133,-9.138152122497559,-13.585734367370605 -2861,2861,D174P,-0.03251293,0.024434311,-1.108504614,-2.094969647,-3.314416907,0.060837423,0.031681674,-0.09670753300000001,-0.060850844,0.024807843,0.024060777999999998,-1.0025577970000001,-1.2144514309999999,-2.098431038,-2.091508256,-2.770597659,-3.858236155,0.692873078,0.11777025199999999,-13.79912807,-16.70872829,-14.41170055,-13.1364435,-11.00756654,-13.73120151,-7.3574719129999995,-3.59882789,-14.476628303527832,-14.920774459838867,-11.035059928894043,-12.225351333618164,-18.354612350463867 -2862,2862,D174S,-0.08567733300000001,0.035044848999999996,-0.015640083,0.00855648,-1.527444944,0.104100545,-0.045088948,-0.126265717,-0.042696326,0.045241312,0.024848385,-0.012585198999999998,-0.018694967,0.015323951,0.001789009,-1.558584613,-1.496305274,0.6997556159999999,1.3183804909999999,-11.29878411,-13.99638942,-11.124955300000002,-10.46778622,-11.21910447,-9.685685127000001,-6.383975679,-2.304830747,-10.71822738647461,-12.126571655273438,-10.021031379699707,-8.63656234741211,-13.997007369995117 -2863,2863,D174R,-0.028739273,0.030905215,-0.673220278,-1.900896381,-3.00426622,0.010353586,0.01353992,-0.071018465,-0.048604733,0.032033419,0.02977701,-0.42173279,-0.924707765,-1.802810526,-1.998982235,-2.413381076,-3.595151364,1.61656737,0.789696553,-12.95140664,-14.89354681,-15.53130252,-14.29268494,-9.473947357,-10.56555155,-7.097927007000001,-2.39717509,-13.683815956115723,-13.901172637939453,-12.562602996826172,-9.5503511428833,-16.300518035888672 -2864,2864,D174T,-0.085681779,0.023085966,0.006709983,-0.602217559,-2.4560801740000002,0.040680047000000004,-0.013226696999999999,-0.15813686,-0.044922271,0.049807909000000004,-0.0036359779999999998,-0.029384902999999997,0.042804869,-0.284968071,-0.919467046,-1.8750219559999999,-3.037138391,1.351548306,1.346736471,-11.61514034,-13.79932217,-13.16772493,-10.32089631,-9.042235359,-11.745522900000001,-6.516578542,-2.429377386,-11.88447380065918,-12.049104690551758,-10.42077350616455,-9.330063819885254,-15.162528038024902 -2865,2865,D174W,-0.065688432,0.003438618,-0.829227068,-2.085911512,-3.101784767,0.013990912,-0.034423651,-0.09695321300000001,0.004511703,-0.0038941040000000002,0.010771339,-0.527036315,-1.1314178209999999,-1.8555849999999998,-2.316238024,-2.507548234,-3.696021299,1.703817929,0.795774579,-16.33919035,-18.16587011,-17.91834765,-15.34762374,-13.49255187,-16.77155839,-9.16027713,-5.570763137,-16.1529598236084,-16.89410972595215,-15.210776329040527,-14.533563613891602,-18.22201919555664 -2866,2866,D174V,-0.10716180800000001,0.002036564,-0.036421864,-1.473654375,-2.7174936080000003,0.019101382,-0.041259022,-0.173064594,-0.053902593,0.014525455,-0.010452328,-0.026921307000000002,-0.04592242,-1.007927867,-1.939380883,-2.31994304,-3.115044175,0.823624515,0.7717848690000001,-14.06362061,-15.68441897,-16.11815984,-12.93904907,-11.38807688,-14.18839827,-8.271656587,-4.240862203,-11.645462036132812,-12.516618728637695,-11.480669975280762,-8.88231372833252,-13.784390449523926 -2867,2867,D174Y,-0.109499537,-0.005627213000000001,-0.296041971,-2.311744967,-2.7255582310000004,0.028563421000000002,-0.028472921,-0.190526152,-0.050086654,-0.003662603,-0.007591822,-0.152966273,-0.43911766799999996,-1.933356197,-2.6901337360000004,-2.284289437,-3.166827024,1.122447296,0.686400881,-16.93467668,-18.80760307,-20.257714399999998,-14.70762085,-13.47006979,-17.43037528,-8.835744072,-2.590810884,-13.363876342773438,-13.617730140686035,-11.902861595153809,-11.640554428100586,-13.986489295959473 -2868,2868,E175A,-0.023573853,-0.016242182,0.020863976,0.025225471,-0.050278435999999996,0.041145537,-0.077638868,0.030491162999999998,0.043845836,0.005261324,-0.037745688,-0.005516729000000001,0.047244681,0.02871346,0.021737481,-0.041828979,-0.058727892000000004,1.3125776759999999,2.553003902,-2.408082179,-2.17261647,-2.252398941,-2.175702911,-3.133446915,-2.306245659,-3.2611604339999998,-1.191461162,-5.460811614990234,-4.933687210083008,-5.347172260284424,-3.8871071338653564,-5.093625068664551 -2869,2869,E175C,0.013717798,-0.014984208,-0.030447693999999997,-0.019242896000000002,-0.115690451,0.075216558,-0.00033293699999999995,0.027768532999999998,0.061553884,0.0009541780000000001,-0.030922593999999998,-0.058915536,-0.0019798520000000003,0.00798784,-0.046473630999999994,-0.070737669,-0.160643232,1.24745667,2.3568389830000003,-7.926379904,-7.830895592,-7.026179115,-8.544173714,-8.847645424,-7.383005676,-7.8563292229999995,-4.092048968,-10.807159423828125,-13.215225219726562,-9.88985538482666,-10.04336929321289,-13.293378829956055 -2870,2870,E175D,-0.076617398,-2.6899999999999997e-05,-0.016089655,-0.030750039,-0.10061042199999999,0.07244124099999999,-0.120969807,-0.032264988,0.051016942,0.031624782000000004,-0.031678554,-0.0027454999999999997,-0.029433809,-0.006558662,-0.05494141599999999,-0.005168624,-0.19605221899999997,1.245981066,2.677609437,-2.983296437,-2.6456414109999997,-2.786388657,-3.1558368910000003,-3.2451698610000004,-3.0834453660000003,-4.784790538999999,-1.137091138,-6.1846489906311035,-5.965031147003174,-5.53333854675293,-4.809117317199707,-6.441241264343262 -2871,2871,E175G,-0.06587765,-0.050816919,-0.023361972999999998,-0.025041321000000002,-0.280954368,0.050455604,-0.098050026,-0.033705274,0.037089463999999996,-0.0029146090000000003,-0.098719228,-0.0109958,-0.035728146,-0.001636574,-0.048446067,-0.22394856100000002,-0.337960175,1.201525363,1.93779228,-5.573690318,-6.443444167999999,-4.412306511000001,-6.338917885,-6.641439957,-4.032343071000001,-6.13639156,0.270719887,-8.56776237487793,-8.627106666564941,-7.441790580749512,-7.3747429847717285,-9.274713516235352 -2872,2872,E175F,-0.045212979,-0.040929692000000004,-0.010700589,-0.021737995,-0.14040323300000002,0.028848342000000003,-0.12060600199999999,0.030180045,0.019270782,-0.005088418,-0.076770966,-0.02277923,0.001378052,-0.041955785,-0.001520204,-0.139327851,-0.141478614,1.488534738,2.279591948,-7.36818071,-7.689630188,-5.958109451,-7.569274269,-9.008226517,-6.615663124,-6.479535997,-0.808225119,-8.708624839782715,-9.01887321472168,-5.89738655090332,-8.698078155517578,-9.177188873291016 -2873,2873,E175I,-0.0012650460000000001,-0.041455608,-0.036920166000000004,0.010638908,-0.070853735,0.025260346,-0.027684461,0.025154369,0.038113526,0.011070348,-0.093981563,0.025107018999999998,-0.09894735,0.062070405999999995,-0.04079259,0.018651768,-0.160359237,1.076833718,2.62284945,-3.226594325,-3.9229702000000004,-3.1915204239999997,-3.279470711,-3.5696924969999997,-2.169317795,-4.805841631,-0.46729936299999997,-5.262180328369141,-6.3169636726379395,-3.1738390922546387,-5.313935279846191,-5.145316123962402 -2874,2874,E175H,-0.106882981,0.016259186999999998,-0.030562039,-0.0009547389999999999,-0.07025231400000001,0.037388245,-0.134146913,-0.079619049,0.041094934,0.05895549,-0.026437116,0.031693981,-0.09281805800000001,0.047751959000000004,-0.049661435999999996,0.013262804,-0.15376743199999998,1.21664648,2.720926035,-7.860020764,-7.389723061000001,-6.588069534,-8.686639808999999,-9.069827164,-7.565844254,-6.98197814,-1.601440502,-7.857861042022705,-8.133543968200684,-6.874965190887451,-7.0708770751953125,-8.062640190124512 -2875,2875,E175K,-0.050887752,-0.010827625,0.008479525,-0.0025658729999999998,-0.094820258,0.040425428,-0.060680845,-0.041094659,0.05379899900000001,0.046524259000000005,-0.068179509,0.04163954,-0.02468049,0.051135585,-0.05626733,-0.049495742,-0.140144773,1.344604634,2.553957834,-2.571526772,-2.526330353,-2.510010086,-2.58175396,-2.477536705,-2.7620027539999996,-3.988821562,-0.405303067,-5.542437553405762,-6.022680282592773,-5.270524024963379,-5.019754409790039,-4.021783828735352 -2876,2876,E175M,0.005580649,0.02554158,0.006446594,-0.0018265710000000001,-0.065348191,0.0500999,-0.017150891,0.028312188,0.048871498,0.07760550599999999,-0.026522346000000002,0.07213818799999999,-0.059245000000000006,0.023951855,-0.027604997000000003,0.019600532,-0.150296913,1.135845715,2.60945077,-4.705581284,-5.129372704,-4.95989579,-4.1844712369999995,-4.863535187,-4.3906315000000005,-5.949827238999999,-2.1633444230000003,-7.2106523513793945,-7.44033145904541,-6.326898574829102,-6.497607707977295,-6.91403341293335 -2877,2877,E175L,-0.042696057999999995,-0.054942569000000004,-0.017258676,-0.020633989,-0.077029978,0.023793559,-0.065295929,-0.020096186000000002,0.053199697000000004,-0.016991427,-0.09289371099999999,0.027417737,-0.061935089000000006,0.0017688720000000001,-0.043036849,-0.027458191,-0.126601765,1.276755325,2.5206573519999997,-2.341291339,-2.780376762,-2.828326935,-1.539412964,-2.882130959,-1.676209076,-4.031069281000001,0.09268606900000001,-5.642145156860352,-5.563115119934082,-4.6325788497924805,-5.0138044357299805,-4.280421257019043 -2878,2878,E175N,-0.031020645,-0.010699658,-0.036052543,-0.020251115,-0.118612428,0.006077944,-0.063020559,0.00097927,0.019345913,0.019697643,-0.041096959,-0.044050646,-0.028054439,-0.014590758,-0.025911472,-0.11465836,-0.122566496,1.4713195980000002,2.3419753919999997,-5.386352327999999,-4.9748358,-5.178721466,-5.810367546,-5.944981353999999,-5.022855476,-5.529574469,-1.5174738630000002,-7.796372890472412,-7.839460372924805,-7.111453533172607,-5.9362473487854,-7.257820129394531 -2879,2879,E175Q,-0.032596096,-0.048933727,-0.027570451,-0.03616869,-0.076423817,-0.019463694,-0.055277954000000004,-0.009914238,0.04569701,-0.0044695970000000005,-0.093397856,-0.028625968999999998,-0.026514932999999997,-0.007586883000000001,-0.06475049599999999,-0.011139013,-0.141708621,1.193999535,2.453429491,-3.777950479,-3.383546555,-4.148035339,-3.91202449,-3.9695091319999998,-3.476636879,-4.920014093,-1.633321715,-5.739552021026611,-6.119258880615234,-5.169353485107422,-4.573184967041016,-5.321169376373291 -2880,2880,E175P,-0.027726449,-0.023185427,-0.017261061,-0.005796712,-0.04213872,0.005935785,-0.067434976,0.011982079,0.03433395,0.013714965,-0.060085819000000006,-0.005608007,-0.028914113999999998,0.02441245,-0.036005873,0.014872564,-0.099150004,1.207911703,2.739397172,-0.709166814,-0.5467361070000001,0.091913986,-0.34905010200000003,-3.387084854,0.645123009,-2.668306264,0.88450424,-3.4370627403259277,-2.6694726943969727,-3.205775499343872,-2.1552276611328125,-3.6684343814849854 -2881,2881,E175S,-0.029040106,-0.018085041,-0.011261408,-0.007345385,-0.08198592,0.040974413,-0.063455861,0.005375649000000001,0.031119587999999997,0.014804102,-0.050974184000000006,0.026724381000000002,-0.04924719599999999,0.028694716000000002,-0.043385485,-0.01784204,-0.146129799,1.1861051759999999,2.606534576,-4.650903201,-5.249678299,-4.200985237,-4.988620514,-4.91926683,-3.895965126,-6.288125755,-1.904633836,-5.85669469833374,-6.648653507232666,-5.784311294555664,-5.5330939292907715,-6.426429271697998 -2882,2882,E175R,-0.003664968,-0.025145623,-0.020167833,-0.01518402,-0.167412478,0.024712261,-0.039506295,0.032176359,0.017854448999999998,0.013420989,-0.063712235,-0.017100436,-0.02323523,0.007041761999999999,-0.037409802,-0.12187449300000001,-0.212950463,1.51618479,2.407883191,-5.043027803,-4.702225845,-4.693409698,-5.37234581,-5.750666138,-4.696491524,-5.668445932000001,0.159446341,-6.406490325927734,-7.868311882019043,-5.903020858764648,-5.899492263793945,-6.272078037261963 -2883,2883,E175T,-0.049302415,-0.064397945,-0.033498009,-0.020719706,-0.106713349,0.043368414,-0.11239906699999999,0.013794236999999999,0.057213192,-0.031396573,-0.097399316,-0.013700644,-0.053295374000000006,0.01344031,-0.054879722,-0.033051302000000005,-0.18037539600000002,1.537094526,2.782064661,-4.250708008999999,-4.573365196,-3.996172112,-4.150927811,-5.47210939,-3.060965538,-5.302403676,-0.658955582,-5.674813270568848,-6.615698337554932,-5.124011993408203,-4.852886199951172,-4.309385776519775 -2884,2884,E175W,-0.028465358,-0.027556099,-0.017018591,0.010367648,-0.094118681,0.02304429,-0.07840261,0.021471895,0.075198544,0.014235245,-0.069347442,0.00784658,-0.041883762000000005,0.033199071000000004,-0.012463775,-0.031959226,-0.156278135,1.234983777,2.523943991,-9.056844386,-9.010469367999999,-7.737675606,-9.746597748,-10.3212368,-8.468242409,-7.411446278,-3.4003549439999996,-9.739442825317383,-11.03034496307373,-9.444604873657227,-9.976409912109375,-11.284162521362305 -2885,2885,E175V,-0.013857551999999999,-0.051942445999999996,-0.02632217,-0.01390373,-0.076902895,0.042646736,-0.041868388,0.014153283999999999,0.073395173,-0.032441187999999996,-0.071443703,-0.032431154,-0.020213185,-0.002121189,-0.025686271,-0.034044138,-0.119761652,1.265448124,2.439184837,-1.456077205,-0.9110008009999999,-1.56192775,-1.302009056,-2.2327381969999998,-1.27271022,-3.12519391,-0.360532869,-5.088042736053467,-5.559169769287109,-3.878722667694092,-4.553711891174316,-4.551165580749512 -2886,2886,E175Y,-0.129098959,-0.057639795,-0.049609427000000005,-0.020388088999999998,-0.10930506599999999,0.066133737,-0.138017212,-0.120180706,0.010515573,0.005197638,-0.120477228,0.011034663,-0.110253517,0.033250793,-0.07402697,-0.0005698869999999999,-0.218040244,1.130303773,2.484304809,-8.087906705,-8.679746597000001,-6.101220177,-9.16758889,-8.224896843,-8.266081017000001,-6.2237845,-0.096125799,-8.803851127624512,-9.484375953674316,-6.502921104431152,-8.543754577636719,-9.25067138671875 -2887,2887,R176A,-0.071857298,-0.026350661,-0.060884604,-0.047761581,-0.8559719859999999,0.18060963600000002,-0.076465699,-0.067248896,0.044583799,-0.026169121,-0.0265322,-0.053905919000000004,-0.067863288,-0.041319787000000004,-0.054203375,-0.746472037,-0.9654719340000001,1.054332027,1.480085921,-11.19985853,-11.74871239,-11.42112824,-11.19811203,-9.601659721,-12.02968026,-6.957355057000001,-2.076338752,-13.31701374053955,-14.659245491027832,-11.778682708740234,-11.073657035827637,-12.120296478271484 -2888,2888,R176C,0.081896215,0.099546566,0.104517165,0.08105512200000001,-0.5922636139999999,0.067848929,0.06304145,0.10075098,0.093343891,0.11008722300000001,0.08900590800000001,0.09079726099999999,0.118237069,0.09094362800000001,0.071166615,-0.476471638,-0.70805559,1.211113039,1.684792244,-12.6104972,-12.71686913,-12.58791218,-13.00278628,-11.51872523,-13.2261932,-8.426318326,-5.57589878,-13.129120826721191,-16.560413360595703,-11.104681015014648,-10.168740272521973,-10.872476577758789 -2889,2889,R176E,-0.11772596699999999,0.002897525,0.014373545,-0.055572548,-1.282004161,0.186238877,-0.118580635,-0.116871299,0.016458605,0.020077149,-0.014282099999999999,-0.029786429,0.058533519000000006,-0.073014821,-0.038130274,-1.36727279,-1.196735532,0.887806359,1.345681966,-11.72385191,-13.81853106,-11.33221478,-11.10415488,-10.78763503,-11.576723800000002,-6.969477724,-1.6314722080000001,-15.359346389770508,-15.712484359741211,-13.645500183105469,-11.563648223876953,-12.386811256408691 -2890,2890,R176D,0.043977391,0.046168442000000004,-0.042369194000000006,-0.094755875,-1.773480238,0.079257619,0.065327048,0.022627732999999997,-0.00680394,0.046136279,0.046200605,-0.065179778,-0.019558608999999998,-0.042928201,-0.146583548,-2.05463958,-1.492320895,0.8205529640000001,1.297180087,-13.03739702,-15.60400839,-13.91822433,-12.09697907,-11.39557787,-12.17219541,-6.152511783,-1.796460224,-15.627128601074219,-15.35015869140625,-13.870088577270508,-13.377619743347168,-14.217012405395508 -2891,2891,R176G,-0.063106391,-0.022211584,-0.048380919,-0.019576468,-1.789170972,0.063134692,-0.06757661400000001,-0.058636167,0.019344687,0.001609837,-0.046033005,-0.055206884000000005,-0.041554953,-0.020162786000000002,-0.018990148999999998,-1.677332825,-1.901009119,0.466340995,1.303002185,-12.25653717,-12.49552354,-12.97960055,-12.48998045,-11.01876628,-12.29881505,-7.704117196,-3.464066663,-13.740914344787598,-15.792333602905273,-11.092361450195312,-12.144611358642578,-13.181781768798828 -2892,2892,R176F,-0.078119647,-0.012283503999999999,-0.037038031,-0.074999277,-1.1687866000000002,0.111451446,-0.025873397000000003,-0.13036589699999998,0.008647051,0.069672318,-0.094239326,0.025771687,-0.099847749,-0.009968683,-0.14002987,-0.7718025890000001,-1.565770611,0.829547367,1.4113128519999998,-14.59949924,-15.35678038,-14.62412141,-13.87090638,-11.5357986,-17.60988942,-7.86649232,-4.433807142,-15.172035217285156,-16.08805274963379,-12.961136817932129,-13.010516166687012,-12.520463943481445 -2893,2893,R176I,-0.06486821799999999,-0.025724652,0.024929708,-0.134505508,-2.562807203,0.053181804000000006,-0.027513064,-0.102223371,-0.060774358,-0.099329099,0.047879795,-0.050975728,0.100835144,-0.10374943800000001,-0.16526157800000002,-2.291552076,-2.8340623289999995,0.969561498,1.277405341,-14.39259583,-14.72611429,-15.62384715,-15.10842486,-9.918622168999999,-16.58597068,-8.268505776,-3.4805710810000003,-14.760311126708984,-14.353044509887695,-12.43558120727539,-10.226011276245117,-11.172439575195312 -2894,2894,R176H,-0.065217183,-0.007553496999999999,-0.0018129620000000002,-0.049010597,-0.693165748,0.084917602,-0.054914179,-0.075520186,0.020895689,0.007942404,-0.023049398,-0.045968682000000004,0.042342758,-0.061493344000000005,-0.036527849,-0.517046005,-0.86928549,1.759346656,2.020303871,-7.28690563,-8.586422691000001,-7.138146606,-6.891790604,-7.280798775,-6.537369476,-6.114816599,-3.685320462,-10.952264785766602,-10.546361923217773,-9.801309585571289,-8.505239486694336,-8.145950317382812 -2895,2895,R176K,-0.060087167999999996,-0.056300399,-0.039740914,-0.092763737,-0.250014334,-0.070662839,-0.070374157,-0.04980017900000001,0.13556902699999998,-0.025150391,-0.087450406,0.046887730999999995,-0.12636955800000002,-0.07186029299999999,-0.11366718,-0.158013168,-0.34201550000000003,1.4529990019999999,2.223525207,-8.478686736,-10.51901148,-8.710116287,-8.352342339,-7.075342804,-7.736620766000001,-6.029048124,-2.829217665,-11.716937065124512,-11.714237213134766,-10.149415969848633,-8.566761016845703,-8.837911605834961 -2896,2896,R176M,-0.07452096,-0.04296967,-0.050676895,-0.016271566,-0.688151548,0.200877917,-0.08569246,-0.063349459,0.209169722,-0.074523659,-0.01141568,-0.06338978,-0.037964009,-0.033254371,0.0007112389999999999,-0.392349386,-0.98395371,1.243076001,1.748497349,-13.289180300000002,-13.66903976,-13.46973713,-14.53101938,-9.737071251,-15.039034,-7.5920538539999995,-4.278713403,-14.765514373779297,-15.39486312866211,-12.764348030090332,-11.380654335021973,-10.34625244140625 -2897,2897,R176L,-0.096856507,-0.033694548,-0.020470089,-0.052466595,-0.760679487,0.137558155,-0.088995025,-0.10471798800000001,-0.013131368000000001,0.0221601,-0.089549196,-0.024171613999999998,-0.016768564,-0.018793781000000002,-0.086139409,-0.60958179,-0.9117771840000001,0.896348162,1.4670576880000001,-9.890960172,-9.530928482,-10.01421451,-12.15523392,-5.55966449,-12.19475946,-6.11180845,-2.045677242,-13.358592987060547,-13.760025024414062,-10.664972305297852,-9.149284362792969,-9.26192855834961 -2898,2898,R176N,-0.002351286,-0.006509551,-0.011815973,-0.006562266999999999,-0.755379623,0.120316101,0.049573357,-0.054275929,-0.029175372,0.03071047,-0.043729572,0.02260164,-0.04623358599999999,0.008706603,-0.021831136,-0.553123887,-0.9576353590000001,0.708140476,1.4286856030000001,-12.2575676,-14.58612895,-13.07768082,-11.68727044,-11.53003071,-10.4067271,-7.332763012999999,-2.2220546409999997,-14.020999908447266,-13.32017707824707,-11.972298622131348,-11.400208473205566,-10.6703462600708 -2899,2899,R176Q,0.002410165,-0.033840691,-0.037146003999999996,-0.028296515,-0.097072605,0.034658844,0.006677075,-0.001856745,0.01608072,-0.04228859099999999,-0.02539279,-0.076152514,0.0018605070000000002,-0.011040685,-0.045552345,-0.16658389699999998,-0.027561312,1.4807089519999999,2.244304579,-6.99205938,-7.715565514,-6.932929855,-6.685892288,-6.189306548999999,-7.436602692,-5.47673551,-2.497989822,-12.423367500305176,-13.119087219238281,-11.178646087646484,-8.370223045349121,-7.150890827178955 -2900,2900,R176P,-0.051587142,-0.015072617,-0.008273108000000001,-1.7197842719999998,-2.9011935230000003,0.00449049,-0.037396287,-0.065777997,-0.002902398,3.64e-05,-0.030181633,-0.023411242999999998,0.006865026999999999,-1.5075487159999998,-1.932019827,-2.5678654290000003,-3.234521617,0.6871522109999999,0.7034870540000001,-12.50421708,-12.31322327,-11.40193111,-14.58711528,-10.66496048,-13.55385524,-7.872245032,-3.6067301360000004,-15.574483871459961,-17.2757625579834,-13.872842788696289,-12.983116149902344,-14.35032844543457 -2901,2901,R176S,-0.02843112,-0.004567522,-0.025602594,0.001998315,-0.660139414,0.291414187,-0.039150459,-0.01771178,-0.041477825,-0.007555475999999999,-0.001579567,-0.02482301,-0.026382177000000003,0.005701093000000001,-0.001704464,-0.493077651,-0.8272011770000001,0.8587854359999999,1.494811167,-11.41301496,-11.63341774,-10.81336767,-11.84196874,-10.43382599,-12.34249464,-6.11452491,-2.666307065,-12.047697067260742,-14.636186599731445,-11.351592063903809,-9.964977264404297,-11.362890243530273 -2902,2902,R176T,-0.042435185,-0.019027479,-0.014098273,-0.060936251,-2.210755806,0.062656245,-0.031759347,-0.053111023,0.012096114,-0.006081823,-0.031973135,-0.052582805,0.02438626,-0.002329576,-0.119542925,-1.665677082,-2.755834529,0.578072086,1.308581815,-13.63722695,-12.65398789,-14.43475518,-13.76278414,-12.76957018,-14.56503735,-6.19954912,-1.2771537370000001,-12.628055572509766,-13.130806922912598,-11.182793617248535,-9.363506317138672,-10.523723602294922 -2903,2903,R176W,-0.10178399199999999,-0.025738565,-0.034434598,-0.06049273,-1.4253905690000002,0.007918399999999999,-0.10989349300000001,-0.093674491,0.021248077,0.013205257,-0.064682386,0.00052512,-0.069394315,-0.021232731,-0.09975272800000001,-1.414016194,-1.436764943,0.681291911,1.322644984,-13.12296577,-12.65916666,-14.40130931,-13.46072641,-10.74812091,-14.34550555,-7.871908125,-2.7454843139999996,-13.725502014160156,-15.993548393249512,-14.366930961608887,-12.680583953857422,-11.86182689666748 -2904,2904,R176V,-0.08885187300000001,0.005675449,-0.02162835,-0.001205772,-2.112091666,0.085513641,-0.055084439000000006,-0.122619307,0.037619699,0.072465218,-0.061114321,0.038838839,-0.08209553900000001,0.035709838,-0.038121382,-1.5593728359999999,-2.664810495,0.719369325,1.317873495,-13.49466811,-13.84304639,-15.32251915,-14.51787228,-9.483109909,-14.30679281,-7.3998677289999994,-3.264252615,-14.792680740356445,-14.219675064086914,-12.579068183898926,-10.292478561401367,-11.779983520507812 -2905,2905,R176Y,-0.025176067000000003,-0.021198977,-0.035533687,-0.048669883,-1.119486404,0.054994415,-0.030569507000000003,-0.019782627,0.005507186,0.045658139,-0.08805609199999999,-0.060970892,-0.010096481,-0.005130082,-0.092209684,-0.9082931409999999,-1.330679666,0.8668357320000001,1.391633495,-13.44342972,-14.99558603,-14.22862951,-12.56653098,-12.27742448,-13.14897758,-7.867198952000001,-3.7373933010000004,-14.215879440307617,-14.054332733154297,-12.857295989990234,-12.521163940429688,-11.46805191040039 -2906,2906,D177A,-0.016120823,-0.24444147,-1.853532287,-2.13614782,-2.777766007,-0.042933255999999996,-0.0056260369999999995,-0.026615608,-0.007144463,-0.14413211199999998,-0.34475082700000004,-1.820313279,-1.886751295,-1.874339039,-2.3979566,-2.3728392830000002,-3.1826927310000004,0.7303439409999999,-0.041195301000000004,-14.29781639,-12.32993608,-13.92959061,-13.73057261,-14.12534537,-17.37363729,-7.511382192999999,-4.475968388,-12.381511688232422,-12.835992813110352,-13.712812423706055,-13.467306137084961,-14.696981430053711 -2907,2907,D177C,-0.03384615,-0.010968565,-0.042513662,-1.9512715719999998,-3.2068331110000003,0.035554672999999995,-0.043325575,-0.024366724,0.012332127,-0.001311963,-0.020625167,0.011560291,-0.096587614,-1.6328871530000002,-2.26965599,-2.84739074,-3.566275482,0.676165595,0.695076903,-16.71855757,-16.12085495,-17.20444671,-15.527494,-16.35352685,-18.38646533,-7.996072771000001,-5.2650840930000005,-14.677408218383789,-15.831256866455078,-14.331892013549805,-15.591001510620117,-15.855863571166992 -2908,2908,D177E,0.031810139,-0.142519666,-1.3577930319999998,-1.898211186,-2.8871319730000002,-0.045634199,0.036019088,0.02760119,0.02799369,-0.100624641,-0.18441469,-1.4484760730000001,-1.26710999,-1.73411042,-2.062311952,-2.274003349,-3.5002605960000004,3.7510520510000003,2.226345549,-12.98444365,-12.56549814,-12.33393907,-11.69905081,-12.6254398,-15.69829041,-10.38001803,-9.881647741,-12.092084884643555,-11.060678482055664,-10.622333526611328,-9.506643295288086,-13.547736167907715 -2909,2909,D177G,-0.05066527,-0.019145343000000002,-1.5503802119999999,-2.474242629,-3.096966536,0.403053565,-0.044590772,-0.056739767,-0.005068237,-0.040202634,0.001911948,-1.629233626,-1.4715267980000002,-2.0354419040000002,-2.9130433539999996,-2.8349721430000003,-3.358960928,0.984896232,0.001689835,-13.86645578,-11.76493343,-13.79533993,-12.87650214,-13.902781,-16.99272241,-7.157390032,-2.3757715040000003,-12.623820304870605,-12.87531566619873,-12.953006744384766,-12.37854290008545,-14.180694580078125 -2910,2910,D177F,-0.040112678,-1.45863092,-2.239600152,-2.703804636,-2.8454228230000003,0.08675874800000001,-0.031420254,-0.048805102,0.046116649,-1.707865145,-1.209396695,-2.0639000259999998,-2.415300278,-2.2148357990000003,-3.192773473,-2.315396034,-3.3754496119999997,-0.324851548,-1.03246806,-19.30167021,-18.54223775,-20.15716284,-17.19859063,-19.46637615,-21.14398369,-9.564736307999999,-7.424561439,-16.513856887817383,-17.26988410949707,-16.151857376098633,-17.421463012695312,-20.258520126342773 -2911,2911,D177I,-0.039547797999999995,-1.407181644,-2.173694409,-1.8853239030000002,-2.9784870839999997,-0.029232759,-0.032159136,-0.04693645900000001,0.033557843,-1.268532451,-1.545830836,-2.101688587,-2.24570023,-1.951594364,-1.819053442,-2.65421459,-3.302759577,0.260260037,-0.7646454020000001,-18.84272683,-18.46856734,-18.72485277,-17.70716441,-17.28675867,-22.02629095,-8.346648431,-6.332585614,-15.974923133850098,-15.48245906829834,-16.24317169189453,-16.873035430908203,-17.325199127197266 -2912,2912,D177H,-0.057423199999999994,-1.347642099,-2.470607755,-2.42421759,-3.226945425,0.00061601,-0.057239312,-0.057607088,0.048422024,-1.3937092219999998,-1.301574976,-2.3295277000000003,-2.61168781,-2.3043722140000003,-2.544062965,-2.8820537039999996,-3.571837145,-0.332672123,-0.902037139,-13.38927967,-12.34057926,-12.62737952,-11.48412038,-13.46533062,-17.02898856,-6.862055389,-5.009457529,-13.056171417236328,-13.038058280944824,-15.06338119506836,-14.113865852355957,-15.23363971710205 -2913,2913,D177K,-0.07613455200000001,-1.651551649,-2.235122516,-2.670331026,-2.9624642110000003,-0.027912485,-0.058461189000000004,-0.093807914,-0.012706102,-1.464758547,-1.83834475,-2.325943406,-2.144301625,-2.175849184,-3.1648128680000003,-2.577439414,-3.347489008,-0.042119870999999996,-0.931412756,-19.10434258,-17.07863573,-20.78290244,-18.44397006,-17.88225241,-21.33395224,-10.2235114,-9.090818499,-15.965734481811523,-15.905282020568848,-17.19173812866211,-16.309925079345703,-17.417753219604492 -2914,2914,D177M,-0.037824157000000004,-1.631384144,-1.881562351,-2.607206207,-2.7488243939999997,0.285960998,-0.019709687,-0.055938626,-0.055307599000000006,-1.809139963,-1.453628324,-1.670324823,-2.092799878,-2.5202306,-2.694181814,-2.620790835,-2.876857953,-0.469384865,-1.116083105,-18.96438576,-18.42030879,-19.45063929,-18.54661929,-17.26363905,-21.14072237,-8.807471547999999,-6.75638626,-16.125627517700195,-16.506881713867188,-16.307939529418945,-17.09451675415039,-19.216934204101562 -2915,2915,D177L,0.007256453,-1.478178075,-2.121342147,-2.519836198,-3.0365156489999996,0.004879856,0.007511955,0.007000951,0.0022333879999999998,-1.5357041790000001,-1.4206519709999998,-2.046641021,-2.196043272,-2.0884323240000002,-2.951240072,-3.143235068,-2.929796229,-0.150182889,-0.971961803,-18.68623285,-17.79818128,-20.19349654,-17.64153305,-16.67184169,-21.12611169,-8.152707216,-6.072712942000001,-15.25811767578125,-17.386337280273438,-15.713752746582031,-16.48306655883789,-18.551921844482422 -2916,2916,D177N,-0.017075801,-0.000158119,0.020908438,-2.070950394,-3.039174838,0.51936255,-0.034688993,0.0005373919999999999,-0.009583795,-0.053688603,0.053372366,0.0030910770000000002,0.038725798,-1.666358636,-2.475542151,-2.72116138,-3.357188295,0.5810482260000001,0.686829747,-9.327629109,-8.96271405,-8.139175437999999,-9.654137802000001,-8.485027817,-11.39709044,-5.162531784,-0.089085383,-8.916150093078613,-9.488642692565918,-10.685364723205566,-9.888259887695312,-11.071807861328125 -2917,2917,D177Q,-0.029995821000000002,-1.198458333,-2.06711849,-2.4063842369999997,-2.999547418,0.002064553,-0.028396279,-0.031595363,0.045269245,-1.288324378,-1.108592287,-1.614396036,-2.519840943,-2.54348306,-2.269285414,-2.6440432940000003,-3.3550515410000004,2.718566902,0.6131566999999999,-16.24939426,-15.58312479,-16.40857986,-14.11960248,-17.36409329,-17.77157085,-8.388554693,-6.072712742999999,-14.922042846679688,-15.095287322998047,-15.146114349365234,-14.734606742858887,-17.180206298828125 -2918,2918,D177P,-0.054703996,-1.6308598630000002,-2.136533618,-2.2329946830000003,-2.955764358,0.017016641000000002,-0.034895108,-0.074512884,-0.042048714,-1.7878946219999998,-1.473825104,-2.1581699430000003,-2.1148972930000003,-1.9111657069999999,-2.554823658,-2.58575721,-3.325771505,-0.223047351,-1.0872948070000001,-16.71263022,-16.22572065,-17.16447638,-15.55302508,-16.1109048,-18.50902417,-7.792280456,-4.629567453,-17.41572380065918,-18.340572357177734,-16.803415298461914,-17.806657791137695,-20.621109008789062 -2919,2919,D177S,-0.040726507,-0.07135499599999999,-1.4137530230000002,-2.164127034,-3.044305848,0.004625543,-0.038938468999999996,-0.042514545,-0.033411471,-0.057048655,-0.08566133599999999,-1.4566244259999999,-1.37088162,-1.94998288,-2.3782711869999997,-2.624574383,-3.464037313,2.76557031,1.203364473,-14.02711028,-12.70172464,-14.80113695,-12.58582555,-12.76977471,-17.27708955,-6.590139751000001,-2.906208201,-11.815149307250977,-14.692389488220215,-12.817289352416992,-14.250670433044434,-14.748922348022461 -2920,2920,D177R,-0.040080099,-1.58093661,-2.069675444,-2.3295633430000002,-3.254302042,0.026025867999999997,-0.025559633999999998,-0.054600563,0.008478656999999999,-1.691854191,-1.4700190290000001,-1.854069046,-2.285281842,-2.0671527259999998,-2.59197396,-2.804535058,-3.704069025,-0.555157375,-1.06493945,-15.28279183,-15.03369551,-14.868789600000001,-14.6361579,-15.15395259,-16.72136355,-8.268776969,-5.669493051,-16.07411003112793,-16.355770111083984,-17.391983032226562,-17.78154754638672,-18.284526824951172 -2921,2921,D177T,-0.037308838,-0.889491313,-2.241938641,-2.531019115,-3.24570132,0.00433985,-0.025310124,-0.049307551,0.038496493,-0.860049115,-0.91893351,-2.194720945,-2.289156336,-1.898498686,-3.163539543,-3.145186957,-3.346215683,0.835632919,-0.533736591,-15.52140162,-14.15837387,-16.6662601,-14.83309168,-14.50199335,-17.44728909,-7.483252257,-3.12611923,-13.591811180114746,-14.078195571899414,-12.56827449798584,-14.861321449279785,-16.520816802978516 -2922,2922,D177W,-0.004003598,-1.293930152,-2.2275420969999997,-2.512235609,-3.193444419,-0.082693571,-0.01816347,0.010156274,0.092009779,-1.4421690719999998,-1.145691231,-2.2848705259999997,-2.170213667,-2.310867562,-2.713603655,-2.712457792,-3.674431045,-0.116619183,-0.898743893,-19.05736052,-18.10889854,-18.69110889,-17.70557104,-19.22812548,-21.55309866,-10.38829928,-9.900579667999999,-17.851219177246094,-19.058412551879883,-18.204849243164062,-19.333223342895508,-20.15750503540039 -2923,2923,D177V,-0.004413096,-1.392795112,-2.251957696,-2.273133856,-3.264237045,0.013170095,0.00565829,-0.014484481,0.015897236000000002,-1.4737212869999998,-1.311868937,-2.1450266030000003,-2.3588887880000002,-2.074113627,-2.472154084,-2.697552607,-3.830921483,-0.007956959,-0.9253108940000001,-17.61909881,-17.15531444,-17.31167806,-17.08289298,-15.96140543,-20.58420312,-8.600667907,-6.357603388999999,-13.869977951049805,-13.478245735168457,-13.566452026367188,-14.543106079101562,-16.380617141723633 -2924,2924,D177Y,-0.026625222999999996,-1.440494156,-1.573095255,-2.651457135,-2.3811209509999998,0.26567847,-0.035415302999999995,-0.017835142,0.03599238,-1.652461745,-1.228526567,-1.6105566180000002,-1.535633891,-2.1294691759999997,-3.173445093,-2.008180661,-2.754061241,4.151501698,1.881614181,-19.24181579,-18.29333009,-20.33169232,-16.84428907,-19.51461633,-21.22515112,-10.196313900000002,-9.092938945,-14.918033599853516,-14.060843467712402,-14.945499420166016,-14.962862968444824,-15.70263671875 -2925,2925,T178A,-0.03697258,-0.01025819,-0.05929755900000001,-0.666725184,-2.022396221,-0.067034385,-0.03186832,-0.042076839000000005,0.000912627,-0.052362275,0.031845895,-0.09463138,-0.023963738,-0.314931378,-1.0185189890000002,-1.784820715,-2.259971726,1.4962101280000002,1.388526479,-7.5025105420000004,-7.013764388999999,-7.761388725,-6.662048882000001,-8.340127289,-7.735223427,-7.22138722,-2.695679955,-12.077777862548828,-10.685823440551758,-11.030006408691406,-10.108983039855957,-11.068167686462402 -2926,2926,T178C,-0.003452309,0.022467565,-0.006093559,0.026023947000000002,-1.6754330919999998,-0.045349138,0.010440386,-0.017345003,-0.049738375,-0.014416,0.059351129,-0.06807876,0.055891643,0.016239738,0.035808156,-1.47370052,-1.8771656630000002,0.824484043,1.331275808,-10.492131599999999,-9.741372475,-12.29367126,-9.133995049,-10.94033076,-10.35128847,-8.811347112,-5.556098323,-13.508170127868652,-14.788309097290039,-11.569978713989258,-12.27131175994873,-12.801701545715332 -2927,2927,T178E,-0.016937156999999998,-0.000344385,-1.103886423,-2.109838908,-2.343746274,-0.071994275,-0.012741378000000001,-0.021132935,0.09272398300000001,-0.050796901,0.050108132,-0.8831370620000001,-1.324635783,-1.72250317,-2.497174646,-2.3261051669999997,-2.361387381,3.059225959,1.758831309,-11.75023141,-11.15071449,-12.37046675,-10.2852391,-13.60105926,-11.34367744,-8.027812092000001,-3.564414251,-14.277172088623047,-11.586576461791992,-14.42052173614502,-12.10428524017334,-14.757288932800293 -2928,2928,T178D,-0.022743938999999998,-0.078639435,-0.8682324290000001,-1.976704964,-2.8637175839999998,-0.039652777,0.004836025,-0.050323902000000004,-0.0028074320000000003,-0.11326253900000001,-0.04401633,-0.606403739,-1.130061118,-1.715872591,-2.237537336,-2.962927265,-2.764507903,1.989588289,0.944588612,-13.413217999999999,-12.50605766,-15.38231866,-11.48832662,-14.96376373,-12.72562331,-9.296412006,-5.612057393,-13.603516578674316,-11.423145294189453,-14.11785888671875,-12.936456680297852,-15.681544303894043 -2929,2929,T178G,-0.03650891,-0.028961538,-0.16918995399999998,-1.7414818840000001,-2.549241462,-0.07348450599999999,-0.032556597,-0.040461223,0.035529476000000004,-0.074400118,0.016477042,-0.18543152100000002,-0.152948387,-1.4748046019999999,-2.008159165,-2.593316415,-2.505166509,1.273035993,0.778656743,-7.316514032000001,-7.4031984710000005,-6.319113762000001,-7.155837547000001,-6.944204147000001,-8.760216232000001,-7.20122836,-3.217917593,-14.02778434753418,-14.907112121582031,-12.40243148803711,-10.532499313354492,-14.537114143371582 -2930,2930,T178F,0.019355587,0.038974695,-1.042183748,-1.979926957,-2.86912198,-0.090820779,0.068454157,-0.029742982999999997,0.120552538,0.06893241900000001,0.00901697,-0.704019348,-1.3803481480000002,-1.765234206,-2.1946197069999998,-2.572956186,-3.165287773,1.990801515,0.931855393,-15.12077276,-12.88565914,-18.11985852,-11.88559626,-17.58413857,-15.12861132,-8.204962869,-3.7215851339999997,-14.18544864654541,-15.353023529052734,-11.225720405578613,-13.874078750610352,-17.08281707763672 -2931,2931,T178I,0.0007364060000000001,-0.041134244,-0.030404400000000005,-1.1708358540000001,-2.0425981159999997,-0.058753062,0.063443801,-0.061970989000000004,-0.067649964,-0.21180971399999998,0.129541226,-0.06514049200000001,0.004331693,-0.853665511,-1.4880061969999998,-1.891836412,-2.19335982,2.2776363219999998,1.644127827,-10.41823583,-9.8630392,-11.86712547,-7.999804581,-13.63960155,-8.721608345,-6.649185841,-3.40908366,-12.476673126220703,-10.099201202392578,-9.866837501525879,-10.124418258666992,-10.739542007446289 -2932,2932,T178H,0.0005205769999999999,0.024717927,-1.111527005,-1.9265255190000001,-2.450143199,-0.055416713,0.040809223,-0.039768068999999996,-0.012970483,0.026397423,0.02303843,-1.006565208,-1.216488802,-1.9601461869999999,-1.892904851,-2.767868167,-2.13241823,2.383297662,1.049441673,-13.65985964,-10.27864773,-16.0813147,-10.12547282,-15.91915819,-15.89470478,-8.224240842,-4.217772212,-14.390027046203613,-14.170079231262207,-12.658008575439453,-14.28158187866211,-15.854362487792969 -2933,2933,T178K,0.032266966,0.010882636000000001,-1.082954741,-1.99529304,-2.986548055,-0.083049002,0.056949239000000006,0.007584692,-0.039758251,-0.056148862,0.07791413400000001,-0.905966026,-1.259943455,-1.633150628,-2.357435452,-2.741902604,-3.231193505,2.365292051,1.154256435,-11.19116639,-10.86616194,-11.93956719,-9.855000443,-12.25556516,-11.03953719,-8.319398361000001,-2.996720873,-13.767508506774902,-12.010522842407227,-13.376769065856934,-12.7080078125,-13.292800903320312 -2934,2934,T178M,-0.159316091,-0.061484069,-0.16277402,-2.053647471,-2.8319181189999996,-0.013901697,-0.151496616,-0.16713556599999999,-0.0068101740000000004,-0.09509483199999999,-0.027873306,-0.19300239,-0.13254565,-1.4177713,-2.689523641,-2.22549328,-3.4383429580000002,2.44000034,1.5028857880000002,-12.05448831,-10.92130016,-13.46398085,-10.87705202,-14.12015848,-10.88995006,-8.851335481,-4.057826899,-11.80114459991455,-11.276902198791504,-11.579863548278809,-10.609658241271973,-12.064784049987793 -2935,2935,T178L,-0.005406741,0.023695416,-0.847496625,-2.061029743,-2.776831022,-0.041987435,0.030624997999999997,-0.04143848,0.027525247000000003,-0.054830529,0.10222136,-0.510537343,-1.184455906,-1.7196141719999998,-2.4024453130000003,-2.754579933,-2.799082111,1.789926526,0.862800013,-10.55280929,-9.718879784,-12.41741207,-9.020177841,-12.91728638,-8.690290352,-6.726409267999999,-2.972375323,-13.503652572631836,-12.933205604553223,-11.580803871154785,-11.979162216186523,-13.216780662536621 -2936,2936,T178N,-0.075980108,-0.091732399,-0.250229729,-1.4884104180000002,-2.2611833740000002,-0.084548093,-0.074040269,-0.077919947,0.11812856199999999,-0.14138967300000002,-0.042075125,-0.27941978300000003,-0.221039675,-1.5248873790000002,-1.451933456,-2.383761881,-2.138604866,1.5275508169999998,0.836838192,-10.75136899,-10.41841404,-10.40395026,-9.562482758,-12.6922366,-10.67976128,-8.714224377999999,-5.445278977,-11.684632301330566,-11.186111450195312,-11.089948654174805,-10.998096466064453,-12.774518013000488 -2937,2937,T178Q,0.006552982,0.021178347,-0.057128605,-1.683283735,-2.094211605,-0.08975299199999999,0.008790377,0.004315587,0.006039711999999999,0.01672176,0.025634933999999998,-0.092672314,-0.021584896,-1.493964918,-1.872602551,-2.067603692,-2.1208195169999997,0.8482688509999999,0.7158921229999999,-11.47798253,-10.22602359,-11.54844435,-9.838138466,-12.69812693,-13.07917931,-7.630618371000001,-2.7659674869999997,-13.9490327835083,-12.956110000610352,-14.157217025756836,-13.071515083312988,-13.804309844970703 -2938,2938,T178P,-0.00169372,-1.441202914,-2.1892916159999998,-2.06671496,-2.8639030869999997,-0.07135773599999999,0.001721331,-0.005108771,-0.028500872000000003,-1.5042824240000001,-1.378123403,-2.264243782,-2.114339449,-1.953006939,-2.180422981,-2.821426759,-2.906379415,-0.139205876,-0.9568155359999999,-12.91759115,-12.02074955,-14.03083274,-11.45113136,-14.31534618,-12.76989589,-10.05107184,-6.781916575,-15.934453010559082,-14.665173530578613,-13.770671844482422,-15.347085952758789,-17.210147857666016 -2939,2939,T178S,-0.003441828,0.0068446340000000005,-0.035690469,0.013058796000000001,-0.131550732,-0.015353438,-0.011624938999999999,0.004741283,0.039652913,-0.038237607,0.051926874000000005,-0.083948522,0.012567585,0.008561019,0.017556572,-0.138716851,-0.124384613,1.385479405,2.213557418,-4.3258371030000005,-3.573637657,-4.60095491,-3.9077006069999998,-5.778857071,-3.768035271,-5.428455129,-1.9022832680000001,-7.938476085662842,-9.55974006652832,-6.109370231628418,-7.938251495361328,-9.191705703735352 -2940,2940,T178R,-0.025958626000000002,0.010140992,-1.297399273,-2.1593434869999997,-3.014521567,-0.039309601,-0.005521028000000001,-0.046396223,0.026489515,-0.026880177999999998,0.047162160999999994,-1.023374368,-1.5714241780000002,-2.052790334,-2.26589664,-2.537205923,-3.4918372110000004,2.14159828,0.839493752,-11.59679735,-8.757783035,-12.55387045,-10.01925752,-13.36581464,-13.28726111,-6.627665226,-2.4471077130000003,-14.468727111816406,-13.150050163269043,-12.630149841308594,-12.971243858337402,-12.06816291809082 -2941,2941,T178W,-0.03968747,-0.8114099770000001,-1.9583773469999999,-2.182161219,-3.2135716089999997,-0.08717100400000001,-0.02886437,-0.05051057,0.036422341000000004,-0.660259155,-0.962560799,-1.9475083780000002,-1.969246316,-1.956606685,-2.407715752,-2.6016013669999998,-3.82554185,1.604975157,-0.025735342,-14.01355529,-10.822115,-17.47463041,-11.83934553,-14.66753101,-15.26415453,-8.273587702999999,-2.075366433,-16.241973876953125,-16.795251846313477,-10.31568717956543,-14.631902694702148,-16.325550079345703 -2942,2942,T178V,-0.035448279,-0.007799815999999999,-0.02147337,-0.732749027,-2.349552164,-0.0632658,-0.023071717000000002,-0.04782484,0.011322399999999998,-0.04280928,0.027209649,-0.082907378,0.039960638,-0.339526895,-1.125971159,-2.1161763419999997,-2.582927986,1.4635339719999998,1.331094486,-8.949479036,-9.008019516000001,-9.306102806,-7.444343787999999,-11.92293259,-7.065996475,-6.847592357000001,-2.52747589,-11.719438552856445,-11.476158142089844,-11.077706336975098,-10.380489349365234,-10.197490692138672 -2943,2943,T178Y,-0.032703631000000004,0.029025183,-1.155732099,-2.469291866,-2.946532519,-0.019010945,0.012512685,-0.077919947,0.11011059,0.0188679,0.039182466,-0.656960112,-1.654504085,-1.96272361,-2.975860122,-2.645506853,-3.247558184,1.795647575,0.77819285,-15.35096205,-11.55716823,-19.14184499,-11.18590287,-17.06402663,-17.80586755,-7.823560892000001,-2.118714087,-13.90111255645752,-15.082019805908203,-10.567672729492188,-14.3502836227417,-15.785677909851074 -2944,2944,T179A,0.046224395,-0.034006388,-0.184595751,-1.5130488869999998,-1.6994956,-0.097910391,0.013945239,0.07850355,0.009869948,-0.14155141699999998,0.073538642,-0.341185054,-0.028006447,-1.54341548,-1.482682293,-1.756056227,-1.642934972,3.726344202,2.714467013,-5.8438479889999995,-8.64626722,-5.965363625,-4.910584366,-4.901592003,-4.795432732,-6.170942619,-1.78980376,-9.214250564575195,-7.866142272949219,-7.077300071716309,-6.673408508300781,-9.34614086151123 -2945,2945,T179C,-0.049214392999999995,-0.073504932,0.035947226,-0.5907637370000001,-2.572330785,-0.031309429,-0.030145346,-0.06828344,0.041238061,-0.259473637,0.112463773,-0.16937926,0.241273711,-0.48031122299999995,-0.70121625,-2.508529719,-2.636131851,1.41598106,1.171384054,-9.565857422,-9.471306709,-11.46705871,-8.732470367000001,-10.22974149,-7.928709831,-6.901180172999999,-4.175655389,-12.159866333007812,-11.84326171875,-9.923227310180664,-10.016056060791016,-10.708084106445312 -2946,2946,T179E,0.012978503,-1.875414462,-2.481677151,-1.923231694,-3.131540263,-0.072050143,0.040023084,-0.014066078999999999,-0.072041998,-2.04604899,-1.704779934,-2.8479470410000003,-2.115407261,-2.062766594,-1.783696793,-2.956648579,-3.3064319460000005,-0.359593094,-1.1574791690000001,-12.78221337,-13.73978926,-13.70065312,-12.21706234,-12.14180316,-12.11175899,-10.68517917,-10.18987442,-15.95470905303955,-13.083969116210938,-13.411030769348145,-15.044503211975098,-14.710500717163086 -2947,2947,T179D,0.09151922,-1.5481259440000001,-2.477151476,-2.575338244,-2.7044655669999997,-0.133196924,0.09878971199999999,0.084248727,-0.063712592,-1.76322738,-1.333024508,-2.468215418,-2.486087534,-2.586124958,-2.56455153,-2.576916956,-2.832014178,-0.330365872,-1.096292652,-11.93087944,-12.24223439,-13.13375864,-11.28712727,-11.75428349,-11.236993400000001,-9.504102092,-7.616943493,-14.996481895446777,-10.306297302246094,-13.748407363891602,-14.898475646972656,-14.794937133789062 -2948,2948,T179G,0.049456347000000005,-0.521488732,-1.6614721680000002,-2.159479019,-2.870286433,-0.086859955,0.030095731,0.068816963,0.029438107999999998,-0.436986072,-0.6059913920000001,-1.92799038,-1.394953956,-2.221991178,-2.096966859,-2.7925667730000003,-2.948006093,1.35074276,-0.048739024000000006,-10.47686178,-12.81975514,-10.51406255,-8.826246361,-10.27706812,-9.947176743,-7.421709612000001,-2.512771379,-11.582088470458984,-11.342982292175293,-9.727120399475098,-11.177445411682129,-13.030973434448242 -2949,2949,T179F,-0.057359255,-1.241090351,-2.102766596,-1.899923368,-2.3300806869999997,-0.029462931,-0.086180462,-0.028538047999999996,-0.132739838,-1.538492942,-0.94368776,-1.942450985,-2.263082207,-1.458300533,-2.341546203,-2.0511525219999998,-2.609008851,4.447149512,2.146055538,-13.66231712,-14.83172106,-14.70609365,-13.40496555,-15.36751414,-10.00129122,-8.241111027999999,-5.475248998,-14.769583702087402,-16.150745391845703,-13.563028335571289,-14.405861854553223,-14.73709487915039 -2950,2950,T179I,0.11141049800000001,-0.028284634,-1.7451606119999998,-1.780878011,-1.472474702,0.114060975,0.144961393,0.077859603,-0.103968096,-0.081575074,0.025005807,-1.455569893,-2.03475133,-2.0506006869999998,-1.511155335,-1.56427143,-1.3806779740000001,4.204330134,2.6432110719999997,-9.269183092,-10.01742411,-10.88942033,-8.53746151,-11.49598026,-5.40562925,-6.6276994270000005,-2.9091971780000003,-11.69269847869873,-10.166686058044434,-10.374897003173828,-9.342562675476074,-10.581311225891113 -2951,2951,T179H,0.012877772,-1.303707478,-1.676213252,-2.376460011,-2.505587335,0.059222059,0.008978360999999999,0.016777181999999998,-0.116578179,-1.788370416,-0.8190445390000001,-2.192328458,-1.1600980459999999,-2.3102379969999998,-2.442682025,-2.301029996,-2.7101446730000003,0.141101471,-1.075798029,-13.95466253,-14.28363422,-14.51824043,-12.9535786,-14.23689232,-13.78096706,-10.67763656,-10.15915838,-15.0460786819458,-16.60470199584961,-13.904336929321289,-16.286128997802734,-16.098735809326172 -2952,2952,T179K,-0.011041428,-1.8222090130000002,-2.100719546,-1.82872497,-2.108367291,0.048145843,0.031302258,-0.053385113,-0.142445147,-2.258192432,-1.3862255940000001,-2.361120478,-1.840318614,-2.178000022,-1.479449917,-2.4698220159999997,-1.746912565,-0.346455695,-1.195983602,-13.45336046,-13.61319967,-14.91137661,-12.61603802,-13.06823528,-13.05795271,-10.68517917,-10.18987442,-15.506993293762207,-15.891792297363281,-15.066404342651367,-17.034992218017578,-16.115079879760742 -2953,2953,T179M,0.051896884000000004,-0.34882832700000005,-1.243939065,-1.644658584,-1.436712697,-0.14946847900000002,0.02027316,0.083520607,-0.052177685999999994,-0.392206665,-0.305449989,-1.581494542,-0.906383587,-2.09734409,-1.191973077,-1.69019608,-1.183229313,4.55421996,2.8408835310000002,-11.92121004,-13.05763191,-13.21479869,-11.66723624,-12.90897221,-8.757411133,-7.632178917999999,-4.671417629,-11.5203218460083,-12.06813907623291,-11.584476470947266,-10.044384002685547,-12.093317985534668 -2954,2954,T179L,0.0467481,-0.659976033,-1.89705447,-1.961767843,-2.7520048139999997,-0.08142222,0.019748398,0.073747802,0.013447168999999998,-0.602659211,-0.717292855,-2.391328996,-1.402779943,-2.3331472769999997,-1.590388409,-2.323939275,-3.180070352,0.35688753100000004,-0.526893457,-13.51458116,-14.19646787,-15.41489374,-13.4997104,-15.50864189,-8.953191879,-8.188619927000001,-5.50696152,-12.385831832885742,-13.484384536743164,-11.608577728271484,-11.871045112609863,-12.450380325317383 -2955,2955,T179N,0.134326907,-1.630328298,-2.092827224,-2.191013992,-2.320141315,-0.063187442,0.105464825,0.163188989,0.00038234699999999995,-1.978702114,-1.2819544809999999,-2.08163016,-2.1040242869999997,-2.1995397,-2.182488284,-2.190331698,-2.4499509319999997,-0.48914258,-1.1090614109999999,-10.20093108,-10.10105673,-10.35465483,-10.17658924,-10.52864664,-9.843707977000001,-8.673711929,-6.884448012999999,-12.149453163146973,-11.89781665802002,-11.301498413085938,-12.770147323608398,-12.502437591552734 -2956,2956,T179Q,-0.015754079,-1.576327813,-1.9903717330000001,-2.4380435030000003,-2.7176858239999997,-0.079204905,-0.019437492,-0.012070666,-0.07939943,-2.031408464,-1.1212471609999999,-2.134336511,-1.846406954,-2.25224605,-2.623840955,-2.544068044,-2.8913036030000003,-0.657770297,-1.14687837,-13.65205633,-14.67012868,-14.11962594,-13.06034309,-13.52339722,-12.88678672,-10.68517917,-10.18987442,-14.36128044128418,-15.423785209655762,-13.798047065734863,-15.434551239013672,-14.794731140136719 -2957,2957,T179P,0.048037519,-1.255365937,-1.751160922,-1.627013075,-1.894521109,-0.050044702,0.016876849,0.079198188,-0.110979975,-1.814699354,-0.6960325190000001,-2.6957786510000004,-0.806543193,-2.336566936,-0.9174592140000001,-2.804480189,-0.9845620279999999,-0.33721347799999996,-1.1339176359999998,-13.30512378,-14.61875855,-13.72397119,-12.90649961,-13.06696815,-12.20942139,-10.52067966,-9.329510657,-15.4747314453125,-16.442655563354492,-11.850152015686035,-14.55253791809082,-15.643993377685547 -2958,2958,T179S,0.050563725,-0.033441299,-0.016904334,-0.013030818999999999,-0.230557033,-0.10655780699999999,0.010161224,0.090966225,0.018490432,-0.167483567,0.10060097,-0.19897595199999998,0.165167284,-0.21752623399999998,0.19146459600000001,-0.278533761,-0.182580305,1.520701975,2.0156421669999998,-3.07001349,-4.10689785,-3.909756836,-2.394115967,-2.675653084,-2.263643715,-3.048891732,-1.006407282,-6.032432556152344,-5.636932373046875,-5.491564750671387,-5.866602897644043,-4.973054885864258 -2959,2959,T179R,0.032514294,-1.5332803330000002,-2.152483282,-2.102102574,-2.425682559,-0.047581306,0.029446135,0.035582453,-0.066826989,-1.7905364769999998,-1.2760241890000001,-2.291404533,-2.0135620309999998,-2.35816155,-1.846043598,-2.40010607,-2.4512590480000003,-0.387092355,-1.104469924,-14.185531699999999,-15.46951534,-13.9636358,-13.91841853,-13.70309732,-13.87299149,-10.68517917,-10.18987442,-14.903656005859375,-15.098127365112305,-14.707090377807617,-16.34212875366211,-15.244219779968262 -2960,2960,T179W,-0.160617163,-1.630715744,-2.390331997,-2.639033763,-2.981145452,0.068954846,-0.094602604,-0.226631721,-0.045164769,-1.710765558,-1.550665929,-2.85508629,-1.9255777040000002,-2.6719658330000002,-2.6061016919999997,-2.963787827,-2.998503077,-0.235915717,-1.0792687970000001,-14.43779244,-14.70340348,-15.49979241,-14.19424425,-15.32971284,-12.46180922,-9.213889826,-6.969712011,-17.918277740478516,-18.964397430419922,-15.058886528015137,-17.38484764099121,-16.701068878173828 -2961,2961,T179V,0.012128883,-0.058741129,-0.387666413,-2.003287679,-2.521490628,-0.029620795,0.008738108,0.015519658,-0.032369293,-0.18819049,0.070708232,-0.418261019,-0.357071807,-1.8966377419999998,-2.109937616,-2.364550995,-2.67843026,1.6294385930000002,0.766679228,-8.930573801,-10.85512756,-10.00932064,-8.199188515,-10.54125449,-5.047977798,-7.511814427999999,-3.134082269,-11.17078971862793,-9.591304779052734,-10.07929801940918,-9.215621948242188,-10.849910736083984 -2962,2962,T179Y,0.077284132,-1.522037125,-2.135051049,-1.693647194,-2.36236514,-0.31660366100000004,0.141928553,0.012639711000000001,-0.152335394,-1.704824364,-1.339249885,-2.108782406,-2.161319691,-1.624631955,-1.762662433,-2.217483944,-2.507246335,-0.105173396,-1.096946164,-15.91530202,-16.65486102,-17.0069881,-15.08405989,-16.819863199999997,-14.01073789,-10.68517917,-10.18987442,-16.489086151123047,-17.400053024291992,-14.477425575256348,-16.337997436523438,-15.616104125976562 -2963,2963,M180A,0.008215116,-0.10665884099999999,-0.058799686,-0.018438764,-0.127120803,-0.03369834,-0.069038768,0.085468999,-0.025102365,-0.109792358,-0.103525323,-0.08330580900000001,-0.034293563,-0.060150237999999995,0.023272711,-0.101332826,-0.152908779,1.522361272,2.396863212,1.091029861,0.839207947,0.965141968,0.656144539,2.549608978,0.445045876,-3.253398392,1.8794693230000001,-2.250481367111206,-3.5209243297576904,0.6452441215515137,0.1732473373413086,-0.9244718551635742 -2964,2964,M180C,-0.17364243899999998,-0.074819542,-0.038632127,-0.044083199,-0.117845373,-0.10559689300000001,-0.24841296,-0.09887191699999999,-0.037071311,-0.070126153,-0.079512931,-0.00975172,-0.067512533,-0.049865243,-0.038301154,0.012459399,-0.248150144,1.1765857709999998,2.5441896880000003,-3.036060364,-3.825002327,-2.274353386,-4.606796455,-1.978913582,-2.495236069,-4.212939077,1.755521637,-4.370064735412598,-6.105049133300781,-0.419095516204834,-2.979280948638916,-3.286642551422119 -2965,2965,M180E,0.060155235999999994,-0.06130517,0.029652502,-0.005679826,-0.04394987400000001,-0.0241386,-0.014978671,0.135289142,-0.038337846,-0.064833865,-0.057776474,0.047726628,0.011578375,-0.026477461,0.01511781,-0.063644971,-0.024254776000000002,1.177169581,2.264657126,-2.833061012,-3.273310051,-1.95759153,-3.94892128,-2.875169098,-2.110313103,-4.812177481,0.5022367529999999,-4.858757972717285,-6.215239524841309,-2.7562904357910156,-2.4329681396484375,-3.2435145378112793 -2966,2966,M180D,-0.177434819,-0.033802104,0.027280211000000002,0.003269307,-0.39934093,-0.122231075,-0.255733056,-0.099136581,0.004468816,0.011311442,-0.078915649,0.054384287,0.000176135,-0.022982051,0.029520664,-0.189061742,-0.6096201170000001,1.4720809240000001,2.185546032,-3.168685245,-4.3458514710000005,-3.0813708269999998,-4.416568024,-2.95901931,-1.0406165920000001,-4.248461785,0.48121629299999996,-3.42802357673645,-6.500443458557129,-2.1765365600585938,-2.6183786392211914,-3.4942736625671387 -2967,2967,M180G,0.02159364,-0.09698127,0.012540552,0.006400223000000001,-0.192624745,-0.067349739,-0.144202078,0.187389358,-0.010244841999999999,-0.067990057,-0.125972483,0.054606192000000005,-0.029525088999999997,0.006745484,0.006054962,-0.098737868,-0.28651162199999997,1.37136561,2.355056469,-2.634155504,-2.8252048189999996,-1.850834656,-3.848986977,-1.1446454240000001,-3.501105644,-5.563584284,-1.163148938,-4.7328033447265625,-7.483161926269531,-2.1527576446533203,-2.5819339752197266,-3.3303675651550293 -2968,2968,M180F,-0.137961776,-0.073684493,-0.003725579,-0.002144089,-0.296461378,-0.062312282000000004,-0.24364506800000002,-0.032278483999999996,-0.07220663299999999,-0.040356768,-0.107012218,0.09272474800000001,-0.100175905,-0.050662845,0.046374667,-0.212769092,-0.380153664,1.339979813,2.030862812,-5.143784602,-5.451436256,-4.207999901,-7.755996933,-3.907310341,-4.396179581,-7.092650281,-4.335715261,-4.935086250305176,-8.077662467956543,-3.2656936645507812,-3.775761127471924,-5.730778217315674 -2969,2969,M180I,-0.17523204899999997,-0.096711958,0.023511436,-0.016955155,-0.22452319399999998,-0.090462333,-0.282816057,-0.06764804,-0.082307511,-0.10730355800000001,-0.086120357,0.09821420199999999,-0.05119133,0.0014348229999999998,-0.035345133,-0.122807939,-0.326238448,1.169010989,2.087660019,-2.2720437999999996,-2.501510033,-2.1388868480000003,-2.2782956469999998,-2.350624977,-2.090901497,-5.855717451,-1.430334393,-2.47670578956604,-4.450037956237793,-1.0835976600646973,-1.9511117935180664,-1.8894553184509277 -2970,2970,M180H,0.28945582,-0.08986669800000001,0.031378431,0.02238592,-0.061344188,-0.019527701,-0.090929009,0.669840648,0.080077623,-0.004308869,-0.17542452600000003,0.052520283,0.010236578,0.044229715999999995,0.0005421240000000001,-0.015279688,-0.107408688,1.256750483,2.6500553,-3.888426958,-5.178946655,-2.947540154,-6.341737952999999,-2.375853256,-2.59805677,-5.01282071,0.061475632999999995,-4.467062950134277,-7.595312118530273,-2.358522415161133,-2.338965892791748,-3.4136500358581543 -2971,2971,M180K,0.039312705,-0.116649048,-0.041719726,-0.035898887000000004,-0.125447739,0.02902923,-0.10790811199999999,0.18653352199999998,-0.039019485,-0.110229824,-0.12306827199999999,0.06395716900000001,-0.14739662,-0.056104497999999996,-0.015693276000000003,-0.094217154,-0.156678323,1.344368611,2.303353519,-1.7531618530000002,-2.333038963,-0.640192879,-3.2494305110000004,-0.9213417890000001,-1.6218051219999998,-4.3529305019999995,1.252429639,-3.7469441890716553,-6.422859191894531,-1.8172645568847656,-1.6674079895019531,-2.211291790008545 -2972,2972,M180L,0.173486957,-0.043903289000000005,0.013349803,0.008802413,-0.36966322700000004,-0.013837763999999999,-0.058916825,0.405890739,-0.010640203999999999,-0.04958979,-0.038216788,0.016918341,0.009781264,-0.022956186,0.040561012,-0.297907832,-0.44141862200000004,1.6465103680000002,2.155408192,-1.7630885509999998,-2.2119883419999997,-1.5658427119999998,-1.395887825,-2.436505859,-1.205218018,-4.894440691000001,-0.58010352,-2.98160719871521,-4.705394744873047,-1.1806159019470215,-1.0558552742004395,-1.2413945198059082 -2973,2973,M180N,-0.15234288599999998,-0.013869412,0.089519141,0.045360487000000005,-0.097824551,-0.025053282000000003,-0.23503605800000002,-0.069649713,0.037788561,-0.010660885,-0.017077939,0.166611058,0.012427223999999999,0.036308645,0.054412329,0.041264341,-0.236913442,1.543610422,3.106887046,-1.740152194,-2.544612305,-0.807760422,-3.898207787,-1.863386719,0.413206261,-3.605959879,1.395519366,-1.592726469039917,-4.794517517089844,0.6775145530700684,0.5914583206176758,-1.0870919227600098 -2974,2974,M180Q,0.824528157,-0.109708877,0.061642395,0.084655964,0.012836888000000001,-0.048919810999999994,0.174265148,1.474791165,0.026832804,-0.061980579,-0.157437174,0.041120486,0.082164303,-0.02497842,0.194290348,0.024319623999999998,0.0013541520000000002,1.1691185590000002,2.719743615,-1.858476291,-2.652852974,-0.990546577,-2.641682213,-1.9173121569999998,-1.089987534,-4.3677654939999995,0.6053690070000001,-4.263882637023926,-6.298711776733398,-2.251314163208008,-1.349843978881836,-2.1692042350769043 -2975,2975,M180P,0.270050771,-0.073583678,-0.073800273,-0.7678384,-1.07766428,-0.08808166099999999,-0.07553401400000001,0.615635555,-0.01053098,-0.063618023,-0.083549333,-0.105932339,-0.041668206,-1.499512912,-0.036163888,-2.064638692,-0.090689868,2.627244526,1.67407162,-1.95131579,-1.337159477,-1.771884178,-3.429864822,-1.115733612,-2.1019368590000003,-4.499697613,0.40678485,-4.934267044067383,-6.945018768310547,-0.14095067977905273,-1.2954959869384766,-2.880466938018799 -2976,2976,M180S,-0.012612296,-0.039474102000000004,0.041602301,0.069145843,-0.033144855,-0.056211765999999996,-0.069622843,0.044398252,-0.010363337,-0.023323429,-0.055624775,0.037735647000000004,0.045468955,0.038173095,0.10011859099999999,0.05582306099999999,-0.12211277,1.1570928329999999,2.724819397,3.373192923,4.326895508,3.789994797,1.311933609,4.0986950680000005,3.338445633,-1.5934346169999998,4.733808609,1.2287914752960205,-0.2005019187927246,4.5294084548950195,3.4042110443115234,2.78806734085083 -2977,2977,M180R,0.20596272399999999,-0.101795828,-0.024229855,-0.003690476,-0.14570540199999998,-0.004266155,-0.058513869,0.470439317,0.012575999,-0.063020753,-0.140570903,0.006324581,-0.05478429,-0.0036083070000000003,-0.003772645,-0.11941776800000001,-0.17199303600000002,1.255915528,2.152573235,-2.215126413,-3.676825005,-0.934614449,-3.457358025,-1.098720741,-1.908113846,-3.948917893,1.811703761,-3.8224451541900635,-5.396825790405273,-2.089837074279785,-1.1555471420288086,-1.5225400924682617 -2978,2978,M180T,0.054493254000000005,-0.06500485,-0.001645969,-0.024702962000000002,0.02379943,-0.027053503,-0.089290132,0.19827664,0.040511419,-0.06678012900000001,-0.06322957,0.004767404,-0.008059341999999999,-0.069831409,0.020425486,0.037038955,0.010559905,1.6669154590000002,3.6104699410000003,6.01622346,7.249510506,5.492690681,5.487993538,6.1231147,5.727807877,0.43643881799999995,5.898483477,3.5723230838775635,1.4733257293701172,6.326972961425781,4.987548828125,4.614123344421387 -2979,2979,M180W,0.015625657,-0.108573852,-0.032831947,-0.008438496,-0.152728798,0.018246246,-0.047578088,0.078829401,-0.053435027,-0.08027087299999999,-0.136876831,0.04164925,-0.10731314300000001,-0.024687286,0.007810295,-0.157597953,-0.147859643,1.326295974,2.132192502,-5.2740229,-5.866425446,-4.635393738,-7.039743561,-4.021189957,-4.807361801,-7.092650281,-4.335714809,-6.97860050201416,-10.017748832702637,-5.253077507019043,-5.177239894866943,-5.948373317718506 -2980,2980,M180V,-0.035934004,-0.073453965,-0.0005608540000000001,0.01201426,-0.080730722,-0.012497858,-0.134887684,0.063019677,0.005543353000000001,-0.048671887000000004,-0.098236042,0.024519924,-0.025641631,-0.023729635,0.047758155,-0.023238143,-0.138223301,1.412703685,2.6576615169999998,-0.339507751,-1.0944311979999999,-0.026790732999999997,0.20910425600000002,-0.19065786,-0.594763222,-4.064971312,0.503577901,-3.038742780685425,-4.848298072814941,-1.3301105499267578,-1.896350383758545,-2.5962061882019043 -2981,2981,M180Y,-0.053329242,-0.113604064,0.0046550770000000005,-0.06634654799999999,-0.195293479,0.009574324,-0.115565927,0.008907444,0.02650755,-0.157362281,-0.069845846,0.047225842999999997,-0.03791569,-0.09877155800000001,-0.033921538,-0.10713551,-0.28345144699999997,1.4709603169999999,2.357611993,-5.067096524,-5.700612961,-4.521300133,-8.284508286,-2.576757568,-4.252303673,-5.857609942000001,-0.874274455,-5.185279846191406,-8.744123458862305,-3.3438968658447266,-3.2978291511535645,-4.780210971832275 -2982,2982,P181A,-0.022723504,0.032185041,0.033034793,0.036470937,-1.419223265,0.040446662,0.028343059,-0.073790067,-0.022621112999999998,0.005747189000000001,0.058622892,0.049784104,0.016285482,0.054753095999999994,0.018188778,-1.2050703999999999,-1.633376129,0.7029418620000001,1.338779173,-5.513981544,-4.651524384,-7.087552382999999,-5.899771355,-5.55784758,-4.3732120210000005,-4.75221122,-1.098045272,-5.047956466674805,-7.863363265991211,-6.190065860748291,-8.121274948120117,-7.0229902267456055 -2983,2983,P181C,0.016975172,-0.044518649,0.017524572,-0.036252022,-1.356029739,0.084111875,-0.108180326,0.14213067,-0.060206304,-0.03174083,-0.057296467000000004,0.047859847000000004,-0.012810704,0.020191933000000002,-0.092695976,-0.880487403,-1.831572075,0.708401941,1.37035961,-11.58361113,-10.5397231,-13.96978693,-11.49255343,-11.05771031,-10.85828185,-8.354583134,-5.905761929,-11.438484191894531,-13.23927116394043,-10.512052536010742,-13.359310150146484,-12.09119987487793 -2984,2984,P181E,-0.050069249,-1.5264310030000001,-2.304448559,-2.150489505,-2.3740746130000003,0.03711098,0.023577382999999997,-0.123715881,-0.082608655,-1.5106881330000002,-1.542173873,-2.592001413,-2.016895704,-1.8181883819999998,-2.482790628,-2.397223266,-2.35092596,0.160193341,-0.9721001,-13.24538967,-12.36802357,-15.56660244,-12.78681053,-12.95973222,-12.5457796,-10.54740915,-10.48901789,-11.50787353515625,-15.39236068725586,-14.532365798950195,-13.337462425231934,-13.113286972045898 -2985,2985,P181D,0.032789424,-1.589495511,-1.9526825319999999,-2.8523284639999997,-3.1813402539999998,0.031623061,0.08090160099999999,-0.015322754,-0.101493999,-1.6390874009999998,-1.53990362,-2.039159444,-1.866205619,-2.770496392,-2.934160535,-2.9235625439999997,-3.439117964,-0.11719307,-1.0495454659999999,-13.43531346,-13.13638719,-15.67102435,-12.853008500000001,-12.5812394,-12.93490783,-10.54740915,-10.48901789,-12.363983154296875,-15.471145629882812,-15.556405067443848,-13.693453788757324,-14.588324546813965 -2986,2986,P181G,-0.015779644,-0.033697753,-0.0027786729999999997,-1.4818306780000001,-2.424367976,0.062659844,0.020584400000000003,-0.052143687,-0.031522942000000005,-0.062664225,-0.00473128,-0.010419345,0.0048619990000000005,-1.234158767,-1.7295025880000001,-2.323882254,-2.5248536980000003,1.007311317,0.763290707,-11.29686079,-10.63734967,-13.01452847,-11.50004712,-10.96436321,-10.36801546,-8.584840925,-6.048170402,-8.124483108520508,-14.062870025634766,-10.28671932220459,-12.569062232971191,-11.796111106872559 -2987,2987,P181F,-0.150897543,-1.4976213180000002,-2.122247712,-2.283333016,-3.1775116910000003,0.134045505,0.020250001,-0.32204508600000004,-0.13227855300000002,-1.5340988919999998,-1.4611437440000001,-1.8372609219999998,-2.4072345019999997,-2.267567873,-2.299098158,-2.89775528,-3.4572681010000004,0.113428037,-1.010749196,-14.611993700000001,-13.51258096,-17.35671539,-14.41161508,-13.81931097,-13.95974609,-10.54740915,-10.48901789,-13.842388153076172,-16.42894744873047,-14.044279098510742,-13.671031951904297,-16.139720916748047 -2988,2988,P181I,-0.134727095,-0.009458025,0.045668167999999995,-1.310542795,-2.435086889,0.100693126,0.001255364,-0.27070955399999996,-0.134707239,-0.060257251,0.041341202,0.075123068,0.016213267,-0.760302477,-1.8607831119999998,-1.867611139,-3.0025626389999998,1.746575183,1.413475877,-13.21137184,-11.79870509,-15.04863365,-12.29879764,-12.78133774,-14.12938509,-9.039852408,-7.164707093,-10.221385955810547,-11.612648963928223,-11.725160598754883,-10.84634017944336,-12.713787078857422 -2989,2989,P181H,-0.048541475,-1.103612453,-1.9458272140000001,-2.3420534330000002,-3.0345645880000003,0.06499383,0.003874465,-0.100957415,0.02430223,-1.075014778,-1.1322101279999999,-1.8755014490000002,-2.016152978,-2.247816454,-2.436290412,-2.525821342,-3.543307833,0.263285832,-0.67436389,-13.60648739,-12.81653651,-15.85143327,-13.19150572,-12.92064789,-13.25231357,-10.54740915,-10.48901789,-12.567462921142578,-14.872404098510742,-13.86933708190918,-12.155534744262695,-13.626175880432129 -2990,2990,P181K,-0.025928549,-1.4660399869999998,-2.003690444,-2.04595424,-3.0845306839999997,0.027155428,0.027781853999999998,-0.079638951,-0.10819102300000001,-1.6451193659999999,-1.286960607,-1.734401576,-2.272979312,-2.118951037,-1.9729574419999998,-2.669957198,-3.49910417,0.060252915,-0.933365305,-13.49401973,-12.43319302,-16.1959659,-12.829382800000001,-12.81952224,-13.19203471,-10.54740915,-10.48901789,-14.940266609191895,-18.097061157226562,-16.341480255126953,-13.553119659423828,-13.906536102294922 -2991,2991,P181M,-0.098847394,-0.028208582000000003,-0.8415631709999999,-1.790765766,-2.428427535,0.08920609800000001,0.056031599,-0.253726387,-0.117038586,-0.065682235,0.009265071,-0.672307289,-1.010819052,-1.847884265,-1.733647266,-2.6030104080000003,-2.253844661,2.0918136130000002,0.952711018,-11.44955091,-10.40187309,-13.48620638,-11.34645129,-10.89099654,-11.12222723,-8.185210046,-5.818316875,-10.982653617858887,-11.77666187286377,-12.295560836791992,-11.928396224975586,-12.68748950958252 -2992,2992,P181L,-0.131670244,-0.038127028,-0.183004558,-1.5983319480000002,-2.624131341,0.10703717,0.01461772,-0.277958208,-0.066362607,-0.055855188,-0.020398868,-0.11843617599999999,-0.24757294,-1.458884545,-1.737779351,-2.3321100009999998,-2.91615268,1.039236286,0.7402016,-10.73324673,-9.224401497,-13.28901377,-10.02836897,-10.05376411,-11.070685300000001,-7.053453554,-3.3532029469999998,-9.379048347473145,-12.46401309967041,-11.062244415283203,-10.74368667602539,-11.233038902282715 -2993,2993,P181N,-0.062651752,-0.735730008,-2.0004596969999997,-2.191598684,-2.972155468,0.065117217,-0.003002056,-0.122301447,-0.020058454,-0.6381467270000001,-0.833313289,-2.226866065,-1.7740533280000002,-2.055113026,-2.328084341,-2.907149183,-3.037161752,0.624403086,-0.49134402299999996,-11.10932125,-10.92237074,-12.75502087,-10.25473325,-10.332674,-11.28180738,-8.370642265,-5.224077195,-11.883959770202637,-15.14055347442627,-14.094522476196289,-12.567217826843262,-12.948723793029785 -2994,2994,P181Q,-0.091120447,-1.610218476,-2.10104175,-2.002870084,-2.940623847,-0.018370495,-0.058151283,-0.12408961,-0.10869562099999999,-1.6564978869999998,-1.563939065,-1.709782444,-2.492301056,-1.787906877,-2.217833291,-2.8952155389999996,-2.986032155,4.022647929,1.673105928,-11.83239411,-11.01797291,-14.29214009,-11.23801759,-11.179226400000001,-11.43461356,-9.020694037,-7.164707096,-11.39261531829834,-13.464655876159668,-13.898455619812012,-11.296445846557617,-11.533093452453613 -2995,2995,P181S,-0.038313146,-0.038317500000000004,0.007653302,-1.260847925,-2.254049517,0.053807527,-0.002173023,-0.074453269,-0.046064724,-0.06413490599999999,-0.012500094,-0.016631794,0.031938397,-0.817529147,-1.704166702,-2.122883644,-2.38521539,1.9564460069999998,1.404494832,-8.61924234,-8.131993233,-10.19503205,-9.101835182,-8.502683632,-7.164667603,-6.603327967,-3.815972448,-7.688229560852051,-10.681868553161621,-8.969273567199707,-8.974124908447266,-8.86766242980957 -2996,2996,P181R,0.004046027,-1.735702055,-2.0483717969999997,-2.299015958,-3.55518077,0.065697275,0.012324236,-0.004232183,-0.118663829,-1.895500536,-1.575903574,-2.0573334130000003,-2.039410181,-2.099460193,-2.498571722,-3.293919031,-3.816442508,0.000694101,-1.109635779,-13.11717433,-12.41906194,-14.81943009,-12.80895535,-12.73073528,-12.80768898,-10.54740915,-10.48901789,-14.846323013305664,-16.75054931640625,-14.840185165405273,-13.04591178894043,-13.652713775634766 -2997,2997,P181T,-0.031600892,0.012677177,0.017219461000000002,-0.455022181,-2.108980881,0.054766632,0.028988526,-0.09219031,-0.050446467,0.004298352,0.021056001,-0.006827567,0.041266488,-0.23867121600000002,-0.671373146,-2.016807603,-2.201154158,1.278034174,1.3245107390000002,-7.811983484,-6.2626532589999995,-8.733705687999999,-8.377271499999999,-8.188736382,-7.497550591,-6.145297457000001,-4.13882665,-8.24014663696289,-9.724411010742188,-8.205869674682617,-8.823873519897461,-9.396598815917969 -2998,2998,P181W,0.040879226,-1.559352892,-1.896963652,-2.583625217,-2.912637008,0.14106328,0.01135693,0.07040152200000001,-0.166681616,-1.723899293,-1.394806491,-2.0270613230000003,-1.76686598,-2.4573682740000002,-2.7098821589999997,-2.610434427,-3.214839589,-0.137028183,-1.129968582,-14.14468692,-13.32915636,-16.88926505,-13.66471542,-13.30778165,-13.53251613,-10.54740915,-10.48901789,-16.621183395385742,-19.34128189086914,-14.828784942626953,-16.960464477539062,-18.012237548828125 -2999,2999,P181V,-0.09007976300000001,0.006426027,-0.018369568,0.009570495,-1.1222861990000002,0.065959908,0.026661527,-0.206821053,-0.030463631,-0.048083497,0.060935551,-0.019064086,-0.01767505,0.027486447999999997,-0.008345458,-0.831464525,-1.4131078730000002,0.6156244679999999,1.3611731440000001,-10.01241568,-9.202768172999999,-11.43838967,-9.349241455,-10.35580881,-9.71587027,-7.680713474,-3.7626661710000002,-7.962969779968262,-9.632377624511719,-9.291852951049805,-9.92878246307373,-10.251436233520508 -3000,3000,P181Y,-0.001316157,-1.622208455,-2.322468686,-2.13956668,-3.051126408,0.033762493,0.068853851,-0.071486165,-0.121123472,-1.56852284,-1.6758940690000002,-1.898013809,-2.746923563,-1.976138243,-2.302995117,-2.481386913,-3.6208659030000003,0.242438345,-0.979933231,-14.57635852,-13.43875423,-17.40130486,-14.29965802,-13.72607599,-14.01599953,-10.54740915,-10.48901789,-15.063186645507812,-16.999515533447266,-15.155384063720703,-13.76015853881836,-16.220623016357422 -3001,3001,A182C,0.025894036000000002,-0.035709563,0.03173834,-0.007392236,-0.004182229,0.005275856,0.032091526,0.019696545,0.012138082,-0.076976242,0.005557116,0.02795338,0.0355233,-0.035918838,0.021134366,-0.019605707,0.011241248999999998,1.276755325,2.5206573519999997,-6.119038477,-5.739468948,-6.375403572000001,-6.63780127,-5.360942719,-6.481575874,-5.076847329,-4.590254722,-7.528805732727051,-9.891519546508789,-8.194275856018066,-7.720361232757568,-8.945690155029297 -3002,3002,A182E,-0.00959176,0.002769044,-0.018941232,-0.032108016,-0.009028851999999999,0.024502577999999997,-0.021744947999999997,0.002561429,0.026587702,-0.04068047,0.046218557,-0.01852068,-0.019361784,-0.041988405,-0.022227627000000003,-0.050964512000000003,0.032906807999999996,1.237588698,2.353131451,-0.049515779,0.344674858,-0.79551416,-0.705582497,0.5499762570000001,0.358866646,-0.908612808,-0.9205022420000001,-3.742523193359375,-4.8737335205078125,-4.5229902267456055,-5.085663318634033,-5.348698616027832 -3003,3003,A182D,-0.010321046,0.004460448,-0.038380233,-0.039691878,-0.42100508,-0.039974477,-0.018024089,-0.002618003,-0.007955333,-0.024458627,0.033379523,-0.02865837,-0.048102096,-0.030701684,-0.048682072,-0.34971380399999996,-0.492296355,1.2614721709999999,1.80289256,-1.326406583,-1.882308281,-0.986169266,-1.357856781,-1.726025696,-0.67967289,-2.252444481,-1.445026718,-5.907130241394043,-5.825862884521484,-6.338876724243164,-6.472268104553223,-6.598998069763184 -3004,3004,A182G,0.02474292,0.03109095,0.02683687,0.009605273000000001,0.037299282999999996,0.00696928,0.020250527,0.029235312000000003,0.011781208,0.018232331,0.043949569,0.026464506000000002,0.027209234,0.018020793,0.0011897519999999999,0.031112921,0.043485644000000004,1.086110299,2.62480595,-3.78876118,-3.685652123,-2.9651829989999996,-3.7363082960000003,-3.568226028,-4.988436455,-4.513010148999999,-2.079500819,-5.854675769805908,-6.543879985809326,-5.880774974822998,-5.677285671234131,-5.284164905548096 -3005,3005,A182F,-0.0042574859999999996,-0.002313163,0.006694042,0.01810184,0.01557299,0.028361985,0.011636674,-0.020151646000000002,0.012579858000000001,0.04583455,-0.050460875999999995,0.047137961,-0.033749877000000005,0.033048262,0.003155417,0.083454082,-0.052308102,1.187700577,2.9060814219999997,-5.899384666,-5.951768166,-6.107528893,-6.410334473,-4.485142113,-6.5421496889999995,-4.748530465,-3.341097594,-7.046803951263428,-7.770735740661621,-6.297305583953857,-6.487112998962402,-6.401368141174316 -3006,3006,A182I,0.028114987999999997,-0.031001179,0.00765558,-0.007619298,-0.029102077,0.051181332,0.021266757999999997,0.034963217000000005,-0.074029565,-0.053269597,-0.008732761,-0.018920706000000002,0.034231865,-0.046202227,0.030963631000000002,-0.015450191,-0.042753963,1.221686564,2.513350546,-3.07031972,-2.683047493,-3.808281799,-3.440279915,-1.897979225,-3.52201017,-2.445307402,-2.434743257,-3.790651321411133,-6.298460483551025,-5.017099380493164,-4.549295902252197,-3.6823911666870117 -3007,3007,A182H,0.006833372,0.024640912999999997,0.035440031000000004,0.0075225330000000005,0.046813930999999996,0.0035558459999999997,-0.01156469,0.025231434,-0.002397972,0.023484947000000003,0.025796878,0.034870672000000005,0.036009388999999996,0.002165945,0.01287912,0.030381787,0.063246075,1.095078236,2.6286228030000003,-3.9175884169999997,-3.30811161,-4.085450417,-4.71502243,-3.434905853,-4.044451775,-3.133706316,-2.454418826,-5.835930347442627,-5.321561336517334,-4.907805442810059,-4.648193359375,-5.010626316070557 -3008,3008,A182K,0.10665020800000001,0.017039981000000003,0.069344958,0.058207835,0.071641012,0.021031327000000002,0.077300884,0.135999532,0.019909909,-0.06839861900000001,0.102478581,0.055242747,0.083447169,0.02064001,0.095775659,0.035489328,0.107792696,1.272180895,2.764454626,-1.7681001719999998,-1.420956551,-2.213060387,-2.658405342,-0.683435997,-1.864642586,-2.532186713,-0.679861378,-5.01814603805542,-5.096246719360352,-4.92267370223999,-4.3937811851501465,-4.334240436553955 -3009,3009,A182M,0.063272862,-0.018380102,-0.025762652999999996,-0.011764165,0.02676237,0.104492139,0.116584602,0.009961121,0.051071299,-0.057193315,0.020433112,-0.061362464000000005,0.009837159,-0.015926133000000002,-0.007602195999999999,-0.022789666,0.076314406,1.281820378,2.54075862,-4.570704352,-4.386302979,-4.846672096,-4.97599807,-3.894245148,-4.750303467,-4.018196716,-3.28021597,-5.249416351318359,-7.145092487335205,-6.048074722290039,-5.1948323249816895,-4.477295398712158 -3010,3010,A182L,-0.000940848,-0.007574905,0.052682988,0.019510469,0.023923761,-0.028036942999999998,0.02475238,-0.026634075,0.007588534,0.015478001000000002,-0.030627811,0.046461632,0.058904343,0.034004837,0.005016100999999999,0.04102483,0.006822691999999999,1.2536779040000001,2.843603555,-2.790549126,-2.512883537,-3.042941605,-2.268565147,-2.126583397,-4.0017719419999995,-2.755636434,-1.088699649,-3.845921039581299,-5.278038501739502,-4.383471965789795,-4.036930084228516,-3.4290122985839844 -3011,3011,A182N,0.055181494000000005,0.029055925,0.013848575,-0.011045558,-0.025473966,0.019931853,0.06925809299999999,0.041104893999999996,-0.015353459,-0.02333283,0.081444679,-0.048063787000000004,0.075760937,-0.041857985,0.019766869,-0.036723036,-0.014224895,1.346056256,2.522759118,-1.3062665740000001,-0.925605583,-1.2738601,-2.106773369,-0.621586578,-1.60350724,-2.398780227,-1.444579874,-5.35720157623291,-4.7202630043029785,-6.232787132263184,-5.070085048675537,-4.375494003295898 -3012,3012,A182Q,0.002359254,0.08445270099999999,0.03631002,0.035223233,0.008577633000000001,0.038149821,0.010126007,-0.0054075,0.034397991,0.06317485099999999,0.10573055,0.05659220400000001,0.016027836,0.026528926,0.04391754,0.021308992000000002,-0.004153727,1.2154302959999999,2.8533437680000002,-1.8209457569999998,-1.4743611909999998,-2.05743457,-2.280425407,-1.041883675,-2.25062394,-2.7213743439999996,-1.696564811,-4.382638931274414,-5.254271507263184,-4.832884311676025,-4.1724042892456055,-4.401606559753418 -3013,3013,A182P,0.001457656,-0.02581082,0.002850225,-0.015261643,-1.656836061,-0.029733932999999997,0.014654502,-0.011739191000000001,-0.000585316,-0.023340593,-0.028281047,-0.022894422999999997,0.028594872,-0.031207267,0.0006839810000000001,-1.541237199,-1.772434923,0.7690644729999999,1.323497125,-6.62325748,-6.56815416,-6.906690308,-7.071876045,-5.447978241,-7.121588646,-5.735882589,-4.541173962,-6.8248066902160645,-8.681177139282227,-8.064750671386719,-10.070167541503906,-8.089839935302734 -3014,3014,A182S,-0.026177605,-0.03523688,0.008293303,-0.010591371,-0.006001543000000001,-0.009138009,-0.032693259,-0.019661951,-0.019298918999999998,-0.023383342,-0.047090417,0.010396806,0.006189799,0.018418045,-0.039600786,0.020346033,-0.032349117999999996,1.1336280429999999,2.7783424119999998,-2.0529901059999998,-2.421104118,-2.0598083419999997,-2.394002342,-1.015357262,-2.374678467,-2.324410797,-1.4196967969999998,-4.374087333679199,-5.088433265686035,-4.401058673858643,-4.073153018951416,-3.8377647399902344 -3015,3015,A182R,0.025848383,0.00464593,0.021281539,-0.003368994,0.020417383,0.002075713,0.030925892000000003,0.020770873000000002,-0.010317935,-0.013232296999999999,0.022524157000000003,0.012336755,0.030226322000000003,-0.010593766000000001,0.003855778,-0.002532481,0.043367246,1.212823993,2.588918956,-1.606787746,-0.928863205,-1.811418785,-2.4280829319999997,-1.085835442,-1.779738365,-1.516146613,0.519177056,-4.505147933959961,-4.851414203643799,-4.534858226776123,-2.8413710594177246,-3.573686122894287 -3016,3016,A182T,0.012578783,-0.0022448520000000003,0.031140745,0.025650758,-0.023171976,0.009294604,0.014848667,0.010308898,0.0027156520000000003,0.008608254000000001,-0.013097958,0.041812201,0.020469288000000002,0.046609433,0.004692083,-0.012757814,-0.033586137,1.156526309,2.563583434,-2.522444884,-2.611330223,-2.7438612439999996,-2.951888542,-1.6708596569999998,-2.6342847519999997,-3.0411509760000004,-2.246883451,-4.258577823638916,-5.344621658325195,-4.6398091316223145,-4.8551926612854,-4.283227920532227 -3017,3017,A182W,-0.01898659,-0.018896031,-0.000376701,-0.018677241,0.024065487000000003,-0.008680061999999999,0.037002792,-0.074975971,0.021440265,-0.09683879,0.059046728,-0.071970294,0.071216892,-0.112318617,0.074964135,-0.044631391,0.092762364,1.259706967,2.367387496,-6.386762497,-5.934479645,-6.44431575,-6.751424736000001,-5.699582747999999,-7.104009605,-5.296708265,-4.364194988,-8.56451416015625,-9.623607635498047,-7.4972662925720215,-7.719822883605957,-7.169643878936768 -3018,3018,A182V,0.013361785,0.013922575,0.01616376,-0.02134548,0.022611642,0.008248703000000001,7.159999999999999e-05,0.02665197,0.011941461,-0.006353799,0.034198948,0.013599723000000001,0.018727797,-0.015563671999999999,-0.027127288,0.000869037,0.04435424599999999,1.183886993,2.526818017,-2.094048015,-1.9810862580000002,-2.7580858760000004,-2.124738396,-1.560268433,-2.0460611109999998,-0.9828831990000001,-1.9543969280000002,-3.514927864074707,-5.500057697296143,-4.36454439163208,-4.5502519607543945,-3.880363941192627 -3019,3019,A182Y,0.003872978,-0.045122269000000007,0.01585435,0.01144438,0.039926567999999996,-0.011408198999999999,-0.022898875,0.03064483,-0.011054841000000001,-0.052772977,-0.037471561,0.01319002,0.018518679,-0.024094922,0.046983682,0.037652938,0.042200197,1.219011973,2.738503741,-4.789803189,-4.535424896,-5.09901075,-6.003264907999999,-3.1786558080000002,-5.132659584,-4.547569096,-1.662790943,-7.22292423248291,-6.8020339012146,-5.619884490966797,-5.848583221435547,-6.037405967712402 -3020,3020,A183C,-0.023740565,-0.074572573,-0.034712441000000004,0.028587076,-0.496674031,0.012805835,0.011003116,-0.058484245,0.06553355400000001,-0.024268642000000003,-0.124876504,-0.019668589,-0.049756292,0.019267825,0.037906326000000004,-0.357078711,-0.636269351,1.260685515,1.809424226,-7.844315279,-7.741622307,-7.933077751,-8.926923927,-8.00489801,-6.615054398,-6.940710673,-6.808251863,-12.348923683166504,-12.155292510986328,-10.907247543334961,-11.785523414611816,-12.824689865112305 -3021,3021,A183E,-0.072080794,0.012492863,-0.024964232000000003,0.010272526,-0.11130274400000001,-0.005970805,-0.022313125,-0.121848463,-0.009832961999999999,0.014263518999999999,0.010722207,-0.050594075,0.0006656110000000001,-0.034310701,0.054855752,-0.122446519,-0.100158969,1.318359053,2.187937015,-5.878227106000001,-5.970086739,-5.952479385,-6.762154678,-5.870847382000001,-4.835567345,-4.593363869,-1.3540050119999998,-7.531369209289551,-10.48182487487793,-6.84370756149292,-7.248639106750488,-8.385095596313477 -3022,3022,A183D,-0.050307149,-0.021346665,-0.044231979000000005,-0.029827562000000002,-1.46783653,-0.116659157,-0.017231761,-0.083382537,-0.017901732,-0.10826421300000001,0.06557088400000001,-0.07387401,-0.014589946999999999,-0.076431073,0.01677595,-1.192238584,-1.743434475,1.160131034,1.415927472,-6.399778052,-6.758212006,-6.66582428,-8.458146935,-5.678406662,-4.438300377,-4.961661067,-0.638759628,-9.156574249267578,-9.290712356567383,-7.293850421905518,-8.874611854553223,-9.15477466583252 -3023,3023,A183G,-0.031872006,0.006684963,0.000783183,0.017655141000000003,-1.016716013,0.01170527,-0.010363366,-0.053380646,-0.011716642,-0.000943303,0.014313228999999998,0.016722535,-0.01515617,-0.003360873,0.038671154,-0.744340076,-1.28909195,0.7423276259999999,1.396991794,-6.106286494,-5.870678283999999,-7.522611496000001,-5.873915527,-6.097609818,-5.166617348,-4.528649948,-2.596448566,-9.128721237182617,-7.853156089782715,-7.552283763885498,-8.408510208129883,-8.268457412719727 -3024,3024,A183F,-0.014698798999999999,-0.0005133269999999999,0.0028363859999999998,0.040355472,-0.294205693,-0.012090097,0.012583759,-0.041981356,-0.003670362,0.021331706000000002,-0.022358358999999998,0.046922878,-0.041250107,0.052859971,0.027850972999999998,-0.186838521,-0.401572865,1.4269208080000002,2.208931766,-8.013651286,-8.201744965,-7.801592529,-9.079235298,-8.343025909,-6.64265773,-6.021257791,-5.881729214,-11.315804481506348,-15.229680061340332,-12.806479454040527,-12.400678634643555,-11.674315452575684 -3025,3025,A183I,-0.087892656,0.035942818,-0.013414603999999998,-0.021887097999999997,-0.133558866,0.025184544,-0.064135072,-0.11165024,0.016256034,0.028260409,0.043625227,-0.015988105,-0.010841102,-0.004967501,-0.038806693999999996,-0.13286752,-0.134250211,1.406169601,2.276767748,-6.148597092,-4.9782590639999995,-6.663653427000001,-6.891743996000001,-7.486657944,-4.722671028,-4.973782923,-5.450722995,-10.904254913330078,-11.757623672485352,-11.000177383422852,-10.349908828735352,-10.291902542114258 -3026,3026,A183H,-0.027769589,0.029980958,0.018963983,0.07515109,-0.054851679,0.056062135,0.056747148,-0.112286325,-0.018488336,0.035074583,0.024887332,0.05868095,-0.020752985,0.057256338,0.09304584199999999,-0.038863067,-0.07084029,1.337756992,2.657346233,-6.587671126,-6.100622894,-6.888728844,-7.197893127,-6.896612762,-5.8544980010000005,-5.416575754,-5.57364442,-11.912764549255371,-14.078561782836914,-10.420500755310059,-10.679102897644043,-10.937623977661133 -3027,3027,A183K,-0.079786219,0.070580846,0.019954088999999998,0.035759714,-0.20409440899999998,0.18301646300000002,-0.013853022,-0.145719415,-0.034187436,0.090067559,0.051094132,0.032316574,0.007591604,0.06951444799999999,0.002004979,-0.140592685,-0.267596133,1.293486817,2.263247798,-6.869062679,-5.962195662999999,-6.86391848,-7.370639015,-7.243000031,-6.9055602039999995,-6.0737042379999995,-6.128698094,-11.19222354888916,-13.559952735900879,-10.49571418762207,-11.426231384277344,-11.88850212097168 -3028,3028,A183M,-0.022916669,0.025154984,-0.010412791,0.05120098,-0.051695839,0.076707174,0.001196196,-0.047029533,0.015877991,0.002706305,0.047603662000000005,-0.048172789,0.027347207000000002,0.042140684000000005,0.060261275999999996,-0.114492745,0.011101067,1.488885611,2.4301926259999997,-7.778223017999999,-7.573919891,-7.802128952,-8.486162415,-8.451562912,-6.577340919,-6.471527939,-6.348745482999999,-10.1561918258667,-11.957193374633789,-10.265715599060059,-9.509255409240723,-9.557653427124023 -3029,3029,A183L,0.004790857,0.015188071000000001,0.0011007669999999999,0.034230046,-1.5403384919999998,-0.02093112,0.043034715,-0.033453002,0.018144701000000003,-0.006663838,0.037039979,-0.015826025,0.018027559,-0.011499587,0.079959679,-1.293096792,-1.787580191,0.66413936,1.32976294,-8.379285672,-8.860889862,-8.148057724,-8.486375633,-9.509835953,-6.891269188,-6.885983322,-6.797286955,-10.726462364196777,-13.214664459228516,-10.5451078414917,-9.780441284179688,-10.388204574584961 -3030,3030,A183N,-0.010368569000000001,0.13849968699999998,0.108948948,0.065015831,-0.045816635999999994,0.13263534,0.043910236,-0.06464737400000001,-0.014408185,0.11382845400000001,0.163170919,0.136979355,0.08091854,0.058701579000000004,0.071330082,-0.037761685,-0.053871587,1.263124486,2.561599786,-7.226848824,-7.335209869,-8.30918631,-8.547865791,-6.643646317000001,-5.298335831,-5.3175541719999995,-5.931441132000001,-11.085260391235352,-11.944997787475586,-9.59523868560791,-9.925320625305176,-10.103541374206543 -3031,3031,A183Q,-0.04792725,-0.006727528000000001,-0.0054702430000000005,0.046720674000000004,0.021676400000000002,0.020411749,0.002613695,-0.09846819400000001,-0.002194047,-0.008256425,-0.00519863,0.030469296,-0.041409781,0.048577706,0.044863640999999996,0.034903667,0.008449133000000001,1.140736053,2.886318976,-5.783172508,-6.314887924,-5.959453948999999,-5.916889038,-5.36286776,-5.36176387,-4.989368692,-3.4316653039999996,-9.557062149047852,-13.24438762664795,-8.151046752929688,-9.060225486755371,-9.46101188659668 -3032,3032,A183P,-0.00692299,0.013912668000000001,-0.005354032,0.007483119,-1.311531959,0.01665132,0.01054576,-0.02439174,0.0038179309999999997,-0.01723911,0.045064445,-0.014249766,0.0035417020000000003,-0.02091119,0.035877427,-1.152182433,-1.470881485,0.8631850409999999,1.362019224,-7.664703239,-7.984884499,-7.473240112,-7.646140663,-8.298527817,-6.9207231060000005,-6.18386213,-6.558032337,-12.149532318115234,-12.737942695617676,-12.52247142791748,-11.536611557006836,-11.675834655761719 -3033,3033,A183S,0.004189247,0.020845917,0.04006587,0.052767135,0.021753513999999998,0.086922835,0.00630405,0.002074443,-0.020718484,-0.00756658,0.049258413,0.052223007,0.027908732000000002,0.034220468999999996,0.071313801,-0.004006541,0.047513569000000005,1.214737186,2.698344568,-2.80359147,-2.8087982410000003,-2.821316719,-3.653611824,-2.9006793369999997,-1.833551231,-2.4301824659999998,-2.5327454990000002,-7.088103294372559,-7.315764904022217,-6.6972761154174805,-7.0143303871154785,-6.698908805847168 -3034,3034,A183R,-0.044648701,0.034571484,0.025576052000000002,0.041527768,-0.23113567899999998,0.117625837,-0.01087788,-0.078419522,-0.040965376,0.041600222,0.027542745,0.036784646000000004,0.014367458,0.036814457,0.046241078,-0.19776836600000003,-0.264502992,1.379225858,2.133583363,-5.627004177999999,-5.356586716,-5.559105499,-5.964864937000001,-5.772650436,-5.481813301,-4.526437371,-5.114088888,-11.56709098815918,-14.813820838928223,-11.160484313964844,-11.394250869750977,-12.40970230102539 -3035,3035,A183T,0.009534147,0.022548666000000002,0.017386302,0.026470987999999997,-0.049025112999999995,0.062015333,0.0257282,-0.006659906,-0.016233941,-0.024345646000000002,0.069442977,0.043641877,-0.008869273,0.017900777,0.035041197999999996,-0.055557163,-0.042493063,1.384011385,2.5328971780000002,-4.627655847,-4.436845459,-4.38423735,-5.488062157000001,-5.17014843,-3.65898584,-4.357644843,-4.012949689,-8.614580154418945,-9.291473388671875,-7.631498336791992,-8.13079833984375,-7.533899307250977 -3036,3036,A183W,-0.0044056370000000004,0.001477268,0.018696625,0.049261263,-0.652367159,-0.022517626000000002,0.0058387890000000005,-0.014650062,-0.024290331000000002,-0.027612752,0.030567287999999998,0.029769385,0.007623865,0.032395928,0.066126597,-0.505342675,-0.799391643,0.657164259,1.425774123,-9.324683206,-9.037518616,-9.63349144,-10.18596162,-9.498445976000001,-8.267998375,-7.37028396,-7.468670416,-13.37298583984375,-16.59174156188965,-14.064558982849121,-14.235591888427734,-12.815157890319824 -3037,3037,A183V,-0.021128737999999998,0.0035350190000000004,-0.00441787,0.02467123,0.016607528,-0.013892601999999999,-0.029002046,-0.013255428999999999,0.020636236000000002,0.023558025,-0.016487987,0.031436545,-0.040272284,0.023680887,0.025661572,0.008400803,0.024814252000000002,1.008546763,2.519511482,-5.494781103999999,-5.139751915,-5.945951309,-5.907063003999999,-6.228166946,-4.252972343,-4.836063896000001,-4.851513624,-8.743746757507324,-9.344042778015137,-8.74070930480957,-8.098468780517578,-8.249082565307617 -3038,3038,A183Y,-0.089999149,-0.032048744,-0.005827854,0.030016786,-0.110270561,0.063862655,0.025528348,-0.205526645,-0.019529004,-0.035800692,-0.028296795,0.049182425999999994,-0.060838132999999996,0.104902001,-0.04486843,-0.077621385,-0.142919737,1.565538519,2.7509177719999998,-8.983895396,-8.474588554,-9.314401512,-10.04879456,-9.276488579,-7.805203774,-7.1678989589999995,-7.003888666,-12.997482299804688,-15.770086288452148,-13.11379337310791,-12.41622543334961,-11.466705322265625 -3039,3039,M184A,-0.007670949,-0.020116936000000002,0.006407441,-0.0028028140000000003,-1.6210737730000002,0.022686319,0.00023627099999999997,-0.015578169,-0.00586538,-0.070231697,0.029997825,-0.06894379,0.08175867099999999,-0.044599555,0.038993928,-1.510267403,-1.7318801430000001,0.817772387,1.328862368,-4.038409366000001,-2.821572563,-2.267180717,-4.046127434,-6.943618622000001,-4.113547493,-2.75325925,-1.76688287,-8.008536338806152,-7.3021440505981445,-5.715832710266113,-10.568069458007812,-6.512109756469727 -3040,3040,M184C,-0.020024225,-0.029760362000000002,-0.04711831599999999,-0.133387095,-1.7155351230000002,0.023287305,-0.013314856000000002,-0.026733592999999996,-0.008535606,-0.095538359,0.036017635,-0.123292216,0.029055584,-0.18323445600000002,-0.083539733,-1.8585895000000001,-1.572480745,1.2707733140000002,1.3422901740000002,-10.57965297,-10.12723325,-10.21311843,-11.12700714,-11.11027993,-10.32062612,-6.64778528,-4.1448565230000005,-10.294659614562988,-14.15201187133789,-8.700236320495605,-12.555867195129395,-9.650185585021973 -3041,3041,M184E,-0.025726777000000003,-0.538535152,-1.883190287,-2.1405338940000003,-3.163032745,-0.01911326,-0.031310591,-0.020142962,0.049525513,-0.556608357,-0.520461947,-2.005917932,-1.760462641,-2.110375725,-2.170692063,-3.0418593439999997,-3.2842061460000003,1.3449792880000002,-0.138641063,-11.82663974,-10.08517387,-11.18203423,-12.73722656,-13.23491512,-11.89384892,-8.477782357,-7.311449822,-11.690934181213379,-12.817784309387207,-8.46309757232666,-14.040658950805664,-13.813522338867188 -3042,3042,M184D,-0.022784556,-1.4611365769999998,-2.117561804,-2.373392185,-3.260115432,-0.01331702,-0.008812968000000001,-0.036756143,0.043490789,-1.81738331,-1.1048898440000001,-2.016815411,-2.218308197,-2.280974047,-2.465810322,-3.098514313,-3.4217165510000003,-0.8986693309999999,-1.084774251,-12.72151038,-11.70678309,-12.25896468,-13.55826331,-13.52048732,-12.5630535,-8.455645721,-7.311449822,-14.920555114746094,-15.572755813598633,-10.682283401489258,-14.524155616760254,-15.803736686706543 -3043,3043,M184G,-0.009993944,-0.071870612,-1.236829301,-2.288690503,-2.794416557,-0.001076434,-0.006959730999999999,-0.013028156,-0.013340952,-0.134843138,-0.008898086,-1.329074046,-1.1445845559999999,-2.365780054,-2.211600951,-2.732992243,-2.8558408710000003,0.940209545,0.09253781,-11.56411057,-10.72810131,-10.15459177,-12.20526958,-12.80588436,-11.92670584,-7.603322852000001,-6.429024149,-11.325292587280273,-12.793696403503418,-9.883332252502441,-14.288902282714844,-9.751605987548828 -3044,3044,M184F,-0.003377559,-0.072998573,0.006555256999999999,0.003948701,-0.249223794,-0.039049432,-0.028332662,0.021577545,0.015121633,-0.17123382199999998,0.025236677000000002,-0.021863146,0.03497366,-0.033017138,0.04091454,-0.247929337,-0.25051825,1.140336024,1.814768816,-8.373350099,-8.203760658,-7.4688407670000005,-10.22778327,-9.080827872999999,-6.8855379260000005,-4.6583522660000005,-2.37067667,-9.222366333007812,-11.649016380310059,-6.9229936599731445,-9.223337173461914,-9.994741439819336 -3045,3045,M184I,-0.044003885,-0.03799069,-0.021033345,-0.023959977,-0.030925581,-0.024640397,-0.081307886,-0.006699883,-0.004753877,-0.101752871,0.025771492000000003,-0.104831404,0.062764714,-0.08306746200000001,0.035147509,-0.10293785800000001,0.041086696,1.487893931,2.280312823,-2.683348854,-3.0961340560000004,-1.602787537,-2.588182571,-2.91251609,-3.217124016,-2.641580762,-1.215989802,-6.031801700592041,-5.307625770568848,-5.41101598739624,-7.651743412017822,-5.230821132659912 -3046,3046,M184H,-0.027584913,0.008232975,-0.784877343,-2.1569684209999997,-2.983621742,-0.035995858,-0.04206656,-0.013103265,0.034128337,-0.045686038,0.062151987,-0.8623063240000001,-0.707448361,-2.107441723,-2.2064951180000003,-3.071110025,-2.8961334589999996,1.9139221730000002,0.7402522779999999,-12.61571819,-11.68289847,-11.76393416,-14.61086838,-13.69763052,-11.3232594,-7.318412138999999,-5.511316138,-13.621288299560547,-16.683231353759766,-9.646435737609863,-13.816790580749512,-12.878100395202637 -3047,3047,M184K,-0.006939745,-0.21001071899999998,-1.462295766,-2.250184896,-3.088453138,-0.035299311,0.000431732,-0.014311221,-0.006877716,-0.312757247,-0.107264191,-1.606194371,-1.318397161,-2.268293015,-2.232076776,-2.988923269,-3.187983006,1.382772735,0.101620915,-11.11077219,-10.32923153,-10.69055606,-12.16669569,-11.16723736,-11.200140300000001,-8.124188417000001,-7.246977239,-14.997154235839844,-16.412151336669922,-11.915233612060547,-15.622950553894043,-14.771471977233887 -3048,3048,M184L,-0.030075035,-0.028226341000000002,-0.006117206,-0.006625001,-1.189826062,0.055857884000000003,-0.009336543000000001,-0.050813526,-0.042033468,-0.09017529099999999,0.033722609,-0.044139541,0.031905129,-0.06641414400000001,0.053164143,-0.947066346,-1.432585777,1.018525895,1.4228271719999999,-5.231478915,-3.5013105010000003,-6.823992615,-6.018652817,-3.911836884,-5.901601761,-4.071945976,-0.69792654,-7.113127708435059,-8.115643501281738,-5.0764360427856445,-5.108639717102051,-7.783705234527588 -3049,3049,M184N,-0.023103461000000002,-0.086900743,-1.345229326,-2.7798192339999996,-2.6419334709999998,0.009281224,-0.00953136,-0.036675562,-0.016386015,-0.124876011,-0.048925474000000004,-1.446220394,-1.244238258,-2.965651535,-2.593986932,-2.7831918019999997,-2.500675139,0.855042648,0.059992314000000005,-13.68347434,-13.30268517,-14.36115207,-14.4030263,-13.54781538,-12.80269277,-9.326089300000001,-9.664162641,-13.537548065185547,-13.596385955810547,-9.983160018920898,-13.241219520568848,-12.758573532104492 -3050,3050,M184Q,0.000468201,-0.00638453,-0.0026175260000000002,-1.22788001,-2.403221462,-0.015237536999999999,0.011237495,-0.010301094,0.037093219,-0.118413305,0.105644246,-0.06450740099999999,0.059272349,-1.050525125,-1.4052348940000001,-2.399544309,-2.406898615,1.1511333940000001,0.830686873,-9.331905232,-7.500102577000001,-10.04270785,-9.598024231,-10.18674187,-9.331949631,-6.468126871,-3.659458868,-11.338069915771484,-12.506568908691406,-7.994126796722412,-12.117871284484863,-11.057914733886719 -3051,3051,M184P,-0.033028056,-1.1658595379999999,-2.190393164,-2.459885108,-3.0305967480000002,0.023086796,-0.028939626,-0.037116485,0.034720581,-1.404563305,-0.9271557709999999,-2.441268109,-1.939518219,-2.404396749,-2.515373466,-2.823997007,-3.2371964889999996,-0.34054697799999994,-0.894739244,-12.56093716,-11.8125698,-11.99774866,-13.22729124,-13.44295313,-12.32412296,-9.326089300000001,-9.664162641,-14.410387992858887,-16.809677124023438,-13.651528358459473,-15.55332088470459,-14.639629364013672 -3052,3052,M184S,-0.036268838,-0.050471957000000005,-0.144130785,-1.6463386080000002,-2.6635718440000002,-0.031259726,-0.031543918,-0.040993757,-0.001026068,-0.065144434,-0.035799479,-0.20694725600000002,-0.081314314,-1.4866180580000001,-1.806059157,-2.50045297,-2.826690717,1.320393414,0.7875367659999999,-8.532345021,-7.717809944,-7.782505623,-9.483253288,-8.882892715,-8.795263535,-5.336343538,-3.508296399,-9.856966018676758,-11.39023494720459,-7.882887840270996,-11.98758602142334,-8.11557674407959 -3053,3053,M184R,-0.026353005,-0.982419905,-2.055137769,-2.383815128,-3.190159524,0.0016039370000000002,-0.021947307000000003,-0.030758702000000002,0.063149733,-1.169817145,-0.7950226640000001,-2.178434731,-1.931840807,-2.388235704,-2.379394552,-2.6580736419999997,-3.7222454060000003,0.28323706600000004,-0.715703706,-13.02766366,-12.08396581,-13.78701694,-13.48815012,-13.62352993,-12.1556555,-9.326089300000001,-9.664162641,-15.883447647094727,-17.40643310546875,-11.630664825439453,-16.95185661315918,-15.103517532348633 -3054,3054,M184T,-0.028301438999999998,-0.022840129,-0.20830825600000002,-1.775472161,-2.579511712,-0.034067697,-0.040733128,-0.015869749,0.031913636,-0.082711278,0.03703102,-0.279519236,-0.137097276,-1.80954345,-1.741400871,-2.706264963,-2.4527584609999997,1.406133536,0.7456390509999999,-7.814627203,-8.25908773,-6.546794952000001,-8.056327797,-8.676142319,-7.534783217999999,-5.65910034,-2.945930287,-8.989643096923828,-7.750506401062012,-7.042363166809082,-9.629240989685059,-7.394662380218506 -3055,3055,M184W,-0.027345065,-0.426407951,-1.856941516,-2.3239542,-2.987315471,0.07787624900000001,-0.025250714,-0.029439415,-0.034900461,-0.5141916529999999,-0.33862424799999996,-2.059732125,-1.654150906,-2.113037395,-2.534871004,-3.044521014,-2.9301099269999997,1.28670345,-0.16612846,-11.20513373,-10.83834392,-11.13614493,-11.35315315,-12.77808223,-9.919944443,-5.935094891,-4.689412066,-13.924137115478516,-16.280214309692383,-10.17579460144043,-14.959156036376953,-12.62350082397461 -3056,3056,M184V,-0.010718105,-0.003280458,0.000209717,0.018757403,-0.284368235,0.021091874,-0.003974027,-0.017462183,-0.010998272,-0.056504165999999995,0.049943250999999994,-0.052838555999999995,0.05325799,-0.018361894,0.055876699999999994,-0.301096378,-0.267640091,1.7439615119999998,2.278832726,-3.997260645,-3.6290795439999997,-3.247514778,-3.8713630219999997,-4.074196632,-5.164149246,-3.215703332,-2.117353853,-7.788424968719482,-8.301198959350586,-7.331814289093018,-9.25875473022461,-6.955264091491699 -3057,3057,M184Y,-0.041376596,-0.000320622,0.033301208,-0.005854532,-0.49620861200000005,-0.023330057,-0.047050813,-0.035702379,-0.058189134,-0.038450251,0.037809008,0.010090914,0.056511502000000005,0.002429874,-0.014138938,-0.433090529,-0.559326694,1.281431829,1.724732943,-10.32741354,-10.45575513,-8.924756996000001,-11.72473989,-11.73938422,-8.79243148,-5.635672965,-2.9022250130000002,-12.347817420959473,-14.42992877960205,-7.6980156898498535,-12.049201011657715,-10.747441291809082 -3058,3058,A185C,-0.008064639,-0.015629525,0.031268952,-0.0017766379999999999,-1.555559949,-0.022926801,-0.011571598,-0.00455768,-0.110207351,-0.029697519,-0.0015615310000000001,0.047631229000000004,0.014906675,-0.012775028999999999,0.009221754,-1.253067441,-1.858052456,0.6388492579999999,1.327233339,-6.925337575,-7.786796798999999,-7.493366028,-5.923378067000001,-5.297143753,-8.126003227,-5.859515987000001,-3.4709962410000004,-8.15921688079834,-11.600220680236816,-7.4668965339660645,-9.060134887695312,-8.317159652709961 -3059,3059,A185E,-0.004151671,-0.91591615,-2.07866261,-2.316155505,-2.788667675,-0.041549822,-0.015255826,0.006952485,0.078265061,-1.059552997,-0.7722793029999999,-2.255501176,-1.901824044,-2.74222049,-1.8900905190000001,-2.613916138,-2.963419211,0.238378602,-0.6735804129999999,-7.930037502999999,-8.338119995,-8.137184494,-7.271108673,-7.216540054,-8.687234299,-6.779089593999999,-4.659426992,-8.788427352905273,-12.205024719238281,-9.645641326904297,-10.190826416015625,-9.335383415222168 -3060,3060,A185D,-0.020693382,-1.175518417,-1.9717470940000001,-2.398618334,-2.268067522,-0.038378169,-0.02332981,-0.018056953,-0.040565306,-1.359426415,-0.991610419,-2.266579055,-1.676915132,-2.57720711,-2.2200295580000002,-2.448902759,-2.087232285,0.29706764199999997,-0.8398327259999999,-8.602338284,-9.410581772,-9.463603912,-7.737253326,-7.335609337,-9.064643074,-7.83767217,-4.939334003,-10.028582572937012,-13.147012710571289,-11.386442184448242,-10.918051719665527,-10.640486717224121 -3061,3061,A185G,-0.033608634,-0.023681149,-0.024861984,-0.045160985,-0.050523955,-0.011851243999999999,-0.047961102,-0.019256165,-0.040461599,-0.048215725,0.0008534269999999999,-0.023197419,-0.026526549,-0.047012735,-0.043309234,-0.04207960400000001,-0.058968306,1.4567241130000002,2.579772302,-5.233072729,-6.37270459,-6.846177483,-4.355751785,-3.826286987,-4.764442802,-5.8081828479999995,-1.137568871,-5.074871063232422,-7.380058765411377,-6.0764570236206055,-5.397613525390625,-5.220306873321533 -3062,3062,A185F,-0.06493873,-1.415873215,-2.236333583,-2.552280449,-2.844278657,-0.000787994,-0.02389632,-0.105981139,-0.074181464,-1.718448358,-1.113298071,-2.3915177919999997,-2.081149373,-2.048933333,-3.055627564,-2.7499327539999996,-2.938624559,0.087895735,-1.042675868,-10.71206912,-9.965279526,-11.06526134,-9.622275307,-9.313538132,-13.5939913,-7.98141515,-5.450003425,-10.022566795349121,-12.80251693725586,-9.707775115966797,-9.655989646911621,-8.677764892578125 -3063,3063,A185I,-0.053221542999999996,-0.017483213,-0.03144166,-1.630652641,-2.6149388719999997,-0.080200214,-0.05212027599999999,-0.05432280900000001,-0.018175191,0.013743452,-0.048709878,-0.020952832,-0.041930487,-1.603422493,-1.6578827880000002,-2.9522393960000004,-2.277638347,0.46976688,0.686914982,-5.499524615,-4.631050873,-5.399659584,-4.525361,-5.512922477999999,-7.428629142999999,-6.190670562999999,-2.946994895,-7.0912251472473145,-8.246781349182129,-7.450921535491943,-7.312811851501465,-6.0423078536987305 -3064,3064,A185H,-0.026853823,-1.124137082,-2.2067250869999997,-2.5622625759999997,-3.069942666,0.000257749,-0.013227433,-0.040480212,-0.078561555,-1.249742114,-0.998532049,-2.263350085,-2.150100089,-2.397886881,-2.726638271,-2.700946294,-3.438939038,0.549557098,-0.756004179,-8.51190275,-8.380955963,-8.488374382,-7.780150856000001,-7.304434746,-10.6055978,-7.814952449,-5.529414251,-11.146398544311523,-13.445724487304688,-10.598763465881348,-10.381942749023438,-10.272401809692383 -3065,3065,A185K,-0.044404121,-0.9674141409999999,-2.2243234590000003,-2.69690255,-3.172889151,-0.033649068,-0.039407315,-0.049400927000000004,0.076564537,-1.027973382,-0.906854899,-1.810187286,-2.638459631,-2.05386855,-3.33993655,-2.946753498,-3.3990248039999997,3.3291437760000004,1.293001436,-8.697672058,-8.854885094,-7.83964267,-7.523911064,-8.472442329,-10.79747913,-8.405112174,-5.710008152,-11.620271682739258,-13.091571807861328,-11.46884822845459,-11.934955596923828,-11.146305084228516 -3066,3066,A185M,-0.037122277,0.01843216,-0.49366125899999996,-2.103042371,-2.9285139730000003,0.004858197,-0.02067364,-0.053570914000000004,0.052393595999999994,-0.02263114,0.059495459,-0.47207556700000003,-0.51524695,-2.02574167,-2.180343071,-2.471468586,-3.38555936,1.51617317,0.709779293,-6.6747547,-7.433013282999999,-7.203390739,-5.989738045,-6.417787186,-6.329844246,-6.1249469439999995,-2.839616983,-7.251348972320557,-9.053191184997559,-7.312219619750977,-7.462540626525879,-5.962051868438721 -3067,3067,A185L,-0.050203683,-0.000365706,-1.1980125659999998,-2.240915612,-3.00665791,-0.030173362000000002,-0.043459405,-0.05694796,-0.032914345,-0.0035762520000000003,0.002844841,-1.247315677,-1.148709455,-2.195916279,-2.285914944,-2.927949934,-3.0853658860000004,0.867067265,0.106191403,-4.611370105,-4.678468521,-4.341564697,-3.8278066180000003,-5.005861122,-5.203149567,-3.730377582,-1.7326577580000002,-6.0827155113220215,-8.19465160369873,-7.042123794555664,-7.263220310211182,-4.127423286437988 -3068,3068,A185N,-0.049408827999999995,-0.7295918090000001,-2.07579401,-2.857723933,-2.9736308819999997,-0.027906552999999997,-0.047644932,-0.051172722999999996,-0.03410538,-0.7538780959999999,-0.705305521,-2.183909482,-1.9676785380000001,-2.9716587910000003,-2.743789075,-2.542324444,-3.40493732,0.235418999,-0.576251362,-6.39444984,-7.081490517000001,-8.409150856,-5.3934461670000005,-5.575910835,-5.512250824,-5.721806907,-2.495635276,-9.819299697875977,-11.727313041687012,-9.541245460510254,-9.439205169677734,-9.233907699584961 -3069,3069,A185Q,-0.00943856,-0.564634195,-2.091161466,-2.3965136819999997,-2.9605459119999997,-0.071781564,-0.029400352999999997,0.010523234,0.035638584,-0.6239128420000001,-0.5053555470000001,-2.207759092,-1.974563839,-2.643325883,-2.14970148,-2.691112791,-3.229979033,0.5073210029999999,-0.506561001,-7.5476817370000004,-7.036175033999999,-6.932364204,-6.854644523999999,-7.496833801,-9.418391121,-7.101597588,-5.147896147,-9.627421379089355,-11.989184379577637,-9.905765533447266,-9.70981216430664,-8.77364730834961 -3070,3070,A185P,-0.038933121,-1.028195166,-2.125714051,-2.448576657,-3.129075266,-0.011473812,-0.033977158,-0.043889084,-0.031293691,-1.163013578,-0.893376753,-2.1951049559999998,-2.056323145,-2.361826434,-2.535326879,-3.04643544,-3.2117150910000003,0.40872034799999996,-0.707009459,-10.02304055,-10.2672103,-10.45693192,-9.108223228,-9.039528069,-11.24330923,-10.00900564,-9.530625902,-11.707767486572266,-12.308782577514648,-14.476875305175781,-11.880159378051758,-11.277838706970215 -3071,3071,A185S,-0.026151157999999997,0.006481436,0.0007910069999999999,-0.007999524000000001,-0.573427357,-0.007586402,-0.031590272,-0.020712043,-0.073491689,-0.006798891,0.019761763,-0.006987066,0.008569079,-0.044126062,0.028127015,-0.448140169,-0.698714545,1.145803503,1.6440050659999998,-3.3760563489999997,-3.721343674,-4.319970116,-2.883989937,-3.2290336610000003,-2.7259443589999997,-3.8512957969999997,-2.557189153,-6.525244235992432,-7.675538063049316,-5.823952674865723,-6.9600114822387695,-6.534033298492432 -3072,3072,A185R,-0.05009581900000001,-1.2825759890000001,-2.2017165569999997,-2.42638156,-2.414795069,0.080328571,-0.050202208,-0.049989429,-0.035764395,-1.454712028,-1.11043995,-2.1857734090000003,-2.217659705,-2.382458111,-2.470305008,-2.26543477,-2.564155368,0.070988724,-0.912108004,-6.397883322,-5.622271317,-5.301867157,-6.1007225720000005,-6.572227814,-8.392327751,-6.443756131000001,-4.894628797,-11.404285430908203,-13.039000511169434,-11.011731147766113,-11.72421646118164,-10.641260147094727 -3073,3073,A185T,-0.020096463000000002,0.004536392,-0.056177994,-1.694488166,-2.386208396,-0.052809244000000005,-0.026372262999999996,-0.013820663,-0.019255994,-0.031485609,0.040558393,-0.078287711,-0.034068277,-1.6139845069999998,-1.774991824,-2.420178607,-2.352238184,0.8923665690000001,0.7077051540000001,-3.322105244,-3.646137421,-4.142583122,-2.257168938,-3.840589615,-2.724047127,-4.44948227,-1.362813681,-5.9888505935668945,-6.43479061126709,-5.522514343261719,-5.7990827560424805,-5.867079734802246 -3074,3074,A185W,-0.00907795,-1.292192313,-2.252573029,-2.886261769,-2.8666353310000003,-0.033356176,-0.011605388000000001,-0.006550511,-0.038710903,-1.4113335759999999,-1.1730510490000001,-2.300002811,-2.205143247,-3.2126908569999997,-2.55983268,-2.9594477689999996,-2.773822893,0.27502411,-0.8824514240000001,-11.56765105,-11.57636394,-11.34360201,-10.78717826,-10.17638213,-13.95472892,-10.00900564,-9.53062648,-12.737957954406738,-16.054840087890625,-11.504413604736328,-12.890670776367188,-11.874460220336914 -3075,3075,A185V,-0.065968972,0.008271694,0.0029441590000000004,-0.021148135,-1.607457871,0.018005252,-0.066515651,-0.06542229299999999,-0.046976620999999996,-0.002879092,0.019422479,0.036209932,-0.030321614,-0.036374049,-0.005922221,-1.446091781,-1.7688239609999998,0.718621735,1.325075583,-2.6568342069999997,-1.964291191,-1.653731812,-2.671388008,-3.0026322710000004,-3.9921277539999998,-3.5515066330000002,-1.019197891,-5.478727340698242,-6.227893352508545,-5.984989643096924,-5.80181884765625,-5.373648643493652 -3076,3076,A185Y,-0.070438859,-1.39081188,-2.080228795,-2.2078003059999998,-3.131419231,-0.049347728,-0.082046765,-0.058830952,-0.0018746720000000002,-1.620451249,-1.161172511,-1.9043545990000001,-2.256102991,-2.361110689,-2.0544899219999997,-3.107867601,-3.1549708610000002,-0.085751977,-0.99298802,-11.55339915,-11.13989272,-12.30900917,-10.03907424,-9.062355415,-15.21666421,-8.032344806000001,-5.02162522,-11.919535636901855,-13.829833984375,-9.621938705444336,-10.778362274169922,-9.561222076416016 -3077,3077,T186A,-0.051869976,0.045460022,0.022103353,0.019967521999999998,0.049039139,0.006832653,-0.01862022,-0.08511973099999999,0.017509642,0.048129118,0.04279092599999999,0.029332632999999997,0.014874072,0.023740781000000002,0.016194263,0.010059428,0.08801885,1.174553362,2.599651906,0.484448805,0.822616997,0.671510292,1.017834297,-0.139738098,0.050020537999999996,-1.174869371,0.172016602,-3.622617244720459,-3.6950230598449707,-2.957669734954834,-2.928945302963257,-3.7793221473693848 -3078,3078,T186C,-0.003947181,0.060716979000000004,0.021746003,0.049231988,0.066228188,0.03980164,0.045529917,-0.053424278,0.015723895,0.013609439,0.10782451800000001,0.061899265999999994,-0.01840726,-0.027223433999999998,0.125687409,-0.005087652,0.137544028,1.367594346,2.688442191,-3.574554997,-3.79519857,-3.751854324,-3.7905438769999997,-3.1352904660000003,-3.399887749,-4.85899242,-3.478068506,-7.468988418579102,-8.480766296386719,-8.208446502685547,-8.54538631439209,-9.104948043823242 -3079,3079,T186E,-0.06642825599999999,0.083985966,-0.015274966000000001,0.050377795999999996,0.062168247999999995,0.014513931,-0.050886065999999994,-0.081970445,-0.008633107,0.164421845,0.003550087,0.067833651,-0.09838358300000001,0.10358921300000001,-0.002833622,0.11213737,0.012199126000000001,1.093728841,3.008726175,0.161197,-0.338675629,0.8142782140000001,0.752693924,-0.322283356,-0.100028152,-1.8520646809999999,-0.395577875,-3.3996431827545166,-3.6823835372924805,-3.0411243438720703,-3.78639817237854,-5.1790008544921875 -3080,3080,T186D,-0.06338996200000001,0.09307471099999999,0.09015666300000001,0.029048848999999998,0.12718009800000002,-0.037177426,-0.07715901900000001,-0.049620905,0.02736536,0.10985126,0.076298162,0.108646558,0.071666767,0.121029369,-0.06293167200000001,0.16509674,0.089263455,1.047541235,3.116286293,-0.603712874,-1.476095177,0.5400757979999999,0.121780441,-1.443048759,-0.761276672,-2.480340976,-0.433399608,-5.046356201171875,-3.873486280441284,-3.9190847873687744,-4.189675331115723,-5.417059421539307 -3081,3081,T186G,-0.034743433,0.057712495999999995,0.017675864,0.044081295,0.057716959000000005,0.034046834,0.0014475929999999998,-0.070934459,-0.015302373999999999,0.029192147,0.086232845,0.025864204,0.009487523000000001,0.024008242000000003,0.064154348,0.032459925,0.082973993,1.093682069,2.713746065,-0.345775545,-0.557374542,-0.501538811,-0.295958267,-0.559746277,0.185740173,-1.6769552380000001,-0.531908604,-4.598779678344727,-4.285381317138672,-4.281135559082031,-4.178644180297852,-4.509918212890625 -3082,3082,T186F,-0.072259767,0.032396121,0.009118899,0.037443919,0.038390943999999996,0.07914307,-0.0068332259999999995,-0.137686308,0.072399927,0.040463713,0.024328528999999998,0.015884527,0.002353271,0.069378073,0.005509765,0.038915632,0.037866255,1.211466628,2.8480288560000004,-4.271186082,-4.07816922,-5.119311714,-5.451313118,-3.2802368769999997,-3.426899483,-4.152174097,-3.135975113,-7.330323219299316,-7.279810905456543,-6.898149490356445,-7.140596866607666,-7.398573398590088 -3083,3083,T186I,0.021356632,0.025422112,0.016256139,0.047038095,0.064125918,-0.02824627,0.053553192,-0.010839928,0.05087973900000001,-0.04188758,0.092731804,-0.101665393,0.134177671,-0.02838601,0.12246220000000001,-0.005916485,0.13416832,1.099551109,2.37430939,-3.5290195389999997,-3.627907455,-3.80451931,-4.358497581,-2.0174232030000003,-3.836750145,-5.146665032,-1.579001783,-4.852938175201416,-5.028621673583984,-5.165050983428955,-5.839191913604736,-5.242654800415039 -3084,3084,T186H,-0.041207175,0.034109373,0.032269542000000005,0.013930268999999999,0.078777168,0.0051162479999999995,-0.010753137,-0.071661212,-0.001585156,0.0044660590000000005,0.063752687,0.024053316,0.040485767,0.015148377,0.012712161000000001,0.039483708,0.118070627,1.105856703,2.705501758,-1.052583203,-1.112644081,-1.151012047,-0.656309639,-1.018484474,-1.324465775,-2.1373509090000002,-1.478939884,-6.138219356536865,-4.793899059295654,-5.507970809936523,-5.45605993270874,-5.679229736328125 -3085,3085,T186K,-0.102015287,0.045586778,-0.013633771999999999,0.023359638999999998,0.063526439,0.088081481,-0.083129967,-0.120900607,-0.029071411000000002,0.089896255,0.0012772999999999999,0.011802103999999999,-0.039069648,0.037241899,0.009477379000000001,0.036437058,0.09061582,0.914327247,2.593112217,0.785576387,0.78230719,0.981446442,0.7102528459999999,0.9736326679999999,0.48024279,-0.213029154,-0.411428136,-4.222801685333252,-4.444617748260498,-4.306516647338867,-5.027639865875244,-5.267189025878906 -3086,3086,T186M,0.000650066,0.02992557,0.056394089,0.043284625,0.079871209,-0.003534489,0.004061615,-0.0027614840000000002,0.026397969,-0.008897902,0.068749042,0.033328719,0.07945945900000001,0.055882826,0.030686422999999997,0.083128014,0.076614404,1.0658721709999999,2.817042518,-2.628861229,-2.314705551,-2.88108889,-3.7071386260000003,-1.49124218,-2.750130898,-3.583074401,-1.905964542,-4.956228256225586,-5.22465705871582,-5.766780376434326,-5.810596466064453,-5.986179828643799 -3087,3087,T186L,-0.065299913,0.020081622,-0.006086841,0.03090952,0.04893101,0.027334715,-0.029106494,-0.10149333199999999,0.022704417,0.01896793,0.021195314,0.011792839,-0.023966521,0.053318427,0.008500613,0.056878482,0.040983538,1.075634088,2.7277795210000004,-2.104693701,-2.2884361269999998,-2.697402138,-2.920768181,-0.377654083,-2.239207977,-3.460971288,-0.5185029870000001,-4.044671058654785,-4.008258819580078,-3.9983699321746826,-5.03778076171875,-4.657297611236572 -3088,3088,T186N,-0.071777942,0.05211263,0.08587661,0.061358267,0.079541488,-0.035514591,-0.059732470999999995,-0.083823413,-0.081263858,0.08801211099999999,0.016213149,0.162939704,0.008813516,0.132842612,-0.010126078,0.041183493,0.11789948300000001,1.054378671,2.949401794,-0.658452061,-1.3507616040000001,-0.100607605,-0.24848432199999998,-0.536696457,-1.05571032,-2.952713819,-1.01915564,-4.970294952392578,-3.6658449172973633,-4.114096641540527,-4.821582794189453,-4.721707820892334 -3089,3089,T186Q,-0.10242923,0.035523835,-0.034164405,0.025031605,0.070922127,0.048529296,-0.092377729,-0.112480731,0.031397836,0.095576858,-0.024529187999999997,0.029353077,-0.097681886,0.089860969,-0.039797759,0.111722482,0.030121772,1.172783769,3.065299393,0.544088359,0.503160233,0.9328265459999999,0.706571724,0.44226825700000005,0.135615036,-0.861570435,-0.502303855,-3.471237897872925,-3.639465093612671,-3.8549115657806396,-4.185128688812256,-4.4203033447265625 -3090,3090,T186P,-0.067149865,0.015478685,-0.002556131,0.013835222,-0.979858789,0.0031999000000000003,-0.028449991,-0.10584973800000001,0.010703568,0.017749551000000002,0.013207818999999999,0.015638425,-0.020750687,0.016293195,0.011377248999999999,-0.7353775159999999,-1.224340061,0.8131363079999999,1.412826818,-5.644749071000001,-5.372252258,-5.516104812999999,-5.763138512,-5.723278572000001,-5.848971199,-7.398013917,-7.3489893660000005,-8.503844261169434,-7.668855667114258,-9.771209716796875,-9.909114837646484,-9.632596969604492 -3091,3091,T186S,-0.052794932,0.024468739,0.008346544000000001,0.016023882,0.026542246000000002,0.046891017,-0.01644739,-0.08914247300000001,0.0018121020000000001,0.0039354609999999995,0.045002016,0.017271761,-0.000578673,0.009914256,0.022133507,-0.026285599,0.07937009,1.2222036059999999,2.4761450369999998,-0.071429585,0.034095657,0.287556595,0.043139015,-0.315808983,-0.406130211,-1.260373269,-0.78574134,-4.180207252502441,-4.217451095581055,-4.088784694671631,-3.883624315261841,-4.062347888946533 -3092,3092,T186R,-0.073916062,0.041397571,0.043679866,0.022182927,0.06997376599999999,0.17823061399999998,-0.035176676000000004,-0.112655448,-0.119131797,0.009543161,0.073251981,0.066898503,0.020461228,-0.004364529,0.048730382,0.030740937000000003,0.109206594,1.191079577,2.647570344,0.592316081,0.820371002,0.7974291459999999,0.694061943,0.625207077,0.024511237999999998,-0.665725105,0.513679868,-4.329256534576416,-5.169921875,-4.546220779418945,-5.009347438812256,-5.315991401672363 -3093,3093,T186W,-0.09062542900000001,-0.023354781,0.002000884,0.009366323000000001,0.043396619000000004,-0.046948307,-0.072996378,-0.108254479,-0.00713912,-0.065802754,0.019093193,0.009552085,-0.005550318,-0.001855962,0.020588608,0.039622217,0.04717102,1.177658364,2.682016338,-4.575853694,-4.181471771,-4.871396904,-4.8932327419999995,-4.359967758,-4.573199295,-4.890736925,-4.2068580010000005,-8.29325008392334,-8.71004867553711,-8.40018081665039,-8.421982765197754,-8.622776985168457 -3094,3094,T186V,-0.074503351,0.075607992,0.020407678999999998,0.061884914000000006,0.055647605999999995,-0.00881407,-0.055784109000000005,-0.09322259199999999,0.020132501,0.05816334099999999,0.09305264199999999,0.01586424,0.024951117999999998,0.04613934099999999,0.077630487,0.028994822000000003,0.082300389,1.043677402,2.540254647,-2.964307373,-3.1679438710000003,-2.988708252,-3.000943367,-2.301949387,-3.361991989,-4.53795547,-1.844081214,-4.054551124572754,-4.760392665863037,-4.892722129821777,-4.897974014282227,-4.730167388916016 -3095,3095,T186Y,-0.10081969800000001,0.066725468,0.037632009,0.024546971,0.077859825,0.120519686,-0.047504385999999996,-0.15413501,0.026340678,0.025261854,0.10818908199999999,0.035209061,0.040054957,0.025928157,0.023165785,0.017049813,0.138669837,1.1680682009999999,2.634443941,-3.600423315,-2.916757423,-4.68752562,-4.620640617,-2.942760658,-2.8344322589999997,-4.964998369,-2.7725822730000003,-7.571012496948242,-6.998651027679443,-6.795947074890137,-7.055594444274902,-7.517430305480957 -3096,3096,T187A,-0.00247782,0.039782501,-0.012975846000000001,-0.015191217,-0.499151566,0.021077328,-0.033023342000000004,0.028067703,0.019778847,0.069952977,0.009612024,0.014187423000000001,-0.040139115,0.007500955,-0.037883388999999996,-0.38263870899999997,-0.615664422,0.94998541,1.5898953830000002,-5.634194075,-4.914493683,-4.211839371,-8.131749725,-4.743877937,-6.169009658999999,-5.623722256000001,-1.641598925,-7.980741500854492,-7.839546203613281,-8.300433158874512,-8.867002487182617,-6.717001438140869 -3097,3097,T187C,-0.071034633,0.001795653,-0.010014803000000001,-0.093694775,-0.854236268,0.010845488,-0.06866157099999999,-0.073407695,0.0049709490000000005,-0.009984221,0.013575526000000001,-0.00540218,-0.014627425,-0.143273954,-0.044115595,-0.646480163,-1.061992373,1.5832389059999998,1.7981661830000002,-9.353331291,-8.838002022000001,-11.00442151,-10.29617422,-9.367192528,-7.26086618,-6.83266191,-2.127619604,-9.824142456054688,-10.089485168457031,-9.42715835571289,-9.934610366821289,-8.864665985107422 -3098,3098,T187E,-0.007346303,-0.023657092999999997,-0.06392933099999999,-1.530928188,-2.552683678,0.0036318170000000003,-0.076063279,0.061370673,0.071236613,-0.001711695,-0.04560249,-0.051017837,-0.076840824,-1.3625852790000001,-1.699271096,-2.476767615,-2.628599741,1.14938596,0.768007662,-12.44105987,-12.02727456,-12.56591955,-13.73394483,-11.56198572,-12.31617468,-10.52248242,-8.511017341,-11.35507869720459,-9.691418647766113,-9.073775291442871,-10.392618179321289,-9.118694305419922 -3099,3099,T187D,-0.10926971099999999,0.004138091,-0.038010397,-0.050844883,-0.08524659,-0.026128071,-0.13039948099999998,-0.088139941,0.05954527,0.065736493,-0.057460312,0.06976494,-0.145785734,0.043844296,-0.145534062,-0.017590605,-0.152902574,1.276624209,2.6737797530000003,-8.618710542,-8.200002617,-9.028312225,-9.45363208,-6.600597092,-9.811008698,-4.9164917589999995,-0.573999519,-8.529135704040527,-5.522465705871582,-4.367741584777832,-8.040124893188477,-5.408390522003174 -3100,3100,T187G,0.005888361999999999,0.028210136,0.0055505780000000005,-0.016230803999999998,-0.6913414290000001,-0.008837448000000001,-0.040428542000000005,0.05220526599999999,0.05573892,0.06085368,-0.004433408,-0.000657488,0.011758643999999999,-0.006661135,-0.025800472,-0.519989185,-0.862693672,0.810773139,1.462812543,-8.435471208,-7.984572281,-8.507582932,-9.15159565,-7.404895226,-9.128709953,-6.18495103,-1.686280785,-8.737287521362305,-8.780517578125,-8.552013397216797,-9.962156295776367,-6.484120845794678 -3101,3101,T187F,-0.045404997999999995,0.07005750599999999,0.05448183400000001,-0.016548101000000003,-1.8229373309999999,0.116017292,-0.035963318,-0.054846677999999996,-0.014904866000000001,0.100321464,0.039793548,0.10129507300000001,0.007668595,-0.050750212,0.01765401,-1.549508596,-2.096366066,0.5469332410000001,1.311451869,-11.68199432,-8.817125267,-15.0091776,-11.23387903,-14.90722314,-8.442566559,-6.008612364,-1.136603201,-11.543622970581055,-12.110344886779785,-11.237837791442871,-11.725346565246582,-11.515853881835938 -3102,3102,T187I,-0.087644625,0.06491658,-0.006978818,-0.013895846000000002,-0.578642539,0.04629445099999999,-0.095478441,-0.07981080900000001,0.018106997,0.139530144,-0.009696985,0.050453024000000006,-0.06441066,0.008609145,-0.036400837000000005,-0.34762532799999996,-0.80965975,1.958966849,2.392367641,-7.838811961,-6.309117737,-8.395758942,-9.45207238,-9.469714508,-5.56739624,-6.649019214,-0.9737358970000001,-8.339590072631836,-8.78641414642334,-10.025731086730957,-9.338479042053223,-8.093347549438477 -3103,3103,T187H,-0.070539448,0.035037287,-0.004869834,-0.06388287299999999,-2.217539756,0.078425123,-0.050767100999999995,-0.090311795,0.039321055,0.08446519400000001,-0.01439062,0.014707427,-0.024447095,-0.034762106,-0.09300364,-1.87840377,-2.556675742,0.7338122579999999,1.303687588,-10.96309934,-10.60261366,-11.87996316,-11.45931833,-12.71336178,-8.160239792,-7.538904772,-3.995165884,-11.103121757507324,-10.260793685913086,-9.146530151367188,-11.333089828491211,-9.083799362182617 -3104,3104,T187K,-0.164605587,-0.017233508,-0.76751297,-1.2202363859999998,-1.628477245,0.312785115,-0.165672651,-0.163538522,-0.19373753100000002,0.02780434,-0.06227135599999999,-0.8834916559999999,-0.6515342829999999,-1.42833731,-1.012135461,-2.1031869519999997,-1.1537675379999999,3.518192136,2.326351641,-12.34111129,-11.47459217,-13.63994494,-13.22905772,-11.66102549,-11.70093615,-10.52248242,-8.511017341,-12.11994743347168,-12.240434646606445,-12.029834747314453,-11.711414337158203,-10.472957611083984 -3105,3105,T187M,-0.03789987,0.006222499,0.00339993,-0.079470755,-0.569884531,0.16085450699999998,0.0101835,-0.08598324,0.027327036000000002,0.061815072,-0.049370075,0.039191324,-0.032391465,-0.029909602999999996,-0.129031906,-0.451277649,-0.6884914120000001,0.9590630840000001,1.574091243,-7.102944997000001,-5.07657222,-8.514319336,-9.59433474,-7.230271889,-5.099226799,-6.205544515,-1.7752006340000002,-8.631274223327637,-8.405192375183105,-10.557328224182129,-10.050616264343262,-7.745256423950195 -3106,3106,T187L,-0.014389416,0.050198374000000004,-0.0057828409999999995,-0.054315929000000006,-0.484891115,0.05040508900000001,-0.04410138,0.015322548,0.027864675,0.083755745,0.016641003,-0.018472331,0.00690665,-0.05842602400000001,-0.050205834000000005,-0.37079319299999997,-0.598989036,1.0808230559999998,1.662594168,-7.3370824720000005,-5.390972167999999,-9.141583481,-11.09317932,-6.736283051,-4.323394341,-5.621029696,1.004514833,-7.892269611358643,-8.774754524230957,-9.937320709228516,-9.150711059570312,-8.12232494354248 -3107,3107,T187N,0.146835362,0.067705494,0.030860622,0.04392771,-0.067171304,0.01446211,0.12653248,0.167138244,0.10173535199999999,-0.061136743,0.196547731,-0.101527436,0.163248679,-0.08995460699999999,0.177810026,-0.09348431,-0.040858297,1.486246105,2.372658463,-6.31453383,-5.43627301,-8.000293448999999,-7.456643173,-5.591130432000001,-5.088329086,-4.7259367910000005,-1.190166687,-6.63896369934082,-4.2141218185424805,-4.348890781402588,-5.826486587524414,-3.8105392456054688 -3108,3108,T187Q,-0.057097797,0.045594699,-0.011872908,-0.12052163699999999,-1.690890002,0.106282974,-0.091896611,-0.022298982000000002,0.024193715,0.080893827,0.01029557,-0.01926124,-0.004484575,-0.168101385,-0.072941888,-1.569949756,-1.8118302480000001,1.197762193,1.3667518419999998,-11.045627,-10.65344155,-11.32566238,-13.50242733,-10.0721,-9.674503716,-8.349604386000001,-5.174145708,-10.338607788085938,-10.064481735229492,-10.145782470703125,-11.106678009033203,-8.517569541931152 -3109,3109,T187P,-0.0011750719999999999,-1.0509076290000001,-1.9507857219999998,-2.039223573,-2.552642805,-0.05313572900000001,-0.039772043,0.037421899,0.071267539,-1.2169520459999998,-0.884863211,-1.955434493,-1.94613695,-2.0198811819999998,-2.058565963,-2.67245443,-2.43283118,-0.12431906599999999,-0.752173615,-12.38872204,-11.650742300000001,-12.59283674,-13.80863772,-11.78758199,-12.10381147,-10.27555753,-7.5294009289999995,-13.188858032226562,-11.819887161254883,-11.459206581115723,-14.051254272460938,-12.404017448425293 -3110,3110,T187S,-0.033943102999999995,0.040858867,-7.38e-05,-0.027495826,-0.072998047,-0.014013936999999999,-0.061315972,-0.006570234,0.068185862,0.078998424,0.00271931,0.003616989,-0.003764528,-0.007224626,-0.047767026,-0.030307517000000003,-0.115688576,1.264820319,2.529098747,-2.8905233310000003,-1.989547256,-3.829096619,-3.81862928,-2.182986305,-2.6323571930000003,-3.757538335,-0.36771381299999994,-5.223361968994141,-5.948302268981934,-4.412489891052246,-6.548725605010986,-4.757941246032715 -3111,3111,T187R,-0.091547208,0.092933389,-0.854442922,-1.548821226,-1.94747267,0.37488457700000005,-0.095000715,-0.088093701,-0.117813686,0.15228741099999998,0.033579366,-0.7866649290000001,-0.9222209140000001,-1.429797124,-1.667845328,-1.8827980180000001,-2.012147321,3.6847991789999996,2.590349861,-12.58155176,-12.47559785,-12.19292096,-15.21236257,-12.16538672,-10.86149071,-10.48853256,-8.361566337000001,-12.093982696533203,-12.681735038757324,-12.066518783569336,-11.893678665161133,-10.600831985473633 -3112,3112,T187W,-0.01087169,0.117279266,0.047987627000000005,-0.7692824559999999,-2.333350456,0.250103139,-0.021242057999999998,-0.000501321,-0.11328488800000001,0.161086237,0.07347229400000001,0.059920006,0.036055247,-0.45248970899999996,-1.086075203,-1.9501609969999998,-2.716539915,1.5990590530000002,1.379448433,-13.98684379,-12.33460432,-16.64228416,-13.98215629,-14.709030499999999,-12.26614365,-8.336045424,-4.891284924,-14.053415298461914,-14.404558181762695,-13.114853858947754,-13.756123542785645,-13.971118927001953 -3113,3113,T187V,-0.023786055,0.023386524,-0.001549652,-0.034999675,-0.670291875,0.001823534,-0.054522199,0.0069500890000000004,0.057510723,0.031851847999999995,0.014921200000000003,0.009326257,-0.01242556,-0.032733637,-0.037265713,-0.47811161399999996,-0.862472136,1.152846942,1.6452441530000002,-7.383042337000001,-5.052011406,-7.0058119660000004,-8.829811539,-8.241655693,-7.785921082000001,-6.647229316000001,-1.533883139,-8.048582077026367,-8.979196548461914,-8.954123497009277,-8.428531646728516,-8.297987937927246 -3114,3114,T187Y,-0.048593952,0.135146638,-0.057504944,-1.500922422,-2.4306478190000003,0.252472354,-0.00845919,-0.088728713,0.001082879,0.156076697,0.114216579,-0.056365277000000005,-0.058644611,-1.171086238,-1.830758605,-2.447995873,-2.413299764,0.8825504000000001,0.754023055,-14.32132197,-13.32496182,-16.86227638,-13.29797762,-16.16295296,-11.95844106,-7.684766806,-2.7667683010000004,-12.21902084350586,-11.996070861816406,-10.415816307067871,-11.64148998260498,-11.409114837646484 -3115,3115,L188A,-0.020518577,-0.052350189000000005,-0.05527152,-0.062904802,-1.20747049,-0.075153104,-0.046622712000000004,0.005585559,-0.0061199159999999996,-0.060093618,-0.044606759,-0.059171514,-0.051371525,-0.09271222400000001,-0.033097378999999996,-0.877754209,-1.537186771,1.175719652,1.485322417,-8.627420511,-8.663883156,-8.856683136000001,-8.760536392,-6.8990741810000005,-9.95692569,-6.195895843,-4.5716489110000005,-6.484360218048096,-7.787110328674316,-9.660401344299316,-9.888928413391113,-7.670408248901367 -3116,3116,L188C,0.021918244,-0.052956088,-0.026166817999999998,-0.005878016999999999,-1.090092962,-0.096717444,0.019482641000000002,0.024353846000000002,-0.00494145,-0.121542452,0.015630276999999998,-0.045804252000000004,-0.006529383000000001,-0.059718766,0.047962733,-0.891695129,-1.288490795,0.9311351609999999,1.41377584,-10.08544011,-10.94043574,-9.791555687,-11.53817464,-9.051717506000001,-9.105316993999999,-7.458772022000001,-5.984954223,-9.234809875488281,-10.839571952819824,-11.398741722106934,-12.388351440429688,-10.362029075622559 -3117,3117,L188E,-0.022292077,-0.337516945,-1.580114639,-2.3959931340000002,-3.037699413,-0.070355423,-0.025349952000000002,-0.019234201,0.013105023,-0.24272991600000002,-0.43230397299999995,-1.500183244,-1.660046034,-2.3911109109999997,-2.400875357,-3.033144902,-3.0422539239999997,1.2242249920000001,0.098449606,-12.59703572,-12.99192192,-13.12778668,-12.95171986,-11.37201019,-12.54173992,-9.916627407,-10.2655079,-12.462516784667969,-12.66159439086914,-13.60786247253418,-14.842975616455078,-13.68655776977539 -3118,3118,L188D,0.018427904,-0.725098006,-1.965789216,-2.222618055,-2.713809337,-0.116255625,0.000604229,0.036251579,0.066058042,-0.634352802,-0.81584321,-2.192836126,-1.738742305,-2.20870253,-2.23653358,-2.549706526,-2.877912147,0.562929814,-0.504970305,-12.94877676,-13.50833361,-13.31924121,-13.49938637,-11.54755515,-12.86936745,-9.916627407,-10.2655079,-13.032828330993652,-12.96340274810791,-16.470172882080078,-17.637155532836914,-16.28957176208496 -3119,3119,L188G,0.004024969000000001,-0.027412995,-0.011802058,-1.4364275659999999,-2.153407982,-0.086507109,-0.010374028,0.018423966,0.01773789,-0.019159186,-0.035666803,-0.018737619,-0.004866496,-1.321027287,-1.551827844,-2.127481734,-2.17933423,0.774853537,0.725128787,-11.69772429,-12.84238483,-11.6938976,-12.25401973,-10.367368800000001,-11.33095048,-8.432711413,-6.6496991560000005,-10.221002578735352,-12.195344924926758,-13.91108512878418,-14.394587516784668,-11.048704147338867 -3120,3120,L188F,-0.046343314000000004,-0.080928885,-0.10571058,-0.05404149,-0.129732593,-0.083994914,-0.0755392,-0.017147427,0.062353263,-0.074197938,-0.087659832,-0.06597600099999999,-0.145445159,-0.08463530400000001,-0.023447675,-0.10275339900000001,-0.156711786,1.364145129,2.229929175,-7.138384087,-7.616309631,-5.880091156000001,-9.047303154,-5.896759529,-7.251456963,-5.6083372879999995,-2.217248718,-6.9069671630859375,-7.682466983795166,-7.250131607055664,-7.638745307922363,-8.431977272033691 -3121,3121,L188I,0.021721432000000002,0.022037183,0.017778982,0.048551418,0.057770815,-0.152550278,0.019313402,0.024129462,0.071580379,0.09205545,-0.047981085,0.13687119,-0.10131322699999999,0.140659475,-0.043556639,0.130392401,-0.014850772,1.090017585,3.0145197789999996,-4.277052489,-4.38802327,-4.582082993,-4.833239021,-2.723001907,-4.858915253,-4.782911362,-3.160726838,-5.144000053405762,-6.843163013458252,-6.983801364898682,-6.804605007171631,-7.664408206939697 -3122,3122,L188H,0.058826245,-0.055225607999999995,-0.017755378999999998,-1.662675485,-2.357136858,-0.098123852,0.057282176,0.060370314,-0.044102068,-0.026969915,-0.0834813,-0.005758246999999999,-0.029752511000000002,-1.643723491,-1.681627479,-2.160818746,-2.553454969,0.963682736,0.712865124,-11.74983114,-10.83752493,-11.60532037,-13.25999049,-10.777579699999999,-12.26874023,-8.058000501,-6.605246233,-11.88137435913086,-12.427816390991211,-13.377151489257812,-13.943660736083984,-14.009307861328125 -3123,3123,L188K,-0.001801911,-0.644136855,-1.716633939,-2.274492774,-2.552699689,-0.140854673,-0.064246204,0.060642383,-0.096054253,-0.699078132,-0.589195578,-2.0467080909999997,-1.386559787,-2.36360449,-2.185381057,-2.40357849,-2.7018208880000003,1.608030166,-0.087844622,-12.45666786,-12.91355421,-12.84788934,-13.00431638,-10.77449552,-12.74308385,-9.916627407,-10.2655079,-14.635632514953613,-16.00255584716797,-17.88747787475586,-14.880376815795898,-17.1036376953125 -3124,3124,L188M,0.030134035,0.037080838,0.02556723,0.031242474,0.013036622,0.173557643,0.028108512999999998,0.032159556,-0.011581777,0.065467926,0.008693749,0.017676482,0.033457978,0.01589654,0.046588408,0.017735036000000003,0.008338207,1.212035903,2.698347019,-3.8391984860000004,-3.504306038,-3.545502739,-4.986957878,-3.594585266,-3.5646405110000003,-3.579982452,-2.04499402,-5.159950256347656,-6.1211113929748535,-6.692195892333984,-6.438956260681152,-6.2007646560668945 -3125,3125,L188N,0.076311861,0.079064491,-0.519759545,-1.7922252730000001,-2.2209471869999997,-0.29053747,0.050030263,0.102593459,-0.071102186,0.174533065,-0.016404084,-0.51779139,-0.5217276989999999,-1.948631142,-1.635819404,-1.988605142,-2.453289231,3.426463347,2.1907539519999997,-11.74352516,-12.58189905,-11.66700979,-12.91844707,-10.62159679,-10.92867307,-7.983485018,-6.731979184,-11.616935729980469,-12.418253898620605,-13.984160423278809,-14.519241333007812,-14.098250389099121 -3126,3126,L188Q,0.002275617,-0.058223163,-0.323303452,-1.776922785,-2.796089769,-0.156741203,0.001982734,0.002568499,0.054664137,-0.06574181700000001,-0.050704507999999995,-0.33260261399999996,-0.31400429,-1.94112154,-1.61272403,-2.82619358,-2.765985958,1.409330674,0.7164802440000001,-11.87106411,-12.56353465,-12.18360018,-12.22432749,-10.23496996,-12.14888824,-9.871206654,-9.953681979,-10.584465980529785,-11.843463897705078,-12.719728469848633,-12.348512649536133,-12.730215072631836 -3127,3127,L188P,-0.008176471999999999,-1.330026782,-2.184384119,-2.504880619,-2.85520948,-0.068645738,-0.033965316,0.017612372,0.063524615,-1.5868282519999999,-1.0732253109999998,-2.159686701,-2.209081536,-2.318975247,-2.69078599,-2.679284398,-3.031134562,-0.53150622,-1.018168713,-11.32190251,-11.66167559,-11.90596698,-12.19796056,-9.865851921,-10.97805747,-9.16732865,-8.426016059,-15.096163749694824,-12.65582275390625,-16.56822967529297,-12.816670417785645,-12.980756759643555 -3128,3128,L188S,0.030988929,-0.054324574,-0.048228195999999994,-0.200926457,-1.805171884,-0.162694057,0.00800728,0.053970577,0.01969241,-0.068205367,-0.040443781,-0.068000806,-0.028455585,-0.235134884,-0.16671803,-1.803739959,-1.806603809,1.253373888,1.34711866,-10.08657208,-10.71719389,-10.30387226,-11.6769986,-8.596399765,-9.138395905,-7.354691946,-5.144556167,-9.537947654724121,-11.104755401611328,-11.860774993896484,-12.51208782196045,-10.756729125976562 -3129,3129,L188R,-0.006223495999999999,-1.365831231,-2.174752305,-2.536338651,-2.954465915,-0.093969237,-0.030050752000000003,0.01760376,0.054898559000000006,-1.595067779,-1.136594683,-2.227598233,-2.1219063769999997,-2.3226458819999998,-2.75003142,-2.760559891,-3.1483719389999996,-0.68783752,-1.025059173,-12.20531454,-12.96899566,-12.20203719,-12.636119,-10.76133637,-12.45808447,-9.916627407,-10.2655079,-14.097373962402344,-15.521004676818848,-17.251049041748047,-14.852636337280273,-16.948654174804688 -3130,3130,L188T,0.035537495,-0.034539709,-0.031612913,-0.033241597000000005,-0.29830189100000004,-0.048583855,0.046285312,0.024789677000000003,0.034205156,-0.025537945,-0.043541473,-0.042607992000000004,-0.020617833000000002,-0.059374487999999996,-0.007108705999999999,-0.267847774,-0.328756008,1.4599025630000002,2.069588987,-8.715158913,-8.939680237000001,-9.228401092999999,-9.245671318,-6.994047455,-9.167994461000001,-6.558231144,-4.640139284,-7.0211262702941895,-8.799847602844238,-10.348970413208008,-10.178349494934082,-8.531844139099121 -3131,3131,L188W,-0.005505665999999999,0.0010837169999999999,0.021869237000000003,-1.2381610090000001,-1.912952574,-0.106983638,-0.03930288,0.028291549,0.037691244,0.008379983,-0.00621255,0.017946902,0.025791571,-1.008889635,-1.467432382,-1.983362087,-1.842543061,2.25388802,1.567719347,-8.049796152,-7.6176235729999995,-7.997799614,-9.967349876,-6.905369385,-7.76083831,-6.204658488,-4.490488647,-9.830105781555176,-10.998052597045898,-10.998590469360352,-11.087822914123535,-13.730222702026367 -3132,3132,L188V,0.021504185,-0.025040412,-0.046188727,-0.030946418,-0.081581387,-0.063368251,-0.025193864,0.068202234,0.007415074000000001,-0.0465887,-0.0034921229999999998,-0.073721825,-0.018655629,-0.098037803,0.036144968,-0.10239730400000001,-0.060765469,1.3617598480000002,2.235593191,-5.332364012,-5.543175827000001,-5.140654068,-5.789023201,-4.268513283,-5.920453682000001,-5.755182501,-2.9179900919999997,-5.185806751251221,-6.5059638023376465,-8.163553237915039,-7.657692909240723,-7.122258186340332 -3133,3133,L188Y,-0.058809655999999995,0.013988469,0.016992074,-0.024781799,-1.120273917,-0.046393262000000005,-0.112965698,-0.004653613,0.176668238,-0.01717766,0.045154598,0.052512005,-0.018527857,-0.050088782000000005,0.000525184,-0.8247483390000001,-1.415799494,0.766689025,1.3871123380000001,-9.338633989,-8.737391167,-7.995724747000001,-11.57245286,-8.770836037,-9.616765137,-4.969438372,-2.29874559,-7.269854545593262,-8.744905471801758,-9.6708984375,-10.118738174438477,-10.825630187988281 -3134,3134,R189A,0.022913215,-0.019845914,0.014606148000000001,-0.020606068,-0.017229056,-0.051370195,0.010717579,0.03510885,0.028612883999999998,-0.029198183,-0.010493644,0.032562334,-0.0033500390000000004,-0.033521329,-0.007690806,-0.009867948,-0.024590162999999998,1.323844396,2.642309041,-3.931520349,-4.95875351,-3.0290880889999996,-3.723505119,-3.328450974,-4.617804054,-4.923875324,-0.415841034,-5.768575668334961,-6.479903697967529,-4.328758716583252,-6.22059440612793,-5.041213035583496 -3135,3135,R189C,0.078814877,0.0015941520000000002,0.020839035,0.012955113999999998,-0.003296714,-0.096298044,0.090781446,0.066848308,0.020112668,-0.027823237,0.031011541,0.013553262,0.028124807999999998,-0.017634155,0.043544383,-0.000220234,-0.006373194,1.1691247679999999,2.573707615,-8.228251372999999,-9.019602577,-8.184463356,-6.7973975520000005,-9.041738205,-8.098055176,-7.501274445,-4.73699917,-8.637720108032227,-10.82801628112793,-7.102755546569824,-9.621969223022461,-6.436902046203613 -3136,3136,R189E,-0.0073795959999999996,0.000276437,-0.0009229039999999999,0.004874544000000001,-0.303910933,-0.078782972,-0.014978658999999998,0.00021946700000000002,0.076141275,-0.026325822000000002,0.026878696,-0.012173231000000001,0.010327423,0.017952239,-0.008203152,-0.247869118,-0.359952747,1.16112586,1.8608409719999999,-2.3188110180000003,-2.49918364,-2.254430847,-1.320054329,-3.5605466310000002,-1.959839645,-3.7062587939999996,-0.219645669,-5.321578025817871,-6.842250347137451,-3.7254202365875244,-6.528247833251953,-4.0864667892456055 -3137,3137,R189D,-0.011796437,-0.056782793,-0.040873402,-0.039571741,-1.147991783,-0.134423248,-0.046501191,0.022908317,0.022928387999999997,-0.071921271,-0.041644314,-0.023698278,-0.058048525999999996,-0.08223111400000001,0.003087633,-0.786578036,-1.5094055290000001,1.021315688,1.452288201,-3.589498279,-3.22622287,-3.5285172730000003,-2.489105301,-4.577162003,-4.126483948,-4.4363656680000005,-1.875344046,-7.135238170623779,-8.372662544250488,-4.947183609008789,-8.757868766784668,-5.590889930725098 -3138,3138,R189G,0.027454466,-0.011249161,0.005039355,-0.0032351690000000004,-0.047906629000000006,-0.083224907,0.017991669,0.036917262,0.029327327,-0.035870207,0.013371886000000001,0.019596231000000002,-0.009517521999999999,-0.019499416999999998,0.01302908,-0.052334860999999996,-0.043478397,1.3479277530000002,2.52259184,-3.647680479,-4.4452390369999994,-2.129972816,-4.136704422,-4.171114182,-3.355371941,-4.0960194130000005,-1.668978148,-5.728961944580078,-6.485962390899658,-4.39717435836792,-6.6249189376831055,-4.604527473449707 -3139,3139,R189F,0.057231551,0.034031176,0.068291801,0.028687159,0.034164252,-0.09430800199999999,0.030692161000000003,0.083770941,0.042186858,-0.0006721489999999999,0.06873450099999999,0.09515567300000001,0.041427927999999996,0.084024346,-0.026650029,0.04400315,0.024325354,1.107605496,2.785883252,-8.780333279,-10.46347237,-8.304324829,-6.398182082999999,-8.002809303,-10.73287782,-7.379134872000001,-4.604622404,-8.682628631591797,-11.1204195022583,-6.62753963470459,-10.279632568359375,-7.207498550415039 -3140,3140,R189I,-0.012396398000000001,-0.0016488579999999998,-0.0369291,-0.001477996,-1.078739255,-0.083964217,-0.037666793999999997,0.012873998000000001,0.0067064559999999995,-0.034132711,0.030834995,-0.010018581,-0.063839619,-0.013159239,0.010203248,-0.8528192290000001,-1.30465928,0.630413013,1.369631712,-8.738645613,-10.87568135,-8.50214534,-7.223305679,-8.093512413,-8.998583282,-7.171284253,-3.275832991,-7.771581649780273,-9.834000587463379,-6.7591376304626465,-9.269475936889648,-6.474937438964844 -3141,3141,R189H,0.062862684,0.00376831,0.022097897000000002,-0.00076256,0.028994949,-0.089242473,0.052394487000000003,0.07333088,0.062336130999999996,0.004993428,0.002543191,0.02891534,0.015280453000000001,-0.012053987,0.010528866999999999,0.018319629,0.039670268,1.189076917,2.640709113,-1.28419646,-1.107344467,-1.593092239,-1.12446067,-0.683609589,-1.912475334,-2.536985322,-1.9920540780000002,-5.171924591064453,-5.269199848175049,-3.608283281326294,-5.197149276733398,-1.5739502906799316 -3142,3142,R189K,-0.014139725,-0.095491851,0.056788633,0.047192499000000006,0.043095827,-0.038630584,-0.040698343,0.012418894,-0.010063755,-0.041819538999999996,-0.14916416300000002,0.165698448,-0.052121183,0.068810425,0.025574573,0.130410561,-0.044218907,1.107384667,2.9304942339999998,-3.028105875,-3.971506363,-3.045740662,-2.451450752,-2.803053795,-2.868777802,-4.513367825,-0.745441358,-4.399652481079102,-3.1473093032836914,-3.62616229057312,-4.270800590515137,-2.7692813873291016 -3143,3143,R189M,0.025213489,-0.035412455,-0.008399852,-0.01574027,0.023547909,0.010953735,0.003277383,0.047149595,0.103210938,-0.066014348,-0.004810562,0.027653874,-0.044453577,0.031946647,-0.063427187,0.08429917,-0.037203352,1.0834987409999999,2.851156773,-8.903250528,-10.10188995,-8.435840111000001,-7.52246656,-9.086401131,-9.369654884,-6.560797542,-4.072348863999999,-7.657495021820068,-8.779994010925293,-6.354101657867432,-8.34278392791748,-6.223557472229004 -3144,3144,R189L,0.039392461000000004,-0.020381434,0.004636895,-0.013295572,-0.020162666,-0.11593555400000001,0.013405624,0.065379298,0.054046329000000004,-0.028537327,-0.01222554,0.009692174,-0.000418384,-0.035993594,0.009402451,-0.004823205,-0.035502126,0.978053416,2.399313709,-8.010846902,-9.612922928,-7.479939247000001,-6.44412664,-8.485814766,-8.031430931000001,-6.018101881000001,-2.5959728230000003,-6.594264984130859,-8.475748062133789,-5.374323844909668,-8.196657180786133,-5.107615947723389 -3145,3145,R189N,0.047490995999999994,-0.023471844,0.025487403,-0.110464545,-0.151627343,-0.074115839,0.033495698,0.061486293,0.12970863900000001,-0.015007196,-0.031936491000000004,0.056528202,-0.005553397,-0.060123302999999996,-0.160805786,-0.211230015,-0.09202467,1.3815607030000001,2.056764385,-3.279822583,-3.1461555860000003,-4.47727977,-2.4937665630000003,-2.560272842,-3.7216381530000002,-4.196688943,-2.085489161,-5.776077747344971,-5.3964433670043945,-4.177239894866943,-5.778104305267334,-2.559746742248535 -3146,3146,R189Q,-0.007294685,-0.008469168000000001,0.016089434,0.006403879,-0.002750312,0.045376077,-0.013983229,-0.00060614,0.1833259,0.10443331199999999,-0.12137164800000001,0.104409615,-0.072230748,0.090523707,-0.07771595,0.035566676,-0.041067299,1.543610422,3.106887046,-1.239628874,-1.661118706,-1.1917691959999999,-0.303437935,-1.711987938,-1.329830597,-2.834561775,-0.505662056,-3.632233142852783,-3.57765531539917,-2.965283155441284,-3.4072306156158447,-0.9132189154624939 -3147,3147,R189P,0.025602858,-0.026666004,-0.694758416,-1.840275487,-2.171437555,-0.078551041,0.022659277999999998,0.028546437,0.03696397,-0.044147067000000005,-0.00918494,-0.630869773,-0.7586470590000001,-1.9109861890000002,-1.769564785,-2.186467985,-2.156407125,3.080772019,1.80421002,-10.1447918,-10.98275433,-9.73491716,-9.564907532000001,-10.23873639,-10.20264357,-9.362421619,-8.092063116,-8.987688064575195,-11.709569931030273,-9.814794540405273,-10.532243728637695,-7.458545207977295 -3148,3148,R189S,0.025602035,-0.037027944,-0.011408995,-0.029251264,-0.039930577,-0.079979839,0.020008243999999998,0.031195825,0.046147889000000004,-0.053011097,-0.02104479,-0.026802954,0.0039849640000000006,-0.070728498,0.01222597,-0.023401961000000002,-0.056459193,1.372052346,2.555496231,-4.382848163,-5.352790283,-3.6197654189999997,-4.23592218,-3.8962125089999997,-4.809550423,-4.770054274,-1.6184139180000001,-5.401816368103027,-6.14996862411499,-4.518768787384033,-5.879127502441406,-4.065816879272461 -3149,3149,R189T,0.024339398999999998,-0.014084962,-0.031068516,-0.015227365,-0.14586111300000001,-0.092432266,0.016677793,0.032001004,0.029558103999999998,-0.020310003,-0.007859921,-0.033220341,-0.028916691,-0.051340929,0.0208862,-0.147006084,-0.144716141,1.446717983,2.2408187219999998,-5.305592595,-6.8947660829999995,-4.877355072,-4.841380341,-4.899679291,-5.014782188,-4.884648673,-1.586938534,-5.816635608673096,-7.053260803222656,-4.8152923583984375,-6.493453025817871,-4.731723308563232 -3150,3150,R189W,0.027951349,-0.048304976,0.021896105,-0.004475476,0.037155394,-0.033956169,0.03102118,0.024881517000000002,0.10126373300000001,-0.081443202,-0.01516675,0.052842872,-0.009050662,-0.067326212,0.05837526,-0.015034084,0.08934487099999999,1.160699455,2.310883681,-8.983569702,-9.129856041,-10.24698942,-7.15780481,-8.672057785,-9.711140457,-7.534908913,-5.4617895999999995,-8.818636894226074,-11.087525367736816,-7.3238396644592285,-9.91907787322998,-6.7524895668029785 -3151,3151,R189V,0.017249786,-0.004532015,-0.021470896,-0.020956172,-0.162167656,-0.097538691,-0.000909202,0.035408774,0.097371881,-0.031276592,0.022212562,-0.024458642000000003,-0.018483149,-0.060147937,0.018235593,-0.15627320000000003,-0.16806211199999999,1.338312844,2.131367392,-7.680897582999999,-9.525529778,-7.750949768,-6.551226051,-7.29980954,-7.276972777999999,-7.286696524,-2.304073754,-7.076537609100342,-9.186860084533691,-6.158097267150879,-8.484724998474121,-6.225883483886719 -3152,3152,R189Y,-0.005833714,-0.040701081,-0.06650236400000001,-0.058099121,-0.009767181,-0.080644685,-0.002289672,-0.009377756,-0.090665426,-0.105438385,0.024036224,-0.09091240800000001,-0.042092319,-0.089733841,-0.0264644,-0.025884032999999997,0.006349672,1.311321958,2.476381603,-5.440068082000001,-5.60817038,-5.616003227,-3.742688858,-4.940997696,-7.2924802479999995,-5.0504218430000005,-2.842339122,-7.46289587020874,-8.685859680175781,-4.73558235168457,-8.41147518157959,-4.809014797210693 -3153,3153,K190A,0.051136055,0.018567251,0.046552289000000004,0.114627695,0.131802291,-0.07971932400000001,0.075854083,0.026418026,0.165095875,0.041679545,-0.004545044,0.071827673,0.021276905,0.169760503,0.059494887,0.248097525,0.015507056000000002,0.999647928,3.1242593039999997,-2.626431894,-1.599060783,-3.3776943360000002,-3.3926156689999996,-2.597986038,-2.1648026430000002,-2.8779261689999998,0.052349634000000006,-6.108372211456299,-5.124107360839844,-6.377972602844238,-6.947249889373779,-5.8661675453186035 -3154,3154,K190C,0.070959461,0.016238781,0.021940961000000002,0.08909844800000001,0.09068624199999999,-0.116190815,0.043757902,0.098161019,0.10760317400000001,0.027743767000000003,0.004733794,0.026721788,0.017160134,0.162300391,0.015896504,0.207180058,-0.025807575,0.957748142,2.90986283,-7.221659456,-6.842708954,-7.566843177999999,-7.711919303999999,-7.469255187999999,-6.517570656,-6.9852702529999995,-4.819136913,-9.694315910339355,-9.753560066223145,-10.355940818786621,-11.081026077270508,-9.904739379882812 -3155,3155,K190E,0.058327508,0.037203692999999996,0.027473486000000002,0.138486931,0.154985174,-0.021730812000000002,0.050453477999999996,0.066201538,0.020038848999999997,0.072504025,0.00190336,0.035176847000000004,0.019770124,0.20378294,0.07319092099999999,0.28630921800000003,0.023661129,1.193443681,3.2232906000000003,-2.66321443,-2.384031586,-3.4178030930000003,-3.306620918,-2.100569275,-2.107047279,-3.30078447,-1.676094159,-7.512444019317627,-6.790655136108398,-8.427321434020996,-8.06581974029541,-6.56104850769043 -3156,3156,K190D,0.029619665,0.018094706000000002,0.002788744,0.084752212,0.100962865,-0.030071496,0.09007196699999999,-0.030832637000000003,0.084320886,0.022055194,0.014134218,-0.003960665,0.009538152,0.073222895,0.096281528,0.15889493300000002,0.043030797,1.075612453,3.070360491,-4.047834096,-3.358297592,-4.196962395,-4.632644722,-4.360793472,-3.690472298,-4.55623057,-2.611198743,-7.599304676055908,-8.053638458251953,-9.135687828063965,-9.56215763092041,-7.6633453369140625 -3157,3157,K190G,0.083653955,0.0036218179999999997,0.012560166999999999,0.115267979,0.077161286,-0.061159062,0.080157845,0.087150064,0.11928410099999999,0.0039265409999999995,0.003317094,0.008079678,0.017040656,0.14099088,0.08954507800000001,0.15708878699999998,-0.0027662159999999997,1.234188512,3.071937563,-3.954357947,-3.668315971,-3.3878134380000002,-5.207447662,-4.053275703,-3.4549369580000002,-4.17547608,-1.854062425,-6.965329647064209,-7.132238388061523,-8.639039993286133,-8.279953002929688,-6.799807548522949 -3158,3158,K190F,0.026829027000000002,-0.12065612,-0.051680839000000006,0.022996747999999997,-0.217008299,-0.082375449,0.06905210099999999,-0.015394047,0.303822896,-0.156337366,-0.084974873,-0.015602527,-0.08775915,0.078721355,-0.032727859,-0.040411595,-0.39360500200000004,1.270488892,2.533330658,-7.097180214,-7.2713716129999995,-6.931698272999999,-8.425394798,-7.124956749,-5.732479637000001,-6.209571041,-4.184823022,-10.646430015563965,-9.443951606750488,-10.422403335571289,-10.116884231567383,-10.142743110656738 -3159,3159,K190I,0.08282801299999999,0.02723384,-0.018771113,0.122197355,0.108124379,-0.10018500699999999,0.094393409,0.071262617,-0.062147907,0.060944062,-0.006476381999999999,0.0037918270000000002,-0.041334052999999996,0.207848848,0.036545862,0.200889968,0.01535879,0.967372558,3.056630347,-5.944695491,-5.871439789,-6.525079903,-6.842501671,-5.4228471979999995,-5.061608894,-5.772740852999999,-2.567488527,-9.819920539855957,-7.473382472991943,-8.72268009185791,-8.738823890686035,-8.076661109924316 -3160,3160,K190H,0.049684448,0.017389238,0.0038171840000000004,0.073260169,0.113907221,-0.034282122000000005,0.08664414699999999,0.012724748999999999,0.12690832900000001,-0.024579186,0.059357661,-0.020588703,0.028223071000000002,0.109778631,0.036741707,0.12409977900000001,0.103714662,1.134830888,2.999257431,-2.976281262,-3.352399399,-3.63552626,-3.5012896039999997,-2.9671871189999997,-1.425003929,-4.103015946,-2.385403038,-7.033283710479736,-6.139279365539551,-7.569004535675049,-6.307369232177734,-6.219034194946289 -3161,3161,K190M,0.08332503,-0.006246636999999999,-0.035846314,0.044839563,0.06426857,-0.050357398,0.101536085,0.065113974,-0.075112884,-0.044110595,0.031617321000000004,-0.101677481,0.029984853,0.051754217000000005,0.037924908,0.079340564,0.049196575,1.0578344370000001,2.853788227,-5.124878133,-5.2751310810000005,-5.129668716,-6.2079474789999995,-4.888170845,-4.123472542,-4.722812889,-1.617101485,-8.781522750854492,-6.34840726852417,-8.102238655090332,-8.169919967651367,-7.589532852172852 -3162,3162,K190L,0.062068255999999995,0.036144497000000005,0.0337272,0.110483771,0.09924628,-0.121457433,0.082031517,0.04210499400000001,0.108941825,0.024758912999999997,0.04753008,0.039286632,0.028167768,0.162424627,0.058542914,0.16838051699999998,0.030112042000000002,1.08321687,3.161940692,-4.357624245,-4.189187859,-4.041275627,-5.749778305,-4.630841866,-3.1770375669999997,-4.785073097,-0.8048507420000001,-7.933252811431885,-5.781639575958252,-6.2576398849487305,-7.647208213806152,-7.272622585296631 -3163,3163,K190N,0.077588054,-0.007869114,-0.021035625,0.17126141399999997,0.11623518699999999,-0.078748344,0.09588434800000001,0.059291759000000006,0.034762106,0.020319748999999998,-0.036057976,-0.023380445,-0.018690804,0.17507975899999997,0.167443068,0.140003345,0.092467028,1.098635386,3.12187274,-1.255120435,-1.722629776,-1.229730743,-1.2073258059999998,-0.798408813,-1.3175070340000001,-2.432203271,-2.219738678,-6.236701011657715,-6.300751209259033,-7.052486419677734,-6.7674055099487305,-5.967838287353516 -3164,3164,K190Q,-0.033031008,0.023736287999999998,0.02468798,0.16130820699999998,0.17701405,-0.050846062000000004,-0.05854237,-0.007519645,0.092224103,0.085106939,-0.037634364,0.12610642,-0.07673046,0.26923816100000003,0.053378252,0.288040144,0.065987956,1.33142065,3.565361933,-1.656487144,-1.828385056,-2.2336580809999997,-1.897497978,-1.060336876,-1.262557732,-1.82075844,-1.449972561,-5.661880016326904,-3.499943256378174,-6.082450866699219,-5.866156578063965,-5.568953990936279 -3165,3165,K190P,0.04875832099999999,0.027105125,-0.030132237000000003,-1.54116656,-2.16444907,-0.09460010199999999,0.07719275,0.020323891,0.138727575,-0.0061799540000000005,0.060390204,-0.057393027,-0.0028714459999999997,-1.457132799,-1.62520032,-2.112064997,-2.216833143,0.829209801,0.717584806,-9.035988582,-8.657854446,-9.435519875,-9.506569382,-9.162935905,-8.417063301,-8.816291035,-8.695880952000001,-10.071985244750977,-7.804438591003418,-10.929665565490723,-11.367794036865234,-10.46705150604248 -3166,3166,K190S,0.052101355999999995,0.012444461,0.017023187,0.08815933199999999,0.101368661,-0.09184786199999999,0.05254718,0.051655532000000004,0.159105511,-0.005563883,0.030452805,-0.008870550999999999,0.042916924,0.09430656800000001,0.082012095,0.146532306,0.056205016,1.055509506,2.96653421,-3.1934224330000003,-2.949397385,-3.739954025,-3.81310479,-3.00731398,-2.457341988,-3.602818258,-1.930497076,-6.201094627380371,-5.44442081451416,-7.615726947784424,-6.992443084716797,-6.310786724090576 -3167,3167,K190R,0.059388287000000005,0.034166915,0.027263827999999997,0.121003326,0.134726194,-0.026695691,0.085517604,0.033258969,0.112030158,0.026808794,0.041525036,0.046364432000000004,0.008163223,0.142171569,0.099835083,0.209778827,0.05967356099999999,1.024261699,3.1672944610000004,-1.339058783,-1.237130653,-1.498608902,-1.7063660580000002,-1.629141991,-0.62404631,-2.5121490019999997,-0.134337415,-4.9293212890625,-4.274986743927002,-5.047382831573486,-4.464893341064453,-4.753251552581787 -3168,3168,K190T,0.031442154,0.019029975,0.0029206809999999996,0.09249076099999999,0.142137028,-0.121792833,0.025171078,0.03771323,0.162248032,0.017023252,0.021036698,0.00745841,-0.0016170479999999998,0.150109471,0.03487205,0.237646215,0.046627840999999996,1.160203223,3.253758487,-1.9769778669999998,-1.508473595,-2.504234955,-2.388802971,-1.4770856780000001,-2.006292137,-3.063114498,-1.452826613,-6.329925537109375,-4.904684066772461,-6.769043445587158,-6.190282821655273,-5.3437981605529785 -3169,3169,K190W,0.06670215,2.0600000000000003e-05,-0.013984795,0.089247088,-0.205482836,-0.068286923,0.090452611,0.042951687999999995,0.09058856,-0.002043236,0.002084397,-0.050690436,0.022720846,0.107116412,0.07137776400000001,-0.083540765,-0.327424906,1.155297011,2.294729223,-6.899035202,-7.1532381670000005,-6.930895485,-7.452406792000001,-7.105028824,-5.853606742999999,-6.824246284,-3.986297685,-11.002952575683594,-11.16312313079834,-11.347053527832031,-11.114374160766602,-11.41430377960205 -3170,3170,K190V,0.110414599,0.027055392,0.029952699,0.11070142300000001,0.094288889,-0.087925831,0.099816793,0.121012405,0.17095161899999997,0.015919797,0.038190986,0.011041583,0.048863815,0.151427513,0.069975333,0.172975308,0.01560247,1.016875373,2.950497949,-5.661271236,-5.219789673,-6.2214621889999995,-6.379913826,-5.394115349,-5.091075142,-5.1719610430000005,-2.85580433,-8.90422248840332,-6.8859028816223145,-8.051945686340332,-7.9820637702941895,-7.322004795074463 -3171,3171,K190Y,0.035999566000000004,0.067232282,0.047060162,0.083534659,0.11072970300000001,-0.026863687999999997,0.051406285,0.020592847,0.261262869,0.090837581,0.043626982,0.131171136,-0.037050812999999995,0.125649867,0.04141945,0.215373681,0.006085725,0.9624281170000001,3.0170886739999996,-5.767462352000001,-5.644081009,-6.642833617999999,-6.668387169,-6.0342227479999995,-3.8477872160000004,-5.165993341,-3.4220268010000003,-9.571831703186035,-9.015846252441406,-9.936407089233398,-9.877435684204102,-9.316784858703613 -3172,3172,L191A,-0.059776188,0.005842155999999999,0.00585183,-0.073817836,-1.740208362,-0.032925196000000004,-0.033920126,-0.08563225,-0.021483526,0.025795575,-0.014111263,0.047756335,-0.036052675,-0.047840545,-0.099795126,-1.70812149,-1.772295234,0.6660483460000001,1.31034536,-5.839957387,-6.999184265,-5.0009273069999995,-4.159628098,-7.287010048,-5.753037216,-5.88403837,-3.532099293,-6.83549690246582,-9.146971702575684,-9.249156951904297,-8.75168228149414,-9.87267017364502 -3173,3173,L191C,0.018012068,0.064766801,0.053803178,0.040816542000000004,-1.540306586,-0.024951217,0.081573971,-0.045549835999999996,0.084121055,0.046687225,0.082846377,0.030213795,0.07739256,0.014999944,0.06663313900000001,-1.199666891,-1.880946281,0.6833676609999999,1.336175506,-8.519051564,-9.012254379,-7.562880447,-8.25594664,-9.109028976,-8.655147377,-7.982534082000001,-6.1619902,-9.945526123046875,-11.932592391967773,-10.97840690612793,-11.545741081237793,-10.841602325439453 -3174,3174,L191E,-0.043555289000000004,-0.01730507,-0.6125044270000001,-1.9028242219999998,-3.091910494,-0.05386553400000001,-0.052802555,-0.034308022,-0.028454746,-0.039201473,0.004591334,-0.469107389,-0.755901465,-1.80467654,-2.000971903,-2.9564617739999997,-3.227359214,1.65663859,0.799096426,-10.67940588,-11.12017895,-9.824424095,-9.851792038,-12.21956138,-10.38107295,-10.35567423,-10.06195992,-12.863677978515625,-14.815488815307617,-12.963879585266113,-14.083935737609863,-13.309507369995117 -3175,3175,L191D,-0.038911075,-0.732807909,-1.933339784,-1.881349089,-2.706935997,-0.0031844720000000003,-0.016557443999999998,-0.061264705,0.10760592599999999,-0.7328934109999999,-0.7327224059999999,-2.144666753,-1.7220128140000002,-1.49458493,-2.268113248,-2.521431427,-2.892440567,3.7390675769999997,1.7683123280000002,-10.82870968,-11.1525738,-10.25715211,-10.19130738,-11.79012745,-10.75238766,-10.35567423,-10.06195978,-13.04749870300293,-15.547332763671875,-13.348508834838867,-15.263992309570312,-14.216503143310547 -3176,3176,L191G,-0.017561478000000002,-0.029738274,-1.184604464,-2.059512668,-2.8190958999999998,-0.058443017,-0.020674798,-0.014448157,0.012760616,-0.02402161,-0.035454937,-1.29368819,-1.075520737,-2.140236863,-1.978788473,-2.667099222,-2.971092577,0.689531227,0.09432728,-10.57089603,-11.39756277,-9.565598671,-9.668758163,-11.86182362,-10.36073695,-10.35567423,-10.06195812,-10.599249839782715,-13.657886505126953,-12.573481559753418,-13.361534118652344,-13.61203670501709 -3177,3177,L191F,-0.043325475999999995,-0.064916196,-0.004016675,-0.018522592,-0.063981014,-0.058554392999999996,-0.09235262,0.005701668000000001,-0.053447004000000006,-0.114845314,-0.014987078000000001,-0.022174274,0.014140925,-0.016566351,-0.020478832,-0.106827017,-0.021135011000000002,1.246280512,2.180128282,-5.103042503,-5.235241013,-4.748483673,-5.931625809,-5.02568882,-4.574173203,-5.222541644,-1.549945493,-7.365739345550537,-9.413532257080078,-6.790951728820801,-8.91342544555664,-7.903020858764648 -3178,3178,L191I,0.062241091,-0.033821056,0.030783902000000002,0.026537917999999997,-0.075122951,0.05837182,0.06214767400000001,0.062334508,-0.044021890999999994,-0.128856029,0.061213917,-0.016329038,0.07789684200000001,-0.021593857999999997,0.074669693,-0.087826664,-0.062419237,1.3710261030000002,2.356899824,-3.2084544569999998,-2.789797478,-2.9461277010000004,-2.6135253069999997,-3.739199188,-3.9536226119999998,-4.308825097,-0.724836335,-6.5441179275512695,-6.505702018737793,-5.944239139556885,-5.338521957397461,-5.836957931518555 -3179,3179,L191H,-0.05895876,-0.05676943,-0.032335669,-1.225496,-2.35386511,-0.042467661,-0.04998487,-0.067932649,0.011748596000000002,-0.065858853,-0.047680006,0.012794526,-0.07746586400000001,-1.006870602,-1.444121397,-2.3034894009999998,-2.4042408180000003,1.998396659,1.339675274,-11.17417525,-11.32139128,-10.139121800000002,-11.01269725,-12.23473479,-11.16293111,-10.15137662,-9.151812278,-12.521204948425293,-13.699188232421875,-10.477555274963379,-13.644111633300781,-12.467819213867188 -3180,3180,L191K,0.034661124,-0.210727357,-1.3249637090000002,-2.368774727,-2.566725383,-0.011719908999999999,0.029421245,0.039901003,-0.061680320999999996,-0.299710498,-0.121744215,-1.40167992,-1.248247498,-2.103780615,-2.633768839,-2.477414598,-2.656036167,2.912919216,1.266880981,-10.47715518,-10.96264593,-9.726199883,-9.895066138999999,-11.21703923,-10.584824699999999,-10.35567423,-10.06195785,-14.364809036254883,-15.94146728515625,-15.586193084716797,-13.87385368347168,-16.048324584960938 -3181,3181,L191M,0.046768924,-0.003572198,0.041040194,0.07359428400000001,0.010860928999999998,0.052049754000000004,0.0054540890000000005,0.08808375800000001,0.04639667,-0.067989733,0.060845337,-0.002641821,0.084722209,0.019781593,0.127406974,-0.0016698720000000002,0.02339173,1.306832352,2.660187788,-4.574158328,-5.0967700119999995,-3.992778328,-4.996237892,-5.238987679,-3.546017731,-5.604151706000001,-2.8964312139999997,-7.05515193939209,-7.297832489013672,-6.9603495597839355,-6.983176231384277,-7.321403503417969 -3182,3182,L191N,-0.016918433,-0.000398916,-0.46031679700000006,-1.793718647,-2.564733321,-0.049028709000000004,-0.028787383,-0.005049482,-0.005281826,-0.047898525,0.047100694000000005,-0.39272507700000003,-0.5279085170000001,-1.5419838030000002,-2.045453491,-2.459685831,-2.66978081,1.748137847,0.9113450999999999,-10.54702189,-10.84608856,-9.396377975,-10.31425221,-11.77760453,-10.40078619,-10.35567423,-10.06196007,-10.68604850769043,-13.94228458404541,-10.770859718322754,-13.020942687988281,-13.456189155578613 -3183,3183,L191Q,-0.040736725,-0.025382305,-0.031031258,-1.20523162,-2.104050617,-0.025114123,-0.044604074,-0.036869375,-0.010878397,-0.046066829000000004,-0.004697781,-0.048641649,-0.013420866000000002,-1.114183375,-1.296279865,-2.8302400389999995,-1.377861194,0.767103489,0.7435716309999999,-8.919233947999999,-9.653577683,-7.878621773,-8.363665382,-9.763488113,-8.936816788,-8.91511272,-6.890620775,-11.875394821166992,-13.114748001098633,-11.083205223083496,-12.288471221923828,-12.279703140258789 -3184,3184,L191P,-0.025812619,-1.076675827,-2.06903566,-2.227364915,-2.918265711,-0.040128255,-0.009972771,-0.041652467,0.07170044,-1.203099562,-0.950252091,-2.147511487,-1.990559832,-2.262615937,-2.192113892,-2.787517595,-3.0490138260000004,0.262499949,-0.7299549209999999,-10.66117895,-11.29977943,-10.10428368,-9.779856575,-11.6346221,-10.48735298,-10.33976853,-9.987470731,-10.094526290893555,-13.388786315917969,-13.056962966918945,-14.451194763183594,-13.10264778137207 -3185,3185,L191S,-0.016333601,-0.01827237,0.010130785,-1.662707776,-2.314900941,-0.067036207,-0.005211839,-0.027455362,0.005748683,-0.048884437999999995,0.012339698999999999,0.031340243,-0.011078673999999998,-1.6758773830000002,-1.6495381690000002,-2.48087513,-2.148926751,0.588944459,0.685853919,-8.272700656,-9.025064835,-7.5166185,-7.289787987,-9.716501274,-7.815530685,-8.297106203,-5.796244727,-9.433597564697266,-11.908834457397461,-10.667964935302734,-11.332015991210938,-11.719239234924316 -3186,3186,L191R,-0.032735981000000004,-1.127532557,-2.153819295,-2.2801936730000003,-2.845487107,-0.033077311,-0.013476613,-0.051995348,0.053713819,-1.26097335,-0.994091763,-2.054599881,-2.253038708,-2.099123257,-2.461264089,-2.773787235,-2.917186978,0.121637977,-0.759073797,-10.62409386,-10.94906579,-9.847023047999999,-10.09692328,-11.19254352,-11.03491365,-10.33780824,-9.942447565,-14.674091339111328,-15.261141777038574,-14.682680130004883,-14.843684196472168,-15.56182861328125 -3187,3187,L191T,0.024844332,0.005427876,0.014034733,-0.042890211,-1.584024862,-0.03320954,0.04248524,0.0072034230000000005,-0.010171906999999999,-0.05720374599999999,0.068059497,-0.016246636999999998,0.044316102,-0.09322763,0.007447208,-1.662351264,-1.505698459,0.8761677609999999,1.323265973,-6.647715549,-6.820422272,-6.73479493,-4.781570465,-8.226654114,-6.675135963,-6.911223132000001,-4.560065386000001,-8.259729385375977,-9.607325553894043,-8.995697975158691,-8.348100662231445,-9.68445110321045 -3188,3188,L191W,-0.017274081,0.015300961,0.03019861,-0.22060888399999998,-1.7520991419999998,0.24234797800000002,-0.010026577,-0.024521585,-0.181851106,-0.066270215,0.096872137,-0.023723085,0.084120305,-0.276193423,-0.16502434400000002,-1.7162966869999998,-1.7879015969999998,1.3859966869999998,1.378507776,-9.900976346,-9.978946297,-9.373570457000001,-9.707945427,-10.2954249,-10.14899465,-9.144344099,-7.448499955,-11.133508682250977,-12.995577812194824,-10.568120002746582,-12.53543472290039,-12.460938453674316 -3189,3189,L191V,-0.038041103,0.019414397,0.01213088,0.042499229000000006,-0.31300932600000003,0.001180688,-0.064818154,-0.011264051,-0.012127708999999999,0.04407792,-0.005249126,0.076282177,-0.052020417,0.08105931799999999,0.00393914,-0.210515925,-0.415502727,1.139131189,1.913296832,-4.36171153,-4.713060577,-4.103531609,-2.94987989,-5.03966436,-5.002421211000001,-5.043673885,-1.640404854,-5.7705206871032715,-7.017886161804199,-7.225683689117432,-6.438492298126221,-6.758236885070801 -3190,3190,L191Y,0.0039196,0.009608831,-0.013623645,-0.011806981999999999,-1.555942535,-0.046269527000000005,-0.010525861999999999,0.018365061000000002,0.027798256,0.005545795,0.013671866000000001,0.010500528,-0.037747817,-0.031055986,0.0074420219999999995,-1.418293146,-1.6935919240000001,0.675699114,1.321324272,-7.892167682,-8.037979385,-7.679999176,-8.026649223,-8.446566978,-7.2696436460000005,-6.896882594,-2.739769986,-10.5484037399292,-12.163552284240723,-8.646136283874512,-11.392928123474121,-9.168243408203125 -3191,3191,L192A,-0.030093041,-0.018597648,0.004566675,-0.032185099,-1.556554077,0.00413323,-0.015503578999999998,-0.044682502,0.003284755,-0.043783456,0.00658816,0.008439791,0.000693559,-0.041853207,-0.02251699,-1.447693105,-1.6654150490000001,0.66379259,1.319291736,-4.72954753,-4.137270439,-3.5724570539999996,-6.561465111,-5.062589958,-4.313955086,-4.777098457,-0.202280221,-4.198841094970703,-4.44500732421875,-4.372504234313965,-4.897751808166504,-4.809928894042969 -3192,3192,L192C,-0.072189961,-0.06074313,-0.017870328,-0.061819434000000006,-1.063779785,-0.009946776,-0.053528125,-0.090851796,0.0031686490000000004,-0.0027215359999999997,-0.118764723,-0.049487579000000004,0.013746923999999999,-0.072777275,-0.050861593,-0.728730691,-1.398828879,1.134913898,1.514565605,-7.789434381,-6.730953293,-6.716847015,-9.172089432,-7.562688057000001,-8.764594108999999,-7.11180867,-3.9591517560000002,-7.574569225311279,-7.901206016540527,-8.938627243041992,-7.843453884124756,-8.460103034973145 -3193,3193,L192E,-0.016312019,-0.005492534,-1.192431906,-2.261885403,-2.8290247560000004,-0.14821705,-0.023575416000000002,-0.009048622,-0.059880141,-0.022731462,0.011746393999999999,-1.292486789,-1.092377023,-1.980997907,-2.542772899,-2.945806655,-2.712242856,2.4618966159999998,1.000907241,-9.666221663,-8.421228149,-9.187280212000001,-9.836956131,-10.048214699999999,-10.83742912,-7.739932646000001,-2.360981195,-5.43133020401001,-8.629312515258789,-6.698703289031982,-10.544939994812012,-9.165172576904297 -3194,3194,L192D,-0.0977562,-0.7465218159999999,-1.9299711819999998,-2.302637077,-2.832883323,0.024337091,-0.073482813,-0.122029587,0.013568469,-0.71316072,-0.779882911,-1.835068031,-2.024874332,-1.9953053719999998,-2.6099687819999997,-2.534145388,-3.131621257,3.166304976,1.2488567959999999,-10.32483852,-8.985172951000001,-10.55701305,-11.21356181,-9.843146423,-11.02529835,-7.0842839710000005,-1.9369325880000001,-5.622714042663574,-9.11242961883545,-7.869124412536621,-10.818650245666504,-11.008729934692383 -3195,3195,L192G,-0.02054542,-0.018021733999999998,-0.269382432,-1.97212395,-2.784570413,-0.048436697,0.00196303,-0.043053869,0.025664535,-0.033830449,-0.002213019,-0.220885761,-0.31787910199999997,-2.0327677630000003,-1.911480136,-2.884536999,-2.6846038269999997,1.160947692,0.672098558,-8.995588751,-8.422604247999999,-7.772801163,-9.96720742,-8.737161385,-10.07816954,-6.544715929,-2.8661006710000003,-6.396468162536621,-8.203348159790039,-8.009844779968262,-9.565675735473633,-8.997468948364258 -3196,3196,L192F,0.018059132,0.013732505,0.081264467,0.052959093,-0.042845814,0.008473507,-0.035597165,0.071715429,-0.081348484,0.02380942,0.0036555890000000003,0.12046073300000001,0.042068201,0.054372465,0.051545720999999996,-0.025444519,-0.06024710900000001,1.1765857709999998,2.5441896880000003,-4.061002045,-3.9903556669999998,-3.315355515,-4.827034035,-3.990668472,-4.181596535,-5.177439804,-1.89699271,-5.307764530181885,-7.4978861808776855,-4.9616594314575195,-7.134143829345703,-7.268105983734131 -3197,3197,L192I,-0.069777974,-0.001081698,0.027459208,-0.077981889,-0.063610451,0.090775706,-0.024977776,-0.11457817199999999,-0.027931268,0.009687722,-0.011851118,0.07105025400000001,-0.016131839,-0.05060818,-0.10535559800000001,-0.042905532999999996,-0.084315368,1.293262937,2.444541636,-3.2540302339999996,-2.763771927,-3.42018129,-3.976919296,-2.7916781160000004,-3.31760054,-4.181987799,-2.110439195,-4.334310531616211,-4.761491298675537,-3.6447296142578125,-4.596324920654297,-4.058979034423828 -3198,3198,L192H,0.002827638,-0.021074957000000002,0.018251937,-1.081000003,-1.7914210069999998,-0.068898464,0.030313309,-0.024658034,0.029338594,-0.037038927,-0.005110986,0.016572451000000002,0.019931422,-1.017581766,-1.14441824,-1.880932874,-1.70190914,2.482627962,1.777334189,-9.941204733,-9.223816299,-9.009222076,-9.995435608,-9.023766274,-12.45378341,-6.2548152870000004,-1.906427831,-6.335516929626465,-7.984076023101807,-7.473150730133057,-10.33578872680664,-10.49277114868164 -3199,3199,L192K,-0.011885218999999999,-0.082585491,-1.293341385,-2.342098539,-2.784299155,-0.01344116,0.052918327,-0.076688764,-0.006815572,-0.054553174,-0.11061780800000001,-1.244646347,-1.342036422,-2.279944951,-2.404252127,-2.642693709,-2.925904601,0.69323654,0.082934906,-10.83902905,-8.775747437,-11.56617721,-10.44357752,-9.262011498,-14.14763158,-7.387362891,-2.888252352,-6.828527450561523,-9.44167709350586,-8.700114250183105,-11.786308288574219,-10.034839630126953 -3200,3200,L192M,0.020424973,-0.035529635,0.050145005,0.012442773,-0.01111662,-0.076911852,0.039294164,0.001555781,0.00020821200000000002,-0.016899802,-0.054159467999999995,0.110139794,-0.009849785,0.015649866000000002,0.00923568,-0.002237326,-0.019995913,1.190825765,2.6261859430000003,-4.326503384,-3.801950821,-3.993620064,-4.8600371860000005,-4.138020561,-4.83888829,-5.642897883,-3.136287209,-4.340908050537109,-6.106088638305664,-4.455056667327881,-5.372438430786133,-5.057653903961182 -3201,3201,L192N,-0.066510789,-0.068928879,-0.53117053,-1.98860017,-2.853349806,-0.08928135,-0.049294769,-0.083726809,0.042282662,-0.102189123,-0.035668635,-0.51817757,-0.54416349,-1.8756954680000002,-2.101504871,-2.715565481,-2.9911341310000004,1.739102434,0.796762298,-10.15522688,-8.819087142999999,-8.484116142000001,-11.26751642,-9.557899368,-12.64751531,-7.595864006,-2.240495693,-6.0884480476379395,-8.152002334594727,-7.7925214767456055,-9.511981010437012,-9.62081241607666 -3202,3202,L192Q,-0.035816492000000005,-0.030334247,-0.008216564,-1.556737045,-1.901721304,-0.07225350700000001,-0.037717294,-0.033915689,-0.030206312000000003,-0.06574239700000001,0.005073904000000001,-0.029419805,0.012986677,-1.306928441,-1.806545649,-2.000670417,-1.80277219,2.310706123,1.519088042,-8.99955246,-8.512910271,-8.233344154,-9.799404082999999,-8.140600395,-10.3115034,-6.495590624,-2.3725815409999997,-5.623254776000977,-7.2457380294799805,-6.287116527557373,-9.73488712310791,-8.855916976928711 -3203,3203,L192P,-0.076151972,-1.194151849,-2.355943961,-2.675004871,-2.830189854,-0.055266875,-0.04983382099999999,-0.102470122,0.073053756,-1.329194622,-1.059109075,-2.320333653,-2.3915542690000002,-2.5774810059999997,-2.772528735,-2.9402297639999997,-2.720149943,-0.177793423,-0.829006213,-11.16924901,-10.16042255,-10.51537383,-12.06715256,-11.27947244,-11.82382368,-9.693537361,-6.3019651770000005,-9.987443923950195,-11.507801055908203,-10.962759017944336,-10.862314224243164,-9.69978141784668 -3204,3204,L192S,-0.052541483,-0.007488388,-0.024562893,-0.8683095009999999,-2.098896634,-0.061763032,-0.020935118,-0.08414784800000001,0.018634248,-0.008444171,-0.006532605,-0.033722657,-0.015403129,-0.645945248,-1.090673754,-1.888023554,-2.309769713,1.880949767,1.466201925,-7.370516104,-6.953204765,-5.970887466000001,-8.942981926,-7.358421989,-7.627084373,-6.249580821,-2.322293918,-5.295360565185547,-5.887955188751221,-6.584404468536377,-7.407663822174072,-7.627961158752441 -3205,3205,L192R,-0.069107056,-0.61776422,-2.09799211,-2.295990668,-3.061556477,-0.024888612,-0.037694169,-0.10051994199999999,0.062532852,-0.631930701,-0.603597739,-2.1664185469999997,-2.029565673,-2.069091586,-2.522889749,-2.7105939439999998,-3.41251901,0.621005751,-0.48666955,-9.847440504,-8.514317322,-8.736329132,-10.07694566,-8.260961822999999,-13.64864859,-7.016678992,-1.9257547069999998,-6.921551704406738,-8.152511596679688,-9.030695915222168,-11.92420768737793,-10.433646202087402 -3206,3206,L192T,-0.042714469000000005,0.029272092000000003,0.051726372,0.0017215289999999999,-0.833308562,0.039246727,-0.020944903,-0.06448403400000001,-0.014532755,0.045462563,0.01308162,0.09725369800000001,0.006199046,0.02872325,-0.025280193,-0.5657714770000001,-1.100845647,0.572736437,1.394288648,-4.708355646,-4.498802757,-3.6362300419999998,-5.809624222,-5.306235611,-4.290885597,-4.083399228999999,-1.048326915,-3.901601791381836,-5.20269775390625,-5.909127235412598,-4.669543266296387,-5.143263339996338 -3207,3207,L192W,-0.015367998999999999,-0.040580889,-0.023038293999999997,-0.037028146,-0.9446483179999999,-0.06831121,-0.026788362000000003,-0.003947635,0.014168918999999999,-0.061084042000000005,-0.020077736000000002,-0.032498512,-0.013578075,-0.067797115,-0.006259176,-0.737824818,-1.1514718179999999,1.096908765,1.496590095,-8.171825443,-8.033199554,-7.596383865,-9.367173676,-8.492406487,-7.369963631,-6.534484337,-0.637565123,-7.717260360717773,-9.248778343200684,-7.45566463470459,-10.612601280212402,-10.742507934570312 -3208,3208,L192V,-0.031325134,0.001978786,0.008643689,-0.048912497,-0.100550592,0.07946466099999999,-0.0158382,-0.046812068,-0.071795844,-0.043648560999999995,0.047606132999999995,-0.007948019,0.025235396,-0.071658636,-0.026166357,-0.14899316,-0.052108024,1.319928794,2.123259174,-2.641447591,-2.5141302640000003,-2.4048544240000003,-3.715702827,-2.972101662,-1.600448776,-3.4963505269999997,-0.256577214,-3.697780132293701,-4.096135139465332,-3.18988037109375,-3.2005391120910645,-2.5507946014404297 -3209,3209,L192Y,-0.039728946,-0.0056144969999999995,0.031101041,-0.08741346800000001,-0.9478789259999999,-0.046987919,-0.030339538,-0.049118354,0.016018683,-0.034816721,0.023587728,0.05613717,0.0060649119999999996,-0.07168661,-0.103140325,-0.61651699,-1.279240861,1.136762899,1.562806313,-7.131275522999999,-5.95050705,-6.110677017,-8.04159523,-6.361701309,-9.191897011,-7.686589269,-0.18923414600000002,-5.70334529876709,-8.21941089630127,-5.461587905883789,-9.392273902893066,-9.356498718261719 -3210,3210,T193A,-0.082039368,-0.02523072,0.017990193,-0.006502541,-0.014179751,-0.0028811609999999997,-0.018739441000000003,-0.145339294,-0.002449966,-0.023528021,-0.026933419,0.057729772,-0.021749386000000002,0.009600964,-0.022606046,-0.014632793,-0.013726708999999998,1.153378849,2.522290216,-2.773426036,-2.385111595,-2.8695091169999998,-2.99589859,-2.8797227860000003,-2.736888092,-4.639915959,-1.060856275,-4.3074140548706055,-5.708690166473389,-3.777522563934326,-4.5523600578308105,-5.904343605041504 -3211,3211,T193C,0.029402227000000003,-0.019284908,0.03207698,0.007130841999999999,-0.007992230999999999,0.015254233999999998,0.012275295,0.046529158,0.007272092,-0.019070741000000002,-0.019499075,0.05770244,0.006451519,0.037942613,-0.02368093,-0.026652302000000003,0.01066784,1.325933007,2.691545222,-5.063013963,-3.949146378,-4.784970345,-5.136539536,-5.806743256,-5.637670302999999,-6.148862697999999,-3.250565728,-4.940464973449707,-7.189327716827393,-6.088979244232178,-7.1947340965271,-6.779336929321289 -3212,3212,T193E,-0.023697577999999997,-0.055027854,-0.045130407000000004,-0.029274082000000003,-0.209827896,-0.043163081,-0.042359872,-0.005035284,0.017125616,-0.09717698,-0.012878728,-0.077667595,-0.012593218,-0.050609824000000005,-0.007938339,-0.18958702300000002,-0.23006876899999998,1.495163424,2.213152233,-4.171435013,-3.467381966,-2.554351204,-4.81175209,-3.983860245,-6.039829559,-6.205675985,-0.329497743,-6.06315279006958,-6.838245868682861,-4.303950786590576,-6.7322893142700195,-7.68925142288208 -3213,3213,T193D,0.024874887000000002,0.039178288,0.010549181000000001,-0.003289274,-0.07094539,0.021931107000000002,0.033009825,0.016739949,-0.041528328999999996,-0.0025124329999999997,0.080869009,-0.016066732,0.037165093999999996,-0.005794643,-0.000783904,-0.06001254,-0.08187824,1.31205633,2.46737095,-3.901440347,-3.329843719,-2.8426941219999997,-4.179172867,-3.19577494,-5.959716087,-5.1069804780000005,-1.030134113,-5.803206920623779,-6.917409420013428,-5.372048854827881,-7.274710655212402,-8.698148727416992 -3214,3214,T193G,-0.010004476,-0.011059813,0.011663547,0.006739095,-0.038139974,-0.02345974,-0.021558552,0.001549601,0.007643478,-0.018125782,-0.003993844,0.02785773,-0.004530637,0.033839078,-0.020360889,-0.024483611000000002,-0.051796337000000005,1.235117378,2.449877744,-5.124488888999999,-3.270665428,-4.647929672,-4.9260777739999995,-5.86345639,-6.914315178,-6.454675852,-2.34542645,-5.3643798828125,-6.382786750793457,-5.803123950958252,-6.19258451461792,-7.526695251464844 -3215,3215,T193F,0.018152858,0.006275395,0.014265679,0.013289842,-0.019831781,-0.059170982000000004,-0.027460948,0.063766664,-0.021507539,-0.015958228999999997,0.028509019,-0.041749787000000003,0.070281144,-0.003261345,0.029841028,-0.024150746,-0.015512815,1.2999896229999999,2.6560617509999997,-2.302392981,-0.709044991,-3.0647665710000003,-1.794213799,-3.722325615,-2.22161393,-2.7461979469999998,-1.068535993,-1.2240920066833496,-5.0466084480285645,-1.893437147140503,-3.0808205604553223,-3.1631476879119873 -3216,3216,T193I,-0.045105803,-0.057146867000000004,0.004338608,-4.3e-05,0.000771803,0.035180269,-0.061599348,-0.028612257999999998,0.009497771,-0.069804403,-0.04448933,0.040886827,-0.032209611,0.007684384,-0.007770463000000001,-0.021015332,0.022558937999999997,1.1778150809999999,2.492669546,-4.641043091,-3.3319243469999997,-4.720671089,-4.6573733289999995,-6.032173302,-4.463073387,-5.182928878,-2.231033751,-3.2076854705810547,-4.349658012390137,-2.1504242420196533,-3.417701005935669,-4.164674758911133 -3217,3217,T193H,0.025222996,0.012286865,0.068564979,0.05574968,0.024926095,0.13755857400000002,0.018276304,0.032169687999999995,-0.095103875,-0.0076505359999999994,0.032224265,0.077501195,0.059628763,0.078900156,0.032599203,0.004337792,0.045514397000000005,1.208790157,2.8077500160000004,-4.775592317,-4.0236988369999995,-3.9696038060000003,-5.330397858,-4.566403076,-5.987858009,-6.069661391,-1.831544373,-4.181205749511719,-6.825536251068115,-4.756816864013672,-7.111009120941162,-6.2024126052856445 -3218,3218,T193K,-0.006335289,0.09892026699999999,0.089801819,0.066860645,0.098222012,0.36645111,0.009616214,-0.022286792000000003,-0.06848412,0.101877737,0.095962796,0.105249115,0.074354522,0.048063546,0.08565774400000001,0.08067965,0.115764374,0.981517427,2.801542944,-5.683566974,-6.175537642999999,-4.604824837,-7.470636803,-4.529606063999999,-5.637229522999999,-5.92706598,-0.536928298,-5.576295852661133,-6.889777183532715,-4.2299699783325195,-7.802321910858154,-7.145008563995361 -3219,3219,T193M,-0.033217487999999996,-0.014407732,0.00513787,0.006329894,0.031074253,-0.020824796,-0.077436671,0.011001695,-0.044062977999999996,-0.006522567,-0.022292896,0.081380775,-0.071105036,0.020231088,-0.007571301,0.10466757,-0.042519064,1.036897089,2.81709095,-5.021203539,-3.6143913189999997,-5.383386429,-5.535293114,-6.237929855,-4.335016975,-5.399916452,-2.778858837,-3.282480239868164,-4.493823528289795,-2.6509451866149902,-4.6351118087768555,-4.177652835845947 -3220,3220,T193L,-0.022657796,-0.018740701999999998,-0.007353933000000001,-0.006878583000000001,-0.064364734,0.024469712,-0.027412379,-0.017903211999999998,-0.013162262,-0.03006112,-0.007420283000000001,0.003273709,-0.017981574,0.01914718,-0.032904346,-0.065370369,-0.063359099,1.3716330419999998,2.396912066,-2.07346852,-0.44138317899999996,-2.569027695,-2.236837074,-4.187376343,-0.932718307,-3.451524286,0.9717049609999999,-0.7254319190979004,-2.1286392211914062,0.7432208061218262,-2.4107322692871094,-0.9579166769981384 -3221,3221,T193N,-0.08169658,-0.013329423,-0.019257936,-0.004464028,-0.070475732,0.03457842,-0.09425275,-0.069140409,0.021555052999999998,0.025592764,-0.05225161,0.016586093,-0.055101964,0.053419968,-0.062348024,-0.016298115,-0.12465334800000001,1.160328634,2.481424064,-3.9112312999999994,-4.097652222,-2.672217751,-4.1821021730000005,-3.953627472,-4.650556885,-5.014979316,-0.527588009,-4.698766708374023,-4.8838629722595215,-4.1869707107543945,-6.051191806793213,-6.91486120223999 -3222,3222,T193Q,-0.021139368,-0.029135496,0.023303557000000003,0.000580929,-0.027736966000000002,0.034558165,-0.017545183,-0.024733553,-0.046314035,-0.0051394629999999995,-0.053131528,0.048164766,-0.001557653,0.037978298,-0.03681644,0.026575887000000003,-0.08204981900000001,1.671448915,3.643209181,-5.069660439,-4.0801274869999995,-3.277920692,-6.922854645,-5.414491172999999,-5.652908196,-5.717092732999999,-0.409503591,-4.487396240234375,-5.356208324432373,-3.4775171279907227,-6.202655792236328,-5.952460765838623 -3223,3223,T193P,-0.032785098,-0.213288802,-1.554578691,-2.239535951,-2.585087471,-0.024102722000000004,-0.039672021,-0.025898174,-0.01313174,-0.18022422,-0.24635338399999998,-1.639689955,-1.469467426,-2.125558605,-2.3535132969999997,-2.524456566,-2.645718375,1.13366769,0.047235331,-7.54152103,-6.706070007,-6.908504607999999,-7.586830704,-8.14035009,-8.365849739,-7.933194762,-4.263459388,-7.17282247543335,-10.66765022277832,-7.0715765953063965,-8.034832000732422,-8.872711181640625 -3224,3224,T193S,-0.029120728,-0.014000674,0.016574138999999998,0.003528032,-0.042009722,-0.010574072,-0.043985055,-0.014256399999999999,-0.0068051480000000004,-0.023588772999999997,-0.004412575,0.013257611,0.019890666,0.02647941,-0.019423347,-0.048175943,-0.0358435,1.3011755790000001,2.468360252,-2.382935455,-2.210181595,-1.6847976000000002,-2.034777039,-2.902885033,-3.082036011,-4.604777259,-1.052631108,-4.326356887817383,-4.637344837188721,-3.843301773071289,-5.316178798675537,-5.8518967628479 -3225,3225,T193R,-0.036439898,0.039386964,0.077011459,0.041274339,0.040937953,0.256052041,-0.039807487,-0.033072309,-0.135897621,0.034197495,0.044576432,0.08780204900000001,0.066220869,0.065123174,0.017425503000000002,0.029881907000000003,0.051993999000000006,1.125678591,2.743463773,-5.362511148,-4.083679039,-3.675248428,-7.771865524,-4.763572418,-6.5181903310000004,-5.53081505,0.24490160600000002,-4.398104190826416,-6.3818440437316895,-4.292628288269043,-7.396131992340088,-6.693856716156006 -3226,3226,T193W,-0.026055837000000002,-0.04065817,-0.010479853,-0.021555078999999998,-0.030497122,-0.001091514,-0.028382404,-0.023729269,0.001054612,-0.05800012400000001,-0.023316216,0.000707638,-0.021667343999999998,-0.018693103,-0.024417055,-0.029908081,-0.031086162,1.2929429959999998,2.54436965,-6.196283296,-4.455610435,-6.386380569,-6.391801086,-6.408609711,-7.339014679,-7.1820117329999995,-4.485218426,-5.616735935211182,-10.057199478149414,-6.628751277923584,-7.925994396209717,-7.655716419219971 -3227,3227,T193V,-0.04590588599999999,-0.025494443,-0.000233005,-0.0110451,-0.000500627,0.011385969,-0.051169875999999996,-0.040641895,-0.0043209220000000005,-0.046723269000000005,-0.004265616,-0.009972449,0.00950644,0.00870964,-0.030799839,-0.016586339,0.015585086000000001,1.223862287,2.535234418,-3.0344193280000002,-2.040671104,-2.8969100269999997,-2.717678429,-4.5836535419999995,-2.93318354,-4.767009638,-0.723279789,-3.2439627647399902,-4.902838230133057,-2.425553321838379,-2.9301035404205322,-4.048458099365234 -3228,3228,T193Y,0.020231434,-0.059274043,0.0050051359999999994,0.004253916,-0.049908680999999996,0.033477743,0.015343986,0.025118881000000003,-0.077321639,-0.094206865,-0.024341221,0.007409041,0.00260123,-0.0070694569999999995,0.015577288,-0.074172918,-0.025644444,1.1746679279999999,2.206485219,-4.293355396,-2.2545566790000002,-4.5705214000000005,-4.20582045,-4.883592163,-5.552286285,-5.552407122000001,-2.249611685,-2.6595616340637207,-6.822717189788818,-4.345195293426514,-6.248232841491699,-5.671758651733398 -3229,3229,G194A,0.008782263,0.017356052,0.001437804,-0.012425522,-0.033181736,0.031924606,0.0010896319999999999,0.016474893,0.0027201509999999996,0.018591418999999998,0.016120685,0.025930665,-0.023055058,-0.021452562999999997,-0.00339848,-0.046788955,-0.019574516,1.223670094,2.457657378,-4.855669742,-4.202727653999999,-4.273010025,-5.703035385,-4.547327591,-5.552248055,-4.3804917560000005,-3.9668406330000003,-7.902331829071045,-8.63025951385498,-7.3430867195129395,-7.1204023361206055,-7.757305145263672 -3230,3230,G194C,-0.074171029,0.011931723,-0.012310443,-0.034681491,-0.14188896,0.043011468,-0.057019955,-0.091322103,0.022280808,-0.00199276,0.025856205,-0.007328091,-0.017292795,-0.031635864,-0.037727118,-0.134606817,-0.149171102,1.32564484,2.165305591,-7.750245682,-6.64422699,-6.748844246,-8.586031586,-7.260525574,-9.511600013999999,-6.490268288999999,-4.680526254,-10.169120788574219,-10.404731750488281,-10.186967849731445,-9.261749267578125,-10.688671112060547 -3231,3231,G194E,0.014516342,0.027503057,0.000281661,-0.003042425,-0.00654365,-0.025249902999999997,0.013672338999999999,0.015360344,0.013882435,0.013940988,0.041065125,-0.035487314,0.036050635,-0.035043554,0.028958704,-0.03922821,0.02614091,1.4295704969999998,2.571178546,-3.39613277,-2.88639978,-3.0340473180000003,-4.509987373,-2.280352936,-4.269876442,-3.1798755560000003,-2.87586185,-8.743133544921875,-9.475337982177734,-8.55173110961914,-9.002434730529785,-8.436042785644531 -3232,3232,G194D,-0.004154446,0.00844115,-0.017152778,-0.004588643,0.011114738,0.036840527000000005,-0.025085967,0.016777075,0.07682809,0.00493224,0.011950058999999999,-0.018223326,-0.01608223,-0.030369739,0.021192452999999997,-0.002955513,0.025184988999999998,1.22503257,2.5635841040000003,-3.9803161389999997,-2.8177548289999996,-3.53740799,-5.061411415,-3.3159220960000004,-5.169084366,-4.376996685,-2.004404139,-7.334287643432617,-7.401354789733887,-7.81243896484375,-7.806343078613281,-7.351086616516113 -3233,3233,G194F,-0.041750885,0.013272291,0.014122516000000002,-0.020603002,-0.689851161,0.070116993,-0.042452593,-0.041049176,0.029349052999999996,0.002237664,0.024306917999999997,0.004469867,0.023775163999999998,-0.018695451000000002,-0.022510552000000003,-0.558466227,-0.8212360940000001,0.9918457490000001,1.516484973,-10.38313808,-8.193981972000001,-9.264329849,-11.9670813,-11.03188213,-11.45841513,-7.09898903,-4.684497614,-10.4597749710083,-10.621245384216309,-11.794692993164062,-10.55334186553955,-11.893806457519531 -3234,3234,G194I,0.019379544,0.028645282999999997,-0.0033255740000000004,-0.07924677299999999,-1.6789258969999998,0.007397693,0.011286953999999998,0.027472134,0.042378516,0.013476965,0.043813599999999994,-0.036874309,0.030223161000000002,-0.12597006300000002,-0.032523483,-1.6001630009999999,-1.757688793,0.861362858,1.325403081,-9.791129358,-8.898473358,-8.588000015,-10.38325981,-9.269397881,-11.81651572,-8.697470726,-7.718834949,-12.095542907714844,-12.708307266235352,-13.158533096313477,-10.906450271606445,-12.042035102844238 -3235,3235,G194H,-0.035300038,0.030389773,0.027950977999999998,0.005488016,-0.086449922,0.280133591,-0.0029787290000000003,-0.067621346,-0.19904201300000002,0.053026338,0.007753207,0.032131887000000005,0.023770068,0.0027086370000000003,0.008267394,-0.102732166,-0.070167677,1.077306775,2.05380246,-7.5419094179999995,-6.143261702999999,-6.343967796,-8.444393462999999,-7.0160319289999995,-9.761892197,-6.2378627820000005,-3.304987086,-9.035077095031738,-8.275055885314941,-10.312028884887695,-9.4498872756958,-9.550329208374023 -3236,3236,G194K,0.046313707,0.08788367300000001,0.085578121,0.018087963999999998,-0.08905312,0.27229856399999997,0.066494864,0.026132548999999998,-0.054457035,0.101891759,0.073875586,0.09687471,0.074281532,-0.048123713,0.08429964,-0.123657196,-0.054449042999999996,1.519375409,2.391715016,-4.919286517,-4.248100273,-4.181224144,-6.2812802660000004,-4.3137239460000005,-5.572103958,-4.972720914,-2.835766182,-9.561006546020508,-10.537713050842285,-10.98201847076416,-10.153626441955566,-9.401716232299805 -3237,3237,G194M,-0.011401651,-0.002285493,-0.037325911,-0.010949585,-0.109029557,-0.024610685,-0.005294691999999999,-0.01750861,0.02215354,-0.006998699000000001,0.0024277129999999997,-0.005600646999999999,-0.069051174,-0.055622646,0.033723477,-0.10941084400000001,-0.108648269,1.45268838,2.314535329,-10.09625978,-9.033632256,-8.907912735,-11.07793341,-9.514082275,-11.94773823,-8.501595032,-7.709841927,-11.576545715332031,-11.95803451538086,-12.350065231323242,-10.733413696289062,-12.092120170593262 -3238,3238,G194L,-0.00046727,0.023047439,0.017005463000000002,0.009155372,-0.735460234,0.016973981000000003,0.01114606,-0.0120806,0.046643308,0.038563269,0.007531609,0.041870827,-0.007859900999999999,-0.0062911,0.024601843999999998,-0.491825368,-0.979095099,0.40102240299999997,1.37432973,-8.890255872000001,-7.802645409,-7.983619331,-9.829518494,-8.159678397999999,-10.67581773,-7.014479061,-5.5642483160000005,-10.5440673828125,-10.476068496704102,-11.84887981414795,-9.517868995666504,-11.340287208557129 -3239,3239,G194N,-0.000720232,0.033825713,-0.004738975,0.015689355,-0.09927140699999999,0.070350346,0.025423651000000002,-0.026864113999999998,0.055741825,0.034879804,0.032771621,0.034015901,-0.04349385099999999,0.011301694,0.020077015,-0.094221186,-0.10432162800000001,1.514168428,2.4565161769999997,-5.34141469,-4.150462212,-4.380742111,-6.999095779,-4.567073227,-6.609700118999999,-5.11638179,-2.76677789,-7.346985816955566,-8.005428314208984,-8.9935941696167,-7.71706485748291,-7.241216659545898 -3240,3240,G194Q,-0.04434509,0.008402235,-0.009199908,-0.013222728000000001,-0.031244143999999998,0.034588445,-0.07046425099999999,-0.018225928,0.000797913,0.039416122000000005,-0.022611652000000003,0.016759347,-0.035159162,-0.022176141,-0.004269314000000001,-0.039640001,-0.022848286000000002,1.3900470409999999,2.5568970230000003,-5.439480342,-4.8042290119999995,-4.693183952,-6.353939789,-4.449954689,-6.896094269,-5.221197789,-3.6808132039999997,-9.237054824829102,-9.772830963134766,-10.275639533996582,-9.195981979370117,-9.331363677978516 -3241,3241,G194P,-0.007224916,0.005813494000000001,0.001807947,-0.013510316999999999,-0.198504302,-0.006181981,-0.018387812,0.00393798,0.022548848,0.00800095,0.003626037,0.014756261000000001,-0.011140367,-0.010639677,-0.016380956000000002,-0.16454734099999999,-0.232461263,1.3030431690000002,2.096507555,-7.099125357,-5.930844521,-5.064448067,-7.986045555,-7.661919333999999,-8.852369308,-6.304047142000001,-3.246495168,-7.117338180541992,-9.001194953918457,-7.618044853210449,-8.544218063354492,-9.71021556854248 -3242,3242,G194S,0.011767131,0.031855577,0.007260607,-0.00582411,-0.004549414,-0.0041583,0.012399873,0.011134389,0.025487838,0.028807457,0.034903696,0.028269878,-0.013748663999999999,-0.010312018000000001,-0.001336202,-5.7999999999999994e-05,-0.009040828,1.3001260479999999,2.6362872040000003,-3.972095921,-2.8547378230000002,-3.281643616,-4.961868523,-3.350341995,-5.41188765,-2.6772010440000003,-3.339469533,-7.334875106811523,-8.084633827209473,-7.1778998374938965,-5.809019565582275,-7.3110857009887695 -3243,3243,G194R,-0.0773031,0.082218584,0.067644808,0.015580974,-0.30361416,0.400175459,-0.021685912,-0.132920287,-0.16558842699999998,0.096712282,0.067724885,0.08393966900000001,0.051349945999999994,0.004491825,0.026670122,-0.234183127,-0.373045193,1.279592586,2.0161324730000003,-6.05877892,-4.992234131,-4.79722142,-7.083854492,-5.735860069,-7.684724487,-5.690167497999999,-3.093343664,-8.588666915893555,-9.534467697143555,-10.551874160766602,-9.316239356994629,-8.850916862487793 -3244,3244,G194T,-0.023260199,-0.0064554109999999994,-0.014290415,-0.014268669,0.015216881000000002,-0.022587613,-0.042398318,-0.004122079,0.033666173,0.012739801,-0.025650622,-0.005106729,-0.023474101,-0.009905254,-0.018632084,0.005605748000000001,0.024828013,1.117138758,2.534675568,-4.533199487,-3.59620768,-3.9893631739999997,-5.329018539,-3.534232414,-6.217175629,-4.12106268,-4.181370737,-9.232172966003418,-8.84064769744873,-9.032964706420898,-8.036087036132812,-9.099143028259277 -3245,3245,G194W,-0.009014715,0.005530593,0.025723607000000002,-0.019923878,-1.17832734,0.073097183,0.009595603000000001,-0.027625032999999997,0.014104877,0.026574602000000003,-0.015513416,0.045897108,0.005550106,-0.033537506,-0.00631025,-0.9302599359999999,-1.426394744,0.704758656,1.3616793530000002,-11.46661965,-9.903906768999999,-9.717849205,-12.64815269,-11.88463908,-13.17855051,-9.423639202,-9.985203535,-11.707913398742676,-13.504769325256348,-13.257165908813477,-13.484846115112305,-12.95761489868164 -3246,3246,G194V,-0.018017463,-0.010651925,0.00215504,-0.043235019000000006,-1.411238447,0.051010722,-0.00814613,-0.027888796,-0.0029772740000000002,-0.015966756000000002,-0.0053370940000000006,-0.026750619,0.031060699,-0.086958652,0.000488615,-1.3747719440000001,-1.447704949,1.0510493090000002,1.367314041,-8.869816852000001,-8.299149002,-7.826587402,-9.489960915,-8.154504349,-10.57888259,-8.042026568999999,-6.940368032,-10.745672225952148,-11.187692642211914,-11.153271675109863,-9.414844512939453,-10.542296409606934 -3247,3247,G194Y,-0.008314896,0.025333123,0.032637452000000004,0.016243457,-0.707677085,0.005577294,-0.038945744,0.022315953,0.016295174,0.038082751,0.012583493999999999,0.069178164,-0.00390326,0.02045074,0.012036173,-0.377634266,-1.037719903,0.68022161,1.4905069219999998,-11.03783929,-9.262908928,-10.29203453,-11.89285094,-11.34127741,-12.40012464,-7.383035812999999,-5.86816079,-10.489506721496582,-10.614139556884766,-11.531152725219727,-11.084782600402832,-11.842977523803711 -3248,3248,E195A,-0.04038856,0.033053773,0.054837576,0.048389688,-0.10781960800000001,0.214954758,-0.030259147000000004,-0.050517972,-0.13355383699999998,0.033375983,0.032731562,0.062891376,0.046783776,0.049993592,0.046785784000000004,-0.09308146199999999,-0.122557754,1.167460555,2.19751461,-2.434342494,-2.068805191,-2.57202771,-1.4018918759999999,-3.0401554180000003,-3.088832275,-4.2066898980000005,-1.677416777,-7.239814758300781,-6.8708295822143555,-7.270142078399658,-5.894724369049072,-7.132519721984863 -3249,3249,E195C,-0.163197019,0.012843383,0.012837211999999999,0.004601143,-0.25358973100000004,0.450957528,-0.141687053,-0.184706985,-0.24113799100000002,0.09824425199999999,-0.07255748599999999,0.062943653,-0.037269229,0.031891573,-0.022689287000000002,-0.21537487100000002,-0.291804591,1.12933429,1.896195736,-5.346389555,-4.869292145,-6.046939125,-4.527680519,-5.7471240770000005,-5.540911911,-6.617596878,-4.502375504,-10.773314476013184,-12.213763236999512,-12.518234252929688,-10.318098068237305,-11.447677612304688 -3250,3250,E195D,-0.038450162999999996,0.043654578,-0.034573946,0.042486805999999995,0.014874203,0.048300569,-0.042333592,-0.034566732999999995,-0.008037309,0.016242106,0.07106704900000001,0.015519003,-0.084666895,0.07425376,0.010719851,0.017147607,0.012600799,1.27185811,2.7498258360000003,0.487344681,1.5155127259999999,0.340776825,1.046860062,0.057464607,-0.523890816,-2.013093556,0.374354773,-3.8180150985717773,-3.2872695922851562,-2.361970901489258,-2.737816333770752,-0.905463695526123 -3251,3251,E195G,-0.012313756,0.015974408,-0.002192625,0.029745906000000003,-0.014822188,-0.007474051999999999,0.003180947,-0.027808457999999998,-0.028329887999999998,0.009281787,0.022667028,0.011502431,-0.01588768,0.037391389,0.022100422,-0.010988253,-0.018656122,1.0610303220000001,2.4652918390000003,-1.346216862,-0.608883347,-1.8224222030000001,-0.260312088,-0.831826172,-3.207640503,-2.8495938869999997,-1.59431066,-7.402072906494141,-6.344743728637695,-6.958418846130371,-5.699829578399658,-6.405146598815918 -3252,3252,E195F,-0.433225795,-0.466364546,-0.483548364,-0.799417851,-1.257844668,0.645962689,-0.541345186,-0.32510640399999996,-0.132234863,-0.557189722,-0.37553937,-0.393655935,-0.573440792,-0.952462612,-0.646373089,-1.0642742,-1.451415135,3.60254646,3.082991877,-7.06187328,-6.766275215,-7.785464531000001,-5.79806916,-7.46172477,-7.497832726,-7.954126447,-6.380862934,-11.45020866394043,-12.484521865844727,-11.37308120727539,-11.061580657958984,-11.575108528137207 -3253,3253,E195I,0.435539185,0.073226077,-0.33915059399999997,-0.203475087,-0.923341277,0.296172559,0.5078728370000001,0.36320553200000005,-0.071040402,-0.080068467,0.226520621,-0.393655935,-0.284645253,-0.35040262,-0.05654755400000001,-0.763244204,-1.08343835,2.57133054,2.492226977,-6.495813696,-5.696652977,-6.842241341,-5.642756126,-6.711057831000001,-7.586360207,-7.298311657,-5.667384348,-10.532116889953613,-11.454463958740234,-10.540850639343262,-10.227683067321777,-10.690464973449707 -3254,3254,E195H,0.020034141000000002,0.059504329,0.048392099,0.054972658,0.041473636,0.054948933,0.036076572,0.003991709,-0.079482198,0.049466021,0.069542637,0.054820139000000004,0.041964059000000005,0.070921207,0.039024107999999995,0.036682636,0.046264635,1.090498317,2.811500526,-2.76107944,-1.707558334,-3.6987059560000004,-1.841142448,-2.906142487,-3.651847977,-4.3541613869999996,-2.540602906,-7.257265567779541,-6.782278060913086,-7.8249640464782715,-6.595763683319092,-7.012820243835449 -3255,3255,E195K,0.022640048,0.04188953,0.040246296,0.016746623999999998,-0.015181175,0.247029473,0.043274702000000005,0.002005393,-0.134580943,-0.028236828999999998,0.11201588800000001,-0.05598580000000001,0.136478392,-0.019103668,0.052596915,-0.078575811,0.048213461,1.326909262,2.244538031,-0.43022599799999994,-0.525913307,-0.9244497759999999,-0.38361987299999994,0.193181496,-0.510328529,-3.27520133,-0.278912919,-5.24689245223999,-5.548250198364258,-5.414116859436035,-5.476741313934326,-5.955737113952637 -3256,3256,E195M,-0.122862521,0.234879272,0.10065385199999999,0.065335057,-0.8699149409999999,0.851551072,-0.0018728929999999998,-0.243852149,-0.21601186100000003,0.425081511,0.044677033,0.08346532,0.11784238300000001,0.27284667,-0.14217655699999998,-0.33188044,-1.407949441,0.30139603800000003,1.3903839919999998,-5.696366808,-4.944514702,-6.064701576,-5.212213196,-5.734535759,-6.525868805,-6.293609577000001,-4.234397667,-10.544099807739258,-11.0186128616333,-10.320816040039062,-9.534975051879883,-10.862529754638672 -3257,3257,E195L,-0.084067545,-0.397965874,-0.37679637899999996,-0.6219119470000001,-1.055149919,0.42846297299999997,-0.012882215,-0.155252875,-0.122192925,-0.407427401,-0.388504347,-0.368832351,-0.384760406,-0.664397593,-0.5794263000000001,-0.972503826,-1.1377960120000001,3.140778147,2.793087363,-5.059773688,-4.6001270519999995,-5.802308189,-4.407946723999999,-5.207191765,-5.281294708,-5.996078766,-3.737203751,-10.407781600952148,-11.020650863647461,-10.115131378173828,-9.76404857635498,-10.73923110961914 -3258,3258,E195N,-0.049127584,-0.080440976,-0.036024399,-0.009626675999999999,-0.07625021900000001,0.14506358800000002,0.023339082999999997,-0.121594251,-0.025565012999999998,-0.132597518,-0.028284434,-0.069868788,-0.00218001,-0.036508714,0.017255363,-0.132597518,-0.019902918999999998,1.414912983,2.238588498,-0.466420021,0.247405975,-0.677656853,-0.045178062000000005,-0.662883064,-1.193788101,-2.518482239,-0.7203244000000001,-5.167892932891846,-4.177294731140137,-4.7267303466796875,-4.428989410400391,-3.6746418476104736 -3259,3259,E195Q,-0.020379293,-0.03850404,0.01013564,0.023373832999999997,-0.013494444,0.039016452,-0.014336218000000001,-0.026422367000000002,0.035690356,-0.0008872210000000001,-0.076120859,0.034367086,-0.014095806,0.047237772000000004,-0.0004901069999999999,0.025265497999999997,-0.052254385,1.092391433,2.6684853040000003,-1.6071118999999998,-1.449537735,-2.124439713,-1.088717819,-1.423387398,-1.949476837,-3.428548039,-1.171889624,-5.194242477416992,-5.058614253997803,-5.975411891937256,-4.755552291870117,-5.888369560241699 -3260,3260,E195P,-0.010213574,-7.47e-05,-0.007815853000000001,0.028697208999999998,0.007968436,0.004762216,0.011292844,-0.031719991,-0.003145787,0.010232372,-0.010381813,0.031815609,-0.047447315,0.077719195,-0.020324777,0.026309081,-0.010372209,0.881261428,2.670307651,-1.462621983,-0.8465150220000001,-1.7283849409999998,-0.136476791,-2.1934505840000003,-2.408282578,-3.41096827,-2.089886501,-8.014305114746094,-7.823999881744385,-7.65742826461792,-7.849728107452393,-7.480362892150879 -3261,3261,E195S,0.00928002,0.041292016,0.033530855,0.073607039,0.001405108,0.060100043,0.036323552,-0.017763512,-0.012122454,0.032519831,0.050064199999999996,0.035598137,0.031463572,0.09260433,0.054609748,0.01659494,-0.013784724,1.217359958,2.837393005,-0.872362848,-0.42575180100000004,-1.37399144,-0.072151794,-1.317022667,-1.172896538,-2.809707,-1.070286251,-5.872037887573242,-5.309652328491211,-5.827608108520508,-5.009585380554199,-5.124582290649414 -3262,3262,E195R,-0.035118854,0.028829632,0.00760883,0.021661381,0.002125497,0.177633583,0.003986085,-0.074223792,-0.09213701199999999,0.007145797,0.050513467,0.002305508,0.012912152,0.026446781000000003,0.01687598,-0.015383633,0.019634626000000002,1.19055673,2.5545812619999997,-2.288504901,-1.929339661,-3.166964478,-1.44704171,-2.73958165,-2.159597008,-4.088444817,-0.800399063,-6.726259231567383,-7.411635398864746,-7.560970783233643,-6.958774566650391,-7.500857353210449 -3263,3263,E195T,0.008816169,0.070888909,0.048822095,0.046090901,0.004035174,0.056182639000000006,0.019194368,-0.00156203,-0.042245905,0.060747032,0.081030785,0.041795337,0.055848852000000004,0.027492378999999997,0.064689422,-0.024227642999999997,0.03229799,1.307373761,2.601030351,-0.977319864,-0.492728531,-1.288054619,0.101665535,-1.96776075,-1.239720955,-3.838517192,-0.997731875,-6.186883926391602,-5.6888017654418945,-5.988185405731201,-5.251266956329346,-5.921689987182617 -3264,3264,E195W,-0.009267971,-0.159449441,-0.09586918900000001,-0.13672318,-0.974195725,0.727539807,0.009353437,-0.027889378,-0.341020079,-0.059865080999999994,-0.259033801,-0.062662716,-0.129075661,-0.279046712,0.005600351999999999,-0.5291609979999999,-1.4192304519999999,2.193523213,2.351403295,-6.890139909,-5.913692284,-7.944561118999999,-5.8597783429999994,-7.047232384,-7.685435417000001,-7.652963445,-5.72972932,-11.723167419433594,-13.433412551879883,-11.753591537475586,-12.535261154174805,-12.412043571472168 -3265,3265,E195V,-0.09285711699999999,0.011106946999999999,-0.090780039,-0.06345782,-0.7748448640000001,0.7419667259999999,-0.045999110999999995,-0.139715122,-0.44155445600000004,0.012402382,0.009811511,-0.137158339,-0.044401737999999996,-0.17431136100000003,0.047395720999999995,-0.531930154,-1.017759574,1.7600916309999999,2.003292338,-4.859701041,-4.101743065,-4.991648743,-4.234585013999999,-5.169783875,-5.800744507,-5.8264113889999996,-3.7176565160000004,-9.109710693359375,-10.182977676391602,-9.174777030944824,-8.378741264343262,-9.34253978729248 -3266,3266,E195Y,-0.250920199,0.07093089999999999,-0.213553298,0.043641234,-0.562971902,0.779078983,-0.191604818,-0.310235579,-0.39078507799999995,0.18317296800000002,-0.041311167999999995,-0.092625939,-0.334480656,0.16975326699999999,-0.08247080000000001,-0.268394182,-0.8575496220000001,0.742020426,1.579156875,-5.477763542000001,-4.477521446,-6.185024925,-4.5500226139999995,-5.8455446470000005,-6.330704078999999,-6.759550107999999,-4.655115836,-10.222861289978027,-10.300748825073242,-9.778619766235352,-9.395196914672852,-9.754969596862793 -3267,3267,L196A,0.013511546999999999,-0.023375649,-0.023564118,-0.013781833,-0.014103408000000001,0.008321783000000001,-0.013955126000000002,0.040978218999999996,,-0.027801499,-0.018949799,-0.028771326,-0.01835691,-0.015342286,-0.012221379,-0.016018021,-0.012188794,1.275895449,2.556860795,-0.091525543,0.003977318,-1.1778379140000002,2.06191774,-0.9442897109999999,-0.401395149,-1.537310894,0.41470202700000003,-1.968843936920166,-2.0218687057495117,-0.6740908622741699,-4.356549263000488,-3.731647491455078 -3268,3268,L196C,0.069760885,0.008363096,0.021806966,0.050380667999999997,0.029851428,0.022712748999999997,0.07034801,0.069173759,,0.061388317000000005,-0.044662125,0.04156188,0.002052051,0.025706085,0.07505525099999999,0.049022749000000004,0.010680106000000002,1.189518643,2.987475843,-4.862336287,-3.7546576160000003,-4.947948006,-4.66144416,-5.966102768,-4.981528885,-4.864213715,-2.920735483,-6.259605407714844,-5.239620208740234,-6.265286922454834,-8.418526649475098,-7.514284133911133 -3269,3269,L196E,-0.007915552,-0.041762433,-0.023924637000000002,-0.02754187,-0.008205434000000001,0.012594306000000001,-0.028201504,0.0123704,,-0.032565289,-0.050959576,-0.009950605,-0.037898667999999996,-0.067553008,0.012469268,-0.010071478,-0.00633939,1.224566242,2.396587879,-4.901392635,-3.602012383,-5.153275642,-4.0033951189999994,-4.94045092,-6.807829109,-3.555781645,-3.193917153,-6.560755729675293,-6.403120994567871,-4.910276412963867,-7.693575859069824,-6.508153438568115 -3270,3270,L196D,-0.0045067679999999995,0.01938639,-0.020576894,-0.013560445,-0.00834174,0.02113384,-0.035816384,0.026802847999999997,,0.052817105999999996,-0.014044326999999999,0.024710377999999998,-0.065864165,0.025149336,-0.052270225,0.015939211000000002,-0.03262269,1.186092017,2.550758115,-6.091553067,-4.49899131,-6.4946291810000005,-4.752113411,-6.0149539260000005,-8.697077507000001,-4.69568866,-3.872769361,-6.759678840637207,-7.103245735168457,-6.99783992767334,-8.898506164550781,-8.502249717712402 -3271,3271,L196G,0.034063842000000004,0.0052497509999999995,0.022944604,0.009171503000000001,-0.005089222,0.043119985,0.033669005,0.034458678,,-0.005992725,0.016492226000000002,0.023149122999999997,0.022740085,-0.012856845,0.03119985,-0.03617423,0.025995787000000003,1.254713108,2.470105786,-2.851172108,-1.688632736,-4.065036774,-1.0254158709999999,-3.378366348,-4.098408813,-2.367303133,-1.622627917,-4.898972511291504,-4.980343818664551,-5.490175247192383,-7.671197891235352,-6.607240676879883 -3272,3272,L196F,0.07343807599999999,0.014319513,0.015627428999999998,0.034377646,0.026951397000000002,-0.02047721,0.06183005,0.085046102,,0.012486605,0.016152421,0.02442783,0.006827028000000001,0.007126232,0.06162906,-0.014750518999999998,0.068653313,1.334604692,2.6858635730000002,-4.103047223,-4.338410919,-3.5418743360000002,-3.519350853,-4.678425461000001,-4.437174545,-3.499190281,-1.847053595,-6.240399360656738,-2.9509618282318115,-4.851934909820557,-6.918318748474121,-5.55028772354126 -3273,3273,L196I,0.044951287,0.012109375,0.033721096,0.005935301,-0.000868318,0.012479671999999999,0.009325323,0.080577251,,0.016218656,0.008000093,0.048177492,0.019264700000000003,0.002327349,0.009543253,-0.025111414,0.023374779,1.087457987,2.349038116,0.785169978,1.174452606,0.170403625,1.4748841480000001,1.11228228,-0.006172768,-0.7299555320000001,-0.782241086,-2.7693934440612793,-2.5776984691619873,-2.8233604431152344,-5.264324188232422,-4.703508377075195 -3274,3274,L196H,0.05525830599999999,0.040055925,0.035533666,0.019795313999999998,0.032170135,0.002347854,0.042577023,0.067939588,,0.040594371000000004,0.039517477999999995,0.021187393,0.049879939000000005,0.023581425,0.016009203,-0.005186299,0.069526568,1.285115094,2.716921905,-4.1237758730000005,-2.682754578,-4.4222952189999996,-3.744860168,-4.635109596,-5.133859802,-3.49085863,-3.435329776,-7.339438438415527,-5.595599174499512,-6.451266765594482,-8.040485382080078,-6.008731365203857 -3275,3275,L196K,-0.020741213,0.007963435,-0.030197788,-0.019914961000000002,-0.023462475,0.064083112,-0.025243419,-0.016239006,,0.057766752000000005,-0.041839883,-0.020833268000000002,-0.039562307000000005,-0.0052617869999999995,-0.034568135,0.045726058,-0.092651007,1.218124703,2.7516917419999998,-4.212983546,-2.72179039,-4.460869209,-3.268997505,-3.91226857,-6.700992058,-3.5914703739999996,-3.1618279489999996,-6.3041229248046875,-6.236923694610596,-5.60422420501709,-7.520279884338379,-6.658071517944336 -3276,3276,L196M,-0.034296794,-0.01369696,-0.023029123999999998,0.016470899,-0.005650776999999999,0.000164887,-0.028155211,-0.040438376,,0.006586835,-0.033980754,-0.002522618,-0.043535629000000006,0.047986497,-0.015044700000000001,0.008631686999999999,-0.019933241,1.183163949,2.647552304,-2.204690822,-2.405503021,-1.89712075,-2.145755501,-1.284422409,-3.290652428,-3.6239282960000003,-2.7749630080000003,-4.750324249267578,-4.7979960441589355,-4.619842529296875,-4.9530205726623535,-5.698448181152344 -3277,3277,L196N,0.055590453,0.010300303,0.018395599999999998,0.008056246,-0.017572607,-0.034108976,0.024540162999999997,0.086640743,,-0.010163970999999999,0.030764576000000002,0.016378333999999998,0.020412866,-0.010913511,0.027026002,-0.061884539,0.026739326,1.3540001240000001,2.4117253119999997,-4.630576305,-3.57007901,-5.114263214,-3.813794304,-5.078875877,-5.575869118,-3.650693733,-3.081068441,-5.742292404174805,-5.702831745147705,-6.058680534362793,-8.078137397766113,-6.939497947692871 -3278,3278,L196Q,0.039906886,0.011349413999999999,-0.012393072,-0.001108468,0.020486085,0.020256301,0.035623537000000004,0.044190235,,0.023234875,-0.000536047,-0.029850959,0.005064815,-0.043622296,0.041405361,-0.010698082,0.051670252,1.335417477,2.512888706,-4.582441042,-3.5800466839999996,-5.079060745,-3.7719860310000004,-4.018432205,-6.462679542999999,-4.164736193,-3.7118973310000003,-6.354213714599609,-6.017218589782715,-5.5449981689453125,-7.174591064453125,-5.92594575881958 -3279,3279,L196P,0.025067476,0.022386771,0.00192985,0.005183206,-0.019686099999999998,0.02006191,-0.005732874000000001,0.055867825999999995,,0.023619277,0.021154264,-0.001332088,0.005191787,-0.006173528,0.01653994,-0.032193973,-0.007178225999999999,1.225906852,2.40118045,-4.840714388,-3.5139797130000003,-4.653661491,-3.890343033,-5.378092422000001,-6.767495277,-3.843820837,-3.551915553,-5.244029998779297,-6.824723243713379,-5.3048095703125,-8.316826820373535,-8.162494659423828 -3280,3280,L196S,0.046805005,0.014536051999999999,0.015749972,0.001994899,-0.009026136,-0.013431392,0.033379226,0.060230782999999996,,0.025336095,0.003736008,0.003606878,0.027893065,-0.018199872,0.02218967,-0.025258619,0.007206346999999999,1.20193819,2.4345805119999997,-2.462293846,-1.6819702909999998,-3.112411125,-1.0513495940000002,-3.1251881710000005,-3.340550049,-2.58349418,-2.8359459719999998,-3.691235303878784,-3.778308153152466,-3.6255507469177246,-6.762515068054199,-5.676856517791748 -3281,3281,L196R,0.054531513,0.048388695,0.026178996,0.022509319,0.027352755,-0.010856282,0.045535785999999995,0.063527239,,0.061714822999999995,0.035062567,0.034104712999999995,0.018253278,0.012762261,0.032256376,0.011214247,0.043491262,1.153649773,2.7310517560000003,-2.527773511,-1.51847168,-2.493927834,-2.676964989,-2.358871117,-3.590631935,-2.3050055019999998,-2.2766911569999997,-6.424705505371094,-6.3662824630737305,-6.31413459777832,-7.829453468322754,-7.448251724243164 -3282,3282,L196T,0.017822284,0.008293742,-0.010173642,-0.011032688,0.005459075,0.02100357,-0.000368212,0.03601278,,0.029090212,-0.012502728000000001,0.007074099,-0.027421382,0.004799983,-0.026865358,-0.000503486,0.011421636,1.1471525470000001,2.739505421,-0.057463766,0.303298035,-0.6715425190000001,1.16073378,-0.528620354,-0.551187775,-0.7601076440000001,-1.7098582219999998,-2.4935455322265625,-3.06233811378479,-2.692185401916504,-5.225680351257324,-4.839348316192627 -3283,3283,L196W,-0.0015222529999999999,-0.012566266999999999,0.008912145,-0.012437375,-0.004021524,0.024990033,-0.005712509,0.002668003,,-0.016251841,-0.008880691999999999,0.034916159,-0.01709187,0.000545886,-0.025420636,0.014174508999999998,-0.022217557000000002,1.200270332,2.547443944,-4.867541237,-4.3144935460000005,-5.185991585,-3.990898521,-5.601040871,-5.245281662,-4.158895575,-2.726224217,-8.267976760864258,-5.400222301483154,-7.337014675140381,-9.112100601196289,-8.083388328552246 -3284,3284,L196V,0.010276203000000001,-0.005372231999999999,-0.023952922999999997,-0.01545311,0.02295313,0.032045673,0.005247354,0.015305051,,0.007642746,-0.01838721,-0.002391491,-0.045514355,0.00025563,-0.031161849,0.034748499,0.011157761,1.075444182,2.612986375,1.7183941930000002,1.8289771119999998,0.977991356,2.75218502,1.796577965,1.23623951,-0.997966224,-0.190258578,-1.0996580123901367,-1.431046485900879,-0.5910687446594238,-3.9276344776153564,-3.505188465118408 -3285,3285,L196Y,-0.006163126999999999,0.02663334,-0.00985417,-0.002390429,-0.01937016,0.007733659,-0.026577181000000002,0.014250928000000001,,0.035320516,0.017946164,0.0059129,-0.025621239,-0.01010017,0.005319313000000001,-0.047369987,0.008629668,1.239348798,2.5122110980000003,-5.019418513,-3.660534775,-4.97061454,-4.118027916,-5.722555756,-6.6253595810000006,-4.606030167,-2.7733727669999997,-7.430027961730957,-4.794290542602539,-5.9573869705200195,-8.159507751464844,-5.967393398284912 -3286,3286,L197A,-0.02373761,0.030910595,0.00679504,-0.653330671,-1.6978221230000001,0.047662292,0.025849719,-0.07332493799999999,-0.052145342000000004,0.042514002,0.019307188,-0.00999663,0.023586708999999997,-0.534969087,-0.771692255,-1.627592947,-1.768051298,1.91282619,1.569657129,-14.33855925,-14.68527869,-14.3262761,-14.03139686,-14.71773802,-13.93210659,-7.4147697379999995,-2.455389584,-9.596882820129395,-12.170726776123047,-11.063638687133789,-11.485225677490234,-11.693671226501465 -3287,3287,L197C,-0.08468815199999999,-0.0011807089999999998,-0.034669583,-0.931600656,-2.045410784,0.069618496,-0.071780545,-0.097595758,-0.049442393,-0.018621465,0.016260047,-0.031428102,-0.037911064,-0.697853852,-1.16534746,-1.94427319,-2.1465483780000003,1.900936641,1.4501418869999998,-15.19058721,-14.54637556,-15.68886865,-16.55536907,-14.27505969,-14.88726307,-8.437451121,-4.702317055,-9.817140579223633,-13.096172332763672,-12.502486228942871,-8.47916316986084,-13.826414108276367 -3288,3288,L197E,-0.059060912,0.02084969,0.037753186,-1.282698409,-2.296573983,-0.023808541000000003,0.000554904,-0.11867672800000001,0.05573352,-0.013732545,0.055431925,0.062615367,0.012891005,-0.9348734759999999,-1.630523341,-2.3195955109999997,-2.273552455,1.6730541630000002,1.14794094,-16.77133755,-16.53854823,-17.92340133,-17.64644926,-16.39650708,-15.35178188,-8.391789159,-5.435059967999999,-15.035533905029297,-15.822471618652344,-12.83518123626709,-14.776108741760254,-14.801487922668457 -3289,3289,L197D,-0.080197538,0.048740720999999994,-0.032296513,-2.055621736,-2.265152026,-0.049183194000000006,-0.029963811,-0.130431264,-0.012699574,0.082961884,0.014519558,-0.016987437,-0.047605588,-2.44511489,-1.666128581,-2.01029299,-2.520011061,0.332960202,0.431602035,-18.96284668,-18.90223913,-21.19070544,-19.86143558,-17.28258393,-17.57726931,-10.1188955,-7.750218857,-15.380619049072266,-15.978120803833008,-13.460872650146484,-13.5419921875,-15.82391357421875 -3290,3290,L197G,-0.024151718,-0.010227798,-0.016402429,-0.896759172,-2.0468747119999997,-0.023708635,0.00607678,-0.054380215999999995,-0.008365334,0.004578706,-0.025034301000000002,-0.026898363999999998,-0.0059064930000000005,-0.654828895,-1.138689448,-1.865191655,-2.228557768,1.950233434,1.501140493,-16.33516712,-15.96907021,-17.40682607,-17.04076817,-16.12968028,-15.12949089,-7.135209439,-3.209124218,-11.977869033813477,-14.41323471069336,-13.375958442687988,-14.393363952636719,-14.29784107208252 -3291,3291,L197F,-0.010194751,0.105238352,0.03118113,0.024397783,-1.641900013,0.09514278300000001,0.012685096000000002,-0.033074598,-0.025305865,0.15409637199999998,0.056380331,0.047052595,0.015309665,0.051272585999999995,-0.00247702,-1.303337775,-1.9804622509999998,0.690390095,1.33141229,-10.22195601,-10.28533062,-11.30362936,-10.66267838,-7.877249527000001,-10.98089219,-6.683239695,-3.349526525,-9.612491607666016,-9.920296669006348,-7.862539291381836,-10.190522193908691,-9.875633239746094 -3292,3292,L197I,-0.08438760099999999,-0.032492639,-0.082799487,-0.040662013,-0.537680195,0.001915045,-0.05453011,-0.11424509199999999,0.002426232,-0.030141542,-0.034843735,-0.070846197,-0.094752776,-0.046935335999999994,-0.034388689,-0.38871085899999996,-0.6866495309999999,1.5859541659999998,2.0045595130000002,-9.811884001000001,-9.677166199,-12.29070658,-10.048380400000001,-9.908395042,-7.1347717820000005,-6.180701676,-2.217429491,-8.307968139648438,-8.97707462310791,-8.078046798706055,-9.582559585571289,-9.552047729492188 -3293,3293,L197H,-0.081098016,0.007884811,-0.003634123,-0.09389539599999999,-1.6608918519999998,0.067213149,-0.016498376000000002,-0.145697656,-0.08784299300000001,-0.00459304,0.020362662,-0.021475574,0.014207329,-0.13997286,-0.047817930999999994,-1.487030083,-1.834753621,1.146197058,1.369251595,-16.6228701,-15.504476,-18.08422813,-18.50733913,-14.39391035,-16.6243969,-9.102078377,-6.37422245,-14.095898628234863,-13.257326126098633,-12.43169116973877,-14.162745475769043,-14.028273582458496 -3294,3294,L197K,-0.13044991,0.070248184,0.022180473,0.034133069,-1.7100462269999999,0.121101452,0.035201587,-0.296101407,-0.114400745,0.057813629000000005,0.08268273799999999,0.01156402,0.032796925,-0.051630458,0.119896596,-1.455657648,-1.964434805,0.733091222,1.324843576,-16.58521245,-16.64350282,-19.176035199999998,-16.87603623,-14.61302065,-15.61746734,-9.1729386,-6.753484387,-14.74678897857666,-15.095428466796875,-13.842673301696777,-15.608362197875977,-14.820402145385742 -3295,3295,L197M,-0.197201075,0.069362302,-0.050992398,-0.031921177,-0.51859851,0.065988873,-0.131097712,-0.263304437,0.041392685,0.20309481100000001,-0.064370207,0.118476864,-0.22046166,0.056865042000000005,-0.120707396,-0.282603888,-0.7545931309999999,0.575632978,1.496304006,-8.332552968,-9.189344131,-9.990128197,-8.061936134,-6.4834755170000005,-7.937880859,-6.7787166,-4.407740592,-8.463908195495605,-8.513994216918945,-7.99854040145874,-8.553657531738281,-9.424651145935059 -3296,3296,L197N,-0.079909305,-0.008459412,-0.093345703,-0.40581473700000004,-2.089523293,-0.024413894,0.044211771,-0.20403038,0.018275957,-0.054410117,0.037491294,-0.146672608,-0.040018798,-0.386474346,-0.425155128,-1.7809562190000001,-2.398090366,1.634735838,1.4239285869999998,-15.86103478,-16.54899535,-15.53772618,-17.70119572,-14.47622852,-15.04102815,-8.188958884,-5.500778401,-13.486166000366211,-12.982489585876465,-12.269710540771484,-11.516779899597168,-14.639244079589844 -3297,3297,L197Q,-0.12907553300000002,-0.077810518,-0.065311732,-0.301647647,-1.88757772,-0.010478115999999999,-0.060071821,-0.198079244,-0.0068259869999999995,-0.11033690300000001,-0.045284133,-0.11328962,-0.017333843,-0.287902847,-0.315392446,-1.850592147,-1.924563293,1.5633530709999999,1.3984765909999999,-14.63586214,-15.28351138,-15.77565985,-15.11880817,-12.71246116,-14.28887012,-8.924597773,-6.145635274,-12.43553638458252,-12.614872932434082,-11.531293869018555,-13.822856903076172,-12.600598335266113 -3298,3298,L197P,0.016845873,-0.016613922,-0.00724059,-1.3535414890000002,-1.975856504,-0.038515171,0.011606027,0.022085719,-0.005427859,-0.027375642000000002,-0.005852202,-0.054556364,0.040075184,-1.310168591,-1.396914386,-1.9874301069999998,-1.964282901,2.7725594819999997,1.890368415,-15.2799201,-15.42495692,-16.68807301,-14.87172769,-15.03188857,-14.38295432,-8.175279796,-6.012896349,-10.343801498413086,-13.132806777954102,-11.025668144226074,-13.578857421875,-12.978693008422852 -3299,3299,L197S,-0.022285811000000003,-0.001438346,-0.02522251,-0.367586211,-1.7293676269999998,-0.008146814,-0.015491121000000002,-0.029080500000000002,-0.00822033,0.004619092,-0.007495784,-0.020380217,-0.030064802999999998,-0.316054499,-0.41911792299999995,-1.6588406409999998,-1.799894612,1.511261138,1.416924946,-14.59886027,-15.02694459,-14.034661900000001,-15.72784817,-14.12911869,-14.075728,-7.540516267999999,-4.673359822,-10.673307418823242,-13.089980125427246,-11.523009300231934,-12.812644004821777,-13.101425170898438 -3300,3300,L197R,-0.055881973,0.076828662,0.064752299,-0.054788797,-1.8241070480000001,0.39500082299999995,-0.0025380629999999997,-0.10922588300000001,-0.19920822800000001,0.080783347,0.072873976,0.023049747000000002,0.10645485,-0.11480116900000001,0.005223576,-1.60147995,-2.046734146,0.969068422,1.334456217,-14.69292516,-14.86406073,-15.91568047,-15.4926286,-13.37062941,-13.82162656,-7.999536632000001,-5.541707484,-13.908629417419434,-14.480498313903809,-13.356788635253906,-15.284150123596191,-14.704869270324707 -3301,3301,L197T,-0.017429553,-0.005187169,-0.0028337279999999998,-0.48151009999999994,-1.970737178,0.006274136,0.007599422,-0.042458527,-0.020083583999999998,0.01336471,-0.023739048,-0.035374941,0.029707486,-0.322073525,-0.6409466739999999,-1.828194795,-2.113279561,1.438013215,1.371344602,-14.57646696,-14.5348147,-16.65854028,-13.73897684,-14.65837626,-13.29162673,-8.118491673,-4.387373447,-9.369355201721191,-11.71600341796875,-9.838796615600586,-11.054095268249512,-12.105566024780273 -3302,3302,L197W,0.028174208,-0.018779027,0.033650542,-1.734340475,-2.2530959680000002,0.102615383,0.057163930999999994,-0.000815515,-0.0020152910000000002,-0.044493448,0.006935395,-0.0025817179999999998,0.06988280200000001,-1.8214942490000001,-1.6471866999999998,-2.5170061169999998,-1.989185819,0.637419759,0.67546385,-14.60413,-14.72904951,-15.83919521,-15.53082522,-12.56078399,-14.360796100000002,-8.715948681,-5.836764771,-14.665946960449219,-14.698465347290039,-12.864924430847168,-14.945121765136719,-15.093080520629883 -3303,3303,L197V,-0.04725801,-0.058101129,-0.084076317,-0.11158465,-1.583193307,0.054976992999999995,-0.008788948000000001,-0.08572707199999999,-0.010002618000000001,-0.09692955,-0.019272707,-0.143236,-0.024916634,-0.179781813,-0.043387485999999996,-1.4939855380000002,-1.672401075,1.3863721830000002,1.4199477040000001,-10.72377329,-9.668044037,-13.312131099999998,-10.38218953,-11.49853909,-8.757962692000001,-6.562908557999999,-1.8593383999999997,-7.734350204467773,-9.699886322021484,-8.043992042541504,-9.323427200317383,-9.397856712341309 -3304,3304,L197Y,-0.050337507000000004,0.023080418,-0.030729267999999997,-0.24669205,-1.8213058880000002,0.011798278999999998,0.006615313,-0.10729032699999999,-0.026597767999999997,0.023739937000000003,0.022420898999999998,-0.111166809,0.049708273,-0.26616433,-0.227219769,-1.553564894,-2.089046882,1.41708667,1.4100202590000002,-15.81449498,-15.11707778,-18.65466459,-16.45438425,-12.41579762,-16.43055068,-8.736434597,-6.108585188999999,-14.510696411132812,-13.303648948669434,-11.631877899169922,-13.622635841369629,-13.535430908203125 -3305,3305,T198A,-0.02430502,0.009397561,0.01368525,-0.012103678,-0.05716975,0.103005075,0.009123947,-0.057733987,0.051051028,-0.04758078599999999,0.066375908,0.034468539,-0.007098039,-0.019009263999999998,-0.0051980920000000005,-0.057902269000000006,-0.05643723,1.234517724,2.364232475,-2.518744803,-2.4828212130000002,-2.49092778,-2.9352905810000003,-1.860446693,-2.8242377469999997,-4.003327582,-0.12342196400000001,-5.656574249267578,-4.635544776916504,-6.048007011413574,-4.391406059265137,-4.092942714691162 -3306,3306,T198C,0.009769318,0.068221059,0.006597798,-0.008918587,-0.095859568,0.024798522000000003,0.015738787,0.003799849,0.029790063,0.06365219,0.072789927,0.021671665,-0.008476069000000001,0.018530546999999998,-0.03636772,-0.084723769,-0.106995366,1.291317871,2.309880284,-6.8222442029999995,-6.24074086,-6.0740379639999995,-7.7371591870000005,-6.574850327,-7.484432677999999,-7.405995827000001,-4.21485153,-7.264425277709961,-7.34365701675415,-7.883841514587402,-7.4231767654418945,-8.66440200805664 -3307,3307,T198E,0.009339796,0.007257771,0.015293863000000001,-0.004027421,-0.0266382,-0.013795318999999999,-0.011827491,0.030507082,0.06557773900000001,0.00623732,0.008278221,0.01039142,0.020196306,-0.01322481,0.005169968,0.023226232000000003,-0.076502632,1.0636548909999999,2.643429168,-4.195633488,-3.606579422,-4.210905853,-5.269645081,-3.1255945130000002,-4.765442574,-4.685455694,-1.4725140980000002,-7.352267742156982,-6.582681655883789,-6.783370018005371,-5.766945838928223,-5.333725452423096 -3308,3308,T198D,-0.062204837,-0.034206545,-0.036889812,-0.04560963,-0.222104265,0.050914265,-0.040350261,-0.08405941300000001,-0.037051487,-0.06417205299999999,-0.0042410370000000005,-0.010442395,-0.06333722900000001,-0.037730207,-0.053489052999999995,-0.142463694,-0.301744835,1.56681266,2.358869154,-5.909622392,-3.3802083210000005,-7.113690628,-8.27382679,-4.487704788,-6.292681435,-6.102059639,0.051128202000000005,-6.021549224853516,-5.640627384185791,-6.951242446899414,-5.820592403411865,-6.080785751342773 -3309,3309,T198G,-0.012654676,-0.016008398,-0.02678368,-0.036064507,-0.07310684099999999,0.019895788,0.004219222,-0.029528573,0.040418094,-0.028591704,-0.0034250920000000002,-0.017403992,-0.036163368,-0.046874562,-0.025254452,-0.053916619000000006,-0.09229706300000001,1.4106899,2.57426162,-5.18503795,-4.493016418,-4.682470024,-6.675770844,-5.132036972,-4.9418954930000005,-5.559376275,-0.22678826300000002,-4.259896755218506,-4.4098124504089355,-5.713897705078125,-4.963585376739502,-5.467658519744873 -3310,3310,T198F,-0.004546573,-0.005452129,0.0037566509999999997,-0.017958787,-1.5654307619999999,0.000105479,0.035116276,-0.044209421,0.091106044,-0.042845007000000004,0.03194075,-0.017951997,0.025465297999999997,-0.061819418,0.025901844,-1.315426468,-1.815435055,0.852603014,1.345923356,-8.527825567999999,-8.332944695,-8.113537155,-8.88006041,-7.659754257,-9.652831322,-9.154796617999999,-6.728775792,-9.865148544311523,-9.026459693908691,-10.038143157958984,-8.89179801940918,-10.514993667602539 -3311,3311,T198I,-0.063273551,-0.009961161,-0.012107406999999999,-0.085033599,-1.705973767,-0.01314193,-0.067487959,-0.059059143,0.065676026,-0.010512479,-0.009409843000000001,0.005400666,-0.029615479,-0.084806445,-0.085260752,-1.4893543630000001,-1.922593171,0.836590065,1.331621733,-6.336802771,-6.905911307999999,-5.945918967999999,-6.747490044,-5.190016708,-6.894676826,-7.270542271,-3.9568317339999997,-8.435384750366211,-8.59572982788086,-9.14016342163086,-7.602285385131836,-8.68010139465332 -3312,3312,T198H,-0.024420169,-0.020859985,-0.017254343000000002,-0.011948385,-0.10664656,0.033301512000000005,-0.033646042,-0.015194296000000001,-0.004144022,-0.042091979,0.00037201,-0.020350095,-0.014158591000000002,-0.028398549,0.004501779,-0.085115118,-0.12817800099999999,1.345602054,2.2951076969999997,-5.633867694,-6.016578902999999,-4.906433502,-6.670037262,-4.857148438,-5.719140366,-5.7743796629999995,-1.7672841369999999,-6.622126579284668,-7.142877578735352,-6.577801704406738,-5.4587321281433105,-7.116446495056152 -3313,3313,T198K,-0.010990669,-0.028021214,-0.014451903,-0.049482217,-0.066967809,0.037599825,0.014886719,-0.036868056,-0.031905243,-0.026245745,-0.029796682,0.0010158419999999999,-0.029919647,-0.022781055,-0.076183378,-0.041048667000000004,-0.092886951,1.4113049519999998,2.545440026,-1.857744144,-1.7265197140000001,-1.70435305,-2.052472115,-1.2564380720000001,-2.548937767,-3.931617575,-0.774115152,-5.286782741546631,-5.107449054718018,-5.369986057281494,-3.4120917320251465,-4.056006908416748 -3314,3314,T198M,-0.048000773,-0.009600803,-0.024409602000000002,-0.026338835,-0.368987389,0.040685648,-0.053749923,-0.042251622,0.060363380999999994,-0.038612326,0.01941072,0.001029955,-0.049849159000000004,-0.013053687,-0.039623982,-0.28983566899999996,-0.448139109,1.190991382,1.805726867,-5.748700327000001,-6.059445801,-5.557713347999999,-5.866371254,-4.575555023,-6.684416206,-7.447848932,-4.662686543,-8.588863372802734,-8.771641731262207,-8.39387035369873,-7.920422554016113,-7.535737037658691 -3315,3315,T198L,-0.008753832,0.032829695,-0.0024923429999999997,-0.004815249000000001,-0.607306196,0.04793406099999999,0.0020407,-0.019548364,0.029809652000000002,0.033629404,0.032029985,-0.005387744,0.000403059,-0.006306142,-0.0033243559999999997,-0.39199555799999997,-0.8226168340000001,0.951109855,1.582936389,-3.82050249,-4.089446068,-3.650866974,-4.1759890980000005,-3.045033974,-4.141176338,-5.647929781,-2.699047205,-7.527915000915527,-7.935431957244873,-6.866056442260742,-5.848376274108887,-6.498708724975586 -3316,3316,T198N,-0.023748906,0.019390051000000002,-0.036500896,-0.040954832999999996,-0.088840844,0.054281907000000004,0.005911475,-0.053409287,0.068625935,0.033721728,0.005058374,-0.057460539000000005,-0.015541253,-0.009027636,-0.072882029,-0.067981655,-0.109700033,1.138919645,2.312666501,-3.680244722,-2.387767265,-3.6271511760000004,-5.68516526,-2.902251938,-3.79888797,-5.754093885,-0.11420695900000001,-3.714848518371582,-4.453211307525635,-4.874131679534912,-3.9321842193603516,-4.766787528991699 -3317,3317,T198Q,-0.046244981,-0.033257141000000004,-0.0795992,-0.03555395,-0.08707831199999999,0.04037621,-0.049239675,-0.043250287000000005,-0.005271306,-0.029133691,-0.03738059,-0.130922875,-0.028275524,-0.023257751,-0.047850149,-0.090148542,-0.084008082,1.3930351159999999,2.354162419,-2.7895670089999998,-3.296104805,-2.590100754,-3.18728289,-1.909681839,-2.964664757,-4.254681307,-1.499978185,-5.557913303375244,-6.228857040405273,-6.44406270980835,-4.520779609680176,-3.908276081085205 -3318,3318,T198P,-0.047288657000000005,0.000771711,-0.015981098,-0.021019636,-1.642965451,0.073107128,-0.01773734,-0.076839974,0.040775412000000004,-0.024788157,0.026331579,-0.003420505,-0.028541691,-0.035166422999999995,-0.006872849,-1.509094126,-1.776836775,0.71936057,1.324869684,-5.423520448,-3.876521866,-5.228850967,-5.553514915,-4.894772018,-7.563942474,-4.174025278999999,0.377110995,-6.178766250610352,-5.67388916015625,-6.177883625030518,-5.379444122314453,-6.291013717651367 -3319,3319,T198S,0.03354011,0.01913275,0.004015326,-0.009908356,0.034374676,0.030568501,0.042863787,0.024216433,0.027171957000000004,-0.011798397,0.050063897,-0.026843441000000003,0.034874092,-0.03401127,0.014194558000000001,0.013083553000000001,0.055665799,1.329394115,2.732324823,1.264865793,1.147486298,1.638088768,1.224643387,1.282012894,1.0320976179999999,-1.205200402,1.6751538000000001,-1.917406678199768,0.01357889175415039,-1.9660797119140625,-0.28624725341796875,-2.0957117080688477 -3320,3320,T198R,-0.031109734,0.008442273,0.010616511,-0.014291511000000002,-0.130710025,0.121282454,-0.00567576,-0.056543708,-0.004114056,-0.012427156000000002,0.029311702000000002,0.01342378,0.007809241999999999,-0.010707176,-0.017875846,-0.09393392,-0.167486129,1.312071236,2.2730988080000003,-3.601698499,-4.096873184,-2.818957237,-4.457721588,-3.196193146,-3.4387473369999997,-5.277946362,-1.1883912079999999,-5.377750873565674,-6.3053693771362305,-6.708302974700928,-5.444982528686523,-5.268858432769775 -3321,3321,T198W,-0.043606541,-0.002922031,-0.012878631000000001,-1.3037206140000002,-1.9821144419999999,0.101650931,-0.015805788,-0.071407293,-0.009609625,-0.041578718,0.035734657,-0.043405132,0.01764787,-1.243658798,-1.36378243,-1.927556396,-2.0366724880000002,2.8462297430000003,2.000198331,-9.119641844,-8.919905792,-8.540743767,-10.10304659,-8.104820213,-9.929692863,-9.551342146,-7.836974435,-11.49608039855957,-10.864677429199219,-13.046009063720703,-11.02985954284668,-10.915851593017578 -3322,3322,T198V,-0.039122313,-0.028211985,-0.023886819,-0.034497706,-1.215136884,0.068242245,-0.0037568479999999997,-0.074487777,0.04346811,-0.067264877,0.010840908,-0.042636762,-0.005136875999999999,-0.062503481,-0.00649193,-0.863313958,-1.56695981,1.0773720690000002,1.461354052,-5.806068761000001,-5.585182372999999,-5.511414352,-6.19105201,-5.042835426,-6.699859642000001,-6.523033713999999,-2.797522935,-8.04456901550293,-8.28976821899414,-8.66421127319336,-6.855907917022705,-7.952563762664795 -3323,3323,T198Y,-0.021000305,0.014599615,0.004004614,-0.020075151,-1.5363400930000002,0.059665484000000005,-0.017884,-0.02411661,0.047285371,0.026498367999999998,0.0027008609999999997,-0.002039731,0.010048959,-0.042027895999999995,0.001877595,-1.290292175,-1.78238801,0.759389395,1.3361049170000001,-8.684597238,-9.470485275,-8.217684799,-9.017091934,-7.23429744,-9.483426742999999,-8.227637148,-4.653092039,-9.522762298583984,-8.681982040405273,-9.938072204589844,-7.939519882202148,-10.030197143554688 -3324,3324,L199A,-0.027031687999999998,-0.017196592,-0.028033655,-0.014487156999999999,0.015100529,8.87e-05,-0.027035427,-0.027027949,0.04625177900000001,0.0041767440000000005,-0.038569927999999996,-0.020353345,-0.035713965,0.012653535,-0.041627849,0.015309503,0.014891555,1.200850847,2.7073447880000003,1.95162793,1.194707817,1.4852526780000002,2.490416359,1.909647011,2.678115784,-0.687031912,1.97142271,-1.2465763092041016,-2.1350526809692383,-1.3537018299102783,-1.034974455833435,-2.37113618850708 -3325,3325,L199C,-0.078652536,-0.010805173999999999,0.00030676900000000003,-0.030406042,0.012399982,0.048468403,-0.06959473,-0.087710341,0.044969564000000004,0.030666324,-0.052276672,0.027562775,-0.026949237,0.039484789,-0.10029687300000001,0.026342132,-0.0015421679999999998,1.251126816,2.7770330810000003,-3.4166620030000003,-3.433863495,-3.438786865,-3.3388414539999998,-3.536896133,-3.3349220660000003,-6.324529532000001,-3.700717006,-7.606531620025635,-8.42695140838623,-7.984441757202148,-8.184370040893555,-8.305398941040039 -3326,3326,L199E,0.02022208,-0.037953197,-0.032597793,-0.021098059,-0.004804214,0.001247656,-0.004034397,0.044478555999999995,0.007996771,-0.039667552,-0.036238841,-0.04377618,-0.021419405,0.002678643,-0.04487476,0.015414076,-0.025022503999999997,1.3446759,2.8066103439999996,1.5901170409999998,1.302687744,1.299540833,1.5590134430000002,1.318516762,2.470826424,-2.0370369409999998,1.599302077,-1.2815735340118408,-2.2418222427368164,-0.8145442008972168,-1.459757685661316,-2.5619325637817383 -3327,3327,L199D,-0.040595208,-0.039818674,-0.054353713,-0.040196833,-0.058771055,-0.064835412,-0.062775807,-0.018414609,0.058867015,-0.016726928999999998,-0.062910418,-0.090383995,-0.018323431,-0.021542146,-0.058851519000000005,-0.053720238,-0.063821871,1.435469301,2.507989315,1.057590759,0.6758912659999999,0.571486458,1.325356667,1.12924086,1.585978546,-2.6007879590000003,0.8289577440000001,-2.1308441162109375,-3.386837959289551,-2.327707290649414,-1.8229292631149292,-2.663928508758545 -3328,3328,L199G,-0.033864266000000004,-0.008566498,-0.0407965,-0.022544106,-0.004201456,-0.005685898000000001,-0.046428622999999995,-0.021299908,0.019575926,0.00593859,-0.023071586,-0.032608424,-0.048984575,-0.016100922,-0.02898729,-0.011903493000000001,0.0035005809999999996,1.322113845,2.63932888,-0.08958003699999999,-0.36398304,-0.060746178,0.589893684,-0.356437454,-0.256627197,-4.250416125,0.270899409,-3.4153571128845215,-4.577316761016846,-4.295258522033691,-3.5827503204345703,-3.9523496627807617 -3329,3329,L199F,-0.017045945,0.011424523,0.01892704,0.003213487,0.063373193,-0.101687211,-0.07115254,0.03706065,0.06704360599999999,0.05269354,-0.029844495,0.075124161,-0.037270082,0.054314108,-0.047887135,0.121761435,0.004984951,1.036155153,2.988611183,-3.257868896,-3.353865646,-3.214160736,-3.6948995439999996,-2.9868716280000003,-3.039546928,-6.037922517999999,-3.552481743,-6.181084632873535,-5.451860427856445,-6.120729446411133,-6.136989593505859,-6.324644088745117 -3330,3330,L199I,0.006648490999999999,0.062682639,0.00522337,-0.007024595,0.06277263400000001,-0.03384584,-0.011678718999999999,0.0249757,-0.000792968,0.11674356699999999,0.00862171,0.014560597,-0.004113858,0.012466992,-0.026516181,0.091146146,0.034399122000000004,1.09554221,2.794999549,-1.194504732,-1.65236911,-1.279617973,-1.01912767,-1.091874306,-0.929534599,-4.003958445,-1.484925377,-4.260905742645264,-4.526511192321777,-4.367081642150879,-4.612895488739014,-4.4357452392578125 -3331,3331,L199H,-0.048182027,-0.011434148,-0.038469085,-0.00428956,-0.004857554,-0.019914162,-0.070689457,-0.025674596,-0.040655466,0.006449249000000001,-0.029317543999999997,-0.022970801000000002,-0.053967367999999995,0.025123883,-0.033703002999999995,-0.001196203,-0.008518904,1.671448915,3.643209181,-1.522307787,-1.233090714,-1.216145424,-1.621006851,-1.369052811,-2.172243134,-4.080918322,-1.343540111,-4.5274457931518555,-4.931936740875244,-4.265491485595703,-4.419486045837402,-5.054304122924805 -3332,3332,L199K,-0.082210785,-0.009505674,-0.055498447,-0.078800065,0.048501145999999995,0.090858671,-0.09417493099999999,-0.070246638,-0.037324705,0.027943466,-0.046954814000000004,-0.075362003,-0.035634891,0.003913019,-0.161513149,0.036707647,0.060294645,1.068847326,2.622453332,0.45010658299999995,0.48516745,0.662854179,0.447277229,0.7473067170000001,-0.09207266199999999,-2.620869448,1.3826207940000002,-2.64093279838562,-3.8948123455047607,-2.54376220703125,-2.696232318878174,-3.806509017944336 -3333,3333,L199M,-0.033186398,0.030030665,-0.030539012,0.011792131,0.041551904,-0.030350807,-0.032512778,-0.033860018,-0.017546557,0.08883072,-0.028769391000000002,0.002586035,-0.06366405900000001,0.02957501,-0.005990749,0.1191808,-0.036076992999999995,1.13745858,3.037313811,-1.271333499,-1.49349955,-1.249699219,-1.10516378,-1.402469414,-1.105835533,-4.45667329,-0.923037538,-5.104965686798096,-5.249645233154297,-4.831506729125977,-4.932262420654297,-5.215986728668213 -3334,3334,L199N,-0.022179942999999997,-0.089026972,-0.059748345999999994,-0.08612693699999999,-0.10430702300000001,0.009643383,-3.01e-05,-0.044329785999999996,-0.002429429,-0.160185085,-0.017868858,-0.113335029,-0.006161661999999999,-0.10180231199999999,-0.070451561,-0.10956398,-0.09905006599999999,1.519985004,2.40768186,-0.685409805,-0.8028242259999999,-0.517895821,-1.015296661,-0.126506271,-0.964526047,-3.8731687860000004,-0.380882008,-3.6128387451171875,-4.58462381362915,-3.706853151321411,-3.303403377532959,-3.5643324851989746 -3335,3335,L199Q,-0.03683636,0.015745131000000002,-0.020020164,-0.017761958,-0.02665737,-0.015306065,-0.07681909,0.003146371,0.008164023000000001,0.02647021,0.005020051,-0.029426413999999998,-0.010613913999999999,-0.040848432000000004,0.005324516,-0.072144269,0.018829528999999998,1.255459217,2.31068285,0.20735864699999998,0.054607925,0.333608261,0.433601601,0.368667175,-0.153691727,-3.1514519589999996,0.42151381,-2.794407367706299,-3.384812831878662,-2.29583740234375,-2.571902275085449,-3.6314282417297363 -3336,3336,L199P,-0.053286605,-0.025114700000000004,-0.027665229,-0.030893432999999998,-0.013699019,0.0030036520000000003,-0.068002324,-0.038570886,0.004672419000000001,0.011357622,-0.061587021,-0.016523791,-0.038806667,-0.008906617,-0.052880249000000004,0.00829819,-0.035696227000000004,1.277305372,2.668884747,2.6072608859999997,2.125410118,2.26823056,3.014168175,2.800000595,2.82849498,-0.32526398300000003,2.628795874,-0.2593953609466553,-1.6530766487121582,-0.5549118518829346,0.1507425308227539,-1.843324065208435 -3337,3337,L199S,-0.033089777,-0.023175112999999997,-0.034415472999999995,-0.016419681000000002,0.004816356,-0.020471327,-0.038589716,-0.027589837000000002,0.0064249730000000005,-0.017909915,-0.02844031,-0.01681735,-0.052013595,-0.008628976,-0.024210386,0.02447777,-0.014845058999999999,1.202973848,2.612738961,0.72763315,0.434434555,0.680519577,0.7249530940000001,0.9993557209999999,0.7989028020000001,-2.285986325,0.70741059,-2.1322193145751953,-3.2267699241638184,-2.5918915271759033,-2.2177987098693848,-2.7044973373413086 -3338,3338,L199R,-0.048343644000000005,-0.031977845,-0.037559973999999996,-0.028883189,-0.020615908999999998,0.002825302,-0.061342596,-0.035344692000000004,-0.004254031,-0.018456948,-0.045498742,-0.060877111,-0.014242837,-0.022052544,-0.035713833,-0.03388878,-0.007343036999999999,1.313536315,2.5357030959999998,0.222702208,0.45985980200000004,0.05245153,1.133191315,0.219049904,-0.751041512,-3.231284381,0.701463356,-4.283858776092529,-5.039738178253174,-4.352734565734863,-4.316442966461182,-5.005436420440674 -3339,3339,L199T,-0.030411367,-0.018536086,-0.045893348,-0.007034096,0.004982805999999999,-0.007393435,-0.025793228999999997,-0.035029505,0.03159419,0.00592441,-0.042996581,-0.039581106,-0.05220559,0.036954581,-0.051022773,0.019113566000000002,-0.009147954,1.151316067,2.60658435,0.39018359799999996,-0.157049606,0.325246689,0.56849118,0.676636864,0.537592865,-2.025771979,0.346320251,-2.4179790019989014,-3.280881881713867,-2.5445396900177,-2.549530506134033,-2.6407179832458496 -3340,3340,L199W,-0.015509895,0.0028160790000000004,-0.016694373000000002,0.00904024,-0.034159285,-0.005438928000000001,-0.011210651,-0.019809139,0.019608237,0.000505217,0.0051269409999999994,0.0040118770000000005,-0.037400623,-0.025688593,0.043769073,-0.014400561000000001,-0.053918007999999996,1.152331745,2.430418174,-3.1182080869999997,-2.865300835,-2.951775208,-3.251074608,-3.0064635089999996,-3.516426277,-6.185233166000001,-3.027377113,-8.544923782348633,-7.11265754699707,-7.764623641967773,-8.648171424865723,-9.046899795532227 -3341,3341,L199V,-0.045907332,-0.011172241000000001,-0.05700909,-0.02239062,-0.018299501,0.025046952,-0.045953977,-0.045860686,-0.009813985,0.025448538,-0.04779302,-0.083369994,-0.030648186,-0.009151973,-0.035629266,-0.01427887,-0.022320131,1.2473635490000001,2.50703257,0.334227567,-0.22086610399999998,0.020062904,0.506673843,0.35527419299999996,1.009992996,-2.161832686,-0.230118011,-2.7634098529815674,-3.5983879566192627,-3.04305100440979,-3.44852352142334,-3.753589153289795 -3342,3342,L199Y,-0.026289551,-0.054758716,-0.076301005,-0.10372038199999999,-0.046826307000000005,0.011961406,-0.028762876,-0.023816225,-0.07809968099999999,-0.057563183,-0.051954248,-0.097048491,-0.055553517999999996,-0.10891221699999999,-0.098528547,-0.10149302,0.007840406999999999,1.377105667,2.234997027,-1.6982812319999998,-1.8146072009999998,-1.286404877,-2.148637505,-1.1045009540000001,-2.137255623,-4.591965463,-1.4534543869999998,-6.9725728034973145,-6.4229736328125,-6.370491981506348,-6.453882217407227,-7.107770919799805 -3343,3343,A200C,-0.026611937000000002,0.047657519,0.034244771,0.057625989,-0.053922218,0.014591848000000001,-0.056806994000000006,0.003583121,0.055491137,0.09628950800000001,-0.00097447,0.10137096599999999,-0.032881424,0.074326689,0.040925289,0.036042915,-0.14388735,1.1102709990000001,2.803064708,-6.33652859,-6.165485382000001,-6.927766411,-6.331905533,-5.913112807999999,-6.344372817999999,-7.559379047,-6.191135922000001,-9.976856231689453,-10.519889831542969,-10.674864768981934,-10.156900405883789,-10.201171875 -3344,3344,A200E,-0.029374586,0.025307142999999997,-0.039179385,-0.028328869,-0.011045613999999999,0.027760609,-0.032732952,-0.026016219,0.081445845,-0.02096752,0.071581805,-0.015283969,-0.0630748,-0.002189434,-0.054468304,0.000189394,-0.022280621,1.300420265,2.768342995,-2.06435992,-1.507211639,-2.639424301,-2.996210167,-1.231242271,-1.94771122,-3.7363885569999997,-0.262873058,-3.7392027378082275,-4.420170783996582,-4.5269455909729,-3.8810431957244873,-4.990119457244873 -3345,3345,A200D,-0.070584728,-0.014830798000000001,-0.051548853,-0.000508647,-0.046943255,0.024348387000000003,-0.121569668,-0.019599788,0.11826485199999999,-0.030035781,0.000374185,-0.001506212,-0.101591494,0.031689415,-0.032706708,0.003171994,-0.097058503,1.165366601,2.63846726,-2.948624658,-2.068119225,-2.6593740230000003,-4.752940132,-2.239861061,-3.02282885,-3.4923667089999997,-0.980329441,-4.457705974578857,-5.338542938232422,-5.572480201721191,-4.918773174285889,-5.623056888580322 -3346,3346,A200G,-0.007804846,0.006225709,0.008956813000000001,0.019080766000000002,0.01257536,0.024556248,-0.006477254,-0.009132437,0.068433832,-0.015883937,0.028335355,0.021956316,-0.004042691,0.031197249,0.006964282,0.044902977999999996,-0.019752258,1.215398119,2.910565384,-1.978299922,-2.338692245,-2.365577271,-1.4020961459999999,-1.842778946,-1.942355003,-3.992203035,-1.663032976,-5.195987701416016,-5.928389072418213,-5.868866920471191,-5.777347087860107,-5.8495378494262695 -3347,3347,A200F,-0.018269591,0.063130521,0.036109897,0.033945436,-0.236304149,0.071027026,-0.009470827,-0.027068354,0.001520594,0.060043083,0.066217958,0.036175366,0.036044427999999996,0.033693286,0.034197586,-0.208006904,-0.264601393,1.33632919,2.053517302,-5.242302884,-4.960608925,-6.154960365,-5.737094582,-4.068340485,-5.290510063,-6.155416663,-4.428297016,-8.581777572631836,-9.350544929504395,-8.830784797668457,-9.181583404541016,-9.51518440246582 -3348,3348,A200I,-0.029431769,-0.010061659,-0.04120711,-0.014574678,-0.106340364,0.052785942999999995,-0.052675550999999994,-0.0061879859999999995,0.10357502199999999,0.008250075,-0.028373392,-0.014977156,-0.06743706299999999,0.007808784,-0.03695814,-0.089685625,-0.12299510300000001,1.538507605,2.53660855,-5.603560627999999,-5.41130365,-6.753201004,-5.8156597979999995,-4.64561525,-5.392023438,-6.260061696,-4.579612149,-7.163467884063721,-8.515584945678711,-6.610459804534912,-7.903470516204834,-8.273484230041504 -3349,3349,A200H,-0.039130902,-0.0026757459999999997,0.01115046,0.006564284,-0.037725566,0.031114033,-0.010355144,-0.06790666,0.10825227400000001,-0.034216091000000004,0.028864599999999997,-0.048207072999999996,0.070507992,-0.016409016000000002,0.029537584,-0.039301588,-0.036149543,1.308833034,2.463800836,-3.2820957,-3.2462351760000003,-3.498612625,-3.588377975,-2.1990896,-3.878163124,-4.624581411,-2.955316012,-6.316533088684082,-6.6375298500061035,-6.88118839263916,-6.144030570983887,-6.526539325714111 -3350,3350,A200K,-0.046845057,0.057763844,0.04576431,0.08728239900000001,0.018088694,0.046833127999999995,-0.063053213,-0.030636901,0.082408805,0.080072716,0.035454971,0.111316635,-0.019788015,0.190675445,-0.016110648,0.110181067,-0.074003679,1.190057792,2.955570893,-1.4770100830000001,-1.312795235,-2.202541344,-1.82094339,-0.155411606,-1.893358841,-2.830076528,-1.282424531,-4.392410755157471,-5.087371349334717,-4.221807956695557,-4.695695877075195,-4.1515302658081055 -3351,3351,A200M,-0.026123703999999998,-0.08255014,-0.003295781,0.011973399,-0.146867379,-0.018347889,-0.032214754,-0.020032654,0.047360281,-0.09884783300000001,-0.066252447,-0.014977156,0.008385595,-0.014467611000000002,0.038414409,-0.15853816099999998,-0.135196597,1.4590584169999998,2.24694427,-5.356369023,-5.305223801,-6.302295021,-5.559234153999999,-4.548955055,-5.066137085,-6.45680444,-4.702264092,-7.8886590003967285,-9.032904624938965,-7.611883163452148,-8.54827880859375,-8.856548309326172 -3352,3352,A200L,-0.0019330220000000002,0.02798274,0.030829616,0.034769545,-0.12438273300000001,0.214731182,0.02344186,-0.027307902999999998,-0.069044221,0.015051492,0.040913987,0.02127924,0.040379992,0.02578114,0.043757949000000004,-0.11692251,-0.131842955,1.425823516,2.354397789,-4.361027431,-4.179353676,-5.614958961,-4.580447685,-3.1347534560000003,-4.295623375,-5.62626058,-3.46046372,-6.568678855895996,-8.007534980773926,-7.1257643699646,-7.657845973968506,-7.745286464691162 -3353,3353,A200N,-0.011494978999999999,0.052525012,0.041116671,0.078990531,0.02956398,0.021742547999999997,-0.04373457,0.020744613000000002,0.071085774,0.070103069,0.034946955,0.075302278,0.006931064,0.114835931,0.04314513,0.013645377,0.045482583,1.110969013,2.691206778,-2.879820033,-2.288303352,-2.74953141,-4.123475548,-2.473652351,-2.764137505,-4.640253976,-2.380705622,-5.10681676864624,-5.410678863525391,-4.695765018463135,-5.371925354003906,-4.8387837409973145 -3354,3354,A200Q,0.050251820999999995,-0.020079153,0.013416539,0.001007609,-0.005148779,0.031591423,0.068517009,0.031986632,0.061461126,-0.055616365999999993,0.01545806,-0.030280843999999998,0.057113921,-0.008950219,0.010965436,-0.014741093,0.004443535,1.36370701,2.6209023940000002,-1.920512555,-1.749687454,-2.592502975,-1.898997017,-1.17666391,-2.184711418,-4.013512981,-1.596853708,-4.492778301239014,-4.75905179977417,-4.767496585845947,-4.4858503341674805,-3.4213387966156006 -3355,3355,A200P,-0.028145702,-0.015341938000000001,0.001648625,0.003219712,-0.031745666,0.039133998999999996,-0.029668739,-0.026622664,0.062842462,-0.022248584,-0.008435291,0.009600264,-0.006303015,0.006131646,0.000307778,-0.007101108,-0.056390222999999996,1.132273025,2.457200025,-2.215237064,-2.620083817,-2.587442162,-2.71604171,-1.61091188,-1.54170575,-3.194475992,-0.9909762679999999,-3.537600517272949,-4.044067859649658,-4.57855224609375,-3.7032957077026367,-3.232448101043701 -3356,3356,A200S,0.005234763,-0.02556681,-0.005082739,-0.000237133,-0.014845208,0.012398618,0.003561638,0.006907887,0.034065912000000004,-0.04798591,-0.00314771,-0.010515301000000001,0.000349824,-0.013959346999999999,0.013485081999999999,-0.018194692,-0.011495723000000001,1.6804900280000001,3.618873133,-0.49237164899999997,-0.543315247,-0.429975334,-0.618816551,-0.4020019,-0.46774921399999997,-2.68976813,-1.039618749,-4.12256383895874,-3.820702075958252,-3.9057459831237793,-4.6437458992004395,-4.086650371551514 -3357,3357,A200R,0.004946159,-0.003826467,0.022129448,0.03527823,0.021184161,0.025017957,0.0016853410000000001,0.008206976999999999,0.048385631,-0.015124918000000001,0.007471985,0.023881648999999998,0.020377247,0.044994510999999994,0.025561947999999998,0.035558831,0.00680949,1.121916643,2.79062175,-2.107368005,-1.7078536830000002,-2.768899689,-2.106760689,-1.272521233,-2.680804733,-3.268198941,-1.3884089080000002,-5.530444622039795,-6.606733322143555,-5.516280651092529,-6.213948726654053,-5.4967851638793945 -3358,3358,A200T,-0.003696762,-0.007576229,0.017188402,0.020583766,-0.004445483,0.027038771,-0.006686813000000001,-0.0007067110000000001,0.047373247,-0.020707154,0.005554697,0.025972076,0.008404726999999999,0.032392366,0.008775165,0.008876496,-0.017767462,1.229262094,2.64094817,-1.4326009219999998,-1.500982338,-1.825462746,-1.3863909909999999,-1.029659264,-1.42050927,-2.659399263,-1.610479948,-4.629290580749512,-4.580865383148193,-3.8206543922424316,-5.328107833862305,-4.672703742980957 -3359,3359,A200W,-0.044046295,-0.012560905,-0.017588727,0.009104568,-1.124258477,0.057042598,-0.02910655,-0.05898604,0.003531155,-0.029761749,0.00463994,-0.00174889,-0.033428564,0.010881288000000001,0.0073278480000000005,-0.9201957590000001,-1.328321195,0.718093897,1.3671650780000002,-6.036016387999999,-6.064901756,-6.236705299,-6.485004654,-5.147675331,-6.245794899,-6.720253791,-5.111194655,-10.326997756958008,-11.71898078918457,-10.639066696166992,-10.389427185058594,-10.97532844543457 -3360,3360,A200V,-0.007062774,0.050735117999999996,0.020328242,0.025989164,-0.017479696,0.02233301,-0.011824362,-0.002301186,0.021825551000000002,0.08478989099999999,0.016680344,0.053025882999999996,-0.012369399,0.05095116,0.001027168,-0.005128624,-0.029830767999999997,1.543610422,3.106887046,-3.676340923,-3.1961958310000003,-4.759832581,-3.9991542589999995,-2.914144051,-3.512377892,-4.810783426,-2.7948060710000004,-5.810096263885498,-7.004638195037842,-5.248929500579834,-6.381132125854492,-7.119194030761719 -3361,3361,A200Y,-0.021652706,-0.037985166,-0.034170978,-0.024685983999999998,-0.11624887800000001,0.009581237,-0.042611712999999996,-0.000693699,0.11714216,-0.025409547999999997,-0.050560783,-0.02751886,-0.040823095,-0.024286457,-0.025085511,-0.017903685,-0.21459407100000003,1.232115325,2.429077035,-4.867099884,-4.744533501,-5.629223709,-5.517648353999999,-3.2367213130000003,-5.207372543,-5.581615655,-3.710639922,-8.712919235229492,-9.315240859985352,-8.042264938354492,-8.583480834960938,-9.05916976928711 -3362,3362,S201A,0.058912639,0.075785461,0.035453647000000005,0.011202742,-0.031490122,0.034466881,0.062018142000000005,0.055807135,0.054150194000000006,0.058552512,0.09301841,0.045320039000000006,0.025587254,0.008957839,0.013447645,-0.015205865,-0.047774379000000006,1.136862586,2.473260191,-5.015778911,-4.525545143,-5.794193358999999,-6.027866684,-3.889876305,-4.841413063,-3.940772615,-0.96982833,-6.525453567504883,-4.593867301940918,-7.239696979522705,-7.64842414855957,-8.273120880126953 -3363,3363,S201C,0.080602776,0.10764683,0.043359389000000005,0.042955041,-0.840956088,0.143920691,0.128008641,0.03319691,0.047132176,0.027955272000000003,0.187338387,0.084618531,0.002100247,-0.018510915,0.104420996,-0.550014685,-1.131897491,0.8437788940000001,1.4927084830000001,-10.68418734,-10.89577136,-11.67805361,-11.63821697,-9.82550769,-9.383387054,-8.622655714,-5.1785485289999995,-11.35412311553955,-9.135891914367676,-10.169267654418945,-11.841660499572754,-11.536236763000488 -3364,3364,S201E,0.04842020599999999,0.008935469,-1.267088602,-2.261866755,-2.7645417219999997,0.096039068,0.075155531,0.021684881,0.042426881,0.020594172,-0.002723235,-1.292488377,-1.241688827,-2.182680679,-2.341052831,-2.933691983,-2.59539146,0.520758176,0.061040860999999995,-8.518540659,-5.967336609,-8.74648597,-11.33289661,-7.82415863,-8.72182547,-5.1283255819999995,-2.179564379,-9.991580963134766,-6.319327354431152,-10.639063835144043,-11.563511848449707,-11.205000877380371 -3365,3365,S201D,-0.006148843,0.029843457,-0.450277439,-2.168001972,-2.588748537,0.0054701030000000005,0.001304935,-0.01360262,-0.028970281,0.034047223,0.02563969,-0.355875355,-0.544679523,-2.388735161,-1.9472687819999999,-2.139746465,-3.0377506089999997,1.0867144709999998,0.47962756700000003,-7.512343587999999,-5.828881813,-6.848253028999999,-9.755699974,-7.842187416,-7.286695709,-5.30612809,-1.700953039,-9.988574981689453,-7.07234001159668,-9.994911193847656,-11.388051986694336,-11.193704605102539 -3366,3366,S201G,0.035568879,0.057968918,0.015578802,0.002437304,-0.06664576900000001,0.053234026,0.027449603,0.04368815400000001,0.017634112,0.026937261,0.089000575,0.022748163,0.008409441,-0.022269274,0.027143881,-0.063387213,-0.069904324,1.2166231140000001,2.35890501,-7.449653735,-8.414598816,-6.847459137,-8.450563751,-6.298477432,-7.23716954,-5.764700047000001,-2.667625788,-7.175647258758545,-5.395094871520996,-7.721973419189453,-9.105575561523438,-9.167943954467773 -3367,3367,S201F,0.049190227999999996,0.07344990900000001,0.005042318,-0.956098951,-1.8746631130000002,0.09315016,0.059160091,0.039220364,0.002650112,0.038538416,0.108361402,0.000297645,0.009786991,-0.853830805,-1.058367096,-1.860114614,-1.889211612,2.179448238,1.598394009,-11.806322699999999,-13.51024082,-13.92246842,-11.48317596,-11.7319626,-8.383765694,-7.689822272000001,-4.459539285,-13.731063842773438,-11.442621231079102,-12.234471321105957,-14.120278358459473,-12.966219902038574 -3368,3368,S201I,-0.031273503,0.047907902,-0.065810406,-1.671864169,-2.5441557280000002,0.108963508,0.014411825,-0.07695883099999999,0.019731305,-0.0018569320000000002,0.097672735,-0.042167276,-0.089453536,-1.9283196,-1.4154087380000002,-2.156452159,-2.931859297,0.908308158,0.674327355,-12.98294311,-13.72494852,-15.29630914,-14.48760004,-10.34980784,-11.05605002,-7.5943017489999995,-3.9026653639999997,-11.918246269226074,-11.59670639038086,-12.709611892700195,-14.037554740905762,-13.629886627197266 -3369,3369,S201H,0.151057406,0.138598553,0.089693922,0.08745704300000001,-0.334359694,-0.051183623,0.018405424,0.283709387,-0.027610986,0.195774005,0.08142310000000001,0.121573545,0.057814298,0.10711013800000001,0.067803948,-0.228312452,-0.440406936,0.8400508809999999,1.7109388330000002,-9.094187946,-10.76593639,-9.384600571,-10.22636851,-7.560330337999999,-7.533703918,-5.620228354,-2.196514976,-10.628358840942383,-7.473094940185547,-8.87202262878418,-11.812119483947754,-10.463186264038086 -3370,3370,S201K,-0.092811746,-0.009571605,0.03806445,-0.014802606000000001,-1.509409538,0.13352033,-0.022517407000000003,-0.163106085,0.034601543,0.055016747000000005,-0.074159957,0.080747837,-0.004618937,-0.006525528,-0.023079682999999997,-1.25608503,-1.7627340459999998,0.700254982,1.335633859,-10.64617295,-8.505343575,-12.51777921,-13.39937077,-7.897706337000001,-10.91066483,-6.048756889,-2.108589629,-9.631342887878418,-4.54396915435791,-11.64563274383545,-11.84952449798584,-12.225356101989746 -3371,3371,S201M,0.009987963,0.12574861199999998,0.069701232,0.066017724,-0.147038285,0.043895555,0.048647055999999994,-0.02867113,0.029837752999999998,0.139615226,0.111881997,0.12446441,0.014938053,0.092686285,0.039349162,-0.10118307,-0.192893499,1.1185417359999998,2.212869614,-12.07658529,-12.37099459,-12.22245094,-14.02111259,-9.893419159,-11.87494916,-7.519496413,-3.824881271,-12.099690437316895,-7.792684078216553,-12.071243286132812,-11.751683235168457,-12.598976135253906 -3372,3372,S201L,0.045287467000000005,0.10275679900000001,0.054844124,0.02906642,-1.396292631,0.12953978300000002,0.040121781,0.050453153,0.036773397,0.075733858,0.12977974,0.08470503800000001,0.024983209,0.016383837,0.041749003,-1.139869862,-1.6527154,0.65336427,1.3387569940000001,-11.35795939,-12.32415085,-11.89856492,-14.03701805,-9.584003433,-8.946059715,-6.858910255,-2.348337164,-11.071534156799316,-9.638763427734375,-11.78078842163086,-12.519469261169434,-12.654516220092773 -3373,3373,S201N,-0.071533666,-0.005406604000000001,0.021706694,-0.025106682,-0.239890997,0.029382441000000002,-8.87e-05,-0.142978631,0.070576763,-0.08855029699999999,0.07773709,0.029730918,0.013682469,-0.011246778,-0.038966586,-0.131945364,-0.34783663,1.4658252630000002,2.323398534,-6.735959922999999,-6.675410995,-6.131783165,-9.093244171,-5.93486322,-5.844498062,-5.37557227,-2.6193096540000003,-7.849056243896484,-6.054628372192383,-8.546975135803223,-9.817591667175293,-9.500785827636719 -3374,3374,S201Q,0.033885989,0.088679825,0.038422615,0.04016824,-1.569776964,0.079417324,-0.009216911999999999,0.076988889,0.110109888,0.10731961,0.070040039,0.08345733799999999,-0.0066121090000000006,0.113008568,-0.032672089,-1.3993837759999999,-1.7401701509999998,0.435615855,1.312020926,-9.63957339,-8.279954117,-10.93554783,-12.57107229,-7.666596687,-8.74469603,-5.7993409620000005,-1.78087795,-9.200996398925781,-4.915611267089844,-9.098719596862793,-10.356101989746094,-9.800785064697266 -3375,3375,S201P,0.024611212,0.021190739,-0.019472077,-1.613393625,-2.184156114,0.035446489,0.0247691,0.024453324,0.032469592,0.013437682,0.028943795,0.006980343000000001,-0.045924495999999995,-1.5780653969999998,-1.648721852,-2.312989881,-2.055322346,0.646431506,0.6969314940000001,-10.050775699999999,-9.229124176000001,-12.16369623,-9.80280497,-9.063842079,-9.994411026,-7.84256926,-4.747873306000001,-10.249906539916992,-6.428078651428223,-11.648811340332031,-10.750643730163574,-11.22519302368164 -3376,3376,S201R,0.005019381,0.042968997,-0.004749115999999999,-0.01867951,-1.3981916840000002,0.141787874,0.010544136,-0.000505375,-0.00453762,0.004248656,0.081689338,0.005481418,-0.01497965,-0.025375047999999997,-0.011983971999999999,-1.195087573,-1.601295794,0.590299237,1.3305155659999999,-11.56515545,-10.14757697,-12.11717044,-15.22759116,-9.116005898,-11.21743277,-6.59070918,-2.818470642,-10.574411392211914,-7.788131237030029,-11.03260612487793,-11.68871021270752,-11.65966510772705 -3377,3377,S201T,-0.009666123,0.016144153999999997,0.021141023,0.009639763,-0.745591461,0.030912736,0.018662416,-0.037994661,0.002343965,-0.009024187,0.041312494,0.014352998,0.027929047000000002,-0.00453169,0.023811216,-0.524030928,-0.9671519940000001,0.798774203,1.4656054219999999,-5.781961555,-5.82442691,-6.10699894,-7.266625259,-3.982652672,-5.729103996,-5.585314202999999,-2.800630659,-7.554621696472168,-6.809554100036621,-9.175554275512695,-9.829644203186035,-8.167510032653809 -3378,3378,S201W,0.00033607099999999996,0.023022663,-0.07044711099999999,-1.6413638640000001,-2.368502358,0.112515205,0.013499097,-0.012826956,-0.043266869000000006,-0.00496738,0.051012706,-0.030078924,-0.110815297,-1.537154994,-1.745572734,-2.3673475440000002,-2.369657171,0.8298883979999999,0.7113701440000001,-13.02165139,-13.713422099999999,-13.98080469,-15.27960901,-11.01376413,-11.12065701,-8.00235837,-4.83075208,-14.31517505645752,-11.393823623657227,-13.194866180419922,-15.565774917602539,-12.974520683288574 -3379,3379,S201V,0.018122688999999997,0.048866355,0.04137407,-1.0754517829999999,-1.9466466830000002,0.056253988,0.024981233999999998,0.011264143,0.038062075,0.03518336,0.06254935,0.05305145,0.02969669,-0.862389599,-1.288513966,-2.046370194,-1.846923172,2.129355032,1.5136838119999998,-11.15350388,-10.95374879,-13.63205905,-12.67400446,-8.002326874,-10.50538023,-7.173079853,-2.609197494,-10.524946212768555,-10.042384147644043,-11.41630744934082,-12.905374526977539,-13.176185607910156 -3380,3380,S201Y,0.031201891000000002,0.048717215999999994,0.029395108,-0.18720972,-1.529393499,0.066987247,0.020020949,0.042382832999999995,0.025314572,0.015777993,0.081656438,0.06843177,-0.009641554,-0.137779257,-0.236640182,-1.4554585780000002,-1.60332842,1.032613574,1.355593448,-10.9954052,-13.73526484,-12.74059484,-10.57682082,-9.244829674,-8.679515816,-6.862942652,-2.2879284490000003,-12.367927551269531,-9.258517265319824,-11.65892505645752,-13.685524940490723,-10.306041717529297 -3381,3381,R202A,0.01412703,-0.000811593,-0.005240613,-0.02549675,-0.08994603400000001,0.040802496,-0.003522963,0.031777022,0.0072043409999999995,-0.004250396,0.00262721,0.004093616,-0.014574841000000002,-0.031601969,-0.019391531,-0.09381667199999999,-0.086075396,1.25470461,2.245114357,-3.143709715,-3.393623505,-2.470641785,-3.194128731,-3.2261126019999997,-3.4340419539999996,-3.5962210669999997,-2.359906498,-8.68087387084961,-10.672067642211914,-10.325756072998047,-10.255300521850586,-11.933891296386719 -3382,3382,R202C,0.006926441,-0.050696322,0.000581859,-0.010223511,-0.408126146,0.058954520999999996,-0.0018844999999999999,0.015737382,0.07982787,-0.018175298,-0.083217346,-0.035212167999999995,0.036375886,-0.0062069080000000006,-0.014240113,-0.253535791,-0.5627165,1.416430235,2.051316254,-5.566402192999999,-4.96781855,-4.8644205860000005,-8.126653206,-5.075690346,-4.797428276000001,-4.566229375,-1.512302667,-8.738028526306152,-11.030617713928223,-8.28748893737793,-9.351214408874512,-10.7896728515625 -3383,3383,R202E,-0.0154208,0.054178754,0.035395489,0.055632887,-0.795980403,0.081401893,0.023731557,-0.054573156,0.016449105,0.024734857000000002,0.08362265099999999,0.007460965999999999,0.063330012,0.03326819,0.07799758400000001,-0.516176957,-1.075783849,0.683549567,1.430067376,-5.125272863999999,-4.620369392,-6.0775670470000005,-5.316691276999999,-4.090544502,-5.5211921010000005,-5.687659357,-5.009680595,-10.195390701293945,-10.970141410827637,-9.678500175476074,-11.697927474975586,-11.800485610961914 -3384,3384,R202D,-0.030420987000000003,0.018399312,-0.267550214,-1.7786013459999999,-2.503355296,0.060336771,0.004416127,-0.065258101,-0.036788382,0.034709447000000004,0.0020891770000000002,-0.166824492,-0.368275936,-1.741523432,-1.8156792590000002,-2.660499191,-2.346211401,1.010177622,0.70230544,-6.606283137999999,-4.8410265269999995,-7.010227173,-7.2047932889999995,-6.05703141,-7.918337287999999,-6.190203611,-2.690020938,-12.028620719909668,-14.101274490356445,-12.83357048034668,-13.181795120239258,-14.009504318237305 -3385,3385,R202G,0.011607758000000001,0.002257947,-0.004669171,0.024751007000000002,-0.6735225,0.077376177,0.017229799,0.005985717,-0.005079558,0.001114177,0.0034017170000000003,-0.013861317,0.004522976,-0.004447073,0.05394908599999999,-0.505861574,-0.841183425,1.183847163,1.634563121,-4.948853743,-3.646416641,-5.11080011,-5.81868956,-4.664818657,-5.503543747,-4.912314148,-3.200783654,-10.259268760681152,-11.270395278930664,-10.460041046142578,-9.807403564453125,-11.394424438476562 -3386,3386,R202F,-0.022245763999999998,-0.057054902000000005,0.031047635,-1.334794474,-2.154417167,0.019867033,0.003350029,-0.04784155599999999,-0.05531621900000001,-0.042482571,-0.071627233,0.046700584,0.015394685,-1.1849213140000001,-1.484667634,-1.876098992,-2.432735341,2.657613778,1.878963964,-9.169605334,-7.242079352999999,-7.613571587000001,-12.53218848,-8.225723801000001,-10.23446345,-6.1067378020000005,-4.441405817,-13.832807540893555,-15.755334854125977,-12.930994987487793,-13.330802917480469,-14.19137191772461 -3387,3387,R202I,-0.043907101,0.093036045,-0.013478811,0.12176351,-1.284960855,0.097353712,0.00643359,-0.094247792,-0.036102293,0.150102866,0.035969223,0.120219857,-0.147177479,0.137654398,0.105872621,-0.847585835,-1.722335875,0.420078286,1.3380693259999998,-7.31711071,-6.522624886,-8.191107018,-8.09058799,-6.342393509,-7.438840149,-6.846519519,-5.937942989,-12.792104721069336,-12.895722389221191,-11.153247833251953,-12.718917846679688,-13.468110084533691 -3388,3388,R202H,-0.02993092,0.0029465859999999997,-0.004596067,0.037142847,-1.331543416,0.04904212,0.058164222,-0.118026061,0.013199948000000001,-0.032721776,0.038614947000000004,-0.015418448999999999,0.006226316,0.033113832,0.041171862000000004,-1.155349213,-1.507737619,0.666225592,1.338910085,-5.483851369,-4.111887909,-5.52233046,-6.865654342999999,-5.221072975,-5.698311157000001,-5.838667847000001,-3.2260564869999997,-7.6820292472839355,-9.252458572387695,-7.612083435058594,-7.4968342781066895,-8.144275665283203 -3389,3389,R202K,-0.096902314,-0.051238245,-0.021766922999999997,0.015281343999999999,-0.042276035,0.02085543,-0.018707428999999998,-0.175097198,0.011375178,-0.051009294000000004,-0.05146719599999999,-0.077754846,0.034221001,-0.039212684,0.069775372,-0.024038404,-0.060513665,1.2941672290000001,2.486212468,-2.422831239,-1.1089911190000001,-3.492876663,-3.9416515430000003,-1.7937369230000002,-1.776899948,-3.75523613,-2.27604613,-6.8226423263549805,-6.760257720947266,-4.499103546142578,-6.739382266998291,-7.460407733917236 -3390,3390,R202M,-0.044682358,-0.030387697,-0.032367162000000005,-0.013713747,-0.8584954359999999,0.066653431,-0.043191797000000004,-0.04617291900000001,-0.06049033,-0.000389975,-0.060385417999999996,-0.030751808999999998,-0.033982515,0.007771079,-0.035198572000000004,-0.699078097,-1.017912774,0.659798511,1.3888880630000002,-7.316168536,-6.8467518620000005,-7.925272644,-8.391896332,-6.735524017,-6.6813978270000005,-7.172639258999999,-5.824200377,-12.993839263916016,-12.78317928314209,-11.011605262756348,-11.768257141113281,-13.08814811706543 -3391,3391,R202L,-0.021061742999999997,-0.014458604,-0.008090436999999999,-0.00638522,-1.542524433,0.06586951099999999,0.014186502,-0.056309988,-0.024472485,-0.024889261,-0.0040279470000000005,-0.054630085,0.038449212,-0.065750314,0.052979875,-1.5365244830000002,-1.5485243819999999,0.7400946709999999,1.3224086609999999,-4.978351216,-5.086270103,-5.26750959,-6.302969719,-3.755172295,-4.479834373,-4.893438468,-3.618671373,-12.71906852722168,-12.431541442871094,-10.52066707611084,-12.071786880493164,-12.617668151855469 -3392,3392,R202N,-0.071425063,0.033159054,-0.026066332,-0.032485634,-1.1257120040000002,0.07004442799999999,0.004014958,-0.146865084,0.020111942,0.040355628,0.025962479,-0.051371691,-0.000760972,-0.097031576,0.032060309,-1.025953446,-1.225470562,1.1274939590000002,1.435877865,-6.624979776,-4.916043961000001,-7.356681992,-8.128961685,-5.716518875,-7.0066923679999995,-5.8422385629999996,-3.77373789,-9.60556697845459,-10.369390487670898,-9.470731735229492,-9.874736785888672,-10.487751960754395 -3393,3393,R202Q,-0.051652413,0.015231446000000001,0.012189075,0.06943881,0.057127195,0.060328115999999994,-0.001253854,-0.10205097099999999,-0.001468039,0.030513691000000003,-5.08e-05,0.055108040999999997,-0.030729892,0.09684502,0.042032599999999996,0.067910187,0.046344202,1.145901112,2.997685945,-1.0078154190000002,-0.904976227,-1.662644363,-0.877229774,-0.780896545,-0.813330185,-1.251869208,-2.1452390830000003,-7.528103828430176,-7.337625503540039,-4.9492716789245605,-6.338099479675293,-7.311544418334961 -3394,3394,R202P,-0.023292233,-0.12355947,-1.3973286459999998,-2.156212099,-2.418157231,0.068733222,-0.012480873,-0.034103593,-0.019879952,-0.067160867,-0.179958073,-1.460639711,-1.334017581,-2.2582056759999998,-2.054218521,-2.411264641,-2.425049821,1.065967675,0.08710478699999999,-8.711130405,-7.518736511,-8.668003113,-9.953651321,-8.313440643,-9.101820435,-7.357731992000001,-6.2391923579999995,-13.459611892700195,-16.19870948791504,-11.934090614318848,-12.702670097351074,-14.083382606506348 -3395,3395,R202S,0.0037588590000000002,-0.007672941,-0.024271495,0.028694031000000002,-0.014030269,-0.008757108000000001,-0.021484748999999997,0.029002467,-0.01161889,0.013851291000000002,-0.029197172999999996,0.0037107359999999996,-0.052253725,0.027214171000000002,0.03017389,0.032641269,-0.060701806,1.2554882040000002,2.703136383,-3.781878111,-3.601074783,-3.083462425,-5.03497628,-3.562832382,-3.627044685,-4.265002482,-1.328426158,-7.080743789672852,-9.727412223815918,-8.60372257232666,-8.77804946899414,-9.476347923278809 -3396,3396,R202T,0.050548777,0.005683138000000001,0.020885276,0.046270422,0.00892554,-0.017228356,0.028174107,0.072923447,0.0006223,0.025754604,-0.014388328,0.030247961,0.011522591,0.069065661,0.023475182,-0.0018610089999999998,0.019712088,1.16690635,2.709238972,-4.164589081,-4.599557068,-4.254107552,-5.118462105,-3.998667336,-2.8521513439999997,-3.917276668,-1.290255895,-8.638345718383789,-8.789657592773438,-9.325827598571777,-9.75069522857666,-10.786020278930664 -3397,3397,R202W,-0.013977276,0.0056657769999999994,0.022085437000000003,-1.296770303,-1.8199536530000002,0.064905163,-0.001425075,-0.026529476,-0.016357345,-0.014804226,0.026135778999999998,-0.039763359,0.083934232,-1.232345964,-1.361194641,-1.943045781,-1.696861524,2.786717393,1.944826365,-9.572027321,-7.800009032999999,-8.90658329,-11.88532306,-8.834569626,-10.433651600000001,-7.96267538,-6.646083331,-12.285751342773438,-15.300970077514648,-12.670442581176758,-12.17740535736084,-11.874348640441895 -3398,3398,R202V,0.051220642999999996,0.025211981,0.027117562,0.064059265,-0.350332115,0.045431757,0.056369128,0.046072157,-0.020021501,-0.005074795,0.055498755999999996,0.023632812000000003,0.030602311,0.036729349,0.09138918,-0.293640805,-0.40702342399999997,1.5423954469999999,2.114257004,-6.368198099,-6.174617279,-7.338235451,-6.935490776,-5.815925377,-5.576721611,-6.061554855,-5.1540494180000005,-11.610878944396973,-11.957444190979004,-10.412330627441406,-12.234965324401855,-13.76106071472168 -3399,3399,R202Y,-0.035421283,-0.07277083599999999,-0.015233298999999999,-0.115584596,-1.6885561080000002,0.041978715,0.035309901,-0.106152466,-0.035929025,-0.08203182,-0.063509852,-0.058960567,0.028493968999999997,-0.096448649,-0.134720542,-1.954229948,-1.4228822680000002,1.022293024,1.312197351,-9.124646787,-6.233295227,-8.959063087,-12.34860015,-8.319675156,-9.762600311,-6.397831888,-3.317259661,-10.721026420593262,-13.410184860229492,-10.62374496459961,-11.211014747619629,-11.980268478393555 -3400,3400,Q203A,0.009047373000000001,-0.08521632300000001,-0.06072866,-0.054389064,-0.133863722,0.033598062000000005,-0.003634285,0.02172903,-0.007569052,-0.101486249,-0.068946396,-0.09474456699999999,-0.026712752000000003,-0.11475513,0.0059770019999999995,-0.177008959,-0.090718485,1.4935933769999998,2.194152543,-0.8910614990000001,-1.131567566,-0.6918096690000001,-0.421077614,-0.38278298200000005,-1.828069664,-2.817035642,0.932136052,-4.263880252838135,-5.141622066497803,-4.911391258239746,-5.084702014923096,-5.0468668937683105 -3401,3401,Q203C,-0.013707403,-0.130153166,-0.082641422,-0.074973065,-0.363158022,0.003662383,-0.018307791,-0.009107015,0.06219104599999999,-0.155197969,-0.10510836300000001,-0.198538678,0.033255834,-0.18838121100000002,0.038435082,-0.38079633799999996,-0.34551970600000004,1.943210211,2.2745883030000003,-5.966348708,-6.534026122999999,-6.0253395770000004,-5.377712235,-5.32257222,-6.5720933839999995,-7.118625797999999,-4.394582485,-9.938577651977539,-10.940593719482422,-11.011190414428711,-10.789525985717773,-10.632980346679688 -3402,3402,Q203E,-0.02997642,-0.079687865,-0.080524006,-0.06036529,-0.111883842,0.045276058,-0.036334364,-0.023618475,0.034983566,-0.053542850999999995,-0.105832878,-0.11070182099999999,-0.050346191,-0.11877780800000001,-0.0019527720000000002,-0.124756862,-0.099010822,1.506535559,2.276828753,-1.003602013,-1.036028091,-1.481996605,-0.682539375,-0.219239693,-1.598206299,-3.183675062,0.658194204,-4.114530563354492,-4.794034957885742,-4.890763282775879,-5.625893592834473,-5.714317321777344 -3403,3403,Q203D,0.080964106,-0.042763964,-0.02043459,-0.031599992,-0.137649048,0.045961942,0.131839123,0.030089087999999996,-0.008348654,-0.108022985,0.022495058,-0.097488314,0.056619135,-0.088460669,0.025260685,-0.21394192,-0.061356175,1.4623523719999998,2.102074146,-1.799307455,-2.019856232,-2.229813545,-1.52509304,-1.051295441,-2.170479019,-3.713644791,0.574432036,-4.268775463104248,-5.773844242095947,-5.941792011260986,-7.390829086303711,-6.715688228607178 -3404,3404,Q203G,0.036486837,-0.054660442999999996,-0.035741373,-0.018183958,-0.131112702,0.064790188,0.030634425,0.042339247999999996,-0.029020185,-0.07803711099999999,-0.031283774,-0.082384597,0.010901851,-0.073290164,0.036922248,-0.16364900400000001,-0.0985764,1.1849613209999998,1.959597826,-3.170589035,-3.94040535,-2.758094017,-2.669244461,-2.548363487,-3.93683786,-4.520227665,-1.3195342159999999,-6.202154636383057,-7.016197204589844,-7.120766639709473,-7.17852783203125,-6.93220329284668 -3405,3405,Q203F,0.050775695,0.057530164,0.05819209400000001,0.149591527,-0.6362545039999999,0.127188514,0.05996154,0.04158985,-0.161438857,0.127578833,-0.012518505,-0.032898229,0.149282417,0.10906825699999999,0.190114796,-0.535017581,-0.737491426,0.574247118,1.3994547830000001,-6.233446756,-6.736341515,-6.103628098,-6.073323296,-4.997184792,-7.256756081,-6.872597431,-4.431291731,-9.457783699035645,-11.011820793151855,-10.108354568481445,-9.925678253173828,-10.558927536010742 -3406,3406,Q203I,0.033669049,-0.150967654,-0.098661745,-0.091308999,-0.14345360199999999,0.083693169,0.021776978,0.045561119000000004,-0.041158311,-0.223818342,-0.078116965,-0.231767077,0.034443588,-0.170242489,-0.012375509,-0.24432454899999997,-0.042582655,1.661575686,2.183431724,-4.250835226,-4.97158136,-4.244836739,-4.478042816,-3.4337146610000002,-4.126000557,-5.24660358,-3.016086192,-7.953697681427002,-9.318394660949707,-8.01759147644043,-7.536952972412109,-8.186853408813477 -3407,3407,Q203H,0.143710879,-0.040920946,-0.049029882000000004,-0.020392405,-0.10444893400000001,-0.012674969,0.141499942,0.145921816,0.006565066,-0.14352738199999998,0.061685490999999995,-0.181579989,0.083520226,-0.12293714900000001,0.08215234,-0.22785947199999998,0.018961604,1.82105828,2.3667080780000003,-3.055767175,-4.264850128,-2.8118556210000003,-2.532133087,-2.351622353,-3.318374687,-4.773509707,-2.074518811,-5.686776161193848,-6.735072612762451,-6.8379292488098145,-6.185570240020752,-6.527352809906006 -3408,3408,Q203K,0.074298141,-0.118643304,-0.012686892,-0.021654338999999998,-0.062261928,-0.043195069,0.053122115,0.095474167,0.010777712,-0.208361391,-0.028925217000000003,-0.09829256300000001,0.07291878,-0.067150604,0.023841927000000002,-0.088274745,-0.036249111,1.23689761,2.201551701,-1.064063065,-1.548339577,-0.986165359,-0.822657669,-0.818102448,-1.14505027,-2.543776781,-0.338444146,-4.465851306915283,-4.526482105255127,-4.508301258087158,-4.303238391876221,-3.6017165184020996 -3409,3409,Q203M,0.104041635,-0.10142385599999999,0.012983266,-5.21e-05,-0.063881637,-0.044808457999999995,0.084320886,0.123762384,-0.011426431,-0.066096066,-0.136751645,-0.18649049399999998,0.212457025,-0.104792162,0.104687865,-0.09349272800000001,-0.034270545,1.4613129390000001,2.305370451,-4.9914325999999996,-5.667575348,-4.797605606,-5.006145424,-4.248336838,-5.237499786,-5.779285241,-3.7721852910000004,-7.388789176940918,-8.395650863647461,-7.771901607513428,-7.628384590148926,-7.693488597869873 -3410,3410,Q203L,0.076733229,-0.019976816,-0.040596634,-0.012936268999999999,-0.16289009,0.056638306,0.077877896,0.075588562,-0.013868166999999999,-0.042928201,0.0029745690000000003,-0.08576751099999999,0.0045742429999999995,-0.087221597,0.06134906,-0.215131689,-0.11064849,1.806083444,2.414225014,-3.093569086,-4.157415283,-2.873141525,-3.2488523789999997,-2.163959915,-3.0244763260000003,-4.965731275,-1.687776709,-6.754018783569336,-7.49875545501709,-6.79116678237915,-6.744150638580322,-6.8295722007751465 -3411,3411,Q203N,-0.025825347999999998,-0.10109359400000001,-0.137055663,-0.032697742,-0.171366942,-0.02901663,0.034154276000000004,-0.085804972,-0.097281544,-0.042928201,-0.159258986,-0.234038893,-0.040072433,-0.047009061,-0.018386422,-0.17166599600000002,-0.171067888,1.441922423,2.16962819,-2.46831196,-3.4037969439999998,-2.703369385,-2.8656972730000003,-1.4302223969999999,-1.938473801,-4.05033993,-1.015616292,-4.630174160003662,-5.9041900634765625,-5.422208309173584,-6.295449256896973,-5.61141300201416 -3412,3412,Q203P,0.033892855,-0.066447601,-0.8554704,-2.029098576,-3.0028038610000003,0.065592161,0.036041841,0.031743868,-0.015156833,-0.123412189,-0.009483013,-1.00036777,-0.71057303,-2.041458198,-2.016738954,-2.733961023,-3.2716466989999997,2.202035548,0.8773569,-5.781249252,-6.24758445,-5.815714127000001,-5.790782326,-5.007389862,-6.044775497000001,-7.283458106,-4.435527223,-9.168648719787598,-11.709588050842285,-9.195960998535156,-9.798198699951172,-10.659141540527344 -3413,3413,Q203S,0.027661214,-0.081439249,-0.059361664,-0.042615,-0.125549632,0.082725732,0.024483148,0.03083928,0.036195813,-0.087182804,-0.075695693,-0.112288488,-0.006434839,-0.101622115,0.016392115,-0.17601123800000001,-0.075088025,1.61032494,2.277288853,-2.337544208,-3.2307641910000005,-2.30539698,-1.9935813830000002,-1.7107478409999999,-2.4472306440000002,-4.209973258,-0.893976655,-4.980074405670166,-5.887547016143799,-5.811775207519531,-6.058406352996826,-5.639293670654297 -3414,3414,Q203R,0.047367775,-0.058564477999999996,-0.040398525,-0.01271324,-0.093200959,0.028179235,0.053573617000000004,0.041161932000000005,0.009154381999999999,-0.089068291,-0.028060664,-0.080336694,-0.000460355,-0.080521078,0.055094598,-0.130930249,-0.055471667999999995,1.5154231740000002,2.322853491,-1.240930949,-1.7690986180000001,-0.943542236,-0.841148483,-0.944216743,-1.706648666,-2.0736871619999997,-0.14894945,-4.952942848205566,-5.522675514221191,-5.5613179206848145,-4.748769760131836,-4.5904011726379395 -3415,3415,Q203T,0.016846408,-0.09639090800000001,-0.061456975999999996,-0.036453177,-0.08307937,0.06500030799999999,0.002246743,0.031446073,0.022963702000000003,-0.098486401,-0.09429541400000001,-0.127135989,0.0042220370000000005,-0.082686555,0.009780202,-0.141026881,-0.025131857999999997,1.473926935,2.233998799,-2.203119624,-2.575669037,-2.314930153,-1.7355641169999998,-1.900156723,-2.489278091,-3.804767317,-0.7283879320000001,-5.053798675537109,-5.663582801818848,-5.309125900268555,-5.461788177490234,-5.486702919006348 -3416,3416,Q203W,0.017704225,-0.093253845,-0.046018769,-0.026184829,-0.56026314,0.072701963,0.013263212,0.022145237,-0.069141378,-0.100766478,-0.085741211,-0.122836911,0.030799373999999997,-0.10973053199999999,0.057360874000000006,-0.42296483100000004,-0.6975614490000001,1.7951431480000002,2.143910843,-6.174567584,-6.76061937,-6.009993065,-5.58639698,-5.584800995,-6.931027512000001,-6.556441515,-4.693252337,-9.819005012512207,-11.578898429870605,-11.041284561157227,-11.012248992919922,-10.7373046875 -3417,3417,Q203V,0.045013014000000004,-0.020803282,-0.022407666,-0.019157165,-0.13953731,0.030298033999999998,0.050029845999999996,0.039996181,-0.008545371999999999,-0.016748525,-0.024858039,-0.06669460099999999,0.02187927,-0.073341203,0.035026874,-0.155023727,-0.12405089300000001,1.4744347880000002,2.227591337,-3.972264169,-4.522452782,-3.9161108319999998,-3.894717445,-3.3375336069999997,-4.19050618,-4.717166703999999,-2.5633544219999997,-6.9890971183776855,-8.446541786193848,-7.30208683013916,-7.030852794647217,-7.267221927642822 -3418,3418,Q203Y,0.005231051,-0.167024505,-0.025025798,-0.042903345999999995,-0.32455408,0.076706627,-0.040617851,0.051079953,-0.073642058,-0.18905623600000002,-0.144992774,-0.111574775,0.06152318,-0.132139639,0.046332947,-0.35948346700000006,-0.289624692,1.9660923590000001,2.348822776,-5.962945792999999,-6.675343162999999,-5.88945314,-5.817266281,-4.9687962489999995,-6.463870132,-7.136570454,-4.399146897,-8.462112426757812,-10.338621139526367,-9.275259017944336,-9.267376899719238,-9.989677429199219 -3419,3419,Q204A,-0.009730886999999999,-0.024993151,-0.049539253,-0.034237914,-0.102016433,0.032298903,0.023037468,-0.042499242,-0.040804684,-0.077199885,0.027213584,-0.097871906,-0.001206599,-0.079614709,0.011138882,-0.142703424,-0.061329441,1.51423015,2.284770403,-6.928385054,-5.896941315,-7.806191856,-6.556190086,-8.14611496,-6.236487052999999,-6.995307368,-1.389158577,-8.136701583862305,-8.80856704711914,-9.47719669342041,-9.85977554321289,-9.675440788269043 -3420,3420,Q204C,-0.020765872,0.029843336,-0.012705596999999999,0.076884177,-0.043050656,0.050648317000000005,-0.0072566919999999995,-0.034275052,-0.055255463,0.059440562,0.00024611,0.023202255,-0.048613449,0.130708091,0.023060262999999998,0.02928292,-0.11538423099999999,1.0639854640000002,2.8075129530000003,-10.26420583,-9.689733711,-10.22784941,-9.631563437999999,-12.12607321,-9.645809364,-8.537906429,-5.379497447,-10.606135368347168,-11.551851272583008,-11.407612800598145,-12.421525001525879,-11.13469409942627 -3421,3421,Q204E,-0.032467208,-0.005834331,-0.033789291,-0.045914631,-0.04927128099999999,-0.01833168,0.00912238,-0.074056796,-0.07496675900000001,-0.02538629,0.013717628999999999,-0.04742465,-0.020153932,-0.0444736,-0.047355662,-0.067357532,-0.03118503,1.288020487,2.3155706240000002,-4.793254344,-4.273599579,-6.029192977999999,-4.62771769,-5.415277351,-3.620484123,-6.621755222999999,-0.828970683,-7.263723850250244,-6.828423023223877,-8.23179817199707,-7.436417102813721,-9.431365013122559 -3422,3422,Q204D,-0.072188449,0.032241165,-0.009304158,-0.008682049,-0.441077459,0.07291431,-0.026080016,-0.11829688099999999,-0.074933015,-0.025450012,0.089932341,-0.009273544,-0.009334772,-0.024741816,0.007377718,-0.313380434,-0.568774484,1.142910796,1.76653607,-9.718823666,-9.903390457,-11.3989586,-7.914471497,-12.77802245,-6.599275322,-7.317098519,-2.7555048039999996,-9.256097793579102,-9.324954986572266,-10.204351425170898,-10.26296615600586,-11.926065444946289 -3423,3423,Q204G,-0.037548672000000005,-0.028265931,-0.035292868,-0.177222968,-1.7868700880000001,0.10295553,-0.0049419220000000005,-0.070155421,-0.11241191800000001,-0.056335465999999994,-0.000196396,-0.070790954,0.00020521799999999999,-0.156718257,-0.197727679,-1.673550461,-1.9001897140000001,1.154406569,1.3506297630000001,-10.35932461,-9.756956596,-10.26896438,-10.12925534,-11.86313744,-9.778309303,-7.9674092839999995,-4.219445045,-9.650835037231445,-11.010065078735352,-11.670068740844727,-11.993918418884277,-12.183348655700684 -3424,3424,Q204F,-0.006789703,0.026093242000000003,-0.051287222,0.01939235,-0.770665464,0.08903114599999999,-0.000523309,-0.013056097,-0.129343457,-0.036907033,0.089093516,-0.05473879,-0.047835654000000005,-0.012382908,0.051167607999999996,-0.592134035,-0.949196892,0.965988554,1.490980685,-8.206986012,-7.236257515,-7.038316292,-5.875154564,-10.38010383,-10.50509786,-6.15695264,-0.771724835,-9.869293212890625,-7.346920013427734,-8.676228523254395,-9.897500038146973,-10.038046836853027 -3425,3425,Q204I,0.041960461,0.006712298,0.021066124,0.042673057,0.012872343,0.050409503,0.08377113900000001,0.00014978299999999999,-0.077982089,0.061396217999999995,-0.047971623,-0.014086461000000002,0.056218708,0.043905485999999994,0.041440628,-0.024057198,0.049801883,1.299156972,2.629359607,-6.326507518,-5.364922058,-7.192080353,-6.309971375,-8.456743675,-4.308820129,-4.908510103,-1.8229333509999999,-8.152167320251465,-8.270278930664062,-6.343356609344482,-8.577202796936035,-7.342283248901367 -3426,3426,Q204H,-0.026674787000000002,-0.0010766880000000001,-0.043184657,0.026326247999999997,-0.08535206,-0.012439457,-0.020613442,-0.032736132,-0.065528893,-0.017685659,0.015532283999999999,-0.008474308,-0.077895006,0.045499927,0.007152569,-0.044454435,-0.126249684,1.2125215329999999,2.547673376,-5.323970877,-5.303025703,-4.649339287,-3.8360319439999997,-5.896350845,-6.935106606000001,-5.174337541,-2.627184904,-7.641334056854248,-7.482834815979004,-7.577472686767578,-9.110779762268066,-8.581151962280273 -3427,3427,Q204K,0.006345465,-0.039110271,-0.07272278900000001,-0.028403328,-0.27179529199999997,-0.090846588,0.00156968,0.011121249,-0.134552449,-0.137774199,0.059553657999999995,-0.035164417,-0.110281161,-0.05561704,-0.0011896160000000001,-0.25478571899999997,-0.288804864,1.4490578580000002,2.03521767,-3.149801241,-3.731339188,-2.358207733,-3.491384727,-3.834167542,-2.333907013,-3.8468176030000003,-1.612371369,-7.032352447509766,-8.628835678100586,-8.427835464477539,-8.153685569763184,-8.454654693603516 -3428,3428,Q204M,0.013628903000000001,-0.021238912999999998,0.000480905,-0.049963987,-0.027101503,-0.03954068,0.030497981,-0.003240175,-0.002857593,-0.053638474000000005,0.011160648,-0.020586531,0.02154834,-0.04971548,-0.050212494,-0.030833844,-0.023369161,1.450314855,2.5612840080000003,-6.387218326,-5.610242935,-7.587726112,-5.772013199,-7.918727463,-5.04738192,-6.151981162999999,-2.065276824,-7.796326637268066,-7.4880146980285645,-6.804750442504883,-8.31179141998291,-7.27253532409668 -3429,3429,Q204L,0.007422384000000001,0.004814295,-0.000320769,0.021258806,0.004851927,0.0028440709999999997,0.01424432,0.0006004480000000001,-0.060463376,-0.07468988,0.08431847,-0.022114314,0.021472776000000002,0.0064159230000000005,0.036101689,-0.041269882,0.050973736,1.269526613,2.4815177409999998,-4.711900244,-4.036818321,-5.244483826000001,-4.175625587,-5.9135473560000005,-4.189026131,-3.622523234,-0.21741106699999999,-6.215845108032227,-5.662759780883789,-6.138676166534424,-6.02656364440918,-5.072200298309326 -3430,3430,Q204N,-0.02479313,-0.027897848,0.035344717000000005,0.07143970200000001,-0.08281981,0.043573272,0.069535032,-0.11912129099999999,-0.075885732,-0.001191481,-0.054604214000000005,0.087150176,-0.016460742,0.09831152900000001,0.044567875,-0.052779095,-0.112860525,1.244192204,2.483465343,-7.790969315,-8.371457451,-7.187158455,-7.62318074,-8.955768379,-6.8172815479999995,-7.789989527,-4.281937966,-9.280049324035645,-9.378926277160645,-9.438070297241211,-10.254841804504395,-10.813515663146973 -3431,3431,Q204P,-0.031377557,-0.001233738,-0.188287951,-1.734230786,-2.3246162999999997,0.143612099,0.014259436,-0.07701455,-0.110958578,-0.039322457000000005,0.036854982,-0.196021898,-0.180554004,-1.6661916959999998,-1.802269876,-2.151656955,-2.497575645,1.2615516420000001,0.7458076029999999,-9.012237086,-8.522665092,-9.101436501,-7.67965802,-10.08138094,-9.676044884,-7.314275267,-3.6255577010000004,-11.267295837402344,-10.241778373718262,-11.797165870666504,-10.65568733215332,-11.198389053344727 -3432,3432,Q204S,-0.020187171,0.001088683,-0.01489269,0.036134282000000004,-0.18684614800000002,0.012153545,-0.000267164,-0.040107178,-0.086292106,-0.037127291,0.039304656,-0.008168789000000001,-0.02161659,0.049350468,0.022918095,-0.160845207,-0.21284708800000002,1.310114585,2.176296874,-7.599155696,-6.9609521029999994,-7.979813316,-7.077667099,-9.411826927,-6.565519035,-7.4839749310000006,-3.277965501,-8.112744331359863,-8.979286193847656,-9.307806015014648,-10.039816856384277,-9.493858337402344 -3433,3433,Q204R,-0.021702945,-0.00139804,-0.064459337,-0.013331497,-0.115500466,0.084304336,0.011473048999999999,-0.054878937999999995,-0.059994199000000005,-0.05537413,0.052578050999999994,-0.09796157400000001,-0.030957099,-0.032208554,0.00554556,-0.11828094199999999,-0.11271999,1.404742944,2.264955788,-3.980964052,-4.157758018,-3.682695976,-3.281483986,-4.705201057,-4.077681221000001,-4.520942915,-0.138971398,-6.473621368408203,-8.692785263061523,-8.014934539794922,-7.908548355102539,-7.540825366973877 -3434,3434,Q204T,-0.011209562,-0.009830137,-0.070173495,-0.052257522,-0.056559810999999995,-0.034811822,0.005040955,-0.027460078,-0.04017235,-0.034790037999999995,0.015129763999999999,-0.098250134,-0.042096855999999995,-0.026179085,-0.07833595900000001,-0.077834206,-0.035285416,1.223787824,2.207505222,-5.288090616,-4.037604362,-6.353929657,-5.75799514,-6.227979462,-4.0629444580000005,-4.794205527,-1.840653195,-7.280570030212402,-7.692296028137207,-6.936242580413818,-8.495038986206055,-8.319011688232422 -3435,3435,Q204W,-0.028799862000000002,-0.042011687,-0.041096952,-0.03338423,-1.247783737,0.11490595599999999,0.021776474,-0.079376198,-0.154134722,-0.063901217,-0.020122156999999998,-0.090569835,0.008375931,-0.04984088,-0.01692758,-0.993601002,-1.5019664719999999,1.392301564,1.544910084,-8.559796611,-8.915647606,-7.728343636,-5.590786774,-10.61903686,-9.945168182,-7.1008555829999995,-2.406676212,-10.524024963378906,-9.827449798583984,-11.10318374633789,-12.383489608764648,-10.588526725769043 -3436,3436,Q204V,0.005264583000000001,0.021071642999999998,-0.029116932,0.008258363000000001,-0.041599533,-0.014870648,0.035987305,-0.025458138999999998,-0.08610704300000001,-0.005590092,0.047733378,-0.039594362,-0.018639501,0.013785725,0.002731001,-0.033584791,-0.04961427400000001,1.271114357,2.630115111,-6.961271057,-5.660403587,-8.026576248,-6.411172775,-9.208332321,-5.499870354,-6.137435554,-1.6237079380000001,-8.370299339294434,-8.715232849121094,-8.131526947021484,-8.874972343444824,-8.674958229064941 -3437,3437,Q204Y,0.07924761799999999,-0.014098208999999999,-0.0087085,-0.009405432,-0.310308743,0.008972584,0.116684812,0.041810423,-0.064618127,-0.174903038,0.14670662,-0.080519597,0.063102598,-0.032792512999999995,0.01398165,-0.414486562,-0.206130924,1.2620928009999999,1.737657267,-7.758536011,-7.3733314210000005,-5.261333893,-6.9089653239999995,-9.320110069,-9.928939346,-6.29015821,-1.889148187,-9.928157806396484,-6.036127090454102,-8.734618186950684,-10.649208068847656,-10.125138282775879 -3438,3438,L205A,0.019851063000000002,-0.015396981,-0.034639964,-1.658049225,-2.461863376,0.04322961,-0.010479931999999999,0.050182057,-0.069597491,-0.013703185,-0.017090776000000002,-0.06811091,-0.001169017,-1.670185323,-1.645913126,-2.333458432,-2.59026832,0.9366132290000001,0.706922305,-12.20451401,-12.36238978,-12.652662699999999,-10.13373679,-9.627166245,-16.24661452,-6.090057057999999,-2.594446156,-11.1917085647583,-10.702859878540039,-11.727926254272461,-12.377641677856445,-11.850630760192871 -3439,3439,L205C,-0.019895716,-0.000569618,-0.054033073,-1.836800564,-2.875775708,0.003212922,-0.05668269,0.016891258,-0.030231242000000002,0.024367813999999998,-0.025507049,-0.046141259000000004,-0.061924887000000005,-1.8532546000000003,-1.8203465269999999,-2.8857435660000004,-2.865807849,0.66464182,0.673460125,-11.4146319,-13.57925574,-11.01678369,-10.85272196,-8.69694928,-12.92744884,-8.043977132,-5.2450627,-12.374463081359863,-12.026061058044434,-11.910735130310059,-12.760991096496582,-13.571173667907715 -3440,3440,L205E,0.0066945730000000005,0.031572172999999995,-1.108244013,-2.3257169980000003,-2.7855108960000003,0.017666524,-0.001568135,0.014957281000000001,-0.06349039,0.062592862,0.000551484,-1.1722083559999998,-1.04427967,-2.1738963609999997,-2.477537635,-2.650082827,-2.920938965,0.569892665,0.08209052,-14.78454096,-15.90706487,-14.51110901,-13.48524332,-12.62438112,-17.39490649,-10.27267504,-10.18488361,-15.786518096923828,-15.616522789001465,-14.789304733276367,-15.835762023925781,-16.483394622802734 -3441,3441,L205D,0.057195529,-1.082538258,-2.3786963869999997,-2.665103682,-2.7269575710000002,0.025724287999999998,0.065306561,0.049084497000000005,-0.005336975999999999,-1.263456643,-0.901619873,-2.42047082,-2.336921953,-2.4051254859999998,-2.9250818780000003,-2.4833719430000003,-2.9705431989999997,0.297380981,-0.7756981829999999,-14.92006315,-16.33820818,-14.68664388,-13.79396,-12.1979035,-17.58360016,-10.27267504,-10.18488361,-17.312301635742188,-17.023250579833984,-17.12187957763672,-17.32760238647461,-18.330890655517578 -3442,3442,L205G,-0.004659702,-0.614059644,-2.0709843269999997,-2.479275907,-2.949099702,0.02923512,-0.0038648370000000003,-0.005454567,0.011988781,-0.594613098,-0.633506189,-2.095738725,-2.0462299280000003,-2.36918893,-2.589362883,-2.661315207,-3.236884196,1.09562683,-0.303195952,-12.82780751,-14.37696815,-12.72808591,-11.78300147,-10.88779417,-14.36318786,-7.6851408260000005,-4.9683388939999995,-15.145116806030273,-15.38531494140625,-15.103743553161621,-17.281265258789062,-16.444721221923828 -3443,3443,L205F,-0.032178969,-0.031868468999999996,-0.024513032,-0.12097301099999999,-1.8710643869999999,0.035709132000000005,-0.015095085,-0.049262852999999995,-0.066830476,-0.02863341,-0.035103527,-0.073118109,0.024092046000000002,-0.197109332,-0.044836689000000006,-1.4714181290000001,-2.2707106440000002,1.312322062,1.403767805,-5.833958481,-5.695153603,-6.216447617,-5.27031443,-5.455759476,-6.5321172789999995,-5.006244164,-2.879872603,-9.037806510925293,-8.918252944946289,-7.09702205657959,-8.418425559997559,-9.276926040649414 -3444,3444,L205I,0.0014169329999999998,0.032587775,-0.015563045,0.037772743,-0.249558421,0.020642222,-0.022556787000000002,0.025390653,-0.005490059,0.048357742999999995,0.016817806,-0.041709645,0.010583556000000001,0.009847861999999999,0.065697623,-0.189220765,-0.309896076,1.3605178759999998,2.106268779,-5.3771602110000005,-5.3503444369999995,-5.300337196,-6.325852157999999,-5.100272621,-4.808994643999999,-5.263339158,-2.010209142,-7.918340682983398,-7.77387809753418,-8.952552795410156,-8.997352600097656,-7.619937896728516 -3445,3445,L205H,0.006892926999999999,-0.365777736,-1.938760469,-2.60437136,-2.728694618,0.007983501,-0.016132122,0.029917975,-0.015007204,-0.35813377399999996,-0.37342169799999997,-2.214117956,-1.663402981,-2.499802618,-2.7089401019999997,-2.7029878110000003,-2.7544014239999997,0.7572956670000001,-0.338846108,-13.85371351,-14.50213554,-13.42364077,-13.16564353,-11.45053887,-16.72660886,-10.27267504,-10.18488361,-14.913726806640625,-15.670672416687012,-13.149219512939453,-14.973987579345703,-15.856489181518555 -3446,3446,L205K,0.00231367,-1.280676373,-2.182737908,-2.531614572,-2.59346846,0.079158584,0.02612741,-0.021500071000000003,-0.085210466,-1.7038005,-0.8575522459999999,-2.161844673,-2.203631142,-2.447529335,-2.615699808,-2.525775791,-2.661161129,-0.06701978900000001,-1.063933208,-14.21506142,-15.45180968,-14.16354399,-13.04528584,-11.473633900000001,-16.94103371,-10.21800695,-9.932737047,-16.713369369506836,-18.249622344970703,-16.524658203125,-17.051210403442383,-16.398967742919922 -3447,3447,L205M,0.010868093999999998,-0.019381352,-0.020774304,-0.036893617999999996,-0.083827633,-0.0063274180000000005,-0.000503402,0.022239589,-0.08645920900000001,-0.065967239,0.027204536,-0.089442508,0.0478939,-0.014511484,-0.059275750999999995,-0.089982887,-0.077672378,1.360942417,2.332839163,-6.1927267939999995,-6.399631874,-4.48518425,-5.423384911,-7.004078995,-7.651353942999999,-5.43290365,-1.160793435,-7.921177864074707,-7.395183086395264,-7.597320556640625,-7.804599285125732,-7.8449907302856445 -3448,3448,L205N,-0.03353555,-0.313474985,-1.813753097,-2.313144758,-2.7640742719999998,0.022149444,-0.002719758,-0.06435134099999999,-0.10782980800000001,-0.305544755,-0.321405215,-1.967708911,-1.659797282,-2.2533935730000003,-2.372895943,-2.632670025,-2.8954785189999996,1.0857587020000001,-0.10720649300000001,-14.18454103,-16.19117523,-13.21128432,-13.359175,-12.20116688,-15.95990372,-10.27267504,-10.18488361,-15.413858413696289,-15.455347061157227,-14.577385902404785,-15.74553394317627,-15.910587310791016 -3449,3449,L205Q,0.022047672999999997,0.10734009900000001,-1.0249948009999998,-2.17490146,-2.7367553489999996,0.025358406,0.005449956,0.03864539,-0.01779787,0.168251663,0.046428534,-0.9755342490000001,-1.074455352,-2.26121891,-2.088584009,-2.816586622,-2.656924076,0.48572669,0.098547005,-13.12990704,-14.51053258,-12.60570457,-12.00533751,-10.48405785,-16.04390269,-9.339040551,-7.654565728,-12.510326385498047,-13.744697570800781,-11.746769905090332,-13.40333366394043,-13.038497924804688 -3450,3450,L205P,-0.000986359,-1.08842056,-2.155942997,-2.368604129,-2.968101119,0.041800187999999995,-0.00689488,0.004922162,0.009150973,-1.268461663,-0.908379457,-2.247406015,-2.064479978,-2.307311634,-2.4298966230000003,-2.807631779,-3.128570458,0.09530552699999999,-0.774392435,-12.94505789,-14.50835458,-13.04197619,-12.28465415,-10.63440548,-14.25589904,-8.205569201,-6.298473446,-16.15811538696289,-16.029430389404297,-13.866484642028809,-17.101694107055664,-14.438264846801758 -3451,3451,L205S,-0.038651277000000005,-0.132195601,-1.4650643209999998,-2.336847929,-3.040917185,0.014375638999999999,-0.039953762000000004,-0.037348791,-0.032442201000000004,-0.070943296,-0.193447905,-1.547736905,-1.382391736,-2.519802444,-2.153893413,-2.966025686,-3.1158086839999997,0.788923095,0.034129325,-14.07678772,-15.98993616,-13.62148308,-13.20527725,-12.21245905,-15.35478309,-9.613457214,-7.633653738,-13.77145004272461,-14.119758605957031,-13.281859397888184,-15.003293991088867,-13.513408660888672 -3452,3452,L205R,-0.024106147,-1.231224138,-2.217487887,-2.2882133,-3.2162640689999997,0.056269062,-0.028128808999999998,-0.020083484,-0.003659815,-1.3946145,-1.067833775,-2.250598681,-2.184377092,-2.0591620880000003,-2.5172645119999997,-2.7394685360000004,-3.693059602,-0.125109224,-0.872408836,-14.32629773,-15.834993599999999,-13.70488641,-13.23032948,-11.46053732,-17.40074187,-10.27267504,-10.18488361,-16.176021575927734,-17.673498153686523,-15.60310173034668,-15.399944305419922,-15.282715797424316 -3453,3453,L205T,-0.026679117000000002,0.015355856000000001,-0.107506054,-1.814054746,-2.364069586,0.025617056000000003,-0.040602574,-0.01275566,-0.042783105,0.046173525,-0.015461813,-0.074705127,-0.14030698,-1.7666362290000002,-1.8614732630000002,-2.462182644,-2.2659565280000002,0.8315045090000001,0.690175068,-12.8851837,-14.61248753,-13.402792499999999,-10.50753795,-11.19986922,-14.70323128,-7.872359776000001,-5.400813818,-11.344642639160156,-11.368840217590332,-11.564370155334473,-11.369132041931152,-10.980385780334473 -3454,3454,L205W,0.01021667,0.011621029,-0.0020935529999999997,-1.460246231,-2.016528177,0.007436162,0.00771002,0.01272332,-0.04668821099999999,0.003853154,0.019388903,-0.05220217,0.048015064,-1.291182134,-1.6293103269999998,-2.122756257,-1.9103000959999998,2.349978198,1.5167870730000002,-10.209028199999999,-10.0729953,-9.377304054,-9.86591153,-8.791057692999999,-12.93787243,-7.710166673,-6.29847324,-12.860475540161133,-13.261041641235352,-11.261548042297363,-13.00839900970459,-13.340665817260742 -3455,3455,L205V,-0.033243199999999994,-0.031755667,-0.0050245409999999996,-0.016427207,-1.66022784,0.025295441000000002,-0.023272667,-0.043213732000000005,-0.068674316,-0.046293803,-0.017217531,-0.033196775,0.023147692999999997,-0.009280786999999999,-0.023573627000000003,-1.567239099,-1.75321658,0.6128761979999999,1.312323321,-8.101881889,-8.814419838,-8.375038361,-7.816889626,-7.402509628,-8.100551994,-5.5651819389999995,-2.22406891,-7.930983543395996,-9.021617889404297,-9.067532539367676,-9.046911239624023,-7.971450328826904 -3456,3456,L205Y,-0.016686586,-0.0447879,-1.180967069,-2.772704446,-2.834558335,0.07702672099999999,0.024838462999999998,-0.058211634000000005,-0.102939233,-0.055303054000000004,-0.034272746,-1.124362061,-1.237572077,-2.665319228,-2.8800896639999998,-2.7435656839999996,-2.925550986,0.8841389479999999,0.123134016,-9.771314712999999,-10.02374464,-9.755913681000001,-9.328292686000001,-8.24957164,-11.49905091,-7.396978087999999,-5.64831544,-13.439491271972656,-12.647191047668457,-11.225610733032227,-12.516046524047852,-14.478902816772461 -3457,3457,I206A,0.050049515999999995,-0.021650217000000003,0.003051636,-0.011995618000000001,-0.09558502199999999,-0.035289522999999996,0.058581323,0.041517708,0.03452531,0.022244576000000002,-0.065545009,-0.045044735,0.051148007,-0.002665701,-0.021325535,-0.16640379800000002,-0.024766245,1.604836722,2.37359826,-1.947537602,-1.9467960819999999,-2.6359751819999997,-0.7747465590000001,-1.498135376,-2.882034813,-2.419399341,-1.314093931,-5.4756975173950195,-6.513669013977051,-5.407351970672607,-5.143038272857666,-5.859259128570557 -3458,3458,I206C,0.056276688,-0.016204476000000002,0.02971354,0.00803283,-0.120373889,-0.059680889,0.045955632999999996,0.066597743,0.06031025,0.025042907000000003,-0.057451859,-0.021714567999999997,0.081141648,0.011353924,0.004711735,-0.172991332,-0.067756445,1.3759320680000002,2.17049496,-5.749617516,-4.805214844,-4.552616791,-6.325218597,-6.14028685,-6.924750496000001,-5.5584272960000005,-3.8531741889999997,-8.496282577514648,-8.074596405029297,-8.091423034667969,-8.691386222839355,-8.882734298706055 -3459,3459,I206E,0.005228392,-0.055838723,0.000714687,-0.048548315,-0.46814960299999997,0.080354654,-0.00164332,0.012100103999999999,0.048135572,-0.007976633,-0.103700813,-0.066373716,0.067803089,-0.044947639000000005,-0.05214899,-0.43787154,-0.498427666,1.448778451,1.8568013190000001,-1.8043769790000002,-1.763144585,-1.836326523,-1.464487595,-0.900129005,-3.0577971880000003,-2.866695879,-1.321184706,-6.356667518615723,-7.815593242645264,-5.231575965881348,-5.940127849578857,-8.097981452941895 -3460,3460,I206D,-0.072856554,-0.077987448,-0.036688185,-1.4824601819999998,-2.292964037,0.009224872,-0.09249906599999999,-0.053214042,0.04916144099999999,0.022692186,-0.178667081,-0.031897236,-0.041479133,-1.146509665,-1.818410699,-2.430204099,-2.1557239740000003,0.809928908,0.74630745,-4.533380737,-4.468248474,-4.0825438,-3.473201645,-4.429447784,-6.213461982999999,-4.10272646,-2.910718723,-7.938535213470459,-8.974559783935547,-7.135318279266357,-8.423820495605469,-10.377756118774414 -3461,3461,I206G,0.010808238000000001,-0.034531354,-0.027168147,-0.042055194000000004,-0.507712402,0.024852141,0.020925048999999998,0.000691427,0.050784152,0.027436265,-0.09649897199999999,-0.047684656,-0.0066516380000000005,-0.012505477,-0.07160491,-0.448896081,-0.566528723,1.9931695630000001,2.308482883,-4.415394609,-4.051716248,-4.246923866,-4.0531269839999995,-4.165706337,-5.559499611000001,-3.590996891,-3.2478019689999997,-6.965601444244385,-8.532500267028809,-7.697310447692871,-7.507558822631836,-7.7165207862854 -3462,3462,I206F,0.029917627999999998,-0.068100536,-0.10071218900000001,-0.055906262000000005,-0.115699014,0.093250674,0.08088089400000001,-0.021045638999999998,0.043465694000000006,-0.055184445,-0.08101662700000001,-0.13020727,-0.071217108,-0.075577836,-0.036234687,-0.158680063,-0.07271796400000001,1.363276039,2.126731731,-5.264772165,-4.337665443,-3.2036664889999997,-6.424996765,-6.659254288,-5.69827784,-4.471984568,-2.098540891,-6.31381368637085,-7.325691223144531,-5.677804470062256,-6.552907466888428,-7.3775434494018555 -3463,3463,I206H,0.022876997000000003,-0.073986494,-0.022999822000000003,-0.051760515,-0.490274334,-0.00326561,0.023562108999999998,0.022191885,0.042754319000000006,-0.010723865,-0.137249122,-0.094826348,0.048826704000000005,-0.026899762,-0.076621267,-0.464876178,-0.51567249,1.341771563,1.761573073,-5.219966,-5.158350525,-4.2046432419999995,-5.053256408999999,-5.736261345,-5.947318481,-4.696089267,-3.2569771939999996,-6.747410774230957,-7.710699558258057,-5.753424644470215,-6.261031627655029,-7.930944442749023 -3464,3464,I206K,-0.016521525,-0.052681132,-0.003651442,-0.018567651,-0.166908908,0.102245973,0.062402894,-0.095445944,0.076570818,0.037531549,-0.14289381199999998,0.023802915,-0.031105797999999997,0.03388351,-0.071018812,-0.142929425,-0.19088839100000002,1.339444345,2.232258039,-2.355398444,-3.101410057,-2.386978638,-2.402503037,-1.429256905,-2.456843582,-2.284658349,-0.886288148,-5.746228218078613,-5.1943464279174805,-5.881726264953613,-4.89211368560791,-6.1984710693359375 -3465,3465,I206M,0.04019459,0.033615614,0.042878135,0.018242996,-0.031823082,0.030628627999999998,0.109005315,-0.028616136,0.057253978,0.14793451900000001,-0.080703292,0.036964361,0.048791907999999995,0.115393419,-0.078907427,-0.012413142,-0.051233021,1.253934922,2.705641397,-0.49143781299999995,-0.9194278109999999,-1.0555958859999999,-0.15063781,0.052233101,-0.383760658,-2.060464331,-1.233992727,-4.889947891235352,-5.764651298522949,-5.500685691833496,-4.916103363037109,-5.84389591217041 -3466,3466,I206L,0.041972252,-0.012020969,0.0030750390000000003,-0.027907064,-0.062484205999999994,-0.012539835,0.039540011,0.044404492000000004,0.018396399,0.045216430999999994,-0.069258368,-0.030213991000000003,0.036364068,-0.005862829,-0.049951298,-0.109780622,-0.01518779,1.280598282,2.180638079,-0.036553122,0.55564579,-0.10534706099999999,0.059454047999999995,0.037506355,-0.730024742,-1.988781049,0.8005091129999999,-3.559749126434326,-4.596800804138184,-3.2034993171691895,-4.319582939147949,-4.621625900268555 -3467,3467,I206N,-0.07639246,-0.097453212,-0.084877025,-0.115021107,-0.545276258,-0.032856908,-0.10187433,-0.05091059,0.019878297,-0.097045356,-0.097861067,-0.069200375,-0.10055367400000001,-0.100784376,-0.129257838,-0.583464676,-0.50708784,1.560446251,1.82713522,-4.219549219,-4.542879295,-3.710311043,-2.9704663239999998,-4.730273148,-5.143816284,-3.899577423,-2.183210967,-6.712488174438477,-6.536111831665039,-6.29702615737915,-6.71572208404541,-7.439143657684326 -3468,3468,I206Q,0.029201497000000003,-0.07881144400000001,-0.042334195,-0.025677079,-0.043686221,0.002203199,0.004296914000000001,0.054106079,0.045781937,0.009039369,-0.16666225699999998,-0.074263676,-0.010404714,-0.041794624,-0.009559534,-0.117864662,0.030492221,1.230533656,2.126666669,-1.5226949369999998,-1.917375771,-1.916713539,-0.837482803,-0.663381546,-2.278521027,-2.170622594,-1.412007112,-5.573227405548096,-6.551105499267578,-4.82644510269165,-5.194684982299805,-6.910656929016113 -3469,3469,I206P,0.000471761,-0.291522652,-1.779102921,-2.247104658,-2.7935813310000004,0.050500987000000004,0.018342382,-0.017398861,0.022158294,-0.203388455,-0.379656848,-2.085341555,-1.4728642859999999,-2.312040052,-2.182169264,-2.727773562,-2.859389099,0.6419590039999999,-0.22100654399999997,-7.401030563,-6.512406586,-6.871379822000001,-7.617098854,-7.4493211520000004,-8.554946403999999,-7.193116032000001,-6.609444902000001,-11.172496795654297,-13.196233749389648,-12.094404220581055,-10.607139587402344,-11.81660270690918 -3470,3470,I206S,0.014117386,-0.060086527,-0.029719633999999998,-0.032810553,-0.109283774,0.00025958400000000004,0.012277943000000001,0.015956829,0.039923626000000004,-0.013575131,-0.106597922,-0.063212492,0.0037732240000000004,-0.01245919,-0.053161915,-0.154436056,-0.064131492,1.5168272369999998,2.312321322,-3.7838341489999996,-3.734803543,-3.669640533,-3.487393883,-3.6073060989999997,-4.420026688,-3.245276052,-2.93914146,-6.014639377593994,-6.880531311035156,-6.318889617919922,-5.887048244476318,-6.422334671020508 -3471,3471,I206R,0.025828252000000003,-0.01377985,-0.016197196,-0.038110036,-0.09609221300000001,0.011311628,0.026284887000000003,0.025371617000000003,0.0343773,0.05204758,-0.07960728,-0.068735768,0.036341376,-0.017784993,-0.058435079,-0.140715911,-0.051468515,1.317294567,2.17960245,-1.863715332,-1.2344766390000002,-2.427891823,-1.72367675,-1.0861884990000001,-2.846342949,-1.921414061,0.116348219,-5.488833904266357,-6.089203834533691,-5.704906940460205,-4.8716654777526855,-5.968523979187012 -3472,3472,I206T,0.042614654,-0.022792241,0.0009750410000000001,-0.034564326,-0.092170431,-0.031852644,0.037801507000000005,0.047427801,0.01514372,0.025286599,-0.07087108,-0.020312629,0.022262711,0.001674334,-0.070802985,-0.121416629,-0.062924232,1.319106307,2.243707257,-1.176565407,-1.4465295790000001,-1.51588694,-1.515139503,-0.875823303,-0.529447708,-1.26535325,0.024509321,-4.267072677612305,-5.213869094848633,-4.884765625,-4.2470316886901855,-4.703444480895996 -3473,3473,I206W,0.05810368900000001,-0.053842374000000005,-0.043425503,-0.050314221,-0.059908443,-0.002041336,0.07206676599999999,0.044140612,0.024982288,-0.012563717,-0.09512103,-0.135897928,0.049046922,-0.042665477,-0.057962965,-0.137351878,0.017534992,1.394835485,2.216405331,-5.302861824,-3.8248687360000004,-2.4296989669999998,-5.167549477,-6.690173317,-8.402018623,-5.063644327,-1.201339427,-7.431013584136963,-9.328282356262207,-7.675158500671387,-8.546607971191406,-9.488895416259766 -3474,3474,I206V,0.06953582400000001,0.016368188,0.02299752,-0.024435354,-0.052187525,-0.030983962,0.070100704,0.06897094299999999,0.051695465,0.049900162000000005,-0.017163787,-0.00046566,0.046460699999999994,-0.012251211000000001,-0.036619497,-0.09947531300000001,-0.004899736,1.395511931,2.313337165,-1.3465446330000002,-1.231473282,-1.4253665469999999,-1.65223674,-0.760181358,-1.66346524,-2.454222638,-0.6059509160000001,-3.9291157722473145,-4.195977210998535,-3.945493459701538,-4.28599739074707,-4.204212188720703 -3475,3475,I206Y,0.040908949,0.040893773,-0.079761211,-0.008538211,-0.10040778800000001,-0.109105181,0.046709355999999994,0.035108541,0.09315347800000001,0.13419909800000002,-0.052411552,-0.140506514,-0.019015907,0.031847367,-0.048923789,-0.09142897400000001,-0.109386602,1.3271953429999999,2.2967871140000002,-6.119303307999999,-6.407345352,-3.7153267060000004,-7.455663672999999,-7.152918419,-5.86526239,-5.199908006999999,-1.28047204,-7.039395332336426,-8.267147064208984,-6.413985729217529,-7.3214545249938965,-8.312676429748535 -3476,3476,D207A,-0.062229479000000004,-0.045654257000000004,-0.027258616,-0.031301506,-0.024022197000000002,0.038410698,-0.05996719,-0.064491768,0.032718807999999995,-0.020184848000000002,-0.071123665,-0.042907107,-0.011610125,-0.018439979,-0.044163032000000005,0.011925898999999998,-0.059970292,1.178267571,2.593060595,-0.334295882,-0.001144165,-0.608751328,0.093880608,0.011962357,-1.16742688,-2.439769816,-0.7952136390000001,-5.07153844833374,-4.627697944641113,-5.847004413604736,-4.174415111541748,-4.35892391204834 -3477,3477,D207C,0.010585694,-0.043857762,-0.003090153,0.0056290609999999994,-0.08019127,0.041584525,0.009075379,0.012096009,0.023033137000000002,-0.066821471,-0.020894052,-0.018188746000000002,0.01200844,0.014746,-0.003487878,-0.022340232999999998,-0.138042306,1.184000001,2.533465974,-6.555776992999999,-6.234379272000001,-6.418387077,-7.165271652,-6.430414032000001,-6.53043293,-8.138107932999999,-8.923942928999999,-11.25230598449707,-10.735248565673828,-11.812518119812012,-10.053369522094727,-11.153125762939453 -3478,3478,D207E,-0.04176011,-0.051951305999999996,-0.019379709,-0.033905602,0.004128037,0.027629155,-0.028227375,-0.055292844,0.021005601000000002,-0.019637633999999998,-0.08426497699999999,-0.025794797999999997,-0.012964618999999998,-0.012942098999999999,-0.054869104,0.040631972999999995,-0.0323759,1.128027136,2.776403782,-0.662769107,-0.599143021,-0.88213916,-0.896062767,-0.400706825,-0.5357937620000001,-1.601503474,-0.692290117,-5.056250095367432,-4.974980354309082,-4.955304145812988,-4.559813976287842,-4.3860697746276855 -3479,3479,D207G,-0.038288475,-0.035304962,-0.016086804,-0.027988322000000003,-0.016034947,0.046896712,-0.027638932,-0.048938017,0.00180474,-0.02555868,-0.045051244000000004,-0.004173631,-0.027999977000000002,-0.0017368239999999999,-0.054239819,0.023876772,-0.055946666,1.0604782529999999,2.646715663,-1.376860916,-1.52169265,-1.366205795,-0.47899511,-1.038818863,-2.478592163,-2.905158732,-0.645666795,-5.457493782043457,-4.808757305145264,-4.915247440338135,-4.711716175079346,-4.39780855178833 -3480,3480,D207F,-0.040534289,-0.044215323,-0.048585087,-0.027121364,-0.184123466,0.056235372,-0.004906908,-0.07616167,-0.004511654,-0.041842409,-0.046588237000000005,-0.0510629,-0.046107273,-0.019985381,-0.034257347,-0.148947954,-0.219298977,1.460766913,2.276557478,-6.505832027,-6.155939888,-5.583940941,-7.981839012000001,-6.631290581,-6.176149712000001,-6.7810197489999995,-6.29822789,-10.527731895446777,-11.410943984985352,-11.10759162902832,-9.810981750488281,-10.51999282836914 -3481,3481,D207I,-0.046580737000000004,-0.011509082,0.018161902,-0.024129632,-0.183733321,0.020730646000000002,-0.028920302000000002,-0.064241172,-0.006542496,0.043429902,-0.066448065,0.016490212,0.019833592,-0.0044382679999999996,-0.043820995,-0.086046632,-0.28142000899999997,1.389820332,2.381473061,-4.437585503999999,-4.283929038999999,-4.3803289030000006,-4.637267754,-3.772836502,-5.113565323,-5.193057651,-4.7284600039999996,-10.024614334106445,-10.328776359558105,-9.923620223999023,-8.57713508605957,-9.081862449645996 -3482,3482,D207H,-0.041334043,-0.020158066999999998,-0.025731558999999998,-0.019124019,-0.02671686,0.05108352,-0.016771435,-0.06589665,0.020025283999999997,-0.00252764,-0.037788493,-0.05388908,0.0024259629999999997,0.018489231999999998,-0.05673726900000001,-0.00844768,-0.044986039000000005,1.225252326,2.372969189,-2.0202365909999997,-1.64715464,-2.049554558,-2.3971904680000002,-1.886979317,-2.12030397,-3.156065845,-2.693722337,-6.814332962036133,-7.179193496704102,-7.525120258331299,-6.301532745361328,-5.968449115753174 -3483,3483,D207K,-0.06931475,-0.071966898,-0.033428677999999996,-0.041045916,-0.068487126,0.020119835,-0.048861057,-0.08976844199999999,0.010045264,-0.062542673,-0.081391122,-0.005703034,-0.061154322000000004,-0.004883892,-0.077207939,0.0067783140000000006,-0.143752565,1.160606965,2.538294051,-1.9920116419999998,-1.977584084,-2.241929016,-2.9747031560000003,-1.8723608930000002,-0.893481064,-3.5118291160000004,-1.3013868370000001,-6.492929458618164,-7.173573970794678,-6.814846992492676,-5.962096214294434,-5.555370807647705 -3484,3484,D207M,-0.028001011,-0.021628026,-0.006265159,-0.00327726,-0.025048737,0.017259441,-0.008326609,-0.047675413,0.048785483,0.008112023000000001,-0.051368075,-0.030716035,0.018185717,-0.025834175,0.019279656000000003,0.038750783999999996,-0.08884825800000001,1.207092001,2.7661460110000005,-4.588306856,-4.641037575,-4.223224129,-4.66292543,-4.428940506,-4.985406639,-5.386453962999999,-4.74635679,-10.039202690124512,-9.913972854614258,-9.482964515686035,-9.154767990112305,-9.746103286743164 -3485,3485,D207L,-0.040484176000000004,-0.020028957,-0.0047328990000000005,-0.020144275,-0.064457659,0.037958257,-0.019282428,-0.061685924,-0.020499898,0.000762485,-0.040820398,-0.00531378,-0.004152017,-0.011351501000000002,-0.028937049,-0.031204429,-0.09771088900000001,1.2696555040000002,2.4615261459999997,-3.978099484,-4.030092598,-3.781398926,-4.376586693,-3.561358795,-4.14106041,-4.934837261,-4.268073053,-8.846878051757812,-9.20908260345459,-8.750863075256348,-8.185035705566406,-8.461254119873047 -3486,3486,D207N,0.005602492,-0.011764415,-0.008308064,-0.011479003,-0.010855562,0.07311743799999999,0.027601268999999998,-0.016396286,-0.047756732,-0.041906274,0.018377445,0.0013244079999999998,-0.017940536,0.031479565,-0.054437571,0.000168492,-0.021879615,1.130150153,2.550558713,-1.372388542,-1.050453354,-1.201484451,-2.44535659,-1.146509148,-1.018139168,-4.08296771,-1.6750492369999999,-5.242411136627197,-5.083503723144531,-5.14402961730957,-4.953827857971191,-4.277660369873047 -3487,3487,D207Q,-0.06438732900000001,-0.11555858699999999,-0.051406943,-0.091283528,-0.072254373,0.026744773,-0.057842165999999993,-0.070932492,0.016903379,-0.15554682,-0.07557035299999999,-0.07914947,-0.023664416,-0.113222782,-0.069344274,-0.074834216,-0.069674529,1.4630610640000001,2.441422517,-0.143463402,0.37666898299999996,-0.052730705,-0.14631998400000001,0.218932335,-1.1138676379999999,-2.157923103,-1.2957538370000001,-5.631412029266357,-6.172942638397217,-5.917427062988281,-5.087994575500488,-5.195185661315918 -3488,3488,D207P,-0.077697109,-0.033856525,-0.6797158209999999,-1.926697154,-2.74751331,0.15184383699999998,-0.044482223,-0.110911994,-0.034113887999999995,-0.001209598,-0.066503452,-0.642376265,-0.7170553759999999,-1.87347037,-1.9799239380000002,-2.6606295330000003,-2.8343970869999997,2.019837199,0.915196731,-5.45259476,-5.561102211000001,-5.4828789979999994,-5.603601982000001,-5.2240783539999995,-5.391312256,-6.506493701,-5.374169984,-10.444360733032227,-11.292373657226562,-10.149192810058594,-10.571378707885742,-11.086021423339844 -3489,3489,D207S,-0.011899561000000001,-0.032074722,0.002292015,-0.009120006,0.010865086999999999,0.050958044,-0.001740461,-0.02205866,0.031620201,-0.024541536,-0.039607907000000005,-0.004605499,0.009189529,0.008895522,-0.027135532999999996,0.042116281,-0.020386108,1.040179426,2.597550479,-1.1988190029999999,-0.63722921,-1.348418884,-1.581391525,-1.434955856,-0.992099541,-2.852653432,-1.361043428,-5.426697254180908,-4.769156455993652,-5.5859880447387695,-4.613714694976807,-4.467095375061035 -3490,3490,D207R,-0.045857322,-0.035519088,-0.011863027,-0.017930281,-0.013780093,0.07738064,-0.041279604,-0.05043504,0.014072422,-0.007902791999999999,-0.063135383,-0.015453965,-0.008272088,-0.003612958,-0.032247604,0.013756488999999998,-0.041316675,1.124077095,2.466195628,-0.9784873340000001,-0.5761250920000001,-1.04181707,-1.114392593,-1.177271584,-0.98283033,-1.7796595530000001,-0.893781565,-6.507523536682129,-7.140016078948975,-7.232814788818359,-6.11911153793335,-5.672573089599609 -3491,3491,D207T,-0.07047065400000001,-0.054292584000000005,-0.049724263,-0.030861444,-0.051384057000000004,0.038294737999999995,-0.066665173,-0.07427613400000001,0.0010276439999999999,-0.051911654,-0.056673512999999995,-0.05152922,-0.047919305999999995,-0.02108244,-0.040640447,-0.016912026,-0.085856087,1.235117378,2.449877744,-1.01109523,-1.038826355,-1.191497635,-0.569880882,-0.41311176299999997,-1.842159515,-2.0788784419999997,-1.3758488080000002,-5.730368137359619,-4.595791816711426,-5.8624372482299805,-4.902994155883789,-4.586428642272949 -3492,3492,D207W,-0.06514415,-0.030409455,0.0027828840000000002,-0.007488766,-0.10318134699999999,0.123116941,-0.04721279900000001,-0.0830755,0.001140185,0.027637765,-0.088456675,0.006530866999999999,-0.000965099,0.049810767,-0.06478829900000001,-0.040590798,-0.165771896,1.374225786,2.5683050030000003,-6.25035424,-5.852524047999999,-5.869268798999999,-6.78347905,-6.544884017999999,-6.201615287999999,-7.035980301,-6.0495325079999995,-11.365060806274414,-13.12271499633789,-11.684686660766602,-11.036270141601562,-11.752557754516602 -3493,3493,D207V,-0.085287179,-0.054408889,-0.031817229,-0.042565252000000005,-0.15558870000000002,0.082194495,-0.04350517,-0.127069187,-0.005456108,-0.018672947,-0.09014483,-0.025355229,-0.038279229,-0.013008073,-0.072122431,-0.08039769599999999,-0.230779703,1.354216729,2.413301012,-3.9033064960000003,-3.8364645310000003,-4.161396851,-3.790867516,-3.457358047,-4.270445533999999,-5.067221093,-3.8438382719999997,-8.793536186218262,-8.786616325378418,-8.836593627929688,-7.131735324859619,-8.058349609375 -3494,3494,D207Y,-0.043655291,-0.038464557999999996,-0.050618475,-0.022883952000000003,-0.089946259,0.04955973,-0.042207005,-0.045103576,-0.022475999,-0.004931327,-0.071997788,-0.035946775,-0.065290175,-0.0054962909999999995,-0.040271612000000005,-0.063422925,-0.11646959300000001,1.320972621,2.407009106,-5.04699563,-4.578328491000001,-4.868100067,-6.429979172,-5.04487532,-4.313695098999999,-5.522636609,-4.374461222,-9.816438674926758,-10.651291847229004,-10.254920959472656,-9.377389907836914,-8.937467575073242 -3495,3495,W208A,-0.06362903,0.13914769,0.025023449,-1.467070906,-1.916460922,0.0029734790000000002,-0.027025875,-0.100232185,0.001911014,0.046197388,0.232097992,0.043929489,0.006117408,-1.286832171,-1.6473096409999999,-2.211637873,-1.62128397,0.554059477,0.709617885,-11.14622098,-9.735963073999999,-11.666325,-11.71518243,-10.94425308,-11.66938132,-6.481078749,-2.614055917,-12.624022483825684,-11.792616844177246,-11.382877349853516,-11.90316390991211,-14.78691291809082 -3496,3496,W208C,-0.05714613,0.121219803,-0.029726779,-1.5531601169999998,-2.212615247,0.038373563,-0.011717733000000001,-0.102574526,-0.04853718,-0.0019296510000000001,0.244369257,-0.030530863,-0.028922695,-1.4395623430000002,-1.66675789,-2.389191629,-2.036038864,0.8333378379999999,0.720586869,-12.90465062,-12.87979081,-13.23821391,-13.10976931,-12.76844306,-12.52703603,-8.299972988,-4.964786465,-13.235493659973145,-11.109630584716797,-11.044464111328125,-11.91250228881836,-13.412391662597656 -3497,3497,W208E,-0.062775886,0.09170605400000001,0.006469814,-1.551703331,-2.293189931,-0.002036211,-0.030193206,-0.09535856599999999,0.09710964300000001,-0.027189336,0.210601443,0.009385209,0.003554419,-1.66232332,-1.441083342,-2.1969792580000003,-2.389400604,0.8219953999999999,0.6935463040000001,-13.69049042,-12.98545329,-14.70380125,-13.72492908,-13.78242682,-13.25584165,-9.371033667,-6.297051989,-15.013749122619629,-14.60754108428955,-12.126575469970703,-13.756836891174316,-16.659955978393555 -3498,3498,W208D,-0.051759837999999996,0.066382951,-0.003051528,-0.26760631,-1.7929408080000002,-0.000971192,-0.012447514,-0.091072162,-0.083232493,-0.037924276,0.170690178,-0.025428053,0.019324998,-0.097157113,-0.43805550600000004,-1.89574486,-1.690136755,0.877627705,1.30889981,-12.22653123,-11.05288818,-12.83011995,-12.06188233,-13.23565437,-11.95211134,-7.643585477,-4.2296488519999995,-15.48050308227539,-14.638407707214355,-11.237805366516113,-14.21955680847168,-16.860963821411133 -3499,3499,W208G,-0.063815187,-0.060850883,-1.422979542,-2.0960791469999998,-2.512143778,0.012052073,-0.028916697,-0.09871367699999999,-0.055898817999999996,-0.049935004000000005,-0.071766762,-1.4240738880000001,-1.421885195,-2.0671885740000002,-2.124969719,-2.511667881,-2.512619675,0.807271849,0.059876585999999996,-11.549307,-11.03348699,-12.08071264,-10.49850535,-11.93664297,-12.19718703,-7.471623646,-5.313393607,-13.990259170532227,-11.950311660766602,-11.062728881835938,-12.832256317138672,-14.859427452087402 -3500,3500,W208F,-0.011549843999999998,0.102015059,0.038283691,0.036925221,-0.969442853,-0.020340716000000002,0.028571791000000003,-0.051671479000000006,0.114422618,0.021433433999999998,0.182596683,-0.00268094,0.079248321,-0.030163926,0.104014367,-1.03912241,-0.899763295,0.817433272,1.3680282990000001,-10.20756454,-9.828221663999999,-8.720377441,-10.94900566,-8.882167419,-12.65805051,-7.600700524,-2.814565613,-10.175413131713867,-10.43069076538086,-7.759073257446289,-9.138948440551758,-11.670194625854492 -3501,3501,W208I,-0.082512398,0.119666521,-0.082327535,-1.653077336,-2.5446781990000003,-0.009955122,-0.035991284,-0.129033512,-0.069221779,0.037135375,0.20219766600000003,-0.081402577,-0.083252493,-1.4545215009999999,-1.85163317,-2.330364573,-2.7589918239999998,0.804919196,0.715346478,-10.30938004,-11.89781244,-10.16971111,-12.90300116,-9.402437592,-7.173937912,-7.438310078,-0.550210024,-10.694419860839844,-11.89356803894043,-12.013627052307129,-11.741081237792969,-13.354958534240723 -3502,3502,W208H,-0.036072135,0.12502655199999999,0.018422025,-1.591976934,-2.123041474,0.03256793,0.014804086000000001,-0.086948355,0.14679742699999998,-0.011507168,0.261560271,0.015476496000000001,0.021367554,-1.4430874790000001,-1.7408663880000002,-2.292601613,-1.953481335,0.804984148,0.717418144,-11.1604726,-10.58365697,-13.30779218,-10.09392615,-10.84641489,-10.97057284,-7.683621163,-3.684233724,-13.471203804016113,-12.561790466308594,-11.843307495117188,-12.163896560668945,-15.320646286010742 -3503,3503,W208K,-0.07054185,-0.592445081,-1.7830253059999999,-2.134174362,-2.266433854,0.072954884,-0.038273935,-0.102809765,-0.050996959,-0.6356290689999999,-0.5492610920000001,-1.757851344,-1.8081992669999998,-2.020754787,-2.247593936,-2.794292814,-1.738574894,3.056372756,1.188732294,-13.72657658,-13.06398225,-15.94034407,-13.60854117,-13.5441643,-12.47585112,-9.82486594,-6.560161099999999,-14.05457878112793,-13.887042999267578,-14.330080032348633,-13.576956748962402,-15.639719009399414 -3504,3504,W208M,-0.015287271000000002,0.14924828199999998,0.016696593,0.067860262,-0.953390179,0.030505741,0.026027923999999997,-0.056602465,-0.090411078,0.027860672000000003,0.270635891,0.003099545,0.03029364,0.012474954,0.12324557,-0.831937235,-1.074843123,0.8066982890000001,1.3966525580000002,-9.763819188,-10.08924507,-9.51038797,-11.33913677,-8.955105057,-8.925221069,-6.235516854,-2.450617323,-10.513545036315918,-10.895158767700195,-10.581639289855957,-11.024076461791992,-14.288565635681152 -3505,3505,W208L,-0.052013305,0.149693474,0.037001321000000004,0.07191095900000001,-1.4011797819999998,0.039930587999999996,-0.012083788,-0.091942821,-0.038101977999999995,0.040904146,0.25848280100000004,0.044734685999999996,0.029267955,0.059302137000000005,0.08451978,-1.6274901480000001,-1.174869416,0.59231512,1.310115683,-8.678854317999999,-9.243062851,-8.246988525,-10.67182776,-6.881146164,-8.351246292,-5.768200319,-1.128836958,-9.340669631958008,-10.319992065429688,-7.995499610900879,-9.474142074584961,-12.07374382019043 -3506,3506,W208N,-0.049050576,0.186140764,-0.041764751,-1.6134128319999999,-2.4963600390000003,0.044879293,-0.036276155,-0.06182499599999999,-0.023464288,0.076627632,0.295653895,-0.011726737,-0.071802764,-1.492869815,-1.7339558480000001,-2.5246858569999997,-2.468034221,0.74995331,0.70905245,-12.42419212,-12.44121762,-13.13643768,-11.95745391,-12.86048991,-11.72536151,-8.149273276,-3.58038137,-14.503755569458008,-12.935687065124512,-11.684173583984375,-12.94626522064209,-16.315189361572266 -3507,3507,W208Q,-0.07514014,0.110468458,-0.221968208,-1.689327135,-2.720273122,0.030998695,-0.039981666,-0.110298614,-0.030876787000000003,-0.020839491,0.241776407,-0.108063336,-0.33587308,-1.656697149,-1.721957121,-2.641088541,-2.7994577019999998,0.929496817,0.70740533,-11.71181391,-12.04912492,-13.20082405,-11.92709264,-11.42127155,-9.960756355,-8.352695506,-5.3316344430000004,-13.213140487670898,-12.396435737609863,-11.813984870910645,-12.128149032592773,-15.31637191772461 -3508,3508,W208P,-0.070865373,-1.016465859,-1.906857375,-2.178265016,-3.079917716,0.03426964,-0.040284479,-0.101446266,0.005411839,-1.084570088,-0.9483616290000001,-1.80789324,-2.005821509,-2.154899166,-2.201630866,-2.889413085,-3.270422347,3.1714550389999996,1.075573397,-14.66319947,-13.65804826,-15.47036027,-15.33712205,-13.97173758,-14.87872918,-8.816572792999999,-5.0819716580000005,-15.251213073730469,-15.803104400634766,-14.890188217163086,-15.956071853637695,-17.56659698486328 -3509,3509,W208S,-0.031524286,0.13736700000000002,-0.19024527300000002,-1.6894518219999999,-2.1544361309999998,0.018330803,0.011818549,-0.07486712,-0.17034827600000002,0.003980365,0.27075363399999997,-0.134922921,-0.24556762399999998,-1.618133108,-1.7607705359999999,-2.307026994,-2.0018452680000003,1.053129377,0.722979365,-11.89392921,-11.40514136,-11.87418256,-11.64802093,-12.12481061,-12.41749059,-7.672475359,-4.253343731,-13.117267608642578,-11.121610641479492,-10.285161972045898,-11.694350242614746,-14.492106437683105 -3510,3510,W208R,-0.051789285,-0.286493544,-1.525321092,-2.106920362,-2.8279599689999997,0.047430124000000004,-0.020079081000000002,-0.083499488,0.0008520410000000001,-0.254543917,-0.31844317,-1.5257567269999999,-1.524885456,-2.071778577,-2.142062146,-2.636831816,-3.019088122,2.681788097,1.03146795,-10.84669366,-11.72806085,-12.06998188,-10.35545567,-11.65653661,-8.423433272999999,-8.078607466000001,-5.329241247,-12.446076393127441,-10.97353744506836,-10.497700691223145,-11.273921966552734,-13.433804512023926 -3511,3511,W208T,-0.069405571,0.12638569,-0.18792833399999997,-1.676308318,-2.4204022419999998,0.038934267,-0.025191513999999998,-0.11361962699999999,-0.046444564,0.02742236,0.22534901899999998,-0.11466403300000001,-0.261192634,-1.727916859,-1.6246997769999998,-2.578936347,-2.261868137,0.9406729429999999,0.700051781,-9.868649854,-10.50319552,-10.52746169,-10.08416125,-7.886942795,-10.34148801,-6.895188955,-2.051046061,-12.166364669799805,-12.054375648498535,-11.108382225036621,-11.9952392578125,-14.390058517456055 -3512,3512,W208V,-0.05682759999999999,0.135182222,-0.802637307,-1.800203315,-2.66192783,0.031385009,-0.021477205,-0.092177994,-0.176431749,0.046044297000000005,0.22432014600000003,-0.516499059,-1.0887755540000001,-1.6321148019999998,-1.9682918269999998,-2.824782136,-2.499073524,1.8303746769999998,0.905720545,-11.08542168,-12.06979723,-11.31650025,-12.11756081,-10.29271818,-9.630531952,-5.40677861,-1.793880427,-11.271116256713867,-12.306963920593262,-11.518290519714355,-11.375934600830078,-14.127400398254395 -3513,3513,W208Y,-0.07557349299999999,0.128724001,0.028299705,0.045436385,-1.4290652869999998,-0.021150189,-0.047613332,-0.103533654,-0.127213726,-0.000419124,0.257867125,0.010178378,0.046421032,0.021793292000000002,0.069079478,-1.632434084,-1.22569649,0.547558699,1.3076368090000001,-10.00539543,-10.22075278,-9.609655212,-9.615537514,-9.49898674,-11.08204491,-7.831612207,-3.398521745,-10.55240535736084,-10.814069747924805,-8.474433898925781,-9.571616172790527,-12.645252227783203 -3514,3514,M209A,0.011769685,0.18411577899999998,0.017205486000000002,-1.6199433269999999,-2.03056525,0.035001732,0.020360289,0.003179081,-0.034959897000000004,0.012606257,0.3556253,-0.03689849,0.07130946099999999,-1.264843886,-1.975042767,-2.370179306,-1.690951193,0.947747434,0.750002065,-8.234347057999999,-7.832445961,-8.035463829,-7.929872177000001,-8.600264083999999,-8.77368924,-8.416307439,-6.307476726,-10.655671119689941,-12.540242195129395,-9.306928634643555,-10.217260360717773,-11.523475646972656 -3515,3515,M209C,0.05786613,0.229378553,0.02504521,0.098222533,-1.1524602990000001,-0.072790773,0.071621385,0.044110874,-0.006721416,0.039998431,0.418758674,0.032430105,0.017660315,-0.000171948,0.196617013,-1.634852156,-0.6700684410000001,0.61234398,1.310415243,-10.98406441,-10.75067282,-10.42047305,-10.41566914,-11.08248943,-12.25101762,-10.48843537,-10.30909939,-12.345893859863281,-12.708877563476562,-8.932146072387695,-11.372390747070312,-13.566126823425293 -3516,3516,M209E,-0.032227282,-0.8813101959999999,-2.304691151,-2.319253869,-2.9213960589999997,0.014029284,-0.021535283,-0.042919281,0.030023598,-0.9074268040000001,-0.855193588,-2.7089251360000004,-1.900457166,-2.195325016,-2.443182722,-2.543698485,-3.299093632,0.33925344799999996,-0.620805285,-11.28385336,-10.61390013,-10.94904324,-10.61903944,-11.64503513,-12.59224886,-10.48843537,-10.30909939,-14.639688491821289,-16.048444747924805,-15.335649490356445,-15.784793853759766,-16.385892868041992 -3517,3517,M209D,-0.017045493999999998,-1.564393614,-2.095602608,-2.701630668,-3.002742861,0.012050571999999999,-0.02065937,-0.013431618000000001,-0.089672907,-1.855709602,-1.273077625,-2.172908096,-2.01829712,-2.261367966,-3.141893369,-2.910771431,-3.0947142910000003,-0.597917121,-1.123790675,-11.68870713,-10.959922500000001,-11.60323131,-10.86522088,-12.01450696,-13.00065399,-10.48150989,-10.27089108,-15.167990684509277,-16.631467819213867,-17.24842643737793,-17.51972770690918,-19.317073822021484 -3518,3518,M209G,-0.016201071,0.155156447,-0.14004566400000001,-1.732685089,-2.678930153,0.006776038000000001,0.008220426,-0.040622568,-0.017959241,0.01724087,0.293072023,-0.14290977900000001,-0.137181549,-1.6795113609999999,-1.785858816,-2.596776458,-2.761083847,1.018145967,0.712201933,-10.03010107,-8.954619911,-9.728741966,-9.517863945,-9.818865494,-12.13041405,-8.930507795,-6.952508032000001,-12.948637008666992,-15.377111434936523,-12.1062650680542,-13.670876502990723,-14.698931694030762 -3519,3519,M209F,-0.029783629,0.134616246,-0.14352879300000002,-1.615656226,-2.914586017,-0.015163508999999999,-0.023790582999999997,-0.035776674,0.006690135,0.006832328,0.262400163,-0.151718797,-0.13533878900000001,-1.4612370719999999,-1.77007538,-2.8510032260000004,-2.978168807,1.109838957,0.752625051,-7.451167948999999,-8.403774283999999,-5.547861191,-6.762965027000001,-7.845784042000001,-8.6954552,-7.347199345,-4.154184197,-7.635750770568848,-9.758766174316406,-7.932511329650879,-7.578128337860107,-11.880366325378418 -3520,3520,M209I,-0.053541278,0.127687975,-0.949520824,-1.857301499,-2.834504952,-0.068630775,-0.026762342999999997,-0.080320212,-0.004646334,0.063909442,0.19146650699999998,-0.711026808,-1.188014839,-1.723765964,-1.9908370340000001,-2.7711094380000003,-2.8979004660000003,2.041826766,0.9602672609999999,-6.198722543,-5.259169098,-5.741379936,-6.397368599,-7.178577965,-6.417117118999999,-7.3205966170000005,-4.760548719,-7.841139316558838,-9.11091136932373,-6.933521270751953,-5.917245864868164,-10.757455825805664 -3521,3521,M209H,-0.01826486,-1.286444407,-2.307058752,-2.185120833,-2.8753086519999997,0.05919400599999999,0.0230848,-0.05961452,0.007555643000000001,-1.317929282,-1.254959531,-2.237187767,-2.376929736,-2.325647637,-2.044594029,-3.1511423610000002,-2.599474942,0.053345004,-0.8076681929999999,-11.27219172,-11.05976984,-10.13057114,-10.97843627,-11.24425077,-12.94793058,-9.75981237,-7.503679155,-12.96290111541748,-15.471736907958984,-13.93215560913086,-13.589201927185059,-17.477344512939453 -3522,3522,M209K,-0.059917095,-1.066810284,-2.055304181,-2.24937787,-2.9395656889999997,0.02731059,-0.03285155,-0.08698264,-0.029315557000000003,-0.97892152,-1.154699048,-1.949332527,-2.161275834,-1.912853661,-2.5859020790000002,-2.8632871210000004,-3.0158442560000003,3.491773005,1.412317995,-10.59383957,-10.00724699,-10.39223649,-9.654688599,-10.73265281,-12.18237295,-9.858186806,-7.503679155,-12.348367691040039,-16.2104434967041,-15.664424896240234,-13.651790618896484,-16.365373611450195 -3523,3523,M209L,0.18369905600000003,0.14036505,0.059101975999999994,0.069382862,-0.620492384,-0.049808530999999996,0.06463159,0.302766522,-0.032767502000000004,0.051759862000000004,0.228970237,0.008626495999999999,0.109577455,-0.039284526,0.17805025,-0.73311796,-0.507866807,0.8444287159999999,1.424685583,-3.254801871,-5.433984184,-2.252779243,-2.393698692,-3.59259185,-2.600955383,-4.795122265,0.00491984,-4.595751762390137,-4.698015213012695,-3.1385622024536133,-2.840595245361328,-7.544330596923828 -3524,3524,M209N,0.039360648,-1.031817908,-2.374158591,-2.3921410219999997,-2.781298845,0.06342757,0.058570541,0.020150754,0.04768915,-1.064170155,-0.9994656609999999,-1.983428639,-2.764888543,-2.372918506,-2.4113635369999997,-2.721291975,-2.8413057139999998,0.265210349,-0.665009145,-10.38831378,-9.438246902000001,-10.20355776,-9.379296417,-11.1266406,-11.79382724,-9.301837557999999,-7.062170028,-11.455459594726562,-13.390267372131348,-13.849153518676758,-14.199156761169434,-16.593368530273438 -3525,3525,M209Q,0.353013124,-0.6553106360000001,-0.473593183,-2.121439728,-2.48502129,-0.0014936539999999999,0.050969865,0.655056382,-0.030937244,0.01274323,-1.323364501,-0.32303754100000004,-0.6241488239999999,-2.07188851,-2.170990946,-2.545200716,-2.4248418640000002,1.312499577,0.6705365870000001,-11.31080268,-10.76001436,-10.99082561,-10.67722396,-11.43665037,-12.68929912,-10.48843537,-10.30909939,-11.520489692687988,-13.753368377685547,-12.521031379699707,-12.284847259521484,-14.606804847717285 -3526,3526,M209P,0.000614608,-1.427255247,-2.018035649,-2.450415844,-2.830617872,0.0278144,0.032162208,-0.030932992000000003,-0.096449837,-1.6852222209999999,-1.169288272,-2.073776623,-1.962294675,-2.308364529,-2.5924671580000003,-2.878586748,-2.7826489960000003,-0.060761132999999995,-1.067142865,-11.35745531,-10.74641993,-11.15130801,-10.73334699,-11.68765267,-12.46854893,-10.48843537,-10.30909939,-14.210420608520508,-17.956279754638672,-16.924394607543945,-15.031702041625977,-17.0087890625 -3527,3527,M209S,-0.015921345,0.12963538,-1.4175789980000002,-2.274155201,-2.819777634,0.034742444,0.024844751,-0.056687441,-0.018675398,-0.015144949,0.274415709,-1.347648516,-1.48750948,-2.496806226,-2.051504176,-2.970118432,-2.669436836,0.65588571,0.059889592,-10.85075517,-9.864848755,-10.51553117,-10.365034199999998,-11.12579,-12.38257173,-10.48843537,-10.30909939,-12.156004905700684,-12.663787841796875,-10.872770309448242,-12.017276763916016,-12.820857048034668 -3528,3528,M209R,-0.058272715,-1.390937499,-2.04965505,-2.350668649,-3.260522815,0.02393047,-0.035502469,-0.081042961,-0.11840326300000001,-1.671142238,-1.11073276,-1.9635171480000002,-2.135792952,-2.5290982730000002,-2.172239025,-3.3545929969999997,-3.166452633,-0.229121918,-1.083860858,-11.85905716,-11.16214573,-11.54105358,-11.09559925,-11.95864187,-13.53784536,-10.46529589,-10.13596353,-13.187739372253418,-16.15499496459961,-14.56895923614502,-14.809536933898926,-17.511049270629883 -3529,3529,M209T,-0.007710137,0.17680558300000002,-0.718018598,-2.2440100309999997,-3.405201876,-0.025451562999999996,-0.005623505,-0.009796768,0.009907965,0.000457575,0.353153591,-0.46229411,-0.9737430859999999,-2.283147741,-2.20487232,-3.330491214,-3.4799125369999997,1.351422269,0.575689633,-7.227355137999999,-6.77149353,-6.863253716,-7.110683807000001,-7.655381821000001,-7.735962814,-7.88333753,-5.281195189,-9.37291145324707,-9.746316909790039,-9.722931861877441,-9.303868293762207,-11.553642272949219 -3530,3530,M209W,0.006535758000000001,0.154341123,-0.29280223699999997,-1.8639626930000002,-2.349063279,-0.061086979000000007,0.007188893000000001,0.005882622,-0.01087495,0.05593606,0.25274618600000004,-0.254722626,-0.330881847,-1.732939056,-1.99498633,-2.479252534,-2.2188740240000002,1.2582808840000002,0.732993908,-11.51891489,-11.68998074,-10.77149966,-10.29609209,-11.69972744,-13.13727451,-10.48843537,-10.30909939,-12.083962440490723,-15.107451438903809,-11.450814247131348,-12.93391227722168,-16.46645164489746 -3531,3531,M209V,0.024066897,-0.026424352999999998,-1.53298494,-2.294382739,-2.529281553,-0.037321787,0.045162247,0.002971547,-0.018298257,-0.092757287,0.039908582000000005,-1.65002935,-1.41594053,-2.361738511,-2.227026966,-2.630930734,-2.4276323719999997,0.7921123940000001,0.01177928,-7.980053839,-7.457436241,-7.307254127999999,-7.7540306779999995,-8.78968718,-8.59186097,-8.500501821,-6.359663502,-8.872204780578613,-11.969281196594238,-8.519599914550781,-7.287165641784668,-11.59571647644043 -3532,3532,M209Y,-0.11401198,-0.9518259109999999,-1.9782430969999998,-2.53581615,-2.924973973,0.027968773,-0.112954076,-0.115069884,0.062714725,-1.120606756,-0.7830450659999999,-1.765164184,-2.19132201,-2.455684045,-2.615948254,-2.804057515,-3.045890431,2.43024275,0.40316500299999997,-10.41650902,-10.31264651,-8.941965523,-9.479626305,-10.47513232,-12.87317445,-9.349987951000001,-6.7479335339999995,-11.33267593383789,-13.101097106933594,-12.173254013061523,-11.85451602935791,-15.911935806274414 -3533,3533,E210A,0.405231086,0.388018931,-0.050120514000000005,-0.054879976,-0.372386731,-0.079054029,0.016454322,0.79400785,0.056278537999999996,0.062930556,0.7131073059999999,0.01695591,-0.11719693800000001,0.065281245,-0.175041196,-0.145860111,-0.598913351,1.2393932490000001,2.108541614,-2.669873622,-1.880144669,-2.841089638,-2.159469109,-3.9882665630000003,-2.480398132,-3.302840476,0.07835725,-3.8632652759552,-4.069328308105469,-3.245574712753296,-3.4593286514282227,-3.588696002960205 -3534,3534,E210C,0.043418980999999995,-0.09085302199999999,0.011745722,0.027111991000000002,0.150784067,-0.042845637,0.100126761,-0.0132888,-0.042618706,0.001259993,-0.182966037,-0.03288403,0.056375472999999995,-0.032383407,0.086607389,-0.10738070400000001,0.408948838,1.102568107,2.054550149,-6.143429877999999,-5.881696503,-5.688019089,-5.653897338999999,-7.0942953189999995,-6.399241142,-5.429605626,-2.3626352219999998,-5.485804557800293,-6.954107284545898,-6.24232292175293,-8.077672958374023,-6.6878509521484375 -3535,3535,E210D,-0.010470772,-0.006385618000000001,0.052059100999999997,0.056391822,-0.15808265400000002,-0.058545060999999995,0.029365681,-0.050307224000000005,0.070972484,0.096494939,-0.109266175,0.037748905,0.066369296,0.073681228,0.039102415,-0.339537219,0.023371912,0.8396874520000001,1.57317866,-4.150981783,-3.708028183,-2.9633185419999997,-3.554049492,-5.190730911,-5.338781784,-5.609011627999999,-2.131235656,-5.7652177810668945,-6.534983158111572,-6.279352188110352,-6.862955093383789,-6.073366165161133 -3536,3536,E210G,0.117846663,0.12614804599999999,-0.008503527,0.021204341,-0.326654622,-0.068688007,0.020512616,0.215180709,0.022742514,0.05511795,0.197178141,0.00850118,-0.025508232999999998,0.023253772000000002,0.019154908999999998,-0.5237207110000001,-0.129588533,0.60147228,1.411338368,-5.603778752,-2.739109024,-5.123212776,-6.124613571,-6.702940895,-7.3290174939999995,-5.367433951000001,-0.08863587099999999,-5.489567756652832,-6.1240129470825195,-4.645687103271484,-4.396641254425049,-4.306993007659912 -3537,3537,E210F,-0.049800446,-0.029488683999999998,0.027137356,0.001953757,0.145238067,-0.006087363,-0.005208486,-0.094392406,0.037558342,0.056947309,-0.11592467599999999,0.064445561,-0.01017085,0.015225845,-0.011318331000000001,-0.098144602,0.388620736,1.422248138,2.445432577,-5.9000536939999995,-5.520920746,-4.974382675,-6.004401756,-7.318266014,-5.682297279,-5.045289746,-2.2861467909999997,-4.692986488342285,-7.0145158767700195,-6.143126487731934,-7.216890335083008,-6.047247886657715 -3538,3538,E210I,-0.023842878999999997,-0.072426141,0.038094362,0.069639526,0.34857084299999996,-0.021439062999999998,0.020258062,-0.06794382,-0.009407697,0.112917263,-0.257769545,0.070001847,0.0061868769999999995,0.09172509699999999,0.047553954,0.079605569,0.617536116,1.0787479640000002,3.00070599,-0.512143542,-0.409992271,-0.834536385,-0.620519615,-0.852122719,0.156453278,-2.233015221,-0.13517069199999998,-1.1745901107788086,-3.324679136276245,-2.064215660095215,-3.6750173568725586,-2.6617398262023926 -3539,3539,E210H,0.0044056370000000004,-0.012123861000000001,-0.015931688,0.03566448,0.153639001,-0.068999807,0.038263674,-0.0294524,0.0056398559999999995,0.089031883,-0.113279604,-0.024095777000000002,-0.0077675980000000006,0.046433382999999995,0.024895577000000002,-0.143831665,0.45110966700000005,1.310114585,2.176296874,-5.176834471,-4.262331085,-4.638233284,-6.269197067,-5.714887589,-4.999523331000001,-5.778200837999999,-2.151249966,-3.487091302871704,-4.920234680175781,-5.17950439453125,-5.298472881317139,-3.6914587020874023 -3540,3540,E210K,-0.009865764,-0.070920553,0.011305285,0.03523272,0.232897995,-0.060023106,0.041690078,-0.061421606,0.005435774,0.035212819,-0.17705392399999997,0.0026588809999999997,0.019951688999999998,0.017541138,0.05292430099999999,-0.133046054,0.598842043,1.1839557170000001,2.102080861,-1.779657755,-1.452371071,-1.83388015,-2.5065397259999997,-2.045710793,-1.0597870329999999,-3.811103037,0.7587523209999999,-1.1421561241149902,-1.380875825881958,-1.62623929977417,-2.6256957054138184,-0.5908036231994629 -3541,3541,E210M,-0.028603721000000002,-0.057613261,0.021951169,0.031421455,0.19417498600000002,-0.044399882,0.011077188,-0.06828463,0.009015722,0.055138781,-0.170365303,0.040091269,0.0038110690000000003,0.039579061,0.023263849,-0.053265277,0.44161524799999996,1.171423235,2.36905779,-3.2618946039999996,-3.1042939069999997,-3.50914991,-3.506219002,-4.114300858,-2.075509346,-4.081908536,-1.774940411,-2.3708271980285645,-4.3568525314331055,-2.775362014770508,-4.393431663513184,-4.104640007019043 -3542,3542,E210L,0.002445311,-0.00900026,0.0052436869999999995,0.011845808000000001,-0.15600398699999998,-0.027440425,-0.010908936000000001,0.015799557,0.022582748,0.06093588,-0.07893639999999999,0.006664231999999999,0.0038231420000000003,0.021113596000000002,0.002578019,-0.22660799199999998,-0.085399981,1.4026958969999999,2.0932990019999997,-2.346255745,-2.551316429,-2.470706978,-2.227656799,-3.613330505,-0.868268013,-2.940988705,0.416533108,-1.2980120182037354,-3.7291276454925537,-2.8117191791534424,-3.5726699829101562,-3.603663444519043 -3543,3543,E210N,0.022183999,0.0026827659999999996,0.00019822200000000001,0.055981697999999996,0.082515748,-0.055851987,0.08669166800000001,-0.04232367099999999,0.00129131,0.08254258099999999,-0.07717705,0.01791876,-0.017522317,0.020693168,0.091270227,-0.245414188,0.41044568299999995,1.057480628,1.791401693,-5.130836455,-4.147608322,-5.178827713,-5.0176017989999995,-5.815974838,-5.494169601,-5.103757109,-1.986481164,-3.3473961353302,-4.805675506591797,-4.611732482910156,-4.925161361694336,-3.9124832153320312 -3544,3544,E210Q,0.029467628,0.042838032000000005,-0.010458627,0.079244332,0.054612238,-0.00604481,0.029088588999999998,0.029846667,0.015534909,0.104379383,-0.018703319,0.029768204,-0.050685457,0.086615817,0.07187284599999999,-0.000321649,0.109546125,1.049841855,2.635588792,-1.165588857,-1.1449366909999998,-1.093659943,-1.539025154,-1.110156448,-0.940166046,-2.556013994,-0.7210337,-2.0665829181671143,-2.614335060119629,-2.680361747741699,-2.704802989959717,-1.8093773126602173 -3545,3545,E210P,0.25023387399999997,-0.7178393,-1.8889981059999998,-1.86261881,-1.7423347319999998,0.021406087,-0.045602150999999994,0.5460698979999999,0.098033396,-1.070539519,-0.36513908,-2.471627817,-1.3063683940000002,-2.173774421,-1.5514631980000002,-2.618761029,-0.8659084340000001,0.37096098,-0.668988192,-8.630677802000001,-7.71627108,-8.256324524,-8.49186174,-10.31446027,-8.37447139,-7.979180603,-5.505594114,-8.535396575927734,-9.627021789550781,-8.212084770202637,-8.444109916687012,-8.584644317626953 -3546,3546,E210S,0.025652072999999997,-0.027052057999999997,-0.003643922,0.027287047999999998,-0.42321718700000005,-0.09234781199999999,0.058452923,-0.007148778000000001,0.012297853999999999,0.038846802,-0.092950917,-0.003645981,-0.003641863,0.038008967000000005,0.016565128000000002,-0.57125288,-0.27518149399999997,0.554150851,1.3905700769999998,-4.35257854,-3.62846814,-3.292987877,-3.5753743589999996,-6.025782181,-5.240280144,-3.7459855839999996,0.106292344,-3.7714130878448486,-4.355772495269775,-3.875586748123169,-3.623195171356201,-3.3951988220214844 -3547,3547,E210R,0.068183602,0.013112317,-0.00369791,0.016560909,0.07051385,-0.041405924,0.044509415,0.09185778800000001,0.057476125,0.042053535999999996,-0.015828903000000002,0.003214266,-0.010610085,0.02296335,0.010158468,-0.144723792,0.285751492,1.4134248459999998,2.246096252,-2.5651362559999997,-2.204315186,-2.234721687,-2.8774660489999997,-3.500263908,-2.008914452,-3.150688365,0.674518058,-2.1013801097869873,-2.7363550662994385,-2.795050859451294,-2.8626294136047363,-1.6531926393508911 -3548,3548,E210T,0.04238607900000001,-0.00265192,-0.046493902000000004,0.016081757,-0.342551855,-0.06225205599999999,0.050355392,0.034416765,0.028799909,0.054291674000000005,-0.059595514,-0.026601157,-0.06638664700000001,-0.005856914,0.038020427,-0.290734877,-0.394368833,0.833966965,1.606469575,-2.8684812269999997,-2.137548599,-2.085857933,-2.598519135,-4.066275429,-3.45420504,-3.704598044,-0.106336189,-2.291933536529541,-3.4001193046569824,-2.407230854034424,-3.1446051597595215,-2.7795209884643555 -3549,3549,E210W,0.012151111000000001,-0.050290363,0.001876334,0.008089816,0.10454532,0.007023058,0.033860823,-0.009558601,0.02065182,0.016412327,-0.11699305199999999,-0.002385247,0.006137914,-0.014711868999999999,0.030891500000000002,-0.119579835,0.328670474,1.183900381,2.056735716,-8.402763822999999,-7.40000161,-8.425591705,-8.747386467,-10.12834035,-7.312498978,-6.9656375729999995,-4.397539683,-6.476720809936523,-8.198603630065918,-7.815959930419922,-9.095287322998047,-7.121837615966797 -3550,3550,E210V,0.094897041,0.09651764199999999,-0.011035055,0.027370832,-0.1782236,-0.051246006,-0.000451825,0.190245907,0.034669544,0.056379266,0.13665601800000002,0.000634062,-0.022704172,0.023163938,0.031577726,0.005762714,-0.36220991399999997,1.150298002,2.5692927709999998,-0.290004659,-0.232349403,-1.070384277,0.098878334,-0.69243856,0.446270615,-2.018290134,0.11553045,-1.4385528564453125,-3.1405091285705566,-1.9948670864105225,-3.3683624267578125,-2.242487907409668 -3551,3551,E210Y,-0.000453559,-0.065894385,0.04450931599999999,0.031305032,0.35579066299999995,0.026906001000000002,0.08020906,-0.081116178,0.11135296800000001,0.06331163599999999,-0.195100405,0.058407605999999994,0.030611025,-0.009979298000000001,0.072589362,0.005709788,0.705871537,1.206364278,2.599664057,-6.292568446000001,-4.966194641,-5.797284477000001,-6.646789093,-8.34468145,-5.707892571,-5.604529161,-2.452820746,-5.0457763671875,-6.439509391784668,-6.570390701293945,-7.30763053894043,-5.606109619140625 -3552,3552,A211C,0.165597556,-0.330561522,0.065873025,-0.020063676000000003,-0.286941361,-0.090317373,-0.051380898,0.382576009,-0.034893658,0.009849609,-0.670972653,0.064905899,0.06684015,-0.015475902,-0.02465145,0.018601742,-0.592484464,1.27048636,2.589348045,-7.11529586,-7.338139877000001,-8.034015656000001,-6.991797073,-7.235534256,-5.976992439,-6.3886150289999994,-4.753808458,-8.387008666992188,-8.625199317932129,-9.978442192077637,-8.214290618896484,-7.722545146942139 -3553,3553,A211E,0.040779795,-1.2e-05,0.073465257,0.076926871,-0.0032463659999999997,0.021890841,-0.021297886000000002,0.102857475,-0.0018870129999999999,0.07817866,-0.078202738,0.13944372300000002,0.00748679,0.033456118,0.12039762300000001,0.098256785,-0.104749516,1.04450295,2.768537148,-1.9195632230000002,-1.505683266,-2.565458199,-2.347578384,-1.288588577,-1.89050769,-2.335297227,-0.727801826,-5.53392219543457,-7.000468730926514,-6.034065246582031,-6.094203472137451,-5.8957719802856445 -3554,3554,A211D,-0.052752260999999995,0.075491213,0.118134646,0.085846757,0.149351808,0.039283617,-0.042487185,-0.063017337,-0.003985289,0.077046036,0.07393639,0.145437985,0.090831306,0.132574413,0.039119101,0.054618954000000004,0.24408466199999998,0.963688861,2.732984773,-1.243541087,-0.643802406,-1.7563286359999999,-1.28115126,-1.342334023,-1.194089111,-2.315357272,-0.683619103,-5.196313381195068,-5.5689263343811035,-6.2421722412109375,-5.597477436065674,-5.9400177001953125 -3555,3555,A211G,-0.012761912,0.07680614599999999,0.054519424000000004,0.052699065,0.047543237,0.001702951,-0.037532417,0.012008594,-0.046374032,0.072329323,0.081282968,0.070716058,0.03832279,0.042426329000000006,0.06297180000000001,0.04937324,0.045713233,1.055561019,2.6023994790000002,-2.150582678,-1.970054405,-2.5171848530000003,-1.162150978,-3.37373645,-1.729786705,-2.304643025,-0.134907993,-2.963804244995117,-3.7639636993408203,-4.3658223152160645,-3.377340078353882,-2.9025588035583496 -3556,3556,A211F,-0.088204586,0.016797164,0.019205139,0.013035036000000002,-0.547828864,-0.07307683599999999,-0.182317477,0.005908305,-0.049134097,0.006574018,0.02702031,0.109998666,-0.071588389,0.11859591300000001,-0.092525842,-0.30303965899999996,-0.792618068,0.777656075,1.582281234,-8.376490187,-10.01766257,-8.919344849,-7.219008667000001,-7.61880751,-8.107627342,-6.234884762999999,-4.033410673000001,-8.042607307434082,-9.77365493774414,-8.979547500610352,-8.448741912841797,-9.260732650756836 -3557,3557,A211I,-0.001845151,0.19721603199999999,0.052569600999999994,0.033817436,-0.664675484,0.013229461000000001,-0.030018545,0.026328242999999998,-0.0063951730000000005,0.004890238,0.389541825,0.044487994,0.060651208,0.021221662000000002,0.04641321,-0.774315678,-0.55503529,0.591209788,1.364152618,-5.818475171,-5.902504601,-6.63425042,-4.723353653,-6.4080243679999995,-5.424242812999999,-5.427792033999999,-4.3564703510000005,-7.645898818969727,-9.139932632446289,-8.737079620361328,-7.518704891204834,-8.696112632751465 -3558,3558,A211H,0.002109154,0.127979186,0.060033759000000006,0.07203824,0.10639186099999999,0.026572092000000002,-0.07414577,0.078364077,-0.05351316,0.10232096,0.153637411,0.102401485,0.017666033,0.074423284,0.069653195,0.053387639,0.159396083,0.954870595,2.808905419,-4.43532399,-3.9612735669999997,-4.803433846,-4.162707008,-5.694847221,-3.5543583069999998,-2.920817997,-1.568895044,-5.281074523925781,-5.129358291625977,-7.096903324127197,-4.9705047607421875,-5.606398105621338 -3559,3559,A211K,-0.016473945,0.04691903,0.004852124,0.1012606,0.00473626,-0.16906208399999997,-0.113662776,0.080714886,-0.092599791,0.30719869899999996,-0.213360639,0.136327605,-0.126623357,0.161315268,0.041205932,0.088229028,-0.078756508,1.106945548,2.948048726,-4.749191087,-5.8721646960000005,-4.997145584,-5.83884774,-5.190861092,-1.846936325,-5.2269561,-1.26059231,-4.648628234863281,-4.684925556182861,-6.024904251098633,-5.210982799530029,-5.015446662902832 -3560,3560,A211M,0.141218393,0.119000724,0.187974355,0.211863595,0.299713579,0.00877512,0.09013838,0.192298405,0.11677933199999999,0.18587041699999998,0.052131030999999994,0.226739562,0.149209147,0.144181833,0.279545356,0.11166199999999998,0.487765158,0.86488049,2.984459774,-4.074415623,-4.497206955,-4.343359215,-3.843191231,-4.080276993,-3.608043724,-3.790586577,-3.4065451,-7.068716526031494,-8.930805206298828,-7.968696117401123,-7.58992862701416,-8.523375511169434 -3561,3561,A211L,-0.00962619,0.07696012599999999,0.056369750999999996,0.009543409000000001,0.08435156,0.008232106999999999,-0.057288505999999996,0.038036127,-0.059179544,0.020111988,0.133808263,0.075556707,0.037182794,-0.010385142,0.029471959,0.0018480870000000002,0.166855032,1.082920395,2.6377671869999997,-5.402906206,-6.025229111,-5.543777405,-4.858358162,-6.31787484,-4.269291512,-5.492110319,-1.865964711,-6.169188499450684,-8.136374473571777,-7.02053689956665,-6.543724536895752,-7.859736442565918 -3562,3562,A211N,-0.081826003,-0.049166152000000005,0.045194104000000006,-0.025987878,0.007469645,-0.059988837999999996,-0.120313377,-0.043338629000000004,0.129151681,-0.06764780299999999,-0.030684500000000003,0.070755072,0.019633136000000002,-0.10438676599999999,0.05241101,-0.076015365,0.09095465400000001,1.344865886,2.240470862,-2.144776646,-2.626895439,-2.747247345,-1.8574449080000002,-2.315781029,-1.176514511,-2.370767461,-0.8012992059999999,-3.8911194801330566,-3.148047685623169,-5.815356731414795,-4.577945709228516,-4.916324615478516 -3563,3563,A211Q,-0.131027262,0.08314495400000001,-0.037549245,-0.0019919829999999997,0.085666892,0.011033528999999999,-0.19013506300000002,-0.07191946,-0.027119261000000002,0.072593818,0.09369608900000001,0.043757473,-0.118855962,0.048014839000000004,-0.051998804,0.06554199299999999,0.10579179,1.2485966640000001,2.964181393,-3.578374222,-3.71016494,-4.322492805,-3.7272695010000003,-3.931403519,-2.200540344,-3.971425196,-1.17057196,-4.7179388999938965,-5.256572723388672,-4.467188835144043,-4.8781962394714355,-5.227470874786377 -3564,3564,A211P,0.07737986599999999,-0.17221531899999998,0.043309608,-1.143943523,-1.6214594709999999,-0.074692645,-0.027627477999999997,0.18238721,-0.043907176,0.038788508,-0.383219146,0.040794409,0.045824807,-0.995269783,-1.292617263,-1.69100268,-1.551916261,2.797967356,2.121657129,-6.497865517999999,-5.8093539729999994,-6.544515381,-6.1851129,-8.009903549,-5.940441787999999,-5.664476175,-5.075258983,-9.071730613708496,-10.765202522277832,-9.709035873413086,-8.21528434753418,-10.60323715209961 -3565,3565,A211S,0.080007247,-0.098643823,0.054251319000000006,0.017855886,-0.057107732,0.009393837,-0.004738223,0.164752717,-0.03949482,0.001128053,-0.19841569899999997,0.010390116,0.098112522,-0.044411074,0.080122846,-0.019927625,-0.09428783800000001,1.27419062,2.5090696869999998,-2.9993519710000003,-3.468783981,-3.1158116380000003,-2.505376686,-4.054406525,-1.8523810269999998,-3.646082357,-1.7870187819999999,-3.7601218223571777,-4.604559421539307,-5.162036895751953,-4.4223127365112305,-5.046008110046387 -3566,3566,A211R,0.021456189,0.00490232,0.050610907000000004,0.066860696,0.028937467,0.031171065,-0.051059065,0.093971443,-0.023898274,0.072513825,-0.062709186,0.08638229,0.014839523,0.059096865,0.074624527,0.07122327,-0.013348336,1.168924577,2.9542246010000004,-4.138032835,-4.393217674,-5.5323741989999995,-3.853051537,-5.59099025,-1.320530518,-2.8771605460000003,0.026331551,-3.9563140869140625,-2.978634834289551,-5.8559370040893555,-3.0443201065063477,-3.4679298400878906 -3567,3567,A211T,-0.02376757,0.09466592199999999,0.03166356,0.026301236000000002,-0.316316504,-0.032809175,-0.052790684000000004,0.005255544,-0.033685606,0.108324398,0.081007446,0.04661335,0.01671377,-0.0030917970000000003,0.055694268,-0.270891007,-0.36174200100000004,1.04127448,1.748284181,-3.439151752,-3.894630836,-3.415350777,-2.771771118,-4.492446243,-2.621559784,-3.675758358,-1.821075286,-4.548027992248535,-6.238140106201172,-5.690347194671631,-5.136934280395508,-5.866091728210449 -3568,3568,A211W,0.050143737,-0.162096842,0.053618861,-0.013974251000000002,-0.8102898940000001,0.038888442,-0.118045516,0.21833298899999998,-0.015609413999999999,0.069370451,-0.393564134,0.07052979599999999,0.036707925,0.022107977999999997,-0.050056479,-0.384344599,-1.236235188,0.9133672979999999,1.577427361,-8.729997198,-9.066754257000001,-10.50896852,-8.368019936,-8.706284088,-6.99995919,-6.259128764,-4.675589372,-9.414850234985352,-11.302717208862305,-10.767827987670898,-9.564634323120117,-10.737959861755371 -3569,3569,A211V,-0.000675747,0.105957516,0.046432544000000006,0.080167616,-0.649735281,-0.010412309,-0.032570517,0.031219023,-0.071782057,0.117682649,0.094232383,0.123897276,-0.031032188,0.08503850800000001,0.07529672400000001,-0.699217822,-0.600252739,0.350906775,1.341018564,-5.881790659,-5.886832954,-6.439836929,-5.573355583,-5.858073151,-5.650854675,-5.953061484,-4.6076950519999995,-7.0856804847717285,-7.971632480621338,-7.158906936645508,-6.6770219802856445,-7.625467300415039 -3570,3570,A211Y,0.054087475999999995,-0.010895512,0.157771256,0.077594306,-0.353034012,-0.045219398,-0.074972939,0.18314789,-0.047128115,0.177455406,-0.19924643,0.16887243,0.146670081,0.032358028,0.122830584,-0.031396804,-0.67467122,1.321109761,2.547728722,-8.209191608,-9.055009644,-8.795346016,-7.325202705,-7.666591437999999,-8.203808235,-6.169640514,-3.9043921839999998,-7.791996002197266,-8.37483024597168,-8.705083847045898,-7.898284912109375,-8.436092376708984 -3571,3571,D212A,0.067048026,-0.007268238000000001,0.085416434,-0.048719385999999996,-1.4509381430000001,-0.060816565999999996,0.073489956,0.060606096,0.034881477,0.041216548,-0.055753023,0.0018027070000000002,0.16903016,-0.137268515,0.039829744,-1.6428547619999998,-1.259021523,0.7982884370000001,1.320195467,-9.137807828,-8.047322449,-7.5218458560000006,-11.19227575,-8.969851509,-9.957743576,-5.657073737,-0.268618658,-5.25018310546875,-9.374610900878906,-7.006803035736084,-5.62653923034668,-8.836321830749512 -3572,3572,D212C,0.042196129000000006,0.118190169,0.06767303200000001,-0.6951301940000001,-2.102952115,-0.147179841,0.020206272,0.064185986,-0.023335482,0.078705861,0.157674476,0.061585163,0.07376090099999999,-0.48452210799999995,-0.905738279,-2.338430451,-1.867473779,1.506708722,1.282049832,-9.883662787999999,-9.760578873,-9.705652748,-11.28704755,-9.791674644,-8.873360123,-4.954221243,1.147943095,-2.5670485496520996,-7.039989948272705,-5.186228275299072,-6.6746063232421875,-6.038002014160156 -3573,3573,D212E,0.02848791,0.106854125,0.06504088200000001,-1.12509824,-1.56686785,-0.147937816,0.059278553,-0.002302733,-0.017086531999999998,-0.0033512159999999997,0.217059466,-0.022958282000000003,0.15304004599999999,-1.177929252,-1.072267227,-1.8065283140000001,-1.327207385,2.267425571,1.596148081,-8.270353557,-8.041598907000001,-8.206011154,-6.930916565,-8.796123611,-9.377117546000001,-7.448054367999999,-2.675542949,-4.732336521148682,-8.161425590515137,-6.489275932312012,-4.836922645568848,-8.939105033874512 -3574,3574,D212G,-0.029872316,0.050154026,0.097812251,0.172463174,-1.068630148,-0.065869918,0.040584287000000004,-0.100328919,0.040260254,0.059426037,0.040882014,0.003400339,0.192224163,0.03895267,0.305973677,-1.137002783,-1.0002575120000001,0.628253195,1.336712476,-6.312953584,-5.602363861000001,-6.317978424,-6.742556625,-6.794542015,-6.107326996,-4.812017345,-0.286854059,-4.138704776763916,-6.903395175933838,-5.204301834106445,-5.291935920715332,-7.544910907745361 -3575,3575,D212F,-0.04949869,-0.280926648,-0.104026414,-1.580677415,-1.875844696,0.148430416,-0.147842267,0.048844887999999996,-0.020506192,-0.043323744000000004,-0.518529551,-0.168936328,-0.039116500000000005,-1.8956824859999999,-1.265672344,-2.193288329,-1.558401063,1.065252403,0.6873702759999999,-16.61079407,-17.04480203,-17.14919669,-15.07832938,-17.44860095,-16.3330413,-9.887251498,-6.66660981,-7.123777866363525,-13.807830810546875,-8.77368450164795,-8.077527046203613,-12.996139526367188 -3576,3576,D212I,0.031287058,-0.232358867,-0.17885083,-1.42118526,-1.5658375430000002,0.18187058399999997,0.028829212000000003,0.033744903,0.078373414,0.020063235,-0.484780968,-0.343093087,-0.014608573,-1.485508021,-1.3568624980000001,-1.7831138640000002,-1.348561221,3.57419437,2.593422806,-13.77856117,-12.79292319,-12.60661906,-15.044749599999998,-15.120381900000002,-13.32813211,-6.87835414,-0.660732642,-5.719021797180176,-11.694181442260742,-10.327134132385254,-8.971122741699219,-10.318063735961914 -3577,3577,D212H,0.062273657999999996,0.026584936,0.043736705,-1.340260784,-1.6831580380000002,-0.11879501599999999,0.048369047000000005,0.076178268,0.038575952999999996,0.006374426999999999,0.046795445,-0.007005447,0.094478856,-1.2648137990000001,-1.415707769,-2.02105749,-1.345258585,2.511301559,1.6892451080000002,-11.02462231,-11.4639108,-12.11021054,-9.97693502,-10.46261859,-11.109436599999999,-7.164422184,-2.41375865,-4.058192253112793,-8.491594314575195,-6.234353065490723,-3.6560816764831543,-9.722464561462402 -3578,3578,D212K,0.01543215,0.060548834,0.017496813,-0.287656941,-1.616297616,-0.259782478,-0.085665975,0.116530274,0.073574531,-0.009545318,0.130642985,-0.22058809699999998,0.255581722,-0.48169281799999997,-0.093621063,-1.925426696,-1.307168536,1.754047212,1.416026293,-13.06921737,-12.46810815,-15.33546486,-13.26565019,-12.46157943,-11.81528421,-7.40848703,-2.7014090019999997,-6.470979690551758,-12.22891902923584,-9.448413848876953,-6.930051803588867,-10.429488182067871 -3579,3579,D212M,0.137263212,-0.08621225099999999,0.038204155,-1.4615968559999999,-1.668718507,-0.009163435,0.09919920800000001,0.175327215,-0.053298705,-0.214931398,0.042506895999999995,-0.195329289,0.271737599,-1.51958781,-1.403605901,-2.118223649,-1.219213365,2.728808771,1.71184133,-14.82975552,-13.31465385,-14.11977993,-16.10816054,-15.73338357,-14.87279971,-8.098658947,-3.30049966,-6.115251541137695,-13.0050048828125,-9.37456226348877,-8.792972564697266,-12.757091522216797 -3580,3580,D212L,0.046244272999999995,0.008860326,-0.145093688,-1.705730253,-2.467021641,0.07879159,0.044853788,0.047634758,-0.062271453,0.015396143999999999,0.002324508,-0.278919765,-0.01126761,-1.8755259919999998,-1.5359345130000002,-2.54110862,-2.392934662,1.290198693,0.7126342290000001,-15.45833308,-14.98532079,-15.20282879,-16.27529118,-16.58074883,-14.24747579,-7.626242221,-2.79669284,-5.723398208618164,-12.935769081115723,-9.046506881713867,-9.186687469482422,-13.012983322143555 -3581,3581,D212N,0.035139747,-0.039206784,0.17803315600000003,0.242119395,-0.990291815,-0.117875655,-0.077573298,0.14785279199999998,0.007094474,0.17416020000000001,-0.252573767,0.104064944,0.252001368,0.143731633,0.340507157,-1.114107083,-0.866476547,0.735274658,1.351840776,-3.3921070560000004,-3.5995731280000003,-3.415153984,-2.7888054660000003,-2.992302925,-4.164699776,-3.371026388,2.712400166,-0.28613853454589844,-2.981231689453125,-1.2358989715576172,-0.03358793258666992,-1.7256155014038086 -3582,3582,D212Q,0.425552231,-0.344646103,0.041474325,0.167395392,-1.0833758279999999,0.024292058,0.056585736,0.794518726,0.134489356,0.032849679,-0.722141884,-0.024978517000000002,0.10792716599999999,0.071681701,0.263109083,-0.8818595140000001,-1.284892141,0.5942557279999999,1.353271186,-11.04012304,-11.500037800000001,-12.88237779,-9.906479477000001,-12.89137988,-8.020340279,-6.016136191,2.432267668,0.757227897644043,-9.510187149047852,-7.322327136993408,-5.4239091873168945,-10.477197647094727 -3583,3583,D212P,0.114636793,-0.098859339,0.056577642000000004,0.017671171,-1.765575956,-0.183885842,0.042944517,0.18632906899999999,0.073838314,0.0228327,-0.220551377,-0.03054781,0.143703093,-0.068259573,0.103601914,-1.747850278,-1.783301634,0.598780281,1.305529474,-13.52414235,-13.00648797,-13.50836068,-14.06186008,-13.66988313,-13.37411991,-6.5205254,-1.521214627,-5.715884685516357,-11.49659538269043,-7.101972579956055,-7.272025108337402,-10.999330520629883 -3584,3584,D212S,0.114062866,-0.070586778,0.088390618,0.14898735,-1.350442793,-0.145487229,0.06719185700000001,0.160933875,0.044913540999999994,0.067981996,-0.209155552,-0.013048455,0.18982969100000002,0.015894369,0.282080331,-1.424875031,-1.276010554,0.6095640210000001,1.3189698109999999,-7.369889467999999,-7.559662476000001,-6.881417404,-8.116803871,-5.955345497000001,-8.336218094,-4.661864568,1.196876562,-3.3463354110717773,-5.6451568603515625,-3.704833984375,-3.852731227874756,-5.307599067687988 -3585,3585,D212R,0.16278377300000002,0.011739728,0.10097593199999999,-0.625320886,-2.395898308,-0.06380517299999999,0.067106779,0.258460766,0.059195639,0.020664386,0.00281507,0.020443164,0.18150870000000002,-0.57446387,-0.676177901,-2.219024203,-2.572772412,1.692525312,1.336529886,-13.46444152,-14.46093436,-14.51072019,-14.31182519,-12.80359941,-11.23512846,-7.789945976,-2.719851725,-5.773762226104736,-12.505456924438477,-8.533285140991211,-6.731634616851807,-11.405315399169922 -3586,3586,D212T,0.236492311,-0.346922513,0.08565086699999999,0.13004678,-1.4328847669999998,-0.085642828,0.010008491,0.46297613,0.10393874800000001,-0.018308037,-0.675536989,-0.003544914,0.174846647,0.027634907,0.23245865300000002,-1.405633537,-1.460135996,0.955470413,1.348777149,-9.206155347000001,-7.8109485020000005,-8.46278669,-11.06114219,-10.46770844,-8.228190918,-6.00124858,2.0399797769999997,-3.7608084678649902,-7.959179401397705,-6.245047569274902,-4.830492973327637,-6.312850475311279 -3587,3587,D212W,0.146557348,0.231281376,-0.093678712,-1.374198275,-1.9703955519999998,0.054259111,0.15108901800000002,0.14202567800000002,0.050241887,0.17644296199999998,0.28611978899999996,-0.20844486899999998,0.021087446,-1.634161032,-1.1142355179999999,-2.23279687,-1.7079942330000002,1.327769763,0.759061755,-15.83491338,-15.70733674,-16.17983297,-15.55259409,-16.483864699999998,-15.25093839,-9.887251498,-6.66660981,-8.318565368652344,-15.460951805114746,-10.012358665466309,-10.25010871887207,-13.695161819458008 -3588,3588,D212V,0.009144911,-0.076412805,0.036872162,-0.43643010200000004,-1.8490246830000001,-0.038434612,-0.009314019,0.02760384,0.050241887,0.005326944,-0.158152554,-0.05654399,0.13028831400000002,-0.45423142899999996,-0.418628775,-1.801055294,-1.896994071,1.702697449,1.4374540690000002,-13.10027038,-11.85069236,-12.40362946,-14.75538599,-13.65257039,-12.83907369,-6.2536905670000005,-0.074646801,-4.715469837188721,-10.766072273254395,-8.901097297668457,-7.754153251647949,-10.036763191223145 -3589,3589,D212Y,0.050627088,-0.208969286,-0.091051113,-1.770972205,-1.9780938559999999,-0.022259684,0.020775838999999997,0.080478337,-0.056091605,-0.088230511,-0.32970806,-0.147747029,-0.034355197000000004,-1.4237008709999999,-2.118243538,-2.323366705,-1.632821006,1.357390435,0.80884922,-14.87110054,-14.12619893,-16.9445811,-13.23498289,-15.62986945,-14.41987035,-8.999293042,-4.316477437,-6.4094390869140625,-10.823530197143555,-7.864752769470215,-5.6829657554626465,-10.544568061828613 -3590,3590,K213A,0.013259035,-0.178596377,-0.033302257,-0.09921299300000001,-0.15013473,0.010471139,-0.032336336,0.058854406,0.0034436490000000004,-0.069134057,-0.288058697,-0.110557455,0.043952940999999995,-0.185825858,-0.012600128,-0.085898772,-0.214370688,1.355691652,2.262272709,-5.529450345,-5.83233596,-5.244788048,-5.320082886000001,-5.891895622000001,-5.358149208,-3.5839231760000003,-0.946880266,-6.629372596740723,-8.045235633850098,-5.196965217590332,-7.6524434089660645,-6.015755653381348 -3591,3591,K213C,0.030701275,-0.155489534,-0.014017948,-0.063654057,-0.407447461,-0.016037957,0.009640707,0.051761842999999995,-0.059139620999999996,-0.116993838,-0.19398523,-0.085254808,0.057218912999999996,-0.152884698,0.025576584,-0.29342034899999997,-0.521474572,1.7298564630000002,2.197669006,-9.205811482,-9.05472847,-8.584701477000001,-9.826750191,-9.748060172999999,-8.814817101000001,-7.7361212120000005,-5.450530175,-10.12453842163086,-11.303256034851074,-10.95751953125,-11.666908264160156,-9.367079734802246 -3592,3592,K213E,0.007355197,-0.141519327,-0.036711249,-0.102793969,-0.9269661109999999,-0.027090994,-0.024548187000000003,0.03925858,0.092541735,-0.072850159,-0.21018849399999998,-0.116757481,0.04333498400000001,-0.139621356,-0.065966582,-0.7440457140000001,-1.1098865070000001,1.5971406330000002,1.7444851330000002,-4.764894188,-5.450195244,-4.8130348210000005,-4.5944560999999995,-3.814447098,-5.152337677,-3.6569701880000003,-0.757827198,-6.265606880187988,-6.79363489151001,-5.691932678222656,-7.5781569480896,-6.140208721160889 -3593,3593,K213D,-0.01676274,-0.106221292,-0.32591976100000003,-1.631917997,-1.568932922,-0.092840669,-0.01461266,-0.01891282,0.078199049,0.024545882999999998,-0.236988466,-0.253576779,-0.398262743,-1.487169811,-1.7766661830000001,-1.6965020030000002,-1.441363841,3.737037393,2.792058975,-7.606757166,-7.939579437000001,-7.386201324,-7.570781333999999,-7.667330933,-7.469892799,-6.045118872000001,-2.20709935,-7.364137649536133,-9.346585273742676,-7.207716941833496,-9.495442390441895,-7.984210968017578 -3594,3594,K213G,-0.011407198,-0.106674859,-0.015774903,-0.071999245,-0.72143042,-0.014105814,-0.049016885999999996,0.02620249,-0.061659332000000004,-0.040447127,-0.17290259100000002,-0.073490296,0.041940491,-0.126312846,-0.017685644,-0.604697935,-0.838162905,1.5832389059999998,1.7981661830000002,-6.764265207999999,-7.520170097,-6.5204290160000005,-7.200283257000001,-7.120248322,-5.460195351,-4.537027693,-2.468453078,-7.615777969360352,-10.663980484008789,-6.6479291915893555,-8.651246070861816,-7.057318210601807 -3595,3595,K213F,-0.031636376,0.052864968,0.029665947,-0.006411961,-0.338193495,0.016994781,-0.056583441,-0.006689311,0.003190878,0.08891852300000001,0.016811413,-0.04235224,0.10168413400000001,-0.048531933,0.035708012000000004,-0.320750943,-0.35563604600000004,1.4439980590000001,1.9722202640000002,-9.910245035,-9.116238312,-9.718779839,-10.08842078,-9.614059418,-11.01372682,-7.162237796,-3.196131357,-10.176273345947266,-11.370184898376465,-9.578783988952637,-11.377665519714355,-9.294923782348633 -3596,3596,K213I,-0.055547307000000004,-0.1818019,0.006204691,-0.11166310900000001,-0.18181197899999998,0.125034358,-0.120336027,0.009241413,0.017201591999999998,0.004909915,-0.368513715,-0.046372305999999995,0.058781687,-0.17351000600000002,-0.049816211,-0.142917385,-0.220706572,1.404441966,2.15873831,-6.835935056,-7.2536301420000004,-6.580871498,-7.843138924,-6.084800247,-6.417234467,-5.114658545,-2.097765929,-7.1700053215026855,-8.664978981018066,-8.252763748168945,-9.22764778137207,-7.532407760620117 -3597,3597,K213H,-0.017596653,-0.143980558,0.00662126,-0.09725712199999999,-0.24709088399999998,0.016182171999999998,-0.051418142,0.016224836,-0.016676793999999998,-0.061928829000000005,-0.22603228600000003,-0.079076865,0.092319384,-0.148360775,-0.046153467999999996,-0.17602759399999998,-0.318154173,1.582208888,2.219333444,-5.230429818999999,-5.612887886,-4.48960363,-5.108792053,-5.642150063,-5.298715462,-5.565565725,-1.803216797,-7.599033355712891,-7.598687648773193,-7.930955410003662,-7.550978660583496,-6.7513251304626465 -3598,3598,K213M,0.006604575,-0.15942019699999999,0.010453651,-0.087290634,-0.081841882,0.016794286000000002,-0.032583164,0.045792314,0.042558693,-0.045258125,-0.273582268,-0.040088252000000005,0.060995553,-0.143273821,-0.031307446,-0.001696465,-0.161987298,1.2318136990000002,2.464042643,-6.675834474,-6.421432082999999,-7.11862001,-7.143290604,-5.766055077000001,-6.929774597000001,-6.304795747999999,-3.081565898,-7.403608798980713,-8.87382698059082,-8.347617149353027,-8.977230072021484,-7.4172539710998535 -3599,3599,K213L,0.025181031,-0.086228993,-0.028927476,-0.061253981,-0.065453657,0.015990426999999998,0.008466267,0.041895795,-0.032267474,-0.057560413,-0.11489757199999999,-0.091096869,0.033241917999999995,-0.150545396,0.028037435,-0.048820808,-0.08208650599999999,1.376014197,2.397550292,-5.935441881,-6.614023949,-6.496507126,-6.481012634,-4.81433976,-5.271325935,-4.674511744,-1.8180383919999998,-7.383403778076172,-8.720160484313965,-8.061117172241211,-8.983405113220215,-7.567685127258301 -3600,3600,K213N,-0.089979663,-0.012241861000000001,-0.012068771,-0.060090547,-0.186996305,0.086103208,-0.061134047000000004,-0.118825278,0.085260904,-0.021159107000000003,-0.003324615,-0.024470464,0.00033292300000000005,-0.033508853,-0.086672241,-0.136925546,-0.237067064,1.3746676340000001,2.212412636,-4.832694496,-4.976177658,-4.616900757,-4.787181488,-4.922033508,-4.86117907,-4.501866209,-2.57157995,-6.131436347961426,-7.225095748901367,-6.564066410064697,-7.9789719581604,-6.443439483642578 -3601,3601,K213Q,-0.015278683999999999,-0.076341173,-0.008285411999999999,-0.055855318,-0.025008602,0.09371028599999999,-0.047910956,0.017353589,-0.063216884,0.009541311,-0.162223657,-0.08714373,0.070572907,-0.082309431,-0.029401205,-0.007278849,-0.042738354000000006,1.261582466,2.575244322,-1.9786707019999998,-2.288034515,-2.142881973,-1.5027694930000002,-1.9847999040000002,-1.9748676219999999,-2.508709203,0.117217461,-5.236949920654297,-5.245675086975098,-4.798952579498291,-5.494968414306641,-4.8284406661987305 -3602,3602,K213P,-0.024254219,-0.052874837,-0.008872558000000001,-0.7485809520000001,-1.6882376590000001,-0.030568129,-0.050218884000000005,0.0017104470000000001,0.005628591999999999,-0.054400883,-0.05134879,-0.081875193,0.064130078,-0.698163051,-0.798998853,-1.9208966969999999,-1.455578621,1.88781494,1.446317176,-7.686393495,-8.61217141,-7.046088821000001,-8.342218857,-8.120347824,-6.311140564,-5.160410751000001,-1.688346359,-7.023195266723633,-9.27357006072998,-5.761147499084473,-9.13893985748291,-7.449482440948486 -3603,3603,K213S,-0.033554747999999995,-0.112730859,-0.054055368,-0.08523899800000001,-0.210462363,0.022463145,-0.049779733,-0.017329763,-0.053209941,-0.073735009,-0.15172670800000002,-0.127771128,0.019660392,-0.146644745,-0.023833251,-0.195972498,-0.224952227,1.601294,2.249501175,-4.842875447,-5.221908378999999,-4.363752487,-5.97295192,-4.4792276310000005,-4.176536819,-4.0569065669999995,-1.16667883,-5.396892547607422,-7.880122184753418,-5.647541046142578,-7.236089706420898,-5.752662658691406 -3604,3604,K213R,0.004328584,-0.116185645,-0.017120396,-0.071587252,-0.106634552,0.032437935,-0.030872697,0.039529864,-0.003409626,-0.048121587,-0.18424970300000001,-0.07952947099999999,0.045288679000000005,-0.113395347,-0.029779157,-0.043313758,-0.169955346,1.341771716,2.396205698,-2.109068019,-2.194177094,-1.511185623,-2.21711116,-2.704723122,-1.918143097,-2.253224271,-0.381619386,-5.9502644538879395,-5.833100318908691,-6.227577209472656,-5.643326759338379,-5.161547660827637 -3605,3605,K213T,-0.003800431,-0.11814950199999999,-0.042123152999999997,-0.107751964,-0.34256764799999995,-0.030608528,-0.034572454,0.026971593,0.00897727,-0.069201707,-0.167097296,-0.11203478900000001,0.027788484,-0.15685553,-0.058648398,-0.317751508,-0.367383788,1.880909051,2.3076284780000003,-4.364389534,-4.624284889,-3.9887894360000002,-5.025066475,-4.835754486,-3.348052383,-3.786917955,0.5366438379999999,-3.198108673095703,-6.180656909942627,-5.133489608764648,-6.887565612792969,-4.404031276702881 -3606,3606,K213W,-0.011197468,-0.11009455900000001,-0.001042801,-0.08644534300000001,-0.888566052,0.012762207,-0.047339049,0.024944114,-0.001451958,-0.025156854,-0.19503226399999998,-0.04527788,0.04319227900000001,-0.14281291699999998,-0.030077769,-0.654186269,-1.122945835,1.475636515,1.739286291,-9.179618146000001,-8.804640762,-8.873613387999999,-9.950220657000001,-9.740918976,-8.528696945,-7.32498848,-4.7766310260000004,-12.158872604370117,-12.825846672058105,-11.733211517333984,-12.64327621459961,-10.444316864013672 -3607,3607,K213V,-0.00819853,-0.13202287,0.0026572909999999996,-0.060309681,-0.120524299,0.025235333,-0.060945180999999994,0.044548120999999996,0.09733406,-0.040569377999999996,-0.223476361,-0.074666039,0.07998062,-0.111723373,-0.008895989,-0.028620736,-0.212427862,1.437898184,2.544978656,-5.829983011,-6.673829963999999,-5.570718987,-6.193807259,-5.361053711,-5.350505135,-3.977251865,-0.8504253070000001,-6.630552291870117,-8.258782386779785,-5.964776992797852,-8.14859676361084,-6.856292724609375 -3608,3608,K213Y,-0.014506305,-0.020949266,-0.016262078,-0.086895418,-0.370230613,-0.07390860099999999,-0.033598522,0.004585913,0.076938397,0.043812637,-0.085711168,-0.081810806,0.049286650999999994,-0.125739772,-0.048051063,-0.27119034399999997,-0.46927088100000003,1.5859954440000001,2.1229941,-9.269448645,-8.94075174,-9.488941994,-9.553125488,-9.203682014,-9.160741989,-6.589973815,-2.487493147,-10.415303230285645,-10.427224159240723,-9.895408630371094,-10.897000312805176,-8.819090843200684 -3609,3609,V214A,0.103469719,-0.06806686299999999,0.006739146999999999,-0.041598242,-0.908327702,-0.09338211,-0.030418188999999998,0.237357627,0.040009223,-0.005170654,-0.13096307199999999,0.057627902,-0.044149609000000006,-0.025906982999999998,-0.057289501,-0.701972595,-1.114682809,0.6922216990000001,1.391063252,-9.425958092,-11.22896339,-9.883159546,-9.222745834,-10.04943343,-6.745488251,-7.318838417,-3.2048203280000003,-7.830992698669434,-8.829594612121582,-7.903232574462891,-7.673857688903809,-8.309028625488281 -3610,3610,V214C,0.128454407,-0.013210372,-0.006862655,-0.049724385999999995,-1.214542094,-0.169356764,-0.049352138,0.306260952,0.086995111,0.060512208,-0.086932952,0.06733347599999999,-0.081058785,0.009478475,-0.10892724599999999,-1.335413716,-1.0936704720000001,0.574288409,1.32060653,-14.14139774,-14.95517565,-13.69034844,-16.29258829,-14.51256151,-11.25631479,-8.042179142,-3.360444673,-9.926898002624512,-11.527046203613281,-10.593729972839355,-11.481517791748047,-11.356000900268555 -3611,3611,V214E,0.032427615,0.028456857000000002,-0.013368413,-1.339504054,-2.109988078,-0.24998505699999998,-0.088134327,0.152989556,0.09789304900000001,0.072323169,-0.015409455,0.06617946,-0.092916285,-1.15709362,-1.5219144880000002,-2.147511496,-2.07246466,2.159376204,1.44182232,-14.87652119,-17.13341249,-13.47086801,-16.36504733,-15.01292077,-12.40035735,-8.076400778,-3.2977796130000003,-10.85910415649414,-13.321521759033203,-12.683666229248047,-13.09459114074707,-12.032302856445312 -3612,3612,V214D,0.196656827,0.008466308,-0.812161448,-1.635626594,-2.437506033,-0.181755814,-0.016722644,0.41003629700000005,0.07109362799999999,0.006510743,0.010421871999999999,-0.7933696379999999,-0.830953257,-1.628462546,-1.6427906419999998,-2.567727899,-2.307284166,2.309067694,1.166332926,-14.09325238,-16.59904484,-12.59197234,-16.41132438,-12.82650069,-12.03741968,-6.62172962,-1.371819205,-10.50660514831543,-12.217463493347168,-12.456125259399414,-12.422869682312012,-12.629602432250977 -3613,3613,V214G,0.135999666,0.125165133,-0.0021961570000000002,-0.026279262999999997,-1.505191289,-0.141613456,-0.021778916000000002,0.293778247,0.085887579,-0.007253233,0.257583499,0.050881199,-0.055273512999999996,0.020696567,-0.073255093,-1.733879823,-1.276502754,0.8861056270000001,1.316093513,-14.08940724,-16.32003336,-13.74047269,-14.54197408,-14.23210054,-11.61245554,-8.0828271,-3.968211756,-9.630969047546387,-11.593162536621094,-9.332391738891602,-10.742385864257812,-11.166871070861816 -3614,3614,V214F,0.153119801,0.01782571,0.011464809,-0.201724934,-1.659114328,-0.11851063,-0.02972592,0.335965521,0.086995111,0.060206172999999995,-0.024554753999999998,0.098082042,-0.075152425,-0.11401696800000001,-0.2894329,-1.9827012469999998,-1.335527409,0.834207652,1.301325903,-12.9975101,-12.42374341,-12.266120599999999,-15.80780328,-13.42445661,-11.06542662,-6.61677546,-0.232627479,-10.696629524230957,-7.499762535095215,-11.512165069580078,-8.680253028869629,-8.584383964538574 -3615,3615,V214I,0.19241111,0.011660193999999999,0.035006453,-0.043875689,-0.826021427,0.094481436,0.020544786000000002,0.364277433,0.113342206,-0.06007017,0.083390558,0.017617798,0.052395107,-0.086320422,-0.001430955,-1.201677035,-0.450365819,0.969217636,1.374080915,-5.329401816,-5.0905515669999994,-5.38318959,-5.521711868,-5.9283785170000005,-4.723177536000001,-5.85885611,-1.10919555,-4.757930278778076,-4.647957801818848,-6.874644756317139,-5.298591613769531,-6.415518760681152 -3616,3616,V214H,0.164253492,-0.051812403,-0.045344207000000004,-0.005308875,-1.462711156,-0.155865585,-0.048269779000000006,0.37677676299999996,0.12175721699999999,0.036396937000000004,-0.140021742,0.04080411,-0.131492524,0.078917297,-0.089535046,-1.723670917,-1.201751394,0.63065412,1.307369422,-15.09786283,-15.31813455,-12.79859322,-18.93543587,-15.74435675,-12.69279376,-7.774933309,-2.388515249,-10.505061149597168,-13.00052261352539,-12.785440444946289,-12.551531791687012,-12.588452339172363 -3617,3617,V214K,0.09647540800000001,0.187257332,0.039240734,0.011664635,-1.159835975,-0.179984786,-0.054419975999999995,0.247370792,0.098657249,0.079194421,0.295320243,0.10572986699999999,-0.027248400000000002,-0.047426376,0.07075564599999999,-1.685661734,-0.634010216,0.6170794039999999,1.3087740540000001,-14.28457821,-14.45524024,-13.02119846,-15.77273214,-15.08670715,-13.08701306,-8.687305182000001,-4.468006979,-9.277804374694824,-13.866239547729492,-13.399635314941406,-13.04937744140625,-12.685811042785645 -3618,3618,V214M,-0.014596901,0.125501698,0.017432943,-0.114936464,-0.464651373,-0.12101261099999999,-0.06604575,0.036851947999999995,0.086607953,0.023636742000000002,0.22736665399999997,0.061555162000000004,-0.026689276,-0.105057063,-0.124815864,-0.363081179,-0.5662215660000001,1.510963913,1.967150126,-9.869516022,-9.845264664,-9.777039917,-9.475054024,-10.80744755,-9.442773956,-7.365516443,-3.0221813689999997,-5.857795715332031,-7.926797389984131,-9.391685485839844,-7.613065242767334,-8.15602970123291 -3619,3619,V214L,0.092944827,0.017106408,-0.029466803,-0.0074057490000000005,-0.878103451,-0.113196462,-0.072729657,0.25861931,0.08621499099999999,0.007615047,0.026597767999999997,0.052232889000000005,-0.111166495,0.048011224000000005,-0.062822722,-0.872629788,-0.883577114,0.57354371,1.350739897,-6.695607882999999,-6.817189078999999,-7.052485435,-7.1914408110000005,-6.801784851,-5.615139236,-5.341176435,-0.7693771220000001,-7.43423318862915,-7.461883544921875,-7.548947334289551,-7.1082563400268555,-7.773465156555176 -3620,3620,V214N,0.068592293,3.35e-05,-0.033052461,-0.039471948,-1.332146477,-0.140118209,-0.064374276,0.201558861,-0.009943333,-0.01957715,0.019644071000000003,0.033668362,-0.099773283,0.019130553,-0.09807444800000001,-1.155663248,-1.508629706,0.844150143,1.359234761,-13.27218712,-14.75878712,-13.20789846,-15.36566426,-11.46681667,-11.56176911,-5.967597632,-1.252213472,-7.723530292510986,-11.230487823486328,-10.013526916503906,-10.314380645751953,-11.072425842285156 -3621,3621,V214Q,0.11770275599999999,-0.010632579,-0.034547932,-0.075363309,-1.324416663,-0.13894995400000001,-0.047897580999999995,0.283303093,0.08573288800000001,-0.013698759,-0.007566398,0.019345607,-0.088441471,-0.103763754,-0.046962863,-1.12575038,-1.523082945,1.052896566,1.399277726,-14.42652204,-15.88986733,-13.33045737,-15.43390808,-15.47941604,-11.99896137,-8.658005918999999,-3.79431225,-9.668981552124023,-12.913622856140137,-12.267120361328125,-12.001239776611328,-11.938962936401367 -3622,3622,V214P,0.21113650399999997,-0.062503157,0.00463464,-0.110768725,-1.822061876,-0.15419074900000002,-0.07221206,0.49448506799999997,0.085030479,0.009944313,-0.134950626,0.056723919000000005,-0.04745464,-0.042409115,-0.179128335,-1.738514865,-1.905608886,0.6182098570000001,1.305969224,-13.01993227,-14.62165793,-10.995187800000002,-14.09270338,-12.68381815,-12.70629408,-6.686503849,-2.826672256,-7.5276780128479,-11.509801864624023,-9.486961364746094,-9.383993148803711,-11.258672714233398 -3623,3623,V214S,0.104075111,0.04629708900000001,0.009632855,-0.057298864000000005,-0.8589906820000001,-0.090693064,-0.03481711,0.24296733199999998,0.156909955,-0.053038651,0.14563282800000002,0.076468354,-0.057202645,-0.019105701,-0.095492026,-0.950696575,-0.7672847890000001,0.557047845,1.340162703,-11.28855412,-12.30323379,-11.07611539,-12.95657853,-9.981938995,-10.12490392,-6.399977597,-1.4769532109999999,-6.9553399085998535,-9.725358009338379,-9.308484077453613,-9.211974143981934,-10.21391487121582 -3624,3624,V214R,0.144320888,0.129899359,-0.0027886390000000003,-0.023635369,-1.47282212,-0.11031474599999999,-0.04135916,0.330000936,0.07478641400000001,0.017457398,0.24234131899999997,0.062508309,-0.068085587,0.028402094,-0.075672832,-1.664344795,-1.281299445,0.622770105,1.309578704,-11.12683707,-11.56796969,-8.653530884,-11.838983599999999,-12.97199062,-10.60171056,-6.710822542000001,-2.305187905,-9.576395034790039,-13.237255096435547,-13.055095672607422,-11.109599113464355,-12.885894775390625 -3625,3625,V214T,0.09886749,0.09626871199999999,0.018104244,-0.050957875,-0.246635617,-0.141841874,-0.014406513999999999,0.21214149399999999,0.08672168699999999,-0.006858077,0.1993955,0.011131893,0.025076595,-0.013599675,-0.088316075,-0.19384383,-0.299427404,1.278892809,2.035531171,-5.464224016,-6.614370201,-4.595389771000001,-5.547096565,-6.94885067,-3.615412872,-4.890531343999999,1.550308435,-1.7820134162902832,-5.925881385803223,-4.479588508605957,-5.656883716583252,-8.254355430603027 -3626,3626,V214W,0.07108893200000001,0.087615692,-0.048183923,-0.287164663,-1.630367752,-0.115633716,-0.089192719,0.231370582,-0.021112692000000002,0.026075148,0.149156236,0.050556217,-0.146924062,-0.095960555,-0.47836877,-1.6899437769999999,-1.5707917269999998,0.89689776,1.323301511,-14.154976300000001,-14.447575500000001,-13.13111323,-14.98182317,-13.9961329,-14.21823672,-7.827418092,-2.080117635,-13.42576789855957,-13.33662223815918,-14.413211822509766,-13.287772178649902,-12.587372779846191 -3627,3627,V214Y,0.161194391,-0.020889706,0.001662453,-0.240661438,-1.394818299,-0.065146164,-0.027519221,0.34990800200000005,0.045804940999999995,-0.026984495,-0.014794917,0.058307807,-0.054982900999999994,-0.093495301,-0.387827574,-1.609997062,-1.179639536,0.723590018,1.316221535,-15.89596173,-15.99096864,-14.8390837,-19.35064449,-15.31967547,-13.97943635,-6.561899845,-0.82708322,-11.622329711914062,-11.601360321044922,-12.936283111572266,-11.308828353881836,-10.458492279052734 -3628,3628,A215C,0.023562944,-0.013440298,0.070899622,-0.681506457,-1.5625656909999999,-0.094959911,0.075448236,-0.028322349,-0.016777615,-0.040324055,0.01344346,0.04469461,0.09710463300000001,-0.629959857,-0.733053057,-2.079637179,-1.045494202,1.706779949,1.3561865919999998,-10.98108636,-10.7267995,-12.53864843,-10.939690800000001,-10.19376569,-10.506527400000001,-6.966079927000001,-3.612432913,-8.757243156433105,-9.63191032409668,-9.917470932006836,-8.939312934875488,-9.272090911865234 -3629,3629,A215E,-0.042314189,-0.031344694,0.05873992,-0.437744951,-1.277329484,-0.132678514,-0.039097947,-0.045530430999999996,-0.061269467,0.01547167,-0.078161057,0.157584051,-0.040104211,-0.41002907200000005,-0.46546083,-1.626045037,-0.9286139309999999,1.58480219,1.443726488,-10.44732098,-10.23297678,-11.39757707,-10.73320893,-10.41976097,-9.453081168999999,-7.1900610160000005,-2.9862148389999996,-8.972686767578125,-10.919576644897461,-10.040728569030762,-9.11854076385498,-8.852639198303223 -3630,3630,A215D,0.021827648999999998,0.048333825,-0.8345261070000001,-2.548238304,-2.091308436,-0.087369234,0.08702442699999999,-0.04336913,0.063152507,0.076344507,0.020323142,-0.750874292,-0.918177921,-2.289931955,-2.806544652,-2.162117476,-2.020499395,1.539064424,0.535776915,-10.96955668,-10.88245868,-11.41843651,-11.22696829,-10.97648267,-10.34343727,-5.599776493999999,-0.7365563079999999,-7.280508995056152,-8.860637664794922,-9.409883499145508,-8.227959632873535,-8.58650016784668 -3631,3631,A215G,-0.018948467,-0.0021354810000000003,0.045582685,0.005471770999999999,-0.42454654,-0.089318816,0.000140548,-0.038037482000000004,-0.033388117,0.013221221000000002,-0.017492182,0.11695004,-0.025784671000000002,0.002102707,0.008840834,-0.605429828,-0.243663252,0.819165363,1.443043045,-1.805307565,-2.155460876,-1.3877756730000002,-2.232794205,-1.500159409,-1.750347664,-3.028826243,2.728144354,-4.027171611785889,-4.375652313232422,-3.7699174880981445,-2.874234199523926,-5.878664970397949 -3632,3632,A215F,0.011324236000000001,0.040074227000000004,0.019395251000000002,-1.433333779,-1.90507016,-0.038972507999999996,0.129905689,-0.107257218,-0.049421677000000004,0.09966261,-0.019514157,0.082018933,-0.043228431,-1.8356735830000002,-1.030993975,-2.184980359,-1.62515996,0.6966364820000001,0.6785079959999999,-15.70080672,-15.17814287,-17.85481683,-15.74475196,-16.02049361,-13.70582833,-6.476577239,-2.007364541,-10.548980712890625,-13.342864990234375,-11.493125915527344,-11.296204566955566,-10.586156845092773 -3633,3633,A215I,-0.066446244,-0.041434982999999995,-0.041298302,-2.2483158,-1.728916565,0.011638128000000001,-0.054484942,-0.078407546,0.02914688,-0.07536680400000001,-0.0075031609999999995,-0.063925507,-0.018671097,-2.05416869,-2.44246291,-1.8014154759999998,-1.656417654,0.741039514,0.648722835,-11.90453562,-12.38342065,-13.84775199,-9.127097649,-12.03987695,-12.12453085,-7.139822205,-3.3889831960000003,-10.419698715209961,-11.896135330200195,-11.105570793151855,-9.762784004211426,-8.416930198669434 -3634,3634,A215H,0.058867624,0.086784989,0.059561607999999995,-0.31565459,-1.550710905,-0.103826555,0.05734369,0.060391558,0.02464171,0.077364732,0.096205246,0.12736731699999998,-0.008244102,-0.212239683,-0.41906949600000004,-2.041073784,-1.060348026,1.126547155,1.310877743,-13.65726951,-13.22027788,-14.31032695,-13.23880022,-12.87348872,-14.64345377,-6.508266357,-2.214085071,-9.979948043823242,-10.270167350769043,-11.50915241241455,-11.070978164672852,-11.567194938659668 -3635,3635,A215K,-0.07237293,0.018382935,0.019289136999999998,-0.232453701,-1.870409311,-0.156284342,0.013972439,-0.158718298,-0.070237752,0.014033608000000001,0.022732262000000003,0.175299085,-0.136720812,-0.170822762,-0.294084639,-2.122189529,-1.618629093,0.9896520870000001,1.299190247,-10.60752401,-11.37804474,-11.92988868,-9.31729174,-10.40679529,-10.00559961,-6.466888514,-2.477148377,-8.61494255065918,-12.174079895019531,-11.857551574707031,-10.943817138671875,-10.444109916687012 -3636,3636,A215M,-0.08389416599999999,-0.059637207000000005,0.15463194800000002,-1.654397572,-1.50909235,-0.001800405,-0.053553797,-0.114234535,-0.037445239,0.15087156699999998,-0.27014598100000003,0.255705422,0.053558472999999995,-1.7728827530000002,-1.5359123909999999,-2.122189529,-0.89599517,0.46910384,0.6758235990000001,-12.01662661,-12.93240746,-14.94960044,-10.273307899999999,-12.26865303,-9.659164207,-7.460159527,-3.673600615,-10.536108016967773,-12.162437438964844,-11.314159393310547,-10.194499015808105,-9.921915054321289 -3637,3637,A215L,-0.07608236,-0.026271226,-0.10827483800000001,-1.715166763,-2.504267698,0.070147608,-0.046537164000000006,-0.105627556,-0.044833172000000004,-0.024749331,-0.02779312,-0.10037525900000001,-0.11617441699999999,-1.66785485,-1.762478676,-2.9714041360000003,-2.03713126,1.0043461009999999,0.711978474,-13.96884615,-13.66697993,-17.44785216,-11.05689151,-14.45274866,-13.21975848,-7.647401964,-3.853275579,-10.492166519165039,-12.162883758544922,-11.445174217224121,-10.037116050720215,-8.691020965576172 -3638,3638,A215N,-0.109294524,-0.093327624,-0.06071278099999999,-0.254367584,-1.684866444,-0.09329905699999999,-0.055975707,-0.162613341,-0.055174006,-0.12979047300000002,-0.056864775,0.071303468,-0.192729029,-0.148315421,-0.36041974600000004,-1.48786236,-1.881870528,1.087760286,1.35943796,-10.59041736,-10.82385738,-11.98496444,-10.14614839,-8.913172142,-11.08394446,-5.1454684969999995,-0.7952781059999999,-8.345850944519043,-7.337291240692139,-9.23630142211914,-8.210031509399414,-8.160147666931152 -3639,3639,A215Q,0.047340227,-0.016899200000000003,-0.006710984000000001,-0.314523183,-2.01652056,-0.084776385,0.063424225,0.031256228,-0.07783799,-0.02274379,-0.01105461,-0.02375454,0.010332573000000001,-0.368312165,-0.2607342,-2.2361328819999997,-1.796908238,1.46450957,1.298843281,-10.94861969,-11.13708069,-11.75186317,-10.73216604,-10.39005102,-10.73193754,-6.135161753999999,-2.579041529,-10.12812614440918,-11.335293769836426,-11.399930953979492,-10.041625022888184,-11.103002548217773 -3640,3640,A215P,-0.016448781000000003,0.043188129000000006,0.044296746,-0.402080592,-1.5563334,-0.105342384,0.011024903,-0.043922464,-0.041923683999999996,0.028240769,0.058135488,0.11310813800000001,-0.024514647,-0.34427861299999996,-0.459882571,-1.799528355,-1.313138445,1.450491059,1.382997745,-10.82438518,-11.11246517,-11.72284933,-10.33510964,-10.10185222,-10.84964953,-7.43306654,-3.673600617,-8.238273620605469,-10.97172737121582,-9.894365310668945,-7.470292091369629,-10.280757904052734 -3641,3641,A215S,0.019278083,0.014809262,0.075964766,0.073168095,-0.430107826,-0.10242640900000001,0.061736669,-0.023180503999999998,-0.028347981,0.07728183,-0.047663307,0.147774242,0.00415529,0.10158317900000001,0.04475301,-0.55778291,-0.302432741,0.471449348,1.377525086,-5.247889478,-5.622802322,-5.6264218370000005,-5.8872985,-4.520085388,-4.58283934,-3.983585836,0.407801727,-4.77866268157959,-5.436744689941406,-5.1895341873168945,-4.670220851898193,-4.409852504730225 -3642,3642,A215R,-0.009886063,-0.035762112,0.036737023,-0.39130344200000006,-1.642443334,-0.099139037,0.000167614,-0.01993974,-0.009045876999999999,0.00727928,-0.07880350400000001,0.119521445,-0.046047399,-0.331798869,-0.450808015,-1.858948095,-1.425938572,1.427829104,1.36357387,-12.20885485,-12.51672195,-12.92003445,-11.36292719,-10.84275133,-13.40183932,-6.441073371,-1.583870406,-9.855911254882812,-11.640525817871094,-11.258204460144043,-9.916851043701172,-11.366384506225586 -3643,3643,A215T,-0.007732291999999999,-0.017173671,0.049608933,0.036441615,-1.243536899,0.081948903,0.05735765599999999,-0.072822239,-0.033854659,0.013873085,-0.048220427,0.135876805,-0.03665894,0.067512689,0.00537054,-1.4241835530000002,-1.062890245,0.485960664,1.313179273,-4.921768552,-5.408876144,-5.351601028,-5.982999657000001,-4.379944298,-3.4854216310000004,-3.806535484,-0.906021656,-7.788469314575195,-8.3624267578125,-7.96870231628418,-6.689722061157227,-6.003294944763184 -3644,3644,A215W,-0.141502671,-0.10599767,-0.37146928100000004,-1.896191995,-1.844041984,0.04633253,-0.091339664,-0.19166567699999998,-0.11644366199999999,-0.0020958929999999997,-0.209899447,-0.281158969,-0.461779593,-2.402971468,-1.389412521,-2.7522782439999998,-0.9358057240000001,0.927137957,0.446977464,-15.14971063,-14.23621075,-16.65526324,-14.77770676,-13.62365913,-16.45571325,-6.245466459,0.253314258,-13.257827758789062,-14.613240242004395,-12.585550308227539,-13.63564395904541,-13.477228164672852 -3645,3645,A215V,0.025584387000000004,0.012245352,0.09173098699999999,-0.806085664,-1.7898338569999999,-0.030929356,0.069006949,-0.017838176,-0.020486978,0.024569802999999998,-7.91e-05,0.15498900599999998,0.028472967999999998,-0.7872805740000001,-0.8248907529999999,-1.784947361,-1.794720352,2.065604958,1.5792932519999998,-9.204069029,-10.4230806,-10.54235567,-7.129606658999999,-9.45711795,-8.468184265,-6.91527874,-3.620203055,-9.380491256713867,-9.741708755493164,-8.856853485107422,-7.952970027923584,-6.339541912078857 -3646,3646,A215Y,-0.017559171999999998,-0.053796610999999994,0.060525632999999995,-0.938298511,-2.06100181,-0.136957918,0.040844585,-0.075962929,0.007381498,0.008281279,-0.11587449999999999,0.12623600199999999,-0.005184737,-0.8865404790000001,-0.990056543,-2.349790608,-1.7722130109999998,0.8328326890000001,0.78501274,-16.700724599999997,-15.35069089,-17.99366364,-17.34643345,-15.98576097,-16.82707406,-6.8414549739999995,-1.49115889,-11.046037673950195,-13.168050765991211,-11.753483772277832,-11.299457550048828,-10.770977973937988 -3647,3647,G216A,-0.0028913890000000003,-0.006613634,0.000318167,-0.01109758,-0.310987193,-0.038288444,-0.032719569,0.026936792,-0.025029696,0.010363698000000001,-0.023590965,0.023572599,-0.022936265,0.016845493,-0.039040653,-0.24666417,-0.375310215,1.228768595,1.90874274,-4.123762885,-3.940602737,-3.436713722,-3.426140205,-5.930458351,-3.884899406,-4.275803052,0.067327612,-5.384866714477539,-4.792524337768555,-8.41606330871582,-6.817307472229004,-6.447445869445801 -3648,3648,G216C,-0.011777837,-0.08825125199999999,-0.006519942,0.013217701,-1.719736905,-0.09907958,-0.05279452900000001,0.029238856,0.041375562000000005,0.011062221,-0.187564725,-0.005469315,-0.007570569,0.026200743,0.00023465900000000002,-1.43248083,-2.00699298,0.569565963,1.315662319,-9.829597905,-11.20352809,-10.80347881,-8.38556945,-11.43682791,-7.318585258,-7.799637959,-3.8818279760000003,-10.18743896484375,-10.668994903564453,-12.82918930053711,-12.837769508361816,-11.11931037902832 -3649,3649,G216E,-0.023045445,-0.036870406,-0.115991916,-0.024259738,-1.070069416,-0.13970165,-0.065499025,0.019408136,-0.148698421,-0.008425086,-0.065315725,-0.19403489999999998,-0.037948931,-0.038235865,-0.010283611,-0.951825114,-1.188313717,1.0615992429999999,1.43270767,-5.958552121,-6.413950066,-7.316737862,-5.349125526,-4.8617041930000005,-5.851242957999999,-5.4299773579999995,-0.7910148090000001,-5.783394813537598,-6.0214104652404785,-8.131014823913574,-7.363517761230469,-5.735610008239746 -3650,3650,G216D,0.0064812690000000004,-0.020265753,-0.031938171,-0.068140823,-1.1015153979999999,-0.05232578400000001,-0.001308344,0.014270882,-0.027285776,-0.013603513000000001,-0.026927992,0.0032921559999999996,-0.067168498,-0.084767056,-0.05151459,-1.155964158,-1.047066638,1.02220432,1.38932045,-2.761740132,-2.667551071,-5.886782516,-2.29176622,-1.8314968409999999,-1.131104012,-2.536583793,1.03013546,-3.6424007415771484,-5.723869323730469,-6.9726691246032715,-5.676479816436768,-4.988508224487305 -3651,3651,G216F,0.127374983,0.057259415,0.035869193,0.108238986,-1.497825789,-0.081839521,0.139418061,0.115331905,0.05605143,0.016685635,0.097833195,0.054808714,0.016929671,0.068867079,0.147610892,-1.311081595,-1.684569982,0.574924068,1.3230950879999999,-9.735053555,-10.67012408,-10.90055251,-7.286821892000001,-13.1344863,-6.683282997,-6.430951117999999,-3.5793459739999998,-8.818796157836914,-10.828590393066406,-10.641733169555664,-12.225513458251953,-10.330409049987793 -3652,3652,G216I,0.005978926999999999,0.019712228999999998,0.024611876,-0.011751026999999999,-1.730204233,-0.035276787000000004,-0.022130087000000003,0.034087941000000004,-0.034125199999999994,-0.07234532099999999,0.111769779,-0.015229153,0.064452905,-0.012845226000000001,-0.010656828,-1.394692269,-2.065716196,0.602068069,1.319526861,-9.899021825,-10.94562433,-9.961905052,-8.179973145,-12.38141537,-8.026191223,-6.683863313,-3.23999094,-8.314864158630371,-9.67005443572998,-12.08734130859375,-11.515066146850586,-10.513206481933594 -3653,3653,G216H,0.005670523,-0.035751846000000004,-0.022058478,-0.026433043,-0.843535431,-0.056283924000000006,-0.00881639,0.020157436,-0.0060057059999999995,-0.013061298,-0.058442392999999995,-0.011470922,-0.032646034,0.0034251520000000003,-0.056291238,-0.766524205,-0.920546657,0.763675241,1.39781194,-7.512663794,-9.715436852,-8.846412231,-5.664222801,-6.513981887999999,-6.823265198,-6.742360305,-1.530177956,-7.636486530303955,-9.18015193939209,-10.389403343200684,-9.682120323181152,-8.729177474975586 -3654,3654,G216K,-0.083295625,0.021156261000000003,-0.06517661200000001,0.020580031999999998,-0.637357076,-0.10686667300000001,-0.132387739,-0.034203511,0.187723549,-0.0061226580000000004,0.04843518,0.007167079,-0.13752030199999998,0.034882581,0.006277481999999999,-0.46360385299999995,-0.811110298,0.81836707,1.4904648669999998,-5.536546777000001,-7.198613495,-4.545164421,-5.202698227,-5.436162453,-5.300095291,-5.125700086,-0.144154606,-6.036730766296387,-6.836491107940674,-10.788725852966309,-9.367353439331055,-8.785846710205078 -3655,3655,G216M,-0.088814743,-0.169258512,0.014768267,0.043411705,-0.525735054,0.025537795,-0.10936280300000001,-0.068266683,0.10271276,0.026526262999999998,-0.36504328700000005,0.05120459,-0.021668057,0.08133732099999999,0.005486089,-0.309142236,-0.742327871,1.2462143159999999,1.8597983809999998,-8.505143003999999,-8.082379524,-8.747419228,-6.966036118,-10.62299767,-8.106882484,-6.461383478999999,-2.624256006,-8.713827133178711,-9.102643966674805,-10.573391914367676,-10.744938850402832,-10.391063690185547 -3656,3656,G216L,0.006812556,-0.069455419,-0.009667596,-0.017054918999999998,-0.765563344,-0.060545044000000006,-0.018732923999999998,0.032358035,-0.032882583,-0.009582239000000001,-0.12932859800000002,0.017036847,-0.036372037999999995,-0.012574591999999999,-0.021535245,-0.640059523,-0.891067165,0.8851020059999999,1.456194861,-7.2345199860000005,-7.648190102,-8.041867706,-6.513365547,-9.087525932,-4.881650642,-5.298610443,-0.927385833,-8.039905548095703,-8.180373191833496,-8.48757266998291,-10.263882637023926,-9.775383949279785 -3657,3657,G216N,-0.055483692,0.061163385,-0.09118140300000001,-0.032140943,-0.17146729800000002,-0.01175052,-0.017639547,-0.093327836,0.038425467000000005,-0.074356724,0.19668349300000001,-0.08349398400000001,-0.098868822,-0.078667118,0.014385233,-0.15560012199999998,-0.187334473,1.427809532,2.213852115,-4.98125697,-6.371647972000001,-5.608445777999999,-4.266888374,-5.389413246,-3.2698894810000003,-4.49872886,0.217256034,-5.763057231903076,-6.705779552459717,-8.637781143188477,-7.239709854125977,-6.909148216247559 -3658,3658,G216Q,0.06856371,-0.036985715,-0.0009493860000000001,0.03091792,-0.160168266,0.035652674,0.050177399000000004,0.08695002,-0.106675867,-0.035959431,-0.038011999,-0.015933351000000002,0.014034578999999998,0.028942213999999997,0.032893626,-0.190146979,-0.130189553,1.345179325,2.138992574,-5.3637503539999996,-5.180051253999999,-6.1174476779999996,-4.2504535830000005,-5.4810293660000005,-5.78976989,-5.162203505,-0.943110285,-7.029732704162598,-7.672995090484619,-10.325581550598145,-9.03030014038086,-8.293965339660645 -3659,3659,G216P,0.018835202,0.016392633,-0.012354637,-0.116471786,-1.499187483,-0.105826945,-0.00729243,0.044962833,0.001844382,-0.01607658,0.048861845,-0.024294195,-0.00041507800000000004,-0.08077118,-0.152172392,-1.7481523330000002,-1.250222633,0.858667251,1.316704003,-8.806176485,-7.7755283429999995,-7.824593826,-7.082954658999999,-13.36670285,-7.981102745,-5.359209936,-0.057788978,-8.79625415802002,-8.936261177062988,-11.368130683898926,-10.465511322021484,-10.22297191619873 -3660,3660,G216S,0.012239866,0.046390495999999996,-0.006090613000000001,0.007996046,-0.7025688729999999,-0.07796723,0.008922055,0.015557676000000001,-0.011791515,0.006466469,0.086314523,-0.017038311,0.004857085,0.00257987,0.013412221,-0.619317663,-0.785820083,0.935288536,1.4824072480000001,-5.430268887,-6.125199554,-5.420694496,-3.9049039839999997,-7.252644257,-4.447902145,-5.0560766930000005,-1.14001398,-5.726231098175049,-6.24035120010376,-8.607444763183594,-7.199389457702637,-6.419495582580566 -3661,3661,G216R,0.018601533,-0.084044105,-0.018486798999999998,0.001997235,-0.9179424359999999,-0.053407795,-0.022573445,0.059776511,-0.012876648000000001,-0.0072348080000000006,-0.16085340199999998,-0.017980875,-0.018992723,-0.00842136,0.01241583,-0.759927791,-1.0759570809999999,0.920282128,1.440236012,-5.578184041,-6.22638884,-5.660751128999999,-5.247268707,-4.796957878,-5.95955365,-4.165581816,0.35492957299999994,-6.816708087921143,-7.699825286865234,-9.968873023986816,-9.874009132385254,-9.87644100189209 -3662,3662,G216T,-0.017409265,0.01468483,-0.029651074,0.0058366569999999994,-0.6573795139999999,-0.082856638,-0.016353305,-0.018465224,-0.024851656,0.011719896,0.017649763,-0.022211206,-0.037090941,0.041773459,-0.030100146,-0.5882838229999999,-0.726475205,0.502090185,1.377211586,-6.122869049,-6.512450737000001,-5.951319,-4.670941513,-8.399427589,-5.080206406,-4.719979186000001,-0.307093202,-6.3907270431518555,-6.7061920166015625,-9.696613311767578,-8.151165008544922,-7.578845024108887 -3663,3663,G216W,-0.054449038,-0.063948116,-0.046229828,-0.060131902,-0.921568061,-0.051959856,-0.072343248,-0.036554827000000005,0.10057337400000001,-0.049306752,-0.078589479,-0.01748621,-0.074973446,-0.041762574,-0.07850123,-0.697979322,-1.1451568,0.844221632,1.430358798,-11.01124455,-12.18530641,-10.73918853,-8.987266579,-13.41910608,-9.725355171,-7.578798344,-2.718290917,-9.74746036529541,-10.892477989196777,-12.829998016357422,-13.10136890411377,-11.352058410644531 -3664,3664,G216V,-0.026932497000000003,-0.122627764,-0.037714492999999995,-0.008556777,-1.553889303,-0.10530362,-0.082514931,0.028649937,0.009468925999999999,0.016861991,-0.262117518,-0.013586282,-0.061842704000000005,0.043027867000000004,-0.060141420999999994,-1.57385276,-1.533925845,1.0812690120000001,1.352034995,-8.211486241,-9.392539841,-8.385290741,-6.367401382000001,-10.45328177,-6.458917473,-5.611465905,-1.929282358,-7.655517101287842,-8.259834289550781,-10.607691764831543,-9.812297821044922,-9.567665100097656 -3665,3665,G216Y,0.02549871,0.047522568,0.0019462129999999998,-0.032947085,-1.2191909140000001,-0.100783052,0.005091310999999999,0.045906108,-0.00112494,0.003353234,0.09169190099999999,0.008737766,-0.00484534,-0.06392529799999999,-0.001968872,-1.345843701,-1.092538127,0.918759923,1.3504608009999999,-10.12734793,-12.94919798,-11.99416805,-7.097282097000001,-11.83584721,-6.760244347,-6.549859934,-2.9263482639999996,-8.294710159301758,-10.82847785949707,-11.250346183776855,-11.477154731750488,-9.467223167419434 -3666,3666,P217A,-0.035104257,-0.016601721,-0.017223525,-0.0034384059999999998,-0.049668195,0.096735715,-0.021249645,-0.048958867999999996,0.0074137180000000006,0.037359775,-0.070563217,0.035803087000000004,-0.070250137,0.026097961,-0.032974773,-0.041158396,-0.058177994000000004,1.265315663,2.4962177690000003,-2.509097375,-1.322061172,-3.2529039460000004,-2.847630005,-2.675889229,-2.447002525,-3.9225392880000003,1.429935895,-5.083536624908447,-4.959114074707031,-2.687894821166992,-5.416718482971191,-5.45695686340332 -3667,3667,P217C,-0.03297198,0.013342314,0.055138155999999994,0.01055482,-0.9434368390000001,-0.010828974,-0.054952272,-0.010991687,0.014776965,0.053212812000000005,-0.026528185,0.12290643,-0.012630118000000001,0.044197337,-0.023087697,-0.792481887,-1.09439179,0.6859697920000001,1.3773619540000002,-9.18079593,-8.099236937999999,-9.852977585,-9.715291191,-10.13222026,-8.104253677,-8.335996678999999,-2.626039084,-10.167411804199219,-12.107656478881836,-9.97908878326416,-11.466896057128906,-11.865287780761719 -3668,3668,P217E,0.06100943599999999,0.012347592,0.054936907,0.0027713629999999998,-0.29422413399999997,-0.079384828,0.014580248,0.10743862300000001,-0.053512758,0.054661855999999995,-0.029966672000000003,0.062797928,0.047075886,-0.008081664,0.013624388999999999,-0.160516883,-0.42793138399999997,1.332849414,2.129928596,-4.446299245,-2.9921253660000002,-5.265222672,-6.406227058,-3.8163946,-3.7515265269999998,-4.444484508,1.1872475120000001,-5.402469635009766,-7.381054401397705,-4.669769287109375,-5.654474258422852,-6.627145767211914 -3669,3669,P217D,-0.02491113,0.078210747,0.021723402000000003,-0.004205715,-0.149352214,-0.107600285,-0.05954381,0.00972155,0.06153162400000001,0.08794054,0.06848095400000001,0.083625885,-0.040179082000000005,0.056678595,-0.06509002400000001,-0.100276332,-0.19842809600000003,1.420615056,2.563955177,-3.31890733,-1.6444342730000001,-4.038151077,-6.087297119,-3.242029198,-1.582624985,-3.558855804,1.6749039940000001,-4.696640491485596,-7.528151035308838,-4.934554576873779,-4.88973331451416,-5.790249347686768 -3670,3670,P217G,0.013693307,-0.044341877,-0.015918068,-0.007137341,-0.494440349,-0.021776674,0.010901204,0.016485409,0.045176263,0.003845163,-0.092528916,-0.000115875,-0.03172026,-0.006212095,-0.008062586,-0.366362474,-0.6225182229999999,1.061542465,1.65479138,-3.770486748,-2.233006462,-4.8862147369999995,-5.027651802,-4.401579315,-2.3039814219999997,-5.22758833,0.579268462,-4.769795894622803,-6.729551792144775,-4.5656304359436035,-5.500182628631592,-5.478147506713867 -3671,3671,P217F,-0.052804572,-0.045092675,-0.065338427,-0.054681412,-1.509183144,-0.00678853,-0.06963878,-0.035970364,-0.057063154000000005,-0.06341561,-0.026769739,-0.077993005,-0.052683848,-0.044978834,-0.064383989,-0.941737365,-2.076628922,0.929104963,1.40094192,-10.6266267,-10.06115308,-11.17402383,-10.56356091,-11.85814646,-9.476249237000001,-8.004255367,-3.06238992,-9.851503372192383,-11.427083969116211,-7.3466877937316895,-9.684409141540527,-10.06607723236084 -3672,3672,P217I,-0.013264945,0.087849096,-0.018662892,-0.020307091,-1.350092088,-0.03216553,0.015358526,-0.041888415,0.06901248,0.109670733,0.066027458,-0.054743068,0.017417283999999998,-0.024011032999999998,-0.016603148999999998,-1.119493653,-1.5806905230000001,0.7247316770000001,1.347417956,-10.67070695,-9.136974487,-13.18514881,-10.87821847,-10.57610178,-9.577091225,-8.59648343,-3.85100613,-9.049564361572266,-9.373231887817383,-7.114422798156738,-8.756722450256348,-8.624454498291016 -3673,3673,P217H,0.044303155,-0.02325768,0.020875202,0.004635463,-0.221030842,0.03661518,0.043755385,0.044850924,0.031148996,0.018377956,-0.064893315,0.025157897999999998,0.016592505,-0.015666664,0.024937589,-0.212436347,-0.229625336,1.557634929,2.226564484,-6.402804721,-5.672334915,-7.255904861,-7.187190384,-6.970301482999999,-4.928291962,-5.32369567,1.1257424790000001,-6.535755157470703,-8.566914558410645,-6.341557502746582,-6.387608051300049,-7.838011741638184 -3674,3674,P217K,0.062003447,0.08493882,0.020864521,0.061836518,-0.007076838,0.08753975800000001,0.09303560300000001,0.03097129,-0.005324185,0.084030467,0.08584717300000001,0.038888088,0.002840953,0.127049771,-0.003376736,-0.008684155,-0.00546952,1.321668002,2.76236175,-4.2120651989999995,-2.7358317110000003,-5.878951133999999,-4.491291534,-4.05868399,-3.8955676269999997,-4.407592617,1.256034733,-4.858986854553223,-8.439882278442383,-2.1517648696899414,-5.140907287597656,-4.071554183959961 -3675,3675,P217M,-0.096982015,-0.054837605,-0.009540184,-0.11107656199999999,-0.156304504,0.054080464,-0.114283146,-0.07968088400000001,0.0075544769999999995,-0.012247672,-0.097427537,0.09955343400000001,-0.118633801,-0.020604783999999998,-0.201548339,-0.010420327,-0.30218868,1.543610422,3.106887046,-8.48229604,-7.2003639139999995,-10.06263823,-9.163198906,-8.02516124,-7.960117912,-6.955173967,-2.414323691,-8.826494216918945,-7.964934349060059,-6.098371505737305,-8.280303955078125,-8.350704193115234 -3676,3676,P217L,-0.02001265,-0.025505335,-0.012217700000000001,-0.0067684830000000005,-0.541115992,0.034532629,-0.017922259,-0.02210304,-0.000425804,0.02809577,-0.079106439,-0.000674998,-0.023760402000000003,0.000694407,-0.014231373,-0.42074051799999995,-0.661491465,0.939392255,1.563063857,-8.280118896,-7.175396156000001,-9.614958923,-8.850492302000001,-8.040279785,-7.719467316,-7.12814073,-1.350654129,-7.976683616638184,-7.147771835327148,-5.5939788818359375,-6.985741138458252,-8.203014373779297 -3677,3677,P217N,-0.07331183,0.020165346,-0.060433929000000004,-0.031556496,-0.131099892,-0.06999781599999999,-0.019660865,-0.126962794,0.034250374,-0.01054891,0.050879602,0.018582622,-0.13945048,0.020972354,-0.084085345,-0.132451922,-0.129747861,1.347976698,2.242472497,-3.286205981,-1.9394795759999999,-3.857469818,-3.670100899,-4.168489319,-2.795490295,-4.199061503,1.421521764,-4.690937042236328,-6.193028450012207,-4.631958484649658,-5.08831787109375,-5.133912086486816 -3678,3678,P217Q,-0.01108221,-0.011806348999999999,0.023728605,0.00961528,-0.143022174,0.022935068,-0.028996732,0.006832311999999999,0.022993202,0.03311488,-0.056727578,0.042060692000000004,0.005396518,0.031364849,-0.012134289,-0.07008448,-0.215959867,1.414904449,2.54082215,-4.848964154,-3.819085587,-5.977115891,-5.965240929,-4.59165657,-3.891721794,-5.274300252,0.645187404,-5.735536098480225,-7.166011810302734,-4.9584856033325195,-5.907793998718262,-6.167224884033203 -3679,3679,P217S,0.009533891999999999,-0.004407541,-0.017485182,0.039209529,-0.300363106,-0.036414128999999996,0.023960691,-0.004892908,0.000833784,0.02175942,-0.030574502000000003,-0.013075453999999999,-0.02189491,0.05563208099999999,0.022786977000000003,-0.227974003,-0.372752209,1.1757458509999998,1.9506696380000002,-3.674477931,-2.641335014,-4.164132088,-3.84758519,-4.298399139,-3.420938225,-4.906253993,1.033611012,-3.6343235969543457,-5.734711647033691,-4.216294288635254,-4.77815055847168,-5.2317705154418945 -3680,3680,P217R,0.005384054,-0.064369505,-0.00927909,0.006105439,-0.5122000529999999,0.045422297,0.003550502,0.007217605,-0.00388548,0.024073706,-0.152812715,0.002552824,-0.021111003,0.01958839,-0.007377511999999999,-0.36408305700000004,-0.660317049,1.059478962,1.6624555419999998,-6.319127513,-4.357751511,-8.642395096,-8.541373199,-5.643384094,-4.410733665,-7.003257388,0.825908596,-6.0033745765686035,-9.15732192993164,-5.272309303283691,-7.1918182373046875,-6.658911228179932 -3681,3681,P217T,-0.012296521999999999,0.06112032,0.010158154,0.024849086,-0.193910919,-0.016709769,0.0063608630000000005,-0.030953907000000003,0.036944433,0.06377154,0.0584691,0.03635239,-0.016036083,0.030984874,0.018713298,-0.182900399,-0.20492143899999998,1.38706504,2.1532873319999997,-5.020718037,-3.379785507,-6.733288719,-5.3987373960000005,-4.386834358,-5.204944206,-3.8798400280000003,1.272994125,-4.693443298339844,-6.297245025634766,-3.896927833557129,-5.237987518310547,-5.408839225769043 -3682,3682,P217W,-0.002458467,-0.058029986,0.016268091000000002,-0.00227249,-1.924774941,0.01720804,0.005117292,-0.010034226,-0.048123873,0.054608137,-0.170668108,0.039542449,-0.007006268,0.042294497,-0.046839477000000004,-1.6002190319999998,-2.249330849,0.652179761,1.3160173370000001,-10.38073444,-8.452413818,-11.27014333,-11.69978212,-11.45692411,-9.024408836000001,-7.972537725,-2.626039029,-11.438386917114258,-14.201726913452148,-8.474830627441406,-10.942594528198242,-10.470512390136719 -3683,3683,P217V,0.064024997,-0.014537332,0.032537464,0.024850381,-0.281510655,-0.009649058,0.026728988999999998,0.101321004,0.032116244,0.010234696,-0.03930936,-0.021308213,0.08638314,0.02730562,0.022395141,-0.157132265,-0.405889044,1.282950559,2.134169417,-8.920625391,-7.402179199,-11.73463029,-9.305690056,-8.63942498,-7.521202431,-7.082447889,-1.857570271,-7.849582195281982,-8.089132308959961,-5.841736316680908,-7.535422325134277,-7.588078498840332 -3684,3684,P217Y,0.047043569,0.029349611,0.034346435,-0.018649918999999997,-1.0447035359999999,-0.040709913,0.046445674000000006,0.047641462999999995,-0.046219870999999996,0.014122765,0.044576457,0.030737741000000002,0.037955128,-0.045520272,0.008220435,-0.809746545,-1.279660527,0.642309334,1.3657376509999999,-9.076290976000001,-8.287556992,-9.778807709,-9.126171005,-10.49586242,-7.693056755,-6.740915825,-0.886155062,-8.867195129394531,-11.727273941040039,-7.306643486022949,-8.871639251708984,-9.445183753967285 -3685,3685,L218A,-0.034110833,-0.04109114,-0.034370896,-1.573596662,-2.1574896690000003,-0.074077556,-0.066592123,-0.0016295429999999998,0.004778844,-0.040118443,-0.042063837,-0.049298725999999994,-0.019443066000000002,-1.4610414669999998,-1.6861518569999998,-2.022505783,-2.292473555,2.715898052,1.784616108,-11.82753091,-11.06658401,-11.90531981,-12.95222167,-14.47699582,-8.736533218,-6.877561983,-2.870603811,-8.225189208984375,-9.717570304870605,-8.843255043029785,-9.376604080200195,-12.909082412719727 -3686,3686,L218C,-0.08650015800000001,-0.020835752,-0.07063399,-0.9677473129999999,-1.8879856640000001,-0.030762592000000002,-0.10341442199999999,-0.06958589400000001,0.126250374,-0.045633214000000005,0.003961711,-0.068732608,-0.072535371,-0.517643752,-1.417850874,-2.071440627,-1.7045307,1.691891293,1.367684752,-11.04510899,-8.708488396,-11.26071796,-12.6633233,-13.45234252,-9.140672752,-6.760660675,-2.497484833,-11.718806266784668,-13.18212604522705,-10.980795860290527,-12.202317237854004,-15.816924095153809 -3687,3687,L218E,-0.036320597,-0.022625097,-0.680249856,-1.780352837,-2.809141168,-0.142126885,-0.068498151,-0.004143043,0.042494168,-0.028148711,-0.017101483,-0.715149521,-0.645350191,-1.891297807,-1.6694078669999999,-2.656882106,-2.96140023,1.972674251,0.8676063629999999,-14.649134099999998,-14.14951814,-13.68281259,-16.15465314,-17.98563412,-11.27305253,-8.236131653,-2.817413684,-7.9930033683776855,-13.167491912841797,-9.84906005859375,-12.113067626953125,-15.389689445495605 -3688,3688,L218D,0.023469782999999998,-0.070989311,-0.091439376,-1.788551701,-1.649850489,-0.128680764,0.034667892,0.012271674,0.106759286,-0.048510595999999996,-0.093468025,-0.083999511,-0.09887924,-1.671686814,-1.905416588,-2.0624549030000003,-1.237246074,1.0044752259999998,0.712251304,-17.48504528,-15.11093855,-20.59971222,-19.56408167,-18.87847422,-13.27201973,-8.78994063,-3.482839062,-9.132266998291016,-13.64483642578125,-10.087888717651367,-12.744647979736328,-16.745737075805664 -3689,3689,L218G,-0.032382493,-0.04383445,-0.034613908,-1.504824648,-2.040364951,-0.11223298300000001,-0.044399197,-0.020365788,-0.017982776000000002,-0.057942888,-0.029726011,-0.05268033900000001,-0.016547476999999998,-1.396199891,-1.613449405,-2.198213455,-1.882516446,0.932425368,0.734638385,-14.007753699999999,-13.32759182,-12.2119784,-16.0877579,-17.87385423,-10.53758617,-7.04881436,-1.9398267980000001,-9.024250984191895,-12.09564208984375,-8.366537094116211,-10.844629287719727,-14.467559814453125 -3690,3690,L218F,-0.09902433,-0.047278677000000005,-0.023279547,-1.727729377,-2.233060674,-0.075599776,-0.085095553,-0.112953106,-0.03698062,-0.048462299,-0.046095054,-0.005057956,-0.041501137,-1.485065528,-1.9703932259999999,-2.301802349,-2.1643189990000002,0.952540715,0.7300441959999999,-9.634879424,-8.110473755,-10.8925898,-10.92467815,-9.719133072,-8.527522338999999,-8.101519885,-4.0820173969999995,-8.253863334655762,-9.196402549743652,-8.10997200012207,-8.378961563110352,-10.026802062988281 -3691,3691,L218I,-0.010461264,-0.015606700000000001,-0.034513271,-0.21312514,-1.350570111,-0.053618331,0.021849952000000002,-0.042772479,-0.129267703,-0.112977494,0.081764095,-0.102610519,0.033583978,-0.168047427,-0.258202852,-1.829882288,-0.871257933,1.246472262,1.341526937,-8.733722961,-8.553791061,-7.460346213999999,-10.24869703,-9.959099205,-7.4466812970000005,-8.163864795,-2.403246097,-7.2886457443237305,-8.888541221618652,-8.03722858428955,-6.759844779968262,-9.479472160339355 -3692,3692,L218H,-0.002556199,-0.027350066,-0.169681127,-1.7178171269999998,-2.623540895,-0.075591185,0.005930673000000001,-0.011043071000000002,0.060854177,-0.05856037099999999,0.00386024,-0.225765347,-0.113596907,-1.726155729,-1.709478525,-2.412558781,-2.8345230089999998,1.2732007490000001,0.7359063770000001,-13.53327335,-11.32437807,-14.51921588,-16.22522029,-13.82624717,-11.77130534,-8.242263906,-4.099427563,-9.109713554382324,-11.13962173461914,-8.098139762878418,-10.534799575805664,-13.748567581176758 -3693,3693,L218K,-0.039520723,0.005233643,-0.777621553,-1.821604501,-2.5606165069999998,-0.11779410400000001,-0.012516916000000001,-0.06652453,-0.108171992,-0.053374829000000006,0.063842114,-0.918312556,-0.636930549,-1.673197405,-1.970011596,-2.489934226,-2.631298787,2.628416573,1.358083519,-9.306860046,-10.09038832,-7.127389343,-9.932597824,-10.61110559,-8.772819153,-6.032343238999999,-0.432725376,-7.492009162902832,-11.350443840026855,-8.267572402954102,-10.322783470153809,-13.412605285644531 -3694,3694,L218M,0.01391873,0.009697374,0.02547685,0.036105148,-0.36244186700000003,0.005535481,0.036833676,-0.008996216,-0.036881454,0.018470811,0.000923937,0.023573546,0.027380152999999997,0.10630188900000001,-0.034091592999999996,-0.28536443100000003,-0.43951930200000006,0.8841236729999999,1.641405735,-5.288082295,-5.626445381,-4.875713234,-5.518775101,-5.999373917000001,-4.420103844,-6.539617073,-2.159175191,-6.197625637054443,-6.9711809158325195,-6.276997089385986,-6.691406726837158,-7.644561290740967 -3695,3695,L218N,-0.034380883,-0.033071571,-0.10296307199999999,-1.79807484,-2.612333267,-0.073462162,-0.038265399,-0.030496366,0.027045407999999996,-0.09914542,0.033002279,-0.10422192699999999,-0.10170421699999999,-1.879010546,-1.717139134,-2.440474862,-2.7841916710000003,1.076361799,0.690782792,-12.96661017,-12.19876714,-10.3621698,-16.52243047,-15.24110163,-10.50858183,-8.444065399,-4.2233854619999995,-9.201416015625,-11.14574146270752,-7.9585442543029785,-11.327447891235352,-14.333380699157715 -3696,3696,L218Q,-0.036080357,-0.063033365,-0.17492843800000002,-1.738611119,-2.130320525,-0.14672090599999998,-0.064043327,-0.008117387,0.07222351,-0.083389089,-0.04267764,-0.163658453,-0.186198422,-1.660807816,-1.816414421,-2.523302128,-1.737338922,1.1354337970000001,0.727571482,-11.516641400000001,-12.12877222,-10.07949226,-13.47332497,-12.17932923,-9.72228833,-6.399284082,-2.6555147040000002,-7.146573543548584,-9.665434837341309,-8.222694396972656,-9.955602645874023,-11.438735961914062 -3697,3697,L218P,-0.047777103,-0.013548348,-0.008879468,-1.565164754,-2.095105062,-0.095478639,-0.060118954,-0.035435251,-0.013532196000000002,-0.024763436,-0.00233326,-0.016297318999999998,-0.001461616,-1.530617409,-1.599712099,-2.23820976,-1.952000364,1.024458581,0.731841463,-14.18916834,-13.25152785,-13.990549,-16.03448138,-16.88298299,-10.78630045,-8.577109007999999,-4.509438339,-9.419452667236328,-11.483055114746094,-10.751763343811035,-7.09152364730835,-13.503803253173828 -3698,3698,L218S,-0.03369373,-0.009907581,-0.19106020899999998,-1.784374889,-3.0797503139999995,-0.116096276,-0.048959462,-0.018427996999999998,0.00037849,-0.05862287099999999,0.038807708999999996,-0.201259656,-0.18086076199999998,-1.687409599,-1.881340178,-2.819416854,-3.340083773,1.21515909,0.732844825,-10.80714834,-10.73514618,-8.804790703,-13.09964452,-13.14909433,-8.247065994,-6.8253776770000005,-1.702308556,-8.584823608398438,-10.109339714050293,-8.506410598754883,-9.688885688781738,-12.209090232849121 -3699,3699,L218R,-0.032774274,0.007219869,-0.9862792420000001,-2.20290449,-2.751810874,-0.058135224000000006,-0.039314664,-0.026233884,-0.004905424,-0.020281338,0.034721075,-1.021127935,-0.9514305479999999,-2.223170816,-2.182638163,-2.562786382,-2.9408353660000004,0.8003237990000001,0.13086038,-8.827390225,-8.142323524,-6.8725079120000006,-10.28778353,-9.699333244,-9.135002914,-5.410978428,1.0774628309999998,-6.893067836761475,-8.255353927612305,-4.704514503479004,-7.748579025268555,-12.763782501220703 -3700,3700,L218T,0.014576708999999998,0.004411020999999999,-0.006654996,-1.54755897,-2.242838135,-0.132305396,-0.041012009,0.070165426,-0.056035789,0.000589628,0.008232413000000001,-0.029985551000000003,0.01667556,-1.426673574,-1.668444366,-2.445515087,-2.040161183,0.618889537,0.7050145329999999,-8.521758916,-7.709965286,-7.067710114,-9.833602615,-12.13737011,-5.860146454,-6.582300276000001,-2.163665871,-6.971689224243164,-9.507176399230957,-7.789722919464111,-9.279483795166016,-12.418514251708984 -3701,3701,L218W,0.000904237,0.039769528,-0.687777765,-1.865651239,-2.414557624,-0.11449863099999999,-0.029071924,0.030880397999999996,0.028070915,0.046746039,0.032793017,-0.7544871679999999,-0.6210683610000001,-1.764644523,-1.966657954,-2.5022000980000003,-2.326915149,2.105316931,0.987067598,-11.69260705,-10.13171888,-12.73180041,-14.46376572,-9.942488617,-11.19326164,-8.169695392000001,-2.92512573,-10.500419616699219,-12.921486854553223,-9.72107982635498,-11.46925163269043,-13.64278793334961 -3702,3702,L218V,-0.002427662,-0.041385094,-0.004195211,-0.9559772040000001,-2.045548314,-0.09399794,-0.023520269,0.018664945,0.01769726,-0.076660256,-0.006109931,-0.05601664,0.047626219000000004,-0.650411737,-1.261542671,-2.040301576,-2.050795052,1.855945807,1.4132685440000001,-8.662192828,-7.526389,-7.015631217999999,-11.31917018,-10.86951732,-6.580256424,-7.282305222000001,-2.482387337,-7.344189643859863,-8.380078315734863,-8.076725006103516,-7.018588542938232,-9.455948829650879 -3703,3703,L218Y,-0.010062209,0.063228564,-0.49222118600000003,-1.8373467,-2.606993534,-0.066623058,-0.015345484,-0.004778934,-0.001323456,0.026582636,0.099874492,-0.378843765,-0.605598606,-1.804869525,-1.8698238740000002,-2.445515087,-2.76847198,1.500276084,0.761652785,-12.54110254,-9.321149979,-14.70205543,-14.84520763,-12.14179208,-11.69530758,-7.377820467,-2.578954384,-9.01579475402832,-12.399301528930664,-8.947660446166992,-10.035154342651367,-12.926992416381836 -3704,3704,L219A,0.025114333,-0.008984792,-0.018802827,-1.538832679,-1.9655427090000002,-0.036415291,0.02520131,0.025027356,-0.023270697000000003,0.00562387,-0.023593452999999997,-0.077657844,0.040052191,-1.5282194759999999,-1.549445881,-2.270002019,-1.6610833980000002,0.834185235,0.7116021709999999,-8.009758572,-8.677106422,-8.326057837999999,-8.424227821,-6.589509422000001,-8.031891357000001,-5.638754157,-3.088819925,-10.688193321228027,-11.062789916992188,-11.255578994750977,-9.266467094421387,-11.47977066040039 -3705,3705,L219C,-0.006903001,-0.015711658,0.028391857000000003,-1.638408679,-2.7274145780000003,-0.072491812,0.004820308,-0.018626309,0.011960538,-0.01051578,-0.020907535,0.015878928,0.040904786,-1.5850553230000002,-1.691762035,-2.8149545039999997,-2.639874652,0.149696623,0.6805364759999999,-10.54020282,-11.13402138,-10.37099089,-11.03966244,-10.07617941,-10.080160000000001,-8.973277603,-9.972551682,-12.262299537658691,-12.912423133850098,-12.508277893066406,-10.136021614074707,-13.651390075683594 -3706,3706,L219E,0.07766340599999999,0.012207131000000001,0.06259669,-1.638387124,-2.438363166,-0.006254776,0.076460533,0.078866279,0.013357341000000002,-0.020126717,0.044540979,0.001250469,0.123942911,-1.789854421,-1.4869198259999998,-2.292754875,-2.583971457,0.64276054,0.679151458,-11.66728859,-12.15368471,-11.47877463,-12.14192462,-11.10679507,-11.45526392,-9.016060319,-10.11260904,-13.995264053344727,-16.180892944335938,-16.088558197021484,-12.90456485748291,-14.227130889892578 -3707,3707,L219D,0.070535704,0.060995399000000006,0.056442419,-0.9833529320000001,-2.447858334,-0.066191186,0.049082485,0.09198892199999999,0.050061317,0.080793431,0.041197367,-0.004992255,0.11787709199999999,-0.87992501,-1.086780853,-2.711884183,-2.183832484,0.6874554979999999,0.761446911,-12.01517683,-12.16334091,-12.48077892,-12.48298676,-11.48049861,-11.46827892,-9.016060319,-10.11260885,-13.690935134887695,-16.322162628173828,-16.401485443115234,-13.092348098754883,-14.710453033447266 -3708,3708,L219G,0.004724535,0.011219492,-0.255226823,-1.669207766,-2.710439912,-0.006162322,0.007365132,0.002083938,-0.011992107,-0.008269571,0.030708554,-0.332197972,-0.17825567399999998,-1.6363959559999999,-1.702019575,-2.692664476,-2.728215348,1.530181225,0.807469765,-10.81862116,-11.05822324,-11.30454337,-11.34955824,-10.05514713,-10.32563382,-7.064636384,-5.079969338,-13.104228019714355,-13.816131591796875,-13.567180633544922,-12.11410140991211,-13.722850799560547 -3709,3709,L219F,-0.038369486,-0.225249692,0.021873568,-0.00622174,-0.542806621,-0.107124913,-0.06171225,-0.015026722,0.06379011799999999,-0.024716754,-0.42578262899999997,0.019894568,0.023852567,-0.017452874,0.005009395,-0.382050629,-0.703562612,0.6650736620000001,1.473064635,-2.997163843,-3.777477005,-2.770237419,-3.33406266,-2.9047666239999996,-2.199275505,-2.695602487,-2.251337595,-7.3393425941467285,-7.273956775665283,-7.222405433654785,-3.702630043029785,-5.435927391052246 -3710,3710,L219I,0.18619180600000002,-0.300584627,0.077223272,0.050990682999999995,-0.34198399799999996,-0.006621487,0.103516173,0.268867438,-0.007053638,-0.042073852,-0.559095401,0.0008089060000000001,0.153637637,0.020273711,0.081707654,-0.016450487,-0.667517508,1.281800064,2.6320161069999997,-1.586831035,-2.1630085980000002,-1.9536074140000002,-1.644639015,-1.068472404,-1.104427742,-1.783438242,-0.18402698899999997,-4.695772171020508,-6.507208347320557,-5.024245738983154,-3.3098058700561523,-4.331711769104004 -3711,3711,L219H,0.015948308,-0.04401112099999999,0.013208633000000001,-1.613842953,-2.192562432,-0.007528433,0.03084621,0.001050405,7.32e-05,-0.020753857,-0.067268384,-0.040132671,0.066549937,-1.6191581940000002,-1.6085277119999999,-2.3439073969999997,-2.041217466,0.708491084,0.6984635029999999,-10.88346806,-11.94007615,-10.4305128,-10.91085563,-10.43862392,-10.69727181,-9.016060319,-10.1126085,-12.672574043273926,-13.858121871948242,-13.294120788574219,-10.751789093017578,-12.809027671813965 -3712,3712,L219K,-0.000560749,0.036116381,-0.010258716999999999,-1.589377857,-2.040645811,-0.047319220999999995,-0.030744197,0.029622700000000002,0.033994662,0.021968932000000004,0.050263829,-0.031448619,0.010931185,-1.4922041659999998,-1.6865515469999999,-2.421073352,-1.660218269,0.947622538,0.725118061,-11.50395784,-11.92727293,-11.41548264,-11.83239072,-10.68977407,-11.65486882,-9.016060319,-10.11260934,-12.920843124389648,-14.231581687927246,-15.524500846862793,-11.408792495727539,-13.62183666229248 -3713,3713,L219M,-0.055092916,0.09125686300000001,0.004683021,-0.03230548,-0.595117345,-0.052413139000000004,-0.075580596,-0.034605236,0.003610038,0.025390306,0.15712342,0.01034455,-0.0009785080000000001,-0.053000939000000004,-0.011610021000000002,-0.41156672899999996,-0.77866796,1.1186367190000002,1.671303432,-4.106352252,-4.575011856000001,-3.6470669630000003,-5.772195839,-3.147541168,-3.389945435,-5.088416564,-2.674381237,-7.10252046585083,-7.1092610359191895,-6.308584690093994,-5.450434684753418,-6.774129867553711 -3714,3714,L219N,-0.026094242,-0.008409513,0.000884204,-1.480173015,-2.58579938,-0.11456295,-0.02842621,-0.023762274,0.00857715,-0.040091615,0.02327259,-0.09451642199999999,0.096284829,-1.3665915830000002,-1.593754446,-2.693400777,-2.4781979830000003,0.998709805,0.747776584,-11.43184657,-12.04677184,-11.40608025,-11.70255564,-10.77312357,-11.23070152,-9.016060319,-10.11260922,-12.746822357177734,-13.467362403869629,-13.872581481933594,-10.603340148925781,-13.36835765838623 -3715,3715,L219Q,-0.008193556,-0.031420794,0.013768855,-1.5956992069999998,-2.141130018,0.011933808999999998,0.023340042999999998,-0.039727155,0.046714232,0.013327199,-0.076168787,-0.04167621,0.069213919,-1.477364804,-1.7140336090000001,-2.059446503,-2.222813532,0.79896248,0.7181723790000001,-11.29410985,-11.58817986,-11.34909618,-11.81362836,-10.32032532,-11.39931953,-9.016060319,-10.11260922,-12.257901191711426,-12.616497993469238,-13.503628730773926,-9.892942428588867,-12.76990795135498 -3716,3716,L219P,0.013242688,-0.004430684,0.006998325,-0.75809352,-1.8484508530000001,-0.049241707,0.03929659,-0.012811214,-0.017842373999999998,-0.022713587,0.013852218999999999,-0.058634612999999995,0.072631263,-0.631824354,-0.8843626859999999,-2.007276727,-1.689624978,1.803454184,1.407668247,-11.31121702,-11.93466834,-11.253411900000001,-11.67540392,-10.7752403,-10.91736063,-8.415656587,-8.087553656,-11.349596977233887,-13.840733528137207,-12.306178092956543,-10.144612312316895,-12.384476661682129 -3717,3717,L219S,0.043221262,-0.039701381,-0.028592395,-1.4824147769999998,-2.416982134,-0.058391140999999994,0.019563272,0.066879251,0.018400003,-0.006360436,-0.073042325,-0.073626212,0.016441423,-1.382934215,-1.5818953390000001,-2.3311085559999998,-2.502855711,0.668121338,0.710430695,-8.50593278,-9.749859116,-7.973522919,-8.901148376,-7.330169579,-8.574963913,-6.286328004,-4.423684472,-12.229034423828125,-10.873311042785645,-13.281669616699219,-8.951432228088379,-12.202715873718262 -3718,3718,L219R,0.005178914000000001,-0.0056466630000000005,-0.002784307,-1.527060225,-2.207771293,-0.033938708,0.026285284,-0.015927457,-0.008137551,-0.051792030999999995,0.040498705,-0.094909626,0.08934101300000001,-1.540659265,-1.513461184,-2.312990728,-2.102551858,1.003961743,0.728026602,-12.00641646,-12.04749477,-12.39005212,-12.37266973,-10.99386008,-12.22800562,-9.016060319,-10.11260937,-12.717823028564453,-12.77798843383789,-14.953266143798828,-11.790940284729004,-13.032035827636719 -3719,3719,L219T,-0.012405283999999999,-0.005184318,-0.006395438000000001,-1.7066939140000001,-2.383980324,-0.044723892,0.026711078,-0.051521645,-0.015167296,-0.035875131,0.025506496,-0.07840071400000001,0.065609838,-1.6176476030000002,-1.795740224,-2.400388753,-2.367571894,0.797848496,0.7031310340000001,-9.196696576,-9.462819077,-9.274487846,-10.28830209,-7.983264557,-8.974609306,-6.751724866,-5.5816525079999995,-10.282061576843262,-10.788158416748047,-10.655856132507324,-8.294290542602539,-11.00629997253418 -3720,3720,L219W,0.002160145,0.034672722,0.056318645,-1.555166321,-2.493348556,-0.10835258099999999,0.020354569,-0.01603428,0.015167092,-0.001160721,0.07050616400000001,0.030186677000000002,0.08245061299999999,-1.4444931909999998,-1.6658394509999999,-2.146965999,-2.839731112,0.63465847,0.704948481,-10.10031437,-10.6553564,-9.915016143999999,-10.63860181,-9.731742073,-9.560855408,-9.016060319,-10.112609599999999,-11.896833419799805,-11.973807334899902,-11.897991180419922,-12.090906143188477,-10.731478691101074 -3721,3721,L219V,0.028720486,0.006954276,0.003082763,-0.016339212,-0.22787344199999998,0.01576461,0.049244077000000004,0.008196894,0.001345826,-0.034856385,0.048764937,-0.07142853,0.077594056,-0.018436553999999997,-0.014241868999999999,-0.213467587,-0.242279296,1.452381735,2.093390515,-4.535940295,-4.432747101,-5.0720647660000004,-4.378806267,-3.875861496,-4.920221848,-4.52149629,-2.536753793,-6.577071189880371,-7.975317478179932,-6.671717166900635,-5.5612101554870605,-7.506687164306641 -3722,3722,L219Y,0.059062579000000004,-0.289654768,-0.226921464,-2.084155787,-2.240510973,-0.056944697,0.002024261,0.116100896,-0.07191303,0.01834096,-0.597650496,-0.33592936,-0.11791356800000001,-2.011024055,-2.157287518,-2.1159845,-2.365037446,1.395104458,0.70019404,-7.808930042999999,-9.048284973,-7.2053722989999995,-7.732498328999999,-7.603923355,-7.454571259,-7.182748421,-6.757518222000001,-10.885237693786621,-11.44899845123291,-10.175313949584961,-8.349271774291992,-9.53852653503418 -3723,3723,R220A,-0.09285731,0.014737218,-0.037112376,-1.004084057,-2.198580773,-0.013844038000000001,-0.066982252,-0.118732368,-0.055237692000000005,-0.0053727340000000005,0.034847169,-0.040259943,-0.033964809,-0.760250072,-1.247918042,-2.09094906,-2.3062124859999997,1.943661475,1.4172691309999998,-10.02796299,-9.529456985,-8.54125238,-11.87333527,-8.87186245,-11.32390787,-5.208183325,-1.6121659640000001,-11.576953887939453,-9.338089942932129,-8.036812782287598,-10.462562561035156,-11.491125106811523 -3724,3724,R220C,-0.021991661000000003,-0.044092083,-0.33931233200000005,-1.2555514490000002,-1.8430280380000001,-0.024991964,-0.0027799290000000004,-0.041203392,-0.01489921,0.02879867,-0.11698283599999999,-0.24196972100000003,-0.43665494200000005,-1.06501984,-1.4460830569999998,-1.538685226,-2.14737085,3.529698443,2.8088266589999997,-14.10118165,-13.41988519,-12.92780442,-14.92955727,-13.2756386,-15.95302277,-9.277171266,-7.078200245,-12.6337308883667,-10.08175277709961,-9.583961486816406,-10.431602478027344,-11.729455947875977 -3725,3725,R220E,0.051373450999999994,0.07172430099999999,-0.061008012,-1.7368185180000002,-2.4277697430000003,-0.021486,0.056896403,0.045850499,-0.046507304000000006,-0.022321382,0.165769983,-0.146327155,0.024311132000000003,-1.4709675309999999,-2.002669504,-2.240523273,-2.615016212,1.156099235,0.758528581,-12.92887119,-12.8564987,-11.42043869,-14.10168571,-12.88538663,-13.38034622,-7.464895001,-4.200399265,-13.089305877685547,-12.279690742492676,-9.58495044708252,-11.03829288482666,-13.00622844696045 -3726,3726,R220D,0.10495761599999999,0.077611577,-0.238104139,-1.73191135,-2.689181867,-0.018409437,0.125500133,0.08441509800000001,-0.010944162,0.028308392,0.126914761,-0.261883032,-0.21432524600000002,-1.973515823,-1.4903068769999999,-2.839981578,-2.538382155,1.204528733,0.6844142559999999,-14.10282911,-13.35984666,-13.16314949,-14.75838268,-13.64662033,-15.58614641,-8.195634095,-5.1903931530000005,-12.765691757202148,-12.671516418457031,-10.340997695922852,-11.880830764770508,-13.719120025634766 -3727,3727,R220G,0.032107894,0.06948671599999999,0.02790633,-1.430734526,-1.927532395,-0.081976998,0.041578397,0.022637391,-0.050108313,0.023689366,0.115284065,-0.008315852,0.064128512,-1.350300421,-1.51116863,-2.09465673,-1.76040806,2.380394008,1.533726088,-10.78065263,-10.94027393,-9.785020874,-12.03800871,-10.06550986,-11.0744498,-6.224211257,-2.940466789,-11.42882251739502,-9.73552417755127,-7.754985809326172,-9.613090515136719,-11.49800968170166 -3728,3728,R220F,0.004401698,0.039505688,0.044299042000000004,-1.747084841,-2.505385354,-0.010843353,-0.030420885,0.039224281,-0.060000245,0.105202945,-0.026191568999999998,0.004337067,0.084261017,-1.438668815,-2.055500866,-2.606164566,-2.404606141,0.537557446,0.700131142,-14.62434725,-13.50058071,-12.86116742,-14.14083429,-13.24637798,-19.37277585,-9.087505455,-6.670060691000001,-13.31576156616211,-12.439407348632812,-11.86916732788086,-12.526066780090332,-13.225269317626953 -3729,3729,R220I,0.032712336,0.06137694,-0.060326186,-1.622727732,-2.353178169,-0.011966478000000001,0.023220522,0.04220415,-0.041710966,0.012952749,0.109801131,-0.124575115,0.003922744000000001,-1.6467622419999999,-1.598693221,-2.735076747,-1.9712795909999998,0.948502581,0.708796263,-12.60486958,-11.82774434,-10.92513641,-14.18748773,-11.31427025,-14.76970917,-7.3335599060000005,-3.9712676730000003,-11.850605010986328,-11.390833854675293,-10.500788688659668,-11.266225814819336,-12.455826759338379 -3730,3730,R220H,0.009439016,0.029295277999999998,0.02892705,-1.1843293129999999,-1.4760753469999999,-0.085799325,-0.01086206,0.029740091,-0.03464855,0.048042537999999996,0.010548018000000001,0.029431357000000002,0.028422742,-0.879343997,-1.4893146290000001,-1.5221362330000001,-1.43001446,2.789902573,2.197331546,-8.23991129,-8.997309113,-7.65426931,-7.93286705,-7.744955032000001,-8.870155945,-6.470422817,-4.564920165,-9.861262321472168,-9.175307273864746,-7.3949432373046875,-7.325529098510742,-9.211626052856445 -3731,3731,R220K,-0.015958948,0.022408149,-0.001500778,-0.036218533,-1.795858879,-0.09151713800000001,-0.014405971000000002,-0.017511923999999998,-0.001701507,0.064242208,-0.01942591,0.03902542,-0.042026975999999994,0.045237934,-0.117674999,-1.7485126180000001,-1.84320514,0.540058444,1.3041697079999999,-6.765942548,-5.88325724,-6.381748032000001,-7.583916618,-6.957897491000001,-7.022893356,-5.612307782,-1.321613255,-6.205570220947266,-5.23123836517334,-4.702653408050537,-6.678652763366699,-7.06589412689209 -3732,3732,R220M,0.05056911,0.0006833039999999999,-0.011099600000000001,-1.557312971,-2.584173075,0.014297127,0.066382843,0.034755376,0.040326907,0.033201776,-0.031835168,-0.051865448,0.029666248,-1.7192672690000002,-1.395358672,-2.7106717610000004,-2.457674389,0.7249426659999999,0.6876679440000001,-13.69249079,-12.84961121,-12.72874238,-16.00241448,-11.92665916,-14.9550267,-8.613598877000001,-6.503826029,-12.65421199798584,-11.153124809265137,-10.760943412780762,-11.61336898803711,-12.612401008605957 -3733,3733,R220L,-0.003707532,0.02374803,-0.062214075,-1.473826394,-1.5724576069999998,-0.039784775,-0.002244845,-0.005170219,-0.036002499,0.06997297599999999,-0.022476917000000003,-0.077417239,-0.047010910999999996,-1.3399301909999999,-1.607722597,-1.671282744,-1.473632469,3.31043286,2.4695464780000003,-11.1816478,-11.14716043,-9.72966774,-13.23164138,-9.125238434,-12.67453101,-7.123150442999999,-2.884932529,-10.723833084106445,-9.770238876342773,-9.338586807250977,-10.217880249023438,-11.157876014709473 -3734,3734,R220N,0.056449047,0.033723154,-0.008871641,-1.654448986,-2.334290873,-0.046587683,0.077944683,0.03495341,-0.06454536599999999,0.001617618,0.06582869,-0.105505065,0.08776178400000001,-1.789633115,-1.5192648569999998,-2.422015664,-2.2465660819999997,0.9363217690000001,0.6935290120000001,-12.06991081,-11.63068803,-11.71998899,-12.70133691,-11.54882051,-12.74871962,-7.682893109,-4.685203522,-10.89645004272461,-9.806118965148926,-8.430526733398438,-9.830554962158203,-11.494023323059082 -3735,3735,R220Q,-0.010781483,-0.002928433,-0.024666001,-0.837219853,-1.8367785090000002,-0.069753118,-0.037920922999999995,0.016357958,-0.081084822,-0.007694021,0.001837155,-0.066849361,0.017517359,-0.562185964,-1.112253741,-1.860015484,-1.813541534,1.817513216,1.45516832,-8.863474127,-8.119632751000001,-8.528393433,-9.98339225,-8.548515045,-9.137437157,-5.736047791,-3.5562334260000004,-9.801382064819336,-8.686243057250977,-7.4087910652160645,-7.5963134765625,-9.425070762634277 -3736,3736,R220P,-0.00830408,0.054148336,-0.612347998,-1.841706928,-2.0975707619999997,-0.055375802,-0.008306196,-0.008301964,-0.044711684,0.029807155,0.07848951700000001,-0.532583583,-0.6921124129999999,-1.775557694,-1.9078561619999999,-2.105316504,-2.089825019,3.231175122,2.046831322,-10.40492365,-11.47006301,-7.419134483,-10.62681299,-10.66990399,-11.83870377,-5.365955402,-0.753065333,-10.505788803100586,-11.178074836730957,-8.970392227172852,-10.528461456298828,-10.99504566192627 -3737,3737,R220S,-0.044056316,0.04914365,0.043992352,-1.273530005,-1.917546496,-0.009241303000000001,-0.036562852,-0.051549779000000004,-0.034710707,-0.0033023859999999996,0.101589685,0.006487453000000001,0.08149725,-1.074905394,-1.472154615,-2.18319098,-1.6519020119999999,2.124196556,1.424208441,-10.8510185,-11.23494728,-9.291543007000001,-11.6561132,-10.01143958,-12.06104945,-6.705582532999999,-2.754874814,-10.88478946685791,-9.443909645080566,-8.344919204711914,-9.495037078857422,-11.24770450592041 -3738,3738,R220T,-0.050152242,0.046440325,0.049117285,-1.56531545,-2.091349899,0.046932,0.0016972220000000002,-0.102001706,-0.044136774000000004,0.028957266000000002,0.063923383,0.026035172999999998,0.072199396,-1.430936365,-1.699694534,-2.243044458,-1.939655339,0.635994059,0.7067719140000001,-11.29876296,-11.29609029,-8.808989853,-12.74138766,-10.40615898,-13.24118801,-7.220746742,-3.0575098019999998,-11.989291191101074,-10.129470825195312,-8.662973403930664,-10.239813804626465,-11.721205711364746 -3739,3739,R220W,-0.008660303000000001,0.050848317999999997,-0.309149768,-1.8535074409999999,-2.373247326,0.087150357,-0.022652882000000003,0.005332277,-0.020885703000000002,0.002402567,0.099294069,-0.361571476,-0.256728059,-1.833403684,-1.8736111969999998,-2.52377818,-2.222716471,1.4499751719999998,0.743278537,-12.76040882,-12.28045736,-12.01479764,-13.06960883,-12.61656267,-13.82061761,-8.273217281,-5.709740312999999,-11.775341033935547,-12.794586181640625,-10.759675025939941,-11.342413902282715,-11.36038875579834 -3740,3740,R220V,-0.053283579000000005,0.041751306,0.023613831000000002,-1.9471586090000002,-2.383732783,-0.000405249,-0.021952131,-0.084615027,-0.033201837000000005,0.014598845,0.06890376599999999,-0.00326251,0.050490172,-1.679878253,-2.214438964,-2.107011314,-2.660454251,0.728793715,0.690073638,-11.14999872,-10.42345905,-9.321664802999999,-12.83871162,-9.814937241,-13.35122092,-7.104713595,-3.256328392,-12.156473159790039,-10.641183853149414,-9.631305694580078,-11.030220985412598,-12.53748893737793 -3741,3741,R220Y,-0.019912628,-0.0075080830000000005,-0.341932645,-1.75187665,-2.470586539,-0.014996641000000002,-0.009677584,-0.030147671,-0.07621079,0.005078817,-0.020094982,-0.37188369200000004,-0.311981598,-1.896194514,-1.607558785,-2.2855390140000003,-2.655634063,1.526687191,0.748963727,-14.14413983,-14.70015871,-13.54613392,-13.31502305,-13.63152787,-15.527855599999999,-9.262768053,-6.670061201,-11.841625213623047,-12.222972869873047,-10.336080551147461,-11.200653076171875,-12.117242813110352 -3742,3742,S221A,0.013296002,0.021205007,0.012065204,0.050383564000000006,0.015870592,-0.076944536,-0.038312908,0.064904911,0.0077673709999999995,0.021880873,0.02052914,0.008652273,0.015478135,0.100515306,0.000251822,0.025711667,0.0060295159999999995,1.671448915,3.643209181,-1.347885735,-0.768136765,-1.635177101,-0.398970566,-1.405003159,-2.532141083,-2.723929683,1.5354776819999998,-1.0615134239196777,-1.5959467887878418,-1.4211935997009277,-1.8460135459899902,-1.9767013788223267 -3743,3743,S221C,0.018872096,0.044367091,-0.060994547,-0.011062431999999999,-0.009742219,-0.036717413,-0.010593238999999999,0.04833743,-0.031797666,-0.024359346,0.113093527,-0.129301454,0.00731236,0.016745958000000002,-0.038870822,-0.086562894,0.067078456,1.329819675,2.332032883,-8.475028043,-7.9702432860000005,-9.844140617,-7.725577065,-9.467887215,-7.36729203,-7.120383011,-4.502800562,-8.911630630493164,-7.698853492736816,-9.397534370422363,-9.789901733398438,-9.354095458984375 -3744,3744,S221E,-0.084293674,-0.01159765,-0.008828179,-0.0040170729999999995,-0.210797204,-0.08826096,-0.0873062,-0.081281147,0.000692625,-0.035253112,0.012057812,-0.024128174,0.0064718169999999995,0.059884003,-0.067918149,-0.191099347,-0.23049506,1.622205036,2.3701220640000003,-6.1273384779999995,-5.949451447,-4.7322142110000005,-5.735446877,-6.772034812999999,-7.447545044,-5.966824107000001,-2.183214745,-4.91409158706665,-6.291018962860107,-4.064793586730957,-7.32285213470459,-6.4673309326171875 -3745,3745,S221D,0.057000389000000005,-0.052076572,0.026889536000000002,0.085300181,-0.568615666,-0.088083853,0.020151066000000002,0.09384971199999999,0.130017655,0.046892478,-0.151045622,0.02258654,0.031192532000000002,0.061664967,0.108935394,-0.37652401399999996,-0.760707318,0.7419947929999999,1.506499263,-8.225328279,-7.66687574,-8.49714093,-8.146097664,-8.555783196,-8.260743866,-5.254208108,-2.523986524,-5.487860202789307,-7.2345476150512695,-4.679182052612305,-7.2345685958862305,-7.123221397399902 -3746,3746,S221G,0.014584463999999998,0.038798128,0.002388362,0.016935826,-0.267536734,-0.11102721199999999,-0.002535934,0.031704862,0.017457676000000002,-0.018081286999999998,0.095677543,-0.027189299999999996,0.031966023999999996,0.02879191,0.005079741,-0.276685301,-0.25838816600000003,1.143761305,1.803730218,-4.776545912,-5.210262978,-4.436986923,-4.250761993,-4.350130356,-5.634587311000001,-5.082922133,-0.133718807,-4.047018527984619,-4.610589027404785,-4.078042984008789,-4.996264457702637,-4.779699325561523 -3747,3747,S221F,-0.070243544,0.014366965,0.003140533,-0.053616917,-0.342966042,0.001359549,-0.052403838,-0.08808325,0.058813042,-0.118273065,0.147006994,-0.091397097,0.097678162,0.010529148,-0.11776298199999999,-0.475764663,-0.21016742100000002,0.835290152,1.492228805,-9.804486476000001,-10.00811293,-13.14730289,-7.119191322000001,-11.1129268,-7.634898438,-6.3667005020000005,-2.11258775,-8.4769868850708,-8.81574821472168,-7.8316426277160645,-10.468093872070312,-9.098478317260742 -3748,3748,S221I,-0.10987502699999999,0.09160843800000001,0.002263416,-0.023271166,-0.13567684,-0.112812016,-0.127954755,-0.09179529800000001,0.033566992999999996,0.034368902,0.148847973,0.058219267000000005,-0.053692435999999996,0.051290590999999996,-0.09783292199999999,-0.10456505099999999,-0.166788629,1.219628573,2.2200301380000003,-9.98848934,-9.573205688,-13.60964023,-8.773670402999999,-9.496280167,-8.489650215,-7.761173328,-5.00919614,-6.6136794090271,-8.033007621765137,-8.871875762939453,-9.314668655395508,-7.808485507965088 -3749,3749,S221H,-0.04351564,-0.01818806,-0.070630896,-0.047033608,-0.000773092,-0.05471765,-0.071646828,-0.015384451,0.027273431,-0.037840857,0.001464738,-0.073761118,-0.06750067400000001,-0.007665661,-0.086401554,-0.077795603,0.076249419,1.37329066,2.431486283,-10.06415362,-9.153805969,-12.57953767,-8.187497459,-11.50255592,-8.897371094,-6.855869359,-3.240008175,-6.927924156188965,-7.351907730102539,-6.775609016418457,-8.835990905761719,-7.2522292137146 -3750,3750,S221K,0.040610096,0.006747372,-0.076716811,-0.0350234,0.008597157,-0.11000638,0.079181246,0.002038945,-0.109005691,-0.125873709,0.139368452,-0.137313625,-0.016119996,-0.08828756900000001,0.01824077,-0.061371349000000006,0.07856566200000001,1.50874589,2.5125866130000003,-3.516416499,-2.834184685,-5.154495407,-2.5935548930000003,-3.256820854,-3.7430266569999997,-3.272027757,-0.97603211,-4.223941802978516,-6.136259078979492,-4.161801338195801,-6.361083030700684,-4.214273929595947 -3751,3751,S221M,0.031015436,0.047522507,0.084795015,0.060518127000000005,-0.057603585,-0.190118953,0.028357162,0.033673708999999996,0.04745154,-0.022007565,0.117052578,0.016096061000000002,0.153493969,0.079094931,0.041941322,-0.15468965699999998,0.039482487999999996,1.385047423,2.23542946,-9.753989439,-9.062403824,-11.60557642,-8.741639473,-9.460783363,-9.899544113,-6.688578859,-4.211018905,-7.584928512573242,-7.433027267456055,-8.418401718139648,-9.191987991333008,-7.525268077850342 -3752,3752,S221L,-0.05096451,0.034886939,-0.042189721,-0.011901386000000002,-0.16957654600000002,-0.085490355,-0.052174100999999994,-0.049754917999999995,-0.020368203999999997,-0.065489126,0.135263004,-0.073203319,-0.011176122,0.011908588000000001,-0.03571136,-0.23313843399999998,-0.106014657,1.29694063,1.9786941690000002,-8.037123225,-7.937766609,-10.80533835,-7.408326302000001,-7.638717079,-6.395467789,-5.585983425,-2.018267308,-7.183950424194336,-7.588149547576904,-8.128229141235352,-8.980305671691895,-7.470670700073242 -3753,3753,S221N,-0.030863859,-0.041810837999999996,-0.032799748,0.04894479,-0.05864155099999999,-0.163050348,-0.050082992,-0.011644725,-0.06340283599999999,-0.035640356,-0.04798132,-0.038220985,-0.02737851,0.042168038,0.055721542,-0.08682381,-0.030459292000000002,1.1379451520000001,2.259826258,-7.162242485,-7.158728569,-8.213240372000001,-6.522565482999999,-7.867121353,-6.049556647999999,-6.50421611,-3.397661859,-5.714273929595947,-6.5435404777526855,-4.9095540046691895,-7.012870788574219,-5.464333534240723 -3754,3754,S221Q,0.010764663999999998,0.134913907,0.047908309,0.005510136999999999,0.10689935099999999,-0.08665038300000001,0.023684467999999997,-0.00215514,-0.004700571,-0.0371704,0.306998214,0.011794144,0.08402247300000001,0.037135601000000004,-0.026115327999999997,0.002330907,0.211467795,1.187935445,2.7137645339999996,-6.98031357,-7.105926674,-7.153206261,-5.635041885,-7.7253871,-7.282005927999999,-5.349842585,-1.717457855,-5.200098037719727,-6.311951160430908,-5.140101909637451,-7.662361145019531,-5.797963619232178 -3755,3755,S221P,-0.017998835,0.086741931,0.020574503,0.018894151,-0.663132229,-0.119810327,-0.035590001,-0.00040766800000000003,-0.009511951999999999,-0.008074316,0.181558177,0.007962381999999999,0.033186624,0.049044128,-0.011255826000000002,-0.678037496,-0.6482269620000001,0.613258414,1.381434036,-6.390957772999999,-5.563917061000001,-8.476049163999999,-4.840417931,-7.354306587000001,-5.7200981220000005,-5.086052801,-1.533751946,-5.324286937713623,-7.415252685546875,-6.347214221954346,-7.124400615692139,-5.778842926025391 -3756,3756,S221R,-0.029035473,0.050084472000000005,-0.019447645,0.020411612,0.03387427,-0.03652268,-0.03491845,-0.023152495,-0.015429868000000001,-0.025740937999999998,0.125909882,-0.021042041,-0.017853248000000002,0.063618305,-0.022795082,-0.012518433,0.08026697299999999,1.142929939,2.456704713,-7.29006297,-6.411211807000001,-10.06768165,-5.395402907999999,-8.38271785,-6.193300636,-4.77619101,-0.6646182820000001,-5.406286239624023,-7.2826738357543945,-5.519136428833008,-7.289655685424805,-5.50333309173584 -3757,3757,S221T,0.04761746099999999,0.057470325,0.03653916,0.04819617599999999,0.009267263000000001,-0.074329206,0.02556399,0.069670932,0.023198196,0.015027918000000001,0.09991273199999999,-0.005586139,0.078664459,0.07427805700000001,0.022114295,-0.006062896,0.024597421,1.1524789770000001,2.655967199,-4.705452983,-4.372473824,-4.703663322,-3.789113907,-5.135373642,-5.526640221,-5.289556943,-2.457402045,-5.143939018249512,-4.394225597381592,-5.282869338989258,-5.640207767486572,-4.599279880523682 -3758,3758,S221W,-0.064746557,-0.040322853,-0.043348812,-0.013905715,-0.625610278,-0.111746914,-0.023374048999999997,-0.106119065,-0.020368203999999997,-0.050124605999999995,-0.030521100000000002,-0.035614267000000005,-0.051083357,0.05508432,-0.082895749,-0.5381537270000001,-0.7130668290000001,0.72662896,1.434049291,-12.16132428,-10.86875905,-14.86228707,-10.90045983,-12.86628578,-11.30882967,-8.459873712,-5.998991485,-9.640932083129883,-10.797237396240234,-9.323047637939453,-12.2046480178833,-11.253171920776367 -3759,3759,S221V,-0.037365534,0.048904572,0.01075248,-0.011484771999999999,-0.06146742400000001,-0.09011260300000001,-0.081244208,0.006513141,0.011171408,0.0018004529999999998,0.09600869,-0.017843484,0.039348443,0.053341284,-0.076310828,-0.067540105,-0.055394742999999996,1.1988173229999999,2.316014929,-6.8813692,-5.833985687,-10.52621802,-5.939984795,-5.238935944,-6.8677215579999995,-4.452027842,-2.873215645,-5.552356243133545,-5.972084999084473,-6.55086612701416,-7.013982772827148,-5.544779300689697 -3760,3760,S221Y,0.028502233999999998,0.054065074000000005,-0.04306758,-0.00507039,-0.10799013800000001,-0.160906523,0.033340549,0.023663918,-0.040761362,-0.053804132000000005,0.16193428,-0.058701498,-0.027433662,-0.026053127000000002,0.015912347,-0.145153073,-0.07082720299999999,1.329929066,2.153736191,-10.08620422,-9.817915702999999,-13.79009279,-7.678928177,-11.34765538,-7.7964290620000005,-6.178912442000001,-2.381206605,-7.969553470611572,-9.264039993286133,-7.296319007873535,-9.397392272949219,-9.17275619506836 -3761,3761,A222C,-0.016669517,-0.08965373300000001,-0.015116536000000002,-0.08258270200000001,-0.139486071,-0.002048456,0.07240973,-0.10574876400000001,0.016064838,-0.14186067,-0.037446795,-0.000965403,-0.029267669,-0.09082368199999999,-0.074341721,-0.158143286,-0.120828856,1.3879482730000001,2.166400299,-5.915068031000001,-5.051879463,-6.235419556,-6.550109733999999,-6.620855087000001,-5.1170763169999995,-5.496373791,-4.130638746,-7.689075946807861,-8.260501861572266,-8.394492149353027,-7.690946578979492,-7.309131622314453 -3762,3762,A222E,0.077525192,-0.04733885,-0.018074015,-0.002904115,-0.025283249,-0.08411219,0.14957188800000001,0.005478495999999999,0.011570546000000001,-0.004035767,-0.090641932,0.0038741220000000002,-0.040022152000000005,-0.004964739,-0.000843491,-0.017972302,-0.032594196,1.317512686,2.731157623,-3.25373109,-2.708708519,-3.485268822,-2.9577938610000003,-2.9073614119999998,-4.209522835,-2.752842573,-1.4248356130000002,-5.202414035797119,-7.745347499847412,-3.991560220718384,-7.143778324127197,-6.70293664932251 -3763,3763,A222D,0.009232568,-0.044418049,0.06622020299999999,0.017654796,-1.188570578,-0.096227727,0.09345099300000001,-0.074985857,0.021890037,0.012306697,-0.10114279400000001,0.069006666,0.063433739,0.029075077,0.006234514,-1.02824821,-1.348892945,0.544952934,1.336580847,-4.546954218,-3.678366013,-4.278986176,-4.479449806,-4.51753157,-5.780437523,-3.898611523,-0.805515128,-5.021795749664307,-8.467361450195312,-4.639854431152344,-7.133693695068359,-7.497705459594727 -3764,3764,A222G,0.011585791000000002,-0.017558136999999998,0.006071433,-0.018605645,-0.205126728,-0.107007095,0.046599478,-0.023427896,0.030729267,-0.017904846999999998,-0.017211426000000002,0.03992867,-0.027785805,-0.034008354,-0.003202936,-0.19619887100000002,-0.214054584,1.511576925,2.2266338230000002,-3.824290279,-2.862698364,-4.676835037,-3.6444411239999996,-3.653767235,-4.283709633,-2.7518254260000004,1.988226609,-1.2114737033843994,-3.053133726119995,-1.0095651149749756,-1.221787929534912,-2.703643798828125 -3765,3765,A222F,0.128752507,-0.00666986,0.081682797,0.030495897999999997,-0.604300296,-0.061213862,0.17269073899999998,0.08481427400000001,0.070406951,-0.143993677,0.130653957,-0.01864422,0.182009814,-0.004620198,0.065611993,-0.629344174,-0.5792564170000001,0.839728922,1.44451655,-5.349680391000001,-5.967559227000001,-3.699526833,-6.050998459,-5.451745461000001,-5.578571976,-4.547390027,-1.6144639969999999,-7.366462707519531,-9.168802261352539,-7.321427345275879,-7.714158058166504,-7.537705421447754 -3766,3766,A222I,0.009843044,-0.055860865999999995,0.066835569,-0.052945730999999996,-0.127924825,-0.222302012,-0.019505985,0.039192072,-0.011433131000000001,-0.043916227,-0.067805504,0.11336313199999999,0.020308006,-0.11732447800000001,0.011433016,-0.102199902,-0.153649748,1.3996322890000001,2.270579901,-1.159869939,-0.361999245,-1.3234991459999998,-1.533815506,-1.462224159,-1.117811638,-3.866328422,-2.668206369,-6.3416056632995605,-6.6360673904418945,-6.968121528625488,-7.891834735870361,-6.545823097229004 -3767,3767,A222H,0.069385264,0.007654783,0.021255012,0.036850787,-0.080251335,-0.101127496,0.125623744,0.013146783,0.00622198,-0.039392347,0.054701913,-0.035733336,0.078243359,-0.056847338,0.130548912,-0.13557676,-0.024925909,1.416113825,2.236840716,-3.507843648,-1.380369675,-3.190487755,-5.13312175,-3.890944672,-3.9442943880000003,-2.592144486,-1.697351478,-5.131069183349609,-8.421778678894043,-5.379312515258789,-8.037860870361328,-5.468344688415527 -3768,3768,A222K,0.235088397,0.07222701599999999,0.089258401,0.058121448,0.135756478,-0.132984593,0.41995045700000005,0.050226337,0.040576987,0.05394058,0.090513452,0.047231559000000006,0.131285242,0.006749417,0.109493478,0.010036136999999999,0.261476818,1.069398933,2.43860654,-4.448323361,-3.0523050310000004,-3.759271591,-5.185012459,-4.0948066480000005,-6.150221077,-3.5941859289999996,-1.173238727,-5.203887462615967,-6.162301540374756,-4.1348557472229,-7.460072040557861,-5.329005241394043 -3769,3769,A222M,0.0050857559999999994,0.018102366,-0.08541638300000001,-0.071236818,-0.314588866,-0.054420422999999996,0.069435098,-0.059263587,-0.05917305900000001,0.025288317999999997,0.010916414,-0.02184936,-0.148983405,-0.093739966,-0.04873367,-0.080655932,-0.5485218000000001,1.138072556,2.134023299,-5.735192502,-4.006751396,-3.905764908,-8.425750946,-5.4672763060000005,-6.870418953,-4.601691763,-1.5981526869999998,-7.412105083465576,-6.799082279205322,-6.960583209991455,-8.14822006225586,-6.7115302085876465 -3770,3770,A222L,0.032905125,-0.011462805,0.041377807,0.004574363,-1.220598653,-0.127724715,0.064336742,0.001473508,0.037593154,0.00075709,-0.023682698999999998,0.04558834,0.037167274,0.00041224,0.008736485,-1.141003267,-1.300194039,0.760138953,1.34874475,-3.492198415,-1.6061128230000001,-1.567982651,-6.180989342,-4.578330528,-3.5275767289999997,-3.71999773,0.216618074,-6.3102335929870605,-7.238296985626221,-6.288785934448242,-7.08326530456543,-6.056210994720459 -3771,3771,A222N,-0.042167086,-0.04235562,-0.015291484,-0.004257116,-0.165455814,-0.063853172,0.047043826,-0.131377997,-0.162032404,-0.060016013,-0.024695227,-0.058572167,0.0279892,0.039798942000000004,-0.048313173,-0.146827887,-0.18408374,1.33464925,2.175488138,-5.345698087,-4.446358299,-5.880059372000001,-6.279324989,-5.652697975,-4.470049797,-3.9737792389999997,-1.709857225,-5.069986820220947,-7.12443733215332,-4.543061256408691,-7.2442731857299805,-5.171106338500977 -3772,3772,A222Q,-0.071985992,0.05277210400000001,-0.021736684,-0.081044915,-0.035363378,-0.142716184,-0.05416115,-0.089810833,-0.044780495999999996,0.014253018999999999,0.09129118800000001,-0.018454943999999997,-0.025018422999999998,-0.053622743,-0.10846708699999999,-0.14106438599999999,0.07033763,1.214426495,2.065198127,-3.5298346310000004,-2.68050824,-2.628748772,-4.151490685,-3.491928917,-4.6964965439999995,-4.206015428,-0.462552009,-5.205070495605469,-6.386816501617432,-4.154925346374512,-7.51588773727417,-5.20721435546875 -3773,3773,A222P,0.019195523,-0.019155099999999998,0.007502622,-0.0070013340000000006,-0.20669553,-0.085291619,0.050764192,-0.012373146000000002,0.005303771999999999,-0.01280776,-0.02550244,0.023083459,-0.008078216,-0.011911868999999999,-0.002090799,-0.194006923,-0.219384136,1.543956029,2.264664722,-6.196590297999999,-5.672433441,-5.457395241,-5.8073669279999995,-6.823813727999999,-7.221942154,-5.053539579,-1.7113810130000002,-6.091361045837402,-7.594940185546875,-5.677793025970459,-7.41422700881958,-6.948381423950195 -3774,3774,A222S,0.018724452,-0.044909162999999995,-0.00795535,-0.014477048000000001,-0.084670226,-0.070895657,0.096907899,-0.05945899599999999,0.043756915,-0.055259351,-0.034558975,-0.005554094,-0.010356605999999999,-0.039837301,0.010883206000000001,-0.106603945,-0.062736506,1.287981567,2.198020287,-0.7343780459999999,-0.184530312,-1.564515717,-0.9189556809999999,-0.287408966,-0.716479553,-1.386100088,-1.08074493,-4.4364495277404785,-4.74067497253418,-3.8176662921905518,-4.801131725311279,-4.487364768981934 -3775,3775,A222R,0.092091915,0.009459268,0.000608778,0.0077223380000000005,0.012398433,-0.100592322,0.09865269300000001,0.085531137,0.01527745,-0.045907120999999995,0.06482565700000001,-0.045509694,0.046727249000000005,-0.046906362,0.062351038,-0.046128088,0.070924953,1.303740555,2.449109932,-4.010011943,-2.33474852,-4.46643689,-4.661193237,-4.7642013169999995,-3.823479752,-2.7573088489999997,-1.17503294,-5.141017913818359,-6.879477500915527,-4.466969013214111,-7.077035903930664,-5.161637306213379 -3776,3776,A222T,0.0033600059999999996,0.01135333,-0.008364168,0.008498593,-0.052968743,-0.109575344,0.020858174,-0.014138163,-0.017187222,-0.020878871,0.043585531,0.001151956,-0.017880292,0.020173716,-0.003176531,-0.040979728,-0.064957758,1.2333858640000002,2.446336745,-1.794014113,-1.9327110369999998,-1.9368624190000001,-1.7860134509999999,-1.9385584869999999,-1.375925171,-3.1734086660000003,-2.51385407,-5.695765972137451,-4.053277492523193,-4.735060214996338,-6.37794303894043,-4.9144206047058105 -3777,3777,A222W,-0.003783173,-0.031795399,0.01776065,-0.001784315,-1.279806225,-0.09870786,-0.011950693,0.004384348,0.056525603,-0.102879388,0.03928859,-0.014093895,0.049615195,-0.062331502000000004,0.058762873,-1.270249661,-1.289362788,0.923678207,1.3597565440000001,-8.583818443,-6.975166878,-8.538917351,-9.055075874,-8.232452126,-10.11747999,-5.913620087000001,-4.060091644,-8.2005615234375,-11.63978385925293,-8.008460998535156,-9.549838066101074,-9.068902969360352 -3778,3778,A222V,0.018111133999999997,-0.008535191999999999,-0.020136526999999998,-0.057140678,-0.038754442,-0.083972576,0.040061649,-0.003839381,-0.019038025,0.018670547,-0.035740931000000004,0.036948102999999996,-0.077221157,-0.081226168,-0.033055187,0.025505051,-0.103013935,1.255597429,2.862599988,2.269701924,2.360969681,2.282687073,1.8649062809999999,2.4394513019999997,2.400495285,-0.069132053,-1.175615759,-5.122751712799072,-4.138936996459961,-5.264304161071777,-5.927412986755371,-4.546076774597168 -3779,3779,A222Y,0.162187481,-0.022068089,0.010535828,-0.013866402,-0.274795451,-0.176021625,0.218252273,0.106122688,0.024970864,-0.09010510000000001,0.045968922,-0.055390508,0.076462164,-0.040181374,0.01244857,-0.416263424,-0.133327477,1.7119830169999999,2.076329274,-4.919914835,-3.1250786589999997,-2.9464520110000003,-6.278086662000001,-5.564075462000001,-6.6858813779999995,-4.163625201,-0.20548800600000003,-6.400249481201172,-9.909770011901855,-6.453658103942871,-7.556193828582764,-7.239569664001465 -3780,3780,L223A,-0.01622418,0.01503737,0.0007258710000000001,0.020766215,-0.244925714,0.0186056,-0.047784640999999996,0.015336282,0.011096528,0.00955909,0.02051565,0.003388053,-0.001936311,0.007964207,0.033568222,-0.253065375,-0.236786052,1.668595501,2.259885159,-7.905869034,-7.419652771,-7.473060516,-8.629637367,-7.5664908220000004,-8.440503693,-4.398811554,-2.897793467,-5.807528495788574,-7.342067241668701,-5.518072128295898,-6.714959144592285,-6.612483978271484 -3781,3781,L223C,0.011245554,-0.024437723999999997,-0.052557504000000005,-0.025110556000000003,-0.05901323,0.076046747,0.008189446999999999,0.014301661,0.025155486,-0.11358167599999999,0.064706228,-0.121881357,0.016766349,-0.130483171,0.08026206,-0.142579074,0.024552615,1.48279952,2.211063669,-10.74498275,-10.74852754,-10.70893054,-10.69626759,-10.45178165,-11.11940641,-8.669689527000001,-7.3263794120000005,-8.454301834106445,-9.868232727050781,-8.3799409866333,-11.053628921508789,-10.364904403686523 -3782,3782,L223E,-0.09717524,-0.006813721,-0.89948057,-2.3642507530000003,-2.5012192069999997,0.025868121,-0.11252812400000001,-0.081822356,-0.148741651,-0.08975699300000001,0.076129552,-0.757536795,-1.041424345,-1.919320589,-2.8091809160000003,-2.618152041,-2.384286373,2.063227267,0.8942876129999999,-11.62764005,-10.51035503,-11.20667743,-12.37671854,-11.04185017,-13.00259906,-8.674282246,-7.3263794120000005,-9.093297958374023,-12.915105819702148,-10.823304176330566,-12.338540077209473,-11.453389167785645 -3783,3783,L223D,0.021922375,-0.17191759899999998,-1.346041808,-2.2176567780000003,-2.442670862,0.000637861,0.008065714,0.035779035,-0.096910013,-0.075398843,-0.268436355,-1.306744479,-1.385339136,-2.2167163,-2.218597255,-2.614517756,-2.2708239669999997,0.94060404,0.096316325,-12.059419,-11.00098691,-12.27431371,-12.92290222,-10.75431664,-13.344575500000001,-8.293958587,-6.935782681,-10.163276672363281,-13.96219539642334,-11.699806213378906,-13.758880615234375,-13.096691131591797 -3784,3784,L223G,-0.003895253,-0.002914425,0.02203797,-1.455733325,-2.276690172,0.073134148,-0.032843647000000004,0.025053142,0.029963222999999997,-0.052279198,0.046450349,0.02910497,0.01497097,-1.362397224,-1.549069425,-2.429205461,-2.1241748819999997,0.622004561,0.7097921140000001,-12.02632829,-11.49228792,-11.76791464,-13.01556802,-11.40158453,-12.45428636,-8.696329311,-7.96929821,-9.016633987426758,-11.485466957092285,-8.988730430603027,-12.187748908996582,-10.41649055480957 -3785,3785,L223F,-0.024977389,-0.002282364,-0.043612912999999996,-0.358286469,-1.850101859,-0.15845328,-0.075456522,0.025501745,0.202104691,0.043582285,-0.048147012,-0.10432428099999999,0.017098456,-0.24837930800000002,-0.46819363,-2.044120773,-1.656082944,1.3207584079999999,1.325351849,-4.8695852219999995,-6.0329092179999995,-6.314973579,-3.9716454160000003,-4.072522347,-3.955875549,-5.004782496,-1.803275865,-6.145181655883789,-6.4078826904296875,-7.660103797912598,-8.035761833190918,-6.861302375793457 -3786,3786,L223I,0.057002232,0.10078527400000001,0.090042963,0.047262776,0.039474143999999996,0.050420747,0.036854142,0.077150321,-0.079181246,0.040202545,0.16136800199999998,0.082627676,0.097458249,-0.058634451,0.15316000300000002,-0.008086394,0.087034681,1.3061426740000002,2.5487605330000003,-4.430108545,-4.33567762,-4.255954102,-5.657927521,-3.5620250089999996,-4.338958473,-4.195036769,-1.9215919119999998,-5.217960357666016,-5.389880657196045,-5.096380233764648,-6.63331413269043,-5.263627052307129 -3787,3787,L223H,-0.008521296,-0.026784217000000003,-0.148113904,-1.7012661169999999,-2.545721245,0.023673537999999997,0.015602982,-0.032645574,-0.071315413,0.0009862319999999999,-0.054554665999999995,-0.128015415,-0.168212392,-1.61042476,-1.792107474,-2.3440183180000003,-2.7474241719999997,1.002539858,0.7181881729999999,-10.81228895,-10.78739301,-10.48500703,-11.43800291,-9.549676071,-11.80136574,-7.896500983999999,-6.176094325,-9.182456016540527,-12.374168395996094,-11.215675354003906,-12.812749862670898,-11.522339820861816 -3788,3788,L223K,-0.047470387,0.099646223,0.0393871,-0.013767563,-1.6884486630000002,-0.045375349,0.005877123000000001,-0.10081789699999999,0.057991947,0.101311422,0.09798102300000001,-0.012626478,0.09140067800000001,-0.08748448,0.059949355,-1.641633136,-1.73526419,0.569519494,1.3087406240000001,-11.77766974,-11.59719617,-11.98750078,-12.00763389,-10.37262052,-12.92339734,-8.037370424,-7.065231075,-9.085705757141113,-12.698831558227539,-10.015666007995605,-11.346790313720703,-11.36951732635498 -3789,3789,L223M,0.021106207999999998,0.11616370300000001,0.122654043,-0.013270968000000001,0.006047271999999999,-0.10643216900000001,0.014021532,0.028190884,-0.029963222999999997,0.080504722,0.151822684,0.127824425,0.117483661,-0.020595408,-0.005946526999999999,0.017331706000000002,-0.0052371629999999995,1.006743881,2.549018873,-4.7081482569999995,-5.997968605,-4.654316017,-3.8438911510000002,-4.413504776,-4.631060738,-3.786231373,-2.83668985,-5.875171661376953,-5.880784034729004,-6.450450897216797,-5.350045680999756,-5.657290935516357 -3790,3790,L223N,0.022667768999999997,-0.061991581,0.030404971,-1.431332535,-1.938482333,0.034348286,0.000300097,0.04503544,0.039152123999999996,0.033203177,-0.157186338,0.022190843,0.038619099,-1.5805020330000001,-1.282163036,-1.978303488,-1.8986611780000002,0.9768368629999999,0.709803886,-11.5227623,-11.12206615,-10.85744679,-12.19336495,-10.56183924,-12.87909437,-8.010345323,-6.255310565,-9.427202224731445,-12.085103988647461,-10.116357803344727,-12.469490051269531,-11.858789443969727 -3791,3791,L223Q,-0.0255447,0.067104691,0.029605576,-0.71343107,-1.936262751,0.154440689,0.070132223,-0.12122162199999999,0.10011515300000001,-0.008933799999999999,0.14314318199999998,-0.02077823,0.079989382,-0.266108075,-1.160754065,-2.182423471,-1.690102031,1.2690968440000001,1.303578407,-10.27065863,-9.35040255,-9.963642426,-11.36048344,-8.922516006,-11.75624871,-7.442353359,-5.812606262999999,-7.491145610809326,-10.854854583740234,-9.543564796447754,-11.122163772583008,-9.698431968688965 -3792,3792,L223P,-0.015115276,0.013079278,-0.566095238,-1.8292151680000002,-2.182385851,0.005690359,-0.037197308,0.006966756,0.019878148,-0.021559041,0.047717597,-0.451164165,-0.681026311,-1.8801196869999999,-1.7783106480000002,-2.446325573,-1.918446129,1.637591424,0.778482474,-11.71129259,-11.63045922,-11.37951077,-12.74659602,-10.96383489,-11.83606207,-9.03275832,-8.129810363999999,-6.658693790435791,-10.828227043151855,-8.803025245666504,-11.207927703857422,-8.581347465515137 -3793,3793,L223S,-0.03489905,-0.007726068000000001,0.02858973,0.035860624,-1.648996795,0.037198629,-0.033105354,-0.036692745,0.042860252,-0.038710074,0.023257939,-0.010300126,0.067479585,0.032698836,0.039022412,-1.5654185390000002,-1.732575051,0.5943539210000001,1.312231164,-9.821718893,-9.656863091,-8.981269913,-10.79818472,-9.346191681,-10.32608507,-7.0455155629999995,-5.676442226,-8.101303100585938,-9.843864440917969,-8.093343734741211,-9.812812805175781,-9.09253215789795 -3794,3794,L223R,0.003223101,-0.0027083420000000003,0.018615603999999997,-0.11871141800000001,-1.7008867980000002,-0.010231094,-0.01815188,0.024598082,0.0030888779999999998,-0.02276727,0.017350587,-0.015271156000000001,0.052502362999999996,-0.064248087,-0.17317474800000002,-1.899498092,-1.5022755030000001,0.9205724679999999,1.310891641,-10.64141882,-9.78075544,-10.12378861,-11.76364992,-9.337649635,-12.2012505,-7.744141443999999,-6.138711878,-9.2488431930542,-12.471294403076172,-11.324247360229492,-11.390000343322754,-11.699060440063477 -3795,3795,L223T,0.029845299,0.060832322,0.028537463,0.047910582,0.004756221,0.033113624,-0.0029601109999999996,0.062650708,-0.033471482999999996,0.032979594,0.088685049,0.030050612999999997,0.027024312,0.026472345,0.06934881799999999,-0.040222142999999995,0.049734584000000005,1.462413316,2.7457175389999997,-7.985387666,-8.331459152,-7.451654381,-8.406871681,-7.558410065,-8.178543053,-5.16574992,-3.914584847,-7.101167678833008,-7.281496047973633,-6.158815860748291,-7.524407386779785,-7.626338958740234 -3796,3796,L223W,-0.063666269,0.035789054,-0.053210089,-1.911610452,-2.592646951,0.059376444,-0.06622663599999999,-0.061105901,0.012774288,0.037347805,0.034230302000000004,-0.036220915,-0.070199263,-1.4721625580000002,-2.351058346,-2.414032058,-2.771261843,0.7628318390000001,0.7129528359999999,-9.260689902000001,-9.210002907,-9.44861528,-9.289189056,-8.190283142,-10.16535912,-7.534111542000001,-5.249384518,-9.262807846069336,-11.44525146484375,-10.512125015258789,-12.430928230285645,-10.925479888916016 -3797,3797,L223V,0.008292021,0.043944047,0.098212225,0.064780038,0.023457895,0.02904686,-0.025547663999999998,0.042131706,0.015794267,0.008706848,0.079181246,0.076890746,0.119533704,0.072191301,0.057368775,-0.020315368,0.067231158,1.198314174,2.605887215,-3.9200504819999997,-4.06213221,-3.8620307769999997,-4.690224831,-2.775757729,-4.210106865,-3.920741057,-1.195345552,-4.7586445808410645,-4.351491928100586,-3.379481315612793,-4.598352432250977,-4.169873237609863 -3798,3798,L223Y,-0.008152962,0.039692702999999996,-0.192914747,-1.9015007169999998,-2.1265148,-0.008984502,-0.048289795999999996,0.031983872999999996,0.09247084800000001,-0.060793297,0.14017870300000002,-0.216474261,-0.169355232,-1.4274760780000002,-2.375525355,-2.302398788,-1.950630812,2.305009211,1.378185901,-9.825856645,-10.82243559,-10.91263068,-9.708652855,-8.210140732000001,-9.475423362999999,-7.628486028999999,-5.773600201,-8.767766952514648,-10.39626693725586,-9.86999225616455,-11.310602188110352,-9.797262191772461 -3799,3799,P224A,-0.043017932,-0.001777951,-0.036393722,-0.142841371,-1.655145079,-0.026180387000000003,-0.012111798,-0.073924066,-0.025847882000000003,0.018405448,-0.021961348999999998,-0.042945743,-0.029841701,-0.035188712000000004,-0.250494029,-1.800008258,-1.5102818999999998,0.76686957,1.309204888,-6.756226282,-6.725311134,-7.805786743,-5.776037682,-6.4671285020000004,-7.006867347999999,-6.647958967,-3.76872266,-7.5008392333984375,-7.422304153442383,-8.384504318237305,-8.592985153198242,-7.921390533447266 -3800,3800,P224C,-0.011596533999999999,0.027544647000000002,0.038411022,-0.8779894709999999,-2.236007119,-0.02648039,0.0056471180000000004,-0.028840186,-0.035634707,-0.004454533,0.059543827,0.09496324099999999,-0.018141198,-0.377564445,-1.3784144969999998,-1.962130348,-2.50988389,1.460913057,1.353243587,-10.43475911,-9.647742103999999,-11.74862837,-9.393007277999999,-9.591370384,-11.79304742,-9.077983613999999,-7.186463626,-11.90461254119873,-12.885846138000488,-13.634202003479004,-13.63847827911377,-14.901063919067383 -3801,3801,P224E,-0.035172761000000004,0.046367644000000006,-0.000937916,-0.029731004,-1.914921366,-0.030517181,-0.059532836,-0.010812686,-0.072918568,0.0053218219999999995,0.087413466,-0.07586155,0.073985719,-0.03983953,-0.019622478,-1.664510421,-2.165332311,0.572917774,1.3073025440000001,-7.576746555,-7.556325745,-8.100586853,-6.54115641,-6.934353729,-8.751310036,-6.420307827999999,-3.9775846710000002,-8.050362586975098,-7.786873817443848,-8.620960235595703,-10.498237609863281,-9.797518730163574 -3802,3802,P224D,-0.033585864,-0.026019976,-0.014224496000000001,0.005120009,-2.002474635,-0.000570368,-0.037950318,-0.029221409,0.034125862,-0.02648143,-0.025558521,-0.02508796,-0.003361032,-0.037677512,0.047917529,-1.6369666719999998,-2.367982598,0.790422107,1.317627204,-7.140060559,-7.3235326689999996,-8.346831421000001,-6.161024925,-5.875889992,-7.9930237879999995,-6.013145999,-3.5958751089999996,-8.038352012634277,-7.44931173324585,-8.40363597869873,-10.574556350708008,-9.492459297180176 -3803,3803,P224G,-0.012840932,0.056897012000000004,0.011608398,-0.01224639,-1.271180378,0.041937008,0.010892192,-0.036574055,-0.017412843,0.012490652,0.10130337199999999,-0.004107239,0.027324035,0.01273982,-0.037232599,-1.171968673,-1.370392083,0.650722525,1.336324529,-7.536133981,-6.84745649,-8.935062103,-6.840902092,-6.608627396,-8.448621826,-6.624518817999999,-2.992341218,-7.966106414794922,-7.980132102966309,-7.318642616271973,-9.323896408081055,-8.590655326843262 -3804,3804,P224F,0.013097485,-0.0036308259999999998,-0.09396750400000001,-1.969081501,-2.3177489,-0.081460861,0.027289499,-0.001094529,-0.007266823,-0.069147843,0.06188619099999999,-0.164749954,-0.023185052999999997,-1.815828763,-2.122334239,-2.3359366759999998,-2.299561123,1.130635711,0.70552332,-12.10072019,-10.91148515,-13.62875553,-10.72770535,-10.48105875,-14.75459618,-10.51650051,-10.289760800000002,-11.491202354431152,-12.75879192352295,-13.456659317016602,-13.93591022491455,-13.59200668334961 -3805,3805,P224I,-0.10203846300000001,-0.019671977,-0.13338539900000002,-1.8856398730000001,-2.345231646,-0.003216405,-0.100328279,-0.103748646,-0.19836200399999998,-0.022680141,-0.016663813,-0.155630574,-0.11114022400000001,-1.40689337,-2.364386375,-2.449880029,-2.240583263,1.036205686,0.747084567,-11.18310001,-9.606468536,-12.60415779,-9.130787895,-10.73356805,-13.84051776,-8.995547511,-6.918983342000001,-10.256329536437988,-11.813379287719727,-12.630281448364258,-12.54133129119873,-12.475268363952637 -3806,3806,P224H,-0.079697336,-0.012347118999999998,0.017517412,-0.042706376,-1.47636862,0.007711568,-0.089324902,-0.070069769,-0.014445408,0.02912063,-0.053814867,0.01734668,0.017688144,0.035114513,-0.12052726400000001,-1.552715024,-1.400022215,0.384268978,1.304825418,-8.705838692999999,-7.7758074420000005,-10.26796344,-7.465959152000001,-7.150994904,-10.86846853,-7.567734486,-5.410661625,-9.987017631530762,-9.153324127197266,-10.81158447265625,-11.775867462158203,-11.101719856262207 -3807,3807,P224K,-0.069300817,0.161145901,0.074943041,-0.030139985,-0.676098286,0.06871405900000001,-0.10624941,-0.032352223,0.248796027,0.012081965,0.310209836,0.064522814,0.08536326699999999,-0.136602817,0.076322848,-0.909967944,-0.44222862700000004,1.432759724,1.5922158469999999,-8.160721033,-7.514103317000001,-9.183115562000001,-7.109516212000001,-6.867062675,-10.1298074,-7.33171222,-5.096049949,-8.5569486618042,-8.806138038635254,-7.761933326721191,-10.255916595458984,-9.890921592712402 -3808,3808,P224M,0.035407308,0.021170956,0.051235987999999996,-1.051878651,-1.9145604109999999,-0.175249005,0.037586829,0.033227786,-0.11918075800000001,0.021665583,0.020676328,-0.040327927,0.142799903,-0.706129993,-1.3976273080000001,-1.953236634,-1.8758841880000001,1.9205537190000002,1.45360928,-10.10780444,-9.107720955,-11.53885885,-8.871430885,-9.186659477000001,-11.83435202,-8.599491297,-6.4425002220000005,-11.236907958984375,-12.16901969909668,-13.134504318237305,-12.76694393157959,-12.923067092895508 -3809,3809,P224L,-0.05968981,0.000158413,-0.033260264,-0.911043918,-1.96066277,-0.024097264,-0.049401175,-0.069978444,-0.031450362999999995,-0.013925393000000001,0.014242218000000001,-0.044916192,-0.021604335,-0.437049656,-1.38503818,-1.8149924309999999,-2.106333109,1.638867475,1.414121074,-8.515475665,-7.4973025820000005,-10.21889217,-6.914930152999999,-7.30037307,-10.64588035,-7.089378791000001,-4.538880852,-8.81749439239502,-9.826238632202148,-11.591647148132324,-11.168561935424805,-10.57159423828125 -3810,3810,P224N,-0.056307478,0.13864996300000001,-0.048755344000000006,0.07126316,-1.7892447669999998,-0.023253196,-0.08125882200000001,-0.031356134,0.107466874,0.14833061,0.128969315,0.080046375,-0.17755706300000001,0.157389673,-0.014863353000000001,-1.7212875580000002,-1.857201975,0.5480635939999999,1.3051956470000001,-8.203406853999999,-7.881507881,-9.584591934,-7.352781403,-6.6924887239999995,-9.50566433,-7.319715297999999,-4.715187857,-9.333056449890137,-8.616081237792969,-9.33847427368164,-11.045970916748047,-10.321930885314941 -3811,3811,P224Q,-0.13977319900000001,-0.002776924,-0.061100645,-0.023895898999999998,-1.537817744,0.07483943900000001,-0.104804169,-0.174742229,-0.052233969000000005,-0.005292130999999999,-0.000261716,-0.06535114,-0.05685015,0.11969716300000001,-0.167488961,-1.445081146,-1.630554342,0.590954057,1.317453745,-8.002327081,-7.353986671,-9.033731208999999,-6.938495041,-7.300184135,-9.38523835,-7.5139940979999995,-4.853308932,-8.469890594482422,-8.246565818786621,-9.096806526184082,-10.240480422973633,-10.062360763549805 -3812,3812,P224S,-0.008349018,0.024780352999999998,0.015201058,0.005914849,-1.439181992,-0.012389198999999998,-0.009926373,-0.0067716619999999995,-0.011102828,0.030487623999999998,0.019073081000000002,-0.016481808,0.046883924,0.024361942999999997,-0.012532245,-1.3842772380000001,-1.494086746,0.7774842129999999,1.334834136,-6.353520972999999,-5.875726967,-7.35468499,-6.175396217,-5.6576259989999995,-6.704170692000001,-5.83230788,-3.51359045,-7.7789201736450195,-7.096899032592773,-8.017000198364258,-9.137590408325195,-8.207406044006348 -3813,3813,P224R,-0.02755549,0.035047398,-0.012817569,-0.024783169,-1.512772675,0.028531857999999997,-0.012363096,-0.042747883,0.031283659,-0.000654856,0.070749651,-0.062249381,0.036614243,-0.008291128,-0.041275209,-1.538553041,-1.486992308,0.670212756,1.318099578,-7.909425864,-7.068386932,-9.649589073,-6.466253876000001,-7.317275787000001,-9.04562365,-6.256958472000001,-4.2432981,-9.543941497802734,-9.064411163330078,-9.458612442016602,-11.150886535644531,-10.768284797668457 -3814,3814,P224T,-0.025098662999999997,-0.009297145,-0.015234195,-0.019709311,-1.37993249,0.0011543060000000001,-0.031481578999999996,-0.018715746000000002,-0.050878915,-0.05394096,0.035346671,-0.013345107,-0.017123283,0.014791453999999999,-0.054210075,-1.526045945,-1.233819035,0.6576556020000001,1.31723811,-7.954760509,-7.21993235,-9.120237213,-7.1270816120000005,-7.6873781889999995,-8.61917318,-7.496268219,-4.503390371,-8.70114803314209,-8.361471176147461,-8.69257926940918,-10.13388442993164,-9.587778091430664 -3815,3815,P224W,0.15532373800000002,0.104441202,-0.314811937,-1.189150345,-1.887302746,-0.135060882,0.22880711,0.081840366,-0.028752872999999998,-0.18138339,0.390265794,-0.44749688200000004,-0.18212699100000002,-1.754277005,-0.624023685,-2.399323655,-1.375281837,1.735409644,0.8382576209999999,-10.71430771,-9.152137413,-12.33322221,-9.429019843999999,-9.661503189,-12.99565588,-9.116961557,-6.903278074,-13.334504127502441,-14.228185653686523,-14.508326530456543,-15.754890441894531,-15.939950942993164 -3816,3816,P224V,-0.038828877000000005,-0.007651876,-0.029235933999999998,-1.322304502,-2.5054752909999998,0.027574585,-0.019703729,-0.057954025,-0.009280475,-0.050293669000000006,0.034989917999999995,-0.029579841000000003,-0.028892027,-1.039446535,-1.605162468,-2.22856123,-2.782389352,0.8134078440000001,0.7601475320000001,-9.825943521000001,-8.655365234,-11.46084232,-7.761640915,-9.751205711,-11.50066342,-8.178654647,-5.507813129,-9.266992568969727,-10.526898384094238,-11.43278980255127,-11.23334789276123,-11.02777099609375 -3817,3817,P224Y,-0.10605901,0.016535638999999998,-0.013409187,-1.6987293330000002,-2.260381099,-0.001388359,-0.099498752,-0.112619267,0.068059863,-0.05165239,0.084723668,-0.08731696,0.06049858599999999,-0.955539224,-2.4419194419999997,-2.202645866,-2.318116331,2.052593775,1.4004838769999999,-10.73663522,-9.245885048,-12.36798798,-9.373981468,-9.165609955,-13.52971162,-9.093148246,-6.903278112000001,-11.559555053710938,-12.53934097290039,-13.000828742980957,-13.961349487304688,-14.244775772094727 -3818,3818,A225C,0.017269176,-0.026362137999999997,0.002254677,0.011390376,-0.100035783,0.005161288,-0.046757596,0.08129594799999999,0.111255729,-0.043864969000000004,-0.008859305999999999,-0.031088152,0.035597505,-0.0031266420000000002,0.025907392999999997,-0.107525935,-0.092545631,1.41491968,2.307297164,-6.6443769360000005,-6.5785547410000005,-6.79270018,-6.443468482999999,-6.904498505,-6.502662773,-7.231797202999999,-6.501824432,-10.084114074707031,-11.702178955078125,-11.094669342041016,-10.898368835449219,-11.486741065979004 -3819,3819,A225E,-0.123036721,-0.105161037,-0.046598694,-0.019734283999999998,-0.084060168,-0.012837237,-0.193889195,-0.052184246,0.08748605699999999,-0.09562286699999999,-0.114699207,-0.018654179,-0.074543209,0.07010363,-0.109572197,-0.052449372,-0.115670964,1.3566037219999998,2.615959336,-0.9488170229999999,-0.556728256,-0.19142511,-1.4780965190000002,-1.952691025,-0.565144203,-1.099744142,-0.432427558,-2.14980149269104,-3.4305849075317383,-2.5523734092712402,-3.833893299102783,-3.3559272289276123 -3820,3820,A225D,0.052145342000000004,0.061116697000000005,0.026594272999999998,0.020426556000000002,-0.024881322,0.014741518,0.036573576000000003,0.067717107,0.05844381,0.036707661,0.085525732,0.031345173999999996,0.021843372000000003,0.030323987,0.010529123999999999,-0.061205982,0.011443338,1.309040408,2.490008569,-1.660967979,-1.670252892,-0.868933975,-2.081638298,-2.592804848,-1.091209885,-2.382661916,-0.35516354299999997,-2.7939906120300293,-4.199550628662109,-3.266479253768921,-5.240575790405273,-3.8264644145965576 -3821,3821,A225G,-0.021080223999999998,-0.032623571000000004,-0.013176321999999999,-0.01588891,-0.082549558,0.007140723000000001,-0.057071062,0.014910615,-0.007557273000000001,-0.003507058,-0.061740084,-0.022179235,-0.004173409,-0.020063097,-0.011714723,-0.05297309,-0.112126025,1.375386059,2.490627003,-2.5715133619999997,-3.1652006839999998,-2.230569252,-2.291406479,-3.173623825,-1.996766571,-3.178321663,-1.986585295,-5.297670841217041,-6.237884044647217,-5.198602199554443,-6.569439888000488,-5.681063652038574 -3822,3822,A225F,0.012164017,-0.017228241000000002,-0.067781864,-0.008420174,-0.16448658800000002,-0.066225441,-0.046034298,0.070362332,-0.052393029,0.025349682000000002,-0.059806162999999996,-0.071132793,-0.064430935,-0.040317887999999996,0.02347754,-0.115565111,-0.213408065,1.363340166,2.209659556,-6.077455562999999,-6.0910245739999995,-5.93890033,-5.91553968,-6.929479507000001,-5.512333725,-5.29973337,-4.417117756000001,-8.582014083862305,-9.937265396118164,-9.221724510192871,-11.049203872680664,-9.312650680541992 -3823,3823,A225I,-0.008786755,-0.086589304,-0.01092792,0.06226434,-0.067274635,0.00110001,-0.113523468,0.095949959,-0.054486019000000004,-0.051096029,-0.12208257800000001,-0.023708142999999997,0.0018523029999999998,-0.025101922000000002,0.149630601,-0.12661232,-0.00793695,1.31588563,2.2093289130000002,-4.6851571430000005,-3.9923542710000004,-4.53245137,-4.8019976810000005,-5.232195267,-4.866787125,-4.746965367,-4.119208708,-6.729598522186279,-8.618512153625488,-7.979719638824463,-7.948516368865967,-7.70243501663208 -3824,3824,A225H,0.029723127999999998,-0.075093041,0.016963599,0.0011125689999999999,-0.076997698,-0.001974937,-0.001110047,0.060556302,-0.00675396,-0.08057388900000001,-0.069612193,0.004872611,0.029054586,-0.030572701,0.032797837999999996,-0.041428285,-0.112567111,1.311469748,2.424453589,-4.211403418,-4.571279221,-4.181038971,-3.733018448,-5.071993492,-3.4996869580000003,-4.0473252980000005,-3.220453862,-5.966635227203369,-6.935834884643555,-6.796431064605713,-6.927445411682129,-6.2180938720703125 -3825,3825,A225K,-0.148695717,-0.034365795,-0.094658811,-0.014837452,-0.037823987999999996,0.082731238,-0.320280172,0.022888738999999998,0.065313078,0.027824302000000002,-0.09655589099999999,0.062406115,-0.251723737,0.068021586,-0.097696489,0.13225969,-0.207907665,1.151940518,3.077378005,-0.782812352,-0.69283844,-0.283972809,-0.7010866170000001,-1.6045138319999999,-0.6316500629999999,-1.9903555659999999,-0.389093481,-2.656979560852051,-3.447329521179199,-2.747438430786133,-2.9241552352905273,-2.904387950897217 -3826,3826,A225M,-0.057493755,-0.078365413,0.054043667000000004,-0.023300991,-0.048778137,-0.049142832000000004,-0.13633176,0.021344251,-0.079702807,0.076502205,-0.23323303,0.091594505,0.016492829,-0.068346612,0.02174463,0.048512426,-0.146068699,1.118077568,2.6982633689999997,-4.993606757,-4.686563904,-4.779492858999999,-5.315409767,-5.4346502,-4.751917053000001,-5.232160787,-4.307322029,-7.737604141235352,-8.834423065185547,-8.132732391357422,-8.783390045166016,-8.246940612792969 -3827,3827,A225L,-0.021005656,-0.076143294,-0.019279668,-0.028526079,-0.130718286,-0.01122536,-0.09153752300000001,0.049526212,-0.035036231,-0.05116310599999999,-0.10112348199999999,-0.046999112999999995,0.008439778,-0.053972769000000004,-0.0030793879999999997,-0.091974795,-0.169461776,1.4055818780000002,2.302168178,-4.223655783,-3.8263709789999996,-4.3408155289999995,-4.518628075,-4.75940963,-3.673054703,-5.152114678,-3.055797478,-6.062056064605713,-7.3446855545043945,-7.034491062164307,-7.853266716003418,-6.83745002746582 -3828,3828,A225N,0.032214445,-0.028770424,-0.019696102,0.076029205,-0.054190920999999996,0.0382627,-0.011809746000000001,0.076238636,0.054575955999999995,-0.085459816,0.027918969,0.049258315999999996,-0.088650519,0.05356567,0.09849273900000001,-0.007299239,-0.101082602,1.272442012,2.737469258,-2.848377235,-3.177025925,-2.44598616,-2.549922005,-3.5373616180000003,-2.531590469,-3.2964334980000003,-2.506198964,-4.126036167144775,-5.527680397033691,-4.6784281730651855,-5.732499599456787,-5.080111026763916 -3829,3829,A225Q,-0.014750981000000002,-0.129096663,-0.06423234900000001,-0.09174298199999999,-0.146481261,-0.07110552,-0.045210942000000004,0.01570898,-0.05786576,-0.145202953,-0.112990373,-0.038463676,-0.09000102199999999,-0.028969217999999998,-0.15451674599999998,-0.061886990999999995,-0.23107553,1.299251671,2.391722178,-1.887291469,-1.717340775,-1.574923637,-1.8604472580000002,-2.831227745,-1.452517929,-2.060792222,-1.576322918,-3.3904612064361572,-4.254673957824707,-3.3130321502685547,-4.1301798820495605,-3.961064100265503 -3830,3830,A225P,0.008288088,-0.062441776,0.013205903,0.009265303,-0.066311541,0.006686353000000001,-0.037760043,0.054336218,0.015350299,0.000488233,-0.125371785,0.012330932,0.014080873,-0.0034789120000000002,0.022009517000000003,-0.009212706,-0.123410375,1.223670094,2.457657378,-2.177931781,-1.7579258880000002,-2.307343948,-2.69355027,-2.539570473,-1.591268326,-3.389874228,-0.418896018,-4.372699737548828,-4.752254486083984,-3.9750566482543945,-5.306045055389404,-3.868774652481079 -3831,3831,A225S,-0.018873985,-0.010810676000000002,0.032625365,-0.021249774,-0.070292569,-0.025566332,-0.079845248,0.042097277999999995,0.052108367,0.023076122,-0.044697473,0.03927969,0.025971038999999998,-0.004677532,-0.037822015,-0.02328008,-0.117305058,1.4567241130000002,2.579772302,-1.377313597,-1.521993439,-1.282395828,-1.112515625,-1.5949427569999999,-1.3747203369999998,-2.6919811730000003,-0.971199368,-3.6034066677093506,-4.428590297698975,-3.9295454025268555,-4.95046854019165,-3.843329668045044 -3832,3832,A225R,-0.040886043999999996,-0.048941272,-0.022352569,-0.020345929,-0.074905372,0.00960336,-0.07475165,-0.007020436999999999,-0.004754494000000001,0.016092866,-0.113975409,-0.00977957,-0.034925568,-0.021663825,-0.019028032,-0.037499945,-0.112310798,1.232750588,2.504239626,-2.7791266739999996,-3.120920845,-2.36272728,-2.980047569,-3.641244705,-1.79069297,-2.8590896530000003,-1.548018353,-5.194176197052002,-6.072394371032715,-5.258514881134033,-6.193271636962891,-5.439937114715576 -3833,3833,A225T,-0.017775801,-0.12434318,-0.041495997,-0.044757270999999994,-0.144877326,0.014014756000000001,-0.047225048,0.011673447,0.027018551000000002,-0.070970657,-0.177715703,-0.038408948,-0.044583045,-0.032585052,-0.05692948900000001,-0.084233226,-0.205521425,1.347373481,2.2838973069999997,-1.7287782680000001,-1.656881676,-1.613850487,-1.7497052309999999,-1.7448476030000002,-1.878606346,-1.49824478,-1.674361189,-4.376612663269043,-5.0778489112854,-4.490373611450195,-5.293815612792969,-4.827365398406982 -3834,3834,A225W,-0.027560495,-0.017800176,-0.022851985,-0.022187828,-0.17869479300000002,-0.004249681,-0.090666174,0.035545185,0.10317656300000001,0.06284732400000001,-0.098447676,0.053126828,-0.098830797,0.013340668,-0.057716324000000006,-0.16709210300000002,-0.190297482,1.4116154459999999,2.216937685,-7.528216719,-7.486145812999999,-7.6686252370000005,-7.35643013,-8.133568207,-6.9963142089999995,-7.290576706,-6.501824432,-10.852699279785156,-12.340415954589844,-11.091670989990234,-13.107845306396484,-11.224571228027344 -3835,3835,A225V,-0.037921393,-0.103804194,-0.0066078000000000005,-0.0033735109999999996,-0.062278785,0.025120853999999998,-0.036165072,-0.039677713999999996,0.008304811,-0.009016841999999999,-0.198591545,0.032793439,-0.046009037999999995,1.25e-05,-0.006759522,-0.014381926000000001,-0.110175644,1.2700313540000001,2.57458469,-3.24142946,-2.8649228669999998,-3.127967552,-3.4420184860000003,-3.7862282260000004,-2.98601017,-4.076565566,-2.8482612919999997,-5.835934638977051,-6.299662113189697,-6.091551303863525,-6.145022392272949,-6.013311386108398 -3836,3836,A225Y,-0.065546067,-0.051310630999999995,0.057600605,0.004113691,-0.11189530800000001,0.069445915,-0.141781051,0.010688917,0.13789556,0.025349682000000002,-0.127970943,0.121557728,-0.006356518,-0.066054815,0.074282196,-0.027352427999999998,-0.196438188,1.21964132,2.419470378,-5.048541177,-4.907087624,-4.985202652,-4.908190796,-6.047012924,-4.395211891000001,-5.191748705,-3.511729462,-8.16474437713623,-9.640735626220703,-8.606602668762207,-10.43505859375,-9.037824630737305 -3837,3837,G226A,-0.02805829,-0.008594361,-0.042628081,-0.012893183999999999,-0.474043585,0.017153184,-0.061509053,0.005392473,-0.0008197969999999999,-0.017220322,3.16e-05,-0.047420372,-0.037835789,-0.017984188,-0.007802179,-0.375837326,-0.5722498429999999,1.370338457,1.85427305,-4.512396277,-4.535204086,-4.306642883,-4.881706207,-4.999916077,-3.8385121310000003,-4.623638332,-2.5004067819999998,-6.77844762802124,-7.1966447830200195,-8.539971351623535,-5.7180023193359375,-6.960518836975098 -3838,3838,G226C,0.035869467,0.017077352,-0.044959525,0.015524891,-0.89099476,-0.001515506,0.054589501,0.017149433000000002,-0.011385761000000001,-0.024339687000000002,0.05849439,-0.08295699599999999,-0.006962053,-0.047871215,0.078920997,-0.710726511,-1.0712630090000002,1.06899582,1.4958045830000002,-7.252169215,-6.894107636,-7.4839680710000005,-8.181685349,-7.275459587,-6.425625435,-7.821726066,-5.5750201960000005,-10.668182373046875,-11.846750259399414,-12.907245635986328,-9.909753799438477,-10.705415725708008 -3839,3839,G226E,0.010656361000000001,0.081637855,-0.005545491,0.031012842000000002,-0.084602038,0.014853399,0.05660521599999999,-0.035292495,0.054098898,0.049086527000000005,0.11418918300000001,-0.05462546099999999,0.04353448,-0.011447423,0.073473106,-0.125306422,-0.043897654,1.310944878,2.168496629,-4.419818418999999,-3.53692765,-4.866738403,-5.543896584,-4.694132568000001,-3.457396889,-4.410608713,-1.7928719430000002,-5.15190315246582,-5.957027435302734,-5.397428512573242,-5.139689922332764,-5.589899063110352 -3840,3840,G226D,-0.001510372,0.007327787,-0.000857558,0.03638795,0.012588812,-0.003148563,0.02769337,-0.030714112999999998,0.016805444,0.01672662,-0.002071046,-0.014987226000000001,0.013272111000000001,0.008895711,0.063880188,-0.005611049,0.030788672000000003,1.2976643,2.624384642,-2.316870998,-1.888723701,-2.40872509,-2.7877172160000003,-2.342844711,-2.156344269,-2.49368057,-0.721205249,-3.6923093795776367,-3.81948184967041,-3.962090492248535,-3.6688311100006104,-3.1601157188415527 -3841,3841,G226F,0.034473617000000005,0.026400036,0.023914217999999998,0.00819226,-1.399590085,-0.017545441999999998,0.042021437,0.026925797,-0.067609455,0.02307128,0.029728792,0.039856255,0.00797218,0.045698359,-0.02931384,-1.530511788,-1.268668382,0.33883221799999996,1.304335829,-8.006319984,-7.711168953,-7.644680107,-8.704994492,-9.071811653,-6.898944717000001,-6.592626961000001,-5.321523658,-10.234448432922363,-11.092645645141602,-12.455572128295898,-10.107075691223145,-10.299240112304688 -3842,3842,G226I,-0.048287647999999996,-0.024780552999999997,-0.445642384,-1.83792246,-2.3224547269999998,0.01028465,-0.082603049,-0.013972247,-0.135725275,-0.060524573,0.010963468,-0.259115844,-0.632168924,-1.990930537,-1.6849143819999999,-2.120968565,-2.5239408880000003,1.82469744,0.814229192,-8.049840837,-7.522062531,-8.316318092000001,-8.482666344,-8.651759941,-7.276397277999999,-7.016258183,-5.423042743,-9.730489730834961,-11.375419616699219,-12.399681091308594,-8.93452262878418,-10.613628387451172 -3843,3843,G226H,-0.045574919000000005,0.006194538,-0.056825182,-0.002253544,-0.082656357,-0.008806224,-0.04243418400000001,-0.048715654000000004,0.05835067,0.014920213,-0.002531138,-0.068281532,-0.045368832000000005,-0.027263767,0.022756679,-0.064943743,-0.100368971,1.381689683,2.4442826109999998,-5.211127379,-4.786181442,-4.965749077,-6.075291275,-6.2903984070000005,-3.9380166930000002,-4.555310961,-3.557677144,-6.682618141174316,-7.227720260620117,-7.393596172332764,-5.878845691680908,-4.9543070793151855 -3844,3844,G226K,-0.048999945999999996,-0.013593891,-0.053575552,-0.014748637,-0.013250524,-0.027783641,0.009669005999999999,-0.10766889800000001,-0.292269182,-0.039045781,0.011857999,-0.08906010199999999,-0.018091002,-0.048995054,0.01949778,-0.136923147,0.11042209900000001,1.508442457,2.246936704,-5.646548543,-4.679388321,-5.883714485,-6.885149879,-6.371074875,-4.413415154,-5.855281364,-2.8634250519999997,-6.679457187652588,-7.423660755157471,-7.090193271636963,-5.538848876953125,-6.334963798522949 -3845,3845,G226M,-0.026654239,-0.014913383,-0.031927095,0.000981908,-1.588387768,-0.02007503,-0.031595765,-0.021712712000000002,-0.09433259,-0.011836813,-0.017989953,-0.037746581,-0.026107609,-0.006273919,0.008237734,-1.138073793,-2.0387017430000003,0.768026743,1.353773902,-9.601171872,-8.837311118999999,-9.347448425,-10.64593247,-10.194813499999999,-8.980353844,-9.027558469,-7.580752578999999,-10.647472381591797,-10.949163436889648,-12.009727478027344,-9.14366340637207,-10.807853698730469 -3846,3846,G226L,-0.024114795,0.024781845,-0.038626556,-0.10156713099999999,-1.89747051,0.034083142999999996,-0.028336232000000003,-0.019893357,0.023011412000000002,0.013687923999999999,0.035875765,-0.07616727,-0.0010858410000000001,-0.048730841,-0.15440342099999999,-1.807331552,-1.987609468,0.90461726,1.3154172690000001,-7.574734381,-6.7157064129999995,-7.389773368999999,-8.160457016,-8.588859001,-7.0188761060000004,-6.485994681,-3.723148487,-9.488997459411621,-10.716706275939941,-11.68938159942627,-8.80215072631836,-9.525388717651367 -3847,3847,G226N,-0.054262095999999996,-0.031425987,-0.033606435,0.019276097,-0.127757168,-0.055398385999999994,-0.013601084,-0.09492310699999999,-0.013304963000000001,0.012271216000000001,-0.07512319,-0.039864823,-0.027348047,0.028072395,0.010479799,-0.06811379,-0.187400546,1.3251653490000002,2.451458733,-3.3642391910000002,-3.001116287,-2.881685814,-4.7115084000000005,-3.644910484,-2.581974968,-4.268713261,-2.008772011,-4.519999980926514,-4.884084224700928,-4.799637794494629,-3.709538459777832,-3.5452661514282227 -3848,3848,G226Q,-0.007904064,0.003729653,-0.042252909000000005,0.043681387,-0.17476312800000002,-0.013634443000000001,0.049093704,-0.064901831,0.034445239,0.012555161,-0.005095855,-0.063788099,-0.020717718,0.066289044,0.021073729,-0.156931125,-0.19259513,1.335292827,2.197548525,-5.72221434,-4.595090385,-5.733821892000001,-6.965627434,-6.712464637999999,-4.6040673519999995,-5.35394025,-3.510136159,-6.77059268951416,-7.115335464477539,-6.778250217437744,-5.41834831237793,-5.986807346343994 -3849,3849,G226P,-0.009819404,-0.014950278999999999,-0.054511883,-0.016321519,-1.5035684390000001,0.027223159,-0.023441224,0.003802417,-0.015233021999999999,-0.021562249,-0.008338308000000001,-0.079119535,-0.029904231,-0.017912513999999997,-0.014730523,-1.579287631,-1.4278492459999998,0.752758189,1.3204454140000002,-7.323920963,-7.639528946,-7.497563339,-7.601591553,-7.941372078,-5.939548897000001,-6.775898057999999,-4.017059638,-8.99462604522705,-9.48162841796875,-8.102702140808105,-7.55747652053833,-9.212773323059082 -3850,3850,G226S,-0.0035022609999999996,0.015074522,-0.038332658,-0.014338116000000001,-0.060375297,0.009052911,-0.023576791,0.01657227,0.030249729,0.025001329,0.005147714,-0.039071832,-0.037593483999999996,-0.021507017000000003,-0.007169215,-0.05512159,-0.065629004,1.392357865,2.486617971,-3.297024084,-3.309308258,-3.275399559,-3.914904922,-3.0358373260000002,-2.949670357,-4.184662327,-2.211067685,-5.471256256103516,-5.731621742248535,-6.172760486602783,-4.446038722991943,-5.094603061676025 -3851,3851,G226R,0.023698355,0.01679643,-0.014131283,-0.0028417359999999997,-0.160583026,-0.03691833,0.01552629,0.03187042,-0.05884279,-0.007989091,0.041581951,-0.056470299,0.028207733999999998,-0.026471572999999998,0.020788101,-0.188644649,-0.132521403,1.469607535,2.169485859,-5.516256796,-4.734888077,-5.770504234,-6.416279892,-6.222399574,-4.437212204,-5.466075295,-3.354608817,-7.670069694519043,-7.997804641723633,-8.03111743927002,-6.31254243850708,-7.447727203369141 -3852,3852,G226T,-0.002206326,0.003734652,-0.030094608,0.003821777,-0.033124862000000005,-0.019254309,-0.023206922999999997,0.018794272,-0.062733604,0.008935643,-0.0014663389999999999,-0.018085349,-0.042103866,-0.013279501,0.020923054,-0.043562055999999995,-0.022687667,1.4118036330000001,2.5506220490000002,-3.472849811,-3.03690741,-3.773463074,-4.113892174,-3.395925255,-3.044061142,-4.665947301,-2.270424481,-6.039801597595215,-6.083611011505127,-7.147387981414795,-4.954672813415527,-5.358612537384033 -3853,3853,G226W,-0.028769767,0.067235348,-0.008073909,-0.080928001,-1.6450957430000002,0.093826928,0.0025836220000000003,-0.060123156,-0.062176459,0.047387577,0.087083119,0.016501294,-0.032649111,-0.004133508,-0.15772249300000002,-1.7582816680000002,-1.5319098169999998,0.6182098570000001,1.305969224,-8.481391104,-7.580779137,-8.516111648999999,-9.605213219,-9.217799141,-7.487052376,-7.682862413,-5.829208481,-10.095857620239258,-11.799354553222656,-12.947830200195312,-11.344343185424805,-11.080986022949219 -3854,3854,G226V,-0.020969047,-0.010163548,-0.071702969,-1.4359457290000002,-2.483838409,0.024021783999999997,-0.008415799,-0.033522295,-0.015151343999999999,-0.027966539,0.0076394440000000004,-0.145080286,0.0016743489999999999,-1.24033601,-1.631555448,-2.207646741,-2.760030076,2.324857677,1.4806199740000001,-7.241664972000001,-6.770716202000001,-7.769955199999999,-7.547092834,-7.889609901,-6.230950722,-6.50040679,-4.624450349,-9.142792701721191,-10.266765594482422,-11.132283210754395,-7.849217891693115,-9.533636093139648 -3855,3855,G226Y,-0.041627339,0.07340824,-0.006023717,0.005454194,-1.292676546,0.035901733,0.027611065,-0.110865743,0.009028154,0.048667668,0.098148811,-0.051107792,0.039060357999999996,0.072394721,-0.061486333,-1.1619615079999999,-1.423391584,0.547229362,1.3284864,-7.321787129,-6.930771194,-7.39348912,-8.169059464,-8.195932953,-5.919682915,-6.696968619,-3.626706397,-9.230772972106934,-10.133968353271484,-10.742362976074219,-8.982966423034668,-8.09701919555664 -3856,3856,W227A,-0.047163357999999996,-0.054309790999999996,-0.528130314,-1.902446588,-2.410115861,0.002412776,-0.066254225,-0.02807249,-0.00578764,-0.09404905,-0.014570531999999999,-0.42170382,-0.6345568079999999,-2.0510341640000003,-1.753859012,-2.659829754,-2.160401967,1.512285839,0.7055132279999999,-8.749722006,-6.350812096,-11.92763999,-6.505862175,-8.602806091,-10.36148968,-5.185798733,-1.447156194,-7.256782531738281,-10.737377166748047,-10.640357971191406,-9.542820930480957,-8.577496528625488 -3857,3857,W227C,-0.040011906,-0.15387434,-1.444023789,-2.277929629,-2.601610509,0.028663967999999998,-0.037310162,-0.042713649000000006,0.038556913,-0.073734023,-0.234014657,-1.52344397,-1.3646036069999998,-2.385730945,-2.1701283119999997,-2.430255105,-2.772965912,0.69745505,0.032924532,-10.45614405,-8.840139519,-13.39540939,-8.21285157,-9.891450417,-11.94086938,-7.479619059,-5.837160653,-8.887677192687988,-11.136556625366211,-11.403196334838867,-9.539205551147461,-8.455913543701172 -3858,3858,W227E,-0.067131705,-1.326228142,-2.115266861,-2.633820115,-2.874335284,-0.0007340889999999999,-0.067666084,-0.066597325,0.040218174,-1.274348821,-1.378107463,-2.178138719,-2.052395003,-2.961244448,-2.306395781,-2.704738612,-3.043931955,0.133360591,-0.7830992240000001,-12.66754355,-10.06290546,-16.13431291,-10.46113841,-12.61191255,-14.06744842,-8.729899453,-5.767169502000001,-8.842947959899902,-12.838394165039062,-12.5416841506958,-12.270142555236816,-11.944503784179688 -3859,3859,W227D,-0.052516707999999995,-1.175514232,-2.696327174,-2.825804803,-2.779304338,0.004722863,-0.08643041800000001,-0.018602998,0.064698208,-1.1511329890000002,-1.199895474,-2.485047579,-2.9076067689999996,-2.569183304,-3.0824263010000004,-2.914737459,-2.643871216,0.129055662,-0.721305704,-11.16212465,-8.867377159,-13.51814839,-9.096855292999999,-11.32721093,-13.00103146,-7.680339245,-5.6909617379999995,-9.108409881591797,-12.841728210449219,-12.01793098449707,-11.998573303222656,-11.905406951904297 -3860,3860,W227G,-0.08444311300000001,-0.054982210999999996,-1.4654331809999999,-2.2373264180000003,-2.958552135,0.0015584770000000002,-0.072234613,-0.096651612,-0.024340168,-0.019363104,-0.09060131699999999,-1.38151678,-1.549349581,-2.144878451,-2.329774385,-2.717676388,-3.199427881,0.88235344,0.075050397,-11.76640475,-8.953498878,-14.83887833,-9.395959297000001,-11.54829469,-14.09539256,-8.130351702999999,-5.480871175,-7.190857410430908,-11.333889961242676,-11.256768226623535,-10.510847091674805,-8.264404296875 -3861,3861,W227F,-0.0035534140000000004,0.036031292,-0.033449549,-0.048965037999999995,-0.845939091,-0.019739182,0.038371537000000004,-0.045478365,0.02302182,-0.001757668,0.073820252,-0.034831952,-0.032067146,-0.08267582400000001,-0.015254252,-0.692388615,-0.999489567,1.211021003,1.5593081469999999,-7.694531615,-5.918701134,-11.14873684,-6.565628654,-6.8721570210000005,-7.967434425,-5.7505161,-3.7634479410000004,-7.23974609375,-9.70323371887207,-9.488205909729004,-8.071491241455078,-7.627594470977783 -3862,3862,W227I,-0.062659166,-0.256688769,-1.549722425,-2.609369057,-2.4748229630000003,0.015451241000000001,-0.016284485,-0.10903384599999999,-0.063428035,-0.180457074,-0.33292046399999997,-1.697302348,-1.4021425019999998,-2.480408077,-2.7383300360000002,-2.348840978,-2.600804947,0.9996864540000001,0.013407163,-10.21222814,-8.726114577999999,-13.32373914,-9.132508682000001,-9.424162949,-10.45461537,-7.3617971529999995,-1.989329832,-8.1106595993042,-11.41684627532959,-11.950325965881348,-9.826987266540527,-9.412041664123535 -3863,3863,W227H,-0.04637097900000001,-0.026141255,-0.969336917,-2.262726132,-2.7369220089999997,0.019503267,-0.057128240999999996,-0.035613716000000004,-0.057202917,-0.009049164,-0.043233345,-0.864979948,-1.073693886,-2.2043881780000003,-2.321064085,-2.549942333,-2.923901685,1.881342386,0.6969242440000001,-11.7201346,-9.438374062000001,-15.84491682,-9.273831696,-11.24592738,-12.79762305,-9.290488647,-6.802986395,-8.273677825927734,-11.709718704223633,-10.4690580368042,-9.233386993408203,-10.263164520263672 -3864,3864,W227K,-0.037043001,-1.471868894,-2.325454961,-2.255962585,-2.859977118,-0.007116854000000001,-0.023414056000000003,-0.050671945999999995,-0.05430162,-1.55767317,-1.386064618,-2.268338469,-2.382571452,-2.352474194,-2.159450976,-2.999058345,-2.720895891,-0.005323496,-0.9825087029999999,-12.10586356,-9.57906134,-15.05113855,-10.20826182,-12.51061022,-13.18024586,-8.25227111,-5.672781251,-9.715858459472656,-12.293395042419434,-11.914051055908203,-11.27967643737793,-11.642452239990234 -3865,3865,W227M,-0.026012373,0.016057956,-0.11031298,-1.76822655,-2.730242755,-0.034871807000000005,-0.060019227,0.007994481,0.062069125999999995,0.006674494,0.025441417999999997,-0.159248914,-0.061377046,-1.541060993,-1.9953921069999998,-2.699528505,-2.760957005,1.081009437,0.737911742,-11.07819212,-9.718278182999999,-14.46238187,-9.167197685,-10.37966915,-11.66343374,-7.053809461,-4.217516955,-8.370722770690918,-11.068639755249023,-11.042558670043945,-9.397982597351074,-9.109233856201172 -3866,3866,W227L,-0.037928803,-0.598327783,-2.0707466390000002,-2.386417219,-3.214010768,0.030487862,-0.041082403999999996,-0.034775201,-0.023291243,-0.588438196,-0.608217369,-2.216433922,-1.925059355,-2.4766609059999998,-2.296173532,-3.123245056,-3.3047764789999996,0.843835647,-0.397234795,-8.963415829,-7.2226299439999995,-11.71113733,-7.702530777000001,-8.295966629,-9.884814468,-6.149481142000001,-2.836913527,-8.185236930847168,-10.163318634033203,-10.411063194274902,-8.602163314819336,-7.654657363891602 -3867,3867,W227N,0.015379357,-1.227838038,-2.627131956,-2.606094587,-2.4715484930000002,0.00521904,-0.01679854,0.04755725400000001,0.014100014,-1.019520002,-1.436156073,-2.462579061,-2.7916848510000003,-2.546714786,-2.6654743869999997,-2.4151476869999997,-2.5279492980000002,0.45948966399999996,-0.64814349,-13.08268429,-10.35125268,-15.57599986,-10.69797279,-13.31829711,-15.46989901,-9.854672592,-7.321889477,-9.531695365905762,-12.323917388916016,-11.810325622558594,-10.581329345703125,-11.22789192199707 -3868,3868,W227Q,-0.035924184,-1.027905073,-2.0845003930000003,-2.184982048,-2.740541574,-0.001838448,-0.065097527,-0.006750841,0.066486328,-1.1027656909999999,-0.953044455,-2.1936422319999997,-1.9753585530000002,-2.15283922,-2.217124875,-2.623332112,-2.8577510360000002,0.15023451,-0.6905365590000001,-12.87795307,-10.52295752,-15.66330035,-10.96900449,-13.52001027,-13.71449273,-9.279431646,-6.66516427,-8.723682403564453,-11.18420124053955,-11.188776969909668,-10.03892707824707,-10.472921371459961 -3869,3869,W227P,-0.047805659,-1.7244401969999998,-2.1673092030000003,-2.44252917,-3.5768926239999996,-0.013242971000000001,-0.060834267000000004,-0.03477705,-0.13185349400000002,-1.819835536,-1.6290448569999998,-2.00762209,-2.326996315,-2.34703032,-2.53802802,-3.6925844760000004,-3.461200771,-0.232599361,-1.11399797,-12.77688132,-10.23978833,-15.77915876,-10.63560801,-13.30776341,-13.92208809,-8.144402863,-4.822564772,-10.865049362182617,-13.997267723083496,-14.187715530395508,-12.723732948303223,-12.203897476196289 -3870,3870,W227S,-0.055388977,-0.042426411,-1.055911735,-2.285489605,-3.230124757,0.017154039,-0.05898078599999999,-0.051797168,-0.014345718,-0.066262712,-0.01859011,-0.837305693,-1.274517776,-2.266324697,-2.304654513,-3.51496884,-2.9452806739999997,1.7399079430000002,0.596421914,-10.37615052,-8.173360168,-12.73343616,-7.5462295610000005,-10.55875982,-12.86896691,-7.1572535,-3.0928075789999996,-6.952879428863525,-10.30961799621582,-10.095190048217773,-8.876093864440918,-7.796426773071289 -3871,3871,W227R,-0.062827882,-1.4570845159999999,-2.071461297,-2.585293772,-2.587686553,0.02215222,-0.053707065,-0.07194869799999999,-0.004433616,-1.4037141819999999,-1.51045485,-2.132604302,-2.010318291,-2.760808071,-2.409779472,-2.667029533,-2.508343572,0.157776742,-0.862477534,-11.21733548,-9.086990692,-13.78438659,-9.17543618,-11.57565248,-12.46421144,-8.321001857,-5.865106355,-8.626863479614258,-10.521735191345215,-10.442516326904297,-7.877042293548584,-9.205024719238281 -3872,3872,W227T,-0.057075614000000004,-0.02174628,-1.133980669,-2.343091463,-2.9471059960000003,0.076552392,-0.043108952,-0.071042276,0.064523816,-0.031754459,-0.011738101,-1.019316074,-1.248645264,-2.148774778,-2.537408148,-2.649230893,-3.244981099,2.033591494,0.751278268,-10.04969238,-7.627598534,-12.86571387,-7.803569435,-10.35474218,-11.59683789,-7.26029241,-1.298083407,-6.053139686584473,-9.666924476623535,-9.953390121459961,-9.054210662841797,-8.105326652526855 -3873,3873,W227V,-0.09485918300000001,-0.10501336800000001,-1.496315531,-2.249577294,-3.138425058,0.018926157,-0.101502615,-0.088215751,-0.038217254,-0.062679974,-0.147346762,-1.41489565,-1.5777354119999998,-2.260792209,-2.238362378,-2.958528882,-3.3183212330000003,0.880890257,0.072333904,-8.669829672,-7.087214264,-12.04006367,-7.335103584,-7.824304497000001,-9.062462349,-6.60490433,-0.823204093,-7.488635063171387,-10.888124465942383,-11.0311918258667,-9.32666301727295,-8.43924331665039 -3874,3874,W227Y,-0.120906119,-0.014422706,-0.032958013,-0.044935314000000004,-2.100840027,-3.16e-05,-0.150033655,-0.091778582,0.005579577,0.052028958,-0.080874369,0.011216606,-0.077132632,0.019530016,-0.109400643,-1.8148311519999998,-2.3868489019999997,0.743221252,1.305462926,-7.571193313999999,-5.681504317999999,-10.23329059,-6.674607315,-7.43728331,-7.829281036,-5.917534932000001,-3.075704734,-6.905811786651611,-9.68053913116455,-7.907545566558838,-7.406045436859131,-7.826702117919922 -3875,3875,F228A,0.034819101,0.10482980300000001,0.038322882,-0.045568097,-0.705757337,-0.098981239,0.009592467,0.060045734,-0.040639287,0.061577249,0.148082356,0.009433944,0.067211819,-0.06506121200000001,-0.026074982000000003,-0.60266673,-0.808847944,1.045491769,1.513181738,-5.168662502,-5.113226021,-5.295019142,-5.796567574,-4.457975243,-5.1805245289999995,-4.338709645,1.260315839,-1.0120625495910645,-6.350777626037598,-2.103635311126709,-0.3204619884490967,-1.27109956741333 -3876,3876,F228C,0.08968447800000001,0.01809077,0.05516087099999999,0.003833366,-1.4227194840000001,-0.133256625,0.055160659,0.124208297,-0.075850467,0.030382628999999998,0.0057989109999999995,0.001175358,0.109146384,-0.039480857,0.047147589000000004,-1.43038452,-1.415054448,0.872519,1.3392848590000002,-7.171091522,-7.3241817860000005,-6.8818971410000005,-6.62861274,-7.164868477000001,-7.855897468999999,-7.465080819,-3.121832967,-3.052013397216797,-8.498493194580078,-4.217952728271484,-1.9365203380584717,-3.522329807281494 -3877,3877,F228E,0.007750809,-0.0052450280000000005,-0.0007574519999999999,-1.336517625,-2.6497394169999997,-0.097190971,0.017515563,-0.002013945,-0.11044670300000001,-0.000300862,-0.010189194,-0.017984364,0.016469461,-0.999541254,-1.673493996,-2.754895612,-2.544583222,0.7831339070000001,0.76112441,-5.09736897,-4.414539215,-5.941707732999999,-6.213641182000001,-3.8486754530000002,-5.068281265,-3.467671453,1.5606969,-0.7589101791381836,-7.077482223510742,-2.6705827713012695,-1.7482106685638428,-2.718064785003662 -3878,3878,F228D,-0.024903281,0.062555582,-0.649745724,-2.314775154,-2.364827307,-0.09928765099999999,-0.055121671,0.00531511,0.037109206,0.059384499,0.065726664,-0.415136341,-0.8843551070000001,-2.152794341,-2.476755967,-2.226907461,-2.502747153,1.390829997,0.6532372,-6.149703581,-5.375492508,-6.9716711270000005,-6.197008469,-5.752258682000001,-6.45208712,-4.353363582,0.185527642,-1.9212217330932617,-7.9185791015625,-3.7173757553100586,-2.848747968673706,-3.8957343101501465 -3879,3879,F228G,0.063027426,0.068428654,0.061150803,-0.467575016,-2.117396431,-0.099691056,0.040606336,0.085448516,-0.071441785,0.05422977599999999,0.082627532,0.030431014,0.09187059199999999,-0.260459331,-0.6746907,-1.954708506,-2.280084355,1.270993628,1.333423407,-5.954611449,-6.549204926,-6.4892449039999995,-4.585500549,-4.826127716,-7.322979149,-4.12292313,-0.11893282699999999,-1.430464744567871,-7.963726997375488,-3.8557567596435547,-2.2187917232513428,-2.394458293914795 -3880,3880,F228I,-0.035738797999999995,0.09555123300000001,0.059271792999999996,-0.10089648,-1.514573075,-0.033208732000000005,-0.025844499,-0.045633097000000004,-0.15001735300000002,0.189553257,0.001549209,0.07886674099999999,0.039676845,-0.01371353,-0.188079429,-0.834314893,-2.1948312569999997,0.73612221,1.3802270540000001,-3.871866818,-3.604431343,-4.094313042,-4.648792679,-3.370314613,-3.641482414,-3.908425378,1.516578741,-0.7819633483886719,-5.32316255569458,-0.8109622001647949,-0.9045426845550537,-0.46661949157714844 -3881,3881,F228H,0.054301557,0.059061415,0.027849323999999998,-0.055433891,-0.9297338270000001,-0.10441484300000001,0.031796199,0.076806915,-0.074852487,0.08924800000000001,0.028874828999999998,0.014855055,0.040843592000000005,-0.087319198,-0.023548583999999997,-0.688445443,-1.171022211,1.088151176,1.506760747,-3.869861568,-4.963229378,-3.5927679980000002,-2.7115910189999997,-3.68473658,-4.396982864,-4.654227133,-0.108022492,1.2636494636535645,-3.7929880619049072,-0.4583296775817871,0.511878490447998,0.5602865219116211 -3882,3882,F228K,0.08967324,0.056720277,-0.063812484,-0.122202633,-1.376374769,-0.08840174599999999,0.072002464,0.107344016,-0.17296655100000002,0.075568303,0.037872251,-0.14149214599999999,0.013867178999999999,-0.072970171,-0.171435095,-0.925234542,-1.827514995,1.219185529,1.489159541,-4.066990816000001,-4.38103241,-4.525627075,-4.1180619510000005,-4.174996558999999,-3.1352360839999998,-3.2426862819999998,2.137464243,3.5574636459350586,-3.256216526031494,1.8602200746536255,3.1563363075256348,2.8201680183410645 -3883,3883,F228M,0.005584345,0.044304052000000003,0.015649041000000002,-0.072049924,-0.167753136,-0.151367284,0.0020067279999999997,0.009161961,-0.118519518,0.047811779000000006,0.040796324,0.021293647000000002,0.010004434,-0.138107277,-0.00599257,-0.184574143,-0.150932129,1.331223188,2.041398221,-4.476601221,-4.976921379,-4.183011505,-4.049390121,-4.073266037,-5.100417061,-4.237412471,-0.8342781340000001,-1.817263126373291,-6.31785774230957,-1.8880395889282227,-1.4677817821502686,-1.6191768646240234 -3884,3884,F228L,0.016878473,0.067237508,0.044833205,-0.017086541,-1.38825315,-0.057057705,-0.014523362,0.048280308,-0.060330699,0.057245868,0.077229147,0.041523689,0.048142721,-0.070004229,0.035831148,-1.468747165,-1.307759135,0.98882085,1.348733371,-3.421797849,-3.9119002910000003,-2.5376745990000003,-3.3273038789999996,-3.6587394410000003,-3.673371033,-4.238509895,0.8944283059999999,-0.9464263916015625,-5.214033126831055,-0.9229693412780762,-0.9208695888519287,-0.6271071434020996 -3885,3885,F228N,-0.098818831,0.1554642,0.082388889,-0.043138267,-2.058817623,-0.077984931,-0.15331145599999998,-0.044326205,0.003440215,0.240461662,0.070466737,0.152238611,0.012539167,0.019575036,-0.10585157,-1.87408202,-2.243553226,0.620598587,1.300176463,-5.324353757,-5.43412072,-5.432065063,-4.536406723,-5.625005951,-5.594170326,-5.258665037,-0.081957632,0.019318580627441406,-5.2984209060668945,-1.3245735168457031,-0.08326458930969238,-0.6889934539794922 -3886,3886,F228Q,0.083771655,0.144144313,0.065153763,-0.069929773,-1.501144034,-0.083237594,0.066237532,0.10130577800000001,-0.106043415,0.104261359,0.184027267,0.086501066,0.043806459000000006,-0.041672925,-0.09818662,-1.5856080609999998,-1.416680006,0.700612841,1.3170379190000001,-4.183064699,-4.78273922,-4.395836441,-3.9499811780000003,-3.77038089,-4.016385765,-3.0290243639999996,1.50933927,1.1681714057922363,-4.7774858474731445,-0.17182636260986328,1.1275296211242676,0.022648334503173828 -3887,3887,F228P,0.013825108000000001,-0.712075188,-2.204574912,-2.550107461,-2.9293356910000004,-0.060439926,-0.001243225,0.02889344,-0.0036822609999999996,-0.626285973,-0.7978644020000001,-2.410693656,-1.9984561680000001,-2.4951391419999998,-2.60507578,-2.775306745,-3.083364636,0.375239692,-0.528984935,-5.770727083,-7.182700287,-4.007586029,-6.380903625,-4.313259193,-6.969186279,-4.857002713,1.172139024,-0.5869669914245605,-7.523983955383301,-2.970160961151123,-1.714994192123413,-2.2345213890075684 -3888,3888,F228S,0.033219423,0.092614051,0.049866852999999996,-0.034156986,-1.232204024,-0.09031324199999999,0.035132136,0.03130671,-0.037012462,0.068632179,0.116595923,0.035631919,0.064101786,-0.07103567200000001,0.002721701,-1.093353346,-1.371054701,1.008833687,1.39886342,-3.487704623,-3.6733709489999997,-3.4820455089999998,-2.858377022,-3.65195256,-3.7727770769999998,-3.2485395039999996,1.208492804,0.24921321868896484,-4.6155571937561035,-1.3147926330566406,0.38544559478759766,0.2498607635498047 -3889,3889,F228R,0.035772611,0.080506595,0.051593198,-0.023338256,-1.14201242,-0.070295346,0.031534207,0.040011015,-0.076658189,0.102148642,0.058864547,0.061632592,0.041553803,-0.051694437,0.005017925,-1.169159546,-1.1148652940000001,0.864773419,1.3590320230000001,-4.7086980160000005,-5.316103622,-4.486409752,-4.138878761,-4.515474533,-5.086623413,-2.411800269,2.6686776130000003,3.2556800842285156,-2.80599045753479,1.6266604661941528,2.5237350463867188,3.705448627471924 -3890,3890,F228T,0.040537346,0.019403695,0.004287443,-0.080922555,-1.022036606,-0.103798664,0.021386807,0.059687885,-0.08235759,-0.033483714,0.072291103,0.00657039,0.002004495,-0.13765627,-0.024188839,-1.040710192,-1.00336302,1.138127468,1.4355649080000001,-3.799296155,-3.161730927,-3.719481552,-4.184201584,-4.234009308,-3.6970574039999997,-2.8165484839999997,2.449725001,1.0925159454345703,-3.9837350845336914,0.4232625961303711,1.1626341342926025,0.6343259811401367 -3891,3891,F228W,0.04264328,0.004783932,0.018125335,-0.04195293,-0.20135755800000002,-0.07806152200000001,0.028096977999999998,0.057189580999999996,-0.0062953869999999995,-0.020114455,0.029682318,0.0033666409999999996,0.032884027999999996,-0.041478205,-0.042427654,-0.18450714899999998,-0.218207967,1.583149769,2.310440244,-4.835200641,-5.1613421939999995,-4.055635605,-4.667095711,-4.736917007,-5.555012688,-5.584854934,-1.092872427,-3.9744458198547363,-8.176557540893555,-4.774913787841797,-3.6226956844329834,-3.332749843597412 -3892,3892,F228V,-0.0015192,0.071191963,0.044245122000000005,-0.056016408,-0.947842669,-0.092051485,-0.029686123,0.026647723999999998,-0.075979632,0.095450265,0.04693366,0.048900725,0.039589519,-0.06332888099999999,-0.048703934000000004,-0.7373337670000001,-1.1583515709999999,0.9369956159999999,1.442488393,-4.34699781,-4.07201783,-4.574214615,-4.7294993739999995,-4.00350502,-4.355752213,-4.063435392,2.198252874,-0.4653778076171875,-5.02516508102417,-0.28909873962402344,-0.26213526725769043,-0.3363914489746094 -3893,3893,F228Y,0.083847173,0.059318418,-0.047205919000000006,-0.054358355,0.082612214,-0.08908438699999999,0.09536891800000001,0.072325427,-0.076910254,-0.008512641,0.12714947599999998,-0.041512901,-0.052898935999999994,-0.08735501400000001,-0.021361696,0.031694729,0.133529698,1.209169271,2.751116301,-0.9576026209999999,-1.002206535,-0.9138741459999999,-0.859307571,-0.9619984659999999,-1.050626389,-2.5550118719999997,-0.956348581,-2.1301450729370117,-4.602472305297852,-3.6112022399902344,-3.3606388568878174,-2.404146671295166 -3894,3894,I229A,-0.069410175,-0.009194266999999999,-0.022617725,-0.498010987,-2.164150476,-0.047322728,-0.058249232000000005,-0.080571118,-0.025520719,0.044674723,-0.063063257,0.059230841,-0.10446629,-0.140983006,-0.855038968,-2.051746359,-2.276554592,0.986912628,1.302322145,-8.416061873,-6.684182381,-8.170437576,-8.217985657,-7.841819762999999,-11.16588399,-5.843884611,-1.729619459,-6.067755699157715,-7.662337779998779,-7.1192307472229,-6.367105960845947,-7.81389856338501 -3895,3895,I229C,-0.018434574,-0.038239933,-0.00527992,-0.03924641,-0.26286681300000003,-0.021814132000000003,0.005045292,-0.041914439,0.007929562,-0.022655197999999998,-0.053824668,0.07778862,-0.088348459,-0.01172377,-0.066769049,-0.251743379,-0.273990247,1.203413474,1.873144023,-10.74783069,-9.858151581,-10.27910246,-11.79328159,-9.773461304,-12.03515653,-7.4469440989999995,-3.797866888,-7.584922790527344,-9.916223526000977,-8.790630340576172,-8.060293197631836,-11.280582427978516 -3896,3896,I229E,-0.118163448,-0.204449049,-1.606157646,-2.408972436,-2.863877939,-0.00018130599999999997,-0.093616218,-0.14271067699999998,0.010441283,0.00047137199999999996,-0.40936947,-1.5450958940000001,-1.667219398,-2.470514563,-2.347430309,-2.609540769,-3.118215109,0.557465311,0.02243671,-12.00268332,-10.11901456,-12.04317039,-12.14820953,-10.24863245,-15.45438969,-8.45180826,-5.495237653999999,-8.806783676147461,-10.585600852966309,-9.117036819458008,-10.920048713684082,-11.826460838317871 -3897,3897,I229D,-0.036650925,-0.530136698,-1.819078912,-2.1181931940000003,-2.8901132960000004,-0.031067167000000003,-0.013327668,-0.059974180999999994,-0.012719905,-0.26147631600000004,-0.79879708,-1.8746569780000002,-1.763500845,-2.3229543919999998,-1.913431996,-2.859920608,-2.9203059839999996,1.082465498,-0.048597466,-14.4124682,-12.86251445,-14.51752683,-14.76061289,-12.63306866,-17.28861816,-10.72163131,-9.040801153,-9.751900672912598,-10.905917167663574,-10.629061698913574,-11.46329116821289,-13.621387481689453 -3898,3898,I229G,-0.084474875,-0.045300644,-1.45001766,-2.321530954,-2.7583099339999997,-0.048092622,-0.063402845,-0.105546904,-0.04973572,0.01285798,-0.10345926800000001,-1.38423598,-1.51579934,-2.272992663,-2.370069244,-2.7685661930000003,-2.748053674,0.656482615,0.05557492,-12.37320936,-9.398242386,-12.37932755,-13.29583441,-11.61978018,-15.17286228,-7.923392099,-4.333446926000001,-8.648253440856934,-9.905081748962402,-9.134729385375977,-9.0905122756958,-9.38259506225586 -3899,3899,I229F,-0.11250589400000001,-0.05666062,-0.030493907,-1.482905359,-2.078295963,-0.101889922,-0.099795331,-0.125216456,-0.042873300999999996,0.04613657400000001,-0.159457813,0.030374442999999998,-0.09136225699999999,-1.210714747,-1.755095971,-2.066439725,-2.090152201,2.340730752,1.5516690640000002,-9.670601863,-8.691327583,-7.817211334,-11.37656223,-9.782511688,-10.68539648,-6.00651842,-1.495245675,-7.14187479019165,-5.004299163818359,-6.117922782897949,-7.026298522949219,-7.926919937133789 -3900,3900,I229H,-0.082700661,-0.032096909,-1.295386883,-2.106377184,-2.982101441,-0.011462223999999998,-0.041880875,-0.12352044699999999,-0.02844013,-0.011823811000000002,-0.052370006,-1.258517678,-1.332256087,-2.1169895569999997,-2.09576481,-2.9549857680000002,-3.009217113,0.7347734840000001,0.085176321,-14.97365578,-12.65760128,-14.02125831,-15.33147475,-14.20916115,-18.64878344,-9.505399031,-6.0201802120000005,-9.345662117004395,-11.71182632446289,-7.36993932723999,-10.03651237487793,-13.71015453338623 -3901,3901,I229K,-0.05980169900000001,-0.031431826,-1.498162846,-2.30070772,-3.030689638,-0.046516218,-0.022964226,-0.096639171,-0.086822119,0.0005644480000000001,-0.0634281,-1.33702612,-1.659299572,-2.341626035,-2.259789405,-2.9243497410000003,-3.137029535,0.628572103,0.06431168,-14.24863385,-12.90801746,-13.65958093,-14.39900317,-12.33425845,-17.9423092,-10.72610791,-9.063402344,-8.732786178588867,-11.939665794372559,-7.5588459968566895,-10.554208755493164,-13.430274963378906 -3902,3902,I229M,-0.034686191,-0.002498985,-0.006363678,-0.017867238,-0.607769943,-0.054066044,-0.005625576,-0.063746806,-0.049273679,0.045896427999999996,-0.050894398,0.065103162,-0.077830517,0.032555315,-0.06828979,-0.46860607,-0.746933816,0.680750987,1.450953409,-7.612678645,-7.719456772000001,-7.133450409,-9.892551597999999,-7.925485435,-5.392449012999999,-6.642132025,-3.341766762,-6.029060363769531,-6.093334674835205,-6.616581439971924,-6.185148239135742,-7.522131443023682 -3903,3903,I229L,-0.072972947,-0.023108798,-0.031415698,-0.023144424,-1.216477581,-0.100695239,-0.064336139,-0.081609755,-0.04913736900000001,0.026071916,-0.072289511,0.053992976,-0.116824371,0.058049131,-0.104337979,-1.140424698,-1.292530463,0.658855608,1.338664433,-6.81619496,-6.270641006,-5.879656075,-8.929904037,-6.016914757,-6.983858925,-5.272553434,-1.092207017,-3.958742618560791,-4.9526519775390625,-4.8333258628845215,-4.966452598571777,-6.114810943603516 -3904,3904,I229N,-0.083550736,-0.051992474000000004,-0.81172786,-2.243190302,-2.6856840139999996,-0.001593391,-0.057831310999999996,-0.10927016,-0.004905019,-0.008567874,-0.095417073,-0.476507721,-1.146947998,-2.305016377,-2.181364227,-2.74507258,-2.626295447,1.362198087,0.565428192,-13.80432748,-12.07785767,-14.78292802,-14.09083838,-12.32167987,-15.74833346,-9.905708836,-6.6827684110000005,-8.028060913085938,-10.705564498901367,-8.251994132995605,-8.917694091796875,-10.426733016967773 -3905,3905,I229Q,-0.059360261,0.006274115,-1.3743459930000002,-2.3197786469999997,-2.9084872710000003,-0.013432571,-0.035474562,-0.08324596,-0.06129640099999999,-0.001026605,0.013574835,-1.300765153,-1.4479268330000001,-2.210389555,-2.429167739,-2.872294507,-2.9446800339999997,0.637943334,0.06939721900000001,-14.12067794,-12.755091,-14.0205646,-14.24484502,-11.79798397,-17.78490512,-10.72610791,-9.063402344,-8.711233139038086,-10.572705268859863,-8.014528274536133,-10.034479141235352,-11.889183044433594 -3906,3906,I229P,-0.08172216,-1.610386677,-2.262329793,-2.334286207,-2.9799665060000002,-0.014989348000000001,-0.070993975,-0.092450345,-0.106152031,-1.733628547,-1.4871448059999999,-2.262266235,-2.26239335,-2.0067947619999997,-2.661777651,-2.70346182,-3.256471191,-0.160249955,-1.110350261,-13.78547602,-12.33307677,-13.796525599999999,-14.21220858,-12.72580354,-15.85976559,-9.560169155,-6.410978878,-7.76710844039917,-10.040909767150879,-8.781375885009766,-10.796148300170898,-12.359838485717773 -3907,3907,I229S,-0.07371826,-0.036303463,-0.407388759,-2.0365659430000003,-3.095345961,-0.014685356,-0.060980944,-0.08645557599999999,-0.055108184000000004,-0.003009297,-0.06959762900000001,-0.256925732,-0.557851786,-1.926341375,-2.14679051,-2.915605261,-3.2750866610000005,1.27897484,0.701574246,-10.05259946,-8.113501747,-11.09416805,-10.87198161,-9.026331032,-11.15701486,-6.461403316,-2.689590051,-7.079763889312744,-7.972395896911621,-7.809650897979736,-6.170605659484863,-9.319961547851562 -3908,3908,I229R,-0.08818997699999999,-0.15859214300000002,-1.681584515,-2.335897718,-2.89429032,-0.02983625,-0.06344221,-0.112937744,-0.043233282000000005,-0.055508222,-0.261676063,-1.642970694,-1.720198335,-2.249261145,-2.422534291,-2.7148714519999997,-3.073709188,0.7210686740000001,0.006662591,-14.29713226,-12.98181963,-13.76461433,-14.29879346,-12.12302988,-18.31740396,-9.021325447999999,-5.802377582,-8.863157272338867,-11.355469703674316,-7.194942951202393,-9.988744735717773,-13.524503707885742 -3909,3909,I229T,-0.089289656,-0.021184647,-0.53331329,-1.948994764,-2.658762353,-0.015301061999999999,-0.074858868,-0.10372044400000001,-0.021092378,0.0075328159999999995,-0.04990210900000001,-0.278871639,-0.787754941,-1.765362048,-2.132627479,-2.533722331,-2.783802375,1.3245107059999999,0.7369036720000001,-8.751654924,-7.389862885,-8.416578384,-9.533736725,-8.59171357,-9.826383057000001,-5.978377227999999,-1.92299447,-5.688083648681641,-6.870204448699951,-6.043117523193359,-5.94089937210083,-7.742388725280762 -3910,3910,I229W,-0.045147097000000004,-0.025102576,-0.844125942,-2.0345341180000003,-2.7491487269999997,-0.011215716,-0.022435188,-0.067859006,-0.069621072,-0.044462812000000004,-0.005742339,-0.672743717,-1.015508166,-2.2184471980000002,-1.8506210369999998,-2.4331941180000003,-3.065103335,1.6925050730000002,0.65505085,-12.86131018,-11.80160159,-11.50875249,-13.2472619,-11.82041119,-15.92852374,-7.877753956,-2.184050546,-9.666410446166992,-10.559380531311035,-7.515716075897217,-8.942788124084473,-12.681480407714844 -3911,3911,I229V,-0.057768862000000004,-0.03558698,-0.021215455,-0.017933436,-0.30258486,-0.033463746,-0.043185639000000005,-0.072352085,-0.07125168400000001,-0.013481006,-0.057692954000000005,0.07801055400000001,-0.12044146300000001,0.045654115,-0.081520987,-0.268185207,-0.336984512,0.840184521,1.627879045,-3.68025253,-3.483888275,-2.8268575439999997,-3.30088932,-3.981686073,-4.807941437,-5.1185753730000005,0.8082562870000001,-2.6361513137817383,-3.5098748207092285,-3.673135757446289,-3.4313855171203613,-3.202792167663574 -3912,3912,I229Y,-0.059964285,-0.022906887,-0.003197551,-1.574836975,-2.505668973,-0.075255208,-0.03383762,-0.08609095,-0.03263289,0.005723961,-0.051537735,0.077142134,-0.083537235,-1.4169983380000002,-1.732675612,-2.462120042,-2.549217903,0.618889537,0.7050145329999999,-12.20591889,-10.59103956,-10.34467379,-12.83830901,-11.87163364,-15.38393846,-8.466165645,-3.511969808,-7.728940963745117,-8.088210105895996,-6.156272888183594,-8.32971477508545,-11.306133270263672 -3913,3913,A230C,0.07310897,-0.004171958,0.048859207,0.001506142,-0.216393002,-0.053046782,0.009368173,0.13684976699999998,-0.016132043999999998,-0.017617666,0.009273751,0.020522519,0.077195894,-0.022928851,0.025941135,-0.227233328,-0.205552675,1.301847205,1.990501504,-11.00741226,-9.420176544,-11.3167013,-11.21582285,-11.23938133,-11.84497926,-8.591221914,-6.522559779,-8.14981460571289,-10.485176086425781,-8.080577850341797,-10.379502296447754,-10.768445014953613 -3914,3914,A230E,-0.01785081,-0.938637313,-1.8635617880000002,-2.141555238,-2.6446883409999997,-0.029437271,-0.011906507,-0.023795112,0.108199615,-0.8577856759999999,-1.01948895,-2.069408178,-1.6577153969999998,-2.026454942,-2.256655533,-2.6513689680000003,-2.638007714,0.354799882,-0.59052157,-8.183276454,-7.187504477999999,-8.119523651,-8.266883575,-9.182777183999999,-8.159693382,-6.660476608,-4.655544631000001,-9.722973823547363,-10.052900314331055,-8.52365779876709,-11.023355484008789,-10.94200611114502 -3915,3915,A230D,-0.05843501,-1.641969546,-2.02874737,-2.2739014330000002,-2.7435611410000003,-0.06765581,-0.063766253,-0.053103766,-0.0028655779999999997,-1.956292058,-1.3276470340000002,-2.15088122,-1.906613519,-2.2328667209999997,-2.3149361440000003,-3.033872006,-2.453250275,-0.68648166,-1.113512379,-10.55394955,-9.299721893,-10.46668332,-10.8273447,-11.70386594,-10.4721319,-8.086664255,-6.03153719,-10.196320533752441,-9.325098037719727,-9.400659561157227,-11.605538368225098,-12.769375801086426 -3916,3916,A230G,0.025998699,-0.006894561,0.036733964,0.022933474,-0.023878032,-0.045517713,0.019219032,0.032778366,0.015902555,-0.006291191999999999,-0.007497929,0.029334516,0.044133412000000004,-0.004519398,0.050386345,-0.036233859,-0.011522204,1.324008576,2.494239028,-3.022619725,-2.631046188,-3.52214994,-2.592684502,-2.354714676,-4.0125033189999995,-3.1844883439999996,-0.6673508429999999,-3.4921770095825195,-4.395727157592773,-2.4554224014282227,-3.38409423828125,-3.1503243446350098 -3917,3917,A230F,0.003044142,0.018138504,-0.795527911,-2.128195162,-2.480813267,-0.019336381,0.024659935,-0.018571652,0.042794766,0.015549365,0.020727643,-0.504429139,-1.086626683,-2.177479247,-2.078911076,-2.501363277,-2.460263257,1.507483761,0.650746343,-11.126307699999998,-7.920529327000001,-9.904449295,-11.0034528,-13.911523,-12.89158408,-6.4552787910000005,-3.8655559810000004,-9.615095138549805,-9.886713027954102,-8.812539100646973,-11.196444511413574,-11.915203094482422 -3918,3918,A230I,0.034863112,0.001676746,0.042113699000000004,0.015709083000000002,-1.518781792,0.019535587,0.039806098,0.029920126000000002,0.005619140999999999,-0.061852423,0.065205914,0.013005243,0.071222155,0.010451374,0.020966791999999998,-1.5315428359999999,-1.5060207469999998,0.7248655540000001,1.321320016,-8.037424866,-7.436695922999999,-6.533652779,-7.785264503,-8.762618881,-9.668892242,-6.253143255,-3.764437635,-8.1349515914917,-8.836801528930664,-7.938603401184082,-9.769867897033691,-11.623983383178711 -3919,3919,A230H,-0.034737835,-0.579205569,-1.9604857009999999,-2.418624129,-2.800238208,0.021204162000000002,-0.037756676,-0.031718993,0.039513781,-0.44106243799999995,-0.7173487,-2.062859405,-1.8581119959999999,-2.211791695,-2.625456563,-2.535675725,-3.0648006910000003,1.10133539,-0.196933048,-11.88315462,-9.425069763,-11.60423812,-11.38770529,-13.46344165,-13.535318300000002,-7.730192914,-4.7787964789999995,-10.037982940673828,-10.055822372436523,-9.187087059020996,-10.663361549377441,-13.390559196472168 -3920,3920,A230K,-0.18703937,-1.195776298,-2.140636528,-2.264271566,-2.432901279,0.009118119000000001,-0.21879432199999999,-0.15528441699999998,0.078420479,-0.997536292,-1.394016304,-2.11640474,-2.1648683159999997,-2.198390241,-2.330152891,-2.522274271,-2.343528287,0.298042207,-0.642985108,-11.46725961,-10.14585313,-10.9941729,-11.76708222,-12.43277838,-11.99641143,-8.348859653,-6.875547631,-10.023082733154297,-10.226359367370605,-10.391448020935059,-10.297646522521973,-13.350743293762207 -3921,3921,A230M,0.00987137,0.025264624,-3.6700000000000004e-05,-0.009490555999999999,-1.560654907,-0.0053462530000000005,0.024464831,-0.004722092,0.036060762999999996,-0.034914851000000004,0.08544409900000001,-0.089611564,0.08953819800000001,-0.09241581900000001,0.073434707,-1.3789755259999998,-1.7423342869999998,1.013851818,1.361419387,-9.670725401,-8.979123085,-8.973285011,-10.04643431,-10.92424394,-9.430540657,-7.50578437,-6.029131173,-9.493824005126953,-9.275145530700684,-8.453206062316895,-10.113751411437988,-11.96237564086914 -3922,3922,A230L,-0.004442268,0.009531953000000001,0.029722899,-0.536704787,-1.8930656369999999,-0.040667257000000005,0.01469173,-0.023576265,0.003129215,-0.018531753,0.037595658,0.0013399010000000001,0.058105897000000004,-0.26970183600000003,-0.803707737,-2.02991305,-1.7562182240000002,1.31395131,1.325776552,-8.28114856,-6.228448631,-6.863342979,-8.58206649,-10.39068058,-9.341204117,-6.093341642,-3.850641903,-8.436985969543457,-8.068238258361816,-7.03468656539917,-8.984241485595703,-11.809945106506348 -3923,3923,A230N,0.065169214,-0.592148453,-1.93541351,-2.290927194,-2.741692622,-0.008096096,0.055185824,0.075152603,0.049316755999999996,-0.46623989,-0.7180570159999999,-2.2243101380000003,-1.646516881,-2.607325634,-1.974528754,-2.931209664,-2.55217558,0.501796989,-0.45374916200000004,-11.45653818,-10.63149962,-11.08081659,-11.70185131,-11.68044138,-12.188082000000001,-8.460426617000001,-6.642807821,-9.88301944732666,-9.534503936767578,-8.152470588684082,-10.768674850463867,-12.628961563110352 -3924,3924,A230Q,-0.023695522000000004,-0.10350028300000001,-1.6575347669999998,-2.053203827,-2.610909165,-0.020708925,-0.051239245999999995,0.0038482029999999997,0.052047864000000006,-0.071348852,-0.135651713,-1.700050487,-1.6150190469999999,-1.8489827769999998,-2.257424877,-2.649988062,-2.5718302680000003,0.7460731820000001,-0.000102915,-11.1032055,-9.470077972,-11.70854729,-11.01872617,-11.6031524,-11.71552365,-8.305837084,-6.47434758,-10.052806854248047,-9.286142349243164,-8.608929634094238,-11.134881019592285,-13.07430648803711 -3925,3925,A230P,-0.014726798000000001,-1.6946270890000001,-2.121499039,-2.362795216,-3.336932346,-0.007311351999999999,-0.013914923000000001,-0.015538673000000001,-0.079101488,-1.8319985369999998,-1.55725564,-2.1442271969999998,-2.09877088,-2.2596364540000002,-2.465953978,-2.981460492,-3.692404199,-0.477596666,-1.128753168,-10.04794205,-9.392321304,-10.02189403,-10.35748496,-10.32660672,-10.14140324,-7.7255789660000005,-5.688545746,-10.252946853637695,-11.583200454711914,-9.67994499206543,-13.107782363891602,-13.731042861938477 -3926,3926,A230S,-0.0030235970000000003,-0.016084651999999998,0.00952864,0.001800725,-1.721756113,-0.00892382,-0.012363881,0.006316688000000001,0.033354575,0.0047309529999999995,-0.036900257,-0.002006527,0.021063807,0.021827495,-0.018226046,-1.7286365190000001,-1.714875706,0.713462158,1.310446077,-6.392997942999999,-6.387666542000001,-6.076708595,-7.00126725,-6.447538292000001,-6.051809036,-6.592293261,-2.46894393,-6.74659538269043,-6.589430809020996,-5.8130059242248535,-6.714554309844971,-8.383106231689453 -3927,3927,A230R,-0.026987875,-0.102298681,-1.510833571,-2.145455837,-2.6212824130000003,-0.035452864,-0.042461235,-0.011514513999999998,0.010826753,-0.06857379799999999,-0.13602356300000001,-1.49444992,-1.527217222,-2.1014802280000002,-2.189431446,-2.772151744,-2.470413081,0.7911024390000001,0.04887163,-11.54919984,-9.209257164,-12.41247314,-11.36251881,-12.29312255,-12.46862756,-7.600294077,-5.607703599999999,-8.796255111694336,-8.990874290466309,-9.836812019348145,-8.55162239074707,-13.068957328796387 -3928,3928,A230T,-0.037679194,-0.020095778,-1.142326498,-2.040107479,-2.911652176,-0.021789298999999998,-0.045193905,-0.030164482000000003,0.001968283,-0.011047388,-0.029144167999999998,-1.0228320359999998,-1.261820959,-2.062756191,-2.017458766,-2.8985235830000002,-2.924780769,2.0964217609999998,0.813381625,-9.361114528,-8.350548759,-9.115197432999999,-10.38899005,-9.838944298,-9.111892097,-8.253697788,-6.430092654,-7.764275074005127,-7.520555019378662,-7.247404098510742,-8.10515022277832,-10.347009658813477 -3929,3929,A230W,0.087262094,0.044934558,-0.09520053699999999,-1.65611943,-2.481381369,-0.061574624,0.048870066,0.12565412199999998,0.017124752,-0.040404255,0.13027337,-0.125779621,-0.064621453,-1.557528166,-1.7547106940000001,-2.240434139,-2.722328599,1.047581533,0.7301790420000001,-12.60324454,-10.10696928,-12.48599938,-12.94141858,-13.58021128,-13.90162418,-7.4281568039999994,-4.646134273,-10.991743087768555,-11.407281875610352,-10.2008056640625,-12.105663299560547,-14.33249282836914 -3930,3930,A230V,-0.075575096,-0.012857571000000002,-0.005644093,-0.064019977,-1.723396046,-0.021461276,-0.068913097,-0.082237095,0.038540227999999996,-0.007933062,-0.01778208,-0.015905851000000002,0.004617665,0.035172998,-0.163212951,-1.782947499,-1.6638445919999998,0.716159621,1.307532352,-7.2174384279999995,-6.355203529,-5.98487616,-6.906607704,-8.383994987000001,-8.456509758,-6.179491962999999,-4.2439615580000005,-7.47498893737793,-7.390799045562744,-6.836960792541504,-7.88624906539917,-9.364477157592773 -3931,3931,A230Y,0.014798192,0.016326603999999998,-0.167497955,-2.33271403,-2.7143281089999998,0.033072957,0.045934892000000005,-0.016338508999999998,0.096786944,0.031352845,0.001300362,-0.121556739,-0.21343917,-1.92781811,-2.73760995,-2.8537621310000003,-2.574894086,0.8689848090000001,0.6699047370000001,-11.97813137,-8.509947296,-11.55051458,-11.53893936,-13.83476137,-14.45649422,-6.183387993999999,-2.796177016,-9.638334274291992,-10.066133499145508,-9.062238693237305,-11.43861198425293,-12.549988746643066 -3932,3932,D231A,0.02150478,-0.031308565,-0.018840684,0.025798237,-1.4331557590000001,-0.130587506,0.013137976,0.029871582999999997,-0.00188233,-0.003464338,-0.059152792,-0.008024237,-0.029657131,0.020495221,0.031101252000000003,-1.583391389,-1.282920128,0.68585368,1.3158599770000001,-12.52445417,-15.20094563,-10.58945024,-11.99042255,-12.43972858,-12.40172383,-7.876084272000001,-3.005386881,-11.119606018066406,-12.621183395385742,-10.932965278625488,-13.653951644897461,-13.189972877502441 -3933,3933,D231C,-0.023477007,-0.180688987,-0.039066814,-0.581795958,-1.725629241,-0.10330030400000001,-0.023537287999999996,-0.023416725,-0.01713389,-0.052729613,-0.30864836100000004,-0.050909473,-0.027224154,-0.5728061010000001,-0.590785814,-1.8396615369999998,-1.611596944,1.8371564740000002,1.4644759859999998,-14.36774703,-17.41568373,-12.83874007,-14.67206741,-14.8724793,-12.03976466,-8.124826844,-4.704388938,-12.233604431152344,-15.961790084838867,-12.000984191894531,-15.221880912780762,-15.269347190856934 -3934,3934,D231E,-0.054703638,-0.007488065,-0.02368147,-0.982891044,-2.05105119,-0.066203257,-0.021451001,-0.087956274,0.033970382,0.06764083900000001,-0.082616968,-0.001116839,-0.046246101,-0.737138582,-1.228643505,-1.64959004,-2.45251234,2.26292779,1.7462975180000002,-7.211638067999999,-10.33676988,-6.194371689,-4.920760361,-7.796875237,-6.80941317,-6.012169144,-3.3217758660000003,-5.599979400634766,-8.441364288330078,-6.894286155700684,-9.219992637634277,-6.9546709060668945 -3935,3935,D231G,-0.031729407,-0.069632209,-0.030286199,-0.9132807820000001,-1.758466787,-0.111285005,-0.016771211,-0.046687602,0.009171964,0.01083364,-0.15009805699999998,0.011554551000000001,-0.07212694900000001,-0.794679073,-1.03188249,-1.9171510680000001,-1.599782505,2.079027688,1.5313506140000002,-11.21315101,-13.44046407,-9.715814697,-10.49424036,-10.50487752,-11.91035838,-6.930495712999999,-2.008089853,-10.779377937316895,-11.014485359191895,-9.960702896118164,-11.998186111450195,-11.405435562133789 -3936,3936,D231F,-0.09247495900000001,-0.139342899,-0.076766997,-1.731017515,-2.555596064,-0.011034545,-0.083785061,-0.101164857,-0.040296723,-0.072148869,-0.20653692899999998,-0.06765242,-0.085881573,-1.904344325,-1.557690704,-2.7410750680000002,-2.370117059,0.8781032009999999,0.676465318,-17.91769814,-20.85068404,-15.508904500000002,-16.67570716,-19.95324709,-16.59994793,-8.311524423,-4.616693367,-14.567853927612305,-15.854206085205078,-13.895471572875977,-17.615203857421875,-16.497440338134766 -3937,3937,D231I,-0.034437642000000004,-0.064439119,-0.038726922999999996,-1.137602003,-1.741440104,-0.06807893200000001,-0.008821192,-0.060054092,-0.035785415,0.056551867,-0.18543010399999998,0.027466894,-0.104920739,-1.0280682509999999,-1.247135755,-1.9617090080000001,-1.521171199,2.318185927,1.62336739,-17.41571857,-21.46389272,-15.42449728,-15.98286625,-17.68820477,-16.51913185,-10.91672545,-9.471823037,-13.635470390319824,-15.835783004760742,-13.827503204345703,-16.86749839782715,-17.006587982177734 -3938,3938,D231H,-0.01461284,-0.12043495300000001,-0.053184487,-0.7180977040000001,-2.0697962519999997,-0.059624782,0.019788431000000002,-0.049014111,0.005902956,0.009621297,-0.25049120199999997,-0.018989685,-0.087379289,-0.6414144039999999,-0.7947810040000001,-2.038450391,-2.1011421130000003,1.7979625959999999,1.39336116,-10.408529,-13.89447209,-6.087576782,-10.72936848,-10.85985939,-10.47136825,-6.793893300000001,-0.09620016,-9.42840576171875,-12.953527450561523,-11.090027809143066,-13.152107238769531,-12.712841987609863 -3939,3939,D231K,-0.155447312,-0.129983221,-0.053511524000000005,-1.040931808,-2.095655881,-0.060421090999999996,-0.16789385699999998,-0.143000766,-0.035368265,-0.03077692,-0.22918952199999998,0.009376693,-0.116399741,-1.0317025359999998,-1.05016108,-1.935380069,-2.255931692,2.304627579,1.61597149,-17.00357504,-19.94821085,-16.50480152,-16.06061276,-16.78737693,-15.71687314,-10.95133296,-9.66088339,-13.678473472595215,-14.93568229675293,-14.34371566772461,-16.450891494750977,-15.969311714172363 -3940,3940,D231M,0.09687491699999999,-0.015080801999999999,0.063871564,-1.109071338,-2.377438798,-0.17296055600000002,0.129193136,0.064556697,-0.0032444109999999996,-0.010646899,-0.019514704,-0.002103125,0.129846253,-0.9260689540000001,-1.292073721,-2.628101124,-2.126776471,0.713532692,0.7585691659999999,-17.8868029,-21.40642545,-16.61448894,-16.68018628,-17.65567476,-17.07723906,-10.95133296,-9.66088339,-14.701042175292969,-15.485625267028809,-14.075084686279297,-17.350141525268555,-16.746423721313477 -3941,3941,D231L,-0.01955362,-0.067638102,-0.026758857999999996,-1.186572977,-1.942197894,-0.07194143900000001,-0.001533806,-0.037573433999999996,0.035970128,0.027952442,-0.163228646,-0.009591146,-0.04392657,-0.995185702,-1.3779602519999998,-2.022248144,-1.862147644,2.249805501,1.56493623,-16.71648513,-20.06024461,-16.06066321,-15.30705621,-16.96542526,-15.18903633,-9.074075826,-6.132198026,-13.171516418457031,-14.8294095993042,-13.755964279174805,-17.43931770324707,-14.869369506835938 -3942,3942,D231N,-0.094655512,-0.115059001,-0.079820668,-0.084419143,-2.118517766,-0.069757351,-0.04023423,-0.149076793,-0.067703729,-0.06645045299999999,-0.163667549,-0.023749651,-0.135891685,-0.055851824,-0.112986461,-1.844521122,-2.39251441,0.8431632440000001,1.310274663,-8.245499789,-10.20744124,-7.047991074,-7.8867011179999995,-8.583340446000001,-7.50202507,-5.640531499,-1.592780632,-8.774314880371094,-9.280323028564453,-8.635286331176758,-9.710271835327148,-10.39445686340332 -3943,3943,D231Q,0.009296067,-0.006101881,0.054436137999999995,0.04086683,-1.815948013,-0.11526935,-0.0016028079999999998,0.020194942,0.029981455,0.120006322,-0.132210083,0.11226831400000001,-0.0033960390000000004,0.073931046,0.007802613000000001,-1.673858614,-1.9580374109999998,0.7446176959999999,1.314767674,-13.81750317,-17.58630382,-11.99865932,-12.07512873,-14.5897247,-12.83769929,-8.08318493,-4.053220639,-11.20905590057373,-12.715583801269531,-11.252283096313477,-13.932280540466309,-14.103192329406738 -3944,3944,D231P,-0.025129627,-0.058151699999999994,-0.022263089,-1.3429517219999998,-2.134817462,-0.012285551,-0.008799594,-0.04145966,-0.024651687000000002,0.034701799,-0.151005199,0.015245792,-0.059771969,-1.146608492,-1.539294951,-2.155274534,-2.11436039,2.212031006,1.46114532,-16.61670105,-19.86104309,-14.49206679,-15.70908118,-16.49327897,-16.52803523,-10.95133296,-9.66088339,-15.683290481567383,-17.14632225036621,-14.604570388793945,-16.289352416992188,-17.089385986328125 -3945,3945,D231S,-0.044879811,-0.066896289,0.001676225,-0.253190316,-1.52339746,-0.066766269,-0.03292163,-0.056837991,0.028071235,0.044880156,-0.178672733,0.040801012000000005,-0.037448563,-0.13627676800000002,-0.370103864,-1.7447625569999998,-1.302032363,0.74019438,1.309956944,-11.09138589,-15.11667183,-9.022924629,-10.89742574,-10.26687474,-10.15303251,-6.231782626,-1.63233183,-9.810773849487305,-10.854439735412598,-9.844883918762207,-12.871938705444336,-13.456161499023438 -3946,3946,D231R,-0.029619827,-0.069495134,-0.037858882999999996,-1.593219528,-2.435618255,-0.011435605,-0.024178134,-0.035061519,0.013025219,0.013028031,-0.152018299,-0.002427939,-0.073289827,-1.442011022,-1.7444280330000002,-2.375651778,-2.4955847319999998,0.800768446,0.717246037,-15.3165288,-20.26387109,-11.12590406,-15.06020176,-15.41047896,-14.72218814,-7.937800905,-4.6524426619999995,-13.472000122070312,-15.157755851745605,-14.402486801147461,-16.940946578979492,-17.292537689208984 -3947,3947,D231T,-0.029162023999999998,-0.057831648,-0.025067172999999998,-0.905203042,-1.6948748759999999,-0.10030240800000001,-0.007965576,-0.050358472,-0.017628374,0.016527136,-0.132190432,0.008892259,-0.059026604,-0.691574679,-1.118831404,-1.783003084,-1.6067466680000002,2.058013686,1.5823195209999998,-12.88532298,-17.11983724,-11.07061105,-12.26683265,-12.17877994,-11.79055403,-7.530063402000001,-4.575727903,-10.951866149902344,-12.909296989440918,-11.847885131835938,-14.943992614746094,-15.08537483215332 -3948,3948,D231W,-0.01440188,-0.068342765,-0.079749356,-1.614615125,-2.6888924989999996,-0.012127568,0.003968834,-0.032772594,-0.01696164,-0.027823518999999998,-0.10886201,-0.132876326,-0.026622386,-1.6932786130000002,-1.5359516359999998,-2.7518581060000002,-2.6259268909999998,1.0177030059999999,0.710404665,-17.37247532,-19.63995239,-14.73155366,-16.65793226,-18.80848065,-17.02445762,-9.997386382,-7.224716754,-16.211694717407227,-17.569625854492188,-15.508968353271484,-18.001806259155273,-17.64178466796875 -3949,3949,D231V,-0.021635991,-0.056438037,-0.029804099,-1.418040477,-2.121734009,-0.130585275,-0.006528023000000001,-0.036743959,-0.027080272000000002,0.03748749,-0.150363564,0.050674658,-0.110282856,-1.2666895809999998,-1.5693913730000002,-2.091185868,-2.15228215,0.504656605,0.708746405,-15.541553400000002,-19.60045148,-12.72671576,-14.39001877,-15.89206888,-15.09851211,-9.388199098,-6.464888676,-11.988965034484863,-14.578841209411621,-12.045574188232422,-14.897628784179688,-13.62033748626709 -3950,3950,D231Y,-0.035408643999999996,-0.068099344,-0.044574367999999996,-1.340158007,-2.29251386,-0.00430867,-0.026289987,-0.044527301,0.061274864000000005,0.06692145099999999,-0.20312013899999998,0.0009328139999999999,-0.090081549,-1.183881637,-1.496434377,-2.212497907,-2.372529812,0.643764212,0.7244266070000001,-19.444442300000002,-22.94796281,-16.73211481,-18.12389132,-20.66852049,-18.74972209,-10.53155042,-8.194205584,-13.03654670715332,-14.418416023254395,-12.268030166625977,-14.576260566711426,-14.937968254089355 -3951,3951,K232A,0.073543302,-0.7660081470000001,-1.948488494,-2.0429487219999998,-2.767989534,-0.081793325,0.085738415,0.061348188,0.09191735599999999,-0.847752287,-0.6842640059999999,-2.0728870130000003,-1.824089974,-2.20120549,-1.884691954,-2.607547589,-2.9284314780000003,0.37525609600000004,-0.588503511,-7.690485501,-7.224586563,-8.135931503,-8.40393261,-7.467156043999999,-7.220820786,-6.774196565,-6.631834117,-11.845603942871094,-14.91943645477295,-12.680964469909668,-14.22276782989502,-9.759782791137695 -3952,3952,K232C,0.061430049,-0.771615624,-1.889817967,-2.322201298,-2.572818371,-0.075518355,0.112126741,0.010733356000000001,0.11668339,-0.8317005479999999,-0.7115307,-1.826168059,-1.953467875,-2.204364009,-2.440038587,-2.7867973669999997,-2.358839375,2.006635364,0.189572367,-10.69976607,-10.35565501,-11.10945867,-11.43157479,-10.78219494,-9.819946938,-8.744974317999999,-11.25201849,-10.912504196166992,-14.220592498779297,-9.56922435760498,-15.152524948120117,-11.313618659973145 -3953,3953,K232E,0.063966276,-1.3460314290000002,-2.109651813,-2.2181264030000003,-2.3411072230000003,-0.058302935,0.073244112,0.05468844,0.08506805099999999,-1.26314201,-1.4289208480000002,-1.96757491,-2.251728715,-2.220832124,-2.215420682,-2.326144227,-2.3560702190000002,-0.256491539,-0.782703596,-10.28574978,-10.14712431,-10.51823478,-10.96302866,-10.18988445,-9.610476707,-8.744974317999999,-11.25201849,-11.791019439697266,-14.378625869750977,-13.80388069152832,-14.64205265045166,-10.556550979614258 -3954,3954,K232D,0.064933144,-1.6036537659999999,-1.955319779,-2.563794369,-2.4253358169999997,0.015109717,0.10217797099999999,0.027688317,0.06923477900000001,-1.62089963,-1.5864079009999998,-2.27957504,-1.631064518,-2.356740994,-2.7708477439999997,-2.6381443559999997,-2.212527277,-0.602673123,-1.028445642,-10.73892904,-10.17700193,-11.29808409,-11.66785584,-10.70428182,-9.847421501,-8.744974317999999,-11.25201849,-13.424383163452148,-15.276942253112793,-13.281753540039062,-16.76259994506836,-13.559349060058594 -3955,3955,K232G,0.110905655,-1.235698896,-1.84441732,-2.238105482,-3.141039615,-0.083689184,0.11955945,0.102251859,0.058762953,-1.3311181779999999,-1.140279614,-1.834891627,-1.8539430119999998,-2.046756156,-2.429454808,-3.369552203,-2.9125270260000002,3.212951997,1.01462394,-10.65375057,-10.34063372,-10.9588671,-11.40688422,-10.66332354,-9.899044281,-8.744974317999999,-11.25201849,-11.170628547668457,-16.11353874206543,-11.587418556213379,-14.081067085266113,-10.772789001464844 -3956,3956,K232F,0.090013204,-1.7967385359999999,-2.17398081,-1.867803514,-2.317390591,-0.13214657,0.11831506300000001,0.061711345,-0.12503804400000001,-1.840972122,-1.752504949,-2.198617536,-2.149344084,-1.798662236,-1.9369447919999998,-2.557186852,-2.077594329,-0.343888897,-1.1379357,-11.50452171,-11.24553249,-12.23486275,-12.15371226,-11.74861314,-10.13988791,-8.744974317999999,-11.25201849,-13.531286239624023,-15.652458190917969,-13.374947547912598,-16.19024658203125,-13.301681518554688 -3957,3957,K232I,0.077505328,-1.37310446,-1.923740477,-2.293654441,-2.305710886,0.000307249,0.11898668,0.036023975,0.142530047,-1.303615553,-1.442593367,-2.184139712,-1.6633412419999998,-1.960275671,-2.62703321,-2.542709029,-2.0687127419999998,-0.12950747599999998,-0.796770082,-9.336810474,-9.552835533,-10.18445738,-9.892172112,-8.917527084,-8.137060257,-7.255308863,-7.194662168,-10.307960510253906,-14.005821228027344,-12.802051544189453,-13.900125503540039,-11.627596855163574 -3958,3958,K232H,0.029465005,-1.608602736,-2.025435634,-2.041564508,-2.819360412,-0.059017493,0.051965912999999996,0.006964097,0.008744913,-2.0025855569999997,-1.214619914,-2.059200976,-1.991670291,-2.13636693,-1.946762086,-3.0198302839999998,-2.61889054,-0.409005344,-1.105501505,-10.00958271,-10.09406387,-10.34819521,-10.47480766,-9.492454239,-9.638392601,-8.744974317999999,-11.25201849,-10.101045608520508,-12.056442260742188,-10.984915733337402,-12.444343566894531,-10.095288276672363 -3959,3959,K232M,0.08447579599999999,-1.725535054,-2.1652466969999997,-2.597630029,-2.459171476,-0.09996729,0.123313354,0.045638238,0.001279864,-1.844517402,-1.606552706,-2.3271015530000003,-2.003391841,-2.404267508,-2.790992549,-2.68567087,-2.232672081,-0.419713412,-1.091112429,-11.07135051,-10.91415833,-11.80742413,-11.86289611,-10.94793958,-9.824334389,-8.623810746,-10.34132175,-9.606136322021484,-13.49921703338623,-12.178102493286133,-13.418704986572266,-8.849810600280762 -3960,3960,K232L,0.006560852,-1.766377365,-2.153721333,-2.29908903,-3.171225127,-0.030077978,0.020051739,-0.006930036,-0.026144048,-2.090161363,-1.442593367,-1.8659501719999998,-2.441492493,-2.244146122,-2.354031937,-3.370647524,-2.9718027289999998,-0.543038417,-1.130320421,-9.43603049,-9.353606667000001,-10.31724256,-10.41808569,-9.01531192,-8.075905617,-7.365328747,-7.328917167999999,-10.60071086883545,-13.18733024597168,-11.925978660583496,-13.551785469055176,-11.016023635864258 -3961,3961,K232N,0.103629755,-0.925740171,-1.9306186980000002,-2.300532661,-2.312589106,-0.050263826,0.13543875800000002,0.071820752,0.181573083,-0.9176410770000001,-0.9338392640000001,-2.229529001,-1.6317083940000001,-2.306694955,-2.294370366,-2.588098317,-2.037079894,0.180452946,-0.620471113,-9.993179579,-9.381142319,-10.76366141,-10.76217239,-9.870181351,-9.188740433,-7.8607096510000005,-7.967380962000001,-9.257046699523926,-11.987513542175293,-10.639640808105469,-13.54952335357666,-9.9140625 -3962,3962,K232Q,0.10719943300000001,-1.392054498,-2.051432487,-2.094740194,-2.5839178940000003,-0.021317778,0.135332172,0.079066694,0.076115696,-1.548275708,-1.235833288,-1.993071297,-2.109793677,-2.070237252,-2.119243135,-2.8287618689999996,-2.339073918,-0.539286087,-0.994435159,-8.053912241,-7.838320564,-8.612745177999999,-8.542232491,-7.587720337,-7.688542633,-7.489686091,-7.325799114,-9.073800086975098,-10.794010162353516,-11.745158195495605,-11.909610748291016,-8.762195587158203 -3963,3963,K232P,0.015493356000000002,-1.7421605059999998,-2.108614335,-2.512195488,-3.126311925,0.031407025,0.048416615,-0.017429904,-0.07685439200000001,-1.989698644,-1.4946223669999998,-2.1935291930000003,-2.023699477,-2.6463587619999998,-2.378032214,-2.8308521110000004,-3.4217717380000003,-0.31520725,-1.135472472,-10.84425167,-10.48879866,-11.26675576,-11.56188834,-10.87240014,-10.03141547,-8.744974317999999,-11.25201849,-12.77102279663086,-17.33578872680664,-14.271450996398926,-17.75802993774414,-13.038810729980469 -3964,3964,K232S,0.105428878,-0.9898810459999999,-2.085286912,-2.144111735,-3.1104106889999996,-0.042518389000000004,0.137735641,0.073122114,0.068454789,-1.10474279,-0.8750193009999999,-2.378842152,-1.791731671,-2.103825589,-2.18439788,-3.33947146,-2.881349918,0.16681422,-0.69607527,-10.31687665,-9.820918045,-10.54060307,-10.99701662,-10.32670755,-9.899137955,-8.744974317999999,-11.25201849,-10.159492492675781,-13.480541229248047,-11.501002311706543,-13.732024192810059,-9.308842658996582 -3965,3965,K232R,0.064445581,-0.06086756,0.022663237000000003,-0.028213132000000002,-1.6105096319999999,0.026038111,0.094699232,0.034191928999999996,0.063558453,-0.17713307,0.05539795,-0.057326338,0.102652811,-0.053825149,-0.002601115,-1.880947867,-1.340071396,0.8714608779999999,1.31066779,-3.630975427,-3.535489922,-4.39150013,-3.6950628360000004,-2.80584742,-3.72697683,-3.5143688269999998,-2.9492701660000002,-4.185935020446777,-5.152163505554199,-4.189313888549805,-5.614717483520508,-2.059626579284668 -3966,3966,K232T,0.083565921,-0.906068049,-2.053486039,-2.134110555,-2.7482269919999998,-0.07974870099999999,0.08704581199999999,0.08008603,0.09292581300000001,-1.039174172,-0.7729619259999999,-2.252136791,-1.8548352869999998,-2.02827275,-2.239948359,-2.735644845,-2.760809138,0.20674585399999998,-0.663600732,-8.359550648999999,-7.844947609,-8.847665572999999,-8.970301376,-8.196747375,-7.938091309,-7.023709431,-7.448672964,-9.490310668945312,-12.527688980102539,-11.343117713928223,-13.755596160888672,-9.662233352661133 -3967,3967,K232W,0.001001222,-1.931671252,-2.3379095000000003,-2.113660606,-2.753353303,-0.01043169,0.02321227,-0.021209827,-0.096601726,-1.9600873280000002,-1.903255176,-1.7736646969999998,-2.902154302,-2.093868701,-2.13345251,-2.9773320539999997,-2.5293745519999997,-0.46540647,-1.132042495,-11.09683582,-10.97409312,-11.65188921,-11.75323758,-11.15150097,-9.953458214,-8.744974317999999,-11.25201849,-13.209783554077148,-15.757226943969727,-10.739745140075684,-15.198155403137207,-11.336821556091309 -3968,3968,K232V,0.025038074,-0.979286566,-2.206013843,-2.770017892,-2.719604968,-0.106735144,0.054507087999999995,-0.004430941,0.13573722,-1.067712206,-0.8908609259999999,-2.688599055,-1.72342863,-2.288643755,-3.251392028,-2.746138376,-2.69307156,-0.029632412,-0.688625712,-10.67735144,-10.74047121,-11.331510699999999,-11.25839244,-10.41691615,-9.639466721,-8.328212313,-9.200912815,-11.56534481048584,-14.423073768615723,-12.484909057617188,-13.840578079223633,-10.36799430847168 -3969,3969,K232Y,0.011627972,-1.7383571130000002,-1.87703876,-2.096437725,-2.4095241659999997,-0.039099912,0.017553965,0.005701979,-0.082547673,-2.076831586,-1.399882639,-2.258385741,-1.4956917790000002,-2.335551695,-1.857323755,-2.6169550569999998,-2.202093274,-0.371691475,-1.135335068,-11.20323113,-10.99004288,-12.02360719,-11.6689734,-11.46183777,-9.871694405,-8.744974317999999,-11.25201849,-13.676156044006348,-13.836134910583496,-12.99850845336914,-15.672027587890625,-12.229488372802734 -3970,3970,S233A,-0.0029132840000000004,-0.008919141,-0.029015492,-0.041034287,-1.023786368,-0.12300067699999999,-0.030137135,0.024310567,0.033343499,-0.016752081999999998,-0.001086199,-0.045282018,-0.012748965,-0.05352988,-0.028538692999999997,-0.870418499,-1.177154236,1.6019143409999999,1.6886808340000001,-4.7778343539999995,-3.966458855,-5.275302666,-4.187797821,-5.126283005,-5.333329422,-5.380325939,-3.2904786319999997,-10.322267532348633,-7.410714149475098,-9.999938011169434,-7.904890537261963,-9.186720848083496 -3971,3971,S233C,-0.056668422999999996,0.005768198,-0.205672685,-1.798893223,-1.777677999,-0.12082224800000001,-0.067321836,-0.04601501,0.042712274,-0.060262707,0.071799103,-0.082084666,-0.329260703,-1.862126635,-1.73565981,-2.2805929640000002,-1.274763034,0.912067208,0.682757946,-7.697366183,-6.312558243,-8.52914019,-6.966422661,-9.029300621,-7.649409202999999,-5.625619136,-3.1919391939999997,-10.150444030761719,-12.701896667480469,-10.249855041503906,-11.217928886413574,-11.917621612548828 -3972,3972,S233E,0.041641452999999995,-0.581458427,-1.934678895,-2.5894492909999998,-2.908854686,-0.142116999,0.041089017,0.042193889000000005,0.020777969,-0.662083385,-0.500833469,-1.987569432,-1.881788358,-2.764150868,-2.414747713,-3.085707184,-2.732002187,1.4738798180000001,-0.11873266699999999,-9.259359868999999,-9.211722496,-8.115876289,-9.231649307,-9.159769089,-10.57778217,-6.526460002,-4.020571731,-13.524738311767578,-12.205297470092773,-16.292461395263672,-13.065227508544922,-16.11724281311035 -3973,3973,S233D,-0.021052591000000002,-1.5742513319999998,-2.224201709,-2.407968079,-2.815419103,-0.173279584,-0.023664668,-0.018440513000000002,-0.07879575,-1.9601689999999998,-1.1883336629999999,-2.088374488,-2.3600289290000003,-2.643107176,-2.172828981,-2.964663491,-2.6661747140000003,-0.25781747899999996,-1.117005097,-11.1971903,-11.19294387,-11.96260175,-10.82149415,-10.03824068,-11.97067107,-7.8202582,-6.630980121,-12.00868034362793,-10.259679794311523,-14.970952987670898,-11.673707008361816,-14.841215133666992 -3974,3974,S233G,0.033394994,0.04291568,0.006717936999999999,0.008200309,-0.302187877,-0.120330205,0.013693091000000001,0.053096896,0.00267282,0.017095324,0.068736036,-0.016792961999999998,0.030228835,-0.011554552,0.027955169,-0.255220885,-0.349154869,1.538484432,2.155613264,-5.956546628,-6.022981917999999,-5.4462358779999995,-5.33016497,-6.3358261570000005,-6.647524216,-4.655795161,-3.163854358,-8.74752140045166,-9.904314041137695,-10.772229194641113,-6.9280195236206055,-10.783415794372559 -3975,3975,S233F,-0.09056416800000001,-0.7025668540000001,-2.0543633999999997,-2.598209422,-2.679054189,-0.048705548,-0.102155796,-0.07897254,0.007204959,-0.637244109,-0.7678895990000001,-2.087668892,-2.021057908,-2.165280325,-3.031138518,-2.7878666360000004,-2.570241742,0.76645888,-0.450964895,-11.27114156,-10.5059341,-12.41811362,-9.126551445,-11.25568946,-13.04941917,-6.76022354,-4.174097506,-12.127304077148438,-12.939830780029297,-15.57815170288086,-14.47023868560791,-14.633504867553711 -3976,3976,S233I,-0.016276483,-0.9273547940000001,-2.443502052,-2.3262384259999997,-2.5831744519999997,-0.10789686,-0.001957902,-0.030595063999999998,0.074180831,-1.029704337,-0.825005251,-2.464334853,-2.42266925,-2.064825031,-2.58765182,-2.8635026010000004,-2.302846302,0.256310146,-0.6629514320000001,-9.288046442,-8.630319527000001,-9.82844252,-9.341320076,-8.70461039,-9.935539696000001,-5.913011766,-2.449569311,-10.659103393554688,-9.140686988830566,-11.588052749633789,-12.100211143493652,-12.609295845031738 -3977,3977,S233H,0.021699277000000003,-0.188259168,-1.579530864,-2.022554204,-2.540929603,-0.157985318,0.039852796,0.003545758,-0.018153172,-0.18918477600000003,-0.18733356,-1.9986315019999998,-1.160430226,-1.900151676,-2.144956732,-2.6988292460000003,-2.38302996,0.894721186,-0.112637335,-9.935730826,-9.637008224,-9.996872726,-7.34124543,-9.94106942,-12.76245833,-6.602254827,-4.5167972,-13.479713439941406,-11.669234275817871,-13.195069313049316,-14.250118255615234,-14.695802688598633 -3978,3978,S233K,-0.094792722,-0.65658223,-2.377518646,-2.076266627,-2.429145416,-0.036082733,-0.073034849,-0.11655059400000001,0.10152942699999999,-0.516037423,-0.797127037,-2.411398778,-2.343638513,-2.011888956,-2.1406442980000002,-2.333445271,-2.524845561,0.282454551,-0.505821621,-11.02515488,-10.53993854,-11.8891048,-9.442303276,-10.47039078,-12.78403699,-8.461979646,-8.36621116,-13.429869651794434,-12.994596481323242,-14.345040321350098,-14.406636238098145,-14.021097183227539 -3979,3979,S233M,0.06756770599999999,0.056163505999999995,-1.515111712,-2.142525942,-2.495404731,-0.158393998,0.0511371,0.08399831099999999,0.063620542,0.061657562,0.05066945,-1.654819633,-1.3754037909999999,-2.510582316,-1.774469567,-2.531108636,-2.4597008259999997,0.299211971,-0.009781066,-11.17005204,-10.68482142,-11.58850202,-10.8575474,-10.89691033,-11.82247903,-7.521678822999999,-5.925439926,-11.95688247680664,-10.116963386535645,-13.287519454956055,-12.532502174377441,-11.87370491027832 -3980,3980,S233L,-0.047554248,-0.017874927,-1.527855187,-2.212910268,-2.653834687,-0.07045769,-0.044620847000000005,-0.050487647999999996,-0.009286563000000001,0.013255807,-0.049005661,-1.525889056,-1.529821317,-2.1733757959999997,-2.252444739,-2.561878901,-2.745790472,0.57748207,0.025442364,-11.58674515,-11.10211312,-12.85292254,-11.170969,-11.90112625,-10.90659482,-7.735812159,-5.925439926,-12.728206634521484,-9.328282356262207,-13.654176712036133,-12.90962028503418,-15.240787506103516 -3981,3981,S233N,-0.058782783,-0.167112867,-1.700682974,-2.27947458,-2.837440603,-0.065443339,-0.040372319,-0.077193247,0.01072854,-0.075063585,-0.259162148,-1.971814683,-1.429551265,-2.6514861069999998,-1.907463053,-2.9730424230000003,-2.701838782,0.311639603,-0.152816962,-7.445867848,-8.252419197,-7.84375074,-6.691624702,-5.923015648,-8.518528953999999,-5.627639628,-2.227014411,-10.313560485839844,-8.842906951904297,-9.352399826049805,-9.608400344848633,-9.86414909362793 -3982,3982,S233Q,0.033588952000000005,-0.023655387000000003,-1.54862578,-2.465455085,-2.395784855,-0.136311246,0.032653695,0.034524208,-0.0462634,-0.04812417,0.000813397,-1.7203977030000002,-1.376853857,-2.27513039,-2.655779779,-2.596686706,-2.194883003,0.513246757,-0.021692057999999997,-9.231069858,-9.089938888999999,-8.897967278,-7.668412712,-9.585470917,-10.91355949,-5.975568381,-2.316464156,-13.271700859069824,-10.912836074829102,-13.927689552307129,-14.16865348815918,-15.364006042480469 -3983,3983,S233P,0.015138462,0.031077404,-0.020468163,-0.5368836339999999,-1.8622693369999999,-0.123847399,-0.031721521,0.061998445,-0.0077061890000000004,-0.02706043,0.08921523699999999,-0.061832350999999994,0.020896026,-0.306131817,-0.767635451,-1.8477962209999998,-1.876742453,1.448092214,1.36903937,-5.499267377000001,-3.6259440460000003,-5.251581093,-3.9961682510000003,-7.095897742999999,-7.52674575,-3.976412237,-1.8061968730000002,-9.614144325256348,-10.144611358642578,-11.107306480407715,-9.693241119384766,-12.067405700683594 -3984,3984,S233R,-0.048622835,-0.357468884,-1.905316494,-2.3901128590000003,-3.0796995989999996,-0.0146084,-0.045116212,-0.052129457000000004,-0.003932202,-0.33301734,-0.381920427,-2.0736755419999997,-1.736957446,-2.276225711,-2.5040000069999997,-3.0749032819999997,-3.0844959160000003,0.9613668059999999,-0.188923128,-8.691011115,-9.177626465,-7.987243546,-6.983063133,-9.194494896,-10.11262753,-6.473013474,-4.504735051,-13.047554969787598,-12.634599685668945,-14.40520191192627,-13.586921691894531,-13.607735633850098 -3985,3985,S233T,0.041391567000000004,0.05976864900000001,-0.016953331999999998,0.008724631,-0.036772807000000005,0.18464142100000003,0.025467528,0.057315606,0.022945881,0.012518895,0.107018402,-0.049191958,0.015285295,-0.031135995,0.048585257,-0.043851792,-0.029693822,1.253544913,2.438382286,1.552480899,1.357504593,2.273680122,0.5094898379999999,1.5604938130000001,2.06123613,-0.399767727,2.0504422780000002,-0.5929946899414062,-0.9019975662231445,-2.4482898712158203,-2.462803840637207,-2.632272720336914 -3986,3986,S233W,-0.014515148,-0.024619921,-1.337217823,-2.283506596,-2.514866361,-0.062181935,-0.007492678000000001,-0.021537617000000002,0.025171943,-0.037336158,-0.011903684,-1.475969417,-1.198466228,-2.757700832,-1.809312359,-2.6021358930000003,-2.427596829,0.641043873,0.038702641,-12.46210702,-11.66486829,-13.05842155,-10.87946792,-12.3629908,-14.34478655,-8.461979646,-8.36621116,-14.594961166381836,-13.541616439819336,-15.98196792602539,-16.133037567138672,-15.95872688293457 -3987,3987,S233V,-0.003185508,-0.028056888,-1.435155577,-2.025274202,-2.8191033360000004,-0.11876076099999999,-0.007836195,0.001465179,0.002142543,-0.018939485,-0.037174291,-1.535043044,-1.335268109,-2.0598125080000003,-1.990735895,-3.381368824,-2.256837847,0.805654504,0.03887636,-8.449287708,-7.507466934,-9.504335724,-8.277966629,-7.610648277,-9.346020973,-5.818733606,-3.2552296239999996,-8.759782791137695,-8.116434097290039,-9.749560356140137,-10.992667198181152,-12.57064151763916 -3988,3988,S233Y,-0.007312254,-0.051809435,-1.595145808,-2.0962767319999998,-2.7167121219999997,-0.058815155,0.009462031999999999,-0.024086539,-0.074815302,0.021828524,-0.125447394,-1.9942754530000002,-1.196016163,-2.071886885,-2.1206665780000002,-2.8705644560000003,-2.562859788,0.335098279,-0.132583482,-11.76270984,-11.20507112,-13.12136493,-9.102277687,-10.89546326,-14.48937221,-6.593961966,-3.1953178330000003,-13.642837524414062,-13.394096374511719,-15.191837310791016,-14.847921371459961,-14.492300033569336 -3989,3989,G234A,0.02863772,-0.001013679,-0.014388006000000002,0.010276011,-0.451187719,-0.08219046599999999,-0.009846141999999999,0.067121582,-0.033045633,0.018556872,-0.02058423,0.0025200870000000003,-0.031296098,0.027390464,-0.0068384430000000005,-0.393264644,-0.509110793,1.00888511,1.619179944,-6.306129655,-6.258641097999999,-6.444292647999999,-6.2411720729999995,-6.455270515,-6.131271942000001,-6.729732471,-5.946089075,-10.119945526123047,-10.67061710357666,-13.733468055725098,-11.171098709106445,-12.563657760620117 -3990,3990,G234C,-0.000311783,-0.012054500000000001,-0.010929521999999999,-0.00472517,-1.561572545,-0.05531149,-0.011105364,0.010481799,-0.017877536,-0.00267501,-0.02143399,-0.009981653,-0.011877391000000001,0.054793874000000006,-0.06424421400000001,-1.703851245,-1.419293844,0.6025916570000001,1.307261529,-10.43842499,-10.6162741,-10.30271465,-10.42190092,-10.52473339,-10.32650192,-9.185551772,-11.79063775,-12.755242347717285,-13.549735069274902,-15.054628372192383,-12.690900802612305,-14.527048110961914 -3991,3991,G234E,-0.045315113,-1.058921167,-1.977628526,-2.138036628,-2.321554784,-0.02033968,-0.028896897,-0.061733328,0.034228411,-0.878398813,-1.2394435209999999,-1.946796501,-2.00846055,-1.748649069,-2.5274241859999997,-2.2051710780000002,-2.437938489,4.138613611,2.153247598,-10.39952753,-10.22866742,-10.42123166,-10.38530894,-10.66152987,-10.30089978,-9.177886845,-11.74813046,-12.38491439819336,-13.544756889343262,-16.1585750579834,-14.081099510192871,-14.743714332580566 -3992,3992,G234D,0.02294372,-1.588138586,-1.957331915,-2.38977404,-2.715611985,-0.081785481,0.017880819,0.028006621000000002,-0.10343415,-1.7036824069999998,-1.4725947640000001,-1.8726243919999999,-2.042039438,-1.866362487,-2.913185593,-2.658676597,-2.772547373,-0.272881496,-1.102085595,-9.770944043,-9.756021835,-9.948399704,-9.66662532,-9.822440353,-9.661233002000001,-8.137221204,-7.910816956000001,-12.40482234954834,-12.76026439666748,-14.926107406616211,-12.097030639648438,-13.387248039245605 -3993,3993,G234F,-0.013340527,-0.34360408299999995,-1.6797953540000001,-2.644369207,-2.606707788,-0.068570357,-0.020224715,-0.006456339,-0.009222664,-0.317924056,-0.36928411,-1.72990409,-1.629686617,-2.036906637,-3.2518317760000004,-3.1022220189999996,-2.111193556,1.409740339,0.071816329,-10.40542533,-10.51056316,-10.38879648,-10.30291407,-10.5271024,-10.29775055,-9.185551772,-11.79063775,-14.811553001403809,-16.250808715820312,-18.252899169921875,-14.536123275756836,-17.677440643310547 -3994,3994,G234I,0.017278238,-1.4382608369999998,-2.029519955,-2.9869735889999998,-2.648282175,0.017984054,0.049648539000000005,-0.015092063999999999,-0.11545232,-1.730005134,-1.14651654,-2.2211664140000003,-1.837873496,-2.7500177110000004,-3.2239294660000004,-2.514303098,-2.7822612510000004,-0.236967598,-1.1068479690000002,-10.41925751,-10.50464202,-10.47195818,-10.39855775,-10.54267944,-10.17845016,-9.185551772,-11.79063775,-15.129571914672852,-15.256460189819336,-19.343339920043945,-15.115327835083008,-18.121376037597656 -3995,3995,G234H,-0.071572495,-1.554517198,-1.957400961,-2.747627718,-3.010996295,0.030767332999999997,-0.06511952,-0.07802547,-0.06598407099999999,-1.572287375,-1.53674702,-2.0013007480000002,-1.9135011730000002,-2.7520007939999998,-2.7432546419999997,-3.118346172,-2.903646418,-0.110587603,-1.027089495,-10.41854019,-10.27740331,-10.36786759,-10.49305637,-10.58521826,-10.36915543,-9.185551772,-11.79063775,-14.815217971801758,-13.9808931350708,-17.5529727935791,-13.662471771240234,-16.91635513305664 -3996,3996,G234K,-0.042857617,-1.562354054,-2.6965190839999997,-2.509624587,-3.099599421,-0.031145079,-0.047132499,-0.038582735,-0.20298674,-1.7739610030000001,-1.350747105,-2.130423709,-3.262614459,-2.4040025000000003,-2.615246674,-3.247469133,-2.951729709,-0.11827156300000001,-1.152899961,-10.45424748,-10.51528107,-10.50200573,-10.39123663,-10.57730575,-10.28540823,-9.185551772,-11.79063775,-14.8948974609375,-13.881512641906738,-17.111970901489258,-14.548582077026367,-16.37181854248047 -3997,3997,G234M,0.024403547,0.06591409299999999,0.032693439,-0.12057512199999999,-2.433627533,-0.090968558,0.022368109,0.026438985,-0.0008810080000000001,0.05171755,0.080110636,0.047564330999999994,0.017822547,-0.073680226,-0.167470017,-2.2612114869999997,-2.606043578,0.793066976,1.27769163,-10.39744546,-10.31026997,-10.25030527,-10.48635746,-10.58432303,-10.35597157,-9.185551772,-11.79063775,-15.06138801574707,-16.129165649414062,-18.926708221435547,-14.514976501464844,-17.636104583740234 -3998,3998,G234L,-0.014686451000000001,-0.809411792,-2.0843616369999998,-2.35050456,-2.699437057,0.01814068,-0.006376118,-0.022996783,-0.040923087000000004,-0.778744711,-0.840078873,-2.325857396,-1.842865877,-2.326434915,-2.374574204,-3.044962812,-2.353911301,0.653942266,-0.542154185,-10.39558183,-10.46600101,-10.29216428,-10.35918356,-10.51693811,-10.34362217,-9.185551772,-11.79063775,-14.759170532226562,-15.34123420715332,-18.174978256225586,-14.658185958862305,-16.963041305541992 -3999,3999,G234N,-0.024967421,-0.609571955,-1.794934052,-2.569402284,-2.9832858589999995,0.027463486000000002,0.001740515,-0.051675357000000005,-0.04314524,-0.474555127,-0.744588782,-1.935753184,-1.65411492,-1.862544489,-3.2762600789999996,-3.131979854,-2.8345918639999996,1.171064495,-0.19067294,-10.41985786,-10.41463962,-10.36607552,-10.43760779,-10.53366042,-10.34730596,-9.185551772,-11.79063775,-13.447718620300293,-13.028030395507812,-15.60114860534668,-11.807384490966797,-14.493590354919434 -4000,4000,G234Q,-0.047122135999999995,-0.501619381,-2.015615443,-2.954174796,-2.478982746,0.002518225,-0.06968447700000001,-0.024559794,-0.035789286000000003,-0.412023635,-0.591215126,-2.293334679,-1.737896207,-2.52115598,-3.387193612,-2.489561349,-2.468404142,0.352765693,-0.474355865,-10.45483892,-10.46871574,-10.33889546,-10.56854253,-10.57324558,-10.32479527,-9.185551772,-11.79063775,-15.089216232299805,-14.011482238769531,-18.172611236572266,-14.962386131286621,-16.840356826782227 -4001,4001,G234P,0.002964446,-1.7622340380000001,-2.241413739,-2.550705022,-3.176723071,0.033272983,-0.045932057000000005,0.051860949,-0.205609947,-1.734257625,-1.79021045,-2.322328918,-2.16049856,-2.578178942,-2.523231102,-3.041434334,-3.3120118080000003,0.150036361,-1.131681049,-10.46165855,-10.47306409,-10.29586998,-10.58253554,-10.58524729,-10.37157586,-9.185551772,-11.79063775,-14.405274391174316,-15.391462326049805,-19.373577117919922,-17.57950210571289,-18.86842155456543 -4002,4002,G234S,0.018120186,0.028404317000000002,-0.015168879,0.028842321,-1.605763109,-0.077978752,-0.005472224,0.041712596,-0.045727847,0.02044486,0.036363772999999995,-0.02933032,-0.001007438,0.040513183,0.017171458,-1.6183135419999999,-1.593212675,0.748420535,1.318110479,-8.314960323,-8.306355858,-8.430583405,-8.257491631,-8.369066422000001,-8.211304298,-7.873708945,-7.54889086,-10.593681335449219,-11.07188606262207,-12.755385398864746,-9.956001281738281,-12.102944374084473 -4003,4003,G234R,-0.039126456000000004,-1.7141974569999998,-1.9797661659999999,-2.435319155,-2.901957822,-0.020290877,-0.040068666,-0.038184245,-0.177344135,-1.810133982,-1.6182609319999999,-1.927714599,-2.031817733,-2.440175479,-2.43046283,-3.061793362,-2.7421222810000003,0.065340873,-1.11885147,-10.42583389,-10.46886327,-10.38482246,-10.41553636,-10.6061175,-10.25382987,-9.154490617,-11.37314356,-12.407846450805664,-11.037689208984375,-14.824551582336426,-12.766135215759277,-14.33720874786377 -4004,4004,G234T,0.031195985,-1.081721343,-2.046177788,-2.333037854,-3.3294693669999997,-0.024475185,-0.017493792,0.079885762,0.0037230690000000003,-1.138875411,-1.024567274,-2.189344702,-1.9030108730000002,-2.0302213780000002,-2.63585433,-3.5105101089999997,-3.1484286239999997,0.40146603799999997,-0.691296483,-10.39642932,-10.40357899,-10.454572099999998,-10.48048015,-10.48601909,-10.15749628,-9.185551772,-11.79063775,-13.626506805419922,-13.536470413208008,-14.621834754943848,-12.514877319335938,-15.946651458740234 -4005,4005,G234W,0.015597611,-1.58791409,-2.1907881280000003,-2.204593901,-2.90549311,-0.00566266,0.025535132000000002,0.005660089,-0.170899374,-1.50366106,-1.672167119,-2.052814286,-2.328761969,-2.171491118,-2.237696684,-2.8388664919999997,-2.972119728,3.506104314,1.03420937,-10.45593116,-10.38541417,-10.53499925,-10.48162762,-10.54279255,-10.33482218,-9.185551772,-11.79063775,-13.859170913696289,-14.785257339477539,-15.915911674499512,-15.202409744262695,-15.914069175720215 -4006,4006,G234V,-0.02360701,-1.428594905,-1.9484004990000001,-2.411244085,-2.74767668,-0.014247851,-0.016472026,-0.030741993999999998,-0.07120542,-1.57919129,-1.277998519,-1.879538054,-2.017262943,-2.028178108,-2.7943100610000005,-2.2976134740000003,-3.1977398860000004,-0.642684232,-1.0946746520000001,-10.05566047,-10.12026865,-10.04816708,-10.02479716,-10.147808,-9.937261443999999,-8.867416257999999,-9.658166592,-12.37089729309082,-13.912877082824707,-17.02556037902832,-13.759016036987305,-14.818170547485352 -4007,4007,G234Y,-0.022137672,-0.15871307099999998,-1.642958163,-2.083699918,-2.784599127,-0.044783243,-0.037154547,-0.0071207959999999995,0.003970054000000001,-0.056540495,-0.260885646,-1.7417533630000002,-1.544162962,-1.839240895,-2.328158941,-2.6827075280000003,-2.886490725,0.6487923520000001,-0.019361066,-10.4410924,-10.46052343,-10.34562449,-10.50005337,-10.5792486,-10.32001213,-9.185551772,-11.79063775,-14.972597122192383,-15.964487075805664,-18.361225128173828,-14.45651626586914,-17.305776596069336 -4008,4008,A235C,-0.028105971,0.075852876,0.044039947999999995,-1.164923126,-2.08141988,-0.033883588,-0.001411115,-0.054800826,-0.027651207,0.119588018,0.032117732999999996,0.049613015,0.038466881,-0.994322867,-1.335523384,-1.642554446,-2.520285313,2.7317798289999997,2.08239639,-11.51819155,-9.462964745,-10.75461963,-10.25577422,-13.94590936,-13.17168981,-9.31986551,-3.8093664030000003,-10.474798202514648,-12.035602569580078,-12.846769332885742,-12.320035934448242,-13.823660850524902 -4009,4009,A235E,-0.011691018000000001,0.042006614000000005,-0.210975093,-1.491859997,-2.072320436,-0.115152184,0.065705145,-0.089087181,-0.028445197000000002,0.054009949,0.030003279,-0.130373288,-0.291576897,-1.445636858,-1.538083135,-2.330529066,-1.814111805,1.035496575,0.741344538,-11.6445981,-11.45084269,-9.773081894,-9.266075867,-13.85609575,-13.8768943,-8.520513183,-0.507266673,-8.716207504272461,-13.03880500793457,-12.453840255737305,-10.895711898803711,-12.715453147888184 -4010,4010,A235D,-0.09194124,0.042963840999999996,-0.98416695,-1.647866272,-2.115127014,-0.09226035099999999,-0.002120893,-0.181761587,-0.070047378,0.081630367,0.004297315,-0.789462329,-1.178871571,-1.7005463930000002,-1.5951861509999998,-2.471495248,-1.75875878,2.42351389,1.231798127,-11.72145004,-9.250252922,-10.55415818,-9.193722244,-16.13366814,-13.47544872,-8.021513392000001,-0.786022617,-8.769710540771484,-10.668593406677246,-11.85599136352539,-10.182188034057617,-13.380182266235352 -4011,4011,A235G,-0.015009855,0.041144591,-0.013612222,0.012796537,-0.19590627800000002,0.451028253,0.016294393,-0.046314102999999995,-0.07439092,0.059400771,0.02288841,-0.030114374,0.0028899309999999997,-0.029815038,0.055408112,-0.13023378900000002,-0.261578766,1.3465799569999999,2.22810876,-5.690745107000001,-4.832636856000001,-4.658793884,-4.18947393,-8.477126709,-6.2956941529999995,-5.915240371,-0.868158387,-5.71687650680542,-5.498639106750488,-8.417195320129395,-5.508235931396484,-7.1775970458984375 -4012,4012,A235F,-0.015331559,0.03564464,-0.908204115,-1.8197433859999999,-2.7314868010000004,-0.030949492999999998,0.019764146,-0.050427263,-0.055287866,0.047752844,0.023536436,-0.7476329709999999,-1.068775258,-1.586996245,-2.052490527,-2.5620650830000002,-2.900908518,2.284111694,1.167200295,-13.04182528,-11.16146475,-11.78339207,-10.82954465,-17.05699033,-14.37773458,-8.378154133999999,-3.5054297219999997,-9.9398832321167,-14.690353393554688,-11.771177291870117,-12.42890739440918,-14.486656188964844 -4013,4013,A235I,-0.021844542999999998,0.047786775999999996,-0.008456891999999999,-1.101936247,-1.6415324690000002,-0.091961225,0.01584725,-0.059536335,-0.054374899000000004,0.101570387,-0.005996835,-0.012151725,-0.004762058,-0.8227792359999999,-1.3810932569999999,-1.92694277,-1.3561221680000002,1.89680384,1.408201281,-11.36431353,-9.80933593,-10.22682204,-9.209547836,-13.16050863,-14.4153532,-8.853272695,-3.095008238,-9.840539932250977,-14.645663261413574,-10.968146324157715,-10.489967346191406,-15.07126235961914 -4014,4014,A235H,-0.050384711,0.029431236,-0.7784414479999999,-1.777158094,-2.923896147,-0.055735862000000004,0.021089311,-0.12185873300000001,-0.067214244,0.03487308,0.023989392000000002,-0.609849071,-0.947033825,-1.612279157,-1.942037031,-2.8303860430000003,-3.017406251,1.9520820719999998,0.964241472,-10.55989056,-9.558316498,-9.246012596,-7.980842041,-13.80185712,-12.21242457,-7.797509899,-3.218468263,-10.309385299682617,-13.670662879943848,-12.693431854248047,-12.097742080688477,-14.684396743774414 -4015,4015,A235K,-0.069329248,0.030898831,-0.772509265,-1.71371466,-2.4592008780000003,-0.12069147300000001,-0.019237598,-0.119420897,-0.07057700900000001,0.011259392,0.050538269000000004,-0.635551415,-0.909467114,-1.6756533830000002,-1.751775936,-2.650722221,-2.267679535,2.096379378,1.0222861909999998,-11.85066568,-11.42397823,-10.84323582,-10.72939079,-13.27336491,-12.98335863,-9.345151199999998,-5.171756881,-10.191707611083984,-14.759397506713867,-11.824810981750488,-12.687480926513672,-12.657279968261719 -4016,4016,A235M,-0.030704901,0.036352856,-0.016075435,0.008214469,-1.5088820219999999,-0.08181606799999999,0.006175024,-0.067584825,-0.09294853199999999,0.034139164,0.038566547,-0.04925603,0.01710516,-0.009641839000000001,0.026070776,-1.4758600530000001,-1.54190399,0.675564488,1.321332518,-9.151767949,-8.516134201,-9.270973152,-7.8625998610000005,-10.00388454,-10.10524799,-7.448986154,-2.583273555,-9.505325317382812,-13.637174606323242,-11.181973457336426,-10.545225143432617,-13.286288261413574 -4017,4017,A235L,-0.023488519,0.031821012,-0.019119743999999998,-0.006719813000000001,-1.561597794,-0.068352984,0.012323978000000001,-0.059301015,-0.083658216,0.056100563,0.00754146,-0.042617992,0.004378504,-0.002002899,-0.011436726000000001,-1.48139273,-1.6418028580000001,0.615855202,1.317431963,-10.81891654,-8.122883705,-10.28008495,-8.975374648999999,-12.79539559,-13.92084379,-7.788868083,-2.2944312069999997,-9.161959648132324,-13.749037742614746,-11.265902519226074,-10.514937400817871,-13.765735626220703 -4018,4018,A235N,-0.071027517,0.055404645999999995,-0.035691518,-0.18641672399999998,-1.827750319,-0.056930851,0.013257623,-0.155312657,-0.057936892000000004,0.051813490999999996,0.05899580000000001,-0.073910402,0.002527366,-0.130714193,-0.242119255,-1.713833386,-1.941667251,1.078612738,1.33740563,-8.918599149,-7.147688484,-8.812515633,-7.648098869,-11.361972999999999,-9.622719757,-6.915562287999999,-1.307764642,-8.261659622192383,-11.096776008605957,-10.535120010375977,-9.500102043151855,-11.664835929870605 -4019,4019,A235Q,-0.05467455,0.038408686000000004,-0.008853839,-0.650255203,-1.865425273,-0.121890295,0.009034012,-0.118383112,-0.031702992,0.05812324,0.018694131,-0.023035929,0.0053282519999999995,-0.42397479299999996,-0.8765356129999999,-1.6857246,-2.045125945,1.677709855,1.460300213,-9.946223592,-11.52090428,-8.530738273999999,-7.891485741,-11.38268351,-10.40530615,-7.260708673,-2.69286917,-9.517056465148926,-12.88652515411377,-12.428457260131836,-11.661197662353516,-13.031890869140625 -4020,4020,A235P,-0.019429378,-1.424658577,-1.693481054,-1.8103807719999998,-2.189950193,-0.055055467000000004,-0.002005437,-0.036853317999999996,-0.11274733699999999,-1.329484613,-1.51983254,-1.541576694,-1.845385413,-1.582594574,-2.03816697,-1.6726716469999998,-2.707228738,4.365761308,2.431379288,-12.32889045,-11.62655095,-11.11590831,-11.22559863,-14.50069403,-13.17570032,-11.38411299,-8.108516822,-11.794178009033203,-15.153300285339355,-11.95116901397705,-13.986444473266602,-15.759542465209961 -4021,4021,A235S,0.010401251,0.038181022,-0.003760595,0.003569439,-0.510609574,0.11061234,0.03386879,-0.013066288999999998,-0.080925361,0.057690879,0.018671164,-0.026744092,0.019222903,-0.051418938,0.058557815,-0.260929322,-0.760289825,1.476019049,2.043273514,-3.9993063980000003,-3.537286377,-3.784333702,-3.0925899119999998,-5.590388886,-3.991933113,-5.205697961,0.494013866,-4.322094917297363,-4.366576194763184,-6.886861324310303,-6.105778217315674,-7.768514156341553 -4022,4022,A235R,-0.0036256390000000004,0.039144301,-0.30902668899999997,-1.5428787830000001,-2.200683192,-0.047224800000000004,0.020704007,-0.027955284,-0.060735356,0.05183901,0.026449591,-0.225317994,-0.39273538399999997,-1.382464269,-1.703293296,-1.900306681,-2.501059703,3.269304576,2.326429437,-10.06662275,-9.126002013999999,-9.874828049,-8.569979431,-10.74576675,-12.0165375,-7.17399448,-2.422895161,-10.167689323425293,-10.333242416381836,-11.717565536499023,-12.119355201721191,-12.829132080078125 -4023,4023,A235T,0.007971499,0.020406668,-0.022568177999999998,-0.006645009,-1.25967584,0.156841218,-0.0078069640000000004,0.023749961,-0.042745024000000006,0.036592242000000004,0.004221094,-0.065863972,0.020727616,-0.05304959,0.039759572,-0.9831469909999999,-1.536204689,1.792915159,1.7907322469999998,-5.457007298,-5.945702766,-4.986124512,-5.456055022999999,-6.677488976,-4.219665215,-5.641632835,1.1195276840000001,-5.139211654663086,-9.354148864746094,-7.349620819091797,-6.7951765060424805,-9.522554397583008 -4024,4024,A235W,0.026176647,-0.209996459,-1.5504065930000002,-2.022610254,-2.532248478,-0.082580418,0.072118029,-0.019764736,-0.046250848,-0.0207075,-0.39928541799999995,-1.3986321119999998,-1.7021810730000002,-1.8446639630000001,-2.200556545,-2.428526174,-2.635970781,3.0806294189999996,1.554311802,-13.40710953,-9.876178841,-11.49637869,-11.84885735,-16.72697373,-17.08715905,-8.057920532999999,-1.371595226,-11.045899391174316,-12.91684627532959,-13.51129150390625,-14.445486068725586,-15.057312965393066 -4025,4025,A235V,-0.014581354,0.040542159,-0.011102751000000001,-0.179605979,-1.726128457,-0.089288014,0.036944443,-0.066107151,-0.07172793599999999,0.037455748999999997,0.043628568,-0.030854651,0.00864915,-0.101908174,-0.257303783,-1.432731318,-2.019525596,0.6723808609999999,1.3210154570000001,-10.10180878,-9.59604171,-9.467636208,-9.095258812,-11.76497532,-10.58513186,-9.201091555,-4.421113662,-8.584504127502441,-12.250365257263184,-9.638535499572754,-9.184730529785156,-11.967819213867188 -4026,4026,A235Y,-0.06511365599999999,0.008960559,-0.400849082,-1.6276882719999999,-2.9049267619999997,-0.072336026,0.010123797,-0.140351108,-0.043185095,0.01131384,0.006607278,-0.313201916,-0.48849624799999997,-1.572147124,-1.6832294190000001,-3.0912840060000004,-2.7185695169999997,1.4172534469999998,0.7893134079999999,-13.31970662,-11.3285424,-11.78512462,-10.7929362,-16.3608126,-16.33111727,-8.042284817999999,-3.293510926,-10.276413917541504,-13.785406112670898,-12.266221046447754,-12.851409912109375,-14.388556480407715 -4027,4027,G236A,0.054920385,-0.00786816,0.0041942970000000005,0.042776524,-0.236250409,1.4045676809999998,0.04638718,0.063453589,-0.045242464,-0.009638205,-0.006098115,0.004062463,0.00432613,0.040932679,0.04462036900000001,-0.130637802,-0.341863016,1.141619583,2.234523073,-5.9904846570000005,-6.740699188,-6.198597778,-5.525183105,-6.328148323,-5.159794891000001,-5.378278074,-2.351335558,-7.578941345214844,-5.431602478027344,-6.007373332977295,-5.831399917602539,-9.421562194824219 -4028,4028,G236C,0.016168896000000002,-0.035612002999999996,-0.000123516,-1.557431733,-2.686057566,0.781797972,0.018799879,0.013537913,-0.085019102,-0.084841007,0.013617001,0.002486103,-0.002733135,-1.286967162,-1.8278963030000002,-2.519368437,-2.852746694,0.75016782,0.725861924,-8.433650706,-9.119224792,-7.165339417,-8.499766029,-6.513357468,-10.87056583,-6.06093129,-3.699459731,-9.395621299743652,-10.518268585205078,-12.246952056884766,-11.0918550491333,-11.471165657043457 -4029,4029,G236E,-0.025605592000000003,0.053935217,-0.342622748,-1.761089106,-2.712110453,0.9481715940000001,-0.014127708999999999,-0.037083474,0.001462491,0.072443761,0.035426672,-0.089704946,-0.59554055,-1.42759753,-2.0945806819999997,-2.643608389,-2.780612516,0.883967682,0.726753262,-11.07687134,-12.66613824,-9.15596666,-9.795286308,-14.64418588,-9.122779593999999,-8.251645,-3.427835284,-10.754144668579102,-11.215627670288086,-12.10456657409668,-12.82138442993164,-13.177324295043945 -4030,4030,G236D,0.052633837,-0.00289657,-0.010938381,-0.728995961,-2.1808833,0.660405004,0.033892086,0.071375587,-0.027654295,-0.02923162,0.02343848,-0.055345889,0.033469128,-0.528218019,-0.929773902,-2.05842032,-2.303346279,1.596939691,1.340400937,-10.40868176,-13.51851229,-9.3929832,-7.689338188,-12.96562212,-8.476953011,-5.888396052,-3.2705552239999998,-9.615323066711426,-9.509462356567383,-10.584287643432617,-11.383244514465332,-12.07856559753418 -4031,4031,G236F,0.023655225,-0.17676446899999998,-1.514488812,-2.033961992,-2.9557703269999998,-0.12059494300000001,0.038494357,0.008816092,-0.052371447,-0.053879175999999994,-0.299649762,-1.5772502430000002,-1.451727381,-1.7842791080000002,-2.283644876,-2.585316619,-3.3262240339999996,4.1752142999999995,2.531264474,-13.76695112,-15.03014908,-11.82020096,-11.61685472,-15.12153581,-15.24601501,-6.885241271,-3.1562422189999997,-13.594083786010742,-12.67038631439209,-13.166398048400879,-13.794486999511719,-16.152477264404297 -4032,4032,G236I,0.05669484,0.013980635,-1.274034575,-1.817826323,-2.9569191089999998,-0.043943384,0.06823079,0.045158889,-0.032207638,-0.020694114,0.048655382999999996,-1.067759695,-1.4803094540000001,-1.8883283690000001,-1.7473242759999998,-2.592455867,-3.3213823510000005,2.503887582,1.134896822,-12.08687547,-14.26152103,-9.609776604,-11.97545664,-13.4790716,-11.10855147,-5.750241114,-1.5413350719999999,-13.140585899353027,-12.030141830444336,-13.724637985229492,-12.842339515686035,-15.81728744506836 -4033,4033,G236H,0.04394105,-0.007799824,-0.560650643,-1.969638716,-1.9887343830000002,-0.02552734,0.010353933000000001,0.077528167,-0.112005342,-0.054633715,0.039034067,-0.23754148,-0.883759805,-1.838354394,-2.100923038,-2.241451896,-1.73601687,1.300201944,0.72294033,-14.04521766,-16.20570544,-13.49273473,-10.88203595,-15.84487952,-13.80073266,-9.574363502,-7.314840247999999,-13.989450454711914,-11.244208335876465,-12.59920883178711,-15.226189613342285,-15.29035472869873 -4034,4034,G236K,-0.0503228,-0.5170904470000001,-1.928514672,-2.5483175769999997,-2.771155907,-0.10223396300000001,-0.116282401,0.015636801000000002,-0.021413802000000003,-0.227564365,-0.806616529,-2.198093463,-1.65893588,-2.2589942919999997,-2.837640861,-2.3610617990000002,-3.181250015,0.623919979,-0.30173249399999996,-11.05469652,-13.38614217,-9.933208183,-8.818348557,-15.03904633,-8.09673735,-7.656752772999999,-4.512334836,-13.433807373046875,-12.145415306091309,-13.169543266296387,-14.796314239501953,-15.48346996307373 -4035,4035,G236M,0.076077303,0.02587162,-1.192713259,-2.152759463,-2.7646734189999997,0.036579289,0.06992599299999999,0.082228612,-0.057617519000000006,0.038085311000000004,0.013657928,-1.0454833000000001,-1.339943217,-1.805354134,-2.500164792,-2.384542895,-3.144803942,2.863739462,1.49016366,-14.21205618,-16.05875796,-10.47703264,-13.76903478,-16.13063683,-14.6248187,-7.122014412,-3.8688708789999997,-12.901975631713867,-12.754093170166016,-12.96589183807373,-12.694323539733887,-15.698312759399414 -4036,4036,G236L,0.0035140040000000003,-0.31614280899999997,-1.651235634,-2.096764423,-2.99387687,-0.095184697,0.003738939,0.0032890690000000004,-0.045340653,-0.058677208,-0.57360841,-1.554426267,-1.748045001,-1.86199943,-2.331529416,-2.291425871,-3.6963278689999997,3.79842667,2.192439685,-13.13020982,-13.29615464,-9.166885292,-12.9829286,-15.89587486,-14.30920568,-6.114824407,-0.74215118,-12.145442962646484,-12.764379501342773,-12.024405479431152,-12.566885948181152,-14.557733535766602 -4037,4037,G236N,0.084387894,0.028674557000000003,0.002736551,0.03683882,-1.2087691790000001,1.4338252059999999,0.090863136,0.077912651,-0.0013889629999999998,-0.063372329,0.120721442,-0.008056802,0.013529903000000001,-0.0025804079999999997,0.076258047,-1.154093974,-1.263444383,0.969611214,1.369024506,-8.81307034,-11.81098616,-9.346120369,-4.454513618,-11.99545193,-6.458279625,-5.109286281,-2.968751407,-10.120509147644043,-7.154273509979248,-9.386913299560547,-11.2503080368042,-10.727834701538086 -4038,4038,G236Q,0.038087266,-0.027078625,-0.807437958,-1.76236379,-3.07324775,0.415829072,0.069515338,0.006659194,-0.061340516,-0.01647346,-0.037683789,-0.489180799,-1.125695117,-1.583505384,-1.941222195,-2.685572891,-3.460922608,1.831040459,0.9301763279999999,-11.01859875,-11.81768144,-9.766072563,-9.569935776,-14.43538501,-9.503918945,-6.895352105,-2.8266956110000003,-12.08719539642334,-11.897468566894531,-11.838427543640137,-14.137861251831055,-14.008953094482422 -4039,4039,G236P,0.040972019,-1.76898324,-2.151777122,-2.287503711,-3.063569707,-0.122100721,0.028043194,0.053900843,-0.129893171,-1.9019066000000002,-1.636059879,-2.2628412890000003,-2.040712955,-2.365134803,-2.209872618,-2.512959801,-3.614179612,-0.303889358,-1.158243746,-9.695256825,-7.400000641,-8.576845589,-9.982379929,-11.06167657,-11.45538139,-6.376942011000001,-4.3021708080000005,-12.316100120544434,-11.490077018737793,-12.566465377807617,-14.464975357055664,-18.13525390625 -4040,4040,G236S,0.050618200999999995,0.010690989,-0.01785845,0.003626732,-1.467128934,1.4272528919999998,0.040005473,0.061230928,-0.029272727999999998,-0.0017380770000000002,0.023120055,-0.016493109,-0.01922379,-0.012432857,0.019686321,-1.246408235,-1.6878496330000001,1.299185752,1.4449782430000002,-5.44332608,-6.441233025,-6.566121033,-3.66125499,-5.999168312,-4.548853043,-4.005352312,-3.120877891,-7.161515235900879,-6.762178421020508,-5.703176021575928,-7.741616249084473,-9.993837356567383 -4041,4041,G236R,-0.014763252,-0.622823398,-1.836555433,-2.0496448330000003,-2.615893721,-0.056197104000000005,-0.023457015,-0.006069489,-0.060476969000000005,-0.33312123,-0.912525565,-1.797717131,-1.875393735,-1.9835566969999998,-2.115732969,-2.5627454590000003,-2.669041982,1.5362142,0.014015193,-11.92877893,-14.04647554,-10.93394056,-10.48732816,-13.38381291,-10.79233746,-7.9088425760000005,-6.052350264,-12.218830108642578,-10.231689453125,-12.159667015075684,-13.9827241897583,-13.103593826293945 -4042,4042,G236T,-0.001385194,-0.006117900999999999,0.001107483,-0.03642424,-1.740199749,1.23885317,-0.010713826999999999,0.007943439,-0.021668358,-0.02697369,0.014737888000000001,-0.011837569,0.014052533999999998,0.006286655,-0.07913513400000001,-1.5291017830000002,-1.951297714,1.052727119,1.330378607,-8.989255266,-9.760221771,-8.335565483,-7.561612602,-10.44659397,-8.842282501,-6.672785381000001,-4.5949103330000005,-9.493619918823242,-8.960801124572754,-9.93010425567627,-10.75897216796875,-13.911612510681152 -4043,4043,G236W,-0.00414746,-0.36047249600000003,-1.5883721919999998,-2.078936274,-2.740907806,-0.083322945,0.0008197580000000001,-0.009114677,-0.025167382999999998,-0.13143757,-0.589507421,-1.499123459,-1.677620924,-2.134055556,-2.023816992,-2.838183054,-2.643632558,0.964214948,0.061939857,-13.52776256,-13.89034081,-13.049819900000001,-12.00755156,-15.06000651,-13.63109402,-6.695678947999999,-4.416799003,-14.62309741973877,-12.761489868164062,-13.52328109741211,-15.420604705810547,-15.410163879394531 -4044,4044,G236V,-0.006881796999999999,-0.037952103,-1.285161504,-2.2914729769999997,-3.008813615,0.004531591,-0.004125752,-0.009637841,-0.046413915,0.03258214,-0.108486346,-1.2028923459999998,-1.3674306619999999,-2.485641925,-2.097304028,-3.0648306869999997,-2.9527965430000003,1.826665002,0.476396305,-11.52327332,-14.02641759,-10.52207693,-11.19530595,-11.29552094,-10.577045199999999,-6.462964239,-1.995438169,-11.353181838989258,-10.138952255249023,-12.548938751220703,-12.051277160644531,-13.940274238586426 -4045,4045,G236Y,0.004943683,-0.231872153,-1.774563795,-2.126810099,-2.977284682,-0.048244934,0.033344442,-0.023457076,-0.002219374,-0.029576826,-0.43416747899999997,-1.5576177709999999,-1.9915098180000002,-1.986495385,-2.267124812,-2.565684147,-3.3888852160000003,2.812348987,1.212091853,-14.01606773,-15.86405241,-13.79184651,-10.75937568,-14.81475333,-14.85031072,-6.704260027999999,-4.977186618,-14.627446174621582,-12.426825523376465,-13.272064208984375,-14.701337814331055,-15.623610496520996 -4046,4046,E237A,0.021780287000000002,0.013122682,0.002696695,0.010723965,0.004358278,0.329409481,0.012706366,0.030854207999999998,0.037742492,-0.004461775,0.030707138999999998,0.026978215,-0.021584826,0.011727353000000001,0.009720577,-0.0007759160000000001,0.009492471,1.190274632,2.681530754,-1.7230000490000001,-1.042876999,-2.188456757,-2.101392014,-1.735931923,-1.5463425519999998,-2.036443416,0.387706604,-5.127357482910156,-6.946106910705566,-2.881275177001953,-3.5621745586395264,-3.5539822578430176 -4047,4047,E237C,0.051736014000000004,0.04806995,0.051035383,0.052475840999999995,0.011073096000000001,-0.01764537,0.058828335,0.044643693,0.015383121000000001,0.060040357999999995,0.036099542000000005,0.095683344,0.006387421999999999,0.046285667999999995,0.058666012999999996,0.003102715,0.019043477,1.265153065,2.758888417,-7.751953905,-7.498514572,-8.854867561,-8.580556892,-8.264492996,-5.561337502000001,-6.385090407000001,-3.7830394060000003,-11.371973991394043,-12.501799583435059,-9.119833946228027,-10.586139678955078,-10.670265197753906 -4048,4048,E237D,0.129920762,0.047613035,0.034996803,0.030155652999999998,0.066875465,0.04395571,0.135514281,0.124327243,0.00324197,-0.000536259,0.09576232800000001,-0.013446969,0.083440574,-0.014215956,0.074527261,-0.017419855,0.151170784,1.189624685,2.483117129,-1.008859439,-0.504138275,-0.9269142229999999,-1.0166974640000002,-1.816116844,-0.7804303890000001,-1.644379766,1.175356731,-3.341008424758911,-4.541986465454102,-2.263965606689453,-2.408843517303467,-4.843806743621826 -4049,4049,E237G,0.037270041000000004,0.020322382,0.005767481999999999,0.02180569,0.008001971,0.7673142820000001,0.03854652,0.035993561,0.005855366,0.018844458999999997,0.021800305,0.024400152999999997,-0.01286519,0.011386368999999999,0.03222501,0.007929292,0.00807465,1.0872725429999999,2.8251325210000005,-0.63343844,-0.685592117,-1.5292422490000002,-0.112332275,-1.308316971,0.468291412,-0.889596079,1.252001601,-3.131970167160034,-4.956923007965088,-0.9126076698303223,-0.041794776916503906,-1.2605094909667969 -4050,4050,E237F,0.153724933,0.049986438,-0.02540932,0.055841655999999996,0.022973874,-0.066171618,0.179112722,0.12833714300000001,0.047476287,0.004503379,0.09546949699999999,-0.004950031,-0.045868609000000005,-0.0021271999999999997,0.113810511,-0.035525883,0.08147363099999999,1.304347324,2.554738565,-7.826209392999999,-7.786741248999999,-9.531871574,-7.634156699999999,-7.511129974,-6.667147469,-3.923115408,-1.488799733,-9.075261116027832,-11.275557518005371,-7.256970405578613,-8.722940444946289,-6.758841037750244 -4051,4051,E237I,0.039466995,0.000513951,-0.022627027,0.00763736,-0.278604064,0.213064549,0.041194267,0.037739722999999996,0.028992881,-0.027712941,0.028740842000000003,-0.02247539,-0.022778662999999998,-0.047730055,0.063004775,-0.247763756,-0.30944437199999997,1.085590718,1.7841169559999999,-8.474566351,-6.287865906,-10.72831259,-9.400867172,-8.503458237,-7.45232785,-4.555756074,-0.245710896,-8.606592178344727,-9.451019287109375,-6.934105396270752,-7.79703426361084,-6.651734828948975 -4052,4052,E237H,0.011325577,0.055101765999999996,0.007777483000000001,0.033230232,0.017693319,0.079610919,0.0014414929999999999,0.02120966,0.006749528,0.066766089,0.043437442,0.050909533,-0.035354567999999996,0.060711483,0.00574898,0.040326054,-0.004939415999999999,1.1133497190000001,2.638047589,-4.984220873,-4.724647827,-5.518680847000001,-4.722360977,-5.429035751,-4.52637896,-4.106831979,-1.6177099869999998,-8.013652801513672,-10.115198135375977,-6.817974090576172,-8.122081756591797,-7.198238849639893 -4053,4053,E237K,-0.008818906,0.020584535,0.008749543,0.00207233,0.020351337,0.024162714,-0.015203081,-0.00243473,0.014449873,0.019235198999999998,0.02193387,0.052596433,-0.035097348,0.01643458,-0.01228992,0.027386275,0.013316399,1.192568025,2.796023765,-1.8804953919999998,-1.283476852,-1.420520531,-2.385920547,-2.256177727,-2.0563813019999997,-1.708415899,-1.12334336,-6.723128318786621,-7.71699333190918,-6.974329471588135,-6.631309509277344,-5.44495153427124 -4054,4054,E237M,-0.024339267,-0.001607612,-0.027492539,-0.005991746,-0.01660617,0.044449022000000005,-0.012518659,-0.036159875,0.035613181,-0.04898579,0.045770566,0.028665851000000003,-0.083650928,-0.029932472999999998,0.017948981,0.002606818,-0.035819158,1.267990563,2.835683017,-7.3392546329999995,-6.645161407000001,-7.990439049,-8.980987472999999,-6.923070572,-6.156614662000001,-4.405676593,-1.120437912,-9.17976188659668,-9.471962928771973,-6.6870880126953125,-7.36332893371582,-7.2041335105896 -4055,4055,E237L,0.022531059,-0.003476843,-0.010275342,0.025241642,0.02178387,-0.016616726999999998,0.041051223,0.004010894,0.015236013999999999,-0.0038180709999999997,-0.003135615,0.037017276,-0.05756796,0.023981534,0.02650175,0.024727497,0.018840242,1.195692299,2.706288723,-7.630595923,-6.348345527999999,-8.29258593,-9.646323921,-8.501368141,-5.364356094,-4.219657555,0.291238382,-7.2175092697143555,-8.694252014160156,-5.425127983093262,-6.411876678466797,-6.305868148803711 -4056,4056,E237N,0.062287568,0.027558955,0.01971382,0.026362486,0.028963159,0.213054033,0.08783974,0.036735396000000003,0.021612082999999997,0.041625729,0.01349218,0.034456916000000004,0.004970723,0.002279997,0.050444974000000004,0.0013333370000000002,0.05659298,1.13577818,2.5461157880000003,-1.539078392,-0.962950317,-1.5710060730000002,-1.57174353,-1.974481613,-1.615210426,-2.5268971330000003,0.044551579,-5.336175918579102,-7.347254753112793,-3.344817638397217,-4.342668533325195,-4.080183982849121 -4057,4057,E237Q,0.055866474000000006,0.013583835,0.027046884,0.049372207,0.031464553,-0.098277772,0.073977456,0.037755491,-0.031869808,0.026299358,0.0008683110000000001,0.06533710599999999,-0.011243339,0.053420194000000004,0.04532422,0.052932038,0.009997068000000001,1.15149873,2.8459302589999997,-2.9143511369999997,-2.552410797,-3.0521844789999997,-2.707819725,-2.8996105119999998,-3.3597301710000003,-4.331324636000001,-0.91444466,-6.035417079925537,-7.421958923339844,-5.166451930999756,-5.963239669799805,-4.8873748779296875 -4058,4058,E237P,0.064673047,0.016898097,0.01298529,0.045290303,0.01334188,0.879597561,0.06112211099999999,0.068223983,0.002832723,-0.014535569,0.048331762,0.014018847,0.011951733,-0.008556985999999999,0.099137592,-0.007948202,0.034631962,1.190206942,2.541524194,-5.711589749,-3.336375763,-7.32109021,-6.720326889,-5.469748267999999,-5.710407616,-3.498589167,0.449849744,-5.559365272521973,-10.600945472717285,-4.927679538726807,-5.697056770324707,-6.285775184631348 -4059,4059,E237S,0.044308005,0.012462466,-0.024124835,-0.005290478,-0.047764577999999995,0.325162794,0.033265859,0.05535015,0.001883178,0.024343557000000002,0.0005813740000000001,-0.008667625,-0.039582044,-0.019850134,0.009269179,-0.012465406000000002,-0.083063749,1.191086666,2.517326855,-2.1073248280000003,-1.815759651,-2.125610115,-2.863621536,-3.10025209,-0.631380745,-2.502537181,0.606592479,-4.6122026443481445,-6.753887176513672,-1.4997891187667847,-4.149130821228027,-2.6924924850463867 -4060,4060,E237R,0.045530611,0.040534671,0.03014494,0.030740913999999998,0.028908156,0.106256456,0.05354264,0.037518581,-0.009808532,0.023388678,0.057680663,0.043868082,0.016421797,0.014723341000000001,0.046758487,0.005038931,0.05277738,1.235410105,2.707092308,-3.3653319760000002,-2.4669711690000002,-4.167800461000001,-3.3526413880000003,-3.713146545,-3.126100319,-2.301821628,0.063660658,-7.048914909362793,-8.48853588104248,-7.483720302581787,-7.513629913330078,-5.66402530670166 -4061,4061,E237T,0.022768817,0.033842372,-0.007626198000000001,0.019304303999999998,-0.086835761,0.42438368200000004,0.023216422999999996,0.02232121,0.002117415,0.040711317999999996,0.026973425,0.03670994,-0.051962335,0.011794448,0.026814159,-0.043992692,-0.12967883,1.35872297,2.542566953,-4.79134041,-3.460786819,-5.216501785,-6.679636238,-5.567997635,-3.031779572,-3.03943117,0.23675860199999998,-6.301420211791992,-7.565990924835205,-4.0280585289001465,-5.891366004943848,-5.528197765350342 -4062,4062,E237W,0.000430592,0.007982886,0.00551169,0.040974098,-0.023706336,0.036092106,-0.0026470929999999997,0.003508277,0.028590942999999997,0.041132231,-0.025166459,0.037607092,-0.026583713,0.060072903,0.021875292,-0.023614722999999997,-0.023797948,1.148176074,2.62011901,-8.419979745,-7.794738799999999,-10.06187313,-8.679413231,-8.243644295,-7.3202292710000005,-4.769548245,-2.2497890369999998,-10.538238525390625,-10.985393524169922,-8.232318878173828,-10.492753028869629,-9.099151611328125 -4063,4063,E237V,0.016657895,0.016246553,-0.003499815,0.005257035,-0.232596251,0.150908039,0.023062700000000002,0.010253089,0.031151223999999998,0.01142821,0.021064895,-0.014502397,0.007502767,0.010829596,-0.000315526,-0.16783272300000002,-0.297359778,1.286751929,2.152541439,-6.363935059,-4.646724037,-8.195306038,-6.95441021,-5.924248207000001,-6.098986801000001,-3.4433719039999997,-0.23112915399999998,-7.761600494384766,-9.255759239196777,-6.206133842468262,-6.915491104125977,-6.400734901428223 -4064,4064,E237Y,0.03468529,0.03167615,-0.022749236000000003,-0.002681862,0.005440546,-0.018638248,0.027268042000000003,0.042102537,-0.033591441,0.039892097,0.023460202000000003,0.027770463,-0.073268935,-0.019408778,0.014045055,0.022172346000000002,-0.011291253999999999,1.269385316,2.7386993360000003,-7.294705696,-7.1429911420000005,-8.348777092,-7.013015952999999,-7.0739732360000005,-6.894771057000001,-4.59982177,-1.7497110930000002,-8.883076667785645,-10.339597702026367,-7.33065128326416,-8.860721588134766,-4.927180290222168 -4065,4065,R238A,0.013523674,-0.006739704,0.005233807,0.001631919,-0.19138277399999998,0.103106836,0.002081165,0.024966183,-0.044662852,-0.00037826,-0.013101148,0.019600328,-0.009132715,0.010257354,-0.006993516,-0.11972578800000001,-0.263039759,1.3547178530000001,2.295813115,,,,,,,,,-3.5011489391326904,-9.326050758361816,-8.321738243103027,-5.031181812286377,-6.734034538269043 -4066,4066,R238C,0.006360838000000001,-0.033718128,0.0067700519999999995,0.013370802,-0.055273876,0.107010355,-0.018394177,0.031115853,-0.023119319,-0.070497449,0.003061194,-0.004808982,0.018349086,0.000221862,0.026519741,-0.062240653,-0.048307099000000006,1.4413432019999999,2.542119829,,,,,,,,,-7.0816802978515625,-11.211359977722168,-10.090075492858887,-10.165521621704102,-11.585042953491211 -4067,4067,R238E,-0.022968665,0.029692102,-0.023085342999999998,-0.059469499,-0.540561517,0.045035146,-0.011106481000000001,-0.034830848,-0.060319005999999994,0.082152486,-0.022768282999999997,-0.05078478,0.004614095,0.00618871,-0.125127707,-0.311253214,-0.76986982,1.3633449880000001,1.921643466,,,,,,,,,-4.082751274108887,-10.65107250213623,-8.613326072692871,-5.110095500946045,-7.027387619018555 -4068,4068,R238D,0.044063275,-0.041944485,0.033812808,0.025038282000000002,-1.57260576,0.185830713,-0.0367761,0.12490265,-0.054581578,-0.098767298,0.014878328,0.013282005,0.05434361099999999,0.037357839,0.012718723999999999,-1.253680672,-1.8915308469999998,0.696717712,1.3362879429999999,,,,,,,,,-4.002119541168213,-10.658123970031738,-8.756505012512207,-5.668456554412842,-6.903151512145996 -4069,4069,R238G,0.061826717,-0.012828113,0.006560023000000001,-0.014056144,-0.10030088599999999,0.11551189099999999,0.039793422,0.083860012,-0.032907646,-0.030005061,0.004348835,-0.019326799,0.032446844,-0.030106625,0.001994337,-0.082427658,-0.11817411300000001,1.31083945,2.315669824,,,,,,,,,-4.222069263458252,-9.06065845489502,-8.0486478805542,-6.3145365715026855,-7.900356292724609 -4070,4070,R238F,0.029527999,-0.014591693000000001,0.059428278,0.020046416,-0.10410208900000001,-0.00254995,-0.024329616000000002,0.083385613,-0.11114960800000001,0.041871951,-0.071055336,0.085747004,0.033109551,0.023702958,0.016389874,0.070243931,-0.278448109,1.118628365,2.914811813,,,,,,,,,-2.016242027282715,-8.886823654174805,-7.316868305206299,-5.220441818237305,-5.983566761016846 -4071,4071,R238I,-0.009540119,0.079585897,-0.014749941,0.041987145,-0.6996986820000001,0.145213541,-0.089008089,0.069927852,-0.005096215,0.069858655,0.089313139,0.060677993,-0.090177874,0.089162945,-0.005188655,-0.503501711,-0.895895652,0.682807408,1.4356243819999999,,,,,,,,,-5.877477169036865,-11.194116592407227,-9.231245994567871,-7.710850715637207,-8.29259204864502 -4072,4072,R238H,0.055715427000000005,0.050251504,0.02029348,0.036135912,0.0399595,0.087740469,0.059939837999999995,0.051491015,-0.02407681,0.029860569,0.070642438,0.049718325,-0.009131366,0.046613046,0.025658777,0.062834074,0.017084925,1.137440462,2.850695777,,,,,,,,,-1.7846636772155762,-5.542411804199219,-4.826714038848877,-2.7175559997558594,-2.3326783180236816 -4073,4073,R238K,0.086896117,-0.114179264,-0.058299687,-0.024551467999999996,-0.166125883,-0.137545159,-0.016167021,0.189959254,0.038369479,-0.164810249,-0.063548279,-0.10772643800000001,-0.008872935,-0.16490485900000001,0.115801923,-0.144871436,-0.18738033,1.530227579,2.223333959,,,,,,,,,-4.352481842041016,-6.867650985717773,-5.949283599853516,-3.6169159412384033,-4.5567708015441895 -4074,4074,R238M,0.07450715200000001,-0.154587341,-0.077156442,-0.041714798,-0.112249205,0.011998868999999999,0.03281944,0.11619486400000001,-0.02737261,-0.231419722,-0.077754959,-0.145913983,-0.008398899999999999,-0.095294585,0.01186499,-0.14120205800000002,-0.083296352,1.433930912,2.17447863,,,,,,,,,-5.8711700439453125,-10.67890453338623,-9.045125961303711,-6.458796501159668,-8.469197273254395 -4075,4075,R238L,0.040988432000000005,0.014057097,0.035478592999999996,0.010212888,-0.16812058600000002,0.033932266,0.04165778,0.040319083,-0.008836126,0.018096191,0.010018002,0.042315937000000005,0.028641247999999998,0.023301656,-0.002875881,-0.090550853,-0.24569031800000002,1.383177731,2.37551118,,,,,,,,,-4.542302131652832,-8.33970832824707,-6.839991569519043,-5.730440139770508,-7.148567199707031 -4076,4076,R238N,-0.034636479,-0.095317611,-0.04953162,-0.095589699,0.034922647,-0.08682265,-0.063993816,-0.005279142,-0.285922825,-0.061269657000000005,-0.12936556400000002,0.026167142,-0.125230381,-0.04571845099999999,-0.145460946,0.053785651,0.016059642,1.192579612,2.685602053,,,,,,,,,-1.3398926258087158,-6.8782124519348145,-5.75993537902832,-3.1972475051879883,-3.274210214614868 -4077,4077,R238Q,0.10358189599999999,0.025034679,0.050150415999999996,-0.021896667,0.025892083,0.026169811,0.093168389,0.11399540300000001,-0.089917729,-0.010092898000000001,0.060162256,0.001743756,0.098557075,-0.039335155,-0.004458178,-0.021182192000000002,0.072966358,1.228637379,2.520725081,,,,,,,,,-3.7027275562286377,-6.942112922668457,-6.486562728881836,-2.4512381553649902,-5.080509185791016 -4078,4078,R238P,0.024899538,-0.007326929,0.00035961099999999997,-0.008658734,-0.41609155700000006,1.085101182,-0.0038290090000000004,0.053628085,-0.042972249000000004,-0.016926088,0.002272231,-0.020907237,0.021626457999999998,-0.030461752,0.013144285,-0.246293323,-0.585889791,1.376820247,2.0210286859999997,,,,,,,,,-5.300443172454834,-13.272256851196289,-11.341816902160645,-8.188782691955566,-8.790094375610352 -4079,4079,R238S,-0.0027567990000000003,-0.01001807,-0.009010505,-0.008344180999999999,-0.155113138,0.078984082,-0.030310273999999998,0.024796677000000003,-0.001410526,-0.0040145829999999995,-0.016021556,-0.009939947,-0.008081063000000001,-0.004823018,-0.011865343,-0.075726208,-0.23450006699999998,1.308196117,2.3759461859999997,,,,,,,,,-3.1240317821502686,-7.5410919189453125,-7.49560022354126,-5.277650833129883,-5.677939414978027 -4080,4080,R238T,0.007056598000000001,-0.045825303,-0.058790893,-0.0013215170000000001,-0.338669016,0.165629506,-0.019518857,0.033632052999999995,-0.012274799999999999,-0.053517922,-0.038132683,-0.07866858,-0.038913206,-0.010637843999999999,0.007994811,-0.205334419,-0.472003613,1.3936531330000002,2.178452388,,,,,,,,,-3.41460919380188,-8.457533836364746,-7.7882080078125,-5.499956130981445,-6.126697540283203 -4081,4081,R238W,0.007660385,-0.034941222,-0.037390028,-0.021497792999999998,-0.043960948,0.035100761,-0.016887244,0.032208014,0.043752352,-0.047431335,-0.022451109,-0.04863501,-0.026145045,-0.0053176840000000005,-0.037677902,-0.05022631,-0.037695585,1.283728439,2.377140616,,,,,,,,,-3.616245985031128,-10.926074981689453,-7.214155197143555,-8.530069351196289,-8.305724143981934 -4082,4082,R238V,-0.00942627,-0.021076475,-0.053167945,-0.049975949000000006,-0.238486991,0.14741346800000002,-0.016366651,-0.002485889,-0.0073464509999999995,0.000286821,-0.042439770999999994,-0.010937583999999998,-0.095398305,-0.034737604,-0.06521429299999999,-0.169314658,-0.307659324,1.231832495,2.019396992,,,,,,,,,-5.414272308349609,-11.800853729248047,-9.160630226135254,-7.155215263366699,-7.753234386444092 -4083,4083,R238Y,0.020920823999999998,-0.014267013,0.097452303,0.095098628,-0.015876186,-0.013467264,0.00688754,0.034954107000000005,0.044591569000000005,0.127642224,-0.15617624900000002,0.149450274,0.045454332,0.207093455,-0.0168962,0.060718242,-0.092470614,1.0580714359999999,2.8467654380000003,,,,,,,,,-1.185685396194458,-7.85561466217041,-5.417740345001221,-3.8840482234954834,-3.8148672580718994 -4084,4084,G239A,0.001909976,0.0046661229999999995,-0.007806648,-1.047147798,-1.979592571,0.023000187000000002,0.000558151,0.0032618,0.051486983,0.008320056999999999,0.001012189,-0.014491598999999999,-0.001121697,-0.5080322310000001,-1.586263365,-1.9300941930000002,-2.0290909480000003,1.7030476890000001,1.40304414,-6.350715509,-5.377266525,-11.35179063,-6.200394478,-4.76135936,-4.062766548,-4.913885982,-1.533644847,-7.6437602043151855,-7.398609638214111,-8.0078125,-7.819093704223633,-8.725675582885742 -4085,4085,G239C,-0.021357437000000003,-0.004849238,-0.056632231,-1.474953956,-2.4281445809999997,-0.071174405,-0.055634137,0.012919264,0.039722138,-0.018669349,0.008970874,-0.02462764,-0.08863682199999999,-1.197072243,-1.752835669,-2.303303751,-2.55298541,0.635493639,0.722194184,-11.58346454,-11.09735013,-15.85688959,-10.6822898,-10.99899721,-9.281795952000001,-8.897488482,-5.3558946380000005,-9.50273323059082,-12.68250560760498,-12.658981323242188,-11.973783493041992,-13.210355758666992 -4086,4086,G239E,-0.046728088,-0.183592544,-1.389513556,-1.875562709,-2.076001008,0.078745305,-0.01528748,-0.078168695,0.0018879839999999999,0.0016967929999999998,-0.36888188,-1.30268419,-1.476342922,-1.771611161,-1.9795142559999999,-2.2088358880000003,-1.943166128,3.627298362,2.176036025,-9.484589391,-8.966725922,-14.24223277,-8.394125602999999,-9.710336716,-6.10952594,-7.027869214,-3.7383546930000002,-10.318561553955078,-12.813346862792969,-9.03411865234375,-10.642544746398926,-10.799036026000977 -4087,4087,G239D,0.008714311,0.019566746,-1.106492416,-1.9893299819999999,-2.9632169489999995,0.00341126,-0.0026402609999999996,0.020068882,0.01605822,0.024738057,0.014395435,-0.897809746,-1.315175086,-1.733896391,-2.244763572,-2.8401278989999996,-3.0863059980000003,2.2441887730000003,1.03832865,-8.413449467000001,-8.218256493,-11.30835925,-8.265688042,-8.939020889,-5.335922668,-6.532757759,-2.7615929319999997,-9.706055641174316,-11.211447715759277,-8.505945205688477,-9.946091651916504,-8.98886489868164 -4088,4088,G239F,0.03096675,0.035093196,-1.186166216,-1.946611315,-2.2158135469999998,0.037685815,0.026160932,0.035772567000000005,-0.036707497,0.092619223,-0.022432831,-1.188040125,-1.184292307,-1.85533475,-2.03788788,-1.9615662580000002,-2.470060835,3.458641408,2.097905365,-11.25213823,-13.44058752,-15.04146086,-9.710364608999999,-11.55474697,-6.513531181,-7.41124219,-4.01969675,-11.15243148803711,-15.050342559814453,-13.148730278015137,-12.919971466064453,-13.831550598144531 -4089,4089,G239I,-0.015741086,-1.179491697,-2.043695784,-2.249033143,-2.367720376,-0.078508564,-0.051316416,0.019834245,-0.087311424,-0.852056512,-1.506926882,-2.0705679530000003,-2.016823614,-2.436832582,-2.061233703,-2.54306409,-2.192376662,1.302751413,-0.360332075,-11.00331891,-11.82043075,-14.49402286,-9.362343376,-10.31694462,-9.022852927999999,-7.269116039,-2.9294414410000003,-11.262102127075195,-14.977914810180664,-13.31898307800293,-12.487509727478027,-14.357278823852539 -4090,4090,G239H,0.016120136,0.059149050999999994,0.030095353,-1.4965751980000002,-2.5834250340000002,0.24699043399999998,0.004310963,0.027929309,0.00530115,0.073596622,0.04470148,0.069778487,-0.009587781,-1.223465204,-1.769685191,-2.350886011,-2.815964057,0.6075080389999999,0.717202443,-8.400404692,-9.615749603,-12.27359203,-6.284553505,-9.935687675,-3.8924406510000003,-5.828385311,-2.984032047,-9.911864280700684,-13.509017944335938,-11.069077491760254,-11.831878662109375,-10.957032203674316 -4091,4091,G239K,0.036394657000000004,-0.009619633,-1.058105408,-2.422242315,-2.8525541939999997,0.038310036,0.033558542999999996,0.039230771,0.006894531,-0.07334883099999999,0.054109565,-0.798726347,-1.317484469,-2.3954398969999997,-2.449044733,-2.501671405,-3.203436983,1.035420741,0.229645805,-10.18408251,-11.18211419,-12.71559509,-8.458586151,-10.91053208,-7.653585014,-8.190356716,-3.5246431210000004,-12.462604522705078,-12.14355754852295,-9.377202033996582,-11.25175952911377,-10.451705932617188 -4092,4092,G239M,0.036952763,0.031896943,-1.3120523590000002,-2.402990913,-2.8667761869999997,0.109325022,0.058943199,0.014962327,0.024374446,0.022849341000000002,0.040944544,-0.995190771,-1.6289139469999998,-2.551787098,-2.2541947280000003,-2.35698861,-3.376563763,0.545870292,0.102829382,-12.80048397,-13.15707536,-16.15085905,-11.957135300000001,-11.9995137,-10.73783642,-8.647575983,-5.235175498,-11.03586483001709,-14.41222858428955,-12.396345138549805,-12.280681610107422,-13.843085289001465 -4093,4093,G239L,-0.02939842,-0.602164272,-1.905582694,-2.1040501469999997,-2.898614068,-0.012302918000000001,-0.032824812,-0.025972027,0.017877257,-0.24944009,-0.9548884540000001,-1.779297795,-2.0318675930000003,-2.119233485,-2.088866809,-2.552823927,-3.244404208,1.063726662,-0.016636608,-12.2880638,-12.83794054,-14.78584284,-11.50994907,-12.47366219,-9.832924385,-8.058226907,-4.88891888,-10.23272705078125,-14.580080032348633,-10.759532928466797,-11.326617240905762,-13.275355339050293 -4094,4094,G239N,-0.046394232,-0.080821127,-0.062074112,-0.34396633200000004,-1.935226949,0.230407045,-0.023459942,-0.06932852099999999,-0.09949,-0.09832986099999999,-0.063312392,-0.027820214,-0.096328009,-0.095089017,-0.5928436460000001,-1.529700129,-2.340753768,0.8875397290000001,1.3348479640000002,-7.345668886,-7.8323325420000005,-10.0533922,-5.460829338,-7.662952934,-5.71883741,-5.782938698,-2.257144277,-6.468761444091797,-10.148307800292969,-8.197286605834961,-9.324797630310059,-6.873967170715332 -4095,4095,G239Q,-0.051212267,-0.004606337,-0.60027163,-1.855041404,-2.958203478,0.070802197,-0.051690608,-0.050733925,-0.032725726000000004,-0.020488416000000002,0.011275743000000001,-0.28164555199999997,-0.9188977070000001,-1.5918730509999999,-2.1182097559999997,-2.675828164,-3.2405787910000003,1.417485572,0.788285311,-9.250107822999999,-10.18820316,-13.6929044,-7.088618812999999,-9.699257843,-5.5815549010000005,-6.663909406,-3.6406527000000004,-10.1150541305542,-12.205734252929688,-10.18462085723877,-11.198691368103027,-10.825939178466797 -4096,4096,G239P,-0.030044671000000002,-0.788468433,-2.005819984,-2.3268610819999997,-3.013732415,-0.017026849,-0.035005921,-0.025083421,0.046021442999999995,-0.480416444,-1.096520422,-1.998481524,-2.013158443,-2.252772394,-2.40094977,-2.6222453359999998,-3.405219493,1.2970521990000001,-0.11011246400000001,-11.14717653,-10.63579541,-14.99861381,-11.46005156,-10.27268575,-8.36873613,-7.3783663,-3.7330633260000003,-11.980387687683105,-14.16680908203125,-14.220596313476562,-12.613226890563965,-15.342073440551758 -4097,4097,G239S,-0.036318762000000004,-0.0063973419999999994,-0.040629764,-0.888703372,-2.061764239,0.35870649299999996,-0.018824063000000002,-0.05381346,0.049168518,0.004046582,-0.016841266,-0.015057124,-0.066202404,-0.265788572,-1.511618172,-1.8260621769999998,-2.297466301,1.3084350009999999,1.352249773,-8.687387048,-8.043391243,-13.61787285,-7.759276695,-6.483983467000001,-7.532410988,-6.3779146870000005,-2.595907263,-5.862400054931641,-9.971363067626953,-8.335856437683105,-8.483545303344727,-8.74359130859375 -4098,4098,G239R,-0.022864891000000002,0.004651346,-1.069065344,-1.850444295,-2.175100285,0.025220657999999996,-0.0144523,-0.031277481,0.024959625,0.015781532,-0.00647884,-0.71787804,-1.4202526480000002,-1.779146486,-1.9217421030000001,-2.120590704,-2.229609866,3.322913849,2.0730124819999998,-8.846759003999999,-9.79658989,-12.24630949,-7.275723396,-9.936254005,-4.978918236,-6.390762218,-2.592075141,-11.345460891723633,-12.862117767333984,-9.90045166015625,-10.303973197937012,-10.86697769165039 -4099,4099,G239T,0.0006682610000000001,0.031157401,-0.95836082,-1.971784833,-2.909216932,0.206584023,0.0016414829999999998,-0.00030496099999999997,-0.00097512,0.012907822,0.04940698,-0.5350768379999999,-1.381644801,-1.7454376740000002,-2.198131992,-2.439940888,-3.378492975,1.77124818,0.854888028,-8.362096637999999,-7.507867202999999,-13.28994987,-7.436592484,-6.364152954,-7.211920677,-7.1165542870000005,-2.331966742,-6.847623348236084,-11.782634735107422,-10.920108795166016,-10.320432662963867,-11.311930656433105 -4100,4100,G239W,-0.049992484000000004,-0.516454345,-1.854888405,-2.104785648,-2.3449919059999997,0.051244985,-0.02385856,-0.07612640700000001,0.069411578,-0.159360076,-0.8735486140000001,-1.8524153490000002,-1.85736146,-2.253442085,-1.956129211,-2.359673592,-2.33031022,0.823901656,-0.052810498,-13.02576905,-13.61643104,-16.32357917,-12.4180429,-12.83293024,-9.937861908,-9.041201555,-5.938691254,-12.265743255615234,-14.660950660705566,-13.399106979370117,-14.035651206970215,-14.998571395874023 -4101,4101,G239V,-0.012061086,-0.801233897,-1.868598154,-2.138702757,-2.429759452,0.032445619,-0.00247561,-0.021646561,0.101497129,-0.522029896,-1.080437898,-1.958504547,-1.77869176,-2.098372799,-2.179032714,-2.563626249,-2.295892655,1.376463075,-0.08280204099999999,-9.77251927,-10.64894082,-13.79351885,-8.636477005,-9.257847115,-6.525812561,-6.724674695,-3.51152626,-10.256813049316406,-13.279664039611816,-11.944151878356934,-11.408844947814941,-13.62122631072998 -4102,4102,G239Y,0.054137135999999995,-0.009956839,-1.214222587,-2.2205899419999997,-2.951931816,0.058547232000000005,0.067656421,0.040617851,0.088485139,0.085813936,-0.10572761300000001,-1.193032071,-1.235413103,-1.9852654319999998,-2.455914451,-2.568618195,-3.3352454369999998,0.375886409,0.066190238,-10.54996781,-11.45608288,-14.96842617,-9.600451653,-10.84251923,-5.882359137999999,-7.2009264029999995,-3.664997576,-10.685522079467773,-14.004312515258789,-12.559966087341309,-13.067278861999512,-12.5139741897583 -4103,4103,S240A,0.014647166000000001,0.04287168,0.011648671000000001,-0.003480665,-0.022943869,-0.003432627,0.004032195,0.025262137,-0.04204393,0.027697431,0.058045929,-0.008074391,0.031371733,-0.038474292,0.031512962,-0.032764675,-0.013123063,1.263908535,2.456590378,-2.248778029,-1.708949036,-1.904252693,-1.935560425,-2.958933159,-2.736194832,-3.015460112,0.345458359,-5.84982967376709,-7.576202869415283,-4.424810409545898,-5.088863372802734,-4.838436126708984 -4104,4104,S240C,0.037620546,0.070984486,0.023259807,0.024609858,-0.932433747,0.17841447100000002,0.037692435,0.037548657,-0.043728504,0.072649436,0.069319536,0.026033663,0.020485951000000002,-0.016076214,0.06529593,-0.49142184899999997,-1.373445645,0.839613556,1.489518414,-9.056184189,-9.111981422000001,-8.763100463999999,-7.374000671,-11.14231943,-8.889518959,-7.31732263,-2.9090579069999998,-8.83344841003418,-12.267916679382324,-7.984016418457031,-9.19686222076416,-11.036642074584961 -4105,4105,S240E,-0.076451975,0.059229322,0.023507772000000003,0.054374492,-0.725830676,0.054118165999999995,-0.13249650699999999,-0.020407441999999998,0.054115446,0.08768633699999999,0.030772307000000002,0.004387366,0.042628177999999996,0.017873368,0.090875615,-0.48484489,-0.966816461,0.8357402970000001,1.4909331730000002,-8.748148415,-8.666740509,-7.5302069320000005,-8.652781731000001,-10.45845785,-8.432555054,-6.027861883,-2.132577997,-5.661244869232178,-13.666376113891602,-8.768861770629883,-10.648634910583496,-9.6011323928833 -4106,4106,S240D,-0.053387797,0.026452073,-0.027099816000000002,-0.124852755,-1.862349445,0.264060923,-0.09368,-0.013095593999999999,0.071766978,-0.007555681,0.060459827,-0.071224761,0.017025129,-0.030568436,-0.21913707300000002,-2.00480407,-1.719894819,0.8557448590000001,1.3028902820000001,-10.43915103,-10.61284664,-10.40271841,-9.27614447,-12.30038206,-9.603663574,-7.692835923,-3.852939978,-5.801515579223633,-12.665124893188477,-9.35406494140625,-10.002751350402832,-9.751842498779297 -4107,4107,S240G,0.022606177,0.023675744,-0.006154675,0.003864387,-0.030204569,0.41831645700000003,-0.023578521,0.068790874,-0.022554106,0.023016395,0.024335093,-0.045312057999999995,0.033002708,-0.012523933000000001,0.020252706000000002,-0.061926687,0.00151755,1.388676475,2.495855297,-5.092763226000001,-4.24506588,-3.365251045,-4.1400077589999995,-6.671947417999999,-7.041544029,-5.765593895,-0.8976415640000001,-6.175414562225342,-8.083840370178223,-7.196704864501953,-8.04632568359375,-7.8387675285339355 -4108,4108,S240F,-0.029228062000000003,0.005170654,-0.212806845,-1.82511757,-2.1783692080000003,-0.07344552900000001,-0.033065847,-0.025390276,-0.030720493999999997,-0.009267375999999999,0.019608683000000002,-0.11597108800000001,-0.309642602,-1.728527277,-1.9217078630000002,-2.2256416569999997,-2.131096759,1.0048078040000001,0.705535844,-11.51816847,-12.23535089,-11.00720971,-9.617896446,-15.73242104,-8.997964248999999,-6.793336011,-2.558892643,-9.419634819030762,-11.872369766235352,-9.255987167358398,-10.460772514343262,-12.523698806762695 -4109,4109,S240I,0.041438765,-0.476190251,-1.96507792,-2.212159014,-2.406031271,0.052659733,0.038363577999999995,0.044513950999999996,-0.116881094,-0.171834032,-0.780546469,-1.592484513,-2.337671326,-1.97973142,-2.4445866080000003,-2.078905791,-2.73315675,4.058217474,2.391368569,-9.741262784,-11.00340344,-10.71112164,-8.368944115,-12.24118104,-6.381663689,-5.062078138,-0.360292059,-8.67974853515625,-11.73460578918457,-6.30035924911499,-8.222740173339844,-10.077072143554688 -4110,4110,S240H,-0.014579481000000002,0.009177225,-0.041348351,-0.005660976,-1.7967942819999998,0.005638745,-0.029473552000000004,0.00031459,-0.0465464,-0.048846336,0.067200785,-0.10432093699999999,0.021624236,-0.075866599,0.064544648,-1.620125992,-1.973462571,0.968150187,1.3345539659999999,-11.66624361,-12.01230915,-10.89983774,-8.19810537,-15.58468805,-11.63627774,-7.058853111,-3.3276634080000003,-8.356989860534668,-13.593748092651367,-9.497713088989258,-11.459846496582031,-11.978271484375 -4111,4111,S240K,-0.006614773000000001,-0.147587833,-1.638797955,-1.735364052,-2.27872131,-0.18490237899999998,-0.022698785,0.00946924,-0.006074148000000001,0.085290478,-0.380466144,-1.71742325,-1.560172659,-1.803640161,-1.667087942,-1.9028145319999998,-2.654628088,4.274744622,2.6929237489999998,-11.83511694,-10.10433186,-9.525652115,-10.22950117,-15.12778197,-14.18831757,-7.046758199999999,-2.611570104,-8.130306243896484,-11.321429252624512,-9.041836738586426,-11.599746704101562,-9.805767059326172 -4112,4112,S240M,-0.053300474,-0.02908226,-0.03242939,-1.9553361790000001,-2.600753429,0.013747405,-0.064077336,-0.042523610999999996,-0.124017645,0.050305117999999996,-0.10846963800000001,-0.02047205,-0.04438673,-1.207920348,-2.70275201,-2.210184705,-2.991322152,2.226515296,1.43697974,-10.78746736,-10.63642024,-9.239874648999999,-10.01712814,-14.80271816,-9.241195587,-6.232574323,-1.7052540530000002,-8.972370147705078,-11.382543563842773,-7.548544406890869,-8.94314193725586,-9.992755889892578 -4113,4113,S240L,-0.006525895,0.012265038999999998,-1.211545501,-1.9746876,-2.888226204,-0.013294256,-0.003489258,-0.009562530999999999,-0.022362985,0.049355947000000004,-0.02482587,-1.056747773,-1.366343228,-2.015385851,-1.933989349,-2.678831653,-3.097620754,2.258446528,0.920188867,-12.04377773,-12.65058064,-11.58836924,-10.49254511,-16.40961912,-9.077774536,-7.056188848,-0.31470181399999997,-7.530219554901123,-11.799469947814941,-7.748920440673828,-8.876556396484375,-10.564882278442383 -4114,4114,S240N,-0.106726605,-0.018215751000000002,0.031108011,-0.097609826,-0.913859267,0.055278325,-0.16656773800000002,-0.046885471,-0.017490732,-0.139649349,0.10321784699999999,-0.02722717,0.08944319199999999,-0.20158017,0.006360519,-1.057716492,-0.7700020409999999,1.5116560890000001,1.566086053,-7.758796128999999,-7.930515465,-6.3279529420000005,-5.364080521,-12.32642848,-6.845003235,-5.118234987,-2.61397371,-6.183409690856934,-9.267578125,-6.384548664093018,-8.559276580810547,-8.315300941467285 -4115,4115,S240Q,-0.0092215,0.051296904000000004,0.033281614,-0.0032205479999999997,-1.606006606,0.156544485,-0.008838861,-0.009604138,-0.082614422,0.04626943099999999,0.056324375999999995,0.021529292000000002,0.045033936,0.011700727,-0.018141822,-1.527682816,-1.684330395,0.485066141,1.309037037,-11.71454063,-10.59190579,-10.631098099999999,-10.55950613,-15.18730841,-11.60288471,-6.758813166,-3.2960634719999997,-7.055031776428223,-12.55078411102295,-8.937234878540039,-10.818467140197754,-10.231558799743652 -4116,4116,S240P,-0.012011325,-0.136174601,-1.40660669,-2.118872495,-2.7548283689999997,-0.0084976,-0.041459759,0.017437109,-0.035910033,0.012437905,-0.284787106,-1.282362413,-1.530850966,-2.115131588,-2.122613402,-2.6179982969999998,-2.891658441,0.94060404,0.096316325,-10.80836781,-10.11033876,-12.0477924,-9.181198708,-12.45706288,-10.24544629,-7.456460937999999,-3.316222515,-8.800960540771484,-13.743999481201172,-9.358909606933594,-9.088367462158203,-10.688950538635254 -4117,4117,S240R,0.004842682,-0.00639161,-1.198689776,-2.192751031,-2.648062661,-0.066925953,-0.021888533999999998,0.031573897999999996,-0.061003789,0.004082284,-0.016865504,-0.910675199,-1.4867043519999998,-2.252164615,-2.1333374469999997,-2.874217732,-2.421907589,1.8179582069999998,0.633341086,-13.88855818,-13.01731786,-14.78807972,-11.08666785,-15.87378561,-14.67693988,-6.608010375,-1.206850116,-7.966779708862305,-11.636197090148926,-9.024892807006836,-11.293286323547363,-10.478724479675293 -4118,4118,S240T,-0.017192358999999997,0.027964719,0.002360835,-0.039387726,-1.164781075,0.016033072,-0.029957951,-0.0044267659999999995,0.007286991,0.037142385,0.018787052,-0.005458825,0.010180494,-0.025979916000000002,-0.052795536,-0.896674959,-1.43288719,0.775985507,1.379658729,-2.821457811,-2.539737953,-3.4088088460000003,-2.0148983080000002,-2.857323547,-3.286520401,-3.0597334,0.6761057,-5.225547790527344,-6.784786701202393,-1.915258765220642,-3.6067404747009277,-4.395648002624512 -4119,4119,S240W,-0.019713187,-0.758188772,-2.171904949,-1.971657634,-2.353095749,-0.029746582999999997,-0.02961271,-0.009813663,-0.052197756,-0.501573151,-1.014804393,-2.6407891930000003,-1.703020705,-1.948854853,-1.994460414,-2.826180475,-1.880011022,0.258771612,-0.51517389,-14.25278716,-14.24157705,-13.91144769,-12.12958925,-17.0298372,-13.951484599999999,-8.28740065,-4.297872638,-10.860555648803711,-14.288592338562012,-11.523921966552734,-12.25119400024414,-14.110471725463867 -4120,4120,S240V,0.032684209,0.007553882,-1.030665821,-1.7641267330000001,-2.206336385,-0.032732374,0.019903791,0.045464625999999994,-0.014043077,-0.024607969,0.039715732999999996,-0.62187966,-1.4394519819999998,-1.8999820969999999,-1.6282713690000001,-2.351338986,-2.061333784,1.865558038,0.83584986,-8.76306546,-9.826564095,-10.60326877,-7.805614471,-9.950149193,-5.6297307739999995,-4.833311757,0.496939597,-8.013701438903809,-10.835807800292969,-5.862125396728516,-6.681986331939697,-8.70924186706543 -4121,4121,S240Y,0.075639975,0.064536737,-0.46994701,-1.4975787969999999,-2.128981685,-0.10407870699999999,0.069139836,0.082140114,-0.062555504,0.01900028,0.110073194,-0.168910993,-0.770983027,-1.4482525030000002,-1.54690509,-2.246396878,-2.011566491,1.107778403,0.7523349559999999,-11.75838981,-12.28574372,-10.59578602,-8.527073067,-15.88397907,-11.49936717,-6.59638858,-2.959096153,-9.276789665222168,-12.149861335754395,-9.445216178894043,-10.634193420410156,-11.719793319702148 -4122,4122,R241A,0.034593009,0.033313734,0.040180392,-1.3204279490000002,-2.0916275509999998,-0.11969009300000001,0.043031812,0.026154205,-0.022570501,0.061585445,0.005042023,0.057419459000000006,0.022941324,-1.017667081,-1.6231888159999999,-1.9701186819999998,-2.21313642,3.21787308,2.42544262,-11.30024273,-13.03533869,-10.54232766,-8.91739196,-11.60693608,-12.39921925,-5.44537278,-0.956594715,-10.123079299926758,-9.881125450134277,-9.740842819213867,-13.189695358276367,-12.857626914978027 -4123,4123,R241C,-0.031404205,0.051584705999999994,0.029209912,-1.173632658,-1.452284211,-0.07890087400000001,-0.036839687,-0.025968723,-0.038881485,0.103441079,-0.000271667,0.140636075,-0.08221625099999999,-0.8733418070000001,-1.4739235080000002,-1.465641961,-1.4389264609999999,3.259127358,2.684509563,-12.85110836,-11.94312028,-11.47337929,-12.55052983,-13.47295764,-14.81555478,-7.517223018999999,-3.01295916,-9.90530776977539,-10.04839038848877,-9.473678588867188,-13.606510162353516,-11.391992568969727 -4124,4124,R241E,0.014826033,-0.015203806,-0.42754917200000003,-1.5586590319999998,-2.959300658,-0.07513953,0.021140309,0.008511757,-0.008482633,-0.004016025,-0.026391587,-0.084706633,-0.77039171,-1.522127223,-1.59519084,-2.237666329,-3.680934986,0.919229884,0.716212843,-13.73643701,-17.51842941,-11.94104588,-11.82236833,-14.76764871,-12.63269271,-7.500102303999999,-1.6435470269999999,-11.924304008483887,-12.509794235229492,-12.00718879699707,-15.799809455871582,-14.225728988647461 -4125,4125,R241D,0.01745611,-0.076117713,-1.165886901,-2.563756685,-2.651565275,-0.07178810099999999,0.028574369,0.00633785,-0.004502949,0.070411775,-0.22264720100000002,-1.016391305,-1.315382496,-2.424623506,-2.702889864,-2.335682423,-2.967448127,0.54153325,0.097891039,-13.64692426,-17.0015833,-14.03822873,-12.0828095,-13.38019002,-11.73180975,-7.62633047,-2.725776423,-13.155618667602539,-13.937263488769531,-12.6657075881958,-16.873266220092773,-14.815146446228027 -4126,4126,R241G,0.011906495,0.0028577840000000004,-0.011041947,-0.380109442,-1.734141371,-0.07669516700000001,0.001028804,0.022784186,0.00800015,0.010427931,-0.004712364,-0.020604779,-0.001479114,-0.13735966900000002,-0.622859215,-1.584687182,-1.883595559,1.019141708,1.341715451,-14.65443616,-17.37099989,-13.70855297,-12.60731023,-15.52452294,-14.06079476,-7.373169421,-3.7569556019999997,-10.889627456665039,-10.21881103515625,-10.210586547851562,-14.080924987792969,-12.131332397460938 -4127,4127,R241F,-0.024787012,0.00875149,-0.64979902,-1.764842636,-3.1106708860000003,-0.095421585,-0.010697934,-0.03887609,0.005338975,0.094621499,-0.07711852,-0.279568405,-1.0200296340000001,-1.696179537,-1.833505734,-2.628427753,-3.592914018,1.1538986629999999,0.725994933,-12.43081222,-13.03544014,-10.89002439,-11.31325642,-12.6608269,-14.25451323,-6.577830232999999,-2.902312775,-12.047602653503418,-11.953593254089355,-9.07484245300293,-14.625268936157227,-13.616528511047363 -4128,4128,R241I,-0.013066701000000002,0.015932973,-0.054218598,-1.6680823530000002,-2.126474784,-0.026963214,-0.0007030439999999999,-0.025430357,-0.011482931000000002,0.021298842000000002,0.010567103000000001,0.022650372999999998,-0.13108756900000001,-1.443025077,-1.8931396280000001,-2.308326503,-1.944623065,0.817757974,0.7182361620000001,-11.77907322,-14.17737931,-12.16146342,-10.18150935,-11.49224924,-10.88276477,-7.330785375,-2.235129835,-11.460329055786133,-10.234046936035156,-9.278356552124023,-12.824496269226074,-12.455292701721191 -4129,4129,R241H,0.019062724,0.0014060070000000001,-0.005179293,-1.064610456,-1.777018224,-0.112682724,0.04024897,-0.002123523,-0.014153836999999999,-0.005228707,0.008040720999999999,0.005682952,-0.016041536999999998,-0.8076587270000001,-1.321562184,-1.5699759919999998,-1.984060455,2.893909877,2.295703138,-8.240152638,-10.43017805,-7.779297577,-7.42847184,-7.549151527,-8.013664200000001,-7.632182704,-2.620532368,-9.783486366271973,-9.95386028289795,-6.838798999786377,-10.874444007873535,-9.482596397399902 -4130,4130,R241K,0.046051838,0.047101974000000005,-0.038313137000000004,0.023925123,-1.5078172159999998,-0.070776851,0.066664471,0.025439204,-0.0057696019999999995,0.099025827,-0.004821879,0.0016531979999999998,-0.07827947099999999,0.111394433,-0.063544188,-1.300687691,-1.7149467409999999,0.55664262,1.321871757,-8.889882747,-10.7338609,-8.043897263,-8.105034103,-9.154072029,-8.412549438,-7.757908788,-3.8462028669999997,-9.502237319946289,-8.655694007873535,-8.977267265319824,-9.157075881958008,-9.580121040344238 -4131,4131,R241M,0.042108411,0.018826722,0.019520253,-1.6121712430000001,-1.990657395,-0.101458809,0.043545872,0.04067095,-0.01877311,0.003521629,0.034131813999999996,-0.015380142,0.054420647,-1.071644344,-2.152698141,-2.0434011009999997,-1.937913688,2.277414835,1.555363719,-10.19033618,-11.66319719,-9.187466331,-9.575750481,-9.314722145,-11.21054475,-7.056193131000001,-3.401153036,-12.200523376464844,-11.60734748840332,-9.41805362701416,-12.876270294189453,-12.539092063903809 -4132,4132,R241L,-0.026596828,-0.018877137,-0.041630805,-1.436486669,-2.0114707480000003,-0.103056131,-0.009695376,-0.043498279,-0.024099122999999997,0.035405856,-0.07316013,0.058621803,-0.141883413,-1.25928438,-1.6136889580000002,-2.017821038,-2.005120457,2.388186356,1.595702133,-9.362577834,-10.8133187,-8.140190521000001,-7.71786599,-9.81294828,-10.32856567,-6.957559774,-2.0464285490000003,-10.34334659576416,-11.152527809143066,-8.085882186889648,-12.76098346710205,-10.920385360717773 -4133,4133,R241N,-0.021572766,-0.013714809,-0.026788792999999998,-1.112261388,-1.992377845,-0.023699373,-0.00775863,-0.035386902000000005,-0.073720588,0.040599977999999995,-0.068029595,0.003070147,-0.056647733,-0.7047797090000001,-1.519743066,-1.7339379380000002,-2.2508177519999997,2.163906295,1.659054508,-11.32775862,-11.98449304,-11.42015608,-10.14130768,-11.41435835,-11.67847797,-5.491333458,-2.481570683,-7.319989204406738,-9.407219886779785,-9.16593074798584,-12.160698890686035,-11.365852355957031 -4134,4134,R241Q,0.054715823,0.023750611,0.035754436,-0.8995478290000001,-1.993369224,-0.079126788,0.06004499,0.049386655,-0.013291194,0.018679955,0.028821267,0.021961573999999998,0.049547297000000004,-0.518770236,-1.280325421,-1.612550991,-2.3741874569999997,1.874814006,1.556200955,-10.02741834,-10.91675191,-9.497010468,-8.860969543,-11.27398707,-9.588372688,-7.688362044,-2.649398676,-9.419075965881348,-10.383101463317871,-8.1902494430542,-11.158699035644531,-10.190048217773438 -4135,4135,R241P,0.009473081,-1.4697481140000002,-1.673374965,-1.788275454,-2.096688393,-0.021387608,0.027353097000000003,-0.008406935,-0.046283871,-1.4062294709999998,-1.5332667569999998,-1.8024337869999998,-1.5443161419999998,-1.778066677,-1.798484231,-1.893245576,-2.30013121,0.130367061,-0.8502122440000001,-15.55998061,-16.71843114,-14.86606956,-14.96729513,-16.06903962,-15.179067600000002,-9.755191922,-6.295671412000001,-13.875866889953613,-13.154579162597656,-12.996883392333984,-16.168766021728516,-14.72883415222168 -4136,4136,R241S,-0.013676263999999999,0.008694949,-0.014958192,-0.016257056000000002,-1.359872404,-0.078648736,-0.013136135,-0.014216393,-0.005868274000000001,0.044816022999999997,-0.027426125,0.003350428,-0.033266811,0.068785829,-0.10129994,-1.3502252869999998,-1.369519521,2.5007450980000003,2.2322910730000003,-11.78566299,-12.28126911,-9.900953857000001,-11.69757943,-11.68142487,-13.367087699999997,-5.995591737000001,-1.7728034819999998,-9.53114128112793,-9.765850067138672,-9.194720268249512,-12.180317878723145,-11.399757385253906 -4137,4137,R241T,0.030332524,0.013484788999999999,0.015553299,-0.19138275899999999,-1.666129269,-0.087208325,0.025909782000000003,0.034755266,-0.015726962,0.034435557,-0.00746598,-0.00018056099999999998,0.031287157999999995,-0.032974881,-0.349790636,-1.5266652369999998,-1.8055933000000002,0.830430723,1.328026579,-12.09644727,-11.97427353,-11.61953421,-12.25118679,-11.65919806,-12.97804374,-5.409067245,-0.775256693,-9.783428192138672,-10.296210289001465,-9.964969635009766,-12.288257598876953,-11.764378547668457 -4138,4138,R241W,0.04206307,-0.037484847,-1.1678993340000001,-1.967444461,-2.702348336,-0.097878609,0.07026458599999999,0.013861554,-0.030770887,-0.008355020999999999,-0.066614673,-0.918142483,-1.417656185,-1.846424139,-2.088464782,-2.477642359,-2.927054312,2.348879139,1.093491084,-12.19103323,-12.44103796,-11.70186058,-10.69430461,-13.86588339,-12.25207961,-8.195255951,-4.718085304,-12.56515121459961,-14.516674995422363,-9.888239860534668,-14.483054161071777,-12.532143592834473 -4139,4139,R241V,0.014721255,0.013310777,0.00988001,-1.4085874669999998,-2.026693096,-0.052529565,0.025116572,0.004325938,-0.033002275,0.026312062999999997,0.00030949,0.06717466799999999,-0.047414649,-1.244250324,-1.57292461,-2.10955175,-1.9438344419999998,2.320028209,1.5172927319999998,-11.73726063,-12.99162476,-11.53285156,-10.56671231,-12.88388171,-10.71123279,-6.440676297,-1.4971511530000001,-10.755430221557617,-11.39163875579834,-9.859630584716797,-13.355585098266602,-12.965593338012695 -4140,4140,R241Y,-0.0069655509999999995,0.012177525,-0.962852965,-2.0099403319999998,-3.1178274910000003,-0.079916174,0.024028992000000002,-0.037960094,0.006576927,0.053163017,-0.028807968,-0.6833810290000001,-1.242324901,-1.772671645,-2.247209019,-2.81406433,-3.4215906510000003,1.894122131,0.8732641790000001,-12.27465176,-15.67427855,-12.71191299,-11.50034962,-11.00994752,-10.47677013,-7.183835805,-1.982449093,-11.47054672241211,-8.565977096557617,-6.500920295715332,-13.473292350769043,-11.817365646362305 -4141,4141,G242A,0.019968479,-0.019883981999999998,0.0034657570000000003,-0.012514385,-0.296453177,0.034622018,0.008288929,0.031648027999999995,-0.017195342,-0.041342647999999996,0.001574684,-0.006063122,0.012994635,-0.044027422000000004,0.018998653,-0.161698342,-0.431208011,1.5339614240000001,2.270422064,-2.9231305539999997,-3.6990882419999997,-2.718300697,-3.153576599,-1.6307879330000001,-3.4138992999999993,-3.486783934,-0.8348919509999999,-4.807342529296875,-4.740873336791992,-5.484825611114502,-6.665693759918213,-8.31074047088623 -4142,4142,G242C,-0.02794067,0.08428548599999999,-0.071635801,0.035396777000000004,-2.027301849,0.022479061,-0.083980921,0.028099581000000002,0.032736981,0.030142687999999997,0.138428283,-0.11810937,-0.025162232000000003,0.041935738,0.028857816,-1.577884443,-2.4767192540000003,0.58790787,1.311444705,-9.484352937,-9.436618805,-10.033762699999999,-10.03131647,-7.9762073970000005,-9.943859314,-6.216412279,-1.000176927,-9.809691429138184,-9.517810821533203,-9.628044128417969,-9.79097843170166,-11.807185173034668 -4143,4143,G242E,0.047079483,-0.7091781909999999,-1.947909869,-2.019097557,-3.223613025,-0.044543503,0.033582851000000004,0.060576115,-0.038405924,-0.319931994,-1.098424388,-2.1888682619999997,-1.706951475,-2.135023243,-1.9031718709999998,-2.8585928610000004,-3.588633189,0.593214537,-0.35953710899999997,-11.97965085,-12.08102246,-10.13479467,-12.97929693,-10.68766671,-14.01547349,-9.36387064,-7.989895928999999,-11.6136474609375,-13.8425931930542,-11.604331016540527,-13.184619903564453,-14.189665794372559 -4144,4144,G242D,0.059654078,-0.927510732,-2.293886831,-2.263309766,-2.669919713,-0.01547825,0.069329991,0.049978165,0.037529243999999996,-0.5763264220000001,-1.278695042,-2.359726994,-2.228046668,-2.430820712,-2.095798819,-2.552330339,-2.7875090869999997,0.331494165,-0.517508637,-10.07526339,-10.37248876,-9.819390106,-10.5269671,-8.807720558,-10.84975043,-5.765351645,-2.240308421,-10.563610076904297,-11.098642349243164,-11.167391777038574,-12.262313842773438,-12.762571334838867 -4145,4145,G242F,0.012458878999999999,-1.6620958259999998,-2.077613387,-2.256600975,-3.052286547,-0.057445046,0.027524911000000003,-0.002607153,-0.06819708099999999,-1.7650419019999999,-1.55914975,-1.98318513,-2.172041643,-2.531400102,-1.9818018469999998,-2.652909729,-3.451663365,-0.17197271,-1.082036255,-17.54349386,-15.40505966,-19.95554143,-18.272968600000002,-16.59588768,-17.48801191,-9.36387064,-7.989895928999999,-13.950276374816895,-12.02009391784668,-14.427106857299805,-13.89130973815918,-17.24374008178711 -4146,4146,G242I,0.039835043,-1.480163282,-2.669445131,-2.459357094,-2.8324936469999997,0.027044502,0.033520744,0.046149342,-0.041395976,-1.2440151609999999,-1.7163114030000002,-2.416400899,-2.922489362,-2.487494617,-2.4312195709999997,-2.3079742480000003,-3.357013045,0.44679917799999996,-0.749588788,-13.79686815,-12.73304449,-16.51981239,-14.14848635,-11.27984464,-14.30315286,-6.692846389,-2.969460901,-12.622871398925781,-8.753702163696289,-13.497451782226562,-10.219883918762207,-15.526347160339355 -4147,4147,G242H,-0.017238353,-0.022541111000000003,-1.209522301,-2.04438682,-3.045159625,0.071388884,-0.036087599,0.001610893,0.038690591,0.044383127,-0.08946534800000001,-1.0119092809999999,-1.40713532,-1.912306772,-2.1764668680000003,-2.63587639,-3.45444286,2.268281116,0.9791622190000001,-11.34400576,-7.7227354429999995,-11.96367124,-11.89716888,-9.193399857000001,-15.94305336,-5.206718582,1.0358307070000001,-13.141048431396484,-14.704200744628906,-13.606199264526367,-13.240606307983398,-15.06259536743164 -4148,4148,G242K,-7.269999999999999e-05,-1.9372397419999998,-2.355990324,-2.534977912,-2.908114465,-0.018763095,-0.00621108,0.006065645,-0.043322491,-2.401221076,-1.4732584080000002,-2.193395572,-2.518585075,-1.963459294,-3.10649653,-2.3859989169999998,-3.430230012,-0.589308439,-1.164380424,-13.38763742,-12.3456992,-12.36858765,-13.93809781,-11.90908575,-16.3767167,-9.36387064,-7.989895928999999,-13.49332046508789,-16.525772094726562,-15.278301239013672,-13.339921951293945,-16.323383331298828 -4149,4149,G242M,-0.030341482000000003,0.021814165,-1.240125203,-2.645899357,-3.01903591,0.006358096999999999,-0.027297542999999997,-0.033385421,-0.037822109,0.056765168,-0.013136838999999999,-0.818520868,-1.6617295369999998,-2.328947279,-2.962851435,-2.450456906,-3.587614913,0.7695754690000001,0.16286388400000001,-13.66170345,-13.12341527,-14.96220249,-14.58538364,-11.81028213,-13.82723373,-6.794746247000001,-2.6263973309999997,-12.490310668945312,-11.012720108032227,-13.553182601928711,-10.013402938842773,-16.016132354736328 -4150,4150,G242L,0.004138069,-1.8057455880000002,-2.258671369,-1.9605377019999999,-3.304678282,0.031867696,-0.01505875,0.023334887999999998,-0.047946347,-2.027219075,-1.584272101,-2.421453562,-2.095889175,-2.015426025,-1.905649379,-3.011996916,-3.5973596469999998,-0.530072135,-1.145908084,-13.42630293,-11.171926800000001,-14.45627978,-15.15536514,-12.61768926,-13.73025369,-5.95038209,-2.416103581,-11.947429656982422,-10.251053810119629,-12.620153427124023,-11.160921096801758,-15.915325164794922 -4151,4151,G242N,0.050680058,0.05806449599999999,0.023493532,-1.443334135,-2.883240142,-0.006618384000000001,0.044711376,0.056648739000000004,-0.105273165,0.063219147,0.052909844000000004,0.171108183,-0.124121119,-1.152231585,-1.734436684,-2.477861195,-3.288619088,0.43506133,0.711720285,-5.4519826810000005,-3.8917257610000004,-5.487293739,-5.437034232999999,-3.4830976560000004,-8.960762016,-3.147978094,2.092658447,-7.874476432800293,-11.677820205688477,-10.49894905090332,-8.565053939819336,-8.936893463134766 -4152,4152,G242Q,-0.038406096,-0.065172092,-1.555720351,-2.43797803,-2.811114583,0.049681324000000006,-0.02452216,-0.052290032,0.026989932,0.014902721,-0.145246905,-1.3741921259999998,-1.737248575,-2.37470477,-2.5012512890000003,-2.4962143969999997,-3.126014768,0.49666654200000004,0.048585479,-12.96810395,-11.38536564,-11.69882542,-14.47567482,-10.96360384,-16.31705,-8.042506457,-4.853139761,-12.368990898132324,-13.781072616577148,-13.36927604675293,-12.278247833251953,-15.336149215698242 -4153,4153,G242P,0.019894371,-1.6267619530000001,-2.2777156659999998,-2.3339217430000003,-2.566195875,0.012166202,-0.012963742,0.052752484,-0.03788816,-1.629393219,-1.624130686,-2.1785296659999998,-2.376901665,-2.39575142,-2.272092065,-2.517261047,-2.615130703,-0.30166681100000003,-1.048345528,-12.46006301,-12.32502893,-12.48947481,-13.10456232,-11.23329959,-13.14794939,-9.36387064,-7.989895928999999,-11.311264991760254,-11.769084930419922,-13.971939086914062,-16.00516128540039,-16.28435707092285 -4154,4154,G242S,-0.0021627179999999997,0.007008101,0.019852939,0.032287125,-1.0115331779999999,-0.046007477000000005,-0.013968507,0.009643071999999999,0.007749151,0.038450381,-0.024434179,0.041444194,-0.0017383160000000002,0.040137128,0.024437121000000003,-0.590491845,-1.4325745109999999,0.7217375690000001,1.418405045,-3.046935623,-3.8234070210000004,-2.267185654,-3.589347816,-2.286620132,-3.268117493,-2.974873642,-0.12341295099999999,-6.025897026062012,-7.708653926849365,-6.132473468780518,-7.541114330291748,-8.006973266601562 -4155,4155,G242R,-0.0036276040000000004,-1.7439139769999998,-2.060574002,-2.233552101,-2.6985392139999997,-0.022736546,-0.027984123,0.020728915,-0.089629304,-1.873896281,-1.6139316730000002,-2.025092719,-2.096055285,-2.12837112,-2.338733082,-2.322431415,-3.074647012,-0.46698059399999997,-1.1258706859999998,-15.96982515,-12.3164422,-15.973057500000001,-17.72762822,-13.79948146,-20.03251639,-9.356225304,-7.961305169,-12.309633255004883,-15.146491050720215,-12.975866317749023,-12.717405319213867,-15.464576721191406 -4156,4156,G242T,-0.006713652,0.0030825709999999997,-1.225077446,-2.064022705,-2.8794625480000002,0.072060647,-0.028665889,0.015238585,-0.058683578,0.040678883,-0.034513742,-0.795455563,-1.654699329,-2.052185858,-2.0758595509999997,-2.474725481,-3.284199615,1.9198680419999998,0.7806599479999999,-7.478744797,-8.172118492000001,-6.9020060270000005,-8.721787788,-5.0872030939999995,-8.510608582,-5.710115312999999,-1.7639181780000002,-9.369925498962402,-10.253985404968262,-10.552132606506348,-9.949831008911133,-12.420979499816895 -4157,4157,G242W,-0.011548181999999999,-1.703825526,-2.127367915,-2.745488706,-2.9346368660000004,0.058779047,-0.00737699,-0.015719373999999998,-0.087303071,-1.7844378280000002,-1.623213223,-2.178672315,-2.076063515,-2.5507960290000002,-2.940181382,-2.973335651,-2.89593808,-0.326238774,-1.113085917,-16.00344075,-13.87773368,-16.07976348,-17.68528578,-14.60468019,-17.76974064,-9.36387064,-7.989895928999999,-14.89234447479248,-14.499786376953125,-14.76751708984375,-15.107650756835938,-18.091922760009766 -4158,4158,G242V,-0.033050471,-0.531326134,-1.790027489,-2.381803028,-2.889362236,0.028155857000000003,-0.034184946,-0.031915996,0.028551122999999998,-0.238196562,-0.824455705,-1.776832266,-1.8032227109999999,-2.200108502,-2.563497553,-2.92367812,-2.855046352,1.134900611,0.004831487,-10.58243262,-10.00744237,-13.78068269,-10.74166592,-7.499488815,-10.88288329,-6.090385576,-2.019193853,-10.574698448181152,-7.649852275848389,-11.194965362548828,-10.592574119567871,-14.443023681640625 -4159,4159,G242Y,0.09374505400000001,-1.6742493219999999,-1.911044105,-2.411758032,-2.983864589,0.016863656,0.091193137,0.09629697,-0.058390713,-1.8663835290000002,-1.482115114,-1.9595880209999998,-1.862500188,-2.507802994,-2.315713069,-2.629312621,-3.3384165560000003,-0.269042314,-1.097512604,-17.6006721,-14.701102599999999,-20.80925384,-17.02177246,-15.33553066,-20.13570096,-8.090244589,-4.853139804,-14.740161895751953,-12.733449935913086,-13.688994407653809,-13.610118865966797,-15.645055770874023 -4160,4160,I243A,0.065622234,0.07417012,0.08997634199999999,-1.181735294,-2.057418444,0.014191134,0.043586543,0.087657925,-0.024912074,0.092165237,0.056175002,0.073365698,0.106586986,-0.651611478,-1.71185911,-2.012649241,-2.102187646,1.8099466530000001,1.414766885,-10.30169086,-12.31451107,-8.785876099,-8.837180855,-11.41756712,-10.15331918,-5.483169159,-1.9379720409999999,-7.2967681884765625,-8.164199829101562,-8.058180809020996,-8.135564804077148,-8.686976432800293 -4161,4161,I243C,0.065508991,0.088783178,0.058582678,0.009597641,-1.059116701,0.017647977,0.053221397000000004,0.077796584,-0.044899344,0.12750620699999998,0.050060149000000005,0.052110980999999994,0.065054375,-0.008715603,0.027910885,-0.758953125,-1.3592802769999999,1.043947005,1.470494542,-10.66389914,-12.30887901,-9.40971521,-11.06627554,-11.34629003,-9.188335899,-7.057477235,-3.902990463,-10.170061111450195,-12.388096809387207,-9.710681915283203,-10.767985343933105,-12.066946029663086 -4162,4162,I243E,0.010596776,0.055199009,0.0047371240000000005,-1.500954022,-2.4380046159999997,-0.038913062000000005,-0.022565222000000003,0.043758774,-0.022663985,0.10223019900000001,0.008167819,0.08676797300000001,-0.077293726,-1.44625532,-1.5556527230000001,-2.195835317,-2.680173915,1.03330992,0.742310715,-11.11002178,-12.71423007,-9.433608527999999,-11.78301006,-11.96503222,-9.654228027,-5.128931042,1.067602656,-9.448195457458496,-6.411615371704102,-8.5789794921875,-12.187151908874512,-12.821549415588379 -4163,4163,I243D,0.037478648999999996,0.069273607,-0.690027728,-2.004955286,-2.565342048,-0.036323824,0.015904704,0.05905259400000001,-0.071348492,0.039426436,0.099120777,-0.372756662,-1.007298793,-1.978679383,-2.031231189,-2.126199389,-3.0044847060000004,1.411111592,0.7080829129999999,-8.771093701,-9.641717232000001,-6.780879417,-9.736708427,-11.33588622,-6.360277214,-4.984538349,2.980735268,-7.927107334136963,-3.9275779724121094,-6.746122360229492,-9.697081565856934,-12.516404151916504 -4164,4164,I243G,0.043449277,-0.656726809,-2.061737318,-2.372592318,-2.7513086319999998,-0.011737646000000001,0.026099373,0.060799180999999994,-0.00490937,-0.354050959,-0.959402658,-2.16004255,-1.9634320859999999,-2.206777082,-2.538407554,-2.8136895760000002,-2.688927688,0.660499126,-0.347066547,-13.17959777,-15.45428394,-11.97690398,-12.86204861,-14.14493487,-11.45981747,-6.777238499,-2.501576655,-9.252449035644531,-9.630215644836426,-10.174381256103516,-11.081960678100586,-11.386364936828613 -4165,4165,I243F,-0.036396198,0.020919039,0.023807677000000003,-0.15897730300000001,-1.5285328219999998,-0.073707766,-0.048921208,-0.023871187999999998,-0.062669146,0.069878272,-0.028040195,0.023750298,0.023865055,-0.012670095,-0.30528451,-1.5426228030000002,-1.514442841,0.7817656159999999,1.323995183,-7.970815227,-10.08807221,-7.357606613,-8.548718833999999,-7.072960983,-6.786717491,-7.051944519,-4.36075388,-9.0883207321167,-8.866097450256348,-8.80030345916748,-9.035053253173828,-11.052410125732422 -4166,4166,I243H,0.00770152,0.032771047000000005,-0.692595712,-1.755779025,-2.491182057,-0.016622801,-0.011706175,0.027109215,-0.04959073,0.044588067,0.020954026,-0.39788886700000003,-0.987302557,-1.784609638,-1.726948411,-2.171011734,-2.81135238,1.1707611359999999,0.715058381,-10.7512672,-11.56876872,-9.46884922,-12.56076768,-10.41082461,-9.747125755,-6.733645504,-1.9833954409999999,-10.938180923461914,-8.99320125579834,-9.816550254821777,-11.798174858093262,-14.671272277832031 -4167,4167,I243K,-0.035572865,-1.4525577840000001,-1.8964555419999998,-2.493893114,-2.7047948739999996,0.01113251,-0.043800902999999995,-0.027344826000000003,-0.10527840699999999,-1.670686839,-1.234428728,-1.9800562469999998,-1.812854837,-2.40700202,-2.5807842080000003,-2.457612014,-2.951977733,-0.10823725,-1.065455235,-11.83710142,-14.19486761,-9.431663863999999,-11.97578048,-12.03066524,-11.55252988,-8.947197447999999,-7.524563701,-11.778155326843262,-11.98183822631836,-12.709174156188965,-12.504973411560059,-16.149494171142578 -4168,4168,I243M,0.04291108,0.037125802,0.06900585099999999,0.02935891,-1.109995239,-0.028641449,0.05057684,0.03524532,-0.066469587,0.096239836,-0.021988233,0.063475824,0.074535878,0.101519386,-0.042801567,-1.174646018,-1.04534446,0.700773883,1.341121153,-8.295955888,-8.799234001,-7.841176262,-8.811511292,-8.947658599999999,-7.080199287,-8.880794452,-7.311895812,-6.534402847290039,-6.621834754943848,-7.9038848876953125,-7.158492565155029,-9.541448593139648 -4169,4169,I243L,0.040114778999999996,0.068840548,0.073224285,0.013945488,-0.076638868,0.013247662,0.028258303999999998,0.051971254,-0.018048194,0.08542904300000001,0.052252052,0.038278415,0.108170155,0.004113932,0.023777044,-0.056668894000000004,-0.09660884199999999,1.325898485,2.473707264,-4.608048601,-4.2178633880000005,-4.570081276,-5.371840294,-4.816556389,-4.063901657,-5.2709473430000005,-2.301809001,-5.184079647064209,-6.388156414031982,-6.312431335449219,-6.903554439544678,-8.510562896728516 -4170,4170,I243N,0.021870122000000002,-0.004364141,-0.761701438,-2.137489569,-2.7810420419999997,-0.002352431,-0.001547004,0.045287247,-0.031857315,0.022453622000000003,-0.031181904,-0.438886014,-1.084516862,-2.125107035,-2.1498721030000003,-2.652838283,-2.9092458,1.4798569469999998,0.674675713,-7.169994658999999,-8.375653969,-6.240229622,-7.660734131,-7.475560852,-6.097794724,-4.513948793,-0.91189504,-9.031611442565918,-9.30186653137207,-10.143046379089355,-8.988558769226074,-12.643105506896973 -4171,4171,I243Q,-0.045078029000000006,0.012335843999999999,-0.0154672,-1.780074959,-2.610417763,0.007899545,-0.09566188699999999,0.005505829,-0.037903951,0.036352231,-0.011680543,-0.004829987,-0.026104412999999996,-1.724585425,-1.8355644930000001,-2.076225414,-3.144610112,0.690522931,0.687069492,-11.80638272,-13.30653812,-10.25005946,-13.09220164,-10.78431976,-11.59879461,-8.086470935,-4.974837553,-10.142972946166992,-7.455030918121338,-10.012357711791992,-11.825008392333984,-13.531033515930176 -4172,4172,I243P,0.051477898,-1.593185545,-2.230320158,-2.301918801,-2.686522533,-0.00279647,0.026213259,0.076742537,-0.081950753,-1.655464765,-1.530906325,-2.447284261,-2.013356054,-2.12950254,-2.4743350619999998,-2.674962555,-2.69808251,-0.087591647,-1.061373189,-13.5438329,-15.35888942,-13.05350346,-13.50056636,-13.96186192,-11.84434332,-8.947197447999999,-7.524563701,-12.28347396850586,-13.8362455368042,-14.629847526550293,-14.08974552154541,-15.060129165649414 -4173,4173,I243S,0.013539913999999998,0.040877079,-0.936215331,-2.158444828,-2.7778265280000003,-0.002765089,0.00015709399999999998,0.026922734,-0.06904674,0.057538695,0.024215463,-0.570250618,-1.302180043,-1.9502308480000001,-2.366658807,-2.3476283280000003,-3.2080247269999997,1.702379962,0.7668664559999999,-10.75295923,-12.50100073,-10.43171204,-10.67010694,-11.55284229,-8.609134125,-6.919913987999999,-2.979832094,-8.490791320800781,-9.928359985351562,-9.602173805236816,-9.49402904510498,-10.08878231048584 -4174,4174,I243R,0.013166849,-1.329316832,-1.985501269,-2.492894051,-3.5119460260000004,-0.02233366,-0.015959624,0.042293322,-0.070903566,-1.240909277,-1.4177243869999998,-1.956651862,-2.014350676,-2.53486531,-2.450922792,-2.886505299,-4.137386752,0.660023241,-0.715719507,-13.54566162,-14.67477096,-12.78254327,-13.92391099,-13.24186958,-13.10521329,-8.947197447999999,-7.524563701,-11.209827423095703,-11.997888565063477,-12.201644897460938,-11.634305000305176,-15.199536323547363 -4175,4175,I243T,0.034700401,0.043387199999999994,0.07718544,-1.090716959,-1.727102205,-0.045848094000000006,0.012469257,0.056931545,0.004101212,0.058865654,0.027908746,0.050870782999999996,0.103500097,-0.701543817,-1.4798901009999998,-1.779212043,-1.674992367,2.026990105,1.5635715890000002,-9.095602695,-10.35768358,-7.693920609,-8.577382683,-10.36173849,-8.487288109,-6.122047185,-3.114581649,-8.138474464416504,-8.78622055053711,-7.617181777954102,-8.28169059753418,-9.500541687011719 -4176,4176,I243W,0.036021199999999996,0.044776381,0.052939125,-0.902338249,-1.790956755,-0.045507097999999996,0.008129009,0.063913391,0.0013362920000000002,0.065473542,0.024079219,-0.004810122,0.110688372,-0.646135766,-1.158540731,-1.7544518930000002,-1.827461616,1.9481741719999999,1.535148341,-11.71498308,-13.48342937,-11.42175362,-12.19147546,-11.40541675,-10.07284021,-8.947197447999999,-7.5245637,-13.912739753723145,-12.843242645263672,-11.266189575195312,-12.67473030090332,-14.626445770263672 -4177,4177,I243V,0.025321068,0.025203681000000002,0.068278409,-0.022591264,-0.035947545,0.005088205,0.001635023,0.049007112,-0.032580653,0.04322553,0.007181831,0.036820618,0.099736199,-0.029657972,-0.015524556,-0.058302447,-0.013592642,1.233653721,2.383984478,-3.7492432630000003,-4.151168633,-3.834317978,-2.955548965,-4.1958099980000005,-3.609370743,-4.6282772539999995,-1.73228398,-3.954159736633301,-3.059164524078369,-4.738466262817383,-4.918278217315674,-6.154848098754883 -4178,4178,I243Y,0.030213179,0.027129393999999998,0.026286507999999997,-0.07660408,-1.3836478319999999,-0.09815491400000001,0.024000491000000002,0.036425867,0.054430975,0.061747537000000005,-0.007488749,-0.039668065,0.09224108,-0.06284801,-0.090360149,-1.478505304,-1.288790359,0.666937432,1.320370207,-9.338147717,-11.66803503,-8.665228439,-10.23079481,-8.291348976,-7.835331329,-7.536271033999999,-4.698523722,-10.670324325561523,-9.77084732055664,-8.094151496887207,-10.559500694274902,-10.621378898620605 -4179,4179,I244A,-0.007152378,0.015890875,-0.021977887999999998,0.020203052,-1.073623609,-0.007154087,0.005187907,-0.019492663,-0.043698343,0.051190389,-0.019408639,-0.00179777,-0.042158006,0.032808696,0.007597408000000001,-0.654165896,-1.4930813219999999,0.785748695,1.4213444290000001,-5.330614505,-7.073929871,-5.4577110520000005,-5.636134682000001,-3.745444527,-4.739852394,-3.1532906689999995,-0.405714426,-4.141025543212891,-8.648168563842773,-5.76302433013916,-6.100332260131836,-7.5846686363220215 -4180,4180,I244C,0.022641424,0.001546656,-0.031098224,0.040619194,-0.823006157,-0.0489674,0.020656512,0.024626335,0.077993903,0.036028943,-0.032935631,-0.0014413370000000002,-0.060755110999999994,0.023903922,0.057334465,-0.290490035,-1.355522279,1.170555458,1.81393943,-8.82075938,-11.21163763,-9.454452446,-9.642571991,-7.241193375,-6.553941452,-5.659179802000001,-2.59414956,-7.574267864227295,-13.202698707580566,-10.113722801208496,-8.010209083557129,-12.163118362426758 -4181,4181,I244E,0.016434433999999998,-0.644728313,-1.918909803,-2.48572108,-2.880303607,-0.024096356,0.011015863999999998,0.021853004,0.016390416,-0.260257373,-1.029199253,-1.7334835830000002,-2.104336022,-2.689170486,-2.282271674,-2.515447804,-3.2451594089999998,1.15172731,0.016717607,-11.62730782,-13.93446906,-12.45063636,-11.50719923,-10.28237143,-9.961863022000001,-9.082265126,-9.173498397000001,-9.5337553024292,-11.553826332092285,-10.810407638549805,-11.026928901672363,-12.478266716003418 -4182,4182,I244D,0.077135049,-1.534247897,-2.518009859,-2.175049168,-2.7457229539999997,-0.022702572,0.103359905,0.050910193,-0.050150074,-1.5746128469999998,-1.493882946,-2.160878571,-2.8751411460000003,-2.08853675,-2.261561586,-2.215844064,-3.2756018439999997,-0.025506762000000002,-0.996070606,-11.58581791,-14.28138889,-12.26633394,-11.42788671,-9.989764037999999,-9.963715965,-9.109593716000001,-9.367374332,-9.386872291564941,-11.803520202636719,-12.522945404052734,-7.797072410583496,-13.127897262573242 -4183,4183,I244G,0.001152148,-0.062283497,-1.3015287420000001,-2.068622095,-2.384993055,-0.023535357000000003,0.008713865999999999,-0.00640957,0.027617265,-0.019775527,-0.104791467,-1.073995967,-1.5290615159999998,-2.1043164869999997,-2.032927702,-2.263808484,-2.506177625,3.218408153,1.7470941009999998,-10.79211838,-13.30399988,-10.74251078,-10.96663734,-9.227958145,-9.719485764,-6.216840116,-2.7222463,-5.765185832977295,-11.45138168334961,-9.119783401489258,-8.028109550476074,-10.35785961151123 -4184,4184,I244F,0.043547304,-0.004534079,-0.029161945,-1.268914626,-2.43572497,-0.034944849,0.077751729,0.009342878,0.035241372,-0.008531188,-0.000536969,0.016878848000000002,-0.07520273799999999,-1.003646614,-1.5341826369999998,-1.998715953,-2.872733986,2.22480963,1.557580615,-9.703467154,-12.4180079,-10.29370527,-10.69897815,-7.372225693,-7.734418762000001,-6.0681927920000005,-4.065093317,-6.73996639251709,-8.216414451599121,-7.953333377838135,-3.097327709197998,-8.127748489379883 -4185,4185,I244H,0.0037530420000000003,-0.7866783759999999,-2.636017682,-2.244601985,-2.599593889,-0.008844934,0.017166831,-0.009660746999999999,0.037324323,-0.438617871,-1.1347388809999999,-2.200974854,-3.0710605089999996,-2.07748051,-2.411723459,-2.681909079,-2.517278698,0.601104304,-0.412550146,-11.08668098,-13.17637355,-12.00241818,-12.18982189,-8.961529694,-9.103261604,-7.911028932000001,-6.927088599,-10.166231155395508,-12.596311569213867,-11.596460342407227,-8.773500442504883,-13.157299041748047 -4186,4186,I244K,-0.02316096,-1.5458608619999998,-2.4160009330000003,-2.0017064909999998,-3.095259022,-0.108309821,-0.03658313,-0.00973879,-0.013396587,-1.506953515,-1.584768208,-2.5191879719999997,-2.312813894,-1.872814882,-2.130598099,-2.699092201,-3.491425842,-0.025066021,-0.966104585,-11.21553403,-13.69153101,-11.85655478,-11.18525734,-9.484025878999999,-9.860301125,-9.109593716000001,-9.367374332,-10.677238464355469,-12.652168273925781,-12.476627349853516,-11.181960105895996,-14.24599838256836 -4187,4187,I244M,0.004732867,-0.017520999,-0.022535777000000003,0.047888535999999995,-0.239541728,-0.052784062,0.029457992000000002,-0.019992259,0.094683491,-0.028973775,-0.006068223,-0.030251113,-0.01482044,0.054231879000000004,0.041545192,-0.170257648,-0.308825807,1.47996285,2.272949046,-6.47940029,-6.870320037999999,-7.225805115,-7.710339478,-5.894047714,-4.696489105,-5.465041645,-3.0150450139999996,-5.935546398162842,-6.498748302459717,-5.717294692993164,-5.330822467803955,-7.468639373779297 -4188,4188,I244L,0.046837547,0.030961462999999998,0.011056081,0.049687138,-0.235075165,-0.025678896,0.051939384000000005,0.04173571,0.054941923,0.031084577999999998,0.030838347999999998,0.02171899,0.000393171,0.037747623,0.061626652000000004,-0.120817384,-0.349332945,1.46857067,2.446598589,-5.530726764,-7.048837624,-6.882675598,-6.972667191,-3.5730005869999997,-3.17645282,-4.8571294510000005,-2.448799601,-5.037297248840332,-5.854754447937012,-6.0610032081604,-5.393674850463867,-6.300477027893066 -4189,4189,I244N,-0.0013667470000000002,0.008084051,-1.284721924,-2.24855002,-3.3332381669999998,-0.030392407000000003,0.024332696,-0.027066188999999997,0.025841241,0.06904329299999999,-0.052875192,-0.950140023,-1.619303825,-2.318007373,-2.179092666,-2.9224359410000003,-3.744040392,0.5694429,0.11314909,-9.195430228,-11.51191214,-11.37822757,-8.754122459,-6.714432662999999,-7.618456306000001,-6.070973019,-5.441105982000001,-9.090766906738281,-12.131391525268555,-11.623031616210938,-9.108774185180664,-11.904747009277344 -4190,4190,I244Q,0.050085889,-0.592769631,-2.0106955330000003,-2.59640109,-3.141498615,0.013850338,0.054863657,0.04530812,0.030508899,-0.26800979399999997,-0.917529467,-2.1095480230000003,-1.9118430419999999,-2.338236197,-2.854565983,-2.766573507,-3.516423722,0.7266717979999999,-0.260870819,-11.45010705,-14.0516451,-12.35722339,-11.63461196,-9.485426033,-9.721628761,-9.109593716000001,-9.367374332,-9.825389862060547,-12.119004249572754,-10.82401180267334,-9.984895706176758,-12.562695503234863 -4191,4191,I244P,-0.007786819,-1.824367883,-2.21946468,-2.4812614969999998,-3.225329025,-0.007815304,0.011786804,-0.027360441,-0.03921509,-1.7442487430000002,-1.9044870230000002,-2.455453204,-1.983476155,-2.383111383,-2.57941161,-2.811448692,-3.639209358,-0.58165319,-1.094030348,-12.10081551,-14.12447701,-12.96553632,-12.38819677,-10.63211231,-10.39375515,-8.830916916,-8.120035386,-11.05316162109375,-14.727575302124023,-13.04623031616211,-14.255935668945312,-13.589644432067871 -4192,4192,I244S,0.035562922000000004,0.007599284,0.00403651,-1.519546852,-2.244336833,-0.042046263,0.05444075599999999,0.016685088,-0.01085512,-0.00900249,0.024201057999999998,0.023761288,-0.015688268000000002,-0.950795761,-2.088297943,-2.14600331,-2.342670355,2.02707648,1.41150632,-7.911682765,-9.834381706,-8.772996407,-8.505118156,-6.207642365,-6.238275192000001,-6.130250406,-2.296846334,-6.979076385498047,-10.721467018127441,-8.979660034179688,-8.224365234375,-10.71745491027832 -4193,4193,I244R,-0.0008085939999999999,-1.702959251,-1.995138008,-2.350243011,-2.6378856269999997,-0.033758368999999996,-0.00348903,0.001871842,-0.059515648,-1.7712347940000002,-1.634683708,-2.156585675,-1.83369034,-2.31832706,-2.382158962,-2.512581163,-2.7631900910000002,-0.141702847,-1.078846315,-11.99298197,-14.94713016,-13.10632375,-12.14341821,-9.883784149,-9.884253601000001,-9.109593716000001,-9.367374332,-9.36336898803711,-12.772904396057129,-11.94990348815918,-9.67380142211914,-13.669353485107422 -4194,4194,I244T,0.029200261,0.051152921,0.003171942,0.091515372,-1.26337091,-0.05122391900000001,0.035183048,0.023217474,0.009238788000000001,0.07896627,0.023339572000000003,0.014300073,-0.00795619,0.094733094,0.08829765,-0.76383774,-1.76290408,0.595264548,1.3678763109999998,-4.364479523,-5.54005381,-4.788003777,-4.6121778110000005,-2.760399467,-4.121762749,-3.85947255,-2.191479522,-5.971091270446777,-8.809781074523926,-6.339300155639648,-7.369564056396484,-8.694808959960938 -4195,4195,I244W,0.007254213000000001,-1.4891335369999998,-2.026848198,-2.38640492,-3.007136282,-0.022107402999999998,0.024142413999999997,-0.009633989,0.020651806,-1.4891207380000002,-1.489146336,-2.075386462,-1.978309933,-2.7300433689999997,-2.0427664709999998,-2.857350683,-3.156921881,-0.20834207100000002,-0.928859125,-11.85298989,-15.12816426,-13.09668448,-12.31070995,-9.820599876000001,-8.908790886,-6.770993869,-4.318748962,-10.422515869140625,-12.57968521118164,-11.244209289550781,-9.158431053161621,-13.329036712646484 -4196,4196,I244V,0.063351737,0.047562497999999995,0.007922957,0.07763918,0.041399423,-0.026606962,0.062326458,0.064377015,0.068438873,0.035430723,0.059694273,0.02104629,-0.005200376,0.055550563,0.099727796,0.026473977000000003,0.05632486900000001,1.358406575,2.9765883360000003,0.06944684400000001,-0.20368866,0.328452095,0.09578040300000001,0.20087258100000002,-0.074182198,-0.296350994,0.236958621,-2.439457893371582,-4.033421516418457,-2.594135284423828,-4.882034778594971,-4.0880208015441895 -4197,4197,I244Y,-0.017399841,-0.059205373,-1.3136794440000001,-1.9207722109999998,-3.36554001,-0.008005634000000001,-0.027993075,-0.006806606,0.01803603,0.013910292,-0.132321038,-1.142467607,-1.48489128,-2.08901113,-1.7525332919999999,-2.9944696939999997,-3.736610326,0.689531227,0.09432728,-10.384710499999999,-13.83162063,-11.2075121,-10.35086505,-7.809050262,-8.724504471,-5.571866729,-4.047612026,-7.986747741699219,-8.418939590454102,-9.337438583374023,-4.843879222869873,-9.796374320983887 -4198,4198,A245C,0.026716313,0.030424905,0.007611765,0.020032078000000002,-0.134037041,-0.023658857000000002,0.027944385,0.02548824,0.063362729,0.020861148,0.039988662,0.000858547,0.014364983000000001,0.032074187000000004,0.007989969,-0.064102045,-0.20397203600000002,1.271284413,2.378906169,-8.280635352000001,-8.072900391000001,-8.407343369,-7.777071205,-7.5572366870000005,-9.588625107,-7.746832232999999,-5.583922503999999,-8.136076927185059,-10.054115295410156,-9.990411758422852,-8.388290405273438,-10.202550888061523 -4199,4199,A245E,0.052144564000000004,-1.304509822,-2.0636459819999997,-2.549644364,-2.425668012,-0.033795361,0.05629798,0.047991147000000005,0.041503252000000004,-1.382353775,-1.226665869,-2.180048298,-1.947243665,-2.544468712,-2.554820016,-2.640028486,-2.2113075369999997,-0.229231438,-0.86496871,-8.865486498,-9.254937469,-8.337445999,-8.425584236,-8.869430679,-9.440034103,-7.673697889,-5.014784325,-10.051521301269531,-9.572198867797852,-12.147796630859375,-11.554784774780273,-13.011284828186035 -4200,4200,A245D,0.006957808,-1.647670435,-1.908391619,-2.555499648,-2.9315232960000004,-0.040542363,0.01906998,-0.005154364,-0.04347807,-1.880599898,-1.414740972,-1.833196382,-1.983586855,-2.440654844,-2.6703444519999997,-2.837244613,-3.025801978,-0.25912604,-1.1018313290000001,-10.20247545,-10.33106832,-10.15113739,-9.822253212,-10.33091506,-10.37700326,-8.765330151,-7.222716351,-11.220552444458008,-9.63729190826416,-13.201454162597656,-13.61167049407959,-13.466285705566406 -4201,4201,A245G,0.007907824,0.000479785,0.004598097,0.002255979,-0.15004261900000002,-0.01656004,0.004370293,0.011445355,0.015190296,-0.012942094,0.013901664,-0.017010551999999998,0.026206746,0.016755498,-0.01224354,-0.09794520599999999,-0.20214003100000003,1.4439622930000002,2.410744747,-3.663431198,-3.319562141,-2.9188684460000003,-4.413447273,-4.360414604,-3.304863525,-3.954464621,0.433668811,-6.971158027648926,-6.10146427154541,-5.872394561767578,-5.45442008972168,-6.383264541625977 -4202,4202,A245F,-0.008573186,0.001549465,-0.524997786,-2.121180393,-2.347673839,-0.052705999999999996,0.009325418,-0.02647179,0.001853564,0.001055301,0.002043629,-0.20362736,-0.8463682109999999,-1.762480489,-2.479880297,-2.0470964990000002,-2.648251179,1.50475954,0.782130826,-9.570575224,-10.66743808,-10.57867436,-8.785353249,-7.523918472,-10.29749196,-7.751663793,-5.2272882880000004,-9.617321968078613,-10.128242492675781,-12.402189254760742,-10.430821418762207,-13.232561111450195 -4203,4203,A245I,-0.007885645,0.019592134,-0.9960241329999999,-1.908029112,-2.672161135,0.005113625,0.017004637,-0.032775927,0.005290230999999999,0.034540483,0.004643784000000001,-0.616882412,-1.3751658530000002,-1.859968214,-1.95609001,-2.38149672,-2.9628255489999997,2.12363396,0.99153588,-9.952998331,-10.73467154,-11.18321612,-8.322279922,-8.030671814,-11.49415226,-7.364562094,-5.302274699,-6.426386833190918,-6.780055999755859,-9.982995986938477,-8.360654830932617,-10.438352584838867 -4204,4204,A245H,-0.052815544000000006,-1.645760074,-2.3479245580000003,-2.532892944,-3.24953721,-0.063438776,-0.052630434000000004,-0.053000654,-0.050140215999999994,-1.5872341209999998,-1.704286026,-2.685958641,-2.009890474,-2.448319063,-2.617466825,-2.8449088319999998,-3.654165588,-0.042650508,-1.026225934,-10.65694945,-10.56567274,-10.67927341,-9.526103432000001,-9.921352234,-12.59234542,-9.622734055,-9.90718017,-10.614105224609375,-10.978931427001953,-13.405804634094238,-10.018381118774414,-14.72083568572998 -4205,4205,A245K,0.010416909,-1.3264582520000001,-2.4344102380000003,-2.5313329959999997,-2.7083866389999995,-0.019237367,0.036953066,-0.016119248,-0.08534946199999999,-1.2990946159999999,-1.3538218869999998,-2.175970386,-2.69285009,-2.239360804,-2.823305187,-2.334920578,-3.0818526989999997,0.351892091,-0.814459134,-10.57110859,-10.47136937,-10.54830146,-9.505665047,-10.131068800000001,-12.19913829,-9.622734055,-9.907180413999999,-9.650367736816406,-11.278478622436523,-14.645992279052734,-10.675654411315918,-15.296887397766113 -4206,4206,A245M,-0.006193753000000001,0.008081959,0.00342815,-0.769124127,-1.93600713,-0.032434364,-0.012203189,-0.000184316,0.083192423,0.010794393999999999,0.005369523,0.005409625,0.001446675,-0.257211856,-1.281036397,-2.178846432,-1.6931678280000002,1.453140967,1.311852424,-9.470419117999999,-10.19009364,-10.33469344,-9.174012428,-8.288693047,-9.364603035,-7.9353169470000005,-5.63266955,-7.550925254821777,-8.432120323181152,-10.529427528381348,-8.147714614868164,-11.075511932373047 -4207,4207,A245L,0.0019079379999999999,-0.021573192999999997,-0.017939827,-1.660930373,-2.375076616,-0.05711220400000001,0.012932292,-0.009116417,0.018198117,-0.031991857,-0.011154529,0.00219129,-0.038070942999999996,-1.403621809,-1.918238937,-2.285301763,-2.464851468,0.694033511,0.711950767,-9.370869312,-9.577374747999999,-10.22538933,-8.326599075,-7.695923546,-11.02905986,-6.8343540339999995,-4.17936011,-7.370449542999268,-8.627201080322266,-10.405241966247559,-7.481088161468506,-11.426815032958984 -4208,4208,A245N,-0.020302232,-0.669554619,-1.5085353590000001,-2.305665431,-2.405268093,-0.029796603999999997,-0.02384896,-0.016755503,-0.002361808,-0.39509320299999995,-0.9440160340000001,-1.4858487930000002,-1.531221925,-2.590631896,-2.020698965,-2.686191669,-2.124344517,1.6679073469999999,0.21838492,-10.10502652,-10.42772224,-10.03907861,-9.575649025,-9.721446938,-10.76123576,-9.622734055,-9.907180409,-10.19316291809082,-9.877630233764648,-12.215280532836914,-10.434677124023438,-12.58083438873291 -4209,4209,A245Q,-0.091997266,-0.901689009,-1.755091111,-2.6301651180000003,-2.8072187619999998,0.005447181,-0.045806056,-0.138188475,-0.014745194,-0.49401850700000005,-1.30935951,-1.749090227,-1.761091994,-2.2896019,-2.970728336,-2.385161674,-3.229275849,1.731964813,0.156113878,-10.65259162,-10.80267835,-10.3892758,-9.821191688999999,-10.4011254,-11.84868687,-9.622734055,-9.907180967999999,-9.972981452941895,-10.601984024047852,-13.404019355773926,-6.473574638366699,-13.884366989135742 -4210,4210,A245P,-0.016626553,-1.62681056,-2.018825647,-2.308049668,-3.0093595239999997,-0.010792111,-0.01534006,-0.017913046000000002,-0.035187772,-1.6539999930000002,-1.599621126,-1.998706941,-2.0389443519999997,-2.208225395,-2.407873941,-2.7809064230000002,-3.237812625,-0.553613789,-1.06572681,-10.07812543,-9.784262878,-10.37555206,-9.396767159,-10.04391891,-10.79012617,-9.622734055,-9.907181415,-9.311371803283691,-10.768890380859375,-11.555364608764648,-12.174667358398438,-12.417991638183594 -4211,4211,A245S,-0.00017409900000000001,0.006818566999999999,-0.027245197000000002,-0.019631671,-0.090878592,-0.033718448,-0.011889283999999998,0.011541087,0.017490732,-0.002357031,0.015994163999999998,-0.030154687000000003,-0.024335707,-0.009979021999999999,-0.02928432,-0.08091111599999999,-0.10084606800000001,1.3438084190000001,2.373334145,-3.57832469,-3.95941568,-3.8275830539999998,-3.620427284,-2.245999161,-4.238198273,-4.808467641,-3.8787244739999998,-6.846785545349121,-7.625029563903809,-6.533220291137695,-6.705722808837891,-7.063518524169922 -4212,4212,A245R,-0.009630441,-1.5850774109999999,-2.176317519,-2.223843198,-2.617993368,-0.055968687,-0.008950268,-0.010310614000000001,-0.057285422999999995,-1.7387996159999999,-1.431355205,-2.138554131,-2.214080907,-2.063641851,-2.384044545,-2.501624305,-2.734362431,-0.414915417,-1.090991343,-10.03551169,-9.93696907,-9.839323547000001,-9.070546211,-9.57984903,-11.75087059,-8.600917371,-7.222716349,-8.039252281188965,-11.448368072509766,-13.502442359924316,-9.46676254272461,-15.608372688293457 -4213,4213,A245T,0.01883738,-0.000910474,0.003203478,-0.18326693300000002,-1.716790487,-0.007667064,0.06434682,-0.026672061,0.028130814,-0.014890665,0.013069717,-0.020718875,0.027125831,0.016725632,-0.383259498,-1.5097245609999999,-1.923856412,0.638492736,1.3165494340000001,-7.125350983,-7.052668716,-7.42058194,-7.048399483,-6.4140508579999995,-7.6910539170000005,-7.576814111,-6.320433206000001,-6.298388957977295,-6.969435214996338,-7.145505428314209,-7.003918170928955,-8.029315948486328 -4214,4214,A245W,0.008167727,-0.127276629,-1.601351016,-1.8003337640000001,-2.025842414,0.043850062,0.065934498,-0.049599045,0.0049109670000000005,-0.031736615,-0.222816643,-1.773913811,-1.42878822,-1.8373042290000001,-1.763363299,-1.9328640030000002,-2.118820824,1.092962418,0.032650623999999996,-11.59341184,-11.56808339,-12.15293452,-10.82190912,-10.56905411,-12.85507806,-9.622734055,-9.907181365,-10.247945785522461,-9.250693321228027,-13.208614349365234,-12.323997497558594,-14.706937789916992 -4215,4215,A245V,-0.043080262,0.006312356,-0.010974676000000001,-1.119378317,-1.857539899,-0.01964983,-0.02156866,-0.064591863,0.000698814,0.028725379,-0.016100668000000002,-0.00397934,-0.017970011,-0.49706636299999996,-1.741690271,-1.9970321869999998,-1.71804761,1.637455191,1.376704802,-7.380883524,-8.287683456,-8.603614182000001,-6.01974408,-6.131548538,-7.8618273620000005,-6.582933861,-3.0958723160000003,-4.453179359436035,-4.1960906982421875,-7.339967250823975,-6.8573737144470215,-7.727825164794922 -4216,4216,A245Y,0.006988666,-0.307583865,-1.7432949080000002,-2.0959627430000003,-2.698135226,-0.013377301999999999,0.035598535,-0.021621203,0.017926763000000002,-0.144636452,-0.470531277,-1.626577723,-1.8600120919999998,-2.070179383,-2.121746103,-2.387587906,-3.008682546,3.279747216,1.584531584,-11.79245325,-12.34916969,-12.65904759,-10.63697308,-10.02999888,-13.28707699,-9.622734055,-9.907181839,-9.722833633422852,-8.229121208190918,-12.233138084411621,-10.877304077148438,-13.738822937011719 -4217,4217,A246C,-0.038855122,-0.013791643000000001,-0.032680972,-0.033651374,-0.037628876,0.004257053,-0.026815771000000002,-0.050894472999999996,0.02294918,0.040636645,-0.06821993,-0.011661866000000002,-0.053700078,-0.020833962,-0.046468785,-0.006976392,-0.06828136,1.3647520519999998,2.591121225,-7.511261246,-7.4656461489999995,-7.759582602999999,-7.488099564,-7.084003372000001,-7.758974541000001,-8.542404703999999,-6.401769387000001,-6.635169982910156,-9.467945098876953,-8.43358325958252,-7.752764701843262,-8.396281242370605 -4218,4218,A246E,0.027042978999999998,-0.008681236,-0.01446366,-0.637217003,-1.7565584490000001,0.024283676,0.038845352,0.015240605,0.011614873999999999,-0.033132497000000004,0.015770025,-0.053790055,0.024862735,-0.16848054699999998,-1.105953458,-1.798598765,-1.714518133,1.15621781,1.3360150720000001,-7.798163943,-7.294775871000001,-8.26490078,-8.068260445,-7.711608086,-7.651274536,-8.549402723,-6.433542075,-8.118246078491211,-7.3185343742370605,-8.462198257446289,-9.931188583374023,-11.754648208618164 -4219,4219,A246D,-0.026338631,0.003044556,-0.670025332,-1.8528062769999998,-2.60408801,-0.015015526000000001,0.006390761,-0.059068023,-0.041070981,0.018031512,-0.011942399999999999,-0.074032951,-1.266017712,-1.64812323,-2.057489323,-2.298444834,-2.909731185,0.68114755,0.6926753309999999,-8.166625002,-7.620525367999999,-8.423446236,-8.542701225,-7.839656357000001,-8.406795822000001,-8.549402723,-6.433542077,-9.205322265625,-8.167045593261719,-9.88182258605957,-11.60108757019043,-12.173736572265625 -4220,4220,A246G,-0.004841436,-0.003428353,0.0035406920000000002,0.001633932,-1.612438124,-0.01713011,-0.01293235,0.0032494790000000004,-0.030809296,0.018118223,-0.024974927999999997,0.030447767,-0.023366384,0.025425526,-0.022157662999999998,-1.280499254,-1.944376993,0.9151945840000001,1.35749758,-7.1517617,-6.9713293610000004,-6.72309465,-7.250945602000001,-7.153478462000001,-7.6599604260000005,-8.521964203,-6.272064761,-7.111276626586914,-6.739330291748047,-6.817146301269531,-7.830618381500244,-7.536677360534668 -4221,4221,A246F,0.012082878,-0.014821313000000001,0.002246737,0.01790357,-0.031573143,0.001372596,0.013570138999999998,0.010595617,-0.047333824000000004,-0.016652865,-0.012989761,-0.00287935,0.007372824,-0.016472335,0.052279475,-0.06258537,-0.000560916,1.278958819,2.318561243,-3.017167175,-4.045339905,-2.942600014,-3.409385559,-1.573764664,-3.114745735,-3.8982562819999997,1.319550008,-4.347382545471191,-6.419256210327148,-4.570505142211914,-7.476154327392578,-7.485613822937012 -4222,4222,A246I,0.008971914000000001,-0.028538519,0.011916932,-0.000271221,-0.007062572,-0.046142221,0.021550465,-0.0036066379999999997,-0.012070533999999999,-0.022564355,-0.034512682,0.019317251,0.004516612,-0.031894282999999995,0.031351841,0.000530706,-0.01465585,1.338437336,2.636100114,-1.73596864,-1.815357307,-1.5183206480000002,-1.34332769,-1.8523696669999998,-2.150467888,-2.745419317,3.5197197080000002,-2.176724910736084,-4.933807373046875,-3.8557143211364746,-4.954931735992432,-4.639671325683594 -4223,4223,A246H,-0.027854181000000002,-0.019554966,-0.029184063,-0.995243903,-2.532376938,-0.042546123,-0.007470508000000001,-0.048237853,-0.03877869,-0.05729938,0.018189449,0.011881678,-0.070249804,-0.39803123700000004,-1.592456568,-1.961202665,-3.103551211,1.518855483,1.3619623140000001,-6.3779513979999995,-6.546391517999999,-6.648508835,-6.45850312,-5.706768845,-6.529584671,-6.684925819,-2.979100805,-8.491105079650879,-7.694091796875,-6.610297203063965,-9.091612815856934,-11.904935836791992 -4224,4224,A246K,-0.038384532,-0.014214087,0.003907870999999999,-1.440481937,-2.3727348480000003,-0.033192909,-0.061138677999999995,-0.015630385,-0.104960275,-0.024509378999999998,-0.003918795,0.053984575,-0.046168833,-1.197856249,-1.683107625,-2.715270187,-2.030199508,0.794432611,0.7396772979999999,-8.139322398,-8.071451706,-8.502227097,-7.8311148610000005,-8.036897339,-8.25492099,-8.549402723,-6.4335420789999995,-8.222402572631836,-7.749296188354492,-7.288128852844238,-8.085689544677734,-12.246779441833496 -4225,4225,A246M,0.047774317999999996,-0.012291976999999999,0.019714092,0.018304669,-0.000321423,-0.027254141000000003,0.042561798,0.052986838,0.000903551,-0.004261502,-0.020322451000000002,0.023251293,0.01617689,-0.00874292,0.045352257,-0.008986592,0.008343745999999999,1.27680444,2.487647338,-2.066374289,-2.77452105,-1.853202156,-1.950380653,-2.613277054,-1.140490532,-3.70162098,0.47829554799999996,-3.770089864730835,-4.793912410736084,-4.606471538543701,-5.971329689025879,-5.975405693054199 -4226,4226,A246L,0.031707584,-0.0008271789999999999,0.016469642,0.010161871999999999,0.050627818,-0.007193934,0.031206861000000002,0.032208306,-0.013609818999999999,-0.000427395,-0.001226963,0.02460412,0.008335163,-0.024648391000000002,0.044972135,0.039115789,0.062139846,1.079231291,2.779376345,-1.397399016,-1.7467251430000001,-1.282364517,-1.517431068,-1.4705755619999998,-0.969898788,-2.879784822,2.257176808,-1.8351154327392578,-4.259301662445068,-2.909006357192993,-4.516984939575195,-4.9281697273254395 -4227,4227,A246N,0.004754704,0.030959726,0.020177208999999998,-0.10577875800000001,-2.121236944,-0.037931134,-0.005398292,0.014907698999999998,0.005798157,0.103565233,-0.041645781,0.070730533,-0.030376116,0.039342185,-0.25089970100000003,-1.532192807,-2.71028108,0.44791524899999996,1.307913145,-8.047341643,-7.771866692000001,-8.177812416,-7.812602646,-7.7031547929999995,-8.771271667,-8.064182574,-4.532428956,-8.524255752563477,-7.862053871154785,-9.105779647827148,-9.329193115234375,-11.451112747192383 -4228,4228,A246Q,-0.026453234,-0.011062802,0.00984068,-0.18298975899999997,-1.3833122830000002,-0.021267794,-0.048775905999999994,-0.004130561,-0.050459198,0.019378557,-0.041504161,0.068240937,-0.048559577,-0.044861205,-0.321118313,-1.4041442119999998,-1.362480353,0.702965446,1.3262142670000001,-7.636120428,-7.498932892000001,-7.809017715,-7.318815285,-7.85588945,-7.6979467999999995,-8.549402723,-6.4335420789999995,-7.678472518920898,-5.7776899337768555,-7.202828884124756,-8.582809448242188,-11.351308822631836 -4229,4229,A246P,0.026894836000000002,-1.165469766,-1.84631407,-2.177271696,-2.633705164,-0.004090843,0.035144679,0.018644993000000002,-0.010389496,-0.952730851,-1.378208681,-1.867324903,-1.825303237,-2.142468137,-2.212075255,-2.5643104119999998,-2.703099915,3.369627491,1.3067817659999998,-7.814902162,-7.73005352,-8.289153969,-7.849309959,-7.613791565,-7.592201797,-8.549402723,-6.433542077999999,-7.7191925048828125,-9.876821517944336,-9.265528678894043,-11.654033660888672,-10.439056396484375 -4230,4230,A246S,0.024594902999999998,-0.012990936000000002,-0.007595135,-0.007267241,-0.25935693600000004,-0.022867084,0.033337423,0.015852381999999998,-0.03315398,-0.022794032000000002,-0.003187839,-0.00061581,-0.01457446,-0.036680393,0.022145912,-0.132649009,-0.386064863,1.293853984,2.16233844,-6.666760973,-6.552632065,-6.04568029,-6.307207161,-6.192758682000001,-8.235526665,-8.549402723,-6.433542077,-6.336698532104492,-5.968532562255859,-6.397644996643066,-6.249410152435303,-7.2176008224487305 -4231,4231,A246R,-0.014371983,-0.018896976,-0.91153526,-1.986564,-2.565881715,-0.029488944,-0.018339031000000002,-0.010404934000000001,-0.017091376999999998,-0.013750861000000001,-0.02404309,-0.389652513,-1.433418006,-1.978311454,-1.994816545,-2.403180184,-2.728583245,1.483306379,0.714785115,-6.652902425,-6.215869789,-6.9298059389999995,-6.33717366,-6.699486778,-7.0821759570000005,-6.5883090289999995,-2.48619131,-8.02123737335205,-6.422704696655273,-5.1347527503967285,-7.615849494934082,-12.376775741577148 -4232,4232,A246T,0.005329401,-0.007641452,-0.022717636,-0.020290119,-0.031454708,-0.002723244,0.001670223,0.008988579,-0.024067087,-0.031038932999999998,0.015756028999999998,-0.01588241,-0.029552862000000003,-0.049581339,0.009001101,-0.03940328,-0.023506136,1.396660159,2.52588199,-4.589915735,-4.5441883469999995,-4.431337479,-4.340063011,-4.435207191,-5.198782646000001,-5.979224138999999,-1.95932159,-4.687236785888672,-5.493513107299805,-5.199272155761719,-5.757040977478027,-6.154438018798828 -4233,4233,A246W,-0.010950095,-0.011612023,-0.007504243000000001,-0.255592639,-1.7332458780000002,0.058050733,0.001473744,-0.023373933,-0.063525234,0.015244191,-0.038468236,-0.012244113999999999,-0.002764371,-0.061803127,-0.44938215,-1.6140743380000002,-1.8524174180000001,0.8575666129999999,1.324697695,-6.535964009,-6.931611877000001,-7.341641151,-5.85939563,-5.241808075,-7.305363312000001,-6.226937931,-1.63400786,-7.633936882019043,-6.239173889160156,-3.850001335144043,-9.727861404418945,-9.951286315917969 -4234,4234,A246V,0.004073374,-0.001290251,0.006471136,0.0011163689999999999,-0.0077652419999999995,-0.015179048999999998,-7.159999999999999e-05,0.008218346999999999,-0.012324765,0.004896008,-0.00747651,0.026326036,-0.013383765,-0.016132378,0.018365116,-0.011959583999999999,-0.0035709,1.671448915,3.643209181,-0.329735574,-0.6758471070000001,-0.356700203,0.19301938600000002,-0.517170799,-0.291979149,-1.943826529,3.353556769,-1.2631340026855469,-3.6463608741760254,-2.7271499633789062,-3.453054904937744,-3.1570897102355957 -4235,4235,A246Y,0.011777721000000001,-0.041966456,-0.033315704,-0.006574174,-0.043324547000000005,-0.016667044,0.038109062,-0.014553621000000001,-0.041116828,-0.029941182,-0.053991729,-0.060464471,-0.006166937,-0.048859438,0.035711091,-0.055728365999999994,-0.030920727999999998,1.353146455,2.43625927,-5.631475527999999,-5.947253494,-6.038446205,-6.298144043,-3.983272224,-5.8902616729999995,-5.838548092000001,0.41579707,-6.090303421020508,-5.8052263259887695,-4.973598480224609,-8.664615631103516,-8.468830108642578 -4236,4236,L247A,-0.029964273,0.012110365,0.010283386,-0.457632075,-2.228504933,-0.013562013999999999,-0.048564822,-0.011363723000000001,0.023522535,0.014653706,0.009567023000000001,0.005380541,0.015186231000000001,-0.079262033,-0.836002116,-1.615757501,-2.841252364,0.7970522320000001,1.319448964,-3.909182695,-3.6418026119999998,-4.571821503,-2.872160446,-3.819488106,-4.640640808000001,-4.704781987,-0.475673269,-5.8380231857299805,-6.883560657501221,-5.458364486694336,-6.9777398109436035,-6.439082622528076 -4237,4237,L247C,-0.014202751999999999,-0.0009237560000000001,0.020087752,0.008728353000000001,-1.4721740019999998,0.005297491,-0.031975476,0.0035699720000000002,0.059406836,0.010142481,-0.011989993000000001,0.011998399,0.028177103999999998,-0.016323913,0.033780618,-1.181100569,-1.7632474340000002,0.7282868379999999,1.342885724,-8.094891953,-7.6694207,-9.255341255,-7.882702431,-7.594463165,-8.072532211,-6.768621735,-4.509640476,-6.879133701324463,-8.703246116638184,-8.17411994934082,-8.780683517456055,-8.453390121459961 -4238,4238,L247E,-0.043397088,-0.259243406,-1.786156976,-1.956403612,-2.477048234,-0.08935356900000001,-0.060677058,-0.026117117000000002,-0.056184059,0.020275037,-0.5387618479999999,-1.306560041,-2.26575391,-1.6627866040000001,-2.25002062,-2.129038914,-2.825057554,3.871444323,2.449355039,-11.06060649,-10.19148691,-12.20202135,-10.73286736,-10.83952029,-11.33713656,-9.155121949,-8.850971648,-7.494093894958496,-9.048711776733398,-8.19387435913086,-8.830809593200684,-11.865703582763672 -4239,4239,L247D,-0.048530439,-1.6335809780000001,-1.669960766,-2.101646775,-2.845870413,0.034222543,-0.033974074,-0.06308680400000001,-0.049369885,-1.8660058780000002,-1.401156078,-1.371837206,-1.968084326,-2.074851255,-2.128442295,-2.4441935519999998,-3.247547273,-0.38813607,-1.097039864,-11.53604135,-10.78815274,-13.05423653,-11.28852618,-10.80144897,-11.74784235,-9.155121949,-8.850971648,-8.278488159179688,-9.68504524230957,-8.689573287963867,-10.584439277648926,-12.274347305297852 -4240,4240,L247G,-0.069727836,-0.65892261,-1.9501453340000001,-2.287564063,-2.816725355,0.003824348,-0.07869287900000001,-0.060762792999999996,0.012468232,-0.317410523,-1.000434697,-2.032756866,-1.8675338019999999,-2.165895607,-2.409232518,-2.649181257,-2.984269452,1.005189251,-0.167189514,-8.614614087,-8.708124947,-9.993940224,-7.682692459,-7.120361679,-9.567951126,-6.192105387000001,-3.85984005,-7.679093837738037,-8.944694519042969,-8.003397941589355,-9.820134162902832,-9.201658248901367 -4241,4241,L247F,-0.097075138,-0.000980091,-0.019594489,-0.577659555,-1.8005683190000001,0.028884324,-0.072418357,-0.12173191800000001,-0.003169463,-0.025593461,0.023633279,-0.06706409,0.027875112999999997,-0.11739236199999999,-1.037926748,-1.830565103,-1.770571535,0.979980075,1.319224157,-4.509706436,-4.618375702,-6.211122528,-4.5062680969999995,-3.579907196,-3.632858658,-4.5193604380000005,-1.1133314570000001,-2.712064743041992,-4.501669406890869,-2.3401429653167725,-5.5861663818359375,-1.6141467094421387 -4242,4242,L247I,0.046092954000000005,0.09028587699999999,0.027773269,-0.012085928000000001,0.045515109000000005,-0.029093467999999997,0.040396100000000004,0.051789808,0.054221714000000004,0.083458057,0.097113696,0.025004712000000002,0.030541825,0.010950877,-0.035122732000000004,0.072054614,0.018975603,1.006988195,2.82730381,-1.038436964,-1.283041382,-2.257757034,-0.514259315,-0.47469912,-0.6624279710000001,-3.194412114,0.534409669,-3.572967052459717,-3.6141252517700195,-2.113171339035034,-3.589224338531494,-2.38413143157959 -4243,4243,L247H,-0.05424543,-0.49541200799999996,-1.75074287,-2.483458875,-3.004103497,0.062694606,-0.06580892099999999,-0.042681939,0.050504607,-0.133919863,-0.856904153,-1.741498265,-1.759987474,-2.541422328,-2.425495421,-2.609734629,-3.398472364,0.89970387,-0.007239103,-11.56986987,-9.407322784,-13.42249461,-11.55109064,-11.01786635,-12.45057494,-9.155121949,-8.850971648,-5.92625093460083,-7.509158134460449,-6.186228275299072,-7.507944107055664,-8.871328353881836 -4244,4244,L247K,-0.004992575,-1.264236336,-2.2893785230000003,-2.420034537,-2.091194156,-0.042449803,0.0034313629999999998,-0.013416513,0.025425813999999998,-1.184069213,-1.3444034580000002,-2.070111783,-2.508645263,-2.171065841,-2.6690032319999997,-2.239378142,-1.94301017,0.203603678,-0.7349031540000001,-10.94370031,-10.00024883,-12.54662573,-10.42992614,-10.02161974,-11.72008111,-9.155121949,-8.850971648,-5.666725158691406,-7.268793106079102,-5.413333415985107,-6.805272102355957,-9.02454948425293 -4245,4245,L247M,-0.05038785900000001,0.035729343999999996,-0.07620875,-0.037459542,0.046639438,-0.01368382,-0.006490944,-0.094284774,0.0046119279999999995,0.095794103,-0.024335416000000002,0.019646185,-0.172063684,0.052624749000000005,-0.127543833,0.102880002,-0.009601126,1.130958758,2.8360434089999997,-2.402793707,-2.565386604,-2.479818283,-2.468709793,-2.045446762,-2.454607094,-3.980924785,-2.098778888,-4.385558128356934,-3.541964530944824,-4.548027038574219,-5.64625883102417,-5.25355339050293 -4246,4246,L247N,-0.086416069,-1.302444277,-1.990281135,-1.750755804,-2.593126764,0.022387656000000002,-0.114006804,-0.058825333,0.08261434,-1.130823701,-1.474064852,-2.016866271,-1.9636959980000002,-2.117820329,-1.3836912780000001,-2.18613263,-3.000120897,3.8173601130000003,1.648728583,-10.81016592,-10.12227948,-11.77259896,-10.76317669,-10.23701371,-11.15576077,-9.155121949,-8.850971648,-7.2709503173828125,-7.827934741973877,-7.286397933959961,-8.406993865966797,-10.020751953125 -4247,4247,L247Q,-0.057797797000000005,-0.062653949,-1.54141911,-2.634214766,-2.566813759,-0.074259546,-0.07785665900000001,-0.037738935,0.061648382,0.004646267,-0.129954165,-1.316319878,-1.766518341,-2.496455182,-2.77197435,-2.2637374880000003,-2.8698900289999996,0.542034365,0.05795784599999999,-10.54642649,-9.869404686000001,-11.37236807,-10.63517986,-9.517071547999999,-11.33810826,-9.145504072,-8.785018815,-6.381901264190674,-7.091101169586182,-6.581777572631836,-7.062713623046875,-9.954395294189453 -4248,4248,L247P,-0.060855755,-0.869438465,-1.7533471580000002,-2.00454277,-2.202595062,-0.029615591,-0.061775593,-0.059935917000000005,0.01160054,-0.599701871,-1.139175058,-1.7164869040000001,-1.790207411,-1.957619665,-2.051465875,-2.0928787559999997,-2.312311367,4.261369202,2.445845369,-10.70571882,-10.09790717,-11.57025111,-10.39463721,-10.38361152,-11.08218707,-9.155121949,-8.850971648,-4.012585639953613,-9.029953002929688,-6.60986852645874,-9.06666088104248,-10.228218078613281 -4249,4249,L247S,-0.0016737229999999998,-0.02605746,-1.234897092,-1.9571133330000001,-3.157485965,-0.040440994,-0.016704232,0.013356786,0.034982656,-0.023147735,-0.028967185,-0.921627621,-1.5481665619999998,-1.946064824,-1.9681618419999998,-2.429350474,-3.8856214560000004,2.200343237,0.94216039,-9.199146411000001,-9.134909332000001,-9.726421593,-8.877574447999999,-8.822039436,-9.434787247000001,-8.40637304,-6.253445107,-6.307236194610596,-6.477566719055176,-6.57286262512207,-7.710168361663818,-7.98543119430542 -4250,4250,L247R,-0.062931721,-1.528493684,-2.052890538,-1.988923589,-2.478849363,-0.034273154,-0.064490761,-0.06137268,0.011497916,-1.598710848,-1.458276519,-2.419812611,-1.685968464,-2.094797937,-1.88304924,-2.4641402340000003,-2.493558492,-0.587671425,-1.039479026,-11.41004197,-10.68116383,-11.96905318,-11.28383128,-10.659224400000001,-12.45693716,-9.155121949,-8.850971648,-4.83964729309082,-5.176364898681641,-5.8799543380737305,-5.6527862548828125,-9.11623764038086 -4251,4251,L247T,-0.041101847999999996,-0.01539265,-0.012122843000000001,-0.022290192,-1.595811523,-0.015417462,-0.063913841,-0.018289855,0.048392522,0.012907749,-0.043693048,-0.018631615,-0.00561407,-0.025523502000000003,-0.019056881,-1.177612801,-2.014010245,0.736709026,1.345276163,-5.652886406,-5.3820952,-6.685633507,-5.081616783,-5.3270155180000005,-5.7880710220000005,-4.711481597,-2.367119789,-5.450244903564453,-5.223038673400879,-5.200637340545654,-6.448861122131348,-6.6511616706848145 -4252,4252,L247W,-0.060791867,-0.081425194,-0.031796054,-0.082409111,-1.617789559,0.012270484,-0.025115709,-0.096468025,0.056476544000000004,-0.051137285,-0.11171310300000001,-0.039053287,-0.024538821000000002,0.013482848,-0.17830106899999998,-1.4098048719999998,-1.825774246,0.60156222,1.319371867,-10.00818463,-9.145144646,-11.9610024,-9.720297096,-9.150637779,-10.06384121,-7.764980506000001,-5.192655301,-2.5972228050231934,-2.1614668369293213,-6.155353546142578,-8.099414825439453,-6.015523910522461 -4253,4253,L247V,-0.035773035,-0.024431507999999998,-0.01884707,-0.039030294,-0.031333964,0.005880531,-0.027881087000000002,-0.043664983,0.019649913,-0.034952963,-0.013910053,-0.037154714,-0.000539426,-0.041088406,-0.036972181,-0.057072827,-0.0055951,1.31939238,2.426049301,-1.7905767430000001,-0.617960495,-2.96288414,-1.630470154,-1.774779198,-1.966789726,-2.7825877739999996,1.057655568,-4.603002071380615,-4.531917572021484,-3.527947425842285,-4.684704303741455,-4.00152063369751 -4254,4254,L247Y,-0.020940984,0.059855236,-0.200521927,-1.486413716,-2.78760903,-0.031000688999999998,-0.0052586759999999995,-0.036623291,0.076829504,0.055886534,0.063823938,-0.08891686900000001,-0.312126985,-1.169349259,-1.803478173,-2.351604913,-3.223613147,1.036241985,0.779264415,-8.228036693,-6.216832405,-11.59725136,-7.837054183999999,-7.731956291,-7.757089226000001,-5.00301725,-3.249191319,-2.636964797973633,-5.04788064956665,-3.9523158073425293,-6.726924896240234,-3.918436050415039 -4255,4255,G248A,-0.020177845,7.55e-05,-0.12603547,-1.5442891909999998,-2.338369499,0.016345092,-0.033751002,-0.006604688,-0.053061644000000005,-0.017471102,0.017622123,-0.051887130999999996,-0.20018380800000002,-1.304717014,-1.7838613680000002,-2.1828260619999997,-2.493912936,0.353470351,0.701986042,-6.154536302,-6.4191538239999995,-4.604703667,-5.499897728,-8.292023308,-5.956902985,-6.069141191,0.135368199,-2.9907450675964355,-3.8034634590148926,-2.775428056716919,-3.1549103260040283,-5.2665300369262695 -4256,4256,G248C,-0.00215753,-0.061574184000000004,-1.319188816,-2.200912921,-2.276509166,0.006703817,-0.016371437,0.012056378000000001,-0.04089358,-0.01225679,-0.110891578,-0.982963053,-1.655414578,-2.194764287,-2.207061555,-2.408880913,-2.144137419,1.948764074,0.697703965,-8.942540142999999,-9.365344406,-8.414338821,-8.495728432,-10.24019026,-8.197098793,-7.109318026,-1.467607963,-8.206457138061523,-6.336709022521973,-8.209839820861816,-5.34414005279541,-11.366545677185059 -4257,4257,G248E,-0.009770056,-1.0468448190000001,-1.7607896459999999,-2.004282849,-2.0217645,0.05060585,0.006549049,-0.026089161,0.048645137000000005,-0.7948993259999999,-1.298790312,-1.736668996,-1.784910295,-1.998636839,-2.009928859,-1.9372775740000001,-2.106251425,4.299227179,2.408867543,-7.026289512999999,-9.268737885,-5.599913757,-4.952293274,-8.429235756,-6.881266891,-5.778276647,2.1079617109999997,-4.2967119216918945,-6.876065254211426,-5.108682632446289,-4.742066383361816,-7.115508556365967 -4258,4258,G248D,0.004725838,-0.17175427399999998,-1.5045250380000001,-2.035302703,-2.467998155,-0.010500608,-0.031037426,0.040489102,0.017426856,-0.05372280000000001,-0.289785748,-1.282500626,-1.72654945,-1.8832870259999999,-2.187318379,-2.562290451,-2.373705859,2.755090876,1.274723937,-9.407323853,-11.04365467,-8.390716125,-7.369265121000001,-10.28331835,-9.949664992999999,-6.449675096,1.091934785,-5.1509246826171875,-6.5071330070495605,-5.282554626464844,-6.686923027038574,-8.605366706848145 -4259,4259,G248F,-0.003476073,-0.36182351700000004,-1.6463530830000002,-2.316307975,-2.9622858689999996,0.015713348999999998,-0.022047168,0.015095023,0.017095171,-0.10029065599999999,-0.623356377,-1.495132831,-1.797573335,-2.706934065,-1.925681885,-2.54083945,-3.383732287,0.814595485,0.045374607000000004,-9.414263814,-8.927387589,-7.505537628,-9.257241264,-11.842495800000002,-9.538656784,-4.602923946000001,1.8298097480000002,-5.781576156616211,-4.787204265594482,-5.664989471435547,-3.3760859966278076,-10.379764556884766 -4260,4260,G248I,0.047318026,-0.931757165,-2.112793349,-2.3857754819999997,-2.2749781159999998,0.040800006,0.058977422,0.03565863,0.004847666,-0.7751119470000001,-1.088402382,-2.098222364,-2.127364334,-2.163895561,-2.6076554030000003,-2.599860938,-1.9500952930000002,0.901266067,-0.516491224,-7.491509612000001,-6.747448906,-5.267815186,-7.436018913,-8.52512384,-9.481141212,-5.105059488,0.23613401899999997,-5.698622703552246,-6.14708948135376,-4.741123199462891,-4.625299453735352,-9.569164276123047 -4261,4261,G248H,-0.003232725,0.044930621,-0.001345667,-1.660893582,-2.811644134,0.021351475,-0.033199325,0.026733876,-0.00852285,0.035408597,0.054452644,0.025374095,-0.028065429,-0.914940555,-2.406846608,-2.189755022,-3.433533245,1.955867671,1.370507963,-8.339643365,-8.350147491,-6.931704407000001,-7.5951158979999995,-10.61446922,-8.206779816000001,-6.1652006660000005,0.11198201,-5.049596786499023,-4.430482387542725,-4.490181922912598,-3.750800371170044,-8.424182891845703 -4262,4262,G248K,0.00109662,-0.09097734199999999,-1.3487460619999998,-1.9718327340000001,-3.0922343660000005,0.02696065,-0.005795911999999999,0.007989151,-0.04775034400000001,-0.020108731,-0.161845952,-1.071937856,-1.6255542669999998,-2.091853564,-1.8518119030000002,-2.7039101989999996,-3.480558532,2.200772844,0.872783103,-7.792364645,-7.951387512,-6.387075684,-7.2768956220000005,-9.028849007,-8.317615402000001,-6.0504582010000005,0.446226965,-3.392220973968506,-4.118297100067139,-2.069363594055176,-3.2285664081573486,-6.001500129699707 -4263,4263,G248M,0.002086932,-0.484316157,-2.122213996,-2.314234978,-3.118625003,0.010267271,-0.020849737,0.0250236,-0.015496488999999999,-0.178471223,-0.790161091,-2.22075503,-2.023672961,-2.462519487,-2.165950468,-2.5974548680000002,-3.6397951369999997,0.416306975,-0.33691998799999995,-8.864130396,-7.796717041,-6.834719925,-9.844347313,-9.374752578999999,-10.47011512,-5.77731895,-0.528918247,-5.256106376647949,-4.010746479034424,-4.635553359985352,-4.0071001052856445,-8.41136646270752 -4264,4264,G248L,-0.012250522,-1.214422065,-2.081868533,-2.207003723,-3.208285772,0.023227092999999997,-0.035808458,0.011307415,-0.022138335,-0.998764955,-1.430079175,-2.1897329819999998,-1.9740040840000002,-2.1828555130000002,-2.231151933,-2.9546129910000003,-3.461958553,0.629656282,-0.610327155,-8.679496524,-7.212098877000001,-7.014086128,-8.26454306,-9.543995331,-11.36275922,-4.434664553999999,0.8837610370000001,-4.362958908081055,-3.2638537883758545,-3.1654770374298096,-2.8195126056671143,-8.226001739501953 -4265,4265,G248N,-0.064752308,0.012548907,-0.11777682699999999,-1.892474152,-2.968898199,-0.016044719,-0.0799957,-0.04950891599999999,-0.023088532000000002,0.034147944,-0.00905013,0.050985589000000005,-0.28653924199999997,-1.502028029,-2.282920275,-2.482061449,-3.455734948,0.538745785,0.6958540209999999,-9.146227632,-9.975694366,-8.560578528999999,-8.697232277000001,-9.816987198,-8.68064579,-6.183730493,0.723134443,-4.234638214111328,-4.673326015472412,-4.752723693847656,-5.150856971740723,-8.013497352600098 -4266,4266,G248Q,-0.058969575,-0.321495676,-1.573450693,-2.189131425,-2.82691411,0.054314188,-0.06559867900000001,-0.052340471,-0.055906349,-0.07597924,-0.567012112,-1.4797455880000001,-1.667155798,-2.08948683,-2.28877602,-2.8264822019999998,-2.827346018,0.902334284,0.055703275999999996,-6.1547509510000005,-6.7251492310000005,-5.223781334,-5.251512665,-7.356614532,-6.216696991,-5.51021716,0.625256546,-4.186973571777344,-4.506593704223633,-3.2126314640045166,-3.4492509365081787,-7.077049255371094 -4267,4267,G248P,-0.010249036,-1.6722108740000001,-2.048928412,-2.372155148,-3.3193927000000003,0.004158917,-0.029869173,0.009371101,-0.11344488900000001,-1.74130084,-1.6031209080000002,-2.049852537,-2.048004287,-2.188076402,-2.556233893,-2.820336423,-3.818448977,0.054915625999999995,-1.080016205,-10.62480688,-10.61881342,-9.436379898,-9.777303024,-12.72000624,-10.57153182,-8.206136964,-2.44071098,-1.7689552307128906,-5.499658107757568,0.9570789337158203,-3.182288885116577,-6.785013198852539 -4268,4268,G248S,-0.029739677000000003,-0.016820368,-0.05410371,-1.533001036,-2.356738345,0.028331527000000002,-0.041062452,-0.018416902,-0.037630034,-0.008555874,-0.025084861,-0.009830591999999999,-0.09837682699999999,-1.19416312,-1.871838951,-2.373302164,-2.340174525,0.6059375579999999,0.7206050820000001,-6.255957784,-5.608257903999999,-6.309202415,-5.85840493,-8.603635376,-4.900288292,-4.961587066,0.583989336,-3.49408221244812,-2.7626187801361084,-3.7715723514556885,-3.065534830093384,-5.987715721130371 -4269,4269,G248R,-0.025318399,-0.019303156999999998,-1.213143885,-1.9939185419999998,-2.4059675080000003,0.015247041999999999,-0.048178433,-0.0024583639999999998,-0.040672639,0.023404957999999997,-0.06201127099999999,-0.887325633,-1.5389621359999999,-1.8306842380000001,-2.157152845,-2.103922317,-2.708012698,3.546397689,2.23131895,-5.249103955,-4.862978706,-4.418665466,-4.491831008999999,-7.355614417999999,-5.116430176000001,-4.600007878,1.282242025,-3.7265045642852783,-3.0335724353790283,-1.8936667442321777,-1.8996856212615967,-6.904139041900635 -4270,4270,G248T,-0.006037865999999999,-0.470562315,-1.9652026219999998,-2.106564038,-3.06367362,0.04443157,-0.004611275,-0.007464457,-0.003186622,-0.15020472599999998,-0.7909199029999999,-2.111804399,-1.818600845,-2.126325075,-2.086803001,-2.9144729689999997,-3.2128742710000004,0.581349527,-0.22706669899999998,-5.679486687000001,-5.52503508,-3.9178027269999998,-5.460523705,-8.758514862,-4.73555706,-4.396135467,2.276019147,-3.957646608352661,-2.585247039794922,-3.7268450260162354,-3.7780392169952393,-6.48310661315918 -4271,4271,G248W,-0.046069287,-0.035351886,-1.163058568,-2.187765798,-2.5157898640000003,0.021786253,-0.059384295,-0.032754278,-0.03269935,0.010082648,-0.080786419,-0.84814097,-1.477976165,-1.940143107,-2.435388489,-2.580228466,-2.451351261,2.084947253,0.895574998,-6.358588025,-6.466692329,-7.02859671,-5.171717918,-9.771783997,-3.35414917,-3.2209097989999997,3.15904239,-5.593208312988281,-0.40745359659194946,-5.110408782958984,2.1233325004577637,-10.738512992858887 -4272,4272,G248V,-0.03305388,-1.000011231,-2.010858701,-2.1749302040000003,-2.830067718,0.008257405,-0.051169183,-0.014938576,0.016773695,-0.716668214,-1.2833542470000001,-2.053618614,-1.968098787,-2.1192918119999997,-2.230568595,-3.1292884560000003,-2.53084698,1.1549109359999998,-0.34254151899999996,-7.955326802,-7.48012603,-5.503853027000001,-7.3649894179999995,-10.20109015,-9.226575386,-5.722703479,0.14531326,-5.091876029968262,-6.078205585479736,-4.280423164367676,-3.981454610824585,-8.374789237976074 -4273,4273,G248Y,-0.010458871,-0.245343247,-1.530777927,-2.418984521,-2.8404161489999997,0.036971647999999996,-0.013147918,-0.007769823,-0.040195387,-0.020542809,-0.470143684,-1.431608396,-1.6299474569999999,-2.0413496380000002,-2.7966194030000002,-2.079375006,-3.6014572910000004,3.9388463369999998,2.361626136,-8.750681474,-9.60867231,-6.731304778999999,-8.644083611000001,-10.9171835,-7.85216317,-3.335030562,2.147633682,-5.72202205657959,-3.753401279449463,-5.522970199584961,-2.5917766094207764,-9.705343246459961 -4274,4274,P249A,0.027463187000000003,0.018360498,-0.009839366,-0.001992438,-0.5783242510000001,-0.040891367000000005,0.014584032,0.040342342,0.016375635,0.01057239,0.026148605,-0.016629022,-0.0030497090000000003,-0.013484262,0.009499387,-0.298469166,-0.858179336,1.353395209,1.912290501,-3.640234224,-3.521347122,-3.187146568,-3.52513549,-3.6329701919999997,-4.334571747,-4.398757885,-1.442033785,-6.462036609649658,-5.453544616699219,-6.623675346374512,-6.232614040374756,-6.717013359069824 -4275,4275,P249C,-0.018637671,-0.007107166999999999,-0.032167984,0.02083007,-1.200239393,0.001129808,-0.020940726,-0.016334615,0.040035404,-0.044096707,0.029882374,-0.05251465599999999,-0.011821311000000001,-0.014901174,0.056561314,-1.118172977,-1.2823058090000001,0.848274813,1.364160944,-8.763224187,-8.203470047,-9.524136283999999,-8.042903946000001,-8.417202652,-9.628408005,-7.888805541,-4.820274008999999,-11.867776870727539,-9.8514404296875,-12.298645973205566,-10.804119110107422,-12.909734725952148 -4276,4276,P249E,-0.052040973,0.016823026,-0.026175775,-0.018463989,-0.668956032,0.089514434,0.014668513000000001,-0.118750459,-0.08375613900000001,-0.021133059,0.054779111,-0.041442098,-0.010909452,-0.08200175700000001,0.04507378,-0.453559765,-0.884352299,1.537695302,1.908538703,-6.841610875,-6.719674065,-7.006441841,-5.979129692000001,-6.703627357,-7.799181419,-7.323274277,-4.74577004,-7.472965240478516,-6.481184959411621,-7.5292558670043945,-7.391246318817139,-7.800146579742432 -4277,4277,P249D,-0.08128052599999999,-0.004573971,-0.031232138,0.023382083999999997,-1.041499991,0.0019526110000000001,-0.006702164,-0.155858887,-0.030489705,-0.012988342,0.003840401,-0.024677587999999997,-0.037786688,-0.001699355,0.048463522,-0.631867109,-1.4511328730000002,0.588675896,1.383666835,-5.916577115,-6.411473846,-5.703488342000001,-5.516362419,-5.878126915,-6.0734340520000005,-6.325639288,-3.8279198969999997,-8.259857177734375,-7.115637302398682,-8.265433311462402,-8.04430103302002,-8.463521957397461 -4278,4278,P249G,-0.025055623,-0.01026121,0.006090111,-0.502201031,-1.611388635,0.015462711,-0.027995316,-0.02211593,0.008017338,0.001660784,-0.022183203999999998,-0.019979331,0.032159553,-0.090174097,-0.9142279640000001,-1.6040322969999998,-1.618744973,0.891579346,1.330430316,-5.4691526470000005,-5.5425874020000006,-4.754764755,-5.218153435,-5.394146912,-6.436110733,-5.171776482,-2.114497329,-8.256525993347168,-7.242571830749512,-7.841703414916992,-7.7388129234313965,-8.265238761901855 -4279,4279,P249F,-0.121307136,-0.035532408,-0.074673739,-0.7427068259999999,-2.2553291619999998,-0.011996355,-0.11373303400000001,-0.128881238,-0.02676797,-0.019737361000000002,-0.051327454,-0.034136396,-0.11521108099999999,-0.139787633,-1.345626019,-1.9623440280000002,-2.548314295,1.031408188,1.312043906,-9.88598922,-8.112584335,-11.98961287,-8.274796227000001,-9.547914917,-11.50503775,-7.348648676,-2.76525778,-8.689776420593262,-8.345194816589355,-9.12584400177002,-9.080409049987793,-10.391396522521973 -4280,4280,P249I,-0.066508207,0.020159114,-0.019073853999999998,-0.00871615,-1.8087900209999999,-0.007242304000000001,-0.01368472,-0.119331694,-0.070735332,0.055606207000000005,-0.01528798,0.005904561,-0.044052269000000005,0.003425446,-0.020857746,-1.549376663,-2.068203378,0.550480827,1.311128903,-8.599729611,-7.877147712999999,-10.51220399,-6.997642592999999,-8.336400856000001,-9.275252899,-7.07764273,-3.366366943,-7.848759174346924,-7.071978569030762,-7.782280445098877,-7.932529926300049,-8.79848575592041 -4281,4281,P249H,-0.011353552,0.001005746,0.005013401,-0.02053346,-1.15544864,-0.033206857,0.02855796,-0.051265064000000006,-0.010706568999999999,-0.005245001,0.007256492,-0.008658556999999999,0.018685358,-0.013801321,-0.027265598,-0.772215724,-1.538681556,0.5913726460000001,1.3656514709999998,-7.010845582999999,-7.110202537999999,-7.872221328999999,-5.8259726789999995,-6.868502296,-7.377329071,-6.71245531,-2.309731186,-8.3539457321167,-7.2801666259765625,-8.163471221923828,-8.150076866149902,-8.891382217407227 -4282,4282,P249K,-0.134751354,-0.014551571999999999,0.016346997,0.036101923,-0.073359069,-0.017275449,-0.043922322,-0.225580385,-0.025569388999999998,0.0070558159999999995,-0.036158959,0.043782627000000005,-0.011088633,0.059231362999999995,0.012972481999999999,0.064276775,-0.21099491199999998,1.109854876,2.9255198019999997,-5.924984605,-6.76766021,-6.354243256,-4.666414734,-5.688364967,-6.148239861,-6.2552095439999995,-3.582647438,-6.840160846710205,-5.627566337585449,-6.042462348937988,-6.135252475738525,-7.152623176574707 -4283,4283,P249M,-0.028820572000000003,-0.0011662060000000001,-0.033574828,0.006654939,-0.703567053,0.051505819,0.008838243,-0.066479386,0.048516501,0.024127421,-0.026459833,-0.030609044,-0.036540611,0.017160375,-0.003850497,-0.3246274,-1.082506706,1.4810637430000002,1.9712603969999998,-8.64603517,-7.877293823,-10.49444165,-7.813503798999999,-8.217487984,-8.827448593,-7.33628834,-2.562113283,-8.783870697021484,-7.890713691711426,-8.731589317321777,-8.815170288085938,-9.95238208770752 -4284,4284,P249L,0.002286881,-0.00450836,0.007697221,-0.019641353,-1.682206154,-0.010473551,0.0086805,-0.004106739,0.005328446999999999,-0.016382312,0.007365593,0.008445275,0.006949166999999999,0.008294585,-0.047577290999999994,-1.434248304,-1.930164004,0.590954057,1.317453745,-6.819934868,-5.786453125,-9.44943103,-6.202299728,-6.238078194,-6.423412262,-6.64894929,-0.572270815,-6.974076271057129,-6.156472682952881,-7.068447589874268,-7.439823150634766,-8.145136833190918 -4285,4285,P249N,-0.070778995,0.084193028,0.007902225,-0.003152983,-0.450898064,0.07924944099999999,-0.020784653,-0.120773337,-0.06731727,0.07862057,0.08976548599999999,-0.035063386,0.050867836,-0.034215786,0.02790982,-0.251435106,-0.650361022,1.6494694669999999,2.212074529,-5.911778421,-6.719954491,-5.962324936,-5.390713524,-5.300014824,-6.1858843310000005,-5.822224351,-3.3715376839999998,-8.561419486999512,-6.769409656524658,-8.264073371887207,-7.421605587005615,-8.37929916381836 -4286,4286,P249Q,-0.057459305999999995,0.009884568,0.019006563,-0.041142532,-0.292078371,-0.037630558,-0.037367095,-0.077551517,0.003048957,0.033240399,-0.013471263999999998,0.014359058999999999,0.023654067,-0.011596182,-0.070688881,-0.083055104,-0.501101637,1.530051592,2.527548925,-6.436507552,-6.8101110689999995,-7.2399050979999995,-5.321924835,-6.393886017000001,-6.416710739,-6.321260862000001,-4.110613224,-7.383126258850098,-6.273754119873047,-6.939553737640381,-6.85391902923584,-7.783924102783203 -4287,4287,P249S,-0.018875764,-0.000343416,-0.0325316,0.021475462999999997,-0.658121898,-0.001453281,-0.037468645,-0.00028288200000000003,0.002959615,0.028941658,-0.02962849,0.0033121509999999997,-0.068375351,0.050335828,-0.007384902,-0.334281628,-0.981962167,1.4625719209999999,1.9867951169999998,-3.423505547,-3.226883018,-3.5725658719999998,-3.2898855589999996,-3.878697212,-3.149496071,-5.057118043,-1.9872283480000001,-7.014645099639893,-6.106910705566406,-7.186975002288818,-6.642383098602295,-6.823214530944824 -4288,4288,P249R,0.001171349,0.02185184,-0.010215739,-0.000622254,-0.132884736,0.013331525,-0.0007789769999999999,0.003121674,0.040207357,0.02919626,0.014507418999999999,0.004762312,-0.025193788999999998,-0.000618172,-0.000626336,-0.05502056,-0.210748911,1.3296244590000001,2.548542363,-5.0715439380000005,-4.631601348999999,-6.766330246,-4.098231064,-5.247879601,-4.613677429,-4.777417654,-2.5315596869999997,-7.744614124298096,-6.26293420791626,-6.6996989250183105,-7.109372138977051,-7.8408732414245605 -4289,4289,P249T,-0.019143774,0.037485064,0.003564467,0.002096796,-0.890274021,0.025965723,-0.013009418,-0.02527813,0.009150563,0.060638644000000005,0.014331483,0.038105494,-0.030976561,0.005108385,-0.000914793,-0.48937873299999995,-1.291169309,0.7355418109999999,1.456197072,-3.722260025,-4.231165787,-3.5937457960000003,-3.060887047,-4.142802742,-3.5826987530000003,-4.935841054,-1.427950109,-7.559677600860596,-6.209860801696777,-7.149479866027832,-6.874080657958984,-7.478654861450195 -4290,4290,P249W,-0.008029177,-0.026755557000000003,-0.002592061,-1.089430358,-2.5984718940000002,-0.028480413,0.012012223999999998,-0.028070578,0.034429982000000005,-0.010061453,-0.043449660999999994,-0.030627777000000002,0.025443656000000002,-0.5055619929999999,-1.673298723,-2.402014038,-2.7949297489999996,1.447972918,1.2415384390000002,-9.832979605,-8.534593994,-11.72788525,-8.918576172,-10.34306238,-9.640780227999999,-7.190239254,-4.281599382,-10.499053955078125,-10.744494438171387,-10.945009231567383,-11.098442077636719,-12.333545684814453 -4291,4291,P249V,-0.005313748,-0.021505232000000003,-0.013830489,-0.002349045,-1.3480607409999998,-0.032854463,-0.009814656,-0.00081284,-0.000725701,-0.024327678999999998,-0.018682783999999997,-0.033692191,0.0060312130000000005,0.00556039,-0.010258479000000001,-1.184433628,-1.5116878530000002,0.8362853490000001,1.355854429,-6.779513597,-6.013790375,-8.38602243,-5.721291892999999,-6.619355682,-7.157107605,-6.185071484,-2.7509979469999997,-7.41303014755249,-6.693455696105957,-7.233091831207275,-7.6875457763671875,-8.302249908447266 -4292,4292,P249Y,0.010223564000000001,0.042372485999999994,-0.003694421,-0.351560821,-1.7162852180000001,0.018419991,0.087665351,-0.06721822400000001,0.02678229,0.01095086,0.073794112,-0.013439575,0.006050733000000001,-0.115991786,-0.587129855,-1.539066517,-1.8935039180000002,1.044873951,1.348934099,-9.792381857,-9.198796394,-12.15349696,-7.8002230379999995,-9.350214218,-10.45917867,-6.861348336,-1.9062949409999999,-9.372527122497559,-8.752245903015137,-9.727038383483887,-9.39475154876709,-10.938800811767578 -4293,4293,D250A,-0.034311400000000006,-0.056401672,-0.040072522,-0.045835838,0.018321109,-0.006250416999999999,-0.028305554,-0.040317245,-0.030596206,-0.076374213,-0.03642913,-0.080707907,0.000562864,-0.047468311,-0.044203365,0.004781946,0.031860272,1.228595653,2.552268184,-2.2588561780000003,-2.101019646,-2.4915460130000002,-2.8817450410000003,-2.150501579,-1.669468613,-2.495889857,0.23284168100000002,-4.461928367614746,-4.8860859870910645,-2.5674245357513428,-3.355900526046753,-2.793523073196411 -4294,4294,D250C,-0.046761057,-0.055349554,-0.100722086,-0.057974665,0.002043014,-0.035098594,-0.044452755999999996,-0.049069358,-0.038910045,-0.051152522,-0.059546586,-0.062710683,-0.13873348800000002,-0.036107089,-0.07984224,0.028185678999999998,-0.024099652000000003,1.140851641,2.701421792,-7.200121104,-7.309413925,-7.550586182000001,-7.374590607000001,-7.196072403,-6.569942406,-7.709528849,-7.373319994,-9.634780883789062,-9.585495948791504,-9.60972785949707,-9.414241790771484,-9.825014114379883 -4295,4295,D250E,-0.053075005999999994,-0.055272993,-0.080058388,-0.052378938,-0.040105619,-0.016392834,-0.040161527,-0.065988485,0.006548986999999999,-0.082088534,-0.028457451,-0.13712169800000001,-0.022995077000000003,-0.024191754,-0.08056612099999999,0.007461276,-0.08767251300000001,1.258682364,2.591044681,-0.997211057,-1.201031754,-0.805085663,-1.3681439819999999,-1.135382149,-0.47641173600000003,-2.666249654,0.162554283,-3.5555124282836914,-4.761992454528809,-2.863508701324463,-3.3834986686706543,-2.944659948348999 -4296,4296,D250G,-0.035801638,-0.053691910999999995,-0.052782130999999996,-0.059139107999999996,-0.01997566,-0.014804711000000002,-0.041515416,-0.03008786,-0.012805356,-0.078792552,-0.02859127,-0.102018791,-0.00354547,-0.070084187,-0.048194029000000006,-0.024559005,-0.015392313999999999,1.543610422,3.106887046,-2.411519276,-1.7443245319999998,-3.139050262,-2.9849700930000003,-2.325815887,-1.863435608,-2.3048281569999998,-0.335101319,-4.951992511749268,-5.510455131530762,-4.853554725646973,-5.124375820159912,-4.753252983093262 -4297,4297,D250F,-0.030430468,-0.056233375999999995,-0.036455503,-0.062189592,0.00293398,-0.072130489,-0.026584695,-0.034276241,-0.056147805999999995,-0.07937825,-0.033088502,-0.064401094,-0.008509911,-0.03718057,-0.08719861300000001,-0.013438855,0.019306814,1.186638969,2.423267269,-6.130720723,-6.38076899,-6.464759575,-6.104689919,-5.954971481,-5.748413651,-6.634354269,-4.487608928,-7.418631076812744,-8.311402320861816,-6.938066482543945,-7.857928276062012,-7.510595321655273 -4298,4298,D250I,-0.04399044,-0.093715849,-0.036430528999999996,-0.086022363,-0.144254011,-0.064806034,-0.055075545,-0.032905335,-0.073155617,-0.102504675,-0.084927023,-0.083249875,0.010388818000000001,-0.062241495,-0.109803231,-0.11937089,-0.16913713100000002,1.396988942,2.265181592,-5.873930118,-5.938421783,-6.307766602,-5.9500929110000005,-5.9743108220000005,-5.199058472,-5.419596599999999,-3.6867524360000004,-6.281520366668701,-7.232340335845947,-4.839682102203369,-6.631203651428223,-5.426389217376709 -4299,4299,D250H,-0.043928928,-0.047977226,-0.059884152,-0.04110273,-0.008857985,-0.012362725,-0.041156733,-0.046701122000000005,0.019993328,-0.103251839,0.007297388,-0.087065078,-0.032703225,-0.046636421,-0.035569038,-0.049668914,0.031952944,1.3560064680000001,2.430711902,-3.869732083,-4.0129155039999995,-3.81170166,-4.063011505,-4.044136673,-3.416895073,-4.741006504,-2.251801038,-5.955653667449951,-6.506993770599365,-5.193419456481934,-6.3511834144592285,-5.159140586853027 -4300,4300,D250K,-0.095810235,-0.11364980699999999,-0.100958588,-0.14032686800000002,-0.064669503,-0.034820627,-0.123669993,-0.067950476,-0.060054723,-0.194275048,-0.033024566,-0.104793845,-0.09712333,-0.09466486699999999,-0.18598886899999997,-0.000765407,-0.128573598,1.412929624,2.559652055,-1.554830315,-2.1369685819999997,-2.019162819,-1.721846512,-0.971579193,-0.924594467,-2.346451509,0.143344869,-4.100347995758057,-5.455179214477539,-2.809006929397583,-4.400538921356201,-2.3270721435546875 -4301,4301,D250M,-0.038329995,-0.09813788300000001,-0.053397892999999995,-0.065352192,-0.003194611,-0.020398395,-0.029460264,-0.047199726,-0.074607795,-0.09332350699999999,-0.102952258,-0.055534945999999995,-0.05126084,-0.056578924,-0.074125459,0.020153261999999998,-0.026542483999999998,1.076833718,2.62284945,-5.959386055,-5.325632973,-6.393387947000001,-6.637708542,-5.74915921,-5.6910416029999995,-5.443172873,-3.5922466060000002,-7.230806350708008,-7.963191986083984,-6.197028636932373,-7.454434394836426,-6.474737644195557 -4302,4302,D250L,-0.020903816000000002,-0.058963735999999996,-0.057688328,-0.072366492,-0.036004745,-0.034402029,-0.02540605,-0.016401581000000002,-0.013702978000000001,-0.105613377,-0.012314094,-0.104887132,-0.010489523,-0.070130152,-0.07460283200000001,-0.049979160999999994,-0.022030328999999998,1.259084239,2.364667216,-4.979605833,-4.731705032,-5.096466400000001,-5.950430602999999,-4.724300223999999,-4.395126907,-4.476080855,-2.459712917,-5.663358211517334,-7.010565757751465,-4.867613315582275,-6.22066593170166,-5.27494478225708 -4303,4303,D250N,-0.049927976,-0.083286,-0.044760057,-0.062807818,0.052589912,-0.054596294000000004,-0.061133427000000004,-0.038722525,0.006235116,-0.085180934,-0.081391065,-0.087821031,-0.0016990820000000002,-0.056347216,-0.06926842,0.048826363,0.056353460999999994,1.320658561,2.821707424,-2.3017509919999997,-2.549996925,-2.511057091,-1.920041374,-2.30113102,-2.226528549,-2.991975188,-1.109003476,-4.336603164672852,-4.042062759399414,-3.953195810317993,-4.292494773864746,-3.932102918624878 -4304,4304,D250Q,-0.035824378999999996,-0.089563318,-0.047413536,-0.046942938,0.040564806,-0.054382627,-0.057979822,-0.013668936000000001,-0.129113894,-0.104784688,-0.074341947,-0.09558789300000001,0.000760822,-0.065266193,-0.028619682,0.004420312,0.07670930000000001,1.27782736,2.666259648,-3.513322182,-3.30660878,-3.788338638,-4.176928139,-3.585806976,-2.708928375,-3.960110887,-0.8835785190000001,-4.304211616516113,-5.1496686935424805,-3.2570626735687256,-4.476193428039551,-3.659839391708374 -4305,4305,D250P,-0.02270569,-0.08359243200000001,-0.068639353,-0.061241505,-0.440746278,-0.00737404,-0.00010174299999999999,-0.045309637,-0.039762905,-0.103838301,-0.063346562,-0.080796998,-0.056481708,-0.050645237,-0.07183777200000001,-0.233316976,-0.648175579,1.4293193130000001,2.053585997,-1.7311053730000001,-0.114875885,-1.185726288,-4.120892754,-2.236009415,-0.9980225220000001,-2.230483065,2.637484111,-4.854586601257324,-6.73951530456543,-2.4005374908447266,-0.9023914337158203,-1.0381555557250977 -4306,4306,D250S,0.008853191,-0.043927192999999996,-0.04027554,-0.024828407,0.024758952999999997,-0.041445044,0.014548573,0.003157809,-0.05077589,-0.08951853900000001,0.001664154,-0.104771805,0.024220725,-0.038869789,-0.010787024,0.006534995,0.042982911,1.270488892,2.533330658,-2.582229079,-2.650827744,-2.349997009,-2.7590873030000003,-3.32093,-1.830303337,-3.2537595319999997,-0.623608091,-4.665090560913086,-5.241954803466797,-3.723189115524292,-4.371499061584473,-3.9665558338165283 -4307,4307,D250R,-0.015164748,-0.03008887,-0.036792443,-0.04641496,0.024388551,0.002411685,-0.024712458,-0.005617036999999999,-0.017739086,-0.06966974299999999,0.009492003,-0.085302153,0.011717267,-0.051472339000000006,-0.041357581000000004,-0.00838789,0.057164991,1.367983386,2.598846434,-3.6985957860000003,-4.152090775,-3.6606879039999995,-4.454886467,-3.768724358,-2.456589424,-3.630464412,-1.03244067,-6.075926780700684,-7.202932357788086,-4.530549049377441,-6.424980163574219,-4.613391399383545 -4308,4308,D250T,-0.029527937,-0.058690775,-0.035571633,-0.062475662,-0.051200364000000005,0.013103855,-0.041828111,-0.017227763,-0.040009707,-0.10726846400000001,-0.010113085,-0.082266195,0.011122928999999998,-0.089185316,-0.035766007999999995,-0.028519137000000003,-0.073881591,1.2166231140000001,2.35890501,-2.636740903,-2.550002594,-3.203403137,-2.831852928,-2.603488106,-1.994957748,-3.1020382389999996,-0.721311226,-4.87495756149292,-5.773420810699463,-4.340808868408203,-5.101370334625244,-4.361240386962891 -4309,4309,D250W,-0.026401358,-0.06099029,-0.075976582,-0.077202904,-0.04440584,-0.078541343,-0.040920547,-0.011882169,-0.067649198,-0.094923735,-0.027056844,-0.13170417,-0.020248993,-0.068802606,-0.08560320199999999,-0.037807439,-0.051004241,1.323961605,2.40757037,-7.291233484,-7.460956413,-7.231095207,-7.764191444,-7.132293762000001,-6.867630592,-7.709528849,-7.373319994,-9.132905006408691,-10.972025871276855,-9.160469055175781,-9.855764389038086,-8.947931289672852 -4310,4310,D250V,-0.015911789,-0.032001896,-0.028484045,-0.017952408,-0.065919361,-0.043230027000000004,-0.014436939,-0.017386638,-0.054077944,-0.054151780999999996,-0.00985201,-0.067174119,0.01020603,-0.004999677,-0.030905138999999998,-0.045879215,-0.08595950699999999,1.282303215,2.399132985,-4.452135561,-4.236476799,-5.03330896,-4.692470169,-4.531948303,-3.7664735719999998,-4.316704121,-2.130332556,-5.649245738983154,-6.5131354331970215,-3.868464231491089,-5.476284027099609,-4.352086544036865 -4311,4311,D250Y,-0.045159649,-0.06488633099999999,-0.088249186,-0.050873627000000005,-0.045429450999999996,-0.004258543,-0.012424768999999999,-0.077894528,0.04466585,-0.09181151300000001,-0.037961149,-0.09854489599999999,-0.077953476,-0.091981992,-0.009765262,-0.044595322,-0.04626358,1.3634295769999998,2.39221161,-5.599197983,-6.083595322000001,-5.67045137,-5.221831078,-5.709211487,-5.310900658,-5.351538542,-4.395535105,-7.395782470703125,-8.502023696899414,-6.9019575119018555,-7.937894821166992,-7.182021617889404 -4312,4312,G251A,-0.019234852,0.003103572,-0.0029835720000000003,-0.00410856,-0.06441906,0.000396871,-0.033724718,-0.004744985,-0.0032196409999999996,0.005975378000000001,0.00023176599999999998,0.026616266,-0.032583409,-0.002673687,-0.005543433,-0.047772782,-0.081065337,1.325552123,2.394828569,-2.538602922,-3.316718178,-2.1711925130000003,-1.413539871,-3.356177628,-2.435386421,-4.0974474999999995,-1.501870431,-4.366922855377197,-5.534334182739258,-5.322395324707031,-5.668585777282715,-5.207643508911133 -4313,4313,G251C,0.01353473,-0.002471768,-0.013907428000000001,-0.039658242,-0.462420625,-0.078066599,0.025774156,0.001295303,0.026346893,0.019174262,-0.024117798,-0.004997194,-0.022817662000000002,-0.012441082,-0.066875401,-0.22032860199999998,-0.704512648,1.4214866780000002,2.1103286619999997,-6.692753555,-7.1063160860000005,-7.138986557000001,-5.83233989,-7.039526688,-6.346598557,-7.649084211,-4.927063355,-9.05650520324707,-9.433250427246094,-10.176755905151367,-9.980175971984863,-12.120674133300781 -4314,4314,G251E,-0.121813674,-0.004683363,-0.068405993,-0.041845212,-0.086343213,0.006829671,-0.098050353,-0.14557699400000002,0.033839921,0.108432399,-0.117799124,0.030235182000000003,-0.167047167,0.076879796,-0.16057022,0.010370705,-0.183057131,1.318668048,2.949930464,-2.163243079,-2.90920723,-2.026477455,-1.164674553,-2.51436274,-2.201493416,-3.932642665,-1.42032058,-4.143054008483887,-6.808760166168213,-5.242039203643799,-6.153766632080078,-5.135029315948486 -4315,4315,G251D,-0.08724859900000001,-0.018709866999999998,-0.028835936,-0.036620185,-0.083212315,0.047037409,-0.086332122,-0.088165076,-0.005342829,0.022112777000000004,-0.059532510999999996,-0.01004389,-0.047627982,-0.006384882,-0.066855487,-0.044178484000000004,-0.122246145,1.2672870109999999,2.4455499990000003,-2.23468378,-3.018454727,-1.6713876269999999,-1.257369331,-2.804944008,-2.421263206,-3.264829464,0.348731711,-4.11439323425293,-5.979249000549316,-4.526668071746826,-5.376275062561035,-4.518526077270508 -4316,4316,G251F,-0.009961013000000001,0.038854633,-0.08159229400000001,0.012606683999999998,-0.36401895,-0.003059031,-0.033889672999999995,0.013967647,0.010837649,0.034518812,0.043190454,-0.044151425999999994,-0.119033162,-0.016512144,0.041725512,-0.235960883,-0.492077017,1.390903398,2.0469748819999998,-7.387342218,-7.010693412999999,-8.824362198,-6.647225601000001,-7.58615554,-6.868274337999999,-7.759209956,-5.077593166000001,-7.647891998291016,-9.205694198608398,-9.09670352935791,-9.433248519897461,-9.924367904663086 -4317,4317,G251I,-0.008367595,0.047990435,0.005569009000000001,0.005130771,-1.282882225,0.00238011,-0.027761927999999998,0.011026738999999999,0.03025069,0.064485355,0.031495514,0.071406627,-0.060268609,-0.036850719,0.047112260999999996,-0.5867844329999999,-1.978980016,0.935186815,1.496450525,-7.182386806,-7.401642798999999,-8.199230522,-5.992268494,-7.523895676,-6.794896538,-8.115556632999999,-5.625162735,-7.36088752746582,-8.680437088012695,-8.242746353149414,-8.854475975036621,-9.155405044555664 -4318,4318,G251H,-0.049572215999999995,0.0073088580000000005,-0.063748776,0.008159742,-0.07890309400000001,0.006517490999999999,-0.079185559,-0.019958873000000002,-0.030334067000000003,0.0061915419999999995,0.008426173,-0.005831025,-0.121666526,0.019969745,-0.0036502609999999997,-0.039841724,-0.117964464,1.192226489,2.404097592,-3.869022186,-4.491677719,-4.26505883,-3.320923943,-4.098956749,-3.16849369,-3.953649888,-1.702497528,-5.792541027069092,-7.384028434753418,-6.447329044342041,-7.6595377922058105,-7.25611686706543 -4319,4319,G251K,0.047224199999999994,0.12057648800000001,0.030751837999999997,0.091126554,0.085538885,-0.09537708199999999,0.037755677,0.056692722,0.0045887,0.197122081,0.044030895,0.043114615,0.01838906,0.127780917,0.054472190999999996,0.030022623999999998,0.141055145,1.215730156,2.850969187,-2.511589021,-3.02040847,-2.835493446,-2.1333002619999997,-2.522695129,-2.046047798,-3.5258635760000003,-1.243172285,-5.008428573608398,-5.798494815826416,-5.54592227935791,-6.655465602874756,-5.449799537658691 -4320,4320,G251M,0.022353993,0.097226344,0.09824291800000001,0.018273782,0.008838474,-0.03178757,-0.021560376000000003,0.066268361,0.074631652,0.004899665,0.18955302300000001,0.052015568,0.144470268,0.011468988000000001,0.025078575,-0.033029122,0.050706069000000006,1.232195707,2.4882579280000003,-7.652187949,-8.070173019,-8.9757407,-6.591430511,-7.923417809,-6.700177704,-8.611842622000001,-6.49544252,-7.52273416519165,-8.584750175476074,-8.395051956176758,-9.314805030822754,-9.149686813354492 -4321,4321,G251L,-0.06416598,-0.022257133999999998,-0.006624024,-0.01349598,-0.19331511899999998,0.001130294,-0.07295287,-0.05537909,-0.012356543999999999,0.023954773999999998,-0.06846904200000001,0.034874203,-0.048122251,0.010958986,-0.037950946,-0.10254363699999999,-0.2840866,1.3641896409999998,2.335292185,-6.655771392999999,-6.959609672999999,-8.30505619,-5.388981193999999,-6.802414612000001,-5.822795296000001,-6.9825797220000005,-4.926629617,-5.765098571777344,-7.759860038757324,-7.187234878540039,-8.117929458618164,-8.52003002166748 -4322,4322,G251N,0.004120294,-0.006098065,0.011532243000000001,-0.041052975,-0.08669194,-0.048788584,0.00564745,0.002593137,-0.08825393599999999,-0.014380384,0.002184255,0.074152439,-0.051087954000000005,-0.035299666,-0.046806284000000004,-0.038108647,-0.135275232,1.443911584,2.5943434180000002,-2.429296396,-3.190290909,-2.6994366989999996,-1.985289871,-1.772748161,-2.498716339,-3.568728107,-0.22108968199999998,-4.829436302185059,-5.332699775695801,-4.783462047576904,-5.8397216796875,-4.876696586608887 -4323,4323,G251Q,-0.002671093,-0.03194097,-0.029632515,-0.033220992000000005,-0.058285538,-0.035206741,-0.022279764,0.016937578000000002,0.069681198,0.024710522000000002,-0.088592461,-0.026835107,-0.032429923,-0.050566422,-0.015875562,-0.075548382,-0.041022694,1.491438144,2.518791003,-2.542327025,-3.420798645,-3.013189301,-1.6655121380000002,-2.426090904,-2.186044136,-3.8824726939999996,-1.8083557630000002,-4.610179424285889,-6.635716915130615,-5.465310096740723,-6.846202373504639,-6.025355339050293 -4324,4324,G251P,-0.020497067,-0.008055659,-0.037718312999999996,-0.019530329,-0.608712558,-0.016795271,-0.032068875,-0.008925259,-0.0008516089999999999,0.014636895,-0.030748212999999996,0.0075471309999999995,-0.08298375599999999,-0.0034018890000000004,-0.035658768,-0.293127036,-0.92429808,1.498034246,2.0529496419999997,-4.084390462,-5.018932632,-4.858112,-3.064411942,-5.0637789689999995,-2.416716766,-4.513094894,-3.0628773760000003,-5.127634525299072,-8.014405250549316,-7.0010905265808105,-6.418078422546387,-6.894096374511719 -4325,4325,G251S,-0.06350524,0.001434205,-0.023076917000000002,-0.033503494,-0.065623646,-0.0021181760000000003,-0.06695010000000001,-0.060060379000000004,0.011365346,0.046157677,-0.043289268,0.026316666000000002,-0.07247050000000001,0.029465744,-0.09647273099999999,-0.014155504,-0.11709178699999999,1.169552822,2.52275185,-2.865686665,-3.3505922389999996,-2.986963921,-1.9370643230000002,-3.365802307,-2.688010536,-3.487509062,-1.097718043,-4.709704399108887,-6.156099319458008,-5.518008232116699,-6.090177536010742,-5.64902400970459 -4326,4326,G251R,-0.002208394,0.0036009059999999996,0.006220392,-0.021013165,-0.056149079000000005,-0.026139448,-0.006939086,0.002522298,0.017270808999999998,0.020344763000000002,-0.013142952,0.028768064,-0.01632728,-0.001884425,-0.040141905,-0.029064659,-0.083233499,1.1811270440000001,2.4637254580000003,-4.146481209,-5.351184555,-4.634647514,-3.175568527,-4.627047325,-2.9439581219999997,-5.408371067000001,-2.126816248,-5.347352504730225,-6.352804183959961,-6.204851150512695,-7.271296977996826,-6.895056247711182 -4327,4327,G251T,-0.01194882,-0.026391987000000002,-0.038451097000000004,-0.023488552000000003,-0.214043801,-0.05659572400000001,-0.016771423,-0.007126217,0.02670127,-0.031682293,-0.02110168,-0.0006612489999999999,-0.076240945,0.011277105,-0.058254207999999995,-0.123457007,-0.304630595,1.360970451,2.2805769259999997,-3.5443283539999997,-4.1140202939999995,-4.012932922,-2.751586357,-3.607063171,-3.2360390239999997,-4.966095978,-1.983958631,-5.242430210113525,-6.93722677230835,-6.062304496765137,-6.819456577301025,-6.341390132904053 -4328,4328,G251W,-0.078074531,-0.028646297999999997,-0.046584939000000006,-0.032309998,-0.899293474,-0.014130346,-0.075245427,-0.080903634,-0.035382045,0.009849495,-0.067142091,-0.001120505,-0.09204937199999999,-0.013268751,-0.051351244000000004,-0.575320908,-1.223266039,0.8051561290000001,1.449951859,-7.169713205,-7.278478889,-8.54142205,-6.292318099999999,-7.42912513,-6.307221855,-7.879695301,-5.297417607,-8.808127403259277,-10.986896514892578,-10.410314559936523,-10.745277404785156,-11.26870346069336 -4329,4329,G251V,-0.062207818,0.00608112,-0.019932421000000002,-0.008840862,-0.8962735140000001,-0.05705845,-0.069197275,-0.05521836,0.010306275,0.042694362,-0.030532122999999998,0.036777771,-0.076642613,0.038065784,-0.055747507,-0.538965154,-1.253581874,0.60238637,1.406347819,-5.451162943,-6.0612441939999995,-6.135545471,-4.29610775,-5.8805138470000005,-4.88240345,-6.7492255860000006,-3.8998776910000004,-6.543011665344238,-7.990179061889648,-7.218771457672119,-7.954190731048584,-8.215182304382324 -4330,4330,G251Y,0.059122007000000004,-0.016266408,-0.023295325,-0.024735992999999998,-0.181934202,0.035754201,0.084197245,0.034046768,-0.034081435,-0.088482105,0.05594929,-0.025503386,-0.021087263999999998,-0.08540111,0.035929124,-0.182040717,-0.181827687,1.4583066359999999,2.15946925,-6.648239113,-6.484736786,-7.739146469,-6.16349472,-6.951373337000001,-5.9024442520000004,-7.146648611,-3.453854573,-7.759561538696289,-9.192678451538086,-8.604991912841797,-9.423707962036133,-9.503461837768555 -4331,4331,K252A,-0.063298778,-0.048230377000000005,-0.032751352000000004,-0.031522141000000004,-0.016785141,-0.009214043,-0.07122915099999999,-0.055368404,-0.007681429,-0.004421418,-0.092039336,0.002008809,-0.067511513,0.019317973999999998,-0.082362256,-0.028756043,-0.004814238,1.0988536770000001,2.35255746,-2.944894249,-2.2512293469999998,-2.957151474,-3.2026588360000003,-3.141654511,-3.171777077,-4.032847647,-0.345653435,-3.869832754135132,-5.451187610626221,-5.9388580322265625,-4.464264869689941,-5.785959243774414 -4332,4332,K252C,-0.075002662,-0.07209631400000001,-0.068099874,-0.08381664900000001,-0.082285745,-0.062845745,-0.059073358,-0.090931965,-0.060138211,-0.00672643,-0.13746619699999998,-0.008860906,-0.12733884199999998,-0.013121677,-0.15451162,-0.038310904,-0.126260586,1.311443082,2.507118904,-5.424117925,-5.117850403,-4.974972878,-5.585395836,-6.435259682000001,-5.007110825,-5.552981748,-1.835993024,-8.556808471679688,-8.456579208374023,-9.87677001953125,-8.570439338684082,-11.09206485748291 -4333,4333,K252E,-0.07352229099999999,-0.041302239,-0.033745383,-0.063028645,-0.006253246,-0.018833847,-0.06432579,-0.082718792,0.007874446,0.030374847000000003,-0.112979324,-0.009322283,-0.058168482,-0.012384757,-0.11367253199999999,-0.041920026,0.029413535,1.337439289,2.544722429,-2.7219291689999996,-1.923816208,-2.116819099,-3.233305595,-3.91396402,-2.421740921,-3.833381183,-0.345725204,-4.386499404907227,-6.364161968231201,-6.78104305267334,-6.153158187866211,-6.587991714477539 -4334,4334,K252D,0.051397687000000004,0.07362913900000001,0.113703883,0.070681037,-0.032738769,-0.012087153,0.096671492,0.006123880999999999,-0.071512054,0.196580647,-0.04932237,0.186757736,0.04065003,0.17748770600000002,-0.036125633,0.051674257,-0.117151795,1.027191307,2.886890522,-2.834574042,-2.269511276,-2.247516113,-4.349159828,-4.416551949,-0.890131042,-3.4479694139999997,-0.945135176,-5.111667156219482,-7.9971022605896,-8.061979293823242,-6.770117282867432,-8.166279792785645 -4335,4335,K252G,-0.08016205700000001,-0.050035275,-0.036644239,-0.04523371599999999,-0.029883316,-0.0037803040000000004,-0.088717352,-0.07160676099999999,0.012332271,0.0026401659999999998,-0.102710716,-0.009650885,-0.063637592,-0.008171017,-0.082296415,-0.055640817,-0.004125814,1.334159116,2.451291407,-1.962827184,-1.1574125370000001,-1.359059143,-3.0199984360000003,-2.491211426,-1.786454376,-3.444826763,2.362656339,-4.830127716064453,-7.249121189117432,-6.852113723754883,-4.5054755210876465,-7.135815143585205 -4336,4336,K252F,-0.19298726800000002,-0.029184536,-0.082006255,-0.038731126,-0.051141275,-0.114200371,-0.194048113,-0.19192642199999999,-0.078563521,0.132000591,-0.190369663,0.050175019,-0.214187529,0.19188552600000003,-0.269347777,-0.038663273,-0.063619277,1.217639234,2.643709807,-8.378540112,-7.450734695,-8.202617546,-9.628371346,-8.691528801,-7.919448173999999,-7.9398554379999995,-5.726879704,-7.678124904632568,-7.675099849700928,-9.268641471862793,-8.066854476928711,-9.387510299682617 -4337,4337,K252I,-0.010280645,0.002251754,-0.040306875,-0.026807661,-0.06945950599999999,-0.079984477,-0.040325056,0.019763766000000002,0.0032995259999999997,0.028251154,-0.023747646,0.019228115,-0.099841865,0.028550399,-0.08216572,0.006166936,-0.14508594800000002,1.1575645479999999,2.598516951,-6.229108476,-5.708719727,-5.309199509,-7.59294326,-6.050250626,-6.48442926,-6.346698814,-3.0783234239999997,-6.587375640869141,-6.646982192993164,-7.627573013305664,-7.540818214416504,-8.287644386291504 -4338,4338,K252H,-0.02318934,-0.058681820999999995,-0.07468414599999999,-0.054277842,0.020027393,0.036079591,-0.01189539,-0.03448329,-0.005123261,-0.002453154,-0.114910488,-0.07054785400000001,-0.07882043700000001,-0.052929339000000006,-0.055626345,-0.09113528900000001,0.131190075,1.336667236,2.274121794,-2.959212085,-2.765050369,-3.105084679,-2.849462753,-3.474072739,-2.602389885,-3.979316222,-0.7014010359999999,-4.767460823059082,-5.801162242889404,-6.279162883758545,-5.152934551239014,-5.342231750488281 -4339,4339,K252M,-0.043674400999999995,-0.05764853599999999,-0.037585663,-0.020524079,0.003141287,-0.04663703,-0.036490616000000003,-0.050858185,0.015244958000000001,0.063643129,-0.17894020100000002,0.017916173,-0.093087499,-0.012234456000000001,-0.028813702000000004,-0.009843781,0.016126354,1.258926425,2.5311477940000002,-6.317925389,-5.839417221000001,-6.1213980260000005,-7.463211555,-6.260962105,-5.904638039,-6.289372717999999,-3.4078505789999998,-6.750804424285889,-6.802806854248047,-8.14466667175293,-7.199682235717773,-7.676782608032227 -4340,4340,K252L,-0.077578773,-0.043162704,-0.005602598,-0.016085631,-0.011493641,0.017671165,-0.073364912,-0.081792633,0.005518674,0.074210033,-0.16053544,0.067890514,-0.07909571,0.084320886,-0.116492148,0.025785876,-0.048773158,1.114435354,2.8029253169999997,-6.305521643,-5.901751633,-6.016930771,-7.50034388,-5.982432617000001,-6.126149315,-6.095260801,-3.07599693,-5.736902236938477,-5.854801654815674,-6.979915142059326,-6.156348705291748,-7.581715106964111 -4341,4341,K252N,-0.096134336,-0.023277807999999997,0.004524684,0.027575053,-0.051558232999999995,0.001423884,-0.065717569,-0.126551103,-0.036434899,0.06557547700000001,-0.112131093,0.136341514,-0.127292146,0.11686024,-0.06171013400000001,-0.008953209,-0.094163256,1.177658364,2.682016338,-2.154297289,-2.074240913,-1.4452569730000002,-2.951576012,-2.832109482,-1.468303062,-2.95487503,-0.737818194,-4.156148910522461,-6.157164573669434,-6.522008895874023,-5.0147294998168945,-6.390544414520264 -4342,4342,K252Q,-0.068663753,-0.08995771699999999,-0.097607995,-0.078815361,-0.035846092,0.031634367999999996,-0.049666672,-0.08766083300000001,-0.062239695,-0.038501102999999995,-0.141414331,-0.05938169099999999,-0.135834299,-0.057058983,-0.10057173900000001,-0.04643767,-0.025254513,1.3523852840000001,2.410872775,-2.383747905,-1.870189278,-2.456371506,-2.249125092,-3.119037865,-2.224015785,-3.1769522869999998,-0.754621653,-3.9716179370880127,-4.794882774353027,-5.056699752807617,-4.454862594604492,-4.946051597595215 -4343,4343,K252P,-0.096829419,-0.072766089,-0.054801683,-0.145968315,-1.765691743,0.044738309000000004,-0.10210816,-0.09155067800000001,-0.006512431,0.00592362,-0.151455798,-0.011460146000000001,-0.098143219,-0.002572565,-0.289364065,-1.561807075,-1.96957641,1.0129924909999999,1.342879475,-4.464865636,-3.7992673569999997,-2.909483688,-6.71058606,-4.633765144,-4.271225929,-5.267360429,-2.098047005,-6.410078048706055,-8.711563110351562,-7.078503608703613,-6.282447814941406,-9.404779434204102 -4344,4344,K252S,-0.047883199,-0.072090165,-0.020917138000000002,-0.033060477000000005,-0.00796242,0.004368757,-0.036084396,-0.059682001,0.013001581000000002,-0.0054428540000000004,-0.138737476,-0.004452895,-0.037381381,0.008085577,-0.07420653,-0.058529081,0.042604242,1.197783426,2.32353848,-2.9359374469999997,-3.0314363560000004,-2.669802269,-3.1700415189999998,-3.093028313,-2.7153787769999997,-3.167373335,-0.7547825640000001,-3.9812400341033936,-5.834609031677246,-6.3562235832214355,-3.9654018878936768,-6.123136520385742 -4345,4345,K252R,-0.070875587,-0.064565955,-0.053508451,-0.051573274,-0.008504702,0.019017309,-0.072373248,-0.06937792599999999,0.00689685,-0.007440197,-0.121691713,-0.02298216,-0.084034742,-0.018582856000000002,-0.084563692,-0.04708421,0.030074806000000003,1.347542398,2.499341491,-1.2713427990000001,-0.6479580229999999,-1.613501404,-0.9302994840000001,-1.823906342,-1.341048744,-2.457670217,1.415680518,-4.2933268547058105,-4.190052032470703,-3.694240093231201,-4.257505893707275,-4.49868106842041 -4346,4346,K252T,-0.06960172099999999,-0.06284770099999999,-0.032908196,-0.055363587,0.019358697,-0.009995595999999999,-0.059485851,-0.07971759099999999,0.001539934,0.01734889,-0.143044291,-0.011957041000000002,-0.05385935099999999,-0.010835761000000001,-0.09989141300000001,-0.014863896000000001,0.05358129,1.220668345,2.652885092,-3.244180469,-2.8341237180000003,-3.1456022110000004,-4.0503362119999995,-3.014693718,-3.1761464839999998,-3.247074635,-1.455989936,-4.223848342895508,-5.289381980895996,-6.147314071655273,-4.70973014831543,-6.112678050994873 -4347,4347,K252W,-0.107674551,-0.06465397099999999,-0.059512594,-0.061418439000000005,-0.190188435,0.034723095,-0.105197938,-0.11015116300000001,0.023601386000000002,-0.00599669,-0.123311251,-0.028014549,-0.091010638,-0.045592352,-0.077244525,-0.138047905,-0.24232896399999998,1.414912983,2.238588498,-7.84637086,-6.993026436,-7.351992615,-8.93636734,-8.298633087,-7.651834824,-7.677859637999999,-5.113839542,-9.88481330871582,-9.497293472290039,-10.492547988891602,-9.220718383789062,-10.481620788574219 -4348,4348,K252V,-0.075899315,-0.060956225,-0.042987587,-0.054090333,0.018514735,-0.008826168,-0.082168612,-0.069630018,0.020889991,0.004536879000000001,-0.126449328,0.013636748999999998,-0.099611923,0.008774973,-0.116955639,-0.04098686,0.07801632900000001,1.398183217,2.6027034540000002,-5.3836136020000005,-5.145466751,-4.436731285,-6.4451893689999995,-5.557301047999999,-5.333379555,-5.539175936,-2.4971958340000002,-5.620197296142578,-6.093656539916992,-6.782323837280273,-6.384377479553223,-7.116341590881348 -4349,4349,K252Y,-0.045335188,-0.02176642,-0.08520125099999999,-0.034060032999999997,-0.124149615,-0.08301449,-0.061634244000000005,-0.029036132000000003,0.013439158,0.06557547700000001,-0.109108316,-0.058184108,-0.112218394,0.032184683,-0.10030474800000001,-0.086450181,-0.161849049,1.324863951,2.368413399,-7.621254179,-6.864759003,-7.593892982000001,-8.503105026,-8.303756218,-6.840757667999999,-6.9356067029999995,-4.459813766,-7.108739376068115,-7.338773727416992,-8.962631225585938,-7.7574872970581055,-8.571231842041016 -4350,4350,P253A,0.012251763,0.004046874000000001,-0.049954887999999996,0.001008075,0.0060981130000000005,0.002563305,0.034396251,-0.009892726,0.019048765,-0.017053484,0.025147232000000002,-0.072545068,-0.027364707999999998,-0.055627577000000004,0.057643727,-0.019307713,0.031503939,1.393583924,2.645540692,-1.183180008,-1.753635544,-1.0685898440000001,-0.862322868,-1.391853096,-0.8394986879999999,-2.421316115,1.412387083,-4.388506889343262,-2.5605885982513428,-3.4086408615112305,-3.6691184043884277,-4.802111625671387 -4351,4351,P253C,0.055546012,-0.028338737000000003,-0.061890195999999995,0.042706590999999995,-0.305743969,-0.0053568719999999995,0.08034095200000001,0.030751071,-0.06589953,-0.062646809,0.005969335,-0.08943488,-0.034345512,-0.034744383,0.12015756400000001,-0.239671408,-0.37181653,1.478797805,2.087389375,-7.162550005,-7.383469894,-5.414369301,-7.919471489,-8.548474197,-6.546965141,-8.277241158999999,-4.32613577,-9.394952774047852,-7.51089334487915,-9.187230110168457,-10.773215293884277,-11.892807006835938 -4352,4352,P253E,0.010219978000000001,-0.035728552999999996,-0.043534252,-0.011474643,-0.7171818609999999,0.007644061,0.02985852,-0.009418565,-0.034446622999999996,-0.09293145800000001,0.021474352000000002,-0.071949533,-0.015118971,-0.062274777,0.039325491000000004,-0.493145382,-0.94121834,1.5034402480000002,1.8385867580000002,-3.265970053,-3.9491202010000004,-1.541419968,-4.053112984,-3.7565001369999997,-3.0296969760000003,-3.975587286,0.23453589100000002,-5.214040756225586,-5.21010684967041,-5.93159294128418,-7.000130653381348,-6.53609561920166 -4353,4353,P253D,0.059739638,-0.011943905,0.023833925,0.075834973,-0.716142335,-0.053063988,0.07013533799999999,0.049343937000000004,-0.053861482,-0.028021399,0.004133589,0.019902153,0.027765696,0.044654837,0.10701510800000001,-0.423199334,-1.009085335,0.8306945370000001,1.5197217809999999,-4.064997838,-4.3147150960000005,-2.632504944,-4.784869652,-4.45723037,-4.135669128,-4.922685774,0.587284226,-5.108117580413818,-5.254648208618164,-6.150545597076416,-6.977010250091553,-6.678671360015869 -4354,4354,P253G,0.014790078,-0.0018652620000000001,-0.049057535,0.002782417,-0.466278219,-0.009619127,0.024744547000000002,0.004835608,-0.031698803,-0.023866526000000002,0.020136002,-0.06948186099999999,-0.028633207999999997,-0.042294427999999995,0.047859262,-0.255710732,-0.6768457059999999,1.590887955,2.182387887,-3.819347734,-4.323993485,-2.843828758,-3.4975970839999997,-6.4368558039999995,-1.994463539,-3.983722937,0.43485368799999996,-5.082223415374756,-2.7085037231445312,-4.5226030349731445,-6.442251682281494,-5.954878807067871 -4355,4355,P253F,0.08637020699999999,0.04552739099999999,-0.030415171,0.042751587,-0.23065470899999999,-0.021286167999999998,0.099053573,0.073686841,0.20582520899999998,-0.043546579,0.13460136,-0.12394150400000001,0.063111163,-0.067574285,0.153077459,-0.263778346,-0.197531072,1.50029886,2.081902257,-8.873667328,-9.000127014,-6.870024422,-9.803485611000001,-10.71438654,-7.980313057,-8.734950608,-5.071265036000001,-7.403153419494629,-7.940915107727051,-8.134111404418945,-9.681917190551758,-10.731491088867188 -4356,4356,P253I,-0.052900301,0.11142724400000001,-0.0005629319999999999,-0.022065442999999997,-0.22074127,-0.028692014,-0.026009928999999998,-0.079790672,-0.096086603,0.08386577,0.13898871699999998,0.047468435999999996,-0.048594299,-0.069462703,0.025331818,-0.18886222800000002,-0.252620312,1.0882857670000001,1.90400814,-6.516913193,-6.9271157610000005,-4.911028755,-6.550408401,-8.411796066,-5.78421698,-7.170860652999999,-2.8020701939999997,-6.478217601776123,-7.233200550079346,-6.55057954788208,-8.078400611877441,-9.02877426147461 -4357,4357,P253H,0.050061925,-0.020731181,-0.006215015,0.024640594,-0.214422683,-0.039543166,0.016651223,0.08347262700000001,0.036764458,-0.073884033,0.032421671,-0.051240495999999996,0.038810467,-0.031895146,0.081176333,-0.17040193399999998,-0.258443431,1.4269563269999999,2.188234796,-4.711947948,-4.4371819310000005,-2.842131012,-5.842531395,-6.738975998,-3.698919403,-5.029431052,-0.631755492,-5.47654914855957,-5.546581268310547,-5.930911540985107,-8.192948341369629,-8.287782669067383 -4358,4358,P253K,-0.092022147,-0.033574459,-0.054573214,-0.040507182999999995,-0.549782588,0.063369012,0.0048484290000000005,-0.188892723,0.088431145,-0.104156124,0.037007206,-0.07889655599999999,-0.030249871,-0.123460624,0.04244625900000001,-0.238758368,-0.860806807,1.510961587,2.0967055219999997,-2.913037788,-3.070343346,-1.426672089,-3.547653954,-4.621201019,-1.899318535,-2.8863490460000003,1.003505347,-5.133213520050049,-5.477771282196045,-3.799941062927246,-6.948398113250732,-7.414803504943848 -4359,4359,P253M,0.011257346000000001,0.062117335,0.042856146,0.055912677,0.013571918,0.020054438,0.041366539,-0.018851846999999998,-0.042366555,0.120359488,0.0038751809999999997,-0.007808219,0.093520511,0.014954031999999999,0.096871321,0.025433382999999997,0.0017104520000000001,1.10740376,2.6695471040000003,-6.381919814,-6.808675606,-5.068576752,-6.370821136,-8.360120987,-5.3014045869999995,-7.353758407000001,-3.55905309,-7.56312894821167,-7.544257640838623,-7.554348945617676,-8.727110862731934,-9.617960929870605 -4360,4360,P253L,0.054985975,0.016183613,-0.050710886,0.008525789,-0.198231325,-0.008437615,0.054447052999999995,0.055524896,-0.002668142,-0.051648933,0.084016159,-0.111925115,0.010503343,-0.085831741,0.102883318,-0.166853784,-0.229608865,1.489267683,2.216193413,-5.087231546,-5.624578377000001,-3.493128212,-4.831398544,-7.402409355,-4.084643242,-5.850249882000001,-2.407344024,-5.856963157653809,-6.6796369552612305,-6.0813679695129395,-7.85661506652832,-7.954909801483154 -4361,4361,P253N,-0.006848344,0.016641298,-0.056580200000000004,0.097143385,-0.39741796700000004,-0.09996572699999999,0.112281499,-0.125978186,0.018594545,-0.018322392,0.051604987000000005,-0.096802314,-0.016358086,0.024505712000000002,0.169781058,-0.301150717,-0.49368521600000004,1.577421983,2.1122256569999998,-4.767049362,-3.783810677,-3.06268428,-6.59066259,-6.174505005,-4.223584259,-5.553341644,-0.7335990040000001,-5.113636493682861,-5.157708644866943,-5.6579909324646,-7.01600980758667,-7.209334850311279 -4362,4362,P253Q,0.049462871,0.018768349,0.029219521000000002,-0.014594246000000002,-0.396652916,-0.016140171000000002,0.033955874,0.064969868,-0.018417553,0.03454081,0.002995888,-0.000623607,0.059062649,-0.065999914,0.036811422,-0.235513227,-0.557792604,1.47460071,2.099275672,-3.332736195,-3.818956291,-1.7856598430000001,-3.825013626,-5.003486649,-2.230564568,-4.304783016,0.111381239,-4.797141075134277,-4.900949478149414,-4.614260673522949,-6.828588008880615,-6.744802474975586 -4363,4363,P253S,0.021242384,0.011666626999999999,-0.022071991000000003,0.027149309,-0.227414653,-0.015050787,0.02595522,0.016529548,0.023405588999999997,-0.027351708,0.050684962,-0.06093806400000001,0.016794083,-0.028061983999999998,0.08236060099999999,-0.169561093,-0.285268213,1.340402463,2.111688785,-2.2974713209999997,-2.227312393,-1.1571842270000001,-3.114279068,-2.641502159,-2.3470787580000003,-3.362897701,-0.014898804,-4.634884834289551,-3.814974546432495,-4.516650199890137,-5.849330425262451,-5.571982383728027 -4364,4364,P253R,-0.01401257,0.000250127,-0.042228405,0.018737438000000002,-0.565616356,-0.017677892,0.007706467,-0.035731606,0.021077841,0.008755427,-0.008255173000000001,-0.035142524,-0.049314285,-0.014739888999999999,0.052214765,-0.26860275899999997,-0.862629952,1.429014611,2.027179926,-3.707861328,-4.537049622,-1.510236343,-4.354681587,-6.0204432070000005,-2.1168958819999997,-4.252243317,1.005104819,-5.163717269897461,-4.488651752471924,-4.077047824859619,-7.634532451629639,-7.989161491394043 -4365,4365,P253T,0.029179069,0.046690771,0.002184782,0.065396688,-0.715523995,-0.045748185,0.030413206,0.027944932000000002,-0.030347032000000003,0.021858982000000002,0.071522559,-0.028366551,0.032736114,0.006250628,0.12454274800000001,-0.357183928,-1.073864062,1.51645171,1.986816098,-3.0528271989999998,-2.831913132,-1.569379105,-3.669974571,-4.9193311689999994,-2.273538017,-4.845598482,0.110036682,-4.9611968994140625,-4.3896403312683105,-4.777921676635742,-6.131062984466553,-6.408421039581299 -4366,4366,P253W,-0.037056808,-0.030596262000000003,-0.04554463,0.0171003,-1.079928286,0.043655482999999995,-0.028074735,-0.046038881,0.011120805,-0.048948877,-0.012243647,-0.050521588,-0.040567672,-0.014243499,0.048444098,-0.8165514209999999,-1.34330515,0.898412697,1.4184675169999998,-8.975329468,-9.349648933,-6.853794296,-9.876669571,-10.61643506,-8.18009948,-9.538299652000001,-7.362813533,-9.337164878845215,-9.512434959411621,-9.54749584197998,-11.006746292114258,-12.626466751098633 -4367,4367,P253V,0.021819572000000002,0.044654135,-0.047024014,0.066707238,-0.549257937,0.011396641,0.018737277,0.024901866,0.048471333,0.016058476000000002,0.073249793,-0.05801815900000001,-0.036029869,0.004644354,0.128770122,-0.249636947,-0.848878927,1.286508962,1.9345644640000002,-4.785800818999999,-5.177059723,-3.861473328,-4.590934937,-6.702271935,-3.597264175,-5.668579191,-1.8037061419999998,-5.846708297729492,-5.766616344451904,-5.4558186531066895,-6.645735263824463,-7.912496566772461 -4368,4368,P253Y,-0.0745008,-0.058527189,0.030254291000000003,0.031478213,-0.29574585600000003,-0.006751381999999999,-0.115947414,-0.033054185,-0.104519771,-0.073884033,-0.043170344000000006,0.004002742,0.05650584,-0.016761403,0.079717829,-0.177187923,-0.41430378799999995,1.544767194,2.303887595,-7.938247844,-7.447140922999999,-5.782701148999999,-9.386935692,-9.808919777,-7.265541679,-7.4464071039999995,-3.1684811739999996,-7.658336639404297,-7.8157758712768555,-8.028580665588379,-9.717829704284668,-10.945612907409668 -4369,4369,S254A,-0.077292263,0.000983708,-0.011320321000000001,-0.008467373,-0.031046557000000002,-0.023272498,-0.051319814000000005,-0.103264712,-0.07277927,-0.014930615,0.016898031,-0.023408427000000002,0.000767785,-0.013541043000000001,-0.003393703,-0.024549009,-0.037544104,1.385481931,2.654527629,-1.12795589,-0.829928703,-1.470694664,-0.647948105,-1.004361473,-1.686846504,-1.3678449959999999,0.538437309,-1.9560692310333252,-1.9246271848678589,-2.8739676475524902,-0.9654045104980469,-3.53560733795166 -4370,4370,S254C,0.310455027,-0.007004982,0.037133592,0.06626970900000001,-0.036287842,0.025207875,0.114301004,0.50660905,0.038001544,0.006030164,-0.020040128,0.027525572999999998,0.046741610999999995,0.038016438,0.09452297900000001,-0.023634229,-0.048941455,1.256963482,2.472774749,-5.4967860470000005,-4.049459488,-7.586181007,-4.726432991,-6.1485175629999995,-4.973339188,-5.43698261,-1.797668773,-6.518205642700195,-5.9351911544799805,-7.2222676277160645,-7.579543113708496,-9.637325286865234 -4371,4371,S254E,-0.036899554,0.031168168,-0.013442751999999999,0.014938513,0.049921103,0.024241605,0.03242132,-0.106220428,-0.056385240999999996,-0.04216237,0.104498706,-0.065669484,0.038783981,-0.01452663,0.044403655,-0.000777732,0.10061993699999999,1.2700313540000001,2.57458469,-2.275311464,-2.09893573,-2.166376701,-2.6496388090000003,-2.011647804,-2.449958275,-2.429855257,-0.758284086,-5.404192924499512,-7.199925899505615,-5.642861843109131,-4.285454750061035,-7.320620059967041 -4372,4372,S254D,-0.12638976300000002,0.016349653999999998,0.02597998,0.021326805,-0.07671244299999999,-0.025699132000000003,-0.08366295,-0.16911657600000002,-0.029026872000000002,0.049999355,-0.017300047,0.011272283000000001,0.040687677,0.027890468999999998,0.01476314,-0.006025949,-0.14739893699999998,1.172658877,2.5299513719999998,-4.684418915,-3.650573128,-5.421602524,-4.458497086,-4.533296173,-5.358125664,-4.881307076000001,-1.772220686,-5.802055358886719,-6.999480247497559,-5.9833784103393555,-4.540461540222168,-7.602171897888184 -4373,4373,S254G,-0.052655547000000004,0.0028985129999999997,0.016510204,-0.0013683579999999999,-0.019009003,-0.0022381289999999997,-0.015467227,-0.089843866,-0.033770192000000004,-0.044732567,0.050529592000000005,-0.032511038,0.065531445,-0.019266923000000002,0.016530208,-0.011016166,-0.027001839,1.1952619359999999,2.412936074,-5.080683073,-3.9800802,-6.4954331970000005,-5.106406624,-4.4109543989999995,-5.410540947,-5.00683039,-1.255956735,-4.283320426940918,-4.101285934448242,-4.361650466918945,-4.070237159729004,-6.038616180419922 -4374,4374,S254F,-0.11780489300000001,0.051457261,0.023072255,0.042608705999999996,-0.852830984,-0.031193571,-0.058092727000000004,-0.177517058,-0.07567012,0.039758914,0.063155607,0.082724514,-0.036580005,0.10386266699999999,-0.018645256000000002,-0.425648374,-1.2800135940000001,0.595856494,1.438500881,-8.330261441000001,-6.6255947420000005,-10.31722294,-6.750500113999999,-9.413014572,-8.544974838,-5.956460912000001,-2.627009621,-6.692211151123047,-6.916219711303711,-7.250216960906982,-7.455936431884766,-10.221375465393066 -4375,4375,S254I,-0.05661823,-0.007425204,0.015648411,0.010908863000000001,-0.158424919,0.027667099,-0.019645645,-0.093590815,0.052220296,-0.039071293,0.024220885,0.054534992000000004,-0.023238171000000002,-0.047313664000000005,0.06913139,-0.179074913,-0.137774924,1.54949492,2.295877772,-6.413307266,-5.588095711,-6.719466048999999,-6.170454491,-7.098816482999999,-6.489703597999999,-5.363408223,-1.9430444119999999,-6.145328998565674,-6.0399298667907715,-6.238572120666504,-6.285549163818359,-8.683719635009766 -4376,4376,S254H,-0.14316616,-0.032391106,-0.009945834,-0.036929614,-0.08558390800000001,0.022354368,-0.09773569800000001,-0.18859662100000002,-0.025337417999999997,-0.042921626,-0.021860585,-0.069342474,0.04945080599999999,-0.014680426000000002,-0.059178802,-0.066988605,-0.10417921,1.425478475,2.504198249,-6.384943343,-4.006898911,-8.826061722,-5.521926346,-7.1032286760000005,-6.466601058999999,-4.148203262,0.65483358,-4.972960948944092,-6.20011568069458,-5.6920318603515625,-5.821141242980957,-8.229181289672852 -4377,4377,S254K,-0.004400338,0.002332747,0.055228118,0.041486487,-0.020201976,-0.013236842,0.11082558,-0.119626255,0.026308294,-0.08791986,0.09258535400000001,-0.023139901,0.133596137,-0.001270367,0.08424334,-0.05072504,0.010321089,1.3722242519999999,2.534436454,-3.912220656,-2.7898872530000003,-4.203199333,-4.258769264,-4.727215233,-3.582032196,-4.073441423,0.055035774,-5.533900737762451,-6.08007287979126,-4.903354644775391,-4.620469093322754,-7.066122531890869 -4378,4378,S254M,0.014182076000000002,-0.013020901999999999,0.086502743,0.050960585999999995,-0.089127927,0.065584637,0.081380934,-0.053016782,-0.00674035,-0.042560988,0.016519185,-0.031740073,0.204745558,0.005569058000000001,0.096352114,-0.093974128,-0.084281725,1.383365659,2.376571656,-7.348018112,-6.188415512000001,-6.8590221179999995,-7.502510902,-8.200231255,-7.989910774,-5.539979402,-2.427726963,-6.108073711395264,-6.090701580047607,-7.023191928863525,-6.180732727050781,-8.070526123046875 -4379,4379,S254L,-0.128108364,-0.029747237000000003,-0.029201441,-0.056561532000000005,-0.121766338,0.01030016,-0.080694876,-0.175521852,-0.02713321,-0.032744969,-0.026749505,-0.033856076,-0.024546806,-0.031927867,-0.081195197,-0.073077219,-0.170455457,1.4461091719999999,2.479097431,-6.851155567999999,-5.930336562999999,-5.981504997,-6.917216957000001,-8.293844352999999,-7.1328749689999995,-4.661455064,-1.4920711309999999,-4.802138805389404,-4.952120780944824,-5.072601318359375,-5.020708084106445,-8.12480640411377 -4380,4380,S254N,-0.11607370300000001,0.032984761,0.053035575,-0.016518827,-0.060392050999999995,0.037065539,-0.067589645,-0.164557761,0.014983634,0.01353778,0.052431741,-0.002000404,0.108071554,0.034216772,-0.067254425,0.055763259,-0.176547361,0.961157833,2.6655015509999997,-4.63287961,-3.692384003,-5.7415316160000005,-4.403483856,-5.013109245,-4.313889328,-5.130544424,-1.37988286,-5.435748100280762,-5.997934341430664,-5.615269184112549,-5.106609344482422,-6.852597713470459 -4381,4381,S254Q,-0.19192203100000002,-0.070223585,-0.019689468,-0.0066666569999999994,-0.011445583999999998,0.085227481,-0.144395188,-0.23944887399999998,-0.0018177070000000002,-0.035129107,-0.10531806199999999,-0.003268418,-0.036110517,0.048743025,-0.062076337999999995,-0.002471212,-0.020419955,1.671448915,3.643209181,-5.084573808,-3.38113076,-6.073376801,-5.507773605,-5.093374237,-5.367213638,-4.2972803530000006,-0.5550621579999999,-4.370860576629639,-5.622806549072266,-4.57293701171875,-4.137770652770996,-6.703976154327393 -4382,4382,S254P,-0.09495685599999999,0.009868507,0.0013071019999999999,-0.009858871,-1.092810178,0.00704661,-0.056978807,-0.132934904,-0.018359633,-0.024260001,0.043997014,-0.028411304,0.031025507999999997,-0.015586012,-0.00413173,-0.705828329,-1.4797920269999998,0.850535332,1.430519715,-1.38198976,-0.574218079,-1.5302118230000001,-1.114420296,-2.264148735,-1.4269498669999998,-1.873583465,2.769673122,-1.9408130645751953,-0.4274883270263672,0.03402996063232422,0.4327854514122009,-4.150092124938965 -4383,4383,S254R,-0.013196531000000001,0.012912136000000001,0.011631754,0.00791608,-0.02496754,0.012445058,-0.030680943999999998,0.004287882,-0.040970108,0.007179036,0.018645236000000003,0.015670646,0.007592860999999999,6.63e-05,0.015765859,0.003777235,-0.053712314000000004,1.112342145,2.40559552,-5.036340324,-2.818049461,-6.141960625,-5.205154694,-5.237223244,-5.779313599,-4.229749675,1.5283865419999998,-4.854933261871338,-5.531106472015381,-4.020270824432373,-5.136504173278809,-7.608278274536133 -4384,4384,S254T,-0.053628812000000005,0.024137711000000003,0.026426815,-0.026935808999999998,-0.00718497,0.003629904,-0.022896929,-0.084360694,0.002081122,0.00035196699999999996,0.047923454000000004,0.007267404,0.045586225,-0.039285253,-0.014586365,0.014073246000000001,-0.028443186000000002,1.231938942,2.6546723969999997,-1.221565979,-0.965376274,-1.25037841,-1.492573975,-1.26765583,-1.1318454059999998,-2.52171576,0.260172409,-4.403389930725098,-4.411194801330566,-4.786274433135986,-4.363450050354004,-4.432135581970215 -4385,4385,S254W,-0.08612675800000001,-0.065814395,-0.031431493,-0.041933604,-0.424733032,-0.06300693,-0.009136165,-0.163117351,0.128188344,-0.007969271,-0.12365951800000001,-0.026261392,-0.036601594,-0.043171811,-0.040695397,-0.146355995,-0.703110068,1.39563807,2.214735936,-8.229243013,-6.465822319,-9.753524216,-7.393716789,-8.563747414,-8.969404327000001,-5.677194232000001,-2.8914114719999997,-7.837925434112549,-8.545167922973633,-7.772955417633057,-9.047906875610352,-11.371971130371094 -4386,4386,S254V,-0.091244487,-0.004765805,-0.02258463,-0.002045327,-0.074877584,0.021425577999999997,-0.052848544000000004,-0.129640429,-0.013734615,-0.03485969,0.02532808,-0.047190175,0.002020915,-0.017494421,0.013403768,-0.040700344,-0.10905482300000001,1.224566242,2.396587879,-4.405721613,-4.012061165,-4.500886276,-4.491062187,-4.130973648,-4.893624786,-4.032980198,-0.545677014,-4.851740837097168,-4.547664165496826,-5.1293625831604,-4.510650634765625,-7.256752014160156 -4387,4387,S254Y,-0.16885800399999998,-0.08137451799999999,-0.018126134,-0.013225464,-0.6472753139999999,0.089898805,-0.060481899000000006,-0.277234109,0.002483705,-0.110782743,-0.051966293,-0.086302352,0.050050085,-0.067942287,0.04149136,-0.418995125,-0.875555503,1.54175309,1.9502742030000002,-8.201130724,-5.500169571,-11.64448792,-6.505533691,-8.652663627999999,-8.702798813,-5.678352814,-1.017984998,-6.783816337585449,-7.1014909744262695,-7.2917866706848145,-7.620388031005859,-10.042424201965332 -4388,4388,R255A,-0.043378499,-0.021511047999999998,-0.031945101000000004,-1.2166784929999999,-2.085895793,0.01367479,-0.052926667999999996,-0.033830329,0.015042969,-0.0047271909999999995,-0.038294904,-0.018390781999999998,-0.045499419000000006,-0.63709957,-1.796257415,-2.058506898,-2.1132846869999997,1.8133363630000001,1.39882025,-6.764009561,-7.458838936,-6.545634781,-5.9664639820000005,-7.151590378,-6.69751973,-5.4170065979999995,0.616571469,-5.962402820587158,-8.615072250366211,-4.279364109039307,-8.143402099609375,-3.743948459625244 -4389,4389,R255C,-0.020210327,-0.031898994,-0.026925435,-1.112463686,-2.442376616,0.024466855,-0.016416206000000003,-0.024004447999999998,0.058054617999999995,0.005031494,-0.068829481,-0.013214073,-0.040636796,-0.625969636,-1.598957735,-2.132883613,-2.751869619,1.7511951909999999,1.3551677469999999,-8.855382387,-10.32537157,-9.100717941000001,-8.611462105,-7.461926361000001,-8.777433952,-7.026274695,-0.7868193720000001,-7.975908279418945,-9.737140655517578,-6.369936943054199,-8.747697830200195,-7.3335394859313965 -4390,4390,R255E,-0.08684752,-0.09743882400000001,-0.166490792,-1.75262398,-2.826118507,-0.067699275,-0.09102025400000001,-0.082674785,-0.014210572,-0.07037572,-0.124501927,-0.08964716199999999,-0.24333442100000002,-1.232235937,-2.273012022,-2.675996114,-2.9762408989999996,0.775369457,0.732449195,-10.56357408,-11.56331415,-10.35561404,-10.412142999999999,-11.56554111,-8.921258102000001,-8.530136,-3.638000043,-8.1436185836792,-11.35059928894043,-7.02280330657959,-10.183530807495117,-7.7398176193237305 -4391,4391,R255D,-0.039089437000000005,-0.90444169,-2.10411754,-2.51920936,-2.5773365790000002,0.014710282,-0.020923762,-0.057255112000000004,0.045977008,-0.403046202,-1.405837178,-2.371060997,-1.837174082,-2.45542186,-2.58299686,-2.537454201,-2.617218957,0.339508504,-0.46896967100000003,-11.12075656,-12.18770659,-10.55042397,-10.67306437,-11.8287181,-10.36386977,-9.405761067,-5.994013933,-8.529244422912598,-11.613495826721191,-7.347671985626221,-10.459495544433594,-7.437873840332031 -4392,4392,R255G,-0.035516339,-0.019530771000000002,-0.988709271,-1.929591186,-2.607993029,-0.02390448,-0.030780765,-0.040251912,-0.049704622000000004,0.00465833,-0.043719870999999993,-0.44858106200000003,-1.528837479,-1.77640764,-2.0827747309999998,-2.366595469,-2.8493905880000003,1.67396494,0.820922088,-9.823540735,-10.21552294,-10.01343985,-9.269761878999999,-9.988492256,-9.630486748,-7.823932748,-1.89537733,-7.3129754066467285,-9.49592399597168,-6.08066463470459,-9.171517372131348,-5.097382545471191 -4393,4393,R255F,0.023336492,0.009398449,-0.9195616259999999,-1.885576062,-2.8763539939999996,-0.016047875,-0.000824997,0.047497980999999995,-0.049030082,0.08058001599999999,-0.061783119000000004,-0.491628169,-1.347495083,-1.948901035,-1.822251089,-2.252782125,-3.499925862,1.5994211680000001,0.7441130220000001,-6.700698158,-7.297774948,-6.17204464,-6.26757737,-7.3728741,-6.393219734,-5.224133976,2.26768469,-6.712186336517334,-9.290361404418945,-3.91502046585083,-9.674484252929688,-7.717287540435791 -4394,4394,R255I,-0.05677605,-0.001571475,-0.047934729,-0.296151688,-1.6814741469999999,-0.11027069999999999,-0.157075992,0.043523893,-0.048329183,0.028180258,-0.031323207,-0.017357306,-0.078512151,-0.025329822999999998,-0.566973553,-2.200783849,-1.162164445,0.6938073859999999,1.283077579,-6.17004744,-8.280233871,-5.5209947360000005,-5.557661102000001,-7.311126709,-4.180220779,-3.628858703,3.0138306889999997,-6.259367942810059,-7.838291645050049,-1.5612720251083374,-9.082895278930664,-6.450504302978516 -4395,4395,R255H,-0.029324962000000003,-0.016389397,-0.029693857,-0.47616995100000004,-1.895191031,-0.029426251,-0.043124813,-0.01552511,-0.053482375,0.00028271599999999997,-0.03306151,-0.002237421,-0.057150293,0.005624116,-0.957964017,-1.614926104,-2.175455957,0.592780347,1.309902125,-3.7998659060000004,-3.8010724330000003,-3.650109695,-4.00339782,-4.423513123,-3.1212364580000003,-5.767567696,-1.120295891,-6.036767959594727,-7.120795249938965,-3.9459519386291504,-6.888019561767578,-5.775338172912598 -4396,4396,R255K,0.029245342999999997,-0.05690964900000001,-0.082790346,-0.03681639,-0.027408632000000002,-0.033182869,0.003948473,0.054542212,0.011837503000000001,-0.061972562,-0.051846736,-0.009487961999999999,-0.156092729,-0.06422635900000001,-0.00940642,-0.059977113,0.00515985,1.224864098,2.236257546,-6.604129267999999,-6.487511215,-6.709932335,-6.760024948,-6.94784359,-6.115334251,-7.153557987999999,-2.07633807,-5.620651721954346,-5.580263137817383,-4.531260013580322,-5.855474472045898,-4.538028717041016 -4397,4397,R255M,-0.001651074,0.032912732,-0.028043943999999998,-0.245939811,-2.10091888,0.016102622,-0.017103208999999998,0.013801062,0.048355164000000006,0.010065858,0.055759605999999996,-0.076343319,0.020255431,-0.018427231000000002,-0.47345239100000003,-1.648058485,-2.553779275,0.748983301,1.316677466,-7.8767915539999995,-9.229757027,-8.574009911000001,-7.415159111,-8.303513794,-5.861517929,-4.889192212,0.146158974,-7.359401702880859,-8.427289009094238,-3.3628616333007812,-9.160958290100098,-7.334334373474121 -4398,4398,R255L,-0.032645135,-0.026034757999999998,-0.028104442,-0.378602858,-1.841853145,0.036097152,-0.040346072000000004,-0.024944197999999997,-0.009133783000000001,-0.021284214,-0.030785302,-0.009055568,-0.047153315,-0.053666649000000004,-0.703539067,-1.65395977,-2.02974652,0.707906748,1.313784227,-5.912760696,-6.981705872,-7.856859055,-5.39116188,-3.74528701,-5.588789665,-4.0808625869999995,2.723804346,-5.033876895904541,-7.076530933380127,-1.393798828125,-7.38640832901001,-5.72279167175293 -4399,4399,R255N,-0.014402288000000001,-0.035500676,-1.025941744,-1.85328601,-2.618899902,-0.009017172,-0.016501092,-0.012303483,0.01147398,-0.032706447,-0.038294904,-0.7371536390000001,-1.314729848,-1.997605761,-1.708966258,-2.079638101,-3.1581617019999997,3.578366533,2.24752255,-10.07719632,-10.0060732,-10.40572917,-10.10155185,-11.30015036,-8.57247702,-9.378161197,-5.85321931,-7.504067420959473,-9.317384719848633,-5.895920753479004,-8.696122169494629,-5.953757286071777 -4400,4400,R255Q,-0.040554365,0.008872005,0.00031886400000000003,-1.258097567,-2.147603701,0.003432691,-0.049386124,-0.031722605,-0.033629801,0.037599935,-0.019855925,0.028709667999999997,-0.02807194,-0.746093405,-1.770101729,-1.782368254,-2.5128391480000003,2.072798894,1.5768677709999999,-6.589488536,-7.422879501000001,-6.996257385,-6.000133591,-6.953653572,-5.574518631,-7.279640937000001,-2.224759213,-6.340620517730713,-8.581850051879883,-4.517964839935303,-6.107735633850098,-5.520412445068359 -4401,4401,R255P,-0.0070594640000000005,-1.750263954,-2.222086659,-2.2804655190000003,-3.355304615,-0.020685797,-0.021377765,0.007258838,-0.085706332,-1.830525753,-1.670002154,-1.991456736,-2.452716581,-2.110579705,-2.450351332,-2.9707632960000003,-3.739845934,-0.30828932,-1.0981262390000002,-11.0943509,-11.60364522,-11.20846322,-10.58815392,-11.53673878,-10.53475333,-9.405761067,-5.994013933,-5.043636798858643,-9.206713676452637,-6.021117210388184,-9.266056060791016,-3.349522113800049 -4402,4402,R255S,-0.01805155,-0.003711798,-0.024266617999999997,-1.248414034,-2.797274372,-0.014074366999999999,-0.017392992,-0.018710108,-0.023558977999999998,-0.016855271,0.009431676,-0.023265532999999998,-0.025267702000000003,-0.8048201420000001,-1.692007926,-2.701987299,-2.892561445,0.798030178,0.790074973,-8.947214819,-8.844811722000001,-8.350699028,-8.574395492999999,-9.854117287000001,-9.112050567999999,-7.292145709,-2.297251214,-5.611382484436035,-8.532546997070312,-5.0473127365112305,-8.267561912536621,-3.260434150695801 -4403,4403,R255T,-0.002236586,0.004703486,-0.072025036,-1.067756336,-2.500235922,-0.077486434,-0.017656074,0.013182902,-0.035228051,0.044229395,-0.034822424,-0.039362182,-0.104687889,-0.467505021,-1.66800765,-2.011935359,-2.988536485,1.689861255,1.3828266130000002,-7.327070472999999,-8.372932175,-6.30394352,-7.0119114,-7.762431702000001,-7.184133567999999,-5.652982322000001,-0.946084923,-6.450392246246338,-8.690837860107422,-4.528778553009033,-8.636889457702637,-4.54957389831543 -4404,4404,R255W,-0.011575321999999999,-0.6669954579999999,-1.952554295,-2.033142725,-2.741784941,0.054773447,-0.009266896,-0.013883747,0.007532685999999999,-0.255093672,-1.078897244,-1.947716409,-1.95739218,-1.855986013,-2.210299436,-2.415139608,-3.068430274,0.959112405,-0.092401791,-5.317202786,-6.016811287,-5.845949615,-5.247691368,-6.065923088,-3.409638573,-4.450118478,0.47834255600000003,-7.706843852996826,-9.803013801574707,-4.1646728515625,-8.808675765991211,-8.381157875061035 -4405,4405,R255V,-0.043340984000000006,0.006080136,-0.009585314000000001,-0.26264843,-1.555218978,-0.0067246630000000005,-0.059685679000000005,-0.026996289,0.0018514,0.045123859,-0.032963587,0.035183174,-0.05435380099999999,-0.008278801,-0.517018058,-1.4660982919999999,-1.6443396630000002,0.565240506,1.314980287,-5.568502372999999,-6.840176743,-5.529785744,-4.516499321,-6.297876822999999,-4.658173233,-4.015973635,2.625701946,-6.07066535949707,-7.95143985748291,-3.1415762901306152,-8.582813262939453,-6.006085395812988 -4406,4406,R255Y,-0.001309946,-0.087036091,-1.401495964,-2.5167950980000002,-2.256511268,-0.043019517,-0.0008956639999999999,-0.001724227,0.0565202,0.024387269,-0.198459451,-1.1924951190000002,-1.6104968080000002,-2.00385471,-3.0297354860000003,-2.261978309,-2.251044226,3.124234435,1.6524003859999998,-4.858955217,-5.413916603,-4.329925949,-5.657278549,-5.138023796000001,-3.755631187,-4.463659044,3.2307122089999996,-7.036896228790283,-8.88065242767334,-3.729175090789795,-9.726597785949707,-7.688321590423584 -4407,4407,I256A,0.051827108,0.032781448,0.028515986,-0.026911959,-1.7805132590000001,-0.007461,0.085134343,0.018519873,0.014202818,-0.013334348999999999,0.078897244,-0.017426233,0.074458205,0.033923297000000005,-0.087747214,-1.5821775040000001,-1.978849013,0.62849743,1.3126328390000002,-7.433812068,-6.496695755,-5.36975872,-12.23994312,-7.306442382999999,-5.75622036,-4.924034397,0.251557375,-5.047377586364746,-4.557323932647705,-3.9322550296783447,-5.338873863220215,-6.734591007232666 -4408,4408,I256C,0.198037186,0.06620712200000001,-0.020877817,0.063026065,-1.213999249,-0.061310116,0.207916109,0.188158262,0.042913202000000004,0.031156301,0.101257943,-0.07282441099999999,0.031068778,0.031302258,0.094749871,-1.3230322,-1.104966297,0.7064284190000001,1.331148838,-9.957338533,-8.111836128,-7.830223701,-13.65027501,-9.297541077,-10.89681675,-6.806913344,-3.8020282260000005,-7.601968288421631,-9.502962112426758,-6.948239803314209,-8.047260284423828,-10.503703117370605 -4409,4409,I256E,0.005147858,-0.169800372,-1.443462953,-2.4045005180000003,-2.9466816110000003,0.014501176000000001,0.026545742999999997,-0.016250028,0.003828572,0.041374097,-0.38097484,-1.305857327,-1.581068579,-2.392062357,-2.4169386790000003,-3.130096384,-2.7632668380000003,0.47201495,0.05578944,-12.655432800000002,-11.06546815,-9.927366623,-16.17915937,-11.86462607,-14.24054379,-7.205438059,-4.3833381010000005,-10.345678329467773,-10.819645881652832,-8.26557445526123,-11.778057098388672,-12.834966659545898 -4410,4410,I256D,0.103227099,-1.7086673369999998,-1.665553438,-2.411804575,-2.347045758,-0.043637456,0.08708009900000001,0.119374099,-0.11336628800000001,-1.276122644,-2.141212029,-1.683607971,-1.647498904,-2.20554157,-2.618067579,-2.3415156059999997,-2.352575909,4.026599353,1.856402392,-13.93676651,-11.8235308,-11.46996103,-17.81575994,-13.22846011,-15.34612065,-8.657203444,-6.396043462000001,-10.9384126663208,-11.17321491241455,-9.267878532409668,-10.907625198364258,-12.587911605834961 -4411,4411,I256G,0.052258855,0.028385392000000002,-0.757248183,-1.5946151080000002,-2.507533621,-0.049460732,0.077851455,0.026666254,-0.026400958,-0.013208397,0.06997918,-0.41180759299999997,-1.102688772,-1.3904592009999999,-1.798771015,-2.286101082,-2.72896616,2.49432858,1.5001892330000002,-11.485227900000002,-9.447622062999999,-8.45546917,-16.70241387,-11.17613887,-11.64449554,-6.895650516,-3.9015460319999997,-8.152782440185547,-7.37031888961792,-7.11575984954834,-9.117549896240234,-10.376029014587402 -4412,4412,I256F,0.036034788,-0.014061128999999999,-0.049811852999999996,-0.010366645,-1.443576474,-0.041818615,0.044981069000000005,0.027088506000000002,0.030505328999999998,-0.05903768400000001,0.030915427000000002,-0.068583002,-0.031040703,-0.0053877740000000006,-0.015345515,-1.400637058,-1.486515889,0.7526660709999999,1.3306146890000001,-4.65080755,-3.05035511,-3.6003967439999998,-7.014225288,-4.731539215,-4.857521393,-4.203818676,-1.6960814919999998,-5.482403755187988,-6.496468544006348,-5.568948745727539,-5.934916973114014,-6.3839111328125 -4413,4413,I256H,-0.021972134,-1.0681758559999999,-2.2196449990000002,-2.216740859,-2.9785882989999997,-0.07486626,-0.060603227999999995,0.016658961,-0.008011118000000001,-0.9459042590000001,-1.190447453,-2.149269603,-2.290020395,-2.495111943,-1.938369775,-2.631085979,-3.3260906180000003,0.566180384,-0.60104993,-13.47177684,-11.87922249,-9.942826744,-16.64503691,-12.14428346,-16.747514600000002,-7.782838145,-5.347386473,-9.076652526855469,-8.967793464660645,-6.357146739959717,-9.387463569641113,-11.658700942993164 -4414,4414,I256K,0.038237877,-1.798913843,-1.9799437119999999,-2.4831567999999997,-2.778477635,-0.066418375,0.056527047999999996,0.019948705,-0.033396951,-1.825098023,-1.772729662,-2.01870353,-1.9411838940000001,-2.5406371290000003,-2.425676471,-2.852702424,-2.704252845,-0.6658032389999999,-1.079945192,-13.47039813,-11.23474399,-10.72886097,-16.4193326,-11.84661171,-17.12244137,-8.655554336,-6.402563799,-10.377272605895996,-8.53988265991211,-7.847931861877441,-9.93833065032959,-12.950006484985352 -4415,4415,I256M,0.023897928,0.021976203,0.019730043,0.019270673999999998,-0.857250367,-0.036256949,0.031290881,0.016504974,-0.041787621000000004,0.030489067999999998,0.013463336999999999,0.027548472999999997,0.011911613,0.041148049,-0.002606701,-0.6151655629999999,-1.0993351709999999,0.651828558,1.40046959,-5.291553201,-4.705943512,-4.7874640269999995,-6.685430229,-5.147003478999999,-5.1319247589999994,-5.331084218,-3.3502003960000004,-5.571756362915039,-4.851855278015137,-5.2403106689453125,-5.367674827575684,-6.206404209136963 -4416,4416,I256L,0.062237257000000004,-0.0015447629999999998,0.030183308,0.013804997,0.031781474,-0.031328813,0.07166125200000001,0.05281326099999999,0.013850616000000001,-0.034848385,0.03175886,-0.023670135,0.08403675,0.008429510999999999,0.019180482,-0.067632949,0.131195897,1.3746939669999998,2.393562958,-2.155813625,-1.446231056,-1.917934174,-2.847155426,-2.197679077,-2.37006839,-2.62369923,-0.37424145200000003,-2.943957567214966,-2.87831974029541,-2.903355836868286,-2.8349738121032715,-4.386791706085205 -4417,4417,I256N,0.055310147999999996,-0.562821218,-1.5490889890000001,-2.134230479,-2.785153544,0.002237775,0.024916569,0.085703727,0.041503807999999996,-0.235319632,-0.890322803,-1.606592786,-1.4915851919999998,-2.350375135,-1.9180858219999999,-2.486349171,-3.083957916,1.1475383479999999,0.056500034000000005,-13.0310496,-10.70349392,-10.14103234,-16.84293498,-12.34826796,-15.11951881,-8.127703815,-5.743080662000001,-9.574115753173828,-9.2438325881958,-8.079401016235352,-9.580347061157227,-11.74588680267334 -4418,4418,I256Q,0.071591266,-0.422695555,-1.6293270069999999,-2.225063146,-3.321413976,-0.026934062999999998,0.071663129,0.071519403,-0.00127215,-0.206701235,-0.638689874,-1.509451211,-1.7492028030000002,-2.177512846,-2.272613446,-3.0124568860000003,-3.6303710660000004,1.143897832,0.09258027099999999,-12.8270351,-10.87824624,-10.06537879,-16.14246511,-10.87328754,-16.17579784,-8.059054463999999,-5.732600856,-8.725202560424805,-8.066878318786621,-6.140095233917236,-9.228856086730957,-11.439933776855469 -4419,4419,I256P,0.016773053,-1.7050056740000001,-1.9394234890000002,-2.783821948,-2.8640804369999997,-0.013803252,0.027422807,0.006123298,-0.10586845800000001,-1.811646915,-1.598364432,-1.845551579,-2.033295399,-3.004307275,-2.563336621,-2.8392513160000004,-2.888909558,-0.076987674,-1.0948079309999998,-11.80632752,-10.51545722,-9.405980995,-15.86023612,-11.12081293,-12.12915034,-7.856497326,-5.6505433410000006,-6.550983428955078,-5.710676193237305,-9.451728820800781,-4.974279403686523,-9.613313674926758 -4420,4420,I256S,0.013634515,-0.09314712,-1.3456166330000001,-2.033570791,-2.7213869639999997,-0.025374945,0.030277408999999998,-0.00300838,-0.05700068,0.030353638999999998,-0.21664787800000002,-1.064450768,-1.6267824969999998,-1.987529516,-2.079612066,-2.600624807,-2.84214912,2.2374351480000003,0.9071752059999999,-10.03763713,-7.948071854,-7.537128479,-15.13409908,-9.138651497,-10.43023474,-6.506612854,-2.448623204,-7.056554317474365,-7.522673606872559,-5.604395866394043,-7.6311845779418945,-9.077601432800293 -4421,4421,I256R,0.024502272999999998,-1.7659977580000001,-2.034737441,-2.223594437,-3.003933659,-0.038277322,0.056633267,-0.007628721999999999,-0.101842839,-1.69165777,-1.840337745,-2.213086449,-1.8563884330000002,-2.111770758,-2.335418115,-2.694902825,-3.312964493,-0.21540336100000002,-1.0851002570000001,-14.00122744,-11.31260469,-10.91593624,-16.80795244,-12.68227671,-18.28736711,-8.739979436,-6.402563692,-9.327337265014648,-8.250524520874023,-6.4907331466674805,-9.914710998535156,-12.118866920471191 -4422,4422,I256T,0.043519472000000003,-0.028753043,-0.12651782,-1.80799367,-2.782825476,-0.036170131,0.054606880999999996,0.032432062000000005,-0.01449531,-0.060331857999999995,0.0028257729999999997,-0.053096995999999994,-0.199938644,-1.457112201,-2.158875139,-2.3712374869999997,-3.1944134639999997,0.856921096,0.720312134,-8.259118475,-6.6865898360000005,-6.272687027000001,-11.2548152,-7.358060715,-9.723439597999999,-5.733026662,-1.829980766,-6.274578094482422,-6.933323860168457,-5.470523834228516,-6.826326370239258,-7.273265838623047 -4423,4423,I256W,-0.0020921810000000002,-0.40051956200000005,-1.540245048,-2.117686485,-2.8866541430000003,-0.014054038999999999,0.013850848,-0.018035209,0.018394191,-0.11983741,-0.6812017140000001,-1.525344171,-1.555145924,-2.213609192,-2.021763777,-2.3495832269999997,-3.4237250589999997,0.859555605,0.045686776,-10.865573399999999,-8.677658821,-9.192047974,-13.90670571,-10.70988857,-11.84156593,-8.075393361,-6.07463222,-8.179591178894043,-9.485048294067383,-6.935072422027588,-10.090790748596191,-10.51936149597168 -4424,4424,I256V,0.08197183400000001,0.037195419,0.043297259000000005,0.054170102000000005,0.061372290999999995,-0.012270831999999999,0.10678802300000001,0.057155644000000005,0.028964366000000002,0.052220008,0.022170829,0.002612947,0.08398157,0.062097867,0.046242335999999995,-0.010173374,0.132917955,1.168857941,2.575663944,-3.1530383160000004,-2.0792405780000003,-3.033088989,-4.514507225,-5.044824028,-1.093530762,-2.8395217539999997,0.693272718,-3.258568048477173,-3.878891944885254,-4.213412284851074,-4.2076005935668945,-4.718188762664795 -4425,4425,I256Y,0.075536046,-0.04869162,-0.048438367999999996,-1.681059859,-2.204346671,-0.039112489,0.063124083,0.08794800900000001,-0.06038807400000001,-0.042844433,-0.054538807,-0.074369395,-0.022507341,-1.080602833,-2.281516884,-2.216576869,-2.192116473,2.124409129,1.4019804530000002,-7.661777954,-5.80120108,-5.262743782,-9.73363813,-7.3398887329999996,-10.17141805,-5.625650022,-1.337598181,-7.13228178024292,-7.796080589294434,-6.2877936363220215,-7.910468101501465,-8.71820068359375 -4426,4426,V257A,-0.062846113,0.009135987,-0.025366832000000002,0.038927332,-1.3430452380000002,-0.080772329,-0.089593884,-0.036098342,-0.021947092,0.06083327400000001,-0.042561300999999996,0.002038745,-0.052772409000000006,0.0513436,0.026511062999999998,-0.994964153,-1.691126322,0.564277681,1.338527944,-2.714186549,-3.4624953769999998,-1.971668983,-1.875369057,-3.9934857860000004,-2.2679135440000002,-2.875520186,-1.41286227,-3.115330457687378,-4.2329206466674805,-2.743356227874756,-5.770295143127441,-4.271878242492676 -4427,4427,V257C,-0.02382735,0.01253483,0.014347871000000002,-0.006045966999999999,-0.455446835,-0.075916292,-0.030958596,-0.016696103,-0.017814177,-0.004335815,0.029405473999999997,-0.015978525,0.044674266,-0.044724393,0.032632458999999996,-0.27995319399999996,-0.630940475,1.6528467230000001,2.193288383,-8.768818382000001,-9.036265372999999,-8.600427231,-7.191651267999999,-9.474199593,-9.541548447,-7.161952692000001,-4.872525793,-6.6103515625,-7.603753089904785,-6.394833564758301,-9.031004905700684,-8.186248779296875 -4428,4428,V257E,-0.041742284,0.01345266,-0.9084242790000001,-1.9841138680000001,-2.441804656,-0.08884540199999999,-0.05954282599999999,-0.023941741000000002,-0.043445341,0.048502275,-0.021596956,-0.37636918700000005,-1.44047937,-2.0923466569999998,-1.8758810780000001,-2.388531883,-2.495077428,1.3774376730000002,0.673649424,-9.501699553,-9.584389465,-8.739932807999999,-8.268553123,-10.51002628,-10.40559608,-8.51471993,-6.90408859,-8.981261253356934,-11.380680084228516,-8.95223617553711,-12.093790054321289,-10.482227325439453 -4429,4429,V257D,-0.082873453,-1.353018439,-2.243443264,-2.512696794,-2.984401943,-0.129990974,-0.099693735,-0.06605317,-0.036376228999999996,-1.025896326,-1.680140552,-2.406646061,-2.080240466,-1.99877189,-3.026621697,-2.595987111,-3.372816775,0.5880825470000001,-0.6391257779999999,-10.71917166,-11.31560867,-9.969042465,-9.304372047000001,-11.23815971,-11.7686754,-9.320356452,-9.424452596,-9.947901725769043,-11.1997709274292,-9.179920196533203,-12.421549797058105,-10.702672958374023 -4430,4430,V257G,-0.044010180999999995,-0.358524952,-1.735548553,-2.342862979,-3.164053131,-0.083181745,-0.06636035400000001,-0.021660007000000002,-0.063625609,-0.051807844000000006,-0.66524206,-1.559547781,-1.911549324,-2.068127559,-2.6175983990000002,-2.489251521,-3.83885474,0.6972807759999999,0.02854432,-9.091801323,-9.664670334,-8.116621559,-7.763987052999999,-9.668850479,-10.24487719,-7.019112354,-4.187521179,-5.783242225646973,-7.3585944175720215,-5.37056303024292,-10.154411315917969,-7.964434623718262 -4431,4431,V257F,-0.004322956,0.030132396000000002,0.040317763,-0.761731632,-2.091013819,-0.155540575,-0.014798673,0.006152761999999999,-0.03512635,0.059587027,0.000677764,0.067734713,0.012900812,-0.179758941,-1.3437043219999998,-1.882889662,-2.299137976,1.1274151140000002,1.325951007,-8.226717221,-10.08991094,-8.058535857999999,-6.417245857,-8.096517044,-8.471376403999999,-5.324322302,-1.944202156,-5.204010009765625,-5.229434967041016,-7.003727912902832,-6.564454078674316,-5.886335372924805 -4432,4432,V257I,-0.008981849,0.057217542999999996,0.044391774,0.077527434,0.058652177,-0.123336658,-0.051078701,0.033115003999999996,-0.06374737400000001,0.041785392000000005,0.072649694,0.050876883,0.037906664,0.026386116,0.128668752,0.010106017,0.10719833599999999,1.217427388,2.698016862,-1.9317574919999998,-1.744709969,-0.834241707,-2.929900665,-2.756873085,-1.393062035,-3.886400098,0.022869919,-3.362363815307617,-3.5178961753845215,-4.639057159423828,-3.7598800659179688,-4.69965934753418 -4433,4433,V257H,-0.08031033900000001,-0.436173308,-1.7425183880000001,-2.085803186,-3.009053329,-0.129793569,-0.069814685,-0.090805993,-0.054598867999999995,-0.12907447800000002,-0.7432721379999999,-1.501706323,-1.9833304530000002,-2.22416592,-1.9474404509999999,-2.6452898830000002,-3.372816775,0.902334284,0.055703275999999996,-11.80556571,-11.92361539,-11.95006438,-10.44299136,-11.56061842,-13.15053901,-9.320356452,-9.424453515,-8.548991203308105,-9.711398124694824,-8.294892311096191,-10.368829727172852,-9.303359985351562 -4434,4434,V257K,-0.086502358,-1.5634696080000001,-2.065668699,-2.232862238,-2.792613017,-0.10159075,-0.051710264000000006,-0.121294452,-0.017542764,-1.4760949380000001,-1.6508442769999998,-1.902602163,-2.228735235,-2.448970501,-2.0167539740000002,-2.569064469,-3.016161565,0.062924703,-0.891421928,-9.652694594,-10.24142681,-9.338001678,-8.076927246,-9.939060051,-10.66805718,-8.052853102,-6.082410643999999,-9.281717300415039,-10.477560043334961,-10.615814208984375,-11.934057235717773,-9.651416778564453 -4435,4435,V257M,-0.08843854599999999,-0.02629171,-0.06921277099999999,-0.21128803899999998,-1.704118253,-0.089092903,-0.080417006,-0.096460085,0.018984900000000002,0.005467643,-0.058051062,-0.030398812,-0.10802673,-0.040551211000000004,-0.382024866,-1.648169194,-1.760067311,0.8025795929999999,1.318570145,-4.270540999,-5.367645096,-4.818829353,-2.060260826,-4.518345139,-4.58762458,-3.576214555,-1.927183307,-3.5963337421417236,-5.2248735427856445,-6.315119743347168,-5.2009782791137695,-5.424724578857422 -4436,4436,V257L,-0.028215561,0.000320649,0.006455306,0.026319666000000002,-0.6817602559999999,-0.097560527,-0.015758036,-0.040673085,0.004828397,0.0355556,-0.034914302,0.002410574,0.010500037,-0.014851498000000001,0.06749083,-0.37987784799999996,-0.9836426629999999,0.75828416,1.49911456,-4.491599248,-4.541692436,-4.5454288410000006,-3.27125058,-4.596743813,-5.502880568999999,-3.5094055639999997,-0.04004435,-2.6997203826904297,-3.842726469039917,-4.431365489959717,-2.425753593444824,-4.508161544799805 -4437,4437,V257N,-0.068721636,-0.058192795,-1.427418495,-2.074132729,-2.696352876,-0.10958702099999999,-0.077363985,-0.060079287,-0.12111191,0.075552175,-0.19193776399999998,-1.118640867,-1.736196122,-1.555864735,-2.592400722,-2.153079957,-3.239625795,3.727471903,2.413897355,-10.86052006,-11.26527186,-10.86047649,-9.106927582,-10.81933268,-12.25059168,-9.320356452,-9.424451693,-8.310386657714844,-9.262336730957031,-7.567171573638916,-10.317525863647461,-8.901421546936035 -4438,4438,V257Q,-0.035185518,-0.462269761,-2.050790248,-2.28315067,-2.905370818,-0.056762927000000005,-0.034089646,-0.03628139,-0.05762683,-0.135361379,-0.789178142,-2.050889082,-2.050691413,-1.81910617,-2.74719517,-2.416321392,-3.3944202430000003,0.70545624,-0.16682196400000002,-10.52989763,-11.07927316,-9.956786301000001,-8.72244664,-11.01993928,-11.87104279,-9.320356452,-9.424452843,-8.084227561950684,-9.99490737915039,-8.077841758728027,-9.734932899475098,-9.050958633422852 -4439,4439,V257P,-0.042546460999999994,-1.8507884019999998,-1.9670615219999998,-2.2676060430000002,-2.898690575,-0.08021822,-0.063755297,-0.021337625,-0.09366510800000001,-1.890874014,-1.81070279,-1.974958559,-1.959164484,-2.307447077,-2.227765009,-2.72857104,-3.0688101089999997,-0.207186864,-1.1233923670000001,-10.26252365,-10.90929496,-10.01629845,-8.924765327000001,-10.44028224,-11.02197726,-9.294577263999999,-9.2852372,-8.374460220336914,-9.419589042663574,-9.909709930419922,-11.743576049804688,-12.448448181152344 -4440,4440,V257S,-0.033437742,0.013148696000000001,-0.08784237199999999,-1.6313238369999998,-2.146463024,-0.125518259,-0.019530225,-0.047345258,-0.031020072000000003,0.047099543,-0.020802151,-0.009979215,-0.165705529,-1.277111134,-1.9855365390000002,-2.0069519209999997,-2.285974126,2.435679438,1.628918756,-8.553231488,-8.782029839,-7.6706351779999995,-7.282049338999999,-9.010026031,-10.02141705,-8.035250224,-6.217817909,-5.330728530883789,-6.931755065917969,-4.552765846252441,-8.8162202835083,-6.28041934967041 -4441,4441,V257R,-0.040648226,-1.69158832,-2.100052307,-2.5129266919999997,-3.1921185160000003,-0.11048057800000001,-0.05641681,-0.024879642,-0.142539584,-1.611560425,-1.771616214,-2.02103431,-2.179070303,-2.727103492,-2.298749892,-3.0232887180000003,-3.360948314,0.02435984,-1.059920302,-10.83918245,-11.79571456,-10.22910677,-8.811691681000001,-10.97670217,-12.38269705,-9.320356452,-9.42445405,-8.937179565429688,-10.208978652954102,-9.318119049072266,-11.576811790466309,-9.185657501220703 -4442,4442,V257T,-0.022687517999999997,0.031765812000000004,-0.003675796,0.033407879,-1.444969154,-0.10287835099999999,-0.045372996,-2.04e-06,-0.018304145,0.04537680400000001,0.018154819,-0.005998705,-0.001352887,0.016524585,0.050291173,-1.2401521,-1.649786208,0.641690298,1.3310518390000001,-5.481109235,-5.969787338,-4.398807648,-4.725731224,-6.2302119220000005,-6.0810080410000005,-5.837710362,-5.132698545,-4.902165412902832,-6.223110198974609,-4.7151947021484375,-7.145786762237549,-5.346663475036621 -4443,4443,V257W,-0.010309486999999999,-0.130065334,-1.3208074779999999,-2.364907408,-3.09805193,-0.077496879,-0.004148059,-0.016470915,-0.054790822,-0.000988975,-0.259141692,-1.209135778,-1.4324791769999998,-2.46871456,-2.261100255,-2.588808527,-3.607295333,0.6928074209999999,0.08391108,-9.099029944,-10.74026165,-9.694339127000001,-6.824430244,-7.136149147,-11.09996955,-6.736472432999999,-4.8482505719999995,-8.449435234069824,-9.276732444763184,-9.521594047546387,-11.850924491882324,-9.606364250183105 -4444,4444,V257Y,-0.033432459,0.026914689,0.004857024000000001,-0.599132978,-2.1445361519999997,-0.1557989,-0.018161972,-0.048702946,0.014009988000000001,0.02936388,0.024465498,0.034009647000000004,-0.024295598999999998,-0.136029831,-1.062236124,-2.168168628,-2.1209036759999997,0.983218865,1.292517849,-9.763068236,-10.91373839,-9.916742836000001,-7.6592910000000005,-9.584347031,-10.74122192,-6.362736685,-3.835443549,-7.147972106933594,-5.360010623931885,-7.697941303253174,-9.061925888061523,-7.087695598602295 -4445,4445,V258A,0.011156456,-0.037557101,-0.012404448,-0.010520429,-0.177366222,0.008301585,0.022968355,-0.000655443,-0.0035249559999999997,-0.09853407,0.023419869,-0.09389259400000001,0.069083699,-0.09726330300000001,0.076222446,-0.158922167,-0.195810276,1.254158012,2.057825486,-1.9113005580000002,-1.5560618590000002,-2.143498047,-1.959875732,-3.257089104,-0.63997805,-2.174253353,1.171373905,-1.136521339416504,-2.4336776733398438,0.036084651947021484,-1.5947647094726562,-1.1968317031860352 -4446,4446,V258C,-0.018717432,0.009073619,-0.007921426,-0.011224001,0.008712791999999999,-0.061409171,-0.035445372,-0.001989491,0.041428406,0.002253585,0.015893653,-0.037539324,0.021696472,-0.066794656,0.044346655,-0.005867424,0.023293007,1.197048079,2.424241261,-4.712414476,-5.781599723999999,-5.057299484,-6.202072144,-5.25176429,-1.269336739,-3.8379220239999996,-1.320999984,-5.458621978759766,-6.229397773742676,-4.570104598999023,-6.435750961303711,-5.996096611022949 -4447,4447,V258E,-0.015774562,-0.944824207,-1.60816998,-2.0144356969999997,-2.065323516,0.014432216999999999,-0.01810288,-0.013446244,0.13120469699999998,-0.7142131359999999,-1.175435278,-2.067992024,-1.148347935,-2.145255082,-1.8836163119999998,-2.193191676,-1.9374553559999999,0.325773789,-0.549919549,-9.812441168,-10.94028965,-9.141573326,-10.40591979,-10.52433689,-8.050086182000001,-8.869157542,-8.970034247000001,-11.042678833007812,-11.69397258758545,-8.639155387878418,-14.0341157913208,-12.070466995239258 -4448,4448,V258D,-0.068870506,-0.470390938,-1.5694502000000001,-2.5021420709999997,-2.373518919,0.072621793,-0.034412259,-0.10332875300000001,-0.015472941,-0.152416325,-0.78836555,-1.30207523,-1.8368251690000001,-2.282428275,-2.7218558660000003,-2.330364869,-2.4166729680000003,1.28111415,0.173289599,-10.27886536,-11.60921671,-9.857236145,-11.00237828,-10.78362315,-8.141872498,-8.869157542,-8.970034247000001,-11.012601852416992,-11.136999130249023,-7.676981449127197,-14.342857360839844,-12.614748001098633 -4449,4449,V258G,0.023264172000000003,-0.009486249,0.028035025,-0.028698542,-1.458193585,0.021480389,0.054493424000000006,-0.007965081,-0.067281039,-0.072737257,0.05376476,-0.033343177,0.089413227,-0.015739965,-0.041657118,-1.4455297480000002,-1.470857422,0.6401042920000001,1.320111614,-6.36409883,-8.148089622999999,-4.638996719,-7.801269997,-7.068557281,-4.163580528,-4.628691125,-1.652321088,-5.356775283813477,-6.10600471496582,-4.128401279449463,-7.8662943840026855,-5.995135307312012 -4450,4450,V258F,-0.02695794,-0.072463513,-1.0163347740000002,-1.912312187,-2.973794655,0.014139711999999999,-0.012327423,-0.041588456,-0.011507600000000002,-0.11226802300000001,-0.032659002,-0.640933468,-1.39173608,-1.900040114,-1.924584259,-2.646946712,-3.300642598,1.9030552090000001,0.8398958409999999,-8.159495698999999,-8.178966293,-7.291431519,-10.23924332,-8.229853546000001,-6.857983817999999,-7.456535221,-5.28664883,-9.841687202453613,-10.194782257080078,-8.921809196472168,-10.166872024536133,-8.470845222473145 -4451,4451,V258I,0.025468746,0.0059036259999999995,0.046390745,0.057771834,0.08894501,0.011885737,0.027616647,0.023320845,-0.05705482,0.037067969,-0.025260717999999998,-0.045019172,0.137800661,0.011466028,0.104077639,0.026722574,0.15116744599999998,1.122961387,2.648329456,-2.837062004,-3.272535721,-2.635758049,-3.103370132,-2.60539283,-2.568253288,-4.443180197,-2.820512789,-6.2468109130859375,-6.5532379150390625,-6.194399356842041,-6.762667655944824,-6.469037055969238 -4452,4452,V258H,-0.023263238999999998,-1.746735511,-2.124489571,-2.492014558,-2.84051266,0.018897637,-0.0028694429999999997,-0.043657035,-0.055560841,-1.615230115,-1.878240907,-2.64449791,-1.6044812309999998,-2.721760969,-2.262268146,-2.167637572,-3.513387748,-0.178746375,-1.0480456470000001,-10.76859557,-12.46103688,-10.15658785,-12.14659917,-10.82327518,-8.255478775,-8.869157542,-8.970034247000001,-11.963777542114258,-11.80327320098877,-8.939120292663574,-14.355409622192383,-13.801690101623535 -4453,4453,V258K,-0.108847708,-1.749487373,-2.189710801,-2.131267056,-2.454188897,0.09791333,0.035919825,-0.25361524,-0.12450232,-1.9037435530000002,-1.595231193,-1.978768839,-2.400652763,-2.056031897,-2.206502214,-2.103968492,-2.804409302,-0.513134159,-1.157154373,-9.697293892000001,-11.09576365,-8.75182576,-10.46795579,-9.957396942,-8.213527321,-8.869157542,-8.970034247000001,-12.483562469482422,-12.484611511230469,-12.873955726623535,-14.598917007446289,-14.118378639221191 -4454,4454,V258M,0.044475455,-0.018800871,0.063767046,-1.5518667240000001,-1.7785477280000002,-0.027442312000000003,0.085426914,0.003523995,-0.049800065,-0.13028352199999998,0.09268178099999999,-0.080370072,0.207904163,-1.26899906,-1.834734387,-1.9537577519999998,-1.6033377030000002,2.8023166739999996,1.924474037,-7.292954982,-7.653502045,-7.290457862999999,-7.360493422999999,-7.459300461000001,-6.701021118,-8.071640502000001,-6.3590885870000005,-7.48372745513916,-8.561660766601562,-5.879037857055664,-7.8959641456604,-7.305593967437744 -4455,4455,V258L,-0.042224828,-0.016140287,0.0028722920000000002,-0.10385262,-1.794191325,0.034355759,-0.0006673180000000001,-0.083782337,0.0014563179999999998,-0.066058377,0.033777804,-0.075365248,0.081109832,-0.058993647999999996,-0.148711591,-1.567765466,-2.0206171840000002,0.8731266609999999,1.329927128,-5.37998071,-5.845997665,-5.186815826,-6.1187465439999995,-5.438030716,-4.310312798,-6.631345636,-4.442615867,-8.045684814453125,-8.76557731628418,-6.896936893463135,-7.638697147369385,-7.986447334289551 -4456,4456,V258N,0.014440328999999998,0.028436231,-1.484851215,-2.019225758,-1.8571292119999998,-0.009163236,0.055335370999999994,-0.026454712999999998,-0.03533557,-0.073622669,0.130495131,-0.632018159,-2.337684271,-2.071009053,-1.967442463,-2.118945648,-1.595312775,1.7457844319999998,0.746845854,-9.400452722,-10.86129948,-9.209705589,-10.35011768,-9.414715408,-7.166425453,-7.4690535989999995,-6.181368523,-9.566761016845703,-8.18110466003418,-6.866563320159912,-10.892187118530273,-10.950315475463867 -4457,4457,V258Q,-0.02099978,-1.426388455,-1.74957028,-2.230717157,-2.7041539969999997,0.00826016,0.050375669000000005,-0.092375228,0.008256798000000001,-1.035164417,-1.8176124919999999,-1.779196484,-1.719944075,-2.0325508009999997,-2.428883513,-2.3815173919999997,-3.0267906019999997,3.5611344789999997,1.5225461580000001,-9.587688527000001,-10.85359924,-9.264304085,-10.06813582,-9.748970642,-8.003432854,-8.869157542,-8.970034247000001,-11.254130363464355,-12.012038230895996,-9.710345268249512,-13.480395317077637,-12.362499237060547 -4458,4458,V258P,-0.018105437,-1.57710817,-2.189313586,-2.289391174,-3.324957823,0.016651186999999998,-0.009673209,-0.026537665,-0.04318869,-1.6629358369999998,-1.491280502,-2.462866862,-1.91576031,-2.3318539780000003,-2.246928369,-2.856911827,-3.793003819,-0.452402176,-1.070980582,-10.03341904,-10.80267217,-10.13754273,-10.62183828,-10.41294646,-8.192095542999999,-8.869157542,-8.970034247000001,-11.296571731567383,-10.436980247497559,-9.905404090881348,-13.328678131103516,-11.247248649597168 -4459,4459,V258S,-0.037276498,-0.010526519,0.015465571000000001,-0.45423112200000004,-1.671132712,0.030478504,-0.025397057999999997,-0.049155937999999996,0.005072538,-0.041478483,0.020425445,-0.043322384000000005,0.074253525,-0.15995251900000002,-0.748509724,-1.606371651,-1.7358937730000001,1.06534406,1.346040079,-3.355622102,-4.493235024,-3.188994019,-4.722121445,-3.077992966,-1.295767059,-3.1011880260000004,-0.157095319,-3.6744086742401123,-2.2540950775146484,-1.9629454612731934,-4.4481306076049805,-3.8417129516601562 -4460,4460,V258R,-0.041351078,-1.4654872380000001,-2.213527065,-2.188556715,-3.037054817,0.032889579,-0.031125887,-0.051576269,-0.036773783,-1.539075323,-1.391899152,-2.551952703,-1.875101427,-2.328185765,-2.0489276640000003,-2.8532436139999997,-3.22086602,-0.036481562,-0.995451062,-9.985415871,-11.22357582,-10.02437411,-10.35377822,-10.09021977,-8.235131432000001,-8.805311322,-8.514037598,-12.146015167236328,-11.816582679748535,-10.790281295776367,-13.907377243041992,-14.393203735351562 -4461,4461,V258T,-0.047506797999999996,-0.016114093,0.014154373,0.013067529,-1.1459766470000001,0.051724857,0.0058973969999999995,-0.10091099199999999,0.015556037,-0.055058595,0.02283041,-0.053657570999999994,0.081966316,-0.052562690999999995,0.078697749,-0.9138248809999999,-1.3781284130000002,0.792041702,1.379230711,-2.6323029680000003,-3.191543633,-2.712428177,-2.5485476680000003,-2.600726822,-2.108268539,-3.3899248560000004,-0.5984542420000001,-3.6103672981262207,-2.150402069091797,-1.7230124473571777,-3.9546895027160645,-3.6698384284973145 -4462,4462,V258W,-0.029627458,-1.795899454,-1.775713506,-2.027164139,-2.404658216,0.050350679,0.036169487,-0.09542440199999999,-0.09478598699999999,-1.659752058,-1.93204685,-1.813958591,-1.73746842,-2.2891616569999997,-1.7651666209999999,-2.337098252,-2.472218179,0.040061397,-1.032369719,-10.02960909,-10.94091104,-9.656170303,-10.88805606,-10.44906258,-8.213845451000001,-8.869157542,-8.970034247000001,-13.576197624206543,-13.543551445007324,-11.519415855407715,-15.176998138427734,-13.971365928649902 -4463,4463,V258Y,-0.015492551,-0.7179683859999999,-2.153804852,-2.245876105,-2.568797946,0.011824267,0.02570579,-0.056690892,0.050936355999999995,-0.478861916,-0.957074856,-1.943053287,-2.3645564169999997,-2.020316345,-2.471435864,-2.068252939,-3.069342953,4.08046577,2.19523157,-9.03190869,-10.14858277,-8.705362373,-10.49649725,-8.720519714,-7.088581345,-6.236381337999999,-3.445007873,-11.731391906738281,-10.725825309753418,-8.843328475952148,-13.064316749572754,-11.24795150756836 -4464,4464,I259A,0.016237689,-0.025813887999999997,0.035557073,-1.026115602,-2.396194248,-0.032112264,0.005434207,0.02704117,0.011290742,-0.027770568,-0.023857207999999998,-0.011335246,0.082449391,-0.433967039,-1.618264164,-2.050303389,-2.742085107,1.5928464409999998,1.359157264,-7.972255014,-7.383323166,-8.911997299,-7.047999474,-7.844159232999999,-8.673795898,-3.4176449960000004,-0.578165791,-4.138116836547852,-3.5582916736602783,-4.029376029968262,-7.331958770751953,-4.617682933807373 -4465,4465,I259C,-0.006617213,-0.068404834,0.066826207,-0.035567417000000004,-0.834334283,-0.022547674,-0.006054812,-0.007179614,0.034801219,-0.09341334,-0.043396327,0.047171642,0.086480772,-0.004821698,-0.066313135,-0.452707915,-1.2159606509999998,1.383714249,1.8054317569999998,-10.46375344,-9.69413871,-11.56035831,-11.23857656,-9.833451538,-9.992242065,-6.0904621070000005,-3.0226072860000004,-7.254517078399658,-5.981842041015625,-5.8657379150390625,-10.189940452575684,-7.545947074890137 -4466,4466,I259E,-0.019133861000000002,-1.265967529,-2.088537371,-2.019912975,-2.540625964,0.0044718629999999995,-0.023127118999999998,-0.015140603,-0.036222202,-0.9014805920000001,-1.630454465,-2.157458693,-2.019616048,-2.225210477,-1.8146154719999998,-2.8011676660000004,-2.280084261,0.668318405,-0.577704193,-12.51036276,-12.0451253,-13.34469574,-13.00482675,-11.55085026,-12.60631576,-8.61243677,-5.3556558,-11.050541877746582,-10.597478866577148,-9.459821701049805,-15.66099739074707,-12.286742210388184 -4467,4467,I259D,0.040952266,-1.915802737,-2.418448303,-2.703221578,-2.877019385,-0.037897667,0.045847857,0.036056674,-0.132890139,-2.348850319,-1.4827551540000001,-2.099678442,-2.737218163,-2.468460222,-2.937982934,-2.567296156,-3.1867426130000003,-0.28626015899999996,-1.204060364,-14.38683522,-13.67070865,-15.81508936,-14.95836974,-13.13573602,-14.35427232,-10.22716526,-9.272965999,-11.427083969116211,-11.153894424438477,-9.480576515197754,-16.953250885009766,-14.690389633178711 -4468,4468,I259G,-0.017523743999999997,-0.6581561029999999,-1.863252469,-2.206128201,-2.671910904,0.00344842,-0.021381534,-0.013665953,0.019773286,-0.375386435,-0.940925771,-1.9408826430000001,-1.785622295,-2.173444675,-2.238811727,-2.483133975,-2.860687832,1.34474071,-0.030459264,-12.13163427,-11.57221709,-13.18489487,-12.425702000000001,-11.33777472,-12.13758268,-7.175415298,-4.068156467,-6.461625576019287,-6.72965145111084,-7.10798454284668,-12.212925910949707,-8.758087158203125 -4469,4469,I259F,0.003265234,0.00100186,0.057359127,0.005161446,-1.4583354290000001,-0.029165576000000002,0.02166431,-0.015133843000000001,0.082530252,-0.0442261,0.04622982,0.005373421,0.109344833,-0.042723675,0.053046567,-0.8144268109999999,-2.1022440469999997,0.862141721,1.4093352069999998,-7.734231497000001,-6.144914345,-8.051635185,-8.606619965,-8.954379356,-6.913608635,-7.19455713,-2.8159545689999996,-5.7342681884765625,-4.625004768371582,-6.412745475769043,-9.770462989807129,-8.416580200195312 -4470,4470,I259H,0.015779556,-0.823558578,-1.9718392230000001,-2.370234389,-2.845062192,0.019226563999999998,0.011014653000000001,0.020544458999999998,0.018575698,-0.533099373,-1.114017783,-2.0523189090000002,-1.8913595369999998,-2.296161952,-2.444306826,-2.696027882,-2.994096501,1.260323391,-0.176947155,-14.33454303,-13.01536629,-15.57749876,-15.03004639,-13.5592801,-14.49052362,-10.19652198,-9.062989929,-9.451667785644531,-8.505854606628418,-8.397660255432129,-14.557084083557129,-13.361776351928711 -4471,4471,I259K,-0.028800403,-1.547613779,-2.426923178,-2.561181455,-2.584464264,-0.06389963,-0.065511431,0.007910626,-0.078777246,-1.703190943,-1.392036614,-2.232170317,-2.621676039,-2.299922101,-2.8224408089999997,-2.398758035,-2.770170493,-0.19334162800000002,-1.0826168379999999,-13.30298466,-12.62842825,-14.78173351,-13.57881761,-11.75959104,-13.76635291,-10.22716526,-9.272965955,-12.537699699401855,-12.097268104553223,-11.142882347106934,-16.90074920654297,-13.818867683410645 -4472,4472,I259M,0.022019825,-0.039318208,0.090268359,0.04617153400000001,-0.36692139100000004,0.017065703,0.056467599,-0.012427948999999999,0.018168941,-0.05885645,-0.019779966,0.013643172,0.166893546,0.007573936999999999,0.08476913,-0.306105845,-0.427736936,1.090767595,1.724656547,-5.310280156,-4.773584381,-6.425236496,-5.665681708999999,-5.6336680679999995,-4.053230125,-6.308466682000001,-2.913255139,-5.659794807434082,-5.265898704528809,-6.673078536987305,-8.656668663024902,-6.211546897888184 -4473,4473,I259L,-0.0074622759999999995,0.00025969,0.027529956,-0.00523087,-0.088470575,-0.033488206,-0.022345154,0.0074206030000000004,0.045298632,-0.034663887000000004,0.035183267000000004,-0.007804996999999999,0.06286490900000001,-0.000654333,-0.009807406,-0.059557038,-0.117384111,1.2533724529999999,2.3210336590000002,-4.09143688,-2.990283882,-3.860269012,-5.243272858,-4.49118837,-3.87217028,-5.654433568,-1.619550644,-4.502974510192871,-4.145218849182129,-5.152433395385742,-6.920828819274902,-6.538736343383789 -4474,4474,I259N,0.049565474000000005,-0.446270615,-1.96368322,-2.336502125,-2.66081493,0.063155768,0.075020863,0.024110085,0.036559061000000004,-0.291945468,-0.600595761,-1.3981612490000002,-2.52920519,-1.9430342880000002,-2.729969961,-2.342900218,-2.978729641,3.5749364439999995,1.9594710030000002,-13.59589029,-12.92848701,-15.28806849,-13.88114085,-12.54921775,-13.33253734,-10.20928784,-9.184640344,-6.909801483154297,-8.052903175354004,-7.446192741394043,-13.686090469360352,-11.993255615234375 -4475,4475,I259Q,-0.030910939,-0.7653207409999999,-2.0182674819999997,-2.336514152,-2.899387584,-0.047117267000000004,-0.041499923,-0.020321955,0.027822568,-0.466655821,-1.06398566,-2.062581984,-1.973952979,-2.1303337680000003,-2.542694535,-2.530199698,-3.268575469,1.1125292,-0.209410727,-13.34428223,-12.82746543,-14.51832676,-13.91905456,-11.63315151,-13.823412900000001,-10.22716526,-9.272965952,-9.32224178314209,-8.846220970153809,-8.704803466796875,-14.10592269897461,-11.097930908203125 -4476,4476,I259P,-0.012771635,-1.77422703,-2.02491538,-2.4288082380000002,-2.666364125,-0.003627724,-0.012731263,-0.012812006,-0.026470635,-1.9439865859999998,-1.6044674730000001,-2.162176127,-1.8876546330000001,-2.2920758180000003,-2.565540658,-2.7267038539999997,-2.606024395,-0.880638875,-1.125437005,-13.94016473,-13.3734584,-15.22898036,-13.999257,-13.31833646,-13.78079144,-10.16346523,-8.936462429,-12.580931663513184,-11.283357620239258,-9.066492080688477,-17.19053840637207,-12.994383811950684 -4477,4477,I259S,-0.030388726,-0.076420429,-1.3235449540000002,-2.1608514480000003,-2.874239878,-0.014004822,-0.035433681,-0.02534377,-0.0027832829999999997,-0.016915456000000002,-0.135925401,-1.118338709,-1.5287511980000001,-2.109075309,-2.212627587,-2.5089412380000002,-3.2395385169999997,2.1647281830000003,0.80986155,-9.955215167,-9.07216584,-11.04022029,-9.507480316,-9.539356903,-10.61685249,-5.969520612999999,-2.9578401530000002,-5.178361415863037,-4.918898582458496,-5.387167930603027,-10.216428756713867,-7.499853134155273 -4478,4478,I259R,-0.020776963,-1.805524139,-2.1163742130000003,-2.305927346,-2.4954836780000003,-0.028358604,-0.021506404,-0.020047521000000002,-0.043276512,-1.859276862,-1.751771415,-2.212164976,-2.02058345,-2.154978024,-2.456876667,-2.855873949,-2.135093407,-0.42212540600000004,-1.114607254,-13.968493400000002,-13.35059718,-15.03024307,-14.5024239,-12.48565578,-14.47354706,-10.22716526,-9.272965952,-11.35380744934082,-9.862382888793945,-9.145673751831055,-14.318472862243652,-13.361787796020508 -4479,4479,I259T,-0.004504223,-0.027410059,0.023035262,-0.924139011,-1.997076674,-0.072420049,-0.013055454,0.0040470079999999995,0.00425137,-0.066286704,0.011466586,-0.03593069,0.082001213,-0.543672692,-1.3046053290000001,-1.792270946,-2.2018824009999998,1.558161435,1.429467917,-8.359448515,-8.56974353,-8.885516693,-7.953182541,-8.231493842999999,-8.157305969,-6.154932114,-2.617424452,-5.329029560089111,-3.5245256423950195,-5.423079967498779,-8.418832778930664,-6.239544868469238 -4480,4480,I259W,-0.011617458999999998,-0.011031158000000001,-0.110209634,-1.536861215,-2.428120809,0.087064809,0.0086076,-0.031842518,0.036868575,-0.068064452,0.046002136,-0.053706302000000004,-0.166712966,-1.2632213159999999,-1.8105011130000002,-2.2828760040000002,-2.573365614,2.186508487,1.373218162,-13.12530649,-11.96974539,-13.97483553,-14.01323229,-13.08973362,-12.57898563,-10.22716526,-9.272965963999999,-9.289335250854492,-10.313556671142578,-8.66579818725586,-15.380023956298828,-13.760647773742676 -4481,4481,I259V,0.010544808000000001,-0.005507439,0.040323085,-0.010872965,-0.020923763,0.00767212,0.009911523,0.011178093,0.00353074,-0.040082554,0.029067676,-0.004547454,0.08519362300000001,0.006298475,-0.028044405,-0.046852965,0.005005439,1.3001260479999999,2.6362872040000003,-3.188228323,-3.369792336,-3.20571669,-3.080606033,-3.761401352,-2.5236252059999997,-4.012931183,0.821965532,-3.8325600624084473,-2.2970175743103027,-2.9350404739379883,-4.429059982299805,-2.737076759338379 -4482,4482,I259Y,0.020915231,0.00499355,0.058215089000000005,-1.053517242,-2.403888322,0.033069463,0.056403079,-0.014572618,0.040681302,-0.07902754099999999,0.08901464099999999,-0.03327005,0.14970022800000002,-0.374728703,-1.73230578,-2.086348494,-2.721428149,1.682577698,1.3833352509999999,-11.99125661,-10.65569012,-13.02053458,-12.81673318,-12.16834022,-11.29498497,-8.86039809,-5.638871063,-7.823089122772217,-6.559169292449951,-7.863540172576904,-11.942378997802734,-10.85299301147461 -4483,4483,Y260A,-0.07228285599999999,-0.017491337,-0.491232523,-1.71675373,-2.509598383,0.02361869,-0.094517257,-0.050048455,-0.044963468,-0.004654585,-0.030328088,-0.186958185,-0.79550686,-1.4182109840000001,-2.015296475,-2.335708158,-2.6834886069999997,1.2318294440000002,0.78015655,-11.59599843,-10.12865441,-14.36169131,-9.556068932,-10.91927251,-13.014305,-6.66756516,-2.881714221,-9.889907836914062,-9.27003002166748,-11.059857368469238,-12.436728477478027,-12.578500747680664 -4484,4484,Y260C,-0.05966662,-0.055302440999999994,-0.039341381,-1.00987561,-2.041769272,-0.014622301,-0.101314369,-0.01801887,-0.032125486,-0.049684177999999996,-0.060920703,0.009809075,-0.08849183699999999,-0.45868492899999996,-1.561066291,-1.824405017,-2.259133527,1.693213386,1.427454004,-11.7492586,-12.12689021,-14.02378864,-8.786730064,-10.64636112,-13.16252297,-6.780323556,-2.263819062,-9.622685432434082,-8.732698440551758,-10.585433006286621,-10.786885261535645,-11.440457344055176 -4485,4485,Y260E,-0.04437061,-0.940282026,-1.9810435069999999,-2.4187266259999998,-2.560872172,0.0019077220000000002,-0.049135613,-0.039605606,0.032999133,-0.5877135370000001,-1.292850514,-2.067701743,-1.89438527,-2.590238389,-2.247214862,-2.9817657410000002,-2.1399786030000003,0.8872767859999999,-0.389100913,-13.23631614,-12.32415756,-15.15885511,-11.69851585,-12.66832561,-14.33172655,-9.516601846,-7.418804548,-12.29112434387207,-15.914916038513184,-12.843274116516113,-14.859854698181152,-13.527402877807617 -4486,4486,Y260D,-0.12359138800000001,-1.372445532,-1.870817811,-2.46451362,-3.17182605,-0.012991233,-0.165387036,-0.08179574,-0.08519371699999999,-1.10086917,-1.644021894,-1.893625775,-1.8480098459999998,-2.160889916,-2.768137323,-2.728508527,-3.615143573,3.616910363,1.4543220030000001,-14.62173883,-13.48005814,-18.203388600000004,-11.87273505,-14.49698966,-15.05552271,-9.120452536,-6.791117909,-12.677104949951172,-14.563539505004883,-12.143144607543945,-14.367290496826172,-13.898147583007812 -4487,4487,Y260G,-0.048297163,-0.96498148,-2.049906106,-2.228508013,-2.5964371330000002,-0.010718826,-0.090411006,-0.0061833190000000005,-0.00589641,-0.628918938,-1.3010440220000001,-2.08678728,-2.013024932,-2.169991233,-2.287024792,-2.3241576680000002,-2.8687165980000002,1.25664558,-0.24246105899999998,-13.51905942,-11.93668503,-16.35935231,-11.12224606,-12.70877942,-15.46823428,-7.800460091000001,-4.676206214,-11.638923645019531,-12.1421480178833,-12.157154083251953,-14.041145324707031,-13.696672439575195 -4488,4488,Y260F,-0.147395519,-0.033552122000000004,-0.040019108,-0.038130585,-0.06715326099999999,-0.060307735999999994,-0.07492516,-0.21986587800000001,-0.072429585,-0.029393473,-0.03771077,-0.024596476000000003,-0.05544174,0.031946592999999995,-0.108207762,-0.021114571000000002,-0.11319195,1.181133305,2.500025061,-3.668141696,-2.41479084,-6.398801376000001,-3.0037127910000003,-3.5659154510000004,-2.9574880219999997,-3.456446068,-0.030094309,-5.459986209869385,-4.578200340270996,-7.823474407196045,-5.798193454742432,-7.340155124664307 -4489,4489,Y260I,-0.09533029999999999,-0.06347942599999999,-0.11914961199999999,-0.06770156,-0.888012503,-0.019439605,-0.039666817,-0.15099378300000002,-0.05307656,-0.104034819,-0.022924032999999996,-0.168995093,-0.06930413099999999,-0.121503214,-0.013899905,-0.45867290299999997,-1.317352102,2.0136666119999997,2.2750290680000003,-12.99707597,-11.17831162,-18.01060628,-11.05781602,-12.68474937,-12.05389654,-7.3168769629999995,-3.08144686,-9.231857299804688,-9.644128799438477,-12.281529426574707,-11.768559455871582,-12.899139404296875 -4490,4490,Y260H,-0.041080456,-0.18479290399999998,-1.924316066,-2.319041871,-2.685733682,-0.030575232999999997,-0.069174168,-0.012986743,-0.075801374,0.029392027999999997,-0.398977835,-1.692783502,-2.155848629,-2.340258885,-2.297824856,-2.430756241,-2.9407111230000003,0.526761823,-0.0005654459999999999,-8.99707758,-8.240213318,-10.02224867,-7.580214317,-9.633378876,-9.509332718,-7.963764771,-5.437550076,-9.121760368347168,-10.805938720703125,-8.170215606689453,-9.768954277038574,-9.222818374633789 -4491,4491,Y260K,-0.011171246000000001,-0.788743113,-2.703249595,-2.34540041,-2.964667211,-0.141860836,-0.038013281,0.015670788999999997,-0.057196512000000005,-0.48650676299999995,-1.090979463,-2.499371456,-2.9071277330000003,-2.5447868469999997,-2.146013973,-2.6352842030000003,-3.294050218,0.436570016,-0.483639125,-13.38885349,-12.64384152,-16.34126991,-11.46899885,-13.59174181,-12.89841539,-10.00794245,-9.205784858,-13.489391326904297,-15.682829856872559,-14.22795581817627,-15.45053768157959,-13.639602661132812 -4492,4492,Y260M,-0.073449131,0.029482712999999997,-0.004989957,0.023379691,-0.00915987,-0.11302274300000001,-0.049594482999999995,-0.09730377800000001,-0.038776756,0.010271093,0.048694332,-0.02460752,0.014627606000000001,0.02816632,0.018593062,-0.020474113000000002,0.002154373,1.518083569,2.7533743189999997,-9.783943736,-6.988291771,-14.29872241,-8.284512238,-9.152203392,-10.19598887,-4.908856009,-0.6473990820000001,-6.675741195678711,-9.256548881530762,-10.792736053466797,-10.547228813171387,-10.27596664428711 -4493,4493,Y260L,-0.08491440300000001,-0.020775004,-0.031811312,-0.000948022,-0.046084325,-0.07697824,-0.03523412,-0.134594686,-0.015423212,-0.007878761,-0.033671246,-0.02169377,-0.041928852999999995,0.027425487999999998,-0.029321531,-0.016441901000000002,-0.07572674900000001,1.1219573870000001,2.500446185,-9.394937222000001,-6.149372252999999,-13.74204079,-8.5809543,-8.757868309,-9.744450455,-4.559047713,0.155257905,-6.5638747215271,-8.244973182678223,-10.055908203125,-9.527551651000977,-9.731614112854004 -4494,4494,Y260N,-0.05256500099999999,-0.368327012,-1.7676129230000002,-1.9237781000000003,-2.781605528,-0.003444473,-0.05452636,-0.050603642000000004,0.040031585,-0.050388432999999996,-0.686265591,-1.4638015180000001,-2.071424327,-1.509216909,-2.338339291,-2.502804252,-3.060406804,3.405671808,1.921040951,-12.15684767,-11.76765697,-14.97679545,-9.590075667999999,-12.25124696,-12.19846331,-8.659608795,-6.388198237,-8.638108253479004,-10.838617324829102,-9.863263130187988,-11.387173652648926,-11.832414627075195 -4495,4495,Y260Q,-0.061500257999999995,-0.022123325,-0.687588545,-1.979071578,-2.9505208960000004,-0.036250582999999996,-0.07083524599999999,-0.05216526900000001,-0.058462377999999995,-0.027300959,-0.01694569,-0.325207542,-1.0499695470000001,-1.695134025,-2.26300913,-2.438843895,-3.462197897,1.528841336,0.78963823,-11.142638,-10.66141721,-13.7358939,-9.652681763,-11.50468201,-10.15851513,-6.252297467999999,-4.236982022,-9.932319641113281,-13.894068717956543,-11.427936553955078,-12.764851570129395,-11.379631996154785 -4496,4496,Y260P,-0.058138034000000005,-1.562253741,-2.064005811,-2.484307877,-2.5155290480000003,0.009588218,-0.08367318900000001,-0.032602879,-0.110849944,-1.652062961,-1.47244452,-1.98888761,-2.139124011,-2.636362993,-2.332252761,-2.550769089,-2.480289006,-0.043995955,-1.069313228,-14.82202447,-13.40235117,-17.79424993,-12.69574359,-14.48232264,-15.73545503,-10.00794245,-9.205784818,-16.764610290527344,-17.81192970275879,-14.081459045410156,-18.720905303955078,-15.48814868927002 -4497,4497,Y260S,-0.061731257000000005,-0.029667082,-0.371459414,-1.789700372,-2.7245762819999997,-0.073910141,-0.094557031,-0.028905483,-0.027906979,-0.001603376,-0.057730787,-0.10856678300000001,-0.634352045,-1.436871945,-2.142528799,-2.216579467,-3.232573097,1.36834592,0.816332658,-9.693370224,-9.086387611000001,-12.71046552,-6.902050911,-8.637379272,-11.130567800000001,-6.70220929,-4.858032158,-8.357211112976074,-10.046143531799316,-8.795845031738281,-11.367541313171387,-11.505589485168457 -4498,4498,Y260R,-0.07792806599999999,-1.616122091,-2.223777567,-2.225838455,-2.746634556,-0.058082475999999994,-0.131275459,-0.024580672,-0.11328506699999999,-1.601567206,-1.630676976,-2.372047416,-2.075507717,-2.241371549,-2.21030536,-2.456807641,-3.03646147,-0.032484545,-1.047981936,-14.48581558,-14.71467525,-18.30357701,-12.74436176,-14.30432349,-12.36214037,-9.809122211,-8.256829066,-13.215864181518555,-14.341127395629883,-13.054023742675781,-15.215490341186523,-12.142959594726562 -4499,4499,Y260T,-0.103093154,-0.054476467,-0.079361717,-1.051979135,-2.274308919,-0.014279584,-0.118310001,-0.08787630699999999,-0.040105668,-0.019997939,-0.088954995,-0.08071724200000001,-0.078006192,-0.5654653279999999,-1.538492942,-1.79514186,-2.753475977,1.8864402359999999,1.501916786,-10.92885226,-9.803135475,-13.51393238,-8.700574722,-10.40580414,-12.22081456,-6.795837818,-3.607504258,-9.510849952697754,-9.806955337524414,-10.952143669128418,-11.57923698425293,-11.756144523620605 -4500,4500,Y260W,-0.038686043999999996,-0.047330685,-1.102839299,-2.14392802,-3.221421795,-0.059147698,-0.082652529,0.0052804409999999994,-0.07375445900000001,-0.048892185,-0.045769184000000004,-0.728596586,-1.477082011,-1.96200246,-2.325853579,-3.1316810619999997,-3.311162527,1.921668819,0.813342199,-10.09501888,-10.22924792,-12.01098456,-9.139470497000001,-9.063654968,-10.03173646,-8.290860154,-6.126662747,-8.515850067138672,-11.16719913482666,-6.731935501098633,-11.73373031616211,-13.02272891998291 -4501,4501,Y260V,-0.122977346,-0.023628067000000003,-0.031510371,-0.02200698,-1.413474729,-0.031581751,-0.059360219000000006,-0.18659447199999998,-0.027461958999999998,-0.0015729079999999998,-0.045683225,-0.016797357,-0.046223385,0.000822253,-0.044836213,-1.034640295,-1.7923091619999998,0.821454006,1.368770616,-13.04895522,-11.49013168,-17.54958967,-10.59640195,-11.73966512,-13.86898766,-7.0313483429999994,-3.8355486880000003,-9.67261028289795,-9.2307710647583,-11.928142547607422,-11.779704093933105,-12.599665641784668 -4502,4502,T261A,-0.014285978999999999,0.031585043,0.00022499,-0.007997066,-0.117114405,0.042901361,-0.035555301,0.006983343,0.054626727,0.014025895,0.049144191,0.066962824,-0.066512844,0.020116008,-0.036110139,-0.092204458,-0.142024352,1.133841839,2.235642028,-3.5120261060000004,-3.3514127730000003,-4.5638608860000005,-3.806197578,-2.26745713,-3.571202164,-4.494667495,-2.403969423,-4.695941925048828,-8.003847122192383,-3.414945602416992,-4.448678016662598,-5.633114337921143 -4503,4503,T261C,0.003694396,-0.031294852000000005,-0.030040808999999998,0.00424798,-0.065010882,0.02695247,0.023088591000000002,-0.0156998,-0.015594038000000001,-0.046863387,-0.015726317,0.038421176,-0.098502793,0.033509274,-0.025013314,-0.031333519,-0.09868824400000001,1.350152086,2.616512074,-4.512133832,-3.2034690930000003,-5.500652733,-8.244894646,-0.421696716,-5.189955971,-3.790493301,-2.872153303,-6.662242889404297,-7.011977195739746,-4.499578952789307,-5.669792175292969,-5.597137928009033 -4504,4504,T261E,0.039859412000000004,-0.059440648,-0.081492935,-0.157045469,-1.447797775,-0.191770437,0.07504148,0.004677344,-0.023980377,-0.060003654000000003,-0.058877640999999994,0.008482969,-0.171468838,-0.034370996,-0.279719942,-1.343887859,-1.5517076909999998,0.637290785,1.325152765,-7.557720436,-6.3646075589999995,-8.587375900000001,-8.518826386,-6.366083099,-7.951709236,-5.354834656,-4.721116578999999,-6.083131313323975,-11.368148803710938,-5.908290863037109,-9.4034423828125,-10.381772994995117 -4505,4505,T261D,0.030741786,-0.155714523,-0.5066787389999999,-0.706035484,-1.133929996,0.01022771,0.023531156,0.037952415,0.370471304,0.232614481,-0.544043526,-0.180972252,-0.832385225,-0.287808527,-1.124262441,-0.6784852029999999,-1.5893747880000002,2.262126935,2.292978863,-9.533139777,-9.107868423,-11.84589209,-9.880145271,-7.193527199,-9.6382659,-6.443163018,-6.324624817999999,-8.43345832824707,-10.16197395324707,-5.860539436340332,-9.818194389343262,-9.998218536376953 -4506,4506,T261G,-0.036664943,-0.001234837,-0.017182418999999997,-1.322676215,-2.325524065,-0.051397463,-0.025384518,-0.047945367,0.012822198,-0.012291503999999998,0.009821831,0.026859672,-0.06122451,-0.8843124370000001,-1.761039993,-2.07271327,-2.578334859,2.067978617,1.46461415,-7.12929641,-6.566768791,-7.364131767000001,-8.571052032,-5.342426453,-7.802103004,-5.6481758939999995,-4.187743361,-8.700468063354492,-9.970165252685547,-6.288161277770996,-8.088446617126465,-9.00609016418457 -4507,4507,T261F,-0.044521289000000006,-0.012889473,-0.051048655,-0.037952887000000005,-0.069969718,-0.006021858000000001,-0.020356021000000002,-0.068686557,-0.011310625,-0.003476786,-0.02230216,0.004186028,-0.10628333699999999,0.018393444,-0.094299218,-0.023409322000000003,-0.116530114,1.181659282,2.445348648,-5.117860339,-5.613324997,-6.018670532000001,-6.735234833,-1.7859403459999998,-5.436130989,-3.6585157660000003,-2.368530593,-3.9483590126037598,-4.051392555236816,-1.8032400608062744,-5.873165130615234,-2.3430233001708984 -4508,4508,T261I,-0.030540215,2.34e-05,-0.038620157,0.008888233,0.027491917,0.088767939,-0.035476038,-0.025604391,0.051343085999999996,0.012744297,-0.012697487,-0.003989522,-0.073250791,0.026188633,-0.008412167,0.044644207000000005,0.010339626999999999,1.090621435,2.630263657,3.277041536,3.323406761,2.516452042,3.2474024810000004,5.873855392,1.424091003,-0.522038907,-1.292592916,-1.5928525924682617,-3.779737710952759,0.24431777000427246,-4.566429615020752,-2.245223045349121 -4509,4509,T261H,-0.001769028,-0.003583015,-0.020217945,0.037207396000000004,-1.388134769,-0.063739223,0.015760414,-0.01929847,-0.03819257,0.008898598,-0.016064628,0.0029705440000000003,-0.043406433,0.09050342,-0.016088629,-1.347961745,-1.4283077919999998,0.784739269,1.3369278470000001,-6.864714277999999,-4.479100113,-8.002787735,-9.924378792,-5.260623466,-6.656681282,-4.443497762,-4.420776551,-5.643031120300293,-6.991048336029053,-5.46371603012085,-7.938809871673584,-5.205682277679443 -4510,4510,T261K,-0.044051031,-0.032426187999999995,-0.113977936,-1.084118095,-1.583893884,-0.076007511,-0.0023738739999999998,-0.08572818800000001,0.101040294,-0.008761513,-0.056090862000000005,0.011139213,-0.239095085,-0.836648627,-1.331587563,-1.085852128,-2.081935639,3.686238482,3.283722507,-7.720299409,-7.072134308,-8.917007988,-8.709692733999999,-5.799580917,-8.1030811,-7.646808044,-9.277853798999999,-8.433158874511719,-13.125060081481934,-8.276168823242188,-9.901870727539062,-9.480379104614258 -4511,4511,T261M,-0.020998582999999998,0.053144428,-0.022079583,0.010826222,0.039460117,-0.054975711,-0.010452412,-0.031544754,-0.040520272,0.072413817,0.033875037999999996,0.02842619,-0.07258535599999999,0.053755015,-0.032102571,0.06902793,0.009892303,1.151352105,2.927102096,2.532973883,2.722586792,1.146748825,2.858327263,5.294254417,0.642952118,-1.094487602,-3.198127944,-1.9246582984924316,-3.141711711883545,-1.201000452041626,-4.634949684143066,-2.3858449459075928 -4512,4512,T261L,-0.031351776,-0.006616761,-0.044324127000000005,0.0028878959999999996,0.020071381,0.16211304599999998,-0.036644419,-0.026059132999999998,-0.015112181,-0.002413708,-0.010819813999999999,0.007891318000000001,-0.09653957099999999,0.019570545,-0.013794754,0.028627251,0.01151551,1.120269569,2.7206370910000004,3.645090091,3.570366051,2.10985791,4.08937088,6.755315979,1.700539635,0.046950566,-0.951933762,0.5124249458312988,-1.0333189964294434,1.1487758159637451,-2.1793246269226074,-0.07756710052490234 -4513,4513,T261N,-0.036233932999999996,0.001601363,-0.038955767,-1.349785869,-2.063688368,-0.051540832,-0.0051095179999999995,-0.067358347,0.029436146,0.014159295,-0.01095657,-0.010365114,-0.06754642,-0.929337138,-1.7702345990000001,-1.67018104,-2.457195696,2.6554563190000002,2.012494189,-7.168128453,-6.639373268,-8.313595024,-8.935227074,-5.513446579,-6.43900032,-5.2021824930000005,-4.41433678,-6.532402515411377,-7.997665882110596,-5.691531658172607,-7.100513935089111,-7.158997058868408 -4514,4514,T261Q,-0.026865226000000002,-0.00275608,-0.021137747999999998,0.006407391,-0.734585906,-0.014863336999999999,0.009702111999999999,-0.063432564,0.014772212,-0.031777404,0.026265245,0.021705917,-0.063981412,0.025387375,-0.012572594,-0.5103628729999999,-0.9588089390000001,1.1699289940000002,1.6263789419999999,-4.767972841000001,-4.741293152,-5.357062706000001,-5.36631485,-2.7241427380000003,-5.651050757999999,-5.142377456,-5.646783214,-5.183516502380371,-8.716676712036133,-5.605617523193359,-5.8435468673706055,-7.5670552253723145 -4515,4515,T261P,-0.051729660999999996,-1.209048012,-1.4783914740000001,-1.705794403,-2.009491872,-0.071243059,-0.025604356,-0.077854965,-0.052075845,-1.0654965779999999,-1.352599445,-1.275320625,-1.6814623219999998,-1.4214102,-1.990178606,-1.537679359,-2.481304385,4.366353343,2.898416335,-8.584564052000001,-8.154872025,-9.921804855,-9.396705505,-6.840224373,-8.609213501000001,-7.646808044,-9.277853798999999,-9.68606948852539,-11.192890167236328,-6.598477363586426,-11.08860969543457,-10.184335708618164 -4516,4516,T261S,-0.04153625,0.005249399,-0.027775817999999997,-0.012569236000000001,-0.152342955,-0.039757827,-0.055492547999999996,-0.027579951000000002,0.01807994,0.007255633,0.003243164,0.042052023,-0.09760365900000001,0.030696151,-0.055834623,-0.107695851,-0.196990058,1.43893518,2.435965157,-3.696815382,-2.004771515,-4.224057846,-5.828063255,-2.619714195,-3.8074701,-3.299103984,-0.549150281,-5.17400598526001,-5.986490726470947,-3.9387879371643066,-4.144941329956055,-5.474075794219971 -4517,4517,T261R,-0.047435105,-0.0053314619999999995,-0.22735906399999997,-1.6601801669999998,-2.221617153,-0.061305822,-0.029643976000000002,-0.06522623400000001,0.038482868999999996,-0.002044636,-0.008618288,-0.037572142,-0.417145986,-1.340992737,-1.979367597,-1.772584238,-2.670650068,3.3144831060000004,2.457911933,-6.857941971,-8.071361259,-7.635661728,-7.1355267179999995,-5.219129875,-6.228030273,-6.381694369,-6.779492967,-8.130712509155273,-11.60837459564209,-8.216893196105957,-10.555072784423828,-8.133594512939453 -4518,4518,T261W,-0.03827179,-0.021851206,-0.05495697,-1.328809776,-2.401692131,-0.06723920900000001,-0.0037301590000000003,-0.07281342,0.042824127000000003,-0.04573751,0.002035099,-0.036264641,-0.073649298,-0.964409084,-1.6932104669999999,-2.131942539,-2.671441722,2.083651164,1.438073243,-7.323701797000001,-5.9325257570000005,-9.593874298,-8.626766487000001,-5.153449615,-7.31189283,-5.176521596000001,-5.092067627,-8.710132598876953,-8.271482467651367,-5.758954048156738,-9.026009559631348,-8.684514999389648 -4519,4519,T261V,0.004266720999999999,0.013900202,0.020052301,0.032847247,0.010115662,0.091204147,-0.005128185,0.013661626000000001,0.025662384,0.011315133,0.016485271,0.071308852,-0.03120425,0.052959044000000004,0.012735449,0.014852278,0.005379046,1.114724013,2.619711616,1.951414241,1.8126194080000002,1.7852749940000001,1.5795284580000002,4.105285858,0.47436248799999997,-1.656496313,-0.631351952,-1.7636730670928955,-5.022197723388672,-0.5195491313934326,-4.054932594299316,-3.2675938606262207 -4520,4520,T261Y,-0.054803606,0.016493944,0.018235118999999998,-0.371292389,-1.629958204,-0.07076115200000001,-0.001800183,-0.10780702800000001,0.048366282000000003,0.07044913400000001,-0.037461247,0.087809976,-0.051339739,0.018195138,-0.760779915,-1.337376576,-1.922539831,0.561859367,1.320689651,-6.528076045,-4.239351334,-9.035394753,-9.587568747999999,-3.151636696,-6.6264286960000005,-3.424101368,-2.205381852,-6.113757610321045,-4.839475631713867,-3.17154598236084,-7.257388114929199,-2.6929047107696533 -4521,4521,T262A,0.011848743,-0.024133379,0.012453365,-0.027588368,-0.18460336300000002,0.019847643,0.014933162,0.008764323000000001,-0.006035782,-0.004324182,-0.043942575,-0.037257789,0.062164519,-0.025105443999999998,-0.030071291,-0.165429824,-0.20377690199999998,1.2838167440000001,2.066464124,-4.149901099,-3.927634903,-4.961742622,-4.079368713,-4.302227959,-3.4785312960000003,-4.667009366,-1.24072319,-7.626895904541016,-6.848687171936035,-5.900045394897461,-7.375186920166016,-7.606013298034668 -4522,4522,T262C,-0.020163147,-0.023859035,0.004085288,-0.049625657999999996,-0.499777363,-0.012773316000000002,-0.008002867,-0.032323426,-0.041023277000000004,0.000956118,-0.048674187,-0.022639137,0.030809713,-0.018919703,-0.080331613,-0.314724307,-0.684830418,1.3507753130000002,1.910469959,-9.45830834,-7.8044279020000005,-10.63278175,-8.962347694,-10.002203699999999,-9.889780655,-8.084541927,-4.201648578,-10.696929931640625,-11.715850830078125,-10.324973106384277,-9.649028778076172,-12.025253295898438 -4523,4523,T262E,0.00072749,-0.009113868,-0.005898191999999999,-0.032555413,-0.34293720899999997,0.015745521000000002,0.006154741,-0.004699762,0.074728013,0.010249704,-0.028477439,-0.099266564,0.087470181,-0.035297089,-0.029813737000000003,-0.319983559,-0.365890858,2.052106022,2.500303776,-9.382194424,-9.321837936,-10.24132143,-9.057890686,-8.871168465,-9.418753601,-4.865470376,-1.038974493,-9.750358581542969,-6.8920135498046875,-7.804978847503662,-10.857146263122559,-10.385773658752441 -4524,4524,T262D,0.016751967,-0.007382977,-0.004817269,-0.029182469,-1.492670549,-0.036967075,0.034264988999999996,-0.0007610560000000001,-0.043957962,-0.0016488429999999999,-0.013117111,-0.047268925,0.037634388,0.01860307,-0.076968008,-1.4653467580000001,-1.51999434,0.458796644,1.310537506,-8.83371104,-7.595291199,-10.97392264,-8.188586166,-8.172025635,-9.238729561,-6.502219107,-1.264493919,-9.983614921569824,-6.349681377410889,-7.2641801834106445,-11.096431732177734,-11.03668212890625 -4525,4525,T262G,-0.007282321,-0.014294871,-0.009217002,-0.128957456,-1.73144799,-0.008249249,0.001195197,-0.015759838999999998,-0.031805125,-0.006128565999999999,-0.022461176,-0.05013849099999999,0.031704487,-0.015356322,-0.242558589,-1.642255695,-1.820640284,0.444685786,1.304532869,-6.792878932000001,-8.333815956,-5.812388695,-7.99049337,-6.138011841,-5.689684799,-5.868810379,-2.2205034340000003,-9.445940971374512,-7.693279266357422,-7.856802940368652,-8.316551208496094,-9.670448303222656 -4526,4526,T262F,0.022710498,-0.01090472,0.022961332,-0.014943008999999998,-0.92448673,0.005847722,0.043344693,0.002076302,-0.022259482,-0.002937333,-0.018872106,-0.042359425,0.08828208900000001,-0.040471131,0.010585113,-0.6894348509999999,-1.1595386079999999,0.97504803,1.47039466,-10.66048442,-9.713035187000001,-12.0591229,-10.3340136,-10.50092654,-10.69532387,-7.54727813,-4.48376697,-11.012730598449707,-10.410672187805176,-9.277303695678711,-11.986542701721191,-10.47792911529541 -4527,4527,T262I,-0.017412538,-0.025216039,-0.046369305,-0.093185835,-0.328180078,-0.001555474,0.010087077,-0.044912152000000004,0.100168479,-0.014565015,-0.035867063,-0.145687012,0.052948403,-0.114529912,-0.07184175799999999,-0.346146936,-0.310213219,1.482670916,1.9343737490000001,-8.338454524,-7.365131081,-10.06267982,-7.511862595,-7.76326767,-8.989331451,-7.920299201000001,-4.088838486,-9.964302062988281,-7.607827186584473,-9.066009521484375,-9.777350425720215,-9.368313789367676 -4528,4528,T262H,0.014487176000000001,-0.016890748,0.0017189879999999999,-0.041867014,-0.056949167,-0.032519822000000004,0.01460496,0.014369392,-0.006481471999999999,-0.018671361,-0.015110133999999999,-0.054226783,0.057664757999999997,-0.041690111,-0.042043917,-0.06610042599999999,-0.047797907,1.417506744,2.441899588,-7.848566275,-6.100214401000001,-8.972610481,-7.381778137,-7.55733622,-9.230892136,-6.591762974,-2.413720546,-9.190027236938477,-10.769185066223145,-8.689927101135254,-10.063974380493164,-10.285443305969238 -4529,4529,T262K,0.007479156999999999,-0.046787775999999996,-0.0059101119999999995,-0.006335176,-0.288236162,0.063129212,0.00734704,0.007611274,0.034006173,-0.027156836,-0.066418715,-0.084971802,0.07315157900000001,0.007926739,-0.02059709,-0.32429408600000004,-0.252178238,1.461701836,1.98750196,-7.050550815,-6.584538322,-8.319453995,-6.808058456,-5.633666267000001,-7.907037033,-5.039956949,-0.631447024,-9.214669227600098,-10.688767433166504,-9.243640899658203,-10.480490684509277,-9.754413604736328 -4530,4530,T262M,-0.0011178639999999999,-0.01789127,0.0069682319999999996,-0.014061376,-0.303880306,0.062160104,0.0061240190000000005,-0.008359746999999999,0.10288746300000001,0.010101623,-0.045884162,-0.026005626,0.03994209,0.008258169000000001,-0.036380921000000004,-0.20199746699999999,-0.40576314399999996,1.208418751,1.9610868609999998,-7.150220375,-6.119265091,-8.725239349,-7.257596596,-6.857623413,-6.791377426,-6.920505202,-2.8538905710000004,-9.550524711608887,-9.457802772521973,-9.215641021728516,-10.489371299743652,-9.709200859069824 -4531,4531,T262L,-0.012137823999999998,-0.013693745,-0.001172104,-0.042542135,-1.271330923,0.058934492000000005,0.025744285,-0.050019932999999996,-0.019782714,0.004186877,-0.031574366,-0.041268683,0.038924476,-0.04246222400000001,-0.042622046,-1.038867991,-1.503793855,0.830296741,1.3695451769999998,-9.165628055,-7.42555542,-11.23355715,-8.785360374,-8.477951256,-9.905716072,-7.410045332999999,-3.994255027,-8.698493957519531,-9.419635772705078,-8.886007308959961,-10.509746551513672,-9.597725868225098 -4532,4532,T262N,-0.009044304,-0.027645316,-0.036746265,-0.07247181700000001,-0.25209262600000004,0.026403523999999998,-0.019764052,0.001675445,0.043912555,-0.038892363,-0.016398268,-0.08163875,0.008146221,-0.030784892,-0.114158742,-0.199402443,-0.304782809,1.661032361,2.346463409,-7.177688963,-6.340127289,-6.210756821,-6.88868119,-7.839890662999999,-8.608988853,-5.8279781879999994,-1.7044311840000002,-7.748495101928711,-6.787319183349609,-7.362741470336914,-8.527202606201172,-8.848488807678223 -4533,4533,T262Q,0.01593764,-0.012038894,-0.022007389,-0.019957494,-0.12715858300000002,-0.003303514,0.052434839000000004,-0.020559558999999998,0.06829655,-0.000535552,-0.023542235,-0.082787172,0.038772395,-0.003830992,-0.036083995,-0.164170066,-0.09014709900000001,1.385678329,2.187890627,-8.625826591000001,-8.421038246,-8.844362381,-8.861117263999999,-7.961960228,-9.040654839,-6.700774634,-1.788018251,-9.89796257019043,-8.942429542541504,-8.748103141784668,-9.017868041992188,-9.40908145904541 -4534,4534,T262P,-0.024020357000000003,-0.297829203,-1.51467981,-2.012471149,-2.535717236,0.035346496,0.013757778,-0.061798491,-0.031593282,-0.083797022,-0.511861383,-1.4391423509999999,-1.590217269,-1.947821214,-2.077121084,-2.375723948,-2.695710524,3.650370446,2.066779367,-11.35265139,-10.79673875,-12.04243652,-10.6154052,-11.85809808,-11.45057841,-9.766513152,-6.437760534,-11.98497486114502,-12.77855396270752,-9.108438491821289,-11.589109420776367,-11.7318754196167 -4535,4535,T262S,0.031549021000000003,-0.011046225,0.0061523540000000005,-0.026530357999999997,-0.076728028,4.9e-05,0.049801628,0.013296414,-0.027476615,0.0027804229999999997,-0.024872872999999997,-0.046428747,0.058733455,-0.041845278,-0.011215437,-0.087966134,-0.065489922,1.4287967990000001,2.386921926,-4.853970601,-3.736562202,-3.9302580639999998,-4.7847204439999995,-5.905135735,-5.913176559,-4.072834797,-0.7119671129999999,-6.0468268394470215,-4.9744553565979,-5.087604522705078,-5.635085105895996,-6.272731304168701 -4536,4536,T262R,-0.002055447,-0.021307677,0.00906787,-0.039143154,-0.770570643,0.04611018099999999,0.018395276000000002,-0.022506169,-0.040772123,-0.006245214,-0.03637014,-0.050130398,0.068266138,-0.0311096,-0.047176708,-0.5579376389999999,-0.9832036470000001,1.014552155,1.5273885459999998,-6.536943355,-5.274847351,-7.103636848,-7.554369949,-5.930428307000001,-6.821434319,-4.450871755,-0.554171596,-9.573667526245117,-10.650879859924316,-9.378658294677734,-10.445643424987793,-10.097025871276855 -4537,4537,T262W,-0.002091769,-0.022006907000000003,0.018885843,-0.026839077000000003,-0.543352313,0.052812230999999994,0.023180218,-0.027363756,-0.011496702,-0.010330231,-0.033683582000000004,-0.033749678,0.071521364,-0.032146571,-0.021531582,-0.365837275,-0.720867351,1.8295330580000002,2.244154105,-10.23424948,-9.047029854,-11.23502734,-9.491521812,-10.202839599999999,-11.1948288,-6.712109229,-3.7282675419999998,-13.56508731842041,-12.972373962402344,-10.677681922912598,-14.102497100830078,-12.966299057006836 -4538,4538,T262V,0.004094788,-0.014804794,0.002196313,-0.040168926,-0.078381564,-0.021448175,-0.008229329,0.016418905,0.037269626,0.007274023,-0.03688361,-0.04080321,0.045195835999999996,-0.024370972999999997,-0.055966878,-0.060957609,-0.095805518,1.237246678,2.34953621,-6.610072385,-5.686063721,-8.810518425,-5.867086395,-6.030935989,-6.655757392999999,-6.452765512999999,-3.0905689510000003,-9.634840965270996,-7.782466411590576,-7.982527732849121,-9.728636741638184,-8.720085144042969 -4539,4539,T262Y,0.04205206400000001,0.005950653,0.005186751,-0.029583539,-0.18513876399999998,-0.045929654,0.0280406,0.056063528,-0.046632902999999996,-0.005201194,0.0171025,-0.057595945999999995,0.067969448,-0.041006593,-0.018160485,-0.158060254,-0.212217273,1.466024791,2.187192313,-10.03465033,-8.536677582000001,-11.273066,-9.232341331,-10.070469699999999,-11.06069702,-7.125847021,-3.556608807,-10.866588592529297,-10.601634979248047,-8.802092552185059,-11.782608032226562,-11.0872220993042 -4540,4540,G263A,-0.028484372999999997,-0.009941599,-0.03760421,-0.020299826,-0.974024595,0.167584776,-0.043938427,-0.013030318,0.043044517000000004,-0.0032855109999999996,-0.016597687,-0.016808879,-0.058399541,-0.014968249,-0.025631402999999997,-0.789211158,-1.158838032,0.7361847340000001,1.3864334669999998,-4.209983147,-4.137628609,-5.080710732,-2.736112312,-3.489566475,-5.605897606,-3.790887984,-1.127860543,-3.733902931213379,-5.266083240509033,-3.9378345012664795,-3.8007402420043945,-5.870561599731445 -4541,4541,G263C,-0.09720748,-0.007663335,-0.040404932000000005,0.000712993,-1.002343849,0.178624248,-0.10690145699999999,-0.087513503,0.06847394,0.044535054000000004,-0.059861723,0.005176643,-0.08598650699999999,0.03210325,-0.030677265,-0.76794235,-1.236745348,0.455173506,1.352391266,-8.766781047,-8.119428711,-9.239565605,-8.50408535,-8.4178078,-9.553017769,-6.22969773,-4.825425468,-8.032281875610352,-10.066046714782715,-9.234394073486328,-8.150484085083008,-11.495134353637695 -4542,4542,G263E,-0.049265962,0.0028789420000000002,-0.033242707999999996,0.007960835999999999,-0.511025386,-0.017357618999999998,-0.035118434,-0.063413489,0.091604503,-0.002302086,0.008059969,-0.003931559,-0.062553857,0.033056363,-0.017134691,-0.36989251799999995,-0.652158253,1.763906751,2.207113698,0.39773747600000003,0.318015404,0.22959050000000003,0.168523697,0.7928812479999999,0.47967652899999996,-1.425394296,-0.876365216,-0.15498018264770508,-3.2466979026794434,-3.0091371536254883,-1.9749199151992798,-4.359766483306885 -4543,4543,G263D,-0.020420396,-0.007605785,-0.022483863,-0.017287217,-0.225119598,-0.010112809,-0.038503139,-0.002337652,0.014340176000000001,0.008820762,-0.024032332000000003,-0.01114213,-0.033825595,0.003138529,-0.037712962999999995,-0.174608906,-0.27563029,1.31493548,2.079034833,-0.666998534,-0.8245933000000001,-0.278123787,-1.3711585309999998,-0.12049439199999999,-0.7406226579999999,-1.961873061,-0.289909593,-2.2544078826904297,-3.4815516471862793,-3.25626802444458,-3.3607635498046875,-6.277557373046875 -4544,4544,G263F,-0.034010893,0.012810676000000002,-0.03338027,-0.310949111,-1.960090392,0.038793158,-0.037540463999999996,-0.030481321000000002,0.021625596,0.035135496,-0.009514144,-0.02190677,-0.04485377,-0.037441296,-0.584456926,-1.895854692,-2.024326091,0.780512767,1.304420302,-10.43263229,-8.653844391,-10.09994276,-9.478297264,-12.10291817,-11.82815884,-5.882785527,-4.213475428,-7.3316779136657715,-9.372371673583984,-6.848249435424805,-7.618886947631836,-9.143684387207031 -4545,4545,G263I,-0.084415327,-0.015492916,-0.09630143199999999,-1.4048722390000001,-2.225456764,0.159107511,-0.121182521,-0.047648132999999995,0.11045258599999999,-0.028735704,-0.002250127,-0.021461757999999997,-0.17114110600000002,-0.852437983,-1.957306495,-1.997621927,-2.453291601,2.058817333,1.485659766,-8.503029451,-9.624964592000001,-10.63015932,-4.759716903999999,-8.813308188999999,-8.686998252999999,-5.0304128530000005,-3.764095653,-6.946465969085693,-9.846996307373047,-6.754925727844238,-7.311651229858398,-9.602214813232422 -4546,4546,G263H,-0.0036760490000000002,0.002963259,-0.05831865,-0.020381756,-1.588938653,-0.032093197000000004,0.002237209,-0.009589307,0.057746236,-0.006766543000000001,0.01269306,-0.071361794,-0.045275505,0.021275907,-0.062039418,-1.46579636,-1.712080945,0.675564488,1.321332518,-5.087114111,-3.4460756839999998,-4.3785207669999995,-7.17128569,-5.7445558089999995,-4.695132607,-4.77117466,-2.152634703,-3.755903720855713,-6.165340423583984,-5.5353875160217285,-3.9119133949279785,-6.533749580383301 -4547,4547,G263K,-0.10162317900000001,0.011394885,-0.03864455,-0.22505367199999998,-2.214016011,0.038549788,-0.114286995,-0.08895936199999999,0.068048738,0.045046949,-0.022257179,0.02070558,-0.09799468,0.049669554000000005,-0.49977689799999997,-1.579069755,-2.8489622669999997,0.719369325,1.317873495,-3.900828882,-4.2940435180000005,-2.230540115,-5.191002502,-4.113692352,-3.6748659210000003,-4.251569175,-0.9772492840000001,-3.5219931602478027,-7.7575297355651855,-5.860593318939209,-3.5732192993164062,-5.073820114135742 -4548,4548,G263M,-0.010839136000000001,-0.011102727,-0.029771907,-0.00480984,-0.8520626170000001,0.13905444,0.002441457,-0.024119729,-0.016322493,-0.022860875,0.000655422,-0.026517463999999998,-0.033026348999999997,-0.0067588330000000005,-0.002860846,-0.719471848,-0.984653386,0.713026623,1.3941104380000002,-7.920160537999999,-8.531454437,-9.364031822000001,-5.402266441,-8.064323616,-8.238726372,-4.858404665,-3.581141265,-5.862906455993652,-10.115564346313477,-6.497694969177246,-5.938268184661865,-8.845426559448242 -4549,4549,G263L,-0.03898103,-0.007329136,-0.031712066000000004,0.008488045999999999,-1.341277354,0.040537604,-0.042065955,-0.035896104,0.135573327,-0.022400211,0.007741939000000001,-0.029132635,-0.034291496,0.031334506,-0.014358414,-1.043342157,-1.639212551,0.725923805,1.354505673,-7.5211431,-8.040713402,-9.767653037999999,-4.7001082080000005,-7.106046538999999,-7.991194312999999,-5.033801711000001,-3.3687566319999998,-5.035796642303467,-8.769192695617676,-5.204968452453613,-5.064304351806641,-8.134305953979492 -4550,4550,G263N,-0.019561347,-0.023802695,-0.042058324,-0.045793843,-0.200660416,0.054905657999999996,-0.048194485999999995,0.009071792,0.072664025,0.008325036,-0.055930426,0.010526655,-0.094643302,-0.023570621,-0.068017065,-0.122744207,-0.278576624,1.330674272,2.241012084,-2.263897566,-2.020483727,-1.6860614619999998,-4.323045563,-0.8376687159999999,-2.452228363,-2.431608272,-0.631879314,-3.853534698486328,-5.356854438781738,-4.863137245178223,-3.895995616912842,-6.351500988006592 -4551,4551,G263Q,-0.026182039,0.017507363999999997,-0.043068962999999995,-0.013681903,-0.622310764,0.058323691,-0.022008872000000002,-0.030355205,0.10121193,0.006632511,0.028382216000000002,-0.028713229,-0.057424697000000004,-0.00215089,-0.025212916000000002,-0.481254046,-0.763367482,1.049610639,1.586039056,-0.564383199,-0.537182617,0.05445731400000001,-1.4821103359999999,-0.373515274,-0.483565079,-1.6842511059999998,-0.9249558609999999,-0.6100239753723145,-4.090175628662109,-3.5269010066986084,-0.5489063262939453,-3.8946638107299805 -4552,4552,G263P,-0.00459036,0.005873155,-0.004649849,-0.551592643,-1.844063311,0.450544561,-0.010751443999999999,0.001570724,0.114019707,-0.018682509,0.030428818,-0.017861795,0.008562098,-0.276522463,-0.8266628229999999,-1.929750122,-1.7583764990000001,1.363374546,1.3467124719999999,-8.157052945,-8.992086411,-9.286438858,-7.435432564,-6.3620350189999995,-8.709271872999999,-5.4869853189999995,-2.82238441,-7.323159694671631,-10.643790245056152,-6.956599712371826,-7.047167778015137,-7.618751049041748 -4553,4553,G263S,-0.006300363000000001,0.026546155,-0.009453026,0.014407683999999999,-0.875088118,0.105867572,-0.023876408999999998,0.011275683,0.057746236,0.040528029,0.012564281000000002,0.033015748,-0.051921799000000005,0.025559109,0.0032562579999999997,-0.669822755,-1.080353481,0.7707009840000001,1.415085614,-5.800674097000001,-6.098882088,-5.922126777999999,-6.3729871220000005,-4.443068314,-6.166306183,-4.156345555,-0.804264173,-4.22432279586792,-5.492852687835693,-4.433485984802246,-4.278162956237793,-6.451181411743164 -4554,4554,G263R,-0.040506006000000004,-0.014057732,-0.031095533999999998,-0.013480012,-1.505519016,0.15935105800000002,-0.028646205,-0.052365805999999994,0.065087235,0.0045617470000000005,-0.03267721,0.0019072689999999998,-0.06409833599999999,0.036820093,-0.063780116,-1.4299754740000001,-1.5810625580000002,0.813330112,1.338763016,-3.9433476639999996,-4.418225533,-2.797971504,-4.97258654,-3.7519231410000002,-3.776031601,-3.896879717,-0.267572877,-4.255316734313965,-7.591776371002197,-6.089155197143555,-3.230001926422119,-5.608642101287842 -4555,4555,G263T,-0.055047609000000004,-0.01787746,-0.048022982,-0.00601571,-1.7170409640000002,0.18831633899999997,-0.044851112,-0.065244106,0.100637604,0.028962216000000002,-0.064717136,0.002765858,-0.098811821,0.07674677,-0.08877818900000001,-1.5565808209999998,-1.877501106,0.6495812870000001,1.315842272,-6.714000049,-6.89831282,-6.979839302,-6.074209023,-5.763407745,-7.8542313539999995,-4.15439875,-1.783626105,-4.842160224914551,-7.54653787612915,-4.6485819816589355,-4.635102272033691,-7.506318092346191 -4556,4556,G263W,-0.020392319,0.001424568,-0.010465341999999999,-0.652301284,-1.774132716,0.066486238,-0.008482811,-0.032301826,0.09730924699999999,0.004992836,-0.0021436999999999997,-0.040005888999999996,0.019075206,-0.23878879100000003,-1.065813776,-1.71438442,-1.833881012,1.284154901,1.3615696380000002,-9.306830794,-8.553217827000001,-8.801072502,-9.147896507,-10.83714317,-9.194823958999999,-6.250116515,-4.684196807,-8.473575592041016,-9.967337608337402,-7.987793922424316,-9.029566764831543,-10.395862579345703 -4557,4557,G263V,-0.035607663,0.017062146,-0.023432272999999997,-1.004819675,-2.019069464,0.238626232,-0.010877864,-0.060337460999999995,0.048494993,0.02872837,0.005395921999999999,-0.025896241,-0.020968305,-0.622222598,-1.387416751,-1.9213351109999999,-2.116803817,1.5104011119999998,1.354256014,-8.244447395,-9.137481361,-10.09663457,-5.128026596000001,-8.190919762,-8.66917469,-5.210399462,-3.682303366,-5.757481098175049,-8.299420356750488,-5.667297840118408,-6.295853614807129,-8.696832656860352 -4558,4558,G263Y,-0.100701284,-0.031957268,-0.04519089,-0.40684249100000003,-1.9925296069999998,0.063608752,-0.066167832,-0.135234736,0.125769344,0.012054236000000001,-0.075968772,-0.027206986000000002,-0.063174794,-0.110706894,-0.702978088,-2.098822817,-1.8862363969999998,0.697101523,1.288680203,-9.753437599,-7.218355422999999,-9.197708237,-10.58242555,-11.93368011,-9.835018677,-5.953697702,-2.977096242,-6.803229808807373,-7.813995361328125,-6.76209831237793,-6.980130672454834,-9.528759002685547 -4559,4559,S264A,0.014030355,0.00313289,-0.00468941,0.010981056999999999,-0.157365839,0.10126218699999999,-0.001750086,0.029810795,-0.039510244,0.007421411,-0.001155631,-0.00522176,-0.00415706,0.030654819,-0.008692706,-0.12782692,-0.186904757,1.5016806790000001,2.468476538,-2.875053424,-3.8807894210000002,-4.232066078,-1.700779808,-2.874291908,-1.687339905,-3.778166047,-0.444092331,-5.575096130371094,-3.8331210613250732,-5.827453136444092,-2.3130745887756348,-2.7196011543273926 -4560,4560,S264C,-0.061231732000000004,-0.020652297,0.007938299999999999,0.0031190040000000003,-0.83391204,0.197245261,-0.06488383,-0.057579634000000005,-0.11127163,-0.000793787,-0.040510806,0.021834764,-0.005958165,0.03090135,-0.024663342999999997,-0.43319563200000005,-1.234628448,0.7861573690000001,1.4981573680000002,-5.262163591,-4.658764473,-6.789347,-4.713685371,-5.934115723,-4.214905388,-3.950054783,-3.086343411,-10.085684776306152,-8.669312477111816,-10.272077560424805,-8.236701965332031,-9.145740509033203 -4561,4561,S264E,0.009047231,-0.006651471,-0.055327865999999996,-0.9745319570000001,-1.884315762,0.052465719,0.015055822,0.003038639,-0.058479227,-0.014600829,0.001297887,-0.078377858,-0.032277874,-0.511470599,-1.4375933140000001,-1.515706286,-2.252925238,2.082525151,1.706585842,-6.417645518,-8.415867989,-7.417650856,-6.1179005360000005,-5.406112679,-4.730695534,-4.148774767,-2.0886645269999997,-5.945491790771484,-9.187206268310547,-8.193504333496094,-3.9217326641082764,-6.945407390594482 -4562,4562,S264D,0.018067423,-0.026824037999999998,-0.043720325,-1.065546375,-1.703690832,-0.01962617,-0.010836018000000001,0.046970863,-0.052916713,-0.005694905,-0.047953170999999996,-0.07289923599999999,-0.014541413000000001,-0.7916934109999999,-1.339399339,-1.7595766369999999,-1.647805026,2.284575869,1.6990666630000002,-5.4977071429999995,-7.437304512000001,-5.83582177,-4.96013649,-5.48496936,-3.7703035810000003,-3.58429166,-0.861598106,-5.337041854858398,-9.07027530670166,-8.077600479125977,-4.764945030212402,-7.240988254547119 -4563,4563,S264G,0.007237908,0.011051018999999999,0.0005777719999999999,0.008649558,-0.061236874000000004,0.041796952000000005,-0.029260192999999997,0.043736008,-0.025330894,0.010216558,0.011885479,0.009074208,-0.007918665,0.041385054,-0.024085937999999998,-0.048978782,-0.073494965,1.2637275270000001,2.475357208,-5.452456357999999,-7.732986282000001,-6.3772957,-3.0032255780000003,-6.449733459,-3.6990407710000004,-2.929052827,-0.97637439,-6.6747822761535645,-6.523235321044922,-7.366490364074707,-4.648911476135254,-5.165443420410156 -4564,4564,S264F,-0.047248112,0.006769254000000001,-0.05140238900000001,-1.000720125,-2.164877315,0.055535945999999996,-0.016649745,-0.07784647900000001,0.013667106000000002,0.037400125,-0.023861617999999998,-0.073724446,-0.029080332,-0.398822742,-1.602617508,-1.732769559,-2.5969850709999998,1.2685669259999999,1.353155061,-7.722145206,-8.456375228999999,-8.103623024,-7.760581276,-7.1699593120000005,-7.120187187000001,-4.707118941,-1.9393215990000001,-8.694236755371094,-10.359928131103516,-9.484188079833984,-6.4080963134765625,-8.25651741027832 -4565,4565,S264I,-0.033589587000000004,-0.012891226,-0.02702467,-0.7222777840000001,-2.1641448569999997,0.075654895,-0.030953252999999997,-0.03622592,0.030057522000000003,-0.043866128,0.018083676,-0.105514847,0.051465507,-0.23560931300000001,-1.208946254,-1.72422794,-2.6040617740000003,1.3628674230000002,1.3744913680000002,-7.109113107000001,-8.258719879,-7.161000496000001,-6.7060257420000005,-8.298201195,-5.121618225,-5.128976596,-1.541540724,-8.129279136657715,-7.68084192276001,-7.778802871704102,-5.080410957336426,-6.2628254890441895 -4566,4566,S264H,-0.008587872,-0.006339224,-0.046946083,-0.214581068,-1.974231479,0.040956652999999996,-0.025746982999999998,0.00857124,0.030057522000000003,0.00697195,-0.019650398,-0.093980566,8.840000000000001e-05,-0.0060111159999999995,-0.42315101899999996,-1.779610079,-2.168852879,0.714015707,1.307921458,-5.922316867,-8.265671783,-7.062484726,-5.902382957,-5.209924622,-3.1711202469999997,-4.930202457,-2.178370395,-7.534908771514893,-9.651766777038574,-9.100617408752441,-5.306504249572754,-8.157730102539062 -4567,4567,S264K,-0.039657526,-0.034307361,-0.073494226,-0.168587018,-1.853998581,0.155476683,-0.037307169,-0.042007882999999996,0.04908076,-0.0010015339999999999,-0.067613187,-0.067089024,-0.079899428,0.043843447,-0.381017482,-1.468955435,-2.239041726,0.597885699,1.316738267,-5.056724313,-6.968138382,-5.191095184,-4.399631905,-5.127989655,-3.596766441,-4.021337011,-2.464426465,-6.575202941894531,-8.71407699584961,-8.03608226776123,-4.0158491134643555,-6.837838172912598 -4568,4568,S264M,0.023053182999999998,-0.045848402999999996,-0.069584432,-0.007477978000000001,-1.52296629,0.061818995999999994,0.029275281,0.016831085,-0.073075855,-0.080248279,-0.011448526,-0.13363458,-0.005534283,0.031797778,-0.046753733,-1.443318378,-1.6026142019999998,0.5722636489999999,1.316109343,-7.922894038,-9.076979454,-7.029837952,-8.045745644,-8.39584037,-7.066066772,-5.492778447,-2.925700202,-8.885330200195312,-7.393707275390625,-8.070284843444824,-4.946408271789551,-6.719776153564453 -4569,4569,S264L,-0.041432687,-0.030345465,-0.020574312,-1.047610989,-2.185465744,0.037060113,-0.031695747,-0.051169627,0.018358647,-0.005608401,-0.055082528,-0.023675761,-0.017472863,-0.46325130200000003,-1.631970675,-1.9811194380000001,-2.38981205,1.595624795,1.372003958,-7.826166499,-9.651219727,-7.781398727000001,-8.754852638,-7.990710289,-4.952651115,-4.331150296000001,-0.9544664820000001,-7.611207962036133,-8.376380920410156,-7.848676681518555,-3.9293735027313232,-6.8443603515625 -4570,4570,S264N,-0.046606409,-0.010337215,-0.055456806,0.023379266,-1.146017061,0.08877749199999999,-0.068721582,-0.024491236,-0.114434751,0.00534499,-0.026019419,-0.059124486,-0.051789125,0.079454035,-0.032695503,-0.7150734670000001,-1.576960654,0.541930145,1.365331674,-0.322673293,-1.2783722690000001,-0.5346699979999999,0.054650536,0.062300659,0.082724609,-1.8315957790000001,-1.1577307559999999,-6.099532604217529,-6.633726119995117,-6.339459419250488,-4.690603256225586,-6.364315509796143 -4571,4571,S264Q,-0.017732408999999998,0.006009731,-0.030076212,-0.032417856,-1.79312276,0.124951235,-0.020531708,-0.014933108999999998,-0.040032546,0.023418415,-0.011398953,-0.038867097,-0.021285327000000003,0.046852972,-0.11168868400000001,-1.890589522,-1.695655998,0.586879577,1.299008959,-6.608459448,-9.616764198,-6.672174316,-6.946134224,-5.603032211,-4.204192291,-4.46778332,-1.6794296130000002,-6.993979454040527,-9.47708511352539,-8.424406051635742,-3.706876516342163,-7.394136905670166 -4572,4572,S264P,-0.034996624,-0.040449641,-0.110291679,-1.5169768069999998,-2.326807229,0.123103992,-0.021715626000000002,-0.048277621,0.057076365,-0.042554357,-0.038344924,-0.08117772,-0.139405637,-1.155309702,-1.8786439119999998,-2.021352885,-2.632261573,2.542090258,1.726625805,-6.001946898,-6.542418121,-5.977127997999999,-4.797720665,-7.061855209,-5.630612495,-3.124230551,-0.40762467,-5.845623970031738,-7.062692642211914,-7.269484519958496,-2.4800267219543457,-5.72202205657959 -4573,4573,S264R,-0.033303892,-0.002158925,-0.01905306,-0.37248958600000004,-1.654599757,0.24496117399999998,-0.032306874,-0.03430091,-0.011666812,0.009141283,-0.013459132,-0.01837351,-0.01973261,-0.038957162999999996,-0.706022009,-1.482227449,-1.826972064,0.669185008,1.319673223,-7.542838615,-10.02817562,-10.15477362,-6.442379288,-7.071416367,-4.017448181000001,-4.117887259,-1.50347734,-8.087170600891113,-9.62924575805664,-8.898405075073242,-4.2802228927612305,-7.877082347869873 -4574,4574,S264T,-0.00930879,-0.025102462000000002,-0.029694652999999998,0.005860733000000001,-0.031791011,0.00356107,-0.025066334,0.006448755,0.072809503,-0.04432208,-0.005882844,-0.061890586,0.002501281,0.023128661000000002,-0.011407195,-0.037601047,-0.025980974,1.346499602,2.330677863,0.6832391170000001,0.7719685209999999,0.7824042659999999,0.713986382,0.23606063800000002,0.91177578,-0.800783747,-0.333621792,-3.900585174560547,-1.3711509704589844,-1.7228775024414062,-2.9811601638793945,-2.0575919151306152 -4575,4575,S264W,-0.03701137,-0.036335358,-0.040632846,-1.247204822,-2.23411749,0.048382807,-0.020247011999999998,-0.053775727,-0.010028430999999999,-0.044897094000000005,-0.027773622,-0.052056143,-0.029209548,-0.7875832770000001,-1.706826367,-1.9535261769999999,-2.514708802,2.034163654,1.49591539,-9.473682346,-10.28819713,-10.10367625,-8.30988456,-9.432535858,-9.234117928,-5.572706863,-3.226737777,-11.517963409423828,-11.819822311401367,-11.17961311340332,-8.553194046020508,-10.692262649536133 -4576,4576,S264V,-0.050420781,-0.020685394,-0.017367231,-0.299916642,-1.8695541480000002,0.064164998,-0.04680721400000001,-0.054034347999999996,-0.052773279000000006,0.001802319,-0.043173105999999996,-0.021708752999999997,-0.013025709,-0.019476246000000003,-0.5803570379999999,-1.6244296169999999,-2.114678679,0.78747563,1.319902724,-5.563815404,-6.643668869,-6.443362473,-4.921221222,-6.090290092,-3.720534363,-4.004210165,-1.308830387,-7.480714797973633,-6.357592582702637,-6.8675127029418945,-4.040835380554199,-4.936373710632324 -4577,4577,S264Y,-0.060755017,-0.050137142,-0.023876903999999997,-1.0606901709999998,-2.3589679969999997,0.06166054,-0.050158299,-0.071351735,0.061946667000000004,-0.005199179,-0.09507510400000001,-0.0032937009999999996,-0.044460106,-0.39884257799999995,-1.7225377640000001,-1.6961056280000002,-3.021830366,1.634918919,1.443603763,-7.871698178,-9.174095192000001,-8.485197533,-7.22027623,-7.01420842,-7.464713516000001,-4.738063775,-2.986202946,-9.327630043029785,-10.425558090209961,-9.537779808044434,-6.9334821701049805,-9.090751647949219 -4578,4578,Q265A,0.042492765,0.016703217,-0.002868155,-0.019031266,0.007296149,-0.014248718999999998,0.024572262,0.060413268,0.012031506,-0.010741734,0.044148168,-0.002731134,-0.003005175,-0.026598755,-0.011463777,-0.003314102,0.017906400000000003,1.3428298580000002,2.71359507,-1.129456656,-1.251494225,-0.42283254200000003,-0.18342443100000003,-2.214410004,-1.5751220780000001,-2.311807489,0.593920614,-2.9600932598114014,-3.9594991207122803,-3.3620991706848145,-3.2205090522766113,-1.1039927005767822 -4579,4579,Q265C,0.015635141,0.012609201,-0.020334917,-0.038009941,-0.045596657,0.052913892000000004,0.014886568999999999,0.016383711999999998,-0.027470312,0.00121696,0.024001441000000002,-0.001143472,-0.039526361,-0.031116185,-0.044903697,-0.0236488,-0.067544513,1.307121673,2.5635055980000003,-6.134131061000001,-6.7742260739999995,-6.044303597000001,-5.361483208,-7.08680056,-5.4038418660000005,-6.773408159,-4.7671361789999995,-8.904233932495117,-9.927528381347656,-10.858907699584961,-7.185965061187744,-7.551243782043457 -4580,4580,Q265E,0.08193562900000001,-0.002519987,-0.02770598,-0.018491827,0.02715064,-0.036268159,0.06425998,0.099611277,0.004952186,-0.026515012999999997,0.02147504,-0.037661528,-0.017750431,-0.05391181900000001,0.016928165,0.004552804000000001,0.049748475,1.226168769,2.5823727919999997,0.437351463,0.344221741,0.348820671,1.244198463,0.158474792,0.091041649,-2.053026874,0.7069593059999999,-1.1945805549621582,-3.434671640396118,-2.5246715545654297,-4.069019317626953,0.14962077140808105 -4581,4581,Q265D,0.020641448,0.063860532,0.018170383999999998,-0.028453658,0.018464877,-0.011419163999999999,0.010613512,0.030669383999999997,-0.058423798,0.072015577,0.055705487000000005,0.059575120999999995,-0.023234354,0.039229638,-0.09613695300000001,0.074702899,-0.037773146,0.850566594,2.7485039689999997,0.22936678600000002,-0.11594793699999999,0.315224503,1.4300998,0.09733943199999999,-0.579881866,-1.116198971,0.647873967,-0.33414173126220703,-4.555387496948242,-2.5545654296875,-4.218343257904053,0.19604063034057617 -4582,4582,Q265G,0.040053063,0.01710046,-0.006608361,-0.031994063999999996,0.021784772999999997,-0.025236466000000003,0.019856672,0.060249453,0.007423393,-0.010085965,0.044286884000000006,-0.009594656,-0.0036220659999999997,-0.031167682000000002,-0.032820446,0.019872636000000003,0.02369691,1.204277377,2.578432526,-1.86489353,-2.130836327,-1.1560665970000001,-0.55668821,-1.970527275,-3.5103492430000003,-2.9377711019999997,0.04205366,-3.9803550243377686,-5.260837554931641,-4.996192932128906,-4.331918716430664,-2.160414934158325 -4583,4583,Q265F,-0.022871247,-0.03495527,-0.029046292999999997,-0.090125515,-0.072124116,0.051579800999999995,0.013891222,-0.059633715999999996,0.075610763,-0.055334234,-0.014576306,-0.052014193,-0.0060783930000000005,-0.08617291,-0.09407812,-0.055704777999999996,-0.08854345400000001,1.279019596,2.339457639,-6.134996567999999,-7.879184013,-5.207175606,-4.509172096,-6.066465126000001,-7.012986,-5.200715709,-1.584151303,-7.766280174255371,-7.7897186279296875,-7.212438106536865,-6.497336387634277,-4.687246322631836 -4584,4584,Q265I,0.080185498,0.035607078,-0.000988701,0.005143107,0.013407068000000001,-0.085509895,0.100398609,0.059972385999999996,0.026559745,0.023815904,0.047398250999999995,0.004361564,-0.006338966,-0.024131438999999998,0.034417653,0.022708427000000003,0.004105708,1.136173339,2.5670765490000003,-5.068337535,-5.870093987000001,-4.451726433,-3.931287582,-4.430952339,-6.657627335,-4.471046367,-2.183539496,-5.737632751464844,-5.867685317993164,-5.557322978973389,-5.433460235595703,-2.8866689205169678 -4585,4585,Q265H,0.045765925,-0.017652906,-0.001297824,-0.025484391000000002,-0.011547412,-0.017816485,0.033014042,0.058517808,0.010030312,-0.035788245,0.000482434,-0.004678449,0.002082802,-0.044078275,-0.006890507,-0.0028840240000000002,-0.0202108,1.2296809659999999,2.557797511,-1.8454045559999999,-2.508680115,-1.968893433,-1.4454149630000002,-1.920941002,-1.383093269,-2.180157505,-0.690860385,-5.264163017272949,-4.757473945617676,-5.571517467498779,-4.839326858520508,-2.0035552978515625 -4586,4586,Q265K,0.010971079,-0.031122139,-0.01571936,-0.024909355,0.031578232000000005,-0.014083993000000001,0.022342211,-0.00040005300000000004,-0.022185543,-0.028182328,-0.034061949,-0.036885,0.00544628,-0.037527111,-0.012291598999999999,0.034160832,0.028995632,1.151166808,2.571170035,0.080061525,0.480068321,-0.002937141,0.744700615,-0.270477417,-0.551046753,-1.629402059,0.806842299,-3.0747931003570557,-2.926079034805298,-3.449380397796631,-3.0678839683532715,-0.7780449390411377 -4587,4587,Q265M,0.02582843,-0.020914929,-0.029816699,-0.02550843,0.012483781999999999,-0.017426228999999998,0.020487003,0.031169857000000002,-0.022616796,-0.015085551,-0.026744306000000002,-0.013464323,-0.046169075,-0.004050728,-0.046966130999999994,0.00538879,0.019578774,1.177100104,2.659550514,-4.756326613,-5.212896141,-5.035090607,-3.9860657880000003,-4.619007965,-4.928572563,-4.499075856,-1.692107595,-6.313529014587402,-6.727393627166748,-6.159343242645264,-5.644861698150635,-3.483844041824341 -4588,4588,Q265L,0.035553355,0.020213109,0.0090118,-0.007238046999999999,0.009050001,-0.006434513,0.05102574,0.020080969,0.029917935,0.000399528,0.04002669,0.002464594,0.015559006,-0.013051078,-0.001425015,0.014565121,0.00353488,1.165991797,2.640183532,-4.5522723019999995,-5.704207877999999,-5.106309517,-3.3507104639999996,-3.331065086,-5.269068565,-4.201444347,-1.014486933,-5.674644470214844,-6.074886322021484,-5.277657985687256,-5.021592617034912,-2.9117844104766846 -4589,4589,Q265N,0.035372497,0.009299083,-0.035646392,0.002078983,0.057900198,-0.03121396,-0.014231925,0.08497691800000001,0.07029761799999999,-0.025783485,0.044381650999999994,-0.019869038999999998,-0.051423744,-0.009376849,0.013534814,0.021476562,0.09432383400000001,1.4418159069999998,2.7830227260000004,-1.079458675,-1.4961757580000001,-0.698349777,-0.71786219,-0.8815245740000001,-1.6033810730000002,-2.922086161,-0.412021855,-2.719827651977539,-4.359952926635742,-3.485124111175537,-3.619558572769165,-0.34944939613342285 -4590,4590,Q265P,0.033479285,0.014454858000000001,0.000129577,-0.020894173000000002,-0.002765732,-0.029154499,0.016946423000000002,0.050012147,0.008520324000000001,-0.004877412,0.033787127,0.0023975389999999997,-0.002138386,-0.026811322000000002,-0.014977023999999999,0.002547557,-0.008079021,1.26423606,2.658294344,-0.999888963,-0.130305054,-0.652441811,-0.057754715,-2.016401833,-2.142541405,-1.342867274,0.267389005,-5.428774833679199,-6.314733982086182,-4.934075355529785,-4.598039150238037,-2.281770944595337 -4591,4591,Q265S,0.032842689,-0.003225752,-0.020299962,-0.035852091,0.025386272,-0.025072192000000004,0.011754074,0.053931304000000006,0.003176281,-0.024987371,0.018535867,-0.018954552,-0.021645372000000003,-0.028632496,-0.043071686,0.011617872,0.039154671,1.20546845,2.53240831,-0.8557982479999999,-0.997512947,-0.419145889,-0.43603694200000004,-1.684705551,-0.741589912,-1.650033429,0.42440759100000003,-3.2283389568328857,-3.8346498012542725,-3.436333179473877,-2.636101245880127,-0.729337215423584 -4592,4592,Q265R,0.025854331,0.015738455,-0.01280294,-0.030861200000000002,0.011668405,-0.00463903,0.04020749,0.011501171000000001,0.003813734,-0.03355897,0.065035879,-0.019924399,-0.00568148,-0.045407092999999996,-0.016315307,-0.008409514,0.031746323,1.279762208,2.5935537369999997,-1.053425443,-1.591141479,-1.532817093,-0.444491821,-1.576588264,-0.122088554,-2.505593958,0.508513684,-5.521209716796875,-4.740882396697998,-5.830931186676025,-4.132429122924805,-3.088667154312134 -4593,4593,Q265T,0.038330228,0.01880192,-0.0019082460000000002,-0.04940008,0.016477116,0.000456617,0.023889612,0.052770844000000004,0.025697313,-0.021200449,0.058804289,0.0067052990000000005,-0.01052179,-0.045376997,-0.053423162,0.013202536,0.019751695,1.308775547,2.591379482,-0.172983107,-0.046226387,0.533442772,0.508756027,-1.696491501,-0.164396446,-1.944324161,0.92285851,-3.1408486366271973,-3.312251091003418,-2.987198829650879,-1.8773144483566284,-0.08061790466308594 -4594,4594,Q265W,0.048525862,0.028786002,-0.013611858999999999,-4.59e-05,-0.033193385,-0.027001742000000002,0.034624267,0.062427456,0.050752980999999996,-0.002604965,0.060176969000000004,0.006136295,-0.033360013,0.0011382410000000001,-0.0012300030000000001,-0.040141500000000004,-0.02624527,1.34675048,2.55281712,-5.824503432,-6.590552513,-5.337723747,-4.26220787,-5.549509895,-7.382523132,-5.481224246,-2.605343291,-9.51127815246582,-10.87405776977539,-9.9575834274292,-8.6529541015625,-7.015366554260254 -4595,4595,Q265V,0.004879323,-0.014099698,-0.048829454,-0.012788863999999999,-0.015321831999999999,-0.045433935999999994,-0.008662755,0.018421401,0.012494983999999999,-0.011635092,-0.016564304,-0.043106267000000004,-0.054552641,0.005887526999999999,-0.031465255,0.007340592,-0.037984255,1.222735381,2.6658805709999998,-3.29796792,-3.975531593,-2.5182025219999997,-1.8681586380000001,-3.163455917,-4.964490929,-3.772100333,-0.428144896,-4.912510871887207,-4.849508762359619,-4.5131516456604,-4.487856864929199,-1.986393928527832 -4596,4596,Q265Y,0.119990645,0.071117446,0.006734652,0.02416805,0.036114718,-0.006760913,0.111442961,0.128538328,-0.004378883,0.003970088,0.138264804,-0.019849308,0.033318611,-0.0048204829999999995,0.053156583,-0.004563354,0.076792789,1.180671504,2.553011113,-4.794675983,-6.086442947,-4.037893433,-3.526507057,-4.862276871000001,-5.460259605,-4.971919866,-1.209698856,-7.641631126403809,-7.249999046325684,-7.170229911804199,-6.810357093811035,-4.475379943847656 -4597,4597,A266C,0.518992387,-0.016049777,0.031559422999999996,0.043112156,0.001832707,,0.518992387,,0.028396723999999998,-0.016049777,,0.031559422999999996,,0.043112156,,0.001832707,,1.203283939,2.544351378,-9.611312599,-10.46384925,-9.678318954,-10.77058944,-8.699876961000001,-8.443928391,-7.485041592000001,-5.6720472079999995,-9.987464904785156,-9.722877502441406,-11.026049613952637,-8.380188941955566,-11.204239845275879 -4598,4598,A266E,-0.048413773,-0.019240548,-0.015483557,0.030011612000000003,0.035025403,,-0.048413773,,0.026226022999999998,-0.019240548,,-0.015483557,,0.030011612000000003,,0.035025403,,1.1075174509999999,2.634571048,-7.519382848999999,-9.149027359,-6.131167389,-8.497146118,-6.732920784,-7.086652596,-5.072615722,-0.538610415,-4.066763401031494,-6.055423736572266,-6.123164176940918,-8.419260025024414,-7.582742214202881 -4599,4599,A266D,0.19884235100000003,-0.012641397,-0.032308955,4.07e-05,-0.064810058,,0.19884235100000003,,0.029611426,-0.012641397,,-0.032308955,,4.07e-05,,-0.064810058,,1.4758646819999999,2.5448878230000003,-9.38283797,-11.84464311,-8.755695053,-10.53382947,-7.9186575779999995,-7.861364639,-4.86006911,-0.816376268,-5.263916492462158,-6.847752571105957,-7.56050443649292,-9.11674976348877,-9.111430168151855 -4600,4600,A266G,0.061345422000000004,-0.024056809,-0.039491087,-0.000816358,-0.009499068000000001,,0.061345422000000004,,-0.009162203,-0.024056809,,-0.039491087,,-0.000816358,,-0.009499068000000001,,1.671448915,3.643209181,-7.140749799,-8.363322487000001,-6.848897002999999,-7.263406754,-5.382646675,-7.845476074,-5.035819876000001,-1.6826594330000002,-6.024308681488037,-5.926837921142578,-7.566945552825928,-6.756678581237793,-7.043869972229004 -4601,4601,A266F,0.29728185,-0.0037698740000000003,-0.136154465,0.007059595,-0.0305753,,0.29728185,,0.076606455,-0.0037698740000000003,,-0.136154465,,0.007059595,,-0.0305753,,1.323380862,2.587888183,-11.68021708,-12.26620926,-11.31065618,-14.78654055,-11.69767136,-8.340008034,-6.17774331,-4.104502726000001,-8.534143447875977,-7.775680065155029,-8.845813751220703,-9.257538795471191,-10.665351867675781 -4602,4602,A266I,0.162639222,-0.128283154,-0.17685156,-0.066386457,-0.24631791600000003,,0.162639222,,-0.059967169,-0.128283154,,-0.17685156,,-0.066386457,,-0.24631791600000003,,1.577214132,2.155083963,-7.742071185,-7.810437935,-7.847771866,-8.836214111,-6.9441707,-7.271761314,-4.735737828,-3.0565022219999998,-6.32169246673584,-6.201026916503906,-6.285483360290527,-8.11767864227295,-7.75757360458374 -4603,4603,A266H,0.395601821,-0.004856734000000001,-0.065801242,-0.011242262,-0.00282678,,0.395601821,,-0.041560177999999996,-0.004856734000000001,,-0.065801242,,-0.011242262,,-0.00282678,,1.340953251,2.612234521,-9.998361209,-12.16593826,-9.594224266,-11.02974333,-9.094475098,-8.107425095,-5.4981294510000005,-3.344430205,-7.518072128295898,-7.260684967041016,-8.641931533813477,-9.168523788452148,-9.531167984008789 -4604,4604,A266K,-0.351159866,-0.056209012,-0.172911542,-0.069206022,-0.193697368,,-0.351159866,,-0.112633107,-0.056209012,,-0.172911542,,-0.069206022,,-0.193697368,,1.440037801,2.125370507,-7.974927737000001,-10.09508927,-6.280436195,-9.576574768,-6.556133965,-7.366404488,-3.996761111,-0.973117993,-5.5507988929748535,-4.591862678527832,-7.259784698486328,-8.853738784790039,-7.4842023849487305 -4605,4605,A266M,0.34603790700000003,-0.019240548,0.04152471,0.03608576,0.062910106,,0.34603790700000003,,0.11953191099999999,-0.019240548,,0.04152471,,0.03608576,,0.062910106,,1.20498797,2.904508155,-10.01064075,-10.97800371,-8.981156006,-11.61887756,-10.30487699,-8.170289505,-6.891870127000001,-3.844259075,-6.973855018615723,-6.203627586364746,-7.225704193115234,-7.555645942687988,-8.268838882446289 -4606,4606,A266L,0.37505988700000004,-0.081977752,-0.056799224,-0.009644789,-0.008888088,,0.37505988700000004,,0.017646771999999998,-0.081977752,,-0.056799224,,-0.009644789,,-0.008888088,,1.287897993,2.596848787,-7.8031871839999996,-8.377955833,-6.980594543,-9.789633011,-8.096917603,-5.77083493,-3.451767255,-1.2713776190000001,-5.895608901977539,-4.493088722229004,-6.075580596923828,-7.2103657722473145,-7.598324775695801 -4607,4607,A266N,0.37774374200000005,-0.10257775400000001,-0.073634209,-0.0024391020000000003,0.08711741,,0.37774374200000005,,0.068568172,-0.10257775400000001,,-0.073634209,,-0.0024391020000000003,,0.08711741,,1.215730156,2.850969187,-10.28339501,-13.39398823,-10.64214191,-12.18014978,-9.699234589,-5.501460563999999,-5.700605346000001,-1.420583421,-7.128758907318115,-7.140863418579102,-8.418828964233398,-8.555085182189941,-8.945558547973633 -4608,4608,A266Q,0.228487823,0.014199503999999998,-0.10046496699999999,-0.023102157999999998,-0.066046697,,0.228487823,,-0.012653862,0.014199503999999998,,-0.10046496699999999,,-0.023102157999999998,,-0.066046697,,1.323575639,2.34226023,-7.997626971,-9.324178291,-7.001599434,-8.656268447999999,-7.305933112999999,-7.700155571,-3.8692733999999995,-1.482195156,-5.373964309692383,-5.019972801208496,-6.750056743621826,-7.982539653778076,-7.966104507446289 -4609,4609,A266P,0.270350037,-0.057978523,-0.041024541,-0.174650781,-1.653566087,,0.270350037,,-0.011037471,-0.057978523,,-0.041024541,,-0.174650781,,-1.653566087,,1.210007353,1.35822011,-6.962914457999999,-9.598865906,-6.466596924,-7.479864662000001,-7.487980437999999,-3.7812643589999997,-4.093011225,-0.8461807370000001,-6.29853630065918,-5.921126842498779,-7.603391170501709,-7.258647441864014,-7.320597171783447 -4610,4610,A266S,0.342687258,-0.031926298,-0.024562632,0.013874632,-0.018780831,,0.342687258,,-0.029094093999999997,-0.031926298,,-0.024562632,,0.013874632,,-0.018780831,,1.084257502,2.531067067,-4.845742529,-6.183047615,-4.620822983,-5.760386131000001,-4.541211754,-3.123244164,-4.170367827,-1.842786845,-6.023282527923584,-5.2117743492126465,-6.070137023925781,-6.125588417053223,-6.550450325012207 -4611,4611,A266R,0.318462859,-0.053024392000000004,-0.058928724,-0.0035292929999999998,-0.0033143129999999997,,0.318462859,,-0.006296708000000001,-0.053024392000000004,,-0.058928724,,-0.0035292929999999998,,-0.0033143129999999997,,1.187372712,2.582314897,-7.651654289,-9.359199837,-5.270740295,-8.895946067999999,-5.848240722999999,-8.884144524,-4.005418543,-1.3899803080000002,-7.23300313949585,-5.784488677978516,-9.011165618896484,-8.73914909362793,-8.797640800476074 -4612,4612,A266T,0.140331348,-0.06770393200000001,-0.031762258,-0.008374882,0.018746703,,0.140331348,,-0.039526008,-0.06770393200000001,,-0.031762258,,-0.008374882,,0.018746703,,1.32210033,2.819818423,-4.942971735,-4.974907532,-5.545647827000001,-5.968902817000001,-4.4679534069999995,-3.75744709,-3.900351198,-1.9959591890000001,-5.502058506011963,-5.114171504974365,-5.376709461212158,-6.263147830963135,-6.2099175453186035 -4613,4613,A266W,0.377702152,-0.084947144,-0.08161323599999999,-0.001309972,-0.663916399,,0.377702152,,-0.019545738,-0.084947144,,-0.08161323599999999,,-0.001309972,,-0.663916399,,0.94292984,1.4689113280000001,-13.73109786,-14.65528414,-13.19512041,-16.38514017,-12.860026800000002,-11.55991778,-8.295016865,-5.767743586,-9.705347061157227,-9.918201446533203,-11.319881439208984,-10.72257137298584,-12.229401588439941 -4614,4614,A266V,0.254376094,-0.019583128,-0.062954898,-0.029222623,-0.017698685,,0.254376094,,-0.019365261,-0.019583128,,-0.062954898,,-0.029222623,,-0.017698685,,1.543610422,3.106887046,-5.093455186,-5.759747803,-5.173669151,-6.429858025,-4.742464447,-3.361536507,-3.987818968,-1.7647184280000001,-5.250633239746094,-5.274790287017822,-3.52336049079895,-6.19435977935791,-5.769083499908447 -4615,4615,A266Y,0.400417842,0.0059141309999999996,-0.14388835,-0.037100529,-0.05505783400000001,,0.400417842,,0.099842444,0.0059141309999999996,,-0.14388835,,-0.037100529,,-0.05505783400000001,,1.456235439,2.55298152,-12.25742843,-12.64483664,-12.3985679,-15.19356399,-11.50240115,-9.547772491,-5.817980467000001,-2.904006218,-8.596370697021484,-8.033599853515625,-9.043699264526367,-9.526580810546875,-10.93466854095459 -4616,4616,T267A,0.03211872,-0.006044195,-0.01483234,-0.009837333,-0.036951636,-0.018845395,0.030240737,0.033996702000000004,0.033248937,-0.049205145,0.037116756,-0.021773687000000003,-0.007890993,-0.027901755,0.008227089,-0.055808522,-0.018094749,1.3873978809999998,2.505001121,-3.255449571,-2.3577817690000002,-3.271479462,-4.3259276280000005,-2.823833847,-3.498225151,-3.5009302630000003,-0.312082038,-4.914567947387695,-5.269305229187012,-4.451096534729004,-4.6762919425964355,-4.499683380126953 -4617,4617,T267C,0.052386228,-0.007988031,-0.017080153,0.016619859,-0.12178815400000001,-0.001304381,0.048250601,0.056521854,0.012554947,-0.070516827,0.054540765,-0.016327905,-0.0178324,0.00561382,0.027625897000000003,-0.10771884400000001,-0.135857463,1.1764504690000002,2.129149516,-8.903374516,-7.485360588,-9.472220299,-9.863099419,-8.662179108,-9.034013168,-9.301718035,-7.784834906,-9.739513397216797,-8.71005630493164,-10.922660827636719,-9.857867240905762,-10.328561782836914 -4618,4618,T267E,0.018413898999999997,0.014205472,-0.012188842,-0.033622154,-0.06588998900000001,-0.015705672,0.01059256,0.026235237999999998,0.036998691,-0.0015499589999999998,0.029960902999999997,-0.024390584,1.29e-05,-0.051035639,-0.016208669,-0.087593311,-0.044186666,1.400858968,2.3718612130000003,-4.128007426,-3.669506615,-4.261348152,-6.183581947,-2.679595703,-3.846004715,-4.299408328,-0.308536818,-5.007414817810059,-5.239624977111816,-3.7076544761657715,-5.963621139526367,-4.730574131011963 -4619,4619,T267D,0.061858767,-0.027677447999999997,0.009052366,-0.010730389,-0.036252419,0.029058135,0.05749765,0.066219884,0.048856577000000005,-0.06579162,0.010436724,-0.007860925999999999,0.025965658,0.00976978,-0.031230557000000003,-0.043956457000000004,-0.02854838,1.30825329,2.4626432769999997,-3.4063753460000004,-3.018718948,-5.195660995,-4.065742531000001,-2.483276581,-2.268477676,-2.79502083,1.541141925,-3.621575355529785,-3.5311551094055176,-3.1561384201049805,-5.575841903686523,-3.2443933486938477 -4620,4620,T267G,0.010315961,-0.017527341000000002,-0.035547423,-0.007020734,-0.024747957,-0.022717051000000002,0.0062245059999999994,0.014407415,0.040941757,-0.03663045,0.001575768,-0.018681014,-0.052413832,0.00040683,-0.014448298,-0.014541433000000001,-0.03495448,1.210797152,2.526777108,-4.98173965,-4.02829277,-4.5015637889999995,-5.945257499999999,-5.067787972,-5.365796219,-4.370599726,-0.786540949,-5.327370643615723,-4.250192642211914,-5.048385143280029,-5.4309611320495605,-4.43422794342041 -4621,4621,T267F,0.000910825,0.005383098,-0.00542894,-0.004803304,-0.90864056,0.024608988999999998,0.004806471,-0.002984821,0.046489370999999995,-0.003090474,0.013856668999999999,0.013920623,-0.024778502,-0.011535136000000001,0.0019285279999999999,-0.627623814,-1.189657305,0.593006041,1.385254969,-8.949584862,-7.236138779,-10.97009499,-10.07858456,-7.793717125,-8.669388855,-7.2094124520000005,-3.768400077,-9.74166202545166,-8.828688621520996,-9.580039978027344,-9.95146369934082,-10.868700981140137 -4622,4622,T267I,0.045688049,-0.026957818999999997,0.005237958,0.000362835,-0.28823761800000003,-0.054456405,0.064213678,0.02716242,0.002349416,-0.076006548,0.022090911,-0.016885516,0.027361431000000002,-0.038437775,0.039163445,-0.249389463,-0.327085773,1.254612817,1.924629416,-7.990148303,-6.899457901,-8.301415732999999,-9.220891014,-7.895884682,-7.633092186,-6.809061037,-3.355514165,-8.37843132019043,-7.965864658355713,-7.8082122802734375,-8.544456481933594,-8.49726676940918 -4623,4623,T267H,0.037923684,0.012100927,0.009698776,-0.027518157999999997,-0.034456457999999995,-0.028717992,0.02055315,0.055294217,0.057467101,-0.02328553,0.047487384,-0.000500253,0.019897805,-0.022008049,-0.033028267,-0.049272559,-0.019640357,1.321427578,2.414619047,-6.873257555,-5.648542435,-8.540943253,-7.926379997000001,-4.910652985,-7.339769104,-5.275638569,-1.6164004980000002,-7.285470008850098,-6.950474739074707,-7.040615558624268,-8.09713363647461,-6.949868679046631 -4624,4624,T267K,-0.03611238,-0.014509778999999999,-0.018261061999999998,-0.063844271,-0.121983019,-0.042151835,-0.036885712,-0.035339047,0.088986119,-0.055874952,0.026855395,0.0016696920000000002,-0.038191816,-0.08710999900000001,-0.040578542,-0.04647047,-0.197495568,1.221921648,2.3451008030000002,-4.603173033,-4.25847625,-5.786440056,-5.705941887000001,-2.955097977,-4.309908997,-4.649029807,-1.30458173,-5.677803039550781,-5.818180084228516,-5.607011795043945,-5.593492031097412,-4.839503765106201 -4625,4625,T267M,-0.008897263,0.008307999,-0.009642578,-0.015124475,-0.172746861,-0.029690465,-0.061562867,0.043768340999999995,-0.025272205,-0.025207733,0.041823731,0.01200675,-0.031291905,0.024637057,-0.054886007,-0.14197628199999998,-0.203517439,1.352136281,2.22547064,-8.39117921,-7.0232622529999995,-9.524322037000001,-9.651534805,-8.062188965,-7.69458799,-6.963229811000001,-3.98240907,-9.044065475463867,-8.15544319152832,-8.373262405395508,-8.327516555786133,-8.594058990478516 -4626,4626,T267L,0.0027207209999999997,-0.009713904,-0.028805222000000002,-6.670000000000001e-05,-0.154958829,-0.000711953,-0.007764748,0.013206188999999998,0.037062531,-0.04505272,0.025624912000000003,-0.016498233,-0.041112211,-0.019024258,0.018890904,-0.148005568,-0.16191209,1.419723899,2.2373952530000003,-7.817072112999999,-6.0079086760000004,-8.935391541,-9.564654678,-7.686483977999999,-6.890921692,-5.750315952,-2.8720172269999997,-7.405925750732422,-7.351506233215332,-7.294856071472168,-6.89369535446167,-7.712759494781494 -4627,4627,T267N,0.019529344,0.037702328,-0.018547291,-0.008369744,0.07182240200000001,-0.043361142000000005,-0.033438609,0.072497296,0.00852039,-0.000650399,0.076055054,-0.012979435,-0.024115147000000003,0.047568923,-0.064308411,0.017068227,0.126576576,1.106124803,2.581262974,-3.955632893,-3.500690857,-5.487015952999999,-3.554760078,-3.170759445,-4.064938133,-4.17054663,-0.055879196,-4.341684341430664,-3.4565234184265137,-4.114819526672363,-5.436274528503418,-3.685457706451416 -4628,4628,T267Q,0.008167373,-0.02651603,-0.007097838,-0.024037403,-0.078434605,-0.015682951,0.031362216,-0.01502747,-0.007958884,0.011592419,-0.064624479,0.02033099,-0.034526666,0.017150749,-0.065225554,-0.040019739,-0.11684947,1.263908535,2.456590378,-5.793194141,-4.276433571,-6.845551781,-7.625619507000001,-4.064447113,-6.153918732,-4.9400459969999995,-0.9730085940000001,-6.140216827392578,-6.355471134185791,-5.508664131164551,-6.162938594818115,-5.778977394104004 -4629,4629,T267P,0.02059026,-0.002914247,-0.016694784,-0.00839914,-0.002425347,-0.009897896,0.015271322,0.025909197999999998,0.018311978,-0.035202189,0.029373696,-0.021112693999999998,-0.012276873,-0.031162145,0.014363865,-0.030052357999999998,0.025201665,1.039176675,2.29824289,-2.859259259,-2.109662727,-1.821796974,-4.480303108,-3.051701172,-2.8328323139999996,-3.0001995339999996,-0.082581052,-3.7017035484313965,-3.491938352584839,-2.7719614505767822,-2.6560840606689453,-2.765810012817383 -4630,4630,T267S,0.025183801000000002,0.011991652,-0.013140151999999999,-0.003108123,0.006278958,0.0035694240000000003,0.015119255,0.035248347,0.026973967999999997,-0.004064626,0.02804793,-0.014941042,-0.011339261000000002,-0.007085261,0.000869015,0.001946152,0.010611764,1.269608364,2.781116593,-0.450986351,0.292122444,-0.36862252799999995,-0.562178108,-0.525494385,-1.0907591779999999,-2.407859556,0.795068914,-2.6500017642974854,-2.2724671363830566,-3.087902545928955,-2.995427131652832,-2.1268203258514404 -4631,4631,T267R,0.02113183,-0.012404533,-0.046325991,-0.005726378000000001,-0.101628915,-0.012564825,0.017752558999999998,0.024511099999999997,0.047787156,-0.056531787,0.031722722,-0.038460142,-0.054191839000000006,-0.028401947,0.016949191000000002,-0.092651755,-0.110606074,1.38287457,2.312930052,-6.026580502000001,-4.9451852039999995,-6.508542847,-7.726665702999999,-4.9833727869999995,-5.969135971,-5.377578659,-1.235775358,-8.005355834960938,-6.510167598724365,-7.39479923248291,-7.332792282104492,-6.669724464416504 -4632,4632,T267W,-0.016843853,-0.008948143,-0.025229775,-0.028948132999999997,-1.686777913,-0.041581739,-0.025017234,-0.008670470999999999,0.006202142,-0.033081608,0.015185323,-0.031691856000000004,-0.018767693999999998,0.012874781,-0.07077104599999999,-1.562030605,-1.811525221,0.7211428409999999,1.318600446,-10.08778003,-8.461348816000001,-11.17075563,-11.49661557,-9.372375832000001,-9.937804306,-8.526535907000001,-5.501191559,-11.261073112487793,-10.50502872467041,-11.865455627441406,-11.987268447875977,-12.907814025878906 -4633,4633,T267V,0.012456952,-0.026528242,-0.024470423999999998,-0.01012388,-0.11003080400000001,-0.00334005,0.00293946,0.021974444,0.06191740900000001,-0.061753757,0.008697274,-0.018002919,-0.030937927999999996,-0.012071091,-0.008176668,-0.111509717,-0.10855189,1.463126322,2.369827496,-5.8761054260000005,-5.100013054,-5.732343796,-6.966497261000001,-5.742238388,-5.8394346310000005,-5.723408009,-1.898301145,-7.6558332443237305,-7.242345809936523,-6.374429702758789,-7.298807621002197,-7.290043354034424 -4634,4634,T267Y,0.012717865,-0.021391266000000003,-0.054047465,-0.025338292999999998,-1.040756044,0.031263901000000004,0.032958646,-0.007522916,-0.010151669,-0.082301345,0.039518813,-0.046377485,-0.061717445,-0.046798745,-0.003877841,-0.787811555,-1.2937005320000001,1.070974179,1.474675182,-8.932333969,-7.231935088999999,-11.11934265,-9.673723946,-7.599572097999999,-9.037096062,-6.692925279,-3.260841987,-9.780962944030762,-9.069074630737305,-9.422597885131836,-10.589316368103027,-10.721281051635742 -4635,4635,M268A,0.028022633999999998,0.00181098,0.044088028,-0.000479489,-0.68416902,-0.106105774,0.039725257,0.016320011000000002,-0.093096223,0.008390383000000001,-0.004768424,0.018469469,0.069706587,-0.017796991,0.016838014,-0.51010241,-0.85823563,0.713424196,1.4387268619999998,-5.836268771,-4.934040726,-4.700607636,-6.773074318,-7.563693152999999,-5.209928024,-4.415452588,1.80880537,-2.1810779571533203,-5.616009712219238,-1.7311424016952515,-6.118020057678223,-6.581147193908691 -4636,4636,M268C,0.082805197,0.0032241590000000003,0.075770314,0.002473344,-1.6200068,-0.133695215,0.092384275,0.073226119,-0.021193027000000003,-0.008631166,0.015079483000000001,0.042704179,0.108836448,0.050167776,-0.045221088,-1.4417212819999998,-1.7982923180000001,0.7098239120000001,1.325910141,-10.6506174,-10.08426623,-9.269208977,-11.41772983,-11.73278481,-10.74909715,-9.576490197,-7.088049726,-7.995802402496338,-10.797401428222656,-8.736456871032715,-11.55102825164795,-12.745970726013184 -4637,4637,M268E,-0.025403508999999998,-0.01330414,0.018856714,-0.022577656,-1.7215773509999999,-0.107603036,-0.030769456,-0.020037561000000002,-0.033942224,0.040645152999999996,-0.067253432,-0.001750609,0.039464036,-0.006397233,-0.038758078,-1.3571262169999998,-2.086028484,0.74592107,1.333068599,-8.965994157,-8.873480026000001,-7.351934868,-9.794858421,-10.02484447,-8.784852997,-4.512979099,0.743119368,-2.497602939605713,-7.8228044509887695,-3.378335475921631,-8.185229301452637,-7.346560955047607 -4638,4638,M268D,0.049559694,0.028195345,0.07424284,-0.004221616,-1.304387473,-0.136454111,0.032070072000000005,0.067049315,-0.012517559,0.049534085,0.006856605,0.011596012,0.136889667,-0.003517083,-0.004926148,-1.31264356,-1.2961313859999999,0.6831222509999999,1.329731004,-8.655913069,-8.121978897,-8.318828987,-9.431975624,-9.434560875,-7.972220963,-3.985179467,0.916457321,-3.28732967376709,-8.472679138183594,-4.155989646911621,-8.76137638092041,-7.9062957763671875 -4639,4639,M268G,0.02292139,0.0193231,0.068683225,0.010629656000000001,-1.144386625,-0.102823661,0.029319029,0.016523751,-0.062661534,0.047815919000000005,-0.00916972,0.047167943,0.090198506,0.005485635,0.015773676,-0.828937425,-1.459835824,0.69215041,1.372410614,-8.51344326,-8.118465034,-8.056979355,-8.565453255,-9.500549026,-8.32576963,-5.054692613,-0.283474921,-4.852257251739502,-7.3092241287231445,-4.470356464385986,-7.123844623565674,-8.896438598632812 -4640,4640,M268F,0.033353528,-0.062578457,0.014290657,-0.04316767,-0.117011117,-0.026667793,0.063537845,0.00316921,-0.083314192,-0.064973928,-0.060182985999999994,-0.032043969,0.060625282,-0.06586419,-0.020471148999999998,-0.089679706,-0.144342528,1.498346185,2.484717432,-2.261966063,-2.458199707,-0.469075829,-2.795057747,-2.072433563,-3.5150634689999998,-3.4209918530000003,0.0177629,-2.0348682403564453,-3.58687686920166,-3.6807193756103516,-4.365079879760742,-6.988196849822998 -4641,4641,M268I,-0.001496065,0.057875014,0.090556975,0.056882353,-0.068482321,0.029583121,0.010712103999999998,-0.013704233,-0.085637899,0.10055143400000001,0.015198594,0.077835663,0.103278286,0.087481288,0.026283417000000003,-0.047065109,-0.08989953199999999,1.28675207,2.551786355,-2.401178044,-3.032053986,-1.9335611190000002,-2.155156891,-2.583850685,-2.30126754,-3.51199769,-0.44261181200000005,-3.1821670532226562,-4.3988494873046875,-2.7902379035949707,-5.174432754516602,-4.095500946044922 -4642,4642,M268H,0.038575572,0.008781273000000001,0.046621277999999995,0.001992934,-0.644612417,-0.131856989,0.052765327,0.024385817,-0.063784701,0.00374099,0.013821555,0.0015921820000000001,0.091650374,0.003808396,0.000177472,-0.499021861,-0.790202973,1.3954915540000001,1.773955546,-10.43987309,-11.12247461,-7.735003464,-11.63664337,-10.810512300000001,-10.8947317,-6.719768196,-1.190047857,-4.270560264587402,-6.805161476135254,-5.507152080535889,-7.821269989013672,-8.601096153259277 -4643,4643,M268K,0.006216201,0.031239483,0.05780349,0.013144583,-1.519471323,-0.109617614,0.010645461,0.00178694,-0.06570203,0.048069312999999995,0.014409653,0.057849892,0.057757087,0.058045482999999995,-0.031756318,-1.348765419,-1.690177227,0.574288409,1.32060653,-7.917690201,-6.747980277999999,-6.907358742,-8.826274437,-9.495972252,-7.610865295,-4.864241378,-0.8899661329999999,-4.110294342041016,-7.847923278808594,-5.4388041496276855,-8.063863754272461,-8.553390502929688 -4644,4644,M268L,0.014769506000000002,0.016643451,0.053684337,-0.0026884490000000003,-0.078608888,-0.023333704,0.033846215,-0.004307203,-0.065944611,0.037797356000000004,-0.004510455,0.01350615,0.093862524,0.009980349,-0.015357246000000001,-0.058765038,-0.098452737,1.35503312,2.454176044,-1.7229785130000002,-1.94728965,-1.16584848,-1.469435661,-2.635960495,-1.396358276,-2.3350306069999998,0.48019009700000004,-2.3962879180908203,-1.8251338005065918,-3.034456729888916,-4.18803071975708,-3.9638617038726807 -4645,4645,M268N,0.015316806,0.008046075,0.03604879,-0.017395317,-0.97278755,-0.059982500999999994,0.039555816,-0.008922204,-0.049154338,0.060901660999999996,-0.044809510999999996,0.05492667,0.017170908999999998,0.04380541599999999,-0.07859605,-0.686175663,-1.259399436,0.594349228,1.376528205,-9.497814194,-8.954752563,-8.446674973,-9.469679176,-11.07690672,-9.541057533,-5.6883705739999995,0.19122663899999998,-4.6225996017456055,-7.905562400817871,-4.589149475097656,-7.337897777557373,-8.079556465148926 -4646,4646,M268Q,0.0066756409999999995,0.011014373999999999,0.040575623,0.010439831,-0.5881475079999999,-0.090680076,0.015438134,-0.002086852,-0.035106212000000005,0.021182521,0.000846226,0.007162203000000001,0.073989042,0.03027648,-0.009396818000000001,-0.408099754,-0.768195262,0.944328774,1.56916387,-9.022070648,-8.198333984,-7.170684196,-10.14937446,-10.37732929,-9.21463131,-5.471202571,0.40354730299999997,-3.492154598236084,-6.272123336791992,-4.2850470542907715,-6.673290729522705,-7.621438503265381 -4647,4647,M268P,-0.025339066,0.012548151,0.053719085,-0.010209923000000001,-0.665290805,-0.09524845800000001,-0.021348835,-0.029329297,-0.07354654299999999,0.031901041,-0.006804739000000001,0.045670109,0.061768061,-0.005047329000000001,-0.015372516999999999,-0.474359695,-0.856221915,1.137036883,1.6208211680000002,-5.893184334,-4.703662521,-5.119691834,-6.555620514,-6.951009552,-6.135937247999999,-4.647321825,-0.227785848,-2.629256248474121,-6.471714973449707,-2.1575160026550293,-6.619208335876465,-7.444441795349121 -4648,4648,M268S,0.027183596,0.004268478,0.052981494000000004,0.003781332,-0.823971461,-0.100674754,0.052093667,0.002273525,-0.05521974599999999,0.012769488,-0.004232532,0.015448443000000001,0.090514545,0.022158779,-0.014596116000000001,-0.645963591,-1.00197933,0.657247371,1.39387013,-6.548250322,-5.0516698380000005,-5.004062248,-7.253809813999999,-7.957999001,-7.473710709,-4.237564153,-0.130169311,-3.875657558441162,-6.568563461303711,-3.26617431640625,-6.84293794631958,-7.264161109924316 -4649,4649,M268R,0.017703935,0.000784066,0.041178194,-0.021773518,-1.4262330859999999,-0.10689817,0.034836046,0.000571824,-0.06306885200000001,0.012880243000000001,-0.011312112,0.016945289,0.065411099,-0.026772577000000002,-0.016774458,-1.244938619,-1.6075275519999999,0.9268493,1.36305355,-8.132532494,-6.481900252999999,-6.266915627,-9.116715881000001,-9.923524857,-8.87360585,-4.4124972069999995,0.024086307,-4.2723870277404785,-6.585251808166504,-5.309597969055176,-7.698712348937988,-8.616454124450684 -4650,4650,M268T,0.007653910999999999,0.012619863,0.049142689,-0.004214333,-0.601201794,-0.08482651199999999,0.020362385,-0.005054564,-0.046460419,0.037361978,-0.012122253000000001,0.032333621,0.065951757,-0.01256315,0.004134484,-0.421223316,-0.781180271,0.914113788,1.554296162,-6.178755037,-5.8517212910000005,-4.862786659,-6.981656029,-7.348989242999999,-5.8486219639999995,-5.096371896,0.040626767,-3.8988308906555176,-6.873805046081543,-3.3404836654663086,-6.416498184204102,-6.399064064025879 -4651,4651,M268W,-0.004153718,0.031237211,0.04557365,0.000706916,-0.249969002,-0.011602582,-0.032244917000000005,0.023937481,-0.083850833,0.057575757000000005,0.0048986640000000005,0.01452416,0.076623139,0.015729777,-0.014315946000000001,-0.178129622,-0.321808382,1.524120394,2.287724827,-8.215593687,-8.339175888,-6.715449233999999,-8.196621863999999,-9.488346466,-8.338374985,-7.7199340770000004,-4.209013455,-4.587792873382568,-7.498270034790039,-7.172069549560547,-8.580968856811523,-10.013439178466797 -4652,4652,M268V,0.042375064000000004,-0.00012037799999999999,0.048121945,0.017640563999999997,-0.21220918,-0.066274742,0.063631004,0.021119122999999997,-0.034453793999999996,0.01527118,-0.015511935,0.009329466,0.086914424,-0.0020465410000000002,0.037327668,-0.15498900000000002,-0.269429359,1.249041308,2.076863988,-3.574595856,-3.953622078,-2.307736961,-3.5189147569999997,-3.984887398,-4.107818085,-4.599357159,-0.23475161,-3.3419952392578125,-5.54280948638916,-3.0637874603271484,-6.221626281738281,-5.419145584106445 -4653,4653,M268Y,-0.030099196,-0.002161302,0.00696042,-0.060742937999999996,-0.670814771,-0.053358800000000005,-0.029492392000000003,-0.030705998999999998,-0.037330952,0.028046725,-0.032369327999999996,-0.01087392,0.024794759,-0.078375085,-0.04311079,-0.482572404,-0.8590571379999999,1.5026274659999999,1.8495217030000002,-7.026033900000001,-7.653235947000001,-5.527852211,-6.993723747000001,-6.635228119,-8.320129478,-6.132814914,-1.142366709,-3.319760799407959,-6.482877731323242,-5.427945137023926,-6.96823787689209,-8.712608337402344 -4654,4654,D269A,0.051102666,-0.035273753,0.036073834,0.0034933259999999997,-0.017503169,-0.003989707,0.057147643,0.045057689000000005,-0.05294694900000001,-0.033426776,-0.03712073,0.019110876000000002,0.05303679099999999,0.026735019,-0.019748368,-0.027523005,-0.007483332,1.335942157,2.579761923,-0.674442964,-1.014336182,-0.404730972,-1.200135452,-0.49308329799999995,-0.259928917,-2.9644033110000003,0.657361391,-3.7188265323638916,-3.7356746196746826,-3.72938871383667,-2.5720996856689453,-4.59337043762207 -4655,4655,D269C,-0.030770863,-0.047987552,0.035372827999999995,0.012540753,-0.248746876,-0.044170713,-0.06494373,0.003402005,-0.023248827000000003,-0.016819614,-0.07915549,0.032071743,0.038673912000000005,0.053870392999999996,-0.028788888,-0.219037772,-0.27845597899999996,1.15441025,1.9221092380000002,-8.174430284,-8.617481384,-8.296215332000001,-9.277652939,-7.714647437999999,-6.966154327000001,-8.739158639,-7.825748977000001,-11.234567642211914,-11.78222942352295,-13.053462982177734,-11.086423873901367,-14.576407432556152 -4656,4656,D269E,0.069690628,-0.022694297000000002,0.063534603,0.010276244,-0.028764448999999997,0.003450122,0.095048891,0.044332365,-0.005995537,-0.027233043999999998,-0.01815555,0.019180088,0.107889118,0.005166512,0.015385975,-0.051776836,-0.005752062,1.246647087,2.42582167,-0.96290901,-1.5188970259999999,-0.393354507,-1.40404631,-0.484152084,-1.014095123,-2.007282661,0.637694037,-2.8677659034729004,-3.767559766769409,-3.119239330291748,-2.3611841201782227,-3.1642961502075195 -4657,4657,D269G,-0.014087448999999998,-0.047609230999999995,0.025288663,-0.01368996,-0.055161395999999994,-0.036859391,-0.028955372000000004,0.000780474,-0.017765658,-0.014858583,-0.08035987900000001,0.05014948,0.000427846,0.050443311,-0.07782323,-0.039782219,-0.070540572,1.126542494,2.431668703,-3.863792229,-4.5040758819999995,-2.902243027,-4.477942627,-3.418045425,-4.016654182,-3.7127308269999997,-1.053526039,-6.578138828277588,-5.810277938842773,-6.186384677886963,-5.247530937194824,-7.129064559936523 -4658,4658,D269F,-0.009014459,-0.036679361,0.03621572,-0.026963981,-0.12785417400000001,-0.056867935999999994,-0.030690704,0.012661786999999999,-0.0071490419999999995,-0.037827995,-0.035530727000000005,0.072120209,0.000311231,0.008382588,-0.06231054900000001,-0.073383082,-0.182325265,1.381488188,2.474124857,-7.864631913999999,-8.34650367,-8.374730827,-8.992585808,-7.73060006,-5.8787392039999995,-6.210028952999999,-3.0156478669999998,-8.833211898803711,-8.410344123840332,-9.6444091796875,-9.102052688598633,-10.33191204071045 -4659,4659,D269I,0.173859801,-0.014213368999999998,0.018566311000000002,0.016979829,-0.008056493,-0.054091047,0.161908955,0.18581064600000002,0.045683539,-0.10351910199999999,0.07509236400000001,-0.064256383,0.101389005,-0.056088007,0.090047664,-0.10326316199999999,0.087150176,1.490862979,2.350063778,-5.883578241,-6.244813026,-5.8621764910000005,-6.855109688,-5.716116669,-4.739675331,-5.766905226,-2.271021291,-6.505525588989258,-6.856263160705566,-8.277277946472168,-7.007321834564209,-7.9976677894592285 -4660,4660,D269H,-0.046883775999999995,-0.066250988,0.068053543,-0.021062612,-0.07581602,-0.018070605,-0.081046964,-0.012720588,0.043668248,-0.028394626,-0.104107349,0.059739308,0.076367777,0.036635161,-0.078760384,-0.029540275,-0.122091764,1.22273188,2.520490165,-4.60961597,-4.090373688000001,-5.007695686,-5.853297386,-3.8763616180000002,-4.220351471,-5.450312124,-2.08337262,-7.628537178039551,-7.178930282592773,-8.139777183532715,-6.929454803466797,-8.917133331298828 -4661,4661,D269K,-0.099158329,-0.110053949,-0.083752889,-0.122898966,-0.127878216,-0.11162422400000001,-0.142661639,-0.05565501900000001,0.012271235,-0.059174961,-0.160932936,-0.008045898000000001,-0.159459879,-0.104640483,-0.14115744800000002,-0.157230622,-0.098525809,1.456416069,2.23460833,-1.952627034,-2.313077362,-2.2424673999999998,-3.344438171,-1.05825396,-0.804898277,-1.7232706080000002,0.10754752699999999,-5.724298477172852,-6.925811767578125,-6.898411273956299,-5.442331314086914,-7.524635314941406 -4662,4662,D269M,0.043389405,-0.071248708,0.002566298,-0.024322301,-0.063459543,-0.03200592,0.031549753,0.055229057000000005,-0.035757211000000004,-0.07966949200000001,-0.062827923,-0.06523035599999999,0.07036295099999999,-0.06503091,0.016386308,-0.107984804,-0.018934281,1.414112611,2.3879598580000003,-6.734389998999999,-7.187047043,-6.965687141,-7.433446067999999,-6.4877101139999995,-5.598059631,-6.042017246,-3.4163557669999998,-7.55480432510376,-8.341184616088867,-8.867350578308105,-7.682269096374512,-8.660905838012695 -4663,4663,D269L,0.047875269000000005,-0.031406776000000004,0.042570263,0.006769323000000001,-0.07140762,-0.006988763,0.048120807,0.04762973,-0.031450713,-0.008431788,-0.054381764000000006,0.036688985,0.048451540999999994,0.030609887000000002,-0.017071242,-0.089446235,-0.053369004000000005,1.3217134959999999,2.361110558,-5.789163791,-6.351070517999999,-6.112086037,-6.636318169,-5.439526604,-4.406817627,-5.030517318999999,-1.729795671,-5.96484375,-7.1278839111328125,-8.026280403137207,-6.629878044128418,-7.841319561004639 -4664,4664,D269N,0.016199764,-0.005721141999999999,0.08172407,-0.019859105,-0.039656706,-0.014000137,-0.0041564340000000005,0.036555961,-0.050249432999999996,-0.008059304,-0.00338298,0.111476621,0.051971519,0.014113471,-0.053831681,-0.04857385,-0.030739562,1.372238555,2.532056121,-2.615338319,-2.5146450419999997,-2.649364311,-3.3737269519999997,-2.367295242,-2.171660049,-2.759974525,-0.54730329,-6.084763050079346,-5.791520118713379,-6.1406450271606445,-5.674632549285889,-6.474237442016602 -4665,4665,D269Q,0.00181108,-0.040102944,0.024425894,-0.016140259,-0.07497792,-0.111944763,-0.031600861,0.035223021,0.057921743,-0.037712083,-0.042493805,0.0030831770000000003,0.04576861,0.05864754,-0.09092805699999999,-0.069691642,-0.080264197,1.244562121,2.363300113,-2.825870198,-3.597037498,-2.875212326,-3.781540764,-2.413122101,-1.462438301,-3.8200579969999997,-0.8189439620000001,-5.005096435546875,-6.235888481140137,-5.6554107666015625,-4.473514080047607,-6.0660786628723145 -4666,4666,D269P,0.021723585,-0.038386716,0.006374778,-0.011030802,-0.09725395099999999,-0.05058156900000001,0.019002346,0.024444824,-0.042526189000000006,-0.017607266,-0.059166165,0.002257383,0.010492173,0.039616616,-0.06167822,-0.092860079,-0.101647822,1.4304503130000001,2.455656409,-2.6604151469999997,-4.033313049,-2.8951815869999997,-2.771419807,-2.210753395,-1.3914078980000002,-2.893227374,0.77993807,-5.010606288909912,-4.292876243591309,-4.731627464294434,-3.932476282119751,-6.800250053405762 -4667,4667,D269S,-0.01871066,-0.049684078,1.21e-05,0.010309779,-0.041011648,-0.035341633,-0.031269003,-0.006152316,-0.035036898,0.00403087,-0.103399025,0.066390582,-0.066366468,0.071654269,-0.051034710999999996,-0.037176777,-0.044846517999999995,1.3726640069999998,2.687981633,-2.357086189,-3.076577683,-2.187303337,-3.0809495539999996,-2.174569176,-1.266031197,-3.0003469760000003,-0.7918456859999999,-5.578916072845459,-5.074241638183594,-5.364603042602539,-4.77817440032959,-6.518241882324219 -4668,4668,D269R,-0.00517351,-0.056264374000000006,0.009622668000000001,-0.023041055,-0.115253874,-0.040144037,-0.020781741,0.010434721,-0.054668734000000004,-0.034857697,-0.07767105,0.009543546,0.009701789,0.015566232,-0.061648340999999995,-0.102670105,-0.127837643,1.4102138380000002,2.421800229,-3.455981917,-3.6857695689999996,-3.3976728210000005,-4.634147186,-2.9143128739999997,-2.648007133,-4.702547644,-0.971151257,-7.592565536499023,-8.15611457824707,-8.535609245300293,-7.090119361877441,-9.350471496582031 -4669,4669,D269T,0.031119606,-0.043040630999999996,0.039245758,0.011763764,-0.040370777000000004,-0.019499406,0.00569136,0.056547852,-0.047339543,-0.023459409,-0.062621852,0.032858419,0.045633097000000004,0.064554285,-0.041026757999999997,-0.027152246,-0.053589307,1.3964189390000001,2.684515578,-2.429630251,-2.735876694,-2.547397865,-3.380374435,-1.579773285,-1.904728973,-2.8124337789999996,-0.5746494000000001,-5.127581596374512,-5.292929649353027,-5.585249900817871,-4.68910551071167,-6.138944625854492 -4670,4670,D269W,0.014771783,-0.09888849699999999,0.045701301,-0.044088059000000006,-0.17828193,-0.018523331,0.011422298999999999,0.018121267,-0.01534352,-0.070227935,-0.127549059,0.084389903,0.007012698,-0.009831863,-0.078344254,-0.13791394,-0.21864992,1.3617598480000002,2.235593191,-8.125564102,-8.473323181,-8.180314888,-9.229200714,-7.9967837070000005,-6.748198021,-6.860639339,-4.429510195,-11.360734939575195,-11.128289222717285,-11.112251281738281,-10.806894302368164,-12.237759590148926 -4671,4671,D269V,0.0033106340000000002,-0.08435041300000001,0.012678241000000002,-0.046586452,-0.059219047000000004,-0.016439551,0.004220794,0.0024004729999999998,-0.005018627,-0.082364699,-0.086336127,0.00379689,0.021559592000000002,-0.025878517,-0.067294387,-0.076527508,-0.041910586,1.282274329,2.283398773,-3.705761815,-3.718711266,-3.629392029,-4.516423828,-3.7501595689999996,-2.914122383,-4.064445108,-1.005542191,-5.357213020324707,-5.804765701293945,-6.4837727546691895,-5.429704666137695,-6.904703617095947 -4672,4672,D269Y,-0.010307908000000001,-0.11809160699999999,-0.052462603,-0.050583308,-0.12499882699999999,0.020011073,-0.049679065,0.02906325,-0.08767428599999999,-0.09604189099999999,-0.14014132199999998,-0.050340486,-0.05458472,0.037281336,-0.13844795199999999,-0.082701389,-0.167296265,1.356455985,2.37120265,-6.630472472,-6.626988792000001,-8.1744925,-7.925972389,-5.716406578,-4.708502098,-5.608159553999999,-1.965443775,-9.33853816986084,-8.614055633544922,-9.824827194213867,-9.373918533325195,-10.496138572692871 -4673,4673,E270A,0.091651093,-0.023237382,0.037808646,0.197033925,0.078759389,-0.02456431,0.062776848,0.120525337,0.07186695400000001,-0.019212703,-0.02726206,-0.088314115,0.163931407,0.123685134,0.270382716,0.039040369,0.11847840800000001,1.027434188,2.893681162,-2.823240953,-2.524744736,-2.7061158069999998,-3.2582043689999995,-2.889568604,-2.7375712510000003,-4.5319126380000005,0.076322243,-4.982602119445801,-4.845686912536621,-5.661428451538086,-4.183498382568359,-4.127505779266357 -4674,4674,E270C,0.037849531,-0.056735985,-0.034056364,0.101675529,-0.244633761,-0.066169072,0.012326041999999999,0.063373019,0.039927947000000005,-0.055655177,-0.057816793,-0.188727007,0.12061428,-0.00085431,0.204205367,-0.20635210399999998,-0.282915417,1.393059971,2.0837291430000002,-9.484078505,-9.272044418,-9.688048126,-10.96170597,-8.699922858999999,-8.79867115,-8.105426653,-5.811157538,-10.86005973815918,-12.99992847442627,-12.557247161865234,-10.569517135620117,-12.357270240783691 -4675,4675,E270D,0.071480486,0.049407767000000005,0.113168499,0.1973616,0.111175353,-0.067214884,0.082137801,0.06082317,0.07058107400000001,-0.035874257,0.134689791,0.009029317,0.217307681,0.115000214,0.279722986,0.068048738,0.154301968,1.15557715,2.906122685,-2.8667482860000004,-2.892088852,-2.18089743,-3.552958504,-2.8407515560000003,-2.86704509,-3.390357855,-0.874838448,-4.648780822753906,-4.190272331237793,-5.01494026184082,-4.738347053527832,-4.621830463409424 -4676,4676,E270G,0.150667204,-0.00119775,-0.039345302,0.07391824799999999,-0.5922990570000001,-0.101817035,0.136451215,0.164883193,0.10003819800000001,-0.023840909,0.02144541,-0.11965314,0.040962537,0.04441914,0.103417355,-0.386548025,-0.7980500890000001,1.055090209,1.6486648680000002,-6.127391969,-7.1113998789999995,-5.2690396580000005,-7.200362114,-4.834701126000001,-6.2214570689999995,-4.662094777,-1.391147713,-6.982048511505127,-7.067263126373291,-7.579864978790283,-4.919046401977539,-7.668841361999512 -4677,4677,E270F,0.013703646000000002,-0.049621599,-0.163358752,-0.05995315,-0.148212625,-0.178001288,0.022748066,0.004659225,-0.044582132999999996,-0.025632138,-0.07361106,-0.388180171,0.061462668,-0.179904229,0.05999793,-0.22230807800000002,-0.074117172,1.800293665,2.319079553,-8.87487885,-7.947089523,-8.940777435,-11.76601304,-8.654778038,-7.065736214,-5.558665512999999,-3.4801372880000003,-7.686550140380859,-9.736529350280762,-7.974583625793457,-8.565927505493164,-8.98415756225586 -4678,4678,E270I,0.08447222199999999,0.019155818999999998,0.028798893,0.198463243,-0.067328252,-0.012445091,0.057431928,0.111512515,-0.027152246,-0.217605783,0.25591742100000003,-0.206125965,0.26372375,-0.106994492,0.503920978,-0.056644288,-0.078012216,1.387026486,2.343490509,-4.981078366,-4.884583359,-5.49786544,-4.932682381,-4.579838165,-5.010422485,-4.686844549,-2.440363347,-6.386568546295166,-7.292294979095459,-7.9851298332214355,-6.953739166259766,-4.968279838562012 -4679,4679,E270H,0.15592124400000001,0.003732139,-0.038773427,0.08625919300000001,-0.007309004,-0.102296379,0.154761347,0.157081141,0.09828654199999999,-0.11270428,0.120168557,-0.185725218,0.108178365,-0.101708896,0.274227282,-0.08027919,0.065661182,1.356222896,2.244818374,-6.934721574,-6.795305717000001,-7.141623245,-8.805610512000001,-7.277054512,-4.654013886,-5.926598518,-2.242733038,-6.950818061828613,-8.605201721191406,-7.133340835571289,-6.705373764038086,-7.994378566741943 -4680,4680,E270K,0.080472677,-0.147520202,0.024444241000000002,0.119127625,-0.081976048,-0.23408869399999999,-0.018288786,0.179234139,-0.096910013,-0.261357291,-0.033683113,-0.077942174,0.12683065599999999,-0.045757491,0.284012741,0.0020152910000000002,-0.165967386,1.312050494,2.647915167,-4.592292458,-5.255593567,-4.579212524,-5.390334212999999,-3.9316270980000003,-3.804694885,-4.937800765,-1.52398333,-6.473240852355957,-7.391922950744629,-7.700606822967529,-5.3034210205078125,-6.726975440979004 -4681,4681,E270M,0.11793053699999999,-0.17935717199999998,-0.079502447,-0.049851457,-0.310200101,0.007087503,0.053797644000000006,0.182063429,0.164810249,-0.377522103,0.01880776,-0.38377105200000006,0.224766159,-0.159700843,0.05999793,-0.257152258,-0.363247944,2.049690423,2.5056082490000002,-5.316188264,-4.991301628,-6.156343216000001,-5.385351654,-5.576166893,-4.471777931,-4.894227677,-3.205877278,-7.648123741149902,-7.9750237464904785,-8.80605697631836,-6.538029670715332,-6.500672340393066 -4682,4682,E270L,0.108808338,-0.033873145,0.006217116,0.10767846800000001,-0.017462942,0.071375882,0.115369945,0.10224673,0.010995383999999999,-0.08473608099999999,0.016989791,-0.157637682,0.170071914,-0.038115748,0.253472684,-0.115562346,0.08063646299999999,1.310213176,2.2361428340000002,-4.230964418,-3.466830322,-5.8588928760000005,-4.616414719,-3.9792983019999997,-3.233385872,-4.340833464,-2.326500595,-5.855233669281006,-7.322046279907227,-7.403547286987305,-5.992478370666504,-5.250179767608643 -4683,4683,E270N,-0.021896967000000003,-0.214591041,-0.061553189,-0.031661058,-0.065881175,-0.047692317000000005,-0.009936710999999999,-0.033857222,0.16633142199999998,-0.081631747,-0.34755033399999996,-0.16706194300000002,0.043955565,0.057008267,-0.12033038199999999,-0.090130932,-0.041631417999999996,1.089609965,2.12619429,-5.678670201,-5.481844497999999,-6.118224297,-6.639164665,-4.613272736,-5.54084481,-4.832668534,-2.181981968,-7.079089164733887,-7.365019798278809,-6.728976249694824,-5.899815559387207,-6.321652412414551 -4684,4684,E270Q,0.32779339,-0.18041901800000001,-0.014080337,0.030100792999999997,0.06728105200000001,-0.08403233,0.294221028,0.36136575200000004,0.246672333,-0.605295835,0.24445779899999998,-0.286155443,0.257994769,-0.149235409,0.209436994,-0.17806645100000001,0.312628554,1.693481663,2.304284563,-1.7611255680000002,-1.969540421,-2.7589512939999996,-1.398242294,-1.996290474,-0.682603355,-2.2399601959999997,-0.876759223,-5.120512008666992,-5.938946723937988,-5.925619125366211,-3.6669631004333496,-4.983671188354492 -4685,4685,E270P,0.029197373,-0.023891091,-0.056959565999999996,-1.340285675,-1.986815688,-0.10611909300000001,0.0013974679999999998,0.056997277,0.00604596,-0.051357814,0.003575633,-0.141432914,0.027513782999999997,-0.9133783240000001,-1.767193025,-1.849068256,-2.12456312,2.471440835,1.77898438,-7.581453,-7.904668289,-7.333040168999999,-8.63092318,-7.2162341770000005,-6.822399185,-4.9048080810000005,-1.325246367,-6.5017170906066895,-8.045116424560547,-8.72655200958252,-7.842665672302246,-7.531490325927734 -4686,4686,E270S,0.043260195,-0.017773047,0.004583866,0.101468164,-0.039686684,-0.035918412000000004,0.041107391,0.045412999,0.06366908,-0.037167325,0.001621232,-0.08984139699999999,0.099009129,0.063085908,0.139850419,-0.047672492999999996,-0.031700874,1.285933114,2.532038708,-5.68598898,-5.799924248,-5.571584763,-6.862362778,-5.055758064,-5.140315048,-4.731199162,-1.415635969,-6.293975830078125,-6.919778347015381,-7.386909008026123,-5.692434310913086,-5.829343795776367 -4687,4687,E270R,0.049859271,-0.076785835,-0.09640856800000001,0.05169493,-0.210595029,-0.041734467000000004,0.011364338,0.088354204,0.021002947,-0.13743129,-0.016140379,-0.148494769,-0.044322367,-0.044307424000000005,0.147697284,-0.301909135,-0.11928092300000001,1.558660261,2.091780322,-4.994813402,-4.893377205,-5.176808868,-5.979057739,-5.441427979,-3.483395218,-4.115780973,-0.8618158570000001,-7.494047164916992,-9.074313163757324,-9.279915809631348,-6.494939804077148,-8.056051254272461 -4688,4688,E270T,0.141304054,0.037794904,0.002968223,0.150036634,0.0043225270000000005,-0.046202888,0.120072924,0.162535184,-0.010219165,0.022211277999999997,0.05337853,-0.113328715,0.11926516,0.07250635799999999,0.22756691,-0.011290176,0.019935229,1.243936137,2.703743926,-2.810873518,-2.093369499,-3.8940145339999996,-2.8390390930000002,-2.733845497,-2.494098969,-3.495288191,-0.8261494490000001,-5.739703178405762,-6.258040904998779,-6.577801704406738,-5.426089286804199,-3.0865111351013184 -4689,4689,E270W,-0.040624409,0.042032106,-0.053543355,0.099084282,-0.625633446,0.110624469,-0.060145709000000006,-0.021103108,0.10011515300000001,0.100018557,-0.015954346,0.079855093,-0.186941802,0.194574665,0.003593898,-0.509474865,-0.741792027,0.410732081,1.3730191980000002,-9.305013268,-9.699569504,-9.118012726,-11.14501562,-8.817969315,-7.744499176000001,-5.390238897000001,-3.1679026410000004,-9.290140151977539,-10.647859573364258,-9.393953323364258,-9.663496017456055,-11.451423645019531 -4690,4690,E270V,0.055540807000000005,-0.048362614000000005,-0.038161704,0.11561983599999999,-0.007478681,-0.03275788,0.001353778,0.109727835,0.009870754,-0.125760486,0.029035257999999998,-0.134484055,0.058160647999999995,-0.006217375,0.237457046,-0.116674496,0.101717134,1.417640351,2.2866004980000003,-2.823124092,-2.185381927,-2.8509802860000004,-2.480425499,-3.1088026660000003,-3.490030083,-4.565133199,-1.3447161890000001,-5.825024604797363,-6.350766181945801,-6.545424461364746,-5.583588600158691,-4.073459625244141 -4691,4691,E270Y,0.114330944,-0.128712801,0.012145378,0.064690812,-0.157183129,-0.127516339,0.087655911,0.141005977,-0.083546051,-0.031204377999999998,-0.226221223,-0.169022643,0.193313399,0.050248682999999995,0.07913294,-0.16106784,-0.15329841800000002,1.250853078,2.066913331,-8.107741341,-8.404937721,-8.348278792999999,-11.12999238,-7.442288382999999,-5.213209427,-4.485849636,-1.06583056,-7.427992343902588,-9.494851112365723,-5.822352886199951,-8.370261192321777,-9.309577941894531 -4692,4692,R271A,-0.005525891999999999,0.033199527,0.039465529,0.021896495,-0.226637311,-0.011157455,0.00059959,-0.011651373000000001,-0.020114826000000002,0.078244238,-0.011845185,0.041577429,0.037353628,0.029349572999999997,0.014443416,-0.138509057,-0.314765564,1.338780602,2.222551131,-5.5785108260000005,-4.195139191,-7.7776217270000005,-5.702666344,-5.348579155,-4.868547714,-4.101888514,-0.000559988,-7.865306377410889,-10.764303207397461,-7.761660575866699,-8.21865177154541,-7.933229446411133 -4693,4693,R271C,-0.03578944,-0.010230463,0.012696216000000001,-0.012113344,-0.16233376900000002,0.004289188,-0.0711741,-0.000404779,0.016428191,0.014550425,-0.035011351,0.04657366,-0.021181228,0.02428035,-0.048507037999999995,-0.08897446199999999,-0.235693076,1.264454929,2.305016571,-7.358436671000001,-8.264018593,-7.716170105,-7.453663033,-8.07056739,-5.287764236,-5.315231642,-3.9215264789999997,-9.881985664367676,-10.695690155029297,-10.880866050720215,-9.537283897399902,-9.091202735900879 -4694,4694,R271E,-0.05301536900000001,0.027476642000000003,0.031208071,-0.429989016,-2.389584217,-0.067555845,-0.058059260999999994,-0.047971476,0.02274703,0.070172473,-0.01521919,0.061428715,0.000987427,-0.00868117,-0.851296862,-1.667864802,-3.111303631,0.698024895,1.3131915490000001,-10.45165013,-11.05660411,-10.06568335,-11.00951213,-12.57478398,-7.551667084,-4.909823619,-3.039044066,-12.142427444458008,-13.065546989440918,-11.186312675476074,-10.721385955810547,-11.378727912902832 -4695,4695,R271D,0.065735182,0.082801283,0.068888275,0.08581628699999999,-1.609124252,-0.091853302,0.06689617099999999,0.064574193,-0.027707467000000003,0.087219053,0.078383513,0.085752177,0.052024372,0.12115990300000001,0.050472671,-1.341387684,-1.87686082,0.49934165799999997,1.315851796,-11.19416054,-9.769874512000001,-11.71138618,-11.72797646,-12.31688966,-10.44467587,-3.782286027,-0.628842501,-11.720653533935547,-13.674945831298828,-9.058998107910156,-11.600727081298828,-11.897955894470215 -4696,4696,R271G,0.007470401999999999,0.01804001,0.036807649,0.013305932,-0.9991883490000001,-0.067928491,0.009629181,0.0053116230000000006,0.024342446,0.022514778,0.013565241,0.033601465,0.040013832,0.0066233590000000005,0.019988505,-0.7822028940000001,-1.216173803,0.8558167990000001,1.412696736,-9.358883806,-8.851324371,-13.61061343,-9.213291161,-8.610203346,-6.508986717000001,-4.607707355,-0.788220178,-9.668977737426758,-10.692849159240723,-9.758767127990723,-9.981002807617188,-10.120186805725098 -4697,4697,R271F,0.103431544,0.074901741,0.091394574,-1.05918513,-1.988937185,-0.103093911,0.120605407,0.08625768,-0.072476489,0.045197593,0.10460588800000001,0.052287507000000004,0.13050164,-0.742641368,-1.3757288909999998,-1.8076780909999999,-2.170196278,2.021030271,1.5441796069999998,-7.890401495,-9.506108986000001,-7.658956085,-5.69568721,-9.64809304,-6.943162155,-5.025148263,-3.0651027330000002,-11.00831127166748,-13.124126434326172,-10.488846778869629,-11.184850692749023,-9.630083084106445 -4698,4698,R271I,0.010065736,-0.078285532,-0.034646696,-0.07030737299999999,-0.15856105,-0.05254426400000001,0.032137289,-0.012005817,0.007689382,-0.125794643,-0.03077642,-0.053362808,-0.015930583,-0.081459925,-0.059154820999999996,-0.131920975,-0.185201124,1.502699513,2.291849633,-5.916934647000001,-7.631395226,-6.042563309,-5.947433205,-5.631646568,-4.331634926,-4.7849538339999995,-2.92474801,-8.474174499511719,-11.554230690002441,-9.308673858642578,-8.239250183105469,-8.229387283325195 -4699,4699,R271H,-0.053557452,0.040878127,0.000275945,0.0034273520000000003,-1.350593911,0.08258908599999999,-0.042915865,-0.064199038,-0.010769301,0.085509838,-0.0037535840000000003,0.078492597,-0.077940708,0.038545243,-0.031690539,-1.1186740929999999,-1.5825137280000001,0.603186059,1.334859372,-7.503212657000001,-8.513963829,-7.804603531000001,-6.758643509,-8.311483719,-6.127368698,-4.790249114,-3.254757586,-9.517820358276367,-9.343243598937988,-7.899800777435303,-9.135144233703613,-7.251948356628418 -4700,4700,R271K,-0.10971967099999999,-0.047148928,-0.035107645,-0.066985803,-0.10937738699999999,-0.022709347999999997,-0.178199868,-0.041239473,-0.020436185,-0.00192166,-0.092376195,-0.025848002000000002,-0.044367287000000005,-0.073026757,-0.060944847999999996,-0.050843892,-0.16791088199999998,1.5464736069999998,2.938183126,-6.330341576,-6.112701675,-9.364824287000001,-5.297240669,-5.855620087,-5.021321159,-4.247444078,-3.3682145269999997,-6.909173488616943,-7.819004058837891,-7.621716499328613,-6.679243087768555,-5.215455532073975 -4701,4701,R271M,0.076466785,0.038253897,0.07728792,0.045271474000000006,-0.04327186,0.040726457,0.07158471799999999,0.081348851,-0.015404123999999998,0.060897499,0.015610295,0.062344777000000004,0.09223106199999999,0.038917537,0.051625410999999996,-0.003208796,-0.08333492299999999,1.287604928,2.657464261,-7.114774141,-8.163379059,-8.568783867,-6.822238014,-6.738262436,-5.281207329,-6.0193609189999995,-4.424314058,-9.453124046325684,-11.451313018798828,-10.097681045532227,-8.781026840209961,-8.423635482788086 -4702,4702,R271L,0.026058122000000003,0.018060137,0.050181815,0.025077868,-0.0015712579999999999,-0.029165316,0.007923366,0.044192877,0.005769753000000001,0.010538563,0.025581711,0.025023446,0.075340183,0.008441458,0.041714278,0.000986355,-0.00412887,1.116072357,2.504805661,-1.7997309769999998,-2.0515470430000002,-2.396899033,-1.882192764,-1.6268643040000001,-1.041151741,-1.72088234,-2.309896272,-7.787140369415283,-10.996478080749512,-7.751307010650635,-8.04067325592041,-6.5669145584106445 -4703,4703,R271N,0.012852291000000002,-0.038103534,0.009957718,0.04613864,-0.209096776,0.019999018,-0.08383116,0.10953574199999999,-0.046271186,0.018687419,-0.094894486,-0.030394409,0.050309845,-0.006356591,0.098633871,-0.14494547,-0.273248082,1.325286068,2.206595872,-9.632101596,-9.66559713,-10.32803674,-9.839833244,-9.728282806000001,-8.598758057000001,-4.211968324,-1.097126517,-8.47447395324707,-11.065616607666016,-7.678351402282715,-8.475425720214844,-7.341692924499512 -4704,4704,R271Q,-0.028169395,-0.015179038999999998,-0.009641953,0.050044658,-0.152919851,-0.050078149,-0.063873268,0.007534479,-0.075424159,-0.001365941,-0.028992137,-0.010790876000000001,-0.00849303,0.036075886,0.06401343,-0.106998744,-0.19884095699999998,1.266986491,2.216815181,-6.820826326000001,-7.568268387000001,-8.348463371,-7.45922242,-6.076279396,-4.651898056,-3.495614264,-1.9348413340000001,-8.279609680175781,-9.26803207397461,-8.947138786315918,-7.504489898681641,-6.9018025398254395 -4705,4705,R271P,-0.012033445,0.029142241,0.03268523,-0.22354957600000003,-1.75957902,-0.082940006,-0.011948516999999999,-0.012118371999999999,-0.026342761,0.048983174000000004,0.009301308000000001,0.020216348000000002,0.045154112,-0.020126558,-0.426972594,-1.667864802,-1.851293237,0.708691427,1.313370867,-10.06670939,-11.08811894,-11.11399947,-9.75744091,-9.783883804,-8.590103844,-5.584129107000001,-3.9628908610000004,-12.594778060913086,-12.64685344696045,-8.712321281433105,-11.550797462463379,-13.56453800201416 -4706,4706,R271S,0.012450006999999999,-0.0061822430000000005,0.018134179,0.026403676,-0.48528999999999994,-0.063183739,0.008724085999999999,0.016175928,-0.048366552,-0.001365941,-0.010998543999999999,-0.020953105,0.057221462,-0.007062459,0.05986981,-0.38183499,-0.58874501,1.008784361,1.620262593,-5.116396861,-4.569901917,-6.161299492,-5.654759491,-5.091296501,-4.104726906000001,-3.35408581,-1.6979162069999998,-9.415990829467773,-10.406418800354004,-8.732675552368164,-9.039708137512207,-8.271394729614258 -4707,4707,R271T,0.004298607,0.006811419,-0.001557805,-0.046779843,-0.219194195,-0.06186127,-0.02900926,0.037606473,-0.018951604,0.032929159,-0.019306321,0.024165977999999998,-0.027281588,-0.0039083040000000005,-0.08965138199999999,-0.163111481,-0.275276908,1.476887223,2.27405069,-6.450218137,-7.0046626210000005,-6.54497789,-7.960066512999999,-5.270193358999999,-5.4711903,-5.047270664,-2.260794497,-8.523760795593262,-11.243785858154297,-9.428791046142578,-8.608574867248535,-8.334854125976562 -4708,4708,R271W,-0.024721688,0.00600562,-0.031350643,-1.4902387469999998,-1.8522165000000002,-0.19887945699999998,-0.04065369,-0.008789686,-0.060385395,0.054957430999999994,-0.042946192,0.059190133,-0.121891418,-1.319147255,-1.661330239,-1.8105073809999999,-1.893925619,3.212294552,2.370714614,-10.36453822,-10.84102312,-10.85495948,-10.09110312,-11.12797205,-8.907633347,-7.571739833,-5.997125433,-9.851473808288574,-11.41332721710205,-12.709007263183594,-11.543575286865234,-10.726096153259277 -4709,4709,R271V,-0.027211632000000003,-0.005220443,-0.007197276,0.019706283999999998,-0.32337525300000003,-0.068569499,-0.049306079,-0.005117185,0.043408853,0.0032368920000000003,-0.013677778,-0.001679181,-0.012715371000000001,0.022568982999999997,0.016843585,-0.188333885,-0.45841662,1.3659525680000002,2.140208431,-5.672000456,-6.896708817,-5.920889824,-6.075924132999999,-5.544536858,-3.92194265,-5.1517295569999995,-1.7562200209999999,-8.270467758178711,-11.30856704711914,-8.257110595703125,-8.059427261352539,-8.926742553710938 -4710,4710,R271Y,-0.044216372000000004,-0.021677394,0.0011154910000000001,-1.608765727,-1.8952975669999998,-0.11574367199999999,-0.082757017,-0.005675726,0.021145365,-0.012310063999999999,-0.031044724,0.000626893,0.001604089,-1.505728872,-1.7118025819999998,-2.109438607,-1.681156527,1.112417458,0.7526295209999999,-11.42812937,-14.21516967,-12.51848643,-9.646871192999999,-12.10104384,-8.659075706,-6.838377007,-4.80878227,-10.17951774597168,-11.990473747253418,-10.394647598266602,-10.950501441955566,-9.446558952331543 -4711,4711,N272A,-0.003206595,0.037253148,0.025637893999999998,0.018814057,-1.503449934,-0.022050347999999997,0.010751236,-0.017164425,-0.301029996,0.064906639,0.009599657,0.003844158,0.04743163,0.047135961,-0.009507847,-1.47961599,-1.5272838780000002,0.5674433529999999,1.315076988,-8.695042061,-11.65709365,-9.060844521,-7.311714417,-7.767588364,-7.677969353,-6.342204122,-1.157574364,-8.473511695861816,-10.962211608886719,-9.08263874053955,-9.895567893981934,-7.967736721038818 -4712,4712,N272C,0.002339129,0.005863978000000001,-0.009496733,-0.94739273,-2.5359068280000003,0.012800595,0.017364705,-0.012686447,-0.11868978699999999,-0.033517782999999995,0.04524573900000001,-0.058148515,0.03915505,-0.34778253600000003,-1.5470029230000002,-1.7462346219999998,-3.3255790339999995,1.575476365,1.417009194,-11.36816614,-13.24986112,-11.47356143,-9.689869186000001,-11.24678302,-11.18075592,-8.084502696,-2.7652889739999997,-11.163915634155273,-11.278572082519531,-13.151714324951172,-11.352187156677246,-11.915262222290039 -4713,4713,N272E,-0.02002424,-0.015086658000000001,-0.013248158999999999,0.018676339,-1.593646034,-0.009244002,-0.047597420999999994,0.007548941,-0.28061553100000003,-0.007314226,-0.022859089,-0.00418698,-0.022309337000000002,0.014077766,0.023274911000000002,-1.482200926,-1.705091142,0.669185008,1.319673223,-6.596958974,-9.389962364,-5.257612793,-6.011967003,-6.122048187000001,-6.203204521,-6.709522435,0.28369715,-5.2133612632751465,-8.891725540161133,-6.726624488830566,-8.896505355834961,-7.050989151000977 -4714,4714,N272D,0.035129802,0.025773967999999998,0.016224041,0.050486015,-0.07933293,-0.076551483,0.045420222999999996,0.024839381,-0.30209837100000003,0.027903636000000002,0.0236443,0.019622867,0.012825215,0.074494263,0.026477767000000003,-0.079926394,-0.078739465,1.1861484409999998,2.3014651980000003,-4.28526559,-4.910842033,-4.728871506,-3.1103451310000003,-4.544304619,-4.1319646610000005,-3.8191895419999997,0.428275896,-5.157496929168701,-6.077371597290039,-4.145328044891357,-6.610652923583984,-6.808735370635986 -4715,4715,N272G,-0.025887632,0.00344386,-0.021010355,0.029519222,-1.6397913869999998,-0.05851241,-0.04360787,-0.008167393,-0.21641293399999997,0.044679839000000006,-0.03779212,-0.0015138670000000001,-0.040506843,0.06660418,-0.0075657369999999995,-1.507175701,-1.772407073,0.40665314799999996,1.30743929,-9.537358505,-12.81583868,-8.477954238999999,-8.924373802,-9.109165482,-8.359460327,-7.270035837000001,-2.630576544,-9.002412796020508,-8.954512596130371,-8.735937118530273,-10.158553123474121,-8.557512283325195 -4716,4716,N272F,-0.009782553000000001,-0.209506246,-1.595318566,-1.95613561,-2.708675753,0.009510414,0.029612461,-0.049177566,0.267462648,-0.0008150410000000001,-0.41819745,-1.487009134,-1.703627997,-1.839135604,-2.073135616,-2.11939509,-3.2979564160000003,3.7927046160000004,2.2894831719999997,-12.143020300000002,-14.25903537,-12.81730621,-10.62202444,-10.01471681,-13.00201865,-8.506450573,-3.4542252419999997,-11.861902236938477,-15.010843276977539,-11.892976760864258,-12.466143608093262,-10.876457214355469 -4717,4717,N272I,-0.078710899,0.01136864,-0.211616155,-1.5751994619999998,-2.488615886,0.018040012,-0.033071168,-0.124350629,-0.07135590900000001,0.004860737,0.017876542,-0.051104157000000004,-0.37212815299999996,-1.295269961,-1.8551289619999998,-2.221793102,-2.75543867,0.785261256,0.7315211540000001,-12.72876414,-15.03703909,-15.9364978,-12.71388398,-10.22538979,-9.731010071,-8.524841006,-2.0566209140000002,-11.67319107055664,-13.076756477355957,-10.934164047241211,-11.112637519836426,-9.223737716674805 -4718,4718,N272H,-0.012431018,-0.001819407,-0.014202943999999999,-0.45668361700000004,-1.782516552,-0.033910594,-0.001823609,-0.023038426,-0.258442552,0.003956111,-0.007594924,-0.059236292,0.030830405,-0.140416867,-0.7729503670000001,-1.8251260630000001,-1.739907041,1.115358893,1.328920202,-8.365798621,-10.89027876,-9.74103804,-6.736983955,-7.742383437999999,-6.718308914,-6.7472355639999995,-3.013295662,-7.418328285217285,-10.066978454589844,-8.273554801940918,-8.63843822479248,-7.829538822174072 -4719,4719,N272K,-0.053729834000000004,0.027542814,-0.8989110579999999,-1.700728051,-2.7899761439999997,-0.033025672,-0.064105402,-0.043354265999999995,-0.158506084,0.046047448,0.009038179,-0.500343666,-1.29747845,-1.678952705,-1.7225033969999999,-2.331598096,-3.248354192,1.750991385,0.862109468,-8.066130597,-10.49394318,-6.767904617,-8.511230942000001,-8.754548576,-5.803025665,-6.69223581,-1.21357071,-9.19440746307373,-11.004256248474121,-9.1353178024292,-9.012213706970215,-7.582486152648926 -4720,4720,N272M,0.018310811,0.089819225,-0.398696265,-1.692564294,-2.471224247,0.037609638,0.060640152,-0.02401853,-0.386174189,0.099011007,0.080627443,-0.119710496,-0.677682033,-1.563458836,-1.8216697519999998,-2.174711542,-2.7677369510000003,1.228820794,0.756571427,-12.65838694,-15.57863517,-12.26107841,-14.186439000000002,-8.241037299999999,-13.0247448,-8.516267323,-2.799053672,-11.422255516052246,-14.259271621704102,-11.581718444824219,-11.044059753417969,-9.590713500976562 -4721,4721,N272L,-0.045992358,0.00707696,-1.1341726140000001,-1.9886578209999999,-2.585728822,0.047406465999999994,-0.010555025,-0.08142969,-0.134487495,0.028440322999999997,-0.014286403,-0.811309011,-1.457036217,-1.8298648380000002,-2.147450803,-2.378969637,-2.792488006,2.5670800430000003,1.312241153,-12.00424889,-14.75264967,-11.47689108,-13.41644108,-9.604746033,-10.77051659,-7.727594986000001,-2.68970763,-10.935478210449219,-14.794984817504883,-11.088091850280762,-10.486366271972656,-9.883728981018066 -4722,4722,N272Q,-0.021183942,0.007917307,-0.003577385,-0.146648213,-1.972910607,-0.00177953,-0.0022943489999999998,-0.040073535,0.037788561,0.040609966000000004,-0.024775352,-0.00741531,0.000260541,0.03210432,-0.325400746,-1.906069155,-2.039752058,0.7711728840000001,1.304565502,-7.983628147999999,-11.43663958,-6.690371132,-7.491059898,-6.250054497000001,-8.050015633,-6.202955085,-1.394818348,-7.5220489501953125,-11.034159660339355,-8.519043922424316,-8.304971694946289,-7.5932536125183105 -4723,4723,N272P,-0.004011905,-0.28622861,-1.515232467,-2.0454084740000003,-2.7188121639999996,0.003552744,0.016703895,-0.024727705,0.10473535099999999,-0.046707532999999996,-0.525749687,-1.511168549,-1.519296384,-1.926513935,-2.164303013,-2.529797711,-2.907826617,0.67957569,0.037030564,-10.15122138,-11.65572986,-11.56747823,-10.09458411,-9.287427719,-8.150886986,-6.998781227,-2.779802045,-11.897836685180664,-11.81435775756836,-10.448898315429688,-12.665586471557617,-11.681779861450195 -4724,4724,N272S,-0.030252532999999998,0.006409692,-0.010635249,0.015454115,-0.34725384600000003,-0.009283106,-0.025415372000000002,-0.035089694,-0.10398038400000001,0.030051209,-0.017231825,-0.005042993,-0.016227505,0.043702635999999996,-0.012794406999999999,-0.2560418,-0.438465892,0.574596769,1.4552800590000001,-6.064795747000001,-8.025879478,-5.58520314,-5.269724586000001,-6.465253692999999,-4.977917839,-5.12417719,-1.665140482,-8.087852478027344,-8.270771980285645,-7.583583354949951,-8.813770294189453,-6.884881019592285 -4725,4725,N272R,-0.002127541,0.034472437,-0.283097455,-1.6682196130000002,-2.616846506,0.005906766999999999,0.02528944,-0.029544521,-0.290199148,0.056258449,0.012686423999999998,-0.065492516,-0.500702393,-1.406960917,-1.929478309,-2.263726291,-2.96996672,1.141535476,1.839582957,-9.662847717,-12.27937914,-11.24554509,-9.174606445,-9.177989426,-6.436718491000001,-6.549501493999999,-1.1647682129999999,-9.248411178588867,-11.072290420532227,-10.29255199432373,-10.003613471984863,-8.071989059448242 -4726,4726,N272T,0.011714433,0.023926204,0.023053279,0.040536066,-0.465793446,-0.04744578,0.013014786,0.010414079,-0.092754053,0.039889186,0.007963221,0.018384798,0.027721759,0.044706097,0.036366035,-0.365006891,-0.56658,1.894592864,1.422241265,-8.943041521,-10.66430339,-8.499652092,-8.35925164,-8.629180397,-8.562820084,-7.563626579,-2.022385018,-8.767436981201172,-10.220917701721191,-8.556025505065918,-9.118072509765625,-7.020663261413574 -4727,4727,N272W,-0.05497461,-0.333984235,-1.8497057069999998,-2.3175368869999997,-2.795166843,0.007073101,-0.036185193,-0.073764027,-0.158506084,-0.08006738099999999,-0.587901088,-1.830267801,-1.869143613,-1.9927302040000001,-2.64234357,-2.302952914,-3.2873807719999997,2.462272951,1.0421756070000001,-12.0264918,-15.25028069,-12.42730246,-10.732796400000002,-9.337172928,-12.38490652,-8.728449888,-2.860228893,-13.019047737121582,-15.66622543334961,-14.077363014221191,-15.312158584594727,-13.479862213134766 -4728,4728,N272V,-0.006610544,-0.00452383,-1.7800000000000002e-05,-1.210801525,-2.225302873,0.012013821000000001,0.023622985,-0.036844072,-0.196294645,0.028785686,-0.037833345,-0.026556523,0.026520982000000002,-0.771736373,-1.649866676,-2.026441755,-2.42416399,3.881750222,2.131921798,-12.23092758,-13.89471132,-15.56721265,-11.65771252,-9.84912104,-10.18588039,-7.772656755,-2.3576785119999997,-10.99357795715332,-12.310613632202148,-10.699457168579102,-10.723570823669434,-9.149774551391602 -4729,4729,N272Y,-0.019510772,-0.069067065,-1.26830666,-2.0422774180000003,-2.942456395,0.041712855,0.028565985,-0.067587528,-0.298956987,0.013754116,-0.151888246,-1.154319565,-1.382293755,-2.025971137,-2.058583699,-2.482321883,-3.4025909060000004,1.362315305,2.531412538,-10.42520367,-12.76730959,-11.274289900000001,-8.639717743,-9.128848457,-10.31585264,-8.021267678,-2.708028739,-10.52442741394043,-12.662067413330078,-10.656278610229492,-11.697797775268555,-9.888535499572754 -4730,4730,R273A,0.018505737,0.004479534,0.029985123,0.024175599,-0.007123175,-0.009816535999999999,0.012780626000000002,0.024230847000000003,0.02162181,-0.017019972,0.025979039,-0.022359471000000002,0.082329716,0.013357025,0.034994172999999996,-0.049828471,0.035582121,1.477318857,2.287625184,-0.324098868,0.133507607,-1.223462738,-0.319495857,0.11903949,-0.33008284,-0.35388106700000005,1.096669928,-2.860316753387451,-4.011157989501953,-1.91493558883667,-2.817291021347046,-3.1959245204925537 -4731,4731,R273C,-0.026973725,0.027862282999999998,0.007180046999999999,0.016976524,-0.193968327,-0.010930371000000001,-0.055475495,0.0015280460000000001,-0.020744321,0.056686897,-0.0009623310000000001,-0.014319152,0.028679245,0.016310856999999998,0.01764219,-0.15095692800000002,-0.236979726,1.425311276,2.2410107999999997,-7.167574728,-7.076200127000001,-7.268829887000001,-7.843083702,-7.002174461,-6.647585464,-6.742537716,-5.801072034,-9.107955932617188,-8.766267776489258,-9.694493293762207,-9.82049560546875,-10.852485656738281 -4732,4732,R273E,0.042509079000000005,0.04073606,-0.001431225,0.059097727,-0.0075426830000000005,-0.086908501,0.057661653,0.027356505,-0.027247856,0.088035565,-0.006563445,-0.028627429,0.025764979,0.090895074,0.02730038,0.025483111,-0.040568476,1.26322028,2.092326537,-1.247453065,-1.895240761,-1.791038689,-0.8741535109999999,-0.46116127799999995,-1.215671089,-1.4617967180000002,0.13816734,-4.539876937866211,-6.306215286254883,-4.040485382080078,-4.944934368133545,-5.428759574890137 -4733,4733,R273D,0.062110096,-0.04360097,0.038240759,0.09257050900000001,-0.13876223199999999,-0.004715745,0.08336307700000001,0.040857115,-0.02243195,-0.062786352,-0.024415588,-0.013229329,0.089710847,0.037521763,0.147619255,-0.165095325,-0.112429139,1.18809423,2.79001725,-3.3930288589999997,-4.000329651,-3.473650543,-3.2418055110000004,-2.8181932069999998,-3.431165382,-2.414712372,-0.524166577,-5.779852390289307,-7.222143173217773,-5.124375343322754,-5.754735469818115,-6.497375965118408 -4734,4734,R273G,0.018874513,0.00628894,-0.011514123000000001,-0.002030531,-0.083012415,-0.04991393,0.01869116,0.019057866,-0.0005230359999999999,-0.00063772,0.013215600000000001,-0.037623271,0.014595026,0.015567673,-0.019628735,-0.096377486,-0.069647343,1.485328664,2.4096806269999997,-3.013665625,-2.946638252,-3.409270218,-3.0519548110000003,-2.805581291,-2.854883553,-2.7157689830000002,-1.490549708,-5.717788219451904,-5.534002780914307,-5.115665435791016,-5.222366809844971,-6.134220600128174 -4735,4735,R273F,0.06396334099999999,0.014845793000000001,0.00685101,0.018896259,-0.126650445,-0.128652891,0.074732887,0.053193794,0.05721176099999999,0.015036241,0.014655345,-0.014319152,0.028021171,-0.012578708999999999,0.050371227000000005,-0.153208431,-0.10009245900000001,1.4412421309999999,2.390395704,-7.603258415,-7.076874312999999,-8.154137032000001,-9.055799377,-7.987339874,-5.742141479,-5.469725324,-4.472452335,-8.306262969970703,-8.915909767150879,-8.85496997833252,-8.66090202331543,-9.982691764831543 -4736,4736,R273I,0.111033003,0.033559082000000004,0.053260870999999994,0.105435155,-0.016893345,-0.083017406,0.095037074,0.12702893099999998,-0.03444175,-0.030721249,0.09783941199999999,-0.071357653,0.177879395,0.071742177,0.139128132,-0.10609863800000001,0.072311949,1.220591271,2.379905549,-5.222427307,-5.197386101,-5.9456239779999995,-5.745323364,-3.87235141,-5.3514516830000005,-4.220002071000001,-2.664720253,-6.260484218597412,-6.972705841064453,-6.385598182678223,-6.529374599456787,-7.132275581359863 -4737,4737,R273H,0.034104136,-0.04540119,-0.023436111000000003,-0.031029955,-0.019283043,-0.068105809,0.042492322,0.025715949,0.015712854,-0.072489785,-0.018312593999999998,-0.091393001,0.04452078,-0.08416277300000001,0.022102864,-0.083069237,0.044503151,1.274568405,2.2671895280000003,-3.642267139,-4.396216843,-3.6486232760000004,-3.979755135,-3.408601692,-2.778138748,-4.111279923000001,-2.232376773,-5.559025764465332,-6.004887580871582,-5.773553848266602,-5.706178188323975,-6.086098670959473 -4738,4738,R273K,-0.018940675,0.021323883,0.0030958340000000004,0.051887744000000006,-0.048172532000000004,-0.018099133,-0.019516814,-0.018364535,-0.060835754000000006,0.08374131,-0.041093545,-0.034810627999999996,0.041002296,0.047902039,0.055873448,-0.059058633,-0.037286431,1.280462821,2.298336825,0.13892231900000002,0.42226040600000003,0.19859412399999998,-0.627759903,0.448933121,0.252583847,-0.0760093,0.00500682,-3.7431676387786865,-3.9107353687286377,-2.9275870323181152,-3.5416035652160645,-3.344104290008545 -4739,4739,R273M,0.000195402,-0.034678861,-0.018451323999999998,-0.007985131999999999,-0.104095374,0.015127633,0.017280653,-0.01688985,-0.11113136800000001,-0.025329743,-0.044027977999999995,-0.0045461370000000004,-0.032356511,-0.0015833239999999999,-0.014386939,-0.103163636,-0.10502711199999999,1.339676866,2.420110777,-4.794306494,-5.157402779,-5.705244652,-5.129123802,-3.702047157,-4.277714081,-4.870563985,-3.23376571,-6.921062469482422,-7.364828586578369,-6.571254730224609,-6.809510231018066,-7.674823760986328 -4740,4740,R273L,0.04899171099999999,0.031334926,0.01400842,0.025461197,-0.034706069,-0.053244398,0.052857642999999996,0.045125779000000005,-0.011952846999999999,0.025880822,0.03678903,-0.049202181,0.07721902,-0.006813653,0.057736046,-0.080318666,0.010906528,1.220664437,2.171555293,-3.5382469480000003,-4.324511459,-4.415751724,-3.3844700089999997,-2.182647354,-3.383854195,-2.76941412,-1.4160594219999998,-5.3194355964660645,-5.856965065002441,-5.133793830871582,-5.410602569580078,-6.2883806228637695 -4741,4741,R273N,0.035933452000000005,-0.0010236380000000001,-0.061501362000000004,0.003042483,-0.062109925,-0.022501899,0.061850529,0.010016375,-0.023322237000000003,-0.028218373999999997,0.026171099,-0.096436891,-0.026565832,0.00038626800000000005,0.005698697,-0.079105995,-0.045113855,3.342225137,1.9434087919999998,-3.8821213410000004,-4.422082245,-2.714630783,-4.93126548,-4.3194236980000005,-3.023204498,-3.904892764,-1.8090126430000002,-5.747463226318359,-6.290896892547607,-5.228889465332031,-5.370177268981934,-6.0306715965271 -4742,4742,R273Q,0.067728353,0.018543393000000002,0.016264485,0.028926992999999998,0.0042988309999999995,-0.110088715,0.045506381,0.089950325,0.030393712000000003,0.015333195,0.02175359,0.011506787,0.021022183,0.044148915999999996,0.01370507,0.016085246,-0.007487585,2.9223725469999997,1.92541614,-0.342386234,-0.966286034,-1.031754082,-0.14914159400000002,0.530850739,-0.095600197,-1.7954531459999998,-0.432433112,-3.6637682914733887,-4.388687610626221,-3.191148281097412,-3.6676385402679443,-3.7809765338897705 -4743,4743,R273P,-0.026607738,-0.068729342,-1.2892827340000002,-1.9997875019999998,-2.463472371,-0.06599882,-0.016948346,-0.03626713,-0.005614903,0.006094077,-0.14355276,-1.0273674940000002,-1.551197973,-1.930384197,-2.069190807,-2.2211054409999997,-2.705839301,1.149456302,2.659380698,-3.67158058,-4.099583748,-4.729502495,-3.982655914,-4.298177094,-1.24798365,-3.1647398389999997,-0.987750462,-7.408925533294678,-8.324445724487305,-6.451206207275391,-7.3098297119140625,-8.550817489624023 -4744,4744,R273S,0.035589459,0.014387298,0.033143757999999995,0.030517715,-0.030727435,-0.033809835,0.041534517,0.029644401,0.018593112,0.03647879,-0.007704195,0.002953752,0.063333763,0.027577486000000002,0.033457943999999996,-0.039289698,-0.022165171,1.286724075,2.519362906,-2.617100127,-2.480164375,-2.89774894,-3.0819883189999997,-2.900401825,-1.725197174,-2.8814062469999997,-1.251553269,-5.219751358032227,-5.718413352966309,-4.517724990844727,-4.892534255981445,-5.384896278381348 -4745,4745,R273T,0.048148572,0.006090244,0.035820394,0.038846351,-0.017076403,-0.060537325,0.055513577,0.040783567,0.070950859,-0.0035442290000000003,0.015724716,-0.025905407999999998,0.097546196,0.02552207,0.052170630999999995,-0.03004566,-0.004107145,1.243379167,2.524836693,-2.322740489,-1.462617592,-3.38855645,-3.132381645,-2.608725479,-1.02142128,-2.270420623,-1.221977713,-5.093729019165039,-5.635367393493652,-4.305839538574219,-4.527381896972656,-5.267935752868652 -4746,4746,R273W,-0.010066024,-0.017464948,-0.021480287999999997,-0.04342646,-0.143334305,-0.06201426,-0.015919642,-0.004212405,-0.009055515,-0.028625654,-0.006304242,-0.096827251,0.053866675,-0.052361616,-0.034491304,-0.183777352,-0.10289125699999999,1.58062497,2.248609267,-7.0535316539999995,-7.135460411,-7.032980736,-7.772044701,-7.275353966,-6.051818459,-5.658644195,-4.516170188,-9.13839054107666,-9.797929763793945,-9.80208969116211,-9.633548736572266,-10.330521583557129 -4747,4747,R273V,0.027985072000000003,-0.01703843,-0.020673321,0.01846637,-0.039767452,-0.047406937,0.037279353,0.018690791000000002,0.047119062,-0.041464767,0.007387908,-0.057855183,0.016508542,-0.000282391,0.03721513,-0.08940306699999999,0.009868164,1.4643506869999998,2.4719636019999998,-4.202275642,-3.872183746,-5.012561462,-4.823983635,-3.63109774,-3.671551628,-4.071774254,-1.526447816,-5.298345565795898,-6.338898181915283,-5.209630966186523,-5.50631046295166,-6.058140754699707 -4748,4748,R273Y,0.037664913,0.025705977,-0.006541016,0.030847416000000003,-0.042931939,-0.008036299,0.06853355,0.0067962759999999995,-0.011712648999999999,0.003082427,0.048329526,-0.08158728400000001,0.068505253,-0.04050139,0.10219622199999999,-0.12376644699999999,0.037902569,1.4301309869999999,2.273058002,-7.246611481,-7.059349777,-7.984315125,-8.628974342000001,-7.557939987,-5.002478172,-5.311325,-4.2474545610000005,-8.35554313659668,-8.583683013916016,-8.814894676208496,-8.736749649047852,-9.733440399169922 -4749,4749,Q274A,-0.02754578,0.029658929,-0.021099838,-0.013000835,0.021095374,-0.015979021,-0.057881992,0.0027904329999999997,-0.008547971,0.042513639000000006,0.016804219,-0.023122076000000002,-0.019077599,0.034365293,-0.060366962,0.008090606,0.034100141,1.190771732,2.752532561,-1.102549677,-0.692565842,-1.990490845,-1.059884201,-0.953784889,-0.816022606,-2.101624955,3.5954671119999997,0.25301218032836914,1.819919466972351,2.2325351238250732,2.837144613265991,1.358627438545227 -4750,4750,Q274C,-0.034845223,-0.0028397970000000002,-0.018970993999999998,-0.049068637000000005,0.0025160210000000002,-0.06502609599999999,-0.033543516,-0.03614693,0.06762066900000001,-0.013867186,0.008187593,-0.029943453,-0.007998534,-0.005666043000000001,-0.092471231,-0.046388114,0.051420155999999995,1.24347922,2.4438950569999998,-5.934735515,-6.250626595,-7.493432808,-5.16841536,-5.218411995,-5.542790817,-4.720510291,-0.7034468220000001,-3.409219980239868,-2.9138007164001465,-4.349535942077637,-3.863645076751709,-3.891636371612549 -4751,4751,Q274E,-0.08979142300000001,-0.002434464,-0.031554087,-0.025829117999999998,-0.05505396,-0.020936808,-0.081885061,-0.097697785,-0.025490468999999998,0.019321256999999998,-0.024190184,-0.003050122,-0.060058052,0.045272407,-0.096930642,-0.002373705,-0.10773421400000001,1.228452329,2.731102576,-3.4557889189999997,-2.9013688510000004,-4.3528713230000005,-3.208870003,-3.2530708010000002,-3.562763618,-4.616312925,-0.82296096,-4.341062545776367,-4.127255916595459,-4.469671726226807,-4.716330528259277,-4.719321250915527 -4752,4752,Q274D,-0.057334305999999995,-0.014953251,-0.025441746,-0.932921418,-1.9017767319999999,-0.027662326,-0.024317016,-0.09035159599999999,0.028291042000000002,0.000484625,-0.030391127,-0.005872212,-0.04501128,-0.291156263,-1.5746865730000001,-1.897705275,-1.905848189,1.343076584,1.346752705,-6.304823141,-6.880741699,-6.949713211000001,-5.481692154,-6.33057518,-5.881393462999999,-5.665175141000001,-1.331591637,-5.149959564208984,-4.452584266662598,-6.023637294769287,-6.499692440032959,-6.215644836425781 -4753,4753,Q274G,-0.07327827099999999,0.008315531,-0.038020694,-0.026330595,-0.353408171,-0.0030403759999999996,-0.047722342,-0.0988342,0.034946225,0.002483058,0.014148003000000001,-0.03166225,-0.044379137,0.008119975,-0.060781165,-0.256378787,-0.45043755399999996,1.201104751,1.865490809,-5.492237659,-5.051880699,-5.329519737,-6.606426476,-4.6330928039999995,-5.840268578,-4.229653161,-0.8107271909999999,-4.096196174621582,-2.0607199668884277,-2.215585708618164,-0.7826712131500244,-3.202530860900879 -4754,4754,Q274F,-0.10023003300000001,-0.081638334,-0.056645376,-0.117635813,-0.114884101,-0.0022561670000000003,-0.082589833,-0.117870233,0.016611891,-0.083907022,-0.079369645,-0.040424062999999996,-0.072866689,-0.081685562,-0.153586063,-0.156704972,-0.07306323,1.5867351440000002,2.344134907,-5.33403903,-7.459368454,-5.960101906,-3.904954262,-4.704722191,-4.64104834,-4.310036051,1.7293664930000001,-1.91817307472229,-2.995553493499756,-4.141921520233154,-4.4071173667907715,-2.9995312690734863 -4755,4755,Q274I,-0.056472466,-0.028563112999999998,-0.046709266,-0.041060762,-0.035070981,-0.041459156000000004,-0.07410828400000001,-0.038836648,-0.037166679,-0.01021364,-0.046912585,-0.005384877,-0.088033654,0.064419978,-0.146541501,-0.040970252,-0.029171709,1.2473635490000001,2.50703257,-4.874457727,-5.506892487000001,-5.723455872000001,-4.735490073999999,-3.6218655010000003,-4.784584702,-3.223416532,2.962734471,0.06558871269226074,0.6493825912475586,-0.7180900573730469,-2.257866382598877,1.2615424394607544 -4756,4756,Q274H,-0.030290297,-0.019757025,-0.026608395,-0.042476731,0.015989086,-0.054399293,-0.045579048,-0.015001546000000001,0.044899594,-0.007341955,-0.032172095,-0.009450763000000001,-0.043766026,0.009391987,-0.09434544800000001,-0.011627443000000001,0.043605615,1.3226672940000002,2.617897504,-1.999197383,-1.937262024,-2.233154129,-1.6519496,-2.210432175,-1.9631889880000002,-2.8312708860000004,-0.97008381,-3.809706926345825,-3.1819887161254883,-4.696915149688721,-5.168069362640381,-3.499630928039551 -4757,4757,Q274K,-0.097588815,-0.005958817,-0.049797234,-0.07042327,-0.067261017,0.011097933999999999,-0.081277432,-0.113900197,0.045364798,-0.052152205,0.040234571000000004,-0.011845231000000001,-0.087749237,-0.014451801,-0.126394739,-0.039445789,-0.095076245,1.371620235,2.5098517890000003,-3.473255493,-3.9970622710000003,-3.0793628460000004,-3.6209071880000003,-3.590927505,-3.078017654,-3.671408533,0.023799141,-3.9396755695343018,-1.7913928031921387,-3.3679332733154297,-3.351032257080078,-2.4919638633728027 -4758,4758,Q274M,0.00298749,-0.001099673,-0.024342928,-0.030054905,-0.0016282929999999998,-0.036004707000000004,0.010584988,-0.004610008,0.089567635,0.015477611,-0.017676956,-0.011774894,-0.036910961,0.008115453,-0.068225263,-0.027887067,0.024630481,1.197209823,2.556279004,-5.265051324,-7.036064339,-4.402873131000001,-6.130845527999999,-3.379127281,-5.376346344,-4.261379713,1.4446319230000002,-1.221437931060791,-1.6345396041870117,-2.325958251953125,-3.1723294258117676,-1.5867118835449219 -4759,4759,Q274L,-0.046053971,0.004714327,-0.037633357,-0.036858275,0.004304036,-0.011092435,-0.053040132999999996,-0.039067809,0.038772548999999996,0.021537887999999998,-0.012109233999999998,-0.016169186000000002,-0.059097527999999996,0.020245785,-0.093962335,-0.005488021,0.014096092,1.190206942,2.541524194,-3.843356313,-4.811871841,-4.614285011000001,-4.275255737,-2.509185249,-3.006183723,-2.1226470109999998,3.930502995,0.7937178611755371,-0.6894803047180176,-0.8600280284881592,-2.048126697540283,-0.3025040626525879 -4760,4760,Q274N,-0.02165357,0.036975346,0.012456123000000001,0.0013372870000000002,-0.138912435,-0.071280642,-0.003242977,-0.040064163,0.021133337000000002,0.010094737,0.063855954,0.013094888999999998,0.011817356999999999,0.030782933,-0.028108359,-0.15591688,-0.12190798900000001,1.365674417,2.205348155,-5.397968929,-6.603283012,-5.025456116,-5.368490746,-5.779229667999999,-4.213385101,-6.077844621000001,-0.9418265659999999,-4.902880668640137,-3.24459171295166,-4.875088214874268,-5.0516228675842285,-4.208003997802734 -4761,4761,Q274P,-0.024265742000000003,-0.017481211,-0.04224768,-0.609354677,-1.761989201,-0.049787232,-0.042886424000000006,-0.005645059,0.027540737000000003,-0.013510811000000001,-0.02145161,-0.032725221,-0.051770138,-0.13854423300000002,-1.08016512,-1.783378427,-1.740599974,1.0374318340000002,1.327565316,-6.4231833389999995,-6.503982506,-8.183305969,-6.722671806,-5.413595261,-5.292361153,-4.452036092,-0.189699885,-5.69718074798584,-6.001620769500732,-5.1818623542785645,-4.746127605438232,-5.152926445007324 -4762,4762,Q274S,-0.018790166,-0.001162914,-0.035876873999999996,-0.029355452999999997,-0.036141202000000004,-0.021899362000000002,-0.005679948000000001,-0.031900383,0.005164422,0.0072364809999999995,-0.009562308,-0.019284496,-0.052469252,0.017098546000000003,-0.075809452,-0.045265220999999994,-0.027017182999999997,1.312288508,2.527666673,-5.320170287,-5.967720619,-5.264715027,-5.101610611,-5.610961014,-4.655844162,-4.943891226,0.208434426,-3.200889825820923,-1.7670636177062988,-1.6929545402526855,-1.5818791389465332,-2.1266422271728516 -4763,4763,Q274R,-0.032040683,0.0035277579999999998,-0.01055972,-0.034706796,-0.067524796,-0.038870853,-0.027184497000000002,-0.036896868,0.05452811900000001,-0.008997674,0.01605319,-0.011620107,-0.009499332,-0.008973753000000001,-0.060439837999999996,-0.08738589199999999,-0.047663699000000004,1.32176643,2.289655704,-3.29577074,-3.9028213810000003,-4.443630898,-3.174662544,-2.990900902,-1.966837975,-4.849690658,0.8186029340000001,-3.748943567276001,-2.539889335632324,-3.7705769538879395,-3.586745262145996,-2.62945556640625 -4764,4764,Q274T,-0.0071633090000000005,0.00249145,-0.041306344,-0.044343234,-0.039528661,-0.015292961,-0.0076025419999999995,-0.006724075,0.033595276,-0.020531483,0.025514382000000002,-0.030299127999999998,-0.052313559,-0.042113233,-0.046573235,-0.076353325,-0.0027039959999999997,1.3220483570000001,2.325197464,-4.028962235,-4.355695297,-3.95744902,-3.95602137,-3.456609756,-4.419035728,-2.975386199,2.408775785,-1.2628569602966309,0.013552188873291016,-0.10297465324401855,-1.406217098236084,-0.38177490234375 -4765,4765,Q274W,-0.036701978999999996,0.010252566999999999,-0.028438751,-0.034740095,0.022395673999999997,-0.017440202,-0.038611406,-0.034792552000000004,0.027190982000000002,-0.002678588,0.023183722,-0.040088765,-0.016788736999999998,-0.031673900000000005,-0.03780629,-0.009562859,0.054354207,1.338230023,2.622232115,-6.145883347000001,-5.344316948,-9.670859161000001,-5.126168312,-5.833386947999999,-4.754685364,-4.220553165,-0.38467381100000003,-4.94964599609375,-5.1090922355651855,-6.991508960723877,-7.179222583770752,-5.981544494628906 -4766,4766,Q274V,-0.012650797,0.002679929,-0.060767977,-0.03978115,0.017103224,0.00667329,-0.020314443999999997,-0.004987149000000001,0.032997487,-0.010302667,0.015662525,-0.067999763,-0.053536191,-0.006491584,-0.073070715,-0.022713142000000002,0.05691959,1.424047875,2.571789416,-3.0260135989999997,-3.444137436,-3.467461472,-3.188999763,-2.6041841740000002,-2.425285149,-2.58519043,3.5400173280000002,0.7316489219665527,2.3622560501098633,1.847029447555542,-0.03837227821350098,2.186398506164551 -4767,4767,Q274Y,0.031832519,-0.05278257,-0.009744519,-0.011870995,-0.092507326,-0.060205065999999995,0.045408826,0.018256212,-0.014248756999999999,-0.12553566800000002,0.019970528,-0.09215713199999999,0.072668095,-0.029822186,0.0060801959999999995,-0.131773026,-0.053241625,1.396540044,2.246416119,-3.919916275,-3.779225685,-4.308113823,-3.395153397,-4.385569664,-3.7315188060000004,-4.778929562,0.36715087,-3.9585764408111572,-3.089402198791504,-5.776504039764404,-5.498946666717529,-3.9908432960510254 -4768,4768,I275A,-5.5700000000000005e-05,-0.001879209,-0.907259057,-1.897835977,-2.439738277,-0.018365913,-0.000172589,6.11e-05,0.037939416000000004,-0.005602735,0.001844318,-0.46669551600000003,-1.347822597,-1.7562533359999999,-2.039418618,-2.210942674,-2.66853388,2.926105798,1.749676944,-8.628404227,-5.871428986000001,-9.074587952,-13.91504097,-6.8009349210000005,-7.480028305,-6.08182364,-4.321669498,-6.360713005065918,-11.469342231750488,-6.972076416015625,-9.866828918457031,-8.693672180175781 -4769,4769,I275C,0.001317929,0.010862874,0.06506297400000001,-0.81046375,-1.8161600709999999,-0.026790507999999998,0.007562131999999999,-0.0049262740000000005,0.065763425,0.023151353,-0.001425606,0.051474385,0.07865156200000001,-0.164941184,-1.455986316,-1.959578584,-1.672741558,1.046489202,1.3131823870000001,-11.61364077,-8.487767586,-13.36587415,-16.1395902,-9.143384575,-10.93158732,-7.360391935,-4.994998004,-8.148261070251465,-12.624029159545898,-9.971899032592773,-12.432738304138184,-8.791722297668457 -4770,4770,I275E,-0.024310809,-0.8179078609999999,-1.858319974,-2.162027079,-2.747169622,-0.006516704,0.028864921,-0.07748653900000001,0.102833455,-0.5269196979999999,-1.108896023,-1.843609066,-1.873030881,-1.886422176,-2.437631982,-2.517202773,-2.97713647,3.436198511,1.6061418280000002,-12.68330055,-10.15234972,-12.66823276,-19.09430688,-10.05683628,-11.44477711,-8.028282977,-6.187012801,-10.959986686706543,-15.84830093383789,-11.55165958404541,-13.088751792907715,-12.863807678222656 -4771,4771,I275D,-0.027642266000000002,-1.3493099119999998,-2.02553685,-1.876731713,-2.93899551,0.020008385,0.01238098,-0.067665512,0.059753875,-1.345933569,-1.352686255,-2.4432629869999998,-1.6078107130000001,-1.963197352,-1.7902660730000002,-2.718916686,-3.1590743339999996,0.036634672,-0.827690447,-14.49114027,-11.14731986,-15.0238857,-21.51391459,-11.50844238,-13.26213882,-8.649820737999999,-7.07168951,-10.363921165466309,-16.371501922607422,-12.411443710327148,-14.49303150177002,-13.732173919677734 -4772,4772,I275G,0.007728294,-0.690030128,-1.9168383219999998,-2.021057465,-2.711967313,-0.016715279,0.018808524,-0.003351936,0.064603335,-0.39183775600000004,-0.988222499,-1.9818219369999999,-1.851854706,-1.991842534,-2.050272395,-2.642826517,-2.781108108,1.172262815,-0.116360483,-12.18518138,-9.228764404,-13.14955711,-18.47198851,-9.461589577,-10.61400731,-7.234858163999999,-4.6340088680000004,-9.873160362243652,-13.784860610961914,-8.871587753295898,-13.91148567199707,-11.86894416809082 -4773,4773,I275F,-0.022057005,0.046488095,0.071046295,0.133818796,0.08968222,-0.09637305199999999,-0.037085979,-0.007028031,0.042079969,0.119099186,-0.026122997000000002,0.19316590600000003,-0.051073317,0.192317297,0.07532029400000001,0.16537878,0.01398566,1.031816043,3.1957912910000004,-6.495315529,-3.968827751,-6.058925987,-7.151225693,-8.100083076,-7.197515137000001,-4.969172221,-2.749201696,-6.0837297439575195,-8.185891151428223,-8.2816162109375,-7.460484504699707,-3.8838367462158203 -4774,4774,I275H,-0.010020651,-0.119131267,-1.553084219,-2.044714542,-2.541811455,-0.018157193000000002,0.023593887,-0.043635189000000005,0.063663851,0.005844477,-0.24410701,-1.242420715,-1.8637477219999998,-1.9286865009999998,-2.160742583,-2.2584371030000003,-2.825185807,2.972801913,1.507527499,-10.242102599999999,-4.681064903,-10.04069859,-18.11421626,-8.109189835,-10.26534341,-4.9856331780000005,-3.099209262,-5.600955963134766,-11.226716041564941,-10.54350471496582,-7.538946151733398,-7.021411418914795 -4775,4775,I275K,-0.091123242,-1.393714747,-2.463404273,-2.3207163630000003,-2.755343908,-0.05504843400000001,-0.09327105599999999,-0.088975427,0.063614058,-1.299840845,-1.487588649,-1.950012232,-2.976796313,-1.8959153290000001,-2.745517397,-2.526695927,-2.983991889,4.002667298,1.808555359,-14.08305897,-11.37246316,-14.46673823,-20.33527316,-10.65150823,-13.58931207,-8.877430577,-7.530862831,-12.47910213470459,-15.551148414611816,-12.906343460083008,-12.417469024658203,-12.962699890136719 -4776,4776,I275M,0.005011609,0.01145538,0.008364801,0.068967406,-0.220181281,-0.060829522999999996,-0.020612242,0.030635459,0.03674778,0.02014419,0.0027665690000000004,0.0398076,-0.023077999,0.083741608,0.054193204,-0.14644568800000002,-0.293916874,1.396122805,2.24667422,-5.816622015,-4.9127257460000004,-6.344098686000001,-7.705639113999999,-5.591704826,-4.528941704,-5.161657537,-1.90397913,-5.624643802642822,-7.44478178024292,-7.123270511627197,-5.627677917480469,-5.770766735076904 -4777,4777,I275L,0.056018095,0.049227169,0.089926485,0.112805758,-0.126616109,-0.05108165,0.057994493,0.05404169599999999,0.074081672,0.030150813,0.068303525,0.125666109,0.05418686,0.117795974,0.107815541,-0.077256054,-0.175976164,1.271819585,2.468221541,-4.506190892,-3.042512505,-5.864920906,-5.910533096,-4.204286324,-3.50870163,-4.292800442,-1.17338686,-5.240544319152832,-6.1291608810424805,-5.582425594329834,-4.010782241821289,-4.14262056350708 -4778,4778,I275N,-0.071911453,-0.935497664,-2.0167078419999998,-1.8914009859999998,-2.476543529,0.030376371,-0.00039591699999999997,-0.143426988,0.10927174199999999,-0.578055203,-1.292940125,-2.201354444,-1.83206124,-1.721288809,-2.0615131630000003,-1.999886888,-2.9532001689999996,1.4268040569999998,-0.070778581,-13.18685235,-9.91385199,-15.78229115,-19.18212263,-10.20297526,-10.85302074,-7.7085683629999995,-5.5627872929999995,-6.676876544952393,-12.963445663452148,-8.097042083740234,-9.62760066986084,-9.292081832885742 -4779,4779,I275Q,0.013188595,-0.723883319,-2.151574516,-2.412943844,-2.642484156,0.02191641,0.076791279,-0.050414089,0.09288252400000001,-0.328658888,-1.119107749,-2.393803623,-1.9093454090000002,-1.6706999390000001,-3.155187748,-2.192336067,-3.092632244,0.160303953,-0.47284944100000004,-12.23651223,-8.633685295,-12.57918719,-20.67984286,-8.843507675,-10.44633812,-6.903414712000001,-5.287203797,-8.809706687927246,-14.424452781677246,-9.934569358825684,-8.450663566589355,-8.178135871887207 -4780,4780,I275P,0.022229712999999998,-1.405739811,-1.9221664459999999,-2.097080973,-3.0192967260000003,-0.010203057,0.041431813,0.0030276120000000003,0.08977777099999999,-1.311993782,-1.499485839,-1.944436403,-1.899896489,-1.93289185,-2.261270096,-2.77293207,-3.265661382,-0.031497897000000004,-0.792920582,-13.22762707,-11.0939675,-13.88031013,-17.90375451,-11.07412482,-12.18597839,-9.172198157999999,-8.156429405,-12.907854080200195,-15.333863258361816,-11.243900299072266,-13.183351516723633,-13.171690940856934 -4781,4781,I275S,0.031733741,-0.568478224,-1.846610425,-2.225655363,-2.732310421,-0.017603403,0.046700369000000005,0.016767113,0.060075475,-0.296687048,-0.8402693990000001,-1.912359458,-1.7808613919999998,-2.034353814,-2.4169569109999998,-2.5304358380000003,-2.9341850039999997,1.090730298,-0.061691949,-11.79798542,-8.561685974,-13.64867404,-16.68234362,-9.443138817000001,-10.65408466,-7.81536612,-6.119520047000001,-7.525030612945557,-13.399234771728516,-8.942756652832031,-11.640624046325684,-9.939810752868652 -4782,4782,I275R,0.016134171,-1.3516428809999999,-1.860747491,-2.17145896,-2.93873551,-0.0035862529999999998,0.025825478,0.006442864,0.044545941,-1.337358452,-1.36592731,-1.897353209,-1.824141772,-2.182074862,-2.160843058,-2.53202885,-3.3454421689999996,0.176498264,-0.797088182,-15.21142708,-10.38273331,-15.54736574,-24.54202978,-11.6608839,-13.924122699999998,-9.663760142000001,-9.382515756,-9.808445930480957,-14.875551223754883,-12.941590309143066,-11.691783905029297,-11.818428993225098 -4783,4783,I275T,0.0013983079999999998,0.019620932,-0.01224561,-1.429135768,-2.361641829,0.005331054,0.020080305,-0.01728369,0.047477585,0.017967398,0.021274466000000002,0.059026498,-0.083517718,-1.129714466,-1.728557069,-2.172675511,-2.5506081469999997,2.16250571,1.437562065,-10.39823908,-7.162806357999999,-11.00073662,-15.66569762,-8.241904968,-9.920049828,-7.2065983760000005,-4.165364197,-6.6086506843566895,-11.134737968444824,-6.453179836273193,-9.113475799560547,-7.8786773681640625 -4784,4784,I275W,0.001324006,0.06530680900000001,-0.727406672,-2.138034597,-2.362077217,-0.024013261,-0.001442086,0.004090097,0.066214352,0.096664648,0.03394897,-0.282119518,-1.172693826,-1.661238384,-2.61483081,-2.229871074,-2.49428336,1.0564675609999998,0.719535757,-13.23391374,-10.38550916,-13.62061644,-16.68403116,-12.36211575,-13.11729621,-9.206607206000001,-8.422806375,-9.59781551361084,-14.060161590576172,-12.272066116333008,-13.438349723815918,-11.08029556274414 -4785,4785,I275V,0.049367068,0.025095562000000002,0.074328659,0.057454615,-0.044125186,-0.011119292,0.041209567999999995,0.057524567,0.057081464000000005,-0.003575052,0.053766175,0.070909654,0.07774766400000001,0.026311362,0.08859786800000001,-0.028520841,-0.059729530999999995,1.22798405,2.501998941,-3.5878606960000003,-3.277573555,-4.585765793,-3.631633484,-3.7211632389999996,-2.723167412,-3.268839807,-1.669670789,-4.548623561859131,-6.114587783813477,-4.006936073303223,-5.9039411544799805,-4.511800289154053 -4786,4786,I275Y,-0.011969448,0.005181589,0.015867115,-0.10169401,-1.6145716559999999,-0.10473864,-0.0041458929999999995,-0.019793002,0.082529717,0.00209299,0.008270188000000001,0.002341216,0.029393014,0.134580382,-0.33796840200000006,-1.501432742,-1.72771057,0.613126077,1.314897246,-10.33422766,-5.585998665,-10.01471344,-13.87063116,-10.76400658,-11.43578845,-6.8057693079999995,-5.794613976,-5.982609272003174,-12.971022605895996,-11.028857231140137,-9.55528450012207,-7.135676383972168 -4787,4787,A276C,-0.003691325,-0.007567267,-0.034851925,-0.013809043,-0.299150607,-0.01239783,0.006958269,-0.014340918999999999,-0.002813853,0.0029453540000000003,-0.018079888,-0.059616487,-0.010087361999999999,-0.046716463,0.019098377,-0.20174115899999998,-0.396560055,1.3951510409999999,2.09388478,-8.902840063,-9.479266327000001,-7.659302391000001,-8.794620659,-9.264240295,-9.316770645,-7.4594607129999995,-6.985155437,-10.589115142822266,-11.374567031860352,-10.960471153259277,-10.63160228729248,-11.967674255371094 -4788,4788,A276E,0.025743792999999997,-0.018260546000000002,-0.008491644,-0.056446055999999994,-0.779277688,-0.094396934,0.012542413999999998,0.038945171,0.059615667000000004,0.001391735,-0.037912826000000004,-0.059745165999999995,0.042761879,-0.08365637599999999,-0.029235736000000002,-0.666112974,-0.892442402,1.22661298,1.577312765,-5.658824867000001,-5.103459999,-5.0052481,-5.711222237,-5.203573029,-7.270620972000001,-4.807635564,-3.873384123,-8.405061721801758,-11.563271522521973,-7.89164400100708,-8.008527755737305,-9.923526763916016 -4789,4789,A276D,0.020969803999999998,-0.022287445,-0.026263375,-0.107828254,-1.550481094,-0.081249362,0.015420287,0.026519321000000002,0.062400544,-0.014465132,-0.030109757999999997,-0.067107908,0.014581159,-0.053294243,-0.162362264,-1.76720407,-1.3337581170000001,0.6965749940000001,1.307969311,-8.536827275,-7.963535721,-6.846053658,-9.227985634,-8.780190597999999,-9.866370766000001,-7.505735726,-7.043619969,-10.18582820892334,-12.8746337890625,-9.455655097961426,-10.917486190795898,-11.529248237609863 -4790,4790,A276G,0.015998185,-0.004739643,-0.0009911380000000001,-0.002452283,-0.344260545,-0.08267954799999999,-0.006600998,0.038597367,0.009483158,0.017718156000000002,-0.027197441,0.00971477,-0.011697046000000001,0.000716755,-0.00562132,-0.25409208,-0.434429009,1.344671111,1.996269239,-6.677811031,-8.839652237000001,-4.319663765,-6.9713041229999995,-6.513882324,-6.744552704,-4.738435478,-1.6205948890000001,-6.226869583129883,-6.700398921966553,-5.786685466766357,-6.794682502746582,-6.827710151672363 -4791,4791,A276F,-0.00579526,0.034680023,-0.010399528,0.010663297,-0.088089711,-0.038445528,-0.016242236,0.004651716,0.014163051000000001,0.067633149,0.0017268960000000001,-0.013003256999999999,-0.007795799,0.006005944,0.015320648999999999,-0.083169194,-0.09301022800000001,1.475690292,2.479203001,-10.39051915,-11.30129021,-8.536359917,-10.83515689,-10.43867031,-10.84111842,-8.262831524,-7.646493721000001,-11.011430740356445,-13.311636924743652,-10.435750961303711,-11.450089454650879,-12.172273635864258 -4792,4792,A276I,-0.029396546000000003,-0.047192387,-0.074074485,-0.018130476,-1.478838915,-0.024612554,-0.013915247,-0.04487784400000001,0.045984764000000004,-0.08684204699999999,-0.007542726,-0.067926817,-0.080222153,-0.021264741,-0.014996211,-1.368582815,-1.589095014,1.06508445,1.3707267630000002,-6.875732956,-6.111890869,-5.488025177000001,-6.890523537000001,-7.909661697000001,-7.978563499,-5.669073616,-5.408171702000001,-9.8545503616333,-11.462646484375,-9.46643352508545,-9.742321968078613,-10.44890022277832 -4793,4793,A276H,0.066314329,0.004690145,0.021401821,0.013457665,-0.0692059,-0.067168164,0.05521446,0.077414198,0.031627947000000003,0.027535382999999997,-0.018155094,0.032276724,0.010526917,0.016713293,0.010202036,-0.042233709,-0.09617809,1.237293081,2.4271013619999997,-8.157183571000001,-8.388799323999999,-5.4963376539999995,-8.723345573,-8.534674171,-9.642761131,-6.118951145,-5.34031814,-9.624115943908691,-11.421092987060547,-8.72394847869873,-9.676908493041992,-10.001932144165039 -4794,4794,A276K,0.038514898,0.052377365999999995,0.015396273,0.083233687,0.049749611,0.018550545,0.046471177999999995,0.030558617000000003,0.028856528,0.07043335,0.034321382000000004,0.055845725,-0.02505318,0.08930015300000001,0.07716722,-0.025887935,0.125387156,1.128780973,2.548236946,-5.238360808,-4.838803505,-4.47796521,-5.829384232000001,-6.313576744,-4.732074348,-4.7419756710000005,-3.927095871,-9.055634498596191,-10.45760440826416,-7.9939470291137695,-8.25971794128418,-8.382306098937988 -4795,4795,A276M,0.006500373,-0.011872373,-0.028492106,-0.002898514,-0.06703507,-0.031781883999999996,-0.012582429,0.025583174,0.000227273,-0.014443791000000001,-0.009300955,-0.072805092,0.015820881000000002,0.025625726,-0.031422754,-0.08250716,-0.05156298,1.453696401,2.540214447,-8.852096407000001,-8.859414886,-7.561922485,-9.116454453,-9.937026428,-8.78566378,-7.581251891,-6.985155314,-9.81893253326416,-12.482909202575684,-9.904104232788086,-9.728944778442383,-10.925617218017578 -4796,4796,A276L,-0.026929525,0.023245229,-0.002691207,0.015092895,-0.60293422,-0.040302901,-0.032863342000000004,-0.020995707000000002,0.018582493000000002,0.061921507,-0.015431048999999999,0.00567233,-0.011054743,0.01359942,0.016586369,-0.41986395200000004,-0.786004487,1.159694675,1.6881179240000002,-8.641094479,-8.296207008,-6.850186783,-8.505143593,-9.671116371,-9.882818642,-7.310066683,-6.501744154,-9.327828407287598,-12.235567092895508,-8.77172565460205,-9.669485092163086,-10.844348907470703 -4797,4797,A276N,0.043803224,0.039714012,-0.003578527,0.031504597999999995,-0.616039405,-0.057705016,0.044111267,0.043495180999999994,0.056400547999999995,0.028926075,0.050501948,-0.001669805,-0.0054872490000000005,0.02189597,0.041113226,-0.483240069,-0.74883874,0.9346151840000001,1.5331278419999999,-5.949938057000001,-6.403395676000001,-4.080609993,-7.073294197,-5.843129684,-6.349260735,-5.295184735,-3.892485484,-9.09577465057373,-10.880119323730469,-8.482820510864258,-9.696261405944824,-9.68721866607666 -4798,4798,A276Q,0.109645403,0.005176798,0.022556586,0.064583418,-0.052753796,-0.035765871,0.11078383800000001,0.10850696800000001,-0.039126135,-0.02549561,0.035849206,-0.074390716,0.11950388699999999,-0.008543919,0.137710754,-0.082898828,-0.022608762999999997,1.20113283,2.204479806,-5.2823442410000006,-5.346397568,-3.545718552,-5.531332977000001,-5.332157104,-6.656115005,-4.698797647,-2.5695604569999997,-7.07087516784668,-10.96521282196045,-7.24152946472168,-8.226573944091797,-9.017572402954102 -4799,4799,A276P,-0.029075922,-0.48701323,-1.8587887019999998,-1.984420003,-2.550635631,-0.023978329,-0.028431151,-0.029720693,0.003570411,-0.178639369,-0.79538709,-1.803928334,-1.913649069,-1.965548515,-2.003291491,-2.493029112,-2.60824215,0.9537680909999999,-0.027403395,-7.298451497,-7.703163116,-4.954476936,-7.557997589,-7.4981450039999995,-8.778474838,-6.735959052,-4.341025581,-11.97712516784668,-12.176039695739746,-10.963829040527344,-11.275599479675293,-11.879674911499023 -4800,4800,A276S,-0.012865521999999999,-0.013179221999999999,-0.039095185,0.004458084,-0.055652281,-0.025570238999999998,-0.032499169,0.006768125,0.050462402999999996,0.002448891,-0.028807334,-0.036569039,-0.041621331,0.004037329,0.004878839,-0.067147254,-0.044157308,1.227514043,2.331774979,-3.309900565,-4.604296677,-1.988797836,-3.3358695139999996,-3.3871080019999997,-3.2334307939999998,-3.514746058,-2.416510928,-6.727252006530762,-6.570413112640381,-6.282871246337891,-6.5975728034973145,-6.7742767333984375 -4801,4801,A276R,-0.016676092,-0.0054798469999999995,-0.005058986,0.01800028,-0.022418982,-0.030124675,-0.033011009,-0.000341174,0.00981527,0.021385806,-0.032345499,-0.005686259,-0.0044317129999999995,0.009135644,0.026864915,-0.021828139,-0.023009825,1.385781746,2.661995835,-5.21939511,-5.943340881,-3.397115608,-4.55450222,-6.327174706,-5.874842133,-4.026266985,-2.0664148890000003,-7.959808349609375,-9.026876449584961,-7.012651443481445,-7.744505882263184,-8.842765808105469 -4802,4802,A276T,-0.025133078,-0.011782298,-0.052611671,-0.027806374,-0.6621733879999999,-0.096130542,-0.035941982000000004,-0.014324173,0.011344963999999999,0.006797724000000001,-0.030362319,-0.044357333,-0.060866009000000006,-0.016772423999999998,-0.038840322999999996,-0.48588193799999996,-0.8384648370000001,0.971463038,1.5428088290000002,-5.0808588210000005,-5.643151787000001,-3.6542101060000003,-5.228705902,-4.96430304,-5.913923271,-5.225824281,-4.423774723,-7.678264617919922,-7.958717346191406,-7.391388893127441,-7.050372123718262,-7.739755630493164 -4803,4803,A276W,0.016703433,-0.018125741,-0.043425189,0.016847887,-0.9135135329999999,-0.124920766,-0.043672462,0.077079327,-0.006940261,-0.020962671999999998,-0.015288808999999999,-0.07517128,-0.011679098,-0.015837768999999998,0.049533542,-0.6806492259999999,-1.1463778390000001,0.904875215,1.4502244480000002,-11.20906292,-11.97157731,-9.099558417999999,-11.70535574,-11.44111526,-11.82770786,-9.062415357,-10.01779928,-12.907418251037598,-14.77595043182373,-12.634968757629395,-13.69611644744873,-13.675169944763184 -4804,4804,A276V,-0.022864566,-0.001704977,-0.021373407999999997,0.024532795,-0.172800332,-0.09194837,-0.042436969000000005,-0.003292163,0.020686917,0.043150965,-0.046560919000000006,0.007104803000000001,-0.049851618,0.032108585,0.016957005,-0.13186004699999998,-0.213740617,1.183900381,2.056735716,-4.337741606,-4.160464897,-3.174346199,-4.404865196,-4.663567055,-5.285464684,-4.012241135,-3.801842553,-7.943505764007568,-8.996743202209473,-7.975553035736084,-7.909462928771973,-8.386222839355469 -4805,4805,A276Y,0.022048751000000002,-0.007780253000000001,-0.016696146000000002,-0.004028275,-0.088587526,-0.064410324,-0.01885355,0.06295105200000001,-0.017966233999999998,0.003176037,-0.018736543,-0.034489147000000005,0.001096855,-0.055867707,0.047811157,-0.073288775,-0.103886276,1.494308414,2.495035222,-10.81876335,-11.2983976,-8.696537117,-11.23379858,-10.79633495,-12.06874851,-8.317371861,-7.646493721000001,-11.322280883789062,-12.576683044433594,-10.713430404663086,-12.106337547302246,-11.436907768249512 -4806,4806,E277A,0.020421894,0.010806663000000001,0.006846636999999999,-0.047800677,-0.084317277,-0.02851198,0.066287795,-0.025444007999999997,0.037917888999999996,-0.025057726000000002,0.046671052000000005,0.016532948999999998,-0.002839675,-0.098409958,0.002808605,-0.103699025,-0.06493552799999999,1.516860251,2.383603024,-1.7020147230000002,-1.373267403,-2.575764549,-2.7128791810000004,-0.798187286,-1.049975197,-1.7272857659999998,-0.850259095,-4.3492937088012695,-4.074180603027344,-3.6392598152160645,-3.517040491104126,-4.0219268798828125 -4807,4807,E277C,-0.023354652000000004,0.015238709,0.011278123000000001,-0.069879971,-0.6154974639999999,0.02866313,0.053307966,-0.10001727,0.07734085,0.007183928000000001,0.02329349,0.0067164780000000006,0.015839768,-0.11366428099999999,-0.026095661000000003,-0.440974436,-0.7900204909999999,1.345469034,1.7749629519999999,-7.9448334460000005,-7.408907982000001,-9.013990585,-9.170588043,-6.423676826,-7.707003792,-7.74544551,-7.230363313,-9.520374298095703,-9.067087173461914,-10.39278793334961,-9.338089942932129,-11.164712905883789 -4808,4808,E277D,0.041215275,0.0014623779999999999,0.002400105,-0.08024479999999999,-0.061959965,0.034811556,0.097130475,-0.014699926,0.04364712,-0.09314338,0.096068135,-0.044348494,0.049148702999999995,-0.154193197,-0.006296403000000001,-0.124601481,0.0006815510000000001,1.4676791569999998,2.2686011180000003,-0.787553625,-0.810155525,-1.127179634,-0.161002258,-0.7888090440000001,-1.0506216659999998,-1.497576332,-0.478717435,-4.462655067443848,-4.0661821365356445,-3.895084857940674,-4.5992326736450195,-4.405995845794678 -4809,4809,E277G,0.015894186,0.032356931,0.029230847,-0.005202324,-0.146375894,0.013446301,0.075869963,-0.044081592,-0.0016483429999999998,-0.00836555,0.073079411,0.022096595,0.036365099,-0.049628395,0.039223747999999996,-0.13804624599999998,-0.154705542,1.498467606,2.311117238,-1.4636720019999998,-2.09456488,-1.555823067,-2.385668076,-0.591078323,-0.691225662,-1.303547332,-2.314396311,-6.229880332946777,-5.642017841339111,-5.7184319496154785,-6.148513317108154,-5.614445686340332 -4810,4810,E277F,-0.017330263999999998,-0.015818521000000002,-0.001955407,-0.047509547,-0.9709960059999999,0.023187961,0.04503544,-0.079695967,0.059023708,-0.06838168,0.036744638999999996,-0.047610789,0.043699975,-0.10843792699999999,0.013418834,-0.664691444,-1.277300568,1.3541706430000002,1.640203979,-7.78295049,-7.131377991,-8.803028557000001,-8.818500336,-5.999906975,-8.161938591,-6.088351667,-4.501029945,-7.952647686004639,-8.459882736206055,-8.662374496459961,-8.593942642211914,-9.549013137817383 -4811,4811,E277I,0.02674516,0.052386546,0.082034817,-0.011727811000000001,-0.01757013,0.027342504,0.083245793,-0.029755474,0.028970051,0.070982217,0.033790875,0.11221104900000001,0.051858585,-0.033378472,0.00992285,0.048705822,-0.083846082,1.097952375,2.666035962,-7.15067252,-6.429479706,-8.461775719,-8.250545623999999,-5.630901375,-6.980660179,-5.850008074,-5.066813212,-6.991881847381592,-7.293046474456787,-6.939253807067871,-6.068655967712402,-8.052369117736816 -4812,4812,E277H,0.016540236,0.028481397999999998,0.027761926,-0.013478223999999999,-0.333711473,-0.014119486,0.058862455999999994,-0.025781983999999997,0.040991694,-0.023497628,0.080460423,0.001921925,0.053601927,-0.069117213,0.042160765,-0.25739284,-0.410030105,1.5186933980000001,2.092570334,-5.512467914,-5.1713074489999995,-6.5163707429999995,-6.496917037999999,-4.2391287460000004,-5.138615593,-4.387670697,-2.9018341860000003,-6.929948329925537,-6.451454162597656,-6.774991035461426,-7.023861885070801,-6.6287994384765625 -4813,4813,E277K,-0.0022668379999999998,0.055085321,0.0013251970000000002,-0.039372177,-0.144432723,0.006487571,0.047720422,-0.052254097,0.063334585,0.014966408999999998,0.09520423300000001,-0.030036887,0.032687281,-0.070155306,-0.008589046999999999,-0.11294447199999999,-0.175920973,1.4928048580000002,2.390099507,-2.438361826,-2.092287849,-3.122086487,-3.958044182,-1.105299278,-1.9140913309999998,-2.528163857,-0.907644096,-6.060030937194824,-5.832945823669434,-5.421319007873535,-5.219460487365723,-5.761620044708252 -4814,4814,E277M,-0.002316351,-0.019171449,0.011471608000000001,-0.008560809,-0.253701899,-0.016115138,0.057490763,-0.062123465,0.06617192,-0.022979515,-0.015363382,0.003998208,0.018945008,-0.046405735999999996,0.029284117999999998,-0.216424903,-0.290978894,1.467410869,2.128036376,-6.61972942,-6.0247078929999995,-7.951825562000001,-7.861085602,-5.205350021,-6.055678024,-5.511907997000001,-4.668250237,-6.959402084350586,-6.825348377227783,-7.1102190017700195,-6.21719217300415,-7.477293491363525 -4815,4815,E277L,-0.005365258,0.030166009,0.0342485,-0.0046235,-0.07440751599999999,0.0050975659999999996,0.041512403999999996,-0.05224292,0.029298435,0.023745141,0.036586877000000004,0.034587132,0.033909867999999996,-0.050821065,0.041574066,-0.047742792,-0.10107224,1.318882223,2.493946148,-5.88575791,-5.366078186,-7.516418495,-7.2419723739999995,-3.872319862,-5.4320006329999995,-4.950276888,-3.215516136,-5.413522720336914,-5.847283840179443,-5.595296859741211,-4.924929618835449,-6.469933986663818 -4816,4816,E277N,-0.057248497999999995,0.030892616,-0.008512259,-0.050059604,-0.077807463,0.017271898,0.015655126999999998,-0.130152123,0.053122975,0.058609412,0.0031758190000000003,0.045469067,-0.062493585,-0.083196358,-0.016922849,-0.022119609,-0.133495317,1.276755325,2.5206573519999997,-3.571744055,-3.095841568,-3.8727821039999997,-4.402131607,-2.805825874,-3.6821391219999997,-4.031186585,-2.30439738,-6.285928726196289,-5.466135501861572,-5.4861979484558105,-6.10498046875,-5.758358001708984 -4817,4817,E277Q,0.052980545999999996,0.05491105,0.047420889,-0.015463111000000002,-0.046492212000000005,-0.0052483930000000005,0.120838869,-0.014877777,0.038516378999999996,0.017216727,0.09260537199999999,0.031468465,0.063373312,-0.042786448,0.011860226000000001,-0.047231612,-0.045752811,1.2110845,2.347432485,-2.6200011919999997,-1.780935944,-3.854248985,-3.691290825,-1.610403709,-2.163126495,-2.827270372,-0.8676208320000001,-4.963591575622559,-4.739258289337158,-4.419134616851807,-3.9567811489105225,-4.3377180099487305 -4818,4818,E277P,-0.038016095,-0.01238717,-1.066721951,-2.016079391,-2.622383871,-0.005143305999999999,0.034958381000000004,-0.11099057,0.035336322999999996,-0.014713671999999999,-0.010060666999999999,-0.8431897740000001,-1.290254128,-1.989312446,-2.0428463359999998,-2.389361708,-2.855406033,1.983872644,0.821750433,-7.379614151,-6.668447258,-8.614418144,-8.427169082999999,-6.2050398179999995,-6.982996452,-6.7967149860000005,-6.379811591,-8.853391647338867,-7.473248481750488,-8.975077629089355,-9.177558898925781,-10.725332260131836 -4819,4819,E277S,-0.0015054629999999999,0.024718659,0.026446672,-0.018985389,-0.123684104,0.011604761000000002,0.047373387999999995,-0.050384314000000006,0.033215354,0.004082055,0.045355263,0.030914627000000004,0.021978717000000002,-0.054125812999999995,0.016155035,-0.100494319,-0.146873888,1.4166213269999999,2.308803801,-2.628682588,-2.102047646,-3.711332954,-3.686816696,-1.187179756,-2.4560358890000002,-3.291112973,-1.4658489469999998,-5.4273271560668945,-5.0152788162231445,-5.233918190002441,-5.389951229095459,-5.194364547729492 -4820,4820,E277R,0.015267132,0.019348055,0.026553127000000003,-0.028979583,-0.086642792,0.015111665,0.06622819099999999,-0.035693927,0.012924911,-0.021498694,0.060194803,0.019735393,0.033370861,-0.080208066,0.022248900000000002,-0.10699598800000001,-0.06628959599999999,1.360625206,2.27497444,-2.9439990839999997,-2.73182634,-4.697427536,-3.849660469,-1.6468047559999999,-1.794276321,-2.733408077,-0.743203059,-6.1122894287109375,-6.185584545135498,-5.878171920776367,-5.516201019287109,-5.791182518005371 -4821,4821,E277T,-0.001347203,0.026787441000000002,0.035428137,-0.026144112999999997,-0.10085090199999999,0.029270477000000003,0.050442532000000005,-0.053136937999999995,-0.007021241,-0.03967362,0.093248501,0.010674177,0.060182097000000004,-0.102839091,0.05055086599999999,-0.13447388,-0.06722792400000001,1.3845516969999998,2.18563951,-3.5338443760000002,-3.272731133,-4.000649994,-4.580359436,-2.17082708,-3.644654236,-3.316163995,-1.885857704,-5.624759197235107,-5.1378631591796875,-4.973543167114258,-4.812265396118164,-5.310413360595703 -4822,4822,E277W,-0.026001196,-0.007137312,-0.016372995,-0.044038305,-1.5297713590000002,-0.006538233,0.017627132,-0.069629524,0.021208187000000003,-0.050581665,0.036307041,-0.045208881,0.012462892,-0.08564373300000001,-0.002432877,-1.311807809,-1.7477349080000002,0.9757278640000001,1.362554649,-8.852678394,-8.081930473,-10.37750714,-9.884582161,-7.319036278,-8.600335915,-7.47587962,-6.7067509020000005,-8.617796897888184,-8.964942932128906,-9.29251480102539,-9.96746826171875,-9.812936782836914 -4823,4823,E277V,0.007497515,0.025001303,0.036874386,-0.025952249,-0.169901523,0.019783886,0.074956539,-0.05996151,0.028857715,-0.005515464,0.055518069,0.030579073,0.043169699000000006,-0.082253906,0.030349407999999998,-0.149402741,-0.190400304,1.544053338,2.281105729,-6.199258553,-5.73860424,-7.461063789,-6.930171829,-4.716852974,-6.14959993,-5.638574747000001,-4.352475737,-6.520524978637695,-6.333583831787109,-6.105135917663574,-5.401129722595215,-7.169701099395752 -4824,4824,E277Y,0.073440804,0.099287529,0.06351747,-0.007164806,-0.677625439,0.030940656,0.152797864,-0.005916256999999999,0.052870798,0.045753694000000004,0.15282136300000002,0.029339566,0.097695374,-0.067293639,0.052964027999999996,-0.515316505,-0.839934373,1.082772004,1.58018952,-8.321023488,-8.02440509,-9.050229919,-9.376322815,-6.453161781,-8.700997832999999,-6.661261153,-5.576851957000001,-8.441326141357422,-8.3226957321167,-8.928445816040039,-9.071088790893555,-9.222768783569336 -4825,4825,I278A,0.056076494000000005,0.028877332999999998,-0.905099745,-2.035603059,-2.41015192,-0.07566700400000001,0.066785317,0.04536767,0.027280596,0.07314870700000001,-0.015394041,-0.601011448,-1.209188042,-1.980647338,-2.090558779,-2.255627176,-2.564676663,1.3774376730000002,0.673649424,-9.569987471000001,-9.122805,-8.532033669,-12.10747746,-8.440510848999999,-9.647110382000001,-5.048038636,-0.252753314,-5.870149612426758,-6.181903839111328,-5.060521602630615,-7.017568588256836,-8.49726676940918 -4826,4826,I278C,0.065918774,0.035751885,-0.059023067,-1.5770732969999999,-2.724411475,-0.036649747,0.09932791199999999,0.032509635,0.06572196599999999,0.030089087999999996,0.041414682,0.052336402000000004,-0.170382535,-1.563238011,-1.590908582,-2.450037677,-2.998785273,0.585040879,0.693055455,-11.93246632,-10.99329163,-13.01908903,-14.849301,-11.38590974,-9.414740189,-7.404019872999999,-4.375159422,-10.072774887084961,-9.248222351074219,-8.551645278930664,-11.083612442016602,-11.850855827331543 -4827,4827,I278E,0.062813934,-1.417552949,-1.7368482669999998,-2.11235497,-2.768557532,0.002203827,0.08518151,0.040446357,0.096017496,-1.311130323,-1.523975575,-1.767665047,-1.706031487,-1.919180678,-2.305529262,-2.629889085,-2.9072259789999997,3.822299005,1.6798396009999998,-14.74915459,-14.383946700000001,-15.16718099,-16.8797562,-13.77609933,-13.53878972,-9.977288552000001,-9.693275619,-11.587833404541016,-10.824871063232422,-10.18934440612793,-14.110694885253906,-12.720335960388184 -4828,4828,I278D,0.032391768,-1.8450947530000001,-2.244240492,-2.150821148,-2.7189780810000004,-0.003324025,0.072799848,-0.008016312,0.0183429,-2.177111928,-1.5130775769999998,-2.156525397,-2.331955587,-2.3080410280000003,-1.9936012680000001,-2.541628181,-2.896327981,-0.704536803,-1.130024621,-15.01972886,-14.64855177,-15.67748311,-17.58568492,-13.66431274,-13.52261175,-9.977288552000001,-9.693275593,-12.42435359954834,-12.20484447479248,-10.20183277130127,-14.348369598388672,-14.801631927490234 -4829,4829,I278G,0.045045383,-1.397642504,-1.981529313,-2.1683006209999998,-3.270264765,-0.025708788,0.079393975,0.010696791,0.065685841,-1.3720305640000001,-1.423254443,-1.870688493,-2.0923701319999997,-2.087144931,-2.24945631,-3.511063783,-3.029465746,-0.8733494340000001,-1.111130082,-14.94687464,-14.55639507,-15.22080136,-17.83537323,-13.61082409,-13.51097946,-8.996816221,-6.773250018,-10.998559951782227,-10.259455680847168,-9.294288635253906,-12.394499778747559,-13.875650405883789 -4830,4830,I278F,0.075004417,-0.028025586,0.06614773,-1.197257717,-2.779089453,-0.08695760400000001,0.107313311,0.042695523,-0.107637106,-0.06781084799999999,0.011759677,0.022225618,0.11006984199999999,-0.585527703,-1.808987731,-2.670373204,-2.887805702,0.813131357,0.847523415,-10.23249992,-9.626586319,-10.85892978,-11.46787797,-9.776989151,-9.432116402,-6.963039209,-4.431209841,-6.65791654586792,-6.881344318389893,-6.833320617675781,-7.951846122741699,-7.688119411468506 -4831,4831,I278H,0.022980293,-1.1288702259999999,-1.750135979,-2.2481819769999998,-2.801357298,-0.024986418,0.067765057,-0.021804472000000002,0.069690439,-1.1274859259999999,-1.130254525,-1.58402065,-1.916251308,-1.7935282280000002,-2.7028357260000004,-2.395092166,-3.20762243,3.836518748,1.907514691,-15.10958502,-13.90549351,-16.17165051,-17.87835545,-13.72857601,-13.86384961,-9.977288552000001,-9.693275573,-12.190237998962402,-10.877960205078125,-9.958290100097656,-14.238385200500488,-13.098089218139648 -4832,4832,I278K,0.028567112000000002,-1.668862871,-1.806569238,-2.324074269,-2.392231202,0.028536968,0.065829579,-0.008695356,0.002722858,-1.411025189,-1.9267005519999998,-1.867559913,-1.745578562,-2.019075544,-2.6290729930000003,-2.252662697,-2.531799706,-0.30948849300000003,-0.856612659,-14.0848083,-13.59405472,-14.71755333,-16.05938984,-12.58090678,-13.47213683,-9.977288552000001,-9.693275584,-13.303421020507812,-10.185285568237305,-10.351675033569336,-14.884025573730469,-14.003783226013184 -4833,4833,I278M,0.069461297,0.049382435999999995,0.027597952000000002,0.035536512,-0.522765186,-0.06749736099999999,0.1080133,0.030909292999999997,-0.095063632,0.069080919,0.029683952000000003,0.003186965,0.052008938,0.010238248,0.06083477599999999,-0.326693028,-0.7188373440000001,1.040272799,1.684636361,-6.402777736,-6.337168297000001,-7.415621361,-7.194451614,-5.821820992,-5.244826416,-5.7505353779999995,-3.092388428,-6.018010139465332,-5.068363666534424,-6.433677673339844,-7.6039347648620605,-7.501511573791504 -4834,4834,I278L,0.02015708,-0.006131221,0.042032731,0.042220060999999996,-0.61840592,-0.023898532000000004,0.035174343999999996,0.005139815,0.028627474,0.028711251,-0.040973692,0.066075192,0.017990269,0.045062612,0.03937751,-0.40022498,-0.8365868590000001,0.848657977,1.542419891,-3.757869556,-3.94019812,-4.591186295,-4.456968964,-2.92995623,-2.87103817,-2.9045365839999997,-1.260680654,-4.54917573928833,-3.8803300857543945,-4.017966270446777,-4.872528076171875,-4.730185508728027 -4835,4835,I278N,-0.0036913959999999996,-1.383026415,-1.481142159,-2.450192183,-2.518349116,-0.09559506699999999,0.002771456,-0.010154248000000001,0.055595360999999996,-1.5019448380000002,-1.264107992,-1.356419571,-1.6058647469999998,-2.109995193,-2.7903891730000003,-2.343582346,-2.693115886,3.337052772,1.280878699,-14.32874286,-13.52383824,-15.44965825,-16.9105555,-13.268068300000001,-12.491594000000001,-9.977288552000001,-9.693275553,-12.075638771057129,-11.793667793273926,-10.458170890808105,-14.011033058166504,-14.333112716674805 -4836,4836,I278Q,0.03504747,-0.938294285,-2.106349572,-2.198735763,-2.8821171569999997,-0.080533878,0.052638227999999995,0.017456711,0.12437637900000001,-0.640734687,-1.2358538829999999,-2.352541916,-1.860157228,-2.504057547,-1.893413979,-2.7376447,-3.026589613,0.334101503,-0.536750225,-14.0307673,-13.78402149,-14.70478193,-16.45904272,-12.11251338,-13.09347699,-9.977288552000001,-9.693275571000001,-11.677441596984863,-10.515413284301758,-9.306127548217773,-13.936321258544922,-12.428683280944824 -4837,4837,I278P,0.033718616,-1.418717578,-1.9494840340000001,-2.3540861140000002,-2.732630383,-0.02038558,0.060098527,0.007338705,0.038612642,-1.350296036,-1.487139119,-2.0286795090000003,-1.870288559,-2.282857482,-2.4253147459999997,-2.6511432090000002,-2.8141175560000002,0.128680822,-0.821789707,-14.86634902,-14.35851046,-15.09696471,-17.30838338,-13.78354916,-13.78433737,-9.977288552000001,-9.693275599,-13.136296272277832,-12.775486946105957,-11.871479988098145,-14.747133255004883,-15.96955394744873 -4838,4838,I278S,0.052937463,-0.88193843,-1.978042302,-1.8196572290000002,-2.9043248839999998,-0.045775202,0.084024376,0.021850549,0.067296853,-0.514962814,-1.248914045,-2.177423321,-1.7786612819999998,-1.9139656040000002,-1.7253488540000002,-2.562526105,-3.246123663,0.628439515,-0.438363358,-11.86347583,-10.903396800000001,-12.76568087,-14.49189594,-10.86150108,-10.29490448,-6.5798735079999995,-3.81254783,-9.515251159667969,-9.748673439025879,-8.631653785705566,-11.234346389770508,-12.189542770385742 -4839,4839,I278R,0.060562940999999995,-1.534849795,-1.8645005430000001,-2.115274629,-2.68954879,-0.033131503,0.08398932099999999,0.037136561,0.024460082999999997,-1.497266576,-1.5724330130000002,-1.693389155,-2.035611931,-1.9961724619999999,-2.234376796,-2.609970856,-2.769126724,3.648520262,1.3990449969999998,-14.57268063,-14.40202109,-15.02070216,-16.8340152,-12.96193227,-13.64473245,-9.977288552000001,-9.693275551000001,-13.050271034240723,-10.180316925048828,-10.000362396240234,-14.758630752563477,-14.038216590881348 -4840,4840,I278T,-0.026246092000000002,0.000783217,-0.39724831299999996,-1.66426204,-2.2320846430000003,-0.052512998,0.024446786,-0.07693897,0.062830223,0.078464543,-0.07689811,-0.066842835,-0.7276537909999999,-1.6766528630000002,-1.651871216,-2.252662697,-2.211506588,0.823540921,0.6979712309999999,-7.864695319,-7.1918115689999995,-7.531070327999999,-8.079557076,-8.162893578,-8.358144043,-4.445008803,-1.800922685,-7.047465801239014,-6.885941505432129,-6.255902290344238,-7.614860534667969,-8.946501731872559 -4841,4841,I278W,0.028259215,-0.058341937,-1.059824487,-1.756913837,-2.9586566339999996,0.004918201,0.08644029800000001,-0.029921867999999997,0.017499161000000003,-0.028113709,-0.088570164,-0.774270413,-1.34537856,-1.8800285540000001,-1.63379912,-2.812585711,-3.104727557,2.0155219140000002,0.882050157,-13.88598817,-13.4723839,-14.63556781,-15.63789467,-13.05714108,-12.6269534,-9.977288552000001,-9.693275597000001,-10.312189102172852,-9.539118766784668,-10.018179893493652,-13.368226051330566,-12.455942153930664 -4842,4842,I278V,0.051657167999999996,0.033056886,0.05060728900000001,0.014369836,-0.232038281,-0.01799932,0.061227442,0.042086893,0.08628676699999999,0.05857877400000001,0.007534997,0.053344214,0.047870364000000006,0.044035662999999996,-0.015295991,-0.174275784,-0.289800778,1.253981014,2.066721783,-3.526197812,-3.294229965,-2.49047261,-4.6774621960000005,-3.2580514369999998,-3.91077285,-4.5571100410000005,-0.20912949600000003,-3.997148036956787,-3.8288707733154297,-3.8224220275878906,-3.7623071670532227,-4.072354793548584 -4843,4843,I278Y,0.049432917,-0.672297378,-1.949380546,-2.5064762000000003,-2.5746331330000003,0.042156168,0.131059685,-0.032193852,0.063598026,-0.325853579,-1.018741177,-1.58402065,-2.3147404419999997,-2.036566276,-2.976386123,-2.270153429,-2.8791128360000005,3.799390638,2.094074671,-13.12294019,-12.39918124,-14.34595773,-14.60875337,-12.29360677,-11.96720184,-8.970978559,-6.618413068,-9.71701431274414,-8.835424423217773,-9.300604820251465,-11.902581214904785,-10.633973121643066 -4844,4844,G279A,0.035083303999999996,-0.032186025,-0.013159029,-0.0032020190000000004,-0.144679187,-0.069718238,0.037740699999999995,0.032425907000000004,-0.001010239,-0.037498792999999996,-0.026873256,-0.018709422,-0.007608635999999999,0.003637809,-0.010041847,-0.149199212,-0.140159162,1.452302797,2.2741593769999997,-4.3991343480000005,-4.91506012,-4.970529839,-4.7851548919999995,-3.18550975,-4.139417137,-4.7831819289999995,0.564551247,-4.075818061828613,-5.556670188903809,-4.651618957519531,-3.5443553924560547,-6.776238441467285 -4845,4845,G279C,0.03151748,-0.026482436,0.013056864,0.033366771,-1.062366435,-0.126928682,0.046972720999999995,0.016062239,-0.032333613,-0.007090698,-0.045874174000000004,-0.03903644,0.065150167,0.076900598,-0.010167055999999999,-0.9779716999999999,-1.14676117,0.610259045,1.348010358,-11.84284135,-12.67624622,-12.39539081,-13.47169671,-10.15562521,-10.515247800000001,-9.15576674,-5.980533335,-8.755387306213379,-9.06855297088623,-8.242148399353027,-8.354799270629883,-10.966531753540039 -4846,4846,G279E,0.005416384000000001,0.012067668,-0.878178737,-1.935768219,-2.340217753,-0.115251514,0.013305576999999999,-0.002472809,0.058230635999999995,-0.09380864,0.117943975,-0.47645947299999997,-1.2798980009999998,-1.736215541,-2.1353208969999997,-2.058966791,-2.621468714,3.25636845,2.088183917,-12.38293445,-12.69776743,-12.45172106,-14.22418253,-11.17755183,-11.36344942,-10.58585342,-9.379787925,-9.543272018432617,-11.78338623046875,-11.348429679870605,-11.129688262939453,-14.680171012878418 -4847,4847,G279D,-0.029044134,-0.8545739440000001,-2.063879468,-2.4362256230000003,-2.457716759,-0.012036937,0.049457115,-0.10754538300000001,-0.000569711,-0.47751612,-1.231631767,-1.969730828,-2.158028107,-1.8831339219999998,-2.9893173230000003,-2.586096414,-2.329337104,3.447923629,1.555061337,-11.772696400000001,-11.92055965,-12.26712797,-13.44915276,-10.60490658,-10.62173504,-9.673791891,-6.710562507000001,-9.967187881469727,-12.528382301330566,-11.851975440979004,-11.82983684539795,-15.627805709838867 -4848,4848,G279F,0.045047277999999996,0.015083473,0.051430795999999994,-0.7164667370000001,-2.0084977569999998,-0.18796916,0.035834656,0.05425990000000001,-0.047112545,-0.031159642999999997,0.061326588,-0.00450867,0.107370262,-0.481933241,-0.9510002320000001,-1.827250319,-2.189745194,1.675264696,1.419853703,-13.09671808,-14.17227074,-13.78717834,-14.08385156,-11.71718905,-11.72310072,-9.610975058,-6.535952267000001,-11.152589797973633,-13.920886039733887,-10.661964416503906,-12.308012008666992,-15.817642211914062 -4849,4849,G279I,-0.010072221999999999,-0.099754063,-0.051053203,-0.646870635,-1.940218459,-0.131474791,0.018001295,-0.038145738,0.050343407,-0.022823671,-0.176684455,0.010181583000000001,-0.112287988,-0.236220713,-1.0575205570000001,-1.6503876659999999,-2.230049251,1.379284386,1.383938149,-13.88539047,-15.59617775,-13.68665834,-16.44673135,-11.69564648,-12.00173843,-9.079843102,-6.318015759,-9.862384796142578,-11.169838905334473,-9.978201866149902,-10.437819480895996,-13.38321304321289 -4850,4850,G279H,0.015607238999999998,-0.025921147000000002,-0.559668554,-1.859004136,-2.631557034,-0.076138964,0.028232437000000003,0.00298204,-0.041414129,-0.056268092,0.004425799,-0.301029996,-0.818307111,-1.76075137,-1.957256902,-2.7269552960000003,-2.536158772,1.4244761830000001,0.7574418009999999,-13.10324638,-13.57627797,-13.78960477,-14.06519797,-11.88680075,-12.19835043,-10.59389423,-9.402820286,-10.847747802734375,-12.246649742126465,-10.971920013427734,-14.078197479248047,-16.417560577392578 -4851,4851,G279K,-0.016716695,-0.620964551,-2.128942205,-2.390363985,-2.47432449,-0.08934065599999999,0.100956735,-0.134390125,-0.032263424,-0.427168592,-0.8147605090000001,-2.037482612,-2.220401797,-2.126976965,-2.653751005,-2.352818202,-2.5958307769999998,1.2099324759999999,-0.13442447,-13.06173776,-13.51913237,-13.06761275,-15.00838102,-11.62739579,-12.08616689,-10.59389423,-9.402820286,-13.141857147216797,-13.180181503295898,-12.699049949645996,-12.908487319946289,-15.169988632202148 -4852,4852,G279M,-0.04877950599999999,-0.00516402,-0.006060875,-0.29554102,-1.7132280009999998,-0.132425574,-0.004543443,-0.093015568,-0.013589511,0.023011035,-0.033339075,0.049626002,-0.061747752,-0.020124293,-0.570957746,-1.422056789,-2.004399212,0.45351015100000003,1.312111566,-11.3868215,-12.84522128,-9.721073952000001,-14.39895261,-9.435954062999999,-10.53290557,-7.464215918,-4.4819620030000005,-9.058791160583496,-11.866109848022461,-9.773811340332031,-10.166260719299316,-13.446032524108887 -4853,4853,G279L,0.023121024,-0.034256785,0.01195786,-0.590287792,-1.7301822119999999,-0.16306207,-0.012345206999999999,0.058587254000000005,-0.030122668999999998,-0.049674864000000006,-0.018838705,-0.027921127999999996,0.051836848,-0.361655503,-0.8189200809999999,-1.668981941,-1.791382482,1.56996557,1.4314362330000001,-14.18848948,-15.27959137,-13.71591731,-17.07220944,-12.41383508,-12.4608942,-10.52752701,-8.935342308,-10.18332290649414,-12.335351943969727,-9.841267585754395,-11.040875434875488,-13.919861793518066 -4854,4854,G279N,-0.0688805,0.007207674,-0.09067189199999999,-1.404416954,-2.428784255,-0.000829236,0.057179403,-0.194940403,-0.075757726,-0.072694277,0.08710962400000001,-0.112342484,-0.069001299,-1.303068224,-1.505765684,-2.130969453,-2.726599057,2.40748187,1.541304139,-11.74133575,-12.73100261,-11.60441441,-13.454812699999998,-10.8548148,-10.06163426,-9.611257592000001,-6.712529404,-8.767725944519043,-11.059639930725098,-9.25279712677002,-11.018980026245117,-14.140839576721191 -4855,4855,G279Q,-0.000674041,0.008410374,-0.329597648,-1.821198371,-2.624825223,-0.074202246,0.022672906,-0.024020987999999997,-0.064353979,-0.04616423,0.062984978,-0.225622729,-0.433572567,-1.536175487,-2.106221255,-2.502379414,-2.7472710310000004,1.339068178,0.774209275,-12.27831988,-12.74825313,-12.2106631,-14.43006277,-10.91652138,-11.08609903,-10.02683485,-7.364347617000001,-10.916516304016113,-12.719945907592773,-10.950599670410156,-13.24752426147461,-15.377936363220215 -4856,4856,G279P,0.015901238999999998,-0.83331947,-1.94945741,-2.078344168,-2.7982254760000003,-0.063610445,0.011869478000000001,0.019933000000000003,0.026474935,-0.637747713,-1.028891226,-2.052586975,-1.8463278440000002,-2.054931153,-2.101757182,-2.79928633,-2.7971646210000003,1.4430964569999998,-0.13670242400000002,-12.68594377,-13.174462300000002,-12.68875695,-14.235978,-11.41814249,-11.91237912,-9.618949954,-6.709987607,-12.843277931213379,-13.212440490722656,-12.290573120117188,-12.586639404296875,-15.267829895019531 -4857,4857,G279S,0.003946601,-0.025150499,-0.016562023000000002,0.016438826,-0.343477982,-0.066889618,-0.010367531999999999,0.018260733,-0.020194877,-0.041025057999999996,-0.00927594,-0.040134222000000004,0.007010176999999999,0.021495393999999998,0.011382258000000001,-0.28901181800000003,-0.397944145,1.213425211,1.836332496,-5.6218242720000005,-6.443435622999999,-6.837715508,-6.886850807,-4.425131218,-3.515988205,-5.562993167,-0.104864469,-4.766536235809326,-6.602413177490234,-5.359592437744141,-5.745476722717285,-7.769841194152832 -4858,4858,G279R,-0.033398582999999996,-0.5654163320000001,-1.889226946,-1.9987098069999998,-2.726890745,-0.028573312000000003,-0.018602143,-0.048195023,-0.007219631,-0.285756944,-0.84507572,-1.93142922,-1.847024671,-1.844832314,-2.152587299,-2.496642283,-2.957139207,1.095507857,-0.06830159,-12.08705377,-12.552339300000002,-12.35028331,-14.34890885,-10.25864632,-10.92509108,-9.373243636,-6.318015742,-12.369335174560547,-10.25294303894043,-10.834723472595215,-11.784360885620117,-14.915325164794922 -4859,4859,G279T,0.014495283000000001,-0.024648527000000003,-0.012319446999999999,0.019491731,-1.678160555,-0.111023804,-0.008623725,0.03761429,-0.013559612,-0.022746456,-0.026550597999999998,-0.025158877000000003,0.000519983,0.06579033599999999,-0.026806875,-1.6639653319999999,-1.692355777,0.5711923329999999,1.30799748,-8.105794716,-9.183267929,-7.00078318,-11.76880763,-6.2183761220000004,-6.357738716,-6.148769525,-0.726459904,-5.371004581451416,-6.1713762283325195,-6.0814595222473145,-5.690719127655029,-8.872608184814453 -4860,4860,G279W,0.029707326000000003,-0.024021487999999997,-0.08026768299999999,-1.537666186,-2.295020434,-0.18865384300000002,0.034229827000000004,0.025184823999999998,0.006363301,-0.021740562,-0.026302412999999997,0.003738381,-0.164273747,-1.3303423090000002,-1.7449900630000001,-2.459273533,-2.130767334,0.70397686,0.718568823,-13.79455441,-14.27525241,-14.38844505,-15.64309074,-12.16962045,-12.49636343,-10.59389423,-9.402820286,-13.457633972167969,-16.149341583251953,-13.96743392944336,-15.42573070526123,-17.660093307495117 -4861,4861,G279V,0.020557686000000002,-0.004060423,-0.003508372,-0.456489365,-1.91550309,-0.187586318,0.029302545,0.011812826,-0.057438011,-0.021187125,0.01306628,-0.035848659,0.028831916000000003,-0.218384964,-0.694593765,-1.8486322519999998,-1.9823739269999998,1.239326325,1.340229511,-10.80466221,-11.71678468,-11.21245773,-13.6775176,-8.154507042,-9.262043968,-6.701905238999999,-2.8401942160000004,-8.435967445373535,-8.172161102294922,-7.624216556549072,-7.349998474121094,-11.303792953491211 -4862,4862,G279Y,-0.025694175,-0.007533051999999999,-0.041436918999999996,-1.39304885,-2.126980805,-0.249950124,-0.09422345300000001,0.042835104000000006,-0.012657035,-0.0056921459999999995,-0.009373958,-0.066395546,-0.016478291000000003,-1.5756096819999998,-1.210488017,-1.947578955,-2.306382654,3.137502062,2.144082874,-13.62306969,-14.00416248,-14.84832811,-14.59426494,-12.34747366,-12.32111926,-10.33023528,-7.961943686000001,-11.922821044921875,-13.774547576904297,-12.222944259643555,-14.852705001831055,-17.273860931396484 -4863,4863,A280C,-0.012123014,0.005180578,0.006360944,0.026847236,-0.42295384399999997,-0.04859699,-0.050141592,0.025895565,0.04235680000000001,0.016852827,-0.0064916719999999995,0.024187019,-0.011465132,0.038886317999999996,0.014808153000000001,-0.243557561,-0.602350126,1.132350998,1.834234278,-7.138248729,-6.5515447689999995,-7.66185553,-7.636461402999999,-7.396858025,-6.444523918,-8.578425567,-8.166355106000001,-9.223932266235352,-8.216670989990234,-8.651044845581055,-8.228015899658203,-6.970437049865723 -4864,4864,A280E,-0.068131829,-0.010652531000000002,-0.044225234,-0.023658127999999997,0.017609574,-0.004638617,-0.077869781,-0.058393877000000004,0.002337956,0.040451276,-0.061756338,-0.01731095,-0.071139517,0.019574082,-0.066890338,0.07909559,-0.043876443,1.075653676,2.805858865,-1.431726546,-0.897412155,-2.161764984,-1.325609276,-1.861209862,-0.912636452,-2.558286352,-0.310539899,-4.807412147521973,-5.2274088859558105,-4.006538391113281,-5.228678226470947,-4.349738597869873 -4865,4865,A280D,-0.060825261,0.079135888,0.012624161000000002,0.02748281,0.0026237979999999997,0.012943793,-0.02575471,-0.095895812,0.045115712999999995,0.11376284,0.044508935,0.079243719,-0.053995398,0.127950798,-0.072985178,0.031826022999999995,-0.026578427,1.054305364,2.766293118,-2.959758578,-3.1637553560000002,-2.8032171630000002,-3.156321953,-2.9573259430000003,-2.718172478,-3.69589031,-2.748780747,-7.563338279724121,-7.047604084014893,-5.590389251708984,-7.535494327545166,-6.885301113128662 -4866,4866,A280G,-0.028084208,0.032488889,-0.009374351,-0.004871993,-0.030074452999999998,-0.02445038,-0.06793450599999999,0.011766091000000001,0.006655706999999999,0.057650043,0.007327735,-0.004435183,-0.014313518999999999,-0.001137383,-0.008606602,-0.014858978,-0.045289927,1.361151851,2.6363844690000002,-2.699690225,-2.382833427,-3.141731659,-2.0860739440000002,-3.382511063,-2.5053010330000003,-4.430067201,-1.824280479,-5.599696636199951,-5.376977920532227,-4.890018463134766,-5.259400844573975,-4.421778202056885 -4867,4867,A280F,-0.0033699109999999997,0.09971469300000001,0.000668165,0.042391037,-0.02941169,0.016562666,-0.084948933,0.078209112,0.062382738,0.105636219,0.093793166,0.013668392,-0.012332063,0.039626173,0.045155900000000006,-0.021671094,-0.037152285,1.284620528,2.631746913,-7.264147266,-6.339791618,-7.788956841,-8.125723488,-7.9400709460000005,-6.126193436,-6.772227335,-3.779980548,-8.631471633911133,-8.764963150024414,-7.881493091583252,-7.9614667892456055,-7.588431358337402 -4868,4868,A280I,-0.090391735,0.034865863,-0.080872316,0.006725180999999999,-0.036654566,0.037384397,-0.102210428,-0.078573041,0.165819234,0.066449324,0.0032824020000000002,-0.052252757000000004,-0.109491874,0.048984495999999995,-0.035534135,-0.013861428,-0.059447704000000004,1.222799075,2.6091865569999997,-6.331086253,-5.841335213,-7.811389709,-5.750956497000001,-7.054577637,-5.197172211,-6.381855316,-4.438068099,-7.279677391052246,-7.516753673553467,-6.864455223083496,-6.63908052444458,-6.176238059997559 -4869,4869,A280H,-0.012493345,0.038923493999999996,-0.032212807999999996,0.015057306000000001,-0.00561883,-0.078405741,-0.052569378,0.027582687999999998,0.011639449,0.07594698799999999,0.0019,-0.00655758,-0.057868036,0.065331573,-0.035216961,0.048224166,-0.059461825,1.211130532,2.9389808389999996,-3.784533521,-3.2129159389999997,-4.17752282,-4.200681366,-4.24639418,-3.0851532969999997,-4.418092198,-2.1934723309999997,-6.955475807189941,-6.639582633972168,-4.742516994476318,-5.363183498382568,-3.8752496242523193 -4870,4870,A280K,-0.020814739,0.04003729,0.070316406,0.017820957,0.075160398,0.118836564,-0.017571261,-0.024058216,0.194957088,0.043708359,0.036366221000000004,0.137425235,0.003207577,0.072859906,-0.037217992000000005,0.05945985,0.090860946,1.238730648,3.03239212,-1.184081187,-0.611637024,-1.896820274,-2.051867912,-1.036351318,-0.323729408,-1.871969105,0.689393378,-5.191134452819824,-5.099112510681152,-3.7220065593719482,-3.837897300720215,-1.679267406463623 -4871,4871,A280M,-0.009311223,0.039352789,-0.020111633,0.053095138,0.037007801,-0.001755541,-0.055072618,0.036450172,0.160396349,0.040981227,0.03772435,0.012478395,-0.052701661,0.064932038,0.041258237999999996,0.10091253300000001,-0.026896931000000002,1.136552211,2.9797088310000004,-6.49145141,-5.281763527,-7.348269585,-6.782271965,-7.379421592999999,-5.66553038,-6.564189695,-4.463718895,-7.031054496765137,-7.435395240783691,-6.865154266357422,-6.550877571105957,-5.5659003257751465 -4872,4872,A280L,-0.019694195,0.025673355,-0.01540002,0.007323596999999999,-0.032356586,-0.057590987,-0.072462931,0.033074541,-0.041337933,0.039685653,0.011661056000000001,0.004835358,-0.035635398,0.002207067,0.012440126000000001,0.006857073000000001,-0.071570244,1.211678106,2.6355949969999997,-4.813150089,-4.032753578,-5.564761322000001,-4.840736778,-5.8643560489999995,-3.763142715,-5.606936851,-1.7401011290000001,-5.666804790496826,-6.586047172546387,-5.577006816864014,-5.53835391998291,-4.675619125366211 -4873,4873,A280N,-0.100248609,-0.018032502,-0.058417893,-0.017596726,0.011650471,0.051055959000000005,-0.14568825800000001,-0.054808959000000004,0.173896735,0.033277352999999996,-0.06934235700000001,-0.008394361999999999,-0.10844142300000001,0.001750831,-0.036944283,0.03792009,-0.014619149,1.010840145,2.6171390469999998,-3.237784247,-3.241913925,-3.439167419,-3.8596982189999998,-3.2476220469999997,-2.400519623,-4.048414061,-2.579443896,-6.821435928344727,-6.22048807144165,-4.54148006439209,-5.733863830566406,-4.616168022155762 -4874,4874,A280Q,0.027686207,0.025232728,-0.048104238,-0.025300793999999998,0.001830592,-0.096644102,-0.016242965,0.071615379,0.015339323,-0.022432942999999997,0.072898398,-0.102096837,0.005888361999999999,-0.037828254,-0.012773333999999999,-0.01482549,0.018486673999999998,1.253057574,2.527943263,-2.338502061,-1.304825294,-2.531812386,-2.752311676,-3.691079041,-1.412481911,-4.0949761360000005,-1.0728794659999998,-4.974845886230469,-4.624611854553223,-3.0790438652038574,-3.65220308303833,-2.3530125617980957 -4875,4875,A280P,-0.052883669,-0.25733373,-1.6387152740000002,-2.026569518,-2.494082504,-0.00500672,-0.053874835,-0.051892502,-0.01778646,-0.024267108,-0.49040035200000004,-1.546081799,-1.7313487490000001,-2.017006479,-2.0361325569999997,-2.489746225,-2.498418782,0.68246934,0.032625318,-6.340728437999999,-5.618385521,-6.792258232000001,-6.4689069439999995,-6.906109055,-5.917982437,-7.183336431,-5.852633053,-10.096820831298828,-9.30841064453125,-7.624163627624512,-8.550121307373047,-8.336386680603027 -4876,4876,A280S,-0.10375860699999999,0.036970363,-0.000966615,0.011164307,-0.015325554,-0.019862738,-0.154398868,-0.053118346,0.024947887999999998,0.058761016,0.015179709,0.022746318999999997,-0.024679548,0.035314076,-0.012985462,0.045050127,-0.075701234,1.067914636,2.733284345,-1.4658669919999998,-1.090643898,-1.631773102,-2.087677582,-1.56996637,-0.94927401,-3.188115681,-0.958801899,-5.370274066925049,-4.458666801452637,-4.387580394744873,-4.799726486206055,-3.970346212387085 -4877,4877,A280R,0.017740767,0.05951084,0.0066375769999999995,0.031565471,0.030679468999999997,-0.035991029,-0.010064205,0.045545737999999995,0.007392147,0.067349827,0.051671853,0.033894026,-0.020618873,0.032269788,0.030861154,0.058416162,0.002942776,1.095273149,2.7862396339999997,-1.0638034729999999,-0.16541465,-2.024160873,-0.934769829,-1.862074379,-0.332597633,-2.244745634,1.42050813,-4.882176399230957,-4.337700366973877,-2.9244544506073,-2.7576980590820312,-1.398998737335205 -4878,4878,A280T,-0.048665015,0.063407862,0.026680456,0.006376666,-0.043402807,-0.05856134599999999,-0.08800637900000001,-0.009323651,0.019177593,0.10099025699999999,0.025825466000000002,0.077937537,-0.024576625,0.036448562000000004,-0.02369523,0.006806875,-0.09361248900000001,1.187963924,2.7009606410000004,-2.185598773,-1.739236038,-3.2333924260000004,-2.007458435,-1.444947906,-2.502959061,-4.939772733,-1.59533492,-5.656887054443359,-5.043535232543945,-4.502134323120117,-4.847465515136719,-4.3910698890686035 -4879,4879,A280W,-0.038685722,0.078896382,0.036756765,0.038898168999999996,-0.06352932900000001,-0.025649927000000003,-0.098913037,0.021541592999999998,-0.005865896,0.114410144,0.04338262,0.057997495,0.015516034,0.088844195,-0.011047857,-0.015685587,-0.11137307099999999,1.320991183,2.6880333519999997,-7.252454016000001,-6.233908027999999,-7.758049736,-7.44266568,-8.285116524,-6.542530113,-6.966581261,-4.720765437,-9.340900421142578,-10.332563400268555,-9.372322082519531,-8.789435386657715,-7.715756416320801 -4880,4880,A280V,-0.057265897999999996,0.043899445999999995,-0.0007795289999999999,0.018186573,0.001853805,-0.037710621,-0.055955917,-0.058575878,0.015356202,0.063123972,0.02467492,0.029402109,-0.030961166000000002,0.029258505,0.007114641,0.01941985,-0.015712241000000002,1.1928235059999999,2.7976534269999997,-4.861397794,-4.380884155,-5.938834618,-4.366484299,-5.466163773,-4.154622123999999,-5.364610357,-3.554281568,-6.439386367797852,-6.307311058044434,-6.201417446136475,-5.7325358390808105,-5.741657733917236 -4881,4881,A280Y,-0.009454823000000001,-0.029276731,0.007612951999999999,0.005662316999999999,-0.060442832,-0.027633511,-0.07552735299999999,0.056617707,0.084827758,-0.030583528,-0.027969934,-0.021769447999999997,0.036995351,0.0066698669999999995,0.004654767,-0.035173565,-0.085712099,1.2318136990000002,2.464042643,-6.434412991,-5.711936287,-6.985424469,-7.251418655,-6.69424234,-5.529043205,-6.376621215,-3.2260692389999996,-8.366969108581543,-8.452112197875977,-7.593432426452637,-7.527932167053223,-6.481106758117676 -4882,4882,S281A,0.01085553,-0.015615371999999999,0.007514437,-0.039074234,0.016871306000000003,0.010089789,-0.002499243,0.024210303,-0.016133236000000002,0.0028123609999999998,-0.034043104,0.023667262999999997,-0.00863839,-0.019060533,-0.059087935,-0.021681544,0.055424155999999995,1.217323422,2.511087281,0.14427984,-0.276025124,0.283797142,0.457348663,-0.21779145100000002,0.474069969,-1.6031158859999999,2.38968392,-2.321037769317627,-2.126124858856201,-1.9033559560775757,-1.204817295074463,-2.075361728668213 -4883,4883,S281C,0.053243195,-0.048376630999999996,0.025057258,-0.001752361,-0.23962318300000002,0.10622102900000001,0.069766883,0.036719507,-0.001240994,0.036123201,-0.132876462,0.096226065,-0.04611155,0.078779399,-0.082284121,-0.09481436800000001,-0.384431997,1.297311562,2.346617768,-5.707864627,-6.809401367,-6.401614891,-4.579835785,-5.777933029,-4.970538063,-5.787106692999999,-2.106891927,-5.4968695640563965,-5.778947830200195,-5.989331245422363,-4.206520080566406,-5.992151260375977 -4884,4884,S281E,-0.007462842,-0.033342317,-0.043318389000000006,-0.023829752000000003,0.019996552,-0.040562389,-0.017109755,0.002184072,0.034342079,0.009265406,-0.075950039,-0.002017359,-0.084619418,-0.039557422,-0.008102082,0.004274437,0.035718666,1.297628574,2.6812648269999997,-2.8093740510000003,-3.967486343,-2.861523804,-2.701222801,-3.0455704189999997,-1.4710668869999999,-3.321301437,0.440367555,-1.7947492599487305,-1.9259734153747559,-3.2634267807006836,-2.7325336933135986,-2.7852892875671387 -4885,4885,S281D,-0.077237476,0.0029675929999999997,0.040606798,-0.042394062,-0.313969132,0.002262854,-0.113210404,-0.041264547,0.014181001,0.031783352,-0.025848166000000002,0.112432165,-0.031218568999999998,0.07422113,-0.15900925400000002,-0.16092539,-0.46701287399999997,1.2851074359999999,2.1269862969999997,-6.070603934,-7.370316093,-6.429463516,-4.561423157,-5.710173973,-6.281642928999999,-5.305890456,-1.6161453609999998,-2.4601409435272217,-3.7580623626708984,-4.686131477355957,-4.315858364105225,-4.36002254486084 -4886,4886,S281G,0.005881285,-0.002000622,0.019861891,-0.010184149,-0.975169465,-0.020873779,-0.003243367,0.015005936999999999,0.012599661000000002,-0.0075252819999999995,0.003524039,0.006250759,0.033473022000000005,-0.008162828,-0.012205468999999998,-0.627710791,-1.322628139,0.903425576,1.460877675,-5.111068877,-5.824794464,-4.640191231,-4.148793312,-5.159087387,-5.782477988999999,-5.097862031,-1.862763575,-4.532079696655273,-4.305606842041016,-4.070294380187988,-4.428752422332764,-4.436531066894531 -4887,4887,S281F,0.005835314,-0.030240181,0.03461422,-0.02603058,-0.310771785,-0.016534306000000002,0.042427538,-0.03075691,-0.11782147300000001,-0.063410001,0.00292964,0.056097074000000004,0.013131366,-0.08209221400000001,0.030031053999999998,-0.228832856,-0.39271071399999996,1.40879113,2.0563085009999997,-6.816553835,-9.1019636,-7.646335411,-4.393347389,-6.8275521470000005,-6.113570625,-4.957149329,-1.6703134080000002,-3.5971155166625977,-3.9042301177978516,-3.004561424255371,-3.5132265090942383,-4.041585922241211 -4888,4888,S281I,0.016365684,-0.036928014,0.08486692800000001,0.013927195,0.005375411,0.039656366,0.04474883,-0.012017463,-0.13261905699999998,-0.03697463,-0.036881397999999996,0.087358428,0.082375427,0.030403221,-0.002548832,0.032532574,-0.021781752,1.104549657,2.74042157,-3.6129030589999998,-5.633551964,-3.5986490630000003,-1.71165712,-3.376043503,-3.744613647,-3.20696145,1.8718924890000002,-2.819288730621338,-4.014845848083496,-2.124138355255127,-1.0943279266357422,-1.9735805988311768 -4889,4889,S281H,0.054028882,-0.018238115,-0.004022538,-0.025059518,-0.0019367639999999999,-0.03088645,0.103399745,0.004658019,-0.017932383,0.005001527,-0.041477756,-0.015201859,0.007156783000000001,-0.024961696000000002,-0.025157339,-0.02463699,0.020763462,1.117285712,2.33927119,-5.241298933,-7.120121147000001,-6.220229385,-3.795232613,-5.0710452880000005,-3.9998662339999997,-4.513869297,-0.754445797,-4.218976020812988,-4.081090927124023,-4.32575798034668,-4.048174858093262,-4.005751609802246 -4890,4890,S281K,0.102200117,0.082772843,0.056158442999999995,0.010449293,0.039123014,0.05533324,0.130421793,0.07397844099999999,0.007471789,0.056828697000000004,0.108716988,-0.031791173,0.144108058,0.08435519,-0.063456605,0.07299372400000001,0.005252303000000001,1.073481308,2.84020224,-5.215079967,-6.733151085,-5.168685638,-4.383788292,-4.709787872,-5.079986946,-4.965727952,-0.8076212759999999,-5.527724266052246,-5.2446441650390625,-4.943699359893799,-4.890582084655762,-5.374418258666992 -4891,4891,S281M,0.046340324,0.002224116,0.047706904,-0.0048645929999999995,-0.060161433,-0.128979141,-0.024259905,0.11694055199999999,-0.10454083900000001,-0.093797547,0.098245779,0.015665204,0.079748604,0.03809005,-0.047819235999999994,-0.04566276,-0.07466010599999999,1.334238511,2.487937686,-4.2298728,-4.375156494,-3.083568878,-2.550840004,-4.812668228,-6.327130394,-4.290896452,0.515005333,-3.695080280303955,-3.5987539291381836,-3.388124465942383,-2.310340404510498,-2.7359509468078613 -4892,4892,S281L,0.065905107,-0.011631881,0.0018307310000000002,-0.018031974,-0.086506977,-0.091464956,0.062313445999999995,0.069496768,0.004320266,-0.010883368999999999,-0.012380391999999999,-0.067961653,0.071623115,-0.053169311,0.017105363999999998,-0.13584259099999998,-0.037171362,1.442559124,2.277564226,-3.177297583,-4.062046188,-3.341900551,-1.9652663119999998,-3.205964935,-3.3113099289999997,-2.280737296,2.077289625,-1.9266717433929443,-2.2544002532958984,-1.310512661933899,-0.1648731231689453,-0.974665641784668 -4893,4893,S281N,0.040756012,-0.002860834,0.122798357,0.08466909800000001,0.131987915,-0.107879686,0.068735407,0.012776616000000001,0.030787635,-0.03542713,0.029705462999999998,0.20039794100000002,0.045198772000000005,0.127648467,0.041689727999999995,0.132208125,0.131767704,1.671448915,3.643209181,-6.011227292999999,-7.464455002,-6.939250213999999,-4.728059029,-5.824749344,-5.099622879,-6.295904547999999,-2.379626388,-4.500410556793213,-4.529430389404297,-5.004105567932129,-4.595590591430664,-4.854860305786133 -4894,4894,S281Q,0.055194085,0.005230144,0.042824474,0.036296139,0.020266376000000003,0.06591668099999999,0.059088891,0.051299279,-0.015463793,0.010167368000000001,0.000292919,0.081910575,0.0037383720000000002,0.028228482000000003,0.044363795,-0.018068113,0.058600865,1.2324898229999999,2.596282822,-4.1971632869999995,-5.045309669,-5.003689911,-3.342460945,-4.060533295,-3.5338226169999998,-3.516328582,-0.41965192799999995,-3.3909783363342285,-3.271118640899658,-3.4647111892700195,-3.135807991027832,-2.982999801635742 -4895,4895,S281P,-0.027270932999999997,-0.031339725,0.0074379630000000006,-1.335726389,-2.321086677,-0.026976293999999998,-0.016570323,-0.037971542000000004,-0.016017306000000002,-0.015280152,-0.047399297,-4.95e-05,0.014925426,-0.775924246,-1.8955285309999998,-2.148886691,-2.493286663,1.76810787,1.345903506,-7.948367554,-8.867920776,-8.178661491,-6.755058891,-8.11775206,-7.82244455,-8.34258018,-6.633886492,-6.068789482116699,-5.992930889129639,-6.3133463859558105,-6.329614639282227,-7.02647590637207 -4896,4896,S281R,0.005082779,-0.012305844,0.021350131,-0.020843979,-0.042061968,-0.02472358,-0.007199574,0.017365132,0.000983058,-0.015506032,-0.009105655,0.010623276999999999,0.032076983999999996,-0.022133862999999997,-0.019554095,-0.055785454000000005,-0.028338481000000002,1.271390899,2.402791355,-4.476138364,-5.889950377999999,-5.344072716,-3.27811203,-3.923041885,-3.9455148089999996,-3.07421391,0.0026729659999999997,-5.164411544799805,-4.815595626831055,-4.464775085449219,-4.457340240478516,-4.29514217376709 -4897,4897,S281T,-0.021101201,-0.05234161,-0.058022299000000006,-0.044012017,-0.000301299,-0.017484335,-0.005929792,-0.036272609,-0.014260803,-0.033776093,-0.070907127,-0.015541949,-0.10050264800000001,0.01182373,-0.099847763,-0.025598469,0.024995871,1.138825853,2.478525199,-1.161035834,-1.7132705380000002,-0.942879318,-0.583026443,-1.587745583,-0.978257286,-2.120028994,0.912376145,-3.0713658332824707,-2.9553825855255127,-2.572265148162842,-2.315603256225586,-2.457782745361328 -4898,4898,S281W,0.066108475,-0.01622506,-0.000134965,-0.018015178,-1.05525514,-0.003238927,0.08065017599999999,0.051566772999999996,-0.030642187999999997,-0.05579145,0.02334133,-0.005308618,0.0050386879999999995,-0.054012977999999996,0.017982623,-0.818980568,-1.291529712,0.660661684,1.371834235,-6.8745367889999995,-8.565600319,-8.089257378,-4.244333984,-6.6388420560000005,-6.834650207999999,-4.720291604,-1.64615239,-3.7939963340759277,-3.876155376434326,-3.8608460426330566,-4.803921222686768,-5.322709083557129 -4899,4899,S281V,0.047241332000000004,-0.021570434,0.001705484,-0.03619773,0.013298684,0.001875731,0.06246056,0.032022102999999996,0.03893919,-0.037257282,-0.005883585,0.002465779,0.0009451889999999999,-0.024586528,-0.047808932,-0.02855442,0.055151787,1.40029765,2.593260959,-2.687188548,-3.0765270539999996,-3.282566368,-1.5275307390000001,-2.800834068,-2.748484512,-2.253096128,1.501451567,-3.2756128311157227,-3.7412309646606445,-1.902992844581604,-1.6112737655639648,-2.1800951957702637 -4900,4900,S281Y,0.03572399,-0.005337117,0.09599159800000001,0.07998810599999999,-0.098156934,0.067030042,0.012192796,0.059255184,0.049781676,-0.050046039,0.039371805,0.084652535,0.10733066,0.127903709,0.032072502,-0.095550959,-0.10076290800000001,1.298172133,2.38351553,-6.813423964,-9.667953979,-7.931272835,-4.094969162,-6.561759338,-5.811164505,-4.944999656999999,-0.782206306,-4.310025215148926,-3.5684099197387695,-3.655508041381836,-4.169853210449219,-4.324974060058594 -4901,4901,L282A,-0.0063642230000000004,-0.014422667,0.038811576,0.040555562999999996,-0.10300104199999999,-0.05789565,-0.015008345,0.0022798989999999997,0.008801646,0.0060313,-0.034876633,0.028267529,0.049355623,0.021281102000000003,0.059830022999999996,-0.094163324,-0.11183876,1.228007054,2.330854478,-6.959006015,-6.847854607,-6.365532257000001,-6.585756821,-9.919909431,-5.075976959,-1.7367670130000001,0.47515616299999996,-4.436785697937012,-5.086832046508789,-4.360256195068359,-4.795934200286865,-5.231263160705566 -4902,4902,L282C,0.024221858,-0.025837514,0.029999442999999997,0.027600952999999998,-0.617685383,-0.048342535,0.06768610900000001,-0.019242394,-0.024250696000000002,-0.08587971900000001,0.034204691,0.020650011,0.039348874,-0.026634519,0.081836424,-0.301801852,-0.9335689140000001,1.5911561840000001,2.123610937,-9.350562146,-8.254893822,-8.907105377,-9.647688782000001,-11.06213683,-8.880985916,-5.606901799,-3.00582367,-8.017884254455566,-8.576838493347168,-8.627054214477539,-7.7287139892578125,-9.631044387817383 -4903,4903,L282E,-0.08928960400000001,-0.028858181,-0.006049179,-1.2107413759999999,-2.95431837,0.023525259,-0.053888225,-0.124690983,-0.033275574,-0.020251298,-0.037465064,0.031192466000000002,-0.043290823,-0.909849571,-1.5116331809999999,-2.7834426110000003,-3.1251941289999996,0.5104398720000001,0.734900087,-13.18431576,-13.10236191,-11.90380754,-13.29089147,-15.03427296,-12.59024492,-8.428003155,-8.955041227,-9.948681831359863,-11.581175804138184,-12.047969818115234,-10.878409385681152,-11.5902738571167 -4904,4904,L282D,0.095681055,-0.490128511,-1.612933182,-1.888378306,-2.529507892,-0.029363657999999997,0.12046699599999999,0.07089511400000001,-0.010494479,-0.210853365,-0.769403657,-1.643502025,-1.582364339,-1.971275849,-1.805480762,-2.438328709,-2.620687074,1.314422415,0.065799607,-13.63465051,-13.40165312,-12.88160228,-13.744752300000002,-14.71708669,-13.42815817,-8.428003155,-8.955041222,-12.044588088989258,-12.63670825958252,-14.237994194030762,-12.806255340576172,-13.648030281066895 -4905,4905,L282G,-0.008902769,-0.006361363,0.046912974,-1.146896856,-2.415650406,-0.023271938,0.028700842,-0.046506379,-0.027799141,-0.010859151000000001,-0.001863574,0.014371325,0.079454622,-0.6814828479999999,-1.6123108640000001,-2.106418595,-2.7248822169999998,1.699155243,1.344656418,-13.19512981,-12.99191829,-12.10270261,-13.56666977,-15.39203446,-11.92232394,-7.1713415220000005,-5.954071214,-7.873059272766113,-9.139350891113281,-8.823809623718262,-9.269796371459961,-10.14126968383789 -4906,4906,L282F,-0.055590161,0.0059819109999999995,0.057414232,0.004002467,-0.663794413,-0.13047984099999999,-0.054541186,-0.056639135,-0.018528412,0.01289498,-0.000931159,0.013658647,0.101169817,-0.092011034,0.10001596800000001,-0.404161934,-0.923426892,1.5756861519999998,1.971424326,-6.763994745,-6.537991333,-5.160462135,-7.389497696,-8.251776886,-6.480245674,-4.911864498,-3.1136379339999998,-6.056268692016602,-6.149664878845215,-6.019725799560547,-6.380126953125,-7.056898593902588 -4907,4907,L282I,-0.030712997000000002,-0.08560336800000001,0.073240526,0.014857091999999999,0.07867216,0.036917857000000005,-0.030478515,-0.030947479,0.024621081,-0.101026579,-0.070180156,0.058977284000000005,0.08750376800000001,-0.041905127,0.07161931,0.021191795,0.136152524,1.173520855,2.612980945,-0.985986638,-0.738607407,-1.457445915,-1.5558619230000001,-1.333970917,0.155952972,-1.698817496,0.121882705,-3.883673667907715,-3.650618553161621,-3.600116729736328,-3.3101882934570312,-3.358412742614746 -4908,4908,L282H,-0.079556787,-0.06868542799999999,-0.665358415,-1.952067363,-3.0112685480000003,-0.00296692,-0.048420415999999994,-0.11069315800000001,-0.029361256000000002,-0.054606175,-0.08276468,-0.34075544799999996,-0.9899613820000001,-1.782472624,-2.1216621019999997,-2.8515854760000003,-3.1709516189999998,1.501122905,0.762066714,-13.62198905,-12.73985181,-12.24635916,-15.09889507,-14.53711644,-13.48772279,-8.428003155,-8.955041222,-10.863544464111328,-11.026805877685547,-10.86954116821289,-12.482518196105957,-12.615657806396484 -4909,4909,L282K,-0.12679685699999999,0.004379624,-0.8014637990000001,-2.0804190940000002,-2.571033681,0.049597325,-0.080987092,-0.17260662100000002,0.049259315,0.04326869,-0.034509442,-0.383430637,-1.21949696,-2.225309282,-1.935528905,-2.391332146,-2.7507352160000003,1.474676645,0.655737633,-12.59331108,-12.7056953,-11.95226952,-12.99592255,-12.95067691,-12.36199111,-8.428003155,-8.955041235,-13.488618850708008,-12.599553108215332,-13.438697814941406,-12.703374862670898,-13.205421447753906 -4910,4910,L282M,-0.011839937,-0.016202038000000002,0.129120078,0.050533957000000004,0.01266562,-0.032253916,-0.011335874,-0.012343999999999999,-0.00109089,-0.006299305,-0.026104771000000002,0.138454299,0.119785856,0.025305865,0.075762048,-0.01373452,0.03906576,1.257108315,2.684097378,-1.763789801,-2.429444473,-2.68372496,-1.717015556,-1.619271225,-0.36949279,-2.542521292,-2.3171212430000003,-5.627723217010498,-5.819367408752441,-5.762407302856445,-5.243743896484375,-5.289525032043457 -4911,4911,L282N,-0.078977727,-0.04154513,0.019547974,-1.903827248,-2.321377818,0.032683298,-0.007880062,-0.150075392,-0.086719893,-0.021768745,-0.061321515,0.014509371,0.024586576000000002,-1.4593924880000002,-2.3482620069999998,-2.023355361,-2.619400274,1.09625668,0.750717847,-13.16298647,-13.08984703,-11.10187752,-14.15800237,-13.84783105,-13.61737439,-8.428003155,-8.955041242,-10.775195121765137,-11.028432846069336,-11.781343460083008,-12.319181442260742,-12.983505249023438 -4912,4912,L282Q,-0.084061408,-0.02514229,0.03698005,-0.013831643000000001,-1.7222842090000001,-0.03406479,-0.069408463,-0.09871435199999999,-0.044841389,0.007363813,-0.057648393,0.054368744000000004,0.019591356,0.031708728,-0.059372013,-1.6238038680000002,-1.82076455,0.624152881,1.311173159,-11.75916212,-12.45222457,-11.13783887,-11.96074274,-11.8455355,-11.3994689,-8.048662405,-7.247377752999999,-10.239246368408203,-11.206012725830078,-10.38840389251709,-11.137813568115234,-11.845149993896484 -4913,4913,L282P,-0.041060384,-0.8257473809999999,-1.903780429,-2.180446576,-2.427915802,-0.010656915,-0.009637888,-0.07248288,0.041194232000000004,-0.600903414,-1.050591348,-2.028956322,-1.778604536,-2.228943566,-2.131949585,-2.263687516,-2.592144088,1.368162314,-0.144691753,-13.08374705,-13.0562671,-12.13835667,-13.41531433,-14.69991937,-12.10887778,-8.422041587999999,-8.92849771,-11.473393440246582,-10.156970977783203,-11.650850296020508,-13.307035446166992,-11.987241744995117 -4914,4914,L282S,-0.011399953,-0.030331722000000002,0.066856979,0.016709488999999998,-1.65506219,-0.037299618,0.020116828,-0.042916733,-0.04014848,-0.013204324,-0.047459119,0.047250607,0.086463351,0.066552627,-0.03313365,-1.4731924330000001,-1.836931946,0.581981385,1.315810913,-11.03507537,-10.89045743,-8.511405144,-11.98425767,-12.29861272,-11.49064389,-5.557301726,-3.356527474,-7.092334747314453,-7.855807781219482,-7.646515846252441,-8.71496295928955,-8.799148559570312 -4915,4915,L282R,-0.052282905,-0.503940882,-1.761141165,-2.017129684,-2.703589801,0.001120214,-0.029214307000000002,-0.075351503,-0.014434746000000002,-0.23265408899999998,-0.775227674,-1.825003591,-1.6972787390000001,-2.022443646,-2.011815721,-2.415710292,-2.99146931,1.109877607,-0.02789721,-12.78764478,-12.97090181,-12.07993506,-12.88355535,-13.55982487,-12.44400683,-8.428003155,-8.955041242,-12.601086616516113,-11.170442581176758,-12.252047538757324,-12.504382133483887,-12.55695915222168 -4916,4916,L282T,-0.03096509,-0.027274398,-0.012731963999999998,0.024637596,-0.231657908,0.039189424,-0.005562998,-0.056367180999999995,0.030266843999999998,-0.05366835599999999,-0.00088044,-0.040834917000000005,0.015370989,-0.016680716,0.06595590700000001,-0.273546517,-0.18976929899999997,1.4582148209999999,2.0556633619999998,-7.676662445,-7.786269516,-5.872508904,-8.73371151,-9.227489861,-6.763332436000001,-4.402049908,-1.406968372,-6.053945064544678,-6.636934280395508,-5.877590179443359,-6.726929664611816,-6.637872695922852 -4917,4917,L282W,-0.059803572,-0.096267983,-1.344352846,-1.780907616,-2.781623897,-0.023238422999999998,-0.036687557,-0.08291958599999999,-0.049234397,-0.036756795,-0.155779171,-0.887070025,-1.801635666,-1.955206538,-1.6066086940000002,-2.723289393,-2.8399584,2.0975165319999998,0.875908585,-11.63428513,-11.64499702,-10.64677985,-11.54240542,-12.60990466,-11.72733871,-8.428003155,-8.955041236,-8.833017349243164,-9.218949317932129,-9.176188468933105,-9.979360580444336,-10.665809631347656 -4918,4918,L282V,-0.033539782000000004,-0.060183293,0.040918414,-0.014758485,-0.020573364,-0.00988052,-0.009174917,-0.057904647000000004,-0.017338213999999998,-0.036731061,-0.083635525,0.03151187,0.050324957999999996,-0.038682434,0.009165464,-0.014466388,-0.026680338999999997,1.265485044,2.416220875,-2.486444519,-2.276941559,-1.784178917,-2.882027328,-4.020611403999999,-1.468463387,-1.672163679,0.8643638709999999,-3.9647247791290283,-2.6495871543884277,-3.0097317695617676,-3.2595224380493164,-3.000582695007324 -4919,4919,L282Y,-0.09826043300000001,-0.082840786,-0.33279512699999997,-1.633467035,-2.60798928,-0.079502726,-0.082745814,-0.113775051,-0.102314702,-0.086097144,-0.079584428,-0.086591695,-0.578998558,-1.58069694,-1.686237129,-2.445689808,-2.770288752,0.926737575,0.714213165,-12.12871137,-11.5340106,-11.29373071,-12.56489552,-12.89013869,-12.36078133,-8.428003155,-8.95504123,-8.458913803100586,-8.990692138671875,-8.62379264831543,-9.529995918273926,-10.215429306030273 -4920,4920,I283A,0.031470879,0.049791319,0.037768479,0.06238399,-0.537631351,-0.000624303,0.038498753,0.024443003999999997,0.032871686000000004,-0.09715811,0.196740747,0.018623557,0.0569134,0.031880449,0.09288753,-0.442120767,-0.633141934,0.633006162,1.441665311,-4.14370215,-6.564234894,-3.092006439,-1.638683884,-4.629826355,-4.793759178,-3.338428683,1.183837691,-1.7548558712005615,-2.3295483589172363,-2.3757944107055664,-2.768582820892334,-3.8006529808044434 -4921,4921,I283C,0.121179051,0.107003363,0.086868051,0.14231138599999998,-0.657012279,-0.027048822,0.154521438,0.08783666400000001,0.047843912999999995,-0.05257339,0.26658011600000003,0.045003413,0.128732688,0.088204515,0.19641825699999999,-0.48642750700000004,-0.8275970509999999,0.614914715,1.421654264,-8.167929884,-10.48410428,-8.024063385,-6.232017302999999,-8.061752335,-8.03771212,-5.196253727,-2.259998438,-6.8551435470581055,-7.224873065948486,-6.997132301330566,-6.805456638336182,-8.937078475952148 -4922,4922,I283E,0.051217483,0.076399452,0.03256536,-1.0353718509999998,-2.601698129,-0.00037549999999999997,0.10060563300000001,0.0018293329999999998,-0.031887886000000004,-0.063245147,0.21604405100000001,0.016283475,0.048847244000000005,-0.538031649,-1.532712052,-2.725471013,-2.477925245,0.771546738,0.8453728770000001,-12.03870164,-14.19002785,-10.02544182,-10.71721786,-12.17702981,-13.08379086,-9.066486241,-7.600373241000001,-6.042776107788086,-5.739679336547852,-5.154442310333252,-6.4645538330078125,-7.032660007476807 -4923,4923,I283D,0.075010206,-0.255157678,-1.67594081,-1.915902265,-2.7888574889999997,-0.064807294,0.127006231,0.023014181,-0.007570611,-0.15132878800000002,-0.35898656700000003,-1.167550513,-2.184331106,-1.975068838,-1.8567356919999998,-2.637463395,-2.9402515830000002,2.479119878,1.040888058,-12.98328707,-15.05801871,-11.7931121,-11.7786171,-13.04835824,-13.23832921,-9.066486241,-7.600373241000001,-7.66925048828125,-6.722441673278809,-6.3516974449157715,-7.1355977058410645,-8.660969734191895 -4924,4924,I283G,0.00841945,0.06324863900000001,0.050212600999999996,-1.074840201,-2.247811139,-0.027790242000000003,0.046688957,-0.029850058,0.012110808999999998,-0.073147911,0.199645188,0.041749982000000005,0.058675219,-0.553903814,-1.5957765869999998,-2.397469156,-2.098153122,1.5413125,1.263939184,-10.32637661,-12.43875707,-9.753404114,-8.528417503,-10.35202051,-10.55928384,-6.705257962,-4.368903826,-5.160435676574707,-5.707740783691406,-4.522996425628662,-5.2039594650268555,-6.519784450531006 -4925,4925,I283F,-0.0587183,0.022810063,0.057892668,0.068766402,-0.123745791,0.03113466,0.010064407,-0.127501007,0.015709742,-0.113849663,0.159469788,0.11898656,-0.0032012240000000003,0.17761143399999998,-0.040078631,-0.12486108800000001,-0.122630494,1.226098114,2.254828956,-2.263350375,-2.091758324,-3.897251312,-2.3589753190000002,-2.041904213,-0.926862709,-2.5237125330000003,0.42777754100000004,-4.43231201171875,-5.863693714141846,-5.2371745109558105,-5.540287494659424,-5.4076080322265625 -4926,4926,I283H,0.0030751159999999997,0.08844879300000001,0.080689247,0.086491254,-2.078123175,0.018155201,-0.010737295,0.016887527,-0.009880693000000001,-0.040085156000000004,0.216982741,0.059959962,0.10141853199999999,0.084568454,0.088414054,-1.74239138,-2.413854969,0.593308359,1.306097648,-11.03807585,-15.91757889,-9.080909927,-8.474869437999999,-10.66354205,-11.05347896,-6.16566191,-1.454240165,-5.628582000732422,-6.9024977684021,-4.886640548706055,-7.157500267028809,-7.830847263336182 -4927,4927,I283K,-0.033363263,0.090361426,0.033530172000000004,-0.31869160399999996,-2.2499305769999998,0.005545774,0.022117593999999997,-0.088844119,0.026230291,-0.033819149,0.214542,0.114736719,-0.047676375,0.05473879,-0.692121998,-1.846537857,-2.653323296,0.709068722,1.304894298,-12.36120688,-14.21554958,-10.1972829,-10.70731776,-12.19367207,-14.49221211,-9.066486241,-7.600373241000001,-6.435085296630859,-6.711524963378906,-5.261836528778076,-6.290868759155273,-6.942713737487793 -4928,4928,I283M,0.045112032999999996,0.09082645,0.073791025,0.064655477,-0.088552239,-0.081727853,0.081430124,0.008793941999999999,0.000315415,-0.030034094,0.211686994,0.064098947,0.083483103,0.013542573,0.11576838099999999,-0.157879617,-0.01922486,1.070833104,1.919357515,-4.004889311,-4.008004608,-4.000053047,-4.4612294310000005,-3.788598557,-3.766560913,-4.2179196139999995,-1.342122456,-4.185498237609863,-4.5675435066223145,-4.950153350830078,-4.85473108291626,-4.546307563781738 -4929,4929,I283L,0.059370475,0.055494218,0.060994300999999994,0.06392191400000001,-0.190349095,-0.051707737999999996,0.06646817299999999,0.05227277599999999,0.010576258,-0.118033435,0.22902187,0.027483837999999997,0.094504763,0.012760958999999999,0.115082869,-0.23469552899999999,-0.146002661,1.556426246,2.224228215,-4.005741454,-4.802651421,-4.2861185,-3.877147926,-3.141469505,-3.9213199160000003,-3.7095007439999996,-0.067305242,-3.629871368408203,-3.7763442993164062,-3.6736788749694824,-3.4327900409698486,-3.5883607864379883 -4930,4930,I283N,-0.030648929,-0.029058431000000003,-0.09197065,-1.530969957,-2.485288831,0.034436635,0.011603071000000001,-0.072900928,-0.013120868,-0.23348127300000002,0.17536441100000003,-0.00994266,-0.17399864,-1.090462256,-1.9714776580000002,-2.354916805,-2.615660856,2.013138297,1.306079846,-11.9200045,-14.64477127,-11.35741799,-10.06872898,-11.85558034,-11.6735239,-8.13912334,-5.026295703,-6.020562171936035,-6.559982776641846,-5.2658843994140625,-6.336705684661865,-8.033303260803223 -4931,4931,I283Q,0.018505338,-0.019192578999999998,0.04345886,0.033764477,-1.9552176419999998,-0.073513621,0.026432422999999997,0.010578253000000001,0.012311433,-0.17561775899999998,0.137232601,-0.030118162999999996,0.11703588300000001,0.011300258999999998,0.056228695,-2.049034307,-1.8614009759999999,1.015707149,1.30464146,-12.30227622,-13.61869175,-10.62490625,-11.61660606,-12.22255326,-13.42862379,-8.414966215,-5.823655372,-5.151904106140137,-5.639397144317627,-4.3932390213012695,-6.164228439331055,-6.463343620300293 -4932,4932,I283P,0.031016147,0.056008005,-0.731239346,-1.76919245,-2.6138816080000002,-0.025240967000000003,0.067333854,-0.005301561,0.039669411,-0.08784305,0.19985906,-0.337616518,-1.124862174,-1.7063336130000002,-1.8320512869999999,-2.5026217490000002,-2.725141466,1.5058702919999998,0.78508746,-12.14147141,-14.02287171,-11.11407906,-10.76376951,-12.20034685,-12.6062899,-9.066486241,-7.600373241000001,-7.132990837097168,-7.719173908233643,-7.123619079589844,-6.795289039611816,-9.162368774414062 -4933,4933,I283S,0.070348948,0.105294123,0.10049716300000001,0.10085286800000001,-1.487969518,-0.026790522999999997,0.09957900300000001,0.041118893,-0.007444504,-0.030907016000000002,0.241495262,0.087790165,0.113204161,0.101033506,0.10067223,-1.2603310559999998,-1.71560798,0.667836286,1.3329351390000002,-7.259293163,-9.757903069,-7.19049762,-5.658660697999999,-7.298424904,-6.3909795229999995,-5.004686594,-2.261343798,-4.1290388107299805,-4.582278728485107,-3.973572254180908,-4.549367427825928,-5.893740653991699 -4934,4934,I283R,0.025069288,0.075470984,0.066976878,0.071882627,-1.9482486419999998,-0.002438317,0.052025095,-0.001886519,0.027048027000000002,-0.068010175,0.218952142,0.047321063,0.086632692,0.11972595300000001,0.024039301000000003,-1.69943643,-2.197060853,0.569567267,1.30601774,-12.39829141,-12.80030426,-10.64962248,-11.28397385,-12.31113908,-14.94641736,-6.271800121,-1.858296571,-5.726864814758301,-6.249262809753418,-5.135280609130859,-5.846032619476318,-7.314810276031494 -4935,4935,I283T,0.053066206,0.06822291400000001,0.040272361,0.035321798,-0.30099536600000004,0.015663807,0.09802277400000001,0.008109638,0.034167308,-0.081143822,0.217589649,0.050691167999999995,0.029853553999999997,0.039052861,0.031590734,-0.311787741,-0.29020299,0.733911523,1.5394749269999999,-6.568960875,-7.684437492000001,-5.048252525,-5.292153702,-7.796407509,-7.023553146,-4.56979412,-1.1242438,-3.997016191482544,-4.442614555358887,-3.9376559257507324,-4.39658260345459,-5.262237548828125 -4936,4936,I283W,0.01963929,0.035328206,0.030233693,0.059807255999999996,-1.71314797,-0.00078643,0.03358698,0.005691600000000001,-0.0030160559999999996,-0.095860123,0.166516535,0.029254767,0.031212617999999998,0.049099363,0.070515148,-1.186929665,-2.239366275,0.585629736,1.330068682,-9.626558827,-9.749376372999999,-10.88805367,-7.947074173,-8.848055344,-10.70023458,-5.3981691860000005,0.54274985,-6.204946517944336,-7.105166912078857,-6.257321357727051,-7.279338836669922,-7.648070812225342 -4937,4937,I283V,0.071986976,0.068715027,0.084233081,0.056110357,-0.030749035,0.020343736,0.08410707699999999,0.059866874,0.014520176999999999,-0.058106625999999995,0.195536679,0.05498419400000001,0.113481968,0.062635996,0.049584718,-0.132006118,0.070508048,1.382819574,2.332674662,-1.719222194,-1.4818294980000002,-1.489164352,-1.661772316,-2.323498833,-1.63984597,-2.017680151,1.307049636,-2.445585012435913,-1.7215951681137085,-2.5494132041931152,-2.694962501525879,-3.2700469493865967 -4938,4938,I283Y,-0.019137919,0.023169872,0.023007478999999997,0.067292346,-0.082166485,0.031967846,-0.058736069,0.020460232,0.158117888,-0.10256865300000001,0.148908397,0.035997653,0.010017305,0.08562900300000001,0.048955688,-0.063127466,-0.101205504,1.313105599,2.474889621,-6.397742931,-8.882764267,-7.280711273,-6.313466461,-4.687724472,-4.82404818,-4.951559262,1.652259243,-4.865457534790039,-6.373970031738281,-5.442849636077881,-6.751211166381836,-6.334842681884766 -4939,4939,K284A,-0.0011670930000000001,-0.019496299999999998,0.011285005,0.006379218000000001,-0.038962118999999996,0.052943048,-0.032402192,0.030068006,-0.014523295,-0.032338695,-0.006653905,0.035927039,-0.013357029,0.004329126,0.008429309,-0.018958354,-0.058965884,1.671448915,3.643209181,,,,,,,,,-2.9373958110809326,-2.860499382019043,-3.192408800125122,-2.9744391441345215,-3.8150720596313477 -4940,4940,K284C,-0.030232923999999998,-0.007676652,-0.000796423,-0.032056912,-0.9186700179999999,0.053184482000000005,-0.026563657999999997,-0.03390219,0.026977848999999998,-0.009735615999999999,-0.005617687,0.024915488,-0.026508333999999998,-0.043491694000000004,-0.02062213,-0.554367288,-1.282972748,1.184962493,1.613005555,,,,,,,,,-7.887598514556885,-8.35586929321289,-9.021193504333496,-8.678150177001953,-10.577017784118652 -4941,4941,K284E,-0.003045591,0.003268006,-0.013789500000000001,0.007263861999999999,-0.027480766,0.051614350999999996,-0.036752754,0.030661572,0.006596286,-0.025887765,0.032423777,-0.00867321,-0.018905789,0.035238213,-0.020710489,-0.035196934,-0.019764597,1.3568317490000001,2.646566522,,,,,,,,,-2.5973892211914062,-3.2449686527252197,-3.6388375759124756,-3.5728092193603516,-4.418100833892822 -4942,4942,K284D,0.001921604,-0.019355702,-0.009024555,0.023140319,-0.061476142000000004,0.027800756,-0.046579672999999995,0.050422880999999996,0.003573463,-0.001629866,-0.037081538,0.0055154159999999995,-0.023564526000000002,-0.0024013420000000003,0.04868198,-0.035446201000000004,-0.087506082,1.216961722,2.512366998,,,,,,,,,-3.164613723754883,-4.284966945648193,-4.090908050537109,-4.372202396392822,-5.518776893615723 -4943,4943,K284G,0.009761721,-0.009492509,-0.0051139390000000005,-0.008522142,-0.092461612,0.032471881,-0.025707155,0.045230596,-0.008624438,-0.033617729,0.014632711999999999,0.014509484,-0.024737361,0.005783811999999999,-0.022828096000000003,-0.071991424,-0.1129318,1.196506357,2.253408402,,,,,,,,,-4.398432731628418,-4.382718086242676,-4.413438320159912,-4.3710832595825195,-5.100457668304443 -4944,4944,K284F,-0.065972166,-0.034221412,-0.01915904,-0.11758794300000001,-0.286851229,-0.008126857,-0.081020365,-0.050923965999999994,0.015936925,-0.027179296000000002,-0.041263528,-0.021817568,-0.016500511000000002,-0.05743259,-0.17774329600000002,-0.204696938,-0.369005519,1.460655214,2.126313878,,,,,,,,,-8.212443351745605,-8.383024215698242,-8.39149284362793,-8.93769645690918,-10.378488540649414 -4945,4945,K284I,-0.047915060999999995,-0.004677264,0.008121187,0.007687492,-0.514835422,0.032596239,-0.056873817,-0.038956305,-0.056263645999999994,0.089189688,-0.09854421599999999,0.114206104,-0.097963731,0.069152347,-0.053777364,-0.217600885,-0.812069959,1.017217977,1.8426262409999998,,,,,,,,,-7.4652557373046875,-7.280307769775391,-7.570296287536621,-7.948925495147705,-8.5648832321167 -4946,4946,K284H,-0.027958999,0.013219203,0.042184872000000005,0.01037147,-0.005217661,0.028335074,-0.058262130999999995,0.002344133,-0.026491815,-0.01062156,0.037059966,0.079750958,0.004618786,0.025085209,-0.004342269,0.016745608999999998,-0.02718093,1.200113388,2.611282903,,,,,,,,,-4.935063362121582,-5.204450607299805,-5.543143272399902,-5.504143714904785,-6.1717376708984375 -4947,4947,K284M,0.039465525,-0.018350618,-0.032598517,-0.052190732000000004,-0.107795746,-0.0037128659999999996,0.004173865,0.074757184,-0.032671043,-0.058862659000000005,0.022161424,-0.045925834000000006,-0.019271199,-0.064225399,-0.040156065,-0.096675394,-0.118916097,1.369948383,2.282464032,,,,,,,,,-6.885523319244385,-7.112917900085449,-7.408744812011719,-7.427133560180664,-8.402616500854492 -4948,4948,K284L,-0.030876035,-0.005206454,0.004979038,0.000922447,-0.044259464000000005,0.051762104,-0.064098921,0.002346851,-0.00201594,0.000140074,-0.010552981000000001,0.012523693,-0.002565618,0.016421316000000002,-0.014576423,-0.051654697,-0.03686423,1.4037943080000002,2.51319102,,,,,,,,,-6.003368377685547,-5.843951225280762,-6.122670650482178,-6.171976089477539,-7.620960235595703 -4949,4949,K284N,-0.005976686,-0.054977825999999994,-0.017956623,-0.063212299,-0.074528787,-0.011069381000000001,-0.032354044,0.020400671999999998,0.007503757,-0.078676345,-0.031279307,-0.024302534,-0.011610711999999999,-0.06775838,-0.058666218,-0.11145271,-0.037604862999999995,1.279133157,2.119113416,,,,,,,,,-3.5802459716796875,-4.185488700866699,-4.171137809753418,-4.324921131134033,-5.007966995239258 -4950,4950,K284Q,0.0032249559999999997,-0.036001727000000004,-0.048279694000000005,-0.0067570830000000005,-0.071555783,0.049682372,-0.037211358,0.043661269,-0.00904615,-0.067012131,-0.004991322,-0.071459227,-0.025100161,-0.053629752,0.040115587,-0.105303744,-0.037807822000000005,1.61037071,2.4644736000000003,,,,,,,,,-3.439997911453247,-3.2696285247802734,-4.1688361167907715,-3.788647413253784,-4.388910293579102 -4951,4951,K284P,-0.039515673,-0.0026040620000000003,-0.199204388,-1.59051964,-2.593265847,0.032548807,-0.051037427,-0.027993918,-0.039058728,-0.015559469,0.010351345999999999,-0.04020411,-0.358204666,-1.312285352,-1.868753928,-2.3761040980000003,-2.8104275960000002,0.959654553,0.748398298,,,,,,,,,-5.032255172729492,-5.118062973022461,-5.334890365600586,-5.1491312980651855,-5.0520830154418945 -4952,4952,K284S,0.019029421,0.010499555,0.0033442059999999997,0.016708824,-0.020231824,0.035576829,-0.018134999,0.056193840999999994,-0.006438312,0.00108266,0.01991645,0.027294527000000002,-0.020606115,0.04676759900000001,-0.013349951,-0.027272464,-0.013191183,1.380401521,2.613084933,,,,,,,,,-3.3343420028686523,-3.3871798515319824,-4.029140949249268,-3.952274799346924,-4.63980770111084 -4953,4953,K284R,0.029148916,0.009022216999999999,0.004103836,0.017886226,-0.041719978,0.019733564,-0.014501422,0.07279925400000001,-0.00243367,0.021426346000000002,-0.003381912,0.041838686,-0.033631014,0.059935774000000004,-0.024163322,-0.019150975,-0.064288981,1.1306588690000001,2.487209058,,,,,,,,,-3.798560619354248,-3.445549488067627,-3.5499234199523926,-3.6959176063537598,-4.40954065322876 -4954,4954,K284T,-0.012975183000000001,-0.023907811,-0.012975258,-0.042232717999999995,-0.090440961,0.029528653,-0.037955704,0.012005338,-0.000845933,-0.03806444,-0.009751181999999999,-0.022809471,-0.0031410440000000004,-0.015327313,-0.069138122,-0.082459895,-0.098422027,1.281367367,2.270237021,,,,,,,,,-4.051001071929932,-3.9648208618164062,-4.878718852996826,-4.616581916809082,-5.240896701812744 -4955,4955,K284W,-0.016195725,0.00863963,0.0036231659999999997,-0.021032951,-0.44988467299999996,0.04982133,-0.062543173,0.030151723,-0.007421921,-0.008298999,0.025578259,0.016236738,-0.008990406999999999,-0.00421365,-0.037852251,-0.31281458300000003,-0.5869547629999999,1.145886887,1.77664944,,,,,,,,,-8.303747177124023,-9.48416805267334,-9.383872032165527,-9.611270904541016,-10.945152282714844 -4956,4956,K284V,-0.027768052999999997,0.0020763820000000003,-0.00975478,0.012846875,-0.26129694800000003,0.014595058999999999,-0.049508061,-0.006028045,0.043468785,0.023254405,-0.019101642,0.017752773,-0.037262332999999995,0.024574407000000003,0.001119342,-0.176720362,-0.34587353299999996,1.42533513,2.198468251,,,,,,,,,-6.566967010498047,-6.1527814865112305,-6.59564208984375,-6.734349250793457,-7.3108930587768555 -4957,4957,K284Y,-0.00451025,-0.011810131000000001,0.023828214,0.011551488,-0.11147226199999999,-0.016285368999999997,-0.030725517,0.021705018,-0.011562315,-0.010912193999999998,-0.012708067,0.032238096,0.015418331,0.008925313,0.014177661999999999,-0.083951464,-0.13899306,1.253507871,2.257540566,,,,,,,,,-7.024633884429932,-7.970948219299316,-8.049089431762695,-8.259397506713867,-9.580390930175781 -4958,4958,H285A,-0.046267157,-0.052390898,0.012269418999999998,-0.04571516900000001,-0.465274388,0.080088467,-0.040147017,-0.05238729599999999,-0.064010873,-0.048071382999999995,-0.056710412,0.002874559,0.021664278999999998,-0.023498758999999998,-0.06793157799999999,-0.306232018,-0.624316758,1.3365430040000001,1.902832985,,,,,,,,,-2.4206478595733643,-1.527543306350708,-1.7152202129364014,-0.43258118629455566,-2.0486645698547363 -4959,4959,H285C,-0.027152107999999998,-0.07850001,-0.082541639,-0.060775824000000006,-0.251095353,0.079985056,-0.027705358,-0.026598858,-0.124907305,0.010243541,-0.16724356099999999,-0.114337169,-0.050746108,-0.025817866000000002,-0.09573378199999999,-0.14693134900000002,-0.355259356,1.550802741,2.320464894,,,,,,,,,-5.692131996154785,-6.036720275878906,-6.535743713378906,-4.143485069274902,-6.498378753662109 -4960,4960,H285E,-0.04668786,-0.077489954,-0.057370818,-0.083205007,-0.33876170899999997,-0.011353925,-0.017635662,-0.075740057,-0.026848862999999997,-0.049955342,-0.105024566,-0.044883499,-0.069858136,-0.056825172,-0.109584841,-0.262738058,-0.41478535899999996,1.200128361,1.874139605,,,,,,,,,-3.278514862060547,-1.277921199798584,-3.786616563796997,-2.323795795440674,-2.740110397338867 -4961,4961,H285D,-0.064282928,-0.082233998,-0.027357107000000002,-0.025369133999999998,-1.535460946,0.121029753,-0.047387509,-0.081178346,-0.098661203,-0.017597391,-0.146870605,-0.008108886,-0.046605327,-0.00703111,-0.043707157999999996,-1.223209889,-1.847712002,0.584649467,1.328290672,,,,,,,,,-3.8927102088928223,-2.079097270965576,-4.200577259063721,-2.721611976623535,-2.899735450744629 -4962,4962,H285G,-0.03437017,-0.034153432000000004,-0.013024638,-0.02675492,-0.50993699,0.090507129,-0.022940508,-0.045799832,-0.067304919,-0.021596973999999998,-0.046709889000000004,0.00076758,-0.026816855,-0.024677812,-0.028832027000000003,-0.280781037,-0.739092942,1.107088895,1.743985783,,,,,,,,,-4.142488479614258,-2.72064471244812,-3.142282009124756,-2.6180152893066406,-2.6850132942199707 -4963,4963,H285F,0.006117895999999999,-0.036883347000000004,-0.024579855,-0.048331434000000006,-0.149276371,0.11128691800000001,0.071738573,-0.059502781,0.024400852999999997,-0.06656580200000001,-0.007200891,-0.05094427,0.00178456,-0.057803082,-0.038859785,-0.08654172199999999,-0.21201102,1.573480749,2.526964858,,,,,,,,,-4.85759162902832,-5.242958068847656,-4.4271745681762695,-4.8969926834106445,-5.356929779052734 -4964,4964,H285I,-0.052110944000000006,-0.108262475,-0.016498274,-1.23904755,-2.723116824,-0.004294424,-0.016216063,-0.08800582400000001,-0.059604628,-0.12248882300000001,-0.094036127,-0.051102167000000004,0.018105619,-0.9004265029999999,-1.577668597,-2.759185255,-2.687048392,1.03424844,0.831650997,,,,,,,,,-4.119388580322266,-3.9967963695526123,-3.264155626296997,-3.1284303665161133,-4.094858169555664 -4965,4965,H285K,-0.029627248999999998,-0.009882353,-0.03269644,-0.050791848,-0.271887231,0.015611008000000001,-0.024860776,-0.034393721,-0.109009218,0.011815511,-0.031580216,0.01232229,-0.07771517,-0.012094987,-0.089488709,-0.165372451,-0.37840201,1.158000938,1.952331174,,,,,,,,,-5.824187755584717,-3.933635950088501,-5.44282341003418,-4.745499610900879,-4.11873197555542 -4966,4966,H285M,-0.081040735,-0.036226921,-0.015397395,-0.065995181,-0.226841047,0.04186132,-0.070107086,-0.091974384,-0.028012836,0.014937559,-0.0873914,0.022134445,-0.052929235,-0.04576579,-0.086224571,-0.10025776300000001,-0.35342433,1.4537318940000001,2.363739969,,,,,,,,,-5.2242655754089355,-4.693675994873047,-4.894627571105957,-4.401677131652832,-5.220096588134766 -4967,4967,H285L,-0.069336279,-0.035497166000000004,-0.02413953,-0.029208635,-0.553995627,0.077208835,-0.043290227,-0.095382331,-0.058612122999999995,-0.020165842,-0.050828489000000004,-0.0013067110000000001,-0.046972349000000004,-0.022405495,-0.036011773999999996,-0.376965626,-0.7310256270000001,1.060233778,1.654608708,,,,,,,,,-3.299457550048828,-3.320272207260132,-2.80576229095459,-2.191263198852539,-3.6188063621520996 -4968,4968,H285N,0.021839973,0.038751369,-0.005295227,-0.04368690099999999,0.024088321,0.06034565,0.027459507,0.016220438,-0.075757703,0.031753077000000005,0.04574966,0.0039702159999999995,-0.014560668999999998,0.012393161000000001,-0.09976696300000001,0.067893098,-0.019716456,1.155290124,2.8654402830000003,,,,,,,,,-3.8593029975891113,-2.636585235595703,-4.081634521484375,-3.1777048110961914,-3.0402259826660156 -4969,4969,H285Q,-0.029835568,0.0033283370000000002,0.057769555,0.013336226000000001,-0.141955412,0.037134086000000004,-0.024020299,-0.035650836,-0.03393331,0.033311942000000004,-0.026655268,0.11306170199999999,0.002477407,0.101224588,-0.074552137,-0.1049178,-0.178993023,1.334330892,2.545821853,,,,,,,,,-3.92202091217041,-2.1138012409210205,-3.790574789047241,-2.791442394256592,-2.6564559936523438 -4970,4970,H285P,-0.079973704,-0.054928174,-0.9141689740000001,-2.113696092,-2.724870193,0.067835534,-0.051419377,-0.108528031,-0.061057115999999995,-0.045898840999999996,-0.063957506,-0.450210971,-1.378126977,-1.901475477,-2.3259167069999998,-2.76323974,-2.6865006460000003,1.6162079719999998,0.7604078009999999,,,,,,,,,-6.215908527374268,-4.0548906326293945,-4.901968479156494,-3.67816162109375,-4.754154682159424 -4971,4971,H285S,-0.042936010999999996,-0.056729840999999996,-0.018897727,-0.019913888,-0.160348785,0.075993374,-0.020595921,-0.065276101,-0.07262481700000001,-0.041467078,-0.071992604,-0.015794267,-0.022001186000000002,0.00694886,-0.046776635999999996,-0.094238832,-0.22645873800000002,1.314890865,2.2801780590000003,,,,,,,,,-3.172020435333252,-1.9918005466461182,-2.959381103515625,-1.8758407831192017,-2.3069353103637695 -4972,4972,H285R,-0.04849393900000001,-0.019034863,-0.017791108,-0.029604352,-0.157191089,0.061143002,-0.037726471,-0.059261405999999996,-0.079473611,0.0037703809999999997,-0.041840107,0.00179255,-0.037374766000000004,-0.014884838000000001,-0.044323865,-0.112055885,-0.202326292,1.4004578840000002,2.288350094,,,,,,,,,-5.645654201507568,-3.817620038986206,-4.848927021026611,-4.359378337860107,-3.873030185699463 -4973,4973,H285T,-0.055620389000000006,-0.043969707999999996,-0.044884067,-0.054940351,-0.113390602,0.063022922,-0.055436848,-0.05580393,-0.090678626,-0.026670265,-0.061269150999999994,0.0039702159999999995,-0.093738349,-0.030304888999999998,-0.079575812,-0.072089658,-0.154691545,1.514346548,2.541142889,,,,,,,,,-3.5655455589294434,-1.958540916442871,-2.960797071456909,-2.1727895736694336,-2.5235891342163086 -4974,4974,H285W,-0.055681479000000006,-0.032883943,-0.014249615,-0.054198737999999996,-0.076231453,0.072687403,-0.062485639,-0.048877317999999996,-0.078175787,0.012021458999999998,-0.07778934400000001,-0.015664917,-0.012834311999999999,-0.020387266,-0.088010209,-0.008240715,-0.144222191,1.30233762,2.631740956,,,,,,,,,-6.027070999145508,-6.119417190551758,-5.949761867523193,-6.832859039306641,-7.366318702697754 -4975,4975,H285V,-0.038604749,-0.021556971,-0.025822966,-0.038819881,-0.8257314490000001,0.084401481,-0.04825374599999999,-0.028955752,-0.02222136,-0.021360147000000003,-0.021753794,0.007942071,-0.059588003,-0.030127387000000002,-0.047512375,-0.483575343,-1.167887555,1.2029670890000002,1.665454901,,,,,,,,,-4.093813896179199,-3.24806809425354,-2.8290367126464844,-2.340603828430176,-3.344003677368164 -4976,4976,H285Y,-0.072056969,-0.041721957999999996,-0.08357903700000001,-0.031318184,-0.09468585300000001,0.050036400999999994,-0.055260606,-0.088853331,-0.023220672999999997,-0.022343827,-0.061100088,-0.08003516299999999,-0.08712291,-0.046817004,-0.015819363,-0.0750808,-0.114290905,1.374097325,2.326613476,,,,,,,,,-4.19928503036499,-4.3691558837890625,-4.1104278564453125,-4.705630302429199,-4.659884452819824 -4977,4977,W286A,-0.03794522,-0.322941308,-1.787981671,-1.9614080230000002,-3.1787981039999997,0.076148022,-0.022854452999999997,-0.053035987,-0.026969418999999998,-0.13907507300000002,-0.506807543,-1.534465091,-2.04149825,-1.9525549119999999,-1.970261134,-3.037843642,-3.3197525660000005,2.656269194,1.056615656,,,,,,,,,-5.2284016609191895,-1.4156293869018555,-2.1303610801696777,-1.2355512380599976,-3.2802276611328125 -4978,4978,W286C,-0.044844145,-0.313323858,-1.7240013459999999,-2.096397703,-2.983761815,0.059320785,0.012885923999999998,-0.102574214,-0.0321029,-0.06455608,-0.562091636,-1.608498837,-1.839503855,-1.880460623,-2.3123347830000003,-2.907757405,-3.0597662239999996,2.757086174,1.145064317,,,,,,,,,-6.736688613891602,-3.7276320457458496,-6.079705238342285,-4.174566268920898,-7.17431640625 -4979,4979,W286E,-0.060069761,-0.034149636000000004,-0.706144653,-1.904946112,-2.545852462,0.044144947000000004,-0.014809628,-0.10532989300000001,-0.069830349,-0.027899284,-0.040399987000000005,-0.321592411,-1.090696895,-1.7934588980000001,-2.016433325,-2.238899075,-2.8528058489999997,1.4850155369999998,0.7610148940000001,,,,,,,,,-6.099212169647217,-2.5940797328948975,-4.109421730041504,-3.2325048446655273,-4.213315963745117 -4980,4980,W286D,-0.098225732,-0.092319389,-0.991545637,-2.162412268,-2.859106006,0.027078649,-0.048379415999999995,-0.148072048,-0.017223036,-0.096065304,-0.088573474,-0.476826718,-1.5062645559999999,-1.9918265519999998,-2.332997984,-2.47505529,-3.2431567219999997,1.632738385,0.734380347,,,,,,,,,-6.281332015991211,-2.6636574268341064,-4.485845565795898,-3.5250258445739746,-4.306002616882324 -4981,4981,W286G,-0.020285201,-0.023080383,-1.0494353159999998,-2.035040286,-3.228429174,0.060527429,0.011754573999999999,-0.052324975999999995,-0.042765965999999996,-0.046775209000000005,0.000614444,-0.654189172,-1.4446814590000001,-1.879770376,-2.190310196,-2.474149566,-3.982708782,1.933994225,0.8605398390000001,,,,,,,,,-6.156779766082764,-1.7352213859558105,-2.3003532886505127,-1.9455586671829224,-3.4259982109069824 -4982,4982,W286F,-0.039678789,0.022006698999999998,-0.05139122,-0.035329727000000005,-0.780425279,0.029596279,-0.008837059,-0.070520519,-0.045872715999999994,0.023657577000000003,0.02035582,-0.049465695999999997,-0.053316743,-0.028385327999999998,-0.042274125,-0.414184251,-1.146666306,1.155829645,1.677639804,,,,,,,,,-3.3433330059051514,-1.407322645187378,-1.2129325866699219,-1.39910089969635,-3.3060522079467773 -4983,4983,W286I,-0.079611889,-0.002497151,-0.001055027,-1.204237153,-2.429502334,0.060793225,-0.03499656,-0.12422721699999999,-0.042629379,-0.045114732000000005,0.04012043,-0.007004702,0.004894649,-0.63365367,-1.774820635,-2.0771152809999998,-2.781889386,1.699155243,1.344656418,,,,,,,,,-4.107790946960449,-1.6605212688446045,-2.297354221343994,-2.1275343894958496,-3.6416447162628174 -4984,4984,W286H,-0.123809877,-0.05872987599999999,-0.039697843999999996,-0.9666943590000001,-1.782739799,-0.008238344,-0.106133802,-0.141485951,-0.04853213,-0.009241173,-0.10821857800000001,-0.016999718,-0.062395969,-0.40166578399999997,-1.531722934,-1.8769255919999999,-1.688554006,1.566215457,1.38598284,,,,,,,,,-5.867130279541016,-3.157223701477051,-3.053417205810547,-4.069023132324219,-4.7482194900512695 -4985,4985,W286K,-0.024663504,-0.036908803999999996,-0.8407895879999999,-1.817969863,-2.566351628,0.00249217,0.038081734,-0.087408741,-0.110334137,-0.11976654800000001,0.04594894,-0.505116357,-1.176462818,-1.891021495,-1.74491823,-2.918318277,-2.214384979,1.742588391,0.792661469,,,,,,,,,-6.664487838745117,-3.356548309326172,-3.904266834259033,-3.7478628158569336,-4.734120845794678 -4986,4986,W286M,-0.070083197,-0.026072183,-0.049894945999999996,0.010723905,-1.6997812630000002,-0.042759615,-0.036310236,-0.10385615699999999,-0.032656403,0.011282621000000001,-0.063426987,-0.01722688,-0.08256301099999999,0.056412628,-0.034964819,-1.576971635,-1.82259089,0.6128761979999999,1.312323321,,,,,,,,,-4.773690700531006,-2.767399311065674,-3.0403683185577393,-2.0886940956115723,-4.086877822875977 -4987,4987,W286L,-0.056208465,-0.026258346000000002,-0.043624029,-1.299020745,-2.244688275,0.015539315,-0.022969213,-0.089447716,-0.027575447000000003,-0.025643951,-0.026872741000000002,-0.017836169,-0.069411888,-0.771829807,-1.8262116819999998,-2.150946137,-2.3384304119999997,1.910193482,1.3923981019999998,,,,,,,,,-2.3761332035064697,-0.5392060279846191,-1.2551310062408447,-0.30835413932800293,-2.514589309692383 -4988,4988,W286N,-0.009794482,-0.054397613,-0.264041511,-1.887312939,-2.584006677,0.00829173,0.050642488,-0.070231451,-0.111642845,-0.087972897,-0.020822329,-0.150411309,-0.37767171299999996,-1.9254825309999999,-1.849143346,-2.408711269,-2.7593020839999998,1.039487314,0.6816141170000001,,,,,,,,,-6.556141376495361,-2.5466578006744385,-3.6657981872558594,-3.1542534828186035,-4.353952884674072 -4989,4989,W286Q,-0.051180388,-0.067660309,-0.263159765,-1.6721096709999999,-2.699394131,-0.042502924000000004,-0.024774867000000002,-0.07758590900000001,-0.058757725,-0.064868185,-0.070452432,-0.148447114,-0.377872415,-1.297221353,-2.046997988,-2.043691526,-3.355096735,2.656661711,1.752924673,,,,,,,,,-6.035090923309326,-2.3796377182006836,-3.250454902648926,-2.806901454925537,-4.168534278869629 -4990,4990,W286P,-0.020773802,-0.032204064,-0.6790091979999999,-1.774133056,-2.793520382,0.027337507,0.020801137,-0.06234874,-0.046381871,-0.052928428,-0.011479699,-0.244191035,-1.11382736,-1.6278887290000001,-1.9203773819999999,-2.550450161,-3.036590602,1.295336592,0.7582032409999999,,,,,,,,,-6.918371677398682,-2.2492690086364746,-3.8925437927246094,-3.044278144836426,-4.355480194091797 -4991,4991,W286S,-0.035005545,-0.110906583,-1.368383906,-2.347502246,-2.967712254,0.049699476,0.0037133979999999997,-0.073724487,-0.06176882400000001,-0.024788285,-0.197024881,-1.037578575,-1.699189236,-2.405870928,-2.289133564,-2.463130933,-3.4722935739999996,0.891281326,0.140268785,,,,,,,,,-5.655357360839844,-1.4393904209136963,-2.522268295288086,-1.7585417032241821,-3.308753490447998 -4992,4992,W286R,-0.025876952999999998,-0.012934593000000001,-0.853983933,-1.902060668,-2.7077312589999996,0.021912026,0.006036589,-0.057790495,-0.080176346,-0.039498408,0.013629222,-0.366959649,-1.341008217,-1.8013862669999998,-2.0027350680000002,-2.381525018,-3.033937499,1.49838426,0.7607122070000001,,,,,,,,,-5.75900411605835,-2.427201986312866,-3.489258289337158,-3.510688304901123,-4.424638748168945 -4993,4993,W286T,-0.072448841,-0.120705141,-1.316637014,-2.070245121,-2.8064217439999997,0.046943739000000005,-0.00630607,-0.138591611,-0.074702488,-0.012398127,-0.229012154,-1.0228292620000001,-1.6104447659999999,-1.9290357219999998,-2.211454519,-2.3800797769999997,-3.23276371,3.111094417,1.695993707,,,,,,,,,-6.145995140075684,-1.6733269691467285,-2.870354413986206,-2.1732258796691895,-3.702153205871582 -4994,4994,W286V,-0.015917203,-0.03684768,-0.943010715,-1.866516117,-2.813837323,0.02721362,0.029899297999999998,-0.061733704,-0.038513113,-0.039365157000000005,-0.034330203,-0.524840289,-1.3611811409999999,-1.8179913730000001,-1.915040861,-2.535303317,-3.092371328,1.76202265,0.824707313,,,,,,,,,-5.076356410980225,-2.111337423324585,-2.0482563972473145,-1.8654409646987915,-3.9970531463623047 -4995,4995,W286Y,-0.05769650900000001,-0.051533859,-0.03460837,-0.043875017,-0.9623609540000001,0.06759620599999999,-0.019271041000000003,-0.096121977,0.02454355,-0.016550427,-0.086517291,0.006978828,-0.076195567,-0.085645488,-0.002104546,-0.681236407,-1.2434855009999999,1.283680001,1.601609905,,,,,,,,,-4.371053218841553,-2.822263717651367,-2.055429458618164,-3.1094298362731934,-4.216367244720459 diff --git a/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled_masked.csv b/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled_masked.csv deleted file mode 100644 index 1376b98..0000000 --- a/esm/variant-prediction/examples/BLAT_ECOLX_Ranganathan2015_labeled_masked.csv +++ /dev/null @@ -1,4997 +0,0 @@ -,Unnamed: 0,mutant,0,39,156,625,2500,cefotaxime,0_1,0_2,10_1,39_1,39_2,156_1,156_2,625_1,625_2,2500_1,2500_2,km,vmax,mutation_effect_prediction_vae_ensemble,mutation_effect_prediction_vae_1,mutation_effect_prediction_vae_2,mutation_effect_prediction_vae_3,mutation_effect_prediction_vae_4,mutation_effect_prediction_vae_5,mutation_effect_prediction_pairwise,mutation_effect_prediction_independent,esm1v_t33_650M_UR90_1 -0,0,H24C,0.022702344,0.045890139,-0.025738193,0.018871156,-0.418259925,-0.031940758,-0.037094619,0.08249930700000001,0.002591313,-0.042346297000000005,0.134126575,-0.010196878000000001,-0.041279508,-0.014684342,0.052426653,-0.31935651800000003,-0.517163332,0.785765464,1.5199638519999998,,,,,,,,,-1463.3113127416 -1,1,H24E,0.011387119,-0.012635759,-0.018954701,-0.0204358,-0.279024169,0.016456013999999998,0.013497391000000001,0.009276846,0.054103653,-0.01967789,-0.005593628000000001,0.0015707420000000002,-0.039480144,-0.034798015,-0.006073584,-0.200042482,-0.358005855,0.757582777,1.502589239,,,,,,,,,-1463.7487980062142 -2,2,H24D,0.042301356,0.017005294,0.018951436000000002,0.006742876,-0.18160661,-0.030325921000000002,0.033849314,0.050753398,0.0027643740000000004,-0.0074014580000000005,0.041412046,0.017489834,0.020413037,-0.02608598,0.039571732000000005,-0.155937758,-0.20727546100000002,0.763289728,1.622027556,,,,,,,,,-1460.3104797499254 -3,3,H24G,0.01146042,-0.024511458,-0.023807149,-0.01720911,-0.060241672999999996,-0.009657341,-0.00047182699999999997,0.023392666,-0.013742003000000001,-0.040919201,-0.008103714,-0.02192628,-0.025688017999999996,-0.028224614,-0.006193606,-0.043527004,-0.076956341,1.099627807,1.7369408569999998,,,,,,,,,-1461.030880289618 -4,4,H24F,0.020598952,0.020320945,-0.015905298000000002,0.016190193000000002,-0.8184870959999999,-0.0008093110000000001,0.021397398999999998,0.019800504,-0.0015906879999999998,-0.045411124000000004,0.086053014,-0.01345311,-0.018357485,-0.008856131,0.041236516,-0.493981846,-1.142992345,1.074944348,1.5749229180000002,,,,,,,,,-1464.1345106051303 -5,5,H24I,0.008072384,-0.002722445,-0.039291543,-0.00968701,-0.359191243,-0.009312377,-0.0016294979999999998,0.017774265,-0.068626848,-0.019115145,0.013670255,-0.032591788999999996,-0.045991295999999994,-0.027839389,0.008465369,-0.292563068,-0.42581941700000003,0.8479204020000001,1.5187357940000001,,,,,,,,,-1463.161176491063 -6,6,H24K,0.039887617,-0.002490981,-0.019397018999999998,0.00610538,0.014469576999999999,-0.003065117,0.052906255,0.026868977999999998,0.16419203599999999,-0.019079923999999998,0.014097962,-0.013887172,-0.024906865,-0.007384305999999999,0.019595066,0.029525026,-0.000585873,0.326024656,1.4161181809999999,,,,,,,,,-1465.5773561792448 -7,7,H24M,0.025373797000000003,0.012340427,0.024713301,0.028739506,-0.22478129300000002,-0.026146539,0.02684011,0.023907484,0.18267544100000002,-0.006794296,0.031475149,0.00551956,0.043907042,0.010168857,0.04731015400000001,-0.146503843,-0.303058742,1.110067341,1.8944240630000002,,,,,,,,,-1464.5655140266754 -8,8,H24L,-0.007130208000000001,-0.024791695,-0.011061763,-0.011754145,-0.480346576,-0.001964848,-0.010297589000000001,-0.003962826,0.00735616,-0.009807279,-0.03977611,0.009071989,-0.031195515,-0.006225547,-0.017282742,-0.306059807,-0.654633344,1.023505724,1.645245487,,,,,,,,,-1463.2129117399454 -9,9,H24N,0.007222492,-0.010835478,0.016865981999999998,0.007656296999999999,-0.043093163,-0.008911973,-0.002849495,0.017294478999999998,0.08085483,-0.010625522,-0.011045434,0.01749522,0.016236743999999997,-0.014733888,0.030046481,-0.006558291999999999,-0.079628033,0.9955250659999999,2.060699369,,,,,,,,,-1463.7723879641853 -10,10,H24Q,0.006029993000000001,-0.008585199,0.0049857190000000004,-0.016438516,-0.135568334,0.001497615,0.00969967,0.002360316,-0.013783367,-0.010388462,-0.006781935,0.011864976000000001,-0.0018935389999999999,-0.033507197999999995,0.000630166,-0.08476713400000001,-0.186369533,2.437793081,2.747970799,,,,,,,,,-1468.0667098793201 -11,11,H24P,-0.13387458300000002,-0.082345722,-0.072931638,-0.417904623,-1.010848138,0.67096666,-0.112957484,-0.15479168199999999,-0.744292983,-0.129206405,-0.035485037999999997,-0.084989922,-0.060873354000000005,-0.19933237,-0.636476876,-0.924415785,-1.097280491,2.983480558,2.7878750510000003,,,,,,,,,-1462.4981327606365 -12,12,H24S,-0.008154446999999999,-0.034115248,-0.020574225,-0.01582124,0.036166097,0.0027934640000000003,-0.024719945,0.008411051,-0.018904125,-0.030762357,-0.037468138,0.013887271999999999,-0.055035722,-0.013632758,-0.018009721,0.068115045,0.004217149,2.225154604,2.659353477,,,,,,,,,-1463.6229871339165 -13,13,H24R,0.01683236,-0.009190524,0.004127683,-0.004182925,-0.002526258,0.031088453999999998,0.017507484,0.016157236000000002,-0.079373389,-0.029775986,0.011394938,0.006579872,0.001675493,-0.023271806000000003,0.014905956000000001,-0.008315396999999999,0.0032628809999999996,1.5464736069999998,2.938183126,,,,,,,,,-1463.405362885911 -14,14,H24T,0.02039927,-0.01458811,-0.007601924,-0.0047955820000000005,-0.067187546,-0.022489462999999998,0.018380054,0.022418486,-0.00299271,-0.037083702999999996,0.007907483,-0.000237405,-0.014966443000000001,-0.016221578,0.006630414,-0.04873158,-0.08564351199999999,1.407678003,2.285347998,,,,,,,,,-1465.1320292102173 -15,15,H24W,-0.006307298,-0.000633045,-0.029192701,-0.010615592,-1.3475859609999998,-0.015026478000000001,-0.006286516,-0.00632808,-0.038247647999999995,-0.036022839,0.034756748999999997,-0.031301744,-0.027083657999999997,-0.030208582999999997,0.0089774,-0.999196822,-1.695975099,1.04687351,1.421552326,,,,,,,,,-1464.897925525438 -16,16,H24V,0.026710717999999998,-0.010529573,-0.005339989,0.006753803,-0.026874047,-0.005140612,0.022703225,0.03071821,0.05573437,-0.015589325,-0.005469821,-0.013335158,0.00265518,-0.013740954,0.02724856,-0.001619701,-0.052128392999999995,1.224564307,2.138393446,,,,,,,,,-1463.6110060214996 -17,17,H24Y,-0.021573751000000002,-0.047011483,-0.023488167999999997,-0.033551258,-0.88502515,-0.015438488,-0.030115287999999997,-0.013032213,-0.034730469,-0.048617680999999996,-0.045405285,-0.006905626,-0.04007071,-0.038534926000000004,-0.02856759,-0.5889599870000001,-1.181090312,1.9215416580000002,2.138059625,,,,,,,,,-1461.6851145029068 -18,18,P25A,-0.10386603800000001,0.001748125,-0.004218662,-0.053582423,-1.6425950930000002,0.120518217,-0.083327717,-0.124404359,0.014370958,0.034530088,-0.031033839,0.032673877000000004,-0.041111199999999994,-0.036225351,-0.070939495,-1.430707001,-1.854483185,2.467386436,2.150571057,,,,,,,,,-1467.4087081863545 -19,19,P25C,-0.035211365,0.08671240300000001,-0.06833471099999999,0.009652236,-0.364138405,0.12798769999999998,-0.020434406000000002,-0.049988324,-0.054549701,0.101310071,0.072114734,-0.191309107,0.054639685,0.047170985,-0.027866513,-0.195560504,-0.532716305,1.9294107,2.312449074,,,,,,,,,-1461.7857399662025 -20,20,P25E,-0.011457153999999999,0.041199839,-5.429999999999999e-05,-0.010716763999999998,0.143257861,0.111450601,0.02865962,-0.051573928,-0.074597621,-0.01477754,0.09717721800000001,-0.00321029,0.00310163,-0.008045502,-0.013388026,0.149960974,0.136554748,1.590983034,3.812283434,,,,,,,,,-1458.9248798512854 -21,21,P25D,0.004797193,0.025658574,-0.060980488,-0.037705233,-0.028402505,0.046607841,-0.006968291,0.016562676999999998,-0.029385042000000004,0.006194666,0.045122482,-0.06390813099999999,-0.058052845,-0.028843079,-0.046567387,0.016735672,-0.073540682,1.165591923,1.75016223,,,,,,,,,-1460.4449101686478 -22,22,P25G,-0.02390934,0.00857487,0.02089776,-0.007906311999999999,-0.969267861,0.039196438,-0.01376224,-0.034056439,0.015377403000000001,-0.013636435,0.030786175,0.0070737280000000005,0.034721791,-0.011556967,-0.004255656,-0.649078606,-1.289457116,1.174220101,1.5674038019999998,,,,,,,,,-1460.2627324960195 -23,23,P25F,-0.012487661,-0.042772745,0.07568559799999999,0.033886087999999995,-0.19980403100000002,0.066925464,-0.049121473,0.024146152,0.10149363800000001,0.003571726,-0.089117216,0.083675768,0.067695427,0.024388933999999998,0.043383240999999996,-0.137551135,-0.262056927,0.9640241759999999,1.7040422309999999,,,,,,,,,-1462.1638930509798 -24,24,P25I,-0.028071818,0.024272005,0.016421708,0.02703638,-0.073523836,0.021876117,0.048925754,-0.10506939,-0.04549523900000001,0.030187245,0.018356763999999998,0.070782746,-0.037939331,0.001924393,0.052148365999999995,-0.047404682000000004,-0.09964299,0.49533926100000003,1.521717066,,,,,,,,,-1462.3632800420746 -25,25,P25H,0.029477972999999998,0.040318718999999996,0.06397124900000001,0.07258627,0.045784618,0.07333674,0.013637671,0.045318274000000006,-0.0032417120000000003,0.074293521,0.006343916,0.08378065700000001,0.04416184099999999,0.137057045,0.008115495,0.10669228300000001,-0.015123046999999999,0.39783476799999995,1.463720776,,,,,,,,,-1464.3008427070454 -26,26,P25K,-0.066288891,0.11725209199999999,0.009166947,0.072576088,0.135590499,0.020043081,-0.02721235,-0.105365432,-0.006021205999999999,0.116714876,0.11778930800000001,0.042032785999999996,-0.023698892000000003,0.154531417,-0.009379241,0.153679558,0.11750144,0.8460874890000001,1.542000952,,,,,,,,,-1461.0005278042518 -27,27,P25M,-0.09282261,0.029051416,0.006452596999999999,0.039816967,-0.02836574,0.050932846,-0.052520568,-0.13312465099999998,0.040635807999999995,0.050526799000000004,0.007576032,0.060013935,-0.047108740999999996,0.11788607400000001,-0.03825214,0.010015825,-0.066747305,0.188973702,1.759942865,,,,,,,,,-1452.738453054335 -28,28,P25L,-0.005307256,0.002001949,0.011836247,0.008659517,-0.211868922,0.064513297,-0.002101309,-0.008513203,0.015368952,0.00376092,0.00024297700000000002,-0.002386983,0.026059476,0.04727512,-0.029956087000000003,-0.122705077,-0.301032767,1.945234964,2.369792706,,,,,,,,,-1460.1487515829504 -29,29,P25N,-0.051559887,0.039733466,0.070335003,0.004724437,0.020640486,0.036064768999999997,0.031452377000000004,-0.13457215,-0.027886684,-0.035975711,0.115442642,0.031178817999999997,0.10949118699999999,0.01069026,-0.001241387,0.014249976999999999,0.027030995,1.104388073,2.143068318,,,,,,,,,-1464.0574032114819 -30,30,P25Q,0.138010463,0.011568189,0.063431807,0.10837302900000001,-0.028213622,0.07860940200000001,0.091898126,0.18412279899999998,0.032167147,0.021135016,0.002001361,0.020337831,0.106525782,0.064379082,0.152366976,-0.019924656000000002,-0.036502587,1.208210385,2.58900106,,,,,,,,,-1463.9184366269037 -31,31,P25S,-0.039348434,0.004380082,-0.0039446590000000005,-0.018238771,-0.160130436,0.030006567,-0.013738251000000002,-0.064958616,-0.055818152,-0.026092677999999998,0.034852842,0.018987832,-0.026877149,0.006671651,-0.043149192,-0.150924537,-0.169336335,1.406720565,2.237189096,,,,,,,,,-1465.6215008753352 -32,32,P25R,-0.013706154,0.005957286,-0.014669933000000001,-0.046117530999999996,0.054153993,0.156314831,-0.000248097,-0.02716421,-0.089279396,-0.021879775,0.033794347,-0.029032602,-0.000307263,-0.098906076,0.006671015,-0.0028679779999999998,0.111175963,1.251916214,2.535180898,,,,,,,,,-1458.415501784999 -33,33,P25T,-0.076933927,-0.007848001,-0.006919319,0.0010241360000000001,-0.091199948,0.000353426,-0.026131054,-0.127736799,-0.017982202,0.00335265,-0.019048652,-0.009112019,-0.004726618,0.013580426999999999,-0.011532155,-0.04988034,-0.13251955599999998,1.24094672,2.425970024,,,,,,,,,-1464.4649031776935 -34,34,P25W,0.013600484,0.050044448,0.073206825,0.029595033,-0.109138595,0.030245566,-0.0032214559999999997,0.030422422999999997,0.0039723729999999995,0.061866422000000004,0.038222474,0.024107117999999997,0.122306531,0.045284397000000004,0.013905668000000001,-0.051122111,-0.167155079,1.169687228,2.435839065,,,,,,,,,-1458.8198611410335 -35,35,P25V,-0.027791512999999997,0.025620063,0.022951329,-0.010637381999999999,0.04591299099999999,0.100840981,-0.022572752,-0.033010274,-0.052321226,0.014312122,0.036928004,0.015046283999999998,0.030856374,-0.011038731000000001,-0.010236033,0.047570830999999994,0.04425515,1.1290397890000001,2.788424151,,,,,,,,,-1461.4123219647445 -36,36,P25Y,-0.094727201,-0.008258924,-0.022609935,-0.03167515,0.0017446679999999998,-0.082969713,-0.136345006,-0.053109395,0.015099743999999998,-0.0036885679999999997,-0.01282928,0.029174482999999998,-0.074394353,-0.013321733,-0.050028567,-0.0063045490000000004,0.009793885,1.2289840570000001,2.5370460969999997,,,,,,,,,-1458.7884226012975 -37,37,E26A,-0.060088714,0.035019974,0.046008999999999994,0.07483489900000001,0.010913108000000001,0.07026014900000001,-0.06167179,-0.058505638,0.090042438,-0.011974944,0.082014892,0.03097157,0.061046429000000006,0.023863482000000002,0.125806315,-0.011478437,0.033304653,1.2204184059999998,2.754342831,,,,,,,,,-1465.2131188423373 -38,38,E26C,0.051185296,0.08338335200000001,0.07888178700000001,0.072504124,-0.158232612,-0.067113079,0.061477542999999996,0.040893049,0.147844696,-0.0041502859999999996,0.17091699,0.024473769,0.133289805,0.031847367,0.11316088,-0.147334969,-0.16913025399999998,1.319927096,2.178389478,,,,,,,,,-1464.7080218736082 -39,39,E26D,-0.134622252,-0.048278454000000005,0.029866107000000003,0.027840852000000003,-0.07578524,0.083496095,-0.12736836199999998,-0.14187614199999998,0.08222078299999999,-0.128399269,0.031842361,0.049190665999999994,0.010541547,-0.009290076,0.06497178,-0.073498399,-0.078072081,1.160453271,2.203032084,,,,,,,,,-1462.3888127841055 -40,40,E26G,0.074308788,0.223560228,0.17184728800000001,0.179592065,0.08131007700000001,-0.027626518,0.012129959,0.136487616,0.172252043,0.146756386,0.30036407,0.16478736800000002,0.17890720699999998,0.13317435,0.226009779,0.06361610200000001,0.099004051,1.189518643,2.987475843,,,,,,,,,-1462.4204064765945 -41,41,E26F,-0.020927228,0.052075812,0.062112092,0.085250613,-0.232106116,-0.10336064,-0.017165364,-0.024689091,-0.06504592099999999,0.065483923,0.0386677,0.113509275,0.010714908,0.12774971400000001,0.042751512,-0.091720963,-0.372491268,1.1686604999999999,2.305963479,,,,,,,,,-1464.6678362996317 -42,42,E26I,-0.04678198099999999,0.08923668400000001,0.089213575,0.103174965,-0.153907493,-0.044398892,-0.072168265,-0.021395696000000002,0.130412738,0.07330538,0.10516798699999999,0.08943488,0.088992269,0.117652059,0.08869787,-0.138097757,-0.169717228,1.252476759,2.191690605,,,,,,,,,-1467.4732296089642 -43,43,E26H,-0.043425119000000005,0.082855565,0.083513347,0.114422615,0.020916837,0.010849126,-0.086416719,-0.00043351800000000003,0.07944541,0.049495962000000004,0.11621516800000001,0.085745016,0.081281677,0.113490903,0.11535432699999999,0.025989434,0.015844239,1.261017122,3.025741946,,,,,,,,,-1463.857669163961 -44,44,E26K,-0.038926874,0.058490223,0.039393067999999996,0.08651887800000001,0.087119809,0.041040865,-0.046154832,-0.031698916,0.154969402,-0.0632611,0.180241545,-0.001884144,0.08067028,0.018855342,0.154182414,0.011954356999999999,0.16228526,1.090470615,2.610276223,,,,,,,,,-1462.4817384970374 -45,45,E26M,-0.022183283999999998,0.074443098,0.09094756,0.118748545,-0.036440986,-0.053481152000000004,0.011119258,-0.055485825,0.306981506,0.08346328900000001,0.065422907,0.145623335,0.036271785,0.130202977,0.10729411300000001,-0.005214771,-0.067667201,1.218124703,2.7516917419999998,,,,,,,,,-1465.1487503782846 -46,46,E26L,0.010543748,0.08294438900000001,0.076037929,0.091447172,-0.05818041,-0.021525499,0.000614657,0.020472838,0.099935417,0.003116839,0.162771939,0.048573675999999996,0.103502182,0.004616994,0.17827735,-0.079421767,-0.036939052,1.135646515,2.2157617259999998,,,,,,,,,-1466.293306632433 -47,47,E26N,-0.031657324,0.060627192,0.091066853,0.039984992000000004,-0.006468796999999999,-0.053321327,-0.04427469999999999,-0.019039948,0.229094262,-9.49e-05,0.121349284,0.127210553,0.054923152999999995,-0.013103046,0.093073029,0.018903217,-0.03184081,1.204694658,2.929347525,,,,,,,,,-1463.4073592834175 -48,48,E26Q,-0.020517156,0.08404489,0.04875523,0.064826026,0.049690653,-0.005371125,0.000764699,-0.041799011000000004,-0.00472684,0.098069679,0.070020101,0.100251745,-0.002741286,0.08672771,0.042924342000000004,-0.047413247,0.146794553,1.215644385,2.5650320769999997,,,,,,,,,-1465.5570451696403 -49,49,E26P,-0.013258715,0.093119437,0.069852749,0.066757808,-0.387232365,-0.010640993999999999,-0.020444549,-0.00607288,0.121882909,0.034911035,0.15132783800000002,0.048987795,0.090717702,0.028017465,0.105498151,-0.323835808,-0.45062892200000004,0.8622878490000001,1.5888088130000002,,,,,,,,,-1460.7414813842624 -50,50,E26S,0.008822045,0.062530196,0.084343423,0.066269137,-0.039584928,-0.00190877,0.015906523,0.001737566,0.093909764,0.01396951,0.111090881,0.037997407000000004,0.130689439,0.018650728000000002,0.11388754599999999,-0.063170402,-0.015999453,1.425051198,2.4730023969999997,,,,,,,,,-1463.4837323040701 -51,51,E26R,-0.034878101,0.064167344,0.056959895999999996,0.064815187,-0.220002694,0.055094485,-0.04941712,-0.020339081999999998,0.06200121,0.001093115,0.127241572,0.019034356000000002,0.094885435,0.016606558,0.113023815,-0.233019957,-0.20698543,1.216399974,1.927173917,,,,,,,,,-1458.9814366050996 -52,52,E26T,-0.068693308,0.067196764,0.091103084,0.06558067299999999,-0.135908892,-0.047085287,-0.082941395,-0.054445220999999995,0.140445519,0.040813172,0.09358035599999999,0.113968603,0.068237565,0.063663484,0.06749786099999999,-0.126344867,-0.14547291699999998,1.342091145,2.282051505,,,,,,,,,-1464.6774761443958 -53,53,E26W,-0.077143388,0.078134304,0.13106215599999999,0.05794898,-0.442340179,-0.007556826,-0.099702913,-0.054583862999999996,0.127188408,0.107484662,0.048783945,0.158286969,0.10383734300000001,0.076026447,0.039871512000000005,-0.282806958,-0.601873399,0.753185228,1.5744139519999998,,,,,,,,,-1463.6486055240966 -54,54,E26V,-0.021916136,0.116771963,0.09809352199999999,0.07620685599999999,-0.06456742900000001,0.053498727999999995,0.0013647870000000001,-0.045197059000000005,-0.005312536999999999,0.054057513,0.17948641199999998,0.095287693,0.10089935,0.063602831,0.08881088,-0.0759068,-0.053228057,1.14355857,2.2914504630000003,,,,,,,,,-1467.3894581547938 -55,55,E26Y,-0.050049098,0.056360349000000004,0.082999386,0.068513351,-0.245436276,0.008291246,-0.053024215,-0.04707398,0.16999146899999998,0.029324085,0.083396613,0.065728571,0.1002702,0.026829566000000003,0.110197135,-0.13169476800000002,-0.359177783,1.238381025,2.122608572,,,,,,,,,-1462.0411166693084 -56,56,T27A,0.01357957,0.039949606,0.057111746,0.013452565,-1.4545883080000002,0.032397485,0.017141401,0.010017739,-0.035744448,0.005885989,0.074013222,0.050484312999999996,0.063739178,0.038931638,-0.012026509,-1.3270744909999999,-1.582102125,0.584924165,1.322045675,,,,,,,,,-1462.317841479089 -57,57,T27C,0.018866531000000002,0.064055143,0.05501894400000001,-0.16464778900000002,-2.419022561,-0.02408756,-0.000750725,0.038483787,-0.087721879,0.025631016,0.10247927,0.074124041,0.035913847,-0.064575672,-0.264719906,-1.851261728,-2.9867833939999997,0.7824591359999999,1.307603573,,,,,,,,,-1465.354044528678 -58,58,T27E,-0.060106353,-0.035422838,-0.7334358529999999,-2.0218939430000002,-2.414464268,-0.084510018,-0.055243239000000006,-0.06496946599999999,-0.05644945,-0.028293325,-0.042552350999999995,-0.340185302,-1.126686403,-1.937002238,-2.1067856469999997,-2.048521205,-2.780407331,1.6019825730000001,0.765758664,,,,,,,,,-1458.7470651897602 -59,59,T27D,-0.052200116,-0.017669463,-0.013005533,-1.445405769,-2.29488302,0.05915248,-0.034762106,-0.069638126,-0.036020585,-0.008402157,-0.026936769,-0.017412133,-0.008598933000000001,-0.8905929370000001,-2.0002186,-1.961683246,-2.628082794,2.181692184,1.551446707,,,,,,,,,-1457.93329977151 -60,60,T27G,-0.05851333,0.071181742,-0.028860278,-1.681217301,-2.356711536,-0.01488177,-0.058640051,-0.058386609000000006,-0.07887849799999999,0.081791089,0.060572394,-0.002275716,-0.05544484,-1.3868884469999998,-1.975546154,-2.206922736,-2.506500335,0.772049338,0.719134598,,,,,,,,,-1461.2657602853142 -61,61,T27F,-0.046006795999999996,-0.03043394,-0.012103451000000001,-1.582760741,-2.604569889,-0.046856321,-0.045534145,-0.046479447,-0.09075764900000001,-0.023318534,-0.037549346000000004,0.027109167000000003,-0.051316068,-1.1836745709999998,-1.98184691,-2.3495512,-2.859588577,0.969364977,0.766731288,,,,,,,,,-1465.7718067709357 -62,62,T27I,0.023747147000000003,0.051240129,0.075382693,0.023093952999999997,-0.280445552,0.004405203,0.002991707,0.044502587,0.054869759000000004,-0.008443589,0.11092384599999999,0.032435341,0.11833004400000001,0.068619705,-0.022431799,-0.213844297,-0.347046807,1.131320058,1.907965161,,,,,,,,,-1466.8455519718118 -63,63,T27H,-0.025521534,0.054516839000000004,0.033160455,-0.247634362,-1.849536455,-0.015516528,-0.023085744,-0.027957324,-0.050290329,0.063741083,0.045292595,0.042622928,0.023697982000000003,-0.20539605600000002,-0.289872668,-1.689638244,-2.009434665,1.203319712,1.354291673,,,,,,,,,-1462.4935439582914 -64,64,T27K,-0.012258317,0.09458871699999999,0.071384172,-0.694698492,-1.4278894359999998,0.031149431,-0.019092941999999998,-0.005423691,-0.036900614,0.072726807,0.116450626,0.107292716,0.035475627999999995,-0.37558086799999996,-1.0138161159999999,-1.089159826,-1.766619046,1.957469488,1.817070819,,,,,,,,,-1458.1863481085747 -65,65,T27M,0.023298222,-0.035811291,-0.049022294,-0.077604075,-1.84309581,-0.029550233999999998,0.010939986,0.035656457999999995,-0.091258277,-0.10585133099999999,0.03422875,-0.057910141,-0.040134447000000004,-0.117289611,-0.037918539,-1.7138987630000002,-1.9722928569999998,1.091363095,1.3386923579999999,,,,,,,,,-1468.1749884858727 -66,66,T27L,-0.00520012,0.020403634,0.020395353999999997,-0.002497664,-0.7655211470000001,0.0071649190000000005,-0.008171017,-0.0022292220000000003,-0.034990466,0.015732065,0.025075202,0.052401689,-0.011610981999999999,0.010565294,-0.015560621,-0.5231183420000001,-1.007923952,0.64180557,1.41243685,,,,,,,,,-1467.3340406706557 -67,67,T27N,-0.018373965,0.05123653400000001,0.07067300900000001,-0.5670000470000001,-2.4857249219999997,-0.00692772,-0.004454341,-0.032293589,-0.000322741,0.025715797000000002,0.076757271,0.09308630300000001,0.048259715,-0.24550338600000002,-0.888496708,-2.154058947,-2.8173908969999997,1.21450464,1.303342199,,,,,,,,,-1462.733953335788 -68,68,T27Q,-0.019357507,0.038441852,0.021874675,-0.011546786000000002,-1.6670994369999999,0.007096191999999999,-0.0037087709999999996,-0.035006243,-0.03898183,0.021153712999999998,0.055729991,0.0038834570000000003,0.039865892,0.012561832,-0.035655404,-1.7720804819999998,-1.562118392,0.638912085,1.305582282,,,,,,,,,-1462.8541560079902 -69,69,T27P,-0.012825537,0.040221632,0.03461181,-0.063710394,-1.7901721609999999,0.000370384,-0.0092243,-0.016426773999999998,-0.061390324,0.033592459,0.046850804,0.050711808,0.018511812,-0.05115901,-0.076261777,-1.6082035559999999,-1.9721407659999999,0.8302584340000001,1.32360325,,,,,,,,,-1464.0065149967559 -70,70,T27S,0.000828692,0.032511543999999996,0.037237365,0.00384456,-1.3924781480000001,-0.017822742,0.000763483,0.0008939,-0.133810627,-0.0009215369999999999,0.065944625,0.065397336,0.009077393000000001,0.047014477,-0.039325358,-1.0451304259999998,-1.73982587,0.7050011959999999,1.3516310390000001,,,,,,,,,-1463.3644208502956 -71,71,T27R,-0.040271839,0.013151862,0.052985915,-1.400772418,-2.375093809,0.008316061999999999,-0.013639617,-0.06690406,-0.077932789,-0.008145178000000001,0.034448901000000004,0.052096931,0.053874898,-0.994384024,-1.807160811,-2.093313864,-2.6568737540000003,2.059162141,1.438641087,,,,,,,,,-1458.0088236518204 -72,72,T27W,-0.079957782,-0.061488913,-1.224764296,-2.259024869,-2.841700815,-0.050100115,-0.069489008,-0.09042655599999999,-0.176269066,0.021794295,-0.14477212,-0.999039171,-1.45048942,-1.557633469,-2.9604162689999995,-2.748333681,-2.9350679489999996,2.414287908,1.200072427,,,,,,,,,-1465.681592640467 -73,73,T27V,0.017138814,0.054112503,0.024078477,0.023495206,0.034189274,0.026123253,-0.013076521,0.047354148,-0.09869385,0.051003292,0.057221713,0.05185309999999999,-0.003696146,0.04636486,0.0006255519999999999,0.068248893,0.000129655,1.000995395,2.750605849,,,,,,,,,-1466.140666399151 -74,74,T27Y,0.05417784900000001,-0.003139565,-1.082915309,-2.411546054,-2.7891347680000003,-0.043960803,0.06320822,0.045147478,-0.1212215,0.014089733,-0.020368863,-0.882236272,-1.2835943459999999,-1.795487707,-3.027604401,-2.576013455,-3.00225608,2.330971542,1.093527199,,,,,,,,,-1462.7189126340672 -75,75,L28A,-0.019704668999999998,0.035900647,-0.003939622,0.027649035,-0.20222814,0.008399527,-0.008430686,-0.030978651,0.052565441,0.0017858000000000001,0.070015493,-0.022677388,0.014798145,0.040500106,0.014797963999999999,-0.173805337,-0.230650943,1.412477244,2.1439149769999997,,,,,,,,,-1467.6118107982911 -76,76,L28C,-0.032813414,-0.04765922400000001,-0.024893669,0.019473818,-1.95959115,0.033836026,-0.009628844000000001,-0.055997983,-0.03776968,-0.08166427799999999,-0.013654168999999999,-0.050404055,0.000616718,0.012688293,0.026259342,-1.363123509,-2.556058791,0.5280298170000001,1.317636037,,,,,,,,,-1464.730840132106 -77,77,L28E,-0.053680802,-0.027822315,0.005018305,0.034194381,-1.721637749,0.062170051,-0.060300458,-0.047061146,0.011197743000000001,-0.039050066,-0.016594563,-0.039229596,0.04926620599999999,0.029358607000000002,0.039030155,-1.548735466,-1.894540031,0.5975315179999999,1.313976786,,,,,,,,,-1467.857518590521 -78,78,L28D,-0.038487142,0.034237114,0.001944002,-1.5040970790000001,-2.71076857,0.048642849,-0.026580588,-0.050393695999999995,0.018490153999999998,-0.004092048,0.072566276,-0.002845629,0.006733633,-1.1970689890000001,-1.811125169,-2.558354537,-2.8631826030000003,0.8629072879999999,0.747605855,,,,,,,,,-1467.496919322759 -79,79,L28G,-0.022334179,-0.03150269,0.003770012,0.03978715,-1.484204085,0.020863209,-0.011678121999999999,-0.032990235,0.053555499000000006,-0.023316037999999997,-0.039689341,-0.035205275,0.042745299,0.012310173999999998,0.067264126,-1.400435145,-1.567973024,0.669484861,1.324566055,,,,,,,,,-1463.9345471221022 -80,80,L28F,-0.040002993,-0.070440371,-0.037635603,0.015112183000000001,-0.720047067,-0.038578852999999996,-0.027566088,-0.052439897,0.013702084,-0.041360041,-0.0995207,-0.125446168,0.050174962000000004,-0.019745599,0.049969965,-0.554762104,-0.88533203,1.302795467,1.682510683,,,,,,,,,-1461.5719712763093 -81,81,L28I,0.048150385999999996,-0.022671011,-0.003042581,-0.00309151,0.017395788,-0.025860834,0.088786579,0.007514191999999999,-0.05013022,-0.025007758999999997,-0.020334262,-0.05534956,0.049264399,-0.015137646000000001,0.008954627,0.027656387,0.007135189,1.2003354529999999,2.680567088,,,,,,,,,-1463.2582587171346 -82,82,L28H,-0.008017467,0.032561265,0.047690945,0.070178796,-0.889277008,-0.008464177,0.01538669,-0.031421622999999996,0.119941152,0.042575509000000004,0.022547021,0.045516028,0.049865861,0.081971662,0.05838593,-0.585200101,-1.193353914,0.39779746200000005,1.3603801469999999,,,,,,,,,-1466.9735303036869 -83,83,L28K,-0.005539491,-0.002878644,0.028632087999999997,0.059325622,0.069595673,0.10400271,-0.014369258999999999,0.0032902779999999998,-0.052811494,-0.033428372000000005,0.027671084,0.034333273,0.022930902000000003,0.059881153,0.058770090999999997,0.04615663,0.09303471599999999,1.154452356,2.8282529160000003,,,,,,,,,-1467.5662105698138 -84,84,L28M,-0.041787101,-0.049764660999999995,0.002258615,-0.00526688,-0.04806969999999999,0.025590638,-0.035141813,-0.048432389000000006,0.11083494599999999,-0.008616484,-0.09091283800000001,-0.008083692,0.012600921000000001,-0.027921638999999998,0.017387879,-0.033204382000000005,-0.062935017,1.214121872,2.476624221,,,,,,,,,-1464.1434765937738 -85,85,L28N,-0.035726656,0.023491101,0.015489448000000001,0.05982907,-1.4207135380000002,0.032766647999999995,-0.032235555,-0.039217756,-0.083636957,0.027469676000000002,0.019512526000000002,0.026470652,0.0045082429999999995,0.053052552999999995,0.06660558700000001,-1.120972321,-1.720454755,0.648017497,1.341582467,,,,,,,,,-1467.2586014624685 -86,86,L28Q,-0.056036688,0.007080485,-0.0020201010000000003,0.045650558,-0.222811812,0.034851675,-0.055223318,-0.056850057999999995,0.007987811,0.043285528,-0.029124558,-0.006053269,0.0020130670000000003,0.04749584,0.043805275,-0.16291523800000002,-0.282708385,1.299823672,2.151609564,,,,,,,,,-1468.6611089031212 -87,87,L28P,-0.007785696999999999,0.004923397,-0.015633364,-0.897614543,-2.195354681,0.002928139,0.007419172,-0.022990565,0.046125877,-0.041566146,0.051412939000000005,-0.071990234,0.040723506,-0.482904325,-1.31232476,-2.039768688,-2.350940673,1.6487854240000002,1.3762643680000002,,,,,,,,,-1464.0526095414534 -88,88,L28S,-0.030663797000000003,-0.019146217,-0.035706727,-0.007251026999999999,-1.264096226,0.024712166,-0.02469844,-0.036629154,0.057383265,-0.054752904000000005,0.01646047,-0.083555676,0.012142222,-0.04799515099999999,0.033493098,-1.073604209,-1.4545882430000001,0.973728461,1.391577557,,,,,,,,,-1467.1314400928095 -89,89,L28R,-0.01000016,-0.012317896000000002,0.000608244,0.011852271000000001,-0.064935717,-0.002833226,-0.011642725,-0.008357594,0.016334951,-0.017567512,-0.00706828,-0.021453702999999998,0.022670191,0.008084394,0.015620147,-0.063067001,-0.066804433,1.236790042,2.2838463780000002,,,,,,,,,-1464.2697284072638 -90,90,L28T,-0.001606327,0.014496056,0.001228926,0.003866305,-0.31365641899999996,-0.009803708000000001,-0.009859284,0.00664663,0.048529660999999995,-0.0022474179999999997,0.031239529,-0.021174838999999997,0.023632691,-0.006817963000000001,0.014550572,-0.24660265399999998,-0.380710184,1.4312701490000002,2.048091072,,,,,,,,,-1466.1890937429853 -91,91,L28W,-0.024043175,-0.053305583,-0.024093091,-0.005568071999999999,-0.29973849399999997,-0.053695544000000005,0.000671163,-0.048757512999999995,0.115608145,-0.108664755,0.0020535889999999998,-0.103328715,0.05514253400000001,-0.071816898,0.060680754,-0.276355435,-0.323121552,1.739425948,2.24294914,,,,,,,,,-1461.2048105471767 -92,92,L28V,-0.011099186,0.005321875,-0.010107739000000001,0.033466368999999996,0.0502655,0.00649983,-0.027822718,0.005624346999999999,0.113093607,-0.017248663,0.027892412000000002,-0.037449251,0.017233773,0.011705326,0.055227411,0.070190045,0.030340954,1.179595765,2.85762827,,,,,,,,,-1465.466759160161 -93,93,L28Y,-0.013498753,0.02340398,0.037875386000000004,0.049471904000000004,-0.218600359,0.053112228,0.025243257999999998,-0.052240762999999996,-0.004014579,0.024484456,0.022323502999999998,0.0017056579999999999,0.07404511400000001,0.075707921,0.023235887,-0.14341694800000002,-0.29378377,1.260382411,2.154641454,,,,,,,,,-1461.2000017208047 -94,94,V29A,0.03161015,-0.001833615,0.053258459,0.056550645,0.046784507999999995,0.023513221,0.019564078000000002,0.043656220999999995,-0.005949811,-0.006176664,0.002509434,0.050462148,0.056054769000000004,0.0012183889999999998,0.11188290099999999,0.067174145,0.026394871,1.0938907420000001,2.7654161110000004,,,,,,,,,-1461.9809578810818 -95,95,V29C,0.051793600999999995,0.056978617999999995,0.09845768099999999,0.10055774199999999,0.035059494,0.020501593000000002,0.06513113599999999,0.038456065,0.062122526,0.033926363,0.080030872,0.036764281,0.16015108,0.085099194,0.11601628900000001,-0.001241264,0.071360251,1.147656284,2.672187365,,,,,,,,,-1461.588535942603 -96,96,V29E,-0.076401493,-0.004996111,0.00256741,0.06816767,0.05100108,-0.006401378,-0.076764329,-0.076038656,-0.052261460999999995,0.077038756,-0.087030977,0.051682473,-0.046547653,0.07970068799999999,0.056634652,0.162227967,-0.060225808,1.0972676270000001,3.14722183,,,,,,,,,-1458.0689123682678 -97,97,V29D,0.123781935,0.020589661000000002,0.051152647999999995,0.070239921,0.04441326599999999,-0.019608718,0.082869227,0.164694643,-0.005051826,-0.030161045,0.071340367,-0.008918065,0.11122336,-0.06335455400000001,0.203834396,0.06671392400000001,0.022112608,1.068447199,2.7368904589999996,,,,,,,,,-1460.302437024191 -98,98,V29G,-0.000823415,0.013215538,0.033055424,0.040087412,0.040152735,0.013481811000000002,-0.009105045,0.007458215,-0.020173158,0.017056911,0.009374165,0.037141808,0.02896904,-0.005990934,0.08616575800000001,0.053927577000000004,0.026377893,1.076833718,2.62284945,,,,,,,,,-1461.3530435948633 -99,99,V29F,0.052479280999999996,0.01863507,0.06402548400000001,0.103727905,-0.060232139000000004,-0.021254013,0.048621732,0.05633683,-0.041556477,-0.021618786,0.058888925999999994,0.045415392,0.082635575,-0.015414473,0.222870283,-0.050873122,-0.069591156,1.236356625,2.385207366,,,,,,,,,-1459.9213721975684 -100,100,V29I,-0.050772924000000004,0.02059818,-0.036868409,0.06271859099999999,-0.013303233999999999,-0.072786189,-0.048780545,-0.052765302,-0.062777579,-0.004606941,0.0458033,-0.040687088999999996,-0.033049729,-0.006910895,0.13234807699999998,-0.0056038780000000005,-0.02100259,1.250835485,2.6210542169999997,,,,,,,,,-1461.6870039068162 -101,101,V29H,-0.014345746999999999,0.024843938,0.046788515999999995,0.017439621000000002,-0.014840417,-0.036869974,-0.039654776,0.010963282,-0.034660366,0.036259942999999996,0.013427932,0.032056213,0.061520819000000004,-0.007805357,0.042684599000000004,0.00354753,-0.033228363999999996,1.148125972,2.50576595,,,,,,,,,-1459.7908585700206 -102,102,V29K,-0.015901929,-0.021431138,0.034864865,0.030639455,0.036194098,-0.053390969,0.017719448,-0.049523305,-0.073212986,0.093542145,-0.136404421,0.063909753,0.005819976,0.054965492000000005,0.006313416999999999,0.09821175800000001,-0.025823562999999997,1.6804900280000001,3.618873133,,,,,,,,,-1458.4263342283666 -103,103,V29M,0.17816574,0.054498452,0.12375289199999999,0.18286428300000002,0.096017091,-0.101066501,0.20472521,0.15160626900000002,-0.062985326,0.048314605,0.060682299,0.02413368,0.223372104,0.06719994900000001,0.298528616,0.07798648700000001,0.114047695,1.0624351159999998,2.89406119,,,,,,,,,-1459.828638298437 -104,104,V29L,-0.000693695,0.011406346000000001,0.031761116,0.039559515,-0.01214075,-0.044949337,0.006982885,-0.008370274,-0.0072729990000000005,0.026452778,-0.003640087,0.060232925,0.003289307,0.011039334,0.068079695,0.025135912000000003,-0.049417410999999994,1.299873983,2.842602897,,,,,,,,,-1459.893527451437 -105,105,V29N,0.027439061,-0.027357327,0.014343378,0.065510499,0.051505842999999996,-0.12226369599999999,-0.024110671,0.078988792,-0.003789621,0.022812258999999998,-0.077526913,0.003826408,0.024860347,-0.003942495,0.13496349300000002,0.003093174,0.099918511,1.351575961,2.679081423,,,,,,,,,-1461.0287931277417 -106,106,V29Q,-0.02712337,0.006014605,0.042593005,0.026620047,0.021601685,-0.071417555,-0.04498626,-0.009260479,-0.072969547,0.008806063000000001,0.003223147,0.072550667,0.012635343,0.022296376,0.030943717000000003,0.021949461,0.021253908,1.14065731,2.699438039,,,,,,,,,-1459.935970949009 -107,107,V29P,-0.005682703000000001,0.006407446999999999,0.043631888,-1.3160347559999999,-2.3870484,-0.04179938,0.001345294,-0.012710700000000002,-0.039839861000000004,-0.00096412,0.013779014,0.042776875,0.044486900999999995,-0.872145464,-1.759924048,-2.311736352,-2.462360447,1.8679942840000001,1.312881145,,,,,,,,,-1459.1847858787514 -108,108,V29S,0.008664827,0.035151562000000004,0.061598774,0.07835551,0.008377766,-0.04583351099999999,-0.019010396000000002,0.036340049,-0.043936072,0.035392973,0.034910151,0.076166795,0.047030752,0.049495354000000005,0.107215666,0.033026829,-0.016271297,1.239467195,2.880565512,,,,,,,,,-1460.6602330403402 -109,109,V29R,0.007714585,-0.00501381,0.023897913,0.041116586000000004,0.065185473,0.070105522,-0.00035861599999999997,0.015787786,-0.049437077,-0.014894056000000001,0.004866436,0.011441043,0.036354782,-0.012543148999999998,0.09477632,0.066319154,0.064051791,1.097271519,2.8484196219999998,,,,,,,,,-1456.3014110797085 -110,110,V29T,0.021507369,0.05291894,0.040859774,0.05519914099999999,0.029703032999999997,-0.051098656,-0.011330593,0.05434533,-0.08968191199999999,0.041579133,0.06425874599999999,0.076970068,0.004749479,0.030212668999999998,0.080185612,0.059472965,-6.69e-05,1.57943243,3.5686812480000003,,,,,,,,,-1460.810717314016 -111,111,V29W,0.078299356,0.010157491,0.059404704,0.038858458,0.056414715,0.051696306,0.076785755,0.07981295599999999,-0.193038778,-0.02650755,0.046822532,0.03300026,0.08580914699999999,-0.044092725,0.12180964,0.039520486,0.073308943,1.182111691,2.640051708,,,,,,,,,-1459.4980954448693 -112,112,V29Y,0.013139012,-0.052346870999999996,0.060791209000000006,0.07316557900000001,-0.087401776,-0.092002091,-0.005883819,0.032161842999999996,0.032545243,-0.05719558,-0.047498161,0.035042749,0.08653966800000001,0.020811216,0.125519941,-0.051187616,-0.123615936,1.239348798,2.5122110980000003,,,,,,,,,-1457.8814231525175 -113,113,K30A,0.098663776,0.0018760839999999999,0.021097675,0.007989488000000001,0.0005815680000000001,-0.111935875,0.108051275,0.08927627699999999,0.125844321,0.009095029000000001,-0.005342861,-0.054948823,0.09714417199999999,-0.031863578,0.047842554,0.026443097999999998,-0.025279963,1.215440898,2.643618685,0.8379057790000001,0.6285286179999999,1.042039902,1.4987585069999998,-0.29369117,1.3138930359999998,0.9132755140000001,0.075666693,-1460.7623754139058 -114,114,K30C,0.033087663999999996,-0.010271905999999999,-0.019295232,-0.00294336,-1.5803495419999998,-0.046436457,0.074102922,-0.007927595,0.150253112,0.040484572999999996,-0.061028385,-0.03066882,-0.007921644,0.009360302,-0.015247021999999999,-1.3015970829999999,-1.859102,0.854706944,1.348014256,-5.779736073,-5.479257507000001,-4.939407799,-6.313172951,-6.8109703370000005,-5.3558717730000005,-6.583297117000001,-8.337572182999999,-1463.5151241258718 -115,115,K30E,0.0074243569999999995,-0.015315282,-0.036557396,-0.330340993,-1.653192955,-0.136973904,0.0111703,0.003678414,0.019338955,0.007837029,-0.038467593,-0.092635858,0.019521066,-0.16987803199999998,-0.49080395299999996,-1.450872194,-1.855513715,1.2269179829999999,1.389399291,-0.8223457959999999,-1.6970779569999999,-0.7433230820000001,-0.380125427,-1.323093552,0.031891037000000004,-1.271839753,0.317896481,-1463.0591673990712 -116,116,K30D,0.008336566,-0.03788243,-0.022883766,-1.3174528620000001,-2.1672425140000002,-0.121515065,0.014474141999999999,0.00219899,0.104033535,-0.015772561,-0.059992299000000006,-0.09842060400000001,0.052653072999999995,-0.766639906,-1.868265817,-2.384056039,-1.9504289890000002,1.7761049830000002,1.2814501329999999,-2.418209932,-3.253353249,-2.096512154,-2.774565056,-2.335383934,-1.6312352680000002,-1.999629703,-0.90221522,-1462.6670391550288 -117,117,K30G,0.033980705,-0.004905307,0.010699258,-0.8122872170000001,-2.15303464,-0.101360972,0.054263426,0.013697984,0.115023105,0.025310383,-0.035120997,-0.070186779,0.091585294,-0.461051681,-1.163522753,-2.047418377,-2.258650902,1.626647493,1.365891776,-3.1940967089999996,-3.447734337,-2.414639771,-3.092382713,-4.168910072,-2.84681665,-2.244031052,-2.46368263,-1464.487353454344 -118,118,K30F,0.027638142,0.008010398,0.000119235,-0.014441951000000001,-2.087469761,-0.186184963,0.009736959,0.045539325,0.098707741,0.019713267,-0.003692472,-0.089997059,0.09023552800000001,-0.081700587,0.052816685,-2.374815382,-1.80012414,0.7992767409999999,1.255140555,-6.344206351,-6.175813385,-4.970588928,-8.025809296,-7.446648804,-5.102171341,-5.849842117000001,-6.4117066760000005,-1469.9762594788335 -119,119,K30I,0.010255164,-0.091325398,-0.035397017,-0.043075065999999995,-0.404046646,-0.103629511,0.02578875,-0.005278422,-0.0012952060000000001,0.010289788000000001,-0.192940584,-0.026168319,-0.044625715,-0.005221698,-0.08092843400000001,-0.154915453,-0.653177838,1.4097763380000001,2.211424761,-4.334541829,-4.509805832,-3.477678177,-4.5217821119999995,-5.02389769,-4.139545334,-5.178339887,-5.233728922,-1466.9372705374844 -120,120,K30H,0.068215426,0.009651037,-0.017634302,0.011489618,-0.8669305959999999,-0.12539362199999998,0.10389050699999999,0.032540345,0.14324593800000002,-0.002925575,0.022227649,-0.09891257,0.063643967,-0.040180572000000005,0.063159808,-0.612208157,-1.121653035,1.173167464,1.5704268469999998,-3.7194872739999996,-4.27606691,-2.605091286,-4.27651622,-4.635035751,-2.8047262039999996,-2.424629756,-2.585755571,-1466.1077254009433 -121,121,K30M,0.062277793,0.023867304,0.059620796,0.034297133,-0.205193373,-0.167566206,0.077750317,0.046805268,0.053903535,0.11447330300000001,-0.066738695,0.031657772,0.08758382,0.030775956,0.037818309,-0.149276376,-0.26111037,1.159116453,2.0422286990000003,-3.2414203839999995,-3.616566727,-3.0954159160000003,-3.1765680080000003,-4.014547333,-2.304003937,-3.053468105,-3.7377399760000003,-1466.6047282465734 -122,122,K30L,0.060868552,-0.002755927,0.012091929,0.00917773,-0.30245332199999997,-0.163733151,0.070470193,0.051266911,0.097357835,0.020039192,-0.025551045,-0.032931954,0.057115810999999996,-0.037604623999999996,0.055960083,-0.24121340800000002,-0.36369323600000003,1.546319059,2.119093586,-4.155451071,-4.41808667,-3.955308891,-4.298294556,-4.726511543,-3.379053696,-3.872068358,-4.281316547,-1465.8869325630367 -123,123,K30N,0.05454254099999999,-0.007118245,-0.039191698999999997,-0.060147347000000004,-1.532004423,-0.205663956,0.06252315,0.046561932,0.104398949,-0.042242685999999995,0.028006196,-0.176746939,0.098363542,-0.091904051,-0.028390642999999997,-1.789549186,-1.27445966,0.844026608,1.313565448,-2.32740654,-2.536827377,-1.41341291,-2.6835651019999998,-2.672767746,-2.330459564,-2.328610533,-1.929901572,-1464.2221293542534 -124,124,K30Q,0.056873917,-0.002156619,0.029907995,0.04242421,-0.09384767699999999,-0.025276082000000002,0.062291927000000004,0.051455907,0.057852549,-0.00023532599999999998,-0.004077912,-0.047559457,0.107375447,-0.046455275,0.131303694,-0.11068791300000001,-0.07700744,1.5520766000000001,2.43852726,-0.281667992,-0.7865430529999999,0.22441309399999998,-0.19232415,-1.033077347,0.37919149799999996,-0.059245162000000004,0.187540596,-1463.3408974669874 -125,125,K30P,0.056774197,0.011558656,-0.6451668779999999,-2.126830294,-2.525360861,-0.126639626,0.08505597599999999,0.028492417000000003,0.093745909,-0.00623241,0.029349722,-0.492631505,-0.79770225,-1.938340705,-2.315319882,-2.260975792,-2.78974593,1.632231149,0.752570757,-2.89878623,-2.0823772430000003,-2.280247513,-3.102823738,-3.8812715910000004,-3.1472110669999998,-2.5164580930000002,-2.953931396,-1461.843950286042 -126,126,K30S,0.046516324000000005,0.021456691,0.00890171,0.0068549430000000005,-0.37863247200000005,-0.10435102199999999,0.060770968,0.032261679,0.128239908,0.072688719,-0.029775338,-0.043260302,0.061063722,-0.013390882,0.027100767999999997,-0.29357325300000003,-0.46369169,1.031033586,1.706710806,-0.555635321,-0.202871422,-0.09264872,-0.480241135,-1.748080048,-0.254335281,-0.942116066,-1.11555736,-1464.128975982312 -127,127,K30R,0.03564085,0.018416099,0.02329738,0.004958871,-0.006089577,-0.101736269,0.05223952,0.019042179,0.10084288599999999,0.037430635,-0.0005984380000000001,-0.019590623999999997,0.066185383,-0.012652426999999999,0.022570167999999998,0.038253262999999996,-0.050432417,1.261967274,2.8560040439999996,-0.398836171,-0.79846949,-0.070430267,-0.513058411,-1.214217468,0.601994781,-1.365970825,0.5873929489999999,-1461.0319403386675 -128,128,K30T,0.074175399,0.037650626,0.049637735999999995,0.029346545,-0.041735782,-0.024353211,0.12028411900000001,0.028066677999999998,0.10111700400000001,0.055799039,0.019502211999999998,-0.038494157,0.137769628,-0.0067375609999999996,0.06543065099999999,-0.058770113,-0.02470145,1.301148956,2.37562884,1.493426451,1.920127396,1.587223045,1.783307762,0.349395699,1.827078354,0.09739306699999999,-0.8518234,-1465.1783799417317 -129,129,K30W,0.050561882,-0.004388008,-0.015592951,-0.84836765,-2.032560763,-0.128216571,0.076736853,0.024386911,0.100389621,0.020688283000000002,-0.029464297999999996,-0.098291905,0.067106003,-0.44987580899999996,-1.24685949,-2.311228222,-1.753893304,1.608362532,1.320402571,-6.315228481,-6.152644569,-5.020183746,-7.288060196,-7.543967766000001,-5.571286125,-6.208597162999999,-6.843326166000001,-1466.8581158667803 -130,130,K30V,0.062050953,-0.029194402,-0.006741151,-0.009877641,-0.06138358,-0.096197487,0.08709329099999999,0.037008615,0.11495897599999999,0.0048822579999999996,-0.063271062,-0.053612636,0.040130334,-0.031999633,0.012244352,-0.011318385,-0.111448775,1.238995107,2.553759515,-3.035197964,-3.4481820830000003,-2.42438118,-2.959265999,-3.792495995,-2.551664566,-3.504808273,-3.835945057,-1466.9526129821315 -131,131,K30Y,-0.032652425,-0.07024907700000001,-0.064128776,-0.10163177400000001,-2.123162699,-0.225698808,-0.01108261,-0.05422224,0.071096854,-0.03064554,-0.109852614,-0.101457641,-0.02679991,-0.096910013,-0.106353534,-1.718086295,-2.5282391019999997,0.63880243,1.3077506909999999,-5.676549431000001,-5.240430244,-4.175158318,-7.222781235,-6.810007614,-4.934369743,-4.597604732,-4.786747119,-1470.024944262579 -132,132,V31A,-0.075996644,-0.02437406,0.000986701,-0.032705785,-1.100230314,-0.007892398,-0.08607370800000001,-0.06591958,-0.013371738999999999,-0.059693578,0.010945458,-0.015030922,0.017004323999999998,-0.043814634000000005,-0.021596935,-0.7125761490000001,-1.487884479,0.7724076590000001,1.4086576380000002,-2.5629998869999997,-2.539596916,-2.873806938,-1.16427105,-2.694993637,-3.5423308939999996,-3.0295278239999996,-2.046100846,-1465.5938697583042 -133,133,V31C,-0.065796181,-0.054665922,-0.03560006,-0.080138818,-0.095361794,0.042011734,-0.112345395,-0.019246966,0.024096819,-0.06275637099999999,-0.046575472,-0.070579737,-0.0006203830000000001,-0.083053664,-0.077223972,-0.06745872,-0.12326486699999999,1.293950139,2.2597102419999997,-7.620479198,-7.680981247,-7.131140785,-6.71985659,-8.352412467999999,-8.218004898,-4.860159266,-3.947978623,-1465.3072666339576 -134,134,V31E,-0.048830646,-0.989157572,-2.3650674130000002,-3.050932108,-2.9764645589999996,-0.032285376,-0.014184621000000001,-0.08347667,0.08383328599999999,-0.677285147,-1.301029996,-2.461660864,-2.268473962,-2.873635008,-3.228229208,-2.672047362,-3.280881755,0.19891587800000002,-0.562142554,-9.085897371,-9.482632393,-9.161206879,-8.324126488,-9.184479668,-9.277041427999999,-8.241014407,-8.525554921,-1468.9017770527862 -135,135,V31D,0.032329615,-0.71383255,-1.948469096,-2.322709146,-3.1479118710000003,0.009214029,0.074801808,-0.010142578000000001,-0.03480903,-0.553759007,-0.873906093,-2.1276745630000002,-1.7692636290000001,-2.3635574480000003,-2.281860844,-3.1162123110000004,-3.179611431,1.109715007,-0.284615183,-9.560686906,-10.10386174,-9.511571793,-9.017572029,-9.527042084,-9.643386887,-8.241014407,-8.525554921,-1471.6696903994307 -136,136,V31G,-0.062077347000000005,-0.01700883,-0.964319232,-2.284034961,-3.019922186,0.031486572000000004,-0.04441844,-0.07973625299999999,-0.034541572,-0.039048788,0.0050311290000000005,-0.632927667,-1.2957107970000001,-2.20009978,-2.367970141,-2.972958029,-3.066886342,1.643490778,0.647165082,-8.657687073,-9.237576248,-8.62345874,-7.8483445970000005,-8.704456032000001,-8.874599747000001,-8.241014407,-8.525554921,-1467.435330949258 -137,137,V31F,-0.044471795,-0.039700708,-0.56179174,-1.806706091,-2.8994654160000004,-0.051352928,-0.039598546,-0.049345044000000005,-0.071258394,-0.045363463,-0.034037952,-0.361957951,-0.7616255279999999,-1.773932094,-1.8394800869999999,-3.003708212,-2.79522262,1.526848631,0.7729338509999999,-7.436471581,-7.018656029,-7.112294006,-6.463050132999999,-8.95459169,-7.633766045,-3.870201435,0.400074225,-1460.2905115052126 -138,138,V31I,0.044659067000000004,0.00942231,0.036875603,-0.019516789,-0.051860533,-0.06270679400000001,0.045303247000000005,0.044014885999999996,0.027440762,0.023777846000000002,-0.004933226,-0.020128488,0.093879694,-0.023977696,-0.015055882,-0.044985101,-0.058735965,1.2133435590000001,2.3989563869999997,-0.435060857,-0.123762497,-0.969246185,-0.8097898179999999,-0.50168174,0.22917595699999999,-1.5164643230000001,1.2162439170000001,-1459.086202097591 -139,139,V31H,-0.103879166,-0.362949439,-2.058749347,-2.273232696,-3.3994654160000004,-0.025588131,-0.09409655199999999,-0.113661779,0.07860602400000001,-0.21155801300000002,-0.514340865,-2.2192904469999997,-1.898208246,-2.18410656,-2.362358832,-3.3047382080000003,-3.4941926239999996,0.300205071,-0.386077794,-11.02338548,-10.33589017,-11.29593047,-10.20894553,-11.56431229,-11.71184893,-8.241014407,-8.525554921,-1466.0330000091344 -140,140,V31K,-0.069959217,-1.025541657,-2.282289191,-2.2384576419999997,-2.791626345,-0.015471355,-0.056984189000000005,-0.082934244,0.020253137,-0.701422558,-1.349660755,-2.7297345539999998,-1.8348438269999998,-2.238618711,-2.238296573,-2.639091056,-2.9441616330000002,0.380747902,-0.558198513,-9.626291118,-10.31131435,-9.45243634,-8.79461573,-9.529177353,-10.04391182,-8.241014407,-8.525554921,-1463.7878213031217 -141,141,V31M,-0.041561627999999996,-0.007445106,-0.019076704,-0.002869713,-1.5532654280000002,-0.044758175,-0.077024889,-0.006098366,-0.080091179,-0.038053519,0.023163307999999997,-0.041572092000000005,0.0034186840000000004,-0.021768302000000003,0.016028877,-1.3509075469999998,-1.755623308,0.803002848,1.339782133,-4.757160342,-4.471318558,-4.5173685610000005,-4.742915482,-5.079248596,-4.974950516,-3.298961354,-1.560200634,-1462.3380164215341 -142,142,V31L,-0.031101205,-0.036818767999999995,-0.00173694,-0.031376676,-0.08842578699999999,-0.048389108,-0.053680381,-0.008522028000000001,0.013463985,-0.027364741,-0.046272794000000006,-0.024077422,0.020603543000000002,-0.033727436,-0.029025915,-0.060220939,-0.116630635,1.240399902,2.312975351,-2.326860617,-2.352951843,-1.005902313,-2.903250206,-2.9603717960000004,-2.411826927,-1.8583076840000001,1.443182849,-1459.5768478424288 -143,143,V31N,-0.07502806599999999,-0.024041029,-1.09737067,-2.345433129,-2.8590112089999997,-0.045339542000000004,-0.094956601,-0.05509953,0.016846616000000002,-0.051617024000000004,0.0035349659999999996,-0.794723453,-1.4000178859999999,-2.437146518,-2.25371974,-2.888771385,-2.8292510319999997,1.097612071,0.25527794600000003,-9.883094162,-10.60920161,-10.56843042,-9.054346039,-9.737616142,-9.445876595,-8.241014407,-8.525554921,-1467.8106265091337 -144,144,V31Q,-0.059804750999999996,-0.6256500079999999,-2.061013374,-2.629836465,-3.0069139089999997,0.027160731,-0.055417799000000004,-0.064191702,0.033721492,-0.47798520299999997,-0.7733148120000001,-2.194363841,-1.927662906,-2.305307988,-2.9543649419999998,-2.7057803330000003,-3.308047484,0.487568376,-0.459309165,-9.394928345,-10.14651067,-9.274348022,-8.670092072000001,-9.271468185,-9.612222771,-8.241014407,-8.525554921,-1470.123696751427 -145,145,V31P,-0.042273958,-0.751933821,-1.770383745,-2.196451302,-3.1373510610000004,-0.044176823,-0.0223778,-0.062170116,0.022724203999999998,-0.5592656810000001,-0.94460196,-1.8044630069999998,-1.736304482,-1.973399102,-2.419503502,-2.7418482319999997,-3.5328538889999996,3.117013314,1.265685669,-8.989638065,-9.740840667999999,-8.963133873,-8.168106186000001,-9.034269843999999,-9.041839752000001,-8.241014407,-8.525554921,-1468.4229245414026 -146,146,V31S,-0.047669584,-0.008726814,-0.120025718,-1.666378845,-2.725262278,-0.046619187,-0.045684265999999994,-0.049654902,-0.034127557999999995,-0.054309917,0.03685629,-0.09015321,-0.149898225,-1.30093041,-2.0318272790000003,-2.462954743,-2.987569813,1.084960804,0.771125865,-7.989450751000001,-8.354382401,-8.490204788,-6.9095855639999995,-8.006886345,-8.186194656,-7.817359495,-6.92075765,-1468.499865962658 -147,147,V31R,-0.05958056900000001,-0.717611195,-1.875773689,-2.483971873,-3.1480649510000003,-0.008960364,-0.050560348,-0.06860078900000001,0.029255400000000004,-0.507528423,-0.927693966,-1.946623155,-1.8049242230000002,-2.160229645,-2.807714101,-3.0097945210000003,-3.28633538,1.4063231180000002,-0.058265894000000006,-9.708960872,-10.47475101,-9.511413002000001,-9.10216449,-9.478334061,-9.978141800000001,-8.241014407,-8.525554921,-1464.932245684322 -148,148,V31T,-0.045244165999999995,-0.0076924509999999995,0.002721587,-0.049525107,-1.944226231,-0.018735602,-0.036194725,-0.054293607,-0.026824569,-0.016471562,0.00108666,-0.019593700000000002,0.025036872999999998,-0.061203932999999995,-0.03784628,-1.882740085,-2.005712376,0.918187608,1.311526999,-6.2356979489999995,-6.894956497000001,-6.409180824,-5.043300819,-5.959005341,-6.872046265,-6.235958592,-4.671766847,-1466.5297726034187 -149,149,V31W,-0.02646088,-0.02298481,-0.9213366009999999,-2.366458266,-2.890630995,-0.020001108,-0.01724748,-0.035674278999999996,-0.037005403,-0.007281058000000001,-0.038688562,-0.615422444,-1.227250757,-2.369819268,-2.3630972630000002,-2.821444136,-2.9598178539999997,1.1038843170000001,0.327111541,-9.187465666,-8.899790344,-8.154858109,-8.157319115,-10.84349556,-9.881865204,-4.838212225,-3.17142041,-1460.0940309395082 -150,150,V31Y,-0.104011732,-0.8204163390000001,-2.4710410659999997,-2.7053607680000002,-2.670483841,-0.045836410999999994,-0.08707727900000001,-0.120946185,-0.027037858999999997,-0.5163391420000001,-1.124493535,-2.373023377,-2.569058755,-2.784997521,-2.625724015,-2.7595011339999997,-2.5814665480000003,0.418124624,-0.487804811,-11.43196246,-10.05513752,-12.14379382,-10.38564597,-12.370989100000001,-12.20424586,-5.306024198999999,-3.8115719269999997,-1462.5771539332345 -151,151,K32A,-0.015604663999999999,0.019891445,0.0078084090000000005,0.008947247,0.054800478,-0.002158839,-0.012115308,-0.019094019,-0.007887097,0.073827632,-0.034044742999999995,0.00126584,0.014350978,0.008419326,0.009475167,0.073109985,0.03649097,1.0628804440000001,2.728188479,-1.3216939559999998,-2.873778427,-0.325176743,-3.460142937,0.602401222,-0.551772896,-3.683966882,1.152396283,-1454.3597962288186 -152,152,K32C,-0.039695645,-0.027003285,-0.021839165,-0.000174733,-0.969015678,-0.01477086,-0.042939199000000004,-0.036452091,0.021777464,0.06820574,-0.12221231,-0.026254053,-0.017424276000000002,-0.025397414,0.025047947999999997,-0.66856635,-1.269465005,0.840692518,1.438080262,-6.083610005,-7.131878113,-5.697205795,-8.132425162999999,-4.466801422,-4.989739532,-6.369513465,-4.008096216,-1453.2993523124605 -153,153,K32E,-0.066786435,0.011041277,-0.017254346,0.00038264699999999996,-0.144527081,0.022663684,-0.095066284,-0.038506585,0.03718057,0.07807411,-0.055991556,0.04693887,-0.081447561,3.7e-05,0.0007282930000000001,-0.056360560999999997,-0.23269360000000003,1.334963185,2.5473945540000003,-1.336587537,-1.480103409,-0.919144981,-2.0954459990000003,-0.887650673,-1.3005926209999998,-2.066542786,0.471515256,-1454.250815439038 -154,154,K32D,-0.080591094,-0.022217112999999997,-0.023182696000000003,-0.07894704799999999,-2.3348927059999998,0.023070007000000003,-0.07809347,-0.08308871799999999,-0.036603018,0.044819952,-0.089254178,-0.12653599699999998,0.08017060599999999,-0.073379107,-0.08451498800000001,-1.8553533969999998,-2.814432014,0.941837523,1.3153314440000001,-2.756284123,-2.7517472919999997,-2.296906914,-4.092553085,-1.976085457,-2.664127869,-3.786602979,-0.461252834,-1456.8770111924969 -155,155,K32G,-0.068605018,-0.000238825,-0.015770798,0.004542492,-0.282379712,0.0049781159999999994,-0.091306135,-0.0459039,-0.045278386,0.087542021,-0.088019671,0.015913418000000002,-0.047455013,0.027912556,-0.018827573,-0.225527198,-0.339232225,1.059827846,1.810152875,-3.628366774,-4.454512512,-3.05998925,-5.580658829,-2.302362785,-2.744310493,-3.476903979,-1.3381001959999999,-1458.560704806354 -156,156,K32F,-0.034970701,0.069830428,0.002291099,0.047763703,-0.594552833,0.040633457000000005,-0.040622757,-0.029318643999999998,0.010545084,0.128267214,0.011393641000000001,-0.011360806999999999,0.015943005,0.061628345,0.033899061,-0.464260915,-0.72484475,0.5322882529999999,1.408297057,-5.196635941,-5.838807655,-4.962921188,-6.945696899,-3.52518586,-4.7105681,-5.25442034,-2.765570382,-1445.7535011265427 -157,157,K32I,-0.053923187000000004,-0.006977377,0.014303943000000001,-0.00935546,-0.017447561,0.002433742,-0.073641634,-0.034204739,-0.07640196,0.076829591,-0.090784344,-0.023575119,0.052183005,0.046972401,-0.065683321,-0.01458913,-0.020305992,1.244701655,2.497998054,-3.6626840589999996,-4.460034546,-3.2915893019999998,-5.295749451,-2.232616852,-3.033430145,-3.898592622,-2.253665501,-1445.073091017548 -158,158,K32H,-0.052013552000000005,0.009416246,-0.016035267,0.008534208,0.006558769,0.008257579000000001,-0.066639252,-0.037387851,-0.067018725,0.11406514,-0.095232649,0.009189445,-0.041259979,0.06273718,-0.045668765,0.04258707900000001,-0.029469541000000002,1.301710207,3.17062907,-3.398539857,-3.5123823780000003,-3.069107025,-4.121965744,-2.393845512,-3.895398628,-4.24838776,-1.83329151,-1459.6920552910306 -159,159,K32M,0.015388873999999999,0.06540062099999999,0.003718816,0.023057327000000002,-0.0038691000000000003,0.008279769000000001,0.00998322,0.020794528,0.041552822999999996,0.104038559,0.026762682000000003,-0.014190238999999999,0.021627871,0.036970492,0.009144161,-0.027968929,0.020230729,1.213061959,2.521449409,-4.37464368,-5.088653,-4.376490677,-6.1072882,-2.676566788,-3.624219734,-4.874484142,-2.792572305,-1449.2263530083 -160,160,K32L,-0.048355687,-0.007040698000000001,-0.009700128,-0.001780173,-0.075988297,0.024515292,-0.054544410999999994,-0.042166962999999995,-0.006754505,0.046311446,-0.060392840999999996,-0.038804322999999995,0.019404067,-0.015385393999999998,0.011825048999999999,-0.062223224,-0.089753369,1.521587861,2.602421961,-3.9215794739999996,-4.823204071,-3.89752195,-5.799933281,-2.018369194,-3.0688688739999996,-4.659920044,-1.885810279,-1442.8688697698526 -161,161,K32N,-0.065733575,0.006450168,0.0077322630000000005,-0.015648105,-0.19436535300000002,-0.024103531,-0.085297005,-0.046170144,-0.145618789,0.04848105900000001,-0.035580723,-0.029665632999999997,0.045130159,0.003637182,-0.034933392,-0.221200039,-0.167530667,1.436897644,2.132181688,-2.976704341,-2.984287933,-2.06628096,-4.9645049210000005,-2.252551514,-2.615896378,-4.431956099,-0.9283791659999999,-1459.6208524932154 -162,162,K32Q,-0.010354301,0.092674519,0.043778557,0.0034815320000000003,0.122206575,0.012338793,-0.018077528,-0.002631073,-0.061379087,0.15707363900000001,0.028275399,0.046556586,0.041000527,0.059868973,-0.05290591,0.15267144300000002,0.09174170699999999,1.053747927,2.964747425,-0.619891478,-0.156779282,-0.599383553,-0.8340753479999999,-0.604265289,-0.904953918,-1.755941358,0.090153151,-1458.4318764456548 -163,163,K32P,-0.028991613,-0.351435392,-1.809724675,-2.19368559,-2.976554563,0.001891771,-0.024130227,-0.033852999,-0.035815658,-0.086091454,-0.616779329,-1.741367005,-1.878082345,-2.124869383,-2.262501796,-2.527585878,-3.425523248,0.6933068259999999,-0.028133734,-6.657078404,-7.7328633270000005,-6.031923247999999,-8.566618767000001,-4.817249985,-6.136736694,-6.129094091,-4.504052758,-1457.7928214138374 -164,164,K32S,-0.033017345,-0.018210197,-0.024197017999999997,-0.008787721,-0.17798450100000002,-0.025022237000000003,-0.053070999,-0.01296369,0.005381998000000001,0.044375092000000005,-0.080795485,-0.041040235,-0.007353801,0.0013994160000000001,-0.018974858,-0.154427826,-0.201541175,1.502444811,2.281921444,-2.1162538669999997,-2.8248339839999996,-1.070628044,-4.806527718,-0.3950298,-1.484249786,-3.140940173,-0.38099838700000005,-1458.0501389289275 -165,165,K32R,-0.031927773,-0.007760311,-0.006062351,-0.017886342,0.068602495,-0.0034593009999999997,-0.046083975,-0.017771571,-0.074888896,0.073190418,-0.08871104,-0.016200362,0.0040756609999999995,0.000206862,-0.035979545,0.08448789599999999,0.052717093,1.065808838,2.7758931689999997,-0.591184605,-0.718717857,-0.752425873,-0.440273972,0.041881699,-1.086387024,-1.8391972769999998,0.57278973,-1459.2206598855555 -166,166,K32T,0.0051539509999999995,0.043806982,0.009874979,0.023930992,-0.146127025,0.012004618,0.012910033999999999,-0.002602132,-0.089879385,0.08644841800000001,0.001165545,-0.003040686,0.022790644,0.032783392,0.015078591,-0.11620750699999999,-0.176046543,1.366388695,2.31651611,-2.524708043,-3.243774834,-1.709476906,-5.142050323,-0.879074562,-1.649163589,-2.791133663,-0.635363317,-1455.496642215643 -167,167,K32W,-0.11583792300000001,-0.000877116,0.03673846,0.024794748999999998,-0.24052084899999998,0.021712977,-0.06475629,-0.166919555,-0.092079997,0.085441653,-0.087195884,0.088385683,-0.014908763,0.105930876,-0.056341378,-0.15508158800000002,-0.32596011,1.139721197,2.093516731,-7.769459604,-8.513265221000001,-7.538756424,-9.038483429,-6.401240295,-7.35555265,-8.401911781,-7.454458271,-1449.6428314461373 -168,168,K32V,-0.004279184,0.030147444,-0.011977426000000001,-0.005510322,-0.073791384,-0.024232961,-0.017410486,0.008852118,-0.040961781,0.084598887,-0.024303999,-0.026975887999999996,0.003021036,0.003405258,-0.014425901999999999,-0.035733414,-0.111849354,1.231212902,2.4636774359999998,-3.437167526,-4.452638763,-3.113702515,-5.106428062,-1.66657811,-2.846490181,-3.9295804530000003,-1.68344417,-1448.322954078205 -169,169,K32Y,-0.030621018,0.01379667,0.026521195,0.016163333999999998,-0.35842172,0.003269877,-0.014282456,-0.04695958,-0.000681246,0.087826791,-0.06023345099999999,-0.011059388,0.064101778,0.014659253999999998,0.017667414,-0.237644813,-0.47919862700000004,1.632950097,2.26484178,-5.756456578,-6.089122345,-5.542023712000001,-7.307602081000001,-4.295888893,-5.547645859,-5.698332763,-3.381149621,-1448.8879405814223 -170,170,D33A,0.028067865,-0.04812054,-0.022572997999999997,-0.040386565,-0.0056255459999999995,0.008648798000000001,-0.016807806,0.072943535,-0.096200525,-0.12281275900000001,0.026571678999999997,-0.08438582,0.039239825,-0.050254634000000006,-0.030518496000000003,-0.008656961999999999,-0.00259413,1.070070397,2.4977076019999997,0.80247679,0.328408989,1.05194574,0.8419365390000001,0.757934311,1.032158371,-0.9246621690000001,1.147866771,-1465.0823424602859 -171,171,D33C,0.008000925,-0.085715771,-0.040377672,-0.08298181,-0.143159049,0.046908974000000006,-0.02011385,0.0361157,-0.076739729,-0.11634310099999999,-0.055088440999999995,-0.066729522,-0.014025822,-0.059129575,-0.106834044,-0.103644393,-0.182673705,1.3428698609999998,2.2604550519999997,-5.647521811,-5.762804611,-5.125831451,-6.190252335,-5.782899841,-5.375820816,-6.730293744,-7.812815001000001,-1462.485833177343 -172,172,D33E,-0.030137327000000002,-0.079703765,-0.004627208,-0.06942323,-0.038181221,0.002398536,-0.039935291,-0.020339363,-0.055894417,-0.09693776400000001,-0.062469765999999996,-0.020479725,0.011225309,-0.10286251699999999,-0.035983943,-0.022735049,-0.053627392999999995,1.14559757,2.243716485,0.9121137909999999,0.39334818299999996,0.814259315,0.965996552,1.211355804,1.1756091,0.168026208,0.749457736,-1460.784847419709 -173,173,D33G,-0.033577052999999996,-0.12307061300000001,-0.056711856,-0.070387108,-0.164200601,-0.039234579,-0.083108335,0.015954229,-0.06866243400000001,-0.13273454,-0.11340668599999999,-0.088232638,-0.025191072999999998,-0.049863522,-0.090910693,-0.130331409,-0.198069792,1.503541187,2.317370164,-1.195077411,-0.7135766370000001,-0.9890693509999999,-1.489844879,-1.312773933,-1.4701222530000002,-1.849383724,-0.8085067359999999,-1466.736363586504 -174,174,D33F,0.008737043,-0.014125427,-0.002050294,-0.065057898,-0.24443278300000001,-0.072733668,-0.036603408999999996,0.054077494000000004,-0.036864066,-0.080025947,0.051775094,-0.059205725,0.055105138,-0.029565896,-0.1005499,-0.22466540899999998,-0.264200156,1.590887955,2.182387887,-4.399182268000001,-4.395158623,-4.629882545,-4.269723618,-4.389423401,-4.311723152,-4.83881443,-3.900884128,-1463.9928375547752 -175,175,D33I,-0.003618043,-0.055324998,-0.045078097000000004,-0.041143382,-0.137432674,-0.081726703,-0.020178281,0.012942195,-0.024797579,-0.080330471,-0.030319525,-0.04826706,-0.041889132999999995,-0.007796949,-0.074489814,-0.08045174299999999,-0.194413604,1.568759957,2.584738296,-2.5700394490000003,-2.824345741,-2.016215172,-2.479498581,-2.770048676,-2.760089073,-3.5929299230000002,-2.720193299,-1463.08049129555 -176,176,D33H,0.018694363000000002,-0.03809453,-0.00484842,-0.046429917,-0.043367243,0.0024591120000000003,-0.027099971,0.064488696,0.005070412,-0.098402151,0.022213092,-0.049485363,0.039788523,-0.05421804,-0.038641794,-0.068558274,-0.018176211,1.467867817,2.449785519,-2.114678854,-1.7144647519999998,-2.737026985,-2.686160736,-1.7428557130000002,-1.692886086,-2.452988378,-1.822084611,-1462.5016216742806 -177,177,D33K,-0.017405218,-0.086614501,-0.054365791,-0.080006361,-0.046872657000000005,0.01170058,-0.051793864,0.016983428999999998,-0.114247486,-0.208207014,0.034978012999999995,-0.162018852,0.05328727,-0.044059945999999996,-0.115952776,-0.05282474,-0.040920572999999995,1.298172133,2.38351553,-0.014223093000000001,0.20845569600000002,-0.24383673100000003,-0.09459121699999999,0.43496434,-0.376107552,-0.965441355,-0.052188227999999996,-1459.1737822545692 -178,178,D33M,0.020699022,-0.060268599000000006,0.001867865,-0.047416055,-0.057818308,-0.012184759,-0.005470991999999999,0.046869035,-0.096813256,-0.12350587,0.0029686720000000003,-0.029353703999999998,0.033089433,-0.040610545,-0.05422156400000001,-0.026203677999999998,-0.089432938,1.242270519,2.479057567,-2.597623955,-2.939754272,-2.2825149380000003,-2.713197884,-2.6000198969999997,-2.452632782,-3.3876831239999996,-3.215082232,-1463.7173624518327 -179,179,D33L,0.017343449,-0.051276325,-0.015540176999999999,-0.041125645,-0.12325609400000001,-0.077431365,-0.027761312000000003,0.062448209000000005,-0.055784044000000005,-0.093151724,-0.009400925,-0.028822359,-0.002257994,-0.021069002000000003,-0.061182288,-0.112721032,-0.133791155,1.244755435,2.145553241,-1.289866704,-1.9227475809999999,-0.674990669,-1.326394676,-1.465317116,-1.059883476,-1.6973104980000002,-2.211875867,-1463.7244687355123 -180,180,D33N,-0.037355486,-0.118014366,-0.06751529099999999,-0.072507328,-0.11224645300000001,-0.061005645,-0.079784918,0.005073946,-0.039393628,-0.189686372,-0.04634235900000001,-0.07651685400000001,-0.058513727,-0.077954575,-0.067060081,-0.10110668699999999,-0.123386219,1.529141047,2.441341006,-1.3271630490000002,-1.201438576,-0.6502388920000001,-2.294653351,-1.295632889,-1.19385154,-1.952631617,-1.012338527,-1462.147893756628 -181,181,D33Q,0.007322337,0.055390603,0.074061349,-0.016990856000000002,0.091680231,0.039116912000000004,-0.024839626,0.039484299,-0.146520361,-0.08689137400000001,0.19767258,0.063983096,0.084139601,0.021165611,-0.055147322,0.061061726,0.122298735,1.114191852,2.7964486280000003,1.026545825,0.889540604,0.77407663,0.5029770889999999,1.11729982,1.848834984,0.272078556,0.317271609,-1464.0884348265827 -182,182,D33P,-0.021065625,-0.802559472,-1.926844426,-2.416858057,-2.895012627,-0.015120976000000001,-0.023574382,-0.018556868,-0.005551098000000001,-0.584493614,-1.02062533,-2.013365571,-1.84032328,-2.422145831,-2.411570283,-2.397732773,-3.392292481,1.439836923,-0.109452601,-3.7395363010000002,-2.787286354,-4.315875221000001,-4.836216408,-4.216392517,-2.541911003,-3.8689113980000003,-2.029706323,-1465.4871195526794 -183,183,D33S,0.032601639,-0.037366995,-0.038649426,-0.038795675,-0.055098192000000004,-0.009941255,-0.00042185,0.065625128,-0.068625717,-0.098808423,0.024074433,-0.08732652,0.010027669,-0.041447124,-0.036144225,-0.070404881,-0.039791503,1.346617838,2.392328891,-0.10474197199999999,-0.345059525,0.861704742,-0.49730036200000005,-0.548603531,0.0055488130000000005,-1.64705669,-0.28764531600000004,-1463.5055706431158 -184,184,D33R,-0.015938911,-0.096471692,-0.02063636,-0.060886155,-0.055448761,0.000517267,-0.044070165999999994,0.012192343999999999,-0.050759813,-0.10515092,-0.087792464,-0.051898535,0.010625816000000001,-0.036682286,-0.085090023,-0.0052160290000000005,-0.105681493,1.250163816,2.4872572490000002,-0.070885849,-0.075153809,-0.38326278700000005,-0.308354774,0.299405533,0.11293659199999999,-0.13290026800000002,0.284242443,-1455.9826387991197 -185,185,D33T,0.004202834,-0.038370529,-0.023354019,-0.055334612000000005,0.00270366,-0.017381901,-0.034163901,0.042569567999999995,-0.045460062,-0.086442097,0.00970104,-0.015408197,-0.03129984,-0.026593647,-0.084075576,0.00210796,0.00329936,1.266983826,2.5937999080000003,-0.505052081,-0.942996872,0.141645103,-1.081496567,-0.835024345,0.19261227399999997,-1.063348698,-0.6656722279999999,-1463.8241920229048 -186,186,D33W,0.030054375,-0.095488369,-0.06156313099999999,-0.06184637,-0.26217333,-0.089924785,-0.0044435609999999995,0.064552311,-0.204612899,-0.159113739,-0.031862998999999996,-0.126771517,0.003645255,-0.084082485,-0.039610255,-0.272505082,-0.251841578,1.608665191,2.153229267,-5.3816069760000005,-4.914779816,-5.428023735,-6.038625809,-5.518395729,-5.008209793,-5.618158526,-5.466240647999999,-1460.7749760476872 -187,187,D33V,-0.020273513,-0.08419586400000001,-0.034279172000000004,-0.073608704,-0.080936175,-0.024357951,-0.054246657999999996,0.013699632,-0.050629135,-0.093137604,-0.07525412299999999,-0.048094925999999996,-0.020463417,-0.012392344,-0.134825063,-0.056970928,-0.104901422,1.354164364,2.434191365,-2.342069954,-2.645092911,-2.120745178,-2.367964386,-2.277355248,-2.299192047,-3.318185598,-2.5717911680000003,-1465.2260714764707 -188,188,D33Y,-0.008606986,-0.08538158900000001,-0.010297231,-0.058198772999999995,-0.16099438900000002,-0.072827319,-0.060259567,0.043045595,-0.063958889,-0.12450133099999999,-0.046261845999999995,-0.039034242000000004,0.01843978,-0.029671107999999998,-0.086726438,-0.159242808,-0.162745969,1.448498494,2.2007590269999997,-4.627052341000001,-4.236046127,-5.501634796,-4.810698685,-4.362141617,-4.224740478999999,-4.6263427010000004,-3.815463189,-1462.828617111314 -189,189,A34C,-0.068932711,-0.034236007,-0.0064411369999999996,-0.034724992,-0.5213988970000001,-0.016597971,-0.07661884,-0.061246580999999994,-0.129251473,0.057239632,-0.12571164599999998,-0.014511363000000001,0.00162909,0.043383802,-0.112833785,-0.282587563,-0.760210231,0.822278583,1.613852689,-5.971443784,-5.804804459,-6.146641991,-6.23464447,-6.324600029,-5.346527968999999,-5.754721842,-2.762958867,-1467.1212028395385 -190,190,A34E,-0.0033855829999999997,0.033829253,-0.288512877,-1.7741873030000002,-2.556684305,0.152784916,0.068072765,-0.07484393,-0.074891286,-0.026620708,0.094279214,-0.127160245,-0.44986550799999997,-1.691999621,-1.8563749840000001,-2.37894574,-2.73442287,0.975032155,0.7074182309999999,-2.658605421,-1.346268784,-2.006614243,-4.087689255,-3.484255676,-2.36819915,-3.8940296,-0.61948546,-1461.2980675627477 -191,191,A34D,0.039054992999999996,-0.060048405,-1.300400217,-2.243853935,-2.404831914,-0.009712299999999998,0.070316675,0.00779331,0.033124746000000004,-0.016749552,-0.103347257,-1.094721462,-1.5060789719999998,-2.014748866,-2.472959003,-2.303754977,-2.50590885,2.680774685,1.269176658,-6.497422841000001,-5.734475174,-5.556617942999999,-7.568806015,-7.62168367,-6.005531402999999,-5.702284668,-2.703776642,-1464.8026282810606 -192,192,A34G,-0.027909528,-0.058421028,-0.020882787,0.003717636,-1.8612982530000002,0.056961999000000006,0.005028976,-0.060848031,-0.015885437,-0.03623098,-0.080611075,-0.037798817,-0.003966756,0.021835498,-0.014400226,-1.42788701,-2.294709495,0.698884994,1.32460961,-6.761407748,-6.723408401,-6.215696822999999,-7.54002906,-6.900638252,-6.427266205,-7.324677192999999,-5.597197711000001,-1466.256655480247 -193,193,A34F,0.037697192000000004,0.020944169,0.083382405,0.057913149000000004,-0.922138302,-0.11511673800000001,0.008864325,0.066530058,-0.032197439,0.009912086,0.031976251000000004,-0.01195624,0.17872105,0.00595922,0.109867078,-0.659327839,-1.184948765,0.989580751,1.486046889,-5.778544209,-6.526846657,-6.281155837999999,-6.1385877760000005,-6.269626037999999,-3.676504738,-4.0991273360000005,-1.13754861,-1464.9190559908748 -194,194,A34I,-0.042221993,-0.062442994,-0.000783128,-0.010175306,-0.548549981,-0.004862668,-0.072984902,-0.011459083,0.029771617,-0.027015576,-0.09787041099999999,-0.041245616,0.039679361,-0.0075952630000000005,-0.012755348,-0.40152299700000005,-0.695576965,1.4274644619999999,1.87887019,-2.182220406,-1.5295697019999999,-2.229482826,-3.3282700039999997,-2.0194830319999997,-1.804296463,-2.0512860219999998,1.6471717909999999,-1465.377818045672 -195,195,A34H,-0.003337041,-0.02819132,0.028280672000000003,-1.4922301919999998,-2.609230586,-0.0022504,0.013308898000000001,-0.01998298,-0.17627118600000002,-0.016610494,-0.039772146,0.005560821,0.051000522,-1.102792299,-1.881668085,-2.157715204,-3.060745967,2.206472218,1.462723899,-6.3864383060000005,-7.68664991,-6.508765228,-5.771848877,-7.172161995,-4.792765518,-5.44767231,-2.54575115,-1465.9953569318168 -196,196,A34K,-0.077572353,-0.048104207999999996,-0.06762512400000001,-1.7756094690000002,-2.635557452,0.057446671,-0.039264024,-0.115880682,0.09734742,-0.11588714800000001,0.019678733,-0.06571938599999999,-0.069530861,-1.441379129,-2.109839809,-2.730385239,-2.540729664,1.255795985,0.783212221,-6.063076887999999,-6.174085709,-5.438094688,-6.79254538,-6.598327621,-5.312331039,-5.5562968370000005,-2.40478857,-1464.4265471198596 -197,197,A34M,-0.019095921000000002,-0.032903227,0.06754402,0.033118193,0.003700525,0.09172502,-0.009891635,-0.028300206,0.059415267,-0.042361197,-0.023445256,0.025061093,0.110026946,-0.004921378,0.071157763,0.055454410999999995,-0.048053362,1.115892828,2.8013129310000005,-5.414141599,-5.639139267000001,-5.1905634769999995,-5.497856606,-6.040427658,-4.702720985,-3.615274518,-1.3898556430000002,-1468.1922577517107 -198,198,A34L,-0.023000883,-0.05464354900000001,0.005779463,-0.002092054,-0.88252558,0.036740237,-0.042813322,-0.0031884440000000003,-0.040629136,-0.037388634,-0.071898463,-0.032637327,0.044196253,0.002141139,-0.006325246,-0.631842141,-1.133209018,1.045491769,1.513181738,-2.9143413239999996,-3.222324448,-2.663490814,-2.665033012,-3.135467285,-2.88539106,-2.141117532,2.291497469,-1464.653520909138 -199,199,A34N,0.022826294,0.006889193,-0.364289176,-1.6651285,-2.37743765,-0.041997954000000004,0.034767024,0.010885563999999999,-0.00279023,-0.02831812,0.042096505,-0.28177247899999996,-0.44680587200000005,-1.4110131380000002,-1.919243861,-2.13367481,-2.621200489,2.394774782,1.485436099,-6.659808302,-6.87095829,-6.7060914689999995,-7.148018737999999,-7.024010399,-5.549962616,-6.0321157979999995,-3.6386020739999996,-1467.183264374733 -200,200,A34Q,0.008920508,0.04403544400000001,0.029474761000000002,0.048950552,-1.292157836,0.132280893,0.035596674,-0.017755659,-0.020197041000000002,0.00293975,0.085131137,-0.005089305,0.064038826,0.018027905,0.07987319799999999,-1.097371679,-1.4869439919999998,0.618720061,1.33902711,-3.467140909,-2.7840205460000003,-3.3568049319999997,-4.099045433,-4.740491272,-2.355342361,-3.270409808,-1.5921853369999999,-1465.2576128998771 -201,201,A34P,-0.01686929,-0.005024349,-0.746194557,-1.9044930880000002,-2.678125708,0.001235385,-0.00337732,-0.03036126,-0.125354424,-0.02226301,0.012214313000000001,-0.488370254,-1.004018859,-1.834834129,-1.9741520469999998,-2.7259002310000002,-2.6303511840000002,1.7072784380000001,0.801368581,-6.614716512999999,-7.02655616,-6.212445015,-6.988152252000001,-6.84356694,-6.002862198,-6.52291817,-4.304579203,-1461.9735355833545 -202,202,A34S,-0.002500661,0.00589873,0.016221825,0.031552192,-0.245824713,-0.0084807,-0.031467837,0.026466516000000002,0.000378651,0.018720183,-0.006922724,-0.010723483,0.043167132000000004,0.016764636,0.046339748,-0.22144451699999998,-0.270204909,1.3047667520000001,2.012985693,-2.0229628369999997,-2.1525164180000003,-2.186919075,-1.968950966,-2.114584366,-1.6918433609999999,-2.728363201,-1.90000286,-1464.8932774355635 -203,203,A34R,-0.045602501,-0.034062096,-1.115838268,-1.872316469,-3.0640206869999997,0.029656189,-0.030096757999999998,-0.061108243,-0.147087824,0.0028991040000000004,-0.071023295,-0.868813697,-1.362862838,-1.838326464,-1.9063064730000001,-2.632482553,-3.49555882,2.235596009,1.005925638,-5.318845952,-5.352927704,-5.192990135,-6.04935614,-6.13889711,-3.86005867,-4.02107564,-1.234196309,-1464.0922911018133 -204,204,A34T,-0.009567616999999999,-0.023664035,-0.011399072,0.011472821000000001,-0.410171144,0.000905863,-0.030373916,0.011238683000000001,0.053473745999999996,-0.032054077,-0.015273993000000001,-0.02837167,0.005573526,0.010913688000000001,0.012031954,-0.32196398,-0.498378308,1.301585591,1.883329033,-1.477271156,-1.6955034709999999,-1.395476639,-1.5075364690000002,-1.30777063,-1.480068573,-2.003452476,-0.997618545,-1465.9750444567762 -205,205,A34W,-0.026335074,-0.051258753,-0.071276705,-0.017338299999999997,-1.029580625,0.069249331,-0.034185205,-0.018484942,0.053589173,-0.048933444000000006,-0.053584062,-0.127959315,-0.014594093999999998,-0.072415285,0.037738686,-0.836706307,-1.222454942,0.899560783,1.41538364,-4.343234914,-3.86549894,-6.750972022999999,-4.7293356630000005,-4.449731445,-1.9206364980000001,-3.4672374460000004,-2.32485185,-1465.2847781032324 -206,206,A34V,0.033568335,-0.013579021,0.032664643,-0.000632127,-0.029961704,0.045825462000000004,0.018366614,0.048770056,-0.052270977999999996,-0.021534183,-0.005623859,-0.001960592,0.067289878,-0.012851373000000001,0.011587119,-0.049626105,-0.010297302,1.128665717,2.294391512,-1.950976117,-1.27618129,-1.7640052259999999,-2.328176918,-2.58455471,-1.80196244,-1.675558266,0.506115991,-1465.7393278856762 -207,207,A34Y,-0.014001053000000001,0.024321005,-0.022033216,0.03149482,-1.6215608469999998,-0.062116088,-0.024909325,-0.00309278,0.017561056999999998,0.025619385,0.023022624,-0.040192781000000004,-0.00387365,0.073748482,-0.010758842,-1.342080509,-1.901041185,0.5148422020000001,1.317794607,-5.948204324,-7.88748056,-6.921452164,-5.970125244,-6.161019859,-2.8009437939999997,-3.758984041,-0.41003100000000003,-1466.2042989307083 -208,208,E35A,-0.05475229400000001,-0.014474191,0.036780184,0.054124349,-1.787649562,0.085854686,-0.004990799000000001,-0.10451378800000001,0.03151672,0.00956106,-0.038509441,0.017587936999999998,0.055972430999999996,0.06438336900000001,0.043865327999999995,-1.528966365,-2.0463327590000002,0.422109774,1.307128758,-5.929663593,-5.4212415620000005,-6.157147575,-6.011878281,-4.9157176819999995,-7.142332862999999,-4.637283244,-1.338595644,-1452.0974633181468 -209,209,E35C,-0.077656886,-0.005266344,-0.004750114000000001,-1.25494591,-2.420916886,0.006849353000000001,-0.051633728,-0.10368004300000001,0.153330431,0.053455518,-0.063988205,0.009833696,-0.019333924,-0.7632509540000001,-1.746640865,-2.494350531,-2.347483241,0.686898425,0.775656415,-10.56504296,-10.31532274,-9.78569796,-11.55889533,-10.06498613,-11.10031265,-6.725186445,-4.162726006000001,-1449.7419461673126 -210,210,E35D,-0.049983982999999996,-0.05543922,0.055266172999999995,-0.866293229,-2.1195192119999997,0.035918553,-0.011261817,-0.08870614800000001,0.007471576999999999,0.017922578999999998,-0.12880101900000002,0.03070266,0.079829685,-0.44578295100000004,-1.286803506,-2.000195937,-2.238842487,1.573737617,1.358800403,-6.456120277,-5.989195358,-6.651833022999999,-5.221567116,-6.513598357999999,-7.9044075320000005,-5.858720937999999,-3.0953084769999997,-1460.0287887384184 -211,211,E35G,-0.090209224,-0.073698232,0.000316768,-0.785331535,-2.321290613,-0.01236886,-0.04330095900000001,-0.137117488,-0.007883155,0.006389911,-0.153786374,-4.55e-06,0.000638086,-0.40993374899999996,-1.16072932,-2.018537393,-2.624043832,1.543068385,1.3590117519999998,-9.159798047999999,-9.170754501000001,-8.324930481,-9.442117142,-7.633027466000001,-11.22816065,-6.877165706,-3.619510497,-1460.3900456884876 -212,212,E35F,-0.11479157400000001,-0.096938715,-1.271659033,-2.53993936,-2.851699887,-0.003379612,-0.105216903,-0.124366245,-0.050112360999999994,0.052402794,-0.24628022300000002,-1.0900357459999999,-1.4532823190000002,-2.6610502940000003,-2.418828426,-2.5288270109999997,-3.174572762,0.475731045,0.083517909,-11.44289333,-9.704123276,-10.50048055,-14.35192181,-10.80749157,-11.85044943,-6.411293227000001,-2.200181798,-1443.7585262116045 -213,213,E35I,-0.08064698599999999,-0.0054955130000000005,0.037291055,-1.5710226669999998,-2.9875407010000004,0.021542896000000002,-0.055351893,-0.10594207800000001,-0.075997467,0.038356534,-0.049347559000000006,0.027349852999999997,0.04723225599999999,-1.107936126,-2.0341092080000003,-2.929955352,-3.045126049,0.727102253,0.740357232,-9.349729607,-8.783774445,-8.669628281,-10.99530862,-10.3713215,-7.9286151810000005,-5.341833806,-1.557977324,-1445.5389971272089 -214,214,E35H,-0.067183403,0.00048497599999999997,-0.45862226,-1.6972912080000002,-2.7722213730000003,0.038553727,-0.037947849,-0.09641895699999999,0.004969192,0.05469459,-0.053724639000000005,-0.31156148,-0.60568304,-1.661050294,-1.733532122,-2.55001631,-2.9944264360000004,1.411899901,0.775323933,-12.23343287,-11.49127119,-11.79974329,-12.67571156,-12.44503737,-12.75540096,-9.901583493,-8.1113978,-1450.983156003058 -215,215,E35K,-0.081154805,-0.035719008999999996,-0.132693364,-1.6984747519999999,-2.940703589,-0.019899121000000002,-0.034532148,-0.12777746199999998,-0.070547341,-0.015754243,-0.055683775,-0.11270146800000001,-0.15268526,-1.485478216,-1.9114712880000002,-2.871768873,-3.009638305,0.763399323,0.710039475,-7.610294916,-7.12388768,-6.81177607,-9.511837067,-7.7339231029999995,-6.8700506589999994,-6.747037864,-5.06620328,-1455.604702134151 -216,216,E35M,-0.039232433,-0.025135941000000002,0.045301033,-0.46676646200000005,-1.946449764,0.000911017,-0.006715365,-0.0717495,0.00110931,0.0630067,-0.11327858199999999,0.040223086,0.050378979000000004,-0.210724668,-0.722808256,-1.9797780319999998,-1.913121496,1.298937011,1.33185026,-10.6843925,-10.1668725,-10.4805885,-13.3241358,-11.29235183,-8.158013862999999,-7.271198486,-3.67180166,-1447.6156257856637 -217,217,E35L,-0.104493531,-0.05398975599999999,-1.025849724,-2.061794733,-2.8857524789999998,-0.020752785,-0.082659046,-0.126328015,-0.040064222999999996,0.014028477,-0.12200798800000001,-0.608822464,-1.4428769830000001,-2.047072938,-2.076516528,-2.583856436,-3.187648522,1.6938377530000002,0.732852615,-8.891727442999999,-7.988080879,-9.048277542000001,-11.11329454,-9.207010277,-7.101973976,-5.506019502999999,-1.521149934,-1445.3526068418287 -218,218,E35N,-0.022779565,0.01323896,0.033090159,-1.343693211,-2.7417552030000003,-0.001021363,0.033303183,-0.078862312,-0.030973756,0.009403081,0.017074838000000002,-0.008710246999999999,0.074890565,-1.208911328,-1.478475094,-2.456899286,-3.0266111189999996,0.755756999,0.7335341259999999,-10.12875914,-9.110432457,-9.88542495,-10.73626605,-10.65611533,-10.25555692,-8.288531200000001,-5.589610701000001,-1456.2272503389977 -219,219,E35Q,-0.091175329,-0.048267773,-0.015757543,0.0056874809999999994,-0.608613565,0.08717042400000001,-0.092478571,-0.08987208699999999,0.017786863,0.02622783,-0.122763375,-0.024490834,-0.007024251,0.029303091,-0.017928128999999998,-0.462320981,-0.754906148,0.832654265,1.49692326,-5.628269211,-4.975271912,-5.197906532,-6.239145912000001,-5.31126384,-6.417757858,-5.2576390360000005,-3.958922662,-1457.052420037333 -220,220,E35P,-0.04640759999999999,-0.874068752,-1.980774861,-2.26866403,-3.388924727,0.031209828999999998,-0.026228315,-0.066586885,0.046561017999999996,-0.606005945,-1.142131558,-1.928686029,-2.032863692,-2.216399349,-2.320928711,-3.038418575,-3.7394308780000003,1.563351876,-0.022110665,-11.60054997,-11.08789054,-11.04034538,-11.88155006,-11.2649954,-12.7279685,-8.270195519,-6.187353592999999,-1459.6657903962769 -221,221,E35S,-0.041127627,0.0007524869999999999,0.042683544000000004,-0.36569859,-2.463913496,0.030181532999999997,-0.017427633999999997,-0.06482762,-0.046628539000000004,0.041250961,-0.039745987999999996,0.002342739,0.083024349,-0.22442642100000001,-0.506970758,-2.158156118,-2.769670873,1.191564991,1.301815089,-8.41293336,-8.008426086,-7.693069252000001,-9.345964583999999,-8.173151131000001,-8.844055747999999,-6.341116952999999,-3.424305725,-1456.593090894632 -222,222,E35R,-0.104567601,-0.041260662000000004,0.002856633,-1.515880974,-3.10440097,0.023840781000000002,-0.059047925,-0.150087276,0.015605385,-0.027614039,-0.054907284,0.033069712,-0.027356447000000002,-1.198855775,-1.832906172,-2.929955352,-3.278846588,0.562969525,0.717426881,-8.530944912999999,-8.687296027999999,-7.94095298,-8.636654762000001,-8.079344864,-9.310475928999999,-6.614908139,-4.829754618,-1451.8231921815313 -223,223,E35T,-0.076813588,-0.026697341,-0.053754188,-1.514602217,-2.8871426660000004,0.007396326999999999,-0.044531151,-0.109096024,0.014853811000000001,0.003803928,-0.05719861,-0.050295223,-0.057213152,-1.267427468,-1.761776966,-2.265537954,-3.5087473780000002,0.873050732,0.7461894379999999,-8.29855799,-7.909556831000001,-7.356843201,-8.866647652000001,-8.376646805,-8.983095459,-6.524019922999999,-2.5839727359999998,-1452.8246202538721 -224,224,E35W,-0.050557560999999994,-0.32460728699999997,-1.751070295,-2.300249029,-3.040675803,-0.008750991999999999,-0.038171669,-0.062943453,0.015368328999999998,-0.119428861,-0.529785713,-1.433940156,-2.068200434,-2.0438727709999998,-2.556625286,-2.9908307339999998,-3.090520872,0.970529305,0.078243178,-12.10494565,-11.17605563,-11.96057906,-13.83641078,-10.21706438,-13.33461838,-7.24578967,-3.9416303060000004,-1448.5039746221155 -225,225,E35V,-0.112075476,-0.039967375,0.015119378000000001,-1.007319116,-2.288299032,0.063008372,-0.063553663,-0.160597288,0.029912867000000003,0.019433126999999998,-0.099367876,0.047364872999999995,-0.017126117,-0.530785369,-1.483852863,-2.041433766,-2.535164298,1.741530145,1.391816015,-8.895206174,-8.547556992,-8.08642028,-9.265197525,-9.850103485,-8.726752586,-6.490059197999999,-2.03094472,-1446.1396171581 -226,226,E35Y,-0.05961038900000001,-0.05128201,-1.4752130540000001,-2.348920065,-3.049756216,-0.038634016,-0.020131741,-0.09908903599999999,-0.083197172,-0.011766275,-0.090797745,-1.199219286,-1.7512068219999999,-1.9810872,-2.7167529289999997,-3.024955176,-3.0745572560000003,2.389725386,0.9733445740000001,-13.57886199,-11.93632243,-12.60367753,-16.40659492,-13.04974473,-13.89797034,-9.350226271,-7.092387598999999,-1447.1693489747122 -227,227,D36A,-0.041654702,-0.083681227,0.017367946000000002,-0.009070765,-0.005953824,-0.020641471,-0.045974975,-0.037334427999999996,0.001909752,-0.050726318,-0.116636136,0.110959213,-0.076223322,0.022966929,-0.041108458,0.021411218,-0.033318865,1.2585913659999999,2.7027239410000004,1.17832645,2.025713486,0.669059891,1.932755959,1.24298114,0.021121772999999996,-2.390065486,1.1341719940000001,-1467.9314593728632 -228,228,D36C,0.037691899,-0.065358203,0.023380895,0.041438003,-0.09995678300000001,0.02984313,0.041440634,0.033943163,0.15811729300000002,-0.031714413,-0.099001992,0.11501967099999999,-0.068257882,0.067819744,0.015056261000000001,-0.064680243,-0.13523332300000002,1.2655056340000002,2.5041477530000003,-4.122123158,-3.54815966,-4.228758247,-4.134473396000001,-3.938155594,-4.761068893,-6.441918187000001,-4.687457341,-1463.502196224872 -229,229,D36E,0.00149874,-0.055658765,0.008684261,0.03100566,0.001811128,-0.057683422000000005,-0.005926275,0.008923755,-0.045128222999999995,-0.00697742,-0.104340109,0.063509852,-0.04614133,0.08050721400000001,-0.018495894,0.062692427,-0.059070172000000004,1.543610422,3.106887046,0.513113217,0.6949879529999999,0.327084457,0.778792824,0.7219423140000001,0.042758537,-1.8991363430000001,0.31328518899999996,-1457.866893643979 -230,230,D36G,-0.038281083,-0.037177628,0.007476476,0.018158538000000002,0.035435688,0.085444166,-0.056294704,-0.020267461,-0.031177672000000003,0.005444279000000001,-0.079799535,0.084869454,-0.069916502,0.054560987000000005,-0.018243911,0.055260803,0.015610573,1.19868808,2.897576494,-0.896907077,0.13469577800000002,-1.3547222209999998,-0.39862751,-0.495389908,-2.370491524,-2.70406201,-0.909365967,-1465.3576678172685 -231,231,D36F,0.006982974,-0.057743486,0.021463197000000003,0.0059324469999999995,-0.068770939,-0.06399416200000001,0.012960631,0.001005316,-0.086253935,-0.050499308,-0.064987663,0.12085578,-0.077929387,0.046410705,-0.034545811,-0.036829397,-0.10071248099999999,1.237023233,2.517427644,-4.3346790760000005,-3.6897882230000003,-4.303773758,-5.053691238,-3.774185165,-4.851956993,-6.159038138,-4.651269194,-1463.9040387449786 -232,232,D36I,-0.028773653,-0.10785167699999999,-0.041614332999999996,-0.027543459,-0.06987048900000001,-0.040287771,0.004518164,-0.062065469000000005,0.071261357,-0.059895601,-0.15580775300000002,0.00957589,-0.092804556,-0.009285608,-0.045801309000000005,-0.062330925,-0.07741005299999999,1.261343793,2.338969055,-2.4186406540000003,-1.631323639,-2.629121178,-2.597061943,-1.869193184,-3.366503326,-5.043325606,-2.83251096,-1463.6072427476756 -233,233,D36H,0.007738779,-0.079741578,-0.003141004,0.009838892,-0.026165024,0.002515126,0.019838794,-0.0043612370000000004,-0.033572571,-0.08314075,-0.076342406,-0.010712438999999999,0.004430430999999999,-0.016090397,0.03576818,-0.0042884229999999995,-0.048041624000000005,1.203635836,2.578888789,-0.9961859279999999,-0.548338234,-0.64699234,-1.089374222,-0.73636763,-1.9598572159999998,-2.7291433919999997,-1.4964785809999999,-1465.560988794081 -234,234,D36K,0.007690486,-0.053171709000000004,0.051823025,0.050021067999999995,-0.004920756,0.015759236,-0.016535098,0.03191607,0.111138871,0.030581339,-0.136924756,0.11771686199999999,-0.014070812,0.122077103,-0.022034968,0.066865724,-0.076707235,1.0789889559999999,2.8825418289999996,1.325151903,1.7511512830000002,0.975171875,1.549388695,1.664243568,0.685804092,-2.034953443,0.681316508,-1465.6160108181648 -235,235,D36M,0.021369936000000003,-0.059121185,0.049166729000000006,0.06535707,0.060808625,0.048310253,0.013548257,0.029191613999999998,0.003335833,-0.016516555,-0.101725814,0.10957753699999999,-0.01124408,0.067225966,0.06348817400000001,0.094424803,0.027192446000000002,1.132529104,2.9594900689999997,-3.5235213030000003,-3.086010918,-3.51147319,-3.3447618639999996,-2.990655678,-4.684704865,-5.692881476,-3.786905558,-1465.9725526091643 -236,236,D36L,-0.033029527999999996,-0.079211604,-0.005545978000000001,-0.011029001,-0.015402454,0.019561399,-0.034586281,-0.031472774,-0.032523208,-0.0009636139999999999,-0.157459593,0.042316187000000005,-0.053408142,0.035547197,-0.057605199,0.006038258,-0.036843165,1.074439185,2.578544252,-1.7988477109999998,-1.282580879,-1.939139725,-1.752561584,-1.48772892,-2.532227448,-3.692724798,-2.23926373,-1462.7995506543666 -237,237,D36N,-0.041940973,-0.036382781,-0.003001778,0.043017768,0.044241268,-0.030818643,-0.030130111,-0.053751835,0.029920976000000002,0.008510589,-0.08127615099999999,0.055680445999999995,-0.061684002,0.091220654,-0.005185119,0.098314052,-0.009831517,1.053550075,2.9615044530000003,0.015303883,0.191889465,-0.104647171,-0.37290496100000003,0.45298521399999997,-0.090803131,-3.164600886,-0.680816572,-1464.407336327713 -238,238,D36Q,-0.074271277,-0.165097932,-0.024394392,0.008824993,-0.016961135,-0.019975333,-0.102360732,-0.046181821,-0.054743992000000005,-0.10555912199999999,-0.224636742,0.072972902,-0.121761686,0.045708553,-0.028058567000000003,0.030947854,-0.064870123,1.145365088,2.7500961310000003,0.679118826,1.201101547,0.570516068,0.9617561570000001,0.935736923,-0.273516563,-2.095782063,0.24044781699999998,-1466.125183135271 -239,239,D36P,-0.058013956,-0.081964043,-0.018619588,-0.29335164199999997,-2.091987757,-0.047257492000000005,-0.057047676,-0.058980236,-0.065450029,-0.051290960999999996,-0.112637125,0.045483555,-0.08272273,-0.173586388,-0.413116896,-1.844374098,-2.339601416,1.113016357,1.328069427,-3.122200893,-2.461625061,-3.2967239839999998,-3.074876526,-2.626273758,-4.151505135,-5.37002159,-3.2906372860000004,-1466.7515993053094 -240,240,D36S,0.002656817,-0.053904553,0.021143805,0.0112443,0.009267077,-0.037758927000000005,0.005249834,6.38e-05,-0.062645815,-0.0021358220000000003,-0.105673284,0.055568955,-0.013281345,0.045317406,-0.022828807000000003,0.019158097,-0.000623944,0.971461507,2.500686899,1.146971872,1.786855782,0.777179535,1.135468925,1.35343132,0.681923798,-1.175794936,0.23548139399999998,-1465.8458658093587 -241,241,D36R,-0.020563764,-0.042728804,0.029087107,0.029128777999999998,0.049957800999999996,0.007559521,-0.037904493,-0.003223034,-0.038377069,-0.012065483,-0.073392124,0.067943719,-0.009769505,0.05623505,0.002022506,0.041990319000000005,0.057925282,1.1367749120000001,2.734130997,0.48383655200000003,0.550234627,1.162935135,0.997429718,0.34003539299999996,-0.63145211,-2.3234156219999997,0.919638615,-1463.1764701255597 -242,242,D36T,-0.016305262,-0.061606735,0.008844727,0.0032221140000000003,0.006112565,-0.045103232,-0.010731224,-0.021879298999999998,0.009255274,-0.008797199,-0.114416271,0.110882282,-0.093192828,0.045342593,-0.038898366000000004,0.030647421,-0.018422291,1.096146598,2.6734270319999998,0.259143584,0.525711655,0.12210675800000001,1.131858086,0.072347626,-0.556306206,-1.939319155,-0.429911827,-1468.0658202189952 -243,243,D36W,0.025875073,-0.039805279,0.011496518999999998,0.029774255,0.07125018799999999,0.046530532,0.047029115,0.00472103,-0.053315644,-0.029152196000000002,-0.050458362,0.041174085,-0.018181047,0.003281248,0.056267262,0.073345242,0.069155133,1.248661168,2.965849074,-4.6479565460000005,-4.1063635860000005,-4.4226959610000005,-4.963425613,-4.264058922,-5.483238647,-7.031733203,-5.35243121,-1469.6633147955872 -244,244,D36V,-0.012786281000000002,-0.059101552,0.048026803,0.023246056,0.000466563,0.02584015,0.019853914,-0.045426475,-0.053874383,-0.017130443000000002,-0.10107266,0.09881822300000001,-0.002764617,0.022729257000000003,0.023762855,0.042571588,-0.041638463,1.0271103320000001,2.696673147,-1.855441956,-1.300460403,-1.916375,-1.594932251,-1.426581413,-3.03886071,-3.732458621,-2.205054778,-1466.4417182812467 -245,245,D36Y,-0.049795134000000005,-0.107311591,-0.050978622,-0.01491836,-0.165573091,-0.033762522999999996,-0.086623169,-0.012967099,0.07128306200000001,-0.064808225,-0.149814957,0.0019326979999999998,-0.103889942,0.020719816999999998,-0.050556536,-0.120447945,-0.210698236,1.362441836,2.26562992,-3.043504417,-2.388603302,-3.0869060669999997,-3.9590584719999997,-2.226702484,-3.556251762,-5.588143401,-2.9876958339999997,-1465.7656675330363 -246,246,Q37A,0.013475575,-0.034838865,-0.026500827999999997,-0.010441513000000001,0.008497056999999999,-0.020677196999999998,-0.0017371189999999999,0.028688268,0.05390994599999999,-0.046398117,-0.023279612,-0.105808289,0.052806634000000005,-0.08535313900000001,0.06447011400000001,0.0028600340000000004,0.014134078999999999,1.187417751,2.478665957,-2.198182945,-0.82109597,-3.896114616,-1.98023291,-3.4156229710000003,-0.8778482590000001,-5.030943532,0.233595649,-1461.9782039402053 -247,247,Q37C,0.002095961,-0.037353162,0.054402687000000005,-0.0034443909999999998,-0.092868754,0.03202472,0.018661609,-0.014469687,0.136528183,-0.11704468300000001,0.04233836,-0.005949655999999999,0.11475503,-0.079104555,0.072215773,-0.036520699999999996,-0.149216808,1.35029261,2.442460732,-6.265946877999999,-5.166815033,-7.35081115,-6.81415303,-6.505281997999999,-5.49267318,-7.652492333,-3.8525427889999997,-1461.2307096230797 -248,248,Q37E,-0.01183281,-0.029650997000000002,0.012494158,0.044003892999999995,0.004526454,0.096054512,-0.046759292,0.023093673,-0.037504503,-0.017236691000000002,-0.042065302,-0.054194488,0.07918280400000001,-0.030055734,0.11806352,0.013645661000000002,-0.004592754,1.12192323,2.597957697,-1.426059584,-0.395681175,-2.521451088,-2.095011787,-1.5999355469999998,-0.5182183229999999,-3.377207111,0.443794891,-1462.8222808800638 -249,249,Q37D,-0.003060218,-0.022749737000000003,0.037064723,-0.002470336,-0.085462237,0.006734072,-0.012668745,0.00654831,0.056028815999999995,-0.019680931000000002,-0.025818543,-0.043595075,0.11772452,-0.09285454,0.087913868,-0.054366980999999995,-0.11655749300000001,1.360552195,2.329526199,-2.653641107,-1.766590149,-2.321700912,-3.832107391,-3.6569979630000002,-1.69080912,-4.439020311,0.10278575400000001,-1464.680452203378 -250,250,Q37G,-0.009567354,-0.011964871,-0.006138523000000001,-0.016341361999999998,-0.013549446000000001,0.030613001,-0.009323831999999999,-0.009810875,0.057211557,-0.033157149,0.009227407,-0.057139692,0.044862647,-0.063992496,0.031309773,-0.018251812,-0.008847079,1.272649724,2.456592866,-3.9384470339999997,-2.809903435,-4.36294371,-4.994198204,-4.66131871,-2.8638711089999997,-5.416925494,0.105815729,-1466.8196221301332 -251,251,Q37F,-0.03867964,0.014379738000000001,-0.018430252,0.008288437,-0.012968656,0.04203137,-0.017779355,-0.059579924000000006,0.07040608599999999,0.029200746,-0.00044127099999999997,-0.06532956599999999,0.028469063,-0.025370819,0.041947692,0.022214785,-0.048152096,1.15107975,2.558686959,-6.42908054,-6.090999146000001,-6.27020372,-7.059609718,-6.317036606,-6.407553513,-7.886565613999999,-4.25324109,-1457.2098474460654 -252,252,Q37I,0.015214917,-0.012544638,0.026633674,0.004254193,0.009937148,0.022014633999999998,0.013224136000000001,0.017205698000000002,0.029250407000000003,0.03375314,-0.058842415,-0.012489985,0.065757333,-0.009861515,0.0183699,0.024511292,-0.004636997,1.246358117,2.740319173,-5.1079325010000005,-4.5386735080000005,-5.3500802919999995,-5.281901314,-5.302417053,-5.06659034,-6.673518357000001,-3.5687185880000003,-1460.300736987032 -253,253,Q37H,-0.018251094,-0.059180152,0.009643872,0.006968991999999999,0.00280529,-0.044123375,-0.009581504,-0.026920682999999997,0.028903565,-0.023204638,-0.095155666,-0.017266136,0.03655388,0.005619248,0.008318736,-0.011248353,0.016858932,1.107887337,2.59724708,-3.2940336880000003,-2.674552109,-3.5502002939999997,-3.6285799639999996,-3.53234388,-3.084492195,-5.044124948,-2.1848433519999997,-1460.6953107682057 -254,254,Q37K,0.015703717,-0.050748527,0.031059995,0.018645675,0.011905738,0.049587569000000005,0.00772575,0.023681683,0.091976244,-0.049679929000000005,-0.051817124000000006,-0.044590215,0.106710204,-0.029438871000000002,0.06673022099999999,-0.029438871000000002,0.053250347,1.21871546,2.42415044,-1.264592827,-0.49038530700000005,-2.390751076,-1.225363953,-1.352695297,-0.8637685009999999,-2.77053081,0.001415429,-1464.147416619584 -255,255,Q37M,0.022171242,-0.040002664,0.022624394,0.032960689,0.027739205,0.012116823999999998,0.0029941209999999998,0.041348362,0.023764574,-0.035455197,-0.04455013,-0.039614308,0.084863095,-0.034310764,0.100232142,0.042483059000000004,0.01299535,1.075444182,2.612986375,-5.149427977,-4.986198494,-5.539893768,-5.425359909,-5.337031158,-4.458656555,-7.091183707000001,-3.542858139,-1462.288655337412 -256,256,Q37L,0.012956829,0.015188303,0.023039825,0.034235913,0.01388525,-0.019787242,0.020760738,0.005152919000000001,0.025682656,0.018656742,0.011719863,-0.009331208,0.055410858,-0.010290697,0.078762523,0.023704531,0.004065969,1.128423399,2.636717892,-3.516231752,-4.02344722,-3.3292425160000003,-3.333450897,-3.37800827,-3.5170098569999997,-4.87426925,-2.083886688,-1457.972024177201 -257,257,Q37N,-0.007810898,-0.017334184,0.011595097,0.0038964629999999997,0.020191115,0.018040362,-0.00288427,-0.012737526,0.005168492,-0.035902736,0.001234369,-0.056722238,0.079912432,-0.09763997599999999,0.105432901,-0.026521028,0.06690325700000001,1.3624115019999998,2.520843974,-2.824168452,-2.2954244999999998,-2.474125084,-3.895144081,-2.6539424130000002,-2.8022061839999997,-5.1432707660000005,-0.604549101,-1465.0306633333676 -258,258,Q37P,0.022477996,-0.01054113,0.012721455,-1.3091965890000001,-2.202043505,-0.047024175,0.045456844,-0.000500852,-0.017297097,-0.007797084,-0.013285175,-0.027729774,0.053172684000000005,-0.9234519370000001,-1.69494124,-2.050917613,-2.3531693959999997,2.139204527,1.503376333,-5.541554872000001,-4.015758614,-6.828863564,-5.875159439,-6.272567168999999,-4.715425575,-6.365100421,-1.8899330019999998,-1460.4436153764836 -259,259,Q37S,0.011986918999999999,-0.007524843000000001,0.0025294320000000003,0.023025887000000002,0.007432733,-0.007627401,0.017127231,0.006846606999999999,0.073721199,-0.017090793,0.002041107,-0.042124164000000006,0.047183027,-0.022278521000000003,0.068330294,0.014285208999999998,0.0005802569999999999,1.203230196,2.740091345,-2.185639679,-0.899332283,-3.673700256,-2.132792892,-2.413339714,-1.809033249,-5.2105282939999995,0.008645027,-1464.9828049112111 -260,260,Q37R,-0.021317681,-0.004005672,0.007115336,0.015062096,0.03108761,0.022157542000000002,-0.021656908,-0.020978452999999998,0.040234549,-0.005110079,-0.002901264,-0.046307854,0.060538525999999995,-0.014770083,0.044894275,0.027082115,0.035093104,1.33432194,2.864895717,-0.699679449,0.387381828,-1.437676643,-1.080140366,-1.478202469,0.11024040199999999,-2.191038873,0.629104805,-1461.9956009751186 -261,261,Q37T,0.020963225,-0.0351101,0.008072791999999999,0.010537418,-0.011476301999999999,-0.011794971999999999,0.031487932999999996,0.010438517,0.083069955,-0.054105434,-0.016114765,-0.071051344,0.087196927,-0.067702372,0.088777207,-0.004622112,-0.018330491,1.3411160359999998,2.6275328190000002,-2.229295645,-0.862056168,-4.218545348999999,-1.791866051,-2.702212692,-1.5717979659999999,-3.820195376,-0.607356605,-1465.493669772055 -262,262,Q37W,-0.0072093190000000005,0.004655879,-0.00449747,0.017618204,-0.029962936000000003,-0.019107805,-0.023537027000000002,0.00911839,0.023515644,-0.013465428,0.022777186,-0.040018372,0.031023432000000004,-0.031029987000000002,0.066266395,-0.004012933,-0.055912939,1.2989874609999998,2.651238149,-5.941871494,-5.351138023,-6.511625777999999,-6.232775169,-6.121073639,-5.492744857999999,-7.24363798,-4.244214405,-1460.9394943844527 -263,263,Q37V,0.005571385,-0.014868846000000002,-0.008102534,-0.008003736,-0.009010772,-0.001559684,-0.02375958,0.03490235,0.030535424,-0.051932205,0.022194513,-0.057983344000000006,0.041778276,-0.076168127,0.060160655,-0.010336604000000001,-0.00768494,1.276755325,2.5206573519999997,-4.566301718,-4.351111183,-4.948481682,-4.371912758,-5.398552505,-3.761450462,-6.117442707,-2.677320645,-1463.2417292576283 -264,264,Q37Y,0.032321182000000004,-0.013275173999999999,0.009741443,0.016868122,-0.050090694000000005,-0.010390251,0.015933753000000002,0.04870861,0.06277607,-0.046523644,0.019973296,-0.113911245,0.133394131,-0.076492015,0.11022825900000001,-0.025178816,-0.07500257099999999,1.4371617419999998,2.522602388,-5.651566237000001,-4.83251799,-5.976137802,-6.497289169,-5.6371358570000005,-5.314750366,-7.424068471,-3.309527611,-1457.2830195529386 -265,265,L38A,-0.036084275,-0.024499052,-0.025508815,-0.032336151,-1.5811186469999998,0.097808454,-0.016201131,-0.055967418,-0.069158477,0.014315446,-0.06331355,-0.008105304,-0.042912325,-0.005063157,-0.059609144,-1.264756797,-1.897480496,0.760242283,1.339958771,-8.685752034,-7.431558624,-8.695046364,-7.080600166,-10.66182262,-9.559732391,-3.94502692,0.37195350299999996,-1469.1549604428 -266,266,L38C,0.032500706000000004,0.054308275999999996,0.036401874,-0.051520496,-2.132422185,0.07841328,0.073338782,-0.008337371,0.030227026,0.067964805,0.040651747,0.00962721,0.063176538,-0.05262911,-0.050411882000000005,-1.9428911619999998,-2.321953207,0.8205808529999999,1.303259792,-10.53306749,-10.61580608,-9.699528091,-11.2616125,-12.13649152,-8.951899254,-6.358900087,-2.277954587,-1463.7762383129448 -267,267,L38E,0.007020666,0.053261009000000005,0.015303333999999998,0.027263698,-1.69693259,0.080244211,0.026734182999999998,-0.012692852,-0.10530061800000001,0.04805206099999999,0.058469956,-0.034849075,0.065455742,0.031571889,0.022955507000000003,-1.494596234,-1.899268945,0.7444425809999999,1.324672427,-11.38094572,-11.95427306,-10.10961348,-12.08169437,-12.03071597,-10.72843171,-6.443532824,-2.41408747,-1456.6049162978306 -268,268,L38D,-0.018575298,0.030273038,0.026986523999999998,0.07572081900000001,-1.72549043,0.051976555,-0.04156863,0.004418035,-0.148596904,-0.039460178,0.100006253,-0.024509668,0.078482716,0.078367198,0.07307444,-1.573675305,-1.877305555,0.62541432,1.313824582,-11.45223208,-12.36083303,-10.19883658,-12.47675761,-11.56261189,-10.66212132,-5.705134796,-2.5023196469999998,-1460.4464373872615 -269,269,L38G,0.000641591,0.016289419,-0.022557695,-0.019264259,-1.413216117,0.088820831,0.038925307,-0.037642125,-0.041049764,0.036695868,-0.004117031,0.002617341,-0.04773273,-0.029052161,-0.009476357,-1.007953808,-1.818478426,0.826863204,1.3733831509999999,-11.38058441,-10.71061833,-10.76401826,-11.52271614,-12.20099622,-11.70457311,-5.774860003,-2.00599906,-1465.873271371238 -270,270,L38F,0.009911524,-0.01435726,0.039812405,-0.041355939,-0.674853968,0.093093476,-0.00657086,0.026393907,-0.18542828,-0.020990791,-0.007723729,0.0007798130000000001,0.078844996,-0.073624862,-0.009087016,-0.436949398,-0.912758538,1.200856462,1.682244233,-6.442623038,-9.133624146,-4.64315345,-6.614286224,-5.674581047,-6.147470322,-4.481184371,0.398168927,-1469.5373694649898 -271,271,L38I,0.021416114,-0.032329569,-0.031169739,-0.049498635,-0.372458419,-0.010307277,0.023948795,0.018883432,-0.207756202,-0.055727949000000006,-0.008931189,-0.050159115,-0.012180363,-0.069728123,-0.029269146,-0.29554569399999997,-0.449371144,1.4712114630000002,2.0052156709999998,-3.483750658,-3.818187271,-3.2832077639999997,-3.981381401,-3.5568825530000003,-2.7790942989999996,-3.80013138,-1.237287984,-1467.0165863526054 -272,272,L38H,0.027157683,0.007122961,-0.00741479,-0.034864848,-1.263921658,0.070474713,0.034447543,0.019867822,-0.11199431900000001,0.008734496999999999,0.005511425,-0.031509125,0.016679546,-0.06598458,-0.0037451159999999997,-1.049702618,-1.478140697,0.978687832,1.3957291369999998,-10.21470181,-11.35886645,-8.569752869,-11.82796991,-10.57031552,-8.746604286,-4.116264684,-0.169269112,-1464.611336864531 -273,273,L38K,-0.077827682,0.035299117000000005,0.003382869,-0.067947336,-2.224309184,0.134057691,-0.02282425,-0.132831113,-0.20708471,0.048881282000000005,0.021716951,-0.006466384,0.013232121000000001,-0.023621074,-0.112273598,-1.823281259,-2.625337108,0.58159807,1.301765008,-10.89395408,-13.39562808,-8.650029572000001,-11.49820211,-10.24843256,-10.6774781,-5.561402256,-0.434391011,-1453.4306736355647 -274,274,L38M,0.006844301999999999,-0.013503707,-0.039752019,-0.018308208,0.039525158,0.110577646,0.027613086000000002,-0.013924482,-0.125715083,-0.035207978,0.008200564,-0.04085002,-0.038654018,-0.035917984,-0.000698432,-0.040556189,0.119606504,1.450314855,2.5612840080000003,-7.186625591,-7.741253426,-6.658322807,-7.053589256,-7.343015472,-7.136946991,-6.487837799999999,-2.784617623,-1465.784471313469 -275,275,L38N,-0.021271976,0.082115635,-0.035783916,0.016296568,-1.721639345,0.043558539,-0.005108255,-0.037435697000000004,-0.115417752,0.046178734000000006,0.118052535,-0.056739645,-0.014828186,0.011706006000000001,0.02088713,-1.446386409,-1.996892281,0.739385411,1.326643906,-10.91688667,-12.83726284,-8.678019066000001,-12.49053517,-12.18524563,-8.393370628,-5.327972442,-1.71684058,-1466.304065872915 -276,276,L38Q,-0.042838182999999995,0.005543534,-0.015836337,0.028416585,-1.495932181,0.084381077,-0.049628574,-0.036047792,-0.033398221,0.03924487,-0.028157803,-0.030102768,-0.001569906,0.000670087,0.056163082,-1.598395473,-1.3934688880000001,0.615607525,1.311533522,-9.822292548,-10.91223233,-8.581262557999999,-11.12782203,-9.336752007000001,-9.153393814,-6.016036565,-1.6311621040000002,-1459.9523116257042 -277,277,L38P,-0.022086388,-0.020702261,-0.037503621,-0.046259049000000003,-1.51455909,0.045366008,-0.009084821,-0.035087954,-0.111735146,-0.011554845,-0.029849676000000002,-0.049179342,-0.025827898999999998,-0.051786025,-0.040732073,-1.4183522519999998,-1.6107659269999999,0.707074608,1.327017295,-12.70543403,-14.05712273,-11.88686693,-12.43411126,-13.13324912,-12.01582009,-7.162804476,-2.6217315080000003,-1464.625416456256 -278,278,L38S,-0.025628826,0.005934258,-0.015047861000000001,-0.047805993,-0.8845963490000001,0.091171065,-0.016748463,-0.034509187999999996,-0.064305145,0.037833043999999996,-0.025964527999999997,-0.012456077,-0.017639645,-0.051836854,-0.043775130999999995,-0.656627583,-1.1125651140000001,1.111638181,1.5350994059999998,-7.654905255,-7.71889605,-6.487159119,-8.63528656,-9.574180823999999,-5.859003723,-3.237204007,0.051233415,-1467.4128566025756 -279,279,L38R,-0.008876925,0.002090757,-0.021993545,-0.217223563,-2.052487335,0.053667173,0.015666904,-0.033420754,-0.104741429,0.028816124,-0.02463461,-0.057494235,0.013507145,-0.17541948300000001,-0.25902764300000003,-1.9212492369999998,-2.1837254319999997,1.326826835,1.32411559,-10.3081636,-11.06804789,-9.447527877999999,-10.83105425,-10.43445696,-9.75973101,-4.772213727,-1.7088745269999999,-1451.951381040737 -280,280,L38T,-0.006831895,0.036676415,-0.01770499,-0.027612948,-0.369701482,0.11676921800000001,0.001163389,-0.014827178,-0.133721363,0.005189216,0.068163614,-0.042459897,0.0070499180000000005,-0.037734465,-0.01749143,-0.34616000399999997,-0.393242959,1.207653389,1.7671813280000002,-7.403314152999999,-7.900249412999999,-7.485204109,-7.089641296,-10.19161333,-4.349862617,-4.490535058,-0.680221755,-1464.6856474271044 -281,281,L38W,0.007240236,0.008649317,0.01615162,-0.061031971,-0.62371773,0.163826682,0.015014261000000001,-0.000533789,-0.09368677199999999,-0.008158053,0.025456687000000002,-0.013508343999999999,0.045811584,-0.105235619,-0.016828323,-0.460997393,-0.7864380670000001,1.660141949,1.997512823,-12.24511037,-13.64904004,-10.95416203,-13.3831639,-11.896614999999999,-11.34257085,-7.489689975,-4.691202126,-1464.2329969895072 -282,282,L38V,-0.078594625,-0.025269512999999997,-0.050148182,-0.024244138,-1.6602376840000002,0.081376983,-0.053496515999999994,-0.10369273300000001,-0.108244041,-0.005891084,-0.044647941,-0.040916537,-0.059379826,-0.006722659000000001,-0.041765616,-1.313408125,-2.0070672430000003,0.81897376,1.340261743,-4.433360303,-3.689975327,-3.934018967,-4.921222176000001,-5.044612007,-4.576973038,-3.409149002,-0.885409642,-1468.0886684693396 -283,283,L38Y,-0.020096759,0.006630871,0.026163047000000002,0.008026452,-0.342970173,0.138370292,-0.031373708,-0.00881981,-0.133750813,0.026584873,-0.013323132,0.05059633400000001,0.00172976,-0.020492756,0.036545659,-0.23793565100000003,-0.448004694,1.5088789669999998,2.143939584,-10.25337876,-13.24119003,-7.650171768,-11.66278089,-9.965408973999999,-8.747342125,-3.964063777,0.095320722,-1465.5282765026204 -284,284,G39A,-0.018175581,-0.017296823,0.004159079,-0.016124848,-0.051723869000000006,0.0064381690000000005,-0.010421729,-0.025929432000000002,0.016051568999999998,-0.053339385999999996,0.01874574,-0.0020444639999999997,0.010362620999999999,-0.017374096000000002,-0.014875599,-0.075227393,-0.028220345,1.26573419,2.330842986,-2.305557086,-2.1833595580000003,-2.411863701,-1.314909004,-2.6280638730000003,-2.989589294,-2.287964036,-2.369941989,-1463.2402970967814 -285,285,G39C,-0.10714680000000001,-0.125044225,-0.08729745,-0.020649595,-1.1095863209999999,0.005034329000000001,-0.098605507,-0.11568809199999999,0.066509415,-0.056326918,-0.19376153100000001,0.003578724,-0.178173623,-0.006897919000000001,-0.034401271000000004,-0.65553961,-1.5636330319999998,0.9523379059999999,1.476119502,-5.220351968,-4.784487816,-5.658764175,-4.626481644,-5.418281311,-5.613744896,-5.2358188189999995,-5.899151552,-1459.147043833509 -286,286,G39E,-0.025114555,-0.032570732000000005,0.001576919,0.020539605,-0.046368472,-0.003987683,-0.007564349000000001,-0.042664760999999995,-0.012997076000000002,-0.029316732999999998,-0.035824731,0.012801753,-0.009647915,0.011229612,0.029849597999999998,-0.013169385,-0.07956755900000001,1.238612166,2.494572306,-2.20269892,-1.9515571369999998,-2.872245552,-1.645568146,-1.419238785,-3.124884979,-3.027045757,-2.233849494,-1467.8744287067093 -287,287,G39D,-0.059309297000000004,-0.038062946,0.005496867,-0.004272313,-0.041516898999999996,-0.027531486,-0.023204581000000002,-0.09541401199999999,0.018124438,-0.005584921,-0.070540971,0.02451263,-0.013518896,0.025626481,-0.034171106,-0.002435793,-0.080598004,1.267745653,2.641942283,-0.9055096309999999,-0.975800125,-0.892875961,-0.47951193200000003,-0.39023509999999995,-1.7891250380000001,-1.172135141,-0.805415896,-1469.3654601653107 -288,288,G39F,-0.086846373,-0.094038668,-0.016561159,0.042664764,-0.618090784,0.07120549400000001,-0.055588349,-0.118104396,-0.003064861,0.000366854,-0.18844418899999998,-0.00603342,-0.027088897999999997,0.074718945,0.010610583,-0.426546364,-0.8096352040000001,0.9214798470000001,1.553908355,-6.09310014,-7.246628754,-6.4078273160000006,-4.290616417,-6.033911934,-6.486516281,-6.460641067,-6.974351762,-1457.09598830482 -289,289,G39I,-0.146795925,-0.06749095,-0.017118722,-0.033975706,-0.672065611,-0.066558822,-0.085044732,-0.208547117,0.014665743,-0.04542732,-0.08955458,-0.007172792,-0.027064652,0.019291037,-0.08724244800000001,-0.45840476,-0.885726462,0.966541471,1.5578645930000001,-6.164445897,-6.177320816,-6.779677895,-4.94606192,-5.879094887000001,-7.0400739670000005,-5.19630328,-4.449055163,-1457.3957401933149 -290,290,G39H,0.057380417999999996,-0.031844157000000005,-0.024760737999999997,0.009028342,-0.053090858,-0.033920782000000003,0.02622844,0.088532396,0.020842595,-0.026238516,-0.037449798,-0.04723196,-0.002289516,0.002937275,0.015119408999999999,-0.000261691,-0.105920025,1.2715196579999999,2.6078093630000003,-0.519858377,-0.205048973,-1.7921976469999998,0.47482469200000005,0.109065681,-1.185935638,-2.002675836,-2.541995413,-1463.7435014303774 -291,291,G39K,-0.062437232999999995,-0.068582407,-0.025821892000000003,-0.019795206,-0.058406355,-0.040259006,0.034325895,-0.15920036,0.017189466,-0.08575820099999999,-0.051406613,-0.007031838,-0.044611946,-0.033597508,-0.005992903000000001,-0.024390306,-0.092422404,1.290710816,2.510587795,-0.19001675699999998,-0.814647453,-1.333052483,1.27691851,1.339176514,-1.418478874,-1.314500354,-1.251868861,-1470.0805229595862 -292,292,G39M,0.024295061,-0.023338721,0.038627133,0.065037206,-0.157725137,-0.035261502,0.074765832,-0.02617571,0.15822439300000002,-0.05758651099999999,0.010909068999999999,0.001256386,0.075997879,0.049841561,0.08023285,-0.133789397,-0.18166087600000003,1.3870124259999999,2.26346973,-5.676114206,-5.449192062000001,-5.720592445,-5.155404076,-5.699067832999999,-6.3563146129999994,-4.8840753910000005,-5.058667077,-1460.030018787831 -293,293,G39L,0.013008287,-0.046049085999999996,0.004741495,0.018861325,-0.17984062399999998,-0.040992234,0.018079874,0.0079367,0.045538765,-0.00752326,-0.084574911,0.036195931,-0.026712942000000003,0.029803871000000003,0.007918778000000001,-0.11534632,-0.24433492699999998,1.457873556,2.38527137,-5.367090427,-5.132965263,-5.8937718960000005,-4.6914292369999995,-4.9553363269999995,-6.161949409,-4.844458766,-5.120264332,-1453.9389881421812 -294,294,G39N,-0.066750461,-0.042494082999999995,0.021690282999999998,-0.013061568,-0.119873344,-0.067529727,0.01096705,-0.144467971,0.190629885,-0.033411321,-0.051576845,-0.003898685,0.047279250999999994,-0.027336935,0.001213799,-0.045853334,-0.193893354,1.356320925,2.474560575,0.505353918,0.071031845,-0.110237968,0.91164846,1.684766953,-0.030439697,-0.82847736,-1.48990894,-1469.2864017388783 -295,295,G39Q,0.09231882699999999,-0.024939292000000002,0.040726235,0.043551306,-0.004546878,-0.0041139259999999995,0.06438384700000001,0.12025380699999999,0.115921951,-0.000718656,-0.049159927,0.035170699,0.046281771,0.033272204,0.053830407999999996,0.013390613999999999,-0.022484369,1.1296082570000001,2.565841638,-0.461877621,-0.255409485,-1.3766799619999999,0.569256279,0.57329216,-1.819847099,-2.290038971,-1.841318519,-1466.4101345865056 -296,296,G39P,-0.024957788999999998,-0.023815927999999997,-0.027370962999999998,-1.121844931,-2.311613621,-0.010413806,0.00324641,-0.053161988,-0.020773369,-0.033664415,-0.013967441,-0.042311783,-0.012430143000000001,-0.6698080670000001,-1.573881794,-2.280075389,-2.343151853,1.7315836080000002,1.314917237,-1.847444026,-0.902795815,-1.693601044,-1.3556551209999999,-1.9326427990000001,-3.352525352,-1.685002017,-1.355652664,-1458.7685361411422 -297,297,G39S,-0.002436374,-0.033435636,0.019670545,0.011983062,-0.054611988,0.011320493000000001,0.041432215,-0.046304963,-0.077682494,-0.059012616,-0.007858656,0.03036699,0.008974099000000001,-0.020358901999999998,0.044325025,-0.020828144,-0.088395832,1.244729067,2.519156176,-0.96456564,-0.045579918,-1.325084709,-0.114295891,-1.408460999,-1.929406685,-1.6400115869999998,-1.625222164,-1462.517632106319 -298,298,G39R,0.035641591,-0.033352858,0.005775274,-0.003476574,-0.042271582,0.020859922,0.066997714,0.004285467,0.008114535,-0.058159105,-0.008546610999999999,-0.013072561000000002,0.024623107999999998,-0.03597721,0.029024062000000003,-0.031714287,-0.052828877,1.1952619359999999,2.412936074,-1.525261711,-1.30752224,-2.627572128,-0.349559258,-0.996594505,-2.345060425,-2.464090906,-2.207126206,-1464.5963683719747 -299,299,G39T,-0.016386802,0.005647872,0.004195953,-0.003613952,-0.22832972899999998,-0.019381086999999998,0.058367178,-0.09114078099999999,-0.010284956999999999,-0.051187279,0.062483022,-0.005450593,0.013842499,-0.056765373,0.04953747,-0.195486475,-0.261172983,1.4907399280000002,2.179379286,-2.804179903,-2.512974579,-2.897444412,-2.152659828,-3.0122260819999997,-3.445594612,-2.919464024,-3.01860165,-1458.7100841635838 -300,300,G39W,-0.028442852,-0.009634091,0.022805716,0.027869203,-1.518050793,0.04987663,0.013734525,-0.070620228,0.096671626,-0.014407323,-0.004860859,0.003127785,0.04248364599999999,-0.025102963,0.080841368,-1.222811367,-1.813290219,0.625418467,1.332678085,-5.778988435,-6.06773716,-4.958365845,-5.07958783,-5.640652596,-7.148598747,-5.718269942999999,-5.42346743,-1462.9166147429496 -301,301,G39V,-0.01442503,-0.019213564,-0.0022054139999999997,0.031149303,-0.19385058100000002,0.004199489,0.015830909,-0.044680968,0.079504576,-0.012016053,-0.026411075,0.007491108000000001,-0.011901935,0.018866093,0.043432513,-0.172887636,-0.214813525,1.474813867,2.236658008,-4.954182257,-4.526209999,-5.442019844,-3.551391846,-5.31167952,-5.939610077,-4.500919474,-4.311133515,-1458.3419863739982 -302,302,G39Y,0.020294346,-0.057338407,0.054551467,0.011123401000000002,-0.821028526,-0.036919294,0.066726116,-0.026137424,-0.07454260900000001,-0.054360603,-0.060316210999999995,0.11705783800000001,-0.007954905,0.009527161,0.012719641,-0.49911105100000003,-1.142946,0.8808130940000001,1.505869713,-5.663334793,-5.608340179,-5.750419746,-4.488738876,-6.1968257289999995,-6.272349434,-6.708557884,-7.515189007999999,-1460.7566330768168 -303,303,A40C,-0.105117456,-0.058843793,-0.07350666900000001,-0.010672741999999999,-1.570195837,0.10665125800000001,-0.075370656,-0.134864256,0.012803258999999999,-0.029218284,-0.088469301,-0.0290485,-0.11796483699999999,-0.009296999,-0.012048485,-1.4922726130000001,-1.64811906,0.717687273,1.32311566,-9.076272589,-9.335064285,-8.492576012,-10.19004385,-7.921906654,-9.441772141,-5.2637627,-3.171816914,-1450.329741015099 -304,304,A40E,-0.06306977700000001,0.00224266,-0.022318402,-0.570752814,-1.945210291,-0.01115715,-0.031995033,-0.094144521,0.0007542689999999999,0.023306201000000002,-0.018820882,-0.024049865,-0.020586939,-0.300689456,-0.840816172,-2.088340444,-1.8020801380000002,1.360774921,1.321849991,-8.268409337000001,-7.952552399,-8.905314232,-7.445812537999999,-7.368665732999999,-9.669701782,-5.624080508,-4.453475657,-1462.5210783747025 -305,305,A40D,-0.05477293,0.005328475,-0.07492737299999999,-0.5582535470000001,-2.183416924,0.016838642,-0.057307363,-0.052238495999999995,-0.042208472000000004,0.029860412000000003,-0.019203462,-0.082346915,-0.06750783,-0.33490974,-0.781597353,-1.9787366469999998,-2.3880972000000003,1.484087322,1.3536285890000002,-9.115126808,-9.163704842000001,-9.302482513,-8.422225395,-8.19860421,-10.48861708,-6.013749868,-5.1557538339999995,-1462.5430755843408 -306,306,A40G,-0.022685054,0.004718077,-0.044784395,0.015946553999999998,0.036494768,0.07070687,-0.027993855,-0.017376252,0.012355061,-0.014622848,0.024059001,-0.030248333999999998,-0.059320455,0.036542207,-0.004649100000000001,0.053630682,0.019358853,1.0961339490000002,2.600588944,-0.157101077,-0.468017731,-0.370095764,-0.025973915,-0.015459946,0.094041969,-1.312565006,0.5455119070000001,-1455.1296431776136 -307,307,A40F,-0.10365336900000001,-0.03218484,-0.066587457,-1.287011271,-2.38393397,-0.002454684,-0.074610804,-0.13269593300000002,0.121574302,0.021951617000000003,-0.08632129599999999,-0.05502172,-0.07815319400000001,-0.875162581,-1.69885996,-1.996110743,-2.7717571960000003,2.128698785,1.51933801,-11.64279599,-12.05313537,-10.62418295,-15.23865742,-10.27326093,-10.02474327,-5.9435427139999994,-3.972397033,-1454.566019535996 -308,308,A40I,-0.094116576,-0.016606757,-0.023440445,-0.419960007,-1.756061106,-0.027451167000000002,-0.09981725,-0.08841590099999999,0.232006767,-0.048122929,0.014909415,-0.08361801599999999,0.036737127,-0.289957244,-0.549962769,-1.8782668230000001,-1.633855389,1.3985434630000002,1.356202295,-9.896002504,-11.21368596,-9.155639022999999,-11.12650687,-7.659156036000001,-10.32502463,-5.093383976,-3.349739284,-1443.9208009159192 -309,309,A40H,-0.038118501,0.015070941000000001,-0.037597731,-1.4119757430000002,-2.788829598,0.000639644,-0.030914637000000002,-0.045322365,-0.019298419,0.003121459,0.027020422000000002,-0.063391787,-0.011803675,-0.802521851,-2.021429634,-2.386422312,-3.191236883,1.7821190630000001,1.264502866,-11.03103163,-11.40243981,-11.17949748,-11.79677647,-9.29396254,-11.48248183,-6.857150458,-5.841770338,-1456.4113119277172 -310,310,A40K,-0.09380111699999999,0.002298994,-0.155132471,-1.65717812,-2.764567772,0.049789712,-0.047072530999999994,-0.140529703,0.07926064,-0.008597839,0.013195827,-0.053988032000000005,-0.25627691,-1.137884574,-2.176471666,-2.659977884,-2.86915766,0.701938127,0.7348556490000001,-9.688825706,-10.28332585,-9.40587561,-10.43470382,-7.870976142999999,-10.44924711,-6.196180974,-4.554303697,-1462.5273943720385 -311,311,A40M,-0.033500351,-0.014801061,-0.04989851,-0.022023066,-1.027279569,0.026258481,-0.012748255,-0.054252445999999996,0.082907491,-0.064487197,0.034885075,-0.08480563099999999,-0.014991388000000001,-0.033325443999999996,-0.010720688,-0.740214699,-1.314344438,0.756267169,1.407117765,-9.717348702999999,-10.64748917,-9.038460899,-11.74316519,-8.140702957,-9.016925301,-5.942501655,-5.028209158999999,-1459.9995151786134 -312,312,A40L,-0.035231611,-0.010382304,-0.060243122999999996,-0.37685451600000003,-1.9776782069999999,-0.05162157,-0.041155282,-0.02930794,-0.03724315,-0.008569522,-0.012195085,-0.097916445,-0.022569801,-0.19898199100000002,-0.554727041,-2.008126796,-1.9472296169999999,1.3632733559999999,1.336924195,-9.107283621,-9.785855507,-8.010775436,-11.31403778,-7.249760802999999,-9.175988579,-4.965379495,-1.602838039,-1452.5755171012133 -313,313,A40N,-0.071405342,-0.053581252,-0.133728755,-0.040425194,-1.691389934,0.009492687,-0.116351687,-0.026458996000000002,-0.079912859,-0.122423627,0.015261124,-0.223380528,-0.044076980999999994,-0.078624613,-0.002225775,-1.697627936,-1.685151932,0.9804753559999999,1.329809824,-9.744348192999999,-10.28625108,-8.746045074,-10.45251505,-8.457188736,-10.77974103,-6.111152576,-4.520367236,-1458.2893835678697 -314,314,A40Q,-0.053653174000000005,-0.007756886,-0.03961109,-0.036845682000000005,-0.538026022,0.006859272,-0.04486314,-0.062443208,-0.074541658,-0.000211073,-0.015302698,-0.028539832999999997,-0.050682347,-0.007673269,-0.066018094,-0.37028403,-0.7057680129999999,0.9682510390000001,1.610034084,-9.733010066,-10.40476114,-9.48382283,-10.2149325,-8.156155273,-10.40537859,-6.305973184,-5.44235615,-1460.2342409067787 -315,315,A40P,-0.07962617,-0.034216582,-0.460880511,-1.8780468190000001,-2.675154675,-0.01378096,-0.062021519000000004,-0.097230821,-0.02543906,-0.041674732,-0.026758432000000002,-0.335497833,-0.586263189,-1.695279206,-2.060814432,-2.35490038,-2.99540897,1.469623919,0.776240657,-9.377176689,-9.265714676,-9.840518715,-9.610538567,-7.831010452,-10.33810104,-6.788661962999999,-5.546441044,-1462.513309632428 -316,316,A40S,-0.06026332,-0.017610296,-0.066653575,-0.015269671,-0.15070486,0.016593883,-0.064965621,-0.055561019,-0.002819204,-0.001710085,-0.033510507,-0.055722437,-0.077584712,0.020832589,-0.05137193,-0.100199099,-0.201210621,1.250644771,2.261861384,-5.264974377,-5.080157265,-4.909791092,-5.498686325,-4.608633636,-6.227603568999999,-4.436118249,-3.761126163,-1454.851006275043 -317,317,A40R,-0.092813762,-0.008191595,-0.37600203,-1.83979727,-2.49902172,0.036859048,-0.06776038,-0.11786714400000001,0.000722387,-0.010637048999999999,-0.005746141,-0.299719432,-0.45228462700000005,-1.4758914140000001,-2.203703125,-2.43264754,-2.5653959,1.568285453,0.86188763,-9.219595867999999,-10.81506764,-10.715207800000002,-9.241713127,-6.7980230939999995,-8.527967674,-4.636907077,-4.139446339,-1461.6509046913125 -318,318,A40T,-0.060567583,-0.00658904,-0.065936878,0.008830971,-0.47443829200000004,0.032575306,-0.065806562,-0.055328603,0.013220431999999999,-0.008632731999999999,-0.004545347,-0.084649827,-0.047223928,0.010730045,0.006931896,-0.372457896,-0.576418687,1.5843888030000002,2.034189763,-6.061827898,-6.02127092,-6.374774521,-6.46300911,-5.088188705,-6.3618962329999995,-4.341103513999999,-3.264619475,-1458.7954540569335 -319,319,A40W,-0.086372996,0.034520409,-0.066124692,-0.3816922,-1.9231337169999998,0.053237823,-0.060273583,-0.11247240900000001,0.028829628,0.006846049,0.062194768,-0.09071809800000001,-0.041531285,-0.22501643699999999,-0.538367963,-1.8176908219999999,-2.028576611,1.3696194869999998,1.3634874019999998,-9.56096591,-9.665654472,-8.352868759,-12.55354668,-7.67288636,-9.559873283,-5.210615845,-4.674515845,-1464.7958146473393 -320,320,A40V,-0.028467917000000002,0.012072437,-0.034846281,0.011812778000000001,-1.766813589,-0.002176936,-0.021491331000000002,-0.035444502999999995,0.017451831,0.02022624,0.0039186329999999995,-0.043448358,-0.026244204,0.062826097,-0.039200542000000005,-1.531854271,-2.001772906,0.620901931,1.315117069,-7.295956834,-8.534280052,-6.822046332999999,-8.301037498,-6.192158562,-6.6302617260000005,-3.547302239,-1.71421689,-1458.7095051114447 -321,321,A40Y,0.016384013,-0.002946518,0.029702202,-1.492155119,-2.342321982,0.049562407,0.04584061,-0.013072585,-0.0072198440000000004,-0.00249084,-0.0034021959999999997,-0.010566461999999999,0.069970865,-1.09567298,-1.8886372569999998,-2.024139467,-2.660504497,2.277840302,1.555949434,-12.55424095,-12.88309465,-11.62149262,-15.76607797,-11.04554511,-11.45499439,-6.028284081,-4.387712206000001,-1451.1004663663916 -322,322,R41A,0.014175223,0.0011350330000000001,-0.005289116,-0.016504862,-0.329086585,-0.024127067000000002,0.028168900000000004,0.000181545,-0.000805686,0.013836642,-0.011566576,0.026436757999999998,-0.03701499,0.016264429,-0.049274152,-0.24748700399999998,-0.410686165,1.075702019,1.8031354780000002,-7.9110335329999995,-8.454929474,-7.594357742000001,-8.198534317,-6.476770332,-8.830575798,-6.496754075,-3.516781603,-1444.790596849285 -323,323,R41C,0.036169782000000004,0.038635089,0.014229368999999999,-0.348469811,-1.6935093490000002,0.013772578,0.076069142,-0.003729578,0.107267498,0.003083749,0.074186428,0.001910194,0.026548544,-0.161939826,-0.534999795,-1.654782867,-1.73223583,0.995172686,1.3341927,-10.90790401,-11.80925703,-10.84698395,-11.5463815,-9.791303535,-10.54559406,-10.07774203,-9.472095529,-1449.3526247101836 -324,324,R41E,0.026797447000000002,-0.143173155,-0.006802989000000001,0.11204932699999999,-1.8836354180000001,-0.17588869699999998,0.076386644,-0.022791751000000002,-0.304943142,-0.097306448,-0.189039861,0.008005655,-0.021611632000000002,0.14380294300000002,0.08029571099999999,-1.76744391,-1.999826925,0.582131696,1.3039415429999999,-7.229512217999999,-8.779807655,-7.426165421,-7.652133903999999,-5.51179612,-6.77765799,-5.996768207000001,-2.101125874,-1441.4818202713504 -325,325,R41D,0.0011484730000000001,0.034898487,0.031915898,0.011613871000000001,-1.9552650969999998,-0.055899153,0.026722857000000003,-0.024425912,0.045136250999999995,0.026786535,0.043010439000000004,0.053678644000000005,0.010153152,0.06180162,-0.038573879,-1.63579779,-2.274732404,0.554420618,1.3082232059999999,-7.130674689,-9.39888298,-7.688447707999999,-7.349585938,-4.913296463,-6.303160355,-5.369035478,-2.072761667,-1443.2940827445127 -326,326,R41G,-0.045227413,-0.008654291,-0.013518428999999998,-0.272394316,-1.9746788119999998,-0.005760957,-0.015736165,-0.07471866099999999,-0.011328907,-0.017192073999999998,-0.000116507,-0.012607344,-0.014429513,-0.17475639199999998,-0.370032239,-1.870903855,-2.0784537690000002,1.113777737,1.325451707,-8.174043091,-8.158225319,-8.015790512,-8.991767075,-7.331984467000001,-8.372448082,-6.738433802,-4.347049413,-1443.564104521647 -327,327,R41F,-0.031995134,-0.066353486,0.024488762999999997,-0.021359166000000002,-1.159161857,-0.023862402999999997,-0.043594107,-0.020396161,0.215558843,-0.057574732,-0.07513224,-0.005845456999999999,0.054822983,-0.073462555,0.030744224,-0.878205035,-1.440118679,1.015772328,1.4373404509999999,-9.044889124,-9.681272629,-9.217082642000001,-9.704488426000001,-7.416704666,-9.204897255,-7.12170323,-4.546142434,-1453.4026573118754 -328,328,R41I,0.051475337999999995,0.056238444000000005,0.07226571,0.015032337,-0.608879904,-0.080332022,0.044943208,0.058007467,0.066192163,0.017147786,0.095329102,0.02071762,0.12381379999999999,0.029124832000000003,0.000939842,-0.382953871,-0.834805937,0.684508662,1.4789609119999998,-7.823989711,-8.081413071,-8.274350647,-9.372880371,-5.779226883,-7.612077583,-6.078301101,-3.407516335,-1450.6469850013964 -329,329,R41H,0.024153756000000002,0.007820113,0.030577838,0.025247472000000003,0.021122042,-0.042750288,0.033308045,0.014999466999999999,-0.0014525470000000002,0.020375901000000002,-0.004735675,0.07769440400000001,-0.016538728,0.023690037999999997,0.026804905,0.032541371,0.009702711999999999,1.33983753,2.954958155,-4.14439126,-4.866262558,-4.056394279,-4.957537155,-3.7322924580000003,-3.109469849,-5.080128381000001,-2.8438455460000003,-1450.4238886013627 -330,330,R41K,0.07174505099999999,0.129526415,-0.065812197,-0.092824461,-0.157427045,-0.15066343,0.014729743,0.128760359,0.186418552,0.075180687,0.183872142,0.020970632,-0.152595025,-0.20934360300000002,0.023694682,-0.008119517,-0.306734572,1.304766772,2.428468314,-4.021878603999999,-4.007838219,-3.941798958,-5.133931519,-3.0674591980000003,-3.958365128,-3.127525866,-1.831786823,-1452.4387596920133 -331,331,R41M,-0.042544174000000004,0.050165097,0.046365118,-0.019561203,-0.282237032,-0.267229854,-0.05925031,-0.025838037,-0.165445685,0.043144455,0.057185739000000006,0.121949007,-0.029218772,0.036169064,-0.075291469,-0.156783747,-0.407690316,1.209663148,2.069648807,-9.12365246,-9.249342278,-9.344493996,-10.27675532,-7.339047104,-9.408623604,-7.491713806,-5.155772824,-1455.258566130884 -332,332,R41L,0.028565672,0.012327097,0.000829758,0.009176213,-0.342520526,-0.022229294,0.048534741,0.008596603000000001,0.022134968999999997,0.02566173,-0.001007536,0.020678276000000002,-0.01901876,0.013369368000000001,0.004983057,-0.28509362899999996,-0.39994742200000005,1.043328142,1.7371251269999999,-7.594377237000001,-7.865121718999999,-8.056239372,-8.804315979,-5.399986244,-7.84622287,-6.203619382,-3.71831129,-1451.532735974528 -333,333,R41N,0.045318359,0.041106422000000004,0.05293636400000001,-0.001832782,-0.225044473,-0.028365495,0.046641428,0.04399529,-0.050198333,0.024554901,0.057657942999999996,0.005892296,0.099980431,-0.009939939,0.006274376,-0.205555551,-0.244533394,1.354411976,2.0717306559999997,-7.147413536,-8.834672752000001,-6.638065598,-8.063551537,-6.002389236,-6.198388557,-6.067181409,-2.957229038,-1446.5413404535502 -334,334,R41Q,0.079704802,-0.032338335,-0.004277411,-0.009874873000000001,-0.280324444,-0.02242655,0.128997316,0.030412288,0.079645356,-0.130581243,0.06590457400000001,-0.005870749000000001,-0.002684073,-0.094267144,0.074517398,-0.291964603,-0.268684284,1.725405224,2.2882589490000003,-5.176583997,-6.3755518879999995,-5.0122434160000005,-5.651072571,-4.208332008,-4.6357200999999995,-5.491668112,-2.406481727,-1447.8879917343147 -335,335,R41P,-0.005156844,-0.013415779,0.004111325999999999,-0.0033494809999999996,-0.09971374300000001,-0.042323383,-0.002951166,-0.0073625209999999995,-0.018683797,0.002332838,-0.029164396000000002,0.031672386000000004,-0.023449735,0.025787402999999997,-0.032486364,-0.071686803,-0.127740683,1.4339148080000002,2.585515661,-8.540180766,-8.880432442,-8.313068787,-8.920650367999999,-7.153762436,-9.4329898,-7.461681698,-4.917740662,-1444.39132568473 -336,336,R41S,-0.010113505,0.02803689,0.017323919,0.017152012,-0.309092945,-0.028761482999999997,0.007218868000000001,-0.027445877999999996,0.049795038,0.045346295999999994,0.010727483000000001,0.038479689,-0.003831852,0.053735448,-0.019431425,-0.20949095399999998,-0.408694936,1.1776558609999999,1.9720012530000002,-6.728092082000001,-7.885393700000001,-6.289473663,-6.690786934,-5.698657974,-7.07614814,-5.612795017000001,-2.758965204,-1446.1248474889435 -337,337,R41T,0.005292563,-0.010290918000000001,0.030309218,-0.037575382000000004,-0.286286649,-0.018796609,0.020895518000000002,-0.010310393000000001,0.04570781,-0.02191123,0.001329394,0.04627892,0.014339515,-0.024637909,-0.050512854,-0.22418722300000002,-0.348386074,1.320921124,1.996132372,-5.357786441,-6.790398979,-4.410879402,-5.857380142,-3.788015831,-5.942257851,-4.363698391000001,-1.135423417,-1444.152709252201 -338,338,R41W,0.123407561,-0.15404347300000001,-0.08580555699999999,-0.11465087800000001,-2.024107135,-0.07270929,0.06957841099999999,0.17723671100000002,-0.010752571,-0.207319507,-0.100767438,-0.128214092,-0.043397020999999994,-0.202713025,-0.02658873,-2.103236012,-1.9449782569999998,1.2796429329999999,1.31631113,-9.193398578,-10.30094853,-9.016841087000001,-9.764631873999999,-8.5371091,-8.347462296,-8.291228436,-6.660180437,-1459.4015689231455 -339,339,R41V,-0.046817501,0.004022583,0.020972942999999997,0.011967721,-0.49186862299999995,-0.000111315,-0.044483977,-0.049151024,0.049013095,0.010506042,-0.002460877,0.043824623,-0.0018787379999999998,0.06606677799999999,-0.042131336,-0.307287876,-0.67644937,0.8938577440000001,1.61357601,-6.939408635,-7.161310951,-7.2247063979999995,-8.14816021,-5.267458839,-6.895406776000001,-5.922715871,-2.604440072,-1447.6934150285088 -340,340,R41Y,0.030734586,0.03998636,0.031102226,0.04914011,-0.608998027,-0.007637756,0.032034601,0.02943457,0.010842043,-0.021172895,0.101145615,0.04225349900000001,0.019950953,0.037836224,0.06044399599999999,-0.501176021,-0.716820033,0.57128907,1.4084087090000001,-8.450557805,-8.96179113,-9.236753685,-9.369793518,-7.415555893,-7.268894798,-6.553774327,-5.110849356,-1451.641817488242 -341,341,V42A,-0.048834558,-0.054367770999999995,-0.020670072,-0.066569947,-1.919095692,0.0010269839999999999,-0.075822649,-0.021846467,0.037153859,-0.067905561,-0.04082998,-0.034508999,-0.006831145,-0.00888129,-0.12425860400000001,-1.7661121169999998,-2.072079266,0.754085873,1.310172393,-5.750713779,-5.368870941,-4.9861660080000005,-5.493981498999999,-4.625452965,-8.279097481,-5.589696845,-1.6665650859999999,-1469.272377816029 -342,342,V42C,-0.016306958,-0.010139181,0.027446027,-0.022494841,-1.543953069,-0.11035763900000001,-0.09253013199999999,0.059916217,0.056092172,-0.067245685,0.046967324000000005,0.01205723,0.042834824,0.074412597,-0.119402279,-1.7239684769999999,-1.363937661,0.717562409,1.310414273,-11.24883848,-10.287272300000001,-11.55317311,-12.45897812,-9.921269752999999,-12.02349913,-8.131286207,-4.247702166,-1459.0759244891815 -343,343,V42E,-0.11745233199999999,-1.014123925,-2.4105924219999997,-2.697324166,-2.394525721,0.06726708099999999,-0.122491932,-0.11241273199999999,-0.04302231,-0.927745342,-1.100502508,-2.444708228,-2.376476615,-2.5014358530000003,-2.893212478,-2.256454649,-2.532596793,0.57738801,-0.603679795,-13.28097255,-12.11638589,-12.71482513,-13.80879637,-11.11338464,-16.6514707,-9.730004057,-6.711900429,-1467.210194757674 -344,344,V42D,-0.127822416,-1.305537714,-2.147604355,-2.4343360990000003,-2.884112643,0.037513529,-0.125833267,-0.129811565,-0.053346499000000006,-1.2677582170000001,-1.343317211,-2.123075422,-2.172133287,-1.878773051,-2.9898991460000004,-2.837911829,-2.9303134560000004,3.527073422,1.2370576340000001,-14.22170071,-12.82961925,-13.59708347,-15.42674113,-11.75541148,-17.4996482,-9.590015922000001,-6.711900429,-1467.7997439089231 -345,345,V42G,-0.073093496,-0.251672928,-1.4634803159999998,-2.0787464940000002,-1.921353464,-0.0045799379999999995,-0.069322555,-0.07686443700000001,-0.025710458,-0.15724022699999998,-0.34610562899999997,-1.536847106,-1.390113525,-2.420574549,-1.736918438,-2.622751376,-1.219955552,1.0123225040000001,0.05798549099999999,-12.13901232,-11.28409974,-12.17010969,-13.26162738,-9.293472969,-14.68575185,-7.179026853,-1.3593856819999999,-1467.2610152158886 -346,346,V42F,-0.109596985,-0.152504425,-0.059699559000000006,-0.097575803,-0.057509392,-0.031474665,-0.16458882800000002,-0.054605142,-0.062326592,-0.227243782,-0.07776506700000001,-0.026609581,-0.09278953599999999,-0.060107365,-0.135044241,-0.104991159,-0.010027625,1.355218569,2.2860847719999997,-8.167220334,-6.880758537,-8.669246216,-9.637797974,-8.584950974,-7.063347969,-5.451060126000001,-1.854021945,-1458.825191102922 -347,347,V42I,-0.008769621,-0.041817101,-0.059958037,-0.089884691,-0.201484743,-0.113389739,-0.091190361,0.073651119,0.060683167999999996,-0.0945148,0.010880598,-0.099594326,-0.020321747,-0.042378597999999996,-0.13739078300000002,-0.180962278,-0.222007208,1.5954643919999998,2.286032838,-1.45597131,-1.2991952359999999,-1.8273705830000002,-0.7286336520000001,-2.2808714219999997,-1.14378566,-2.7092951430000003,-0.430015489,-1463.8523843362927 -348,348,V42H,-0.095633241,-0.077905631,-0.662117764,-2.0259092709999997,-2.563731445,-0.032851672,-0.134606227,-0.056660255,0.050092344000000004,-0.11033037300000001,-0.045480889000000004,-0.54762758,-0.776607948,-1.789991781,-2.26182676,-2.402343074,-2.7251198160000003,1.847976124,0.864868008,-14.14067017,-13.313238199999999,-12.76463396,-15.27925266,-11.57984059,-17.76638544,-8.762214041,-5.51012779,-1460.0414498392493 -349,349,V42K,-0.076907735,-1.086399835,-2.316118179,-2.452334925,-2.601081474,-0.076715539,-0.112720561,-0.041094909,-0.002590601,-0.9820926209999999,-1.190707048,-2.186744502,-2.445491856,-2.243472126,-2.661197724,-2.6005509140000003,-2.601612034,0.5846008420000001,-0.61795067,-12.3862076,-11.57915673,-10.83522979,-12.07693784,-10.42470998,-17.01500368,-8.226119872,-4.937671666,-1461.7533149519004 -350,350,V42M,-0.08518411199999999,0.025537307999999998,0.013050768,-0.0322342,-0.099695113,-0.044139457,-0.117065315,-0.053302909,0.041422846,0.07224185799999999,-0.021167243,-0.011886325,0.037987861,0.02924951,-0.09371791,-0.06458784299999999,-0.134802382,1.2787204159999999,2.428647026,-8.580666524,-6.122465477,-8.733184319,-8.781018852,-9.204126373,-10.062537599999999,-6.257280428,-3.2321210469999997,-1467.3463038187474 -351,351,V42L,-0.073064142,-0.07159737599999999,-0.06822167700000001,-0.056173158,-0.143120966,-0.09379791300000001,-0.119408857,-0.026719426,0.039146222,-0.057165336,-0.086029415,-0.037557869,-0.09888548400000001,0.02185562,-0.134201936,-0.095157714,-0.191084217,1.210472728,2.210855545,-5.410240579,-2.8762259219999997,-5.385057892000001,-5.770379646,-6.67588121,-6.3436582260000005,-4.820620695,0.251478343,-1465.4067095592618 -352,352,V42N,-0.021236026,-0.029316436,-0.127444829,-1.244736528,-2.725804065,-0.044934684,-0.036450231,-0.00602182,0.047244802,-0.09392831199999999,0.035295441000000004,-0.17147539399999998,-0.083414264,-0.7320585270000001,-1.757414529,-2.7123866039999998,-2.739221525,1.250531157,0.9559068190000001,-13.83500946,-12.65718384,-14.47535558,-14.17697746,-10.85414404,-17.01138639,-8.415453989,-4.527639932,-1463.531639419496 -353,353,V42Q,-0.138643744,-0.297253804,-1.7020567290000002,-2.659999813,-2.720700732,0.014348893,-0.166878043,-0.11040944400000001,-0.041392685,-0.21220446699999998,-0.382303141,-1.4714584080000002,-1.932655049,-2.268548722,-3.0514509039999997,-2.44953625,-2.9918652139999997,1.250958046,0.116424931,-12.44468009,-10.96726592,-11.74995643,-12.20772287,-10.64473772,-16.65371751,-8.487173463,-5.157868608,-1462.2998705161735 -354,354,V42P,-0.074100851,-1.4501134530000002,-2.103837742,-2.3806974569999997,-3.3304740010000002,-0.017304509,-0.106523379,-0.041678322000000004,-0.032663874,-1.440946745,-1.459280161,-2.135852895,-2.071822589,-2.220609243,-2.540785671,-2.79953678,-3.861411222,-0.035027696000000004,-0.897457807,-11.63433995,-11.34192043,-10.60614514,-11.55235542,-10.25729943,-14.41397932,-7.41640401,-2.364376123,-1461.4331897441298 -355,355,V42S,-0.11661343,-0.080188993,-0.301495143,-1.842300377,-2.10528659,-0.00048112199999999995,-0.148309415,-0.08491744400000001,-0.079401868,-0.066693012,-0.093684974,-0.30012769300000003,-0.302862592,-1.4376785109999999,-2.2469222419999997,-2.0579987330000002,-2.152574446,2.796002436,1.7991317869999999,-10.11553294,-9.464000038,-9.996746544,-10.66503382,-8.015808113,-12.436076199999999,-7.245395211,-3.894109901,-1463.9912766297348 -356,356,V42R,-0.064301108,-1.301568907,-2.06483162,-2.2058210259999997,-2.5417970309999998,0.00557498,-0.09815975199999999,-0.030442463,-0.041392685,-1.365721917,-1.237415896,-2.044947863,-2.0847153769999998,-2.226614224,-2.185027827,-3.0608142660000004,-2.022779795,0.22643203399999998,-0.811148775,-13.38400421,-11.10321332,-12.44210976,-13.50770814,-10.85702736,-19.00996249,-8.845569055,-6.055786782999999,-1457.0402508503757 -357,357,V42T,-0.076838235,-0.047996937999999996,-0.03088769,-0.05184063,-1.804800391,0.000422425,-0.093293286,-0.060383184000000006,0.171710638,-0.049903320999999994,-0.046090554000000006,-0.039315214,-0.022460166,0.015879105,-0.119560364,-1.556925347,-2.052675435,0.638661461,1.315258182,-8.216012994,-8.130946434,-7.172704544,-8.420498749,-6.613806557,-10.74210869,-6.494612137000001,-2.4126573319999998,-1464.3805389897898 -358,358,V42W,-0.037367618,-0.062087257,-0.012738049,-0.029497987000000003,-0.7480410390000001,-0.077508068,-0.106629469,0.031894233,0.190215902,-0.027850112000000003,-0.09632440099999999,-0.034456157,0.008980059,0.035281475,-0.09427744800000001,-0.6093248379999999,-0.886757239,0.691407063,1.4091411090000001,-12.54632902,-11.01480553,-11.77137137,-13.93374648,-11.03126887,-14.98045285,-7.133334924,-2.915912394,-1458.3482672586106 -359,359,V42Y,-0.10023045300000001,-0.083763121,-0.140420345,-0.112904749,-1.576655735,-0.05267585599999999,-0.156794085,-0.04366682,-0.02208753,-0.041996570999999996,-0.125529671,-0.12237496099999999,-0.158465729,0.10031626199999999,-0.32612576,-1.946958606,-1.206352864,0.545766663,1.295458651,-11.60412526,-11.02745354,-11.49822708,-13.49940833,-10.31264599,-11.68289134,-7.77055538,-1.747340932,-1455.3772280928679 -360,360,G43A,-0.010556268,0.018114292,-0.01299378,-0.027215972,-1.171754763,-0.019636857,-0.004146897,-0.016965638999999998,-0.042451105,-0.033158722,0.069387306,-0.024616205,-0.001371355,-0.045120507000000004,-0.009311436999999999,-0.8256540659999999,-1.517855459,1.19388807,1.5105627069999998,-8.305482494,-8.844026169,-7.229489586000001,-9.348851646,-9.032743431,-7.072301636000001,-5.308879032,-2.424908077,-1446.5785805159248 -361,361,G43C,-0.079963376,0.005204986,-0.556814425,-1.7950161119999999,-2.6954737860000004,0.067136271,-0.061502195,-0.098424557,-0.028688526000000002,-0.022773292,0.033183264,-0.37713037200000005,-0.736498477,-1.494415988,-2.095616235,-2.367148769,-3.023798802,1.64219998,0.885153842,-10.22108136,-11.22729279,-8.533606812,-10.73346894,-9.758839691,-10.85219858,-6.64903826,-4.61918005,-1454.5343729453161 -362,362,G43E,-0.063096545,-1.523835756,-2.3057385530000003,-2.228948903,-2.814362219,0.023195865,-0.051892533,-0.074300557,-0.104480941,-1.374654321,-1.67301719,-2.189533394,-2.421943711,-1.984599716,-2.47329809,-2.431363764,-3.1973606739999996,0.29382053399999997,-0.8577233340000001,-13.75971575,-14.16470794,-13.16658147,-14.91205823,-12.94175538,-13.61347571,-8.138438834,-6.28505637,-1451.9094488420524 -363,363,G43D,-0.035579313,-1.308985898,-2.552514988,-2.32521034,-2.7345323969999997,-0.019801497,-0.023699283999999998,-0.047459342,-0.163089127,-1.48983322,-1.128138576,-2.55335422,-2.551675755,-1.9504805330000001,-2.699940147,-2.443002072,-3.026062722,0.24883133699999999,-1.063040398,-15.17983752,-15.56843794,-15.6326565,-15.58917384,-14.22829707,-14.88062227,-10.41556539,-10.13728232,-1454.3128085797653 -364,364,G43F,0.008573815,-0.8487223,-2.2520415480000002,-2.675251899,-2.973649581,0.088505553,0.032188896,-0.015041266999999999,0.08295567200000001,-0.71298812,-0.98445648,-2.280613864,-2.223469232,-2.376710181,-2.973793616,-2.9484129660000002,-2.9988861960000004,0.374740526,-0.553456275,-15.1100951,-16.72568621,-15.84018517,-15.40007823,-13.21064915,-14.37387673,-7.646789435,-4.426916876,-1457.4243413787335 -365,365,G43I,-0.016930748,-1.3014201440000002,-1.757612138,-2.442261861,-2.97922017,-0.015234464,-0.022679447000000002,-0.011182049,-0.14729486,-1.3540365559999998,-1.248803731,-1.6557967219999998,-1.8594275530000002,-2.177861771,-2.70666195,-2.925655815,-3.032784525,3.3530229080000002,1.148274499,-17.55281205,-18.06876511,-18.82870093,-18.24917424,-15.515943799999999,-17.10147619,-10.47188074,-10.31466836,-1450.7564926943742 -366,366,G43H,-0.017279964,-1.446754015,-2.094197529,-2.3378969069999997,-2.9373245860000003,0.032580747,0.008006810999999999,-0.042566739000000006,-0.15624970300000002,-1.255750014,-1.637758016,-2.1830512669999997,-2.00534379,-2.279147584,-2.39664623,-2.8508503689999998,-3.023798802,0.743142448,-0.725932108,-13.6477212,-15.38191731,-14.16540439,-13.30923399,-12.44064476,-12.94140556,-7.236583262000001,-4.60622181,-1456.3174944566563 -367,367,G43K,-0.081894555,-1.5271984269999999,-2.361468899,-2.483649254,-3.171122562,-0.012630415,-0.045896812,-0.117892297,-0.052638585999999994,-1.310823958,-1.7435728959999999,-2.230438382,-2.492499416,-2.201595963,-2.765702545,-3.074328743,-3.26791638,0.471716662,-0.7914996999999999,-14.73169277,-15.993635500000002,-14.43238011,-15.44536844,-13.76628203,-14.02079778,-8.359684763999999,-6.499039112,-1461.8543417262845 -368,368,G43M,0.013589131,-1.224458034,-2.278992232,-2.401172587,-3.0261765260000004,0.017405336,0.0464152,-0.019236938999999998,-0.082752623,-1.1320756,-1.316840467,-2.294728073,-2.263256391,-2.5669156490000002,-2.235429524,-2.837588438,-3.2147646130000003,0.64600267,-0.6805446620000001,-15.70775851,-16.42395145,-16.03231233,-18.06882285,-13.71296685,-14.30073907,-9.130346524,-7.189066379,-1457.3407714297064 -369,369,G43L,-0.054140074,-1.212846133,-2.325670353,-2.7372657819999997,-3.5752540880000003,0.001630185,-0.041433008,-0.06684714,-0.108203337,-1.1040181009999999,-1.321674164,-2.27668357,-2.374657135,-2.31478794,-3.159743624,-3.488550717,-3.661957459,0.7119399609999999,-0.655279386,-16.25556056,-16.9073942,-16.38049994,-17.86799541,-14.43660992,-15.68530334,-8.650885915,-6.3501416289999995,-1451.5346507378854 -370,370,G43N,-0.036299714,-1.39928115,-2.081234563,-2.675656253,-2.934463313,0.006664864,-0.018961927,-0.053637501,-0.166814064,-1.632810823,-1.165751477,-2.427486511,-1.734982614,-2.8246128230000003,-2.526699682,-2.618164358,-3.250762267,-0.07679628,-1.106848059,-13.86738216,-15.78238918,-13.52849535,-13.71421355,-12.11440718,-14.19740553,-8.326077533,-6.143917468,-1452.7360370038077 -371,371,G43Q,-0.041755758,-1.234980317,-2.2598845340000002,-2.683094885,-2.981492567,0.020733279,-0.035094436,-0.04841708,-0.140367317,-1.288750274,-1.181210359,-1.9150215309999998,-2.6047475369999997,-2.61317784,-2.753011929,-2.883850629,-3.079134505,2.430715184,0.18473790399999998,-13.73389587,-14.81988088,-13.49472028,-14.32991122,-12.37068157,-13.65428542,-7.841259302999999,-5.190785441,-1452.7520990138873 -372,372,G43P,-0.032452791,-1.572854555,-2.1320325430000002,-2.520256271,-3.0906879760000003,-0.004283567,-0.029746622,-0.035158959,-0.11638915400000001,-1.5801126540000001,-1.565596456,-2.131750293,-2.132314792,-2.424141255,-2.616371286,-2.761760834,-3.4196151169999998,-0.019045775,-1.037995266,-15.60811012,-16.21856866,-15.28665533,-16.39593468,-14.96997552,-15.16941643,-10.47188074,-10.31466851,-1462.4029591525905 -373,373,G43S,-0.013414771,0.031663285,-0.0031158,-0.023933613,-1.823495968,-0.046129330999999996,-0.022707835,-0.004121706,-0.01117313,-0.007488021,0.07081459,-0.032337035,0.026105435,-0.023249118,-0.024618107,-1.4924380130000001,-2.154553923,0.92565475,1.340169118,-8.99387086,-10.34149201,-7.51783535,-9.397020957999999,-7.875210609,-9.837795372,-5.910335861,-1.999869568,-1435.2684940099716 -374,374,G43R,-0.01653941,-1.573510556,-2.240215478,-2.4275627159999997,-2.774415405,0.005823463,0.009177201,-0.04225602,-0.13932815099999998,-1.582519915,-1.5645011969999998,-2.069216747,-2.411214208,-2.517495582,-2.33762985,-2.7881683710000003,-2.760662439,0.043870567,-1.047244703,-13.05476638,-14.41069417,-13.30337405,-13.63183779,-12.33035453,-11.59757134,-7.166468377,-4.238394326,-1457.4939926373772 -375,375,G43T,-0.042480480999999994,-0.214801142,-1.5697048040000001,-2.226703123,-3.294010353,0.01581254,-0.022802656,-0.062158305999999997,-0.081870518,-0.170295825,-0.259306459,-1.4595457040000002,-1.679863904,-2.333793272,-2.1196129740000003,-3.0815873160000002,-3.50643339,1.1424382770000001,0.09507272800000001,-11.98996554,-13.17248901,-11.64800413,-12.87892946,-10.67888241,-11.57152271,-7.154128703,-4.912868137,-1440.8726980355568 -376,376,G43W,-0.017646738999999998,-1.2828923970000001,-2.472765099,-2.168009471,-2.926816531,0.0464377,-0.021616775,-0.013676703,-0.091447217,-1.145597199,-1.4201875940000002,-2.7386275230000003,-2.206902675,-2.135753835,-2.200265107,-2.628275374,-3.225357687,0.5376087070000001,-0.705191738,-15.02642581,-14.361181099999998,-15.04275898,-16.04705257,-14.3695112,-15.311625199999998,-7.375283427,-3.516243648,-1459.1530507900752 -377,377,G43V,-0.045673358,-1.25684123,-2.068467838,-2.51237453,-2.921696588,-0.007825116,-0.041632157999999996,-0.049714557,-0.096451403,-1.232059266,-1.281623194,-2.009475948,-2.1274597269999997,-2.14696495,-2.87778411,-2.338456494,-3.504936681,3.884151605,1.615616804,-15.79596283,-16.1755331,-16.91849915,-17.07108961,-14.5564424,-14.25824988,-9.053022883999999,-7.123456681,-1450.501152312383 -378,378,G43Y,-0.00396217,-0.968048925,-2.584198589,-2.467818316,-3.092822255,-0.036679704,0.034221808,-0.042146147,-0.055376793,-0.71168197,-1.22441588,-2.157266216,-3.011130961,-2.2533625330000002,-2.682274098,-3.0011565769999997,-3.184487933,0.9541846979999999,-0.44063281200000004,-15.93702095,-17.3521134,-16.64099828,-15.51975657,-13.93598613,-16.23625039,-8.09764078,-5.990049015,-1451.9194968487136 -379,379,Y44A,-0.032056769,-0.037020995,-0.71736319,-1.9912570319999998,-2.982065641,0.065134491,-0.00799999,-0.056113548,-0.077073734,-0.063749276,-0.010292713,-0.40173626100000004,-1.0329901190000002,-1.859973752,-2.122540311,-2.528732496,-3.4353987860000004,1.582342897,0.76753041,-5.200916205,-6.367536705,-6.534333022999999,-3.1685770110000004,-4.196208145,-5.73792614,-4.030029364,1.261619069,-1463.4033198733814 -380,380,Y44C,0.005731835,-0.027246875,-0.9634012190000001,-2.117774895,-3.081494016,0.056076272,0.064422019,-0.052958349,-0.032848122,-0.025188492000000003,-0.029305257,-0.845412157,-1.081390281,-2.083577156,-2.1519726340000003,-2.788333553,-3.374654478,1.958907606,0.771965128,-7.681247687000001,-7.874620437999999,-8.790595512000001,-5.928133461,-7.69243821,-8.120450813,-6.742638616,-2.284247111,-1458.270628969185 -381,381,Y44E,-0.031477692,-0.354135011,-1.616983297,-2.625848473,-2.9701265489999997,0.08393912,0.001397176,-0.06435256,-0.020314853,-0.248172896,-0.460097126,-1.5219090419999999,-1.712057551,-2.6261804619999998,-2.6255164840000003,-2.904968127,-3.0352849710000003,1.235635815,0.093376852,-10.07004825,-10.2249962,-10.88807263,-8.534778046,-9.787725784,-10.91466857,-8.720518431,-6.437688822,-1469.6501502972096 -382,382,Y44D,0.00851447,-1.465348139,-1.960738831,-2.202047407,-2.5692042280000003,0.055964627999999995,0.02364877,-0.00661983,-0.16702916199999998,-1.580020821,-1.350675457,-1.776995195,-2.144482466,-2.279206624,-2.124888189,-2.381903029,-2.7565054260000004,0.43335027600000003,-0.9775392940000001,-10.53742591,-10.31608683,-11.64558296,-8.708262283,-10.31205057,-11.705146899999999,-8.720518431,-6.437688822,-1465.9328439668752 -383,383,Y44G,-0.00615611,-0.061174353,-1.161942904,-2.310945467,-3.025105581,0.059040801,0.032595772,-0.044907992,-0.065655589,-0.018007045,-0.10434166,-0.92454909,-1.399336717,-2.180428675,-2.441462259,-2.8157636630000002,-3.234447498,1.920225155,0.699607688,-9.475370552000001,-9.335515411,-10.88684491,-7.60013411,-8.74976976,-10.80458857,-7.070268662999999,-2.45768412,-1455.9923848966137 -384,384,Y44F,0.041897981,0.020924838,-0.016223451,-0.0007790710000000001,-0.040809435,-0.013767383999999999,0.048343202,0.035452759,-0.010164613000000001,0.014771703999999998,0.027077971,-0.035604872999999995,0.003157972,-0.07259427,0.071036128,-0.082826713,0.0012078430000000001,1.38895447,2.334282891,-1.9301683490000001,-2.346116386,-2.2898701630000002,-1.70944101,-2.037169846,-1.268244339,-3.87037683,1.3696913730000002,-1463.3833870026283 -385,385,Y44I,0.016883048,0.012810142,0.02749229,-0.001490999,-1.736939019,-0.0023480379999999998,0.050895873,-0.017129778000000002,-0.093440265,0.010239244,0.01538104,-0.012992684,0.06797726400000001,-0.086359831,0.083377834,-1.452297671,-2.021580367,0.947951862,1.346617629,-3.4261277010000004,-2.943506485,-2.2357930219999997,-4.714617218,-4.828631165,-2.4080906140000002,-3.6482122739999996,2.387929523,-1463.0531122465618 -386,386,Y44H,0.040203334,-0.039072077999999996,0.007924563,-1.334261128,-2.831751718,0.074008604,0.039131736,0.041274931,-0.08105776,-0.066393272,-0.011750884,-0.041518897,0.057368023,-1.064818163,-1.6037040930000002,-2.297848337,-3.3656550989999996,0.795958919,0.75204432,-6.9893592479999995,-5.931827782,-7.976832047,-6.169763466,-7.36584169,-7.502531257999999,-7.8344044770000005,-3.864455032,-1466.8848403282464 -387,387,Y44K,-0.056311569000000006,-1.557521102,-2.2006248530000003,-2.732368775,-3.16469248,0.061873015999999996,-0.028566047999999997,-0.08405709,-0.179864649,-1.672673845,-1.442368359,-2.2120709,-2.189178805,-2.8392210660000003,-2.6255164840000003,-3.11800873,-3.21137623,0.024296011,-1.115461198,-9.736752542,-9.470126595,-10.69543957,-8.567718597,-10.05385624,-9.896621712,-8.713237982999999,-6.416687425,-1472.5862756771967 -388,388,Y44M,0.042024964000000005,0.055788355,0.024222335,0.019593148,-0.283943015,0.050952017999999995,0.054180662000000004,0.029869265,-0.055681864000000005,0.030461143,0.081115566,-0.034245929,0.082690599,-0.068737256,0.10792355099999999,-0.222254788,-0.345631242,1.329867247,1.9861046690000002,-4.1835767530000005,-3.574339935,-4.386810173,-4.112641281,-4.3667755360000005,-4.477316841,-3.7628866039999997,0.27847269199999997,-1468.0950885298662 -389,389,Y44L,0.014614007,-0.020088335,-0.0046129909999999994,-0.045606460999999994,-0.24651114899999998,0.055245175,0.024009124,0.00521889,0.00594241,-0.047784756,0.007608086,-0.068293069,0.059067087000000004,-0.11132820199999999,0.02011528,-0.211479175,-0.281543123,1.580177299,2.202133025,-4.056317366,-2.6581797330000003,-5.504900871,-3.603613213,-5.5493615489999994,-2.9655314639999997,-3.2905292360000002,2.2564483109999998,-1467.445704436861 -390,390,Y44N,-0.077406009,-1.325477936,-1.981978275,-2.6977105889999997,-3.041988665,0.136324993,0.019294213,-0.17410623100000003,-0.16184442,-1.312239304,-1.338716567,-2.100278286,-1.8636782630000002,-2.250307196,-3.145113981,-2.8301248560000003,-3.2538524730000002,0.7872898979999999,-0.771315304,-9.665858127,-9.29325222,-10.73499046,-7.657531677000001,-9.69152581,-10.95199046,-8.720518431,-6.437688822,-1465.1977570373565 -391,391,Y44Q,0.018710097,-0.672057076,-2.272106267,-2.375183941,-3.196583271,0.10302207599999999,0.041143334,-0.00372314,-0.097845943,-0.443399166,-0.900714985,-2.194256567,-2.349955967,-2.520376736,-2.229991145,-3.100194396,-3.2929721460000003,1.0043388340000001,-0.291659593,-10.05262725,-9.848283775,-11.14612659,-8.755823814,-10.58069165,-9.932210426000001,-8.720518431,-6.437688822,-1471.5513148270547 -392,392,Y44P,0.026203387,-1.250192171,-2.226162408,-2.457348907,-3.027775819,0.070421711,0.050966606,0.001440167,-0.09418660400000001,-1.259382979,-1.241001362,-2.255697903,-2.1966269119999997,-2.451484304,-2.463213509,-2.730271969,-3.3252796680000003,0.578847252,-0.767887358,-10.72467361,-10.64210197,-11.66295556,-9.186104178999999,-10.39554406,-11.73666228,-8.720518431,-6.437688822,-1468.0284522837028 -393,393,Y44S,-0.041875567999999995,-0.635703169,-2.002437547,-2.3173536880000003,-3.19008419,0.059412067,-0.003955683,-0.079795453,-0.006228569000000001,-0.391702759,-0.879703578,-2.040901808,-1.963973285,-2.058305153,-2.576402223,-2.6158464180000003,-3.7643219610000003,1.123315956,-0.164079843,-8.318059821,-8.327958054,-9.576047096,-5.526725151,-8.026759277,-10.13280952,-6.719616942999999,-2.5063604980000003,-1463.564619267825 -394,394,Y44R,0.006585203,-1.275479135,-2.187369786,-2.772341373,-3.025154107,0.057826750999999996,0.035027897,-0.021857492000000003,-0.11510937800000001,-1.236736405,-1.314221865,-2.137616001,-2.23712357,-2.5886749069999997,-2.956007838,-2.809470625,-3.240837589,0.534335731,-0.737128415,-9.548428354,-9.168073212000001,-11.27351493,-8.795771126,-9.921830948,-8.582951553,-7.990917005,-3.864455032,-1469.0202169483528 -395,395,Y44T,-0.01399395,-0.066186724,-1.320752277,-2.179884405,-3.195373822,0.012717504,0.020645322,-0.048633221,-0.04274268,-0.045031645,-0.08734180300000001,-1.105717908,-1.535786645,-2.13900256,-2.22076625,-2.71882022,-3.671927423,2.147963049,0.7840983,-8.034178277999999,-7.59798037,-8.88224559,-7.274069183,-8.135916557,-8.280679688,-6.15108948,-2.1478479740000003,-1465.2577559165657 -396,396,Y44W,0.005107688,0.017237439,-0.127504811,-1.6054726519999998,-2.641882621,0.005950779000000001,0.038892894,-0.028677518,-0.019302853999999998,0.013024613999999999,0.021450262999999997,-0.132436891,-0.12257273,-1.376299336,-1.834645967,-2.362657177,-2.921108064,0.9783987740000001,0.744755682,-6.362318027000001,-5.899110199,-6.682725914,-5.567910034,-5.990093497999999,-7.671750488,-5.976417446,-1.8153197669999999,-1466.373742941767 -397,397,Y44V,0.014236500000000001,0.005720869,0.004887949,-0.040962159,-1.726355619,0.010963715,0.038012015,-0.009539015,-0.054385564000000004,-0.013590135,0.025031872,-0.039020877999999995,0.04879677599999999,-0.108545481,0.026621164,-1.5362221219999999,-1.916489116,0.970809488,1.341534885,-2.8672590319999998,-2.735881088,-3.6199027860000004,-3.0599272999999996,-3.667648285,-1.252935699,-2.869941874,3.738011573,-1461.914449046366 -398,398,I45A,-0.014891277,-0.010251234,-0.0036765870000000003,0.060311952,-0.09053404599999999,-0.056741781,-0.034279223,0.004496669,-0.20493012,0.028671473,-0.049173941,0.020743258,-0.028096431,0.119841818,0.0007820860000000001,0.013013657,-0.194081748,1.285342084,2.83066336,3.326653287,3.298470413,3.066868988,3.2820297089999997,2.5221527790000002,4.463744545,0.169601665,3.435507963,-1459.4116015541367 -399,399,I45C,0.007388436,0.015949234,0.032874367,0.09476568199999999,-0.20808194800000002,0.07466110599999999,0.02001589,-0.005239018,-0.292511723,0.048737224,-0.016838756,0.053882463,0.01186627,0.128877585,0.060653778,0.017845864,-0.43400976,1.1941092229999999,2.81642152,-1.855377847,-1.227930305,-1.14993161,-0.856829185,-3.5645902019999998,-2.4776079330000003,-2.716622895,0.786985002,-1459.069570706226 -400,400,I45E,-0.036329991,-0.034148793999999996,-0.020492715,-1.418600532,-2.206823683,0.014938673999999999,-0.049269905,-0.023390076,-0.181041654,-0.029511614,-0.038785974,-0.00329292,-0.03769251,-1.084728433,-1.7524726309999998,-2.273341286,-2.140306079,0.8504856670000001,0.7610655609999999,-2.5166178880000003,-1.766643425,-2.830656815,-1.186383545,-3.521043648,-3.2783620069999997,-3.896640899,-0.8963184209999999,-1466.8826036034152 -401,401,I45D,-0.034741945,-0.217495627,-1.702230135,-2.355596727,-2.744946474,0.018812048,-0.015416655,-0.054067234000000006,-0.1921813,-0.064772051,-0.370219203,-1.343972934,-2.060487336,-2.2500273999999996,-2.461166053,-2.60613134,-2.883761607,0.933372471,0.093055119,-4.010463385,-3.7072863160000002,-4.276267365,-2.925807854,-4.8816080930000005,-4.2613472980000004,-4.839185682,-2.202842813,-1467.025316373445 -402,402,I45G,-0.020888382,-0.01591693,-0.07062275400000001,-1.601799435,-2.210408061,-0.005257456,-0.024932955,-0.016843808999999998,-0.222332809,-0.016754189,-0.01507967,-0.010982448999999998,-0.13026305800000001,-1.32026252,-1.88333635,-2.2127476759999998,-2.208068446,0.851839074,0.734195582,-2.6290177630000002,-1.068601776,-2.1655221019999997,-1.70922319,-3.516324081,-4.685417664,-3.010405865,0.232191208,-1461.0879329694435 -403,403,I45F,0.036822897,0.051928422,0.050583595999999995,0.12096271800000001,0.139663466,-0.04017073,0.028710773,0.04493502,-0.24342621600000003,0.062187604,0.04166924,0.09560276699999999,0.005564425,0.21213025,0.029795185,0.21619534399999998,0.063131587,0.9142746409999999,3.018596392,-0.14109949,0.109815613,-0.628009018,0.562375031,-1.658426971,0.9087478940000001,-2.1298192240000002,2.489877843,-1456.8456211406738 -404,404,I45H,-0.045660262,-0.011967566,-0.020381376,-0.646046104,-2.169112095,-0.038642684,-0.037582444,-0.053738079,-0.22710956,0.018236766,-0.042171898,-0.005057862,-0.035704889,-0.372596983,-0.919495224,-2.026096634,-2.312127555,1.4950265740000002,1.347648512,-1.219146098,-0.9963319629999999,-1.111905502,-0.589825798,-1.88270372,-1.514963509,-2.31242183,2.063681437,-1463.4807422724552 -405,405,I45K,-0.018968267,-0.39921294399999996,-1.705642668,-2.296539891,-2.9473290110000003,-0.06968419099999999,-0.04155759999999999,0.0036210659999999996,-0.189465828,-0.22155815399999998,-0.576867734,-1.606712004,-1.804573332,-2.132555228,-2.460524554,-2.789689164,-3.1049688580000003,1.420247118,0.118345787,-3.8838373280000003,-3.301928169,-5.146250061,-2.907959015,-4.79464463,-3.268404762,-5.259645741,-2.333509679,-1464.0160575904883 -406,406,I45M,-0.004667943,0.018591503,0.007400829,0.06067423,-0.361981496,-0.051515730999999995,-0.00737908,-0.001956806,-0.20094993600000002,0.026662312,0.010520693000000001,-0.022317807000000002,0.037119465,0.10172946,0.019619,-0.17908827800000002,-0.544874714,1.252387475,2.081072839,-0.29936656300000003,-0.213972931,-1.37041983,0.296932594,-1.24780616,1.03843351,-2.962662043,-0.083641429,-1459.953613738995 -407,407,I45L,0.031797042000000005,-0.005337476999999999,0.021407197000000003,0.07363445099999999,0.108687949,-0.036477322,0.018342041,0.045252042,-0.196976609,-0.000759542,-0.009915410999999999,0.044821819000000006,-0.002007425,0.13535979,0.011909111000000002,0.226670178,-0.00929428,0.945439444,3.1116413119999997,-0.0069666630000000005,0.673880844,-0.9098845520000001,1.048926575,0.14503633900000001,-0.9927925190000001,-2.7274268839999998,1.589487343,-1459.432650083676 -408,408,I45N,-0.012980671000000001,0.018068827,-0.319156277,-1.6807976180000002,-2.632616734,0.054159132,-0.016617431000000002,-0.009343911,-0.254805187,0.047780511,-0.011642858,-0.200784378,-0.437528176,-1.544523359,-1.8170718769999998,-2.50268729,-2.762546177,1.2013852170000001,0.75273817,-3.3396847380000003,-3.2541949389999996,-3.997139877,-2.594777939,-4.193219421,-2.659091515,-4.583091233999999,-1.935760123,-1469.012795876246 -409,409,I45Q,0.000276368,-0.018293848999999997,-0.032400378,-0.04257319,-1.581182994,-0.073691823,0.003110448,-0.002557712,-0.17897961,-0.005650598000000001,-0.0309371,-0.012043273,-0.052757483,0.045161589,-0.130307968,-1.50525843,-1.657107558,0.619138335,1.316428965,-1.760384074,-1.334345718,-2.420620621,-1.102562531,-1.914016434,-2.030375069,-3.500349739,-0.649267586,-1465.7780010774732 -410,410,I45P,-0.032289778,-1.48602847,-2.227593906,-2.265296022,-2.896751736,-0.017779745,-0.029995638999999998,-0.034583916,-0.32057431399999997,-1.4651576469999998,-1.506899293,-2.134701358,-2.320486454,-2.227842467,-2.302749576,-2.74364725,-3.049856222,1.792513122,-0.5356174810000001,-4.94666398,-4.272957031,-5.355366127,-4.1307752760000005,-5.78031295,-5.1939085160000005,-6.866717857,-5.589167355,-1464.0964677087031 -411,411,I45S,-0.041614227000000004,-0.01125545,-0.001442758,0.061595782,-1.494600621,-0.011318352,-0.063262464,-0.019965989,-0.22620821,0.033593582999999996,-0.056104482000000004,0.018881702,-0.021767217000000002,0.10027640800000001,0.022915155,-1.364972001,-1.6242292409999999,0.56597735,1.318579774,1.669666541,1.7485426480000001,1.756723038,1.819228676,0.36859000399999997,2.6552483369999997,-1.295651665,2.374909329,-1464.5372839486226 -412,412,I45R,-0.044948252,-0.037685244,-0.24089141100000003,-1.657245813,-2.60881519,-0.0037643359999999996,-0.043349719,-0.046546785,-0.233237845,-0.020200821,-0.055169666,-0.10131343400000001,-0.38046938700000005,-1.402827007,-1.911664618,-2.0180687809999998,-3.1995615980000003,2.7947938789999998,1.889843638,-3.019039293,-2.85657653,-3.2746641010000004,-2.265980095,-3.4469306339999997,-3.251045105,-4.2600426360000005,-0.501861679,-1462.3596983351745 -413,413,I45T,-0.041662465,-0.053740798,-0.034064788,0.025185182999999996,-0.426357269,-0.09068389800000001,-0.063211104,-0.020113825,-0.205277131,-0.02276543,-0.084716166,-0.013306181,-0.054823394000000004,0.07156475400000001,-0.021194388999999998,-0.260009143,-0.592705394,0.9315990470000001,1.694327196,1.7490607530000002,1.5317357180000002,1.4812826769999998,1.705367249,0.835747337,3.1911707839999996,-0.817092127,0.9670311840000001,-1465.0952809802257 -414,414,I45W,-0.05570905,-0.088478575,-1.1840278,-2.140760722,-2.9109908860000004,-0.016762281,-0.072527172,-0.038890928,-0.213213255,0.017485675,-0.194442825,-1.046992535,-1.321063065,-1.699441655,-2.582079788,-2.993397688,-2.8285840839999996,2.4094699090000002,1.114131465,-3.205490727,-2.105722733,-4.057880668999999,-1.318829796,-3.7960662989999996,-4.74895414,-3.2306559939999997,0.430730935,-1455.7138345078565 -415,415,I45V,-0.004989384,-0.04281224,-0.032864557999999995,0.035339036000000004,0.12200949,-0.04214383,-0.020172717,0.010193949,-0.139570265,-0.030712117999999997,-0.054912362,-0.007965682,-0.057763432999999996,0.09887483300000001,-0.028196762,0.190229713,0.053789267,1.543610422,3.106887046,1.784145535,1.918226631,1.30478952,1.898335976,1.39562162,2.403753929,-0.609537134,1.719377433,-1462.1254714932293 -416,416,I45Y,0.031627791,0.011890158999999999,0.058367113,0.10621945,-0.198298791,-0.041183062,0.050049058,0.013206523999999999,-0.257583044,0.021708434,0.002071883,0.052640083,0.064094142,0.144879153,0.06755974599999999,0.015638868,-0.41223645,1.1060094409999999,2.723212628,-0.308281503,-0.6998122859999999,-0.7674776,0.313041862,-1.865627411,1.4784679180000002,-1.454455146,3.3589984989999997,-1456.5051797721535 -417,417,E46A,0.06054994,0.050636307,0.030166752,0.085523852,-0.05797503,0.013691409,0.091959717,0.029140162,0.154220461,0.099576909,0.001695705,-0.017796108,0.078129611,0.0461185,0.124929204,-0.111100066,-0.004849994,1.229407927,2.219399137,-3.808890753,-5.366256149,-3.003720993,-4.174555626,-4.262225418,-2.23769558,-3.642318775,4.487299911,-1452.632328234613 -418,418,E46C,-0.056629725,0.025298822999999998,-0.009662677,-0.22259505,-1.899140071,0.010692466000000001,-0.030418266,-0.082841184,0.012697907,0.08683486900000001,-0.036237224,0.00360007,-0.022925424,-0.07711414700000001,-0.36807595299999996,-1.8452071780000001,-1.953072964,0.957874186,1.315371901,-8.587476062,-8.806901161,-6.602233582,-10.14982264,-7.989672722000001,-9.388750206000001,-5.914546283,0.202951675,-1449.7114131296985 -419,419,E46D,-0.034026852,0.077207259,-0.01121432,0.066829216,-1.243973026,0.070207849,-0.0019518889999999998,-0.066101815,0.07087382099999999,0.120517982,0.033896536,0.001117862,-0.023546502,0.08425423800000001,0.049404193,-0.947091228,-1.540854824,0.18103532,1.315883854,-6.28407231,-6.306083374,-5.355953209,-5.749550033999999,-6.326615189,-7.682159744,-8.707703472999999,-5.014427893,-1461.1959652723745 -420,420,E46G,-0.0716871,0.022127314,-0.033731841,-0.112749622,-1.769257835,0.047312572000000004,-0.044943791,-0.09843040900000001,0.045381452,0.032843258,0.011411369,-0.015423167,-0.052040515,-0.080134065,-0.145365178,-1.837995065,-1.700520604,0.870913354,1.312266635,-7.88550468,-8.498576492,-6.768200195,-7.905658371,-6.715464317,-9.539624023,-5.151778062,1.027239873,-1461.1562791024335 -421,421,E46F,0.056858217999999995,0.012120928999999999,-0.005820929,0.09162494199999999,-1.180487928,-0.033962325,0.078717836,0.034998599,0.019894801,0.026016262000000002,-0.001774405,-0.034663114,0.023021257000000003,0.06675508200000001,0.116494801,-0.801037275,-1.559938581,0.479584795,1.346875254,-7.66766398,-6.2973042910000006,-6.980595253,-9.270146217,-7.842499022999999,-7.947775116,-5.086982256000001,2.794745494,-1450.7494095717557 -422,422,E46I,0.017371427,0.071263735,0.04403818599999999,0.074960336,-0.6382741820000001,0.0005886940000000001,0.011841646,0.022901208,0.01318001,0.098159972,0.044367498,0.053893439,0.034182932,0.057686429000000004,0.092234242,-0.5555714629999999,-0.7209769009999999,0.498235184,1.37936072,-4.231761859,-3.4725048289999996,-4.839422783,-3.748002609,-2.647958649,-6.450920425,-2.773764012,3.5552320319999997,-1453.0899082422256 -423,423,E46H,0.016038643,0.038763722,-0.004284774,0.070566517,-0.84199284,-0.010645621000000001,0.064702105,-0.03262482,0.020417451,0.07613890400000001,0.001388539,0.002980277,-0.011549823999999998,0.059088533,0.0820445,-0.619399754,-1.064585926,0.667201688,1.403997961,-9.856631718,-9.940475021000001,-7.892904518,-11.24007329,-11.11778837,-9.091917397000001,-7.612027349,-2.585164641,-1454.3872297825292 -424,424,E46K,-0.04262828900000001,0.009826356,-0.028252494,0.05020906,-0.22417449899999997,0.053422087,-0.029650105,-0.055606473,0.004697474,0.086771448,-0.067118736,0.000339186,-0.056844173,0.07971924,0.020698879,-0.18200102199999998,-0.26634797600000004,1.230778489,2.044033568,-7.983046542,-8.664197655,-6.375084496,-8.858606712,-7.35169342,-8.665650429,-8.665464397000001,-4.892439621,-1461.3223886806518 -425,425,E46M,0.036580697,0.059989659,-0.000607231,0.050199035,-0.019380393,0.00388934,0.035434777,0.037726616,0.063261867,0.13963688,-0.019657562,-0.00344187,0.002227409,0.022660612000000004,0.077737458,-0.01826552,-0.020495266,1.1590993840000001,2.464796203,-5.721038084,-4.642255157,-6.406587486,-6.820715187,-4.474703208999999,-6.2609293820000005,-3.5219039010000004,1.457089605,-1457.1465516611934 -426,426,E46L,-0.00807517,0.047658725,-0.002553821,0.052847915999999995,-0.114128551,-0.019832737,-0.00376702,-0.01238332,0.057383958,0.08846176900000001,0.006855681,0.001565629,-0.006673271,0.05677958,0.048916250999999994,-0.115979851,-0.112277251,1.2430237370000001,2.18724123,-4.538006567,-3.394428352,-6.556716064,-4.450208595,-3.1138764039999995,-5.174803421,-3.215730677,3.086687004,-1453.920916115865 -427,427,E46N,-0.009217056,0.05041252,-0.023756553,0.05014026,0.002957374,0.044187715999999995,0.011812086999999999,-0.030246198,0.054513575999999994,0.10628193,-0.00545689,-0.019917459,-0.027595646,0.074618377,0.025662142000000002,-0.048247827,0.054162574000000005,1.231905283,2.494125114,-8.82970883,-8.282891525,-7.528516487,-9.21359021,-8.987594482,-10.13595145,-8.707703472999999,-5.014427865,-1459.8322003176436 -428,428,E46Q,-3.929999999999999e-05,0.018893436,-0.052478897000000004,0.040676305,0.013281701000000002,-0.018003293,-0.000370539,0.000291882,0.054529875,0.04139076,-0.0036038890000000003,-0.059334277000000005,-0.045623515999999996,0.025962124,0.055390485999999996,-0.021479919,0.04804332,1.2008836840000001,2.47469079,-4.7087223719999995,-4.221145706000001,-5.062656723,-5.104541771,-3.656731575,-5.498536087000001,-6.397644746,-1.9150143069999999,-1459.5725387330167 -429,429,E46P,-0.052235465,-1.334710467,-2.157057672,-2.115757725,-2.526018257,0.024315688,-0.030253078,-0.074217852,-0.018536113,-1.321607612,-1.3478133209999998,-2.367930328,-1.946185015,-1.9740178080000002,-2.2574976419999997,-2.445535185,-2.606501329,0.17574834,-0.823624142,-10.38930708,-10.62341103,-9.37322773,-11.79142071,-10.06058698,-10.09788898,-8.513403621,-4.228818024,-1459.9822567943484 -430,430,E46S,-0.019238599,0.00025504200000000003,-0.028739924,0.057902964,-0.006555508000000001,0.038353476000000004,-0.01855298,-0.019924218,0.038079569,0.031720898,-0.031210815,-0.025830129,-0.031649718,0.043292607000000004,0.07251332099999999,-0.004788786,-0.008322229,1.153119917,2.483269178,-7.783836906,-8.225326767,-5.116671913,-9.389224083,-7.452924423,-8.735037346,-6.279417779,-0.664948268,-1458.636436948087 -431,431,E46R,-0.054496014,0.017555477,-0.015553218,-1.238927817,-2.305126814,0.036406638,-0.034105339,-0.074886689,-0.012558231999999999,0.066399326,-0.031288372,-0.017221723,-0.013884713,-0.665080744,-1.81277489,-1.869896154,-2.740357473,1.826191017,1.446219353,-8.536732475,-9.519359489,-7.328752586,-9.701802528,-8.304648407,-7.829099365,-6.68473156,-1.5227881319999998,-1458.0963610294275 -432,432,E46T,-0.03691943,0.018746185,-0.054674957999999996,0.040899157,-0.119318986,0.021289178,-0.031073002000000002,-0.042765858,0.103225619,0.062409485,-0.024917116,-0.022000142,-0.087349774,0.051597051,0.030201262000000003,-0.132083344,-0.10655462800000001,1.4371960190000002,2.35126766,-7.207790398999999,-8.462076309,-5.750165947,-7.075709122,-6.700850449,-8.050150169,-5.808738174,-0.236334988,-1457.7953046057373 -433,433,E46W,-0.025455624,0.053528052,-0.002827434,-1.371179138,-2.2824983309999998,0.024918929,0.002392595,-0.053303843,0.035329843,0.060204085,0.046852017999999995,0.0077124540000000005,-0.013367322,-0.917954226,-1.82440405,-2.159797516,-2.4051991459999997,1.98631072,1.3937407569999998,-9.813522336,-9.799028801,-9.46931176,-11.09954016,-8.457481162999999,-10.24224979,-6.396960907,-0.5495289560000001,-1454.6576681677252 -434,434,E46V,-0.026138446,0.011802706999999999,-0.021033887999999997,0.047510002,-0.37781022200000003,-0.018590215,-0.018086215,-0.034190676,0.041749152000000005,0.070934786,-0.047329372,-0.021033095,-0.021034681,0.030835808,0.064184196,-0.286296736,-0.46932370700000003,1.359013494,1.9596026119999999,-3.073412158,-3.5394050060000004,-2.898226036,-3.6137048189999996,-2.234872971,-3.080851959,-3.03236904,4.380493027,-1451.723865448963 -435,435,E46Y,-0.015178575,0.018257015,-0.036370772999999995,0.039721939,-1.06271258,-0.011632763,0.006914764,-0.037271913999999996,0.044365529,0.114175661,-0.077661631,0.0015099129999999999,-0.074251459,0.051543201,0.027900676,-0.806396308,-1.319028851,0.603182376,1.366965919,-8.818946312000001,-8.502829536,-6.69534977,-10.6518856,-8.947990135,-9.296676521,-5.901327855,1.664637617,-1449.2736015776172 -436,436,L47A,-0.051059291,0.003596347,-0.012033631000000001,0.00308627,-0.587413548,0.076982759,-0.074931998,-0.027186582999999997,-0.005942553000000001,0.019082994,-0.011890301,0.009476974,-0.033544235,0.017717286000000002,-0.011544747,-0.38660588700000004,-0.788221209,0.869335544,1.557849448,-5.976561972000001,-5.868159508,-6.0610713579999995,-6.23526918,-6.835502067999999,-4.882807747,-4.226155507,-2.330969833,-1462.679940267466 -437,437,L47C,-0.17789538300000002,-0.010264684,-0.037005878,-0.053354012,-1.7207472680000002,0.054898685999999995,-0.18166569,-0.17412507600000002,0.026060853,0.10352193300000001,-0.12405129999999999,0.049881302999999995,-0.12389305800000001,0.091714584,-0.198422608,-1.332143453,-2.109351082,0.609765311,1.323823782,-6.961350917000001,-6.905696136,-6.733259422000001,-6.973345413,-8.270936897,-5.923516716,-5.22799321,-3.692537488,-1463.3348925025202 -438,438,L47E,-0.013553505,0.035271324,0.0044990379999999995,-0.39042400200000005,-1.741683954,0.083603992,0.023627269,-0.050734278,0.0047279620000000005,0.006651574,0.063891074,0.004701454,0.004296622,-0.068516258,-0.7123317459999999,-1.5947517130000002,-1.8886161940000001,0.8047808870000001,1.324518555,-5.441822897000001,-6.168141296,-5.322952377,-5.7028271639999994,-7.913175926,-2.1020177230000003,-3.3567426019999997,-1.3200946279999999,-1466.7078264695592 -439,439,L47D,-0.051868795,-0.213851309,-1.4478525119999999,-2.276927975,-2.5184671130000003,0.073470414,-0.064013779,-0.039723811,0.008954258,-0.107920204,-0.319782413,-1.233587675,-1.6621173480000002,-2.469639117,-2.084216833,-2.271598702,-2.7653355239999997,0.974016088,0.117022543,-8.13867099,-8.341438065,-8.463430618,-8.373262749,-8.645823456,-6.869400063,-7.035237185,-3.91987831,-1469.0935986354016 -440,440,L47G,-0.11137873400000001,0.013844163999999999,-0.087146852,-1.6614188109999999,-2.8146950630000003,0.09469222199999999,-0.081204666,-0.141552802,-0.049342564000000005,0.036530436,-0.008842108000000001,0.022069126,-0.196362829,-1.4155797680000002,-1.9072578530000002,-2.484711081,-3.1446790439999996,0.816678433,0.7204311040000001,-6.813700732,-7.064935921,-6.404118187000001,-7.757251274,-7.1255508579999995,-5.7166474229999995,-5.105666458,-2.971218,-1462.827507479582 -441,441,L47F,-0.111915134,0.02702744,-0.005378514,-0.034650598,-1.674340022,0.000251126,-0.124618205,-0.09921206199999999,-0.071283237,0.032419184,0.021635695,0.046623987,-0.057381015,0.000498635,-0.06979983099999999,-1.35274265,-1.9959373930000002,0.768567621,1.335126229,-4.025596591,-3.3302421719999997,-3.85523616,-3.148200089,-6.193979256,-3.6003252789999998,-3.280946487,-2.371572923,-1459.1374522843398 -442,442,L47I,-0.00042362,-0.036014443,0.001604926,0.009014886,0.024688881,0.048821878,-0.006509568,0.005662329,-0.014162802,-0.017844302,-0.054184584,0.036526353,-0.033316502000000005,0.064395316,-0.046365545,0.08634447199999999,-0.03696671,1.06323227,2.75959641,-1.987486255,-1.6387163009999999,-2.675816452,-2.777168381,-1.885587334,-0.960142807,-2.9525854689999997,-0.535826644,-1463.1062143049203 -443,443,L47H,-0.042535027999999996,0.0034903829999999997,-0.029723903,-1.6432079430000002,-2.394776979,0.03861328,-0.059628997,-0.025441059,0.009260621,0.005599929,0.001380836,0.008416475,-0.067864281,-1.419520492,-1.8668953940000002,-2.476752583,-2.312801374,0.579052138,0.699429082,-4.68906608,-4.306247032,-5.058229225,-5.801630219,-4.84699823,-3.432225693,-3.658150931,-1.851189409,-1466.040438753087 -444,444,L47K,-0.09857844199999999,0.012938495,-0.033523903,-1.01202238,-2.002716795,0.08713804900000001,-0.064378005,-0.13277887800000002,-0.014665225,0.00739597,0.018481018999999998,-0.032426362,-0.034621444,-0.639665653,-1.3843791069999998,-2.057049191,-1.948384399,1.821381855,1.395874941,-5.093168765,-6.037705551,-4.468633415,-7.533616829,-4.685288727,-2.740599304,-5.1023377530000005,-0.8544726290000001,-1466.56680391822 -445,445,L47M,-0.030054335,-0.017289793,0.0012028339999999998,-0.00286302,0.013633703,0.00604344,-0.035179454,-0.024929216,0.031437411,-0.049824081,0.015244496000000001,0.010151387,-0.00774572,-0.003699317,-0.0020267220000000003,0.0032150670000000003,0.024052338,1.164682365,2.593359679,-2.866801642,-2.748287895,-3.6031698530000003,-3.127994614,-3.166368416,-1.688187431,-3.247831352,-2.293250483,-1464.3550592297688 -446,446,L47N,-0.10600271900000001,0.050773665999999995,-0.49401955,-1.9640183530000002,-2.469694379,0.082073102,-0.061264769000000004,-0.150740669,-0.056874042,0.03313762,0.068409711,-0.340682615,-0.647356484,-1.6224915469999999,-2.305545158,-2.253754905,-2.685633853,1.638452059,0.856767042,-6.8411724529999995,-7.262988686,-7.265125122000001,-8.115511696,-5.641012093,-5.92122467,-5.970605431,-3.9397398260000003,-1471.2770547163673 -447,447,L47Q,-0.038064366,0.008879526,-0.022764916,-0.044110424,-0.861640165,0.061419611,-0.071354488,-0.004774243,0.048251261,0.050343976,-0.032584924,0.008605251,-0.054135083,-0.033860878999999997,-0.054359968,-0.535073305,-1.188207025,0.896020182,1.48144071,-4.868536902,-5.512807648,-5.182126038,-5.85766468,-5.084257759,-2.7058283839999997,-3.488338919,-1.956936241,-1472.0730093801394 -448,448,L47P,-0.054203062,-1.385023975,-2.214168575,-2.314785103,-2.8388624539999996,0.08760109,-0.038753876,-0.069652247,-0.10422844099999999,-1.399029979,-1.371017971,-2.069727387,-2.358609762,-2.104133465,-2.525436741,-2.635026278,-3.04269863,-0.016062728000000002,-0.877195519,-9.009735564,-7.181129837,-9.440281127999999,-10.50915026,-10.43709023,-7.48102636,-6.369178056,-4.931618285,-1465.5823327749968 -449,449,L47S,-0.07002549799999999,-0.007096858,-0.018456814,-0.020467224,-1.746007831,0.069372182,-0.043688385999999996,-0.096362609,0.000648872,-0.000262822,-0.013930894,-0.003107562,-0.033806065,0.041012808,-0.081947256,-1.5593872340000001,-1.9326284280000001,0.637336306,1.315348132,-5.659641037,-5.75806395,-5.736384682000001,-6.606531242000001,-5.3315012589999995,-4.865724052,-4.761124145,-2.479968139,-1466.9289258862846 -450,450,L47R,-0.080554719,0.016674459,-0.18297436600000003,-1.659239406,-2.5072716369999997,0.061273978,-0.064869001,-0.096240436,-0.068280453,0.021681214,0.011667704,-0.036211181,-0.329737551,-1.3536954209999998,-1.9647833909999999,-2.103823368,-2.910719905,2.39919235,1.532607764,-3.940149925,-4.592226341,-4.209646461,-4.16333889,-4.3777554169999995,-2.357782516,-3.321682584,-0.513203665,-1464.2645572428592 -451,451,L47T,-0.040328411,-0.001473683,-0.035655427999999996,-0.02291643,-0.895189117,0.039661032,-0.040082386,-0.040574435,-0.007180999,0.00091807,-0.003865435,-0.019970855,-0.051340000999999996,-0.001897201,-0.043935657999999995,-0.597162906,-1.193215327,0.832025127,1.4515295019999999,-4.773603612,-5.008584503,-5.836343948,-5.590960892000001,-4.046418098,-3.385710617,-3.9306475780000003,-2.043393015,-1466.297933837399 -452,452,L47W,-0.054333674000000005,0.045842021,-0.033833415,-1.5498587240000001,-2.8026120480000003,0.115609702,-0.016967924,-0.091699424,-0.060595526,0.022970461,0.06871358,-0.00033124099999999997,-0.067335589,-1.187807583,-1.911909865,-2.8982521869999998,-2.706971909,0.526928949,0.7173101040000001,-5.462041212000001,-5.495563622000001,-5.76848262,-4.908272636,-7.233802811,-3.9040843730000003,-3.665933172,-2.603674053,-1459.4611794911325 -453,453,L47V,-0.039439073,0.017396459,-0.0026445809999999996,-0.018979753999999998,0.021797609,0.038118534,-0.061533559,-0.017344586000000002,0.04983869900000001,-0.012132021000000002,0.046924939000000006,-0.015472548000000001,0.010183387,-0.023450807999999997,-0.014508699,0.037644221,0.0059509969999999995,1.2219932820000001,2.781093991,-2.6022340330000002,-1.823110016,-3.7686521839999996,-2.462959427,-3.0539708560000003,-1.9024776840000002,-2.582547569,-0.576204739,-1460.971451469697 -454,454,L47Y,-0.063003098,0.01177264,-0.034851602,-0.020247827,-1.5723758980000002,0.054430947,-0.065430788,-0.060575408,-0.024064245,-0.061443837,0.08498911599999999,-0.057805878,-0.011897325,-0.005874305,-0.034621348999999996,-1.320531299,-1.8242204969999998,0.684650148,1.329924508,-3.9779014569999998,-3.512618256,-4.548266525,-4.123055901,-4.419074287,-3.286492317,-3.753863403,-1.9160399609999998,-1455.9965770663694 -455,455,D48A,-0.021167461000000002,-0.026105557999999997,-0.028627866000000002,-0.062238362,-1.202840841,0.020056556,-0.041043251,-0.00129167,0.0041560979999999996,-0.04063843,-0.011572686,-0.041359501,-0.015896231,-0.13548058300000002,0.01100386,-0.887827921,-1.517853761,1.2484802940000002,1.5070412569999998,-5.435668627999999,-6.135788757,-4.829159439,-3.4052073210000002,-6.794312851,-6.013874771,-4.986498452,-3.1735882330000003,-1460.8404068732634 -456,456,D48C,-0.065482569,0.004249118,0.012368206999999999,-0.138810352,-1.743934184,0.007393545,-0.095325718,-0.03563942,-0.062289300000000006,0.050359372,-0.041861136,0.0016393820000000002,0.023097031,-0.103963276,-0.173657428,-1.660553224,-1.8273151440000002,0.790422107,1.317627204,-8.630035666,-10.01272017,-9.23981955,-7.0369434360000005,-9.809575378,-7.051119797,-6.501858519,-4.630611443,-1466.0159075334668 -457,457,D48E,-0.030880974,-0.040698727000000004,-0.051885564,-0.084194609,-0.12991054,0.010224333,-0.053756930999999994,-0.008005017,0.009852059,-0.061937503,-0.01945995,-0.054017199,-0.049753927999999996,-0.118524125,-0.049865092,-0.118060601,-0.141760478,1.450597315,2.2655999159999998,-3.990808118,-4.337031647,-3.8632069319999998,-2.7406567,-5.405126632999999,-3.608018677,-3.9025589760000003,-2.9804423260000004,-1461.728678734973 -458,458,D48G,-0.11553479900000001,-0.079927229,-0.081447123,-0.082869369,-1.782656107,0.026251116,-0.122287467,-0.10878213099999999,0.002043347,-0.081035853,-0.078818604,-0.10049717,-0.062397075,-0.092794864,-0.072943874,-1.6733295209999999,-1.8919826919999998,1.080125408,1.3404552859999999,-6.822611116,-7.633766372999999,-4.67491539,-5.618289093,-9.188933449,-6.997151276,-5.414938788,-3.0633433389999998,-1459.1105406321585 -459,459,D48F,-0.120341789,-0.114151758,-0.270411348,-1.7294805309999999,-2.502426189,0.0109794,-0.15194222599999999,-0.088741351,-0.075662201,-0.030892282000000004,-0.197411234,-0.12023012300000001,-0.42059257200000005,-1.6964719080000001,-1.762489154,-2.419244827,-2.58560755,0.9058990020000001,0.700271235,-10.08087168,-11.81749217,-12.08206539,-8.334009338,-10.76854854,-7.402242966,-7.557286639,-5.774254865,-1461.978181542363 -460,460,D48I,-0.114177686,-0.051062237,0.010006417,-1.373383494,-2.340419237,-0.045748225,-0.162597926,-0.065757445,0.008418743000000001,-0.015652316,-0.086472157,-0.017302076,0.03731491,-1.132200478,-1.61456651,-2.118214831,-2.5626236430000002,2.2737298999999997,1.506362465,-8.876586653,-11.07857143,-10.74715301,-7.381396400000001,-9.74418438,-5.431628052000001,-6.271883715,-5.225569267,-1457.5681684026495 -461,461,D48H,-0.235753333,-0.08268299900000001,-0.144521035,-0.203239903,-1.852532013,-0.036863981000000004,-0.176050569,-0.295456096,0.05318096,-0.031602494,-0.133763504,-0.034567768,-0.254474301,-0.092900669,-0.31357913600000004,-1.4404767059999999,-2.264587319,1.177891237,1.3800280230000002,-5.380125072999999,-7.854518204,-7.348927413999999,-2.584703094,-5.460810562000001,-3.6516660919999997,-4.750180347,-2.360048297,-1457.794526415877 -462,462,D48K,-0.0024798579999999997,-0.045512168,-0.06520930000000001,-1.559207861,-2.633183513,-0.023727654,0.043077291,-0.048037007,0.086251945,-0.040656526,-0.05036781,-0.11311777199999999,-0.017300827,-1.5984053180000002,-1.5200104030000001,-2.446116973,-2.820250053,1.00722918,0.722007831,-8.182988864,-9.002752525,-10.04325862,-5.232564117,-9.26144902,-7.374920036000001,-6.582040207,-5.29313656,-1456.8730431497097 -463,463,D48M,-0.105161954,-0.121135801,-0.086154034,-0.250932596,-2.264804231,0.011928709,-0.133982868,-0.076341039,-0.006974205,-0.141581565,-0.100690036,-0.073845255,-0.09846281300000001,-0.250153093,-0.25171209899999997,-1.947371908,-2.582236554,1.338899069,1.340119628,-9.6177589,-11.79234985,-10.83293998,-8.024904022000001,-10.17396596,-7.264634697000001,-7.256929557,-5.459190575,-1464.022068618331 -464,464,D48L,-0.05298013,-0.088955561,-0.097753168,-0.8662987209999999,-2.3626222390000002,-0.03812019,-0.058270706,-0.047689554,-0.005580331,-0.06989354099999999,-0.108017581,-0.12215531,-0.073351026,-0.632281026,-1.1003164159999999,-2.098040779,-2.6272036990000003,1.701875386,1.352873286,-8.380416217,-11.16163553,-10.05157662,-6.947889351000001,-8.95133239,-4.789647194,-6.487669106,-4.0526626189999995,-1458.8483949047513 -465,465,D48N,-0.001229758,-0.087513551,-0.084490151,-0.043579313,-1.278640676,-0.08429493699999999,-0.009649878,0.007190363000000001,-0.013362177,-0.122330143,-0.052696959,-0.122691917,-0.046288384,-0.073270492,-0.013888133,-1.048176965,-1.5091043869999998,0.797038915,1.364972925,-4.140247929,-5.172585243,-5.396025497,-2.8448286510000003,-5.634287163,-1.6535130919999999,-2.7394183360000004,-1.394143348,-1461.6775428624824 -466,466,D48Q,-0.131961078,-0.07314618,-0.105064641,-0.111862622,-1.419343169,0.008091774,-0.20238143600000003,-0.06154072,0.02426692,-0.091545481,-0.054746879000000005,-0.147833796,-0.062295486,-0.16879114,-0.054934103,-1.295522101,-1.543164236,1.3046302220000001,1.429272254,-7.520102141000001,-8.746371414,-9.428718506000001,-4.403893005,-8.95201783,-6.0695099489999995,-5.718164588,-4.463772704,-1458.907220131252 -467,467,D48P,-0.080827336,-0.11438087,-1.269183872,-2.398424719,-3.204843771,-0.004874870999999999,-0.10773466,-0.053920011,0.006210483,-0.055903086,-0.172858653,-1.1632026659999999,-1.375165077,-2.241638598,-2.555210839,-2.788320258,-3.621367283,0.711781696,0.096134008,-9.039518199,-10.47138036,-9.546170471,-6.918922417,-9.631570824,-8.629546928,-6.871316575,-3.7344460660000003,-1462.7316351607442 -468,468,D48S,-0.074913959,-0.096409204,-0.054405515,-0.064171536,-0.813724545,0.024432878999999998,-0.09688527599999999,-0.052942642000000005,0.118417381,-0.04344034,-0.149378068,-0.061143509000000006,-0.047667521,-0.084699665,-0.043643405999999996,-0.613566991,-1.0138820990000001,1.416673241,1.7031394080000002,-5.163692212,-6.830438965,-4.054695892,-3.036894821,-6.587765289,-5.308666092,-4.447010527,-2.9711743160000004,-1458.810135407839 -469,469,D48R,-0.11589267,-0.0837135,-0.11721174599999999,-1.6651416469999998,-2.492796019,0.035414421,-0.134315481,-0.097469859,0.004127587,-0.057294667,-0.110132332,-0.077130002,-0.15729349,-1.546433271,-1.783850022,-2.322142265,-2.663449773,0.8295497190000001,0.7076000790000001,-6.257029062000001,-8.264170181,-7.541027778999999,-2.657672287,-6.89273999,-5.929535072,-5.331222598,-2.759665453,-1455.8135844534263 -470,470,D48T,-0.064041246,-0.108630535,-0.057822122000000004,-0.367886041,-2.654013198,0.010182702,-0.069768317,-0.058314175,0.057592699000000004,-0.09015537900000001,-0.12710569,-0.161425843,0.0457816,-0.315159943,-0.42061213799999997,-2.15048201,-3.157544386,1.702262833,1.358159087,-7.424551889,-9.218329796,-7.7203313289999995,-5.349161728,-8.602973022,-6.23196357,-5.79117872,-4.231739056,-1456.4549177624285 -471,471,D48W,-0.109849701,-0.040945854,-0.45716779399999996,-1.85071631,-2.496025715,0.028060288,-0.11683379599999999,-0.102865605,-0.06255472200000001,0.004283766,-0.086175474,-0.307053594,-0.607281993,-1.806129425,-1.895303195,-2.704993603,-2.287057826,1.397193541,0.7431151020000001,-9.987571747999999,-11.82792661,-10.29547212,-8.165910286,-10.90272674,-8.745822983,-7.624950393,-5.618271432,-1463.341732560657 -472,472,D48V,-0.123436205,-0.100342418,-0.076115092,-0.802442827,-2.229344399,-0.029461296,-0.119148332,-0.12772407800000002,0.117227071,-0.071392855,-0.12929198,-0.112590645,-0.039639537999999995,-0.508733714,-1.09615194,-2.227872348,-2.23081645,1.70056127,1.340006709,-7.671322885,-9.954720764,-9.650167519,-6.000151542999999,-8.642467163,-4.109107437,-6.420206583,-4.057035537,-1457.9624718381092 -473,473,D48Y,-0.12049191599999999,-0.112136982,-0.10733534900000001,-1.531847575,-2.515503785,0.09027948400000001,-0.124141695,-0.116842137,0.030967337,-0.095083228,-0.129190735,-0.12601986,-0.088650837,-1.659857797,-1.4038373530000001,-2.604479465,-2.426528104,1.026334181,0.714551904,-8.815443292000001,-11.13765137,-10.90940261,-6.745146523,-8.927507111,-6.3575088420000005,-6.6110460689999995,-4.396986032,-1458.0601478340104 -474,474,L49A,0.009349389,0.027332928,0.025682542000000003,0.055011924000000004,-0.398791157,0.13333304699999998,0.079372151,-0.060673372999999996,0.01561417,0.04270075,0.011965105,0.025337053,0.026028031,0.010342192,0.099681656,-0.314749226,-0.48283308799999997,1.070193421,1.722549574,-5.457597258,-3.935032722,-6.5913870160000005,-6.7633763810000005,-5.145233757,-4.852956413,-4.425792864,-2.822849572,-1463.6483590989374 -475,475,L49C,-0.021389187,0.017867822,-0.050937995,-0.07269455799999999,-1.730716884,0.143915038,0.086171289,-0.128949662,0.01049764,0.026932611000000002,0.008803033,-0.00948844,-0.09238755,-0.080019973,-0.065369143,-1.6481639940000001,-1.8132697740000001,0.8294104390000001,1.321010994,-7.1968489270000005,-6.918421295,-7.414606322999999,-8.045412674,-6.099771652,-7.506032692000001,-5.765158037999999,-4.073882429,-1460.3958872589283 -476,476,L49E,-0.050972354000000004,-0.01507065,-0.11613341,-1.629462955,-2.506298315,0.134466741,0.018211701,-0.120156409,-0.101759721,-0.04706364,0.016922341,-0.11310782900000001,-0.11915899099999999,-1.422198118,-1.836727791,-2.266929679,-2.74566695,1.0240189309999999,0.744975886,-8.526647083,-8.00509449,-8.315389046,-9.800883865,-7.740665572999999,-8.771202438,-6.99453887,-5.329296923999999,-1457.1137268948369 -477,477,L49D,0.041772056,-0.006964522,-0.8013396559999999,-1.836841629,-2.389768248,0.08594894199999999,0.121567522,-0.03802341,-0.011381275,-0.017441174,0.00351213,-0.63787737,-0.964801942,-1.298282455,-2.3754008030000002,-1.921165266,-2.85837123,3.992482255,2.95605532,-9.545601109,-8.309635139,-9.783354468999999,-10.31336359,-7.804341591,-11.51731075,-6.7227783389999995,-5.02631127,-1455.433329504449 -478,478,L49G,-0.064166624,0.008118386,-0.002153457,-0.320083165,-1.948571412,0.12403715800000001,-0.005082992,-0.123250256,-0.016565513,0.029607226,-0.013370453999999999,0.043468152999999995,-0.047775067000000004,-0.154749104,-0.485417225,-1.596316712,-2.3008261119999998,1.142290726,1.356521415,-7.374615791,-5.908962562999999,-8.398892944,-8.771806847,-6.253803734,-7.539612869,-5.466906267000001,-4.2122122289999995,-1458.337871632073 -479,479,L49F,0.02032381,0.032874772000000003,-0.033435021,-0.009401590999999999,-0.12134167,0.039480809,0.101180947,-0.060533327000000005,-0.012496168,0.047206276,0.018543267,-0.00948844,-0.057381601,0.0068000840000000005,-0.025603265,-0.130049039,-0.1126343,1.30067394,2.192009275,-4.206474565,-3.8890072019999997,-3.5334593510000003,-5.698352531,-3.880069344,-4.031484398,-5.320025335,-2.76166752,-1455.984731993638 -480,480,L49I,0.036011655,0.070637907,0.029063234,0.087087169,0.025955322000000003,0.057718676,0.09683095,-0.024807641000000002,0.053431942,0.09419010800000001,0.047085705,0.086334478,-0.02820801,0.128152554,0.046021783,0.034742236,0.017168408,1.123099029,2.88447331,-4.201768993,-4.49939605,-3.979560875,-5.099177238,-3.776219185,-3.654491615,-4.987080959,-1.633741849,-1464.7079004673287 -481,481,L49H,0.037321676,0.040130584,0.016879658999999998,-0.30972323399999996,-1.904127979,0.080282989,0.110478231,-0.035834879,-0.083165663,0.043975350999999996,0.036285817000000005,0.004107976,0.029651342,-0.235894832,-0.38355163600000003,-1.51731899,-2.290936968,1.391661667,1.418493416,-8.119471825,-7.036610275,-7.789581207,-9.343039856,-6.60913475,-9.818993034,-6.379508257,-4.8968305910000005,-1458.3480411469936 -482,482,L49K,-0.023105191,-0.015099101,-0.055811554000000006,-1.172874741,-1.8574220769999998,0.092617117,0.043165542,-0.08937592300000001,-0.035995509,-0.027003846,-0.003194355,0.0075449,-0.11916800699999999,-0.7156510159999999,-1.630098465,-2.078896516,-1.635947637,1.701504418,1.3525151930000001,-6.80907211,-6.085711197,-7.006059845,-8.131258675,-6.679611641,-6.142719193,-5.487785693999999,-4.780601221,-1462.98675298132 -483,483,L49M,-0.025127699,0.009347731,-0.032989389,-0.0039046209999999996,0.008772386,0.065390268,0.004610341,-0.054865738,-0.036097686000000004,0.052901212,-0.03420575,0.031129411000000003,-0.097108189,0.045372268,-0.053181509,0.010800848,0.006743923000000001,1.144223292,2.691488135,-3.906448198,-3.4795968630000003,-4.386310905,-3.644842995,-4.088151375,-3.933338852,-5.054741694,-3.040362369,-1464.0625122254714 -484,484,L49N,-0.007183726999999999,0.017364313,-0.054132898,-0.37150374399999997,-1.9282989640000001,0.10714061300000001,0.053262029,-0.067629483,-0.103100289,0.010271114,0.024457512,-0.079657665,-0.02860813,-0.20027932699999998,-0.54272816,-1.770774069,-2.085823858,1.2418821000000002,1.349998314,-8.368614497000001,-7.795747177000001,-7.38650573,-9.930825783,-7.014296379,-9.715697418,-6.592324491,-4.151768701,-1460.0691269715317 -485,485,L49Q,-0.122437675,-0.024370565,-0.067796907,-0.09092469800000001,-1.7597983990000001,0.172771444,-0.065991565,-0.178883785,-0.045454654000000004,0.026513727999999997,-0.07525485700000001,-0.035295703,-0.10029811,0.025722837000000002,-0.207572233,-1.929598434,-1.589998363,0.590648405,1.296740411,-6.637604391,-5.722825622999999,-6.389389397,-7.7175752939999995,-5.719410827999999,-7.638820816,-5.175834603999999,-4.4689533610000005,-1462.4248026036657 -486,486,L49P,-0.028853608,0.024618252,-0.004727614000000001,-0.244371135,-1.963572886,0.108744719,0.057783565,-0.11549078,-0.089990344,0.023801475,0.025435028999999998,0.011027928999999999,-0.020483156000000002,-0.121030383,-0.367711886,-1.80662293,-2.1205228419999997,0.9783723940000001,1.320525046,-4.882713327,-4.383366791,-5.3001195139999995,-5.742442116,-4.44438121,-4.543257004,-4.016912262,-2.350246851,-1460.4294234616682 -487,487,L49S,-0.027019788,-0.012416005,-0.022086376,0.002435373,-1.6766709219999998,0.11216828,0.057931305,-0.111970881,-0.00752886,0.010928307,-0.035760317,0.008531186,-0.052703937,0.018574518,-0.013703772,-1.344999869,-2.008341975,0.78865909,1.338309624,-5.546601926,-4.828681823999999,-5.266731285,-6.797354912,-4.885446953,-5.954794655,-4.195069406,-2.669018597,-1461.734466032125 -488,488,L49R,-0.0076694680000000005,0.006198338,-0.036104698,-1.39980136,-2.058053405,0.092936331,0.038281703,-0.053620638,-0.080341118,-0.011225215,0.02362189,0.0017070339999999999,-0.073916429,-1.083368443,-1.7162342769999999,-1.490933372,-2.625173437,3.555143042,2.8807042089999997,-7.1962183589999995,-4.844845825,-7.79799662,-8.165689331,-6.389884467999999,-8.782675552,-5.561558235,-4.512566393,-1462.3124886844307 -489,489,L49T,0.027307709,0.020935829,-0.007092364,0.003132137,-0.566029879,0.075163415,0.088277447,-0.033662028999999996,-0.020952672,-0.030656021000000002,0.072527679,0.000611887,-0.014796615,0.0070444819999999995,-0.000780208,-0.46115632100000004,-0.670903437,0.756821849,1.468778458,-4.128080345,-3.117119972,-4.889680756000001,-4.994410072,-3.749801727,-3.889389198,-3.119054137,-0.258416625,-1465.201974734664 -490,490,L49W,0.051489205,-0.007868046,0.018648243999999998,0.01802376,-0.076008527,0.054655533,0.09516925400000001,0.007809155999999999,0.005888109,0.021086182000000002,-0.036822272999999996,0.030752778999999997,0.006543709,0.024839426,0.011208093,-0.016414935,-0.135602119,1.4848678430000002,2.833193077,-9.161803276,-8.75562529,-8.953390945,-9.456890747000001,-8.146909698,-10.496199699999998,-8.343969717,-7.057598991,-1458.8242718619294 -491,491,L49V,0.019838762,0.038435602,0.034548711,-0.006204268000000001,-0.043917615,0.073670734,0.098679154,-0.05900163,-0.034816585,0.054191768,0.022679436,0.111489675,-0.042392253,0.06792521900000001,-0.080333755,-0.005456366999999999,-0.082378863,1.227003906,2.729191112,-3.729945303,-3.74064769,-3.9293603439999996,-4.5862417980000005,-3.98576049,-2.4077161940000003,-3.506266077,-1.7379779180000001,-1465.2525591971353 -492,492,L49Y,0.004036225,0.016423706,0.0053643480000000006,-0.004842150999999999,-0.105296504,0.104310184,0.05043952,-0.042367071,0.005522336,0.023349396,0.009498015,0.016593362,-0.005864666,0.025067903,-0.034752204,-0.08315244299999999,-0.127440564,1.307360183,2.3420552519999998,-6.931931645,-6.5976871489999995,-6.528364868,-8.117919441,-5.417604927,-7.998081841,-6.2466944820000005,-3.9382902160000004,-1453.3046681378037 -493,493,N50A,-0.008084997,-0.010696856000000001,-0.036183766,-0.002009195,-0.032218326,-0.001880045,-0.012713661000000001,-0.0034563320000000003,0.045044948,-0.026481223999999998,0.005087513,-0.009799657,-0.06256787400000001,-0.003001677,-0.001016713,-0.030726706,-0.033709946,1.297699302,2.592330939,2.2259235719999997,1.8297348180000002,2.450700096,3.0323687130000003,2.3535903240000002,1.463223907,0.400537436,1.050228126,-1461.036663540639 -494,494,N50C,-0.019290946,-0.029554896,-0.013085316999999999,0.027809537000000002,-1.223080702,0.094070154,0.015158235,-0.053740127,0.004290877,-0.017488304,-0.041621488,0.020282463,-0.046453097,-0.003367603,0.058986677,-0.851844498,-1.594316905,0.406638,1.336012309,-3.64956243,-3.7607690810000003,-3.199836121,-2.476058411,-3.9504446110000004,-4.860703926,-5.2432662919999995,-4.2966612060000005,-1460.2257196973078 -495,495,N50E,-0.010813871000000001,-0.023545543,-0.060759267,-0.006930653,-0.017852372,-0.032640196,-0.033614369,0.011986628000000001,0.066806717,-0.029349772000000003,-0.017741313999999998,-0.039526473,-0.08199206,-0.034967358,0.021106053,-0.020463977,-0.015240766000000001,1.274597881,2.5472242119999997,-0.01725918,0.191334946,0.371022591,0.774214348,-0.838738647,-0.584129135,-1.6390932280000001,0.7687530359999999,-1457.7857446465641 -496,496,N50D,-0.000362991,-0.001021611,-0.000616795,0.031498602,-0.01891356,-0.056921607,-0.028705487999999998,0.027979506,-0.01299482,0.014256395,-0.016299617,0.013993381000000001,-0.01522697,-0.006421268000000001,0.069418471,-0.012425397,-0.025401722999999998,1.296986275,2.686218378,-0.21624642600000002,-0.489789825,-0.296828812,-0.176204269,-0.037966698,-0.080442528,-2.757522432,1.189025998,-1461.0048334891908 -497,497,N50G,0.010918123,-0.011505466,-0.012991626000000001,0.013356463999999998,-0.018879235,-0.019337947,0.002186642,0.019649603,0.027401514,-0.026275782,0.00326485,-0.013422628,-0.012560624,-0.018677283,0.04539021099999999,-0.042923502999999995,0.005165033,1.4636455019999999,2.58767748,0.254996309,0.581983315,0.148864204,0.684148949,0.8590724259999999,-0.9990873490000001,-0.856568856,1.4604560130000002,-1458.5317568914033 -498,498,N50F,-0.000322013,-0.039831523,-0.0046451470000000005,-0.014366638999999999,-0.082938465,0.0028897959999999996,-0.004918116,0.00427409,0.047196745,-0.041833332,-0.037829714,-0.006184821,-0.003105473,-0.017278688,-0.01145459,-0.091616967,-0.074259963,1.230673727,2.2066767780000003,-3.587364079,-3.609142075,-3.1745982280000002,-2.542659355,-4.07961438,-4.530806358,-5.335282447,-3.625255995,-1461.1971651348285 -499,499,N50I,-0.007572026999999999,-0.053279155,0.00296178,0.040509752999999996,-0.050837260999999995,-0.015527808999999998,-0.036051868,0.020907815,-0.015567777,-0.071961083,-0.034597226,-0.0038257729999999998,0.009749333,-0.01649428,0.09751378599999999,-0.05649143400000001,-0.045183087999999996,1.315948249,2.403880648,-1.970203613,-1.706909698,-1.450253075,-0.9756854779999999,-2.3660438999999998,-3.3521259160000003,-4.658404872,-2.2496345509999998,-1462.3493250580505 -500,500,N50H,0.02568454,-0.007074709,-0.002432786,0.057300434000000004,0.010744473999999999,-0.027480612,0.004180202,0.047188878,-0.060775539,-0.020669504,0.006520087,0.000924055,-0.0057896269999999994,0.031719916,0.082880951,0.001127745,0.020361203,1.170341736,2.572464589,-0.970511105,-0.013208983999999998,-1.108956573,-0.457947472,-1.7241500930000002,-1.5482924040000001,-2.619911038,-1.105208958,-1461.2001709151082 -501,501,N50K,0.038498322,0.030005389,0.036899416000000004,0.020504778,-0.000322556,-0.011371362,0.043571270999999995,0.033425372,-0.035305857999999996,0.0023998229999999997,0.057610955,0.056866925,0.016931906,-0.00741841,0.048427965999999996,0.00143379,-0.002078901,1.177895262,2.6053618,0.165758078,0.71181105,0.634507935,0.6136717070000001,-0.838377167,-0.292823135,-2.7293754889999997,0.153071996,-1460.5558369159698 -502,502,N50M,0.025102831000000003,0.08440997,0.070633363,0.061432125,0.051670550999999995,-0.033725571,0.026342955,0.023862707,-0.014325853999999999,0.087391532,0.08142840700000001,0.073637135,0.06762959,0.077752052,0.045112198,0.048596027,0.054745074000000005,1.1122792190000002,2.6324447930000003,-2.7263591419999997,-2.9214538039999995,-1.9133663330000001,-1.986578133,-3.002580048,-3.80781739,-4.956621297,-3.4971831489999996,-1461.3000847483054 -503,503,N50L,0.004176773,-0.003928236,0.0027932440000000003,0.035434022999999995,-0.025187337999999997,0.011849506999999999,-0.000929413,0.009282959,0.018310207,-0.005951341999999999,-0.001905129,-0.000528841,0.006115328000000001,-0.013932711,0.08480075599999999,-0.026614968,-0.023759707,1.4150288999999998,2.619920111,-1.746993504,-1.7708842009999999,-1.0075930020000001,-0.7902606120000001,-1.885758064,-3.2804716419999997,-3.560377453,-2.7220580869999997,-1460.7847563992254 -504,504,N50Q,-0.034149908,-0.025746897,-0.0055602740000000005,-0.0048038379999999995,-0.030864238999999998,-0.026081816,-0.070732568,0.0024327520000000003,-0.080925792,-0.040319285,-0.011174509,0.001889087,-0.013009635,-0.047476969,0.037869293,-0.002095514,-0.059632964000000004,1.2387622759999999,2.562574386,0.18016377600000003,0.761212715,0.252830681,0.6724545670000001,-0.659473778,-0.126205307,-2.391201077,-0.19100037399999997,-1462.1575180240907 -505,505,N50P,-0.023845295,-0.023818331,-0.04224872,-0.004277632,-0.037237915,0.019940608999999998,-0.027595201,-0.020095388999999998,-0.05125764,-0.028868498,-0.018768164,-0.033057906,-0.051439534,-0.039822982,0.031267718,-0.031779322,-0.042696507,1.34675048,2.55281712,-1.500244243,-1.6503931580000002,-1.89874144,-1.011499504,-0.812555473,-2.128031639,-4.168961106,-1.4798279490000001,-1451.2648476646282 -506,506,N50S,0.005311758000000001,0.008731341,0.002270534,0.035178948,-0.013873543,-0.0035212240000000003,0.005232586,0.00539093,0.018288786,-0.006976869,0.02443955,0.030300538,-0.025759471000000003,0.022035366,0.048322529,-0.004379002,-0.023368084,1.211511191,2.5712777780000002,0.558419965,0.226065842,0.882407875,1.171736046,0.49760156299999997,0.014288498,-1.8701244259999998,-0.053767358,-1459.8066434767097 -507,507,N50R,-0.023695211,-0.023526738999999998,-0.020184106,0.018598537,-0.036412892999999995,-0.017556824,-0.031681548999999996,-0.015708873,-0.02769758,-0.021082536000000002,-0.025970941,0.005270632,-0.045638844000000005,0.0061453390000000005,0.031051733999999998,-0.011810751000000001,-0.061015035,1.3081624109999999,2.665652859,-0.215722052,0.604579834,0.275983498,0.7266398159999999,-1.117773582,-1.568039825,-2.464228779,-0.042224125,-1458.5256342035718 -508,508,N50T,-0.014458038999999999,0.015155161,0.0032819570000000003,0.006063689000000001,-0.008385861,-0.004020308,-0.034910673999999996,0.005994597,-0.012008907,0.006723221,0.023587101,0.017023227,-0.010459313000000001,-0.010463799000000001,0.022591176,-0.005723173000000001,-0.011048549,1.215730156,2.850969187,0.7814481809999999,0.423739418,1.498049065,1.4379926219999999,0.85495237,-0.307492569,-1.138271929,-0.19074585300000002,-1457.0643478929996 -509,509,N50W,-0.0015829079999999998,0.008164795,0.013075457,0.011461233999999999,-0.021802642999999997,0.014398281,-0.008749722,0.005583906,-0.042639055999999995,-0.006706111,0.0230357,-0.008355088,0.034506001,0.015032656,0.007889812,-0.046507617,0.0029023309999999997,1.1321617,2.338242551,-4.470520325,-3.93557135,-4.3416647489999995,-3.633132561,-4.841911774,-5.60032119,-5.976090782999999,-4.091725199,-1459.056041748263 -510,510,N50V,0.004001322,-0.020066022,-0.030175905,0.0158949,-0.016311532,-0.024784184,-0.013346486999999999,0.02134913,-0.001813341,-0.041030499,0.0008984560000000001,-0.030887137000000002,-0.029464672999999997,-0.015422700000000001,0.0472125,-0.035472317999999996,0.0028492540000000003,1.194165551,2.437284771,-0.18853255300000002,0.055017342000000004,0.674477478,0.9079105909999999,-1.039512703,-1.5405554730000002,-2.4907028280000003,-1.178196581,-1461.6458682008088 -511,511,N50Y,0.008904689,-0.01490496,-0.007164311,0.0052608690000000005,-0.041849916,-0.009206242,-0.00633791,0.024147288,-0.04517863900000001,-0.028905446,-0.000904474,-0.060033695,0.045705073,-0.024686081000000002,0.035207819,-0.062449657,-0.021250174,1.258514628,2.348652214,-3.372337065,-2.6386307909999998,-3.194357246,-2.819585014,-3.834533493,-4.374578781,-5.096726983,-3.1133120080000003,-1458.8899407121353 -512,512,S51A,-0.003110825,0.0039510990000000005,-0.002442861,0.00882037,-0.739318788,0.024115962999999997,0.002104804,-0.008326454,-0.013147998999999999,0.0036820940000000003,0.0042201040000000006,-0.021728466000000002,0.016842745,-0.013778041999999999,0.031418781,-0.505529847,-0.9731077290000001,1.151533062,1.621697353,-3.0278721369999997,-2.941236496,-2.868091484,-3.423185524,-2.181104836,-3.7257423480000003,-5.461872252,-2.343243786,-1464.1364303473383 -513,513,S51C,-0.044688877,0.04816891,-0.032840674,-0.7806645590000001,-1.8187439930000002,0.104584094,-0.015782624,-0.07359513,-0.102106469,0.096158638,0.000179181,-0.058497062,-0.007184286,-0.468763857,-1.0925652609999998,-1.6840355359999999,-1.95345245,1.7562629330000001,1.4843052959999998,-7.2528247420000005,-7.147603569,-7.074056937999999,-7.5452739179999995,-7.076808739,-7.420380547000001,-8.046940046,-4.016271463,-1467.528058600612 -514,514,S51E,-0.024542575,0.008071454,0.012977032,-0.004208255,-0.086824363,0.03604074,-0.045042871,-0.004042279,0.008550784,-0.025929063999999998,0.042071972,0.010381706,0.015572358,0.020291975,-0.028708485,-0.07252976900000001,-0.101118956,1.311983428,2.384162345,-3.871490565,-3.833378555,-3.3650324780000003,-4.282151802,-2.713734848,-5.163155144,-5.9192918510000005,-2.2283248419999997,-1458.9734201682732 -515,515,S51D,0.010510866,0.05345856400000001,0.052309327,0.086368427,0.075247281,0.044138814000000005,0.0031317940000000002,0.017889938,-0.096845128,0.020697981,0.086219147,0.044549621,0.060069032,0.10654020300000001,0.066196651,0.074847804,0.075646758,1.12715838,2.9269820889999996,-2.454435864,-2.94208355,-2.0708425669999997,-2.443288925,-1.519681465,-3.2962828139999996,-4.078479491,-0.965591405,-1459.6524354661815 -516,516,S51G,-0.011771686000000002,-0.025383054,-0.042533506,-0.004001896,-0.36904324899999996,0.019691329,0.017543543,-0.041086914,-0.09799392400000001,-0.06165488400000001,0.010888776999999999,-0.067776709,-0.017290303,-0.061332715,0.053328923,-0.297714451,-0.440372046,1.287357844,1.840626853,-2.611165483,-2.611798157,-2.0271894,-3.066989006,-1.471996712,-3.8778541410000003,-4.407296703,-0.915042685,-1457.9710988244042 -517,517,S51F,-0.035170724,0.10573728199999999,0.033076164,-0.042512380999999995,-1.75070567,0.080784026,0.017316009,-0.087657457,-0.109479009,0.117052398,0.094422165,0.094471129,-0.028318801,-0.114003916,0.028979155,-1.7320144869999998,-1.7693968519999999,0.839714032,1.315902222,-7.835615195,-7.277496925,-8.014218796,-7.443705856,-8.838178597,-7.6044758,-7.534595329,-3.9354022160000004,-1463.156354650855 -518,518,S51I,-0.037858996,0.010978864,-0.08603620099999999,-0.12256795,-1.3358577059999999,0.03767522,0.0008225060000000001,-0.076540498,-0.083073513,0.006331635,0.015626092,-0.055225953,-0.116846449,-0.021163636,-0.223972263,-1.3119146879999999,-1.3598007230000002,0.806239679,1.3435049330000002,-8.267238387999999,-7.683211151,-9.09937365,-8.837461647000001,-8.609893585,-7.106251907000001,-8.590728581,-5.655949529,-1464.7065870794468 -519,519,S51H,-0.054228684000000006,0.0054848430000000005,-0.064991767,-0.032996085,-0.605656207,-0.033705065,-0.049184278,-0.059273089,-0.09714614099999999,0.038050709,-0.027081023,-0.030288051,-0.099695483,-0.058124565999999996,-0.007867604,-0.42029362600000003,-0.7910187870000001,1.428583659,1.8655639659999999,-6.307050037000001,-6.362521996,-6.069293854,-5.781919014,-5.9927863310000005,-7.328728989,-7.237775376,-4.132124773,-1457.6236050170846 -520,520,S51K,-0.006533424,0.005048771,-0.093152136,-0.080652788,-0.6689583339999999,0.07220687,0.048637355,-0.061704203,-0.119065481,-0.016599262,0.026696803999999998,-0.13731219,-0.04899208099999999,-0.09405368900000001,-0.067251886,-0.44670727600000004,-0.891209391,1.449739916,1.841853729,-4.354200017,-4.316860825,-4.09650045,-4.531218788,-3.8721615369999998,-4.9542584839999995,-6.352390757,-2.704196405,-1455.3631641743705 -521,521,S51M,-0.00846214,0.03231386,0.02757966,-0.011123828999999998,-1.386030888,-0.007682441,-0.025330468,0.008406188,-0.081490858,0.011582936,0.053044783,0.0015388720000000002,0.053620447,0.002445255,-0.024692912,-1.148562968,-1.6234988080000001,0.705857139,1.344347789,-7.432698781,-6.830210938,-7.346100975,-8.393603012,-7.840288414,-6.753290565,-7.830402536,-5.191827577,-1465.8251180383377 -522,522,S51L,-0.0022791929999999997,0.021024867000000003,-0.003305348,-0.008331066,-1.4616226030000001,0.067083038,0.030187877999999998,-0.034746264,-0.11909463,0.000102935,0.041946798,-0.027660432000000002,0.021049737000000002,-0.036061742,0.01939961,-1.373298063,-1.549947142,0.818098972,1.338460985,-7.41173073,-6.863543877000001,-7.307715195,-8.22782988,-8.244294449,-6.415270248,-7.437962989,-4.726175625,-1462.9410057612695 -523,523,S51N,0.012952954,0.044632218,0.025758462000000003,0.037980149,0.017691821,-0.009411787,0.000466381,0.025439527000000003,-0.081189369,0.009704242,0.079560193,-0.018141268000000002,0.06965819200000001,0.00282491,0.073135387,0.0040961240000000005,0.031287517,1.1435320759999998,2.702124819,-2.258556158,-2.811522507,-2.279665062,-2.3816689380000002,-1.338768349,-2.481155937,-3.898803444,-1.192555578,-1459.6261944109574 -524,524,S51Q,-0.014713446000000002,-0.034990407,-0.019036116000000002,-0.023834078999999998,-0.454083284,0.009577845,0.006072406999999999,-0.035499298,-0.09589581900000001,-0.065663737,-0.004317077,-0.012125125,-0.025947107,-0.018350611,-0.029317546,-0.271114101,-0.6370524670000001,1.385069754,2.021961315,-5.034011494,-5.058857224,-4.77027462,-4.957090347,-4.216345703,-6.167489578,-6.145465445,-3.237922399,-1460.8294425564818 -525,525,S51P,-0.062556613,-0.007302388000000001,-0.276801636,-1.687142933,-2.620159281,0.086343981,-0.03463264,-0.090480586,-0.102501425,-0.006680586999999999,-0.007924189,-0.226428925,-0.327174346,-1.6181337169999999,-1.7561521480000002,-2.56153363,-2.6787849319999997,1.292604661,0.756880075,-6.937806532000001,-5.962718079,-6.621341567999999,-6.86277375,-7.021867477000001,-8.220331787000001,-7.251630502,-3.5850306830000003,-1454.4418341317214 -526,526,S51R,-0.02499057,0.0028453190000000002,-0.014492931,-0.01861232,-1.166772263,0.055392326,0.016255882,-0.066237022,-0.048319258,0.027761782000000002,-0.022071145,-0.020645703,-0.008340158,-0.040765707000000005,0.003541067,-0.83249896,-1.501045565,0.9259420279999999,1.4212439319999999,-3.9978607860000004,-3.7832409210000004,-4.080841171,-3.5212994610000004,-3.37298732,-5.230935059,-5.785746712000001,-2.413292354,-1457.3447178322822 -527,527,S51T,-0.029466071,-0.02768787,-0.010498036,0.002427636,0.006249996999999999,0.0068755069999999995,-0.02033942,-0.038592721,-0.020247936,-0.021796997000000002,-0.033578743,-0.002413765,-0.018582306,-0.013253448999999999,0.01810872,0.005396449,0.007103544,1.312553584,2.661026548,-0.9036472090000001,-0.8193224640000001,-0.824447632,-1.401025665,-1.502978355,0.029538071000000003,-3.137374733,0.47825707700000003,-1461.6506687090732 -528,528,S51W,0.001588234,0.003864143,-0.000930465,-1.257708532,-2.260674765,0.099042763,0.025701697000000003,-0.022525229,-0.097666566,-0.026890097999999998,0.034618382999999996,-0.019694977,0.017834048,-1.069810325,-1.445606739,-1.749968803,-2.7713807260000003,2.825242121,2.091728656,-8.809051311000001,-8.198051941000001,-8.730688751,-9.177346962,-8.570997597,-9.368171302999999,-8.73605875,-6.163029839,-1465.9465463892557 -529,529,S51V,0.044296827999999996,0.035245693,0.023986122000000002,0.024310053999999998,-1.719458446,0.070797273,0.093772269,-0.005178614000000001,-0.11410686699999999,0.014602406,0.05588898,-0.018460083999999998,0.066432328,-0.010619651,0.059239759,-1.451761355,-1.987155536,0.713452036,1.3220253290000001,-7.48566114,-7.014602699,-7.7567631,-8.047302361,-7.371370811,-7.238266731,-7.909634371,-4.879930185,-1461.9636928760447 -530,530,S51Y,-0.0021061,-0.001298404,0.006027365,0.014509847,-1.4192678380000001,0.021413274,0.005692476,-0.009904675,-0.169446028,-0.005156428,0.00255962,0.009832789,0.002221941,0.012159049,0.016860643999999998,-1.322282954,-1.5162527209999999,0.811011548,1.340853164,-8.981587416,-8.56538324,-9.443399207999999,-8.187927803,-9.384058197,-9.327168633,-8.31440531,-5.624510435,-1459.5740347886458 -531,531,G52A,-0.047540555,-0.026315206,-0.001094208,0.004574982,-1.397547239,-0.020527633,-0.0776331,-0.017448009,0.042918952999999996,0.024074044,-0.076704455,0.036529686,-0.038718102000000004,0.03971082,-0.030560856,-0.941951731,-1.853142747,0.7054294320000001,1.362729995,-4.268182642,-4.54104258,-2.812916542,-3.755971764,-4.200309708,-6.030672615,-3.850479131,-3.44375813,-1463.501856093295 -532,532,G52C,-0.050390135999999995,0.011548613000000001,-0.506589603,-1.3907311180000002,-2.765819379,0.100262251,-0.05765877,-0.043121501,-0.039428825,0.055839367,-0.032742142,-0.274332415,-0.738846791,-1.3442512919999998,-1.437210944,-2.422823856,-3.1088149019999998,1.551748794,0.893002159,-8.177728903,-7.754408089,-7.589241081,-7.454473335,-8.278901199,-9.811620811000001,-7.6510984120000005,-7.248742476,-1466.6838167123497 -533,533,G52E,-0.052895474000000005,-0.011349755,-0.02519872,-0.017728775,-1.4854190390000002,-0.032505387999999996,-0.05358206,-0.052208887999999995,-0.09541881599999999,0.038979189,-0.061678698,0.025661311000000003,-0.07605875,-0.02301791,-0.012439638999999999,-1.274221201,-1.6966168769999999,0.637829016,1.329612933,-3.8579845489999998,-4.01368042,-2.714966103,-4.00724408,-4.125222305,-4.428809837,-4.399830894,-3.096078355,-1464.3846895317547 -534,534,G52D,-0.025476422000000002,-0.028010881,0.037914649,-0.02815374,-1.142466432,0.002442821,-0.04527852,-0.0056743240000000006,0.042917138,-0.013377638,-0.042644123,0.049065029,0.026764269,-0.010629476,-0.045678002999999995,-0.962918321,-1.3220145429999999,0.523897175,1.339254332,-3.233483171,-3.293809402,-1.927869896,-2.8143798139999996,-3.9269789580000003,-4.204377785,-2.827768827,-2.447173425,-1465.5115868444555 -535,535,G52F,-0.07096396,-0.013820836000000001,-0.018118286,-0.247686319,-2.243396686,-0.016991139,-0.070077948,-0.071849971,-0.022227933999999998,-0.017791971,-0.009849700000000001,-0.004414365999999999,-0.031822205,-0.202114679,-0.293257958,-1.588556664,-2.8982367069999997,1.261669133,1.3766186980000001,-8.377659857000001,-7.5536494979999995,-7.743204414,-7.701173645,-7.895915733,-10.994356,-7.578358091,-6.636905811,-1463.1359274340793 -536,536,G52I,-0.065158743,-0.087096005,-0.355802644,-1.850621565,-3.029309641,0.048424759000000005,-0.080932764,-0.049384721,0.02651815,-0.044143497000000004,-0.130048513,-0.304647627,-0.406957661,-1.693744671,-2.007498458,-2.580431709,-3.478187573,1.405429449,0.767937278,-8.342276598,-7.669541946,-7.594753548,-7.287010917999999,-8.523553291,-10.63652328,-7.820823138,-6.99200141,-1460.5055610034615 -537,537,G52H,-0.075044202,-0.07975103900000001,-0.03525133,-0.035948583,-1.650707599,-0.035912141,-0.09157193699999999,-0.058516465999999996,0.064000705,-0.0013215710000000001,-0.158180507,-8.070000000000001e-05,-0.07042196,-0.0037871009999999997,-0.068110064,-1.4360168690000001,-1.8653983280000002,0.7058332540000001,1.325144169,-5.376852747,-4.926141823,-5.2453886569999995,-5.3051316680000005,-5.53918927,-5.868412315,-5.245564759,-4.166941142,-1463.7922978857532 -538,538,G52K,0.003140753,-0.059740260999999996,-0.010615719,-0.12128259599999999,-1.6790063030000002,-0.002956593,-0.014326261000000002,0.020607767,0.065659698,-0.050033377000000004,-0.069447145,-0.032402119,0.011170682,-0.104205139,-0.13836005199999998,-1.8148009180000002,-1.5432116880000002,1.030317726,1.323075299,-4.312924689,-3.993909683,-4.020330437,-4.442755562,-4.4728763119999995,-4.63475145,-4.3419704789999995,-2.686857259,-1462.9124707058072 -539,539,G52M,-0.058545358,-0.022569127,-0.019596767,-0.08402447,-1.645114846,-0.0298781,-0.082441869,-0.034648847,0.016701069,0.007510878,-0.052649132,0.002371624,-0.041565158,-0.08027142599999999,-0.087777513,-1.601920625,-1.688309066,0.8577023220000001,1.326226282,-8.261242461,-7.393528656,-7.481476265,-7.034510704,-8.138826836,-11.25786984,-7.198189641,-6.636905608999999,-1465.9530514515936 -540,540,G52L,-0.012440136999999999,-0.019598826,0.007416516,-0.23253181,-1.7372405359999998,-0.012168779,-0.023668024,-0.00121225,-0.008176188000000001,-0.014041591,-0.02515606,-0.006998167,0.021831198,-0.156140096,-0.30892352300000003,-1.72786136,-1.746619712,1.083384718,1.335722885,-6.835377272000001,-5.998673912,-6.164090988,-5.914792792999999,-7.151677841000001,-8.947650826,-6.12304038,-5.109115458,-1462.0707528330386 -541,541,G52N,-0.016179965,-0.015956314,-0.001694975,-0.040297307000000004,-0.5645407379999999,-0.066773254,-0.050902375,0.018542446,0.158885754,0.051521137,-0.08343376400000001,0.028827852999999997,-0.032217802000000004,-0.036406108,-0.044188505999999995,-0.49615074200000003,-0.632930734,0.7623519870000001,1.462077457,-2.9940635560000004,-3.450037231,-2.818676483,-3.051779533,-3.559275009,-2.090549522,-3.2632017060000003,-2.151628657,-1466.037592664361 -542,542,G52Q,-0.043054485,0.027510531,-0.004828025,0.016663182,-1.581973632,-0.038198188,-0.047786604,-0.038322366000000004,0.048540575999999995,0.051342847999999996,0.0036782140000000004,0.010680771,-0.02033682,0.049031902999999995,-0.015705538999999998,-1.397277835,-1.766669429,0.616904972,1.320265214,-4.290208435,-3.903479218,-3.9610475689999998,-4.058373238,-4.404859032,-5.123283119,-4.257980327,-3.2721994010000004,-1465.5073383133858 -543,543,G52P,-0.031945269,-0.018313373,0.01099754,-1.06203159,-1.923346365,-0.000876739,-0.057458813,-0.006431724000000001,-0.000892616,-0.001431701,-0.035195045,0.030398473999999998,-0.008403394,-0.703383709,-1.420679471,-1.9090610719999999,-1.9376316580000001,1.928080616,1.469151095,-5.095099393,-5.17498925,-3.360198647,-5.118368515,-5.863037376,-5.958903175,-4.855248352,-3.515278934,-1459.5054533691145 -544,544,G52S,-0.010350649,-0.019063312,-0.009109004,0.020904795,-1.555244441,-0.049930759000000005,-0.035894959,0.015193661,-0.025542684,0.004021938,-0.042148560999999994,0.005262780999999999,-0.023480788,0.0366098,0.00519979,-1.484761705,-1.625727177,0.76574886,1.3286312040000001,-3.917324789,-4.013838951,-3.549087105,-3.5842398,-4.237189438,-4.202268654,-3.915683562,-3.276713795,-1462.301739607472 -545,545,G52R,-0.0123626,0.021081446,0.014971346000000002,-0.381886376,-2.0423797009999998,-0.01646359,-0.025800267,0.001075068,-0.020902981,0.057772347,-0.015609455,0.00910685,0.020835841,-0.205480352,-0.5582924,-1.667269668,-2.417489733,1.260084795,1.364649007,-4.735410483,-4.36916066,-4.4029808269999995,-4.0396805339999995,-5.053335434,-5.811894959,-4.347794545,-2.95190814,-1459.5953438179567 -546,546,G52T,-0.028814535,-0.014915852,-0.011225543000000001,-0.149252886,-1.727659998,-0.00919026,-0.065441242,0.007812173,0.009218691999999999,0.010990568999999999,-0.040822273,-0.024792257999999998,0.0023411729999999998,-0.063936415,-0.234569357,-1.599645636,-1.855674359,0.7800788329999999,1.3204223999999998,-5.1912630889999996,-4.556334015,-4.239205193,-4.469777046,-5.071033997,-7.619965195,-4.898574967,-3.709303017,-1459.245602347888 -547,547,G52W,-0.042030153,-0.024696265,0.002043834,-0.623120863,-1.9843524780000001,0.036422099,-0.035813557999999995,-0.048246748,-0.019851473999999997,-0.049908274,0.0005157440000000001,-0.01428512,0.018372786999999998,-0.456534073,-0.789707652,-1.7909090930000002,-2.177795862,1.662455749,1.427692661,-8.232757307,-7.30501619,-7.8956138,-7.885926544,-8.177372948,-9.899857056,-7.095832497000001,-6.474529788,-1463.2717509306967 -548,548,G52V,-0.02586983,-0.010626934,0.028371197999999997,-1.416511474,-2.3233428640000002,-0.002087798,-0.038720869,-0.013018791000000002,-4.26e-05,0.014627688,-0.035881556,-0.019867877,0.07661027200000001,-1.290748217,-1.542274731,-1.989109539,-2.6575761890000003,2.623708565,1.7791195919999998,-7.390353557,-6.924515152000001,-6.261839012,-6.462740662000001,-7.175654076,-10.12701888,-6.929398357,-5.708914425,-1461.510058469139 -549,549,G52Y,-0.108321779,-0.060638248,-0.0009318839999999999,-0.38002932100000003,-2.109773078,-0.0033032829999999997,-0.125178942,-0.091464615,-0.050877544000000004,0.020117239,-0.141393734,0.049043080999999995,-0.050906848,-0.18602398899999997,-0.574034652,-1.486941356,-2.7326048,1.246786733,1.389292094,-8.075219528,-6.914054939,-8.008847435,-7.948563652000001,-7.730641968,-9.773989647,-7.288614875,-6.389109022,-1462.445827148389 -550,550,K53A,-0.009480222,0.001371396,0.009175101,0.020797248,-0.009332043,-0.012781208,-0.004421919,-0.014538525,-0.010372865,0.023404774,-0.020661982,0.029755544,-0.011405343,0.011598056,0.02999644,0.022921597000000002,-0.041585683,1.120589182,2.633820608,-1.677988852,-1.7659964680000002,-1.013070175,-1.538630867,-2.558896904,-1.5133498459999999,-2.764899118,0.296810672,-1466.4994395808317 -551,551,K53C,-0.054359667,0.01147139,-0.030007354,0.025694929,-1.3827770819999998,0.07859433,-0.052589045,-0.05613028900000001,0.103453299,0.028625262000000002,-0.005682483,0.019109233,-0.07912394,0.023166858,0.028222999,-1.08560626,-1.679947904,1.0081043570000001,1.397465929,-6.848581253,-6.000081024,-6.299377419,-7.334269577000001,-7.567601882999999,-7.041576363,-7.3468452420000006,-5.379504032000001,-1465.8803536030464 -552,552,K53E,-0.057326985,-0.022193405,-0.038447907,-0.038052717,-0.017441508999999997,-0.0064613,-0.072598768,-0.04205520099999999,-0.014469506000000002,-0.033112007,-0.011274801999999999,-0.041761365,-0.035134448,-0.045652713,-0.03045272,-0.006527651999999999,-0.028355365,1.0656663659999999,2.623297486,-2.0756151000000003,-1.912175842,-1.4800440830000001,-3.154644844,-2.446250992,-1.38495974,-2.864317392,0.627909394,-1463.8916093828157 -553,553,K53D,-0.0077959019999999995,0.0016050779999999998,0.035474456,0.041011577,0.013371071000000002,-0.018466342,-0.0077972169999999995,-0.0077945869999999995,0.005293256,0.033207337,-0.029997181,0.023242207999999997,0.047706704,0.019959189,0.062063965,0.036301312999999995,-0.009559172,1.259491033,2.8930176839999997,-3.6719566969999997,-2.468883987,-2.6495519869999997,-5.173734314,-4.975590034,-3.092023163,-4.119900862,-0.024595093999999998,-1462.965912737418 -554,554,K53G,-0.041356335,0.01232886,0.02294722,0.032055247,-0.093902637,0.026207282000000002,-0.03984317,-0.042869499000000005,0.034754131,0.050752205999999994,-0.026094486,0.056006943,-0.010112503,0.064342016,-0.000231522,-0.030476666,-0.157328608,1.237023233,2.517427644,-4.675491692,-3.639215332,-3.94985183,-6.313111641,-5.794354706,-3.68092495,-4.650691053,-0.9977324740000001,-1456.4041187814437 -555,555,K53F,0.013198544,-0.00199763,0.024897989,-0.007659326,-0.136761276,0.013997776000000002,0.047869068,-0.021471981,-0.020465021,0.020812491000000002,-0.02480775,0.055591447,-0.00579547,-0.017910577,0.002591926,-0.09609753,-0.17742502100000002,1.3339214,2.2679830880000003,-3.9357891510000003,-2.528354019,-3.14685318,-4.237520851,-5.894870804,-3.8713469010000003,-4.366818806,-1.6743139530000002,-1462.7891089837067 -556,556,K53I,-0.059441727,0.007738123,-0.009421033,0.015696018,-0.082011237,-0.033641695,-0.08811808300000001,-0.03076537,0.053599258,0.025798899,-0.010322653000000001,0.018454627,-0.037296692,0.044932335999999996,-0.0135403,-0.017492817,-0.14652965699999998,1.213423602,2.543383438,-3.391903246,-2.93918425,-2.9056680760000004,-4.189300483999999,-4.680452446,-2.244910973,-4.805919927,-2.19597829,-1466.7145125274546 -557,557,K53H,-0.065100628,-0.039347872,-0.02010982,0.010362261,-0.066030242,-0.028571457,-0.078964468,-0.051236788,-0.037413018,0.026769837999999997,-0.105465581,0.037938475,-0.078158114,0.021051092999999996,-0.000326571,0.022568928999999998,-0.154629412,1.139088154,2.66526459,-3.233080808,-2.9315330889999998,-3.3338094710000004,-2.617027153,-3.220897263,-4.062137062,-4.464857084,-1.617228506,-1461.8291389332153 -558,558,K53M,-0.056733005999999996,0.017320323999999998,0.029322215,0.016302163999999997,-0.025403977999999997,-0.053304177,-0.062466017,-0.050999995,-0.019572908,0.094394415,-0.059753768,0.08794017400000001,-0.029295744,0.043990047000000004,-0.011385718999999999,0.08045969,-0.131267646,1.223759613,2.920356167,-3.3038416930000003,-2.5613128130000002,-3.458778595,-2.699389992,-4.230004951000001,-3.569722115,-4.881024965,-2.7270557460000004,-1464.9901483431458 -559,559,K53L,-0.02775355,-0.007413932,0.008486077,0.031747423,-0.033696514,0.0017240729999999998,-0.026813952999999998,-0.028693146,-0.004239953,0.040714184,-0.055542047000000004,0.023775862000000002,-0.006803709000000001,0.041597233,0.021897613,0.014348283,-0.081741311,1.205919363,2.667881045,-2.297924609,-1.143322121,-2.323057243,-1.943709984,-3.252626701,-2.826906998,-4.010577778,-1.255735608,-1464.5942028872669 -560,560,K53N,0.035642862000000004,0.018168551,0.045629047,0.046970097999999995,0.000860667,-0.01870789,0.034037063,0.03724866,-0.08049769,0.019265653,0.017071448,0.042980804000000004,0.048277289,0.021153968,0.072786227,0.024485302,-0.022763969,1.0749744890000001,2.575935085,-2.397261484,-2.125000214,-2.067987778,-2.957359573,-2.22665036,-2.609309494,-3.156693437,-1.196900902,-1461.8749341685325 -561,561,K53Q,-0.064467582,-0.040891209,-0.015934848,0.008586940999999999,-0.035956316,-0.017645888000000002,-0.06853149,-0.060403674000000004,0.010390316,-0.014352789,-0.067429629,0.045118060999999994,-0.07698775599999999,0.041913921,-0.024740039,0.026126846000000002,-0.09803947800000001,1.108603588,2.726266873,-0.352964899,-0.344955299,-0.733219315,-0.041185318,-0.50551049,-0.13995407099999999,-0.834224945,-0.085470368,-1465.5800856985152 -562,562,K53P,-0.07645650799999999,-0.014814131999999999,-0.516393098,-1.6302705309999999,-2.375736807,0.051281823,-0.057169639,-0.09574337599999999,0.01044026,0.019469808,-0.049098072,-0.352982313,-0.6798038820000001,-1.494469414,-1.766071648,-1.7736835180000001,-2.977790096,3.5697699430000003,2.5835880159999998,-3.86512625,-3.395563881,-3.914318626,-3.7480929410000003,-4.097907967,-4.169747833,-4.229257076000001,-1.606272485,-1455.6177574591711 -563,563,K53S,-0.050495171,-0.013098143000000001,-0.005297299,0.035675001,-0.070319479,0.027581112999999997,-0.054754125,-0.046236217,0.015286283000000001,0.023627841,-0.049824127,0.047895201,-0.058489797999999996,0.063364246,0.007985755,0.008632441,-0.149271398,1.071761897,2.58014253,-2.438742757,-2.611211914,-1.701146332,-2.925926697,-2.755948723,-2.1994801180000003,-3.2078085260000004,-0.987376957,-1462.2675838521682 -564,564,K53R,-0.033126552999999996,-0.005835707,0.018994185,0.034880002,-0.020171097,-0.007097472,-0.053460442999999996,-0.012792663000000001,0.029693907999999998,0.037751621,-0.049423034000000005,0.07115291900000001,-0.03316455,0.058622479000000005,0.011137524,0.049797002,-0.09013919599999999,1.154307607,2.8306437160000004,-1.232863437,-0.42022381600000003,-1.050185966,-0.747173271,-1.543588943,-2.403145187,-2.343706802,0.852563508,-1461.4795989780687 -565,565,K53T,-0.047720099999999994,-0.018620372,-0.019365818,-0.004198577,-0.06812083,-0.018669861,-0.057383874,-0.038056325,0.074071227,-0.011596041000000001,-0.025644702999999998,0.009812796,-0.048544431,0.004545693,-0.012942846000000001,-0.028857027,-0.107384632,1.254800696,2.432989606,-1.973463837,-1.965676559,-1.420248367,-2.254488731,-2.4254802090000003,-1.801425316,-3.306855543,-0.7259684940000001,-1465.2094846642576 -566,566,K53W,-0.05888709,-0.030869081,-0.028850659,-0.004639882,-0.735453025,0.043709099,-0.050507579000000004,-0.06726660000000001,-0.029797219,-0.00557943,-0.056158732,0.030685649,-0.088386967,0.027871359,-0.037151122,-0.44310342,-1.02780263,0.824814215,1.5055091180000002,-1.656783841,-0.144984749,-1.519902435,-1.867578491,-2.889898605,-1.861554924,-3.88859761,-1.086243327,-1461.9685284337029 -567,567,K53V,-0.07460498,-0.014389252,-0.005017852,0.016363482,-0.041850368,-0.015458567,-0.077946146,-0.071263813,0.048483529000000004,0.045191863,-0.073970367,0.067571733,-0.077607436,0.058003611,-0.025276648,0.033740572,-0.11744130800000001,1.230449126,2.728448111,-2.64824884,-2.044095978,-2.233257408,-2.8145612410000003,-4.28724659,-1.862082985,-3.72701349,-1.313983913,-1468.5981377316639 -568,568,K53Y,-0.046545851,0.012037013999999999,0.031077342,0.040895084,-0.14182017800000002,0.072669371,-0.034756429,-0.058335273,-0.027235548,0.034548816,-0.010474789,0.073665232,-0.011510548,0.062659527,0.01913064,-0.095741332,-0.187899024,1.215013415,2.290331455,-4.683560483,-3.4600743260000004,-4.132097336,-4.862936409,-6.263318732999999,-4.69937561,-4.789992664,-2.160102434,-1458.0336396982893 -569,569,I54A,-0.023129063,-0.006890236,-0.0057679540000000005,0.04632831,-0.29747840000000003,0.033000292,-0.012215021000000001,-0.034043104,-0.012621712,-0.006911293000000001,-0.006869178,0.013762576,-0.025298482999999997,0.068074969,0.02458165,-0.199563203,-0.39539359700000004,1.250853078,2.066913331,-2.267246861,-2.957902466,-3.077179306,-1.328187683,-2.018848045,-1.954116806,-2.542771461,0.383157929,-1462.8198508778587 -570,570,I54C,-0.040677477999999996,-0.03869697,-0.031557142999999996,-0.012448513000000001,-1.22733725,0.022304435,-0.030096058999999998,-0.051258897000000005,-0.037283641,-0.047872767000000004,-0.029521172000000002,-0.025268087999999998,-0.037846198,0.017022248,-0.041919274,-0.9667439040000001,-1.487930595,0.804785647,1.3726316719999998,-4.805729349,-4.977004958999999,-5.5922477420000005,-3.9471438830000003,-5.109667084,-4.402583076,-4.537176366000001,-1.941919415,-1460.8396414867602 -571,571,I54E,-0.038754576,-0.01499376,-0.00151274,0.027136531000000002,-0.395029678,0.023081891,-0.02421874,-0.053290412,0.068783407,0.002231621,-0.032219141,-0.00012355799999999998,-0.0029019209999999996,0.06722057299999999,-0.012947512,-0.27491695,-0.515142405,0.743402718,1.5591557809999999,-1.833488882,-1.144862564,-2.6245727690000002,-1.1226017529999999,-1.3315403140000002,-2.9438670119999997,-2.8580017580000003,1.3631383769999998,-1462.897765217349 -572,572,I54D,-0.056099368,-0.007939577,-0.021386905,-0.09972308699999999,-1.6067735109999999,-0.021766659,-0.037656155,-0.074542581,-0.008375658000000001,0.014390567,-0.03026972,0.003933364,-0.046707174000000004,0.021273647000000003,-0.220719821,-1.604337277,-1.6092097440000002,0.601184374,1.309185605,-4.692432782,-4.318589478,-6.501045753,-3.7665638280000002,-2.819447647,-6.0565172039999995,-4.568761098,-1.347296878,-1459.7969769788906 -573,573,I54G,-0.064542125,-0.014153108000000001,-0.020052259,-1.2325033140000001,-2.112324616,0.045723955999999996,-0.029550329,-0.09953392,-0.033256371,-0.024280022000000002,-0.004026194,-0.018590146999999998,-0.021514371,-0.9391246459999999,-1.525881981,-1.9782857059999999,-2.246363526,2.2071254319999998,1.559193934,-3.690598213,-4.386127693,-4.941524788,-2.67427462,-2.8781355210000004,-3.572928444,-3.56936914,-0.724411576,-1460.1145681580529 -574,574,I54F,0.015921842,0.021441281,0.034468634,0.052441101,-0.063526157,-0.026463137,0.021186947999999997,0.010656736000000002,0.007404911,-0.035732059,0.07861462,0.005349171999999999,0.063588096,0.08258377900000001,0.022298422999999998,-0.074300618,-0.052751695,1.4113049519999998,2.545440026,-3.708910501,-3.58673307,-4.461830566000001,-3.2909434510000004,-3.84006131,-3.3649841080000003,-4.16432868,-1.1836828959999999,-1460.3113270029426 -575,575,I54H,-0.031823121,0.037092671,0.0009152160000000001,0.073679167,-1.122305108,-0.016733451,-0.022512675,-0.041133566,0.029778062999999997,0.11167706300000001,-0.037491722000000005,0.055062555,-0.053232123,0.147215269,0.000143065,-0.9197487540000001,-1.324861462,0.482941623,1.3387003,-4.540031844,-4.0541984630000005,-5.132406357,-3.9160394210000002,-4.330929718,-5.266585258,-3.299079692,-0.7391240840000001,-1460.3173391669989 -576,576,I54K,-0.054961239,0.017675841,-0.005080623,0.046059257,-1.522346732,0.050857354,-0.010579405,-0.09934307199999999,0.081414483,0.021503731,0.013847951,0.045432784000000004,-0.05559403,0.089636447,0.0024820660000000002,-1.260824181,-1.783869282,0.667896291,1.331573594,-2.8931396410000003,-3.948876595,-2.323361916,-2.456528549,-2.794453552,-2.942477592,-3.244820655,-0.37122574399999997,-1457.122764527332 -577,577,I54M,-0.002580459,-0.008294738000000001,0.021083792,0.022339234,-0.0029390379999999997,-0.047335045,-0.017696651,0.012535733,0.020596591,0.000889002,-0.017478478000000002,0.07424481,-0.032077227,0.073127598,-0.028449131000000003,-0.006186008000000001,0.000307932,1.155632099,2.637126711,-1.578486365,-1.949879761,-1.2697004170000001,-1.856499863,-1.445266449,-1.371085335,-2.713101529,-1.371446203,-1466.2786281923763 -578,578,I54L,-0.04230915,-0.026016007999999997,-0.014166538000000001,0.032575887000000005,-0.09729412400000001,-0.011744481999999999,-0.040702335,-0.043915965,-0.005682094,0.000416062,-0.052448077,0.026907332000000003,-0.055240407000000005,0.080893247,-0.015741474,-0.066205396,-0.128382852,1.201765173,2.357535951,-0.027791202999999997,-0.104934784,-0.068961151,0.14095536,0.128820366,-0.234835808,-1.361186622,-0.025450677,-1463.3805263629183 -579,579,I54N,-0.027288073,-0.0038368820000000002,0.017648614,0.036042556,-1.6807095969999999,0.017065763,-0.015296158999999998,-0.039279986,-0.015288952,-0.028626322000000003,0.020952559,0.065891453,-0.030594226000000002,0.11125923,-0.039174118,-1.591052382,-1.7703668119999998,0.456891098,1.306335875,-3.873269955,-3.7058824919999998,-4.78084462,-3.456992767,-2.525085762,-4.8975441360000005,-3.553138795,-1.060508641,-1459.5867580911145 -580,580,I54Q,-0.058182689,-0.032744167000000005,-0.0010353580000000001,0.037605257999999996,-0.8664619440000001,0.020938274,-0.055347837000000004,-0.06101754,-0.021254653999999998,-0.027866815,-0.037621518,0.010586818000000001,-0.012657533,0.052196677999999996,0.023013838,-0.574913876,-1.158010012,0.7451987659999999,1.433223734,-2.902590553,-2.931452034,-3.315317421,-2.3400285640000003,-2.390098625,-3.5360561219999997,-3.6157452589999997,0.107905765,-1465.0374182472005 -581,581,I54P,-0.044711657,-0.010474349,0.010979218999999998,0.030636418999999998,-0.9908001759999999,0.02849679,-0.039675768,-0.049747546,0.007678334,0.003458245,-0.024406942,0.048661647999999995,-0.02670321,0.083699466,-0.022426627999999997,-0.7688141559999999,-1.212786196,0.703797837,1.38428326,-5.194536037,-4.761108719,-5.4212813870000005,-4.886559425,-5.509677406000001,-5.394053246,-4.795443756,-1.303730615,-1462.1176345599815 -582,582,I54S,-0.081304748,-0.019553986000000002,-0.025621694,0.007173218,-1.302305709,0.022727181000000003,-0.072305048,-0.090304447,0.08487242800000001,0.019342173,-0.058450144,0.020961979,-0.07220536599999999,0.09607506,-0.081728625,-1.095735628,-1.50887579,0.8359607929999999,1.365554163,-1.984482954,-2.003571884,-2.631519249,-1.599689621,-1.59644532,-2.0911886980000003,-2.195178775,1.001114195,-1463.3600260331295 -583,583,I54R,-0.070541357,-0.022241652999999997,-0.015986349,0.022199842,-1.209600931,0.015964767,-0.043472893,-0.09760982,-0.037402063,0.005488925,-0.04997223,0.042616905,-0.074589603,0.090810106,-0.046410422,-0.787272462,-1.6319294,0.476593724,1.3461328769999998,-2.6785150730000002,-2.7120962680000003,-2.7629399489999997,-1.8107046740000001,-3.083763298,-3.023071175,-2.777154354,0.791897016,-1457.081047992222 -584,584,I54T,0.00801054,0.000297606,0.01587093,0.065095842,-0.017431717,-0.004542954,0.000210475,0.015810604,-0.020010752,0.008671234,-0.008076021999999999,0.016806019,0.014935841000000002,0.077923265,0.052268419,-0.029351006000000002,-0.005512428000000001,1.361151851,2.6363844690000002,-0.68440593,-1.317123375,-1.944217659,0.356044594,-0.24418115199999998,-0.272552055,-1.7184457469999999,1.797220981,-1464.8211586857215 -585,585,I54W,-0.148268344,-0.030851699,-0.03509277,0.023610867999999997,-0.33586407,-0.01612227,-0.059334843,-0.237201844,0.0072420769999999995,-0.019170533,-0.042532864000000004,0.006036301,-0.076221841,0.058713405,-0.01149167,-0.232936559,-0.43879158100000004,1.3275259959999999,2.026920352,-4.834102219,-4.479171043,-6.1401099089999995,-3.8614246060000004,-4.615488319,-5.074317215,-4.2255681339999995,-1.918368784,-1460.8033348913305 -586,586,I54V,-0.020032888000000002,-0.002041864,0.025395617000000002,0.068283713,0.054009757,-0.01513863,-0.034581529,-0.005484246999999999,0.0034480440000000004,0.02362648,-0.027710207,0.082294178,-0.031502944,0.12558349800000002,0.010983927,0.08465570900000001,0.023363804,1.1275347009999999,2.9638930930000003,-0.106620937,-0.059003799,-0.536916435,0.256526619,-0.192865402,-0.000845665,-1.7890680819999998,0.40249451299999994,-1464.2980848783627 -587,587,I54Y,0.0008938660000000001,0.000170567,0.041784093,0.05155287099999999,-0.862369383,-0.047665091,-0.008414305,0.010202036,0.02026095,0.033811189,-0.033470055,0.100694486,-0.017126301,0.108501919,-0.005396176999999999,-0.668245723,-1.056493042,0.477423959,1.360606119,-4.615511594,-4.280406967,-5.684105682,-3.988009659,-4.415904877,-4.709130783,-3.519965169,0.070656499,-1458.2438067323528 -588,588,L55A,-0.043946162000000004,-0.000406832,-0.017659964,-0.04864870599999999,-1.6201674590000001,-0.018545564,-0.022917889,-0.064974435,0.032860316,0.02843301,-0.029246674,0.001784491,-0.037104418,-0.016624178,-0.080673233,-1.423148544,-1.8171863730000002,0.7382433629999999,1.332343679,-3.4091377819999997,-2.092425934,-6.364892265,-3.681854874,-2.750774101,-2.155741737,-3.549245343,-1.0053076570000001,-1468.0281516588293 -589,589,L55C,0.028029462999999998,0.001886246,0.002193797,-0.00701446,-1.470231069,0.048476978,0.06000908,-0.003950154,0.014303419,-0.05532243,0.059094922,0.052632139,-0.048244546,0.062222867,-0.076251787,-1.393185321,-1.5472768159999999,0.247100085,1.304887879,-6.663730322,-6.1453296129999995,-7.441542168,-7.006262711000001,-5.6897113720000005,-7.035805748,-5.63049685,-3.7217091410000003,-1467.30240973318 -590,590,L55E,-0.078308734,-0.011803781999999999,-0.017035184,-0.062833403,-1.114443659,0.019067549,-0.08280446799999999,-0.073812999,0.072972759,-0.044920472,0.021312908,-0.011197608000000001,-0.022872759,-0.07971439999999999,-0.045952405,-1.00598219,-1.222905128,0.95321184,1.39677537,-6.569337236,-6.498293045,-8.704575347999999,-7.190007866,-5.440958405,-5.012851517,-5.185668956000001,-4.339928325,-1464.6878464114852 -591,591,L55D,-0.097568585,0.007447266,-0.009581961,-1.194058291,-2.571945359,-0.028671237000000002,-0.077885283,-0.117251887,0.039101927,0.019593289,-0.004698758,0.012425044,-0.031588966,-0.779251136,-1.608865445,-2.166373152,-2.977517565,1.839895064,1.374642484,-7.316120255,-6.170497795,-11.01929231,-7.7257506639999995,-5.85398597,-5.811074532,-5.712419656000001,-4.416674351,-1468.2308057122864 -592,592,L55G,-0.062744679,0.004591223,-0.002486328,0.009567455,-1.61012303,0.039326442999999996,-0.040691204,-0.084798153,0.024217107,0.018148048,-0.008965603,0.048985457,-0.053958112999999995,0.05550795,-0.03637304,-1.60504985,-1.615196209,0.554420618,1.3082232059999999,-7.622554494,-7.020751228,-9.847201842999999,-8.187922455,-6.942603996,-6.114292946,-6.166130805,-5.051864209,-1466.115580811631 -593,593,L55F,0.029728566,0.054367623,-0.018843382,0.0016532089999999999,-0.209352289,-0.02730735,0.030207291,0.02924984,-0.00044593599999999997,0.004441945,0.10429330099999999,-0.06297349299999999,0.025286728999999997,-0.053825168,0.057131585,-0.18810131,-0.230603267,1.495308765,2.191795125,-2.765576958,-2.179935318,-3.14322728,-4.269937363,-2.375571709,-1.85921312,-4.093077741,-0.618096223,-1463.3792711505666 -594,594,L55I,0.015801092,0.025449447000000004,0.017765421,0.038509523,-0.013824586000000002,-0.0004903290000000001,-0.012705896999999999,0.044308081,0.13521373,-0.06088898,0.11178787300000001,-0.011163983,0.046694824,0.015873963,0.061145082,-0.02845489,0.0008057180000000001,1.18803743,2.483375335,-2.124960611,-2.02143103,-4.005187439,-2.734849815,-1.3058075409999998,-0.557527229,-3.131091544,-0.09901524800000001,-1465.1736852703616 -595,595,L55H,0.01967476,0.024327373,0.034673711,0.011815338,-0.720452442,-0.002208673,0.05921104,-0.01986152,-0.027649987999999997,0.017525046000000002,0.031129699,0.06325662900000001,0.006090791999999999,0.029038291,-0.005407615,-0.510697338,-0.9302075459999999,0.522433189,1.390179118,-4.991145511,-3.741222977,-6.098104919,-6.061464691,-4.680322037,-4.37461293,-4.816604959,-3.581706595,-1466.3982784817927 -596,596,L55K,-0.016362383,0.062781488,0.066615652,-0.005006381,-0.8061271990000001,-0.006896957,-0.035483519,0.0027587540000000004,0.021047552,0.05680163,0.068761346,0.067074075,0.066157229,0.029550235,-0.039562996,-0.599181824,-1.0130725729999999,0.684510944,1.412167555,-7.41201237,-7.192982109,-9.069798279,-6.974298843,-6.025270821,-7.7977118,-7.04608472,-5.444832432,-1460.5694307261147 -597,597,L55M,-0.048998703,-0.017679516,-0.054487304,-0.027730247000000003,-0.067702575,0.030070307,-0.038735289,-0.059262116,0.18498755100000003,-0.0811261,0.045767068,-0.001968984,-0.10700562400000001,-0.039165036,-0.016295457,-0.014880276000000001,-0.120524873,1.1943883579999999,2.506278758,-3.580665215,-3.744216919,-3.848321495,-4.021985176,-3.430395683,-2.858406799,-4.156214179,-2.71152068,-1464.745856007561 -598,598,L55N,-0.004519032,0.047251744000000005,0.010384456,0.008009066,-1.5260329819999998,0.028973415,-0.0030450790000000004,-0.005992984,-0.012879236,0.054138411,0.040365077,0.032661058,-0.011892146999999999,0.013695243999999999,0.002322888,-0.949487822,-2.102578141,0.707327327,1.3600755430000002,-7.07943243,-6.9605602189999995,-8.420739624,-7.976489432999999,-5.883748665,-6.155624207000001,-6.339875677,-5.494911913999999,-1469.222365972586 -599,599,L55Q,-0.030800542,0.073817553,-0.011402408000000001,0.025562421000000002,-1.22558591,0.038036572000000005,-0.001181516,-0.060419568,-0.00729134,0.08708017900000001,0.060554927,0.039538207,-0.062343022000000005,0.020181424,0.030943417999999997,-0.8573665229999999,-1.593805296,0.8796129220000001,1.405673265,-5.237211339,-5.143525718999999,-6.653509102,-5.608140113999999,-4.085807777,-4.695073982,-5.20501748,-4.156817107,-1464.7327427496202 -600,600,L55P,-0.020048331000000003,-0.073588737,-1.459205261,-2.0948967119999997,-2.6049618430000003,0.024842976,0.025423424,-0.06552008599999999,0.022889362000000003,-0.043335947,-0.10384152599999999,-1.433859114,-1.4845514080000002,-2.059534637,-2.1302587859999997,-2.401333674,-2.808590012,2.9376147460000004,1.3539900180000002,-8.306996106,-7.403308128,-10.43497247,-7.890239769,-7.440086792000001,-8.366373367000001,-6.456354577000001,-4.046014867,-1456.8450547563843 -601,601,L55S,-0.065589886,-0.0031687259999999997,0.004811972,-0.030178609,-2.0217628519999997,0.001485089,-0.046266743,-0.084913029,0.01036546,-0.022642047999999998,0.016304596,0.035720926,-0.026096982999999997,0.004298917,-0.064656135,-1.523067271,-2.520458432,0.654592339,1.3169220590000001,-4.876852455,-4.213934975,-5.719207542,-6.152587685,-4.4469653319999995,-3.8515667419999997,-4.6263844480000005,-3.3798825910000003,-1466.1662658089772 -602,602,L55R,-0.010344306999999999,0.011764166999999999,0.028966117000000003,-0.007640521,-0.520211329,-0.004925605,0.00045368199999999996,-0.021142296,0.020842744,-0.0073620180000000006,0.030890351,0.049785939,0.008146295,-0.001863043,-0.013417999,-0.304533103,-0.7358895540000001,1.09015979,1.7443538809999999,-4.144089966,-3.55778981,-4.818662918,-4.186270409,-3.938962296,-4.218764397,-4.084569518,-3.903406227,-1457.214810112957 -603,603,L55T,-0.017072321,0.009161770999999999,0.004390845,-0.019588093,-0.997385307,0.005182841,-0.029033215,-0.005111427,0.011094963999999999,-0.012541387,0.030864929,0.020994421,-0.012212731999999999,-0.007400788,-0.031775397999999996,-0.586842842,-1.4079277719999999,0.8429768,1.453456549,-3.487301445,-3.175902016,-4.7275237269999995,-4.080710945,-2.831628395,-2.6207421419999997,-2.9034654460000002,-2.497732234,-1463.8420670325868 -604,604,L55W,-0.060346077000000005,0.047085735999999996,0.03714705,-0.014491091999999999,-1.28202634,-0.018202402,-0.07058695599999999,-0.050105198,-0.002847116,0.06603796599999999,0.028133506000000003,0.06257607700000001,0.011718023000000001,-0.024152102999999998,-0.004830081,-1.172978518,-1.391074161,0.521021073,1.3252469,-2.6874552869999997,-1.47247052,-4.4868185039999995,-2.8225795060000003,-2.637441612,-2.017966293,-2.797015375,-1.058120958,-1463.4401288670488 -605,605,L55V,0.014991166,0.081244323,0.060572757000000005,0.02313431,-0.049845220999999995,-0.004909117,-0.022182547,0.052164878,0.036503158,0.081558681,0.080929965,0.096029484,0.025116028999999998,0.016275226,0.029993394,-0.043165458,-0.056524984,1.3653693869999999,2.637889291,-2.595099638,-1.768907814,-4.709221512,-3.308373581,-2.097502167,-1.091493118,-2.271989622,0.353714244,-1465.9002804490738 -606,606,L55Y,-0.019376263,0.00380908,0.036430463999999996,-0.005424249,-0.120999362,-0.016813688,-0.027238701,-0.011513825,0.048041515,0.017675425,-0.010057266,0.063475005,0.009385922,-0.0077433630000000005,-0.0031051340000000003,-0.08477337199999999,-0.15722535099999999,1.272755985,2.290210922,-4.279370291,-3.188171608,-4.103879044,-5.847480469,-3.707082947,-4.550237388999999,-4.011470481,-1.385643533,-1460.1818352835253 -607,607,E56A,-0.007075149,-0.045329982000000005,-0.048318462,-0.013853826999999999,-0.087059359,-0.024787014,-0.019267115,0.0051168179999999995,0.15445273699999998,-0.055201609000000006,-0.035458355,-0.084661397,-0.011975527,-0.07102575,0.04331809599999999,-0.137520327,-0.03659839,1.411536598,2.222463606,,,,,,,,,-1462.8809071709402 -608,608,E56C,-0.105680933,-0.043289752,-0.104420778,-0.107748186,-1.5553789180000002,0.07930635,-0.10360573699999999,-0.107756129,0.033998367,0.007584677,-0.09416418,-0.082322322,-0.126519233,-0.063211844,-0.152284527,-1.485573511,-1.6251843240000001,0.8526084309999999,1.33210435,,,,,,,,,-1459.4132835594937 -609,609,E56D,0.049706364,-0.001656966,-0.02204443,0.01783075,-0.058707709000000004,-0.033508049,0.047752800000000005,0.051659928,0.012560391,0.01139915,-0.014713081000000001,-0.058771828,0.014682968000000001,-0.020242648000000002,0.055904148,-0.061992153,-0.055423265,1.440886626,2.531283859,,,,,,,,,-1465.0905852643773 -610,610,E56G,0.013852202,-0.037260837000000005,-0.04457583,0.022340571,-0.051919235,-0.014671097,0.004696482,0.023007922000000004,0.146940447,-0.045369904,-0.02915177,-0.10263316900000001,0.013481509,-0.019784094,0.064465236,-0.06930033599999999,-0.034538134,1.174965431,2.220837145,,,,,,,,,-1464.3614150015637 -611,611,E56F,-0.014309734,-0.022002683,-0.040042314,-1.272702414,-2.4408351880000003,-0.042179322000000005,0.00312856,-0.031748028,-0.021471825,-0.016889803999999998,-0.027115562000000003,-0.05630751,-0.023777118,-0.844470432,-1.7009343959999998,-2.320253123,-2.561417252,1.88586285,1.321685566,,,,,,,,,-1455.4376428569667 -612,612,E56I,-0.011515885,-0.047164517999999996,-0.045670434,-0.753472666,-2.18407722,-0.022711535,-0.009558315999999999,-0.013473454,0.0016950939999999999,-0.037919853999999996,-0.056409180999999996,-0.111194924,0.019854056000000002,-0.524001804,-0.982943528,-1.895568781,-2.472585659,1.7133016719999998,1.4071078190000001,,,,,,,,,-1457.6480884863995 -613,613,E56H,-0.070809657,-0.063213294,-0.092155841,-0.05192433900000001,-1.177880662,-0.0177034,-0.06433672,-0.07728259400000001,0.045289532,-0.007392224,-0.119034364,-0.061103452999999995,-0.123208229,-0.047572653,-0.056276025,-0.899108727,-1.456652597,0.752424048,1.376908649,,,,,,,,,-1459.4456500280648 -614,614,E56K,0.015647325,0.007614162,-0.020991929,0.011995589,-0.101755554,0.006501686,0.016416933999999998,0.014877715,0.048776654,-0.002774055,0.018002379,-0.029402852,-0.012581006,-0.05459101,0.078582188,-0.14131897699999998,-0.062192131,1.438046943,2.254842547,,,,,,,,,-1460.2518579708412 -615,615,E56M,-0.06796353599999999,-0.059961332,-0.067191928,-0.012326941999999999,-1.303131735,-0.003275111,-0.070221294,-0.06570577799999999,0.176413373,-0.009629253,-0.110293411,-0.08322919999999999,-0.051154656,-0.00150631,-0.023147574,-1.205562615,-1.400700855,0.8889784740000001,1.360993919,,,,,,,,,-1459.9780284501612 -616,616,E56L,-0.029492049,-0.028623201,-0.02261759,0.006626346,-1.3142741740000001,-0.006761121,-0.022822400000000003,-0.036161698,0.06423704400000001,0.006708924000000001,-0.06395532599999999,-0.034685753,-0.010549427,-0.014150613999999999,0.027403305,-1.023143044,-1.605405304,0.735594566,1.358527951,,,,,,,,,-1457.1151011004113 -617,617,E56N,-0.061491337,-0.099418736,-0.029372517999999997,-0.008609457,-0.101191244,-0.05807229,-0.083730081,-0.039252592999999995,0.055156435999999996,-0.045307234,-0.15353023699999999,-0.002892315,-0.055852720999999994,-0.010367395,-0.006851519,-0.078147535,-0.124234952,1.30780079,2.3325750419999998,,,,,,,,,-1465.1158548048697 -618,618,E56Q,-0.068666217,-0.070112779,-0.09635936,-0.033419067999999996,-0.13106595099999999,-0.042763784000000006,-0.074507563,-0.06282487099999999,0.11004822,-0.040794858999999996,-0.099430699,-0.10880083199999999,-0.083917887,-0.043994499000000006,-0.022843636,-0.126039188,-0.136092714,1.367618085,2.189172252,,,,,,,,,-1463.1179735371843 -619,619,E56P,-0.012698869,-1.267404922,-2.061123294,-2.326231925,-2.66658801,0.01438047,0.017659253,-0.043056990999999996,0.034611594,-1.152267954,-1.382541889,-2.257040859,-1.865205728,-2.032429493,-2.620034356,-2.5182805790000002,-2.81489544,0.24743072,-0.718369061,,,,,,,,,-1458.6806931360625 -620,620,E56S,-0.0007111330000000001,-0.017403851,-0.041781813,0.015782653,-0.092556475,-0.028021957000000004,-0.0073836480000000005,0.0059613819999999994,0.064406007,0.008578458,-0.04338616,-0.053848953,-0.029714672,-0.010584885,0.042150191,-0.099030323,-0.086082627,1.238890577,2.226796056,,,,,,,,,-1463.3753453535028 -621,621,E56R,0.011447021000000002,-0.006710533,-0.029918322999999997,-0.026677064,-0.221984209,-0.009670920999999999,0.027226742999999998,-0.004332702,0.027233921,0.009520699,-0.022941765,-0.040526953,-0.019309693,-0.049998792,-0.0033553359999999996,-0.22873327699999998,-0.21523514100000002,1.3376358940000002,2.005808318,,,,,,,,,-1456.192438845057 -622,622,E56T,-0.020475445,-0.038487431,-0.028395944,-0.0009677689999999999,-0.103973384,-0.08167141,-0.039240654,-0.001710235,0.067373955,-0.003981772,-0.07299309,-0.016308431,-0.040483457,-0.009082046,0.0071465090000000005,-0.08323749400000001,-0.12470927400000001,1.36053415,2.349029252,,,,,,,,,-1462.6291020037606 -623,623,E56W,-0.014720088000000001,-0.046734505999999995,-0.201240581,-0.649261405,-2.094695901,0.024715932000000003,0.026222512000000003,-0.055662687999999995,-0.011487603999999998,-0.144791744,0.051322732999999995,-0.30159364899999996,-0.100887512,-0.498586209,-0.7999366,-1.8472641019999998,-2.342127699,1.8957620309999998,1.487995674,,,,,,,,,-1453.9383277087472 -624,624,E56V,-0.04984681,-0.044497681,-0.042798562000000005,-0.001796628,-1.128714536,0.017311442,-0.038936269,-0.060757350999999994,0.070317786,0.000519606,-0.08951496699999999,-0.030148132999999997,-0.055448990999999996,-0.019360477,0.015767222,-0.960312342,-1.29711673,0.784033348,1.37230954,,,,,,,,,-1458.5181377525441 -625,625,E56Y,-0.043523652,0.025877865,0.017042042,-0.34963870799999996,-1.791599132,0.042423775999999996,-0.03035837,-0.056688933,0.059616927,0.046011240999999994,0.005744488000000001,-0.005103774,0.039187858,-0.26831350800000003,-0.43096390700000003,-1.745390669,-1.837807595,1.349598916,1.370011459,,,,,,,,,-1451.9412279687822 -626,626,S57A,0.036340484,-0.004586517,0.03007834,-0.000883725,0.025721015,0.031624471,0.016102774,0.056578194000000005,-0.035629375,-0.026064197999999997,0.016891164,0.0061413019999999995,0.054015377999999996,-0.01946162,0.017694171,-0.046749139,0.09819116800000001,1.3799258859999999,2.505310835,-1.377781865,-1.099274887,-1.993630531,-0.524309174,-1.127201965,-2.144492767,-2.7231057919999997,0.122921169,-1464.260005725082 -627,627,S57C,-0.115665714,-0.013955769,-0.051785959000000006,-0.057806418,-1.504226134,0.145683596,-0.072253158,-0.159078269,0.111166846,-0.050212967000000004,0.02230143,-0.011094171000000002,-0.092477747,-0.065923019,-0.049689817000000004,-1.27294584,-1.7355064269999998,0.916078152,1.357990546,-5.841583999999999,-4.677781075,-6.4557481,-5.122833244,-6.9841106029999995,-5.967446976000001,-6.178315284,-2.993184007,-1460.967452247627 -628,628,S57E,0.043007582999999995,-0.05173617900000001,-0.02321338,-0.024460533,0.005882297,0.051438362,0.095171462,-0.009156296,0.034711129,-0.106342874,0.002870517,-0.031076852999999998,-0.015349906000000002,-0.047930787999999995,-0.000990277,-0.054090072999999995,0.06585466599999999,1.457366753,2.562356699,-2.615928589,-1.282341995,-1.852585655,-3.476698189,-3.3186020810000003,-3.1494150239999996,-3.940574859,-0.838964677,-1469.8530855709687 -629,629,S57D,0.012117977,-0.025854207999999997,-0.014948584,-0.018968414,-0.976962278,0.144862333,0.027780004,-0.003544051,0.016151053000000002,-0.04325458099999999,-0.008453834,-0.057893672,0.027996505,-0.06153611,0.023599283,-0.661296904,-1.2926276509999999,0.8754014000000001,1.444372617,-3.4851503189999997,-2.612180962,-2.765914429,-3.857658485,-3.424132568,-4.76586515,-4.421185363,-1.068017849,-1467.2137822005898 -630,630,S57G,0.02325097,0.026386692000000003,-0.017013241999999998,-0.019903022,-0.036135834,0.076971864,0.026333981,0.020167958,0.048034275999999994,-0.052249883,0.10502326599999999,-0.041878833,0.007852349,-0.0497311,0.009925056,-0.08796653800000001,0.015694871000000003,1.353534257,2.300723294,-0.9383417940000001,-0.746865417,-1.29488813,-0.613921997,-0.63042868,-1.4056047440000001,-1.83041303,0.22230893,-1468.15208067419 -631,631,S57F,-0.00194961,0.013476406000000002,0.051840073,0.015182699,-0.258372422,0.008782859,0.016264959,-0.020164178,0.046427148,-0.0041582,0.031111012,0.053146407,0.050533739,0.02456273,0.005802668,-0.19523437899999999,-0.321510465,1.265665564,2.023197908,-5.73285892,-3.422742661,-5.787638306,-5.219929939,-7.156373909,-7.077609787,-5.429482613999999,-2.23125306,-1461.816813764628 -632,632,S57I,-0.039722372,-0.033439109,-0.039665635,-0.033138512,-1.225007314,0.087657125,0.030985571,-0.110430315,-0.13053019800000001,-0.052825847999999995,-0.01405237,-0.020779534,-0.05855173599999999,-0.053164275,-0.013112748,-1.1330645990000001,-1.316950029,1.062855707,1.4032063830000001,-7.176854854,-5.531678597000001,-8.303977844,-6.163407082000001,-8.382250053,-7.5029606929999995,-6.289185336,-3.797157595,-1459.305672749877 -633,633,S57H,0.010871542,-0.014677906000000001,-0.000915884,-0.007518133000000001,-0.200224732,0.031863932000000005,0.03318333,-0.011440246000000001,0.083583325,-0.017047206999999998,-0.012308603999999999,-0.043106757999999995,0.04127499,-0.015843753999999998,0.000807488,-0.164247487,-0.236201976,1.339313391,2.117806775,-4.453052979,-3.345781906,-4.532512665,-4.764303871,-4.443329887,-5.179336563000001,-4.356326686,-2.571637151,-1461.9653740692884 -634,634,S57K,0.031551834,0.015012525,-0.008086395,0.013220865,-0.040180196,0.049263309000000005,0.046846961,0.016256707,-0.001339926,-0.014531819,0.044556868,0.0033631190000000004,-0.019535909,0.00751213,0.018929599,-0.10380244300000001,0.023442051000000002,1.386744168,2.3977383530000003,-5.076596799,-4.708790337,-4.992588829,-4.516917068,-6.415753562999999,-4.748934196,-4.945336455,-2.548374021,-1458.5365218212828 -635,635,S57M,-0.091014005,-0.07920851,-0.039079847,-0.072252579,-0.128876766,0.048469955,-0.093113885,-0.088914124,0.049035021,-0.093529427,-0.06488759200000001,-0.055705927,-0.022453766,-0.039905012999999996,-0.104600144,-0.117889867,-0.139863664,1.507092754,2.379889094,-6.463851407999999,-5.368222946,-6.463892723,-5.281755821,-7.80404232,-7.401343231,-6.3925078310000005,-3.028457468,-1463.4838761510327 -636,636,S57L,-0.007037969,-0.008045191,-0.008061671,-0.010023526,-0.638674441,0.032398866,0.038249579,-0.052325515999999996,0.06271173599999999,-0.018508382,0.002418,0.0050217890000000005,-0.02114513,-0.015982155,-0.004064896,-0.45213098799999996,-0.825217894,0.920949279,1.5257893040000001,-4.97456615,-3.056441925,-4.656159263999999,-3.794424751,-7.705344902,-5.660459907999999,-4.680247137,-1.36518123,-1460.7361666238867 -637,637,S57N,-0.025358027,-0.017188854,-0.019736103999999997,-0.019631752,-0.340335844,0.045646190999999996,-0.0020494289999999997,-0.048666625,0.0624721,-0.011587857,-0.02278985,-0.01149832,-0.027973887000000003,-0.014710408000000001,-0.024553095,-0.232219919,-0.448451768,1.146066182,1.844217246,-3.282030991,-3.242335609,-3.457667831,-3.6026700519999997,-2.677920578,-3.429560883,-3.8422411430000003,-1.655055995,-1464.0204710350372 -638,638,S57Q,0.048736563,-0.029655163999999998,-0.032662049,-0.016072632,-0.014098500000000002,-0.023760242999999997,0.050507502,0.046965623,0.017934315,-0.077683923,0.018373596000000002,-0.03736447,-0.027959627999999997,-0.04862179,0.016476527,-0.053721881,0.025524882000000002,1.406656401,2.445028632,-3.380341451,-2.33595459,-2.9788419110000004,-3.705413445,-3.813675407,-4.067821899,-3.9372041810000002,-1.551160695,-1468.930325258989 -639,639,S57P,-0.039144589,-0.011819021,-1.32400264,-2.119650989,-2.61056601,0.051998947999999996,-0.007547331,-0.070741847,0.02570305,-0.00523472,-0.018403322,-1.1348285329999999,-1.5131767459999999,-2.161050864,-2.0782511130000003,-2.523598587,-2.6975334330000003,2.098460884,0.747681459,-8.57026028,-7.59972274,-8.839180573,-7.886295692000001,-9.588770103,-8.937332291,-9.233522517,-8.524726012,-1457.0275985281914 -640,640,S57R,-0.020317261,-0.026390838,-0.004827167,-3.63e-05,-0.129307108,0.064040284,-0.025159072,-0.015475448999999999,0.0040822490000000005,-0.014339355,-0.03844232,0.0010393919999999999,-0.010693726,0.017067651,-0.017140261,-0.12132630800000001,-0.137287907,1.341335418,2.224991218,-4.712526955,-3.7634872280000002,-4.760721443,-4.514400291,-5.750427795,-4.773598015,-4.84238626,-1.94624208,-1456.1168258190155 -641,641,S57T,0.005376946999999999,-0.018162997,0.003326203,-0.001019837,-0.065115516,0.024178547999999998,0.009672883,0.001081011,0.048341563,-0.030015497000000002,-0.006310496,0.023308462000000002,-0.016656056000000002,-0.052996614000000004,0.05095694,-0.10799016300000001,-0.022240869,1.4069967719999998,2.2977707919999997,-2.320858521,-1.8043583369999998,-3.126137726,-1.5666153790000001,-2.378113152,-2.729068008,-2.541281294,-0.821961756,-1463.3717515999451 -642,642,S57W,-0.035707871,0.010650808999999999,0.014304718000000001,-0.007609767,-0.495673855,-0.07535813599999999,-0.065090821,-0.006324921,0.03362802,0.024866068999999998,-0.0035644509999999997,0.031550084,-0.0029406479999999997,-0.0027950609999999997,-0.012424471999999999,-0.38251440700000006,-0.6088333029999999,0.8035321670000001,1.532618686,-8.917248959,-6.810054909,-9.489147163,-8.50209655,-10.20008459,-9.58486158,-8.325882829,-6.236506034,-1460.23741509486 -643,643,S57V,-0.052295892999999996,-0.013614678,0.0218317,0.016770773,-0.09729119,0.07702263599999999,0.012746252,-0.117338038,0.07914694,-0.034573968,0.007344613000000001,0.026772543,0.016890857,0.010089846,0.0234517,-0.12074590699999999,-0.073836472,1.353746715,2.270184497,-5.244703833,-3.643005608,-6.570448586,-4.323586739,-5.831363372999999,-5.855114861000001,-5.231396782,-2.1116017769999997,-1459.355141504202 -644,644,S57Y,-0.004951861,-0.002948246,-0.03655248,-0.02762638,-0.39567102299999996,0.002009097,-0.010081703000000001,0.000177981,0.020931024,-0.015919478,0.010022986999999999,-0.013956151000000002,-0.059148808,-0.046205009000000005,-0.009047751,-0.30132717800000003,-0.490014867,1.4649955959999998,2.025613534,-6.054247644,-3.4174666819999997,-6.3552256620000005,-5.651023262000001,-7.430377235,-7.417145378,-6.279595541,-2.683717596,-1459.2970117246732 -645,645,F58A,0.053703426,0.023405916000000002,0.0063174830000000005,0.043638360999999994,-0.096847901,0.037978173,0.035870629,0.071536222,-0.214490491,0.000774834,0.046036997999999996,0.005406816,0.00722815,-0.012274535,0.09955125699999999,-0.10341619099999999,-0.09027961,1.436732134,2.375580792,-3.6013236739999996,-4.760767685,-2.172290977,-4.741536133,-1.095916397,-5.236107178,-3.4126748999999994,-1.859468689,-1456.5135534820147 -646,646,F58C,0.075695117,0.1183562,0.025289073,0.096241539,-1.092346968,0.068389652,0.12328048400000001,0.028109749,-0.164393843,0.049370243,0.18734215699999998,0.027868082000000002,0.022710064,0.075846578,0.116636499,-1.2142463079999999,-0.970447628,0.5667302820000001,1.327073725,-4.0265188830000005,-4.7088513789999995,-2.9057226789999997,-3.825254005,-3.605151947,-5.087614403,-4.011841565,-3.7774965110000003,-1457.6999619053677 -647,647,F58E,0.031287255,0.03264178,-0.028907431,-0.660428802,-1.961057663,0.05576786,0.044749375,0.017825135,-0.144790998,-0.01923441,0.084517969,-0.055454698,-0.002360164,-0.35536655100000003,-0.9654910529999999,-1.946421665,-1.975693661,1.4962162030000001,1.361844319,-3.368897084,-3.902692886,-1.572657204,-5.056076889,-2.169550552,-4.1435078889999994,-3.204229822,-2.473618145,-1458.93379956251 -648,648,F58D,0.05737005,0.11386344300000001,-1.054667056,-1.816713315,-2.678411367,0.088615985,0.122826564,-0.008086464,-0.1467305,0.093683708,0.13404317699999999,-0.829809572,-1.27952454,-1.7902437569999998,-1.8431828719999999,-2.759267799,-2.597554935,2.1631619840000003,0.994874422,-4.8774362060000005,-6.1214145360000005,-2.91999427,-5.286204163,-3.901864677,-6.1577033839999995,-4.183316898,-3.227637785,-1458.1723418305628 -649,649,F58G,0.042318228,0.069921796,0.023864113,-1.0700427240000001,-2.34256389,0.055180123,0.054546448,0.030090007000000002,-0.194720119,0.019081443,0.12076214800000001,0.00796039,0.039767835,-0.600708877,-1.53937657,-2.1106877269999997,-2.574440053,1.6852524830000002,1.345426249,-5.984155087,-6.581969765,-3.553832542,-6.9792631,-4.7704098660000005,-8.035300162999999,-5.678218104,-5.147866598999999,-1453.98239683453 -650,650,F58I,0.065054418,0.071619853,0.037203604,0.04339302,-1.14552304,0.035935407,0.038936587,0.09117224800000001,-0.294190571,-0.015772413,0.159012119,-0.025114179,0.09952138699999999,0.036338037000000004,0.050448002,-0.9971439940000001,-1.293902086,0.716145415,1.3568031459999998,-2.464877974,-2.675883888,-4.2794480969999995,-2.5771159669999997,-2.23680085,-0.555141068,-3.00572788,0.999320566,-1461.9348273160867 -651,651,F58H,0.086669164,-0.000310913,-0.047290162999999996,0.025494098,0.026093905,0.039187741,0.083113652,0.09022467599999999,-0.178163608,-0.10276575800000001,0.10214393199999999,-0.123287425,0.028707099,-0.09938977,0.150377965,-0.066018359,0.118206169,1.3823330440000001,2.369509033,1.241556398,1.279864029,2.7687402189999997,1.369929222,1.156203423,-0.36695490299999994,-0.7702133259999999,1.103905254,-1461.935998226516 -652,652,F58K,0.057462835,0.11377443,0.059767707,0.121973303,-1.6374602880000002,0.055411401,0.08468631300000001,0.030239357,-0.268232033,0.082479151,0.145069709,0.077728852,0.041806561,0.113479114,0.130467491,-1.498997603,-1.7759229730000001,0.580756037,1.314514043,-2.973144965,-3.316693634,-0.12025032,-5.144599617,-3.1194090039999995,-3.1647722469999997,-3.782699628,-1.960582425,-1460.9558249772526 -653,653,F58M,0.042891017000000004,0.064612983,-0.002764882,0.071615347,-0.179274328,-0.0055063840000000005,0.022457313,0.06332472,-0.26702333300000003,0.07208642900000001,0.057139536,0.008651723,-0.014181486,0.056058984000000006,0.08717171,-0.167584979,-0.19096367600000003,1.2152938,2.077279764,-3.6472431380000003,-3.7751538769999997,-4.139557571,-3.329104355,-3.3475749589999997,-3.6448249280000002,-3.309712984,-1.89479711,-1462.536776858382 -654,654,F58L,0.038395635,0.058953150999999995,0.018928703999999998,0.091389396,-0.46302966799999995,0.039074454,0.045157203,0.031634066,-0.150842194,0.014960128,0.102946174,0.05631289900000001,-0.018455491,0.078681844,0.10409694800000001,-0.289322433,-0.636736902,0.629248339,1.523176922,-2.291952379,-2.358106621,-3.015200539,-1.3157820279999999,-2.5256450040000002,-2.245027702,-2.6380409730000003,0.372004069,-1463.395030892454 -655,655,F58N,0.06750790599999999,0.071273244,0.036423784,0.119450076,0.020832937,0.004742411,0.044497905,0.090517906,-0.16243723,0.056974479,0.085572008,0.005013556,0.067834011,0.06381390299999999,0.17508624899999997,0.050482438,-0.008816565,1.1517464929999999,2.8489480910000005,-1.839786748,-2.3987015,0.309981918,-2.393475304,-2.0218022159999998,-2.694936638,-1.9959373809999998,-2.175855606,-1459.081654804293 -656,656,F58Q,0.02762736,0.052770797,0.010679443,0.042182075,-0.396714012,0.030971119,0.03494434,0.020310379,-0.21388601699999998,-0.005603581999999999,0.111145176,0.005901285,0.015457601000000001,0.009050524,0.075313625,-0.2698851,-0.5235429229999999,1.5405768690000001,2.131264544,-1.839245314,-1.20944281,-0.144272171,-2.635814644,-1.509096504,-3.697600441,-1.941657243,-1.820499462,-1459.991270011291 -657,657,F58P,0.025621697000000002,-1.655874927,-2.136885028,-2.19248557,-2.953853896,0.078188883,0.053294155,-0.002050761,-0.30651538300000003,-1.794212229,-1.517537624,-2.221950925,-2.05181913,-2.210098098,-2.174873041,-2.8603633760000005,-3.047344416,0.139921894,-1.2160799740000001,-6.839248616,-7.076975432999999,-5.561164597,-7.385935989,-5.734165955,-8.438001106,-6.528542936,-6.7661445879999995,-1456.712184802629 -658,658,F58S,0.030074318,0.042791256,-0.009680112,0.075776546,-0.12386197300000001,0.014903401,0.025583561,0.034565075,-0.19837834,0.009620063,0.075962448,-0.00177636,-0.017583863999999998,0.043656729000000005,0.107896362,-0.092954131,-0.154769815,1.290096231,2.319377947,-2.401836443,-3.9146939769999998,-0.335484695,-3.1783417430000003,-1.068517494,-3.512144302,-2.760671447,-1.880404534,-1455.6239606351592 -659,659,F58R,0.021534511,0.035974862999999996,0.005343663,0.063960018,-0.371947743,0.031782736,0.023285645,0.019783376000000002,-0.19464223100000003,0.027035007000000003,0.044914719000000006,0.022990762999999997,-0.012303437,0.059738770999999996,0.068181265,-0.26909844,-0.474797046,1.538419356,2.091996821,-1.855895274,-1.2799820179999999,-0.815947968,-1.655229279,-2.0418289869999997,-3.4864881210000003,-1.7465253109999999,-0.7896788379999999,-1457.0060596433468 -660,660,F58T,0.016727221,0.032433079,-0.049513800000000004,0.060836745,-1.4008211919999998,0.05151606,0.017421324,0.016033117,-0.17345650199999998,-0.020093991999999998,0.084960149,-0.035475117,-0.06355248299999999,0.012890631000000001,0.10878285900000001,-1.127951885,-1.673690498,0.6546796779999999,1.339868359,-3.58893017,-3.8008980639999996,-2.491179779,-4.2855116419999995,-2.258207703,-5.108853661,-3.337422292,-2.518604133,-1457.5997167965397 -661,661,F58W,0.097898921,0.073112629,0.051253868,0.090480436,0.038062554,0.044609526,0.10926005800000001,0.08653778300000001,-0.23036857800000002,0.026480551,0.11974470599999999,0.041909859,0.060597877,0.064960586,0.116000286,0.038220252,0.037904856,1.226956051,2.8425728360000004,0.165649355,-0.6207332,1.7372446819999998,0.123624969,0.25748485600000004,-0.669374535,-0.419325534,-0.09920534,-1463.6858810256235 -662,662,F58V,0.028692807,0.074743462,0.040002758,0.113965939,-0.33502622,0.049219720999999994,0.022135064,0.035250549,-0.210415734,0.06868779700000001,0.080799126,0.08699119300000001,-0.006985676999999999,0.125852455,0.102079423,-0.208481253,-0.46157118700000005,1.2415502,2.0106484769999997,-2.256215257,-2.131777954,-3.728735435,-2.3018727340000003,-1.128338425,-1.9903517380000002,-2.05145733,0.6078729270000001,-1460.549591650255 -663,663,F58Y,-0.022005373999999998,-0.004815293,-0.027550576,0.088073872,-0.020413011000000002,0.106657252,-0.003327738,-0.04068301,-0.165576783,-0.09519972800000001,0.08556914199999999,0.006941694,-0.062042846,0.025818304,0.15032944,-0.073284113,0.032458091,1.2199872859999998,2.328097342,2.810577368,1.907713646,3.8485631710000003,3.1970737610000004,2.733170494,2.366365768,1.631268395,1.278645988,-1462.9449124131352 -664,664,R59A,-0.042590036,-0.009806075,-0.014219912,-0.299772351,-1.9451652730000002,0.02673729,-0.009590043000000001,-0.075590029,-0.053517282,0.029697942,-0.04931009099999999,-0.001746285,-0.026693538,-0.136592425,-0.462952277,-1.7045823619999998,-2.185748184,1.099183575,1.3462331230000002,-7.037316512,-6.472022644,-7.287424758999999,-7.158469475,-6.188660515,-8.080005165,-5.888180525,-3.1289143439999996,-1458.2116334410384 -665,665,R59C,-0.024958553999999997,0.004552714,-0.031984195,-1.026452236,-1.573662471,0.036745006000000004,0.031450621,-0.081367729,-0.029718634,-0.015187495,0.024292922,-0.024518187,-0.039450202000000004,-0.9129163779999999,-1.139988094,-1.409979551,-1.73734539,3.225896783,2.657104414,-10.57249205,-9.747202705,-10.35273053,-11.24563578,-10.0832047,-11.43368652,-8.717475851,-6.657244455,-1456.6599651337601 -666,666,R59E,-0.061230755,0.070267371,-0.714981819,-1.75309971,-2.998283498,0.021716548999999998,-0.04198176,-0.080479749,-0.04908726099999999,0.041814639,0.098720103,-0.47639455399999997,-0.953569083,-1.566438108,-1.939761311,-2.594980198,-3.4015867969999998,1.7822807719999998,0.914195358,-7.942248407,-7.840119385,-7.893029816,-8.707571236,-6.562027802,-8.708493797000001,-6.546616016000001,-3.047025845,-1458.8361510089599 -667,667,R59D,-0.065755847,-0.022956355,-1.238107865,-1.901520979,-3.24264753,0.074673979,-0.007084544,-0.124427149,0.054712038,-0.011067118,-0.034845591,-0.9858721840000001,-1.490343545,-1.754935515,-2.048106443,-2.850424395,-3.634870665,2.38602495,1.117118587,-6.95260229,-6.777798676000001,-7.395041908,-7.378039436,-6.181769492999999,-7.0303619379999995,-5.667329775,-1.8973460819999999,-1459.1377513143234 -668,668,R59G,-0.100110431,0.001586835,0.0054936590000000006,-1.3972910369999998,-2.30278815,0.045180952999999996,-0.068039856,-0.132181005,-0.016586963,0.06292102299999999,-0.059747352999999996,0.033749461,-0.022762143,-1.102850864,-1.691731209,-2.388957256,-2.216619043,0.8084454179999999,0.752590434,-6.733596417,-5.96677668,-6.864717995,-6.253848686,-6.3564118579999995,-8.226226868,-6.005111808,-1.951926051,-1461.104027939029 -669,669,R59F,0.02912799,0.131202627,-0.8770012220000001,-1.75491193,-2.7694322239999996,-0.048511577,0.08382446,-0.025568481,0.011266968,0.146474049,0.11593120400000001,-0.560760894,-1.19324155,-1.486947645,-2.022876214,-2.339398476,-3.199465972,2.434101652,1.396393503,-11.94856035,-10.47429941,-10.67109741,-12.26678889,-11.40719805,-14.92341799,-8.32591348,-5.80072921,-1459.8176725259982 -670,670,R59I,-0.045435409,-0.37814077799999996,-2.26922529,-2.365565035,-2.656506313,0.013935291,0.015190273999999998,-0.106061092,-0.078521358,-0.23978724399999998,-0.5164943120000001,-1.944668281,-2.5937822980000003,-1.967765046,-2.7633650239999996,-2.218155885,-3.094856741,1.01928359,-0.083652297,-10.28759677,-10.10684538,-9.050570412,-10.64357145,-9.603315506,-12.03368109,-8.113570381,-5.564838883999999,-1457.3980478993617 -671,671,R59H,-0.090263181,0.027011045,0.028195907000000003,0.022095261,-0.328139955,-0.003005839,-0.08196505700000001,-0.098561305,-0.039351316000000004,0.10062112,-0.04659903,0.042703646,0.013688167,0.08930238,-0.045111859000000004,-0.248847958,-0.40743195200000004,1.097282766,1.830180642,-3.829263004,-3.41548143,-4.5174290919999995,-4.639884819,-3.2402657930000003,-3.3332538830000003,-4.469526615,-2.18938999,-1454.2213330683298 -672,672,R59K,-0.03219834,0.028808057,-0.0007198080000000001,0.013379948000000001,-0.386167521,0.044967387000000004,-0.040613244,-0.023783435,-0.028311875,0.06301945,-0.005403336,0.009656943000000001,-0.011096558999999999,0.081187001,-0.054427105999999996,-0.19898022899999998,-0.573354812,1.360713075,2.097047964,-4.541923332,-4.230873222,-5.203248756,-5.256186478,-3.178509247,-4.840798958,-4.122695745,-3.4344966360000004,-1460.259461587295 -673,673,R59M,-0.071399525,0.012237583,0.022352959,-1.47320788,-2.432379025,0.009369572,-0.054696873,-0.08810217699999999,-0.108116188,0.041169225,-0.016694059,0.048996508,-0.00429059,-1.136915104,-1.809500655,-2.4015463830000003,-2.463211667,0.841818673,0.751361793,-9.642452947999999,-9.49129718,-8.509604942000001,-10.53417606,-9.157949477999999,-10.51923708,-7.729045212000001,-5.192755711,-1460.517247512471 -674,674,R59L,-0.09395732300000001,0.006592326,-0.192024289,-1.6761025090000001,-2.4079076280000002,0.031967654,-0.062492400999999996,-0.12542224400000002,-0.02004301,0.022748811,-0.00956416,-0.17076143100000002,-0.21328714699999998,-1.3554799480000002,-1.99672507,-2.2975415530000003,-2.518273703,0.945328032,0.7418052890000001,-8.117409747,-8.131699005,-6.509463226,-8.877495003,-7.523837547,-9.544553955,-6.735077498,-3.156569152,-1460.4521245565265 -675,675,R59N,-0.056316372999999996,-0.038195076,-0.059163611,0.014539776,-0.080553187,-0.136352127,-0.10283390699999999,-0.009798838,0.047171195,0.024503367,-0.100893518,-0.013119338000000001,-0.105207884,0.077382708,-0.048303157,-0.035332573,-0.12577380000000002,1.32522348,2.628793189,-3.864551964,-3.103199608,-4.401668861,-4.962664589,-3.575161964,-3.2800647960000004,-4.054445912,-0.211320111,-1464.119411051739 -676,676,R59Q,-0.047080892,0.023520317000000002,-0.039072019,-0.020442319,-1.436483915,-0.00298896,-0.040496735,-0.053665048,-0.051685895999999995,0.081803611,-0.034762978,0.025393113999999998,-0.103537152,0.068204406,-0.10908904400000001,-1.519645695,-1.3533221340000001,0.49850068299999994,1.308308003,-4.071791742,-3.662816978,-4.064066841,-5.050715446,-3.630952034,-3.95040741,-4.851268627,-2.4783538309999997,-1461.6160902781412 -677,677,R59P,-0.061596319000000004,-1.3951278059999999,-1.9419356540000001,-2.091503064,-2.681074897,0.041340867999999996,-0.009504704000000001,-0.113687933,-0.045990764,-1.4736339980000002,-1.316621614,-1.827511065,-2.056360242,-1.850607829,-2.332398299,-2.2880853119999998,-3.074064481,4.010222422,1.7477097519999998,-11.27909548,-11.28242883,-10.96008427,-11.27062286,-10.4635381,-12.41880336,-9.645061972,-7.829719483,-1453.9552707779221 -678,678,R59S,-0.054163725999999995,0.045891017,0.00872414,-0.861572468,-1.875296865,0.055914519,0.005905606999999999,-0.11423305800000001,0.0011172810000000001,0.062126962,0.029655072,0.011229832,0.006218446999999999,-0.427616499,-1.295528437,-1.67945258,-2.0711411490000002,1.6830140040000001,1.4625626090000001,-7.7802523710000004,-6.933135742,-7.733169357,-8.083130119,-7.159741951,-8.992084686,-6.585104841000001,-3.62608655,-1454.5039528943598 -679,679,R59T,-0.072327592,0.01533939,-1.003471343,-1.726944719,-2.823482028,0.040687882,-0.035459925,-0.109195259,0.028848927000000003,0.045815144,-0.015136364,-0.73525841,-1.271684275,-1.528819596,-1.925069841,-2.455904046,-3.1910600089999996,2.4461285669999997,1.32204429,-9.443088037,-8.619338348,-9.50073307,-9.583378754,-8.829517807,-10.68247221,-7.722745159,-5.238081264,-1455.9704634356312 -680,680,R59W,-0.085113947,0.040481937,-0.018723159,-1.5814416359999999,-2.399050209,0.025024459,-0.039688396,-0.130539497,-0.018110882,0.047032952999999995,0.03393092,0.021516305,-0.058962623,-1.208518716,-1.954364555,-2.185908284,-2.6121921340000003,0.99703554,0.7489775679999999,-11.38903369,-10.98464271,-10.29495852,-11.90124191,-11.53694681,-12.22737849,-10.12454405,-9.510327637,-1459.1472740177996 -681,681,R59V,-0.069056612,-0.188942887,-1.504193137,-2.21401196,-3.269411588,0.045472478,-0.034711105,-0.103402119,-0.023226306000000002,-0.075407186,-0.30247858699999997,-1.430694301,-1.5776919719999998,-1.816968968,-2.611054951,-2.482333156,-4.05649002,3.066680349,1.51886324,-9.619794949,-9.611879555,-8.808767952,-9.909516258,-9.243965263,-10.52484572,-7.807601627,-5.104722384,-1455.8873191028833 -682,682,R59Y,0.0052673780000000005,0.07103983700000001,0.029843654,-1.2148503309999998,-2.747228401,0.041797537,0.073808992,-0.063274236,-0.085264244,0.135032701,0.007046973000000001,0.03236036,0.027326947999999997,-0.8157865240000001,-1.6139141369999999,-2.344930965,-3.1495258369999997,1.778872614,1.2822968240000001,-10.03936373,-8.617595482,-10.6292198,-10.61092747,-9.522049583,-10.81702634,-7.641100389,-4.221834521,-1452.143632907886 -683,683,P60A,-0.04836535,-0.004979135,-0.000603067,0.007613094,-0.0036904209999999997,0.041708014,-0.065009165,-0.031721533999999996,-0.017038232,0.011214907,-0.021173176000000002,0.010812166000000002,-0.012018299999999999,0.035312657000000004,-0.020086469,0.071862168,-0.07924301,1.030512501,2.682596954,1.7897401730000002,1.369526855,2.176213158,1.716294601,1.709180725,1.9774855269999998,-1.009612059,1.637411201,-1455.999302429147 -684,684,P60C,-0.034201341,0.038522013,0.0033332690000000002,0.0216651,-1.87440672,-0.00835588,-0.044536717999999996,-0.023865962999999997,-0.037053368999999996,0.011214907,0.065829119,-0.008395946999999999,0.015062485,0.070314606,-0.026984406000000002,-1.344410815,-2.4044026240000003,0.569084163,1.321609415,-4.29919409,-4.156973853999999,-4.128149956000001,-3.885563873,-4.888862717,-4.436420052,-5.30835441,-3.504702734,-1451.3770611151122 -685,685,P60E,0.015935289,0.039689396,-0.034909809,0.012443623999999999,0.019215496999999998,0.036139465,-0.016134585,0.048005163,-0.042570246,-0.01863624,0.09801503199999999,-0.08859954699999999,0.018779929,-0.055802678,0.080689926,-0.023370067999999997,0.061801062000000004,1.4671573,2.665763981,-0.27182323199999997,-0.21159453600000003,-0.165288101,-0.846256012,-0.613860611,0.477883102,-2.000330576,0.38758817100000004,-1460.1382529707626 -686,686,P60D,-0.014733166,0.021542427000000003,0.031799341,0.029683141,0.010643743,0.003779805,-0.041429846,0.011963514,0.005622136,-0.009202998,0.052287850999999996,0.058786125,0.004812557,0.037711286000000004,0.021654995,0.07983167,-0.058544185,1.126870742,2.84560063,-2.587293001,-3.1004631810000003,-3.72216806,-1.98108992,-2.378792389,-1.753951454,-2.795441515,-0.616524957,-1455.862715200521 -687,687,P60G,0.030995073999999997,0.013120405,-0.019277883,0.007261521,-0.021573991,0.006501684000000001,0.023868785,0.038121363,-0.012809228,-0.030938237,0.057179047000000004,-0.027083508,-0.011472257,0.01345049,0.001072552,0.026024807,-0.069172788,1.200850847,2.7073447880000003,-0.143434258,0.203509369,0.310370193,0.10096694199999999,-1.129022812,-0.20299498,-1.662660878,1.159768042,-1454.2223021262325 -688,688,P60F,0.001822431,0.060632872000000004,0.007436027,0.037889361,-1.310573596,0.039709044,0.038301003,-0.034656141,-0.014069165,0.058447822,0.062817922,-0.019478157,0.03435021,0.118753159,-0.042974437000000004,-0.779224275,-1.841922916,0.571954305,1.3606633680000002,-5.310452931,-5.626729156000001,-5.701757072,-4.841486572,-5.538373901,-4.843917953,-6.062264824,-4.8686156689999995,-1454.9135353337042 -689,689,P60I,-0.031402446,0.099016312,0.040388106,0.054243485999999994,-0.070069557,0.033991912,-0.056106086,-0.006698806,0.035502249,0.125177294,0.07285533,0.100981679,-0.020205467,0.137706597,-0.029219625,-0.001932919,-0.138206195,1.239676548,2.841142242,-3.382186952,-3.913380425,-3.049807556,-3.53350573,-3.864397743,-2.5498433080000003,-3.980877027,-2.7821310489999997,-1454.872244677972 -690,690,P60H,-0.016951481,0.018089997,-0.041510258,0.015211658000000001,-0.000633666,-0.011591336,-0.041118969,0.007216006999999999,0.031508895,0.042277665,-0.006097671,-0.040020199,-0.043000316,0.014797278,0.015626038000000002,0.054070314,-0.055337645,1.057823004,2.69928244,-3.6799621,-3.299964127,-4.751987274,-2.550566704,-3.643813324,-4.153479073,-4.607733465,-2.595425396,-1453.3003214355558 -691,691,P60K,-0.006089837,0.016451137,0.018501808999999998,0.008513421,-0.067379763,0.002635555,-0.009142359000000001,-0.003037314,-0.05100500400000001,0.000284639,0.032617634,0.002524404,0.034479214,-0.019979259,0.037006101,-0.053019656,-0.08173987,1.285926774,2.394443934,-2.9933146610000003,-2.206793167,-4.139293747,-2.646391197,-2.745931343,-3.228163849,-3.961418155,-2.587132114,-1451.9839756237343 -692,692,P60M,-0.003974583,0.01357206,-0.002607613,0.009209514,0.028805142000000002,0.033636914,0.014758188,-0.022707353,0.020097745,0.039704421000000004,-0.012560301999999999,0.014417436,-0.019632661000000003,0.035982585,-0.017563557,0.058320891,-0.000710608,1.190057792,2.955570893,-2.478572084,-2.9121144560000003,-2.260661957,-2.873435738,-2.8518336410000003,-1.494814629,-3.199615463,-2.7724602000000003,-1454.6989824254997 -693,693,P60L,-0.056402031,0.025734487,0.012765024,0.0322581,-0.201132372,0.048973072,-0.052737809000000004,-0.060066252,-0.010035957,0.035622489,0.015846485,0.041874241,-0.016344193,0.061359763,0.003156436,-0.11916473300000001,-0.28310001,1.7177603769999998,2.670996696,-2.1670432330000002,-3.16683934,-1.87036837,-2.27328727,-2.706175064,-0.81854612,-2.554108236,-1.914438436,-1454.0800315430388 -694,694,P60N,-0.011285648999999998,0.072278646,0.007683625,0.038777988,-0.28354777600000003,0.091404771,0.020589591,-0.043160888,0.030951296,0.057381206,0.087176085,0.031959659,-0.016592409,0.031261979,0.046293996,-0.196629518,-0.370466033,1.25985554,1.996258778,-3.74771433,-3.5604195560000003,-5.002845993,-3.172810699,-3.1273969189999997,-3.87509848,-5.0994843119999995,-0.862201855,-1449.4905566629022 -695,695,P60Q,-0.008239493,0.033192221,-0.057621955,0.010573048,0.01093068,0.007899241999999999,-0.05663390099999999,0.040154916,-0.01544058,0.057152512,0.009231929,-0.08041295,-0.03483096,0.063178912,-0.042032815999999994,0.055105582,-0.033244222999999996,1.171090344,2.9423430969999997,-0.941399001,-0.594023674,-1.73176886,-0.8709704970000001,-1.6323050540000001,0.122073082,-2.177287562,-0.994877648,-1455.9136663544923 -696,696,P60S,-0.009322236999999999,0.043124534000000006,-0.001805577,0.034161437,0.030974114,0.013435455,-0.015123231000000001,-0.003521242,0.004597453,0.036610737000000004,0.049638330999999994,0.005077444,-0.008688597,0.027970655,0.040352219,0.061101339000000005,0.0008468880000000001,1.110969013,2.691206778,0.5875362120000001,0.36953370700000004,0.097412651,1.482212204,0.19282962,0.7956928790000001,-0.794452721,-0.24295268,-1456.644266935531 -697,697,P60R,-0.004414994,0.043772202,0.019712723999999997,0.040300622,-0.032174445,0.045328600999999996,-0.014805849,0.005975861,-0.005643515,0.06111149,0.026432913,0.027684787000000002,0.01174066,0.067820087,0.012781157,0.004652069,-0.069000959,1.143965006,2.71127695,-2.827401413,-2.994508087,-3.1421442410000004,-1.9882882769999999,-2.88616021,-3.12590625,-4.152948941,-2.761088304,-1449.3192528961226 -698,698,P60T,0.000818803,0.022614209,-0.009437638,0.02905448,-0.035869273,0.018944151,-0.015293381000000002,0.016930986000000002,0.004355085,0.011060752,0.034167666,-0.032543914,0.013668639,0.024179832000000002,0.033929127,-0.037107722999999995,-0.034630822,1.3748626480000001,2.5870370609999997,-2.3142956619999997,-2.8288690869999997,-2.322224701,-1.680622963,-3.088640419,-1.65112114,-3.883220073,-2.715107843,-1458.2447177162394 -699,699,P60W,-0.059501254,0.015172076000000001,-0.030994183999999998,0.03910482,-1.297597785,0.036699766,-0.040822016,-0.07818049099999999,-0.032926462999999996,0.004245137,0.026099014,-0.006697164,-0.055291203,0.059817551,0.018392088,-1.043970493,-1.551225076,0.726531226,1.3549708319999998,-5.519948232000001,-5.533830574,-5.699464057999999,-4.882254105,-5.815959023,-5.668233398,-5.995415764,-4.868615731,-1451.8420352065004 -700,700,P60V,-0.046430782999999996,0.017781198999999998,-0.030849562,0.001336067,-0.08649214,0.067162908,-0.029458435,-0.063403131,0.0043034779999999995,0.068992335,-0.033429937,-0.037817517,-0.023881607000000003,0.014797278,-0.012125145,-0.061187929,-0.111796351,1.3562165330000002,2.503366217,-2.354817043,-3.09641169,-2.29846093,-2.43045639,-2.203055725,-1.745700478,-3.2488386960000004,-1.97232178,-1455.665724887047 -701,701,P60Y,-0.06306302700000001,-0.001563967,-0.017699366,-0.003928153,-0.8071938129999999,0.0076700169999999995,-0.078637273,-0.047488780999999994,0.036197531,-0.035695104,0.032567171,2.56e-05,-0.035424332,-0.0033362870000000003,-0.004520019,-0.5502463160000001,-1.064141309,0.896020182,1.48144071,-6.4184263989999994,-5.974140945,-7.307632401,-5.634822571,-6.374250725,-6.801285355,-6.515645319,-5.522262105,-1453.119049902074 -702,702,E61A,0.063557894,-0.018393502,0.018657924,0.037613292,-0.012261803,0.08635234900000001,0.044354946,0.082760841,0.0042783940000000005,-0.071001751,0.034214747000000004,0.000537546,0.036778302,0.001721021,0.073505563,-0.05330610400000001,0.028782499,1.3507893030000002,2.49975486,-2.155384154,-2.025552635,-1.828559715,-1.9452663419999998,-2.570736351,-2.406805725,-2.625736819,-1.130478774,-1455.0929980776273 -703,703,E61C,0.001840954,0.056106345,0.02455509,-0.020366857,-1.223368361,0.0943779,0.003284038,0.00039787,-0.009460814,0.055272389000000005,0.0569403,0.076871164,-0.027760984,-0.026528789,-0.014204925,-0.711768721,-1.734968,0.82049415,1.421275426,-5.447578735,-4.947538849,-5.048990402,-5.853816642999999,-5.672109261,-5.715438522,-6.429881345,-4.394549692,-1460.935483114794 -704,704,E61D,0.024411174,-0.022018895,0.016038806,0.01835173,0.017772369,0.040897143,-0.024871083999999998,0.073693432,-0.008597704,-0.009966595,-0.034071194,0.044393927,-0.012316315,-0.00871353,0.045416989000000005,0.007855136,0.027689601,1.1983062279999999,2.6400548880000003,1.6444491680000002,2.5599435269999997,1.586135246,1.9702316359999998,0.612622925,1.493312508,0.778377199,1.885214551,-1466.9218147979118 -705,705,E61G,-0.013910738,-0.048552622000000004,-0.039335574,-0.005067915,0.008092791,0.079627469,-0.020897202,-0.006924273000000001,-0.047917821,-0.039719612,-0.057385631,-0.025087297,-0.053583850999999995,-0.015957771000000003,0.005821941,-0.010719298,0.02690488,1.291626607,2.628278631,-1.5524512769999999,-1.431258797,-1.409923874,-1.318636498,-1.676094376,-1.926342842,-2.551537615,-0.241011161,-1457.0650114496239 -706,706,E61F,0.084022179,-0.00046674199999999997,-0.003419893,0.093356546,0.036097238999999996,0.00847417,0.072232424,0.095811934,-0.032435712,0.025197822,-0.026131305,0.06877301799999999,-0.07561280299999999,0.057440812,0.12927228,0.008939763,0.063254715,1.149911372,2.605954966,-5.242485426,-3.7952004169999998,-4.90162825,-6.0686110079999995,-5.493646407999999,-5.953341049,-5.650905524,-3.552738117,-1460.7939728712663 -707,707,E61I,0.09931897199999999,-0.018766218,0.025746305,0.03817622,-0.16817094800000001,0.06833893,0.07645502400000001,0.12218292,-7.38e-05,-0.06563237400000001,0.028099938999999997,-0.051762008,0.10325461699999999,-0.00844311,0.08479555,-0.201510918,-0.13483097800000002,1.354111417,2.066307219,-6.0807211489999995,-5.451577277999999,-5.599807236,-6.590404045,-6.123397636,-6.638419548,-6.903640192,-5.039763884,-1460.2190443850122 -708,708,E61H,0.011416504,-0.0074982469999999996,0.032310451000000004,0.034168159,0.018249952,-0.004774258,-0.049567524,0.07240053099999999,0.035408597,-0.014565388,-0.000431105,0.062676679,0.001944223,0.022458297999999998,0.045878019000000006,0.029438053999999998,0.007061849,1.201053283,2.641557674,-1.794834117,-1.553714561,-1.822637749,-1.8451697459999998,-2.016146286,-1.7365022430000001,-3.2183948210000004,-0.83107925,-1463.3275196095929 -709,709,E61K,0.081382181,0.026833051,0.118560038,0.084336492,0.051632487000000005,0.171953313,0.039165221,0.12359914,-0.147276252,-0.024622475,0.078288577,0.09655611300000001,0.140563962,0.013166086,0.155506897,0.010235895,0.093029078,1.283217775,2.834887473,-1.7137483340000002,-1.4659589919999998,-1.551543823,-2.160256767,-1.858978653,-1.532003433,-3.653917828,-1.028792049,-1460.5078858984634 -710,710,E61M,0.054394780999999996,0.033971043,0.056696705,0.078574935,0.04607429,0.06785062900000001,0.014282757,0.094506804,-0.039827427,0.0032028340000000003,0.064739252,0.06420862,0.04918478900000001,0.002073009,0.15507686,-0.012388618,0.10453719800000001,1.1360743309999999,2.469853608,-4.543099944,-4.168432411,-4.044610229,-5.436769531,-4.38429036,-4.681397186,-5.3317085539999995,-3.182739017,-1461.5440767337568 -711,711,E61L,0.022090156,-0.047770883,-0.024585716,0.02011436,-0.043914108,0.011503476,-0.010121701,0.054302012999999996,-0.041403239,-0.054929402,-0.040612363,-0.014842443,-0.034328989,-0.011171658000000001,0.051400378,-0.064323226,-0.02350499,1.270198658,2.429479188,-4.368369296,-4.024441605,-3.8833066560000002,-5.070032166,-4.185668633,-4.678397423,-5.068428063,-2.932747478,-1459.9376082960516 -712,712,E61N,0.029927954,-0.014141241,0.011966718999999999,-0.011644096999999999,-0.016952500000000002,0.05637949,0.018082728,0.041773179,-0.03285874,-0.033313999999999996,0.005031518,0.035436877,-0.011503438999999999,-0.055003027,0.031714834,-0.055784202000000005,0.021879202,1.187372712,2.582314897,-0.082960959,0.444704124,0.044830710999999995,-0.588744865,-0.199732574,-0.11586219,-2.3808324130000003,0.264784808,-1464.4168613376096 -713,713,E61Q,0.073308264,0.08216560099999999,0.050951592000000004,0.04309535,0.030477973,0.026678433999999997,0.005104982,0.141511545,-0.020087996,0.06995767,0.094373531,0.09752501599999999,0.0043781670000000005,-0.000484179,0.08667487900000001,0.07606690099999999,-0.015110955,1.0600670159999999,2.791847385,-1.3659188519999999,-1.696627426,-1.2735308909999998,-1.5178932569999999,-1.17379464,-1.1677480470000001,-2.771733215,-1.062769415,-1463.0154772307724 -714,714,E61P,0.010494823,-0.9750788579999999,-1.892559423,-2.220149339,-2.8231702000000003,0.09721601,0.01114723,0.009842416,-0.030467012,-0.894647218,-1.055510497,-1.9706686690000002,-1.8144501769999999,-2.2099665490000002,-2.230332128,-2.731179734,-2.9151606660000002,1.824619222,-0.024242249,-5.4524351929999995,-4.917523911,-5.032420387,-5.772874954,-5.875061317,-5.664295395,-6.431826537,-4.26893643,-1456.863289540168 -715,715,E61S,0.059884694,-0.02494304,0.010314503000000001,0.035750894,0.012718307,0.07310902400000001,0.027170126,0.09259926199999999,-0.04275198,-0.041325152000000004,-0.008560927,-0.009342175,0.02997118,-0.0026621759999999996,0.074163964,-0.01445115,0.039887764,1.355524107,2.693486272,-1.84757691,-1.656852486,-1.44380172,-2.251457459,-2.1953826519999997,-1.690390236,-3.649193504,-0.722235318,-1458.935392722953 -716,716,E61R,0.012236341000000001,-0.031955027999999996,0.007580619,-0.000541371,-0.029997036,0.09699304,-0.020821655,0.045294336,-0.031057831,-0.036625469,-0.027284586,0.016303468999999998,-0.001142231,-0.027965607000000003,0.026882865,-0.034520376,-0.025473695,1.334904031,2.534968346,-2.389532899,-2.758966515,-2.327954803,-2.481797539,-2.427677086,-1.951268555,-4.654248852,-1.340625529,-1458.4159779869951 -717,717,E61T,0.042707500999999995,-0.040018981,0.03847835,0.016013805,-0.035050369,0.047572163,0.009279288,0.076135713,0.031730237,-0.04655978400000001,-0.033478177000000005,0.048763744000000005,0.028192955,0.006071656,0.025955952999999997,-0.008942462,-0.061158275,1.155729208,2.502711711,-1.965605602,-1.82394857,-1.711977783,-2.292309151,-2.480125191,-1.519667313,-3.488624273,-0.872233789,-1460.7309853001498 -718,718,E61W,0.012509989,-0.093801157,-0.002535813,-0.017620335,-0.017401177,0.034984327999999995,-0.028692844,0.053712820999999994,-0.062628952,-0.084668849,-0.102933465,-0.013049321000000001,0.007977695,-0.015289883,-0.019950786,-0.054834184,0.020031831,1.4110892069999998,2.462063717,-6.967881641,-6.166737312,-6.3129172129999995,-7.617168861000001,-7.6423485410000005,-7.100236275,-7.806903161,-6.904467192,-1461.502772753127 -719,719,E61V,0.032545471,0.016172889,0.058994500000000005,0.044248441,-0.074498357,0.022989292999999997,0.010752814,0.054338128,-0.136064325,-0.014152066999999999,0.046497844,0.053363543,0.064625457,0.0018537229999999998,0.08664315800000001,-0.08880883,-0.060187884000000004,1.264080769,2.326350792,-5.634791203,-5.15283857,-5.264693123,-5.924326217999999,-5.959013023,-5.873085082999999,-6.150970889,-4.707986016,-1460.0433592847548 -720,720,E61Y,0.027267022000000002,0.014843124,-0.027411743,0.044179771,0.021190484,0.043230267,-0.004781514000000001,0.059315558,-0.075663517,-0.015222871,0.044909119000000004,-0.025148255,-0.02967523,0.028056064,0.060303478,0.04400175,-0.001620782,1.1075755059999999,2.761382807,-4.332429865,-2.982725098,-4.339877983,-5.115777168,-4.452688866,-4.771080208,-5.041387493,-2.7347391410000004,-1460.6258592065424 -721,721,E62A,0.057473014,-0.068437308,-0.022054587999999997,-0.058308636,-1.023939685,-0.037792471,0.069092883,0.045853144000000005,-0.157236776,-0.14233916,0.005464545,-0.071693893,0.027584717,-0.130848237,0.014230966000000001,-0.729163351,-1.318716018,1.9943146409999999,2.054932464,-3.999530995,-4.134581055,-4.044426689,-4.383674133,-3.695254097,-3.7397190019999997,-3.4371146130000003,-2.462619106,-1454.2640481395647 -722,722,E62C,0.042274149000000004,-0.12143756900000001,-0.013264833,-0.086399352,-1.82322916,0.028063802000000002,0.12417614699999999,-0.03962785,-0.211192888,-0.19204332600000001,-0.050831812000000004,-0.058664733,0.032135067,-0.05605222,-0.11674648300000001,-1.6400533080000002,-2.006405012,0.8549783390000001,1.321813471,-8.316265564,-8.264859337,-7.479309586,-8.964481827,-7.815267036,-9.057410034,-6.925598376,-5.295657948000001,-1456.43673148565 -723,723,E62D,-0.0074037059999999995,-0.117832134,-0.024481753999999998,-0.052771188,-0.100650825,-0.007976516,0.026175254,-0.040982666,-0.18075276699999998,-0.20057545,-0.035088817,-0.062290609000000004,0.013327101000000001,-0.049543105,-0.05599927,-0.157552444,-0.043749205,1.486383896,2.224128984,-3.1662677410000004,-2.403731842,-2.341426514,-3.362663338,-3.27143309,-4.452083923,-3.358354545,-1.975962715,-1455.761262289714 -724,724,E62G,0.033345852,-0.045591752,0.012688699,-0.028065378999999998,-1.366168672,0.005711112,0.065714434,0.00097727,-0.162906779,-0.101420483,0.010236979,-0.005008394,0.030385792000000002,-0.029115452000000003,-0.027015305,-1.338544487,-1.393792856,0.773145656,1.337382617,-6.219946792999999,-6.2820165789999995,-5.3518001019999994,-6.742992516,-5.54053418,-7.182390587,-5.161135983,-3.732310641,-1451.3146770521998 -725,725,E62F,0.062333305,-0.116990796,-0.082009373,-0.02231879,-1.220230028,-0.013219301000000001,0.08284925,0.041817359,-0.071007853,-0.257102409,0.023120817000000002,-0.16044077699999998,-0.003577968,-0.080991779,0.036354199,-1.26524793,-1.175212126,1.116169412,1.394104454,-9.539380431,-8.887344673,-7.651852402,-11.09285929,-9.257720345,-10.80712544,-6.561811819,-4.66466524,-1456.3170484942384 -726,726,E62I,0.046353487,-0.055628559,-0.056898239,-0.04850649,-1.344574689,0.014523478000000001,0.086647876,0.006059098000000001,-0.17580372800000002,-0.141360965,0.030103847000000003,-0.007114375,-0.10668210199999999,-0.051669558,-0.045343422,-1.4081183069999998,-1.28103107,0.727198626,1.328669588,-7.938311865,-7.532942139,-6.996696227999999,-8.625377517999999,-7.641829132000001,-8.89471431,-6.2786027870000005,-3.8053244889999998,-1450.8111945623532 -727,727,E62H,0.010724481999999999,-0.11928120800000001,-0.019642727,-0.090061275,-0.66028634,-0.014945307,0.039477632,-0.018028668,-0.15884294599999998,-0.14329443,-0.095267985,-0.074136261,0.034850807000000004,-0.10278144300000001,-0.07734110599999999,-0.541009166,-0.779563514,1.340589675,1.697964927,-6.519878671,-6.082076859,-5.366415161,-7.73332782,-6.16233194,-7.2552415770000005,-5.2951670669999995,-3.477391585,-1450.8361596888863 -728,728,E62K,-0.028776684,-0.089657145,-0.057783907999999995,-0.129572348,-1.893940849,0.004829364,-0.017884629,-0.039668739,-0.274654342,-0.15449398,-0.024820309,-0.08460281,-0.030965005,-0.10374907,-0.155395625,-1.7894590540000002,-1.9984226440000001,0.843555078,1.313262086,-5.3598239119999995,-4.739071152,-4.511423386000001,-7.060913612,-4.718440773,-5.769270637999999,-4.580831733999999,-2.116349898,-1447.2722437148914 -729,729,E62M,0.099765744,-0.035625317999999996,0.011909786,-0.032663627,-0.358510262,-0.05332559,0.108766772,0.090764716,-0.202313716,-0.100680206,0.029429571,-0.07809058,0.10191015099999999,-0.015816112,-0.049511140999999995,-0.350933536,-0.36608698799999995,1.447161352,1.93901136,-6.816425671,-6.09575074,-6.2482927020000005,-8.155899848999999,-6.676098251,-6.906086815,-5.314935974,-3.609943238,-1458.0408958587795 -730,730,E62L,-0.006835099,-0.069357455,-0.053868757999999996,-0.062592013,-1.942943043,-0.003179359,0.020497501,-0.034167697999999996,-0.194971851,-0.108602054,-0.030112856,-0.081288762,-0.026448753999999998,-0.04000742,-0.085176605,-1.4758399309999999,-2.410046154,0.94388828,1.343679321,-6.984019052000001,-6.235318877999999,-6.272127257999999,-8.018081383,-6.8501548539999995,-7.544412887999999,-5.0867461689999995,-2.988049167,-1455.765471980907 -731,731,E62N,0.0032209229999999997,-0.072703974,-0.04316417400000001,-0.07238916,-1.491877677,0.0054445909999999995,-0.002186603,0.008628448,-0.095499586,-0.170502767,0.02509482,-0.087471995,0.001143648,-0.056698973,-0.088079346,-1.104165272,-1.8795900819999998,0.624383502,1.340195457,-6.212770065,-5.601658859,-5.467866455,-7.326501541,-5.756139107,-6.911684364,-5.756159806,-3.832298895,-1447.1385021624155 -732,732,E62Q,0.061097446,-0.069194688,-0.007620568,-0.045751279000000006,-0.310831814,-0.087726809,0.050104307,0.072090584,-0.051009757999999995,-0.10445769199999999,-0.033931683,-0.086116235,0.070875099,-0.113353654,0.021851097000000003,-0.33497267,-0.286690958,1.771994887,2.2127113169999997,-2.953250681,-2.28539772,-2.777685242,-4.14643222,-2.495393387,-3.061344833,-2.943035715,-1.970683841,-1455.3849908486009 -733,733,E62P,-0.016243763,-1.479490774,-2.007118191,-2.3435573080000003,-2.7961000169999997,0.002751608,-0.000136789,-0.032350737000000004,-0.219519247,-1.665769511,-1.293212036,-2.1230137940000002,-1.8912225880000002,-2.2670523940000002,-2.420062221,-2.6953968839999995,-2.89680315,0.082204336,-1.116553491,-9.228824875,-9.313409308999999,-8.538037819,-9.673707855,-8.714990112,-9.903979279,-8.069129252,-6.519158986,-1457.8481176863424 -734,734,E62S,0.012566713,-0.039193313,-0.005399597,-0.049149026,-0.991022422,-0.040509579,0.00982489,0.015308536000000001,-0.157198668,-0.067493949,-0.010892677,-0.050283172,0.039483977999999996,-0.060382625,-0.037915427,-0.670589813,-1.31145503,0.894347698,1.448742021,-4.583587503,-4.799233322,-4.467634033,-5.481898811000001,-3.932023071,-4.237148277,-4.777297667,-3.114443917,-1449.1948882332072 -735,735,E62R,0.036320027000000005,-0.043425958,0.000866879,-0.070105213,-2.055450033,0.02293856,0.053948540999999996,0.018691513,-0.155366809,-0.12142668400000001,0.034574769,-0.066141495,0.067875252,-0.052963783,-0.087246642,-1.7066566459999999,-2.404243419,0.918369718,1.323135725,-4.6518779939999995,-3.88831498,-3.779259232,-5.8433144,-4.666684685,-5.0818166730000005,-4.171810855,-1.739471885,-1449.8193881073967 -736,736,E62T,-0.012736448000000001,-0.087258738,-0.087441348,-0.084723466,-0.29157128600000004,-0.060228040999999996,-0.027513164,0.002040268,-0.176732663,-0.11171819,-0.062799286,-0.128939876,-0.04594282,-0.093840781,-0.075606151,-0.26823922,-0.31490335199999997,1.542292374,2.081401642,-4.581104628,-4.593128265,-4.220194962,-5.073418633,-4.212344231,-4.80643705,-5.1275822689999995,-2.045240493,-1451.2979572187178 -737,737,E62W,0.086498837,-0.06090279,-0.038870471000000004,-0.012690395,-1.9314546240000001,-0.075435128,0.091618831,0.08137884299999999,-0.14861068800000002,-0.184164651,0.062359072,-0.12878382300000002,0.051042881,-0.046804825,0.021424036,-1.6645843390000001,-2.198324909,0.6878522159999999,1.31160748,-10.49994027,-9.773269691,-8.897498947,-11.927321300000001,-10.23526061,-11.66635082,-8.574534898,-7.384837031,-1464.0598307619803 -738,738,E62V,-0.001870541,-0.121185084,-0.017289387,-0.043605708,-0.936311053,0.012342856000000001,0.023304282000000003,-0.027045363,-0.18686835,-0.164644898,-0.07772527,-0.06591284900000001,0.031334075,-0.028124287999999997,-0.059087127999999996,-0.6435998479999999,-1.2290222579999999,1.528433409,1.780285502,-6.587497131,-5.939729423999999,-5.596568085,-7.1417764429999995,-6.719195366,-7.540216339,-5.222336449,-2.5934347680000003,-1453.5302119972184 -739,739,E62Y,-0.008455438000000001,-0.070276425,0.046305106,-0.059928347,-1.2178737,-0.003224918,-0.006609425,-0.01030145,-0.160316776,-0.12289499400000001,-0.017657855,-0.001258893,0.09386910400000001,-0.08396715,-0.035889542999999996,-0.965614335,-1.470133064,1.0466992929999999,1.428955096,-9.857638837,-9.821087486,-7.830883881,-11.13826691,-9.066796356000001,-11.43115955,-6.787782095,-4.94285288,-1451.48041043384 -740,740,R63A,-0.053937372000000004,0.02686806,-0.027505855,-0.027537789,-1.552993834,0.02522155,-0.034855687999999996,-0.073019055,-0.05945277,0.024921336000000002,0.028814784,-0.036995679,-0.018016031000000002,-0.011864608,-0.043210969,-1.204657826,-1.901329841,0.783630527,1.347390092,-6.139308664,-5.8964319000000005,-6.442352402,-6.174938599,-6.831125572,-5.351694847,-4.181020258999999,-2.463916723,-1447.6005876334384 -741,741,R63C,0.0037786820000000002,0.052228344,0.039806486,-0.11080175800000001,-1.5772824909999998,0.012800858,0.0063996090000000005,0.001157754,0.061034622000000004,0.009931759,0.09452492900000001,0.048658555,0.030954417,-0.092447451,-0.12915606400000001,-1.581911065,-1.572653916,1.0241111840000001,1.343607555,-8.949303322,-9.903201141,-8.712929184,-8.521634322999999,-9.315056709,-8.293695251,-7.146964873,-5.792937447000001,-1452.177134564612 -742,742,R63E,-0.049669841,0.023391586000000002,-0.042143479000000005,-0.036506677,-1.482423194,0.025941044,-0.019756125,-0.079583556,0.02516146,0.003865467,0.042917705,-0.07774742,-0.006539538,0.00172408,-0.07473743299999999,-1.6450813569999998,-1.319765031,0.7323203859999999,1.316981787,-10.41243823,-12.67499421,-9.299268188,-10.58946328,-10.19460715,-9.303858307,-6.100753338,-2.8634247719999997,-1440.8377178683877 -743,743,R63D,-0.093154388,0.00822422,-0.169084097,-1.836651517,-2.506009658,0.057251345999999995,-0.016668201,-0.169640574,-0.049309202,0.001611686,0.014836753999999999,-0.13328071800000002,-0.204887475,-1.497424246,-2.175878787,-2.2817575469999998,-2.7302617689999997,1.168358658,0.757981958,-11.29103313,-12.77301491,-12.5106276,-11.18095947,-9.7030355,-10.28752816,-7.3795049729999995,-4.374417863,-1445.1811440540478 -744,744,R63G,-0.064787167,0.020064104,-0.015426586,-1.322110985,-2.512185941,0.005717024,-0.034450614,-0.09512372,-0.007465448,0.027696412000000004,0.012431796,-0.03010389,-0.0007492810000000001,-0.834621542,-1.809600427,-2.244839517,-2.7795323639999996,1.83777074,1.33816789,-9.22614644,-9.844372314,-8.594358459,-9.663007393,-9.636149811000001,-8.392844222999999,-6.518095446,-4.513749946,-1449.7383205322549 -745,745,R63F,-0.069008369,0.029277964,-0.08650067199999999,-0.074559971,-1.8281826380000001,-0.061251133,-0.081522341,-0.056494395999999995,0.023797897000000002,-0.032071427,0.090627355,-0.04345605,-0.129545294,0.028628318,-0.177748259,-1.4123506730000002,-2.244014602,0.60156222,1.319371867,-8.530368129,-8.331327965,-8.043347099,-9.508874413,-9.067476822,-7.7008143460000005,-6.754426157999999,-4.699963656,-1439.0967577281408 -746,746,R63I,-0.053876189000000005,-0.001550838,0.045928416,-0.065170486,-1.001374095,0.060208595,0.018931754,-0.126684131,-0.023974885,0.064929465,-0.06803114,0.075752914,0.016103917,0.030027553999999998,-0.160368525,-0.534333003,-1.4684151859999999,0.716476379,1.43715286,-9.291897765,-10.21273226,-9.04242157,-9.14089209,-8.187891953,-9.875550948999999,-6.595232809,-2.50538904,-1445.0718291494995 -747,747,R63H,-0.063345388,-0.009265087,-0.031860967999999996,-0.054240048,-0.532573946,0.037572934,-0.030349152999999997,-0.09634162199999999,0.08146513799999999,0.005718604,-0.024248778,-0.031477879,-0.032244057,-0.035958123,-0.072521973,-0.421945722,-0.6432021689999999,1.4089443990000001,1.867423219,-5.947789211,-7.30736013,-5.5390885160000005,-5.753142616,-5.889709273999999,-5.249645515,-5.07289508,-2.5520022669999998,-1449.7788949362002 -748,748,R63K,-0.060374055999999995,0.035512884,-0.009030466,-0.038527773,-0.162804455,0.056068325999999995,-0.046524829000000004,-0.074223283,-0.032222669,0.046654565999999995,0.024371201000000002,0.013749305,-0.031810236,0.005073814,-0.08212936,-0.146046799,-0.17956211100000002,1.430093859,2.296490931,-7.332225139,-7.598518326000001,-6.723132065,-7.632073029,-7.302365341000001,-7.405036934,-5.874237096,-2.447747845,-1450.253584427759 -749,749,R63M,-0.051347407000000005,0.06806669900000001,-0.007027078000000001,-0.058392767000000005,-1.270809434,0.010663632,-0.057121157,-0.045573656,0.083235085,0.08385190099999999,0.052281496,-0.023821027,0.009766871,-0.008987105,-0.107798429,-1.144038186,-1.3975806819999999,0.688106978,1.341730603,-7.421247154,-8.512249268,-7.6127682420000005,-7.479885887000001,-7.442247237999999,-6.059085136,-6.2742560229999995,-4.082656486,-1445.3259700005874 -750,750,R63L,0.011221663,0.038670758,-0.014093258000000001,-0.010820682,-0.418237842,-0.010758203999999999,0.005697707,0.016745619,0.024830702000000003,0.036347288,0.040994227,-0.022672988999999998,-0.0055135259999999995,0.009836859,-0.031478223,-0.306941532,-0.529534151,1.130292289,1.752828686,-4.497442244,-4.641254288,-4.218142548,-4.890832207,-5.012228592,-3.7247535860000003,-5.243967068,-1.942311951,-1438.2389116766863 -751,751,R63N,-0.080355608,-0.017129643,0.040729468,0.05179803,-1.582375994,-0.07005795,-0.090942465,-0.06976875099999999,0.019867603,0.028224475,-0.06248376,0.049132589000000004,0.032326346,0.120724249,-0.017128189,-1.4123506730000002,-1.752401314,0.448112726,1.31190732,-10.24764977,-11.55348384,-9.331865898,-10.17172666,-10.03741586,-10.14375659,-7.327211148,-4.085044528,-1450.9305766685866 -752,752,R63Q,-0.032623525,0.05981111,-0.050418462000000004,-0.015736444,-0.693159062,0.003327024,-0.025634574,-0.039612476,3.75e-05,0.07184611099999999,0.047776109000000004,0.015289467,-0.11612639,0.008694059,-0.040166946,-0.514601681,-0.871716443,0.8582965109999999,1.484045655,-7.800900121000001,-9.20846595,-7.387675354,-7.315996254,-7.508277206,-7.584085837999999,-5.791352037,-2.788628912,-1447.2621888662688 -753,753,R63P,-0.028605882000000003,0.003872278,-0.016073859,-0.023242573,-1.086821958,-0.0027440340000000002,-0.018305773,-0.03890599,0.002451501,-0.008168219000000001,0.015912773999999998,-0.009977855,-0.022169862999999998,-0.013150964,-0.033334181000000004,-0.806714335,-1.36692958,0.80918625,1.395967489,-6.22511566,-6.010014694,-5.748600685,-6.272649055,-7.102545952000001,-5.9917679139999995,-5.600562557999999,-1.308622927,-1451.2061903756112 -754,754,R63S,-0.06283103799999999,0.010383432,-0.032349657999999996,-0.053699102,-1.2961362029999999,0.021958796000000003,-0.056132727,-0.069529348,0.051454634000000006,0.012871823999999999,0.00789504,-0.041153503,-0.023545812000000003,-0.030677641000000002,-0.07672056299999999,-1.02094819,-1.571324216,0.992518998,1.399458909,-6.4089486529999995,-7.492794677999999,-6.446434525,-6.292117966,-6.166379302999999,-5.6470167920000005,-5.462545058,-2.421000261,-1448.379903475754 -755,755,R63T,0.002459675,0.059841810999999995,0.023692966,0.007443551,-0.626124444,0.000400691,0.019389115,-0.014469766,-0.015746644,0.06916190700000001,0.050521714,0.031447134,0.015938797,0.023284213999999998,-0.008397112,-0.46905748,-0.783191408,0.821384722,1.490724102,-6.676408226,-7.77584819,-6.719531998,-6.392919113,-7.045464691,-5.448277138,-5.122309315,-2.71962727,-1446.7411921699531 -756,756,R63W,-0.07595975099999999,-0.03415708,0.008220798,-1.042068925,-2.318079555,-0.021050898999999998,-0.066800785,-0.085118717,0.097584111,-0.038597643,-0.029716517,-0.001299112,0.017740706999999998,-0.548690149,-1.5354477,-1.9265396680000002,-2.709619441,1.778474736,1.413689428,-9.062352611,-9.407581352000001,-8.898942513,-9.466279839,-9.502400795,-8.036558556000001,-7.738876758,-5.288188634,-1445.993060789071 -757,757,R63V,-0.001262943,0.03592568,0.00911717,-0.023027042,-1.337554196,-0.001112964,0.037181537,-0.039707422,-0.007937356999999999,0.009470619,0.062380740999999996,-0.026630767000000003,0.044865105999999995,-0.028372612000000002,-0.017681471,-1.0914258479999999,-1.583682543,0.818372951,1.3634916380000002,-8.13818463,-8.896631371,-8.290886726,-8.102747215,-7.6903937529999995,-7.710264083999999,-5.672094502999999,-1.936902207,-1447.7950737690553 -758,758,R63Y,-0.035078013,0.073713263,0.022152567,0.013112338000000001,-1.305136837,-0.021424274,-0.040634627,-0.029521397999999997,-0.055383349000000005,0.075605498,0.071821028,0.059356294000000004,-0.01505116,0.10036246900000001,-0.074137794,-0.933605885,-1.6766677890000001,0.46229254399999997,1.334906535,-8.670783517,-10.26926845,-8.456500748,-9.059950462,-8.572810555,-6.995387375,-6.1590945,-4.424966096,-1440.1550757102668 -759,759,F64A,0.013724988999999998,-0.40015947799999996,-1.6165436880000001,-2.089278195,-3.3888094310000003,0.055516183,0.022542617999999997,0.004907359,,-0.365233708,-0.435085248,-1.673063391,-1.560023984,-2.1443715880000003,-2.034184802,-2.801162415,-3.9764564460000003,2.67816244,0.928730073,-10.31397514,-8.348962143,-10.07585074,-11.10702494,-11.24063365,-10.79740421,-6.627142216,-4.86424536,-1446.0248967576772 -760,760,F64C,-0.000465079,-0.101256261,-1.4007833230000002,-2.83977023,-3.4444231860000003,0.06528308299999999,0.049790482000000004,-0.050720639000000005,,-0.053183325,-0.149329197,-1.288717434,-1.5128492119999999,-2.189924656,-3.489615803,-3.1197167560000003,-3.7691296160000003,0.910740673,0.099954217,-12.32212331,-10.94997182,-12.81034616,-11.37790232,-12.93668108,-13.53571516,-7.773932814,-6.185260378,-1446.1760642752051 -761,761,F64E,-0.037619673,-1.145113425,-1.972874924,-2.068206371,-3.02234433,0.04696629,0.030016941000000002,-0.10525628599999999,,-1.107199067,-1.183027783,-2.04893611,-1.8968137369999998,-2.132064134,-2.004348608,-2.663916225,-3.380772434,3.45357677,1.13492915,-12.76323986,-10.74397124,-12.83867902,-12.399367999999999,-13.66450612,-14.16967491,-7.655104422999999,-6.177034591,-1455.2919944329187 -762,762,F64D,-0.033295451000000004,-1.9588083569999999,-2.1398885780000003,-2.258098772,-3.075736094,0.030130052999999997,0.018020975,-0.08461187699999999,,-2.012386466,-1.905230248,-1.9998809990000002,-2.279896157,-2.42979651,-2.086401033,-2.484527346,-3.666944842,2.515367619,-1.59410191,-15.8982201,-13.49726414,-17.40789885,-15.25777419,-17.42876489,-15.89939844,-9.940877565,-10.09132959,-1459.9230077941902 -763,763,F64G,-0.000137964,-1.6692987780000001,-2.055692976,-2.209684094,-3.0805490819999997,0.035771395,0.036574186,-0.036850113999999996,,-1.8067700869999999,-1.531827469,-2.209237968,-1.902147983,-2.116274734,-2.3030934530000002,-2.7730655619999998,-3.3880326010000004,2.0234054930000003,-1.628992269,-14.67804395,-13.71830597,-14.89361069,-14.26991566,-15.71274969,-14.79563773,-9.940877565,-10.09132959,-1447.7663215715438 -764,764,F64I,-0.009748666999999999,0.023435532999999998,-1.122824316,-1.8018144319999998,-2.809557375,0.003588868,0.052482182,-0.071979516,,0.011708257,0.035162808,-0.7434720920000001,-1.50217654,-1.87581814,-1.7278107230000002,-2.80561024,-2.81350451,1.961784681,0.865883733,-8.656968736,-8.257107513,-5.8757360610000005,-8.394733559,-10.53141696,-10.22584959,-5.507094298999999,-3.639622919,-1441.7811560868286 -765,765,F64H,-0.031702786000000004,-0.37144605399999997,-1.855072162,-2.214719148,-2.635383711,0.005981868,0.034147934,-0.097553506,,-0.281027276,-0.461864832,-1.74724859,-1.9628957340000002,-2.034496598,-2.3949416969999997,-2.487167442,-2.783599979,1.267511246,0.028652333,-12.27170628,-14.91300625,-11.72822225,-8.655014816,-12.59842937,-13.46385873,-6.865003678,-4.1980405869999995,-1441.0262856893241 -766,766,F64K,-0.015607968,-0.894579352,-2.123853041,-2.5826838530000003,-3.226927432,0.029842726,0.055787385999999994,-0.087003322,,-1.0088943129999999,-0.78026439,-1.919373662,-2.328332419,-2.553409156,-2.61195855,-2.784231251,-3.669623613,2.422120165,0.290970434,-14.11163622,-12.77386147,-14.10982631,-12.38772823,-15.50184618,-15.78491892,-7.499532143,-5.439412143999999,-1453.9248338146135 -767,767,F64M,-0.036484905,0.023722338,-0.01221472,-0.098431851,-1.78343415,-0.026789322999999997,0.001281141,-0.074250951,,0.022417964,0.025026711,0.036704546,-0.061133985,-0.065886885,-0.130976816,-1.572683087,-1.9941852130000002,0.879802373,1.329783233,-8.14933502,-7.332246315,-6.118420456,-7.981533592000001,-9.393772903,-9.920701836000001,-5.80238681,-2.78262693,-1456.2143568508327 -768,768,F64L,-0.005539031,0.01245872,-0.9043608759999999,-1.830372352,-2.346558986,0.024664339,0.048682277999999995,-0.059760339,,-0.020268098000000002,0.045185538,-0.6665269220000001,-1.14219483,-1.7468071040000002,-1.913937599,-2.8101381119999997,-1.88297986,2.065758208,0.972251407,-7.5938712420000005,-6.963559631,-5.634145072999999,-7.054276176,-9.176542076,-9.140833252,-5.829044635,-2.5966034330000003,-1444.9080333700404 -769,769,F64N,-0.039346988,-1.277772915,-2.5653905480000003,-1.9020828,-3.191343685,0.018422714,-0.004995681,-0.073698294,,-1.146264604,-1.409281225,-1.9788571769999999,-3.1519239189999997,-2.135771416,-1.668394184,-2.843714766,-3.5389726039999996,3.421659296,1.096727314,-16.03152285,-14.51413927,-17.83179681,-13.34323047,-16.68772018,-17.7807275,-9.779764857,-9.352302711,-1457.3894480410963 -770,770,F64Q,-0.052006576,0.021362062999999997,-1.062696415,-1.857375187,-2.642892061,0.057610204000000005,-0.00378812,-0.10022503199999999,,0.01913441,0.023589716,-0.919373662,-1.206019167,-1.729500415,-1.985249958,-2.659292514,-2.6264916069999997,2.3711038980000003,1.132025689,-13.54362713,-11.03091702,-13.70962211,-13.08228495,-14.42407352,-15.47123804,-6.738277985,-3.936784335,-1457.0190613674931 -771,771,F64P,-0.0023103520000000003,-1.691576636,-2.1925566119999997,-2.3301431,-2.7358260519999997,0.027564906,0.032702596,-0.037323300000000004,,-1.8148368730000002,-1.568316399,-2.2283001380000003,-2.156813086,-2.21451815,-2.44576805,-2.746370241,-2.725281863,2.4151761780000003,-1.31048882,-13.85739738,-13.125532999999999,-14.51842745,-13.34957873,-14.819194400000002,-13.47425335,-7.245096751,-5.700397604,-1458.4784874999896 -772,772,F64S,0.005165746,-0.9254701759999999,-2.007173027,-2.422540943,-3.494443125,0.015783174,0.035549408,-0.025217916,,-0.881916945,-0.9690234059999999,-2.206416694,-1.80792936,-2.580814877,-2.264267009,-3.5106069769999997,-3.478279273,1.181513072,-0.444501162,-10.7208713,-10.399001400000001,-10.78474109,-9.711034172,-11.89410161,-10.81547824,-6.903568446,-5.701543528999999,-1448.842638307251 -773,773,F64R,-0.01974513,-1.18384842,-2.144861517,-2.3533201790000002,-3.301163574,0.050730748,0.021924507000000003,-0.061414765999999996,,-1.159270454,-1.208426386,-2.352819469,-1.936903565,-2.300474086,-2.4061662719999997,-2.983593852,-3.6187332960000003,1.271028951,-0.5893832179999999,-13.59526792,-12.70852303,-10.41536175,-11.78033474,-15.43554123,-17.63657888,-6.550318602000001,-4.774481488,-1446.7615892789327 -774,774,F64T,0.011485381000000001,-0.202048388,-1.515333579,-2.330658398,-2.630296893,0.012677202,0.035352269,-0.012381507,,-0.10921483300000001,-0.294881942,-1.4316654819999999,-1.599001675,-2.190639713,-2.470677082,-2.530606277,-2.729987509,0.9607310579999999,0.075865773,-10.34940045,-9.705437851000001,-9.03081749,-10.628728500000001,-10.81334212,-11.5686763,-6.517542119,-4.917899263,-1444.067528272979 -775,775,F64W,-0.020653294,-0.003878135,-0.110487266,-1.561012024,-2.549393345,0.014975277,0.010346714,-0.051653302000000005,,-0.028651729,0.02089546,-0.11936574900000001,-0.10160878300000001,-1.345709513,-1.7763145340000002,-2.554255214,-2.544531475,0.9637642809999999,0.745863883,-11.08181953,-11.11045232,-11.88724066,-8.486794876,-12.13695214,-11.78765763,-6.091807964,-3.308432387,-1453.1133143105544 -776,776,F64V,0.009114989,-0.007850148000000001,-0.00848575,-1.193081601,-2.270670191,0.0014335139999999999,0.045147071,-0.026917093,,-0.036288634,0.020588339,-0.012297396,-0.004674103,-0.637968115,-1.748195086,-2.223596872,-2.31774351,1.7198634240000001,1.332249403,-7.797226328,-6.115346474,-6.138590279,-8.068065239,-9.556761116,-9.10736853,-5.398436101000001,-2.06766327,-1447.828997997567 -777,777,F64Y,-0.012969563,0.015158217,0.006973345,0.027411037000000003,-1.611485958,-0.023906392000000002,0.011080446,-0.037019572,,0.011277452,0.019038982,0.03856884,-0.02462215,0.036435402,0.018386671,-1.6026266580000001,-1.6203452580000002,0.630179217,1.31220221,-7.542598911,-8.01515918,-9.12860836,-5.57043898,-8.447370796,-6.551417236,-4.2237465,-2.286461081,-1446.6311262981035 -778,778,P65A,-0.014314967,0.011552608,0.006077418,0.009572938000000001,-1.414854298,0.036509902000000004,0.009387425,-0.038017358,-0.026162439,0.022363176000000002,0.0007420389999999999,0.012563841000000001,-0.000409005,0.011216921999999999,0.007928953,-1.3937796390000001,-1.4359289569999998,0.9269574290000001,1.34849867,-5.368892606,-5.7930937810000005,-5.586125312999999,-4.344099937,-6.4752117920000005,-4.645932205,-5.053259387,-0.958658655,-1445.6897768997587 -779,779,P65C,-0.024244545,0.029899921,-0.104559116,-1.512368547,-3.03405659,0.140301902,0.003760695,-0.052249785,-0.04895053,0.042251142,0.0175487,-0.076336087,-0.132782145,-1.40714071,-1.6175963830000002,-2.5427104590000003,-3.5254027210000003,0.838573874,0.723701128,-12.71509686,-11.83436613,-12.50607805,-14.04272374,-14.33311012,-10.85920627,-8.46723573,-4.670034299,-1443.722596234642 -780,780,P65E,-0.076936322,0.007836665999999999,-1.08778714,-2.056855574,-3.178608368,-0.011789808,-0.081631614,-0.07224103,0.011787229,-0.009925891,0.025599222999999997,-0.673991837,-1.5015824430000002,-1.962831959,-2.150879189,-2.797371712,-3.5598450230000003,1.8629310769999998,0.8037116940000001,-13.69747834,-12.409296300000001,-15.51843599,-13.97775693,-16.37844583,-10.20345666,-8.786477949,-4.075681959,-1434.1094075432047 -781,781,P65D,-0.007828136,-0.512012328,-1.829379806,-1.9509769819999998,-3.0157580989999997,0.036723431,0.019961494,-0.035617765,-0.00619855,-0.362839721,-0.661184934,-1.681390973,-1.9773686380000002,-2.131382003,-1.77057196,-2.664891761,-3.366624437,2.7094122389999997,0.9624097659999999,-14.18483879,-12.55095097,-15.25666372,-15.58529152,-15.53070547,-12.00058225,-9.169106934,-5.394382587999999,-1433.2552567687817 -782,782,P65G,-0.021974702999999998,-0.003964627,-0.03512254,-1.671626394,-2.824370872,0.050792686,0.0016784220000000002,-0.045627827,-0.020297183,-0.013286335,0.005357081,-0.06292307,-0.007322009,-1.371077783,-1.9721750040000001,-2.501684112,-3.1470576319999997,0.7038904509999999,0.714856285,-11.1458355,-10.25039447,-11.65426146,-9.963110054,-15.38340816,-8.478003357,-6.856502364,-3.243425637,-1444.3846558546647 -783,783,P65F,-0.07672585900000001,-0.022937487000000003,-0.380402994,-1.871867945,-2.646213716,0.073839195,-0.00810489,-0.145346828,-0.20623270300000002,0.032546507999999995,-0.078421482,-0.223213913,-0.537592074,-1.305228159,-2.43850773,-2.382805961,-2.9096214710000003,1.516513564,0.8844115309999999,-13.64491739,-13.57938696,-12.04161774,-17.99358546,-14.26436367,-10.34563309,-8.327905156,-4.784129655,-1436.393065690063 -784,784,P65I,-0.046100929000000006,0.018896786999999998,0.022447619,-2.0884452209999997,-2.414665711,0.014761453999999999,-0.040483537,-0.051718321,-0.11927706099999999,0.042284460999999995,-0.004490888,0.047029071,-0.002133834,-1.6256784309999999,-2.551212011,-1.98309693,-2.846234492,0.590865189,0.687786309,-11.3728154,-10.304407199999998,-11.08411542,-11.46849491,-15.36621362,-8.640845848,-7.781307439,-3.802290053,-1457.5352273550816 -785,785,P65H,-0.036473154,0.016670462,-0.016075728,-0.96000361,-2.1949884219999998,0.064508101,-0.004853212,-0.068093095,-0.04557594400000001,0.017317285,0.016023638,-0.031141496,-0.00100996,-0.711383366,-1.208623853,-2.1002103290000003,-2.289766515,1.868632593,1.399528087,-12.07621915,-11.18357777,-10.87283597,-15.87225877,-12.19385343,-10.25856979,-7.679228847999999,-2.672501875,-1432.2211785460822 -786,786,P65K,0.011009463,0.030209235,0.06250006400000001,-1.62078334,-2.53504946,-0.009152216999999999,0.056867235,-0.034848309,-0.06884535900000001,-0.048973345,0.109391814,0.034664567,0.090335561,-1.139602333,-2.101964347,-2.451263342,-2.618835578,0.701273183,0.7332867470000001,-13.45046829,-12.50085229,-13.93208151,-13.78073704,-15.97346814,-11.06520245,-7.992176742000001,-4.097087225,-1445.4978061625734 -787,787,P65M,0.09840180400000001,0.015083721999999999,-1.290873375,-2.264831718,-2.5910522080000002,0.014229945,0.128848916,0.067954691,-0.008126608,0.020146575,0.010020868,-0.9664055640000001,-1.615341186,-2.2972101869999997,-2.232453248,-2.052568694,-3.1295357210000003,1.816676486,0.48103319299999997,-9.332142043,-8.559300056,-10.01375991,-9.64707238,-12.57203146,-5.86854641,-6.756379475,-4.285118399,-1441.2656716140918 -788,788,P65L,-0.014751306,0.014214879,-0.33796622299999995,-1.693614309,-2.303535144,0.017136393,0.021866475,-0.051369085999999994,-0.030692436,-0.010153245,0.038583002000000005,-0.23832504899999998,-0.437607397,-1.5393996269999999,-1.8478289909999999,-2.274554748,-2.33251554,1.360870581,0.7853427009999999,-7.821619812000001,-7.305230057,-7.285926399,-7.921430946,-12.9168375,-3.678674156,-4.940324523,-2.7304528660000003,-1446.749927955214 -789,789,P65N,-0.013402401000000001,-0.027247977000000003,0.058529588,-1.1080201440000002,-2.4645895540000002,0.000522434,-0.006257991,-0.02054681,-0.14542164,0.0059861969999999995,-0.06048215,0.074214093,0.042845083,-0.687530799,-1.5285094890000002,-2.044949297,-2.8842298110000004,1.856859485,1.412617518,-13.44981071,-12.46526845,-12.7715477,-15.56986079,-15.57950259,-10.86287403,-8.352456782,-4.6459719569999995,-1438.1305708992295 -790,790,P65Q,-0.083736248,-0.053953462,-0.19780773100000001,-1.6085037080000002,-2.323799824,0.108071203,-0.043994341,-0.123478154,-0.031140972000000003,-0.050201259000000005,-0.057705664000000004,-0.15015709300000002,-0.245458368,-1.673866474,-1.543140942,-2.332314969,-2.315284679,1.220030172,0.7381123209999999,-11.99934235,-12.17420722,-13.28824072,-12.35583136,-13.39352733,-8.784905098,-7.75039976,-3.203717795,-1442.2381217302755 -791,791,P65S,-0.024183394,-0.003306002,0.012245588,-0.178302774,-1.91444365,0.050568825,-0.010254133,-0.038112653999999996,-0.026142497,-0.009603834,0.002991831,0.012184644,0.012306532,-0.12118336800000001,-0.23542217899999998,-1.5494639780000001,-2.279423321,1.0572590640000001,1.349105188,-10.54720749,-10.15560621,-9.197173599,-11.31379551,-12.92093925,-9.148522903,-7.127304313,-2.671539149,-1435.5617774212733 -792,792,P65R,-0.002576072,-0.029280011,-1.41606579,-2.1249131759999997,-2.9158431289999998,0.060691512,0.028468487,-0.033620631,-0.078902444,-0.031363245,-0.027196777000000002,-1.3382761890000001,-1.4938553909999999,-2.040691882,-2.20913447,-3.02649931,-2.8051869480000002,2.385289069,0.9011420509999999,-11.07453513,-11.38429401,-10.62846519,-11.67589157,-13.25863512,-8.425389771,-7.584570327000001,-3.0968600669999997,-1431.8974623791873 -793,793,P65T,-0.072020972,-0.015292307,-0.011117082,-1.5643125969999998,-2.386225246,0.034033302,-0.047858254,-0.09618369,-0.011559783999999998,-0.01414397,-0.016440643,0.021652362,-0.043886525999999995,-1.265430107,-1.8631950869999998,-2.241847019,-2.530603473,0.828908773,0.7360786909999999,-10.03961451,-9.303601517,-10.05400492,-10.78871479,-11.48953835,-8.562212959,-7.317749571,-3.0939946369999998,-1434.1344895241782 -794,794,P65W,-0.015388326,-0.284308487,-1.689654983,-2.598446441,-3.339318818,0.034518468,0.007471455,-0.038248106000000004,-0.042449308,-0.17504486600000002,-0.393572108,-1.712091225,-1.667218741,-2.7641422469999997,-2.432750635,-2.9966220089999998,-3.6820156269999997,0.9154709940000001,0.003368363,-15.29183539,-13.81318473,-16.33257647,-17.13588286,-17.25705077,-11.92048213,-9.924382312,-6.361046556,-1445.7336955107749 -795,795,P65V,-0.005848987,0.058583367000000004,0.06395485599999999,-0.9910799309999999,-2.5603555140000003,0.08815465800000001,0.014186596999999999,-0.02588457,-0.053251362000000003,0.041765019,0.075401715,0.055776899000000005,0.072132812,-0.560689622,-1.42147024,-2.116976595,-3.003734433,1.6473824330000002,1.352200184,-9.650531458,-9.659339775,-9.283623412999999,-9.695755516,-13.65193146,-5.9620071260000005,-6.960253441,-2.109906444,-1450.6254289913923 -796,796,P65Y,0.059737517000000004,0.092076196,-0.244196248,-1.675778328,-2.809710795,0.039512484,0.10855932199999999,0.010915712,0.048510036,0.066164981,0.117987411,-0.18446132399999998,-0.30393117199999997,-1.554575681,-1.796980975,-2.486025448,-3.133396142,1.110789443,0.7382532070000001,-14.72559443,-11.97753706,-14.41857256,-19.43801533,-15.45878616,-12.33506106,-7.680588175,-2.414636544,-1433.4182865805924 -797,797,M66A,-0.018477378,0.015334467,0.015844945,0.023224095,-1.654670825,0.044304058,0.008395577,-0.045350333,-0.074818127,0.006055871,0.024613062999999998,0.042062311,-0.010372422,-0.0022962029999999997,0.048744392000000004,-1.42687073,-1.88247092,0.665805741,1.322857457,-8.612746361000001,-9.629804688,-9.860213493,-9.35600885,-6.553660881,-7.6640438920000005,-6.247542482,-0.555128583,-1431.6329276883043 -798,798,M66C,-0.041226202,0.017245418000000002,-0.003129543,0.009030523,-1.526861034,0.0035425340000000004,-0.060026919000000005,-0.022425484,-0.146891285,-0.027828534,0.062319369000000006,-0.0008979810000000001,-0.005361105,-0.04935892099999999,0.067419967,-1.503323311,-1.550398757,0.723806815,1.322689162,-12.35013934,-12.23689363,-12.48839301,-13.02649379,-10.435170900000001,-13.56374538,-7.758691001,-6.044103914,-1447.3869948266074 -799,799,M66E,-0.04590084,-0.20613688,-1.537494224,-2.19368571,-3.077086547,0.067039456,-0.009428305,-0.082373375,-0.119810341,-0.045585838,-0.36668792200000005,-1.270989557,-1.80399889,-1.9979276590000001,-2.389443761,-2.470649199,-3.683523895,2.7589069189999997,1.251685956,-13.00370005,-13.92857339,-12.7732355,-13.51667011,-10.24239192,-14.55762933,-8.243294148,-6.817865587999999,-1452.7445431384258 -800,800,M66D,-0.040833646,-1.52638438,-1.972504373,-1.978479937,-3.33080682,0.023599262000000003,-0.025637942,-0.05602935,-0.247594145,-1.426013919,-1.62675484,-2.054452452,-1.8905562930000002,-2.076668221,-1.880291652,-3.072268505,-3.5893451339999998,3.351215222,0.901056436,-14.40108427,-14.23587167,-14.45002978,-14.63805569,-11.39648042,-17.28498377,-9.455016926,-9.27429895,-1457.7550846049562 -801,801,M66G,-0.053145705999999994,0.010669431000000002,0.001864735,-0.06405898,-1.892259959,0.055041003,-0.032001964,-0.074289448,-0.065162076,0.034804966,-0.013466104,0.042681817000000004,-0.038952347000000005,-0.06396408,-0.06415388,-1.7294825719999998,-2.055037345,0.7256021359999999,1.3123832340000001,-12.96721904,-12.65463089,-12.38970042,-13.51684748,-10.319788599999999,-15.95512783,-6.823025425,-4.848255533000001,-1441.1374310981482 -802,802,M66F,-0.025169407999999997,0.048467643,-0.0038113279999999997,0.015262598999999998,-0.487952175,0.07727566599999999,-0.022324929,-0.028013887,-0.055781329000000004,0.04607116,0.050864125999999996,0.016816283,-0.024438937999999997,-0.040311711,0.070836909,-0.35208611700000003,-0.6238182329999999,1.300046517,1.8325226419999998,-7.7777883,-7.1223746189999995,-5.873723991,-7.536209502999999,-7.44499865,-10.91163474,-3.45479496,-1.561841817,-1444.1356613873504 -803,803,M66I,0.027529546000000002,-0.030403865,-0.021759397000000003,0.020276405,-0.17614582899999998,-0.05477336,0.02508021,0.029978882000000002,-0.064598962,-0.058242715,-0.002565014,-0.008828951,-0.034689843,-0.034540066,0.075092875,-0.09840518300000001,-0.253886475,1.3503311830000002,2.292463867,-4.471891563,-3.765870277,-4.51866745,-4.700688598999999,-3.424503555,-5.949727936,-4.24406619,-2.3576114319999997,-1454.8833531201817 -804,804,M66H,-0.024175019,0.000533706,-0.014147416999999999,-0.0485973,-1.920554511,0.042019846,-0.000578877,-0.04777116,-0.082013703,-0.009057119,0.010124530999999999,-0.01685438,-0.011440453,-0.059507278,-0.037687321,-1.78621729,-2.054891731,0.906948565,1.3177517220000001,-11.68956298,-10.35392963,-10.24130968,-13.27693059,-9.595164665,-14.98048032,-5.458169513,-3.037527056,-1452.2920941165648 -805,805,M66K,0.013453243,-1.365852074,-2.353720856,-2.4491384999999997,-3.093978709,0.060589000999999996,0.042931791,-0.016025305,-0.20062876600000001,-1.5059725419999999,-1.225731605,-2.244286065,-2.463155647,-2.5217743390000003,-2.37650266,-2.4381933780000002,-3.74976404,0.712534115,-0.959377521,-13.30454448,-13.74884412,-13.64579363,-14.08646209,-10.12295575,-14.91866682,-9.380420642999999,-8.976044596,-1459.6729928790592 -806,806,M66L,0.010496515,0.011515403,0.02121233,0.008152147,-0.054318447,-0.009960666,0.0062425,0.014750528999999998,-0.073227303,0.0037234509999999996,0.019307355,0.033918365,0.008506295,-0.033652615,0.049956908,-0.020482383,-0.08815451,1.216325745,2.462144269,-1.534105042,-1.114103386,-1.735543365,-1.83298275,-0.36744783799999997,-2.6204478680000003,-1.790923645,-0.6264706760000001,-1452.1185088790953 -807,807,M66N,-0.059014943,-0.034475008,-1.2675028959999999,-2.050948181,-3.0302917810000003,0.034619947000000005,-0.042977175,-0.075052711,-0.008511418,-0.03463768,-0.034312335,-1.072011606,-1.462994186,-2.0655032230000003,-2.036393138,-2.981922262,-3.0786612989999997,2.1823411459999997,0.842551809,-14.05437822,-13.42929005,-13.05202569,-14.67120139,-10.83099105,-18.28838294,-9.455016926,-9.27429895,-1453.8343408238143 -808,808,M66Q,-0.023585763,0.024812324,0.02141854,-0.082957833,-2.0392695830000003,0.050383575,-0.003667515,-0.04350401,-0.075899808,0.032253262000000005,0.017371386000000003,0.05655039,-0.013713311,-0.07541945,-0.090496215,-1.760934354,-2.317604812,0.8139777109999999,1.3133996190000001,-9.611465596,-10.95479543,-9.378733978,-9.685070595,-6.582183655,-11.45654433,-5.483093729,-2.453323429,-1454.473400194198 -809,809,M66P,-0.019193346,-0.519333527,-1.693169217,-2.169857775,-3.1022491239999996,0.044302247999999995,0.0013297029999999998,-0.039716394,-0.016076137,-0.42440564399999997,-0.614261409,-1.614595864,-1.77174257,-2.0927435880000003,-2.246971962,-2.8542606669999997,-3.35023758,2.7025196910000004,0.9724709999999999,-11.38778756,-11.95941073,-11.52832517,-12.8295838,-9.15344973,-11.46816839,-6.206685912999999,-3.320250778,-1434.4138826727867 -810,810,M66S,-0.022181653,0.035280097999999996,0.00772585,-1.4834083180000002,-2.363766686,0.017875811999999998,0.000625946,-0.044989250999999994,-0.075959506,0.041143001,0.029417194,0.016819133,-0.001367433,-1.162779884,-1.804036751,-2.170279392,-2.55725398,0.652395837,0.726664005,-10.50641447,-9.624621552,-9.976209557,-11.21477529,-6.906093772999999,-14.810372199999998,-5.282427157,-1.155982599,-1437.139110333752 -811,811,M66R,-0.026070605,-1.2988736570000001,-2.107423854,-2.581857978,-3.001973273,0.070585812,0.00385321,-0.05599442,-0.118329539,-1.349031637,-1.248715677,-2.17522049,-2.039627217,-2.526494978,-2.637220978,-2.795096534,-3.208850012,0.5670582160000001,-0.814341546,-13.55384705,-13.99313988,-13.32657004,-14.23486736,-10.65178967,-15.56286829,-9.455016926,-9.27429895,-1453.0825472860597 -812,812,M66T,-0.018051513999999998,0.025649935,0.018232183,0.006369444,-1.4201589369999998,0.044127829,-0.012861124,-0.023241902999999998,-0.095227956,0.011312359,0.03998751,0.004327924,0.032136442,-0.033258015,0.045996902,-1.4250037009999998,-1.415314173,0.825793265,1.335626323,-7.4558965,-7.432700302000001,-7.462693237000001,-8.288435852000001,-5.184290459,-8.911362647999999,-4.81611863,-1.394418984,-1441.8792279399931 -813,813,M66W,-0.031820963,-0.475738042,-1.636609335,-2.347251439,-3.355591012,0.019395275,-0.021396135,-0.042245791,-0.09466632,-0.40083401,-0.550642074,-1.574982534,-1.698236135,-2.454530799,-2.239972078,-3.274039824,-3.4371421989999997,1.637561852,0.18360102399999997,-13.12873119,-12.91194832,-12.24995651,-12.81023176,-11.83610061,-15.83541877,-8.452370444,-6.928005902000001,-1447.4461150313728 -814,814,M66V,-0.002282773,0.038642623,0.019164912,0.0038475479999999997,-0.09895059199999999,-0.012662831000000001,-0.00591711,0.001351564,-0.129880203,0.023072669,0.054212576,0.032630157,0.005699666,-0.033314116,0.041009212,-0.076054262,-0.121846921,1.458404071,2.473539228,-4.831133493,-4.7538431469999995,-4.989405518,-4.673658211,-3.351921959,-6.386838631,-3.848031878,-2.869577149,-1449.9945342447609 -815,815,M66Y,-0.047952653,-0.016218226999999998,0.011545639,-1.324359782,-2.749518565,0.031386775,-0.028981444,-0.066923862,-0.15042491300000002,-0.006253870999999999,-0.026182583,0.022239459,0.000851819,-0.962782125,-1.6859374390000001,-1.987540639,-3.51149649,2.154303806,1.523136309,-12.07770012,-11.28361041,-10.12142515,-12.26257404,-11.15295093,-15.56794007,-5.329543049,-1.60126592,-1447.2014806666411 -816,816,M67A,0.041274409,0.036463102000000004,0.045381773,0.022448772999999998,-0.004768182,0.039407992,0.019126682,0.06342213599999999,0.08002034400000001,0.025041987999999998,0.04788421599999999,0.070941746,0.0198218,0.019798996,0.02509855,-0.03101826,0.021481896,1.114053806,2.46394564,-5.97247477,-4.994473778,-6.342070435,-5.407921165,-7.179390274,-5.938518196,-2.967422985,2.502068199,-1464.7946768403053 -817,817,M67C,-0.285901642,-0.267102143,-0.16261510199999998,-0.10086360800000001,-0.247812065,0.49139832899999997,-0.34171776200000004,-0.230085522,0.42593016100000003,-0.031570854,-0.502633431,-0.10148486,-0.22374534399999998,0.016894958,-0.218622173,-0.14774885199999999,-0.34787527700000004,1.308930301,2.1096855469999998,-6.574272098,-6.503120781,-5.065774162,-7.185726494,-7.088285362000001,-7.02845369,-3.69076917,1.688979744,-1474.8591928747483 -818,818,M67E,-0.021812481,0.015047528000000001,0.021335597999999997,-1.607073473,-2.184542596,-0.021067369,-0.011352008,-0.032272954,0.025435554,0.049924562,-0.019829507,0.076054445,-0.03338325,-1.442590256,-1.771556689,-2.319767662,-2.04931753,0.520289223,0.6978219370000001,-10.33133629,-8.715245888,-8.069143341,-10.50625233,-13.17024632,-11.19579358,-5.841744052999999,-2.767698938,-1463.7018392528407 -819,819,M67D,0.033463157,0.047099423,0.043524402999999996,-0.058463889000000005,-2.2856503409999998,0.053031825,0.051791422999999996,0.01513489,0.11734982099999999,0.038298975,0.055899871,0.041008891,0.046039915,0.00960841,-0.126536188,-1.87474758,-2.696553101,0.739872275,1.304311377,-8.026353607,-6.453738846,-7.234649277000001,-8.624408463,-9.255814888,-8.563156563,-5.1695256469999995,-2.959472503,-1471.510372634977 -820,820,M67G,0.043927488,0.03253344,0.035252797999999995,0.016393647,-0.03955652,-0.10248272800000001,0.010940336,0.07691464,0.074948537,0.023312764,0.041754116,0.044393691,0.026111904,0.021796616,0.010990678,-0.038998372,-0.040114667,1.182770114,2.426226416,-8.374982378,-7.279254066,-7.356561828999999,-8.660215263,-9.164696807999999,-9.414183922000001,-4.518103308,-1.054475656,-1449.8570393379778 -821,821,M67F,0.083709323,0.064480916,0.050637205,-1.0484920979999999,-2.040629435,-0.002909219,0.09671405699999999,0.070704589,0.039849986000000004,0.04480338,0.084158451,0.04615864099999999,0.055115767999999996,-0.7513720209999999,-1.345612174,-1.892342697,-2.188916173,2.011203346,1.518490046,-8.910077664,-9.151378532,-7.665790993,-7.519482704,-10.58444021,-9.629295883,-6.08864444,-3.720615376,-1462.4621258261614 -822,822,M67I,0.008764232,-0.013699198000000001,-0.030579772,-0.009333499,-1.283578119,-0.09929467,-0.002336164,0.019864628,0.081716572,-0.006034527,-0.021363869,-0.011122473999999999,-0.050037069,-0.019892219,0.001225222,-1.20627444,-1.360881798,0.7750165940000001,1.345960645,-6.617888905,-6.457860329,-7.277482704,-6.5740772089999995,-7.172036583,-5.607987701,-6.863258047,-4.339873322,-1463.2918454189785 -823,823,M67H,0.038810047,0.019228775,0.03650962,0.033339062999999995,-1.556438761,0.022097475,0.009823917,0.067796176,0.03354875,0.022193486000000002,0.016264063999999998,0.035746942999999996,0.037272297,0.018453227,0.048224897999999995,-1.223871674,-1.889005848,0.710296983,1.33981787,-11.04499814,-8.91560154,-8.178470978,-12.86380316,-13.63545108,-11.63166394,-6.083484284,-2.6776702759999997,-1464.5283950786106 -824,824,M67K,-0.019451849,-0.179492392,-1.697063716,-2.467942159,-2.9693657910000004,0.017994551,0.004223585,-0.043127282999999995,0.041115673,-0.071502615,-0.287482168,-1.53379377,-1.860333662,-2.87781195,-2.058072367,-2.412566675,-3.5261649060000004,0.7548908590000001,0.03275763,-11.23512407,-10.45568147,-9.470303573999999,-11.65361331,-13.34326442,-11.25275758,-8.390336279,-7.399047766,-1475.33365962049 -825,825,M67L,0.019574852,0.040355645,0.030829856,-0.0034626120000000003,-0.449230009,-0.08222452599999999,-0.007639496,0.046789199000000004,0.055581853,0.048515153,0.032196137,0.059434201,0.00222551,0.020531066,-0.027456289,-0.334647855,-0.5638121620000001,1.03251495,1.675100715,-2.6141165269999997,-3.161647507,-2.426969795,-2.834422585,-1.92611274,-2.721430008,-3.984816939,-0.278442438,-1462.184876613319 -826,826,M67N,0.020804911000000002,0.049890496,0.040865608,0.014451331000000001,-0.007628561,0.08754204300000001,0.005164126,0.036445696,0.079850242,0.041171217,0.058609774,0.081374525,0.00035669099999999996,0.023875828999999998,0.005026832,-0.007977988,-0.0072791340000000005,1.306073461,2.5405053090000003,-4.073840581000001,-3.47325927,-2.68507943,-4.997464272,-5.637300896,-3.576099037,-3.090289505,-0.5211475870000001,-1469.2407896532677 -827,827,M67Q,-0.028106246,-0.012759333000000001,-0.054587134,0.030859851,-1.0989482940000002,0.10563814199999999,-0.008048122,-0.04816437,0.003375917,0.017606296,-0.043124960999999996,-0.035738608,-0.073435659,0.049900512,0.01181919,-0.664378648,-1.533517939,0.6221822929999999,1.384600014,-8.695790123,-6.868628136,-5.749395653,-9.100534874,-10.88453567,-10.87585629,-4.889685237,0.592894728,-1472.1543064080179 -828,828,M67P,-0.031212695,-1.585740802,-2.344644632,-2.371231389,-2.755756325,0.035931549,-0.012038523,-0.050386865999999995,-0.09502039999999999,-1.6970375359999998,-1.4744440669999999,-2.6498381419999997,-2.039451122,-2.3706070319999997,-2.371855746,-2.604331761,-2.9071808889999997,-0.191687138,-1.1003105359999998,-12.78184855,-12.05338488,-11.65326329,-12.70625984,-14.06418129,-13.43215345,-8.390336279,-7.399047766,-1467.8906290153973 -829,829,M67S,0.023886261000000002,0.022876727000000003,0.031380819,0.005506279,-0.10032247,-0.100766495,0.004342735,0.043429787000000004,0.09135996099999999,0.027069972,0.018683481000000002,0.068164167,-0.00540253,-0.004703409,0.015715967,-0.118357445,-0.082287494,1.4010500940000001,2.322254221,-5.3991242999999995,-4.817881859,-4.96699118,-7.487386116000001,-5.431356705,-4.292005638,-3.3683603910000004,-1.1954267440000002,-1446.9654530445114 -830,830,M67R,-0.02531785,-0.46354768799999996,-1.7714742909999999,-2.217430181,-2.942099013,0.008096506,-0.033688097,-0.016947603000000002,0.035550663999999996,-0.398505349,-0.528590026,-1.747224902,-1.795723679,-2.233910586,-2.200949775,-2.7686653110000004,-3.115532714,1.4266738819999998,0.053629948,-13.62442921,-11.7496193,-11.73669692,-14.00280697,-15.77527293,-14.85774992,-8.390336279,-7.399047766,-1467.8509993357584 -831,831,M67T,0.02386907,0.013818978,0.050287824,0.012335575,-0.062693547,-0.082457579,0.008068071,0.039670067999999996,0.050768912,0.025340032000000002,0.002297923,0.050203033,0.050372614,0.001294481,0.023376668,-0.060961919,-0.064425174,1.301915003,2.424270789,-4.841839943,-5.136262032,-4.113960815,-5.284327385,-5.621512207,-4.053137276,-3.7563991989999996,-1.265326492,-1474.862782876473 -832,832,M67W,-0.012379145,-0.6082582639999999,-1.70148854,-2.163975358,-2.776323366,-0.027639429,-0.005823961,-0.018934328,0.0063556509999999995,-0.549179964,-0.667336564,-1.638668789,-1.7643082909999999,-2.271482508,-2.056468208,-2.505207238,-3.047439493,2.95324871,1.105490899,-11.54143914,-11.13045979,-9.94939344,-10.4027261,-13.54849153,-12.67612483,-7.560676787,-5.021316166,-1472.7546359775588 -833,833,M67V,0.029725297999999997,0.020631657,0.03641298,0.0171589,-0.20580358199999998,-0.09598597199999999,0.009751423,0.049699173,0.023234506000000002,0.024394469,0.016868843999999997,0.064277188,0.008548772,0.017740041,0.016577758999999997,-0.179142174,-0.23246498899999998,1.276108129,2.072543987,-7.083968565,-6.014704688999999,-6.527889762999999,-5.819602493,-6.68602433,-10.37162155,-5.1238031369999995,-2.918821228,-1461.828523225151 -834,834,M67Y,0.059796775,0.002666973,-1.373296289,-2.083085674,-2.869177379,-0.038763141,0.041272863,0.078320686,0.060616347,-0.007079894000000001,0.01241384,-1.415812457,-1.3307801209999999,-2.127807422,-2.038363925,-2.75947216,-2.978882598,2.300551988,0.8052038,-10.50726689,-10.35554903,-9.286521339,-9.392553848,-12.1698839,-11.33182632,-6.259522166,-2.337421261,-1463.3464899524115 -835,835,S68A,-0.000202248,-1.564852456,-1.954407739,-2.211910343,-3.369026655,-0.101700699,-0.015787593,0.015383097,-0.175361047,-1.614956894,-1.5147480180000001,-2.050105244,-1.858710233,-2.104798917,-2.3190217680000003,-3.1558991880000002,-3.5821541210000003,0.64191049,-0.9886236429999999,-8.134089592,-8.392843658,-9.032691727000001,-7.309401955,-7.639710365,-8.295800255,-7.257221025,-7.241972444,-1438.8092964594252 -836,836,S68C,-0.057817662,-0.312383092,-1.8557062830000002,-2.006392902,-2.383237094,-0.00892494,-0.033056525,-0.082578798,-0.024827425,-0.149977208,-0.474788975,-1.6821284580000002,-2.029284107,-1.6933564380000001,-2.319429365,-2.139119008,-2.62735518,3.851583142,2.221694085,-9.060234192000001,-9.875024559,-10.09069373,-7.291008262999999,-9.264254524,-8.78018988,-6.985296891,-6.250451757,-1455.4910557041876 -837,837,S68E,-0.05927591,-2.233223929,-2.6070489340000003,-2.90825055,-3.3581587610000003,-0.10569701699999999,-0.051224825999999994,-0.067326993,-0.284920526,-2.74268016,-1.723767698,-2.792477629,-2.421620238,-2.8037056089999997,-3.0127954910000003,-3.0531735330000003,-3.6631439880000003,1.3066407420000001,-1.679156348,-11.38701376,-11.12287834,-11.64882794,-10.37232729,-11.30070462,-12.49033062,-9.121662103,-11.46630438,-1456.6940216077492 -838,838,S68D,-0.048039022,-1.7857265969999998,-1.9807131869999999,-2.441294185,-3.192232391,-0.091213523,-7.120000000000001e-05,-0.09600684300000001,-0.23719365399999998,-1.95602497,-1.615428223,-2.306852434,-1.654573939,-2.318080414,-2.564507955,-2.868578335,-3.5158864469999997,-0.119915058,-1.2055321490000002,-10.70382442,-10.04070176,-11.36037969,-9.600171989,-10.84679685,-11.67107182,-8.253840805,-8.223226532,-1456.5851892097853 -839,839,S68G,-0.00796827,-1.5669669380000002,-2.1706188859999997,-2.325082074,-2.577396086,-0.108952193,0.00386237,-0.019798909,-0.15758107300000002,-1.567172159,-1.566761716,-2.223350992,-2.11788678,-2.456427722,-2.193736426,-2.404865651,-2.74992652,0.08555689699999999,-1.0517985029999999,-6.75427664,-6.529896132999999,-7.804829971,-5.287579018,-6.818053932000001,-7.331024147000001,-6.142949400000001,-4.624739989,-1439.944031807594 -840,840,S68F,-0.033700172,-1.458205662,-2.3470122780000002,-2.08304701,-2.8595614769999997,0.011023213,0.0039367840000000005,-0.071337128,0.177492533,-1.4948031259999999,-1.4216081969999999,-1.942540603,-2.751483952,-1.7776773240000001,-2.3884166959999997,-2.504266503,-3.214856451,-0.467134612,-0.894969026,-12.54578895,-11.37343853,-14.63639021,-11.00025938,-12.49377458,-13.22508203,-9.121662103,-11.46630438,-1446.6909012626857 -841,841,S68I,-0.19269458,-1.0117956559999999,-1.2529634379999999,-1.089912263,-1.65252998,0.028774228,-0.119899659,-0.265489501,-0.12032555,-1.010223079,-1.013368232,-1.435684161,-1.0702427140000002,-1.071248527,-1.1085759990000001,-1.696380066,-1.608679894,4.020810838,2.55242961,-12.16198637,-10.95683016,-14.67990908,-10.63302402,-11.88560139,-12.65456718,-9.096857065,-11.2243909,-1452.4187610754743 -842,842,S68H,-0.044997535,-1.681058254,-2.523211925,-2.145922842,-2.9732917569999997,-0.064951907,-0.048955023,-0.041040046000000004,-0.22030750899999998,-1.748006327,-1.614110181,-2.83919648,-2.20722737,-2.00532642,-2.286519263,-2.798862389,-3.147721125,0.19589540600000002,-1.137779366,-11.87977776,-10.895183300000001,-12.78887261,-10.56518916,-11.70219681,-13.44744691,-9.121662103,-11.46630438,-1451.40415460011 -843,843,S68K,-0.07462216,-1.75206569,-2.583552916,-2.646193905,-2.945587118,0.047307876,0.052592873,-0.201837193,-0.124353039,-2.0176818709999997,-1.486449509,-2.368509335,-2.798596496,-2.379737315,-2.912650495,-2.62920524,-3.2619689960000002,-0.282312086,-1.152196194,-11.61756844,-10.81608961,-12.26726938,-10.53206288,-11.52999226,-12.94242806,-9.121662103,-11.46630438,-1463.7324872235768 -844,844,S68M,-0.102365858,-2.123151331,-2.5655629319999997,-2.071232245,-2.9275971339999995,0.071377414,-0.09890700699999999,-0.105824709,0.144492273,-1.941047814,-2.305254848,-2.291875278,-2.839250585,-2.303103258,-1.839361232,-2.552571183,-3.302623085,-0.6560267479999999,-1.0809877509999999,-12.11153613,-11.12507278,-13.75415336,-10.70319332,-11.94962793,-13.02563326,-9.121662103,-11.46630438,-1449.7954318542033 -845,845,S68L,-0.083205,-1.753647119,-2.47089468,-2.42659576,-3.0815912030000003,0.015773308,-0.07498041,-0.091429589,-0.115341506,-1.875922633,-1.631371605,-2.828810088,-2.112979272,-2.362916813,-2.490274706,-2.913414734,-3.2497676710000003,-0.238838615,-1.13349804,-12.26772008,-11.20908527,-14.11940754,-10.76326065,-12.40191888,-12.84492806,-9.121662103,-11.46630438,-1444.5019933073781 -846,846,S68N,-0.14518617,-1.5929050569999998,-1.7114079169999998,-1.7533525630000002,-2.096320864,-0.027951397000000003,-0.07203702099999999,-0.218335318,-0.08959093300000001,-1.5653841999999998,-1.6204259140000001,-1.916211664,-1.506604169,-1.626409648,-1.880295478,-2.176907569,-2.015734159,4.232192503,1.904566711,-10.72556892,-10.46418092,-11.26378371,-9.641133247,-10.83990746,-11.41883926,-8.695813849,-9.295201633,-1452.3014485440217 -847,847,S68Q,-0.078034194,-1.779952051,-2.258041605,-2.203640992,-2.89210983,-0.071627005,-0.07738837900000001,-0.078680008,-0.32592159800000003,-1.650285306,-1.909618795,-2.139415468,-2.376667742,-1.974552189,-2.432729794,-2.400111373,-3.384108286,0.58167221,-1.09566034,-11.64948205,-11.04682595,-12.37666847,-10.50819782,-11.47137964,-12.84433836,-9.121662103,-11.46630438,-1450.0572493379004 -848,848,S68P,-0.037315548,-1.602907115,-2.123492316,-2.31595196,-3.316045444,-0.00014879299999999998,0.000589705,-0.0752208,-0.09392557800000001,-1.595146315,-1.610667915,-2.189011828,-2.0579728040000003,-2.258231754,-2.373672166,-2.7885262889999995,-3.843564598,-0.08196982,-1.04648909,-10.30732778,-9.763371368,-11.21548335,-8.941861403999999,-10.02911348,-11.5868093,-8.221768715,-8.223226532,-1465.287350015249 -849,849,S68R,-0.0029233909999999996,-1.619947014,-2.125689924,-2.209027256,-2.991039415,0.061159227999999996,-0.002443422,-0.0034033590000000003,-0.188149492,-1.7272773469999998,-1.512616681,-2.277677166,-1.973702681,-2.243147655,-2.1749068559999998,-2.679702223,-3.302376607,-0.330303709,-1.155592843,-11.48284769,-10.79484264,-12.39500203,-10.14673496,-11.05967715,-13.01798167,-8.719616781000001,-9.281815226,-1458.2811863282695 -850,850,S68T,-0.058477074000000004,-1.4404749119999998,-1.962027363,-2.087137721,-2.7131371910000004,-0.005313177,-0.068223376,-0.048730771,-0.08367688200000001,-1.674975245,-1.205974579,-1.833917183,-2.090137543,-2.213121948,-1.961153493,-2.638681132,-2.787593249,-0.10277578,-1.065789799,-10.4788174,-10.45119284,-10.81506612,-9.903008537,-10.20273798,-11.0220815,-9.121662103,-11.46630438,-1426.3114263415337 -851,851,S68W,-0.055011448,-1.758212307,-2.323615122,-2.158290134,-3.346758972,0.00609287,-0.031404711,-0.078618185,-0.072216837,-1.772041451,-1.7443831630000002,-1.879830866,-2.767399378,-2.037186882,-2.2793933859999997,-2.985624811,-3.7078931319999997,-0.004982928,-1.053660497,-12.38892633,-11.21858965,-13.98785825,-10.87713127,-12.24973358,-13.6113189,-9.121662103,-11.46630438,-1451.4666494396515 -852,852,S68V,-0.074445829,-1.85528656,-2.248222883,-2.333742618,-2.5706664619999997,0.014353853,-0.05177004599999999,-0.097121612,-0.17556096,-2.099742763,-1.610830356,-1.994638272,-2.501807494,-2.227715001,-2.439770234,-2.556364172,-2.584968752,-0.390045621,-1.182754695,-11.87420628,-10.96888941,-14.24413394,-10.32636668,-11.49479956,-12.33684179,-9.121662103,-11.46630438,-1451.6494378359057 -853,853,S68Y,-0.150662618,-1.672354001,-2.376204974,-2.2258615969999997,-2.976799803,0.063606768,-0.054873477999999996,-0.246451757,-0.15653772300000002,-1.6260820409999999,-1.71862596,-2.374849513,-2.3775604340000003,-2.0850474969999997,-2.366675696,-2.635545418,-3.318054188,0.134915438,-1.064738715,-12.67955283,-11.30107623,-14.63900039,-10.94191851,-12.36932961,-14.14643943,-9.121662103,-11.46630438,-1449.740418101661 -854,854,T69A,-0.051391062,0.01358255,-0.37980828899999997,-1.731622716,-2.759739677,-0.009190565,-0.035710917,-0.067071206,-0.039254142,0.018514753000000002,0.008650346,-0.281389363,-0.478227214,-1.500595076,-1.962650355,-2.494313057,-3.025166296,1.4280416180000002,0.810208919,-7.4155885360000005,-7.942192314,-6.8129936220000005,-8.113622443999999,-7.231685112,-6.977449188,-6.6888790039999995,-3.3535770680000003,-1432.662144494243 -855,855,T69C,-0.048560088,0.034575041,0.005548795,-0.66715546,-1.764699631,0.005658811,-0.050667660999999996,-0.046452515,-0.056485386,0.043410375999999994,0.025739706,-0.011442663999999998,0.022540254,-0.370065231,-0.9642456890000001,-1.6141451180000002,-1.915254143,1.5997046369999999,1.453289965,-12.8616503,-13.46987543,-12.34620876,-11.3408198,-13.63874135,-13.51260616,-8.08551869,-4.144376909,-1447.0388978109695 -856,856,T69E,-0.043355236,-0.088709168,-1.57879016,-2.32013121,-3.195768026,0.063972286,-0.044128915,-0.042581556,-0.020549575,-0.037341334,-0.140077001,-1.487317811,-1.670262509,-2.187795065,-2.452467354,-2.625210545,-3.766325507,0.7414875,0.032880436,-15.00102397,-16.20409887,-12.32520458,-14.75901844,-15.33641184,-16.38038609,-11.19462357,-10.07581263,-1465.4737997688353 -857,857,T69D,-0.06617922,-1.387517722,-1.994767061,-2.671883298,-3.2653843989999998,-0.033359528,-0.066500928,-0.065857511,-0.005773021,-1.2358574390000001,-1.539178004,-1.973984384,-2.0155497369999997,-2.71067381,-2.633092785,-2.92624054,-3.6045282569999997,0.417008922,-0.73024674,-14.90185895,-16.39866489,-13.05007192,-13.64129629,-15.00879159,-16.41047008,-9.090674767000001,-5.6023147579999995,-1465.1961943465285 -858,858,T69G,-0.052395547,0.02712598,-1.0709059909999998,-2.045712326,-2.628796876,-0.001301949,-0.046700667,-0.058090427,-0.032376882999999995,0.024617083999999997,0.029634876,-0.867342851,-1.27446913,-1.978020155,-2.113404496,-2.69242739,-2.565166362,2.018730707,0.831264621,-13.94326667,-15.09630908,-11.5605393,-12.86209894,-15.12925217,-15.06813388,-9.044720475,-4.905328363,-1441.1927874404937 -859,859,T69F,-0.071454426,-0.801645658,-1.826176625,-2.111817795,-3.33535459,0.029183406000000002,-0.041299367999999996,-0.101609484,-0.07596699,-0.7054366879999999,-0.8978546270000001,-1.878097444,-1.774255805,-1.915816866,-2.307818724,-2.9764816360000004,-3.694227544,3.178794579,1.23013718,-18.88107499,-20.9565415,-19.76542342,-15.747919400000002,-20.22785215,-17.70763847,-11.19462357,-10.07581263,-1428.6779020996764 -860,860,T69I,-0.058369356,0.021225322999999997,0.020425741,-0.7242212840000001,-1.685743653,-0.067037395,-0.044487495999999994,-0.072251216,0.051696764000000006,0.034887178,0.007563467,-0.024033356000000002,0.064884838,-0.326826682,-1.1216158859999998,-1.8078850830000002,-1.5636022230000002,1.422318999,1.371617045,-12.75686141,-14.76882069,-13.43002761,-12.12079459,-13.01878021,-10.44588395,-6.941189385,-2.532213831,-1449.081536755897 -861,861,T69H,-0.055628356,0.00255992,0.008900143000000001,0.016494293,-1.6643248519999998,-0.006280895999999999,-0.04337642,-0.067880291,-0.049012375999999996,0.018848731,-0.013728891000000002,-3.9899999999999994e-05,0.017840185,0.071385161,-0.038396575,-1.6231869680000002,-1.705462735,0.6168719579999999,1.310989303,-16.43805279,-17.21791068,-15.03825835,-14.16289599,-17.03076466,-18.74043426,-11.19462357,-10.07581263,-1457.3664152952842 -862,862,T69K,-0.04360924,-1.6169576069999998,-2.466101954,-2.2413655130000003,-3.0338366189999997,0.009976759,-0.063254046,-0.023964432999999997,-0.19201864300000002,-1.617659089,-1.616256125,-2.753726042,-2.178477865,-2.490415468,-1.992315558,-2.7059821989999997,-3.361691038,-0.003920767,-1.108293823,-15.38878544,-15.90170132,-14.11138824,-13.64662029,-15.93135444,-17.35286294,-11.18330136,-10.01004175,-1466.8861804557964 -863,863,T69M,-0.022017546000000002,0.055746492,-0.081082689,-1.557463218,-2.478653607,-0.058426799,0.019480575,-0.063515666,-0.026086929,0.053433395999999994,0.058059587,-0.149018517,-0.013146861000000001,-1.4329811280000002,-1.6819453080000002,-2.079911622,-2.8773955910000004,2.719901033,1.768657776,-13.0696115,-14.89475561,-14.13879868,-10.62448895,-14.78542579,-10.90458846,-6.639107642000001,-2.798218868,-1443.8222241243348 -864,864,T69L,-0.062853535,0.038659222,-0.161206981,-1.68770447,-2.3927494819999997,-0.049850517000000004,-0.040785906000000004,-0.08492116400000001,-0.021045629,0.027796179,0.049522265,-0.18375889199999998,-0.13865507,-1.46384512,-1.91156382,-2.402515534,-2.38298343,1.231737466,0.7715207079999999,-14.17809166,-16.31392998,-14.5168845,-12.60187893,-15.85725185,-11.60051302,-6.458622693,-1.683743159,-1437.8382482649758 -865,865,T69N,-0.042633742,-0.084298081,-1.4024180290000001,-2.11060822,-2.71262599,0.037148493,-0.024070145,-0.061197339,-0.035489925,-0.062919052,-0.105677109,-1.2451608859999999,-1.5596751709999999,-2.061031559,-2.16018488,-2.87865828,-2.546593699,2.337664127,0.885571363,-13.67277468,-14.63774023,-12.26824422,-11.90709372,-14.11666958,-15.43412566,-9.62260525,-6.445616418999999,-1455.106887647882 -866,866,T69Q,-0.09942464599999999,-0.306594118,-1.756024139,-2.474744745,-2.361851281,-0.006098008,-0.06501223099999999,-0.133837061,0.061014524,-0.18456717600000003,-0.42862106,-1.583267734,-1.928780544,-2.797078416,-2.152411073,-2.167547106,-2.556155455,1.051096023,0.049428968,-15.16915362,-15.73637352,-13.47614728,-14.12555421,-16.12446354,-16.38322957,-10.2751351,-7.517902377,-1459.8307651919313 -867,867,T69P,-0.042198164,0.032175134,0.042512889000000005,-1.2174905870000001,-2.295937358,-0.004651626,-0.02627112,-0.058125208,-0.0017473920000000002,0.037364278,0.02698599,0.045147605,0.039878172,-0.787598797,-1.647382376,-1.9492901459999998,-2.64258457,2.018297907,1.4927788069999999,-14.32250157,-14.69958135,-13.23689788,-13.66708883,-14.95941074,-15.04952905,-9.697991999,-7.2162177320000005,-1451.5334703149274 -868,868,T69S,-0.050313877,0.036361528,0.004310094,-0.013557221000000001,-1.8406381859999998,0.023486387,-0.04322986400000001,-0.05739789,-0.012397323,0.04717323,0.025549825,0.0013920620000000001,0.007228125,0.009010725,-0.036125166,-1.493955098,-2.187321274,0.586450482,1.31512768,-5.651851439,-5.665791283,-5.252498199,-4.0726995619999995,-5.423524651,-7.8447435,-5.994508122999999,-2.7574258069999997,-1432.9397279582117 -869,869,T69R,-0.033826686,-1.568010718,-1.847191764,-2.254073743,-3.2939003610000004,0.055970303,-0.024817536,-0.042835835,-0.18781065800000002,-1.598592377,-1.537429058,-1.78421811,-1.910165417,-2.324612891,-2.183534594,-3.280542311,-3.30725841,3.238418673,0.7834336009999999,-16.32842711,-17.09460003,-14.5526664,-15.23368475,-16.76773276,-17.99345162,-11.19462357,-10.07581263,-1462.1473578405567 -870,870,T69W,-0.10316216199999999,-1.4231170819999999,-2.231793714,-2.2784861480000003,-3.047111258,0.020761900000000003,-0.070104775,-0.136219549,-0.123547929,-1.47615545,-1.370078713,-2.612222404,-1.8513650240000001,-2.34891183,-2.208060465,-2.8655085560000004,-3.22871396,-0.032727358,-1.023125062,-18.16164438,-19.09954415,-18.25193217,-15.66859653,-19.02078509,-18.76736397,-11.19462357,-10.07581263,-1449.8739202385768 -871,871,T69V,-0.061436789000000006,-0.003162264,-0.10678744400000001,-1.5211143,-2.701354223,-0.03538301,-0.056362498,-0.06651108,-0.012605493,0.000704102,-0.00702863,-0.14021535400000001,-0.073359533,-1.35524768,-1.68698092,-2.2759447230000003,-3.1267637219999997,1.202639397,0.7856481479999999,-8.008597307999999,-9.979805054,-6.967821853999999,-8.193730782000001,-8.962129936,-5.939498917000001,-6.750349907,-0.717806545,-1450.9330443241633 -872,872,T69Y,-0.06860904400000001,-1.469756981,-2.0047377930000003,-2.160560308,-2.899078715,-0.005256922,-0.028609693,-0.108608395,-0.150470713,-1.407109348,-1.532404614,-2.274330989,-1.735144597,-2.011020415,-2.310100201,-2.7037084,-3.09444903,0.622293826,-0.846502567,-18.55613394,-19.74169462,-18.81442363,-14.95372202,-19.39108913,-19.87974029,-11.19462357,-10.07581263,-1438.7560369456187 -873,873,F70A,-0.004612186,0.050537893,0.029291499,0.074641108,-0.061250842,-0.122878254,-0.02403507,0.014810698,-0.021020962999999997,0.00415596,0.096919826,0.034028412,0.024554586,0.07229791099999999,0.076984305,-0.088218805,-0.034282879,1.387359433,2.47471627,-9.085916505,-7.859765274,-9.250729683,-11.84438702,-8.687853409,-7.7868471370000005,-5.254639149,-2.937827005,-1429.8575811292976 -874,874,F70C,-0.05416316,0.027466432000000002,-0.029290387999999997,0.045303395999999996,-0.9926547659999999,0.110081859,-0.03895902,-0.06936729900000001,-0.031885912999999995,-0.010532227,0.065465091,-0.025805582,-0.032775194,0.038891375,0.05171541599999999,-0.794986248,-1.190323284,0.633462878,1.368040107,-9.70662379,-11.02000046,-9.140832565,-10.93694382,-8.813599709,-8.621742393,-6.606571372,-4.25882626,-1445.7246644496918 -875,875,F70E,-0.056775489000000005,0.040870582,-1.310980437,-2.169551935,-2.512372906,-0.042740380999999994,-0.03646489,-0.077086087,-0.065977177,0.10544958199999999,-0.023708418999999998,-1.24202729,-1.3799335830000001,-1.9349251680000001,-2.404178702,-2.7905639069999997,-2.234181904,2.486566607,1.047905239,-14.71197794,-14.73395009,-13.098082400000001,-18.06336001,-14.98381199,-12.68068523,-9.729586578,-9.655179711,-1446.517355832737 -876,876,F70D,-0.057271543,-0.79174894,-2.069277197,-1.796583601,-3.155445205,-0.047648490999999994,-0.036093474,-0.078449612,0.033154694,-0.57545041,-1.008047469,-1.736851801,-2.401702592,-1.6281173340000001,-1.9650498680000001,-2.7847860680000003,-3.526104342,3.443525632,1.668194435,-14.55522802,-13.30727068,-12.345147599999999,-18.45786868,-15.05070731,-13.61514585,-9.729586578,-9.655179711,-1449.0230307397433 -877,877,F70G,-0.032721237,0.042847095,0.037789718,0.083010457,-1.44172006,0.028137942000000003,-0.02689957,-0.038542902999999996,-0.075631217,0.041485304,0.044208885,0.047634815999999996,0.02794462,0.095280264,0.07074065,-1.238525322,-1.644914797,0.633673665,1.3307198,-10.46870049,-11.74912482,-10.64335997,-10.55234083,-11.06647808,-8.332198769,-5.497358964,-4.427234418,-1450.030374742113 -878,878,F70I,-0.034587296000000003,0.06299980200000001,0.095319636,0.090225895,-1.374392405,0.056843967999999995,-0.028542438,-0.040632153,-0.112185149,0.057008267,0.068991336,0.09051747199999999,0.100121799,0.103582009,0.076869781,-1.4097144659999998,-1.339070344,0.681860812,1.323460689,-9.897836623,-9.229908813,-9.516233757,-12.49029485,-10.20848219,-8.044263504,-5.100540272,-0.555050924,-1439.1535003939644 -879,879,F70H,0.052365187,-0.05468426,-0.061522744000000004,8.759999999999999e-05,-0.361345687,-0.125992294,0.00493905,0.099791324,-0.08802128699999999,-0.021398145,-0.087970375,-0.00714718,-0.11589830699999999,-0.058743424,0.05891866,-0.29623535100000004,-0.42645602200000005,1.622583925,2.154389735,-5.177227145,-6.854817268,-3.3937103960000004,-7.376575485,-4.994983261000001,-3.266049316,-4.32094502,-2.801544561,-1450.4759083511308 -880,880,F70K,-0.09174729400000001,0.013684257,-1.700638835,-1.9994873530000001,-2.791579503,0.132760471,-0.056071797,-0.12742279,0.078824803,0.036379177,-0.009010664,-1.827512865,-1.573764805,-1.968655871,-2.030318834,-2.2222346180000003,-3.360924387,0.34407118299999995,-0.05179231,-14.57501632,-16.00471822,-12.35072334,-17.20598676,-14.286319599999999,-13.02733366,-9.712055115,-9.558831591,-1445.2960035577416 -881,881,F70M,-0.04960317400000001,0.008343828000000001,0.008021333,-0.00483853,0.011483928000000001,0.015716142,-0.037810748,-0.0613956,-0.144008633,0.036276567,-0.019588912,0.05604596,-0.040003294,-0.033090605,0.023413546,0.056879904,-0.033912048,1.136844583,2.7325510630000003,-10.55950328,-9.253477477999999,-10.81630177,-12.77338423,-12.02794076,-7.92641214,-5.740083922999999,-2.077452877,-1440.2087575085461 -882,882,F70L,-0.097846925,0.009572438,0.009863398,-0.012687782,-1.86560969,0.005219128,-0.078180837,-0.11751301300000001,-0.066113898,-0.000824729,0.019969604,0.01198491,0.007741886,-0.002924888,-0.022450676,-1.533644555,-2.197574824,0.576926284,1.311734016,-9.765265729,-8.497757942,-10.05480292,-11.72309382,-11.64063809,-6.910035872999999,-6.251001637000001,-4.0886131919999995,-1439.1790193039924 -883,883,F70N,-0.143738536,0.024498221,-0.041049122,-0.089691947,-1.799938512,0.02704759,-0.127806358,-0.159670714,-0.080121026,0.01768104,0.031315402,0.020291068,-0.102389311,-0.011379327,-0.16800456600000002,-1.9396880280000002,-1.660188996,0.589376528,1.297059672,-11.74370806,-12.07736552,-9.340758568,-14.58510719,-12.48960138,-10.22570766,-6.907242301,-3.71449954,-1441.9763695322908 -884,884,F70Q,-0.026713535,0.008806688,0.033625177,-0.07343553900000001,-2.230348399,0.044918568,-0.027686872,-0.025740198,-0.036549313,-0.006957766,0.024571142,0.03689033,0.030360024,-0.03457497,-0.112296108,-1.67222538,-2.788471417,0.7038462590000001,1.313580535,-13.44462861,-12.29040967,-12.13622935,-17.43158511,-14.40741529,-10.95750362,-9.729586578,-9.655179711,-1442.9198238076642 -885,885,F70P,-0.031946444,-1.3527764469999999,-1.83103648,-2.212578135,-2.965079662,0.027865192,-0.015926344,-0.04796654400000001,-0.057243629000000004,-1.326867929,-1.378684965,-1.76035145,-1.9017215090000001,-2.1189784,-2.30617787,-2.3725571469999998,-3.5576021769999997,3.858127207,1.6521478490000001,-14.70290575,-14.9444729,-13.71003355,-17.34600766,-14.61092152,-12.9030931,-9.729586578,-9.655179711,-1452.3694580295123 -886,886,F70S,-0.04805045,0.008869864,0.005711616,0.026640992999999998,-0.364725872,-0.007689261,-0.044295339,-0.05180556099999999,-0.027173334,-0.007830619,0.025570346,-0.009098435,0.020521667,0.01015483,0.043127155,-0.283429078,-0.446022665,1.440751537,2.037717133,-7.657532198999999,-8.193356308,-6.9246042789999995,-8.963448715,-5.77989608,-8.426355614,-4.916078079,-2.176951169,-1444.7269306834787 -887,887,F70R,-0.056427094000000004,-0.24058132,-1.8863248959999999,-1.970961728,-2.691720127,0.068760954,-0.038544672,-0.07430951599999999,-0.04613557,-0.179383879,-0.30177876,-2.04776093,-1.7248888619999998,-2.0018172919999997,-1.9401061640000001,-2.7325172939999995,-2.650922959,0.6920005990000001,-0.187892002,-11.52549287,-10.69684155,-9.880773376,-16.26878606,-11.65253188,-9.128531471,-7.594306696,-5.3751034760000005,-1441.254538282752 -888,888,F70T,-0.078416017,0.03029292,0.011951176,0.021167971,-1.718556765,0.060416740999999996,-0.02801184,-0.128820194,-0.006185274,-0.0040831109999999995,0.064668951,-0.032270879,0.05617323,0.038555007999999995,0.0037809329999999998,-1.552078064,-1.885035466,0.611611968,1.313289089,-11.62546475,-11.24747609,-10.53097983,-15.09091251,-10.89615591,-10.36179942,-7.0658564539999995,-4.696843524,-1421.7671787850559 -889,889,F70W,0.00234178,0.014628795,-0.008423998,0.011956056000000001,-1.0126441720000001,-0.135875169,-0.007808453000000001,0.012492013,-0.050328684000000005,-0.07418519900000001,0.10344278800000001,-0.039816297,0.022968302000000003,-0.054229658,0.07814177,-0.809753244,-1.2155351,0.9592995129999999,1.4371744830000002,-8.765915517,-8.495728889,-9.498482529,-9.916197746,-8.646312972999999,-7.272855446,-6.161588706,-4.976823612,-1460.9782013790682 -890,890,F70V,-0.048794004,0.030406711,0.031028741000000002,0.048168094,-0.037759015,0.024964622000000002,-0.066910194,-0.030677812999999998,-0.052155205,0.028973361,0.03184006,0.036760477,0.025297003999999998,0.052799197,0.04353699,-0.012973468,-0.062544561,1.149243679,2.545344641,-8.432587537,-6.875855286,-8.372665451,-10.90948483,-9.235303627,-6.769628494,-4.603356304,-1.567676314,-1433.3178823580965 -891,891,F70Y,0.009889471,0.064875494,0.026559343,-0.039324537,-2.663858905,-0.196552382,0.005555508000000001,0.014223433,-0.0863798,0.046773045,0.082977942,0.073598556,-0.020479871,0.040202272000000004,-0.118851345,-2.138688566,-3.1890292430000002,0.937490681,1.290382178,-4.196971487,-4.12417453,-3.0817318119999997,-5.967478432,-4.058393135,-3.753079529,-3.645805928,-1.6437094330000002,-1450.220514433924 -892,892,K71A,-0.022341312999999998,-1.3896276230000002,-2.242187535,-2.496077623,-3.5759083,-0.12382122699999999,-0.043061849000000006,-0.0016207770000000001,0.018303515,-1.382603084,-1.396652161,-2.426585325,-2.057789744,-2.289194053,-2.702961192,-3.659214581,-3.492602018,0.041069028,-0.8688970309999999,-7.428212964,-7.521384315,-7.329100876,-7.475908577,-7.37615509,-7.438515961,-7.258929053999999,-6.711949012000001,-1453.28664653562 -893,893,K71C,-0.073174879,-1.501789806,-2.40277975,-2.3903505469999997,-3.20302712,0.22234766399999997,-0.040179269,-0.10617048800000001,-0.069123709,-1.60059405,-1.4029855619999998,-2.102812202,-2.7027472969999997,-2.634427711,-2.146273382,-2.8583202030000003,-3.5477340369999997,-0.023154012,-1.027319465,-9.833668469,-9.787034142000001,-9.912073395,-9.840831795,-9.866564423,-9.761838593,-9.13866872,-11.28944481,-1457.3454605657607 -894,894,K71E,-0.029246166,-1.695551181,-1.9481344680000001,-2.687430361,-2.7905422810000005,-0.059911979000000004,-0.026992081,-0.03150025,-0.13143703,-1.641937749,-1.749164613,-2.3038567430000003,-1.5924121919999998,-2.5344422559999997,-2.840418466,-2.758334749,-2.822749813,0.139259825,-1.0596847329999999,-7.981267249,-7.907765251,-8.226845894,-7.9223906479999995,-8.016172028,-7.833162422000001,-7.856059275,-7.526033717000001,-1469.5389002957381 -895,895,K71D,-0.053353874,-1.8686496369999999,-2.446777334,-2.622723486,-3.26990345,-0.099993119,-0.045352672999999996,-0.061355075,-0.185107603,-2.028146904,-1.70915237,-2.3542737959999998,-2.539280872,-2.7097980460000004,-2.535648925,-2.933690538,-3.606116361,-0.061271992000000004,-1.191931139,-9.821797421,-9.742821655,-9.761632843,-9.858717918,-9.942163338,-9.803651352000001,-9.13866872,-11.28944481,-1459.380098912865 -896,896,K71G,-0.03267641,-1.741220386,-2.133378725,-2.295687834,-3.385171089,-0.062753908,-0.043356255999999996,-0.021996562999999997,-0.146275538,-1.855477228,-1.626963543,-2.35769538,-1.90906207,-2.220304108,-2.37107156,-2.9882646439999996,-3.7820775330000003,-0.222585842,-1.140412311,-9.797629523,-9.791578461,-9.788956367,-9.84127018,-9.823898353999999,-9.742444252,-9.13866872,-11.28944481,-1459.5394971068017 -897,897,K71F,-0.06858913900000001,-1.689206737,-2.1161999,-2.4532557,-2.9164472710000005,-0.11164016199999999,-0.062040106,-0.075138172,-0.209574612,-1.6403918219999998,-1.7380216519999998,-2.3644587230000003,-1.8679410769999998,-1.9418317230000002,-2.9646796760000003,-2.64284547,-3.190049072,0.164857191,-1.107999625,-9.786984508,-9.759945221,-9.778404785,-9.660896065,-9.895395844,-9.840280624,-9.13866872,-11.28944481,-1450.4041322954 -898,898,K71I,-0.01482397,-2.167284589,-2.449879983,-2.335390788,-2.773006099,-0.033942327,0.037021572999999995,-0.066669512,-0.017629088,-2.1218059730000003,-2.212763205,-2.447932866,-2.4518271,-2.201397124,-2.469384452,-2.7263196119999997,-2.819692585,-0.42485301700000005,-1.13637661,-9.816646231,-9.919712357,-9.769868622,-9.803701813,-9.92631575,-9.663632613999999,-9.13866872,-11.28944481,-1461.0909565826878 -899,899,K71H,0.002468864,-1.932019025,-2.086978165,-2.424033964,-3.227846154,-0.09548181,-0.01031781,0.015255538,-0.146226987,-2.0566354419999997,-1.8074026069999998,-2.030579816,-2.143376514,-2.738286584,-2.109781344,-2.564239067,-3.8914532410000002,-0.116763868,-1.160365058,-9.82200435,-9.784632712999999,-9.818676369,-9.92590435,-9.805128197,-9.775680122,-9.13039196,-11.20689,-1461.7439666516148 -900,900,K71M,-0.069685438,-1.734598039,-2.241739698,-2.553219236,-3.0164108069999997,-0.130262465,-0.07062875099999999,-0.068742124,-0.191056935,-1.898107472,-1.571088605,-2.099295628,-2.3841837669999997,-2.454819878,-2.6516185930000002,-2.67871237,-3.354109243,-0.064607945,-1.1558201129999999,-8.659729297,-8.644042053,-8.774832283,-8.8217836,-8.585026459,-8.47296209,-8.127854018999999,-8.205072427000001,-1457.913557050284 -901,901,K71L,-0.043237132000000005,-1.799813527,-2.1332633690000002,-2.413967028,-3.12361636,-0.107937245,-0.032342666,-0.054131597999999996,-0.159364962,-1.833508226,-1.7661188280000002,-2.1596351190000003,-2.106891618,-2.566311891,-2.2616221640000003,-2.69329437,-3.5539383489999996,0.022446297,-1.130619268,-9.458673164,-9.272165161,-9.710671478,-9.479141151,-9.47148465,-9.359903381,-8.76208769,-9.284504038,-1453.9317893213592 -902,902,K71N,0.009434887,-1.4301147280000002,-2.280446826,-2.192749045,-2.8756069639999997,-0.105943152,-0.004832194000000001,0.023701967999999997,-0.081358165,-1.61268255,-1.247546906,-2.592021956,-1.968871695,-2.169394956,-2.216103134,-2.8704087030000003,-2.880805224,-0.19437088800000002,-1.07199181,-9.732415508999999,-9.611261948,-9.731493301,-9.841481155,-9.878447891,-9.59939325,-9.130668229,-11.25349789,-1453.3781241173856 -903,903,K71Q,-0.039866595,-1.8159244909999999,-2.730140602,-2.439560149,-3.053266718,-0.09101500900000001,-0.036805781,-0.04292740900000001,-0.163856803,-1.677580777,-1.954268205,-2.702677674,-2.75760353,-2.456141933,-2.422978365,-2.98106442,-3.125469015,-0.071627646,-1.111363545,-8.445954745,-8.241887138,-8.629492958,-8.43746653,-8.492394394,-8.428532707,-8.157069101,-7.997069885,-1458.3565520867705 -904,904,K71P,-0.05435827,-1.7667637669999998,-2.103727406,-2.365779742,-3.1227864519999997,0.016499536000000002,-0.042646699999999996,-0.06606984,-0.141233902,-1.799285038,-1.734242496,-2.203572508,-2.003882303,-2.240093391,-2.491466093,-2.9530063610000004,-3.292566542,-0.33409351800000003,-1.144157337,-9.810337882999999,-9.853272964,-9.80120916,-9.720756645,-9.853996841,-9.822453804,-9.13866872,-11.28944481,-1449.7697999221273 -905,905,K71S,-0.018584415,-1.5719056569999998,-2.123506915,-2.409903148,-3.743276064,-0.067771768,-0.02312009,-0.01404874,-0.067361863,-1.605658767,-1.538152547,-2.304171563,-1.9428422669999998,-2.5047938530000002,-2.315012443,-3.42765635,-4.058895778,-0.167303383,-1.041359732,-7.956372312999999,-7.867123444,-7.926501854,-7.965756332000001,-8.003749275,-8.018730659,-7.75790133,-7.526033691,-1449.872857797891 -906,906,K71R,-0.074437132,-1.389014437,-2.094399992,-2.26112359,-3.181662996,-0.021993553,-0.07269741099999999,-0.076176853,-0.121209195,-1.32484997,-1.453178904,-2.1199802269999997,-2.068819756,-2.199298065,-2.322949114,-2.7505494919999998,-3.6127764989999998,2.654953805,0.28257444800000003,-7.487875397000001,-7.4284436110000005,-7.592430007999999,-7.420646392999999,-7.530441207999999,-7.467415764,-7.5848181320000005,-7.081301237000001,-1460.190066375304 -907,907,K71T,-0.026357297000000002,-1.6428896590000002,-2.043785169,-2.3016597219999997,-3.0174262830000003,-0.08399859300000001,-0.013035878999999998,-0.039678715,-0.101592363,-1.71301623,-1.5727630869999998,-1.955597071,-2.131973267,-2.010091325,-2.593228119,-2.535013813,-3.499838752,0.11760355300000001,-1.046041142,-6.777715538,-6.723575241,-6.830490097,-6.8930517810000005,-6.7311804120000005,-6.710280159,-6.894332614,-6.444839652000001,-1455.0699641150422 -908,908,K71W,-0.003949216,-1.607717082,-2.110874276,-2.47412411,-2.906241728,-0.048581541,0.02034402,-0.028242451000000002,-0.13167921300000002,-1.665534857,-1.549899306,-2.3438442680000002,-1.877904284,-2.699368518,-2.248879701,-2.92326101,-2.889222445,-0.170433277,-1.103846406,-9.808292342,-9.785322731,-9.757114311,-9.850292557000001,-9.874991295,-9.773740814,-9.13866872,-11.28944481,-1458.680269046221 -909,909,K71V,-0.017826069,-1.626137383,-2.300684566,-2.646604749,-3.2603113180000003,-0.109732287,-0.0021448179999999997,-0.03350732,-0.046109345,-1.683720536,-1.56855423,-2.510449779,-2.0909193530000003,-2.440005297,-2.8532042,-2.663897789,-3.8567248469999997,-0.38716672399999996,-1.08008484,-8.73108681,-8.621626999,-8.831675255,-8.730385429,-8.836264099,-8.635482269,-8.489117626,-8.620431725,-1460.5978925004601 -910,910,K71Y,-0.060175188,-2.0340453000000003,-2.500629086,-2.837684885,-3.0623158289999997,-0.094350034,-0.029031384,-0.091318991,-0.16761011,-2.151610955,-1.916479645,-2.4777378469999998,-2.523520324,-2.532232102,-3.143137668,-2.7561245939999997,-3.3685070639999997,-0.268920477,-1.200743881,-8.729243103,-8.576681099,-8.748501457,-8.913617149,-8.87844381,-8.528972,-8.559992384,-8.219598506,-1460.6198435733095 -911,911,V72A,-0.027805008,-0.015065753000000001,-0.00369984,-0.042274095,-0.856415618,0.059839813,-0.025553332999999998,-0.030056682,0.026489985,-0.027162261,-0.002969245,0.017834445,-0.025234125,-0.031889358,-0.052658830999999996,-0.550051544,-1.162779691,0.834882461,1.46460614,-2.960336475,-1.8283721919999998,-2.903871048,-2.311072868,-3.538372147,-4.219994118,-3.155021867,-0.432795055,-1455.5231465990655 -912,912,V72C,-0.024673567,0.026718226,0.015369262,-0.058745162000000004,-1.496115302,0.056638112000000004,-0.036696621,-0.012650513,-0.006530866999999999,-0.013378896000000001,0.066815348,0.009053057,0.021685467000000003,-0.06154074,-0.055949583,-1.452333778,-1.539896825,0.823601845,1.335695021,-10.09612404,-9.851898949,-8.774846085,-10.73412229,-9.553087067,-11.56666579,-7.795746162,-5.623380455,-1472.2197680368554 -913,913,V72E,-0.227202028,-0.42079340200000004,-1.3713314230000002,-1.4973481069999999,-1.725521981,0.41833993799999997,-0.08809344599999999,-0.36631061,-0.281879642,-0.101826927,-0.7397598759999999,-1.02678006,-1.715882785,-1.110982107,-1.883714106,-1.3097655529999999,-2.1412784080000002,4.016502244,3.16702012,-10.67133559,-10.18014629,-8.616279869,-10.79678746,-10.51672675,-13.24673757,-9.357759313999999,-6.734369282,-1463.5141635155305 -914,914,V72D,-0.019572925,-1.6711509080000002,-2.207037043,-2.211534702,-2.711742599,0.052141238,-0.0076789630000000005,-0.031466886,-0.054383993,-1.579723016,-1.7625788,-2.152493631,-2.261580454,-2.060604419,-2.362464985,-2.73650912,-2.6869760769999997,-0.21665399,-1.02881017,-12.12908635,-11.55562926,-10.06414733,-12.511080699999999,-11.59871064,-14.91586384,-10.1347644,-9.125508624,-1463.3807263965718 -915,915,V72G,-0.030763272999999997,-0.005612139,-0.205865066,-1.8287566919999998,-2.575720423,0.058110992,-0.017503526000000002,-0.04402302,-0.051147686,-0.022759504,0.011535226,-0.19732456899999998,-0.214405562,-1.571030629,-2.086482755,-2.489973378,-2.661467468,1.335659485,0.7634421690000001,-9.329563174,-9.275374893,-7.726531921,-9.360203484,-8.937884239,-11.34782133,-5.852522545,-2.539726214,-1466.9471549484879 -916,916,V72F,0.001824488,-0.011163712,-0.26707993399999996,-1.475531555,-2.5835393509999998,0.023247317000000003,0.038481053,-0.034832077999999995,0.095796151,-0.0043626129999999996,-0.01796481,-0.20738742,-0.326772448,-1.5064333159999999,-1.444629793,-2.404186766,-2.762891935,1.269366205,0.7756560370000001,-9.344027129,-8.169963165,-6.637502655,-12.31546964,-6.7687313,-12.82846889,-5.940527977,-0.874126842,-1468.30120584229 -917,917,V72I,0.028744624,-0.024292395,-0.103479614,0.022198371,-0.507858731,0.020444089,0.027932857000000002,0.02955639,-0.074637816,-0.110457259,0.06187247,-0.095767391,-0.11119183699999999,-0.017706378999999998,0.062103121,-0.343135025,-0.6725824359999999,1.394439741,1.9043568990000002,-5.342679185,-6.329724457,-4.718560226,-5.376194122,-5.984338791,-4.304578331,-6.560786592,-0.82323682,-1468.1258011623286 -918,918,V72H,-0.087132349,0.003906718,-1.058058409,-2.225542541,-2.692277041,0.006191825,-0.078674724,-0.09558997400000001,-0.031509414,0.018055938,-0.010242501999999999,-0.721996415,-1.394120402,-2.248155301,-2.20292978,-2.623030005,-2.761524077,1.6682123869999999,0.62249857,-12.57578015,-11.19113375,-9.099641022,-14.76982511,-11.45620301,-16.36209788,-9.37860367,-7.314857802000001,-1466.5612038881518 -919,919,V72K,-0.38036411700000006,-1.317882749,-1.291299516,-1.4173162000000001,-1.645490074,0.195761894,-0.369435335,-0.39129289799999994,-0.10295909199999999,-0.813031387,-1.822734111,-0.783742011,-1.79885702,-0.867944059,-1.966688341,-1.0667275040000002,-2.2242526430000003,3.623108256,3.069597641,-11.62049921,-11.93941446,-8.963326172,-11.6359828,-11.19290874,-14.37086386,-10.1347644,-9.125508622,-1462.9793442986847 -920,920,V72M,0.05653194,-0.055579535,0.078278454,-1.513848237,-1.892537109,0.108476529,0.035253495,0.077810385,-0.06844824099999999,-0.101826927,-0.009332143000000001,0.134587942,0.021968966,-1.110982107,-1.916714366,-1.610795549,-2.174278668,3.0170069969999997,2.308211273,-7.378028197999999,-7.54708046,-6.271592299999999,-8.296027061,-6.007042952999999,-8.768398216,-5.592804947,-2.672319864,-1462.4203889290802 -921,921,V72L,0.003981852,0.040422772999999995,0.017088116,-0.338428524,-1.964738695,0.01399516,0.011487566000000001,-0.003523862,-0.032616707,-0.004403865999999999,0.085249411,0.010286001,0.023890231,-0.201585423,-0.475271625,-1.62488201,-2.304595379,1.210821138,1.363598483,-5.281452625,-5.695308762000001,-5.22336718,-7.091591789,-2.833224014,-5.563771377999999,-5.342466635,-0.0015935139999999999,-1466.6839823052287 -922,922,V72N,-0.06523045,-0.689742614,-1.608409811,-1.918414887,-2.686179384,-0.023621601000000002,-0.04769343400000001,-0.082767466,0.035343606,-0.560306071,-0.819179157,-2.0624956119999998,-1.154324009,-1.845667664,-1.99116211,-2.345481105,-3.026877662,1.265894446,-0.195496007,-12.11868162,-12.17686385,-10.61537549,-12.70920545,-11.06998328,-14.02198003,-10.1347644,-9.125508619,-1465.0761702479795 -923,923,V72Q,0.08921719,-0.21184798600000002,-1.602352789,-2.134826151,-2.513515023,0.12575556599999999,0.124290885,0.054143494,-0.069440915,-0.28155247,-0.142143502,-1.95983327,-1.244872307,-1.743005322,-2.52664698,-2.2428187630000003,-2.784211282,3.99561871,2.1994367980000002,-10.73527726,-10.52604308,-9.272590675,-10.38185872,-10.21199604,-13.28389776,-8.920950041000001,-6.736501291000001,-1461.1012154477648 -924,924,V72P,0.031310514,0.010357175,0.022961709,-0.003403723,-0.027108305,-0.044071322,0.003343027,0.059278001,0.004056785,-0.024078678,0.044793027,0.01989516,0.026028258,-0.024468275,0.01766083,-0.031011952000000002,-0.023204657000000004,1.319255397,2.5158700880000002,-5.957245757000001,-5.868305099,-4.896244392,-6.102723,-4.982215675,-7.936740616,-4.776044599,-3.079748695,-1464.4013871974312 -925,925,V72S,-0.022299347999999997,-0.010718031000000001,-0.003748603,-0.021408331000000003,-1.4561713019999998,0.013080475,-0.037460104,-0.007138591,-0.059600197,-0.049136424000000005,0.027700363,-0.027279536,0.019782331,-0.000121604,-0.042695057,-1.374223542,-1.5381190619999998,0.741602641,1.332392611,-6.394013899,-5.999102623,-6.190459327999999,-6.6748500139999996,-5.454113898999999,-7.651543632999999,-5.112541195,-3.2991320319999997,-1462.3526897826232 -926,926,V72R,-0.041560241,-1.425340606,-1.985458433,-2.195536282,-2.923710155,0.069975753,-0.056358152,-0.02676233,-0.19734413,-1.481700852,-1.368980359,-2.035988062,-1.934928803,-1.89834136,-2.492731203,-3.097124805,-2.750295505,-0.34987106700000004,-1.102522968,-11.83603248,-11.41886273,-10.46571928,-11.66217704,-11.13658121,-14.49682213,-10.1347644,-9.125508613,-1473.2822453598492 -927,927,V72T,0.026549943,0.024497295,-0.01619889,-0.0032849000000000003,-0.315691669,-0.013390216000000002,0.019502638,0.033597247000000004,0.014809948,-0.010573648,0.059568237999999996,-0.020976098,-0.011421681999999999,-0.016661145,0.010091346,-0.22993074100000002,-0.401452597,1.186718344,1.900478504,-3.799587802,-5.66988588,-2.409797752,-3.104544868,-2.9296091310000003,-4.884101379,-5.368511167,-1.063179863,-1466.4900013445877 -928,928,V72W,-0.091458333,-0.54702568,-1.65047814,-1.776494825,-2.004668698,0.071646465,0.002669673,-0.18558633800000002,0.006185377,-0.479816708,-0.614234651,-1.295625372,-2.005330908,-1.37982742,-2.173162229,-1.578610865,-2.430726531,4.260887365,2.95946835,-10.12354835,-7.398599464,-8.432560318,-10.76323904,-9.454985306000001,-14.56835764,-5.930063173,-2.9853707330000003,-1461.6617542267777 -929,929,V72Y,-0.010121409,-0.759473762,-2.009346254,-1.794742319,-2.713021813,0.049150617,0.02083588,-0.041078698,0.159637271,-0.49451066,-1.0244368640000001,-2.04500488,-1.9736876269999999,-1.8281769319999999,-1.761307706,-2.327990373,-3.0980532530000002,1.1724569329999999,-0.17504751,-11.95632267,-10.69564837,-7.831805557000001,-13.96516068,-9.76371904,-17.52527969,-7.3849042560000004,-3.630981347,-1456.2087368727662 -930,930,L73A,-0.00747685,0.0013868620000000002,-0.0008390580000000001,0.023179191000000002,-0.064115567,-0.002177337,-0.0038499520000000002,-0.011103746999999999,0.030879958,0.018690144,-0.01591642,-0.0007174869999999999,-0.000960628,0.030107198999999998,0.016251182,-0.029505436,-0.098725698,1.100080585,2.476287868,-6.303990211,-5.55218396,-9.067375923,-5.373495941,-7.211072891000001,-4.315822342,-4.93892351,-1.47830732,-1460.462231287267 -931,931,L73C,0.015880851,0.009399786,0.069407413,0.08983670199999999,-0.724250974,0.08075977200000001,0.007424851999999999,0.024336849,0.020648324,-0.054199286,0.072998858,0.025935734,0.112879091,0.031590734,0.148082669,-0.548720807,-0.89978114,0.636938905,1.409077946,-9.659955618,-7.797995674,-11.35941367,-10.11229609,-9.99761972,-9.032452934,-7.381751486000001,-4.118376786000001,-1466.2340490734205 -932,932,L73E,-0.032193585,-0.02060762,-0.45404262700000003,-1.793204936,-2.9475442689999998,0.03620599,-0.013067835,-0.051319334,-0.013497172,-0.064314694,0.023099454,-0.224795628,-0.683289625,-1.458274036,-2.128135836,-2.363855623,-3.531232914,1.42695384,0.820807066,-10.93263555,-9.551456619,-12.55317657,-10.83326192,-11.67215127,-10.05313135,-8.409953718999999,-6.817490654,-1474.630198563682 -933,933,L73D,-0.007161325,-0.037572552,-0.059480887999999996,-1.7524101669999999,-2.994795129,0.044371155999999995,0.019355712,-0.033678362,0.078371161,-0.041122399,-0.034022704,-0.08415726400000001,-0.034804512,-1.276981584,-2.227838749,-2.659684425,-3.3299058319999997,0.947747434,0.750002065,-12.32247162,-11.9773491,-13.23842351,-11.81318225,-13.01174426,-11.57165899,-9.327380676,-9.145311157,-1466.7611443800852 -934,934,L73G,-0.022910036,0.003078483,0.00474493,0.015357063999999998,-1.4639466680000002,0.117438263,-0.007003873000000001,-0.038816197999999996,-0.013563792,0.024383346,-0.018226381,0.013659776,-0.004169916,0.021860716000000002,0.008853411,-1.365790123,-1.562103213,0.525396585,1.318414269,-10.33413128,-9.471213104,-12.52527628,-10.27609064,-11.18234621,-8.215730156000001,-6.109087167999999,-3.937370725,-1466.8208360644057 -935,935,L73F,-0.051340172999999996,-0.038060907000000005,0.010240302,-0.053278238,-0.448223556,0.057962545,-0.047264886,-0.05541546,0.01857118,-0.044439449000000006,-0.031682364,0.04709539,-0.026614786,-0.089058179,-0.017498296,-0.320493345,-0.575953766,1.235423376,1.8019209090000001,-3.997847171,-3.114886307,-5.317045944,-4.878346878,-2.472757217,-4.206199509,-3.6846231680000003,-1.369137634,-1458.8934401026927 -936,936,L73I,0.013393716000000002,-0.021910423999999998,0.005183018,-0.002772592,0.028685084,-0.011751602,0.015317943999999998,0.011469488,0.059829714000000006,-0.075457614,0.031636766000000004,-0.04460121400000001,0.05496725,-0.07473485099999999,0.069189668,-0.059166288,0.116536455,1.5187118819999998,2.566872107,-3.863398647,-3.359509262,-3.370143662,-4.023543053,-4.937362923,-3.626434334,-3.637685438,-2.366266146,-1456.4216919234022 -937,937,L73H,-0.038784991,-0.054103331,-0.041802456,0.0051662,-1.5736759009999999,0.11313851,-0.00031465700000000003,-0.077255325,0.037660522,-0.022373672,-0.08583299,-0.084996899,0.0013919870000000001,0.011999215,-0.001666815,-1.480004994,-1.667346807,0.652300835,1.317587297,-8.057636627,-6.17494558,-8.629783652999999,-9.025859192,-6.544224167,-9.913370544,-5.798620596,-1.613499987,-1465.4565081442706 -938,938,L73K,-0.010680711,-0.650762396,-1.682049234,-1.979532786,-2.943766498,0.021996302000000002,0.020655767,-0.042017188,-0.037517703,-0.562328953,-0.7391958390000001,-1.559326499,-1.8047719690000001,-2.074949559,-1.884116013,-2.883621133,-3.003911863,2.773865428,1.024208257,-10.90491996,-10.24283763,-11.93158435,-10.82577906,-10.87014426,-10.65425448,-9.309240749,-9.05312673,-1476.6109827239998 -939,939,L73M,0.026361935,0.015778941,0.005162353,0.013937103000000001,-0.10406419,0.015761255,0.038722976,0.014000894,-0.028106126000000002,-0.003076427,0.034634307999999996,-0.01479723,0.025121935,0.001616667,0.026257537999999997,-0.108503365,-0.099625014,1.463557431,2.3832024069999997,-3.8949536030000003,-4.028867981,-4.46126902,-3.097025299,-4.819400283999999,-3.068205429,-3.674655188,-2.1659275190000002,-1470.7373921624385 -940,940,L73N,-0.012146497,0.016128115,-0.011162275,-0.45123873299999995,-2.274293433,0.082436202,0.005885708000000001,-0.030178701000000002,0.064841602,0.0076636690000000006,0.02459256,-0.007031764,-0.015292785,-0.271380456,-0.631097009,-2.017068137,-2.531518728,1.326564825,1.329883788,-11.57814435,-10.78497028,-12.560299,-11.80791635,-11.84512508,-10.89241103,-9.327380676,-9.14531113,-1470.1719068945386 -941,941,L73Q,0.017952193999999998,0.050132984000000005,0.05372669099999999,-0.56246493,-1.5095346280000002,0.10094127,0.067236906,-0.031332518999999996,-0.029180005,0.088324625,0.011941343,0.042657294000000005,0.064796087,-0.21946228399999998,-0.9054675759999999,-1.496481189,-1.5225880669999998,1.22819738,1.379497999,-7.777840666,-8.062043747,-8.887946968,-6.881660103,-6.950113655,-8.107438858,-6.069517201,-4.620560756000001,-1469.0204557990655 -942,942,L73P,0.004343286,-0.007240375,-0.000636882,0.022476496000000002,-0.13478089199999999,0.015944083,0.017822153,-0.009135582,0.033989984,0.0036044759999999997,-0.018085226,-0.00033171199999999996,-0.000942052,0.033765008,0.011187984,-0.093665329,-0.175896455,1.372413649,2.351118676,-3.107943782,-2.07627179,-6.2137012789999995,-1.419697609,-3.872377235,-1.9576709980000002,-3.12040644,0.35962014,-1477.2631099021528 -943,943,L73S,0.000995064,0.001674422,0.046240690999999993,0.029119437,-0.986445615,0.09167470900000001,0.033719725,-0.031729598,0.001258126,0.0017033579999999999,0.001645485,0.041780648,0.050700733,0.037246265,0.020992609,-0.782957575,-1.189933655,0.630413013,1.369631712,-7.140405714,-6.049184677,-9.566310616,-7.06583152,-8.120005737,-4.900696022,-4.94164279,-2.414115749,-1468.2906417974737 -944,944,L73R,-0.031299565,-1.411498419,-1.791456507,-1.7873332519999998,-2.580447035,0.079332082,-0.006559110999999999,-0.056040018,-0.065605944,-1.373785609,-1.449211228,-1.6248795059999999,-1.9580335080000002,-1.6763462880000002,-1.898320215,-2.12271821,-3.038175859,4.1975624410000005,2.137672549,-11.73544042,-12.92135189,-12.52713348,-10.42446619,-10.86356042,-11.94069012,-9.327380676,-9.145311135,-1467.752908162307 -945,945,L73T,-0.02059384,-0.02210319,-0.037882938,-0.003443189,-0.755295224,0.076290883,-0.012505761,-0.028681917999999997,0.04430232,0.012275161000000001,-0.05648154,-0.044886672999999995,-0.030879202,-0.036322396,0.029436017999999998,-0.589676411,-0.920914036,0.84076467,1.454027147,-8.12943324,-7.247911446,-10.16799795,-8.10525322,-9.482163506000001,-5.64384008,-6.498701822,-4.111969465,-1460.852029419504 -946,946,L73W,-0.083856435,-0.057215124000000006,-0.274073955,-1.775131512,-2.32208182,0.053937089,-0.058459827,-0.10925304300000001,-0.028436818,-0.044564804000000006,-0.069865443,-0.23640747,-0.311740439,-1.3695474719999998,-2.180715551,-2.3358269,-2.308336739,1.096195878,0.752934832,-8.195167238,-8.506304207000001,-8.69108477,-9.116256325,-6.167587715,-8.494603172,-6.258601733,-2.364015528,-1461.7234349166974 -947,947,L73V,0.010649922,-0.000662605,0.01066079,0.017592247,-0.036333311,0.024543491,0.040681197,-0.019381354,0.10093677300000001,-0.001732438,0.00040722800000000004,0.035228802999999996,-0.013907224,-0.016892077,0.052076570999999995,-0.003946707,-0.068719915,1.338798161,2.641950211,-3.665205779,-3.541421997,-3.576102715,-3.155475105,-4.973662476,-3.0793666,-3.220299495,-2.029691838,-1460.781627566088 -948,948,L73Y,-0.022241227000000002,-0.010332269,-0.018572859,0.030946308,-1.7879032990000001,0.053528957,-0.010439844,-0.034042609,-0.078881971,-0.042480712999999996,0.021816176,-0.006537321,-0.030608397000000002,0.018559193,0.043333422,-1.49313493,-2.082671668,0.565240506,1.314980287,-7.51703033,-5.350079978999999,-9.510669144,-8.141713669,-5.900639427000001,-8.682049431,-5.260362777,-2.2053731180000002,-1457.437479944434 -949,949,L74A,-0.026083738999999998,0.029978357,0.000919232,0.013125423999999998,-1.314976379,0.090138337,-0.01440433,-0.037763147000000004,0.068370891,0.06778332599999999,-0.007826613,0.045364935999999995,-0.043526472000000004,0.049041384,-0.022790536,-1.087167017,-1.54278574,0.486114534,1.327736209,-3.693407797,-4.260184441,-3.815043137,-3.915535469,-2.08899865,-4.38727729,-3.0438684360000003,-0.151715725,-1484.12309954199 -950,950,L74C,-0.046976283,0.000278301,0.048074755999999996,-0.26441253600000003,-2.220898794,0.061852820999999995,-0.015426833000000001,-0.078525733,0.040366661,0.008257166,-0.007700564,0.05752902,0.038620492,-0.126914694,-0.40191037799999996,-1.7447736919999999,-2.697023895,1.070334307,1.33552647,-10.43577897,-12.26280608,-10.29591154,-11.49155151,-8.510739334,-9.617886421,-7.390717887999999,-5.760507144,-1487.178900186438 -951,951,L74E,-0.015613064,-0.037314174,-0.013733456000000002,-1.03588883,-2.636127763,0.116817184,0.010121467,-0.041347594,0.09048369199999999,-0.051749323,-0.022879023999999998,-0.034638888,0.007171976,-0.7322859540000001,-1.339491706,-2.587327256,-2.68492827,1.115791921,0.906526154,-11.51939574,-12.73613544,-10.84682243,-12.51947208,-11.00838402,-10.48616471,-6.964032763,-5.352190643999999,-1486.4905130853876 -952,952,L74D,-0.07107390799999999,-1.2311976759999999,-1.610407898,-1.717094718,-2.735655563,0.060193665,-0.080213897,-0.061933918,-0.130051546,-1.28733037,-1.175064982,-1.8189292080000001,-1.4018865880000002,-1.94425147,-1.489937965,-2.56884385,-2.902467275,4.02536965,1.84501417,-13.86264142,-15.31346387,-13.81455099,-15.13405254,-11.86965215,-13.18148756,-9.359036782999999,-9.351993138,-1490.0950350458734 -953,953,L74G,-0.012887098,0.02541357,-0.752166151,-1.7992008609999999,-2.386275324,0.09701302699999999,0.004027392,-0.029801587,-0.046239639000000006,0.060824659,-0.00999752,-0.525185283,-0.9791470179999999,-1.6709705990000001,-1.9274311219999998,-2.398225322,-2.374325326,1.8824083280000001,0.9262082709999999,-10.94658524,-13.51870602,-11.32702902,-11.08519626,-8.49701841,-10.30497649,-6.250203836,-4.114544375,-1487.5474692278076 -954,954,L74F,-0.036409891,-1.238173072,-1.930240566,-2.450469263,-3.1124248860000003,0.107999068,0.01046337,-0.083283152,-0.032328139,-1.120579137,-1.355767006,-2.12929923,-1.731181901,-1.9993489869999999,-2.901589538,-3.0041526089999997,-3.220697163,0.45837037700000005,-0.680525515,-11.61816316,-12.54386303,-10.86236402,-12.64528864,-11.15732284,-10.88197727,-9.316485112,-9.055397934,-1470.6718073720112 -955,955,L74I,0.00029283099999999996,0.05686352,0.034120258,0.033440691,-1.4735563680000001,0.007313961999999999,0.018889151,-0.018303489,0.092201011,0.064989998,0.048737042,0.061521413,0.006719103000000001,0.081132429,-0.014251047,-0.890846052,-2.056266684,0.554346207,1.3469012219999998,-4.407162672,-6.011362625,-3.0067218860000002,-4.443121979,-4.380247215,-4.194359657,-4.76524526,0.075602475,-1475.621767942328 -956,956,L74H,-0.048783512,-1.050894421,-2.213600792,-2.387818916,-3.487305171,0.10008497400000001,0.033260722,-0.130827746,0.068013912,-0.98865428,-1.1131345609999999,-2.326433092,-2.1007684909999997,-2.3725741080000002,-2.403063724,-3.0763477339999996,-3.898262608,0.23620685600000002,-0.646385682,-15.06440324,-14.64071146,-15.18742181,-16.76523162,-13.73744101,-14.9912103,-9.359036782999999,-9.35199292,-1490.057086332934 -957,957,L74K,-0.052036885,-1.137728428,-1.8541715669999999,-2.182748103,-3.1061430989999996,0.081099724,-0.012510111,-0.091563659,0.13889974900000002,-1.1888439690000001,-1.086612886,-1.975715312,-1.732627821,-2.4989775830000003,-1.8665186230000002,-2.725629954,-3.4866562439999997,-0.145738786,-0.7301690359999999,-14.18143313,-15.03937639,-14.74704433,-14.73900453,-12.29664819,-14.08509222,-9.359036782999999,-9.351993018,-1488.9106015856378 -958,958,L74M,0.03852772,0.018414876,0.039793984,0.019934201000000002,-0.428434117,0.019642165,0.059301875,0.017753565,-0.003559497,0.056668699,-0.019838947,0.006911754,0.072676213,0.031889457,0.007978944,-0.29105058,-0.565817653,1.3655839269999999,1.96527427,-6.142061215,-6.8755814289999995,-6.333085304,-5.72943277,-5.844398032999999,-5.92780854,-5.610253161,-3.6906643260000003,-1467.7573895561509 -959,959,L74N,-0.023085612000000002,-0.152651943,-1.3029033540000001,-1.67389584,-2.8724050119999998,0.05748067900000001,-0.001170295,-0.045000929,-0.013200379,-0.087779278,-0.21752460699999998,-1.488609836,-1.117196871,-2.011872107,-1.335919572,-2.539554474,-3.20525555,2.223362145,0.694219574,-12.30180972,-14.11656486,-12.02350327,-13.26573183,-10.66662369,-11.43662498,-6.922977781,-5.062897311,-1485.9374797916971 -960,960,L74Q,-0.060332145,-0.082856653,-0.5989446310000001,-2.103866252,-3.24294313,0.152911997,0.006017429,-0.126681719,-0.009463001,-0.083989323,-0.081723983,-0.403022395,-0.794866867,-1.40340592,-2.804326583,-2.885330797,-3.600555463,1.707220454,0.927811872,-10.64060712,-11.64856188,-10.78763092,-11.64161214,-9.274302895,-9.85092775,-6.565824771,-2.7276514489999997,-1480.0599947771989 -961,961,L74P,-0.015964399,-0.697350252,-1.830984295,-2.271607042,-2.872337698,0.108075012,0.010181735,-0.042110533,0.014847318,-0.553638824,-0.84106168,-1.9231416069999998,-1.738826982,-2.173402605,-2.369811479,-2.71881374,-3.0258616560000005,1.198603967,-0.153828521,-11.90106272,-13.22783706,-12.90607156,-11.97174718,-10.69229533,-10.70736244,-7.806955522000001,-6.066438327,-1489.5380747627933 -962,962,L74S,-0.003771125,0.008548347,-0.34344615100000003,-1.66620322,-2.599628113,0.092326533,0.02112722,-0.02866947,0.048239239,0.020492923,-0.003396229,-0.277178272,-0.409714029,-1.5718374659999998,-1.760568973,-2.313399654,-2.885856572,1.3868352659999998,0.7854479440000001,-8.341780846,-9.697965408,-8.687616477999999,-8.763693794,-6.339389084,-8.220239464,-4.851743691,-3.4052423739999997,-1492.2163445698097 -963,963,L74R,-0.026515805,-1.628701234,-2.015487388,-2.382380953,-3.126264978,0.070963716,0.003124173,-0.056155782,-0.17012128199999998,-1.698039301,-1.559363166,-2.092110275,-1.9388645009999999,-2.138251291,-2.626510615,-2.908971707,-3.343558248,0.032323347999999995,-1.100965185,-14.31317348,-14.69366666,-14.40202042,-15.49812894,-12.57450899,-14.39754237,-9.359036782999999,-9.351992997,-1485.8533450989053 -964,964,L74T,-0.0032274029999999998,-0.004661313,0.006254917,0.021064031,-1.513027813,0.08937736800000001,0.006498025,-0.01295283,0.03212495,-0.015056663999999999,0.005734039,0.001354727,0.011155107,0.016138991000000002,0.025989071000000002,-1.5138231430000002,-1.512232482,0.8663418829999999,1.3367489959999999,-7.6569819720000005,-9.718582222,-7.500228951,-7.777633392,-6.69412999,-6.5943353039999995,-5.134492989,-3.1684561319999998,-1484.8442945079878 -965,965,L74W,-0.024041267999999998,-1.503617449,-2.154350156,-2.179020532,-2.903445524,0.07156709900000001,-0.019014534,-0.029068001,-0.057690905,-1.57303208,-1.4342028169999999,-1.773637699,-2.535062612,-2.472991228,-1.885049835,-2.398613605,-3.4082774430000002,-0.6805542990000001,-1.101304165,-13.11447907,-13.5965399,-13.11915235,-14.031956699999999,-12.02631542,-12.79843099,-9.359036782999999,-9.351992994,-1485.461213949602 -966,966,L74V,0.0007499410000000001,0.028167892000000003,0.016143763000000002,0.03207235,-0.23273484,-0.006218969,0.010387123,-0.008887241,0.03538782,0.056391283,-5.550000000000001e-05,0.024151551,0.008135974,0.051911165999999995,0.012233533000000001,-0.186640429,-0.27882925,1.218678127,2.018171883,-3.903289162,-4.606488365,-3.1998925860000003,-3.62885775,-4.816596825,-3.264610283,-3.6769733610000004,-0.336897099,-1477.3286238703877 -967,967,L74Y,0.010092519,-1.554455648,-1.841688992,-2.5119944469999997,-2.935389443,0.061216791,0.056889062000000004,-0.036704025,-0.062648251,-1.8210864690000002,-1.2878248270000001,-1.908987808,-1.774390175,-2.052038836,-2.971950057,-2.8807512,-2.9900276860000004,-0.198091538,-1.0927561000000001,-13.34446195,-13.75930566,-13.0528546,-14.15982388,-11.90029561,-13.85003001,-8.664891979,-6.830301298999999,-1476.5327466269955 -968,968,C75A,0.046741127,0.053629460999999996,0.006241079,0.0057100269999999995,-0.124974444,0.034996118,0.030469565,0.06301268900000001,0.139065715,-0.012971875,0.120230796,-0.042896697000000004,0.055378854000000005,0.036787527,-0.025367472999999998,-0.151809544,-0.098139343,1.382163228,2.234419145,-6.021995252999999,-6.537822807,-6.683725204,-6.028494697999999,-5.886421173,-4.973512383,-4.945969968,1.879301736,-1446.099217148032 -969,969,C75E,-0.042069892000000005,-1.244999978,-1.889743288,-1.905157077,-2.657888088,0.10634143,-0.022570512999999997,-0.061569270999999995,0.137282569,-1.2037028490000001,-1.286297107,-1.7118000619999998,-2.067686514,-1.5438922519999998,-2.266421902,-1.8661115469999998,-3.449664629,4.0553235139999995,2.1709357540000003,-15.37273278,-16.4327984,-14.13451217,-18.20066129,-15.43410025,-12.66159178,-11.23350191,-7.992037776,-1455.787869965192 -970,970,C75D,0.002994453,-0.452667152,-1.54478751,-2.430277335,-2.621082525,0.103964689,0.010711497,-0.004722591,0.277161655,-0.355898185,-0.5494361179999999,-1.45691201,-1.63266301,-2.162130964,-2.6984237060000003,-2.037192227,-3.2049728230000003,3.8259844089999997,2.155372264,-16.14690484,-16.40199549,-16.58117992,-18.74674195,-16.38843601,-12.61617081,-11.23350191,-7.992037807999999,-1457.760215839371 -971,971,C75G,-0.009012161,0.050104729,-0.021442209,-0.008585221,-1.053258683,0.034990562,-0.012263773,-0.005760548000000001,0.12939405699999998,-0.007543584,0.107753042,-0.045917215,0.0030327970000000003,0.010505081999999999,-0.027675522999999997,-0.6541225420000001,-1.4523948230000001,1.245417445,1.628211047,-10.04001369,-10.08453535,-9.301021271,-10.29080714,-12.48466212,-8.039042563999999,-6.099015379,-1.0305117940000001,-1455.61802890338 -972,972,C75F,-0.016512075,-1.544501752,-2.056827474,-2.148746198,-2.8395513880000003,0.085389886,-0.01170523,-0.021318919,0.00275414,-1.59655816,-1.492445344,-2.091291412,-2.022363535,-1.8556318180000002,-2.441860578,-2.508844332,-3.170258444,0.362554831,-0.9560033990000001,-11.81073969,-12.03612736,-9.764941817999999,-14.317552599999999,-13.13954972,-9.795526947,-7.994391099,-2.732038677,-1456.5303789549507 -973,973,C75I,0.081882041,0.063593051,0.015331001,0.031988828,-0.9554388979999999,-0.019458535,0.081873882,0.0818902,0.060953173,0.009901489,0.11728461300000001,-0.010365296,0.041027298,0.042590543,0.021387112000000003,-0.600752753,-1.3101250420000001,0.7291329940000001,1.424116776,-13.22884645,-13.87663499,-11.1798395,-17.00764029,-14.02025236,-10.0598651,-7.755471947,-1.896905193,-1448.0980138839222 -974,974,C75H,0.003912772,-1.3794876569999999,-1.9538415519999999,-2.181696159,-3.2950503689999997,0.130034062,0.020986862000000002,-0.013161319,-0.17733498,-1.497816966,-1.261158348,-1.8905207609999999,-2.0171623419999998,-2.1697709819999997,-2.193621335,-3.1697709819999997,-3.420329755,0.644613288,-0.900141399,-14.25985871,-16.48898833,-14.06549768,-14.329876800000001,-15.47977629,-10.93515446,-11.23350191,-7.992037793,-1460.3961540032178 -975,975,C75K,0.002156791,-1.7150590890000001,-1.683259221,-1.9844127269999998,-3.147459253,0.134443809,0.016563908999999998,-0.012250327,0.127758999,-1.802923854,-1.627194324,-1.736989799,-1.629528642,-1.636028779,-2.332796675,-2.715210025,-3.5797084810000004,3.9937752110000004,1.6557936130000002,-15.55784837,-16.05559567,-14.87052335,-17.97863459,-15.98027707,-12.90421117,-11.23350191,-7.992037809,-1466.1010525599122 -976,976,C75M,-0.032038209,0.055273305,-0.018830402,-0.31442765100000003,-1.655535905,0.12565421599999999,-0.037707487000000005,-0.026368931,0.003003806,0.011416625,0.099129984,-0.021691368,-0.015969436,-0.08459902400000001,-0.544256277,-1.77635638,-1.534715429,0.86187126,1.3156199659999999,-14.98349964,-15.080151,-11.95112576,-20.36936446,-14.99597459,-12.52088241,-7.630219326000001,0.41384154700000003,-1447.2989947046153 -977,977,C75L,0.016727476,0.063849148,0.014088865,-1.091201824,-1.8691398909999999,0.060973045,0.02710089,0.006354060999999999,0.107230705,0.01812128,0.109577016,-0.007874999,0.036052729,-0.650956525,-1.5314471219999999,-1.884961893,-1.8533178890000002,1.9023422269999999,1.4756038219999998,-14.08618493,-15.04729922,-10.56240178,-20.47826015,-14.96135421,-9.381609261,-8.059922164,1.05815916,-1447.8276952211745 -978,978,C75N,-0.01472233,-0.032952449,-1.252335921,-1.7171294369999999,-3.2335736330000002,0.1187934,0.007281482,-0.036726141000000004,0.175704015,0.00902519,-0.074930087,-1.2088876290000001,-1.295784213,-1.5033778169999998,-1.930881056,-2.950535848,-3.516611418,2.469540133,1.19706792,-14.056019199999998,-14.51755788,-14.74995905,-15.02417044,-14.9602105,-11.02819812,-8.837204836,-2.621569283,-1456.2771215476096 -979,979,C75Q,0.0005599719999999999,-1.078237665,-1.740257823,-2.392133641,-3.0679572189999997,0.133072744,-0.005513237,0.00663318,0.074472628,-1.02052091,-1.1359544190000002,-1.847376886,-1.6331387590000002,-1.883589059,-2.900678222,-2.55259584,-3.583318597,3.206350552,1.170659143,-14.59543297,-14.65206615,-13.97835094,-17.88962863,-14.89940788,-11.55771124,-8.673551272000001,-3.019107175,-1456.4376667845063 -980,980,C75P,-0.006089855999999999,-1.308213605,-2.087607773,-2.350018806,-2.9637010339999996,0.12799376699999998,0.0031021490000000002,-0.01528186,0.008079928,-1.359678203,-1.256749007,-2.21293937,-1.962276175,-2.292958529,-2.407079083,-2.7619618939999997,-3.165440173,0.03790081,-0.8291576159999999,-15.69223567,-15.90535382,-15.42069778,-17.9688344,-15.91687516,-13.24941718,-11.23350191,-7.992037759,-1464.0629555559717 -981,981,C75S,0.013160894,0.051938005,-0.008555905,-0.023008404,-1.618066015,0.099583343,0.018974801,0.007346986,0.036206558,-0.033574772,0.137450782,-0.028859652000000003,0.011747843000000001,0.041303692,-0.08732050000000001,-1.6513899969999999,-1.5847420319999999,0.447381893,1.304622815,-8.195389909,-8.367662445,-8.270373199,-8.237214943,-9.456881699,-6.644817261,-6.359603077999999,-1.030224062,-1452.1323267188855 -982,982,C75R,-0.010354531,-1.4101480990000002,-1.852716616,-1.9839925969999999,-2.91011735,0.134217501,-0.012279035,-0.008430027,-0.072560264,-1.5409473930000002,-1.279348804,-1.6487633819999998,-2.056669849,-1.839591701,-2.128393492,-2.942254043,-2.8779806569999997,3.648520262,1.3990449969999998,-15.72674646,-15.61574667,-15.15561286,-18.98158174,-15.87285349,-13.00793752,-11.20940465,-7.9349730229999995,-1467.4234350933693 -983,983,C75T,-0.0014450770000000001,0.05576981599999999,-0.009663600999999999,0.01817083,-1.171416675,0.104844254,-0.010699139,0.0078089859999999995,0.040319068,0.020604023,0.090935609,-0.010773875,-0.008553326,0.08783506199999999,-0.051493402,-0.849231587,-1.493601763,0.6147110370000001,1.359127406,-10.06911689,-10.21140649,-10.41581057,-12.10150461,-8.560587173,-9.056275604,-7.139915716,-2.103690215,-1451.605203634128 -984,984,C75W,-0.011349745,-1.422312749,-1.636064596,-1.759551568,-2.412726065,0.116880579,-0.0034103640000000004,-0.019289126,-0.072115872,-1.35645951,-1.4881659880000002,-1.490097811,-1.78203138,-1.603016611,-1.916086525,-2.468318037,-2.357134093,4.041460235,2.0570221319999997,-15.65972502,-16.03973476,-13.98582176,-19.11966448,-16.32206633,-12.83133775,-11.23350191,-7.992037787,-1469.9780341591686 -985,985,C75V,0.027750647000000003,0.044840223,-0.002847877,0.030028576,-0.262256631,0.046313754000000006,0.009275872,0.046225422,0.123543642,-0.019944771,0.109625217,-0.047027432,0.041331678999999996,0.046571937,0.013485215,-0.229096412,-0.295416849,1.133656501,1.842978875,-9.734516252,-10.000636300000002,-8.49402919,-13.68894885,-10.242230900000001,-6.246736015,-5.209353603,0.309955902,-1459.0065016015433 -986,986,C75Y,-0.01161151,-1.423035694,-2.098222631,-2.128243143,-2.982064465,0.108933845,0.005924393000000001,-0.029147412999999997,-0.095825071,-1.493940291,-1.352131096,-2.206157487,-1.990287775,-1.769404365,-2.48708192,-2.230135203,-3.7339937260000005,4.220120555,1.789117237,-13.13671996,-14.49208458,-11.170602,-14.55326479,-14.46130765,-11.00634081,-10.41093462,-5.502652412000001,-1460.7769379988313 -987,987,G76A,-0.000738163,-0.001160087,-0.018194826,0.001006891,-0.006424416999999999,0.018457521,-0.029481987999999997,0.028005662999999997,-0.065810954,-0.021910584,0.01959041,-0.035236644,-0.001153007,-0.056300585,0.058314367,-0.008636806,-0.004212027,1.304413005,2.549351083,-1.200531851,-0.024408241,-1.85162513,-1.303297012,-1.359960396,-1.463368477,-2.099228852,1.087358853,-1442.3068320238963 -988,988,G76C,-0.198757879,0.002186972,-0.034950044,-0.007290336,-1.115576811,0.071541575,0.034835408,-0.432351165,-0.08730112,0.007747121,-0.0033731779999999997,-0.012986836000000002,-0.056913252000000004,0.010538479,-0.025119151,-1.329702596,-0.901451025,0.7013155659999999,1.33133805,-9.87600731,-8.467379417,-10.86103766,-10.10920348,-8.510099426,-11.43231657,-7.132300718,-2.871840378,-1435.7166516636498 -989,989,G76E,0.008772829000000001,-0.916709565,-2.03972138,-2.264288271,-3.0537558010000003,-0.058138796,-0.039724711,0.057270367999999995,0.228247592,-0.9332373759999999,-0.9001817540000001,-2.251976209,-1.82746655,-2.7883614239999996,-1.740215118,-2.974592315,-3.132919287,0.059159830999999996,-0.635101906,-11.07087691,-9.048050613,-11.99926998,-11.88263485,-9.3270019,-13.09742722,-9.05037166,-5.046374088,-1445.2241683225147 -990,990,G76D,-0.028952877000000002,-1.01935933,-1.624557009,-1.8726232230000002,-2.3423340930000003,-0.001329793,-0.010277066,-0.047628687,-0.133725183,-0.887388145,-1.151330515,-1.617526534,-1.6315874830000001,-1.781525845,-1.963720601,-2.532028165,-2.15264002,4.170725486,2.274669865,-12.00406741,-9.90292691,-13.38555005,-12.335614300000001,-10.23137534,-14.16487047,-8.951541506,-4.53808911,-1446.4494454110973 -991,991,G76F,-0.23407093199999998,-0.006641146999999999,-0.047276712,-0.503509116,-1.789810329,0.013959386,-0.052669605999999994,-0.415472257,0.007964035999999999,-0.033884149,0.020601856,-0.03339487,-0.061158554000000004,-0.34325366799999996,-0.663764563,-1.7233509059999998,-1.856269751,1.541912824,1.4087742769999998,-13.38580712,-9.913575202999999,-18.05843806,-13.84785667,-9.932236182999999,-15.176929500000002,-6.994403717999999,-3.0145902319999998,-1435.65508238459 -992,992,G76I,-0.10119651699999999,0.04816233599999999,-0.00374222,-0.18153645300000001,-1.8140708330000002,-0.013149393,0.00211033,-0.204503364,-0.018841866000000002,0.030061694,0.066262977,-0.006485805999999999,-0.000998633,-0.073479802,-0.289593104,-1.779046382,-1.8490952840000001,0.919501268,1.31834731,-12.07713985,-9.643192925,-17.36902167,-11.99789848,-8.201432404,-13.17415376,-5.730877222,-0.150529824,-1431.6478779399768 -993,993,G76H,-0.134159257,-0.018706078,-1.313328212,-1.9076673240000002,-3.483680472,0.027627272,-0.032598102000000004,-0.23572041100000002,-0.115415485,-0.006670616999999999,-0.030741539,-1.210740224,-1.4159162,-1.988569745,-1.8267649030000002,-2.9877139919999998,-3.979646952,2.3801314540000003,0.9578654520000001,-12.87813787,-10.75860352,-14.54335578,-12.44305228,-10.47151653,-16.17416124,-9.045547994,-5.442607147,-1443.0837409947999 -994,994,G76K,-0.113014976,-1.515354415,-2.5780437259999998,-2.536526207,-3.35351752,0.015415391,0.009617812,-0.235647763,-0.017333373,-1.615286692,-1.415422138,-2.786422804,-2.369664648,-2.845686764,-2.2273656490000002,-3.031917655,-3.6751173839999995,-0.61353004,-1.061962419,-13.21164809,-11.23691766,-14.24152084,-13.74595574,-11.0989102,-15.73493602,-10.62194635,-8.459220224,-1450.1696609170176 -995,995,G76M,-0.111854985,-0.017873828,-0.072054776,-0.03370548,-1.799435365,0.005460085999999999,-0.017291178,-0.206418792,0.064522814,-0.017806983999999998,-0.017940672,-0.058796838,-0.085312714,-0.081806616,0.014395656000000001,-1.609013342,-1.9898573869999998,0.941426503,1.332580026,-10.1585078,-8.655023177999999,-12.81938037,-12.76938689,-5.755202675,-10.79354589,-6.925766167000001,-0.9423665609999999,-1428.1045052022673 -996,996,G76L,-0.18781035,-0.010261449,-0.052465517,-0.267438362,-1.685606461,0.023415573999999998,-0.045727101,-0.329893598,0.048865083,-0.016494476,-0.004028422,-0.06234852,-0.042582514,-0.20654392,-0.328332803,-1.693156121,-1.6780568009999999,1.249992733,1.361508748,-12.21902982,-8.925948875,-15.86740022,-14.52306777,-7.54232045,-14.2364118,-7.04125587,0.141392842,-1425.093580815941 -997,997,G76N,-0.134887876,-0.61516894,-1.880766075,-2.173751946,-3.3637265419999998,0.096539001,-0.034271306,-0.235504445,0.034158271000000004,-0.469958948,-0.760378931,-2.0296276,-1.731904549,-1.912800302,-2.43470359,-2.877182442,-3.850270642,1.201050117,-0.14749067,-11.42889529,-10.39482754,-12.38905901,-11.5962772,-9.627952705,-13.13635999,-8.978125014,-4.971853758,-1444.1641065687872 -998,998,G76Q,-0.161950913,-0.351404195,-1.60826415,-2.0440452209999997,-3.35474197,0.025706503999999998,-0.066368631,-0.257533195,0.038316126,-0.240816258,-0.46199213100000003,-1.469944317,-1.746583983,-1.927148286,-2.160942155,-3.016469163,-3.6930147769999997,2.695028868,1.096259539,-12.56167703,-10.26981557,-13.87873647,-13.74278053,-10.28445824,-14.63259434,-9.757290569,-6.103613039,-1440.8468230138533 -999,999,G76P,-0.125741076,-1.242940786,-2.095809735,-2.371980644,-3.236796638,0.0435326,-0.024767721,-0.22671443100000002,-0.1206714,-1.205087431,-1.2807941409999999,-2.169230598,-2.022388872,-2.351211835,-2.392749453,-2.9054195110000003,-3.568173764,0.807129804,-0.6968215409999999,-12.63899756,-10.4596858,-14.55797478,-13.211150400000001,-11.13223648,-13.83394034,-10.62194635,-8.459220224,-1450.490029124543 -1000,1000,G76S,-0.148380241,0.0028768170000000003,-0.035051833,0.007652341,-0.032136065,0.021518844,0.0011806660000000001,-0.297941148,-0.018531835,-0.000828168,0.006581801,-0.027534699,-0.04256896599999999,-0.039597059,0.05490174,-0.048974101,-0.015298029,1.178277762,2.260932028,-5.318448616,-4.54477906,-5.963392128,-5.16715947,-4.59249707,-6.324415352000001,-4.508262633,-1.755396225,-1440.1716144247912 -1001,1001,G76R,-0.13468666099999999,-1.573394212,-2.063019504,-2.2769917459999998,-3.250447668,0.047713788,-0.032776549,-0.23659677199999998,-0.14671691,-1.750179799,-1.396608624,-1.9793078569999998,-2.146731151,-2.369565037,-2.184418455,-3.400893967,-3.1000013689999997,-0.062491885,-1.110049036,-13.42546097,-10.79571595,-15.16512668,-14.63967319,-10.77531603,-15.75147298,-10.62194635,-8.459220224,-1442.9419132447802 -1002,1002,G76T,-0.117080549,-0.008849978,-0.019513138,0.025075984,-1.521995719,0.040666997999999996,-0.023051415,-0.21110968300000002,-0.045944066,0.034077496,-0.051777452,-0.010705431000000001,-0.028320845,0.004474556,0.045677412,-1.3440593090000001,-1.6999321280000002,0.64031566,1.325629399,-8.247744933,-6.718817871000001,-10.2868671,-8.805021767000001,-6.865672493,-8.562345436000001,-6.459458242999999,-2.48513455,-1430.876111830119 -1003,1003,G76W,-0.207987571,0.017081838000000002,-0.035151501,-0.274966587,-1.716033837,0.048832404,-0.01063423,-0.40534091200000005,0.013977023,0.040872495,-0.00670882,-0.0008705389999999999,-0.069432462,-0.154467089,-0.395466084,-1.739280912,-1.692786761,1.097686333,1.336201203,-13.229323499999998,-10.44728798,-16.7906634,-14.16896783,-10.30122847,-14.43846983,-7.738709739,-3.211624431,-1449.0848207455128 -1004,1004,G76V,-0.00396612,0.017771211999999998,-0.024386902000000002,-0.41734165799999995,-1.887239644,0.022038914,-0.017859548,0.009927309,-0.080552931,0.01111713,0.024425292999999997,-0.022574492999999998,-0.026199311,-0.281410809,-0.5532725070000001,-1.7178934030000002,-2.056585884,1.39720832,1.383527699,-10.13630155,-7.92838829,-15.16519548,-9.837261543,-6.605335571,-11.14532687,-7.315529146,-0.05330168,-1434.6928505054675 -1005,1005,G76Y,-0.275535708,-0.007914146,-0.05184862,-0.603999159,-1.7525129000000002,-0.023435333,-0.124975431,-0.426095984,-0.041165982000000004,0.011095553000000001,-0.026923845,-0.012229861000000002,-0.091467378,-0.429509287,-0.77848903,-1.735854781,-1.769171019,1.631429035,1.433211156,-13.36634782,-10.45146325,-17.81374196,-12.80981652,-9.81697261,-15.93974477,-7.690368363999999,-2.654338128,-1440.0762867918238 -1006,1006,A77C,0.037604814,0.015472763999999998,0.004788188,-0.00573169,0.031666339,0.021386352999999997,-0.015816748999999998,0.09102637699999999,-0.22702135199999998,0.003102691,0.027842837000000002,-0.059651797,0.069228172,-0.046057235999999994,0.034593857,-0.00269428,0.066026958,1.163389478,2.4501491090000003,-6.687918579,-6.873618767000001,-8.53809726,-6.583049622000001,-6.898452515,-4.546374733,-4.518973297,-3.728902113,-1465.2110155480914 -1007,1007,A77E,-0.020805263,0.022256052999999998,0.037595676,-0.011047973,-1.10575645,0.033872913,-0.030346953,-0.011263573,-0.20515938,0.109127125,-0.06461502,-0.00209269,0.077284041,-0.036537167999999995,0.014441223000000001,-0.882304339,-1.329208561,0.802578173,1.386337547,-6.872925688,-5.528636932,-6.50172403,-9.387667191,-6.239468391,-6.707131897000001,-4.947344413,-1.374890572,-1454.1625633933581 -1008,1008,A77D,0.036566997999999996,-0.025913877000000002,0.044084167,0.016677015,-1.23474708,0.031479705,0.02119271,0.051941285,-0.237047685,-0.009449233000000001,-0.04237852,-0.028319379,0.116487712,-0.041325651,0.07467968,-0.803485109,-1.6660090509999999,1.208150076,1.523293688,-8.96999187,-7.984231643999999,-9.527714096,-10.84476405,-7.640491097000001,-8.852758469,-6.157526356,-5.308886177,-1454.3035942013375 -1009,1009,A77G,0.035843381,-0.015141845,0.002624282,-0.004488878,-1.1522916859999999,0.059663814,-0.014576562,0.086263323,-0.259007922,-0.006651539000000001,-0.02363215,-0.062502086,0.06775065,-0.061004575,0.052026819,-0.889494518,-1.415088854,0.958543602,1.418953336,-5.123640797,-4.924544571,-5.048627831,-5.914195175,-5.45094133,-4.279895081,-3.806464828,-2.882959615,-1460.0377964531071 -1010,1010,A77F,0.057450019000000005,-0.048037249000000004,-0.032784544,-0.039051586,-0.047762399000000004,-0.036731018,-0.008953301,0.12385333800000001,-0.407485327,-0.071891513,-0.024182985,-0.065785487,0.000216399,-0.140964595,0.062861424,-0.105126731,0.009601933,1.402876335,2.227808267,-9.728875562999999,-9.167750801,-12.35118193,-10.84643547,-9.122790862999999,-7.15621875,-4.1253721269999994,-3.792054397,-1467.0371994180605 -1011,1011,A77I,0.006484655,-0.014691527,-0.008791756999999999,0.021222737999999998,-0.447714455,0.00247353,-0.030787515,0.04375682400000001,-0.28745718800000003,0.058541580999999995,-0.087924635,-0.015839211000000002,-0.001744302,0.005720866999999999,0.036724608,-0.289412826,-0.606016083,0.938011716,1.6661695230000002,-8.236519081,-6.450390082999999,-9.371478874,-10.40665878,-7.827270942999999,-7.126796722000001,-5.125156489,-4.15581182,-1460.7210591118783 -1012,1012,A77H,0.071173928,-0.007256348,-0.000492809,0.014397303,-0.045084475,-0.014020655,0.056911065999999996,0.08543679,-0.209614293,-0.035441554,0.020928858999999998,-0.10610284800000001,0.10511723,-0.08401565,0.112810256,-0.056471405,-0.033697545,1.431794363,2.4714841080000003,-8.047659973,-6.917164146,-11.26828677,-8.624624062,-5.843152016,-7.585072867999999,-4.435187592,-4.108565032,-1461.4186592847109 -1013,1013,A77K,0.049965434,-0.050122967000000004,-0.0031809720000000002,-0.013919141999999999,-0.10161699699999999,0.008047406,0.030146283,0.06978458400000001,-0.27733533,-0.08890851599999999,-0.011337416999999999,-0.07764713200000001,0.071285189,-0.12933952099999999,0.10150123800000001,-0.11585035699999999,-0.087383636,1.36111989,2.194949085,-6.539634907999999,-4.241741005,-7.739748337000001,-8.565202744,-5.930411247,-6.221071205,-3.98182045,-3.451015588,-1456.1011032266542 -1014,1014,A77M,0.013687251000000001,0.00436159,0.031667438,0.024997295,0.00367316,-0.03223846,-0.026222898999999997,0.0535974,-0.18535465899999998,0.11562127,-0.106898091,0.015345945,0.047988931,0.016981068000000002,0.033013522000000003,0.055367673,-0.048021352999999996,1.242435059,2.981332762,-7.167273814,-4.589065338,-8.378811325,-9.604229355,-6.893565315,-6.370697739,-5.0985153,-3.8020842989999997,-1460.6895459899679 -1015,1015,A77L,0.031469627,-0.017614538,0.016396292,-0.003183666,-0.05205512,-0.051001332,0.009771245,0.053168007999999996,-0.183521963,-0.016131936,-0.01909714,-0.055406156,0.088198739,-0.048412352,0.042045020999999995,-0.07832668799999999,-0.025783552,1.320269367,2.2901041419999997,-6.9304190839999995,-4.667390900000001,-8.719584595,-8.201834305,-6.861184631,-6.20210099,-3.234713777,-2.70753155,-1459.1636531599797 -1016,1016,A77N,0.030823456000000003,-0.04101871,0.015666112,-0.014621358999999999,-0.102364519,-0.022762532000000002,0.027109297,0.034537614,-0.21387982,-0.056366389,-0.025671031,-0.045303428,0.076635652,-0.017127761000000002,-0.012114956000000001,-0.124007669,-0.080721368,1.203668451,2.104324851,-7.608313084,-7.327210547999999,-9.30059819,-8.129589935,-5.8258091510000005,-7.458357597000001,-4.79708571,-4.378504849,-1456.4286884735338 -1017,1017,A77Q,0.006138258000000001,-0.058917172000000004,-0.029064326,-0.052379304,-0.053635759000000005,-0.031816009,0.004151226,0.008125289,-0.241261791,-0.044126279000000004,-0.073708065,-0.10435439999999999,0.046225748,-0.08536679400000001,-0.019391814,-0.102259575,-0.005011942,1.304313342,2.205744571,-6.975806459,-4.619848129,-7.561933342000001,-8.821864417999999,-6.462393745,-7.4129926610000005,-4.803229085,-3.246582107,-1461.7685746927746 -1018,1018,A77P,0.0041314509999999995,-0.284897205,-1.557641204,-2.1699076440000002,-2.5264617,0.00471968,0.010424912,-0.00216201,-0.108881659,-0.164171972,-0.405622438,-1.593847281,-1.521435127,-1.9828172480000001,-2.35699804,-2.181949811,-2.870973588,3.766617301,2.09751268,-10.65186323,-9.572050697,-11.42293325,-11.79851699,-10.08500626,-10.38080894,-8.705427632000001,-9.614531994,-1463.8925999999046 -1019,1019,A77S,0.035106804,0.013368553,0.03985466,0.016302597,-0.106346494,0.011849931000000001,-0.012605698,0.082819306,-0.241940513,0.031791303,-0.005054197,-0.01579498,0.095504299,0.000641256,0.031963938,-0.07266742799999999,-0.14002556,1.181659527,2.2376350080000003,-5.185596034,-5.086449554,-5.699865585,-5.931232627999999,-4.6501632310000005,-4.560269173,-3.635938546,-3.443494686,-1462.3512315265834 -1020,1020,A77R,0.025660961,-0.021739187000000004,-0.007012498000000001,-0.018575674,-0.388606684,0.019988571,0.010319694,0.041002227999999995,-0.210810145,-0.014066538,-0.029411836,-0.078259663,0.064234668,-0.08577065800000001,0.048619311,-0.307798274,-0.46941509299999995,1.753896115,2.2199075930000003,-8.118550456,-5.531459717000001,-10.818280699999999,-10.05234763,-6.265542084,-7.925122153999999,-4.443004864,-3.4011665580000003,-1456.4235526192933 -1021,1021,A77T,0.009135381,-0.011429865,0.00021455,-0.038796865,-0.233979562,0.068669667,0.003588596,0.014682165,-0.204119983,0.038977861,-0.06183759,-0.037889701,0.03831880000000001,-0.07170419,-0.005889539,-0.177013485,-0.290945638,1.419586028,2.150478767,-4.972706778,-3.4807188489999996,-4.79836515,-6.730765915,-4.34101107,-5.512672905,-4.687920605,-1.884930054,-1462.3532720585354 -1022,1022,A77W,-0.010037885,-0.022470443,0.006612425,-0.025782612000000003,-1.6479342469999998,0.050072347999999996,-0.00012971600000000002,-0.019946053999999998,-0.241284109,0.028475421,-0.073416306,-0.056452132,0.069676982,-0.070629683,0.019064459,-1.5733002059999999,-1.7225682869999999,0.63772385,1.31531363,-11.41652313,-10.15662836,-13.12126321,-12.40772763,-10.63035065,-10.76664582,-5.9277859920000004,-5.807111517999999,-1472.3870512670837 -1023,1023,A77V,0.006094166999999999,-0.003418942,0.011197465,-0.005472483,-0.046064699,-0.034080658,-0.029416143999999998,0.041604478,-0.242265053,0.011493496,-0.018331379,-0.031502744,0.053897673,-0.038540103,0.027595137999999998,-0.058241832,-0.033887565,1.358902165,2.418300926,-5.388092123,-4.095331833,-5.560470581000001,-7.212319648999999,-5.335764526,-4.736574028,-3.448575308,-2.7049541219999997,-1465.428658229299 -1024,1024,A77Y,-0.001738225,0.008319888000000001,-0.003515975,0.00039913,-0.015251162,-0.045957843,-0.058565023,0.055088572999999995,-0.258101795,0.057562292,-0.040922517,-0.021157086000000002,0.014125136000000002,0.012656703,-0.011858443,0.041536724,-0.072039047,1.190884922,2.819835845,-10.13204072,-8.911687645,-13.10412857,-11.08639387,-8.902134605,-8.655858894,-5.125928953,-3.5374393580000003,-1466.1991274389438 -1025,1025,V78A,-0.027555502000000003,0.028317385,-0.03081787,-0.027847157999999997,-1.656196595,0.054383624000000005,0.004113835,-0.059224837999999995,-0.004426986,0.034597035,0.022037735,-0.020579704,-0.041056035,-0.008189373,-0.047504942,-1.4305480259999999,-1.8818451630000002,0.857223423,1.337815564,-4.062076318,-4.202271973,-3.100818359,-5.820414177000001,-3.4625128860000003,-3.724364197,-3.7119873080000003,-1.333522514,-1453.9430578141473 -1026,1026,V78C,0.026739392,0.036746746000000004,0.019432161,-0.18533655100000002,-1.68324771,0.09669272400000001,0.033276344,0.020202439,-0.009745623,0.08511134,-0.011617849,0.007092815,0.031771507000000004,-0.08811702800000001,-0.282556074,-1.5363938209999999,-1.8301015980000002,0.793518574,1.3246090940000002,-8.693039894,-7.206258438,-6.377994087,-12.60800379,-9.155328796000001,-8.117614357,-5.841966481,-4.404980384,-1466.0868462799117 -1027,1027,V78E,0.057113482,0.036711092,-0.10133983199999999,-1.556595863,-2.698340925,0.025070162000000003,0.064694858,0.049532106,0.009347684,0.034849078,0.038573105,-0.056752440999999994,-0.145927223,-1.496376054,-1.616815671,-2.603828308,-2.7928535410000004,0.778186905,0.710328044,-10.532427900000002,-10.24104378,-8.616250893,-13.796377,-9.903016609,-10.10545122,-8.519744082,-7.302159776,-1457.6176766669378 -1028,1028,V78D,0.020108278,-0.539073526,-1.898579971,-2.677275235,-2.787729305,0.011166081000000001,0.043481415,-0.00326486,0.08870515,-0.27724747,-0.800899582,-1.474267269,-2.322892672,-2.42700979,-2.927540679,-2.493069359,-3.08238925,1.242355429,0.108476669,-11.68439271,-11.5038268,-9.476012062,-15.49437652,-11.130044300000002,-10.81770385,-9.404967002000001,-9.769835496,-1464.0180396283977 -1029,1029,V78G,-0.027763323,-0.046947496,-1.31711,-2.105566334,-3.18578003,0.083098031,-0.004739427,-0.050787217999999995,0.02351664,0.010964568999999999,-0.10485956,-1.2233401590000001,-1.4108798409999999,-2.1180907330000003,-2.093041934,-3.1383928119999998,-3.233167248,0.8910931559999999,0.11161704199999999,-9.755791618,-9.511101875,-7.396039032000001,-13.43148764,-9.277208099,-9.163121445,-6.645698291,-3.9181378760000003,-1463.7409860654734 -1030,1030,V78F,-0.025469275,-0.022839962999999998,-0.050249756,-0.880751637,-2.180567854,0.019111483999999998,-0.029308288,-0.021630261,0.072448266,0.013446943000000001,-0.059126869000000006,-0.065957977,-0.034541535,-0.476853914,-1.28464936,-1.9298581069999998,-2.4312776,1.503619779,1.345472145,-8.935931407,-7.664467865,-6.0858837889999995,-13.64936545,-10.99159146,-6.288348472999999,-5.128154225,-1.7804540819999999,-1454.7707138839178 -1031,1031,V78I,-0.062067489,0.016499933,0.051312049000000005,-0.003313895,0.00016968400000000002,-0.012927375,-0.100050322,-0.024084655,-0.10381161800000001,0.097941599,-0.064941734,0.109716569,-0.007092472,0.069588418,-0.076216208,0.10772554,-0.10738617199999999,1.080855097,3.0984630010000003,-1.321723781,-1.0785215,-0.861712845,-1.9342504580000002,-1.704240578,-1.029893524,-2.40347452,-1.458571152,-1459.1066289809532 -1032,1032,V78H,-0.016270898,0.010942452,0.028227537,-1.395238734,-2.543009613,0.028662818,0.00107947,-0.033621265,0.01578637,0.126303282,-0.104418378,0.09684216,-0.040387086,-1.133449261,-1.657028207,-2.177232435,-2.9087867910000003,0.916804627,0.76543097,-13.10812769,-11.4709725,-10.43869939,-18.63355664,-13.11593847,-11.88147144,-9.404967002000001,-9.769835496,-1461.5547056067735 -1033,1033,V78K,0.0018391179999999998,-0.040107999,-1.266341998,-1.86552629,-2.59120482,0.035098778,0.042531337,-0.038853101,0.066450097,0.034246193,-0.11446219,-1.242360167,-1.290323828,-1.9204016309999998,-1.810650949,-2.287491195,-2.894918445,3.081158498,1.624375066,-11.34127313,-10.80767766,-8.72908091,-14.58131466,-10.94871952,-11.63957289,-9.404967002000001,-9.769835496,-1463.0343988928944 -1034,1034,V78M,-0.061921223,0.0024918,-0.035672751,-0.051007132999999996,-0.582851742,-0.044427402000000005,-0.074949591,-0.048892855,0.02369312,0.063219975,-0.058236376,-0.00238476,-0.068960742,-0.029490996000000002,-0.072523269,-0.388598315,-0.777105168,1.325946355,1.813477872,-5.577692776,-3.782774368,-3.86007341,-8.493511444,-5.767599442000001,-5.984505219,-4.561860221,-2.828694156,-1455.1156407683156 -1035,1035,V78L,0.010158283,0.039151264,-0.014894886999999999,-0.010168567,-0.34449891,-0.017061268,0.015847088,0.004469477,0.03760816,0.056109612,0.022192916,-0.005619712,-0.024170061,-0.00663738,-0.013699753,-0.244243085,-0.444754735,1.120110615,1.819710138,-3.771456212,-2.371703178,-1.886697784,-6.049359871,-4.538904533,-4.010615692,-2.25114419,-0.698352594,-1455.1503106029704 -1036,1036,V78N,0.109613889,0.10699724099999999,-0.7763474779999999,-2.041028381,-2.753542442,0.11098701,0.134712585,0.08451519199999999,0.037409082999999996,0.081191342,0.13280314,-0.719264977,-0.833429979,-1.519040039,-2.563016722,-2.488189594,-3.0188952889999996,2.245832708,1.1785706470000001,-10.83381969,-9.959333588,-9.126215126,-14.98013526,-10.47648077,-9.626933722999999,-8.570608566,-7.304091845,-1465.7701604911126 -1037,1037,V78Q,-0.004544015,0.06450285900000001,-0.090802632,-1.611977588,-2.523461653,0.087838506,0.034859493,-0.043947522999999995,-0.051435077,0.099517596,0.029488121000000003,-0.088363842,-0.09324142199999999,-1.4787908790000002,-1.745164296,-2.146910439,-2.900012867,2.444705609,1.527175785,-11.20310578,-10.55054248,-9.018334068,-14.27371986,-10.66071827,-11.51221422,-9.404967002000001,-9.769835496,-1460.3988361861557 -1038,1038,V78P,0.007812375999999999,-1.3839294180000001,-2.338744619,-2.553140845,-3.162109295,0.041470082000000005,0.013359995,0.002264756,-0.051943431,-1.420364231,-1.347494605,-2.255159574,-2.4223296640000003,-2.202149766,-2.904131923,-2.944902945,-3.379315645,0.164255557,-0.9114215509999999,-11.28568029,-10.96703996,-9.456898597999999,-14.24493577,-11.223206300000001,-10.53632084,-9.18009789,-8.885780033,-1466.5039132549427 -1039,1039,V78S,5.6999999999999996e-05,-0.01492458,-0.029728687,-1.5818225069999998,-2.7418226160000003,0.05588670900000001,0.032656862,-0.032542877000000005,0.060577734,0.000567411,-0.03041657,-0.049098695,-0.010358678,-1.451837586,-1.7118074269999999,-2.5459258780000003,-2.937719354,0.802916582,0.7161327359999999,-8.805281395,-8.415005096,-7.566246788,-12.84734567,-8.017875366,-7.179934059,-7.159195795,-5.310112065,-1459.5131406020373 -1040,1040,V78R,-0.016696638,-0.8817764659999999,-2.15087015,-2.720000761,-3.102488852,0.07550873599999999,0.013823101,-0.047216376,-0.026863254,-0.781738697,-0.981814234,-2.0781431280000002,-2.223597172,-2.18578761,-3.2542139110000003,-2.4948852269999997,-3.710092477,1.163432303,-0.380500606,-11.77599404,-11.200096,-9.295713226,-14.83683981,-11.28011063,-12.26721054,-9.404967002000001,-9.769835496,-1460.922570841387 -1041,1041,V78T,-0.047361462,-0.013638888,-0.036233974,-0.017847592,-1.133446022,0.085036623,-0.019340307,-0.075382617,-0.025164889,0.06496667099999999,-0.092244446,-0.010690881000000001,-0.061777067000000005,0.016883013,-0.052578195999999994,-0.8273278059999999,-1.4395642380000002,0.6926381220000001,1.3730777790000002,-4.782004752,-4.64653241,-3.81305806,-6.092572174,-4.074017715,-5.283843398999999,-4.947254074,-2.4570170669999998,-1460.969159675762 -1042,1042,V78W,-0.015194464,-0.006698435,-0.188115187,-1.626287272,-3.018125613,0.016416326000000002,-0.007709725,-0.022679202000000002,-0.007536352,0.000493439,-0.013890308999999998,-0.185521987,-0.190708386,-1.543628536,-1.708946007,-3.072086102,-2.964165123,1.068385064,0.7331822790000001,-10.98333531,-9.522569191,-8.576773697,-14.5115048,-12.81020496,-9.495623878,-7.5532061310000005,-5.550567107000001,-1465.8594737402163 -1043,1043,V78Y,-0.011703516,-0.001238355,-0.140580622,-1.732783391,-3.0241013789999998,-0.005414191,0.032659972999999995,-0.056067004000000004,0.055128393,-0.008961695,0.006484985,-0.17904832,-0.10211292300000001,-1.48081484,-1.984751942,-2.908602245,-3.139600513,1.1831139529999999,0.760283116,-10.58229114,-9.315712074,-7.937860328999999,-15.48936933,-12.09290049,-8.075613487,-6.379704826,-3.329321517,-1458.6300911181606 -1044,1044,L79A,-0.027199496,0.020965509,-0.00032943699999999997,-1.4004483230000002,-2.179578454,0.052610227999999995,-0.025240415,-0.029158577,-0.140901066,0.026562281,0.015368737,3.84e-05,-0.0006972739999999999,-1.18187343,-1.619023216,-2.117712719,-2.241444188,0.7793568679999999,0.735947185,-11.44791021,-11.79618906,-8.965540764,-10.03492208,-11.18583176,-15.25706737,-7.4516374679999995,-2.8302191889999997,-1452.5724258678965 -1045,1045,L79C,-0.052613768,0.020461453,0.02222396,-1.3800633080000002,-2.26771596,0.091646041,-0.020622069,-0.08460546599999999,0.118005724,0.017321625,0.02360128,0.038542863,0.005905056999999999,-1.068190641,-1.691935975,-2.109224609,-2.42620731,2.142608125,1.463108565,-11.53625072,-9.723113419,-10.25314166,-11.93094589,-12.21417496,-13.55987766,-7.5166219110000005,-3.5646175189999996,-1461.1465914850123 -1046,1046,L79E,-0.024628399,0.002605446,-0.999195278,-1.8881364880000002,-3.1290289419999997,0.021471003,-0.021610083999999998,-0.027646713,0.144334663,0.03382983,-0.028618937999999997,-0.933556718,-1.064833838,-1.7669701230000001,-2.0093028530000003,-2.8277481489999996,-3.430309735,2.2508329590000002,1.037657499,-13.09266496,-11.97408675,-11.3318261,-12.04619616,-13.45608823,-16.65512756,-8.190376404,-5.159379883,-1461.4171560802497 -1047,1047,L79D,-0.01514938,-1.096653208,-1.993373786,-3.157187585,-3.0608791319999997,0.026019672999999997,-0.015715118,-0.014583641000000001,0.17236338699999998,-1.074835993,-1.1184704220000001,-2.023147651,-1.96359992,-2.90002675,-3.414348419,-2.529441012,-3.592317252,0.054865335,-0.6803795659999999,-16.64588079,-16.71652667,-15.288191199999998,-15.60343378,-16.19079913,-19.43045316,-10.88598105,-10.08874765,-1465.6278719906695 -1048,1048,L79G,-0.028099122999999997,-0.019732318999999998,-1.070240267,-2.059000909,-2.957194765,0.054761721,-0.012649117,-0.043549128,0.03239566,-0.000253641,-0.039210997000000004,-1.023416898,-1.117063636,-1.785576425,-2.3324253930000003,-2.591081946,-3.323307583,2.462287334,1.159028495,-14.18183921,-13.76888288,-11.84847445,-13.88775539,-14.25061777,-17.15346558,-8.597913307999999,-5.714715274,-1470.5222977478988 -1049,1049,L79F,-0.01025245,0.012232916000000002,-0.029724262999999997,-1.093196663,-1.8680204669999998,0.033997307000000004,0.008388181,-0.028893081,0.037664813,0.010527574,0.013938256999999999,-0.044932282000000004,-0.014516244,-0.8313834959999999,-1.355009829,-1.7160702630000002,-2.019970671,2.504333843,1.9005230430000002,-8.465023422,-10.94694992,-6.956252144,-7.58403598,-8.726030571,-8.111848495,-6.441491471,-1.5360712909999998,-1454.1851739995182 -1050,1050,L79I,-0.07409731,0.005641340999999999,-0.032207669,-0.280652553,-1.992318096,0.044192605,-0.07711256400000001,-0.07108205599999999,-0.149855908,0.038759872,-0.02747719,0.011413885,-0.075829222,-0.13421424099999998,-0.427090865,-1.8268367230000002,-2.157799469,1.0396290190000002,1.322823716,-8.73838091,-9.859851044,-7.685239365,-8.519657509,-8.507558701,-9.119597931,-7.26152844,-4.890526914,-1453.0920499605127 -1051,1051,L79H,0.000578543,-0.048363297,-1.366124024,-2.62410068,-2.3376866069999997,0.034573267000000005,0.011400516000000001,-0.010243430999999999,0.26927340000000005,0.002596363,-0.09932295699999999,-1.1604122270000001,-1.5718358209999999,-2.0117372209999997,-3.2364641389999997,-2.516212746,-2.159160468,2.29428051,0.925031866,-14.11064839,-13.81050754,-11.77828395,-13.10009328,-13.463413500000001,-18.40094366,-8.004145637999999,-4.189848298999999,-1463.2870134785771 -1052,1052,L79K,-0.027209036000000002,-0.8994973829999999,-2.7488818989999997,-2.66842034,-2.660157517,0.07041505299999999,-0.06577263900000001,0.011354567,0.427635892,-0.8676425809999999,-0.9313521840000001,-2.543412781,-2.954351017,-2.2741638440000003,-3.062676835,-2.380699361,-2.939615673,-0.35623305200000005,-0.6350221420000001,-15.0862654,-15.2202095,-13.30032058,-13.88620414,-13.989713,-19.03487977,-9.985118026,-7.7141849979999995,-1466.9926051627845 -1053,1053,L79M,-0.041127222000000005,-7.92e-05,0.011891843000000001,0.017498071,-0.13668174800000002,0.062130882000000005,-0.028895415,-0.053359027999999996,-0.212987495,0.009610322,-0.009768671,0.048429590999999994,-0.024645906000000002,0.03058431,0.004411832,-0.064670196,-0.2086933,1.2791909540000002,2.3987463559999997,-6.232096787000001,-7.994527107000001,-5.208280418,-5.136859695,-6.139987564,-6.680829147000001,-5.200660259,-2.5376454230000003,-1452.6287754056975 -1054,1054,L79N,-0.04360167400000001,0.052140272,-0.723643987,-2.0327400669999998,-2.6521134969999998,0.15569389,-0.009523327,-0.077680021,0.239310176,0.022842391,0.081438153,-0.6986852990000001,-0.748602674,-2.248980298,-1.816499835,-2.355515815,-2.948711178,1.60942797,0.6144988220000001,-14.60604326,-15.12296925,-12.10307977,-14.43522932,-14.18582407,-17.18311392,-8.929622169,-6.37161525,-1467.9864445114508 -1055,1055,L79Q,0.029095556,-0.006962171999999999,-0.057202848,-1.464256965,-2.306304801,0.049686827999999995,0.032523022,0.02566809,0.20039211,-0.034112999,0.020188656,-0.08149426900000001,-0.032911427,-1.544639092,-1.383874838,-2.404502275,-2.208107326,0.8509257840000001,0.712602269,-12.89702171,-12.73980621,-10.67189474,-11.81076484,-11.49293997,-17.76970277,-8.532294561,-6.160538967999999,-1463.5716805122793 -1056,1056,L79P,-0.041661111,-1.422050147,-2.334715798,-2.613714355,-3.139544463,0.065740545,-0.036098862999999995,-0.047223359000000006,0.015535506000000001,-1.4739031130000002,-1.370197181,-2.195430804,-2.474000792,-2.201404599,-3.02602411,-2.6437322169999997,-3.635356708,-0.187841378,-0.923340347,-15.212355800000003,-15.86277149,-13.32132626,-14.41690884,-14.90249727,-17.55827515,-10.88152322,-10.06790871,-1466.609342941083 -1057,1057,L79S,-0.034683821000000004,-0.026581004,-0.329449314,-1.670463279,-2.5468891190000003,0.083495357,-0.023753396,-0.045614245,0.086177239,-0.017654719,-0.035507289,-0.23302044600000002,-0.42587818200000005,-1.401052184,-1.939874374,-2.23998146,-2.853796778,2.408364335,1.4706181630000001,-13.93018694,-14.21009344,-11.30063876,-14.0202532,-14.11391738,-16.00603193,-8.822694092999999,-6.255023102000001,-1459.8034395654686 -1058,1058,L79R,-0.025002387,-0.6300707720000001,-2.07486141,-2.640855904,-2.817926043,0.085764392,-0.012735762,-0.037269012000000004,0.18660382600000003,-0.559063235,-0.701078309,-2.210009851,-1.9397129690000001,-2.287548401,-2.994163406,-3.0472964310000004,-2.588555654,0.337410538,-0.510504784,-14.91602951,-15.413437099999998,-12.60615955,-13.20636533,-13.14023171,-20.21395383,-9.344230412,-6.655404396000001,-1465.2845694092102 -1059,1059,L79T,0.015913008,0.00022276299999999998,-0.463125385,-1.7603153459999998,-2.2124619,0.066973833,0.017578826000000002,0.01424719,0.36424891299999995,-0.03315881,0.033604336,-0.36843225,-0.55781852,-1.4416059940000001,-2.079024697,-2.042991532,-2.381932267,3.050034408,2.029006614,-12.1605653,-12.09567677,-10.89824052,-11.17848842,-12.35365549,-14.27676527,-7.929140714,-5.677033493,-1460.9132883828133 -1060,1060,L79W,-0.060461617999999995,-0.5559709820000001,-1.952050308,-2.538815624,-2.385535496,0.03155105,-0.044539752,-0.076383484,0.14017870300000002,-0.43340531,-0.678536653,-1.925785012,-1.9783156030000002,-2.434687326,-2.642943921,-2.3651315840000002,-2.405939407,1.2665556690000002,-0.068952325,-12.43776017,-13.86545841,-10.26577203,-11.42909258,-12.05515448,-14.57332337,-8.433482967,-6.189235158,-1463.9157605669461 -1061,1061,L79V,-0.045812026,0.014359393,-0.0020797339999999997,-0.039006771,-1.786521316,0.067834647,-0.038276681,-0.05334737,0.001473321,0.019365586,0.009353199,0.011073528000000001,-0.015232996,0.010527672,-0.08854121400000001,-1.64900771,-1.9240349209999998,0.576076295,1.307886431,-8.534597427000001,-8.64973278,-7.34083844,-8.09098098,-8.092796036000001,-10.498638900000001,-6.740706465,-4.545376001,-1456.260180927813 -1062,1062,L79Y,-0.036318317,0.00616585,-0.431122374,-1.720367866,-3.023729688,0.048682853,-0.017739712,-0.054896922,0.31503089,0.022461263999999998,-0.010129565,-0.280711953,-0.581532794,-1.4586210480000001,-1.9821146840000001,-2.7112846,-3.3361747760000005,1.370118714,0.802306306,-12.49143999,-14.73701756,-10.55982866,-11.02231803,-11.60971087,-14.52832485,-8.090072069,-2.041093615,-1456.3362538926303 -1063,1063,S80A,0.003780435,-0.000112187,-0.023835066000000002,-0.039978282000000004,0.008730478,-0.045163348,-0.005619985,0.013180853999999999,0.009412882,0.027437279,-0.027661652999999998,-0.007235320999999999,-0.040434811,-0.016718541,-0.063238022,0.013631965,0.00382899,1.129499537,2.631264114,0.658957611,0.035413863999999996,1.065093132,1.090233009,0.0018784479999999998,1.102169601,-1.3739425440000002,1.049533607,-1465.2908440097235 -1064,1064,S80C,-0.019945796000000002,-0.005649763,0.022313335,-0.003480105,-1.017420265,0.025241577999999997,-0.043087944,0.003196352,-0.000424303,0.0068516259999999996,-0.018151152,0.037051623,0.007575045999999999,0.018116052,-0.025076262000000002,-0.706796778,-1.328043751,0.6774278009999999,1.388823255,-6.109152402,-5.983003471,-7.553816521,-5.99990728,-5.361860291,-5.647174446,-6.9900029120000005,-2.7476411069999997,-1463.8554959651083 -1065,1065,S80E,0.065645263,0.13345243099999998,0.070824647,0.0431435,0.100922601,0.041882749,0.07877806,0.052512465,0.010391963,0.120139854,0.146765007,0.044151964,0.09749733,-0.065543575,0.151830574,0.025852224,0.175992978,1.2051106459999998,2.659023445,-3.6246211460000004,-2.346104378,-4.472059776,-4.61055278,-2.958171516,-3.7362172780000003,-4.341704233,0.48522707299999995,-1453.291973582469 -1066,1066,S80D,0.052241377,0.036279143,0.049174175,-0.017654791,-0.21707091899999997,-0.023723154,0.056517915999999994,0.047964837,-0.078792483,0.071720084,0.000838202,0.085544649,0.012803701,0.088448043,-0.123757625,-0.11083853,-0.323303307,1.349599622,2.3388948569999997,-2.988735117,-1.723924599,-3.115274437,-3.9605267110000004,-2.944482101,-3.199467735,-4.51670741,0.864028315,-1450.4672392802313 -1067,1067,S80G,0.007324998,0.027652312000000002,0.020959051,-0.026581208999999998,-0.060435341,-0.044996303,-0.01862526,0.033275256,-0.01419731,0.068639222,-0.013334598999999999,0.015954886,0.025963216,0.0016657420000000002,-0.054828159,-0.005475071,-0.115395611,1.305254706,2.680820742,-5.03810191,-4.347550818999999,-6.180046425,-4.998769753,-4.2878851010000005,-5.376257454,-5.572651789,-2.11475684,-1464.9429927472956 -1068,1068,S80F,-0.021936472000000002,0.049727858,-0.013782935,0.015995894,-0.022349997000000003,-0.046772022999999996,-0.040762226,-0.0031107170000000003,-0.034577581,0.08814697199999999,0.011308743000000001,0.043813200999999996,-0.07137907,0.020868631999999998,0.011123155,-0.016487452,-0.028212541,1.3246820540000002,2.628936646,-6.360696454,-6.457349205,-8.382338104,-6.219138152999999,-4.836637421,-5.908019386,-6.812746309,-3.5348249480000002,-1465.070305994479 -1069,1069,S80I,0.058598247,0.010656671000000001,0.036695347999999996,-0.019389035,-0.25249564,-0.121116769,0.048564033,0.06863246099999999,-0.09565490900000001,0.068755605,-0.047442263,0.07526501,-0.001874315,-0.005783563,-0.032994506,-0.216255127,-0.288736153,1.42893757,2.13258098,-6.298324435,-5.641306107,-6.815551735,-6.233091034,-5.528832367000001,-7.272840935,-7.397706917000001,-3.3897317680000003,-1465.65692610736 -1070,1070,S80H,-0.004397067,0.072688406,0.035928497000000004,0.01723173,0.034713463,-0.000986392,0.020030608999999998,-0.028824742,0.027715976,0.168619086,-0.023242274,0.110018418,-0.038161424,0.058938089000000006,-0.02447463,0.11218065,-0.04275372400000001,1.07739216,2.92220415,-3.20298566,-1.987098755,-6.339782477999999,-3.4761483610000004,-0.959738808,-3.252159897,-4.3745817360000006,0.382901216,-1457.8411954077892 -1071,1071,S80K,-0.057452679000000006,-0.044111019,-0.164630083,-0.153568991,-0.065342318,-0.07902754099999999,-0.100079365,-0.014825993,0.17202957600000002,0.129712031,-0.217934068,-0.12626216199999998,-0.202998003,-0.104070105,-0.203067876,0.018755069,-0.149439705,1.287897993,2.596848787,-3.330130141,-2.146525284,-5.587464272,-4.032521255,-2.288232735,-2.595907158,-3.189259936,0.695284114,-1458.3811649410054 -1072,1072,S80M,-0.023645486,0.028413589,-0.010094269,0.003971601,-0.066786124,0.009913543,-0.098890094,0.051599122000000004,0.017987373,0.056283112999999996,0.000544065,0.034392127,-0.054580665,-0.015418477,0.023361677999999997,-0.035650611,-0.09792163699999999,1.3232182270000001,2.490043386,-5.324362936,-4.538106705,-5.782431435,-6.135371407,-4.882769035,-5.283136101,-5.615595014,-2.340792165,-1462.3139017987996 -1073,1073,S80L,-0.033878732,0.0032334829999999997,-0.00977208,-0.021265886,-0.017216283,-0.080803054,-0.052288021,-0.015469442,-0.035084031,0.08743781800000001,-0.080970852,0.046162345,-0.065706504,0.038515577,-0.08104734799999999,0.022042954,-0.05647552,1.203945648,2.756117793,-4.338200618,-3.712005524,-4.7932325669999996,-4.782631912,-4.116888855,-4.286244232,-5.262522874,-1.358235053,-1455.6927341273986 -1074,1074,S80N,-0.08671345,0.049912539000000006,0.025657988,0.012276138999999998,0.037980215,-0.023101176,-0.10380426300000001,-0.069622637,0.030572227999999996,0.14624426599999998,-0.046419189000000007,0.15933086300000002,-0.108014888,0.166695654,-0.142143377,0.099507291,-0.023546861000000002,1.068522011,2.96610325,-3.769201868,-2.951911552,-5.535278937999999,-4.531556114,-2.620296471,-3.206966263,-4.313887581,-0.324222475,-1459.636347109452 -1075,1075,S80Q,0.020450486,0.078464841,0.047844936,0.051442337000000005,0.04227319400000001,0.0051349690000000005,-0.012027286000000002,0.052928257,-0.029723674,0.129502378,0.027427304,0.119402916,-0.023713045,0.087036203,0.015848471,0.104629267,-0.020082878999999998,1.0730225290000002,3.070684425,-3.529826997,-1.764112625,-6.569729691,-4.41730645,-1.632978477,-3.2650077439999996,-3.38666574,0.905837643,-1456.8849792168476 -1076,1076,S80P,-0.021013734,-0.22632506,-1.477347225,-1.9530013659999998,-2.293021701,-0.012783471000000001,-0.014290457,-0.02773701,-0.017278796000000003,-0.106669068,-0.345981052,-1.3603607290000002,-1.594333721,-1.68340233,-2.222600401,-1.842583915,-2.743459487,4.116280145,2.689273208,-7.774037581,-7.403420418,-8.542975616,-8.064102843999999,-7.209498572999999,-7.650190453,-9.046659553,-7.18566065,-1455.5473787877709 -1077,1077,S80R,0.043912014000000006,0.023830552999999997,0.02109135,-0.00687618,0.006316881999999999,-0.072262985,0.045482996,0.042341032,0.01229648,0.04771220599999999,-5.11e-05,0.037250681,0.004932019,0.019911584,-0.033663942999999995,0.034362348,-0.021728584,1.216313162,2.80333895,-4.294402144,-3.115541458,-7.105670227,-4.96301696,-2.309520744,-3.97826133,-3.0527667060000003,1.5245579340000002,-1455.5924772243015 -1078,1078,S80T,-0.021110906000000002,-0.041997509,-0.009250742,-0.024874772000000003,-0.022612891,-0.067392295,-0.018287051999999998,-0.023934759,-0.012708157,-0.003439288,-0.080555729,-0.010567761,-0.007933723,0.005606262,-0.055355805,0.00065279,-0.045878572,1.163320143,2.5198995109999998,-2.525990964,-2.48811644,-2.7397015610000004,-2.717346558,-2.192399834,-2.4923904269999997,-4.321798547,-1.148135986,-1463.8163986108266 -1079,1079,S80W,-0.005498158,0.074824648,0.00672506,0.043488848,0.012556073999999999,-0.13566019199999999,-0.05538797,0.044391655,-0.093928877,0.160226389,-0.010577093000000001,0.055581425999999996,-0.04213130599999999,0.11683221099999999,-0.029854516,0.105383003,-0.080270855,1.079411031,2.92183514,-6.828069016000001,-6.330684547000001,-7.726988785,-7.298850975,-5.2123834460000005,-7.571437325,-6.522338432000001,-2.791895324,-1467.4526083944365 -1080,1080,S80V,-0.008756696999999999,0.001130836,-0.021038003,-0.053764297999999995,-0.081587569,-0.100935845,0.009251823000000001,-0.026765216,-0.054204858,0.040672519,-0.038410848,-0.016725951,-0.025350054,-0.009834755,-0.09769384099999999,-0.022315281,-0.140859856,1.19428499,2.477242401,-3.78905907,-3.4845488889999996,-3.9785698089999997,-3.989531593,-3.511034958,-3.9816101,-4.766424209,-1.871814991,-1467.0609622779302 -1081,1081,S80Y,0.038575432,0.046273308,0.006748659000000001,-0.029824102,0.040013894,-0.08489228,0.003971494,0.07317936900000001,0.04097022,0.056007457999999996,0.036539157,-0.00119747,0.014694786999999999,-0.05283594,-0.006812264,0.0017441029999999999,0.078283685,1.198251489,2.6299958880000003,-5.023483173,-4.383644653,-8.256493637,-5.101976379,-2.106969383,-5.26833181,-5.262635241,-1.387936311,-1467.479451886844 -1082,1082,R81A,-0.017815333,-0.01776894,-0.037088676,-0.021613384,-0.188147805,0.009769238000000001,-0.06681864400000001,0.031187977999999998,-0.039554076,-0.0015434429999999998,-0.033994436,-0.023585909,-0.050591443,-0.034647541000000004,-0.008579226,-0.18541005800000002,-0.19088555100000001,1.621299332,2.325708276,-6.800035385,-5.662657303,-6.267086578,-7.778174507,-7.584325661,-6.707932877,-5.924910882000001,-0.9334941240000001,-1449.0483589060605 -1083,1083,R81C,-0.027420629,-0.004582591,-0.031563928,-0.371294341,-1.624129056,0.10201629699999999,0.001005894,-0.055847151,0.0163518,-0.016699436,0.007534255,-0.05452100000000001,-0.008606856,-0.22171987899999998,-0.5208688029999999,-1.690131812,-1.558126299,1.337254274,1.374435638,-9.70629068,-8.691199425,-10.29591684,-10.34909089,-9.532753937,-9.66249231,-7.304108984,-4.419697544,-1457.425951525569 -1084,1084,R81E,-0.018979202,-0.012774246999999999,-0.03799178,-0.015531669,-1.4667390530000002,0.068227587,-0.011197166000000001,-0.026761238,-0.034149317,-0.054504919000000006,0.028956425,-0.063556895,-0.012426665,-0.048918305999999995,0.017854968,-1.495404654,-1.4380734519999998,0.748324407,1.324960167,-6.38438447,-5.056917946,-7.0191589510000005,-6.903066657999999,-7.142991837,-5.799786957,-5.324598647,-0.923295405,-1449.443880834151 -1085,1085,R81D,3.77e-05,0.00793268,-0.03210496,-0.446090128,-1.5815176690000001,-0.035873802999999996,-0.010694901000000001,0.010770298999999999,-0.005869676999999999,-0.031195233,0.047060592000000005,-0.020556543,-0.043653377,-0.23871049600000002,-0.653469759,-1.737491345,-1.425543993,1.350288875,1.368310013,-6.6262499770000005,-4.281867355,-7.593464813,-5.950424011,-6.638147292999999,-8.667346412999999,-5.382875144,-1.1567101770000001,-1452.2892077979632 -1086,1086,R81G,-0.061778215,-0.028050445,-0.077628369,-0.043402497000000005,-1.513572123,0.006583006999999999,-0.08633876,-0.037217669,-0.021909968999999998,-0.035025985,-0.021074904,-0.069222768,-0.086033969,-0.045869372,-0.040935622000000005,-1.382198379,-1.644945867,0.8268371309999999,1.3389096740000002,-6.2304477810000005,-6.390813652,-6.592454575,-6.83187487,-6.007526642,-5.329569168,-5.579214821,-2.178875398,-1458.4297203761525 -1087,1087,R81F,0.059842322,0.068162342,0.025830263,0.001161222,-0.699796092,0.094903217,0.052666066,0.067018577,-0.09909509400000001,0.027263447000000003,0.10906123699999999,-0.004547025,0.056207550999999994,-0.053453357,0.05577580099999999,-0.573211047,-0.826381136,1.3592227780000001,1.6924534480000002,-11.70878268,-9.998816872,-11.7766423,-12.72111183,-10.320478199999998,-13.72686418,-7.837640966,-4.27556118,-1457.0871219271794 -1088,1088,R81I,-0.000672619,0.037720929,-0.046975253,-0.0584146,-1.42389794,0.027153487999999996,-0.026017684,0.024672446,-0.070179215,-0.023855211,0.099297068,-0.028326112,-0.065624393,-0.054696960999999995,-0.062132239000000006,-1.1653607129999999,-1.6824351659999999,0.888948216,1.366223025,-10.75231271,-10.46017023,-10.48652612,-12.96393156,-9.663714577,-10.18722108,-8.527733181,-5.707633559,-1457.216827149503 -1089,1089,R81H,-0.08531382800000001,-0.035217379,-0.101156614,-0.039854742,-0.321205933,0.001246909,-0.112464596,-0.05816306,-0.015215191999999999,-0.032504757999999995,-0.03793,-0.0455228,-0.15679042699999998,-0.018971915,-0.060737568,-0.185042156,-0.45736971,1.238500805,2.015814537,-6.045845535,-6.433644714,-6.127481461,-6.044689902999999,-5.746162781000001,-5.877248817000001,-6.431439571,-3.055176,-1453.2982128583826 -1090,1090,R81K,-0.043906191,-0.0666552,-0.052535839,-0.074443465,-0.051616290999999995,-0.048374096,-0.05829417,-0.029518212000000002,-0.044841455999999995,-0.07595604,-0.057354359,-0.043955435999999994,-0.061116242,-0.058836501,-0.090050429,-0.064151378,-0.039081204,1.334835492,2.373449504,-3.9808057339999996,-4.303813393,-4.020109375,-3.6353725889999997,-3.3626632689999996,-4.582070045,-4.312134604,-0.8245219540000001,-1462.566893817857 -1091,1091,R81M,-0.036461006000000004,-0.031057745,-0.058285708,-0.087047375,-0.186559753,0.002318691,-0.105449437,0.032527425,-0.11362440300000001,-0.014829525,-0.04728596400000001,-0.017651552,-0.09891986400000001,-0.072462026,-0.10163272300000001,-0.13698518199999998,-0.23613432399999998,1.345279514,2.160178499,-8.79054639,-8.778355522,-8.485091591,-11.23664427,-7.553442245,-7.899198318,-6.680057505,-2.620263835,-1451.0924832224846 -1092,1092,R81L,0.010610116000000001,0.008759646,-0.022884488999999997,-0.026334056,-0.179219629,-0.05354498,-0.006990693,0.028210924,-0.012710508999999998,-0.026509479,0.04402877,-0.035876592,-0.009892386,-0.039205909,-0.013462203,-0.16088729,-0.197551968,1.458192345,2.233501817,-6.114860832000001,-5.912994293,-6.153731232,-8.853515739,-4.909612686,-4.744450211,-5.038215288,-1.3788029380000002,-1454.3818905041553 -1093,1093,R81N,-0.014860759,-0.042889953,-0.051431365,-0.07123174,-0.23924434100000003,0.045580851,-0.043544014000000006,0.013822497,0.0077538880000000004,-0.06874627700000001,-0.017033628999999998,-0.08671964800000001,-0.016143081,-0.09111174699999999,-0.051351733,-0.269564337,-0.20892434399999998,1.54860694,2.093003216,-6.886143845,-6.066132339,-7.4382342,-6.6212352679999995,-6.693255035,-7.611862381,-5.65073081,-3.1703742010000004,-1455.5217943708412 -1094,1094,R81Q,-0.07544084200000001,-0.013630202,-0.041055384,-0.06362775700000001,-0.21571248399999998,0.014635173000000001,-0.12050081300000001,-0.030380871,-0.005751541999999999,-0.018338911,-0.008921492,-0.015756527,-0.066354241,-0.073571796,-0.053683718,-0.21074081,-0.22068415800000002,1.4980799930000002,2.163044811,-4.171325552,-4.1288100739999996,-4.421803307,-4.655102363999999,-4.47781218,-3.173099838,-4.897855894,-0.111195313,-1454.4354098727927 -1095,1095,R81P,-0.01483925,-0.69609483,-1.9631276290000002,-2.303597255,-3.0626889810000004,0.020189225,-0.017343092,-0.012335408,0.052303867999999996,-0.668372719,-0.7238169409999999,-1.987376085,-1.9388791719999998,-2.271392863,-2.335801647,-2.761573541,-3.36380442,1.542243778,-0.077424439,-12.05395426,-11.28890859,-12.19080585,-12.91754662,-11.75264608,-12.11986417,-10.47997372,-8.924126087000001,-1466.4649626980536 -1096,1096,R81S,-0.058701185,-0.018177864,-0.047342122,-0.063619816,-0.725978424,0.018582156000000002,-0.090715627,-0.026686742000000003,0.036326305,-0.029540699,-0.006815029,-0.039176572,-0.055507670999999995,-0.089006931,-0.0382327,-0.558122376,-0.8938344709999999,2.637138447,2.8025822989999996,-8.082844467000001,-7.68767189,-7.857932404,-8.149855293,-8.649837311,-8.068925437999999,-6.28861819,-3.10536493,-1452.3561337934807 -1097,1097,R81T,-0.08529094,-0.034426002000000004,-0.036001014,-0.016455654,-1.7759954980000001,0.04017739,-0.08787570800000001,-0.082706171,-0.002839185,0.008759449,-0.077611452,-0.007364546,-0.064637481,0.0030162009999999996,-0.035927508,-1.4337760480000001,-2.118214947,0.7494570690000001,1.328478104,-8.578649541,-7.802854583999999,-7.99684375,-8.750476943999999,-9.053988937,-9.289083488,-6.637558929,-3.444158613,-1452.5154399038292 -1098,1098,R81W,-0.08974804300000001,-0.010538216999999999,-0.045731472,0.010094935,-1.456464756,0.0027228940000000004,-0.07125141900000001,-0.10824466599999999,0.000596738,0.029746319,-0.050822753,0.0013326739999999998,-0.09279561800000001,0.059017517,-0.038827648,-1.582226414,-1.3307030979999999,0.33883221799999996,1.304335829,-10.58305488,-9.950487396,-11.05831363,-11.6150691,-9.473591599,-10.81781265,-7.966318982000001,-4.033403742,-1457.200653010048 -1099,1099,R81V,-0.052987957,-0.040181674,-0.054805575,-0.053949295,-1.659967983,0.022825507999999998,-0.086713906,-0.019262007,-0.028455652999999997,-0.020298015,-0.060065332,-0.006401751,-0.10320939800000001,-0.031716881,-0.076181708,-1.417848297,-1.902087668,0.8175539159999999,1.335688426,-9.648307803,-8.572995628,-9.30253653,-11.75603367,-9.166711998,-9.443261192000001,-7.673170004,-4.873921903,-1456.8642734913155 -1100,1100,R81Y,-0.031394298,-0.003046713,-0.0157521,-0.006147488,-0.680618794,-0.019064964,-0.050582142000000004,-0.012206453,-0.029537555,-0.004107189,-0.001986237,-0.042051640999999994,0.010547441999999999,-0.019286094,0.006991118,-0.635358954,-0.725878633,0.849181324,1.447754335,-11.56392999,-11.493609199999998,-12.70887596,-11.64326144,-10.271834199999999,-11.70206918,-8.050760456,-2.897884873,-1455.3852908811532 -1101,1101,V82A,0.02364608,0.00657732,0.022050464,0.010293498,-0.11599150800000001,0.049146985,0.04257509,0.00471707,0.040949753,0.019986003000000002,-0.006831363000000001,0.023909008,0.02019192,0.00474556,0.015841436,-0.09631918099999999,-0.135663835,1.302304122,2.266527397,-4.6474002610000005,-3.408050621,-4.909441437,-3.566066582,-5.317224648,-6.036218018,-2.267512075,-0.787048559,-1456.983922551386 -1102,1102,V82C,-0.012873497,-0.00978831,0.001146796,0.001306052,-0.161156887,0.07720748,-0.022516196000000002,-0.003230798,-0.009759837,0.035038741,-0.05461536,0.037105801,-0.03481221,0.037451523,-0.034839418999999996,-0.086343059,-0.235970714,1.458823433,2.5991132059999997,-9.147447332999999,-6.947304535,-9.09932254,-9.024100281,-10.51731407,-10.14919524,-5.475818752,-4.047848571,-1455.2285985699855 -1103,1103,V82E,-0.059003195999999994,0.053682252,-0.002924168,-0.09608156400000001,-1.8946938290000002,0.077585552,-0.016096831000000002,-0.101909561,0.17430035100000002,0.01900518,0.088359324,-0.022771613,0.016923277,-0.026206074,-0.16595705300000002,-1.6854088719999998,-2.103978786,0.839385899,1.3196498140000001,-9.44456954,-9.024781723,-8.923182022,-8.439155861,-8.446253319,-12.38947478,-5.451898495,-3.528226316,-1453.3464816524647 -1104,1104,V82D,-0.078538422,-0.069542888,-0.058260386,-0.7914231540000001,-1.850754,0.029783281,-0.071522892,-0.08555395199999999,0.013721259,-0.055964568,-0.083121207,-0.047862265,-0.068658506,-0.558429747,-1.02441656,-1.71252529,-1.988982709,1.941869632,1.553586766,-10.15743529,-9.583403831,-7.125161446,-9.646863174,-10.81224039,-13.61950761,-5.117557733,-3.3922258889999997,-1457.643881836906 -1105,1105,V82G,-0.040222061,-0.0062716790000000005,-0.031501978,-0.138420779,-1.77800061,0.07144250099999999,-0.013028369,-0.067415753,-0.22156664899999998,-0.004367659,-0.008175698,-0.037897592,-0.025106364,-0.06462538799999999,-0.21221616899999998,-1.584244913,-1.971756307,0.752884442,1.320207154,-9.676449418999999,-10.06672876,-9.425390625,-7.787416611,-8.633965309,-12.46874579,-4.254121747,-3.499390659,-1457.8743913299404 -1106,1106,V82F,-0.031345183,-0.007771254,-0.039456959,-0.020351678999999998,-1.633488879,0.032345099,0.0033134909999999996,-0.066003856,0.104183515,0.00012154,-0.015664047,-0.013172891,-0.06574102700000001,-0.005633079,-0.035070278999999996,-1.50128468,-1.7656930769999999,0.586450482,1.31512768,-11.0659356,-11.07965033,-11.01479855,-9.10072644,-9.669673569,-14.46482912,-6.019152891,-3.1897140439999996,-1454.0455097402446 -1107,1107,V82I,-0.018774182,0.014332528999999998,-0.0042989840000000005,-0.012213768,-0.06747542200000001,0.041422819,0.00141366,-0.038962024,0.020203386,0.045709423,-0.017044366000000002,0.023198406,-0.031796374,0.017611902,-0.042039438,-0.046753135999999994,-0.08819770800000001,1.2133435590000001,2.3989563869999997,-3.3794687239999996,-3.330043068,-2.793114372,-3.2392656630000003,-3.8919751739999997,-3.642945343,-1.7010873530000001,-1.168657654,-1454.7938270010054 -1108,1108,V82H,-0.023783006000000002,-0.040903918,0.004089641,-0.044471660999999996,-0.512638539,0.092888544,-0.013847672,-0.033718339,-0.018741136000000002,-0.002348656,-0.079459179,-0.024465057999999998,0.03264434,-0.00027524200000000003,-0.08866808,-0.346971627,-0.678305451,0.855719929,1.5676554040000001,-9.467669061,-9.169349709,-8.645125046,-9.460372177,-7.645638152999999,-12.41786022,-4.46330427,-2.680930702,-1449.5170334680006 -1109,1109,V82K,-0.041214192999999996,0.019099755,-0.027513819,-0.027753198,-1.543739055,0.060878349000000005,-0.025113066,-0.057315319,0.388180171,0.035380287999999996,0.002819221,-0.039501048999999996,-0.015526588000000001,0.0009497939999999999,-0.05645619,-1.632879309,-1.454598801,0.72628651,1.3156305190000002,-8.873556502000001,-9.74367495,-8.512688156,-8.347307198,-6.9497876970000005,-10.81432451,-3.9874037510000004,-3.477587174,-1449.0866169226356 -1110,1110,V82M,-0.068743266,-0.012698853999999999,-0.01737977,-0.04834492,-1.392685652,0.072471692,-0.020541655,-0.116944876,-0.126729644,0.042770717,-0.068168425,0.014050816,-0.048810356,-0.001215627,-0.095474213,-1.4068491280000002,-1.378522175,0.6487829279999999,1.322662941,-8.47711888,-8.170028397000001,-8.728244576,-7.295127852999999,-7.146078285,-11.04611529,-5.409819682,-3.230782262,-1449.1143764029257 -1111,1111,V82L,-0.052796090999999996,0.010679283999999999,-0.024765829,-0.077961666,-1.847136171,0.11714804,-0.022602367999999998,-0.082989813,0.00428324,-0.003998797,0.025357364,-0.020066959,-0.029464697999999998,-0.038125001,-0.11779833,-1.659532143,-2.0347401990000002,0.759445048,1.316529467,-6.8948638529999995,-7.161237907,-7.35237542,-6.1226580120000005,-5.122457077,-8.715590851,-3.778675433,-1.9220325919999999,-1444.7966520027258 -1112,1112,V82N,-0.047923674000000006,0.004200988,-0.004557653,-0.021605915,-2.000244548,0.081369188,-0.039049658,-0.056797689000000005,-0.037788561,0.036353376,-0.027951401,-0.003224453,-0.005890853000000001,-0.013352646000000001,-0.029859182999999997,-1.424794087,-2.5756950080000003,0.69210085,1.324587508,-9.815535732999999,-9.760730773999999,-9.20993589,-8.805533226,-8.534450828999999,-12.76702795,-4.542852859,-2.636820663,-1455.547354648821 -1113,1113,V82Q,0.016821400000000004,0.025459227,0.012456552,0.031384089,-1.4728260119999999,0.059906694,0.043896261,-0.010253461,0.001235547,-0.049291389000000005,0.100209843,-0.006590596,0.0315037,0.039168805,0.023599372,-1.443618957,-1.502033067,0.705085727,1.324073152,-7.719080127000001,-8.13672583,-7.440542206,-6.9485734710000004,-6.264174324,-9.805384804,-4.8781962860000005,-4.043456638,-1450.3192608477548 -1114,1114,V82P,-0.060577883,-0.444607139,-1.805983155,-2.313036301,-2.960805997,0.066681031,-0.045552040999999995,-0.075603725,-0.015154869,-0.348339794,-0.540874483,-1.729608552,-1.8823577569999999,-2.086410972,-2.5396616290000003,-2.589841189,-3.3317708039999996,2.898189882,1.123066537,-12.06667736,-11.55962688,-11.63977038,-11.39539185,-11.51399146,-14.22460622,-7.130731583999999,-6.410174892000001,-1459.721283113584 -1115,1115,V82S,-0.013675603,-0.017376661,-0.024745926,-0.020762809,-0.6543946820000001,0.065393824,0.0057236940000000005,-0.033074900000000004,0.030088794,-0.007746736,-0.027006586000000003,-0.028954336,-0.020537515,-0.025118663,-0.016406953999999998,-0.450547638,-0.8582417259999999,1.17377588,1.6660552419999999,-7.909236185,-6.307212875,-8.508007462,-6.696260139,-7.11675856,-10.91794189,-3.533072753,-1.8291327030000002,-1456.220176400151 -1116,1116,V82R,-0.012756503999999998,0.014615683999999999,-0.008757603000000001,-0.016316637,-1.5383483409999998,0.07354786599999999,0.015530325,-0.041043333,0.073139461,0.004136941,0.025094427000000002,-0.029440592999999998,0.011925388,-0.035566613,0.00293334,-1.409227671,-1.66746901,0.8236145709999999,1.3360488640000001,-8.512771008,-8.73029496,-8.85192524,-9.373841057,-5.716705711,-9.891088073999999,-4.416342965,-2.7442010760000004,-1446.9310767021962 -1117,1117,V82T,-0.052854029000000004,-0.021538877999999997,-0.01449999,-0.01136095,-0.458571735,0.087370302,-0.022969603999999998,-0.082738454,-0.20812749100000003,0.023438956,-0.066516712,0.01566734,-0.044667319000000004,-0.002291039,-0.020430861,-0.348260726,-0.568882743,0.968915868,1.644018406,-7.23696767,-6.5613636170000005,-6.701391677999999,-6.385270432,-7.557248085,-8.979564537,-4.389713005,-2.836076644,-1461.3337544729002 -1118,1118,V82W,-0.000279048,0.034775789,-0.010688762,-0.00051615,-1.504499223,0.033329727999999996,0.012673876,-0.013231971,-0.14693303,0.021637745,0.047913832,0.02195761,-0.043335133,-0.015612948,0.014580649,-1.294401516,-1.714596929,0.794965875,1.34204934,-11.88271622,-11.70707121,-12.24678862,-10.80878152,-10.6539921,-13.99694765,-7.065927137999999,-6.523346105,-1455.2388243409805 -1119,1119,V82Y,-0.100965825,-0.068454665,-0.060176226,-0.059228178,-1.331138427,0.006738443,-0.097752696,-0.104178954,0.087150176,-0.001023239,-0.13588609,-0.013939246,-0.106413206,-0.035440396,-0.08301596,-0.968995306,-1.6932815469999998,0.888955534,1.389953297,-11.88190003,-11.32664417,-11.14407112,-10.08856184,-10.84800731,-16.00221573,-5.330620742,-3.288971544,-1453.569488203153 -1120,1120,D83A,-0.143561675,-0.077570233,-0.043032293,-0.082331328,-1.691802754,0.006720323,-0.117421006,-0.169702343,0.013509291000000001,-0.030007764,-0.12513270199999998,-0.017870126,-0.068194459,-0.030963038,-0.133699617,-1.530732881,-1.8528726269999998,0.59473498,1.313506819,-8.519157535,-6.152644264,-8.595246207999999,-12.61904709,-6.224148727,-9.004701386,-4.721784029,-1.446622053,-1446.675930632744 -1121,1121,D83C,-0.118593263,-0.08873477199999999,-0.022321828999999998,-1.3846417640000002,-2.6887639219999997,0.076148557,-0.088627235,-0.14855929,-0.021465397999999997,-0.09406313599999999,-0.083406408,-0.019283795,-0.025359862,-1.234441939,-1.5348415880000001,-2.171129604,-3.20639824,2.274892404,1.470178547,-13.89365689,-11.69398572,-14.1157723,-18.0742255,-12.02309994,-13.56120098,-9.177172791,-6.657912106,-1455.6814326462336 -1122,1122,D83E,-0.009370508,-0.002254833,0.04483406,-0.005885425,-0.09605175199999999,0.015333734,-0.019521708000000002,0.0007806930000000001,0.01627343,0.024349898,-0.028859562999999998,0.05672539099999999,0.032942728,-0.017884594,0.006113745,-0.092954356,-0.099149148,1.2738711120000001,2.314091754,-4.65389301,-3.583685799,-4.621085953,-7.125994307999999,-4.160987114,-3.777711876,-4.141857461,-0.83423194,-1453.1637916872278 -1123,1123,D83G,-0.073048334,-0.050513363,-0.026441369,-0.10738702,-1.86508199,0.056989477999999996,-0.075360657,-0.07073601,-0.062158255999999995,-0.022319019,-0.078707706,-0.015416006000000001,-0.037466731,-0.07831421599999999,-0.136459823,-1.668188726,-2.061975253,0.8085623940000001,1.318748343,-9.050316156000001,-6.476024727,-9.44026255,-12.43665324,-7.560489067000001,-9.338151192,-6.669162387,-3.191356227,-1459.1990196895786 -1124,1124,D83F,-0.100942685,-0.05938765,-0.693523178,-1.763186097,-2.7042285,-0.031874635,-0.053523812999999996,-0.148361557,-0.067506537,-0.056850945,-0.061924355,-0.481617704,-0.905428652,-1.806536775,-1.7198354180000002,-2.518284614,-2.890172386,1.714657734,0.812253335,-14.83520027,-13.224511800000002,-14.54475845,-19.77143609,-13.35689011,-13.27840491,-8.714902588,-5.54722907,-1457.1933147716336 -1125,1125,D83I,-0.06319135599999999,-0.07435249299999999,-0.078379838,-1.624806584,-2.0169373090000002,-0.050926484,-0.076211955,-0.050170757,-0.10930345400000001,-0.093428941,-0.055276044,-0.03394733,-0.122812346,-1.5080074540000001,-1.7416057130000002,-2.051350862,-1.982523755,1.264451243,0.775584791,-14.28678784,-13.83390658,-13.79460052,-18.30379232,-11.19114969,-14.31049007,-8.226362598,-5.824854521000001,-1444.2224805490114 -1126,1126,D83H,-0.040206122000000004,-0.021761912999999997,0.014776724,-0.89984618,-2.269238258,0.028223766,-0.045361045,-0.035051199,-0.020002773999999997,-0.052112566,0.008588741,-0.012141029,0.041694476,-0.6619798339999999,-1.137712525,-1.937293507,-2.601183008,1.778420294,1.387911765,-8.782961143,-7.062699951,-8.289400185,-11.947687400000001,-6.671564697000001,-9.943453483999999,-6.451487386,-3.1292459580000003,-1451.5701852072962 -1127,1127,D83K,-0.066975436,-0.062170925999999994,0.015089411,-0.778854708,-2.1947560619999997,-0.014355165,-0.054376851,-0.079574021,-0.026359147000000003,-0.06688298200000001,-0.057458869,-0.003928095,0.034106917,-0.49472931200000003,-1.062980103,-1.895307523,-2.4942046,1.70283385,1.4132134159999998,-9.779066435,-7.842997391,-9.531024261,-13.81035509,-8.239339232999999,-9.471616196,-6.631604959,-2.467816243,-1451.436122035142 -1128,1128,D83M,-0.22410914399999998,-0.042628952000000005,-0.011138499,-1.053161372,-1.688388499,-0.034895092,-0.000627996,-0.44759029100000003,-0.072682259,-0.049474707,-0.035783196,-0.032274267,0.009997269,-0.832414908,-1.273907836,-2.0346479619999998,-1.342129035,2.182409577,1.5571879640000001,-13.53412581,-12.95069685,-13.18175354,-17.60739271,-10.87182018,-13.05896579,-7.001499837999999,-3.756477765,-1448.1080586616881 -1129,1129,D83L,-0.051338605,-0.054474568,-0.234739452,-1.557010919,-2.734828189,-0.074519116,-0.060754964,-0.041922245,0.009934126,-0.05093954,-0.058009596,-0.144246348,-0.325232556,-1.488490555,-1.6255312819999999,-2.401883757,-3.067772621,1.078478698,0.7438535279999999,-13.25972813,-12.93115707,-12.94427644,-17.68989948,-10.22863145,-12.504676199999999,-6.708215899,-4.115099478,-1441.7942402432673 -1130,1130,D83N,-0.006401794000000001,-0.023130018,-0.010393307,-0.09137129199999999,-2.019126225,0.068659931,0.00041739,-0.013220978000000001,0.12263000800000001,-0.022490892000000002,-0.023769143,0.010401968000000001,-0.031188582000000003,-0.09853483,-0.08420775400000001,-1.64263949,-2.395612959,0.9493019890000001,1.330980288,-8.325561273,-6.723494591000001,-7.318970222000001,-10.52313324,-7.812162979,-9.250045334,-6.763334443,-3.1634390210000003,-1456.8011609665118 -1131,1131,D83Q,-0.050964392000000004,-0.060644755,-0.007093006999999999,-0.034668355,-0.307681489,0.049741424000000006,-0.054026252999999996,-0.04790253,0.008411670999999999,-0.04916627,-0.072123239,0.031045121000000002,-0.045231134000000006,-0.023164475,-0.046172235,-0.258154029,-0.357208949,1.184503074,1.828495987,-8.491979831,-6.638057159,-8.752480621,-11.25586845,-7.513218628,-8.3002743,-5.000106645,-2.026122101,-1447.8715346646495 -1132,1132,D83P,-0.045632229,-0.04578213,-1.107685106,-1.8696608890000002,-2.9442891560000004,0.08039247599999999,-0.042558857,-0.048705600999999994,0.01024835,-0.03603298,-0.05553128,-1.0210106140000001,-1.194359598,-1.822325786,-1.9169959909999998,-2.722064107,-3.166514205,2.403499216,1.093923145,-11.95670678,-7.556582855,-12.70277243,-16.56848303,-11.25630791,-11.69938768,-5.638249076,-2.437532398,-1458.0209664329886 -1133,1133,D83S,-0.071765283,-0.054451769000000004,-0.007096241,-0.048088055,-1.653496975,0.060788668,-0.058814077,-0.084716489,0.024441848,-0.053338178,-0.05556536,-0.005111203,-0.009081278,-0.041785833,-0.054390277,-1.454932169,-1.852061781,0.582119371,1.316706729,-9.400484158,-6.341538185,-9.508948952,-13.45557604,-8.23358873,-9.462768882999999,-5.763813821,-1.8187459240000001,-1451.524361462798 -1134,1134,D83R,-0.059269045,-0.05405598599999999,-0.014104799,-1.167210791,-2.109991013,0.021319551000000003,-0.069524413,-0.049013677,-0.027924746,-0.043460467999999995,-0.064651503,-0.015654635,-0.012554962,-0.8488593990000001,-1.4855621819999998,-2.053103354,-2.1668786719999997,2.028604267,1.454498099,-8.791749467,-8.729455292,-6.804651825,-11.909795599999999,-7.370089973,-9.144754646,-5.514707105,-2.391647065,-1449.629076059442 -1135,1135,D83T,-0.121552342,-0.066930593,-0.017447223,-0.159290823,-1.7427471159999999,0.064186385,-0.025454888,-0.217649796,-0.02237912,-0.060446753,-0.073414432,-0.032360832,-0.002533613,-0.130702218,-0.18787942800000001,-1.692576649,-1.7929175819999998,0.883727947,1.321358139,-10.39226464,-7.58237458,-11.14175458,-14.72469881,-7.378234192000001,-11.13426103,-6.491447456,-2.7676608,-1449.648764316924 -1136,1136,D83W,-0.048484868,-0.058698985,-0.80763949,-1.92369875,-2.996894747,-0.03183439,-0.044640554000000006,-0.052329180999999995,-0.017897527,-0.040197128,-0.07720084099999999,-0.748996198,-0.8662827820000001,-1.8831007530000001,-1.964296746,-2.7197873280000002,-3.2740021660000003,2.02523711,0.891066295,-13.78739878,-12.60462251,-12.54378258,-18.12429844,-12.50774976,-13.15654062,-8.640079494,-5.882583966,-1461.646126199048 -1137,1137,D83V,-0.194687721,-0.043709894000000006,0.00433854,-1.1913334740000001,-1.970337587,0.068547263,-0.041454931,-0.347920511,-0.044843707999999996,-0.082044122,-0.005375665,-0.009818369,0.018495448,-0.925719553,-1.456947394,-1.932745058,-2.007930115,2.292506093,1.6327251719999998,-11.96765676,-11.60577998,-11.36696789,-15.98356109,-8.87623877,-12.00573608,-6.386846036000001,-3.516900655,-1443.5875960988924 -1138,1138,D83Y,-0.081532647,-0.042175975,-0.247448463,-1.858446232,-2.889481787,0.061175584000000005,-0.106669741,-0.056395552,-0.067497575,-0.057920317,-0.026431633,-0.140994643,-0.353902283,-1.5197033000000002,-2.197189164,-2.9304211419999997,-2.8485424310000003,1.137069645,0.751699023,-13.7126861,-11.46433321,-14.88670873,-17.7519307,-12.77996906,-11.68048882,-8.263954348,-4.720137402,-1459.0202772766352 -1139,1139,A84C,0.008774747,0.01381661,0.023578695,-0.012594668,-0.438931888,0.078524336,-0.012519162,0.030068655,-0.052781210999999995,-0.0030723240000000004,0.030705543,0.06258254,-0.015425151000000002,-0.012960788,-0.012228548,-0.327870542,-0.5499932329999999,1.028906061,1.673434527,-6.414064891000001,-5.184808876,-7.555640228,-6.472646484,-5.9738189539999995,-6.883409912,-7.05757314,-4.599009324,-1459.2194176404737 -1140,1140,A84E,0.112527629,0.050621837,-0.017094731000000002,0.016002861,-2.34e-05,-0.019062756,0.151369934,0.073685323,0.103381615,-0.034314774,0.135558448,-0.06354565400000001,0.029356192000000003,-0.009165286,0.041171007999999995,-0.126622498,0.12657564699999999,1.383604708,2.246476384,-2.665904166,-1.4761604,-3.562977394,-4.179887238,-1.925609177,-2.18488662,-4.22914663,-0.850942185,-1451.6861693123356 -1141,1141,A84D,0.016112201,-0.011320308999999999,0.028974468,0.037160109,-0.005715479,0.039745903,0.04070601,-0.008481609000000001,0.064345175,-0.031119888,0.008479271,0.060688494,-0.002739558,0.025768941,0.048551277000000004,-0.051240785,0.039809827,1.339562443,2.506177327,-3.6145935710000003,-2.358720139,-4.024892052,-4.492796173,-3.458454063,-3.738105431,-4.706804491000001,-1.775913975,-1448.8217728091404 -1142,1142,A84G,-0.008743023,-0.009919053,0.030297802999999998,0.010604095,-0.024581986,0.028956292,-0.014665586999999999,-0.002820458,-0.000531044,-0.002879435,-0.01695867,0.055663412999999995,0.004932192,-0.0055866859999999996,0.026794875,-0.027716017000000003,-0.021447955,1.184913061,2.456388285,-4.111107758999999,-2.6916045989999997,-4.808729004,-3.9647619780000003,-4.574019615,-4.5164235989999995,-5.287182914,-2.908204527,-1460.0865119318478 -1143,1143,A84F,0.026800011000000002,0.008507744,0.04761136,0.014222851000000002,-0.186143212,0.056387382,0.033728957000000004,0.019871065,-0.008342516999999999,-0.017702443,0.03471793,0.048546125999999995,0.046676592999999995,-0.008500129,0.036945831,-0.21460044600000003,-0.157685977,1.416943555,2.098464661,-9.742337298999999,-6.886958412,-11.34148347,-10.06908424,-9.157087151,-11.25707323,-9.386055015,-8.771873457,-1458.1212384458631 -1144,1144,A84I,0.037544266,0.031125492999999997,0.04637431400000001,0.030265532999999997,-0.013374836999999999,0.047745805999999995,0.017706331999999998,0.0573822,-0.030804663,0.033809134,0.028441851,0.058137827999999996,0.0346108,0.046066204000000006,0.014464862,-0.036157277,0.009407603,1.3819341680000001,2.678932206,-5.435155227999999,-3.36135144,-6.857830795,-5.092120918,-5.079789482,-6.784683502000001,-5.840283682000001,-3.5869814769999997,-1460.4171768166125 -1145,1145,A84H,0.02273299,-0.005790821999999999,0.03668153,0.027081882,-0.000873553,0.004769037,-0.005714326,0.051180305,0.17770935399999999,0.024025791,-0.035607435,0.071683226,0.0016798339999999998,0.028945254,0.02521851,0.012058979,-0.013806085,1.543610422,3.106887046,-4.2702645939999995,-2.596909622,-5.107809273,-4.822845543,-4.561553925,-4.262204605,-5.161538318,-2.412939445,-1456.1708227079362 -1146,1146,A84K,0.058455078,0.033255941000000004,0.07042799200000001,0.046430810999999995,0.027428182000000002,0.045141214000000006,0.045570164,0.071339992,-0.04372667400000001,0.044180667,0.022331214,0.092782456,0.048073528,0.056995298,0.035866324,0.025310252000000002,0.029546112000000003,1.034682754,2.555993639,-1.795460637,-0.88035511,-2.3164036869999998,-2.77899839,-2.25850515,-0.7430408479999999,-3.615480533,-0.7142193809999999,-1467.321774148848 -1147,1147,A84M,0.02976156,0.002512851,0.046822681,0.023207642,-0.009573927,0.023854438999999998,0.026701981,0.032821138,0.018908324,-0.004839512,0.009865213000000001,0.028389658999999998,0.065255703,0.009703195999999999,0.036712088,-0.032788796,0.013640943,1.327300781,2.555607532,-6.478755859,-4.909011314,-8.184231102,-6.7960189589999995,-6.025733703999999,-6.4787842179999995,-6.688696472,-4.630778688,-1460.5213445350528 -1148,1148,A84L,0.038657231,-0.0023488470000000003,0.053646807000000005,0.039411722,0.005085066,0.03857616,0.039297025,0.038017436,-0.028634597999999997,-0.01397469,0.009276996,0.040510951,0.06678266299999999,0.02497658,0.053846862999999995,-0.035698872,0.045869003,1.153938629,2.386782976,-5.273322597,-2.5716356119999997,-7.31011277,-5.772872871000001,-4.77225367,-5.93973806,-5.483421738,-2.178117913,-1457.2679863739759 -1149,1149,A84N,0.06960399,0.034260571000000004,0.060363623,0.042273860999999996,0.037337985,0.061537134,0.076766182,0.062441798,-0.002620552,0.008452504,0.060068637,0.074324158,0.046403087,0.031963674,0.052584047,0.0035543740000000003,0.071121596,1.188288169,2.630149916,-2.8483835330000002,-2.115461937,-3.180437172,-3.194479065,-3.2858681410000004,-2.465671349,-4.767754692,-2.053582197,-1458.5464263185859 -1150,1150,A84Q,0.047819917,0.058947877999999995,0.061433796,0.042319706,0.02005532,0.02742766,0.043594573,0.05204526,-0.046997672000000004,0.11274442800000001,0.005151328,0.070788821,0.05207877,0.037261067,0.047378344,0.022019207000000002,0.018091432,1.179151542,2.7240743039999997,-1.892163843,-0.619951653,-2.269922989,-2.7536371839999996,-2.360191345,-1.457116043,-3.3266108180000002,-0.791436696,-1459.9700023327023 -1151,1151,A84P,-0.023263699,-0.013467298,-0.038051462,-1.563208104,-2.3601396180000003,0.092560235,-0.006461781,-0.040065616,0.067347066,-0.014019996000000002,-0.012914598999999999,0.005180692,-0.081283615,-1.398879891,-1.727536317,-2.204493871,-2.515785365,0.732938674,0.7149348940000001,-6.613263507,-5.107170921,-7.407126511,-7.281639671000001,-6.185678345,-7.084702087,-6.952731985,-4.879590906000001,-1463.254838136956 -1152,1152,A84S,0.029124966000000002,-0.004853581,0.034941138,0.02733236,0.012671526,0.021777934,0.021262958,0.036986973,-0.034898738,-0.033794688999999996,0.024087527,0.049350273,0.020532002,0.013592873,0.041071847,-0.012541746000000001,0.037884798,1.2885980559999999,2.6875951510000005,-2.03665835,-1.270673996,-2.037686455,-2.070626808,-2.3747157519999997,-2.429588737,-3.963402228,-1.544413971,-1460.4829875673167 -1153,1153,A84R,0.059796684,0.014987,0.055523469000000006,0.041662099,0.016879106,0.002524427,0.056410352999999996,0.06318301400000001,-0.039179667,0.008457592,0.021516407999999997,0.045330199,0.06571673900000001,0.018296946,0.06502725200000001,-0.01313214,0.046890352,1.114053806,2.46394564,-2.201205472,-0.7779428629999999,-3.0564672089999996,-2.9899081730000003,-2.273754372,-1.9079547419999998,-4.059759785,-0.383069447,-1466.7245463412255 -1154,1154,A84T,0.012935651999999999,-0.0026622,0.042518823,0.020981884,-0.01452706,0.053745617999999995,0.020620331999999998,0.005250972,0.015256666,-0.001601442,-0.0037229570000000003,0.035022439,0.050015206,0.014545467,0.027418301000000003,-0.039540333,0.010486213999999999,1.31932374,2.550777895,-2.436505905,-1.884270805,-2.362613411,-2.192047783,-2.674392639,-3.0692048869999997,-4.509298514,-1.840575445,-1460.3133396538906 -1155,1155,A84W,0.013481052,0.027025544,0.041726408,0.037018367,-0.395755631,0.053858027,0.012731373,0.014230731000000002,-0.007935481999999999,0.035125746,0.018925341000000002,0.07278689299999999,0.010665923,0.070434078,0.0036026559999999997,-0.275654079,-0.5158571829999999,1.383502477,2.0215677469999997,-8.660062907,-6.412333167999999,-10.0998651,-8.99853418,-8.238330864,-9.551251228,-8.345260108,-6.622117527,-1456.092804997228 -1156,1156,A84V,0.020949721,0.0029622,0.007884575999999999,0.041511479,-0.020480268,0.065518442,0.00844634,0.033453101,0.015432886000000002,-0.013781203,0.019705602,0.029632972,-0.013863821,0.033212726,0.049810230999999996,-0.044137489,0.003176954,1.368030563,2.636979071,-4.840387595,-3.3959091189999997,-6.2883246,-4.171610519,-4.577073227,-5.769020508,-5.2737693,-3.5126119439999997,-1462.610371678602 -1157,1157,A84Y,0.008516349,-0.0033431809999999998,-0.005425017,0.031171412000000003,-0.150514537,0.081910934,0.002192823,0.014839875,-0.038725146,-0.004800118,-0.001886244,0.028699593,-0.039549627000000004,0.010116712,0.052226111,-0.161804396,-0.139224677,1.448061782,2.238368622,-7.326366263,-4.669548775,-8.978424103,-7.507943794,-6.907978554,-8.567936089,-6.623514561,-4.225877116,-1454.8064269707538 -1158,1158,G85A,-0.045494527,0.005673465,-0.004675723,-0.02002461,-0.134062149,0.011551997,-0.057938535,-0.033050519,0.055082083,-0.012872828999999999,0.024219759,-0.00371771,-0.005633735,-0.045680644000000006,0.005631424,-0.114959144,-0.153165153,1.23583949,2.142959763,-4.970801604,-4.923278427,-5.277532082,-6.17622168,-4.890285637,-3.586690193,-4.815866686000001,-4.215600771,-1457.3338299635798 -1159,1159,G85C,-0.06762691900000001,0.016737244,-0.038478899999999996,-0.045145997,-1.4026250319999998,0.05800635,-0.075561441,-0.059692395999999995,0.190041181,-0.042646283,0.07612077,-0.019954096,-0.057003702999999996,-0.035624324,-0.054667669,-1.238052925,-1.5671971390000001,0.842010044,1.351381989,-7.5835370410000005,-6.810353957999999,-7.899863777,-8.976203177999999,-6.612146507,-7.619117782999999,-7.462001985,-6.134910324,-1464.3277103002183 -1160,1160,G85E,-0.04912052,0.026280801,-0.007104728,-0.023936673999999998,-0.088473564,0.026864835,-0.056829407,-0.041411632000000004,0.14473655300000002,0.003427628,0.049133973,-0.026336731000000002,0.012127276000000001,-0.036793574,-0.011079773000000001,-0.114638789,-0.062308338,1.5054119730000002,2.394398974,-5.281595103,-5.09466008,-4.939381897,-7.1866980289999995,-4.05875148,-5.128484032,-4.8778048730000005,-3.20831146,-1459.2942382209003 -1161,1161,G85D,-0.056540105,-0.063261732,-0.04905168099999999,-0.04509012900000001,-0.106921018,0.038850182999999996,-0.030706575,-0.082373634,0.23215111600000002,-0.005545258000000001,-0.120978205,-0.007314593,-0.090788768,-0.048724085,-0.041456172,-0.087078791,-0.126763244,1.3641896409999998,2.335292185,-5.277745706,-4.498427521,-4.515184608,-7.504985405,-3.9249017489999996,-5.9452292479999995,-4.729393883,-2.479800896,-1461.3773316419683 -1162,1162,G85F,0.029152246,0.038798721,0.011852151000000002,-0.0037735959999999997,-0.6155449789999999,0.010589737,0.002068819,0.056235673,0.067676152,0.018356261000000002,0.05924118,0.018218181,0.00548612,-0.015916751,0.00836956,-0.559543385,-0.671546573,0.979244007,1.5190843569999999,-9.860517162,-8.76168885,-10.76290843,-11.19643118,-8.416792053,-10.16476529,-9.186646766,-10.17688797,-1461.7831000946462 -1163,1163,G85I,0.015318501000000002,0.035779289,-0.001290188,-0.199866711,-1.5315992859999998,0.07454902599999999,0.025537028,0.005099973,0.171981775,-0.05664302,0.128201597,-0.051904676,0.04932430000000001,-0.170623343,-0.229110079,-1.6431328040000002,-1.4200657680000002,1.1407864620000001,1.3526396969999999,-9.193322557,-7.937546707,-10.29889357,-10.513065800000001,-7.5264435039999995,-9.6906632,-7.680020476,-7.08504776,-1462.6490836278535 -1164,1164,G85H,-0.010170774,-0.010804266000000002,-0.046503315,-0.039984248,-0.051679095999999994,-0.069309183,-0.063053687,0.04271214,0.125281636,-0.017018927,-0.004589604000000001,-0.025378592999999998,-0.067628037,-0.064382016,-0.015586478999999999,-0.057251171,-0.046107021,1.405395516,2.450834117,-5.7648331960000005,-5.03192424,-6.55672007,-6.691097038,-4.786579185,-5.757845444,-5.058254541,-3.9799092239999996,-1459.2628595950082 -1165,1165,G85K,-0.006298399999999999,0.03045023,-0.0008542310000000001,-0.038739607,-0.033350538,-0.021819678,-0.021804072,0.009207271999999999,0.090010349,-0.013245934,0.074146394,-0.020786218000000002,0.019077756,-0.047550675,-0.029928537999999998,-0.061938945,-0.00476213,1.2356145920000001,2.3162053119999997,-3.638664856,-2.82105101,-3.845787033,-4.947062103,-3.0862709660000003,-3.493153168,-3.787463349,-2.9761541,-1461.3429071870632 -1166,1166,G85M,-0.029473892,0.031363942,-0.014045542,-0.024594839,-0.18668588100000003,0.025720771,-0.058357623,-0.000590161,0.10503039199999999,-0.013784979,0.076512862,-0.002833688,-0.025257396,-0.046899424,-0.002290254,-0.16120553099999999,-0.212166231,1.469862864,2.251062208,-8.223594408,-7.0570102310000005,-9.171116394,-9.619933357,-6.936675888,-8.333236167999999,-7.316257679,-6.587449024,-1460.8095584078692 -1167,1167,G85L,-0.057280909000000005,0.018847409,-0.00990461,-0.031534822000000004,-0.424891033,0.055974327000000004,-0.070847705,-0.043714113,0.123635323,-0.007331888000000001,0.045026706,-0.0031839990000000003,-0.016625221000000003,-0.04238674,-0.020682904,-0.374399593,-0.47538247200000006,1.315392613,1.814269891,-7.740498155,-6.5124631420000005,-8.906674469,-8.98989608,-6.202539268,-8.090917816000001,-6.671122375,-5.9947101,-1458.007545497734 -1168,1168,G85N,-0.006804173,-0.038492386,-0.023017627000000002,-0.013579932,-0.07667470900000001,-0.006625206999999999,-0.03638781,0.022779464,0.237828249,-0.040351158,-0.036633612999999995,-0.032603912,-0.013431341000000001,-0.073011449,0.045851585,-0.106606295,-0.046743123,1.363723155,2.254357076,-4.365600484,-3.910720848,-4.397990288,-5.8779802860000006,-3.8719850389999997,-3.769325958,-4.564714529,-3.0329104360000003,-1460.1366718388163 -1169,1169,G85Q,-0.023386707000000003,0.011642429,0.0049370379999999995,-0.017618004,-0.025383443,-0.008512774,-0.052286955,0.005513542,0.101471158,-0.025219187999999997,0.048504045,0.015462004,-0.005587929,-0.046284875999999996,0.011048869,-0.05312828,0.002361395,1.268116262,2.3377582390000002,-5.184446939,-4.534344376,-6.053871704,-6.138254997000001,-4.353173233,-4.842590385,-4.537664691,-3.430987942,-1459.0585401682183 -1170,1170,G85P,-0.076432019,-0.073465251,-1.355532061,-2.145045111,-2.908875342,0.015316943000000001,-0.066059386,-0.086804652,0.167450749,-0.016924125,-0.130006376,-1.2721139,-1.438950221,-2.0237441730000003,-2.266346048,-2.751144509,-3.066606175,2.366541,0.928534959,-8.436407391,-7.892549788999999,-8.897169891,-9.590136047,-7.730106972000001,-8.072074257,-7.93289289,-7.08504787,-1466.9737867992371 -1171,1171,G85S,-0.033985428,-0.001685295,-0.031968005,-0.027776754,-0.164970784,-0.011824446,-0.048477234,-0.019493622,0.09057981400000001,-0.029448343999999998,0.026077755,-0.029067772999999998,-0.034868236000000004,-0.043249126,-0.012304381999999999,-0.17218437399999997,-0.15775719300000002,1.4341729269999999,2.191746645,-5.244926497,-5.034703766,-5.3297528530000005,-6.3229169160000005,-5.505439095,-4.031819855,-5.4030092210000005,-4.03245545,-1458.7267050645314 -1172,1172,G85R,-0.050108415999999996,0.0053667359999999996,-0.024332338,-0.031185887000000002,-0.1023798,0.014703173,-0.055652151,-0.04456468,0.119362392,-0.005105665,0.015839137,-0.011814426999999999,-0.036850249,-0.026155582,-0.036216192,-0.10063032599999999,-0.10412927400000001,1.453623291,2.403376724,-4.997319452,-4.016695465,-6.023374649,-5.952515419,-3.6204244919999997,-5.373587235,-4.878773333,-3.451941563,-1458.54727022117 -1173,1173,G85T,-0.08305449200000001,-0.022286671,-0.029338822999999997,-0.051329989000000006,-1.2822142440000002,0.049189183,-0.08523439,-0.080874593,0.147091687,-0.02350772,-0.021065622000000003,-0.009601425,-0.049076220999999996,-0.042263032,-0.060396945,-1.1402891609999999,-1.4241393269999998,0.659829284,1.339298508,-6.297128513,-5.6832192,-6.95415818,-7.038778946,-5.765471893,-6.044014343,-5.786376892000001,-4.814866976999999,-1460.375185051933 -1174,1174,G85W,-0.048077875,0.034556368,-0.007826867,-0.0071251380000000005,-1.596722025,0.08544188800000001,-0.042624052,-0.053531697,0.131527655,-0.00306906,0.072181795,-0.0024782370000000003,-0.013175497,-0.009351986999999999,-0.004898289,-1.581319765,-1.612124285,0.670212756,1.318099578,-9.222419188,-7.8886992110000005,-9.379488853,-10.76473759,-8.083603652999999,-9.995566627999999,-8.144355623,-7.748490007999999,-1460.7600011280738 -1175,1175,G85V,-0.061125331,-0.002129729,-0.02687701,-0.044892332,-1.542004165,0.021949445,-0.053576684000000006,-0.068673977,0.08325443,-0.029124131,0.024864674,-0.015270648999999999,-0.03848337,-0.021715933,-0.068068731,-1.607405625,-1.476602705,0.7692721840000001,1.31963984,-8.010738562,-6.866942184,-8.940439078999999,-9.345921882999999,-7.211634285,-7.688755379,-6.685152382,-5.403878074,-1463.6811943957582 -1176,1176,G85Y,-0.04462753,-0.022910233999999998,0.001453778,-0.05057197099999999,-0.7941742559999999,-0.026840877000000003,-0.066831562,-0.022423497999999997,0.011931118000000001,-0.040263047,-0.00555742,0.014483895,-0.011576339,-0.07711136,-0.024032581,-0.545222757,-1.043125754,1.6894682109999999,1.9506647419999998,-8.647571689,-7.601936867,-9.282961617,-9.912909897,-7.23850341,-9.201546654,-7.2866114379999996,-6.688132427,-1461.3818723363802 -1177,1177,Q86A,0.010585303,-0.054818768,-0.03879968,-0.008917203,-0.031346184,0.014052771,0.012010375,0.009160231,-0.018123461,-0.054414619000000004,-0.055222917,-0.027080872000000002,-0.050518487,-0.013683558,-0.004150847,0.010314100999999999,-0.073006469,1.3223779759999998,2.673405999,-2.752754758,-2.89783725,-2.209007782,-2.4250490719999998,-3.4945196689999998,-2.7373600160000002,-3.1006541480000003,-0.468632063,-1464.7576741371304 -1178,1178,Q86C,0.056980234000000005,0.005079040999999999,-0.053058544000000006,-0.060903585999999996,-0.321765932,0.054265308,0.050612104000000005,0.063348364,-0.050647145,-0.031272522999999997,0.041430603999999996,-0.124991973,0.018874886,-0.092022596,-0.029784576,-0.031664545,-0.6118673179999999,1.264408989,2.364101861,-6.845409148,-7.045994117999999,-6.897099387999999,-6.254165146,-7.261225014,-6.768562072999999,-6.431794699,-3.3686861219999997,-1461.908349131234 -1179,1179,Q86E,0.014009057,-0.02905182,-0.033168435,-0.027986847999999998,-0.036396335,-0.03514691,-0.002393708,0.030411821000000002,-0.045185489,-0.037197226,-0.020906413000000002,-0.058880744000000006,-0.0074561259999999996,-0.048213451,-0.007760245,-0.003490753,-0.06930191599999999,1.25165709,2.497870252,-0.56897356,-0.564854874,-1.385282455,-0.21519980600000002,-0.818287918,0.138757256,-2.5488115280000003,0.7992980909999999,-1456.3871607529 -1180,1180,Q86D,0.012097256,0.008241078,-0.016288709,0.028376834,0.009897319,-0.03610019,-0.011804887,0.035999397999999995,0.06556053099999999,0.066817638,-0.050335482,0.015636893,-0.04821431,0.03915387,0.017599798,0.127961722,-0.108167085,1.137663383,3.1531209639999997,-2.8723349560000004,-3.4580397030000003,-2.707114525,-2.097564301,-3.8369823760000004,-2.261973877,-2.20527596,-0.41184812299999995,-1454.322661348153 -1181,1181,Q86G,0.026653938999999998,-0.010489343,-0.031594417,0.01091036,-0.049850188,-0.004195942,0.014408697,0.038899181,-0.002439801,-0.0036048240000000004,-0.017373862,-0.019889041,-0.043299792000000004,0.005985506999999999,0.015835213,0.049427719,-0.149128095,1.078703398,2.790278556,-4.7233752980000006,-5.032029518,-4.271832893,-4.18420089,-5.016516907,-5.11229628,-4.693500868,-0.25002365,-1455.1227025878616 -1182,1182,Q86F,0.066157602,0.08669586300000001,0.095739492,0.101461242,0.120341129,-0.048221266,0.106588026,0.025727178,0.245639815,0.244898795,-0.071507069,0.23490822,-0.043429237,0.19507813300000001,0.00784435,0.287094218,-0.046411960999999995,0.9165512920000001,3.106668886,-7.558686885,-7.259739692999999,-7.606846161,-6.980115196,-8.072054085,-7.8746792910000005,-6.490177642000001,-3.848821304,-1465.3741083308123 -1183,1183,Q86I,0.010187368,0.012985412,-0.000515842,-0.006363107,-0.039301078999999996,-0.090305139,0.008784131,0.011590605,0.0135243,0.026759105,-0.000788282,0.0051571640000000005,-0.006188848,-0.009526659,-0.0031995540000000003,0.003975811,-0.082577969,1.278431235,2.60751668,-4.15654048,-3.8754557189999996,-3.467368057,-4.636154121000001,-4.3235775069999995,-4.480146996,-3.869006896,-1.102176284,-1468.1319139422849 -1184,1184,Q86H,-0.0069312290000000006,-0.018887575,0.007868559,0.041869927,-0.014527212,-0.019111457,-0.011217685,-0.002644772,0.017644317,0.011237216000000001,-0.049012365,0.041166414,-0.025429297000000003,0.043027765999999995,0.040712087,0.060909713,-0.089964136,1.027434188,2.893681162,-3.9526721310000004,-4.076336052,-4.169997749,-3.417893654,-3.8111143189999996,-4.288018883,-4.042713633,-1.746444251,-1460.8445110237226 -1185,1185,Q86K,0.023142166000000002,-0.038368765,-0.019516181,-0.035926078,-0.009362488,-0.020474255,0.027832027000000002,0.018452304,-0.017611261,-0.055638111,-0.021099418999999998,-0.025556093999999998,-0.013476267,-0.051049198,-0.020802958,0.036046664,-0.054771639000000004,1.1765857709999998,2.5441896880000003,-1.062164688,-0.973031685,-0.557940353,-1.178966225,-1.218440567,-1.382444611,-2.244969801,0.920795435,-1463.8874920425005 -1186,1186,Q86M,0.021486086,-0.053107154000000004,-0.019208793000000002,-0.039024577000000005,-0.015556395,-0.018302093000000002,0.010439200000000001,0.032532972,-0.023963535,-0.062761779,-0.043452528,-0.02808196,-0.010335626,-0.07649837400000001,-0.00155078,0.033250557,-0.064363346,1.182158972,2.665250158,-4.815128294,-4.813691818,-4.605895782,-5.072904900000001,-4.353488983,-5.229659988,-5.070485437,-1.9910955240000001,-1464.673350235913 -1187,1187,Q86L,0.03601063,-0.065855974,-0.057251882999999996,-0.053047971,-0.029438376000000002,-0.048022767,-0.004101392,0.076122652,-0.11901161800000001,-0.11632429,-0.015387656999999999,-0.110540916,-0.003962849,-0.128861518,0.022765576000000003,-0.041051158,-0.017825594,1.424189411,2.419766583,-2.887847513,-3.392307442,-2.124766884,-2.8261766130000003,-2.831946152,-3.2640404739999997,-3.028094817,-0.208691955,-1466.454034339171 -1188,1188,Q86N,0.052813944,0.014941383999999999,0.047311009,0.031959916,0.014918118999999999,0.010668411000000001,0.055055438,0.050572449000000005,0.065201932,0.051709553,-0.021826785,0.082065431,0.012556586000000002,0.05551403,0.008405801999999999,0.09688875,-0.06705251200000001,1.671448915,3.643209181,-3.4242748830000003,-2.729698265,-2.773420929,-4.442790962,-3.748093155,-3.4273711010000003,-5.08503115,-0.732273627,-1460.0940959588625 -1189,1189,Q86P,-0.009947522,-0.044456859,-0.027340155,-0.251576877,-1.368783659,0.014785847,-0.002880681,-0.017014361999999998,0.008951367,-0.005580671999999999,-0.083333046,-0.031291486,-0.023388824,0.053070648,-0.556224401,-0.944686425,-1.7928808930000002,0.649451662,1.3542210430000001,-5.822575835,-6.75347406,-4.318740707,-4.664931084,-5.837925643999999,-7.537807677999999,-4.91839368,-0.384292676,-1460.1813022741117 -1190,1190,Q86S,0.034026422,0.001047659,0.012151944,0.00781268,0.01643971,-0.025380116,0.011065115,0.056987729,0.051857787999999995,0.037775495,-0.035680178,0.023041511,0.001262377,0.021092222999999997,-0.005466864,0.08724432900000001,-0.054364909,1.07861636,2.828609385,-2.5815441480000003,-2.332343132,-2.563018623,-2.588738853,-2.665047859,-2.758572273,-3.6217616510000004,-0.856813655,-1463.108827338554 -1191,1191,Q86R,0.024864589,0.015786256999999998,-0.0067394709999999995,0.015121835,0.007385750999999999,-0.011459622,0.010708428999999998,0.039020748,-0.003486922,0.012550391000000001,0.019022122,-0.005969584,-0.0075093569999999995,0.024096744,0.006146925,0.054593341,-0.039821839,1.543610422,3.106887046,-2.639448869,-3.068323784,-2.20178212,-2.565021729,-2.905449806,-2.4566669080000003,-3.379767771,0.608657632,-1461.1064287703484 -1192,1192,Q86T,0.014450946000000001,0.01220451,0.034871917,0.040506007000000004,0.065980786,0.0008059230000000001,0.004099858,0.024802032999999998,0.11536854099999999,0.063387254,-0.038978235,0.088499541,-0.018755707,0.066634553,0.01437746,0.171481181,-0.03951961,0.983262629,3.008525655,-2.407377893,-1.9517168880000002,-2.712924957,-2.1961353530000003,-2.540507866,-2.635604401,-3.515539468,-0.21152016699999998,-1468.7273887954652 -1193,1193,Q86W,0.01317419,-0.016584198,0.005834941,0.024550323,-0.024832316,-0.02360262,-0.019715075,0.046063455,0.044256397999999995,-0.002153,-0.031015395,0.032596661,-0.02092678,0.042155534,0.006945112,0.076477848,-0.12614248,1.223759613,2.920356167,-7.4031231,-7.381430695,-6.755933402999999,-7.144129486000001,-7.723874313,-8.010247604,-6.551369403,-3.486995392,-1462.8534411201254 -1194,1194,Q86V,0.02515177,-0.0053272169999999995,-0.000314841,0.030028581000000002,-0.0022315029999999997,-0.009557375,0.009316399,0.04098714,0.036916186000000004,0.012136303999999999,-0.022790737999999998,0.013956689,-0.014586371,0.048423533,0.011633629,0.071809238,-0.076272243,1.025394224,2.831263812,-3.6672035480000003,-3.859326523,-3.046392967,-3.701760948,-4.2795098110000005,-3.4490274889999997,-4.401748111,-1.215943085,-1468.5390816805884 -1195,1195,Q86Y,0.01708332,0.064060429,0.047005165,0.075821362,0.037876743,0.000714221,-0.009313247,0.043479885999999995,0.138033242,0.14033513,-0.012214273000000001,0.095895309,-0.001884979,0.168180255,-0.016537531,0.187855542,-0.11210205699999999,1.045878245,3.0479339939999996,-7.934539603999999,-7.373708221,-8.520482262,-7.217358536,-8.229860832,-8.33128817,-6.559336351000001,-3.765829055,-1463.5092770988122 -1196,1196,E87A,0.054883243,0.12666019,0.105446796,0.165353435,-1.004393455,0.09127443699999999,0.043757523,0.066008962,-0.030057431000000003,0.100095635,0.153224744,0.118890068,0.092003523,0.149254478,0.18145239100000002,-1.019388988,-0.989397922,0.495040119,1.333229684,-5.109531859,-4.305268311,-5.23374456,-4.89247052,-4.810771545,-6.305404358,-4.816919586,-0.7656808970000001,-1459.9044301379472 -1197,1197,E87C,0.083543301,0.10035256199999999,0.021368566000000002,0.067982757,-1.900269091,0.028776696,0.07658446099999999,0.09050214,0.042291373,0.005791918,0.194913205,-0.06971994299999999,0.112457075,-0.005863935,0.141829449,-1.6070511580000002,-2.1934870230000003,1.0359992759999999,1.342789724,-10.38377314,-8.949290771,-9.342740807,-12.27384235,-10.2269903,-11.12600146,-8.052197658999999,-4.577108993,-1466.649122318253 -1198,1198,E87D,0.004289735,0.064088914,0.07981806799999999,0.094421639,-0.007214053000000001,0.11259021699999999,0.034187925,-0.025608456,0.037267668,0.029247439,0.09893038900000001,0.03391231,0.12572382599999998,0.049829205,0.13901407300000002,-0.014168354,-0.00025975099999999996,1.1005369090000001,2.511960346,-2.8954628369999997,-2.146538925,-3.6555587010000004,-2.437914207,-2.7525839839999997,-3.484718369,-3.751197849,-1.225791238,-1463.1986597613432 -1199,1199,E87G,0.007300494,0.060079602,0.060965484,-0.326062156,-1.6691985459999998,0.059615249,0.025781863,-0.011180875,0.06534432700000001,0.030266537000000003,0.089892666,0.0011940780000000001,0.120736889,-0.174661995,-0.477462316,-1.845745525,-1.4926515669999998,1.1154742290000002,1.3286593979999999,-6.9905730770000005,-7.133951424,-6.714056786,-6.373129494,-6.809387787,-7.9223398970000005,-4.821822611,-1.001575842,-1459.623765878845 -1200,1200,E87F,0.04914198,0.051986751,0.030353305,0.025354564,-0.292764895,-0.037387451,0.040665562,0.057618397,0.02263839,0.023670926000000002,0.080302575,-0.000231223,0.060937832000000004,0.03474228,0.015966847,-0.3001498,-0.28537999,1.171795417,1.80539168,-10.42113898,-8.35676181,-8.142894821,-13.76812366,-10.19023107,-11.64768356,-6.02970109,-0.818100575,-1459.6686206106097 -1201,1201,E87I,0.09015658,0.029362755,0.05807796900000001,0.088589461,-0.022245569,0.021994293999999998,0.084436439,0.09587672,-0.005943343,-0.05938169099999999,0.1181072,-0.012130446000000001,0.128286383,0.008549631,0.16862929,-0.11780550199999999,0.073314364,1.220664437,2.171555293,-7.880623145,-6.2709324870000005,-6.537848251000001,-10.56727208,-6.8556091079999995,-9.171453796,-4.237217909,-0.143900103,-1453.7527994466946 -1202,1202,E87H,0.047969527000000005,0.051791519,0.01778261,-0.61044485,-1.85153629,0.033351715,0.027467834,0.06847122,-0.039872791,-0.010254558,0.113837595,-0.079695121,0.11526034,-0.38122881,-0.839660889,-1.82429617,-1.878776409,1.5988553769999998,1.4024814209999998,-9.674004613,-8.425328293,-8.942672455,-11.23184199,-9.986610176000001,-9.783570152000001,-6.670784713,-3.444396428,-1463.756290841382 -1203,1203,E87K,0.013536526,0.096589505,-0.114560886,-1.587200639,-2.921329819,0.032324692,0.05148128,-0.024408229,-0.058274234,0.005664195,0.187514815,-0.102857567,-0.126264204,-1.529303485,-1.6450977930000001,-2.355935728,-3.48672391,0.9949777409999999,0.727246155,-7.3930514679999995,-6.133995041,-6.5615001070000005,-8.858368607000001,-7.2631259539999995,-8.148267632,-6.562240975,-2.8571117910000003,-1461.6239636028185 -1204,1204,E87M,0.068093573,0.044894984000000006,0.057469567,0.069565683,-0.031613816,-0.015411293999999999,0.071053867,0.065133279,-0.0386477,0.012640753000000001,0.07714921400000001,-0.018105581000000003,0.133044714,0.010450761,0.128680604,-0.107415018,0.044187387,1.391309677,2.2738131630000002,-9.428950947999999,-7.223950737000001,-7.994802094,-12.29516174,-9.116459679,-10.51438049,-5.698153262999999,-2.433969709,-1457.4098827070557 -1205,1205,E87L,0.081300597,0.022253731000000002,0.051457393,0.057691701,0.024209124,0.00381098,0.057405341,0.105195853,0.02846004,-0.032977778,0.077485239,0.000333529,0.102581257,0.028271808,0.087111593,-0.044644188,0.093062435,1.249082587,2.535920033,-7.294717725,-5.144012169,-6.407903602999999,-10.31099616,-6.403014519,-8.20766217,-4.6396456310000005,1.020998265,-1455.7494614869356 -1206,1206,E87N,0.063549015,0.06770328,0.017724998999999998,-0.21772666899999998,-1.647481185,-0.009383554,0.057490999999999993,0.069607029,0.106891131,-0.019099434,0.154505994,-0.057378454,0.09282845199999999,-0.169533403,-0.265919935,-1.605613572,-1.6893487969999998,1.156391875,1.356477909,-8.230363306000001,-7.046586426,-8.141545563,-8.497781737999999,-8.546940002000001,-8.918962798999999,-6.09893344,-2.798043109,-1463.2637666570954 -1207,1207,E87Q,0.089780716,0.07397422299999999,0.069884161,0.09814517,-1.1763081690000001,0.024947123999999998,0.088517434,0.09104399699999999,0.023194673,0.01691762,0.131030825,0.012606253999999999,0.127162067,0.055443081,0.140847258,-0.945349995,-1.4072663419999998,0.57939509,1.344701524,-5.660011464,-4.589993034,-5.380128426000001,-6.846401016000001,-5.0891289219999996,-6.394405922000001,-4.997555305,-2.506625759,-1462.373709216714 -1208,1208,E87P,0.039084006,0.054488055,-0.956548451,-1.5627208000000001,-2.483551041,0.021973349,0.03843972,0.039728292000000005,0.070408948,0.008229906,0.100746203,-0.9238370440000001,-0.9892598570000001,-1.6266904819999999,-1.4987511180000002,-2.44108827,-2.526013811,2.629287743,1.399998579,-9.59027757,-8.677533363,-9.330235435,-9.814526756,-9.190364647,-10.93872765,-6.823961098,-3.43171913,-1465.631088736467 -1209,1209,E87S,0.06732751,0.067180298,0.060565692000000004,0.027247136,-1.501669116,0.001751896,0.07447203299999999,0.060182985999999994,0.055011633,0.006869431999999999,0.127491164,-0.015493933,0.136625316,0.012197678,0.042296593,-1.52140875,-1.4819294809999999,0.825675763,1.328971383,-7.283317014,-6.682900093,-6.386404563999999,-7.136829201,-7.453746506,-8.756704704,-5.561082207,-1.748758662,-1457.8432517787442 -1210,1210,E87R,0.052542878,0.07353947,-0.366531139,-1.502997067,-2.347803569,0.023305977000000002,0.040682587,0.064403168,-0.014786342,0.0060017230000000005,0.141077217,-0.312222053,-0.420840225,-1.4240238490000001,-1.581970285,-2.219398399,-2.476208739,2.537231438,1.557851047,-8.399886427,-7.9121610570000005,-7.530149826000001,-10.02127084,-8.311711922,-8.224138489,-6.400540251000001,-2.4388929040000003,-1464.0393730923533 -1211,1211,E87T,0.05971782900000001,0.039958258999999996,0.074538331,0.046758354,-0.836128657,0.032342211,0.075538482,0.043897175,-0.010307766999999999,-0.00384867,0.083765188,0.049661355,0.099415306,0.060975779,0.032540928999999996,-0.738611421,-0.933645893,0.6041185379999999,1.3716709569999999,-7.627686154,-6.561831055,-7.017760857000001,-7.97037838,-7.8576400070000005,-8.730820473,-6.157600948,-2.21548644,-1458.6504438952543 -1212,1212,E87W,0.048311982999999996,0.023110037000000003,0.022301841,-0.019671466000000002,-1.558419284,0.028381317000000003,0.051630113,0.044993853,0.040047417,-0.053412885,0.09963295800000001,-0.075100475,0.11970415699999999,-0.030112412999999998,-0.009230518,-1.668311959,-1.448526608,0.8184319090000001,1.320720501,-10.22769793,-7.922635277,-9.544488258,-14.2716673,-10.16517268,-9.234526146,-6.800990402999999,-2.376910186,-1466.1740203774534 -1213,1213,E87V,0.081343989,0.044799356,0.07124581,0.065744569,-0.121958186,0.006778424,0.093958637,0.068729341,-0.036123532,-0.014817104,0.104415815,-0.013312306000000001,0.155803925,-0.011845022,0.14333416,-0.18467427600000003,-0.059242095,1.410200423,2.1405887569999997,-7.547631706000001,-6.13289547,-6.800055481,-10.09403954,-6.070106857000001,-8.64106118,-4.714836989,-0.965267733,-1457.088345722761 -1214,1214,E87Y,-0.005737366999999999,0.048880075999999995,0.024767855,0.050577964,-1.6328803809999999,-0.017911589,-0.02364949,0.012174756,0.089945711,0.028020657,0.069739495,-0.012671848000000001,0.062207557999999996,0.092845106,0.008310821,-1.6968949530000002,-1.5688658080000002,0.571382956,1.305859542,-10.94317333,-9.091825294,-9.292912636,-14.0056796,-10.8393398,-11.48610933,-6.652347876,-2.60354004,-1461.7047472917475 -1215,1215,Q88A,0.032303935,-0.015409259,-0.027838091000000002,0.03415031,-0.00012030000000000001,-0.035432434,0.021772299,0.04283557,0.08842921699999999,0.010011893000000001,-0.040830411000000004,-0.017427823000000002,-0.038248358999999996,0.059166552000000004,0.009134068,0.014003903,-0.014244502,1.179757852,2.671965215,-3.386064307,-2.9231114430000003,-3.8684875560000003,-3.1783070139999996,-3.608939285,-3.3514762339999997,-4.225214262,0.020429423999999998,-1462.214222446084 -1216,1216,Q88C,-0.040941677,-0.073486293,-0.073897993,-0.006473535,-0.273911584,0.100564635,-0.012769836000000001,-0.069113517,0.17245165,-0.08920131199999999,-0.057771274000000004,-0.047888032999999997,-0.099907952,-0.004574954,-0.008372115,-0.174510014,-0.373313154,1.51144349,2.3037967459999997,-8.662211247,-7.426382942,-8.959202347,-9.119914383,-8.223079483,-9.582477081,-7.824141543,-3.374428472,-1461.8045958457515 -1217,1217,Q88E,0.033023935,0.029500985,0.025920347000000003,0.068388539,0.029576106,0.012693642,0.045343303,0.020704567,0.008080748,0.084087575,-0.025085606,0.051842054000000005,-1.36e-06,0.083649352,0.053127725,0.095611985,-0.036459774,1.1711857940000001,2.904147458,-3.439844473,-3.0875554660000004,-4.034687431,-3.5421092000000005,-3.4652821730000003,-3.069588097,-5.064371867,-0.23417693899999997,-1452.9189747907221 -1218,1218,Q88D,0.022855594,0.02456005,-0.005967556,0.043833308,0.077216808,0.004687223,0.035174185,0.010537002,-0.033243537999999996,0.088733325,-0.039613225,0.062220465,-0.074155576,0.07866574,0.009000876,0.082354001,0.072079615,1.1275347009999999,2.9638930930000003,-3.1212624819999997,-3.197294182,-2.8350370330000003,-3.698879784,-3.296120384,-2.578981026,-3.007647053,1.493232928,-1455.4769503539428 -1219,1219,Q88G,0.04705773,-0.009602994,0.00781269,0.049287055,-0.08186091200000001,0.030387405,0.052403639,0.041711821,0.055818228,0.010954182,-0.030160169,0.002488386,0.013136993999999999,0.067006761,0.031567347999999995,-0.07757111,-0.086150713,1.36154686,2.439371247,-6.182214547999999,-6.135061652999999,-5.507951858999999,-6.11832206,-6.757287346,-6.3924498210000005,-5.107864775,-0.526146201,-1458.4320161291398 -1220,1220,Q88F,-0.051611405,-0.001272796,-0.026454515,0.035217414,-0.058579433,0.014499251999999999,-0.047894106,-0.055328704000000006,0.019886128,0.043048404000000005,-0.045593996,-0.057967322,0.005058293,0.072369524,-0.001934696,-0.028456465,-0.08870239999999999,1.260158852,2.6252634930000003,-9.651248251,-9.075219673,-10.56626432,-10.03139586,-9.146704521,-9.436656883,-5.807136816,-0.618946565,-1466.0107325883582 -1221,1221,Q88I,-0.047526307000000004,-0.083006531,-0.033625046,-0.022435838,-0.077210232,-0.019313336,-0.052195751,-0.042856862999999995,-0.00281786,-0.08216966,-0.083843402,0.025494395,-0.09274448699999999,0.0710031,-0.115874775,-0.012328306,-0.142092157,1.3478321180000001,2.8156437619999997,-7.753530051,-8.301544456,-8.267427223,-8.439984612,-6.282780869,-7.475913094,-6.210047906000001,-2.4796190240000002,-1462.925334956497 -1222,1222,Q88H,-0.024172062999999997,-0.038350228,-0.034833697999999996,0.027203092999999998,0.015802767,-0.013159448,-0.00938302,-0.038961106,0.035369685,-0.007643111,-0.069057345,-0.021554512,-0.048112882999999995,0.06510329200000001,-0.010697106000000001,0.020949181,0.010656352,1.129499537,2.631264114,-5.045301858999999,-3.6700244289999997,-6.3296175539999995,-5.682545189,-4.664576599,-4.8797455219999994,-5.725762321,-0.735535917,-1461.4715442610905 -1223,1223,Q88K,0.046121101,0.00634495,0.00645875,0.074857676,0.094749771,-0.010936445,0.063996574,0.028245627000000002,-0.056047229000000004,0.075032865,-0.062342966,0.032622347999999995,-0.019704848,0.080969695,0.068745657,0.097505345,0.091994196,1.077968091,3.00832055,-2.6254966459999998,-1.9973394009999998,-2.664619804,-2.7105236660000003,-3.92558934,-1.829411018,-4.323068997,0.35741959,-1461.5477100117132 -1224,1224,Q88M,0.07591871900000001,-0.023065218999999998,0.023385101000000002,0.054149654000000005,-0.014628486000000001,0.077437063,0.079774818,0.07206261900000001,-0.000933716,0.003549997,-0.049680435,0.005469444,0.041300758,0.052563395,0.055735912,-0.016224552,-0.01303242,1.164682365,2.593359679,-7.143543128999999,-7.852766991,-7.307869286,-7.8255491710000005,-5.65929599,-7.072234207,-6.556273478,-3.074228615,-1464.1018757149577 -1225,1225,Q88L,0.007272375,-0.01590591,-0.014248538,0.053277424000000004,-0.004543879,0.019477542,0.026567536,-0.012022786,0.060152979,0.009905035,-0.041716855,-0.0006582910000000001,-0.027838784,0.054556895,0.051997952,0.0036435879999999997,-0.012731346000000001,1.181087765,2.7348506130000003,-6.93084707,-8.129996185,-7.371398834,-6.923690071,-4.601644165,-7.627506096,-5.094279447,0.177777375,-1462.5939525137655 -1226,1226,Q88N,0.023390104,0.062870117,0.018556473,0.053838135999999995,0.027462082000000002,0.015104343000000001,0.021971547,0.02480866,0.11771519800000001,0.08111906599999999,0.044621167999999996,0.015099266,0.02201368,0.090515013,0.017161258999999998,0.0016160010000000002,0.053308162,1.215283235,2.626997034,-3.558646234,-2.89177607,-3.395999046,-4.811606353999999,-3.8358572239999997,-2.857992477,-4.418844909,0.038828496000000004,-1461.324043486733 -1227,1227,Q88P,0.004069339,-0.002046575,-0.003931544,-1.051082846,-1.9268623630000001,0.04538372,0.033691344,-0.025552667,0.016553503,0.024020714,-0.028113864,-0.014349491,0.006486404,-0.7537054320000001,-1.348460259,-1.832166218,-2.021558507,2.070845646,1.55745784,-7.481086397,-7.668603554,-8.271829117000001,-6.771355301,-6.536837883,-8.156806129,-5.659667868,-0.88914366,-1458.6519988197833 -1228,1228,Q88S,0.04584819,0.017622921,0.001565274,0.052350891,0.023680338999999998,-0.021339893999999998,0.061349062,0.030347317000000002,-0.001454297,0.0217976,0.013448241000000001,-0.004035483,0.007166031,0.059910211,0.04479157,0.037539151,0.009821527,1.0373781690000001,2.727818375,-1.831365651,-1.016592896,-1.6152179340000001,-1.9066915359999999,-2.351303444,-2.267022446,-4.137699422,1.343793049,-1462.1267106886953 -1229,1229,Q88R,-0.01289243,0.005446904,0.007890046999999999,0.03952838,0.016367382,0.003979693,0.024294977000000002,-0.050079835999999996,0.039696112,0.042148257,-0.031254449,0.047994660999999994,-0.032214567,0.068027447,0.011029313,0.050896934000000005,-0.01816217,1.199379632,2.858891578,-2.4828596419999998,-2.144382294,-2.314331551,-3.081089745,-2.605703911,-2.26879071,-4.12925958,0.685969675,-1462.916948037222 -1230,1230,Q88T,0.054437564,0.003298217,-0.005184350999999999,0.059950844,0.023069693999999998,-0.005686804,0.06190093,0.046974197,0.068469876,0.021302752999999997,-0.01470632,-0.014790447,0.004421745,0.070074622,0.049827065,0.023458215,0.022681172000000003,1.188531919,2.805887005,-3.4584377180000003,-3.115571442,-3.218177414,-3.536492599,-3.5212444310000004,-3.900702705,-4.3539349430000005,0.061247845,-1462.0078451125883 -1231,1231,Q88W,-0.41284074299999995,0.0236892,0.031385505,0.09347412,0.052154614,0.0031223809999999996,0.044635009,-0.870316495,0.041508533,0.035905463,0.011472936000000001,0.030721397,0.032049612000000005,0.073282867,0.11366537300000001,0.050221334000000006,0.054087893,1.0882496640000001,2.8629471360000003,-8.837188876,-8.985157631,-8.643806488,-9.485841499,-8.663544563,-8.4075942,-7.052918603999999,-3.6153106839999998,-1466.4526025648229 -1232,1232,Q88V,-0.002694602,-0.011098924,-0.018490376,0.039814456,-0.02038913,0.048306112000000005,0.007917262,-0.013306466000000001,0.127186679,0.043602325,-0.065800172,0.009339336,-0.046320087999999995,0.046639625,0.032989286,0.021582492,-0.062360751,1.178292594,2.721646774,-6.605669193,-7.32097242,-7.009054916,-6.48372123,-5.790046782999999,-6.424550612999999,-5.400797804,-1.205014349,-1461.3761223228648 -1233,1233,Q88Y,0.062750868,0.036273293,0.059185774000000003,0.096223861,0.087859613,-0.040043254,0.055352346,0.070149389,0.000498419,-0.00957765,0.082124235,0.050635757,0.06773579099999999,0.034095971,0.15835175,0.045104045,0.13061518,1.103531468,2.759759629,-10.04468634,-8.867099701,-12.81490498,-10.72910564,-9.906172935,-7.90614843,-6.1642516579999995,-1.175744443,-1466.7989104920998 -1234,1234,L89A,-0.0331373,0.026295917000000002,0.005897541,0.023746114,-1.51750046,0.029461063,-0.050264891,-0.016009708,0.058154965,0.012168565,0.040423269,-0.017321406,0.029116487000000003,0.036463649,0.011028578999999998,-1.395263142,-1.639737777,0.524565597,1.316404986,-6.850393228,-8.54612838,-5.599433121000001,-6.266668236,-4.268734589,-9.571001816,-5.757854804,-3.8387185280000002,-1458.652153395582 -1235,1235,L89C,-0.032035051,-0.047588781,0.000156431,-0.7387073829999999,-2.106335815,0.06663966,0.030760566,-0.094830667,-0.01316245,-0.010253018000000001,-0.084924543,-0.047435914,0.047748776,-0.357219189,-1.120195576,-1.846342595,-2.366329035,1.448092214,1.36903937,-9.333760998999999,-9.996754623,-8.107065094,-10.29357748,-7.340972725,-10.93043507,-8.574270392999999,-7.205445922000001,-1461.5862698606215 -1236,1236,L89E,-0.14424067699999998,-0.005066387,-0.033061639,-0.11934807900000001,-2.122418487,0.067513892,-0.13035629699999998,-0.15812505699999999,0.016589631,-0.035970461,0.025837687999999998,-0.05643070099999999,-0.009692576,-0.037483386,-0.20121277199999998,-1.590093049,-2.654743924,0.606928577,1.312592777,-8.444922304,-9.161046158,-7.516256905,-9.309865532,-5.278616608,-10.95882632,-7.087193859,-4.707221621,-1456.7112983218394 -1237,1237,L89D,-0.028070645,-0.011812418,-0.03718106,-0.567271936,-2.198119647,0.02975867,0.036569785,-0.092711075,-0.104575553,-0.023877187,0.000252352,-0.11035851199999999,0.035996393,-0.240018643,-0.894525228,-1.7906938069999998,-2.605545486,1.337945635,1.3612488880000002,-10.59852311,-11.13122562,-10.50541126,-11.12417969,-7.219189926,-13.01260904,-8.703510343,-6.994136912,-1454.9588186838664 -1238,1238,L89G,-0.08410186800000001,-0.066134403,-0.017140445,-0.09238281300000001,-1.746458061,0.08169702400000001,-0.058392574,-0.10981116099999999,-0.064874377,-0.069999869,-0.062268936,-0.037232239,0.00295135,-0.023834576,-0.160931049,-1.6491433580000001,-1.843772763,0.8097827609999999,1.320241194,-8.905263551,-11.165894300000001,-6.790520821,-7.243362785,-6.352322327,-12.97421752,-6.909456621,-3.674713745,-1460.7407762259245 -1239,1239,L89F,-0.071190157,-0.018021565,-0.054275304,-0.013491771999999999,-1.065589855,0.092708,-0.038948621,-0.10343169199999999,0.063829767,0.014628826000000001,-0.050671955,-0.050521842000000004,-0.058028765,0.012093332,-0.039076876,-0.69421588,-1.436963829,0.9774342229999999,1.48118201,-5.65416026,-4.495923042,-5.155984276,-7.491745323,-4.225370766,-6.901777892999999,-5.755822633999999,-3.207502007,-1453.669116689358 -1240,1240,L89I,-0.057288926,0.017897855,-0.000609927,0.019027822,-0.292830677,0.07447266,-0.052333629000000007,-0.062244222,0.0029923420000000003,0.043046144,-0.007250434,0.003479199,-0.004699053,0.045128678,-0.007073034000000001,-0.222177393,-0.36348396,1.129624275,1.903709181,-4.963014446,-3.959351097,-5.042844704,-6.540368103,-4.2997507630000005,-4.972757561,-6.687052916,-4.071985403,-1462.7247958532535 -1241,1241,L89H,-0.066808811,0.037923032999999995,-0.002138622,-0.09919880199999999,-1.515653905,0.05619785,-0.032363972000000005,-0.10125365,-0.027921802000000003,0.008170796,0.06767526900000001,-0.028204555,0.023927312000000003,-0.042124708,-0.156272896,-1.326619888,-1.7046879209999999,0.62105932,1.325201835,-11.13889943,-11.87304268,-9.646602234,-13.14196828,-7.74784182,-13.28504211,-8.79962263,-7.838990008,-1457.8954905294813 -1242,1242,L89K,-0.09268154,-0.042553043,-0.057566618,-0.9429244290000001,-1.9043932769999998,0.013784418,-0.06931723,-0.116045849,-0.0011868480000000001,-0.038075299,-0.047030786,-0.089104388,-0.026028847,-0.6782218320000001,-1.207627026,-2.045966312,-1.762820241,1.901376091,1.429161537,-7.882206352000001,-8.039312858999999,-6.838080307,-9.410864403,-4.972162872,-10.15061132,-6.648005591,-4.702790255,-1457.2273480435833 -1243,1243,L89M,-0.000443625,0.045658412,0.022507745,0.026469617999999997,-0.068121536,-0.009742648000000001,-0.004588857,0.003701607,-0.01472993,0.06358678,0.027730043,0.024989584,0.020025906,0.054557014,-0.0016177779999999998,-0.036660103,-0.09958296800000001,1.186638969,2.423267269,-4.3301271130000005,-4.464801758,-4.513537842,-4.063312607,-3.514838379,-5.094144981,-4.764745769,-3.0499417689999997,-1460.038270454388 -1244,1244,L89N,-0.107009849,-0.054181648,-0.035920652000000004,-0.88043269,-1.80739076,0.045476998,-0.097235688,-0.11678401,-0.044719852000000004,-0.052161927999999996,-0.056201368,-0.04384728,-0.027994023,-0.486449687,-1.274415692,-1.8237642109999999,-1.7910173090000001,1.736100391,1.44378924,-10.90591121,-11.57756381,-9.295157425,-12.74595065,-8.201983734,-12.70890043,-9.998314173999999,-10.17081188,-1456.788676859811 -1245,1245,L89Q,-0.107186166,0.005015638,-0.052263443,-0.194378665,-1.814728086,0.016471031,-0.097317982,-0.11705435,-0.07618405,0.012991655,-0.00296038,-0.080622997,-0.023903887999999998,-0.057496415,-0.331260915,-1.518780292,-2.11067588,0.792977121,1.325654072,-9.383496912,-10.36147267,-8.377760925,-10.01275784,-6.680069939,-11.48542318,-7.881913441,-6.789696322,-1459.2306805201806 -1246,1246,L89P,-0.09897177800000001,0.013461446,-0.01431799,-0.018416175,-1.452205367,0.081698752,-0.0587332,-0.139210355,-0.019419862,0.044820926,-0.017898034,0.024876274,-0.053512254,0.029419507999999997,-0.066251857,-1.18920866,-1.7152020730000002,0.600028982,1.3323421020000001,-4.349791417,-5.824621719,-3.7667021330000003,-4.10814518,-3.233888092,-4.81559996,-4.568451422,-2.410204968,-1461.3197255684063 -1247,1247,L89S,-0.062074940999999995,0.012466753999999998,0.014875631,-0.039904976,-1.6795782819999998,0.036591066,-0.053425239000000006,-0.070724643,0.008494536,0.0171231,0.0078104080000000005,-0.003398579,0.033149841,0.017010312,-0.096820263,-1.565549464,-1.7936071,0.444772139,1.305615736,-7.523215785,-8.811308662,-5.523319252,-8.365351532,-5.4061026,-9.50999688,-6.389438281,-5.6908856729999995,-1456.127757281065 -1248,1248,L89R,-0.096017579,-0.018799198,-0.041750739,-1.3824425130000002,-2.009935743,0.09354610599999999,-0.056395342,-0.135639816,-0.024210455,0.001923363,-0.039521759,-0.043965622,-0.039535855,-1.090106123,-1.674778902,-1.672840867,-2.3470306180000002,3.092633872,2.351608227,-8.243879688,-8.656393852,-7.563850655,-8.754122261000001,-5.239022522,-11.00600915,-6.83988968,-4.232003412,-1458.2314565526322 -1249,1249,L89T,-0.075303194,0.05099723900000001,-0.022623017000000002,-0.063514654,-1.712095064,0.037857075,-0.047637797,-0.10296859,0.017302295,0.065131414,0.036863063,-0.007854076,-0.037391957,0.020170445,-0.14719975300000002,-1.5442840740000001,-1.879906053,0.63772385,1.31531363,-7.4923834639999995,-8.266606987000001,-6.207190674,-7.900169579,-5.3434867939999995,-9.744463287,-7.020355919,-5.658127192,-1458.918530318886 -1250,1250,L89W,-0.011960913,0.016185593,0.050832994000000006,0.010374732,-1.733268579,0.07607939799999999,0.011712726000000001,-0.035634552,-0.024200127999999998,-0.009695460999999999,0.042066646,0.035453659,0.066212329,0.032927923,-0.012178458999999999,-1.453506344,-2.0130308130000003,0.669867962,1.3218184290000001,-8.652681238,-8.597268486,-9.088394775,-9.872710547999999,-5.025510574,-10.679521800000002,-6.2354838720000005,-3.727466158,-1454.1528030196205 -1251,1251,L89V,-0.06768515900000001,-0.013697971000000001,-0.008251293,0.017593182,-1.52692744,0.051349592,-0.043935337000000005,-0.09143498,-0.075787687,0.004725165999999999,-0.032121107,0.010179981999999999,-0.026682567999999997,0.092129855,-0.056943492000000005,-1.3797746880000001,-1.674080191,0.458850662,1.313222772,-6.540043878,-6.485164795,-6.424135033,-7.324992073,-5.267949127,-7.197978363,-6.179949211,-4.783772744,-1463.7718133926392 -1252,1252,L89Y,-0.075254154,0.0036586120000000003,-0.005657211,0.016827778,-1.435450717,0.113488515,-0.054164685,-0.096343623,-0.019203338,0.048914347999999996,-0.041597124,-0.016534552,0.00522013,0.048502109,-0.014846553,-1.425360386,-1.4455410469999999,0.534130177,1.3150967759999999,-9.192504749,-8.570032767999999,-8.857753357,-11.22088213,-6.385316536,-10.92853895,-6.781709923999999,-3.6356642999999997,-1454.3847218910232 -1253,1253,G90A,-0.013649133,0.031624062,-0.042089287,0.013255168999999999,-0.011699145,0.067484269,0.027236271,-0.054534537,-0.052504123,0.05743088,0.005817243000000001,-0.010191369,-0.073987204,0.065193979,-0.038683642000000004,-0.008293503,-0.015104786,1.169637137,2.558734278,0.34778014700000004,0.502114807,-0.11991011,0.540211647,0.475235489,0.341248901,-0.8677787379999999,1.050190804,-1463.0006966753863 -1254,1254,G90C,0.073141673,0.006536330999999999,0.01349705,0.002004083,-0.975286612,0.107913466,0.056582713,0.089700633,-0.100014197,-0.036596392,0.049669054000000004,-0.063248099,0.09024219800000001,-0.048390006,0.05239817099999999,-0.87078115,-1.079792074,1.0145429259999998,1.436812988,-4.375274692,-3.990473106,-3.9855835039999996,-4.978669463999999,-4.195190437,-4.726456947,-6.109690809,-3.895430461,-1464.309235011693 -1255,1255,G90E,0.02561343,-0.015886723999999998,-0.018965453,0.013572236000000001,0.041201227,0.012981401000000002,0.038608126,0.012618733,-0.052711037,0.005447952,-0.0372214,0.016528821000000003,-0.05445972599999999,0.033237976,-0.0060935040000000005,0.051468814,0.03093364,1.110969013,2.691206778,1.5781998169999998,1.546856384,1.606468582,0.981505455,2.3012014080000003,1.454967255,-0.39748940299999996,1.229441899,-1463.8579700253904 -1256,1256,G90D,-0.060325971,-0.06504227900000001,-0.057216786,-0.032171239,-0.005478861999999999,0.011807307,-0.023678331,-0.09697361,-0.145721249,-0.014955032,-0.115129526,-0.039052177,-0.075381395,0.049052557000000004,-0.113395035,-0.002555197,-0.008402527,1.374463217,2.813746024,2.33596237,2.31446077,1.7322798609999999,1.728860184,3.5145794830000003,2.389631554,1.167093816,2.6197071640000003,-1462.6750712655485 -1257,1257,G90F,0.042628124,-0.024018391,-0.078979982,0.037264197,-0.131499981,0.010466486,0.065979325,0.019276922,-0.12481385,0.040068135,-0.08810491599999999,-0.04900766,-0.108952304,0.0683284,0.006199994,-0.070744268,-0.19225569399999998,1.260296383,2.376456284,-4.29258084,-3.552814285,-3.769783119,-5.788547501,-3.918591888,-4.433167404,-5.321456885,-3.105097895,-1460.6528530828655 -1258,1258,G90I,0.002888562,-0.064936436,-0.026845417000000003,0.013477233,-0.13522483300000002,0.021733745,0.039848469,-0.034071346,0.013850265,-0.037380698,-0.09249217300000001,-0.002474619,-0.051216214,0.011964383,0.014990082,-0.097576952,-0.172872713,1.307517609,2.2875449690000003,-4.439312163,-3.4452963710000004,-4.549177803,-5.130625496,-4.27754081,-4.793920334,-5.442943898999999,-3.5939823719999997,-1462.215950733982 -1259,1259,G90H,-0.035120017999999996,-0.00225988,-0.046302202,-0.022072485,-0.0363664,0.015426306,0.001165859,-0.071405895,-0.054758920999999995,0.087495374,-0.09201513300000001,-0.001142491,-0.09146191199999999,0.08802538800000001,-0.132170357,0.022700627,-0.095433426,1.161577178,2.80785781,-2.214704089,-2.184244568,-2.184709663,-2.9933678130000003,-1.3430709230000002,-2.36812748,-3.7010980630000003,-0.526488823,-1459.6196153517812 -1260,1260,G90K,-0.047787407999999996,-0.044188693,-0.07503638900000001,-0.026130331,-0.108828669,0.030080282000000003,-0.033801923,-0.061772892999999995,0.027623552000000003,0.003706253,-0.09208363800000001,-0.023993835,-0.126078942,0.029014982,-0.08127564400000001,-0.064238083,-0.153419254,1.3087248409999999,2.444385149,-1.029455095,-0.665827843,-1.022767685,-2.153696175,0.290692223,-1.595675995,-3.5614084160000004,-0.5242448670000001,-1457.9289904683828 -1261,1261,G90M,-0.077176066,0.020540893,-0.061032885,-0.03129388,-0.039755865,0.057239852,-0.059311494000000006,-0.095040637,-0.054770488,0.075723731,-0.034641946,-0.050641593,-0.07142417599999999,0.029923518,-0.09251127699999999,-0.028009742,-0.051501988,1.153119917,2.483269178,-3.380902838,-3.0960743789999996,-3.224320137,-4.339163193,-3.0489571989999997,-3.195999283,-4.6907080830000005,-2.197064398,-1462.5632721818984 -1262,1262,G90L,-0.022481755,-0.036988303,-0.045980277,-0.042022018,-0.128355617,-0.0026366209999999996,-0.019120553999999998,-0.025842955,-0.02504406,0.017058429,-0.091035034,-0.027581368,-0.06437918599999999,-0.008597776,-0.07544626,-0.08607041,-0.170640824,1.317843664,2.272856615,-3.6578066010000003,-3.357116364,-3.359164497,-4.359600189,-3.39148851,-3.821663445,-5.1270391239999995,-1.8401084069999998,-1460.2709243502468 -1263,1263,G90N,0.006343596999999999,0.030640358,-0.032043377000000005,-0.057378282,0.017350078999999997,0.031535966,0.06217728,-0.049490085999999996,-0.022617247000000004,0.083460573,-0.022179857,-0.019254799,-0.044831955,-0.07962124400000001,-0.035135319,0.024723835,0.009976322,1.246537915,2.6730107000000003,0.461524382,0.903820244,0.194623665,-0.936723015,2.509061478,-0.363160461,-1.174435143,1.098494901,-1462.4128579166718 -1264,1264,G90Q,0.017906928,-0.012561158000000001,-0.024980777000000003,0.001080846,0.072975398,-0.027823412999999998,0.030618935,0.00519492,-0.006817212,0.0055737980000000005,-0.030696114,0.008434617,-0.058396171,0.015396911999999999,-0.01323522,0.03720463,0.10874616599999999,1.144309066,2.690097492,-0.225791658,-0.060725449,-0.541879868,-0.766580666,0.317155289,-0.076927597,-2.9089692510000003,0.38408995,-1460.5221095602028 -1265,1265,G90P,-0.013313483999999999,-0.012883043,-0.053745142,-0.027673671,-0.68542057,0.069054024,0.012811323000000001,-0.039438291,-0.018589675,0.048545831,-0.07431191599999999,-0.051992995,-0.055497288,0.016172166,-0.071519508,-0.482410657,-0.8884304829999999,1.037036757,1.574487789,-3.999522859,-3.957960838,-4.067958153,-4.165689438,-3.940905617,-3.86510025,-4.870941022,-2.9248922530000003,-1459.9322116626427 -1266,1266,G90S,-0.024565003999999998,-0.007594556,-0.037740391,-0.036856002,-0.020904624,0.008073971,-0.01278993,-0.036340078,-0.025510036,0.011574067,-0.026763178999999998,-0.013209936,-0.062270846,0.010040401,-0.083752405,-0.028674188,-0.013135059,1.2058970359999999,2.468424679,1.199482962,1.618060768,1.671185806,0.663164131,1.086216354,0.95878775,-1.733391537,1.014104043,-1463.378094136715 -1267,1267,G90R,-0.011144793,-0.029979371,-0.027049356,-0.028472152999999997,-0.145842567,0.066396362,0.013568598999999999,-0.035858185,-0.047361484,0.00678143,-0.066740172,0.017705916000000002,-0.071804628,0.016812739,-0.073757045,-0.093500585,-0.198184549,1.4161064140000001,2.383663826,-2.3517706990000002,-2.787357956,-2.659085403,-2.551516113,-2.200635124,-1.560258896,-3.955069528,-0.129797563,-1456.591480373405 -1268,1268,G90T,-0.01367986,-0.009774634,-0.05549761,-0.014621773999999999,-0.032386576,0.027424319,0.015698497,-0.043058217,-0.0800005,0.007263375999999999,-0.026812644,-0.058674599,-0.05232062,0.02438371,-0.053627258,-0.002251031,-0.06252212,1.19982473,2.625129314,0.332218887,1.087582489,0.6897421420000001,-0.22915313699999998,-0.063707809,0.176630753,-1.7138391990000001,0.9082618809999999,-1462.576945417095 -1269,1269,G90W,0.031069977000000002,-0.06479175599999999,-0.115450201,-0.076960094,-0.044056476,-0.024997495,0.061015905999999995,0.001124048,-0.07213301700000001,-0.058971317,-0.070612194,-0.11281117,-0.11808923199999999,-0.00405294,-0.149867248,-0.032777291,-0.05533566,1.155281826,2.460090148,-5.044825684,-4.739189026,-4.707842316,-6.01606926,-4.563046707,-5.19798111,-5.574649302,-3.987336781,-1463.0104925753549 -1270,1270,G90V,-0.037485835,-0.00797489,-0.032687119,-0.022575779,-0.155368692,0.063601296,-0.033852512,-0.041119157999999996,-0.020487711999999998,0.03462074,-0.05057052,-0.051840005999999994,-0.013534231,-0.012513136000000001,-0.032638421,-0.093473901,-0.217263483,1.376014197,2.397550292,-4.381040456,-3.6923404539999995,-4.47302375,-4.822299583,-4.329286354,-4.588252136,-5.905766611000001,-3.691706707,-1462.4658680665307 -1271,1271,G90Y,0.045050518,-0.006018651999999999,-0.047921822,-0.026719792000000003,-0.065199464,-0.037243736,0.039923636,0.050177399000000004,-0.039058585,0.042216339000000005,-0.054253643,-0.061164007,-0.034679637,-0.029768751,-0.023670832000000003,-0.091118209,-0.039280718,1.364757095,2.331489033,-3.110277296,-2.272916641,-2.363801697,-4.371236641,-2.830959908,-3.7124715960000003,-3.802099989,-1.97873753,-1460.7940387227573 -1272,1272,R91A,-0.00967035,0.05578526599999999,0.006254716,0.017544558999999998,-1.352936045,0.016006488,-0.019793734,0.000453035,-0.023253102,0.076339739,0.035230792999999996,0.027031401,-0.01452197,0.060408820999999994,-0.025319703,-1.07582265,-1.630049439,0.644716279,1.342459752,-5.840380174,-4.655249939,-7.064129157999999,-6.452024155,-5.65620504,-5.37429258,-4.3619854469999995,-1.4062586419999998,-1452.0254719699733 -1273,1273,R91C,-0.028013412,0.029660241,-0.163516514,-1.296169983,-1.363640025,0.058398075,0.002028667,-0.05805549,0.074262809,0.051148858,0.008171623000000001,0.055925055,-0.38295808299999995,-1.0698164959999998,-1.52252347,-1.69776873,-1.02951132,2.7728579539999996,2.077546304,-10.27884372,-9.07363279,-11.05307439,-11.00135783,-9.738714118999999,-10.52743948,-7.7328675229999995,-5.4305773010000005,-1456.1536744879559 -1274,1274,R91E,-0.023438773,0.064751486,0.059554225,-0.017830672,-1.8431241630000001,-0.006955819,0.004490597,-0.051368143,-0.039733244,0.076561144,0.052941827999999996,0.053459409000000006,0.06564904099999999,0.052639222,-0.088300565,-1.528472829,-2.157775497,0.664844662,1.317157412,-5.615023412,-4.520169151,-5.895663811,-6.016223198,-4.86084845,-6.782212447999999,-4.350516488999999,0.055298162000000005,-1447.4751122756861 -1275,1275,R91D,-0.09011313300000001,0.054419126,0.028988269,-0.135003069,-1.653138449,0.012118761,-0.069764831,-0.110461434,0.032807231,-0.010537709,0.11937596,0.018791045,0.039185492999999995,-0.021384847999999998,-0.248621289,-1.434527295,-1.871749602,0.753720389,1.328321211,-4.667224915,-3.033386932,-5.960324432,-5.854367927999999,-3.541084572,-4.946960709,-3.334611166,-0.21515210899999998,-1441.404935956467 -1276,1276,R91G,-0.036362733,0.02729582,-0.004293671,-0.843676104,-1.8398286419999998,-0.014140811999999999,-0.0077930840000000005,-0.064932381,0.01458025,0.024852125,0.029739513999999998,-0.021342929,0.012755586999999999,-0.5320690610000001,-1.155283146,-1.757597681,-1.9220596030000001,1.8009588380000001,1.478660284,-8.603991108999999,-7.6487215729999996,-9.472006805,-9.429393639,-7.880559578,-8.589273948999999,-6.567185891,-3.550973145,-1450.6368889422156 -1277,1277,R91F,-0.033950647,0.066268207,-0.029661079,-0.154379854,-2.190379396,-0.049434724000000006,-0.042734833,-0.02516646,0.086840222,0.053007135999999996,0.079529278,-0.065033942,0.005711785,-0.105320679,-0.203439029,-1.9726460069999998,-2.408112784,1.003704556,1.30917829,-11.84216129,-9.664563507,-11.35103831,-12.773514500000001,-11.75563979,-13.66605032,-8.19478142,-5.921714764,-1450.1110997321084 -1278,1278,R91I,-0.056227788,0.003949605,0.003976111,-1.342748218,-1.776368346,0.037391957,-0.063466133,-0.048989443,0.0013740129999999999,-0.015288745,0.023187955,-0.032830677999999995,0.040782900000000004,-1.058869316,-1.6266271190000001,-1.7116451330000002,-1.841091558,3.43709409,2.683243196,-10.01708651,-9.062224045,-11.20580643,-10.34726086,-9.367227837,-10.10291337,-7.553228699,-5.36454876,-1452.1573029300198 -1279,1279,R91H,-0.002327235,0.050562125,0.008185056,-0.041614867,-0.08997326900000001,-0.000980151,-0.03265535,0.028000881000000002,0.017979765,0.013219635,0.087904614,-0.04529347400000001,0.061663586,-0.039542033,-0.043687699999999996,-0.123303385,-0.056643152999999995,1.326909262,2.244538031,-5.355508748,-5.162794487,-5.642671668999999,-5.948014999,-5.081060905,-4.943001678,-5.190025438999999,-2.6468990519999998,-1453.5425900947303 -1280,1280,R91K,-0.016886984,0.030871008999999998,0.044181244,-0.008050241999999999,-0.12475316199999999,0.002753525,-0.026741721,-0.007032246999999999,0.011060307,0.042053352999999995,0.019688665,0.044154835999999996,0.044207650999999994,0.00312702,-0.019227503,-0.060279,-0.18922732399999997,1.543610422,3.106887046,-4.997492682,-3.966701485,-5.2420356980000005,-5.305514763,-4.398279778,-6.074931686,-4.077314994,-0.961435268,-1455.3127740914933 -1281,1281,R91M,0.016601234,0.004205370999999999,-0.001891278,0.048651268,-1.473200085,-0.001097249,0.02318271,0.010019756999999999,-0.048839022,-0.014966017,0.023376759,-0.053902752000000005,0.050120196,0.050901743,0.046400792999999996,-1.50294877,-1.443451399,0.660407842,1.3186029609999999,-8.425528963,-7.51768515,-8.804548561,-8.749572639,-8.160226219,-8.895612244,-5.903176602,-3.663119131,-1454.4334662454203 -1282,1282,R91L,-0.040372273,0.034529846,-0.018983322,-0.356925079,-1.701135439,0.033695024,-0.000366401,-0.080378145,-0.025442076,0.008720858,0.060338834,-0.022526504,-0.01544014,-0.155890262,-0.5579598960000001,-1.6436348269999999,-1.75863605,1.1087180429999999,1.349132705,-8.544838103,-8.215568665,-7.8623594279999995,-9.440935248999999,-7.895217545,-9.310109627000001,-6.344775847,-4.051053959,-1453.2609487418085 -1283,1283,R91N,0.024183516000000002,0.065282619,0.003236394,0.043835618,-0.512989782,-0.010320457,0.0042813320000000005,0.044085699000000006,-0.027981381,0.015579981000000001,0.114985257,0.0049869070000000005,0.00148588,0.054458365,0.03321287,-0.39134962700000003,-0.6346299360000001,0.959204707,1.594013465,-6.664937654,-5.698930054,-8.23853019,-6.923328285,-5.965567711,-6.498332031,-4.759600775,-3.439779182,-1448.4038732992485 -1284,1284,R91Q,0.003279587,0.076524345,0.018904481,0.060764535999999994,-1.3668792369999998,0.04569659400000001,0.041986792,-0.035427619,0.039561558,0.081928661,0.071120028,0.046292977,-0.008484015,0.075508883,0.046020189,-1.177311635,-1.5564468390000001,0.662049847,1.3370498990000002,-4.460664192,-3.8052919160000003,-4.983805611,-4.035660782,-4.186394241,-5.2921684110000005,-3.813614832,-0.02630033,-1455.6409556982107 -1285,1285,R91P,-0.019689701,-0.351512703,-1.684834607,-2.050477453,-2.571355016,-0.061552024000000004,-0.012371756999999999,-0.027007644,0.012672393999999998,-0.24321341300000002,-0.459811993,-1.5955793180000002,-1.774089896,-2.07113481,-2.029820096,-2.396087455,-2.7466225769999997,1.215644032,0.07561198200000001,-11.09000541,-9.916807327,-12.15708882,-11.97887112,-10.427356,-10.96990378,-9.409700667000001,-8.783288814,-1455.36337666912 -1286,1286,R91S,-0.05486617,0.034438365,-0.01879807,0.006838716,-1.3524947180000002,0.059137029,-0.044184738,-0.065547601,-0.02003438,0.003832443,0.065044287,-0.012678143000000001,-0.024917996,0.024023182,-0.01034575,-1.372534984,-1.332454451,0.46696642899999996,1.312525447,-5.9304858629999995,-5.694097954,-6.636045403,-7.008242111,-5.538773262,-4.775270583999999,-4.933649994,-1.671240351,-1448.9654930830002 -1287,1287,R91T,0.006034024,0.016851294,-0.0012853,0.011774613,-0.598956526,0.000731268,-0.010634444,0.022702492,-0.00866148,0.040466962999999995,-0.006764376,0.00969554,-0.012266138999999999,0.029292285,-0.00574306,-0.47913618799999996,-0.7187768640000001,0.388446809,1.377261345,-5.215698592,-4.495002243,-5.708961456,-5.846373665,-5.148950684,-4.87920491,-4.407822191,-0.8665416359999999,-1449.8019482800737 -1288,1288,R91W,-0.050481585999999995,0.069254133,-0.003473855,-1.250980008,-2.215240255,0.008275399000000001,-0.018429021,-0.08253415,-0.041056143999999996,0.146873801,-0.008365536,0.022894148,-0.029841857000000003,-0.837313119,-1.664646897,-1.7277319530000002,-2.702748557,2.332359363,1.762587074,-10.62294972,-9.998049957000001,-11.03666017,-11.18492781,-10.45752449,-10.43758615,-8.710030576,-7.207296212999999,-1452.753132931888 -1289,1289,R91V,-0.018346995,0.027888465,-0.012152521999999999,-0.5130226689999999,-1.920734529,0.07378203,0.009377406999999999,-0.046071395999999994,-0.078731592,-0.019696836000000002,0.075473766,-0.053851834,0.029546791,-0.294613795,-0.731431543,-1.866273866,-1.975195192,1.4228090359999999,1.362824807,-9.823598924,-8.5694944,-11.25666138,-10.21012211,-9.235946739,-9.845769997,-7.585390583,-5.256167918,-1453.3499157303013 -1290,1290,R91Y,-0.070865199,0.10684439800000001,-0.0077400659999999994,-0.019365663999999998,-2.267574631,0.038788245,0.016376676,-0.15810707400000001,0.065765512,0.07733138,0.136357416,0.025427923999999998,-0.040908056,0.000534427,-0.039265754,-1.7861349690000001,-2.749014292,0.737933925,1.308669763,-11.51182513,-10.555996400000002,-12.44442852,-11.79199636,-11.22773044,-11.53897393,-7.9974354729999995,-5.981887541,-1449.7623206530698 -1291,1291,R92A,0.026271627999999998,0.019577266,0.009473914,-0.053823062000000005,-0.617133217,-0.019135413,0.002922575,0.04962068099999999,-0.054635715999999994,-0.025488952999999998,0.064643485,0.005147109,0.013800718,-0.064472997,-0.043173126,-0.434919922,-0.7993465120000001,1.34391434,1.7868211880000002,-3.984273944,-3.516363075,-4.365804031000001,-4.978966225,-4.130205353,-2.9300310360000004,-4.83048032,-2.192383569,-1459.485403554514 -1292,1292,R92C,0.018251484,0.06336801,0.07450053400000001,-0.067920639,-1.457742572,-0.024893836000000003,-0.0036579959999999997,0.040160963,-0.049334907000000004,0.045328405,0.081407614,0.08109888700000001,0.06790218099999999,0.028657282000000003,-0.16449855900000002,-1.327608473,-1.5878766709999999,0.640356936,1.3264569179999999,-7.368115352,-6.548204544,-8.479263367,-7.795987244,-8.108190628,-5.908930977000001,-7.561589766,-4.956647049,-1461.4420701637864 -1293,1293,R92E,-0.039345628,0.00232509,-0.008034666999999999,-0.016457714,-0.591414856,-0.0056637630000000005,-0.034427252,-0.044264002999999996,-0.088363019,0.010561055,-0.005910876,0.047788597,-0.06385793,-0.016425508999999998,-0.016489919,-0.308839911,-0.8739898009999999,1.624941907,2.169335106,-5.250857617,-5.028100693,-6.579368011000001,-5.674376732000001,-6.183623299,-2.7888193510000003,-4.740956027,-1.552171489,-1458.8246118291281 -1294,1294,R92D,0.00152879,0.051200138,0.05550978,-0.061650037000000005,-1.554089535,-0.039839619,-0.012437256,0.015494836000000001,-0.119771065,0.064008988,0.038391287,0.0743175,0.03670206,0.046782711,-0.170082785,-1.569075835,-1.5391032340000002,0.574707504,1.311379929,-7.269385872999999,-6.737715439,-8.236469223,-7.871647652,-7.530812263,-5.97028479,-7.172757021000001,-4.434305125,-1458.30082106404 -1295,1295,R92G,0.01619548,0.019031882,0.012819025,-0.08704626300000001,-1.714960669,-0.060118520999999994,-0.002349509,0.034740468,-0.049294240999999996,0.020668392,0.017395372,-0.0041604979999999995,0.029798547,-0.012189748,-0.161902777,-1.68155848,-1.7483628569999998,0.596479557,1.307477768,-6.51556158,-5.90240667,-7.291848145,-7.260743431,-7.062835982999999,-5.059973671,-6.637216627000001,-4.118027833,-1455.4827119624242 -1296,1296,R92F,-0.054596324,0.030921571000000002,-0.007493579,-0.052940994000000005,-0.302908098,-0.009861701,-0.09796576300000001,-0.011226885,-0.10061373300000001,0.005772436999999999,0.056070704000000006,-0.001364175,-0.013622981999999999,-0.0023310270000000003,-0.10355096,-0.195704018,-0.410112177,1.081654945,1.8600571,-5.891791014,-5.904228653,-7.2565380710000005,-6.277097457999999,-5.777193405,-4.243897484,-5.54054542,-4.0964100519999995,-1466.4753694436513 -1297,1297,R92I,0.000744773,-0.009399505,0.063025905,-0.015121806000000002,-0.036945939,-0.0951893,-0.092134099,0.093623645,-0.058526966,-0.022507925,0.003708915,0.065337087,0.060714723,0.00679796,-0.037041571,0.020260078,-0.094151955,1.069686565,2.61208164,-4.672584721000001,-4.742434875,-6.666088318,-4.353712654,-4.8020123439999995,-2.798675415,-4.944547964,-2.1760084930000003,-1469.4418772999197 -1298,1298,R92H,0.031071084,0.11987474099999999,0.024042967999999998,-0.028964305,-0.103741082,-0.036856112999999996,0.03264855,0.029493618,-0.10029551800000001,0.033087198,0.206662283,0.009694169,0.038391766,0.002241957,-0.060170567,-0.13532386300000002,-0.072158301,1.5268203619999998,2.38409496,-3.53959453,-3.4944493939999997,-3.941037521,-4.222607826,-2.910080002,-3.129797905,-4.970139946000001,-2.9812249210000004,-1462.49208428571 -1299,1299,R92K,0.058331875,0.09893235199999999,0.049226232,0.047867058,0.025212107,0.004889773,0.055693550999999994,0.060970197999999996,-0.077911211,0.089501311,0.10836339199999999,0.044465221,0.053987242000000005,0.049606012000000005,0.046128103,0.08505002199999999,-0.034625808,1.085829812,2.977637993,-3.1890761110000003,-2.8451103360000003,-3.758185371,-3.721832352,-3.80005986,-1.820192635,-4.063320022,-0.712624122,-1460.877003843896 -1300,1300,R92M,-0.016017454,-0.00151728,0.008420658000000001,-0.051829907,-0.042024153,-0.09005054400000001,-0.068806412,0.036771505,-0.012782756000000001,-0.027071481,0.024036921,0.045946767,-0.029105452,-0.005988023,-0.09767179,0.023790826,-0.10783913199999999,1.229112177,2.776510943,-5.058031693,-4.600204323,-6.992193695,-5.670878448,-5.464441902000001,-2.5624400940000003,-5.573532002,-2.0785086759999998,-1474.1071436116472 -1301,1301,R92L,0.002988863,0.033411067,0.005582826999999999,-0.025985269,-0.044805637,-0.06161556,0.000854523,0.005123202,-0.045036346,0.01217925,0.054642882999999996,0.018211585,-0.007045931,-0.006188931,-0.045781607,-0.026007317999999998,-0.063603956,1.671448915,3.643209181,-4.618163457,-3.81513678,-6.296243782,-5.323698936,-4.631976997,-3.023760788,-4.7954005969999995,-1.722096549,-1468.5832542199641 -1302,1302,R92N,0.023811185,0.057440782,0.009103993000000001,-0.000378256,-0.266378004,-0.003606916,0.005327039,0.042295331,-0.082965768,0.035128873,0.07975269,0.046974003,-0.028766017,0.005462574,-0.0062190859999999995,-0.177220612,-0.355535396,1.355919774,2.133455404,-5.694545617999999,-5.071522301,-6.983017464,-6.647480461000001,-5.516918251,-4.253789612,-5.982278946,-3.156443377,-1458.5420709089376 -1303,1303,R92Q,0.05295647,0.035158665,0.028091881000000003,0.023782552999999998,-0.112583396,0.001161048,0.027516227,0.07839671299999999,0.001346553,0.011537368000000001,0.058779962000000005,0.023719814,0.032463947,0.008355141,0.039209965,-0.04915913400000001,-0.17600765699999998,1.3068407,2.527913776,-4.054557207,-3.416456375,-5.473992546,-4.224748161,-4.097145248,-3.0604437030000002,-5.111399461,-1.605470049,-1460.781778297387 -1304,1304,R92P,0.027726756,0.071519341,0.047272540999999994,0.017053733999999997,-0.997423642,0.00615767,0.004836391,0.050617120999999994,-0.084588705,0.022100218999999997,0.12093846300000001,0.039957345,0.054587736,0.0062435,0.027863968,-0.738292352,-1.256554932,0.7690083529999999,1.40133507,-3.6754997439999997,-3.283137505,-3.3930104219999997,-5.374421196,-4.587670692,-1.7392589040000002,-4.5318925089999995,-0.947335783,-1458.0740068885498 -1305,1305,R92S,0.033265449,0.050078673,0.01158973,-0.022563182,-0.379494693,-0.006331725,0.019463649,0.047067249000000005,0.014575487,-0.013259276,0.113416622,-0.01731329,0.040492749,-0.039427722000000005,-0.005698641999999999,-0.28136355399999996,-0.477625831,1.326018949,1.9126040069999999,-3.744684401,-2.771876694,-4.623070885,-5.446083412,-3.1413031080000002,-2.741087906,-4.426371704,-1.552332475,-1456.9381143311039 -1306,1306,R92T,0.008648039,0.040669226,0.022357452000000003,-0.030511688,-0.029915213,-0.090280131,-0.050383826,0.067679903,-0.019934973,0.033441198,0.047897253,0.067260615,-0.022545711,-0.016070838,-0.044952537,0.016771794,-0.076602219,1.172144321,2.639365773,-3.4888100860000004,-3.048537949,-4.304962959,-4.590287238999999,-3.1212321089999997,-2.379030174,-3.586286846,-1.08204136,-1459.9880623044446 -1307,1307,R92W,0.022277446,-0.023962126,0.035816508,0.006838099,-0.434074301,0.01997028,0.034214989,0.010339902,-0.071046132,-0.049432857000000004,0.001508605,0.053167385,0.01846563,0.009580414,0.004095784,-0.278668812,-0.58947979,1.107573596,1.774359031,-6.833058815,-6.583540245,-7.633850197,-7.16811515,-7.157276955,-5.6225115279999995,-7.058713057,-5.149445707,-1461.4016038398258 -1308,1308,R92V,0.021690624,0.030863001,0.03761103,-0.038880752000000005,-0.051775185,-0.049594440999999996,0.002897334,0.040483913999999996,-0.026783092,-0.017132959,0.07885896099999999,0.022226976000000002,0.052995084000000005,-0.00845658,-0.069304923,0.000861334,-0.10441170400000001,1.231685683,2.676286906,-3.573799747,-3.674527771,-5.340761734,-2.70908857,-4.0202420960000005,-2.124378563,-4.032084053999999,-0.911518376,-1468.89710954763 -1309,1309,R92Y,0.12528215,0.139720665,0.133774451,0.020753554,-0.049946375,-0.034055132,0.048149711,0.20241458899999998,0.033979814,0.05400671,0.22543462,0.113645533,0.153903369,0.010916165,0.030590943,-0.096883039,-0.00300971,1.122556846,2.1778621719999998,-6.487003258,-6.143374832,-8.037272881,-6.655966857999999,-7.161269676,-4.437132042,-7.65887629,-4.79215794,-1460.290674943477 -1310,1310,I93A,0.061037032000000005,0.10923835800000001,0.095648303,-1.266763837,-1.960784664,0.080064377,0.09714996099999999,0.024924103,-0.08628753300000001,0.130303996,0.08817272,0.048357200999999995,0.142939405,-1.168394752,-1.3651329209999998,-1.7291740230000001,-2.192395304,3.0066701989999998,2.242778209,-6.438436014,-6.421102303,-6.4257481,-5.975035736000001,-8.096242683,-5.274051247,-5.419369782,-3.7856560760000004,-1448.3991115982644 -1311,1311,I93C,-0.08862582,0.026995981000000002,0.040232869,-0.610789686,-2.445633448,0.29642875399999996,-0.045889663,-0.131361977,-0.041324726,0.08982659,-0.035834628,0.131420864,-0.050955125999999996,-0.301616032,-0.919963339,-2.17091332,-2.720353575,1.255544213,1.307548263,-9.52363549,-9.459982101,-9.218260772999999,-11.10804194,-9.790346176,-8.041546463,-8.0455945,-6.027269829,-1450.9275838490576 -1312,1312,I93E,0.072400746,0.06856923200000001,0.077051975,-1.162497981,-2.328514781,0.09694108,0.10010451,0.044696981,-0.058727919,0.092668185,0.044470277999999995,0.02165553,0.13244842,-0.9904019409999999,-1.334594021,-1.974783212,-2.682246349,2.198145596,1.546592358,-8.761174513,-8.320303711000001,-8.554023642999999,-9.523994415,-10.01853043,-7.38902037,-6.59492293,-5.522805684,-1460.4680162505247 -1313,1313,I93D,0.028726936,0.01416216,-1.377755769,-2.2626174519999998,-2.531716041,0.110353058,0.084568141,-0.027114269,-0.139577949,0.004039978,0.024284341,-1.465437934,-1.290073603,-2.439537364,-2.085697539,-2.15047216,-2.9129599219999998,0.625080795,0.040648933,-11.52578346,-11.55407478,-11.22533471,-12.99248003,-12.30706837,-9.549959427000001,-9.516183876,-9.435356602999999,-1461.0795544860885 -1314,1314,I93G,-0.004848768,-0.022762212,-1.229219581,-2.067411457,-2.332829497,0.136786919,0.03135761,-0.041055145,-0.050965399,0.040220707,-0.08574513,-1.282531815,-1.175907347,-2.148848201,-1.985974712,-2.429658306,-2.2360006869999998,0.5567988460000001,0.06545246,-10.77337692,-10.97244062,-10.52698385,-11.06027406,-11.81401947,-9.493166602999999,-9.255026632,-8.254351544,-1452.9432411133312 -1315,1315,I93F,-0.011748797,0.013327,0.033332611,-0.12712098900000002,-1.9054200190000001,0.09633873800000001,0.009264731,-0.032762325,-0.073932492,0.142342676,-0.11568867699999999,0.085663374,-0.018998153,-0.022148717000000002,-0.23209326,-1.43551405,-2.375325988,0.463041086,1.311064338,-6.452957467999999,-6.4207013239999995,-6.200675446,-9.425014885,-5.428243149,-4.790152534,-6.042227499,-2.775048522,-1446.6331254923716 -1316,1316,I93H,0.045519467,0.11434024400000001,0.007659686999999999,-0.719483179,-1.8746203209999999,0.112818824,0.111875184,-0.020836251,-0.08040633700000001,0.131358416,0.097322072,-0.071745673,0.087065046,-0.327212319,-1.111754039,-2.19043546,-1.5588051809999999,1.381604574,1.307700142,-9.286875352000001,-9.930239143,-8.664343536,-11.59463589,-8.737560692,-7.507597504,-7.022177961000001,-3.551168362,-1455.3355238060467 -1317,1317,I93K,0.0067833680000000006,0.103103494,0.074804032,-1.603699318,-2.628070413,0.07130597400000001,0.047476304000000004,-0.033909569,-0.038375831,0.132706587,0.07350040099999999,0.073856583,0.075751481,-1.329644755,-1.87775388,-2.295852057,-2.9602887680000003,0.76053415,0.723942538,-8.768377151000001,-8.875477242,-8.32100502,-9.003940361,-9.541783668999999,-8.099679466,-7.201274764,-5.522805716000001,-1456.1988647868857 -1318,1318,I93M,0.03931536,0.053784667,0.060687749000000006,0.011312835,-0.198821455,0.117997346,0.050258432,0.028372287000000003,0.042085322,0.078033344,0.029535989,-0.024904236,0.146279734,-0.06331343099999999,0.08593910099999999,-0.219405253,-0.178237657,1.472246367,2.14117482,-4.558236092,-4.447794334,-4.453969528,-5.228156578,-4.443018257,-4.21824176,-5.106339411,-2.9185400789999996,-1451.1675236988813 -1319,1319,I93L,0.063543481,0.068265429,0.056439040999999995,-0.018117044,0.009083016999999999,0.039754894,0.068267908,0.058819052999999996,-0.03133549,0.097250799,0.039280058,-0.003007744,0.115885825,-0.093452089,0.057218001,-0.027125582999999998,0.045291617,1.338492354,2.571581711,-2.98749124,-2.894065186,-2.585184685,-4.239575188,-2.60090744,-2.617723701,-3.466693802,-0.5822785189999999,-1450.55644014664 -1320,1320,I93N,0.108282202,0.146553253,-0.043318315999999996,-1.5634569040000001,-1.829985674,-0.000315506,0.112799543,0.10376486,-0.092124879,0.175722118,0.117384388,0.0038420309999999997,-0.09047866199999999,-1.737943215,-1.388970592,-2.227029262,-1.432942085,-0.170565839,0.668172263,-9.981471383999999,-10.30947153,-9.896378754,-11.26279074,-10.42028214,-8.018433762,-7.921620836000001,-6.027269842999999,-1459.8530189292505 -1321,1321,I93Q,0.01416945,0.057008333,0.077859708,-0.313567194,-1.654153896,0.074734333,0.028830527,-0.000491628,-0.085356921,0.11078349400000001,0.0032331720000000003,0.048778025,0.106941391,-0.22275721899999998,-0.40437716799999995,-1.8715441080000002,-1.4367636830000001,1.1336854090000001,1.327333361,-9.09600806,-8.681132202,-8.67726754,-10.04222624,-9.799269942999999,-8.280144371,-6.8069016410000005,-5.503169431,-1453.4841628144495 -1322,1322,I93P,0.040158812,0.088148172,-0.890884166,-1.716071084,-2.827592355,0.168781199,0.086552354,-0.006234730999999999,-0.082824393,0.064160244,0.11213610000000002,-0.848203376,-0.9335649559999999,-1.5378720730000002,-1.894270095,-2.59122955,-3.063955159,2.333422203,1.198497118,-10.37183423,-10.59605161,-10.01594638,-11.26768307,-10.9713285,-9.008161583,-8.530182233,-6.959227195,-1458.1274277740158 -1323,1323,I93S,0.00228312,0.052066459,-0.137030074,-1.547728334,-2.278966567,0.07369431,0.028544795,-0.023978555,-0.03053551,0.066374037,0.03775888,-0.068640522,-0.20541962600000002,-1.456917159,-1.638539508,-2.122094465,-2.435838668,1.366828481,0.7874784459999999,-8.013927866,-7.815535835,-8.566603958,-8.054255066,-9.783204269,-5.8500401989999995,-6.752208475,-5.511046595,-1457.0134424404241 -1324,1324,I93R,0.027995575,0.057986145,-0.044404622000000005,-1.508261534,-2.473268585,0.141295561,0.076347862,-0.020356712,-0.048621954,0.083482926,0.032489363,-0.031063759,-0.057745485,-1.43067549,-1.585847578,-2.372059207,-2.574477963,0.867607538,0.722918527,-8.680274438,-9.236244316,-7.7256719060000005,-9.846821228,-8.778345512000001,-7.81428923,-6.295281675,-3.772880839,-1449.8990048756823 -1325,1325,I93T,0.056943104,0.077423485,0.055443864,-0.68674362,-1.958171757,0.058535812,0.107611581,0.006274627,-0.12835033699999998,0.07354295200000001,0.081304017,-0.00295154,0.113839267,-0.40184751700000004,-0.971639722,-1.770111393,-2.146232121,1.5816353330000001,1.4128870359999999,-5.857366466,-5.74448484,-6.051652214,-5.074427765,-7.918670326,-4.497597183,-5.00545612,-3.518235515,-1453.4201209601015 -1326,1326,I93W,0.017348563,0.048124676,0.04764816400000001,-1.3505065330000001,-2.628955372,0.008206831,0.055587665999999994,-0.020890541000000002,-0.069299268,0.08245324,0.013796111000000002,0.015292881000000001,0.080003447,-1.415943206,-1.285069859,-2.683180503,-2.57473024,0.6345527879999999,0.707012973,-9.209098218,-9.214653893,-8.855229117999999,-11.46576144,-8.917599518,-7.592247116,-7.201778448,-4.9881197230000005,-1452.2471817079931 -1327,1327,I93V,0.064060271,0.069159089,0.05623637099999999,0.013388793000000001,0.051135263,0.087801151,0.070496317,0.057624224,-0.11981775900000001,0.077962296,0.06035588099999999,0.026154548,0.086318194,-0.062788396,0.08956598199999999,-0.013923323999999999,0.116193849,1.1590111090000002,2.468212931,-1.252095132,-1.166196327,-1.046139633,-1.506374168,-1.791257851,-0.7505076829999999,-3.091617779,0.041563895,-1451.4539201487787 -1328,1328,I93Y,0.014565831000000001,0.10875777699999999,0.040259686,-0.010597841,-1.934341136,0.090951722,-0.016730135,0.045861797,-0.135489231,0.083951745,0.133563808,-0.048636582000000005,0.12915595400000002,-0.021939872000000003,0.00074419,-1.2727867529999999,-2.595895519,0.659395373,1.330672208,-8.123172527000001,-8.55922361,-7.811484397999999,-11.64892598,-6.618354515,-5.97787413,-6.369696619,-2.334561872,-1447.6316388780251 -1329,1329,H94A,0.008190886999999999,-0.020863358999999998,0.006116085,-0.035357604,-0.08015141,0.024509881,0.006654876999999999,0.009726896,0.006926339,-0.066661521,0.024934803999999998,-0.050348388,0.062580557,-0.035545391,-0.035169817,-0.138987189,-0.021315631,1.271341103,2.12557449,0.047161813,0.292483521,-0.669142799,0.022370888,-0.738123199,1.3282206570000001,-2.070580143,-0.28510435100000003,-1451.1826655911282 -1330,1330,H94C,-0.0062728459999999995,-0.038981483,-0.01146102,-0.01472634,-1.083906813,0.10447131,0.027173059,-0.03971875,-0.005016273,-0.033550259,-0.044412705999999996,-0.069788868,0.046866828,-0.022917418,-0.006535261999999999,-0.94034963,-1.227463995,0.86562072,1.389362405,-3.5628570789999996,-3.4369661639999998,-3.721215935,-4.193056969,-3.7597175519999997,-2.7033287739999996,-5.498467096000001,-3.609585763,-1453.783048641868 -1331,1331,H94E,0.040966153,-0.001807475,-0.038732702,-0.004739744000000001,-0.062243135,-0.071911772,0.031963845,0.04996846,-0.022360038,-0.040554013,0.036939063,-0.086107606,0.008642203000000001,-0.036395111,0.026915624,-0.09321819099999999,-0.031268078,1.315768198,2.266309884,-0.292440047,0.026749672000000002,-0.9881182479999999,-0.809830536,-0.901876083,1.210874962,-2.8642833710000004,-0.327817181,-1451.5741934739053 -1332,1332,H94D,0.041547262,-0.02301181,0.000617414,-0.053304147,-0.218190842,0.061392477,0.040862874,0.042231649,-0.007345121,-0.113894275,0.067870655,-0.070951638,0.072186465,-0.112196537,0.0055882430000000006,-0.28989363,-0.146488054,1.5302206180000002,2.062997791,-1.665114725,-1.661470276,-2.845548897,-1.6289506,-2.458661949,0.269058098,-3.660682385,-1.427719265,-1449.6849238378927 -1333,1333,H94G,0.032364871,-0.026073076,-0.006642724,-0.032364749,-0.283787057,0.022033719,0.047526147000000005,0.017203595,-0.011402526000000001,-0.030579997,-0.021566154,-0.055186444,0.041900997,-0.062420144000000004,-0.002309353,-0.276372923,-0.29120119,1.597199518,2.143681705,-1.436057375,-1.62010498,-2.0999814530000003,-0.73204657,-2.582020714,-0.146133156,-3.0300912710000003,-2.375201654,-1454.749023245182 -1334,1334,H94F,0.037794486,-0.033495889,-0.012454825,-0.004578771,-0.050553047999999996,0.0018111610000000002,0.022443431,0.053145541,-0.012194343,-0.072943816,0.005952038000000001,-0.072350848,0.047441198,-0.034031106,0.024873565,-0.12200838,0.020902285,1.286626118,2.174956232,-2.283855458,-2.1753368230000003,-2.965018158,-2.653693199,-1.467953545,-2.157275566,-4.04540057,-0.9992813979999999,-1456.8381419233046 -1335,1335,H94I,0.023113707999999997,-0.082947921,-0.045549782000000004,-0.032439172999999995,-0.073751089,-0.051684783,0.022116369,0.024111047000000004,-0.001645049,-0.0684182,-0.09747764099999999,-0.042508902,-0.048590662,-0.064440235,-0.000438111,-0.097129853,-0.050372324,1.3582868559999999,2.328034385,-1.350378624,-1.012150055,-1.150470863,-2.0996764530000003,-1.955564606,-0.534031143,-3.387062826,-0.9601009,-1447.2048644721508 -1336,1336,H94K,0.063329593,-0.028654479,-0.022433307000000003,-0.0051524529999999995,0.006742309,-0.029457987999999997,0.049769602,0.076889584,-0.011331303000000001,-0.079263045,0.021954087999999997,-0.082003335,0.037136721,-0.042852363,0.032547457,-0.044049492999999995,0.057534111,1.377425088,2.400084896,0.6206935029999999,0.740410751,1.2992620240000001,0.302712112,-0.6276424939999999,1.388725121,-1.049212673,-0.504089911,-1457.9773467960767 -1337,1337,H94M,0.092507305,-0.049155555,0.040542876,0.012545546000000001,-0.035634476,-0.047752776,0.094126654,0.090887955,-0.018930008999999998,-0.074330682,-0.023980427000000002,-0.062272497,0.143358249,-0.056641755,0.081732846,-0.10421939,0.032950438,1.2749308609999999,2.193197056,-1.20655701,-1.340002357,-1.081312401,-1.420315895,-1.66887516,-0.522279236,-2.72030051,-2.029179644,-1451.8632180956192 -1338,1338,H94L,0.041418817999999996,-0.021860262999999998,0.019448253999999998,0.014861906000000001,-0.031465014,-0.019384134,0.041373533,0.041464102999999995,0.051710045999999996,-0.015151543,-0.028568982000000003,-0.02530835,0.064204857,-0.002358339,0.032082151,-0.04215052,-0.020779508000000002,1.312288508,2.527666673,-0.583149619,-0.733327728,-0.729720123,-1.2564071959999998,-0.41727338399999997,0.220980339,-2.404641127,-0.456164521,-1446.2005436494946 -1339,1339,H94N,0.04967761,-0.06463203599999999,-0.019856274,-0.034212868,-0.121656165,-0.020537062,0.06190845,0.037446769,-0.027623991,-0.082529514,-0.046734557999999995,-0.091712368,0.051999820999999995,-0.095499939,0.027074203999999998,-0.132913618,-0.110398711,1.496222659,2.296015638,-1.5956077480000002,-1.595626671,-1.6900335690000001,-1.644319237,-2.246903191,-0.801156075,-3.0831086869999997,-2.30969854,-1456.9410006520338 -1340,1340,H94Q,0.026126791,0.01638219,-0.0068709190000000005,0.027865102000000003,-0.014702428,0.028827756,0.037893718,0.014359863,0.076341206,-0.046058588,0.078822968,-0.043849414,0.030107577000000003,0.002618206,0.053111998,-0.078093573,0.048688718,1.261419158,2.299702064,-0.001219711,0.253184029,0.492977051,-0.359717712,-0.866521164,0.47397924,-1.754796976,-1.4163905069999998,-1456.3998093493283 -1341,1341,H94P,0.012941107,-0.032037707,-0.027974991,-0.030031462000000002,-0.530404004,-0.030228652,0.036896754,-0.01101454,-0.033298468,-0.053529065,-0.010546348999999998,-0.07458868,0.018638698999999998,-0.046142717,-0.013920206999999999,-0.470286975,-0.5905210329999999,1.403902652,1.78580415,0.326791032,0.735918167,0.166367188,-0.587603119,-0.436643021,1.7559159469999999,-2.248804732,0.27320843,-1445.6287699211389 -1342,1342,H94S,0.061998537,-0.016005265,0.031098896,-0.0013455989999999998,-0.055668842,-0.010948113,0.07695727200000001,0.047039802,0.0054464859999999995,-0.027944637999999997,-0.004065892,-0.025227002999999998,0.087424794,-0.023954324,0.021263126,-0.09570210900000001,-0.015635574,1.538479399,2.493472418,0.216786093,0.741620232,0.15094841,-0.296599609,-0.49626318399999997,0.9842246170000001,-1.9594363609999998,-0.462944541,-1456.501292236615 -1343,1343,H94R,0.040591989,-0.045977258,0.007388863000000001,-0.002736263,-0.03804817,-0.01629592,0.043076134,0.038107842999999995,0.020170616000000002,-0.046142014,-0.045812501,-0.039603605,0.054381331,-0.025310362000000003,0.019837837,-0.03844372,-0.037652619,1.457469271,2.677032327,0.842006409,0.83183326,0.819648232,1.222389809,-0.188577705,1.524738449,-1.738058654,0.602780536,-1461.1921818247065 -1344,1344,H94T,0.02456609,-0.029347339,-0.014421746000000001,-0.022744182999999998,-0.049445233,0.041544952999999996,0.064000112,-0.014867933,-0.021558775,-0.046355633,-0.012339043999999999,-0.069368923,0.040525431,-0.037296703,-0.008191661999999999,-0.067247696,-0.03164277,1.349209593,2.375209477,1.072623405,1.745396797,0.9445404890000001,0.627955826,0.025415955,2.019807961,-1.229417635,1.200727691,-1456.2320592445321 -1345,1345,H94W,0.066036861,0.00686067,0.020244798,0.0065371809999999995,-0.00306571,-0.041853529,0.053395032,0.07867868900000001,0.040661334,-0.020087594,0.033808934,-0.049201088,0.089690684,-0.046324162,0.059398522999999995,-0.05942961,0.053298190999999995,1.491416527,2.5203701780000003,-4.509281258,-4.436768501,-5.147528625,-4.8701551510000005,-4.262458908,-3.829495102,-5.381376577,-4.1917987519999995,-1456.9001263054088 -1346,1346,H94V,-0.000159244,-0.058362327,-0.009146795,-0.021079719,-0.046366569,-0.012798674,0.005811352,-0.006129839000000001,-0.026702927999999997,-0.082234321,-0.034490333,-0.09333931,0.07504572,-0.042387057,0.00022762,-0.113231241,0.020498103,1.494608538,2.298426105,-0.489853593,0.120786804,-0.347753159,-1.272592705,-1.344590912,0.394882004,-2.670859345,0.110766067,-1444.012408260256 -1347,1347,H94Y,0.067546288,-0.038803866,0.000900588,-0.000901168,-0.046653887000000005,0.014666668999999998,0.084896931,0.050195644000000005,0.10696536599999999,-0.055723642999999996,-0.021884089,-0.041176998,0.042978173,-0.028474837000000003,0.026672501,-0.080862163,-0.01244561,1.1815966359999999,2.202629343,-2.45,-2.492919884,-3.442111877,-2.680290672,-1.3748181000000002,-2.259859467,-3.7761251989999995,-1.5416829380000001,-1455.9570665126666 -1348,1348,Y95A,-0.08770083599999999,-0.056902574000000004,-0.010219716,-1.6140289140000001,-2.335377871,0.002360637,-0.072638544,-0.102763127,-0.050580047,-0.015841525,-0.09796362199999999,-0.015841525,-0.004597906,-1.226193492,-2.001864336,-2.212873844,-2.457881897,0.7505663459999999,0.733658349,-12.08303249,-11.61021188,-11.68103632,-12.13920632,-13.6549644,-11.32974354,-6.711502198,-3.3058962,-1455.6750040892512 -1349,1349,Y95C,-0.07032269,-0.037206404,-0.360385767,-1.423772185,-1.6466430459999999,0.023619643,-0.050988347999999996,-0.089657031,-0.070934073,-0.02725733,-0.047155478,-0.24289109,-0.477880443,-1.5777914169999998,-1.269752952,-2.5064798219999997,-0.7868062690000001,1.339068178,0.774209275,-11.02826976,-11.38453505,-11.03307596,-10.56766299,-12.54632819,-9.609746605,-7.669257562,-4.246166911,-1456.6610454912297 -1350,1350,Y95E,-0.100184817,-0.298628637,-1.6119275180000001,-2.420311099,-2.4014968580000002,-0.065607745,-0.077015184,-0.123354449,-0.047349562000000005,-0.037981195,-0.559276079,-1.758140499,-1.465714536,-1.971215324,-2.8694068739999996,-2.355835685,-2.447158031,0.645593292,-0.022441454,-12.76149944,-13.17594809,-12.41757231,-12.35140285,-14.44701604,-11.4155579,-8.390911727999999,-5.677633867000001,-1462.625392049551 -1351,1351,Y95D,-0.08025339,-0.5247549970000001,-2.239953082,-2.3209142330000003,-2.540660619,-0.14063647599999998,-0.050835270999999994,-0.109671508,-0.031612256,-0.404849884,-0.644660109,-1.804955955,-2.6749502080000003,-1.841939521,-2.7998889439999997,-2.101621145,-2.979700093,4.229718639,2.462807461,-12.51202077,-12.84462182,-11.97595287,-11.9550758,-14.22686337,-11.55758999,-8.27892695,-6.073940624,-1463.610525848344 -1352,1352,Y95G,0.035023855,0.010731825,-0.043230041,-1.285856915,-2.275559344,-0.042499969000000005,0.054304690999999995,0.015743018,-0.068450148,-0.010964017,0.032427667,-0.067196065,-0.019264016999999998,-1.5107198119999998,-1.060994018,-2.117188922,-2.433929766,0.644768291,0.702607311,-13.88728156,-14.04757825,-13.78844032,-13.712131,-15.48557522,-12.40268303,-9.077273115,-6.735138178,-1461.3950536926277 -1353,1353,Y95F,0.005928239,-0.007574703,-0.016208142,0.015282266000000001,0.001701839,-0.016869733999999997,-0.029046564,0.040903042,-0.024569602000000003,-0.010336963000000001,-0.004812443,-0.022995328,-0.009420956,-0.010553191000000002,0.041117722,-0.012374649,0.015778326000000002,1.089169871,2.4203885019999998,-2.403114738,-2.027114235,-2.409318344,-3.4846364060000004,-2.069448074,-2.025056633,-2.693370883,-1.169213456,-1461.5054428931326 -1354,1354,Y95I,-0.057234797999999996,-0.033562878,-0.011516266,-0.031686492999999996,-0.08484952,-0.027164544,-0.113849009,-0.0006205869999999999,-0.076801332,-0.070236964,0.003111208,-0.087749879,0.06471734700000001,-0.028363264,-0.035009721,-0.177103583,0.007404544,1.506929334,2.209819059,-5.495317018,-5.690044769,-5.1216605,-5.751103546,-7.679687927000001,-3.2340883480000002,-3.2051527710000003,-0.129919317,-1446.051659005694 -1355,1355,Y95H,-0.09176343699999999,-0.002226713,-0.015098083,-0.692949887,-1.783828991,0.018856915,-0.09293572900000001,-0.090591145,-0.037039529,0.045763607000000005,-0.050217033,0.00483025,-0.035026416,-0.337533543,-1.04836623,-1.7492121369999998,-1.818445845,1.463858041,1.391535989,-9.28082283,-10.07584953,-9.245530457000001,-8.874613678,-10.03448234,-8.173638145,-8.422618133,-6.73301239,-1458.1998747540638 -1356,1356,Y95K,-0.192380133,-0.233460229,-1.429617359,-2.178474562,-2.6992509439999997,0.024596145,-0.13998867199999998,-0.244771593,0.029889615,-0.062946426,-0.40397403200000004,-1.27246144,-1.5867732769999998,-2.309445007,-2.047504116,-2.393035372,-3.005466515,0.9061017640000001,0.103353275,-13.31574802,-13.79023117,-13.41114806,-12.97895482,-15.35274277,-11.04566329,-9.840817797,-9.092961316,-1462.1271812957712 -1357,1357,Y95M,0.000388289,0.030030351,0.03807319,0.027107456000000002,-1.705062055,-0.08241757200000001,-0.002509281,0.0032858590000000003,-0.008644679,0.022011048999999998,0.038049652,0.019063813,0.057082567,-0.031653529,0.08586844099999999,-1.432261995,-1.9778621140000001,0.6683473010000001,1.322520938,-10.08700448,-10.32920718,-10.53441329,-10.36062302,-11.61988777,-7.590891136000001,-6.439095646,-1.998974396,-1447.1007053628564 -1358,1358,Y95L,-0.09639272800000001,-0.026333412999999996,-0.029250362000000002,-0.028171676,-0.912806239,-0.011345718999999999,-0.140664863,-0.052120593,-0.11341301,-0.00274069,-0.049926135,-0.027073267999999998,-0.031427455,-0.038334513,-0.018008839,-0.630697481,-1.194914997,1.135663083,1.551840374,-7.468680336,-7.9718515089999995,-8.193439468,-7.425380211,-8.127531685,-5.625198807,-4.455425847,-0.259887795,-1439.5159962233156 -1359,1359,Y95N,-0.13292859199999998,-0.11501768,-1.163358974,-2.2025470990000002,-2.6352778519999998,-0.165013877,-0.078323583,-0.18753360100000002,-0.07933708,-0.008383079,-0.221652281,-1.179510918,-1.147207029,-1.956857174,-2.448237024,-2.341477535,-2.929078169,2.359553468,0.858233032,-12.6706176,-13.18340276,-12.96967202,-11.91582143,-14.58191129,-10.702280499999999,-9.840817797,-9.092961316,-1463.7676145401783 -1360,1360,Y95Q,0.08154850599999999,0.07368965400000001,-1.090896945,-2.04595211,-2.5667284919999998,-0.07313425700000001,0.08045470099999999,0.082642311,-0.102863279,0.063636787,0.08374252,-1.208743621,-0.973050269,-1.9147339680000002,-2.177170252,-2.174415592,-2.959041392,4.019261089,2.568060487,-12.38382109,-12.90495104,-12.35305533,-11.80426182,-14.68496329,-10.17187396,-8.245324832,-5.394011011,-1459.705577811692 -1361,1361,Y95P,-0.05235467,-0.026495532999999998,-0.014449066000000002,-0.905083713,-1.99029461,-0.06386315599999999,-0.053248147,-0.051461192999999995,-0.072198277,0.005596154,-0.05858722,-0.028607452000000002,-0.00029068,-0.671360686,-1.138806739,-1.8341322969999998,-2.146456922,1.995406414,1.530036062,-13.01048665,-12.99487713,-13.05487712,-12.76651793,-14.6343652,-11.60179586,-7.847034962,-4.3884507180000005,-1455.9185765236616 -1362,1362,Y95S,-0.083270224,-0.055407662,-0.587803647,-1.5690730659999998,-2.125006547,-0.038202556,-0.072605052,-0.093935395,-0.09395777599999999,-0.018113951,-0.09270137199999999,-0.47644416,-0.6991631340000001,-1.5092044080000002,-1.6289417240000001,-2.607035212,-1.6429778819999998,1.939070296,1.010307579,-12.21303193,-12.23193242,-12.49315088,-11.19453429,-14.51744859,-10.62809349,-7.6632821689999995,-4.590043145,-1461.8903149287216 -1363,1363,Y95R,-0.045848397,-0.179156531,-1.238506919,-1.8063884069999998,-2.553313625,0.001810866,-0.009860319000000001,-0.081836474,-0.07941764700000001,-0.090343699,-0.267969362,-1.478571321,-0.9984425159999999,-2.328468244,-1.28430857,-3.0141186,-2.092508649,0.88203872,0.057384285,-11.44093877,-12.26467865,-11.90285524,-10.6346306,-13.54481596,-8.857713417000001,-7.731617653,-5.173065343,-1456.479173979722 -1364,1364,Y95T,-0.088938583,-0.014400066999999999,-0.09982331400000001,-1.55997798,-2.673178912,-0.016199543,-0.07878269,-0.099094476,-0.067801809,0.036241595,-0.065041729,-0.061332223,-0.138314405,-1.237033882,-1.8829220780000002,-2.599377848,-2.746979975,0.830698865,0.7381664490000001,-12.16538674,-11.96817904,-12.19053334,-12.460484800000001,-13.83311046,-10.37462605,-7.114778026000001,-4.2839290189999994,-1459.0447171954438 -1365,1365,Y95W,-0.021560606,0.049847117999999996,0.020868366,0.017810347,-0.029609705,-0.099855594,-0.010881095,-0.032240117,0.0263474,0.119372104,-0.019677868,0.016858213,0.024878518999999998,0.026195791,0.009424901999999999,-0.000460077,-0.058759333,1.18511676,2.704507312,-5.057599092,-5.5070110020000005,-6.810774857,-3.9720291210000003,-4.213856903,-4.784323578,-4.415219438,-2.190172783,-1454.4578237016685 -1366,1366,Y95V,-0.061207329000000005,-0.054609064000000006,-0.002049376,-0.049316092,-1.178690744,-0.014840672,-0.123815885,0.0014012270000000001,-0.031122876,-0.049768318,-0.05944981,-0.08185119,0.077752439,-0.10255952199999999,0.003927339,-0.8290039490000001,-1.528377539,1.498939425,1.6588226830000001,-6.557820639,-6.385235778999999,-6.959621147000001,-6.057320824,-8.014536346,-5.372389098999999,-5.021173484,-0.148963985,-1444.0727739389986 -1367,1367,S96A,-0.001867401,0.007803929,-0.01046151,0.011749338,-0.0036420640000000004,-0.038081264,-0.010412741,0.006677939,-0.216419998,-0.017897031,0.033504888,-0.040004224,0.019081205,-0.007493279,0.030991954,-0.01973517,0.012451041999999999,1.2088107909999999,2.514666621,-1.278011378,-1.293539932,-1.420447662,-0.722442734,-1.509714279,-1.443912285,-2.726487498,-0.7087993440000001,-1465.1903890492395 -1368,1368,S96C,-0.053363309000000005,-0.035995551,-0.048848929000000006,-0.046647174000000007,-0.716253046,0.101406944,-0.024722571000000002,-0.082004047,-0.617820539,0.008825614,-0.080816715,-0.05911371,-0.038584147,-0.044005808,-0.04928854,-0.44818847700000003,-0.984317615,1.571618666,1.942024772,-4.61375347,-5.061775848,-4.6426067810000005,-4.803973343,-4.332905289,-4.227506088,-6.280401984,-4.015016151,-1456.4885019068606 -1369,1369,S96E,-0.030868378,0.009039941999999999,-0.016716492,-0.027475466,0.0282327,0.014722289,-0.030302087999999998,-0.031434667,-0.061518038,0.031165312999999997,-0.01308543,0.013430283000000001,-0.046863267,0.011707883,-0.066658815,0.038965889,0.01749951,1.12939296,2.644671853,-1.3965868190000001,-2.301422638,-1.530477394,-1.0740489579999999,-1.034952988,-1.04203212,-2.544063136,-0.46843668899999996,-1456.9287593984045 -1370,1370,S96D,-0.049874941,0.008320542,-0.020242917,-0.049817663,-0.00321986,0.007999055,-0.034312307,-0.065437575,-0.36254803399999996,0.043622865,-0.026981781,-0.00036753,-0.040118303,-0.026186968999999997,-0.073448357,0.010053191999999999,-0.016492912,1.210836264,2.5589565640000003,-1.4443152559999999,-2.52507412,-0.7499836040000001,-1.977412346,-1.376665375,-0.592440834,-2.8824057389999997,-0.38179571,-1451.4386480101384 -1371,1371,S96G,-0.024905311,0.015297998,-0.001027734,0.005783417,0.037468031,0.013475941000000002,-0.030233523999999998,-0.019577096999999998,-0.232214265,0.032033048,-0.001437052,-0.008812105,0.006756638000000001,0.000484195,0.011082638,0.011110306,0.063825755,1.192579612,2.685602053,-0.744863864,-0.44022361,-0.795572701,-0.319081093,-2.062609932,-0.106831985,-2.994770781,-0.42199711100000004,-1464.714625345543 -1372,1372,S96F,-0.015831486000000002,-0.04016404,-0.055435258,-0.015341146000000002,-0.106211683,0.022147146,0.003811732,-0.035474702999999996,-0.420539981,-0.015399876000000002,-0.064928203,-0.039660289,-0.071210226,-0.040048656,0.009366365,-0.061930484,-0.150492882,1.299251671,2.391722178,-5.899376051,-6.587656142999999,-5.2923928380000005,-6.281559357000001,-5.105053238,-6.230218681,-6.9696696739999995,-5.167124826,-1454.1439497880638 -1373,1373,S96I,-0.040485662,0.034115543,-0.00927947,0.018133019,-0.08201615400000001,0.044546573,-0.047815620999999996,-0.033155702999999995,-0.304556087,0.073995701,-0.005764615,0.034263639,-0.052822579,0.016702424,0.019563613,-0.041603852999999996,-0.122428455,1.134415154,2.33787599,-4.4090651030000005,-5.1203946380000005,-4.553751411,-4.597449684,-3.9280571139999996,-3.845672668,-5.648004482,-3.5926032660000002,-1453.224412982352 -1374,1374,S96H,-0.067314641,-0.034136804,-0.01790189,-0.03643649,0.011625173,0.034795605,-0.062160685,-0.072468597,-0.119509985,-0.026564253,-0.041709354,-0.002355151,-0.033448629,-0.037422704,-0.035450275,0.00981028,0.013440066,1.25873652,2.6202942680000003,-1.879159442,-2.063759216,-1.713103065,-2.373119385,-1.433165276,-1.8126502690000001,-3.3012024889999996,-1.7201429680000002,-1458.1418210775591 -1375,1375,S96K,0.011290257,-0.011418876000000001,-0.008788753,-0.016388144,-0.0023632270000000003,0.000959937,0.019289143,0.003291371,0.707489833,-0.018335268999999998,-0.004502483,0.004771081,-0.022348587000000003,-0.023109601,-0.009666685999999999,-0.019828496,0.015102042,1.255113711,2.5172336459999998,-0.511834904,-0.563582542,-0.7715997090000001,-0.752966438,-0.143220604,-0.327805229,-2.640425569,0.15467129400000001,-1463.5156522891484 -1376,1376,S96M,-0.055335216,0.018833219,0.005462531,0.002873301,-0.0196778,0.016606521000000003,-0.05502877900000001,-0.055641653,-0.36254803399999996,0.069216344,-0.031549906,0.003985027,0.006940035,0.01127491,-0.005528308000000001,0.026697778,-0.066053377,0.9547578290000001,2.4463254880000003,-3.9639921019999997,-4.495159576,-3.657747467,-4.191444359,-3.478028625,-3.997580482,-4.976318378999999,-2.380560391,-1459.055082329549 -1377,1377,S96L,-0.01543998,0.010835811,-0.00040538099999999996,0.002699527,-0.025364385,0.03622999,-0.003850314,-0.027029646,-0.119509985,0.035085115,-0.013413494,0.01691705,-0.017727811,-0.0051692990000000005,0.010568353,-0.032215055,-0.018513714,1.206292786,2.495999607,-2.386765623,-3.526179642,-1.573074501,-2.951202126,-1.5869829709999999,-2.296388878,-4.01691176,-1.4846035640000002,-1457.108753059525 -1378,1378,S96N,-0.016254759,-0.022475986,-0.001846978,0.011931873,0.009597091,-0.01613118,-0.038361558,0.00585204,-0.324759473,-0.055259631,0.01030766,-0.035565808,0.031871852,-0.0007746210000000001,0.024638366000000002,-0.021039896000000002,0.040234078,1.543610422,3.106887046,-1.49374707,-1.8134411769999998,-1.6786697080000001,-1.946646545,-0.788955574,-1.2410223470000001,-2.3937049619999997,-1.344282278,-1457.599998907186 -1379,1379,S96Q,-0.033473393,-0.023366829,0.011022466000000002,-0.02653964,0.048938315999999996,0.039399807,-0.050603779,-0.016343006,-0.36254803399999996,0.008306374,-0.055040032,0.003805158,0.018239774,-0.033430866000000004,-0.019648413,0.020709743,0.077166889,1.2800366159999998,2.710921859,-1.316956718,-1.328183952,-1.86609082,-1.170992157,-0.7678313370000001,-1.451685326,-2.632282178,-0.84245369,-1460.8558038612828 -1380,1380,S96P,-0.043877309,-0.0017465129999999999,-0.007789765,-0.021045379,-1.456086594,0.039891017,-0.022432009,-0.065322608,-0.033122666,0.014523593999999999,-0.018016618999999998,-0.0047095670000000004,-0.010869963,-0.0014131870000000002,-0.040677571,-1.397266294,-1.5149068940000001,0.8221191729999999,1.336818778,-2.221355354,-3.4958479839999996,-2.777946533,-1.109350533,-1.309988503,-2.413643219,-3.598775005,-0.7416274959999999,-1455.7093315301463 -1381,1381,S96R,-0.028353079,-0.017692668,-0.011650031000000002,-0.021686612999999997,0.0037683190000000004,0.010297094,-0.025659188,-0.03104697,-0.178903637,-0.017893066000000003,-0.01749227,-0.024280611,0.000980549,-0.02366,-0.019713225,-0.025080646,0.032617283,1.266887541,2.476383067,0.535323428,0.349915962,0.7991299359999999,0.46397360200000004,0.396005867,0.667591774,-0.7323179479999999,0.28071299899999996,-1460.121834156569 -1382,1382,S96T,5.8599999999999995e-05,0.007634001,0.010590375,-0.020313983,0.032250079,0.014165811,0.004663629,-0.004546483,0.211483234,-0.006167469,0.021435471,-0.011753862,0.032934611,-0.016943571,-0.023684395,-0.009761289,0.07426144700000001,1.1992141440000001,2.564123395,0.250449315,0.523665321,0.131489204,0.126006721,0.299737839,0.17134748800000002,-1.233915839,0.852803525,-1464.8063841694966 -1383,1383,S96W,-0.051347789000000005,-0.030122277000000003,-0.022056507000000003,-0.027889759,-0.34578657,0.04836397,-0.002456749,-0.100238828,0.415603217,-0.0014744629999999999,-0.058770090999999997,-0.014290711999999999,-0.029822302000000002,-0.019028701000000002,-0.036750816,-0.279428354,-0.412144785,1.320101189,1.928781018,-6.284584436,-6.922490532,-5.555696739,-6.617023445,-5.700796767999999,-6.626914696,-7.845625234,-6.935128809,-1455.3118311483413 -1384,1384,S96V,-0.05593132,-0.008019128,-0.047026306,-0.01739867,-0.031687321000000004,0.037263485,-0.040657393,-0.071205247,-0.36254803399999996,0.034222563,-0.050260818,-0.024063469,-0.069989142,0.013745425,-0.048542764,-0.010383308,-0.052991333,1.318602805,2.642984867,-3.012049365,-3.5857973710000004,-3.447556633,-2.6094522319999998,-2.649790749,-2.7676498410000003,-4.291263542,-2.008247049,-1456.1890658517368 -1385,1385,S96Y,-0.083757906,-0.045405409,-0.038051755,-0.041922627999999997,-0.090141803,0.020060623,-0.066874639,-0.10064117199999999,-0.408305524,-0.023087229,-0.067723588,-0.027158032999999998,-0.048945477,-0.019377791000000002,-0.064467464,-0.09270448,-0.087579126,1.3479422719999998,2.262875996,-4.335690787,-4.712930237,-4.23008728,-4.686171599999999,-3.6429133910000004,-4.406351425,-6.231547332000001,-3.14045519,-1448.4784169332124 -1386,1386,Q97A,-0.01178375,-0.020786042,0.002297365,0.055621348,-0.019611956,0.041292018,0.025714023,-0.049281522,0.04408119,-0.019223291,-0.022348792000000003,-0.003661046,0.008255776,0.002120941,0.109121754,0.012281097,-0.051505008,1.297655796,2.712141618,-1.412247394,-0.42550209,0.19141443600000002,-2.040151443,-3.8905439989999997,-0.896453873,-2.764545019,0.873521775,-1452.9110207469203 -1387,1387,Q97C,-0.10734501199999999,-0.017768938999999997,-0.041538151,0.003076517,-1.576997734,0.16818346,-0.058892362000000004,-0.155797662,0.074331421,-0.045696012,0.010158134000000001,-0.044553978,-0.038522324,0.010978979,-0.004825945999999999,-1.5056762769999998,-1.64831919,0.7259613840000001,1.323414735,-7.32499118,-6.31143457,-6.090348145,-8.439606857000001,-9.107682457000001,-6.675883872999999,-8.386624201,-6.441058645,-1455.7779791257344 -1388,1388,Q97E,-0.063623807,-0.022325637000000002,0.001899499,0.037051467000000005,0.002158724,0.081328079,-0.025164256,-0.10208335800000001,0.136780583,-0.002818989,-0.041832284,-0.016669531,0.020468529,0.009069001,0.065033932,0.022480002000000002,-0.018162555,1.269608364,2.781116593,-0.537129779,-0.058132301,0.7104683690000001,-1.2395806809999999,-1.390954323,-0.7074499590000001,-2.061800863,0.65790647,-1451.6052744123153 -1389,1389,Q97D,-0.018227653,0.044454985999999995,0.006432205999999999,0.048878659000000005,-0.002857923,0.11320185099999999,0.028509721000000002,-0.064965026,-0.001165372,0.10979243699999999,-0.020882465,0.060584266,-0.047719855,0.036189708,0.06156761,0.058075862,-0.063791707,1.198917167,2.858142857,-3.0336619519999997,-1.910598663,-1.835028305,-4.140161957,-5.095159035,-2.1873618009999998,-3.950145627,-0.029194151,-1446.497289382387 -1390,1390,Q97G,-0.046372329000000004,-0.0036467440000000004,0.012263541000000001,0.052632020999999994,-0.01401232,0.055798469,-0.025045401000000002,-0.067699257,0.017072969,-0.001533267,-0.00576022,0.0060084,0.018518681000000002,0.011893975,0.093370066,0.008296743,-0.036321383,1.543610422,3.106887046,-3.8247182860000004,-2.639819641,-2.371761444,-5.298431686,-5.702301788,-3.1112768710000003,-4.280951049,-1.53256485,-1449.7249545105733 -1391,1391,Q97F,-0.027954389,0.007563676,0.018163898,0.07681640599999999,-0.075288388,0.027087037,-0.046255789000000005,-0.009652989,0.09241302900000001,0.017488493,-0.002361141,-0.000337312,0.036665107,0.046196368,0.107436444,0.01378671,-0.164363486,1.159932201,2.655793289,-6.332944406,-4.938813789,-5.4011706770000005,-7.958062126000001,-8.132553459,-5.234121979,-6.905060988,-4.037158822,-1458.9579704767093 -1392,1392,Q97I,-0.082261301,-0.061406409,-0.118546134,0.000176779,-0.050842347999999996,0.08128898400000001,-0.00696037,-0.157562231,0.031813779,-0.053877924,-0.068934893,-0.09225482900000001,-0.144837439,-0.029400806,0.029754363,-0.030129816,-0.071554879,1.134089548,2.3888916890000003,-5.02927417,-3.833514175,-4.562556273999999,-6.3738156660000005,-5.956702614,-4.41978212,-6.082620241,-2.564586313,-1453.2255967990495 -1393,1393,Q97H,-0.038335157,-0.005533636,-0.023930157,0.020981771,-0.091936105,0.08796825900000001,-0.008770824,-0.06789949,-0.0011158589999999999,0.004114023,-0.015181294,-0.040040721,-0.007819592,-0.025390671,0.067354213,0.020480178,-0.204352388,1.1634596990000001,2.579968909,-3.7136412930000002,-2.9960353160000004,-3.026735413,-4.551973236,-4.972199165,-3.021263336,-5.43519128,-2.250006116,-1456.585748030804 -1394,1394,Q97K,-0.126185616,-0.0007452180000000001,0.045289667,-0.031884997000000005,-0.010289612,0.037450519,-0.129459959,-0.12291127199999999,0.09017402,0.073318568,-0.074809004,0.040341418999999996,0.050237914,-0.012997924,-0.05077207,0.052986732,-0.073565955,1.098010228,2.749975142,0.155567873,0.591089355,0.723372887,-0.393737213,-0.332330948,0.189445282,-1.84543887,1.056956588,-1462.5937148192897 -1395,1395,Q97M,-0.067446126,-0.048332581,-0.01690647,-0.017686759,-0.077931497,0.040252618999999996,-0.045920329,-0.088971922,0.045675655,-0.030906345,-0.065758817,0.029652955,-0.06346589400000001,-0.005445546999999999,-0.02992797,-0.05828730000000001,-0.097575694,1.5464736069999998,2.938183126,-4.969837845,-4.187673988,-4.469774353,-6.31179303,-6.103762741000001,-3.776185112,-5.9483184289999995,-3.0364833989999997,-1456.1841251114383 -1396,1396,Q97L,-0.028161022,-0.010277035,-0.030235466000000003,0.021141949,-0.010569208,0.021105557999999996,0.002858185,-0.059180228,0.08937674599999999,-0.0009201810000000001,-0.019633888999999998,-0.020907735,-0.039563196,-0.004544355999999999,0.04682825400000001,0.005393947,-0.026532363,1.1306588690000001,2.487209058,-4.031868669,-3.2007987289999997,-3.9090277789999996,-5.4769343720000006,-4.600824966,-2.9717575000000003,-5.63322917,-2.235617769,-1451.160909023136 -1397,1397,Q97N,-0.08405011300000001,-0.043539549000000004,-0.014466392,0.03604303,-0.09614658300000001,0.119263964,-0.0021027529999999997,-0.165997473,-0.020475915,-0.110978286,0.023899188,-0.01106775,-0.017865033,0.006619039,0.06546702,-0.051836342,-0.140456824,1.273551708,2.438066222,-3.4996937530000003,-2.47664122,-2.8199089510000004,-4.740303268,-4.479600693,-2.982014633,-4.63087206,-0.354847928,-1457.259225600399 -1398,1398,Q97P,-0.05300426,-0.048890939,0.0028949270000000003,0.020299373,-0.033617087000000004,0.035344524,-0.041817999,-0.064190521,0.068123327,-0.005985857,-0.09179602099999999,-0.020155523999999998,0.025945377000000002,-0.029888355,0.07048710000000001,-0.000324686,-0.066909487,1.1391985340000002,2.4211962280000003,-1.8958555240000001,-0.49771650700000003,-0.6557459489999999,-3.69503241,-3.2205861739999997,-1.410196579,-2.74975932,0.842874219,-1444.6064956141636 -1399,1399,Q97S,-0.038334711,-0.025954396,-0.010194942,0.057304561,-0.015191231999999999,0.045280699,0.005589508000000001,-0.08225892900000001,0.05229580599999999,-0.020424008,-0.031484784,-0.007081889,-0.013307995,0.023433189,0.09117593199999999,0.018671557,-0.04905402,1.101222184,2.6210884290000003,-2.0268087340000003,-1.14127919,-0.307115646,-3.0163728489999997,-3.629163399,-2.040112587,-3.5287744830000003,-0.265720842,-1453.281307314057 -1400,1400,Q97R,-0.05173822,-0.027682987000000003,-0.0057095240000000005,0.044221478,-0.025489968,0.047576151,-0.027706875,-0.075769564,0.115186463,0.010267206999999999,-0.065633181,0.007776341,-0.019195388,0.018878261,0.06956469400000001,0.022290196,-0.073270132,1.123902709,2.683513769,-0.8327057109999999,-0.634364746,-0.096529015,-1.025385788,-1.9213386609999998,-0.485910347,-2.1047231490000002,0.714424365,-1458.0978910005651 -1401,1401,Q97T,-0.033832614,-0.026347409,-0.017490861,0.037239475,-0.032345228,0.066863271,0.003338502,-0.07100373,0.08892658699999999,-0.024937774,-0.027757043,-0.031973099,-0.0030086229999999998,-0.021786547000000003,0.09626549599999999,-0.020955939,-0.043734517,1.239348798,2.5122110980000003,-3.016581023,-1.8698046259999999,-1.635979866,-4.145479553,-4.679944023,-2.7516970439999997,-3.904692295,-1.365166625,-1454.5626050145365 -1402,1402,Q97W,-0.062078337000000004,-0.049287777000000005,-0.013915967,0.007019788000000001,-0.079322043,0.048114653,-0.031138587000000002,-0.093018087,0.09688724,-0.029755155,-0.068820398,0.032161028,-0.059992962000000004,-0.025794532000000002,0.039834107,-0.043496531,-0.115147555,1.3863315019999998,2.59155476,-5.386335599,-4.313519882,-4.591717194,-6.7542219470000004,-7.144302109,-4.127916862,-6.007852069,-3.090499608,-1456.3638994074427 -1403,1403,Q97V,-0.015442053999999998,0.012150015,0.008421494,0.045222625,0.021819069,0.057853798,0.01693819,-0.047822298,0.088777875,-0.0031780590000000004,0.027478087999999998,0.011111801999999999,0.005731185,0.017556313,0.072888936,0.027388016,0.016250121,1.211539417,2.7639567260000004,-3.9000154210000004,-3.017297806,-2.9981322169999998,-5.06134536,-5.525716782000001,-2.897584938,-4.732161436,-1.751594875,-1453.963032352738 -1404,1404,Q97Y,-0.09024597300000001,-0.014839268999999999,-0.045435635,0.031308355,-0.08975712300000001,0.04509579,-0.023865361,-0.156626585,-0.025854386,-0.009496026,-0.020182512,-0.004682466,-0.08618880400000001,0.00020774700000000002,0.062408963,-0.041899597000000004,-0.137614649,1.247006319,2.456622331,-6.1545489689999995,-4.610100815,-5.350209641,-7.86407605,-8.227004013,-4.721354324,-6.769203571,-4.037158725,-1458.9251985079609 -1405,1405,N98A,0.004424573,-0.014009134,-0.021701758999999998,-0.036849619,-0.054690586,-0.01574315,-0.011678973999999998,0.020528118999999997,-0.221688318,0.007309899999999999,-0.035328168,-0.033964612000000005,-0.009438905,-0.042588905,-0.031110332,0.010200534,-0.119581706,1.16137238,2.560048067,0.781464713,1.2018165440000002,-0.21422881300000002,0.969553642,0.3014104,1.64877179,-1.912630785,1.984376224,-1456.656405998394 -1406,1406,N98C,0.081171246,-0.02226127,-0.071471747,-0.143726178,-1.668090614,-0.099336077,-0.047720689000000004,0.21006318100000002,-0.059352293,-0.0016997529999999998,-0.042822787,-0.057322146,-0.08562134699999999,-0.066666433,-0.220785923,-1.563563726,-1.772617501,0.909002869,1.333090846,-4.195735045,-3.960493927,-5.020238495,-4.392549988,-4.093222969,-3.5121698460000004,-5.575185635,-2.7465093489999997,-1458.10237964103 -1407,1407,N98E,-0.060883854,-0.066025394,-0.045896015,-0.07035511400000001,-0.09112556699999999,-0.009761176,-0.098571992,-0.023195716,-0.09456552,0.003316587,-0.135367374,-0.037451164,-0.054340865,-0.070516471,-0.070193756,-0.009680459,-0.172570675,1.418178283,2.641941297,0.540609685,0.9309057079999999,0.32034845,-0.049115028,0.334837814,1.16607148,-2.394245176,1.881546436,-1451.1698772814125 -1408,1408,N98D,0.021104186,-0.0022073320000000002,-0.003625583,-0.031768604,-0.031768977000000004,-0.020744895,-0.000919298,0.043127669,-0.16866724100000002,0.043963792,-0.048378455,0.010519899,-0.017771065,-0.05407826599999999,-0.009458942,0.037580881000000003,-0.101118834,1.2552481000000002,2.736244553,0.9197443390000001,0.8927578890000001,0.959958069,1.119556129,0.8409990009999999,0.785450607,-2.037772905,1.617415587,-1454.7062157550827 -1409,1409,N98G,-0.004499332,-0.041130433,-0.031414219,-0.058506797,-0.061982212,-0.012741225,-0.029592253,0.020593589,-0.089485995,-0.029756774,-0.052504090999999996,-0.019080354,-0.043748083,-0.081964854,-0.03504874,-0.025529451,-0.098434972,1.401647666,2.585036644,-0.174039737,0.29059293399999997,-0.320846657,0.13343605,-0.88938092,-0.084000092,-2.971876762,0.906377946,-1460.6433859756216 -1410,1410,N98F,0.001768825,-0.0076999780000000006,-0.00020354099999999998,-0.034917647,-0.022139397,-0.042785635,-0.029281225,0.032818875,-0.142923736,0.005540664,-0.02094062,-0.012149763999999999,0.011742681999999999,-0.058555285,-0.011280008999999999,0.015250317,-0.05952911,1.104579495,2.627155609,-4.654500285,-3.99240062,-5.819995842000001,-4.616950424,-5.2310901869999995,-3.6120643539999997,-5.006562509,-2.311884708,-1458.679554165341 -1411,1411,N98I,0.011351267,-0.028654446,-0.017715678000000002,-0.046885397999999995,-0.047687942000000004,0.009490216999999999,0.004414662,0.018287872,-0.0255355,-0.021791517000000003,-0.035517374,-0.056541234,0.021109878999999998,-0.083925794,-0.009845002,0.006112328,-0.101488212,1.101056876,2.457562682,-3.9751101230000003,-3.8369747010000004,-5.006561501,-3.358556221,-4.497249985,-3.176208206,-4.505271115,-1.652045349,-1457.0870086159557 -1412,1412,N98H,0.015152871000000002,-0.02890307,0.006697071,0.005904942,-0.049312425,-0.015938832,0.0010662269999999999,0.029239515,-0.16549719400000001,-0.014048253,-0.043757887,0.0021075670000000003,0.011286573999999999,-0.027808156,0.03961804,0.036741481,-0.13536633,1.1453971440000001,2.602042605,-0.965591313,-1.391428795,-2.121643555,0.161796745,-0.571994667,-0.904686295,-2.8280618110000004,-0.661646317,-1455.2725241212174 -1413,1413,N98K,0.042041521,0.0007411439999999999,0.021190492000000002,-0.011860271,-0.033608341,-0.037479537,0.030731922000000002,0.053351119,0.079510447,0.003729933,-0.002247646,-0.005520766999999999,0.047901751,-0.027342407000000003,0.003621865,0.01930834,-0.086525022,1.2585913659999999,2.7027239410000004,0.202931544,0.841597626,-0.548608467,-0.198922386,-0.057519600000000004,0.97811055,-2.9278299760000004,1.025147372,-1454.05535292672 -1414,1414,N98M,-0.054674979000000005,-0.056781705999999994,-0.056999271,-0.09000504,-0.09343678300000001,-0.018537924,-0.079602267,-0.02974769,-0.14384365699999999,-0.042738438,-0.070824973,-0.056557352000000005,-0.05744119,-0.10173535199999999,-0.078274728,-0.014399035,-0.17247453,1.2739935759999998,2.399096019,-4.637998022,-4.119321793,-5.663316032000001,-4.723223419,-5.223176445,-3.460952423,-5.6068736789999996,-3.1489867960000004,-1454.4831163287163 -1415,1415,N98L,-0.023855183999999998,-0.008639403,-0.015058771,-0.039489012000000004,-0.050658885,-0.041127783,-0.03009783,-0.017612538,-0.166472721,0.02757634,-0.044855146,0.017809244,-0.047926785,-0.035112381,-0.043865642,0.032481803999999996,-0.133799573,1.274576722,2.778318422,-4.20884799,-4.204166809,-5.330834785,-3.7892817919999997,-4.348469147,-3.3714874189999997,-5.568494152,-2.118202807,-1456.108894905541 -1416,1416,N98Q,-0.010719589,-0.027341094,-0.038164171000000004,-0.06074866599999999,-0.053535029000000005,0.06641855599999999,-0.013954268999999998,-0.0074849090000000005,-0.217885264,-0.016053618999999998,-0.038628569,-0.019971824,-0.056356517,-0.061540722,-0.059956609,0.008382872,-0.11545292900000001,1.1837811109999998,2.542245079,0.330404889,0.297806,0.051135941,1.1664465640000001,-0.231368706,0.368004646,-1.565293439,0.22332183,-1452.5026297718287 -1417,1417,N98P,-0.020158334,-0.008225111,-0.022395536,-0.033124086000000004,-0.082870102,0.009425456,-0.043321128,0.003004461,-0.21151461800000002,0.009947145,-0.026397366000000002,-0.015658365,-0.029132707,-0.046745179000000005,-0.019502993,-0.030364662,-0.135375541,1.198251735,2.327531613,-4.111570451,-3.862544655,-5.172904396,-3.8833809969999997,-4.3925396580000005,-3.246482552,-4.651656141,-0.670724134,-1459.3216289202683 -1418,1418,N98S,-0.03598568,-0.009592535,-0.022248828,-0.035697131,-0.049634646,-0.025664537,-0.06433409799999999,-0.007637260999999999,-0.207357271,0.035978512000000004,-0.055163582,0.004371674,-0.04886933,-0.048063392,-0.02333087,0.013192259,-0.11246155099999999,1.187801133,2.5553452269999997,1.04628614,1.426737839,0.982935432,0.317331047,1.362898384,1.141528,-1.250379407,1.900475956,-1456.892403899692 -1419,1419,N98R,0.0061322880000000005,-0.017207493,-0.015119108999999999,-0.029459791000000003,-0.043622887,-0.000939688,-0.012678571000000001,0.024943147000000002,-0.17411146,0.010778688,-0.045193674,-0.010840276000000001,-0.019397941999999998,-0.025212382000000002,-0.03370719999999999,0.023742546,-0.110988319,1.671448915,3.643209181,-0.069411771,0.1007183,-1.505371368,0.796562515,0.154301468,0.106730232,-2.9914607280000003,0.361342275,-1449.1162100732327 -1420,1420,N98T,-0.03565817,-0.018741746,-0.037001757,-0.02993934,-0.056332568,-0.025935202999999997,-0.064812016,-0.006504323,-0.143113137,-0.005281109,-0.032202383,-0.010884443,-0.06311907,-0.031530725,-0.028347955,0.008916281,-0.121581417,1.149938831,2.549274354,-0.554833173,-0.26993206,-0.944186981,-0.874656433,-0.193412384,-0.49197800399999997,-3.0152901589999996,0.436962965,-1457.1066899276339 -1421,1421,N98W,0.012140661,-0.019065927,-0.014553523,-0.057602724,-0.040330557999999996,-0.015758444,-0.02665635,0.050937672,-0.202930445,0.013150384,-0.051282238,0.004926683,-0.034033729,-0.035019837000000005,-0.08018561099999999,0.024306665,-0.10496778,1.107887337,2.59724708,-6.085929366,-5.9115820470000005,-6.731229904,-5.736607941,-6.599089142,-5.451137794,-7.91037194,-6.695511649,-1455.7557900133543 -1422,1422,N98V,-0.041429824,-0.021845772000000003,-0.022500507000000003,-0.044302182999999995,-0.048610582,0.019313926999999998,-0.057592067000000004,-0.025267581,-0.119427311,0.022829976000000002,-0.066521519,-0.00022031,-0.044780704000000005,-0.047845519,-0.040758846,0.046457312,-0.143678476,1.172144321,2.639365773,-3.3079825869999997,-2.863842064,-4.365923308999999,-2.7014003910000004,-4.267217934,-2.341529236,-4.183675522,-1.098257545,-1457.1542230220512 -1423,1423,N98Y,-0.05282454599999999,-0.040095601,-0.024513781000000002,-0.035463022000000004,-0.019943187,-0.161192221,-0.090916303,-0.014732788,-0.177696558,0.039404399,-0.119595601,0.0015032889999999999,-0.050530850999999995,0.005792898,-0.076718942,0.038047919,-0.077934292,1.097788313,2.717351358,-3.841918619,-3.6693262410000003,-5.249736496000001,-3.7440200580000003,-3.761120567,-2.785389732,-5.093320008,-1.479884786,-1455.525369568728 -1424,1424,D99A,0.05969738,-0.037313322,0.028030612000000003,-0.025900744,-0.161376064,-0.017801836,0.051124080999999995,0.068270679,-0.013005686,-0.048973609,-0.025653035,-0.010398523,0.066459747,-0.033222944,-0.018578544,-0.163451945,-0.15930018199999998,1.432700019,2.197139854,-4.23175918,-3.991547493,-5.450327667000001,-4.035530869,-2.46140387,-5.2199860000000005,-3.448876903,-2.8327201730000002,-1455.7524134349078 -1425,1425,D99C,0.257449568,-0.000131394,0.047169645999999996,-0.576618337,-1.991657821,-0.078596162,0.077662647,0.437236489,-0.062960263,-0.055349153,0.055086366,-0.016990718000000002,0.11133000900000001,-0.306662657,-0.846574017,-1.8187992130000001,-2.164516429,1.466399851,1.3799508280000001,-9.41817417,-9.313141242999999,-11.42490857,-9.525401085,-7.391768341000001,-9.435651611,-7.893012146,-6.183850052,-1460.1368747781962 -1426,1426,D99E,0.041193925,0.008852435,-0.006571978000000001,-0.018170338,-0.05227557099999999,0.030824424,0.046337925999999995,0.036049924,0.035493464,-0.04289147,0.060596339000000006,-0.053250486,0.04010653,-0.02691298,-0.009427696,-0.076077906,-0.028473235,1.314858748,2.331832241,-2.7088392239999997,-2.1953058619999997,-4.066515076,-2.671161079,-1.712688293,-2.89852581,-3.222577307,-1.812277586,-1456.1789903878234 -1427,1427,D99G,0.01001503,-0.035958625,0.005166134,-0.03399626,-1.6564993719999999,0.002235904,0.00811231,0.011917748999999998,0.017117147,-0.089126563,0.017209313,-0.044526576,0.054858843,-0.022279685,-0.045712834,-1.620385305,-1.692613439,0.8420426540000001,1.323853187,-6.785933836,-6.803525802999999,-8.108190697000001,-6.213188087000001,-5.1906619339999995,-7.614102661,-5.6389083939999995,-3.759315928,-1453.682130415924 -1428,1428,D99F,-0.063742016,-0.05460808,0.023652182999999997,-0.062770108,-1.484216288,-0.001012625,-0.09551145,-0.031972582,-0.012489735,-0.112916511,0.003700352,-0.016287677,0.063592042,0.006021483,-0.131561699,-1.248010144,-1.720422432,0.7002605,1.336323267,-9.539319472999999,-9.643980988,-11.40240302,-9.35550396,-8.30620443,-8.988504974,-6.275229242000001,-3.825376879,-1462.907820172608 -1429,1429,D99I,0.003891849,-0.06921793400000001,0.010444287,-0.01354972,-0.877720052,-0.0009801410000000001,-0.011553548,0.019337246000000002,0.011402603,-0.113615015,-0.024820852999999997,-0.073055549,0.093944123,-0.064649238,0.037549799,-0.625868277,-1.1295718270000001,1.1850305209999998,1.576904831,-8.602468781,-9.823257355,-9.644177597,-8.661802681000001,-6.732118645,-8.150987625,-6.409475691,-4.349427034,-1456.2057328247465 -1430,1430,D99H,0.039733338,0.014870525,0.02323663,-0.023458897000000003,-0.172785852,-0.023017147999999998,0.038609508,0.040857167,0.10315563400000001,-0.01424002,0.043981069000000005,0.024666485,0.021806773999999998,0.035249584,-0.082167378,-0.145605622,-0.199966082,1.443704994,2.3238305880000003,-6.360419237,-7.263210526,-7.8996945720000005,-5.833371689,-5.188454002,-5.617365395,-6.446489923,-3.244715812,-1460.0954532851465 -1431,1431,D99K,-0.011158986999999999,-0.036058634,0.004606321,-0.086114675,-0.7008136629999999,0.019587476,-0.006958789,-0.015359185,-0.041138733,-0.094567408,0.02245014,-0.056562865,0.065775507,-0.018610797,-0.153618552,-0.475721626,-0.9259056990000001,1.5298437740000002,1.87293527,-5.356528409,-5.915688927000001,-7.659986694,-3.5010073389999996,-4.994934509,-4.711024574,-5.216543729,-3.91408782,-1454.6594596751966 -1432,1432,D99M,0.014362814,0.008897899,0.006360406,-0.052730501,-0.144838937,0.010476713,0.013809325,0.014916302,-0.008809655,-0.01980212,0.037597917,0.04130732,-0.028586509,-0.036820072999999995,-0.068640928,-0.141419477,-0.148258396,1.4852625419999999,2.319238645,-6.073796165,-7.721005402,-6.348201744,-5.896726723,-4.321337326,-6.081709632999999,-5.580931946000001,-3.434262598,-1460.7614956223406 -1433,1433,D99L,0.06381155,0.001013681,0.019424333999999998,-0.011030367,-0.589505055,0.011371613999999999,0.046747624,0.080875476,0.046902817,-0.034518732999999996,0.036546095,0.010497693,0.028350973999999998,-0.0013759129999999999,-0.020684821000000003,-0.489155204,-0.689854906,1.048477467,1.579124131,-7.6815260379999994,-8.680904831,-9.351670448,-7.904357612999999,-5.532943596,-6.9377537,-5.940654443,-2.8447145860000003,-1459.6979569382966 -1434,1434,D99N,0.061149347,-0.024148244,-0.04954016,-0.028789322000000003,-0.257325475,-0.059113535,0.09005025400000001,0.032248439,-0.021952113,-0.091642215,0.043345727,-0.10350577300000001,0.004425453,-0.011299165,-0.046279479000000005,-0.252494705,-0.262156244,1.438567451,2.059079851,-4.547261252,-5.3857472920000005,-4.949283432,-3.660800117,-4.285036667,-4.455438751,-4.514223828,-3.030382515,-1457.7956048650667 -1435,1435,D99Q,0.10186898400000001,0.064430179,0.068215427,-0.012286406000000001,-0.07651013799999999,-0.062970579,0.064791282,0.138946685,0.024431732,-0.037210507000000004,0.166070864,0.020901576,0.11552927699999999,-0.027663224,0.0030904129999999998,-0.168713363,0.015693088,1.5575439359999999,2.327750822,-3.672040074,-3.91761692,-5.356920395,-3.4300271380000003,-2.533621414,-3.122014503,-3.5693769989999997,-2.8851756689999997,-1458.1738786408678 -1436,1436,D99P,0.017780245,-0.000674694,0.031433897,-0.6336250520000001,-2.0321325630000002,-0.036428736,0.016774155,0.018786334,0.046075572999999995,-0.031597331,0.030247944,-0.005945605,0.068813398,-0.365062465,-0.9021876390000001,-1.935153436,-2.12911169,1.4517153230000002,1.351869571,-7.607034999,-7.87255098,-8.353636406,-7.909751076,-5.607567665,-8.291668869,-5.796579245,-4.703422496,-1453.6897452715784 -1437,1437,D99S,0.059156312999999995,-0.023519996,0.021995325,-0.021117292000000003,-0.17350284800000002,-0.003275804,0.07863732799999999,0.039675298,0.02274548,-0.052976454000000006,0.005936461999999999,0.01438311,0.02960754,-0.016245831000000002,-0.025988753,-0.20466970199999998,-0.142335993,1.470013363,2.1658987880000002,-5.242174524,-5.591190117000001,-5.9060521470000005,-4.729450645,-4.042972618,-5.941207092000001,-4.939122278,-2.58330614,-1455.1302360463887 -1438,1438,D99R,0.043124347,-0.009609758000000001,0.02024732,-0.03447462,-1.245599476,-0.005196682,0.057492750999999995,0.028755943,-0.009789434,-0.035857995,0.016638478999999998,-0.012359901999999999,0.052854542000000004,-0.02679829,-0.04215095,-0.9817136890000001,-1.5094852630000002,0.7377620570000001,1.362212404,-6.1358917470000005,-6.72232869,-8.116874603,-5.306523651,-5.002279045,-5.531452744,-6.438932212,-3.05567356,-1455.212691591587 -1439,1439,D99T,0.045820717000000004,-0.055323664,-0.02861519,-0.045525677,-0.40917352799999995,-0.0175048,0.038851379,0.052790054,0.046331001,-0.081428322,-0.029219006000000002,-0.070046259,0.012815878999999999,-0.058927424000000006,-0.03212393,-0.40616429200000004,-0.41218276299999995,1.531851368,1.9455833809999998,-5.938374051,-6.495173615,-6.75727317,-5.660947441,-4.425627396,-6.352848633,-5.046618357,-3.815897498,-1458.0654447148554 -1440,1440,D99W,-0.114648221,-0.089662891,-0.02026665,-0.02426897,-1.876323526,-0.007905995,-0.127657118,-0.101639324,-0.027246125,-0.018138471,-0.161187311,0.056028294000000006,-0.096561594,0.048703465,-0.097241405,-1.676541614,-2.076105437,0.571382956,1.305859542,-9.552569899,-9.90162693,-11.29582437,-10.33617104,-8.245996932999999,-7.983230225,-7.82718039,-6.161939181,-1461.7375106411055 -1441,1441,D99V,-0.022621959,-0.05738663,-0.021134105,-0.084733599,-0.354782275,-0.0038462229999999997,-0.044100115,-0.001143802,0.07382820799999999,-0.080700142,-0.034073118,-0.039758952,-0.002509258,-0.07218538099999999,-0.097281816,-0.32500759100000004,-0.384556959,1.677386192,2.145671348,-6.270678417999999,-6.979615578,-7.103794594,-6.219352524,-4.772352646,-6.278276749,-4.412421203,-2.9135714060000004,-1457.073110002093 -1442,1442,D99Y,0.053183579,-0.037141997,0.029745116000000002,-0.04101803,-1.513458825,0.004249629,0.038617923,0.067749235,0.018550188999999998,-0.039151341,-0.035132653,-0.00550998,0.065000212,-0.019142858000000002,-0.062893202,-1.20753825,-1.819379399,1.150632577,1.40953176,-9.734357687000001,-10.37588291,-12.87520291,-9.240058311,-8.097327408,-8.083316895,-5.958837476,-3.63623415,-1460.7599007058889 -1443,1443,L100A,0.008624509,-0.0121834,-0.00035680099999999996,-0.670952843,-1.8748399009999999,0.023214347000000003,0.054282935,-0.037033917,0.007229405,0.034483876000000004,-0.058850676,0.001791359,-0.002504961,-0.350772929,-0.991132756,-1.884707541,-1.86497226,1.4563281190000001,1.365293004,-10.33374989,-9.4850065,-11.48482115,-11.64229968,-9.321733658,-9.734888474,-7.605768038,-2.951748358,-1447.287077177316 -1444,1444,L100C,-0.006494503,0.0037854409999999996,-0.00299144,-0.131921006,-1.5784488190000001,0.015544671999999999,0.031295164,-0.044284169000000005,-0.003974119,0.059990518,-0.052419637000000005,-0.028802962,0.022820082000000002,-0.068445598,-0.195396414,-1.6180307859999998,-1.5388668509999999,0.934034445,1.330489842,-12.82224128,-11.61815456,-14.45777967,-15.16076732,-12.28250729,-10.59199757,-8.759084584,-3.703297913,-1455.8919701185077 -1445,1445,L100E,0.069085177,0.026311212,0.063420013,-1.264837643,-2.299156545,0.020310343,0.114810433,0.02335992,0.009706429,0.052536723,8.57e-05,0.051831058,0.075008967,-1.054939917,-1.4747353680000002,-2.41709392,-2.18121917,0.66682379,0.7384636440000001,-13.46424802,-11.23469312,-15.10226397,-14.99543226,-14.53352421,-11.45532656,-7.9765839110000005,-4.681008609,-1458.2242295411415 -1446,1446,L100D,-0.0009916360000000002,-0.057543735,-0.949085307,-2.4023945319999997,-2.838073156,0.04314573,0.05091213,-0.052895400999999995,-0.044562732,-0.032957888,-0.082129582,-0.765119311,-1.133051303,-1.859991063,-2.944798001,-2.5689325519999997,-3.107213759,2.2477273380000002,1.0361176109999999,-13.62008586,-12.22181487,-15.38080258,-15.471788199999999,-12.35701683,-12.66900681,-9.256658105,-5.710736052000001,-1455.978558626026 -1447,1447,L100G,0.04452576,-0.012661908000000001,-0.056458048,-1.482686804,-2.556103373,0.010820773999999998,0.069046912,0.020004608,0.017126442,0.0059398359999999996,-0.031263652,-0.033696927,-0.07921916799999999,-1.3727541380000001,-1.592619469,-2.257786886,-2.8544198589999996,0.829764528,0.7267228029999999,-14.38790148,-13.10093684,-15.54106105,-16.82932954,-13.88644078,-12.58173921,-8.463441861,-4.4412701,-1457.8028943818063 -1448,1448,L100F,0.012780472,-0.099574358,-0.081196897,0.017743609,-0.800498928,0.077016204,0.023983859,0.001577085,-0.067379677,-0.107300274,-0.091848441,-0.130620939,-0.031772855,-0.014714405,0.050201623,-0.640290085,-0.9607077709999999,1.089826752,1.526499346,-8.781433965,-8.611037048,-8.736151833,-10.0788875,-7.166269592000001,-9.314823845,-6.5728883279999994,-2.7411285810000003,-1449.7458611475304 -1449,1449,L100I,-0.0074133440000000005,-0.025425415,-0.065945604,0.04125572,-0.058038304000000006,-0.046753502,-0.016918523,0.002091835,-0.003705924,0.02447019,-0.07532102,-0.01078439,-0.121106818,0.07618744599999999,0.006323994,-0.017825125,-0.098251483,1.2984642990000002,2.633524663,-3.796006682,-3.470388252,-3.276826218,-4.63614193,-4.205289978,-3.391387032,-3.950540725,-0.9844488779999999,-1447.1003399677575 -1450,1450,L100H,0.12096192800000001,0.001193637,0.015603395,-0.596797806,-2.30765856,-0.038398616,0.13256462300000002,0.10935923199999999,0.040551502999999996,-0.017906398,0.020293671,-0.029786164,0.060992954,-0.46216611399999996,-0.731429497,-1.748344011,-2.8669731080000003,1.770083663,1.469609763,-15.25721549,-12.58586889,-16.86267957,-19.41557101,-13.68262695,-13.73933102,-8.320346232999999,-4.428723057,-1462.9133839374408 -1451,1451,L100K,0.015045035,0.050939232,-0.032120966,-0.59514723,-2.008377529,0.058340918,0.02151788,0.00857219,-0.06716715200000001,0.085794008,0.016084456,0.052602589000000005,-0.11684452,-0.259753107,-0.930541353,-1.7645746130000002,-2.252180445,1.232671325,1.3503532630000001,-13.84331668,-11.27451962,-17.19906342,-16.03039008,-13.06815162,-11.64445865,-8.181461087,-1.5603659730000001,-1461.1235051392578 -1452,1452,L100M,0.08106224599999999,0.003399156,0.035572192999999995,0.059511075999999996,-0.046431063,-0.082988235,0.08828796800000001,0.073836523,-0.07418519900000001,0.041089242000000005,-0.03429093,0.076825435,-0.0056810490000000005,0.06555902,0.053463132000000003,0.004581709000000001,-0.09744383400000001,1.1807842659999999,2.76503108,-5.612350417999999,-4.590950951,-6.8354943079999995,-5.636746521,-5.614126923,-5.384433388,-5.93507021,-2.229269104,-1453.5069477353245 -1453,1453,L100N,-0.03520194,-0.040607702999999995,0.002554084,-1.538654494,-2.6504243769999998,-0.005670916,0.0033220359999999996,-0.073725915,-0.025327572000000003,0.032771941,-0.11398734599999999,0.03543657,-0.030328402,-1.227408551,-1.8499004369999998,-2.209351312,-3.0914974410000005,0.6059375579999999,0.7206050820000001,-13.98995523,-12.59193236,-16.51840735,-16.67777971,-12.98877168,-11.17288505,-8.905826304,-5.556639337000001,-1460.5005727065727 -1454,1454,L100Q,-0.00752974,-0.031418546,-0.004820762,-0.07634366,-2.118330946,0.068156648,0.053867820999999996,-0.068927301,-0.11135604800000001,0.054957485,-0.117794576,0.0632825,-0.072924023,-0.0077566430000000006,-0.144930676,-1.563203935,-2.6734579569999997,0.49850068299999994,1.308308003,-13.31099151,-11.64330601,-15.79271571,-15.42940668,-12.17757915,-11.51195002,-8.012480047999999,-3.460561815,-1457.7525208587758 -1455,1455,L100P,0.009922851,-0.017830736,-0.48469101700000006,-1.666375229,-2.5742951880000002,0.023910362999999997,0.034491897,-0.014646196,-0.071032917,0.004670035,-0.040331506,-0.345200935,-0.624181099,-1.459967515,-1.872782942,-2.674058983,-2.474531393,1.576946984,0.86369468,-12.56784305,-11.57957814,-13.75393157,-14.41034171,-11.84157236,-11.25379146,-7.822430705,-3.874440405,-1456.2180866706185 -1456,1456,L100S,-0.016146079,-0.043350732,-0.002183637,-0.963785208,-1.9799980240000001,0.03002095,0.005519099,-0.037811257,-0.069093055,0.06019559,-0.146897053,0.016538736999999998,-0.020906011000000002,-0.706139745,-1.221430671,-1.7645746130000002,-2.195421434,2.078888191,1.594958114,-11.97116391,-11.60446395,-13.41348696,-15.28490882,-10.10823294,-9.444726897999999,-8.289123435,-4.067252454,-1454.571475212928 -1457,1457,L100R,0.035183038,0.028796212999999998,0.019032855,-0.900364816,-2.178643147,0.053522692999999996,0.072583005,-0.002216929,0.039455132999999996,0.04414355,0.013448876,0.01306036,0.02500535,-0.5960143689999999,-1.2047152620000001,-1.9238293480000002,-2.433456945,1.805450711,1.4326109669999998,-12.88631851,-10.7898325,-14.51293217,-15.33464972,-11.97701739,-11.81716077,-7.393167383,-1.323566,-1460.479521383997 -1458,1458,L100T,0.01287456,-0.019500061000000003,-0.008604126,0.041854564,-1.8213999280000002,0.016153498999999998,0.027241134,-0.001492015,-0.058064477,0.016325445,-0.055325566,-0.021339982,0.004131731,0.024002412999999997,0.059706714,-1.74340976,-1.8993900959999999,0.653236191,1.306784194,-10.24344375,-9.864686562000001,-11.38535329,-11.49342517,-9.973880402,-8.499873314,-7.163056435,-3.654258309,-1454.794287795201 -1459,1459,L100W,0.039834702,0.193503736,0.023915758999999998,-0.19969722199999998,-1.185561117,-0.075500213,0.077120497,0.002548907,-0.143834194,0.08996994900000001,0.297037522,-0.022402717000000003,0.070234235,-0.125243398,-0.274151045,-0.885337409,-1.485784825,1.5072491559999999,1.636807226,-12.96410663,-11.10182265,-14.53266254,-15.01579838,-11.34495219,-12.82529742,-8.537392602999999,-4.372547541,-1462.8363891202025 -1460,1460,L100V,0.022807697000000002,-0.025810865,-0.031260768,-0.0016410510000000001,-0.055273939,-0.009363071,0.0052598390000000005,0.040355554,0.018198766,-0.003786767,-0.047834962,-0.032706402999999995,-0.029815132,0.022679814,-0.025961916,-0.025233372,-0.085314506,1.296077307,2.60688446,-5.027358707,-4.456010727,-4.798056648,-5.245660141,-5.714666939,-4.922399078,-4.534087918,-1.351412077,-1450.3681633276865 -1461,1461,L100Y,0.02130023,-0.044975232999999996,-0.04621499900000001,-0.158632519,-1.5215590490000002,-0.002148319,0.048840149000000006,-0.00623969,0.023011649,-0.03769053,-0.05225993599999999,-0.011717817,-0.080712181,-0.046248145,-0.271016892,-1.557535694,-1.485582404,0.746966791,1.321193804,-12.60114666,-10.51082557,-13.405447800000001,-14.79172868,-11.09430486,-13.20342639,-8.069938448,-2.732712442,-1453.6438915263861 -1462,1462,V101A,0.008206899,-0.074177884,-0.025509105,0.00012377700000000002,-0.700294787,-0.114270741,-0.01549127,0.031905067,-0.026152135,-0.047745897,-0.10060987,-0.004642138,-0.046376072000000004,0.006913988,-0.006666435,-0.523805793,-0.87678378,1.344793343,1.732996815,-3.880361235,-4.000896461,-3.7778118519999997,-4.13847258,-3.681284386,-3.803340897,-4.2499772160000004,-1.977798999,-1443.5626543657854 -1463,1463,V101C,0.00140295,-0.054240445,-0.029033315,-0.03815164,-0.5956654929999999,0.045219282,0.003997926,-0.0011920260000000001,-0.030713266,-0.009221036,-0.09925985300000001,0.02776253,-0.085829159,-0.012394608,-0.063908672,-0.432543664,-0.7587873209999999,0.9766890770000001,1.573872006,-8.208125743,-7.445195602,-8.641171906,-9.20864167,-7.824709831,-7.920909706000001,-5.676097181,-4.648518448,-1456.1103018797003 -1464,1464,V101E,0.01716608,-0.02887265,0.00331768,0.013008437,-0.7439831159999999,-0.067678153,-0.006063003000000001,0.040395163,-0.046835444000000004,-0.019456258,-0.038289041,0.058245795,-0.051610435999999996,0.05431867,-0.028301797000000004,-0.695010265,-0.792955966,0.587891272,1.375472555,-3.985370969,-3.069192596,-4.284347839,-5.517246414,-2.866098198,-4.189969795,-3.9353534160000003,-2.854220241,-1454.1018642853014 -1465,1465,V101D,-0.085234134,-0.036065667,-0.065456291,-0.015518456000000002,-0.211748794,-0.10410034900000001,-0.09526550199999999,-0.07520276599999999,0.060365817999999995,0.005628085,-0.07775941900000001,0.014042131999999999,-0.144954713,-0.02389062,-0.007146291,-0.18608726899999997,-0.23741031899999998,1.426412995,2.138902501,-4.014523843,-2.998678535,-3.525042107,-5.957768463,-2.969657921,-4.6214721910000005,-2.768067491,-3.160112619,-1455.8682019263506 -1466,1466,V101G,-0.082446243,-0.123052652,-0.103543162,-0.058004734,-1.239269328,-0.038792621,-0.069823237,-0.09506924900000001,-0.048811615999999995,-0.14211743699999999,-0.103987866,-0.051330932999999995,-0.155755391,-0.051400975,-0.064608493,-1.091866486,-1.38667217,0.97351283,1.3887435259999998,-6.41122159,-6.194864738,-7.382337112,-6.356102562,-6.884453872999999,-5.238349663,-3.921357758,-3.41415185,-1455.3309943191707 -1467,1467,V101F,-0.051049702,-0.08482070900000001,-0.068893434,-0.015050727,-1.869255391,0.009158333000000001,-0.049471927,-0.052627476,0.021181024,-0.086754618,-0.082886799,-0.045692248,-0.09209462,-0.027755664,-0.002345789,-1.627509609,-2.111001173,0.8123136990000001,1.32068704,-9.260007652,-7.865620659,-10.16602711,-9.879875145,-9.158323142999999,-9.2301922,-6.1432449270000005,-5.495342057,-1445.4899050584063 -1468,1468,V101I,-0.0036803170000000002,-0.032331708,-0.045749995,-0.016762254,-0.10114804599999999,-0.081834226,-0.020841701,0.013481067,0.009234178000000001,0.014061253000000001,-0.078724669,0.026961249,-0.11846123800000001,0.014299131000000001,-0.047823637999999995,-0.061324348,-0.140971743,1.186960563,2.419344848,-2.131982387,-1.497711227,-2.015309097,-3.255734673,-2.22829332,-1.662863617,-1.404562806,-2.256641381,-1452.5442717522383 -1469,1469,V101H,-0.142654277,-0.070281178,-0.160339964,-0.140443256,-1.336747924,-0.037576436,-0.062560803,-0.22274775100000002,-0.032849754,-0.072748166,-0.06781419,-0.088290221,-0.232389707,-0.075882964,-0.205003548,-1.068414445,-1.605081403,1.012516162,1.399890844,-7.833984833,-6.200201767,-8.863086891,-9.964238686,-5.4473797379999995,-8.695017082,-5.508236307000001,-3.5381382360000004,-1453.4770401185378 -1470,1470,V101K,-0.045799587,-0.050880935,-0.061683167000000004,-0.026262723999999998,-0.277032486,-0.08770524099999999,-0.081031083,-0.01056809,0.03527576,-0.027970472000000003,-0.073791398,0.037573103,-0.160939436,0.008216954,-0.060742400999999994,-0.22802276300000002,-0.32604220899999997,1.04235952,1.808523932,-5.812260892,-3.5936513210000003,-6.24624646,-7.171289268,-5.389449333,-6.660668076,-4.274398338999999,-3.2189137619999997,-1452.7556211492047 -1471,1471,V101M,-0.048310375,-0.014179108000000001,-0.004076687,-0.005777791,-0.242102515,0.000534606,-0.106007802,0.009387052,0.028969499,-0.013066696000000001,-0.015291518999999998,0.0645793,-0.072732674,0.044297641,-0.055853223,-0.223513767,-0.260691263,1.435380181,2.134776638,-4.416560565,-3.2825156630000003,-5.143993752,-4.74832563,-4.505488739,-4.4024790419999995,-3.2910483680000002,-3.3427210780000003,-1452.4951419411227 -1472,1472,V101L,0.007674565,-0.062413453,-0.030946065,-0.028630777000000003,-0.08078445599999999,0.15811939,-0.019943159,0.035292289,-0.01748611,-0.073043126,-0.051783779,-0.015315171,-0.046576957999999995,-0.038212658999999996,-0.019048895,-0.119567417,-0.042001495,1.4275645730000002,2.3730432269999997,-2.0949223619999997,-0.936562508,-2.969531052,-2.891577209,-1.8813328630000001,-1.7956081769999999,-2.4194213369999997,-1.12586454,-1450.7133578686044 -1473,1473,V101N,-0.059574302999999995,-0.053307408,-0.053331051,-0.033133682000000005,-0.804123866,-0.00892416,-0.025155449,-0.093993157,0.013061946999999999,-0.023901831000000002,-0.082712985,0.023916871,-0.130578972,-0.023364056,-0.042903308,-0.688761315,-0.919486417,0.8828937790000001,1.451681311,-6.851215872,-4.87930722,-7.0299604339999995,-8.799150688,-5.910724159,-7.6369368589999995,-5.325274756000001,-3.80443933,-1456.1709176483564 -1474,1474,V101Q,0.028234629,-0.074500394,-0.064478207,-0.122584557,-0.253280102,-0.05782595,-0.0035157590000000002,0.059985015999999995,-0.048126068,-0.04617759900000001,-0.10282318900000001,-0.040191057999999995,-0.088765355,-0.112234703,-0.132934411,-0.21631756,-0.290242644,1.603270779,2.222565483,-3.8043398969999997,-2.68290757,-4.656007332,-4.925435654,-2.599790192,-4.157558739,-3.383533512,-2.830214008,-1450.9301339425147 -1475,1475,V101P,-0.044586013,-0.061496819,-0.903788175,-1.891763742,-2.538546594,-0.046694285999999995,-0.040663833999999996,-0.048508192,-0.004657149,-0.051278539000000005,-0.071715098,-0.695284123,-1.1122922259999999,-1.7306690619999998,-2.052858422,-2.577126011,-2.499967177,2.231668402,1.088860772,-6.572604436000001,-5.912687087999999,-7.925654701,-8.041247398,-5.494071762000001,-5.489361229,-4.8391280210000005,-4.393586076,-1445.3239641180262 -1476,1476,V101S,0.025896471,-0.047804625,-0.047244324000000004,0.002169952,-0.734571924,-0.12468245300000001,-0.018641537,0.07043447900000001,0.043303815999999995,-0.04302991900000001,-0.05257933099999999,-0.031036242000000002,-0.063452406,-0.034332088999999996,0.038671992,-0.690441106,-0.7787027409999999,1.0175741409999999,1.482115366,-5.707502646,-5.347594399,-5.169382431,-5.959848465,-6.1121203,-5.948567635,-4.457939644,-2.300164485,-1444.0989138544537 -1477,1477,V101R,-0.029726575,-0.071618527,-0.06318036099999999,-0.047036554,-0.498956704,-0.097602212,-0.056275436,-0.0031777140000000003,0.002532095,-0.072453217,-0.070783837,-0.026240007000000003,-0.100120714,-0.054944090999999994,-0.039129016,-0.49515197899999996,-0.502761429,1.366071089,1.752833536,-5.432205493,-3.78891935,-6.812360054,-5.793337417999999,-3.743504906,-7.022905739,-4.296788008,-2.98782462,-1443.2154060169123 -1478,1478,V101T,0.019684723,-0.012713367,-0.018160093999999998,0.007474944,-0.118362671,-0.110620274,-0.0020525929999999997,0.041422038,-0.018321086,0.01312904,-0.038555774,0.066667486,-0.102987674,0.0037529940000000004,0.011196893000000001,-0.12877002699999998,-0.107955315,1.2507182479999999,2.1352310919999997,-4.827128206,-4.22329908,-3.573408829,-5.426389747999999,-4.878798126,-6.033745247000001,-3.597625433,-1.59421207,-1452.6639259443618 -1479,1479,V101W,-0.118609412,-0.085934709,-0.129582387,-0.27201754100000003,-2.291497139,0.13253715300000002,-0.17724783600000002,-0.059970987,0.10115811300000001,-0.07355316099999999,-0.09831625599999999,-0.076364138,-0.18280063600000002,-0.15946779,-0.38456729100000003,-1.996969896,-2.5860243819999997,1.176680558,1.321391186,-9.296819786,-7.964083351,-9.725465446,-9.787296547,-8.687521454,-10.31973213,-6.320729172999999,-5.48555408,-1462.4773934525438 -1480,1480,V101Y,-0.023634122,-0.052784914,-0.021404766000000002,0.002228609,-1.5029203580000001,-0.023810401000000002,-0.051837695999999996,0.004569452,-0.028127705,-0.031355481,-0.074214346,-0.015984963999999997,-0.026824567,-0.011095421999999999,0.01555264,-1.7713858740000001,-1.234454842,0.653236191,1.306784194,-9.572959401,-8.212651512,-11.42275547,-10.31059773,-7.713855865,-10.20493642,-6.376426021,-2.666014004,-1449.0216840705834 -1481,1481,E102A,0.009324818,-0.011267963,-0.040806359,-0.001681521,0.016406132,0.093191201,0.017112309,0.0015373270000000002,-0.057500062000000005,0.015545413000000001,-0.038081339,0.007226318000000001,-0.088839036,-0.009789404,0.006426362,0.088845584,-0.05603332,1.139982465,2.831820233,-1.343915956,-1.8154311980000002,-1.3435783000000001,-1.120621513,-1.862148422,-0.577800346,-2.498388331,0.12264348,-1460.3552232761867 -1482,1482,E102C,0.03817808,0.020783745,-0.009173915999999999,-0.294042918,-1.752428509,0.075337212,0.026616461,0.049739698,-0.06698461900000001,-0.043643462,0.08521095199999999,-0.046044697999999995,0.027696866,-0.217896912,-0.370188924,-1.515160298,-1.9896967190000001,1.341388528,1.405567536,-8.232932544,-8.797414162,-8.187144607999999,-7.543496971000001,-9.597824142,-7.038782837,-8.841266829,-7.868517891000001,-1462.923052211292 -1483,1483,E102D,0.084501334,-0.037281977,-0.01120785,0.0032559959999999997,-0.0029742379999999997,-0.055364285,0.053865706,0.115136962,-0.073139913,-0.099188284,0.02462433,-0.037955762000000004,0.015540062,-0.039662496,0.046174487,0.027913937000000003,-0.033862413,1.132670201,2.661337655,-0.674036978,-0.819597687,-0.674686943,-0.331117676,-1.7168140490000001,0.172031464,-2.208766519,0.354471828,-1461.8439484243281 -1484,1484,E102G,0.040304391,-0.020944637,-0.044042417,-0.007946243,-0.29465882,-0.090591265,0.031969668,0.048639113,-0.04062282,-0.042781599000000003,0.000892325,-0.025419334,-0.062665499,-0.034307755,0.01841527,-0.21390542699999998,-0.375412213,1.320039096,2.004616634,-4.315171599,-4.054072456,-3.9234917680000003,-3.124240349,-7.553096039,-2.920957382,-3.8058492289999997,0.6926375020000001,-1460.0767190721817 -1485,1485,E102F,0.047593372,-0.031544983,-0.024743712,-0.00882471,-0.08769159900000001,0.118680762,0.011223055,0.08396368800000001,0.063358804,-0.123857767,0.060767802,-0.076738442,0.027251018,-0.03673505,0.01908563,-0.07633884,-0.09904435699999999,1.277959855,2.292871582,-7.0934793439999995,-10.14669139,-7.010332642000001,-5.680098984,-7.00747506,-5.622798645,-5.300078281,-2.251818605,-1463.7441299487837 -1486,1486,E102I,0.008491857,-0.04983913,0.023612084,-0.022212045,-0.09800573800000001,0.29117825399999997,0.0033915959999999998,0.013592116999999999,0.098993168,-0.097017765,-0.002660495,-0.00495163,0.052175797999999995,0.010456719,-0.054880807999999996,-0.049956985999999995,-0.14605449,1.232510956,2.4574268790000002,-6.386460905,-8.307892403,-4.518826889,-4.512192841,-8.962811745,-5.63058065,-5.655494227,-2.288066357,-1459.682373008225 -1487,1487,E102H,0.01640576,-0.044646385999999996,-0.083456721,-0.095656738,-0.068771438,0.075979735,-0.010922683999999998,0.043734204000000006,0.155856864,-0.103943101,0.014650328999999998,-0.067147861,-0.09976558,-0.11478117300000001,-0.076532302,-0.018109408,-0.119433468,1.349850147,2.429634139,-5.48800166,-5.051740532,-5.630500641,-4.86459774,-7.052422622999999,-4.840746765,-5.093037183,-3.233006899,-1464.6162925595418 -1488,1488,E102K,0.06217737,-0.013209647,0.051156691,0.02096043,-0.062874373,0.57346682,0.057277157999999995,0.067077582,-0.154563648,-0.031005948,0.004586655,-0.07353330200000001,0.175846683,-0.039458937,0.08137979599999999,-0.04779888,-0.077949865,1.5464736069999998,2.938183126,-2.890925082,-2.715477615,-3.0552623139999997,-3.095536133,-2.9459838260000004,-2.642365524,-2.753194389,-1.256679882,-1455.090524691157 -1489,1489,E102M,0.031540671,-0.04680941,-0.078978543,-0.013850513,-0.062337675999999995,0.36895036700000006,0.018357915,0.044723426,0.038115748,-0.068310857,-0.025307963,-0.067710183,-0.090246903,-0.023413062000000002,-0.004287964,-0.007049118,-0.11762623400000001,1.223079145,2.5155720169999998,-7.317632324,-8.891729172,-6.44075914,-6.26672892,-8.594620201,-6.394324188,-5.6845199939999995,-3.388936278,-1459.1335722766817 -1490,1490,E102L,-0.006275741,-0.010432165,-0.057204765,-0.038738426,-0.06177225,0.18268347100000001,-0.034371565,0.021820082999999997,-0.038022214,-0.039957769,0.019093439,-0.03753098,-0.07687855,-0.034852693,-0.042624159,-0.009280985,-0.11426351400000001,1.209166103,2.536844099,-6.510111387999999,-7.429902374,-5.6967720029999995,-5.688899848999999,-8.347153587000001,-5.387829124,-5.64632106,-1.225266268,-1454.1988693363965 -1491,1491,E102N,0.012213955,-0.045907116,-0.049959262000000004,0.006167113,-0.08630534699999999,0.069316667,-0.07063747299999999,0.095065383,0.296111112,-0.048221802,-0.043592429,-0.018143727,-0.081774797,0.000398714,0.011935511999999999,-0.015796712,-0.156813982,1.184187625,2.515322054,-3.3145106089999996,-3.437925491,-3.17030925,-2.581079033,-4.781284988,-2.601954285,-4.727050118,-1.206964237,-1465.9678198308684 -1492,1492,E102Q,0.02061284,-0.004829368,-0.063993284,-0.020900025,-0.045655707999999996,0.145492132,-0.014632137,0.055857817000000004,-0.059044065,-0.022341431000000002,0.012682695,-0.056801164,-0.071185403,-0.06412864,0.02232859,0.029051498,-0.120362914,1.082345107,2.565519696,-4.386887163,-3.960969078,-4.304307701,-4.01247226,-5.473025573999999,-4.1836612010000005,-5.527484835,-2.043886294,-1463.7320030941628 -1493,1493,E102P,0.038249172000000005,-0.002460804,-0.022889627000000003,-0.019182979,0.007137683000000001,0.09211499599999999,0.012390265,0.064108078,-0.041275601,-0.04396840900000001,0.039046801,-0.044942734000000005,-0.000836519,-0.057885215,0.019519256999999998,0.032059817000000004,-0.017784452,1.2585913659999999,2.7027239410000004,-2.620635217,-2.9631420060000004,-2.3699873119999997,-2.9603210910000004,-3.099378342,-1.7103473359999999,-3.743732657,0.7482069440000001,-1458.562522161752 -1494,1494,E102S,0.05995079,-0.005103225,-0.001061905,0.001762195,0.012132849,0.14538905800000002,0.032424102999999996,0.087477477,-0.035802712,-0.027116631000000002,0.016910182,-0.01189591,0.009772101,-0.035596431,0.039120821,0.041468617,-0.017202919,1.083897781,2.677064204,-1.308189906,-0.650446152,-1.637133102,-1.280035049,-2.60889576,-0.364439468,-2.712106753,0.021227588999999998,-1466.976721727755 -1495,1495,E102R,0.013658168,-0.003216132,-0.053470786,-0.048473594,-0.112260649,0.34711543200000006,-0.010739465,0.03805580000000001,-0.036089128,-0.041510326,0.035078062,-0.06530898,-0.041632591000000004,-0.07519330099999999,-0.021753886,-0.085959189,-0.13856210800000002,1.426699217,2.364769258,-4.314601163,-4.751068985,-3.52405098,-4.108197594,-6.120448586,-3.06923967,-5.290723528,-1.5088251719999999,-1454.1942804390565 -1496,1496,E102T,0.018578095,-0.036185839,-0.050671618,-0.027174231,-0.019363092,0.101853035,-0.015841258,0.052997447,-0.003918902,-0.044475951,-0.027895727000000002,-0.029847345,-0.07149589099999999,-0.040464941000000004,-0.01388352,0.04698381,-0.085709994,1.272442665,2.77972392,-0.568495905,-1.162286949,-0.500584045,0.070184097,-1.269374565,0.01958194,-1.745315367,-0.099689136,-1477.9636530624703 -1497,1497,E102W,0.039110305,-0.040687855,-0.07582353900000001,-0.0267243,-0.754648517,0.17349794300000002,0.009531412,0.06868919700000001,-0.058809470999999995,-0.09510489400000001,0.013729185,-0.059090141,-0.09255693599999999,-0.102768496,0.049319897,-0.607386987,-0.9019100459999999,1.08192449,1.5819141540000001,-8.513880128,-10.29420113,-8.831783478,-7.270202133,-9.254826851,-6.918387054,-6.9873228329999995,-4.608140957,-1463.5105733275414 -1498,1498,E102V,0.004545399999999999,-0.002425635,-0.0346032,-0.028692036,-0.013551253999999999,0.152050241,-0.029428149,0.038518948,-0.037302743,-0.04292256,0.03807129,-0.025311912000000002,-0.043894487999999995,-0.046921207,-0.010462865,0.034172925,-0.061275432000000005,1.201001598,2.6734840859999998,-4.096636218,-5.643042847,-1.81495919,-2.92001326,-6.355567252999999,-3.749598541,-4.046628611,-1.160749028,-1457.0905148494057 -1499,1499,E102Y,0.046666955999999996,0.026181052000000003,0.01925528,0.0632316,-0.043454595,0.11932593400000001,-0.007183131999999999,0.100517044,0.01897743,0.017599386,0.034762718,0.01061948,0.02789108,0.023395332,0.103067868,0.032808621,-0.119717811,1.1443711540000001,2.808825171,-6.80886499,-8.305018318,-6.945234612,-5.4005653229999995,-7.673615402,-5.719891296,-5.347930821,-2.396955138,-1463.9248740081675 -1500,1500,Y103A,-0.03559329,-0.048070527,-0.01945544,-0.051418075,-1.550650111,-0.070933509,-0.099982864,0.028796285,-0.08289929900000001,-0.027657957,-0.068483097,-0.01684759,-0.02206329,-0.007364113,-0.095472037,-1.65569067,-1.4456095519999999,0.849189535,1.323058377,-10.58668431,-8.32005513,-11.64706407,-10.15951344,-10.90376273,-11.90302619,-6.153452581,-2.214940636,-1433.636727414094 -1501,1501,Y103C,-0.031449683,-0.004988079,-0.013592198,-0.243704384,-1.8546371480000001,0.012208953,-0.066108271,0.0032089059999999997,-0.108491886,0.016853728999999998,-0.026829887,-0.007170897,-0.020013498,-0.24748156,-0.239927207,-1.733519566,-1.9757547290000002,0.5491867420000001,1.302912209,-11.38701479,-11.72793298,-12.8054844,-10.54441958,-12.32794434,-9.529292671,-8.146801337000001,-3.991393758,-1451.4310068194754 -1502,1502,Y103E,-0.037127772999999996,-0.054230348,-0.10429649699999999,-1.571789792,-2.177651822,-0.034278309,-0.075840503,0.0015849570000000001,0.144534293,-0.060238365999999995,-0.048222329,-0.043725809000000004,-0.164867184,-1.3543603869999998,-1.789219196,-2.193434828,-2.161868815,0.69862739,0.714720758,-11.80405332,-9.769531105,-14.57684316,-10.9264632,-12.14618439,-11.60124477,-7.117992200000001,-3.8632711719999997,-1444.1464197002351 -1503,1503,Y103D,-0.048571813,-0.051599948,-0.029027702000000002,-1.193106894,-2.22642002,-0.06489756599999999,-0.071144424,-0.025999202000000003,-0.037141808,-0.08915442900000001,-0.014045466000000001,-0.034058468,-0.023996935,-0.981147274,-1.405066514,-1.934761217,-2.5180788219999997,2.3347989680000003,1.642784759,-10.99473507,-9.986297546,-12.34714725,-9.618599854,-10.80920096,-12.21242976,-6.502266979,-2.8068862660000002,-1439.225039544981 -1504,1504,Y103G,-0.006398069,-0.033022067999999995,-0.011694527,-0.002136913,-1.5459105430000002,-0.071113114,-0.05603484,0.043238702000000004,-0.10568393699999999,-0.054181907,-0.011862228999999998,-0.017628366,-0.005760688000000001,-0.000602284,-0.003671541,-1.48655636,-1.605264726,0.6912788129999999,1.3205065740000002,-9.984625732000001,-7.996547371,-12.79886829,-7.766943932,-11.00894549,-10.35182359,-6.055454284,0.254467632,-1432.9662129404023 -1505,1505,Y103F,-0.045050735999999994,-0.041058297,-0.044771949000000005,-0.034330937,-0.238752093,-0.022781127999999998,-0.06694679,-0.023154681,-0.074633618,-0.056662684000000005,-0.02545391,-0.050134097999999995,-0.039409799,-0.07701000000000001,0.008348125999999999,-0.244799734,-0.232704452,1.199372656,1.9343194019999999,-5.768057954,-6.4995058210000005,-6.101388039,-5.32119944,-6.51408326,-4.4041132130000005,-6.009323404,-3.106451295,-1457.43311075354 -1506,1506,Y103I,-0.147854871,-0.09985103,-0.068676027,-0.764696548,-1.6357210290000002,-0.006047783,-0.178659375,-0.117050366,0.018483406,-0.09750506099999999,-0.10219699900000001,-0.049491337999999996,-0.08786071599999999,-0.493271355,-1.0361217409999999,-2.005761697,-1.265680361,1.6911397519999998,1.386271377,-11.30654185,-8.648484047,-12.92415092,-11.10504298,-11.55747438,-12.29755692,-7.217696664,-3.521978162,-1442.8337514423765 -1507,1507,Y103H,-0.016535564,-0.00847579,-0.016529294,0.01321681,-0.782617213,-0.011871137,-0.017445498,-0.01562563,0.056904851,-0.0434239,0.02647232,-0.039347923,0.0062893359999999995,0.010275873,0.016157747,-0.67372613,-0.891508295,0.613258414,1.381434036,-3.808133841,-3.47374173,-5.321738358,-3.615427513,-3.204600006,-3.4251615980000003,-4.120502916,-0.90385354,-1446.0297511233948 -1508,1508,Y103K,-0.069037223,-0.113006186,-0.553997919,-1.871682074,-2.536416425,-0.018804023,-0.127481271,-0.010593173999999999,-0.077604858,-0.117575044,-0.10843732800000001,-0.52075424,-0.587241597,-1.5583683080000001,-2.18499584,-2.73703614,-2.33579671,1.954938064,0.988051508,-11.28729712,-10.58492824,-12.92426598,-10.82130459,-11.63867317,-10.4673136,-8.318440212999999,-5.258716045,-1446.649851217866 -1509,1509,Y103M,-0.0053095040000000005,-0.023037357,0.024612126,0.009628693,-1.746080843,-0.082411258,-0.024730126,0.014111118,0.06069784,-0.005694070999999999,-0.040380643,0.008437576,0.040786675,0.015908195,0.0033491909999999996,-1.427160737,-2.0650009480000002,0.562446154,1.317175385,-12.20713058,-10.73150129,-12.95494767,-11.89488287,-12.90501578,-12.54930528,-8.724300107000001,-5.714755152,-1435.8885449445806 -1510,1510,Y103L,-0.087192536,-0.06105568,-0.031958366,-0.7956643290000001,-1.681825516,-0.027080824,-0.118948573,-0.05543649900000001,-0.015239967,-0.068464047,-0.053647312999999995,-0.024847422999999997,-0.039069308999999997,-0.580260711,-1.011067946,-1.8581998709999998,-1.5054511609999999,1.8607973269999998,1.472915086,-10.40651469,-9.098682419,-10.59733482,-10.39720757,-10.96252936,-10.97681927,-7.661885487999999,-4.341591415,-1428.2730230335146 -1511,1511,Y103N,-0.08645297699999999,-0.036985252999999996,-0.036149186,-0.010693496,-1.2467469999999998,-0.024792718,-0.123005756,-0.049900198,0.008723568000000001,-0.037613602999999995,-0.036356902,-0.024810927000000003,-0.047487445,0.056794352,-0.078181343,-1.214824002,-1.278669997,0.747634137,1.342288318,-7.378222765,-6.824054535,-9.145194984,-5.81346492,-6.776937836,-8.331461548,-4.472886572,-1.503383158,-1448.923585487064 -1512,1512,Y103Q,-0.043592799,-0.045826657,-0.03952644,-0.354801926,-1.936924464,-0.03371773,-0.075265659,-0.011919938,-0.027274085,-0.045574512000000005,-0.046078800999999996,-0.015686443,-0.063366436,-0.21147502,-0.498128832,-1.96167779,-1.9121711369999999,1.20062038,1.324761023,-11.90304338,-11.52050692,-13.53723603,-11.38730995,-11.38933994,-11.68082406,-9.067966532,-6.075925448,-1439.7757092807442 -1513,1513,Y103P,-0.004184865,-0.061144263,-0.001596155,-0.029937283,-1.125442206,-0.057069363,-0.037174275,0.028804546,-0.068514641,-0.05106669,-0.071221836,0.015367712,-0.018560021,-0.034395245,-0.025479321,-0.966082843,-1.284801569,0.7074249029999999,1.359969576,-10.83940805,-7.163017395,-12.33770146,-10.80043841,-11.78328873,-12.11259427,-6.30387546,-1.7817100909999999,-1446.0787557731383 -1514,1514,Y103S,-0.058107825,-0.076590034,-0.034134028,-0.039833439,-1.620639579,-0.032681068,-0.09996706,-0.016248589,0.035581861,-0.062493145,-0.09068692199999999,-0.035083324,-0.033184731,-0.011338403,-0.068328474,-1.4553269180000001,-1.785952239,0.7247356009999999,1.3248540290000002,-9.63598418,-8.463795852999999,-10.24886179,-8.527913765,-10.41395418,-10.52539531,-6.319579688999999,-2.09117894,-1441.8535289959982 -1515,1515,Y103R,-0.02028246,-0.043373997000000004,-0.07010619400000001,-1.464283561,-1.838422416,-0.00010453200000000001,-0.077301829,0.036736909,0.00109809,-0.031883117999999995,-0.054864875,0.00035080800000000003,-0.140563195,-1.184431568,-1.7441355530000002,-1.9894081319999999,-1.687436699,2.458354126,1.6572561719999999,-10.73542044,-11.03280269,-12.70386889,-10.13294577,-10.26699504,-9.54048983,-7.799677558,-3.983543603,-1442.9134133411571 -1516,1516,Y103T,-0.010662201999999999,-0.034830394,0.027119002000000003,-0.119636277,-1.557550548,0.012957308,-0.049716582999999995,0.028392179,0.103219487,-0.031605951,-0.038054836,0.064439774,-0.01020177,-0.051320695,-0.187951858,-1.5793232030000002,-1.5357778930000001,0.7529334459999999,1.320191275,-10.97757031,-8.37180751,-12.24469241,-10.87271519,-11.45687282,-11.9417636,-6.223895613,-2.6577404280000003,-1440.6039678105153 -1517,1517,Y103W,0.026650333,-0.013341438,-0.015070132,0.002494321,0.054448019,0.217568471,-0.000215424,0.053516089,-0.148062535,-0.045086637,0.018403762,0.005861089,-0.036001353,-0.054417487,0.059406127999999996,-0.017988183999999997,0.126884222,1.335850987,2.63641595,-2.7808762939999996,-2.692244591,-2.950314125,-2.1908714369999998,-3.0442573389999996,-3.026693977,-3.139830358,-1.06000399,-1455.952604853548 -1518,1518,Y103V,-0.044995515,-0.029783702000000002,-0.043812507,-0.06333829,-1.5513143180000002,-0.055253764000000004,-0.094090319,0.004099289,-0.005829544,-0.024153359,-0.035414045,-0.039152383,-0.048472630999999995,-0.014757913000000001,-0.111918667,-1.576667665,-1.525960971,0.729236708,1.320133166,-10.54808046,-7.623221611,-12.24046948,-10.05284627,-10.56325972,-12.260605199999999,-6.430711591000001,-3.203959217,-1444.7132896301337 -1519,1519,S104A,0.035921052,0.018118762,0.017096871,-0.014351967,-0.593591064,0.068802933,0.027193207,0.044648895999999993,,0.000480532,0.035756992,0.019745831999999998,0.01444791,-0.052625741,0.023921808,-0.419099723,-0.768082404,1.313633597,1.7757726459999998,-4.2707539610000005,-4.417247551,-3.2077956239999996,-2.497953743,-6.3821848139999995,-4.848588073999999,-4.321525992,-1.355635287,-1454.1655381601304 -1520,1520,S104C,0.035432832000000004,-0.015412063,-0.0197801,-0.098731414,-1.841876679,0.0340079,0.03818072,0.032684944,,-0.003788885,-0.027035241,-5.94e-06,-0.039554259,-0.045515719,-0.151947108,-1.8190314440000002,-1.8647219130000001,0.80679212,1.310245976,-10.84921473,-14.95272893,-10.73463311,-8.579851265,-11.2325713,-8.74628907,-9.480809609,-4.659014078999999,-1459.048672308214 -1521,1521,S104E,-0.027544314,-0.409092289,-1.571020499,-2.2332709790000003,-2.979643612,0.041909208999999996,-0.030372099,-0.024716527999999998,,-0.314545848,-0.50363873,-1.5286598919999999,-1.613381105,-2.09224261,-2.374299347,-2.555991576,-3.4032956469999998,2.8861150319999997,1.184170041,-10.75390518,-12.96542772,-9.28160685,-9.463875977,-11.23250611,-10.82610926,-8.530517577000001,-3.949012306,-1455.8899396802299 -1522,1522,S104D,0.15883012400000002,-0.081482351,-0.389089631,-1.7840360240000002,-2.486833569,0.029174325,0.182312962,0.13534728599999998,,-0.020651869,-0.142312833,-0.23101442600000002,-0.547164836,-1.545955218,-2.0221168290000002,-2.524613999,-2.449053138,1.305800654,0.774063955,-11.26543315,-15.55046043,-10.29189278,-9.129799538,-12.32193037,-9.033082634,-8.457585883,-3.822061935,-1443.3192390310578 -1523,1523,S104G,-0.0060993869999999995,0.001299559,0.023508868,-0.026190725,-1.652025149,0.059986738,-0.013330345,0.001131572,,0.028201469,-0.025602352000000002,0.021306734,0.025711001,0.0062181580000000005,-0.058599607000000005,-1.621801901,-1.682248397,0.464646141,1.304798765,-9.557354655,-12.44395766,-9.156423271,-8.626318481,-9.400219627,-8.159854232999999,-8.079238568,-2.2356804390000002,-1435.893770863302 -1524,1524,S104F,-0.18563390899999999,-0.199477848,-0.503831788,-1.773839444,-2.326121992,0.031715686,-0.169869556,-0.201398262,,0.002994447,-0.401950143,-0.159468745,-0.8481948309999999,-1.525562059,-2.0221168290000002,-2.203190845,-2.449053138,1.024732693,0.7361813970000001,-12.64700634,-17.74628269,-13.21569376,-10.16850558,-11.77845152,-10.32609816,-8.277692576,-4.703870248,-1457.8618289851584 -1525,1525,S104I,-0.047671754000000004,-0.022634931,-0.964136742,-1.57694742,-1.89066934,-0.027957764,-0.057447377,-0.03789613,,0.075853672,-0.121123534,-0.816837218,-1.111436266,-1.608899265,-1.544995574,-1.809406796,-1.971931883,4.289146126,3.162138117,-13.418027599999999,-18.20587504,-14.84675288,-10.45207081,-11.6412735,-11.94416579,-9.300101527,-4.338774572,-1449.9297101860866 -1526,1526,S104H,0.035223129,0.03480024,-0.11292147400000001,-0.061958087,-1.905650951,-0.001791635,-0.080928473,0.15137473099999998,,0.065785277,0.003815203,-0.24474045,0.018897502,-0.191704457,0.067788283,-1.839370019,-1.971931883,1.2538382190000001,1.342705562,-12.21860896,-16.61524598,-11.15589542,-9.581099411,-11.61285402,-12.12794998,-9.616698566,-5.833198987,-1453.1614916673861 -1527,1527,S104K,-0.04281585,-0.008242985999999999,-0.45451961399999996,-1.8191688999999998,-2.464994769,0.046201794000000004,-0.042400784000000004,-0.043230915,,-0.005719175,-0.010766797,-0.28082681600000003,-0.628212412,-1.465976369,-2.172361431,-2.7456651460000003,-2.184324391,1.430574311,0.818752413,-12.17016467,-15.70732791,-9.583916588,-10.33060951,-12.29037216,-12.93859717,-10.65068302,-6.950523036,-1454.5367474379018 -1528,1528,S104M,-0.018705375,0.019315543,-0.36639478700000006,-1.6522047480000002,-2.537879956,0.012366938000000001,-0.019045202,-0.018365547,,0.026327772000000003,0.012303313,-0.208517591,-0.524271983,-1.4526315980000002,-1.8517778980000001,-2.5240444319999997,-2.551715479,1.209853782,0.7692103840000001,-11.50950628,-15.27987972,-11.00421262,-9.434919487,-9.685558571,-12.14296103,-8.528150822,-5.104725364,-1458.6833944637328 -1529,1529,S104L,-0.06336159599999999,-0.86970304,-1.760762665,-2.220868606,-3.01316915,0.04296991,-0.06381616400000001,-0.062907027,,-0.788318249,-0.95108783,-1.766019929,-1.755505401,-2.162495872,-2.279241339,-2.683338554,-3.342999745,3.157004253,1.15204559,-13.86177729,-18.65491854,-13.40665779,-12.31385849,-12.47566051,-12.45779109,-10.076600099999999,-6.315680945,-1443.7314930581488 -1530,1530,S104N,-0.400913294,-0.036649293,-0.43066334700000003,-0.335987351,-1.206680947,0.244394077,-0.512292237,-0.289534351,,-0.107077012,0.033778426,-0.5737991689999999,-0.287527525,0.350142128,-1.022116829,-0.964308756,-1.449053138,0.307526788,1.321758068,-8.960142859,-13.09340082,-7.833773323,-6.174748207,-9.271837448,-8.426954497999999,-7.4400235189999995,-3.824945501,-1447.5897284015082 -1531,1531,S104Q,-0.033022956,0.0008697510000000001,-1.187447634,-2.158699108,-3.1117978280000003,0.061076492999999996,-0.01094754,-0.055098372,,0.024965585,-0.023226082999999998,-1.101259813,-1.2736354540000001,-1.8320522030000002,-2.485346012,-3.311313335,-2.912282321,2.3317608990000003,1.008100322,-10.278331699999999,-12.94771544,-7.769069839,-9.451548195,-9.524731232,-11.69859379,-8.712483701,-3.1117475239999997,-1446.8504967237823 -1532,1532,S104P,0.003832419,0.007738152,-1.156524794,-1.792250502,-2.4748801719999998,0.02312021,0.013706551,-0.006041714,,0.020601762,-0.005125458,-1.0734862520000001,-1.239563335,-1.7661636669999998,-1.818337336,-2.451761382,-2.497998961,2.781978492,1.4196419569999998,-10.82437539,-13.19598366,-10.20748555,-9.743901367000001,-11.35951141,-9.614994965,-8.36726091,-3.390519255,-1445.810488841962 -1533,1533,S104R,0.002650054,0.0022749289999999998,0.015895246000000002,-1.4876622080000002,-2.231699902,0.044020400999999994,0.002883609,0.002416498,,0.028431729,-0.023881871000000002,0.065062766,-0.033272274,-1.3046152709999999,-1.670709145,-2.240815613,-2.22258419,0.869032308,0.737209522,-13.51099261,-16.97633954,-12.99467189,-11.29788361,-11.99122461,-14.294843400000001,-9.662088652000001,-6.054136587,-1445.9244713219814 -1534,1534,S104T,-0.062068205999999994,0.004185731,-0.012210634,-0.08759826,-1.7230472909999999,0.064780043,-0.063639215,-0.060497195999999996,,0.069014247,-0.060642786,0.016403975,-0.040825242000000005,0.008462064,-0.18365858300000001,-1.6782826819999999,-1.7678118999999999,0.583197104,1.306520317,-7.192254016000001,-10.0346138,-6.175500626,-4.8805513760000006,-7.205511215,-7.665093063,-7.429014361,-1.908054045,-1447.264111711178 -1535,1535,S104W,0.02055038,-0.273629117,-1.45511843,-2.01250698,-2.463579428,0.044775612,0.022482069,0.018618691,,-0.222369467,-0.324888766,-1.536010609,-1.3742262509999998,-2.053371598,-1.9716423619999999,-2.679847861,-2.247310995,2.689127978,1.051204027,-15.0361096,-20.269728399999998,-15.45347575,-13.09120722,-13.43962217,-12.92651444,-9.694247609,-4.4334584580000005,-1459.0131457271054 -1536,1536,S104V,-0.023832545,0.011478471,0.038511949,-1.476238065,-2.203338277,0.042430237,-0.011585763999999998,-0.036079326,,0.013594938,0.009362003,0.063768818,0.01325508,-1.24213729,-1.710338839,-2.372063747,-2.0346128059999997,0.329774976,0.7011623229999999,-13.03162991,-16.17375417,-14.94351566,-10.42150915,-11.68589626,-11.93347433,-8.990094367000001,-4.895315078,-1448.7185872434638 -1537,1537,S104Y,-0.081882709,0.0079623,-0.16598291099999998,-1.4777635930000002,-2.140970515,-0.020740685,-0.035170982,-0.128594436,,0.15823743199999998,-0.142312833,-0.07440152,-0.25756430199999997,-1.167493562,-1.788033623,-2.0669710980000002,-2.214969932,2.349526989,1.5664599259999998,-14.07012977,-18.81313107,-15.26193134,-10.65555508,-12.76551349,-12.85451786,-9.184094847,-5.4861321720000005,-1457.592095931992 -1538,1538,P105A,-0.01793208,0.008901083,-0.040817482999999995,-0.018949929,-1.6179086969999998,0.021493397,-0.029878114,-0.005986046,0.0008598869999999999,-0.010356597,0.028158763,-0.06274459,-0.018890375,-0.011694649,-0.026205209,-1.792601219,-1.443216175,0.653236191,1.306784194,-8.183916423,-8.63088575,-9.11003083,-10.44609914,-8.430067252999999,-4.302499138,-5.997965991,-3.330149169,-1442.1523362006992 -1539,1539,P105C,-0.003247222,-0.027213308,-0.156932129,-1.693777268,-2.263977654,0.066878325,0.027371267,-0.03386571,0.04389451900000001,-0.031578237,-0.022848379,-0.089038675,-0.224825582,-1.517709711,-1.869844825,-2.855021585,-1.6729337219999998,0.856676489,0.7147178590000001,-14.88022422,-14.70212283,-14.73780418,-17.87968893,-14.76103816,-12.320466999999999,-10.61968155,-9.88449642,-1459.500568070449 -1540,1540,P105E,-0.004942236,-0.050056475999999996,-0.009415334000000001,-0.036943107,-1.507607725,0.030061054,0.019804276000000003,-0.029688747999999997,0.064515055,-0.096569729,-0.003543223,-0.006279066,-0.012551601,-0.001497794,-0.07238841900000001,-1.5834356319999998,-1.4317798169999998,0.606928577,1.312592777,-10.54013443,-10.52849612,-11.07244686,-13.268897,-10.28899707,-7.541835121,-7.016667927,-3.967445298,-1449.4524181922898 -1541,1541,P105D,-0.048215585,0.07212915,-0.034812273,-0.8626459040000001,-2.270477617,0.050233417,-0.011999425,-0.084431744,0.010327171999999999,0.014818333000000001,0.129439966,-0.06967414599999999,4.96e-05,-0.49226908,-1.233022727,-1.816868989,-2.7240862439999995,1.768289681,1.463445281,-10.89308444,-11.15907339,-11.16458569,-13.01095358,-11.46224634,-7.668563187,-6.594177009,-3.079261978,-1451.9094267245382 -1542,1542,P105G,0.008789975,0.010468704,-0.026467088,-0.425160692,-1.889083431,0.022891032999999998,0.013724921999999999,0.003855028,0.02270522,-0.006954765,0.027892173,-0.007628245,-0.04530593,-0.237995142,-0.612326241,-1.6710809580000001,-2.107085903,1.313787267,1.3714449180000001,-12.00755628,-12.47442097,-12.92191518,-15.30946496,-11.75772208,-7.574258202,-6.851037865,-0.630004765,-1447.091745402664 -1543,1543,P105F,-0.015090107,-0.027415165,0.023680786000000002,-0.095615566,-2.0273263480000003,0.025645585,0.002295461,-0.032475673999999996,-0.043255655999999996,-0.038697978,-0.016132351,0.032162752999999995,0.015198818000000001,-0.039661467,-0.151569665,-1.884984809,-2.1696678869999997,0.8318095940000001,1.307575097,-14.26118269,-13.59833581,-13.978176199999998,-17.97867885,-14.02339073,-11.72733187,-8.565743591,-6.298960888,-1463.314096315764 -1544,1544,P105I,-0.008752117,-0.012170381999999999,-0.001040544,-0.034353356,-1.902309225,-0.008400742,0.00365764,-0.021161872999999998,0.08168308,-0.08863103300000001,0.06429027,0.019534354,-0.021615442000000002,0.0032592429999999998,-0.071965954,-1.38472072,-2.419897729,0.768160347,1.3320777,-12.55220648,-12.70648557,-12.95246433,-16.00149257,-11.62581812,-9.474771797,-7.561118542999999,-4.414047246,-1457.4786817892455 -1545,1545,P105H,-0.034821038,-0.06362712400000001,-0.08286858,-0.058331701,-1.607758802,0.060519002,-0.014137245,-0.055504831,-0.078896013,-0.068193696,-0.059060550999999996,-0.10008114800000001,-0.065656012,-0.032536578,-0.084126823,-1.5599545369999999,-1.655563066,0.848508299,1.327273592,-13.24771158,-13.52739177,-13.37306887,-15.76852309,-13.58653336,-9.983040802,-9.508189892,-7.090362469,-1458.3702087029815 -1546,1546,P105K,0.040550578999999996,0.00962138,-0.021786681000000002,0.037860859,-1.4479402959999998,0.045619462,0.0744963,0.006604857,0.155469294,-0.046635425,0.065878185,-0.013858568,-0.029714794,0.024146874,0.051574844,-1.662616879,-1.233263712,0.77572445,1.316325833,-10.23545316,-9.995317497,-10.48635027,-13.57657024,-9.324647857999999,-7.794379921,-6.650368512999999,-4.325334746,-1447.8365161954425 -1547,1547,P105M,0.122141858,0.04944902599999999,0.030785725,0.022184932,-1.9629404069999998,0.040343132999999996,0.155564595,0.088719121,0.044770997,-0.067716555,0.166614606,-0.032457401000000004,0.09402885,-0.06282062,0.107190484,-1.5896252069999999,-2.336255606,0.9101248279999999,1.3311503709999999,-13.82033204,-13.43462017,-13.77744794,-17.26417176,-13.09853311,-11.52688721,-9.179539672999999,-6.5140615120000005,-1456.1901081819087 -1548,1548,P105L,-0.000146894,0.024546652000000002,0.002379128,0.013450585,-1.565477837,-0.001078468,0.004017436,-0.004311223,0.127936624,-0.027172626000000002,0.07626593,-0.018925075,0.02368333,0.018861468,0.008039702,-1.4768918690000001,-1.654063804,0.5972854999999999,1.318263149,-11.96882571,-12.10523785,-11.78603197,-15.72969044,-10.91333083,-9.309837486000001,-7.408650284,-4.587375,-1455.3788302866742 -1549,1549,P105N,-0.083502704,-0.015762916000000002,-0.040035207,-0.22099803,-1.957567679,0.035630603,-0.053848966,-0.113156441,-0.178729064,-0.019346431,-0.0121794,-0.023561581,-0.056508832,-0.12832870400000002,-0.313667355,-1.823522141,-2.091613217,0.9691458279999999,1.3203851979999999,-12.71966361,-12.73664458,-13.02183746,-15.66556982,-11.96531635,-10.20894983,-7.638092331,-5.3953385879999995,-1452.5241098036058 -1550,1550,P105Q,-0.034140925,-0.031030927000000003,-0.04710361,-0.026478542,-1.620682791,0.063970795,0.028791631,-0.09707348,0.100166486,-0.024903144,-0.03715871,-0.033331187000000005,-0.060876032999999996,0.014467916,-0.067425,-1.6138897330000002,-1.6274758480000002,0.6504015360000001,1.312397861,-9.577311671,-9.445240051,-9.778481895,-12.07261974,-9.866071952999999,-6.7241447139999995,-6.588568177999999,-4.46282686,-1450.698063191492 -1551,1551,P105S,-0.040579613,-0.025237115,-0.033118125,-0.06258959,-1.694489614,0.024509592,-0.040606891,-0.040552335,0.011467551999999999,-0.00017398900000000002,-0.050300240999999996,-0.019973372,-0.046262877,-0.024961666,-0.10021751300000001,-1.698921395,-1.690057832,0.831963219,1.318474828,-9.712549828,-9.962574844,-9.112677452,-12.19323353,-9.532037682,-7.762225632000001,-6.640053631000001,-3.651936122,-1440.0107334777713 -1552,1552,P105R,0.045418584000000005,0.01942966,0.016155349,-0.044201782,-1.6710997090000002,0.039525246,0.068929411,0.021907756,-0.048650688,-0.047185310999999994,0.08604463,-0.045853353,0.07816405,-0.050417022,-0.037986541,-1.681403824,-1.660795593,0.8207807220000001,1.318541315,-10.10178597,-9.360484497,-10.90127403,-13.17317694,-10.43359133,-6.640403046,-7.351476984,-4.6064639739999995,-1451.7219035639428 -1553,1553,P105T,0.014060598,0.038445465,0.061955485,0.03068217,-1.455280832,0.056494915,0.012057018999999999,0.016064177,0.038217387,-0.023514036000000002,0.100404965,0.05708936,0.06682161,0.070491659,-0.009127319,-1.718134206,-1.192427458,0.5819789879999999,1.304089222,-10.24096958,-10.31091234,-9.775470108,-13.49628687,-10.07843818,-7.543740417,-7.4750709429999995,-2.9609316989999996,-1447.768636615947 -1554,1554,P105W,0.032360781,-0.055141447999999996,0.02921437,-0.731199387,-2.167596652,0.04794837,0.052428750999999996,0.012292811,-0.011873291000000001,-0.029638052,-0.080644843,0.003866653,0.054562085999999996,-0.41803907700000004,-1.044359696,-2.135562193,-2.199631111,1.6575167030000002,1.3511945719999998,-13.63342761,-13.10945093,-13.421378299999999,-16.37908466,-14.3500128,-10.90721134,-8.196340755,-5.569952545,-1464.726852080319 -1555,1555,P105V,-0.03579981,0.006636146999999999,0.0014376039999999999,0.014043222,-1.432323505,0.041421935,-0.046972917999999995,-0.024626701,0.046324825,-0.028337317999999997,0.041609611,0.012585421999999999,-0.009710215,0.001405051,0.026681392999999998,-1.365870046,-1.498776963,0.599050698,1.321589945,-9.777717067000001,-10.26856075,-10.84065807,-13.58177478,-9.254183716,-4.94340802,-5.993720357000001,-3.790407145,-1457.6319863176905 -1556,1556,P105Y,0.031035067000000003,0.0014041720000000002,0.023190147,-0.134138557,-1.3968637019999999,0.012416606,0.064431481,-0.002361348,-0.121560425,-0.038315298,0.041123641,0.0072918919999999995,0.039088402,-0.08627446400000001,-0.18200265,-1.666624387,-1.127103017,0.849128068,1.32312655,-15.22312528,-14.38848096,-15.70768102,-18.72192557,-15.12502209,-12.17251678,-9.505755045,-7.03838871,-1463.817769004032 -1557,1557,V106A,0.040560795,0.18978977800000002,0.05272310400000001,0.12201680699999999,-0.23832878300000002,0.014438517,0.040968802,0.040152787999999995,0.057991947,0.183870647,0.19570890800000001,0.09020624,0.015239967,0.140931052,0.103102562,-0.122624184,-0.35403338100000004,1.101621924,2.144464447,-5.701955237999999,-7.02722979,-4.338239243,-5.603826057000001,-6.840277832000001,-4.70020327,-5.424723595,-2.450906467,-1450.4598813569173 -1558,1558,V106C,0.095390719,0.18561348100000002,0.066945423,0.18316066399999997,-0.574227852,0.00959463,0.104850741,0.08593069699999999,-0.025554103999999998,0.16125362599999998,0.209973336,0.055599134,0.078291712,0.154393291,0.21192803600000001,-0.291523585,-0.856932118,0.576778308,1.495597345,-11.4135125,-12.19720108,-11.04635215,-11.60421555,-11.82806252,-10.39173122,-9.17493518,-6.285610929,-1459.3710853178054 -1559,1559,V106E,-0.045490607999999995,0.078293317,-0.013876798999999999,0.154010643,-0.040876561,0.069304225,-0.049999017,-0.040982199,0.192690521,0.096855484,0.05973115,0.001738438,-0.029492035,0.195882644,0.112138642,0.055850389,-0.13760351,1.118471852,2.9533257689999997,-7.372525443,-8.426553795,-4.822429672,-9.183023087,-8.542620766,-5.887999893,-5.094661904,-2.784845348,-1462.3263521594927 -1560,1560,V106D,0.018907755,0.14018281400000002,0.07019709,0.11972428199999999,-1.664693309,-0.011591976,-0.01952214,0.05733765,0.11489679800000001,0.192935816,0.087429812,0.013788284,0.126605896,0.13469857400000002,0.10474999,-0.6650040389999999,-2.664382579,0.489439367,1.363883,-10.54778447,-11.78373557,-7.638732864,-12.20328477,-11.33802912,-9.775140007000001,-8.058163798999999,-4.456255854,-1462.010832019616 -1561,1561,V106G,0.037119413,0.17474641,0.054450665999999995,0.11300327,-1.5154157730000002,0.014906618,-0.024547192000000002,0.098786018,0.086868075,0.195341885,0.154150935,0.073099206,0.035802125,0.19328009,0.032726449,-1.4389996330000001,-1.591831912,0.328642421,1.306471454,-8.318537059,-10.59705386,-5.633266159,-8.947756859,-8.463771027,-7.950837395,-6.675999319,-2.5362375530000003,-1459.0392469447106 -1562,1562,V106F,0.053303364000000006,0.101230158,0.032783343,0.078542269,-1.1384707809999999,-0.007803182,0.024480622999999996,0.082126105,0.054096902999999995,0.164477221,0.037983094,0.057388574000000005,0.008178112,0.14903748,0.008047057,-0.878593317,-1.3983482440000001,0.356557736,1.3317311729999999,-7.57816237,-9.437637642,-7.9231914670000005,-7.336012993,-7.450210274,-5.743759476,-6.735900841,-2.269551622,-1451.0608114646748 -1563,1563,V106I,-0.038204822,0.08512014300000001,0.036216752000000005,0.092675555,0.001953832,-0.006124785,-0.09843388900000001,0.022024246,0.04026318,0.09956983400000001,0.07067045200000001,0.032208235,0.040225269,0.174314049,0.01103706,0.082596406,-0.078688742,1.069397567,2.918971567,-1.928670465,-2.01879039,-1.325958763,-2.587385971,-1.627889198,-2.083328003,-3.036344123,-0.32733436,-1457.883659555111 -1564,1564,V106H,0.05111147,0.16640117699999998,0.060213377,0.10125576300000001,-0.99464539,0.049266485,0.019486581,0.08273635900000001,0.048121193,0.146213575,0.186588778,0.007686298,0.112740455,0.11788475300000001,0.08462677199999999,-0.818076881,-1.171213898,0.542891475,1.353302695,-11.70872025,-12.9881496,-10.76695895,-12.95914153,-11.91350249,-9.915848671000001,-8.589171902,-5.38961001,-1462.7391073522158 -1565,1565,V106K,-0.022416564,0.068244584,0.013801155,0.03255497,-1.2857219579999999,-0.043217035,-0.121342751,0.076509623,0.023229841,0.095368682,0.041120486,0.037916448,-0.010314138,0.044573633,0.020536306,-0.988820006,-1.58262391,0.538657146,1.340835155,-10.03726227,-11.63066222,-8.182264084,-10.59329633,-10.58338097,-9.196707748,-7.425147137000001,-4.480806335,-1457.8116809437051 -1566,1566,V106M,0.018275968,0.154644426,0.077251632,0.151870635,-0.066307304,0.0026703309999999997,0.000716339,0.035835596000000004,0.076475353,0.138574339,0.170714513,0.06357037900000001,0.090932885,0.173632552,0.130108718,-0.018783229,-0.11383137800000001,1.1133497190000001,2.638047589,-6.0580706410000005,-6.517654952999999,-4.64036293,-6.356912932999999,-6.285455025,-6.489967361000001,-6.449590132000001,-2.122691734,-1450.5343776345253 -1567,1567,V106L,0.06579748,0.120793762,0.054859487,0.109243264,-0.040586891,-0.022521454,0.024085374,0.10750958599999999,0.078859666,0.130599768,0.110987755,0.026873334,0.08284564,0.142274404,0.076212124,0.011156991000000002,-0.09233077199999999,1.212728392,2.8225668219999998,-4.591312445,-4.857283875,-4.498529448999999,-5.494381392999999,-4.183022606000001,-3.9233449019999997,-4.260422238,-1.00123857,-1444.0814824388362 -1568,1568,V106N,0.092335189,0.075597901,-0.002360615,0.15467567,-1.48746731,0.001060436,0.014133483,0.170536895,0.15241316,0.11169484699999999,0.039500955,-0.036228808,0.031507579,0.11195425199999999,0.197397087,-1.35644212,-1.6184925,0.620200026,1.32363291,-11.01460307,-12.41450238,-10.39368602,-11.37867662,-10.79963863,-10.086511699999999,-7.946479098999999,-4.270069712,-1461.4041220718063 -1569,1569,V106Q,0.035560325,0.14824673300000002,0.060772217999999996,0.108465892,-0.356222844,-0.006471353000000001,0.022079391,0.049041258,0.191679357,0.12427853,0.172214935,0.054275468,0.067268967,0.08089040900000001,0.136041375,-0.144747455,-0.567698232,1.321153482,2.238630195,-9.838776402,-10.8736351,-8.337720718,-11.14127032,-9.958999893,-8.882255974,-7.390567423999999,-4.7616395019999995,-1458.5570227783173 -1570,1570,V106P,0.022797027,-0.19078191600000002,-1.4618041609999999,-1.907458094,-2.620729962,-0.0022780020000000003,0.008832164,0.03676189,-0.01570408,-0.06470804599999999,-0.316855785,-1.4290291769999999,-1.494579144,-1.69198461,-2.1229315769999997,-2.317878725,-2.923581198,3.660230465,2.15179342,-11.15417601,-12.37912146,-9.915035973,-10.79244738,-12.06138328,-10.62289198,-8.573551377000001,-5.478402787,-1441.4403940606862 -1571,1571,V106S,-0.034340377000000005,0.108590195,0.010243626,0.083424601,-0.661677651,0.022091406,-0.07579789599999999,0.007117143,0.066721778,0.127936661,0.08924372800000001,0.018683155,0.001804096,0.12156485300000001,0.045284349,-0.44641912100000003,-0.87693618,0.571257879,1.419403244,-8.62546194,-9.891206687999999,-7.901045302999999,-7.785063843,-9.732408859,-7.817585007000001,-7.158087085,-2.683060737,-1450.71120993793 -1572,1572,V106R,0.086768315,0.127891355,0.030298517999999997,0.113624196,-1.148098026,0.044831746,0.08995515300000001,0.083581477,0.046410074,0.088886555,0.166896154,0.012933317,0.047663718,0.140662371,0.08658602,-1.1098636990000001,-1.186332352,0.61273723,1.337322484,-9.264624138,-10.62744516,-7.433961142999999,-10.2561225,-9.743552337999999,-8.262039551,-6.508300501,-3.4758065360000003,-1454.1211082828231 -1573,1573,V106T,-0.004166725,0.106082551,-0.014765833999999999,0.115543503,-0.284868942,-0.034643658,-0.021251434,0.012917985,-0.008954843,0.181032778,0.031132324,-0.010257981,-0.019273687,0.145199646,0.08588735900000001,-0.146097329,-0.423640554,1.3574336219999998,2.301876832,-6.204095334,-7.140181694,-5.3237036589999995,-5.8147351910000005,-7.298429619,-5.443426506000001,-6.224109532000001,-2.204239832,-1457.4520181166008 -1574,1574,V106W,-0.111445906,0.078158987,0.01277218,0.019560071000000002,-0.962883795,0.006305862,-0.146808215,-0.07608359599999999,-0.218214465,0.16117409300000002,-0.00485612,0.169597638,-0.144053279,0.157294513,-0.11817437199999999,-0.48785784200000004,-1.437909748,0.42523862,1.3818396240000002,-10.81550948,-12.79052549,-9.126807677999999,-11.26203549,-11.06705296,-9.831125771,-8.076518254,-4.633024309,-1457.2505757934414 -1575,1575,V106Y,0.028857358,0.095952232,0.051393241,0.12173597900000001,-0.819350791,0.034884699,0.007312598000000001,0.050402117,0.017874723999999998,0.164607268,0.027297196,0.05449699,0.048289492,0.195366255,0.048105702,-0.5116987510000001,-1.127002831,0.419289265,1.376233981,-9.286566808,-11.21969217,-9.678760376,-9.05721402,-8.415551308,-8.061616165,-7.091078836,-2.7373396480000003,-1456.1450682617724 -1576,1576,T107A,-0.006745241999999999,0.010280365,0.013892705,-0.046326133,-0.089299781,-0.026221223,-0.010337358,-0.003153125,0.036724017000000005,-0.032239185,0.052799914,0.018056459,0.009728951,-0.05004147900000001,-0.042610786,-0.046455530999999994,-0.13214403,1.412415236,2.5001693019999998,-3.9042093280000003,-4.29679451,-4.384091667,-2.63400798,-4.140134941,-4.06601754,-4.34101915,-1.28344751,-1455.2720513604581 -1577,1577,T107C,-0.046131949000000005,0.06085215099999999,0.023562797000000003,-0.006236448,-0.246232592,0.090840326,-0.06875782,-0.023506078,-0.10464663800000001,0.08510345300000001,0.036600848,0.091749735,-0.044624141,0.040800355,-0.05327325,-0.104049641,-0.388415542,1.191664345,2.182603877,-8.184400816,-8.692845314,-8.618500549,-7.138534439,-6.513374069,-9.95874971,-6.542029009,-4.333888698,-1466.5910511566326 -1578,1578,T107E,0.070681838,-0.631584843,-1.871881046,-2.0665628259999997,-2.6513373319999998,0.054069537,0.125920969,0.015442707,-0.065728571,-0.71560066,-0.547569026,-1.605759241,-2.13800285,-2.20330164,-1.929824011,-2.676197619,-2.626477045,2.91840322,1.046559996,-11.18889634,-11.18801355,-11.73426835,-10.21353255,-10.90371111,-11.90495614,-7.997672378,-5.417052637,-1461.8291272991337 -1579,1579,T107D,-0.029319077000000002,-0.58983647,-1.88319168,-2.301452476,-2.735711985,0.040869295,-0.024600092999999996,-0.03403806,-0.139157489,-0.657174635,-0.522498305,-2.360246573,-1.4061367869999999,-2.258818968,-2.3440859830000003,-2.731714947,-2.739709022,0.8326989379999999,-0.459474108,-10.77704053,-11.25618,-13.08950011,-9.836159431,-10.01746719,-9.685895897,-8.043100848,-4.503289572,-1462.4921608339064 -1580,1580,T107G,-0.08176576599999999,0.0040735979999999995,-0.018747262,-0.39933271,-1.84055421,0.047757680999999996,-0.072971643,-0.090559888,-0.134083124,0.012279334,-0.004132139,-0.005657985,-0.031836538,-0.17513722,-0.623528199,-1.997982837,-1.683125582,1.130332825,1.3133351709999999,-9.883430327000001,-10.46779593,-9.145671265,-8.780298225,-9.765120949,-11.25826527,-7.630179922000001,-3.528947717,-1462.2697145361453 -1581,1581,T107F,-0.052304069,0.06989519799999999,-1.102515441,-2.264042075,-3.0477865860000004,0.050149556,-0.015087841000000001,-0.089520296,0.118795855,0.051280162000000004,0.08851023400000001,-1.094313917,-1.110716964,-1.8621180309999998,-2.665966118,-3.033984015,-3.061589157,2.314948436,1.00319852,-10.96099193,-10.00413546,-13.30559003,-9.857818909,-8.631354546,-13.00606072,-6.666560358,-3.292247872,-1457.661503485404 -1582,1582,T107I,-0.038382055,0.011377337,0.01577585,-0.18761643600000003,-1.853374251,0.047886449000000005,-0.011256055,-0.06550805400000001,-0.040904987999999996,0.0012193269999999999,0.021535346,0.049542708,-0.017991008,-0.127972152,-0.247260719,-1.6836535019999999,-2.023095,0.964594829,1.330277399,-7.536819572000001,-6.877027892999999,-9.259155769,-6.864325478,-6.0935305479999995,-8.590058174,-5.366195426,-2.236196538,-1450.656508433167 -1583,1583,T107H,-0.15235711,-0.5895886920000001,-1.6006534680000002,-2.125854173,-2.992764396,0.020440643,-0.099608265,-0.205105955,-0.043452177,-0.555518187,-0.623659196,-1.552132099,-1.649174836,-1.965614309,-2.2860940359999997,-2.7017517239999997,-3.283777067,3.035158485,1.28948879,-13.29870722,-14.08022835,-14.36021736,-12.05296189,-11.68835439,-14.31177409,-8.190428629,-5.1853013830000005,-1462.758918238338 -1584,1584,T107K,-0.10607589,-0.8798790890000001,-1.856462104,-2.542279501,-2.826024012,0.081818737,-0.08632605300000001,-0.125825726,0.005627337,-0.8535523909999999,-0.9062057859999999,-1.81834459,-1.894579618,-2.620006972,-2.464552029,-2.791872956,-2.860175068,2.02188291,0.165689055,-11.29827376,-11.01718398,-13.43854657,-10.51215192,-10.65620234,-10.86728398,-7.673180941,-3.7253785,-1460.8256289875135 -1585,1585,T107M,-0.051601632,0.002363175,-0.034747812999999995,-0.124915125,-1.95630099,0.012062908,-0.048998270999999996,-0.054204992,-0.112471975,-0.083563788,0.088290138,-0.032598527,-0.036897097999999996,-0.080140588,-0.16968966100000002,-1.6108927769999999,-2.301709203,0.912097357,1.330147775,-8.216527464,-7.041995087,-10.02701324,-7.393778656,-6.424787277,-10.19506306,-6.212597858,-2.572752913,-1457.0102873202413 -1586,1586,T107L,-0.074287777,0.0062464719999999994,-0.043664057,-0.043679744000000006,-0.66359724,0.029544038999999998,-0.05293743099999999,-0.095638123,0.108238994,0.007016871,0.005476073000000001,-0.013739462,-0.07358865099999999,-0.038803311,-0.048556177,-0.455369717,-0.871824763,1.4639968819999998,1.857108215,-7.606464367999999,-6.389024582,-10.10613092,-6.134499817000001,-5.83137796,-9.571288559,-5.718375816,-0.767916582,-1451.2085832580924 -1587,1587,T107N,-0.209311849,-0.050723141,-0.071298341,-1.337212398,-2.7090025389999997,0.06979353599999999,-0.19302995,-0.22559374699999998,-0.049934304000000006,0.017208892,-0.118655174,-0.011404798,-0.131191883,-1.226366944,-1.448057851,-2.495142941,-2.9228621360000004,0.649874505,0.7219526190000001,-9.746452257,-10.96557829,-11.53718527,-9.931805458,-9.699254951,-6.5984373089999995,-7.882789742000001,-3.9237075960000003,-1465.7549994578585 -1588,1588,T107Q,-0.09114126,-0.645504764,-1.7177096,-2.224016025,-2.8087905319999997,0.045515108,-0.053032123,-0.129250396,-0.274612344,-0.578222977,-0.712786551,-1.546268334,-1.889150866,-1.9889087719999998,-2.4591232769999998,-2.762834748,-2.8547463160000004,3.0440825339999997,1.24977112,-11.11122651,-11.19680244,-11.948319699999999,-10.33884042,-9.571616608,-12.50055339,-7.3233043989999995,-2.593493499,-1463.5099361240864 -1589,1589,T107P,-0.082385536,-0.7429915709999999,-1.623525057,-2.071185571,-2.692235412,0.014034158,-0.080294165,-0.08447690599999999,0.047424915,-0.69042979,-0.7955533509999999,-1.6385004769999998,-1.6085496369999999,-2.051518449,-2.090852692,-2.4480260830000002,-2.93644474,3.6758891119999997,1.831969524,-10.66188441,-9.054914162000001,-11.11852548,-10.11252228,-11.26722214,-11.75623798,-7.425574601,-5.195922235,-1464.8013778124005 -1590,1590,T107S,-0.063023453,-0.002286058,-0.020659847,-0.037549822000000004,-0.120848921,0.006681967,-0.059511982000000005,-0.066534923,0.020251943999999997,-0.004162211,-0.000409905,0.005252621,-0.046572315,-0.056939616,-0.018160028,-0.06069739,-0.181000452,1.4947475909999999,2.571027563,-3.9436725630000002,-4.82815535,-3.7731485289999998,-3.93549456,-4.454940285,-2.7266240919999998,-3.861202154,-1.8308423319999998,-1462.0602612518705 -1591,1591,T107R,-0.096467989,-0.91830941,-1.739487519,-2.12219694,-3.115506105,0.070291051,-0.079894087,-0.11304189099999999,0.062058008,-0.8710744359999999,-0.965544383,-1.5830487690000001,-1.8959262680000002,-2.0215332480000003,-2.222860631,-3.369490491,-2.861521718,2.956030648,1.082917297,-10.35652335,-10.3496273,-8.388540932,-10.63298698,-9.757784332,-12.65367719,-7.152128635,-1.416514441,-1459.8231178242713 -1592,1592,T107W,-0.092796846,-0.20823349100000002,-2.018788625,-2.3155303959999998,-2.837835535,-0.056818785,-0.07478468099999999,-0.11080901,0.124150972,-0.170884898,-0.245582083,-1.9432833269999998,-2.094293922,-2.620006972,-2.0110538190000002,-2.791872956,-2.883798113,0.704593385,-0.107056604,-14.99517335,-14.28831615,-16.59741884,-13.52005363,-13.13989748,-17.43018063,-10.67972857,-9.388821529,-1460.746439148672 -1593,1593,T107V,-0.06609955299999999,0.055780315999999996,-0.020894247,-0.015299563,-0.579767453,0.040601554,-0.058921176,-0.073277929,-0.14086984,0.043549062,0.06801157,0.049542708,-0.09133120199999999,-0.012202251,-0.018396875,-0.35459478299999997,-0.804940123,1.213534075,1.7760240109999998,-6.503037901,-6.539518715,-8.185112671,-4.971032082,-4.6697944410000005,-8.149731597999999,-5.938536115,-2.713634532,-1449.7746477997862 -1594,1594,T107Y,-0.122312517,-0.17789928,-1.342013136,-1.883432763,-2.7886962989999997,0.033194758,-0.12209441300000001,-0.12253062,0.089173388,-0.03812146,-0.3176771,-1.134937291,-1.54908898,-1.869652883,-1.897212642,-2.5855869119999997,-2.991805685,2.579685884,1.19681407,-13.25593437,-13.33255616,-15.33804868,-11.69383807,-10.44134105,-15.47388791,-8.388545527,-4.420660361,-1458.8335890001617 -1595,1595,E108A,0.04423713,0.05940076,0.10152702400000001,0.064489462,0.055104957,0.007468575999999999,-0.017011613000000002,0.105485872,-0.223351347,0.074562435,0.044239084000000005,0.07769686599999999,0.12535718199999998,0.10360461300000001,0.025374311,0.04281331,0.067396603,1.056413169,2.781572971,-4.817972856,-5.24288578,-4.185154137,-5.720643462999999,-3.8765407260000004,-5.064640175,-4.751247602,-1.431641436,-1450.3723500566557 -1596,1596,E108C,0.054647535,0.070085315,0.046737695,0.059532193,-1.1093403259999999,0.028800658,0.014324638999999998,0.094970431,-0.025339585,0.087268521,0.052902109,0.077734074,0.015741316,0.133154422,-0.014090036,-1.073348756,-1.145331895,0.476470085,1.326397574,-9.947922702,-10.626047,-9.115237099,-12.03734997,-9.39135051,-8.569628929,-7.924446742000001,-5.26608638,-1449.4912137216888 -1597,1597,E108D,0.050245730999999995,0.07831624599999999,0.052930784,0.01712767,0.0069821990000000006,0.050361434000000004,0.042026169,0.058465293,-0.119420308,0.01310759,0.14352490199999998,-0.0028972390000000002,0.108758807,0.046746971,-0.012491631999999999,-0.025313459,0.039277856,1.148165013,2.480467834,-5.394160091,-6.159121452000001,-6.127450806000001,-4.525999634,-4.605263603,-5.552964958,-5.135150605,-1.269333176,-1455.399844264146 -1598,1598,E108G,0.029924597,0.050773349,0.016068095,0.046607315,0.010259220999999999,-0.011323511999999999,-0.0219643,0.081813494,-0.142452984,0.05974401,0.041802687000000005,0.042758412,-0.010622223,0.106598376,-0.013383746,-0.02113054,0.041648982,1.193938266,2.61408574,-4.171162999,-3.976314926,-3.64113588,-4.951774498,-3.597467308,-4.689122383,-3.3218777580000003,-1.152292359,-1452.5159328090958 -1599,1599,E108F,-0.038087241,0.051248234000000004,0.028130652000000003,0.019042923,-0.26269804199999996,0.016159505,-0.084279746,0.008105264000000001,-0.011020003,0.102229291,0.000267176,0.071279352,-0.015018048,0.072847951,-0.034762106,-0.1685956,-0.35680048299999995,1.321788369,2.165848299,-10.0088961,-10.22869862,-9.456073737999999,-12.22584662,-9.875491913,-8.258369591000001,-6.313327502999999,-3.4283240669999997,-1448.9700410990044 -1600,1600,E108I,0.062025548,0.062434922999999996,0.069933971,0.011138465,0.030259801,-0.027639242999999997,0.038953136,0.08509796,-0.184538487,0.034166685,0.09070316,0.10473664,0.035131301000000004,0.11542554199999999,-0.09314861199999999,-0.030945538999999998,0.091465141,1.543610422,3.106887046,-8.746913054,-8.267344162,-8.219911423,-10.51618153,-8.458154129,-8.272974022,-6.81128893,-3.6228542569999997,-1439.2884851708077 -1601,1601,E108H,0.090265595,0.068075236,0.048499138,0.032717391,-0.082148876,0.00019596900000000002,0.018549665,0.161981525,-0.148419832,0.081476417,0.054674055,0.043498450999999994,0.053499825,0.08656918,-0.021134398,-0.038076016000000004,-0.126221735,1.671448915,3.643209181,-9.058062598,-10.42551437,-8.489283936,-10.21726593,-9.273630562000001,-6.884618195,-6.096879405,-2.44755244,-1454.3318444732577 -1602,1602,E108K,-0.061698443,-0.03527386,0.076369076,-0.149806089,-0.05218598,-0.01648107,-0.16400082300000002,0.040603937,0.069635928,0.076918666,-0.147466386,0.18034532600000003,-0.027607175,-0.016236921,-0.283375257,-0.030691787999999998,-0.073680172,1.29941169,2.618994937,-2.106798457,-2.186979279,-1.4059729230000002,-2.9264690780000002,-2.754272484,-1.260298523,-2.115627396,-0.8956998840000001,-1446.557474006433 -1603,1603,E108M,0.08877214900000001,0.038777772,0.086781236,0.0077648330000000005,0.073928831,0.029826925,0.10870700300000001,0.068837295,-0.039508541,-0.0009912319999999999,0.078546776,0.08425293699999999,0.089309535,0.07262605400000001,-0.057096389000000004,-0.022489723,0.170347384,1.218791872,2.532598216,-8.469021992,-7.661807037000001,-7.236786781,-10.54538815,-8.935709282000001,-7.965418716,-6.805817773999999,-4.08540542,-1442.6266020750627 -1604,1604,E108L,0.008678048,0.025322802999999998,0.015932696,0.010233584,-0.11248789699999999,0.002339014,-0.033913545,0.051269641,-0.195181895,0.04161799,0.009027616,0.048832887,-0.016967495,0.090947196,-0.070480029,-0.07624761599999999,-0.14872817800000002,1.133834381,2.326636976,-8.591837092999999,-8.73566259,-7.366637756,-10.66653706,-9.313436377999999,-6.876911682,-6.267414425,-3.562636949,-1441.9559299368411 -1605,1605,E108N,0.0075842290000000005,0.012707598999999998,0.069950948,0.063434422,-0.012370212,-0.021528806,-0.060105682,0.075274139,-0.258832316,0.108064615,-0.082649417,0.107229619,0.032672276,0.132516613,-0.005647769,-0.004269147,-0.020471276,1.119145782,2.679590251,-7.43491279,-9.214789657999999,-7.1333882520000005,-8.098134254,-7.579346847999999,-5.148904938,-6.00527237,-2.414364831,-1447.2743595414795 -1606,1606,E108Q,-0.074604371,-0.020977037999999996,-0.013693516999999999,-0.023986554,-0.029396715,-0.001302233,-0.143456413,-0.0057523290000000005,-0.1588434,0.047028569000000006,-0.088982645,-0.00892674,-0.018460294,0.039877355,-0.087850463,-0.011764212,-0.047029218,1.671448915,3.643209181,-3.832586317,-3.873794868,-3.199175758,-4.513622826000001,-3.4008967360000004,-4.175441398999999,-4.455707267,-0.8861070059999999,-1451.542733043898 -1607,1607,E108P,0.025526204,0.043687102,0.072138572,0.038882905,-1.062669137,-0.017015042,0.004882365,0.046170042,-0.19732982699999999,0.054817354000000006,0.032556849,0.063647016,0.080630128,0.097471184,-0.019705375,-0.981395308,-1.143942966,0.36817852,1.3246697,-8.266399173,-8.056739136000001,-6.900642075,-9.11571946,-7.30249144,-9.956403755,-5.6551715410000005,-2.840339532,-1448.15519515099 -1608,1608,E108S,0.066924184,0.069532613,0.09196311199999999,0.040856756,0.054907278,-0.004265635,0.025985886,0.107862481,-0.173868352,0.09653791800000001,0.042527308,0.066484328,0.11744189599999999,0.100333164,-0.018619653,0.051277842000000004,0.058536713,1.192749345,2.8990608960000004,-3.7532092269999997,-4.338897964,-2.3932953340000003,-5.184978912,-3.884992271,-2.963881653,-3.199792064,-1.273824206,-1447.5687334928662 -1609,1609,E108R,0.052082248,0.044000145,0.043302612000000004,0.031351357999999996,-0.043445211,0.016199359,-0.013462402,0.11762689800000001,-0.127270399,0.060784877,0.027215412,0.060077782999999996,0.026527441000000002,0.078897439,-0.016194723,-0.015352352,-0.07153807,1.114053806,2.46394564,-4.9083773530000006,-6.642658577000001,-4.0830711289999995,-5.766293365,-4.092625381,-3.957238312,-3.6481892510000002,-1.4716025019999999,-1442.9566174219362 -1610,1610,E108T,0.015862006,0.040637482,0.04021724,0.010824258,-0.02672906,0.018528503,-0.023118125,0.054842137,-0.10266234199999999,0.07327328799999999,0.008001675,0.043322022,0.037112458,0.092922385,-0.07127387,-0.008909354,-0.044548766,1.306881923,2.817773842,-5.2886713180000005,-6.871187172000001,-5.026187279,-6.4336660000000006,-4.507327255,-3.604988884,-5.186376055,-2.190113563,-1440.105119580403 -1611,1611,E108W,-0.014283801,0.035825199999999995,0.019013858,0.055401382,-0.423567818,0.0347198,-0.0013858310000000001,-0.02718177,-0.43551405,0.079808194,-0.008157794,0.022076646000000002,0.015951069,0.12123530199999999,-0.010432539000000001,-0.389852841,-0.457282795,0.478564286,1.417825828,-10.55188933,-9.672628952,-9.927555717,-11.53928992,-10.20073944,-11.41923262,-6.383179094,-2.628107846,-1447.207507729996 -1612,1612,E108V,0.058347243,0.042376881,0.034249179,0.05983645,0.021242083999999998,-0.016108232,0.024756272000000003,0.091938214,-0.157816699,0.026484735,0.058269025999999995,0.041207892999999995,0.027290465,0.094391461,0.025281438,0.000470871,0.042013296,1.22191688,2.693886263,-8.081966182,-7.517504089,-7.391281372000001,-9.934244606,-7.481418242999999,-8.085382598999999,-6.827085286,-3.355521,-1439.8617021734826 -1613,1613,E108Y,0.017741002,-0.014282467,0.058323004000000005,-0.031823613,-0.185633878,0.013022338999999999,0.01348771,0.021994293999999998,-0.285078926,-0.016231198,-0.012333735,0.079489147,0.03715686,0.090449739,-0.154096965,-0.103935605,-0.267332151,1.264393939,2.307717902,-9.676736302,-9.710886009,-9.791089394,-11.91658926,-9.4297323,-7.535384552000001,-6.7790771560000005,-1.4241448190000001,-1446.813358281739 -1614,1614,K109A,0.02844406,0.046878381,0.03504426,0.029736288,0.017570764,0.043498195,0.048005702000000004,0.008882418000000001,0.036429266,-0.01956826,0.113325022,0.011890379,0.05819814,-0.031857893,0.091330469,-0.009999934,0.045141462,1.132987694,2.327309098,-4.353227469,-3.785223808,-4.974219399,-3.858998016,-6.278419029,-2.869277092,-4.4666974,-0.971510338,-1451.2251929622144 -1615,1615,K109C,-0.027875421,0.073119575,0.0016240470000000002,0.039279574,-0.977215953,0.059233019000000005,0.04944343599999999,-0.10519427699999999,0.192399601,0.024353376,0.121885773,0.041275955,-0.038027861,0.0040354,0.074523748,-0.623321397,-1.3311105090000002,0.8828937790000001,1.451681311,-9.029963824,-9.753609062,-9.405678879,-9.001555229,-9.783966545,-7.205009407,-7.470204852999999,-2.454464573,-1456.7265398451127 -1616,1616,K109E,-0.000292405,-0.001584097,0.013331059,-0.013742216000000002,-0.046458354,0.026554888999999998,0.042322642,-0.042907451,0.098374751,-0.040287743,0.037119549,-0.015904589,0.042566707,-0.069310542,0.04182611,-0.067520377,-0.02539633,1.340688798,2.4032097169999997,-3.7992583019999997,-2.601505898,-4.471028015,-4.480221123,-4.301773735,-3.1417627410000004,-4.332568487,-0.688184265,-1447.19675383484 -1617,1617,K109D,-0.014672826000000002,0.011774978,0.0027994359999999998,-0.016769497,-0.042958069,0.057486722000000004,0.043002433,-0.072348085,0.15804675599999998,-0.036312283,0.059862238,-0.01140437,0.017003242,-0.081347592,0.047808598,-0.09108136800000001,0.005165231,1.3626647980000002,2.259569601,-5.181684586,-3.136458916,-6.395323715,-5.259214447,-5.50312394,-5.61430191,-4.741204381,-1.555315251,-1443.8645098051056 -1618,1618,K109G,0.002672515,0.047687515,0.019483748999999998,0.0074065469999999994,-0.0064317540000000005,0.0232358,0.029711275,-0.024366246,0.200450605,-0.021930058,0.11730508699999999,0.033183047,0.00578445,-0.034426677999999995,0.049239772,-0.028513605,0.015650098,1.481553083,2.665887239,-6.023096526000001,-5.08488327,-7.091028641,-5.441892776,-6.82598082,-5.671697121,-5.566770764,-2.337747721,-1451.8025653124787 -1619,1619,K109F,0.024535317999999997,0.09553667199999999,0.079844958,0.073698489,-0.125324548,0.018485131999999998,0.04040084,0.008669795,-0.061269657000000005,0.014932932,0.176140412,0.045900542,0.113789374,-0.038426149,0.185823127,-0.160404393,-0.09024470300000001,1.324858101,2.14707842,-9.482551186,-11.86960992,-9.504344254,-9.07549144,-9.866027016,-7.097283295,-6.876971451,-1.5404844640000002,-1455.7774505000561 -1620,1620,K109I,-0.039742176000000004,-0.053011092,0.043483997999999996,-0.021389766,-0.063511355,0.020715605,-0.006954792,-0.07252956,-0.36848922700000003,-0.05407080000000001,-0.051951384,0.091192051,-0.0042240559999999995,-0.074264574,0.031485043,-0.082467058,-0.044555650999999995,1.4178042830000002,2.340412478,-8.714991187,-9.287385994,-7.74149324,-8.217804825,-8.864197014,-9.46407486,-7.24171599,-3.532216432,-1449.531608866062 -1621,1621,K109H,-0.078775275,0.009830945,0.01970605,-0.017491391999999998,-0.05099694,0.018876801999999998,-0.074524471,-0.083026079,0.018443486999999998,-0.010319856,0.029981745,0.032826065,0.006586034,-0.012552737,-0.022430047,-0.034888048,-0.06710583099999999,1.171423235,2.36905779,-4.7742416930000005,-5.712094467000001,-4.953259238999999,-4.6698836980000005,-5.596277359,-2.939693703,-6.139817371,-1.94328294,-1453.6451736097224 -1622,1622,K109M,-0.006816332,0.046203492,0.002561437,0.055370333,0.041160179,0.015175306000000001,0.038773977,-0.05240664,0.080310751,-0.020278637,0.112685621,-0.0009823260000000002,0.006105199,-0.032131464,0.14287213,0.010067186,0.07225317099999999,1.201458267,2.6370695669999997,-6.4391431720000005,-7.202456757,-6.757499825,-6.974284988,-6.128202278,-5.133272011,-7.01634083,-2.212230898,-1451.420454105828 -1623,1623,K109L,0.024717412,0.026432294,0.037757097999999996,0.046900884000000004,0.011094306000000002,0.015152957,0.061901702999999995,-0.01246688,0.059906795,0.0050914359999999995,0.047773152,0.038330667,0.037183528,0.002928705,0.090873063,-0.002426671,0.024615282999999998,1.158967774,2.5137537709999997,-5.065708559,-6.16477417,-6.2161759110000006,-4.464871567,-4.271160713,-4.211560432,-5.100827861,-1.3224483040000001,-1446.2799817346968 -1624,1624,K109N,-0.019115398999999998,0.043923962000000004,0.033537661,0.050502122999999996,0.031006255,0.003545671,-0.007555361,-0.030675437000000003,-0.020059794,0.026066452,0.061781471,0.08502998699999999,-0.017954666,0.018136731,0.082867514,0.060654988,0.0013575220000000001,1.2472596120000001,2.952494681,-3.295075883,-2.149512573,-3.837780579,-3.887907753,-3.3232231139999997,-3.2769553989999998,-4.851799407,-1.91274472,-1455.9832775262184 -1625,1625,K109Q,-0.011806025,0.023379151,0.060186079,0.061298219,0.015313737,0.045651698,0.035043181,-0.05865523,-0.073786214,0.046121525999999996,0.000636775,0.125620494,-0.005248336,0.005176029,0.117420409,0.031025984,-0.000398511,1.3495148209999999,2.8391011280000003,-1.7707762480000002,-1.491281937,-1.660228012,-2.173121521,-2.147014755,-1.3822350159999999,-2.535952549,-0.890693142,-1454.3158567748033 -1626,1626,K109P,-0.006093254,0.02762997,0.021596887000000002,0.004347282,-0.973440827,0.067834302,0.024208274,-0.036394782,0.15166666,-0.024876491,0.08013643,0.004595882,0.038597891,-0.046332934000000006,0.055027498,-0.714737675,-1.2321439779999999,0.780478639,1.4069428380000002,-5.760922615,-6.8338524629999995,-6.02622628,-3.940642632,-6.910540939,-5.093350761,-5.372931787000001,-1.8365425030000002,-1446.7889278931543 -1627,1627,K109S,-0.00356124,0.015488962,0.026857679,0.021227856,-0.01347513,0.007251985,0.032232027,-0.039354507000000004,0.12458144,-0.055158248,0.086136172,0.044291240999999995,0.009424116,-0.039920473,0.082376184,-0.028478978,0.0015287179999999999,1.25549214,2.396280602,-5.521957959,-5.40689595,-5.322072952,-5.509878998,-6.807999535,-4.56294236,-5.937251974,-1.6363116919999998,-1448.875589599833 -1628,1628,K109R,0.03040023,0.046499582000000005,0.034492993,0.030856777999999998,0.007215051,0.009392594,0.062332983,-0.0015325229999999998,0.121597005,-0.038441381000000004,0.131440544,0.023714845,0.04527114,-0.022369304,0.08408285900000001,-0.033042678,0.04747278,1.4118036330000001,2.5506220490000002,-3.1053936280000003,-3.7529663089999996,-2.538917099,-2.988654083,-3.9854639510000003,-2.2609666980000003,-3.743749663,-0.9750058140000001,-1448.5354610676877 -1629,1629,K109T,0.038970563,0.06631382200000001,0.05520607599999999,0.052106105,0.002104742,0.013535529,0.08414337,-0.006202245,0.229572444,-0.021937414,0.154565058,0.03030905,0.080103101,-0.002941022,0.10715323199999999,-0.019370109,0.023579592000000003,1.181000236,2.530186669,-3.641806458,-2.583330475,-4.192586929,-4.0333724669999995,-4.976899162,-2.422843254,-4.421138463,-1.577395446,-1453.8416485586204 -1630,1630,K109W,-0.010106988,0.052725192000000004,0.04005632,0.021347414,-0.11899215,0.028891632999999996,0.014321028000000001,-0.034535002999999995,0.142850326,0.006723125,0.09872725800000001,0.055397750999999995,0.024714887999999997,-0.028193256,0.070888084,-0.122814947,-0.115169353,1.2476712840000002,2.168986241,-9.504720107,-11.28918531,-10.07206214,-8.715817863,-9.138697769,-8.307837447999999,-7.087690927000001,-3.3641366039999996,-1457.1667275964282 -1631,1631,K109V,-0.001895956,0.009295376,-0.0042364759999999994,0.001333875,-0.035012295,0.020518336,0.03358644,-0.037378352000000004,0.020425816,-0.055035553,0.073626305,0.007891389,-0.01636434,-0.035711047999999995,0.038378797,-0.062937337,-0.007087253000000001,1.327578822,2.422303233,-7.798070059,-9.234369727999999,-7.187826645,-7.569894791,-8.599716835,-6.3985422970000005,-7.000823671,-2.7027640639999997,-1449.2368123144843 -1632,1632,K109Y,0.004076891,0.053019665,0.02609488,0.033641295,-0.101598564,0.011192236000000001,0.038526223,-0.030372442000000003,0.19266036,0.001490611,0.10454871800000001,0.018088259,0.034101501,-0.008622444,0.075905033,-0.067302713,-0.135894415,1.2199872859999998,2.328097342,-9.082824135,-11.67648757,-9.34545668,-8.764673683,-9.667875549,-5.95962719,-6.58106454,-1.8902279709999998,-1450.9432095712982 -1633,1633,H110A,0.038637755,0.077784625,0.034206373,0.030551256000000002,-0.180897312,0.047387519,0.011621886000000001,0.065653623,0.010695158,0.09208838300000001,0.063480866,0.052462227,0.015950518,0.067023073,-0.005920562,-0.143030748,-0.21876387600000002,1.319181323,2.2254431059999997,-5.844996631,-7.387093056,-6.263704712000001,-5.084287239,-4.557429405,-5.932468742,-5.835245925,-1.69919104,-1443.8487773165107 -1634,1634,H110C,0.031304961,0.000502866,0.0014431560000000001,0.002518984,-0.942352686,0.095586062,0.035427066,0.027182856000000002,-0.181501802,-0.062912505,0.063918237,-0.036075143,0.038961454,-0.092512871,0.097550838,-0.642132943,-1.242572428,1.428927681,1.707311847,-9.454433798,-11.098486300000001,-10.53846781,-8.20671666,-8.391663086,-9.036835136,-8.398658036,-5.707223483,-1454.9437054228038 -1635,1635,H110E,0.067938409,0.069692113,0.082693061,0.057591152,-1.050391483,0.099180611,0.09904100099999999,0.036835816,0.018173968999999998,0.00603821,0.133346015,-0.013630645,0.17901676600000002,-0.017055446000000002,0.13223774900000002,-0.9532632659999999,-1.1475197,0.868901074,1.3882805040000001,-8.832541965,-10.15199719,-11.00059943,-7.37324115,-7.174894814,-8.461977233999999,-6.625025449,-2.722010828,-1440.2259334828705 -1636,1636,H110D,0.073783953,0.13292474099999999,0.127604283,-0.469381462,-1.824052084,0.060888529000000004,0.056869777999999996,0.090698128,-0.345003933,0.044416445,0.221433037,0.067032475,0.18817609100000002,-0.27143342,-0.667329504,-1.8563532530000002,-1.791750915,1.32213546,1.350662228,-7.923399594,-8.729996796,-7.145591476,-7.283502876,-6.985531204,-9.472375618,-6.902109617000001,-2.851297565,-1443.2413152973168 -1637,1637,H110G,0.046511183,0.071084305,0.042653119,0.052788706,-0.224713885,0.11181844099999999,0.02718088,0.06584148599999999,-0.137006296,0.035292979,0.106875631,0.030255646,0.055050592,0.023714392999999997,0.08186301900000001,-0.203686384,-0.245741386,1.508372056,2.252694637,-8.531174968,-10.52473109,-8.708365738,-7.808646507000001,-6.832405388,-8.781726112000001,-6.802260489,-4.125594996,-1445.4067486482672 -1638,1638,H110F,0.005827308000000001,-0.014051913999999999,0.061629027999999995,0.003411133,-0.053775393,-0.027656737,0.025612084,-0.013957468999999998,-0.16891267399999998,0.11219097199999999,-0.140294799,0.052958847,0.070299209,0.020939256,-0.01411699,0.021442298,-0.128993083,1.139725805,2.466694997,-4.711570827,-6.490245811,-4.993813049,-4.356510452,-3.5856920469999998,-4.131592773,-5.222799118,-1.063678543,-1455.826664771419 -1639,1639,H110I,-0.18625944,-0.05413914400000001,-0.169448335,-0.391798994,-1.990195929,0.023401997,-0.198251957,-0.174266922,0.065170532,-0.043935765,-0.064342523,-0.09965131599999999,-0.239245353,-0.231138825,-0.552459162,-1.555323257,-2.4250686000000004,1.4447624609999998,1.4264729390000002,-9.154582873999999,-9.748728722000001,-9.221094566,-9.275327873,-8.635115891,-8.892647316,-7.132626362000001,-3.517522407,-1446.5436725942418 -1640,1640,H110K,0.15775979199999998,0.117709009,0.064340507,0.10697723699999999,0.012441677,-0.0025155729999999997,0.117059201,0.198460382,0.25705605800000003,0.041950765999999994,0.193467251,-0.01833594,0.147016954,-0.013672115,0.22762658800000002,-0.081207512,0.106090865,1.316692716,2.348542741,-6.15234933,-8.230588623,-5.487371819,-5.883220177,-5.427245926,-5.733320107000001,-6.072108159,-1.827919626,-1444.7032093890011 -1641,1641,H110M,-0.055114977,-0.012243677,0.005485667,-0.00033342,-0.156592771,0.085418282,-0.06679742799999999,-0.043432525,-0.110920727,-0.000301968,-0.024185385,-0.010924752,0.021896086000000002,-0.019750146,0.019083306,-0.1165173,-0.19666824100000002,1.23962028,2.164649125,-8.188103514,-8.968504379,-7.134278877000001,-9.57928717,-7.8454686129999995,-7.412978531,-6.188690228,-2.203635534,-1447.2908624592237 -1642,1642,H110L,0.048633537000000004,0.037931989,-0.002580328,0.030381736,-0.418581883,0.105899845,0.063006011,0.034261063,-0.079971591,0.025331112000000003,0.050532865999999996,-0.013807924,0.008647268,-0.018326977,0.07909044900000001,-0.333150528,-0.504013238,0.9977921340000001,1.6206715740000002,-7.004101031,-7.95456192,-6.263857123999999,-7.620977005,-6.1663538739999995,-7.014755234,-4.835962873,-0.792689715,-1443.8688185354695 -1643,1643,H110N,0.001891826,-0.015215195,-0.021520455,-0.005085763,-0.016681125,0.056325555,-0.043714407999999996,0.04749806,-0.19239377,-0.06441946700000001,0.033989077,-0.036860486,-0.006180423000000001,-0.069328729,0.059157203,-0.028601172999999997,-0.0047610759999999995,1.31205633,2.46737095,-4.1409125289999995,-4.916292992,-3.9408578189999997,-3.973261368,-4.265060349,-3.609090118,-4.3440403110000005,-1.43195963,-1454.7684402582236 -1644,1644,H110Q,0.021155674,0.059326207,-0.023658292999999997,-0.012208962,-0.231536315,0.063621163,0.04409549,-0.001784143,-0.11776015199999999,0.056877652,0.061774761,-0.031228214,-0.016088371,0.040261915,-0.064679839,-0.18359223300000002,-0.279480396,1.2285872359999999,2.001724344,-5.553862802,-6.647646324,-6.199977646000001,-4.978148323,-4.475428024,-5.468113692999999,-6.221746767999999,-2.213554205,-1447.6199259469286 -1645,1645,H110P,0.033783594,0.058611995,0.0068167,-1.489324481,-2.301066404,0.074725595,0.059368099,0.008199088,-0.115721575,0.032301478,0.08492251099999999,0.007755535,0.005877864,-1.318417957,-1.660231005,-2.184386165,-2.417746642,0.5102835579999999,0.70543257,-9.39150408,-10.94757689,-9.635793677999999,-8.409570442,-7.976939728,-9.987639664,-6.9953604060000005,-2.547429062,-1455.5087920958176 -1646,1646,H110S,0.149701731,0.131534928,0.103573376,0.064524863,-0.160450531,0.07679719,0.173644923,0.125758539,-0.130378543,0.063867348,0.199202508,0.040630655,0.166516097,0.010896076999999999,0.118153649,-0.191646452,-0.12925461,1.275083748,2.043950382,-7.442917828,-7.801526009,-8.396411842000001,-6.106453781,-6.56011412,-8.350083389,-6.678400827000001,-2.84462119,-1449.082165482454 -1647,1647,H110R,0.057305195,0.066930269,0.036511361,0.055122012000000005,-0.059301023,0.027311383999999998,0.054205927,0.060404463,-0.061007277,0.038711062000000004,0.095149475,0.034448441,0.038574281,0.019603164,0.09064086,-0.030992706000000002,-0.08760933900000001,1.2360777040000002,2.567918366,-3.375171178,-4.200438255,-3.469648842,-3.3369304810000004,-2.489448105,-3.379390205,-3.4065854110000005,-0.685438714,-1454.4254790451378 -1648,1648,H110T,0.100636716,0.11055311699999999,0.043779389,0.10421038099999999,-1.55125933,0.056698258,0.111180129,0.09009330199999999,-0.27592301399999997,0.060139475,0.16096675900000001,0.020488538,0.067070239,0.07757552599999999,0.130845236,-1.544327873,-1.558190786,0.60515725,1.313752295,-7.573074097999999,-8.246716034,-7.85227388,-7.697088394,-6.809079787999999,-7.260212395,-6.061448112000001,-3.30187053,-1451.5287670842372 -1649,1649,H110W,0.087682249,0.054165230999999994,0.010769338,0.048566727000000004,-0.560469723,0.11286315599999999,0.0827058,0.09265869800000001,-0.130283272,0.04293783,0.065392632,0.077789256,-0.056250580999999994,0.042308541,0.054824912999999996,-0.40491642299999997,-0.716023023,0.609118759,1.449400134,-8.208751024,-11.12367922,-10.12506767,-7.212851906,-5.426374099999999,-7.155782219,-5.23797326,-3.308831413,-1457.4861848452128 -1650,1650,H110V,0.058491357,0.08129044099999999,-0.00890535,0.018520619,-1.7412102319999998,0.100334431,0.095954469,0.021028243999999998,-0.047490512,0.016437306999999998,0.146143575,0.009018255,-0.026828955,0.010183534000000001,0.026857702999999997,-1.592465065,-1.8899553980000001,0.46002635399999997,1.305268325,-7.610896207000001,-7.759206841,-7.096888725,-8.411404305,-7.633542915,-7.153438248,-5.849242852000001,-2.359017037,-1446.1766687566414 -1651,1651,H110Y,0.114829691,0.177005297,0.175593952,0.045922594000000004,0.104755124,0.02413368,0.06548359599999999,0.164175785,0.052936075,0.066170598,0.287839995,0.12646296,0.22472494399999998,0.075071965,0.016773223,0.052340612,0.157169635,1.283942732,2.878264802,-3.3007122819999997,-2.744105621,-3.642023445,-3.458591728,-3.0268205339999996,-3.6320200810000003,-4.218799341,-1.0426746409999998,-1449.7362313619815 -1652,1652,L111A,-0.02653579,-0.035827894,-0.003869327,-0.057030278,-0.17892214899999997,-0.004677636,-0.018803564,-0.034268016,-0.046270399000000004,-0.03257593,-0.039079857,0.012577041,-0.020315694,-0.068047673,-0.046012883,-0.09770544099999999,-0.26013885600000003,1.49477802,2.415633588,-3.9082429339999996,-4.663923927,-2.7029652939999997,-3.877145226,-3.005191589,-5.291988632,-4.194999462,-0.51667604,-1445.620904468 -1653,1653,L111C,-0.04349062,-0.014662399,-0.026231848,-0.070146843,-0.230763117,0.077583182,-0.029097032999999998,-0.057884207,-0.070120467,-0.039203341,0.009878544,-0.0067242330000000005,-0.045739462,-0.04734986,-0.092943826,-0.149381126,-0.312145108,1.487458285,2.284829967,-9.048746159,-9.831974197000001,-8.909032219,-9.233837776,-8.664613762,-8.604272842,-8.943109677999999,-5.3404849489999995,-1450.7964081987739 -1654,1654,L111E,-0.095685793,-0.082071992,-0.05410163,-0.083557101,-1.001409632,0.005979231999999999,-0.121621496,-0.06975009,-0.112727408,0.0016258,-0.165769783,0.012544762,-0.120748021,-0.035115403999999996,-0.131998797,-0.7862436859999999,-1.216575578,0.866332785,1.4149141180000002,-6.939059985,-7.99704995,-7.194197472000001,-7.394805855,-6.224513908,-5.884732742000001,-6.668784054,-1.897208284,-1450.064489735756 -1655,1655,L111D,-0.059369451,-0.017220878999999998,-0.010196289,-0.007861108,-1.705468068,0.001457449,-0.078360172,-0.040378729,0.025089991000000002,-0.0019627860000000002,-0.032478972,0.031571559,-0.051964135999999994,0.043677494000000004,-0.05939971,-1.2211960370000001,-2.189740098,0.622015482,1.33147378,-8.097880161,-9.436693169,-9.480560822000001,-8.544797562000001,-6.805825386,-6.221523865,-6.328573276,-0.534537639,-1450.2410091045313 -1656,1656,L111G,-0.049181958,-0.039091834,-0.010697775,-0.035929492,-1.338578008,0.042470537999999995,-0.04655093,-0.051812985,-0.038032887,-0.005902086,-0.072281581,0.019700956000000002,-0.041096505,0.006800786999999999,-0.07865977,-1.264576194,-1.4125798219999999,0.70107297,1.33468519,-6.916784602000001,-8.239035568,-3.908784462,-8.019172096,-6.301642997999999,-8.115287888,-6.61099249,-1.778660712,-1447.138964840211 -1657,1657,L111F,-0.020655987,-0.017356114,-0.032008436,-0.07482338599999999,-0.056213048,0.056454534,0.013239182,-0.054551155,0.09012177800000001,-0.063274707,0.028562478999999998,0.010269241,-0.074286112,-0.108692015,-0.040954756,-0.09916966199999999,-0.013256433,1.5153777019999999,2.418097152,-5.009586122,-6.010768897999999,-5.300861305,-4.618344093,-5.0832345430000005,-4.034721771,-6.234747921,-2.135161391,-1447.7419483447447 -1658,1658,L111I,-0.02350057,0.033284014,-0.017627259,-0.000264236,0.051210423,0.008236486,-0.030142025,-0.016859115,-0.121272989,-0.046381926,0.112949953,0.027495439,-0.062749957,0.06545429,-0.065982762,0.018934282,0.083486563,1.142877423,2.7858118289999996,-2.310262315,-1.8449330290000001,-2.386923943,-2.913589623,-2.0323097,-2.373555283,-3.610687787,-0.765635732,-1452.2138116671704 -1659,1659,L111H,-0.064360297,-0.010672718999999999,-0.022777067999999998,-0.028970195,-0.11959502699999999,0.03374217,-0.078189968,-0.050530625999999995,-0.059712108,0.012010477,-0.033355914,0.053295178,-0.09884931300000001,0.020466022,-0.07840641200000001,-0.071874645,-0.167315409,1.2290995340000002,2.361328104,-7.615979767000001,-9.163797417,-7.909092682000001,-5.97138414,-7.402978325,-7.6326462710000005,-7.546785667000001,-1.78749682,-1444.1857271720655 -1660,1660,L111K,-0.027043373,-0.054481634,-0.052749002,-0.078842333,-0.445290177,0.029784212,-0.003139714,-0.050947031,0.007045488000000001,-0.112802616,0.003839348,-0.035494525,-0.070003478,-0.043189477000000004,-0.11449518800000001,-0.277948911,-0.6126314429999999,1.4406248590000001,2.005843982,-6.370346673999999,-7.557965462,-4.472382095,-6.801442451000001,-5.609434555,-7.410508804,-6.078971082000001,-1.179979916,-1446.2826829482801 -1661,1661,L111M,-0.043207511,-0.064593793,-0.058739247,-0.11902195199999999,-0.008178508000000001,0.0073366130000000005,-0.008060951,-0.07835407,-0.169045771,-0.028430092,-0.100757493,0.013794641000000002,-0.131273135,-0.002540273,-0.23550363100000002,-0.035353794,0.018996779,1.267886367,2.607370612,-5.240131137,-5.354148499,-5.195412964,-5.347448067,-5.066250999,-5.237395157,-6.87807075,-3.4480986760000003,-1454.510162315797 -1662,1662,L111N,-0.13494976,0.001111975,-0.025067205,-0.029740506,-1.7939235080000002,-0.019385915,-0.156808964,-0.113090555,-0.010683278999999999,0.025540748,-0.023316799,0.044884775,-0.095019185,0.07620347599999999,-0.135684487,-1.56045107,-2.027395945,0.59848298,1.3126232740000001,-8.124309364,-9.73889315,-7.028220009,-8.740358978,-7.504422256000001,-7.6096524279999995,-7.664919737000001,-2.371944116,-1446.403065793682 -1663,1663,L111Q,-0.094078926,-0.029606527999999997,-0.0006122559999999999,-0.06544736599999999,-0.08332181,0.059973926,-0.087131956,-0.101025895,-0.128129025,-0.007006691999999999,-0.052206364000000005,0.051911042000000004,-0.053135552999999995,-0.014538768,-0.116355963,-0.10981490099999999,-0.056828718,1.3093393999999998,2.222427284,-5.303983983,-6.573063682999999,-4.757867134,-4.516465759,-4.7808577880000005,-5.89166555,-5.67076556,-2.105276155,-1448.9806663985364 -1664,1664,L111P,-0.057375521,-0.0065282809999999995,-0.021040383,-0.033667302999999996,-1.124830808,0.063305069,-0.05090578,-0.063845261,-0.040539913999999996,-0.008809485,-0.004247076,0.020385643000000002,-0.062466409,-0.025640925,-0.04169368,-0.8737038359999999,-1.3759577790000002,0.708401941,1.37035961,-6.5658568189999995,-7.48830378,-6.641046417,-6.400317337000001,-5.336764175,-6.962852386000001,-5.629951077,0.211347068,-1452.568217040971 -1665,1665,L111S,-0.053143752999999995,-0.018670079,-0.05027729400000001,-0.042522476,-0.25549611699999997,0.023508763999999998,-0.063845992,-0.04244151400000001,0.014224073,-0.02266183,-0.014678328000000001,-0.017428465,-0.083126123,-0.014656799,-0.070388153,-0.22988010899999997,-0.281112125,1.45657963,2.113026454,-6.028996951,-7.864766106,-5.408120255,-6.1846288760000006,-5.436980957,-5.250488563999999,-6.322337131,-0.936089205,-1443.706745007541 -1666,1666,L111R,-0.063575711,-0.036546873,-0.007371007,-0.053460170999999994,-0.788257468,0.054496551,-0.074563499,-0.052587922,0.017769353,-0.005450356999999999,-0.067643389,0.005813658,-0.020555672,0.002620139,-0.10954048,-0.576171564,-1.0003433720000001,0.632759499,1.4063301419999998,-5.66368194,-6.512621895,-4.499097954,-4.408205269,-5.616918724,-7.281565857,-6.012748567,-1.3889517619999998,-1443.8196385838091 -1667,1667,L111T,-0.01541583,-0.044761405,-0.04337692,-0.03898053,-0.055475814000000005,0.008589567,-0.01452311,-0.016308549,0.011815091000000002,-0.073700385,-0.015822423999999998,-0.046904819,-0.03984902,-0.048655585,-0.029305475,-0.086277376,-0.024674251,1.3526152059999998,2.29140379,-4.0918962919999995,-4.984808578,-3.4108252869999998,-5.029428543,-3.253249275,-3.7811697769999997,-5.008665478999999,-1.050372661,-1449.9662953251973 -1668,1668,L111W,-0.0023387910000000002,-0.011565061000000001,-0.027921996,-0.04624976,-0.08093974,0.022875655,0.012230033000000001,-0.016907615,-0.059375203,-0.03076246,0.007632338000000001,0.0051328829999999995,-0.060976875,-0.043837929000000005,-0.048661591,-0.11147849300000001,-0.050400987,1.5345992169999998,2.41063141,-8.943880603,-9.99213443,-9.816200333,-8.691106972,-8.473055977000001,-7.746905303999999,-8.227982867,-3.7191765689999996,-1446.865042108111 -1669,1669,L111V,-0.00018323599999999998,-0.010792247,0.0070174519999999995,-0.010388135,0.03501739,-0.056564712,-0.03321218,0.032845709,-0.094185899,-0.030473835,0.008889341,-0.008275879,0.022310782999999997,-0.010045941999999999,-0.010730328,0.0018364429999999999,0.068198336,1.1861853999999998,2.528187983,-1.552259564,-1.181892738,-1.418170746,-2.101700302,-0.95222596,-2.107308075,-2.460434255,0.702979705,-1458.6024166578427 -1670,1670,L111Y,-0.059021773,-0.016906024,-0.004627352,-0.034095154,-0.079256332,0.011085748000000001,-0.063045356,-0.05499819,-0.17529472,-0.010781251,-0.023030797000000002,0.03847238,-0.047727083,0.032985232,-0.10117554,-0.022514778,-0.135997885,1.140691649,2.405539867,-8.267697539,-9.277981911,-9.192569191,-8.001496536,-7.56608017,-7.300359886,-7.74286341,-3.109384185,-1446.4094328596257 -1671,1671,T112A,0.011455861999999999,0.042646225,0.004205864,0.036363413,0.040527258,0.045147429,0.016444668,0.006467055,0.058735864000000006,0.06313674,0.02215571,0.021308083,-0.012896355,0.032891312,0.039835514,0.037868888999999996,0.043185627000000004,1.085105223,2.64713552,1.405103749,1.576309456,1.367824799,1.6767867509999999,0.867921646,1.5366760940000002,-0.960019016,1.894238911,-1462.2183381658979 -1672,1672,T112C,-0.079643134,0.031055802999999996,-0.044951537,-0.020494342,-0.224731163,0.080471446,-0.104899887,-0.054386381,0.089680668,0.049570069,0.012541536,0.010023436,-0.09992651,-0.007395281,-0.033593403,-0.22836411399999998,-0.221098212,1.493993453,2.143045545,-4.592858835,-4.582690986999999,-5.3120612110000005,-3.9851454160000004,-5.907271515,-3.1771250460000005,-6.69245672,-2.1463341330000003,-1457.5672791874968 -1673,1673,T112E,0.02122863,0.074811056,0.072928275,0.082174505,0.028461722000000002,0.092016477,0.010184095,0.032273164,0.070287533,0.105308731,0.04431338,0.079731738,0.066124812,0.076083414,0.088265595,0.017743635,0.039179807999999997,1.144345991,2.8086535560000003,-0.9533887409999999,-0.6607883529999999,-1.725560165,0.362041061,-2.475657509,-0.26697873699999997,-3.981641353,1.271451842,-1462.3332132338546 -1674,1674,T112D,-0.038839234,0.018815949,-0.034780396,-0.000195934,0.001599065,0.03837516,-0.032881226,-0.044797240999999995,-0.120618955,0.037716698,-8.48e-05,-0.021246805,-0.048313985999999996,0.0063731790000000005,-0.006765047,-0.0049474440000000005,0.008145574000000001,1.543610422,3.106887046,-0.498414029,-0.8029488220000001,-1.1673283840000002,0.809302933,-0.186737663,-1.1443582079999999,-2.772053685,2.1451237340000002,-1465.9430814809166 -1675,1675,T112G,0.026610681,0.056156316,0.05185028,0.042714632,0.068757914,0.029777355,0.012004666,0.041216696000000004,0.00193298,0.051880354000000004,0.060432278,0.08867423199999999,0.015026326999999999,0.036638906,0.048790357,0.027814554,0.109701273,1.203076918,2.833734906,-0.499880321,-1.3888083269999998,-0.622971489,1.310886536,-1.5368383330000002,-0.261669991,-3.49745091,2.762128844,-1460.6458922047168 -1676,1676,T112F,0.041803513,0.04781826,0.027126255,0.027919667000000002,0.049081384000000006,-0.08405665400000001,-0.001915726,0.085522751,0.067282023,0.039853959,0.05578256,0.01785667,0.036395839,0.027365321,0.028474012000000003,-0.022342141,0.12050490800000001,1.301408296,2.6159409030000003,-6.73074155,-5.78285994,-7.770326294,-6.019188065,-9.100101624,-4.981231827,-6.360780882999999,-2.2176044569999998,-1453.5130277448334 -1677,1677,T112I,0.019470795,0.08200268299999999,0.042175594000000004,0.029017987999999998,0.084895434,0.037864818,0.054533882,-0.015592293,-0.12886903,0.107009108,0.056996257,0.072620428,0.01173076,0.050497642,0.007538334,0.061297064000000005,0.108493804,1.16819842,2.9379045169999998,-4.418763606000001,-4.290004082,-4.642508095,-3.401336723,-5.748713157999999,-4.011255974,-6.574473338,-2.1850472930000002,-1458.4200262101367 -1678,1678,T112H,-0.054934325,-0.011697365,0.005451869,0.039837585,0.012700158999999999,0.076252052,-0.050813362,-0.059055287000000005,-0.120820577,0.029746814,-0.053141544000000006,0.042293217,-0.031389479,0.053359641,0.026315527999999998,0.023295827999999998,0.0021044889999999998,1.142036181,2.7338256210000003,-4.191354694,-4.578929237,-5.161709877,-2.610330185,-5.435196312,-3.170607857,-5.05105806,-0.17606046,-1460.9843022958376 -1679,1679,T112K,0.041602994,0.028859506,0.057573624000000004,0.07160876599999999,0.061175424000000006,0.057879865999999995,0.039882917999999996,0.04332307,-0.00885153,0.050966434000000005,0.006752578,0.053555052,0.061592195999999995,0.046076873,0.097140658,0.052379238,0.06997161,1.130137451,2.8466913889999996,-1.203565997,-1.1176535490000001,-2.1255835419999998,0.057271721,-2.341949005,-0.48991561100000003,-3.032705327,0.323976954,-1461.992306612432 -1680,1680,T112M,0.035176819,0.040108987,0.068080856,0.066504614,0.008222842,0.020392238,0.026224226,0.04412941099999999,0.223313488,0.048346213,0.03187176,0.012953793,0.12320791800000001,0.035132327000000005,0.09787689999999999,0.006412079,0.010033605,1.189559922,2.647125377,-5.120463095,-5.235074265,-5.831234932,-4.251454605,-6.573985167999999,-3.710566505,-6.914458118,-2.699482966,-1454.7550120498054 -1681,1681,T112L,-0.020201141000000002,0.014839311,0.025108456,0.051326414,0.012445887,0.026128879,0.0030726290000000003,-0.043474911,0.11486556099999999,0.037082585,-0.007403964,0.05513705,-0.0049201390000000005,0.037678939,0.064973888,0.011421126,0.013470646999999999,1.085105223,2.64713552,-5.219605275,-4.919007835,-5.966357062999999,-3.7938082580000003,-6.94035154,-4.478501678,-6.231496266000001,-1.995860259,-1448.9799524317496 -1682,1682,T112N,-0.009063640999999999,0.04443331,0.041230197999999996,0.06422636799999999,0.049527478,0.044450194000000005,0.00014086,-0.018268141,-0.16363113599999998,0.057433773,0.031432847,0.037887996,0.044572399000000006,0.048151461,0.080301275,-0.023630287000000003,0.12268524300000001,1.111723942,2.5148718580000002,-1.343508752,-1.7315645290000001,-1.848088219,-0.824544594,-1.3734450759999999,-0.939901344,-3.486347711,0.987854975,-1465.511445440352 -1683,1683,T112Q,-0.029575915,-0.04801441099999999,-0.076122429,0.005136482,-0.051817832,0.038793821,-0.021353836,-0.037797994,-0.04262593,-0.045223096,-0.050805725,-0.024569542000000003,-0.127675315,-0.014183298,0.024456262000000003,-0.045104423,-0.05853124,1.183851575,2.389461889,-2.8750772660000004,-2.742340439,-3.5551237789999997,-1.441348289,-5.0015898210000005,-1.6349840009999999,-4.2877325619999995,0.064901418,-1457.0434208200313 -1684,1684,T112P,0.010092697,0.02156935,0.02324934,0.038241332999999995,-0.018968098,0.025197176,0.018488552,0.0016968410000000001,0.037723779,0.067618586,-0.024479886,0.049680034000000005,-0.0031813540000000004,0.030507377999999998,0.045975287000000004,0.004426022,-0.042362217,1.671448915,3.643209181,-2.300674808,-2.103926163,-1.792808975,-1.673031273,-5.184353722,-0.749253906,-3.729280301,1.476461483,-1453.3866173303686 -1685,1685,T112S,0.01785622,0.012895163999999999,0.004823326,0.022131401000000002,0.018286818,0.021466087000000002,0.025060455,0.010651984,0.020512163,0.005982124,0.019808203,-0.003847701,0.013494353,0.005371847,0.038890955,-0.010130763000000001,0.046704398,1.237023233,2.517427644,-0.600694351,-0.41161332700000003,-0.199223183,-0.36838012700000006,-2.090945038,0.066689919,-3.474092637,0.567603443,-1462.6529482048936 -1686,1686,T112R,0.008951165,0.019459038999999997,0.029985337999999997,0.007776676,0.019411118,0.041464363,0.019223758,-0.001321428,0.050982377999999995,0.008553233,0.030364845,0.016862861,0.043107814,0.0016668129999999998,0.013886539,-0.027450181,0.066272416,1.1842911329999999,2.48731783,-2.920324733,-3.239659004,-3.224276955,-1.605931664,-4.358470886,-2.173285156,-4.192094414,0.000245234,-1455.6219852948561 -1687,1687,T112W,-0.010893508,0.09226162800000001,0.063152755,0.072421922,0.006492854,0.020733544,-0.04275198,0.020964964,0.10157989099999999,0.147517274,0.037005981,0.085212865,0.041092644,0.10825706199999999,0.036586782000000005,0.02663463,-0.013648923,1.1102709990000001,2.803064708,-6.791883339,-6.659152572999999,-7.382258705,-5.6984283520000005,-8.972465775,-5.24711129,-7.24112777,-3.239852511,-1451.7261559679173 -1688,1688,T112V,0.034623584,0.036818457,0.043372126,0.050460389,0.000436853,0.031395998,0.027551501000000003,0.041695666,0.05420835,0.071188232,0.002448681,0.078886421,0.007857831,0.035200922,0.065719856,-0.012663352,0.013537057,1.09141726,2.505512625,-1.9384017169999999,-1.936430649,-1.718351135,-1.6613186569999998,-2.904645248,-1.471262894,-4.61998564,-0.49938643200000005,-1459.5997518463992 -1689,1689,T112Y,-0.042348475,0.01752965,0.027047939,0.008257396,0.054425557,0.035622799,-0.081096972,-0.0035999770000000003,-0.0248642,0.059336235999999994,-0.024276936000000002,0.101613613,-0.047517736,0.064787049,-0.048272257,0.07249087,0.036360243,1.087675146,2.722527363,-6.2895237260000005,-5.672615829,-8.590038094,-5.148101097,-8.00239341,-4.0344702,-5.997148011,-1.39790749,-1455.3789608366787 -1690,1690,D113A,-0.015131512,-0.095492424,-0.061248224000000004,-0.062972207,-0.06605382,-0.001297056,-0.026328939,-0.003934084,-0.421350768,-0.052407105,-0.138577742,-0.11328061800000001,-0.009215829,-0.032594212000000004,-0.093350202,-0.08546155400000001,-0.046646085,1.369038687,2.358196104,-4.2948486830000006,-4.809648605,-3.426271416,-4.006963928,-4.047490753,-5.183868713,-4.894475094,-0.06534175099999999,-1454.3039798056707 -1691,1691,D113C,0.079122188,-0.053242532,-0.005413694,-0.044918278,-0.304002288,0.049325737,0.049676465,0.10856791,-0.39391251899999996,-0.070931171,-0.035553892000000004,-0.022601589,0.011774202,0.000105953,-0.089942509,-0.252564429,-0.35544014700000004,1.45712359,2.077991044,-9.300791753,-10.08878091,-8.12403804,-9.510665367,-9.865063843,-8.915410599,-8.93442439,-4.811168197,-1455.1001304523088 -1692,1692,D113E,0.07024436,-0.033817562,-0.004989163,0.072579605,-0.005727654,0.025004009,0.139482681,0.0010060380000000001,-0.33321467899999996,-0.012064511000000002,-0.055570612,-0.075085944,0.065107619,0.053311881,0.091847328,-0.016031727,0.004576419,0.92629403,2.330417922,-1.364215793,-1.309781219,-1.366298882,-1.7381445469999999,-1.390731384,-1.016122932,-4.054731454,-0.247443031,-1461.581513732206 -1693,1693,D113G,-0.00845206,-0.131759496,-0.024608395,-0.016542548,-0.060906319,0.007929273,-0.031408464,0.014504345,-0.17236338699999998,-0.09359898400000001,-0.169920008,-0.10820284,0.058986051,-0.006475514,-0.026609581,-0.07821117400000001,-0.043601463,1.5413732580000001,2.49883553,-3.552532123,-3.214412148,-3.081349655,-3.4376115339999997,-5.496100082000001,-2.533187195,-5.7621087,1.177608532,-1448.5300943758339 -1694,1694,D113F,0.013360006,-0.054449080999999996,-0.011758665,-0.002033386,-0.231182605,0.057668167,0.0014014029999999999,0.025318609,-0.283996656,-0.049593115,-0.059305047,-0.068288553,0.044771223,0.00157129,-0.005638061999999999,-0.267187637,-0.195177572,1.587489219,2.15923086,-9.803046328999999,-10.62046109,-7.563960442000001,-10.21429469,-11.85833366,-8.758181763,-8.790789574,-4.549415499,-1448.3653641375713 -1695,1695,D113I,0.018361401,-0.055953496,0.003130716,0.021720153,-0.10136269199999999,0.035900992,0.018729766999999998,0.017993033999999998,-0.24778448399999997,-0.021077092999999998,-0.090829898,-0.066688149,0.07294958,0.026251833999999998,0.017188472,-0.128638001,-0.07408738200000001,1.386680422,2.2677355,-7.996512762,-9.105486588,-7.262091255,-7.759926865,-9.577324562000001,-6.277734542999999,-7.19297863,-2.1392693990000002,-1453.2623312561773 -1696,1696,D113H,0.053154368,-0.097064427,-0.042392569000000005,-0.04771351099999999,-0.034760101,-0.027257313,0.013883598,0.09242513699999999,-0.252181428,-0.118028075,-0.076100778,-0.11321584400000001,0.028430706,-0.04515751,-0.050269510999999996,-0.085004955,0.015484753,1.36102041,2.314229171,-6.383333542000001,-7.31452832,-4.285401787,-6.772558311,-6.881367477,-6.662811812999999,-6.716489619,-1.8506309269999999,-1453.307798704598 -1697,1697,D113K,-0.023584661,-0.040841142999999996,-0.031843672,0.011931752,-0.042644241,0.015565672,-0.015373181999999999,-0.03179614,-0.019595556,-0.0036212970000000003,-0.078060988,-0.048979246,-0.014708097,0.031454282,-0.007590778,-0.033583311,-0.051705170999999994,1.3330098540000002,2.637029907,-3.780527765,-4.191460281,-3.8623471830000002,-4.40760453,-4.224083595,-2.217143234,-3.9857646860000004,-0.200880578,-1447.1165996259078 -1698,1698,D113M,0.021792613,-0.121371565,-0.036394794,-0.03859152,-0.11808895400000001,-0.022514115,0.043920485999999995,-0.000335261,-0.012879528000000001,-0.09646205599999999,-0.146281073,-0.102279872,0.029490284,-0.065611123,-0.011571917,-0.201049046,-0.035128861000000004,1.432427684,2.111935461,-8.529227145,-9.488900635,-7.537936844,-8.632344887,-10.36845863,-6.618494728,-8.063207869,-3.587826783,-1450.4561697193421 -1699,1699,D113L,0.001230983,-0.082658381,-0.04663140599999999,-0.023582636,-0.187793488,0.041656433,-0.003536653,0.005998619,-0.305185955,-0.058608405,-0.10670835599999999,-0.105004095,0.011741284,0.025109294,-0.072274565,-0.212746322,-0.162840654,1.204637967,1.966333505,-7.675806174,-8.944348793,-6.529307387999999,-7.8540263370000005,-9.80164724,-5.249701111,-7.382634317000001,-1.929697468,-1446.9364476152696 -1700,1700,D113N,-0.003289525,-0.10198763599999999,-0.08778081300000001,-0.021207765,-0.052588139000000006,0.023045961,-0.017137178,0.010558128,-0.33321467899999996,-0.0445324,-0.15944287199999999,-0.12264250199999999,-0.052919123,0.016727427,-0.059142957,-0.058298314000000004,-0.046877962999999995,1.310227454,2.37781668,-3.901777501,-4.109251228,-2.600105591,-3.7807996060000004,-5.20781601,-3.81091507,-4.942077351,-0.9343369140000001,-1455.5620695324615 -1701,1701,D113Q,-0.006251139,-0.082461597,-0.043712282000000005,-0.026026505,-0.011883728999999999,0.002028102,-0.046422335,0.033920057,-0.36185986,-0.06012322,-0.104799973,-0.091252154,0.003827591,-0.014747831000000001,-0.037305178,-0.04847831,0.024710852999999998,1.427294333,2.456213609,-4.271402892,-4.889651871,-2.603302948,-4.962453979,-5.307768578,-3.593837082,-4.501103549,-0.56071467,-1456.833353513386 -1702,1702,D113P,0.019705121000000003,-0.051368187,-0.034524265,-0.030892901,-0.731114151,0.047504792000000004,-0.006139037,0.045549279000000005,-0.313745767,-0.046834407,-0.055901967000000004,-0.09445363400000001,0.025405105,-0.005969815,-0.055815987000000004,-0.644509979,-0.817718323,0.8352955559999999,1.442378991,-3.516033904,-3.202469048,-2.8431221239999998,-4.857700599999999,-3.3954136810000004,-3.2814640660000003,-4.508889684,-0.6217835939999999,-1450.0938362064771 -1703,1703,D113S,0.011476431,-0.061166171,-0.043993410999999996,-0.021342664,-0.023461345,-0.007596613,0.008574701,0.01437816,-0.245600265,-0.019292353,-0.103039989,-0.091465263,0.003478442,0.014786461,-0.057471789,-0.032472556,-0.014450133,1.262234571,2.455472153,-4.087348668,-5.014725502,-3.093674866,-4.142994453,-3.297485245,-4.887863274,-5.172966389,-0.12313697800000001,-1455.0999003844336 -1704,1704,D113R,-0.002822522,-0.11708718300000001,-0.06491939099999999,-0.049748510999999995,-0.084542119,0.007624429,-0.040613292999999995,0.03496825,-0.28310488100000003,-0.052610377,-0.18156398899999998,-0.110848504,-0.018990277,-0.017622124,-0.081874897,-0.08746409699999999,-0.081620141,1.36733654,2.341892996,-5.511529041,-6.578319327999999,-3.334143402,-6.357819222000001,-6.250551086000001,-5.036812164,-5.879213936,-0.49368908799999994,-1442.7879116940312 -1705,1705,D113T,0.037015457,-0.037334526,-0.015502806000000001,-0.00968365,0.022648909,0.000256886,0.009401691,0.064629222,-0.272393442,-0.023957035,-0.050712017000000005,-0.069014374,0.038008762,0.009798003000000001,-0.029165302,-0.008542009,0.05383982599999999,1.2700313540000001,2.57458469,-3.6450846689999996,-3.959183289,-3.7504104689999997,-4.157081734,-3.0630694660000004,-3.295678391,-3.7098041989999997,0.642943959,-1461.1946398438886 -1706,1706,D113W,0.023645436000000002,-0.10093603300000001,-0.06457817,-0.046143992,-0.320755549,0.062341886,-0.013554651000000001,0.060845522,-0.208275942,-0.073428917,-0.128443149,-0.126736601,-0.002419738,-0.069918535,-0.022369447999999997,-0.328800126,-0.312710972,1.536014856,2.037876761,-9.657498454,-10.60896717,-6.868633202000001,-10.16631997,-11.59500535,-9.048566582000001,-8.826552328,-4.828149529,-1447.4874000540003 -1707,1707,D113V,-0.041728481,-0.133429698,-0.030321518,-0.08259573,-0.086303752,0.087188424,-0.062374043,-0.021082919,-0.7011914640000001,-0.096349271,-0.17051012399999999,-0.075398084,0.014755049,-0.016954192,-0.148237267,-0.19391603,0.021308526,1.576861764,2.272458472,-7.041252718,-7.596784927000001,-6.49940107,-7.158358871,-8.094346763999999,-5.857371956000001,-6.436067333,-0.416098024,-1455.9106081807986 -1708,1708,D113Y,-0.00024946,-0.077922253,0.015943823,0.015987678999999998,-0.103097588,0.010656644,-0.022457045,0.021958125,-0.362178375,-0.002009696,-0.15383480900000002,-0.024881884,0.056769529000000006,0.072073572,-0.040098215,-0.08404550400000001,-0.122149671,1.173055706,2.275185432,-9.596172444,-10.75324971,-7.775384155,-9.815136833,-11.01723132,-8.619860199,-8.349510638,-4.268056883,-1449.3763578343205 -1709,1709,G114A,-0.052258945999999994,0.017891372,-0.056769734,-0.167600109,-1.768156619,-0.043331769000000006,-0.052199485,-0.052318406,0.018356638999999998,-0.014443755,0.050226498,-0.022364987000000003,-0.09117448,-0.029074517,-0.30612570100000003,-1.770387729,-1.7659255090000001,0.705964267,1.309951274,-3.5990383269999997,-3.189959175,-2.807847427,-3.8692616039999996,-4.346995987,-3.781127441,-5.396161454,-1.677790505,-1457.7315732943825 -1710,1710,G114C,-0.01753952,-0.012402567,-0.040880867,-1.1962679920000001,-1.693246199,-0.009382937,-0.007320245,-0.027758795,0.047249574,-0.071299301,0.046494167,0.014926887,-0.09668862,-0.917624222,-1.474911761,-1.9485477269999998,-1.43794467,2.215907864,1.586400324,-9.824396623,-9.722391685,-8.862535187,-10.44423263,-11.15914683,-8.933676788,-9.920189241000001,-6.480357687000001,-1463.9395920955576 -1711,1711,G114E,-0.081181612,-0.078714079,-0.10992716400000001,-1.51613864,-2.497687707,-0.036786754,-0.036290341000000004,-0.126072882,0.098856889,-0.062191986,-0.095236171,-0.085214153,-0.134640174,-1.4090941380000002,-1.6231831419999998,-2.101663324,-2.8937120889999997,0.81416984,0.720916986,-4.581427092,-3.2144325869999997,-4.154622986000001,-5.698572716,-5.564590851,-4.274916321,-6.04106102,-1.3588487480000002,-1456.2704161331058 -1712,1712,G114D,-0.017586551000000002,-0.012473668,0.067514041,-0.9091403440000001,-1.988670582,-0.059566247999999995,-0.034223662,-0.000949439,0.05349485599999999,-0.037151542,0.012204206,0.052720882000000004,0.0823072,-0.836929585,-0.981351103,-1.9822874469999998,-1.995053716,2.03843816,1.4866191380000002,-6.461937589,-5.942688277999999,-4.596543701,-9.465972359,-6.397940032999999,-5.906543571,-4.948080191,-1.998619221,-1458.0850046654232 -1713,1713,G114F,-0.010803281999999999,-0.0013015589999999999,0.042601344000000006,-0.21276210199999998,-1.7025912230000002,-0.022620475,0.001423519,-0.023030083,0.07810758799999999,-0.066307588,0.063704471,0.019168739,0.06603394900000001,-0.051352128,-0.374172075,-1.479285674,-1.925896772,0.71528473,1.323577597,-10.51306375,-8.568481827000001,-10.28085043,-11.22390545,-12.79444001,-9.697641022,-8.245593846,-4.852211453,-1458.450136421714 -1714,1714,G114I,0.029938626,-0.003227213,-0.884318388,-2.0159821780000002,-2.694101807,-0.066959387,0.05657081,0.003306442,-0.119240834,-0.035717282999999996,0.029262857000000003,-0.745701877,-1.022934899,-1.64153018,-2.390434175,-2.5723385309999998,-2.8158650819999997,2.305264804,1.158789879,-8.525697266,-9.164081001,-8.069800964,-8.872663719,-9.044659287,-7.477281357000001,-8.444392314,-3.175788416,-1451.3827445115894 -1715,1715,G114H,-0.062959066,-0.010459794,-0.016035178,-0.113281159,-1.947167109,-0.019273881,-0.024229606,-0.101688526,-0.11201479199999999,-0.010647865,-0.010271721999999999,-0.0068510409999999996,-0.025219315,-0.001212889,-0.225349429,-1.735283212,-2.159051006,0.750001987,1.311879328,-7.9079853270000005,-8.842045929,-8.006818932,-8.539644455,-7.992439667,-6.158977654,-7.143346854,-3.157490128,-1457.4167264164425 -1716,1716,G114K,-0.0027364940000000003,-0.01086061,-0.050661106,-0.523086564,-1.4954849540000001,0.027439099999999998,-0.010034594,0.004561606,-0.121603276,-0.07831109900000001,0.05658988,-0.067371113,-0.033951099,-0.418326376,-0.6278467520000001,-2.048104732,-0.942865175,1.586200202,1.3555022719999998,-5.790717247000001,-4.818640686,-5.259508583,-7.473128418,-6.6610644070000005,-4.741244141,-6.673126292,-1.832793388,-1453.1687140599824 -1717,1717,G114M,0.084114106,0.00922786,0.052482184,-1.128752379,-2.691067714,-0.055143399999999995,0.137125335,0.031102877,-0.063919886,-0.065867797,0.084323516,0.015414575,0.08954979199999999,-0.9141623109999999,-1.3433424459999999,-2.710272088,-2.671863339,0.7489601309999999,0.764557625,-9.253168694,-9.247984215,-8.733091805,-9.696616745,-10.34618143,-8.241969276,-8.345065635,-4.536344134,-1457.2435861467384 -1718,1718,G114L,-0.050435,-0.062348978,-0.029288896000000002,-1.528448965,-2.1345131040000003,-0.011980735,-0.015110489,-0.085759511,-0.045746262999999995,-0.06267444,-0.062023515999999994,-0.017565782,-0.041012009,-1.24095101,-1.8159469190000002,-2.411652614,-1.857373594,0.912563893,0.749804708,-8.105803751,-7.334414902000001,-7.2620929489999995,-8.832146729,-9.777332535,-7.323031639,-7.795384577999999,-2.282779556,-1451.179328984581 -1719,1719,G114N,-0.057363309,0.032821027999999995,0.000379228,-0.12269792,-1.9791036180000001,-0.011775207,-0.059416271,-0.055310345999999996,-0.015561775,0.033706608,0.031935447,0.017237217,-0.016478762,0.000132755,-0.245528594,-1.865174048,-2.093033188,0.6700260170000001,1.302175855,-7.059820638,-7.249414291,-6.0157404329999995,-9.91010611,-6.652781822000001,-5.471060532,-6.587049112000001,-1.966976726,-1458.3960018986836 -1720,1720,G114Q,-0.045663144,0.0018496779999999998,-0.004160515,-1.274182827,-2.111681837,-0.025283927,-0.03021725,-0.061109038,-0.080086842,-0.004895248,0.008594604,0.007220096,-0.015541125,-1.134590635,-1.4137750180000002,-2.354194526,-1.8691691480000001,0.7737229170000001,0.74414627,-4.872438417,-4.122978462,-4.391773872,-5.883182365,-5.946572395,-4.01768499,-5.373599185,-2.167280382,-1455.3371033971198 -1721,1721,G114P,-0.046022219,0.004069263,0.001909876,-1.3924653269999998,-2.048173868,-0.032586097,-0.043314727000000004,-0.04872971,-0.081993107,-0.010364735,0.01850326,0.003494888,0.000324863,-1.1267285009999999,-1.6582021519999999,-2.251298384,-1.845049351,0.8045882790000001,0.7461577159999999,-6.513716069,-8.119616501,-4.904628983,-7.882971931,-7.314987122000001,-4.3463758089999995,-6.4227165170000005,-2.266757889,-1448.6338380966336 -1722,1722,G114S,0.020665426,0.010883869,0.009627581999999999,-0.062394297,-1.6983153000000002,-0.039958661,0.029923098999999998,0.011407753,-0.020543218000000002,-0.055081258,0.076848995,-0.019789645,0.039044809,-0.045237844000000006,-0.079550749,-1.733286452,-1.6633441469999999,0.8505544559999999,1.316947228,-5.314125014,-5.613813545,-4.482084282,-5.569885017000001,-5.866602806,-5.038239418,-5.312657173,-1.6121347430000001,-1457.4364320677705 -1723,1723,G114R,-0.019843435,-0.006754785,-0.111614522,-1.544478784,-2.508646797,-0.033358566,0.005624947,-0.045311816,-0.12875509400000001,-0.011019128999999999,-0.00249044,-0.09722925199999999,-0.125999791,-1.3260567559999998,-1.762900811,-2.351840621,-2.6654529719999998,1.008379288,0.7548773809999999,-5.330821971000001,-3.8295086589999996,-6.295630104,-6.086318596,-5.552007248,-4.890645248,-6.531094649,-1.75195871,-1452.5888295779005 -1724,1724,G114T,0.008407985,-0.023327467999999997,0.016535778,-1.2128749909999998,-1.887151206,-0.032864213999999996,-0.016962848,0.033778817,-0.0017341820000000001,-0.061125349,0.014470413,0.012470193999999999,0.020601361999999998,-0.962133661,-1.46361632,-2.084827539,-1.689474872,2.133368712,1.4762068130000001,-5.66976028,-5.413350845,-5.298682503,-5.9479913479999995,-6.348618652000001,-5.340158051,-6.099292824,-0.9458575859999999,-1452.5085008759052 -1725,1725,G114W,-0.049827294,-0.029305054,-0.019590765,-1.155348911,-1.979103619,-0.029014825,-0.087860786,-0.011793801999999999,-0.194742737,0.02102922,-0.079639328,-0.047566711,0.008385182,-0.8314212540000001,-1.4792765669999999,-1.849379781,-2.1088274559999998,2.252496589,1.6488633940000001,-10.825883099999999,-10.22910381,-9.719610458,-11.99006111,-12.54962327,-9.641016853,-9.526568028,-6.212724442000001,-1460.815026823897 -1726,1726,G114V,-0.033008155,-0.019527878000000002,-0.205982146,-1.471611362,-2.478018652,0.0038431409999999996,0.020184786,-0.08620109599999999,0.010862417,-0.043885529000000006,0.004829773,-0.185896998,-0.226067293,-1.468541909,-1.474680815,-2.73141449,-2.2246228130000003,1.21290972,0.7688574990000001,-6.695513715,-7.410922089,-6.246939262000001,-7.145272713,-6.629886696,-6.044547812999999,-6.984001283,-2.2000305,-1451.4726496352814 -1727,1727,G114Y,-0.044944248,0.027786257999999998,-0.027859482999999997,-0.243021703,-1.924038428,-0.00392352,-0.029596638999999998,-0.060291856,-0.030569203,0.027105498,0.028467017999999997,-0.006352711,-0.049366255,-0.062284167,-0.423759239,-2.015920049,-1.832156806,0.812527606,1.298921062,-9.847987239,-8.644797394,-10.15470536,-10.35064492,-11.81950072,-8.270287804,-7.785549904,-3.34927669,-1460.2055524978787 -1728,1728,M115A,-0.056622202,-0.068531384,-0.041467528,-0.014917788000000001,-1.660348986,0.004916551,-0.08350287599999999,-0.029741528,0.000584594,-0.036433507000000004,-0.100629261,-0.05160791,-0.031327145,0.03360058,-0.063436156,-1.496845816,-1.823852155,0.528379095,1.312400113,-7.657069527999999,-6.2566417539999994,-9.884267883,-9.415676285,-6.702970992999999,-6.025790726,-5.331669625,-2.545473917,-1453.7336684539914 -1729,1729,M115C,0.032658348,-0.147687105,-0.028378116000000002,-0.039747957,-2.29634603,0.08279916400000001,-0.072921218,0.13823791400000002,-0.07788031299999999,-0.11578217800000001,-0.179592031,-0.002883751,-0.05387248,-0.025741882,-0.053754030999999994,-1.702029922,-2.890662137,0.845256399,1.320221315,-11.94820169,-10.82647069,-13.7040987,-13.11784296,-12.2934129,-9.799183205,-7.311900375,-4.765233907,-1453.4880497017875 -1730,1730,M115E,-0.077968902,-0.046352078,-0.18108629699999998,-1.448695008,-2.747736235,0.019163441,-0.141224768,-0.014713035,0.265702033,0.000687946,-0.09339210099999999,-0.040308689,-0.321863904,-1.227640216,-1.6697498,-2.510606212,-2.9848662569999997,0.752470486,0.730520507,-11.95940157,-10.22333407,-13.17702732,-13.41546438,-11.32630573,-11.65487634,-7.936900214,-5.622652144,-1454.4967605699785 -1731,1731,M115D,-0.038787071,-0.261846393,-1.326951676,-1.884608316,-2.42317742,-0.019872511000000002,-0.040484376,-0.037089765,0.060155795,-0.12666251,-0.397030275,-1.181590038,-1.4723133130000001,-1.794115463,-1.975101169,-2.158197204,-2.688157635,3.984665446,2.552604872,-15.14024923,-13.73035003,-16.68439781,-15.98276353,-15.43734532,-13.86638946,-9.962997698999999,-9.406221481000001,-1451.6337557760999 -1732,1732,M115G,-0.006099182,-0.062980091,-0.38756376600000003,-1.4406256080000002,-3.110310358,0.039335313999999996,-0.09790577,0.085707406,-0.076015051,-0.045485791,-0.08047439099999999,-0.258669831,-0.5164577,-1.389641237,-1.491609978,-2.7855053510000003,-3.435115365,1.4141554490000001,0.829538387,-13.76476277,-12.63482731,-14.82893662,-15.19069814,-13.48751903,-12.68183276,-9.174082662,-7.131535802,-1444.168748755008 -1733,1733,M115F,-0.163045833,-0.040782916,-0.074139547,-1.506492191,-2.231619507,-0.032316376,-0.144913936,-0.18117772899999998,0.0190297,0.024832119,-0.10639795099999999,-0.02900914,-0.11926995300000001,-1.390926572,-1.62205781,-2.031214725,-2.432024288,2.6859881519999997,1.783490196,-7.682103101,-4.912254471000001,-10.81711462,-5.300588295,-9.395210251,-7.985347862,-4.142649948,-1.6633750219999999,-1447.9566231155768 -1734,1734,M115I,-0.008825115,-0.017988973999999998,-0.033020477,0.013823225,-0.6841602940000001,-0.027353372999999997,-0.007512107,-0.010138123,0.104334031,-0.031112834,-0.004865114,-0.06977523599999999,0.0037342829999999997,-0.053054419000000005,0.080700868,-0.44144627799999997,-0.92687431,1.357250895,1.793329789,-4.6838435469999995,-3.39446933,-6.379566269,-4.6164899219999995,-4.610214729,-4.4184774860000005,-3.618939953,-1.341572605,-1450.3375171385705 -1735,1735,M115H,-0.121289784,-0.13370729,-0.17739117399999998,-1.510988192,-2.694574602,0.012189846,-0.131769805,-0.11080976199999999,0.034709904,-0.09946688,-0.1679477,-0.167157203,-0.187625144,-1.4247772509999999,-1.5971991330000002,-2.265980248,-3.123168955,0.743968995,0.7186011459999999,-12.74549892,-12.85342976,-15.10646534,-13.59494257,-11.84877366,-10.32388329,-7.183928192000001,-4.630262733,-1458.9058638243005 -1736,1736,M115K,-0.137168453,-0.07578979799999999,-0.077706493,-1.90351206,-1.942081163,0.040139334,-0.082431539,-0.191905367,0.14076329699999998,-0.063544973,-0.08803462199999999,-0.054065453,-0.101347533,-1.302218217,-2.5048059019999998,-1.967329954,-1.9168323719999998,2.815642752,1.931521494,-11.82922132,-11.58241544,-12.67465241,-13.0703722,-11.3271446,-10.49152195,-7.685133571000001,-5.080711508,-1450.396070255898 -1737,1737,M115L,-0.124186365,-0.098778892,-0.045003608,-0.040834802999999996,-0.112630744,0.001252237,-0.119539652,-0.128833077,0.050102232999999996,-0.068261582,-0.129296201,-0.075643276,-0.014363939,-0.035239433,-0.046430173,-0.083377853,-0.141883635,1.363850935,2.355303888,-3.897132072,-2.424484856,-4.911321648,-3.2678543010000003,-5.733329231,-3.1486703260000004,-3.94103758,-0.43244120700000005,-1453.0930137103423 -1738,1738,M115N,-0.042723175999999995,-0.041464127,-0.045461202,-1.565522461,-2.30546101,0.039907677,-0.055279293,-0.030167057999999997,0.146515626,-0.046895215,-0.036033038999999996,-0.060710157,-0.030212246,-1.51353474,-1.617510182,-2.405294109,-2.205627911,0.8031298920000001,0.7110049279999999,-14.702565099999997,-14.01788326,-15.68131265,-15.77742808,-14.01445329,-14.02174821,-9.962997698999999,-9.406221483,-1454.961236115545 -1739,1739,M115Q,-0.16367383,-0.084851946,-0.008220067,-0.052392805,-1.057211717,0.054061539000000006,-0.185895163,-0.14145249599999998,0.06405667,-0.016418943999999998,-0.153284947,0.013923461000000002,-0.030363595,-0.028140959,-0.076644651,-0.7656969579999999,-1.348726476,0.834080863,1.4121297030000002,-9.32518147,-8.043374817,-11.15993693,-10.32548768,-8.300877731,-8.796230194,-6.2145198079999995,-4.794254427,-1456.2575536514632 -1740,1740,M115P,-0.07672465099999999,-0.156759658,-1.372273813,-1.943167901,-2.825104778,0.016328867,-0.068898961,-0.08455034,0.03004814,-0.11103984800000001,-0.202479467,-1.413232825,-1.3313148000000001,-1.848113163,-2.038222638,-2.500990443,-3.149219113,4.1214818,2.548249186,-10.77149086,-10.00011649,-12.61098505,-12.03655227,-10.74829528,-8.461505203,-6.08220368,-3.41587074,-1457.149969285354 -1741,1741,M115S,-0.029678192000000003,-0.07116084,-0.03462944,-0.713154795,-2.116785912,0.03058248,-0.086401727,0.027045343,0.01516303,-0.040015366000000004,-0.10230631300000001,-0.082809325,0.013550446,-0.346626666,-1.079682923,-1.838772443,-2.39479938,1.52920832,1.387411341,-11.30751804,-10.53424852,-12.3439129,-12.62952574,-10.67317348,-10.35672956,-7.185035872,-4.660588547,-1447.573267061729 -1742,1742,M115R,-0.138576712,-0.08626314800000001,-0.064304828,-0.378250543,-1.9672593319999998,0.020707342,-0.154541892,-0.122611531,-0.000198898,-0.049448268,-0.12307802699999999,-0.054584279000000006,-0.07402537599999999,-0.19536805899999998,-0.561133027,-1.7516593059999999,-2.182859357,1.246257237,1.35406467,-9.835787199,-9.539482368,-12.11038084,-11.22650954,-8.888504303,-7.414058945,-6.487128912999999,-3.452822007,-1449.0631263209507 -1743,1743,M115T,-0.106577522,-0.055964106,-0.016948808,-1.198464385,-1.986188766,0.032687247999999995,-0.110913919,-0.102241124,0.047646272999999996,-0.038899405,-0.073028807,-0.041890821,0.007993205,-0.873435705,-1.523493065,-2.00343424,-1.968943291,2.182368381,1.5501801769999999,-9.322909662,-9.246922295,-9.679179863,-11.04959677,-8.203036575,-8.435812805,-6.546711579,-2.5108215019999998,-1451.5596602451988 -1744,1744,M115W,-0.17456010600000002,-0.27625793,-1.3987629830000001,-2.184385601,-2.906943098,0.025950839,-0.19703152899999998,-0.152088683,0.11309187,-0.124517879,-0.427997981,-1.3527256890000001,-1.444800277,-1.8983043240000002,-2.4704668780000003,-3.1074841060000002,-2.7064020889999996,2.5503311280000003,1.055091931,-12.7827295,-11.65941707,-15.46047152,-12.52841714,-14.11321976,-10.15212202,-7.098840595,-4.05813142,-1453.0938331480138 -1745,1745,M115V,-0.13470765099999998,-0.058465645,-0.08982387900000001,-0.039572447999999996,-1.68219455,0.06425125799999999,-0.12646585300000002,-0.142949448,0.0190297,-0.024681178999999998,-0.09225011,-0.09606245,-0.083585307,-0.021666373,-0.057478522000000004,-1.589698152,-1.7746909469999999,0.811550422,1.325087332,-6.050000311,-5.089568938999999,-6.7020296020000005,-5.394023697000001,-7.138596581,-5.925782738,-4.4929994330000005,-1.520890789,-1453.1795482649468 -1746,1746,M115Y,-0.08959731800000001,-0.035835628,0.006440156999999999,-1.5867161509999999,-2.522258013,0.017847125,-0.099426233,-0.079768403,-0.027502625,-0.050612729,-0.021058527,-0.01453207,0.027412383,-1.263133253,-1.9102990480000002,-2.4211605119999997,-2.623355514,0.785261256,0.7315211540000001,-11.77371922,-10.10593707,-15.19355828,-10.76927687,-12.00707725,-10.79274661,-5.849446893,-1.6157449380000002,-1441.1549743274227 -1747,1747,T116A,0.09639473900000001,-0.012390102,-0.042528551,-0.001876493,-1.3788882340000002,0.032008052,0.065276668,0.12751281,-0.151413632,0.078066843,-0.102847047,-0.057643337999999995,-0.027413762999999997,0.051185565,-0.05493855,-1.044282614,-1.7134938530000001,0.780854477,1.3606479740000001,-4.614339275,-4.161985672,-4.6212267460000005,-4.153857567,-5.838130637999999,-4.29649575,-5.179335489,-2.372269727,-1462.107580730226 -1748,1748,T116C,-0.08644798199999999,0.020035095,-0.029195316000000002,-0.025121597000000002,-1.5696690219999998,0.09548311699999999,-0.107448004,-0.065447959,-0.08100631,0.10409242699999999,-0.064022237,-0.000669527,-0.057721105,0.097499048,-0.147742242,-1.455091295,-1.684246748,0.533904654,1.31616875,-7.801314934,-7.0215245589999995,-7.528456032,-7.55381443,-9.330720345,-7.572059303,-8.612227385,-6.810902485,-1458.5498952195048 -1749,1749,T116E,0.069504655,0.066137848,0.027460795,0.020299755,-0.001675007,0.023687633,0.02916211,0.10984719999999999,0.0013449820000000002,0.08523705699999999,0.04703863900000001,0.030376475,0.024545114,0.010780007,0.029819502999999997,0.009128111,-0.012478125,1.671448915,3.643209181,-6.229341185,-5.011655403,-5.123377747,-6.718684509,-7.8361045229999995,-6.456883743,-6.452198833,-4.01517444,-1464.8786134948023 -1750,1750,T116D,-0.030855103999999998,-0.029356322999999997,0.022589177000000002,-0.016174991,-0.7672614109999999,0.085524086,-0.001411025,-0.060299182,-0.007220096,0.032587367,-0.09130001300000001,0.01243301,0.032745342999999996,-0.032087354,-0.00026262700000000003,-0.569440999,-0.965081822,0.7955026959999999,1.4483339780000002,-5.397210226,-4.51030629,-3.894584938,-6.098363991,-5.675298401,-6.8074975129999995,-6.857411849,-3.441201631,-1462.6955961734056 -1751,1751,T116G,-0.037451251,0.003788104,-0.025471307999999998,-1.057255801,-1.92948211,0.067372468,0.007750278,-0.08265278,-0.142067122,0.04611395,-0.038537743,-0.017096333000000002,-0.033846282000000005,-0.798570221,-1.31594138,-2.207586762,-1.651377457,1.883066057,1.36353168,-7.436768065,-6.649058983,-6.841107506,-7.244508652,-8.544755043,-7.9044101410000005,-7.329533248,-5.764104996,-1455.8060771096498 -1752,1752,T116F,-0.024081097000000003,-0.01206305,0.008642252,-1.341195415,-2.045538289,0.065804654,-0.021759234,-0.026402959,-0.089961153,0.038742007,-0.062868107,-0.022084492,0.039368995,-0.650529216,-2.0318616130000002,-1.85135772,-2.2397188569999997,1.9071971230000002,1.487728217,-9.036252297999999,-7.6808108289999995,-8.275699295,-8.774218239,-11.28936111,-9.16117202,-8.766760603,-7.1646290839999995,-1456.8832386811264 -1753,1753,T116I,-0.029547712,-0.036664545,-0.06452384900000001,-0.068939464,-1.5478838990000001,0.077119354,-0.011940481999999999,-0.047154941,-0.029644942,-0.002965925,-0.070363164,-0.063844135,-0.065203562,0.028888379,-0.166767306,-1.535769004,-1.559998793,0.62964893,1.3154106190000001,-7.1599022670000005,-6.423829994,-7.775798553,-6.781250664,-8.418593834,-6.4000382920000005,-7.352200868,-5.955867112999999,-1456.7823476470076 -1754,1754,T116H,0.02698576,-0.01569922,0.029027382,-1.036932022,-2.348609979,0.011537435,0.040118252,0.013853266999999999,-0.026944657,-0.000513047,-0.030885392,0.026332495,0.031722269,-0.664338379,-1.409525665,-2.380867044,-2.316352914,1.6694086419999998,1.274405174,-8.265350033999999,-7.846726135,-7.334351784,-8.873594246,-8.771982643,-8.50009536,-9.770391327,-9.847493683,-1466.5678589744493 -1755,1755,T116K,-0.026848944,-0.03467044,-0.029296087999999998,0.011737576999999999,-1.586312554,0.08553243199999999,-0.021459618,-0.03223827,0.10192437300000001,0.052448811,-0.12178969,-0.01356123,-0.045030945,0.073327867,-0.049852714000000006,-1.451992006,-1.720633101,0.5722939539999999,1.3157837209999999,-4.458234241,-3.6812696380000003,-3.9949545289999997,-4.943261818,-5.849586577999999,-3.82209864,-5.626272579,-3.5536470110000002,-1460.1270732921548 -1756,1756,T116M,0.026839618,0.001257632,-0.00284641,0.008295448,-1.060159582,0.075087842,0.015370074,0.038309162,0.09793389,0.029434847000000004,-0.026919584,0.0013549279999999998,-0.007047748,0.015276936000000001,0.001313959,-0.8225803490000001,-1.297738815,0.6806257840000001,1.371287564,-7.733835994,-6.800856727999999,-7.749093094,-7.481633636000001,-9.084618591,-7.552977921,-8.106534065,-6.655915322999999,-1453.747078507673 -1757,1757,T116L,0.020980627,0.015232158999999999,0.009699731999999999,0.008278787,-0.8311066909999999,0.066479028,0.032834317,0.009126937,-0.006812116,0.047584838,-0.017120521,0.014663819,0.004735645,0.022185026,-0.005627452,-0.658472336,-1.003741046,1.097736136,1.538400506,-6.853724618999999,-5.844785706000001,-6.786302765,-6.986213089,-8.223928528,-6.427393005,-7.641911601,-5.552171552999999,-1455.4564257455058 -1758,1758,T116N,-0.047183178,0.021534895,0.014729906000000001,0.039494819,-0.5730477279999999,0.090701393,-0.050073584000000004,-0.044292770999999995,0.001700524,0.083574623,-0.040504833,0.014603877,0.014855934,0.09619652599999999,-0.017206889,-0.390212785,-0.75588267,0.48237641299999995,1.4122088480000001,-4.0038519169999995,-3.77908374,-2.76343399,-5.301901199,-4.235599068,-3.939241585,-4.7429655330000005,-3.9558742789999997,-1461.9790387223475 -1759,1759,T116Q,0.085722727,-0.005381476,-0.001254338,0.01740643,-0.500701472,0.040098109,0.076431412,0.09501404199999999,0.010702508999999999,0.016964311,-0.027727262000000003,-0.027338078,0.024829402999999996,-0.003220111,0.03803297,-0.33382594,-0.667577003,1.3392136890000002,1.879034207,-5.649044252,-4.954283035,-5.140034462,-6.070448761000001,-6.811470032000001,-5.26898497,-6.587596811,-4.5443570189999996,-1463.9447233560495 -1760,1760,T116P,-0.046010731,-0.037404854,0.007097428,0.010524426000000002,-1.6762142930000001,0.034947385,-0.05518299,-0.036838472000000004,0.058135102,0.026031923999999998,-0.10084163199999999,0.024999426,-0.010804571,0.085652293,-0.064603441,-1.5106497369999998,-1.8417788480000001,0.46205937700000005,1.309133238,-4.195094287,-3.3560112610000004,-4.115027458,-4.071187141,-6.431942627000001,-3.001302948,-5.99379716,-1.898445868,-1460.8488083058037 -1761,1761,T116S,0.016682238999999998,-0.007373946,-0.031960188,-0.02026366,-0.073522367,-0.025618872,0.014746663,0.018617814,0.030712057,0.019879999,-0.03462789,-0.028017977000000003,-0.035902397999999995,-0.004516592,-0.036010727,-0.009275676,-0.137769058,1.171406769,2.578300048,-0.9724638729999999,-0.8109547420000001,-0.307503822,-1.231742119,-1.902097954,-0.610020729,-2.6544689619999997,-0.47846233899999996,-1461.8178349244408 -1762,1762,T116R,0.006765715,-0.012477792,-0.055089574,-0.02870607,-2.094839733,0.05584066099999999,0.021516828999999998,-0.0079854,-0.056438119,0.019530131000000003,-0.044485714,-0.05862743,-0.051551717000000004,0.018878483,-0.076290622,-1.7783367819999998,-2.411342683,0.622077378,1.304595661,-3.6911196210000004,-3.88523246,-3.1528385389999998,-4.065354773999999,-3.4462431560000004,-3.9059291760000003,-4.744740371000001,-3.333135843,-1460.975482292939 -1763,1763,T116W,0.00755318,-0.008474647,-0.956158623,-1.884637119,-2.491227844,0.044729514000000005,0.01371971,0.001386649,-0.028409395,0.026117757000000002,-0.04306705,-0.864858268,-1.047458977,-1.706536059,-2.062738179,-2.092071505,-2.890384182,3.521989718,2.239853713,-9.128722887999999,-7.850205513,-8.478898636,-8.918624649,-10.97518143,-9.420704216,-9.521499716000001,-8.649720343,-1463.6313506923616 -1764,1764,T116V,-0.003884605,0.016952352,-0.004320679,0.021454367000000002,-1.5398455869999998,0.061938764,-0.009394143,0.001624934,-0.131484986,0.066963829,-0.033059126,-0.00981907,0.001177713,0.047698082999999995,-0.00478935,-1.5023209519999998,-1.5773702219999999,0.13344225,1.300237148,-8.139961909,-7.088425179,-8.937940758,-7.674339752000001,-9.430620529,-7.56848333,-8.819686118,-7.223782664,-1459.3367578252219 -1765,1765,T116Y,-0.060882052,-0.039298247,-0.01677034,-0.728765137,-2.162579891,0.112041439,-0.027246054,-0.094518049,-0.06344302,0.025227443999999998,-0.10382393699999999,-0.0067199830000000006,-0.026820696,-0.300444298,-1.157085975,-2.250251174,-2.0749086080000003,1.319165487,1.294205984,-8.985182095,-7.471534233,-8.631373306,-8.698054375,-11.08645425,-9.038494307999999,-9.05453873,-7.473254964,-1460.8783365525305 -1766,1766,V117A,-0.250511096,-0.025107282,0.019636518000000002,-1.213244232,-1.9474422409999999,0.024692884,-0.007830031999999999,-0.49319216,-0.022486147999999997,0.045369985999999994,-0.095584549,0.015459293999999998,0.023813741,-0.8125354020000001,-1.6139530619999998,-1.9790380930000002,-1.9158463890000001,2.007254243,1.478538322,-6.256039713,-5.98053302,-4.507085593999999,-7.746361702000001,-8.587839942999999,-4.458378304,-5.207618673,-1.8478204480000002,-1457.1762465909123 -1767,1767,V117C,-0.226375298,-0.006504276999999999,0.032854397,-1.201150381,-2.283712065,0.08412371199999999,-0.012151081000000001,-0.440599515,-0.18045606399999997,0.000650069,-0.013658621999999999,0.053712199,0.011996595,-1.035231867,-1.367068895,-1.7631647209999999,-2.8042594089999997,2.804048289,2.085719938,-10.95268839,-10.00516948,-8.347687782000001,-14.83530769,-12.09111189,-9.484165131000001,-8.381039762999999,-6.306644863,-1451.9429453089833 -1768,1768,V117E,-0.276191234,-0.007437206,-0.525781157,-1.620442323,-2.565433678,-0.038608921000000004,0.0025622170000000003,-0.554944684,-0.015794267,-0.002937629,-0.011936782,-0.196379794,-0.8551825190000001,-1.384373259,-1.8565113869999998,-2.179588135,-2.95127922,2.433421696,1.5198229769999998,-11.76438717,-11.25055074,-8.804499214,-14.84908593,-13.84348036,-10.07431959,-9.511233958,-9.330018295,-1447.9825294371694 -1769,1769,V117D,-0.30705446399999997,-0.9162908340000001,-1.64686067,-2.214708265,-2.88154837,-0.041883015,-0.025988182000000002,-0.588120746,0.036429266,-0.934588237,-0.89799343,-1.7743309219999999,-1.5193904169999999,-1.9209317019999999,-2.5084848280000003,-2.8588140810000002,-2.904282658,3.371710382,1.384173742,-12.07038595,-11.42261776,-8.848602248999999,-15.74962344,-13.75812628,-10.57296002,-9.511233958,-9.330018295,-1442.4598733759485 -1770,1770,V117G,-0.259487311,-0.033888666,-1.108468384,-2.0105135290000002,-2.630401382,0.039384244,-0.061763724000000006,-0.457210897,-0.0038950440000000003,-0.034730723,-0.033046608,-1.170246244,-1.046690524,-1.8958417109999999,-2.125185346,-2.6940620969999998,-2.566740666,2.450018708,1.058305433,-9.32960853,-9.608780075,-6.6088361429999996,-12.10435221,-9.609064232,-8.717009987,-6.628344824,-4.894434212,-1443.8175518675707 -1771,1771,V117F,-0.188603312,-0.01185563,-0.03228895,-1.048876452,-1.859549574,0.089330663,0.041944521,-0.419151145,-0.052388069,-0.000779093,-0.022932167000000003,-0.063102807,-0.0014750920000000001,-0.694003426,-1.4037494780000002,-1.794613104,-1.924486044,2.064150368,1.576902693,-7.688964812999999,-7.261733582000001,-4.750369385,-11.56991686,-7.709894912999999,-7.152909325,-6.167704493,-3.2416700360000004,-1441.353017359972 -1772,1772,V117I,-0.264380752,-0.02920765,0.056501333,-0.049630350999999996,0.022859979,-0.009719234,-0.065094785,-0.463666719,-0.06694679,0.027903845,-0.086319145,0.06593376599999999,0.047068899000000004,-0.010976191000000001,-0.08828451,0.076875851,-0.031155894,1.114094106,2.7185885560000003,-1.7665006769999998,-1.233026207,-0.7732630229999999,-2.908008606,-2.447022835,-1.471182716,-3.072235679,-0.578043005,-1456.1268431446515 -1773,1773,V117H,-0.289175098,-0.026007544,-0.250962872,-1.640489799,-2.170829267,0.028951614,-0.064845118,-0.513505078,0.142667504,-0.025152627,-0.02686246,-0.127544045,-0.374381698,-1.447331093,-1.8336485040000001,-2.28830346,-2.053355074,0.710398312,0.708163689,-12.16490238,-11.27475385,-8.348230751000001,-18.58385271,-12.89511638,-9.722558227999999,-8.435883383,-6.316306537000001,-1455.4918952835724 -1774,1774,V117K,-0.314088284,-0.094016622,-1.227326892,-1.775715455,-2.743585555,0.048729117999999995,-0.011429462,-0.616747106,-0.367976785,-0.067092974,-0.12094027,-1.115719431,-1.338934353,-1.767470189,-1.78396072,-2.7053525689999995,-2.78181854,2.569394654,1.1861232240000001,-11.77331802,-11.00674554,-9.195935226,-15.643878400000002,-13.41667705,-9.603353874,-8.795120501,-7.59899137,-1455.1647197105922 -1775,1775,V117M,-0.24221695399999998,-0.06286596,-0.036932776,0.048201832,-0.048577407999999996,-0.028879732999999998,-0.011139061,-0.473294847,-0.284639579,-0.027378655,-0.09835326400000001,-0.087616954,0.013751403,0.019427763,0.076975901,-0.08107607900000001,-0.016078737,1.4355039180000002,2.458437854,-4.363642732,-4.042321251000001,-3.356096565,-5.572183731,-4.242629311,-4.604982803,-5.326074086,-3.197302179,-1449.2697661030106 -1776,1776,V117L,-0.238267232,-0.021159241000000002,0.024611372000000003,0.01605092,-0.058099032,-0.020830975,-0.041196216,-0.435338248,-0.11787688199999999,0.043942275,-0.086260757,0.049325767,-0.00010302299999999999,0.047415753,-0.015313914,-0.010972009,-0.105226054,1.185372534,2.546179649,-1.5366615630000002,-0.507659531,-0.8648358840000001,-2.666406036,-2.114310829,-1.530095535,-2.5656178730000003,0.22134431899999998,-1450.356687634252 -1777,1777,V117N,-0.32362586600000004,-0.046714637,-0.017821474,-1.321835129,-2.185462835,0.082775303,-0.039109859,-0.608141872,-0.460730839,0.042462565,-0.13589183900000001,0.079938528,-0.115581475,-1.165148653,-1.478521605,-2.144423718,-2.226501952,0.293690638,0.703575332,-10.22056292,-9.215030731,-6.933738625,-14.49957343,-11.64967973,-8.804792068,-7.004085511,-4.725911779,-1449.0230797762051 -1778,1778,V117Q,-0.374484991,-0.113015164,-0.043925760999999994,-1.51255185,-2.298832998,0.01228646,-0.11930809099999999,-0.62966189,-0.14017870300000002,-0.070041534,-0.15598879300000001,-0.056011887999999996,-0.031839634,-1.254506941,-1.7705967580000002,-2.607362668,-1.9903033280000002,0.954681013,0.7539637929999999,-10.34271522,-9.846376663,-8.172675468,-13.49672191,-11.7785806,-8.419221481000001,-8.082229509,-5.919210967000001,-1456.7497267574072 -1779,1779,V117P,-0.282371759,-0.055102390999999994,-0.023587482000000003,-1.1312305329999999,-1.988141729,0.021275363,-0.052658825,-0.5120846929999999,0.04635364,-0.016095122,-0.094109659,-0.02752038,-0.019654583,-0.7190926670000001,-1.543368399,-1.945114552,-2.031168906,1.878424839,1.435540398,-8.74989317,-9.146503532,-6.739240585,-10.21970612,-9.334212524,-8.309803085,-5.847463461,-4.28899689,-1440.7551243724301 -1780,1780,V117S,-0.348059451,-0.035935456,-0.28899662,-1.568728596,-2.625799367,0.023947219,-0.141448093,-0.554670808,0.080372727,0.00389917,-0.075770082,-0.172310849,-0.40568239100000003,-1.435725411,-1.70173178,-2.43806578,-2.813532953,1.0908471659999999,0.750603818,-10.37309728,-8.974818557999999,-7.7403716739999995,-14.07290837,-11.35054575,-9.726842072,-7.170111636000001,-5.234485493999999,-1443.5541198179126 -1781,1781,V117R,-0.24361180100000002,-0.11642260300000001,-1.3025670870000001,-2.105439961,-2.851083992,0.055374350999999995,-0.049218023,-0.43800557799999995,-0.10942657,-0.013825151,-0.219020054,-1.261835015,-1.3432991580000002,-1.866251895,-2.344628026,-2.563802119,-3.138365864,2.719713343,1.25561952,-10.26244764,-9.830498306,-8.016289116,-14.15769828,-11.63069751,-7.67705497,-6.915723326,-4.487000931,-1451.2757411720231 -1782,1782,V117T,-0.250115225,-0.029834127999999998,0.012580353,-0.010530528999999999,-1.3706346219999999,0.014738635,-0.063904121,-0.436326329,-0.048098706,-0.018617994,-0.041050261,-0.005479869,0.030640574,-0.03461359,0.013552531999999999,-1.218751656,-1.5225175880000001,0.791332732,1.346513606,-7.932260651,-7.3525056,-6.1326936110000005,-9.979522179,-9.792545494,-6.404036369,-5.806539921000001,-4.179871568,-1451.8710444825701 -1783,1783,V117W,-0.255943221,-0.07443053,-1.351495715,-2.25605126,-2.962481988,0.082008652,-0.035083687,-0.476802755,0.022862882999999997,-0.018388764,-0.130472295,-1.337376396,-1.365615033,-1.961098431,-2.551004089,-2.978162057,-2.9468019180000002,0.676915488,0.066440147,-6.81026353,-5.538782013,-5.907137848,-10.82712364,-6.731381027,-5.04689312,-5.245307703,-2.573251214,-1454.4138326016255 -1784,1784,V117Y,-0.341380559,0.018609143999999998,-0.034203576,-1.394499607,-2.304200425,0.01260048,-0.125092714,-0.557668403,-0.14017870300000002,0.030374065,0.006844223000000001,0.082006953,-0.150414105,-1.287463246,-1.5015359680000002,-2.057854539,-2.5505463109999997,2.363392742,1.566767692,-8.398606474,-8.399777885,-4.581695366,-13.35265824,-8.276664719,-7.38223616,-5.916726252,-2.124789941,-1444.3003335571848 -1785,1785,R118A,0.08617433699999999,0.036147797,0.054661962,0.036302631,0.057780066,-0.030544937999999997,0.08239150599999999,0.089957168,-0.113598084,0.005040887,0.067254706,0.049513357,0.059810565999999996,-0.018988636,0.091593898,0.025219403999999997,0.090340727,1.129499537,2.631264114,2.608249808,2.0674316409999998,1.33406282,4.326858444,2.398596985,2.9142991489999996,0.05331638599999999,-0.30335846699999997,-1456.6445022951812 -1786,1786,R118C,0.18278330199999998,0.082868515,0.089045377,0.082955726,0.022429658999999998,0.06474849,0.201817594,0.163749009,-0.062667992,0.058436287999999996,0.10730074099999999,0.066608316,0.11148243699999999,0.047041677999999996,0.11886977300000001,0.0064979619999999995,0.038361356,1.362070184,2.808701961,-4.961308159,-5.524642592999999,-4.908453377,-5.097004501,-4.093757217,-5.182683105,-6.382058056,-7.535893982999999,-1454.3594137523323 -1787,1787,R118E,0.026017109,0.07171736,0.039529654,0.012008208999999999,0.049050117000000004,0.012406799,0.059711985999999995,-0.007677769,-0.046873724000000005,0.036373947999999996,0.107060771,0.009189876,0.069869431,-0.040645994,0.064662411,0.022645952,0.075454281,1.319069709,2.77049399,-0.060092778,-0.681121918,-0.43458886700000005,0.004133987,0.23882345600000002,0.572289452,-1.782542163,-1.1480329409999999,-1448.4554044944234 -1788,1788,R118D,0.02625042,-0.008629554000000001,0.027487297999999997,-0.005125526,0.030534581,-0.018908223000000002,0.059340779,-0.00683994,0.481400053,0.029966262,-0.047225369,0.04894379,0.006030805,-0.004127965999999999,-0.006123085,-0.015306891999999999,0.076376053,1.305479997,2.628227821,-0.851754948,-1.174133881,-1.29758036,-0.946357597,-0.152816086,-0.687886818,-1.49805114,-1.726436461,-1448.1562628229149 -1789,1789,R118G,-0.016353398,0.007237049000000001,0.016317243999999998,0.001971505,0.015036121999999999,0.029744833999999998,0.04553641,-0.078243206,-0.036100363999999996,0.017650653,-0.0031765559999999997,0.0066446019999999995,0.025989886,-0.010657668,0.014600678,0.020148635,0.009923609,1.257875546,2.740139213,2.42835004,1.753671661,1.117619255,3.419369751,3.0142286680000003,2.836860863,1.3589743980000002,-1.007176965,-1455.0320693082176 -1790,1790,R118F,-0.010086076999999999,-0.008922288,0.031678691,-0.00084538,-0.006853186,-0.046255189,0.017741545,-0.037913699,0.073475823,-0.018917714,0.0010731389999999999,0.026057801000000002,0.03729958,-0.018401478,0.016710718,-0.029195698,0.015489326000000001,1.261964956,2.478207252,-2.652566455,-3.590400818,-2.510470673,-4.472113533,-0.88971225,-1.800135002,-2.9794445539999996,-3.623692675,-1445.0227670902386 -1791,1791,R118I,-0.008065667,0.041606408,0.043735705,0.043729638,-0.472002342,0.087401726,0.053570593,-0.069701927,-0.067414427,0.049823183,0.033389632,0.064504984,0.022966425,0.039629253999999996,0.04783002099999999,-0.335535374,-0.608469309,0.9722927,1.639672269,-3.630767558,-4.32337056,-2.5682676769999997,-3.772211945,-2.8185148389999997,-4.671472771,-4.073915932,-3.211824015,-1440.422109611798 -1792,1792,R118H,0.06998799,0.02950257,0.07556677,-0.020113119,0.046338758,-0.039179097,0.06757181799999999,0.07240416200000001,-0.00036610699999999996,-0.000801822,0.059806961,0.018867698000000002,0.132265842,-0.041561794,0.001335557,-0.022527103,0.11520461800000001,1.276755325,2.5206573519999997,-1.7799450469999998,-3.265339722,-2.004851181,-1.9855953219999998,-1.0735904459999999,-0.570348564,-2.897583917,-2.8704265060000003,-1455.4759761807509 -1793,1793,R118K,-0.12431767099999999,-0.055915783,0.01440222,0.032936827,-0.042341403,-0.053301075,-0.038321845,-0.210313497,-0.193210606,-0.058148767999999997,-0.053682797000000004,0.031089862000000003,-0.002285422,0.062878735,0.0029949190000000004,-0.021870465,-0.06281234,1.199371564,2.585908336,-1.2274138209999998,-2.028689102,-1.3852400130000002,-0.9048282009999999,-1.060304016,-0.7580077740000001,-1.573049189,-1.262806123,-1456.796274616383 -1794,1794,R118M,-0.020730537,-0.009793038,-0.012474862,-0.016744207,-0.024256937000000003,0.019387667,0.036246334,-0.077707407,-0.036339052999999996,-0.03359527,0.014009193999999999,-0.03632429,0.011374566000000001,-0.047594450999999996,0.014106038000000001,-0.042827215999999994,-0.005686658000000001,1.321427578,2.414619047,-4.22474585,-4.225494652,-2.982794655,-4.803388603,-3.74320961,-5.368841728,-3.807379678,-3.777869985,-1444.67706083972 -1795,1795,R118L,0.036529635,0.028522917999999998,0.07093257,0.03463397,-0.023411341000000002,-0.023285623999999998,0.067052425,0.006006844,-0.088475255,0.008423469,0.04862236599999999,0.029636287999999997,0.11222885199999999,-0.0028280809999999997,0.07209602,-0.03419249,-0.012630191,1.063767873,2.354444695,-2.9905242419999998,-4.022805885,-0.744396683,-3.386797646,-2.213631485,-4.58498951,-2.909018028,-1.461244213,-1440.7753685978241 -1796,1796,R118N,-0.018257246,0.048629175,0.052406512999999995,0.042307845999999996,0.040624438,-0.046720335,0.026298151000000002,-0.062812643,-0.098383544,0.066950968,0.030307381,0.104571415,0.00024161,0.023372939,0.061242752000000004,0.052310998,0.028937877,1.162116382,2.789158065,-1.870366907,-2.683146286,-2.278595535,-1.8045489959999998,-1.493231323,-1.092312393,-3.024305013,-3.58612226,-1455.4947921074927 -1797,1797,R118Q,0.055458725,0.033137688,0.11043060099999999,0.089627048,0.110618312,-0.10126669699999999,0.055743762,0.055173687,0.036947915,0.045067875,0.021207499999999997,0.107073451,0.11378775099999999,0.054092652000000005,0.125161444,0.060884887,0.160351736,1.105709139,2.8104465239999996,-1.3078020609999998,-1.86728627,-0.799366371,-1.8247462840000002,-2.057256424,0.009645042,-2.338629866,-2.0911685419999997,-1455.7027807524428 -1798,1798,R118P,0.03162797,0.013754581,0.04145012,-0.475285336,-1.724867907,0.029083611000000002,0.08681659800000001,-0.023560658999999998,-0.009085164,0.026438304,0.001070857,0.046332280999999996,0.036567958,-0.21141090399999998,-0.7391597679999999,-1.857268035,-1.592467778,1.1428302,1.328309473,-4.204341599999999,-4.525827843,-4.360792603,-3.671159897,-4.022478142,-4.4414495160000005,-4.718240439,-5.323603949,-1449.7997694043443 -1799,1799,R118S,0.063759247,0.043443772,0.04895046,0.063100099,0.09075071300000001,-0.004211205,0.114919641,0.012598851999999999,0.078380518,0.015771137,0.071116407,0.045178804,0.052722116,0.037998827,0.088201371,0.031807283,0.149694143,1.069916017,2.663732896,1.7485659969999998,1.3212009279999999,0.540397499,2.547294426,1.931762077,2.402175056,-0.376137692,-1.2099188859999999,-1456.2403136407956 -1800,1800,R118T,0.053708148,0.019056112,0.018983507,0.02255016,0.015904985,0.003673225,0.09837404699999999,0.009042248000000001,-0.131125372,-0.001719595,0.039831819,0.015743663,0.02222335,-0.009028314,0.054128632999999995,-0.020515891,0.05232586,1.160497553,2.4378376840000002,-1.062213403,-1.1225927279999999,-1.509501381,-0.441777153,-1.1628148729999999,-1.074380882,-2.8583738210000003,-3.2849989,-1450.9625593749806 -1801,1801,R118W,0.017369632,0.07646682099999999,0.057532255,0.069627325,0.068141592,0.009984405,0.083503656,-0.048764392999999996,0.061505468,0.044902379000000006,0.10803126199999999,0.019072551,0.095991958,0.029530175,0.109724474,0.029403334,0.10687985,1.070977887,2.607428009,-4.707745654,-5.198376587,-3.869727547,-6.208966713,-3.738145645,-4.52351178,-4.62424297,-4.591170078999999,-1452.6934581259266 -1802,1802,R118V,0.019249195,0.025173664,0.044162056,0.018263055,-0.175151046,0.031916276,0.054700097999999996,-0.016201708000000002,-0.011515468999999999,-0.011926443,0.062273771,0.06610550400000001,0.022218607999999997,-0.006275302,0.042801411,-0.178853345,-0.17144874699999998,1.321244515,2.083570169,-3.001961591,-3.7188921280000002,-2.92480423,-2.41732473,-2.5176491469999998,-3.431137718,-3.24651071,-4.011718749,-1441.1048202584498 -1803,1803,R118Y,0.105373281,0.040647812,0.067758179,-0.006526441,0.022056821,0.012739138999999998,0.161771559,0.048975002000000004,-0.041478693,-0.042281124,0.12357674699999999,0.000468971,0.135047387,-0.034902182999999996,0.021849301,-0.068042977,0.112156619,1.3921976440000001,2.4332827740000003,-2.341448868,-3.676400009,-2.48361554,-4.356644783,-0.8637984009999999,-0.326785606,-3.560906808,-2.484003953,-1451.6240657600574 -1804,1804,E119A,0.027917422,-0.014252553000000001,-0.041742661,0.020854251,-0.286135695,0.061169193,0.058886846,-0.0030520029999999997,0.09099220699999999,0.018368618,-0.046873724000000005,0.055265518,-0.13875084,0.018443246,0.023265255,-0.279481195,-0.292790195,1.640244272,2.228530588,-1.68036879,-1.041278931,-1.8619745030000001,-2.003862015,-1.675052582,-1.819675919,-2.930924778,-1.6687352830000002,-1450.8588433223777 -1805,1805,E119C,0.063467143,-0.055601904,0.030413898999999998,-0.9618721859999999,-2.1288413530000003,0.13529427800000002,0.059121452000000005,0.067812834,0.302996022,0.030125346,-0.141329153,0.10798889699999999,-0.047161099000000005,-0.635704107,-1.288040265,-1.999425346,-2.258257359,1.791020157,1.409306824,-8.461060606,-7.017796204,-7.894433495,-9.320650803,-8.619765862000001,-9.45265667,-8.4950091,-6.548781087999999,-1460.402337545529 -1806,1806,E119D,-0.02953949,0.015749702,0.0046832209999999996,0.050086507999999995,0.050682024000000006,-0.056811682,0.018353202,-0.077432181,-0.11676206,0.12015654099999999,-0.08865713800000001,0.10298699800000001,-0.093620557,0.09828792800000001,0.0018850879999999998,0.028303368,0.073060679,1.1060094409999999,2.723212628,-1.697410106,-1.1668536379999999,-1.5903912580000001,-1.451865479,-2.279337151,-1.998603004,-3.5903736060000004,-0.287518404,-1457.010759291239 -1807,1807,E119G,0.08882199800000001,-0.020923239,-0.041675409,0.027915199999999998,-0.211259948,0.061434353,0.083606703,0.094037292,-0.07234292,0.015106902,-0.056953379000000005,0.047360835,-0.13071165199999998,0.035709092000000005,0.020121306999999998,-0.17471410699999998,-0.247805789,1.187118251,2.014754366,-3.717300769,-3.15910347,-3.364646149,-4.2241701130000004,-3.684490883,-4.154093231,-4.844490384,-3.7958123269999997,-1450.3234069920145 -1808,1808,E119F,-0.11601630199999999,-0.046292864,-1.04424611,-2.17094009,-2.810730425,0.09012743699999999,0.024359346,-0.25639195,0.040553398,-0.012066131,-0.080519597,-0.872675434,-1.215816785,-1.7558363730000002,-2.5860438059999997,-2.629471381,-2.991989469,2.308789484,1.091189955,-8.788129854,-7.234076247999999,-6.9253349,-10.21703087,-8.918424095,-10.64578316,-7.264344361,-4.629417234,-1454.9608205673285 -1809,1809,E119I,0.022108467000000003,-0.590078825,-1.4518714959999999,-1.883245091,-2.332929806,0.035654626,0.07846399700000001,-0.034247063,0.0030370370000000002,-0.56794674,-0.612210909,-1.49651819,-1.4072248019999998,-1.892128346,-1.8743618359999998,-2.8626733669999997,-1.803186245,2.972448482,1.26469962,-8.443008742,-6.503017258,-7.274406425,-9.010527183999999,-8.441376052999999,-10.98571679,-7.693987913,-5.58848318,-1450.40229098266 -1810,1810,E119H,-0.049829862999999995,-0.073091612,-0.035737184,0.007486847,-0.909007435,0.086480449,-0.021189298999999998,-0.078470427,0.09099220699999999,0.011352828,-0.15753605099999998,0.057662512,-0.129136879,0.01457309,0.000400604,-0.7372252979999999,-1.080789571,0.7568045990000001,1.400119071,-6.718770551,-6.011270592000001,-6.575578011,-6.395580863999999,-6.847009132,-7.764414154,-6.481936295,-4.900684251,-1459.3497509644367 -1811,1811,E119K,-0.06832025900000001,-0.010494547,-0.028575661000000002,0.0017721929999999998,-1.414133549,0.08607703400000001,0.06338697900000001,-0.200027497,-0.063909753,0.053256934000000006,-0.07424602799999999,0.060516377999999996,-0.11766769999999999,0.103258935,-0.099714549,-1.610272919,-1.217994179,0.428811974,1.304524708,-4.236303406,-3.520186157,-4.116255905,-4.384792305,-3.820021767,-5.340260895,-5.111732891,-2.645466687,-1457.033689018339 -1812,1812,E119M,0.07336774,0.007963481,0.047043215,0.044637252,-1.63992501,0.022757912999999998,0.020850139,0.12588534099999998,-0.328727576,0.09085733,-0.07493036900000001,0.10622843400000001,-0.012142004,0.024485497000000002,0.064789006,-1.695655313,-1.584194706,0.232308177,1.297717247,-7.126239142,-5.726748512,-6.319437027,-8.479501549,-7.277422256,-7.828086365,-6.72140024,-5.418231904,-1452.2202015556395 -1813,1813,E119L,-0.013107576000000001,-0.028284042000000002,-0.773277697,-1.782227899,-2.748624492,0.009621956,-0.0033194640000000003,-0.022895687999999997,0.069983826,-0.018177868,-0.038390216,-0.582917849,-0.963637544,-1.752131628,-1.81232417,-2.625766636,-2.8714823469999997,1.8875736,0.8916013690000001,-8.111070361,-6.127335304,-6.84986721,-8.990299294,-8.466697754,-10.12115224,-7.2462287860000005,-5.58848306,-1447.2332319710404 -1814,1814,E119N,-0.120584419,-0.039268838,-0.073064934,-0.00890441,-0.608434947,0.102338391,0.038506997,-0.279675834,-0.024991687000000002,-0.009026778000000001,-0.069510897,0.012504633999999999,-0.15863450199999998,-0.002215165,-0.015593653999999998,-0.36396681200000003,-0.852903082,0.770655303,1.5215985330000001,-5.480216544,-4.872452866000001,-5.234579094,-5.839473305,-5.04298188,-6.411595573,-6.222045655,-2.562557682,-1458.489682501182 -1815,1815,E119Q,0.067221893,-0.016648171,-0.021277993999999998,-0.024171667999999997,-0.055457407,0.033561602,0.072002661,0.062441124,0.008176675999999999,0.011670804,-0.044967146,0.048767262,-0.09132325,-0.026441495,-0.021901841000000002,-0.049598853,-0.061315960999999995,1.198641987,2.368205152,-1.638491614,-1.0980145190000001,-1.812986115,-1.5868096919999999,-1.64097541,-2.053672333,-3.748466943,-1.439937795,-1459.76052542869 -1816,1816,E119P,-0.046665984,-1.0562393490000002,-1.78039466,-2.052073253,-2.8951336789999997,0.058644552999999995,0.065300174,-0.158632141,0.233915103,-1.0529775909999999,-1.059501106,-1.941120384,-1.6196689359999998,-2.081458035,-2.022688471,-3.085426811,-2.7048405460000002,2.9947873360000004,0.929476379,-8.891905582,-7.694458282,-8.528895508,-9.58120414,-9.023863731,-9.631106247,-9.71395341,-9.407631909,-1455.0236995974556 -1817,1817,E119S,-0.011048661000000001,-0.015268338000000001,0.013415975,0.032591402,-0.36466954100000004,0.080931762,0.072550667,-0.094647989,0.117821774,0.020995642000000002,-0.051532317,0.055726628,-0.028894677999999997,0.014100915,0.051081888,-0.270566868,-0.458772213,1.340198313,1.951727311,-4.23065016,-3.454488388,-4.408773605,-5.382678696,-2.7464368739999996,-5.160873238,-5.393249125,-3.127076967,-1452.8409163295291 -1818,1818,E119R,0.10725186800000001,-0.026716762999999998,-0.040606919,-0.30301448,-1.7349685469999998,0.084484672,0.041286252999999995,0.173217482,0.040687088999999996,0.000950152,-0.054383677000000005,0.033731002999999996,-0.11494484099999999,-0.118437624,-0.48759133600000004,-1.96699974,-1.5029373540000002,1.109945065,1.320443283,-4.307724948,-3.488356247,-4.966280853,-2.899113945,-5.384098732000001,-4.800774963,-5.814927518999999,-3.0035188039999996,-1452.5586146796122 -1819,1819,E119T,-0.043812727999999995,-0.050105737000000004,-0.034074847000000005,-0.439345945,-1.904197339,-0.00197845,0.025871339,-0.113496795,0.10984029,0.0024755520000000002,-0.102687025,0.017552782,-0.085702475,-0.19099163600000002,-0.687700254,-1.9179554,-1.8904392780000001,1.164230687,1.326061778,-4.774644252,-3.326310326,-4.511568993,-6.240483215,-4.002391434,-5.792467293,-6.252612284,-2.49204337,-1454.3442052109167 -1820,1820,E119W,0.114758286,-0.055911817999999995,-1.11421463,-1.8799838780000002,-2.695865472,0.031206706,0.19320356800000002,0.036313002999999996,0.052595816,0.099543384,-0.211367019,-1.012098821,-1.216330439,-1.916799439,-1.8431683159999999,-2.966525705,-2.425205238,2.187481187,0.924705605,-9.301594263,-8.048908127,-8.285021011,-9.650076889,-10.65793174,-9.866033546,-7.093385975,-4.00566663,-1456.0124429678544 -1821,1821,E119V,0.054693492999999996,-0.147576713,-1.4574484109999999,-1.58575783,-2.23644673,0.041332488,0.038918066,0.07046892,0.03300026,-0.07929504,-0.215858386,-1.529722161,-1.385174661,-1.9102685719999999,-1.261247088,-2.922206277,-1.5506871830000002,2.673647093,1.094959223,-6.592684632999999,-4.885019386000001,-6.064036591,-7.462946396,-6.603810814,-7.947609977999999,-6.951979112,-4.502924053,-1451.7618528488092 -1822,1822,E119Y,0.007885101,-0.011861743999999999,-0.574234846,-1.4032725330000002,-2.12499127,0.061426217000000005,0.107448004,-0.09167780199999999,0.183644397,0.035115863,-0.058839351,-0.37787158,-0.7705981120000001,-1.402478497,-1.4040665680000002,-2.3942128169999997,-1.8557697219999998,2.199158356,1.263602691,-8.516695237999999,-7.010555946,-7.148606316,-9.521410561,-8.796994949,-10.10590842,-6.916279053999999,-3.767088222,-1457.2495142645203 -1823,1823,L120A,0.02299752,-0.013729086000000001,0.010712556000000002,-0.06949089,-1.656683027,0.028566243999999998,-0.048126712,0.09412175099999999,-0.28792695,0.00031612599999999996,-0.027774298,-0.034713744,0.056138855,-0.063100748,-0.075881031,-1.722725199,-1.590640854,0.756881033,1.3128743520000001,-6.779326322999999,-10.21371678,-5.063780914,-5.985266387999999,-5.482024605,-7.1518429260000005,-5.5046985070000005,-2.640429182,-1442.61175822746 -1824,1824,L120C,-0.101415136,-0.035107395,0.015466852,-0.218310167,-1.956852199,0.068187271,-0.10916250599999999,-0.093667766,-0.157928415,-0.024750926,-0.045463863,-0.029902821,0.060836525,-0.096890654,-0.339729679,-1.8271588619999999,-2.086545535,0.838262957,1.3108779179999999,-9.26758956,-11.820203300000001,-7.9149526670000006,-10.4553448,-8.57997422,-7.567472816,-8.546422005,-5.314053546,-1452.336346196942 -1825,1825,L120E,0.06409161099999999,-0.827785131,-1.827650557,-2.3347754259999998,-2.6890916860000003,0.003009156,-0.03647872,0.164661942,0.113943352,-0.79526412,-0.860306142,-1.513840221,-2.141460893,-2.435134096,-2.234416756,-2.669124015,-2.709059356,2.276898686,0.5246398,-12.82088511,-15.08617767,-10.8400903,-13.770397899999999,-11.97115508,-12.43660458,-11.01015823,-10.46629924,-1440.807383084204 -1826,1826,L120D,0.074830658,-1.28167561,-1.706435665,-2.0423491940000003,-2.635226081,0.021659634,0.0373184,0.112342916,-0.099936468,-1.115962242,-1.4473889780000002,-1.9853575980000002,-1.427513732,-2.342380042,-1.742318345,-2.576369962,-2.6940822,2.140236116,0.05332438,-12.27562912,-14.31069049,-10.3235269,-13.42916042,-10.806689,-12.50807878,-10.13489741,-7.910881902000001,-1441.1118748821318 -1827,1827,L120G,0.032231806,-0.057572306,-0.911409424,-1.7300821869999998,-2.8045577510000004,0.038178103,-0.005341756,0.06980536799999999,-0.052163685999999994,-0.043639088,-0.071505523,-0.86985331,-0.952965538,-1.70103253,-1.7591318440000001,-2.4210985469999997,-3.1880169539999996,2.705890477,1.431829424,-12.25745872,-14.95840295,-9.967017372,-13.12923133,-10.53961652,-12.69302542,-9.730856201,-7.2385577329999995,-1444.4766647215001 -1828,1828,L120F,-0.143083964,-0.070924935,-0.036593797000000004,-1.320975046,-1.8853995069999998,0.014019566,-0.072724628,-0.21344329899999998,-0.176324814,-0.08573392699999999,-0.056115942,-0.061889319000000005,-0.011298275,-1.351385529,-1.2905645620000001,-2.138217417,-1.632581597,2.532095335,1.6166678159999999,-7.474878329,-8.921046371000001,-5.998237221,-8.518871803,-7.169236961,-6.76699929,-7.813022942999999,-5.475027282,-1452.5199420424178 -1829,1829,L120I,-0.093062184,-0.033820483,-0.033177166,0.006083796,-1.593683033,0.030188813999999998,-0.018884115,-0.167240253,0.025002269,-0.018894333,-0.048746633,-0.016407917,-0.049946414,-0.010497431000000002,0.022665022000000003,-1.856210659,-1.331155407,0.9061646990000001,1.31388891,-4.420372446,-2.762978355,-4.785669693,-5.967418137,-3.733488632,-4.852307411,-5.797769323,-2.278558895,-1450.3722984665073 -1830,1830,L120H,-0.022094599,-0.061687775,-0.096858537,-1.5221624669999998,-2.436765693,0.053375293,-0.06435376,0.020164563,-0.16688325699999998,-0.030332187000000004,-0.09304336199999999,-0.098367396,-0.095349677,-1.575365158,-1.468959776,-2.5497177669999997,-2.323813618,2.492908042,1.454956032,-9.823517642,-12.09361266,-7.385449371,-12.39152749,-9.390818474,-7.856180222000001,-8.445615887999999,-5.994888232999999,-1459.2687324229628 -1831,1831,L120K,-0.071753928,-1.041858582,-2.090939601,-2.378398123,-2.7327143830000002,-0.01130161,-0.041366793,-0.10214106199999999,-0.577057722,-0.984354745,-1.099362419,-2.28947867,-1.8924005309999998,-2.470409856,-2.286386389,-2.7043997760000003,-2.76102899,2.003800039,-0.19557209,-12.30462457,-14.22532285,-10.445853,-13.90957055,-11.00230421,-11.94007227,-11.01015823,-10.46629924,-1455.6728205578402 -1832,1832,L120M,-0.035090458,-0.08743104199999999,0.020338493,-0.014890736000000002,-0.31533879,0.035218895,-0.009748616,-0.060432299,-0.12341756300000001,-0.031796822,-0.143065262,-0.0047638,0.045440786,-0.08853473,0.058753259,-0.30009818,-0.330579399,1.645720261,2.145514509,-4.683491951000001,-6.013356056,-4.850749702,-5.353772354,-3.6519196010000003,-3.547662041,-7.099233077999999,-3.770962523,-1447.374390328303 -1833,1833,L120N,-0.166891696,-0.074843088,-1.083139164,-1.921642949,-2.926474207,0.008922233,-0.07400726,-0.259776132,0.268040318,-0.092699934,-0.056986242,-1.117983163,-1.048295164,-2.0392770380000003,-1.804008859,-2.8753269489999997,-2.977621464,2.240315851,0.8817686379999999,-12.29841585,-14.57026831,-10.18499422,-14.13408275,-11.48103595,-11.12169802,-11.01015823,-10.46629924,-1450.6578629016876 -1834,1834,L120Q,-0.104077028,-0.07492291,-0.694368538,-1.668685239,-2.673516497,0.036116577999999996,-0.118269995,-0.089884061,-0.232562033,-0.062568608,-0.087277211,-0.61136972,-0.777367355,-1.5749526569999999,-1.76241782,-2.712032564,-2.635000429,2.004604547,1.009126636,-11.75469424,-14.05481695,-10.04402764,-13.54320495,-10.36904958,-10.76237208,-11.01015823,-10.46629924,-1446.0655844858848 -1835,1835,L120P,-0.20267906,-1.448452995,-1.73058359,-2.141294259,-2.779291773,0.026533965,-0.083219994,-0.322138125,-0.00041981099999999997,-1.5724385159999998,-1.324467473,-1.8996125819999998,-1.561554597,-2.089687147,-2.192901371,-2.67355563,-2.8850279160000003,-0.17015593,-0.9797462109999999,-12.81945266,-14.889889499999999,-11.15148304,-13.60405658,-11.79561839,-12.65621578,-11.01015823,-10.46629924,-1454.240000060061 -1836,1836,L120S,-0.129646444,-0.006451923,-0.14635512,-1.459169986,-2.488623444,0.041843557999999996,0.00296084,-0.262253727,-0.11031850300000001,0.013191378,-0.026095224,-0.08511278800000001,-0.207597452,-1.344003575,-1.5743363959999999,-2.2051642069999997,-2.77208268,2.281240774,1.4301092180000001,-10.49130075,-12.89355479,-8.259694817,-11.0396804,-9.542776299,-10.72079745,-8.628326632,-6.8715029979999995,-1450.6540762390941 -1837,1837,L120R,0.025515432,-1.564780399,-1.7247857919999998,-2.0466849590000002,-2.676454953,0.024367838,-0.014921218,0.065952082,-0.109276494,-1.815593525,-1.313967272,-1.7405062080000002,-1.709065375,-2.018347407,-2.07502251,-2.854397318,-2.498512588,-0.034350843,-1.08917561,-12.20881358,-14.399301999999999,-10.15873238,-14.62317763,-11.14048022,-10.72237565,-11.00429669,-10.44368496,-1455.6543817282654 -1838,1838,L120T,-0.148518615,-0.054859969,-0.050781527,-1.236380863,-2.41338899,0.045855872,-0.024277875,-0.272759355,0.06846796299999999,-0.057697217,-0.05202272,-0.045169590999999995,-0.056393462000000005,-1.063963954,-1.408797771,-2.234822287,-2.591955693,2.10986661,1.3969355490000002,-9.810568321,-11.57798013,-8.117021362000001,-10.34708717,-9.033279045,-9.977473892,-8.627261715,-3.609139158,-1448.959578438662 -1839,1839,L120W,-0.073859018,-1.120271313,-1.674850023,-1.9394297999999999,-2.643231062,-0.081661496,-0.043160305,-0.10455773,-0.099936468,-1.2552977459999999,-0.985244879,-1.8614516669999999,-1.488248379,-2.042382852,-1.8364767469999999,-3.1794627589999997,-2.106999365,3.274460714,1.06544634,-10.93678209,-12.20441442,-9.316925919,-13.09140387,-10.46100502,-9.610161217,-9.598967032000001,-7.238559795,-1456.6709054089151 -1840,1840,L120V,0.022592211,-0.034971125,-0.033748045,-0.749995458,-1.783373826,0.019700017,-0.02112445,0.06630887099999999,-0.022639365,-0.03478392,-0.035158329,-0.067708891,0.00021280099999999998,-0.437509459,-1.062481456,-1.776018249,-1.790729402,1.68802588,1.4382670359999998,-6.121450857999999,-5.411335167000001,-5.318412331,-7.063089249,-5.965684044,-6.848733498,-6.275142444,-2.403078808,-1455.2807867741212 -1841,1841,L120Y,-0.19271619,-0.067237223,-0.976410861,-2.069672038,-2.901109553,-0.035069896,-0.138149458,-0.24728292100000002,0.094638197,-0.081807966,-0.052666479,-0.987292098,-0.9655296240000001,-2.196252007,-1.943092069,-2.907363181,-2.894855924,1.9427055469999999,0.685554087,-9.252887592999999,-10.44423698,-7.110301193,-12.03281886,-8.863742226,-7.813338707000001,-8.984130329,-5.543246839,-1454.723397770431 -1842,1842,C121A,0.08904931599999999,-0.051104409,-0.016551268,-0.03542283,-1.3671009619999999,0.113933064,-0.060064549,0.238163181,-0.05996154,-0.029643719,-0.072565098,-0.059738022,0.026635486,-0.00020346400000000002,-0.070642195,-1.111149637,-1.623052287,0.7699435659999999,1.354085498,-9.043801167,-7.44146653,-8.434157897999999,-12.06368692,-7.945701004,-9.333993485,-6.076570661,-0.423668018,-1456.4621201180853 -1843,1843,C121E,-0.38730118700000005,-0.5574972420000001,-1.6747039590000001,-2.1232695969999997,-3.29997929,0.138492817,-0.099225645,-0.675376729,-0.046996563,-0.43425619200000004,-0.6807382909999999,-1.66993764,-1.6794702769999998,-2.068476263,-2.178062931,-3.046647825,-3.553310754,2.781318508,1.0109896520000001,-14.72908192,-13.00862576,-13.79711082,-18.29942474,-14.82673293,-13.71351537,-10.09918734,-7.014622481,-1460.4659425504506 -1844,1844,C121D,0.21479204899999998,-1.165109903,-1.696132149,-1.9400130530000002,-2.63960149,0.199178537,0.013463566000000001,0.416120531,-0.198264238,-1.331960468,-0.998259338,-1.708537425,-1.6837268719999998,-1.764653367,-2.115372738,-2.7428249289999997,-2.53637805,3.9322031760000002,1.751915249,-15.418200699999998,-13.17122884,-15.8404536,-18.83912002,-14.96226876,-14.27793228,-11.08138346,-9.465434804,-1460.4852390149608 -1845,1845,C121G,-0.241937707,0.013519752,-0.019227142,-0.77877055,-1.7945430709999999,0.150088741,-0.05195228,-0.43192313299999996,-0.102299371,-0.001209022,0.028248525,-0.071658556,0.033204272,-0.33901008899999996,-1.2185310109999998,-1.884931691,-1.704154451,1.505712542,1.3758996559999999,-11.54551561,-10.141869999999999,-11.1756465,-14.22047592,-11.23001231,-10.95957333,-7.370933,-4.026302292,-1461.7811359898187 -1846,1846,C121F,-0.074983199,-0.58500169,-1.54289959,-2.627401113,-2.977504548,0.11021342199999999,0.026360593999999998,-0.17632699100000002,-0.007488021,-0.454548041,-0.7154553379999999,-1.6776977240000002,-1.408101456,-2.636903653,-2.617898572,-2.916105211,-3.038903885,1.4543412180000002,0.077050227,-11.13681386,-11.91545425,-10.32494781,-11.68280393,-11.364832400000001,-10.39603092,-8.191645538,-4.53904156,-1454.7348959259689 -1847,1847,C121I,0.259461097,0.00710009,0.032175185,-0.656352659,-1.655882633,0.033758197999999996,0.032520903,0.48640129,-0.323202975,0.045457874,-0.031257694,0.005090409000000001,0.05925996099999999,-0.292501931,-1.020203386,-1.8705565659999999,-1.4412086990000001,1.383009406,1.356589223,-11.24472802,-10.51708639,-10.29750864,-15.45507884,-10.97010925,-8.983856979,-6.147742755,-1.1326044309999999,-1447.3760203225538 -1848,1848,C121H,0.245762969,-1.008258141,-1.989788875,-2.160605761,-2.933258216,0.157037449,0.054128558,0.437397379,-0.077379192,-1.204210754,-0.812305527,-1.8383520130000002,-2.141225737,-2.049369915,-2.271841607,-3.173669513,-2.692846919,3.104662032,0.953945461,-13.60248731,-12.85469775,-13.90513334,-14.56083838,-14.83281078,-11.858956300000001,-11.08138346,-9.465434804,-1465.4226707867347 -1849,1849,C121K,-0.34705847,-1.7639901869999999,-2.032630988,-2.0586476069999997,-3.1473116689999996,0.10340280800000001,0.001442819,-0.6955597590000001,0.055665779000000006,-2.018135274,-1.5098451000000002,-2.248584195,-1.81667778,-2.3047001369999998,-1.812595076,-2.8849316910000002,-3.409691647,-0.7667220229999999,-1.109007334,-14.91392062,-13.02578659,-14.68414422,-17.83433099,-15.31583733,-13.70950399,-11.08138346,-9.465434804,-1463.3159532840364 -1850,1850,C121M,-0.357090377,-0.014821632,-0.021657572000000003,-0.031270103,-1.306918993,0.047801085,-0.015693186,-0.698487567,-0.113943352,-0.047996465999999995,0.018353202,-0.09943939,0.056124247,-0.037940453,-0.024599752000000003,-0.9104280779999999,-1.703409907,1.0730850140000001,1.4439148419999999,-11.3720801,-10.82752172,-10.36049347,-15.44360423,-10.984762400000001,-9.244018668999999,-6.984676546,-2.0005924530000003,-1456.4218995203264 -1851,1851,C121L,-0.274144408,-0.00364386,-0.028326804,-0.153440919,-1.6218186190000001,0.05121568,-0.030056167999999998,-0.518232647,-0.028636553999999998,-0.060252387000000004,0.052964667,-0.131614388,0.07496078099999999,-0.054391052,-0.252490786,-1.838188287,-1.40544895,0.9615390690000001,1.31623328,-9.27140817,-8.954845261000001,-9.071960662999999,-13.2588564,-9.148336562999999,-5.923041962,-5.586063383,-0.280640812,-1454.0099796401337 -1852,1852,C121N,0.067136036,-0.172269063,-1.523141251,-2.145503129,-2.918155585,0.158242551,0.023355083999999998,0.11091698800000001,-0.101354225,-0.072471825,-0.2720663,-1.5182057269999998,-1.528076774,-1.933343611,-2.3576626469999997,-3.0576432089999996,-2.77866796,0.8861469040000001,0.052084602,-11.77903896,-9.782613403,-11.61645774,-14.00282105,-11.88408625,-11.60921635,-8.49840483,-4.7841468019999995,-1462.2963706841692 -1853,1853,C121Q,-0.281436902,-0.010642893,-1.033263262,-1.9762299509999999,-2.763864018,0.146684539,0.011581033999999999,-0.574454837,-0.05154419,-0.113600046,0.092314261,-0.946108959,-1.120417565,-2.051442923,-1.9010169780000001,-2.029614486,-3.49811355,3.893253459,2.469946035,-13.86988745,-11.68733726,-14.08540994,-17.3102149,-13.91311222,-12.35336292,-9.145917698,-5.44339499,-1460.0479144798592 -1854,1854,C121P,0.014326252,-1.1707316540000001,-1.435815141,-1.895162396,-3.318329849,0.148917406,0.004487110999999999,0.024165392999999997,0.007760084,-1.5589726919999998,-0.782490615,-1.92564136,-0.945988921,-1.9594809069999999,-1.830843884,-2.93765247,-3.699007228,-0.425027163,-1.007267713,-15.58216019,-13.98711913,-15.27742196,-18.6552596,-15.16515134,-14.82584893,-11.04661982,-9.256621153,-1461.4420942889992 -1855,1855,C121S,-0.004262668,-0.032590156,-0.061782751,-1.129522757,-2.140735839,0.13235694,-0.020355916,0.011830581000000001,-0.021919967000000002,-0.045099001,-0.02008131,-0.128704409,0.005138907,-0.887250888,-1.371794625,-2.196415669,-2.085056009,2.048854253,1.408475585,-8.284762036,-7.8530419160000005,-7.194481049,-10.08126069,-7.365001717,-8.930024811000001,-5.40203406,-2.4142472230000003,-1462.738050123211 -1856,1856,C121R,-0.122144979,-1.3863653040000001,-1.743061725,-1.556369895,-2.98414135,0.18495450100000002,0.006456412,-0.25074637,-0.099932638,-1.588786801,-1.1839438070000001,-1.911989776,-1.574133674,-1.875351664,-1.237388126,-2.967466579,-3.00081612,-0.17867688699999998,-1.084714557,-15.01716115,-12.8946364,-15.36389944,-18.2371652,-15.125829800000002,-13.46427489,-11.07550393,-9.444781489,-1461.555542793125 -1857,1857,C121T,0.087605024,-0.010107627,-0.629777312,-1.894506356,-2.611475847,0.13991848,-0.007830071999999999,0.18304011899999997,-0.0027929,-0.01619398,-0.004021274,-0.510628628,-0.748925996,-1.654198342,-2.13481437,-2.570221998,-2.6527296959999997,1.808952273,0.8969425940000001,-10.81346519,-9.291862457,-10.28919936,-13.52349158,-10.45933512,-10.50343742,-7.443044345,-3.642841996,-1453.1180219976231 -1858,1858,C121W,-0.31389370699999997,-1.342967234,-1.840516085,-1.936758155,-2.747270968,0.139367785,-0.05045695,-0.577330463,-0.100440882,-1.635086821,-1.050847647,-2.3426569969999997,-1.338375173,-2.00083293,-1.87268338,-2.501883238,-2.992658697,-0.052308379,-1.052172302,-14.70164459,-13.964830599999999,-14.65707964,-16.89547982,-14.73827728,-13.25255561,-11.08138346,-9.465434804,-1462.1766124698333 -1859,1859,C121V,-0.158676462,0.024574349,0.011321338,-1.439136199,-2.614484462,0.10073091699999999,0.039221286,-0.35657421,-0.032273306,-0.026572017000000003,0.07572071400000001,-0.05240148,0.075044156,-1.3436716380000002,-1.53460076,-2.452176969,-2.776791955,0.784408654,0.7245042079999999,-12.54662394,-10.8514162,-12.78869063,-16.4584889,-12.49167668,-10.14284729,-6.27722098,-1.625096725,-1445.0806884546764 -1860,1860,C121Y,0.047350641,-1.318099174,-2.075009417,-2.201848718,-2.941027778,0.14922196599999998,0.077393558,0.017307723,-0.210853365,-1.52309098,-1.113107367,-1.846293955,-2.3037248790000002,-1.9693566869999999,-2.4343407480000003,-3.026709495,-2.855346061,3.549455075,1.144476971,-11.52922771,-12.26616351,-11.2321983,-11.579736500000001,-11.9909801,-10.57706013,-9.358709401,-5.253733566,-1457.0697386227548 -1861,1861,S122A,0.24178902800000002,0.014265926000000002,0.014197302,0.017726278,-0.020963348,-0.021860242000000002,-0.07727714299999999,0.560855199,,0.049056704000000007,-0.020524853,-0.0014922720000000002,0.029886876,-0.002413747,0.037866303,-0.022953799,-0.018972897,1.295753468,2.63461228,-0.468063541,-0.9094229970000001,-0.35873782299999996,0.332229744,-1.009562325,-0.394824303,-2.312838131,1.1383991759999998,-1467.095038634725 -1862,1862,S122C,0.295501434,-0.016514933,-0.025305624,-0.020250367,-0.640035726,0.04877594,0.162551637,0.428451231,,-0.022536422999999996,-0.010493443,-0.029259877000000004,-0.021351371,-0.000521753,-0.03997898,-0.5146321660000001,-0.765439285,0.867855422,1.4913849430000001,-5.971429757999999,-5.576058472000001,-7.012711632,-6.079024307,-6.869572586,-4.319781792,-6.71498637,-2.967315985,-1456.0444390748162 -1863,1863,S122E,-0.17085546,0.006414537,-0.021761887999999997,0.026649233999999997,0.036991756,-0.014261548,0.067474093,-0.409185013,,0.000935148,0.011893925,-0.06262572599999999,0.01910195,0.035329037,0.017969431,-0.006971860999999999,0.080955373,1.129761546,2.579313822,-0.20031553800000002,-0.6578881839999999,-0.125178635,1.1486866759999999,-0.790706474,-0.576491074,-1.6956628390000001,1.761568381,-1472.793171571102 -1864,1864,S122D,-0.27560054100000003,0.01840403,0.019735145,0.083809573,0.050177167,0.032125816,-0.018137933999999998,-0.533063148,,0.032539446,0.004268613,-0.0023338910000000003,0.04180418,0.078320838,0.089298308,0.060110454,0.040243878999999996,1.094874774,2.7930978239999997,-0.546352617,-1.183285957,0.100588707,-0.077918282,-1.226565208,-0.344582344,-2.5526485,1.0194325370000001,-1467.541411609389 -1865,1865,S122G,0.267659731,-0.0017200289999999999,0.001057512,0.009623286,0.025668662000000002,-0.0037724390000000003,0.061338394000000004,0.47398106799999995,,0.039880992000000004,-0.043321049,0.009261048000000001,-0.007146025,0.036787454,-0.017540883,0.019111992,0.032225332,1.129499537,2.631264114,-4.272196315,-4.309300751,-4.406683655,-3.9191650310000004,-3.353578148,-5.37225399,-4.2684291530000005,-0.9665337909999999,-1464.3456456437707 -1866,1866,S122F,0.223634311,-0.058547854,-0.057664327,-0.08606246099999999,-0.15904294300000002,-0.029089707000000003,-0.063093786,0.510362407,,0.047415730999999996,-0.164511439,0.049316847000000004,-0.164645501,0.030378638,-0.20250355899999997,-0.043411736,-0.274674149,1.197729864,2.450691772,-5.070621295,-5.519624107,-5.394254601,-4.364059868,-4.901599686,-5.173568213999999,-4.559770288999999,-1.210799875,-1464.3388545536436 -1867,1867,S122I,0.38333309299999996,-0.034974694,0.015222868999999998,-0.136142781,-0.154171419,-0.031686699,0.067576124,0.6990900609999999,,0.040318451,-0.110267839,-0.008129338,0.038575076,-0.042909855999999996,-0.229375705,-0.129169277,-0.179173561,1.3237531679999999,2.196593886,-6.495264589,-6.186572525,-7.465992767,-6.7271576,-6.349600517000001,-5.746999535,-4.964815043,-1.6341482790000001,-1469.5033357597422 -1868,1868,S122H,-0.034118307,0.045482842999999995,0.017067295,-0.012360421000000002,0.011127575,0.019762977,0.049651800999999995,-0.117888415,,-0.022894287000000003,0.113859973,-0.041038363,0.075172952,-0.011838168,-0.012882673,-0.023634075,0.045889224000000006,1.327193941,2.559648193,-1.4631342219999999,-1.788205711,-1.1143837509999999,-1.216043495,-1.2692658540000001,-1.9277723009999999,-2.99903092,-0.20073053800000001,-1470.1251019504853 -1869,1869,S122K,0.458420799,-0.134713405,-0.088577747,-0.036015889,-0.070357872,0.007972893,0.112725785,0.804115813,,-0.015252393999999999,-0.254174415,-0.018578482,-0.158577011,-0.007466321,-0.064565457,-0.044879388,-0.095836355,1.359140214,2.486134582,-2.184460385,-3.358229805,-2.60639222,-1.932221634,-1.63794754,-1.3875107269999998,-3.086993337,0.368000111,-1470.289844667539 -1870,1870,S122M,0.211697407,-0.315487525,-0.11627018,-0.19636842899999998,-0.229901572,-0.0029971159999999998,-0.480901039,0.9042958520000001,,-0.059380222,-0.5715948270000001,-0.030298846,-0.202241513,0.012730108,-0.405466965,-0.10933720599999999,-0.350465937,1.33716199,2.267876502,-6.276913095,-6.25337159,-5.806894333,-8.444610039,-5.62410144,-5.255588073999999,-4.878974259,-0.615874059,-1471.0393345854245 -1871,1871,S122L,0.331875076,-0.000562799,0.004137846,-0.026732442999999998,-0.00930864,-0.043199318,0.072995392,0.59075476,,0.0007785310000000001,-0.001904128,0.007673787,0.000601905,0.027049215,-0.0805141,-0.030728976,0.012111697,1.243379167,2.524836693,-4.752742255,-4.374715561,-3.819661934,-7.101070762999999,-5.34078421,-3.127478806,-4.162259458,-0.524134013,-1464.2676210920326 -1872,1872,S122N,0.320454327,-0.003168969,0.023173238999999998,0.043213386,0.028354137,-0.010935186000000001,0.016423602,0.624485052,,-0.012890945,0.006553007,0.042533507000000005,0.00381297,0.019973674,0.066453097,0.021332322999999997,0.03537595,1.227535504,2.729066012,-2.117115833,-2.690763145,-2.2265608830000003,-2.459575127,-1.9188783040000001,-1.289801704,-3.620829591,-0.718997155,-1470.9818965680897 -1873,1873,S122Q,0.24952331100000003,-0.015866081,-0.009192786,-0.053999738,0.031705227999999995,-0.043940702000000005,0.06801950799999999,0.43102711299999996,,-0.017252361,-0.014479801,0.00291218,-0.021297751,0.0063082469999999995,-0.11430772300000001,-0.0063775459999999996,0.069788001,1.266443155,2.720386773,-2.060977135,-1.9704271469999999,-1.312899223,-2.3309226990000003,-2.471541809,-2.219094795,-3.1920795039999996,0.193925428,-1476.0041542411782 -1874,1874,S122P,0.11809733,0.012619677,-0.23945133100000002,-0.88923865,-1.137558841,0.035295834,0.040650184,0.195544475,,0.00224526,0.022994092999999997,-0.41800113,-0.060901530999999995,-1.611457371,-0.167019928,-2.223441825,-0.051675856,2.53270911,1.4797551690000001,-8.071793167000001,-8.280587357,-7.844758499,-8.26466362,-8.242219887000001,-7.726736473,-8.595015477,-6.9941420889999995,-1467.621889467584 -1875,1875,S122R,-0.003072379,0.020958215,0.015684232,0.020640951,0.004943197,-0.008013905,0.057109800999999995,-0.063254559,,-0.022662572000000002,0.064579001,-0.0027313890000000003,0.034099852,0.012808469,0.028473432000000003,-0.052773394,0.06265978700000001,1.378716015,2.53968567,-2.023537766,-1.914387321,-0.6877490390000001,-3.463144691,-1.46534671,-2.587061066,-3.939447523,1.010952053,-1472.1586230709217 -1876,1876,S122T,0.172842962,0.012916523999999999,0.0137892,0.024728273999999998,-0.048347505,-0.02444848,0.005936381,0.339749542,,0.025366199,0.000466848,0.014904175,0.012674225,0.058558463,-0.009101915,-0.029832525,-0.066862485,1.267893708,2.504631358,-2.969045012,-2.438888817,-3.637488983,-3.462279503,-3.2474143680000003,-2.059153389,-3.5087814980000003,1.0980965790000001,-1470.1256133578718 -1877,1877,S122W,0.367604559,-0.048617348,-0.030193547999999997,-0.080856729,-0.065610253,-0.028691743,0.14620867199999998,0.589000446,,0.0027017720000000003,-0.099936468,-0.025093462,-0.035293633,-0.002375619,-0.159337839,-0.099680336,-0.03154017,1.395513414,2.366341084,-7.237980917000001,-7.1118037339999995,-7.737459572000001,-6.803167792999999,-6.7763536989999995,-7.761119788999999,-5.75446124,-2.128534863,-1461.5646017962135 -1878,1878,S122V,0.426733834,-0.038884959,0.065571219,-0.011582772,-0.010096556,-0.031445699,0.137305588,0.7161620790000001,,-0.025087649,-0.052682269000000004,-0.0059369719999999996,0.137079409,-0.023463925,0.00029838200000000003,-0.049051713,0.028858601,1.136327568,2.2667833269999997,-4.515405168,-4.4106712880000005,-6.006736038,-4.609441376,-4.834155624,-2.716021515,-3.795583962,-0.28350528,-1472.2072323232424 -1879,1879,S122Y,0.036594233999999996,-0.028142597000000002,-0.026150289,-0.007976202,-0.017809198999999998,0.006122435,0.03705647,0.036131997,,-0.034832558,-0.021452635,-0.022567438,-0.029733139,0.025267531,-0.041219935,-0.034344716000000004,-0.001273681,1.340955651,2.612253322,-5.121678333999999,-4.970863602,-6.477635902,-4.128093703999999,-3.699550697,-6.332247765,-5.689018936,0.36143618299999997,-1465.8769563175738 -1880,1880,A123C,-0.280185439,-0.004247023,-0.046905697999999996,-0.034296357,-1.28428257,0.083669736,-0.156805433,-0.403565445,0.31122943399999997,-0.031892516,0.023398471,-0.0071759630000000005,-0.086635432,-0.023339686000000002,-0.045253027,-0.9779357759999999,-1.590629364,0.9652358520000001,1.404744514,-11.67593257,-10.08993374,-10.55083051,-12.70024502,-12.45265037,-12.586003199999999,-9.739678394,-6.625083582999999,-1458.595879540313 -1881,1881,A123E,-0.23981918800000002,-0.015990868000000002,-0.009362643,-1.441669809,-2.480116703,-0.025782717,-0.077738011,-0.401900365,0.179127022,-0.005856268,-0.026125467000000003,-0.036236915,0.017511629,-1.0564833409999999,-1.8268562769999999,-2.494428955,-2.465804451,0.79988404,0.755326033,-9.767012602000001,-7.23729052,-8.53442942,-11.43130537,-10.25346146,-11.37857624,-7.351486929,-3.175513342,-1462.2319765132852 -1882,1882,A123D,-0.24768679600000001,0.016535884,-0.658586558,-1.514936134,-2.27741418,0.065728023,-0.038841212,-0.456532379,0.293094974,-0.014330208999999998,0.047401977000000005,-0.525803966,-0.7913691490000001,-1.439023245,-1.590849023,-2.358454919,-2.196373441,2.417369461,1.392352095,-9.140484811,-6.305842079,-8.676863861000001,-10.267077800000001,-9.581106514,-10.87153381,-7.562071424,-4.0278476880000005,-1455.0816443143412 -1883,1883,A123G,-0.260528661,-0.0034585320000000003,-0.027570498,0.011865836999999999,-1.5579455690000001,0.040060509,-0.10542452,-0.415632802,0.215831415,-0.028306654,0.021389591,-0.011264472,-0.043876523,-0.008235165,0.031966839,-1.532332805,-1.583558332,0.854143894,1.3302493690000001,-6.1023016310000004,-3.943840469,-4.943286308,-8.149883513999999,-7.292417595,-6.182080269,-6.156265728999999,-3.8631742160000004,-1456.9866476124153 -1884,1884,A123F,-0.33324564100000004,0.011224287,-0.250954361,-1.39422107,-2.64344777,0.057670803,-0.22414054600000002,-0.442350736,0.247718915,-0.027337083999999998,0.049785657999999997,-0.19332558800000002,-0.308583134,-1.5624768230000001,-1.225965316,-2.628036532,-2.6588590080000003,1.1857535240000001,0.7468140240000001,-12.18665587,-11.66231805,-8.992744476,-14.28416422,-13.75072243,-12.24333016,-8.138436035,-2.99935023,-1446.9663843289018 -1885,1885,A123I,-0.28281536,0.066103649,0.013376095,-0.977584401,-1.679705983,0.010823077,-0.124134829,-0.44149589100000003,0.17478902600000001,0.08894946699999999,0.04325783,0.016985613,0.009766577,-0.7741724240000001,-1.180996377,-1.7563949280000002,-1.6030170380000002,2.18436879,1.6457875419999999,-7.746696703,-7.575559509,-4.827628517,-7.810091948999999,-8.528251946000001,-9.991951591,-6.303298452999999,-4.0662751660000005,-1456.346917798277 -1886,1886,A123H,-0.222591453,0.0060726569999999995,-0.065716493,-1.46797117,-2.266565409,-0.015309103000000001,-0.081360048,-0.36382285700000006,0.24085743,-0.025540623,0.037685937,-0.071483495,-0.05994949,-1.284121285,-1.651821054,-2.24931045,-2.283820368,0.833057151,0.736014051,-11.34389446,-10.28763858,-9.163620857,-11.60489192,-10.06223399,-15.60108694,-8.242547434,-3.804352764,-1460.155239556916 -1887,1887,A123K,-0.318796332,-0.002167327,-1.222976178,-1.9995646759999999,-2.514617711,-0.063986326,-0.191014763,-0.446577901,0.187990482,-0.026377935,0.022043281,-1.008153248,-1.4377991069999998,-1.8173676980000002,-2.181761653,-2.162768104,-2.866467318,3.697827593,2.325580277,-12.30403358,-10.04480191,-9.186185318,-13.98518378,-12.29653608,-16.00746079,-7.979542192,-2.6918373439999996,-1458.7287219623104 -1888,1888,A123M,-0.389051091,-0.027207689,-0.093753905,-1.553111933,-2.704317891,0.046070637000000005,-0.254399159,-0.5237030220000001,0.24057396,-0.014181656,-0.040233721,0.030792535,-0.21830034399999998,-1.3901980719999998,-1.716025794,-2.7246030930000003,-2.6840326880000003,0.676974188,0.711887917,-8.64358615,-8.824457672000001,-6.349230156,-10.44138876,-10.34778276,-7.255071396,-6.783530174,-3.085595402,-1446.9850970166735 -1889,1889,A123L,-0.326070116,-0.000561003,-0.187264404,-1.320231538,-2.310294405,0.05893954,-0.18402865,-0.468111581,0.274890704,0.00421037,-0.005332375,-0.086077645,-0.288451163,-1.383759859,-1.256703216,-2.553069006,-2.067519803,0.766047135,0.7187811390000001,-9.574247033999999,-9.554737723999999,-6.507860336,-10.60663165,-11.62561115,-9.576394318,-6.657953858,-0.500251245,-1443.8063470530324 -1890,1890,A123N,-0.37273222,-0.10686937199999999,-0.011476841000000002,-1.109896215,-2.7013990480000003,0.064470691,-0.212902925,-0.532561514,0.332367328,-0.133139253,-0.080599491,-0.042472061,0.01951838,-0.5662197379999999,-1.653572691,-2.082248507,-3.3205495889999996,1.7122589030000002,1.3699568640000002,-11.14018086,-8.998755005,-10.1639077,-12.48321461,-10.927424900000002,-13.1276021,-7.707709578999999,-4.479306169,-1454.4974012789316 -1891,1891,A123Q,-0.382757312,-0.091981034,-0.13192312,-1.36173126,-2.533981274,0.081510005,-0.232236816,-0.533277807,0.161118336,-0.12884673900000002,-0.055115329000000005,-0.079335839,-0.18451040100000002,-1.264091652,-1.4593708680000002,-2.224916011,-2.8430465369999998,0.99923322,0.756627726,-11.37526737,-9.989266571,-8.981983077999999,-13.51394772,-10.72880686,-13.66233263,-7.3259771460000005,-2.618636681,-1450.1861623516306 -1892,1892,A123P,-0.29544296600000003,-1.303264907,-1.369459938,-1.5287458090000001,-2.277657644,0.061768009000000006,-0.127254148,-0.46363178299999996,0.109867201,-1.72525497,-0.8812748429999999,-1.7626485980000002,-0.976271277,-1.9657505130000001,-1.091741104,-2.987844528,-1.56747076,-0.5273210939999999,-1.028536408,-11.02525557,-10.07382784,-10.06141911,-11.84924564,-12.17361216,-10.96817309,-8.350854372,-4.889756063,-1464.816816452425 -1893,1893,A123S,-0.25770920399999997,0.009110295,-0.014811205,0.011556071000000001,-0.275678578,0.021270194,-0.136060412,-0.37935799600000003,0.181668763,-0.016424983,0.034645573,-0.008990326,-0.020632084,-0.006522961999999999,0.029635104,-0.20039826800000002,-0.35095888799999997,1.311260259,2.041412754,-7.36018342,-6.383967772999999,-6.4935955729999995,-8.412306267,-7.5655041579999995,-7.945543327,-7.091799427000001,-3.1310374089999997,-1461.9843734879978 -1894,1894,A123R,-0.26092956300000003,-0.255169872,-1.4320488230000001,-2.130741892,-2.9599893930000003,0.031329449,-0.11237097800000001,-0.409488147,0.2646768,-0.19687903899999998,-0.313460705,-1.4163487869999998,-1.447748859,-2.038823243,-2.2226605409999998,-2.711582583,-3.208396202,2.61870926,1.060856871,-10.8422903,-8.252465263,-8.575836967,-13.44795206,-9.441289474,-14.49390773,-6.374985589,-2.200517873,-1452.8235891237855 -1895,1895,A123T,-0.125126247,0.00345706,0.008159428,-0.17994204,-1.5781502059999999,0.043713545,-0.09373254,-0.15651995300000002,0.15658201800000002,-0.015201832,0.022115952,0.011412206999999999,0.004906649,-0.09117516,-0.268708919,-1.691848071,-1.46445234,0.876558307,1.323936171,-7.548103804,-6.019906517000001,-6.250928284,-9.485409157000001,-7.490484306,-8.493790756000001,-7.176424602999999,-4.785366407,-1452.0216057733633 -1896,1896,A123W,-0.281376845,0.023298695,-0.613395525,-1.4358704480000002,-2.6040287369999997,0.005447228,-0.14317574800000002,-0.41957794200000004,0.26011591300000003,-0.0031601859999999997,0.049757575,-0.499551266,-0.7272397829999999,-1.588374107,-1.283366788,-2.452288453,-2.7557690210000003,2.32256759,1.259818873,-13.22285313,-11.60270753,-10.2959799,-15.21126812,-14.18517313,-14.81913696,-8.100618754,-3.470832843,-1453.0344707877375 -1897,1897,A123V,-0.220493947,-0.013733802,-0.046557558,-0.046080508,-1.466993592,0.08266781,-0.018667245,-0.42232064799999997,0.182850843,-0.026038743,-0.00142886,-0.03501895,-0.058096165,-0.007036873000000001,-0.08512414199999999,-1.539900443,-1.394086741,0.655303947,1.316725554,-6.858876115,-7.3159490510000005,-4.776024055,-6.953280403,-7.797590598999999,-7.451536469,-6.360495091000001,-3.574983415,-1449.9178601745516 -1898,1898,A123Y,-0.280417522,-0.059911254000000004,-0.030064585,-1.6064922130000001,-2.2452688309999997,-0.001969492,-0.156881915,-0.40395312899999997,0.271199218,-0.13811466,0.018292153000000002,0.005232019,-0.065361189,-1.467849572,-1.7451348530000002,-2.563372504,-1.9271651580000002,0.7652826340000001,0.7112710859999999,-11.74887883,-10.70017768,-8.65470108,-11.64724389,-12.05583648,-15.68643504,-7.999499028,-1.627886676,-1449.6121540465392 -1899,1899,A124C,-0.011634577,-0.017851698,-0.010291103000000001,0.034677989,-0.9191722929999999,0.050435432,0.013957158999999998,-0.037226313,0.029709084,0.026703897999999997,-0.062407294,0.029588992999999997,-0.050171198,0.110700666,-0.041344689,-0.615274866,-1.22306972,0.571892388,1.386581536,-10.24298311,-10.65081633,-12.1924863,-7.745605727999999,-9.61734063,-11.00866655,-7.908494062000001,-5.079621127,-1459.0071557941847 -1900,1900,A124E,-0.038411508999999996,-0.8963758009999999,-2.073460304,-2.468136461,-2.721775029,0.064547819,-0.026702534,-0.050120483,0.06833848599999999,-0.682755028,-1.1099965729999999,-2.046636421,-2.1002841869999997,-2.178244903,-2.758028018,-2.430280839,-3.013269218,0.8217612679999999,-0.45077020700000003,-11.8486739,-11.70452618,-13.75140367,-9.762016578999999,-11.06749381,-12.95792925,-10.31075578,-9.737882625,-1463.096387923928 -1901,1901,A124D,-0.09018777900000001,-0.91483705,-1.7196120990000001,-2.033362845,-2.468590365,0.07118087,-0.08767097900000001,-0.09270457800000001,0.076058108,-0.81857446,-1.011099639,-1.871206692,-1.568017505,-1.905905161,-2.160820529,-2.5558811059999997,-2.3812996230000003,3.721601301,1.745826015,-12.35735396,-12.42372642,-13.95276357,-10.48531007,-11.99137843,-12.93359134,-10.31777227,-9.781867988,-1455.0142517408822 -1902,1902,A124G,-0.0027064859999999997,0.057796238,0.000145854,0.027665711000000003,-1.301310383,0.05461385,0.007662751,-0.013075722,0.04140334,0.055089234,0.060503242,0.022150737,-0.021859029,0.054080289000000004,0.001251133,-1.2228733109999999,-1.379747455,0.636832294,1.332523842,-6.81752935,-7.647071999,-7.354613831,-4.697074593,-7.307185425,-7.081700905,-7.058506488,-4.496111818,-1459.8234672273975 -1903,1903,A124F,-0.027110456,-1.391661003,-2.039531853,-2.371738641,-2.926407205,0.013374345,-0.028052171,-0.02616874,-0.094704317,-1.4607407380000001,-1.3225812670000001,-2.0942436630000003,-1.984820042,-1.9248221490000001,-2.818655132,-2.477888081,-3.374926328,0.347011226,-0.895631023,-16.15089619,-16.40157903,-18.29852361,-14.83403253,-14.50169779,-16.718648,-10.31777227,-9.781867969,-1462.4199442770332 -1904,1904,A124I,0.020092405,0.046904718,0.0672466,-0.860383755,-1.774834631,0.090141551,0.04529354,-0.00510873,0.031281034,0.021859316,0.071950119,0.029480406,0.105012794,-0.422251014,-1.298516496,-2.32264696,-1.2270223009999999,1.4265071040000001,1.280433052,-9.165272189,-10.68651352,-11.30078786,-6.1992850189999995,-7.949799057000001,-9.689975487,-6.179921998999999,-3.511875505,-1452.7912341053598 -1905,1905,A124H,-0.03561949,-1.4380660319999998,-2.0268643,-2.1890970569999997,-3.0642546489999996,0.102773805,-0.011478255,-0.059760725,-0.080665682,-1.6150813990000001,-1.261050665,-1.78482703,-2.268901569,-1.819525499,-2.558668614,-3.071561435,-3.056947863,0.088695815,-1.0041316409999999,-13.77943121,-13.67799036,-14.79833383,-10.776526400000002,-12.50733798,-17.136967499999997,-10.31777227,-9.781868017,-1465.990933876019 -1906,1906,A124K,0.012278438000000001,-1.552713314,-2.0301051930000003,-2.458254744,-3.012923308,0.060417198,0.049038529000000004,-0.024481653,-0.08171551,-1.4604015780000001,-1.64502505,-2.035912556,-2.024297829,-2.1675210380000003,-2.74898845,-2.7205869689999997,-3.305259646,0.276536292,-0.9192750009999999,-13.23416453,-12.93221961,-14.73641473,-10.16145316,-12.1447118,-16.19602334,-10.31777227,-9.781867995,-1467.9994932657573 -1907,1907,A124M,-0.063068996,-0.003268258,-0.014727211,0.027366344,-1.8479598659999998,0.019126091,-0.047494325,-0.078643666,0.058836012,0.058684178,-0.065220693,0.055677948,-0.08513237,0.086701178,-0.03196849,-1.60519355,-2.090726181,0.414995159,1.304244792,-8.963420807,-10.36260567,-11.86793983,-5.932270409,-7.6753243939999996,-8.97896373,-6.300651534,0.16170137099999998,-1450.4352300921455 -1908,1908,A124L,0.003243602,0.014383091,-0.16920965300000002,-1.53856309,-2.491934679,0.011818531,0.01393761,-0.007450406999999999,0.017757,-0.024067934,0.052834115,-0.174618395,-0.16380091,-1.259976709,-1.81714947,-2.3271474619999997,-2.656721895,1.184126442,0.7973790340000001,-12.75066125,-13.00720635,-15.15957541,-9.397731627999999,-11.29902584,-14.88976703,-7.693431397,-4.880356316,-1438.4474551728927 -1909,1909,A124N,-0.039626014,-0.008471771999999999,-0.028157772999999997,-1.207287424,-2.7414766839999998,0.015503517,-0.036035639,-0.043216388,-0.041601659,-0.029751527000000003,0.012807984,-0.07147410000000001,0.015158554,-0.8347344459999999,-1.5798404019999999,-2.2007137340000003,-3.282239633,1.790684639,1.339065403,-10.6062467,-10.34700438,-12.3388198,-7.862363212999999,-10.39596574,-12.08708037,-8.010214371,-4.99488381,-1459.150402059313 -1910,1910,A124Q,-0.05570425,0.044020779,-0.877571678,-1.851658241,-2.8327192389999998,0.086177941,-0.06602153,-0.04538697,-0.03298095,0.019766112,0.06827544599999999,-0.5651314789999999,-1.190011876,-1.6719163769999998,-2.0314001040000003,-2.577164827,-3.08827365,1.878655473,0.9166395270000001,-12.82643978,-12.754561,-13.977384900000002,-10.14203616,-11.78095783,-15.477259,-10.12751286,-8.788685144,-1460.6143715255894 -1911,1911,A124P,-0.040167367,-1.507453586,-1.8890531330000002,-2.102559946,-2.842762441,0.040570557,-0.033665618,-0.046669116,-0.043785475,-1.580527939,-1.434379232,-1.7996440040000001,-1.978462261,-1.8273563519999998,-2.37776354,-2.353550137,-3.3319747439999996,-0.037768281,-1.003528998,-11.74818231,-12.28343485,-12.97845091,-9.607790572999999,-11.17090613,-12.70032908,-10.31777227,-9.781868054,-1461.675332855899 -1912,1912,A124S,0.003944871,0.032996437,-0.01380044,-0.014520593,-0.166790065,0.022708655,-0.0007364089999999999,0.008626151,0.014726153999999998,0.043625708,0.022367165,-0.030297945,0.002697065,0.009615455,-0.03865664,-0.127621375,-0.205958755,1.540928459,2.447448777,-4.570665341000001,-4.335074066000001,-5.41764975,-3.269036613,-5.129985802,-4.701580475,-4.955573663,-1.558094527,-1452.944444946479 -1913,1913,A124R,-0.021502245,-1.450598755,-1.849036898,-2.212339794,-2.826507129,0.048507135,-0.005208739,-0.03779575,0.0023197879999999997,-1.551848695,-1.349348814,-1.744142921,-1.953930875,-1.8196354609999998,-2.6050441269999998,-2.812034086,-2.840980172,0.057161815,-0.9403973440000001,-12.76864804,-12.83098136,-13.31063694,-10.02874359,-11.69906257,-15.97381574,-9.484012134,-6.9606561870000005,-1462.9382329289801 -1914,1914,A124T,0.000719217,0.02123136,-0.007647773,0.021103466,-0.065903937,0.029218228,-0.006012639,0.007451073000000001,0.13944099699999998,0.066929433,-0.024466712999999998,0.009987303000000001,-0.025282849,0.042784322,-0.00057739,-0.032283877,-0.09952399599999999,1.270488892,2.533330658,-2.1556347369999997,-2.22340197,-4.0198521419999995,-0.36787730399999996,-1.877604225,-2.289438042,-3.405556116,-0.809660258,-1460.8827556073666 -1915,1915,A124W,-0.015929685,-1.538998013,-1.7218423840000001,-1.871475424,-3.152292824,0.042997717000000005,-0.00702903,-0.024830339,-0.074706783,-1.604930001,-1.473066024,-1.56579186,-1.8778929080000002,-1.697400341,-2.0455505069999997,-2.773345018,-3.5312406289999996,3.990469557,1.77616925,-15.122767000000001,-15.23706037,-17.13106564,-12.85037509,-13.47403239,-16.92130152,-10.31777227,-9.781868041000001,-1465.3353541633114 -1916,1916,A124V,-0.018007089,0.052014685,0.016972908000000002,0.030278532,-1.107471463,0.019667096999999998,0.0077378740000000005,-0.043752052,0.023896711,0.07866748900000001,0.025361881,0.029620782999999998,0.004325033,0.080564472,-0.020007408,-0.84262122,-1.372321706,0.10941661300000001,1.317462885,-7.77839187,-9.537791602999999,-9.901490677,-5.698830536,-7.175420654,-6.57842588,-6.679351416,-3.792301065,-1453.4822749593295 -1917,1917,A124Y,0.107512755,-1.657628385,-2.063686512,-1.918772045,-2.822925611,0.039033983,0.13006011,0.0849654,-0.02596662,-1.5050719730000002,-1.810184796,-2.013636161,-2.1137368619999997,-1.8442146469999998,-1.9933294419999998,-2.6983105739999997,-2.947540647,3.6661911810000003,1.30648619,-16.2577343,-15.79048249,-17.97996777,-14.38175153,-14.37147392,-18.76499578,-10.31777227,-9.781868022000001,-1455.0206222105771 -1918,1918,I125A,-0.066218315,-0.02517663,-0.03068767,-1.371419929,-2.202247019,-0.006927925,0.065395883,-0.197832512,-0.186011717,-0.09774527699999999,0.047392018,-0.07909796,0.01772262,-1.062871417,-1.67996844,-2.392808387,-2.01168565,1.151955893,0.8277126440000001,-9.632787195,-10.4586629,-11.85987718,-7.99991008,-7.784791779,-10.06069404,-7.133038135,-4.038124583,-1447.445422173012 -1919,1919,I125C,-0.085918485,0.023420327,-0.02902827,-0.040319375,-0.9684338779999999,-0.049620542999999996,0.014301577,-0.186138547,-0.17057713,-0.017195359,0.064036013,-0.020493871,-0.037562669,-0.029334441,-0.051304309000000006,-0.93943662,-0.997431135,0.7237552840000001,1.3664607990000002,-12.67294516,-13.83719751,-14.60306833,-11.87865926,-11.53440368,-11.51139702,-8.706265344,-6.381182717000001,-1450.712750137318 -1920,1920,I125E,-0.087453285,-0.759172385,-2.04802089,-2.212835244,-2.8223329510000004,0.029572399,0.07154856,-0.246455129,-0.140257257,-0.68500464,-0.83334013,-2.230979969,-1.86506181,-1.953431069,-2.472239418,-2.862198189,-2.782467712,1.17711777,-0.34382865700000004,-13.15275744,-13.3660434,-13.57445417,-12.06144122,-12.95555928,-13.80628915,-8.472607369,-5.290135811,-1464.570837404579 -1921,1921,I125D,-0.043250388,-1.23294631,-1.846684855,-2.297547593,-2.81996692,-0.009370877,0.084816478,-0.17131725399999997,-0.089828108,-1.114677691,-1.351214928,-2.017200344,-1.6761693659999999,-2.089899462,-2.505195723,-2.426569814,-3.2133640260000003,3.498822347,1.2872072959999998,-15.45085988,-15.85219949,-16.96023816,-14.21911049,-15.23976995,-14.982981299999999,-10.44602202,-9.899372265,-1461.286767885089 -1922,1922,I125G,-0.085113422,-0.623324248,-1.7214663680000002,-2.114614389,-2.841845031,0.006625474,0.052978254,-0.22320509800000002,-0.12112134699999999,-0.596861318,-0.649787177,-1.770678779,-1.672253956,-1.991041448,-2.238187329,-2.836465903,-2.8472241589999996,3.1418186269999997,1.252099801,-13.67901249,-12.22365531,-15.41863157,-13.0977311,-13.47898462,-14.17605985,-8.260474514,-4.271797873,-1446.593121371232 -1923,1923,I125F,-0.089519974,-0.046757140999999995,-1.39250929,-2.344657527,-2.7595721930000003,0.0028256809999999996,0.045280693,-0.22432064,-0.129425461,-0.126160335,0.032646054,-1.2312586140000001,-1.5537599659999999,-2.261205752,-2.4281093019999997,-2.801996087,-2.717148298,1.253027147,0.17986480600000002,-13.29175462,-14.14558376,-12.92468789,-13.18209433,-13.44737045,-12.75903665,-10.21122244,-8.727994678,-1452.5388324554078 -1924,1924,I125H,-0.064018194,-0.033090676,-0.17304318100000002,-1.724238004,-2.754127506,0.030696402,0.108618837,-0.236655225,-0.298766759,-0.07846025400000001,0.012278903,-0.149246531,-0.19683983,-1.4847577269999999,-1.96371828,-2.183155915,-3.325099097,1.124195569,0.742497521,-15.34487425,-15.44721692,-15.85189713,-14.75411645,-14.92171118,-15.74942957,-10.44602202,-9.899372265,-1456.8239588891156 -1925,1925,I125K,-0.10895137099999999,-1.5485330990000001,-2.170276038,-2.170831092,-3.2663144369999997,0.041149222,0.022168692,-0.240071433,-0.16199365300000002,-1.470494494,-1.626571704,-2.163757524,-2.176794551,-2.090328607,-2.251333576,-2.87415699,-3.6584718830000003,0.448169435,-0.92653349,-14.17258681,-14.86128167,-14.02128481,-12.82601785,-13.89949456,-15.25485519,-10.44602202,-9.899372265,-1448.8512536184862 -1926,1926,I125M,-0.08740421699999999,-0.0021787679999999998,-0.020846168999999998,-0.073686246,-0.156435923,-0.050391452,0.015575136000000002,-0.19038357,-0.09043597699999999,-0.052232374000000005,0.047874839,-0.057767402999999995,0.016075066000000002,-0.053883256,-0.09348923599999999,-0.166106878,-0.146764968,1.479126336,2.235439682,-4.692622585,-5.405469398999999,-4.86990049,-2.79810006,-4.525911736,-5.863731239,-5.04142236,-1.3043486359999998,-1457.362614752259 -1927,1927,I125L,-0.059889110999999995,0.001477955,-0.00032826,-0.010313168000000001,-0.138641855,0.005385777,0.062754299,-0.18253252,-0.177111928,-0.05877724,0.061733149,-0.028143223,0.027486702999999998,-0.011568446000000001,-0.00905789,-0.14662007400000002,-0.130663636,1.458762804,2.272174879,-4.374294254,-5.128769363,-4.159971283,-4.483471321000001,-4.140386772,-3.958872528,-4.172423375,-0.812654203,-1456.7814202327281 -1928,1928,I125N,-0.05297929,-0.026202272000000002,-0.065629432,-1.740376481,-3.007071167,-0.019573786,0.085101654,-0.191060233,-0.23904744,-0.12019612,0.06779157599999999,-0.068528717,-0.062730147,-1.40715287,-2.073600092,-2.864397153,-3.14974518,1.294871011,0.797201422,-12.69898209,-13.0122295,-15.21546893,-11.76786314,-12.267631100000001,-11.23171778,-7.93265264,-5.7566761170000005,-1460.1308771017939 -1929,1929,I125Q,-0.113961714,-0.037409147999999996,-0.998846248,-2.025853157,-3.349302481,0.039589344,0.013010218,-0.240933645,-0.164622079,-0.12220702,0.04738872400000001,-0.8536468070000001,-1.144045688,-1.6984230280000001,-2.353283286,-3.1142746260000003,-3.584330335,2.308399774,1.070785477,-11.77680745,-11.623182400000001,-11.03226245,-10.88130802,-11.8924221,-13.45486229,-7.345021974,-3.634575228,-1469.904492767062 -1930,1930,I125P,-0.077798854,-1.4766592159999998,-1.927895247,-2.247869636,-3.0059348189999997,0.00434125,0.056781372000000004,-0.212379079,-0.208805606,-1.6326629259999998,-1.320655505,-1.973743438,-1.882047055,-2.252497039,-2.243242233,-2.668348637,-3.343521001,0.151369032,-1.067627717,-14.54948802,-15.40013929,-16.18685442,-13.32877854,-13.75698258,-14.07468529,-10.44602202,-9.899372265,-1468.3755916147493 -1931,1931,I125S,-0.048179437,-0.007946613,-0.209213757,-1.773380575,-2.5377802419999997,0.016205812,0.096695553,-0.193054427,-0.16234369699999998,-0.09518305199999999,0.079289826,-0.183281055,-0.235146458,-1.428665184,-2.118095966,-2.629507457,-2.446053027,1.291391193,0.791153126,-11.52292218,-12.04883678,-15.11985659,-10.38802359,-10.16480795,-9.893085968,-7.228587276,-5.227952483999999,-1446.8973070736974 -1932,1932,I125R,-0.092362957,-1.493834196,-2.0401370919999997,-2.4096361809999998,-3.247099866,0.049311093,0.061986396,-0.246712309,-0.194976603,-1.5057219130000001,-1.481946478,-1.948647656,-2.131626527,-2.215166801,-2.604105561,-2.880895872,-3.61330386,-0.038773228,-1.1700025059999999,-14.90523118,-15.27754626,-15.35742747,-13.56438597,-14.0873095,-16.2394867,-10.44602202,-9.899372265,-1453.4715588930994 -1933,1933,I125T,-0.022518601,0.047943911,-0.0027592890000000003,-0.006095356999999999,-1.533516229,0.011945543000000001,0.11271869699999999,-0.157755898,-0.057020278,-0.001361569,0.09724939099999999,-0.017622213,0.012103635,-0.018069937,0.005879223,-1.595489167,-1.47154329,0.6925575340000001,1.315981425,-7.983609261000001,-9.702725815,-10.37699564,-6.019796539,-6.819969376,-6.998558929,-6.17068232,-2.9386510269999997,-1447.875613884069 -1934,1934,I125W,-0.08926104900000001,-1.627393401,-2.172661274,-2.345992298,-3.393020637,-0.026331027000000003,0.055831030999999996,-0.234353129,-0.20516557600000002,-1.813988185,-1.4407986169999998,-2.008940661,-2.336381887,-2.287694262,-2.404290333,-2.895431387,-3.890609886,0.040009433999999997,-1.139187731,-14.648040599999998,-15.63006039,-14.81217919,-13.83116146,-14.26786879,-14.69893316,-10.44602202,-9.899372265,-1460.2226405129768 -1935,1935,I125V,-0.038372132999999996,0.009569356999999999,-0.019422379,-0.039457358,-0.082027902,-0.048501435999999995,0.08943123900000001,-0.166175504,-0.105345494,-0.073285006,0.092423719,-0.054879248,0.016034491,-0.0485214,-0.030393315,-0.098407374,-0.06564843,1.3688381230000002,2.3379272209999997,-2.047635144,-2.0356755069999997,-2.351994377,-2.005875168,-1.8398718719999998,-2.004758797,-4.110159854,-0.643668394,-1460.8911139792763 -1936,1936,I125Y,-0.068701061,-1.252592752,-1.808803546,-2.245651922,-3.116589002,0.035697627999999995,0.09657989300000001,-0.233982014,-0.088170845,-1.403368945,-1.101816558,-1.853593927,-1.764013165,-2.266241107,-2.225062736,-2.6309401830000003,-3.60223782,3.386721034,1.070588895,-14.89165804,-15.6022628,-15.16128007,-14.22550773,-14.67087075,-14.79836886,-10.44602202,-9.899372265,-1448.2723824456334 -1937,1937,T126A,-0.17667349699999998,0.02516144,0.011372337,0.007038443,-0.120109387,-0.028940865,-0.034777551000000004,-0.318569442,0.005589881999999999,0.003542361,0.046780518,-0.018008764,0.040753437999999996,-0.018139434,0.03221632,-0.12316190699999999,-0.117056866,1.3750317619999999,2.206857663,-5.7931175139999995,-4.99081427,-5.499103187999999,-6.02096032,-5.733378197,-6.721331596000001,-4.146223913,-1.4428003169999999,-1450.3065033778548 -1938,1938,T126C,-0.170671271,0.053424704,0.021207442000000003,0.034808558999999996,-0.18049420800000002,0.051298663,-0.014465132,-0.32687741,-0.066769418,-0.022129307,0.128978714,-0.025209718,0.06762460099999999,-0.044825860999999995,0.114442978,-0.273467589,-0.087520826,1.201224261,1.8385216919999998,-11.10441903,-9.374317329,-11.53553254,-12.0258579,-12.34781847,-10.23856892,-6.724662151,-3.430291763,-1455.7541344198398 -1939,1939,T126E,-0.226593963,0.011359515,-0.011120608,-0.021424414,-0.021148682999999998,-0.04611073,-0.069677933,-0.383509993,-0.106197796,0.036863446,-0.014144417,0.003948511,-0.026189726,-0.021818247000000002,-0.02103058,-0.0016149329999999998,-0.040682433,1.242359974,2.550598346,-7.4360719379999995,-6.285330719,-5.827951118,-6.75056414,-10.29507455,-8.021439163,-4.458323879,-2.018964078,-1451.056409865152 -1940,1940,T126D,-0.135070456,0.030407816,0.016024766,0.033439849,-1.327968144,0.021901772000000003,0.034626233,-0.304767145,0.08915615800000001,-0.025161897000000003,0.085977529,-0.069127378,0.10117691,-0.017465956,0.084345654,-1.079401729,-1.576534558,0.662473875,1.344273693,-8.294395633999999,-6.775618446,-9.668968216,-7.239932098,-11.0876373,-6.699822113,-4.614884053,-2.883381151,-1442.3306839228608 -1941,1941,T126G,-0.20265891800000002,0.025132771,-0.008218524,-0.03074706,-0.090434344,-0.034886636,-0.033319193999999996,-0.371998641,-0.06471837700000001,-0.030806115,0.08107165599999999,-0.055496355,0.039059308,-0.07495613,0.013462011000000001,-0.133608651,-0.047260036,1.359925915,2.1595304680000003,-9.182486665,-7.142824554,-7.994976532000001,-10.234038499999999,-10.91756342,-9.623030327,-5.753374696,-2.944078448,-1451.555195692461 -1942,1942,T126F,0.006165254,-0.0047010820000000005,-0.168111795,-2.150199067,-2.7577696539999996,0.07459228400000001,0.038144394,-0.025813886,-0.18987954399999998,-0.036298263,0.026896099,-0.22621001,-0.11001358,-1.773063661,-2.5273344719999997,-2.7021807489999996,-2.8133585589999996,1.259639343,0.727886002,-14.08599279,-11.66260291,-13.55068627,-16.27610898,-17.7742057,-11.16636011,-8.276247201,-6.7211680629999995,-1454.9767547645606 -1943,1943,T126I,0.054975047,0.030746957999999998,-0.041504527,-0.05454051099999999,-0.6284574239999999,-0.080044696,-0.040493251,0.150443344,0.08887405699999999,-0.011003441999999999,0.072497358,-0.020602716,-0.062406338,-0.040973498,-0.068107524,-0.49116353,-0.765751317,0.940488928,1.525378031,-7.728511931,-6.148190926,-9.093715935,-9.060529358,-10.13842004,-4.2017034,-4.497360546,-0.8895317090000001,-1451.030731880106 -1944,1944,T126H,-0.239146334,0.063781465,-0.004860651,-0.001251264,-1.590108896,-0.058663825,-0.055126302,-0.423166366,-0.033648449,0.025202891,0.102360039,-0.001900662,-0.00782064,0.025630136,-0.028132663,-1.5977363180000002,-1.582481473,0.569519494,1.3087406240000001,-12.44205402,-11.35238619,-9.833808563,-11.49268142,-14.26170677,-15.26968714,-6.877052542,-4.659106153,-1451.6229864670895 -1945,1945,T126K,0.01733511,0.023398911,0.011957141000000001,-0.030240171,-1.358378399,-0.064843736,0.016390416,0.018279804,-0.292541885,-0.0272154,0.074013222,-0.01196888,0.035883161000000004,-0.03820093,-0.022279411000000002,-1.240962213,-1.475794585,0.9093670620000001,1.360252077,-11.04969965,-9.591318314,-8.981144516,-10.27202608,-12.63486887,-13.76914048,-6.343623046,-3.0137204410000002,-1448.4739448153414 -1946,1946,T126M,-0.115175431,-0.007546683,-0.061007772,-0.09849358400000001,-0.243990837,-0.043653135,-0.12583976300000002,-0.10451109800000001,-0.252931289,-0.002569797,-0.012523568,-0.036320395,-0.085695149,-0.048807859,-0.148179308,-0.23358025899999998,-0.254401415,1.421229036,2.038108655,-10.56531313,-9.569071037,-10.97642991,-11.91582149,-12.64020019,-7.725043007000001,-6.354604851,-3.815295743,-1448.6300240168348 -1947,1947,T126L,-0.096693993,0.035541718,-0.010968823999999999,0.0010304160000000001,-0.8616577240000001,-0.046596676,0.023362429,-0.216750415,0.0015989589999999998,-0.018677819,0.089761254,-0.050693495,0.028755847,-0.018561561,0.020622392,-0.705767945,-1.017547503,0.868131709,1.4329410059999999,-10.14548396,-9.405060966,-10.993181100000001,-9.426929031,-12.99801671,-7.9042319789999995,-4.988605195,-3.096857965,-1445.9612707006745 -1948,1948,T126N,-0.009998497,0.047442564000000007,0.009316461,0.018008128999999998,-1.293054109,-0.055926693,-0.022355494,0.0023585,-0.083826151,-0.007764649,0.102649776,-0.054309467,0.07294238900000001,0.006685216,0.029331042,-1.3666945959999999,-1.219413622,0.65737133,1.323494795,-9.602508217,-8.343792046,-7.808517845,-9.491787117000001,-12.49008698,-9.878357101,-6.957415086,-4.135898254,-1446.028972065542 -1949,1949,T126Q,-0.278037364,0.0033200179999999997,-0.032037934,0.0010746339999999999,-0.287981456,0.002231299,-0.09146629099999999,-0.464608436,-0.197389145,-0.051920839,0.058560875,-0.018034438,-0.046041429,-0.013355500000000001,0.015504768,-0.241967972,-0.333994939,1.582549604,2.193047553,-9.394827292,-8.883511459,-7.265637672,-8.392173202999999,-10.37076799,-12.06204613,-5.2495347169999995,-1.257722168,-1464.1772095533088 -1950,1950,T126P,-0.05767008,0.01881771,-0.764687577,-1.751438869,-2.750667125,0.013981713,-0.040171266000000004,-0.075168893,-0.12452649699999999,-0.017884181000000002,0.055519600999999995,-0.54003178,-0.989343374,-1.6141709819999999,-1.888706756,-2.651114497,-2.8502197519999997,1.9487310409999998,0.9752429859999999,-12.96601012,-12.04315368,-12.60910185,-13.01417787,-13.805678899999998,-13.35793828,-9.77976323,-9.131236502,-1459.4756923890673 -1951,1951,T126S,0.11817350199999999,0.05207628,-0.03551794,-0.02157785,-0.028377463999999998,-0.011246935,0.018914723999999997,0.21743227899999998,0.006415102,-0.027350463,0.131503022,-0.078035257,0.0069993780000000005,-0.052973375,0.009817675,-0.099893766,0.043138839000000005,1.4890498559999998,2.394101586,-4.383847255,-3.326948158,-3.611209122,-5.1422601089999995,-5.062231842,-4.776587043999999,-4.611230074,-0.964335235,-1455.3695534844883 -1952,1952,T126R,-0.194517857,0.020742066,-0.001751331,0.018190034,-1.4194100180000002,-0.07921840200000001,-0.041646191,-0.347389523,-0.069441308,-0.02500302,0.06648715200000001,-0.018821307,0.015318645,-0.008552750999999999,0.044932819000000006,-1.40808033,-1.430739705,0.49979370100000003,1.315191444,-9.796206619,-10.33786086,-5.930782623,-9.140552422,-9.848872414,-13.72296478,-4.130640631,-0.929608928,-1460.5140120610595 -1953,1953,T126W,-0.22908248899999997,0.027459781000000003,0.0012450039999999999,-1.305275812,-1.963531436,0.048581084000000004,-0.042909647999999995,-0.41525533,-0.123244635,0.022612826000000003,0.032306736,-0.015261058999999999,0.017751066,-1.0241626609999999,-1.586388963,-2.259704776,-1.667358095,0.825755586,0.761792895,-15.30228653,-13.22078146,-15.85339976,-16.18777871,-16.1401834,-15.1092893,-7.4525266960000005,-5.571198613,-1456.7603528639302 -1954,1954,T126V,-0.19846640899999998,0.0203496,-0.014448073999999998,-0.037117988,-0.38237527299999996,-0.029002661000000002,-0.036838407999999996,-0.36009441,-0.0020152910000000002,-0.02119364,0.061892839000000005,-0.030851514,0.001955366,-0.061134528,-0.013101448,-0.296762893,-0.46798765299999995,1.318634597,1.90821595,-7.150633237,-5.983161682,-7.573802505,-8.561071411,-8.021590377999999,-5.613540207000001,-4.7815190030000005,-1.305373847,-1446.349855997134 -1955,1955,T126Y,-0.29396024,0.04063387,-0.037705083,-1.398911126,-2.701306344,0.010168301999999999,-0.11574194199999999,-0.472178537,-0.114977095,0.001442949,0.07982479,-0.052002895,-0.023407271,-0.9016019259999999,-1.896220326,-2.983007358,-2.419605329,0.807378155,0.7760887190000001,-13.65478704,-10.7361521,-12.05254279,-15.80411532,-16.49321675,-13.18790826,-7.2701155879999995,-5.048094289,-1447.3670441186987 -1956,1956,M127A,0.7372199970000001,0.029317033,-0.071418003,-0.06272261900000001,-0.6926908359999999,-0.063705055,-0.021008381,1.495448375,,-0.003451865,0.062085931,-0.014806191000000002,-0.128029814,-0.003512012,-0.12193322599999999,-0.39651343299999997,-0.988868238,1.035528788,1.6292598980000002,-7.082077161,-6.7450818329999995,-7.523826004,-7.563333618,-7.471268532000001,-6.1068758160000005,-6.542859728,-1.391320006,-1453.2173481513746 -1957,1957,M127C,0.11857437800000001,-0.018297834,-0.040678448,-0.017391625,-0.48694673299999996,-0.009454121,-0.058265174,0.29541393,,-0.017858406,-0.018737262,-0.046946969000000005,-0.034409926,-0.030666684,-0.0041165659999999995,-0.33115668,-0.6427367860000001,1.2766628,1.8334368509999999,-10.58717039,-9.447184036,-10.43770061,-10.76744659,-10.96046327,-11.32305745,-8.76576791,-4.460167805,-1451.112623107154 -1958,1958,M127E,0.096189551,-0.016611354,-0.014242088,-0.024533059,-0.163903742,-0.032680028,-0.06691256799999999,0.259291669,,0.046085136,-0.079307844,0.01576864,-0.04425281599999999,-0.007480884,-0.041585234,-0.051374002,-0.27643348100000004,1.16497741,2.371227882,-7.552246407999999,-6.871036591,-7.586551071000001,-8.248684227,-8.113047348,-6.941912803999999,-5.6279224910000005,0.517089235,-1453.9382062284276 -1959,1959,M127D,1.093056988,-0.09596679699999999,0.166986457,0.200758563,-0.936038974,-0.036453617,0.213074825,1.97303915,,0.060374433,-0.252308026,0.036033994,0.29793891899999997,0.0035771170000000003,0.397940009,-0.7862996959999999,-1.085778251,0.725158678,1.386158154,-10.60666189,-9.163905205,-13.4295986,-10.29794485,-9.984998222,-10.15686257,-6.516256971000001,-0.403004927,-1448.201554195024 -1960,1960,M127G,0.315820581,0.021604144,-0.01518756,0.024761447000000002,-1.497130957,-0.039307939,0.017019044,0.614622118,,0.052876664000000004,-0.009668376,0.00601708,-0.036392199,0.040351931,0.009170963,-1.4763386930000002,-1.517923221,0.644506104,1.31673331,-10.35471973,-9.279828117000001,-9.760237656000001,-10.46521534,-11.24045035,-11.02786718,-7.60840406,-3.098645173,-1457.0905256862752 -1961,1961,M127F,-0.036729682,0.009536845,-0.004058365,0.00638292,-0.309422693,-0.006582265,-0.048754267999999996,-0.024705096,,0.027334384,-0.008260694,0.062983416,-0.071100145,0.056641227,-0.043875388,-0.149390382,-0.469455004,1.3655875430000002,2.22789784,-7.1902039570000005,-5.756568871,-6.985108962999999,-7.212079796,-8.330140434,-7.667121719,-4.9124201869999995,-0.339359106,-1459.7405529790558 -1962,1962,M127I,0.08159153799999999,0.010909596,-0.0028349620000000003,-0.0038032990000000004,-0.12632389800000002,0.00738454,-0.022330435,0.18551351,,-0.017562752,0.039381942999999996,-0.011722225,0.006052302,0.013294038000000001,-0.020900635,-0.110721739,-0.141926057,1.3862942759999999,2.307707135,-3.5799967560000003,-3.063875626,-3.282390732,-3.177001747,-5.009045853,-3.367669823,-4.299826274,0.768950719,-1456.4383969474584 -1963,1963,M127H,-0.1267838,-0.002129527,-0.014032138999999999,-0.00283735,-0.7132525,0.003345148,-0.012621743999999999,-0.240945855,,0.018526128,-0.022785182,-0.028887146000000002,0.0008228689999999999,-0.028932892999999998,0.023258192999999996,-0.563783551,-0.862721449,0.965565392,1.5113700069999998,-8.453265498,-5.756870308,-9.507846596,-8.982190681,-10.25468877,-7.76473114,-6.202551862000001,0.11060269,-1455.0985216484405 -1964,1964,M127K,-0.030666195,0.0038294559999999997,0.04983254,0.022735163,-0.578754318,-0.07565506799999999,-0.015807187,-0.045525202,,-0.004224813,0.011883725,0.04525503,0.054410049,0.039408291,0.006062035,-0.311014784,-0.846493851,0.9585498920000001,1.656834925,-6.8882866410000005,-6.14394117,-6.855686172,-7.764972649,-8.718545752999999,-4.95828746,-5.725738405,-0.401553496,-1464.295548834838 -1965,1965,M127L,-0.219845667,0.011461458,0.01146416,0.040917756,0.005314044,-0.023096678,-0.031636807,-0.40805452600000003,,-0.003082868,0.026005782999999998,0.022139267,0.0007890530000000001,0.011718675,0.070116836,0.014403937,-0.00377585,1.197901555,2.649089193,-1.70865825,-0.873971176,-2.149725998,-1.4605851669999999,-2.358745293,-1.7002636180000001,-3.55071335,1.061192272,-1460.719495705096 -1966,1966,M127N,0.191001723,0.046361299,0.031755263,0.047141745,-0.767545404,-0.01430906,-0.07114167099999999,0.453145116,,0.09071156400000001,0.0020110329999999997,0.06375376,-0.00024323400000000002,0.09285723300000001,0.001426256,-0.536981912,-0.998108895,0.5213513679999999,1.386103663,-8.887957298,-8.440184196,-9.246274239,-9.206233192000001,-8.959856293,-8.587238571,-6.276364739,-1.171991946,-1448.9447972867638 -1967,1967,M127Q,-0.256329327,0.027999579,-0.013879313,0.016574106,-0.108822238,-0.098266145,-0.041613344,-0.47104531,,0.019542022,0.036457136,-0.033220814,0.005462189,0.014994394,0.018153817,-0.09121710400000001,-0.12642737199999998,1.3543633819999998,2.335204358,-4.675554074,-4.319172378999999,-4.351906929,-4.466376358,-5.373686371,-4.866628334,-4.433604645,0.9273366,-1467.559750447981 -1968,1968,M127P,-0.127984832,-0.351675808,-1.493384021,-2.107462107,-2.891893956,-0.01092818,-0.047526513,-0.20844315,,-0.26252868100000004,-0.440822935,-1.5285009619999999,-1.45826708,-2.017809133,-2.1971150809999997,-2.960287068,-2.823500844,2.638841342,0.991786266,-11.22992623,-10.30533861,-11.53219071,-10.91125205,-12.19764767,-11.20320213,-9.761802929,-6.678452117000001,-1461.421366637107 -1969,1969,M127S,0.132158108,0.026204992000000003,-0.003291215,0.023630271,-0.5568486460000001,-0.041976245,0.007931769,0.256384446,,0.036167568,0.016242416000000003,-0.010460487,0.0038780579999999998,0.021432809,0.025827733,-0.368013059,-0.745684233,1.118565946,1.696697495,-7.777274414,-7.290417067999999,-6.921976044,-7.7006756670000005,-7.959889488,-9.013413802999999,-6.126012405,-1.5623317190000001,-1455.262842788361 -1970,1970,M127R,-0.142308791,0.024092656,-0.005452492,0.042037900999999996,-0.219904281,-0.047286935999999995,-0.042897912999999996,-0.241719669,,0.029194595,0.018990717,0.027573353,-0.038478337,0.023910643999999998,0.060165157000000004,-0.099496826,-0.340311735,1.4529047730000002,2.433234466,-6.314464351,-5.060274757,-6.377533347999999,-6.212635727,-8.903704277000001,-5.018173645,-4.621488605,0.517028536,-1457.6468237238005 -1971,1971,M127T,0.324975026,0.021246325,-0.049599325,0.010079181,-0.08453091800000001,-0.046856847,-0.050166609,0.7001166609999999,,0.049206442999999996,-0.006713793000000001,0.025256703999999998,-0.124455353,0.035222107999999995,-0.015063746000000001,0.007832779,-0.17689461399999998,1.187722774,2.755023382,-3.700639127,-5.050727287,-3.180319046,-3.347124123,-3.42329026,-3.501734917,-3.8604933439999995,0.40264946799999995,-1444.5869135968387 -1972,1972,M127W,-0.152195719,0.022023213,-0.008344155,0.029861026000000002,-0.06086343599999999,0.015350743,-0.049791455,-0.25459998300000003,,0.027360687,0.016685738000000002,0.032160259,-0.048848567999999995,0.056516910999999996,0.00320514,-0.034595375,-0.087131496,1.4326555980000002,2.691098977,-6.2627130829999995,-5.540571922000001,-4.178261131,-5.468853988999999,-7.24382608,-8.882052292000001,-4.823903016,-0.820240052,-1461.6847412660718 -1973,1973,M127V,0.250143235,-0.008310551999999999,-0.054514981,-0.024613634,-0.026401493999999998,0.00533881,-0.035189452999999996,0.535475923,,0.021807102999999998,-0.038428206,-0.0012979760000000002,-0.107731985,0.006691671,-0.055918938,0.02048114,-0.073284127,1.1759819329999999,2.606005258,-3.392381737,-2.669580376,-3.321936333,-3.078908966,-4.1309446030000005,-3.7605384060000002,-2.5070589659999998,1.5676711890000001,-1453.1097307736054 -1974,1974,M127Y,-0.067259759,-0.031946522000000005,-0.06788897099999999,-0.029167727999999997,-0.200429175,-0.000187081,-0.084796651,-0.049722866,,-0.03564714,-0.028245903,-0.045668754000000006,-0.090109188,-0.04177736,-0.016558095,-0.116378629,-0.284479721,1.4412747909999999,2.315629562,-6.819694019,-5.883712425,-6.485792641000001,-6.890903542,-7.85604039,-6.982021095,-4.395572628,1.420604319,-1458.3345549842343 -1975,1975,S128A,0.016472111,-1.2515645309999999,-2.236337372,-2.114316659,-2.873953259,-0.10901291699999999,-0.061603724000000006,0.094547946,0.049411860999999994,-1.3205511540000001,-1.182577908,-1.993783158,-2.478891585,-2.178191303,-2.050442014,-2.764059806,-2.9838467110000004,0.18561698,-0.78568327,-9.651037715,-9.803297722,-9.69631546,-9.449031242,-9.864269669,-9.442274483,-8.776495975,-9.732748317999999,-1448.6276751924306 -1976,1976,S128C,-0.11140495800000001,-1.6076112669999998,-1.99094189,-2.097380111,-2.662433669,-0.025056216,-0.032390652,-0.19041926399999998,-0.11310659099999999,-1.5685785419999998,-1.6466439919999998,-1.6757482080000001,-2.306135572,-1.773006176,-2.421754045,-2.212746644,-3.112120693,4.218314565,1.9792903919999998,-9.95241906,-9.875566727,-10.08568948,-9.893529465,-10.11184448,-9.795465149,-9.022567354,-11.21585505,-1455.75046364218 -1977,1977,S128E,-0.155754129,-1.722686105,-1.812883866,-2.653002795,-3.20795466,-0.06953229,-0.072499727,-0.23900853100000002,-0.200108315,-1.869608537,-1.5757636730000002,-1.800686944,-1.8250807869999999,-2.462216343,-2.8437892469999997,-3.18278342,-3.2331258999999997,-0.214970295,-1.170388274,-9.919787149,-10.02295014,-9.929194016,-9.915491486,-10.04593493,-9.685365173,-9.055072442,-11.57519656,-1455.829409123864 -1978,1978,S128D,-0.074296849,-1.719326006,-2.2787478880000003,-2.190200569,-2.807621802,-0.135373257,-0.0232954,-0.125298297,0.196626992,-1.853061984,-1.5855900269999998,-2.011384173,-2.546111602,-1.7186710619999999,-2.661730075,-2.564176876,-3.051066727,-0.7636379590000001,-1.043867321,-7.99417059,-8.391711548,-8.263399506,-7.706575043,-7.842781822,-7.766385033,-7.402024052000001,-7.494333591,-1453.3572371872142 -1979,1979,S128G,-0.09230568800000001,-0.033182848,-0.455678036,-1.742475941,-2.500924977,-0.102192718,-0.035967221,-0.148644154,-0.067659977,-0.040500689,-0.025865006,-0.41759514700000006,-0.493760925,-1.5925274,-1.892424481,-2.564014674,-2.437835279,2.098901439,1.091643583,-5.303970528,-5.612216721,-5.315092239,-5.02618837,-5.510173515,-5.056181793,-5.463115737000001,-5.023569633,-1457.6839543837123 -1980,1980,S128F,-0.11857652099999999,-1.498525991,-2.026254384,-2.565343318,-2.881734555,0.03679083,0.0053828,-0.242535842,-0.020923978,-1.7615395669999998,-1.235512415,-1.986808545,-2.065700222,-2.472246685,-2.65843995,-2.715692507,-3.047776602,-0.42379194299999995,-1.081604268,-10.01269843,-10.160211300000002,-10.0693588,-9.854657761,-10.20304729,-9.776217017999999,-9.055072442,-11.57519656,-1451.7348968610168 -1981,1981,S128I,-0.12006068,-1.540195432,-2.122496059,-2.1844637380000003,-3.0404455980000002,0.054247400999999994,-0.04552592900000001,-0.19459543,0.008019176,-1.7419554519999998,-1.338435412,-2.025216376,-2.219775741,-2.0335332619999997,-2.335394214,-3.055130334,-3.025760862,-0.41913391299999997,-1.077378628,-9.969516109,-10.13907819,-9.935002235,-9.822947205,-10.12422798,-9.826324936,-9.055072442,-11.57519656,-1462.4252905179746 -1982,1982,S128H,-0.14796089199999998,-1.610025019,-1.850737777,-1.991886702,-3.2458085710000004,-0.052833064000000006,-0.04611805099999999,-0.249803733,-0.064322646,-1.624536319,-1.595513718,-1.798652774,-1.902822779,-1.761212169,-2.222561235,-3.18074925,-3.310867892,-0.099821273,-1.0266550840000002,-9.939668703999999,-10.15204019,-9.894594437,-9.855421227,-10.04061165,-9.755676017999999,-9.055072442,-11.57519656,-1448.1422777695116 -1983,1983,S128K,-0.112531175,-1.769479075,-2.201264704,-2.024671756,-2.380653616,-0.069100745,-0.069917138,-0.155145211,-0.302770657,-1.773036628,-1.7659215209999999,-1.9313588169999998,-2.471170591,-1.939675702,-2.109667809,-2.48415152,-2.277155712,-0.146076705,-1.13638157,-9.968428607,-10.10179744,-9.99029126,-9.926438393,-10.05288853,-9.770727417,-9.055072442,-11.57519656,-1460.313246281119 -1984,1984,S128M,-0.198782875,-1.511314354,-2.049144439,-2.088233373,-2.7541096119999997,-0.010537798999999999,-0.068827006,-0.32873874399999997,0.077440584,-1.5494947209999999,-1.473133986,-2.054604395,-2.0436844819999997,-2.01716379,-2.159302955,-2.9595796169999997,-2.5486396069999997,-0.419966313,-0.9698272640000001,-9.94414164,-10.13962422,-9.847012901,-9.833991989,-10.12719598,-9.772883102,-9.055072442,-11.57519656,-1459.0078056098428 -1985,1985,S128L,-0.184526395,-1.505193686,-1.8772706380000002,-2.309419662,-3.014886525,0.066557233,-0.077642374,-0.291410416,0.014258993999999999,-1.6087703690000001,-1.4016170019999998,-2.0547585919999998,-1.699782684,-1.90034818,-2.7184911439999997,-3.046883989,-2.98288906,-0.23280520600000001,-1.010719535,-9.981570526,-10.31303664,-9.966659691,-9.867466385,-10.06143769,-9.69925222,-9.055072442,-11.57519656,-1456.4596475767903 -1986,1986,S128N,-0.081474372,-1.548084941,-1.979870571,-2.002247627,-2.858229487,-0.090487505,-0.039080575,-0.123868169,0.082724532,-1.52626488,-1.5699050019999998,-1.9856170640000002,-1.974124077,-1.9147527030000002,-2.08974255,-2.63531978,-3.081139194,-0.20482735,-0.93529136,-7.36925621,-7.715035149,-7.47119458,-7.370648468,-7.002819092,-7.286583762999999,-6.928677437999999,-6.962839144,-1446.7705174204893 -1987,1987,S128Q,-0.102006272,-1.870261559,-1.864516557,-2.548003261,-2.952440127,-0.04512367900000001,-0.009388637,-0.19462390699999998,-0.06795693,-1.8414638319999999,-1.899059286,-1.969822797,-1.7592103159999999,-2.376079691,-2.71992683,-2.795616772,-3.109263482,-0.37151992799999994,-1.097881519,-9.926672137,-10.12087891,-10.04599197,-9.686287682,-10.1490668,-9.63113533,-9.019885811,-11.193242300000001,-1451.0750827654265 -1988,1988,S128P,-0.039479091,-1.35787052,-1.96086749,-2.232399823,-3.027514885,0.023319289,-0.043320909000000005,-0.035637272000000005,-0.052150165,-1.369708446,-1.346032594,-2.007981179,-1.9137538,-2.192389323,-2.272410322,-2.9673140630000003,-3.0877157060000004,0.400492443,-0.828949044,-10.01514559,-10.14841965,-10.06400735,-9.807408492999999,-10.20840218,-9.847490257,-9.055072442,-11.57519656,-1458.7086524353363 -1989,1989,S128R,-0.12132531699999999,-1.509393283,-2.037273473,-2.214769528,-3.158797018,0.0028081290000000004,-0.052069072,-0.19058156199999998,-0.083004859,-1.574435654,-1.444350911,-2.1669991000000004,-1.907547846,-2.0181925659999997,-2.41134649,-2.562668384,-3.754925652,0.096084474,-1.004895278,-9.787155513,-9.869352928,-9.948300483999999,-9.655300156000001,-9.939381119,-9.523442879,-8.941397563999999,-10.52730727,-1454.7395854943898 -1990,1990,S128T,-0.068305479,-0.33444885,-1.458091985,-2.090616501,-2.4044379190000003,0.09943721900000001,-0.07572071400000001,-0.060890244,-0.021153703,-0.248630202,-0.42026749700000005,-1.49841133,-1.417772639,-2.0280531319999997,-2.15317987,-2.1871780690000002,-2.621697768,3.851672414,2.192045554,-7.460366035,-7.415571739,-7.518218642999999,-7.191391609,-7.696567062000001,-7.480081123,-7.55595057,-7.055243389,-1448.3417411479168 -1991,1991,S128W,-0.16198607,-1.6363222830000002,-2.13909395,-2.161471007,-2.804468501,0.058580402999999996,-0.045422903,-0.278549237,0.031782372999999996,-1.520071792,-1.752572774,-1.9172760690000001,-2.360911831,-2.022502968,-2.300439045,-2.442040049,-3.166896952,-0.068443512,-0.932007817,-10.05523192,-10.26997732,-10.09023405,-9.873014656,-10.24041226,-9.802521324,-9.055072442,-11.57519656,-1456.9576796367764 -1992,1992,S128V,-0.158187015,-1.438201099,-1.7194717309999998,-1.883499401,-2.9806117089999997,0.058885985999999994,-0.033843865,-0.282530165,-0.038957406,-1.477046857,-1.399355341,-1.70595012,-1.732993341,-1.9447159269999998,-1.822282875,-2.519154968,-3.4420684489999998,4.011122061,1.765720587,-9.925436668,-10.07316266,-10.002851199999998,-9.678073425,-10.110121000000001,-9.76297506,-9.055072442,-11.57519656,-1454.2315532721113 -1993,1993,S128Y,-0.178490725,-1.687942789,-2.397879669,-2.426373953,-3.014799212,0.009939689,-0.087555083,-0.269426367,-0.12231459300000001,-1.642998485,-1.7328870930000002,-2.1023506690000002,-2.693408668,-2.043720765,-2.809027141,-2.831234631,-3.198363793,-0.030194923999999998,-1.046942645,-10.06943672,-10.17239769,-10.11911286,-9.94016629,-10.20241505,-9.913091697999999,-9.055072442,-11.57519656,-1449.5471300762147 -1994,1994,D129A,-0.011829943999999998,-1.408450114,-2.601650206,-2.009108856,-2.712578003,0.055625159,-0.018910208,-0.00474968,-0.262690485,-1.591538649,-1.225361578,-2.363404775,-2.8398956369999997,-1.946800443,-2.071417269,-2.588533139,-2.836622867,0.17175854100000001,-1.122244889,-10.56151826,-11.8151782,-10.32455698,-10.95312377,-10.79195688,-8.922775459,-7.463094196,-6.754707786,-1436.0742369282525 -1995,1995,D129C,-0.0038404409999999996,-0.36594841200000006,-1.459399925,-1.84969456,-2.466085328,0.124836252,0.023317966000000002,-0.030998848,-0.305725117,-0.38622226200000004,-0.345674561,-1.5663283540000001,-1.352471495,-1.994822061,-1.7045670590000002,-2.365487985,-2.56668267,3.6823781789999996,1.927697999,-10.97343627,-12.81853464,-10.19605974,-13.16457985,-9.489097267,-9.198909843,-7.172606021,-5.776755163,-1446.3497753017582 -1996,1996,D129E,-0.024722137999999998,-0.437193203,-1.5673487019999999,-1.853781284,-2.5048827559999998,0.064984523,0.059846614000000006,-0.109290889,-0.17906249899999999,-0.373456915,-0.50092949,-1.43162978,-1.703067624,-1.693792065,-2.013770502,-2.054698152,-2.9550673589999996,3.870388548,2.327016199,-9.535917332,-10.44951384,-9.203647354,-9.52667952,-9.179198402,-9.320547546,-7.791659991,-7.043508257999999,-1454.8813986256719 -1997,1997,D129G,-0.058882459000000005,-1.1061146179999999,-1.8097246319999998,-2.14584953,-3.1503486730000003,0.088618121,-0.002582539,-0.115182378,-0.385874494,-1.086667358,-1.125561877,-1.830504761,-1.7889445030000002,-2.162088455,-2.1296106040000002,-2.5607831030000003,-3.7399142419999998,3.5481144560000004,1.3491802290000001,-11.2020103,-12.00496219,-10.60032019,-11.85802313,-12.23805478,-9.3086912,-7.6890379289999995,-5.965991002000001,-1432.9804256753996 -1998,1998,D129F,0.053410467999999996,-1.3992555219999998,-2.2390579440000002,-1.9581412390000001,-2.827106995,0.065587057,0.10134154699999999,0.005479389,-0.289550178,-1.3662185059999998,-1.4322925380000002,-2.480507313,-1.997608574,-1.90900102,-2.007281457,-2.881726935,-2.772487055,1.0295432820000001,-0.807698371,-14.74710385,-15.31029925,-13.58688738,-16.80798142,-15.44906331,-12.58128791,-9.671750758,-11.08690701,-1459.953890610952 -1999,1999,D129I,0.12195738199999999,-1.5106593990000001,-2.0427498440000003,-2.111318141,-2.718844525,0.087808753,0.09814143199999999,0.145773331,-0.093117024,-1.394646214,-1.6266725830000002,-1.990421081,-2.095078606,-2.117884793,-2.1047514880000002,-2.8687619580000003,-2.568927091,0.431829843,-0.842943867,-13.67906109,-15.27736082,-12.37789369,-14.26754964,-14.13182085,-12.34068046,-9.671750758,-11.08690701,-1457.2453038487583 -2000,2000,D129H,0.10976663099999999,-1.2483044970000001,-1.9771825440000002,-2.196265839,-2.914716598,0.0826177,0.103060645,0.116472616,-0.347542125,-1.4837961430000002,-1.0128128509999998,-2.297054954,-1.6573101330000002,-2.026578657,-2.36595302,-2.999304572,-2.8301286230000002,0.9703119729999999,-0.9260675979999999,-11.32043294,-12.82869043,-10.03161928,-12.63614774,-11.21814159,-9.887565689,-7.693112642999999,-6.096182002999999,-1456.2471744376235 -2001,2001,D129K,-0.079646051,-1.316888882,-2.209058979,-2.039066649,-2.79710803,0.092081506,-0.025925852000000003,-0.133366249,-0.358431467,-1.4623979980000001,-1.171379766,-2.079362164,-2.3387557930000002,-2.030734617,-2.04739868,-2.7816117819999997,-2.8126042780000002,3.347442364,0.8203826759999999,-12.89603935,-13.73127371,-12.82347176,-13.90686343,-12.62764559,-11.39094226,-8.729112257999999,-8.173907681000001,-1463.5957205812447 -2002,2002,D129M,-0.005799360999999999,-1.744514476,-2.228149914,-2.296718212,-2.515168971,0.100907186,0.037297117000000005,-0.048895839,-0.236978513,-2.205675426,-1.283353525,-2.1024802890000003,-2.353819539,-2.229944001,-2.3634924219999998,-2.503699912,-2.526638029,-0.098573958,-1.237680814,-13.76827873,-15.37322535,-12.93097838,-14.58922565,-14.17326154,-11.77470274,-9.671750758,-11.08690701,-1456.714154670015 -2003,2003,D129L,-0.023379842999999997,-1.3406553270000001,-1.904621968,-2.177875,-3.197355755,0.09824696599999999,0.019536401000000002,-0.06629608599999999,-0.309047968,-1.3872000580000001,-1.294110595,-1.9267520009999999,-1.8824919340000001,-2.024252489,-2.331497511,-2.996978405,-3.397733105,3.446687315,1.058825631,-14.00906497,-15.46476691,-13.12358035,-14.8103076,-14.30693511,-12.33973488,-9.671750758,-11.08690701,-1455.0951376361772 -2004,2004,D129N,0.052958175,-0.867696536,-1.8813856569999998,-2.012423323,-2.770464705,0.050656662000000005,0.020455176999999998,0.08546117199999999,-0.085430195,-0.876132274,-0.859260798,-1.891036449,-1.871734865,-2.143438897,-1.8814077480000002,-2.894316063,-2.646613346,2.9459409260000005,0.9121094340000001,-8.919320782,-8.771351852,-8.27338649,-9.257446547999999,-10.03939047,-8.255028549,-6.651229801,-5.264599277,-1443.0857716766186 -2005,2005,D129Q,0.038189192000000004,-1.385652814,-2.005788889,-2.3129178130000003,-2.9204441969999997,0.094676408,0.09512320699999999,-0.018744824,-0.410593871,-1.5539129790000001,-1.217392648,-2.103930356,-1.9076474209999998,-2.231394068,-2.394441558,-2.982271233,-2.858617161,1.044908728,-1.000397661,-13.91128219,-15.35845213,-13.10743671,-14.05901527,-14.96308458,-12.06842224,-9.632368373,-10.79873915,-1449.2597199366428 -2006,2006,D129P,0.017618805,-1.4610978369999998,-1.993188282,-2.333790601,-3.018767965,0.073897677,0.015432443999999998,0.019805165,-0.23109149899999998,-1.574481414,-1.347714259,-1.927218233,-2.05915833,-2.2977199930000003,-2.369861209,-2.80555911,-3.23197682,0.461090977,-1.0202539259999999,-13.65381118,-14.7681695,-12.80506709,-14.36339105,-14.11708393,-12.21534432,-9.608956381,-10.82145565,-1455.3474495040718 -2007,2007,D129S,0.011819596000000002,-0.61259896,-1.8424749040000001,-2.4110432,-3.129493959,0.06775876,0.018533021,0.00510617,-0.175096311,-0.616647374,-0.608550545,-2.035896471,-1.649053336,-1.987268923,-2.834817477,-2.959994838,-3.29899308,1.56681955,-0.082826669,-10.57576444,-11.77745882,-10.99855804,-9.922616646,-11.21231445,-8.967874245,-6.371061183999999,-3.128094537,-1434.9869521886576 -2008,2008,D129R,0.028375638999999998,-1.43260327,-2.058856573,-2.12742487,-2.671514636,0.100741895,0.067515669,-0.010764392,-0.425023586,-1.539563953,-1.325642587,-1.9646425930000002,-2.153070553,-2.092106305,-2.162743435,-2.871012194,-2.472017078,3.614472057,1.029570397,-14.217889600000001,-15.762962599999998,-13.09037613,-15.42272258,-14.30651825,-12.50686844,-9.671750758,-11.08690701,-1460.9665830121376 -2009,2009,D129T,-0.015180192,-1.419740759,-1.994788519,-2.236750559,-2.844276943,0.077110372,0.000484728,-0.030845112,-0.341232651,-1.7009944609999998,-1.138487057,-1.9847439480000002,-2.004833089,-2.061055137,-2.41244598,-2.510902307,-3.1776515780000003,3.8457341210000004,1.195650811,-13.54016954,-15.12629653,-13.28578957,-13.69442089,-13.87408803,-11.720252699999998,-9.418473075,-9.658783954,-1439.6633597454056 -2010,2010,D129W,-0.052357805,-1.337561941,-2.0680788430000003,-2.7387071310000004,-2.957157889,0.071735078,0.012185782,-0.11690139199999999,-0.355725574,-1.339991598,-1.3351322829999999,-2.08958133,-2.046576355,-2.819105033,-2.658309229,-3.0928609430000003,-2.821454835,1.532020746,-0.61031982,-14.21796215,-15.16858621,-12.8766331,-15.66458355,-14.89324905,-12.48675885,-9.671750758,-11.08690701,-1462.2106177061796 -2011,2011,D129V,0.013005406,-1.4261294340000001,-1.782516038,-2.0350727280000003,-2.793114109,0.09568984900000001,0.037791967,-0.011781155,-0.30952918,-1.625361775,-1.226897093,-1.7825787830000002,-1.7824532919999998,-2.27801928,-1.792126175,-2.3756839309999997,-3.210544286,0.718500721,-1.028588993,-13.23629935,-15.05665861,-11.9137488,-13.66788264,-13.89113586,-11.65207081,-9.671750758,-11.08690701,-1450.0193615332246 -2012,2012,D129Y,-0.004803197,-1.808920774,-1.807537824,-2.060094514,-2.8181358960000003,0.066177267,0.052046555,-0.061652948,-0.600340011,-1.744944588,-1.872896959,-1.5748026609999999,-2.0402729859999997,-2.246334417,-1.87385461,-2.821120324,-2.8151514669999997,3.694833543,0.988652786,-15.01357392,-16.01895072,-14.24526814,-16.98064385,-15.313285,-12.50972189,-9.567958051,-10.36663755,-1458.021914652083 -2013,2013,N130A,0.009842616,0.020782053999999998,-0.395557714,-1.8189424509999998,-2.656971339,-0.093669078,-0.053254894000000004,0.072940125,-0.067322639,0.021797802999999998,0.019766305,-0.35209011700000004,-0.43902531,-1.8235589490000002,-1.8143259530000002,-2.6294382730000003,-2.6845044039999997,1.467109165,0.751625439,-12.98354641,-12.19228654,-11.38029607,-14.21973334,-13.31074714,-13.81466898,-9.806692222,-9.203411388,-1462.9205696922727 -2014,2014,N130C,0.024398517,0.109672713,-0.050340777,-0.02844622,-1.7461178609999999,-0.0035371459999999997,0.004808529000000001,0.043988505,0.053981812000000004,0.143180268,0.076165157,-0.039203664,-0.06147789,0.007428542,-0.064320981,-1.7698773019999998,-1.722358419,0.753028571,1.310198095,-12.80348507,-12.10647131,-11.436971400000001,-13.71755447,-13.38781839,-13.36860976,-10.20320526,-11.01779993,-1462.55907332059 -2015,2015,N130E,0.075540251,-0.506865954,-1.962355764,-2.385359875,-2.9601839560000003,-0.013509055,-0.08914534199999999,0.240225844,-0.030693744,-0.40078998200000004,-0.612941926,-1.87104568,-2.053665847,-2.176943011,-2.593776739,-2.890068282,-3.030299629,1.333622985,-0.018033341,-11.29058329,-10.4095993,-10.46944112,-11.5241302,-12.29480589,-11.75493994,-9.128649847,-7.5386653720000005,-1449.7599730375223 -2016,2016,N130D,-0.041373187,0.031127541,-0.063908363,-1.266128135,-1.95476231,-0.080367095,-0.074078273,-0.008668101,-0.0641175,0.017088067,0.045167015,-0.036439556,-0.09137716900000001,-0.9085584529999999,-1.623697816,-1.7871560069999999,-2.122368613,2.355137864,1.728763865,-9.102836044,-7.944507446,-8.510061836,-9.471690636,-10.27161156,-9.316308746,-8.196794015,-6.134887279,-1444.3965904111974 -2017,2017,N130G,-0.024233236000000002,0.04455197599999999,-0.039669193,-0.46562501,-2.413504986,-0.034404377,-0.05670689,0.008240418000000001,0.134250154,0.077153023,0.011950928000000001,-0.007814877,-0.071523508,-0.374706661,-0.556543358,-2.247677999,-2.579331972,1.423129076,1.3201015520000001,-9.600162699999998,-9.148767822,-7.414082024,-9.750855117999999,-11.36770308,-10.31940546,-6.361967029,-3.478570945,-1457.6576311271638 -2018,2018,N130F,-0.044510355,-1.682379431,-1.874811332,-2.18077384,-2.968582287,-0.056659869,-0.050862265,-0.038158444,-0.170572831,-2.017103653,-1.3476552080000002,-1.8330758280000001,-1.916546836,-2.205919948,-2.1556277319999997,-2.74295396,-3.194210613,-0.059893058,-1.16293563,-13.17195755,-12.61592044,-12.67158208,-13.22929736,-13.4082211,-13.93476675,-10.20320526,-11.01779993,-1453.9828378856182 -2019,2019,N130I,-0.06532156900000001,-1.25755066,-1.725859997,-1.97277285,-3.032615318,-0.012702834,-0.06922955900000001,-0.061413577999999996,0.36269863700000005,-1.258223287,-1.256878032,-1.6928971240000001,-1.75882287,-1.880695143,-2.064850556,-2.961797199,-3.103433437,3.295135625,1.283762523,-13.05782475,-12.07880782,-13.04095367,-14.51217242,-12.72139012,-12.93579974,-9.972288303,-9.640872774,-1457.2439876245335 -2020,2020,N130H,0.033708557,-0.845477885,-1.72417433,-2.021344251,-3.198228322,-0.032492802,-0.000551363,0.067968477,0.18607548,-0.8913066629999999,-0.799649107,-1.7722470609999998,-1.676101598,-1.864264572,-2.178423929,-3.1794498339999997,-3.21700681,3.108949663,1.190642147,-9.825878551,-9.0770121,-10.37934066,-9.991969894,-10.537751400000001,-9.143318703,-8.891296147,-7.847138651,-1459.3411666355096 -2021,2021,N130K,0.043483192000000004,-1.357394064,-1.8949240059999999,-1.977307498,-2.376040319,-0.014983327,-0.086058395,0.173024779,0.288065018,-1.2632209779999999,-1.45156715,-1.4014124469999998,-2.388435564,-1.80421979,-2.150395205,-2.466192539,-2.285888099,3.94734505,2.100943203,-9.518858356,-9.123144684,-9.033809555,-9.057015305,-10.32828936,-10.05203288,-8.619667813,-7.34346731,-1467.2642479795031 -2022,2022,N130M,-0.046735915,-0.282326592,-1.5084988030000002,-2.240817461,-2.9265659160000004,-0.025133531,-0.056008922,-0.037462907999999996,0.191155005,-0.196990649,-0.367662535,-1.5893565319999998,-1.427641074,-2.061585285,-2.420049636,-2.69552931,-3.157602522,2.6016566290000003,0.9724679740000001,-13.26129156,-12.0830046,-12.23582504,-15.28310062,-13.05174718,-13.65278037,-10.20320526,-11.01779993,-1462.7175333816558 -2023,2023,N130L,-0.061197303,-0.145357151,-1.6567672830000002,-2.3110628159999997,-3.026300201,-0.011388816999999999,-0.077565649,-0.044828955999999996,0.032792512999999995,-0.06443344299999999,-0.226280858,-1.58869992,-1.724834646,-2.135331344,-2.486794288,-2.58521518,-3.467385222,0.672870245,0.016609234,-13.31213448,-12.38581644,-12.38808017,-15.52882551,-12.91444947,-13.34350081,-10.20320526,-11.01779993,-1451.4358830396086 -2024,2024,N130Q,0.080382455,0.067851833,-0.03985369,-1.45297514,-2.8405697639999996,-0.09346985199999999,-0.024992275,0.185757185,0.09773332,0.087780114,0.047923552,0.017892537,-0.097599917,-1.274069015,-1.631881265,-3.089856628,-2.5912829,0.609229399,0.7150416940000001,-10.82362021,-10.06617358,-10.42454898,-11.36405898,-11.09258118,-11.17073836,-8.921545175,-7.475800759,-1454.6272732862271 -2025,2025,N130P,-0.00103399,-0.855582924,-1.8027762859999998,-2.130373139,-3.224951491,0.037335375,-0.072071789,0.07000381,0.10827761400000001,-0.8486937109999999,-0.862472136,-1.787728617,-1.817823955,-2.01820485,-2.242541428,-2.770838663,-3.679064318,3.209742597,1.256410713,-13.48429045,-12.61478319,-12.27783862,-14.80128957,-13.78832182,-13.93921903,-10.14242229,-10.76554452,-1461.0195148070343 -2026,2026,N130S,0.021364942,0.074347767,0.00060289,-0.021363454,-1.617914446,-0.09920153599999999,-0.013080459,0.055810343,-0.022724814,0.06712971400000001,0.08156582,0.020918333,-0.019712553,0.013989796,-0.056716703,-1.725102996,-1.510725895,0.6955947809999999,1.310974656,-7.483133296,-7.113253471,-4.955581055,-8.85895166,-8.425829193,-8.062051102,-6.931667112,-4.081639419,-1463.2038653404452 -2027,2027,N130R,-0.036261699999999994,-1.257133593,-1.883533601,-1.9680556980000001,-3.191577633,-0.065587718,-0.060221240999999995,-0.012302158999999998,0.034459672999999996,-1.3251700770000001,-1.189097109,-1.725081808,-2.041985394,-1.947641933,-1.9884694619999999,-2.727713993,-3.655441273,3.8660255169999997,1.7222579059999998,-10.32228416,-9.107186667999999,-11.10508169,-10.31290812,-10.64531119,-10.44093311,-8.479675992999999,-7.487590025,-1455.5819383319467 -2028,2028,N130T,-0.05860724900000001,0.017226658,-0.697481475,-1.7778530959999999,-3.1448427889999997,-0.00885697,-0.067965277,-0.049249220999999996,0.15729673800000002,0.043250172999999996,-0.008796857,-0.717848879,-0.677114071,-1.637705424,-1.9180007680000002,-2.731041937,-3.55864364,2.07927183,1.022977183,-9.676923064,-8.969382713,-7.329405746,-11.31274644,-10.03719245,-10.73588797,-8.251362366,-6.640448038,-1451.4595555081032 -2029,2029,N130W,-0.024835813999999998,-1.3103437390000001,-1.855493663,-2.150861522,-3.060188993,-0.06368613,-0.059137922999999995,0.009466295999999999,0.183329668,-1.261665534,-1.3590219430000001,-1.636945719,-2.0740416059999998,-2.310819835,-1.9909032080000002,-2.8478538469999997,-3.272524138,3.0423158960000003,0.9658634290000001,-13.1561764,-12.37614291,-12.82886566,-13.91650491,-13.46400338,-13.19536515,-10.20320526,-11.01779993,-1458.3451159247197 -2030,2030,N130V,-0.017208553,-0.513993003,-1.647175244,-2.0199940830000003,-2.6511703030000002,-0.019462686,-0.031363065,-0.00305404,-0.012964976999999999,-0.526614871,-0.501371134,-1.617706361,-1.6766441269999999,-2.078505652,-1.961482514,-2.682486453,-2.619854153,2.9582135689999998,1.173828442,-13.47061243,-12.36999066,-13.30877235,-14.88097434,-13.15816711,-13.63515768,-10.20320526,-11.01779993,-1453.919817775488 -2031,2031,N130Y,-0.058959356,-1.4263187259999999,-1.6778002840000001,-1.942094189,-2.880417633,-0.001114889,-0.02817506,-0.089743651,-0.11495451599999999,-1.527669449,-1.324968003,-1.5866796719999998,-1.768920895,-1.927339109,-1.956849268,-2.5893118569999998,-3.1715234089999997,4.114951448,1.902815074,-12.583025099999999,-11.84163783,-12.72054424,-12.38801036,-13.37711244,-12.58782061,-9.485482959,-8.173117226,-1452.5238595576957 -2032,2032,T131A,0.048297398,0.004449922,0.02299577,-0.029260658,-0.057694497000000004,-0.012444213,0.04212975099999999,0.054465044000000004,-0.056604423,-0.071647707,0.080547551,-0.035675032999999995,0.08166657299999999,-0.065340446,0.006819131,-0.080458732,-0.034930261000000004,1.514398944,2.4542898999999996,-4.246565831,-6.6098541410000005,-2.666873261,-4.6183227460000005,-4.677796371,-2.659982636,-5.073301823,-1.70212163,-1448.8774529397488 -2033,2033,T131C,0.013286748999999999,-0.008771147,0.012372812,0.01915539,-0.28010519300000003,0.070015408,-0.0006570139999999999,0.027230511000000002,0.051342263,-0.026297281000000002,0.008754986999999999,-0.028427311,0.053172934000000005,0.009204986,0.029105792999999998,-0.233781008,-0.326429378,1.159418384,1.867914336,-8.927557831,-10.38276093,-8.135883308,-8.573146202,-9.710283585,-7.835715126,-7.96272109,-4.885169463,-1456.0054847658612 -2034,2034,T131E,0.014478833,0.04320562,-0.68795339,-2.074980318,-2.26700351,-0.02890722,0.043174524000000006,-0.014216858999999998,-0.012240498999999998,-0.039854104,0.126265343,-0.337759154,-1.038147626,-1.152091357,-2.9978692789999997,-1.7959030480000002,-2.738103971,3.10804231,2.2674934230000003,-10.92003821,-11.98953738,-9.782994125,-12.53009324,-11.31500587,-8.982560417,-8.066085602000001,-4.236736375,-1445.41395712737 -2035,2035,T131D,-0.094024934,-0.35089954700000003,-1.191625028,-1.8809662169999999,-2.363424755,0.06999575799999999,-0.051876448,-0.136173419,-0.137672152,-0.14479698800000002,-0.557002106,-1.236823776,-1.14642628,-1.795152953,-1.9667794809999999,-1.71880534,-3.0080441689999997,4.089583049,2.678782411,-11.69234144,-14.42583477,-11.90158421,-14.36455279,-10.79145442,-6.978280998,-8.54861227,-5.05816539,-1447.6167201208882 -2036,2036,T131G,0.047606494000000006,0.013551701000000001,0.012045051000000001,0.03017478,-0.0515058,-0.024579447999999997,0.042201062000000004,0.053011925,4.09e-05,-0.062548746,0.089652148,-0.02412637,0.048216472,0.012509791000000001,0.047839768,-0.064465288,-0.038546311,1.461429717,2.542843565,-7.088991402,-8.60154879,-4.817755928,-8.218120277,-8.63810849,-5.169423523,-6.01476389,-3.3945295339999997,-1449.4239046894945 -2037,2037,T131F,0.0014948589999999999,0.052081815,0.04874863,-0.095103385,-1.8673641769999998,0.060898747,0.014406205,-0.011416488,0.10455611,-0.047708494000000004,0.151872124,-0.017418749,0.11491600800000001,0.021557932999999998,-0.211764702,-1.442284844,-2.292443509,0.81676416,1.333682387,-10.59671192,-13.56747997,-9.515429122999999,-10.23048791,-12.20748679,-7.462675827000001,-7.770374587999999,-4.868697549,-1456.0377722149715 -2038,2038,T131I,0.002171054,-0.122951715,-1.20479453,-2.222924378,-2.899965958,-0.022934467000000004,0.048435571,-0.044093464000000006,0.02428686,-0.082489638,-0.163413792,-1.013969286,-1.395619774,-1.952979466,-2.49286929,-2.5668279330000003,-3.233103983,2.619610036,1.224999762,-9.405303828,-10.57299089,-8.578396675,-9.376633803999999,-11.77050418,-6.727993591000001,-7.51698672,-3.431465041,-1448.9878636589274 -2039,2039,T131H,0.028226936,0.02463272,0.058249780999999994,-1.14772423,-1.881907864,0.02076724,0.058959530999999996,-0.00250566,0.001041058,0.011361658,0.037903782000000004,0.022919771000000002,0.093579791,-1.0059000820000001,-1.2895483779999999,-2.306129426,-1.457686302,1.9801443930000002,1.328163266,-12.43942887,-16.253795,-10.80072688,-12.38720581,-12.06989527,-10.68552142,-9.067932449,-5.568424604,-1456.6599575961009 -2040,2040,T131K,-0.058575127000000005,-0.028344682000000003,-1.106862664,-1.834230874,-2.769964672,0.04038543,-0.06423854400000001,-0.05291171,-0.047411891,-0.08216411900000001,0.025474756,-0.92262283,-1.291102497,-1.8152229359999998,-1.8532388119999998,-2.265214601,-3.274714742,3.302068293,1.9418659569999999,-13.56810852,-14.729556500000001,-14.68345431,-13.33579398,-13.23829883,-11.85343899,-10.32832796,-7.642594571,-1453.688775712857 -2041,2041,T131M,0.021392737000000002,0.066812967,0.063199091,-0.015479573,-2.2853065790000002,0.001275874,0.053564499,-0.010779025,0.012610228000000001,0.031158667,0.10246726699999999,0.049264407,0.077133774,0.073005109,-0.103964255,-1.7378552530000002,-2.8327579039999997,0.6190730179999999,1.306643808,-9.861472601000001,-12.29019492,-8.348089005,-9.240649178,-11.69247783,-7.73595208,-8.220714059,-4.712211831,-1455.5620489344 -2042,2042,T131L,0.022006502,0.034902455,0.035972631,0.04639541,-1.456442477,0.042640594000000004,0.018568335,0.025444667999999997,-0.02323047,-0.033005957,0.102810866,-0.007412929,0.079358191,0.06070085,0.03208997,-1.392526659,-1.520358294,0.650505043,1.32569687,-8.174373665,-10.80712489,-6.380018967000001,-6.944152206,-10.76862739,-5.9719448779999995,-6.86075613,-2.594168944,-1457.9512561867014 -2043,2043,T131N,0.052592318,0.081785523,0.06686613,-1.2196547229999999,-2.0954179969999998,0.01203924,0.049016871,0.056167765,-0.02008759,-0.061074337,0.224645383,-0.051201870999999996,0.18493413,-1.206410527,-1.2328989190000001,-1.938948782,-2.2518872119999997,2.661051326,1.8435594119999998,-10.06126338,-13.27005539,-9.455758162999999,-12.503653199999999,-8.562573181,-6.514276962,-8.906852995,-2.284009593,-1445.2640237316955 -2044,2044,T131Q,0.052493263,0.065880434,-0.20387656899999998,-1.434802519,-3.027916002,-0.021407805,0.093950274,0.011036252,0.00503871,0.00893029,0.122830577,-0.140835973,-0.266917165,-1.320855732,-1.548749305,-2.8530341530000003,-3.20279785,1.076757593,0.7619866829999999,-12.04628926,-13.36329772,-10.75826996,-13.00881847,-12.42807006,-10.67299008,-9.025999967999999,-5.538630082999999,-1448.7571078939363 -2045,2045,T131P,-0.002501147,0.017751106000000003,-0.067160285,-1.437859926,-2.281962266,0.030246559,0.025453949,-0.030456242999999997,-0.032146624,-0.02667684,0.062179051,-0.025140923,-0.10917964599999999,-1.320431939,-1.5552879130000001,-2.31841307,-2.245511462,0.434296412,0.701866598,-7.53475773,-9.945623276000001,-5.960029106,-7.604709053,-9.026103187999999,-5.137324028,-7.20415787,-3.51864778,-1442.5017700009048 -2046,2046,T131S,0.046852555,0.032947322,0.07451319099999999,0.031751946,-0.001675894,-0.038013249,0.046399272000000005,0.047305837,0.028249964,-0.03163583,0.097530474,0.043441285999999996,0.10558509599999999,0.004992831,0.05851106,0.000939062,-0.004290849,1.248566977,2.72936441,-3.821205298,-4.472364311000001,-3.18822287,-4.050491608,-4.644079247,-2.750868454,-4.463425473,-2.522269712,-1450.778109156061 -2047,2047,T131R,0.050172972999999996,0.039187439,-1.13788643,-1.812974307,-2.1567568969999997,0.005204788,0.06707830099999999,0.033267644,-0.038858987000000005,-0.02052667,0.098901548,-0.9822600570000001,-1.293512803,-1.559894389,-2.066054225,-2.1245248340000003,-2.188988959,3.628021564,2.358921315,-12.75870828,-14.96183696,-10.28337519,-13.48510148,-12.98279372,-12.08043405,-9.342256839,-5.9166558810000005,-1456.2482854814734 -2048,2048,T131W,0.021055777,-0.002815329,-0.085255308,-1.4243991569999999,-2.299041508,0.01387109,0.040213791,0.001897762,-0.003721882,-0.061463957,0.055833299,-0.055846379,-0.11466423699999999,-1.303434223,-1.545364091,-2.0383263830000002,-2.559756632,2.581354826,1.712923916,-12.75646131,-15.22410963,-11.18275576,-12.99697552,-13.64308494,-10.73538071,-9.800797657,-6.314157085,-1463.8444938170724 -2049,2049,T131V,0.007907616,0.038888167,0.08239005099999999,0.069681459,-1.578518336,0.007673937,0.016066771,-0.00025154,-0.033384935,0.01560534,0.062170994,0.05916744400000001,0.10561265800000001,0.123954756,0.015408161,-1.529645828,-1.627390844,0.13042873800000002,1.299862708,-6.790883974,-8.165201324,-5.51369799,-6.767639915,-9.373176628,-4.13470401,-5.90168151,-2.6747125819999997,-1449.195327276364 -2050,2050,T131Y,0.11888805599999999,0.057136108,0.052911575999999995,-0.6959789740000001,-1.8470273240000001,-0.005336982,0.12290350300000001,0.114872608,-0.00513964,-0.073755368,0.188027584,-0.065046197,0.17086934899999998,-0.34613763700000005,-1.04582031,-1.808615013,-1.8854396340000001,1.520045735,1.3883950569999999,-11.48385724,-15.21080721,-10.45551006,-11.23754785,-11.73262743,-8.782793677999999,-8.30285788,-4.266752662,-1460.1090237451717 -2051,2051,A132C,-0.006064091,0.029966262999999996,-0.501014401,-1.437874555,-2.939642149,0.018458061,0.025583765,-0.037711947,0.012604995,0.097407365,-0.03747484,-0.237032501,-0.7649963009999999,-1.41100089,-1.464748219,-2.736940785,-3.142343512,1.327313557,0.8034763559999999,-5.853107501,-6.582799026,-3.7893286510000004,-5.651686347999999,-8.773572342000001,-4.4681511380000005,-5.49571702,-4.022096908,-1462.1889153174125 -2052,2052,A132E,0.114228499,-1.43646584,-1.591899839,-1.785240095,-2.062191363,0.03875047,0.147340431,0.081116567,-0.00365282,-1.673624145,-1.199307535,-1.7086104030000002,-1.475189275,-1.9468196880000002,-1.623660501,-2.545760855,-1.578621871,-0.04555221,-1.003656415,-10.51240111,-10.21643024,-10.50315656,-10.11584777,-11.10218322,-10.62438775,-9.72973559,-10.89818902,-1458.9387809499167 -2053,2053,A132D,0.123345169,-1.4248093169999998,-1.939286464,-2.453659296,-2.770201187,0.03346145,0.18536128899999998,0.061329048,-0.077310373,-1.607088424,-1.24253021,-1.943104678,-1.93546825,-2.005222705,-2.9020958869999998,-2.604163871,-2.936238503,-0.037436219,-1.024809728,-10.84490336,-10.55430067,-10.95464105,-10.59341626,-11.3753049,-10.74685392,-9.72973559,-10.89818902,-1456.1333727487363 -2054,2054,A132G,0.012875998,0.032919828,0.029576208,-0.9510449320000001,-1.8247725430000001,0.029134626,0.025100992000000003,0.000651003,-0.0017208070000000002,0.07946679799999999,-0.013627142,0.017328293999999998,0.041824122000000005,-0.477978561,-1.4241113019999998,-2.046956504,-1.602588581,1.65032148,1.369195617,-4.981527443,-3.399084785,-6.03902446,-4.401973328,-4.556239304,-6.511315337999999,-4.8129852810000004,-2.992713268,-1462.0409769085236 -2055,2055,A132F,0.032811053,-1.449931937,-2.065231766,-2.556725852,-2.8732677439999996,-0.043875388,0.06911534400000001,-0.003493238,-0.025723338999999998,-1.530773819,-1.369090055,-1.8667900730000002,-2.263673459,-2.104999358,-3.0084523460000003,-2.703940525,-3.042594962,0.10320787,-0.95203174,-10.66905999,-11.04531861,-9.018539787,-10.73556838,-12.81246387,-9.733409279,-8.428305965,-8.117334739,-1462.0779364737682 -2056,2056,A132I,0.009760616,-1.70974813,-2.475562956,-2.42746642,-2.806477679,0.01298041,-0.032247231,0.051768462,-0.085366657,-1.658560398,-1.7609358609999999,-2.295606648,-2.655519264,-2.232785938,-2.622146901,-2.655635845,-2.9573195130000003,-0.145854076,-1.065521983,-10.03374351,-10.26466418,-9.488431534,-9.169355644,-11.26150651,-9.984759659,-8.048737693,-6.609464196,-1462.7797750565223 -2057,2057,A132H,0.116313931,-1.527950804,-2.021731608,-2.274665067,-2.352646332,0.111492013,0.117537473,0.115090388,-0.068841968,-1.26062039,-1.7952812180000002,-1.897666639,-2.145796576,-2.135875925,-2.413454209,-2.257695837,-2.447596826,3.835529539,1.616839589,-10.71533692,-11.01394444,-9.824030365,-10.2113696,-11.74507465,-10.78226556,-9.72973559,-10.89818902,-1466.9367714519612 -2058,2058,A132K,0.040213241000000004,-1.671123709,-1.863874517,-2.744444229,-2.8224254930000003,0.11316524,0.06835418,0.012072301,-0.096010872,-1.7313075340000001,-1.6109398830000001,-2.067323788,-1.660425246,-2.606563069,-2.8823253889999996,-2.728382981,-2.916468005,-0.214287717,-1.069204396,-11.04650336,-11.04853158,-10.58577379,-10.45940125,-11.89576771,-11.24304246,-9.72973559,-10.89818902,-1471.4637866127305 -2059,2059,A132M,0.09022340400000001,-1.296283006,-2.079955608,-2.293298444,-2.760355333,0.072039739,0.116418157,0.06402865,-0.077310373,-1.37011953,-1.222446481,-2.308195775,-1.8517154409999999,-1.76825381,-2.8183430780000003,-2.668224972,-2.852485694,0.378560797,-0.839550095,-11.13301672,-11.54976551,-10.7554671,-10.54537672,-12.78661772,-10.02785655,-9.248606446,-8.777925005,-1460.9479522197507 -2060,2060,A132L,0.037136439,-1.7554314819999999,-2.136470769,-2.222177353,-3.316870495,0.031193143,0.039675973999999996,0.034596904,-0.11489805800000001,-1.547910574,-1.96295239,-2.114375749,-2.158565789,-2.09731253,-2.347042175,-3.1733749510000004,-3.460366038,0.359371583,-0.956849455,-9.922089066,-10.14306073,-8.818730827000001,-9.282764191,-11.86145026,-9.504439316000001,-7.883132477999999,-5.875809567999999,-1460.2708445950411 -2061,2061,A132N,-0.035823613,-1.5423479,-2.124174334,-2.615668421,-2.693649685,0.011981297,-0.042590637,-0.029056589,-0.025303934,-1.629508601,-1.455187199,-1.965524855,-2.2828238130000003,-2.203734141,-3.0276027,-2.6265840480000002,-2.760715321,-0.288281379,-1.029582573,-11.12883051,-11.12199509,-10.98154572,-10.46085942,-11.81339555,-11.26635675,-9.72973559,-10.89818902,-1461.9064642214216 -2062,2062,A132Q,0.223275258,-1.464977241,-1.4447436830000002,-1.848192141,-2.31524903,-0.007387058,0.23699208800000002,0.209558427,-0.024547981,-1.445144816,-1.4848096659999999,-1.480131074,-1.4093562919999998,-2.195461615,-1.500922666,-2.317281527,-2.3132165330000003,3.6600276380000003,1.539543387,-10.88706402,-10.73500231,-10.37638845,-10.32904043,-11.78034626,-11.21454266,-9.72973559,-10.89818902,-1462.3635513917543 -2063,2063,A132P,0.054740122999999995,-1.359358557,-1.978764977,-2.232701428,-2.31679992,0.06392502,0.040229705,0.069250541,-0.09458081900000001,-1.304114373,-1.414602741,-2.127471047,-1.830058907,-2.131597127,-2.3338057290000003,-2.332598285,-2.301001555,0.63560276,-0.7651545679999999,-9.453728931,-8.831089066,-9.837172417,-9.266142143,-9.79164328,-9.542597748,-8.347959236,-7.434468637,-1451.3018894488923 -2064,2064,A132S,0.048387742000000004,0.031828906000000004,0.014568271,-0.006924016999999999,-1.153553251,0.000141085,0.062201562,0.034573921,-0.003773878,0.032633962999999995,0.031023849,0.009955158,0.019181384,0.01038225,-0.024230283999999998,-0.8304004340000001,-1.4767060669999998,0.57354371,1.350739897,-5.656036942999999,-5.2172524639999995,-5.80262352,-5.26595855,-6.557216553,-5.437133629,-6.0351906689999995,-4.007072365,-1448.9917973135598 -2065,2065,A132R,-0.031128682,-1.678372908,-2.015521486,-2.8732124530000003,-3.12458746,0.066831497,-0.034769594,-0.02748777,-0.070073994,-1.715699951,-1.641045865,-1.817632999,-2.213409973,-2.612144786,-3.13428012,-2.9558134469999997,-3.293361473,-0.020652138,-1.05255572,-10.77764605,-10.59519766,-10.41551293,-10.39286393,-11.30013215,-11.184523599999999,-9.478356107,-9.568577795,-1469.3065135157667 -2066,2066,A132T,-0.005427035,-0.006983294,-1.215919415,-1.6845347569999998,-2.174470391,0.019224322,0.017731886000000002,-0.028585956000000003,-0.035831681000000004,0.11881377800000001,-0.132780365,-1.22438106,-1.20745777,-1.580689658,-1.788379855,-2.128478302,-2.220462479,3.805997275,2.457253178,-6.68337422,-6.465436812999999,-6.510020493,-6.187431564,-7.202506812999999,-7.051475418,-6.301641336,-4.139465701000001,-1445.821024840232 -2067,2067,A132W,0.012252581,-1.5792686669999998,-1.9582124280000002,-3.022770532,-2.862191169,0.042107535999999994,0.038675114,-0.014169952,-0.06003002599999999,-1.4759171580000001,-1.682620175,-1.7741448519999998,-2.142280003,-2.790505387,-3.2550356760000003,-2.435204045,-3.289178292,0.5315922820000001,-1.0815985909999999,-11.44642563,-11.57371535,-10.68510567,-11.15671055,-12.74865271,-11.06794385,-9.72973559,-10.89818902,-1466.658357470762 -2068,2068,A132V,0.014852203000000001,-0.934913715,-1.5530998280000001,-1.875184636,-1.95815801,0.036240483,0.024177119,0.005527287,0.01766514,-0.770534158,-1.099293272,-1.7641277309999999,-1.342071924,-1.964548455,-1.785820816,-2.086368367,-1.829947653,4.363113437,2.4701415780000002,-8.552688213,-8.871125443,-8.242530334,-7.75441626,-9.585092171,-8.310276855,-7.929021317999999,-6.605900367,-1455.075461419765 -2069,2069,A132Y,0.040473425,-1.508546489,-2.377388556,-2.780837013,-2.8588182769999997,-0.0055845619999999995,0.079588475,0.0013583739999999999,-0.014423556,-1.528482022,-1.488610955,-2.040589535,-2.7141875769999997,-2.579828816,-2.98184521,-2.7016487280000003,-3.0159878260000004,-0.21230520000000003,-0.983991156,-11.538252900000002,-11.63020685,-10.21801668,-11.43909747,-13.44771854,-10.95622496,-9.72973559,-10.89818902,-1463.8025309653021 -2070,2070,A133C,-0.00774145,0.001291328,0.037568662,-0.003170465,-1.849881352,0.096780884,-0.007817289,-0.00766561,-0.01070332,-0.034425536,0.037008192,0.035726364,0.039410959,0.0536446,-0.05998553,-1.702430536,-1.997332167,0.578072086,1.308581815,-9.389295607000001,-10.07753066,-8.681223152000001,-9.953741989,-8.865463959,-9.368518272000001,-6.656134571,-1.6463722440000002,-1449.4853856842965 -2071,2071,A133E,-0.052919691,-1.26141188,-2.156214639,-2.164244365,-2.123472185,0.09342379,-0.057826017,-0.048013364,-0.055258882999999995,-1.2846287859999999,-1.238194974,-2.0464603919999997,-2.265968886,-1.8602519990000002,-2.46823673,-2.2617385469999998,-1.985205822,0.710260734,-0.731128344,-10.38900965,-10.70936898,-9.677686873999999,-11.33146502,-10.56433263,-9.66219474,-7.004870955,-5.546053054,-1463.9590600151569 -2072,2072,A133D,-0.060583051,-1.197046488,-1.793192469,-1.641223277,-1.5592061959999999,0.086565835,-0.049196497,-0.071969605,-0.029375917999999997,-1.125666853,-1.268426123,-1.66564971,-1.920735228,-1.490436701,-1.7920098530000002,-1.801746619,-1.316665773,4.555122368999999,2.718828357,-9.25564059,-11.70155454,-8.116262825,-9.58336055,-9.877907927999999,-6.999117104,-6.404737485,-4.729045598,-1466.3764256471768 -2073,2073,A133G,-0.020973722,0.019722893999999998,0.009274628,0.022143252000000002,-0.05375177,0.01095523,-0.044556730999999995,0.002609288,-0.043059914000000005,-0.05470645,0.09415223699999999,-0.0008277060000000001,0.019376962,0.0039499059999999996,0.040336597,-0.068984932,-0.038518607,1.38979435,2.429750622,-2.114148592,-2.90629068,-0.978243462,-2.0354526980000003,-2.8361305619999997,-1.8146255569999998,-2.057832576,-1.22210873,-1469.879375917837 -2074,2074,A133F,-0.063003197,-0.16112385099999998,-1.566228016,-2.287242107,-2.774922353,0.081603475,-0.026656091,-0.099350303,-0.08720464900000001,-0.017872849,-0.304374853,-1.273272562,-1.85918347,-1.910972909,-2.663511305,-2.789580712,-2.7602639939999998,2.527726898,1.081890835,-13.2825995,-13.01485751,-12.30837585,-15.19420873,-15.20173439,-10.69382101,-7.084619459,-4.132919461,-1449.4246077584103 -2075,2075,A133I,-0.177098339,-1.082032108,-1.902831071,-2.362405789,-2.810495412,0.016525928,-0.139012072,-0.215184605,-0.14774653599999998,-0.762590155,-1.40147406,-1.737029855,-2.068632286,-1.754941444,-2.9698701339999998,-2.554368001,-3.0666228230000003,4.03891515,2.154251558,-8.751213298,-7.486889832,-8.086217292999999,-9.537004341,-10.36031095,-8.285644073,-5.97459938,-4.9894596,-1445.6695546312258 -2076,2076,A133H,-0.043598824,-0.828241888,-2.190497255,-2.572620994,-2.631634991,0.028374381,-0.04745368,-0.039743968,0.003959035,-0.705576717,-0.950907059,-2.166378328,-2.214616182,-1.8832599209999998,-3.2619820660000003,-2.205565224,-3.0577047580000003,0.644202402,-0.5080581270000001,-12.08671349,-12.97476728,-11.02879521,-12.91909661,-12.404250099999999,-11.10665824,-6.687620064,-5.057104272,-1471.7952039334923 -2077,2077,A133K,-0.017349745,-1.32063772,-2.2426710180000002,-2.46368511,-2.2612597340000002,0.20475411899999998,0.072780021,-0.107479511,-0.058972827,-1.204733827,-1.4365416130000002,-2.010031127,-2.475310909,-2.249791466,-2.677578753,-2.3502480180000003,-2.17227145,0.5453004920000001,-0.7157640409999999,-13.19439943,-14.33375819,-11.14777094,-13.90210912,-13.46599479,-13.12236411,-9.504542946,-9.511394586,-1474.7435405123979 -2078,2078,A133M,0.028706852,-1.079755671,-2.4009662869999997,-2.621980379,-2.570070001,0.040153741,0.014876974,0.04253673,-0.158257748,-1.03953191,-1.119979431,-2.203851153,-2.598081421,-2.443611492,-2.800349265,-2.544068044,-2.596071958,1.042139125,-0.567285919,-9.771020815,-10.40731659,-7.9707571260000005,-11.66663051,-11.33992259,-7.470477257000001,-5.961816046,-3.2886428060000004,-1450.8864080617204 -2079,2079,A133L,-0.023771839,-1.438953689,-1.914494184,-2.408779607,-3.356869229,-0.001307246,-0.040304201,-0.007239476,-0.075257224,-1.53840066,-1.339506718,-1.885544545,-1.9434438219999999,-2.329424866,-2.488134347,-2.952760164,-3.7609782939999996,0.259806378,-0.936989631,-10.74899775,-9.383950073,-9.574002411,-12.77702496,-12.16264791,-9.847363396,-6.396691796,-4.166792226,-1444.8048379858956 -2080,2080,A133N,-0.033292747000000004,-0.112756883,-1.638780383,-2.58337349,-2.531463113,0.07096126900000001,-0.053428335,-0.013157159,-0.064517781,-0.158221697,-0.067292068,-1.32254094,-1.955019825,-2.407399319,-2.75934766,-2.507855872,-2.555070353,1.070058006,0.116851439,-9.605253931,-12.00489783,-7.957694388999999,-10.49814243,-8.553965309,-9.011569695,-6.204463429,-2.829194632,-1468.2516713608056 -2081,2081,A133Q,-0.023546229,-1.310598168,-2.390766448,-2.549311171,-2.948945787,0.057132710999999996,-0.002123469,-0.044968988,-0.146579722,-1.357595245,-1.263601091,-1.9198544969999998,-2.861678398,-2.034676099,-3.063946242,-2.737192643,-3.16069893,3.595524223,1.277128463,-10.702571800000001,-11.49320576,-9.437451096,-11.95676651,-11.02177103,-9.603664581,-6.449225778,-5.065392547,-1468.4865661347285 -2082,2082,A133P,-0.040955646,0.012284614,-0.882498583,-1.925318455,-2.451581678,0.056875402,-0.04850295599999999,-0.033408335,-0.024980272999999997,-0.080533337,0.10510256400000001,-0.494208593,-1.270788572,-1.768420162,-2.082216748,-2.481155871,-2.422007485,1.840730024,0.87914301,-11.33930482,-12.11989972,-10.01776789,-11.81966429,-12.75390804,-9.985284164,-8.210376834,-6.551920834,-1456.1628618529066 -2083,2083,A133S,-0.012720948999999999,-0.026892709,0.001395003,3.39e-05,-0.15775672400000001,0.010813072,-0.04888161,0.023439712999999997,-0.007852237,-0.09218310800000001,0.038397691,0.001109568,0.0016804379999999998,-0.036577086,0.03664495,-0.162017303,-0.153496145,1.349787602,2.118171785,-5.868307744,-7.650990752999999,-5.309726974,-4.762800125,-6.779021667,-4.838999199,-5.161482371,-1.7807722030000002,-1454.8662172304466 -2084,2084,A133R,-0.057304827999999995,-1.494103276,-2.121975064,-2.5040167209999997,-3.1528066139999997,0.098175297,-0.052174997,-0.062434658,-0.05081940099999999,-1.587892976,-1.4003135759999998,-1.902367744,-2.341582383,-2.1816366240000002,-2.826396817,-2.905342467,-3.4002707610000003,0.07455738099999999,-0.9866549920000001,-12.96936906,-13.85266205,-12.13774004,-14.21762111,-12.97143096,-11.66739115,-8.598798594,-7.209853282999999,-1467.3132112352178 -2085,2085,A133T,-0.052233510999999996,-0.029663601,-0.0336638,-0.051248148,-0.12496147199999999,0.24018693100000002,-0.077983089,-0.026483932999999998,-0.02073436,-0.087887381,0.02856018,-0.03839383,-0.02893377,-0.034589767,-0.067906528,-0.13252866300000002,-0.11739428,1.38511591,2.253642628,-5.790642127999999,-6.242858147000001,-4.903600319,-5.1318749310000005,-7.3317110670000005,-5.343166176,-4.099609931,-0.277679915,-1468.494494061917 -2086,2086,A133W,-0.039195892,-1.686324619,-2.166296844,-2.750810299,-2.815941524,0.060651124,-0.048767156,-0.029624627999999997,-0.204396868,-1.812635425,-1.560013813,-1.8239872080000001,-2.508606479,-2.489716279,-3.011904318,-3.0672940860000004,-2.5645889619999997,0.20075211899999998,-1.143334729,-14.05845078,-14.317036300000002,-12.42222981,-15.703980300000001,-15.26654169,-12.58246579,-8.158189584,-6.551920561,-1463.208665015176 -2087,2087,A133V,-0.06317093,9.08e-05,-0.718635949,-1.8157551980000002,-2.07968605,0.035907141000000004,-0.069466787,-0.056875072,-0.021419075,-0.038935517999999995,0.039117116,-0.362355132,-1.074916765,-1.51162056,-2.119889836,-2.059235143,-2.100136956,3.163755076,2.107755516,-6.042386852999999,-4.1772857210000005,-6.507542961,-6.505611946,-7.407618522999999,-5.613875114,-4.373040704,-3.5271899060000003,-1442.8488761261106 -2088,2088,A133Y,-0.02818377,-1.072351789,-1.965880954,-2.451031934,-3.001181548,0.023059045,-0.015989003999999998,-0.040378536,-0.066344536,-1.134889053,-1.009814525,-2.032940406,-1.898821501,-2.448792004,-2.4532718630000003,-2.8502785530000003,-3.152084542,0.359396107,-0.6622715020000001,-14.905617600000001,-14.50277558,-14.69903336,-16.30012209,-15.38673055,-13.63942642,-7.312161304,-5.653100571,-1457.540324345231 -2089,2089,N134A,-0.031905678,-0.052893833,-0.050714032,-2.100340961,-2.730906615,0.036228598,-0.011659487,-0.052151868,-0.008751383,-0.012415235,-0.09337243,-0.022693356,-0.078734707,-1.835683301,-2.36499862,-2.747694683,-2.714118547,0.709957921,0.676320108,-11.05552694,-10.63572585,-12.29716949,-10.86220663,-11.15836023,-10.32417251,-7.045983366000001,-5.832300094,-1443.0601922273636 -2090,2090,N134C,-0.01571925,-0.045847610999999996,-0.013444764,-1.331412761,-3.421395372,0.057415135,-0.039915606,0.008477106,-0.029403756,-0.032370357999999995,-0.059324863,-0.05451088,0.027621352000000002,-1.274212471,-1.38861305,-3.204973289,-3.637817454,0.8239929159999999,0.7354547440000001,-12.30950106,-11.46564835,-12.57027802,-12.25768144,-13.5550625,-11.69883501,-8.083416532000001,-6.714562242,-1451.461910417769 -2091,2091,N134E,-0.078295274,-0.053043466,-1.6542827409999998,-2.913611882,-2.9469093539999998,0.082622979,-0.044107680999999996,-0.112482866,0.00820283,0.041841473,-0.147928405,-1.459545705,-1.849019776,-2.230562745,-3.5966610180000003,-2.4561932509999997,-3.437625456,0.94902859,0.070063754,-10.9101593,-10.27388471,-11.96832476,-9.868750977000001,-11.75392719,-10.68590885,-6.393825785,-4.749996065,-1442.5283159697428 -2092,2092,N134D,-0.035669378,-0.051015135,-0.00905534,-0.255137305,-2.099289227,0.07213668200000001,0.0013324189999999998,-0.072671174,-0.086119805,-0.01091849,-0.09111178,-0.023083952999999997,0.004973273,-0.033893987,-0.47638062299999995,-1.8311545280000001,-2.367423925,0.786216963,1.308667843,-7.0461121460000005,-6.377023834,-6.372872887000001,-6.443305305,-7.84788195,-8.189476753,-4.720078186,-0.914599567,-1454.365530158393 -2093,2093,N134G,-0.042696060999999993,-0.009795514,-0.145007691,-2.095297776,-2.9425130580000003,0.06241614,-0.017741328,-0.067650793,-0.008849751,0.025510584,-0.04510161099999999,-0.06278225700000001,-0.22723312399999998,-1.920514221,-2.270081331,-2.790067165,-3.09495895,0.7416964079999999,0.667412464,-10.42146123,-9.592662025,-10.91589333,-10.94190007,-10.73856033,-9.918290398,-7.007411547,-5.203899748,-1444.1817263197154 -2094,2094,N134F,0.010498702,0.007487915,-0.344239229,-2.15392903,-3.1872265019999997,0.007743906,0.032978118,-0.011980713999999998,0.0061070000000000004,-0.010664201000000002,0.025640031,-0.234071887,-0.45440657100000004,-1.886780769,-2.42107729,-2.811381279,-3.563071724,1.213764948,0.701710031,-12.88434884,-11.06513589,-13.25898917,-11.94002518,-14.99677922,-13.16081474,-7.547883882000001,-5.87411083,-1458.3586786710657 -2095,2095,N134I,-0.046673060999999995,-0.009829494,-0.131542506,-2.3955424080000003,-2.8301996010000003,0.065328108,-0.01040813,-0.082937991,-0.019010722,-0.001396515,-0.018262473,-0.068053453,-0.195031559,-1.6731731490000001,-3.1179116660000004,-2.099463105,-3.5609360960000003,0.748306136,0.6931519559999999,-10.08582968,-8.239144936,-11.11518974,-9.893124352000001,-12.426028500000001,-8.755660857999999,-6.544382465,-4.675488579,-1453.6511188424192 -2096,2096,N134H,-0.029996631,-0.004613213,-2.95e-05,-1.9124516480000002,-2.534620405,0.042258175,-0.007796745999999999,-0.052196516,0.013857851000000001,0.016669241,-0.025895666,-0.004333887,0.004274863,-1.8219820230000001,-2.002921273,-2.131933414,-2.9373073960000005,0.668888598,0.6755676290000001,-11.07472223,-10.3318203,-11.68149506,-11.27882735,-12.45844143,-9.623027,-7.147283712999999,-5.096033422,-1456.1783865937032 -2097,2097,N134K,-0.033739776,0.01467132,-0.013498547,-2.214526153,-3.1263046,0.142865251,-0.010837392,-0.056642159000000004,0.015363206,0.00437672,0.024965919,-0.06228949599999999,0.035292402,-1.659630575,-2.76942173,-2.739133045,-3.513476155,0.812285027,0.698007114,-10.26030675,-9.642944069,-9.558576262999999,-10.47564099,-11.91747797,-9.706894447,-7.041619507,-5.491060002999999,-1452.414326646831 -2098,2098,N134M,-0.049266104000000005,-0.05664246,-0.130332789,-2.387290182,-2.975159889,0.051295742000000005,-0.021970349,-0.076561858,0.022073332999999997,-0.064668529,-0.04861639,-0.079771788,-0.18089379,-2.089349574,-2.685230789,-2.344943303,-3.605376474,0.689315232,0.64309882,-12.33233237,-10.55327546,-12.39575195,-12.6530474,-14.26567594,-11.79391107,-7.948603565,-6.7145622110000005,-1451.7542926240712 -2099,2099,N134L,-0.029542872,-0.018657668999999998,-1.534011065,-2.022538301,-2.8785001130000003,0.055225166,0.00324346,-0.062329204000000006,-0.043735357999999995,0.002171321,-0.039486658,-1.49123858,-1.576783549,-2.096480629,-1.948595972,-3.146019875,-2.610980351,0.23709827,0.01807044,-10.79479305,-9.172898636000001,-10.38800302,-11.51635293,-13.29052838,-9.606182297,-6.015359236,-3.270115207,-1448.9571429449134 -2100,2100,N134Q,-0.062254286,-0.022490201,-0.007066445,-1.6925473619999998,-3.0558708039999996,0.10440362,-0.046463643,-0.078044929,0.002472715,0.033018868,-0.07799926900000001,0.023879714,-0.038012603,-1.494933685,-1.890161039,-2.477526142,-3.634215465,0.644768291,0.702607311,-11.72171691,-11.41799112,-11.49758872,-11.50646503,-12.92059914,-11.26594056,-7.202670834,-5.874110754,-1449.8350156205706 -2101,2101,N134P,-0.044540223,-1.523915926,-1.9510901459999999,-2.612290159,-3.4871754999999998,0.042372859000000006,-0.040107091,-0.048973354000000004,-0.045100920999999995,-1.512840084,-1.534991767,-1.757867527,-2.144312764,-2.019007189,-3.205573129,-2.9278134319999998,-4.046537568,3.505642387,1.211322266,-14.45038301,-13.34624961,-15.19516088,-14.25503292,-15.90435201,-13.55111964,-9.637723922000001,-10.19675467,-1450.8642102316953 -2102,2102,N134S,-0.047201715,-0.016152634,-0.036010367,-1.87868483,-2.914040585,0.085059596,-0.021479542,-0.07292388799999999,-0.012722913,-0.015672712,-0.016632555,-0.06541710099999999,-0.006603632,-1.489961703,-2.267407956,-2.233042202,-3.595038967,0.901122658,0.7197793640000001,-10.732342,-9.959911346,-11.69039423,-11.01382729,-11.86434983,-9.13322728,-8.730166328,-7.771299106,-1442.722029583063 -2103,2103,N134R,-0.048921831,0.0030946640000000004,-0.01086617,-2.122802422,-3.074171492,0.09023775099999999,-0.039365822,-0.058477839000000004,-0.010479411999999999,0.030346911,-0.024157584,-0.023213246,0.001480907,-1.950470648,-2.295134195,-2.45594185,-3.692401134,0.56372064,0.6612275639999999,-12.85331412,-11.57918983,-14.37192673,-13.03938541,-13.69802308,-11.57804555,-6.98778989,-5.326581798,-1451.0929607460275 -2104,2104,N134T,-0.022748057000000002,-0.006699095,-0.009502881,-1.2409259990000001,-2.597705253,0.054396413,-0.011207449,-0.034288665,-0.028674185,0.007908243,-0.021306433,-0.027024659,0.008018896999999999,-1.003159122,-1.478692875,-2.222540679,-2.972869827,2.050725303,1.39093148,-8.73578004,-7.600750511,-9.12375045,-8.796739319,-10.2345674,-7.923092522,-7.088532999,-6.312017684,-1445.75107173156 -2105,2105,N134W,-0.044790109,-0.013371137,-1.453378166,-2.3085607280000002,-3.258416571,0.047954748,-0.022183973,-0.06739624400000001,0.004268285,-0.016559696000000002,-0.010182578000000001,-1.3896638430000001,-1.5170924890000002,-2.105715391,-2.511406064,-2.749489291,-3.767343851,2.358808048,0.8550511390000001,-14.8527196,-13.25204587,-15.27805738,-14.63193145,-16.7749931,-14.32657022,-9.637723922000001,-10.19675466,-1464.5487397003453 -2106,2106,N134V,-0.014140305,0.015117081000000001,-0.009214773,-1.76977729,-2.740153276,0.065345853,-0.002966844,-0.025313766,-0.004280686,0.023714027999999998,0.006520134,-0.012592373,-0.005837173,-1.6576609830000002,-1.881893597,-2.984318067,-2.495988485,0.64031039,0.688608157,-10.48935466,-8.875279915,-12.12948248,-10.45970982,-11.90717769,-9.07512339,-6.721214749,-5.540741262,-1447.598635490518 -2107,2107,N134Y,-0.036495177999999996,-0.015402827,-0.10655888300000001,-1.9590956080000002,-2.998510307,0.043191537,-0.018225627,-0.054764729000000005,0.009372842,0.021653277999999998,-0.052458932,0.029380627000000003,-0.24249839199999998,-1.8319939619999999,-2.086197253,-2.388617686,-3.6084029280000003,0.565377374,0.674038577,-13.30681882,-12.53292814,-13.82758156,-12.06288181,-14.61598795,-13.49471465,-7.640701506,-4.912788031,-1455.0558497859165 -2108,2108,L135A,-0.02112953,0.010085161,0.005087024,0.024460949,-1.73120652,0.032501255,-0.009176700999999999,-0.033082358,-0.04772345,-0.011639958999999998,0.031810281,0.010965899999999999,-0.000791853,0.043982252,0.004939646,-1.5871025069999998,-1.8753105330000002,0.7485259120000001,1.3197165309999999,-7.2134899279999996,-7.591431007000001,-9.282946922,-5.359962395,-7.711955337999999,-6.121153976,-5.936601506000001,-1.7549465219999998,-1446.5940187107772 -2109,2109,L135C,-0.068192055,-0.049227127,-0.023001083999999998,-0.245550479,-1.94117432,0.100961328,-0.075620361,-0.060763749000000006,0.035757594,-0.070038136,-0.028416117999999997,-0.03842676,-0.0075754080000000005,-0.079049642,-0.412051316,-1.742133104,-2.140215535,0.972925785,1.323018354,-10.31277899,-10.60326263,-11.30852621,-9.685007828,-9.835293816,-10.13180445,-8.313445902,-6.262391854,-1448.7081165402196 -2110,2110,L135E,0.007769139,0.029143981,0.009569026999999999,-0.17222915100000002,-1.681275963,0.015336599,0.001090997,0.014447281000000001,-0.091666698,0.030596815,0.027691146,0.036932626,-0.017794573,0.059269577999999996,-0.403727879,-1.696077904,-1.666474021,0.49601981700000003,1.304143634,-9.48113891,-7.940165825,-11.96383719,-7.78771685,-9.823459297000001,-9.890515387999999,-6.647918695,-4.268362122,-1444.1996533158235 -2111,2111,L135D,-0.060098902,-0.8729846440000001,-1.800587346,-2.288358611,-2.91674579,0.004086522,-0.074740738,-0.045457066,0.002506684,-0.820424178,-0.9255451090000001,-1.6953224480000002,-1.9058522430000002,-2.166151115,-2.4105661069999997,-2.732851302,-3.1006402769999997,3.013880227,1.092637207,-13.705596100000001,-12.7784179,-16.37372536,-12.18777766,-14.11613171,-13.07192788,-9.984269775,-9.572265932,-1437.8149015090894 -2112,2112,L135G,0.013196296000000001,0.01755985,-0.8237607140000001,-1.738984132,-2.374463158,0.06270600900000001,0.039844467,-0.013451876000000001,-0.031677281,-0.020063442,0.055183142000000004,-0.617837862,-1.0296835659999999,-1.503191226,-1.974777038,-2.61982839,-2.129097925,2.0856737659999998,1.0868447909999999,-11.02349439,-10.895482800000002,-13.19403145,-8.855890938,-11.35084586,-10.82122091,-7.226935132,-4.897045662,-1446.157910815673 -2113,2113,L135F,-0.014543203000000001,0.011614278,0.012121934,-0.008153599000000001,-1.195243408,0.037900525,0.011665463999999999,-0.04075187,0.068940289,-0.032231694,0.055460249,-0.014307465,0.038551333,0.026693945,-0.043001142,-1.417740095,-0.97274672,0.675350322,1.3239672009999999,-4.925340907,-4.813751976,-4.920964729,-5.7272669910000005,-4.676099884,-4.488620956,-4.947799439,-3.626605222,-1449.6061565228738 -2114,2114,L135I,0.082884663,0.01490221,0.041074387999999996,0.024461122999999998,0.015083205,-0.031827975,0.11898029199999999,0.04678903400000001,0.034212518,-0.029245282,0.059049702,-0.00661439,0.088763165,-0.00057061,0.049492855,-0.04751424,0.077680649,1.493007229,2.630361326,-4.182949367,-5.975792732,-4.25051638,-3.047071709,-4.657408043,-2.98395797,-4.356210632,-0.9945509140000001,-1457.7784164743498 -2115,2115,L135H,-0.053313506,-0.024937072999999997,-0.012673908999999999,-1.172863508,-1.802150135,0.037858204,-0.042277499999999996,-0.064349511,-0.026613831,-0.039582591,-0.010291554,-0.010762826999999999,-0.014584991,-0.9943386540000001,-1.3513883619999998,-2.0590940019999997,-1.545206267,2.188042586,1.507923098,-10.24109932,-9.810795784,-11.23078505,-9.030299918999999,-8.921526611,-12.21208923,-7.03763026,-5.148851805,-1442.6727755507454 -2116,2116,L135K,-0.012480836,0.003177875,-0.030873737999999998,-0.42797057899999996,-1.541480467,0.052686377,0.028258301,-0.053219973,-0.017927976,-0.009625544,0.015981293,-0.007172176,-0.054575299,-0.126402661,-0.7295384970000001,-1.6230536709999999,-1.459907262,1.074426554,1.3447120769999998,-7.985608768,-9.036825653,-10.20333436,-5.804211922,-7.568170265,-7.31550164,-5.156806906,-2.566029227,-1449.455332352547 -2117,2117,L135M,-0.032458600000000004,-0.025005153,0.032575086,-0.006326065,-0.163311658,0.020427028,-0.030792832000000003,-0.034124367,0.004974043,0.024990601,-0.07500090599999999,0.064383968,0.0007662039999999999,0.011470156,-0.024122285,-0.160308867,-0.166314449,1.41972547,2.254221664,-5.157165701,-5.349719574,-6.529141815,-4.862355331,-5.655430312999999,-3.3891814730000003,-5.437422234,-1.3981329040000001,-1454.201768515166 -2118,2118,L135N,0.006785134,-0.009171788,0.001135201,-1.473667881,-2.400954055,0.043084177,0.020420873,-0.006850605,-0.00965376,-0.028013031,0.009669455,0.011812268999999999,-0.009541866999999999,-1.303158894,-1.6441768680000002,-2.3817424419999997,-2.420165667,0.55444544,0.709231611,-11.25833726,-11.30514161,-12.13519597,-10.36597773,-11.39248516,-11.09288583,-8.109246784,-6.111214092999999,-1437.7586986124516 -2119,2119,L135Q,-0.001100287,0.036382714,0.034291793,0.025451976,-1.193573049,0.04227883599999999,0.033919461,-0.036120035,0.048353815,0.040733639,0.032031789,0.054439743,0.014143842,0.055366995,-0.004463044,-1.15516019,-1.231985908,0.688308438,1.340989175,-8.331376596,-5.718701987999999,-11.8915761,-6.718123756000001,-7.140618233,-10.1878629,-6.146894545,-3.4665153810000002,-1450.5451332228258 -2120,2120,L135P,-0.019019823,-1.496527164,-2.0523706230000003,-2.363919347,-2.8530553519999997,0.025867572000000002,-0.009614815,-0.02842483,-0.048074806,-1.466004289,-1.5270500390000001,-1.9643718019999998,-2.140369443,-2.29438497,-2.433453723,-2.594817267,-3.1112934360000004,0.009614745,-0.9341182259999999,-12.67727379,-12.57299569,-14.63686118,-11.46850156,-12.5871069,-12.12090364,-9.984269775,-9.572265932,-1453.5622024820186 -2121,2121,L135S,-0.003435025,-0.0012869469999999999,0.020849316,-0.901277792,-1.8798725930000002,0.016619586000000002,0.041274773,-0.048144822000000004,-0.047999663,-0.015466681000000001,0.012892787,-0.002499217,0.044197849000000004,-0.677903818,-1.124651765,-2.089702045,-1.67004314,1.8485131590000001,1.391908521,-8.43832287,-9.450732719,-9.785154381,-7.220001167,-8.067446167,-7.668279915,-6.166430375,-4.659426326,-1440.7736518215388 -2122,2122,L135R,-0.030322266,-0.019481681,0.007083736,-1.212068172,-1.8918507180000002,0.044034616,-0.026117932000000003,-0.034526599,-0.057566589,-0.010008396999999999,-0.028954964,0.006254381999999999,0.007913089,-0.841499551,-1.582636792,-2.133021546,-1.650679889,1.848576741,1.352505485,-9.231775661,-7.6033299329999995,-10.93156673,-7.558507744,-8.277736572,-11.78773733,-5.935458678,-3.570514906,-1437.2766658728942 -2123,2123,L135T,-0.061223034,-0.009615766999999999,-0.015524672,0.002768015,-1.77295641,0.025871492000000003,-0.071176323,-0.051269745,0.032833041,-0.007684469,-0.011547065,0.011375178,-0.04242452099999999,0.003879482,0.0016565470000000002,-1.482085631,-2.063827189,0.64119709,1.3186931709999998,-8.406645378,-9.007511322000001,-9.84318692,-6.777353172000001,-8.376973969,-8.028201507999999,-6.563926052,-3.884525252,-1447.479771230137 -2124,2124,L135W,-0.023233632,-0.01870029,-0.7126437809999999,-1.724436773,-2.6627183309999998,0.026094698,0.0043791279999999995,-0.050846392000000004,-0.028569748,-0.038741488,0.001340909,-0.44776979200000006,-0.97751777,-1.64030605,-1.808567496,-2.632974969,-2.6924616919999997,1.716388821,0.862657053,-9.355307057000001,-9.383733772000001,-9.918236801,-9.177507729,-7.676531036,-10.62052595,-7.063058527999999,-2.745522269,-1450.052359701367 -2125,2125,L135V,0.035417055,-0.005919798,0.033200827999999995,0.031691952999999995,-0.036550333,0.0038500979999999997,0.024684172,0.046149937,-0.015398708999999998,-0.014764977,0.0029253820000000002,0.024532592000000002,0.041869063,-0.0033825009999999996,0.066766407,-0.047415845,-0.02568482,1.415812981,2.6020213130000003,-4.624903035,-5.070366783,-5.662694664,-3.246710335,-5.019648628000001,-4.125094765,-3.904763051,-1.3900099719999999,-1454.209510116838 -2126,2126,L135Y,0.012562361999999999,-0.000852569,0.003671587,-1.28702811,-2.43111952,0.050933294000000004,0.041564558,-0.016439834,-0.008733995,-0.070080839,0.068375701,-0.020146228999999998,0.027489403,-1.308678598,-1.2653776209999998,-3.031725985,-1.830513055,0.801065692,0.7287268490000001,-7.7630292270000005,-8.572352875,-7.999037819,-7.599189705,-6.751853972999999,-7.892711761,-5.809777577,-4.034836862,-1442.2354476344772 -2127,2127,L136A,-0.047977402,0.00928127,-0.017677571,-0.12551959099999999,-1.717249236,0.012444281000000001,-0.040676587,-0.055278216,0.044319726,0.0033588209999999997,0.015203719,-0.001931135,-0.033424006,0.012688931,-0.263728112,-1.946422787,-1.488075684,0.680394701,1.298568349,-7.1318434879999995,-5.85375518,-7.1536006620000006,-6.327904861,-7.820993301000001,-8.502963432,-5.382692475,-4.1737922,-1454.497260008473 -2128,2128,L136C,-0.11305580800000001,-0.03131713,-0.099447597,-1.307198378,-2.7536823939999997,0.011941016,-0.129508249,-0.096603366,-0.001686899,0.036046841,-0.09868110000000001,-0.012428628,-0.18646656600000003,-1.150514658,-1.463882097,-2.2132697709999998,-3.2940950160000004,0.833857317,0.7549000570000001,-8.707652716,-8.367589942999999,-8.680756942999999,-8.572706841,-9.934712555,-7.982497298999999,-7.05935192,-4.103830045,-1461.1960266754031 -2129,2129,L136E,-0.035618852,-0.789348506,-2.084277019,-2.396207913,-3.025057795,-0.025552081,-0.011584163,-0.05965354,0.045593757,-0.33739655700000004,-1.241300455,-1.648276351,-2.520277686,-2.713322505,-2.0790933209999998,-2.787073003,-3.263042586,1.3275182559999998,0.069593618,-12.03008268,-10.76053468,-12.20629511,-11.63861162,-13.28215435,-12.26281763,-9.762993266,-10.45371609,-1456.8675151076168 -2130,2130,L136D,-0.072914699,-1.455973755,-2.338652659,-2.7130529219999997,-2.768838785,0.074176139,-0.040743257000000005,-0.105086141,0.065907432,-1.5011133140000001,-1.410834195,-2.061280106,-2.616025212,-2.28122822,-3.144877624,-2.6560087130000003,-2.8816688569999998,-0.271717848,-0.947047291,-12.85720479,-12.21537987,-13.03692766,-12.255578,-14.09393658,-12.68420184,-9.762993266,-10.45371609,-1458.1646593953483 -2131,2131,L136G,-0.061058491,-0.022520349,-1.157233897,-2.076595831,-3.003875111,0.021011738,-0.04671705599999999,-0.07539992599999999,0.036435712,-0.004109567,-0.04093113,-1.092033257,-1.222434536,-1.804522985,-2.348668677,-2.621260316,-3.3864899060000004,2.459935651,1.127724855,-11.680655499999999,-11.111664999999999,-11.45060035,-11.25702106,-12.47563342,-12.10835767,-9.043111977999999,-7.87811875,-1459.0918003818952 -2132,2132,L136F,-0.057483584000000004,-0.7031582040000001,-1.7242718369999999,-2.681837811,-2.825669304,0.019302395,-0.07564674,-0.039320428,0.099180835,-0.480647593,-0.925668814,-1.5952327419999999,-1.8533109319999999,-2.555543546,-2.808132076,-2.3282640480000003,-3.3230745589999997,1.6446582630000002,0.169514665,-9.440853313,-9.174938179,-8.878201736,-9.448491074,-10.09091125,-9.611724319,-7.488051102000001,-5.502519691,-1450.9866059147753 -2133,2133,L136I,0.03500675,0.014234416000000001,-0.010748454,0.045077480999999996,-0.17496484899999998,-0.031483614,0.039529694,0.030483805,0.055072857,0.039567842,-0.01109901,-0.011062556000000001,-0.010434352,0.025922618999999997,0.064232342,-0.156499002,-0.193430695,1.220572632,2.066951262,-3.114348335,-2.10352832,-3.616627937,-3.2215591960000003,-3.8873522030000003,-2.742674019,-3.720659491,-1.92446127,-1460.282842460554 -2134,2134,L136H,-0.133611849,-0.961515654,-2.187029892,-2.50685792,-2.539765038,0.055439369,-0.123544906,-0.143678791,0.066465026,-0.67081086,-1.252220447,-1.991030681,-2.383029102,-2.454016844,-2.559698995,-3.129827333,-1.949702742,1.490618306,-0.11357019800000001,-12.88937807,-11.65083229,-12.62560618,-13.14513167,-13.73309621,-13.29222398,-9.762993266,-10.45371609,-1456.6396972518414 -2135,2135,L136K,0.032910394,-1.73043469,-2.014473315,-2.476919208,-2.532705071,0.047366728,0.10006138199999999,-0.034240594,0.093428506,-1.6991243930000002,-1.7617449859999998,-2.192344395,-1.836602235,-2.111262514,-2.8425759010000005,-2.185013011,-2.88039713,-0.697728144,-1.062722563,-12.07154769,-11.28681774,-12.5124899,-11.78379061,-12.48402549,-12.290614699999999,-9.762993266,-10.45371609,-1458.3678590396885 -2136,2136,L136M,-0.029343821000000003,-0.009509011,-0.024946338999999998,-0.002533488,-1.15861749,0.035162413999999996,-0.041315545,-0.017372096,0.01236855,0.002067072,-0.021085093,-0.02502706,-0.024865618,0.009943671,-0.015010646,-0.686702458,-1.630532521,0.9190990640000001,1.4519582080000002,-3.941644365,-3.630144768,-3.65348008,-4.716066772,-3.926100258,-3.782429947,-5.103221506000001,-2.8213464339999996,-1456.0910284095444 -2137,2137,L136N,-0.001632136,-0.484794756,-1.588947401,-2.777542129,-3.07188862,0.025381346000000003,0.042447398,-0.045711669,0.015388638999999999,-0.30439926300000003,-0.6651902479999999,-1.503348853,-1.6745459480000002,-2.1755946390000003,-3.3794896189999997,-2.726466391,-3.417310848,1.457219834,0.158399669,-10.95537372,-10.46876717,-11.01204106,-10.99690937,-12.07986827,-10.21928275,-7.9652306710000005,-5.198272622,-1457.2838717401028 -2138,2138,L136Q,-0.12448723,-0.552065837,-1.688036626,-2.562436889,-2.618222752,0.003310123,-0.046745075999999997,-0.202229383,0.140762384,-0.13627484,-0.9678568329999999,-1.464127449,-1.911945802,-2.286135555,-2.838738222,-2.359886052,-2.8765594510000003,0.935169327,0.06672568400000001,-10.16148378,-8.930022079,-10.65096381,-10.10465358,-9.999408379,-11.12237106,-7.938757164,-7.029747338,-1458.377812239807 -2139,2139,L136P,-0.061274714,-1.51525225,-2.131193669,-2.384797528,-3.068219645,0.023570315,-0.044339724000000004,-0.078209704,0.0055320280000000005,-1.462865425,-1.567639075,-2.033251382,-2.229135956,-2.077108237,-2.692486819,-3.0081912319999997,-3.128248057,3.250659202,0.881743811,-12.02477847,-11.32305422,-11.98575116,-11.44825673,-13.25956449,-12.10726572,-9.74733258,-10.38510711,-1458.2889320133254 -2140,2140,L136S,-0.032698547,-0.0149125,-1.081950833,-1.981957552,-2.769350458,0.042260005,0.008831511,-0.074228604,0.083328179,-0.0063195809999999995,-0.023505419,-0.983593851,-1.180307814,-1.83343105,-2.130484053,-2.7396904610000004,-2.799010455,2.359781327,1.071347823,-9.628428735,-8.825515755,-9.487181686,-9.525306801000001,-10.63305678,-9.671082657000001,-7.669048796,-5.858593899,-1453.7080511976965 -2141,2141,L136R,-0.088540725,-1.489062885,-2.334851848,-2.288505153,-3.417355034,0.018298926,-0.064954425,-0.112127024,-0.034450625,-1.548717559,-1.429408211,-2.079726122,-2.589977573,-1.89390889,-2.683101415,-2.937696165,-3.897013903,-0.19964626100000002,-0.997231489,-12.03356076,-11.51466544,-11.85562979,-11.75152725,-12.5081244,-12.5378569,-9.762993266,-10.45371609,-1456.9990596107673 -2142,2142,L136T,-0.044930806,-0.018432716000000002,-0.034729245,-1.5119941069999998,-2.49032899,0.041582012,-0.028604808,-0.061256804000000005,0.042104697999999996,-0.000748092,-0.03611734,-0.030387585,-0.039070905,-1.268203419,-1.755784795,-2.228010564,-2.7526474160000003,0.8598033690000001,0.736126811,-8.839815788,-8.246984177,-9.612352806,-8.502282845,-8.686276031,-9.151183083,-6.572016099,-5.751164535,-1455.3018987905234 -2143,2143,L136W,-0.09308815,-1.7527600559999998,-2.3483155890000003,-2.847654588,-2.7925160769999997,0.015483998999999998,-0.0678006,-0.118375699,-0.031369569,-1.709389256,-1.796130856,-2.237371365,-2.459259812,-2.105136961,-3.590172215,-2.434159964,-3.1508721889999998,-0.48230219799999996,-1.09202305,-11.63108162,-10.90380845,-11.068470199999998,-11.32970312,-12.80800862,-12.04541773,-9.017207663999999,-7.87811875,-1452.0013870270923 -2144,2144,L136V,-0.035246587999999995,-0.009182113,-0.040336823,0.0027438429999999997,-0.906487138,0.040550342999999996,-0.035048036,-0.03544514,0.057409725999999994,0.011960223,-0.030324447999999997,-0.0010865480000000001,-0.079587097,0.03987811,-0.034390423999999996,-0.7252374979999999,-1.087736777,0.457052479,1.3538469290000001,-3.59190085,-2.259235275,-3.610065979,-3.217830475,-4.880787399,-3.9915851210000004,-3.398659315,-2.0624674919999997,-1460.0953653543256 -2145,2145,L136Y,-0.030087677,-1.7519262580000001,-2.36257114,-2.776562026,-3.181832892,0.0258452,0.036554632999999996,-0.09672998599999999,0.009255314,-1.871550698,-1.6323018169999999,-2.665800696,-2.0593415840000002,-2.186778806,-3.3663452460000003,-2.9594993080000003,-3.404166475,-0.455607935,-1.093465696,-12.52745262,-11.67977261,-12.29079562,-12.65009378,-13.26518274,-12.75141833,-8.875480134,-7.87811875,-1452.0601416840218 -2146,2146,L137A,-0.059570186,-0.017688806,-0.029302322999999998,-0.017461453000000002,-1.775437387,0.043049642,-0.047382848,-0.071757523,0.330993219,0.000985053,-0.036362665,-0.020735485,-0.03786916,0.021220889,-0.056143795,-1.608129146,-1.9427456269999999,1.061440403,1.3460313019999999,-8.162671628,-8.174486465,-8.809668816,-7.404939079,-7.465432045,-8.958831734,-5.9828056929999995,-3.7942326669999997,-1458.7707694126293 -2147,2147,L137C,-0.048967339000000006,-0.037603284,-0.047532978,-0.170590627,-1.808855586,0.081004982,0.008398913000000001,-0.10633359,0.23408320600000002,0.012358085,-0.08756465199999999,-0.037969254,-0.057096702,-0.046426989,-0.294754265,-2.088854525,-1.528856646,0.60703955,1.287184767,-10.97683732,-11.31605009,-10.47656591,-12.42564502,-9.920069519,-10.74585605,-8.342710653,-5.813794026,-1460.7221798077226 -2148,2148,L137E,-0.058991602000000004,0.025528936000000002,-0.019226826000000002,-1.0239925859999999,-2.8850004460000003,0.05734637099999999,-0.032574723,-0.08540848,-0.021189298999999998,0.052137575,-0.001079703,0.005559413000000001,-0.044013064000000005,-0.513327443,-1.5346577280000002,-2.733067882,-3.03693301,1.089601281,0.981572305,-11.47701017,-11.59474796,-11.46526794,-11.93960304,-10.71418007,-11.67125184,-7.853488484,-5.553313135,-1470.9878625674173 -2149,2149,L137D,-0.008079952,-0.34447346799999995,-1.507554579,-2.07133342,-3.145786752,0.065983242,0.011982738,-0.028142641,0.507084478,-0.094638326,-0.59430861,-1.45213329,-1.5629758669999998,-1.9204101519999999,-2.2222566880000003,-2.917759313,-3.37381419,2.5822294180000003,1.078781934,-13.71807731,-13.60663083,-14.00673497,-14.11059231,-12.67638992,-14.19003853,-10.171095,-9.715937357,-1473.5766268186271 -2150,2150,L137G,-0.037342002,-0.004236591,-0.046279539,-1.0880812229999999,-2.270538407,0.057072169000000006,-0.021038887000000003,-0.053645116,0.054322569,-0.011380731000000002,0.002907549,-0.060599125,-0.031959952,-0.674595548,-1.5015668969999998,-2.195657834,-2.34541898,1.7215269919999998,1.329705029,-11.83380367,-12.44707608,-11.49548137,-11.30909789,-11.16332382,-12.75403921,-7.708159515,-4.862640782,-1470.5705878790468 -2151,2151,L137F,0.018682968,0.010123453000000001,0.036700991,0.020510729,-0.950327725,0.129616703,0.05532672,-0.017960784,0.029963222999999997,-0.026176527,0.046423433,0.015138875,0.058263107,0.045627562999999996,-0.004606105,-0.761463254,-1.139192195,0.582916593,1.366205451,-6.908805071000001,-7.754445572000001,-5.817833855,-8.553684752999999,-6.113210518,-6.304850655,-4.240069419,-1.4197225169999999,-1457.6824853625149 -2152,2152,L137I,0.005518566999999999,-0.049275277,-0.003329892,0.045246330999999994,-0.155949816,0.017372823,0.034788184,-0.02375105,0.17609125899999997,-0.028526187,-0.070024367,0.022054515,-0.028714298,0.032424087000000004,0.058068575,-0.123266251,-0.18863338,1.196778844,2.1816340380000003,-4.889278818999999,-4.7071694410000005,-4.784677605,-3.5409266660000003,-5.208375877,-6.205244507000001,-4.167821289,-0.501860826,-1460.7225129338913 -2153,2153,L137H,-0.025899914,-0.034918216,-0.06977432900000001,-1.561841382,-2.716401962,0.066766967,-0.010502491999999999,-0.041297336000000004,0.37841786899999996,-0.039828896,-0.030007536,-0.10014329300000001,-0.039405365,-1.3500773330000002,-1.77360543,-2.7184943560000003,-2.714309567,0.918048883,0.7398249290000001,-11.82039254,-11.00237223,-11.63715829,-13.79455672,-9.94888459,-12.71899088,-7.301555472,-5.489362878,-1471.35062650498 -2154,2154,L137K,-0.029615044,-0.09416432599999999,-1.819391843,-2.481318007,-3.0060790230000003,0.108637071,0.010184707,-0.069414795,-0.06694679,-0.17246611,-0.015862542,-1.600385019,-2.038398666,-1.88361578,-3.0790202339999997,-2.8229729939999997,-3.1891850510000004,2.769547998,1.13690377,-13.41062022,-13.40594216,-13.76779122,-13.82232706,-11.85139246,-14.20564821,-8.939746547,-6.714215116,-1470.8541278932244 -2155,2155,L137M,-0.00460215,-0.01866199,-0.08038719799999999,-0.025088762,-0.14725794,0.058706720999999996,0.011762048,-0.020966347,0.21901946,0.012652848000000001,-0.049976828,-0.117599698,-0.043174697000000005,-0.035911119,-0.014266404,-0.121061781,-0.17345409899999997,1.654077292,2.5155582969999997,-4.847081284,-5.139874443,-4.474568428,-4.352966621,-4.964768867,-5.303228058,-4.979974167,-2.0903621880000003,-1454.6893789302558 -2156,2156,L137N,-0.034257837,0.015508491000000001,0.008805354,-0.97297948,-2.765156307,0.055053434000000005,-0.0062823290000000006,-0.062233345,0.029963222999999997,0.067016575,-0.035999592999999996,0.020146615,-0.002535908,-0.512136259,-1.4338227,-2.051826645,-3.478485969,1.715318251,1.373429946,-13.321713800000001,-13.66070147,-12.71609892,-14.67506841,-12.11220952,-13.44449068,-10.171095,-9.715937357,-1470.9154317807406 -2157,2157,L137Q,-0.040344377,0.00040302199999999995,-0.07072099400000001,-0.505934979,-2.0692031969999998,0.054967972999999996,-0.037559413,-0.04312934,0.081115746,-0.015649736,0.016455779,-0.097816642,-0.043625345,-0.157886805,-0.8539831520000001,-1.76315697,-2.375249424,1.198357464,1.3468867709999999,-11.12768213,-11.81137198,-11.33487238,-11.62717197,-8.484181305,-12.380813,-7.501002281,-2.888098375,-1467.8192336056381 -2158,2158,L137P,-0.018884048,-1.468272325,-2.020665783,-2.22412534,-2.743316825,0.066169539,-0.013662921000000001,-0.024105174,0.27741039100000003,-1.496621212,-1.4399234369999998,-1.8986904480000002,-2.1426411169999997,-2.061781355,-2.386469324,-2.572463944,-2.914169706,-0.408588164,-0.899299996,-13.17848505,-13.54812634,-12.93964551,-13.71106385,-12.345912599999998,-13.34767696,-10.171095,-9.715937357,-1469.8936139871366 -2159,2159,L137S,-0.053561657,0.003637545,-0.019523197,0.001497737,-1.799622821,0.08319233,-0.026517658,-0.080605655,0.09123288,0.028099724,-0.020824635,0.016222999,-0.055269393,0.060843612000000005,-0.05784813900000001,-1.582282489,-2.0169631519999998,0.44026499700000005,1.30604665,-9.802663397,-10.29355078,-9.505205582,-10.50366345,-9.044688286,-9.666208885,-7.0576053860000005,-4.443296035,-1463.8128395490348 -2160,2160,L137R,-0.057799387,-0.822449487,-1.92787599,-2.474269126,-2.957709252,0.067388749,-0.035646852,-0.07995192200000001,0.302964495,-0.63032153,-1.0145774440000002,-1.936251189,-1.919500791,-2.282063934,-2.666474317,-2.69508187,-3.2203366339999997,0.164576139,-0.5428212370000001,-12.36927197,-12.13331377,-12.2946601,-13.15176981,-10.78019717,-13.48641898,-7.99496215,-4.655326925,-1469.8590492978692 -2161,2161,L137T,-0.012596648,-0.031520482999999995,-0.01765207,-0.003388147,-1.083467725,0.038812558,-0.023216565,-0.0019767310000000002,0.37580556299999995,-0.039194553,-0.023846412,-0.028570123,-0.006734016999999999,-0.004822058,-0.0019542360000000003,-0.8461328579999999,-1.320802592,0.48939432200000005,1.345857211,-7.688504807,-8.000066413999999,-9.032793381,-7.214277602999999,-6.977488815,-7.21789782,-5.724993662999999,-3.661306259,-1456.3777855355293 -2162,2162,L137W,-0.07665665299999999,-0.028338846,-0.017399263999999998,-1.4875077019999998,-2.888567291,0.042404742,-0.057745791,-0.095567514,0.19836765399999998,0.025985205,-0.082662897,0.013834523,-0.048633051,-1.095151733,-1.8798636709999998,-2.464886798,-3.312247783,0.645899981,0.732335813,-11.05812986,-10.85102834,-9.857675934,-12.8840747,-9.449468887,-12.24840146,-7.254605268,-4.505841748,-1463.9247860517353 -2163,2163,L137V,0.0014342489999999999,0.017019573,0.012496782,0.0011468510000000002,-0.698817295,0.023071781,-0.004336339,0.007204836,-0.053011012,0.030554849,0.003484297,-0.002203665,0.027197229,0.010547091000000001,-0.00825339,-0.546822623,-0.8508119670000001,0.676998478,1.417117489,-5.499788724,-6.183608322,-6.523427696000001,-4.395052444,-4.022797218,-6.374057937999999,-5.422165484,-2.414711155,-1449.959858898539 -2164,2164,L137Y,-0.038573701,0.007598906,-0.062500844,-0.019695795,-0.46206087,0.19294429800000001,-0.030018146000000002,-0.047129255999999994,0.029963222999999997,0.026225927000000003,-0.011028116000000001,-0.037343034,-0.087658654,-0.021549782000000003,-0.017841807,-0.349892162,-0.574229577,1.306619061,1.8908595780000002,-10.98657814,-11.53160198,-10.32337232,-12.60866045,-9.083337936,-11.38591801,-7.0166262,-4.612125506,-1462.4758650101721 -2165,2165,T138A,0.047300826,0.033895921,0.03309556,0.037385547000000005,0.009399046,-0.033673406,0.023038812000000002,0.07156284,-0.018499736,-0.007626371,0.075418212,0.025814936,0.040376184,0.021642391,0.053128703,-0.0072014290000000005,0.025999521,1.1984599329999999,2.588343014,-0.619875897,-0.7021566309999999,-0.204951721,-0.380359764,-0.907214874,-0.904696495,-2.748109517,1.476183038,-1462.0549609879963 -2166,2166,T138C,0.031323059,0.031112032,0.07031865400000001,0.09050691,-0.34071976,0.041745902,0.048508617999999996,0.0141375,-0.022660938,0.03477586,0.027448204,0.016868872,0.123768435,0.091473198,0.089540621,-0.13738056099999998,-0.5440589579999999,1.16738291,2.1103258559999998,-5.701370988,-4.881204811,-6.029146202000001,-5.853961655,-5.848124725,-5.894417549,-7.082669196,-3.73963013,-1454.2978802095167 -2167,2167,T138E,0.043012374000000006,0.029564128,0.061262831,0.06456846299999999,0.009167938,0.04549634599999999,0.020852711,0.065172037,-0.021144134,-0.061684693,0.120812949,0.07540983700000001,0.047115824,0.092176001,0.036960925,0.017746939,0.000588937,1.252694668,2.763475511,-0.11589046300000001,-0.711804497,-0.214925835,0.509771454,0.285982018,-0.448475456,-1.8714484059999998,1.7933604369999998,-1457.3278909884393 -2168,2168,T138D,0.04518757599999999,0.0103214,0.04738805,0.032292424,-0.03346632,-0.01512057,0.035489412000000005,0.054885739,-0.023030752,-0.036762645,0.057405445,0.024052762000000002,0.070723337,-0.000714056,0.06529890299999999,0.032118804,-0.099051444,1.195477376,2.8057874419999997,-1.251198177,-0.9184489290000001,-1.446336235,-1.24758419,-0.73636747,-1.907254059,-3.011889671,2.283162135,-1455.980497510638 -2169,2169,T138G,0.012043052,0.016113486,0.022302798,0.044071208,-0.000496644,-0.029698976000000002,-0.017221534,0.041307637,-0.019880025,-0.005029777,0.037256748,0.037313069,0.007292526,0.053595372,0.034547043,-0.019656159,0.018662872,1.6804900280000001,3.618873133,-3.0200615460000004,-1.6325158919999998,-3.15940416,-3.494865265,-2.426443985,-4.38707843,-3.9332418789999997,0.493101668,-1459.9116509263404 -2170,2170,T138F,-0.10933271800000001,-0.10107327699999999,-0.030072788,-0.032378236,-0.20625038,0.004086483,-0.131105323,-0.087560112,0.00703297,-0.013094493,-0.18905206100000002,0.04975692,-0.109902496,0.018471374,-0.083227845,-0.092780228,-0.31972053100000003,1.280358879,2.291602782,-5.8896743670000005,-5.996547592000001,-6.5560890579999995,-6.237256682999999,-4.569076958,-6.089401542999999,-6.919952167000001,-3.801646251,-1451.571003517136 -2171,2171,T138I,0.088651516,0.09099836800000001,0.100352447,0.10238914199999999,-0.022101147999999998,0.023902534,0.07989803200000001,0.097404999,-0.016398604,0.059483755,0.12251298099999999,0.11257063099999999,0.088134263,0.051854234000000006,0.152924049,-0.029806966,-0.014395328999999998,1.182217169,2.487005351,-6.503337865,-6.738075821,-6.88703685,-7.085261696,-5.580189926,-6.2261250310000005,-7.578886262999999,-4.6686912419999995,-1456.227820461616 -2172,2172,T138H,-0.0028232829999999998,-0.032448141,0.066558357,0.035001093,-0.048618792,0.026129749,-0.031164378,0.025517812,0.003584874,0.046157808,-0.11105409,0.086593031,0.046523682999999996,0.074526768,-0.004524582,0.052710358,-0.149947942,1.0295571959999998,2.74375402,-3.2588947139999997,-2.937899055,-4.229243988,-2.903146004,-1.861804543,-4.362379982,-3.662103498,-0.181824249,-1454.6691086031497 -2173,2173,T138K,0.18876250100000003,0.127911637,0.17258073699999998,0.140823749,0.081894723,-0.163015759,0.171044082,0.20648091899999998,0.069320617,0.136096794,0.11972648,0.109039762,0.23612171199999998,0.135647568,0.145999929,0.140520255,0.023269191,1.012074933,2.9732117689999997,-0.74079278,-0.754550018,-1.32689975,-0.413400566,-0.12274730699999999,-1.0863662570000001,-2.18914918,1.5212771019999998,-1462.737457078416 -2174,2174,T138M,0.063857459,0.027988403999999998,0.110062385,0.09515017199999999,0.003602955,-0.000510161,0.085296355,0.042418563,0.060945994,0.059049678,-0.00307287,0.130048142,0.090076628,0.108417915,0.081882429,0.047911475,-0.040705566,1.054790213,2.757281957,-6.478669883999999,-6.622152229,-6.7187331089999995,-6.883342415,-5.842077712999999,-6.3270439529999996,-7.486823557999999,-4.785134558,-1454.5866059651598 -2175,2175,T138L,0.035639024,0.006976589,0.073702054,0.09896232199999999,-0.04413855,0.032603291,-0.019598089,0.090876136,-0.051850585,0.027868592999999997,-0.013915415,0.078398552,0.069005556,0.09178867800000001,0.106135966,0.003774597,-0.09205169699999999,1.1910484890000002,2.822820842,-5.143076768,-5.719406349,-5.926114997999999,-5.7391971360000005,-4.259243896,-4.071421463,-6.157196101,-2.419191085,-1448.5080688782036 -2176,2176,T138N,0.101419925,0.078614015,0.098621125,0.138190956,-0.011422068999999998,-0.046585455,0.041236768,0.161603081,-0.01257805,0.051045362000000004,0.106182667,0.109185035,0.08805721400000001,0.183161729,0.093220182,0.10086023599999999,-0.123704374,1.080463619,2.978678781,-1.25742303,-1.180660187,-1.5125796969999998,-1.140663269,-0.6887606959999999,-1.7644513019999999,-3.869707775,0.460018717,-1461.6874451003969 -2177,2177,T138Q,0.0034842659999999998,-0.039107189,0.0927326,0.10796978800000001,-0.022462671,0.138802931,-0.030004657999999997,0.036973189,-0.050265497,0.005126093,-0.08334047,0.062131821,0.123333379,0.04754547,0.16839410600000002,0.006952867,-0.051878209,1.462503487,2.934736795,-1.465633731,-1.7606166380000001,-1.986450806,-1.290158478,-0.871731934,-1.4192108,-2.569861971,0.317770603,-1455.4449294591323 -2178,2178,T138P,-0.01933727,-0.003135185,0.032505371,0.023976012,-1.637176164,0.093063421,-0.026334899,-0.01233964,-0.05373330000000001,0.0006300219999999999,-0.006900391,0.060587192000000005,0.00442355,0.05522816,-0.007276136999999999,-1.460567173,-1.813785154,0.133562332,1.300167792,-4.711331203,-4.730882118,-4.86491111,-4.168256203,-3.697396065,-6.095210517999999,-4.723126262,-0.49626545899999996,-1458.6937178415246 -2179,2179,T138S,0.028018352000000003,0.026674087000000003,0.056585435,0.037171261000000004,-0.005663247,-0.011422953999999999,-0.004388116,0.06042482,0.0035869409999999997,-0.013252228999999999,0.066600403,0.053957973,0.059212895999999994,0.032250088999999996,0.042092433,-0.017987559,0.006661065999999999,1.285028742,2.621503574,0.11408441,0.445953514,-0.157487549,-0.041675995,-0.258152901,0.581784981,-0.7458139359999999,0.231032293,-1458.7372997049242 -2180,2180,T138R,0.040804709,0.011912368999999999,0.069178457,0.067143603,-0.014866236000000001,-0.045333987,-0.010243179,0.091852596,-0.046667684,0.023845137000000002,-2.0399999999999998e-05,0.066280107,0.072076807,0.08920708699999999,0.045080117999999995,0.018303719,-0.04803619,1.6804900280000001,3.618873133,-2.406187067,-1.454644073,-3.4805017780000003,-3.049792625,-0.69397155,-3.352025307,-3.618059727,2.275344989,-1456.1180917667225 -2181,2181,T138W,0.037425821,0.035226216,0.032468781,0.074664026,-0.048985812999999996,-0.037772997,0.010948853,0.063902788,0.035052982999999996,0.017582098,0.052870334000000005,0.050834868,0.014102693999999999,0.056105197999999995,0.09322285300000001,0.018793376,-0.116765001,1.2346776529999999,2.7720365339999997,-6.049598035,-5.256636841000001,-6.253641373,-6.571203102,-3.9765164719999997,-8.189992386,-6.13662106,-2.0268323169999998,-1446.5560940778814 -2182,2182,T138V,-0.0077818290000000005,0.008948164,0.0025209620000000003,0.014650848999999999,-0.070479439,0.00930826,-0.017767595,0.002203937,0.04425778,-0.014206189,0.032102517000000004,0.015230802,-0.010188878,0.039015203,-0.009713505,-0.053140767,-0.08781811,1.151075495,2.271329932,-4.500710762,-4.95806839,-4.431795967,-5.18366317,-3.369942093,-4.56008419,-5.559889028,-2.198940296,-1459.581986406818 -2183,2183,T138Y,-0.042695915999999993,-0.015842156,0.09089455800000001,0.043143909,-0.063154918,-0.039259692,-0.068316717,-0.017075115,0.01703859,0.019052382,-0.050736694000000006,0.124309034,0.057480080999999995,0.12422468,-0.037936863,-0.001711975,-0.12459786099999999,1.248566977,2.72936441,-5.565269262999999,-5.387578673999999,-6.194828827,-5.440557869,-3.9275740810000004,-6.875806862,-5.826258987999999,-2.98310817,-1453.079892099835 -2184,2184,T139A,-0.068814666,-0.084822052,-0.028455638,-0.061575804000000005,-0.021554077,-0.006237436999999999,-0.046789933,-0.090839399,-0.07722349099999999,0.016809625,-0.18645372899999998,0.046408019,-0.103319294,0.055367005999999996,-0.17851861300000002,-0.001767815,-0.041340338,1.124142478,2.527128261,-1.7044294309999999,-1.263338905,-1.353040962,-2.19481002,-1.7556530380000002,-1.95530423,-3.099639194,0.594066046,-1458.9590649646707 -2185,2185,T139C,-0.038255576,-0.024917526000000002,0.00944258,-0.01251257,-0.169138366,0.10583220800000001,-0.025060911,-0.05145024,-0.012773968,0.046075772,-0.095910824,0.110043747,-0.091158587,0.11570486099999999,-0.14073,-0.090883428,-0.247393303,1.147806515,2.2973316980000003,-8.001510944,-6.596403114,-8.006027832000001,-8.985307495,-8.877137398,-7.5426788789999994,-7.353744607,-3.600680694,-1460.8502475959249 -2186,2186,T139E,0.012108842,-0.013135738999999999,0.049405877,0.015980112,0.053101457000000005,-0.050680974000000004,0.012814103,0.011403581000000001,-0.014195555,0.06727843900000001,-0.093549917,0.078359691,0.020452062,0.07627919,-0.044318965999999994,0.09944827,0.006754643,1.266944575,3.040825888,-5.6800548189999995,-4.043139641000001,-6.1179767,-7.631993713,-6.273864815,-4.333299225,-4.953453838,0.96762564,-1454.0171761002857 -2187,2187,T139D,-0.041222175,-0.054091245,0.024893093999999998,0.027184041000000003,-0.217867719,-0.001273039,0.020034042,-0.102478391,-0.012282685,0.029811927999999998,-0.13799441699999998,0.09040210900000001,-0.040615922,0.128451132,-0.074083051,-0.087673283,-0.348062155,1.402202694,2.575328355,-7.887607301,-5.249495743,-8.858196541,-8.904714287000001,-9.406368323999999,-7.019261612,-6.292161615,-0.971276204,-1443.3655396194663 -2188,2188,T139G,-0.033385256,-0.071951285,-0.027303179,-0.042742404000000005,-0.11763835199999999,-0.023782131,-0.014934061,-0.051836451,-0.031479599,-0.021917256,-0.12198531300000001,-0.006612505,-0.047993852999999996,0.033266076,-0.118750884,-0.077655636,-0.157621067,1.339728546,2.4291681730000003,-4.869552748,-4.109223595,-4.39698864,-5.069132408,-6.063202782,-4.709216316,-5.200381608,-2.146168406,-1459.6789340269752 -2189,2189,T139F,-0.085580215,-0.064471739,-0.016598821,-0.073303858,-1.379021899,0.020416706,-0.07899041400000001,-0.092170016,-0.046436303,-0.041392685,-0.08755079199999999,-0.006269869,-0.026927773,0.013806738999999998,-0.160414455,-1.247995213,-1.510048584,0.671421705,1.333507755,-8.977303757,-8.195932915,-9.480024185,-9.597422218,-9.69720137,-7.915938095,-6.22776193,-1.050381707,-1458.1691570067778 -2190,2190,T139I,-0.101361972,-0.046653365999999995,-0.032759277,-0.079258122,-0.035725821,-0.035481083,-0.096387961,-0.10633598300000001,0.014339796,0.045102092999999996,-0.138408824,-0.0006949110000000001,-0.064823643,0.029548513,-0.18806475600000003,0.00250707,-0.073958711,1.244514001,2.707780622,-7.272871365,-5.4955096889999995,-8.765267921,-7.857451537999999,-7.962367828,-6.28375985,-5.895342155,-0.329813973,-1454.5562838818878 -2191,2191,T139H,-0.11503412,-0.132290938,-0.081671372,-0.106540068,-0.33664360299999996,-0.027777918,-0.112495156,-0.11757308400000001,-0.046861099999999996,-0.08177184700000001,-0.18281002899999999,-0.019938002,-0.143404741,0.009718898,-0.222799033,-0.23493169100000003,-0.438355515,1.8090060730000002,2.424468709,-4.770661147,-4.918910202,-4.298344734,-5.359063507,-5.878014618,-3.3989726719999998,-5.168105079,-0.314568917,-1454.8844058490358 -2192,2192,T139K,0.049809395,-0.07677987900000001,-0.011363966000000001,-0.019848901000000002,-1.1341245709999999,-0.000677767,0.066716829,0.03290196,-0.033428787,-0.033423755,-0.12013600199999999,-0.06875932,0.046031388,0.05150496,-0.091202761,-0.971251605,-1.296997537,0.65130628,1.351647927,-4.853296548,-4.029463821,-3.425359406,-5.9259255070000005,-5.662410675,-5.223323334,-3.491674984,0.253644947,-1452.4103665763978 -2193,2193,T139M,0.0076139169999999996,-0.09064492800000001,-0.012907674,0.028126169,-0.095383625,-0.057320323,-0.015770139,0.030997972000000002,-0.08882917300000001,0.0038188659999999998,-0.185108722,0.027951478999999998,-0.053766826,0.08463101599999999,-0.028378679,-0.028609887,-0.162157363,1.361151851,2.6363844690000002,-7.465278989,-5.680759407,-8.31283355,-9.44532695,-7.044448868,-6.843026169,-5.589018082000001,-0.6724230999999999,-1460.6314041456208 -2194,2194,T139L,-0.066674262,-0.11065359,-0.008909528,-0.058212858,-0.040313798,-0.0018838479999999998,-0.050620774,-0.082727749,-0.02180566,-0.008000286,-0.213306893,0.01991538,-0.037734435,0.065571084,-0.1819968,0.031705481,-0.11233307599999999,1.169188176,2.8064546289999996,-7.335669307000001,-5.4061295320000005,-8.432587692,-8.07676017,-9.124375587000001,-5.638493552999999,-4.093426698,1.766956728,-1460.0234943665564 -2195,2195,T139N,-0.036150597,-0.061296354000000004,0.0044178740000000005,-0.01934973,-0.08169222200000001,-0.077122364,-0.029644077,-0.042657117,-0.049151488,0.00799909,-0.13059179699999998,0.019685427,-0.010849679,0.04908873,-0.087788189,-0.056070283,-0.10731416099999999,1.2133435590000001,2.3989563869999997,-4.289839668,-3.072246208,-4.7381367260000005,-4.78121582,-5.543461174,-3.3141384119999997,-5.260512516,-1.7493460230000002,-1455.299277557293 -2196,2196,T139Q,-0.007160631999999999,-0.092551175,0.027528917000000003,-0.009708671,-0.02812127,-0.020176265,0.030082223999999998,-0.044403488,0.095107619,-0.0026794270000000003,-0.18242292300000001,0.037190215,0.017867618000000002,0.10425724,-0.12367458099999999,0.07076755,-0.127010089,1.210047111,2.96515002,-4.957104672,-4.529134132,-4.366084723999999,-5.959701355,-6.028862792999999,-3.9017403560000004,-4.105781196000001,0.31279392,-1462.2168801531661 -2197,2197,T139P,-0.08103953700000001,-0.050579470999999994,-0.021264476,-1.3472554190000001,-2.120888247,0.048276014000000006,-0.047742680999999995,-0.114336392,-0.022486701,0.008828978000000001,-0.109987919,0.021271925,-0.06380087599999999,-1.045726758,-1.6487840790000001,-2.20208922,-2.039687273,2.083473241,1.4230199019999998,-6.112336207999999,-4.714641647,-6.524118422999999,-7.468125092,-6.6979776,-5.156818275,-6.703137936,-3.511979155,-1454.3051893473603 -2198,2198,T139S,-0.044946522999999995,-0.064014906,0.00019114299999999998,-0.03940912,0.024660069,-0.036218837000000004,-0.036996968,-0.052896077,-0.035628087999999995,0.0018025889999999998,-0.129832401,0.066506864,-0.066124578,0.07627919,-0.15509743,0.062573643,-0.013253506000000002,1.067914636,2.733284345,-0.820967345,-0.372434471,-0.534967979,-1.097303017,-1.240348564,-0.859782692,-2.638117652,0.186264688,-1459.4759841884952 -2199,2199,T139R,-0.052422042,-0.059192942000000005,-0.0016262689999999998,-0.02455481,-0.18923676,0.011926443,-0.035388666,-0.069455418,-0.022998914,0.025477312999999998,-0.143863197,0.046365792,-0.049618329,0.059044661,-0.10815428,-0.097563625,-0.280909894,1.393694966,2.42738618,-3.6195950010000004,-3.290144119,-3.683483253,-4.289686134,-4.36979039,-2.464871109,-4.745185276,1.5298017780000002,-1454.7686871376354 -2200,2200,T139W,-0.162740277,-0.137622911,-0.036385424,-0.11115719999999998,-1.634384635,0.061127460999999994,-0.147503133,-0.17797742,-0.012931833,-0.012435938,-0.262809883,0.020708501,-0.093479349,0.044665536,-0.266979935,-1.5474649390000002,-1.72130433,0.141842937,1.299659318,-9.61720569,-8.320450362999999,-9.399846443,-11.30443879,-10.26024358,-8.801049277999999,-6.739993601,-2.864572243,-1449.4672736097127 -2201,2201,T139V,-0.074843635,-0.10531397099999999,-0.055796759,-0.055646363,-0.055610984,0.052907012999999996,-0.057064889,-0.09262238,-0.005331075,-0.001025076,-0.209602865,0.009613087,-0.121206605,0.064450547,-0.175743273,0.024368041,-0.135590008,1.146717002,2.694846918,-5.692967595,-4.864584244,-6.271646682999999,-5.785844902000001,-6.154010246,-5.3887519,-4.380703887,-0.31034032,-1458.8087850138545 -2202,2202,T139Y,-0.022793172999999996,-0.03330858,-0.008240303000000001,-0.036428688,-1.324513524,0.072833302,0.019599918,-0.065186263,-0.024926193,0.025004712000000002,-0.091621871,-0.008486739,-0.007993867,0.037975825,-0.11083319999999999,-1.193390513,-1.455636535,0.6279090270000001,1.33311386,-7.7514651,-7.402319672000001,-7.39843898,-9.13065213,-7.875870612999999,-6.950044106,-5.708911434,-0.381700702,-1455.6921181306243 -2203,2203,I140A,-0.06267311099999999,0.073692535,0.047544496,0.061307204000000004,-1.498297601,0.09263537300000001,0.0694177,-0.194763921,0.020994227,0.095606069,0.051779001,0.022903217000000003,0.07218577400000001,0.085816815,0.036797592999999996,-1.3731842580000002,-1.623410944,0.225454015,1.305838508,-4.391328032,-3.057601669,-4.291975555,-6.626827598999999,-4.118591888,-3.861643448,-4.459707736,-1.145191496,-1450.6196493874304 -2204,2204,I140C,0.060230927000000004,0.020351479,0.022412615,0.012819656,-1.437943051,0.072517243,0.052623242,0.067838611,0.03339708,0.036575926,0.004127031,-0.001297593,0.046122822,0.041573634,-0.015934323,-1.2849749259999999,-1.5909111759999999,0.673691796,1.331636422,-7.0517802960000004,-5.2951173780000005,-6.284349487,-10.78031923,-6.803809967,-6.09530542,-6.064350748,-3.71908382,-1448.3955117585137 -2205,2205,I140E,0.069990676,0.016015876000000002,-0.024020345,-1.312140447,-2.106084455,-0.001810865,0.079196425,0.060784927,0.063619971,-0.019683944,0.051715695,-0.02543609,-0.022604599,-1.160437143,-1.46384375,-2.098440118,-2.113728792,2.248885612,1.493137515,-9.076833817999999,-6.8742016679999995,-9.031281273,-12.42086936,-8.773223418999999,-8.284593369,-8.094582497000001,-6.534454729,-1450.4514608001336 -2206,2206,I140D,0.03945061,-0.082263398,-1.409062161,-2.2373470109999998,-3.26519342,0.034310776,0.056096632,0.022804587999999997,0.010831252,-0.035594947,-0.12893184800000002,-1.1936309390000002,-1.6244933819999998,-2.151536584,-2.323157437,-2.98039509,-3.54999175,2.162399835,0.7663971559999999,-10.22404447,-7.985114014,-9.895039581,-14.16392251,-9.902371283999999,-9.173774963,-8.834125656,-8.932049556,-1450.476590976119 -2207,2207,I140G,0.018111691,0.007052981999999999,-0.00685681,-1.010761062,-1.734219462,0.06500602400000001,0.065852203,-0.029628822000000003,0.025782821,-0.014947803999999999,0.029053767999999997,-0.054695415,0.040981795,-0.633551552,-1.387970572,-2.024961508,-1.443477415,1.836396175,1.4121174459999999,-7.442145476,-6.192971458,-6.933194893,-10.33661476,-6.522277442999999,-7.2256688229999995,-5.912435102999999,-3.97427313,-1445.0242394460365 -2208,2208,I140F,0.099751373,0.035192389,0.058018158,0.048891695,-0.18441350399999998,-0.043800654,0.112191326,0.08731142,0.029792955,0.03247182,0.037912957000000004,0.067053782,0.048982532999999995,0.046496311,0.051287079000000006,-0.146057545,-0.222769462,1.3556879290000001,2.250613978,-4.551839363,-3.3718334660000004,-3.707402824,-7.374999855,-4.147935242,-4.157025429,-3.925736096,-1.757039035,-1452.4169335258193 -2209,2209,I140H,0.053201451,0.016202885,-0.010349353,-1.352290775,-2.596333523,0.043106427,0.066838884,0.039564018,0.02484058,-0.009077489000000001,0.041483259,-0.02148576,0.0007870539999999999,-0.9720121490000001,-1.7325694,-2.129174735,-3.06349231,2.074338269,1.4305973140000001,-9.007478189,-6.092997498,-8.213595444,-14.82009936,-8.110594025,-7.800104622,-5.785983348999999,-4.604322027,-1450.674293342512 -2210,2210,I140K,-0.019354467,0.009653039,-0.755288815,-1.583831486,-2.431673968,0.014636233,-0.0176,-0.021108934,0.010156657,0.016915291000000002,0.002390787,-0.545351194,-0.965226435,-1.62751646,-1.540146512,-2.678223715,-2.18512422,1.8908223530000001,0.9345785040000001,-9.948549683,-7.993138504,-9.691270615,-13.35750648,-9.368353477000001,-9.33247934,-8.834125656,-8.932049556,-1458.2205854682252 -2211,2211,I140M,0.08725681699999999,-0.008758017,0.008632844,0.007953198,-0.036978727999999995,-0.018402044,0.091133522,0.083380112,0.044295304,0.008393905,-0.025909937999999997,0.0047379679999999995,0.012527719,-0.047732863,0.063639259,-0.076297373,0.002339917,1.340737958,2.341323869,-3.029273608,-2.727958183,-3.076508118,-2.9337780689999997,-2.882379715,-3.525743958,-4.282813613,-2.341671581,-1452.7109960294329 -2212,2212,I140L,0.07648165,0.023758592999999998,0.027289617999999998,0.010490571,0.024254683,-0.013618403999999999,0.06943971,0.08352358900000001,0.052960821,0.007124233000000001,0.040392952,0.000148639,0.054430597000000004,0.007452816,0.013528326,0.031525135,0.01698423,1.165838882,2.697555098,-0.387422964,0.130186623,-0.221735603,-0.325719231,-1.1021122970000001,-0.417734314,-1.992379022,0.698512293,-1461.7466342947446 -2213,2213,I140N,0.060406195,-0.016507451,-0.023164344,-1.042676006,-2.209628613,-0.007546703,0.071725777,0.049086613,-0.06634222299999999,-0.039693207,0.006678306,-0.067175222,0.020846535,-0.4994415,-1.5859105119999999,-1.93236598,-2.486891245,1.667191505,1.389788981,-8.558362178,-6.272047424,-8.384725624,-12.82717556,-8.061089516000001,-7.246772766,-6.775764958,-5.464381679,-1452.52776029706 -2214,2214,I140Q,0.03940386,0.002884432,0.00332688,-0.01836465,-1.4192500559999999,0.047185677,0.020449731000000002,0.058357988,0.052300295999999996,-0.008094344,0.013863208,-0.000470343,0.007124101999999999,0.039076823,-0.075806122,-1.509685594,-1.328814517,0.657442112,1.318723729,-7.314276936000001,-4.372728508,-7.600938065,-11.12410686,-6.80433931,-6.669271935,-5.912103146000001,-4.136170245,-1451.1094932276756 -2215,2215,I140P,0.010490496,-0.5504080029999999,-1.739585811,-2.114375231,-2.74499476,0.052842994000000004,0.019451566,0.001529426,0.044033395,-0.306655117,-0.794160888,-1.967889199,-1.5112824230000002,-2.11961487,-2.109135591,-2.726624627,-2.763364892,1.062682211,-0.08540157599999999,-9.772675694,-8.273721886,-9.620288147,-12.69573434,-9.520983795,-8.752650307,-8.620421317,-8.089070996,-1463.4044742891565 -2216,2216,I140S,0.014603686000000001,-0.0049878679999999995,-0.022106543,-0.107281797,-1.5636817159999998,0.049911566,0.022490512999999997,0.006716859,-0.013803886000000001,-0.020107364,0.010131628,-0.054945637,0.010732552,-0.027291702999999997,-0.18727189100000002,-1.709754833,-1.4176085980000002,0.776103442,1.315453593,-5.949923315,-4.545573433,-5.940417664,-8.94239341,-5.454378975,-4.866853096,-5.871575872999999,-3.341591662,-1445.8995952792466 -2217,2217,I140R,0.036711934,-0.013907277,-0.650831056,-1.725957907,-2.684032739,0.06657091400000001,0.04275538,0.030668487,0.018860243999999998,-0.020024701000000002,-0.007789853,-0.417364764,-0.8842973479999999,-1.5731587969999998,-1.8787570169999999,-2.2310656840000003,-3.136999794,1.7427628659999999,0.9015630029999999,-9.9022347,-7.218070793,-9.818572411,-14.10194305,-9.578620483,-8.793966766,-7.802581152999999,-6.534454729,-1452.3347632987425 -2218,2218,I140T,0.039628878,-0.017652796000000002,0.018942399,0.014142285,-1.5231895969999998,0.074983535,0.066847596,0.012410158999999999,-0.011487941000000002,-0.009627795,-0.025677797000000002,-0.001511886,0.039396684,0.030898991,-0.002614422,-1.33385877,-1.7125204230000002,0.7960434759999999,1.33819361,-4.633910347,-3.53565287,-4.475618301,-6.287097206,-4.54070282,-4.330480537,-4.799573036,-2.0042849069999997,-1447.1886666696519 -2219,2219,I140W,0.020466501,-0.004243987,0.006879734,-0.711455142,-1.753049544,0.079097235,0.055342815,-0.014409813,-0.09234814599999999,0.010445495,-0.018933468000000002,-0.021134384,0.034893852,-0.307455825,-1.1154544579999999,-1.9170430040000002,-1.589056084,1.3839272759999999,1.35019655,-9.60957867,-8.340267883,-8.889114082,-12.83318353,-9.056764656,-8.928563202000001,-8.834125656,-8.932049556,-1449.8089921406936 -2220,2220,I140V,0.08842957,0.014856538999999998,0.036979587,0.010552858,0.015865042,-0.008646863000000001,0.080284825,0.096574315,-0.016226868999999998,0.008047181,0.021665897000000003,0.017817158,0.056142015,-0.016995573,0.038101288999999997,0.022987293,0.00874279,1.192579612,2.685602053,-1.100670506,-0.840864609,-0.857747787,-1.795814629,-1.41168927,-0.5972362370000001,-1.429142235,0.281730067,-1459.1414559581317 -2221,2221,I140Y,0.022035722999999997,-0.035699805,-0.027948017000000002,-0.033877028999999996,-0.643092522,0.031796354,0.036691048,0.007380398000000001,0.057789968,-0.026918409,-0.044481201,-0.062293021,0.006396987,-0.029867332000000003,-0.037886726,-0.472539218,-0.8136458259999999,1.49344939,1.86400115,-7.648501627000001,-5.55498674,-6.482398567000001,-12.13531704,-6.843241226,-7.22656456,-5.783980304,-3.684561085,-1448.9616901674308 -2222,2222,G141A,-0.016246767,0.054323404000000006,0.001276377,-0.00023113099999999998,-1.755335207,0.05171659,0.0031721640000000003,-0.035665697,0.043272874,0.010986265,0.097660543,-0.023356954,0.025909707999999997,0.014275963999999999,-0.014738226,-1.643029515,-1.867640899,0.699148322,1.314624099,-7.63416008,-7.494508286,-7.834208267,-7.800629227000001,-7.39154789,-7.649906731000001,-7.25189471,-6.22765299,-1446.600393764209 -2223,2223,G141C,-0.067496499,0.076379365,-0.016970974,-0.199595243,-1.746883758,0.075836246,-0.052881607000000004,-0.08211139099999999,0.098469907,-0.006895608,0.15965433699999998,0.038043312,-0.07198525900000001,-0.01304904,-0.386141445,-1.70021054,-1.793556975,0.7293857559999999,1.3140519609999999,-9.800131223,-9.637469994,-10.18542661,-9.706120689,-9.687845917,-9.7837929,-8.582593854,-8.656845841,-1449.440744946245 -2224,2224,G141E,-0.037855371,0.030800462,-0.052099047999999995,-0.02534532,-1.398896115,0.059927142999999995,0.01474989,-0.090460631,-0.09097872800000001,0.07950887400000001,-0.01790795,-0.02823143,-0.075966666,0.045263429,-0.095954069,-1.335423007,-1.462369223,0.759389395,1.3361049170000001,-6.445106844,-6.18060688,-6.998313004,-6.175407432999999,-6.73665741,-6.1345494920000005,-6.201491466,-5.921741667999999,-1455.313364350237 -2225,2225,G141D,-0.067909527,0.023840992999999998,-0.041156918,0.017771539,-1.723675786,0.092380768,-0.063617029,-0.072202025,0.122492774,-0.019056992,0.066738977,-0.111522539,0.029208703,0.020156564,0.015386513000000001,-0.889592688,-2.557758883,0.74743775,1.374396961,-3.873250647,-3.645155693,-4.115102348,-3.3584631810000003,-4.550142311,-3.6973897019999997,-4.7276631710000006,-3.616531635,-1459.6937628071755 -2226,2226,G141F,0.040114643,0.068174543,-0.00011464799999999999,-0.9846595909999999,-2.235048401,0.050692995,0.10563984,-0.025410555,-0.027751828,-0.021762885,0.15811197,-0.010247721,0.010018426,-0.605968859,-1.3633503219999998,-1.8533805159999999,-2.616716286,1.862528639,1.472809675,-11.38295504,-10.65978058,-11.98453452,-11.06583293,-11.00121209,-12.20341511,-9.345783834,-10.56086115,-1448.373123991536 -2227,2227,G141I,-0.120222281,0.003405966,-0.0031094679999999998,-1.0250397820000001,-2.337303037,0.000638883,-0.135142129,-0.10530243199999999,-0.138450125,0.030373317,-0.023561386,0.083745405,-0.08996434,-0.305145032,-1.7449345319999998,-2.128603248,-2.546002825,1.5932854090000002,1.342960855,-9.135840883,-8.72706987,-10.40629797,-9.709876677999999,-8.356974762,-8.478985137999999,-7.45190376,-5.641960555,-1439.558489649091 -2228,2228,G141H,-0.013113225,0.03592757,0.021801546,0.038961832,-1.5860283990000001,0.123103545,0.040280937999999995,-0.066507388,0.023014483,-0.013211099999999998,0.08506624,0.004120059000000001,0.039483032,-0.005058099,0.082981762,-1.593743205,-1.578313592,0.75321606,1.320133877,-8.658708661,-8.415706467,-8.843847351,-8.626537529,-9.560872971,-7.846578987000001,-8.429084632999999,-7.998036452000001,-1458.4983334713615 -2229,2229,G141K,-0.097789617,0.075817383,-0.014428483,-0.030623595,-1.367054306,0.057337930999999995,-0.057495494,-0.13808374,-0.231871811,0.055008364000000004,0.096626401,0.08426708,-0.113124045,0.074364019,-0.135611208,-1.399489102,-1.33461951,0.443429755,1.311898188,-5.733889723,-5.6194527889999994,-5.625838402,-6.093531197000001,-6.7042877579999995,-4.62633847,-5.427061537999999,-5.181346957,-1458.3910312433727 -2230,2230,G141M,-0.046860513,0.039629861,-0.049201916,0.074906312,-1.532986606,0.016183909,-0.023508859,-0.070212167,-0.197212508,-0.034425429,0.113685151,-0.093884543,-0.004519288,0.024891897000000003,0.124920726,-1.59977517,-1.466198041,0.703867818,1.315950193,-10.55450373,-9.987561592,-11.04544693,-11.49914362,-10.07782359,-10.16254291,-8.596394802999999,-8.088402807000001,-1444.7898819157854 -2231,2231,G141L,-0.027995232999999998,0.089400842,-0.009828929,-0.164416401,-1.747878303,0.042055302999999995,0.005468728000000001,-0.061459192999999995,-0.050376448,0.050409876,0.128391808,0.000480356,-0.020138213000000002,-0.000468893,-0.328363908,-1.838945157,-1.656811448,0.8674374859999999,1.312620857,-10.11876252,-9.975550858,-10.52134386,-10.85500507,-9.790473366,-9.45143943,-8.133323921,-7.297633161,-1435.416563290637 -2232,2232,G141N,-0.069070313,0.005640695,-0.073310871,-0.158982193,-0.71373099,0.17508137199999999,-0.05054663400000001,-0.087593991,0.062424802,-0.148151688,0.159433078,-0.135881885,-0.010739857,-0.068589111,-0.249375275,-0.6749791740000001,-0.752482805,1.219871232,1.5654299980000002,-4.621586218,-4.784200836,-4.709714928,-4.649816223,-5.13473246,-3.8294666439999996,-5.102472371,-4.8906755319999995,-1457.709882854484 -2233,2233,G141Q,0.030117083,0.034721813,-0.07069142099999999,0.0028035770000000002,-1.174642188,0.081322023,0.078057512,-0.017823346,-0.10603854300000001,-0.036086213,0.105529839,-0.077061922,-0.06432092,0.03093033,-0.025323176,-1.476497217,-0.872787159,0.327345033,1.305208412,-8.104459341,-7.800983062999999,-8.03881192,-7.90984761,-8.740981842,-8.031672272,-7.645155712999999,-7.361082595,-1452.801452293992 -2234,2234,G141P,-0.053865984000000006,0.051472652,-0.018488252,-1.52972003,-2.550557496,0.040977972,-0.015435919,-0.092296049,-0.046656542999999995,0.008616366,0.094328938,-0.008498414000000001,-0.02847809,-1.290330393,-1.769109667,-2.438747657,-2.6623673340000003,0.973049756,0.7536675,-9.198641152999999,-9.502551041,-9.586049277999999,-8.821390938,-8.77016803,-9.313046478,-6.634202232000001,-3.6551321310000002,-1458.509954023175 -2235,2235,G141S,-0.034085452999999995,0.111418406,0.01903371,0.022590172000000002,-1.572262939,0.071782072,0.0004947,-0.06866560599999999,-0.061371697,0.09218046699999999,0.130656344,0.028549002,0.009518418,0.063902764,-0.01872242,-1.454797584,-1.689728294,0.5722636489999999,1.316109343,-5.90490287,-5.615930099,-6.465906853,-6.002451775,-5.627747498,-5.812478127,-5.340712795,-4.545116414,-1448.5165041368455 -2236,2236,G141R,-0.040246135,0.023015558,-0.023955762999999998,0.001517167,-1.58238244,0.060374483,-0.016239311,-0.064252958,-0.055729670999999995,0.008035801,0.037995315,-0.020418905,-0.027492621000000002,0.015766437,-0.012732103,-1.6575146440000001,-1.507250236,0.8294104390000001,1.321010994,-6.788199446,-6.569435013,-6.964848137000001,-6.730031776000001,-7.886068817000001,-5.790613487000001,-6.2486321160000005,-5.4237736739999995,-1454.613879501354 -2237,2237,G141T,-0.057877541,0.012784463000000001,-0.014771596000000001,-0.246644058,-1.95731596,0.075194375,-0.108745552,-0.00700953,0.115250909,0.021779262,0.0037896640000000003,0.0027913720000000003,-0.032334563,-0.01390963,-0.479378486,-1.7845155380000002,-2.1301163819999998,0.7738183129999999,1.310477267,-7.45193616,-6.883353996,-8.065084167,-7.564050362000001,-6.811869484,-7.935322792000001,-6.47515324,-4.615081244,-1447.8754701390862 -2238,2238,G141W,-0.022431573,0.01509296,-0.158098756,-1.542783045,-2.4720980569999997,0.11058718599999999,0.028921582,-0.073784728,-0.11802204599999999,-0.021819794,0.052005712999999995,-0.029515631,-0.286681881,-1.3098577470000001,-1.775708343,-2.514865555,-2.429330558,0.732670954,0.723729362,-10.7581419,-10.27614566,-10.90705335,-10.88416222,-11.07091641,-10.65243187,-9.328710494,-10.46766159,-1452.2758591165766 -2239,2239,G141V,-0.02126953,-0.012338416999999999,0.000246538,-0.816436534,-1.844794396,0.055715277,0.044242888,-0.086781947,-0.006767336,-0.014170364,-0.01050647,0.0030067740000000003,-0.002513698,-0.24957356,-1.3832995080000001,-2.1416985459999998,-1.547890245,1.217750144,1.305482002,-8.306577269,-7.886409218,-9.533538818,-8.706027695,-7.682543655,-7.724366959,-6.833978881,-5.109497341,-1440.7921330318786 -2240,2240,G141Y,-0.188018422,-0.021067377,0.037378392,-0.8526990870000001,-2.242010824,0.045803785,-0.172112347,-0.20392449699999998,0.19160812100000002,0.067505385,-0.109640139,0.177797352,-0.103040569,-0.09432044199999999,-1.611077731,-1.770845627,-2.71317602,0.956216725,1.3210392009999998,-10.08119046,-9.727016434,-10.88435323,-9.674218788,-10.11267155,-10.00769231,-8.459784056,-8.088402807000001,-1453.3598717504647 -2241,2241,G142A,-0.007918629,-0.034104733,-0.002959489,-0.715207921,-1.667980374,0.089995638,0.029380546,-0.045217803,0.043908665,-0.051147639,-0.017061826999999998,-0.056922065,0.051003087,-0.322812764,-1.107603077,-1.856181667,-1.479779081,1.461658809,1.370198966,-7.579718086000001,-7.250038185,-7.215907005,-8.476607567,-7.056878212000001,-7.899159462,-7.016289966,-6.273001337,-1445.246263035573 -2242,2242,G142C,-0.05076114599999999,-0.007245601,-0.11159738300000001,-1.6430326069999999,-2.370468153,0.158694287,-0.032475146,-0.069047145,-0.074871893,-0.061676275,0.047185074,-0.084060941,-0.13913382400000002,-1.20984229,-2.076222923,-1.977915264,-2.7630210410000005,2.642937279,1.8097818509999999,-11.14399873,-10.556320300000001,-11.39188991,-12.2497953,-10.29082924,-11.23115888,-9.35014905,-10.85705337,-1459.7952369092964 -2243,2243,G142E,0.012007875,-0.014425225,-0.027715574,-0.085481208,-2.143842851,0.112099512,0.068309259,-0.04429351,-0.09066616,-0.010880035,-0.017970414,-0.06635611,0.010924963000000001,-0.030128115,-0.140834301,-1.6167315009999998,-2.670954201,0.696998958,1.315006642,-7.092463037000001,-6.544968765,-6.953279297000001,-8.308854576,-6.272642464,-7.382570084,-5.989436282000001,-5.129622228000001,-1455.6937978328206 -2244,2244,G142D,-0.037139755,-0.109155751,0.045134795,0.012458292,-2.152682452,0.09106566,-0.08503543599999999,0.010755926,-0.007020396999999999,-0.015571871999999999,-0.20273963,0.066327762,0.023941827000000002,0.03816853,-0.013251946,-1.486625053,-2.818739851,0.48206122100000004,1.311838495,-6.245531575,-5.369806404,-6.866564147999999,-7.200748276000001,-5.248547112,-6.5419919360000005,-5.484147509,-4.88865803,-1446.3812895850278 -2245,2245,G142F,-0.082525868,-0.035119733,-0.958413948,-2.472575911,-2.427977434,0.099356751,-0.063602613,-0.101449123,-0.018218296999999998,0.0503695,-0.120608966,-0.9076478640000001,-1.0091800309999999,-2.231796866,-2.713354955,-2.300899835,-2.555055032,1.8065285519999998,0.637570166,-12.24491685,-11.85713472,-12.66633073,-13.2394419,-11.29817021,-12.16350668,-9.35014905,-10.85705337,-1465.9993651751429 -2246,2246,G142I,-0.10273421699999999,-0.46508131700000005,-1.611331635,-2.428267757,-2.534184278,0.159800889,-0.091684495,-0.113783939,-0.06743631900000001,-0.096227804,-0.833934829,-1.906422773,-1.316240496,-2.151390529,-2.705144984,-2.220493498,-2.847875058,1.063628505,-0.047296183,-10.93169438,-10.74536913,-11.27484601,-12.045190400000001,-9.954308722999999,-10.63875763,-8.187650882,-7.776074977,-1459.286672563292 -2247,2247,G142H,-0.054401575,-0.059377642,-0.045429303,-0.259108989,-1.944233898,0.11279848599999999,-0.040246866,-0.068556283,-0.018091476999999998,0.000480126,-0.11923541,-0.029728927000000002,-0.061129679000000006,-0.115506175,-0.402711803,-1.938192203,-1.9502755930000002,0.908050571,1.307603874,-10.36928284,-9.757443161,-10.28605537,-11.68717229,-9.28362014,-10.83212322,-8.299737207,-7.776074977,-1464.0602263743058 -2248,2248,G142K,-0.03161511,-0.083270858,-0.04902908,-1.341900506,-2.514586481,0.076451929,-0.00779972,-0.055430499,-0.075740482,-0.035235427,-0.13130628800000002,-0.038660747999999995,-0.059397412000000004,-1.094572268,-1.589228743,-2.394124159,-2.635048803,0.83963527,0.7556811040000001,-8.662540465,-8.57718589,-7.853943954,-10.21513865,-7.737710967999999,-8.928722862,-6.729698685,-5.453153235,-1455.1717430474237 -2249,2249,G142M,0.005580048000000001,0.054615437999999995,-0.303590933,-2.10269055,-2.631156092,0.043107993,0.005083008,0.006077086999999999,-0.092428006,0.11277675300000001,-0.0035458779999999997,-0.146566145,-0.46061572100000003,-1.438530464,-2.766850636,-2.352731473,-2.90958071,0.8355971879999999,0.7172787420000001,-11.93969234,-11.69991994,-11.79995271,-13.23932696,-10.99054937,-11.9687127,-9.35014905,-10.85705337,-1464.6901940149255 -2250,2250,G142L,0.013551728,-0.066283454,-1.275378814,-2.340673341,-3.0035615389999997,0.160271423,0.055107092,-0.028003636000000002,0.001471171,-0.07282936799999999,-0.059737539000000006,-1.1680999859999999,-1.382657641,-2.492248988,-2.189097694,-2.561351957,-3.44577112,0.832023822,0.10881502400000001,-12.05666346,-11.93597468,-11.94419077,-13.28638593,-11.26310127,-11.85366464,-9.35014905,-10.85705337,-1459.4443866135553 -2251,2251,G142N,-0.0061224109999999995,0.004108888,-0.01963966,-0.014689238,-1.272083085,0.071778185,0.027970857000000002,-0.040215678,-0.04624702,0.005672825,0.002544951,0.011087225,-0.050366545,0.04403601,-0.073414486,-1.403883996,-1.140282174,0.5555748979999999,1.3170926170000001,-7.799908798,-6.684626297,-8.532624069,-8.882508162999999,-6.834601784,-8.065183678,-6.260274544,-5.728460279,-1454.5751164215617 -2252,2252,G142Q,-0.011588764,0.005714159,0.031628617000000005,-1.0193870870000001,-2.542831659,0.096821321,0.003752035,-0.026929562999999997,0.011248873000000001,-0.021372218999999998,0.032800537000000005,0.024130082,0.039127151,-0.424004211,-1.6147699619999998,-2.072890777,-3.0127725410000004,1.5475342330000001,1.347991989,-10.66898906,-10.83950645,-10.11730492,-11.7958629,-9.712838745,-10.879432300000001,-8.451543846,-7.776074977,-1460.5991744319908 -2253,2253,G142P,-0.053400637,-0.047392434000000004,-1.203563266,-2.132097089,-3.086825287,0.102056342,-0.0234348,-0.083366473,-0.004681594,-0.033249783,-0.061535085,-0.857623687,-1.549502845,-1.8858823340000002,-2.378311843,-2.8223597380000003,-3.3512908360000004,2.136914817,0.9307250859999999,-9.270669031,-8.431125984,-10.23634682,-10.26241149,-8.062073753,-9.3613871,-7.242511502,-6.68569624,-1464.1696689608507 -2254,2254,G142S,-0.038780581,-0.01984802,-0.016873593,-0.009595066999999999,-1.686527285,0.09836341400000001,-0.01963263,-0.057928532000000005,-0.030830386,-0.014612635,-0.025083404,-0.038303451,0.004556266,-0.000848861,-0.018341272,-1.4120018859999999,-1.961052684,0.593721961,1.320521467,-6.15184527,-5.446897148,-6.31739399,-7.264205231,-5.417370002999999,-6.313359977999999,-5.185022817,-4.672779996,-1446.1795348771848 -2255,2255,G142R,-0.042044818,-0.029193134,-0.035561606,-1.491082415,-2.438075268,0.069216978,-0.007940768,-0.076148867,0.011136638,-0.0020858260000000003,-0.056300442,-0.031385962999999996,-0.039737249,-1.252493095,-1.729671734,-2.3768651530000002,-2.499285382,1.008565821,0.762265709,-9.681279542999999,-9.632399742,-9.236397751,-10.874023900000001,-8.477773209,-10.18580311,-7.15470692,-6.5316833039999995,-1454.3486052621156 -2256,2256,G142T,-0.08765397,-0.07165683099999999,-0.013367515,-0.074748106,-1.6018280040000001,0.111027755,-0.068567322,-0.10674061800000001,-0.012898788000000001,-0.040050045,-0.103263616,-0.045697176,0.018962147,-0.019823416,-0.129672795,-1.799889505,-1.4037665030000002,0.739051439,1.308293851,-8.102403844,-7.27952729,-8.014841629,-9.354381737,-7.246785407999999,-8.616483153999999,-6.216721832,-4.788835843999999,-1448.3293401636183 -2257,2257,G142W,-0.06294942099999999,-0.36454670200000006,-1.7473316000000003,-2.175192098,-2.130593621,0.104795789,-0.016733208,-0.109165634,-0.005952425999999999,-0.047098389000000004,-0.681995015,-1.566934525,-1.927728675,-1.8119022809999998,-2.538481914,-1.881005251,-2.3801819909999997,4.298332589,2.744826203,-11.87994325,-11.26590637,-12.06705408,-13.06177983,-10.99859278,-12.00638319,-9.35014905,-10.85705337,-1463.3171485601924 -2258,2258,G142V,-0.006941747,-0.016901748,-1.276927455,-1.645767758,-2.534903025,0.147832321,0.030199741000000002,-0.044083234000000006,-0.062214279000000004,-0.025552091000000002,-0.008251405,-1.234406695,-1.3194482140000001,-1.86934553,-1.422189985,-2.28087118,-2.7889348689999998,3.12628629,1.659614709,-11.27875356,-11.13592869,-11.48950177,-12.25602251,-10.30334683,-11.20896797,-9.00978811,-9.245398002,-1454.7060600621626 -2259,2259,G142Y,-0.020395846999999998,-0.002859913,-0.7332440309999999,-1.490110227,-2.7861323689999997,0.164849824,0.021503826,-0.06229552,-0.010708695,-0.005827259,0.000107434,-0.380377832,-1.086110229,-1.470443629,-1.509776824,-2.5395465980000003,-3.032718139,1.6513083780000002,0.892491075,-12.44201434,-12.06116125,-13.11235645,-13.07172317,-11.32951818,-12.63531265,-9.35014905,-10.85705337,-1465.3195777223445 -2260,2260,P143A,-0.027449547999999997,0.025518747,-0.017848951000000002,-0.028073294,-1.1555619320000001,0.035648082000000005,-0.005749587,-0.049149508,-0.0059857669999999995,-0.000451576,0.05148907,-0.003798981,-0.031898921000000004,-0.033611351,-0.022535237000000003,-1.146633414,-1.164490449,0.6661265989999999,1.339838995,-6.53739415,-6.038025833,-8.748475716,-6.50633815,-5.332448563,-6.061682487000001,-6.365702676000001,-2.40374905,-1447.6810263488442 -2261,2261,P143C,-0.059361146,0.008437733000000001,-0.00646229,-0.019434292,-1.774256601,0.036847143,-0.048344839,-0.07037745200000001,0.012166999,-0.017189342,0.034064807,0.032404517,-0.045329096,0.003022429,-0.041891012000000005,-1.374011993,-2.174501208,0.6859922909999999,1.327010499,-12.01055073,-12.29039792,-14.56644402,-11.07285207,-10.6918622,-11.43119746,-10.06511847,-6.849734047,-1444.2375358031131 -2262,2262,P143E,-0.040004756,0.025175263,-0.046077083,-0.579766279,-2.245986947,0.040978127,0.009048587,-0.089058098,0.065299361,0.007843421,0.042507105,-0.027322772999999998,-0.064831392,-0.219952896,-0.9395796609999999,-1.941145341,-2.550828553,1.24732889,1.33097985,-11.12599111,-10.798226699999999,-13.49302814,-10.3230258,-9.620823913999999,-11.39485101,-8.386506725,-3.99851794,-1450.4539819019847 -2263,2263,P143D,-0.060209362999999995,0.047597100999999996,-0.325704275,-1.95852858,-2.9881581539999997,0.006362817,-0.066033185,-0.05438554,-0.059639375,0.033937607,0.061256595,-0.164084507,-0.487324042,-1.496003241,-2.421053919,-2.77687708,-3.199439228,1.264451243,0.775584791,-12.65392538,-12.60947099,-15.71249095,-11.88202493,-10.35736584,-12.70827422,-9.123094562999999,-4.671164283,-1445.1272511766292 -2264,2264,P143G,-0.00139505,0.050165626,-0.019464478,-0.035218314,-1.833277047,0.003680445,0.015694003,-0.018484102,-0.042035486,0.0048618279999999995,0.09546942300000001,-0.034042914,-0.004886041,0.0017824170000000001,-0.07221904400000001,-1.6107983540000002,-2.055755739,0.6504015360000001,1.312397861,-9.519024211,-8.963970726,-12.34241113,-8.479893959,-9.463693588,-8.345151649,-7.6389238420000005,-2.9153602910000003,-1440.3902793661691 -2265,2265,P143F,-0.049734357,0.015532533000000001,-0.037831506,-0.930476462,-2.387195776,0.017569422,-0.024534082000000002,-0.074934632,-0.093080096,-0.019773844,0.050838909,-0.00042062400000000003,-0.07524238700000001,-0.35761594799999996,-1.503336976,-2.075843915,-2.698547637,1.551706052,1.345293151,-12.0926022,-15.07377172,-14.89256205,-9.611927055,-9.659302109,-11.22544806,-8.343966882,-3.131284202,-1447.4905161252245 -2266,2266,P143I,-0.12472323699999999,0.022631218999999998,-0.06551781,-0.22808325699999998,-2.005215035,-0.009572492,-0.063933646,-0.185512827,-0.061946442000000004,0.043551648,0.0017107889999999999,0.001122164,-0.132157783,-0.088948189,-0.367218324,-1.822119698,-2.1883103719999997,0.961765723,1.318747064,-8.517390579,-10.08056106,-11.37134324,-7.456979057000001,-5.98103772,-7.6970318220000005,-5.676446916000001,-2.20098652,-1445.5975952711888 -2267,2267,P143H,-0.01400415,-0.060021736,-0.065957663,-0.063149184,-0.6523088920000001,-0.012056058,-0.022413492,-0.005594808000000001,-0.013609597,-0.025324008999999998,-0.09471946199999999,-0.058919333,-0.072995992,-0.039095221,-0.087203147,-0.579309619,-0.725308165,1.234363111,1.6253157630000001,-13.04623011,-13.368855199999999,-16.07421033,-10.91184659,-11.04256599,-13.83367247,-9.074199408,-5.571040707000001,-1447.282329031732 -2268,2268,P143K,-0.023671493,-0.011107724,-0.09688148,-1.622279905,-2.718579118,0.048967530999999995,0.034438626,-0.08178161099999999,0.023904781,-0.09372256300000001,0.071507115,-0.09016361099999999,-0.10359934800000001,-1.401993487,-1.8425663230000002,-2.162994091,-3.274164145,1.012579794,0.7463549820000001,-11.46886972,-12.29676807,-14.53057054,-9.349727698999999,-9.556155525,-11.61112675,-7.934823852,-3.162355406,-1449.817203884013 -2269,2269,P143M,-0.028300197000000003,0.019771131,0.028614413999999998,-0.865263771,-2.50650652,-0.051351500999999994,0.041746234,-0.09834662699999999,-0.136148448,-0.017261789,0.05680405,0.012467398000000001,0.04476143,-0.500198509,-1.230329032,-2.24673398,-2.76627906,1.6812704680000001,1.345340835,-10.91956935,-12.4040781,-13.57858528,-9.827217285,-9.860710327,-8.92725576,-8.005466323,-2.086890233,-1448.8414619872347 -2270,2270,P143L,-0.069901857,0.016946881,-0.019754515,-0.973330075,-1.965140669,0.032872637,-0.040426506,-0.099377207,-0.001331792,0.012080200000000001,0.021813562,0.000767597,-0.040276626,-0.459567137,-1.4870930130000002,-1.5450654730000002,-2.385215864,1.835056517,1.561962605,-8.978137535,-11.87773618,-10.60471458,-7.919180016,-6.610610877999999,-7.87844603,-7.157352134,-1.754621274,-1446.8016179194674 -2271,2271,P143N,-0.047994887,0.022793876,-0.02139908,-0.757630274,-1.942733992,0.029940152,-0.029506526,-0.066483248,-0.054393304,0.006904405,0.038683347,-0.026017367000000003,-0.016780792,-0.288605328,-1.22665522,-1.9420843559999998,-1.9433836269999998,1.33580458,1.341437604,-12.22861652,-12.28358269,-15.29183935,-11.12916464,-10.50826353,-11.93023238,-9.513602443,-5.964658021,-1440.7674669623375 -2272,2272,P143Q,-0.033764503,0.067979289,0.012350669,0.012693448000000001,-1.2699222540000001,0.02447694,0.028745075,-0.096274081,-0.051621792,0.053803524000000005,0.08215505299999999,0.049616892999999995,-0.024915556000000002,0.086557229,-0.061170333,-1.119379945,-1.4204645619999998,0.453999266,1.3242181259999999,-11.51428711,-12.45492176,-13.73444318,-10.09584335,-9.589359459,-11.69686783,-8.094200721,-4.14833374,-1450.4772918401286 -2273,2273,P143S,-0.054796433,0.001417655,-0.014364027,-0.021803705,-1.6966460890000001,0.009052072,-0.03571065,-0.073882215,-0.025774752,0.018070564,-0.015235253999999998,-0.004460602,-0.024267451000000002,0.036599037,-0.080206446,-1.6109571169999999,-1.782335061,0.514476698,1.306907684,-7.742215562,-6.923545562999999,-9.644116713999999,-7.500043251,-6.9928632660000005,-7.650509017999999,-7.631680547999999,-4.7312467730000005,-1441.0461475951597 -2274,2274,P143R,-0.04389502,0.01665216,-0.15671147300000002,-1.443419754,-2.376351269,0.072213813,-0.010187705,-0.07760233400000001,-0.021634924,-0.044471102,0.077775422,-0.08832319699999999,-0.225099749,-1.280221379,-1.606618128,-1.7761045430000002,-2.9765979939999996,3.573738718,2.7135467610000004,-10.99257254,-12.00351657,-13.73030212,-8.860979362,-8.760707184,-11.60735744,-7.628152817999999,-3.512597695,-1443.4573226980865 -2275,2275,P143T,-0.017624823,0.057412229,0.010783477,0.001014245,-1.151452176,0.06747499400000001,0.010002722,-0.045252367,0.00367954,0.066514693,0.048309764000000005,0.043518243,-0.021951289,0.052567164000000006,-0.050538675,-1.020670119,-1.282234232,0.581681915,1.340959376,-6.191726691,-6.04389904,-8.428460068,-5.909918976,-4.912681175,-5.6636741939999995,-6.507101136,-2.31663867,-1444.256979169324 -2276,2276,P143W,-0.0006648139999999999,0.045913962999999995,-0.613228645,-2.109361463,-3.021949433,0.033801728999999996,0.069815221,-0.071144848,0.011684896,-0.034468899,0.126296824,-0.307006702,-0.919450587,-1.477685999,-2.741036926,-2.7005678910000004,-3.343330975,1.5436015269999999,0.850944875,-12.94510947,-12.75166636,-16.18462139,-11.21995959,-11.28570535,-13.28359467,-9.033611025,-5.269048819,-1445.0701124127954 -2277,2277,P143V,-0.013427063999999999,0.047426811,-0.025616377000000003,-0.041868353,-1.539005603,0.025029682999999997,0.015545993999999999,-0.042400121,-0.022800205,-0.000169072,0.095022694,-0.033473897,-0.017758857,-0.038131522,-0.045605183,-1.560934099,-1.517077106,0.9227773000000001,1.334189947,-7.760243381,-8.611276825,-10.87627431,-6.51744294,-5.406311516000001,-7.389911316,-5.808696795,-2.55664857,-1444.558779832907 -2278,2278,P143Y,-0.083510742,0.037057951,-0.071059861,-2.117514864,-2.758068812,0.0720154,-0.06142178400000001,-0.105599699,-0.018278327,0.008108923,0.066006978,-0.04153321,-0.10058651199999999,-1.486991221,-2.7480385060000003,-2.165805068,-3.350332555,1.075878807,0.7328546109999999,-12.89427005,-14.68626721,-16.16381075,-9.996887955,-10.09441668,-13.52996767,-7.762556547000001,-4.307385026,-1447.9816095931455 -2279,2279,K144A,-0.006117771,-0.080593749,0.002331417,-0.009388397,-0.072388927,0.048290677000000004,0.01476768,-0.027003221,0.010292264,-0.079850648,-0.08133685,-0.040938787000000004,0.045601620999999995,-0.027326684,0.00854989,-0.062482442,-0.082295411,1.356455985,2.37120265,0.302930457,0.275363205,-0.39577549,0.77296669,0.512806564,0.349291313,-2.209876447,0.9549755320000001,-1461.6088997209445 -2280,2280,K144C,-0.045242494,-0.068711581,-0.01396067,-0.033098357,-0.17192907899999998,0.105578579,7.77e-05,-0.090562688,-0.012907638,-0.072455965,-0.064967197,-0.022636732000000003,-0.005284606999999999,0.0030154820000000003,-0.069212195,-0.145069305,-0.198788852,1.250716872,2.12455322,-5.7679525279999995,-5.110060425,-6.708175957000001,-5.978851822,-5.5273623810000005,-5.515312057999999,-7.908438113,-5.478130544,-1459.0023385002278 -2281,2281,K144E,0.001336261,-0.025060048999999997,-0.002331254,-0.015830223,-0.022203867000000002,0.003069423,0.041253265,-0.038580744,-0.016028753,-0.057707469000000004,0.007587371,-0.019412481000000002,0.014749973999999999,-0.007947353,-0.023713092999999998,-0.058864047,0.014456313,1.3962876,2.5036407000000005,0.6334934489999999,0.385567764,0.397957436,1.121579803,0.950045395,0.312316849,-2.600582312,0.870753971,-1461.1887028380297 -2282,2282,K144D,-0.076503938,-0.08135228900000001,-0.013722558999999999,-0.064692552,-0.055729847,0.092765002,-0.02683749,-0.126170386,0.004756833,-0.110774891,-0.051929687,-0.06430178,0.036856663,-0.024633686000000002,-0.104751417,-0.09238693699999999,-0.019072757,1.36285572,2.2951806809999997,-1.837801918,-1.7914201969999999,-3.1419546130000002,-0.318335037,-2.514191109,-1.423108635,-4.601068156,0.722602588,-1456.8478895467706 -2283,2283,K144G,-0.016011456,-0.042885912000000005,-0.006566879,-0.017222104,-0.020137481999999998,0.023783593,-0.003259748,-0.028763162999999998,0.013208295,-0.070958004,-0.01481382,-0.046260129000000004,0.033126371,-0.018489068,-0.015955139,-0.04639569,0.006120726999999999,1.31870905,2.431119397,-2.5649941640000002,-2.284029167,-4.277086945,-1.9139443740000002,-2.125563316,-2.224347015,-4.411702013,-0.527993782,-1456.183328170795 -2284,2284,K144F,0.048200585,0.009135824,0.042906682,-0.00583436,-0.074061544,0.014287563999999999,0.057242352999999996,0.039158816,0.079987625,-0.038672889,0.056944536,-0.054156317999999995,0.13996968199999998,-0.04219065,0.030521931000000002,-0.098231745,-0.049891343,1.372849976,2.309139269,-5.085984941,-3.649625038,-6.715675591,-5.442262283,-4.9485835719999995,-4.673778221,-6.913211511,-4.194719319,-1458.1255413494073 -2285,2285,K144I,-0.014477304,0.003957895,-0.0095023,0.065604517,0.047126188,-0.025531257999999998,0.015414862,-0.044369469,-0.052958175,0.040586383,-0.032670594,0.031405969,-0.050410569,0.147072839,-0.015863806,0.001833794,0.092418581,1.137271404,2.68373177,-3.847411601,-2.0893127369999998,-4.874347984,-3.8967623139999996,-4.432372147,-3.944262825,-6.4166599479999995,-3.406380153,-1459.0360468514264 -2286,2286,K144H,-0.031426317999999995,-0.007453538000000001,0.048767436,0.031028704,-0.009511754,0.09816811199999999,0.019629486,-0.08248212099999999,-0.032233212000000004,0.034617614,-0.04952469,0.04702390099999999,0.05051097,0.048289639,0.013767769,0.023878148999999998,-0.042901655999999996,1.124699656,2.582810921,-3.2945932389999997,-2.369472504,-4.827764923,-3.2566109310000004,-2.966116379,-3.0530014569999997,-4.91540279,-2.635765889,-1458.0781291984022 -2287,2287,K144M,-0.030677691,-0.052012224,-0.036494797999999995,-0.046657784,-0.076435888,0.033177188999999996,0.009756144,-0.071111525,-0.000786915,-0.101875003,-0.002149445,-0.100676494,0.027686897999999998,-0.06416028900000001,-0.029155279,-0.121309766,-0.031562009,1.494608538,2.298426105,-3.756495451,-2.791544212,-4.906698021,-3.52389724,-4.072224609,-3.488113174,-5.781763947999999,-3.579595325,-1455.7193159447052 -2288,2288,K144L,-0.028383135,-0.068444093,-0.014159005,-0.023360785,-0.083766349,0.032343275,-0.005900178000000001,-0.050866090999999995,0.027364957999999998,-0.051738965,-0.085149221,-0.023832264,-0.004485745,-0.002449079,-0.044272491,-0.075705196,-0.09182750099999999,1.351470762,2.3553165430000003,-3.180989313,-2.005607544,-4.206407318,-3.396513557,-3.3365633619999997,-2.959854782,-5.4632451060000005,-2.810241832,-1455.0282868328504 -2289,2289,K144N,-0.030653457999999998,-0.019735421,0.019137653,-0.018144852,-0.004878996,0.036265724,-0.009139058,-0.052167858,0.025501781,-0.009102675,-0.030368166000000002,-0.002556184,0.04083149,0.007129481,-0.043419184000000006,0.033103296000000004,-0.042861287000000005,1.146717002,2.694846918,-2.6895999710000003,-2.497229416,-3.908333771,-2.2670781019999997,-2.420422813,-2.354935753,-4.6225795,-1.253847636,-1459.5960737625137 -2290,2290,K144Q,-0.015007248,-0.044765932,0.006803765,0.0034771309999999996,-0.012246845,0.057304697,0.011979674,-0.04199417,0.080263362,-0.069327262,-0.020204602,-0.000288323,0.013895853,-0.037923441,0.044877703,-0.033730776000000004,0.009237086,1.277769363,2.4540059640000003,1.1941698790000002,1.315619934,1.224047997,1.108029457,1.537407219,0.7857447890000001,-2.057751389,-0.10223279099999999,-1459.3346680901013 -2291,2291,K144P,-0.056837282,-0.103395044,-0.021428383,-0.039765344,-0.127841549,0.08336550200000001,-0.035530576,-0.078143987,0.012711667,-0.06302067900000001,-0.14376940900000001,-0.051519502,0.008662737,-0.022853326,-0.056677360999999996,-0.10377577,-0.15190732699999998,1.502683455,2.427753997,-1.937269453,-1.436102142,-3.0228598860000004,-1.289556236,-2.156744995,-1.7810840069999998,-3.631408579,-0.510029683,-1453.2922492953949 -2292,2292,K144S,-0.049289785,-0.08164013,0.011166371999999999,-0.025468378,-0.054032555999999995,0.064306298,-0.013642208999999999,-0.08493736,0.013471641999999999,-0.060438320999999996,-0.10284193800000001,-0.009987288,0.032320032,-0.021798819,-0.029137936,-0.043647131,-0.06441798,1.299251671,2.391722178,-0.382830165,-0.408854431,-0.339947189,-0.557738159,0.0007668760000000001,-0.6083779220000001,-2.560178641,-0.358870387,-1456.9082679394633 -2293,2293,K144R,-0.057966532,-0.112444244,-0.010584129,-0.035538135,-0.08119536299999999,0.055999597000000005,-0.038576068,-0.077356995,0.00011535899999999999,-0.091841547,-0.133046941,-0.052569125,0.031400868,-0.026521241,-0.044555029,-0.061275555,-0.10111517,1.200807553,2.262246452,-1.984859116,-1.5662122040000002,-3.576941986,-1.5741716540000001,-1.5692630840000001,-1.63770665,-4.540416486,-1.07919313,-1454.2362404237501 -2294,2294,K144T,-0.031893651,-0.078255985,0.018076231,-0.034641512,-0.074526532,0.045888701,-0.0031472740000000003,-0.060640027,0.005554747,-0.039030326000000004,-0.11748164300000001,0.010727647,0.025424814,0.011412463000000001,-0.080695486,-0.022870337,-0.126182727,1.266983826,2.5937999080000003,-1.595598286,-1.0801063,-1.929799835,-1.068138802,-2.1464048,-1.753541695,-3.531766616,-0.593603585,-1461.0334975132719 -2295,2295,K144W,-0.017560163,-0.05158539,0.019913603000000002,-0.002688137,-0.261537109,0.067386068,0.035637531,-0.070757856,0.051007998,-0.071731501,-0.031439279,-0.025920223,0.065747428,0.007343121,-0.012719395,-0.24025080899999998,-0.282823408,1.28184705,1.934994197,-6.73066387,-5.641495476,-8.407188049,-6.820401855,-6.437429665,-6.346804306,-8.812428334,-7.8557801110000005,-1462.4078240492381 -2296,2296,K144V,0.034359195,-0.024476558,0.004586651,-0.016167922,-0.046394863,-0.004641254,0.05299052,0.01572787,0.057371519,-0.065426236,0.01647312,-0.040672076,0.049845377999999996,-0.029807822999999997,-0.00252802,-0.10147134,0.008681615,1.237718668,2.1920717869999997,-2.539870451,-1.3944380719999998,-3.4182008739999996,-2.235449615,-2.862221313,-2.7890423810000002,-4.97990092,-2.456621448,-1459.7467342833988 -2297,2297,K144Y,-0.048801954,-0.065310692,0.012981718,-0.084173709,-0.17401648399999997,0.074583821,-0.016132627,-0.08147128,0.014396316999999999,-0.065327515,-0.065293868,-0.053411956,0.079375392,-0.06588665099999999,-0.102460767,-0.126025356,-0.222007612,1.528177275,2.337570839,-5.643091803,-3.905824646,-7.693876381,-5.947505211,-5.3702015229999995,-5.298051254,-7.23729785,-4.716147851000001,-1460.0758849689737 -2298,2298,E145A,0.022845756000000002,0.00631522,-0.014641312,-0.021954262999999998,-0.027764072999999997,-0.072845512,0.00301391,0.042677602,0.011867588,0.004105509,0.008524931,-0.056584034000000005,0.02730141,-0.032374579,-0.011533946000000002,-0.041875897999999995,-0.013652248,1.468686135,2.631213339,1.7433922419999999,1.2191588290000002,1.93155175,2.178545311,0.803248238,2.584457085,-1.793517546,1.799167409,-1469.0642577535473 -2299,2299,E145C,0.043467187000000004,0.082231826,0.018240006,0.019472262,-0.054622107,-0.027692176000000002,0.037572702,0.049361670999999996,-0.03699381,0.118358578,0.046105072999999996,-0.017136698,0.053616709000000005,0.014530995,0.024413529,-0.092053977,-0.017190236,1.416405485,2.403274077,-5.778317261000001,-6.809432465,-5.853200622999999,-5.216282837,-6.457572272999999,-4.555098106,-7.688842471,-3.908355492,-1472.213384736795 -2300,2300,E145D,-0.011863651999999999,0.030829767999999997,0.023021358,-0.032399874,-0.053888557999999996,-0.011271006,-0.031593849,0.007866546,-0.146170616,0.00697162,0.054687915,0.038113804,0.007928912,-0.004163785,-0.060635963,-0.08184361700000001,-0.025933498,1.250022999,2.3243472769999998,-3.3299683030000002,-3.5169245910000004,-4.392891373,-2.730646118,-3.527546135,-2.481833298,-5.350867019,-1.552260371,-1456.0879767541774 -2301,2301,E145G,0.000818953,0.031151365,0.018635137,0.013202008000000001,-0.009259429,-0.10308789199999999,-0.01312609,0.014763995,0.025350836,0.035416637,0.026886093,0.008385102,0.028885171,0.005678826999999999,0.020725188000000002,-0.02882837,0.010309512,1.3185494009999998,2.548144504,2.634117546,2.34168972,2.476275658,3.3534856719999997,2.0925282590000003,2.906608421,-1.5561279959999998,1.154514236,-1469.933313857764 -2302,2302,E145F,0.03877373,0.069160796,0.019534863,0.036830788999999996,-0.010103721,-0.06150710400000001,0.014220781000000002,0.063326679,0.022808292,0.052346915,0.085974677,-0.02398782,0.06305754599999999,0.020663625,0.052997952,-0.072582235,0.052374794,1.312338293,2.412514195,-5.493358242999999,-6.379035995,-5.167361389,-4.520440445,-6.93263578,-4.467317604,-6.845080586,-2.246614135,-1471.3678406300023 -2303,2303,E145I,0.021632242000000003,0.034570276000000004,-0.016591138000000002,0.011127513,-0.19679012899999998,0.038924162000000005,0.070113745,-0.026849262000000002,-0.148262165,-0.025634284,0.094774836,-0.07669793700000001,0.043515661,-0.019205137,0.041460162,-0.193206143,-0.200374114,1.2020937809999999,1.946879852,-4.712768831,-5.146645027,-4.633297913,-4.058873802,-5.5728279039999995,-4.152199509,-7.144536454,-2.4096818669999998,-1462.8907217094675 -2304,2304,E145H,-0.081839461,-0.015559261999999999,-0.012826337,-0.0243495,-0.07193353799999999,-0.04285923,-0.110413045,-0.053265877,-0.03775049,0.027355769,-0.058474293,0.017281234,-0.042933908,-0.005250541,-0.043448457999999995,-0.031907606,-0.11195947,1.297238333,2.549696033,-5.29394483,-6.477287673999999,-4.7818944089999995,-5.255828835,-4.9160555189999995,-5.038657715,-6.108466924,-1.841764068,-1474.2543857390992 -2305,2305,E145K,-0.076558844,0.005615403000000001,0.024360251,0.032623615,-0.034367585,-0.045516645999999994,-0.07469349900000001,-0.07842418799999999,-0.077175263,0.147030106,-0.13579929999999998,0.090773337,-0.042052835999999996,0.048846525999999994,0.016400703,-0.0034291309999999998,-0.06530603900000001,1.361033919,2.7995177910000004,-0.338064066,0.078408905,-0.669888405,-0.762160133,-0.153487297,-0.183193398,-3.028864711,0.12419799699999999,-1458.7681789039634 -2306,2306,E145M,0.032224465,0.015993195,0.046906279,-0.0054855680000000006,0.002160508,-0.008474213000000001,0.024539803,0.039909126,-0.05597384,0.012988382,0.018998008,-0.012795048,0.106607606,0.01731673,-0.028287865,-0.026224172999999996,0.030545187999999997,1.190436872,2.4920165659999998,-4.606095792,-5.389888954,-4.216062058,-4.325534248,-4.827102936,-4.271890762,-6.428849548,-2.8747289510000003,-1465.1915380419232 -2307,2307,E145L,-0.017335511,0.006945560999999999,0.000790482,-0.021533885,-0.185923179,-0.07039387,-0.029855599,-0.004815422,-0.024955127,0.032140685,-0.018249563,-0.014012877,0.01559384,0.005627558,-0.048695327999999996,-0.148991867,-0.22285449100000002,1.493747231,2.3264306169999998,-4.650396411,-5.269429222,-4.976234077,-4.58054007,-4.460128212,-3.965650475,-6.532051257000001,-2.52470143,-1462.6912926486693 -2308,2308,E145N,-0.056568785999999996,-0.009446366999999999,0.015387708,-0.02253726,-0.082234238,-0.034583653,-0.10502145800000001,-0.008116114,-0.05015271599999999,0.015861247,-0.034753981,0.02740289,0.003372525,-0.042587997999999995,-0.0024865210000000002,-0.053768946,-0.11069953,1.272643205,2.332220377,-2.90443363,-3.57780265,-3.186611473,-3.0464258039999996,-2.825981415,-1.885346809,-6.157731432,0.23478760899999998,-1465.0181637001224 -2309,2309,E145Q,0.014477441,0.022088366,0.047769373,0.028610389,-0.051717017000000004,-0.100241434,-0.03239694,0.061351822,0.009325957,0.016754201,0.027422531,-0.004083413,0.099622159,-0.009399914,0.066620692,-0.044963812,-0.058470220999999996,1.270198658,2.429479188,-0.98067986,-0.946041107,-1.281467972,-1.17690081,-0.380323746,-1.118665665,-4.348638757,-0.660509924,-1463.5586823448539 -2310,2310,E145P,-0.015483133999999999,0.028818318,0.001621454,-0.026806884,-0.36504550799999996,-0.017538035,-0.040944601000000004,0.009978333,-0.002220481,0.026975582999999997,0.030661052999999997,-0.025761432,0.02900434,-0.006848993,-0.046764775,-0.291053381,-0.439037635,1.019048146,1.703051022,-3.6338646910000003,-4.9160649030000005,-3.2990614239999996,-3.2222005080000002,-4.196377411,-2.535619209,-6.203360854,-1.76662898,-1462.693810340017 -2311,2311,E145S,0.015603816999999999,0.009995098000000001,0.020813252,-0.007909723,-0.019853986,-0.072531346,0.002118512,0.029089121000000003,-0.02810294,0.052861026,-0.032870831,0.005595475,0.036031029,-0.022708867,0.006889421999999999,-0.018305093,-0.021402877999999997,1.489016835,2.794626567,-0.742267497,-1.805109505,-0.244460335,-0.446374527,-0.928086327,-0.287306793,-4.218926581,-0.310399684,-1462.259899401106 -2312,2312,E145R,0.0076392790000000006,-0.008101718,0.025245251,0.015498078,-0.086826265,-0.055318108,-0.007191362,0.022469918999999998,0.002341216,0.049697989000000005,-0.065901424,0.014269956,0.036220545,0.007358027,0.023638129,-0.058703062,-0.11494946800000001,1.1596874259999999,2.3158833480000003,-2.366750713,-3.176674179,-2.7129398960000004,-2.146143425,-2.013504623,-1.78449144,-5.172789439,0.14726409099999999,-1453.4518258846365 -2313,2313,E145T,-0.014741609,0.00017491299999999998,-0.02332578,-0.015505611,-0.100024051,-0.07175675,-0.061533878,0.032050661,-0.011991799999999999,0.024140832999999997,-0.023791007000000003,-0.005827771999999999,-0.040823787,-0.014919923,-0.016091299,-0.10348081099999999,-0.096567291,1.39301399,2.288843354,-2.057515475,-2.9677396239999996,-1.34069529,-1.935306236,-2.4962191540000003,-1.547617073,-5.2973734619999995,-0.152210339,-1464.1644933223724 -2314,2314,E145W,-0.012279911999999999,-0.002168963,0.031635458,-0.010807998999999999,-0.182909331,-0.048243590999999995,-0.00414354,-0.020416284,-0.00011206200000000001,0.052168492000000004,-0.056506417999999996,0.03562338,0.027647536,0.028229485,-0.049845482999999996,-0.124774015,-0.241044646,1.306080109,2.198350787,-7.723893787000001,-8.40468222,-7.670265808,-7.175258827,-8.348087036,-7.021175041,-8.733595714,-5.269939067,-1476.2028176826425 -2315,2315,E145V,0.002117856,-0.001501229,-0.015994641,-0.017126544,-0.058114107000000005,-0.052030869,-0.022976708,0.027212418999999998,0.024123672999999998,-0.033175846,0.030173389,-0.065256655,0.033267374,-0.042400874000000005,0.008147787,-0.09699526800000001,-0.019232946,1.4510355940000002,2.370000038,-1.5085273240000001,-1.736321571,-1.4593324280000002,-1.1876507109999999,-2.3278465809999997,-0.831485329,-4.4809437569999995,-0.291165862,-1463.2529030572623 -2316,2316,E145Y,0.039136678,0.021443648,0.039206543999999996,-0.026655111000000002,-0.131728189,-0.09873917900000001,0.005006806,0.073266549,0.106351569,0.030952313,0.011934982,-0.03033284,0.10874592699999999,-0.036317047000000005,-0.016993174,-0.085792674,-0.177663703,1.343824961,2.330025806,-5.598873189,-6.617844657999999,-4.936351341,-5.11924324,-6.29916478,-5.021761925,-6.268809473999999,-1.20131469,-1476.4543832596391 -2317,2317,L146A,-0.034015684,-0.012178268,-0.039606414,0.024280585,-1.532918971,0.07624879,-0.056910185999999995,-0.011121181,0.07147878099999999,-0.020740384,-0.0036161509999999997,-0.036997463,-0.042215365,0.0315296,0.01703157,-1.528424464,-1.5374134769999999,0.6027035070000001,1.314318895,-9.285173624,-9.940624847,-13.44735566,-5.978938667,-8.092017906,-8.966931038,-6.768816994,-2.8885825639999996,-1438.4369390406646 -2318,2318,L146C,-0.09579998699999999,-0.000362203,-0.053614489,-0.434164286,-1.6835959569999999,0.086013509,-0.152356841,-0.039243133,0.091061999,0.041149826,-0.041874232000000004,0.015905065,-0.123134042,-0.068192134,-0.800136437,-1.726291024,-1.64090089,0.717562409,1.310414273,-10.21868455,-11.03765356,-13.80048784,-7.70036515,-9.09180471,-9.463111465,-8.110734371,-5.282824853,-1451.8091526520438 -2319,2319,L146E,-0.016862116,-0.165975894,-1.21986184,-2.3340640269999997,-2.67514971,0.012750069,-0.02464744,-0.009076792,0.086920451,0.044328799,-0.37628058700000006,-1.078448789,-1.3612748909999999,-2.012900152,-2.655227901,-2.565230885,-2.785068535,2.241326417,0.91437846,-12.8766624,-13.52648541,-16.29816574,-10.14197507,-11.78549281,-12.63119297,-10.12035764,-9.384185772999999,-1446.0434623514302 -2320,2320,L146D,0.025355035,-1.397950819,-1.6952170030000002,-2.059260921,-2.8228956239999996,0.019997473,0.029049421000000002,0.021660647999999998,-0.006950625,-1.277565505,-1.518336133,-2.007476018,-1.382957987,-2.529746933,-1.5887749080000002,-2.604956411,-3.040834837,0.344411359,-0.761082742,-13.40042178,-13.91537703,-17.46630545,-10.44640417,-12.12943458,-13.04458768,-10.12035764,-9.384185772999999,-1448.7415461614728 -2321,2321,L146G,-0.058312487,-0.025574837000000003,-0.051067283,-1.5283667419999998,-2.258073028,0.033572789,-0.067787681,-0.048837293,0.08083323099999999,-0.002205999,-0.048943675,-0.063055691,-0.039078874,-1.279300033,-1.7774334509999998,-2.532206298,-1.9839397580000002,0.7942354559999999,0.729943097,-13.39802791,-14.04920962,-17.39055538,-10.1732344,-12.44954675,-12.92759339,-10.05899746,-9.054010444,-1439.609631405212 -2322,2322,L146F,-0.065970032,0.01890785,-0.092772345,-0.040227032999999995,-0.11858342699999999,-0.03242857,-0.148123025,0.016182961000000003,0.018552073999999998,0.036243687000000004,0.001572012,-0.066744833,-0.118799857,-0.104341355,0.02388729,-0.090847525,-0.146319328,1.482664884,2.390179978,-3.538987567,-4.526194229,-5.00133741,-2.008054482,-3.4508934780000002,-2.708458237,-4.053957397,-1.460972022,-1458.0510682933964 -2323,2323,L146I,-0.033802792000000005,-0.028658412999999997,0.016936866000000002,-0.043869964000000004,-0.366678145,0.081841919,-0.029765597999999997,-0.037839986,0.27896421899999996,0.057756836,-0.115073662,0.034503156,-0.0006294240000000001,-0.082274613,-0.005465314000000001,-0.101368149,-0.631988141,1.365435683,2.278024303,-5.414389582999999,-7.610069427000001,-6.047276482000001,-4.49085981,-4.372623062,-4.551119133,-5.016967098,-0.285261651,-1454.9931719624437 -2324,2324,L146H,-0.022100333,-0.029496453,-0.542275262,-1.85043568,-2.870012064,0.09952375699999999,-0.027946117000000003,-0.016254548,0.050633342000000005,-0.016846398999999998,-0.042146507,-0.333822509,-0.750728015,-1.577236408,-2.123634951,-2.673635185,-3.0663889419999997,1.6628242009999998,0.8642970870000001,-11.55926144,-12.21933997,-14.5518184,-9.100822281000001,-10.35627026,-11.56805628,-10.12035764,-9.384185772999999,-1452.8119579469785 -2325,2325,L146K,-0.035675036,-0.938289933,-2.074359593,-2.52644914,-2.628974197,0.112475725,-0.0054643040000000006,-0.065885767,0.138027915,-0.5993507220000001,-1.277229143,-2.077449262,-2.071269924,-2.298690181,-2.754208099,-2.37389966,-2.884048733,0.521770104,-0.492694696,-12.48295839,-13.48456676,-15.429248499999998,-9.839793343,-11.16048743,-12.50069592,-10.12035764,-9.384185772999999,-1451.34530666098 -2326,2326,L146M,-0.13054608,-0.02725167,-0.093790518,-0.159891116,-0.136688725,0.02572644,-0.15458479,-0.106507369,-0.07616268,-0.043048221,-0.011455119,-0.14427626300000002,-0.043304772000000005,-0.107644104,-0.21213812699999998,-0.135317188,-0.138060261,1.487255086,2.265296799,-4.970610904,-6.93948941,-5.136935257,-3.775506607,-4.645992103999999,-4.355131142,-5.646593116,-2.9594584889999997,-1449.743906501215 -2327,2327,L146N,-0.048626605999999996,0.027940094,-1.139823056,-2.318061439,-2.571101493,0.072335759,-0.001589381,-0.09566383,0.260282006,0.041962569000000005,0.013917618999999999,-0.7919527740000001,-1.4876933380000001,-2.243642615,-2.392480263,-2.3188520930000003,-2.823350893,1.706674007,0.634807573,-11.55906459,-13.12404513,-13.79113685,-8.801671089,-10.30998032,-11.76848954,-8.961731592000001,-6.190365436,-1448.2357095149346 -2328,2328,L146Q,-0.040662958,-0.041412686000000004,-0.088883041,-0.782644261,-1.8801027080000001,0.031166042,-0.021382519,-0.059943397,0.044881013,-0.07424534,-0.008580032,-0.176087711,-0.00167837,-0.397328631,-1.167959891,-2.177974156,-1.582231259,1.5909871580000001,1.324879616,-10.36511972,-11.25468963,-12.63250996,-8.33674614,-9.006149391000001,-10.59550349,-8.429290832000001,-6.190365569,-1446.8874779855832 -2329,2329,L146P,-0.056003599,-1.035718776,-1.9764505980000002,-2.218807875,-3.3791381869999997,0.04566176,-0.057969232999999995,-0.054037964,0.09662822900000001,-0.835802699,-1.235634852,-2.061220048,-1.891681147,-2.118268931,-2.319346818,-2.846690924,-3.91158545,0.368269364,-0.581711185,-12.37640949,-13.02205361,-16.56278421,-9.019304909,-11.18262725,-12.09527749,-9.19881765,-6.6563888470000006,-1450.3922480586916 -2330,2330,L146S,-0.06944122,-0.057805539,-1.415366165,-2.025867845,-2.745330081,0.079292052,-0.053679787,-0.085202653,0.098424322,-0.013868868999999999,-0.101742208,-1.257461942,-1.573270388,-1.846679647,-2.205056042,-2.751192899,-2.7394672630000003,2.515883397,1.10419167,-11.89824601,-12.72011503,-15.36214629,-8.827651711,-10.91869865,-11.66261837,-8.657114141000001,-6.0459106060000005,-1438.5250208489597 -2331,2331,L146R,-0.043560151,-1.194805012,-2.174264603,-2.354320129,-3.4083901780000003,0.034947364,-0.058388322,-0.02873198,0.076177064,-1.088294476,-1.301315547,-2.22474517,-2.123784036,-2.078009304,-2.6306309530000003,-2.7552787739999998,-4.061501582,0.185175308,-0.6800990309999999,-12.52922387,-13.03829427,-15.92097142,-9.993565903,-11.13436214,-12.55892561,-10.12035764,-9.384185772999999,-1449.17987171188 -2332,2332,L146T,-0.079174973,-0.006270625,-0.08897277199999999,-1.066424827,-2.590170917,0.061118060999999994,-0.062686115,-0.09566383,-0.008730118,-0.047631847000000005,0.035090597,-0.10346370699999999,-0.074481836,-0.631877504,-1.500972149,-2.349304112,-2.831037722,1.6756821130000001,1.280096763,-10.0039412,-11.30785107,-13.44700188,-7.184416245,-8.678493317000001,-9.401943512,-7.285420492999999,-2.709396702,-1446.6078432472423 -2333,2333,L146W,-0.077790712,-0.014155393,-0.070337283,-0.056477677000000004,-2.146566175,-0.037764442,-0.08587489400000001,-0.069706529,0.065356599,0.030424403,-0.05873518900000001,-0.046919935999999995,-0.09375463,0.01010614,-0.12306149300000001,-1.5683101609999999,-2.724822188,0.606928577,1.312592777,-7.33054118,-8.213073227,-10.80822818,-5.336289886,-6.307485695,-5.987628914,-6.582509977000001,-4.255336582,-1453.8014879291877 -2334,2334,L146V,-0.043334429,-0.017956725,-0.078163187,-0.059673077000000005,-0.156148555,0.002177064,-0.09657579599999999,0.009906938,0.0019528120000000002,-0.041239599999999994,0.0053261509999999995,-0.07049134,-0.085835033,-0.056386773,-0.062959381,-0.157170161,-0.15512694900000001,1.482721905,2.2397079769999997,-4.417830127,-6.2298356020000005,-5.18535743,-2.135071175,-4.063368736,-4.4755176930000005,-3.748030633,0.473506039,-1456.34204255417 -2335,2335,L146Y,-0.106303734,-0.074100141,-0.103564794,-0.074514093,-2.1793686969999997,0.027281917000000003,-0.159495989,-0.053111479,0.14701145699999998,-0.033423573,-0.114776708,-0.098383169,-0.108746419,-0.026711982999999998,-0.12231620300000001,-1.680069295,-2.678668098,0.22949301800000002,1.298430085,-7.680214232999999,-8.520546555,-10.58918765,-5.7606217189999995,-6.965394066,-6.565321175,-6.578878692999999,-4.295425403,-1447.8463300685398 -2336,2336,T147A,0.022062627,0.011389082,-0.010877535,-0.037556241000000004,-1.3871233980000002,0.017455101,0.055586450999999995,-0.011461197,-0.019409335,-0.038278711,0.061056874000000004,-0.069506412,0.047751342999999995,-0.059105944,-0.016006537,-1.399782544,-1.374464251,0.7544140859999999,1.331212557,-7.667339949,-6.604745415,-7.809783325,-8.900242683,-7.590012428,-7.431915893999999,-5.668000225,-2.258778971,-1440.341884703841 -2337,2337,T147C,0.038408812,-0.071621238,-0.03330638,-0.026731487,-0.308931309,0.009069435,0.027030176,0.049787447,-0.059343735999999994,-0.09728274099999999,-0.045959735,-0.077734839,0.011122078999999998,-0.06850722,0.015044247,-0.28005605,-0.337806568,1.617178365,2.167237634,-12.62910189,-11.64320908,-12.7559272,-13.86768423,-12.08303527,-12.79565366,-10.41234147,-7.632187008,-1448.90643997211 -2338,2338,T147E,0.08236563200000001,0.036530605,-0.026065612999999998,-0.02011953,-0.607522664,0.041221138,0.104538594,0.060192669000000004,-0.030326121,0.003195778,0.069865432,-0.096585245,0.04445402,-0.07545373400000001,0.035214674,-0.568999503,-0.646045825,1.693560615,1.946044848,-9.734872635,-7.394343208,-7.679792152,-12.37199245,-11.48108213,-9.747153229,-7.198864222,-1.835617294,-1454.2521616341546 -2339,2339,T147D,0.090647072,-0.002851638,-0.014560061000000001,0.023919816,-0.909715515,0.076219948,0.137959369,0.043334774000000006,-0.048461132000000004,-0.029252546,0.023549271,-0.062427207,0.033307086,-0.0541024,0.10194203199999999,-0.841483357,-0.977947673,0.99741864,1.43980217,-10.12408034,-9.283466576,-8.565405701,-12.17729882,-10.87243678,-9.721793822999999,-5.957548871,-1.9213708919999999,-1451.5480083795264 -2340,2340,T147G,0.02756663,0.011423098999999999,0.00387799,-0.017565203999999997,-0.336406679,0.027825601000000002,0.044602592,0.010530666999999999,0.02597774,-0.020075564,0.042921760999999996,-0.044944569000000004,0.052700548,-0.054218974,0.019088567,-0.34415871600000003,-0.328654642,1.493917872,1.978015035,-8.392482777,-8.065321075,-7.210821907000001,-9.883424942000001,-8.858687683,-7.944158279,-6.126722202000001,-3.5776755639999998,-1445.807859708555 -2341,2341,T147F,0.004985754,-0.059418505999999996,-0.238903318,-1.704516287,-2.976655135,-0.001604902,0.045828717000000005,-0.03585721,-0.014846855,-0.10880212800000001,-0.010034884,-0.23292635399999997,-0.244880282,-1.5587357769999999,-1.8502967959999999,-3.043545443,-2.909764827,1.291544744,0.77133782,-13.0486452,-11.87626946,-13.73661357,-16.29012637,-11.90033024,-11.43988638,-8.951110965,-6.099940475,-1450.6546795410104 -2342,2342,T147I,0.070851232,0.019368273999999998,0.032542448,0.006371238,-1.282457123,0.026742172,0.11355024699999999,0.028152216,-0.04843592,-0.000648761,0.039385308,-0.024102044,0.08918694,-0.041968240999999996,0.054710717,-1.0622079759999998,-1.5027062690000001,0.8348817470000001,1.367458187,-11.37532434,-11.65940349,-11.77472894,-11.738057300000001,-11.47842925,-10.226002699999999,-9.361592344,-5.859069174,-1445.2272137650289 -2343,2343,T147H,-0.022954948,-0.032115741,-0.055724518,-0.076693398,-1.292782142,0.089525634,0.032493844,-0.078403739,-0.032644024,-0.00479925,-0.059432232,-0.052569169000000006,-0.058879867,-0.083738746,-0.06964805,-1.200500238,-1.3850640459999999,0.970922935,1.3738640530000001,-12.00539479,-11.795002,-12.12862101,-12.771757899999999,-11.39212447,-11.93946858,-7.917691062,-3.4287596610000004,-1452.135848723352 -2344,2344,T147K,-0.046906224,-0.033257449,-0.055360768,-0.070045941,-0.501617593,0.078192462,0.019628974,-0.11344142199999999,-8.01e-05,-0.047788552000000005,-0.018726345,-0.121651196,0.010929661,-0.084515437,-0.055576444,-0.493784444,-0.5094507420000001,1.7021810290000001,1.992870018,-11.71117919,-11.44621854,-13.72228281,-12.25580257,-9.982599548,-11.14899247,-7.110757453,-2.9004900680000003,-1451.5341797787696 -2345,2345,T147M,0.034932628,0.038274469,0.02025315,0.015128206000000002,-0.314493285,0.024504612999999998,0.08402587800000001,-0.014160622,-0.044782406,-0.039434512000000005,0.11598345,-0.044453791,0.08496009,-0.047215279000000006,0.077471691,-0.323032402,-0.305954168,1.0213265740000002,1.661118937,-9.26300276,-9.731393074,-9.440511238,-9.684614571000001,-9.230287392000001,-8.228207527,-7.343513146,-3.825057316,-1447.9876418556087 -2346,2346,T147L,-0.017113803,0.014193303999999999,-0.018917853999999998,-0.01216079,-1.710683524,0.030979958,0.024882067,-0.059109673,-0.04991600400000001,0.013444981000000002,0.014941626000000001,-0.043432969,0.0055972619999999996,-0.025622002,0.0013004219999999999,-1.573302796,-1.848064251,0.584183557,1.3113530979999999,-12.88251127,-13.20701052,-14.39724349,-13.18123598,-13.13496415,-10.4921022,-9.720364342,-6.657958814,-1436.5346420169808 -2347,2347,T147N,-0.038856954,-0.08720346400000001,-0.043146294,-0.057624507,-0.119655975,0.051518822,-0.030319695,-0.047394213,0.018634618000000002,-0.072463634,-0.101943293,-0.093209145,0.006916556999999999,-0.08175471599999999,-0.033494297,-0.109720839,-0.12959111,1.554629113,2.398005756,-6.042720021,-6.414056778,-5.1149969639999995,-7.758409164,-5.018322853,-5.907814346,-5.7644382279999995,-0.19384504600000002,-1454.7600597068667 -2348,2348,T147Q,0.049848489,-0.064887079,-0.006934806,-0.026956711,-0.223975582,0.056022228,0.082244629,0.017452349,0.006748488,-0.036449277,-0.09332488,-0.034783121,0.020913509,-0.029826983999999997,-0.024086437999999998,-0.141638347,-0.306312817,1.364063412,2.208153016,-9.635149107,-8.835056831000001,-9.019253609,-10.2383288,-10.51477368,-9.568332611,-5.359546412,-1.408534912,-1460.0601701452397 -2349,2349,T147P,-0.002512085,-0.038981717,-0.012788896999999999,-1.30489685,-2.288112346,0.059525180999999996,0.025272633,-0.030296802999999997,-0.039177797,-0.035082581,-0.042880853,-0.06491985,0.039342056,-0.786656523,-1.823137176,-2.1311938980000003,-2.445030793,1.920090641,1.380818631,-13.16452117,-12.26979005,-13.956599300000002,-13.67329617,-13.13581473,-12.78710557,-9.292108657,-5.448707295,-1462.1429854012094 -2350,2350,T147S,0.021301805,-0.005765296,0.010263309,-0.032975752000000004,-0.098120435,-0.002349005,0.036401396,0.006202213000000001,0.003624683,-0.036191008,0.024660416,-0.030810097999999998,0.051336716,-0.0467495,-0.019202003,-0.10393918199999999,-0.092301687,1.4178042830000002,2.340412478,-7.468601903,-7.192710915,-6.892370529,-8.909827095,-7.185879974,-7.162221001,-6.672827462000001,-3.9442720639999997,-1447.0048494767398 -2351,2351,T147R,0.037036407,0.019985377,0.019748768,-0.0036298090000000003,-0.122255423,0.145202149,0.087494768,-0.013421954,-0.09962322400000001,0.018774986,0.021195767,-0.047824899000000004,0.087322435,-0.050615138,0.04335552,-0.161346192,-0.083164653,1.629188205,2.365289872,-10.84258707,-10.94889198,-11.72583983,-9.769808487,-9.800727448,-11.96766761,-6.577469245,-2.207437122,-1447.2547345608473 -2352,2352,T147W,0.014383551999999999,-0.0013591760000000001,-0.008024587,-0.893420022,-2.021586879,0.030176718999999998,0.042105385,-0.013338281,-0.030263125,-0.058050397999999996,0.055332047,-0.07150786599999999,0.055458692999999996,-0.514089079,-1.272750965,-1.87461456,-2.168559198,1.787464926,1.449327755,-13.96691795,-13.02773247,-14.85883616,-15.0155601,-13.23193417,-13.70052685,-9.283797723,-6.099940577999999,-1459.2720746323466 -2353,2353,T147V,0.072394674,0.058004098,-0.001758824,-0.029396437999999997,-0.09750000199999999,-0.0005054980000000001,0.091685169,0.053104179,-0.05681135599999999,-0.021290375,0.13729857,-0.096363315,0.092845668,-0.059741442,0.0009485660000000001,-0.154209305,-0.040790698,1.4252966230000002,2.215574258,-10.1901212,-10.381015199999998,-10.45105201,-9.946382339,-10.22518117,-9.946975304,-8.756306696000001,-5.263357834,-1446.566735346336 -2354,2354,T147Y,-0.019430118,-0.034379109,0.009364239,-1.5980526519999998,-2.680316153,0.062267874,0.026428242999999997,-0.06528847900000001,-0.031025482000000004,-0.040684114,-0.028074104,-0.049917475999999995,0.068645953,-1.4228583559999999,-1.7732469469999999,-2.583775144,-2.776857161,0.622004561,0.7097921140000001,-14.90103684,-13.80006189,-15.17759801,-17.60993013,-13.42868655,-14.48890765,-10.12983299,-7.15000833,-1452.0362890339456 -2355,2355,A148C,0.0016441960000000001,-0.002224891,-0.05808538,0.005528764,-0.15431756300000002,0.017589066,0.0065150569999999994,-0.003226665,0.016128025,0.010538252,-0.014988033999999999,-0.09213560900000001,-0.02403515,-0.036644692,0.047702219000000004,-0.091848011,-0.21678711399999998,1.462228225,2.3775213859999997,-6.681457357999999,-6.161983977999999,-6.971356865,-7.38091674,-5.801538077999999,-7.091491127,-7.888532184,-6.325314992999999,-1460.7910439185798 -2356,2356,A148E,0.0288149,0.029431551,-0.0790964,-0.0012719769999999999,0.024932066,0.00027529,-0.010665198999999998,0.06829499900000001,0.084247633,-0.006363376,0.065226477,-0.084475779,-0.073717021,-0.049774439000000004,0.047230485,-0.057088846,0.10695297699999999,1.4150974180000002,2.441672406,-1.659040453,-1.763940895,-1.3824569169999998,-2.190363571,-0.602351685,-2.356089195,-3.766807434,-1.085094486,-1457.1321409139782 -2357,2357,A148D,-0.03426742,-0.0007987010000000001,-0.014351461999999999,-0.008885485,-0.013729766000000001,-0.011685063999999998,-0.067733818,-0.0008010210000000001,0.09204178199999999,0.018704847,-0.020302248999999998,-0.010116199000000001,-0.018586724,-0.007687123000000001,-0.010083846,-0.024493481,-0.00296605,1.237023233,2.517427644,-1.774264165,-1.990384323,-1.663711395,-1.800460587,-1.169771034,-2.246993485,-4.012036294,-1.4869570090000002,-1457.9307594867423 -2358,2358,A148G,0.033317532000000004,0.015772027,-0.018914038,-0.012160497,-0.016463353,0.000937439,0.02479992,0.041835144,0.052060125,-0.012909008999999999,0.044453062,-0.082076356,0.044248280999999993,-0.021801378,-0.002519616,-0.063288497,0.030361792000000002,1.339784948,2.420667763,-2.8712081119999997,-2.6944537810000004,-2.8946206969999997,-2.913121948,-2.687377182,-3.1664669489999997,-4.146690507,-2.349109237,-1461.1386982472613 -2359,2359,A148F,0.09529546300000001,-0.049373701,0.0037776290000000002,0.002475958,-0.031785314,0.069537373,0.056005760999999994,0.134585165,0.045076019,-0.08527966,-0.013467742,-0.101047341,0.10860259900000001,-0.047828324000000005,0.05278023900000001,-0.061469181,-0.002101447,1.333538799,2.44493706,-6.91025022,-5.62188427,-7.185521698,-8.247621376,-5.747433022,-7.748790733,-7.570707088,-5.757002846000001,-1463.9047204959206 -2360,2360,A148I,0.061226822,0.035919322000000004,-0.037801537999999996,0.095323611,0.019962406000000002,0.182397643,0.054101554,0.068352089,-0.073272386,0.072767756,-0.000929112,-0.078855077,0.003252002,0.021437295,0.169209926,0.055313439000000006,-0.015388628,1.259491033,2.8930176839999997,-6.083708322000001,-5.5475877229999995,-6.207755402,-6.327977897999999,-4.855540756,-7.479679832,-7.029212641,-5.311291291,-1459.8038646443747 -2361,2361,A148H,0.047705551,0.018955911000000002,-0.020074345,0.03410161,-0.0026922020000000003,0.012621841000000002,0.03143757,0.063973532,0.053151119000000004,-0.015341282,0.053253104,-0.041827197,0.0016785079999999998,-0.030146851000000002,0.098350071,-0.036758658,0.031374255,1.2707848640000001,2.459244756,-3.7366857889999996,-3.0361629260000003,-4.153887299,-4.081775177,-2.980743317,-4.430860228999999,-4.534694789,-3.2314832260000004,-1459.5171924280003 -2362,2362,A148K,0.005032661,0.047761797,0.016127241,-0.038354341,0.03095493,0.058522425,0.003800514,0.006264808,0.048260101,0.030428302999999997,0.065095291,-0.004903119,0.037157601,-0.04934697,-0.027361711,0.052547474000000004,0.009362386,1.12299802,2.676988626,-2.238199545,-2.071065842,-2.57423922,-3.281260521,-0.622791718,-2.641640427,-3.6090427910000002,-1.286113865,-1458.4652121313848 -2363,2363,A148M,0.136325088,-0.047523380999999996,-0.005670045,-0.084710624,0.033247698,-0.12731969,0.106028778,0.166621397,-0.23297322899999998,-0.090576,-0.0044707620000000005,-0.20212418899999998,0.19078409899999998,-0.052708872000000004,-0.11671237599999999,-0.09128435800000001,0.157779753,1.360739959,2.268562279,-5.380625565,-5.116868408,-5.454628639,-6.054601097000001,-4.368098282,-5.908931396,-6.541269375,-4.498290021,-1460.2384178321809 -2364,2364,A148L,0.027296894,0.029859424,0.010759302,0.050459807,0.047229992,0.024906584,-0.00182183,0.056415617,0.068215124,0.054789045999999994,0.004929801,-0.012046606999999999,0.03356521,0.027391367000000003,0.07352824599999999,0.027262911,0.067197073,1.339338372,2.847961086,-4.790198767,-4.205386505,-5.262026917,-5.245268135,-3.469557289,-5.76875499,-5.2175746610000004,-3.3823775510000003,-1461.7585854777135 -2365,2365,A148N,0.008472485,-0.0092706,-0.015659933,0.071364457,-0.021430817,0.025021053999999997,-0.000344803,0.017289772,0.042522971,0.021274362999999998,-0.039815563,-0.015813765,-0.015506101000000001,0.085178034,0.05755088,-0.000203889,-0.042657744000000004,1.3201650059999999,2.677285894,-2.989942674,-2.680794739,-3.110477608,-3.7479957280000002,-2.103064224,-3.307381073,-4.831246384,-2.185656255,-1454.456924249418 -2366,2366,A148Q,-0.011222939,0.026698921,-0.032164215,0.026740219,-0.032812593,0.0052951840000000005,-0.035682211,0.013236333999999999,-0.012347107,0.018140804,0.035257038,-0.051949875,-0.012378555,-0.008998987,0.062479425,-0.066096798,0.000471613,1.324961646,2.4028156430000003,-1.976998178,-1.467542244,-2.018750351,-2.7859823460000004,-0.94172773,-2.67098822,-3.846641902,-1.067410795,-1461.0225618556142 -2367,2367,A148P,0.015720608,0.021313852999999997,-0.026915419,0.006047456999999999,-1.3817948759999998,0.054266300999999996,0.019659568,0.011781647,0.03050882,0.002240727,0.040386978999999996,-0.057372285999999995,0.003541448,-0.013512756,0.02560767,-1.416467434,-1.347122318,0.6040975439999999,1.319491312,-5.487982811,-4.680855011,-5.014827553,-6.391617073,-4.928239288,-6.42437513,-6.8910845489999994,-4.482013792,-1450.5503791146912 -2368,2368,A148S,0.024507357,-0.028076865,-0.014147682,0.01260874,-0.047102173,-0.016079443,0.001503791,0.047510922000000004,0.041785972000000005,-0.003936943,-0.052216785999999994,-0.049767285,0.021471921,-0.016028352,0.041245831000000004,-0.051366209,-0.042838136,1.272351541,2.38649509,-1.860157939,-1.620459145,-1.91235936,-2.681492973,-1.1387024,-1.9477758180000002,-2.678527456,-1.8424915530000001,-1456.8575589805841 -2369,2369,A148R,0.056977379,0.012031408,0.00509983,0.0177334,0.019409463000000002,0.0050142979999999995,0.04299103,0.070963728,-0.026528983,-0.005931158000000001,0.029993972999999997,-0.06449213,0.07469179,-0.025674942000000003,0.061141741,-0.038595071,0.077413997,1.331553658,2.489237444,-1.5384619169999998,-1.090633202,-2.005216446,-1.496868355,-1.117170029,-1.982421555,-3.025063717,-0.7768873359999999,-1458.2009640526958 -2370,2370,A148T,0.032737141000000004,-0.020103024,-0.020914089,-0.004093654,-0.040016796,0.014325465,0.027633235,0.037841046,0.053397299,-0.006777759,-0.033428288,-0.071073467,0.02924529,-0.021286575,0.013099268,-0.020720102,-0.059313489000000004,1.278865205,2.3815814459999998,-2.09942028,-1.9365991359999999,-2.13792115,-2.356985512,-1.241464745,-2.824130859,-3.291314823,-2.200589491,-1452.3083425248042 -2371,2371,A148W,0.10885759,0.076481021,0.028562625,0.030399474,-0.039664242,0.016883383999999998,0.12680037,0.090914809,0.050402028,0.016604056000000002,0.136357985,-0.018903023999999997,0.076028274,-0.007527521999999999,0.068326469,-0.1208961,0.041567616,1.374599104,2.294895244,-6.504989421,-5.489832855,-6.790646561,-7.228506317000001,-5.799230782,-7.216730591,-7.403794182,-5.431339991000001,-1466.2062695850618 -2372,2372,A148V,0.05349313,-0.008821716,-0.044994692999999995,-0.011312445,0.0030992859999999997,0.058461331,0.04827026,0.058716,0.007038365,-0.05089029,0.033246859,-0.096467144,0.0064777590000000005,-0.047258802999999995,0.024633914,-0.072213103,0.078411674,1.37892799,2.3714800169999997,-4.364630952,-3.877420654,-4.545561493,-4.858937019,-3.408264175,-5.13297142,-5.300264652,-3.87726509,-1461.3354270821437 -2373,2373,A148Y,-0.017991726,-0.080737102,-0.09841883300000001,-0.00284377,-0.126288959,0.056337440999999995,-0.042099011,0.00611556,0.139031045,-0.029850715,-0.131623489,-0.063297139,-0.133540527,0.018695358999999998,-0.024382899,-0.08897595,-0.16360196800000001,1.336557061,2.30175345,-7.081957329,-5.790491272000001,-7.40847879,-8.332373131,-5.808967094,-8.069476357000001,-7.693808579,-5.85464797,-1461.2720028278418 -2374,2374,F149A,0.040286465,0.060909383,-0.016501785,-0.033655895,-0.582402575,0.004158413,0.027562535,0.053010394,0.002018804,-0.012020147,0.133838913,0.006837811,-0.03984138,0.01999157,-0.08730336,-0.43038805399999996,-0.7344170959999999,0.783446995,1.492646231,-10.32655865,-8.020104247999999,-12.62823712,-13.61807543,-8.830995232000001,-8.535381218,-4.733122938,-1.519623259,-1452.523382339161 -2375,2375,F149C,0.059576734000000006,0.09486982699999999,0.011257841999999999,0.022014554,-1.6169616740000001,0.094867855,0.06525333,0.053900137,0.017271263999999998,-0.026734301000000002,0.216473954,0.036872501,-0.014356817,0.027727401000000002,0.016301706000000003,-1.535603302,-1.698320045,0.649342845,1.31668358,-10.96814646,-9.097073029,-12.38646564,-11.76214357,-11.37881529,-10.21623479,-7.124339075,-3.3659497710000004,-1457.5086591672152 -2376,2376,F149E,0.002007039,0.100715267,0.011505175,-0.020404046000000002,-1.318017717,-0.022971041,0.06354565599999999,-0.059531577999999995,0.022476537,-0.038484626,0.239915159,0.031961601,-0.008951251,-0.003285342,-0.037522749,-1.164231735,-1.4718036980000002,0.740227027,1.3485844009999999,-12.04548338,-9.609107071,-13.79513521,-14.16214963,-9.853826377999999,-12.80719863,-6.556943344,-2.382055233,-1455.8032795991749 -2377,2377,F149D,0.007066676,0.044556634000000005,-0.002155516,-0.006561474,-1.7228140019999998,0.048427541,0.069722747,-0.055589396,0.044351910999999994,-0.0014249579999999998,0.090538225,0.014626422,-0.018937453,0.05407933,-0.067202278,-1.55433228,-1.891295723,0.8001617659999999,1.3251937329999999,-13.45469605,-10.57104749,-15.11081541,-16.21398959,-12.19730969,-13.18031808,-6.550279201,-3.52725783,-1459.4923973842524 -2378,2378,F149G,0.053034822999999995,0.099121435,0.03770568,-0.547502585,-1.767180068,0.055481447999999996,0.069452643,0.036617002,-0.026048857,-0.020379766,0.218622635,0.032775096000000004,0.04263626400000001,-0.174326874,-0.920678296,-1.83891709,-1.6954430459999998,1.104288071,1.326902868,-13.12006158,-11.31522638,-13.94873898,-15.644071499999999,-11.75544701,-12.93682403,-6.647444075,-3.8199867860000003,-1452.9220721838064 -2379,2379,F149I,-0.000160379,0.08338429900000001,0.024293341,0.020608355,-0.067300137,0.021107062000000003,0.020140911,-0.020461668,-0.044551123,-0.004759439,0.17152803600000002,0.051608954000000005,-0.0030222720000000003,0.071175591,-0.029958882000000003,-0.040222255,-0.09437801800000001,1.29224426,2.637785846,-9.864096999,-7.527008522,-11.36589468,-11.49187062,-8.799048767,-10.1366624,-5.636649128999999,-2.821442962,-1455.1165436240844 -2380,2380,F149H,0.039914892,0.063269795,0.026776955,-0.005875142,-0.5655513120000001,0.060617624,0.047965500999999994,0.031864283,0.0333586,-0.022989452999999997,0.149529043,0.0338525,0.019701409,-0.017772798,0.0060225140000000005,-0.48056964700000004,-0.650532977,1.316234439,1.7582979380000001,-10.05514,-9.670787354,-11.05214809,-10.71742863,-9.917519172999999,-8.91781678,-6.397315547000001,-3.7877049439999997,-1458.888277144637 -2381,2381,F149K,-0.032924389,0.056922600999999996,-0.039732013,-0.027358441,-1.31821425,0.006102804,0.09144520699999999,-0.157293985,0.034573498,-0.07316903400000001,0.18701423600000003,-0.044619877,-0.034844148,0.00149909,-0.056215970999999997,-1.3600670519999998,-1.276361447,0.768398305,1.335675711,-12.82191288,-10.05416396,-14.53259662,-15.00312672,-12.18763982,-12.33203728,-6.085602987000001,-3.3557139210000004,-1457.591197034344 -2382,2382,F149M,0.098619145,0.09203110800000001,0.09320669,0.054909558,-0.010095765,-0.017257939,0.121460043,0.075778246,0.017887995,-0.048266539000000004,0.232328755,0.06885951900000001,0.11755386,0.06502738799999999,0.044791727,-0.042547497999999996,0.022355969,1.2452987340000001,2.5215486940000003,-8.597977412,-7.402101852,-10.51820609,-7.70014254,-9.020210724,-8.349225853,-6.05753849,-2.609377384,-1457.4100161930546 -2383,2383,F149L,0.031110656,0.08866229199999999,0.038625162000000005,0.005882525,-0.262966181,0.0029214809999999996,0.06753949299999999,-0.005318181999999999,0.007627269,0.012389997,0.164934587,0.090663226,-0.013412903,0.037997477,-0.026232427000000003,-0.20178135100000003,-0.32415101,1.4954448040000001,2.219955252,-6.984806213,-5.887959732000001,-8.16932563,-6.538271187,-6.598287506,-7.730187012000001,-4.301733502,-1.364094085,-1451.219487958122 -2384,2384,F149N,-0.035530906,0.096952001,0.046421682,-0.03676396,-1.70591085,0.035952536,0.015378863000000001,-0.08644067400000001,0.0016239660000000001,0.007943888,0.18596011399999998,0.055679455,0.037163907999999996,0.069249593,-0.142777512,-1.571662167,-1.840159532,0.49966365799999996,1.30860262,-13.40351785,-10.85361479,-15.65903705,-14.94843861,-13.17108476,-12.38541405,-7.3324377489999994,-4.634775901,-1460.2479801336303 -2385,2385,F149Q,0.035587671,0.134240325,0.00973854,-0.019069881,-1.0905521870000001,0.011499466000000002,0.07252898099999999,-0.00135364,-0.021115167999999997,4.26e-05,0.268438049,0.030281542,-0.010804463,0.004505474000000001,-0.042645235999999996,-0.644967547,-1.536136826,0.717539268,1.408916111,-12.86427143,-9.642229324,-14.19237731,-15.31577441,-11.83568346,-13.33529263,-5.995322775,-3.1922848339999996,-1458.053951030597 -2386,2386,F149P,-0.000369375,-0.851965643,-1.979390965,-2.3406094630000003,-3.1968574810000003,0.057785030999999994,-0.0033126109999999996,0.002573862,0.086561395,-0.615921449,-1.088009836,-1.8986676219999998,-2.060114307,-2.084839961,-2.596378965,-2.7446129389999996,-3.6491020219999997,2.8535484639999997,0.9404147890000001,-15.89338192,-13.48252468,-18.03496117,-17.64867516,-15.51378389,-14.78696469,-10.21044336,-9.087452226,-1464.882500137668 -2387,2387,F149S,0.027881156,0.074545352,0.015578222,-0.002463083,-1.357072082,0.02949975,0.022319651,0.033442661,-0.028270099,-0.016346511,0.165437215,0.053527276,-0.022370832,0.043077329000000004,-0.048003494,-1.185682257,-1.5284619069999998,0.770383588,1.3473931469999998,-11.10537738,-8.752261269,-13.46157404,-12.66738418,-11.02219539,-9.623472031,-6.048349197,-2.637172638,-1459.7640874302015 -2388,2388,F149R,0.059749899,0.128760614,0.07071086900000001,0.021153243,-1.3596861269999998,0.040158888999999996,0.07277262400000001,0.046727174,-0.010827301999999999,-0.008139344,0.265660571,0.071548657,0.06987308099999999,0.053551967,-0.011245481000000002,-1.28173653,-1.4376357240000002,0.561401425,1.323358187,-12.06967206,-8.664966179,-12.68169221,-15.31616233,-12.47617533,-11.20936423,-6.333587406,-1.402821157,-1455.6204139273614 -2389,2389,F149T,0.0018859760000000001,0.079642171,0.025121984,-0.016112233,-0.633217506,0.013003385,-0.004325725,0.008097677,-0.04428184,0.004936383,0.154347959,0.08625588199999999,-0.036011915,0.028957785,-0.06118225,-0.46292296299999997,-0.8035120490000001,0.773657927,1.476857317,-11.29191496,-8.188310486,-14.13101454,-14.11273743,-11.52987959,-8.497632759,-5.6749769070000005,-1.259765276,-1463.9341975422576 -2390,2390,F149W,0.06461485,0.10923530199999999,0.034816718999999996,0.018352703999999997,0.10653064699999999,-0.027555102,0.054669802999999996,0.074559897,0.040985026,-0.045089955,0.263560558,0.02369736,0.045936078,-0.00828885,0.044994257,-0.000490258,0.213551552,1.1989643,2.538207767,-5.671315671,-5.280903953999999,-5.410339088,-4.612119034,-5.85590226,-7.197314017999999,-4.5969943010000005,-1.5418668969999998,-1459.0374563708901 -2391,2391,F149V,-0.019289679,0.07274538,0.026812948,-0.045842744000000005,-0.43459985799999995,0.006302969,0.015632935,-0.054212292999999995,-0.04718747,-0.030341485,0.175832244,0.082483339,-0.028857444,0.02851307,-0.120198557,-0.317187056,-0.55201266,0.9360036140000001,1.647982485,-9.942329851,-7.447230835,-12.22129475,-11.89783201,-8.510326088,-9.634965576,-6.237694734,-1.9306202540000001,-1457.538229665719 -2392,2392,F149Y,0.044560399,0.06797758599999999,0.03486357,0.002598509,0.016628017,-0.070360452,0.07456057599999999,0.014560222,-0.022265617999999997,-0.016635298,0.15259047,0.017400775,0.052326365,-0.017019532,0.02221655,0.018287433999999998,0.0149686,1.120864082,2.612443991,-2.7349216710000004,-2.394275696,-2.887829697,-2.43709314,-3.458864502,-2.496545319,-2.132023946,-0.7033977779999999,-1464.3027745545842 -2393,2393,L150A,-0.023584839,0.001733995,0.027900282999999998,0.02703957,-0.21227069399999998,0.052746188,-0.031796765,-0.015372911999999999,0.03156621,-0.018118727,0.021586716000000002,0.039731819,0.016068746999999998,0.046827815999999994,0.0072513230000000005,-0.167394494,-0.257146893,1.2036966340000002,2.047301484,-8.144220461,-8.71687999,-8.895113777,-7.504944878,-5.44997477,-10.15418889,-4.693826241,-0.821271685,-1452.887104797177 -2394,2394,L150C,-0.002671534,0.00739807,0.021204176,0.020484061,-0.476126661,0.013315117,0.013900976,-0.019244043,0.032001343,0.01337604,0.0014200999999999999,0.058969542,-0.016561191,0.06760157900000001,-0.026633457000000003,-0.35071296700000004,-0.601540355,0.564801113,1.4576833619999998,-11.18288795,-12.37227635,-12.47233546,-10.29001392,-10.07531344,-10.70450057,-5.6860909479999995,-2.208912991,-1458.2684415406547 -2395,2395,L150E,-0.08837166699999999,-0.093591989,-1.219768392,-2.190217996,-2.8788484210000003,0.090897126,-0.077625975,-0.099117359,0.106920165,0.059886385,-0.247070362,-0.784071574,-1.65546521,-1.6570080969999998,-2.723427894,-2.8440027189999997,-2.913694122,2.139324044,1.036520662,-14.81219449,-14.91566449,-15.96125401,-14.81466446,-13.16431033,-15.20507917,-9.030679088,-7.110701665,-1463.8022455936298 -2396,2396,L150D,-0.148466565,-0.409866169,-1.311951202,-1.787175184,-2.440127655,0.0647391,-0.154956903,-0.14197622699999998,0.025955715,-0.13442969400000002,-0.685302643,-1.428510164,-1.195392239,-1.749553305,-1.824797063,-2.497215233,-2.383040076,3.285344165,1.737945696,-16.20151136,-15.98421342,-17.80841623,-15.97809306,-14.20976674,-17.02706735,-9.964609497,-9.414628367,-1464.5292466497049 -2397,2397,L150G,-0.037781783,0.053545522000000005,0.026022831,-0.238188437,-1.7566855730000002,0.07305187,-0.023828772999999998,-0.051734793,0.054184264,-0.008015019,0.11510606300000001,0.004452308,0.047593353,-0.017776003000000002,-0.458600871,-1.849582597,-1.663788548,0.866081733,1.311837357,-13.51054475,-13.66037441,-14.50035725,-13.242819500000001,-11.10401696,-15.04515563,-7.128239392999999,-4.23882271,-1458.0765522271395 -2398,2398,L150F,-0.06644371,0.063259295,0.0030953609999999996,0.031013823,-0.14995674,0.09609187400000001,-0.005511754000000001,-0.127375666,0.04734172,0.088658128,0.037860461,0.029646777000000003,-0.023456056,0.167080067,-0.10505242099999999,-0.06585146900000001,-0.23406201,1.543610422,3.106887046,-4.9230298569999995,-3.9379356839999997,-7.327540894,-4.555425735,-4.754539436,-4.039707535,-4.322044208,-1.474033409,-1447.6982476636767 -2399,2399,L150I,-0.035805746,0.005854104000000001,0.026517584,0.012605325,-0.107601528,-0.063500446,-0.052608076,-0.019003415,0.242143943,-0.006801819000000001,0.018510026000000002,0.067094497,-0.01405933,0.0276528,-0.00244215,-0.06964445799999999,-0.145558598,1.377796773,2.5008891269999998,-5.7350223279999994,-4.868571037,-7.175873985,-6.208252174,-4.025719948,-6.396694496,-4.466925568,-0.9854577309999999,-1464.1893428517506 -2400,2400,L150H,0.010326974000000001,-9.84e-05,0.013194441999999999,-0.68746154,-2.50799963,0.051910324,0.032624475,-0.011970528000000001,0.148082516,-0.006530045,0.006333318,-0.026236669,0.052625553,-0.279213223,-1.0957098570000001,-1.947073041,-3.0689262189999997,1.346444244,1.341517906,-14.98430627,-16.49960552,-16.56049813,-13.94391112,-13.26248879,-14.65502776,-9.170114389,-7.110701665,-1458.5109629435465 -2401,2401,L150K,-0.18199730100000003,-0.8417344040000001,-1.9733879840000002,-2.446042147,-2.676445598,0.047433311,-0.191696332,-0.17229827,0.068956485,-0.427227976,-1.256240832,-2.13148291,-1.8152930580000002,-2.054586043,-2.8374982510000004,-2.501217975,-2.8516732210000004,0.750088025,-0.35224161,-14.66709831,-14.92348183,-16.29221439,-14.73180854,-12.662577800000001,-14.725408999999999,-9.232420879,-7.110701665,-1464.1410765484907 -2402,2402,L150M,0.09258706900000001,0.179335212,0.112077513,0.091372157,0.09140153300000001,-0.049605820999999994,0.084471135,0.10070300199999999,0.22953557800000002,0.091185106,0.267485317,0.056329446,0.16782557899999997,0.080349082,0.10239523199999999,-0.014499317,0.197302383,1.100080585,2.476287868,-3.1165467189999996,-3.1796852110000002,-2.8438329469999997,-4.543422722,-2.636067726,-2.379724991,-2.88821799,-0.9404472490000001,-1453.179271076806 -2403,2403,L150N,-0.017720253000000002,-0.014225482,-0.014509528,-0.030351361,-2.256755267,0.060836282,0.015712016000000002,-0.051152522,0.21805576100000001,-0.011782754,-0.016668209,-0.030387333,0.001368278,0.072838474,-0.133541195,-1.867483815,-2.6460267180000003,0.496138171,1.2979856779999999,-14.18204029,-15.00603425,-14.426244199999998,-13.98019204,-12.33575796,-15.16197301,-8.138807374,-5.674645896,-1461.8629950014874 -2404,2404,L150Q,-0.07553734,-0.062725079,0.013701327,-0.227173863,-1.5523361119999999,-0.003981943,-0.063550274,-0.087524406,-0.0037563229999999998,-0.059548428,-0.065901729,-0.031409603,0.058812257,-0.031108887999999998,-0.42323883799999995,-1.473891804,-1.6307804190000001,0.817772387,1.328862368,-14.08945655,-14.81496547,-14.91342899,-14.50094481,-12.18209534,-14.03584814,-9.229588847999999,-7.110701665,-1462.6525626317598 -2405,2405,L150P,-0.065382715,-0.5918797579999999,-1.832835433,-2.193421863,-3.1528743219999997,0.13295653400000002,-0.05167147,-0.079093959,0.066893855,-0.363832692,-0.819926824,-1.7772216019999998,-1.888449263,-1.9606097619999998,-2.426233963,-2.7861584660000003,-3.519590178,2.961349662,1.195106381,-13.95135334,-14.78890691,-16.01038294,-14.10014202,-10.77193285,-14.08540197,-8.052557913,-5.4530760439999995,-1465.386641482357 -2406,2406,L150S,-0.046776632,0.0065802840000000005,0.016289713,0.023886551000000002,-1.7332327109999999,0.07554303700000001,-0.037579605,-0.055973659,0.044787858,0.006563462,0.006597106,0.008949516999999999,0.023629908999999998,0.050579541,-0.00280644,-1.554219363,-1.912246059,0.528071421,1.3099474009999998,-12.07809325,-12.83869256,-12.12662861,-11.19378027,-9.692075134,-14.5392897,-6.961312436,-4.0693790530000005,-1455.2960893618874 -2407,2407,L150R,-0.053265797999999996,-1.0217393540000002,-2.230770936,-2.4613900419999997,-3.2023881419999998,0.11422646199999999,-0.020167505,-0.08636409,0.098114714,-0.85882605,-1.184652657,-2.459076155,-2.002465716,-1.96304998,-2.959730103,-2.652719961,-3.752056322,0.242857089,-0.605414424,-14.66356464,-15.05870915,-15.77528696,-14.96910018,-12.94443404,-14.57029287,-9.0262718,-7.110701665,-1458.3684023562819 -2408,2408,L150T,-0.049834562,0.010273896,0.037321355,0.018731573999999997,-0.568561937,0.058967847000000004,-0.049840529,-0.049828594000000004,0.08289463,0.021523827000000002,-0.000976036,0.06132052599999999,0.013322183000000001,0.048060425,-0.010597276999999999,-0.432077064,-0.705046809,1.1120257709999999,1.65511589,-10.16093898,-10.46579289,-11.99792701,-10.07658891,-7.478969467000001,-10.78541664,-5.826601027000001,-3.147321718,-1456.7554803430103 -2409,2409,L150W,-0.058640560999999994,0.018804504,-0.02076738,0.00017371299999999998,-1.6126777890000001,0.061150674,-0.044170485999999995,-0.07311063599999999,0.126847726,-0.032218605,0.069827613,-0.011952403,-0.029582357000000004,0.02182707,-0.021479644,-1.58580745,-1.6395481280000002,0.540930195,1.309569983,-10.37916801,-12.61706778,-12.43342667,-8.607806931,-9.65004908,-8.587489601,-5.766095277000001,-2.7821227019999997,-1455.5744301932864 -2410,2410,L150V,-0.086111033,0.004775975,-0.0040660340000000005,-0.013784925,-0.09274890599999999,-0.013150112,-0.07524776400000001,-0.096974301,0.103177621,-0.010398032,0.019949981999999998,0.046300800999999996,-0.054432869,0.06487095400000001,-0.092440803,-0.073030053,-0.112467759,1.242938643,2.373763752,-5.985536081,-5.131223442,-6.809540763999999,-6.163364365,-3.9884402239999996,-7.83511161,-4.268977272,-1.717242375,-1452.3147763134912 -2411,2411,L150Y,0.026452536000000002,0.001174105,0.024649657000000002,0.035319501,-0.6687882789999999,-0.091565285,-0.022369983,0.075275055,0.12679602199999998,-0.04677414,0.04912235,0.029006319,0.020292993999999998,-0.000630487,0.07126948799999999,-0.62515948,-0.712417077,1.12631369,1.5505431180000002,-10.84543168,-11.993997,-13.3719113,-10.16871259,-9.384828171,-9.307709335,-6.616223794,-3.8876688589999997,-1448.5623639505357 -2412,2412,H151A,-0.046477107999999996,0.021157649,-0.020395872,0.015322638000000001,0.03070164,0.031942726,-0.0029893529999999997,-0.089964863,0.0066047319999999994,-0.016497253,0.058812551,-0.062303240999999995,0.021511497,-0.050637469000000004,0.081282745,-0.019153563000000002,0.080556843,1.15077845,2.403569891,-1.5858388669999999,-1.835880821,-1.11686821,-0.8176582029999999,-2.43031926,-1.728467842,-3.4964755380000003,0.8444479220000001,-1448.2446862068027 -2413,2413,H151C,-0.045538208,0.025167295,-0.054516722999999996,-0.036545309,-0.143451535,0.042520052,-0.009179281,-0.08189713400000001,-0.011888188999999999,0.014139093,0.036195497,-0.071872483,-0.037160962,-0.062247834,-0.010842784,-0.132103218,-0.154799851,1.605452852,2.414478064,-4.563567526,-4.527917663999999,-4.41438118,-4.26418409,-4.752473061,-4.858881638,-5.1744613,-3.352667046,-1458.6760709797964 -2414,2414,H151E,-0.047776822000000004,0.006297255,-0.033884789,0.033886409,0.044633236,0.06700167,-0.03021653,-0.065337113,-0.045654487,-0.041028821,0.053623330999999996,-0.082410489,0.014640911000000001,-0.023319222999999997,0.091092041,0.018220682,0.07104579,1.173169195,2.582666349,-2.24050645,-2.255801834,-1.6977781140000001,-3.013594978,-2.762445465,-1.472911858,-3.212838432,0.345157791,-1448.4818268464878 -2415,2415,H151D,-0.044039707000000004,0.022865284,-0.06582424099999999,0.008280046999999999,-0.029224302,0.06492058,0.016005791999999998,-0.104085206,0.068952473,-0.018023578999999998,0.063754146,-0.078268978,-0.053379504,-0.0057818769999999995,0.02234197,-0.075783487,0.017334883,1.3347141059999998,2.375770155,-3.470302002,-3.41700042,-2.496059975,-4.205064293,-4.34515802,-2.8882273030000003,-3.396490071,0.04903571599999999,-1459.4580516777933 -2416,2416,H151G,-0.080441065,0.028835296,-0.039573646000000004,0.017249979,0.029651278,0.044385369,-0.0067079340000000005,-0.154174195,-0.004901134000000001,0.015216511,0.04245408,-0.055479394,-0.023667898,-0.018065403,0.052565361,0.0013677,0.05793485599999999,1.230666477,2.641543675,-2.948444298,-3.0671355819999997,-2.8744929889999997,-3.137199028,-3.6472197339999997,-2.016174156,-3.6252899789999997,-1.20003284,-1455.9643835444003 -2417,2417,H151F,-0.045549962,0.017724714,-0.086559009,-0.031241672,-0.018411069,0.052757940999999996,0.006628898,-0.097728821,0.011482734,-0.046858364000000007,0.08230779099999999,-0.145880984,-0.027237032999999997,-0.09420885300000001,0.031725509,-0.098890761,0.062068624,1.399454659,2.2843237530000002,-5.699448418999999,-5.044653404,-5.797788589,-6.27377948,-4.563595345,-6.817425277999999,-5.9878638010000005,-4.276592733,-1461.7999335429631 -2418,2418,H151I,-0.091118696,0.042732436,-0.004307714,0.054077597000000005,0.007014468,-0.009626771,-0.040491866,-0.141745525,-0.0018573620000000002,0.006585955,0.078878916,-0.012686722,0.0040712940000000005,0.010000399,0.098154794,0.001941657,0.012087278,1.4606517890000001,2.864537266,-3.177519615,-3.546555328,-3.824728447,-3.588412224,-2.858729332,-2.069172745,-3.86348977,-1.9206402280000001,-1454.9058520109393 -2419,2419,H151K,-0.115419731,0.020234528,-0.065171224,-0.005745355,0.007145896999999999,-0.015184435,-0.062193873,-0.16864558899999998,0.055915981,-0.055918003,0.09638705800000001,-0.073744278,-0.056598169000000004,-0.048055698,0.036564989,-0.028823177999999998,0.043114972,1.3808795530000002,2.5726562790000003,0.01622829,-0.209568008,-0.30559009600000003,-0.810663803,0.45093084,0.9560325159999999,-1.999887147,0.796016994,-1449.3334344346076 -2420,2420,H151M,-0.084675154,0.032402332,-0.03601272,-0.0008947810000000001,0.04515802,0.018803699,0.002492075,-0.17184238300000002,-0.0049213270000000005,-7.780000000000001e-05,0.064882464,-0.028905156,-0.043120284,-0.027030649,0.025241087000000002,-0.0038073609999999996,0.0941234,1.2452271190000002,2.512020517,-4.272683931,-4.512946747,-4.075936508,-4.390445129,-4.570787605,-3.813303665,-4.896618336,-2.977771011,-1455.0501395161264 -2421,2421,H151L,-0.03714882,0.024070078999999998,-0.018514441,0.023054959,-0.024805365,0.060781385,-0.007202656,-0.067094983,0.02129678,0.000404481,0.047735676,-0.045726634,0.008697752,-0.012015828999999999,0.058125747,-0.030168043999999998,-0.019442686,1.329506211,2.632417145,-1.846781851,-2.6581923290000002,-1.5324610140000001,-2.128407913,-1.854939163,-1.059908836,-2.757528375,-1.1084670140000001,-1451.647130346857 -2422,2422,H151N,-0.04167483,0.111773845,-0.00887768,0.057593869000000006,0.079552158,0.015522741000000001,0.059770730999999994,-0.14312039099999999,-0.025132627,0.023678893,0.199868797,-0.013080231999999999,-0.004675128,0.017106575,0.09808116199999999,0.033374576,0.125729739,1.209489535,2.733143689,-2.263015172,-2.250972794,-2.489696518,-3.5878673169999997,-2.049047302,-0.9374919279999999,-3.4801793739999995,-0.295191553,-1448.9849558919668 -2423,2423,H151Q,0.008097306,0.049487545,-0.023534331000000002,0.020552461,0.068242096,0.012247869,0.024699537999999997,-0.008504926,-0.035589159,0.026356982999999997,0.072618106,-0.035769896,-0.011298765,-0.012973296,0.054078217000000005,0.027385938999999998,0.109098253,1.203635836,2.578888789,0.0019400970000000002,0.12589286800000002,0.062662415,-0.164153305,-0.235706337,0.221004845,-2.0399553409999998,0.357678089,-1451.8141664587893 -2424,2424,H151P,-0.10883213900000001,-0.021637302,-0.052757775,-1.106333963,-2.286537924,0.074657818,-0.050747093,-0.166917185,-0.020200868,-0.016304524,-0.02697008,-0.069524175,-0.035991374,-0.838893923,-1.373774003,-2.011578778,-2.561497069,2.143913215,1.526947865,-5.068095193,-4.291822182,-5.608892792000001,-4.753143005,-6.059317397999999,-4.627300591,-5.164181419,-2.9374735889999997,-1464.0889697619714 -2425,2425,H151S,-0.038089448,0.026742527000000002,-0.03233603,-0.009772832,0.010206805,-0.013619527,0.011139602,-0.087318497,-0.00040807,0.001291514,0.052193539000000004,-0.042432608,-0.022239452000000003,-0.028454668,0.008909005,-0.014489888999999999,0.034903499,1.170104237,2.370551146,-2.427499944,-2.709459015,-2.572771545,-2.807108597,-2.464512917,-1.583647644,-3.764147701,-0.528210525,-1447.456056968309 -2426,2426,H151R,-0.031582805,0.013201901,-0.03382406,0.00759869,0.02308135,0.026862902999999997,0.005308768,-0.068474378,-0.039748774,-0.01149753,0.037901331,-0.050839445,-0.016808675,-0.020141915,0.035339294,0.010763435,0.035399264,1.155493763,2.649198214,4.344642407,4.331341728,4.692338112,5.363595131,3.47327803,3.862659035,-0.198878904,2.545079743,-1468.5037851268426 -2427,2427,H151T,-0.07090395099999999,0.023371469,-0.045426524,0.028249187999999998,0.016665056,0.019913848,-0.009841546,-0.131966355,0.028475753,-0.004828746,0.051571683,-0.056941548,-0.033911500000000004,-0.017645631000000002,0.074144006,-0.009570299,0.04290041,1.27048636,2.589348045,-2.731234155,-2.628215569,-2.418522293,-2.816511993,-3.382757095,-2.410163826,-3.317627615,-0.6360176679999999,-1452.5544085954316 -2428,2428,H151W,-0.10375080199999999,0.020314651,-0.043713862,-0.002036515,-0.034528765,0.018080151000000003,-0.066175233,-0.141326371,0.077846187,0.011673413999999998,0.028955887000000003,-0.050398819000000004,-0.037028905,-0.023713847000000003,0.019640816999999998,-0.017600803,-0.051456725999999994,1.299376244,2.5596218619999997,-4.98897953,-4.91882827,-4.922684837,-5.326031517,-4.991850777,-4.7855022510000005,-6.305067339,-4.257562887,-1462.6190205933526 -2429,2429,H151V,-0.053295484000000004,0.00728024,-0.041171397,0.009840624000000001,0.001629947,0.024982499999999998,-0.039419472000000004,-0.067171495,0.024944842999999998,-0.045989575,0.060550055,-0.08687916,0.004536367,-0.031761713999999996,0.051442960999999995,-0.052323575,0.055583469,1.304107946,2.425258235,-2.983877829,-3.3528355789999997,-3.5123106689999997,-2.634823601,-3.164674255,-2.254745041,-4.354236141,-1.409153789,-1456.8615300403908 -2430,2430,H151Y,-0.085886227,0.019180636,-0.057377683,0.002261466,0.007816278000000001,0.039328978,-0.029727088999999998,-0.142045364,0.012390965,0.025417258999999998,0.012944012,-0.059040362,-0.055715003,-0.015163941,0.019686873,-0.020771071999999998,0.036403628,1.39417163,2.600260542,-5.068441486,-5.341093628,-5.749372527999999,-5.767723907000001,-3.9787299039999997,-4.50528746,-5.564242997999999,-3.272516818,-1462.2058642227203 -2431,2431,N152A,-0.011433482,-0.04994268,-0.022527537,0.010882838,-0.039471637999999996,-0.043359589000000004,-0.013351196000000001,-0.009515767,0.011803313000000001,-0.020344468,-0.079540892,0.007183927,-0.052239,0.014283019,0.007482656,-0.00504614,-0.073897135,1.543610422,3.106887046,0.768850725,0.39561691299999996,-0.024943427999999997,2.089611641,1.223895515,0.160072983,-2.1336775340000003,1.565206209,-1461.8165731974877 -2432,2432,N152C,0.015336401999999999,-0.034951536,0.003714497,0.043710741,-0.154368375,-0.035345216,0.022171002000000002,0.008501801,-0.0034580270000000002,-0.020414465,-0.049488606,0.040376736,-0.032947743,0.02746781,0.05995367099999999,-0.09915880099999999,-0.20957794800000001,1.3695411290000001,2.402694163,-3.849361131,-3.6189486239999997,-4.719303406,-3.1568600539999996,-3.477322762,-4.274370811,-6.1579855729999995,-3.7305060739999996,-1455.2096244227141 -2433,2433,N152E,-0.033090503,-0.062174784000000004,-0.014990673999999999,-0.056213158,-0.011654538999999998,-0.124114048,-0.034000033,-0.032180972,0.073786214,0.13939483,-0.263744397,0.099498188,-0.129479536,0.10710552400000001,-0.21953183899999998,0.035778282,-0.05908736,1.140601244,2.8972879000000002,0.65273307,1.161050987,0.217034134,1.165320793,1.4308720469999998,-0.71061261,-2.7950094780000003,1.83743699,-1460.3066480327398 -2434,2434,N152D,0.054758835,-0.021588859,-0.008413435,0.049488544,-0.030300907999999998,-0.049508684000000004,0.068661483,0.040856187,-0.038500776,0.042091355999999996,-0.085269073,0.012942122,-0.029768991,0.054255315,0.044721772,-0.00028289200000000003,-0.060318924,1.246123487,2.69232746,0.168927968,0.495791855,-0.647542694,0.38547754700000003,1.5538800659999998,-0.9429669340000001,-2.3323221419999998,1.216213012,-1463.1900814189576 -2435,2435,N152G,-0.027611339,-0.053810582999999995,-0.033734201,-0.011688862,-0.066780817,-0.02528902,-0.015056561000000001,-0.040166116,0.05281695,-0.018405658000000002,-0.08921550800000001,-0.008719329,-0.058749072,-0.017047863,-0.006329861,-0.041435449,-0.092126185,1.178655953,2.382238516,0.7683725809999999,0.304195663,1.1831388170000001,1.2090421679999999,1.248031105,-0.102544846,-1.522460535,1.25857957,-1464.0894137383439 -2436,2436,N152F,-0.069340403,-0.063699459,-0.020861878,-0.000530987,-0.108405949,-0.004646525,-0.074917873,-0.06376293200000001,0.001342488,-0.043669828,-0.083729089,0.002588175,-0.044311931,-0.012031087,0.010969113999999999,-0.090938665,-0.125873232,1.808125749,2.84446623,-2.806405893,-3.024840897,-3.307155266,-2.054990761,-2.186311089,-3.458731453,-4.474009247,-2.455259395,-1463.770202754531 -2437,2437,N152I,0.030775419,0.012550933,-0.020116009,0.029934289,-0.079239517,-0.013439395,0.030858986,0.030691852000000002,0.006984069,0.020539744,0.004562121,-0.028855479,-0.011376539,0.012476103,0.047392474000000004,-0.067062023,-0.09141701099999999,1.382262972,2.480259362,-3.087599748,-3.1140351330000002,-3.7666657710000004,-1.9789742430000001,-2.7979511180000003,-3.780372475,-5.141970217,-2.588873713,-1462.029484855011 -2438,2438,N152H,0.045923381,-0.001280085,0.004123616,0.029810105,-0.024670175,-0.050381217,0.044559213,0.047287549000000005,0.019882567,0.008278591,-0.010838761,0.010343187,-0.002095956,0.026832796000000003,0.032787414,-0.007348808,-0.041991542,1.222447558,2.570798611,-1.030588254,-1.248663322,-1.69190377,-0.17603438600000001,-0.277528732,-1.758811058,-3.288689088,-1.350892114,-1458.8177205072716 -2439,2439,N152K,0.003158785,0.013774008999999999,0.008786061,0.051147214,-0.009286896999999999,-0.029543416,0.017465254,-0.011147685,0.010718233999999998,0.042928201,-0.015380183,0.091377963,-0.073805842,0.08538343,0.016910997,0.02493349,-0.043507283,1.096146598,2.6734270319999998,1.7153535640000002,1.620443321,1.3737128980000002,2.3932113719999997,1.749741745,1.439658485,-0.214358098,1.170426945,-1463.1931196018122 -2440,2440,N152M,0.044283533,-0.030662073999999997,0.024355115,0.069174231,0.054737747999999996,-0.03740111,0.050431671,0.038135395,0.144009991,-0.056073295,-0.005250851999999999,0.024382131,0.024328098,0.032262127,0.106086335,0.026008329,0.08346716700000001,1.0430483990000001,2.559148394,-2.381776381,-2.493438545,-2.984979553,-1.085790207,-1.8693703380000002,-3.475303261,-4.871930773,-1.957744891,-1461.069513257593 -2441,2441,N152L,0.013555494,-0.023193484,0.004188682,0.04564749,-0.023505812,-0.028525767,0.026038891,0.001072097,0.039961961000000004,0.027063992999999998,-0.07345096,0.060467945,-0.052090582,0.048321959000000005,0.04297302099999999,-0.019168137,-0.027843487000000004,1.148125972,2.50576595,-1.35959268,-1.201248047,-2.26440416,0.038652626,-0.600534775,-2.770429047,-3.2987885439999998,-0.828496942,-1458.7673363788053 -2442,2442,N152Q,-0.042668194000000007,-0.052723915,-0.024074885,0.023678823999999998,-0.018047743999999998,-0.027222355,-0.044720729,-0.040615658,0.084737964,-0.017646029,-0.087801801,0.036199114,-0.084348884,0.057817165,-0.010459518000000001,-0.024098985,-0.011996503,1.1219573870000001,2.500446185,1.468100661,2.15658979,1.116757072,2.12848365,1.2436436309999999,0.69502916,-1.300696584,0.870261335,-1462.6925188992172 -2443,2443,N152P,-0.017327548999999998,-0.013641998,-0.028842046,-0.811814577,-2.12322271,0.031354982999999996,0.026861332,-0.06151643,0.024250056000000002,0.003780999,-0.031064995,-0.012119708,-0.045564384000000006,-0.33849241799999996,-1.285136736,-1.902535715,-2.343909704,1.466137834,1.363625619,-5.075810951,-5.29488269,-5.314871552,-4.264208733,-4.653109894,-5.851981887999999,-7.4333293639999996,-6.615121461,-1456.2926908577792 -2444,2444,N152S,0.020134507,-0.014112863,-0.013367666,0.027804474,-0.015036708999999999,-0.013167468,0.049892985,-0.009623971,0.014690271999999999,-0.013324997,-0.014900728,0.0047511129999999995,-0.031486444,0.013550214,0.042058733,-0.00953398,-0.020539437,1.099033345,2.603512733,1.931280203,1.220965279,1.990486961,2.690310287,2.1436993330000003,1.610939156,-1.4552245519999998,2.4531232309999997,-1463.0829229853116 -2445,2445,N152R,-0.0037177720000000003,-0.023367294,-0.018911358,0.026811125,0.021453871,-0.016292373,0.001525304,-0.008960847,-0.004586294,-0.013420142,-0.033314445,-0.000501654,-0.037321062,0.011024178,0.042598072,0.002115921,0.040791821,1.1775332090000001,2.56891234,0.98794026,1.7498448030000002,-0.038460495,2.0215810469999997,1.561235016,-0.354499069,-2.5448919169999997,1.2293010229999999,-1455.8979842206463 -2446,2446,N152T,-0.020735158,-0.023301345,-0.027087315,0.02854487,-0.035577057,-0.005014857,0.00903169,-0.050502005999999995,-0.044922233,0.018373623999999998,-0.06497631400000001,0.004267882,-0.058442510999999996,0.043157804,0.013931936,-0.032509479,-0.038644634,1.08978692,2.3610760490000002,0.645357855,0.8170365909999999,0.21410801699999998,1.9276523209999998,0.711049278,-0.443056931,-2.262719106,0.866706216,-1461.4688237966038 -2447,2447,N152W,0.031493919,0.014761498999999999,0.018358901,0.011484901,-0.079932065,-0.004126793,0.034248874,0.028738964,0.058657192999999996,0.036962453,-0.007439455,-0.015728729,0.05244653,0.015170952,0.007798849,-0.06791575700000001,-0.09194837300000001,1.443425681,2.567130944,-3.225853453,-3.2218274310000004,-3.720396935,-2.719429031,-2.519909088,-3.947704781,-5.0712110269999995,-2.697781782,-1455.6276153791696 -2448,2448,N152V,0.020876126000000002,-0.038652517000000004,-0.014410437,0.025214737999999997,-0.04207795,-0.047828653,0.019783987,0.021968263999999998,0.01614578,-0.035985595,-0.041319439,-0.018656864,-0.01016401,0.00841658,0.042012895,-0.064068489,-0.02008741,1.321427578,2.414619047,-2.657493413,-2.9007463760000003,-3.221209946,-1.407447266,-2.2718316730000003,-3.4862318039999995,-4.745565372,-2.0909427519999997,-1461.1212887708098 -2449,2449,N152Y,0.0017425129999999998,-0.088085441,-0.039997519,-0.005133493,-0.111851337,-0.10883629,-0.020533333,0.024018359,0.056415895,-0.019722889,-0.15644799199999998,-0.028904932999999997,-0.051090104000000004,0.013821521000000002,-0.024088506000000003,-0.070463882,-0.15323879199999998,1.448219973,2.5538123269999997,-4.094043797,-4.05106395,-4.7394282610000005,-3.596618172,-3.6128402860000004,-4.4702683180000005,-6.50670837,-4.0163065730000005,-1461.7251958358102 -2450,2450,M153A,-0.000893157,-0.04853888,-0.024352192,-0.01493279,-0.068678108,0.043481003,0.015309604,-0.017095917,0.013322961000000001,-0.09293362599999999,-0.0041441329999999995,-0.074674269,0.025969886,-0.041686672,0.011821093000000001,-0.120122695,-0.017233521,1.4081125909999999,2.282057485,0.21192924300000002,0.437196915,-0.090135231,0.575755928,-0.23217009,0.368998695,-1.746891411,-0.023798938999999998,-1451.8713104571216 -2451,2451,M153C,0.015455917,-0.074472176,-0.02530344,-0.003911755,-0.06451559700000001,0.043405187000000005,0.042595897,-0.011684064,0.01242164,-0.106103374,-0.042840977,-0.070646215,0.020039335,-0.031979185,0.024155676,-0.107687097,-0.021344096,1.568085565,2.44574677,-3.1864876939999998,-2.263960205,-2.9786208189999996,-2.346251724,-3.9747441180000003,-4.368861603,-4.6490666560000005,-2.505589322,-1462.9276131209917 -2452,2452,M153E,-0.045572932999999996,-0.07537656200000001,-0.079731778,-0.057863318,-1.375037549,0.0033391590000000004,-0.012520982,-0.07862488299999999,0.029383778,-0.08652353300000001,-0.064229591,-0.105541976,-0.053921579000000004,-0.070869834,-0.044856800999999995,-1.299176098,-1.450899,0.973432174,1.3615191530000001,-3.334168483,-3.4092448810000002,-2.685111885,-2.718372231,-3.225838646,-4.632274773,-4.985266744,-2.71249938,-1458.8324086463545 -2453,2453,M153D,-0.017972121,-0.12088988099999999,-0.034838121,-1.314663933,-3.100132561,0.029438235,0.035049322,-0.07099356400000001,0.015850057,-0.116235209,-0.125544553,-0.09882889800000001,0.029152657000000002,-1.020945203,-1.608382662,-2.755195666,-3.445069456,1.190455422,0.849291638,-5.0973537339999995,-4.35689151,-4.215814331,-4.369893982,-6.259194762999999,-6.284974083,-6.465352212000001,-4.622148813,-1455.6558287048247 -2454,2454,M153G,0.00011674799999999999,-0.070426135,-0.065525482,-0.039725743,-0.718774831,0.043237013,0.044669713,-0.044436217,0.061309338,-0.110951718,-0.029900551,-0.110731119,-0.020319845,-0.078920698,-0.000530787,-0.6061763720000001,-0.8313732890000001,1.4066612040000002,1.7004063130000002,-3.8582785339999996,-3.313970657,-3.250262222,-3.220343544,-5.242351799,-4.264464447,-5.205583121,-2.46660317,-1457.5043586674146 -2455,2455,M153F,0.031660399,-0.032419965,-0.044628695999999995,-0.01831842,-0.20109806300000002,0.004587052,0.078264185,-0.014943386999999999,-0.040803012,-0.056522775,-0.008317155,-0.072701204,-0.016556187,-0.031902299,-0.004734541,-0.22128372,-0.18091240600000003,1.4531365019999998,2.105537494,-3.165231651,-3.6596690219999997,-2.100636566,-1.939097076,-4.7180811160000005,-3.408674477,-3.383627142,-0.8796904320000001,-1459.459447318688 -2456,2456,M153I,-0.02279005,-0.069966051,-0.05886631,-0.025849927999999998,-0.023306261,0.010288365,-0.00036024099999999997,-0.045219857999999995,0.063780595,-0.075334311,-0.064597791,-0.08592738400000001,-0.031805236,-0.023915812,-0.027784044,-0.032520619,-0.014091903000000001,1.3673579130000002,2.482879168,2.582267645,3.1331363910000003,2.853251694,2.396836319,2.380410156,2.147703667,-1.27754249,1.526494021,-1469.5461704828776 -2457,2457,M153H,-0.030460322,-0.06442835200000001,-0.064770973,-0.051160113,-0.558468368,0.012488744,0.021857293,-0.082777937,0.013788284,-0.078836705,-0.050019997999999996,-0.043050362,-0.08649158300000001,-0.042793229,-0.059526997000000005,-0.42259626899999997,-0.6943404670000001,1.266592186,1.714353044,-2.50647159,-0.550963654,-1.5793248519999998,-1.2419989470000001,-3.914439743,-5.245630753,-3.932681324,-0.624151115,-1464.5904191308655 -2458,2458,M153K,0.000344509,-0.063911195,-0.046524015999999994,-8.82e-05,-1.354327293,0.016966521000000002,0.060000798,-0.05931178,0.09397558,-0.076633007,-0.051189383,-0.054288727,-0.038759305,0.0056642969999999996,-0.005840665,-1.151225158,-1.557429427,0.885738327,1.3626752930000001,-2.196114149,-0.935360588,-2.324760757,-1.56796151,-1.170633324,-4.981854568,-4.456458958,-0.435720121,-1468.8380184299313 -2459,2459,M153L,0.021723107000000002,-0.048140757,-0.042822708,-0.018348258,-0.047138285,-0.002502523,0.041060121,0.0023860920000000002,-0.027541573,-0.082715873,-0.013565641000000002,-0.09043751900000001,0.004792104,-0.036401733,-0.000294783,-0.091721595,-0.002554974,1.414371733,2.342971976,0.829538179,0.194063995,1.34887043,1.328326263,0.632747253,0.643682953,-2.055258549,2.3552972569999997,-1467.4311985564418 -2460,2460,M153N,-0.059078343,-0.100293009,-0.051161989000000005,-0.046712507,-0.26143853300000003,0.033236719,-0.030480956,-0.08767572900000001,0.008509433,-0.101656436,-0.09892958199999999,-0.036927277,-0.0653967,-0.03609188,-0.057333133,-0.24538801699999999,-0.277489048,1.3653149269999998,1.992304153,-0.7760457820000001,0.470534561,-0.19487994399999997,-0.589908401,-0.8645747909999999,-2.701400337,-3.2277057630000003,-0.625274569,-1465.951320733875 -2461,2461,M153Q,-0.0013257170000000001,-0.029950998,-0.040994471,0.00935391,-0.266883514,-0.003264083,0.022920625,-0.025572058999999998,0.01615808,-0.030272777999999997,-0.029629217000000003,-0.044988329,-0.037000612999999995,0.009399926999999999,0.009307892,-0.24108940899999998,-0.292677619,1.287016148,1.9182968619999998,-1.5684473280000002,-1.309676872,-1.7117624740000001,-0.91107859,-0.772566887,-3.137151817,-3.494837563,-0.711963173,-1463.2342946426943 -2462,2462,M153P,-0.045457594000000004,-0.5864100839999999,-1.689459473,-2.140285318,-2.742925642,0.067042502,0.012818969,-0.103734157,0.031219079,-0.36559740799999996,-0.8072227590000001,-1.671050111,-1.7078688340000001,-2.11601345,-2.164557186,-2.737365795,-2.748485488,2.719060063,0.964372197,-5.153808401,-4.427905685,-5.026608253,-4.218106033,-6.119202262999999,-5.977219772000001,-6.6298604039999995,-4.9961512,-1457.3265191772953 -2463,2463,M153S,-0.003965683,-0.065935489,-0.039175656,-0.032096354,-0.11301312699999999,0.020120345,0.036870812,-0.044802177,0.010467666,-0.097969296,-0.033901682,-0.0646766,-0.013674711,-0.031692198,-0.03250051,-0.11746129300000001,-0.108564961,1.381479289,2.282366327,0.6655457610000001,1.37475576,0.477734528,0.79950087,0.667361282,0.008376366,-2.363289409,-1.2466061290000001,-1457.7117135738954 -2464,2464,M153R,-0.031284621,-0.08109103599999999,-0.052212340999999995,-0.019139454,-1.312866025,0.040285937,0.01190677,-0.07447601200000001,0.008397863,-0.08439371300000001,-0.077788358,-0.073031365,-0.031393317000000004,-0.037402242999999995,-0.000876664,-1.125351386,-1.5003806640000001,0.819115143,1.35732959,-3.684900705,-2.412994217,-3.313148895,-2.2555914,-3.4791816019999997,-6.96358741,-4.428052127,-1.56020962,-1462.1847080504522 -2465,2465,M153T,-0.0036354459999999996,-0.02968158,-0.033427214,-0.012525733999999998,-0.079235997,0.042771225,0.019113598,-0.02638449,0.014957648,-0.06848711099999999,0.009123952,-0.046797418,-0.020057009,-0.038788502,0.013737033999999999,-0.12326215900000001,-0.035209834,1.310114585,2.176296874,2.763943616,3.3077445219999997,1.596822144,3.209587875,3.24173365,2.4638298869999997,-0.9479325559999999,-0.6010921379999999,-1463.8897235877812 -2466,2466,M153W,0.052658416,-0.067811038,-0.039329866,-0.0062506919999999995,-0.063727216,-0.0032316259999999996,0.072304735,0.033012096,-0.032091377000000004,-0.124515225,-0.011106851000000001,-0.11564716300000001,0.036987432,-0.046808665,0.034307281,-0.143930724,0.016476293,1.534922162,2.301276998,-4.119347665,-2.434812645,-3.195022751,-2.828325371,-6.667254112,-5.471323448,-4.872816781,0.352898765,-1456.9777903426439 -2467,2467,M153V,0.038254988,-0.066628092,-0.053315928,-0.011454778999999998,-0.099218971,0.004970502,0.061975247000000004,0.014534728,0.004978939,-0.108258414,-0.024997769,-0.088137456,-0.0184944,-0.058090225999999995,0.035180668,-0.119767237,-0.07867070400000001,1.4629270730000001,2.306117247,-0.44197549700000005,-0.425092422,-0.55407206,0.249824173,-1.239437469,-0.241099709,-2.719991605,-0.399499941,-1466.0746911270544 -2468,2468,M153Y,0.007096401,-0.109894964,-0.063498895,-0.035205286,-1.0359273359999999,0.010788698999999999,0.05474992,-0.040557117999999996,0.022754851,-0.146001897,-0.07378803,-0.09367465300000001,-0.033323136,-0.044880357999999995,-0.025530213,-0.76275478,-1.309099891,1.01803052,1.4617097559999999,-4.124407455,-2.3706070180000003,-2.9218892210000003,-2.8653538210000002,-5.803723366,-6.660463852,-4.632548685,-1.209919585,-1461.6308692675084 -2469,2469,G154A,-0.069519442,-0.014709345,-0.025238107000000003,-0.027580141000000002,-1.237814556,-0.008313525,-0.053914672999999996,-0.08512421,-0.012238958999999999,0.015340573,-0.044759263,0.010110326,-0.06058654,0.000193681,-0.055353963,-0.98456598,-1.491063131,0.638010402,1.348888865,-6.699757701,-6.957807602000001,-6.17841069,-5.970554924,-6.608040634,-7.783974655,-7.070465463,-4.605993106000001,-1453.8788531315513 -2470,2470,G154C,0.061699138,0.030642077,0.028610204,0.011641261000000002,-1.748269181,0.072641281,0.08388053200000001,0.039517743,-0.062367747,-0.006077608000000001,0.06736176099999999,-0.072748845,0.12996925199999998,-0.068343878,0.09162639999999998,-1.594745223,-1.9017931380000002,0.897040265,1.330623285,-10.67275105,-10.64373613,-10.65413329,-9.998270927,-10.34248991,-11.725125,-10.23801718,-9.799455849,-1451.6181798428297 -2471,2471,G154E,-0.030818934,-0.008143799,-0.012085321999999999,-0.023197002,-0.123728146,-0.007812686999999999,-0.013168187,-0.048469680999999994,0.004011315,0.042298817999999995,-0.058586415999999995,-0.01001445,-0.014156193000000001,0.038065057,-0.08445906,-0.091883591,-0.155572701,1.165170396,2.280433979,-6.282221382,-6.694281448,-6.303623459,-5.689124382,-6.076457695,-6.647619926,-7.424419403,-4.709355358,-1459.9947803998366 -2472,2472,G154D,0.028673993,0.029727701000000002,0.06889425099999999,-0.0035245259999999996,-0.095326544,-0.018887621,0.009609884,0.047738101,0.062725365,0.029816371,0.02963903,0.004663378,0.133125123,-0.015973317,0.008924266,-0.07826896900000001,-0.112384118,1.37018417,2.384313874,-4.050534453,-3.836264709,-4.300890121,-3.9506298369999997,-3.816650764,-4.3482368319999996,-4.2033275119999995,-3.7532631910000003,-1460.8085111104883 -2473,2473,G154F,-0.126024532,-0.013778468,-0.019319133,-1.251859222,-2.091244835,0.04696338,-0.113748899,-0.138300165,0.067680395,0.009959789,-0.037516724,-0.010243381999999999,-0.028394884,-0.7582278920000001,-1.745490552,-2.3373581480000003,-1.8451315209999999,0.766748545,0.7910421240000001,-10.98741669,-11.11834149,-10.31445856,-9.640827599,-10.55477,-13.308685800000001,-9.160623625,-7.332861106,-1454.6693874588236 -2474,2474,G154I,-0.070364444,-0.004059375,-1.00798015,-2.035501323,-2.6520505,0.049201274,-0.017330149,-0.12339873900000001,-0.189444115,-0.0031536909999999997,-0.004965058,-0.616295215,-1.399665084,-1.475491888,-2.595510758,-2.419893036,-2.884207963,2.3835124469999998,1.318876642,-9.951609966,-10.59664423,-9.216638466000001,-8.706580681,-9.356460579,-11.88172587,-8.440169982,-5.879278424,-1451.9626743174158 -2475,2475,G154H,-0.07477357400000001,-0.045542659000000006,-0.035083726,-0.032815073,-0.947665442,0.070243395,-0.04617320900000001,-0.10337393800000001,-0.025136331,0.0015584120000000001,-0.09264373,-0.069752551,-0.00041490099999999996,-0.027713879,-0.037916266000000004,-0.65467167,-1.2406592140000001,0.7915633540000001,1.4189854469999998,-7.105425505,-7.775099487,-7.016882172000001,-5.857788467000001,-6.436165871,-8.441191528,-7.172455042,-4.949104558,-1454.908568491228 -2476,2476,G154K,-0.058742891,0.02000366,-0.047415079000000006,-0.05681420400000001,-1.2103183640000001,0.060809797,-0.008873522,-0.108612259,0.11546301199999999,0.002450187,0.037557132,0.01440133,-0.109231488,0.000478917,-0.11410732400000001,-1.05607221,-1.3645645180000001,0.627515581,1.344324305,-5.645068147000001,-7.2138809429999995,-4.736698204,-3.859962326,-6.100290604,-6.3145086589999995,-6.373937817000001,-3.99748434,-1457.9027790855616 -2477,2477,G154M,-0.039382187,0.11502716199999999,0.045672845999999996,-0.129232834,-2.1232713480000003,-0.007799355,-0.054053493,-0.02471088,-0.019291095,0.140708572,0.08934575199999999,0.046810280999999995,0.04453541,0.030206096,-0.288671764,-1.699524887,-2.547017809,0.6763988470000001,1.309820897,-10.52694867,-10.9298212,-10.24547222,-9.66501725,-9.640929291,-12.1535034,-9.138233117999999,-7.258488053,-1453.2605986758135 -2478,2478,G154L,-0.056807799000000006,0.026581221000000002,0.000236938,-0.924058356,-1.8288068819999999,0.038265837999999996,-0.03520246,-0.078413138,-0.020302824,0.021261897000000002,0.031900543999999996,-0.086890767,0.08736464199999999,-0.41032844799999996,-1.4377882640000001,-1.9179268369999998,-1.7396869259999999,1.615314093,1.3897826030000002,-10.38756556,-10.76138893,-10.04543601,-9.787281265,-9.702346558,-11.64137503,-8.974184228,-6.70808671,-1450.5746596422978 -2479,2479,G154N,0.037178341000000004,0.057117967,0.043187729,-0.025664267999999997,-0.235432728,0.043901895999999996,0.009182891,0.06517379,-0.01424616,0.031377469,0.082858464,0.01828014,0.068095318,-0.022835815,-0.02849272,-0.126653285,-0.344212171,1.310563981,2.1667946209999998,-5.402220216,-5.988703812000001,-4.882593849,-4.824374298,-5.358210495,-5.957218628,-6.313006516000001,-3.9358401819999997,-1455.4474306278862 -2480,2480,G154Q,-0.04880471,-0.011037841000000001,-0.020479156999999998,-0.06745567,-0.544538125,-0.000283455,-0.049663439000000004,-0.04794598,-0.050430040999999995,0.005700780999999999,-0.027776462999999998,-0.0019553120000000003,-0.039003002,-0.049079042999999996,-0.08583229699999999,-0.436592669,-0.65248358,1.3186107009999999,1.763316696,-6.921066617999999,-7.915036606,-6.447889732,-5.799887093,-6.45945224,-7.983067421,-6.906009397999999,-4.878748221,-1455.4473515655845 -2481,2481,G154P,-0.064134605,-0.017827902,-0.000721582,-1.128028785,-2.117260163,0.041383855,-0.029303851000000002,-0.098965358,-0.0061409509999999995,-0.024102967000000003,-0.011552837,-0.02477055,0.023327387,-0.645319526,-1.610738043,-1.817246556,-2.417273769,1.9822679980000002,1.533326688,-8.871445451,-9.194732903,-8.282525299,-8.028753304,-8.425364532,-10.42585122,-8.238064256,-5.758034822000001,-1455.1586613771506 -2482,2482,G154S,-0.02969886,0.040798173,0.011812035,-0.042061182999999995,-0.952716773,0.027383652999999997,-0.002065135,-0.057332585,0.060180357999999996,0.024324271,0.057272074000000006,-0.015292954,0.038917024,-0.040315154,-0.043807211,-0.737836222,-1.1675973240000002,0.92163243,1.42205504,-6.86839415,-7.511909697999999,-6.646678291000001,-6.1553453220000005,-6.501949553999999,-7.526087883,-6.557071093999999,-4.960697881000001,-1455.6523809744976 -2483,2483,G154R,-0.019074487,-0.007897897,-0.004886792,-0.007619483000000001,-1.558836255,0.024284791,0.006156223000000001,-0.044305196,-0.034458644,0.002096008,-0.017891801000000002,-0.029708201,0.019934618,0.033642562,-0.048881527,-1.407021784,-1.710650726,0.484834256,1.313717185,-6.502336949,-7.334469055,-6.513335402999999,-5.610071838,-5.935332291,-7.118476157999999,-6.657355317,-4.71675294,-1455.2445002608001 -2484,2484,G154T,-0.062763307,-0.038722972,-0.034677977,-0.441178694,-1.714924849,0.020651929,-0.041550035,-0.08397657900000001,-0.014438592,-0.019416766000000002,-0.058029177,-0.075559823,0.006203869,-0.180812372,-0.701545016,-1.8150401440000001,-1.6148095530000002,1.2556072059999999,1.3464179809999999,-9.046001777999999,-9.161574768,-8.854704681,-8.343149666,-8.588078156,-10.28250162,-8.363718524,-6.3006191,-1453.600190514233 -2485,2485,G154W,-0.010926739,0.085994918,0.004156222,-1.457664516,-2.49126502,0.0017444189999999999,-0.025393846,0.003540368,0.019962204,0.024786896,0.147202939,-0.060702926,0.06901536900000001,-1.21764196,-1.697687071,-2.151047724,-2.831482315,2.258185993,1.469591825,-10.85012607,-11.05415214,-10.27889148,-9.966582939,-10.69271499,-12.25828883,-9.659008957000001,-8.055785955,-1454.9130226643756 -2486,2486,G154V,-0.171445638,-0.004294180999999999,-0.10647947099999999,-1.056478483,-1.669103351,0.015864218,-0.059711802,-0.283179474,-0.056097549000000003,-0.028923085,0.020334724,-0.11416792699999999,-0.09879101400000001,-1.338920343,-0.774036622,-2.290054874,-1.048151827,1.034825432,0.7547778470000001,-9.381235043,-9.859010956,-8.490148102000001,-8.257165894,-9.212892258,-11.08695801,-7.680342582000001,-4.759363595,-1454.4750636639073 -2487,2487,G154Y,-0.031534836000000004,-0.019082992,-0.033905889,-0.6687876460000001,-2.3250405130000003,0.045010975,-0.03696074,-0.026108932,0.051832508,-0.13088909199999998,0.092723109,-0.10985722699999999,0.04204545,-0.35941440700000005,-0.978160884,-1.932204484,-2.7178765410000003,1.5468607669999999,1.373043656,-11.29682764,-11.10377769,-11.30934724,-10.19146714,-11.07056756,-12.80897854,-9.512232739,-7.853201445,-1453.443710763473 -2488,2488,D155A,0.003981678,-0.20967196800000001,-1.448112198,-2.198496364,-2.933485535,-0.0013367189999999999,0.036747615,-0.02878426,-0.043573245999999996,-0.133591914,-0.285752022,-1.475427345,-1.42079705,-2.092330415,-2.304662312,-3.142323272,-2.724647797,1.0188200920000001,0.07359441,-9.207470869,-10.23106146,-9.923379257,-8.397717247000001,-10.11960451,-7.365591873,-6.909303913,-2.1238134019999997,-1444.3604418160394 -2489,2489,D155C,0.00015561,0.011852722,-1.071935327,-2.0017231509999998,-3.234446418,-0.000157991,0.012187513,-0.011876293999999999,-0.053970504,-0.02253401,0.046239454000000006,-0.953059836,-1.1908108179999999,-1.8004118269999998,-2.203034475,-2.920985758,-3.547907077,2.2737015069999997,1.020350433,-12.89184395,-14.16661003,-14.05482278,-12.16167262,-13.00244463,-11.07366968,-8.609268173,-2.630212658,-1451.7349532619119 -2490,2490,D155E,0.036956696000000004,0.013681047,0.05328934900000001,-1.192240985,-1.954996729,-0.055472457999999995,0.090595774,-0.016682382,-0.043791933,-0.08474568199999999,0.11210777599999999,-0.0033517029999999997,0.10993039999999998,-0.676418237,-1.7080637330000001,-1.633135365,-2.276858093,2.234129801,1.747693142,-8.345086324,-9.666049606,-7.976600433,-7.096618294,-9.189830062999999,-7.796333221,-8.45181249,-5.876338106,-1458.6935053244233 -2491,2491,D155G,-0.006902624,-0.500754898,-1.7094024909999999,-2.146929863,-2.9421224969999997,-0.000832541,0.028717602000000002,-0.04252285,-0.011127159,-0.392071916,-0.60943788,-1.6523558459999999,-1.766449135,-1.967685713,-2.326174012,-2.690319635,-3.1939253589999996,2.814822781,1.091849908,-10.86448262,-11.08599307,-11.25151942,-10.26652254,-11.75585658,-9.962521469,-8.082743788,-3.684269925,-1446.9884644574486 -2492,2492,D155F,-0.091927257,-0.7010173959999999,-1.902495431,-2.137297715,-2.888915262,-0.025752186,-0.05073500400000001,-0.133119509,0.135611382,-0.5381226170000001,-0.863912175,-2.269153578,-1.5358372830000002,-2.116505569,-2.158089861,-2.538109496,-3.239721028,0.225128637,-0.5169833460000001,-13.09466582,-16.37061021,-12.13025437,-12.39965823,-12.92583975,-11.64696652,-8.306901282,-2.1752342369999997,-1455.6117840541992 -2493,2493,D155I,-0.020107639,-0.25738182800000003,-1.56686465,-2.021333282,-2.7729508289999996,-0.156890409,-0.018263916,-0.021951361000000003,-0.153384495,-0.18941422,-0.325349436,-1.480006943,-1.653722357,-2.026328939,-2.016337625,-2.447932866,-3.097968792,3.20779388,1.5496245290000001,-11.56600494,-16.16951958,-11.99451606,-9.124165893999999,-11.3963289,-9.145494263,-6.134750105,-1.4906727780000002,-1447.115024494473 -2494,2494,D155H,0.037100771,-0.5904705960000001,-1.916107755,-2.301425038,-2.7520125889999996,0.054235995,0.073644235,0.000557306,-0.020945121,-0.462183778,-0.718757414,-1.7687157009999999,-2.063499808,-2.014007702,-2.5888423730000003,-2.7366416239999998,-2.767383553,2.897113103,1.084448845,-12.48529931,-13.93601223,-13.27072105,-11.1254513,-12.58130599,-11.51300599,-9.361902147999999,-5.509977217,-1456.7642066441476 -2495,2495,D155K,0.053176642999999996,-0.98425512,-2.154494734,-2.7009216639999996,-3.063463586,-0.007847179000000001,0.08541662,0.020936665,-0.00738334,-1.085416537,-0.883093703,-2.47695925,-1.8320302169999998,-2.3243112409999998,-3.077532086,-2.7459151680000002,-3.381012003,0.44299559299999997,-0.6741532109999999,-13.1565329,-14.24897992,-14.37757285,-12.01937154,-13.81995053,-11.31678967,-10.09707451,-6.396893405,-1460.3663885868154 -2496,2496,D155M,0.009467955,-0.36713878899999997,-1.692735469,-2.301631767,-2.863143693,-0.063756395,0.061422785,-0.04248687599999999,-0.0031605179999999997,-0.246392644,-0.48788493299999997,-1.4830333980000001,-1.9024375390000001,-1.93244538,-2.670818153,-2.7519893160000004,-2.97429807,2.829419601,1.200934606,-12.98772141,-17.06437338,-11.52828859,-12.67088252,-12.3828476,-11.29221494,-7.393728232999999,-2.332778638,-1454.976474895142 -2497,2497,D155L,-0.019981615,-0.806105347,-2.069682387,-2.164859561,-3.537996133,-0.029242232000000003,0.0031966259999999997,-0.043159855999999996,0.044183756,-0.65870638,-0.953504314,-2.176693185,-1.9626715890000002,-2.082037123,-2.247681999,-3.047709095,-4.028283171,0.7013862040000001,-0.479061443,-12.63340408,-17.16984715,-11.27880685,-11.74439623,-11.24773505,-11.7262351,-6.147999936000001,-0.566879436,-1452.1328100669198 -2498,2498,D155N,-0.093440566,0.010202378,-0.0051764720000000005,-0.020706603,-2.020904202,0.026733311000000003,-0.051644987,-0.135236145,0.056993015999999994,0.005052681,0.015352073999999999,0.069958075,-0.080311018,0.07647804700000001,-0.117891253,-1.889193924,-2.15261448,0.6738330790000001,1.301847403,-7.752150746,-8.90872184,-7.910207832,-6.096100044,-8.265003006,-7.580721007999999,-6.752407783,-4.172019344,-1458.2382711628452 -2499,2499,D155Q,0.012764072,-0.065839765,-1.371767942,-2.345130853,-3.309732767,0.04653792,0.049808827,-0.024280682999999997,-0.02622757,-0.057054970999999996,-0.07462455900000001,-1.0946018259999999,-1.648934057,-2.5440138080000003,-2.146247898,-2.965617735,-3.653847798,1.178927973,0.194664295,-12.81461205,-14.30453428,-13.43761433,-11.34158573,-14.14095853,-10.84836738,-9.204608973,-5.713355966,-1454.5653506699018 -2500,2500,D155P,-0.010603617,-0.416758174,-1.780438571,-2.225378252,-2.8765383780000002,0.007792343,0.035763314,-0.056970547999999996,-0.027439132,-0.276614623,-0.5569017239999999,-1.5819493930000001,-1.978927748,-2.140505845,-2.310250658,-2.452965303,-3.300111452,2.63376026,0.9567953140000001,-12.96530857,-14.17996324,-12.290585400000001,-12.38065716,-13.01403873,-12.96129832,-8.54062337,-3.799485948,-1460.9626748827286 -2501,2501,D155S,0.015492007,0.018535481,-1.142645951,-2.0369484819999997,-3.095545636,-0.006296648,0.049851541,-0.018867527,-0.032030609,-0.017832223,0.054903185,-0.8363414290000001,-1.448950473,-1.976503086,-2.097393878,-2.824075745,-3.367015527,2.034027718,0.850867907,-12.0553607,-13.55211435,-12.30636098,-10.99822547,-12.98038394,-10.43971877,-8.999876687999999,-5.648331817000001,-1454.207697009202 -2502,2502,D155R,0.008025082,-1.067685035,-2.004968133,-2.203675495,-3.133164207,0.002900218,0.045609745,-0.029559582,-0.016186597,-0.988828342,-1.1465417279999999,-2.0629506440000003,-1.9469856209999998,-2.0921462230000003,-2.315204766,-2.656417654,-3.609910759,0.31110525,-0.66159675,-13.79767848,-13.93984058,-15.46907941,-13.39449153,-14.32121756,-11.86376332,-9.081220149,-5.1584362960000005,-1459.6420366107486 -2503,2503,D155T,0.02949894,-0.26524323,-1.56228049,-2.21896262,-3.098885595,0.001330697,0.071682359,-0.012684478999999999,0.008483184,-0.17311319100000003,-0.35737326799999997,-1.458564485,-1.665996495,-2.038310236,-2.399615003,-2.380732917,-3.817038272,3.193611821,1.55458012,-11.11340296,-13.17378031,-11.97400218,-9.644707405,-11.39491141,-9.37961351,-8.076540044,-4.355533942,-1452.5011257496662 -2504,2504,D155W,0.014548159,-0.9637630309999999,-2.381639916,-2.344901135,-3.378654397,-0.020864026,0.045844660999999995,-0.016748343,-0.023315359,-0.851832376,-1.075693686,-2.771052718,-1.9922271130000002,-2.317374713,-2.372427556,-3.040008636,-3.717300158,0.383932525,-0.605268424,-15.39729887,-16.81671275,-15.45672027,-14.24447545,-16.2107851,-14.2578008,-9.296415058,-5.717255021000001,-1459.1779303175863 -2505,2505,D155V,0.0306635,-0.36712141600000003,-1.5717429809999999,-2.41396719,-2.95260037,-0.030931757,0.056306691,0.005020308,-0.056937882,-0.313579575,-0.42066325600000004,-1.606677664,-1.5368082969999999,-2.123036436,-2.704897943,-2.8968228810000003,-3.008377859,2.636924189,0.931063943,-11.81194681,-15.08659561,-12.31832057,-9.509256859,-12.72650036,-9.419060669,-7.0874141,-2.353097959,-1445.1318607344292 -2506,2506,D155Y,0.003428328,-0.90280407,-2.231455816,-2.355333726,-2.717875648,-0.029024407000000002,0.057534246,-0.05067759,0.00488892,-0.80382465,-1.00178349,-1.667093586,-2.795818045,-2.116505569,-2.594161882,-2.538109496,-2.8976417989999996,3.2949032760000003,1.3825458130000001,-13.94283793,-17.79250107,-15.6735612,-11.74413324,-13.55660533,-10.94738882,-7.382147565,-2.9841414410000002,-1452.3464279230684 -2507,2507,H156A,0.000790751,-0.014790748000000001,-0.013775121999999999,-0.037463351,-0.069156908,-0.004613879,-0.057818935,0.059400437,-0.020166752,0.017633285,-0.04721478,-0.003919562,-0.023630681,-0.026940812999999997,-0.047985888,-0.045649842,-0.09266397300000001,1.2166231140000001,2.35890501,0.554502347,-0.07855938700000001,0.46700221299999994,1.583049004,0.23050519600000002,0.570514709,-2.86130536,0.72643388,-1463.6916332105175 -2508,2508,H156C,0.020529604,-0.026537667,0.00045868,-0.014785688,-0.10513700699999999,-0.004878065,-0.021974345,0.06303355299999999,-0.065953279,-0.030274909,-0.022800424,0.013275179,-0.01235782,-0.013353091000000001,-0.016218284,-0.12216000099999999,-0.088114013,1.398410085,2.315654605,-3.445492822,-3.462221413,-3.1710599139999998,-3.1056262660000002,-3.3571427839999997,-4.131413734,-6.182460047999999,-3.128659228,-1456.0919555234723 -2509,2509,H156E,-0.037762956,-0.004816341,-0.026718718,-0.047354441,-0.060026062000000005,-0.054687259,-0.054157405,-0.021368507000000002,0.02297905,0.007668952,-0.017301633,-0.016207016,-0.03723042,-0.063252606,-0.031456276,-0.057230477,-0.06282164700000001,1.215770099,2.256930721,1.240963054,0.779028107,1.419941666,1.663993355,0.9075558090000001,1.434296333,-2.406000821,1.173918051,-1459.836835019756 -2510,2510,H156D,-0.025354698999999998,0.016333765,-0.011982939,0.0052694890000000005,-0.030105332000000002,0.009855463,-0.029827015,-0.020882383,0.036641783,0.015788006,0.016879523,-0.006846,-0.017119878,-0.027356377,0.037895355,-0.012306783,-0.04790388,1.202027832,2.511116909,0.844047131,0.855781097,0.901944038,1.536604256,0.8065735629999999,0.11933270300000001,-2.8425578999999996,1.2268215040000001,-1452.5314359171316 -2511,2511,H156G,0.009082244,-0.011025031000000001,-0.023313008,-0.023926916,-0.087994099,-0.006198773,-0.037914523,0.05607901,-0.018761121999999998,0.019916907,-0.041966968,0.008720235,-0.055346251,-0.01456751,-0.033286321,-0.055661071,-0.12032712699999999,1.433653085,2.5771412259999997,0.491278864,-0.565281364,0.3980131,1.437023872,0.50423217,0.68240654,-2.830481761,0.485418576,-1465.4235511235893 -2512,2512,H156F,-0.006938268,0.018674223,0.022466152000000003,0.002627122,0.009488401,-0.030445031,-0.011809397,-0.002067139,0.013887321999999999,0.042887611,-0.005539165,0.053878397,-0.008946094,-0.002073009,0.007327251999999999,0.034957439,-0.015980638000000002,1.132951632,2.714552607,-4.550800871,-3.773891388,-3.639100235,-5.003751221,-4.462842361,-5.874419151000001,-6.578897344,-3.7195397480000003,-1459.97438069107 -2513,2513,H156I,0.009215622,-0.040755232,-0.039775838,-0.052229063,-0.15501738199999998,-0.047527992000000005,-0.027372265,0.045803509000000006,-0.002574528,-0.002109198,-0.079401265,-0.01205723,-0.067494446,-0.04591243,-0.058545695,-0.133365811,-0.17666895300000002,1.402876335,2.227808267,-2.441491991,-2.5159610519999998,-2.093189796,-2.30176265,-2.158230331,-3.1383161239999997,-5.042377543,-1.857423461,-1456.9615125800483 -2514,2514,H156K,-0.067011842,-0.026198547000000003,-0.003989321,-0.003006977,-0.023280442000000002,-0.010627066999999999,-0.061403300999999993,-0.072620382,0.061927561,0.011090227,-0.06348732,0.050448234,-0.058426875999999996,-0.005524669,-0.000489285,-0.019587873000000002,-0.02697301,1.289824957,2.5302698830000003,0.656068959,0.316260223,1.042140244,0.578792274,0.8026498259999999,0.5405022279999999,-2.7150628930000003,1.5061151080000001,-1468.1678363317624 -2515,2515,H156M,0.0273606,0.028954825,0.030014758,0.028995526,0.013323853,-0.012058569,-0.013935778000000001,0.06865697700000001,-0.016352263,0.035718806,0.022190843,0.044585861,0.015443655,0.009531082,0.04845997,-0.020081785,0.046729491,1.145623364,2.5581189269999998,-1.508091638,-2.022221268,-1.3132953490000001,-0.76925148,-1.350404381,-2.085285713,-4.425726222,-1.605335791,-1460.5013434253633 -2516,2516,H156L,-0.008777801,-0.012408425,-0.000862018,-0.018975888,-0.057332812999999996,-0.005969574,-0.04873799,0.031182388999999998,-0.017795249,0.0057529980000000005,-0.030569847,0.031009441000000002,-0.032733476,-0.022130003,-0.015821771999999998,-0.025392261,-0.08927336400000001,1.274597881,2.5472242119999997,-1.296251505,-1.6404417880000002,-0.823567719,-0.9308963929999999,-1.087508385,-1.9988432390000002,-3.908018778,-1.282033687,-1456.2260068808682 -2517,2517,H156N,-0.075020577,-0.023835533,0.035573827,0.000245875,0.000899269,-0.01195473,-0.08249731099999999,-0.06754384299999999,0.006163373000000001,0.005927321,-0.053598387000000004,0.045875765,0.025271889,-0.022665807000000003,0.023157557000000002,0.017778823,-0.015980285,1.229041836,2.626579444,0.842663411,0.338358139,0.791988831,0.9872727659999999,1.7067079319999998,0.388989388,-1.550499162,0.691510105,-1465.1485566305928 -2518,2518,H156Q,-0.035321248,0.006921984,-0.014062934,-0.028171835,-0.03615346,0.005126955999999999,-0.025955205,-0.044687291,-0.031855791,0.017866987,-0.00402302,0.00817785,-0.036303718,-0.022739432,-0.033604237,-0.014396073999999998,-0.057910845,1.2999896229999999,2.6560617509999997,1.1379052920000001,0.0897827,1.406170601,1.286998787,1.36230999,1.5442643809999999,-1.328632852,0.61780149,-1466.1453505069949 -2519,2519,H156P,0.013109826000000002,-0.017643746000000002,-0.008143436,-0.025070528999999998,-0.09989242400000001,-0.011720571,-0.040235192,0.066454844,-0.022467425,0.011110215,-0.046397706,0.0054489809999999994,-0.021735852000000003,-0.028359577,-0.021781481000000002,-0.072473417,-0.127311431,1.3603882040000002,2.4288243,0.796035635,-0.20100656100000003,1.5085631330000002,1.746077835,0.39738263700000004,0.529161133,-2.271937013,0.8126102690000001,-1465.1156330760568 -2520,2520,H156S,0.013185253999999999,-0.023367033,-0.010695743,-0.010834193999999998,-0.044113082000000005,-0.01676159,-0.039234964,0.065605471,0.011227791,0.003577463,-0.050311529,0.011619984,-0.03301147,-0.020846313,-0.000822075,-0.015306662,-0.072919502,1.205719968,2.5626718719999997,0.985202245,0.658240845,1.2812284999999999,1.191527809,0.944833473,0.850180595,-1.7927762999999999,0.93399516,-1466.6221393505111 -2521,2521,H156R,0.00577665,-0.011233411,-0.01747603,-0.038466957999999996,-0.050996883,-0.0024974520000000003,-0.026565659,0.038118959,-0.013646666000000002,0.000573681,-0.023040502999999997,-0.004611149,-0.030340911,-0.042605682,-0.034328233,-0.036668096000000004,-0.06532567,1.310160679,2.512602045,0.6266842579999999,-0.16905329100000002,0.653560593,1.333411972,0.03436438,1.281137634,-2.124178407,1.08640425,-1466.1275780345313 -2522,2522,H156T,0.010346685,-0.009582917,-0.010314859000000001,-0.009820460999999999,-0.026805845,-0.02336808,-0.043461836,0.064155205,0.016238285,0.047302013,-0.066467847,0.034949527,-0.055579245,0.023591427,-0.043232349,0.026456351,-0.08006804,1.251121256,2.93995983,1.27834319,1.014416122,1.5138544459999999,1.651493874,1.1599047009999999,1.052046806,-2.70010411,1.6710117480000002,-1468.6251936480403 -2523,2523,H156W,-0.025378777,0.009689666999999999,-0.005721979,0.014182097,-0.042865849000000004,-0.014523413,-0.070279275,0.019521722,-0.011595542,0.055117669,-0.035738336,0.022825967000000003,-0.034269925,0.01136923,0.016994963999999998,-0.032056797000000005,-0.053674900000000005,1.1920843540000001,2.4699333230000002,-3.8229549730000003,-3.68084642,-3.427587982,-3.5603467330000003,-4.161780327,-4.284213402,-6.545712343,-3.473903061,-1462.6694771191105 -2524,2524,H156V,-0.036787787999999995,-0.028977481,-0.030686662000000003,-0.037564021,-0.079730457,-0.021039885,-0.100679689,0.027104114,-0.020340733,-0.011958553,-0.045996409,0.028093053,-0.08946637699999999,-0.017841799,-0.057286242,-0.05447889,-0.10498202400000001,1.3665213569999999,2.44779904,-1.2476062270000001,-0.922966278,-1.104612732,-1.07015863,-1.4756937940000001,-1.664599701,-4.437423739,-0.600127589,-1458.9490572507493 -2525,2525,H156Y,-0.064005058,0.020429122,0.012173881999999999,-0.027288503,-0.002911655,0.041098586,-0.059093424000000006,-0.068916692,-0.035449785,0.070976361,-0.030118117000000003,0.042229301,-0.017881537,-0.008059077,-0.046517929000000006,0.028469435,-0.034292744,1.125323858,2.573922852,-3.0584385419999998,-2.54501503,-2.665190285,-3.2719638439999996,-3.025360451,-3.784663101,-5.347297279,-2.127439768,-1459.0590033633634 -2526,2526,V157A,0.007986192,0.009309956999999999,-0.021504657000000003,-0.037041243,-0.049961013,-0.045121338,-0.02201055,0.037982932999999997,0.027922016,-0.021914187,0.0405341,-0.063905856,0.020896542,-0.049213235,-0.024869251000000002,-0.07953139099999999,-0.020390633999999998,1.329353049,2.299317259,-3.169581964,-3.6593495560000004,-3.4254684369999997,-2.7850598069999997,-2.948949608,-3.0290824130000003,-4.279568631,-1.4398976019999998,-1449.629293808248 -2527,2527,V157C,0.084954012,0.012562658,0.025972172999999998,0.012285342,-0.134334239,-0.004265398,0.078120435,0.091787589,-0.0028093709999999997,-0.06265530700000001,0.08778062199999999,-0.06438972400000001,0.11633407,-0.038264444,0.062835127,-0.162790796,-0.105877681,1.391379159,2.1955583880000002,-7.321403911,-7.892734428,-7.202978905,-6.863465248,-7.244085747000001,-7.403755226,-7.986200681000001,-5.469944189,-1450.2499114731327 -2528,2528,V157E,-0.10696642199999999,0.017066138,-0.041678455,-0.025078306,-0.058903587,-0.004520905,-0.153480035,-0.060452809,-0.056893665999999996,0.067774528,-0.033642253,-0.023431617999999998,-0.059925292000000005,0.015065903,-0.065222515,-0.035689096000000003,-0.082118078,1.117367883,2.476741575,-3.25021282,-3.876705284,-2.877288437,-3.41701593,-3.3428270419999997,-2.737227409,-4.136290335,-1.422860953,-1451.2147744251415 -2529,2529,V157D,-0.0020443370000000002,0.005075446,-0.00477866,-0.079742038,-0.082892483,-0.09744030099999999,-0.0628855,0.058796827,0.00106587,-0.0039149729999999995,0.014065863999999999,0.00782752,-0.01738484,-0.070744501,-0.088739575,-0.150696235,-0.01508873,1.463569959,2.22689915,-4.612984422,-5.450246155,-4.859641068,-4.161918457,-3.95824292,-4.6348735119999995,-5.801194455,-0.513878806,-1450.2066910397261 -2530,2530,V157G,0.10794594800000001,0.191189492,0.01376128,0.003002917,-0.292355779,-0.011331775,0.074179539,0.14171235599999998,0.027074472999999998,0.180638887,0.20174009699999998,0.038368337999999995,-0.010845778,0.057385578,-0.051379744000000005,-0.212819433,-0.371892125,1.095799386,1.869075274,-6.0220802220000005,-7.648190269,-4.6925456389999995,-5.270106941,-5.8960850979999995,-6.60347316,-5.548830965,-0.548143617,-1447.2083483557217 -2531,2531,V157F,-0.007756688,0.003720795,-0.022351098,-0.055792264,-0.033174397,-0.07926577900000001,-0.019010585,0.0034972090000000003,0.022708491,-0.025023884,0.032465472999999995,-0.07319880599999999,0.028496611,-0.016428786,-0.095155741,-0.113066796,0.046718002,1.4009049219999998,2.277511735,-4.6704772089999995,-4.969606888,-4.352804314,-4.898512177,-4.524869492,-4.606593178,-5.820973962999999,-4.535583336,-1455.5164973866194 -2532,2532,V157I,0.008875801,0.035812307,0.014339178999999999,0.008850037,-0.016144166,-0.087609895,-0.016888417,0.034640018,0.009676286999999999,0.047326115,0.024298497999999998,0.041091196,-0.012412838,0.014698422,0.0030016509999999997,0.018967839,-0.051256170999999996,1.1122792190000002,2.6324447930000003,-1.6409339859999998,-1.62044603,-1.5254786759999999,-1.7513616330000001,-1.825927551,-1.481456039,-2.819401069,-2.073549086,-1457.8542840960436 -2533,2533,V157H,-0.044571050999999993,0.060833498,0.033880164,0.00034067900000000004,-0.028670375,-0.075986231,-0.09326186,0.004119758,-0.069118608,0.048976245,0.07269075,0.055996382000000004,0.011763946,0.047731714,-0.047050355999999995,-0.045777879,-0.01156287,1.19428499,2.477242401,-4.302297868,-4.704184357,-4.766113251,-4.0632901310000005,-3.7877821039999997,-4.190119499,-5.135493435,-1.5600190280000001,-1453.444331806153 -2534,2534,V157K,0.022282207000000002,0.014994963,-0.008282013000000001,0.0008595639999999999,-0.06893156,0.016136523,-0.031403631,0.075968044,-0.031896207999999995,-0.017291521,0.047281446,-0.051811308,0.035247283,-0.0056121980000000005,0.007331325,-0.09863342300000001,-0.039229696,1.343734125,2.293345447,-3.253023756,-3.905307495,-3.620977875,-3.6851141739999997,-3.029333694,-2.0243855440000003,-4.328695129,-1.929641125,-1453.327226315625 -2535,2535,V157M,0.02340169,-0.019685983,-0.019215341,0.011822794,-0.110101585,-0.078687083,0.014002998000000001,0.032800381,0.05095052,-0.05962771,0.020255745,-0.039449345,0.001018663,-0.038077633,0.061723220999999995,-0.118598559,-0.101604611,1.396889719,2.271492265,-3.099042305,-2.393574715,-2.7700798260000004,-3.1501124039999997,-3.352951286,-3.828493294,-3.9438601560000004,-3.458638005,-1453.6413881056942 -2536,2536,V157L,-0.016502679,0.00856212,-0.024722348999999998,-0.027218815,-0.159833685,-0.051930040999999996,-0.030786418,-0.00221894,-0.020383651000000003,-0.023481096,0.040605336,-0.056048905999999996,0.006604208,-0.031286181,-0.023151448999999998,-0.161697204,-0.157970165,1.612664549,2.3511978609999997,-2.975976044,-2.94330793,-3.074684273,-2.514048073,-2.625054993,-3.72278495,-5.01423233,-2.978221397,-1448.8042907407507 -2537,2537,V157N,0.000198755,0.03000856,-0.031966483,-0.004686483,-0.148758043,0.020972032,-0.0021186079999999997,0.002516117,-0.023868458,0.019487978,0.040529142000000004,-0.08558820199999999,0.021655236,-0.009035113,-0.00033785300000000005,-0.133638187,-0.163877899,1.288931804,2.2115706569999998,-4.727192067,-5.578263596,-4.589474457,-5.069303925,-4.866163574,-3.5327547839999998,-6.067978776,-0.8715916309999999,-1454.8008868875913 -2538,2538,V157Q,-0.028725188,0.033604028,0.033820561,-0.061760167000000005,-0.034791114,-0.084827921,-0.101191564,0.04374118900000001,-0.032561979,0.012268268,0.054939787999999996,-0.010704248999999999,0.078345371,-0.032506184,-0.09101415,-0.061165620999999996,-0.008416606,1.4040708259999999,2.462408032,-2.9527749880000003,-3.366416473,-3.414064003,-2.88609211,-2.762900558,-2.334401794,-4.400198822,-1.245940109,-1455.181586945895 -2539,2539,V157P,-0.023004699,0.03979491,-0.8276222990000001,-1.9120909959999999,-2.508478619,-0.015592914,-0.014112959,-0.031896438,-0.024791543,0.015971676,0.063618144,-0.537258239,-1.117986359,-1.731426245,-2.092755747,-2.316537655,-2.700419583,1.74226861,0.84392402,-7.171530978,-8.132885482999999,-6.945380248999999,-6.580752251,-6.756553557999999,-7.442083351,-6.160434565,-4.1539961839999995,-1441.310927062761 -2540,2540,V157S,-0.004358762,0.033163936,-0.001189644,-0.009443115,-0.068319607,-0.06028089,-0.038997988,0.030280465,-0.01391897,0.005455021,0.06087285,-0.019964785,0.017585497,-0.005281905999999999,-0.013604324,-0.047715981,-0.088923233,1.2621329940000001,2.44424151,-3.60658513,-4.741048286,-3.5495954060000003,-3.3129704739999997,-3.2466201860000004,-3.1826912989999996,-4.140282437,-1.38262434,-1451.1926407488063 -2541,2541,V157R,0.011059736,0.04024141,0.019991246,-0.012669237,-0.100719758,0.005986241999999999,-0.013690598,0.03581007,-0.006412719,0.018381351,0.062101468,-0.012765894,0.052748385999999994,-0.028494431,0.003155957,-0.120336125,-0.08110339,1.409320366,2.280302418,-4.568367793,-5.627642571,-4.679623375,-3.990448166,-3.7756510160000003,-4.768473838999999,-5.734794798999999,-1.423671343,-1452.199641938787 -2542,2542,V157T,-0.022025257000000003,0.019373934,0.004638975,-0.011490753000000001,-0.050944736,-0.009981433,-0.050543999000000006,0.006493486,-0.014280938,0.018145144,0.020602723,-0.007243716999999999,0.016521667,-0.012138635,-0.01084287,-0.069706728,-0.032182743,1.3596033180000002,2.454671115,-1.154105035,-1.4847883830000002,-1.0754944990000002,-1.170520035,-1.359177597,-0.6805446620000001,-1.968892619,-0.629145117,-1456.3865489582531 -2543,2543,V157W,0.007498571999999999,0.071943872,0.046693488,-0.014799063999999999,-0.063348543,0.006335748,-0.008847174000000001,0.023844318,-0.02232801,0.052239618,0.091648125,0.016267613,0.077119362,0.013688938000000001,-0.043287066,-0.09457019900000001,-0.032126886,1.346578525,2.32614318,-5.8764666839999995,-6.500454124,-5.568955223,-5.456357124,-5.407332962000001,-6.449233986,-6.824008517,-4.798203921,-1460.1120948172174 -2544,2544,V157Y,-0.026986842999999996,0.089823681,0.071057583,0.019410524,0.0042194,-0.054327478,-0.062310576,0.008336890999999999,0.008647984000000001,0.10194207400000001,0.077705288,0.080452194,0.061662971,0.07784526,-0.039024212999999995,0.017561899,-0.009123099,1.301330514,2.932170999,-4.273006175,-4.2795890960000005,-3.33531147,-5.004244934,-4.744499374,-4.001386002,-4.798036843999999,-3.5350816110000003,-1456.2895309268497 -2545,2545,T158A,-0.028880463,-0.011968048,-0.0169454,-0.121961116,-1.75776431,-0.050037362,-0.030818876000000002,-0.026942049,-0.044752917999999996,-0.016594137,-0.007341958000000001,-0.015432313000000001,-0.018458486,-0.071642508,-0.172279723,-1.706419375,-1.809109245,0.91354021,1.322989124,-6.74590338,-6.753515366,-6.024180199,-6.620997185,-7.572899917999999,-6.757924232000001,-7.615992122000001,-5.09847707,-1454.9866537647322 -2546,2546,T158C,0.014937236000000001,-0.059811937,-0.35263371600000004,-1.979025918,-2.074436607,-0.066666054,0.03415179,-0.004277319,-0.017442138,-0.097693744,-0.021930129,-0.18645555100000002,-0.51881188,-1.461092812,-2.496959023,-2.195292493,-1.95358072,2.521829597,1.552393897,-8.816079497,-9.111968544,-7.680197968,-9.358273827,-8.877467171000001,-9.052489975,-8.306899929,-5.248514957,-1461.4420233848505 -2547,2547,T158E,-0.08650744699999999,-1.175465311,-1.994885235,-2.4617506959999997,-2.826795965,-0.038013063,-0.10460106699999999,-0.068413827,-0.029609500000000004,-0.973438626,-1.3774919959999998,-2.142191176,-1.847579294,-2.101827499,-2.8216738930000003,-2.676326337,-2.9772655930000003,0.339241367,-0.633590368,-10.49318647,-10.61954129,-8.337820236,-10.82387936,-12.14736702,-10.53732446,-9.656081126,-7.636737711,-1458.4329790081829 -2548,2548,T158D,0.095400055,-0.5866281329999999,-2.054794181,-2.158160277,-2.857708937,-0.06140133,0.14687877300000002,0.043921336,-0.027128158,-0.494761846,-0.6784944190000001,-2.402412347,-1.707176014,-2.237109933,-2.079210621,-2.635517512,-3.079900362,0.401892611,-0.486329356,-10.78483629,-10.97438513,-9.745017288,-11.03253608,-11.59516908,-10.57707387,-9.710414099,-7.636737711,-1455.9092406728305 -2549,2549,T158G,-0.028441239,-0.010144088,-0.038873325,-0.957233643,-2.322613955,-0.012227968,-0.011574282,-0.045308195,-0.034284426,-0.020700154,0.00041197900000000003,-0.052958625999999995,-0.024788023,-0.44292479,-1.471542495,-2.04714551,-2.598082399,1.7311426269999999,1.35983682,-5.615739685,-6.421732544,-5.241361717,-5.506715347,-6.070659134,-4.838229683,-6.376746154,-4.621285299,-1455.5301634147763 -2550,2550,T158F,0.061257886,0.013099162,-0.031020341,0.023313035,-1.662542725,0.044757627,0.117896604,0.004619168,-0.014174414,-0.020031826000000003,0.046230149000000005,-0.13126633099999999,0.06922565,-0.045145162999999995,0.091771232,-1.686590791,-1.638494659,0.808514785,1.318118766,-6.339188605,-6.327151306,-5.758313309,-7.2369213939999995,-6.454403725,-5.91915329,-5.575406967999999,-1.814040475,-1467.2998594734818 -2551,2551,T158I,0.09018035199999999,0.042909660999999995,-0.289801071,-2.0700840830000002,-2.619117745,0.063354391,0.132504931,0.047855773,-0.076993383,-0.031875053,0.117694375,-0.24467862899999998,-0.334923513,-1.464727097,-2.675441069,-2.40720272,-2.83103277,1.42695384,0.820807066,-6.728567758,-7.633880249,-4.275447784,-7.002468155,-6.90516394,-7.825878662,-6.8529601179999995,-1.6219367130000002,-1451.9922447041608 -2552,2552,T158H,-0.005887926,-0.129997274,-1.4000168819999999,-2.3767000780000003,-3.153699718,-0.034001792999999995,0.005409353,-0.017185204,-0.039494911,-0.143775044,-0.116219504,-1.418283014,-1.381750749,-2.508253105,-2.24514705,-2.9066606839999998,-3.4007387510000004,1.045653183,0.089653149,-11.97797269,-12.26819915,-10.0723007,-11.69131924,-12.85421696,-13.00382738,-10.50509567,-9.990787985,-1464.3236256288365 -2553,2553,T158K,-0.019445796,-1.420475329,-2.577818355,-2.6811844519999997,-2.6571540959999997,-0.00726131,0.012847468999999999,-0.05173906,-0.103740919,-1.6585575190000001,-1.182393138,-2.2990362909999997,-2.856600418,-2.434763874,-2.92760503,-2.5321414559999997,-2.782166735,-0.083982765,-1.0795121140000001,-10.71000277,-10.39429324,-9.358348595,-10.42260023,-11.86147739,-11.51329439,-9.705296779,-7.636737711,-1460.7404716014862 -2554,2554,T158M,-0.088305607,-0.050163998,-0.371490407,-2.118906559,-2.833436831,-0.045057174000000005,-0.06938122299999999,-0.107229991,-0.068086765,-0.045216517000000005,-0.055111479000000005,-0.22754187399999998,-0.515438939,-1.935366224,-2.302446894,-2.509865062,-3.1570085989999996,1.227098972,0.692747039,-7.404449721000001,-7.994227477999999,-5.952948532000001,-7.277151054,-8.556643692,-7.241277847,-5.79062572,-2.88888606,-1458.129532769788 -2555,2555,T158L,-0.074344656,-0.35571971,-1.565843171,-2.350798219,-2.71824293,-0.011836931,-0.069025053,-0.079664259,-0.032444284,-0.198216444,-0.513222975,-1.45411917,-1.6775671719999998,-2.221869967,-2.4797264709999998,-2.465375585,-2.971110274,1.569433326,0.210169994,-7.034857142999999,-8.723049377,-4.963083763,-7.669684265,-8.545335129,-5.273133178999999,-6.068846075,-3.1788365489999997,-1451.0592433516867 -2556,2556,T158N,0.011774083999999999,-0.191109825,-1.2999960990000001,-2.332028445,-2.847588712,-0.017818102,0.063519486,-0.039971319,-0.02202226,-0.091459631,-0.290760018,-1.148474901,-1.4515172969999999,-2.011201211,-2.6528556780000003,-2.585700049,-3.109477374,2.402240575,0.9828210620000001,-8.914365842,-8.973008232,-7.3534499360000005,-9.233376418999999,-10.54631986,-8.465674759,-9.025374329,-6.703583065,-1455.3849200797267 -2557,2557,T158Q,-0.018011008999999998,-0.41006510700000004,-1.807096801,-2.347026279,-2.561556551,-0.04480964,-0.023189957,-0.012832061,-0.037983725,-0.237807839,-0.582322374,-1.658693942,-1.955499659,-2.220390256,-2.4736623019999997,-2.493859098,-2.6292540030000002,1.146779821,0.041487212,-9.627094266,-9.871858261,-7.307986794,-9.874044067,-11.7535477,-9.328034508,-7.990517695,-4.709698207,-1459.0648735286668 -2558,2558,T158P,-0.047265934,-0.861978129,-1.937056479,-2.371801492,-2.6938364260000003,-0.04161215,-0.03852653,-0.056005337,-0.001364811,-0.7088969079999999,-1.0150593490000002,-1.897852844,-1.976260114,-2.179708461,-2.563894522,-2.550087316,-2.837585535,2.920946179,0.9539960059999999,-10.28377697,-10.21614412,-9.169962257,-10.40614236,-11.48169687,-10.14493927,-9.580546624,-7.606890400000001,-1456.9299480793998 -2559,2559,T158S,0.015033753,0.011266874,-0.020908291000000002,0.004136106,-0.018715579,-0.054606494000000005,0.0031374109999999997,0.026930093999999998,-0.034150704,-0.023250323,0.04578407,-0.001956087,-0.039860495,-0.017824458,0.02609667,-0.038154924,0.000723766,1.441341456,2.634085791,-1.995040804,-1.887696579,-2.629198944,-2.067860832,-2.901416771,-0.489030891,-2.7079398830000003,-1.804535775,-1465.0853974404745 -2560,2560,T158R,0.000780494,-1.5853249759999999,-2.073623984,-2.313490717,-2.8290509839999998,-0.024743489,0.0008451610000000001,0.000715826,-0.118243952,-1.710866618,-1.459783333,-2.147225408,-2.00002256,-2.203771744,-2.42320969,-2.4772405859999997,-3.180861382,-0.23548121800000002,-1.118950065,-11.18140742,-11.19978569,-8.817960402999999,-11.50193285,-12.57058962,-11.81676853,-9.647283605,-7.636737711,-1456.6313729183748 -2561,2561,T158W,-0.001048914,-0.852970888,-1.935432754,-2.456870449,-2.855389113,-0.10954254699999999,0.002327036,-0.004424863,0.013381811,-0.755467532,-0.9504742429999999,-1.8993964980000002,-1.971469009,-1.792086031,-3.1216548669999997,-2.7345616539999997,-2.976216572,3.502028469,1.558197055,-10.85864467,-11.29701408,-9.937060265,-11.85011852,-11.22084641,-9.988184059,-8.610340115,-6.026166153999999,-1470.4149017636664 -2562,2562,T158V,-0.041539086,0.016103403999999998,-0.011243436,-1.232293488,-2.060039083,-0.018751731,-0.016265212,-0.06681296,-0.020814413,0.014433643000000001,0.017773163999999998,-0.009772115999999999,-0.012714756,-0.7067656179999999,-1.7578213569999999,-2.0624212159999997,-2.057656949,1.812751878,1.3843838819999998,-7.682841161,-8.622737572,-5.495376274,-7.336580681,-8.307325401,-8.652185875,-6.931224667,-2.9142473310000003,-1449.0473115583882 -2563,2563,T158Y,-0.057431450999999994,-0.602050125,-1.741436873,-2.505912618,-2.632397259,-0.018531815,-0.074692985,-0.040169916,0.006374023,-0.48246626,-0.7216339890000001,-1.533119497,-1.949754248,-2.51394512,-2.497880115,-2.611322702,-2.653471815,1.7433931480000002,0.237707975,-9.692380902,-9.5484132,-9.006973946,-10.43711009,-8.428070961,-11.04133631,-7.420787025,-4.970833928,-1466.4479219941422 -2564,2564,R159A,-0.041589751,0.018099699,-0.016078471,-0.009174969,-1.81998913,-0.054365795999999994,-0.038926342999999995,-0.044253158,-0.140360605,0.037816101,-0.0016167039999999998,-0.003455391,-0.028701551000000002,0.020323466999999998,-0.038673405,-1.573000696,-2.066977563,0.6060222120000001,1.3126331629999999,-10.06333203,-9.202413597,-9.392203819,-10.83267946,-11.05130489,-9.838058372999999,-8.611336742,-2.3731766469999998,-1440.8830529814586 -2565,2565,R159C,-0.051000738,-0.045488390999999996,-0.044300819000000005,-0.043935397,-1.598124144,-0.072430628,-0.026491672,-0.075509803,-0.075250295,-0.006108904,-0.084867877,0.014719382,-0.103321019,0.028477809,-0.11634860300000001,-1.295489328,-1.90075896,0.8802841090000001,1.3494737769999998,-12.31606937,-11.27984914,-12.00466442,-14.16630684,-12.73819745,-11.39132899,-9.266848145,-5.30288059,-1447.3138080169447 -2566,2566,R159E,0.031932327,-0.015735218,-0.003915812,-0.07301111099999999,-1.826000916,-0.16836612899999998,0.054133043,0.00973161,-0.099250572,0.067088489,-0.098558925,0.025082238,-0.032913861,0.027545461,-0.173567683,-1.585650944,-2.066350888,0.665608126,1.315719665,-8.984364507,-7.497812592000001,-9.552730087,-11.35117878,-8.256558372999999,-8.263542702,-7.296778802,-2.43883982,-1443.9475553994998 -2567,2567,R159D,0.003476165,0.042122712,-0.658410457,-1.8083257030000002,-2.750766539,-0.10758727900000001,0.048747947,-0.041795618,-0.151335045,0.029341792999999998,0.05490363,-0.353493241,-0.963327673,-1.549782175,-2.06686923,-2.44677643,-3.054756647,1.5752823480000002,0.842614192,-10.18176155,-10.512965,-10.97441766,-11.71783959,-9.322845688,-8.380739822,-6.9451951229999995,-2.863109062,-1447.3576876120642 -2568,2568,R159G,-0.002218888,-0.006202985,0.0025941560000000002,-1.029913777,-2.092619471,-0.06335971,0.021176285,-0.02561406,-0.047382213,-0.00142319,-0.010982779,0.006981065,-0.0017927529999999998,-0.535363936,-1.5244636180000002,-1.7654331140000001,-2.419805827,1.808348249,1.4770453940000001,-10.89755506,-7.339528839,-11.07260362,-12.56170866,-12.214936,-11.29899818,-8.068370701000001,-3.500316106,-1437.3289282424375 -2569,2569,R159F,0.146300946,0.054935495,0.140125367,0.070928387,-1.18597189,0.0075222330000000006,0.20050093300000002,0.09210095800000001,-0.569334847,-0.013684553,0.123555543,0.056681224,0.22356950899999997,0.021205283,0.120651491,-1.38607859,-0.9858651890000001,0.7534246059999999,1.3321743129999999,-12.25968075,-12.29506146,-12.09029714,-13.31502723,-11.73356046,-11.86445745,-7.774148651,-4.1004422289999995,-1445.5949714928865 -2570,2570,R159I,-0.172504477,-0.10268725,-0.074923104,-0.075693857,-1.4150535880000001,0.074875835,-0.147759091,-0.197249862,-0.44439611100000004,0.052292674000000004,-0.257667174,0.013632821000000002,-0.163479028,0.10999080300000001,-0.261378516,-1.471250199,-1.3588569769999999,0.47838392399999996,1.311922174,-11.23793614,-11.674665699999998,-11.8942569,-12.93797182,-9.853796165,-9.828990105,-7.114581332,-3.1663546489999996,-1438.766346349381 -2571,2571,R159H,0.038028575,0.020620135,0.011238471000000002,-0.005179846,-0.024222481,0.010654298999999999,0.073903434,0.002153715,-0.031239354,-0.005955111,0.04719538,0.012121103000000001,0.010355839,-0.042974690999999995,0.032614999,-0.021729488999999998,-0.026715472,1.191705043,2.506115455,-5.931717001,-5.950411255,-6.185365845,-7.022521423,-5.826043587000001,-4.674242897,-5.18132903,-2.760801921,-1444.4089335957542 -2572,2572,R159K,-0.009028911,-0.023887062999999997,-0.023743115,-0.078192129,-0.213063427,-0.082231903,-0.042528469000000006,0.024470647,-0.37184544399999997,0.00265531,-0.050429435999999994,0.081190724,-0.128676954,-0.0029283959999999998,-0.153455862,-0.24841660100000001,-0.17771025199999999,1.590887955,2.182387887,-8.513595859,-6.6457785110000005,-9.147201752,-10.24097353,-7.44688295,-9.087142555,-6.739181677,-2.265574989,-1444.820733223576 -2573,2573,R159M,0.013738743999999999,0.027321752,0.005360126,0.02419171,-1.835369183,-0.123062528,0.025238125,0.002239363,-0.211117899,0.029470264,0.025173239,-0.017187485,0.027907736000000002,0.020221604,0.028161816,-1.165568191,-2.505170174,0.59063464,1.330427803,-10.60933649,-9.401110977,-11.01148328,-12.88050896,-9.669185387,-10.08439388,-8.234130867000001,-4.438849478,-1443.1817320818081 -2574,2574,R159L,-0.0338852,-0.039064701,-0.0052510840000000005,-0.069197161,-1.8990577219999998,0.013282291000000002,-0.004527408,-0.063242991,-0.28589517600000003,-0.01133377,-0.066795631,-0.016412201,0.005910033,-0.028147009,-0.11024731199999999,-1.655403626,-2.142711817,0.850632225,1.3232654259999999,-9.01914816,-9.008939041,-9.475481071,-10.54249068,-7.820228462,-8.248601547,-6.9317394320000005,-3.526506195,-1444.5588654605672 -2575,2575,R159N,0.064347058,-0.047621030999999994,-0.048171944,0.038834367,-1.158634112,-0.040648237000000004,0.10260546300000001,0.026088653,-0.205514022,-0.018574885,-0.07666717599999999,0.047651908,-0.143995795,0.040181209,0.037487525,-0.624317755,-1.692950468,0.677908692,1.403005034,-9.233042659,-8.491120781000001,-10.86623704,-10.543688699999999,-8.140628365,-8.123538414,-6.973668223,-2.495390487,-1442.6866910504177 -2576,2576,R159Q,0.033417452,0.058159924,0.010645542,0.06470611700000001,-0.117895174,-0.015205783,0.027813917,0.039020986,-0.06537309,0.063450975,0.052868872000000004,-0.00156082,0.022851903,0.064207447,0.065204786,-0.136088619,-0.099701728,1.398049603,2.2762375230000003,-5.3583767589999995,-3.935880661,-6.341570549,-6.797848366,-4.913378532,-4.803205688,-4.807205271,-2.147814404,-1448.5930357729085 -2577,2577,R159P,-0.006923264,-1.343820663,-1.6551942659999999,-1.8226595230000002,-2.195801354,-0.042590282,0.029434187999999997,-0.043280715,-0.296960323,-1.331036313,-1.356605012,-1.450403254,-1.8599852769999998,-1.585994348,-2.059324697,-1.7820033069999999,-2.6095994,4.390451871000001,2.459729036,-11.83971781,-10.84034904,-11.43172881,-12.65912663,-12.61056439,-11.65682016,-9.183697047,-5.372069978,-1449.0842403885908 -2578,2578,R159S,-0.025436437000000003,0.008900098,0.0069144459999999994,-0.0009096839999999999,-0.47621861200000004,-0.024304113999999998,-0.03473233,-0.016140543,-0.27736646600000003,-0.000932283,0.018732479,0.004165614000000001,0.009663277,0.008515159,-0.010334527,-0.385594965,-0.566842259,0.626323886,1.453160789,-7.431824477,-6.534859572999999,-7.154044098,-9.169239365,-7.3385028310000004,-6.962476517000001,-6.851931594,-2.126348867,-1434.7401630370878 -2579,2579,R159T,-0.027211309,0.00382007,0.02618152,0.022318705,-0.293486986,0.029490659,-0.009337243,-0.045085375,-0.172423615,0.033378944,-0.025738804,0.057184900000000004,-0.004821860999999999,0.042994483,0.0016429270000000002,-0.20256715600000003,-0.384406815,1.244270113,2.034478831,-9.118734329,-7.468052482999999,-8.486753928999999,-11.49363973,-9.421552887,-8.723672615,-7.2112169889999995,-2.496908887,-1434.8324755690992 -2580,2580,R159W,-0.021042252999999997,0.021291951,0.01241816,0.009298701,-1.56451437,-0.008446434000000001,-0.011811265,-0.03027324,-0.142589896,0.066272912,-0.023689011,0.04562425,-0.020787931000000003,0.068526283,-0.049928880999999994,-1.572108371,-1.556920369,0.46587897799999994,1.307066499,-11.35921426,-11.56165385,-11.27827748,-12.56290557,-12.03142344,-9.361810951,-8.951126341,-4.610138605,-1457.241772344103 -2581,2581,R159V,-0.022112762999999997,-0.004521954,-0.004261753,0.032257454,-1.5021838980000002,0.016255024,0.011722264,-0.05594779,-0.01876313,0.030453944,-0.039497851,0.000432145,-0.00895565,0.02930425,0.035210657,-1.27886862,-1.725499176,0.6726552090000001,1.3316622329999999,-9.958154842999999,-9.42711216,-10.2285022,-11.58786279,-9.314030937,-9.233266121,-7.054396529,-1.9378355719999998,-1442.2301500451285 -2582,2582,R159Y,-0.036953786,-0.030407612,-0.018138127,-0.007278884,-1.576523906,-0.081381179,-0.054220714,-0.019686857,-0.428601844,-0.11567409199999999,0.054858869000000005,-0.024434521,-0.011841731999999999,-0.041926303,0.027368536000000002,-1.6291166380000002,-1.523931173,0.7953359729999999,1.318408427,-12.4374916,-13.39978756,-13.73899608,-13.61253504,-11.48891695,-9.947222343,-8.265361996000001,-4.581534543,-1445.2428852608427 -2583,2583,L160A,0.027406827,0.00318338,-0.009497183000000001,-0.007459671,-0.20360832,0.009191616,0.053186612,0.001627041,-0.007138210999999999,0.031725311,-0.025358551,0.019343371,-0.038337736000000004,-0.028661322000000003,0.013741981,-0.18373275,-0.223483889,1.4723182209999999,2.208962197,-9.627284598,-9.557653595,-9.578898613,-9.436677498,-11.97117282,-7.592020462000001,-6.4314914739999995,-2.943898503,-1452.2907130601816 -2584,2584,L160C,-0.016330782,-0.048708549000000004,-0.024557762,-0.056976938,-0.091992954,0.115533916,-0.004382021,-0.028279542999999997,-0.007044381,-0.046933944000000005,-0.050483154,-0.019849968,-0.029265556,-0.08890388800000001,-0.025049987000000003,-0.14081137900000001,-0.043174529,1.538648525,2.323131466,-9.786634557000001,-10.7983765,-8.938656822,-11.45994267,-11.84915794,-5.887038849,-6.668783029,-4.078032847,-1452.4386701858602 -2585,2585,L160E,-0.001251956,-0.054386705,-1.09653147,-1.935660269,-2.544298692,-0.066568312,0.053292472,-0.055796383,-0.029958389,2.3100000000000002e-05,-0.108796509,-0.823026322,-1.370036618,-1.90911358,-1.9622069569999998,-2.140302118,-2.948295266,3.422476863,2.079461125,-12.86631747,-12.43247539,-12.32604844,-14.11301208,-15.0241438,-10.43590766,-8.249225809,-5.79739118,-1449.7734666494653 -2586,2586,L160D,-0.05402176,-0.105071612,-0.8064515640000001,-2.2248481140000003,-2.836727602,-0.06641649599999999,-0.042430262,-0.06561325700000001,-0.020231871000000002,-0.136840518,-0.073302706,-0.317309701,-1.295593427,-1.500306973,-2.949389255,-2.539609985,-3.1338452180000003,1.556864333,0.8495376809999999,-14.66176838,-15.20248042,-13.801995000000002,-15.44929353,-16.78318984,-12.07188309,-9.524716155,-7.845160433999999,-1452.015819025226 -2587,2587,L160G,-0.03006907,-0.015225293,0.00706394,-1.256283636,-2.25622662,-0.04094174,0.0028218490000000004,-0.062959988,-0.066827684,-0.003770238,-0.026680347000000004,0.029104475,-0.014976596000000002,-0.7886643,-1.723902971,-2.037492964,-2.474960276,1.9697112209999998,1.4478640719999998,-14.21309673,-14.50839871,-13.43961076,-15.26296598,-16.30214053,-11.55236767,-9.330793128,-7.35093058,-1448.172598676756 -2588,2588,L160F,0.00864185,-0.016097075,0.012485343000000001,-0.016523232,-0.571760779,0.030664561,0.043449811,-0.026166112000000002,0.025545592000000002,-0.03204472,-0.00014943,0.003176987,0.021793697999999997,-0.075611033,0.042564569000000003,-0.5420424420000001,-0.601479115,1.411205759,1.7556639859999998,-7.784257086,-8.054141212000001,-6.199143089,-10.04012254,-8.976743782,-5.651134804,-5.828534096,-2.346543718,-1453.2405572244897 -2589,2589,L160I,-0.022238085,-0.024254286,0.028413255,-0.02777693,-0.040497089,0.135072009,-0.018657061000000003,-0.025819107999999997,-0.039166391,-0.015334958000000001,-0.033173614,0.066904283,-0.010077774,0.018206967,-0.073760826,0.026237833999999998,-0.10723201199999999,1.14065731,2.699438039,-5.3139079360000006,-4.470258972,-5.533962959,-6.226030708,-6.798153778,-3.5411332630000003,-5.057680982,-0.982836658,-1444.1359739499167 -2590,2590,L160H,0.049192075999999994,0.062327627999999996,0.055868585,-0.029899812999999997,-1.822190357,0.020167281000000002,0.098444351,-6.02e-05,0.020251261,0.06938911,0.055266145999999995,0.024003315,0.087733855,-0.09099687699999999,0.031197251000000002,-1.4128464790000002,-2.231534235,0.7664278859999999,1.33038868,-12.2227672,-12.62071987,-10.04760716,-14.09740617,-15.20445188,-9.143650925,-6.662650729,-4.962002266,-1453.9803990293294 -2591,2591,L160K,-0.031891398,-0.16359192,-1.9684773359999999,-2.190818654,-2.626606882,0.046964657,0.00126631,-0.065049105,-0.064807977,-0.077876517,-0.249307323,-2.04328294,-1.8936717319999998,-2.226280212,-2.155357095,-2.311340714,-2.94187305,0.48810381700000005,-0.169310472,-13.58613826,-14.43279289,-12.58210751,-14.52227884,-14.94833145,-11.44518063,-9.204322665,-7.241744587,-1450.6837139055133 -2592,2592,L160M,0.053924209,0.039047466,0.033406332000000004,-0.00713344,-0.16312733699999998,0.058739464000000005,0.098752245,0.009096173,-0.013715702,0.019083992,0.05901094,0.00902616,0.057786502999999996,-0.027520061000000002,0.013253181999999999,-0.16942084,-0.156833834,1.1081098809999999,1.9175844930000001,-5.492166605,-5.508792099,-5.766561501,-6.557824912999999,-5.000112801,-4.62754171,-5.129390433,-2.383283309,-1452.342797223013 -2593,2593,L160N,-0.078962771,-0.10065803400000001,-0.026715061000000002,-0.099119234,-1.9060736040000001,0.107774664,-0.03374028,-0.12418526199999999,-0.068073365,-0.133006247,-0.06830982,-0.091766236,0.038336114,-0.132450675,-0.065787793,-1.572898835,-2.239248372,1.151208795,1.359523324,-11.29894044,-11.83654588,-9.9533283,-13.32575392,-13.22144315,-8.157630928,-7.066454711,-5.323084344,-1452.9379166979343 -2594,2594,L160Q,0.08811052300000001,-0.005413103000000001,0.008325991999999999,0.045480140999999995,-1.9256386580000002,-0.05662399,0.139200348,0.037020698,-0.050846962999999995,-0.005092839,-0.005733367,-0.050849930999999994,0.06750191400000001,0.008651014,0.082309267,-1.777545554,-2.073731762,0.6182098570000001,1.305969224,-9.856484186,-10.73331866,-9.268839737,-10.78133125,-10.66775456,-7.83117672,-6.830532487,-4.645871965,-1451.5242276629433 -2595,2595,L160P,-0.003801273,-0.015809232,0.015403106000000001,-0.9296758620000001,-1.980249427,-0.04100322,0.031670754,-0.039273299,-0.037517363,-0.013398549,-0.018219914,-0.00045552300000000005,0.031261734,-0.447670996,-1.411680728,-2.1668727569999997,-1.793626096,1.660382438,1.335879095,-12.25372011,-13.57795429,-12.48347221,-14.93040726,-12.17743493,-8.099331871,-6.478473452,-2.63249621,-1450.9313588077202 -2596,2596,L160S,0.001387136,-2.7899999999999997e-05,-0.023298053,-0.013600556000000001,-0.219697753,0.027127415,0.020343581,-0.01756931,-0.012158391999999999,0.011983863999999999,-0.012039713,-0.017045398,-0.029550708,-0.045515802,0.01831469,-0.165666882,-0.273728623,1.417606837,2.164073798,-7.6387338410000005,-6.493185112000001,-7.946908791,-9.210125999,-9.934336006,-4.6091132969999995,-4.423453778,-3.0177352930000003,-1452.0280522322282 -2597,2597,L160R,-0.03361549,-0.837751162,-1.882843034,-2.1710204109999998,-3.3928570239999996,0.0070047009999999995,0.020475862,-0.087706842,-0.041744426,-0.67056515,-1.0049371740000002,-1.909453525,-1.8562325430000002,-2.0924507969999997,-2.249590025,-2.84651808,-3.939195967,2.951804427,0.990794217,-12.70903158,-13.25827647,-11.79646166,-13.49984899,-14.61621581,-10.37435497,-7.581360097999999,-4.490438877,-1441.8017230816185 -2598,2598,L160T,0.001835825,0.02036359,0.039080058,0.031371965,-0.27647592,0.04679359599999999,0.002682849,0.000988801,-0.110502912,0.034800015,0.005927164,0.08209404599999999,-0.00393393,0.036596627,0.026147302999999997,-0.217470238,-0.335481601,1.4159215669999998,2.135894609,-10.1569795,-9.967608986,-10.78371256,-10.98184974,-11.58865354,-7.463072692999999,-6.444531636000001,-4.104247322,-1448.2760248705745 -2599,2599,L160W,-0.043526455,-0.131249371,-1.696969041,-2.312522247,-3.154767154,0.023982412999999998,0.008723746,-0.095776655,-0.068691578,-0.038339498,-0.22415924399999998,-1.795340474,-1.5985976080000002,-2.330520264,-2.29452423,-2.716610761,-3.592923546,0.526994339,-0.044521729,-13.09213344,-13.98359287,-11.61586096,-14.70507079,-14.26106961,-10.89507295,-8.63791186,-6.545641297,-1457.0590738849714 -2600,2600,L160V,-0.018478405,-0.015216865,-0.025935664,-0.042705096,-0.052868258,0.14753859800000002,-0.012886700000000003,-0.024070109,-0.017423207,-0.003132138,-0.027301592000000003,-0.029038582,-0.022832745,-0.07003190200000001,-0.015378289,-0.044533582,-0.061202933,1.306301299,2.40719048,-6.454776016,-6.050416077,-5.953768822000001,-7.709530937,-8.619635642999999,-3.940528603,-3.73514128,-0.82363787,-1450.217965272721 -2601,2601,L160Y,-0.056448264000000005,0.00716131,-0.9886035590000001,-2.018092101,-2.876429349,-0.029792144,0.008754434,-0.12165096199999999,-0.013920123999999999,0.044579035999999995,-0.030256417,-0.7041842840000001,-1.273022834,-2.142454061,-1.89373014,-2.528544559,-3.2243141389999996,1.7458827319999999,0.6976246709999999,-12.39292286,-13.38622007,-10.50140802,-13.9722675,-14.02762264,-10.07709606,-7.313237053,-4.647974201,-1452.8002481660806 -2602,2602,D161A,-0.10834899,-0.061708135,-0.054588507,-0.047746776,-1.7242390669999998,0.075072134,-0.085812963,-0.130885017,-0.007822676,-0.033517133,-0.08989913699999999,-0.043470657999999995,-0.065706355,-0.031212797,-0.06428075400000001,-1.589715114,-1.858763019,0.629716331,1.312791792,-9.398640111,-8.97341468,-9.096185973999999,-10.9373978,-8.487806137,-9.498395966,-7.543120387,-1.995660061,-1436.22332156403 -2603,2603,D161C,-0.09829915300000001,-0.02249329,-0.015560947,-0.131804351,-1.714345305,0.08841106800000001,-0.066839766,-0.12975854,0.004802231,0.010908957,-0.055895535999999996,0.033313033,-0.06443492599999999,-0.063589881,-0.20001882,-1.788621834,-1.640068776,0.8861056270000001,1.316093513,-15.12244929,-16.733535999999997,-15.05192912,-15.76705503,-13.16540733,-14.89431895,-9.889363994,-6.146411962,-1449.075562747661 -2604,2604,D161E,-0.062340605,-0.032277667,-0.064318609,-0.016074263999999998,-0.9411997740000001,0.08552439,-0.02223435,-0.10244686,-0.032761795,-0.049393072999999996,-0.01516226,-0.06266999,-0.065967228,-0.012927001,-0.019221527,-0.9949746979999999,-0.88742485,0.646441054,1.3506049409999998,-7.835697556,-9.157033813,-7.098443764,-7.385292037999999,-6.507110626,-9.030607536,-5.515764832,-2.081012008,-1446.2429459183477 -2605,2605,D161G,-0.070989359,-0.036877915,-0.072913283,-1.836174552,-3.112543508,0.118624613,-0.046324672000000004,-0.09565404599999999,-0.014571361000000001,-0.038442877,-0.035312953,-0.051654605,-0.09417196,-1.589016789,-2.083332314,-2.637730008,-3.587357007,0.762656806,0.701592952,-12.32699115,-10.29972762,-11.62486637,-14.48310667,-10.74828979,-14.47896528,-7.890100144,-2.33064941,-1437.644341881387 -2606,2606,D161F,-0.105109097,-0.06257547200000001,-0.070186455,-1.84345872,-2.7461425139999998,0.10926626699999999,-0.048536830999999996,-0.161681363,-0.045483401,-0.050100374,-0.075050569,-0.106545536,-0.033827373,-1.604248747,-2.082668693,-2.453092861,-3.0391921660000003,1.0027090909999998,0.7197993340000001,-16.42005556,-15.78095635,-17.21906222,-16.02111028,-16.17914095,-16.90000802,-9.307677933999999,-4.814406953,-1446.502554402221 -2607,2607,D161I,-0.048420987,-0.039690502,-0.032382938,-0.995981875,-2.7548884769999997,0.063070393,-0.020757769,-0.076084205,-0.052951442,-0.09787863599999999,0.018497632,-0.007170228000000001,-0.057595647,-0.564821618,-1.427142132,-2.63709087,-2.872686083,0.927171874,0.893497188,-13.79137438,-14.17358899,-13.99844852,-13.18120758,-13.3242634,-14.27936342,-8.397130688999999,-3.4725668489999997,-1437.8143122280017 -2608,2608,D161H,-0.095353583,-0.065950842,-0.058164247,-0.024234272999999997,-1.928225329,0.053954759000000005,-0.058767390999999995,-0.131939774,0.062654592,-0.060229229,-0.071672455,-0.063000175,-0.053328318,0.021259421,-0.069727966,-1.600282847,-2.25616781,0.69345813,1.316599517,-12.87713665,-13.967882000000001,-11.933867800000002,-13.71345004,-10.81879561,-13.95168781,-8.339767128,-3.318978514,-1441.4721747874282 -2609,2609,D161K,-0.12650453,-0.07254445400000001,-0.316735638,-2.316746905,-2.460173728,0.09502537300000001,-0.09578541900000001,-0.15722364,-0.082168586,-0.064719543,-0.080369364,-0.178931024,-0.454540251,-1.5971068000000002,-3.036387009,-2.550686264,-2.369661191,1.1887945309999999,0.743321751,-13.23109526,-14.49564706,-13.08944471,-14.46954542,-10.31582945,-13.78500966,-8.284320425,-2.3216394819999997,-1439.5260343332775 -2610,2610,D161M,-0.156952801,-0.118727154,-0.09845992,-0.171500113,-1.9261155030000001,0.087543348,-0.11565978199999999,-0.19824582,0.044812985,-0.053757877999999995,-0.18369643,-0.097229581,-0.099690258,-0.10402619,-0.238974035,-1.889201224,-1.9630297819999998,0.983920804,1.3155101740000001,-15.51436799,-15.83515818,-15.97575707,-15.192527499999999,-13.30160258,-17.2667946,-9.182369938999999,-5.114383022,-1439.36630511377 -2611,2611,D161L,-0.089750285,-0.06971346,-0.224141808,-1.8933294440000001,-3.35120605,0.051837941,-0.089296739,-0.09020383,0.002524325,-0.021009012999999997,-0.11841790699999999,-0.149845863,-0.29843775300000003,-1.666042222,-2.120616666,-3.041695375,-3.660716724,1.026334181,0.714551904,-13.68521433,-14.11459354,-14.47441222,-13.95612801,-12.00477789,-13.87616,-8.451608366,-2.516541712,-1429.4173984462395 -2612,2612,D161N,-0.07002509,-0.00172883,-0.080452993,0.001966741,-0.6219629170000001,0.11120781199999999,-0.008209159,-0.13184102,0.042131012,-0.015790632,0.012332972,-0.019798225,-0.141107761,-0.033083609,0.037017091,-0.662057539,-0.581868295,0.896732779,1.449667508,-8.572680447,-9.59049408,-7.637481316000001,-9.495830977999999,-8.082341492000001,-8.057254372000001,-7.197342792000001,-1.746783276,-1441.096313314978 -2613,2613,D161Q,-0.070759951,-0.056316367,-0.050416548,-0.170371534,-1.8701802109999999,0.048214158,-0.026522888999999997,-0.114997012,0.04172875,-0.04031377,-0.072318964,-0.064401974,-0.036431121000000004,-0.09467968,-0.246063388,-1.7014716580000002,-2.038888763,1.363000051,1.379699534,-12.83102828,-15.19735185,-13.13547095,-12.9504473,-11.39873111,-11.4731402,-6.898414785,-2.1099339440000002,-1437.8840012000874 -2614,2614,D161P,-0.07721476,-1.5536223880000002,-2.194788319,-2.230308746,-3.45690128,0.052037239000000006,-0.035432784,-0.118996735,-0.022434102999999997,-1.584715869,-1.522528906,-2.061816677,-2.327759961,-1.979390102,-2.481227389,-3.0878715260000003,-3.8259310330000003,-0.131189854,-1.005753369,-14.87375725,-15.91686683,-14.39036547,-15.16599724,-14.22465984,-14.67089685,-9.654606453,-5.400574416,-1446.8945025904104 -2615,2615,D161S,-0.083540559,-0.057183397999999996,-0.061549994000000004,-0.036778073,-1.313168235,0.130557325,-0.052596211,-0.114484907,-0.034780964,-0.059310894,-0.055055901,-0.049420908,-0.07367907900000001,-0.035981664,-0.037574481,-1.081416951,-1.5449195180000002,0.819974193,1.363870968,-8.806065321,-11.44112521,-7.571183075,-10.11536168,-7.030923386,-7.871733261,-5.605814856,-2.553518119,-1434.120477131568 -2616,2616,D161R,-0.08601113099999999,-0.061761507,-0.705353715,-2.155316755,-2.503933896,0.081029585,-0.057967637999999995,-0.11405462400000001,-0.04435846,-0.052330189000000006,-0.071192825,-0.499644766,-0.9110626629999999,-1.741197385,-2.569436125,-2.5289047559999998,-2.478963035,1.769566793,0.8441862929999999,-12.72638799,-14.34664201,-11.84157831,-13.79447385,-10.46859388,-13.18065192,-7.816632365,-1.5564309109999999,-1436.680752553977 -2617,2617,D161T,-0.08186665,-0.037084608,-0.014758338000000001,-0.034511641,-1.5850553090000001,0.10174064,-0.04860552,-0.115127779,0.005038923,-0.012081682,-0.062087533,0.010669672,-0.040186348,-0.018839507,-0.050183774,-1.5387256930000002,-1.631384925,0.872682338,1.329733117,-10.18597303,-11.43014977,-11.13449303,-9.781840851,-8.862585098,-9.720796387,-6.79781238,-2.851261144,-1435.0516741690226 -2618,2618,D161W,-0.019340628999999998,-0.064226418,-0.49690956700000005,-1.822103169,-2.7815416,0.012014423,0.032899655,-0.071580912,-0.027362966000000002,-0.12480377599999999,-0.003649059,-0.333400295,-0.660418839,-1.8307573169999998,-1.813449021,-2.939238741,-2.623844458,1.5104211630000002,0.756367805,-17.14101957,-17.49109698,-16.38699695,-17.52819489,-16.49462246,-17.80418659,-11.04656685,-7.264617223999999,-1453.0278996853158 -2619,2619,D161V,-0.12973411699999998,-0.054072317,-0.049243682000000004,-0.051189816,-1.579928924,0.060259904,-0.105485557,-0.15398267699999998,-0.018214266,-0.040467631000000004,-0.067677002,-0.03067208,-0.067815284,-0.017584113000000002,-0.084795519,-1.5729069119999999,-1.586950936,0.71045965,1.319131681,-10.94645488,-10.58341835,-11.06602533,-10.48153832,-10.65123735,-11.95005505,-6.788903743,-2.127282258,-1435.229199737776 -2620,2620,D161Y,-0.05521422,-0.078894651,-0.039304037,-0.9667892309999999,-2.4218407,0.037602272,-0.06381173,-0.04661671,-0.006073731999999999,-0.14061684300000002,-0.017172458999999998,-0.068245314,-0.01036276,-0.575644274,-1.3579341880000002,-1.9271637469999998,-2.916517653,1.850426471,1.448434552,-16.31672933,-16.953608300000003,-17.55546302,-15.32879086,-15.00440263,-16.74138184,-8.463720157000001,-3.436432182,-1449.0707329139113 -2621,2621,R162A,0.013039334,0.013666853999999999,-0.006380363000000001,-0.003183783,-2.052036726,0.7106767979999999,0.018282793000000002,0.007795874,0.029035292,0.00876204,0.018571667,-0.016076111,0.0033153859999999996,-0.006572555999999999,0.000204991,-1.874608491,-2.229464961,0.712795762,1.303444692,-13.40647427,-12.78526608,-13.526741399999999,-15.22016901,-12.69214344,-12.80805142,-7.007269452999999,-2.67247687,-1446.0202828263864 -2622,2622,R162C,-0.070157827,-0.030887902000000002,-0.004550383,-0.008773342,-1.942558976,0.294017175,-0.071852187,-0.068463467,0.037713558,0.030368741,-0.09214454400000001,0.043769992,-0.052870758,0.043641646,-0.06118833,-1.6810141319999998,-2.204103819,0.5582411860000001,1.305932596,-16.71286543,-16.2110555,-16.72165221,-17.46296417,-17.83572593,-15.33292934,-9.714961215,-6.479640252,-1459.065306416247 -2623,2623,R162E,-0.026155304,-0.027690471,0.018052636,-0.6823396190000001,-2.229220485,0.325070612,0.004625586,-0.056936192999999996,0.004001623,-0.031398702,-0.02398224,0.030851748999999998,0.005253521999999999,-0.38070634600000003,-0.983972892,-2.153409611,-2.305031359,1.436542339,1.319962324,-14.47413447,-16.18828601,-14.014827800000003,-15.10484735,-13.26012266,-13.8025885,-8.150268899,-3.7058631380000002,-1447.0634290571325 -2624,2624,R162D,-0.032867459,-0.049416702,-0.030315453,-0.070850244,-1.797269994,0.9484361240000001,-0.012927126,-0.05280779099999999,0.02339357,-0.021328693,-0.07750471,-0.010777568000000001,-0.049853338,-0.068493068,-0.07320741900000001,-1.249650367,-2.344889621,0.8921156020000001,1.354440736,-13.29316224,-14.91927184,-12.23097237,-13.21223911,-12.85721874,-13.24610914,-6.1916967960000004,-3.373588769,-1441.4275635685772 -2625,2625,R162G,0.017657807,0.012760522,-0.0034966290000000002,-0.013391633,-1.4602986230000001,0.8099812540000001,0.033011083999999996,0.002304529,-0.000111523,0.007741455,0.017779588,-0.013193773999999998,0.006200516999999999,-0.03013575,0.003352485,-1.238914758,-1.6816824869999998,0.693145977,1.335882679,-15.05448282,-14.13933615,-16.15623193,-15.313985500000001,-16.14182278,-13.52103777,-7.5445291160000005,-3.3465632710000004,-1442.0428603026085 -2626,2626,R162F,-0.010716356000000002,0.005011374,-0.164267481,-2.072544665,-2.76348965,0.08646784199999999,0.058080383,-0.079513094,0.042680999000000004,-0.045508541,0.055531288,-0.104509658,-0.22402530399999998,-1.7072739609999998,-2.4378153680000003,-2.3493153159999998,-3.177663983,0.863764761,0.696101757,-17.78978081,-13.83370365,-17.5888504,-17.4662517,-21.53635898,-18.52373933,-8.652674937999999,-4.4470258419999995,-1458.0712066935375 -2627,2627,R162I,-0.036139332999999996,-0.300358296,-2.300576238,-2.2058670780000003,-2.7752930389999997,0.027927163999999997,-0.05733712,-0.014941545,0.086046495,-0.22934022899999998,-0.371376362,-2.279950755,-2.32120172,-2.422461728,-1.989272428,-2.520435039,-3.030151038,0.185996238,-0.419919745,-16.76736429,-15.49182351,-17.73335866,-17.74301726,-16.07133646,-16.79728556,-8.60904314,-4.458766602,-1451.2757044248283 -2628,2628,R162H,0.042839562000000005,0.022684594,0.02638014,-0.016996149,-0.45436417799999995,1.064041417,0.056986913,0.02869221,-0.061643496,0.034096613,0.011272573999999999,-0.005561959,0.058322238,-0.03060076,-0.003391537,-0.413989149,-0.494739207,1.146801791,1.6836855480000001,-8.012232256,-7.638493156,-7.145290695,-8.13841629,-10.35576485,-6.783196289,-6.692561968,-2.320008398,-1453.0927062509581 -2629,2629,R162K,-0.022047389,0.027426871000000002,-0.022070713,-0.018237895,-1.553189419,0.11410754199999999,-0.014212108999999999,-0.029882667999999998,-0.014294336000000001,0.024698839,0.030154902,0.004345422,-0.048486848,-0.025191607,-0.011284183,-1.530919909,-1.5754589280000002,0.605586321,1.313882773,-12.75921038,-13.62157138,-14.00103527,-12.04714088,-12.87576459,-11.25053979,-8.516844276,-4.278501193,-1440.4389315000735 -2630,2630,R162M,0.055510548,0.034168218,0.026430682,-0.675194757,-2.409700729,0.193809325,0.043258549,0.067762547,-0.02366194,0.00485589,0.063480546,-0.050773288,0.103634651,-0.518582831,-0.8318066829999999,-2.07895414,-2.740447318,1.672948852,1.359658812,-16.0001423,-13.50776031,-17.27514378,-17.16194892,-16.62809741,-15.42776106,-8.148495814,-5.105593839,-1452.2713237330317 -2631,2631,R162L,-0.016498782,-0.0027111809999999996,-0.029340266,-1.467066735,-2.600935808,0.11001835300000001,0.004269526,-0.037267088999999996,0.026042311000000002,0.003388197,-0.008810559,-0.057826632,-0.000853899,-1.2147468000000001,-1.71938667,-2.027678221,-3.1741933939999996,2.457822576,1.645030835,-15.37390706,-13.81648914,-16.53858141,-16.99187341,-14.84177122,-14.68082011,-8.198210749,-5.142809617,-1449.3748209606856 -2632,2632,R162N,0.07267294099999999,0.08390529099999999,0.03837183,0.016621897,-0.318084574,1.1137175,0.037385052,0.10796083,0.044287161,0.076755006,0.091055576,0.059341982,0.017401677,0.014248671999999999,0.018995121,-0.243876697,-0.39229245100000004,1.0163317490000001,1.7610112969999998,-13.97357111,-14.85935603,-13.96016421,-13.4612851,-15.45265293,-12.13439729,-7.7140292189999995,-2.21911816,-1441.6389872482978 -2633,2633,R162Q,0.048484828,0.056271311,0.066502918,0.000373536,-0.955581138,0.523068075,0.046162983,0.050806672000000004,-0.026851623999999998,0.030533277999999997,0.082009343,0.071573725,0.06143211,0.012528072,-0.011781001000000001,-0.935905007,-0.9752572690000001,0.643579035,1.354795011,-10.4977702,-10.75079803,-11.21688216,-10.59140076,-10.89104184,-9.038728203,-7.557819222999999,-3.804060528,-1441.5463034030981 -2634,2634,R162P,-0.028398487000000004,-1.4553847119999999,-1.8272121,-1.9387009030000002,-2.4326896280000003,0.090456613,0.017893353,-0.074690327,-0.041242007000000004,-1.531898699,-1.378870724,-1.847033163,-1.807391037,-1.767695386,-2.109706419,-2.564638701,-2.300740554,-0.071866542,-0.97614785,-15.42498967,-16.76628132,-15.59979405,-16.29042326,-12.97398383,-15.49446588,-8.319902109,-3.7203928439999996,-1451.6590531705879 -2635,2635,R162S,-0.000719945,0.013098363,-0.010862563,-0.027030982000000002,-0.46063335899999996,1.129394537,0.000226049,-0.001665939,-0.004210231,0.027935047,-0.0017383210000000001,-0.013147242,-0.008577884000000001,-0.016714365,-0.037347597999999996,-0.38124478799999995,-0.54002193,1.5632782090000001,1.9839067259999998,-13.91110369,-14.34488907,-13.543749400000001,-15.36910068,-13.64308521,-12.65469411,-6.901898123,-2.658960166,-1446.2475078352727 -2636,2636,R162T,-0.052615163,-0.031957021,-0.021453833999999998,-0.031577131,-1.077646983,0.090227991,-0.075330358,-0.029899968,0.005899958,0.03560436,-0.09951840099999999,0.001390903,-0.04429857,0.005121373,-0.068275634,-0.9240022640000001,-1.231291701,0.761670471,1.37192277,-14.19588387,-14.10910554,-13.94850131,-15.59345864,-13.69940262,-13.62895126,-7.791255168999999,-3.157326825,-1448.2101471680216 -2637,2637,R162W,-0.009361966999999999,-0.017632794,-1.308938288,-1.876576085,-3.042912059,0.037447685,0.033261847000000004,-0.051985780999999995,-0.008032719,-0.023586776,-0.011678812,-1.3501507019999999,-1.2677258740000001,-1.969782929,-1.783369241,-2.766726245,-3.319097873,2.651085433,1.138548254,-16.41846195,-16.56449343,-15.56493394,-15.93522244,-19.720653600000002,-14.30700634,-9.487746595,-6.084533048,-1458.6482132817619 -2638,2638,R162V,-0.032957522999999996,0.001723938,-1.201424467,-2.102820185,-3.188958023,0.061281703,-0.008911453,-0.057003592,0.013970781000000002,-0.009716663,0.013164539,-1.12769904,-1.275149893,-1.9581846330000001,-2.247455736,-2.5613079219999997,-3.816608123,2.366014195,0.9963043340000001,-14.71488306,-14.16886832,-16.37949016,-15.90224812,-12.93665727,-14.18715143,-7.610790048999999,-3.7767698189999996,-1448.649427018594 -2639,2639,R162Y,-0.054955,-0.017161983999999998,-0.627198429,-2.4432241969999997,-2.86213516,0.099495989,-0.036273625,-0.073636375,0.043129197,0.001927318,-0.036251285,-0.376340966,-0.8780558909999999,-2.162304615,-2.724143779,-2.5613079219999997,-3.162962398,1.3687651369999998,0.65209001,-16.37081881,-14.57087296,-17.42459633,-15.58610139,-20.5867116,-13.68581178,-8.289931244,-3.983666061,-1455.6957306521945 -2640,2640,W163A,-0.022004943,-0.004331649,-0.03407479,-0.045689653,-0.356231928,-0.043333530999999995,-0.020800868,-0.023209017000000002,0.038732735,-0.021012759,0.012349461,-0.012380216000000001,-0.055769364,-0.056812866,-0.034566439,-0.31722648,-0.39523737600000003,1.52873063,2.0536563919999997,-5.2469057569999995,-6.412155113,-3.9188149639999996,-5.111279091,-5.065495285,-5.726784332,-5.203526917,-2.529995059,-1435.0428115054965 -2641,2641,W163C,-0.01488316,-0.020287351000000002,-0.021445093999999998,-0.024422869,-0.266007873,-0.03436324,-0.009480909000000001,-0.020285411,0.044559034000000004,-0.061874056,0.021299354,0.008430591,-0.051320779000000004,-0.05777657,0.008930832,-0.23968962100000002,-0.29232612399999996,1.275254113,1.9306252169999998,-7.3034675810000005,-8.598191864,-6.12808728,-6.065895821,-7.846106689,-7.879056252000001,-6.819717847000001,-4.539242748,-1448.808189023286 -2642,2642,W163E,-0.009820251,-0.012109613,-0.008143561,-0.001248281,-0.325154719,-0.011510043999999999,-0.014450605,-0.005189895999999999,0.039222532000000004,0.002419241,-0.026638467000000002,-0.029592444,0.013305322,-0.030908188,0.028411627000000002,-0.26668178800000003,-0.38362765,1.305234445,1.928627581,-5.828521883,-6.783417137000001,-5.334286186,-5.829899772999999,-5.680940575,-5.5140657420000005,-6.3835177839999995,-2.409447493,-1440.7590308459476 -2643,2643,W163D,0.014823731000000001,0.00625269,0.0192872,-0.01604435,-0.6581217979999999,0.078159003,0.032444022999999995,-0.002796561,0.055799854,0.007437893,0.0050674859999999995,0.002468905,0.036105494,-0.013324188,-0.018764511,-0.5049814779999999,-0.8112621179999999,0.86310733,1.487320613,-4.966223427,-6.274083191,-2.7418322139999995,-4.654009727,-6.670378922,-4.49081308,-5.696116073,-0.891508741,-1438.6537199844606 -2644,2644,W163G,-0.0032956659999999996,-0.007736018000000001,0.0087194,-0.011963573,-0.720388025,0.000903972,-0.006785942,0.000194611,0.019992153999999998,-0.023939266,0.008467231,0.010092004,0.007346796,-0.027694276,0.00376713,-0.5815482129999999,-0.859227837,0.993326375,1.516977071,-5.753455768999999,-7.0661117860000004,-4.451125275,-5.6176070629999995,-5.544435837000001,-6.087998886,-5.6725333860000005,-0.674048236,-1433.7197084957734 -2645,2645,W163F,-0.02609923,-0.049511665,-0.043193453,-0.005615639,-0.20442420000000003,-0.044948040999999994,-0.044180152,-0.008018306999999999,0.012592403,-0.069898301,-0.029125027999999997,-0.056401127,-0.029985779,-0.050391677999999995,0.039160401,-0.161255924,-0.247592476,1.33500888,2.092666864,-3.832996361,-5.08917205,-2.953329224,-3.087899834,-3.566759537,-4.467821159,-3.507711675,-1.6923281980000002,-1458.4142949855886 -2646,2646,W163I,0.05590327900000001,0.031102247000000003,0.026509827000000003,-0.018841289,-0.058474829000000006,-0.018283128,0.059773815,0.052032742,0.0037742509999999997,-0.013445883,0.075650377,-0.007776873,0.060796526,-0.06694982599999999,0.029267248,-0.13439632,0.017446661999999998,1.4942264840000001,2.3188995169999997,-3.313435425,-4.644261932,-1.841537735,-2.138367195,-4.462929077,-3.480081184,-3.5614123189999995,-0.858343768,-1454.417654347606 -2647,2647,W163H,0.043102825,0.015131977,-0.021810552999999996,-0.003039665,-0.34393850000000004,-0.039147404,0.070472466,0.015733183,0.034037449,0.029690022000000003,0.000573932,-0.07903375,0.035412645,-0.028831303,0.022751973999999998,-0.340479149,-0.34739785,1.478403149,1.961890967,-4.071987851,-5.530912796,-3.886641434,-3.922721878,-3.6058634639999996,-3.413799683,-4.352410154,-2.792137276,-1439.3311604531482 -2648,2648,W163K,0.0036640920000000003,-0.025659179,-0.006395678,-0.028906711,-0.28073449300000003,-0.03393756,0.015744025,-0.008415841,0.020523053,-0.024449989,-0.026868367999999997,-0.023958208999999998,0.011166853000000001,-0.075901186,0.018087765,-0.25048784,-0.310981145,1.666082389,2.228923006,-3.718199545,-5.158211548,-2.37640081,-3.374036812,-4.417221596,-3.2651269610000004,-4.45301294,-0.047543185999999994,-1436.315429248847 -2649,2649,W163M,-0.027461381,0.014279646000000002,0.015744117,0.028577104,-0.069283073,-0.049284425,-0.040138928,-0.014783833,0.02579427,0.045938560999999996,-0.017379269,0.022970251,0.008517983,0.03119251,0.025961698,-0.051278382000000004,-0.087287764,1.201765173,2.357535951,-4.51601823,-5.9294625320000005,-3.4723018039999998,-3.2711240619999997,-5.766464394,-4.140738358,-4.753816644,-1.972144633,-1448.7431182297878 -2650,2650,W163L,-0.005738165999999999,-0.017272036,-0.010926389,-0.019421487,-0.240498541,-0.065915422,-0.00222784,-0.009248491,0.026852222999999998,-0.031701649,-0.0028424229999999997,-0.023952077999999998,0.002099301,-0.03093215,-0.007910824,-0.219883572,-0.26111350899999997,1.298661257,1.9812062380000002,-4.041255077,-5.426585693,-2.683202675,-3.3566309889999997,-5.819443794,-2.9204122310000002,-4.422816616,-0.963830443,-1443.7058778190985 -2651,2651,W163N,-0.035596295,-0.000848432,-0.01498105,-4.1e-05,-0.20943181100000002,-0.096141014,-0.044082484000000005,-0.027110105,0.028833241000000003,0.0030068390000000003,-0.004703702,-0.008604131,-0.021357967999999998,-0.011583825,0.011501892,-0.196830007,-0.222033614,1.3661810580000002,2.096238498,-2.741142307,-3.919673538,-1.696096794,-2.140633743,-3.26898317,-2.680324287,-3.751011301,-0.622034493,-1445.8379790517502 -2652,2652,W163Q,0.028755978999999997,0.013221041000000001,0.018205583,0.003915841,-0.35566712799999994,-0.075654338,0.04726543,0.010246527,0.039989952,0.031741962,-0.00529988,0.004613625,0.03179754,-0.02537953,0.033211211000000004,-0.27853461399999996,-0.432799641,1.5592541469999999,2.155940437,-4.636570882,-5.0557308039999995,-3.836182777,-5.228609634,-4.728254456,-4.334076736,-4.643901428,-2.981449477,-1436.5825219997205 -2653,2653,W163P,0.009120472,-0.02635468,-0.004832039000000001,-0.013349479,-0.605318946,-0.0579525,0.0075217209999999994,0.010719221999999999,0.027258865,-0.027033165,-0.025676194,-0.038973999,0.029309921,-0.042592812,0.015893855,-0.487806109,-0.722831782,1.311143135,1.726085232,-4.895965512,-6.14794355,-3.84308828,-4.648128693,-5.622339408999999,-4.218327629,-4.79332921,-1.261463893,-1437.1629502922297 -2654,2654,W163S,0.036677386,-0.0016396479999999998,0.007884911,-0.0034788370000000002,-0.340141466,-0.048247998,0.048088381,0.02526639,-0.006405619,-0.004025397,0.0007461010000000001,0.0063504419999999995,0.00941938,-0.037140276,0.030182602000000003,-0.28406860899999997,-0.396214322,1.7996795230000002,2.299866525,-5.467296619,-6.285222678999999,-3.731226402,-5.012857521,-6.345606651000001,-5.961569839,-5.502603165,-1.431180778,-1437.6208988646977 -2655,2655,W163R,0.0054144219999999995,0.005021383,0.01892314,0.0039578090000000005,-0.27588543600000004,-0.043200888,-0.003029639,0.013858483000000001,0.022698394,-0.009082549,0.019125315,0.020917291,0.016928989,-0.005311059,0.013226676000000001,-0.235232763,-0.316538108,1.589341757,2.2147864680000002,-2.203317815,-3.0597011110000003,-1.305087616,-1.9336207280000002,-3.046082634,-1.672096985,-3.799333137,-0.455727836,-1427.940067148069 -2656,2656,W163T,0.026030697999999998,-0.00950633,0.018414281,-0.008092335,-0.19232654899999999,-0.042025362999999996,0.040276062,0.011785334,0.044459107000000005,-0.018191881,-0.0008207789999999999,0.015689248,0.021139314,-0.037361264,0.021176595,-0.163657854,-0.22099524399999998,1.3999701709999999,2.161120397,-2.860510988,-3.299626335,-1.190045647,-2.176510834,-4.291277802,-3.345094322,-3.367915352,0.035773602,-1444.845216835849 -2657,2657,W163V,-0.012845111000000001,0.003346084,-0.03357242,-0.022842559,-0.158162042,-0.033819977,-0.013786516,-0.011903705,0.028684072,-0.006799105,0.013491272,-0.024645418,-0.042499420999999996,-0.031542957,-0.014142161,-0.140497361,-0.17582672300000002,1.487756609,2.299630945,-4.437708655,-5.883965003999999,-3.386404114,-3.747049347,-5.040678932,-4.130445877,-4.502405871000001,-1.985671467,-1444.4330921713263 -2658,2658,W163Y,0.02722189,-0.0030464940000000003,0.01867395,0.005171987,-0.110791918,-0.08993173199999999,0.042378158,0.012065621,0.033166042,0.01120954,-0.017302528,0.019897462,0.017450438000000002,0.025115977999999997,-0.014772005,-0.067840142,-0.15374369300000001,1.233653721,2.383984478,-2.830430898,-3.969158829,-2.220497475,-2.699337395,-2.323745209,-2.9394155810000004,-3.3874585919999998,-0.467958473,-1452.9303974141367 -2659,2659,E164A,0.060081527999999995,-1.612476742,-2.264349123,-2.192751981,-3.2218152160000004,-0.043044177,0.06828318400000001,0.051879872,-0.086693326,-1.669124241,-1.555829242,-2.347685213,-2.181013032,-2.155222551,-2.23028141,-3.0907137380000003,-3.3529166939999997,-0.163810327,-1.077986141,-9.986277783,-9.777449875,-14.84284362,-9.440222473,-8.978788147000001,-6.892084801,-6.736497347999999,-4.056130563,-1448.2517559989356 -2660,2660,E164C,0.042852698,-1.8898592,-2.475895522,-2.272275165,-3.04428599,-0.12652358,0.06673181,0.018973586,-0.075213509,-1.937131955,-1.842586445,-1.97887083,-2.972920213,-2.154384953,-2.3901653769999998,-2.7218993539999996,-3.366672626,-0.420073284,-1.137605922,-14.83487093,-15.15025117,-19.821886399999997,-13.92187298,-14.22212894,-11.05821514,-9.509415575,-5.173556779,-1455.752860493958 -2661,2661,E164D,-0.007808159,-0.862277112,-1.4364562969999999,-1.866212101,-2.074786308,0.140039246,0.064298429,-0.07991474700000001,0.012151186000000001,-0.873595235,-0.8509589879999999,-1.408249632,-1.464662961,-1.935946273,-1.7964779290000001,-1.929429406,-2.220143209,4.265619212,2.51794917,-9.415001616,-9.728662399,-12.64203629,-7.78894162,-8.804949509,-8.110418266,-7.339123221,-3.612970264,-1446.895809440408 -2662,2662,E164G,-0.01671895,-1.4969065769999998,-2.046241694,-2.318558303,-3.05785632,0.21739662899999998,0.018817143,-0.052255042,-0.13929654800000002,-1.588389565,-1.405423589,-2.001965646,-2.0905177409999998,-2.142717663,-2.494398943,-2.670360552,-3.445352087,0.644588947,-0.9257344470000001,-13.25631682,-12.53022195,-14.93158228,-14.52949016,-12.15780497,-12.13248476,-7.68726208,-4.303261268,-1447.925678738393 -2663,2663,E164F,0.047813307,-1.671370539,-2.0734184680000003,-2.553786504,-2.825797328,0.671854585,0.10723386300000001,-0.01160725,-0.19334970199999998,-1.586414176,-1.7563269019999999,-2.4063043,-1.740532635,-2.104697169,-3.002875838,-2.371181574,-3.280413082,0.049409217000000005,-1.09447395,-14.74076965,-16.14969238,-21.10988087,-13.03793656,-12.92461571,-10.48172276,-7.301922069,-3.3752715139999996,-1451.7091068588197 -2664,2664,E164I,0.045687699000000005,-1.75360409,-2.3880954180000002,-2.6844750619999997,-2.868440257,-0.028313282999999998,0.063659295,0.027716102000000003,-0.09656561699999999,-1.9682673640000001,-1.538940816,-2.010006239,-2.766184597,-2.486550358,-2.882399765,-2.576943504,-3.1599370089999996,-0.951815022,-1.149341479,-16.12982331,-16.01400848,-23.66417783,-14.72477146,-14.92762304,-11.31853572,-7.202635244,-2.84127593,-1446.5746023682877 -2665,2665,E164H,-0.017968573,-1.4953735819999998,-2.037760335,-2.8993068639999997,-3.233787056,0.319599769,0.028954011,-0.06489115599999999,-0.071897395,-1.60822971,-1.3825174530000002,-2.17284733,-1.90267334,-2.524452713,-3.2741610139999997,-2.915875854,-3.551698258,-0.171126709,-1.027088092,-12.99250601,-13.59337513,-18.60009975,-10.53248678,-13.81210065,-8.424467766,-7.643004972000001,-5.665809293,-1454.500170017127 -2666,2666,E164K,0.07764884799999999,-0.9649074609999999,-1.8048512819999998,-2.709972898,-2.893938093,0.261358198,0.136223798,0.019073897,-0.052096634,-1.192838972,-0.73697595,-1.933547851,-1.676154713,-2.586183229,-2.8337625660000003,-2.676576375,-3.11129981,0.637961867,-0.692884232,-12.12417852,-14.08195161,-15.0365836,-11.27590714,-10.23982819,-9.986622047000001,-7.924268873,-4.6712608289999995,-1458.3404529271647 -2667,2667,E164M,-0.07061345299999999,-1.76490504,-2.454504108,-2.8389293810000003,-2.8723795780000003,-0.05941116,-0.061668968,-0.079557937,-0.148565211,-2.0765004069999997,-1.4533096719999998,-2.4192692780000002,-2.489738937,-2.594783401,-3.08307536,-2.3841465509999997,-3.360612604,-0.523940497,-1.198749995,-16.28372884,-16.37340189,-23.49623007,-17.28861965,-13.46835154,-10.79204105,-7.841701523999999,-1.6495750530000002,-1450.2910357834771 -2668,2668,E164L,0.033686007000000004,-1.6406609369999998,-2.084481891,-2.199711708,-3.3575570939999997,-0.07898183,0.076089691,-0.008717677,-0.109367785,-1.7220767780000001,-1.559245095,-2.219747608,-1.949216174,-2.094231735,-2.305191681,-2.8536316619999997,-3.861482526,-0.0738483,-1.077391623,-16.5373069,-15.47368821,-25.50088382,-16.15609193,-15.90736565,-9.648504875,-7.76554407,-1.825243809,-1448.1087069455534 -2669,2669,E164N,0.070888483,-1.519066213,-2.054373714,-2.549723362,-2.321734186,-0.015868095,0.100831856,0.040945109,-0.183928833,-1.843146495,-1.19498593,-1.583855374,-2.5248920530000003,-1.981218247,-3.118228476,-2.247702652,-2.39576572,-0.19680047399999998,-1.097205403,-13.77679116,-13.08011882,-20.64650765,-11.46499214,-13.78201531,-9.910321892,-8.374249392000001,-5.6974776,-1444.3753106277436 -2670,2670,E164Q,-0.023614264,-1.5791390419999998,-2.607478655,-2.753343301,-2.9373084960000004,0.081904883,0.008414102,-0.055642629000000006,-0.171909002,-1.7038863469999999,-1.454391737,-2.347685213,-2.867272096,-2.523199337,-2.983487264,-2.613592483,-3.261024508,0.028323947999999998,-1.114274362,-10.36497338,-10.38402042,-14.54017455,-10.09036394,-8.302261192000001,-8.508046783,-8.209619257,-4.6209597769999995,-1448.6267291228287 -2671,2671,E164P,0.013400888,-1.594031721,-2.05750879,-2.298539285,-3.133019478,0.779437498,0.013449474,0.013352301,-0.135692506,-1.65230214,-1.5357613019999998,-2.244948484,-1.870069096,-2.374705116,-2.2223734530000003,-3.1640682669999998,-3.101970688,0.129210937,-1.063470648,-13.99691298,-13.26590295,-20.714085,-13.18403093,-11.41228649,-11.40825954,-7.080408718999999,-3.991932528,-1458.4228215110488 -2672,2672,E164S,0.07998695,-1.51626711,-2.03562332,-2.570563591,-3.0186656739999997,-0.029009699,0.089032031,0.070941869,-0.127538086,-1.556707249,-1.47582697,-2.162717554,-1.908529085,-2.162140418,-2.978986763,-2.604716082,-3.4326152660000004,0.160209508,-1.008871423,-11.28197355,-11.86368515,-14.71403962,-10.76322996,-10.61644279,-8.452470222,-7.489372744,-4.554672735,-1450.7386504183523 -2673,2673,E164R,0.024984801,-1.575212651,-2.063286221,-2.367241537,-3.21360509,0.25047407,0.061539736,-0.011570134,-0.048808402,-1.6690907680000002,-1.4813345340000001,-2.108769651,-2.01780279,-2.1703404230000003,-2.56414265,-2.77261693,-3.65459325,-0.23383806399999998,-1.06432715,-12.85866729,-16.97799489,-17.48598087,-11.89997205,-10.89856807,-7.030820541000001,-7.504945356,-3.74604217,-1458.1841413741931 -2674,2674,E164T,0.010001866,-1.610440827,-1.859895778,-2.660752843,-2.9327636669999997,-0.001658881,0.025253742000000003,-0.00525001,-0.100629596,-1.6954367719999999,-1.525444882,-1.9712588519999998,-1.7485327030000002,-2.389811025,-2.9316946610000003,-2.7812341660000004,-3.0842931680000003,-0.146316878,-1.083531939,-12.77417935,-12.48618042,-16.62658763,-12.8216103,-12.288056800000001,-9.648461594,-7.364157477999999,-2.591350626,-1447.5415547164157 -2675,2675,E164W,0.019793274,-1.743472752,-1.94107118,-2.089505645,-3.386125481,0.38113443,0.05830954,-0.018722993,-0.12484927800000001,-1.7306580669999998,-1.756287437,-2.1148196230000003,-1.767322736,-2.086213763,-2.092797526,-3.079696896,-3.692554065,-0.07923592900000001,-1.096493081,-16.60174596,-16.59210052,-24.01899975,-14.635981099999999,-15.18935376,-12.57229465,-9.281906954,-6.9072445039999995,-1454.9072779142298 -2676,2676,E164V,-0.000619346,-1.63607516,-2.370896214,-2.6778705069999997,-2.972760077,0.027243369,0.032563102999999996,-0.033801793999999996,-0.093644343,-1.751847366,-1.5203029540000002,-2.3164649859999997,-2.425327441,-2.668070369,-2.687670645,-2.758463515,-3.187056638,-0.320547108,-1.0962405000000002,-15.05635287,-15.98477374,-22.33514816,-15.28839175,-13.15785397,-8.515596741,-7.401599207,-2.541422135,-1448.7526798448525 -2677,2677,E164Y,0.03419084,0.02249866,-0.250997542,-2.16514141,-2.8886972280000003,0.38077883,0.044170005,0.024211675,-0.08053550799999999,-0.018462261,0.06345958,-0.401525726,-0.10046935800000001,-1.957251092,-2.373031728,-2.348674233,-3.428720222,1.509662845,0.727258264,-13.05504209,-12.47342389,-15.85017612,-12.24386271,-13.67717688,-11.03057085,-7.910881037999999,-4.914496409,-1454.3211961197667 -2678,2678,P165A,-0.016733368000000002,0.007880625,-0.034554958,-0.043266222,-1.173297695,0.034138603999999996,0.009538584000000001,-0.04300532,-0.062866577,0.002791609,0.01296964,-0.043286331,-0.025823584,-0.04922396,-0.037308483999999996,-1.074569156,-1.2720262340000001,0.7889830640000001,1.360357597,-5.439867134,-5.34206955,-6.32000222,-4.779540894,-5.812777702000001,-4.944945305,-6.015881912,-1.997706994,-1454.2712224312127 -2679,2679,P165C,-0.027506983999999998,-0.005332266,0.005881785,-0.018828128,-1.21695688,0.11934187800000001,-0.015400974,-0.039612993,-0.049711029000000004,-0.020762888,0.010098356,-0.031627853,0.043391423,-0.04121098,0.0035547240000000004,-0.9955328109999999,-1.4383809490000001,0.877315521,1.38499411,-10.35793833,-10.29139707,-10.846954199999999,-9.935764282000001,-10.25413562,-10.46144045,-8.575837471,-6.433138002000001,-1459.5438361284323 -2680,2680,P165E,-0.050869929,-0.068533198,-0.034488838,-0.013063191000000002,-1.695484262,0.06243829099999999,-0.049110449,-0.052629407999999996,-0.152343413,-0.014385442,-0.12268095400000001,-0.045382689000000004,-0.023594987,-0.022493079,-0.003633303,-1.599415826,-1.791552697,0.592780347,1.309902125,-6.655948991,-5.554859108,-6.3817614979999995,-6.417485451,-8.71442318,-6.211215721,-6.028212777999999,-1.389311094,-1443.1404734859243 -2681,2681,P165D,-0.025071542999999998,0.002011079,0.045051231,-0.013742967,-1.556104221,0.096454195,-0.048090737,-0.0020523489999999998,-0.043322188,0.044492372999999995,-0.040470215,0.065763029,0.024339432,-0.010674099,-0.016811835,-1.430204906,-1.682003535,0.81676416,1.333682387,-8.603315869,-7.89198024,-9.719175156,-7.822255408999999,-9.803118416,-7.780050125,-6.842423371000001,-2.484471346,-1450.099803141784 -2682,2682,P165G,-0.00819141,-6.22e-05,0.020981296,-0.017634149,-1.984731056,0.5119298870000001,-0.014370118999999999,-0.0020127,-0.024571737000000003,-0.010564631000000001,0.010440258000000001,0.013827533999999999,0.028135057,-0.019376455,-0.015891843,-1.612710189,-2.356751922,0.8211996640000001,1.323318012,-6.557051443,-5.797379967,-7.371419158999999,-5.583146393,-7.423402077,-6.609909622000001,-4.3890053810000005,-2.33455074,-1448.9293139809743 -2683,2683,P165F,-0.01085904,0.019954104,-0.015868725,-0.406435173,-2.2579569999999998,0.010724588,0.00905794,-0.030776018999999998,0.002236849,0.035793591,0.004114617,-0.012309196000000001,-0.019428253,-0.334958944,-0.477911401,-2.1271868659999997,-2.388727133,1.423129076,1.3201015520000001,-10.49646352,-11.37263591,-11.40585867,-10.29292464,-9.39954377,-10.01135462,-7.016608565,-3.723470471,-1458.9224547119811 -2684,2684,P165I,-0.08305615400000001,-0.097487041,-0.06583080599999999,-0.026895758999999998,-0.527164155,0.087868882,-0.065145226,-0.100967081,-0.121657413,-0.101440838,-0.093533243,-0.055150990999999996,-0.076510621,-0.077780985,0.023989467,-0.48736758,-0.5669607289999999,1.4833693980000002,1.833297393,-5.878281656,-7.265974655,-5.241792908,-5.763110427999999,-5.142780548,-5.977749741,-5.399850107000001,-3.383961555,-1451.0234656617977 -2685,2685,P165H,-0.028253211,0.074433425,0.037302612,-0.0033447729999999997,-1.577464349,0.06861828,-0.027767151,-0.028739271,-0.085304331,0.10366511,0.045201739000000005,0.063479522,0.011125702,0.037103376,-0.043792921,-1.687485874,-1.467442823,0.550480827,1.311128903,-11.30406255,-10.45648767,-12.17027256,-10.72555392,-11.82903829,-11.33896029,-6.4196512939999995,-4.209086751,-1462.3788383631036 -2686,2686,P165K,-0.077917685,0.01561813,0.048688664000000006,-0.023009987000000003,-1.4789790369999998,0.087393433,-0.080474196,-0.075361173,-0.04686832900000001,0.04081352,-0.009577261,0.06943408,0.027943247999999997,-0.057194842,0.011174868999999999,-1.287357979,-1.670600095,0.8722444140000001,1.35109225,-7.859878687999999,-7.521869095,-8.293712059,-7.52424176,-8.017999496,-7.94157103,-6.183537599999999,-2.8385696210000004,-1452.9581528627314 -2687,2687,P165M,-0.06203848,0.032466781,-0.016022998,-0.01479749,-1.40629147,0.064640505,-0.056152818,-0.067924141,-0.017893304,0.09360106300000001,-0.028667501,0.027576097999999997,-0.059622093,-0.005336723000000001,-0.024258257000000002,-0.926049954,-1.886532986,0.7054294320000001,1.362729995,-7.033396741000001,-8.282557938,-7.707186432,-6.9164458689999995,-6.0927047729999995,-6.168088692,-5.743922281000001,-1.23292792,-1456.2309100655839 -2688,2688,P165L,-0.052139845,-0.030492476,-0.004881636,-0.0492441,-0.353187675,0.077862419,-0.030475515,-0.073804174,-0.037516667999999996,-0.017925639,-0.043059312,-0.011190511,0.00142724,-0.069927285,-0.028560914,-0.330801969,-0.37557338,1.639272118,2.1064305269999997,-5.303714005,-5.911280426,-5.80230069,-5.918609107999999,-3.99254702,-4.893832778999999,-4.59204158,-2.6580992119999998,-1449.5721906060353 -2689,2689,P165N,-0.101002375,-0.047014558,-0.050951410999999995,-0.029849685,-0.771029889,0.12393356900000001,-0.083691858,-0.11831289099999999,-0.093427861,0.002174404,-0.096203519,0.000890953,-0.102793775,-0.014487238000000001,-0.045212132,-0.6962331829999999,-0.845826595,0.8988129020000001,1.44151548,-9.085535353,-8.259350449,-8.807022636000001,-9.00291597,-10.35720254,-9.001185173,-6.809225285,-4.081631892,-1460.633868105244 -2690,2690,P165Q,-0.049024242,-0.032043953,-0.016391273999999997,-0.035589283,-1.4011301680000001,0.11882595300000001,-0.026089453,-0.07195903,0.01105237,-0.05505103099999999,-0.009036875,-0.04377054,0.010987992,-0.08856547699999999,0.017386911,-1.400062259,-1.402198076,0.8778117940000001,1.34188831,-7.5853816510000005,-6.856364731,-7.2980574339999995,-7.996603378,-8.200913101,-7.574969612,-5.935129142,-3.2067370110000004,-1452.187092914246 -2691,2691,P165S,-0.025469442999999998,-0.001371008,-0.014335531,-0.022500626,-1.27638993,0.096454717,-0.015835167,-0.035103719,-0.07283745400000001,0.007983579000000001,-0.010725595,-0.025443989,-0.003227073,-0.028796255,-0.016204997,-1.052852307,-1.499927553,0.734930165,1.355711725,-6.075066382999999,-5.829662537000001,-6.144133148,-5.5774188229999995,-6.951619292999999,-5.872498116,-5.761526514,-3.420295173,-1460.9837401169352 -2692,2692,P165R,-0.048184529000000004,-0.001356164,-0.031512507,-0.02700193,-1.540979088,0.093436315,-0.034464369,-0.061904688,-0.075911142,-0.005726846999999999,0.0030145190000000002,-0.036748525,-0.026276489,-0.033197566,-0.020806294,-1.490084126,-1.59187405,0.87453776,1.3360578920000001,-8.215258452,-8.510146393,-6.630752304,-8.631724472,-8.76505162,-8.53861747,-6.050950092000001,-1.666131033,-1457.8460501767695 -2693,2693,P165T,0.005106602,-0.011358968999999998,0.011091829,-0.052929989000000004,-0.07192525,0.18885133699999998,0.001738694,0.008474509,0.015913881,-0.039608596,0.016890659,-0.011741702,0.03392536,-0.069964177,-0.035895800000000005,-0.067439057,-0.076411442,1.3394774040000001,2.3829762480000003,-0.7391094559999999,-1.4596145630000001,-0.833903107,-0.039168251,-0.6712362140000001,-0.691625145,-0.48366884299999996,-1.124361004,-1465.9572200034745 -2694,2694,P165W,-0.060405824000000004,-0.035290598,0.0007291089999999999,-1.033370532,-2.673980819,0.10259163,-0.038408606,-0.082403041,-0.052964187,-0.037211011,-0.033370184,0.018639026,-0.017180808,-0.90585557,-1.1608854929999999,-2.25562861,-3.092333027,1.944259419,1.355310934,-11.332984800000002,-11.51044146,-11.86488109,-11.13626993,-10.78120815,-11.37212335,-7.9845478320000005,-5.758762842,-1459.113229432609 -2695,2695,P165V,0.035725667,-0.016343426,0.021251806,-0.005679023,-0.337033628,0.12288474699999999,0.039732766,0.031718567,-0.032393622999999996,-0.031516981,-0.00116987,-0.004236597,0.046740208,-0.057212106,0.045854060999999995,-0.328455505,-0.34561175,1.3882191680000002,1.906566134,-5.286228102,-6.600841461,-4.5662672419999994,-5.57330162,-4.637094635,-5.053635551,-4.763265908999999,-3.452250285,-1451.1472674785182 -2696,2696,P165Y,-0.05969833,-0.010500713,-0.021927772,-0.2657837,-2.125045058,0.059893315999999995,-0.084765516,-0.034631143999999996,-0.021487485,0.001063511,-0.022064936,-0.038038031,-0.005817513000000001,-0.174348417,-0.357218983,-1.83168232,-2.418407796,1.182857733,1.336381752,-11.43221446,-11.899652900000001,-12.47692651,-10.72964124,-10.12848338,-11.92636829,-6.538755134,-4.065942387,-1460.1579380389303 -2697,2697,E166A,0.028897534,0.053025132999999995,0.027068808,0.015776523,-0.011919645,-0.039928032,0.022350953,0.035444115,0.01660418,0.058270712999999995,0.047779552999999995,0.025041817,0.029095798,0.020240908999999998,0.011312137,-0.010822328999999999,-0.013016961,1.200270332,2.547443944,-1.2554742,-1.019653687,-1.175729828,-1.3899512019999998,-2.28187011,-0.410166176,-1.7526302619999998,-1.177230575,-1453.1957910754718 -2698,2698,E166C,-0.045742172000000005,0.015361678,0.00329139,-0.017483942,-0.058989229000000004,0.042248658,-0.062503449,-0.028980894,0.008122436,0.058928220999999996,-0.028204865,0.04375141,-0.03716863,0.000474356,-0.035442239,-0.02716621,-0.09081224800000001,1.266356399,2.540481288,-7.867562567,-8.238912063999999,-6.461035461,-8.170910088,-8.914844414,-7.552110809,-9.087975262999999,-9.120583477,-1454.4117127545178 -2699,2699,E166D,0.050109756,0.053185069,0.025114711,0.03902202,0.0055922459999999995,0.010924678,0.033129529,0.067089982,0.048700720999999995,0.049754575,0.056615563,0.003071688,0.04715773400000001,0.061157715,0.016886325,-0.023748325,0.034932817000000005,1.247305402,2.690587958,-1.558416658,-1.6140271990000001,-1.0665284879999999,-2.273651215,-1.899801384,-0.938075005,-2.6296255719999997,0.104510265,-1452.5602236771956 -2700,2700,E166G,-0.000124314,0.048933150999999994,0.010628576,0.012021878,-0.060012719000000006,0.02457081,-0.009734024,0.009485396,0.030882696,0.073761315,0.024104987,0.031874634,-0.010617482,0.055789270999999994,-0.031745515,-0.045158023,-0.07486741400000001,1.359022036,2.750051038,-3.504978767,-3.954187805,-2.612458504,-3.9655043869999997,-4.609133415,-2.383609726,-4.198108028,-1.85002317,-1447.129430548288 -2701,2701,E166F,-0.030926282000000003,-0.006136848,-0.057421625999999996,-0.012560358,-0.047233269,0.0044261909999999995,-0.023937201,-0.037915363,0.057084392000000005,0.047670141,-0.05994383599999999,-0.048494753,-0.06634849799999999,0.009541683,-0.034662398,-0.021271756,-0.073194781,1.313536315,2.5357030959999998,-5.32225546,-6.378616882,-3.845511887,-5.8559558329999994,-5.809816452000001,-4.721376244,-5.408989424,-4.146250001,-1443.3346233358607 -2702,2702,E166I,0.06821282099999999,0.009041805,0.07331724099999999,-0.021082512,-0.12248105699999999,0.017751235,0.062237392,0.074188249,0.099266386,0.012979629,0.00510398,0.062207407,0.084427074,-0.007386076,-0.034778948,-0.141486936,-0.10347517699999999,1.4258734830000002,2.2779851840000003,-6.743083907999999,-7.1448594210000005,-4.6763070980000006,-6.842818619,-7.413378426,-7.6380559770000005,-5.867705282999999,-3.635250767,-1444.1059421841055 -2703,2703,E166H,0.064472407,0.051440066,0.040566516000000004,0.027583492,0.05818229900000001,0.039333807,0.05801755,0.070927263,0.018967839,0.091067262,0.01181287,0.057981532,0.0231515,0.058973315,-0.0038063309999999996,0.05307161,0.063292988,0.982773914,2.721089062,-4.3961254069999995,-3.478350189,-2.777450661,-5.111515839,-5.914437775,-4.698872574,-5.08801418,-3.227800228,-1449.5632126200944 -2704,2704,E166K,0.020863923,0.020961004,0.014419564,0.02774677,-0.058571476,0.03636585,0.028522177000000003,0.013205668,0.046108764,0.029813107999999998,0.0121089,0.015182768999999999,0.013656359,0.036830009,0.01866353,-0.037009349,-0.080133602,1.226266326,2.521170292,-4.167360892,-5.2637084960000005,-2.7437820360000003,-4.016729233,-4.565670715,-4.2469139789999995,-4.75153837,-2.923080742,-1445.5051968488842 -2705,2705,E166M,-0.035666653,0.036783627,0.049154719000000006,0.010634656999999999,0.0037124809999999997,0.016741465,-0.059572027,-0.011761278,0.026132807999999997,0.10371128,-0.030144027,0.078167087,0.020142351,0.033558524,-0.012289211000000001,0.040133707000000005,-0.032708745,1.1101980409999999,2.8497304039999998,-5.1117846280000006,-5.185610504,-3.5983088530000003,-5.524823242,-6.152654838999999,-5.0975257030000005,-5.347416013,-3.727191659,-1447.0377785568126 -2706,2706,E166L,0.01323957,0.038615914,0.014330124,-0.003781048,-0.040056983,-0.049241371,0.007776205,0.018702933999999997,0.022666707,0.06609844,0.011133388000000001,0.016738469,0.011921778999999999,0.015639879,-0.023201974,-0.040721501,-0.039392464,1.217689593,2.419237274,-4.712764226,-4.465135078,-2.748326004,-4.867181625,-6.12572052,-5.357457901,-4.345703609,-2.8497774319999998,-1445.4941222793423 -2707,2707,E166N,-0.042662335999999995,0.015499862,-0.005370071,-0.004348513,-0.069317183,0.012366294,-0.035269206000000004,-0.050055465,-0.0031013,0.05670018,-0.025700456,0.077285521,-0.088025663,0.069957832,-0.078654858,-0.020284215,-0.11835015,1.16455779,2.53594446,-4.928578003999999,-5.743958999999999,-3.646906555,-5.044894783,-5.570473991,-4.636655693,-5.389385582,-3.809826025,-1442.797955823131 -2708,2708,E166Q,-0.015855998,0.026265542000000003,-0.016725943,-0.007830972,-0.021115558,-0.022885249,-0.037881654,0.006169659,0.045396228,0.04722965,0.005301433,-0.010249882,-0.023202004,0.003709939,-0.019371882,-0.034116221,-0.008114895,1.326265902,2.462686796,-3.3926861130000003,-3.447271423,-2.0301643830000002,-4.01893441,-3.603532982,-3.863527367,-4.681928339,-1.978431199,-1450.9555387580767 -2709,2709,E166P,-0.032698756,0.01452947,-0.006200669000000001,-0.051852342999999995,-1.836023503,0.032343397,-0.04542116,-0.019976352,0.011147289,0.045179547,-0.016120607,-0.009107444000000001,-0.003293893,-0.020813028,-0.08289165700000001,-1.672281006,-1.999766,0.62787574,1.307767011,-6.476953256,-6.499234137999999,-4.0388834760000005,-7.15712458,-8.492500786,-6.1970233,-6.848003815,-3.881706204,-1448.174721288029 -2710,2710,E166S,0.020317328,0.022279259,0.00918526,0.008188421999999999,-0.030948467,0.043227695,0.016488581000000002,0.024146074,0.00110348,0.05588664,-0.011328122,0.041843775,-0.023473256,0.031312917,-0.014936073999999999,-0.033723372,-0.028173561,1.152808179,2.4280021830000003,-2.4960743969999997,-2.228454887,-1.6417329790000001,-2.8108784260000004,-3.4663418580000003,-2.332963837,-3.0168554660000004,-2.333488209,-1445.385845432058 -2711,2711,E166R,0.008139333,0.027227097000000002,0.010429474000000001,0.008978958,-0.072704092,0.027905789,0.011953915,0.004324751,0.011267768999999999,0.059387225999999994,-0.004933033,0.019658111000000002,0.001200837,0.03211004,-0.014152125,-0.08894807800000001,-0.056460105,1.173860591,2.2452317269999997,-5.364735696,-5.849258598,-2.738401619,-6.105006691,-6.537979117999999,-5.593032455,-5.617802913999999,-2.582419616,-1444.5361028001644 -2712,2712,E166T,0.012194587,0.027449286,0.01491156,-0.006641364,-0.043164957000000004,0.058641425999999996,-0.00021674599999999997,0.024605919,0.029566947000000003,0.018362755,0.036535816,0.014457191999999999,0.015365927,0.006600541,-0.019883269,-0.07259840099999999,-0.013731512,1.2045483209999999,2.313700915,-1.9546295809999998,-1.848165405,-1.540262451,-1.997500145,-2.8600383989999996,-1.5271815030000002,-3.2449866989999996,-1.762482719,-1442.8500925670378 -2713,2713,E166W,0.039062322999999996,0.044336457,0.0319567,0.034112628,-0.022417454,-0.006991553,0.025514585,0.05261006,0.061514633,0.049587385,0.039085528,0.030020903999999998,0.033892496,0.018545402,0.049679852999999996,-0.047856855,0.003021947,1.370318051,2.4874263709999997,-7.692036961,-8.595013855,-5.073739388,-8.598346634,-8.509689446,-7.683395485,-7.139362656,-4.803275952,-1454.0451839324087 -2714,2714,E166V,-0.0469483,-0.018338363,-0.014486171,-0.020546363,-0.109649546,-0.003023596,-0.061429827,-0.032466773,-0.003226234,0.009109746,-0.045786472,0.017153182,-0.046125523,0.00140831,-0.042501036,-0.128059179,-0.091239913,1.272030866,2.155326384,-5.3140160860000005,-5.894460182,-3.485250671,-5.667102036,-6.490270821,-5.032996719,-5.619667403999999,-2.9776582730000003,-1446.222037020605 -2715,2715,E166Y,0.054499778,0.069139822,0.030585809,0.037582078,0.067210162,0.029815854,0.054664015,0.054335540999999994,0.028332491,0.076827045,0.061452599000000004,0.030959001,0.030212616,0.048351488,0.026812667999999998,0.02053526,0.11388506300000001,1.042526455,2.77922482,-5.070955985,-4.751033249,-4.00399115,-5.827057097999999,-5.28512278,-5.487575645,-5.062333913,-4.486062198,-1443.3988732877187 -2716,2716,L167A,0.02375616,0.023421772999999996,-0.009327488,0.01719356,-0.9991797370000001,0.10636589,0.015547891999999999,0.031964427999999996,,0.0035803540000000004,0.043263191,-0.03930123,0.020646254,-0.005961933000000001,0.040349052999999996,-0.9030111959999999,-1.095348277,0.933007633,1.409695524,-8.948857176,-15.60677046,-8.645514999,-6.623279076,-8.636686043,-5.232035301,-5.87807309,-2.434138098,-1446.5693386970088 -2717,2717,L167C,-0.009622641999999999,0.009378968,0.009273215999999999,0.019074902,-0.017578104,0.324937707,-0.026464725,0.0072194419999999995,,0.008120038000000001,0.010637897,0.01423978,0.004306651,0.035158349,0.002991455,0.024157897999999997,-0.059314105,1.181087765,2.7348506130000003,-12.66186066,-17.85498299,-11.60480917,-12.03028181,-11.92117337,-9.898055938999999,-9.230988578,-6.4337817479999995,-1461.378671955783 -2718,2718,L167E,-0.02351057,-0.010870129,-1.7664628,-2.019669632,-2.415411747,0.102810013,-0.0034186359999999996,-0.043602504,,0.02053398,-0.042274238,-1.768762994,-1.764162606,-1.822186766,-2.217152497,-2.547997273,-2.282826221,3.3667576280000002,1.680881465,-12.94675976,-19.18140831,-12.54914303,-10.5761946,-13.02590199,-9.401150856000001,-8.100678089,-4.33252842,-1451.8552900310606 -2719,2719,L167D,-0.035346381,-0.01042663,-1.9060365119999998,-2.272300482,-3.000815722,0.129185939,-0.032638352,-0.03805441,,0.04193836,-0.062791619,-1.803261971,-2.008811052,-2.1955042999999996,-2.349096663,-2.921314807,-3.080316636,0.37461203,-0.043607626,-14.98490002,-21.245793300000003,-14.971047199999997,-12.81838144,-13.510502300000002,-12.37877585,-9.886197986,-6.827714681000001,-1451.6509047118016 -2720,2720,L167G,-0.037925805,-0.00047351699999999996,-0.027186255,-1.8189604480000001,-2.5855530840000003,0.12077730800000001,-0.022551943999999997,-0.053299665999999996,,0.0036775270000000003,-0.004624561,-0.054673642,0.000301132,-1.7835424519999998,-1.854378444,-2.509352959,-2.661753208,0.7628183759999999,0.684895182,-13.31886579,-19.06172137,-13.04595895,-11.38772196,-13.09084485,-10.00808182,-7.980194748,-4.051554728,-1449.4636360630393 -2721,2721,L167F,-0.063173033,-0.015112259,-0.07621069,-1.981400465,-2.1411517730000003,0.035127701000000004,-0.045568079000000004,-0.080777987,,-0.032957972,0.002733455,-0.031222862999999997,-0.12119851699999999,-1.9252089209999999,-2.037592009,-2.1281406830000003,-2.1541628630000003,0.656412805,0.665356462,-10.75441684,-13.47082108,-9.614051612999999,-10.12024406,-10.12793063,-10.4390368,-6.878747225,-2.0693424730000003,-1439.3873001234606 -2722,2722,L167I,0.05100575,-0.0034796640000000004,-0.000330755,0.0074301390000000005,-0.034959372999999995,0.065152378,0.059176502,0.042834997,,-0.066577334,0.059618005999999994,-0.050664825,0.050003315,0.007061854,0.0077984230000000005,-0.022589626,-0.04732912,1.235117378,2.449877744,-7.061143477999999,-7.648991347999999,-8.380282127000001,-5.950976272999999,-7.898425507000001,-5.427042137000001,-6.633884124,-2.867073744,-1445.5872761658393 -2723,2723,L167H,-0.034469499,-0.000867085,-1.054665709,-1.9923649959999998,-2.551329907,0.093240387,-0.037262444,-0.031676552999999996,,-0.045055579000000005,0.04332141,-1.223344725,-0.885986693,-2.076317892,-1.9084120999999998,-2.552250926,-2.550408888,2.409891747,0.9979500920000001,-16.64363116,-18.836947,-15.23906696,-18.80386088,-16.22647098,-14.11180997,-9.182611812000001,-5.737775406,-1460.335286122281 -2724,2724,L167K,-0.016945994,-0.43502045200000006,-2.0282116009999998,-2.2077896630000002,-3.034945182,0.109958101,-0.010870506,-0.023021481,,-0.36273882799999996,-0.507302075,-2.379603321,-1.676819881,-2.294724396,-2.120854929,-2.8955961660000002,-3.174294197,0.288556437,-0.46319435600000003,-13.62551021,-18.38776946,-13.93817324,-14.09304472,-11.41351299,-10.29505064,-8.870904918999999,-5.204226364,-1454.3283763504587 -2725,2725,L167M,0.043775427,0.009471524,0.016531342,0.022821049,-0.095031072,0.212735612,0.063928759,0.023622094,,-0.01368415,0.032627197000000004,-0.039293025,0.072355708,0.013170123,0.032471975,-0.11058039199999999,-0.07948175099999999,1.50774049,2.45803467,-4.187371046,-4.031954926,-4.874016167,-4.7982671969999995,-4.337380013,-2.8952369310000003,-5.299544085,-1.444952021,-1452.6163833402097 -2726,2726,L167N,0.012186536000000001,0.004682825,-0.027263979,-0.04314168,-2.83505775,0.206138436,-0.008085061,0.032458132,,-0.012988371,0.02235402,-0.04479086,-0.009737097,-0.055704893,-0.030578467,-2.216881907,-3.453233593,0.794928913,1.283006402,-14.36409107,-20.12345877,-13.15956712,-14.22891618,-13.76821361,-10.54029967,-9.458925519,-5.911648887,-1456.3588324822485 -2727,2727,L167Q,-0.025009842,0.0135106,-0.020932681,-2.180382564,-2.735504062,0.065753485,0.002580647,-0.05260033,,-0.020663875,0.047685074,-0.059283906,0.017418545,-1.7670467669999999,-2.593718361,-2.191827279,-3.279180844,0.725919014,0.683302739,-12.49625469,-19.05752506,-11.08569934,-11.49631896,-11.11901512,-9.722714981000001,-8.047710177999999,-3.448157,-1457.5771457422525 -2728,2728,L167P,-0.039453729,0.035035965,-0.5308229999999999,-2.1130151319999997,-2.538317974,0.076729069,-0.024626535,-0.054280922,,0.047148925,0.022923005,-0.391859358,-0.669786641,-1.978237449,-2.247792815,-2.444410645,-2.6322253019999997,1.452976836,0.708712481,-11.83712751,-17.09582825,-11.10935645,-10.96690076,-10.89037295,-9.123179131,-7.699101584,-4.289282986,-1455.8963412265293 -2729,2729,L167S,-0.014351083,0.005458001999999999,-0.016160984,-1.139683851,-2.662568311,0.076663087,-0.013320123,-0.015382042,,-0.00714593,0.018061933,-0.030257127999999998,-0.00206484,-1.401904049,-0.877463652,-2.424196924,-2.900939697,0.776848578,0.718859603,-9.927176151,-16.21591882,-8.575208069,-8.739439011,-9.445431244,-6.659883606,-6.647556096000001,-3.233205587,-1449.5651850062422 -2730,2730,L167R,-0.034567012,-0.871267569,-2.004142992,-2.256873182,-2.840588155,0.082187305,-0.014647651999999999,-0.054486372000000005,,-0.8370576129999999,-0.905477524,-2.1575964290000003,-1.850689555,-2.1368350030000003,-2.37691136,-2.64876569,-3.0324106189999998,1.557747297,-0.237614016,-13.93177381,-20.18027886,-13.72998726,-13.11189227,-12.67489449,-9.961816154,-8.475420964,-2.8194087000000003,-1456.4907274288125 -2731,2731,L167T,0.020546643,0.025005515,-0.010561272,-0.007957307,-0.880212184,0.10991553300000001,0.027238366,0.01385492,,0.006140019,0.043871010999999994,-0.033236400000000006,0.012113856000000001,0.003372209,-0.019286823,-0.7873875290000001,-0.973036838,0.653128762,1.372324932,-11.27823165,-15.72364294,-11.45486283,-9.830364952,-11.62343649,-7.758851012999999,-8.425423517999999,-2.863191862,-1449.2603743644431 -2732,2732,L167W,-0.027229514,-1.1917113320000001,-2.207127508,-2.420178964,-2.6931647460000003,0.009473129,-0.0065754459999999995,-0.047883580999999995,,-1.250436214,-1.13298645,-2.161196818,-2.253058197,-2.076317892,-2.764040035,-2.677189663,-2.709139828,2.72714215,0.27647041699999997,-14.3268215,-17.92614049,-13.04169379,-14.29523395,-13.742274300000002,-12.62876496,-9.347819131,-5.5559290610000005,-1455.4501502225175 -2733,2733,L167V,-0.021767487000000002,0.013677971,-0.026588597000000002,0.015077031000000001,-0.015985525,0.077525227,-0.04327273400000001,-0.00026224,,0.00029451900000000003,0.027061422999999998,-0.012361772,-0.040815422000000004,0.025083797,0.0050702640000000005,0.002664655,-0.034635705,1.19486694,2.5247538169999997,-6.699480587999999,-7.559443459,-7.721306976,-5.325364723,-7.947934357,-4.943353424,-5.608419897,-2.8931516489999995,-1442.1090797749348 -2734,2734,L167Y,-0.083214775,-1.315170882,-2.01003861,-2.575272585,-2.891833455,0.06711085,-0.055179812,-0.11124973699999999,,-1.199548166,-1.4307935980000002,-1.908204079,-2.111873141,-2.078597659,-3.07194751,-2.9013181789999996,-2.88234873,3.5937918669999998,1.297872375,-14.76272204,-15.8233928,-14.96389929,-14.276420199999999,-13.87926005,-14.87063786,-7.839318619,-3.7008447139999996,-1445.712513034232 -2735,2735,N168A,0.027702993,-0.009094956,-0.03339603,0.005673558,-1.359565393,-0.048446895999999996,0.028305074,0.027100912,,-0.004271942,-0.013917968999999999,-0.073800815,0.007008756,-0.01509123,0.026438345,-1.196243907,-1.5228868780000002,0.9145161070000001,1.366908079,-9.126523216,-7.277275826,-14.09100336,-8.593677681,-8.244965416,-7.425693794,-5.821637629,-2.081454295,-1442.959930491168 -2736,2736,N168C,-0.01325563,-0.012540208999999998,-0.048363623,-0.045854346,-1.797003822,-0.000978153,0.008471856,-0.034983115,,-0.017456994,-0.007623423000000001,-0.057016313,-0.039710933,0.038708237,-0.13041692800000002,-1.430731547,-2.163276097,0.5555748979999999,1.3170926170000001,-14.00026411,-11.64569988,-18.21824418,-13.32504812,-12.911458099999999,-13.90087027,-11.6279856,-9.458422852,-1456.284115226008 -2737,2737,N168E,-3.87e-05,0.00361849,-0.031139855,-1.7639056359999998,-2.469443095,-0.096990281,0.0015094020000000002,-0.001586755,,0.008690409,-0.00145343,-0.040304768,-0.021974941,-1.7257280369999999,-1.8020832340000001,-2.520799312,-2.418086878,0.663799748,0.684787363,-10.86717465,-8.780377304,-16.44189691,-10.96307677,-9.761955612000001,-8.388566635,-7.8519169579999994,-1.686690935,-1457.1397751104087 -2738,2738,N168D,-0.016348783999999998,0.013938262,-0.004908568,0.013362128000000001,-2.229169043,-0.06907743200000001,-0.040028911,0.007331343000000001,,0.003093694,0.024782829,-0.02548714,0.015670003999999998,0.016728998000000002,0.009995258,-1.9488410530000002,-2.509497032,0.730867898,1.300021603,-7.233015862999999,-7.343699432,-9.151473084,-7.307486145,-7.624983475,-4.73743718,-6.998195142999999,-2.41321309,-1454.6903258566745 -2739,2739,N168G,-0.012749712,0.004006979,-0.04231318,-0.012899643,-0.188527075,0.15916433,-0.017537861999999998,-0.007961560999999999,,0.022703462,-0.014689503999999999,-0.048097811,-0.036528549,0.004758706,-0.030557992000000003,-0.1951113,-0.18194285,1.4975640069999998,2.203057435,-7.574360086,-4.861448395,-12.30845545,-7.189318137999999,-7.477850639,-6.034727806,-5.897142595,-3.2108338869999997,-1449.1954650799744 -2740,2740,N168F,-0.036188077,-0.02869126,-2.1760101990000003,-2.138915059,-3.154169562,-0.018014429,-0.022340332999999997,-0.05003582,,-0.008105856,-0.049276664000000005,-2.199173629,-2.1528467680000003,-1.966683135,-2.311146982,-2.8866931460000003,-3.421645977,-0.131676896,-0.31331940399999997,-12.48331656,-11.31033557,-18.82047555,-9.760250328,-9.90349913,-12.62202223,-8.151712283,-3.160304572,-1450.4884245516732 -2741,2741,N168I,-0.030299376,0.011996325,-0.05860076400000001,-0.660491721,-3.003262056,0.034643257000000004,0.019767143,-0.08036589400000001,,0.04412201599999999,-0.020129367,-0.045647692999999996,-0.071553835,-0.569083883,-0.751899559,-2.8782599789999996,-3.128264132,0.737905638,0.828501829,-11.73072959,-9.761129509,-20.05451836,-11.14786073,-9.915852829,-7.774286537,-8.382528459,-4.441771364,-1447.4314720551483 -2742,2742,N168H,0.00226338,0.034605168,-0.016642731,-1.940330186,-2.696715137,-0.000837478,0.018089136000000002,-0.013562376999999999,,0.039432867999999996,0.029777467000000002,-0.039498037,0.006212576,-1.790872518,-2.089787854,-2.318082161,-3.075348113,0.613076965,0.677220232,-10.61410474,-9.311944298,-14.52147174,-10.151797,-9.797473167,-9.287837486,-7.711861316,-1.935051848,-1452.26168394275 -2743,2743,N168K,-0.014803562,-0.081029332,-1.417230798,-1.921767634,-2.398846159,-0.034044146000000004,0.0015303060000000002,-0.031137428999999998,,-0.013153307,-0.148905356,-1.4150791090000001,-1.4193824869999998,-1.9172741709999999,-1.926261096,-2.6032009769999997,-2.194491341,2.774563298,1.23616369,-9.462417322,-8.870437248,-11.11032845,-9.763515137,-9.129233467,-8.438572304,-8.089901953,-2.142169553,-1452.3060892228968 -2744,2744,N168M,-0.039988353,0.052027116,-0.040947177,-0.750830269,-3.19008805,-0.047542327999999995,-0.016914491,-0.063062215,,0.09776131199999999,0.006292919,-0.016877244,-0.06501711,-0.72662886,-0.775031678,-2.893793487,-3.486382612,0.543112768,0.759878215,-11.60186373,-10.09000655,-15.90326514,-11.78889699,-9.566489647000001,-10.66066033,-7.989281047,-4.557547276,-1447.6487397556193 -2745,2745,N168L,-0.012061582,0.040232698,-0.0157709,-1.9264981730000001,-3.2022247989999997,0.022518742,0.000942265,-0.025065429,,0.048384747,0.032080648999999996,-0.016637391,-0.014904408000000001,-1.7803300969999998,-2.072666249,-2.7283688319999997,-3.676080766,0.426496676,0.672897152,-10.71272261,-9.220646628999999,-14.66185291,-11.71016505,-9.79449485,-8.176453606,-7.925686445,-3.257321755,-1439.7313011987135 -2746,2746,N168Q,0.009936038000000001,-0.009388160999999999,-0.033667106,-0.0072938840000000005,-1.962057184,-0.072495285,0.0009637789999999999,0.018908297,,0.00751424,-0.026290562000000003,-0.043939623,-0.023394587999999997,-0.0037316690000000004,-0.010856099,-1.8077925430000001,-2.116321824,0.705691073,1.306688555,-10.56402587,-8.25310379,-12.71518896,-11.40839144,-9.895582031,-10.54786311,-6.2814296579999995,-1.861619819,-1440.8589323284104 -2747,2747,N168P,-0.022543257999999997,-0.053302765,-1.893528171,-2.1196026690000003,-2.963152876,0.096662916,0.0027722579999999997,-0.04785877400000001,,0.039615855,-0.146221384,-1.967007568,-1.8200487730000001,-1.9977585080000002,-2.24144683,-2.6747304709999997,-3.25157528,0.18946537,-0.12401152800000001,-13.40059995,-11.10473385,-20.53084682,-12.63365673,-12.43498397,-10.2987784,-7.467804887000001,-2.978160861,-1456.8311438285746 -2748,2748,N168S,-0.022687142,0.013039978,-0.056499956,-0.024092476,-0.9586709440000001,-0.098234324,-0.019178851,-0.026195432,,0.02993794,-0.003857984,-0.063967312,-0.049032599999999996,0.011596142,-0.05978109400000001,-0.750897956,-1.1664439309999999,0.777474062,1.399002391,-6.071191643,-4.453283234,-8.356821259,-6.044899185,-6.951778618,-4.549175919,-4.9736915139999995,-2.300417911,-1444.1683879881166 -2749,2749,N168R,0.007559675,0.012341681,-0.037646281000000004,-1.4903336919999999,-2.367051715,-0.06163486,0.027784947999999997,-0.012665599,,0.014489463999999999,0.010193897,-0.03317113,-0.042121432,-1.290999049,-1.689668334,-2.1732205,-2.56088293,2.251028355,1.4455556509999998,-13.25856069,-10.63524261,-20.23337785,-11.79845706,-11.98309607,-11.64262983,-7.783224854,-3.235316816,-1451.8515879651532 -2750,2750,N168T,0.021947928,0.022445983,-0.002035756,0.016570587,-1.293284521,-0.004696055,0.036356236,0.007539619,,0.023988056,0.02090391,-0.02548714,0.021415629,0.025294316,0.007846856999999999,-1.212082488,-1.374486554,0.636832294,1.332523842,-6.951776915,-4.4229756469999995,-10.87258549,-6.926874718,-6.748291328,-5.788157394,-5.559235751,-2.635500592,-1446.3038170230575 -2751,2751,N168W,-0.031114617999999997,-0.007513700999999999,-1.021455737,-2.101124509,-2.5586823030000003,-0.007068141,-0.010373081,-0.051856154,,0.031132326000000002,-0.046159728,-0.92742454,-1.115486933,-1.625462281,-2.576786736,-2.1290488780000003,-2.988315727,3.556933064,2.2900382130000003,-14.18874816,-12.68971303,-21.38017712,-11.98573254,-12.41764028,-12.47047782,-9.272486792,-5.834570982000001,-1455.7148440540768 -2752,2752,N168V,-0.036888832999999996,0.013501684,-0.020325594,-0.013474015,-2.083815125,0.011870186000000001,-0.023684443,-0.050093223,,0.010534466999999999,0.016468901,-0.009389774,-0.031261414,0.021047171,-0.047995200999999994,-1.8009547380000002,-2.366675511,0.622444378,1.304458249,-11.02579138,-8.915292519,-19.31251488,-9.910659874,-9.139690224,-7.850799393,-7.495717177,-3.0614458210000004,-1446.1566591705196 -2753,2753,N168Y,-0.012523528,-0.21304340300000002,-1.70179649,-1.97689715,-2.451047804,-0.052862982,-0.007959648,-0.017087408000000002,,-0.13621018199999999,-0.289876623,-1.515299571,-1.888293409,-1.746566369,-2.207227931,-2.026727829,-2.875367778,4.137193597,2.5774732769999997,-13.26626471,-12.16046127,-20.79598386,-10.28164162,-9.793434784,-13.29980202,-7.945561959,-2.920175397,-1451.5777459167875 -2754,2754,E169A,-0.013146613,-0.027920057999999998,0.013182038,0.032935587,0.011510119,0.006481969000000001,-0.011517521999999999,-0.014775703999999999,-0.0049553259999999995,-0.03267412,-0.023165996,0.011726273,0.014637802,0.025267848,0.040603326,-0.0069178569999999995,0.029938094,1.113877919,2.622313949,-5.425133617999999,-5.084872612,-5.823355362,-6.278298256,-5.023430412,-4.915711449,-4.614855783,-0.869946311,-1449.3288125684485 -2755,2755,E169C,-0.044431463,-0.076521512,-0.030147797999999996,0.016529485,-0.23286086,0.153985829,-0.07782533900000001,-0.011037587,0.07927302900000001,-0.040166881,-0.11287614300000001,-0.037949402,-0.022346192999999997,0.042533344,-0.009474375,-0.224149142,-0.24157257699999998,1.272019361,1.9843176230000001,-10.78731823,-10.87660532,-11.29960007,-10.76334898,-10.72244277,-10.274594,-8.906941512000001,-6.470511875,-1445.208770217374 -2756,2756,E169D,-0.117932285,-0.055504745,-0.078598005,-0.012707439,-0.048479077,0.068240287,-0.06462208,-0.171242489,-0.071032834,-0.07859567,-0.032413818999999996,-0.073548938,-0.083647072,-0.020452783000000002,-0.004962095,-0.074395664,-0.02256249,1.35092152,2.335706408,-4.895813481,-5.904384468,-4.861368973,-3.46307386,-5.779126335,-4.47111377,-4.4466693710000005,-1.15204545,-1452.590483690612 -2757,2757,E169G,0.004134853,-0.029662321000000002,-0.003889637,0.003928237,-0.020031158,0.050376515999999996,-0.014144148,0.022413854,0.011000949,-0.037607575,-0.021717067000000003,-0.027503386,0.019724112,-0.005201187,0.01305766,-0.07398067,0.033918355,1.42174823,2.52135041,-8.441202373,-7.957720696,-7.412193405,-9.925747925,-8.321731482999999,-8.588618355,-6.289660337999999,-2.409301656,-1450.9855962325819 -2758,2758,E169F,-0.054640235,-0.027866085,-0.032521503,0.0006438209999999999,-0.224830355,0.477489924,-0.063176471,-0.04610399900000001,0.048538412,-0.049743731,-0.0059884380000000004,-0.034460207,-0.030582799,0.033747459,-0.032459818,-0.181725308,-0.267935402,1.554838161,2.2813231,-9.237172414,-10.43910875,-11.45598996,-6.87928054,-8.529064598,-8.882418221,-6.242579782999999,-3.987417858,-1440.7310085166246 -2759,2759,E169I,-0.040801242,-0.06526406,-0.078477533,-0.050810062,-0.251659858,0.37218655100000003,-0.06984687099999999,-0.011755613,-0.023693974,-0.044489962,-0.086038158,-0.016938198,-0.14001686800000002,-0.014070771000000001,-0.087549352,-0.202314875,-0.301004841,1.354273407,2.091480687,-9.423099571,-9.998399757,-11.65209348,-7.563063057000001,-8.640906548,-9.261035019,-5.107877586,-3.279966917,-1438.3298806399107 -2760,2760,E169H,-0.013537697,-0.030557822999999998,0.0007459389999999999,0.011691958,-0.09894873,0.186106804,-0.035454348,0.008378954000000001,-0.025054632,-0.033811472999999995,-0.027304172999999998,-0.012991273000000001,0.01448315,0.022186229,0.001197687,-0.150576133,-0.047321326,1.435844083,2.2952099919999998,-6.938597821,-8.722697441000001,-8.019606049,-6.31415818,-7.913842155,-3.72268528,-5.664461507,-2.9558791889999996,-1445.7077158666216 -2761,2761,E169K,-0.040393071,-0.051042555,-0.020801313999999998,-0.001990581,-0.030407853,0.04244703,-0.058810975,-0.021975167,-0.066001089,-0.029846359,-0.07223875099999999,-0.052981438,0.01137881,-0.012263484,0.008282322,-0.053348422,-0.007467284,1.200955754,2.2744598330000003,-7.0053848389999995,-8.797671783,-6.331008995,-7.896524086,-6.960222664,-5.0414966660000005,-5.899231788,-1.621503296,-1446.3622067472897 -2762,2762,E169M,0.033258774,-0.003463641,0.029718662000000003,0.011395822,0.021681986,0.028200057999999997,-0.008269683,0.074787231,0.006340732,-0.01084615,0.003918869,-0.0030765590000000004,0.06251388299999999,0.003676408,0.019115235,-0.021945594,0.065309565,1.322020553,2.539203136,-9.331992993,-9.668196526000001,-9.985913588999999,-8.902897858,-8.952965462,-9.149991531,-6.418977655,-4.052849052,-1441.0649998895824 -2763,2763,E169L,-0.007609197,-0.05711495,-0.021691306,-0.0034844790000000004,-0.084152105,0.09332073,-0.043331031,0.028112637000000003,0.035366966,-0.058407115999999995,-0.055822783,-0.025963486,-0.017419125,-0.013539006000000001,0.0065700490000000005,-0.099569128,-0.06873508099999999,1.453277929,2.385105567,-8.538693277,-8.754970505,-10.67597267,-7.2629759289999996,-7.941477218999999,-8.058070061,-5.362389916000001,-2.523386368,-1438.390164946206 -2764,2764,E169N,-0.045041810999999994,-0.025481512,-0.039400113,0.002681044,-0.07560792599999999,0.295262565,-0.032926343,-0.057157278,-0.041923844,-0.033148146,-0.017814878,-0.040954321,-0.037845904,-0.022223878,0.027585966,-0.117819047,-0.033396804,1.379760888,2.238939265,-6.058441847,-7.323574767999999,-6.875054176,-4.5302942889999995,-7.094647949,-4.4686380539999995,-5.4323726,-2.576979176,-1439.2121113236062 -2765,2765,E169Q,-0.083875059,-0.089191428,-0.033969347000000004,-0.023917543,-0.038255578,0.00332058,-0.074309583,-0.093440535,-0.028028169,-0.090824636,-0.087558219,-0.013583635,-0.054355058,-0.008911804,-0.038923282000000003,-0.062441757,-0.014069398,1.254038725,2.341571275,-2.8874430689999997,-3.446541031,-2.830350899,-3.6185327760000003,-2.676539993,-1.865250649,-3.2125868719999997,-1.686121252,-1456.4883540417068 -2766,2766,E169P,-0.096936527,-0.055726847,-0.020217608,-0.141018043,-2.145505745,0.043369785999999994,-0.074502547,-0.119370506,-0.00089823,-0.03770605,-0.073747643,-0.023924852000000003,-0.016510364,-0.07902097400000001,-0.203015112,-2.046973891,-2.2440375980000002,1.069894943,1.307908514,-9.126873437999999,-9.656727425,-7.430089386000001,-9.695175575,-9.536694115,-9.315680687,-6.042519556,-2.00927826,-1451.782488590572 -2767,2767,E169S,-0.058392850999999996,-0.064887789,-0.037797186,-0.022503406,-0.016386098999999998,0.004409585,-0.069649085,-0.047136617,0.010238465,-0.06127796,-0.068497617,-0.043934372,-0.03166,-0.03262013,-0.012386681,-0.05087649,0.018104292,1.124615063,2.223742174,-3.066955905,-2.662507721,-3.064725456,-4.425564362,-2.497074814,-2.684907173,-2.777340221,-0.489856116,-1458.1797107467428 -2768,2768,E169R,-0.034445094,-0.045611207,-0.024138101000000002,-0.003729187,-0.041936411,0.14916386,-0.053449123,-0.015441064,0.006449184,-0.045367887999999995,-0.045854526,-0.03923406,-0.009042142,-0.014258362,0.006799988000000001,-0.091242153,0.007369331,1.432380339,2.3655247619999997,-5.939572345,-8.750249702,-5.629049857999999,-6.963762107999999,-6.282610687000001,-2.072189369,-5.6862078060000005,-0.971105889,-1445.1966312122531 -2769,2769,E169T,-0.04344023599999999,-0.05028254,-0.01517074,-0.004772600000000001,-0.028245622,-0.050022255,-0.060416650999999995,-0.02646382,0.018315986,-0.035126712000000004,-0.065438367,-0.018021348,-0.012320132,-0.013929063,0.004383863,-0.037645767000000004,-0.018845477,1.250002193,2.408237251,-4.4607864930000005,-3.216110893,-4.226266548,-5.2839522169999995,-4.965078125,-4.612524681,-3.131633117,-0.727929292,-1454.829276049044 -2770,2770,E169W,-0.028613757000000004,-0.003827443,-0.007942850999999999,-0.015955636999999998,-0.125559554,0.32242019,-0.045701035,-0.011526479,-0.037558497,0.005600701,-0.013255586000000001,-0.027895425,0.012009724,-0.032901463,0.00099019,-0.13555731099999999,-0.115561797,1.4284453030000002,2.263872953,-12.04358384,-12.94824781,-13.43204654,-11.51642675,-11.74650212,-10.57469596,-9.936621472999999,-8.871417516000001,-1444.1811519996263 -2771,2771,E169V,0.004141992,-0.044761579,-0.040031474,-0.012339616999999999,-0.136233655,0.260524902,-0.014407304,0.022691287999999997,0.009910995,-0.073964433,-0.015558725,-0.077513412,-0.002549535,-0.041939255,0.017260021,-0.17170775800000002,-0.100759551,1.35170944,2.14145819,-7.9896811329999995,-8.106109734,-10.11983805,-6.062942406,-7.201417801,-8.458097672000001,-5.623025441,-2.403127181,-1437.189363242127 -2772,2772,E169Y,-0.018404298,-0.029936547999999997,-0.038754091000000004,-0.024273212000000002,-0.222237047,0.49526716200000004,-0.01218008,-0.024628516,-0.007669982,-0.04206606,-0.017807036000000002,-0.06210908,-0.015399102,-0.044360729,-0.004185695,-0.252680138,-0.191793955,1.339130369,1.9504885330000001,-8.096605988,-9.803874062,-10.63851283,-5.563165352,-7.780311317000001,-6.697166374,-5.668583919,-3.481176093,-1439.1045562368818 -2773,2773,A170C,-0.052773188,-0.096157354,0.081670243,-0.086413306,-0.09577479800000001,0.067317312,-0.07630397400000001,-0.029242402,0.053093260999999996,-0.143113455,-0.049201253,0.011367608999999999,0.151972877,-0.08411425300000001,-0.088712358,0.018314207,-0.20986380300000002,1.25999479,2.58105472,-10.44077623,-11.38113672,-10.68103928,-10.05096712,-9.979572014,-10.11116599,-8.592889901,-5.866684601,-1451.5580999618396 -2774,2774,A170E,-0.121502463,-0.06307541900000001,0.022378402999999998,-0.047354243,-1.638338553,0.07678194599999999,-0.06287368900000001,-0.180131237,0.010155439,-0.183231358,0.057080520999999995,0.001886748,0.042870057999999996,-0.036413417999999996,-0.058295067,-1.451702721,-1.8249743840000001,0.748324407,1.324960167,-10.31142313,-11.80940947,-9.454102921,-12.95318264,-8.389646324,-8.950774277,-7.93025815,-3.689510933,-1449.2364101805724 -2775,2775,A170D,-0.12075219,-0.116378365,-0.023475747999999998,-0.018752912,-1.2364337859999999,-0.019428551999999998,-0.091515924,-0.149988456,-0.032476619,-0.155673354,-0.077083376,-0.10042847,0.053476975,-0.027146734,-0.010359089,-1.021038868,-1.451828703,0.631843199,1.3449206230000001,-9.92497505,-11.12809231,-8.076365311,-13.81858656,-8.002775932,-8.599055137999999,-7.213962577,-1.9817706069999999,-1448.4674918567762 -2776,2776,A170G,-0.032415071000000004,-0.041782677000000004,0.025310166000000002,-0.02862125,-0.06281982900000001,0.006997078,-0.028266423,-0.036563719,0.005474749,-0.110314043,0.026748689,-0.024201425,0.074821757,-0.035454861000000004,-0.021787637999999998,-0.032359822999999996,-0.093279834,1.408082595,2.556899191,-3.998827403,-5.538603202999999,-3.5171929019999997,-4.806930519,-2.907747635,-3.223662758,-5.236393617,-2.506058528,-1459.7128940108232 -2777,2777,A170F,-0.046228883,-0.038893992,0.019507549,-0.055667898,-0.379657619,0.55958691,-0.018884077,-0.073573689,0.066094737,-0.125837052,0.04804906900000001,-0.067852941,0.106868039,-0.102150365,-0.00918543,-0.28370070199999997,-0.47561453600000003,1.6481118469999998,2.157419978,-12.13811876,-9.776086876,-14.40156111,-12.56584692,-11.49757026,-12.44952863,-6.655469915,-2.9744858780000003,-1441.0100251748227 -2778,2778,A170I,-0.10490715800000001,-0.052635375,0.066169441,-0.031905413,-0.499302942,0.04205438400000001,-0.06675937900000001,-0.143054936,0.003799796,-0.117964626,0.012693877,-0.011143063,0.143481945,-0.021173452000000002,-0.042637374000000006,-0.44777242799999994,-0.550833455,1.260561951,1.709475478,-12.64740321,-12.57925598,-15.80080974,-11.66315922,-11.07511851,-12.11867262,-7.1121191370000005,-3.263873031,-1438.7981162709184 -2779,2779,A170H,-0.065961038,-0.054769974000000006,0.015158224,-0.019989411000000002,-0.422100168,0.7117553879999999,-0.066052494,-0.065869581,-0.011520839,-0.078210163,-0.031329785,0.048119397,-0.01780295,-0.000631242,-0.039347579,-0.17581898899999998,-0.6683813470000001,1.151753969,1.9654993630000002,-11.79096771,-13.9413994,-12.67059221,-12.27446781,-10.16410275,-9.904276375,-8.67328071,-5.14187175,-1452.7630176958628 -2780,2780,A170K,-0.18601348399999998,-0.022392553,0.057503161,-0.066294609,-2.138205066,0.123040496,-0.075433113,-0.296593854,0.022355091,-0.142639708,0.09785460300000001,0.070054324,0.044951998,0.030163916000000002,-0.162753134,-1.6972153890000001,-2.579194743,0.5952033210000001,1.306977082,-10.48569397,-13.70631238,-9.503845558,-11.31636265,-9.653880615,-8.248068626,-7.3730556720000004,-3.62545214,-1450.4290026533417 -2781,2781,A170M,-0.020488045,0.022837259,0.07187471299999999,-0.022317043999999998,-0.6514387079999999,0.222044188,0.03859571,-0.079571799,0.011356541999999999,-0.018424567,0.064099085,0.038650977,0.10509844800000001,-0.012859223000000001,-0.031774865,-0.603793704,-0.6990837120000001,0.597992691,1.393153012,-13.57327263,-14.12124318,-14.90980766,-13.70247703,-12.633886,-12.49894929,-8.75654738,-5.161878933000001,-1445.4256842723116 -2782,2782,A170L,0.006327951,-0.041927394,0.033883849,-0.036705456000000004,-1.003401435,0.10953636,-0.002155978,0.014811878999999998,0.004971412,-0.168503318,0.084648531,-0.068989503,0.13675720000000002,-0.073875734,0.000464823,-0.777766449,-1.229036421,1.264081611,1.5539096909999999,-13.60284708,-13.60104256,-14.91455549,-13.6224366,-13.19736761,-12.67883314,-8.182010365,-4.0588607,-1436.5664472542703 -2783,2783,A170N,-0.13138714199999998,-0.027158272999999997,0.028140192,-0.05820261,-0.31425025,0.010971807,-0.031449642,-0.231324642,0.029082811,-0.078150585,0.02383404,0.0037522859999999996,0.052528097999999995,-0.057276793,-0.059128426,-0.265301317,-0.363199182,1.634631889,2.184577605,-7.9692615589999996,-10.72011871,-8.069554794,-9.798834579,-5.469021004,-5.788778709,-5.317546362,-2.12183132,-1447.2053185557015 -2784,2784,A170Q,0.027145552000000003,0.069486243,0.08438088199999999,0.0016696810000000001,-1.5851603140000001,0.190289371,0.087083616,-0.032792512999999995,-0.008153514,0.022914105,0.116058381,0.050594502,0.118167261,0.030206892000000003,-0.026867531,-0.981989655,-2.1883309719999997,0.670563404,1.3531055440000002,-11.38778377,-13.23523441,-11.02280081,-13.37741454,-9.830391083,-9.473078026,-7.833888245,-2.8089587989999996,-1448.9133375594392 -2785,2785,A170P,0.04309479099999999,0.019750567,0.090874703,0.028561856,-0.502327118,0.693849974,0.024715523,0.061474059000000005,-0.0076101219999999995,-0.058313847,0.09781498,0.034648311,0.147101095,0.026825947000000003,0.030297765,-0.39810587,-0.606548365,0.953934636,1.589823449,-9.760103878999999,-10.21045109,-10.52354304,-9.219587654,-9.673593323,-9.173344292000001,-7.53036986,-4.078761878,-1452.7524744295515 -2786,2786,A170S,-0.012677213,-0.065358794,0.075523593,-0.016748596,-0.010849722,0.041644968,-0.056331584000000004,0.030977157999999998,0.036948743,-0.17409524,0.043377652,-0.037498266,0.188545452,-0.047278939000000006,0.013781748,0.004223780999999999,-0.025923223999999998,1.671448915,3.643209181,-4.338230475,-5.460875327999999,-4.222390488,-4.525577087,-3.6482992860000003,-3.834010185,-5.757351579,-2.488701164,-1448.0803062021732 -2787,2787,A170R,-0.058899272,-0.051966162999999996,0.035635582,-0.008292167,-0.9003797020000001,0.265587234,-0.063934458,-0.053864086,-0.025471855,-0.09787018900000001,-0.0060621369999999996,0.016960384,0.05431078,-0.022699077999999998,0.006114745,-0.5862753,-1.214484103,1.037642219,1.525760407,-9.796182004,-11.34121505,-11.08965739,-10.506607,-7.77803212,-8.265398453,-6.900113656,-2.661912079,-1446.6659211143851 -2788,2788,A170T,0.01888895,-0.067069146,-0.012372215,-0.014465438999999998,-0.7204056740000001,0.301163232,0.010256826,0.027521074,-0.013352518999999998,-0.16176717,0.027628879,-0.129471485,0.104727055,-0.059001412,0.030070535,-0.542671067,-0.89814028,1.342121253,1.7019444430000001,-7.358760268999999,-8.112083878,-9.172879477999999,-7.571365158,-5.765362366000001,-6.172110466,-6.718838396000001,-3.0857404689999997,-1444.6588766942732 -2789,2789,A170W,0.020925604,-0.030874172999999998,0.027723814,0.003772246,-0.21375533100000002,0.40966330799999995,0.014750846000000001,0.027100362000000003,0.005510534,-0.093587555,0.03183921,-0.058755339000000004,0.11420296699999999,-0.069717418,0.07726191,-0.17950503,-0.248005631,1.5915227490000001,2.299623932,-12.549656500000001,-14.727724100000001,-12.0736616,-12.33420898,-12.24720695,-11.36548086,-7.144091575,-3.122589728,-1451.6108485907316 -2790,2790,A170V,-0.053605871,-0.03109561,0.045429724000000005,-0.007219354,-0.22716539,0.212341394,-0.055002762999999996,-0.052208979,0.018472688,-0.12246189699999999,0.060270678,0.028668055,0.062191392000000005,0.016174568,-0.030613275,-0.12414011300000001,-0.330190666,1.470164964,2.335729421,-8.372579536,-9.69791011,-12.21688485,-6.91859272,-6.2843833920000005,-6.74512661,-5.809460225,-1.974498799,-1443.369928383734 -2791,2791,A170Y,-0.09593548,-0.091819408,0.038564451,-0.11199079,-0.15246617199999998,0.5295210370000001,-0.10181850199999999,-0.090052458,-0.037726292,-0.153821349,-0.029817466,-0.01460743,0.09173633199999999,-0.11960313,-0.104378449,-0.10518353400000001,-0.19974881,1.4261765569999998,2.282320266,-12.45360946,-11.17721536,-13.40752909,-12.90599371,-11.55923056,-13.21807857,-7.2931944070000005,-3.900950079,-1443.3537265155464 -2792,2792,I171A,-0.09631298,0.123721611,0.018986278,-0.067352633,0.019637073,0.100967011,-0.064098513,-0.128527446,-0.078600752,0.22959356,0.017849662,0.22386015199999998,-0.185887597,0.086274873,-0.22098013800000002,0.216932608,-0.17765846300000002,0.937099349,3.1712903160000003,-1.6672240719999998,-1.573439697,-2.4989618,-2.111166183,-1.261580521,-0.89097216,-2.8855025810000003,-0.364511606,-1450.6730276830494 -2793,2793,I171C,-0.20220208899999997,0.10063520199999999,-0.018744358,-0.05918535,-0.033828286,0.024588827999999997,-0.138642336,-0.265761841,-0.018179748,0.176359923,0.024910481,0.188550065,-0.22603878,0.160654745,-0.279025445,0.17904032600000003,-0.246696898,1.087665001,3.101080646,-6.634358015,-6.658246017000001,-7.275842529,-6.75342086,-6.480944999999999,-6.00333567,-6.73479882,-4.16694674,-1454.3643151051365 -2794,2794,I171E,-0.039921767999999996,0.154594606,0.04851653,-0.021653235,0.01487968,0.081751542,-0.010234085,-0.069609451,-0.081372888,0.279657579,0.029531632999999998,0.26833736,-0.1713043,0.151801434,-0.195107903,0.262677103,-0.23291774399999998,0.9809544929999999,3.0951721610000003,-3.078656253,-2.830795822,-3.6542754289999997,-3.760824417,-2.9015301669999998,-2.245855431,-3.416629285,-0.8146574659999999,-1452.2630840558559 -2795,2795,I171D,-0.105579122,0.049574337,0.01540961,-0.033377748,-0.095848309,0.099263247,-0.024821131,-0.186337113,-0.083274533,0.225882356,-0.126733682,0.244703077,-0.21388385699999998,0.143456055,-0.21021155,0.107243882,-0.2989405,1.0399613859999999,2.981270359,-5.1252798319999995,-4.120596802,-7.698628677,-5.284847183,-4.243056229,-4.279270271000001,-4.793871306000001,-1.889711446,-1446.8004286396317 -2796,2796,I171G,-0.061039008,0.133327904,0.036276848,-0.028479956,-0.010270764,0.158870544,-0.019094265,-0.10298375,-0.056878736,0.237138602,0.029517206,0.24942474899999997,-0.176871053,0.11493250099999999,-0.171892412,0.219258895,-0.239800423,0.9457758629999999,3.07879746,-4.16947151,-4.3701443410000005,-5.124734833,-4.661456009,-3.891563728,-2.799458641,-4.256685672,-1.9199760819999998,-1439.525979578495 -2797,2797,I171F,-0.126633636,0.213098512,-0.02566361,-0.029540465,0.072452323,0.193212196,-0.035480727999999996,-0.217786543,-0.044191052,0.397135014,0.02906201,0.331382983,-0.38271020200000005,0.22231548199999998,-0.281396411,0.2726206,-0.127715955,1.671448915,3.643209181,-3.434239246,-3.907214386,-2.9650725939999996,-1.8983537519999998,-4.141246384,-4.2593091130000005,-4.545035477,-0.757552022,-1451.7051296876743 -2798,2798,I171H,-0.09518807800000001,0.124239645,0.06992852,-0.062571532,-0.076070341,0.219538667,-0.048235825999999996,-0.142140329,-0.055769241,0.200840369,0.04763892,0.28747749699999997,-0.147620458,0.107418684,-0.232561748,0.23912898100000002,-0.391269663,1.081456891,3.3266342860000004,-4.323939069,-4.828925568,-4.291607933,-3.829623985,-4.3647652589999995,-4.3047725980000004,-4.635746769,-1.914659769,-1450.7362693315372 -2799,2799,I171K,-0.203857835,0.010062871,-0.013814213999999998,-0.111687403,-0.029810137,0.09286495,-0.161154136,-0.246561534,-0.169200286,0.209314676,-0.18918893399999998,0.166661339,-0.194289766,0.051706823,-0.275081628,0.201323187,-0.26094346,1.020937332,3.080219537,-0.974225342,-1.14402272,-2.254477058,-0.829373238,-0.7694204179999999,0.126166725,-2.7672495969999997,-1.027763009,-1462.4715284961276 -2800,2800,I171M,-0.13282428,0.10719356099999999,-0.032061623,-0.169560513,-0.08432525199999999,0.10912950199999999,-0.053226992,-0.212421568,-0.063419473,0.23862893,-0.024241809,0.258832316,-0.322955562,0.045183996,-0.38430502200000005,0.226451651,-0.395102154,1.148701582,3.230137117,-2.64753745,-2.9867262119999998,-3.507819717,-2.473800102,-2.537389671,-1.731951546,-5.024949405,-2.607687399,-1460.775251716841 -2801,2801,I171L,-0.053029779000000006,0.168472901,0.059931007,-0.027830146,0.009850653000000001,0.029297893,-0.012498256999999999,-0.093561301,-0.055530389000000006,0.282488665,0.054457137,0.288892415,-0.16903040100000002,0.134323106,-0.189983398,0.281113008,-0.26141170199999997,0.8597312840000001,3.121536077,1.0263578000000002,0.287215218,1.2787992479999999,2.031100266,0.647093887,0.887580383,0.08859719699999999,0.199035965,-1458.7725675981492 -2802,2802,I171N,-0.117746345,0.10418231900000001,0.035746762,-0.047183872,-0.006277549,0.135208309,-0.065961348,-0.169531342,-0.152261864,0.217230785,-0.008866148,0.21408598899999998,-0.142592466,0.13281458599999998,-0.22718233,0.22581787600000003,-0.23837297300000002,0.938734757,3.1088297110000003,-4.245105354,-3.8611394039999998,-4.668823608,-4.565625839,-4.267959625,-3.8619782939999996,-4.362628681,-2.489208616,-1452.6502590971068 -2803,2803,I171Q,-0.136780133,0.15140254,0.051563801,-0.045629091,-0.016285197,0.079487315,-0.100173568,-0.173386698,-0.021028894,0.319744676,-0.016939597,0.312133043,-0.20900544100000001,0.17027892600000002,-0.261537108,0.261245422,-0.293815815,1.543610422,3.106887046,-3.177733354,-2.9495476380000003,-4.291876266,-3.722390068,-2.456833984,-2.468018814,-3.879974675,-1.38447674,-1455.3459061444737 -2804,2804,I171P,-0.050206258,0.1580078,0.08654697900000001,-0.032749403999999996,-0.622117062,0.385792779,0.005079394,-0.10549191,-0.055715550999999995,0.256918148,0.059097450999999995,0.267297332,-0.094203374,0.092493311,-0.15799211900000001,-0.25651028800000003,-0.9877238359999999,0.8795694629999999,1.7084101580000002,-4.046796228,-4.3757248230000005,-6.01796096,-4.0153571239999994,-3.6621448439999997,-2.1627933880000003,-4.828722397,-0.660251418,-1453.4557862374932 -2805,2805,I171S,-0.066464517,0.09545875599999999,0.020383314,-0.030746639,0.007955541,0.161989052,-0.016627085,-0.116301948,-0.056002404000000006,0.222523897,-0.031606385,0.24523530100000002,-0.204468674,0.068267565,-0.12976084300000001,0.1495418,-0.133630718,1.046618325,3.208839672,-3.0940859360000004,-3.052564186,-3.742313171,-3.4594869,-3.0558786469999997,-2.160186775,-3.058052722,-1.143411892,-1451.904248978477 -2806,2806,I171R,-0.088703603,0.118916887,0.041168408999999996,-0.026153707,0.007069098,0.071385272,-0.061478599,-0.11592860599999999,-0.033245416,0.235205655,0.002628118,0.254470718,-0.1721339,0.138340256,-0.19064767,0.244125896,-0.22998770100000002,0.9534124959999999,3.162273815,-1.4678639180000002,-1.367263748,-2.3968422240000002,-2.139248489,-1.013394325,-0.422570801,-2.735783614,-0.522473437,-1456.3829604224302 -2807,2807,I171T,-0.02400513,0.180240328,0.082866377,-0.020739307,-0.012082141000000001,0.171668552,0.041556092,-0.08956635199999999,-0.023871762,0.295898377,0.06458227799999999,0.305764256,-0.140031502,0.12879652,-0.170275134,0.268413272,-0.292577553,0.926636351,3.060451591,-0.5732387179999999,0.500868126,-1.8677338030000001,-1.8347046130000002,0.077572639,0.257804062,-2.07455144,-0.45702996799999995,-1457.603201918304 -2808,2808,I171W,-0.025844596,0.140569231,0.054273255,-0.007553621999999999,0.011755136000000001,0.097088625,0.026553676000000002,-0.07824286700000001,-0.024969222000000003,0.23647427899999998,0.044664182999999996,0.256343515,-0.147797006,0.12113960300000001,-0.136246847,0.21227354399999998,-0.18876327199999998,1.671448915,3.643209181,-6.475497278,-6.831224152000001,-7.058029472,-5.848274979,-6.127106827,-6.51285096,-5.753042872000001,-0.620947563,-1453.0268352851272 -2809,2809,I171V,-0.119862614,0.11045665699999999,0.022800402999999997,-0.042349437000000004,-0.011763923999999999,0.08276876799999999,-0.056777793,-0.182947435,-0.07504464400000001,0.211230685,0.009682628,0.267117468,-0.221516663,0.12038860900000001,-0.205087482,0.21212398899999999,-0.235651836,0.997357017,3.08446084,-1.184860056,-1.0651610409999999,-1.460971931,-1.950264725,-0.898380905,-0.549521675,-2.7009712880000003,-0.430870839,-1459.425484948326 -2810,2810,I171Y,-0.13774284,0.11234123900000001,0.019757903,0.006720588,0.049878287,0.139107693,-0.08853253800000001,-0.186953142,-0.016730053999999998,0.255627176,-0.030944698,0.26345251399999997,-0.223936708,0.21758382199999998,-0.20414264699999998,0.35755154899999997,-0.257794975,1.014288975,3.3338518930000003,-5.022214557,-5.769217133,-3.248272949,-4.71504686,-5.598350494,-5.780185349,-5.131600893,-0.170870913,-1455.141522735823 -2811,2811,P172A,0.001117875,0.002953297,-0.006095496999999999,0.022475883,-0.054554334,0.040140858,-0.0054887009999999995,0.00772445,0.019277943,0.015655931,-0.009749337,0.005751358000000001,-0.017942351000000002,0.044389895,0.000561871,-0.044741645,-0.064367023,1.231996208,2.442412546,-4.184918288,-4.363418381000001,-4.8424460830000005,-4.257608513,-3.4990720439999996,-3.962046417,-6.062814759,-1.7377040730000002,-1461.7211307897232 -2812,2812,P172C,-0.07696613299999999,-0.040921808,-0.010724445,-0.035253481,-0.232375688,0.033277222999999995,-0.076007113,-0.077925153,0.08426145300000001,0.002409814,-0.084253429,0.038859607000000004,-0.060308497,-0.008915731,-0.06159123,-0.122154394,-0.342596981,1.330674272,2.241012084,-10.34097992,-10.69435436,-11.749934800000002,-10.67926831,-9.390919685,-9.190422462,-11.019847300000002,-8.034165643,-1456.2687733718194 -2813,2813,P172E,0.001968066,0.001442035,-0.022126802,0.02185824,0.013131383,0.047142548,-0.009442131999999999,0.013378263999999999,0.011018408,0.030556952000000002,-0.027672883,-0.025078303,-0.0191753,0.038753824,0.004962655,-0.014126159,0.040388924,1.5464736069999998,2.938183126,-5.779987203999999,-6.171462502000001,-6.462473152,-6.00425502,-5.002051796,-5.25969355,-6.166718781,-1.4663134709999999,-1461.9041110565886 -2814,2814,P172D,0.0019527070000000001,-0.082176293,-0.06239503,-0.068523337,-0.162923428,0.103830401,0.007719485,-0.0038140709999999996,0.006812686,-0.065372523,-0.098980062,-0.05650614599999999,-0.068283913,-0.072608718,-0.06443795599999999,-0.08508599,-0.240760865,1.3550698,2.3000461480000003,-6.691720938,-5.931287666,-8.411797234,-6.470429413,-6.4959942470000005,-6.14909613,-5.814514602999999,-1.030554757,-1464.0262627438642 -2815,2815,P172G,0.011769867,-0.020191912,-0.01692597,-0.023617415,-0.29261040000000005,0.19001301,0.01312699,0.010412743,0.024247391,-0.019344609,-0.021039214,-0.028432613,-0.0054193259999999995,-0.019351301,-0.027883529,-0.230312333,-0.35490846600000003,1.658533535,2.263259212,-7.077279787999999,-7.402169594,-8.359193871,-7.290476418,-6.119342833999999,-6.215216225,-7.521392221,-3.313578728,-1459.528579828795 -2816,2816,P172F,-0.019773916000000002,-0.004722398,-0.021259545,-0.018058491,-0.209981855,0.035778912999999996,-0.036455581,-0.00309225,-0.017661083,-0.015004597,0.005559801,-0.002258296,-0.040260792999999996,-0.010472129,-0.025644852000000003,-0.169047753,-0.25091595699999997,1.544516459,2.29839057,-10.26263951,-10.68089321,-12.48024335,-10.90829728,-8.520697418,-8.723066292,-9.198343392,-6.156125901,-1452.675544262398 -2817,2817,P172I,-0.107478003,-0.109593588,-0.155593595,-0.102566746,-0.179605393,0.018884004,-0.104544741,-0.110411265,0.007633354,-0.075410433,-0.14377674199999999,-0.09229746900000001,-0.218889721,-0.08910832199999999,-0.116025169,-0.182890534,-0.17632025199999998,1.5665437830000002,2.239060652,-6.840779039,-7.644942154,-7.6711853560000005,-7.601037819,-5.123333809,-6.163396057000001,-7.012814838,-3.997347323,-1452.8294388833456 -2818,2818,P172H,0.078248106,0.005676646,-0.0030090140000000004,0.060013897999999996,-0.099280105,0.037115569,0.08689524,0.069600972,0.045825175,-0.039116498,0.05046979,-0.029967285,0.023949257,0.000982995,0.11904480099999999,-0.146234959,-0.05232525,1.233807273,2.081520001,-7.895547705,-8.447533768,-10.313887699999999,-7.395786018,-7.007332916,-6.313198128,-7.452325407999999,-3.656322212,-1463.723836499732 -2819,2819,P172K,-0.069295913,-0.02546872,-0.012185338,-0.02600526,-0.150293483,0.061738815999999995,-0.061533097,-0.07705872799999999,0.037856245,0.039312171,-0.09024961,0.017291669,-0.041662345,0.002003096,-0.05401361599999999,-0.063209806,-0.23737715899999998,1.3065021479999999,2.41036893,-4.889110747,-6.0849689410000005,-4.254709175,-6.044946982999999,-4.3294653169999995,-3.7314633180000003,-6.606969952,-1.797037565,-1460.0361777511425 -2820,2820,P172M,0.016380443999999997,0.006183593,0.027069726000000002,0.005683074000000001,-0.063852169,0.041613358999999996,0.019783055,0.012977833000000001,0.08472526699999999,0.021510195,-0.009143009,0.012887692,0.04125176,0.01167293,-0.000306782,-0.11317641099999999,-0.014527926000000002,1.325568531,2.276970377,-7.30287317,-8.204166183,-8.82109285,-8.740728683,-5.507420311000001,-5.240957825,-7.46083837,-4.123267578,-1458.2212039846927 -2821,2821,P172L,-0.013239043,-0.012600623,-0.008347555999999999,0.013031208,-0.088987201,0.045285132,-0.016003924,-0.010474161999999999,-0.008864002,0.015493691,-0.040694936,0.009441395,-0.026136506,0.04392932099999999,-0.017866905,-0.06366941,-0.114304992,1.3247381040000001,2.446562814,-5.328741733999999,-5.797363373,-6.869375175,-6.456270546,-3.9210318369999997,-3.59966774,-5.530288904,-2.202995031,-1458.0271905194968 -2822,2822,P172N,-0.022093703,0.031018935,-0.006068476,-0.023893327000000002,-0.170574423,0.136605588,-0.005995673000000001,-0.038191733,0.026153252000000002,0.013900105,0.048137764000000006,0.041208662,-0.053345613,-0.037186115,-0.010600538,-0.192735469,-0.14841337599999999,1.276463678,1.982014116,-7.211386871,-7.369155075,-8.078953957000001,-8.234123947,-6.789147095,-5.585554283,-7.9983154910000005,-2.695125687,-1466.401544587221 -2823,2823,P172Q,0.018725474,0.003644287,-0.039118791,-0.045657909,-0.06438121599999999,0.007023506999999999,-0.036191491,0.073642439,0.03482979,-0.008019714,0.015308287,-0.057433949000000005,-0.020803633000000002,-0.07875695099999999,-0.012558866,-0.079353946,-0.049408485999999995,1.380362695,2.33842162,-5.748854113999999,-6.811698448,-6.159942566000001,-5.824483391,-4.792270454,-5.15587571,-6.688081261000001,-2.453653873,-1460.4052109643817 -2824,2824,P172S,-0.011998831000000001,-0.020994856,-0.031657725,-0.029486734,-0.142501876,0.04294368,-0.037138929,0.013141268000000001,-0.001029218,-0.043079157,0.001089446,-0.046502500999999995,-0.016812949,-0.018540195,-0.040433273,-0.137355525,-0.147648226,1.318005127,2.1425803969999997,-5.426282378,-5.737481026,-5.927299522,-6.0058177189999995,-4.714068672,-4.746744949,-6.542918154,-2.677748152,-1462.1889968360774 -2825,2825,P172R,-0.032054837,-0.032427656,-0.032357698,-0.028632402,-0.19472374899999997,0.097271059,-0.026794883,-0.037314791,-0.009618363000000001,-0.021264424,-0.043590887,-0.049636055,-0.01507934,-0.03352142,-0.023743383,-0.153306189,-0.236141308,1.5383968190000001,2.305254609,-5.98171881,-6.366349266,-8.162817741,-5.58078141,-5.054556938,-4.744088692,-6.929385623,-2.19294624,-1465.7541961930692 -2826,2826,P172T,-0.034828631,0.018208693999999997,-0.019928028,-0.018340461000000002,-0.091111296,0.07525266,-0.029939896,-0.039717366000000004,0.035008402,0.006623466,0.029793922,-0.019088669,-0.020767386000000002,-0.004696119,-0.031984803,-0.10470023699999999,-0.077522355,1.375364729,2.330075134,-5.941827704,-5.975063469,-6.9239668960000005,-6.212816642999999,-4.976660202,-5.62063131,-6.708227152999999,-3.1508456739999997,-1460.9511019587517 -2827,2827,P172W,0.002994454,-0.006930095,-0.021457196,-0.013916623000000001,-0.276195727,-0.000691368,0.006030806999999999,-4.1899999999999995e-05,-0.025062097999999998,0.019369773,-0.033229962,0.0023011729999999997,-0.045215565,-0.003084136,-0.02474911,-0.207077048,-0.345314406,1.33877029,2.082277416,-10.16215466,-10.48194019,-12.54818049,-10.31205666,-8.907524437000001,-8.561071502999999,-9.458007638,-5.9335892999999995,-1456.6174136539921 -2828,2828,P172V,-0.029239919,-0.008407592,-0.004568361,-0.028244098999999998,-0.09745996900000001,0.043234017,-0.033917556,-0.024562281000000002,0.03931267,-0.00798717,-0.008828014,-0.003608428,-0.0055282940000000004,0.012968047,-0.069456244,-0.071663629,-0.12325630800000001,1.20163706,2.221100871,-6.088387537999999,-7.051690605,-6.695140991000001,-6.544233352999999,-4.257088974,-5.893783768,-7.076851192,-3.1396178989999997,-1453.2559296074323 -2829,2829,P172Y,-0.026845326,-0.042793402,-0.025758065,-0.042041594,-0.19954440899999998,0.068970135,-0.017117611,-0.036573041,0.067677013,0.003911404,-0.089498207,0.017136231000000002,-0.06865236,-0.035796611,-0.048286577000000004,-0.18737374,-0.211715078,1.45179385,2.174120846,-8.503719482000001,-8.822316795,-11.73148089,-8.593373238,-6.683565475,-6.687861015,-7.368743381,-2.546249666,-1454.1839432045817 -2830,2830,N173A,0.006717756,0.037353923,0.015937926,0.004064735999999999,0.013932702,0.030829309,0.053005352,-0.03956984,0.015424618000000001,0.057293893,0.017413953,-0.047528339,0.07940419,0.000709052,0.007420419,-0.029112952,0.056978355,1.349032761,2.537183893,-1.5775492480000002,-1.936636597,-1.78372702,-1.173321899,-1.6168311919999998,-1.37722953,-2.61833548,0.954854938,-1463.4993942668661 -2831,2831,N173C,0.0014393960000000001,-0.021186905,0.005098947,0.00135119,-0.014365243,-0.032295283,-0.00448532,0.007364112,-0.032948717,0.018375827,-0.060749635999999996,-0.035893272000000004,0.046091165999999996,-0.030368917000000002,0.033071297,-0.053451128,0.024720642999999997,1.308310082,2.407821952,-5.8069044860000005,-5.884991966,-6.572581047000001,-5.845441872,-6.343238541,-4.388269005,-6.669226787,-3.839370534,-1462.3369939280674 -2832,2832,N173E,0.007260559000000001,-0.005198744,-0.024207679,-0.009863304,-0.008709017,-0.0036405,-0.006385892,0.020907009,0.016133178,-0.047982624,0.037585136,-0.073467091,0.025051734,-0.034399282999999996,0.014672676,-0.043144978,0.025726945,1.4145505619999998,2.455773264,-2.33825419,-2.512686981,-1.576178078,-2.488184563,-3.47100676,-1.643214569,-4.272080084,-0.380742051,-1461.2488908255473 -2833,2833,N173D,-0.028956548,-0.0071130080000000005,-0.018001773000000002,0.001731535,-0.029921061000000002,-0.032295685,-0.057270647,-0.000642448,0.044087815,-0.002374712,-0.011851303999999998,-0.01524408,-0.020759465,0.029530732,-0.026067662000000002,-0.015468124,-0.044373997000000005,1.216995399,2.621633422,0.32512818600000004,0.77216433,-0.244569008,0.339980331,0.161853111,0.596212166,-2.139559444,0.274190508,-1459.5851954934187 -2834,2834,N173G,0.009624825,-0.013039997,-0.00323681,-0.002602129,-0.0016216610000000002,-0.053431259,-0.010171811,0.02942146,0.029019918999999998,-0.021075361,-0.005004632,-0.035354312,0.028880692000000003,-0.019126617,0.01392236,-0.021595327,0.018352005,1.345368132,2.5498268790000003,3.4320917019999997,3.834842751,3.61705571,2.9999963760000004,3.0847158130000003,3.623847862,0.062596968,2.16086604,-1468.9834189708345 -2835,2835,N173F,-0.065032233,-0.044671398,-0.018176517,-0.058276960999999995,-0.024432157000000003,0.018264583,-0.052821078,-0.077243388,0.082362744,0.024836834,-0.114179629,-0.008987913,-0.027365121000000003,0.00209299,-0.118646912,0.018915325,-0.067779638,1.138968955,2.6583521969999997,-5.21633231,-7.600942291,-5.173079926000001,-4.812976128,-4.361176155,-4.1334870530000005,-5.189178868,-2.519573181,-1460.6391938864253 -2836,2836,N173I,0.023717112999999998,-0.005189174,-0.022162865,0.014634442,-0.31411793600000004,0.072175004,0.048504119000000005,-0.0010698939999999998,-0.048154616,-0.05589482,0.045516472,-0.030282081000000002,-0.014043648,-0.003842791,0.033111674,-0.29894287199999997,-0.329292999,1.5646825480000002,2.074081493,-5.158388396,-4.04605407,-4.706553116,-6.16615654,-6.462567635,-4.410610619,-5.188377326,-0.532361682,-1458.9102141740732 -2837,2837,N173H,-0.018152499,0.029554828,-0.005303441,-0.015475341,0.002965655,0.01376499,-0.033212343,-0.0030926540000000002,-0.016413853,0.104642955,-0.045533299000000006,0.0028223470000000002,-0.013429228,0.010117134,-0.041067815,0.011759904,-0.005828594,1.166459095,2.648404694,-2.9541436689999996,-3.857161118,-2.817829872,-2.5371143259999998,-2.549466133,-3.0091468960000003,-3.956380424,-1.7013822809999999,-1465.947656149976 -2838,2838,N173K,-0.012951778999999998,-0.031149081000000002,0.008291035,0.008988504,-0.014792412,-0.023180697000000004,-0.005920991,-0.019982566,0.010473745999999999,-0.00499769,-0.057300471,-0.002366,0.01894807,0.019428551999999998,-0.001451544,0.008688904,-0.038273727,1.264115617,2.776666739,-1.143728734,-0.40531778700000004,-0.278602463,-0.999094185,-2.46672744,-1.568901794,-2.3649620209999997,0.400786939,-1465.5888843508437 -2839,2839,N173M,-0.030488914,-0.016288733,-0.000592062,-0.006250774000000001,-0.054697623,0.002449613,-0.016958651,-0.044019177,-0.030854841,-0.002291797,-0.030285667999999998,0.0035439559999999996,-0.00472808,-0.030949136000000002,0.018447588,-0.066137294,-0.043257950999999996,1.213159661,2.2732302030000002,-6.629217696,-6.079475112999999,-5.8601058429999995,-7.631908051,-7.460525597,-6.114073875,-5.477377975,-2.250224297,-1462.5370271122083 -2840,2840,N173L,-0.015126918999999999,-0.009105936,-0.022944468,-0.018635164,-0.030604266,-0.016878739,-0.009211185,-0.021042652000000002,0.017450101000000003,0.018084547,-0.036296418,-0.047634787000000005,0.0017458520000000002,-0.02408399,-0.013186338,-0.037431812,-0.023776718999999998,1.20233237,2.401994425,-4.301497604,-3.627875008,-4.1051952819999995,-5.2760477219999995,-5.534057434,-2.964312576,-3.58166368,-0.28901689399999997,-1455.9356536553241 -2841,2841,N173Q,-0.031887827,-0.008382269,-0.007088817,0.0007295930000000001,0.023715873999999998,0.029596575,-0.043756562,-0.020019092,0.03804839,0.035858024,-0.052622561,0.010584621,-0.024762253999999997,-0.013481101,0.014940287,-0.01873685,0.066168597,1.207256321,2.5167904119999998,-3.6310231839999996,-4.1630152439999994,-2.365865685,-3.909438522,-4.804236595,-2.912559875,-4.385818965,-0.22830900899999998,-1467.562358383555 -2842,2842,N173P,-0.02212302,-0.001234391,0.009059293000000001,0.0027470109999999997,-1.7161871430000002,0.49544348299999996,-0.010301439,-0.0339446,-0.004613963,0.003117178,-0.005585959000000001,-0.048739033,0.06685761900000001,-0.012387493999999999,0.017881516,-1.497526418,-1.9348478669999998,0.66379259,1.319291736,-4.4959891569999995,-4.750328377,-5.165717453,-4.331642296,-5.2471920469999995,-2.985065613,-4.6554476639999995,0.552280031,-1459.0709898853675 -2843,2843,N173S,0.01982762,0.011568057,0.023774447,0.019108757,-0.000747788,-0.01700364,-0.003428385,0.043083625,0.016498936999999998,0.017113987,0.0060221269999999995,-0.013227043,0.060775937,0.001522205,0.036695309,-0.043010846,0.041515271,1.414904449,2.54082215,-1.184478726,-1.098721489,-1.419968216,-1.6590315930000001,-0.610461227,-1.134211105,-2.921137481,-0.405690245,-1458.4355975585058 -2844,2844,N173R,0.019599032,0.021942557,0.024035294,-0.015800575,-0.050087137000000004,-0.012407962,0.023468021000000002,0.015730043,-0.002347408,0.023770677999999996,0.020114436,-0.014398598,0.062469185999999996,-0.02023669,-0.01136446,-0.095554241,-0.004620033,1.206623067,2.244273076,-3.525812575,-3.74708847,-2.801318329,-3.694113075,-4.8580986710000005,-2.528444328,-3.807194379,0.23209979100000003,-1466.2998829018325 -2845,2845,N173T,0.015469235,-0.006757010999999999,-0.010485862,-0.005613795,-0.027061775,-0.039670235,0.008124669000000001,0.022813801,0.017541461,0.018315236999999998,-0.031829258,-0.03524985,0.014278126,-0.039189443,0.027961853999999998,-0.079821878,0.025698328,1.276815348,2.2728484669999998,-2.079378719,-0.92025946,-2.566160385,-2.666741058,-2.447819695,-1.795912994,-3.3247067930000003,-0.555265434,-1461.6467889766209 -2846,2846,N173W,0.026021317000000002,0.032000252,0.020948564,0.022435255,-0.004127451,-0.015243713999999998,0.032901101,0.019141533,-0.02724949,0.038733973,0.025266531000000002,0.015829975,0.026067153,-0.009690456,0.054560965,-0.021424036,0.013169133999999999,1.2387622759999999,2.562574386,-4.591917596,-5.531064194,-4.987632431000001,-3.976604988,-5.3799477079999996,-3.0843386610000003,-4.454155663,-0.9880047270000001,-1460.4367696079426 -2847,2847,N173V,-0.008661536,0.004203941,0.022232166,-0.005998165,-0.25577747100000003,0.026388557000000003,-0.018732144,0.0014090729999999998,-0.014895101000000001,-0.005189509,0.013597391,-0.027048137000000003,0.071512468,-0.036358243,0.024361913,-0.26460916100000004,-0.24694578,1.5305716569999999,2.001357715,-3.915617957,-1.373306343,-3.52046376,-4.880979568,-5.799297646,-4.004042465,-3.9730262960000005,0.22084219300000002,-1459.1734740277752 -2848,2848,N173Y,-0.079363867,0.025983352999999997,0.022069182000000003,-0.002515225,0.017112284,0.015775837,-0.022957961000000002,-0.135769773,0.014858208999999999,0.065495825,-0.01352912,0.041286847,0.0028515159999999997,0.028284642999999998,-0.033315092000000004,-0.010042843000000001,0.04426741,1.153400526,2.75274485,-4.031157385,-5.249492523,-4.06450106,-3.6599555510000004,-3.4281777730000003,-3.753660019,-4.713525265,-1.538049508,-1460.4780052169226 -2849,2849,D174A,-0.052629167000000004,0.003324744,-0.019212198,-0.75887084,-2.121400628,0.007686256,0.018223813000000002,-0.12348214699999999,-0.058473328,-0.00196796,0.008617447,-0.045184178,0.006759782,-0.507834937,-1.009906742,-2.097991022,-2.144810234,1.6382496469999999,1.353995745,-10.72180954,-11.98618529,-11.0874538,-10.10832262,-9.611200455,-10.81588554,-6.749222704,-2.044681056,-1457.457867931109 -2850,2850,D174C,-0.14487539,0.031707962,-0.048474830999999996,-0.012351426,-1.4579015780000002,0.024806731000000002,-0.126147839,-0.16360294,-0.038815783,0.091345199,-0.027929276,-0.059874285,-0.037075376,-0.00651857,-0.018184281,-1.621256896,-1.294546259,0.624152881,1.311173159,-15.31797137,-16.90184961,-16.13804378,-13.63742892,-14.49939695,-15.41313757,-8.898604022,-3.6533692460000005,-1459.4865380683914 -2851,2851,D174E,-0.042995964000000005,0.05843266,-0.017634674,-0.006814221,-0.7127737590000001,0.109284701,-0.00042987900000000004,-0.085562048,-0.032331413999999996,0.083670847,0.033194472999999995,-0.027934529,-0.007334818000000001,-0.010541958999999998,-0.0030864829999999997,-0.575847137,-0.8497003809999999,0.860021519,1.458078294,-6.850690947,-8.231850166000001,-8.379272308,-5.904459877000001,-5.553889221,-6.1839831620000005,-5.93359849,-1.817969274,-1458.3818089431152 -2852,2852,D174G,-0.05122339,0.028650339,0.0021016439999999997,-0.190435789,-1.960745279,0.008787521,0.0014168579999999998,-0.103863637,-0.04753417099999999,0.037825601,0.019475077,-0.009307786,0.013511074,-0.11285525800000001,-0.268016319,-1.6843353680000002,-2.23715519,0.9283353940000001,1.32552305,-10.734598599999998,-11.72497608,-13.26781647,-11.3823937,-8.288051575,-9.009755188,-5.957762258,-0.788055044,-1455.3344163140282 -2853,2853,D174F,-0.121080189,0.002685033,-0.510628104,-1.781082166,-2.8999826619999998,0.005956688000000001,-0.09031271699999999,-0.151847661,-0.070098088,0.059261540999999994,-0.053891475,-0.27968969,-0.741566518,-1.6885491259999998,-1.873615205,-2.574595567,-3.225369756,1.3232390170000001,0.749759396,-17.31291887,-18.41995615,-20.33129092,-14.99844891,-13.599502300000001,-19.21539608,-8.260778515,-3.916737587,-1457.2253676098771 -2854,2854,D174I,-0.060031985999999996,0.04373365,-0.042478710999999995,-1.767508024,-2.5516905569999997,0.076786745,0.023200632000000002,-0.14326460300000002,-0.057860583,0.0431468,0.044320499000000006,-0.067198841,-0.01775858,-1.51627307,-2.018742978,-2.377495927,-2.725885187,0.7886836979999999,0.7087084570000001,-14.82132415,-16.29657623,-17.45395241,-13.54354298,-12.28734844,-14.52520071,-8.602615199999999,-4.962971945,-1462.3815081710927 -2855,2855,D174H,-0.008465674,0.035613992000000004,0.029013143999999998,-1.4936656209999999,-2.623160767,0.025922514,-0.014194878000000001,-0.00273647,-0.059021507,0.029850462,0.041377521,-0.024571614,0.082597901,-1.205178922,-1.78215232,-2.334263412,-2.912058122,1.024948377,0.7740566059999999,-13.42042128,-15.116016199999999,-14.30366535,-13.77900986,-10.4713991,-13.43201588,-8.940356751,-4.78260309,-1451.9144091242924 -2856,2856,D174K,-0.11881668,0.042919612999999995,-0.393902232,-1.886997904,-2.962412655,0.048693848,-0.040677891,-0.196955468,-0.081535836,0.07299053,0.012848695,-0.198611228,-0.5891932360000001,-1.528753655,-2.245242153,-2.389976512,-3.534848797,1.204553149,0.756009348,-12.08782319,-12.85727001,-14.922868300000001,-12.20642,-10.30637704,-10.14618062,-7.740219294,-3.7693246069999997,-1448.6931644598953 -2857,2857,D174M,-0.10060737,0.009207077,-0.023731243,-1.3248412509999998,-2.8421316689999996,-0.008027923000000001,-0.052720333,-0.148494407,-0.021529929,0.016310466000000003,0.002103688,-0.050189852,0.002727367,-0.8716322740000001,-1.7780502280000001,-2.451796216,-3.232467122,1.017395755,0.836546245,-14.63039694,-14.82352807,-17.30967104,-13.18460075,-11.62433072,-16.20985413,-8.139779653,-4.486792331,-1456.582895860076 -2858,2858,D174L,-0.06593769599999999,0.034121741000000004,-0.002635099,-1.798651445,-2.590402136,0.023881523999999998,-0.030506029,-0.101369363,-0.054496544,0.062456752000000004,0.005786729,0.013274433,-0.018544631000000002,-1.494513623,-2.102789266,-2.322568117,-2.858236155,-0.020622953,0.683024565,-13.40808023,-14.27438631,-17.23506212,-12.21390413,-8.933121086,-14.38392751,-7.79682329,-3.317974661,-1456.5486448332667 -2859,2859,D174N,-0.12302409,0.006339142,-0.038943864,-0.054175147,-2.324862848,0.043555288,-0.026408582000000003,-0.21963959800000002,-0.101102369,0.036782956,-0.024104672,-0.03869449,-0.039193238,-0.053868313,-0.054481981,-1.911499819,-2.738225877,0.8857948309999999,1.307908979,-8.112277916,-9.358982574,-7.574041458,-7.766176125,-8.592784568999999,-7.269404853999999,-6.23158537,-3.1152999930000003,-1450.9951607333496 -2860,2860,D174Q,0.001966151,0.053777371,0.012006858,-0.011301994,-2.490967543,0.034189321,-0.014093236,0.018025538,-0.077660242,0.08744518400000001,0.020109557,0.007728953,0.016284763,0.005846175,-0.028450162,-1.7576675990000001,-3.2242674860000005,0.473835437,1.30135375,-12.04189703,-15.05711369,-12.87870181,-11.01854622,-10.33882002,-10.91630344,-6.812272248999999,-1.7762256090000001,-1452.865916213952 -2861,2861,D174P,-0.03251293,0.024434311,-1.108504614,-2.094969647,-3.314416907,0.060837423,0.031681674,-0.09670753300000001,-0.060850844,0.024807843,0.024060777999999998,-1.0025577970000001,-1.2144514309999999,-2.098431038,-2.091508256,-2.770597659,-3.858236155,0.692873078,0.11777025199999999,-13.79912807,-16.70872829,-14.41170055,-13.1364435,-11.00756654,-13.73120151,-7.3574719129999995,-3.59882789,-1457.7718442920595 -2862,2862,D174S,-0.08567733300000001,0.035044848999999996,-0.015640083,0.00855648,-1.527444944,0.104100545,-0.045088948,-0.126265717,-0.042696326,0.045241312,0.024848385,-0.012585198999999998,-0.018694967,0.015323951,0.001789009,-1.558584613,-1.496305274,0.6997556159999999,1.3183804909999999,-11.29878411,-13.99638942,-11.124955300000002,-10.46778622,-11.21910447,-9.685685127000001,-6.383975679,-2.304830747,-1454.621984736994 -2863,2863,D174R,-0.028739273,0.030905215,-0.673220278,-1.900896381,-3.00426622,0.010353586,0.01353992,-0.071018465,-0.048604733,0.032033419,0.02977701,-0.42173279,-0.924707765,-1.802810526,-1.998982235,-2.413381076,-3.595151364,1.61656737,0.789696553,-12.95140664,-14.89354681,-15.53130252,-14.29268494,-9.473947357,-10.56555155,-7.097927007000001,-2.39717509,-1448.845850305166 -2864,2864,D174T,-0.085681779,0.023085966,0.006709983,-0.602217559,-2.4560801740000002,0.040680047000000004,-0.013226696999999999,-0.15813686,-0.044922271,0.049807909000000004,-0.0036359779999999998,-0.029384902999999997,0.042804869,-0.284968071,-0.919467046,-1.8750219559999999,-3.037138391,1.351548306,1.346736471,-11.61514034,-13.79932217,-13.16772493,-10.32089631,-9.042235359,-11.745522900000001,-6.516578542,-2.429377386,-1457.5506505970843 -2865,2865,D174W,-0.065688432,0.003438618,-0.829227068,-2.085911512,-3.101784767,0.013990912,-0.034423651,-0.09695321300000001,0.004511703,-0.0038941040000000002,0.010771339,-0.527036315,-1.1314178209999999,-1.8555849999999998,-2.316238024,-2.507548234,-3.696021299,1.703817929,0.795774579,-16.33919035,-18.16587011,-17.91834765,-15.34762374,-13.49255187,-16.77155839,-9.16027713,-5.570763137,-1456.572934891563 -2866,2866,D174V,-0.10716180800000001,0.002036564,-0.036421864,-1.473654375,-2.7174936080000003,0.019101382,-0.041259022,-0.173064594,-0.053902593,0.014525455,-0.010452328,-0.026921307000000002,-0.04592242,-1.007927867,-1.939380883,-2.31994304,-3.115044175,0.823624515,0.7717848690000001,-14.06362061,-15.68441897,-16.11815984,-12.93904907,-11.38807688,-14.18839827,-8.271656587,-4.240862203,-1458.0903253392316 -2867,2867,D174Y,-0.109499537,-0.005627213000000001,-0.296041971,-2.311744967,-2.7255582310000004,0.028563421000000002,-0.028472921,-0.190526152,-0.050086654,-0.003662603,-0.007591822,-0.152966273,-0.43911766799999996,-1.933356197,-2.6901337360000004,-2.284289437,-3.166827024,1.122447296,0.686400881,-16.93467668,-18.80760307,-20.257714399999998,-14.70762085,-13.47006979,-17.43037528,-8.835744072,-2.590810884,-1456.633101775311 -2868,2868,E175A,-0.023573853,-0.016242182,0.020863976,0.025225471,-0.050278435999999996,0.041145537,-0.077638868,0.030491162999999998,0.043845836,0.005261324,-0.037745688,-0.005516729000000001,0.047244681,0.02871346,0.021737481,-0.041828979,-0.058727892000000004,1.3125776759999999,2.553003902,-2.408082179,-2.17261647,-2.252398941,-2.175702911,-3.133446915,-2.306245659,-3.2611604339999998,-1.191461162,-1464.5805652705021 -2869,2869,E175C,0.013717798,-0.014984208,-0.030447693999999997,-0.019242896000000002,-0.115690451,0.075216558,-0.00033293699999999995,0.027768532999999998,0.061553884,0.0009541780000000001,-0.030922593999999998,-0.058915536,-0.0019798520000000003,0.00798784,-0.046473630999999994,-0.070737669,-0.160643232,1.24745667,2.3568389830000003,-7.926379904,-7.830895592,-7.026179115,-8.544173714,-8.847645424,-7.383005676,-7.8563292229999995,-4.092048968,-1461.3020688956603 -2870,2870,E175D,-0.076617398,-2.6899999999999997e-05,-0.016089655,-0.030750039,-0.10061042199999999,0.07244124099999999,-0.120969807,-0.032264988,0.051016942,0.031624782000000004,-0.031678554,-0.0027454999999999997,-0.029433809,-0.006558662,-0.05494141599999999,-0.005168624,-0.19605221899999997,1.245981066,2.677609437,-2.983296437,-2.6456414109999997,-2.786388657,-3.1558368910000003,-3.2451698610000004,-3.0834453660000003,-4.784790538999999,-1.137091138,-1452.2116566323675 -2871,2871,E175G,-0.06587765,-0.050816919,-0.023361972999999998,-0.025041321000000002,-0.280954368,0.050455604,-0.098050026,-0.033705274,0.037089463999999996,-0.0029146090000000003,-0.098719228,-0.0109958,-0.035728146,-0.001636574,-0.048446067,-0.22394856100000002,-0.337960175,1.201525363,1.93779228,-5.573690318,-6.443444167999999,-4.412306511000001,-6.338917885,-6.641439957,-4.032343071000001,-6.13639156,0.270719887,-1453.6665334622376 -2872,2872,E175F,-0.045212979,-0.040929692000000004,-0.010700589,-0.021737995,-0.14040323300000002,0.028848342000000003,-0.12060600199999999,0.030180045,0.019270782,-0.005088418,-0.076770966,-0.02277923,0.001378052,-0.041955785,-0.001520204,-0.139327851,-0.141478614,1.488534738,2.279591948,-7.36818071,-7.689630188,-5.958109451,-7.569274269,-9.008226517,-6.615663124,-6.479535997,-0.808225119,-1458.8786218119785 -2873,2873,E175I,-0.0012650460000000001,-0.041455608,-0.036920166000000004,0.010638908,-0.070853735,0.025260346,-0.027684461,0.025154369,0.038113526,0.011070348,-0.093981563,0.025107018999999998,-0.09894735,0.062070405999999995,-0.04079259,0.018651768,-0.160359237,1.076833718,2.62284945,-3.226594325,-3.9229702000000004,-3.1915204239999997,-3.279470711,-3.5696924969999997,-2.169317795,-4.805841631,-0.46729936299999997,-1465.8488876675256 -2874,2874,E175H,-0.106882981,0.016259186999999998,-0.030562039,-0.0009547389999999999,-0.07025231400000001,0.037388245,-0.134146913,-0.079619049,0.041094934,0.05895549,-0.026437116,0.031693981,-0.09281805800000001,0.047751959000000004,-0.049661435999999996,0.013262804,-0.15376743199999998,1.21664648,2.720926035,-7.860020764,-7.389723061000001,-6.588069534,-8.686639808999999,-9.069827164,-7.565844254,-6.98197814,-1.601440502,-1455.8652306818403 -2875,2875,E175K,-0.050887752,-0.010827625,0.008479525,-0.0025658729999999998,-0.094820258,0.040425428,-0.060680845,-0.041094659,0.05379899900000001,0.046524259000000005,-0.068179509,0.04163954,-0.02468049,0.051135585,-0.05626733,-0.049495742,-0.140144773,1.344604634,2.553957834,-2.571526772,-2.526330353,-2.510010086,-2.58175396,-2.477536705,-2.7620027539999996,-3.988821562,-0.405303067,-1457.051381394267 -2876,2876,E175M,0.005580649,0.02554158,0.006446594,-0.0018265710000000001,-0.065348191,0.0500999,-0.017150891,0.028312188,0.048871498,0.07760550599999999,-0.026522346000000002,0.07213818799999999,-0.059245000000000006,0.023951855,-0.027604997000000003,0.019600532,-0.150296913,1.135845715,2.60945077,-4.705581284,-5.129372704,-4.95989579,-4.1844712369999995,-4.863535187,-4.3906315000000005,-5.949827238999999,-2.1633444230000003,-1463.4336265837774 -2877,2877,E175L,-0.042696057999999995,-0.054942569000000004,-0.017258676,-0.020633989,-0.077029978,0.023793559,-0.065295929,-0.020096186000000002,0.053199697000000004,-0.016991427,-0.09289371099999999,0.027417737,-0.061935089000000006,0.0017688720000000001,-0.043036849,-0.027458191,-0.126601765,1.276755325,2.5206573519999997,-2.341291339,-2.780376762,-2.828326935,-1.539412964,-2.882130959,-1.676209076,-4.031069281000001,0.09268606900000001,-1463.7190842209384 -2878,2878,E175N,-0.031020645,-0.010699658,-0.036052543,-0.020251115,-0.118612428,0.006077944,-0.063020559,0.00097927,0.019345913,0.019697643,-0.041096959,-0.044050646,-0.028054439,-0.014590758,-0.025911472,-0.11465836,-0.122566496,1.4713195980000002,2.3419753919999997,-5.386352327999999,-4.9748358,-5.178721466,-5.810367546,-5.944981353999999,-5.022855476,-5.529574469,-1.5174738630000002,-1454.048471795395 -2879,2879,E175Q,-0.032596096,-0.048933727,-0.027570451,-0.03616869,-0.076423817,-0.019463694,-0.055277954000000004,-0.009914238,0.04569701,-0.0044695970000000005,-0.093397856,-0.028625968999999998,-0.026514932999999997,-0.007586883000000001,-0.06475049599999999,-0.011139013,-0.141708621,1.193999535,2.453429491,-3.777950479,-3.383546555,-4.148035339,-3.91202449,-3.9695091319999998,-3.476636879,-4.920014093,-1.633321715,-1462.1556526720524 -2880,2880,E175P,-0.027726449,-0.023185427,-0.017261061,-0.005796712,-0.04213872,0.005935785,-0.067434976,0.011982079,0.03433395,0.013714965,-0.060085819000000006,-0.005608007,-0.028914113999999998,0.02441245,-0.036005873,0.014872564,-0.099150004,1.207911703,2.739397172,-0.709166814,-0.5467361070000001,0.091913986,-0.34905010200000003,-3.387084854,0.645123009,-2.668306264,0.88450424,-1461.9187124255113 -2881,2881,E175S,-0.029040106,-0.018085041,-0.011261408,-0.007345385,-0.08198592,0.040974413,-0.063455861,0.005375649000000001,0.031119587999999997,0.014804102,-0.050974184000000006,0.026724381000000002,-0.04924719599999999,0.028694716000000002,-0.043385485,-0.01784204,-0.146129799,1.1861051759999999,2.606534576,-4.650903201,-5.249678299,-4.200985237,-4.988620514,-4.91926683,-3.895965126,-6.288125755,-1.904633836,-1459.9877312271856 -2882,2882,E175R,-0.003664968,-0.025145623,-0.020167833,-0.01518402,-0.167412478,0.024712261,-0.039506295,0.032176359,0.017854448999999998,0.013420989,-0.063712235,-0.017100436,-0.02323523,0.007041761999999999,-0.037409802,-0.12187449300000001,-0.212950463,1.51618479,2.407883191,-5.043027803,-4.702225845,-4.693409698,-5.37234581,-5.750666138,-4.696491524,-5.668445932000001,0.159446341,-1457.361357867252 -2883,2883,E175T,-0.049302415,-0.064397945,-0.033498009,-0.020719706,-0.106713349,0.043368414,-0.11239906699999999,0.013794236999999999,0.057213192,-0.031396573,-0.097399316,-0.013700644,-0.053295374000000006,0.01344031,-0.054879722,-0.033051302000000005,-0.18037539600000002,1.537094526,2.782064661,-4.250708008999999,-4.573365196,-3.996172112,-4.150927811,-5.47210939,-3.060965538,-5.302403676,-0.658955582,-1461.2588312062435 -2884,2884,E175W,-0.028465358,-0.027556099,-0.017018591,0.010367648,-0.094118681,0.02304429,-0.07840261,0.021471895,0.075198544,0.014235245,-0.069347442,0.00784658,-0.041883762000000005,0.033199071000000004,-0.012463775,-0.031959226,-0.156278135,1.234983777,2.523943991,-9.056844386,-9.010469367999999,-7.737675606,-9.746597748,-10.3212368,-8.468242409,-7.411446278,-3.4003549439999996,-1458.32879929943 -2885,2885,E175V,-0.013857551999999999,-0.051942445999999996,-0.02632217,-0.01390373,-0.076902895,0.042646736,-0.041868388,0.014153283999999999,0.073395173,-0.032441187999999996,-0.071443703,-0.032431154,-0.020213185,-0.002121189,-0.025686271,-0.034044138,-0.119761652,1.265448124,2.439184837,-1.456077205,-0.9110008009999999,-1.56192775,-1.302009056,-2.2327381969999998,-1.27271022,-3.12519391,-0.360532869,-1464.721951670479 -2886,2886,E175Y,-0.129098959,-0.057639795,-0.049609427000000005,-0.020388088999999998,-0.10930506599999999,0.066133737,-0.138017212,-0.120180706,0.010515573,0.005197638,-0.120477228,0.011034663,-0.110253517,0.033250793,-0.07402697,-0.0005698869999999999,-0.218040244,1.130303773,2.484304809,-8.087906705,-8.679746597000001,-6.101220177,-9.16758889,-8.224896843,-8.266081017000001,-6.2237845,-0.096125799,-1461.7992447968572 -2887,2887,R176A,-0.071857298,-0.026350661,-0.060884604,-0.047761581,-0.8559719859999999,0.18060963600000002,-0.076465699,-0.067248896,0.044583799,-0.026169121,-0.0265322,-0.053905919000000004,-0.067863288,-0.041319787000000004,-0.054203375,-0.746472037,-0.9654719340000001,1.054332027,1.480085921,-11.19985853,-11.74871239,-11.42112824,-11.19811203,-9.601659721,-12.02968026,-6.957355057000001,-2.076338752,-1450.1396285351366 -2888,2888,R176C,0.081896215,0.099546566,0.104517165,0.08105512200000001,-0.5922636139999999,0.067848929,0.06304145,0.10075098,0.093343891,0.11008722300000001,0.08900590800000001,0.09079726099999999,0.118237069,0.09094362800000001,0.071166615,-0.476471638,-0.70805559,1.211113039,1.684792244,-12.6104972,-12.71686913,-12.58791218,-13.00278628,-11.51872523,-13.2261932,-8.426318326,-5.57589878,-1455.0700492672622 -2889,2889,R176E,-0.11772596699999999,0.002897525,0.014373545,-0.055572548,-1.282004161,0.186238877,-0.118580635,-0.116871299,0.016458605,0.020077149,-0.014282099999999999,-0.029786429,0.058533519000000006,-0.073014821,-0.038130274,-1.36727279,-1.196735532,0.887806359,1.345681966,-11.72385191,-13.81853106,-11.33221478,-11.10415488,-10.78763503,-11.576723800000002,-6.969477724,-1.6314722080000001,-1443.6595410299487 -2890,2890,R176D,0.043977391,0.046168442000000004,-0.042369194000000006,-0.094755875,-1.773480238,0.079257619,0.065327048,0.022627732999999997,-0.00680394,0.046136279,0.046200605,-0.065179778,-0.019558608999999998,-0.042928201,-0.146583548,-2.05463958,-1.492320895,0.8205529640000001,1.297180087,-13.03739702,-15.60400839,-13.91822433,-12.09697907,-11.39557787,-12.17219541,-6.152511783,-1.796460224,-1448.2416954268701 -2891,2891,R176G,-0.063106391,-0.022211584,-0.048380919,-0.019576468,-1.789170972,0.063134692,-0.06757661400000001,-0.058636167,0.019344687,0.001609837,-0.046033005,-0.055206884000000005,-0.041554953,-0.020162786000000002,-0.018990148999999998,-1.677332825,-1.901009119,0.466340995,1.303002185,-12.25653717,-12.49552354,-12.97960055,-12.48998045,-11.01876628,-12.29881505,-7.704117196,-3.464066663,-1446.4943476566114 -2892,2892,R176F,-0.078119647,-0.012283503999999999,-0.037038031,-0.074999277,-1.1687866000000002,0.111451446,-0.025873397000000003,-0.13036589699999998,0.008647051,0.069672318,-0.094239326,0.025771687,-0.099847749,-0.009968683,-0.14002987,-0.7718025890000001,-1.565770611,0.829547367,1.4113128519999998,-14.59949924,-15.35678038,-14.62412141,-13.87090638,-11.5357986,-17.60988942,-7.86649232,-4.433807142,-1445.9583648140542 -2893,2893,R176I,-0.06486821799999999,-0.025724652,0.024929708,-0.134505508,-2.562807203,0.053181804000000006,-0.027513064,-0.102223371,-0.060774358,-0.099329099,0.047879795,-0.050975728,0.100835144,-0.10374943800000001,-0.16526157800000002,-2.291552076,-2.8340623289999995,0.969561498,1.277405341,-14.39259583,-14.72611429,-15.62384715,-15.10842486,-9.918622168999999,-16.58597068,-8.268505776,-3.4805710810000003,-1437.7432421850972 -2894,2894,R176H,-0.065217183,-0.007553496999999999,-0.0018129620000000002,-0.049010597,-0.693165748,0.084917602,-0.054914179,-0.075520186,0.020895689,0.007942404,-0.023049398,-0.045968682000000004,0.042342758,-0.061493344000000005,-0.036527849,-0.517046005,-0.86928549,1.759346656,2.020303871,-7.28690563,-8.586422691000001,-7.138146606,-6.891790604,-7.280798775,-6.537369476,-6.114816599,-3.685320462,-1453.3556628138758 -2895,2895,R176K,-0.060087167999999996,-0.056300399,-0.039740914,-0.092763737,-0.250014334,-0.070662839,-0.070374157,-0.04980017900000001,0.13556902699999998,-0.025150391,-0.087450406,0.046887730999999995,-0.12636955800000002,-0.07186029299999999,-0.11366718,-0.158013168,-0.34201550000000003,1.4529990019999999,2.223525207,-8.478686736,-10.51901148,-8.710116287,-8.352342339,-7.075342804,-7.736620766000001,-6.029048124,-2.829217665,-1440.8509532785974 -2896,2896,R176M,-0.07452096,-0.04296967,-0.050676895,-0.016271566,-0.688151548,0.200877917,-0.08569246,-0.063349459,0.209169722,-0.074523659,-0.01141568,-0.06338978,-0.037964009,-0.033254371,0.0007112389999999999,-0.392349386,-0.98395371,1.243076001,1.748497349,-13.289180300000002,-13.66903976,-13.46973713,-14.53101938,-9.737071251,-15.039034,-7.5920538539999995,-4.278713403,-1445.598466440104 -2897,2897,R176L,-0.096856507,-0.033694548,-0.020470089,-0.052466595,-0.760679487,0.137558155,-0.088995025,-0.10471798800000001,-0.013131368000000001,0.0221601,-0.089549196,-0.024171613999999998,-0.016768564,-0.018793781000000002,-0.086139409,-0.60958179,-0.9117771840000001,0.896348162,1.4670576880000001,-9.890960172,-9.530928482,-10.01421451,-12.15523392,-5.55966449,-12.19475946,-6.11180845,-2.045677242,-1446.5533074019477 -2898,2898,R176N,-0.002351286,-0.006509551,-0.011815973,-0.006562266999999999,-0.755379623,0.120316101,0.049573357,-0.054275929,-0.029175372,0.03071047,-0.043729572,0.02260164,-0.04623358599999999,0.008706603,-0.021831136,-0.553123887,-0.9576353590000001,0.708140476,1.4286856030000001,-12.2575676,-14.58612895,-13.07768082,-11.68727044,-11.53003071,-10.4067271,-7.332763012999999,-2.2220546409999997,-1442.0935330959037 -2899,2899,R176Q,0.002410165,-0.033840691,-0.037146003999999996,-0.028296515,-0.097072605,0.034658844,0.006677075,-0.001856745,0.01608072,-0.04228859099999999,-0.02539279,-0.076152514,0.0018605070000000002,-0.011040685,-0.045552345,-0.16658389699999998,-0.027561312,1.4807089519999999,2.244304579,-6.99205938,-7.715565514,-6.932929855,-6.685892288,-6.189306548999999,-7.436602692,-5.47673551,-2.497989822,-1441.8561886278912 -2900,2900,R176P,-0.051587142,-0.015072617,-0.008273108000000001,-1.7197842719999998,-2.9011935230000003,0.00449049,-0.037396287,-0.065777997,-0.002902398,3.64e-05,-0.030181633,-0.023411242999999998,0.006865026999999999,-1.5075487159999998,-1.932019827,-2.5678654290000003,-3.234521617,0.6871522109999999,0.7034870540000001,-12.50421708,-12.31322327,-11.40193111,-14.58711528,-10.66496048,-13.55385524,-7.872245032,-3.6067301360000004,-1448.4854124239646 -2901,2901,R176S,-0.02843112,-0.004567522,-0.025602594,0.001998315,-0.660139414,0.291414187,-0.039150459,-0.01771178,-0.041477825,-0.007555475999999999,-0.001579567,-0.02482301,-0.026382177000000003,0.005701093000000001,-0.001704464,-0.493077651,-0.8272011770000001,0.8587854359999999,1.494811167,-11.41301496,-11.63341774,-10.81336767,-11.84196874,-10.43382599,-12.34249464,-6.11452491,-2.666307065,-1451.1837947424501 -2902,2902,R176T,-0.042435185,-0.019027479,-0.014098273,-0.060936251,-2.210755806,0.062656245,-0.031759347,-0.053111023,0.012096114,-0.006081823,-0.031973135,-0.052582805,0.02438626,-0.002329576,-0.119542925,-1.665677082,-2.755834529,0.578072086,1.308581815,-13.63722695,-12.65398789,-14.43475518,-13.76278414,-12.76957018,-14.56503735,-6.19954912,-1.2771537370000001,-1448.4173417109996 -2903,2903,R176W,-0.10178399199999999,-0.025738565,-0.034434598,-0.06049273,-1.4253905690000002,0.007918399999999999,-0.10989349300000001,-0.093674491,0.021248077,0.013205257,-0.064682386,0.00052512,-0.069394315,-0.021232731,-0.09975272800000001,-1.414016194,-1.436764943,0.681291911,1.322644984,-13.12296577,-12.65916666,-14.40130931,-13.46072641,-10.74812091,-14.34550555,-7.871908125,-2.7454843139999996,-1453.4827561317943 -2904,2904,R176V,-0.08885187300000001,0.005675449,-0.02162835,-0.001205772,-2.112091666,0.085513641,-0.055084439000000006,-0.122619307,0.037619699,0.072465218,-0.061114321,0.038838839,-0.08209553900000001,0.035709838,-0.038121382,-1.5593728359999999,-2.664810495,0.719369325,1.317873495,-13.49466811,-13.84304639,-15.32251915,-14.51787228,-9.483109909,-14.30679281,-7.3998677289999994,-3.264252615,-1438.123860203661 -2905,2905,R176Y,-0.025176067000000003,-0.021198977,-0.035533687,-0.048669883,-1.119486404,0.054994415,-0.030569507000000003,-0.019782627,0.005507186,0.045658139,-0.08805609199999999,-0.060970892,-0.010096481,-0.005130082,-0.092209684,-0.9082931409999999,-1.330679666,0.8668357320000001,1.391633495,-13.44342972,-14.99558603,-14.22862951,-12.56653098,-12.27742448,-13.14897758,-7.867198952000001,-3.7373933010000004,-1444.9247624995187 -2906,2906,D177A,-0.016120823,-0.24444147,-1.853532287,-2.13614782,-2.777766007,-0.042933255999999996,-0.0056260369999999995,-0.026615608,-0.007144463,-0.14413211199999998,-0.34475082700000004,-1.820313279,-1.886751295,-1.874339039,-2.3979566,-2.3728392830000002,-3.1826927310000004,0.7303439409999999,-0.041195301000000004,-14.29781639,-12.32993608,-13.92959061,-13.73057261,-14.12534537,-17.37363729,-7.511382192999999,-4.475968388,-1439.7767086573876 -2907,2907,D177C,-0.03384615,-0.010968565,-0.042513662,-1.9512715719999998,-3.2068331110000003,0.035554672999999995,-0.043325575,-0.024366724,0.012332127,-0.001311963,-0.020625167,0.011560291,-0.096587614,-1.6328871530000002,-2.26965599,-2.84739074,-3.566275482,0.676165595,0.695076903,-16.71855757,-16.12085495,-17.20444671,-15.527494,-16.35352685,-18.38646533,-7.996072771000001,-5.2650840930000005,-1449.5640114028938 -2908,2908,D177E,0.031810139,-0.142519666,-1.3577930319999998,-1.898211186,-2.8871319730000002,-0.045634199,0.036019088,0.02760119,0.02799369,-0.100624641,-0.18441469,-1.4484760730000001,-1.26710999,-1.73411042,-2.062311952,-2.274003349,-3.5002605960000004,3.7510520510000003,2.226345549,-12.98444365,-12.56549814,-12.33393907,-11.69905081,-12.6254398,-15.69829041,-10.38001803,-9.881647741,-1440.8204477555119 -2909,2909,D177G,-0.05066527,-0.019145343000000002,-1.5503802119999999,-2.474242629,-3.096966536,0.403053565,-0.044590772,-0.056739767,-0.005068237,-0.040202634,0.001911948,-1.629233626,-1.4715267980000002,-2.0354419040000002,-2.9130433539999996,-2.8349721430000003,-3.358960928,0.984896232,0.001689835,-13.86645578,-11.76493343,-13.79533993,-12.87650214,-13.902781,-16.99272241,-7.157390032,-2.3757715040000003,-1428.5479630734771 -2910,2910,D177F,-0.040112678,-1.45863092,-2.239600152,-2.703804636,-2.8454228230000003,0.08675874800000001,-0.031420254,-0.048805102,0.046116649,-1.707865145,-1.209396695,-2.0639000259999998,-2.415300278,-2.2148357990000003,-3.192773473,-2.315396034,-3.3754496119999997,-0.324851548,-1.03246806,-19.30167021,-18.54223775,-20.15716284,-17.19859063,-19.46637615,-21.14398369,-9.564736307999999,-7.424561439,-1448.7927557025105 -2911,2911,D177I,-0.039547797999999995,-1.407181644,-2.173694409,-1.8853239030000002,-2.9784870839999997,-0.029232759,-0.032159136,-0.04693645900000001,0.033557843,-1.268532451,-1.545830836,-2.101688587,-2.24570023,-1.951594364,-1.819053442,-2.65421459,-3.302759577,0.260260037,-0.7646454020000001,-18.84272683,-18.46856734,-18.72485277,-17.70716441,-17.28675867,-22.02629095,-8.346648431,-6.332585614,-1444.598706155084 -2912,2912,D177H,-0.057423199999999994,-1.347642099,-2.470607755,-2.42421759,-3.226945425,0.00061601,-0.057239312,-0.057607088,0.048422024,-1.3937092219999998,-1.301574976,-2.3295277000000003,-2.61168781,-2.3043722140000003,-2.544062965,-2.8820537039999996,-3.571837145,-0.332672123,-0.902037139,-13.38927967,-12.34057926,-12.62737952,-11.48412038,-13.46533062,-17.02898856,-6.862055389,-5.009457529,-1442.278867714107 -2913,2913,D177K,-0.07613455200000001,-1.651551649,-2.235122516,-2.670331026,-2.9624642110000003,-0.027912485,-0.058461189000000004,-0.093807914,-0.012706102,-1.464758547,-1.83834475,-2.325943406,-2.144301625,-2.175849184,-3.1648128680000003,-2.577439414,-3.347489008,-0.042119870999999996,-0.931412756,-19.10434258,-17.07863573,-20.78290244,-18.44397006,-17.88225241,-21.33395224,-10.2235114,-9.090818499,-1440.3739087646827 -2914,2914,D177M,-0.037824157000000004,-1.631384144,-1.881562351,-2.607206207,-2.7488243939999997,0.285960998,-0.019709687,-0.055938626,-0.055307599000000006,-1.809139963,-1.453628324,-1.670324823,-2.092799878,-2.5202306,-2.694181814,-2.620790835,-2.876857953,-0.469384865,-1.116083105,-18.96438576,-18.42030879,-19.45063929,-18.54661929,-17.26363905,-21.14072237,-8.807471547999999,-6.75638626,-1447.4120845934376 -2915,2915,D177L,0.007256453,-1.478178075,-2.121342147,-2.519836198,-3.0365156489999996,0.004879856,0.007511955,0.007000951,0.0022333879999999998,-1.5357041790000001,-1.4206519709999998,-2.046641021,-2.196043272,-2.0884323240000002,-2.951240072,-3.143235068,-2.929796229,-0.150182889,-0.971961803,-18.68623285,-17.79818128,-20.19349654,-17.64153305,-16.67184169,-21.12611169,-8.152707216,-6.072712942000001,-1449.002439097967 -2916,2916,D177N,-0.017075801,-0.000158119,0.020908438,-2.070950394,-3.039174838,0.51936255,-0.034688993,0.0005373919999999999,-0.009583795,-0.053688603,0.053372366,0.0030910770000000002,0.038725798,-1.666358636,-2.475542151,-2.72116138,-3.357188295,0.5810482260000001,0.686829747,-9.327629109,-8.96271405,-8.139175437999999,-9.654137802000001,-8.485027817,-11.39709044,-5.162531784,-0.089085383,-1445.8028376144357 -2917,2917,D177Q,-0.029995821000000002,-1.198458333,-2.06711849,-2.4063842369999997,-2.999547418,0.002064553,-0.028396279,-0.031595363,0.045269245,-1.288324378,-1.108592287,-1.614396036,-2.519840943,-2.54348306,-2.269285414,-2.6440432940000003,-3.3550515410000004,2.718566902,0.6131566999999999,-16.24939426,-15.58312479,-16.40857986,-14.11960248,-17.36409329,-17.77157085,-8.388554693,-6.072712742999999,-1438.3847340969369 -2918,2918,D177P,-0.054703996,-1.6308598630000002,-2.136533618,-2.2329946830000003,-2.955764358,0.017016641000000002,-0.034895108,-0.074512884,-0.042048714,-1.7878946219999998,-1.473825104,-2.1581699430000003,-2.1148972930000003,-1.9111657069999999,-2.554823658,-2.58575721,-3.325771505,-0.223047351,-1.0872948070000001,-16.71263022,-16.22572065,-17.16447638,-15.55302508,-16.1109048,-18.50902417,-7.792280456,-4.629567453,-1450.1941383494996 -2919,2919,D177S,-0.040726507,-0.07135499599999999,-1.4137530230000002,-2.164127034,-3.044305848,0.004625543,-0.038938468999999996,-0.042514545,-0.033411471,-0.057048655,-0.08566133599999999,-1.4566244259999999,-1.37088162,-1.94998288,-2.3782711869999997,-2.624574383,-3.464037313,2.76557031,1.203364473,-14.02711028,-12.70172464,-14.80113695,-12.58582555,-12.76977471,-17.27708955,-6.590139751000001,-2.906208201,-1428.6291418951005 -2920,2920,D177R,-0.040080099,-1.58093661,-2.069675444,-2.3295633430000002,-3.254302042,0.026025867999999997,-0.025559633999999998,-0.054600563,0.008478656999999999,-1.691854191,-1.4700190290000001,-1.854069046,-2.285281842,-2.0671527259999998,-2.59197396,-2.804535058,-3.704069025,-0.555157375,-1.06493945,-15.28279183,-15.03369551,-14.868789600000001,-14.6361579,-15.15395259,-16.72136355,-8.268776969,-5.669493051,-1434.5842015305534 -2921,2921,D177T,-0.037308838,-0.889491313,-2.241938641,-2.531019115,-3.24570132,0.00433985,-0.025310124,-0.049307551,0.038496493,-0.860049115,-0.91893351,-2.194720945,-2.289156336,-1.898498686,-3.163539543,-3.145186957,-3.346215683,0.835632919,-0.533736591,-15.52140162,-14.15837387,-16.6662601,-14.83309168,-14.50199335,-17.44728909,-7.483252257,-3.12611923,-1434.8271563528106 -2922,2922,D177W,-0.004003598,-1.293930152,-2.2275420969999997,-2.512235609,-3.193444419,-0.082693571,-0.01816347,0.010156274,0.092009779,-1.4421690719999998,-1.145691231,-2.2848705259999997,-2.170213667,-2.310867562,-2.713603655,-2.712457792,-3.674431045,-0.116619183,-0.898743893,-19.05736052,-18.10889854,-18.69110889,-17.70557104,-19.22812548,-21.55309866,-10.38829928,-9.900579667999999,-1450.4018546706066 -2923,2923,D177V,-0.004413096,-1.392795112,-2.251957696,-2.273133856,-3.264237045,0.013170095,0.00565829,-0.014484481,0.015897236000000002,-1.4737212869999998,-1.311868937,-2.1450266030000003,-2.3588887880000002,-2.074113627,-2.472154084,-2.697552607,-3.830921483,-0.007956959,-0.9253108940000001,-17.61909881,-17.15531444,-17.31167806,-17.08289298,-15.96140543,-20.58420312,-8.600667907,-6.357603388999999,-1444.1052835714072 -2924,2924,D177Y,-0.026625222999999996,-1.440494156,-1.573095255,-2.651457135,-2.3811209509999998,0.26567847,-0.035415302999999995,-0.017835142,0.03599238,-1.652461745,-1.228526567,-1.6105566180000002,-1.535633891,-2.1294691759999997,-3.173445093,-2.008180661,-2.754061241,4.151501698,1.881614181,-19.24181579,-18.29333009,-20.33169232,-16.84428907,-19.51461633,-21.22515112,-10.196313900000002,-9.092938945,-1447.9368040203117 -2925,2925,T178A,-0.03697258,-0.01025819,-0.05929755900000001,-0.666725184,-2.022396221,-0.067034385,-0.03186832,-0.042076839000000005,0.000912627,-0.052362275,0.031845895,-0.09463138,-0.023963738,-0.314931378,-1.0185189890000002,-1.784820715,-2.259971726,1.4962101280000002,1.388526479,-7.5025105420000004,-7.013764388999999,-7.761388725,-6.662048882000001,-8.340127289,-7.735223427,-7.22138722,-2.695679955,-1456.4836852466688 -2926,2926,T178C,-0.003452309,0.022467565,-0.006093559,0.026023947000000002,-1.6754330919999998,-0.045349138,0.010440386,-0.017345003,-0.049738375,-0.014416,0.059351129,-0.06807876,0.055891643,0.016239738,0.035808156,-1.47370052,-1.8771656630000002,0.824484043,1.331275808,-10.492131599999999,-9.741372475,-12.29367126,-9.133995049,-10.94033076,-10.35128847,-8.811347112,-5.556098323,-1454.5253553404473 -2927,2927,T178E,-0.016937156999999998,-0.000344385,-1.103886423,-2.109838908,-2.343746274,-0.071994275,-0.012741378000000001,-0.021132935,0.09272398300000001,-0.050796901,0.050108132,-0.8831370620000001,-1.324635783,-1.72250317,-2.497174646,-2.3261051669999997,-2.361387381,3.059225959,1.758831309,-11.75023141,-11.15071449,-12.37046675,-10.2852391,-13.60105926,-11.34367744,-8.027812092000001,-3.564414251,-1452.8185057118535 -2928,2928,T178D,-0.022743938999999998,-0.078639435,-0.8682324290000001,-1.976704964,-2.8637175839999998,-0.039652777,0.004836025,-0.050323902000000004,-0.0028074320000000003,-0.11326253900000001,-0.04401633,-0.606403739,-1.130061118,-1.715872591,-2.237537336,-2.962927265,-2.764507903,1.989588289,0.944588612,-13.413217999999999,-12.50605766,-15.38231866,-11.48832662,-14.96376373,-12.72562331,-9.296412006,-5.612057393,-1449.280263144523 -2929,2929,T178G,-0.03650891,-0.028961538,-0.16918995399999998,-1.7414818840000001,-2.549241462,-0.07348450599999999,-0.032556597,-0.040461223,0.035529476000000004,-0.074400118,0.016477042,-0.18543152100000002,-0.152948387,-1.4748046019999999,-2.008159165,-2.593316415,-2.505166509,1.273035993,0.778656743,-7.316514032000001,-7.4031984710000005,-6.319113762000001,-7.155837547000001,-6.944204147000001,-8.760216232000001,-7.20122836,-3.217917593,-1450.3222771566361 -2930,2930,T178F,0.019355587,0.038974695,-1.042183748,-1.979926957,-2.86912198,-0.090820779,0.068454157,-0.029742982999999997,0.120552538,0.06893241900000001,0.00901697,-0.704019348,-1.3803481480000002,-1.765234206,-2.1946197069999998,-2.572956186,-3.165287773,1.990801515,0.931855393,-15.12077276,-12.88565914,-18.11985852,-11.88559626,-17.58413857,-15.12861132,-8.204962869,-3.7215851339999997,-1455.5240882802755 -2931,2931,T178I,0.0007364060000000001,-0.041134244,-0.030404400000000005,-1.1708358540000001,-2.0425981159999997,-0.058753062,0.063443801,-0.061970989000000004,-0.067649964,-0.21180971399999998,0.129541226,-0.06514049200000001,0.004331693,-0.853665511,-1.4880061969999998,-1.891836412,-2.19335982,2.2776363219999998,1.644127827,-10.41823583,-9.8630392,-11.86712547,-7.999804581,-13.63960155,-8.721608345,-6.649185841,-3.40908366,-1450.985269788187 -2932,2932,T178H,0.0005205769999999999,0.024717927,-1.111527005,-1.9265255190000001,-2.450143199,-0.055416713,0.040809223,-0.039768068999999996,-0.012970483,0.026397423,0.02303843,-1.006565208,-1.216488802,-1.9601461869999999,-1.892904851,-2.767868167,-2.13241823,2.383297662,1.049441673,-13.65985964,-10.27864773,-16.0813147,-10.12547282,-15.91915819,-15.89470478,-8.224240842,-4.217772212,-1452.1817626291886 -2933,2933,T178K,0.032266966,0.010882636000000001,-1.082954741,-1.99529304,-2.986548055,-0.083049002,0.056949239000000006,0.007584692,-0.039758251,-0.056148862,0.07791413400000001,-0.905966026,-1.259943455,-1.633150628,-2.357435452,-2.741902604,-3.231193505,2.365292051,1.154256435,-11.19116639,-10.86616194,-11.93956719,-9.855000443,-12.25556516,-11.03953719,-8.319398361000001,-2.996720873,-1462.6316757579334 -2934,2934,T178M,-0.159316091,-0.061484069,-0.16277402,-2.053647471,-2.8319181189999996,-0.013901697,-0.151496616,-0.16713556599999999,-0.0068101740000000004,-0.09509483199999999,-0.027873306,-0.19300239,-0.13254565,-1.4177713,-2.689523641,-2.22549328,-3.4383429580000002,2.44000034,1.5028857880000002,-12.05448831,-10.92130016,-13.46398085,-10.87705202,-14.12015848,-10.88995006,-8.851335481,-4.057826899,-1458.656102586072 -2935,2935,T178L,-0.005406741,0.023695416,-0.847496625,-2.061029743,-2.776831022,-0.041987435,0.030624997999999997,-0.04143848,0.027525247000000003,-0.054830529,0.10222136,-0.510537343,-1.184455906,-1.7196141719999998,-2.4024453130000003,-2.754579933,-2.799082111,1.789926526,0.862800013,-10.55280929,-9.718879784,-12.41741207,-9.020177841,-12.91728638,-8.690290352,-6.726409267999999,-2.972375323,-1453.5072564808652 -2936,2936,T178N,-0.075980108,-0.091732399,-0.250229729,-1.4884104180000002,-2.2611833740000002,-0.084548093,-0.074040269,-0.077919947,0.11812856199999999,-0.14138967300000002,-0.042075125,-0.27941978300000003,-0.221039675,-1.5248873790000002,-1.451933456,-2.383761881,-2.138604866,1.5275508169999998,0.836838192,-10.75136899,-10.41841404,-10.40395026,-9.562482758,-12.6922366,-10.67976128,-8.714224377999999,-5.445278977,-1448.5017602839507 -2937,2937,T178Q,0.006552982,0.021178347,-0.057128605,-1.683283735,-2.094211605,-0.08975299199999999,0.008790377,0.004315587,0.006039711999999999,0.01672176,0.025634933999999998,-0.092672314,-0.021584896,-1.493964918,-1.872602551,-2.067603692,-2.1208195169999997,0.8482688509999999,0.7158921229999999,-11.47798253,-10.22602359,-11.54844435,-9.838138466,-12.69812693,-13.07917931,-7.630618371000001,-2.7659674869999997,-1458.75462235976 -2938,2938,T178P,-0.00169372,-1.441202914,-2.1892916159999998,-2.06671496,-2.8639030869999997,-0.07135773599999999,0.001721331,-0.005108771,-0.028500872000000003,-1.5042824240000001,-1.378123403,-2.264243782,-2.114339449,-1.953006939,-2.180422981,-2.821426759,-2.906379415,-0.139205876,-0.9568155359999999,-12.91759115,-12.02074955,-14.03083274,-11.45113136,-14.31534618,-12.76989589,-10.05107184,-6.781916575,-1460.8044111607596 -2939,2939,T178S,-0.003441828,0.0068446340000000005,-0.035690469,0.013058796000000001,-0.131550732,-0.015353438,-0.011624938999999999,0.004741283,0.039652913,-0.038237607,0.051926874000000005,-0.083948522,0.012567585,0.008561019,0.017556572,-0.138716851,-0.124384613,1.385479405,2.213557418,-4.3258371030000005,-3.573637657,-4.60095491,-3.9077006069999998,-5.778857071,-3.768035271,-5.428455129,-1.9022832680000001,-1459.5087803062052 -2940,2940,T178R,-0.025958626000000002,0.010140992,-1.297399273,-2.1593434869999997,-3.014521567,-0.039309601,-0.005521028000000001,-0.046396223,0.026489515,-0.026880177999999998,0.047162160999999994,-1.023374368,-1.5714241780000002,-2.052790334,-2.26589664,-2.537205923,-3.4918372110000004,2.14159828,0.839493752,-11.59679735,-8.757783035,-12.55387045,-10.01925752,-13.36581464,-13.28726111,-6.627665226,-2.4471077130000003,-1459.602185677737 -2941,2941,T178W,-0.03968747,-0.8114099770000001,-1.9583773469999999,-2.182161219,-3.2135716089999997,-0.08717100400000001,-0.02886437,-0.05051057,0.036422341000000004,-0.660259155,-0.962560799,-1.9475083780000002,-1.969246316,-1.956606685,-2.407715752,-2.6016013669999998,-3.82554185,1.604975157,-0.025735342,-14.01355529,-10.822115,-17.47463041,-11.83934553,-14.66753101,-15.26415453,-8.273587702999999,-2.075366433,-1456.4596158065833 -2942,2942,T178V,-0.035448279,-0.007799815999999999,-0.02147337,-0.732749027,-2.349552164,-0.0632658,-0.023071717000000002,-0.04782484,0.011322399999999998,-0.04280928,0.027209649,-0.082907378,0.039960638,-0.339526895,-1.125971159,-2.1161763419999997,-2.582927986,1.4635339719999998,1.331094486,-8.949479036,-9.008019516000001,-9.306102806,-7.444343787999999,-11.92293259,-7.065996475,-6.847592357000001,-2.52747589,-1447.0761749595404 -2943,2943,T178Y,-0.032703631000000004,0.029025183,-1.155732099,-2.469291866,-2.946532519,-0.019010945,0.012512685,-0.077919947,0.11011059,0.0188679,0.039182466,-0.656960112,-1.654504085,-1.96272361,-2.975860122,-2.645506853,-3.247558184,1.795647575,0.77819285,-15.35096205,-11.55716823,-19.14184499,-11.18590287,-17.06402663,-17.80586755,-7.823560892000001,-2.118714087,-1451.4943611705676 -2944,2944,T179A,0.046224395,-0.034006388,-0.184595751,-1.5130488869999998,-1.6994956,-0.097910391,0.013945239,0.07850355,0.009869948,-0.14155141699999998,0.073538642,-0.341185054,-0.028006447,-1.54341548,-1.482682293,-1.756056227,-1.642934972,3.726344202,2.714467013,-5.8438479889999995,-8.64626722,-5.965363625,-4.910584366,-4.901592003,-4.795432732,-6.170942619,-1.78980376,-1462.704120784998 -2945,2945,T179C,-0.049214392999999995,-0.073504932,0.035947226,-0.5907637370000001,-2.572330785,-0.031309429,-0.030145346,-0.06828344,0.041238061,-0.259473637,0.112463773,-0.16937926,0.241273711,-0.48031122299999995,-0.70121625,-2.508529719,-2.636131851,1.41598106,1.171384054,-9.565857422,-9.471306709,-11.46705871,-8.732470367000001,-10.22974149,-7.928709831,-6.901180172999999,-4.175655389,-1460.3893951578066 -2946,2946,T179E,0.012978503,-1.875414462,-2.481677151,-1.923231694,-3.131540263,-0.072050143,0.040023084,-0.014066078999999999,-0.072041998,-2.04604899,-1.704779934,-2.8479470410000003,-2.115407261,-2.062766594,-1.783696793,-2.956648579,-3.3064319460000005,-0.359593094,-1.1574791690000001,-12.78221337,-13.73978926,-13.70065312,-12.21706234,-12.14180316,-12.11175899,-10.68517917,-10.18987442,-1470.5048553827219 -2947,2947,T179D,0.09151922,-1.5481259440000001,-2.477151476,-2.575338244,-2.7044655669999997,-0.133196924,0.09878971199999999,0.084248727,-0.063712592,-1.76322738,-1.333024508,-2.468215418,-2.486087534,-2.586124958,-2.56455153,-2.576916956,-2.832014178,-0.330365872,-1.096292652,-11.93087944,-12.24223439,-13.13375864,-11.28712727,-11.75428349,-11.236993400000001,-9.504102092,-7.616943493,-1469.3708022809587 -2948,2948,T179G,0.049456347000000005,-0.521488732,-1.6614721680000002,-2.159479019,-2.870286433,-0.086859955,0.030095731,0.068816963,0.029438107999999998,-0.436986072,-0.6059913920000001,-1.92799038,-1.394953956,-2.221991178,-2.096966859,-2.7925667730000003,-2.948006093,1.35074276,-0.048739024000000006,-10.47686178,-12.81975514,-10.51406255,-8.826246361,-10.27706812,-9.947176743,-7.421709612000001,-2.512771379,-1459.8031025808305 -2949,2949,T179F,-0.057359255,-1.241090351,-2.102766596,-1.899923368,-2.3300806869999997,-0.029462931,-0.086180462,-0.028538047999999996,-0.132739838,-1.538492942,-0.94368776,-1.942450985,-2.263082207,-1.458300533,-2.341546203,-2.0511525219999998,-2.609008851,4.447149512,2.146055538,-13.66231712,-14.83172106,-14.70609365,-13.40496555,-15.36751414,-10.00129122,-8.241111027999999,-5.475248998,-1461.8237048014998 -2950,2950,T179I,0.11141049800000001,-0.028284634,-1.7451606119999998,-1.780878011,-1.472474702,0.114060975,0.144961393,0.077859603,-0.103968096,-0.081575074,0.025005807,-1.455569893,-2.03475133,-2.0506006869999998,-1.511155335,-1.56427143,-1.3806779740000001,4.204330134,2.6432110719999997,-9.269183092,-10.01742411,-10.88942033,-8.53746151,-11.49598026,-5.40562925,-6.6276994270000005,-2.9091971780000003,-1443.0120240245014 -2951,2951,T179H,0.012877772,-1.303707478,-1.676213252,-2.376460011,-2.505587335,0.059222059,0.008978360999999999,0.016777181999999998,-0.116578179,-1.788370416,-0.8190445390000001,-2.192328458,-1.1600980459999999,-2.3102379969999998,-2.442682025,-2.301029996,-2.7101446730000003,0.141101471,-1.075798029,-13.95466253,-14.28363422,-14.51824043,-12.9535786,-14.23689232,-13.78096706,-10.67763656,-10.15915838,-1474.5049732681364 -2952,2952,T179K,-0.011041428,-1.8222090130000002,-2.100719546,-1.82872497,-2.108367291,0.048145843,0.031302258,-0.053385113,-0.142445147,-2.258192432,-1.3862255940000001,-2.361120478,-1.840318614,-2.178000022,-1.479449917,-2.4698220159999997,-1.746912565,-0.346455695,-1.195983602,-13.45336046,-13.61319967,-14.91137661,-12.61603802,-13.06823528,-13.05795271,-10.68517917,-10.18987442,-1471.0106556187384 -2953,2953,T179M,0.051896884000000004,-0.34882832700000005,-1.243939065,-1.644658584,-1.436712697,-0.14946847900000002,0.02027316,0.083520607,-0.052177685999999994,-0.392206665,-0.305449989,-1.581494542,-0.906383587,-2.09734409,-1.191973077,-1.69019608,-1.183229313,4.55421996,2.8408835310000002,-11.92121004,-13.05763191,-13.21479869,-11.66723624,-12.90897221,-8.757411133,-7.632178917999999,-4.671417629,-1460.630840008147 -2954,2954,T179L,0.0467481,-0.659976033,-1.89705447,-1.961767843,-2.7520048139999997,-0.08142222,0.019748398,0.073747802,0.013447168999999998,-0.602659211,-0.717292855,-2.391328996,-1.402779943,-2.3331472769999997,-1.590388409,-2.323939275,-3.180070352,0.35688753100000004,-0.526893457,-13.51458116,-14.19646787,-15.41489374,-13.4997104,-15.50864189,-8.953191879,-8.188619927000001,-5.50696152,-1446.8141996166669 -2955,2955,T179N,0.134326907,-1.630328298,-2.092827224,-2.191013992,-2.320141315,-0.063187442,0.105464825,0.163188989,0.00038234699999999995,-1.978702114,-1.2819544809999999,-2.08163016,-2.1040242869999997,-2.1995397,-2.182488284,-2.190331698,-2.4499509319999997,-0.48914258,-1.1090614109999999,-10.20093108,-10.10105673,-10.35465483,-10.17658924,-10.52864664,-9.843707977000001,-8.673711929,-6.884448012999999,-1457.2600488914177 -2956,2956,T179Q,-0.015754079,-1.576327813,-1.9903717330000001,-2.4380435030000003,-2.7176858239999997,-0.079204905,-0.019437492,-0.012070666,-0.07939943,-2.031408464,-1.1212471609999999,-2.134336511,-1.846406954,-2.25224605,-2.623840955,-2.544068044,-2.8913036030000003,-0.657770297,-1.14687837,-13.65205633,-14.67012868,-14.11962594,-13.06034309,-13.52339722,-12.88678672,-10.68517917,-10.18987442,-1468.611646658741 -2957,2957,T179P,0.048037519,-1.255365937,-1.751160922,-1.627013075,-1.894521109,-0.050044702,0.016876849,0.079198188,-0.110979975,-1.814699354,-0.6960325190000001,-2.6957786510000004,-0.806543193,-2.336566936,-0.9174592140000001,-2.804480189,-0.9845620279999999,-0.33721347799999996,-1.1339176359999998,-13.30512378,-14.61875855,-13.72397119,-12.90649961,-13.06696815,-12.20942139,-10.52067966,-9.329510657,-1473.4146359805018 -2958,2958,T179S,0.050563725,-0.033441299,-0.016904334,-0.013030818999999999,-0.230557033,-0.10655780699999999,0.010161224,0.090966225,0.018490432,-0.167483567,0.10060097,-0.19897595199999998,0.165167284,-0.21752623399999998,0.19146459600000001,-0.278533761,-0.182580305,1.520701975,2.0156421669999998,-3.07001349,-4.10689785,-3.909756836,-2.394115967,-2.675653084,-2.263643715,-3.048891732,-1.006407282,-1466.7878294899128 -2959,2959,T179R,0.032514294,-1.5332803330000002,-2.152483282,-2.102102574,-2.425682559,-0.047581306,0.029446135,0.035582453,-0.066826989,-1.7905364769999998,-1.2760241890000001,-2.291404533,-2.0135620309999998,-2.35816155,-1.846043598,-2.40010607,-2.4512590480000003,-0.387092355,-1.104469924,-14.185531699999999,-15.46951534,-13.9636358,-13.91841853,-13.70309732,-13.87299149,-10.68517917,-10.18987442,-1472.0377445467748 -2960,2960,T179W,-0.160617163,-1.630715744,-2.390331997,-2.639033763,-2.981145452,0.068954846,-0.094602604,-0.226631721,-0.045164769,-1.710765558,-1.550665929,-2.85508629,-1.9255777040000002,-2.6719658330000002,-2.6061016919999997,-2.963787827,-2.998503077,-0.235915717,-1.0792687970000001,-14.43779244,-14.70340348,-15.49979241,-14.19424425,-15.32971284,-12.46180922,-9.213889826,-6.969712011,-1465.5482202465646 -2961,2961,T179V,0.012128883,-0.058741129,-0.387666413,-2.003287679,-2.521490628,-0.029620795,0.008738108,0.015519658,-0.032369293,-0.18819049,0.070708232,-0.418261019,-0.357071807,-1.8966377419999998,-2.109937616,-2.364550995,-2.67843026,1.6294385930000002,0.766679228,-8.930573801,-10.85512756,-10.00932064,-8.199188515,-10.54125449,-5.047977798,-7.511814427999999,-3.134082269,-1444.0765969990753 -2962,2962,T179Y,0.077284132,-1.522037125,-2.135051049,-1.693647194,-2.36236514,-0.31660366100000004,0.141928553,0.012639711000000001,-0.152335394,-1.704824364,-1.339249885,-2.108782406,-2.161319691,-1.624631955,-1.762662433,-2.217483944,-2.507246335,-0.105173396,-1.096946164,-15.91530202,-16.65486102,-17.0069881,-15.08405989,-16.819863199999997,-14.01073789,-10.68517917,-10.18987442,-1459.8429907034151 -2963,2963,M180A,0.008215116,-0.10665884099999999,-0.058799686,-0.018438764,-0.127120803,-0.03369834,-0.069038768,0.085468999,-0.025102365,-0.109792358,-0.103525323,-0.08330580900000001,-0.034293563,-0.060150237999999995,0.023272711,-0.101332826,-0.152908779,1.522361272,2.396863212,1.091029861,0.839207947,0.965141968,0.656144539,2.549608978,0.445045876,-3.253398392,1.8794693230000001,-1461.7587853185833 -2964,2964,M180C,-0.17364243899999998,-0.074819542,-0.038632127,-0.044083199,-0.117845373,-0.10559689300000001,-0.24841296,-0.09887191699999999,-0.037071311,-0.070126153,-0.079512931,-0.00975172,-0.067512533,-0.049865243,-0.038301154,0.012459399,-0.248150144,1.1765857709999998,2.5441896880000003,-3.036060364,-3.825002327,-2.274353386,-4.606796455,-1.978913582,-2.495236069,-4.212939077,1.755521637,-1460.8030865294859 -2965,2965,M180E,0.060155235999999994,-0.06130517,0.029652502,-0.005679826,-0.04394987400000001,-0.0241386,-0.014978671,0.135289142,-0.038337846,-0.064833865,-0.057776474,0.047726628,0.011578375,-0.026477461,0.01511781,-0.063644971,-0.024254776000000002,1.177169581,2.264657126,-2.833061012,-3.273310051,-1.95759153,-3.94892128,-2.875169098,-2.110313103,-4.812177481,0.5022367529999999,-1458.6396455769427 -2966,2966,M180D,-0.177434819,-0.033802104,0.027280211000000002,0.003269307,-0.39934093,-0.122231075,-0.255733056,-0.099136581,0.004468816,0.011311442,-0.078915649,0.054384287,0.000176135,-0.022982051,0.029520664,-0.189061742,-0.6096201170000001,1.4720809240000001,2.185546032,-3.168685245,-4.3458514710000005,-3.0813708269999998,-4.416568024,-2.95901931,-1.0406165920000001,-4.248461785,0.48121629299999996,-1454.3670907495543 -2967,2967,M180G,0.02159364,-0.09698127,0.012540552,0.006400223000000001,-0.192624745,-0.067349739,-0.144202078,0.187389358,-0.010244841999999999,-0.067990057,-0.125972483,0.054606192000000005,-0.029525088999999997,0.006745484,0.006054962,-0.098737868,-0.28651162199999997,1.37136561,2.355056469,-2.634155504,-2.8252048189999996,-1.850834656,-3.848986977,-1.1446454240000001,-3.501105644,-5.563584284,-1.163148938,-1453.341688294895 -2968,2968,M180F,-0.137961776,-0.073684493,-0.003725579,-0.002144089,-0.296461378,-0.062312282000000004,-0.24364506800000002,-0.032278483999999996,-0.07220663299999999,-0.040356768,-0.107012218,0.09272474800000001,-0.100175905,-0.050662845,0.046374667,-0.212769092,-0.380153664,1.339979813,2.030862812,-5.143784602,-5.451436256,-4.207999901,-7.755996933,-3.907310341,-4.396179581,-7.092650281,-4.335715261,-1459.328384059947 -2969,2969,M180I,-0.17523204899999997,-0.096711958,0.023511436,-0.016955155,-0.22452319399999998,-0.090462333,-0.282816057,-0.06764804,-0.082307511,-0.10730355800000001,-0.086120357,0.09821420199999999,-0.05119133,0.0014348229999999998,-0.035345133,-0.122807939,-0.326238448,1.169010989,2.087660019,-2.2720437999999996,-2.501510033,-2.1388868480000003,-2.2782956469999998,-2.350624977,-2.090901497,-5.855717451,-1.430334393,-1460.8487145779654 -2970,2970,M180H,0.28945582,-0.08986669800000001,0.031378431,0.02238592,-0.061344188,-0.019527701,-0.090929009,0.669840648,0.080077623,-0.004308869,-0.17542452600000003,0.052520283,0.010236578,0.044229715999999995,0.0005421240000000001,-0.015279688,-0.107408688,1.256750483,2.6500553,-3.888426958,-5.178946655,-2.947540154,-6.341737952999999,-2.375853256,-2.59805677,-5.01282071,0.061475632999999995,-1458.7763498187996 -2971,2971,M180K,0.039312705,-0.116649048,-0.041719726,-0.035898887000000004,-0.125447739,0.02902923,-0.10790811199999999,0.18653352199999998,-0.039019485,-0.110229824,-0.12306827199999999,0.06395716900000001,-0.14739662,-0.056104497999999996,-0.015693276000000003,-0.094217154,-0.156678323,1.344368611,2.303353519,-1.7531618530000002,-2.333038963,-0.640192879,-3.2494305110000004,-0.9213417890000001,-1.6218051219999998,-4.3529305019999995,1.252429639,-1462.3490451881662 -2972,2972,M180L,0.173486957,-0.043903289000000005,0.013349803,0.008802413,-0.36966322700000004,-0.013837763999999999,-0.058916825,0.405890739,-0.010640203999999999,-0.04958979,-0.038216788,0.016918341,0.009781264,-0.022956186,0.040561012,-0.297907832,-0.44141862200000004,1.6465103680000002,2.155408192,-1.7630885509999998,-2.2119883419999997,-1.5658427119999998,-1.395887825,-2.436505859,-1.205218018,-4.894440691000001,-0.58010352,-1467.1599822356366 -2973,2973,M180N,-0.15234288599999998,-0.013869412,0.089519141,0.045360487000000005,-0.097824551,-0.025053282000000003,-0.23503605800000002,-0.069649713,0.037788561,-0.010660885,-0.017077939,0.166611058,0.012427223999999999,0.036308645,0.054412329,0.041264341,-0.236913442,1.543610422,3.106887046,-1.740152194,-2.544612305,-0.807760422,-3.898207787,-1.863386719,0.413206261,-3.605959879,1.395519366,-1454.5559126939625 -2974,2974,M180Q,0.824528157,-0.109708877,0.061642395,0.084655964,0.012836888000000001,-0.048919810999999994,0.174265148,1.474791165,0.026832804,-0.061980579,-0.157437174,0.041120486,0.082164303,-0.02497842,0.194290348,0.024319623999999998,0.0013541520000000002,1.1691185590000002,2.719743615,-1.858476291,-2.652852974,-0.990546577,-2.641682213,-1.9173121569999998,-1.089987534,-4.3677654939999995,0.6053690070000001,-1463.6863636816852 -2975,2975,M180P,0.270050771,-0.073583678,-0.073800273,-0.7678384,-1.07766428,-0.08808166099999999,-0.07553401400000001,0.615635555,-0.01053098,-0.063618023,-0.083549333,-0.105932339,-0.041668206,-1.499512912,-0.036163888,-2.064638692,-0.090689868,2.627244526,1.67407162,-1.95131579,-1.337159477,-1.771884178,-3.429864822,-1.115733612,-2.1019368590000003,-4.499697613,0.40678485,-1465.4437269419432 -2976,2976,M180S,-0.012612296,-0.039474102000000004,0.041602301,0.069145843,-0.033144855,-0.056211765999999996,-0.069622843,0.044398252,-0.010363337,-0.023323429,-0.055624775,0.037735647000000004,0.045468955,0.038173095,0.10011859099999999,0.05582306099999999,-0.12211277,1.1570928329999999,2.724819397,3.373192923,4.326895508,3.789994797,1.311933609,4.0986950680000005,3.338445633,-1.5934346169999998,4.733808609,-1454.4230161085725 -2977,2977,M180R,0.20596272399999999,-0.101795828,-0.024229855,-0.003690476,-0.14570540199999998,-0.004266155,-0.058513869,0.470439317,0.012575999,-0.063020753,-0.140570903,0.006324581,-0.05478429,-0.0036083070000000003,-0.003772645,-0.11941776800000001,-0.17199303600000002,1.255915528,2.152573235,-2.215126413,-3.676825005,-0.934614449,-3.457358025,-1.098720741,-1.908113846,-3.948917893,1.811703761,-1460.3519890699536 -2978,2978,M180T,0.054493254000000005,-0.06500485,-0.001645969,-0.024702962000000002,0.02379943,-0.027053503,-0.089290132,0.19827664,0.040511419,-0.06678012900000001,-0.06322957,0.004767404,-0.008059341999999999,-0.069831409,0.020425486,0.037038955,0.010559905,1.6669154590000002,3.6104699410000003,6.01622346,7.249510506,5.492690681,5.487993538,6.1231147,5.727807877,0.43643881799999995,5.898483477,-1455.0303540565073 -2979,2979,M180W,0.015625657,-0.108573852,-0.032831947,-0.008438496,-0.152728798,0.018246246,-0.047578088,0.078829401,-0.053435027,-0.08027087299999999,-0.136876831,0.04164925,-0.10731314300000001,-0.024687286,0.007810295,-0.157597953,-0.147859643,1.326295974,2.132192502,-5.2740229,-5.866425446,-4.635393738,-7.039743561,-4.021189957,-4.807361801,-7.092650281,-4.335714809,-1464.3685807669535 -2980,2980,M180V,-0.035934004,-0.073453965,-0.0005608540000000001,0.01201426,-0.080730722,-0.012497858,-0.134887684,0.063019677,0.005543353000000001,-0.048671887000000004,-0.098236042,0.024519924,-0.025641631,-0.023729635,0.047758155,-0.023238143,-0.138223301,1.412703685,2.6576615169999998,-0.339507751,-1.0944311979999999,-0.026790732999999997,0.20910425600000002,-0.19065786,-0.594763222,-4.064971312,0.503577901,-1463.445701688528 -2981,2981,M180Y,-0.053329242,-0.113604064,0.0046550770000000005,-0.06634654799999999,-0.195293479,0.009574324,-0.115565927,0.008907444,0.02650755,-0.157362281,-0.069845846,0.047225842999999997,-0.03791569,-0.09877155800000001,-0.033921538,-0.10713551,-0.28345144699999997,1.4709603169999999,2.357611993,-5.067096524,-5.700612961,-4.521300133,-8.284508286,-2.576757568,-4.252303673,-5.857609942000001,-0.874274455,-1457.055153009016 -2982,2982,P181A,-0.022723504,0.032185041,0.033034793,0.036470937,-1.419223265,0.040446662,0.028343059,-0.073790067,-0.022621112999999998,0.005747189000000001,0.058622892,0.049784104,0.016285482,0.054753095999999994,0.018188778,-1.2050703999999999,-1.633376129,0.7029418620000001,1.338779173,-5.513981544,-4.651524384,-7.087552382999999,-5.899771355,-5.55784758,-4.3732120210000005,-4.75221122,-1.098045272,-1464.8739098561928 -2983,2983,P181C,0.016975172,-0.044518649,0.017524572,-0.036252022,-1.356029739,0.084111875,-0.108180326,0.14213067,-0.060206304,-0.03174083,-0.057296467000000004,0.047859847000000004,-0.012810704,0.020191933000000002,-0.092695976,-0.880487403,-1.831572075,0.708401941,1.37035961,-11.58361113,-10.5397231,-13.96978693,-11.49255343,-11.05771031,-10.85828185,-8.354583134,-5.905761929,-1461.3544878726825 -2984,2984,P181E,-0.050069249,-1.5264310030000001,-2.304448559,-2.150489505,-2.3740746130000003,0.03711098,0.023577382999999997,-0.123715881,-0.082608655,-1.5106881330000002,-1.542173873,-2.592001413,-2.016895704,-1.8181883819999998,-2.482790628,-2.397223266,-2.35092596,0.160193341,-0.9721001,-13.24538967,-12.36802357,-15.56660244,-12.78681053,-12.95973222,-12.5457796,-10.54740915,-10.48901789,-1463.933656967245 -2985,2985,P181D,0.032789424,-1.589495511,-1.9526825319999999,-2.8523284639999997,-3.1813402539999998,0.031623061,0.08090160099999999,-0.015322754,-0.101493999,-1.6390874009999998,-1.53990362,-2.039159444,-1.866205619,-2.770496392,-2.934160535,-2.9235625439999997,-3.439117964,-0.11719307,-1.0495454659999999,-13.43531346,-13.13638719,-15.67102435,-12.853008500000001,-12.5812394,-12.93490783,-10.54740915,-10.48901789,-1462.724344609771 -2986,2986,P181G,-0.015779644,-0.033697753,-0.0027786729999999997,-1.4818306780000001,-2.424367976,0.062659844,0.020584400000000003,-0.052143687,-0.031522942000000005,-0.062664225,-0.00473128,-0.010419345,0.0048619990000000005,-1.234158767,-1.7295025880000001,-2.323882254,-2.5248536980000003,1.007311317,0.763290707,-11.29686079,-10.63734967,-13.01452847,-11.50004712,-10.96436321,-10.36801546,-8.584840925,-6.048170402,-1458.038156666793 -2987,2987,P181F,-0.150897543,-1.4976213180000002,-2.122247712,-2.283333016,-3.1775116910000003,0.134045505,0.020250001,-0.32204508600000004,-0.13227855300000002,-1.5340988919999998,-1.4611437440000001,-1.8372609219999998,-2.4072345019999997,-2.267567873,-2.299098158,-2.89775528,-3.4572681010000004,0.113428037,-1.010749196,-14.611993700000001,-13.51258096,-17.35671539,-14.41161508,-13.81931097,-13.95974609,-10.54740915,-10.48901789,-1456.769762265496 -2988,2988,P181I,-0.134727095,-0.009458025,0.045668167999999995,-1.310542795,-2.435086889,0.100693126,0.001255364,-0.27070955399999996,-0.134707239,-0.060257251,0.041341202,0.075123068,0.016213267,-0.760302477,-1.8607831119999998,-1.867611139,-3.0025626389999998,1.746575183,1.413475877,-13.21137184,-11.79870509,-15.04863365,-12.29879764,-12.78133774,-14.12938509,-9.039852408,-7.164707093,-1455.2953434959054 -2989,2989,P181H,-0.048541475,-1.103612453,-1.9458272140000001,-2.3420534330000002,-3.0345645880000003,0.06499383,0.003874465,-0.100957415,0.02430223,-1.075014778,-1.1322101279999999,-1.8755014490000002,-2.016152978,-2.247816454,-2.436290412,-2.525821342,-3.543307833,0.263285832,-0.67436389,-13.60648739,-12.81653651,-15.85143327,-13.19150572,-12.92064789,-13.25231357,-10.54740915,-10.48901789,-1461.0816993815824 -2990,2990,P181K,-0.025928549,-1.4660399869999998,-2.003690444,-2.04595424,-3.0845306839999997,0.027155428,0.027781853999999998,-0.079638951,-0.10819102300000001,-1.6451193659999999,-1.286960607,-1.734401576,-2.272979312,-2.118951037,-1.9729574419999998,-2.669957198,-3.49910417,0.060252915,-0.933365305,-13.49401973,-12.43319302,-16.1959659,-12.829382800000001,-12.81952224,-13.19203471,-10.54740915,-10.48901789,-1464.0220261700451 -2991,2991,P181M,-0.098847394,-0.028208582000000003,-0.8415631709999999,-1.790765766,-2.428427535,0.08920609800000001,0.056031599,-0.253726387,-0.117038586,-0.065682235,0.009265071,-0.672307289,-1.010819052,-1.847884265,-1.733647266,-2.6030104080000003,-2.253844661,2.0918136130000002,0.952711018,-11.44955091,-10.40187309,-13.48620638,-11.34645129,-10.89099654,-11.12222723,-8.185210046,-5.818316875,-1458.8661506203935 -2992,2992,P181L,-0.131670244,-0.038127028,-0.183004558,-1.5983319480000002,-2.624131341,0.10703717,0.01461772,-0.277958208,-0.066362607,-0.055855188,-0.020398868,-0.11843617599999999,-0.24757294,-1.458884545,-1.737779351,-2.3321100009999998,-2.91615268,1.039236286,0.7402016,-10.73324673,-9.224401497,-13.28901377,-10.02836897,-10.05376411,-11.070685300000001,-7.053453554,-3.3532029469999998,-1448.6238902960904 -2993,2993,P181N,-0.062651752,-0.735730008,-2.0004596969999997,-2.191598684,-2.972155468,0.065117217,-0.003002056,-0.122301447,-0.020058454,-0.6381467270000001,-0.833313289,-2.226866065,-1.7740533280000002,-2.055113026,-2.328084341,-2.907149183,-3.037161752,0.624403086,-0.49134402299999996,-11.10932125,-10.92237074,-12.75502087,-10.25473325,-10.332674,-11.28180738,-8.370642265,-5.224077195,-1457.6702624629252 -2994,2994,P181Q,-0.091120447,-1.610218476,-2.10104175,-2.002870084,-2.940623847,-0.018370495,-0.058151283,-0.12408961,-0.10869562099999999,-1.6564978869999998,-1.563939065,-1.709782444,-2.492301056,-1.787906877,-2.217833291,-2.8952155389999996,-2.986032155,4.022647929,1.673105928,-11.83239411,-11.01797291,-14.29214009,-11.23801759,-11.179226400000001,-11.43461356,-9.020694037,-7.164707096,-1462.713146590162 -2995,2995,P181S,-0.038313146,-0.038317500000000004,0.007653302,-1.260847925,-2.254049517,0.053807527,-0.002173023,-0.074453269,-0.046064724,-0.06413490599999999,-0.012500094,-0.016631794,0.031938397,-0.817529147,-1.704166702,-2.122883644,-2.38521539,1.9564460069999998,1.404494832,-8.61924234,-8.131993233,-10.19503205,-9.101835182,-8.502683632,-7.164667603,-6.603327967,-3.815972448,-1455.015534168575 -2996,2996,P181R,0.004046027,-1.735702055,-2.0483717969999997,-2.299015958,-3.55518077,0.065697275,0.012324236,-0.004232183,-0.118663829,-1.895500536,-1.575903574,-2.0573334130000003,-2.039410181,-2.099460193,-2.498571722,-3.293919031,-3.816442508,0.000694101,-1.109635779,-13.11717433,-12.41906194,-14.81943009,-12.80895535,-12.73073528,-12.80768898,-10.54740915,-10.48901789,-1462.6538975178264 -2997,2997,P181T,-0.031600892,0.012677177,0.017219461000000002,-0.455022181,-2.108980881,0.054766632,0.028988526,-0.09219031,-0.050446467,0.004298352,0.021056001,-0.006827567,0.041266488,-0.23867121600000002,-0.671373146,-2.016807603,-2.201154158,1.278034174,1.3245107390000002,-7.811983484,-6.2626532589999995,-8.733705687999999,-8.377271499999999,-8.188736382,-7.497550591,-6.145297457000001,-4.13882665,-1451.4880970241502 -2998,2998,P181W,0.040879226,-1.559352892,-1.896963652,-2.583625217,-2.912637008,0.14106328,0.01135693,0.07040152200000001,-0.166681616,-1.723899293,-1.394806491,-2.0270613230000003,-1.76686598,-2.4573682740000002,-2.7098821589999997,-2.610434427,-3.214839589,-0.137028183,-1.129968582,-14.14468692,-13.32915636,-16.88926505,-13.66471542,-13.30778165,-13.53251613,-10.54740915,-10.48901789,-1461.85450745048 -2999,2999,P181V,-0.09007976300000001,0.006426027,-0.018369568,0.009570495,-1.1222861990000002,0.065959908,0.026661527,-0.206821053,-0.030463631,-0.048083497,0.060935551,-0.019064086,-0.01767505,0.027486447999999997,-0.008345458,-0.831464525,-1.4131078730000002,0.6156244679999999,1.3611731440000001,-10.01241568,-9.202768172999999,-11.43838967,-9.349241455,-10.35580881,-9.71587027,-7.680713474,-3.7626661710000002,-1459.8411101931706 -3000,3000,P181Y,-0.001316157,-1.622208455,-2.322468686,-2.13956668,-3.051126408,0.033762493,0.068853851,-0.071486165,-0.121123472,-1.56852284,-1.6758940690000002,-1.898013809,-2.746923563,-1.976138243,-2.302995117,-2.481386913,-3.6208659030000003,0.242438345,-0.979933231,-14.57635852,-13.43875423,-17.40130486,-14.29965802,-13.72607599,-14.01599953,-10.54740915,-10.48901789,-1455.7306480654515 -3001,3001,A182C,0.025894036000000002,-0.035709563,0.03173834,-0.007392236,-0.004182229,0.005275856,0.032091526,0.019696545,0.012138082,-0.076976242,0.005557116,0.02795338,0.0355233,-0.035918838,0.021134366,-0.019605707,0.011241248999999998,1.276755325,2.5206573519999997,-6.119038477,-5.739468948,-6.375403572000001,-6.63780127,-5.360942719,-6.481575874,-5.076847329,-4.590254722,-1461.1245098020881 -3002,3002,A182E,-0.00959176,0.002769044,-0.018941232,-0.032108016,-0.009028851999999999,0.024502577999999997,-0.021744947999999997,0.002561429,0.026587702,-0.04068047,0.046218557,-0.01852068,-0.019361784,-0.041988405,-0.022227627000000003,-0.050964512000000003,0.032906807999999996,1.237588698,2.353131451,-0.049515779,0.344674858,-0.79551416,-0.705582497,0.5499762570000001,0.358866646,-0.908612808,-0.9205022420000001,-1472.3994397888891 -3003,3003,A182D,-0.010321046,0.004460448,-0.038380233,-0.039691878,-0.42100508,-0.039974477,-0.018024089,-0.002618003,-0.007955333,-0.024458627,0.033379523,-0.02865837,-0.048102096,-0.030701684,-0.048682072,-0.34971380399999996,-0.492296355,1.2614721709999999,1.80289256,-1.326406583,-1.882308281,-0.986169266,-1.357856781,-1.726025696,-0.67967289,-2.252444481,-1.445026718,-1470.76173845632 -3004,3004,A182G,0.02474292,0.03109095,0.02683687,0.009605273000000001,0.037299282999999996,0.00696928,0.020250527,0.029235312000000003,0.011781208,0.018232331,0.043949569,0.026464506000000002,0.027209234,0.018020793,0.0011897519999999999,0.031112921,0.043485644000000004,1.086110299,2.62480595,-3.78876118,-3.685652123,-2.9651829989999996,-3.7363082960000003,-3.568226028,-4.988436455,-4.513010148999999,-2.079500819,-1460.1093956627883 -3005,3005,A182F,-0.0042574859999999996,-0.002313163,0.006694042,0.01810184,0.01557299,0.028361985,0.011636674,-0.020151646000000002,0.012579858000000001,0.04583455,-0.050460875999999995,0.047137961,-0.033749877000000005,0.033048262,0.003155417,0.083454082,-0.052308102,1.187700577,2.9060814219999997,-5.899384666,-5.951768166,-6.107528893,-6.410334473,-4.485142113,-6.5421496889999995,-4.748530465,-3.341097594,-1465.9842157894745 -3006,3006,A182I,0.028114987999999997,-0.031001179,0.00765558,-0.007619298,-0.029102077,0.051181332,0.021266757999999997,0.034963217000000005,-0.074029565,-0.053269597,-0.008732761,-0.018920706000000002,0.034231865,-0.046202227,0.030963631000000002,-0.015450191,-0.042753963,1.221686564,2.513350546,-3.07031972,-2.683047493,-3.808281799,-3.440279915,-1.897979225,-3.52201017,-2.445307402,-2.434743257,-1469.4691455173306 -3007,3007,A182H,0.006833372,0.024640912999999997,0.035440031000000004,0.0075225330000000005,0.046813930999999996,0.0035558459999999997,-0.01156469,0.025231434,-0.002397972,0.023484947000000003,0.025796878,0.034870672000000005,0.036009388999999996,0.002165945,0.01287912,0.030381787,0.063246075,1.095078236,2.6286228030000003,-3.9175884169999997,-3.30811161,-4.085450417,-4.71502243,-3.434905853,-4.044451775,-3.133706316,-2.454418826,-1465.653188051656 -3008,3008,A182K,0.10665020800000001,0.017039981000000003,0.069344958,0.058207835,0.071641012,0.021031327000000002,0.077300884,0.135999532,0.019909909,-0.06839861900000001,0.102478581,0.055242747,0.083447169,0.02064001,0.095775659,0.035489328,0.107792696,1.272180895,2.764454626,-1.7681001719999998,-1.420956551,-2.213060387,-2.658405342,-0.683435997,-1.864642586,-2.532186713,-0.679861378,-1466.0614486029372 -3009,3009,A182M,0.063272862,-0.018380102,-0.025762652999999996,-0.011764165,0.02676237,0.104492139,0.116584602,0.009961121,0.051071299,-0.057193315,0.020433112,-0.061362464000000005,0.009837159,-0.015926133000000002,-0.007602195999999999,-0.022789666,0.076314406,1.281820378,2.54075862,-4.570704352,-4.386302979,-4.846672096,-4.97599807,-3.894245148,-4.750303467,-4.018196716,-3.28021597,-1468.5653062909842 -3010,3010,A182L,-0.000940848,-0.007574905,0.052682988,0.019510469,0.023923761,-0.028036942999999998,0.02475238,-0.026634075,0.007588534,0.015478001000000002,-0.030627811,0.046461632,0.058904343,0.034004837,0.005016100999999999,0.04102483,0.006822691999999999,1.2536779040000001,2.843603555,-2.790549126,-2.512883537,-3.042941605,-2.268565147,-2.126583397,-4.0017719419999995,-2.755636434,-1.088699649,-1468.0943647706881 -3011,3011,A182N,0.055181494000000005,0.029055925,0.013848575,-0.011045558,-0.025473966,0.019931853,0.06925809299999999,0.041104893999999996,-0.015353459,-0.02333283,0.081444679,-0.048063787000000004,0.075760937,-0.041857985,0.019766869,-0.036723036,-0.014224895,1.346056256,2.522759118,-1.3062665740000001,-0.925605583,-1.2738601,-2.106773369,-0.621586578,-1.60350724,-2.398780227,-1.444579874,-1469.7279822784476 -3012,3012,A182Q,0.002359254,0.08445270099999999,0.03631002,0.035223233,0.008577633000000001,0.038149821,0.010126007,-0.0054075,0.034397991,0.06317485099999999,0.10573055,0.05659220400000001,0.016027836,0.026528926,0.04391754,0.021308992000000002,-0.004153727,1.2154302959999999,2.8533437680000002,-1.8209457569999998,-1.4743611909999998,-2.05743457,-2.280425407,-1.041883675,-2.25062394,-2.7213743439999996,-1.696564811,-1470.9971705963835 -3013,3013,A182P,0.001457656,-0.02581082,0.002850225,-0.015261643,-1.656836061,-0.029733932999999997,0.014654502,-0.011739191000000001,-0.000585316,-0.023340593,-0.028281047,-0.022894422999999997,0.028594872,-0.031207267,0.0006839810000000001,-1.541237199,-1.772434923,0.7690644729999999,1.323497125,-6.62325748,-6.56815416,-6.906690308,-7.071876045,-5.447978241,-7.121588646,-5.735882589,-4.541173962,-1457.9248698973097 -3014,3014,A182S,-0.026177605,-0.03523688,0.008293303,-0.010591371,-0.006001543000000001,-0.009138009,-0.032693259,-0.019661951,-0.019298918999999998,-0.023383342,-0.047090417,0.010396806,0.006189799,0.018418045,-0.039600786,0.020346033,-0.032349117999999996,1.1336280429999999,2.7783424119999998,-2.0529901059999998,-2.421104118,-2.0598083419999997,-2.394002342,-1.015357262,-2.374678467,-2.324410797,-1.4196967969999998,-1461.983861307148 -3015,3015,A182R,0.025848383,0.00464593,0.021281539,-0.003368994,0.020417383,0.002075713,0.030925892000000003,0.020770873000000002,-0.010317935,-0.013232296999999999,0.022524157000000003,0.012336755,0.030226322000000003,-0.010593766000000001,0.003855778,-0.002532481,0.043367246,1.212823993,2.588918956,-1.606787746,-0.928863205,-1.811418785,-2.4280829319999997,-1.085835442,-1.779738365,-1.516146613,0.519177056,-1466.017912815325 -3016,3016,A182T,0.012578783,-0.0022448520000000003,0.031140745,0.025650758,-0.023171976,0.009294604,0.014848667,0.010308898,0.0027156520000000003,0.008608254000000001,-0.013097958,0.041812201,0.020469288000000002,0.046609433,0.004692083,-0.012757814,-0.033586137,1.156526309,2.563583434,-2.522444884,-2.611330223,-2.7438612439999996,-2.951888542,-1.6708596569999998,-2.6342847519999997,-3.0411509760000004,-2.246883451,-1464.2112593026832 -3017,3017,A182W,-0.01898659,-0.018896031,-0.000376701,-0.018677241,0.024065487000000003,-0.008680061999999999,0.037002792,-0.074975971,0.021440265,-0.09683879,0.059046728,-0.071970294,0.071216892,-0.112318617,0.074964135,-0.044631391,0.092762364,1.259706967,2.367387496,-6.386762497,-5.934479645,-6.44431575,-6.751424736000001,-5.699582747999999,-7.104009605,-5.296708265,-4.364194988,-1463.0037366608158 -3018,3018,A182V,0.013361785,0.013922575,0.01616376,-0.02134548,0.022611642,0.008248703000000001,7.159999999999999e-05,0.02665197,0.011941461,-0.006353799,0.034198948,0.013599723000000001,0.018727797,-0.015563671999999999,-0.027127288,0.000869037,0.04435424599999999,1.183886993,2.526818017,-2.094048015,-1.9810862580000002,-2.7580858760000004,-2.124738396,-1.560268433,-2.0460611109999998,-0.9828831990000001,-1.9543969280000002,-1467.4644858576357 -3019,3019,A182Y,0.003872978,-0.045122269000000007,0.01585435,0.01144438,0.039926567999999996,-0.011408198999999999,-0.022898875,0.03064483,-0.011054841000000001,-0.052772977,-0.037471561,0.01319002,0.018518679,-0.024094922,0.046983682,0.037652938,0.042200197,1.219011973,2.738503741,-4.789803189,-4.535424896,-5.09901075,-6.003264907999999,-3.1786558080000002,-5.132659584,-4.547569096,-1.662790943,-1461.6088325344026 -3020,3020,A183C,-0.023740565,-0.074572573,-0.034712441000000004,0.028587076,-0.496674031,0.012805835,0.011003116,-0.058484245,0.06553355400000001,-0.024268642000000003,-0.124876504,-0.019668589,-0.049756292,0.019267825,0.037906326000000004,-0.357078711,-0.636269351,1.260685515,1.809424226,-7.844315279,-7.741622307,-7.933077751,-8.926923927,-8.00489801,-6.615054398,-6.940710673,-6.808251863,-1456.3544519762509 -3021,3021,A183E,-0.072080794,0.012492863,-0.024964232000000003,0.010272526,-0.11130274400000001,-0.005970805,-0.022313125,-0.121848463,-0.009832961999999999,0.014263518999999999,0.010722207,-0.050594075,0.0006656110000000001,-0.034310701,0.054855752,-0.122446519,-0.100158969,1.318359053,2.187937015,-5.878227106000001,-5.970086739,-5.952479385,-6.762154678,-5.870847382000001,-4.835567345,-4.593363869,-1.3540050119999998,-1444.8334771632217 -3022,3022,A183D,-0.050307149,-0.021346665,-0.044231979000000005,-0.029827562000000002,-1.46783653,-0.116659157,-0.017231761,-0.083382537,-0.017901732,-0.10826421300000001,0.06557088400000001,-0.07387401,-0.014589946999999999,-0.076431073,0.01677595,-1.192238584,-1.743434475,1.160131034,1.415927472,-6.399778052,-6.758212006,-6.66582428,-8.458146935,-5.678406662,-4.438300377,-4.961661067,-0.638759628,-1449.4010240063071 -3023,3023,A183G,-0.031872006,0.006684963,0.000783183,0.017655141000000003,-1.016716013,0.01170527,-0.010363366,-0.053380646,-0.011716642,-0.000943303,0.014313228999999998,0.016722535,-0.01515617,-0.003360873,0.038671154,-0.744340076,-1.28909195,0.7423276259999999,1.396991794,-6.106286494,-5.870678283999999,-7.522611496000001,-5.873915527,-6.097609818,-5.166617348,-4.528649948,-2.596448566,-1452.2698060409166 -3024,3024,A183F,-0.014698798999999999,-0.0005133269999999999,0.0028363859999999998,0.040355472,-0.294205693,-0.012090097,0.012583759,-0.041981356,-0.003670362,0.021331706000000002,-0.022358358999999998,0.046922878,-0.041250107,0.052859971,0.027850972999999998,-0.186838521,-0.401572865,1.4269208080000002,2.208931766,-8.013651286,-8.201744965,-7.801592529,-9.079235298,-8.343025909,-6.64265773,-6.021257791,-5.881729214,-1452.604943655897 -3025,3025,A183I,-0.087892656,0.035942818,-0.013414603999999998,-0.021887097999999997,-0.133558866,0.025184544,-0.064135072,-0.11165024,0.016256034,0.028260409,0.043625227,-0.015988105,-0.010841102,-0.004967501,-0.038806693999999996,-0.13286752,-0.134250211,1.406169601,2.276767748,-6.148597092,-4.9782590639999995,-6.663653427000001,-6.891743996000001,-7.486657944,-4.722671028,-4.973782923,-5.450722995,-1450.375110308174 -3026,3026,A183H,-0.027769589,0.029980958,0.018963983,0.07515109,-0.054851679,0.056062135,0.056747148,-0.112286325,-0.018488336,0.035074583,0.024887332,0.05868095,-0.020752985,0.057256338,0.09304584199999999,-0.038863067,-0.07084029,1.337756992,2.657346233,-6.587671126,-6.100622894,-6.888728844,-7.197893127,-6.896612762,-5.8544980010000005,-5.416575754,-5.57364442,-1447.5765525731258 -3027,3027,A183K,-0.079786219,0.070580846,0.019954088999999998,0.035759714,-0.20409440899999998,0.18301646300000002,-0.013853022,-0.145719415,-0.034187436,0.090067559,0.051094132,0.032316574,0.007591604,0.06951444799999999,0.002004979,-0.140592685,-0.267596133,1.293486817,2.263247798,-6.869062679,-5.962195662999999,-6.86391848,-7.370639015,-7.243000031,-6.9055602039999995,-6.0737042379999995,-6.128698094,-1451.4592404635623 -3028,3028,A183M,-0.022916669,0.025154984,-0.010412791,0.05120098,-0.051695839,0.076707174,0.001196196,-0.047029533,0.015877991,0.002706305,0.047603662000000005,-0.048172789,0.027347207000000002,0.042140684000000005,0.060261275999999996,-0.114492745,0.011101067,1.488885611,2.4301926259999997,-7.778223017999999,-7.573919891,-7.802128952,-8.486162415,-8.451562912,-6.577340919,-6.471527939,-6.348745482999999,-1453.0378811671399 -3029,3029,A183L,0.004790857,0.015188071000000001,0.0011007669999999999,0.034230046,-1.5403384919999998,-0.02093112,0.043034715,-0.033453002,0.018144701000000003,-0.006663838,0.037039979,-0.015826025,0.018027559,-0.011499587,0.079959679,-1.293096792,-1.787580191,0.66413936,1.32976294,-8.379285672,-8.860889862,-8.148057724,-8.486375633,-9.509835953,-6.891269188,-6.885983322,-6.797286955,-1445.2482570344582 -3030,3030,A183N,-0.010368569000000001,0.13849968699999998,0.108948948,0.065015831,-0.045816635999999994,0.13263534,0.043910236,-0.06464737400000001,-0.014408185,0.11382845400000001,0.163170919,0.136979355,0.08091854,0.058701579000000004,0.071330082,-0.037761685,-0.053871587,1.263124486,2.561599786,-7.226848824,-7.335209869,-8.30918631,-8.547865791,-6.643646317000001,-5.298335831,-5.3175541719999995,-5.931441132000001,-1447.0447935373522 -3031,3031,A183Q,-0.04792725,-0.006727528000000001,-0.0054702430000000005,0.046720674000000004,0.021676400000000002,0.020411749,0.002613695,-0.09846819400000001,-0.002194047,-0.008256425,-0.00519863,0.030469296,-0.041409781,0.048577706,0.044863640999999996,0.034903667,0.008449133000000001,1.140736053,2.886318976,-5.783172508,-6.314887924,-5.959453948999999,-5.916889038,-5.36286776,-5.36176387,-4.989368692,-3.4316653039999996,-1442.8262896439992 -3032,3032,A183P,-0.00692299,0.013912668000000001,-0.005354032,0.007483119,-1.311531959,0.01665132,0.01054576,-0.02439174,0.0038179309999999997,-0.01723911,0.045064445,-0.014249766,0.0035417020000000003,-0.02091119,0.035877427,-1.152182433,-1.470881485,0.8631850409999999,1.362019224,-7.664703239,-7.984884499,-7.473240112,-7.646140663,-8.298527817,-6.9207231060000005,-6.18386213,-6.558032337,-1458.5837315390818 -3033,3033,A183S,0.004189247,0.020845917,0.04006587,0.052767135,0.021753513999999998,0.086922835,0.00630405,0.002074443,-0.020718484,-0.00756658,0.049258413,0.052223007,0.027908732000000002,0.034220468999999996,0.071313801,-0.004006541,0.047513569000000005,1.214737186,2.698344568,-2.80359147,-2.8087982410000003,-2.821316719,-3.653611824,-2.9006793369999997,-1.833551231,-2.4301824659999998,-2.5327454990000002,-1454.756936932914 -3034,3034,A183R,-0.044648701,0.034571484,0.025576052000000002,0.041527768,-0.23113567899999998,0.117625837,-0.01087788,-0.078419522,-0.040965376,0.041600222,0.027542745,0.036784646000000004,0.014367458,0.036814457,0.046241078,-0.19776836600000003,-0.264502992,1.379225858,2.133583363,-5.627004177999999,-5.356586716,-5.559105499,-5.964864937000001,-5.772650436,-5.481813301,-4.526437371,-5.114088888,-1445.987198012881 -3035,3035,A183T,0.009534147,0.022548666000000002,0.017386302,0.026470987999999997,-0.049025112999999995,0.062015333,0.0257282,-0.006659906,-0.016233941,-0.024345646000000002,0.069442977,0.043641877,-0.008869273,0.017900777,0.035041197999999996,-0.055557163,-0.042493063,1.384011385,2.5328971780000002,-4.627655847,-4.436845459,-4.38423735,-5.488062157000001,-5.17014843,-3.65898584,-4.357644843,-4.012949689,-1445.769949418027 -3036,3036,A183W,-0.0044056370000000004,0.001477268,0.018696625,0.049261263,-0.652367159,-0.022517626000000002,0.0058387890000000005,-0.014650062,-0.024290331000000002,-0.027612752,0.030567287999999998,0.029769385,0.007623865,0.032395928,0.066126597,-0.505342675,-0.799391643,0.657164259,1.425774123,-9.324683206,-9.037518616,-9.63349144,-10.18596162,-9.498445976000001,-8.267998375,-7.37028396,-7.468670416,-1449.4863421390764 -3037,3037,A183V,-0.021128737999999998,0.0035350190000000004,-0.00441787,0.02467123,0.016607528,-0.013892601999999999,-0.029002046,-0.013255428999999999,0.020636236000000002,0.023558025,-0.016487987,0.031436545,-0.040272284,0.023680887,0.025661572,0.008400803,0.024814252000000002,1.008546763,2.519511482,-5.494781103999999,-5.139751915,-5.945951309,-5.907063003999999,-6.228166946,-4.252972343,-4.836063896000001,-4.851513624,-1448.2470649643801 -3038,3038,A183Y,-0.089999149,-0.032048744,-0.005827854,0.030016786,-0.110270561,0.063862655,0.025528348,-0.205526645,-0.019529004,-0.035800692,-0.028296795,0.049182425999999994,-0.060838132999999996,0.104902001,-0.04486843,-0.077621385,-0.142919737,1.565538519,2.7509177719999998,-8.983895396,-8.474588554,-9.314401512,-10.04879456,-9.276488579,-7.805203774,-7.1678989589999995,-7.003888666,-1447.92973655276 -3039,3039,M184A,-0.007670949,-0.020116936000000002,0.006407441,-0.0028028140000000003,-1.6210737730000002,0.022686319,0.00023627099999999997,-0.015578169,-0.00586538,-0.070231697,0.029997825,-0.06894379,0.08175867099999999,-0.044599555,0.038993928,-1.510267403,-1.7318801430000001,0.817772387,1.328862368,-4.038409366000001,-2.821572563,-2.267180717,-4.046127434,-6.943618622000001,-4.113547493,-2.75325925,-1.76688287,-1449.760065493174 -3040,3040,M184C,-0.020024225,-0.029760362000000002,-0.04711831599999999,-0.133387095,-1.7155351230000002,0.023287305,-0.013314856000000002,-0.026733592999999996,-0.008535606,-0.095538359,0.036017635,-0.123292216,0.029055584,-0.18323445600000002,-0.083539733,-1.8585895000000001,-1.572480745,1.2707733140000002,1.3422901740000002,-10.57965297,-10.12723325,-10.21311843,-11.12700714,-11.11027993,-10.32062612,-6.64778528,-4.1448565230000005,-1460.4605928421952 -3041,3041,M184E,-0.025726777000000003,-0.538535152,-1.883190287,-2.1405338940000003,-3.163032745,-0.01911326,-0.031310591,-0.020142962,0.049525513,-0.556608357,-0.520461947,-2.005917932,-1.760462641,-2.110375725,-2.170692063,-3.0418593439999997,-3.2842061460000003,1.3449792880000002,-0.138641063,-11.82663974,-10.08517387,-11.18203423,-12.73722656,-13.23491512,-11.89384892,-8.477782357,-7.311449822,-1456.3267513238825 -3042,3042,M184D,-0.022784556,-1.4611365769999998,-2.117561804,-2.373392185,-3.260115432,-0.01331702,-0.008812968000000001,-0.036756143,0.043490789,-1.81738331,-1.1048898440000001,-2.016815411,-2.218308197,-2.280974047,-2.465810322,-3.098514313,-3.4217165510000003,-0.8986693309999999,-1.084774251,-12.72151038,-11.70678309,-12.25896468,-13.55826331,-13.52048732,-12.5630535,-8.455645721,-7.311449822,-1457.6620343099348 -3043,3043,M184G,-0.009993944,-0.071870612,-1.236829301,-2.288690503,-2.794416557,-0.001076434,-0.006959730999999999,-0.013028156,-0.013340952,-0.134843138,-0.008898086,-1.329074046,-1.1445845559999999,-2.365780054,-2.211600951,-2.732992243,-2.8558408710000003,0.940209545,0.09253781,-11.56411057,-10.72810131,-10.15459177,-12.20526958,-12.80588436,-11.92670584,-7.603322852000001,-6.429024149,-1454.3111787554808 -3044,3044,M184F,-0.003377559,-0.072998573,0.006555256999999999,0.003948701,-0.249223794,-0.039049432,-0.028332662,0.021577545,0.015121633,-0.17123382199999998,0.025236677000000002,-0.021863146,0.03497366,-0.033017138,0.04091454,-0.247929337,-0.25051825,1.140336024,1.814768816,-8.373350099,-8.203760658,-7.4688407670000005,-10.22778327,-9.080827872999999,-6.8855379260000005,-4.6583522660000005,-2.37067667,-1448.0019834856503 -3045,3045,M184I,-0.044003885,-0.03799069,-0.021033345,-0.023959977,-0.030925581,-0.024640397,-0.081307886,-0.006699883,-0.004753877,-0.101752871,0.025771492000000003,-0.104831404,0.062764714,-0.08306746200000001,0.035147509,-0.10293785800000001,0.041086696,1.487893931,2.280312823,-2.683348854,-3.0961340560000004,-1.602787537,-2.588182571,-2.91251609,-3.217124016,-2.641580762,-1.215989802,-1458.0189487119205 -3046,3046,M184H,-0.027584913,0.008232975,-0.784877343,-2.1569684209999997,-2.983621742,-0.035995858,-0.04206656,-0.013103265,0.034128337,-0.045686038,0.062151987,-0.8623063240000001,-0.707448361,-2.107441723,-2.2064951180000003,-3.071110025,-2.8961334589999996,1.9139221730000002,0.7402522779999999,-12.61571819,-11.68289847,-11.76393416,-14.61086838,-13.69763052,-11.3232594,-7.318412138999999,-5.511316138,-1455.7303530201316 -3047,3047,M184K,-0.006939745,-0.21001071899999998,-1.462295766,-2.250184896,-3.088453138,-0.035299311,0.000431732,-0.014311221,-0.006877716,-0.312757247,-0.107264191,-1.606194371,-1.318397161,-2.268293015,-2.232076776,-2.988923269,-3.187983006,1.382772735,0.101620915,-11.11077219,-10.32923153,-10.69055606,-12.16669569,-11.16723736,-11.200140300000001,-8.124188417000001,-7.246977239,-1460.4404898365028 -3048,3048,M184L,-0.030075035,-0.028226341000000002,-0.006117206,-0.006625001,-1.189826062,0.055857884000000003,-0.009336543000000001,-0.050813526,-0.042033468,-0.09017529099999999,0.033722609,-0.044139541,0.031905129,-0.06641414400000001,0.053164143,-0.947066346,-1.432585777,1.018525895,1.4228271719999999,-5.231478915,-3.5013105010000003,-6.823992615,-6.018652817,-3.911836884,-5.901601761,-4.071945976,-0.69792654,-1454.054291435983 -3049,3049,M184N,-0.023103461000000002,-0.086900743,-1.345229326,-2.7798192339999996,-2.6419334709999998,0.009281224,-0.00953136,-0.036675562,-0.016386015,-0.124876011,-0.048925474000000004,-1.446220394,-1.244238258,-2.965651535,-2.593986932,-2.7831918019999997,-2.500675139,0.855042648,0.059992314000000005,-13.68347434,-13.30268517,-14.36115207,-14.4030263,-13.54781538,-12.80269277,-9.326089300000001,-9.664162641,-1457.3617503698915 -3050,3050,M184Q,0.000468201,-0.00638453,-0.0026175260000000002,-1.22788001,-2.403221462,-0.015237536999999999,0.011237495,-0.010301094,0.037093219,-0.118413305,0.105644246,-0.06450740099999999,0.059272349,-1.050525125,-1.4052348940000001,-2.399544309,-2.406898615,1.1511333940000001,0.830686873,-9.331905232,-7.500102577000001,-10.04270785,-9.598024231,-10.18674187,-9.331949631,-6.468126871,-3.659458868,-1459.6266374844126 -3051,3051,M184P,-0.033028056,-1.1658595379999999,-2.190393164,-2.459885108,-3.0305967480000002,0.023086796,-0.028939626,-0.037116485,0.034720581,-1.404563305,-0.9271557709999999,-2.441268109,-1.939518219,-2.404396749,-2.515373466,-2.823997007,-3.2371964889999996,-0.34054697799999994,-0.894739244,-12.56093716,-11.8125698,-11.99774866,-13.22729124,-13.44295313,-12.32412296,-9.326089300000001,-9.664162641,-1457.2978151389398 -3052,3052,M184S,-0.036268838,-0.050471957000000005,-0.144130785,-1.6463386080000002,-2.6635718440000002,-0.031259726,-0.031543918,-0.040993757,-0.001026068,-0.065144434,-0.035799479,-0.20694725600000002,-0.081314314,-1.4866180580000001,-1.806059157,-2.50045297,-2.826690717,1.320393414,0.7875367659999999,-8.532345021,-7.717809944,-7.782505623,-9.483253288,-8.882892715,-8.795263535,-5.336343538,-3.508296399,-1458.3077570879832 -3053,3053,M184R,-0.026353005,-0.982419905,-2.055137769,-2.383815128,-3.190159524,0.0016039370000000002,-0.021947307000000003,-0.030758702000000002,0.063149733,-1.169817145,-0.7950226640000001,-2.178434731,-1.931840807,-2.388235704,-2.379394552,-2.6580736419999997,-3.7222454060000003,0.28323706600000004,-0.715703706,-13.02766366,-12.08396581,-13.78701694,-13.48815012,-13.62352993,-12.1556555,-9.326089300000001,-9.664162641,-1459.00310405856 -3054,3054,M184T,-0.028301438999999998,-0.022840129,-0.20830825600000002,-1.775472161,-2.579511712,-0.034067697,-0.040733128,-0.015869749,0.031913636,-0.082711278,0.03703102,-0.279519236,-0.137097276,-1.80954345,-1.741400871,-2.706264963,-2.4527584609999997,1.406133536,0.7456390509999999,-7.814627203,-8.25908773,-6.546794952000001,-8.056327797,-8.676142319,-7.534783217999999,-5.65910034,-2.945930287,-1454.5996295246296 -3055,3055,M184W,-0.027345065,-0.426407951,-1.856941516,-2.3239542,-2.987315471,0.07787624900000001,-0.025250714,-0.029439415,-0.034900461,-0.5141916529999999,-0.33862424799999996,-2.059732125,-1.654150906,-2.113037395,-2.534871004,-3.044521014,-2.9301099269999997,1.28670345,-0.16612846,-11.20513373,-10.83834392,-11.13614493,-11.35315315,-12.77808223,-9.919944443,-5.935094891,-4.689412066,-1452.790022133384 -3056,3056,M184V,-0.010718105,-0.003280458,0.000209717,0.018757403,-0.284368235,0.021091874,-0.003974027,-0.017462183,-0.010998272,-0.056504165999999995,0.049943250999999994,-0.052838555999999995,0.05325799,-0.018361894,0.055876699999999994,-0.301096378,-0.267640091,1.7439615119999998,2.278832726,-3.997260645,-3.6290795439999997,-3.247514778,-3.8713630219999997,-4.074196632,-5.164149246,-3.215703332,-2.117353853,-1449.9916418213397 -3057,3057,M184Y,-0.041376596,-0.000320622,0.033301208,-0.005854532,-0.49620861200000005,-0.023330057,-0.047050813,-0.035702379,-0.058189134,-0.038450251,0.037809008,0.010090914,0.056511502000000005,0.002429874,-0.014138938,-0.433090529,-0.559326694,1.281431829,1.724732943,-10.32741354,-10.45575513,-8.924756996000001,-11.72473989,-11.73938422,-8.79243148,-5.635672965,-2.9022250130000002,-1452.2308048182167 -3058,3058,A185C,-0.008064639,-0.015629525,0.031268952,-0.0017766379999999999,-1.555559949,-0.022926801,-0.011571598,-0.00455768,-0.110207351,-0.029697519,-0.0015615310000000001,0.047631229000000004,0.014906675,-0.012775028999999999,0.009221754,-1.253067441,-1.858052456,0.6388492579999999,1.327233339,-6.925337575,-7.786796798999999,-7.493366028,-5.923378067000001,-5.297143753,-8.126003227,-5.859515987000001,-3.4709962410000004,-1464.2302067573182 -3059,3059,A185E,-0.004151671,-0.91591615,-2.07866261,-2.316155505,-2.788667675,-0.041549822,-0.015255826,0.006952485,0.078265061,-1.059552997,-0.7722793029999999,-2.255501176,-1.901824044,-2.74222049,-1.8900905190000001,-2.613916138,-2.963419211,0.238378602,-0.6735804129999999,-7.930037502999999,-8.338119995,-8.137184494,-7.271108673,-7.216540054,-8.687234299,-6.779089593999999,-4.659426992,-1470.3591614370234 -3060,3060,A185D,-0.020693382,-1.175518417,-1.9717470940000001,-2.398618334,-2.268067522,-0.038378169,-0.02332981,-0.018056953,-0.040565306,-1.359426415,-0.991610419,-2.266579055,-1.676915132,-2.57720711,-2.2200295580000002,-2.448902759,-2.087232285,0.29706764199999997,-0.8398327259999999,-8.602338284,-9.410581772,-9.463603912,-7.737253326,-7.335609337,-9.064643074,-7.83767217,-4.939334003,-1471.3607156258076 -3061,3061,A185G,-0.033608634,-0.023681149,-0.024861984,-0.045160985,-0.050523955,-0.011851243999999999,-0.047961102,-0.019256165,-0.040461599,-0.048215725,0.0008534269999999999,-0.023197419,-0.026526549,-0.047012735,-0.043309234,-0.04207960400000001,-0.058968306,1.4567241130000002,2.579772302,-5.233072729,-6.37270459,-6.846177483,-4.355751785,-3.826286987,-4.764442802,-5.8081828479999995,-1.137568871,-1465.9524949807674 -3062,3062,A185F,-0.06493873,-1.415873215,-2.236333583,-2.552280449,-2.844278657,-0.000787994,-0.02389632,-0.105981139,-0.074181464,-1.718448358,-1.113298071,-2.3915177919999997,-2.081149373,-2.048933333,-3.055627564,-2.7499327539999996,-2.938624559,0.087895735,-1.042675868,-10.71206912,-9.965279526,-11.06526134,-9.622275307,-9.313538132,-13.5939913,-7.98141515,-5.450003425,-1460.1359017468058 -3063,3063,A185I,-0.053221542999999996,-0.017483213,-0.03144166,-1.630652641,-2.6149388719999997,-0.080200214,-0.05212027599999999,-0.05432280900000001,-0.018175191,0.013743452,-0.048709878,-0.020952832,-0.041930487,-1.603422493,-1.6578827880000002,-2.9522393960000004,-2.277638347,0.46976688,0.686914982,-5.499524615,-4.631050873,-5.399659584,-4.525361,-5.512922477999999,-7.428629142999999,-6.190670562999999,-2.946994895,-1458.451023945585 -3064,3064,A185H,-0.026853823,-1.124137082,-2.2067250869999997,-2.5622625759999997,-3.069942666,0.000257749,-0.013227433,-0.040480212,-0.078561555,-1.249742114,-0.998532049,-2.263350085,-2.150100089,-2.397886881,-2.726638271,-2.700946294,-3.438939038,0.549557098,-0.756004179,-8.51190275,-8.380955963,-8.488374382,-7.780150856000001,-7.304434746,-10.6055978,-7.814952449,-5.529414251,-1464.9543133135885 -3065,3065,A185K,-0.044404121,-0.9674141409999999,-2.2243234590000003,-2.69690255,-3.172889151,-0.033649068,-0.039407315,-0.049400927000000004,0.076564537,-1.027973382,-0.906854899,-1.810187286,-2.638459631,-2.05386855,-3.33993655,-2.946753498,-3.3990248039999997,3.3291437760000004,1.293001436,-8.697672058,-8.854885094,-7.83964267,-7.523911064,-8.472442329,-10.79747913,-8.405112174,-5.710008152,-1461.5786105464213 -3066,3066,A185M,-0.037122277,0.01843216,-0.49366125899999996,-2.103042371,-2.9285139730000003,0.004858197,-0.02067364,-0.053570914000000004,0.052393595999999994,-0.02263114,0.059495459,-0.47207556700000003,-0.51524695,-2.02574167,-2.180343071,-2.471468586,-3.38555936,1.51617317,0.709779293,-6.6747547,-7.433013282999999,-7.203390739,-5.989738045,-6.417787186,-6.329844246,-6.1249469439999995,-2.839616983,-1456.8846146250144 -3067,3067,A185L,-0.050203683,-0.000365706,-1.1980125659999998,-2.240915612,-3.00665791,-0.030173362000000002,-0.043459405,-0.05694796,-0.032914345,-0.0035762520000000003,0.002844841,-1.247315677,-1.148709455,-2.195916279,-2.285914944,-2.927949934,-3.0853658860000004,0.867067265,0.106191403,-4.611370105,-4.678468521,-4.341564697,-3.8278066180000003,-5.005861122,-5.203149567,-3.730377582,-1.7326577580000002,-1463.264988140203 -3068,3068,A185N,-0.049408827999999995,-0.7295918090000001,-2.07579401,-2.857723933,-2.9736308819999997,-0.027906552999999997,-0.047644932,-0.051172722999999996,-0.03410538,-0.7538780959999999,-0.705305521,-2.183909482,-1.9676785380000001,-2.9716587910000003,-2.743789075,-2.542324444,-3.40493732,0.235418999,-0.576251362,-6.39444984,-7.081490517000001,-8.409150856,-5.3934461670000005,-5.575910835,-5.512250824,-5.721806907,-2.495635276,-1470.20020455122 -3069,3069,A185Q,-0.00943856,-0.564634195,-2.091161466,-2.3965136819999997,-2.9605459119999997,-0.071781564,-0.029400352999999997,0.010523234,0.035638584,-0.6239128420000001,-0.5053555470000001,-2.207759092,-1.974563839,-2.643325883,-2.14970148,-2.691112791,-3.229979033,0.5073210029999999,-0.506561001,-7.5476817370000004,-7.036175033999999,-6.932364204,-6.854644523999999,-7.496833801,-9.418391121,-7.101597588,-5.147896147,-1474.2330698412843 -3070,3070,A185P,-0.038933121,-1.028195166,-2.125714051,-2.448576657,-3.129075266,-0.011473812,-0.033977158,-0.043889084,-0.031293691,-1.163013578,-0.893376753,-2.1951049559999998,-2.056323145,-2.361826434,-2.535326879,-3.04643544,-3.2117150910000003,0.40872034799999996,-0.707009459,-10.02304055,-10.2672103,-10.45693192,-9.108223228,-9.039528069,-11.24330923,-10.00900564,-9.530625902,-1467.1917727896944 -3071,3071,A185S,-0.026151157999999997,0.006481436,0.0007910069999999999,-0.007999524000000001,-0.573427357,-0.007586402,-0.031590272,-0.020712043,-0.073491689,-0.006798891,0.019761763,-0.006987066,0.008569079,-0.044126062,0.028127015,-0.448140169,-0.698714545,1.145803503,1.6440050659999998,-3.3760563489999997,-3.721343674,-4.319970116,-2.883989937,-3.2290336610000003,-2.7259443589999997,-3.8512957969999997,-2.557189153,-1467.4133916599676 -3072,3072,A185R,-0.05009581900000001,-1.2825759890000001,-2.2017165569999997,-2.42638156,-2.414795069,0.080328571,-0.050202208,-0.049989429,-0.035764395,-1.454712028,-1.11043995,-2.1857734090000003,-2.217659705,-2.382458111,-2.470305008,-2.26543477,-2.564155368,0.070988724,-0.912108004,-6.397883322,-5.622271317,-5.301867157,-6.1007225720000005,-6.572227814,-8.392327751,-6.443756131000001,-4.894628797,-1462.8361335280351 -3073,3073,A185T,-0.020096463000000002,0.004536392,-0.056177994,-1.694488166,-2.386208396,-0.052809244000000005,-0.026372262999999996,-0.013820663,-0.019255994,-0.031485609,0.040558393,-0.078287711,-0.034068277,-1.6139845069999998,-1.774991824,-2.420178607,-2.352238184,0.8923665690000001,0.7077051540000001,-3.322105244,-3.646137421,-4.142583122,-2.257168938,-3.840589615,-2.724047127,-4.44948227,-1.362813681,-1461.2010940434411 -3074,3074,A185W,-0.00907795,-1.292192313,-2.252573029,-2.886261769,-2.8666353310000003,-0.033356176,-0.011605388000000001,-0.006550511,-0.038710903,-1.4113335759999999,-1.1730510490000001,-2.300002811,-2.205143247,-3.2126908569999997,-2.55983268,-2.9594477689999996,-2.773822893,0.27502411,-0.8824514240000001,-11.56765105,-11.57636394,-11.34360201,-10.78717826,-10.17638213,-13.95472892,-10.00900564,-9.53062648,-1462.3478661063127 -3075,3075,A185V,-0.065968972,0.008271694,0.0029441590000000004,-0.021148135,-1.607457871,0.018005252,-0.066515651,-0.06542229299999999,-0.046976620999999996,-0.002879092,0.019422479,0.036209932,-0.030321614,-0.036374049,-0.005922221,-1.446091781,-1.7688239609999998,0.718621735,1.325075583,-2.6568342069999997,-1.964291191,-1.653731812,-2.671388008,-3.0026322710000004,-3.9921277539999998,-3.5515066330000002,-1.019197891,-1462.5853382539935 -3076,3076,A185Y,-0.070438859,-1.39081188,-2.080228795,-2.2078003059999998,-3.131419231,-0.049347728,-0.082046765,-0.058830952,-0.0018746720000000002,-1.620451249,-1.161172511,-1.9043545990000001,-2.256102991,-2.361110689,-2.0544899219999997,-3.107867601,-3.1549708610000002,-0.085751977,-0.99298802,-11.55339915,-11.13989272,-12.30900917,-10.03907424,-9.062355415,-15.21666421,-8.032344806000001,-5.02162522,-1459.1706667314284 -3077,3077,T186A,-0.051869976,0.045460022,0.022103353,0.019967521999999998,0.049039139,0.006832653,-0.01862022,-0.08511973099999999,0.017509642,0.048129118,0.04279092599999999,0.029332632999999997,0.014874072,0.023740781000000002,0.016194263,0.010059428,0.08801885,1.174553362,2.599651906,0.484448805,0.822616997,0.671510292,1.017834297,-0.139738098,0.050020537999999996,-1.174869371,0.172016602,-1462.8476416780613 -3078,3078,T186C,-0.003947181,0.060716979000000004,0.021746003,0.049231988,0.066228188,0.03980164,0.045529917,-0.053424278,0.015723895,0.013609439,0.10782451800000001,0.061899265999999994,-0.01840726,-0.027223433999999998,0.125687409,-0.005087652,0.137544028,1.367594346,2.688442191,-3.574554997,-3.79519857,-3.751854324,-3.7905438769999997,-3.1352904660000003,-3.399887749,-4.85899242,-3.478068506,-1457.9175948472694 -3079,3079,T186E,-0.06642825599999999,0.083985966,-0.015274966000000001,0.050377795999999996,0.062168247999999995,0.014513931,-0.050886065999999994,-0.081970445,-0.008633107,0.164421845,0.003550087,0.067833651,-0.09838358300000001,0.10358921300000001,-0.002833622,0.11213737,0.012199126000000001,1.093728841,3.008726175,0.161197,-0.338675629,0.8142782140000001,0.752693924,-0.322283356,-0.100028152,-1.8520646809999999,-0.395577875,-1470.0715224640444 -3080,3080,T186D,-0.06338996200000001,0.09307471099999999,0.09015666300000001,0.029048848999999998,0.12718009800000002,-0.037177426,-0.07715901900000001,-0.049620905,0.02736536,0.10985126,0.076298162,0.108646558,0.071666767,0.121029369,-0.06293167200000001,0.16509674,0.089263455,1.047541235,3.116286293,-0.603712874,-1.476095177,0.5400757979999999,0.121780441,-1.443048759,-0.761276672,-2.480340976,-0.433399608,-1471.234121259302 -3081,3081,T186G,-0.034743433,0.057712495999999995,0.017675864,0.044081295,0.057716959000000005,0.034046834,0.0014475929999999998,-0.070934459,-0.015302373999999999,0.029192147,0.086232845,0.025864204,0.009487523000000001,0.024008242000000003,0.064154348,0.032459925,0.082973993,1.093682069,2.713746065,-0.345775545,-0.557374542,-0.501538811,-0.295958267,-0.559746277,0.185740173,-1.6769552380000001,-0.531908604,-1464.670210105367 -3082,3082,T186F,-0.072259767,0.032396121,0.009118899,0.037443919,0.038390943999999996,0.07914307,-0.0068332259999999995,-0.137686308,0.072399927,0.040463713,0.024328528999999998,0.015884527,0.002353271,0.069378073,0.005509765,0.038915632,0.037866255,1.211466628,2.8480288560000004,-4.271186082,-4.07816922,-5.119311714,-5.451313118,-3.2802368769999997,-3.426899483,-4.152174097,-3.135975113,-1457.4016781379469 -3083,3083,T186I,0.021356632,0.025422112,0.016256139,0.047038095,0.064125918,-0.02824627,0.053553192,-0.010839928,0.05087973900000001,-0.04188758,0.092731804,-0.101665393,0.134177671,-0.02838601,0.12246220000000001,-0.005916485,0.13416832,1.099551109,2.37430939,-3.5290195389999997,-3.627907455,-3.80451931,-4.358497581,-2.0174232030000003,-3.836750145,-5.146665032,-1.579001783,-1459.8146301610395 -3084,3084,T186H,-0.041207175,0.034109373,0.032269542000000005,0.013930268999999999,0.078777168,0.0051162479999999995,-0.010753137,-0.071661212,-0.001585156,0.0044660590000000005,0.063752687,0.024053316,0.040485767,0.015148377,0.012712161000000001,0.039483708,0.118070627,1.105856703,2.705501758,-1.052583203,-1.112644081,-1.151012047,-0.656309639,-1.018484474,-1.324465775,-2.1373509090000002,-1.478939884,-1460.229128159117 -3085,3085,T186K,-0.102015287,0.045586778,-0.013633771999999999,0.023359638999999998,0.063526439,0.088081481,-0.083129967,-0.120900607,-0.029071411000000002,0.089896255,0.0012772999999999999,0.011802103999999999,-0.039069648,0.037241899,0.009477379000000001,0.036437058,0.09061582,0.914327247,2.593112217,0.785576387,0.78230719,0.981446442,0.7102528459999999,0.9736326679999999,0.48024279,-0.213029154,-0.411428136,-1463.0837726555765 -3086,3086,T186M,0.000650066,0.02992557,0.056394089,0.043284625,0.079871209,-0.003534489,0.004061615,-0.0027614840000000002,0.026397969,-0.008897902,0.068749042,0.033328719,0.07945945900000001,0.055882826,0.030686422999999997,0.083128014,0.076614404,1.0658721709999999,2.817042518,-2.628861229,-2.314705551,-2.88108889,-3.7071386260000003,-1.49124218,-2.750130898,-3.583074401,-1.905964542,-1461.5115682347678 -3087,3087,T186L,-0.065299913,0.020081622,-0.006086841,0.03090952,0.04893101,0.027334715,-0.029106494,-0.10149333199999999,0.022704417,0.01896793,0.021195314,0.011792839,-0.023966521,0.053318427,0.008500613,0.056878482,0.040983538,1.075634088,2.7277795210000004,-2.104693701,-2.2884361269999998,-2.697402138,-2.920768181,-0.377654083,-2.239207977,-3.460971288,-0.5185029870000001,-1460.338148535695 -3088,3088,T186N,-0.071777942,0.05211263,0.08587661,0.061358267,0.079541488,-0.035514591,-0.059732470999999995,-0.083823413,-0.081263858,0.08801211099999999,0.016213149,0.162939704,0.008813516,0.132842612,-0.010126078,0.041183493,0.11789948300000001,1.054378671,2.949401794,-0.658452061,-1.3507616040000001,-0.100607605,-0.24848432199999998,-0.536696457,-1.05571032,-2.952713819,-1.01915564,-1465.0429005082697 -3089,3089,T186Q,-0.10242923,0.035523835,-0.034164405,0.025031605,0.070922127,0.048529296,-0.092377729,-0.112480731,0.031397836,0.095576858,-0.024529187999999997,0.029353077,-0.097681886,0.089860969,-0.039797759,0.111722482,0.030121772,1.172783769,3.065299393,0.544088359,0.503160233,0.9328265459999999,0.706571724,0.44226825700000005,0.135615036,-0.861570435,-0.502303855,-1467.2782614021562 -3090,3090,T186P,-0.067149865,0.015478685,-0.002556131,0.013835222,-0.979858789,0.0031999000000000003,-0.028449991,-0.10584973800000001,0.010703568,0.017749551000000002,0.013207818999999999,0.015638425,-0.020750687,0.016293195,0.011377248999999999,-0.7353775159999999,-1.224340061,0.8131363079999999,1.412826818,-5.644749071000001,-5.372252258,-5.516104812999999,-5.763138512,-5.723278572000001,-5.848971199,-7.398013917,-7.3489893660000005,-1460.9708959972486 -3091,3091,T186S,-0.052794932,0.024468739,0.008346544000000001,0.016023882,0.026542246000000002,0.046891017,-0.01644739,-0.08914247300000001,0.0018121020000000001,0.0039354609999999995,0.045002016,0.017271761,-0.000578673,0.009914256,0.022133507,-0.026285599,0.07937009,1.2222036059999999,2.4761450369999998,-0.071429585,0.034095657,0.287556595,0.043139015,-0.315808983,-0.406130211,-1.260373269,-0.78574134,-1463.6117782937363 -3092,3092,T186R,-0.073916062,0.041397571,0.043679866,0.022182927,0.06997376599999999,0.17823061399999998,-0.035176676000000004,-0.112655448,-0.119131797,0.009543161,0.073251981,0.066898503,0.020461228,-0.004364529,0.048730382,0.030740937000000003,0.109206594,1.191079577,2.647570344,0.592316081,0.820371002,0.7974291459999999,0.694061943,0.625207077,0.024511237999999998,-0.665725105,0.513679868,-1460.5523422118276 -3093,3093,T186W,-0.09062542900000001,-0.023354781,0.002000884,0.009366323000000001,0.043396619000000004,-0.046948307,-0.072996378,-0.108254479,-0.00713912,-0.065802754,0.019093193,0.009552085,-0.005550318,-0.001855962,0.020588608,0.039622217,0.04717102,1.177658364,2.682016338,-4.575853694,-4.181471771,-4.871396904,-4.8932327419999995,-4.359967758,-4.573199295,-4.890736925,-4.2068580010000005,-1455.546151552815 -3094,3094,T186V,-0.074503351,0.075607992,0.020407678999999998,0.061884914000000006,0.055647605999999995,-0.00881407,-0.055784109000000005,-0.09322259199999999,0.020132501,0.05816334099999999,0.09305264199999999,0.01586424,0.024951117999999998,0.04613934099999999,0.077630487,0.028994822000000003,0.082300389,1.043677402,2.540254647,-2.964307373,-3.1679438710000003,-2.988708252,-3.000943367,-2.301949387,-3.361991989,-4.53795547,-1.844081214,-1462.2628845497966 -3095,3095,T186Y,-0.10081969800000001,0.066725468,0.037632009,0.024546971,0.077859825,0.120519686,-0.047504385999999996,-0.15413501,0.026340678,0.025261854,0.10818908199999999,0.035209061,0.040054957,0.025928157,0.023165785,0.017049813,0.138669837,1.1680682009999999,2.634443941,-3.600423315,-2.916757423,-4.68752562,-4.620640617,-2.942760658,-2.8344322589999997,-4.964998369,-2.7725822730000003,-1453.6575686293654 -3096,3096,T187A,-0.00247782,0.039782501,-0.012975846000000001,-0.015191217,-0.499151566,0.021077328,-0.033023342000000004,0.028067703,0.019778847,0.069952977,0.009612024,0.014187423000000001,-0.040139115,0.007500955,-0.037883388999999996,-0.38263870899999997,-0.615664422,0.94998541,1.5898953830000002,-5.634194075,-4.914493683,-4.211839371,-8.131749725,-4.743877937,-6.169009658999999,-5.623722256000001,-1.641598925,-1452.3720085616224 -3097,3097,T187C,-0.071034633,0.001795653,-0.010014803000000001,-0.093694775,-0.854236268,0.010845488,-0.06866157099999999,-0.073407695,0.0049709490000000005,-0.009984221,0.013575526000000001,-0.00540218,-0.014627425,-0.143273954,-0.044115595,-0.646480163,-1.061992373,1.5832389059999998,1.7981661830000002,-9.353331291,-8.838002022000001,-11.00442151,-10.29617422,-9.367192528,-7.26086618,-6.83266191,-2.127619604,-1453.3419941724278 -3098,3098,T187E,-0.007346303,-0.023657092999999997,-0.06392933099999999,-1.530928188,-2.552683678,0.0036318170000000003,-0.076063279,0.061370673,0.071236613,-0.001711695,-0.04560249,-0.051017837,-0.076840824,-1.3625852790000001,-1.699271096,-2.476767615,-2.628599741,1.14938596,0.768007662,-12.44105987,-12.02727456,-12.56591955,-13.73394483,-11.56198572,-12.31617468,-10.52248242,-8.511017341,-1449.026613288559 -3099,3099,T187D,-0.10926971099999999,0.004138091,-0.038010397,-0.050844883,-0.08524659,-0.026128071,-0.13039948099999998,-0.088139941,0.05954527,0.065736493,-0.057460312,0.06976494,-0.145785734,0.043844296,-0.145534062,-0.017590605,-0.152902574,1.276624209,2.6737797530000003,-8.618710542,-8.200002617,-9.028312225,-9.45363208,-6.600597092,-9.811008698,-4.9164917589999995,-0.573999519,-1458.9039211906493 -3100,3100,T187G,0.005888361999999999,0.028210136,0.0055505780000000005,-0.016230803999999998,-0.6913414290000001,-0.008837448000000001,-0.040428542000000005,0.05220526599999999,0.05573892,0.06085368,-0.004433408,-0.000657488,0.011758643999999999,-0.006661135,-0.025800472,-0.519989185,-0.862693672,0.810773139,1.462812543,-8.435471208,-7.984572281,-8.507582932,-9.15159565,-7.404895226,-9.128709953,-6.18495103,-1.686280785,-1453.4724285090342 -3101,3101,T187F,-0.045404997999999995,0.07005750599999999,0.05448183400000001,-0.016548101000000003,-1.8229373309999999,0.116017292,-0.035963318,-0.054846677999999996,-0.014904866000000001,0.100321464,0.039793548,0.10129507300000001,0.007668595,-0.050750212,0.01765401,-1.549508596,-2.096366066,0.5469332410000001,1.311451869,-11.68199432,-8.817125267,-15.0091776,-11.23387903,-14.90722314,-8.442566559,-6.008612364,-1.136603201,-1448.6132681332529 -3102,3102,T187I,-0.087644625,0.06491658,-0.006978818,-0.013895846000000002,-0.578642539,0.04629445099999999,-0.095478441,-0.07981080900000001,0.018106997,0.139530144,-0.009696985,0.050453024000000006,-0.06441066,0.008609145,-0.036400837000000005,-0.34762532799999996,-0.80965975,1.958966849,2.392367641,-7.838811961,-6.309117737,-8.395758942,-9.45207238,-9.469714508,-5.56739624,-6.649019214,-0.9737358970000001,-1446.0374529431574 -3103,3103,T187H,-0.070539448,0.035037287,-0.004869834,-0.06388287299999999,-2.217539756,0.078425123,-0.050767100999999995,-0.090311795,0.039321055,0.08446519400000001,-0.01439062,0.014707427,-0.024447095,-0.034762106,-0.09300364,-1.87840377,-2.556675742,0.7338122579999999,1.303687588,-10.96309934,-10.60261366,-11.87996316,-11.45931833,-12.71336178,-8.160239792,-7.538904772,-3.995165884,-1448.3209805269726 -3104,3104,T187K,-0.164605587,-0.017233508,-0.76751297,-1.2202363859999998,-1.628477245,0.312785115,-0.165672651,-0.163538522,-0.19373753100000002,0.02780434,-0.06227135599999999,-0.8834916559999999,-0.6515342829999999,-1.42833731,-1.012135461,-2.1031869519999997,-1.1537675379999999,3.518192136,2.326351641,-12.34111129,-11.47459217,-13.63994494,-13.22905772,-11.66102549,-11.70093615,-10.52248242,-8.511017341,-1459.0253268373199 -3105,3105,T187M,-0.03789987,0.006222499,0.00339993,-0.079470755,-0.569884531,0.16085450699999998,0.0101835,-0.08598324,0.027327036000000002,0.061815072,-0.049370075,0.039191324,-0.032391465,-0.029909602999999996,-0.129031906,-0.451277649,-0.6884914120000001,0.9590630840000001,1.574091243,-7.102944997000001,-5.07657222,-8.514319336,-9.59433474,-7.230271889,-5.099226799,-6.205544515,-1.7752006340000002,-1451.6768902717158 -3106,3106,T187L,-0.014389416,0.050198374000000004,-0.0057828409999999995,-0.054315929000000006,-0.484891115,0.05040508900000001,-0.04410138,0.015322548,0.027864675,0.083755745,0.016641003,-0.018472331,0.00690665,-0.05842602400000001,-0.050205834000000005,-0.37079319299999997,-0.598989036,1.0808230559999998,1.662594168,-7.3370824720000005,-5.390972167999999,-9.141583481,-11.09317932,-6.736283051,-4.323394341,-5.621029696,1.004514833,-1444.223961376585 -3107,3107,T187N,0.146835362,0.067705494,0.030860622,0.04392771,-0.067171304,0.01446211,0.12653248,0.167138244,0.10173535199999999,-0.061136743,0.196547731,-0.101527436,0.163248679,-0.08995460699999999,0.177810026,-0.09348431,-0.040858297,1.486246105,2.372658463,-6.31453383,-5.43627301,-8.000293448999999,-7.456643173,-5.591130432000001,-5.088329086,-4.7259367910000005,-1.190166687,-1453.369290810544 -3108,3108,T187Q,-0.057097797,0.045594699,-0.011872908,-0.12052163699999999,-1.690890002,0.106282974,-0.091896611,-0.022298982000000002,0.024193715,0.080893827,0.01029557,-0.01926124,-0.004484575,-0.168101385,-0.072941888,-1.569949756,-1.8118302480000001,1.197762193,1.3667518419999998,-11.045627,-10.65344155,-11.32566238,-13.50242733,-10.0721,-9.674503716,-8.349604386000001,-5.174145708,-1448.4160653869621 -3109,3109,T187P,-0.0011750719999999999,-1.0509076290000001,-1.9507857219999998,-2.039223573,-2.552642805,-0.05313572900000001,-0.039772043,0.037421899,0.071267539,-1.2169520459999998,-0.884863211,-1.955434493,-1.94613695,-2.0198811819999998,-2.058565963,-2.67245443,-2.43283118,-0.12431906599999999,-0.752173615,-12.38872204,-11.650742300000001,-12.59283674,-13.80863772,-11.78758199,-12.10381147,-10.27555753,-7.5294009289999995,-1463.5415759403259 -3110,3110,T187S,-0.033943102999999995,0.040858867,-7.38e-05,-0.027495826,-0.072998047,-0.014013936999999999,-0.061315972,-0.006570234,0.068185862,0.078998424,0.00271931,0.003616989,-0.003764528,-0.007224626,-0.047767026,-0.030307517000000003,-0.115688576,1.264820319,2.529098747,-2.8905233310000003,-1.989547256,-3.829096619,-3.81862928,-2.182986305,-2.6323571930000003,-3.757538335,-0.36771381299999994,-1462.6076210071333 -3111,3111,T187R,-0.091547208,0.092933389,-0.854442922,-1.548821226,-1.94747267,0.37488457700000005,-0.095000715,-0.088093701,-0.117813686,0.15228741099999998,0.033579366,-0.7866649290000001,-0.9222209140000001,-1.429797124,-1.667845328,-1.8827980180000001,-2.012147321,3.6847991789999996,2.590349861,-12.58155176,-12.47559785,-12.19292096,-15.21236257,-12.16538672,-10.86149071,-10.48853256,-8.361566337000001,-1451.1807085899636 -3112,3112,T187W,-0.01087169,0.117279266,0.047987627000000005,-0.7692824559999999,-2.333350456,0.250103139,-0.021242057999999998,-0.000501321,-0.11328488800000001,0.161086237,0.07347229400000001,0.059920006,0.036055247,-0.45248970899999996,-1.086075203,-1.9501609969999998,-2.716539915,1.5990590530000002,1.379448433,-13.98684379,-12.33460432,-16.64228416,-13.98215629,-14.709030499999999,-12.26614365,-8.336045424,-4.891284924,-1449.7644018684514 -3113,3113,T187V,-0.023786055,0.023386524,-0.001549652,-0.034999675,-0.670291875,0.001823534,-0.054522199,0.0069500890000000004,0.057510723,0.031851847999999995,0.014921200000000003,0.009326257,-0.01242556,-0.032733637,-0.037265713,-0.47811161399999996,-0.862472136,1.152846942,1.6452441530000002,-7.383042337000001,-5.052011406,-7.0058119660000004,-8.829811539,-8.241655693,-7.785921082000001,-6.647229316000001,-1.533883139,-1451.625385953579 -3114,3114,T187Y,-0.048593952,0.135146638,-0.057504944,-1.500922422,-2.4306478190000003,0.252472354,-0.00845919,-0.088728713,0.001082879,0.156076697,0.114216579,-0.056365277000000005,-0.058644611,-1.171086238,-1.830758605,-2.447995873,-2.413299764,0.8825504000000001,0.754023055,-14.32132197,-13.32496182,-16.86227638,-13.29797762,-16.16295296,-11.95844106,-7.684766806,-2.7667683010000004,-1447.6577895060182 -3115,3115,L188A,-0.020518577,-0.052350189000000005,-0.05527152,-0.062904802,-1.20747049,-0.075153104,-0.046622712000000004,0.005585559,-0.0061199159999999996,-0.060093618,-0.044606759,-0.059171514,-0.051371525,-0.09271222400000001,-0.033097378999999996,-0.877754209,-1.537186771,1.175719652,1.485322417,-8.627420511,-8.663883156,-8.856683136000001,-8.760536392,-6.8990741810000005,-9.95692569,-6.195895843,-4.5716489110000005,-1463.5985434632748 -3116,3116,L188C,0.021918244,-0.052956088,-0.026166817999999998,-0.005878016999999999,-1.090092962,-0.096717444,0.019482641000000002,0.024353846000000002,-0.00494145,-0.121542452,0.015630276999999998,-0.045804252000000004,-0.006529383000000001,-0.059718766,0.047962733,-0.891695129,-1.288490795,0.9311351609999999,1.41377584,-10.08544011,-10.94043574,-9.791555687,-11.53817464,-9.051717506000001,-9.105316993999999,-7.458772022000001,-5.984954223,-1459.139151001349 -3117,3117,L188E,-0.022292077,-0.337516945,-1.580114639,-2.3959931340000002,-3.037699413,-0.070355423,-0.025349952000000002,-0.019234201,0.013105023,-0.24272991600000002,-0.43230397299999995,-1.500183244,-1.660046034,-2.3911109109999997,-2.400875357,-3.033144902,-3.0422539239999997,1.2242249920000001,0.098449606,-12.59703572,-12.99192192,-13.12778668,-12.95171986,-11.37201019,-12.54173992,-9.916627407,-10.2655079,-1461.8250371706672 -3118,3118,L188D,0.018427904,-0.725098006,-1.965789216,-2.222618055,-2.713809337,-0.116255625,0.000604229,0.036251579,0.066058042,-0.634352802,-0.81584321,-2.192836126,-1.738742305,-2.20870253,-2.23653358,-2.549706526,-2.877912147,0.562929814,-0.504970305,-12.94877676,-13.50833361,-13.31924121,-13.49938637,-11.54755515,-12.86936745,-9.916627407,-10.2655079,-1459.4779710294679 -3119,3119,L188G,0.004024969000000001,-0.027412995,-0.011802058,-1.4364275659999999,-2.153407982,-0.086507109,-0.010374028,0.018423966,0.01773789,-0.019159186,-0.035666803,-0.018737619,-0.004866496,-1.321027287,-1.551827844,-2.127481734,-2.17933423,0.774853537,0.725128787,-11.69772429,-12.84238483,-11.6938976,-12.25401973,-10.367368800000001,-11.33095048,-8.432711413,-6.6496991560000005,-1459.9640893321484 -3120,3120,L188F,-0.046343314000000004,-0.080928885,-0.10571058,-0.05404149,-0.129732593,-0.083994914,-0.0755392,-0.017147427,0.062353263,-0.074197938,-0.087659832,-0.06597600099999999,-0.145445159,-0.08463530400000001,-0.023447675,-0.10275339900000001,-0.156711786,1.364145129,2.229929175,-7.138384087,-7.616309631,-5.880091156000001,-9.047303154,-5.896759529,-7.251456963,-5.6083372879999995,-2.217248718,-1456.8335509011522 -3121,3121,L188I,0.021721432000000002,0.022037183,0.017778982,0.048551418,0.057770815,-0.152550278,0.019313402,0.024129462,0.071580379,0.09205545,-0.047981085,0.13687119,-0.10131322699999999,0.140659475,-0.043556639,0.130392401,-0.014850772,1.090017585,3.0145197789999996,-4.277052489,-4.38802327,-4.582082993,-4.833239021,-2.723001907,-4.858915253,-4.782911362,-3.160726838,-1459.3449881928973 -3122,3122,L188H,0.058826245,-0.055225607999999995,-0.017755378999999998,-1.662675485,-2.357136858,-0.098123852,0.057282176,0.060370314,-0.044102068,-0.026969915,-0.0834813,-0.005758246999999999,-0.029752511000000002,-1.643723491,-1.681627479,-2.160818746,-2.553454969,0.963682736,0.712865124,-11.74983114,-10.83752493,-11.60532037,-13.25999049,-10.777579699999999,-12.26874023,-8.058000501,-6.605246233,-1458.1416262569837 -3123,3123,L188K,-0.001801911,-0.644136855,-1.716633939,-2.274492774,-2.552699689,-0.140854673,-0.064246204,0.060642383,-0.096054253,-0.699078132,-0.589195578,-2.0467080909999997,-1.386559787,-2.36360449,-2.185381057,-2.40357849,-2.7018208880000003,1.608030166,-0.087844622,-12.45666786,-12.91355421,-12.84788934,-13.00431638,-10.77449552,-12.74308385,-9.916627407,-10.2655079,-1461.1508715925738 -3124,3124,L188M,0.030134035,0.037080838,0.02556723,0.031242474,0.013036622,0.173557643,0.028108512999999998,0.032159556,-0.011581777,0.065467926,0.008693749,0.017676482,0.033457978,0.01589654,0.046588408,0.017735036000000003,0.008338207,1.212035903,2.698347019,-3.8391984860000004,-3.504306038,-3.545502739,-4.986957878,-3.594585266,-3.5646405110000003,-3.579982452,-2.04499402,-1464.1494938312098 -3125,3125,L188N,0.076311861,0.079064491,-0.519759545,-1.7922252730000001,-2.2209471869999997,-0.29053747,0.050030263,0.102593459,-0.071102186,0.174533065,-0.016404084,-0.51779139,-0.5217276989999999,-1.948631142,-1.635819404,-1.988605142,-2.453289231,3.426463347,2.1907539519999997,-11.74352516,-12.58189905,-11.66700979,-12.91844707,-10.62159679,-10.92867307,-7.983485018,-6.731979184,-1457.1816232907586 -3126,3126,L188Q,0.002275617,-0.058223163,-0.323303452,-1.776922785,-2.796089769,-0.156741203,0.001982734,0.002568499,0.054664137,-0.06574181700000001,-0.050704507999999995,-0.33260261399999996,-0.31400429,-1.94112154,-1.61272403,-2.82619358,-2.765985958,1.409330674,0.7164802440000001,-11.87106411,-12.56353465,-12.18360018,-12.22432749,-10.23496996,-12.14888824,-9.871206654,-9.953681979,-1465.0931710884906 -3127,3127,L188P,-0.008176471999999999,-1.330026782,-2.184384119,-2.504880619,-2.85520948,-0.068645738,-0.033965316,0.017612372,0.063524615,-1.5868282519999999,-1.0732253109999998,-2.159686701,-2.209081536,-2.318975247,-2.69078599,-2.679284398,-3.031134562,-0.53150622,-1.018168713,-11.32190251,-11.66167559,-11.90596698,-12.19796056,-9.865851921,-10.97805747,-9.16732865,-8.426016059,-1465.286553727463 -3128,3128,L188S,0.030988929,-0.054324574,-0.048228195999999994,-0.200926457,-1.805171884,-0.162694057,0.00800728,0.053970577,0.01969241,-0.068205367,-0.040443781,-0.068000806,-0.028455585,-0.235134884,-0.16671803,-1.803739959,-1.806603809,1.253373888,1.34711866,-10.08657208,-10.71719389,-10.30387226,-11.6769986,-8.596399765,-9.138395905,-7.354691946,-5.144556167,-1457.6918325065635 -3129,3129,L188R,-0.006223495999999999,-1.365831231,-2.174752305,-2.536338651,-2.954465915,-0.093969237,-0.030050752000000003,0.01760376,0.054898559000000006,-1.595067779,-1.136594683,-2.227598233,-2.1219063769999997,-2.3226458819999998,-2.75003142,-2.760559891,-3.1483719389999996,-0.68783752,-1.025059173,-12.20531454,-12.96899566,-12.20203719,-12.636119,-10.76133637,-12.45808447,-9.916627407,-10.2655079,-1458.338315419387 -3130,3130,L188T,0.035537495,-0.034539709,-0.031612913,-0.033241597000000005,-0.29830189100000004,-0.048583855,0.046285312,0.024789677000000003,0.034205156,-0.025537945,-0.043541473,-0.042607992000000004,-0.020617833000000002,-0.059374487999999996,-0.007108705999999999,-0.267847774,-0.328756008,1.4599025630000002,2.069588987,-8.715158913,-8.939680237000001,-9.228401092999999,-9.245671318,-6.994047455,-9.167994461000001,-6.558231144,-4.640139284,-1457.7227217890322 -3131,3131,L188W,-0.005505665999999999,0.0010837169999999999,0.021869237000000003,-1.2381610090000001,-1.912952574,-0.106983638,-0.03930288,0.028291549,0.037691244,0.008379983,-0.00621255,0.017946902,0.025791571,-1.008889635,-1.467432382,-1.983362087,-1.842543061,2.25388802,1.567719347,-8.049796152,-7.6176235729999995,-7.997799614,-9.967349876,-6.905369385,-7.76083831,-6.204658488,-4.490488647,-1456.4047583672218 -3132,3132,L188V,0.021504185,-0.025040412,-0.046188727,-0.030946418,-0.081581387,-0.063368251,-0.025193864,0.068202234,0.007415074000000001,-0.0465887,-0.0034921229999999998,-0.073721825,-0.018655629,-0.098037803,0.036144968,-0.10239730400000001,-0.060765469,1.3617598480000002,2.235593191,-5.332364012,-5.543175827000001,-5.140654068,-5.789023201,-4.268513283,-5.920453682000001,-5.755182501,-2.9179900919999997,-1463.0984770008363 -3133,3133,L188Y,-0.058809655999999995,0.013988469,0.016992074,-0.024781799,-1.120273917,-0.046393262000000005,-0.112965698,-0.004653613,0.176668238,-0.01717766,0.045154598,0.052512005,-0.018527857,-0.050088782000000005,0.000525184,-0.8247483390000001,-1.415799494,0.766689025,1.3871123380000001,-9.338633989,-8.737391167,-7.995724747000001,-11.57245286,-8.770836037,-9.616765137,-4.969438372,-2.29874559,-1463.6066016899422 -3134,3134,R189A,0.022913215,-0.019845914,0.014606148000000001,-0.020606068,-0.017229056,-0.051370195,0.010717579,0.03510885,0.028612883999999998,-0.029198183,-0.010493644,0.032562334,-0.0033500390000000004,-0.033521329,-0.007690806,-0.009867948,-0.024590162999999998,1.323844396,2.642309041,-3.931520349,-4.95875351,-3.0290880889999996,-3.723505119,-3.328450974,-4.617804054,-4.923875324,-0.415841034,-1458.2832820527256 -3135,3135,R189C,0.078814877,0.0015941520000000002,0.020839035,0.012955113999999998,-0.003296714,-0.096298044,0.090781446,0.066848308,0.020112668,-0.027823237,0.031011541,0.013553262,0.028124807999999998,-0.017634155,0.043544383,-0.000220234,-0.006373194,1.1691247679999999,2.573707615,-8.228251372999999,-9.019602577,-8.184463356,-6.7973975520000005,-9.041738205,-8.098055176,-7.501274445,-4.73699917,-1455.2752475328743 -3136,3136,R189E,-0.0073795959999999996,0.000276437,-0.0009229039999999999,0.004874544000000001,-0.303910933,-0.078782972,-0.014978658999999998,0.00021946700000000002,0.076141275,-0.026325822000000002,0.026878696,-0.012173231000000001,0.010327423,0.017952239,-0.008203152,-0.247869118,-0.359952747,1.16112586,1.8608409719999999,-2.3188110180000003,-2.49918364,-2.254430847,-1.320054329,-3.5605466310000002,-1.959839645,-3.7062587939999996,-0.219645669,-1465.7688954053447 -3137,3137,R189D,-0.011796437,-0.056782793,-0.040873402,-0.039571741,-1.147991783,-0.134423248,-0.046501191,0.022908317,0.022928387999999997,-0.071921271,-0.041644314,-0.023698278,-0.058048525999999996,-0.08223111400000001,0.003087633,-0.786578036,-1.5094055290000001,1.021315688,1.452288201,-3.589498279,-3.22622287,-3.5285172730000003,-2.489105301,-4.577162003,-4.126483948,-4.4363656680000005,-1.875344046,-1467.1444477615878 -3138,3138,R189G,0.027454466,-0.011249161,0.005039355,-0.0032351690000000004,-0.047906629000000006,-0.083224907,0.017991669,0.036917262,0.029327327,-0.035870207,0.013371886000000001,0.019596231000000002,-0.009517521999999999,-0.019499416999999998,0.01302908,-0.052334860999999996,-0.043478397,1.3479277530000002,2.52259184,-3.647680479,-4.4452390369999994,-2.129972816,-4.136704422,-4.171114182,-3.355371941,-4.0960194130000005,-1.668978148,-1465.8227645955049 -3139,3139,R189F,0.057231551,0.034031176,0.068291801,0.028687159,0.034164252,-0.09430800199999999,0.030692161000000003,0.083770941,0.042186858,-0.0006721489999999999,0.06873450099999999,0.09515567300000001,0.041427927999999996,0.084024346,-0.026650029,0.04400315,0.024325354,1.107605496,2.785883252,-8.780333279,-10.46347237,-8.304324829,-6.398182082999999,-8.002809303,-10.73287782,-7.379134872000001,-4.604622404,-1455.5248275976628 -3140,3140,R189I,-0.012396398000000001,-0.0016488579999999998,-0.0369291,-0.001477996,-1.078739255,-0.083964217,-0.037666793999999997,0.012873998000000001,0.0067064559999999995,-0.034132711,0.030834995,-0.010018581,-0.063839619,-0.013159239,0.010203248,-0.8528192290000001,-1.30465928,0.630413013,1.369631712,-8.738645613,-10.87568135,-8.50214534,-7.223305679,-8.093512413,-8.998583282,-7.171284253,-3.275832991,-1455.4716603611596 -3141,3141,R189H,0.062862684,0.00376831,0.022097897000000002,-0.00076256,0.028994949,-0.089242473,0.052394487000000003,0.07333088,0.062336130999999996,0.004993428,0.002543191,0.02891534,0.015280453000000001,-0.012053987,0.010528866999999999,0.018319629,0.039670268,1.189076917,2.640709113,-1.28419646,-1.107344467,-1.593092239,-1.12446067,-0.683609589,-1.912475334,-2.536985322,-1.9920540780000002,-1462.4678310467862 -3142,3142,R189K,-0.014139725,-0.095491851,0.056788633,0.047192499000000006,0.043095827,-0.038630584,-0.040698343,0.012418894,-0.010063755,-0.041819538999999996,-0.14916416300000002,0.165698448,-0.052121183,0.068810425,0.025574573,0.130410561,-0.044218907,1.107384667,2.9304942339999998,-3.028105875,-3.971506363,-3.045740662,-2.451450752,-2.803053795,-2.868777802,-4.513367825,-0.745441358,-1462.3251850819215 -3143,3143,R189M,0.025213489,-0.035412455,-0.008399852,-0.01574027,0.023547909,0.010953735,0.003277383,0.047149595,0.103210938,-0.066014348,-0.004810562,0.027653874,-0.044453577,0.031946647,-0.063427187,0.08429917,-0.037203352,1.0834987409999999,2.851156773,-8.903250528,-10.10188995,-8.435840111000001,-7.52246656,-9.086401131,-9.369654884,-6.560797542,-4.072348863999999,-1456.0931568942033 -3144,3144,R189L,0.039392461000000004,-0.020381434,0.004636895,-0.013295572,-0.020162666,-0.11593555400000001,0.013405624,0.065379298,0.054046329000000004,-0.028537327,-0.01222554,0.009692174,-0.000418384,-0.035993594,0.009402451,-0.004823205,-0.035502126,0.978053416,2.399313709,-8.010846902,-9.612922928,-7.479939247000001,-6.44412664,-8.485814766,-8.031430931000001,-6.018101881000001,-2.5959728230000003,-1454.9054186320864 -3145,3145,R189N,0.047490995999999994,-0.023471844,0.025487403,-0.110464545,-0.151627343,-0.074115839,0.033495698,0.061486293,0.12970863900000001,-0.015007196,-0.031936491000000004,0.056528202,-0.005553397,-0.060123302999999996,-0.160805786,-0.211230015,-0.09202467,1.3815607030000001,2.056764385,-3.279822583,-3.1461555860000003,-4.47727977,-2.4937665630000003,-2.560272842,-3.7216381530000002,-4.196688943,-2.085489161,-1465.6489156484604 -3146,3146,R189Q,-0.007294685,-0.008469168000000001,0.016089434,0.006403879,-0.002750312,0.045376077,-0.013983229,-0.00060614,0.1833259,0.10443331199999999,-0.12137164800000001,0.104409615,-0.072230748,0.090523707,-0.07771595,0.035566676,-0.041067299,1.543610422,3.106887046,-1.239628874,-1.661118706,-1.1917691959999999,-0.303437935,-1.711987938,-1.329830597,-2.834561775,-0.505662056,-1467.5953868976794 -3147,3147,R189P,0.025602858,-0.026666004,-0.694758416,-1.840275487,-2.171437555,-0.078551041,0.022659277999999998,0.028546437,0.03696397,-0.044147067000000005,-0.00918494,-0.630869773,-0.7586470590000001,-1.9109861890000002,-1.769564785,-2.186467985,-2.156407125,3.080772019,1.80421002,-10.1447918,-10.98275433,-9.73491716,-9.564907532000001,-10.23873639,-10.20264357,-9.362421619,-8.092063116,-1465.0272109722719 -3148,3148,R189S,0.025602035,-0.037027944,-0.011408995,-0.029251264,-0.039930577,-0.079979839,0.020008243999999998,0.031195825,0.046147889000000004,-0.053011097,-0.02104479,-0.026802954,0.0039849640000000006,-0.070728498,0.01222597,-0.023401961000000002,-0.056459193,1.372052346,2.555496231,-4.382848163,-5.352790283,-3.6197654189999997,-4.23592218,-3.8962125089999997,-4.809550423,-4.770054274,-1.6184139180000001,-1462.2262422735803 -3149,3149,R189T,0.024339398999999998,-0.014084962,-0.031068516,-0.015227365,-0.14586111300000001,-0.092432266,0.016677793,0.032001004,0.029558103999999998,-0.020310003,-0.007859921,-0.033220341,-0.028916691,-0.051340929,0.0208862,-0.147006084,-0.144716141,1.446717983,2.2408187219999998,-5.305592595,-6.8947660829999995,-4.877355072,-4.841380341,-4.899679291,-5.014782188,-4.884648673,-1.586938534,-1457.9962967392057 -3150,3150,R189W,0.027951349,-0.048304976,0.021896105,-0.004475476,0.037155394,-0.033956169,0.03102118,0.024881517000000002,0.10126373300000001,-0.081443202,-0.01516675,0.052842872,-0.009050662,-0.067326212,0.05837526,-0.015034084,0.08934487099999999,1.160699455,2.310883681,-8.983569702,-9.129856041,-10.24698942,-7.15780481,-8.672057785,-9.711140457,-7.534908913,-5.4617895999999995,-1454.4192314068787 -3151,3151,R189V,0.017249786,-0.004532015,-0.021470896,-0.020956172,-0.162167656,-0.097538691,-0.000909202,0.035408774,0.097371881,-0.031276592,0.022212562,-0.024458642000000003,-0.018483149,-0.060147937,0.018235593,-0.15627320000000003,-0.16806211199999999,1.338312844,2.131367392,-7.680897582999999,-9.525529778,-7.750949768,-6.551226051,-7.29980954,-7.276972777999999,-7.286696524,-2.304073754,-1458.0930875684135 -3152,3152,R189Y,-0.005833714,-0.040701081,-0.06650236400000001,-0.058099121,-0.009767181,-0.080644685,-0.002289672,-0.009377756,-0.090665426,-0.105438385,0.024036224,-0.09091240800000001,-0.042092319,-0.089733841,-0.0264644,-0.025884032999999997,0.006349672,1.311321958,2.476381603,-5.440068082000001,-5.60817038,-5.616003227,-3.742688858,-4.940997696,-7.2924802479999995,-5.0504218430000005,-2.842339122,-1451.4439931879751 -3153,3153,K190A,0.051136055,0.018567251,0.046552289000000004,0.114627695,0.131802291,-0.07971932400000001,0.075854083,0.026418026,0.165095875,0.041679545,-0.004545044,0.071827673,0.021276905,0.169760503,0.059494887,0.248097525,0.015507056000000002,0.999647928,3.1242593039999997,-2.626431894,-1.599060783,-3.3776943360000002,-3.3926156689999996,-2.597986038,-2.1648026430000002,-2.8779261689999998,0.052349634000000006,-1460.7728028763086 -3154,3154,K190C,0.070959461,0.016238781,0.021940961000000002,0.08909844800000001,0.09068624199999999,-0.116190815,0.043757902,0.098161019,0.10760317400000001,0.027743767000000003,0.004733794,0.026721788,0.017160134,0.162300391,0.015896504,0.207180058,-0.025807575,0.957748142,2.90986283,-7.221659456,-6.842708954,-7.566843177999999,-7.711919303999999,-7.469255187999999,-6.517570656,-6.9852702529999995,-4.819136913,-1455.6963963615708 -3155,3155,K190E,0.058327508,0.037203692999999996,0.027473486000000002,0.138486931,0.154985174,-0.021730812000000002,0.050453477999999996,0.066201538,0.020038848999999997,0.072504025,0.00190336,0.035176847000000004,0.019770124,0.20378294,0.07319092099999999,0.28630921800000003,0.023661129,1.193443681,3.2232906000000003,-2.66321443,-2.384031586,-3.4178030930000003,-3.306620918,-2.100569275,-2.107047279,-3.30078447,-1.676094159,-1457.6554423146881 -3156,3156,K190D,0.029619665,0.018094706000000002,0.002788744,0.084752212,0.100962865,-0.030071496,0.09007196699999999,-0.030832637000000003,0.084320886,0.022055194,0.014134218,-0.003960665,0.009538152,0.073222895,0.096281528,0.15889493300000002,0.043030797,1.075612453,3.070360491,-4.047834096,-3.358297592,-4.196962395,-4.632644722,-4.360793472,-3.690472298,-4.55623057,-2.611198743,-1454.8079157005996 -3157,3157,K190G,0.083653955,0.0036218179999999997,0.012560166999999999,0.115267979,0.077161286,-0.061159062,0.080157845,0.087150064,0.11928410099999999,0.0039265409999999995,0.003317094,0.008079678,0.017040656,0.14099088,0.08954507800000001,0.15708878699999998,-0.0027662159999999997,1.234188512,3.071937563,-3.954357947,-3.668315971,-3.3878134380000002,-5.207447662,-4.053275703,-3.4549369580000002,-4.17547608,-1.854062425,-1461.0630438500084 -3158,3158,K190F,0.026829027000000002,-0.12065612,-0.051680839000000006,0.022996747999999997,-0.217008299,-0.082375449,0.06905210099999999,-0.015394047,0.303822896,-0.156337366,-0.084974873,-0.015602527,-0.08775915,0.078721355,-0.032727859,-0.040411595,-0.39360500200000004,1.270488892,2.533330658,-7.097180214,-7.2713716129999995,-6.931698272999999,-8.425394798,-7.124956749,-5.732479637000001,-6.209571041,-4.184823022,-1455.2314306106418 -3159,3159,K190I,0.08282801299999999,0.02723384,-0.018771113,0.122197355,0.108124379,-0.10018500699999999,0.094393409,0.071262617,-0.062147907,0.060944062,-0.006476381999999999,0.0037918270000000002,-0.041334052999999996,0.207848848,0.036545862,0.200889968,0.01535879,0.967372558,3.056630347,-5.944695491,-5.871439789,-6.525079903,-6.842501671,-5.4228471979999995,-5.061608894,-5.772740852999999,-2.567488527,-1455.58991784323 -3160,3160,K190H,0.049684448,0.017389238,0.0038171840000000004,0.073260169,0.113907221,-0.034282122000000005,0.08664414699999999,0.012724748999999999,0.12690832900000001,-0.024579186,0.059357661,-0.020588703,0.028223071000000002,0.109778631,0.036741707,0.12409977900000001,0.103714662,1.134830888,2.999257431,-2.976281262,-3.352399399,-3.63552626,-3.5012896039999997,-2.9671871189999997,-1.425003929,-4.103015946,-2.385403038,-1455.4558879407123 -3161,3161,K190M,0.08332503,-0.006246636999999999,-0.035846314,0.044839563,0.06426857,-0.050357398,0.101536085,0.065113974,-0.075112884,-0.044110595,0.031617321000000004,-0.101677481,0.029984853,0.051754217000000005,0.037924908,0.079340564,0.049196575,1.0578344370000001,2.853788227,-5.124878133,-5.2751310810000005,-5.129668716,-6.2079474789999995,-4.888170845,-4.123472542,-4.722812889,-1.617101485,-1456.2327222651802 -3162,3162,K190L,0.062068255999999995,0.036144497000000005,0.0337272,0.110483771,0.09924628,-0.121457433,0.082031517,0.04210499400000001,0.108941825,0.024758912999999997,0.04753008,0.039286632,0.028167768,0.162424627,0.058542914,0.16838051699999998,0.030112042000000002,1.08321687,3.161940692,-4.357624245,-4.189187859,-4.041275627,-5.749778305,-4.630841866,-3.1770375669999997,-4.785073097,-0.8048507420000001,-1454.6534781353548 -3163,3163,K190N,0.077588054,-0.007869114,-0.021035625,0.17126141399999997,0.11623518699999999,-0.078748344,0.09588434800000001,0.059291759000000006,0.034762106,0.020319748999999998,-0.036057976,-0.023380445,-0.018690804,0.17507975899999997,0.167443068,0.140003345,0.092467028,1.098635386,3.12187274,-1.255120435,-1.722629776,-1.229730743,-1.2073258059999998,-0.798408813,-1.3175070340000001,-2.432203271,-2.219738678,-1458.6813572291285 -3164,3164,K190Q,-0.033031008,0.023736287999999998,0.02468798,0.16130820699999998,0.17701405,-0.050846062000000004,-0.05854237,-0.007519645,0.092224103,0.085106939,-0.037634364,0.12610642,-0.07673046,0.26923816100000003,0.053378252,0.288040144,0.065987956,1.33142065,3.565361933,-1.656487144,-1.828385056,-2.2336580809999997,-1.897497978,-1.060336876,-1.262557732,-1.82075844,-1.449972561,-1459.475502976682 -3165,3165,K190P,0.04875832099999999,0.027105125,-0.030132237000000003,-1.54116656,-2.16444907,-0.09460010199999999,0.07719275,0.020323891,0.138727575,-0.0061799540000000005,0.060390204,-0.057393027,-0.0028714459999999997,-1.457132799,-1.62520032,-2.112064997,-2.216833143,0.829209801,0.717584806,-9.035988582,-8.657854446,-9.435519875,-9.506569382,-9.162935905,-8.417063301,-8.816291035,-8.695880952000001,-1459.6046503353864 -3166,3166,K190S,0.052101355999999995,0.012444461,0.017023187,0.08815933199999999,0.101368661,-0.09184786199999999,0.05254718,0.051655532000000004,0.159105511,-0.005563883,0.030452805,-0.008870550999999999,0.042916924,0.09430656800000001,0.082012095,0.146532306,0.056205016,1.055509506,2.96653421,-3.1934224330000003,-2.949397385,-3.739954025,-3.81310479,-3.00731398,-2.457341988,-3.602818258,-1.930497076,-1458.682201151736 -3167,3167,K190R,0.059388287000000005,0.034166915,0.027263827999999997,0.121003326,0.134726194,-0.026695691,0.085517604,0.033258969,0.112030158,0.026808794,0.041525036,0.046364432000000004,0.008163223,0.142171569,0.099835083,0.209778827,0.05967356099999999,1.024261699,3.1672944610000004,-1.339058783,-1.237130653,-1.498608902,-1.7063660580000002,-1.629141991,-0.62404631,-2.5121490019999997,-0.134337415,-1453.2945738816634 -3168,3168,K190T,0.031442154,0.019029975,0.0029206809999999996,0.09249076099999999,0.142137028,-0.121792833,0.025171078,0.03771323,0.162248032,0.017023252,0.021036698,0.00745841,-0.0016170479999999998,0.150109471,0.03487205,0.237646215,0.046627840999999996,1.160203223,3.253758487,-1.9769778669999998,-1.508473595,-2.504234955,-2.388802971,-1.4770856780000001,-2.006292137,-3.063114498,-1.452826613,-1459.849568283651 -3169,3169,K190W,0.06670215,2.0600000000000003e-05,-0.013984795,0.089247088,-0.205482836,-0.068286923,0.090452611,0.042951687999999995,0.09058856,-0.002043236,0.002084397,-0.050690436,0.022720846,0.107116412,0.07137776400000001,-0.083540765,-0.327424906,1.155297011,2.294729223,-6.899035202,-7.1532381670000005,-6.930895485,-7.452406792000001,-7.105028824,-5.853606742999999,-6.824246284,-3.986297685,-1452.9039518786594 -3170,3170,K190V,0.110414599,0.027055392,0.029952699,0.11070142300000001,0.094288889,-0.087925831,0.099816793,0.121012405,0.17095161899999997,0.015919797,0.038190986,0.011041583,0.048863815,0.151427513,0.069975333,0.172975308,0.01560247,1.016875373,2.950497949,-5.661271236,-5.219789673,-6.2214621889999995,-6.379913826,-5.394115349,-5.091075142,-5.1719610430000005,-2.85580433,-1458.4151280205697 -3171,3171,K190Y,0.035999566000000004,0.067232282,0.047060162,0.083534659,0.11072970300000001,-0.026863687999999997,0.051406285,0.020592847,0.261262869,0.090837581,0.043626982,0.131171136,-0.037050812999999995,0.125649867,0.04141945,0.215373681,0.006085725,0.9624281170000001,3.0170886739999996,-5.767462352000001,-5.644081009,-6.642833617999999,-6.668387169,-6.0342227479999995,-3.8477872160000004,-5.165993341,-3.4220268010000003,-1453.7094764537178 -3172,3172,L191A,-0.059776188,0.005842155999999999,0.00585183,-0.073817836,-1.740208362,-0.032925196000000004,-0.033920126,-0.08563225,-0.021483526,0.025795575,-0.014111263,0.047756335,-0.036052675,-0.047840545,-0.099795126,-1.70812149,-1.772295234,0.6660483460000001,1.31034536,-5.839957387,-6.999184265,-5.0009273069999995,-4.159628098,-7.287010048,-5.753037216,-5.88403837,-3.532099293,-1461.175587898586 -3173,3173,L191C,0.018012068,0.064766801,0.053803178,0.040816542000000004,-1.540306586,-0.024951217,0.081573971,-0.045549835999999996,0.084121055,0.046687225,0.082846377,0.030213795,0.07739256,0.014999944,0.06663313900000001,-1.199666891,-1.880946281,0.6833676609999999,1.336175506,-8.519051564,-9.012254379,-7.562880447,-8.25594664,-9.109028976,-8.655147377,-7.982534082000001,-6.1619902,-1461.7445421763696 -3174,3174,L191E,-0.043555289000000004,-0.01730507,-0.6125044270000001,-1.9028242219999998,-3.091910494,-0.05386553400000001,-0.052802555,-0.034308022,-0.028454746,-0.039201473,0.004591334,-0.469107389,-0.755901465,-1.80467654,-2.000971903,-2.9564617739999997,-3.227359214,1.65663859,0.799096426,-10.67940588,-11.12017895,-9.824424095,-9.851792038,-12.21956138,-10.38107295,-10.35567423,-10.06195992,-1458.0955468676984 -3175,3175,L191D,-0.038911075,-0.732807909,-1.933339784,-1.881349089,-2.706935997,-0.0031844720000000003,-0.016557443999999998,-0.061264705,0.10760592599999999,-0.7328934109999999,-0.7327224059999999,-2.144666753,-1.7220128140000002,-1.49458493,-2.268113248,-2.521431427,-2.892440567,3.7390675769999997,1.7683123280000002,-10.82870968,-11.1525738,-10.25715211,-10.19130738,-11.79012745,-10.75238766,-10.35567423,-10.06195978,-1458.4084672695026 -3176,3176,L191G,-0.017561478000000002,-0.029738274,-1.184604464,-2.059512668,-2.8190958999999998,-0.058443017,-0.020674798,-0.014448157,0.012760616,-0.02402161,-0.035454937,-1.29368819,-1.075520737,-2.140236863,-1.978788473,-2.667099222,-2.971092577,0.689531227,0.09432728,-10.57089603,-11.39756277,-9.565598671,-9.668758163,-11.86182362,-10.36073695,-10.35567423,-10.06195812,-1459.1650705980137 -3177,3177,L191F,-0.043325475999999995,-0.064916196,-0.004016675,-0.018522592,-0.063981014,-0.058554392999999996,-0.09235262,0.005701668000000001,-0.053447004000000006,-0.114845314,-0.014987078000000001,-0.022174274,0.014140925,-0.016566351,-0.020478832,-0.106827017,-0.021135011000000002,1.246280512,2.180128282,-5.103042503,-5.235241013,-4.748483673,-5.931625809,-5.02568882,-4.574173203,-5.222541644,-1.549945493,-1454.12502432568 -3178,3178,L191I,0.062241091,-0.033821056,0.030783902000000002,0.026537917999999997,-0.075122951,0.05837182,0.06214767400000001,0.062334508,-0.044021890999999994,-0.128856029,0.061213917,-0.016329038,0.07789684200000001,-0.021593857999999997,0.074669693,-0.087826664,-0.062419237,1.3710261030000002,2.356899824,-3.2084544569999998,-2.789797478,-2.9461277010000004,-2.6135253069999997,-3.739199188,-3.9536226119999998,-4.308825097,-0.724836335,-1454.489995116368 -3179,3179,L191H,-0.05895876,-0.05676943,-0.032335669,-1.225496,-2.35386511,-0.042467661,-0.04998487,-0.067932649,0.011748596000000002,-0.065858853,-0.047680006,0.012794526,-0.07746586400000001,-1.006870602,-1.444121397,-2.3034894009999998,-2.4042408180000003,1.998396659,1.339675274,-11.17417525,-11.32139128,-10.139121800000002,-11.01269725,-12.23473479,-11.16293111,-10.15137662,-9.151812278,-1454.9915686580352 -3180,3180,L191K,0.034661124,-0.210727357,-1.3249637090000002,-2.368774727,-2.566725383,-0.011719908999999999,0.029421245,0.039901003,-0.061680320999999996,-0.299710498,-0.121744215,-1.40167992,-1.248247498,-2.103780615,-2.633768839,-2.477414598,-2.656036167,2.912919216,1.266880981,-10.47715518,-10.96264593,-9.726199883,-9.895066138999999,-11.21703923,-10.584824699999999,-10.35567423,-10.06195785,-1458.2772142845206 -3181,3181,L191M,0.046768924,-0.003572198,0.041040194,0.07359428400000001,0.010860928999999998,0.052049754000000004,0.0054540890000000005,0.08808375800000001,0.04639667,-0.067989733,0.060845337,-0.002641821,0.084722209,0.019781593,0.127406974,-0.0016698720000000002,0.02339173,1.306832352,2.660187788,-4.574158328,-5.0967700119999995,-3.992778328,-4.996237892,-5.238987679,-3.546017731,-5.604151706000001,-2.8964312139999997,-1457.1340650347993 -3182,3182,L191N,-0.016918433,-0.000398916,-0.46031679700000006,-1.793718647,-2.564733321,-0.049028709000000004,-0.028787383,-0.005049482,-0.005281826,-0.047898525,0.047100694000000005,-0.39272507700000003,-0.5279085170000001,-1.5419838030000002,-2.045453491,-2.459685831,-2.66978081,1.748137847,0.9113450999999999,-10.54702189,-10.84608856,-9.396377975,-10.31425221,-11.77760453,-10.40078619,-10.35567423,-10.06196007,-1465.234544168692 -3183,3183,L191Q,-0.040736725,-0.025382305,-0.031031258,-1.20523162,-2.104050617,-0.025114123,-0.044604074,-0.036869375,-0.010878397,-0.046066829000000004,-0.004697781,-0.048641649,-0.013420866000000002,-1.114183375,-1.296279865,-2.8302400389999995,-1.377861194,0.767103489,0.7435716309999999,-8.919233947999999,-9.653577683,-7.878621773,-8.363665382,-9.763488113,-8.936816788,-8.91511272,-6.890620775,-1459.0066228173673 -3184,3184,L191P,-0.025812619,-1.076675827,-2.06903566,-2.227364915,-2.918265711,-0.040128255,-0.009972771,-0.041652467,0.07170044,-1.203099562,-0.950252091,-2.147511487,-1.990559832,-2.262615937,-2.192113892,-2.787517595,-3.0490138260000004,0.262499949,-0.7299549209999999,-10.66117895,-11.29977943,-10.10428368,-9.779856575,-11.6346221,-10.48735298,-10.33976853,-9.987470731,-1461.7605700809509 -3185,3185,L191S,-0.016333601,-0.01827237,0.010130785,-1.662707776,-2.314900941,-0.067036207,-0.005211839,-0.027455362,0.005748683,-0.048884437999999995,0.012339698999999999,0.031340243,-0.011078673999999998,-1.6758773830000002,-1.6495381690000002,-2.48087513,-2.148926751,0.588944459,0.685853919,-8.272700656,-9.025064835,-7.5166185,-7.289787987,-9.716501274,-7.815530685,-8.297106203,-5.796244727,-1457.4471003562212 -3186,3186,L191R,-0.032735981000000004,-1.127532557,-2.153819295,-2.2801936730000003,-2.845487107,-0.033077311,-0.013476613,-0.051995348,0.053713819,-1.26097335,-0.994091763,-2.054599881,-2.253038708,-2.099123257,-2.461264089,-2.773787235,-2.917186978,0.121637977,-0.759073797,-10.62409386,-10.94906579,-9.847023047999999,-10.09692328,-11.19254352,-11.03491365,-10.33780824,-9.942447565,-1457.7544686426409 -3187,3187,L191T,0.024844332,0.005427876,0.014034733,-0.042890211,-1.584024862,-0.03320954,0.04248524,0.0072034230000000005,-0.010171906999999999,-0.05720374599999999,0.068059497,-0.016246636999999998,0.044316102,-0.09322763,0.007447208,-1.662351264,-1.505698459,0.8761677609999999,1.323265973,-6.647715549,-6.820422272,-6.73479493,-4.781570465,-8.226654114,-6.675135963,-6.911223132000001,-4.560065386000001,-1462.3547332393937 -3188,3188,L191W,-0.017274081,0.015300961,0.03019861,-0.22060888399999998,-1.7520991419999998,0.24234797800000002,-0.010026577,-0.024521585,-0.181851106,-0.066270215,0.096872137,-0.023723085,0.084120305,-0.276193423,-0.16502434400000002,-1.7162966869999998,-1.7879015969999998,1.3859966869999998,1.378507776,-9.900976346,-9.978946297,-9.373570457000001,-9.707945427,-10.2954249,-10.14899465,-9.144344099,-7.448499955,-1452.0160094718449 -3189,3189,L191V,-0.038041103,0.019414397,0.01213088,0.042499229000000006,-0.31300932600000003,0.001180688,-0.064818154,-0.011264051,-0.012127708999999999,0.04407792,-0.005249126,0.076282177,-0.052020417,0.08105931799999999,0.00393914,-0.210515925,-0.415502727,1.139131189,1.913296832,-4.36171153,-4.713060577,-4.103531609,-2.94987989,-5.03966436,-5.002421211000001,-5.043673885,-1.640404854,-1462.197346570436 -3190,3190,L191Y,0.0039196,0.009608831,-0.013623645,-0.011806981999999999,-1.555942535,-0.046269527000000005,-0.010525861999999999,0.018365061000000002,0.027798256,0.005545795,0.013671866000000001,0.010500528,-0.037747817,-0.031055986,0.0074420219999999995,-1.418293146,-1.6935919240000001,0.675699114,1.321324272,-7.892167682,-8.037979385,-7.679999176,-8.026649223,-8.446566978,-7.2696436460000005,-6.896882594,-2.739769986,-1449.5025664786808 -3191,3191,L192A,-0.030093041,-0.018597648,0.004566675,-0.032185099,-1.556554077,0.00413323,-0.015503578999999998,-0.044682502,0.003284755,-0.043783456,0.00658816,0.008439791,0.000693559,-0.041853207,-0.02251699,-1.447693105,-1.6654150490000001,0.66379259,1.319291736,-4.72954753,-4.137270439,-3.5724570539999996,-6.561465111,-5.062589958,-4.313955086,-4.777098457,-0.202280221,-1465.8010918255895 -3192,3192,L192C,-0.072189961,-0.06074313,-0.017870328,-0.061819434000000006,-1.063779785,-0.009946776,-0.053528125,-0.090851796,0.0031686490000000004,-0.0027215359999999997,-0.118764723,-0.049487579000000004,0.013746923999999999,-0.072777275,-0.050861593,-0.728730691,-1.398828879,1.134913898,1.514565605,-7.789434381,-6.730953293,-6.716847015,-9.172089432,-7.562688057000001,-8.764594108999999,-7.11180867,-3.9591517560000002,-1460.3287188769318 -3193,3193,L192E,-0.016312019,-0.005492534,-1.192431906,-2.261885403,-2.8290247560000004,-0.14821705,-0.023575416000000002,-0.009048622,-0.059880141,-0.022731462,0.011746393999999999,-1.292486789,-1.092377023,-1.980997907,-2.542772899,-2.945806655,-2.712242856,2.4618966159999998,1.000907241,-9.666221663,-8.421228149,-9.187280212000001,-9.836956131,-10.048214699999999,-10.83742912,-7.739932646000001,-2.360981195,-1471.1975105339661 -3194,3194,L192D,-0.0977562,-0.7465218159999999,-1.9299711819999998,-2.302637077,-2.832883323,0.024337091,-0.073482813,-0.122029587,0.013568469,-0.71316072,-0.779882911,-1.835068031,-2.024874332,-1.9953053719999998,-2.6099687819999997,-2.534145388,-3.131621257,3.166304976,1.2488567959999999,-10.32483852,-8.985172951000001,-10.55701305,-11.21356181,-9.843146423,-11.02529835,-7.0842839710000005,-1.9369325880000001,-1471.181535395328 -3195,3195,L192G,-0.02054542,-0.018021733999999998,-0.269382432,-1.97212395,-2.784570413,-0.048436697,0.00196303,-0.043053869,0.025664535,-0.033830449,-0.002213019,-0.220885761,-0.31787910199999997,-2.0327677630000003,-1.911480136,-2.884536999,-2.6846038269999997,1.160947692,0.672098558,-8.995588751,-8.422604247999999,-7.772801163,-9.96720742,-8.737161385,-10.07816954,-6.544715929,-2.8661006710000003,-1469.7738289358094 -3196,3196,L192F,0.018059132,0.013732505,0.081264467,0.052959093,-0.042845814,0.008473507,-0.035597165,0.071715429,-0.081348484,0.02380942,0.0036555890000000003,0.12046073300000001,0.042068201,0.054372465,0.051545720999999996,-0.025444519,-0.06024710900000001,1.1765857709999998,2.5441896880000003,-4.061002045,-3.9903556669999998,-3.315355515,-4.827034035,-3.990668472,-4.181596535,-5.177439804,-1.89699271,-1465.932159142103 -3197,3197,L192I,-0.069777974,-0.001081698,0.027459208,-0.077981889,-0.063610451,0.090775706,-0.024977776,-0.11457817199999999,-0.027931268,0.009687722,-0.011851118,0.07105025400000001,-0.016131839,-0.05060818,-0.10535559800000001,-0.042905532999999996,-0.084315368,1.293262937,2.444541636,-3.2540302339999996,-2.763771927,-3.42018129,-3.976919296,-2.7916781160000004,-3.31760054,-4.181987799,-2.110439195,-1463.9298275448382 -3198,3198,L192H,0.002827638,-0.021074957000000002,0.018251937,-1.081000003,-1.7914210069999998,-0.068898464,0.030313309,-0.024658034,0.029338594,-0.037038927,-0.005110986,0.016572451000000002,0.019931422,-1.017581766,-1.14441824,-1.880932874,-1.70190914,2.482627962,1.777334189,-9.941204733,-9.223816299,-9.009222076,-9.995435608,-9.023766274,-12.45378341,-6.2548152870000004,-1.906427831,-1470.1578670106828 -3199,3199,L192K,-0.011885218999999999,-0.082585491,-1.293341385,-2.342098539,-2.784299155,-0.01344116,0.052918327,-0.076688764,-0.006815572,-0.054553174,-0.11061780800000001,-1.244646347,-1.342036422,-2.279944951,-2.404252127,-2.642693709,-2.925904601,0.69323654,0.082934906,-10.83902905,-8.775747437,-11.56617721,-10.44357752,-9.262011498,-14.14763158,-7.387362891,-2.888252352,-1468.6631439365447 -3200,3200,L192M,0.020424973,-0.035529635,0.050145005,0.012442773,-0.01111662,-0.076911852,0.039294164,0.001555781,0.00020821200000000002,-0.016899802,-0.054159467999999995,0.110139794,-0.009849785,0.015649866000000002,0.00923568,-0.002237326,-0.019995913,1.190825765,2.6261859430000003,-4.326503384,-3.801950821,-3.993620064,-4.8600371860000005,-4.138020561,-4.83888829,-5.642897883,-3.136287209,-1465.6520477887243 -3201,3201,L192N,-0.066510789,-0.068928879,-0.53117053,-1.98860017,-2.853349806,-0.08928135,-0.049294769,-0.083726809,0.042282662,-0.102189123,-0.035668635,-0.51817757,-0.54416349,-1.8756954680000002,-2.101504871,-2.715565481,-2.9911341310000004,1.739102434,0.796762298,-10.15522688,-8.819087142999999,-8.484116142000001,-11.26751642,-9.557899368,-12.64751531,-7.595864006,-2.240495693,-1469.9213801259175 -3202,3202,L192Q,-0.035816492000000005,-0.030334247,-0.008216564,-1.556737045,-1.901721304,-0.07225350700000001,-0.037717294,-0.033915689,-0.030206312000000003,-0.06574239700000001,0.005073904000000001,-0.029419805,0.012986677,-1.306928441,-1.806545649,-2.000670417,-1.80277219,2.310706123,1.519088042,-8.99955246,-8.512910271,-8.233344154,-9.799404082999999,-8.140600395,-10.3115034,-6.495590624,-2.3725815409999997,-1474.0098807732575 -3203,3203,L192P,-0.076151972,-1.194151849,-2.355943961,-2.675004871,-2.830189854,-0.055266875,-0.04983382099999999,-0.102470122,0.073053756,-1.329194622,-1.059109075,-2.320333653,-2.3915542690000002,-2.5774810059999997,-2.772528735,-2.9402297639999997,-2.720149943,-0.177793423,-0.829006213,-11.16924901,-10.16042255,-10.51537383,-12.06715256,-11.27947244,-11.82382368,-9.693537361,-6.3019651770000005,-1465.2744393227622 -3204,3204,L192S,-0.052541483,-0.007488388,-0.024562893,-0.8683095009999999,-2.098896634,-0.061763032,-0.020935118,-0.08414784800000001,0.018634248,-0.008444171,-0.006532605,-0.033722657,-0.015403129,-0.645945248,-1.090673754,-1.888023554,-2.309769713,1.880949767,1.466201925,-7.370516104,-6.953204765,-5.970887466000001,-8.942981926,-7.358421989,-7.627084373,-6.249580821,-2.322293918,-1467.5348292635754 -3205,3205,L192R,-0.069107056,-0.61776422,-2.09799211,-2.295990668,-3.061556477,-0.024888612,-0.037694169,-0.10051994199999999,0.062532852,-0.631930701,-0.603597739,-2.1664185469999997,-2.029565673,-2.069091586,-2.522889749,-2.7105939439999998,-3.41251901,0.621005751,-0.48666955,-9.847440504,-8.514317322,-8.736329132,-10.07694566,-8.260961822999999,-13.64864859,-7.016678992,-1.9257547069999998,-1467.3140904777683 -3206,3206,L192T,-0.042714469000000005,0.029272092000000003,0.051726372,0.0017215289999999999,-0.833308562,0.039246727,-0.020944903,-0.06448403400000001,-0.014532755,0.045462563,0.01308162,0.09725369800000001,0.006199046,0.02872325,-0.025280193,-0.5657714770000001,-1.100845647,0.572736437,1.394288648,-4.708355646,-4.498802757,-3.6362300419999998,-5.809624222,-5.306235611,-4.290885597,-4.083399228999999,-1.048326915,-1469.7578137638047 -3207,3207,L192W,-0.015367998999999999,-0.040580889,-0.023038293999999997,-0.037028146,-0.9446483179999999,-0.06831121,-0.026788362000000003,-0.003947635,0.014168918999999999,-0.061084042000000005,-0.020077736000000002,-0.032498512,-0.013578075,-0.067797115,-0.006259176,-0.737824818,-1.1514718179999999,1.096908765,1.496590095,-8.171825443,-8.033199554,-7.596383865,-9.367173676,-8.492406487,-7.369963631,-6.534484337,-0.637565123,-1463.7638954659924 -3208,3208,L192V,-0.031325134,0.001978786,0.008643689,-0.048912497,-0.100550592,0.07946466099999999,-0.0158382,-0.046812068,-0.071795844,-0.043648560999999995,0.047606132999999995,-0.007948019,0.025235396,-0.071658636,-0.026166357,-0.14899316,-0.052108024,1.319928794,2.123259174,-2.641447591,-2.5141302640000003,-2.4048544240000003,-3.715702827,-2.972101662,-1.600448776,-3.4963505269999997,-0.256577214,-1466.2541437176988 -3209,3209,L192Y,-0.039728946,-0.0056144969999999995,0.031101041,-0.08741346800000001,-0.9478789259999999,-0.046987919,-0.030339538,-0.049118354,0.016018683,-0.034816721,0.023587728,0.05613717,0.0060649119999999996,-0.07168661,-0.103140325,-0.61651699,-1.279240861,1.136762899,1.562806313,-7.131275522999999,-5.95050705,-6.110677017,-8.04159523,-6.361701309,-9.191897011,-7.686589269,-0.18923414600000002,-1471.4417705559172 -3210,3210,T193A,-0.082039368,-0.02523072,0.017990193,-0.006502541,-0.014179751,-0.0028811609999999997,-0.018739441000000003,-0.145339294,-0.002449966,-0.023528021,-0.026933419,0.057729772,-0.021749386000000002,0.009600964,-0.022606046,-0.014632793,-0.013726708999999998,1.153378849,2.522290216,-2.773426036,-2.385111595,-2.8695091169999998,-2.99589859,-2.8797227860000003,-2.736888092,-4.639915959,-1.060856275,-1466.4640183402225 -3211,3211,T193C,0.029402227000000003,-0.019284908,0.03207698,0.007130841999999999,-0.007992230999999999,0.015254233999999998,0.012275295,0.046529158,0.007272092,-0.019070741000000002,-0.019499075,0.05770244,0.006451519,0.037942613,-0.02368093,-0.026652302000000003,0.01066784,1.325933007,2.691545222,-5.063013963,-3.949146378,-4.784970345,-5.136539536,-5.806743256,-5.637670302999999,-6.148862697999999,-3.250565728,-1463.9379943255335 -3212,3212,T193E,-0.023697577999999997,-0.055027854,-0.045130407000000004,-0.029274082000000003,-0.209827896,-0.043163081,-0.042359872,-0.005035284,0.017125616,-0.09717698,-0.012878728,-0.077667595,-0.012593218,-0.050609824000000005,-0.007938339,-0.18958702300000002,-0.23006876899999998,1.495163424,2.213152233,-4.171435013,-3.467381966,-2.554351204,-4.81175209,-3.983860245,-6.039829559,-6.205675985,-0.329497743,-1461.3930221525952 -3213,3213,T193D,0.024874887000000002,0.039178288,0.010549181000000001,-0.003289274,-0.07094539,0.021931107000000002,0.033009825,0.016739949,-0.041528328999999996,-0.0025124329999999997,0.080869009,-0.016066732,0.037165093999999996,-0.005794643,-0.000783904,-0.06001254,-0.08187824,1.31205633,2.46737095,-3.901440347,-3.329843719,-2.8426941219999997,-4.179172867,-3.19577494,-5.959716087,-5.1069804780000005,-1.030134113,-1460.7671460970305 -3214,3214,T193G,-0.010004476,-0.011059813,0.011663547,0.006739095,-0.038139974,-0.02345974,-0.021558552,0.001549601,0.007643478,-0.018125782,-0.003993844,0.02785773,-0.004530637,0.033839078,-0.020360889,-0.024483611000000002,-0.051796337000000005,1.235117378,2.449877744,-5.124488888999999,-3.270665428,-4.647929672,-4.9260777739999995,-5.86345639,-6.914315178,-6.454675852,-2.34542645,-1468.71210953407 -3215,3215,T193F,0.018152858,0.006275395,0.014265679,0.013289842,-0.019831781,-0.059170982000000004,-0.027460948,0.063766664,-0.021507539,-0.015958228999999997,0.028509019,-0.041749787000000003,0.070281144,-0.003261345,0.029841028,-0.024150746,-0.015512815,1.2999896229999999,2.6560617509999997,-2.302392981,-0.709044991,-3.0647665710000003,-1.794213799,-3.722325615,-2.22161393,-2.7461979469999998,-1.068535993,-1466.8108171676286 -3216,3216,T193I,-0.045105803,-0.057146867000000004,0.004338608,-4.3e-05,0.000771803,0.035180269,-0.061599348,-0.028612257999999998,0.009497771,-0.069804403,-0.04448933,0.040886827,-0.032209611,0.007684384,-0.007770463000000001,-0.021015332,0.022558937999999997,1.1778150809999999,2.492669546,-4.641043091,-3.3319243469999997,-4.720671089,-4.6573733289999995,-6.032173302,-4.463073387,-5.182928878,-2.231033751,-1466.5863844193518 -3217,3217,T193H,0.025222996,0.012286865,0.068564979,0.05574968,0.024926095,0.13755857400000002,0.018276304,0.032169687999999995,-0.095103875,-0.0076505359999999994,0.032224265,0.077501195,0.059628763,0.078900156,0.032599203,0.004337792,0.045514397000000005,1.208790157,2.8077500160000004,-4.775592317,-4.0236988369999995,-3.9696038060000003,-5.330397858,-4.566403076,-5.987858009,-6.069661391,-1.831544373,-1464.5727686937898 -3218,3218,T193K,-0.006335289,0.09892026699999999,0.089801819,0.066860645,0.098222012,0.36645111,0.009616214,-0.022286792000000003,-0.06848412,0.101877737,0.095962796,0.105249115,0.074354522,0.048063546,0.08565774400000001,0.08067965,0.115764374,0.981517427,2.801542944,-5.683566974,-6.175537642999999,-4.604824837,-7.470636803,-4.529606063999999,-5.637229522999999,-5.92706598,-0.536928298,-1464.3488642233424 -3219,3219,T193M,-0.033217487999999996,-0.014407732,0.00513787,0.006329894,0.031074253,-0.020824796,-0.077436671,0.011001695,-0.044062977999999996,-0.006522567,-0.022292896,0.081380775,-0.071105036,0.020231088,-0.007571301,0.10466757,-0.042519064,1.036897089,2.81709095,-5.021203539,-3.6143913189999997,-5.383386429,-5.535293114,-6.237929855,-4.335016975,-5.399916452,-2.778858837,-1468.1567446594127 -3220,3220,T193L,-0.022657796,-0.018740701999999998,-0.007353933000000001,-0.006878583000000001,-0.064364734,0.024469712,-0.027412379,-0.017903211999999998,-0.013162262,-0.03006112,-0.007420283000000001,0.003273709,-0.017981574,0.01914718,-0.032904346,-0.065370369,-0.063359099,1.3716330419999998,2.396912066,-2.07346852,-0.44138317899999996,-2.569027695,-2.236837074,-4.187376343,-0.932718307,-3.451524286,0.9717049609999999,-1468.36002250202 -3221,3221,T193N,-0.08169658,-0.013329423,-0.019257936,-0.004464028,-0.070475732,0.03457842,-0.09425275,-0.069140409,0.021555052999999998,0.025592764,-0.05225161,0.016586093,-0.055101964,0.053419968,-0.062348024,-0.016298115,-0.12465334800000001,1.160328634,2.481424064,-3.9112312999999994,-4.097652222,-2.672217751,-4.1821021730000005,-3.953627472,-4.650556885,-5.014979316,-0.527588009,-1466.1659731916152 -3222,3222,T193Q,-0.021139368,-0.029135496,0.023303557000000003,0.000580929,-0.027736966000000002,0.034558165,-0.017545183,-0.024733553,-0.046314035,-0.0051394629999999995,-0.053131528,0.048164766,-0.001557653,0.037978298,-0.03681644,0.026575887000000003,-0.08204981900000001,1.671448915,3.643209181,-5.069660439,-4.0801274869999995,-3.277920692,-6.922854645,-5.414491172999999,-5.652908196,-5.717092732999999,-0.409503591,-1467.6358061963692 -3223,3223,T193P,-0.032785098,-0.213288802,-1.554578691,-2.239535951,-2.585087471,-0.024102722000000004,-0.039672021,-0.025898174,-0.01313174,-0.18022422,-0.24635338399999998,-1.639689955,-1.469467426,-2.125558605,-2.3535132969999997,-2.524456566,-2.645718375,1.13366769,0.047235331,-7.54152103,-6.706070007,-6.908504607999999,-7.586830704,-8.14035009,-8.365849739,-7.933194762,-4.263459388,-1464.8638150743209 -3224,3224,T193S,-0.029120728,-0.014000674,0.016574138999999998,0.003528032,-0.042009722,-0.010574072,-0.043985055,-0.014256399999999999,-0.0068051480000000004,-0.023588772999999997,-0.004412575,0.013257611,0.019890666,0.02647941,-0.019423347,-0.048175943,-0.0358435,1.3011755790000001,2.468360252,-2.382935455,-2.210181595,-1.6847976000000002,-2.034777039,-2.902885033,-3.082036011,-4.604777259,-1.052631108,-1466.1115531218238 -3225,3225,T193R,-0.036439898,0.039386964,0.077011459,0.041274339,0.040937953,0.256052041,-0.039807487,-0.033072309,-0.135897621,0.034197495,0.044576432,0.08780204900000001,0.066220869,0.065123174,0.017425503000000002,0.029881907000000003,0.051993999000000006,1.125678591,2.743463773,-5.362511148,-4.083679039,-3.675248428,-7.771865524,-4.763572418,-6.5181903310000004,-5.53081505,0.24490160600000002,-1464.6336855106056 -3226,3226,T193W,-0.026055837000000002,-0.04065817,-0.010479853,-0.021555078999999998,-0.030497122,-0.001091514,-0.028382404,-0.023729269,0.001054612,-0.05800012400000001,-0.023316216,0.000707638,-0.021667343999999998,-0.018693103,-0.024417055,-0.029908081,-0.031086162,1.2929429959999998,2.54436965,-6.196283296,-4.455610435,-6.386380569,-6.391801086,-6.408609711,-7.339014679,-7.1820117329999995,-4.485218426,-1468.1008711038157 -3227,3227,T193V,-0.04590588599999999,-0.025494443,-0.000233005,-0.0110451,-0.000500627,0.011385969,-0.051169875999999996,-0.040641895,-0.0043209220000000005,-0.046723269000000005,-0.004265616,-0.009972449,0.00950644,0.00870964,-0.030799839,-0.016586339,0.015585086000000001,1.223862287,2.535234418,-3.0344193280000002,-2.040671104,-2.8969100269999997,-2.717678429,-4.5836535419999995,-2.93318354,-4.767009638,-0.723279789,-1467.2780845714733 -3228,3228,T193Y,0.020231434,-0.059274043,0.0050051359999999994,0.004253916,-0.049908680999999996,0.033477743,0.015343986,0.025118881000000003,-0.077321639,-0.094206865,-0.024341221,0.007409041,0.00260123,-0.0070694569999999995,0.015577288,-0.074172918,-0.025644444,1.1746679279999999,2.206485219,-4.293355396,-2.2545566790000002,-4.5705214000000005,-4.20582045,-4.883592163,-5.552286285,-5.552407122000001,-2.249611685,-1466.5102106919512 -3229,3229,G194A,0.008782263,0.017356052,0.001437804,-0.012425522,-0.033181736,0.031924606,0.0010896319999999999,0.016474893,0.0027201509999999996,0.018591418999999998,0.016120685,0.025930665,-0.023055058,-0.021452562999999997,-0.00339848,-0.046788955,-0.019574516,1.223670094,2.457657378,-4.855669742,-4.202727653999999,-4.273010025,-5.703035385,-4.547327591,-5.552248055,-4.3804917560000005,-3.9668406330000003,-1459.6133042974398 -3230,3230,G194C,-0.074171029,0.011931723,-0.012310443,-0.034681491,-0.14188896,0.043011468,-0.057019955,-0.091322103,0.022280808,-0.00199276,0.025856205,-0.007328091,-0.017292795,-0.031635864,-0.037727118,-0.134606817,-0.149171102,1.32564484,2.165305591,-7.750245682,-6.64422699,-6.748844246,-8.586031586,-7.260525574,-9.511600013999999,-6.490268288999999,-4.680526254,-1460.0740057541989 -3231,3231,G194E,0.014516342,0.027503057,0.000281661,-0.003042425,-0.00654365,-0.025249902999999997,0.013672338999999999,0.015360344,0.013882435,0.013940988,0.041065125,-0.035487314,0.036050635,-0.035043554,0.028958704,-0.03922821,0.02614091,1.4295704969999998,2.571178546,-3.39613277,-2.88639978,-3.0340473180000003,-4.509987373,-2.280352936,-4.269876442,-3.1798755560000003,-2.87586185,-1454.9879063577391 -3232,3232,G194D,-0.004154446,0.00844115,-0.017152778,-0.004588643,0.011114738,0.036840527000000005,-0.025085967,0.016777075,0.07682809,0.00493224,0.011950058999999999,-0.018223326,-0.01608223,-0.030369739,0.021192452999999997,-0.002955513,0.025184988999999998,1.22503257,2.5635841040000003,-3.9803161389999997,-2.8177548289999996,-3.53740799,-5.061411415,-3.3159220960000004,-5.169084366,-4.376996685,-2.004404139,-1455.4657963737845 -3233,3233,G194F,-0.041750885,0.013272291,0.014122516000000002,-0.020603002,-0.689851161,0.070116993,-0.042452593,-0.041049176,0.029349052999999996,0.002237664,0.024306917999999997,0.004469867,0.023775163999999998,-0.018695451000000002,-0.022510552000000003,-0.558466227,-0.8212360940000001,0.9918457490000001,1.516484973,-10.38313808,-8.193981972000001,-9.264329849,-11.9670813,-11.03188213,-11.45841513,-7.09898903,-4.684497614,-1461.3344668913633 -3234,3234,G194I,0.019379544,0.028645282999999997,-0.0033255740000000004,-0.07924677299999999,-1.6789258969999998,0.007397693,0.011286953999999998,0.027472134,0.042378516,0.013476965,0.043813599999999994,-0.036874309,0.030223161000000002,-0.12597006300000002,-0.032523483,-1.6001630009999999,-1.757688793,0.861362858,1.325403081,-9.791129358,-8.898473358,-8.588000015,-10.38325981,-9.269397881,-11.81651572,-8.697470726,-7.718834949,-1462.061916842591 -3235,3235,G194H,-0.035300038,0.030389773,0.027950977999999998,0.005488016,-0.086449922,0.280133591,-0.0029787290000000003,-0.067621346,-0.19904201300000002,0.053026338,0.007753207,0.032131887000000005,0.023770068,0.0027086370000000003,0.008267394,-0.102732166,-0.070167677,1.077306775,2.05380246,-7.5419094179999995,-6.143261702999999,-6.343967796,-8.444393462999999,-7.0160319289999995,-9.761892197,-6.2378627820000005,-3.304987086,-1455.21525314264 -3236,3236,G194K,0.046313707,0.08788367300000001,0.085578121,0.018087963999999998,-0.08905312,0.27229856399999997,0.066494864,0.026132548999999998,-0.054457035,0.101891759,0.073875586,0.09687471,0.074281532,-0.048123713,0.08429964,-0.123657196,-0.054449042999999996,1.519375409,2.391715016,-4.919286517,-4.248100273,-4.181224144,-6.2812802660000004,-4.3137239460000005,-5.572103958,-4.972720914,-2.835766182,-1452.9574424005114 -3237,3237,G194M,-0.011401651,-0.002285493,-0.037325911,-0.010949585,-0.109029557,-0.024610685,-0.005294691999999999,-0.01750861,0.02215354,-0.006998699000000001,0.0024277129999999997,-0.005600646999999999,-0.069051174,-0.055622646,0.033723477,-0.10941084400000001,-0.108648269,1.45268838,2.314535329,-10.09625978,-9.033632256,-8.907912735,-11.07793341,-9.514082275,-11.94773823,-8.501595032,-7.709841927,-1460.4681409187615 -3238,3238,G194L,-0.00046727,0.023047439,0.017005463000000002,0.009155372,-0.735460234,0.016973981000000003,0.01114606,-0.0120806,0.046643308,0.038563269,0.007531609,0.041870827,-0.007859900999999999,-0.0062911,0.024601843999999998,-0.491825368,-0.979095099,0.40102240299999997,1.37432973,-8.890255872000001,-7.802645409,-7.983619331,-9.829518494,-8.159678397999999,-10.67581773,-7.014479061,-5.5642483160000005,-1458.0100184809417 -3239,3239,G194N,-0.000720232,0.033825713,-0.004738975,0.015689355,-0.09927140699999999,0.070350346,0.025423651000000002,-0.026864113999999998,0.055741825,0.034879804,0.032771621,0.034015901,-0.04349385099999999,0.011301694,0.020077015,-0.094221186,-0.10432162800000001,1.514168428,2.4565161769999997,-5.34141469,-4.150462212,-4.380742111,-6.999095779,-4.567073227,-6.609700118999999,-5.11638179,-2.76677789,-1458.4923647260293 -3240,3240,G194Q,-0.04434509,0.008402235,-0.009199908,-0.013222728000000001,-0.031244143999999998,0.034588445,-0.07046425099999999,-0.018225928,0.000797913,0.039416122000000005,-0.022611652000000003,0.016759347,-0.035159162,-0.022176141,-0.004269314000000001,-0.039640001,-0.022848286000000002,1.3900470409999999,2.5568970230000003,-5.439480342,-4.8042290119999995,-4.693183952,-6.353939789,-4.449954689,-6.896094269,-5.221197789,-3.6808132039999997,-1455.64085820131 -3241,3241,G194P,-0.007224916,0.005813494000000001,0.001807947,-0.013510316999999999,-0.198504302,-0.006181981,-0.018387812,0.00393798,0.022548848,0.00800095,0.003626037,0.014756261000000001,-0.011140367,-0.010639677,-0.016380956000000002,-0.16454734099999999,-0.232461263,1.3030431690000002,2.096507555,-7.099125357,-5.930844521,-5.064448067,-7.986045555,-7.661919333999999,-8.852369308,-6.304047142000001,-3.246495168,-1456.064146054443 -3242,3242,G194S,0.011767131,0.031855577,0.007260607,-0.00582411,-0.004549414,-0.0041583,0.012399873,0.011134389,0.025487838,0.028807457,0.034903696,0.028269878,-0.013748663999999999,-0.010312018000000001,-0.001336202,-5.7999999999999994e-05,-0.009040828,1.3001260479999999,2.6362872040000003,-3.972095921,-2.8547378230000002,-3.281643616,-4.961868523,-3.350341995,-5.41188765,-2.6772010440000003,-3.339469533,-1458.0941348178312 -3243,3243,G194R,-0.0773031,0.082218584,0.067644808,0.015580974,-0.30361416,0.400175459,-0.021685912,-0.132920287,-0.16558842699999998,0.096712282,0.067724885,0.08393966900000001,0.051349945999999994,0.004491825,0.026670122,-0.234183127,-0.373045193,1.279592586,2.0161324730000003,-6.05877892,-4.992234131,-4.79722142,-7.083854492,-5.735860069,-7.684724487,-5.690167497999999,-3.093343664,-1453.7619909550995 -3244,3244,G194T,-0.023260199,-0.0064554109999999994,-0.014290415,-0.014268669,0.015216881000000002,-0.022587613,-0.042398318,-0.004122079,0.033666173,0.012739801,-0.025650622,-0.005106729,-0.023474101,-0.009905254,-0.018632084,0.005605748000000001,0.024828013,1.117138758,2.534675568,-4.533199487,-3.59620768,-3.9893631739999997,-5.329018539,-3.534232414,-6.217175629,-4.12106268,-4.181370737,-1454.8437014846131 -3245,3245,G194W,-0.009014715,0.005530593,0.025723607000000002,-0.019923878,-1.17832734,0.073097183,0.009595603000000001,-0.027625032999999997,0.014104877,0.026574602000000003,-0.015513416,0.045897108,0.005550106,-0.033537506,-0.00631025,-0.9302599359999999,-1.426394744,0.704758656,1.3616793530000002,-11.46661965,-9.903906768999999,-9.717849205,-12.64815269,-11.88463908,-13.17855051,-9.423639202,-9.985203535,-1462.4517933628522 -3246,3246,G194V,-0.018017463,-0.010651925,0.00215504,-0.043235019000000006,-1.411238447,0.051010722,-0.00814613,-0.027888796,-0.0029772740000000002,-0.015966756000000002,-0.0053370940000000006,-0.026750619,0.031060699,-0.086958652,0.000488615,-1.3747719440000001,-1.447704949,1.0510493090000002,1.367314041,-8.869816852000001,-8.299149002,-7.826587402,-9.489960915,-8.154504349,-10.57888259,-8.042026568999999,-6.940368032,-1459.762704711873 -3247,3247,G194Y,-0.008314896,0.025333123,0.032637452000000004,0.016243457,-0.707677085,0.005577294,-0.038945744,0.022315953,0.016295174,0.038082751,0.012583493999999999,0.069178164,-0.00390326,0.02045074,0.012036173,-0.377634266,-1.037719903,0.68022161,1.4905069219999998,-11.03783929,-9.262908928,-10.29203453,-11.89285094,-11.34127741,-12.40012464,-7.383035812999999,-5.86816079,-1461.5925085092895 -3248,3248,E195A,-0.04038856,0.033053773,0.054837576,0.048389688,-0.10781960800000001,0.214954758,-0.030259147000000004,-0.050517972,-0.13355383699999998,0.033375983,0.032731562,0.062891376,0.046783776,0.049993592,0.046785784000000004,-0.09308146199999999,-0.122557754,1.167460555,2.19751461,-2.434342494,-2.068805191,-2.57202771,-1.4018918759999999,-3.0401554180000003,-3.088832275,-4.2066898980000005,-1.677416777,-1461.255848520901 -3249,3249,E195C,-0.163197019,0.012843383,0.012837211999999999,0.004601143,-0.25358973100000004,0.450957528,-0.141687053,-0.184706985,-0.24113799100000002,0.09824425199999999,-0.07255748599999999,0.062943653,-0.037269229,0.031891573,-0.022689287000000002,-0.21537487100000002,-0.291804591,1.12933429,1.896195736,-5.346389555,-4.869292145,-6.046939125,-4.527680519,-5.7471240770000005,-5.540911911,-6.617596878,-4.502375504,-1463.8192868670449 -3250,3250,E195D,-0.038450162999999996,0.043654578,-0.034573946,0.042486805999999995,0.014874203,0.048300569,-0.042333592,-0.034566732999999995,-0.008037309,0.016242106,0.07106704900000001,0.015519003,-0.084666895,0.07425376,0.010719851,0.017147607,0.012600799,1.27185811,2.7498258360000003,0.487344681,1.5155127259999999,0.340776825,1.046860062,0.057464607,-0.523890816,-2.013093556,0.374354773,-1459.6987172779627 -3251,3251,E195G,-0.012313756,0.015974408,-0.002192625,0.029745906000000003,-0.014822188,-0.007474051999999999,0.003180947,-0.027808457999999998,-0.028329887999999998,0.009281787,0.022667028,0.011502431,-0.01588768,0.037391389,0.022100422,-0.010988253,-0.018656122,1.0610303220000001,2.4652918390000003,-1.346216862,-0.608883347,-1.8224222030000001,-0.260312088,-0.831826172,-3.207640503,-2.8495938869999997,-1.59431066,-1450.6256524766795 -3252,3252,E195F,-0.433225795,-0.466364546,-0.483548364,-0.799417851,-1.257844668,0.645962689,-0.541345186,-0.32510640399999996,-0.132234863,-0.557189722,-0.37553937,-0.393655935,-0.573440792,-0.952462612,-0.646373089,-1.0642742,-1.451415135,3.60254646,3.082991877,-7.06187328,-6.766275215,-7.785464531000001,-5.79806916,-7.46172477,-7.497832726,-7.954126447,-6.380862934,-1468.2793013919145 -3253,3253,E195I,0.435539185,0.073226077,-0.33915059399999997,-0.203475087,-0.923341277,0.296172559,0.5078728370000001,0.36320553200000005,-0.071040402,-0.080068467,0.226520621,-0.393655935,-0.284645253,-0.35040262,-0.05654755400000001,-0.763244204,-1.08343835,2.57133054,2.492226977,-6.495813696,-5.696652977,-6.842241341,-5.642756126,-6.711057831000001,-7.586360207,-7.298311657,-5.667384348,-1466.1686634300277 -3254,3254,E195H,0.020034141000000002,0.059504329,0.048392099,0.054972658,0.041473636,0.054948933,0.036076572,0.003991709,-0.079482198,0.049466021,0.069542637,0.054820139000000004,0.041964059000000005,0.070921207,0.039024107999999995,0.036682636,0.046264635,1.090498317,2.811500526,-2.76107944,-1.707558334,-3.6987059560000004,-1.841142448,-2.906142487,-3.651847977,-4.3541613869999996,-2.540602906,-1460.7568116150796 -3255,3255,E195K,0.022640048,0.04188953,0.040246296,0.016746623999999998,-0.015181175,0.247029473,0.043274702000000005,0.002005393,-0.134580943,-0.028236828999999998,0.11201588800000001,-0.05598580000000001,0.136478392,-0.019103668,0.052596915,-0.078575811,0.048213461,1.326909262,2.244538031,-0.43022599799999994,-0.525913307,-0.9244497759999999,-0.38361987299999994,0.193181496,-0.510328529,-3.27520133,-0.278912919,-1454.6996704852208 -3256,3256,E195M,-0.122862521,0.234879272,0.10065385199999999,0.065335057,-0.8699149409999999,0.851551072,-0.0018728929999999998,-0.243852149,-0.21601186100000003,0.425081511,0.044677033,0.08346532,0.11784238300000001,0.27284667,-0.14217655699999998,-0.33188044,-1.407949441,0.30139603800000003,1.3903839919999998,-5.696366808,-4.944514702,-6.064701576,-5.212213196,-5.734535759,-6.525868805,-6.293609577000001,-4.234397667,-1465.5479574133642 -3257,3257,E195L,-0.084067545,-0.397965874,-0.37679637899999996,-0.6219119470000001,-1.055149919,0.42846297299999997,-0.012882215,-0.155252875,-0.122192925,-0.407427401,-0.388504347,-0.368832351,-0.384760406,-0.664397593,-0.5794263000000001,-0.972503826,-1.1377960120000001,3.140778147,2.793087363,-5.059773688,-4.6001270519999995,-5.802308189,-4.407946723999999,-5.207191765,-5.281294708,-5.996078766,-3.737203751,-1464.803456935566 -3258,3258,E195N,-0.049127584,-0.080440976,-0.036024399,-0.009626675999999999,-0.07625021900000001,0.14506358800000002,0.023339082999999997,-0.121594251,-0.025565012999999998,-0.132597518,-0.028284434,-0.069868788,-0.00218001,-0.036508714,0.017255363,-0.132597518,-0.019902918999999998,1.414912983,2.238588498,-0.466420021,0.247405975,-0.677656853,-0.045178062000000005,-0.662883064,-1.193788101,-2.518482239,-0.7203244000000001,-1457.3128281403333 -3259,3259,E195Q,-0.020379293,-0.03850404,0.01013564,0.023373832999999997,-0.013494444,0.039016452,-0.014336218000000001,-0.026422367000000002,0.035690356,-0.0008872210000000001,-0.076120859,0.034367086,-0.014095806,0.047237772000000004,-0.0004901069999999999,0.025265497999999997,-0.052254385,1.092391433,2.6684853040000003,-1.6071118999999998,-1.449537735,-2.124439713,-1.088717819,-1.423387398,-1.949476837,-3.428548039,-1.171889624,-1461.3708425438963 -3260,3260,E195P,-0.010213574,-7.47e-05,-0.007815853000000001,0.028697208999999998,0.007968436,0.004762216,0.011292844,-0.031719991,-0.003145787,0.010232372,-0.010381813,0.031815609,-0.047447315,0.077719195,-0.020324777,0.026309081,-0.010372209,0.881261428,2.670307651,-1.462621983,-0.8465150220000001,-1.7283849409999998,-0.136476791,-2.1934505840000003,-2.408282578,-3.41096827,-2.089886501,-1451.939408914186 -3261,3261,E195S,0.00928002,0.041292016,0.033530855,0.073607039,0.001405108,0.060100043,0.036323552,-0.017763512,-0.012122454,0.032519831,0.050064199999999996,0.035598137,0.031463572,0.09260433,0.054609748,0.01659494,-0.013784724,1.217359958,2.837393005,-0.872362848,-0.42575180100000004,-1.37399144,-0.072151794,-1.317022667,-1.172896538,-2.809707,-1.070286251,-1456.7622860111296 -3262,3262,E195R,-0.035118854,0.028829632,0.00760883,0.021661381,0.002125497,0.177633583,0.003986085,-0.074223792,-0.09213701199999999,0.007145797,0.050513467,0.002305508,0.012912152,0.026446781000000003,0.01687598,-0.015383633,0.019634626000000002,1.19055673,2.5545812619999997,-2.288504901,-1.929339661,-3.166964478,-1.44704171,-2.73958165,-2.159597008,-4.088444817,-0.800399063,-1451.5753642129712 -3263,3263,E195T,0.008816169,0.070888909,0.048822095,0.046090901,0.004035174,0.056182639000000006,0.019194368,-0.00156203,-0.042245905,0.060747032,0.081030785,0.041795337,0.055848852000000004,0.027492378999999997,0.064689422,-0.024227642999999997,0.03229799,1.307373761,2.601030351,-0.977319864,-0.492728531,-1.288054619,0.101665535,-1.96776075,-1.239720955,-3.838517192,-0.997731875,-1460.5455851275474 -3264,3264,E195W,-0.009267971,-0.159449441,-0.09586918900000001,-0.13672318,-0.974195725,0.727539807,0.009353437,-0.027889378,-0.341020079,-0.059865080999999994,-0.259033801,-0.062662716,-0.129075661,-0.279046712,0.005600351999999999,-0.5291609979999999,-1.4192304519999999,2.193523213,2.351403295,-6.890139909,-5.913692284,-7.944561118999999,-5.8597783429999994,-7.047232384,-7.685435417000001,-7.652963445,-5.72972932,-1468.117078979034 -3265,3265,E195V,-0.09285711699999999,0.011106946999999999,-0.090780039,-0.06345782,-0.7748448640000001,0.7419667259999999,-0.045999110999999995,-0.139715122,-0.44155445600000004,0.012402382,0.009811511,-0.137158339,-0.044401737999999996,-0.17431136100000003,0.047395720999999995,-0.531930154,-1.017759574,1.7600916309999999,2.003292338,-4.859701041,-4.101743065,-4.991648743,-4.234585013999999,-5.169783875,-5.800744507,-5.8264113889999996,-3.7176565160000004,-1464.3060004380532 -3266,3266,E195Y,-0.250920199,0.07093089999999999,-0.213553298,0.043641234,-0.562971902,0.779078983,-0.191604818,-0.310235579,-0.39078507799999995,0.18317296800000002,-0.041311167999999995,-0.092625939,-0.334480656,0.16975326699999999,-0.08247080000000001,-0.268394182,-0.8575496220000001,0.742020426,1.579156875,-5.477763542000001,-4.477521446,-6.185024925,-4.5500226139999995,-5.8455446470000005,-6.330704078999999,-6.759550107999999,-4.655115836,-1467.9269713675603 -3267,3267,L196A,0.013511546999999999,-0.023375649,-0.023564118,-0.013781833,-0.014103408000000001,0.008321783000000001,-0.013955126000000002,0.040978218999999996,,-0.027801499,-0.018949799,-0.028771326,-0.01835691,-0.015342286,-0.012221379,-0.016018021,-0.012188794,1.275895449,2.556860795,-0.091525543,0.003977318,-1.1778379140000002,2.06191774,-0.9442897109999999,-0.401395149,-1.537310894,0.41470202700000003,-1466.254980402533 -3268,3268,L196C,0.069760885,0.008363096,0.021806966,0.050380667999999997,0.029851428,0.022712748999999997,0.07034801,0.069173759,,0.061388317000000005,-0.044662125,0.04156188,0.002052051,0.025706085,0.07505525099999999,0.049022749000000004,0.010680106000000002,1.189518643,2.987475843,-4.862336287,-3.7546576160000003,-4.947948006,-4.66144416,-5.966102768,-4.981528885,-4.864213715,-2.920735483,-1460.0948501322418 -3269,3269,L196E,-0.007915552,-0.041762433,-0.023924637000000002,-0.02754187,-0.008205434000000001,0.012594306000000001,-0.028201504,0.0123704,,-0.032565289,-0.050959576,-0.009950605,-0.037898667999999996,-0.067553008,0.012469268,-0.010071478,-0.00633939,1.224566242,2.396587879,-4.901392635,-3.602012383,-5.153275642,-4.0033951189999994,-4.94045092,-6.807829109,-3.555781645,-3.193917153,-1452.8344734585844 -3270,3270,L196D,-0.0045067679999999995,0.01938639,-0.020576894,-0.013560445,-0.00834174,0.02113384,-0.035816384,0.026802847999999997,,0.052817105999999996,-0.014044326999999999,0.024710377999999998,-0.065864165,0.025149336,-0.052270225,0.015939211000000002,-0.03262269,1.186092017,2.550758115,-6.091553067,-4.49899131,-6.4946291810000005,-4.752113411,-6.0149539260000005,-8.697077507000001,-4.69568866,-3.872769361,-1453.1801545429043 -3271,3271,L196G,0.034063842000000004,0.0052497509999999995,0.022944604,0.009171503000000001,-0.005089222,0.043119985,0.033669005,0.034458678,,-0.005992725,0.016492226000000002,0.023149122999999997,0.022740085,-0.012856845,0.03119985,-0.03617423,0.025995787000000003,1.254713108,2.470105786,-2.851172108,-1.688632736,-4.065036774,-1.0254158709999999,-3.378366348,-4.098408813,-2.367303133,-1.622627917,-1460.7919354699552 -3272,3272,L196F,0.07343807599999999,0.014319513,0.015627428999999998,0.034377646,0.026951397000000002,-0.02047721,0.06183005,0.085046102,,0.012486605,0.016152421,0.02442783,0.006827028000000001,0.007126232,0.06162906,-0.014750518999999998,0.068653313,1.334604692,2.6858635730000002,-4.103047223,-4.338410919,-3.5418743360000002,-3.519350853,-4.678425461000001,-4.437174545,-3.499190281,-1.847053595,-1455.7916178745218 -3273,3273,L196I,0.044951287,0.012109375,0.033721096,0.005935301,-0.000868318,0.012479671999999999,0.009325323,0.080577251,,0.016218656,0.008000093,0.048177492,0.019264700000000003,0.002327349,0.009543253,-0.025111414,0.023374779,1.087457987,2.349038116,0.785169978,1.174452606,0.170403625,1.4748841480000001,1.11228228,-0.006172768,-0.7299555320000001,-0.782241086,-1462.7381685036235 -3274,3274,L196H,0.05525830599999999,0.040055925,0.035533666,0.019795313999999998,0.032170135,0.002347854,0.042577023,0.067939588,,0.040594371000000004,0.039517477999999995,0.021187393,0.049879939000000005,0.023581425,0.016009203,-0.005186299,0.069526568,1.285115094,2.716921905,-4.1237758730000005,-2.682754578,-4.4222952189999996,-3.744860168,-4.635109596,-5.133859802,-3.49085863,-3.435329776,-1454.752829323057 -3275,3275,L196K,-0.020741213,0.007963435,-0.030197788,-0.019914961000000002,-0.023462475,0.064083112,-0.025243419,-0.016239006,,0.057766752000000005,-0.041839883,-0.020833268000000002,-0.039562307000000005,-0.0052617869999999995,-0.034568135,0.045726058,-0.092651007,1.218124703,2.7516917419999998,-4.212983546,-2.72179039,-4.460869209,-3.268997505,-3.91226857,-6.700992058,-3.5914703739999996,-3.1618279489999996,-1455.4816039660946 -3276,3276,L196M,-0.034296794,-0.01369696,-0.023029123999999998,0.016470899,-0.005650776999999999,0.000164887,-0.028155211,-0.040438376,,0.006586835,-0.033980754,-0.002522618,-0.043535629000000006,0.047986497,-0.015044700000000001,0.008631686999999999,-0.019933241,1.183163949,2.647552304,-2.204690822,-2.405503021,-1.89712075,-2.145755501,-1.284422409,-3.290652428,-3.6239282960000003,-2.7749630080000003,-1462.3066235338338 -3277,3277,L196N,0.055590453,0.010300303,0.018395599999999998,0.008056246,-0.017572607,-0.034108976,0.024540162999999997,0.086640743,,-0.010163970999999999,0.030764576000000002,0.016378333999999998,0.020412866,-0.010913511,0.027026002,-0.061884539,0.026739326,1.3540001240000001,2.4117253119999997,-4.630576305,-3.57007901,-5.114263214,-3.813794304,-5.078875877,-5.575869118,-3.650693733,-3.081068441,-1456.4226775732823 -3278,3278,L196Q,0.039906886,0.011349413999999999,-0.012393072,-0.001108468,0.020486085,0.020256301,0.035623537000000004,0.044190235,,0.023234875,-0.000536047,-0.029850959,0.005064815,-0.043622296,0.041405361,-0.010698082,0.051670252,1.335417477,2.512888706,-4.582441042,-3.5800466839999996,-5.079060745,-3.7719860310000004,-4.018432205,-6.462679542999999,-4.164736193,-3.7118973310000003,-1454.7796219107695 -3279,3279,L196P,0.025067476,0.022386771,0.00192985,0.005183206,-0.019686099999999998,0.02006191,-0.005732874000000001,0.055867825999999995,,0.023619277,0.021154264,-0.001332088,0.005191787,-0.006173528,0.01653994,-0.032193973,-0.007178225999999999,1.225906852,2.40118045,-4.840714388,-3.5139797130000003,-4.653661491,-3.890343033,-5.378092422000001,-6.767495277,-3.843820837,-3.551915553,-1451.379446345847 -3280,3280,L196S,0.046805005,0.014536051999999999,0.015749972,0.001994899,-0.009026136,-0.013431392,0.033379226,0.060230782999999996,,0.025336095,0.003736008,0.003606878,0.027893065,-0.018199872,0.02218967,-0.025258619,0.007206346999999999,1.20193819,2.4345805119999997,-2.462293846,-1.6819702909999998,-3.112411125,-1.0513495940000002,-3.1251881710000005,-3.340550049,-2.58349418,-2.8359459719999998,-1460.3403021832928 -3281,3281,L196R,0.054531513,0.048388695,0.026178996,0.022509319,0.027352755,-0.010856282,0.045535785999999995,0.063527239,,0.061714822999999995,0.035062567,0.034104712999999995,0.018253278,0.012762261,0.032256376,0.011214247,0.043491262,1.153649773,2.7310517560000003,-2.527773511,-1.51847168,-2.493927834,-2.676964989,-2.358871117,-3.590631935,-2.3050055019999998,-2.2766911569999997,-1455.3635579794645 -3282,3282,L196T,0.017822284,0.008293742,-0.010173642,-0.011032688,0.005459075,0.02100357,-0.000368212,0.03601278,,0.029090212,-0.012502728000000001,0.007074099,-0.027421382,0.004799983,-0.026865358,-0.000503486,0.011421636,1.1471525470000001,2.739505421,-0.057463766,0.303298035,-0.6715425190000001,1.16073378,-0.528620354,-0.551187775,-0.7601076440000001,-1.7098582219999998,-1464.0724093373865 -3283,3283,L196W,-0.0015222529999999999,-0.012566266999999999,0.008912145,-0.012437375,-0.004021524,0.024990033,-0.005712509,0.002668003,,-0.016251841,-0.008880691999999999,0.034916159,-0.01709187,0.000545886,-0.025420636,0.014174508999999998,-0.022217557000000002,1.200270332,2.547443944,-4.867541237,-4.3144935460000005,-5.185991585,-3.990898521,-5.601040871,-5.245281662,-4.158895575,-2.726224217,-1455.431881448254 -3284,3284,L196V,0.010276203000000001,-0.005372231999999999,-0.023952922999999997,-0.01545311,0.02295313,0.032045673,0.005247354,0.015305051,,0.007642746,-0.01838721,-0.002391491,-0.045514355,0.00025563,-0.031161849,0.034748499,0.011157761,1.075444182,2.612986375,1.7183941930000002,1.8289771119999998,0.977991356,2.75218502,1.796577965,1.23623951,-0.997966224,-0.190258578,-1469.187919199001 -3285,3285,L196Y,-0.006163126999999999,0.02663334,-0.00985417,-0.002390429,-0.01937016,0.007733659,-0.026577181000000002,0.014250928000000001,,0.035320516,0.017946164,0.0059129,-0.025621239,-0.01010017,0.005319313000000001,-0.047369987,0.008629668,1.239348798,2.5122110980000003,-5.019418513,-3.660534775,-4.97061454,-4.118027916,-5.722555756,-6.6253595810000006,-4.606030167,-2.7733727669999997,-1453.8841306138784 -3286,3286,L197A,-0.02373761,0.030910595,0.00679504,-0.653330671,-1.6978221230000001,0.047662292,0.025849719,-0.07332493799999999,-0.052145342000000004,0.042514002,0.019307188,-0.00999663,0.023586708999999997,-0.534969087,-0.771692255,-1.627592947,-1.768051298,1.91282619,1.569657129,-14.33855925,-14.68527869,-14.3262761,-14.03139686,-14.71773802,-13.93210659,-7.4147697379999995,-2.455389584,-1456.3826318401843 -3287,3287,L197C,-0.08468815199999999,-0.0011807089999999998,-0.034669583,-0.931600656,-2.045410784,0.069618496,-0.071780545,-0.097595758,-0.049442393,-0.018621465,0.016260047,-0.031428102,-0.037911064,-0.697853852,-1.16534746,-1.94427319,-2.1465483780000003,1.900936641,1.4501418869999998,-15.19058721,-14.54637556,-15.68886865,-16.55536907,-14.27505969,-14.88726307,-8.437451121,-4.702317055,-1458.9903112230822 -3288,3288,L197E,-0.059060912,0.02084969,0.037753186,-1.282698409,-2.296573983,-0.023808541000000003,0.000554904,-0.11867672800000001,0.05573352,-0.013732545,0.055431925,0.062615367,0.012891005,-0.9348734759999999,-1.630523341,-2.3195955109999997,-2.273552455,1.6730541630000002,1.14794094,-16.77133755,-16.53854823,-17.92340133,-17.64644926,-16.39650708,-15.35178188,-8.391789159,-5.435059967999999,-1465.1058783018962 -3289,3289,L197D,-0.080197538,0.048740720999999994,-0.032296513,-2.055621736,-2.265152026,-0.049183194000000006,-0.029963811,-0.130431264,-0.012699574,0.082961884,0.014519558,-0.016987437,-0.047605588,-2.44511489,-1.666128581,-2.01029299,-2.520011061,0.332960202,0.431602035,-18.96284668,-18.90223913,-21.19070544,-19.86143558,-17.28258393,-17.57726931,-10.1188955,-7.750218857,-1467.3364846892655 -3290,3290,L197G,-0.024151718,-0.010227798,-0.016402429,-0.896759172,-2.0468747119999997,-0.023708635,0.00607678,-0.054380215999999995,-0.008365334,0.004578706,-0.025034301000000002,-0.026898363999999998,-0.0059064930000000005,-0.654828895,-1.138689448,-1.865191655,-2.228557768,1.950233434,1.501140493,-16.33516712,-15.96907021,-17.40682607,-17.04076817,-16.12968028,-15.12949089,-7.135209439,-3.209124218,-1459.3904519458301 -3291,3291,L197F,-0.010194751,0.105238352,0.03118113,0.024397783,-1.641900013,0.09514278300000001,0.012685096000000002,-0.033074598,-0.025305865,0.15409637199999998,0.056380331,0.047052595,0.015309665,0.051272585999999995,-0.00247702,-1.303337775,-1.9804622509999998,0.690390095,1.33141229,-10.22195601,-10.28533062,-11.30362936,-10.66267838,-7.877249527000001,-10.98089219,-6.683239695,-3.349526525,-1453.4544515907764 -3292,3292,L197I,-0.08438760099999999,-0.032492639,-0.082799487,-0.040662013,-0.537680195,0.001915045,-0.05453011,-0.11424509199999999,0.002426232,-0.030141542,-0.034843735,-0.070846197,-0.094752776,-0.046935335999999994,-0.034388689,-0.38871085899999996,-0.6866495309999999,1.5859541659999998,2.0045595130000002,-9.811884001000001,-9.677166199,-12.29070658,-10.048380400000001,-9.908395042,-7.1347717820000005,-6.180701676,-2.217429491,-1442.6703066988848 -3293,3293,L197H,-0.081098016,0.007884811,-0.003634123,-0.09389539599999999,-1.6608918519999998,0.067213149,-0.016498376000000002,-0.145697656,-0.08784299300000001,-0.00459304,0.020362662,-0.021475574,0.014207329,-0.13997286,-0.047817930999999994,-1.487030083,-1.834753621,1.146197058,1.369251595,-16.6228701,-15.504476,-18.08422813,-18.50733913,-14.39391035,-16.6243969,-9.102078377,-6.37422245,-1468.6197082847357 -3294,3294,L197K,-0.13044991,0.070248184,0.022180473,0.034133069,-1.7100462269999999,0.121101452,0.035201587,-0.296101407,-0.114400745,0.057813629000000005,0.08268273799999999,0.01156402,0.032796925,-0.051630458,0.119896596,-1.455657648,-1.964434805,0.733091222,1.324843576,-16.58521245,-16.64350282,-19.176035199999998,-16.87603623,-14.61302065,-15.61746734,-9.1729386,-6.753484387,-1466.2232177262194 -3295,3295,L197M,-0.197201075,0.069362302,-0.050992398,-0.031921177,-0.51859851,0.065988873,-0.131097712,-0.263304437,0.041392685,0.20309481100000001,-0.064370207,0.118476864,-0.22046166,0.056865042000000005,-0.120707396,-0.282603888,-0.7545931309999999,0.575632978,1.496304006,-8.332552968,-9.189344131,-9.990128197,-8.061936134,-6.4834755170000005,-7.937880859,-6.7787166,-4.407740592,-1450.0857627065852 -3296,3296,L197N,-0.079909305,-0.008459412,-0.093345703,-0.40581473700000004,-2.089523293,-0.024413894,0.044211771,-0.20403038,0.018275957,-0.054410117,0.037491294,-0.146672608,-0.040018798,-0.386474346,-0.425155128,-1.7809562190000001,-2.398090366,1.634735838,1.4239285869999998,-15.86103478,-16.54899535,-15.53772618,-17.70119572,-14.47622852,-15.04102815,-8.188958884,-5.500778401,-1463.8985590119846 -3297,3297,L197Q,-0.12907553300000002,-0.077810518,-0.065311732,-0.301647647,-1.88757772,-0.010478115999999999,-0.060071821,-0.198079244,-0.0068259869999999995,-0.11033690300000001,-0.045284133,-0.11328962,-0.017333843,-0.287902847,-0.315392446,-1.850592147,-1.924563293,1.5633530709999999,1.3984765909999999,-14.63586214,-15.28351138,-15.77565985,-15.11880817,-12.71246116,-14.28887012,-8.924597773,-6.145635274,-1467.08293243777 -3298,3298,L197P,0.016845873,-0.016613922,-0.00724059,-1.3535414890000002,-1.975856504,-0.038515171,0.011606027,0.022085719,-0.005427859,-0.027375642000000002,-0.005852202,-0.054556364,0.040075184,-1.310168591,-1.396914386,-1.9874301069999998,-1.964282901,2.7725594819999997,1.890368415,-15.2799201,-15.42495692,-16.68807301,-14.87172769,-15.03188857,-14.38295432,-8.175279796,-6.012896349,-1462.6521935253404 -3299,3299,L197S,-0.022285811000000003,-0.001438346,-0.02522251,-0.367586211,-1.7293676269999998,-0.008146814,-0.015491121000000002,-0.029080500000000002,-0.00822033,0.004619092,-0.007495784,-0.020380217,-0.030064802999999998,-0.316054499,-0.41911792299999995,-1.6588406409999998,-1.799894612,1.511261138,1.416924946,-14.59886027,-15.02694459,-14.034661900000001,-15.72784817,-14.12911869,-14.075728,-7.540516267999999,-4.673359822,-1456.2495416002348 -3300,3300,L197R,-0.055881973,0.076828662,0.064752299,-0.054788797,-1.8241070480000001,0.39500082299999995,-0.0025380629999999997,-0.10922588300000001,-0.19920822800000001,0.080783347,0.072873976,0.023049747000000002,0.10645485,-0.11480116900000001,0.005223576,-1.60147995,-2.046734146,0.969068422,1.334456217,-14.69292516,-14.86406073,-15.91568047,-15.4926286,-13.37062941,-13.82162656,-7.999536632000001,-5.541707484,-1467.6746476474218 -3301,3301,L197T,-0.017429553,-0.005187169,-0.0028337279999999998,-0.48151009999999994,-1.970737178,0.006274136,0.007599422,-0.042458527,-0.020083583999999998,0.01336471,-0.023739048,-0.035374941,0.029707486,-0.322073525,-0.6409466739999999,-1.828194795,-2.113279561,1.438013215,1.371344602,-14.57646696,-14.5348147,-16.65854028,-13.73897684,-14.65837626,-13.29162673,-8.118491673,-4.387373447,-1455.0720635829493 -3302,3302,L197W,0.028174208,-0.018779027,0.033650542,-1.734340475,-2.2530959680000002,0.102615383,0.057163930999999994,-0.000815515,-0.0020152910000000002,-0.044493448,0.006935395,-0.0025817179999999998,0.06988280200000001,-1.8214942490000001,-1.6471866999999998,-2.5170061169999998,-1.989185819,0.637419759,0.67546385,-14.60413,-14.72904951,-15.83919521,-15.53082522,-12.56078399,-14.360796100000002,-8.715948681,-5.836764771,-1462.5693140546791 -3303,3303,L197V,-0.04725801,-0.058101129,-0.084076317,-0.11158465,-1.583193307,0.054976992999999995,-0.008788948000000001,-0.08572707199999999,-0.010002618000000001,-0.09692955,-0.019272707,-0.143236,-0.024916634,-0.179781813,-0.043387485999999996,-1.4939855380000002,-1.672401075,1.3863721830000002,1.4199477040000001,-10.72377329,-9.668044037,-13.312131099999998,-10.38218953,-11.49853909,-8.757962692000001,-6.562908557999999,-1.8593383999999997,-1453.6346020591445 -3304,3304,L197Y,-0.050337507000000004,0.023080418,-0.030729267999999997,-0.24669205,-1.8213058880000002,0.011798278999999998,0.006615313,-0.10729032699999999,-0.026597767999999997,0.023739937000000003,0.022420898999999998,-0.111166809,0.049708273,-0.26616433,-0.227219769,-1.553564894,-2.089046882,1.41708667,1.4100202590000002,-15.81449498,-15.11707778,-18.65466459,-16.45438425,-12.41579762,-16.43055068,-8.736434597,-6.108585188999999,-1457.7085622451268 -3305,3305,T198A,-0.02430502,0.009397561,0.01368525,-0.012103678,-0.05716975,0.103005075,0.009123947,-0.057733987,0.051051028,-0.04758078599999999,0.066375908,0.034468539,-0.007098039,-0.019009263999999998,-0.0051980920000000005,-0.057902269000000006,-0.05643723,1.234517724,2.364232475,-2.518744803,-2.4828212130000002,-2.49092778,-2.9352905810000003,-1.860446693,-2.8242377469999997,-4.003327582,-0.12342196400000001,-1466.843426903244 -3306,3306,T198C,0.009769318,0.068221059,0.006597798,-0.008918587,-0.095859568,0.024798522000000003,0.015738787,0.003799849,0.029790063,0.06365219,0.072789927,0.021671665,-0.008476069000000001,0.018530546999999998,-0.03636772,-0.084723769,-0.106995366,1.291317871,2.309880284,-6.8222442029999995,-6.24074086,-6.0740379639999995,-7.7371591870000005,-6.574850327,-7.484432677999999,-7.405995827000001,-4.21485153,-1465.4211008637212 -3307,3307,T198E,0.009339796,0.007257771,0.015293863000000001,-0.004027421,-0.0266382,-0.013795318999999999,-0.011827491,0.030507082,0.06557773900000001,0.00623732,0.008278221,0.01039142,0.020196306,-0.01322481,0.005169968,0.023226232000000003,-0.076502632,1.0636548909999999,2.643429168,-4.195633488,-3.606579422,-4.210905853,-5.269645081,-3.1255945130000002,-4.765442574,-4.685455694,-1.4725140980000002,-1454.7485281154513 -3308,3308,T198D,-0.062204837,-0.034206545,-0.036889812,-0.04560963,-0.222104265,0.050914265,-0.040350261,-0.08405941300000001,-0.037051487,-0.06417205299999999,-0.0042410370000000005,-0.010442395,-0.06333722900000001,-0.037730207,-0.053489052999999995,-0.142463694,-0.301744835,1.56681266,2.358869154,-5.909622392,-3.3802083210000005,-7.113690628,-8.27382679,-4.487704788,-6.292681435,-6.102059639,0.051128202000000005,-1448.9870649329387 -3309,3309,T198G,-0.012654676,-0.016008398,-0.02678368,-0.036064507,-0.07310684099999999,0.019895788,0.004219222,-0.029528573,0.040418094,-0.028591704,-0.0034250920000000002,-0.017403992,-0.036163368,-0.046874562,-0.025254452,-0.053916619000000006,-0.09229706300000001,1.4106899,2.57426162,-5.18503795,-4.493016418,-4.682470024,-6.675770844,-5.132036972,-4.9418954930000005,-5.559376275,-0.22678826300000002,-1464.5342949293554 -3310,3310,T198F,-0.004546573,-0.005452129,0.0037566509999999997,-0.017958787,-1.5654307619999999,0.000105479,0.035116276,-0.044209421,0.091106044,-0.042845007000000004,0.03194075,-0.017951997,0.025465297999999997,-0.061819418,0.025901844,-1.315426468,-1.815435055,0.852603014,1.345923356,-8.527825567999999,-8.332944695,-8.113537155,-8.88006041,-7.659754257,-9.652831322,-9.154796617999999,-6.728775792,-1468.007998922374 -3311,3311,T198I,-0.063273551,-0.009961161,-0.012107406999999999,-0.085033599,-1.705973767,-0.01314193,-0.067487959,-0.059059143,0.065676026,-0.010512479,-0.009409843000000001,0.005400666,-0.029615479,-0.084806445,-0.085260752,-1.4893543630000001,-1.922593171,0.836590065,1.331621733,-6.336802771,-6.905911307999999,-5.945918967999999,-6.747490044,-5.190016708,-6.894676826,-7.270542271,-3.9568317339999997,-1466.2894496275112 -3312,3312,T198H,-0.024420169,-0.020859985,-0.017254343000000002,-0.011948385,-0.10664656,0.033301512000000005,-0.033646042,-0.015194296000000001,-0.004144022,-0.042091979,0.00037201,-0.020350095,-0.014158591000000002,-0.028398549,0.004501779,-0.085115118,-0.12817800099999999,1.345602054,2.2951076969999997,-5.633867694,-6.016578902999999,-4.906433502,-6.670037262,-4.857148438,-5.719140366,-5.7743796629999995,-1.7672841369999999,-1467.7398633016273 -3313,3313,T198K,-0.010990669,-0.028021214,-0.014451903,-0.049482217,-0.066967809,0.037599825,0.014886719,-0.036868056,-0.031905243,-0.026245745,-0.029796682,0.0010158419999999999,-0.029919647,-0.022781055,-0.076183378,-0.041048667000000004,-0.092886951,1.4113049519999998,2.545440026,-1.857744144,-1.7265197140000001,-1.70435305,-2.052472115,-1.2564380720000001,-2.548937767,-3.931617575,-0.774115152,-1469.755223752465 -3314,3314,T198M,-0.048000773,-0.009600803,-0.024409602000000002,-0.026338835,-0.368987389,0.040685648,-0.053749923,-0.042251622,0.060363380999999994,-0.038612326,0.01941072,0.001029955,-0.049849159000000004,-0.013053687,-0.039623982,-0.28983566899999996,-0.448139109,1.190991382,1.805726867,-5.748700327000001,-6.059445801,-5.557713347999999,-5.866371254,-4.575555023,-6.684416206,-7.447848932,-4.662686543,-1465.971558982972 -3315,3315,T198L,-0.008753832,0.032829695,-0.0024923429999999997,-0.004815249000000001,-0.607306196,0.04793406099999999,0.0020407,-0.019548364,0.029809652000000002,0.033629404,0.032029985,-0.005387744,0.000403059,-0.006306142,-0.0033243559999999997,-0.39199555799999997,-0.8226168340000001,0.951109855,1.582936389,-3.82050249,-4.089446068,-3.650866974,-4.1759890980000005,-3.045033974,-4.141176338,-5.647929781,-2.699047205,-1460.8635498625226 -3316,3316,T198N,-0.023748906,0.019390051000000002,-0.036500896,-0.040954832999999996,-0.088840844,0.054281907000000004,0.005911475,-0.053409287,0.068625935,0.033721728,0.005058374,-0.057460539000000005,-0.015541253,-0.009027636,-0.072882029,-0.067981655,-0.109700033,1.138919645,2.312666501,-3.680244722,-2.387767265,-3.6271511760000004,-5.68516526,-2.902251938,-3.79888797,-5.754093885,-0.11420695900000001,-1465.239730139263 -3317,3317,T198Q,-0.046244981,-0.033257141000000004,-0.0795992,-0.03555395,-0.08707831199999999,0.04037621,-0.049239675,-0.043250287000000005,-0.005271306,-0.029133691,-0.03738059,-0.130922875,-0.028275524,-0.023257751,-0.047850149,-0.090148542,-0.084008082,1.3930351159999999,2.354162419,-2.7895670089999998,-3.296104805,-2.590100754,-3.18728289,-1.909681839,-2.964664757,-4.254681307,-1.499978185,-1465.4319875366054 -3318,3318,T198P,-0.047288657000000005,0.000771711,-0.015981098,-0.021019636,-1.642965451,0.073107128,-0.01773734,-0.076839974,0.040775412000000004,-0.024788157,0.026331579,-0.003420505,-0.028541691,-0.035166422999999995,-0.006872849,-1.509094126,-1.776836775,0.71936057,1.324869684,-5.423520448,-3.876521866,-5.228850967,-5.553514915,-4.894772018,-7.563942474,-4.174025278999999,0.377110995,-1456.3582892147824 -3319,3319,T198S,0.03354011,0.01913275,0.004015326,-0.009908356,0.034374676,0.030568501,0.042863787,0.024216433,0.027171957000000004,-0.011798397,0.050063897,-0.026843441000000003,0.034874092,-0.03401127,0.014194558000000001,0.013083553000000001,0.055665799,1.329394115,2.732324823,1.264865793,1.147486298,1.638088768,1.224643387,1.282012894,1.0320976179999999,-1.205200402,1.6751538000000001,-1467.0375732732937 -3320,3320,T198R,-0.031109734,0.008442273,0.010616511,-0.014291511000000002,-0.130710025,0.121282454,-0.00567576,-0.056543708,-0.004114056,-0.012427156000000002,0.029311702000000002,0.01342378,0.007809241999999999,-0.010707176,-0.017875846,-0.09393392,-0.167486129,1.312071236,2.2730988080000003,-3.601698499,-4.096873184,-2.818957237,-4.457721588,-3.196193146,-3.4387473369999997,-5.277946362,-1.1883912079999999,-1471.630821055267 -3321,3321,T198W,-0.043606541,-0.002922031,-0.012878631000000001,-1.3037206140000002,-1.9821144419999999,0.101650931,-0.015805788,-0.071407293,-0.009609625,-0.041578718,0.035734657,-0.043405132,0.01764787,-1.243658798,-1.36378243,-1.927556396,-2.0366724880000002,2.8462297430000003,2.000198331,-9.119641844,-8.919905792,-8.540743767,-10.10304659,-8.104820213,-9.929692863,-9.551342146,-7.836974435,-1471.9937904868275 -3322,3322,T198V,-0.039122313,-0.028211985,-0.023886819,-0.034497706,-1.215136884,0.068242245,-0.0037568479999999997,-0.074487777,0.04346811,-0.067264877,0.010840908,-0.042636762,-0.005136875999999999,-0.062503481,-0.00649193,-0.863313958,-1.56695981,1.0773720690000002,1.461354052,-5.806068761000001,-5.585182372999999,-5.511414352,-6.19105201,-5.042835426,-6.699859642000001,-6.523033713999999,-2.797522935,-1466.34414695343 -3323,3323,T198Y,-0.021000305,0.014599615,0.004004614,-0.020075151,-1.5363400930000002,0.059665484000000005,-0.017884,-0.02411661,0.047285371,0.026498367999999998,0.0027008609999999997,-0.002039731,0.010048959,-0.042027895999999995,0.001877595,-1.290292175,-1.78238801,0.759389395,1.3361049170000001,-8.684597238,-9.470485275,-8.217684799,-9.017091934,-7.23429744,-9.483426742999999,-8.227637148,-4.653092039,-1472.2697710017674 -3324,3324,L199A,-0.027031687999999998,-0.017196592,-0.028033655,-0.014487156999999999,0.015100529,8.87e-05,-0.027035427,-0.027027949,0.04625177900000001,0.0041767440000000005,-0.038569927999999996,-0.020353345,-0.035713965,0.012653535,-0.041627849,0.015309503,0.014891555,1.200850847,2.7073447880000003,1.95162793,1.194707817,1.4852526780000002,2.490416359,1.909647011,2.678115784,-0.687031912,1.97142271,-1463.3700387668796 -3325,3325,L199C,-0.078652536,-0.010805173999999999,0.00030676900000000003,-0.030406042,0.012399982,0.048468403,-0.06959473,-0.087710341,0.044969564000000004,0.030666324,-0.052276672,0.027562775,-0.026949237,0.039484789,-0.10029687300000001,0.026342132,-0.0015421679999999998,1.251126816,2.7770330810000003,-3.4166620030000003,-3.433863495,-3.438786865,-3.3388414539999998,-3.536896133,-3.3349220660000003,-6.324529532000001,-3.700717006,-1463.8765722927637 -3326,3326,L199E,0.02022208,-0.037953197,-0.032597793,-0.021098059,-0.004804214,0.001247656,-0.004034397,0.044478555999999995,0.007996771,-0.039667552,-0.036238841,-0.04377618,-0.021419405,0.002678643,-0.04487476,0.015414076,-0.025022503999999997,1.3446759,2.8066103439999996,1.5901170409999998,1.302687744,1.299540833,1.5590134430000002,1.318516762,2.470826424,-2.0370369409999998,1.599302077,-1465.014835246373 -3327,3327,L199D,-0.040595208,-0.039818674,-0.054353713,-0.040196833,-0.058771055,-0.064835412,-0.062775807,-0.018414609,0.058867015,-0.016726928999999998,-0.062910418,-0.090383995,-0.018323431,-0.021542146,-0.058851519000000005,-0.053720238,-0.063821871,1.435469301,2.507989315,1.057590759,0.6758912659999999,0.571486458,1.325356667,1.12924086,1.585978546,-2.6007879590000003,0.8289577440000001,-1461.5360517161898 -3328,3328,L199G,-0.033864266000000004,-0.008566498,-0.0407965,-0.022544106,-0.004201456,-0.005685898000000001,-0.046428622999999995,-0.021299908,0.019575926,0.00593859,-0.023071586,-0.032608424,-0.048984575,-0.016100922,-0.02898729,-0.011903493000000001,0.0035005809999999996,1.322113845,2.63932888,-0.08958003699999999,-0.36398304,-0.060746178,0.589893684,-0.356437454,-0.256627197,-4.250416125,0.270899409,-1460.265413703397 -3329,3329,L199F,-0.017045945,0.011424523,0.01892704,0.003213487,0.063373193,-0.101687211,-0.07115254,0.03706065,0.06704360599999999,0.05269354,-0.029844495,0.075124161,-0.037270082,0.054314108,-0.047887135,0.121761435,0.004984951,1.036155153,2.988611183,-3.257868896,-3.353865646,-3.214160736,-3.6948995439999996,-2.9868716280000003,-3.039546928,-6.037922517999999,-3.552481743,-1468.3466686489992 -3330,3330,L199I,0.006648490999999999,0.062682639,0.00522337,-0.007024595,0.06277263400000001,-0.03384584,-0.011678718999999999,0.0249757,-0.000792968,0.11674356699999999,0.00862171,0.014560597,-0.004113858,0.012466992,-0.026516181,0.091146146,0.034399122000000004,1.09554221,2.794999549,-1.194504732,-1.65236911,-1.279617973,-1.01912767,-1.091874306,-0.929534599,-4.003958445,-1.484925377,-1463.505726675503 -3331,3331,L199H,-0.048182027,-0.011434148,-0.038469085,-0.00428956,-0.004857554,-0.019914162,-0.070689457,-0.025674596,-0.040655466,0.006449249000000001,-0.029317543999999997,-0.022970801000000002,-0.053967367999999995,0.025123883,-0.033703002999999995,-0.001196203,-0.008518904,1.671448915,3.643209181,-1.522307787,-1.233090714,-1.216145424,-1.621006851,-1.369052811,-2.172243134,-4.080918322,-1.343540111,-1457.7586470344104 -3332,3332,L199K,-0.082210785,-0.009505674,-0.055498447,-0.078800065,0.048501145999999995,0.090858671,-0.09417493099999999,-0.070246638,-0.037324705,0.027943466,-0.046954814000000004,-0.075362003,-0.035634891,0.003913019,-0.161513149,0.036707647,0.060294645,1.068847326,2.622453332,0.45010658299999995,0.48516745,0.662854179,0.447277229,0.7473067170000001,-0.09207266199999999,-2.620869448,1.3826207940000002,-1456.4060322977602 -3333,3333,L199M,-0.033186398,0.030030665,-0.030539012,0.011792131,0.041551904,-0.030350807,-0.032512778,-0.033860018,-0.017546557,0.08883072,-0.028769391000000002,0.002586035,-0.06366405900000001,0.02957501,-0.005990749,0.1191808,-0.036076992999999995,1.13745858,3.037313811,-1.271333499,-1.49349955,-1.249699219,-1.10516378,-1.402469414,-1.105835533,-4.45667329,-0.923037538,-1465.183505340945 -3334,3334,L199N,-0.022179942999999997,-0.089026972,-0.059748345999999994,-0.08612693699999999,-0.10430702300000001,0.009643383,-3.01e-05,-0.044329785999999996,-0.002429429,-0.160185085,-0.017868858,-0.113335029,-0.006161661999999999,-0.10180231199999999,-0.070451561,-0.10956398,-0.09905006599999999,1.519985004,2.40768186,-0.685409805,-0.8028242259999999,-0.517895821,-1.015296661,-0.126506271,-0.964526047,-3.8731687860000004,-0.380882008,-1457.8182871085592 -3335,3335,L199Q,-0.03683636,0.015745131000000002,-0.020020164,-0.017761958,-0.02665737,-0.015306065,-0.07681909,0.003146371,0.008164023000000001,0.02647021,0.005020051,-0.029426413999999998,-0.010613913999999999,-0.040848432000000004,0.005324516,-0.072144269,0.018829528999999998,1.255459217,2.31068285,0.20735864699999998,0.054607925,0.333608261,0.433601601,0.368667175,-0.153691727,-3.1514519589999996,0.42151381,-1461.7349703400396 -3336,3336,L199P,-0.053286605,-0.025114700000000004,-0.027665229,-0.030893432999999998,-0.013699019,0.0030036520000000003,-0.068002324,-0.038570886,0.004672419000000001,0.011357622,-0.061587021,-0.016523791,-0.038806667,-0.008906617,-0.052880249000000004,0.00829819,-0.035696227000000004,1.277305372,2.668884747,2.6072608859999997,2.125410118,2.26823056,3.014168175,2.800000595,2.82849498,-0.32526398300000003,2.628795874,-1461.3598662712611 -3337,3337,L199S,-0.033089777,-0.023175112999999997,-0.034415472999999995,-0.016419681000000002,0.004816356,-0.020471327,-0.038589716,-0.027589837000000002,0.0064249730000000005,-0.017909915,-0.02844031,-0.01681735,-0.052013595,-0.008628976,-0.024210386,0.02447777,-0.014845058999999999,1.202973848,2.612738961,0.72763315,0.434434555,0.680519577,0.7249530940000001,0.9993557209999999,0.7989028020000001,-2.285986325,0.70741059,-1456.349618810229 -3338,3338,L199R,-0.048343644000000005,-0.031977845,-0.037559973999999996,-0.028883189,-0.020615908999999998,0.002825302,-0.061342596,-0.035344692000000004,-0.004254031,-0.018456948,-0.045498742,-0.060877111,-0.014242837,-0.022052544,-0.035713833,-0.03388878,-0.007343036999999999,1.313536315,2.5357030959999998,0.222702208,0.45985980200000004,0.05245153,1.133191315,0.219049904,-0.751041512,-3.231284381,0.701463356,-1450.9552687359974 -3339,3339,L199T,-0.030411367,-0.018536086,-0.045893348,-0.007034096,0.004982805999999999,-0.007393435,-0.025793228999999997,-0.035029505,0.03159419,0.00592441,-0.042996581,-0.039581106,-0.05220559,0.036954581,-0.051022773,0.019113566000000002,-0.009147954,1.151316067,2.60658435,0.39018359799999996,-0.157049606,0.325246689,0.56849118,0.676636864,0.537592865,-2.025771979,0.346320251,-1460.0425810855813 -3340,3340,L199W,-0.015509895,0.0028160790000000004,-0.016694373000000002,0.00904024,-0.034159285,-0.005438928000000001,-0.011210651,-0.019809139,0.019608237,0.000505217,0.0051269409999999994,0.0040118770000000005,-0.037400623,-0.025688593,0.043769073,-0.014400561000000001,-0.053918007999999996,1.152331745,2.430418174,-3.1182080869999997,-2.865300835,-2.951775208,-3.251074608,-3.0064635089999996,-3.516426277,-6.185233166000001,-3.027377113,-1464.1698675351217 -3341,3341,L199V,-0.045907332,-0.011172241000000001,-0.05700909,-0.02239062,-0.018299501,0.025046952,-0.045953977,-0.045860686,-0.009813985,0.025448538,-0.04779302,-0.083369994,-0.030648186,-0.009151973,-0.035629266,-0.01427887,-0.022320131,1.2473635490000001,2.50703257,0.334227567,-0.22086610399999998,0.020062904,0.506673843,0.35527419299999996,1.009992996,-2.161832686,-0.230118011,-1465.7888467963785 -3342,3342,L199Y,-0.026289551,-0.054758716,-0.076301005,-0.10372038199999999,-0.046826307000000005,0.011961406,-0.028762876,-0.023816225,-0.07809968099999999,-0.057563183,-0.051954248,-0.097048491,-0.055553517999999996,-0.10891221699999999,-0.098528547,-0.10149302,0.007840406999999999,1.377105667,2.234997027,-1.6982812319999998,-1.8146072009999998,-1.286404877,-2.148637505,-1.1045009540000001,-2.137255623,-4.591965463,-1.4534543869999998,-1463.3325290391222 -3343,3343,A200C,-0.026611937000000002,0.047657519,0.034244771,0.057625989,-0.053922218,0.014591848000000001,-0.056806994000000006,0.003583121,0.055491137,0.09628950800000001,-0.00097447,0.10137096599999999,-0.032881424,0.074326689,0.040925289,0.036042915,-0.14388735,1.1102709990000001,2.803064708,-6.33652859,-6.165485382000001,-6.927766411,-6.331905533,-5.913112807999999,-6.344372817999999,-7.559379047,-6.191135922000001,-1463.412258320488 -3344,3344,A200E,-0.029374586,0.025307142999999997,-0.039179385,-0.028328869,-0.011045613999999999,0.027760609,-0.032732952,-0.026016219,0.081445845,-0.02096752,0.071581805,-0.015283969,-0.0630748,-0.002189434,-0.054468304,0.000189394,-0.022280621,1.300420265,2.768342995,-2.06435992,-1.507211639,-2.639424301,-2.996210167,-1.231242271,-1.94771122,-3.7363885569999997,-0.262873058,-1458.4126298874617 -3345,3345,A200D,-0.070584728,-0.014830798000000001,-0.051548853,-0.000508647,-0.046943255,0.024348387000000003,-0.121569668,-0.019599788,0.11826485199999999,-0.030035781,0.000374185,-0.001506212,-0.101591494,0.031689415,-0.032706708,0.003171994,-0.097058503,1.165366601,2.63846726,-2.948624658,-2.068119225,-2.6593740230000003,-4.752940132,-2.239861061,-3.02282885,-3.4923667089999997,-0.980329441,-1458.2255256287754 -3346,3346,A200G,-0.007804846,0.006225709,0.008956813000000001,0.019080766000000002,0.01257536,0.024556248,-0.006477254,-0.009132437,0.068433832,-0.015883937,0.028335355,0.021956316,-0.004042691,0.031197249,0.006964282,0.044902977999999996,-0.019752258,1.215398119,2.910565384,-1.978299922,-2.338692245,-2.365577271,-1.4020961459999999,-1.842778946,-1.942355003,-3.992203035,-1.663032976,-1462.2837580787018 -3347,3347,A200F,-0.018269591,0.063130521,0.036109897,0.033945436,-0.236304149,0.071027026,-0.009470827,-0.027068354,0.001520594,0.060043083,0.066217958,0.036175366,0.036044427999999996,0.033693286,0.034197586,-0.208006904,-0.264601393,1.33632919,2.053517302,-5.242302884,-4.960608925,-6.154960365,-5.737094582,-4.068340485,-5.290510063,-6.155416663,-4.428297016,-1460.4068493251689 -3348,3348,A200I,-0.029431769,-0.010061659,-0.04120711,-0.014574678,-0.106340364,0.052785942999999995,-0.052675550999999994,-0.0061879859999999995,0.10357502199999999,0.008250075,-0.028373392,-0.014977156,-0.06743706299999999,0.007808784,-0.03695814,-0.089685625,-0.12299510300000001,1.538507605,2.53660855,-5.603560627999999,-5.41130365,-6.753201004,-5.8156597979999995,-4.64561525,-5.392023438,-6.260061696,-4.579612149,-1459.7492313245311 -3349,3349,A200H,-0.039130902,-0.0026757459999999997,0.01115046,0.006564284,-0.037725566,0.031114033,-0.010355144,-0.06790666,0.10825227400000001,-0.034216091000000004,0.028864599999999997,-0.048207072999999996,0.070507992,-0.016409016000000002,0.029537584,-0.039301588,-0.036149543,1.308833034,2.463800836,-3.2820957,-3.2462351760000003,-3.498612625,-3.588377975,-2.1990896,-3.878163124,-4.624581411,-2.955316012,-1458.4465795876458 -3350,3350,A200K,-0.046845057,0.057763844,0.04576431,0.08728239900000001,0.018088694,0.046833127999999995,-0.063053213,-0.030636901,0.082408805,0.080072716,0.035454971,0.111316635,-0.019788015,0.190675445,-0.016110648,0.110181067,-0.074003679,1.190057792,2.955570893,-1.4770100830000001,-1.312795235,-2.202541344,-1.82094339,-0.155411606,-1.893358841,-2.830076528,-1.282424531,-1460.312379684765 -3351,3351,A200M,-0.026123703999999998,-0.08255014,-0.003295781,0.011973399,-0.146867379,-0.018347889,-0.032214754,-0.020032654,0.047360281,-0.09884783300000001,-0.066252447,-0.014977156,0.008385595,-0.014467611000000002,0.038414409,-0.15853816099999998,-0.135196597,1.4590584169999998,2.24694427,-5.356369023,-5.305223801,-6.302295021,-5.559234153999999,-4.548955055,-5.066137085,-6.45680444,-4.702264092,-1461.7544902064838 -3352,3352,A200L,-0.0019330220000000002,0.02798274,0.030829616,0.034769545,-0.12438273300000001,0.214731182,0.02344186,-0.027307902999999998,-0.069044221,0.015051492,0.040913987,0.02127924,0.040379992,0.02578114,0.043757949000000004,-0.11692251,-0.131842955,1.425823516,2.354397789,-4.361027431,-4.179353676,-5.614958961,-4.580447685,-3.1347534560000003,-4.295623375,-5.62626058,-3.46046372,-1456.7389849135652 -3353,3353,A200N,-0.011494978999999999,0.052525012,0.041116671,0.078990531,0.02956398,0.021742547999999997,-0.04373457,0.020744613000000002,0.071085774,0.070103069,0.034946955,0.075302278,0.006931064,0.114835931,0.04314513,0.013645377,0.045482583,1.110969013,2.691206778,-2.879820033,-2.288303352,-2.74953141,-4.123475548,-2.473652351,-2.764137505,-4.640253976,-2.380705622,-1462.6086246874183 -3354,3354,A200Q,0.050251820999999995,-0.020079153,0.013416539,0.001007609,-0.005148779,0.031591423,0.068517009,0.031986632,0.061461126,-0.055616365999999993,0.01545806,-0.030280843999999998,0.057113921,-0.008950219,0.010965436,-0.014741093,0.004443535,1.36370701,2.6209023940000002,-1.920512555,-1.749687454,-2.592502975,-1.898997017,-1.17666391,-2.184711418,-4.013512981,-1.596853708,-1462.039868418593 -3355,3355,A200P,-0.028145702,-0.015341938000000001,0.001648625,0.003219712,-0.031745666,0.039133998999999996,-0.029668739,-0.026622664,0.062842462,-0.022248584,-0.008435291,0.009600264,-0.006303015,0.006131646,0.000307778,-0.007101108,-0.056390222999999996,1.132273025,2.457200025,-2.215237064,-2.620083817,-2.587442162,-2.71604171,-1.61091188,-1.54170575,-3.194475992,-0.9909762679999999,-1459.6134956022725 -3356,3356,A200S,0.005234763,-0.02556681,-0.005082739,-0.000237133,-0.014845208,0.012398618,0.003561638,0.006907887,0.034065912000000004,-0.04798591,-0.00314771,-0.010515301000000001,0.000349824,-0.013959346999999999,0.013485081999999999,-0.018194692,-0.011495723000000001,1.6804900280000001,3.618873133,-0.49237164899999997,-0.543315247,-0.429975334,-0.618816551,-0.4020019,-0.46774921399999997,-2.68976813,-1.039618749,-1459.9090285045095 -3357,3357,A200R,0.004946159,-0.003826467,0.022129448,0.03527823,0.021184161,0.025017957,0.0016853410000000001,0.008206976999999999,0.048385631,-0.015124918000000001,0.007471985,0.023881648999999998,0.020377247,0.044994510999999994,0.025561947999999998,0.035558831,0.00680949,1.121916643,2.79062175,-2.107368005,-1.7078536830000002,-2.768899689,-2.106760689,-1.272521233,-2.680804733,-3.268198941,-1.3884089080000002,-1455.8552460600622 -3358,3358,A200T,-0.003696762,-0.007576229,0.017188402,0.020583766,-0.004445483,0.027038771,-0.006686813000000001,-0.0007067110000000001,0.047373247,-0.020707154,0.005554697,0.025972076,0.008404726999999999,0.032392366,0.008775165,0.008876496,-0.017767462,1.229262094,2.64094817,-1.4326009219999998,-1.500982338,-1.825462746,-1.3863909909999999,-1.029659264,-1.42050927,-2.659399263,-1.610479948,-1461.8358936593868 -3359,3359,A200W,-0.044046295,-0.012560905,-0.017588727,0.009104568,-1.124258477,0.057042598,-0.02910655,-0.05898604,0.003531155,-0.029761749,0.00463994,-0.00174889,-0.033428564,0.010881288000000001,0.0073278480000000005,-0.9201957590000001,-1.328321195,0.718093897,1.3671650780000002,-6.036016387999999,-6.064901756,-6.236705299,-6.485004654,-5.147675331,-6.245794899,-6.720253791,-5.111194655,-1457.711814966984 -3360,3360,A200V,-0.007062774,0.050735117999999996,0.020328242,0.025989164,-0.017479696,0.02233301,-0.011824362,-0.002301186,0.021825551000000002,0.08478989099999999,0.016680344,0.053025882999999996,-0.012369399,0.05095116,0.001027168,-0.005128624,-0.029830767999999997,1.543610422,3.106887046,-3.676340923,-3.1961958310000003,-4.759832581,-3.9991542589999995,-2.914144051,-3.512377892,-4.810783426,-2.7948060710000004,-1460.0160315339454 -3361,3361,A200Y,-0.021652706,-0.037985166,-0.034170978,-0.024685983999999998,-0.11624887800000001,0.009581237,-0.042611712999999996,-0.000693699,0.11714216,-0.025409547999999997,-0.050560783,-0.02751886,-0.040823095,-0.024286457,-0.025085511,-0.017903685,-0.21459407100000003,1.232115325,2.429077035,-4.867099884,-4.744533501,-5.629223709,-5.517648353999999,-3.2367213130000003,-5.207372543,-5.581615655,-3.710639922,-1458.3718417184427 -3362,3362,S201A,0.058912639,0.075785461,0.035453647000000005,0.011202742,-0.031490122,0.034466881,0.062018142000000005,0.055807135,0.054150194000000006,0.058552512,0.09301841,0.045320039000000006,0.025587254,0.008957839,0.013447645,-0.015205865,-0.047774379000000006,1.136862586,2.473260191,-5.015778911,-4.525545143,-5.794193358999999,-6.027866684,-3.889876305,-4.841413063,-3.940772615,-0.96982833,-1455.374944803305 -3363,3363,S201C,0.080602776,0.10764683,0.043359389000000005,0.042955041,-0.840956088,0.143920691,0.128008641,0.03319691,0.047132176,0.027955272000000003,0.187338387,0.084618531,0.002100247,-0.018510915,0.104420996,-0.550014685,-1.131897491,0.8437788940000001,1.4927084830000001,-10.68418734,-10.89577136,-11.67805361,-11.63821697,-9.82550769,-9.383387054,-8.622655714,-5.1785485289999995,-1460.990450641606 -3364,3364,S201E,0.04842020599999999,0.008935469,-1.267088602,-2.261866755,-2.7645417219999997,0.096039068,0.075155531,0.021684881,0.042426881,0.020594172,-0.002723235,-1.292488377,-1.241688827,-2.182680679,-2.341052831,-2.933691983,-2.59539146,0.520758176,0.061040860999999995,-8.518540659,-5.967336609,-8.74648597,-11.33289661,-7.82415863,-8.72182547,-5.1283255819999995,-2.179564379,-1445.8055015946738 -3365,3365,S201D,-0.006148843,0.029843457,-0.450277439,-2.168001972,-2.588748537,0.0054701030000000005,0.001304935,-0.01360262,-0.028970281,0.034047223,0.02563969,-0.355875355,-0.544679523,-2.388735161,-1.9472687819999999,-2.139746465,-3.0377506089999997,1.0867144709999998,0.47962756700000003,-7.512343587999999,-5.828881813,-6.848253028999999,-9.755699974,-7.842187416,-7.286695709,-5.30612809,-1.700953039,-1452.786543885246 -3366,3366,S201G,0.035568879,0.057968918,0.015578802,0.002437304,-0.06664576900000001,0.053234026,0.027449603,0.04368815400000001,0.017634112,0.026937261,0.089000575,0.022748163,0.008409441,-0.022269274,0.027143881,-0.063387213,-0.069904324,1.2166231140000001,2.35890501,-7.449653735,-8.414598816,-6.847459137,-8.450563751,-6.298477432,-7.23716954,-5.764700047000001,-2.667625788,-1451.567060408648 -3367,3367,S201F,0.049190227999999996,0.07344990900000001,0.005042318,-0.956098951,-1.8746631130000002,0.09315016,0.059160091,0.039220364,0.002650112,0.038538416,0.108361402,0.000297645,0.009786991,-0.853830805,-1.058367096,-1.860114614,-1.889211612,2.179448238,1.598394009,-11.806322699999999,-13.51024082,-13.92246842,-11.48317596,-11.7319626,-8.383765694,-7.689822272000001,-4.459539285,-1456.777578418143 -3368,3368,S201I,-0.031273503,0.047907902,-0.065810406,-1.671864169,-2.5441557280000002,0.108963508,0.014411825,-0.07695883099999999,0.019731305,-0.0018569320000000002,0.097672735,-0.042167276,-0.089453536,-1.9283196,-1.4154087380000002,-2.156452159,-2.931859297,0.908308158,0.674327355,-12.98294311,-13.72494852,-15.29630914,-14.48760004,-10.34980784,-11.05605002,-7.5943017489999995,-3.9026653639999997,-1449.0605173693039 -3369,3369,S201H,0.151057406,0.138598553,0.089693922,0.08745704300000001,-0.334359694,-0.051183623,0.018405424,0.283709387,-0.027610986,0.195774005,0.08142310000000001,0.121573545,0.057814298,0.10711013800000001,0.067803948,-0.228312452,-0.440406936,0.8400508809999999,1.7109388330000002,-9.094187946,-10.76593639,-9.384600571,-10.22636851,-7.560330337999999,-7.533703918,-5.620228354,-2.196514976,-1453.2800019267015 -3370,3370,S201K,-0.092811746,-0.009571605,0.03806445,-0.014802606000000001,-1.509409538,0.13352033,-0.022517407000000003,-0.163106085,0.034601543,0.055016747000000005,-0.074159957,0.080747837,-0.004618937,-0.006525528,-0.023079682999999997,-1.25608503,-1.7627340459999998,0.700254982,1.335633859,-10.64617295,-8.505343575,-12.51777921,-13.39937077,-7.897706337000001,-10.91066483,-6.048756889,-2.108589629,-1456.5517677236348 -3371,3371,S201M,0.009987963,0.12574861199999998,0.069701232,0.066017724,-0.147038285,0.043895555,0.048647055999999994,-0.02867113,0.029837752999999998,0.139615226,0.111881997,0.12446441,0.014938053,0.092686285,0.039349162,-0.10118307,-0.192893499,1.1185417359999998,2.212869614,-12.07658529,-12.37099459,-12.22245094,-14.02111259,-9.893419159,-11.87494916,-7.519496413,-3.824881271,-1455.203259086702 -3372,3372,S201L,0.045287467000000005,0.10275679900000001,0.054844124,0.02906642,-1.396292631,0.12953978300000002,0.040121781,0.050453153,0.036773397,0.075733858,0.12977974,0.08470503800000001,0.024983209,0.016383837,0.041749003,-1.139869862,-1.6527154,0.65336427,1.3387569940000001,-11.35795939,-12.32415085,-11.89856492,-14.03701805,-9.584003433,-8.946059715,-6.858910255,-2.348337164,-1448.1501836339012 -3373,3373,S201N,-0.071533666,-0.005406604000000001,0.021706694,-0.025106682,-0.239890997,0.029382441000000002,-8.87e-05,-0.142978631,0.070576763,-0.08855029699999999,0.07773709,0.029730918,0.013682469,-0.011246778,-0.038966586,-0.131945364,-0.34783663,1.4658252630000002,2.323398534,-6.735959922999999,-6.675410995,-6.131783165,-9.093244171,-5.93486322,-5.844498062,-5.37557227,-2.6193096540000003,-1458.052362860646 -3374,3374,S201Q,0.033885989,0.088679825,0.038422615,0.04016824,-1.569776964,0.079417324,-0.009216911999999999,0.076988889,0.110109888,0.10731961,0.070040039,0.08345733799999999,-0.0066121090000000006,0.113008568,-0.032672089,-1.3993837759999999,-1.7401701509999998,0.435615855,1.312020926,-9.63957339,-8.279954117,-10.93554783,-12.57107229,-7.666596687,-8.74469603,-5.7993409620000005,-1.78087795,-1448.863624884747 -3375,3375,S201P,0.024611212,0.021190739,-0.019472077,-1.613393625,-2.184156114,0.035446489,0.0247691,0.024453324,0.032469592,0.013437682,0.028943795,0.006980343000000001,-0.045924495999999995,-1.5780653969999998,-1.648721852,-2.312989881,-2.055322346,0.646431506,0.6969314940000001,-10.050775699999999,-9.229124176000001,-12.16369623,-9.80280497,-9.063842079,-9.994411026,-7.84256926,-4.747873306000001,-1454.3929457236081 -3376,3376,S201R,0.005019381,0.042968997,-0.004749115999999999,-0.01867951,-1.3981916840000002,0.141787874,0.010544136,-0.000505375,-0.00453762,0.004248656,0.081689338,0.005481418,-0.01497965,-0.025375047999999997,-0.011983971999999999,-1.195087573,-1.601295794,0.590299237,1.3305155659999999,-11.56515545,-10.14757697,-12.11717044,-15.22759116,-9.116005898,-11.21743277,-6.59070918,-2.818470642,-1456.450600404758 -3377,3377,S201T,-0.009666123,0.016144153999999997,0.021141023,0.009639763,-0.745591461,0.030912736,0.018662416,-0.037994661,0.002343965,-0.009024187,0.041312494,0.014352998,0.027929047000000002,-0.00453169,0.023811216,-0.524030928,-0.9671519940000001,0.798774203,1.4656054219999999,-5.781961555,-5.82442691,-6.10699894,-7.266625259,-3.982652672,-5.729103996,-5.585314202999999,-2.800630659,-1451.6700627412647 -3378,3378,S201W,0.00033607099999999996,0.023022663,-0.07044711099999999,-1.6413638640000001,-2.368502358,0.112515205,0.013499097,-0.012826956,-0.043266869000000006,-0.00496738,0.051012706,-0.030078924,-0.110815297,-1.537154994,-1.745572734,-2.3673475440000002,-2.369657171,0.8298883979999999,0.7113701440000001,-13.02165139,-13.713422099999999,-13.98080469,-15.27960901,-11.01376413,-11.12065701,-8.00235837,-4.83075208,-1458.530099793803 -3379,3379,S201V,0.018122688999999997,0.048866355,0.04137407,-1.0754517829999999,-1.9466466830000002,0.056253988,0.024981233999999998,0.011264143,0.038062075,0.03518336,0.06254935,0.05305145,0.02969669,-0.862389599,-1.288513966,-2.046370194,-1.846923172,2.129355032,1.5136838119999998,-11.15350388,-10.95374879,-13.63205905,-12.67400446,-8.002326874,-10.50538023,-7.173079853,-2.609197494,-1448.6483935653232 -3380,3380,S201Y,0.031201891000000002,0.048717215999999994,0.029395108,-0.18720972,-1.529393499,0.066987247,0.020020949,0.042382832999999995,0.025314572,0.015777993,0.081656438,0.06843177,-0.009641554,-0.137779257,-0.236640182,-1.4554585780000002,-1.60332842,1.032613574,1.355593448,-10.9954052,-13.73526484,-12.74059484,-10.57682082,-9.244829674,-8.679515816,-6.862942652,-2.2879284490000003,-1459.7316005439498 -3381,3381,R202A,0.01412703,-0.000811593,-0.005240613,-0.02549675,-0.08994603400000001,0.040802496,-0.003522963,0.031777022,0.0072043409999999995,-0.004250396,0.00262721,0.004093616,-0.014574841000000002,-0.031601969,-0.019391531,-0.09381667199999999,-0.086075396,1.25470461,2.245114357,-3.143709715,-3.393623505,-2.470641785,-3.194128731,-3.2261126019999997,-3.4340419539999996,-3.5962210669999997,-2.359906498,-1446.7479535611346 -3382,3382,R202C,0.006926441,-0.050696322,0.000581859,-0.010223511,-0.408126146,0.058954520999999996,-0.0018844999999999999,0.015737382,0.07982787,-0.018175298,-0.083217346,-0.035212167999999995,0.036375886,-0.0062069080000000006,-0.014240113,-0.253535791,-0.5627165,1.416430235,2.051316254,-5.566402192999999,-4.96781855,-4.8644205860000005,-8.126653206,-5.075690346,-4.797428276000001,-4.566229375,-1.512302667,-1455.5829394664615 -3383,3383,R202E,-0.0154208,0.054178754,0.035395489,0.055632887,-0.795980403,0.081401893,0.023731557,-0.054573156,0.016449105,0.024734857000000002,0.08362265099999999,0.007460965999999999,0.063330012,0.03326819,0.07799758400000001,-0.516176957,-1.075783849,0.683549567,1.430067376,-5.125272863999999,-4.620369392,-6.0775670470000005,-5.316691276999999,-4.090544502,-5.5211921010000005,-5.687659357,-5.009680595,-1453.060248119291 -3384,3384,R202D,-0.030420987000000003,0.018399312,-0.267550214,-1.7786013459999999,-2.503355296,0.060336771,0.004416127,-0.065258101,-0.036788382,0.034709447000000004,0.0020891770000000002,-0.166824492,-0.368275936,-1.741523432,-1.8156792590000002,-2.660499191,-2.346211401,1.010177622,0.70230544,-6.606283137999999,-4.8410265269999995,-7.010227173,-7.2047932889999995,-6.05703141,-7.918337287999999,-6.190203611,-2.690020938,-1456.0268357763998 -3385,3385,R202G,0.011607758000000001,0.002257947,-0.004669171,0.024751007000000002,-0.6735225,0.077376177,0.017229799,0.005985717,-0.005079558,0.001114177,0.0034017170000000003,-0.013861317,0.004522976,-0.004447073,0.05394908599999999,-0.505861574,-0.841183425,1.183847163,1.634563121,-4.948853743,-3.646416641,-5.11080011,-5.81868956,-4.664818657,-5.503543747,-4.912314148,-3.200783654,-1449.5378617336974 -3386,3386,R202F,-0.022245763999999998,-0.057054902000000005,0.031047635,-1.334794474,-2.154417167,0.019867033,0.003350029,-0.04784155599999999,-0.05531621900000001,-0.042482571,-0.071627233,0.046700584,0.015394685,-1.1849213140000001,-1.484667634,-1.876098992,-2.432735341,2.657613778,1.878963964,-9.169605334,-7.242079352999999,-7.613571587000001,-12.53218848,-8.225723801000001,-10.23446345,-6.1067378020000005,-4.441405817,-1451.2870408566669 -3387,3387,R202I,-0.043907101,0.093036045,-0.013478811,0.12176351,-1.284960855,0.097353712,0.00643359,-0.094247792,-0.036102293,0.150102866,0.035969223,0.120219857,-0.147177479,0.137654398,0.105872621,-0.847585835,-1.722335875,0.420078286,1.3380693259999998,-7.31711071,-6.522624886,-8.191107018,-8.09058799,-6.342393509,-7.438840149,-6.846519519,-5.937942989,-1441.8114034333266 -3388,3388,R202H,-0.02993092,0.0029465859999999997,-0.004596067,0.037142847,-1.331543416,0.04904212,0.058164222,-0.118026061,0.013199948000000001,-0.032721776,0.038614947000000004,-0.015418448999999999,0.006226316,0.033113832,0.041171862000000004,-1.155349213,-1.507737619,0.666225592,1.338910085,-5.483851369,-4.111887909,-5.52233046,-6.865654342999999,-5.221072975,-5.698311157000001,-5.838667847000001,-3.2260564869999997,-1455.6930830231868 -3389,3389,R202K,-0.096902314,-0.051238245,-0.021766922999999997,0.015281343999999999,-0.042276035,0.02085543,-0.018707428999999998,-0.175097198,0.011375178,-0.051009294000000004,-0.05146719599999999,-0.077754846,0.034221001,-0.039212684,0.069775372,-0.024038404,-0.060513665,1.2941672290000001,2.486212468,-2.422831239,-1.1089911190000001,-3.492876663,-3.9416515430000003,-1.7937369230000002,-1.776899948,-3.75523613,-2.27604613,-1454.4020591224544 -3390,3390,R202M,-0.044682358,-0.030387697,-0.032367162000000005,-0.013713747,-0.8584954359999999,0.066653431,-0.043191797000000004,-0.04617291900000001,-0.06049033,-0.000389975,-0.060385417999999996,-0.030751808999999998,-0.033982515,0.007771079,-0.035198572000000004,-0.699078097,-1.017912774,0.659798511,1.3888880630000002,-7.316168536,-6.8467518620000005,-7.925272644,-8.391896332,-6.735524017,-6.6813978270000005,-7.172639258999999,-5.824200377,-1444.172417099122 -3391,3391,R202L,-0.021061742999999997,-0.014458604,-0.008090436999999999,-0.00638522,-1.542524433,0.06586951099999999,0.014186502,-0.056309988,-0.024472485,-0.024889261,-0.0040279470000000005,-0.054630085,0.038449212,-0.065750314,0.052979875,-1.5365244830000002,-1.5485243819999999,0.7400946709999999,1.3224086609999999,-4.978351216,-5.086270103,-5.26750959,-6.302969719,-3.755172295,-4.479834373,-4.893438468,-3.618671373,-1436.9958503288217 -3392,3392,R202N,-0.071425063,0.033159054,-0.026066332,-0.032485634,-1.1257120040000002,0.07004442799999999,0.004014958,-0.146865084,0.020111942,0.040355628,0.025962479,-0.051371691,-0.000760972,-0.097031576,0.032060309,-1.025953446,-1.225470562,1.1274939590000002,1.435877865,-6.624979776,-4.916043961000001,-7.356681992,-8.128961685,-5.716518875,-7.0066923679999995,-5.8422385629999996,-3.77373789,-1452.9306630105712 -3393,3393,R202Q,-0.051652413,0.015231446000000001,0.012189075,0.06943881,0.057127195,0.060328115999999994,-0.001253854,-0.10205097099999999,-0.001468039,0.030513691000000003,-5.08e-05,0.055108040999999997,-0.030729892,0.09684502,0.042032599999999996,0.067910187,0.046344202,1.145901112,2.997685945,-1.0078154190000002,-0.904976227,-1.662644363,-0.877229774,-0.780896545,-0.813330185,-1.251869208,-2.1452390830000003,-1456.2906001587398 -3394,3394,R202P,-0.023292233,-0.12355947,-1.3973286459999998,-2.156212099,-2.418157231,0.068733222,-0.012480873,-0.034103593,-0.019879952,-0.067160867,-0.179958073,-1.460639711,-1.334017581,-2.2582056759999998,-2.054218521,-2.411264641,-2.425049821,1.065967675,0.08710478699999999,-8.711130405,-7.518736511,-8.668003113,-9.953651321,-8.313440643,-9.101820435,-7.357731992000001,-6.2391923579999995,-1451.8945023086853 -3395,3395,R202S,0.0037588590000000002,-0.007672941,-0.024271495,0.028694031000000002,-0.014030269,-0.008757108000000001,-0.021484748999999997,0.029002467,-0.01161889,0.013851291000000002,-0.029197172999999996,0.0037107359999999996,-0.052253725,0.027214171000000002,0.03017389,0.032641269,-0.060701806,1.2554882040000002,2.703136383,-3.781878111,-3.601074783,-3.083462425,-5.03497628,-3.562832382,-3.627044685,-4.265002482,-1.328426158,-1452.3068325519562 -3396,3396,R202T,0.050548777,0.005683138000000001,0.020885276,0.046270422,0.00892554,-0.017228356,0.028174107,0.072923447,0.0006223,0.025754604,-0.014388328,0.030247961,0.011522591,0.069065661,0.023475182,-0.0018610089999999998,0.019712088,1.16690635,2.709238972,-4.164589081,-4.599557068,-4.254107552,-5.118462105,-3.998667336,-2.8521513439999997,-3.917276668,-1.290255895,-1450.9666251810268 -3397,3397,R202W,-0.013977276,0.0056657769999999994,0.022085437000000003,-1.296770303,-1.8199536530000002,0.064905163,-0.001425075,-0.026529476,-0.016357345,-0.014804226,0.026135778999999998,-0.039763359,0.083934232,-1.232345964,-1.361194641,-1.943045781,-1.696861524,2.786717393,1.944826365,-9.572027321,-7.800009032999999,-8.90658329,-11.88532306,-8.834569626,-10.433651600000001,-7.96267538,-6.646083331,-1455.2577015790157 -3398,3398,R202V,0.051220642999999996,0.025211981,0.027117562,0.064059265,-0.350332115,0.045431757,0.056369128,0.046072157,-0.020021501,-0.005074795,0.055498755999999996,0.023632812000000003,0.030602311,0.036729349,0.09138918,-0.293640805,-0.40702342399999997,1.5423954469999999,2.114257004,-6.368198099,-6.174617279,-7.338235451,-6.935490776,-5.815925377,-5.576721611,-6.061554855,-5.1540494180000005,-1442.9977889694273 -3399,3399,R202Y,-0.035421283,-0.07277083599999999,-0.015233298999999999,-0.115584596,-1.6885561080000002,0.041978715,0.035309901,-0.106152466,-0.035929025,-0.08203182,-0.063509852,-0.058960567,0.028493968999999997,-0.096448649,-0.134720542,-1.954229948,-1.4228822680000002,1.022293024,1.312197351,-9.124646787,-6.233295227,-8.959063087,-12.34860015,-8.319675156,-9.762600311,-6.397831888,-3.317259661,-1445.3154544630088 -3400,3400,Q203A,0.009047373000000001,-0.08521632300000001,-0.06072866,-0.054389064,-0.133863722,0.033598062000000005,-0.003634285,0.02172903,-0.007569052,-0.101486249,-0.068946396,-0.09474456699999999,-0.026712752000000003,-0.11475513,0.0059770019999999995,-0.177008959,-0.090718485,1.4935933769999998,2.194152543,-0.8910614990000001,-1.131567566,-0.6918096690000001,-0.421077614,-0.38278298200000005,-1.828069664,-2.817035642,0.932136052,-1460.7001339206472 -3401,3401,Q203C,-0.013707403,-0.130153166,-0.082641422,-0.074973065,-0.363158022,0.003662383,-0.018307791,-0.009107015,0.06219104599999999,-0.155197969,-0.10510836300000001,-0.198538678,0.033255834,-0.18838121100000002,0.038435082,-0.38079633799999996,-0.34551970600000004,1.943210211,2.2745883030000003,-5.966348708,-6.534026122999999,-6.0253395770000004,-5.377712235,-5.32257222,-6.5720933839999995,-7.118625797999999,-4.394582485,-1454.9927832228132 -3402,3402,Q203E,-0.02997642,-0.079687865,-0.080524006,-0.06036529,-0.111883842,0.045276058,-0.036334364,-0.023618475,0.034983566,-0.053542850999999995,-0.105832878,-0.11070182099999999,-0.050346191,-0.11877780800000001,-0.0019527720000000002,-0.124756862,-0.099010822,1.506535559,2.276828753,-1.003602013,-1.036028091,-1.481996605,-0.682539375,-0.219239693,-1.598206299,-3.183675062,0.658194204,-1463.042693132069 -3403,3403,Q203D,0.080964106,-0.042763964,-0.02043459,-0.031599992,-0.137649048,0.045961942,0.131839123,0.030089087999999996,-0.008348654,-0.108022985,0.022495058,-0.097488314,0.056619135,-0.088460669,0.025260685,-0.21394192,-0.061356175,1.4623523719999998,2.102074146,-1.799307455,-2.019856232,-2.229813545,-1.52509304,-1.051295441,-2.170479019,-3.713644791,0.574432036,-1464.3361256718636 -3404,3404,Q203G,0.036486837,-0.054660442999999996,-0.035741373,-0.018183958,-0.131112702,0.064790188,0.030634425,0.042339247999999996,-0.029020185,-0.07803711099999999,-0.031283774,-0.082384597,0.010901851,-0.073290164,0.036922248,-0.16364900400000001,-0.0985764,1.1849613209999998,1.959597826,-3.170589035,-3.94040535,-2.758094017,-2.669244461,-2.548363487,-3.93683786,-4.520227665,-1.3195342159999999,-1462.4651338439435 -3405,3405,Q203F,0.050775695,0.057530164,0.05819209400000001,0.149591527,-0.6362545039999999,0.127188514,0.05996154,0.04158985,-0.161438857,0.127578833,-0.012518505,-0.032898229,0.149282417,0.10906825699999999,0.190114796,-0.535017581,-0.737491426,0.574247118,1.3994547830000001,-6.233446756,-6.736341515,-6.103628098,-6.073323296,-4.997184792,-7.256756081,-6.872597431,-4.431291731,-1463.5175793077797 -3406,3406,Q203I,0.033669049,-0.150967654,-0.098661745,-0.091308999,-0.14345360199999999,0.083693169,0.021776978,0.045561119000000004,-0.041158311,-0.223818342,-0.078116965,-0.231767077,0.034443588,-0.170242489,-0.012375509,-0.24432454899999997,-0.042582655,1.661575686,2.183431724,-4.250835226,-4.97158136,-4.244836739,-4.478042816,-3.4337146610000002,-4.126000557,-5.24660358,-3.016086192,-1456.0974263167009 -3407,3407,Q203H,0.143710879,-0.040920946,-0.049029882000000004,-0.020392405,-0.10444893400000001,-0.012674969,0.141499942,0.145921816,0.006565066,-0.14352738199999998,0.061685490999999995,-0.181579989,0.083520226,-0.12293714900000001,0.08215234,-0.22785947199999998,0.018961604,1.82105828,2.3667080780000003,-3.055767175,-4.264850128,-2.8118556210000003,-2.532133087,-2.351622353,-3.318374687,-4.773509707,-2.074518811,-1459.4231833321974 -3408,3408,Q203K,0.074298141,-0.118643304,-0.012686892,-0.021654338999999998,-0.062261928,-0.043195069,0.053122115,0.095474167,0.010777712,-0.208361391,-0.028925217000000003,-0.09829256300000001,0.07291878,-0.067150604,0.023841927000000002,-0.088274745,-0.036249111,1.23689761,2.201551701,-1.064063065,-1.548339577,-0.986165359,-0.822657669,-0.818102448,-1.14505027,-2.543776781,-0.338444146,-1455.3067153310403 -3409,3409,Q203M,0.104041635,-0.10142385599999999,0.012983266,-5.21e-05,-0.063881637,-0.044808457999999995,0.084320886,0.123762384,-0.011426431,-0.066096066,-0.136751645,-0.18649049399999998,0.212457025,-0.104792162,0.104687865,-0.09349272800000001,-0.034270545,1.4613129390000001,2.305370451,-4.9914325999999996,-5.667575348,-4.797605606,-5.006145424,-4.248336838,-5.237499786,-5.779285241,-3.7721852910000004,-1460.6634586472064 -3410,3410,Q203L,0.076733229,-0.019976816,-0.040596634,-0.012936268999999999,-0.16289009,0.056638306,0.077877896,0.075588562,-0.013868166999999999,-0.042928201,0.0029745690000000003,-0.08576751099999999,0.0045742429999999995,-0.087221597,0.06134906,-0.215131689,-0.11064849,1.806083444,2.414225014,-3.093569086,-4.157415283,-2.873141525,-3.2488523789999997,-2.163959915,-3.0244763260000003,-4.965731275,-1.687776709,-1459.0991609152406 -3411,3411,Q203N,-0.025825347999999998,-0.10109359400000001,-0.137055663,-0.032697742,-0.171366942,-0.02901663,0.034154276000000004,-0.085804972,-0.097281544,-0.042928201,-0.159258986,-0.234038893,-0.040072433,-0.047009061,-0.018386422,-0.17166599600000002,-0.171067888,1.441922423,2.16962819,-2.46831196,-3.4037969439999998,-2.703369385,-2.8656972730000003,-1.4302223969999999,-1.938473801,-4.05033993,-1.015616292,-1462.4010737845674 -3412,3412,Q203P,0.033892855,-0.066447601,-0.8554704,-2.029098576,-3.0028038610000003,0.065592161,0.036041841,0.031743868,-0.015156833,-0.123412189,-0.009483013,-1.00036777,-0.71057303,-2.041458198,-2.016738954,-2.733961023,-3.2716466989999997,2.202035548,0.8773569,-5.781249252,-6.24758445,-5.815714127000001,-5.790782326,-5.007389862,-6.044775497000001,-7.283458106,-4.435527223,-1464.676283115521 -3413,3413,Q203S,0.027661214,-0.081439249,-0.059361664,-0.042615,-0.125549632,0.082725732,0.024483148,0.03083928,0.036195813,-0.087182804,-0.075695693,-0.112288488,-0.006434839,-0.101622115,0.016392115,-0.17601123800000001,-0.075088025,1.61032494,2.277288853,-2.337544208,-3.2307641910000005,-2.30539698,-1.9935813830000002,-1.7107478409999999,-2.4472306440000002,-4.209973258,-0.893976655,-1457.9626078065485 -3414,3414,Q203R,0.047367775,-0.058564477999999996,-0.040398525,-0.01271324,-0.093200959,0.028179235,0.053573617000000004,0.041161932000000005,0.009154381999999999,-0.089068291,-0.028060664,-0.080336694,-0.000460355,-0.080521078,0.055094598,-0.130930249,-0.055471667999999995,1.5154231740000002,2.322853491,-1.240930949,-1.7690986180000001,-0.943542236,-0.841148483,-0.944216743,-1.706648666,-2.0736871619999997,-0.14894945,-1448.019438273739 -3415,3415,Q203T,0.016846408,-0.09639090800000001,-0.061456975999999996,-0.036453177,-0.08307937,0.06500030799999999,0.002246743,0.031446073,0.022963702000000003,-0.098486401,-0.09429541400000001,-0.127135989,0.0042220370000000005,-0.082686555,0.009780202,-0.141026881,-0.025131857999999997,1.473926935,2.233998799,-2.203119624,-2.575669037,-2.314930153,-1.7355641169999998,-1.900156723,-2.489278091,-3.804767317,-0.7283879320000001,-1460.6977621456608 -3416,3416,Q203W,0.017704225,-0.093253845,-0.046018769,-0.026184829,-0.56026314,0.072701963,0.013263212,0.022145237,-0.069141378,-0.100766478,-0.085741211,-0.122836911,0.030799373999999997,-0.10973053199999999,0.057360874000000006,-0.42296483100000004,-0.6975614490000001,1.7951431480000002,2.143910843,-6.174567584,-6.76061937,-6.009993065,-5.58639698,-5.584800995,-6.931027512000001,-6.556441515,-4.693252337,-1461.9743400719017 -3417,3417,Q203V,0.045013014000000004,-0.020803282,-0.022407666,-0.019157165,-0.13953731,0.030298033999999998,0.050029845999999996,0.039996181,-0.008545371999999999,-0.016748525,-0.024858039,-0.06669460099999999,0.02187927,-0.073341203,0.035026874,-0.155023727,-0.12405089300000001,1.4744347880000002,2.227591337,-3.972264169,-4.522452782,-3.9161108319999998,-3.894717445,-3.3375336069999997,-4.19050618,-4.717166703999999,-2.5633544219999997,-1458.6380907637067 -3418,3418,Q203Y,0.005231051,-0.167024505,-0.025025798,-0.042903345999999995,-0.32455408,0.076706627,-0.040617851,0.051079953,-0.073642058,-0.18905623600000002,-0.144992774,-0.111574775,0.06152318,-0.132139639,0.046332947,-0.35948346700000006,-0.289624692,1.9660923590000001,2.348822776,-5.962945792999999,-6.675343162999999,-5.88945314,-5.817266281,-4.9687962489999995,-6.463870132,-7.136570454,-4.399146897,-1459.6444950271398 -3419,3419,Q204A,-0.009730886999999999,-0.024993151,-0.049539253,-0.034237914,-0.102016433,0.032298903,0.023037468,-0.042499242,-0.040804684,-0.077199885,0.027213584,-0.097871906,-0.001206599,-0.079614709,0.011138882,-0.142703424,-0.061329441,1.51423015,2.284770403,-6.928385054,-5.896941315,-7.806191856,-6.556190086,-8.14611496,-6.236487052999999,-6.995307368,-1.389158577,-1445.5807208567858 -3420,3420,Q204C,-0.020765872,0.029843336,-0.012705596999999999,0.076884177,-0.043050656,0.050648317000000005,-0.0072566919999999995,-0.034275052,-0.055255463,0.059440562,0.00024611,0.023202255,-0.048613449,0.130708091,0.023060262999999998,0.02928292,-0.11538423099999999,1.0639854640000002,2.8075129530000003,-10.26420583,-9.689733711,-10.22784941,-9.631563437999999,-12.12607321,-9.645809364,-8.537906429,-5.379497447,-1452.3874686891213 -3421,3421,Q204E,-0.032467208,-0.005834331,-0.033789291,-0.045914631,-0.04927128099999999,-0.01833168,0.00912238,-0.074056796,-0.07496675900000001,-0.02538629,0.013717628999999999,-0.04742465,-0.020153932,-0.0444736,-0.047355662,-0.067357532,-0.03118503,1.288020487,2.3155706240000002,-4.793254344,-4.273599579,-6.029192977999999,-4.62771769,-5.415277351,-3.620484123,-6.621755222999999,-0.828970683,-1449.0860880790278 -3422,3422,Q204D,-0.072188449,0.032241165,-0.009304158,-0.008682049,-0.441077459,0.07291431,-0.026080016,-0.11829688099999999,-0.074933015,-0.025450012,0.089932341,-0.009273544,-0.009334772,-0.024741816,0.007377718,-0.313380434,-0.568774484,1.142910796,1.76653607,-9.718823666,-9.903390457,-11.3989586,-7.914471497,-12.77802245,-6.599275322,-7.317098519,-2.7555048039999996,-1448.1960592805408 -3423,3423,Q204G,-0.037548672000000005,-0.028265931,-0.035292868,-0.177222968,-1.7868700880000001,0.10295553,-0.0049419220000000005,-0.070155421,-0.11241191800000001,-0.056335465999999994,-0.000196396,-0.070790954,0.00020521799999999999,-0.156718257,-0.197727679,-1.673550461,-1.9001897140000001,1.154406569,1.3506297630000001,-10.35932461,-9.756956596,-10.26896438,-10.12925534,-11.86313744,-9.778309303,-7.9674092839999995,-4.219445045,-1449.950421643909 -3424,3424,Q204F,-0.006789703,0.026093242000000003,-0.051287222,0.01939235,-0.770665464,0.08903114599999999,-0.000523309,-0.013056097,-0.129343457,-0.036907033,0.089093516,-0.05473879,-0.047835654000000005,-0.012382908,0.051167607999999996,-0.592134035,-0.949196892,0.965988554,1.490980685,-8.206986012,-7.236257515,-7.038316292,-5.875154564,-10.38010383,-10.50509786,-6.15695264,-0.771724835,-1451.8773037316278 -3425,3425,Q204I,0.041960461,0.006712298,0.021066124,0.042673057,0.012872343,0.050409503,0.08377113900000001,0.00014978299999999999,-0.077982089,0.061396217999999995,-0.047971623,-0.014086461000000002,0.056218708,0.043905485999999994,0.041440628,-0.024057198,0.049801883,1.299156972,2.629359607,-6.326507518,-5.364922058,-7.192080353,-6.309971375,-8.456743675,-4.308820129,-4.908510103,-1.8229333509999999,-1448.7632792936638 -3426,3426,Q204H,-0.026674787000000002,-0.0010766880000000001,-0.043184657,0.026326247999999997,-0.08535206,-0.012439457,-0.020613442,-0.032736132,-0.065528893,-0.017685659,0.015532283999999999,-0.008474308,-0.077895006,0.045499927,0.007152569,-0.044454435,-0.126249684,1.2125215329999999,2.547673376,-5.323970877,-5.303025703,-4.649339287,-3.8360319439999997,-5.896350845,-6.935106606000001,-5.174337541,-2.627184904,-1449.299328151159 -3427,3427,Q204K,0.006345465,-0.039110271,-0.07272278900000001,-0.028403328,-0.27179529199999997,-0.090846588,0.00156968,0.011121249,-0.134552449,-0.137774199,0.059553657999999995,-0.035164417,-0.110281161,-0.05561704,-0.0011896160000000001,-0.25478571899999997,-0.288804864,1.4490578580000002,2.03521767,-3.149801241,-3.731339188,-2.358207733,-3.491384727,-3.834167542,-2.333907013,-3.8468176030000003,-1.612371369,-1444.41225077305 -3428,3428,Q204M,0.013628903000000001,-0.021238912999999998,0.000480905,-0.049963987,-0.027101503,-0.03954068,0.030497981,-0.003240175,-0.002857593,-0.053638474000000005,0.011160648,-0.020586531,0.02154834,-0.04971548,-0.050212494,-0.030833844,-0.023369161,1.450314855,2.5612840080000003,-6.387218326,-5.610242935,-7.587726112,-5.772013199,-7.918727463,-5.04738192,-6.151981162999999,-2.065276824,-1451.4329812452197 -3429,3429,Q204L,0.007422384000000001,0.004814295,-0.000320769,0.021258806,0.004851927,0.0028440709999999997,0.01424432,0.0006004480000000001,-0.060463376,-0.07468988,0.08431847,-0.022114314,0.021472776000000002,0.0064159230000000005,0.036101689,-0.041269882,0.050973736,1.269526613,2.4815177409999998,-4.711900244,-4.036818321,-5.244483826000001,-4.175625587,-5.9135473560000005,-4.189026131,-3.622523234,-0.21741106699999999,-1453.1190020940267 -3430,3430,Q204N,-0.02479313,-0.027897848,0.035344717000000005,0.07143970200000001,-0.08281981,0.043573272,0.069535032,-0.11912129099999999,-0.075885732,-0.001191481,-0.054604214000000005,0.087150176,-0.016460742,0.09831152900000001,0.044567875,-0.052779095,-0.112860525,1.244192204,2.483465343,-7.790969315,-8.371457451,-7.187158455,-7.62318074,-8.955768379,-6.8172815479999995,-7.789989527,-4.281937966,-1449.1464900998399 -3431,3431,Q204P,-0.031377557,-0.001233738,-0.188287951,-1.734230786,-2.3246162999999997,0.143612099,0.014259436,-0.07701455,-0.110958578,-0.039322457000000005,0.036854982,-0.196021898,-0.180554004,-1.6661916959999998,-1.802269876,-2.151656955,-2.497575645,1.2615516420000001,0.7458076029999999,-9.012237086,-8.522665092,-9.101436501,-7.67965802,-10.08138094,-9.676044884,-7.314275267,-3.6255577010000004,-1449.2410745518282 -3432,3432,Q204S,-0.020187171,0.001088683,-0.01489269,0.036134282000000004,-0.18684614800000002,0.012153545,-0.000267164,-0.040107178,-0.086292106,-0.037127291,0.039304656,-0.008168789000000001,-0.02161659,0.049350468,0.022918095,-0.160845207,-0.21284708800000002,1.310114585,2.176296874,-7.599155696,-6.9609521029999994,-7.979813316,-7.077667099,-9.411826927,-6.565519035,-7.4839749310000006,-3.277965501,-1449.658768660389 -3433,3433,Q204R,-0.021702945,-0.00139804,-0.064459337,-0.013331497,-0.115500466,0.084304336,0.011473048999999999,-0.054878937999999995,-0.059994199000000005,-0.05537413,0.052578050999999994,-0.09796157400000001,-0.030957099,-0.032208554,0.00554556,-0.11828094199999999,-0.11271999,1.404742944,2.264955788,-3.980964052,-4.157758018,-3.682695976,-3.281483986,-4.705201057,-4.077681221000001,-4.520942915,-0.138971398,-1447.9216890162788 -3434,3434,Q204T,-0.011209562,-0.009830137,-0.070173495,-0.052257522,-0.056559810999999995,-0.034811822,0.005040955,-0.027460078,-0.04017235,-0.034790037999999995,0.015129763999999999,-0.098250134,-0.042096855999999995,-0.026179085,-0.07833595900000001,-0.077834206,-0.035285416,1.223787824,2.207505222,-5.288090616,-4.037604362,-6.353929657,-5.75799514,-6.227979462,-4.0629444580000005,-4.794205527,-1.840653195,-1451.8272390468046 -3435,3435,Q204W,-0.028799862000000002,-0.042011687,-0.041096952,-0.03338423,-1.247783737,0.11490595599999999,0.021776474,-0.079376198,-0.154134722,-0.063901217,-0.020122156999999998,-0.090569835,0.008375931,-0.04984088,-0.01692758,-0.993601002,-1.5019664719999999,1.392301564,1.544910084,-8.559796611,-8.915647606,-7.728343636,-5.590786774,-10.61903686,-9.945168182,-7.1008555829999995,-2.406676212,-1449.9028537780978 -3436,3436,Q204V,0.005264583000000001,0.021071642999999998,-0.029116932,0.008258363000000001,-0.041599533,-0.014870648,0.035987305,-0.025458138999999998,-0.08610704300000001,-0.005590092,0.047733378,-0.039594362,-0.018639501,0.013785725,0.002731001,-0.033584791,-0.04961427400000001,1.271114357,2.630115111,-6.961271057,-5.660403587,-8.026576248,-6.411172775,-9.208332321,-5.499870354,-6.137435554,-1.6237079380000001,-1451.8059856956825 -3437,3437,Q204Y,0.07924761799999999,-0.014098208999999999,-0.0087085,-0.009405432,-0.310308743,0.008972584,0.116684812,0.041810423,-0.064618127,-0.174903038,0.14670662,-0.080519597,0.063102598,-0.032792512999999995,0.01398165,-0.414486562,-0.206130924,1.2620928009999999,1.737657267,-7.758536011,-7.3733314210000005,-5.261333893,-6.9089653239999995,-9.320110069,-9.928939346,-6.29015821,-1.889148187,-1447.3775725555606 -3438,3438,L205A,0.019851063000000002,-0.015396981,-0.034639964,-1.658049225,-2.461863376,0.04322961,-0.010479931999999999,0.050182057,-0.069597491,-0.013703185,-0.017090776000000002,-0.06811091,-0.001169017,-1.670185323,-1.645913126,-2.333458432,-2.59026832,0.9366132290000001,0.706922305,-12.20451401,-12.36238978,-12.652662699999999,-10.13373679,-9.627166245,-16.24661452,-6.090057057999999,-2.594446156,-1454.3181272917427 -3439,3439,L205C,-0.019895716,-0.000569618,-0.054033073,-1.836800564,-2.875775708,0.003212922,-0.05668269,0.016891258,-0.030231242000000002,0.024367813999999998,-0.025507049,-0.046141259000000004,-0.061924887000000005,-1.8532546000000003,-1.8203465269999999,-2.8857435660000004,-2.865807849,0.66464182,0.673460125,-11.4146319,-13.57925574,-11.01678369,-10.85272196,-8.69694928,-12.92744884,-8.043977132,-5.2450627,-1461.2198281423189 -3440,3440,L205E,0.0066945730000000005,0.031572172999999995,-1.108244013,-2.3257169980000003,-2.7855108960000003,0.017666524,-0.001568135,0.014957281000000001,-0.06349039,0.062592862,0.000551484,-1.1722083559999998,-1.04427967,-2.1738963609999997,-2.477537635,-2.650082827,-2.920938965,0.569892665,0.08209052,-14.78454096,-15.90706487,-14.51110901,-13.48524332,-12.62438112,-17.39490649,-10.27267504,-10.18488361,-1460.2907341960818 -3441,3441,L205D,0.057195529,-1.082538258,-2.3786963869999997,-2.665103682,-2.7269575710000002,0.025724287999999998,0.065306561,0.049084497000000005,-0.005336975999999999,-1.263456643,-0.901619873,-2.42047082,-2.336921953,-2.4051254859999998,-2.9250818780000003,-2.4833719430000003,-2.9705431989999997,0.297380981,-0.7756981829999999,-14.92006315,-16.33820818,-14.68664388,-13.79396,-12.1979035,-17.58360016,-10.27267504,-10.18488361,-1459.2927120770328 -3442,3442,L205G,-0.004659702,-0.614059644,-2.0709843269999997,-2.479275907,-2.949099702,0.02923512,-0.0038648370000000003,-0.005454567,0.011988781,-0.594613098,-0.633506189,-2.095738725,-2.0462299280000003,-2.36918893,-2.589362883,-2.661315207,-3.236884196,1.09562683,-0.303195952,-12.82780751,-14.37696815,-12.72808591,-11.78300147,-10.88779417,-14.36318786,-7.6851408260000005,-4.9683388939999995,-1452.170204919763 -3443,3443,L205F,-0.032178969,-0.031868468999999996,-0.024513032,-0.12097301099999999,-1.8710643869999999,0.035709132000000005,-0.015095085,-0.049262852999999995,-0.066830476,-0.02863341,-0.035103527,-0.073118109,0.024092046000000002,-0.197109332,-0.044836689000000006,-1.4714181290000001,-2.2707106440000002,1.312322062,1.403767805,-5.833958481,-5.695153603,-6.216447617,-5.27031443,-5.455759476,-6.5321172789999995,-5.006244164,-2.879872603,-1456.2726693302393 -3444,3444,L205I,0.0014169329999999998,0.032587775,-0.015563045,0.037772743,-0.249558421,0.020642222,-0.022556787000000002,0.025390653,-0.005490059,0.048357742999999995,0.016817806,-0.041709645,0.010583556000000001,0.009847861999999999,0.065697623,-0.189220765,-0.309896076,1.3605178759999998,2.106268779,-5.3771602110000005,-5.3503444369999995,-5.300337196,-6.325852157999999,-5.100272621,-4.808994643999999,-5.263339158,-2.010209142,-1456.3917065481655 -3445,3445,L205H,0.006892926999999999,-0.365777736,-1.938760469,-2.60437136,-2.728694618,0.007983501,-0.016132122,0.029917975,-0.015007204,-0.35813377399999996,-0.37342169799999997,-2.214117956,-1.663402981,-2.499802618,-2.7089401019999997,-2.7029878110000003,-2.7544014239999997,0.7572956670000001,-0.338846108,-13.85371351,-14.50213554,-13.42364077,-13.16564353,-11.45053887,-16.72660886,-10.27267504,-10.18488361,-1463.194983748719 -3446,3446,L205K,0.00231367,-1.280676373,-2.182737908,-2.531614572,-2.59346846,0.079158584,0.02612741,-0.021500071000000003,-0.085210466,-1.7038005,-0.8575522459999999,-2.161844673,-2.203631142,-2.447529335,-2.615699808,-2.525775791,-2.661161129,-0.06701978900000001,-1.063933208,-14.21506142,-15.45180968,-14.16354399,-13.04528584,-11.473633900000001,-16.94103371,-10.21800695,-9.932737047,-1464.028954458423 -3447,3447,L205M,0.010868093999999998,-0.019381352,-0.020774304,-0.036893617999999996,-0.083827633,-0.0063274180000000005,-0.000503402,0.022239589,-0.08645920900000001,-0.065967239,0.027204536,-0.089442508,0.0478939,-0.014511484,-0.059275750999999995,-0.089982887,-0.077672378,1.360942417,2.332839163,-6.1927267939999995,-6.399631874,-4.48518425,-5.423384911,-7.004078995,-7.651353942999999,-5.43290365,-1.160793435,-1460.5934243337251 -3448,3448,L205N,-0.03353555,-0.313474985,-1.813753097,-2.313144758,-2.7640742719999998,0.022149444,-0.002719758,-0.06435134099999999,-0.10782980800000001,-0.305544755,-0.321405215,-1.967708911,-1.659797282,-2.2533935730000003,-2.372895943,-2.632670025,-2.8954785189999996,1.0857587020000001,-0.10720649300000001,-14.18454103,-16.19117523,-13.21128432,-13.359175,-12.20116688,-15.95990372,-10.27267504,-10.18488361,-1459.5367428809404 -3449,3449,L205Q,0.022047672999999997,0.10734009900000001,-1.0249948009999998,-2.17490146,-2.7367553489999996,0.025358406,0.005449956,0.03864539,-0.01779787,0.168251663,0.046428534,-0.9755342490000001,-1.074455352,-2.26121891,-2.088584009,-2.816586622,-2.656924076,0.48572669,0.098547005,-13.12990704,-14.51053258,-12.60570457,-12.00533751,-10.48405785,-16.04390269,-9.339040551,-7.654565728,-1459.8089701086283 -3450,3450,L205P,-0.000986359,-1.08842056,-2.155942997,-2.368604129,-2.968101119,0.041800187999999995,-0.00689488,0.004922162,0.009150973,-1.268461663,-0.908379457,-2.247406015,-2.064479978,-2.307311634,-2.4298966230000003,-2.807631779,-3.128570458,0.09530552699999999,-0.774392435,-12.94505789,-14.50835458,-13.04197619,-12.28465415,-10.63440548,-14.25589904,-8.205569201,-6.298473446,-1467.5116881038994 -3451,3451,L205S,-0.038651277000000005,-0.132195601,-1.4650643209999998,-2.336847929,-3.040917185,0.014375638999999999,-0.039953762000000004,-0.037348791,-0.032442201000000004,-0.070943296,-0.193447905,-1.547736905,-1.382391736,-2.519802444,-2.153893413,-2.966025686,-3.1158086839999997,0.788923095,0.034129325,-14.07678772,-15.98993616,-13.62148308,-13.20527725,-12.21245905,-15.35478309,-9.613457214,-7.633653738,-1457.6554639702663 -3452,3452,L205R,-0.024106147,-1.231224138,-2.217487887,-2.2882133,-3.2162640689999997,0.056269062,-0.028128808999999998,-0.020083484,-0.003659815,-1.3946145,-1.067833775,-2.250598681,-2.184377092,-2.0591620880000003,-2.5172645119999997,-2.7394685360000004,-3.693059602,-0.125109224,-0.872408836,-14.32629773,-15.834993599999999,-13.70488641,-13.23032948,-11.46053732,-17.40074187,-10.27267504,-10.18488361,-1461.9547724891454 -3453,3453,L205T,-0.026679117000000002,0.015355856000000001,-0.107506054,-1.814054746,-2.364069586,0.025617056000000003,-0.040602574,-0.01275566,-0.042783105,0.046173525,-0.015461813,-0.074705127,-0.14030698,-1.7666362290000002,-1.8614732630000002,-2.462182644,-2.2659565280000002,0.8315045090000001,0.690175068,-12.8851837,-14.61248753,-13.402792499999999,-10.50753795,-11.19986922,-14.70323128,-7.872359776000001,-5.400813818,-1458.4127373667434 -3454,3454,L205W,0.01021667,0.011621029,-0.0020935529999999997,-1.460246231,-2.016528177,0.007436162,0.00771002,0.01272332,-0.04668821099999999,0.003853154,0.019388903,-0.05220217,0.048015064,-1.291182134,-1.6293103269999998,-2.122756257,-1.9103000959999998,2.349978198,1.5167870730000002,-10.209028199999999,-10.0729953,-9.377304054,-9.86591153,-8.791057692999999,-12.93787243,-7.710166673,-6.29847324,-1459.8415414108895 -3455,3455,L205V,-0.033243199999999994,-0.031755667,-0.0050245409999999996,-0.016427207,-1.66022784,0.025295441000000002,-0.023272667,-0.043213732000000005,-0.068674316,-0.046293803,-0.017217531,-0.033196775,0.023147692999999997,-0.009280786999999999,-0.023573627000000003,-1.567239099,-1.75321658,0.6128761979999999,1.312323321,-8.101881889,-8.814419838,-8.375038361,-7.816889626,-7.402509628,-8.100551994,-5.5651819389999995,-2.22406891,-1462.7537229210138 -3456,3456,L205Y,-0.016686586,-0.0447879,-1.180967069,-2.772704446,-2.834558335,0.07702672099999999,0.024838462999999998,-0.058211634000000005,-0.102939233,-0.055303054000000004,-0.034272746,-1.124362061,-1.237572077,-2.665319228,-2.8800896639999998,-2.7435656839999996,-2.925550986,0.8841389479999999,0.123134016,-9.771314712999999,-10.02374464,-9.755913681000001,-9.328292686000001,-8.24957164,-11.49905091,-7.396978087999999,-5.64831544,-1453.6682674428448 -3457,3457,I206A,0.050049515999999995,-0.021650217000000003,0.003051636,-0.011995618000000001,-0.09558502199999999,-0.035289522999999996,0.058581323,0.041517708,0.03452531,0.022244576000000002,-0.065545009,-0.045044735,0.051148007,-0.002665701,-0.021325535,-0.16640379800000002,-0.024766245,1.604836722,2.37359826,-1.947537602,-1.9467960819999999,-2.6359751819999997,-0.7747465590000001,-1.498135376,-2.882034813,-2.419399341,-1.314093931,-1465.6882126103155 -3458,3458,I206C,0.056276688,-0.016204476000000002,0.02971354,0.00803283,-0.120373889,-0.059680889,0.045955632999999996,0.066597743,0.06031025,0.025042907000000003,-0.057451859,-0.021714567999999997,0.081141648,0.011353924,0.004711735,-0.172991332,-0.067756445,1.3759320680000002,2.17049496,-5.749617516,-4.805214844,-4.552616791,-6.325218597,-6.14028685,-6.924750496000001,-5.5584272960000005,-3.8531741889999997,-1459.9027326474898 -3459,3459,I206E,0.005228392,-0.055838723,0.000714687,-0.048548315,-0.46814960299999997,0.080354654,-0.00164332,0.012100103999999999,0.048135572,-0.007976633,-0.103700813,-0.066373716,0.067803089,-0.044947639000000005,-0.05214899,-0.43787154,-0.498427666,1.448778451,1.8568013190000001,-1.8043769790000002,-1.763144585,-1.836326523,-1.464487595,-0.900129005,-3.0577971880000003,-2.866695879,-1.321184706,-1467.486212684773 -3460,3460,I206D,-0.072856554,-0.077987448,-0.036688185,-1.4824601819999998,-2.292964037,0.009224872,-0.09249906599999999,-0.053214042,0.04916144099999999,0.022692186,-0.178667081,-0.031897236,-0.041479133,-1.146509665,-1.818410699,-2.430204099,-2.1557239740000003,0.809928908,0.74630745,-4.533380737,-4.468248474,-4.0825438,-3.473201645,-4.429447784,-6.213461982999999,-4.10272646,-2.910718723,-1466.9489837330766 -3461,3461,I206G,0.010808238000000001,-0.034531354,-0.027168147,-0.042055194000000004,-0.507712402,0.024852141,0.020925048999999998,0.000691427,0.050784152,0.027436265,-0.09649897199999999,-0.047684656,-0.0066516380000000005,-0.012505477,-0.07160491,-0.448896081,-0.566528723,1.9931695630000001,2.308482883,-4.415394609,-4.051716248,-4.246923866,-4.0531269839999995,-4.165706337,-5.559499611000001,-3.590996891,-3.2478019689999997,-1467.1640468956903 -3462,3462,I206F,0.029917627999999998,-0.068100536,-0.10071218900000001,-0.055906262000000005,-0.115699014,0.093250674,0.08088089400000001,-0.021045638999999998,0.043465694000000006,-0.055184445,-0.08101662700000001,-0.13020727,-0.071217108,-0.075577836,-0.036234687,-0.158680063,-0.07271796400000001,1.363276039,2.126731731,-5.264772165,-4.337665443,-3.2036664889999997,-6.424996765,-6.659254288,-5.69827784,-4.471984568,-2.098540891,-1455.8455069311894 -3463,3463,I206H,0.022876997000000003,-0.073986494,-0.022999822000000003,-0.051760515,-0.490274334,-0.00326561,0.023562108999999998,0.022191885,0.042754319000000006,-0.010723865,-0.137249122,-0.094826348,0.048826704000000005,-0.026899762,-0.076621267,-0.464876178,-0.51567249,1.341771563,1.761573073,-5.219966,-5.158350525,-4.2046432419999995,-5.053256408999999,-5.736261345,-5.947318481,-4.696089267,-3.2569771939999996,-1463.6791759016924 -3464,3464,I206K,-0.016521525,-0.052681132,-0.003651442,-0.018567651,-0.166908908,0.102245973,0.062402894,-0.095445944,0.076570818,0.037531549,-0.14289381199999998,0.023802915,-0.031105797999999997,0.03388351,-0.071018812,-0.142929425,-0.19088839100000002,1.339444345,2.232258039,-2.355398444,-3.101410057,-2.386978638,-2.402503037,-1.429256905,-2.456843582,-2.284658349,-0.886288148,-1467.3209779658355 -3465,3465,I206M,0.04019459,0.033615614,0.042878135,0.018242996,-0.031823082,0.030628627999999998,0.109005315,-0.028616136,0.057253978,0.14793451900000001,-0.080703292,0.036964361,0.048791907999999995,0.115393419,-0.078907427,-0.012413142,-0.051233021,1.253934922,2.705641397,-0.49143781299999995,-0.9194278109999999,-1.0555958859999999,-0.15063781,0.052233101,-0.383760658,-2.060464331,-1.233992727,-1462.0460684653372 -3466,3466,I206L,0.041972252,-0.012020969,0.0030750390000000003,-0.027907064,-0.062484205999999994,-0.012539835,0.039540011,0.044404492000000004,0.018396399,0.045216430999999994,-0.069258368,-0.030213991000000003,0.036364068,-0.005862829,-0.049951298,-0.109780622,-0.01518779,1.280598282,2.180638079,-0.036553122,0.55564579,-0.10534706099999999,0.059454047999999995,0.037506355,-0.730024742,-1.988781049,0.8005091129999999,-1455.5622311127372 -3467,3467,I206N,-0.07639246,-0.097453212,-0.084877025,-0.115021107,-0.545276258,-0.032856908,-0.10187433,-0.05091059,0.019878297,-0.097045356,-0.097861067,-0.069200375,-0.10055367400000001,-0.100784376,-0.129257838,-0.583464676,-0.50708784,1.560446251,1.82713522,-4.219549219,-4.542879295,-3.710311043,-2.9704663239999998,-4.730273148,-5.143816284,-3.899577423,-2.183210967,-1468.9577143006027 -3468,3468,I206Q,0.029201497000000003,-0.07881144400000001,-0.042334195,-0.025677079,-0.043686221,0.002203199,0.004296914000000001,0.054106079,0.045781937,0.009039369,-0.16666225699999998,-0.074263676,-0.010404714,-0.041794624,-0.009559534,-0.117864662,0.030492221,1.230533656,2.126666669,-1.5226949369999998,-1.917375771,-1.916713539,-0.837482803,-0.663381546,-2.278521027,-2.170622594,-1.412007112,-1469.4774353597313 -3469,3469,I206P,0.000471761,-0.291522652,-1.779102921,-2.247104658,-2.7935813310000004,0.050500987000000004,0.018342382,-0.017398861,0.022158294,-0.203388455,-0.379656848,-2.085341555,-1.4728642859999999,-2.312040052,-2.182169264,-2.727773562,-2.859389099,0.6419590039999999,-0.22100654399999997,-7.401030563,-6.512406586,-6.871379822000001,-7.617098854,-7.4493211520000004,-8.554946403999999,-7.193116032000001,-6.609444902000001,-1467.221511268057 -3470,3470,I206S,0.014117386,-0.060086527,-0.029719633999999998,-0.032810553,-0.109283774,0.00025958400000000004,0.012277943000000001,0.015956829,0.039923626000000004,-0.013575131,-0.106597922,-0.063212492,0.0037732240000000004,-0.01245919,-0.053161915,-0.154436056,-0.064131492,1.5168272369999998,2.312321322,-3.7838341489999996,-3.734803543,-3.669640533,-3.487393883,-3.6073060989999997,-4.420026688,-3.245276052,-2.93914146,-1466.9182053315453 -3471,3471,I206R,0.025828252000000003,-0.01377985,-0.016197196,-0.038110036,-0.09609221300000001,0.011311628,0.026284887000000003,0.025371617000000003,0.0343773,0.05204758,-0.07960728,-0.068735768,0.036341376,-0.017784993,-0.058435079,-0.140715911,-0.051468515,1.317294567,2.17960245,-1.863715332,-1.2344766390000002,-2.427891823,-1.72367675,-1.0861884990000001,-2.846342949,-1.921414061,0.116348219,-1468.9838529773988 -3472,3472,I206T,0.042614654,-0.022792241,0.0009750410000000001,-0.034564326,-0.092170431,-0.031852644,0.037801507000000005,0.047427801,0.01514372,0.025286599,-0.07087108,-0.020312629,0.022262711,0.001674334,-0.070802985,-0.121416629,-0.062924232,1.319106307,2.243707257,-1.176565407,-1.4465295790000001,-1.51588694,-1.515139503,-0.875823303,-0.529447708,-1.26535325,0.024509321,-1468.8423512484878 -3473,3473,I206W,0.05810368900000001,-0.053842374000000005,-0.043425503,-0.050314221,-0.059908443,-0.002041336,0.07206676599999999,0.044140612,0.024982288,-0.012563717,-0.09512103,-0.135897928,0.049046922,-0.042665477,-0.057962965,-0.137351878,0.017534992,1.394835485,2.216405331,-5.302861824,-3.8248687360000004,-2.4296989669999998,-5.167549477,-6.690173317,-8.402018623,-5.063644327,-1.201339427,-1456.9867942552082 -3474,3474,I206V,0.06953582400000001,0.016368188,0.02299752,-0.024435354,-0.052187525,-0.030983962,0.070100704,0.06897094299999999,0.051695465,0.049900162000000005,-0.017163787,-0.00046566,0.046460699999999994,-0.012251211000000001,-0.036619497,-0.09947531300000001,-0.004899736,1.395511931,2.313337165,-1.3465446330000002,-1.231473282,-1.4253665469999999,-1.65223674,-0.760181358,-1.66346524,-2.454222638,-0.6059509160000001,-1464.9509480590932 -3475,3475,I206Y,0.040908949,0.040893773,-0.079761211,-0.008538211,-0.10040778800000001,-0.109105181,0.046709355999999994,0.035108541,0.09315347800000001,0.13419909800000002,-0.052411552,-0.140506514,-0.019015907,0.031847367,-0.048923789,-0.09142897400000001,-0.109386602,1.3271953429999999,2.2967871140000002,-6.119303307999999,-6.407345352,-3.7153267060000004,-7.455663672999999,-7.152918419,-5.86526239,-5.199908006999999,-1.28047204,-1457.189998259768 -3476,3476,D207A,-0.062229479000000004,-0.045654257000000004,-0.027258616,-0.031301506,-0.024022197000000002,0.038410698,-0.05996719,-0.064491768,0.032718807999999995,-0.020184848000000002,-0.071123665,-0.042907107,-0.011610125,-0.018439979,-0.044163032000000005,0.011925898999999998,-0.059970292,1.178267571,2.593060595,-0.334295882,-0.001144165,-0.608751328,0.093880608,0.011962357,-1.16742688,-2.439769816,-0.7952136390000001,-1459.3584233573638 -3477,3477,D207C,0.010585694,-0.043857762,-0.003090153,0.0056290609999999994,-0.08019127,0.041584525,0.009075379,0.012096009,0.023033137000000002,-0.066821471,-0.020894052,-0.018188746000000002,0.01200844,0.014746,-0.003487878,-0.022340232999999998,-0.138042306,1.184000001,2.533465974,-6.555776992999999,-6.234379272000001,-6.418387077,-7.165271652,-6.430414032000001,-6.53043293,-8.138107932999999,-8.923942928999999,-1457.866185403429 -3478,3478,D207E,-0.04176011,-0.051951305999999996,-0.019379709,-0.033905602,0.004128037,0.027629155,-0.028227375,-0.055292844,0.021005601000000002,-0.019637633999999998,-0.08426497699999999,-0.025794797999999997,-0.012964618999999998,-0.012942098999999999,-0.054869104,0.040631972999999995,-0.0323759,1.128027136,2.776403782,-0.662769107,-0.599143021,-0.88213916,-0.896062767,-0.400706825,-0.5357937620000001,-1.601503474,-0.692290117,-1458.6162357614376 -3479,3479,D207G,-0.038288475,-0.035304962,-0.016086804,-0.027988322000000003,-0.016034947,0.046896712,-0.027638932,-0.048938017,0.00180474,-0.02555868,-0.045051244000000004,-0.004173631,-0.027999977000000002,-0.0017368239999999999,-0.054239819,0.023876772,-0.055946666,1.0604782529999999,2.646715663,-1.376860916,-1.52169265,-1.366205795,-0.47899511,-1.038818863,-2.478592163,-2.905158732,-0.645666795,-1463.1879550479352 -3480,3480,D207F,-0.040534289,-0.044215323,-0.048585087,-0.027121364,-0.184123466,0.056235372,-0.004906908,-0.07616167,-0.004511654,-0.041842409,-0.046588237000000005,-0.0510629,-0.046107273,-0.019985381,-0.034257347,-0.148947954,-0.219298977,1.460766913,2.276557478,-6.505832027,-6.155939888,-5.583940941,-7.981839012000001,-6.631290581,-6.176149712000001,-6.7810197489999995,-6.29822789,-1454.127482515294 -3481,3481,D207I,-0.046580737000000004,-0.011509082,0.018161902,-0.024129632,-0.183733321,0.020730646000000002,-0.028920302000000002,-0.064241172,-0.006542496,0.043429902,-0.066448065,0.016490212,0.019833592,-0.0044382679999999996,-0.043820995,-0.086046632,-0.28142000899999997,1.389820332,2.381473061,-4.437585503999999,-4.283929038999999,-4.3803289030000006,-4.637267754,-3.772836502,-5.113565323,-5.193057651,-4.7284600039999996,-1452.4077517623082 -3482,3482,D207H,-0.041334043,-0.020158066999999998,-0.025731558999999998,-0.019124019,-0.02671686,0.05108352,-0.016771435,-0.06589665,0.020025283999999997,-0.00252764,-0.037788493,-0.05388908,0.0024259629999999997,0.018489231999999998,-0.05673726900000001,-0.00844768,-0.044986039000000005,1.225252326,2.372969189,-2.0202365909999997,-1.64715464,-2.049554558,-2.3971904680000002,-1.886979317,-2.12030397,-3.156065845,-2.693722337,-1453.8610473205335 -3483,3483,D207K,-0.06931475,-0.071966898,-0.033428677999999996,-0.041045916,-0.068487126,0.020119835,-0.048861057,-0.08976844199999999,0.010045264,-0.062542673,-0.081391122,-0.005703034,-0.061154322000000004,-0.004883892,-0.077207939,0.0067783140000000006,-0.143752565,1.160606965,2.538294051,-1.9920116419999998,-1.977584084,-2.241929016,-2.9747031560000003,-1.8723608930000002,-0.893481064,-3.5118291160000004,-1.3013868370000001,-1449.3950606063008 -3484,3484,D207M,-0.028001011,-0.021628026,-0.006265159,-0.00327726,-0.025048737,0.017259441,-0.008326609,-0.047675413,0.048785483,0.008112023000000001,-0.051368075,-0.030716035,0.018185717,-0.025834175,0.019279656000000003,0.038750783999999996,-0.08884825800000001,1.207092001,2.7661460110000005,-4.588306856,-4.641037575,-4.223224129,-4.66292543,-4.428940506,-4.985406639,-5.386453962999999,-4.74635679,-1451.4756181095727 -3485,3485,D207L,-0.040484176000000004,-0.020028957,-0.0047328990000000005,-0.020144275,-0.064457659,0.037958257,-0.019282428,-0.061685924,-0.020499898,0.000762485,-0.040820398,-0.00531378,-0.004152017,-0.011351501000000002,-0.028937049,-0.031204429,-0.09771088900000001,1.2696555040000002,2.4615261459999997,-3.978099484,-4.030092598,-3.781398926,-4.376586693,-3.561358795,-4.14106041,-4.934837261,-4.268073053,-1448.0016349013895 -3486,3486,D207N,0.005602492,-0.011764415,-0.008308064,-0.011479003,-0.010855562,0.07311743799999999,0.027601268999999998,-0.016396286,-0.047756732,-0.041906274,0.018377445,0.0013244079999999998,-0.017940536,0.031479565,-0.054437571,0.000168492,-0.021879615,1.130150153,2.550558713,-1.372388542,-1.050453354,-1.201484451,-2.44535659,-1.146509148,-1.018139168,-4.08296771,-1.6750492369999999,-1459.8225555908866 -3487,3487,D207Q,-0.06438732900000001,-0.11555858699999999,-0.051406943,-0.091283528,-0.072254373,0.026744773,-0.057842165999999993,-0.070932492,0.016903379,-0.15554682,-0.07557035299999999,-0.07914947,-0.023664416,-0.113222782,-0.069344274,-0.074834216,-0.069674529,1.4630610640000001,2.441422517,-0.143463402,0.37666898299999996,-0.052730705,-0.14631998400000001,0.218932335,-1.1138676379999999,-2.157923103,-1.2957538370000001,-1456.4163019838743 -3488,3488,D207P,-0.077697109,-0.033856525,-0.6797158209999999,-1.926697154,-2.74751331,0.15184383699999998,-0.044482223,-0.110911994,-0.034113887999999995,-0.001209598,-0.066503452,-0.642376265,-0.7170553759999999,-1.87347037,-1.9799239380000002,-2.6606295330000003,-2.8343970869999997,2.019837199,0.915196731,-5.45259476,-5.561102211000001,-5.4828789979999994,-5.603601982000001,-5.2240783539999995,-5.391312256,-6.506493701,-5.374169984,-1458.8044270630926 -3489,3489,D207S,-0.011899561000000001,-0.032074722,0.002292015,-0.009120006,0.010865086999999999,0.050958044,-0.001740461,-0.02205866,0.031620201,-0.024541536,-0.039607907000000005,-0.004605499,0.009189529,0.008895522,-0.027135532999999996,0.042116281,-0.020386108,1.040179426,2.597550479,-1.1988190029999999,-0.63722921,-1.348418884,-1.581391525,-1.434955856,-0.992099541,-2.852653432,-1.361043428,-1459.5800559408963 -3490,3490,D207R,-0.045857322,-0.035519088,-0.011863027,-0.017930281,-0.013780093,0.07738064,-0.041279604,-0.05043504,0.014072422,-0.007902791999999999,-0.063135383,-0.015453965,-0.008272088,-0.003612958,-0.032247604,0.013756488999999998,-0.041316675,1.124077095,2.466195628,-0.9784873340000001,-0.5761250920000001,-1.04181707,-1.114392593,-1.177271584,-0.98283033,-1.7796595530000001,-0.893781565,-1447.5123006813228 -3491,3491,D207T,-0.07047065400000001,-0.054292584000000005,-0.049724263,-0.030861444,-0.051384057000000004,0.038294737999999995,-0.066665173,-0.07427613400000001,0.0010276439999999999,-0.051911654,-0.056673512999999995,-0.05152922,-0.047919305999999995,-0.02108244,-0.040640447,-0.016912026,-0.085856087,1.235117378,2.449877744,-1.01109523,-1.038826355,-1.191497635,-0.569880882,-0.41311176299999997,-1.842159515,-2.0788784419999997,-1.3758488080000002,-1458.5341710546054 -3492,3492,D207W,-0.06514415,-0.030409455,0.0027828840000000002,-0.007488766,-0.10318134699999999,0.123116941,-0.04721279900000001,-0.0830755,0.001140185,0.027637765,-0.088456675,0.006530866999999999,-0.000965099,0.049810767,-0.06478829900000001,-0.040590798,-0.165771896,1.374225786,2.5683050030000003,-6.25035424,-5.852524047999999,-5.869268798999999,-6.78347905,-6.544884017999999,-6.201615287999999,-7.035980301,-6.0495325079999995,-1453.0610294118524 -3493,3493,D207V,-0.085287179,-0.054408889,-0.031817229,-0.042565252000000005,-0.15558870000000002,0.082194495,-0.04350517,-0.127069187,-0.005456108,-0.018672947,-0.09014483,-0.025355229,-0.038279229,-0.013008073,-0.072122431,-0.08039769599999999,-0.230779703,1.354216729,2.413301012,-3.9033064960000003,-3.8364645310000003,-4.161396851,-3.790867516,-3.457358047,-4.270445533999999,-5.067221093,-3.8438382719999997,-1453.7712009171955 -3494,3494,D207Y,-0.043655291,-0.038464557999999996,-0.050618475,-0.022883952000000003,-0.089946259,0.04955973,-0.042207005,-0.045103576,-0.022475999,-0.004931327,-0.071997788,-0.035946775,-0.065290175,-0.0054962909999999995,-0.040271612000000005,-0.063422925,-0.11646959300000001,1.320972621,2.407009106,-5.04699563,-4.578328491000001,-4.868100067,-6.429979172,-5.04487532,-4.313695098999999,-5.522636609,-4.374461222,-1452.338160587009 -3495,3495,W208A,-0.06362903,0.13914769,0.025023449,-1.467070906,-1.916460922,0.0029734790000000002,-0.027025875,-0.100232185,0.001911014,0.046197388,0.232097992,0.043929489,0.006117408,-1.286832171,-1.6473096409999999,-2.211637873,-1.62128397,0.554059477,0.709617885,-11.14622098,-9.735963073999999,-11.666325,-11.71518243,-10.94425308,-11.66938132,-6.481078749,-2.614055917,-1439.195047758054 -3496,3496,W208C,-0.05714613,0.121219803,-0.029726779,-1.5531601169999998,-2.212615247,0.038373563,-0.011717733000000001,-0.102574526,-0.04853718,-0.0019296510000000001,0.244369257,-0.030530863,-0.028922695,-1.4395623430000002,-1.66675789,-2.389191629,-2.036038864,0.8333378379999999,0.720586869,-12.90465062,-12.87979081,-13.23821391,-13.10976931,-12.76844306,-12.52703603,-8.299972988,-4.964786465,-1454.9008161379024 -3497,3497,W208E,-0.062775886,0.09170605400000001,0.006469814,-1.551703331,-2.293189931,-0.002036211,-0.030193206,-0.09535856599999999,0.09710964300000001,-0.027189336,0.210601443,0.009385209,0.003554419,-1.66232332,-1.441083342,-2.1969792580000003,-2.389400604,0.8219953999999999,0.6935463040000001,-13.69049042,-12.98545329,-14.70380125,-13.72492908,-13.78242682,-13.25584165,-9.371033667,-6.297051989,-1448.9061684273183 -3498,3498,W208D,-0.051759837999999996,0.066382951,-0.003051528,-0.26760631,-1.7929408080000002,-0.000971192,-0.012447514,-0.091072162,-0.083232493,-0.037924276,0.170690178,-0.025428053,0.019324998,-0.097157113,-0.43805550600000004,-1.89574486,-1.690136755,0.877627705,1.30889981,-12.22653123,-11.05288818,-12.83011995,-12.06188233,-13.23565437,-11.95211134,-7.643585477,-4.2296488519999995,-1447.6562994783744 -3499,3499,W208G,-0.063815187,-0.060850883,-1.422979542,-2.0960791469999998,-2.512143778,0.012052073,-0.028916697,-0.09871367699999999,-0.055898817999999996,-0.049935004000000005,-0.071766762,-1.4240738880000001,-1.421885195,-2.0671885740000002,-2.124969719,-2.511667881,-2.512619675,0.807271849,0.059876585999999996,-11.549307,-11.03348699,-12.08071264,-10.49850535,-11.93664297,-12.19718703,-7.471623646,-5.313393607,-1445.8981005279347 -3500,3500,W208F,-0.011549843999999998,0.102015059,0.038283691,0.036925221,-0.969442853,-0.020340716000000002,0.028571791000000003,-0.051671479000000006,0.114422618,0.021433433999999998,0.182596683,-0.00268094,0.079248321,-0.030163926,0.104014367,-1.03912241,-0.899763295,0.817433272,1.3680282990000001,-10.20756454,-9.828221663999999,-8.720377441,-10.94900566,-8.882167419,-12.65805051,-7.600700524,-2.814565613,-1449.843695529271 -3501,3501,W208I,-0.082512398,0.119666521,-0.082327535,-1.653077336,-2.5446781990000003,-0.009955122,-0.035991284,-0.129033512,-0.069221779,0.037135375,0.20219766600000003,-0.081402577,-0.083252493,-1.4545215009999999,-1.85163317,-2.330364573,-2.7589918239999998,0.804919196,0.715346478,-10.30938004,-11.89781244,-10.16971111,-12.90300116,-9.402437592,-7.173937912,-7.438310078,-0.550210024,-1439.739209308289 -3502,3502,W208H,-0.036072135,0.12502655199999999,0.018422025,-1.591976934,-2.123041474,0.03256793,0.014804086000000001,-0.086948355,0.14679742699999998,-0.011507168,0.261560271,0.015476496000000001,0.021367554,-1.4430874790000001,-1.7408663880000002,-2.292601613,-1.953481335,0.804984148,0.717418144,-11.1604726,-10.58365697,-13.30779218,-10.09392615,-10.84641489,-10.97057284,-7.683621163,-3.684233724,-1450.5757385971956 -3503,3503,W208K,-0.07054185,-0.592445081,-1.7830253059999999,-2.134174362,-2.266433854,0.072954884,-0.038273935,-0.102809765,-0.050996959,-0.6356290689999999,-0.5492610920000001,-1.757851344,-1.8081992669999998,-2.020754787,-2.247593936,-2.794292814,-1.738574894,3.056372756,1.188732294,-13.72657658,-13.06398225,-15.94034407,-13.60854117,-13.5441643,-12.47585112,-9.82486594,-6.560161099999999,-1447.3856491805054 -3504,3504,W208M,-0.015287271000000002,0.14924828199999998,0.016696593,0.067860262,-0.953390179,0.030505741,0.026027923999999997,-0.056602465,-0.090411078,0.027860672000000003,0.270635891,0.003099545,0.03029364,0.012474954,0.12324557,-0.831937235,-1.074843123,0.8066982890000001,1.3966525580000002,-9.763819188,-10.08924507,-9.51038797,-11.33913677,-8.955105057,-8.925221069,-6.235516854,-2.450617323,-1446.177522370126 -3505,3505,W208L,-0.052013305,0.149693474,0.037001321000000004,0.07191095900000001,-1.4011797819999998,0.039930587999999996,-0.012083788,-0.091942821,-0.038101977999999995,0.040904146,0.25848280100000004,0.044734685999999996,0.029267955,0.059302137000000005,0.08451978,-1.6274901480000001,-1.174869416,0.59231512,1.310115683,-8.678854317999999,-9.243062851,-8.246988525,-10.67182776,-6.881146164,-8.351246292,-5.768200319,-1.128836958,-1433.4415867673233 -3506,3506,W208N,-0.049050576,0.186140764,-0.041764751,-1.6134128319999999,-2.4963600390000003,0.044879293,-0.036276155,-0.06182499599999999,-0.023464288,0.076627632,0.295653895,-0.011726737,-0.071802764,-1.492869815,-1.7339558480000001,-2.5246858569999997,-2.468034221,0.74995331,0.70905245,-12.42419212,-12.44121762,-13.13643768,-11.95745391,-12.86048991,-11.72536151,-8.149273276,-3.58038137,-1447.9169922964647 -3507,3507,W208Q,-0.07514014,0.110468458,-0.221968208,-1.689327135,-2.720273122,0.030998695,-0.039981666,-0.110298614,-0.030876787000000003,-0.020839491,0.241776407,-0.108063336,-0.33587308,-1.656697149,-1.721957121,-2.641088541,-2.7994577019999998,0.929496817,0.70740533,-11.71181391,-12.04912492,-13.20082405,-11.92709264,-11.42127155,-9.960756355,-8.352695506,-5.3316344430000004,-1448.7613141969778 -3508,3508,W208P,-0.070865373,-1.016465859,-1.906857375,-2.178265016,-3.079917716,0.03426964,-0.040284479,-0.101446266,0.005411839,-1.084570088,-0.9483616290000001,-1.80789324,-2.005821509,-2.154899166,-2.201630866,-2.889413085,-3.270422347,3.1714550389999996,1.075573397,-14.66319947,-13.65804826,-15.47036027,-15.33712205,-13.97173758,-14.87872918,-8.816572792999999,-5.0819716580000005,-1453.2458708886988 -3509,3509,W208S,-0.031524286,0.13736700000000002,-0.19024527300000002,-1.6894518219999999,-2.1544361309999998,0.018330803,0.011818549,-0.07486712,-0.17034827600000002,0.003980365,0.27075363399999997,-0.134922921,-0.24556762399999998,-1.618133108,-1.7607705359999999,-2.307026994,-2.0018452680000003,1.053129377,0.722979365,-11.89392921,-11.40514136,-11.87418256,-11.64802093,-12.12481061,-12.41749059,-7.672475359,-4.253343731,-1446.7248478615656 -3510,3510,W208R,-0.051789285,-0.286493544,-1.525321092,-2.106920362,-2.8279599689999997,0.047430124000000004,-0.020079081000000002,-0.083499488,0.0008520410000000001,-0.254543917,-0.31844317,-1.5257567269999999,-1.524885456,-2.071778577,-2.142062146,-2.636831816,-3.019088122,2.681788097,1.03146795,-10.84669366,-11.72806085,-12.06998188,-10.35545567,-11.65653661,-8.423433272999999,-8.078607466000001,-5.329241247,-1444.1204325091094 -3511,3511,W208T,-0.069405571,0.12638569,-0.18792833399999997,-1.676308318,-2.4204022419999998,0.038934267,-0.025191513999999998,-0.11361962699999999,-0.046444564,0.02742236,0.22534901899999998,-0.11466403300000001,-0.261192634,-1.727916859,-1.6246997769999998,-2.578936347,-2.261868137,0.9406729429999999,0.700051781,-9.868649854,-10.50319552,-10.52746169,-10.08416125,-7.886942795,-10.34148801,-6.895188955,-2.051046061,-1443.0363167505711 -3512,3512,W208V,-0.05682759999999999,0.135182222,-0.802637307,-1.800203315,-2.66192783,0.031385009,-0.021477205,-0.092177994,-0.176431749,0.046044297000000005,0.22432014600000003,-0.516499059,-1.0887755540000001,-1.6321148019999998,-1.9682918269999998,-2.824782136,-2.499073524,1.8303746769999998,0.905720545,-11.08542168,-12.06979723,-11.31650025,-12.11756081,-10.29271818,-9.630531952,-5.40677861,-1.793880427,-1443.167741470039 -3513,3513,W208Y,-0.07557349299999999,0.128724001,0.028299705,0.045436385,-1.4290652869999998,-0.021150189,-0.047613332,-0.103533654,-0.127213726,-0.000419124,0.257867125,0.010178378,0.046421032,0.021793292000000002,0.069079478,-1.632434084,-1.22569649,0.547558699,1.3076368090000001,-10.00539543,-10.22075278,-9.609655212,-9.615537514,-9.49898674,-11.08204491,-7.831612207,-3.398521745,-1446.961765669752 -3514,3514,M209A,0.011769685,0.18411577899999998,0.017205486000000002,-1.6199433269999999,-2.03056525,0.035001732,0.020360289,0.003179081,-0.034959897000000004,0.012606257,0.3556253,-0.03689849,0.07130946099999999,-1.264843886,-1.975042767,-2.370179306,-1.690951193,0.947747434,0.750002065,-8.234347057999999,-7.832445961,-8.035463829,-7.929872177000001,-8.600264083999999,-8.77368924,-8.416307439,-6.307476726,-1456.845441413112 -3515,3515,M209C,0.05786613,0.229378553,0.02504521,0.098222533,-1.1524602990000001,-0.072790773,0.071621385,0.044110874,-0.006721416,0.039998431,0.418758674,0.032430105,0.017660315,-0.000171948,0.196617013,-1.634852156,-0.6700684410000001,0.61234398,1.310415243,-10.98406441,-10.75067282,-10.42047305,-10.41566914,-11.08248943,-12.25101762,-10.48843537,-10.30909939,-1457.0284063811414 -3516,3516,M209E,-0.032227282,-0.8813101959999999,-2.304691151,-2.319253869,-2.9213960589999997,0.014029284,-0.021535283,-0.042919281,0.030023598,-0.9074268040000001,-0.855193588,-2.7089251360000004,-1.900457166,-2.195325016,-2.443182722,-2.543698485,-3.299093632,0.33925344799999996,-0.620805285,-11.28385336,-10.61390013,-10.94904324,-10.61903944,-11.64503513,-12.59224886,-10.48843537,-10.30909939,-1470.5019849506207 -3517,3517,M209D,-0.017045493999999998,-1.564393614,-2.095602608,-2.701630668,-3.002742861,0.012050571999999999,-0.02065937,-0.013431618000000001,-0.089672907,-1.855709602,-1.273077625,-2.172908096,-2.01829712,-2.261367966,-3.141893369,-2.910771431,-3.0947142910000003,-0.597917121,-1.123790675,-11.68870713,-10.959922500000001,-11.60323131,-10.86522088,-12.01450696,-13.00065399,-10.48150989,-10.27089108,-1468.5930139119737 -3518,3518,M209G,-0.016201071,0.155156447,-0.14004566400000001,-1.732685089,-2.678930153,0.006776038000000001,0.008220426,-0.040622568,-0.017959241,0.01724087,0.293072023,-0.14290977900000001,-0.137181549,-1.6795113609999999,-1.785858816,-2.596776458,-2.761083847,1.018145967,0.712201933,-10.03010107,-8.954619911,-9.728741966,-9.517863945,-9.818865494,-12.13041405,-8.930507795,-6.952508032000001,-1464.4342352272943 -3519,3519,M209F,-0.029783629,0.134616246,-0.14352879300000002,-1.615656226,-2.914586017,-0.015163508999999999,-0.023790582999999997,-0.035776674,0.006690135,0.006832328,0.262400163,-0.151718797,-0.13533878900000001,-1.4612370719999999,-1.77007538,-2.8510032260000004,-2.978168807,1.109838957,0.752625051,-7.451167948999999,-8.403774283999999,-5.547861191,-6.762965027000001,-7.845784042000001,-8.6954552,-7.347199345,-4.154184197,-1452.8926251418889 -3520,3520,M209I,-0.053541278,0.127687975,-0.949520824,-1.857301499,-2.834504952,-0.068630775,-0.026762342999999997,-0.080320212,-0.004646334,0.063909442,0.19146650699999998,-0.711026808,-1.188014839,-1.723765964,-1.9908370340000001,-2.7711094380000003,-2.8979004660000003,2.041826766,0.9602672609999999,-6.198722543,-5.259169098,-5.741379936,-6.397368599,-7.178577965,-6.417117118999999,-7.3205966170000005,-4.760548719,-1451.9438327648677 -3521,3521,M209H,-0.01826486,-1.286444407,-2.307058752,-2.185120833,-2.8753086519999997,0.05919400599999999,0.0230848,-0.05961452,0.007555643000000001,-1.317929282,-1.254959531,-2.237187767,-2.376929736,-2.325647637,-2.044594029,-3.1511423610000002,-2.599474942,0.053345004,-0.8076681929999999,-11.27219172,-11.05976984,-10.13057114,-10.97843627,-11.24425077,-12.94793058,-9.75981237,-7.503679155,-1461.9920168337412 -3522,3522,M209K,-0.059917095,-1.066810284,-2.055304181,-2.24937787,-2.9395656889999997,0.02731059,-0.03285155,-0.08698264,-0.029315557000000003,-0.97892152,-1.154699048,-1.949332527,-2.161275834,-1.912853661,-2.5859020790000002,-2.8632871210000004,-3.0158442560000003,3.491773005,1.412317995,-10.59383957,-10.00724699,-10.39223649,-9.654688599,-10.73265281,-12.18237295,-9.858186806,-7.503679155,-1468.869766027201 -3523,3523,M209L,0.18369905600000003,0.14036505,0.059101975999999994,0.069382862,-0.620492384,-0.049808530999999996,0.06463159,0.302766522,-0.032767502000000004,0.051759862000000004,0.228970237,0.008626495999999999,0.109577455,-0.039284526,0.17805025,-0.73311796,-0.507866807,0.8444287159999999,1.424685583,-3.254801871,-5.433984184,-2.252779243,-2.393698692,-3.59259185,-2.600955383,-4.795122265,0.00491984,-1459.5327452039346 -3524,3524,M209N,0.039360648,-1.031817908,-2.374158591,-2.3921410219999997,-2.781298845,0.06342757,0.058570541,0.020150754,0.04768915,-1.064170155,-0.9994656609999999,-1.983428639,-2.764888543,-2.372918506,-2.4113635369999997,-2.721291975,-2.8413057139999998,0.265210349,-0.665009145,-10.38831378,-9.438246902000001,-10.20355776,-9.379296417,-11.1266406,-11.79382724,-9.301837557999999,-7.062170028,-1463.5625996608287 -3525,3525,M209Q,0.353013124,-0.6553106360000001,-0.473593183,-2.121439728,-2.48502129,-0.0014936539999999999,0.050969865,0.655056382,-0.030937244,0.01274323,-1.323364501,-0.32303754100000004,-0.6241488239999999,-2.07188851,-2.170990946,-2.545200716,-2.4248418640000002,1.312499577,0.6705365870000001,-11.31080268,-10.76001436,-10.99082561,-10.67722396,-11.43665037,-12.68929912,-10.48843537,-10.30909939,-1465.8688364131376 -3526,3526,M209P,0.000614608,-1.427255247,-2.018035649,-2.450415844,-2.830617872,0.0278144,0.032162208,-0.030932992000000003,-0.096449837,-1.6852222209999999,-1.169288272,-2.073776623,-1.962294675,-2.308364529,-2.5924671580000003,-2.878586748,-2.7826489960000003,-0.060761132999999995,-1.067142865,-11.35745531,-10.74641993,-11.15130801,-10.73334699,-11.68765267,-12.46854893,-10.48843537,-10.30909939,-1474.8741456605494 -3527,3527,M209S,-0.015921345,0.12963538,-1.4175789980000002,-2.274155201,-2.819777634,0.034742444,0.024844751,-0.056687441,-0.018675398,-0.015144949,0.274415709,-1.347648516,-1.48750948,-2.496806226,-2.051504176,-2.970118432,-2.669436836,0.65588571,0.059889592,-10.85075517,-9.864848755,-10.51553117,-10.365034199999998,-11.12579,-12.38257173,-10.48843537,-10.30909939,-1464.640182393603 -3528,3528,M209R,-0.058272715,-1.390937499,-2.04965505,-2.350668649,-3.260522815,0.02393047,-0.035502469,-0.081042961,-0.11840326300000001,-1.671142238,-1.11073276,-1.9635171480000002,-2.135792952,-2.5290982730000002,-2.172239025,-3.3545929969999997,-3.166452633,-0.229121918,-1.083860858,-11.85905716,-11.16214573,-11.54105358,-11.09559925,-11.95864187,-13.53784536,-10.46529589,-10.13596353,-1462.4317944343202 -3529,3529,M209T,-0.007710137,0.17680558300000002,-0.718018598,-2.2440100309999997,-3.405201876,-0.025451562999999996,-0.005623505,-0.009796768,0.009907965,0.000457575,0.353153591,-0.46229411,-0.9737430859999999,-2.283147741,-2.20487232,-3.330491214,-3.4799125369999997,1.351422269,0.575689633,-7.227355137999999,-6.77149353,-6.863253716,-7.110683807000001,-7.655381821000001,-7.735962814,-7.88333753,-5.281195189,-1461.0208944994956 -3530,3530,M209W,0.006535758000000001,0.154341123,-0.29280223699999997,-1.8639626930000002,-2.349063279,-0.061086979000000007,0.007188893000000001,0.005882622,-0.01087495,0.05593606,0.25274618600000004,-0.254722626,-0.330881847,-1.732939056,-1.99498633,-2.479252534,-2.2188740240000002,1.2582808840000002,0.732993908,-11.51891489,-11.68998074,-10.77149966,-10.29609209,-11.69972744,-13.13727451,-10.48843537,-10.30909939,-1444.5063043450937 -3531,3531,M209V,0.024066897,-0.026424352999999998,-1.53298494,-2.294382739,-2.529281553,-0.037321787,0.045162247,0.002971547,-0.018298257,-0.092757287,0.039908582000000005,-1.65002935,-1.41594053,-2.361738511,-2.227026966,-2.630930734,-2.4276323719999997,0.7921123940000001,0.01177928,-7.980053839,-7.457436241,-7.307254127999999,-7.7540306779999995,-8.78968718,-8.59186097,-8.500501821,-6.359663502,-1455.9312301306054 -3532,3532,M209Y,-0.11401198,-0.9518259109999999,-1.9782430969999998,-2.53581615,-2.924973973,0.027968773,-0.112954076,-0.115069884,0.062714725,-1.120606756,-0.7830450659999999,-1.765164184,-2.19132201,-2.455684045,-2.615948254,-2.804057515,-3.045890431,2.43024275,0.40316500299999997,-10.41650902,-10.31264651,-8.941965523,-9.479626305,-10.47513232,-12.87317445,-9.349987951000001,-6.7479335339999995,-1439.6442953790538 -3533,3533,E210A,0.405231086,0.388018931,-0.050120514000000005,-0.054879976,-0.372386731,-0.079054029,0.016454322,0.79400785,0.056278537999999996,0.062930556,0.7131073059999999,0.01695591,-0.11719693800000001,0.065281245,-0.175041196,-0.145860111,-0.598913351,1.2393932490000001,2.108541614,-2.669873622,-1.880144669,-2.841089638,-2.159469109,-3.9882665630000003,-2.480398132,-3.302840476,0.07835725,-1457.3466824758798 -3534,3534,E210C,0.043418980999999995,-0.09085302199999999,0.011745722,0.027111991000000002,0.150784067,-0.042845637,0.100126761,-0.0132888,-0.042618706,0.001259993,-0.182966037,-0.03288403,0.056375472999999995,-0.032383407,0.086607389,-0.10738070400000001,0.408948838,1.102568107,2.054550149,-6.143429877999999,-5.881696503,-5.688019089,-5.653897338999999,-7.0942953189999995,-6.399241142,-5.429605626,-2.3626352219999998,-1455.9815920367837 -3535,3535,E210D,-0.010470772,-0.006385618000000001,0.052059100999999997,0.056391822,-0.15808265400000002,-0.058545060999999995,0.029365681,-0.050307224000000005,0.070972484,0.096494939,-0.109266175,0.037748905,0.066369296,0.073681228,0.039102415,-0.339537219,0.023371912,0.8396874520000001,1.57317866,-4.150981783,-3.708028183,-2.9633185419999997,-3.554049492,-5.190730911,-5.338781784,-5.609011627999999,-2.131235656,-1462.5046759210527 -3536,3536,E210G,0.117846663,0.12614804599999999,-0.008503527,0.021204341,-0.326654622,-0.068688007,0.020512616,0.215180709,0.022742514,0.05511795,0.197178141,0.00850118,-0.025508232999999998,0.023253772000000002,0.019154908999999998,-0.5237207110000001,-0.129588533,0.60147228,1.411338368,-5.603778752,-2.739109024,-5.123212776,-6.124613571,-6.702940895,-7.3290174939999995,-5.367433951000001,-0.08863587099999999,-1461.9584161033854 -3537,3537,E210F,-0.049800446,-0.029488683999999998,0.027137356,0.001953757,0.145238067,-0.006087363,-0.005208486,-0.094392406,0.037558342,0.056947309,-0.11592467599999999,0.064445561,-0.01017085,0.015225845,-0.011318331000000001,-0.098144602,0.388620736,1.422248138,2.445432577,-5.9000536939999995,-5.520920746,-4.974382675,-6.004401756,-7.318266014,-5.682297279,-5.045289746,-2.2861467909999997,-1453.7304789694026 -3538,3538,E210I,-0.023842878999999997,-0.072426141,0.038094362,0.069639526,0.34857084299999996,-0.021439062999999998,0.020258062,-0.06794382,-0.009407697,0.112917263,-0.257769545,0.070001847,0.0061868769999999995,0.09172509699999999,0.047553954,0.079605569,0.617536116,1.0787479640000002,3.00070599,-0.512143542,-0.409992271,-0.834536385,-0.620519615,-0.852122719,0.156453278,-2.233015221,-0.13517069199999998,-1455.4642439214513 -3539,3539,E210H,0.0044056370000000004,-0.012123861000000001,-0.015931688,0.03566448,0.153639001,-0.068999807,0.038263674,-0.0294524,0.0056398559999999995,0.089031883,-0.113279604,-0.024095777000000002,-0.0077675980000000006,0.046433382999999995,0.024895577000000002,-0.143831665,0.45110966700000005,1.310114585,2.176296874,-5.176834471,-4.262331085,-4.638233284,-6.269197067,-5.714887589,-4.999523331000001,-5.778200837999999,-2.151249966,-1457.928119014483 -3540,3540,E210K,-0.009865764,-0.070920553,0.011305285,0.03523272,0.232897995,-0.060023106,0.041690078,-0.061421606,0.005435774,0.035212819,-0.17705392399999997,0.0026588809999999997,0.019951688999999998,0.017541138,0.05292430099999999,-0.133046054,0.598842043,1.1839557170000001,2.102080861,-1.779657755,-1.452371071,-1.83388015,-2.5065397259999997,-2.045710793,-1.0597870329999999,-3.811103037,0.7587523209999999,-1460.8080283422023 -3541,3541,E210M,-0.028603721000000002,-0.057613261,0.021951169,0.031421455,0.19417498600000002,-0.044399882,0.011077188,-0.06828463,0.009015722,0.055138781,-0.170365303,0.040091269,0.0038110690000000003,0.039579061,0.023263849,-0.053265277,0.44161524799999996,1.171423235,2.36905779,-3.2618946039999996,-3.1042939069999997,-3.50914991,-3.506219002,-4.114300858,-2.075509346,-4.081908536,-1.774940411,-1453.2806651326828 -3542,3542,E210L,0.002445311,-0.00900026,0.0052436869999999995,0.011845808000000001,-0.15600398699999998,-0.027440425,-0.010908936000000001,0.015799557,0.022582748,0.06093588,-0.07893639999999999,0.006664231999999999,0.0038231420000000003,0.021113596000000002,0.002578019,-0.22660799199999998,-0.085399981,1.4026958969999999,2.0932990019999997,-2.346255745,-2.551316429,-2.470706978,-2.227656799,-3.613330505,-0.868268013,-2.940988705,0.416533108,-1453.156335348729 -3543,3543,E210N,0.022183999,0.0026827659999999996,0.00019822200000000001,0.055981697999999996,0.082515748,-0.055851987,0.08669166800000001,-0.04232367099999999,0.00129131,0.08254258099999999,-0.07717705,0.01791876,-0.017522317,0.020693168,0.091270227,-0.245414188,0.41044568299999995,1.057480628,1.791401693,-5.130836455,-4.147608322,-5.178827713,-5.0176017989999995,-5.815974838,-5.494169601,-5.103757109,-1.986481164,-1460.5549046886154 -3544,3544,E210Q,0.029467628,0.042838032000000005,-0.010458627,0.079244332,0.054612238,-0.00604481,0.029088588999999998,0.029846667,0.015534909,0.104379383,-0.018703319,0.029768204,-0.050685457,0.086615817,0.07187284599999999,-0.000321649,0.109546125,1.049841855,2.635588792,-1.165588857,-1.1449366909999998,-1.093659943,-1.539025154,-1.110156448,-0.940166046,-2.556013994,-0.7210337,-1464.1925097056665 -3545,3545,E210P,0.25023387399999997,-0.7178393,-1.8889981059999998,-1.86261881,-1.7423347319999998,0.021406087,-0.045602150999999994,0.5460698979999999,0.098033396,-1.070539519,-0.36513908,-2.471627817,-1.3063683940000002,-2.173774421,-1.5514631980000002,-2.618761029,-0.8659084340000001,0.37096098,-0.668988192,-8.630677802000001,-7.71627108,-8.256324524,-8.49186174,-10.31446027,-8.37447139,-7.979180603,-5.505594114,-1457.0991279431619 -3546,3546,E210S,0.025652072999999997,-0.027052057999999997,-0.003643922,0.027287047999999998,-0.42321718700000005,-0.09234781199999999,0.058452923,-0.007148778000000001,0.012297853999999999,0.038846802,-0.092950917,-0.003645981,-0.003641863,0.038008967000000005,0.016565128000000002,-0.57125288,-0.27518149399999997,0.554150851,1.3905700769999998,-4.35257854,-3.62846814,-3.292987877,-3.5753743589999996,-6.025782181,-5.240280144,-3.7459855839999996,0.106292344,-1458.5001271818765 -3547,3547,E210R,0.068183602,0.013112317,-0.00369791,0.016560909,0.07051385,-0.041405924,0.044509415,0.09185778800000001,0.057476125,0.042053535999999996,-0.015828903000000002,0.003214266,-0.010610085,0.02296335,0.010158468,-0.144723792,0.285751492,1.4134248459999998,2.246096252,-2.5651362559999997,-2.204315186,-2.234721687,-2.8774660489999997,-3.500263908,-2.008914452,-3.150688365,0.674518058,-1459.646576113999 -3548,3548,E210T,0.04238607900000001,-0.00265192,-0.046493902000000004,0.016081757,-0.342551855,-0.06225205599999999,0.050355392,0.034416765,0.028799909,0.054291674000000005,-0.059595514,-0.026601157,-0.06638664700000001,-0.005856914,0.038020427,-0.290734877,-0.394368833,0.833966965,1.606469575,-2.8684812269999997,-2.137548599,-2.085857933,-2.598519135,-4.066275429,-3.45420504,-3.704598044,-0.106336189,-1456.2873047329485 -3549,3549,E210W,0.012151111000000001,-0.050290363,0.001876334,0.008089816,0.10454532,0.007023058,0.033860823,-0.009558601,0.02065182,0.016412327,-0.11699305199999999,-0.002385247,0.006137914,-0.014711868999999999,0.030891500000000002,-0.119579835,0.328670474,1.183900381,2.056735716,-8.402763822999999,-7.40000161,-8.425591705,-8.747386467,-10.12834035,-7.312498978,-6.9656375729999995,-4.397539683,-1457.467917803675 -3550,3550,E210V,0.094897041,0.09651764199999999,-0.011035055,0.027370832,-0.1782236,-0.051246006,-0.000451825,0.190245907,0.034669544,0.056379266,0.13665601800000002,0.000634062,-0.022704172,0.023163938,0.031577726,0.005762714,-0.36220991399999997,1.150298002,2.5692927709999998,-0.290004659,-0.232349403,-1.070384277,0.098878334,-0.69243856,0.446270615,-2.018290134,0.11553045,-1459.4748322945088 -3551,3551,E210Y,-0.000453559,-0.065894385,0.04450931599999999,0.031305032,0.35579066299999995,0.026906001000000002,0.08020906,-0.081116178,0.11135296800000001,0.06331163599999999,-0.195100405,0.058407605999999994,0.030611025,-0.009979298000000001,0.072589362,0.005709788,0.705871537,1.206364278,2.599664057,-6.292568446000001,-4.966194641,-5.797284477000001,-6.646789093,-8.34468145,-5.707892571,-5.604529161,-2.452820746,-1453.7277743476443 -3552,3552,A211C,0.165597556,-0.330561522,0.065873025,-0.020063676000000003,-0.286941361,-0.090317373,-0.051380898,0.382576009,-0.034893658,0.009849609,-0.670972653,0.064905899,0.06684015,-0.015475902,-0.02465145,0.018601742,-0.592484464,1.27048636,2.589348045,-7.11529586,-7.338139877000001,-8.034015656000001,-6.991797073,-7.235534256,-5.976992439,-6.3886150289999994,-4.753808458,-1458.3944288636558 -3553,3553,A211E,0.040779795,-1.2e-05,0.073465257,0.076926871,-0.0032463659999999997,0.021890841,-0.021297886000000002,0.102857475,-0.0018870129999999999,0.07817866,-0.078202738,0.13944372300000002,0.00748679,0.033456118,0.12039762300000001,0.098256785,-0.104749516,1.04450295,2.768537148,-1.9195632230000002,-1.505683266,-2.565458199,-2.347578384,-1.288588577,-1.89050769,-2.335297227,-0.727801826,-1453.512199218385 -3554,3554,A211D,-0.052752260999999995,0.075491213,0.118134646,0.085846757,0.149351808,0.039283617,-0.042487185,-0.063017337,-0.003985289,0.077046036,0.07393639,0.145437985,0.090831306,0.132574413,0.039119101,0.054618954000000004,0.24408466199999998,0.963688861,2.732984773,-1.243541087,-0.643802406,-1.7563286359999999,-1.28115126,-1.342334023,-1.194089111,-2.315357272,-0.683619103,-1460.616531131789 -3555,3555,A211G,-0.012761912,0.07680614599999999,0.054519424000000004,0.052699065,0.047543237,0.001702951,-0.037532417,0.012008594,-0.046374032,0.072329323,0.081282968,0.070716058,0.03832279,0.042426329000000006,0.06297180000000001,0.04937324,0.045713233,1.055561019,2.6023994790000002,-2.150582678,-1.970054405,-2.5171848530000003,-1.162150978,-3.37373645,-1.729786705,-2.304643025,-0.134907993,-1466.0322410534136 -3556,3556,A211F,-0.088204586,0.016797164,0.019205139,0.013035036000000002,-0.547828864,-0.07307683599999999,-0.182317477,0.005908305,-0.049134097,0.006574018,0.02702031,0.109998666,-0.071588389,0.11859591300000001,-0.092525842,-0.30303965899999996,-0.792618068,0.777656075,1.582281234,-8.376490187,-10.01766257,-8.919344849,-7.219008667000001,-7.61880751,-8.107627342,-6.234884762999999,-4.033410673000001,-1461.4917383636348 -3557,3557,A211I,-0.001845151,0.19721603199999999,0.052569600999999994,0.033817436,-0.664675484,0.013229461000000001,-0.030018545,0.026328242999999998,-0.0063951730000000005,0.004890238,0.389541825,0.044487994,0.060651208,0.021221662000000002,0.04641321,-0.774315678,-0.55503529,0.591209788,1.364152618,-5.818475171,-5.902504601,-6.63425042,-4.723353653,-6.4080243679999995,-5.424242812999999,-5.427792033999999,-4.3564703510000005,-1453.999319594819 -3558,3558,A211H,0.002109154,0.127979186,0.060033759000000006,0.07203824,0.10639186099999999,0.026572092000000002,-0.07414577,0.078364077,-0.05351316,0.10232096,0.153637411,0.102401485,0.017666033,0.074423284,0.069653195,0.053387639,0.159396083,0.954870595,2.808905419,-4.43532399,-3.9612735669999997,-4.803433846,-4.162707008,-5.694847221,-3.5543583069999998,-2.920817997,-1.568895044,-1455.711405751761 -3559,3559,A211K,-0.016473945,0.04691903,0.004852124,0.1012606,0.00473626,-0.16906208399999997,-0.113662776,0.080714886,-0.092599791,0.30719869899999996,-0.213360639,0.136327605,-0.126623357,0.161315268,0.041205932,0.088229028,-0.078756508,1.106945548,2.948048726,-4.749191087,-5.8721646960000005,-4.997145584,-5.83884774,-5.190861092,-1.846936325,-5.2269561,-1.26059231,-1452.2236657007597 -3560,3560,A211M,0.141218393,0.119000724,0.187974355,0.211863595,0.299713579,0.00877512,0.09013838,0.192298405,0.11677933199999999,0.18587041699999998,0.052131030999999994,0.226739562,0.149209147,0.144181833,0.279545356,0.11166199999999998,0.487765158,0.86488049,2.984459774,-4.074415623,-4.497206955,-4.343359215,-3.843191231,-4.080276993,-3.608043724,-3.790586577,-3.4065451,-1456.3880595737137 -3561,3561,A211L,-0.00962619,0.07696012599999999,0.056369750999999996,0.009543409000000001,0.08435156,0.008232106999999999,-0.057288505999999996,0.038036127,-0.059179544,0.020111988,0.133808263,0.075556707,0.037182794,-0.010385142,0.029471959,0.0018480870000000002,0.166855032,1.082920395,2.6377671869999997,-5.402906206,-6.025229111,-5.543777405,-4.858358162,-6.31787484,-4.269291512,-5.492110319,-1.865964711,-1453.5691927615553 -3562,3562,A211N,-0.081826003,-0.049166152000000005,0.045194104000000006,-0.025987878,0.007469645,-0.059988837999999996,-0.120313377,-0.043338629000000004,0.129151681,-0.06764780299999999,-0.030684500000000003,0.070755072,0.019633136000000002,-0.10438676599999999,0.05241101,-0.076015365,0.09095465400000001,1.344865886,2.240470862,-2.144776646,-2.626895439,-2.747247345,-1.8574449080000002,-2.315781029,-1.176514511,-2.370767461,-0.8012992059999999,-1463.5215950375423 -3563,3563,A211Q,-0.131027262,0.08314495400000001,-0.037549245,-0.0019919829999999997,0.085666892,0.011033528999999999,-0.19013506300000002,-0.07191946,-0.027119261000000002,0.072593818,0.09369608900000001,0.043757473,-0.118855962,0.048014839000000004,-0.051998804,0.06554199299999999,0.10579179,1.2485966640000001,2.964181393,-3.578374222,-3.71016494,-4.322492805,-3.7272695010000003,-3.931403519,-2.200540344,-3.971425196,-1.17057196,-1455.0700986450538 -3564,3564,A211P,0.07737986599999999,-0.17221531899999998,0.043309608,-1.143943523,-1.6214594709999999,-0.074692645,-0.027627477999999997,0.18238721,-0.043907176,0.038788508,-0.383219146,0.040794409,0.045824807,-0.995269783,-1.292617263,-1.69100268,-1.551916261,2.797967356,2.121657129,-6.497865517999999,-5.8093539729999994,-6.544515381,-6.1851129,-8.009903549,-5.940441787999999,-5.664476175,-5.075258983,-1455.4665773482993 -3565,3565,A211S,0.080007247,-0.098643823,0.054251319000000006,0.017855886,-0.057107732,0.009393837,-0.004738223,0.164752717,-0.03949482,0.001128053,-0.19841569899999997,0.010390116,0.098112522,-0.044411074,0.080122846,-0.019927625,-0.09428783800000001,1.27419062,2.5090696869999998,-2.9993519710000003,-3.468783981,-3.1158116380000003,-2.505376686,-4.054406525,-1.8523810269999998,-3.646082357,-1.7870187819999999,-1460.2592987120152 -3566,3566,A211R,0.021456189,0.00490232,0.050610907000000004,0.066860696,0.028937467,0.031171065,-0.051059065,0.093971443,-0.023898274,0.072513825,-0.062709186,0.08638229,0.014839523,0.059096865,0.074624527,0.07122327,-0.013348336,1.168924577,2.9542246010000004,-4.138032835,-4.393217674,-5.5323741989999995,-3.853051537,-5.59099025,-1.320530518,-2.8771605460000003,0.026331551,-1454.6165929846466 -3567,3567,A211T,-0.02376757,0.09466592199999999,0.03166356,0.026301236000000002,-0.316316504,-0.032809175,-0.052790684000000004,0.005255544,-0.033685606,0.108324398,0.081007446,0.04661335,0.01671377,-0.0030917970000000003,0.055694268,-0.270891007,-0.36174200100000004,1.04127448,1.748284181,-3.439151752,-3.894630836,-3.415350777,-2.771771118,-4.492446243,-2.621559784,-3.675758358,-1.821075286,-1458.1921322760172 -3568,3568,A211W,0.050143737,-0.162096842,0.053618861,-0.013974251000000002,-0.8102898940000001,0.038888442,-0.118045516,0.21833298899999998,-0.015609413999999999,0.069370451,-0.393564134,0.07052979599999999,0.036707925,0.022107977999999997,-0.050056479,-0.384344599,-1.236235188,0.9133672979999999,1.577427361,-8.729997198,-9.066754257000001,-10.50896852,-8.368019936,-8.706284088,-6.99995919,-6.259128764,-4.675589372,-1459.908874266781 -3569,3569,A211V,-0.000675747,0.105957516,0.046432544000000006,0.080167616,-0.649735281,-0.010412309,-0.032570517,0.031219023,-0.071782057,0.117682649,0.094232383,0.123897276,-0.031032188,0.08503850800000001,0.07529672400000001,-0.699217822,-0.600252739,0.350906775,1.341018564,-5.881790659,-5.886832954,-6.439836929,-5.573355583,-5.858073151,-5.650854675,-5.953061484,-4.6076950519999995,-1455.835979167372 -3570,3570,A211Y,0.054087475999999995,-0.010895512,0.157771256,0.077594306,-0.353034012,-0.045219398,-0.074972939,0.18314789,-0.047128115,0.177455406,-0.19924643,0.16887243,0.146670081,0.032358028,0.122830584,-0.031396804,-0.67467122,1.321109761,2.547728722,-8.209191608,-9.055009644,-8.795346016,-7.325202705,-7.666591437999999,-8.203808235,-6.169640514,-3.9043921839999998,-1456.1450986326672 -3571,3571,D212A,0.067048026,-0.007268238000000001,0.085416434,-0.048719385999999996,-1.4509381430000001,-0.060816565999999996,0.073489956,0.060606096,0.034881477,0.041216548,-0.055753023,0.0018027070000000002,0.16903016,-0.137268515,0.039829744,-1.6428547619999998,-1.259021523,0.7982884370000001,1.320195467,-9.137807828,-8.047322449,-7.5218458560000006,-11.19227575,-8.969851509,-9.957743576,-5.657073737,-0.268618658,-1442.2750700311735 -3572,3572,D212C,0.042196129000000006,0.118190169,0.06767303200000001,-0.6951301940000001,-2.102952115,-0.147179841,0.020206272,0.064185986,-0.023335482,0.078705861,0.157674476,0.061585163,0.07376090099999999,-0.48452210799999995,-0.905738279,-2.338430451,-1.867473779,1.506708722,1.282049832,-9.883662787999999,-9.760578873,-9.705652748,-11.28704755,-9.791674644,-8.873360123,-4.954221243,1.147943095,-1464.6752424947917 -3573,3573,D212E,0.02848791,0.106854125,0.06504088200000001,-1.12509824,-1.56686785,-0.147937816,0.059278553,-0.002302733,-0.017086531999999998,-0.0033512159999999997,0.217059466,-0.022958282000000003,0.15304004599999999,-1.177929252,-1.072267227,-1.8065283140000001,-1.327207385,2.267425571,1.596148081,-8.270353557,-8.041598907000001,-8.206011154,-6.930916565,-8.796123611,-9.377117546000001,-7.448054367999999,-2.675542949,-1448.6036258353852 -3574,3574,D212G,-0.029872316,0.050154026,0.097812251,0.172463174,-1.068630148,-0.065869918,0.040584287000000004,-0.100328919,0.040260254,0.059426037,0.040882014,0.003400339,0.192224163,0.03895267,0.305973677,-1.137002783,-1.0002575120000001,0.628253195,1.336712476,-6.312953584,-5.602363861000001,-6.317978424,-6.742556625,-6.794542015,-6.107326996,-4.812017345,-0.286854059,-1448.3230876144953 -3575,3575,D212F,-0.04949869,-0.280926648,-0.104026414,-1.580677415,-1.875844696,0.148430416,-0.147842267,0.048844887999999996,-0.020506192,-0.043323744000000004,-0.518529551,-0.168936328,-0.039116500000000005,-1.8956824859999999,-1.265672344,-2.193288329,-1.558401063,1.065252403,0.6873702759999999,-16.61079407,-17.04480203,-17.14919669,-15.07832938,-17.44860095,-16.3330413,-9.887251498,-6.66660981,-1456.0691004050896 -3576,3576,D212I,0.031287058,-0.232358867,-0.17885083,-1.42118526,-1.5658375430000002,0.18187058399999997,0.028829212000000003,0.033744903,0.078373414,0.020063235,-0.484780968,-0.343093087,-0.014608573,-1.485508021,-1.3568624980000001,-1.7831138640000002,-1.348561221,3.57419437,2.593422806,-13.77856117,-12.79292319,-12.60661906,-15.044749599999998,-15.120381900000002,-13.32813211,-6.87835414,-0.660732642,-1451.0215444695204 -3577,3577,D212H,0.062273657999999996,0.026584936,0.043736705,-1.340260784,-1.6831580380000002,-0.11879501599999999,0.048369047000000005,0.076178268,0.038575952999999996,0.006374426999999999,0.046795445,-0.007005447,0.094478856,-1.2648137990000001,-1.415707769,-2.02105749,-1.345258585,2.511301559,1.6892451080000002,-11.02462231,-11.4639108,-12.11021054,-9.97693502,-10.46261859,-11.109436599999999,-7.164422184,-2.41375865,-1449.4091198085807 -3578,3578,D212K,0.01543215,0.060548834,0.017496813,-0.287656941,-1.616297616,-0.259782478,-0.085665975,0.116530274,0.073574531,-0.009545318,0.130642985,-0.22058809699999998,0.255581722,-0.48169281799999997,-0.093621063,-1.925426696,-1.307168536,1.754047212,1.416026293,-13.06921737,-12.46810815,-15.33546486,-13.26565019,-12.46157943,-11.81528421,-7.40848703,-2.7014090019999997,-1446.3404159471393 -3579,3579,D212M,0.137263212,-0.08621225099999999,0.038204155,-1.4615968559999999,-1.668718507,-0.009163435,0.09919920800000001,0.175327215,-0.053298705,-0.214931398,0.042506895999999995,-0.195329289,0.271737599,-1.51958781,-1.403605901,-2.118223649,-1.219213365,2.728808771,1.71184133,-14.82975552,-13.31465385,-14.11977993,-16.10816054,-15.73338357,-14.87279971,-8.098658947,-3.30049966,-1444.5452055102214 -3580,3580,D212L,0.046244272999999995,0.008860326,-0.145093688,-1.705730253,-2.467021641,0.07879159,0.044853788,0.047634758,-0.062271453,0.015396143999999999,0.002324508,-0.278919765,-0.01126761,-1.8755259919999998,-1.5359345130000002,-2.54110862,-2.392934662,1.290198693,0.7126342290000001,-15.45833308,-14.98532079,-15.20282879,-16.27529118,-16.58074883,-14.24747579,-7.626242221,-2.79669284,-1444.836122191511 -3581,3581,D212N,0.035139747,-0.039206784,0.17803315600000003,0.242119395,-0.990291815,-0.117875655,-0.077573298,0.14785279199999998,0.007094474,0.17416020000000001,-0.252573767,0.104064944,0.252001368,0.143731633,0.340507157,-1.114107083,-0.866476547,0.735274658,1.351840776,-3.3921070560000004,-3.5995731280000003,-3.415153984,-2.7888054660000003,-2.992302925,-4.164699776,-3.371026388,2.712400166,-1465.7497300012037 -3582,3582,D212Q,0.425552231,-0.344646103,0.041474325,0.167395392,-1.0833758279999999,0.024292058,0.056585736,0.794518726,0.134489356,0.032849679,-0.722141884,-0.024978517000000002,0.10792716599999999,0.071681701,0.263109083,-0.8818595140000001,-1.284892141,0.5942557279999999,1.353271186,-11.04012304,-11.500037800000001,-12.88237779,-9.906479477000001,-12.89137988,-8.020340279,-6.016136191,2.432267668,-1463.383364292793 -3583,3583,D212P,0.114636793,-0.098859339,0.056577642000000004,0.017671171,-1.765575956,-0.183885842,0.042944517,0.18632906899999999,0.073838314,0.0228327,-0.220551377,-0.03054781,0.143703093,-0.068259573,0.103601914,-1.747850278,-1.783301634,0.598780281,1.305529474,-13.52414235,-13.00648797,-13.50836068,-14.06186008,-13.66988313,-13.37411991,-6.5205254,-1.521214627,-1452.5117863989435 -3584,3584,D212S,0.114062866,-0.070586778,0.088390618,0.14898735,-1.350442793,-0.145487229,0.06719185700000001,0.160933875,0.044913540999999994,0.067981996,-0.209155552,-0.013048455,0.18982969100000002,0.015894369,0.282080331,-1.424875031,-1.276010554,0.6095640210000001,1.3189698109999999,-7.369889467999999,-7.559662476000001,-6.881417404,-8.116803871,-5.955345497000001,-8.336218094,-4.661864568,1.196876562,-1446.8946843869053 -3585,3585,D212R,0.16278377300000002,0.011739728,0.10097593199999999,-0.625320886,-2.395898308,-0.06380517299999999,0.067106779,0.258460766,0.059195639,0.020664386,0.00281507,0.020443164,0.18150870000000002,-0.57446387,-0.676177901,-2.219024203,-2.572772412,1.692525312,1.336529886,-13.46444152,-14.46093436,-14.51072019,-14.31182519,-12.80359941,-11.23512846,-7.789945976,-2.719851725,-1444.0572447418235 -3586,3586,D212T,0.236492311,-0.346922513,0.08565086699999999,0.13004678,-1.4328847669999998,-0.085642828,0.010008491,0.46297613,0.10393874800000001,-0.018308037,-0.675536989,-0.003544914,0.174846647,0.027634907,0.23245865300000002,-1.405633537,-1.460135996,0.955470413,1.348777149,-9.206155347000001,-7.8109485020000005,-8.46278669,-11.06114219,-10.46770844,-8.228190918,-6.00124858,2.0399797769999997,-1452.7701396397315 -3587,3587,D212W,0.146557348,0.231281376,-0.093678712,-1.374198275,-1.9703955519999998,0.054259111,0.15108901800000002,0.14202567800000002,0.050241887,0.17644296199999998,0.28611978899999996,-0.20844486899999998,0.021087446,-1.634161032,-1.1142355179999999,-2.23279687,-1.7079942330000002,1.327769763,0.759061755,-15.83491338,-15.70733674,-16.17983297,-15.55259409,-16.483864699999998,-15.25093839,-9.887251498,-6.66660981,-1460.068607531488 -3588,3588,D212V,0.009144911,-0.076412805,0.036872162,-0.43643010200000004,-1.8490246830000001,-0.038434612,-0.009314019,0.02760384,0.050241887,0.005326944,-0.158152554,-0.05654399,0.13028831400000002,-0.45423142899999996,-0.418628775,-1.801055294,-1.896994071,1.702697449,1.4374540690000002,-13.10027038,-11.85069236,-12.40362946,-14.75538599,-13.65257039,-12.83907369,-6.2536905670000005,-0.074646801,-1450.1996124447323 -3589,3589,D212Y,0.050627088,-0.208969286,-0.091051113,-1.770972205,-1.9780938559999999,-0.022259684,0.020775838999999997,0.080478337,-0.056091605,-0.088230511,-0.32970806,-0.147747029,-0.034355197000000004,-1.4237008709999999,-2.118243538,-2.323366705,-1.632821006,1.357390435,0.80884922,-14.87110054,-14.12619893,-16.9445811,-13.23498289,-15.62986945,-14.41987035,-8.999293042,-4.316477437,-1448.4357228260487 -3590,3590,K213A,0.013259035,-0.178596377,-0.033302257,-0.09921299300000001,-0.15013473,0.010471139,-0.032336336,0.058854406,0.0034436490000000004,-0.069134057,-0.288058697,-0.110557455,0.043952940999999995,-0.185825858,-0.012600128,-0.085898772,-0.214370688,1.355691652,2.262272709,-5.529450345,-5.83233596,-5.244788048,-5.320082886000001,-5.891895622000001,-5.358149208,-3.5839231760000003,-0.946880266,-1454.438921127934 -3591,3591,K213C,0.030701275,-0.155489534,-0.014017948,-0.063654057,-0.407447461,-0.016037957,0.009640707,0.051761842999999995,-0.059139620999999996,-0.116993838,-0.19398523,-0.085254808,0.057218912999999996,-0.152884698,0.025576584,-0.29342034899999997,-0.521474572,1.7298564630000002,2.197669006,-9.205811482,-9.05472847,-8.584701477000001,-9.826750191,-9.748060172999999,-8.814817101000001,-7.7361212120000005,-5.450530175,-1445.2665536282584 -3592,3592,K213E,0.007355197,-0.141519327,-0.036711249,-0.102793969,-0.9269661109999999,-0.027090994,-0.024548187000000003,0.03925858,0.092541735,-0.072850159,-0.21018849399999998,-0.116757481,0.04333498400000001,-0.139621356,-0.065966582,-0.7440457140000001,-1.1098865070000001,1.5971406330000002,1.7444851330000002,-4.764894188,-5.450195244,-4.8130348210000005,-4.5944560999999995,-3.814447098,-5.152337677,-3.6569701880000003,-0.757827198,-1457.3560839253478 -3593,3593,K213D,-0.01676274,-0.106221292,-0.32591976100000003,-1.631917997,-1.568932922,-0.092840669,-0.01461266,-0.01891282,0.078199049,0.024545882999999998,-0.236988466,-0.253576779,-0.398262743,-1.487169811,-1.7766661830000001,-1.6965020030000002,-1.441363841,3.737037393,2.792058975,-7.606757166,-7.939579437000001,-7.386201324,-7.570781333999999,-7.667330933,-7.469892799,-6.045118872000001,-2.20709935,-1448.1332197482698 -3594,3594,K213G,-0.011407198,-0.106674859,-0.015774903,-0.071999245,-0.72143042,-0.014105814,-0.049016885999999996,0.02620249,-0.061659332000000004,-0.040447127,-0.17290259100000002,-0.073490296,0.041940491,-0.126312846,-0.017685644,-0.604697935,-0.838162905,1.5832389059999998,1.7981661830000002,-6.764265207999999,-7.520170097,-6.5204290160000005,-7.200283257000001,-7.120248322,-5.460195351,-4.537027693,-2.468453078,-1448.3708589612506 -3595,3595,K213F,-0.031636376,0.052864968,0.029665947,-0.006411961,-0.338193495,0.016994781,-0.056583441,-0.006689311,0.003190878,0.08891852300000001,0.016811413,-0.04235224,0.10168413400000001,-0.048531933,0.035708012000000004,-0.320750943,-0.35563604600000004,1.4439980590000001,1.9722202640000002,-9.910245035,-9.116238312,-9.718779839,-10.08842078,-9.614059418,-11.01372682,-7.162237796,-3.196131357,-1445.359352747444 -3596,3596,K213I,-0.055547307000000004,-0.1818019,0.006204691,-0.11166310900000001,-0.18181197899999998,0.125034358,-0.120336027,0.009241413,0.017201591999999998,0.004909915,-0.368513715,-0.046372305999999995,0.058781687,-0.17351000600000002,-0.049816211,-0.142917385,-0.220706572,1.404441966,2.15873831,-6.835935056,-7.2536301420000004,-6.580871498,-7.843138924,-6.084800247,-6.417234467,-5.114658545,-2.097765929,-1453.372368789278 -3597,3597,K213H,-0.017596653,-0.143980558,0.00662126,-0.09725712199999999,-0.24709088399999998,0.016182171999999998,-0.051418142,0.016224836,-0.016676793999999998,-0.061928829000000005,-0.22603228600000003,-0.079076865,0.092319384,-0.148360775,-0.046153467999999996,-0.17602759399999998,-0.318154173,1.582208888,2.219333444,-5.230429818999999,-5.612887886,-4.48960363,-5.108792053,-5.642150063,-5.298715462,-5.565565725,-1.803216797,-1449.2892910786904 -3598,3598,K213M,0.006604575,-0.15942019699999999,0.010453651,-0.087290634,-0.081841882,0.016794286000000002,-0.032583164,0.045792314,0.042558693,-0.045258125,-0.273582268,-0.040088252000000005,0.060995553,-0.143273821,-0.031307446,-0.001696465,-0.161987298,1.2318136990000002,2.464042643,-6.675834474,-6.421432082999999,-7.11862001,-7.143290604,-5.766055077000001,-6.929774597000001,-6.304795747999999,-3.081565898,-1457.8791187987663 -3599,3599,K213L,0.025181031,-0.086228993,-0.028927476,-0.061253981,-0.065453657,0.015990426999999998,0.008466267,0.041895795,-0.032267474,-0.057560413,-0.11489757199999999,-0.091096869,0.033241917999999995,-0.150545396,0.028037435,-0.048820808,-0.08208650599999999,1.376014197,2.397550292,-5.935441881,-6.614023949,-6.496507126,-6.481012634,-4.81433976,-5.271325935,-4.674511744,-1.8180383919999998,-1454.79465246154 -3600,3600,K213N,-0.089979663,-0.012241861000000001,-0.012068771,-0.060090547,-0.186996305,0.086103208,-0.061134047000000004,-0.118825278,0.085260904,-0.021159107000000003,-0.003324615,-0.024470464,0.00033292300000000005,-0.033508853,-0.086672241,-0.136925546,-0.237067064,1.3746676340000001,2.212412636,-4.832694496,-4.976177658,-4.616900757,-4.787181488,-4.922033508,-4.86117907,-4.501866209,-2.57157995,-1452.5299742771313 -3601,3601,K213Q,-0.015278683999999999,-0.076341173,-0.008285411999999999,-0.055855318,-0.025008602,0.09371028599999999,-0.047910956,0.017353589,-0.063216884,0.009541311,-0.162223657,-0.08714373,0.070572907,-0.082309431,-0.029401205,-0.007278849,-0.042738354000000006,1.261582466,2.575244322,-1.9786707019999998,-2.288034515,-2.142881973,-1.5027694930000002,-1.9847999040000002,-1.9748676219999999,-2.508709203,0.117217461,-1457.4196504834108 -3602,3602,K213P,-0.024254219,-0.052874837,-0.008872558000000001,-0.7485809520000001,-1.6882376590000001,-0.030568129,-0.050218884000000005,0.0017104470000000001,0.005628591999999999,-0.054400883,-0.05134879,-0.081875193,0.064130078,-0.698163051,-0.798998853,-1.9208966969999999,-1.455578621,1.88781494,1.446317176,-7.686393495,-8.61217141,-7.046088821000001,-8.342218857,-8.120347824,-6.311140564,-5.160410751000001,-1.688346359,-1440.288551535923 -3603,3603,K213S,-0.033554747999999995,-0.112730859,-0.054055368,-0.08523899800000001,-0.210462363,0.022463145,-0.049779733,-0.017329763,-0.053209941,-0.073735009,-0.15172670800000002,-0.127771128,0.019660392,-0.146644745,-0.023833251,-0.195972498,-0.224952227,1.601294,2.249501175,-4.842875447,-5.221908378999999,-4.363752487,-5.97295192,-4.4792276310000005,-4.176536819,-4.0569065669999995,-1.16667883,-1451.497518661432 -3604,3604,K213R,0.004328584,-0.116185645,-0.017120396,-0.071587252,-0.106634552,0.032437935,-0.030872697,0.039529864,-0.003409626,-0.048121587,-0.18424970300000001,-0.07952947099999999,0.045288679000000005,-0.113395347,-0.029779157,-0.043313758,-0.169955346,1.341771716,2.396205698,-2.109068019,-2.194177094,-1.511185623,-2.21711116,-2.704723122,-1.918143097,-2.253224271,-0.381619386,-1449.636276407633 -3605,3605,K213T,-0.003800431,-0.11814950199999999,-0.042123152999999997,-0.107751964,-0.34256764799999995,-0.030608528,-0.034572454,0.026971593,0.00897727,-0.069201707,-0.167097296,-0.11203478900000001,0.027788484,-0.15685553,-0.058648398,-0.317751508,-0.367383788,1.880909051,2.3076284780000003,-4.364389534,-4.624284889,-3.9887894360000002,-5.025066475,-4.835754486,-3.348052383,-3.786917955,0.5366438379999999,-1455.7124721417204 -3606,3606,K213W,-0.011197468,-0.11009455900000001,-0.001042801,-0.08644534300000001,-0.888566052,0.012762207,-0.047339049,0.024944114,-0.001451958,-0.025156854,-0.19503226399999998,-0.04527788,0.04319227900000001,-0.14281291699999998,-0.030077769,-0.654186269,-1.122945835,1.475636515,1.739286291,-9.179618146000001,-8.804640762,-8.873613387999999,-9.950220657000001,-9.740918976,-8.528696945,-7.32498848,-4.7766310260000004,-1449.2268002163619 -3607,3607,K213V,-0.00819853,-0.13202287,0.0026572909999999996,-0.060309681,-0.120524299,0.025235333,-0.060945180999999994,0.044548120999999996,0.09733406,-0.040569377999999996,-0.223476361,-0.074666039,0.07998062,-0.111723373,-0.008895989,-0.028620736,-0.212427862,1.437898184,2.544978656,-5.829983011,-6.673829963999999,-5.570718987,-6.193807259,-5.361053711,-5.350505135,-3.977251865,-0.8504253070000001,-1456.8199306237511 -3608,3608,K213Y,-0.014506305,-0.020949266,-0.016262078,-0.086895418,-0.370230613,-0.07390860099999999,-0.033598522,0.004585913,0.076938397,0.043812637,-0.085711168,-0.081810806,0.049286650999999994,-0.125739772,-0.048051063,-0.27119034399999997,-0.46927088100000003,1.5859954440000001,2.1229941,-9.269448645,-8.94075174,-9.488941994,-9.553125488,-9.203682014,-9.160741989,-6.589973815,-2.487493147,-1440.4503995119594 -3609,3609,V214A,0.103469719,-0.06806686299999999,0.006739146999999999,-0.041598242,-0.908327702,-0.09338211,-0.030418188999999998,0.237357627,0.040009223,-0.005170654,-0.13096307199999999,0.057627902,-0.044149609000000006,-0.025906982999999998,-0.057289501,-0.701972595,-1.114682809,0.6922216990000001,1.391063252,-9.425958092,-11.22896339,-9.883159546,-9.222745834,-10.04943343,-6.745488251,-7.318838417,-3.2048203280000003,-1447.4685741770081 -3610,3610,V214C,0.128454407,-0.013210372,-0.006862655,-0.049724385999999995,-1.214542094,-0.169356764,-0.049352138,0.306260952,0.086995111,0.060512208,-0.086932952,0.06733347599999999,-0.081058785,0.009478475,-0.10892724599999999,-1.335413716,-1.0936704720000001,0.574288409,1.32060653,-14.14139774,-14.95517565,-13.69034844,-16.29258829,-14.51256151,-11.25631479,-8.042179142,-3.360444673,-1457.2638230342418 -3611,3611,V214E,0.032427615,0.028456857000000002,-0.013368413,-1.339504054,-2.109988078,-0.24998505699999998,-0.088134327,0.152989556,0.09789304900000001,0.072323169,-0.015409455,0.06617946,-0.092916285,-1.15709362,-1.5219144880000002,-2.147511496,-2.07246466,2.159376204,1.44182232,-14.87652119,-17.13341249,-13.47086801,-16.36504733,-15.01292077,-12.40035735,-8.076400778,-3.2977796130000003,-1445.7410140330903 -3612,3612,V214D,0.196656827,0.008466308,-0.812161448,-1.635626594,-2.437506033,-0.181755814,-0.016722644,0.41003629700000005,0.07109362799999999,0.006510743,0.010421871999999999,-0.7933696379999999,-0.830953257,-1.628462546,-1.6427906419999998,-2.567727899,-2.307284166,2.309067694,1.166332926,-14.09325238,-16.59904484,-12.59197234,-16.41132438,-12.82650069,-12.03741968,-6.62172962,-1.371819205,-1450.5318841268308 -3613,3613,V214G,0.135999666,0.125165133,-0.0021961570000000002,-0.026279262999999997,-1.505191289,-0.141613456,-0.021778916000000002,0.293778247,0.085887579,-0.007253233,0.257583499,0.050881199,-0.055273512999999996,0.020696567,-0.073255093,-1.733879823,-1.276502754,0.8861056270000001,1.316093513,-14.08940724,-16.32003336,-13.74047269,-14.54197408,-14.23210054,-11.61245554,-8.0828271,-3.968211756,-1438.4482810492627 -3614,3614,V214F,0.153119801,0.01782571,0.011464809,-0.201724934,-1.659114328,-0.11851063,-0.02972592,0.335965521,0.086995111,0.060206172999999995,-0.024554753999999998,0.098082042,-0.075152425,-0.11401696800000001,-0.2894329,-1.9827012469999998,-1.335527409,0.834207652,1.301325903,-12.9975101,-12.42374341,-12.266120599999999,-15.80780328,-13.42445661,-11.06542662,-6.61677546,-0.232627479,-1459.719338081777 -3615,3615,V214I,0.19241111,0.011660193999999999,0.035006453,-0.043875689,-0.826021427,0.094481436,0.020544786000000002,0.364277433,0.113342206,-0.06007017,0.083390558,0.017617798,0.052395107,-0.086320422,-0.001430955,-1.201677035,-0.450365819,0.969217636,1.374080915,-5.329401816,-5.0905515669999994,-5.38318959,-5.521711868,-5.9283785170000005,-4.723177536000001,-5.85885611,-1.10919555,-1455.8906920459121 -3616,3616,V214H,0.164253492,-0.051812403,-0.045344207000000004,-0.005308875,-1.462711156,-0.155865585,-0.048269779000000006,0.37677676299999996,0.12175721699999999,0.036396937000000004,-0.140021742,0.04080411,-0.131492524,0.078917297,-0.089535046,-1.723670917,-1.201751394,0.63065412,1.307369422,-15.09786283,-15.31813455,-12.79859322,-18.93543587,-15.74435675,-12.69279376,-7.774933309,-2.388515249,-1453.9996089381166 -3617,3617,V214K,0.09647540800000001,0.187257332,0.039240734,0.011664635,-1.159835975,-0.179984786,-0.054419975999999995,0.247370792,0.098657249,0.079194421,0.295320243,0.10572986699999999,-0.027248400000000002,-0.047426376,0.07075564599999999,-1.685661734,-0.634010216,0.6170794039999999,1.3087740540000001,-14.28457821,-14.45524024,-13.02119846,-15.77273214,-15.08670715,-13.08701306,-8.687305182000001,-4.468006979,-1438.2855104124174 -3618,3618,V214M,-0.014596901,0.125501698,0.017432943,-0.114936464,-0.464651373,-0.12101261099999999,-0.06604575,0.036851947999999995,0.086607953,0.023636742000000002,0.22736665399999997,0.061555162000000004,-0.026689276,-0.105057063,-0.124815864,-0.363081179,-0.5662215660000001,1.510963913,1.967150126,-9.869516022,-9.845264664,-9.777039917,-9.475054024,-10.80744755,-9.442773956,-7.365516443,-3.0221813689999997,-1451.4122837125324 -3619,3619,V214L,0.092944827,0.017106408,-0.029466803,-0.0074057490000000005,-0.878103451,-0.113196462,-0.072729657,0.25861931,0.08621499099999999,0.007615047,0.026597767999999997,0.052232889000000005,-0.111166495,0.048011224000000005,-0.062822722,-0.872629788,-0.883577114,0.57354371,1.350739897,-6.695607882999999,-6.817189078999999,-7.052485435,-7.1914408110000005,-6.801784851,-5.615139236,-5.341176435,-0.7693771220000001,-1444.8114589583129 -3620,3620,V214N,0.068592293,3.35e-05,-0.033052461,-0.039471948,-1.332146477,-0.140118209,-0.064374276,0.201558861,-0.009943333,-0.01957715,0.019644071000000003,0.033668362,-0.099773283,0.019130553,-0.09807444800000001,-1.155663248,-1.508629706,0.844150143,1.359234761,-13.27218712,-14.75878712,-13.20789846,-15.36566426,-11.46681667,-11.56176911,-5.967597632,-1.252213472,-1441.0095709930174 -3621,3621,V214Q,0.11770275599999999,-0.010632579,-0.034547932,-0.075363309,-1.324416663,-0.13894995400000001,-0.047897580999999995,0.283303093,0.08573288800000001,-0.013698759,-0.007566398,0.019345607,-0.088441471,-0.103763754,-0.046962863,-1.12575038,-1.523082945,1.052896566,1.399277726,-14.42652204,-15.88986733,-13.33045737,-15.43390808,-15.47941604,-11.99896137,-8.658005918999999,-3.79431225,-1446.1227159285918 -3622,3622,V214P,0.21113650399999997,-0.062503157,0.00463464,-0.110768725,-1.822061876,-0.15419074900000002,-0.07221206,0.49448506799999997,0.085030479,0.009944313,-0.134950626,0.056723919000000005,-0.04745464,-0.042409115,-0.179128335,-1.738514865,-1.905608886,0.6182098570000001,1.305969224,-13.01993227,-14.62165793,-10.995187800000002,-14.09270338,-12.68381815,-12.70629408,-6.686503849,-2.826672256,-1444.307655101642 -3623,3623,V214S,0.104075111,0.04629708900000001,0.009632855,-0.057298864000000005,-0.8589906820000001,-0.090693064,-0.03481711,0.24296733199999998,0.156909955,-0.053038651,0.14563282800000002,0.076468354,-0.057202645,-0.019105701,-0.095492026,-0.950696575,-0.7672847890000001,0.557047845,1.340162703,-11.28855412,-12.30323379,-11.07611539,-12.95657853,-9.981938995,-10.12490392,-6.399977597,-1.4769532109999999,-1440.638988467399 -3624,3624,V214R,0.144320888,0.129899359,-0.0027886390000000003,-0.023635369,-1.47282212,-0.11031474599999999,-0.04135916,0.330000936,0.07478641400000001,0.017457398,0.24234131899999997,0.062508309,-0.068085587,0.028402094,-0.075672832,-1.664344795,-1.281299445,0.622770105,1.309578704,-11.12683707,-11.56796969,-8.653530884,-11.838983599999999,-12.97199062,-10.60171056,-6.710822542000001,-2.305187905,-1435.1879442222416 -3625,3625,V214T,0.09886749,0.09626871199999999,0.018104244,-0.050957875,-0.246635617,-0.141841874,-0.014406513999999999,0.21214149399999999,0.08672168699999999,-0.006858077,0.1993955,0.011131893,0.025076595,-0.013599675,-0.088316075,-0.19384383,-0.299427404,1.278892809,2.035531171,-5.464224016,-6.614370201,-4.595389771000001,-5.547096565,-6.94885067,-3.615412872,-4.890531343999999,1.550308435,-1456.9470711704344 -3626,3626,V214W,0.07108893200000001,0.087615692,-0.048183923,-0.287164663,-1.630367752,-0.115633716,-0.089192719,0.231370582,-0.021112692000000002,0.026075148,0.149156236,0.050556217,-0.146924062,-0.095960555,-0.47836877,-1.6899437769999999,-1.5707917269999998,0.89689776,1.323301511,-14.154976300000001,-14.447575500000001,-13.13111323,-14.98182317,-13.9961329,-14.21823672,-7.827418092,-2.080117635,-1456.9818464140408 -3627,3627,V214Y,0.161194391,-0.020889706,0.001662453,-0.240661438,-1.394818299,-0.065146164,-0.027519221,0.34990800200000005,0.045804940999999995,-0.026984495,-0.014794917,0.058307807,-0.054982900999999994,-0.093495301,-0.387827574,-1.609997062,-1.179639536,0.723590018,1.316221535,-15.89596173,-15.99096864,-14.8390837,-19.35064449,-15.31967547,-13.97943635,-6.561899845,-0.82708322,-1449.1345326267183 -3628,3628,A215C,0.023562944,-0.013440298,0.070899622,-0.681506457,-1.5625656909999999,-0.094959911,0.075448236,-0.028322349,-0.016777615,-0.040324055,0.01344346,0.04469461,0.09710463300000001,-0.629959857,-0.733053057,-2.079637179,-1.045494202,1.706779949,1.3561865919999998,-10.98108636,-10.7267995,-12.53864843,-10.939690800000001,-10.19376569,-10.506527400000001,-6.966079927000001,-3.612432913,-1463.874238748569 -3629,3629,A215E,-0.042314189,-0.031344694,0.05873992,-0.437744951,-1.277329484,-0.132678514,-0.039097947,-0.045530430999999996,-0.061269467,0.01547167,-0.078161057,0.157584051,-0.040104211,-0.41002907200000005,-0.46546083,-1.626045037,-0.9286139309999999,1.58480219,1.443726488,-10.44732098,-10.23297678,-11.39757707,-10.73320893,-10.41976097,-9.453081168999999,-7.1900610160000005,-2.9862148389999996,-1441.9737919326872 -3630,3630,A215D,0.021827648999999998,0.048333825,-0.8345261070000001,-2.548238304,-2.091308436,-0.087369234,0.08702442699999999,-0.04336913,0.063152507,0.076344507,0.020323142,-0.750874292,-0.918177921,-2.289931955,-2.806544652,-2.162117476,-2.020499395,1.539064424,0.535776915,-10.96955668,-10.88245868,-11.41843651,-11.22696829,-10.97648267,-10.34343727,-5.599776493999999,-0.7365563079999999,-1448.590586323291 -3631,3631,A215G,-0.018948467,-0.0021354810000000003,0.045582685,0.005471770999999999,-0.42454654,-0.089318816,0.000140548,-0.038037482000000004,-0.033388117,0.013221221000000002,-0.017492182,0.11695004,-0.025784671000000002,0.002102707,0.008840834,-0.605429828,-0.243663252,0.819165363,1.443043045,-1.805307565,-2.155460876,-1.3877756730000002,-2.232794205,-1.500159409,-1.750347664,-3.028826243,2.728144354,-1459.2335383277386 -3632,3632,A215F,0.011324236000000001,0.040074227000000004,0.019395251000000002,-1.433333779,-1.90507016,-0.038972507999999996,0.129905689,-0.107257218,-0.049421677000000004,0.09966261,-0.019514157,0.082018933,-0.043228431,-1.8356735830000002,-1.030993975,-2.184980359,-1.62515996,0.6966364820000001,0.6785079959999999,-15.70080672,-15.17814287,-17.85481683,-15.74475196,-16.02049361,-13.70582833,-6.476577239,-2.007364541,-1465.5665122088976 -3633,3633,A215I,-0.066446244,-0.041434982999999995,-0.041298302,-2.2483158,-1.728916565,0.011638128000000001,-0.054484942,-0.078407546,0.02914688,-0.07536680400000001,-0.0075031609999999995,-0.063925507,-0.018671097,-2.05416869,-2.44246291,-1.8014154759999998,-1.656417654,0.741039514,0.648722835,-11.90453562,-12.38342065,-13.84775199,-9.127097649,-12.03987695,-12.12453085,-7.139822205,-3.3889831960000003,-1451.4966729385778 -3634,3634,A215H,0.058867624,0.086784989,0.059561607999999995,-0.31565459,-1.550710905,-0.103826555,0.05734369,0.060391558,0.02464171,0.077364732,0.096205246,0.12736731699999998,-0.008244102,-0.212239683,-0.41906949600000004,-2.041073784,-1.060348026,1.126547155,1.310877743,-13.65726951,-13.22027788,-14.31032695,-13.23880022,-12.87348872,-14.64345377,-6.508266357,-2.214085071,-1449.3620380768552 -3635,3635,A215K,-0.07237293,0.018382935,0.019289136999999998,-0.232453701,-1.870409311,-0.156284342,0.013972439,-0.158718298,-0.070237752,0.014033608000000001,0.022732262000000003,0.175299085,-0.136720812,-0.170822762,-0.294084639,-2.122189529,-1.618629093,0.9896520870000001,1.299190247,-10.60752401,-11.37804474,-11.92988868,-9.31729174,-10.40679529,-10.00559961,-6.466888514,-2.477148377,-1440.7624843115918 -3636,3636,A215M,-0.08389416599999999,-0.059637207000000005,0.15463194800000002,-1.654397572,-1.50909235,-0.001800405,-0.053553797,-0.114234535,-0.037445239,0.15087156699999998,-0.27014598100000003,0.255705422,0.053558472999999995,-1.7728827530000002,-1.5359123909999999,-2.122189529,-0.89599517,0.46910384,0.6758235990000001,-12.01662661,-12.93240746,-14.94960044,-10.273307899999999,-12.26865303,-9.659164207,-7.460159527,-3.673600615,-1453.9558638939634 -3637,3637,A215L,-0.07608236,-0.026271226,-0.10827483800000001,-1.715166763,-2.504267698,0.070147608,-0.046537164000000006,-0.105627556,-0.044833172000000004,-0.024749331,-0.02779312,-0.10037525900000001,-0.11617441699999999,-1.66785485,-1.762478676,-2.9714041360000003,-2.03713126,1.0043461009999999,0.711978474,-13.96884615,-13.66697993,-17.44785216,-11.05689151,-14.45274866,-13.21975848,-7.647401964,-3.853275579,-1453.4265804695897 -3638,3638,A215N,-0.109294524,-0.093327624,-0.06071278099999999,-0.254367584,-1.684866444,-0.09329905699999999,-0.055975707,-0.162613341,-0.055174006,-0.12979047300000002,-0.056864775,0.071303468,-0.192729029,-0.148315421,-0.36041974600000004,-1.48786236,-1.881870528,1.087760286,1.35943796,-10.59041736,-10.82385738,-11.98496444,-10.14614839,-8.913172142,-11.08394446,-5.1454684969999995,-0.7952781059999999,-1448.9220976252109 -3639,3639,A215Q,0.047340227,-0.016899200000000003,-0.006710984000000001,-0.314523183,-2.01652056,-0.084776385,0.063424225,0.031256228,-0.07783799,-0.02274379,-0.01105461,-0.02375454,0.010332573000000001,-0.368312165,-0.2607342,-2.2361328819999997,-1.796908238,1.46450957,1.298843281,-10.94861969,-11.13708069,-11.75186317,-10.73216604,-10.39005102,-10.73193754,-6.135161753999999,-2.579041529,-1446.8466669670306 -3640,3640,A215P,-0.016448781000000003,0.043188129000000006,0.044296746,-0.402080592,-1.5563334,-0.105342384,0.011024903,-0.043922464,-0.041923683999999996,0.028240769,0.058135488,0.11310813800000001,-0.024514647,-0.34427861299999996,-0.459882571,-1.799528355,-1.313138445,1.450491059,1.382997745,-10.82438518,-11.11246517,-11.72284933,-10.33510964,-10.10185222,-10.84964953,-7.43306654,-3.673600617,-1438.067292671185 -3641,3641,A215S,0.019278083,0.014809262,0.075964766,0.073168095,-0.430107826,-0.10242640900000001,0.061736669,-0.023180503999999998,-0.028347981,0.07728183,-0.047663307,0.147774242,0.00415529,0.10158317900000001,0.04475301,-0.55778291,-0.302432741,0.471449348,1.377525086,-5.247889478,-5.622802322,-5.6264218370000005,-5.8872985,-4.520085388,-4.58283934,-3.983585836,0.407801727,-1454.6617604396306 -3642,3642,A215R,-0.009886063,-0.035762112,0.036737023,-0.39130344200000006,-1.642443334,-0.099139037,0.000167614,-0.01993974,-0.009045876999999999,0.00727928,-0.07880350400000001,0.119521445,-0.046047399,-0.331798869,-0.450808015,-1.858948095,-1.425938572,1.427829104,1.36357387,-12.20885485,-12.51672195,-12.92003445,-11.36292719,-10.84275133,-13.40183932,-6.441073371,-1.583870406,-1436.344337511342 -3643,3643,A215T,-0.007732291999999999,-0.017173671,0.049608933,0.036441615,-1.243536899,0.081948903,0.05735765599999999,-0.072822239,-0.033854659,0.013873085,-0.048220427,0.135876805,-0.03665894,0.067512689,0.00537054,-1.4241835530000002,-1.062890245,0.485960664,1.313179273,-4.921768552,-5.408876144,-5.351601028,-5.982999657000001,-4.379944298,-3.4854216310000004,-3.806535484,-0.906021656,-1445.4192174999043 -3644,3644,A215W,-0.141502671,-0.10599767,-0.37146928100000004,-1.896191995,-1.844041984,0.04633253,-0.091339664,-0.19166567699999998,-0.11644366199999999,-0.0020958929999999997,-0.209899447,-0.281158969,-0.461779593,-2.402971468,-1.389412521,-2.7522782439999998,-0.9358057240000001,0.927137957,0.446977464,-15.14971063,-14.23621075,-16.65526324,-14.77770676,-13.62365913,-16.45571325,-6.245466459,0.253314258,-1469.9700517165475 -3645,3645,A215V,0.025584387000000004,0.012245352,0.09173098699999999,-0.806085664,-1.7898338569999999,-0.030929356,0.069006949,-0.017838176,-0.020486978,0.024569802999999998,-7.91e-05,0.15498900599999998,0.028472967999999998,-0.7872805740000001,-0.8248907529999999,-1.784947361,-1.794720352,2.065604958,1.5792932519999998,-9.204069029,-10.4230806,-10.54235567,-7.129606658999999,-9.45711795,-8.468184265,-6.91527874,-3.620203055,-1450.2668665912934 -3646,3646,A215Y,-0.017559171999999998,-0.053796610999999994,0.060525632999999995,-0.938298511,-2.06100181,-0.136957918,0.040844585,-0.075962929,0.007381498,0.008281279,-0.11587449999999999,0.12623600199999999,-0.005184737,-0.8865404790000001,-0.990056543,-2.349790608,-1.7722130109999998,0.8328326890000001,0.78501274,-16.700724599999997,-15.35069089,-17.99366364,-17.34643345,-15.98576097,-16.82707406,-6.8414549739999995,-1.49115889,-1454.6541792633943 -3647,3647,G216A,-0.0028913890000000003,-0.006613634,0.000318167,-0.01109758,-0.310987193,-0.038288444,-0.032719569,0.026936792,-0.025029696,0.010363698000000001,-0.023590965,0.023572599,-0.022936265,0.016845493,-0.039040653,-0.24666417,-0.375310215,1.228768595,1.90874274,-4.123762885,-3.940602737,-3.436713722,-3.426140205,-5.930458351,-3.884899406,-4.275803052,0.067327612,-1460.1935554505326 -3648,3648,G216C,-0.011777837,-0.08825125199999999,-0.006519942,0.013217701,-1.719736905,-0.09907958,-0.05279452900000001,0.029238856,0.041375562000000005,0.011062221,-0.187564725,-0.005469315,-0.007570569,0.026200743,0.00023465900000000002,-1.43248083,-2.00699298,0.569565963,1.315662319,-9.829597905,-11.20352809,-10.80347881,-8.38556945,-11.43682791,-7.318585258,-7.799637959,-3.8818279760000003,-1457.9081521774642 -3649,3649,G216E,-0.023045445,-0.036870406,-0.115991916,-0.024259738,-1.070069416,-0.13970165,-0.065499025,0.019408136,-0.148698421,-0.008425086,-0.065315725,-0.19403489999999998,-0.037948931,-0.038235865,-0.010283611,-0.951825114,-1.188313717,1.0615992429999999,1.43270767,-5.958552121,-6.413950066,-7.316737862,-5.349125526,-4.8617041930000005,-5.851242957999999,-5.4299773579999995,-0.7910148090000001,-1459.4448321275413 -3650,3650,G216D,0.0064812690000000004,-0.020265753,-0.031938171,-0.068140823,-1.1015153979999999,-0.05232578400000001,-0.001308344,0.014270882,-0.027285776,-0.013603513000000001,-0.026927992,0.0032921559999999996,-0.067168498,-0.084767056,-0.05151459,-1.155964158,-1.047066638,1.02220432,1.38932045,-2.761740132,-2.667551071,-5.886782516,-2.29176622,-1.8314968409999999,-1.131104012,-2.536583793,1.03013546,-1464.0404303362593 -3651,3651,G216F,0.127374983,0.057259415,0.035869193,0.108238986,-1.497825789,-0.081839521,0.139418061,0.115331905,0.05605143,0.016685635,0.097833195,0.054808714,0.016929671,0.068867079,0.147610892,-1.311081595,-1.684569982,0.574924068,1.3230950879999999,-9.735053555,-10.67012408,-10.90055251,-7.286821892000001,-13.1344863,-6.683282997,-6.430951117999999,-3.5793459739999998,-1462.4409996587783 -3652,3652,G216I,0.005978926999999999,0.019712228999999998,0.024611876,-0.011751026999999999,-1.730204233,-0.035276787000000004,-0.022130087000000003,0.034087941000000004,-0.034125199999999994,-0.07234532099999999,0.111769779,-0.015229153,0.064452905,-0.012845226000000001,-0.010656828,-1.394692269,-2.065716196,0.602068069,1.319526861,-9.899021825,-10.94562433,-9.961905052,-8.179973145,-12.38141537,-8.026191223,-6.683863313,-3.23999094,-1461.6274457317777 -3653,3653,G216H,0.005670523,-0.035751846000000004,-0.022058478,-0.026433043,-0.843535431,-0.056283924000000006,-0.00881639,0.020157436,-0.0060057059999999995,-0.013061298,-0.058442392999999995,-0.011470922,-0.032646034,0.0034251520000000003,-0.056291238,-0.766524205,-0.920546657,0.763675241,1.39781194,-7.512663794,-9.715436852,-8.846412231,-5.664222801,-6.513981887999999,-6.823265198,-6.742360305,-1.530177956,-1452.9582288824022 -3654,3654,G216K,-0.083295625,0.021156261000000003,-0.06517661200000001,0.020580031999999998,-0.637357076,-0.10686667300000001,-0.132387739,-0.034203511,0.187723549,-0.0061226580000000004,0.04843518,0.007167079,-0.13752030199999998,0.034882581,0.006277481999999999,-0.46360385299999995,-0.811110298,0.81836707,1.4904648669999998,-5.536546777000001,-7.198613495,-4.545164421,-5.202698227,-5.436162453,-5.300095291,-5.125700086,-0.144154606,-1457.5972451502457 -3655,3655,G216M,-0.088814743,-0.169258512,0.014768267,0.043411705,-0.525735054,0.025537795,-0.10936280300000001,-0.068266683,0.10271276,0.026526262999999998,-0.36504328700000005,0.05120459,-0.021668057,0.08133732099999999,0.005486089,-0.309142236,-0.742327871,1.2462143159999999,1.8597983809999998,-8.505143003999999,-8.082379524,-8.747419228,-6.966036118,-10.62299767,-8.106882484,-6.461383478999999,-2.624256006,-1459.7889716415666 -3656,3656,G216L,0.006812556,-0.069455419,-0.009667596,-0.017054918999999998,-0.765563344,-0.060545044000000006,-0.018732923999999998,0.032358035,-0.032882583,-0.009582239000000001,-0.12932859800000002,0.017036847,-0.036372037999999995,-0.012574591999999999,-0.021535245,-0.640059523,-0.891067165,0.8851020059999999,1.456194861,-7.2345199860000005,-7.648190102,-8.041867706,-6.513365547,-9.087525932,-4.881650642,-5.298610443,-0.927385833,-1456.3990933476016 -3657,3657,G216N,-0.055483692,0.061163385,-0.09118140300000001,-0.032140943,-0.17146729800000002,-0.01175052,-0.017639547,-0.093327836,0.038425467000000005,-0.074356724,0.19668349300000001,-0.08349398400000001,-0.098868822,-0.078667118,0.014385233,-0.15560012199999998,-0.187334473,1.427809532,2.213852115,-4.98125697,-6.371647972000001,-5.608445777999999,-4.266888374,-5.389413246,-3.2698894810000003,-4.49872886,0.217256034,-1456.1636538198218 -3658,3658,G216Q,0.06856371,-0.036985715,-0.0009493860000000001,0.03091792,-0.160168266,0.035652674,0.050177399000000004,0.08695002,-0.106675867,-0.035959431,-0.038011999,-0.015933351000000002,0.014034578999999998,0.028942213999999997,0.032893626,-0.190146979,-0.130189553,1.345179325,2.138992574,-5.3637503539999996,-5.180051253999999,-6.1174476779999996,-4.2504535830000005,-5.4810293660000005,-5.78976989,-5.162203505,-0.943110285,-1464.0169323529117 -3659,3659,G216P,0.018835202,0.016392633,-0.012354637,-0.116471786,-1.499187483,-0.105826945,-0.00729243,0.044962833,0.001844382,-0.01607658,0.048861845,-0.024294195,-0.00041507800000000004,-0.08077118,-0.152172392,-1.7481523330000002,-1.250222633,0.858667251,1.316704003,-8.806176485,-7.7755283429999995,-7.824593826,-7.082954658999999,-13.36670285,-7.981102745,-5.359209936,-0.057788978,-1450.3304046802223 -3660,3660,G216S,0.012239866,0.046390495999999996,-0.006090613000000001,0.007996046,-0.7025688729999999,-0.07796723,0.008922055,0.015557676000000001,-0.011791515,0.006466469,0.086314523,-0.017038311,0.004857085,0.00257987,0.013412221,-0.619317663,-0.785820083,0.935288536,1.4824072480000001,-5.430268887,-6.125199554,-5.420694496,-3.9049039839999997,-7.252644257,-4.447902145,-5.0560766930000005,-1.14001398,-1455.8653624989092 -3661,3661,G216R,0.018601533,-0.084044105,-0.018486798999999998,0.001997235,-0.9179424359999999,-0.053407795,-0.022573445,0.059776511,-0.012876648000000001,-0.0072348080000000006,-0.16085340199999998,-0.017980875,-0.018992723,-0.00842136,0.01241583,-0.759927791,-1.0759570809999999,0.920282128,1.440236012,-5.578184041,-6.22638884,-5.660751128999999,-5.247268707,-4.796957878,-5.95955365,-4.165581816,0.35492957299999994,-1455.6264411117882 -3662,3662,G216T,-0.017409265,0.01468483,-0.029651074,0.0058366569999999994,-0.6573795139999999,-0.082856638,-0.016353305,-0.018465224,-0.024851656,0.011719896,0.017649763,-0.022211206,-0.037090941,0.041773459,-0.030100146,-0.5882838229999999,-0.726475205,0.502090185,1.377211586,-6.122869049,-6.512450737000001,-5.951319,-4.670941513,-8.399427589,-5.080206406,-4.719979186000001,-0.307093202,-1456.831366814673 -3663,3663,G216W,-0.054449038,-0.063948116,-0.046229828,-0.060131902,-0.921568061,-0.051959856,-0.072343248,-0.036554827000000005,0.10057337400000001,-0.049306752,-0.078589479,-0.01748621,-0.074973446,-0.041762574,-0.07850123,-0.697979322,-1.1451568,0.844221632,1.430358798,-11.01124455,-12.18530641,-10.73918853,-8.987266579,-13.41910608,-9.725355171,-7.578798344,-2.718290917,-1461.6301759649068 -3664,3664,G216V,-0.026932497000000003,-0.122627764,-0.037714492999999995,-0.008556777,-1.553889303,-0.10530362,-0.082514931,0.028649937,0.009468925999999999,0.016861991,-0.262117518,-0.013586282,-0.061842704000000005,0.043027867000000004,-0.060141420999999994,-1.57385276,-1.533925845,1.0812690120000001,1.352034995,-8.211486241,-9.392539841,-8.385290741,-6.367401382000001,-10.45328177,-6.458917473,-5.611465905,-1.929282358,-1461.962414578069 -3665,3665,G216Y,0.02549871,0.047522568,0.0019462129999999998,-0.032947085,-1.2191909140000001,-0.100783052,0.005091310999999999,0.045906108,-0.00112494,0.003353234,0.09169190099999999,0.008737766,-0.00484534,-0.06392529799999999,-0.001968872,-1.345843701,-1.092538127,0.918759923,1.3504608009999999,-10.12734793,-12.94919798,-11.99416805,-7.097282097000001,-11.83584721,-6.760244347,-6.549859934,-2.9263482639999996,-1454.0544749596156 -3666,3666,P217A,-0.035104257,-0.016601721,-0.017223525,-0.0034384059999999998,-0.049668195,0.096735715,-0.021249645,-0.048958867999999996,0.0074137180000000006,0.037359775,-0.070563217,0.035803087000000004,-0.070250137,0.026097961,-0.032974773,-0.041158396,-0.058177994000000004,1.265315663,2.4962177690000003,-2.509097375,-1.322061172,-3.2529039460000004,-2.847630005,-2.675889229,-2.447002525,-3.9225392880000003,1.429935895,-1456.3815498952754 -3667,3667,P217C,-0.03297198,0.013342314,0.055138155999999994,0.01055482,-0.9434368390000001,-0.010828974,-0.054952272,-0.010991687,0.014776965,0.053212812000000005,-0.026528185,0.12290643,-0.012630118000000001,0.044197337,-0.023087697,-0.792481887,-1.09439179,0.6859697920000001,1.3773619540000002,-9.18079593,-8.099236937999999,-9.852977585,-9.715291191,-10.13222026,-8.104253677,-8.335996678999999,-2.626039084,-1449.735524520278 -3668,3668,P217E,0.06100943599999999,0.012347592,0.054936907,0.0027713629999999998,-0.29422413399999997,-0.079384828,0.014580248,0.10743862300000001,-0.053512758,0.054661855999999995,-0.029966672000000003,0.062797928,0.047075886,-0.008081664,0.013624388999999999,-0.160516883,-0.42793138399999997,1.332849414,2.129928596,-4.446299245,-2.9921253660000002,-5.265222672,-6.406227058,-3.8163946,-3.7515265269999998,-4.444484508,1.1872475120000001,-1454.2563465368003 -3669,3669,P217D,-0.02491113,0.078210747,0.021723402000000003,-0.004205715,-0.149352214,-0.107600285,-0.05954381,0.00972155,0.06153162400000001,0.08794054,0.06848095400000001,0.083625885,-0.040179082000000005,0.056678595,-0.06509002400000001,-0.100276332,-0.19842809600000003,1.420615056,2.563955177,-3.31890733,-1.6444342730000001,-4.038151077,-6.087297119,-3.242029198,-1.582624985,-3.558855804,1.6749039940000001,-1451.1772087546997 -3670,3670,P217G,0.013693307,-0.044341877,-0.015918068,-0.007137341,-0.494440349,-0.021776674,0.010901204,0.016485409,0.045176263,0.003845163,-0.092528916,-0.000115875,-0.03172026,-0.006212095,-0.008062586,-0.366362474,-0.6225182229999999,1.061542465,1.65479138,-3.770486748,-2.233006462,-4.8862147369999995,-5.027651802,-4.401579315,-2.3039814219999997,-5.22758833,0.579268462,-1451.6079168366268 -3671,3671,P217F,-0.052804572,-0.045092675,-0.065338427,-0.054681412,-1.509183144,-0.00678853,-0.06963878,-0.035970364,-0.057063154000000005,-0.06341561,-0.026769739,-0.077993005,-0.052683848,-0.044978834,-0.064383989,-0.941737365,-2.076628922,0.929104963,1.40094192,-10.6266267,-10.06115308,-11.17402383,-10.56356091,-11.85814646,-9.476249237000001,-8.004255367,-3.06238992,-1444.5853819600306 -3672,3672,P217I,-0.013264945,0.087849096,-0.018662892,-0.020307091,-1.350092088,-0.03216553,0.015358526,-0.041888415,0.06901248,0.109670733,0.066027458,-0.054743068,0.017417283999999998,-0.024011032999999998,-0.016603148999999998,-1.119493653,-1.5806905230000001,0.7247316770000001,1.347417956,-10.67070695,-9.136974487,-13.18514881,-10.87821847,-10.57610178,-9.577091225,-8.59648343,-3.85100613,-1446.7006292901933 -3673,3673,P217H,0.044303155,-0.02325768,0.020875202,0.004635463,-0.221030842,0.03661518,0.043755385,0.044850924,0.031148996,0.018377956,-0.064893315,0.025157897999999998,0.016592505,-0.015666664,0.024937589,-0.212436347,-0.229625336,1.557634929,2.226564484,-6.402804721,-5.672334915,-7.255904861,-7.187190384,-6.970301482999999,-4.928291962,-5.32369567,1.1257424790000001,-1451.189996568486 -3674,3674,P217K,0.062003447,0.08493882,0.020864521,0.061836518,-0.007076838,0.08753975800000001,0.09303560300000001,0.03097129,-0.005324185,0.084030467,0.08584717300000001,0.038888088,0.002840953,0.127049771,-0.003376736,-0.008684155,-0.00546952,1.321668002,2.76236175,-4.2120651989999995,-2.7358317110000003,-5.878951133999999,-4.491291534,-4.05868399,-3.8955676269999997,-4.407592617,1.256034733,-1455.844449272845 -3675,3675,P217M,-0.096982015,-0.054837605,-0.009540184,-0.11107656199999999,-0.156304504,0.054080464,-0.114283146,-0.07968088400000001,0.0075544769999999995,-0.012247672,-0.097427537,0.09955343400000001,-0.118633801,-0.020604783999999998,-0.201548339,-0.010420327,-0.30218868,1.543610422,3.106887046,-8.48229604,-7.2003639139999995,-10.06263823,-9.163198906,-8.02516124,-7.960117912,-6.955173967,-2.414323691,-1449.7725987709127 -3676,3676,P217L,-0.02001265,-0.025505335,-0.012217700000000001,-0.0067684830000000005,-0.541115992,0.034532629,-0.017922259,-0.02210304,-0.000425804,0.02809577,-0.079106439,-0.000674998,-0.023760402000000003,0.000694407,-0.014231373,-0.42074051799999995,-0.661491465,0.939392255,1.563063857,-8.280118896,-7.175396156000001,-9.614958923,-8.850492302000001,-8.040279785,-7.719467316,-7.12814073,-1.350654129,-1445.9545769584365 -3677,3677,P217N,-0.07331183,0.020165346,-0.060433929000000004,-0.031556496,-0.131099892,-0.06999781599999999,-0.019660865,-0.126962794,0.034250374,-0.01054891,0.050879602,0.018582622,-0.13945048,0.020972354,-0.084085345,-0.132451922,-0.129747861,1.347976698,2.242472497,-3.286205981,-1.9394795759999999,-3.857469818,-3.670100899,-4.168489319,-2.795490295,-4.199061503,1.421521764,-1453.2752344827168 -3678,3678,P217Q,-0.01108221,-0.011806348999999999,0.023728605,0.00961528,-0.143022174,0.022935068,-0.028996732,0.006832311999999999,0.022993202,0.03311488,-0.056727578,0.042060692000000004,0.005396518,0.031364849,-0.012134289,-0.07008448,-0.215959867,1.414904449,2.54082215,-4.848964154,-3.819085587,-5.977115891,-5.965240929,-4.59165657,-3.891721794,-5.274300252,0.645187404,-1455.8656686744653 -3679,3679,P217S,0.009533891999999999,-0.004407541,-0.017485182,0.039209529,-0.300363106,-0.036414128999999996,0.023960691,-0.004892908,0.000833784,0.02175942,-0.030574502000000003,-0.013075453999999999,-0.02189491,0.05563208099999999,0.022786977000000003,-0.227974003,-0.372752209,1.1757458509999998,1.9506696380000002,-3.674477931,-2.641335014,-4.164132088,-3.84758519,-4.298399139,-3.420938225,-4.906253993,1.033611012,-1456.1134227146395 -3680,3680,P217R,0.005384054,-0.064369505,-0.00927909,0.006105439,-0.5122000529999999,0.045422297,0.003550502,0.007217605,-0.00388548,0.024073706,-0.152812715,0.002552824,-0.021111003,0.01958839,-0.007377511999999999,-0.36408305700000004,-0.660317049,1.059478962,1.6624555419999998,-6.319127513,-4.357751511,-8.642395096,-8.541373199,-5.643384094,-4.410733665,-7.003257388,0.825908596,-1446.7552386531606 -3681,3681,P217T,-0.012296521999999999,0.06112032,0.010158154,0.024849086,-0.193910919,-0.016709769,0.0063608630000000005,-0.030953907000000003,0.036944433,0.06377154,0.0584691,0.03635239,-0.016036083,0.030984874,0.018713298,-0.182900399,-0.20492143899999998,1.38706504,2.1532873319999997,-5.020718037,-3.379785507,-6.733288719,-5.3987373960000005,-4.386834358,-5.204944206,-3.8798400280000003,1.272994125,-1454.4804154522717 -3682,3682,P217W,-0.002458467,-0.058029986,0.016268091000000002,-0.00227249,-1.924774941,0.01720804,0.005117292,-0.010034226,-0.048123873,0.054608137,-0.170668108,0.039542449,-0.007006268,0.042294497,-0.046839477000000004,-1.6002190319999998,-2.249330849,0.652179761,1.3160173370000001,-10.38073444,-8.452413818,-11.27014333,-11.69978212,-11.45692411,-9.024408836000001,-7.972537725,-2.626039029,-1447.1788332103752 -3683,3683,P217V,0.064024997,-0.014537332,0.032537464,0.024850381,-0.281510655,-0.009649058,0.026728988999999998,0.101321004,0.032116244,0.010234696,-0.03930936,-0.021308213,0.08638314,0.02730562,0.022395141,-0.157132265,-0.405889044,1.282950559,2.134169417,-8.920625391,-7.402179199,-11.73463029,-9.305690056,-8.63942498,-7.521202431,-7.082447889,-1.857570271,-1449.110934310127 -3684,3684,P217Y,0.047043569,0.029349611,0.034346435,-0.018649918999999997,-1.0447035359999999,-0.040709913,0.046445674000000006,0.047641462999999995,-0.046219870999999996,0.014122765,0.044576457,0.030737741000000002,0.037955128,-0.045520272,0.008220435,-0.809746545,-1.279660527,0.642309334,1.3657376509999999,-9.076290976000001,-8.287556992,-9.778807709,-9.126171005,-10.49586242,-7.693056755,-6.740915825,-0.886155062,-1441.5870272293687 -3685,3685,L218A,-0.034110833,-0.04109114,-0.034370896,-1.573596662,-2.1574896690000003,-0.074077556,-0.066592123,-0.0016295429999999998,0.004778844,-0.040118443,-0.042063837,-0.049298725999999994,-0.019443066000000002,-1.4610414669999998,-1.6861518569999998,-2.022505783,-2.292473555,2.715898052,1.784616108,-11.82753091,-11.06658401,-11.90531981,-12.95222167,-14.47699582,-8.736533218,-6.877561983,-2.870603811,-1441.2386313960887 -3686,3686,L218C,-0.08650015800000001,-0.020835752,-0.07063399,-0.9677473129999999,-1.8879856640000001,-0.030762592000000002,-0.10341442199999999,-0.06958589400000001,0.126250374,-0.045633214000000005,0.003961711,-0.068732608,-0.072535371,-0.517643752,-1.417850874,-2.071440627,-1.7045307,1.691891293,1.367684752,-11.04510899,-8.708488396,-11.26071796,-12.6633233,-13.45234252,-9.140672752,-6.760660675,-2.497484833,-1446.3422138970345 -3687,3687,L218E,-0.036320597,-0.022625097,-0.680249856,-1.780352837,-2.809141168,-0.142126885,-0.068498151,-0.004143043,0.042494168,-0.028148711,-0.017101483,-0.715149521,-0.645350191,-1.891297807,-1.6694078669999999,-2.656882106,-2.96140023,1.972674251,0.8676063629999999,-14.649134099999998,-14.14951814,-13.68281259,-16.15465314,-17.98563412,-11.27305253,-8.236131653,-2.817413684,-1441.199542561546 -3688,3688,L218D,0.023469782999999998,-0.070989311,-0.091439376,-1.788551701,-1.649850489,-0.128680764,0.034667892,0.012271674,0.106759286,-0.048510595999999996,-0.093468025,-0.083999511,-0.09887924,-1.671686814,-1.905416588,-2.0624549030000003,-1.237246074,1.0044752259999998,0.712251304,-17.48504528,-15.11093855,-20.59971222,-19.56408167,-18.87847422,-13.27201973,-8.78994063,-3.482839062,-1436.7941305749118 -3689,3689,L218G,-0.032382493,-0.04383445,-0.034613908,-1.504824648,-2.040364951,-0.11223298300000001,-0.044399197,-0.020365788,-0.017982776000000002,-0.057942888,-0.029726011,-0.05268033900000001,-0.016547476999999998,-1.396199891,-1.613449405,-2.198213455,-1.882516446,0.932425368,0.734638385,-14.007753699999999,-13.32759182,-12.2119784,-16.0877579,-17.87385423,-10.53758617,-7.04881436,-1.9398267980000001,-1432.086772378534 -3690,3690,L218F,-0.09902433,-0.047278677000000005,-0.023279547,-1.727729377,-2.233060674,-0.075599776,-0.085095553,-0.112953106,-0.03698062,-0.048462299,-0.046095054,-0.005057956,-0.041501137,-1.485065528,-1.9703932259999999,-2.301802349,-2.1643189990000002,0.952540715,0.7300441959999999,-9.634879424,-8.110473755,-10.8925898,-10.92467815,-9.719133072,-8.527522338999999,-8.101519885,-4.0820173969999995,-1450.5505288420245 -3691,3691,L218I,-0.010461264,-0.015606700000000001,-0.034513271,-0.21312514,-1.350570111,-0.053618331,0.021849952000000002,-0.042772479,-0.129267703,-0.112977494,0.081764095,-0.102610519,0.033583978,-0.168047427,-0.258202852,-1.829882288,-0.871257933,1.246472262,1.341526937,-8.733722961,-8.553791061,-7.460346213999999,-10.24869703,-9.959099205,-7.4466812970000005,-8.163864795,-2.403246097,-1453.5788729111664 -3692,3692,L218H,-0.002556199,-0.027350066,-0.169681127,-1.7178171269999998,-2.623540895,-0.075591185,0.005930673000000001,-0.011043071000000002,0.060854177,-0.05856037099999999,0.00386024,-0.225765347,-0.113596907,-1.726155729,-1.709478525,-2.412558781,-2.8345230089999998,1.2732007490000001,0.7359063770000001,-13.53327335,-11.32437807,-14.51921588,-16.22522029,-13.82624717,-11.77130534,-8.242263906,-4.099427563,-1440.2332213968039 -3693,3693,L218K,-0.039520723,0.005233643,-0.777621553,-1.821604501,-2.5606165069999998,-0.11779410400000001,-0.012516916000000001,-0.06652453,-0.108171992,-0.053374829000000006,0.063842114,-0.918312556,-0.636930549,-1.673197405,-1.970011596,-2.489934226,-2.631298787,2.628416573,1.358083519,-9.306860046,-10.09038832,-7.127389343,-9.932597824,-10.61110559,-8.772819153,-6.032343238999999,-0.432725376,-1440.4268884351477 -3694,3694,L218M,0.01391873,0.009697374,0.02547685,0.036105148,-0.36244186700000003,0.005535481,0.036833676,-0.008996216,-0.036881454,0.018470811,0.000923937,0.023573546,0.027380152999999997,0.10630188900000001,-0.034091592999999996,-0.28536443100000003,-0.43951930200000006,0.8841236729999999,1.641405735,-5.288082295,-5.626445381,-4.875713234,-5.518775101,-5.999373917000001,-4.420103844,-6.539617073,-2.159175191,-1456.8664477043785 -3695,3695,L218N,-0.034380883,-0.033071571,-0.10296307199999999,-1.79807484,-2.612333267,-0.073462162,-0.038265399,-0.030496366,0.027045407999999996,-0.09914542,0.033002279,-0.10422192699999999,-0.10170421699999999,-1.879010546,-1.717139134,-2.440474862,-2.7841916710000003,1.076361799,0.690782792,-12.96661017,-12.19876714,-10.3621698,-16.52243047,-15.24110163,-10.50858183,-8.444065399,-4.2233854619999995,-1438.5213723587804 -3696,3696,L218Q,-0.036080357,-0.063033365,-0.17492843800000002,-1.738611119,-2.130320525,-0.14672090599999998,-0.064043327,-0.008117387,0.07222351,-0.083389089,-0.04267764,-0.163658453,-0.186198422,-1.660807816,-1.816414421,-2.523302128,-1.737338922,1.1354337970000001,0.727571482,-11.516641400000001,-12.12877222,-10.07949226,-13.47332497,-12.17932923,-9.72228833,-6.399284082,-2.6555147040000002,-1447.6620783647522 -3697,3697,L218P,-0.047777103,-0.013548348,-0.008879468,-1.565164754,-2.095105062,-0.095478639,-0.060118954,-0.035435251,-0.013532196000000002,-0.024763436,-0.00233326,-0.016297318999999998,-0.001461616,-1.530617409,-1.599712099,-2.23820976,-1.952000364,1.024458581,0.731841463,-14.18916834,-13.25152785,-13.990549,-16.03448138,-16.88298299,-10.78630045,-8.577109007999999,-4.509438339,-1445.8927923999727 -3698,3698,L218S,-0.03369373,-0.009907581,-0.19106020899999998,-1.784374889,-3.0797503139999995,-0.116096276,-0.048959462,-0.018427996999999998,0.00037849,-0.05862287099999999,0.038807708999999996,-0.201259656,-0.18086076199999998,-1.687409599,-1.881340178,-2.819416854,-3.340083773,1.21515909,0.732844825,-10.80714834,-10.73514618,-8.804790703,-13.09964452,-13.14909433,-8.247065994,-6.8253776770000005,-1.702308556,-1438.1880465140566 -3699,3699,L218R,-0.032774274,0.007219869,-0.9862792420000001,-2.20290449,-2.751810874,-0.058135224000000006,-0.039314664,-0.026233884,-0.004905424,-0.020281338,0.034721075,-1.021127935,-0.9514305479999999,-2.223170816,-2.182638163,-2.562786382,-2.9408353660000004,0.8003237990000001,0.13086038,-8.827390225,-8.142323524,-6.8725079120000006,-10.28778353,-9.699333244,-9.135002914,-5.410978428,1.0774628309999998,-1446.8578249304555 -3700,3700,L218T,0.014576708999999998,0.004411020999999999,-0.006654996,-1.54755897,-2.242838135,-0.132305396,-0.041012009,0.070165426,-0.056035789,0.000589628,0.008232413000000001,-0.029985551000000003,0.01667556,-1.426673574,-1.668444366,-2.445515087,-2.040161183,0.618889537,0.7050145329999999,-8.521758916,-7.709965286,-7.067710114,-9.833602615,-12.13737011,-5.860146454,-6.582300276000001,-2.163665871,-1447.7930627707392 -3701,3701,L218W,0.000904237,0.039769528,-0.687777765,-1.865651239,-2.414557624,-0.11449863099999999,-0.029071924,0.030880397999999996,0.028070915,0.046746039,0.032793017,-0.7544871679999999,-0.6210683610000001,-1.764644523,-1.966657954,-2.5022000980000003,-2.326915149,2.105316931,0.987067598,-11.69260705,-10.13171888,-12.73180041,-14.46376572,-9.942488617,-11.19326164,-8.169695392000001,-2.92512573,-1448.2331949309446 -3702,3702,L218V,-0.002427662,-0.041385094,-0.004195211,-0.9559772040000001,-2.045548314,-0.09399794,-0.023520269,0.018664945,0.01769726,-0.076660256,-0.006109931,-0.05601664,0.047626219000000004,-0.650411737,-1.261542671,-2.040301576,-2.050795052,1.855945807,1.4132685440000001,-8.662192828,-7.526389,-7.015631217999999,-11.31917018,-10.86951732,-6.580256424,-7.282305222000001,-2.482387337,-1451.1062644310296 -3703,3703,L218Y,-0.010062209,0.063228564,-0.49222118600000003,-1.8373467,-2.606993534,-0.066623058,-0.015345484,-0.004778934,-0.001323456,0.026582636,0.099874492,-0.378843765,-0.605598606,-1.804869525,-1.8698238740000002,-2.445515087,-2.76847198,1.500276084,0.761652785,-12.54110254,-9.321149979,-14.70205543,-14.84520763,-12.14179208,-11.69530758,-7.377820467,-2.578954384,-1443.0903082261793 -3704,3704,L219A,0.025114333,-0.008984792,-0.018802827,-1.538832679,-1.9655427090000002,-0.036415291,0.02520131,0.025027356,-0.023270697000000003,0.00562387,-0.023593452999999997,-0.077657844,0.040052191,-1.5282194759999999,-1.549445881,-2.270002019,-1.6610833980000002,0.834185235,0.7116021709999999,-8.009758572,-8.677106422,-8.326057837999999,-8.424227821,-6.589509422000001,-8.031891357000001,-5.638754157,-3.088819925,-1449.779644886963 -3705,3705,L219C,-0.006903001,-0.015711658,0.028391857000000003,-1.638408679,-2.7274145780000003,-0.072491812,0.004820308,-0.018626309,0.011960538,-0.01051578,-0.020907535,0.015878928,0.040904786,-1.5850553230000002,-1.691762035,-2.8149545039999997,-2.639874652,0.149696623,0.6805364759999999,-10.54020282,-11.13402138,-10.37099089,-11.03966244,-10.07617941,-10.080160000000001,-8.973277603,-9.972551682,-1459.7692316952161 -3706,3706,L219E,0.07766340599999999,0.012207131000000001,0.06259669,-1.638387124,-2.438363166,-0.006254776,0.076460533,0.078866279,0.013357341000000002,-0.020126717,0.044540979,0.001250469,0.123942911,-1.789854421,-1.4869198259999998,-2.292754875,-2.583971457,0.64276054,0.679151458,-11.66728859,-12.15368471,-11.47877463,-12.14192462,-11.10679507,-11.45526392,-9.016060319,-10.11260904,-1452.9650259991176 -3707,3707,L219D,0.070535704,0.060995399000000006,0.056442419,-0.9833529320000001,-2.447858334,-0.066191186,0.049082485,0.09198892199999999,0.050061317,0.080793431,0.041197367,-0.004992255,0.11787709199999999,-0.87992501,-1.086780853,-2.711884183,-2.183832484,0.6874554979999999,0.761446911,-12.01517683,-12.16334091,-12.48077892,-12.48298676,-11.48049861,-11.46827892,-9.016060319,-10.11260885,-1458.8073051478714 -3708,3708,L219G,0.004724535,0.011219492,-0.255226823,-1.669207766,-2.710439912,-0.006162322,0.007365132,0.002083938,-0.011992107,-0.008269571,0.030708554,-0.332197972,-0.17825567399999998,-1.6363959559999999,-1.702019575,-2.692664476,-2.728215348,1.530181225,0.807469765,-10.81862116,-11.05822324,-11.30454337,-11.34955824,-10.05514713,-10.32563382,-7.064636384,-5.079969338,-1456.3913244628347 -3709,3709,L219F,-0.038369486,-0.225249692,0.021873568,-0.00622174,-0.542806621,-0.107124913,-0.06171225,-0.015026722,0.06379011799999999,-0.024716754,-0.42578262899999997,0.019894568,0.023852567,-0.017452874,0.005009395,-0.382050629,-0.703562612,0.6650736620000001,1.473064635,-2.997163843,-3.777477005,-2.770237419,-3.33406266,-2.9047666239999996,-2.199275505,-2.695602487,-2.251337595,-1454.4941940666176 -3710,3710,L219I,0.18619180600000002,-0.300584627,0.077223272,0.050990682999999995,-0.34198399799999996,-0.006621487,0.103516173,0.268867438,-0.007053638,-0.042073852,-0.559095401,0.0008089060000000001,0.153637637,0.020273711,0.081707654,-0.016450487,-0.667517508,1.281800064,2.6320161069999997,-1.586831035,-2.1630085980000002,-1.9536074140000002,-1.644639015,-1.068472404,-1.104427742,-1.783438242,-0.18402698899999997,-1466.917176705785 -3711,3711,L219H,0.015948308,-0.04401112099999999,0.013208633000000001,-1.613842953,-2.192562432,-0.007528433,0.03084621,0.001050405,7.32e-05,-0.020753857,-0.067268384,-0.040132671,0.066549937,-1.6191581940000002,-1.6085277119999999,-2.3439073969999997,-2.041217466,0.708491084,0.6984635029999999,-10.88346806,-11.94007615,-10.4305128,-10.91085563,-10.43862392,-10.69727181,-9.016060319,-10.1126085,-1455.4636737434193 -3712,3712,L219K,-0.000560749,0.036116381,-0.010258716999999999,-1.589377857,-2.040645811,-0.047319220999999995,-0.030744197,0.029622700000000002,0.033994662,0.021968932000000004,0.050263829,-0.031448619,0.010931185,-1.4922041659999998,-1.6865515469999999,-2.421073352,-1.660218269,0.947622538,0.725118061,-11.50395784,-11.92727293,-11.41548264,-11.83239072,-10.68977407,-11.65486882,-9.016060319,-10.11260934,-1454.64831288578 -3713,3713,L219M,-0.055092916,0.09125686300000001,0.004683021,-0.03230548,-0.595117345,-0.052413139000000004,-0.075580596,-0.034605236,0.003610038,0.025390306,0.15712342,0.01034455,-0.0009785080000000001,-0.053000939000000004,-0.011610021000000002,-0.41156672899999996,-0.77866796,1.1186367190000002,1.671303432,-4.106352252,-4.575011856000001,-3.6470669630000003,-5.772195839,-3.147541168,-3.389945435,-5.088416564,-2.674381237,-1454.9765039491467 -3714,3714,L219N,-0.026094242,-0.008409513,0.000884204,-1.480173015,-2.58579938,-0.11456295,-0.02842621,-0.023762274,0.00857715,-0.040091615,0.02327259,-0.09451642199999999,0.096284829,-1.3665915830000002,-1.593754446,-2.693400777,-2.4781979830000003,0.998709805,0.747776584,-11.43184657,-12.04677184,-11.40608025,-11.70255564,-10.77312357,-11.23070152,-9.016060319,-10.11260922,-1456.4186384337954 -3715,3715,L219Q,-0.008193556,-0.031420794,0.013768855,-1.5956992069999998,-2.141130018,0.011933808999999998,0.023340042999999998,-0.039727155,0.046714232,0.013327199,-0.076168787,-0.04167621,0.069213919,-1.477364804,-1.7140336090000001,-2.059446503,-2.222813532,0.79896248,0.7181723790000001,-11.29410985,-11.58817986,-11.34909618,-11.81362836,-10.32032532,-11.39931953,-9.016060319,-10.11260922,-1450.4284163154662 -3716,3716,L219P,0.013242688,-0.004430684,0.006998325,-0.75809352,-1.8484508530000001,-0.049241707,0.03929659,-0.012811214,-0.017842373999999998,-0.022713587,0.013852218999999999,-0.058634612999999995,0.072631263,-0.631824354,-0.8843626859999999,-2.007276727,-1.689624978,1.803454184,1.407668247,-11.31121702,-11.93466834,-11.253411900000001,-11.67540392,-10.7752403,-10.91736063,-8.415656587,-8.087553656,-1451.8462824271992 -3717,3717,L219S,0.043221262,-0.039701381,-0.028592395,-1.4824147769999998,-2.416982134,-0.058391140999999994,0.019563272,0.066879251,0.018400003,-0.006360436,-0.073042325,-0.073626212,0.016441423,-1.382934215,-1.5818953390000001,-2.3311085559999998,-2.502855711,0.668121338,0.710430695,-8.50593278,-9.749859116,-7.973522919,-8.901148376,-7.330169579,-8.574963913,-6.286328004,-4.423684472,-1453.9576334063895 -3718,3718,L219R,0.005178914000000001,-0.0056466630000000005,-0.002784307,-1.527060225,-2.207771293,-0.033938708,0.026285284,-0.015927457,-0.008137551,-0.051792030999999995,0.040498705,-0.094909626,0.08934101300000001,-1.540659265,-1.513461184,-2.312990728,-2.102551858,1.003961743,0.728026602,-12.00641646,-12.04749477,-12.39005212,-12.37266973,-10.99386008,-12.22800562,-9.016060319,-10.11260937,-1453.6315103862435 -3719,3719,L219T,-0.012405283999999999,-0.005184318,-0.006395438000000001,-1.7066939140000001,-2.383980324,-0.044723892,0.026711078,-0.051521645,-0.015167296,-0.035875131,0.025506496,-0.07840071400000001,0.065609838,-1.6176476030000002,-1.795740224,-2.400388753,-2.367571894,0.797848496,0.7031310340000001,-9.196696576,-9.462819077,-9.274487846,-10.28830209,-7.983264557,-8.974609306,-6.751724866,-5.5816525079999995,-1447.4223430189304 -3720,3720,L219W,0.002160145,0.034672722,0.056318645,-1.555166321,-2.493348556,-0.10835258099999999,0.020354569,-0.01603428,0.015167092,-0.001160721,0.07050616400000001,0.030186677000000002,0.08245061299999999,-1.4444931909999998,-1.6658394509999999,-2.146965999,-2.839731112,0.63465847,0.704948481,-10.10031437,-10.6553564,-9.915016143999999,-10.63860181,-9.731742073,-9.560855408,-9.016060319,-10.112609599999999,-1465.4899301566184 -3721,3721,L219V,0.028720486,0.006954276,0.003082763,-0.016339212,-0.22787344199999998,0.01576461,0.049244077000000004,0.008196894,0.001345826,-0.034856385,0.048764937,-0.07142853,0.077594056,-0.018436553999999997,-0.014241868999999999,-0.213467587,-0.242279296,1.452381735,2.093390515,-4.535940295,-4.432747101,-5.0720647660000004,-4.378806267,-3.875861496,-4.920221848,-4.52149629,-2.536753793,-1458.2863450134173 -3722,3722,L219Y,0.059062579000000004,-0.289654768,-0.226921464,-2.084155787,-2.240510973,-0.056944697,0.002024261,0.116100896,-0.07191303,0.01834096,-0.597650496,-0.33592936,-0.11791356800000001,-2.011024055,-2.157287518,-2.1159845,-2.365037446,1.395104458,0.70019404,-7.808930042999999,-9.048284973,-7.2053722989999995,-7.732498328999999,-7.603923355,-7.454571259,-7.182748421,-6.757518222000001,-1451.4096593875438 -3723,3723,R220A,-0.09285731,0.014737218,-0.037112376,-1.004084057,-2.198580773,-0.013844038000000001,-0.066982252,-0.118732368,-0.055237692000000005,-0.0053727340000000005,0.034847169,-0.040259943,-0.033964809,-0.760250072,-1.247918042,-2.09094906,-2.3062124859999997,1.943661475,1.4172691309999998,-10.02796299,-9.529456985,-8.54125238,-11.87333527,-8.87186245,-11.32390787,-5.208183325,-1.6121659640000001,-1445.4680133364163 -3724,3724,R220C,-0.021991661000000003,-0.044092083,-0.33931233200000005,-1.2555514490000002,-1.8430280380000001,-0.024991964,-0.0027799290000000004,-0.041203392,-0.01489921,0.02879867,-0.11698283599999999,-0.24196972100000003,-0.43665494200000005,-1.06501984,-1.4460830569999998,-1.538685226,-2.14737085,3.529698443,2.8088266589999997,-14.10118165,-13.41988519,-12.92780442,-14.92955727,-13.2756386,-15.95302277,-9.277171266,-7.078200245,-1450.372276820708 -3725,3725,R220E,0.051373450999999994,0.07172430099999999,-0.061008012,-1.7368185180000002,-2.4277697430000003,-0.021486,0.056896403,0.045850499,-0.046507304000000006,-0.022321382,0.165769983,-0.146327155,0.024311132000000003,-1.4709675309999999,-2.002669504,-2.240523273,-2.615016212,1.156099235,0.758528581,-12.92887119,-12.8564987,-11.42043869,-14.10168571,-12.88538663,-13.38034622,-7.464895001,-4.200399265,-1444.2843867056072 -3726,3726,R220D,0.10495761599999999,0.077611577,-0.238104139,-1.73191135,-2.689181867,-0.018409437,0.125500133,0.08441509800000001,-0.010944162,0.028308392,0.126914761,-0.261883032,-0.21432524600000002,-1.973515823,-1.4903068769999999,-2.839981578,-2.538382155,1.204528733,0.6844142559999999,-14.10282911,-13.35984666,-13.16314949,-14.75838268,-13.64662033,-15.58614641,-8.195634095,-5.1903931530000005,-1445.2218364952132 -3727,3727,R220G,0.032107894,0.06948671599999999,0.02790633,-1.430734526,-1.927532395,-0.081976998,0.041578397,0.022637391,-0.050108313,0.023689366,0.115284065,-0.008315852,0.064128512,-1.350300421,-1.51116863,-2.09465673,-1.76040806,2.380394008,1.533726088,-10.78065263,-10.94027393,-9.785020874,-12.03800871,-10.06550986,-11.0744498,-6.224211257,-2.940466789,-1446.1233430788852 -3728,3728,R220F,0.004401698,0.039505688,0.044299042000000004,-1.747084841,-2.505385354,-0.010843353,-0.030420885,0.039224281,-0.060000245,0.105202945,-0.026191568999999998,0.004337067,0.084261017,-1.438668815,-2.055500866,-2.606164566,-2.404606141,0.537557446,0.700131142,-14.62434725,-13.50058071,-12.86116742,-14.14083429,-13.24637798,-19.37277585,-9.087505455,-6.670060691000001,-1450.6749005443417 -3729,3729,R220I,0.032712336,0.06137694,-0.060326186,-1.622727732,-2.353178169,-0.011966478000000001,0.023220522,0.04220415,-0.041710966,0.012952749,0.109801131,-0.124575115,0.003922744000000001,-1.6467622419999999,-1.598693221,-2.735076747,-1.9712795909999998,0.948502581,0.708796263,-12.60486958,-11.82774434,-10.92513641,-14.18748773,-11.31427025,-14.76970917,-7.3335599060000005,-3.9712676730000003,-1446.9456524755806 -3730,3730,R220H,0.009439016,0.029295277999999998,0.02892705,-1.1843293129999999,-1.4760753469999999,-0.085799325,-0.01086206,0.029740091,-0.03464855,0.048042537999999996,0.010548018000000001,0.029431357000000002,0.028422742,-0.879343997,-1.4893146290000001,-1.5221362330000001,-1.43001446,2.789902573,2.197331546,-8.23991129,-8.997309113,-7.65426931,-7.93286705,-7.744955032000001,-8.870155945,-6.470422817,-4.564920165,-1445.9420431074686 -3731,3731,R220K,-0.015958948,0.022408149,-0.001500778,-0.036218533,-1.795858879,-0.09151713800000001,-0.014405971000000002,-0.017511923999999998,-0.001701507,0.064242208,-0.01942591,0.03902542,-0.042026975999999994,0.045237934,-0.117674999,-1.7485126180000001,-1.84320514,0.540058444,1.3041697079999999,-6.765942548,-5.88325724,-6.381748032000001,-7.583916618,-6.957897491000001,-7.022893356,-5.612307782,-1.321613255,-1453.9895606632344 -3732,3732,R220M,0.05056911,0.0006833039999999999,-0.011099600000000001,-1.557312971,-2.584173075,0.014297127,0.066382843,0.034755376,0.040326907,0.033201776,-0.031835168,-0.051865448,0.029666248,-1.7192672690000002,-1.395358672,-2.7106717610000004,-2.457674389,0.7249426659999999,0.6876679440000001,-13.69249079,-12.84961121,-12.72874238,-16.00241448,-11.92665916,-14.9550267,-8.613598877000001,-6.503826029,-1446.3188184825704 -3733,3733,R220L,-0.003707532,0.02374803,-0.062214075,-1.473826394,-1.5724576069999998,-0.039784775,-0.002244845,-0.005170219,-0.036002499,0.06997297599999999,-0.022476917000000003,-0.077417239,-0.047010910999999996,-1.3399301909999999,-1.607722597,-1.671282744,-1.473632469,3.31043286,2.4695464780000003,-11.1816478,-11.14716043,-9.72966774,-13.23164138,-9.125238434,-12.67453101,-7.123150442999999,-2.884932529,-1445.6298958570696 -3734,3734,R220N,0.056449047,0.033723154,-0.008871641,-1.654448986,-2.334290873,-0.046587683,0.077944683,0.03495341,-0.06454536599999999,0.001617618,0.06582869,-0.105505065,0.08776178400000001,-1.789633115,-1.5192648569999998,-2.422015664,-2.2465660819999997,0.9363217690000001,0.6935290120000001,-12.06991081,-11.63068803,-11.71998899,-12.70133691,-11.54882051,-12.74871962,-7.682893109,-4.685203522,-1446.6243277974427 -3735,3735,R220Q,-0.010781483,-0.002928433,-0.024666001,-0.837219853,-1.8367785090000002,-0.069753118,-0.037920922999999995,0.016357958,-0.081084822,-0.007694021,0.001837155,-0.066849361,0.017517359,-0.562185964,-1.112253741,-1.860015484,-1.813541534,1.817513216,1.45516832,-8.863474127,-8.119632751000001,-8.528393433,-9.98339225,-8.548515045,-9.137437157,-5.736047791,-3.5562334260000004,-1446.5132590169087 -3736,3736,R220P,-0.00830408,0.054148336,-0.612347998,-1.841706928,-2.0975707619999997,-0.055375802,-0.008306196,-0.008301964,-0.044711684,0.029807155,0.07848951700000001,-0.532583583,-0.6921124129999999,-1.775557694,-1.9078561619999999,-2.105316504,-2.089825019,3.231175122,2.046831322,-10.40492365,-11.47006301,-7.419134483,-10.62681299,-10.66990399,-11.83870377,-5.365955402,-0.753065333,-1439.4478974477388 -3737,3737,R220S,-0.044056316,0.04914365,0.043992352,-1.273530005,-1.917546496,-0.009241303000000001,-0.036562852,-0.051549779000000004,-0.034710707,-0.0033023859999999996,0.101589685,0.006487453000000001,0.08149725,-1.074905394,-1.472154615,-2.18319098,-1.6519020119999999,2.124196556,1.424208441,-10.8510185,-11.23494728,-9.291543007000001,-11.6561132,-10.01143958,-12.06104945,-6.705582532999999,-2.754874814,-1442.4496561759152 -3738,3738,R220T,-0.050152242,0.046440325,0.049117285,-1.56531545,-2.091349899,0.046932,0.0016972220000000002,-0.102001706,-0.044136774000000004,0.028957266000000002,0.063923383,0.026035172999999998,0.072199396,-1.430936365,-1.699694534,-2.243044458,-1.939655339,0.635994059,0.7067719140000001,-11.29876296,-11.29609029,-8.808989853,-12.74138766,-10.40615898,-13.24118801,-7.220746742,-3.0575098019999998,-1442.863386365585 -3739,3739,R220W,-0.008660303000000001,0.050848317999999997,-0.309149768,-1.8535074409999999,-2.373247326,0.087150357,-0.022652882000000003,0.005332277,-0.020885703000000002,0.002402567,0.099294069,-0.361571476,-0.256728059,-1.833403684,-1.8736111969999998,-2.52377818,-2.222716471,1.4499751719999998,0.743278537,-12.76040882,-12.28045736,-12.01479764,-13.06960883,-12.61656267,-13.82061761,-8.273217281,-5.709740312999999,-1452.9409914389253 -3740,3740,R220V,-0.053283579000000005,0.041751306,0.023613831000000002,-1.9471586090000002,-2.383732783,-0.000405249,-0.021952131,-0.084615027,-0.033201837000000005,0.014598845,0.06890376599999999,-0.00326251,0.050490172,-1.679878253,-2.214438964,-2.107011314,-2.660454251,0.728793715,0.690073638,-11.14999872,-10.42345905,-9.321664802999999,-12.83871162,-9.814937241,-13.35122092,-7.104713595,-3.256328392,-1445.3772829631343 -3741,3741,R220Y,-0.019912628,-0.0075080830000000005,-0.341932645,-1.75187665,-2.470586539,-0.014996641000000002,-0.009677584,-0.030147671,-0.07621079,0.005078817,-0.020094982,-0.37188369200000004,-0.311981598,-1.896194514,-1.607558785,-2.2855390140000003,-2.655634063,1.526687191,0.748963727,-14.14413983,-14.70015871,-13.54613392,-13.31502305,-13.63152787,-15.527855599999999,-9.262768053,-6.670061201,-1437.2335540703498 -3742,3742,S221A,0.013296002,0.021205007,0.012065204,0.050383564000000006,0.015870592,-0.076944536,-0.038312908,0.064904911,0.0077673709999999995,0.021880873,0.02052914,0.008652273,0.015478135,0.100515306,0.000251822,0.025711667,0.0060295159999999995,1.671448915,3.643209181,-1.347885735,-0.768136765,-1.635177101,-0.398970566,-1.405003159,-2.532141083,-2.723929683,1.5354776819999998,-1473.5191771266982 -3743,3743,S221C,0.018872096,0.044367091,-0.060994547,-0.011062431999999999,-0.009742219,-0.036717413,-0.010593238999999999,0.04833743,-0.031797666,-0.024359346,0.113093527,-0.129301454,0.00731236,0.016745958000000002,-0.038870822,-0.086562894,0.067078456,1.329819675,2.332032883,-8.475028043,-7.9702432860000005,-9.844140617,-7.725577065,-9.467887215,-7.36729203,-7.120383011,-4.502800562,-1461.6854101805948 -3744,3744,S221E,-0.084293674,-0.01159765,-0.008828179,-0.0040170729999999995,-0.210797204,-0.08826096,-0.0873062,-0.081281147,0.000692625,-0.035253112,0.012057812,-0.024128174,0.0064718169999999995,0.059884003,-0.067918149,-0.191099347,-0.23049506,1.622205036,2.3701220640000003,-6.1273384779999995,-5.949451447,-4.7322142110000005,-5.735446877,-6.772034812999999,-7.447545044,-5.966824107000001,-2.183214745,-1460.8972404878587 -3745,3745,S221D,0.057000389000000005,-0.052076572,0.026889536000000002,0.085300181,-0.568615666,-0.088083853,0.020151066000000002,0.09384971199999999,0.130017655,0.046892478,-0.151045622,0.02258654,0.031192532000000002,0.061664967,0.108935394,-0.37652401399999996,-0.760707318,0.7419947929999999,1.506499263,-8.225328279,-7.66687574,-8.49714093,-8.146097664,-8.555783196,-8.260743866,-5.254208108,-2.523986524,-1460.0743867876008 -3746,3746,S221G,0.014584463999999998,0.038798128,0.002388362,0.016935826,-0.267536734,-0.11102721199999999,-0.002535934,0.031704862,0.017457676000000002,-0.018081286999999998,0.095677543,-0.027189299999999996,0.031966023999999996,0.02879191,0.005079741,-0.276685301,-0.25838816600000003,1.143761305,1.803730218,-4.776545912,-5.210262978,-4.436986923,-4.250761993,-4.350130356,-5.634587311000001,-5.082922133,-0.133718807,-1462.122343712952 -3747,3747,S221F,-0.070243544,0.014366965,0.003140533,-0.053616917,-0.342966042,0.001359549,-0.052403838,-0.08808325,0.058813042,-0.118273065,0.147006994,-0.091397097,0.097678162,0.010529148,-0.11776298199999999,-0.475764663,-0.21016742100000002,0.835290152,1.492228805,-9.804486476000001,-10.00811293,-13.14730289,-7.119191322000001,-11.1129268,-7.634898438,-6.3667005020000005,-2.11258775,-1468.6903317733668 -3748,3748,S221I,-0.10987502699999999,0.09160843800000001,0.002263416,-0.023271166,-0.13567684,-0.112812016,-0.127954755,-0.09179529800000001,0.033566992999999996,0.034368902,0.148847973,0.058219267000000005,-0.053692435999999996,0.051290590999999996,-0.09783292199999999,-0.10456505099999999,-0.166788629,1.219628573,2.2200301380000003,-9.98848934,-9.573205688,-13.60964023,-8.773670402999999,-9.496280167,-8.489650215,-7.761173328,-5.00919614,-1462.1935701295733 -3749,3749,S221H,-0.04351564,-0.01818806,-0.070630896,-0.047033608,-0.000773092,-0.05471765,-0.071646828,-0.015384451,0.027273431,-0.037840857,0.001464738,-0.073761118,-0.06750067400000001,-0.007665661,-0.086401554,-0.077795603,0.076249419,1.37329066,2.431486283,-10.06415362,-9.153805969,-12.57953767,-8.187497459,-11.50255592,-8.897371094,-6.855869359,-3.240008175,-1457.9119835491292 -3750,3750,S221K,0.040610096,0.006747372,-0.076716811,-0.0350234,0.008597157,-0.11000638,0.079181246,0.002038945,-0.109005691,-0.125873709,0.139368452,-0.137313625,-0.016119996,-0.08828756900000001,0.01824077,-0.061371349000000006,0.07856566200000001,1.50874589,2.5125866130000003,-3.516416499,-2.834184685,-5.154495407,-2.5935548930000003,-3.256820854,-3.7430266569999997,-3.272027757,-0.97603211,-1454.5869038845412 -3751,3751,S221M,0.031015436,0.047522507,0.084795015,0.060518127000000005,-0.057603585,-0.190118953,0.028357162,0.033673708999999996,0.04745154,-0.022007565,0.117052578,0.016096061000000002,0.153493969,0.079094931,0.041941322,-0.15468965699999998,0.039482487999999996,1.385047423,2.23542946,-9.753989439,-9.062403824,-11.60557642,-8.741639473,-9.460783363,-9.899544113,-6.688578859,-4.211018905,-1464.4886557636783 -3752,3752,S221L,-0.05096451,0.034886939,-0.042189721,-0.011901386000000002,-0.16957654600000002,-0.085490355,-0.052174100999999994,-0.049754917999999995,-0.020368203999999997,-0.065489126,0.135263004,-0.073203319,-0.011176122,0.011908588000000001,-0.03571136,-0.23313843399999998,-0.106014657,1.29694063,1.9786941690000002,-8.037123225,-7.937766609,-10.80533835,-7.408326302000001,-7.638717079,-6.395467789,-5.585983425,-2.018267308,-1458.2441343124956 -3753,3753,S221N,-0.030863859,-0.041810837999999996,-0.032799748,0.04894479,-0.05864155099999999,-0.163050348,-0.050082992,-0.011644725,-0.06340283599999999,-0.035640356,-0.04798132,-0.038220985,-0.02737851,0.042168038,0.055721542,-0.08682381,-0.030459292000000002,1.1379451520000001,2.259826258,-7.162242485,-7.158728569,-8.213240372000001,-6.522565482999999,-7.867121353,-6.049556647999999,-6.50421611,-3.397661859,-1459.636275344994 -3754,3754,S221Q,0.010764663999999998,0.134913907,0.047908309,0.005510136999999999,0.10689935099999999,-0.08665038300000001,0.023684467999999997,-0.00215514,-0.004700571,-0.0371704,0.306998214,0.011794144,0.08402247300000001,0.037135601000000004,-0.026115327999999997,0.002330907,0.211467795,1.187935445,2.7137645339999996,-6.98031357,-7.105926674,-7.153206261,-5.635041885,-7.7253871,-7.282005927999999,-5.349842585,-1.717457855,-1462.560602184385 -3755,3755,S221P,-0.017998835,0.086741931,0.020574503,0.018894151,-0.663132229,-0.119810327,-0.035590001,-0.00040766800000000003,-0.009511951999999999,-0.008074316,0.181558177,0.007962381999999999,0.033186624,0.049044128,-0.011255826000000002,-0.678037496,-0.6482269620000001,0.613258414,1.381434036,-6.390957772999999,-5.563917061000001,-8.476049163999999,-4.840417931,-7.354306587000001,-5.7200981220000005,-5.086052801,-1.533751946,-1454.08769186493 -3756,3756,S221R,-0.029035473,0.050084472000000005,-0.019447645,0.020411612,0.03387427,-0.03652268,-0.03491845,-0.023152495,-0.015429868000000001,-0.025740937999999998,0.125909882,-0.021042041,-0.017853248000000002,0.063618305,-0.022795082,-0.012518433,0.08026697299999999,1.142929939,2.456704713,-7.29006297,-6.411211807000001,-10.06768165,-5.395402907999999,-8.38271785,-6.193300636,-4.77619101,-0.6646182820000001,-1444.405264195986 -3757,3757,S221T,0.04761746099999999,0.057470325,0.03653916,0.04819617599999999,0.009267263000000001,-0.074329206,0.02556399,0.069670932,0.023198196,0.015027918000000001,0.09991273199999999,-0.005586139,0.078664459,0.07427805700000001,0.022114295,-0.006062896,0.024597421,1.1524789770000001,2.655967199,-4.705452983,-4.372473824,-4.703663322,-3.789113907,-5.135373642,-5.526640221,-5.289556943,-2.457402045,-1462.574020889122 -3758,3758,S221W,-0.064746557,-0.040322853,-0.043348812,-0.013905715,-0.625610278,-0.111746914,-0.023374048999999997,-0.106119065,-0.020368203999999997,-0.050124605999999995,-0.030521100000000002,-0.035614267000000005,-0.051083357,0.05508432,-0.082895749,-0.5381537270000001,-0.7130668290000001,0.72662896,1.434049291,-12.16132428,-10.86875905,-14.86228707,-10.90045983,-12.86628578,-11.30882967,-8.459873712,-5.998991485,-1468.5516831865534 -3759,3759,S221V,-0.037365534,0.048904572,0.01075248,-0.011484771999999999,-0.06146742400000001,-0.09011260300000001,-0.081244208,0.006513141,0.011171408,0.0018004529999999998,0.09600869,-0.017843484,0.039348443,0.053341284,-0.076310828,-0.067540105,-0.055394742999999996,1.1988173229999999,2.316014929,-6.8813692,-5.833985687,-10.52621802,-5.939984795,-5.238935944,-6.8677215579999995,-4.452027842,-2.873215645,-1462.8362980629317 -3760,3760,S221Y,0.028502233999999998,0.054065074000000005,-0.04306758,-0.00507039,-0.10799013800000001,-0.160906523,0.033340549,0.023663918,-0.040761362,-0.053804132000000005,0.16193428,-0.058701498,-0.027433662,-0.026053127000000002,0.015912347,-0.145153073,-0.07082720299999999,1.329929066,2.153736191,-10.08620422,-9.817915702999999,-13.79009279,-7.678928177,-11.34765538,-7.7964290620000005,-6.178912442000001,-2.381206605,-1458.5429276376963 -3761,3761,A222C,-0.016669517,-0.08965373300000001,-0.015116536000000002,-0.08258270200000001,-0.139486071,-0.002048456,0.07240973,-0.10574876400000001,0.016064838,-0.14186067,-0.037446795,-0.000965403,-0.029267669,-0.09082368199999999,-0.074341721,-0.158143286,-0.120828856,1.3879482730000001,2.166400299,-5.915068031000001,-5.051879463,-6.235419556,-6.550109733999999,-6.620855087000001,-5.1170763169999995,-5.496373791,-4.130638746,-1466.5070899785496 -3762,3762,A222E,0.077525192,-0.04733885,-0.018074015,-0.002904115,-0.025283249,-0.08411219,0.14957188800000001,0.005478495999999999,0.011570546000000001,-0.004035767,-0.090641932,0.0038741220000000002,-0.040022152000000005,-0.004964739,-0.000843491,-0.017972302,-0.032594196,1.317512686,2.731157623,-3.25373109,-2.708708519,-3.485268822,-2.9577938610000003,-2.9073614119999998,-4.209522835,-2.752842573,-1.4248356130000002,-1451.271394182928 -3763,3763,A222D,0.009232568,-0.044418049,0.06622020299999999,0.017654796,-1.188570578,-0.096227727,0.09345099300000001,-0.074985857,0.021890037,0.012306697,-0.10114279400000001,0.069006666,0.063433739,0.029075077,0.006234514,-1.02824821,-1.348892945,0.544952934,1.336580847,-4.546954218,-3.678366013,-4.278986176,-4.479449806,-4.51753157,-5.780437523,-3.898611523,-0.805515128,-1453.5720380758867 -3764,3764,A222G,0.011585791000000002,-0.017558136999999998,0.006071433,-0.018605645,-0.205126728,-0.107007095,0.046599478,-0.023427896,0.030729267,-0.017904846999999998,-0.017211426000000002,0.03992867,-0.027785805,-0.034008354,-0.003202936,-0.19619887100000002,-0.214054584,1.511576925,2.2266338230000002,-3.824290279,-2.862698364,-4.676835037,-3.6444411239999996,-3.653767235,-4.283709633,-2.7518254260000004,1.988226609,-1467.2093432690017 -3765,3765,A222F,0.128752507,-0.00666986,0.081682797,0.030495897999999997,-0.604300296,-0.061213862,0.17269073899999998,0.08481427400000001,0.070406951,-0.143993677,0.130653957,-0.01864422,0.182009814,-0.004620198,0.065611993,-0.629344174,-0.5792564170000001,0.839728922,1.44451655,-5.349680391000001,-5.967559227000001,-3.699526833,-6.050998459,-5.451745461000001,-5.578571976,-4.547390027,-1.6144639969999999,-1462.8335951971821 -3766,3766,A222I,0.009843044,-0.055860865999999995,0.066835569,-0.052945730999999996,-0.127924825,-0.222302012,-0.019505985,0.039192072,-0.011433131000000001,-0.043916227,-0.067805504,0.11336313199999999,0.020308006,-0.11732447800000001,0.011433016,-0.102199902,-0.153649748,1.3996322890000001,2.270579901,-1.159869939,-0.361999245,-1.3234991459999998,-1.533815506,-1.462224159,-1.117811638,-3.866328422,-2.668206369,-1463.6807624576613 -3767,3767,A222H,0.069385264,0.007654783,0.021255012,0.036850787,-0.080251335,-0.101127496,0.125623744,0.013146783,0.00622198,-0.039392347,0.054701913,-0.035733336,0.078243359,-0.056847338,0.130548912,-0.13557676,-0.024925909,1.416113825,2.236840716,-3.507843648,-1.380369675,-3.190487755,-5.13312175,-3.890944672,-3.9442943880000003,-2.592144486,-1.697351478,-1460.753924518358 -3768,3768,A222K,0.235088397,0.07222701599999999,0.089258401,0.058121448,0.135756478,-0.132984593,0.41995045700000005,0.050226337,0.040576987,0.05394058,0.090513452,0.047231559000000006,0.131285242,0.006749417,0.109493478,0.010036136999999999,0.261476818,1.069398933,2.43860654,-4.448323361,-3.0523050310000004,-3.759271591,-5.185012459,-4.0948066480000005,-6.150221077,-3.5941859289999996,-1.173238727,-1453.317300804425 -3769,3769,A222M,0.0050857559999999994,0.018102366,-0.08541638300000001,-0.071236818,-0.314588866,-0.054420422999999996,0.069435098,-0.059263587,-0.05917305900000001,0.025288317999999997,0.010916414,-0.02184936,-0.148983405,-0.093739966,-0.04873367,-0.080655932,-0.5485218000000001,1.138072556,2.134023299,-5.735192502,-4.006751396,-3.905764908,-8.425750946,-5.4672763060000005,-6.870418953,-4.601691763,-1.5981526869999998,-1466.4250702746212 -3770,3770,A222L,0.032905125,-0.011462805,0.041377807,0.004574363,-1.220598653,-0.127724715,0.064336742,0.001473508,0.037593154,0.00075709,-0.023682698999999998,0.04558834,0.037167274,0.00041224,0.008736485,-1.141003267,-1.300194039,0.760138953,1.34874475,-3.492198415,-1.6061128230000001,-1.567982651,-6.180989342,-4.578330528,-3.5275767289999997,-3.71999773,0.216618074,-1461.1358081065118 -3771,3771,A222N,-0.042167086,-0.04235562,-0.015291484,-0.004257116,-0.165455814,-0.063853172,0.047043826,-0.131377997,-0.162032404,-0.060016013,-0.024695227,-0.058572167,0.0279892,0.039798942000000004,-0.048313173,-0.146827887,-0.18408374,1.33464925,2.175488138,-5.345698087,-4.446358299,-5.880059372000001,-6.279324989,-5.652697975,-4.470049797,-3.9737792389999997,-1.709857225,-1461.1898797242902 -3772,3772,A222Q,-0.071985992,0.05277210400000001,-0.021736684,-0.081044915,-0.035363378,-0.142716184,-0.05416115,-0.089810833,-0.044780495999999996,0.014253018999999999,0.09129118800000001,-0.018454943999999997,-0.025018422999999998,-0.053622743,-0.10846708699999999,-0.14106438599999999,0.07033763,1.214426495,2.065198127,-3.5298346310000004,-2.68050824,-2.628748772,-4.151490685,-3.491928917,-4.6964965439999995,-4.206015428,-0.462552009,-1461.0960251665674 -3773,3773,A222P,0.019195523,-0.019155099999999998,0.007502622,-0.0070013340000000006,-0.20669553,-0.085291619,0.050764192,-0.012373146000000002,0.005303771999999999,-0.01280776,-0.02550244,0.023083459,-0.008078216,-0.011911868999999999,-0.002090799,-0.194006923,-0.219384136,1.543956029,2.264664722,-6.196590297999999,-5.672433441,-5.457395241,-5.8073669279999995,-6.823813727999999,-7.221942154,-5.053539579,-1.7113810130000002,-1452.2204723372124 -3774,3774,A222S,0.018724452,-0.044909162999999995,-0.00795535,-0.014477048000000001,-0.084670226,-0.070895657,0.096907899,-0.05945899599999999,0.043756915,-0.055259351,-0.034558975,-0.005554094,-0.010356605999999999,-0.039837301,0.010883206000000001,-0.106603945,-0.062736506,1.287981567,2.198020287,-0.7343780459999999,-0.184530312,-1.564515717,-0.9189556809999999,-0.287408966,-0.716479553,-1.386100088,-1.08074493,-1462.709373908583 -3775,3775,A222R,0.092091915,0.009459268,0.000608778,0.0077223380000000005,0.012398433,-0.100592322,0.09865269300000001,0.085531137,0.01527745,-0.045907120999999995,0.06482565700000001,-0.045509694,0.046727249000000005,-0.046906362,0.062351038,-0.046128088,0.070924953,1.303740555,2.449109932,-4.010011943,-2.33474852,-4.46643689,-4.661193237,-4.7642013169999995,-3.823479752,-2.7573088489999997,-1.17503294,-1453.382905665785 -3776,3776,A222T,0.0033600059999999996,0.01135333,-0.008364168,0.008498593,-0.052968743,-0.109575344,0.020858174,-0.014138163,-0.017187222,-0.020878871,0.043585531,0.001151956,-0.017880292,0.020173716,-0.003176531,-0.040979728,-0.064957758,1.2333858640000002,2.446336745,-1.794014113,-1.9327110369999998,-1.9368624190000001,-1.7860134509999999,-1.9385584869999999,-1.375925171,-3.1734086660000003,-2.51385407,-1460.2276570289396 -3777,3777,A222W,-0.003783173,-0.031795399,0.01776065,-0.001784315,-1.279806225,-0.09870786,-0.011950693,0.004384348,0.056525603,-0.102879388,0.03928859,-0.014093895,0.049615195,-0.062331502000000004,0.058762873,-1.270249661,-1.289362788,0.923678207,1.3597565440000001,-8.583818443,-6.975166878,-8.538917351,-9.055075874,-8.232452126,-10.11747999,-5.913620087000001,-4.060091644,-1463.4218273307197 -3778,3778,A222V,0.018111133999999997,-0.008535191999999999,-0.020136526999999998,-0.057140678,-0.038754442,-0.083972576,0.040061649,-0.003839381,-0.019038025,0.018670547,-0.035740931000000004,0.036948102999999996,-0.077221157,-0.081226168,-0.033055187,0.025505051,-0.103013935,1.255597429,2.862599988,2.269701924,2.360969681,2.282687073,1.8649062809999999,2.4394513019999997,2.400495285,-0.069132053,-1.175615759,-1466.174078503158 -3779,3779,A222Y,0.162187481,-0.022068089,0.010535828,-0.013866402,-0.274795451,-0.176021625,0.218252273,0.106122688,0.024970864,-0.09010510000000001,0.045968922,-0.055390508,0.076462164,-0.040181374,0.01244857,-0.416263424,-0.133327477,1.7119830169999999,2.076329274,-4.919914835,-3.1250786589999997,-2.9464520110000003,-6.278086662000001,-5.564075462000001,-6.6858813779999995,-4.163625201,-0.20548800600000003,-1456.496600387618 -3780,3780,L223A,-0.01622418,0.01503737,0.0007258710000000001,0.020766215,-0.244925714,0.0186056,-0.047784640999999996,0.015336282,0.011096528,0.00955909,0.02051565,0.003388053,-0.001936311,0.007964207,0.033568222,-0.253065375,-0.236786052,1.668595501,2.259885159,-7.905869034,-7.419652771,-7.473060516,-8.629637367,-7.5664908220000004,-8.440503693,-4.398811554,-2.897793467,-1455.1818432980217 -3781,3781,L223C,0.011245554,-0.024437723999999997,-0.052557504000000005,-0.025110556000000003,-0.05901323,0.076046747,0.008189446999999999,0.014301661,0.025155486,-0.11358167599999999,0.064706228,-0.121881357,0.016766349,-0.130483171,0.08026206,-0.142579074,0.024552615,1.48279952,2.211063669,-10.74498275,-10.74852754,-10.70893054,-10.69626759,-10.45178165,-11.11940641,-8.669689527000001,-7.3263794120000005,-1455.5492700901814 -3782,3782,L223E,-0.09717524,-0.006813721,-0.89948057,-2.3642507530000003,-2.5012192069999997,0.025868121,-0.11252812400000001,-0.081822356,-0.148741651,-0.08975699300000001,0.076129552,-0.757536795,-1.041424345,-1.919320589,-2.8091809160000003,-2.618152041,-2.384286373,2.063227267,0.8942876129999999,-11.62764005,-10.51035503,-11.20667743,-12.37671854,-11.04185017,-13.00259906,-8.674282246,-7.3263794120000005,-1457.0948637174442 -3783,3783,L223D,0.021922375,-0.17191759899999998,-1.346041808,-2.2176567780000003,-2.442670862,0.000637861,0.008065714,0.035779035,-0.096910013,-0.075398843,-0.268436355,-1.306744479,-1.385339136,-2.2167163,-2.218597255,-2.614517756,-2.2708239669999997,0.94060404,0.096316325,-12.059419,-11.00098691,-12.27431371,-12.92290222,-10.75431664,-13.344575500000001,-8.293958587,-6.935782681,-1454.724260260351 -3784,3784,L223G,-0.003895253,-0.002914425,0.02203797,-1.455733325,-2.276690172,0.073134148,-0.032843647000000004,0.025053142,0.029963222999999997,-0.052279198,0.046450349,0.02910497,0.01497097,-1.362397224,-1.549069425,-2.429205461,-2.1241748819999997,0.622004561,0.7097921140000001,-12.02632829,-11.49228792,-11.76791464,-13.01556802,-11.40158453,-12.45428636,-8.696329311,-7.96929821,-1452.4496167162433 -3785,3785,L223F,-0.024977389,-0.002282364,-0.043612912999999996,-0.358286469,-1.850101859,-0.15845328,-0.075456522,0.025501745,0.202104691,0.043582285,-0.048147012,-0.10432428099999999,0.017098456,-0.24837930800000002,-0.46819363,-2.044120773,-1.656082944,1.3207584079999999,1.325351849,-4.8695852219999995,-6.0329092179999995,-6.314973579,-3.9716454160000003,-4.072522347,-3.955875549,-5.004782496,-1.803275865,-1456.7257606862113 -3786,3786,L223I,0.057002232,0.10078527400000001,0.090042963,0.047262776,0.039474143999999996,0.050420747,0.036854142,0.077150321,-0.079181246,0.040202545,0.16136800199999998,0.082627676,0.097458249,-0.058634451,0.15316000300000002,-0.008086394,0.087034681,1.3061426740000002,2.5487605330000003,-4.430108545,-4.33567762,-4.255954102,-5.657927521,-3.5620250089999996,-4.338958473,-4.195036769,-1.9215919119999998,-1461.3349814419635 -3787,3787,L223H,-0.008521296,-0.026784217000000003,-0.148113904,-1.7012661169999999,-2.545721245,0.023673537999999997,0.015602982,-0.032645574,-0.071315413,0.0009862319999999999,-0.054554665999999995,-0.128015415,-0.168212392,-1.61042476,-1.792107474,-2.3440183180000003,-2.7474241719999997,1.002539858,0.7181881729999999,-10.81228895,-10.78739301,-10.48500703,-11.43800291,-9.549676071,-11.80136574,-7.896500983999999,-6.176094325,-1452.7415138636716 -3788,3788,L223K,-0.047470387,0.099646223,0.0393871,-0.013767563,-1.6884486630000002,-0.045375349,0.005877123000000001,-0.10081789699999999,0.057991947,0.101311422,0.09798102300000001,-0.012626478,0.09140067800000001,-0.08748448,0.059949355,-1.641633136,-1.73526419,0.569519494,1.3087406240000001,-11.77766974,-11.59719617,-11.98750078,-12.00763389,-10.37262052,-12.92339734,-8.037370424,-7.065231075,-1453.6353189870715 -3789,3789,L223M,0.021106207999999998,0.11616370300000001,0.122654043,-0.013270968000000001,0.006047271999999999,-0.10643216900000001,0.014021532,0.028190884,-0.029963222999999997,0.080504722,0.151822684,0.127824425,0.117483661,-0.020595408,-0.005946526999999999,0.017331706000000002,-0.0052371629999999995,1.006743881,2.549018873,-4.7081482569999995,-5.997968605,-4.654316017,-3.8438911510000002,-4.413504776,-4.631060738,-3.786231373,-2.83668985,-1466.1859541498125 -3790,3790,L223N,0.022667768999999997,-0.061991581,0.030404971,-1.431332535,-1.938482333,0.034348286,0.000300097,0.04503544,0.039152123999999996,0.033203177,-0.157186338,0.022190843,0.038619099,-1.5805020330000001,-1.282163036,-1.978303488,-1.8986611780000002,0.9768368629999999,0.709803886,-11.5227623,-11.12206615,-10.85744679,-12.19336495,-10.56183924,-12.87909437,-8.010345323,-6.255310565,-1454.0741942096502 -3791,3791,L223Q,-0.0255447,0.067104691,0.029605576,-0.71343107,-1.936262751,0.154440689,0.070132223,-0.12122162199999999,0.10011515300000001,-0.008933799999999999,0.14314318199999998,-0.02077823,0.079989382,-0.266108075,-1.160754065,-2.182423471,-1.690102031,1.2690968440000001,1.303578407,-10.27065863,-9.35040255,-9.963642426,-11.36048344,-8.922516006,-11.75624871,-7.442353359,-5.812606262999999,-1463.4374612853862 -3792,3792,L223P,-0.015115276,0.013079278,-0.566095238,-1.8292151680000002,-2.182385851,0.005690359,-0.037197308,0.006966756,0.019878148,-0.021559041,0.047717597,-0.451164165,-0.681026311,-1.8801196869999999,-1.7783106480000002,-2.446325573,-1.918446129,1.637591424,0.778482474,-11.71129259,-11.63045922,-11.37951077,-12.74659602,-10.96383489,-11.83606207,-9.03275832,-8.129810363999999,-1452.5758185666054 -3793,3793,L223S,-0.03489905,-0.007726068000000001,0.02858973,0.035860624,-1.648996795,0.037198629,-0.033105354,-0.036692745,0.042860252,-0.038710074,0.023257939,-0.010300126,0.067479585,0.032698836,0.039022412,-1.5654185390000002,-1.732575051,0.5943539210000001,1.312231164,-9.821718893,-9.656863091,-8.981269913,-10.79818472,-9.346191681,-10.32608507,-7.0455155629999995,-5.676442226,-1451.1167311989702 -3794,3794,L223R,0.003223101,-0.0027083420000000003,0.018615603999999997,-0.11871141800000001,-1.7008867980000002,-0.010231094,-0.01815188,0.024598082,0.0030888779999999998,-0.02276727,0.017350587,-0.015271156000000001,0.052502362999999996,-0.064248087,-0.17317474800000002,-1.899498092,-1.5022755030000001,0.9205724679999999,1.310891641,-10.64141882,-9.78075544,-10.12378861,-11.76364992,-9.337649635,-12.2012505,-7.744141443999999,-6.138711878,-1454.1505416380242 -3795,3795,L223T,0.029845299,0.060832322,0.028537463,0.047910582,0.004756221,0.033113624,-0.0029601109999999996,0.062650708,-0.033471482999999996,0.032979594,0.088685049,0.030050612999999997,0.027024312,0.026472345,0.06934881799999999,-0.040222142999999995,0.049734584000000005,1.462413316,2.7457175389999997,-7.985387666,-8.331459152,-7.451654381,-8.406871681,-7.558410065,-8.178543053,-5.16574992,-3.914584847,-1456.0286597930826 -3796,3796,L223W,-0.063666269,0.035789054,-0.053210089,-1.911610452,-2.592646951,0.059376444,-0.06622663599999999,-0.061105901,0.012774288,0.037347805,0.034230302000000004,-0.036220915,-0.070199263,-1.4721625580000002,-2.351058346,-2.414032058,-2.771261843,0.7628318390000001,0.7129528359999999,-9.260689902000001,-9.210002907,-9.44861528,-9.289189056,-8.190283142,-10.16535912,-7.534111542000001,-5.249384518,-1462.143508600071 -3797,3797,L223V,0.008292021,0.043944047,0.098212225,0.064780038,0.023457895,0.02904686,-0.025547663999999998,0.042131706,0.015794267,0.008706848,0.079181246,0.076890746,0.119533704,0.072191301,0.057368775,-0.020315368,0.067231158,1.198314174,2.605887215,-3.9200504819999997,-4.06213221,-3.8620307769999997,-4.690224831,-2.775757729,-4.210106865,-3.920741057,-1.195345552,-1462.7899070414715 -3798,3798,L223Y,-0.008152962,0.039692702999999996,-0.192914747,-1.9015007169999998,-2.1265148,-0.008984502,-0.048289795999999996,0.031983872999999996,0.09247084800000001,-0.060793297,0.14017870300000002,-0.216474261,-0.169355232,-1.4274760780000002,-2.375525355,-2.302398788,-1.950630812,2.305009211,1.378185901,-9.825856645,-10.82243559,-10.91263068,-9.708652855,-8.210140732000001,-9.475423362999999,-7.628486028999999,-5.773600201,-1451.859590656124 -3799,3799,P224A,-0.043017932,-0.001777951,-0.036393722,-0.142841371,-1.655145079,-0.026180387000000003,-0.012111798,-0.073924066,-0.025847882000000003,0.018405448,-0.021961348999999998,-0.042945743,-0.029841701,-0.035188712000000004,-0.250494029,-1.800008258,-1.5102818999999998,0.76686957,1.309204888,-6.756226282,-6.725311134,-7.805786743,-5.776037682,-6.4671285020000004,-7.006867347999999,-6.647958967,-3.76872266,-1472.4463358065113 -3800,3800,P224C,-0.011596533999999999,0.027544647000000002,0.038411022,-0.8779894709999999,-2.236007119,-0.02648039,0.0056471180000000004,-0.028840186,-0.035634707,-0.004454533,0.059543827,0.09496324099999999,-0.018141198,-0.377564445,-1.3784144969999998,-1.962130348,-2.50988389,1.460913057,1.353243587,-10.43475911,-9.647742103999999,-11.74862837,-9.393007277999999,-9.591370384,-11.79304742,-9.077983613999999,-7.186463626,-1472.2472162493505 -3801,3801,P224E,-0.035172761000000004,0.046367644000000006,-0.000937916,-0.029731004,-1.914921366,-0.030517181,-0.059532836,-0.010812686,-0.072918568,0.0053218219999999995,0.087413466,-0.07586155,0.073985719,-0.03983953,-0.019622478,-1.664510421,-2.165332311,0.572917774,1.3073025440000001,-7.576746555,-7.556325745,-8.100586853,-6.54115641,-6.934353729,-8.751310036,-6.420307827999999,-3.9775846710000002,-1471.5465614260174 -3802,3802,P224D,-0.033585864,-0.026019976,-0.014224496000000001,0.005120009,-2.002474635,-0.000570368,-0.037950318,-0.029221409,0.034125862,-0.02648143,-0.025558521,-0.02508796,-0.003361032,-0.037677512,0.047917529,-1.6369666719999998,-2.367982598,0.790422107,1.317627204,-7.140060559,-7.3235326689999996,-8.346831421000001,-6.161024925,-5.875889992,-7.9930237879999995,-6.013145999,-3.5958751089999996,-1474.5373590840027 -3803,3803,P224G,-0.012840932,0.056897012000000004,0.011608398,-0.01224639,-1.271180378,0.041937008,0.010892192,-0.036574055,-0.017412843,0.012490652,0.10130337199999999,-0.004107239,0.027324035,0.01273982,-0.037232599,-1.171968673,-1.370392083,0.650722525,1.336324529,-7.536133981,-6.84745649,-8.935062103,-6.840902092,-6.608627396,-8.448621826,-6.624518817999999,-2.992341218,-1469.0530500113964 -3804,3804,P224F,0.013097485,-0.0036308259999999998,-0.09396750400000001,-1.969081501,-2.3177489,-0.081460861,0.027289499,-0.001094529,-0.007266823,-0.069147843,0.06188619099999999,-0.164749954,-0.023185052999999997,-1.815828763,-2.122334239,-2.3359366759999998,-2.299561123,1.130635711,0.70552332,-12.10072019,-10.91148515,-13.62875553,-10.72770535,-10.48105875,-14.75459618,-10.51650051,-10.289760800000002,-1463.130188754294 -3805,3805,P224I,-0.10203846300000001,-0.019671977,-0.13338539900000002,-1.8856398730000001,-2.345231646,-0.003216405,-0.100328279,-0.103748646,-0.19836200399999998,-0.022680141,-0.016663813,-0.155630574,-0.11114022400000001,-1.40689337,-2.364386375,-2.449880029,-2.240583263,1.036205686,0.747084567,-11.18310001,-9.606468536,-12.60415779,-9.130787895,-10.73356805,-13.84051776,-8.995547511,-6.918983342000001,-1465.0521164452657 -3806,3806,P224H,-0.079697336,-0.012347118999999998,0.017517412,-0.042706376,-1.47636862,0.007711568,-0.089324902,-0.070069769,-0.014445408,0.02912063,-0.053814867,0.01734668,0.017688144,0.035114513,-0.12052726400000001,-1.552715024,-1.400022215,0.384268978,1.304825418,-8.705838692999999,-7.7758074420000005,-10.26796344,-7.465959152000001,-7.150994904,-10.86846853,-7.567734486,-5.410661625,-1466.4462840151973 -3807,3807,P224K,-0.069300817,0.161145901,0.074943041,-0.030139985,-0.676098286,0.06871405900000001,-0.10624941,-0.032352223,0.248796027,0.012081965,0.310209836,0.064522814,0.08536326699999999,-0.136602817,0.076322848,-0.909967944,-0.44222862700000004,1.432759724,1.5922158469999999,-8.160721033,-7.514103317000001,-9.183115562000001,-7.109516212000001,-6.867062675,-10.1298074,-7.33171222,-5.096049949,-1467.9731635013595 -3808,3808,P224M,0.035407308,0.021170956,0.051235987999999996,-1.051878651,-1.9145604109999999,-0.175249005,0.037586829,0.033227786,-0.11918075800000001,0.021665583,0.020676328,-0.040327927,0.142799903,-0.706129993,-1.3976273080000001,-1.953236634,-1.8758841880000001,1.9205537190000002,1.45360928,-10.10780444,-9.107720955,-11.53885885,-8.871430885,-9.186659477000001,-11.83435202,-8.599491297,-6.4425002220000005,-1467.6149426619522 -3809,3809,P224L,-0.05968981,0.000158413,-0.033260264,-0.911043918,-1.96066277,-0.024097264,-0.049401175,-0.069978444,-0.031450362999999995,-0.013925393000000001,0.014242218000000001,-0.044916192,-0.021604335,-0.437049656,-1.38503818,-1.8149924309999999,-2.106333109,1.638867475,1.414121074,-8.515475665,-7.4973025820000005,-10.21889217,-6.914930152999999,-7.30037307,-10.64588035,-7.089378791000001,-4.538880852,-1460.9805051274598 -3810,3810,P224N,-0.056307478,0.13864996300000001,-0.048755344000000006,0.07126316,-1.7892447669999998,-0.023253196,-0.08125882200000001,-0.031356134,0.107466874,0.14833061,0.128969315,0.080046375,-0.17755706300000001,0.157389673,-0.014863353000000001,-1.7212875580000002,-1.857201975,0.5480635939999999,1.3051956470000001,-8.203406853999999,-7.881507881,-9.584591934,-7.352781403,-6.6924887239999995,-9.50566433,-7.319715297999999,-4.715187857,-1471.9610244729556 -3811,3811,P224Q,-0.13977319900000001,-0.002776924,-0.061100645,-0.023895898999999998,-1.537817744,0.07483943900000001,-0.104804169,-0.174742229,-0.052233969000000005,-0.005292130999999999,-0.000261716,-0.06535114,-0.05685015,0.11969716300000001,-0.167488961,-1.445081146,-1.630554342,0.590954057,1.317453745,-8.002327081,-7.353986671,-9.033731208999999,-6.938495041,-7.300184135,-9.38523835,-7.5139940979999995,-4.853308932,-1471.9325661361217 -3812,3812,P224S,-0.008349018,0.024780352999999998,0.015201058,0.005914849,-1.439181992,-0.012389198999999998,-0.009926373,-0.0067716619999999995,-0.011102828,0.030487623999999998,0.019073081000000002,-0.016481808,0.046883924,0.024361942999999997,-0.012532245,-1.3842772380000001,-1.494086746,0.7774842129999999,1.334834136,-6.353520972999999,-5.875726967,-7.35468499,-6.175396217,-5.6576259989999995,-6.704170692000001,-5.83230788,-3.51359045,-1469.7195933246985 -3813,3813,P224R,-0.02755549,0.035047398,-0.012817569,-0.024783169,-1.512772675,0.028531857999999997,-0.012363096,-0.042747883,0.031283659,-0.000654856,0.070749651,-0.062249381,0.036614243,-0.008291128,-0.041275209,-1.538553041,-1.486992308,0.670212756,1.318099578,-7.909425864,-7.068386932,-9.649589073,-6.466253876000001,-7.317275787000001,-9.04562365,-6.256958472000001,-4.2432981,-1465.2853863011114 -3814,3814,P224T,-0.025098662999999997,-0.009297145,-0.015234195,-0.019709311,-1.37993249,0.0011543060000000001,-0.031481578999999996,-0.018715746000000002,-0.050878915,-0.05394096,0.035346671,-0.013345107,-0.017123283,0.014791453999999999,-0.054210075,-1.526045945,-1.233819035,0.6576556020000001,1.31723811,-7.954760509,-7.21993235,-9.120237213,-7.1270816120000005,-7.6873781889999995,-8.61917318,-7.496268219,-4.503390371,-1470.930554728955 -3815,3815,P224W,0.15532373800000002,0.104441202,-0.314811937,-1.189150345,-1.887302746,-0.135060882,0.22880711,0.081840366,-0.028752872999999998,-0.18138339,0.390265794,-0.44749688200000004,-0.18212699100000002,-1.754277005,-0.624023685,-2.399323655,-1.375281837,1.735409644,0.8382576209999999,-10.71430771,-9.152137413,-12.33322221,-9.429019843999999,-9.661503189,-12.99565588,-9.116961557,-6.903278074,-1464.4816077793948 -3816,3816,P224V,-0.038828877000000005,-0.007651876,-0.029235933999999998,-1.322304502,-2.5054752909999998,0.027574585,-0.019703729,-0.057954025,-0.009280475,-0.050293669000000006,0.034989917999999995,-0.029579841000000003,-0.028892027,-1.039446535,-1.605162468,-2.22856123,-2.782389352,0.8134078440000001,0.7601475320000001,-9.825943521000001,-8.655365234,-11.46084232,-7.761640915,-9.751205711,-11.50066342,-8.178654647,-5.507813129,-1468.4415877079591 -3817,3817,P224Y,-0.10605901,0.016535638999999998,-0.013409187,-1.6987293330000002,-2.260381099,-0.001388359,-0.099498752,-0.112619267,0.068059863,-0.05165239,0.084723668,-0.08731696,0.06049858599999999,-0.955539224,-2.4419194419999997,-2.202645866,-2.318116331,2.052593775,1.4004838769999999,-10.73663522,-9.245885048,-12.36798798,-9.373981468,-9.165609955,-13.52971162,-9.093148246,-6.903278112000001,-1462.3499974193983 -3818,3818,A225C,0.017269176,-0.026362137999999997,0.002254677,0.011390376,-0.100035783,0.005161288,-0.046757596,0.08129594799999999,0.111255729,-0.043864969000000004,-0.008859305999999999,-0.031088152,0.035597505,-0.0031266420000000002,0.025907392999999997,-0.107525935,-0.092545631,1.41491968,2.307297164,-6.6443769360000005,-6.5785547410000005,-6.79270018,-6.443468482999999,-6.904498505,-6.502662773,-7.231797202999999,-6.501824432,-1462.3013366414234 -3819,3819,A225E,-0.123036721,-0.105161037,-0.046598694,-0.019734283999999998,-0.084060168,-0.012837237,-0.193889195,-0.052184246,0.08748605699999999,-0.09562286699999999,-0.114699207,-0.018654179,-0.074543209,0.07010363,-0.109572197,-0.052449372,-0.115670964,1.3566037219999998,2.615959336,-0.9488170229999999,-0.556728256,-0.19142511,-1.4780965190000002,-1.952691025,-0.565144203,-1.099744142,-0.432427558,-1464.5071870042011 -3820,3820,A225D,0.052145342000000004,0.061116697000000005,0.026594272999999998,0.020426556000000002,-0.024881322,0.014741518,0.036573576000000003,0.067717107,0.05844381,0.036707661,0.085525732,0.031345173999999996,0.021843372000000003,0.030323987,0.010529123999999999,-0.061205982,0.011443338,1.309040408,2.490008569,-1.660967979,-1.670252892,-0.868933975,-2.081638298,-2.592804848,-1.091209885,-2.382661916,-0.35516354299999997,-1459.9906930276193 -3821,3821,A225G,-0.021080223999999998,-0.032623571000000004,-0.013176321999999999,-0.01588891,-0.082549558,0.007140723000000001,-0.057071062,0.014910615,-0.007557273000000001,-0.003507058,-0.061740084,-0.022179235,-0.004173409,-0.020063097,-0.011714723,-0.05297309,-0.112126025,1.375386059,2.490627003,-2.5715133619999997,-3.1652006839999998,-2.230569252,-2.291406479,-3.173623825,-1.996766571,-3.178321663,-1.986585295,-1459.0203549647704 -3822,3822,A225F,0.012164017,-0.017228241000000002,-0.067781864,-0.008420174,-0.16448658800000002,-0.066225441,-0.046034298,0.070362332,-0.052393029,0.025349682000000002,-0.059806162999999996,-0.071132793,-0.064430935,-0.040317887999999996,0.02347754,-0.115565111,-0.213408065,1.363340166,2.209659556,-6.077455562999999,-6.0910245739999995,-5.93890033,-5.91553968,-6.929479507000001,-5.512333725,-5.29973337,-4.417117756000001,-1459.8724123295397 -3823,3823,A225I,-0.008786755,-0.086589304,-0.01092792,0.06226434,-0.067274635,0.00110001,-0.113523468,0.095949959,-0.054486019000000004,-0.051096029,-0.12208257800000001,-0.023708142999999997,0.0018523029999999998,-0.025101922000000002,0.149630601,-0.12661232,-0.00793695,1.31588563,2.2093289130000002,-4.6851571430000005,-3.9923542710000004,-4.53245137,-4.8019976810000005,-5.232195267,-4.866787125,-4.746965367,-4.119208708,-1463.1392502798699 -3824,3824,A225H,0.029723127999999998,-0.075093041,0.016963599,0.0011125689999999999,-0.076997698,-0.001974937,-0.001110047,0.060556302,-0.00675396,-0.08057388900000001,-0.069612193,0.004872611,0.029054586,-0.030572701,0.032797837999999996,-0.041428285,-0.112567111,1.311469748,2.424453589,-4.211403418,-4.571279221,-4.181038971,-3.733018448,-5.071993492,-3.4996869580000003,-4.0473252980000005,-3.220453862,-1460.3764051306061 -3825,3825,A225K,-0.148695717,-0.034365795,-0.094658811,-0.014837452,-0.037823987999999996,0.082731238,-0.320280172,0.022888738999999998,0.065313078,0.027824302000000002,-0.09655589099999999,0.062406115,-0.251723737,0.068021586,-0.097696489,0.13225969,-0.207907665,1.151940518,3.077378005,-0.782812352,-0.69283844,-0.283972809,-0.7010866170000001,-1.6045138319999999,-0.6316500629999999,-1.9903555659999999,-0.389093481,-1463.5836944747716 -3826,3826,A225M,-0.057493755,-0.078365413,0.054043667000000004,-0.023300991,-0.048778137,-0.049142832000000004,-0.13633176,0.021344251,-0.079702807,0.076502205,-0.23323303,0.091594505,0.016492829,-0.068346612,0.02174463,0.048512426,-0.146068699,1.118077568,2.6982633689999997,-4.993606757,-4.686563904,-4.779492858999999,-5.315409767,-5.4346502,-4.751917053000001,-5.232160787,-4.307322029,-1465.090904809069 -3827,3827,A225L,-0.021005656,-0.076143294,-0.019279668,-0.028526079,-0.130718286,-0.01122536,-0.09153752300000001,0.049526212,-0.035036231,-0.05116310599999999,-0.10112348199999999,-0.046999112999999995,0.008439778,-0.053972769000000004,-0.0030793879999999997,-0.091974795,-0.169461776,1.4055818780000002,2.302168178,-4.223655783,-3.8263709789999996,-4.3408155289999995,-4.518628075,-4.75940963,-3.673054703,-5.152114678,-3.055797478,-1459.8566860677674 -3828,3828,A225N,0.032214445,-0.028770424,-0.019696102,0.076029205,-0.054190920999999996,0.0382627,-0.011809746000000001,0.076238636,0.054575955999999995,-0.085459816,0.027918969,0.049258315999999996,-0.088650519,0.05356567,0.09849273900000001,-0.007299239,-0.101082602,1.272442012,2.737469258,-2.848377235,-3.177025925,-2.44598616,-2.549922005,-3.5373616180000003,-2.531590469,-3.2964334980000003,-2.506198964,-1461.3646661788225 -3829,3829,A225Q,-0.014750981000000002,-0.129096663,-0.06423234900000001,-0.09174298199999999,-0.146481261,-0.07110552,-0.045210942000000004,0.01570898,-0.05786576,-0.145202953,-0.112990373,-0.038463676,-0.09000102199999999,-0.028969217999999998,-0.15451674599999998,-0.061886990999999995,-0.23107553,1.299251671,2.391722178,-1.887291469,-1.717340775,-1.574923637,-1.8604472580000002,-2.831227745,-1.452517929,-2.060792222,-1.576322918,-1466.516614746768 -3830,3830,A225P,0.008288088,-0.062441776,0.013205903,0.009265303,-0.066311541,0.006686353000000001,-0.037760043,0.054336218,0.015350299,0.000488233,-0.125371785,0.012330932,0.014080873,-0.0034789120000000002,0.022009517000000003,-0.009212706,-0.123410375,1.223670094,2.457657378,-2.177931781,-1.7579258880000002,-2.307343948,-2.69355027,-2.539570473,-1.591268326,-3.389874228,-0.418896018,-1452.5412334948778 -3831,3831,A225S,-0.018873985,-0.010810676000000002,0.032625365,-0.021249774,-0.070292569,-0.025566332,-0.079845248,0.042097277999999995,0.052108367,0.023076122,-0.044697473,0.03927969,0.025971038999999998,-0.004677532,-0.037822015,-0.02328008,-0.117305058,1.4567241130000002,2.579772302,-1.377313597,-1.521993439,-1.282395828,-1.112515625,-1.5949427569999999,-1.3747203369999998,-2.6919811730000003,-0.971199368,-1459.2155756680295 -3832,3832,A225R,-0.040886043999999996,-0.048941272,-0.022352569,-0.020345929,-0.074905372,0.00960336,-0.07475165,-0.007020436999999999,-0.004754494000000001,0.016092866,-0.113975409,-0.00977957,-0.034925568,-0.021663825,-0.019028032,-0.037499945,-0.112310798,1.232750588,2.504239626,-2.7791266739999996,-3.120920845,-2.36272728,-2.980047569,-3.641244705,-1.79069297,-2.8590896530000003,-1.548018353,-1456.1034474596381 -3833,3833,A225T,-0.017775801,-0.12434318,-0.041495997,-0.044757270999999994,-0.144877326,0.014014756000000001,-0.047225048,0.011673447,0.027018551000000002,-0.070970657,-0.177715703,-0.038408948,-0.044583045,-0.032585052,-0.05692948900000001,-0.084233226,-0.205521425,1.347373481,2.2838973069999997,-1.7287782680000001,-1.656881676,-1.613850487,-1.7497052309999999,-1.7448476030000002,-1.878606346,-1.49824478,-1.674361189,-1462.755051997956 -3834,3834,A225W,-0.027560495,-0.017800176,-0.022851985,-0.022187828,-0.17869479300000002,-0.004249681,-0.090666174,0.035545185,0.10317656300000001,0.06284732400000001,-0.098447676,0.053126828,-0.098830797,0.013340668,-0.057716324000000006,-0.16709210300000002,-0.190297482,1.4116154459999999,2.216937685,-7.528216719,-7.486145812999999,-7.6686252370000005,-7.35643013,-8.133568207,-6.9963142089999995,-7.290576706,-6.501824432,-1463.7744933632202 -3835,3835,A225V,-0.037921393,-0.103804194,-0.0066078000000000005,-0.0033735109999999996,-0.062278785,0.025120853999999998,-0.036165072,-0.039677713999999996,0.008304811,-0.009016841999999999,-0.198591545,0.032793439,-0.046009037999999995,1.25e-05,-0.006759522,-0.014381926000000001,-0.110175644,1.2700313540000001,2.57458469,-3.24142946,-2.8649228669999998,-3.127967552,-3.4420184860000003,-3.7862282260000004,-2.98601017,-4.076565566,-2.8482612919999997,-1464.0975681263953 -3836,3836,A225Y,-0.065546067,-0.051310630999999995,0.057600605,0.004113691,-0.11189530800000001,0.069445915,-0.141781051,0.010688917,0.13789556,0.025349682000000002,-0.127970943,0.121557728,-0.006356518,-0.066054815,0.074282196,-0.027352427999999998,-0.196438188,1.21964132,2.419470378,-5.048541177,-4.907087624,-4.985202652,-4.908190796,-6.047012924,-4.395211891000001,-5.191748705,-3.511729462,-1458.6523925364017 -3837,3837,G226A,-0.02805829,-0.008594361,-0.042628081,-0.012893183999999999,-0.474043585,0.017153184,-0.061509053,0.005392473,-0.0008197969999999999,-0.017220322,3.16e-05,-0.047420372,-0.037835789,-0.017984188,-0.007802179,-0.375837326,-0.5722498429999999,1.370338457,1.85427305,-4.512396277,-4.535204086,-4.306642883,-4.881706207,-4.999916077,-3.8385121310000003,-4.623638332,-2.5004067819999998,-1463.6589096761309 -3838,3838,G226C,0.035869467,0.017077352,-0.044959525,0.015524891,-0.89099476,-0.001515506,0.054589501,0.017149433000000002,-0.011385761000000001,-0.024339687000000002,0.05849439,-0.08295699599999999,-0.006962053,-0.047871215,0.078920997,-0.710726511,-1.0712630090000002,1.06899582,1.4958045830000002,-7.252169215,-6.894107636,-7.4839680710000005,-8.181685349,-7.275459587,-6.425625435,-7.821726066,-5.5750201960000005,-1464.7888930756599 -3839,3839,G226E,0.010656361000000001,0.081637855,-0.005545491,0.031012842000000002,-0.084602038,0.014853399,0.05660521599999999,-0.035292495,0.054098898,0.049086527000000005,0.11418918300000001,-0.05462546099999999,0.04353448,-0.011447423,0.073473106,-0.125306422,-0.043897654,1.310944878,2.168496629,-4.419818418999999,-3.53692765,-4.866738403,-5.543896584,-4.694132568000001,-3.457396889,-4.410608713,-1.7928719430000002,-1455.7535404544324 -3840,3840,G226D,-0.001510372,0.007327787,-0.000857558,0.03638795,0.012588812,-0.003148563,0.02769337,-0.030714112999999998,0.016805444,0.01672662,-0.002071046,-0.014987226000000001,0.013272111000000001,0.008895711,0.063880188,-0.005611049,0.030788672000000003,1.2976643,2.624384642,-2.316870998,-1.888723701,-2.40872509,-2.7877172160000003,-2.342844711,-2.156344269,-2.49368057,-0.721205249,-1455.6393291922286 -3841,3841,G226F,0.034473617000000005,0.026400036,0.023914217999999998,0.00819226,-1.399590085,-0.017545441999999998,0.042021437,0.026925797,-0.067609455,0.02307128,0.029728792,0.039856255,0.00797218,0.045698359,-0.02931384,-1.530511788,-1.268668382,0.33883221799999996,1.304335829,-8.006319984,-7.711168953,-7.644680107,-8.704994492,-9.071811653,-6.898944717000001,-6.592626961000001,-5.321523658,-1463.1968242372386 -3842,3842,G226I,-0.048287647999999996,-0.024780552999999997,-0.445642384,-1.83792246,-2.3224547269999998,0.01028465,-0.082603049,-0.013972247,-0.135725275,-0.060524573,0.010963468,-0.259115844,-0.632168924,-1.990930537,-1.6849143819999999,-2.120968565,-2.5239408880000003,1.82469744,0.814229192,-8.049840837,-7.522062531,-8.316318092000001,-8.482666344,-8.651759941,-7.276397277999999,-7.016258183,-5.423042743,-1463.442042994313 -3843,3843,G226H,-0.045574919000000005,0.006194538,-0.056825182,-0.002253544,-0.082656357,-0.008806224,-0.04243418400000001,-0.048715654000000004,0.05835067,0.014920213,-0.002531138,-0.068281532,-0.045368832000000005,-0.027263767,0.022756679,-0.064943743,-0.100368971,1.381689683,2.4442826109999998,-5.211127379,-4.786181442,-4.965749077,-6.075291275,-6.2903984070000005,-3.9380166930000002,-4.555310961,-3.557677144,-1455.1014256891795 -3844,3844,G226K,-0.048999945999999996,-0.013593891,-0.053575552,-0.014748637,-0.013250524,-0.027783641,0.009669005999999999,-0.10766889800000001,-0.292269182,-0.039045781,0.011857999,-0.08906010199999999,-0.018091002,-0.048995054,0.01949778,-0.136923147,0.11042209900000001,1.508442457,2.246936704,-5.646548543,-4.679388321,-5.883714485,-6.885149879,-6.371074875,-4.413415154,-5.855281364,-2.8634250519999997,-1453.9021117552184 -3845,3845,G226M,-0.026654239,-0.014913383,-0.031927095,0.000981908,-1.588387768,-0.02007503,-0.031595765,-0.021712712000000002,-0.09433259,-0.011836813,-0.017989953,-0.037746581,-0.026107609,-0.006273919,0.008237734,-1.138073793,-2.0387017430000003,0.768026743,1.353773902,-9.601171872,-8.837311118999999,-9.347448425,-10.64593247,-10.194813499999999,-8.980353844,-9.027558469,-7.580752578999999,-1463.4428431214765 -3846,3846,G226L,-0.024114795,0.024781845,-0.038626556,-0.10156713099999999,-1.89747051,0.034083142999999996,-0.028336232000000003,-0.019893357,0.023011412000000002,0.013687923999999999,0.035875765,-0.07616727,-0.0010858410000000001,-0.048730841,-0.15440342099999999,-1.807331552,-1.987609468,0.90461726,1.3154172690000001,-7.574734381,-6.7157064129999995,-7.389773368999999,-8.160457016,-8.588859001,-7.0188761060000004,-6.485994681,-3.723148487,-1459.541442034766 -3847,3847,G226N,-0.054262095999999996,-0.031425987,-0.033606435,0.019276097,-0.127757168,-0.055398385999999994,-0.013601084,-0.09492310699999999,-0.013304963000000001,0.012271216000000001,-0.07512319,-0.039864823,-0.027348047,0.028072395,0.010479799,-0.06811379,-0.187400546,1.3251653490000002,2.451458733,-3.3642391910000002,-3.001116287,-2.881685814,-4.7115084000000005,-3.644910484,-2.581974968,-4.268713261,-2.008772011,-1457.9537193696015 -3848,3848,G226Q,-0.007904064,0.003729653,-0.042252909000000005,0.043681387,-0.17476312800000002,-0.013634443000000001,0.049093704,-0.064901831,0.034445239,0.012555161,-0.005095855,-0.063788099,-0.020717718,0.066289044,0.021073729,-0.156931125,-0.19259513,1.335292827,2.197548525,-5.72221434,-4.595090385,-5.733821892000001,-6.965627434,-6.712464637999999,-4.6040673519999995,-5.35394025,-3.510136159,-1458.7437815153971 -3849,3849,G226P,-0.009819404,-0.014950278999999999,-0.054511883,-0.016321519,-1.5035684390000001,0.027223159,-0.023441224,0.003802417,-0.015233021999999999,-0.021562249,-0.008338308000000001,-0.079119535,-0.029904231,-0.017912513999999997,-0.014730523,-1.579287631,-1.4278492459999998,0.752758189,1.3204454140000002,-7.323920963,-7.639528946,-7.497563339,-7.601591553,-7.941372078,-5.939548897000001,-6.775898057999999,-4.017059638,-1452.8637902722694 -3850,3850,G226S,-0.0035022609999999996,0.015074522,-0.038332658,-0.014338116000000001,-0.060375297,0.009052911,-0.023576791,0.01657227,0.030249729,0.025001329,0.005147714,-0.039071832,-0.037593483999999996,-0.021507017000000003,-0.007169215,-0.05512159,-0.065629004,1.392357865,2.486617971,-3.297024084,-3.309308258,-3.275399559,-3.914904922,-3.0358373260000002,-2.949670357,-4.184662327,-2.211067685,-1460.0782414595596 -3851,3851,G226R,0.023698355,0.01679643,-0.014131283,-0.0028417359999999997,-0.160583026,-0.03691833,0.01552629,0.03187042,-0.05884279,-0.007989091,0.041581951,-0.056470299,0.028207733999999998,-0.026471572999999998,0.020788101,-0.188644649,-0.132521403,1.469607535,2.169485859,-5.516256796,-4.734888077,-5.770504234,-6.416279892,-6.222399574,-4.437212204,-5.466075295,-3.354608817,-1452.4653226183727 -3852,3852,G226T,-0.002206326,0.003734652,-0.030094608,0.003821777,-0.033124862000000005,-0.019254309,-0.023206922999999997,0.018794272,-0.062733604,0.008935643,-0.0014663389999999999,-0.018085349,-0.042103866,-0.013279501,0.020923054,-0.043562055999999995,-0.022687667,1.4118036330000001,2.5506220490000002,-3.472849811,-3.03690741,-3.773463074,-4.113892174,-3.395925255,-3.044061142,-4.665947301,-2.270424481,-1463.2044675755315 -3853,3853,G226W,-0.028769767,0.067235348,-0.008073909,-0.080928001,-1.6450957430000002,0.093826928,0.0025836220000000003,-0.060123156,-0.062176459,0.047387577,0.087083119,0.016501294,-0.032649111,-0.004133508,-0.15772249300000002,-1.7582816680000002,-1.5319098169999998,0.6182098570000001,1.305969224,-8.481391104,-7.580779137,-8.516111648999999,-9.605213219,-9.217799141,-7.487052376,-7.682862413,-5.829208481,-1463.7614465397783 -3854,3854,G226V,-0.020969047,-0.010163548,-0.071702969,-1.4359457290000002,-2.483838409,0.024021783999999997,-0.008415799,-0.033522295,-0.015151343999999999,-0.027966539,0.0076394440000000004,-0.145080286,0.0016743489999999999,-1.24033601,-1.631555448,-2.207646741,-2.760030076,2.324857677,1.4806199740000001,-7.241664972000001,-6.770716202000001,-7.769955199999999,-7.547092834,-7.889609901,-6.230950722,-6.50040679,-4.624450349,-1464.6075900439173 -3855,3855,G226Y,-0.041627339,0.07340824,-0.006023717,0.005454194,-1.292676546,0.035901733,0.027611065,-0.110865743,0.009028154,0.048667668,0.098148811,-0.051107792,0.039060357999999996,0.072394721,-0.061486333,-1.1619615079999999,-1.423391584,0.547229362,1.3284864,-7.321787129,-6.930771194,-7.39348912,-8.169059464,-8.195932953,-5.919682915,-6.696968619,-3.626706397,-1459.8291664300486 -3856,3856,W227A,-0.047163357999999996,-0.054309790999999996,-0.528130314,-1.902446588,-2.410115861,0.002412776,-0.066254225,-0.02807249,-0.00578764,-0.09404905,-0.014570531999999999,-0.42170382,-0.6345568079999999,-2.0510341640000003,-1.753859012,-2.659829754,-2.160401967,1.512285839,0.7055132279999999,-8.749722006,-6.350812096,-11.92763999,-6.505862175,-8.602806091,-10.36148968,-5.185798733,-1.447156194,-1449.7537181400694 -3857,3857,W227C,-0.040011906,-0.15387434,-1.444023789,-2.277929629,-2.601610509,0.028663967999999998,-0.037310162,-0.042713649000000006,0.038556913,-0.073734023,-0.234014657,-1.52344397,-1.3646036069999998,-2.385730945,-2.1701283119999997,-2.430255105,-2.772965912,0.69745505,0.032924532,-10.45614405,-8.840139519,-13.39540939,-8.21285157,-9.891450417,-11.94086938,-7.479619059,-5.837160653,-1453.212203599047 -3858,3858,W227E,-0.067131705,-1.326228142,-2.115266861,-2.633820115,-2.874335284,-0.0007340889999999999,-0.067666084,-0.066597325,0.040218174,-1.274348821,-1.378107463,-2.178138719,-2.052395003,-2.961244448,-2.306395781,-2.704738612,-3.043931955,0.133360591,-0.7830992240000001,-12.66754355,-10.06290546,-16.13431291,-10.46113841,-12.61191255,-14.06744842,-8.729899453,-5.767169502000001,-1447.5807146900333 -3859,3859,W227D,-0.052516707999999995,-1.175514232,-2.696327174,-2.825804803,-2.779304338,0.004722863,-0.08643041800000001,-0.018602998,0.064698208,-1.1511329890000002,-1.199895474,-2.485047579,-2.9076067689999996,-2.569183304,-3.0824263010000004,-2.914737459,-2.643871216,0.129055662,-0.721305704,-11.16212465,-8.867377159,-13.51814839,-9.096855292999999,-11.32721093,-13.00103146,-7.680339245,-5.6909617379999995,-1443.68766931165 -3860,3860,W227G,-0.08444311300000001,-0.054982210999999996,-1.4654331809999999,-2.2373264180000003,-2.958552135,0.0015584770000000002,-0.072234613,-0.096651612,-0.024340168,-0.019363104,-0.09060131699999999,-1.38151678,-1.549349581,-2.144878451,-2.329774385,-2.717676388,-3.199427881,0.88235344,0.075050397,-11.76640475,-8.953498878,-14.83887833,-9.395959297000001,-11.54829469,-14.09539256,-8.130351702999999,-5.480871175,-1443.6045147981495 -3861,3861,W227F,-0.0035534140000000004,0.036031292,-0.033449549,-0.048965037999999995,-0.845939091,-0.019739182,0.038371537000000004,-0.045478365,0.02302182,-0.001757668,0.073820252,-0.034831952,-0.032067146,-0.08267582400000001,-0.015254252,-0.692388615,-0.999489567,1.211021003,1.5593081469999999,-7.694531615,-5.918701134,-11.14873684,-6.565628654,-6.8721570210000005,-7.967434425,-5.7505161,-3.7634479410000004,-1455.796618131455 -3862,3862,W227I,-0.062659166,-0.256688769,-1.549722425,-2.609369057,-2.4748229630000003,0.015451241000000001,-0.016284485,-0.10903384599999999,-0.063428035,-0.180457074,-0.33292046399999997,-1.697302348,-1.4021425019999998,-2.480408077,-2.7383300360000002,-2.348840978,-2.600804947,0.9996864540000001,0.013407163,-10.21222814,-8.726114577999999,-13.32373914,-9.132508682000001,-9.424162949,-10.45461537,-7.3617971529999995,-1.989329832,-1456.9843919915147 -3863,3863,W227H,-0.04637097900000001,-0.026141255,-0.969336917,-2.262726132,-2.7369220089999997,0.019503267,-0.057128240999999996,-0.035613716000000004,-0.057202917,-0.009049164,-0.043233345,-0.864979948,-1.073693886,-2.2043881780000003,-2.321064085,-2.549942333,-2.923901685,1.881342386,0.6969242440000001,-11.7201346,-9.438374062000001,-15.84491682,-9.273831696,-11.24592738,-12.79762305,-9.290488647,-6.802986395,-1453.9960562461056 -3864,3864,W227K,-0.037043001,-1.471868894,-2.325454961,-2.255962585,-2.859977118,-0.007116854000000001,-0.023414056000000003,-0.050671945999999995,-0.05430162,-1.55767317,-1.386064618,-2.268338469,-2.382571452,-2.352474194,-2.159450976,-2.999058345,-2.720895891,-0.005323496,-0.9825087029999999,-12.10586356,-9.57906134,-15.05113855,-10.20826182,-12.51061022,-13.18024586,-8.25227111,-5.672781251,-1453.165151678957 -3865,3865,W227M,-0.026012373,0.016057956,-0.11031298,-1.76822655,-2.730242755,-0.034871807000000005,-0.060019227,0.007994481,0.062069125999999995,0.006674494,0.025441417999999997,-0.159248914,-0.061377046,-1.541060993,-1.9953921069999998,-2.699528505,-2.760957005,1.081009437,0.737911742,-11.07819212,-9.718278182999999,-14.46238187,-9.167197685,-10.37966915,-11.66343374,-7.053809461,-4.217516955,-1457.260220934637 -3866,3866,W227L,-0.037928803,-0.598327783,-2.0707466390000002,-2.386417219,-3.214010768,0.030487862,-0.041082403999999996,-0.034775201,-0.023291243,-0.588438196,-0.608217369,-2.216433922,-1.925059355,-2.4766609059999998,-2.296173532,-3.123245056,-3.3047764789999996,0.843835647,-0.397234795,-8.963415829,-7.2226299439999995,-11.71113733,-7.702530777000001,-8.295966629,-9.884814468,-6.149481142000001,-2.836913527,-1455.0201311465353 -3867,3867,W227N,0.015379357,-1.227838038,-2.627131956,-2.606094587,-2.4715484930000002,0.00521904,-0.01679854,0.04755725400000001,0.014100014,-1.019520002,-1.436156073,-2.462579061,-2.7916848510000003,-2.546714786,-2.6654743869999997,-2.4151476869999997,-2.5279492980000002,0.45948966399999996,-0.64814349,-13.08268429,-10.35125268,-15.57599986,-10.69797279,-13.31829711,-15.46989901,-9.854672592,-7.321889477,-1448.8860341222025 -3868,3868,W227Q,-0.035924184,-1.027905073,-2.0845003930000003,-2.184982048,-2.740541574,-0.001838448,-0.065097527,-0.006750841,0.066486328,-1.1027656909999999,-0.953044455,-2.1936422319999997,-1.9753585530000002,-2.15283922,-2.217124875,-2.623332112,-2.8577510360000002,0.15023451,-0.6905365590000001,-12.87795307,-10.52295752,-15.66330035,-10.96900449,-13.52001027,-13.71449273,-9.279431646,-6.66516427,-1453.0430465945974 -3869,3869,W227P,-0.047805659,-1.7244401969999998,-2.1673092030000003,-2.44252917,-3.5768926239999996,-0.013242971000000001,-0.060834267000000004,-0.03477705,-0.13185349400000002,-1.819835536,-1.6290448569999998,-2.00762209,-2.326996315,-2.34703032,-2.53802802,-3.6925844760000004,-3.461200771,-0.232599361,-1.11399797,-12.77688132,-10.23978833,-15.77915876,-10.63560801,-13.30776341,-13.92208809,-8.144402863,-4.822564772,-1448.5224709040485 -3870,3870,W227S,-0.055388977,-0.042426411,-1.055911735,-2.285489605,-3.230124757,0.017154039,-0.05898078599999999,-0.051797168,-0.014345718,-0.066262712,-0.01859011,-0.837305693,-1.274517776,-2.266324697,-2.304654513,-3.51496884,-2.9452806739999997,1.7399079430000002,0.596421914,-10.37615052,-8.173360168,-12.73343616,-7.5462295610000005,-10.55875982,-12.86896691,-7.1572535,-3.0928075789999996,-1448.4203361128457 -3871,3871,W227R,-0.062827882,-1.4570845159999999,-2.071461297,-2.585293772,-2.587686553,0.02215222,-0.053707065,-0.07194869799999999,-0.004433616,-1.4037141819999999,-1.51045485,-2.132604302,-2.010318291,-2.760808071,-2.409779472,-2.667029533,-2.508343572,0.157776742,-0.862477534,-11.21733548,-9.086990692,-13.78438659,-9.17543618,-11.57565248,-12.46421144,-8.321001857,-5.865106355,-1450.6875005699694 -3872,3872,W227T,-0.057075614000000004,-0.02174628,-1.133980669,-2.343091463,-2.9471059960000003,0.076552392,-0.043108952,-0.071042276,0.064523816,-0.031754459,-0.011738101,-1.019316074,-1.248645264,-2.148774778,-2.537408148,-2.649230893,-3.244981099,2.033591494,0.751278268,-10.04969238,-7.627598534,-12.86571387,-7.803569435,-10.35474218,-11.59683789,-7.26029241,-1.298083407,-1453.868418443948 -3873,3873,W227V,-0.09485918300000001,-0.10501336800000001,-1.496315531,-2.249577294,-3.138425058,0.018926157,-0.101502615,-0.088215751,-0.038217254,-0.062679974,-0.147346762,-1.41489565,-1.5777354119999998,-2.260792209,-2.238362378,-2.958528882,-3.3183212330000003,0.880890257,0.072333904,-8.669829672,-7.087214264,-12.04006367,-7.335103584,-7.824304497000001,-9.062462349,-6.60490433,-0.823204093,-1456.5468533369713 -3874,3874,W227Y,-0.120906119,-0.014422706,-0.032958013,-0.044935314000000004,-2.100840027,-3.16e-05,-0.150033655,-0.091778582,0.005579577,0.052028958,-0.080874369,0.011216606,-0.077132632,0.019530016,-0.109400643,-1.8148311519999998,-2.3868489019999997,0.743221252,1.305462926,-7.571193313999999,-5.681504317999999,-10.23329059,-6.674607315,-7.43728331,-7.829281036,-5.917534932000001,-3.075704734,-1456.7454699683003 -3875,3875,F228A,0.034819101,0.10482980300000001,0.038322882,-0.045568097,-0.705757337,-0.098981239,0.009592467,0.060045734,-0.040639287,0.061577249,0.148082356,0.009433944,0.067211819,-0.06506121200000001,-0.026074982000000003,-0.60266673,-0.808847944,1.045491769,1.513181738,-5.168662502,-5.113226021,-5.295019142,-5.796567574,-4.457975243,-5.1805245289999995,-4.338709645,1.260315839,-1455.0434695081785 -3876,3876,F228C,0.08968447800000001,0.01809077,0.05516087099999999,0.003833366,-1.4227194840000001,-0.133256625,0.055160659,0.124208297,-0.075850467,0.030382628999999998,0.0057989109999999995,0.001175358,0.109146384,-0.039480857,0.047147589000000004,-1.43038452,-1.415054448,0.872519,1.3392848590000002,-7.171091522,-7.3241817860000005,-6.8818971410000005,-6.62861274,-7.164868477000001,-7.855897468999999,-7.465080819,-3.121832967,-1458.9500913196243 -3877,3877,F228E,0.007750809,-0.0052450280000000005,-0.0007574519999999999,-1.336517625,-2.6497394169999997,-0.097190971,0.017515563,-0.002013945,-0.11044670300000001,-0.000300862,-0.010189194,-0.017984364,0.016469461,-0.999541254,-1.673493996,-2.754895612,-2.544583222,0.7831339070000001,0.76112441,-5.09736897,-4.414539215,-5.941707732999999,-6.213641182000001,-3.8486754530000002,-5.068281265,-3.467671453,1.5606969,-1447.6936490838416 -3878,3878,F228D,-0.024903281,0.062555582,-0.649745724,-2.314775154,-2.364827307,-0.09928765099999999,-0.055121671,0.00531511,0.037109206,0.059384499,0.065726664,-0.415136341,-0.8843551070000001,-2.152794341,-2.476755967,-2.226907461,-2.502747153,1.390829997,0.6532372,-6.149703581,-5.375492508,-6.9716711270000005,-6.197008469,-5.752258682000001,-6.45208712,-4.353363582,0.185527642,-1446.675089939963 -3879,3879,F228G,0.063027426,0.068428654,0.061150803,-0.467575016,-2.117396431,-0.099691056,0.040606336,0.085448516,-0.071441785,0.05422977599999999,0.082627532,0.030431014,0.09187059199999999,-0.260459331,-0.6746907,-1.954708506,-2.280084355,1.270993628,1.333423407,-5.954611449,-6.549204926,-6.4892449039999995,-4.585500549,-4.826127716,-7.322979149,-4.12292313,-0.11893282699999999,-1454.8022426995449 -3880,3880,F228I,-0.035738797999999995,0.09555123300000001,0.059271792999999996,-0.10089648,-1.514573075,-0.033208732000000005,-0.025844499,-0.045633097000000004,-0.15001735300000002,0.189553257,0.001549209,0.07886674099999999,0.039676845,-0.01371353,-0.188079429,-0.834314893,-2.1948312569999997,0.73612221,1.3802270540000001,-3.871866818,-3.604431343,-4.094313042,-4.648792679,-3.370314613,-3.641482414,-3.908425378,1.516578741,-1460.9902398856357 -3881,3881,F228H,0.054301557,0.059061415,0.027849323999999998,-0.055433891,-0.9297338270000001,-0.10441484300000001,0.031796199,0.076806915,-0.074852487,0.08924800000000001,0.028874828999999998,0.014855055,0.040843592000000005,-0.087319198,-0.023548583999999997,-0.688445443,-1.171022211,1.088151176,1.506760747,-3.869861568,-4.963229378,-3.5927679980000002,-2.7115910189999997,-3.68473658,-4.396982864,-4.654227133,-0.108022492,-1456.9964220197871 -3882,3882,F228K,0.08967324,0.056720277,-0.063812484,-0.122202633,-1.376374769,-0.08840174599999999,0.072002464,0.107344016,-0.17296655100000002,0.075568303,0.037872251,-0.14149214599999999,0.013867178999999999,-0.072970171,-0.171435095,-0.925234542,-1.827514995,1.219185529,1.489159541,-4.066990816000001,-4.38103241,-4.525627075,-4.1180619510000005,-4.174996558999999,-3.1352360839999998,-3.2426862819999998,2.137464243,-1463.700180189684 -3883,3883,F228M,0.005584345,0.044304052000000003,0.015649041000000002,-0.072049924,-0.167753136,-0.151367284,0.0020067279999999997,0.009161961,-0.118519518,0.047811779000000006,0.040796324,0.021293647000000002,0.010004434,-0.138107277,-0.00599257,-0.184574143,-0.150932129,1.331223188,2.041398221,-4.476601221,-4.976921379,-4.183011505,-4.049390121,-4.073266037,-5.100417061,-4.237412471,-0.8342781340000001,-1462.96637764154 -3884,3884,F228L,0.016878473,0.067237508,0.044833205,-0.017086541,-1.38825315,-0.057057705,-0.014523362,0.048280308,-0.060330699,0.057245868,0.077229147,0.041523689,0.048142721,-0.070004229,0.035831148,-1.468747165,-1.307759135,0.98882085,1.348733371,-3.421797849,-3.9119002910000003,-2.5376745990000003,-3.3273038789999996,-3.6587394410000003,-3.673371033,-4.238509895,0.8944283059999999,-1462.2390198898502 -3885,3885,F228N,-0.098818831,0.1554642,0.082388889,-0.043138267,-2.058817623,-0.077984931,-0.15331145599999998,-0.044326205,0.003440215,0.240461662,0.070466737,0.152238611,0.012539167,0.019575036,-0.10585157,-1.87408202,-2.243553226,0.620598587,1.300176463,-5.324353757,-5.43412072,-5.432065063,-4.536406723,-5.625005951,-5.594170326,-5.258665037,-0.081957632,-1457.7553060674109 -3886,3886,F228Q,0.083771655,0.144144313,0.065153763,-0.069929773,-1.501144034,-0.083237594,0.066237532,0.10130577800000001,-0.106043415,0.104261359,0.184027267,0.086501066,0.043806459000000006,-0.041672925,-0.09818662,-1.5856080609999998,-1.416680006,0.700612841,1.3170379190000001,-4.183064699,-4.78273922,-4.395836441,-3.9499811780000003,-3.77038089,-4.016385765,-3.0290243639999996,1.50933927,-1458.0466327769682 -3887,3887,F228P,0.013825108000000001,-0.712075188,-2.204574912,-2.550107461,-2.9293356910000004,-0.060439926,-0.001243225,0.02889344,-0.0036822609999999996,-0.626285973,-0.7978644020000001,-2.410693656,-1.9984561680000001,-2.4951391419999998,-2.60507578,-2.775306745,-3.083364636,0.375239692,-0.528984935,-5.770727083,-7.182700287,-4.007586029,-6.380903625,-4.313259193,-6.969186279,-4.857002713,1.172139024,-1455.6027040290646 -3888,3888,F228S,0.033219423,0.092614051,0.049866852999999996,-0.034156986,-1.232204024,-0.09031324199999999,0.035132136,0.03130671,-0.037012462,0.068632179,0.116595923,0.035631919,0.064101786,-0.07103567200000001,0.002721701,-1.093353346,-1.371054701,1.008833687,1.39886342,-3.487704623,-3.6733709489999997,-3.4820455089999998,-2.858377022,-3.65195256,-3.7727770769999998,-3.2485395039999996,1.208492804,-1455.333502676338 -3889,3889,F228R,0.035772611,0.080506595,0.051593198,-0.023338256,-1.14201242,-0.070295346,0.031534207,0.040011015,-0.076658189,0.102148642,0.058864547,0.061632592,0.041553803,-0.051694437,0.005017925,-1.169159546,-1.1148652940000001,0.864773419,1.3590320230000001,-4.7086980160000005,-5.316103622,-4.486409752,-4.138878761,-4.515474533,-5.086623413,-2.411800269,2.6686776130000003,-1460.7989422380924 -3890,3890,F228T,0.040537346,0.019403695,0.004287443,-0.080922555,-1.022036606,-0.103798664,0.021386807,0.059687885,-0.08235759,-0.033483714,0.072291103,0.00657039,0.002004495,-0.13765627,-0.024188839,-1.040710192,-1.00336302,1.138127468,1.4355649080000001,-3.799296155,-3.161730927,-3.719481552,-4.184201584,-4.234009308,-3.6970574039999997,-2.8165484839999997,2.449725001,-1457.4911507139914 -3891,3891,F228W,0.04264328,0.004783932,0.018125335,-0.04195293,-0.20135755800000002,-0.07806152200000001,0.028096977999999998,0.057189580999999996,-0.0062953869999999995,-0.020114455,0.029682318,0.0033666409999999996,0.032884027999999996,-0.041478205,-0.042427654,-0.18450714899999998,-0.218207967,1.583149769,2.310440244,-4.835200641,-5.1613421939999995,-4.055635605,-4.667095711,-4.736917007,-5.555012688,-5.584854934,-1.092872427,-1458.287049613893 -3892,3892,F228V,-0.0015192,0.071191963,0.044245122000000005,-0.056016408,-0.947842669,-0.092051485,-0.029686123,0.026647723999999998,-0.075979632,0.095450265,0.04693366,0.048900725,0.039589519,-0.06332888099999999,-0.048703934000000004,-0.7373337670000001,-1.1583515709999999,0.9369956159999999,1.442488393,-4.34699781,-4.07201783,-4.574214615,-4.7294993739999995,-4.00350502,-4.355752213,-4.063435392,2.198252874,-1458.9179777470417 -3893,3893,F228Y,0.083847173,0.059318418,-0.047205919000000006,-0.054358355,0.082612214,-0.08908438699999999,0.09536891800000001,0.072325427,-0.076910254,-0.008512641,0.12714947599999998,-0.041512901,-0.052898935999999994,-0.08735501400000001,-0.021361696,0.031694729,0.133529698,1.209169271,2.751116301,-0.9576026209999999,-1.002206535,-0.9138741459999999,-0.859307571,-0.9619984659999999,-1.050626389,-2.5550118719999997,-0.956348581,-1457.4934035399929 -3894,3894,I229A,-0.069410175,-0.009194266999999999,-0.022617725,-0.498010987,-2.164150476,-0.047322728,-0.058249232000000005,-0.080571118,-0.025520719,0.044674723,-0.063063257,0.059230841,-0.10446629,-0.140983006,-0.855038968,-2.051746359,-2.276554592,0.986912628,1.302322145,-8.416061873,-6.684182381,-8.170437576,-8.217985657,-7.841819762999999,-11.16588399,-5.843884611,-1.729619459,-1458.2924747280777 -3895,3895,I229C,-0.018434574,-0.038239933,-0.00527992,-0.03924641,-0.26286681300000003,-0.021814132000000003,0.005045292,-0.041914439,0.007929562,-0.022655197999999998,-0.053824668,0.07778862,-0.088348459,-0.01172377,-0.066769049,-0.251743379,-0.273990247,1.203413474,1.873144023,-10.74783069,-9.858151581,-10.27910246,-11.79328159,-9.773461304,-12.03515653,-7.4469440989999995,-3.797866888,-1459.4667118182406 -3896,3896,I229E,-0.118163448,-0.204449049,-1.606157646,-2.408972436,-2.863877939,-0.00018130599999999997,-0.093616218,-0.14271067699999998,0.010441283,0.00047137199999999996,-0.40936947,-1.5450958940000001,-1.667219398,-2.470514563,-2.347430309,-2.609540769,-3.118215109,0.557465311,0.02243671,-12.00268332,-10.11901456,-12.04317039,-12.14820953,-10.24863245,-15.45438969,-8.45180826,-5.495237653999999,-1453.3276130724698 -3897,3897,I229D,-0.036650925,-0.530136698,-1.819078912,-2.1181931940000003,-2.8901132960000004,-0.031067167000000003,-0.013327668,-0.059974180999999994,-0.012719905,-0.26147631600000004,-0.79879708,-1.8746569780000002,-1.763500845,-2.3229543919999998,-1.913431996,-2.859920608,-2.9203059839999996,1.082465498,-0.048597466,-14.4124682,-12.86251445,-14.51752683,-14.76061289,-12.63306866,-17.28861816,-10.72163131,-9.040801153,-1455.2426663548686 -3898,3898,I229G,-0.084474875,-0.045300644,-1.45001766,-2.321530954,-2.7583099339999997,-0.048092622,-0.063402845,-0.105546904,-0.04973572,0.01285798,-0.10345926800000001,-1.38423598,-1.51579934,-2.272992663,-2.370069244,-2.7685661930000003,-2.748053674,0.656482615,0.05557492,-12.37320936,-9.398242386,-12.37932755,-13.29583441,-11.61978018,-15.17286228,-7.923392099,-4.333446926000001,-1444.0276597300544 -3899,3899,I229F,-0.11250589400000001,-0.05666062,-0.030493907,-1.482905359,-2.078295963,-0.101889922,-0.099795331,-0.125216456,-0.042873300999999996,0.04613657400000001,-0.159457813,0.030374442999999998,-0.09136225699999999,-1.210714747,-1.755095971,-2.066439725,-2.090152201,2.340730752,1.5516690640000002,-9.670601863,-8.691327583,-7.817211334,-11.37656223,-9.782511688,-10.68539648,-6.00651842,-1.495245675,-1455.6425520833582 -3900,3900,I229H,-0.082700661,-0.032096909,-1.295386883,-2.106377184,-2.982101441,-0.011462223999999998,-0.041880875,-0.12352044699999999,-0.02844013,-0.011823811000000002,-0.052370006,-1.258517678,-1.332256087,-2.1169895569999997,-2.09576481,-2.9549857680000002,-3.009217113,0.7347734840000001,0.085176321,-14.97365578,-12.65760128,-14.02125831,-15.33147475,-14.20916115,-18.64878344,-9.505399031,-6.0201802120000005,-1449.6521760802716 -3901,3901,I229K,-0.05980169900000001,-0.031431826,-1.498162846,-2.30070772,-3.030689638,-0.046516218,-0.022964226,-0.096639171,-0.086822119,0.0005644480000000001,-0.0634281,-1.33702612,-1.659299572,-2.341626035,-2.259789405,-2.9243497410000003,-3.137029535,0.628572103,0.06431168,-14.24863385,-12.90801746,-13.65958093,-14.39900317,-12.33425845,-17.9423092,-10.72610791,-9.063402344,-1451.0450370297767 -3902,3902,I229M,-0.034686191,-0.002498985,-0.006363678,-0.017867238,-0.607769943,-0.054066044,-0.005625576,-0.063746806,-0.049273679,0.045896427999999996,-0.050894398,0.065103162,-0.077830517,0.032555315,-0.06828979,-0.46860607,-0.746933816,0.680750987,1.450953409,-7.612678645,-7.719456772000001,-7.133450409,-9.892551597999999,-7.925485435,-5.392449012999999,-6.642132025,-3.341766762,-1461.2276748162694 -3903,3903,I229L,-0.072972947,-0.023108798,-0.031415698,-0.023144424,-1.216477581,-0.100695239,-0.064336139,-0.081609755,-0.04913736900000001,0.026071916,-0.072289511,0.053992976,-0.116824371,0.058049131,-0.104337979,-1.140424698,-1.292530463,0.658855608,1.338664433,-6.81619496,-6.270641006,-5.879656075,-8.929904037,-6.016914757,-6.983858925,-5.272553434,-1.092207017,-1459.0134785738774 -3904,3904,I229N,-0.083550736,-0.051992474000000004,-0.81172786,-2.243190302,-2.6856840139999996,-0.001593391,-0.057831310999999996,-0.10927016,-0.004905019,-0.008567874,-0.095417073,-0.476507721,-1.146947998,-2.305016377,-2.181364227,-2.74507258,-2.626295447,1.362198087,0.565428192,-13.80432748,-12.07785767,-14.78292802,-14.09083838,-12.32167987,-15.74833346,-9.905708836,-6.6827684110000005,-1453.1019362052903 -3905,3905,I229Q,-0.059360261,0.006274115,-1.3743459930000002,-2.3197786469999997,-2.9084872710000003,-0.013432571,-0.035474562,-0.08324596,-0.06129640099999999,-0.001026605,0.013574835,-1.300765153,-1.4479268330000001,-2.210389555,-2.429167739,-2.872294507,-2.9446800339999997,0.637943334,0.06939721900000001,-14.12067794,-12.755091,-14.0205646,-14.24484502,-11.79798397,-17.78490512,-10.72610791,-9.063402344,-1449.7302843313664 -3906,3906,I229P,-0.08172216,-1.610386677,-2.262329793,-2.334286207,-2.9799665060000002,-0.014989348000000001,-0.070993975,-0.092450345,-0.106152031,-1.733628547,-1.4871448059999999,-2.262266235,-2.26239335,-2.0067947619999997,-2.661777651,-2.70346182,-3.256471191,-0.160249955,-1.110350261,-13.78547602,-12.33307677,-13.796525599999999,-14.21220858,-12.72580354,-15.85976559,-9.560169155,-6.410978878,-1455.3506755181588 -3907,3907,I229S,-0.07371826,-0.036303463,-0.407388759,-2.0365659430000003,-3.095345961,-0.014685356,-0.060980944,-0.08645557599999999,-0.055108184000000004,-0.003009297,-0.06959762900000001,-0.256925732,-0.557851786,-1.926341375,-2.14679051,-2.915605261,-3.2750866610000005,1.27897484,0.701574246,-10.05259946,-8.113501747,-11.09416805,-10.87198161,-9.026331032,-11.15701486,-6.461403316,-2.689590051,-1452.3904121792875 -3908,3908,I229R,-0.08818997699999999,-0.15859214300000002,-1.681584515,-2.335897718,-2.89429032,-0.02983625,-0.06344221,-0.112937744,-0.043233282000000005,-0.055508222,-0.261676063,-1.642970694,-1.720198335,-2.249261145,-2.422534291,-2.7148714519999997,-3.073709188,0.7210686740000001,0.006662591,-14.29713226,-12.98181963,-13.76461433,-14.29879346,-12.12302988,-18.31740396,-9.021325447999999,-5.802377582,-1444.2928440603428 -3909,3909,I229T,-0.089289656,-0.021184647,-0.53331329,-1.948994764,-2.658762353,-0.015301061999999999,-0.074858868,-0.10372044400000001,-0.021092378,0.0075328159999999995,-0.04990210900000001,-0.278871639,-0.787754941,-1.765362048,-2.132627479,-2.533722331,-2.783802375,1.3245107059999999,0.7369036720000001,-8.751654924,-7.389862885,-8.416578384,-9.533736725,-8.59171357,-9.826383057000001,-5.978377227999999,-1.92299447,-1455.3684478043579 -3910,3910,I229W,-0.045147097000000004,-0.025102576,-0.844125942,-2.0345341180000003,-2.7491487269999997,-0.011215716,-0.022435188,-0.067859006,-0.069621072,-0.044462812000000004,-0.005742339,-0.672743717,-1.015508166,-2.2184471980000002,-1.8506210369999998,-2.4331941180000003,-3.065103335,1.6925050730000002,0.65505085,-12.86131018,-11.80160159,-11.50875249,-13.2472619,-11.82041119,-15.92852374,-7.877753956,-2.184050546,-1455.616392632015 -3911,3911,I229V,-0.057768862000000004,-0.03558698,-0.021215455,-0.017933436,-0.30258486,-0.033463746,-0.043185639000000005,-0.072352085,-0.07125168400000001,-0.013481006,-0.057692954000000005,0.07801055400000001,-0.12044146300000001,0.045654115,-0.081520987,-0.268185207,-0.336984512,0.840184521,1.627879045,-3.68025253,-3.483888275,-2.8268575439999997,-3.30088932,-3.981686073,-4.807941437,-5.1185753730000005,0.8082562870000001,-1465.1534167472273 -3912,3912,I229Y,-0.059964285,-0.022906887,-0.003197551,-1.574836975,-2.505668973,-0.075255208,-0.03383762,-0.08609095,-0.03263289,0.005723961,-0.051537735,0.077142134,-0.083537235,-1.4169983380000002,-1.732675612,-2.462120042,-2.549217903,0.618889537,0.7050145329999999,-12.20591889,-10.59103956,-10.34467379,-12.83830901,-11.87163364,-15.38393846,-8.466165645,-3.511969808,-1448.935150035657 -3913,3913,A230C,0.07310897,-0.004171958,0.048859207,0.001506142,-0.216393002,-0.053046782,0.009368173,0.13684976699999998,-0.016132043999999998,-0.017617666,0.009273751,0.020522519,0.077195894,-0.022928851,0.025941135,-0.227233328,-0.205552675,1.301847205,1.990501504,-11.00741226,-9.420176544,-11.3167013,-11.21582285,-11.23938133,-11.84497926,-8.591221914,-6.522559779,-1461.2573995338753 -3914,3914,A230E,-0.01785081,-0.938637313,-1.8635617880000002,-2.141555238,-2.6446883409999997,-0.029437271,-0.011906507,-0.023795112,0.108199615,-0.8577856759999999,-1.01948895,-2.069408178,-1.6577153969999998,-2.026454942,-2.256655533,-2.6513689680000003,-2.638007714,0.354799882,-0.59052157,-8.183276454,-7.187504477999999,-8.119523651,-8.266883575,-9.182777183999999,-8.159693382,-6.660476608,-4.655544631000001,-1455.8382903174497 -3915,3915,A230D,-0.05843501,-1.641969546,-2.02874737,-2.2739014330000002,-2.7435611410000003,-0.06765581,-0.063766253,-0.053103766,-0.0028655779999999997,-1.956292058,-1.3276470340000002,-2.15088122,-1.906613519,-2.2328667209999997,-2.3149361440000003,-3.033872006,-2.453250275,-0.68648166,-1.113512379,-10.55394955,-9.299721893,-10.46668332,-10.8273447,-11.70386594,-10.4721319,-8.086664255,-6.03153719,-1458.6323669436388 -3916,3916,A230G,0.025998699,-0.006894561,0.036733964,0.022933474,-0.023878032,-0.045517713,0.019219032,0.032778366,0.015902555,-0.006291191999999999,-0.007497929,0.029334516,0.044133412000000004,-0.004519398,0.050386345,-0.036233859,-0.011522204,1.324008576,2.494239028,-3.022619725,-2.631046188,-3.52214994,-2.592684502,-2.354714676,-4.0125033189999995,-3.1844883439999996,-0.6673508429999999,-1459.8412372786552 -3917,3917,A230F,0.003044142,0.018138504,-0.795527911,-2.128195162,-2.480813267,-0.019336381,0.024659935,-0.018571652,0.042794766,0.015549365,0.020727643,-0.504429139,-1.086626683,-2.177479247,-2.078911076,-2.501363277,-2.460263257,1.507483761,0.650746343,-11.126307699999998,-7.920529327000001,-9.904449295,-11.0034528,-13.911523,-12.89158408,-6.4552787910000005,-3.8655559810000004,-1459.120366203133 -3918,3918,A230I,0.034863112,0.001676746,0.042113699000000004,0.015709083000000002,-1.518781792,0.019535587,0.039806098,0.029920126000000002,0.005619140999999999,-0.061852423,0.065205914,0.013005243,0.071222155,0.010451374,0.020966791999999998,-1.5315428359999999,-1.5060207469999998,0.7248655540000001,1.321320016,-8.037424866,-7.436695922999999,-6.533652779,-7.785264503,-8.762618881,-9.668892242,-6.253143255,-3.764437635,-1456.5048983939923 -3919,3919,A230H,-0.034737835,-0.579205569,-1.9604857009999999,-2.418624129,-2.800238208,0.021204162000000002,-0.037756676,-0.031718993,0.039513781,-0.44106243799999995,-0.7173487,-2.062859405,-1.8581119959999999,-2.211791695,-2.625456563,-2.535675725,-3.0648006910000003,1.10133539,-0.196933048,-11.88315462,-9.425069763,-11.60423812,-11.38770529,-13.46344165,-13.535318300000002,-7.730192914,-4.7787964789999995,-1459.598852451425 -3920,3920,A230K,-0.18703937,-1.195776298,-2.140636528,-2.264271566,-2.432901279,0.009118119000000001,-0.21879432199999999,-0.15528441699999998,0.078420479,-0.997536292,-1.394016304,-2.11640474,-2.1648683159999997,-2.198390241,-2.330152891,-2.522274271,-2.343528287,0.298042207,-0.642985108,-11.46725961,-10.14585313,-10.9941729,-11.76708222,-12.43277838,-11.99641143,-8.348859653,-6.875547631,-1463.0254295058548 -3921,3921,A230M,0.00987137,0.025264624,-3.6700000000000004e-05,-0.009490555999999999,-1.560654907,-0.0053462530000000005,0.024464831,-0.004722092,0.036060762999999996,-0.034914851000000004,0.08544409900000001,-0.089611564,0.08953819800000001,-0.09241581900000001,0.073434707,-1.3789755259999998,-1.7423342869999998,1.013851818,1.361419387,-9.670725401,-8.979123085,-8.973285011,-10.04643431,-10.92424394,-9.430540657,-7.50578437,-6.029131173,-1457.5933248200454 -3922,3922,A230L,-0.004442268,0.009531953000000001,0.029722899,-0.536704787,-1.8930656369999999,-0.040667257000000005,0.01469173,-0.023576265,0.003129215,-0.018531753,0.037595658,0.0013399010000000001,0.058105897000000004,-0.26970183600000003,-0.803707737,-2.02991305,-1.7562182240000002,1.31395131,1.325776552,-8.28114856,-6.228448631,-6.863342979,-8.58206649,-10.39068058,-9.341204117,-6.093341642,-3.850641903,-1456.533792463597 -3923,3923,A230N,0.065169214,-0.592148453,-1.93541351,-2.290927194,-2.741692622,-0.008096096,0.055185824,0.075152603,0.049316755999999996,-0.46623989,-0.7180570159999999,-2.2243101380000003,-1.646516881,-2.607325634,-1.974528754,-2.931209664,-2.55217558,0.501796989,-0.45374916200000004,-11.45653818,-10.63149962,-11.08081659,-11.70185131,-11.68044138,-12.188082000000001,-8.460426617000001,-6.642807821,-1458.5716778663918 -3924,3924,A230Q,-0.023695522000000004,-0.10350028300000001,-1.6575347669999998,-2.053203827,-2.610909165,-0.020708925,-0.051239245999999995,0.0038482029999999997,0.052047864000000006,-0.071348852,-0.135651713,-1.700050487,-1.6150190469999999,-1.8489827769999998,-2.257424877,-2.649988062,-2.5718302680000003,0.7460731820000001,-0.000102915,-11.1032055,-9.470077972,-11.70854729,-11.01872617,-11.6031524,-11.71552365,-8.305837084,-6.47434758,-1458.177317969501 -3925,3925,A230P,-0.014726798000000001,-1.6946270890000001,-2.121499039,-2.362795216,-3.336932346,-0.007311351999999999,-0.013914923000000001,-0.015538673000000001,-0.079101488,-1.8319985369999998,-1.55725564,-2.1442271969999998,-2.09877088,-2.2596364540000002,-2.465953978,-2.981460492,-3.692404199,-0.477596666,-1.128753168,-10.04794205,-9.392321304,-10.02189403,-10.35748496,-10.32660672,-10.14140324,-7.7255789660000005,-5.688545746,-1463.756430672016 -3926,3926,A230S,-0.0030235970000000003,-0.016084651999999998,0.00952864,0.001800725,-1.721756113,-0.00892382,-0.012363881,0.006316688000000001,0.033354575,0.0047309529999999995,-0.036900257,-0.002006527,0.021063807,0.021827495,-0.018226046,-1.7286365190000001,-1.714875706,0.713462158,1.310446077,-6.392997942999999,-6.387666542000001,-6.076708595,-7.00126725,-6.447538292000001,-6.051809036,-6.592293261,-2.46894393,-1459.8901135390624 -3927,3927,A230R,-0.026987875,-0.102298681,-1.510833571,-2.145455837,-2.6212824130000003,-0.035452864,-0.042461235,-0.011514513999999998,0.010826753,-0.06857379799999999,-0.13602356300000001,-1.49444992,-1.527217222,-2.1014802280000002,-2.189431446,-2.772151744,-2.470413081,0.7911024390000001,0.04887163,-11.54919984,-9.209257164,-12.41247314,-11.36251881,-12.29312255,-12.46862756,-7.600294077,-5.607703599999999,-1459.6217295117676 -3928,3928,A230T,-0.037679194,-0.020095778,-1.142326498,-2.040107479,-2.911652176,-0.021789298999999998,-0.045193905,-0.030164482000000003,0.001968283,-0.011047388,-0.029144167999999998,-1.0228320359999998,-1.261820959,-2.062756191,-2.017458766,-2.8985235830000002,-2.924780769,2.0964217609999998,0.813381625,-9.361114528,-8.350548759,-9.115197432999999,-10.38899005,-9.838944298,-9.111892097,-8.253697788,-6.430092654,-1457.432042463217 -3929,3929,A230W,0.087262094,0.044934558,-0.09520053699999999,-1.65611943,-2.481381369,-0.061574624,0.048870066,0.12565412199999998,0.017124752,-0.040404255,0.13027337,-0.125779621,-0.064621453,-1.557528166,-1.7547106940000001,-2.240434139,-2.722328599,1.047581533,0.7301790420000001,-12.60324454,-10.10696928,-12.48599938,-12.94141858,-13.58021128,-13.90162418,-7.4281568039999994,-4.646134273,-1463.7831579665653 -3930,3930,A230V,-0.075575096,-0.012857571000000002,-0.005644093,-0.064019977,-1.723396046,-0.021461276,-0.068913097,-0.082237095,0.038540227999999996,-0.007933062,-0.01778208,-0.015905851000000002,0.004617665,0.035172998,-0.163212951,-1.782947499,-1.6638445919999998,0.716159621,1.307532352,-7.2174384279999995,-6.355203529,-5.98487616,-6.906607704,-8.383994987000001,-8.456509758,-6.179491962999999,-4.2439615580000005,-1458.8567187567241 -3931,3931,A230Y,0.014798192,0.016326603999999998,-0.167497955,-2.33271403,-2.7143281089999998,0.033072957,0.045934892000000005,-0.016338508999999998,0.096786944,0.031352845,0.001300362,-0.121556739,-0.21343917,-1.92781811,-2.73760995,-2.8537621310000003,-2.574894086,0.8689848090000001,0.6699047370000001,-11.97813137,-8.509947296,-11.55051458,-11.53893936,-13.83476137,-14.45649422,-6.183387993999999,-2.796177016,-1449.8685053787194 -3932,3932,D231A,0.02150478,-0.031308565,-0.018840684,0.025798237,-1.4331557590000001,-0.130587506,0.013137976,0.029871582999999997,-0.00188233,-0.003464338,-0.059152792,-0.008024237,-0.029657131,0.020495221,0.031101252000000003,-1.583391389,-1.282920128,0.68585368,1.3158599770000001,-12.52445417,-15.20094563,-10.58945024,-11.99042255,-12.43972858,-12.40172383,-7.876084272000001,-3.005386881,-1421.4327271124348 -3933,3933,D231C,-0.023477007,-0.180688987,-0.039066814,-0.581795958,-1.725629241,-0.10330030400000001,-0.023537287999999996,-0.023416725,-0.01713389,-0.052729613,-0.30864836100000004,-0.050909473,-0.027224154,-0.5728061010000001,-0.590785814,-1.8396615369999998,-1.611596944,1.8371564740000002,1.4644759859999998,-14.36774703,-17.41568373,-12.83874007,-14.67206741,-14.8724793,-12.03976466,-8.124826844,-4.704388938,-1430.8806034368463 -3934,3934,D231E,-0.054703638,-0.007488065,-0.02368147,-0.982891044,-2.05105119,-0.066203257,-0.021451001,-0.087956274,0.033970382,0.06764083900000001,-0.082616968,-0.001116839,-0.046246101,-0.737138582,-1.228643505,-1.64959004,-2.45251234,2.26292779,1.7462975180000002,-7.211638067999999,-10.33676988,-6.194371689,-4.920760361,-7.796875237,-6.80941317,-6.012169144,-3.3217758660000003,-1446.1734111178666 -3935,3935,D231G,-0.031729407,-0.069632209,-0.030286199,-0.9132807820000001,-1.758466787,-0.111285005,-0.016771211,-0.046687602,0.009171964,0.01083364,-0.15009805699999998,0.011554551000000001,-0.07212694900000001,-0.794679073,-1.03188249,-1.9171510680000001,-1.599782505,2.079027688,1.5313506140000002,-11.21315101,-13.44046407,-9.715814697,-10.49424036,-10.50487752,-11.91035838,-6.930495712999999,-2.008089853,-1423.5713975424878 -3936,3936,D231F,-0.09247495900000001,-0.139342899,-0.076766997,-1.731017515,-2.555596064,-0.011034545,-0.083785061,-0.101164857,-0.040296723,-0.072148869,-0.20653692899999998,-0.06765242,-0.085881573,-1.904344325,-1.557690704,-2.7410750680000002,-2.370117059,0.8781032009999999,0.676465318,-17.91769814,-20.85068404,-15.508904500000002,-16.67570716,-19.95324709,-16.59994793,-8.311524423,-4.616693367,-1437.6960434964858 -3937,3937,D231I,-0.034437642000000004,-0.064439119,-0.038726922999999996,-1.137602003,-1.741440104,-0.06807893200000001,-0.008821192,-0.060054092,-0.035785415,0.056551867,-0.18543010399999998,0.027466894,-0.104920739,-1.0280682509999999,-1.247135755,-1.9617090080000001,-1.521171199,2.318185927,1.62336739,-17.41571857,-21.46389272,-15.42449728,-15.98286625,-17.68820477,-16.51913185,-10.91672545,-9.471823037,-1435.0925403810106 -3938,3938,D231H,-0.01461284,-0.12043495300000001,-0.053184487,-0.7180977040000001,-2.0697962519999997,-0.059624782,0.019788431000000002,-0.049014111,0.005902956,0.009621297,-0.25049120199999997,-0.018989685,-0.087379289,-0.6414144039999999,-0.7947810040000001,-2.038450391,-2.1011421130000003,1.7979625959999999,1.39336116,-10.408529,-13.89447209,-6.087576782,-10.72936848,-10.85985939,-10.47136825,-6.793893300000001,-0.09620016,-1449.5953060141765 -3939,3939,D231K,-0.155447312,-0.129983221,-0.053511524000000005,-1.040931808,-2.095655881,-0.060421090999999996,-0.16789385699999998,-0.143000766,-0.035368265,-0.03077692,-0.22918952199999998,0.009376693,-0.116399741,-1.0317025359999998,-1.05016108,-1.935380069,-2.255931692,2.304627579,1.61597149,-17.00357504,-19.94821085,-16.50480152,-16.06061276,-16.78737693,-15.71687314,-10.95133296,-9.66088339,-1441.2902177278884 -3940,3940,D231M,0.09687491699999999,-0.015080801999999999,0.063871564,-1.109071338,-2.377438798,-0.17296055600000002,0.129193136,0.064556697,-0.0032444109999999996,-0.010646899,-0.019514704,-0.002103125,0.129846253,-0.9260689540000001,-1.292073721,-2.628101124,-2.126776471,0.713532692,0.7585691659999999,-17.8868029,-21.40642545,-16.61448894,-16.68018628,-17.65567476,-17.07723906,-10.95133296,-9.66088339,-1435.6690168036148 -3941,3941,D231L,-0.01955362,-0.067638102,-0.026758857999999996,-1.186572977,-1.942197894,-0.07194143900000001,-0.001533806,-0.037573433999999996,0.035970128,0.027952442,-0.163228646,-0.009591146,-0.04392657,-0.995185702,-1.3779602519999998,-2.022248144,-1.862147644,2.249805501,1.56493623,-16.71648513,-20.06024461,-16.06066321,-15.30705621,-16.96542526,-15.18903633,-9.074075826,-6.132198026,-1437.190828726627 -3942,3942,D231N,-0.094655512,-0.115059001,-0.079820668,-0.084419143,-2.118517766,-0.069757351,-0.04023423,-0.149076793,-0.067703729,-0.06645045299999999,-0.163667549,-0.023749651,-0.135891685,-0.055851824,-0.112986461,-1.844521122,-2.39251441,0.8431632440000001,1.310274663,-8.245499789,-10.20744124,-7.047991074,-7.8867011179999995,-8.583340446000001,-7.50202507,-5.640531499,-1.592780632,-1446.2573214895092 -3943,3943,D231Q,0.009296067,-0.006101881,0.054436137999999995,0.04086683,-1.815948013,-0.11526935,-0.0016028079999999998,0.020194942,0.029981455,0.120006322,-0.132210083,0.11226831400000001,-0.0033960390000000004,0.073931046,0.007802613000000001,-1.673858614,-1.9580374109999998,0.7446176959999999,1.314767674,-13.81750317,-17.58630382,-11.99865932,-12.07512873,-14.5897247,-12.83769929,-8.08318493,-4.053220639,-1438.3796710944735 -3944,3944,D231P,-0.025129627,-0.058151699999999994,-0.022263089,-1.3429517219999998,-2.134817462,-0.012285551,-0.008799594,-0.04145966,-0.024651687000000002,0.034701799,-0.151005199,0.015245792,-0.059771969,-1.146608492,-1.539294951,-2.155274534,-2.11436039,2.212031006,1.46114532,-16.61670105,-19.86104309,-14.49206679,-15.70908118,-16.49327897,-16.52803523,-10.95133296,-9.66088339,-1443.7522668722086 -3945,3945,D231S,-0.044879811,-0.066896289,0.001676225,-0.253190316,-1.52339746,-0.066766269,-0.03292163,-0.056837991,0.028071235,0.044880156,-0.178672733,0.040801012000000005,-0.037448563,-0.13627676800000002,-0.370103864,-1.7447625569999998,-1.302032363,0.74019438,1.309956944,-11.09138589,-15.11667183,-9.022924629,-10.89742574,-10.26687474,-10.15303251,-6.231782626,-1.63233183,-1431.084926333744 -3946,3946,D231R,-0.029619827,-0.069495134,-0.037858882999999996,-1.593219528,-2.435618255,-0.011435605,-0.024178134,-0.035061519,0.013025219,0.013028031,-0.152018299,-0.002427939,-0.073289827,-1.442011022,-1.7444280330000002,-2.375651778,-2.4955847319999998,0.800768446,0.717246037,-15.3165288,-20.26387109,-11.12590406,-15.06020176,-15.41047896,-14.72218814,-7.937800905,-4.6524426619999995,-1433.619838066399 -3947,3947,D231T,-0.029162023999999998,-0.057831648,-0.025067172999999998,-0.905203042,-1.6948748759999999,-0.10030240800000001,-0.007965576,-0.050358472,-0.017628374,0.016527136,-0.132190432,0.008892259,-0.059026604,-0.691574679,-1.118831404,-1.783003084,-1.6067466680000002,2.058013686,1.5823195209999998,-12.88532298,-17.11983724,-11.07061105,-12.26683265,-12.17877994,-11.79055403,-7.530063402000001,-4.575727903,-1431.677232190501 -3948,3948,D231W,-0.01440188,-0.068342765,-0.079749356,-1.614615125,-2.6888924989999996,-0.012127568,0.003968834,-0.032772594,-0.01696164,-0.027823518999999998,-0.10886201,-0.132876326,-0.026622386,-1.6932786130000002,-1.5359516359999998,-2.7518581060000002,-2.6259268909999998,1.0177030059999999,0.710404665,-17.37247532,-19.63995239,-14.73155366,-16.65793226,-18.80848065,-17.02445762,-9.997386382,-7.224716754,-1439.1865870337933 -3949,3949,D231V,-0.021635991,-0.056438037,-0.029804099,-1.418040477,-2.121734009,-0.130585275,-0.006528023000000001,-0.036743959,-0.027080272000000002,0.03748749,-0.150363564,0.050674658,-0.110282856,-1.2666895809999998,-1.5693913730000002,-2.091185868,-2.15228215,0.504656605,0.708746405,-15.541553400000002,-19.60045148,-12.72671576,-14.39001877,-15.89206888,-15.09851211,-9.388199098,-6.464888676,-1436.1951763750985 -3950,3950,D231Y,-0.035408643999999996,-0.068099344,-0.044574367999999996,-1.340158007,-2.29251386,-0.00430867,-0.026289987,-0.044527301,0.061274864000000005,0.06692145099999999,-0.20312013899999998,0.0009328139999999999,-0.090081549,-1.183881637,-1.496434377,-2.212497907,-2.372529812,0.643764212,0.7244266070000001,-19.444442300000002,-22.94796281,-16.73211481,-18.12389132,-20.66852049,-18.74972209,-10.53155042,-8.194205584,-1426.7352700172924 -3951,3951,K232A,0.073543302,-0.7660081470000001,-1.948488494,-2.0429487219999998,-2.767989534,-0.081793325,0.085738415,0.061348188,0.09191735599999999,-0.847752287,-0.6842640059999999,-2.0728870130000003,-1.824089974,-2.20120549,-1.884691954,-2.607547589,-2.9284314780000003,0.37525609600000004,-0.588503511,-7.690485501,-7.224586563,-8.135931503,-8.40393261,-7.467156043999999,-7.220820786,-6.774196565,-6.631834117,-1443.5754329483025 -3952,3952,K232C,0.061430049,-0.771615624,-1.889817967,-2.322201298,-2.572818371,-0.075518355,0.112126741,0.010733356000000001,0.11668339,-0.8317005479999999,-0.7115307,-1.826168059,-1.953467875,-2.204364009,-2.440038587,-2.7867973669999997,-2.358839375,2.006635364,0.189572367,-10.69976607,-10.35565501,-11.10945867,-11.43157479,-10.78219494,-9.819946938,-8.744974317999999,-11.25201849,-1450.5904058879241 -3953,3953,K232E,0.063966276,-1.3460314290000002,-2.109651813,-2.2181264030000003,-2.3411072230000003,-0.058302935,0.073244112,0.05468844,0.08506805099999999,-1.26314201,-1.4289208480000002,-1.96757491,-2.251728715,-2.220832124,-2.215420682,-2.326144227,-2.3560702190000002,-0.256491539,-0.782703596,-10.28574978,-10.14712431,-10.51823478,-10.96302866,-10.18988445,-9.610476707,-8.744974317999999,-11.25201849,-1442.7195248831995 -3954,3954,K232D,0.064933144,-1.6036537659999999,-1.955319779,-2.563794369,-2.4253358169999997,0.015109717,0.10217797099999999,0.027688317,0.06923477900000001,-1.62089963,-1.5864079009999998,-2.27957504,-1.631064518,-2.356740994,-2.7708477439999997,-2.6381443559999997,-2.212527277,-0.602673123,-1.028445642,-10.73892904,-10.17700193,-11.29808409,-11.66785584,-10.70428182,-9.847421501,-8.744974317999999,-11.25201849,-1443.217218332924 -3955,3955,K232G,0.110905655,-1.235698896,-1.84441732,-2.238105482,-3.141039615,-0.083689184,0.11955945,0.102251859,0.058762953,-1.3311181779999999,-1.140279614,-1.834891627,-1.8539430119999998,-2.046756156,-2.429454808,-3.369552203,-2.9125270260000002,3.212951997,1.01462394,-10.65375057,-10.34063372,-10.9588671,-11.40688422,-10.66332354,-9.899044281,-8.744974317999999,-11.25201849,-1428.748039199505 -3956,3956,K232F,0.090013204,-1.7967385359999999,-2.17398081,-1.867803514,-2.317390591,-0.13214657,0.11831506300000001,0.061711345,-0.12503804400000001,-1.840972122,-1.752504949,-2.198617536,-2.149344084,-1.798662236,-1.9369447919999998,-2.557186852,-2.077594329,-0.343888897,-1.1379357,-11.50452171,-11.24553249,-12.23486275,-12.15371226,-11.74861314,-10.13988791,-8.744974317999999,-11.25201849,-1455.2446747217327 -3957,3957,K232I,0.077505328,-1.37310446,-1.923740477,-2.293654441,-2.305710886,0.000307249,0.11898668,0.036023975,0.142530047,-1.303615553,-1.442593367,-2.184139712,-1.6633412419999998,-1.960275671,-2.62703321,-2.542709029,-2.0687127419999998,-0.12950747599999998,-0.796770082,-9.336810474,-9.552835533,-10.18445738,-9.892172112,-8.917527084,-8.137060257,-7.255308863,-7.194662168,-1448.779499037657 -3958,3958,K232H,0.029465005,-1.608602736,-2.025435634,-2.041564508,-2.819360412,-0.059017493,0.051965912999999996,0.006964097,0.008744913,-2.0025855569999997,-1.214619914,-2.059200976,-1.991670291,-2.13636693,-1.946762086,-3.0198302839999998,-2.61889054,-0.409005344,-1.105501505,-10.00958271,-10.09406387,-10.34819521,-10.47480766,-9.492454239,-9.638392601,-8.744974317999999,-11.25201849,-1450.5169187453575 -3959,3959,K232M,0.08447579599999999,-1.725535054,-2.1652466969999997,-2.597630029,-2.459171476,-0.09996729,0.123313354,0.045638238,0.001279864,-1.844517402,-1.606552706,-2.3271015530000003,-2.003391841,-2.404267508,-2.790992549,-2.68567087,-2.232672081,-0.419713412,-1.091112429,-11.07135051,-10.91415833,-11.80742413,-11.86289611,-10.94793958,-9.824334389,-8.623810746,-10.34132175,-1454.1675276495516 -3960,3960,K232L,0.006560852,-1.766377365,-2.153721333,-2.29908903,-3.171225127,-0.030077978,0.020051739,-0.006930036,-0.026144048,-2.090161363,-1.442593367,-1.8659501719999998,-2.441492493,-2.244146122,-2.354031937,-3.370647524,-2.9718027289999998,-0.543038417,-1.130320421,-9.43603049,-9.353606667000001,-10.31724256,-10.41808569,-9.01531192,-8.075905617,-7.365328747,-7.328917167999999,-1448.395478874445 -3961,3961,K232N,0.103629755,-0.925740171,-1.9306186980000002,-2.300532661,-2.312589106,-0.050263826,0.13543875800000002,0.071820752,0.181573083,-0.9176410770000001,-0.9338392640000001,-2.229529001,-1.6317083940000001,-2.306694955,-2.294370366,-2.588098317,-2.037079894,0.180452946,-0.620471113,-9.993179579,-9.381142319,-10.76366141,-10.76217239,-9.870181351,-9.188740433,-7.8607096510000005,-7.967380962000001,-1444.3100882964209 -3962,3962,K232Q,0.10719943300000001,-1.392054498,-2.051432487,-2.094740194,-2.5839178940000003,-0.021317778,0.135332172,0.079066694,0.076115696,-1.548275708,-1.235833288,-1.993071297,-2.109793677,-2.070237252,-2.119243135,-2.8287618689999996,-2.339073918,-0.539286087,-0.994435159,-8.053912241,-7.838320564,-8.612745177999999,-8.542232491,-7.587720337,-7.688542633,-7.489686091,-7.325799114,-1439.5715080834925 -3963,3963,K232P,0.015493356000000002,-1.7421605059999998,-2.108614335,-2.512195488,-3.126311925,0.031407025,0.048416615,-0.017429904,-0.07685439200000001,-1.989698644,-1.4946223669999998,-2.1935291930000003,-2.023699477,-2.6463587619999998,-2.378032214,-2.8308521110000004,-3.4217717380000003,-0.31520725,-1.135472472,-10.84425167,-10.48879866,-11.26675576,-11.56188834,-10.87240014,-10.03141547,-8.744974317999999,-11.25201849,-1465.6787911509164 -3964,3964,K232S,0.105428878,-0.9898810459999999,-2.085286912,-2.144111735,-3.1104106889999996,-0.042518389000000004,0.137735641,0.073122114,0.068454789,-1.10474279,-0.8750193009999999,-2.378842152,-1.791731671,-2.103825589,-2.18439788,-3.33947146,-2.881349918,0.16681422,-0.69607527,-10.31687665,-9.820918045,-10.54060307,-10.99701662,-10.32670755,-9.899137955,-8.744974317999999,-11.25201849,-1446.6747298734263 -3965,3965,K232R,0.064445581,-0.06086756,0.022663237000000003,-0.028213132000000002,-1.6105096319999999,0.026038111,0.094699232,0.034191928999999996,0.063558453,-0.17713307,0.05539795,-0.057326338,0.102652811,-0.053825149,-0.002601115,-1.880947867,-1.340071396,0.8714608779999999,1.31066779,-3.630975427,-3.535489922,-4.39150013,-3.6950628360000004,-2.80584742,-3.72697683,-3.5143688269999998,-2.9492701660000002,-1442.9772584969178 -3966,3966,K232T,0.083565921,-0.906068049,-2.053486039,-2.134110555,-2.7482269919999998,-0.07974870099999999,0.08704581199999999,0.08008603,0.09292581300000001,-1.039174172,-0.7729619259999999,-2.252136791,-1.8548352869999998,-2.02827275,-2.239948359,-2.735644845,-2.760809138,0.20674585399999998,-0.663600732,-8.359550648999999,-7.844947609,-8.847665572999999,-8.970301376,-8.196747375,-7.938091309,-7.023709431,-7.448672964,-1446.358565974515 -3967,3967,K232W,0.001001222,-1.931671252,-2.3379095000000003,-2.113660606,-2.753353303,-0.01043169,0.02321227,-0.021209827,-0.096601726,-1.9600873280000002,-1.903255176,-1.7736646969999998,-2.902154302,-2.093868701,-2.13345251,-2.9773320539999997,-2.5293745519999997,-0.46540647,-1.132042495,-11.09683582,-10.97409312,-11.65188921,-11.75323758,-11.15150097,-9.953458214,-8.744974317999999,-11.25201849,-1453.8579471129924 -3968,3968,K232V,0.025038074,-0.979286566,-2.206013843,-2.770017892,-2.719604968,-0.106735144,0.054507087999999995,-0.004430941,0.13573722,-1.067712206,-0.8908609259999999,-2.688599055,-1.72342863,-2.288643755,-3.251392028,-2.746138376,-2.69307156,-0.029632412,-0.688625712,-10.67735144,-10.74047121,-11.331510699999999,-11.25839244,-10.41691615,-9.639466721,-8.328212313,-9.200912815,-1445.7088765534572 -3969,3969,K232Y,0.011627972,-1.7383571130000002,-1.87703876,-2.096437725,-2.4095241659999997,-0.039099912,0.017553965,0.005701979,-0.082547673,-2.076831586,-1.399882639,-2.258385741,-1.4956917790000002,-2.335551695,-1.857323755,-2.6169550569999998,-2.202093274,-0.371691475,-1.135335068,-11.20323113,-10.99004288,-12.02360719,-11.6689734,-11.46183777,-9.871694405,-8.744974317999999,-11.25201849,-1452.9992510853335 -3970,3970,S233A,-0.0029132840000000004,-0.008919141,-0.029015492,-0.041034287,-1.023786368,-0.12300067699999999,-0.030137135,0.024310567,0.033343499,-0.016752081999999998,-0.001086199,-0.045282018,-0.012748965,-0.05352988,-0.028538692999999997,-0.870418499,-1.177154236,1.6019143409999999,1.6886808340000001,-4.7778343539999995,-3.966458855,-5.275302666,-4.187797821,-5.126283005,-5.333329422,-5.380325939,-3.2904786319999997,-1457.3983737789094 -3971,3971,S233C,-0.056668422999999996,0.005768198,-0.205672685,-1.798893223,-1.777677999,-0.12082224800000001,-0.067321836,-0.04601501,0.042712274,-0.060262707,0.071799103,-0.082084666,-0.329260703,-1.862126635,-1.73565981,-2.2805929640000002,-1.274763034,0.912067208,0.682757946,-7.697366183,-6.312558243,-8.52914019,-6.966422661,-9.029300621,-7.649409202999999,-5.625619136,-3.1919391939999997,-1464.3978934898041 -3972,3972,S233E,0.041641452999999995,-0.581458427,-1.934678895,-2.5894492909999998,-2.908854686,-0.142116999,0.041089017,0.042193889000000005,0.020777969,-0.662083385,-0.500833469,-1.987569432,-1.881788358,-2.764150868,-2.414747713,-3.085707184,-2.732002187,1.4738798180000001,-0.11873266699999999,-9.259359868999999,-9.211722496,-8.115876289,-9.231649307,-9.159769089,-10.57778217,-6.526460002,-4.020571731,-1472.0144741926342 -3973,3973,S233D,-0.021052591000000002,-1.5742513319999998,-2.224201709,-2.407968079,-2.815419103,-0.173279584,-0.023664668,-0.018440513000000002,-0.07879575,-1.9601689999999998,-1.1883336629999999,-2.088374488,-2.3600289290000003,-2.643107176,-2.172828981,-2.964663491,-2.6661747140000003,-0.25781747899999996,-1.117005097,-11.1971903,-11.19294387,-11.96260175,-10.82149415,-10.03824068,-11.97067107,-7.8202582,-6.630980121,-1470.265125980135 -3974,3974,S233G,0.033394994,0.04291568,0.006717936999999999,0.008200309,-0.302187877,-0.120330205,0.013693091000000001,0.053096896,0.00267282,0.017095324,0.068736036,-0.016792961999999998,0.030228835,-0.011554552,0.027955169,-0.255220885,-0.349154869,1.538484432,2.155613264,-5.956546628,-6.022981917999999,-5.4462358779999995,-5.33016497,-6.3358261570000005,-6.647524216,-4.655795161,-3.163854358,-1458.6288815727457 -3975,3975,S233F,-0.09056416800000001,-0.7025668540000001,-2.0543633999999997,-2.598209422,-2.679054189,-0.048705548,-0.102155796,-0.07897254,0.007204959,-0.637244109,-0.7678895990000001,-2.087668892,-2.021057908,-2.165280325,-3.031138518,-2.7878666360000004,-2.570241742,0.76645888,-0.450964895,-11.27114156,-10.5059341,-12.41811362,-9.126551445,-11.25568946,-13.04941917,-6.76022354,-4.174097506,-1471.7865791120566 -3976,3976,S233I,-0.016276483,-0.9273547940000001,-2.443502052,-2.3262384259999997,-2.5831744519999997,-0.10789686,-0.001957902,-0.030595063999999998,0.074180831,-1.029704337,-0.825005251,-2.464334853,-2.42266925,-2.064825031,-2.58765182,-2.8635026010000004,-2.302846302,0.256310146,-0.6629514320000001,-9.288046442,-8.630319527000001,-9.82844252,-9.341320076,-8.70461039,-9.935539696000001,-5.913011766,-2.449569311,-1459.5791044933721 -3977,3977,S233H,0.021699277000000003,-0.188259168,-1.579530864,-2.022554204,-2.540929603,-0.157985318,0.039852796,0.003545758,-0.018153172,-0.18918477600000003,-0.18733356,-1.9986315019999998,-1.160430226,-1.900151676,-2.144956732,-2.6988292460000003,-2.38302996,0.894721186,-0.112637335,-9.935730826,-9.637008224,-9.996872726,-7.34124543,-9.94106942,-12.76245833,-6.602254827,-4.5167972,-1470.1076380168088 -3978,3978,S233K,-0.094792722,-0.65658223,-2.377518646,-2.076266627,-2.429145416,-0.036082733,-0.073034849,-0.11655059400000001,0.10152942699999999,-0.516037423,-0.797127037,-2.411398778,-2.343638513,-2.011888956,-2.1406442980000002,-2.333445271,-2.524845561,0.282454551,-0.505821621,-11.02515488,-10.53993854,-11.8891048,-9.442303276,-10.47039078,-12.78403699,-8.461979646,-8.36621116,-1464.7824084036984 -3979,3979,S233M,0.06756770599999999,0.056163505999999995,-1.515111712,-2.142525942,-2.495404731,-0.158393998,0.0511371,0.08399831099999999,0.063620542,0.061657562,0.05066945,-1.654819633,-1.3754037909999999,-2.510582316,-1.774469567,-2.531108636,-2.4597008259999997,0.299211971,-0.009781066,-11.17005204,-10.68482142,-11.58850202,-10.8575474,-10.89691033,-11.82247903,-7.521678822999999,-5.925439926,-1469.2347398484126 -3980,3980,S233L,-0.047554248,-0.017874927,-1.527855187,-2.212910268,-2.653834687,-0.07045769,-0.044620847000000005,-0.050487647999999996,-0.009286563000000001,0.013255807,-0.049005661,-1.525889056,-1.529821317,-2.1733757959999997,-2.252444739,-2.561878901,-2.745790472,0.57748207,0.025442364,-11.58674515,-11.10211312,-12.85292254,-11.170969,-11.90112625,-10.90659482,-7.735812159,-5.925439926,-1460.776739724446 -3981,3981,S233N,-0.058782783,-0.167112867,-1.700682974,-2.27947458,-2.837440603,-0.065443339,-0.040372319,-0.077193247,0.01072854,-0.075063585,-0.259162148,-1.971814683,-1.429551265,-2.6514861069999998,-1.907463053,-2.9730424230000003,-2.701838782,0.311639603,-0.152816962,-7.445867848,-8.252419197,-7.84375074,-6.691624702,-5.923015648,-8.518528953999999,-5.627639628,-2.227014411,-1458.3026713468134 -3982,3982,S233Q,0.033588952000000005,-0.023655387000000003,-1.54862578,-2.465455085,-2.395784855,-0.136311246,0.032653695,0.034524208,-0.0462634,-0.04812417,0.000813397,-1.7203977030000002,-1.376853857,-2.27513039,-2.655779779,-2.596686706,-2.194883003,0.513246757,-0.021692057999999997,-9.231069858,-9.089938888999999,-8.897967278,-7.668412712,-9.585470917,-10.91355949,-5.975568381,-2.316464156,-1462.933670594357 -3983,3983,S233P,0.015138462,0.031077404,-0.020468163,-0.5368836339999999,-1.8622693369999999,-0.123847399,-0.031721521,0.061998445,-0.0077061890000000004,-0.02706043,0.08921523699999999,-0.061832350999999994,0.020896026,-0.306131817,-0.767635451,-1.8477962209999998,-1.876742453,1.448092214,1.36903937,-5.499267377000001,-3.6259440460000003,-5.251581093,-3.9961682510000003,-7.095897742999999,-7.52674575,-3.976412237,-1.8061968730000002,-1474.607725283131 -3984,3984,S233R,-0.048622835,-0.357468884,-1.905316494,-2.3901128590000003,-3.0796995989999996,-0.0146084,-0.045116212,-0.052129457000000004,-0.003932202,-0.33301734,-0.381920427,-2.0736755419999997,-1.736957446,-2.276225711,-2.5040000069999997,-3.0749032819999997,-3.0844959160000003,0.9613668059999999,-0.188923128,-8.691011115,-9.177626465,-7.987243546,-6.983063133,-9.194494896,-10.11262753,-6.473013474,-4.504735051,-1455.2755112801678 -3985,3985,S233T,0.041391567000000004,0.05976864900000001,-0.016953331999999998,0.008724631,-0.036772807000000005,0.18464142100000003,0.025467528,0.057315606,0.022945881,0.012518895,0.107018402,-0.049191958,0.015285295,-0.031135995,0.048585257,-0.043851792,-0.029693822,1.253544913,2.438382286,1.552480899,1.357504593,2.273680122,0.5094898379999999,1.5604938130000001,2.06123613,-0.399767727,2.0504422780000002,-1475.8473792169243 -3986,3986,S233W,-0.014515148,-0.024619921,-1.337217823,-2.283506596,-2.514866361,-0.062181935,-0.007492678000000001,-0.021537617000000002,0.025171943,-0.037336158,-0.011903684,-1.475969417,-1.198466228,-2.757700832,-1.809312359,-2.6021358930000003,-2.427596829,0.641043873,0.038702641,-12.46210702,-11.66486829,-13.05842155,-10.87946792,-12.3629908,-14.34478655,-8.461979646,-8.36621116,-1472.0578513867222 -3987,3987,S233V,-0.003185508,-0.028056888,-1.435155577,-2.025274202,-2.8191033360000004,-0.11876076099999999,-0.007836195,0.001465179,0.002142543,-0.018939485,-0.037174291,-1.535043044,-1.335268109,-2.0598125080000003,-1.990735895,-3.381368824,-2.256837847,0.805654504,0.03887636,-8.449287708,-7.507466934,-9.504335724,-8.277966629,-7.610648277,-9.346020973,-5.818733606,-3.2552296239999996,-1461.9389918991365 -3988,3988,S233Y,-0.007312254,-0.051809435,-1.595145808,-2.0962767319999998,-2.7167121219999997,-0.058815155,0.009462031999999999,-0.024086539,-0.074815302,0.021828524,-0.125447394,-1.9942754530000002,-1.196016163,-2.071886885,-2.1206665780000002,-2.8705644560000003,-2.562859788,0.335098279,-0.132583482,-11.76270984,-11.20507112,-13.12136493,-9.102277687,-10.89546326,-14.48937221,-6.593961966,-3.1953178330000003,-1463.9552113320678 -3989,3989,G234A,0.02863772,-0.001013679,-0.014388006000000002,0.010276011,-0.451187719,-0.08219046599999999,-0.009846141999999999,0.067121582,-0.033045633,0.018556872,-0.02058423,0.0025200870000000003,-0.031296098,0.027390464,-0.0068384430000000005,-0.393264644,-0.509110793,1.00888511,1.619179944,-6.306129655,-6.258641097999999,-6.444292647999999,-6.2411720729999995,-6.455270515,-6.131271942000001,-6.729732471,-5.946089075,-1451.8338925004937 -3990,3990,G234C,-0.000311783,-0.012054500000000001,-0.010929521999999999,-0.00472517,-1.561572545,-0.05531149,-0.011105364,0.010481799,-0.017877536,-0.00267501,-0.02143399,-0.009981653,-0.011877391000000001,0.054793874000000006,-0.06424421400000001,-1.703851245,-1.419293844,0.6025916570000001,1.307261529,-10.43842499,-10.6162741,-10.30271465,-10.42190092,-10.52473339,-10.32650192,-9.185551772,-11.79063775,-1460.731076032389 -3991,3991,G234E,-0.045315113,-1.058921167,-1.977628526,-2.138036628,-2.321554784,-0.02033968,-0.028896897,-0.061733328,0.034228411,-0.878398813,-1.2394435209999999,-1.946796501,-2.00846055,-1.748649069,-2.5274241859999997,-2.2051710780000002,-2.437938489,4.138613611,2.153247598,-10.39952753,-10.22866742,-10.42123166,-10.38530894,-10.66152987,-10.30089978,-9.177886845,-11.74813046,-1458.301821119152 -3992,3992,G234D,0.02294372,-1.588138586,-1.957331915,-2.38977404,-2.715611985,-0.081785481,0.017880819,0.028006621000000002,-0.10343415,-1.7036824069999998,-1.4725947640000001,-1.8726243919999999,-2.042039438,-1.866362487,-2.913185593,-2.658676597,-2.772547373,-0.272881496,-1.102085595,-9.770944043,-9.756021835,-9.948399704,-9.66662532,-9.822440353,-9.661233002000001,-8.137221204,-7.910816956000001,-1455.669005685486 -3993,3993,G234F,-0.013340527,-0.34360408299999995,-1.6797953540000001,-2.644369207,-2.606707788,-0.068570357,-0.020224715,-0.006456339,-0.009222664,-0.317924056,-0.36928411,-1.72990409,-1.629686617,-2.036906637,-3.2518317760000004,-3.1022220189999996,-2.111193556,1.409740339,0.071816329,-10.40542533,-10.51056316,-10.38879648,-10.30291407,-10.5271024,-10.29775055,-9.185551772,-11.79063775,-1465.4007606399246 -3994,3994,G234I,0.017278238,-1.4382608369999998,-2.029519955,-2.9869735889999998,-2.648282175,0.017984054,0.049648539000000005,-0.015092063999999999,-0.11545232,-1.730005134,-1.14651654,-2.2211664140000003,-1.837873496,-2.7500177110000004,-3.2239294660000004,-2.514303098,-2.7822612510000004,-0.236967598,-1.1068479690000002,-10.41925751,-10.50464202,-10.47195818,-10.39855775,-10.54267944,-10.17845016,-9.185551772,-11.79063775,-1459.4698194223456 -3995,3995,G234H,-0.071572495,-1.554517198,-1.957400961,-2.747627718,-3.010996295,0.030767332999999997,-0.06511952,-0.07802547,-0.06598407099999999,-1.572287375,-1.53674702,-2.0013007480000002,-1.9135011730000002,-2.7520007939999998,-2.7432546419999997,-3.118346172,-2.903646418,-0.110587603,-1.027089495,-10.41854019,-10.27740331,-10.36786759,-10.49305637,-10.58521826,-10.36915543,-9.185551772,-11.79063775,-1466.288964251522 -3996,3996,G234K,-0.042857617,-1.562354054,-2.6965190839999997,-2.509624587,-3.099599421,-0.031145079,-0.047132499,-0.038582735,-0.20298674,-1.7739610030000001,-1.350747105,-2.130423709,-3.262614459,-2.4040025000000003,-2.615246674,-3.247469133,-2.951729709,-0.11827156300000001,-1.152899961,-10.45424748,-10.51528107,-10.50200573,-10.39123663,-10.57730575,-10.28540823,-9.185551772,-11.79063775,-1467.1342089665122 -3997,3997,G234M,0.024403547,0.06591409299999999,0.032693439,-0.12057512199999999,-2.433627533,-0.090968558,0.022368109,0.026438985,-0.0008810080000000001,0.05171755,0.080110636,0.047564330999999994,0.017822547,-0.073680226,-0.167470017,-2.2612114869999997,-2.606043578,0.793066976,1.27769163,-10.39744546,-10.31026997,-10.25030527,-10.48635746,-10.58432303,-10.35597157,-9.185551772,-11.79063775,-1464.518300278578 -3998,3998,G234L,-0.014686451000000001,-0.809411792,-2.0843616369999998,-2.35050456,-2.699437057,0.01814068,-0.006376118,-0.022996783,-0.040923087000000004,-0.778744711,-0.840078873,-2.325857396,-1.842865877,-2.326434915,-2.374574204,-3.044962812,-2.353911301,0.653942266,-0.542154185,-10.39558183,-10.46600101,-10.29216428,-10.35918356,-10.51693811,-10.34362217,-9.185551772,-11.79063775,-1460.7900241864845 -3999,3999,G234N,-0.024967421,-0.609571955,-1.794934052,-2.569402284,-2.9832858589999995,0.027463486000000002,0.001740515,-0.051675357000000005,-0.04314524,-0.474555127,-0.744588782,-1.935753184,-1.65411492,-1.862544489,-3.2762600789999996,-3.131979854,-2.8345918639999996,1.171064495,-0.19067294,-10.41985786,-10.41463962,-10.36607552,-10.43760779,-10.53366042,-10.34730596,-9.185551772,-11.79063775,-1453.7960796765983 -4000,4000,G234Q,-0.047122135999999995,-0.501619381,-2.015615443,-2.954174796,-2.478982746,0.002518225,-0.06968447700000001,-0.024559794,-0.035789286000000003,-0.412023635,-0.591215126,-2.293334679,-1.737896207,-2.52115598,-3.387193612,-2.489561349,-2.468404142,0.352765693,-0.474355865,-10.45483892,-10.46871574,-10.33889546,-10.56854253,-10.57324558,-10.32479527,-9.185551772,-11.79063775,-1458.5764015149325 -4001,4001,G234P,0.002964446,-1.7622340380000001,-2.241413739,-2.550705022,-3.176723071,0.033272983,-0.045932057000000005,0.051860949,-0.205609947,-1.734257625,-1.79021045,-2.322328918,-2.16049856,-2.578178942,-2.523231102,-3.041434334,-3.3120118080000003,0.150036361,-1.131681049,-10.46165855,-10.47306409,-10.29586998,-10.58253554,-10.58524729,-10.37157586,-9.185551772,-11.79063775,-1466.0313873691484 -4002,4002,G234S,0.018120186,0.028404317000000002,-0.015168879,0.028842321,-1.605763109,-0.077978752,-0.005472224,0.041712596,-0.045727847,0.02044486,0.036363772999999995,-0.02933032,-0.001007438,0.040513183,0.017171458,-1.6183135419999999,-1.593212675,0.748420535,1.318110479,-8.314960323,-8.306355858,-8.430583405,-8.257491631,-8.369066422000001,-8.211304298,-7.873708945,-7.54889086,-1441.0506777241826 -4003,4003,G234R,-0.039126456000000004,-1.7141974569999998,-1.9797661659999999,-2.435319155,-2.901957822,-0.020290877,-0.040068666,-0.038184245,-0.177344135,-1.810133982,-1.6182609319999999,-1.927714599,-2.031817733,-2.440175479,-2.43046283,-3.061793362,-2.7421222810000003,0.065340873,-1.11885147,-10.42583389,-10.46886327,-10.38482246,-10.41553636,-10.6061175,-10.25382987,-9.154490617,-11.37314356,-1459.5564302634448 -4004,4004,G234T,0.031195985,-1.081721343,-2.046177788,-2.333037854,-3.3294693669999997,-0.024475185,-0.017493792,0.079885762,0.0037230690000000003,-1.138875411,-1.024567274,-2.189344702,-1.9030108730000002,-2.0302213780000002,-2.63585433,-3.5105101089999997,-3.1484286239999997,0.40146603799999997,-0.691296483,-10.39642932,-10.40357899,-10.454572099999998,-10.48048015,-10.48601909,-10.15749628,-9.185551772,-11.79063775,-1444.3213664982468 -4005,4005,G234W,0.015597611,-1.58791409,-2.1907881280000003,-2.204593901,-2.90549311,-0.00566266,0.025535132000000002,0.005660089,-0.170899374,-1.50366106,-1.672167119,-2.052814286,-2.328761969,-2.171491118,-2.237696684,-2.8388664919999997,-2.972119728,3.506104314,1.03420937,-10.45593116,-10.38541417,-10.53499925,-10.48162762,-10.54279255,-10.33482218,-9.185551772,-11.79063775,-1463.9656116166152 -4006,4006,G234V,-0.02360701,-1.428594905,-1.9484004990000001,-2.411244085,-2.74767668,-0.014247851,-0.016472026,-0.030741993999999998,-0.07120542,-1.57919129,-1.277998519,-1.879538054,-2.017262943,-2.028178108,-2.7943100610000005,-2.2976134740000003,-3.1977398860000004,-0.642684232,-1.0946746520000001,-10.05566047,-10.12026865,-10.04816708,-10.02479716,-10.147808,-9.937261443999999,-8.867416257999999,-9.658166592,-1453.1392424250953 -4007,4007,G234Y,-0.022137672,-0.15871307099999998,-1.642958163,-2.083699918,-2.784599127,-0.044783243,-0.037154547,-0.0071207959999999995,0.003970054000000001,-0.056540495,-0.260885646,-1.7417533630000002,-1.544162962,-1.839240895,-2.328158941,-2.6827075280000003,-2.886490725,0.6487923520000001,-0.019361066,-10.4410924,-10.46052343,-10.34562449,-10.50005337,-10.5792486,-10.32001213,-9.185551772,-11.79063775,-1464.8855234426446 -4008,4008,A235C,-0.028105971,0.075852876,0.044039947999999995,-1.164923126,-2.08141988,-0.033883588,-0.001411115,-0.054800826,-0.027651207,0.119588018,0.032117732999999996,0.049613015,0.038466881,-0.994322867,-1.335523384,-1.642554446,-2.520285313,2.7317798289999997,2.08239639,-11.51819155,-9.462964745,-10.75461963,-10.25577422,-13.94590936,-13.17168981,-9.31986551,-3.8093664030000003,-1439.9256316344254 -4009,4009,A235E,-0.011691018000000001,0.042006614000000005,-0.210975093,-1.491859997,-2.072320436,-0.115152184,0.065705145,-0.089087181,-0.028445197000000002,0.054009949,0.030003279,-0.130373288,-0.291576897,-1.445636858,-1.538083135,-2.330529066,-1.814111805,1.035496575,0.741344538,-11.6445981,-11.45084269,-9.773081894,-9.266075867,-13.85609575,-13.8768943,-8.520513183,-0.507266673,-1455.7990309153683 -4010,4010,A235D,-0.09194124,0.042963840999999996,-0.98416695,-1.647866272,-2.115127014,-0.09226035099999999,-0.002120893,-0.181761587,-0.070047378,0.081630367,0.004297315,-0.789462329,-1.178871571,-1.7005463930000002,-1.5951861509999998,-2.471495248,-1.75875878,2.42351389,1.231798127,-11.72145004,-9.250252922,-10.55415818,-9.193722244,-16.13366814,-13.47544872,-8.021513392000001,-0.786022617,-1449.6075488873757 -4011,4011,A235G,-0.015009855,0.041144591,-0.013612222,0.012796537,-0.19590627800000002,0.451028253,0.016294393,-0.046314102999999995,-0.07439092,0.059400771,0.02288841,-0.030114374,0.0028899309999999997,-0.029815038,0.055408112,-0.13023378900000002,-0.261578766,1.3465799569999999,2.22810876,-5.690745107000001,-4.832636856000001,-4.658793884,-4.18947393,-8.477126709,-6.2956941529999995,-5.915240371,-0.868158387,-1445.6105648807716 -4012,4012,A235F,-0.015331559,0.03564464,-0.908204115,-1.8197433859999999,-2.7314868010000004,-0.030949492999999998,0.019764146,-0.050427263,-0.055287866,0.047752844,0.023536436,-0.7476329709999999,-1.068775258,-1.586996245,-2.052490527,-2.5620650830000002,-2.900908518,2.284111694,1.167200295,-13.04182528,-11.16146475,-11.78339207,-10.82954465,-17.05699033,-14.37773458,-8.378154133999999,-3.5054297219999997,-1437.407446921803 -4013,4013,A235I,-0.021844542999999998,0.047786775999999996,-0.008456891999999999,-1.101936247,-1.6415324690000002,-0.091961225,0.01584725,-0.059536335,-0.054374899000000004,0.101570387,-0.005996835,-0.012151725,-0.004762058,-0.8227792359999999,-1.3810932569999999,-1.92694277,-1.3561221680000002,1.89680384,1.408201281,-11.36431353,-9.80933593,-10.22682204,-9.209547836,-13.16050863,-14.4153532,-8.853272695,-3.095008238,-1435.8299563731998 -4014,4014,A235H,-0.050384711,0.029431236,-0.7784414479999999,-1.777158094,-2.923896147,-0.055735862000000004,0.021089311,-0.12185873300000001,-0.067214244,0.03487308,0.023989392000000002,-0.609849071,-0.947033825,-1.612279157,-1.942037031,-2.8303860430000003,-3.017406251,1.9520820719999998,0.964241472,-10.55989056,-9.558316498,-9.246012596,-7.980842041,-13.80185712,-12.21242457,-7.797509899,-3.218468263,-1448.9689439940266 -4015,4015,A235K,-0.069329248,0.030898831,-0.772509265,-1.71371466,-2.4592008780000003,-0.12069147300000001,-0.019237598,-0.119420897,-0.07057700900000001,0.011259392,0.050538269000000004,-0.635551415,-0.909467114,-1.6756533830000002,-1.751775936,-2.650722221,-2.267679535,2.096379378,1.0222861909999998,-11.85066568,-11.42397823,-10.84323582,-10.72939079,-13.27336491,-12.98335863,-9.345151199999998,-5.171756881,-1456.0667706443928 -4016,4016,A235M,-0.030704901,0.036352856,-0.016075435,0.008214469,-1.5088820219999999,-0.08181606799999999,0.006175024,-0.067584825,-0.09294853199999999,0.034139164,0.038566547,-0.04925603,0.01710516,-0.009641839000000001,0.026070776,-1.4758600530000001,-1.54190399,0.675564488,1.321332518,-9.151767949,-8.516134201,-9.270973152,-7.8625998610000005,-10.00388454,-10.10524799,-7.448986154,-2.583273555,-1448.9077051207423 -4017,4017,A235L,-0.023488519,0.031821012,-0.019119743999999998,-0.006719813000000001,-1.561597794,-0.068352984,0.012323978000000001,-0.059301015,-0.083658216,0.056100563,0.00754146,-0.042617992,0.004378504,-0.002002899,-0.011436726000000001,-1.48139273,-1.6418028580000001,0.615855202,1.317431963,-10.81891654,-8.122883705,-10.28008495,-8.975374648999999,-12.79539559,-13.92084379,-7.788868083,-2.2944312069999997,-1440.6379387569614 -4018,4018,A235N,-0.071027517,0.055404645999999995,-0.035691518,-0.18641672399999998,-1.827750319,-0.056930851,0.013257623,-0.155312657,-0.057936892000000004,0.051813490999999996,0.05899580000000001,-0.073910402,0.002527366,-0.130714193,-0.242119255,-1.713833386,-1.941667251,1.078612738,1.33740563,-8.918599149,-7.147688484,-8.812515633,-7.648098869,-11.361972999999999,-9.622719757,-6.915562287999999,-1.307764642,-1448.9420657111332 -4019,4019,A235Q,-0.05467455,0.038408686000000004,-0.008853839,-0.650255203,-1.865425273,-0.121890295,0.009034012,-0.118383112,-0.031702992,0.05812324,0.018694131,-0.023035929,0.0053282519999999995,-0.42397479299999996,-0.8765356129999999,-1.6857246,-2.045125945,1.677709855,1.460300213,-9.946223592,-11.52090428,-8.530738273999999,-7.891485741,-11.38268351,-10.40530615,-7.260708673,-2.69286917,-1449.6890784078278 -4020,4020,A235P,-0.019429378,-1.424658577,-1.693481054,-1.8103807719999998,-2.189950193,-0.055055467000000004,-0.002005437,-0.036853317999999996,-0.11274733699999999,-1.329484613,-1.51983254,-1.541576694,-1.845385413,-1.582594574,-2.03816697,-1.6726716469999998,-2.707228738,4.365761308,2.431379288,-12.32889045,-11.62655095,-11.11590831,-11.22559863,-14.50069403,-13.17570032,-11.38411299,-8.108516822,-1461.2618613890372 -4021,4021,A235S,0.010401251,0.038181022,-0.003760595,0.003569439,-0.510609574,0.11061234,0.03386879,-0.013066288999999998,-0.080925361,0.057690879,0.018671164,-0.026744092,0.019222903,-0.051418938,0.058557815,-0.260929322,-0.760289825,1.476019049,2.043273514,-3.9993063980000003,-3.537286377,-3.784333702,-3.0925899119999998,-5.590388886,-3.991933113,-5.205697961,0.494013866,-1458.713947395794 -4022,4022,A235R,-0.0036256390000000004,0.039144301,-0.30902668899999997,-1.5428787830000001,-2.200683192,-0.047224800000000004,0.020704007,-0.027955284,-0.060735356,0.05183901,0.026449591,-0.225317994,-0.39273538399999997,-1.382464269,-1.703293296,-1.900306681,-2.501059703,3.269304576,2.326429437,-10.06662275,-9.126002013999999,-9.874828049,-8.569979431,-10.74576675,-12.0165375,-7.17399448,-2.422895161,-1437.0684984917752 -4023,4023,A235T,0.007971499,0.020406668,-0.022568177999999998,-0.006645009,-1.25967584,0.156841218,-0.0078069640000000004,0.023749961,-0.042745024000000006,0.036592242000000004,0.004221094,-0.065863972,0.020727616,-0.05304959,0.039759572,-0.9831469909999999,-1.536204689,1.792915159,1.7907322469999998,-5.457007298,-5.945702766,-4.986124512,-5.456055022999999,-6.677488976,-4.219665215,-5.641632835,1.1195276840000001,-1449.1741700964049 -4024,4024,A235W,0.026176647,-0.209996459,-1.5504065930000002,-2.022610254,-2.532248478,-0.082580418,0.072118029,-0.019764736,-0.046250848,-0.0207075,-0.39928541799999995,-1.3986321119999998,-1.7021810730000002,-1.8446639630000001,-2.200556545,-2.428526174,-2.635970781,3.0806294189999996,1.554311802,-13.40710953,-9.876178841,-11.49637869,-11.84885735,-16.72697373,-17.08715905,-8.057920532999999,-1.371595226,-1440.4468614375219 -4025,4025,A235V,-0.014581354,0.040542159,-0.011102751000000001,-0.179605979,-1.726128457,-0.089288014,0.036944443,-0.066107151,-0.07172793599999999,0.037455748999999997,0.043628568,-0.030854651,0.00864915,-0.101908174,-0.257303783,-1.432731318,-2.019525596,0.6723808609999999,1.3210154570000001,-10.10180878,-9.59604171,-9.467636208,-9.095258812,-11.76497532,-10.58513186,-9.201091555,-4.421113662,-1436.7782786847092 -4026,4026,A235Y,-0.06511365599999999,0.008960559,-0.400849082,-1.6276882719999999,-2.9049267619999997,-0.072336026,0.010123797,-0.140351108,-0.043185095,0.01131384,0.006607278,-0.313201916,-0.48849624799999997,-1.572147124,-1.6832294190000001,-3.0912840060000004,-2.7185695169999997,1.4172534469999998,0.7893134079999999,-13.31970662,-11.3285424,-11.78512462,-10.7929362,-16.3608126,-16.33111727,-8.042284817999999,-3.293510926,-1439.7633111402392 -4027,4027,G236A,0.054920385,-0.00786816,0.0041942970000000005,0.042776524,-0.236250409,1.4045676809999998,0.04638718,0.063453589,-0.045242464,-0.009638205,-0.006098115,0.004062463,0.00432613,0.040932679,0.04462036900000001,-0.130637802,-0.341863016,1.141619583,2.234523073,-5.9904846570000005,-6.740699188,-6.198597778,-5.525183105,-6.328148323,-5.159794891000001,-5.378278074,-2.351335558,-1440.8820390836336 -4028,4028,G236C,0.016168896000000002,-0.035612002999999996,-0.000123516,-1.557431733,-2.686057566,0.781797972,0.018799879,0.013537913,-0.085019102,-0.084841007,0.013617001,0.002486103,-0.002733135,-1.286967162,-1.8278963030000002,-2.519368437,-2.852746694,0.75016782,0.725861924,-8.433650706,-9.119224792,-7.165339417,-8.499766029,-6.513357468,-10.87056583,-6.06093129,-3.699459731,-1451.5820154407993 -4029,4029,G236E,-0.025605592000000003,0.053935217,-0.342622748,-1.761089106,-2.712110453,0.9481715940000001,-0.014127708999999999,-0.037083474,0.001462491,0.072443761,0.035426672,-0.089704946,-0.59554055,-1.42759753,-2.0945806819999997,-2.643608389,-2.780612516,0.883967682,0.726753262,-11.07687134,-12.66613824,-9.15596666,-9.795286308,-14.64418588,-9.122779593999999,-8.251645,-3.427835284,-1438.5181464059278 -4030,4030,G236D,0.052633837,-0.00289657,-0.010938381,-0.728995961,-2.1808833,0.660405004,0.033892086,0.071375587,-0.027654295,-0.02923162,0.02343848,-0.055345889,0.033469128,-0.528218019,-0.929773902,-2.05842032,-2.303346279,1.596939691,1.340400937,-10.40868176,-13.51851229,-9.3929832,-7.689338188,-12.96562212,-8.476953011,-5.888396052,-3.2705552239999998,-1437.9414270934649 -4031,4031,G236F,0.023655225,-0.17676446899999998,-1.514488812,-2.033961992,-2.9557703269999998,-0.12059494300000001,0.038494357,0.008816092,-0.052371447,-0.053879175999999994,-0.299649762,-1.5772502430000002,-1.451727381,-1.7842791080000002,-2.283644876,-2.585316619,-3.3262240339999996,4.1752142999999995,2.531264474,-13.76695112,-15.03014908,-11.82020096,-11.61685472,-15.12153581,-15.24601501,-6.885241271,-3.1562422189999997,-1424.9697471028194 -4032,4032,G236I,0.05669484,0.013980635,-1.274034575,-1.817826323,-2.9569191089999998,-0.043943384,0.06823079,0.045158889,-0.032207638,-0.020694114,0.048655382999999996,-1.067759695,-1.4803094540000001,-1.8883283690000001,-1.7473242759999998,-2.592455867,-3.3213823510000005,2.503887582,1.134896822,-12.08687547,-14.26152103,-9.609776604,-11.97545664,-13.4790716,-11.10855147,-5.750241114,-1.5413350719999999,-1431.8021313473582 -4033,4033,G236H,0.04394105,-0.007799824,-0.560650643,-1.969638716,-1.9887343830000002,-0.02552734,0.010353933000000001,0.077528167,-0.112005342,-0.054633715,0.039034067,-0.23754148,-0.883759805,-1.838354394,-2.100923038,-2.241451896,-1.73601687,1.300201944,0.72294033,-14.04521766,-16.20570544,-13.49273473,-10.88203595,-15.84487952,-13.80073266,-9.574363502,-7.314840247999999,-1445.4097479190677 -4034,4034,G236K,-0.0503228,-0.5170904470000001,-1.928514672,-2.5483175769999997,-2.771155907,-0.10223396300000001,-0.116282401,0.015636801000000002,-0.021413802000000003,-0.227564365,-0.806616529,-2.198093463,-1.65893588,-2.2589942919999997,-2.837640861,-2.3610617990000002,-3.181250015,0.623919979,-0.30173249399999996,-11.05469652,-13.38614217,-9.933208183,-8.818348557,-15.03904633,-8.09673735,-7.656752772999999,-4.512334836,-1446.4115551472642 -4035,4035,G236M,0.076077303,0.02587162,-1.192713259,-2.152759463,-2.7646734189999997,0.036579289,0.06992599299999999,0.082228612,-0.057617519000000006,0.038085311000000004,0.013657928,-1.0454833000000001,-1.339943217,-1.805354134,-2.500164792,-2.384542895,-3.144803942,2.863739462,1.49016366,-14.21205618,-16.05875796,-10.47703264,-13.76903478,-16.13063683,-14.6248187,-7.122014412,-3.8688708789999997,-1434.5243811826222 -4036,4036,G236L,0.0035140040000000003,-0.31614280899999997,-1.651235634,-2.096764423,-2.99387687,-0.095184697,0.003738939,0.0032890690000000004,-0.045340653,-0.058677208,-0.57360841,-1.554426267,-1.748045001,-1.86199943,-2.331529416,-2.291425871,-3.6963278689999997,3.79842667,2.192439685,-13.13020982,-13.29615464,-9.166885292,-12.9829286,-15.89587486,-14.30920568,-6.114824407,-0.74215118,-1440.4885110971518 -4037,4037,G236N,0.084387894,0.028674557000000003,0.002736551,0.03683882,-1.2087691790000001,1.4338252059999999,0.090863136,0.077912651,-0.0013889629999999998,-0.063372329,0.120721442,-0.008056802,0.013529903000000001,-0.0025804079999999997,0.076258047,-1.154093974,-1.263444383,0.969611214,1.369024506,-8.81307034,-11.81098616,-9.346120369,-4.454513618,-11.99545193,-6.458279625,-5.109286281,-2.968751407,-1442.6766806929372 -4038,4038,G236Q,0.038087266,-0.027078625,-0.807437958,-1.76236379,-3.07324775,0.415829072,0.069515338,0.006659194,-0.061340516,-0.01647346,-0.037683789,-0.489180799,-1.125695117,-1.583505384,-1.941222195,-2.685572891,-3.460922608,1.831040459,0.9301763279999999,-11.01859875,-11.81768144,-9.766072563,-9.569935776,-14.43538501,-9.503918945,-6.895352105,-2.8266956110000003,-1442.9452737905085 -4039,4039,G236P,0.040972019,-1.76898324,-2.151777122,-2.287503711,-3.063569707,-0.122100721,0.028043194,0.053900843,-0.129893171,-1.9019066000000002,-1.636059879,-2.2628412890000003,-2.040712955,-2.365134803,-2.209872618,-2.512959801,-3.614179612,-0.303889358,-1.158243746,-9.695256825,-7.400000641,-8.576845589,-9.982379929,-11.06167657,-11.45538139,-6.376942011000001,-4.3021708080000005,-1448.8614169834182 -4040,4040,G236S,0.050618200999999995,0.010690989,-0.01785845,0.003626732,-1.467128934,1.4272528919999998,0.040005473,0.061230928,-0.029272727999999998,-0.0017380770000000002,0.023120055,-0.016493109,-0.01922379,-0.012432857,0.019686321,-1.246408235,-1.6878496330000001,1.299185752,1.4449782430000002,-5.44332608,-6.441233025,-6.566121033,-3.66125499,-5.999168312,-4.548853043,-4.005352312,-3.120877891,-1436.6993112168275 -4041,4041,G236R,-0.014763252,-0.622823398,-1.836555433,-2.0496448330000003,-2.615893721,-0.056197104000000005,-0.023457015,-0.006069489,-0.060476969000000005,-0.33312123,-0.912525565,-1.797717131,-1.875393735,-1.9835566969999998,-2.115732969,-2.5627454590000003,-2.669041982,1.5362142,0.014015193,-11.92877893,-14.04647554,-10.93394056,-10.48732816,-13.38381291,-10.79233746,-7.9088425760000005,-6.052350264,-1441.4848952842876 -4042,4042,G236T,-0.001385194,-0.006117900999999999,0.001107483,-0.03642424,-1.740199749,1.23885317,-0.010713826999999999,0.007943439,-0.021668358,-0.02697369,0.014737888000000001,-0.011837569,0.014052533999999998,0.006286655,-0.07913513400000001,-1.5291017830000002,-1.951297714,1.052727119,1.330378607,-8.989255266,-9.760221771,-8.335565483,-7.561612602,-10.44659397,-8.842282501,-6.672785381000001,-4.5949103330000005,-1434.8682326669805 -4043,4043,G236W,-0.00414746,-0.36047249600000003,-1.5883721919999998,-2.078936274,-2.740907806,-0.083322945,0.0008197580000000001,-0.009114677,-0.025167382999999998,-0.13143757,-0.589507421,-1.499123459,-1.677620924,-2.134055556,-2.023816992,-2.838183054,-2.643632558,0.964214948,0.061939857,-13.52776256,-13.89034081,-13.049819900000001,-12.00755156,-15.06000651,-13.63109402,-6.695678947999999,-4.416799003,-1442.0075908224098 -4044,4044,G236V,-0.006881796999999999,-0.037952103,-1.285161504,-2.2914729769999997,-3.008813615,0.004531591,-0.004125752,-0.009637841,-0.046413915,0.03258214,-0.108486346,-1.2028923459999998,-1.3674306619999999,-2.485641925,-2.097304028,-3.0648306869999997,-2.9527965430000003,1.826665002,0.476396305,-11.52327332,-14.02641759,-10.52207693,-11.19530595,-11.29552094,-10.577045199999999,-6.462964239,-1.995438169,-1429.7735888990574 -4045,4045,G236Y,0.004943683,-0.231872153,-1.774563795,-2.126810099,-2.977284682,-0.048244934,0.033344442,-0.023457076,-0.002219374,-0.029576826,-0.43416747899999997,-1.5576177709999999,-1.9915098180000002,-1.986495385,-2.267124812,-2.565684147,-3.3888852160000003,2.812348987,1.212091853,-14.01606773,-15.86405241,-13.79184651,-10.75937568,-14.81475333,-14.85031072,-6.704260027999999,-4.977186618,-1431.0993220857345 -4046,4046,E237A,0.021780287000000002,0.013122682,0.002696695,0.010723965,0.004358278,0.329409481,0.012706366,0.030854207999999998,0.037742492,-0.004461775,0.030707138999999998,0.026978215,-0.021584826,0.011727353000000001,0.009720577,-0.0007759160000000001,0.009492471,1.190274632,2.681530754,-1.7230000490000001,-1.042876999,-2.188456757,-2.101392014,-1.735931923,-1.5463425519999998,-2.036443416,0.387706604,-1454.272831866052 -4047,4047,E237C,0.051736014000000004,0.04806995,0.051035383,0.052475840999999995,0.011073096000000001,-0.01764537,0.058828335,0.044643693,0.015383121000000001,0.060040357999999995,0.036099542000000005,0.095683344,0.006387421999999999,0.046285667999999995,0.058666012999999996,0.003102715,0.019043477,1.265153065,2.758888417,-7.751953905,-7.498514572,-8.854867561,-8.580556892,-8.264492996,-5.561337502000001,-6.385090407000001,-3.7830394060000003,-1449.5918375710025 -4048,4048,E237D,0.129920762,0.047613035,0.034996803,0.030155652999999998,0.066875465,0.04395571,0.135514281,0.124327243,0.00324197,-0.000536259,0.09576232800000001,-0.013446969,0.083440574,-0.014215956,0.074527261,-0.017419855,0.151170784,1.189624685,2.483117129,-1.008859439,-0.504138275,-0.9269142229999999,-1.0166974640000002,-1.816116844,-0.7804303890000001,-1.644379766,1.175356731,-1460.9157819133252 -4049,4049,E237G,0.037270041000000004,0.020322382,0.005767481999999999,0.02180569,0.008001971,0.7673142820000001,0.03854652,0.035993561,0.005855366,0.018844458999999997,0.021800305,0.024400152999999997,-0.01286519,0.011386368999999999,0.03222501,0.007929292,0.00807465,1.0872725429999999,2.8251325210000005,-0.63343844,-0.685592117,-1.5292422490000002,-0.112332275,-1.308316971,0.468291412,-0.889596079,1.252001601,-1453.251974129118 -4050,4050,E237F,0.153724933,0.049986438,-0.02540932,0.055841655999999996,0.022973874,-0.066171618,0.179112722,0.12833714300000001,0.047476287,0.004503379,0.09546949699999999,-0.004950031,-0.045868609000000005,-0.0021271999999999997,0.113810511,-0.035525883,0.08147363099999999,1.304347324,2.554738565,-7.826209392999999,-7.786741248999999,-9.531871574,-7.634156699999999,-7.511129974,-6.667147469,-3.923115408,-1.488799733,-1445.0765989017673 -4051,4051,E237I,0.039466995,0.000513951,-0.022627027,0.00763736,-0.278604064,0.213064549,0.041194267,0.037739722999999996,0.028992881,-0.027712941,0.028740842000000003,-0.02247539,-0.022778662999999998,-0.047730055,0.063004775,-0.247763756,-0.30944437199999997,1.085590718,1.7841169559999999,-8.474566351,-6.287865906,-10.72831259,-9.400867172,-8.503458237,-7.45232785,-4.555756074,-0.245710896,-1442.0722899721004 -4052,4052,E237H,0.011325577,0.055101765999999996,0.007777483000000001,0.033230232,0.017693319,0.079610919,0.0014414929999999999,0.02120966,0.006749528,0.066766089,0.043437442,0.050909533,-0.035354567999999996,0.060711483,0.00574898,0.040326054,-0.004939415999999999,1.1133497190000001,2.638047589,-4.984220873,-4.724647827,-5.518680847000001,-4.722360977,-5.429035751,-4.52637896,-4.106831979,-1.6177099869999998,-1449.4677110970952 -4053,4053,E237K,-0.008818906,0.020584535,0.008749543,0.00207233,0.020351337,0.024162714,-0.015203081,-0.00243473,0.014449873,0.019235198999999998,0.02193387,0.052596433,-0.035097348,0.01643458,-0.01228992,0.027386275,0.013316399,1.192568025,2.796023765,-1.8804953919999998,-1.283476852,-1.420520531,-2.385920547,-2.256177727,-2.0563813019999997,-1.708415899,-1.12334336,-1451.1062602102757 -4054,4054,E237M,-0.024339267,-0.001607612,-0.027492539,-0.005991746,-0.01660617,0.044449022000000005,-0.012518659,-0.036159875,0.035613181,-0.04898579,0.045770566,0.028665851000000003,-0.083650928,-0.029932472999999998,0.017948981,0.002606818,-0.035819158,1.267990563,2.835683017,-7.3392546329999995,-6.645161407000001,-7.990439049,-8.980987472999999,-6.923070572,-6.156614662000001,-4.405676593,-1.120437912,-1450.672663755715 -4055,4055,E237L,0.022531059,-0.003476843,-0.010275342,0.025241642,0.02178387,-0.016616726999999998,0.041051223,0.004010894,0.015236013999999999,-0.0038180709999999997,-0.003135615,0.037017276,-0.05756796,0.023981534,0.02650175,0.024727497,0.018840242,1.195692299,2.706288723,-7.630595923,-6.348345527999999,-8.29258593,-9.646323921,-8.501368141,-5.364356094,-4.219657555,0.291238382,-1450.7550346557982 -4056,4056,E237N,0.062287568,0.027558955,0.01971382,0.026362486,0.028963159,0.213054033,0.08783974,0.036735396000000003,0.021612082999999997,0.041625729,0.01349218,0.034456916000000004,0.004970723,0.002279997,0.050444974000000004,0.0013333370000000002,0.05659298,1.13577818,2.5461157880000003,-1.539078392,-0.962950317,-1.5710060730000002,-1.57174353,-1.974481613,-1.615210426,-2.5268971330000003,0.044551579,-1460.879794542212 -4057,4057,E237Q,0.055866474000000006,0.013583835,0.027046884,0.049372207,0.031464553,-0.098277772,0.073977456,0.037755491,-0.031869808,0.026299358,0.0008683110000000001,0.06533710599999999,-0.011243339,0.053420194000000004,0.04532422,0.052932038,0.009997068000000001,1.15149873,2.8459302589999997,-2.9143511369999997,-2.552410797,-3.0521844789999997,-2.707819725,-2.8996105119999998,-3.3597301710000003,-4.331324636000001,-0.91444466,-1453.830291038379 -4058,4058,E237P,0.064673047,0.016898097,0.01298529,0.045290303,0.01334188,0.879597561,0.06112211099999999,0.068223983,0.002832723,-0.014535569,0.048331762,0.014018847,0.011951733,-0.008556985999999999,0.099137592,-0.007948202,0.034631962,1.190206942,2.541524194,-5.711589749,-3.336375763,-7.32109021,-6.720326889,-5.469748267999999,-5.710407616,-3.498589167,0.449849744,-1455.3519629491493 -4059,4059,E237S,0.044308005,0.012462466,-0.024124835,-0.005290478,-0.047764577999999995,0.325162794,0.033265859,0.05535015,0.001883178,0.024343557000000002,0.0005813740000000001,-0.008667625,-0.039582044,-0.019850134,0.009269179,-0.012465406000000002,-0.083063749,1.191086666,2.517326855,-2.1073248280000003,-1.815759651,-2.125610115,-2.863621536,-3.10025209,-0.631380745,-2.502537181,0.606592479,-1454.7363541536033 -4060,4060,E237R,0.045530611,0.040534671,0.03014494,0.030740913999999998,0.028908156,0.106256456,0.05354264,0.037518581,-0.009808532,0.023388678,0.057680663,0.043868082,0.016421797,0.014723341000000001,0.046758487,0.005038931,0.05277738,1.235410105,2.707092308,-3.3653319760000002,-2.4669711690000002,-4.167800461000001,-3.3526413880000003,-3.713146545,-3.126100319,-2.301821628,0.063660658,-1442.7452366137877 -4061,4061,E237T,0.022768817,0.033842372,-0.007626198000000001,0.019304303999999998,-0.086835761,0.42438368200000004,0.023216422999999996,0.02232121,0.002117415,0.040711317999999996,0.026973425,0.03670994,-0.051962335,0.011794448,0.026814159,-0.043992692,-0.12967883,1.35872297,2.542566953,-4.79134041,-3.460786819,-5.216501785,-6.679636238,-5.567997635,-3.031779572,-3.03943117,0.23675860199999998,-1450.2039643567987 -4062,4062,E237W,0.000430592,0.007982886,0.00551169,0.040974098,-0.023706336,0.036092106,-0.0026470929999999997,0.003508277,0.028590942999999997,0.041132231,-0.025166459,0.037607092,-0.026583713,0.060072903,0.021875292,-0.023614722999999997,-0.023797948,1.148176074,2.62011901,-8.419979745,-7.794738799999999,-10.06187313,-8.679413231,-8.243644295,-7.3202292710000005,-4.769548245,-2.2497890369999998,-1443.5548965674825 -4063,4063,E237V,0.016657895,0.016246553,-0.003499815,0.005257035,-0.232596251,0.150908039,0.023062700000000002,0.010253089,0.031151223999999998,0.01142821,0.021064895,-0.014502397,0.007502767,0.010829596,-0.000315526,-0.16783272300000002,-0.297359778,1.286751929,2.152541439,-6.363935059,-4.646724037,-8.195306038,-6.95441021,-5.924248207000001,-6.098986801000001,-3.4433719039999997,-0.23112915399999998,-1444.8972369888797 -4064,4064,E237Y,0.03468529,0.03167615,-0.022749236000000003,-0.002681862,0.005440546,-0.018638248,0.027268042000000003,0.042102537,-0.033591441,0.039892097,0.023460202000000003,0.027770463,-0.073268935,-0.019408778,0.014045055,0.022172346000000002,-0.011291253999999999,1.269385316,2.7386993360000003,-7.294705696,-7.1429911420000005,-8.348777092,-7.013015952999999,-7.0739732360000005,-6.894771057000001,-4.59982177,-1.7497110930000002,-1449.4915894730948 -4065,4065,R238A,0.013523674,-0.006739704,0.005233807,0.001631919,-0.19138277399999998,0.103106836,0.002081165,0.024966183,-0.044662852,-0.00037826,-0.013101148,0.019600328,-0.009132715,0.010257354,-0.006993516,-0.11972578800000001,-0.263039759,1.3547178530000001,2.295813115,,,,,,,,,-1455.3652526936494 -4066,4066,R238C,0.006360838000000001,-0.033718128,0.0067700519999999995,0.013370802,-0.055273876,0.107010355,-0.018394177,0.031115853,-0.023119319,-0.070497449,0.003061194,-0.004808982,0.018349086,0.000221862,0.026519741,-0.062240653,-0.048307099000000006,1.4413432019999999,2.542119829,,,,,,,,,-1460.246258485131 -4067,4067,R238E,-0.022968665,0.029692102,-0.023085342999999998,-0.059469499,-0.540561517,0.045035146,-0.011106481000000001,-0.034830848,-0.060319005999999994,0.082152486,-0.022768282999999997,-0.05078478,0.004614095,0.00618871,-0.125127707,-0.311253214,-0.76986982,1.3633449880000001,1.921643466,,,,,,,,,-1447.4532347084023 -4068,4068,R238D,0.044063275,-0.041944485,0.033812808,0.025038282000000002,-1.57260576,0.185830713,-0.0367761,0.12490265,-0.054581578,-0.098767298,0.014878328,0.013282005,0.05434361099999999,0.037357839,0.012718723999999999,-1.253680672,-1.8915308469999998,0.696717712,1.3362879429999999,,,,,,,,,-1453.1105334931053 -4069,4069,R238G,0.061826717,-0.012828113,0.006560023000000001,-0.014056144,-0.10030088599999999,0.11551189099999999,0.039793422,0.083860012,-0.032907646,-0.030005061,0.004348835,-0.019326799,0.032446844,-0.030106625,0.001994337,-0.082427658,-0.11817411300000001,1.31083945,2.315669824,,,,,,,,,-1453.9712693509646 -4070,4070,R238F,0.029527999,-0.014591693000000001,0.059428278,0.020046416,-0.10410208900000001,-0.00254995,-0.024329616000000002,0.083385613,-0.11114960800000001,0.041871951,-0.071055336,0.085747004,0.033109551,0.023702958,0.016389874,0.070243931,-0.278448109,1.118628365,2.914811813,,,,,,,,,-1467.6406170437112 -4071,4071,R238I,-0.009540119,0.079585897,-0.014749941,0.041987145,-0.6996986820000001,0.145213541,-0.089008089,0.069927852,-0.005096215,0.069858655,0.089313139,0.060677993,-0.090177874,0.089162945,-0.005188655,-0.503501711,-0.895895652,0.682807408,1.4356243819999999,,,,,,,,,-1447.333926717285 -4072,4072,R238H,0.055715427000000005,0.050251504,0.02029348,0.036135912,0.0399595,0.087740469,0.059939837999999995,0.051491015,-0.02407681,0.029860569,0.070642438,0.049718325,-0.009131366,0.046613046,0.025658777,0.062834074,0.017084925,1.137440462,2.850695777,,,,,,,,,-1469.764047367964 -4073,4073,R238K,0.086896117,-0.114179264,-0.058299687,-0.024551467999999996,-0.166125883,-0.137545159,-0.016167021,0.189959254,0.038369479,-0.164810249,-0.063548279,-0.10772643800000001,-0.008872935,-0.16490485900000001,0.115801923,-0.144871436,-0.18738033,1.530227579,2.223333959,,,,,,,,,-1452.183627196122 -4074,4074,R238M,0.07450715200000001,-0.154587341,-0.077156442,-0.041714798,-0.112249205,0.011998868999999999,0.03281944,0.11619486400000001,-0.02737261,-0.231419722,-0.077754959,-0.145913983,-0.008398899999999999,-0.095294585,0.01186499,-0.14120205800000002,-0.083296352,1.433930912,2.17447863,,,,,,,,,-1459.627939987462 -4075,4075,R238L,0.040988432000000005,0.014057097,0.035478592999999996,0.010212888,-0.16812058600000002,0.033932266,0.04165778,0.040319083,-0.008836126,0.018096191,0.010018002,0.042315937000000005,0.028641247999999998,0.023301656,-0.002875881,-0.090550853,-0.24569031800000002,1.383177731,2.37551118,,,,,,,,,-1450.1399128115736 -4076,4076,R238N,-0.034636479,-0.095317611,-0.04953162,-0.095589699,0.034922647,-0.08682265,-0.063993816,-0.005279142,-0.285922825,-0.061269657000000005,-0.12936556400000002,0.026167142,-0.125230381,-0.04571845099999999,-0.145460946,0.053785651,0.016059642,1.192579612,2.685602053,,,,,,,,,-1466.6838722862303 -4077,4077,R238Q,0.10358189599999999,0.025034679,0.050150415999999996,-0.021896667,0.025892083,0.026169811,0.093168389,0.11399540300000001,-0.089917729,-0.010092898000000001,0.060162256,0.001743756,0.098557075,-0.039335155,-0.004458178,-0.021182192000000002,0.072966358,1.228637379,2.520725081,,,,,,,,,-1456.5830644932576 -4078,4078,R238P,0.024899538,-0.007326929,0.00035961099999999997,-0.008658734,-0.41609155700000006,1.085101182,-0.0038290090000000004,0.053628085,-0.042972249000000004,-0.016926088,0.002272231,-0.020907237,0.021626457999999998,-0.030461752,0.013144285,-0.246293323,-0.585889791,1.376820247,2.0210286859999997,,,,,,,,,-1451.9080887064338 -4079,4079,R238S,-0.0027567990000000003,-0.01001807,-0.009010505,-0.008344180999999999,-0.155113138,0.078984082,-0.030310273999999998,0.024796677000000003,-0.001410526,-0.0040145829999999995,-0.016021556,-0.009939947,-0.008081063000000001,-0.004823018,-0.011865343,-0.075726208,-0.23450006699999998,1.308196117,2.3759461859999997,,,,,,,,,-1457.2035061544739 -4080,4080,R238T,0.007056598000000001,-0.045825303,-0.058790893,-0.0013215170000000001,-0.338669016,0.165629506,-0.019518857,0.033632052999999995,-0.012274799999999999,-0.053517922,-0.038132683,-0.07866858,-0.038913206,-0.010637843999999999,0.007994811,-0.205334419,-0.472003613,1.3936531330000002,2.178452388,,,,,,,,,-1457.7783208452165 -4081,4081,R238W,0.007660385,-0.034941222,-0.037390028,-0.021497792999999998,-0.043960948,0.035100761,-0.016887244,0.032208014,0.043752352,-0.047431335,-0.022451109,-0.04863501,-0.026145045,-0.0053176840000000005,-0.037677902,-0.05022631,-0.037695585,1.283728439,2.377140616,,,,,,,,,-1469.6817060648464 -4082,4082,R238V,-0.00942627,-0.021076475,-0.053167945,-0.049975949000000006,-0.238486991,0.14741346800000002,-0.016366651,-0.002485889,-0.0073464509999999995,0.000286821,-0.042439770999999994,-0.010937583999999998,-0.095398305,-0.034737604,-0.06521429299999999,-0.169314658,-0.307659324,1.231832495,2.019396992,,,,,,,,,-1448.176227201242 -4083,4083,R238Y,0.020920823999999998,-0.014267013,0.097452303,0.095098628,-0.015876186,-0.013467264,0.00688754,0.034954107000000005,0.044591569000000005,0.127642224,-0.15617624900000002,0.149450274,0.045454332,0.207093455,-0.0168962,0.060718242,-0.092470614,1.0580714359999999,2.8467654380000003,,,,,,,,,-1477.5452368380502 -4084,4084,G239A,0.001909976,0.0046661229999999995,-0.007806648,-1.047147798,-1.979592571,0.023000187000000002,0.000558151,0.0032618,0.051486983,0.008320056999999999,0.001012189,-0.014491598999999999,-0.001121697,-0.5080322310000001,-1.586263365,-1.9300941930000002,-2.0290909480000003,1.7030476890000001,1.40304414,-6.350715509,-5.377266525,-11.35179063,-6.200394478,-4.76135936,-4.062766548,-4.913885982,-1.533644847,-1441.4390645823441 -4085,4085,G239C,-0.021357437000000003,-0.004849238,-0.056632231,-1.474953956,-2.4281445809999997,-0.071174405,-0.055634137,0.012919264,0.039722138,-0.018669349,0.008970874,-0.02462764,-0.08863682199999999,-1.197072243,-1.752835669,-2.303303751,-2.55298541,0.635493639,0.722194184,-11.58346454,-11.09735013,-15.85688959,-10.6822898,-10.99899721,-9.281795952000001,-8.897488482,-5.3558946380000005,-1445.6806586841121 -4086,4086,G239E,-0.046728088,-0.183592544,-1.389513556,-1.875562709,-2.076001008,0.078745305,-0.01528748,-0.078168695,0.0018879839999999999,0.0016967929999999998,-0.36888188,-1.30268419,-1.476342922,-1.771611161,-1.9795142559999999,-2.2088358880000003,-1.943166128,3.627298362,2.176036025,-9.484589391,-8.966725922,-14.24223277,-8.394125602999999,-9.710336716,-6.10952594,-7.027869214,-3.7383546930000002,-1433.0963854016736 -4087,4087,G239D,0.008714311,0.019566746,-1.106492416,-1.9893299819999999,-2.9632169489999995,0.00341126,-0.0026402609999999996,0.020068882,0.01605822,0.024738057,0.014395435,-0.897809746,-1.315175086,-1.733896391,-2.244763572,-2.8401278989999996,-3.0863059980000003,2.2441887730000003,1.03832865,-8.413449467000001,-8.218256493,-11.30835925,-8.265688042,-8.939020889,-5.335922668,-6.532757759,-2.7615929319999997,-1433.911224595271 -4088,4088,G239F,0.03096675,0.035093196,-1.186166216,-1.946611315,-2.2158135469999998,0.037685815,0.026160932,0.035772567000000005,-0.036707497,0.092619223,-0.022432831,-1.188040125,-1.184292307,-1.85533475,-2.03788788,-1.9615662580000002,-2.470060835,3.458641408,2.097905365,-11.25213823,-13.44058752,-15.04146086,-9.710364608999999,-11.55474697,-6.513531181,-7.41124219,-4.01969675,-1430.6569277513772 -4089,4089,G239I,-0.015741086,-1.179491697,-2.043695784,-2.249033143,-2.367720376,-0.078508564,-0.051316416,0.019834245,-0.087311424,-0.852056512,-1.506926882,-2.0705679530000003,-2.016823614,-2.436832582,-2.061233703,-2.54306409,-2.192376662,1.302751413,-0.360332075,-11.00331891,-11.82043075,-14.49402286,-9.362343376,-10.31694462,-9.022852927999999,-7.269116039,-2.9294414410000003,-1421.6265747067519 -4090,4090,G239H,0.016120136,0.059149050999999994,0.030095353,-1.4965751980000002,-2.5834250340000002,0.24699043399999998,0.004310963,0.027929309,0.00530115,0.073596622,0.04470148,0.069778487,-0.009587781,-1.223465204,-1.769685191,-2.350886011,-2.815964057,0.6075080389999999,0.717202443,-8.400404692,-9.615749603,-12.27359203,-6.284553505,-9.935687675,-3.8924406510000003,-5.828385311,-2.984032047,-1435.6656982540153 -4091,4091,G239K,0.036394657000000004,-0.009619633,-1.058105408,-2.422242315,-2.8525541939999997,0.038310036,0.033558542999999996,0.039230771,0.006894531,-0.07334883099999999,0.054109565,-0.798726347,-1.317484469,-2.3954398969999997,-2.449044733,-2.501671405,-3.203436983,1.035420741,0.229645805,-10.18408251,-11.18211419,-12.71559509,-8.458586151,-10.91053208,-7.653585014,-8.190356716,-3.5246431210000004,-1432.6774800149724 -4092,4092,G239M,0.036952763,0.031896943,-1.3120523590000002,-2.402990913,-2.8667761869999997,0.109325022,0.058943199,0.014962327,0.024374446,0.022849341000000002,0.040944544,-0.995190771,-1.6289139469999998,-2.551787098,-2.2541947280000003,-2.35698861,-3.376563763,0.545870292,0.102829382,-12.80048397,-13.15707536,-16.15085905,-11.957135300000001,-11.9995137,-10.73783642,-8.647575983,-5.235175498,-1431.9532217779197 -4093,4093,G239L,-0.02939842,-0.602164272,-1.905582694,-2.1040501469999997,-2.898614068,-0.012302918000000001,-0.032824812,-0.025972027,0.017877257,-0.24944009,-0.9548884540000001,-1.779297795,-2.0318675930000003,-2.119233485,-2.088866809,-2.552823927,-3.244404208,1.063726662,-0.016636608,-12.2880638,-12.83794054,-14.78584284,-11.50994907,-12.47366219,-9.832924385,-8.058226907,-4.88891888,-1418.68828297453 -4094,4094,G239N,-0.046394232,-0.080821127,-0.062074112,-0.34396633200000004,-1.935226949,0.230407045,-0.023459942,-0.06932852099999999,-0.09949,-0.09832986099999999,-0.063312392,-0.027820214,-0.096328009,-0.095089017,-0.5928436460000001,-1.529700129,-2.340753768,0.8875397290000001,1.3348479640000002,-7.345668886,-7.8323325420000005,-10.0533922,-5.460829338,-7.662952934,-5.71883741,-5.782938698,-2.257144277,-1447.1509283902124 -4095,4095,G239Q,-0.051212267,-0.004606337,-0.60027163,-1.855041404,-2.958203478,0.070802197,-0.051690608,-0.050733925,-0.032725726000000004,-0.020488416000000002,0.011275743000000001,-0.28164555199999997,-0.9188977070000001,-1.5918730509999999,-2.1182097559999997,-2.675828164,-3.2405787910000003,1.417485572,0.788285311,-9.250107822999999,-10.18820316,-13.6929044,-7.088618812999999,-9.699257843,-5.5815549010000005,-6.663909406,-3.6406527000000004,-1436.6328143989667 -4096,4096,G239P,-0.030044671000000002,-0.788468433,-2.005819984,-2.3268610819999997,-3.013732415,-0.017026849,-0.035005921,-0.025083421,0.046021442999999995,-0.480416444,-1.096520422,-1.998481524,-2.013158443,-2.252772394,-2.40094977,-2.6222453359999998,-3.405219493,1.2970521990000001,-0.11011246400000001,-11.14717653,-10.63579541,-14.99861381,-11.46005156,-10.27268575,-8.36873613,-7.3783663,-3.7330633260000003,-1436.8369134450331 -4097,4097,G239S,-0.036318762000000004,-0.0063973419999999994,-0.040629764,-0.888703372,-2.061764239,0.35870649299999996,-0.018824063000000002,-0.05381346,0.049168518,0.004046582,-0.016841266,-0.015057124,-0.066202404,-0.265788572,-1.511618172,-1.8260621769999998,-2.297466301,1.3084350009999999,1.352249773,-8.687387048,-8.043391243,-13.61787285,-7.759276695,-6.483983467000001,-7.532410988,-6.3779146870000005,-2.595907263,-1455.8930970332585 -4098,4098,G239R,-0.022864891000000002,0.004651346,-1.069065344,-1.850444295,-2.175100285,0.025220657999999996,-0.0144523,-0.031277481,0.024959625,0.015781532,-0.00647884,-0.71787804,-1.4202526480000002,-1.779146486,-1.9217421030000001,-2.120590704,-2.229609866,3.322913849,2.0730124819999998,-8.846759003999999,-9.79658989,-12.24630949,-7.275723396,-9.936254005,-4.978918236,-6.390762218,-2.592075141,-1438.6132332244888 -4099,4099,G239T,0.0006682610000000001,0.031157401,-0.95836082,-1.971784833,-2.909216932,0.206584023,0.0016414829999999998,-0.00030496099999999997,-0.00097512,0.012907822,0.04940698,-0.5350768379999999,-1.381644801,-1.7454376740000002,-2.198131992,-2.439940888,-3.378492975,1.77124818,0.854888028,-8.362096637999999,-7.507867202999999,-13.28994987,-7.436592484,-6.364152954,-7.211920677,-7.1165542870000005,-2.331966742,-1442.4819256756455 -4100,4100,G239W,-0.049992484000000004,-0.516454345,-1.854888405,-2.104785648,-2.3449919059999997,0.051244985,-0.02385856,-0.07612640700000001,0.069411578,-0.159360076,-0.8735486140000001,-1.8524153490000002,-1.85736146,-2.253442085,-1.956129211,-2.359673592,-2.33031022,0.823901656,-0.052810498,-13.02576905,-13.61643104,-16.32357917,-12.4180429,-12.83293024,-9.937861908,-9.041201555,-5.938691254,-1435.1701678093523 -4101,4101,G239V,-0.012061086,-0.801233897,-1.868598154,-2.138702757,-2.429759452,0.032445619,-0.00247561,-0.021646561,0.101497129,-0.522029896,-1.080437898,-1.958504547,-1.77869176,-2.098372799,-2.179032714,-2.563626249,-2.295892655,1.376463075,-0.08280204099999999,-9.77251927,-10.64894082,-13.79351885,-8.636477005,-9.257847115,-6.525812561,-6.724674695,-3.51152626,-1425.0985760153271 -4102,4102,G239Y,0.054137135999999995,-0.009956839,-1.214222587,-2.2205899419999997,-2.951931816,0.058547232000000005,0.067656421,0.040617851,0.088485139,0.085813936,-0.10572761300000001,-1.193032071,-1.235413103,-1.9852654319999998,-2.455914451,-2.568618195,-3.3352454369999998,0.375886409,0.066190238,-10.54996781,-11.45608288,-14.96842617,-9.600451653,-10.84251923,-5.882359137999999,-7.2009264029999995,-3.664997576,-1441.6520297471434 -4103,4103,S240A,0.014647166000000001,0.04287168,0.011648671000000001,-0.003480665,-0.022943869,-0.003432627,0.004032195,0.025262137,-0.04204393,0.027697431,0.058045929,-0.008074391,0.031371733,-0.038474292,0.031512962,-0.032764675,-0.013123063,1.263908535,2.456590378,-2.248778029,-1.708949036,-1.904252693,-1.935560425,-2.958933159,-2.736194832,-3.015460112,0.345458359,-1454.7536486675963 -4104,4104,S240C,0.037620546,0.070984486,0.023259807,0.024609858,-0.932433747,0.17841447100000002,0.037692435,0.037548657,-0.043728504,0.072649436,0.069319536,0.026033663,0.020485951000000002,-0.016076214,0.06529593,-0.49142184899999997,-1.373445645,0.839613556,1.489518414,-9.056184189,-9.111981422000001,-8.763100463999999,-7.374000671,-11.14231943,-8.889518959,-7.31732263,-2.9090579069999998,-1449.6630066856742 -4105,4105,S240E,-0.076451975,0.059229322,0.023507772000000003,0.054374492,-0.725830676,0.054118165999999995,-0.13249650699999999,-0.020407441999999998,0.054115446,0.08768633699999999,0.030772307000000002,0.004387366,0.042628177999999996,0.017873368,0.090875615,-0.48484489,-0.966816461,0.8357402970000001,1.4909331730000002,-8.748148415,-8.666740509,-7.5302069320000005,-8.652781731000001,-10.45845785,-8.432555054,-6.027861883,-2.132577997,-1444.6841750466265 -4106,4106,S240D,-0.053387797,0.026452073,-0.027099816000000002,-0.124852755,-1.862349445,0.264060923,-0.09368,-0.013095593999999999,0.071766978,-0.007555681,0.060459827,-0.071224761,0.017025129,-0.030568436,-0.21913707300000002,-2.00480407,-1.719894819,0.8557448590000001,1.3028902820000001,-10.43915103,-10.61284664,-10.40271841,-9.27614447,-12.30038206,-9.603663574,-7.692835923,-3.852939978,-1441.621699363459 -4107,4107,S240G,0.022606177,0.023675744,-0.006154675,0.003864387,-0.030204569,0.41831645700000003,-0.023578521,0.068790874,-0.022554106,0.023016395,0.024335093,-0.045312057999999995,0.033002708,-0.012523933000000001,0.020252706000000002,-0.061926687,0.00151755,1.388676475,2.495855297,-5.092763226000001,-4.24506588,-3.365251045,-4.1400077589999995,-6.671947417999999,-7.041544029,-5.765593895,-0.8976415640000001,-1443.950700812973 -4108,4108,S240F,-0.029228062000000003,0.005170654,-0.212806845,-1.82511757,-2.1783692080000003,-0.07344552900000001,-0.033065847,-0.025390276,-0.030720493999999997,-0.009267375999999999,0.019608683000000002,-0.11597108800000001,-0.309642602,-1.728527277,-1.9217078630000002,-2.2256416569999997,-2.131096759,1.0048078040000001,0.705535844,-11.51816847,-12.23535089,-11.00720971,-9.617896446,-15.73242104,-8.997964248999999,-6.793336011,-2.558892643,-1443.4314585779794 -4109,4109,S240I,0.041438765,-0.476190251,-1.96507792,-2.212159014,-2.406031271,0.052659733,0.038363577999999995,0.044513950999999996,-0.116881094,-0.171834032,-0.780546469,-1.592484513,-2.337671326,-1.97973142,-2.4445866080000003,-2.078905791,-2.73315675,4.058217474,2.391368569,-9.741262784,-11.00340344,-10.71112164,-8.368944115,-12.24118104,-6.381663689,-5.062078138,-0.360292059,-1454.1922652469948 -4110,4110,S240H,-0.014579481000000002,0.009177225,-0.041348351,-0.005660976,-1.7967942819999998,0.005638745,-0.029473552000000004,0.00031459,-0.0465464,-0.048846336,0.067200785,-0.10432093699999999,0.021624236,-0.075866599,0.064544648,-1.620125992,-1.973462571,0.968150187,1.3345539659999999,-11.66624361,-12.01230915,-10.89983774,-8.19810537,-15.58468805,-11.63627774,-7.058853111,-3.3276634080000003,-1442.008793596644 -4111,4111,S240K,-0.006614773000000001,-0.147587833,-1.638797955,-1.735364052,-2.27872131,-0.18490237899999998,-0.022698785,0.00946924,-0.006074148000000001,0.085290478,-0.380466144,-1.71742325,-1.560172659,-1.803640161,-1.667087942,-1.9028145319999998,-2.654628088,4.274744622,2.6929237489999998,-11.83511694,-10.10433186,-9.525652115,-10.22950117,-15.12778197,-14.18831757,-7.046758199999999,-2.611570104,-1444.4992321636528 -4112,4112,S240M,-0.053300474,-0.02908226,-0.03242939,-1.9553361790000001,-2.600753429,0.013747405,-0.064077336,-0.042523610999999996,-0.124017645,0.050305117999999996,-0.10846963800000001,-0.02047205,-0.04438673,-1.207920348,-2.70275201,-2.210184705,-2.991322152,2.226515296,1.43697974,-10.78746736,-10.63642024,-9.239874648999999,-10.01712814,-14.80271816,-9.241195587,-6.232574323,-1.7052540530000002,-1457.0129698538221 -4113,4113,S240L,-0.006525895,0.012265038999999998,-1.211545501,-1.9746876,-2.888226204,-0.013294256,-0.003489258,-0.009562530999999999,-0.022362985,0.049355947000000004,-0.02482587,-1.056747773,-1.366343228,-2.015385851,-1.933989349,-2.678831653,-3.097620754,2.258446528,0.920188867,-12.04377773,-12.65058064,-11.58836924,-10.49254511,-16.40961912,-9.077774536,-7.056188848,-0.31470181399999997,-1452.6523113949224 -4114,4114,S240N,-0.106726605,-0.018215751000000002,0.031108011,-0.097609826,-0.913859267,0.055278325,-0.16656773800000002,-0.046885471,-0.017490732,-0.139649349,0.10321784699999999,-0.02722717,0.08944319199999999,-0.20158017,0.006360519,-1.057716492,-0.7700020409999999,1.5116560890000001,1.566086053,-7.758796128999999,-7.930515465,-6.3279529420000005,-5.364080521,-12.32642848,-6.845003235,-5.118234987,-2.61397371,-1445.2697137091309 -4115,4115,S240Q,-0.0092215,0.051296904000000004,0.033281614,-0.0032205479999999997,-1.606006606,0.156544485,-0.008838861,-0.009604138,-0.082614422,0.04626943099999999,0.056324375999999995,0.021529292000000002,0.045033936,0.011700727,-0.018141822,-1.527682816,-1.684330395,0.485066141,1.309037037,-11.71454063,-10.59190579,-10.631098099999999,-10.55950613,-15.18730841,-11.60288471,-6.758813166,-3.2960634719999997,-1450.2621635687537 -4116,4116,S240P,-0.012011325,-0.136174601,-1.40660669,-2.118872495,-2.7548283689999997,-0.0084976,-0.041459759,0.017437109,-0.035910033,0.012437905,-0.284787106,-1.282362413,-1.530850966,-2.115131588,-2.122613402,-2.6179982969999998,-2.891658441,0.94060404,0.096316325,-10.80836781,-10.11033876,-12.0477924,-9.181198708,-12.45706288,-10.24544629,-7.456460937999999,-3.316222515,-1451.521748711355 -4117,4117,S240R,0.004842682,-0.00639161,-1.198689776,-2.192751031,-2.648062661,-0.066925953,-0.021888533999999998,0.031573897999999996,-0.061003789,0.004082284,-0.016865504,-0.910675199,-1.4867043519999998,-2.252164615,-2.1333374469999997,-2.874217732,-2.421907589,1.8179582069999998,0.633341086,-13.88855818,-13.01731786,-14.78807972,-11.08666785,-15.87378561,-14.67693988,-6.608010375,-1.206850116,-1446.2819364639 -4118,4118,S240T,-0.017192358999999997,0.027964719,0.002360835,-0.039387726,-1.164781075,0.016033072,-0.029957951,-0.0044267659999999995,0.007286991,0.037142385,0.018787052,-0.005458825,0.010180494,-0.025979916000000002,-0.052795536,-0.896674959,-1.43288719,0.775985507,1.379658729,-2.821457811,-2.539737953,-3.4088088460000003,-2.0148983080000002,-2.857323547,-3.286520401,-3.0597334,0.6761057,-1464.0254370016046 -4119,4119,S240W,-0.019713187,-0.758188772,-2.171904949,-1.971657634,-2.353095749,-0.029746582999999997,-0.02961271,-0.009813663,-0.052197756,-0.501573151,-1.014804393,-2.6407891930000003,-1.703020705,-1.948854853,-1.994460414,-2.826180475,-1.880011022,0.258771612,-0.51517389,-14.25278716,-14.24157705,-13.91144769,-12.12958925,-17.0298372,-13.951484599999999,-8.28740065,-4.297872638,-1442.8514028098434 -4120,4120,S240V,0.032684209,0.007553882,-1.030665821,-1.7641267330000001,-2.206336385,-0.032732374,0.019903791,0.045464625999999994,-0.014043077,-0.024607969,0.039715732999999996,-0.62187966,-1.4394519819999998,-1.8999820969999999,-1.6282713690000001,-2.351338986,-2.061333784,1.865558038,0.83584986,-8.76306546,-9.826564095,-10.60326877,-7.805614471,-9.950149193,-5.6297307739999995,-4.833311757,0.496939597,-1452.9697395740077 -4121,4121,S240Y,0.075639975,0.064536737,-0.46994701,-1.4975787969999999,-2.128981685,-0.10407870699999999,0.069139836,0.082140114,-0.062555504,0.01900028,0.110073194,-0.168910993,-0.770983027,-1.4482525030000002,-1.54690509,-2.246396878,-2.011566491,1.107778403,0.7523349559999999,-11.75838981,-12.28574372,-10.59578602,-8.527073067,-15.88397907,-11.49936717,-6.59638858,-2.959096153,-1444.5960550848395 -4122,4122,R241A,0.034593009,0.033313734,0.040180392,-1.3204279490000002,-2.0916275509999998,-0.11969009300000001,0.043031812,0.026154205,-0.022570501,0.061585445,0.005042023,0.057419459000000006,0.022941324,-1.017667081,-1.6231888159999999,-1.9701186819999998,-2.21313642,3.21787308,2.42544262,-11.30024273,-13.03533869,-10.54232766,-8.91739196,-11.60693608,-12.39921925,-5.44537278,-0.956594715,-1444.358668091707 -4123,4123,R241C,-0.031404205,0.051584705999999994,0.029209912,-1.173632658,-1.452284211,-0.07890087400000001,-0.036839687,-0.025968723,-0.038881485,0.103441079,-0.000271667,0.140636075,-0.08221625099999999,-0.8733418070000001,-1.4739235080000002,-1.465641961,-1.4389264609999999,3.259127358,2.684509563,-12.85110836,-11.94312028,-11.47337929,-12.55052983,-13.47295764,-14.81555478,-7.517223018999999,-3.01295916,-1450.0705146808177 -4124,4124,R241E,0.014826033,-0.015203806,-0.42754917200000003,-1.5586590319999998,-2.959300658,-0.07513953,0.021140309,0.008511757,-0.008482633,-0.004016025,-0.026391587,-0.084706633,-0.77039171,-1.522127223,-1.59519084,-2.237666329,-3.680934986,0.919229884,0.716212843,-13.73643701,-17.51842941,-11.94104588,-11.82236833,-14.76764871,-12.63269271,-7.500102303999999,-1.6435470269999999,-1435.2255816985853 -4125,4125,R241D,0.01745611,-0.076117713,-1.165886901,-2.563756685,-2.651565275,-0.07178810099999999,0.028574369,0.00633785,-0.004502949,0.070411775,-0.22264720100000002,-1.016391305,-1.315382496,-2.424623506,-2.702889864,-2.335682423,-2.967448127,0.54153325,0.097891039,-13.64692426,-17.0015833,-14.03822873,-12.0828095,-13.38019002,-11.73180975,-7.62633047,-2.725776423,-1437.5294645982794 -4126,4126,R241G,0.011906495,0.0028577840000000004,-0.011041947,-0.380109442,-1.734141371,-0.07669516700000001,0.001028804,0.022784186,0.00800015,0.010427931,-0.004712364,-0.020604779,-0.001479114,-0.13735966900000002,-0.622859215,-1.584687182,-1.883595559,1.019141708,1.341715451,-14.65443616,-17.37099989,-13.70855297,-12.60731023,-15.52452294,-14.06079476,-7.373169421,-3.7569556019999997,-1441.044818150811 -4127,4127,R241F,-0.024787012,0.00875149,-0.64979902,-1.764842636,-3.1106708860000003,-0.095421585,-0.010697934,-0.03887609,0.005338975,0.094621499,-0.07711852,-0.279568405,-1.0200296340000001,-1.696179537,-1.833505734,-2.628427753,-3.592914018,1.1538986629999999,0.725994933,-12.43081222,-13.03544014,-10.89002439,-11.31325642,-12.6608269,-14.25451323,-6.577830232999999,-2.902312775,-1440.4860874712467 -4128,4128,R241I,-0.013066701000000002,0.015932973,-0.054218598,-1.6680823530000002,-2.126474784,-0.026963214,-0.0007030439999999999,-0.025430357,-0.011482931000000002,0.021298842000000002,0.010567103000000001,0.022650372999999998,-0.13108756900000001,-1.443025077,-1.8931396280000001,-2.308326503,-1.944623065,0.817757974,0.7182361620000001,-11.77907322,-14.17737931,-12.16146342,-10.18150935,-11.49224924,-10.88276477,-7.330785375,-2.235129835,-1443.704051590059 -4129,4129,R241H,0.019062724,0.0014060070000000001,-0.005179293,-1.064610456,-1.777018224,-0.112682724,0.04024897,-0.002123523,-0.014153836999999999,-0.005228707,0.008040720999999999,0.005682952,-0.016041536999999998,-0.8076587270000001,-1.321562184,-1.5699759919999998,-1.984060455,2.893909877,2.295703138,-8.240152638,-10.43017805,-7.779297577,-7.42847184,-7.549151527,-8.013664200000001,-7.632182704,-2.620532368,-1443.170505369082 -4130,4130,R241K,0.046051838,0.047101974000000005,-0.038313137000000004,0.023925123,-1.5078172159999998,-0.070776851,0.066664471,0.025439204,-0.0057696019999999995,0.099025827,-0.004821879,0.0016531979999999998,-0.07827947099999999,0.111394433,-0.063544188,-1.300687691,-1.7149467409999999,0.55664262,1.321871757,-8.889882747,-10.7338609,-8.043897263,-8.105034103,-9.154072029,-8.412549438,-7.757908788,-3.8462028669999997,-1442.9127959152684 -4131,4131,R241M,0.042108411,0.018826722,0.019520253,-1.6121712430000001,-1.990657395,-0.101458809,0.043545872,0.04067095,-0.01877311,0.003521629,0.034131813999999996,-0.015380142,0.054420647,-1.071644344,-2.152698141,-2.0434011009999997,-1.937913688,2.277414835,1.555363719,-10.19033618,-11.66319719,-9.187466331,-9.575750481,-9.314722145,-11.21054475,-7.056193131000001,-3.401153036,-1443.5734497080557 -4132,4132,R241L,-0.026596828,-0.018877137,-0.041630805,-1.436486669,-2.0114707480000003,-0.103056131,-0.009695376,-0.043498279,-0.024099122999999997,0.035405856,-0.07316013,0.058621803,-0.141883413,-1.25928438,-1.6136889580000002,-2.017821038,-2.005120457,2.388186356,1.595702133,-9.362577834,-10.8133187,-8.140190521000001,-7.71786599,-9.81294828,-10.32856567,-6.957559774,-2.0464285490000003,-1439.1430639489554 -4133,4133,R241N,-0.021572766,-0.013714809,-0.026788792999999998,-1.112261388,-1.992377845,-0.023699373,-0.00775863,-0.035386902000000005,-0.073720588,0.040599977999999995,-0.068029595,0.003070147,-0.056647733,-0.7047797090000001,-1.519743066,-1.7339379380000002,-2.2508177519999997,2.163906295,1.659054508,-11.32775862,-11.98449304,-11.42015608,-10.14130768,-11.41435835,-11.67847797,-5.491333458,-2.481570683,-1448.67351417616 -4134,4134,R241Q,0.054715823,0.023750611,0.035754436,-0.8995478290000001,-1.993369224,-0.079126788,0.06004499,0.049386655,-0.013291194,0.018679955,0.028821267,0.021961573999999998,0.049547297000000004,-0.518770236,-1.280325421,-1.612550991,-2.3741874569999997,1.874814006,1.556200955,-10.02741834,-10.91675191,-9.497010468,-8.860969543,-11.27398707,-9.588372688,-7.688362044,-2.649398676,-1441.3486342080869 -4135,4135,R241P,0.009473081,-1.4697481140000002,-1.673374965,-1.788275454,-2.096688393,-0.021387608,0.027353097000000003,-0.008406935,-0.046283871,-1.4062294709999998,-1.5332667569999998,-1.8024337869999998,-1.5443161419999998,-1.778066677,-1.798484231,-1.893245576,-2.30013121,0.130367061,-0.8502122440000001,-15.55998061,-16.71843114,-14.86606956,-14.96729513,-16.06903962,-15.179067600000002,-9.755191922,-6.295671412000001,-1457.5731515232474 -4136,4136,R241S,-0.013676263999999999,0.008694949,-0.014958192,-0.016257056000000002,-1.359872404,-0.078648736,-0.013136135,-0.014216393,-0.005868274000000001,0.044816022999999997,-0.027426125,0.003350428,-0.033266811,0.068785829,-0.10129994,-1.3502252869999998,-1.369519521,2.5007450980000003,2.2322910730000003,-11.78566299,-12.28126911,-9.900953857000001,-11.69757943,-11.68142487,-13.367087699999997,-5.995591737000001,-1.7728034819999998,-1448.1731463554315 -4137,4137,R241T,0.030332524,0.013484788999999999,0.015553299,-0.19138275899999999,-1.666129269,-0.087208325,0.025909782000000003,0.034755266,-0.015726962,0.034435557,-0.00746598,-0.00018056099999999998,0.031287157999999995,-0.032974881,-0.349790636,-1.5266652369999998,-1.8055933000000002,0.830430723,1.328026579,-12.09644727,-11.97427353,-11.61953421,-12.25118679,-11.65919806,-12.97804374,-5.409067245,-0.775256693,-1445.845379380975 -4138,4138,R241W,0.04206307,-0.037484847,-1.1678993340000001,-1.967444461,-2.702348336,-0.097878609,0.07026458599999999,0.013861554,-0.030770887,-0.008355020999999999,-0.066614673,-0.918142483,-1.417656185,-1.846424139,-2.088464782,-2.477642359,-2.927054312,2.348879139,1.093491084,-12.19103323,-12.44103796,-11.70186058,-10.69430461,-13.86588339,-12.25207961,-8.195255951,-4.718085304,-1439.0943491812795 -4139,4139,R241V,0.014721255,0.013310777,0.00988001,-1.4085874669999998,-2.026693096,-0.052529565,0.025116572,0.004325938,-0.033002275,0.026312062999999997,0.00030949,0.06717466799999999,-0.047414649,-1.244250324,-1.57292461,-2.10955175,-1.9438344419999998,2.320028209,1.5172927319999998,-11.73726063,-12.99162476,-11.53285156,-10.56671231,-12.88388171,-10.71123279,-6.440676297,-1.4971511530000001,-1453.4891619486734 -4140,4140,R241Y,-0.0069655509999999995,0.012177525,-0.962852965,-2.0099403319999998,-3.1178274910000003,-0.079916174,0.024028992000000002,-0.037960094,0.006576927,0.053163017,-0.028807968,-0.6833810290000001,-1.242324901,-1.772671645,-2.247209019,-2.81406433,-3.4215906510000003,1.894122131,0.8732641790000001,-12.27465176,-15.67427855,-12.71191299,-11.50034962,-11.00994752,-10.47677013,-7.183835805,-1.982449093,-1440.1206082110293 -4141,4141,G242A,0.019968479,-0.019883981999999998,0.0034657570000000003,-0.012514385,-0.296453177,0.034622018,0.008288929,0.031648027999999995,-0.017195342,-0.041342647999999996,0.001574684,-0.006063122,0.012994635,-0.044027422000000004,0.018998653,-0.161698342,-0.431208011,1.5339614240000001,2.270422064,-2.9231305539999997,-3.6990882419999997,-2.718300697,-3.153576599,-1.6307879330000001,-3.4138992999999993,-3.486783934,-0.8348919509999999,-1444.3775380570441 -4142,4142,G242C,-0.02794067,0.08428548599999999,-0.071635801,0.035396777000000004,-2.027301849,0.022479061,-0.083980921,0.028099581000000002,0.032736981,0.030142687999999997,0.138428283,-0.11810937,-0.025162232000000003,0.041935738,0.028857816,-1.577884443,-2.4767192540000003,0.58790787,1.311444705,-9.484352937,-9.436618805,-10.033762699999999,-10.03131647,-7.9762073970000005,-9.943859314,-6.216412279,-1.000176927,-1446.3981176251546 -4143,4143,G242E,0.047079483,-0.7091781909999999,-1.947909869,-2.019097557,-3.223613025,-0.044543503,0.033582851000000004,0.060576115,-0.038405924,-0.319931994,-1.098424388,-2.1888682619999997,-1.706951475,-2.135023243,-1.9031718709999998,-2.8585928610000004,-3.588633189,0.593214537,-0.35953710899999997,-11.97965085,-12.08102246,-10.13479467,-12.97929693,-10.68766671,-14.01547349,-9.36387064,-7.989895928999999,-1428.0024187099189 -4144,4144,G242D,0.059654078,-0.927510732,-2.293886831,-2.263309766,-2.669919713,-0.01547825,0.069329991,0.049978165,0.037529243999999996,-0.5763264220000001,-1.278695042,-2.359726994,-2.228046668,-2.430820712,-2.095798819,-2.552330339,-2.7875090869999997,0.331494165,-0.517508637,-10.07526339,-10.37248876,-9.819390106,-10.5269671,-8.807720558,-10.84975043,-5.765351645,-2.240308421,-1446.2163212876767 -4145,4145,G242F,0.012458878999999999,-1.6620958259999998,-2.077613387,-2.256600975,-3.052286547,-0.057445046,0.027524911000000003,-0.002607153,-0.06819708099999999,-1.7650419019999999,-1.55914975,-1.98318513,-2.172041643,-2.531400102,-1.9818018469999998,-2.652909729,-3.451663365,-0.17197271,-1.082036255,-17.54349386,-15.40505966,-19.95554143,-18.272968600000002,-16.59588768,-17.48801191,-9.36387064,-7.989895928999999,-1449.9249160424806 -4146,4146,G242I,0.039835043,-1.480163282,-2.669445131,-2.459357094,-2.8324936469999997,0.027044502,0.033520744,0.046149342,-0.041395976,-1.2440151609999999,-1.7163114030000002,-2.416400899,-2.922489362,-2.487494617,-2.4312195709999997,-2.3079742480000003,-3.357013045,0.44679917799999996,-0.749588788,-13.79686815,-12.73304449,-16.51981239,-14.14848635,-11.27984464,-14.30315286,-6.692846389,-2.969460901,-1431.0874009695835 -4147,4147,G242H,-0.017238353,-0.022541111000000003,-1.209522301,-2.04438682,-3.045159625,0.071388884,-0.036087599,0.001610893,0.038690591,0.044383127,-0.08946534800000001,-1.0119092809999999,-1.40713532,-1.912306772,-2.1764668680000003,-2.63587639,-3.45444286,2.268281116,0.9791622190000001,-11.34400576,-7.7227354429999995,-11.96367124,-11.89716888,-9.193399857000001,-15.94305336,-5.206718582,1.0358307070000001,-1446.4309090874158 -4148,4148,G242K,-7.269999999999999e-05,-1.9372397419999998,-2.355990324,-2.534977912,-2.908114465,-0.018763095,-0.00621108,0.006065645,-0.043322491,-2.401221076,-1.4732584080000002,-2.193395572,-2.518585075,-1.963459294,-3.10649653,-2.3859989169999998,-3.430230012,-0.589308439,-1.164380424,-13.38763742,-12.3456992,-12.36858765,-13.93809781,-11.90908575,-16.3767167,-9.36387064,-7.989895928999999,-1437.2629339243285 -4149,4149,G242M,-0.030341482000000003,0.021814165,-1.240125203,-2.645899357,-3.01903591,0.006358096999999999,-0.027297542999999997,-0.033385421,-0.037822109,0.056765168,-0.013136838999999999,-0.818520868,-1.6617295369999998,-2.328947279,-2.962851435,-2.450456906,-3.587614913,0.7695754690000001,0.16286388400000001,-13.66170345,-13.12341527,-14.96220249,-14.58538364,-11.81028213,-13.82723373,-6.794746247000001,-2.6263973309999997,-1446.56990550505 -4150,4150,G242L,0.004138069,-1.8057455880000002,-2.258671369,-1.9605377019999999,-3.304678282,0.031867696,-0.01505875,0.023334887999999998,-0.047946347,-2.027219075,-1.584272101,-2.421453562,-2.095889175,-2.015426025,-1.905649379,-3.011996916,-3.5973596469999998,-0.530072135,-1.145908084,-13.42630293,-11.171926800000001,-14.45627978,-15.15536514,-12.61768926,-13.73025369,-5.95038209,-2.416103581,-1435.3116423771717 -4151,4151,G242N,0.050680058,0.05806449599999999,0.023493532,-1.443334135,-2.883240142,-0.006618384000000001,0.044711376,0.056648739000000004,-0.105273165,0.063219147,0.052909844000000004,0.171108183,-0.124121119,-1.152231585,-1.734436684,-2.477861195,-3.288619088,0.43506133,0.711720285,-5.4519826810000005,-3.8917257610000004,-5.487293739,-5.437034232999999,-3.4830976560000004,-8.960762016,-3.147978094,2.092658447,-1458.1989530478604 -4152,4152,G242Q,-0.038406096,-0.065172092,-1.555720351,-2.43797803,-2.811114583,0.049681324000000006,-0.02452216,-0.052290032,0.026989932,0.014902721,-0.145246905,-1.3741921259999998,-1.737248575,-2.37470477,-2.5012512890000003,-2.4962143969999997,-3.126014768,0.49666654200000004,0.048585479,-12.96810395,-11.38536564,-11.69882542,-14.47567482,-10.96360384,-16.31705,-8.042506457,-4.853139761,-1437.701170094777 -4153,4153,G242P,0.019894371,-1.6267619530000001,-2.2777156659999998,-2.3339217430000003,-2.566195875,0.012166202,-0.012963742,0.052752484,-0.03788816,-1.629393219,-1.624130686,-2.1785296659999998,-2.376901665,-2.39575142,-2.272092065,-2.517261047,-2.615130703,-0.30166681100000003,-1.048345528,-12.46006301,-12.32502893,-12.48947481,-13.10456232,-11.23329959,-13.14794939,-9.36387064,-7.989895928999999,-1452.902841620613 -4154,4154,G242S,-0.0021627179999999997,0.007008101,0.019852939,0.032287125,-1.0115331779999999,-0.046007477000000005,-0.013968507,0.009643071999999999,0.007749151,0.038450381,-0.024434179,0.041444194,-0.0017383160000000002,0.040137128,0.024437121000000003,-0.590491845,-1.4325745109999999,0.7217375690000001,1.418405045,-3.046935623,-3.8234070210000004,-2.267185654,-3.589347816,-2.286620132,-3.268117493,-2.974873642,-0.12341295099999999,-1447.5252785808407 -4155,4155,G242R,-0.0036276040000000004,-1.7439139769999998,-2.060574002,-2.233552101,-2.6985392139999997,-0.022736546,-0.027984123,0.020728915,-0.089629304,-1.873896281,-1.6139316730000002,-2.025092719,-2.096055285,-2.12837112,-2.338733082,-2.322431415,-3.074647012,-0.46698059399999997,-1.1258706859999998,-15.96982515,-12.3164422,-15.973057500000001,-17.72762822,-13.79948146,-20.03251639,-9.356225304,-7.961305169,-1432.2485214704648 -4156,4156,G242T,-0.006713652,0.0030825709999999997,-1.225077446,-2.064022705,-2.8794625480000002,0.072060647,-0.028665889,0.015238585,-0.058683578,0.040678883,-0.034513742,-0.795455563,-1.654699329,-2.052185858,-2.0758595509999997,-2.474725481,-3.284199615,1.9198680419999998,0.7806599479999999,-7.478744797,-8.172118492000001,-6.9020060270000005,-8.721787788,-5.0872030939999995,-8.510608582,-5.710115312999999,-1.7639181780000002,-1435.1830131234601 -4157,4157,G242W,-0.011548181999999999,-1.703825526,-2.127367915,-2.745488706,-2.9346368660000004,0.058779047,-0.00737699,-0.015719373999999998,-0.087303071,-1.7844378280000002,-1.623213223,-2.178672315,-2.076063515,-2.5507960290000002,-2.940181382,-2.973335651,-2.89593808,-0.326238774,-1.113085917,-16.00344075,-13.87773368,-16.07976348,-17.68528578,-14.60468019,-17.76974064,-9.36387064,-7.989895928999999,-1450.1642168797553 -4158,4158,G242V,-0.033050471,-0.531326134,-1.790027489,-2.381803028,-2.889362236,0.028155857000000003,-0.034184946,-0.031915996,0.028551122999999998,-0.238196562,-0.824455705,-1.776832266,-1.8032227109999999,-2.200108502,-2.563497553,-2.92367812,-2.855046352,1.134900611,0.004831487,-10.58243262,-10.00744237,-13.78068269,-10.74166592,-7.499488815,-10.88288329,-6.090385576,-2.019193853,-1435.3470352934673 -4159,4159,G242Y,0.09374505400000001,-1.6742493219999999,-1.911044105,-2.411758032,-2.983864589,0.016863656,0.091193137,0.09629697,-0.058390713,-1.8663835290000002,-1.482115114,-1.9595880209999998,-1.862500188,-2.507802994,-2.315713069,-2.629312621,-3.3384165560000003,-0.269042314,-1.097512604,-17.6006721,-14.701102599999999,-20.80925384,-17.02177246,-15.33553066,-20.13570096,-8.090244589,-4.853139804,-1448.0816300474107 -4160,4160,I243A,0.065622234,0.07417012,0.08997634199999999,-1.181735294,-2.057418444,0.014191134,0.043586543,0.087657925,-0.024912074,0.092165237,0.056175002,0.073365698,0.106586986,-0.651611478,-1.71185911,-2.012649241,-2.102187646,1.8099466530000001,1.414766885,-10.30169086,-12.31451107,-8.785876099,-8.837180855,-11.41756712,-10.15331918,-5.483169159,-1.9379720409999999,-1439.4791851588525 -4161,4161,I243C,0.065508991,0.088783178,0.058582678,0.009597641,-1.059116701,0.017647977,0.053221397000000004,0.077796584,-0.044899344,0.12750620699999998,0.050060149000000005,0.052110980999999994,0.065054375,-0.008715603,0.027910885,-0.758953125,-1.3592802769999999,1.043947005,1.470494542,-10.66389914,-12.30887901,-9.40971521,-11.06627554,-11.34629003,-9.188335899,-7.057477235,-3.902990463,-1444.2995559587143 -4162,4162,I243E,0.010596776,0.055199009,0.0047371240000000005,-1.500954022,-2.4380046159999997,-0.038913062000000005,-0.022565222000000003,0.043758774,-0.022663985,0.10223019900000001,0.008167819,0.08676797300000001,-0.077293726,-1.44625532,-1.5556527230000001,-2.195835317,-2.680173915,1.03330992,0.742310715,-11.11002178,-12.71423007,-9.433608527999999,-11.78301006,-11.96503222,-9.654228027,-5.128931042,1.067602656,-1432.7179145086557 -4163,4163,I243D,0.037478648999999996,0.069273607,-0.690027728,-2.004955286,-2.565342048,-0.036323824,0.015904704,0.05905259400000001,-0.071348492,0.039426436,0.099120777,-0.372756662,-1.007298793,-1.978679383,-2.031231189,-2.126199389,-3.0044847060000004,1.411111592,0.7080829129999999,-8.771093701,-9.641717232000001,-6.780879417,-9.736708427,-11.33588622,-6.360277214,-4.984538349,2.980735268,-1440.6534395203926 -4164,4164,I243G,0.043449277,-0.656726809,-2.061737318,-2.372592318,-2.7513086319999998,-0.011737646000000001,0.026099373,0.060799180999999994,-0.00490937,-0.354050959,-0.959402658,-2.16004255,-1.9634320859999999,-2.206777082,-2.538407554,-2.8136895760000002,-2.688927688,0.660499126,-0.347066547,-13.17959777,-15.45428394,-11.97690398,-12.86204861,-14.14493487,-11.45981747,-6.777238499,-2.501576655,-1433.379044231493 -4165,4165,I243F,-0.036396198,0.020919039,0.023807677000000003,-0.15897730300000001,-1.5285328219999998,-0.073707766,-0.048921208,-0.023871187999999998,-0.062669146,0.069878272,-0.028040195,0.023750298,0.023865055,-0.012670095,-0.30528451,-1.5426228030000002,-1.514442841,0.7817656159999999,1.323995183,-7.970815227,-10.08807221,-7.357606613,-8.548718833999999,-7.072960983,-6.786717491,-7.051944519,-4.36075388,-1447.4451672607102 -4166,4166,I243H,0.00770152,0.032771047000000005,-0.692595712,-1.755779025,-2.491182057,-0.016622801,-0.011706175,0.027109215,-0.04959073,0.044588067,0.020954026,-0.39788886700000003,-0.987302557,-1.784609638,-1.726948411,-2.171011734,-2.81135238,1.1707611359999999,0.715058381,-10.7512672,-11.56876872,-9.46884922,-12.56076768,-10.41082461,-9.747125755,-6.733645504,-1.9833954409999999,-1436.6003255997784 -4167,4167,I243K,-0.035572865,-1.4525577840000001,-1.8964555419999998,-2.493893114,-2.7047948739999996,0.01113251,-0.043800902999999995,-0.027344826000000003,-0.10527840699999999,-1.670686839,-1.234428728,-1.9800562469999998,-1.812854837,-2.40700202,-2.5807842080000003,-2.457612014,-2.951977733,-0.10823725,-1.065455235,-11.83710142,-14.19486761,-9.431663863999999,-11.97578048,-12.03066524,-11.55252988,-8.947197447999999,-7.524563701,-1446.7747049015015 -4168,4168,I243M,0.04291108,0.037125802,0.06900585099999999,0.02935891,-1.109995239,-0.028641449,0.05057684,0.03524532,-0.066469587,0.096239836,-0.021988233,0.063475824,0.074535878,0.101519386,-0.042801567,-1.174646018,-1.04534446,0.700773883,1.341121153,-8.295955888,-8.799234001,-7.841176262,-8.811511292,-8.947658599999999,-7.080199287,-8.880794452,-7.311895812,-1451.0187727590092 -4169,4169,I243L,0.040114778999999996,0.068840548,0.073224285,0.013945488,-0.076638868,0.013247662,0.028258303999999998,0.051971254,-0.018048194,0.08542904300000001,0.052252052,0.038278415,0.108170155,0.004113932,0.023777044,-0.056668894000000004,-0.09660884199999999,1.325898485,2.473707264,-4.608048601,-4.2178633880000005,-4.570081276,-5.371840294,-4.816556389,-4.063901657,-5.2709473430000005,-2.301809001,-1458.439812200144 -4170,4170,I243N,0.021870122000000002,-0.004364141,-0.761701438,-2.137489569,-2.7810420419999997,-0.002352431,-0.001547004,0.045287247,-0.031857315,0.022453622000000003,-0.031181904,-0.438886014,-1.084516862,-2.125107035,-2.1498721030000003,-2.652838283,-2.9092458,1.4798569469999998,0.674675713,-7.169994658999999,-8.375653969,-6.240229622,-7.660734131,-7.475560852,-6.097794724,-4.513948793,-0.91189504,-1431.0041242609732 -4171,4171,I243Q,-0.045078029000000006,0.012335843999999999,-0.0154672,-1.780074959,-2.610417763,0.007899545,-0.09566188699999999,0.005505829,-0.037903951,0.036352231,-0.011680543,-0.004829987,-0.026104412999999996,-1.724585425,-1.8355644930000001,-2.076225414,-3.144610112,0.690522931,0.687069492,-11.80638272,-13.30653812,-10.25005946,-13.09220164,-10.78431976,-11.59879461,-8.086470935,-4.974837553,-1439.444557536859 -4172,4172,I243P,0.051477898,-1.593185545,-2.230320158,-2.301918801,-2.686522533,-0.00279647,0.026213259,0.076742537,-0.081950753,-1.655464765,-1.530906325,-2.447284261,-2.013356054,-2.12950254,-2.4743350619999998,-2.674962555,-2.69808251,-0.087591647,-1.061373189,-13.5438329,-15.35888942,-13.05350346,-13.50056636,-13.96186192,-11.84434332,-8.947197447999999,-7.524563701,-1462.2885100301355 -4173,4173,I243S,0.013539913999999998,0.040877079,-0.936215331,-2.158444828,-2.7778265280000003,-0.002765089,0.00015709399999999998,0.026922734,-0.06904674,0.057538695,0.024215463,-0.570250618,-1.302180043,-1.9502308480000001,-2.366658807,-2.3476283280000003,-3.2080247269999997,1.702379962,0.7668664559999999,-10.75295923,-12.50100073,-10.43171204,-10.67010694,-11.55284229,-8.609134125,-6.919913987999999,-2.979832094,-1434.1414491734467 -4174,4174,I243R,0.013166849,-1.329316832,-1.985501269,-2.492894051,-3.5119460260000004,-0.02233366,-0.015959624,0.042293322,-0.070903566,-1.240909277,-1.4177243869999998,-1.956651862,-2.014350676,-2.53486531,-2.450922792,-2.886505299,-4.137386752,0.660023241,-0.715719507,-13.54566162,-14.67477096,-12.78254327,-13.92391099,-13.24186958,-13.10521329,-8.947197447999999,-7.524563701,-1445.6039492259733 -4175,4175,I243T,0.034700401,0.043387199999999994,0.07718544,-1.090716959,-1.727102205,-0.045848094000000006,0.012469257,0.056931545,0.004101212,0.058865654,0.027908746,0.050870782999999996,0.103500097,-0.701543817,-1.4798901009999998,-1.779212043,-1.674992367,2.026990105,1.5635715890000002,-9.095602695,-10.35768358,-7.693920609,-8.577382683,-10.36173849,-8.487288109,-6.122047185,-3.114581649,-1439.7303832918406 -4176,4176,I243W,0.036021199999999996,0.044776381,0.052939125,-0.902338249,-1.790956755,-0.045507097999999996,0.008129009,0.063913391,0.0013362920000000002,0.065473542,0.024079219,-0.004810122,0.110688372,-0.646135766,-1.158540731,-1.7544518930000002,-1.827461616,1.9481741719999999,1.535148341,-11.71498308,-13.48342937,-11.42175362,-12.19147546,-11.40541675,-10.07284021,-8.947197447999999,-7.5245637,-1450.5771999093704 -4177,4177,I243V,0.025321068,0.025203681000000002,0.068278409,-0.022591264,-0.035947545,0.005088205,0.001635023,0.049007112,-0.032580653,0.04322553,0.007181831,0.036820618,0.099736199,-0.029657972,-0.015524556,-0.058302447,-0.013592642,1.233653721,2.383984478,-3.7492432630000003,-4.151168633,-3.834317978,-2.955548965,-4.1958099980000005,-3.609370743,-4.6282772539999995,-1.73228398,-1457.107880906202 -4178,4178,I243Y,0.030213179,0.027129393999999998,0.026286507999999997,-0.07660408,-1.3836478319999999,-0.09815491400000001,0.024000491000000002,0.036425867,0.054430975,0.061747537000000005,-0.007488749,-0.039668065,0.09224108,-0.06284801,-0.090360149,-1.478505304,-1.288790359,0.666937432,1.320370207,-9.338147717,-11.66803503,-8.665228439,-10.23079481,-8.291348976,-7.835331329,-7.536271033999999,-4.698523722,-1436.4941566488706 -4179,4179,I244A,-0.007152378,0.015890875,-0.021977887999999998,0.020203052,-1.073623609,-0.007154087,0.005187907,-0.019492663,-0.043698343,0.051190389,-0.019408639,-0.00179777,-0.042158006,0.032808696,0.007597408000000001,-0.654165896,-1.4930813219999999,0.785748695,1.4213444290000001,-5.330614505,-7.073929871,-5.4577110520000005,-5.636134682000001,-3.745444527,-4.739852394,-3.1532906689999995,-0.405714426,-1455.8983026426286 -4180,4180,I244C,0.022641424,0.001546656,-0.031098224,0.040619194,-0.823006157,-0.0489674,0.020656512,0.024626335,0.077993903,0.036028943,-0.032935631,-0.0014413370000000002,-0.060755110999999994,0.023903922,0.057334465,-0.290490035,-1.355522279,1.170555458,1.81393943,-8.82075938,-11.21163763,-9.454452446,-9.642571991,-7.241193375,-6.553941452,-5.659179802000001,-2.59414956,-1453.1546396207996 -4181,4181,I244E,0.016434433999999998,-0.644728313,-1.918909803,-2.48572108,-2.880303607,-0.024096356,0.011015863999999998,0.021853004,0.016390416,-0.260257373,-1.029199253,-1.7334835830000002,-2.104336022,-2.689170486,-2.282271674,-2.515447804,-3.2451594089999998,1.15172731,0.016717607,-11.62730782,-13.93446906,-12.45063636,-11.50719923,-10.28237143,-9.961863022000001,-9.082265126,-9.173498397000001,-1444.178456470836 -4182,4182,I244D,0.077135049,-1.534247897,-2.518009859,-2.175049168,-2.7457229539999997,-0.022702572,0.103359905,0.050910193,-0.050150074,-1.5746128469999998,-1.493882946,-2.160878571,-2.8751411460000003,-2.08853675,-2.261561586,-2.215844064,-3.2756018439999997,-0.025506762000000002,-0.996070606,-11.58581791,-14.28138889,-12.26633394,-11.42788671,-9.989764037999999,-9.963715965,-9.109593716000001,-9.367374332,-1448.0628876783885 -4183,4183,I244G,0.001152148,-0.062283497,-1.3015287420000001,-2.068622095,-2.384993055,-0.023535357000000003,0.008713865999999999,-0.00640957,0.027617265,-0.019775527,-0.104791467,-1.073995967,-1.5290615159999998,-2.1043164869999997,-2.032927702,-2.263808484,-2.506177625,3.218408153,1.7470941009999998,-10.79211838,-13.30399988,-10.74251078,-10.96663734,-9.227958145,-9.719485764,-6.216840116,-2.7222463,-1446.0044535812922 -4184,4184,I244F,0.043547304,-0.004534079,-0.029161945,-1.268914626,-2.43572497,-0.034944849,0.077751729,0.009342878,0.035241372,-0.008531188,-0.000536969,0.016878848000000002,-0.07520273799999999,-1.003646614,-1.5341826369999998,-1.998715953,-2.872733986,2.22480963,1.557580615,-9.703467154,-12.4180079,-10.29370527,-10.69897815,-7.372225693,-7.734418762000001,-6.0681927920000005,-4.065093317,-1455.485849021934 -4185,4185,I244H,0.0037530420000000003,-0.7866783759999999,-2.636017682,-2.244601985,-2.599593889,-0.008844934,0.017166831,-0.009660746999999999,0.037324323,-0.438617871,-1.1347388809999999,-2.200974854,-3.0710605089999996,-2.07748051,-2.411723459,-2.681909079,-2.517278698,0.601104304,-0.412550146,-11.08668098,-13.17637355,-12.00241818,-12.18982189,-8.961529694,-9.103261604,-7.911028932000001,-6.927088599,-1453.9505776548758 -4186,4186,I244K,-0.02316096,-1.5458608619999998,-2.4160009330000003,-2.0017064909999998,-3.095259022,-0.108309821,-0.03658313,-0.00973879,-0.013396587,-1.506953515,-1.584768208,-2.5191879719999997,-2.312813894,-1.872814882,-2.130598099,-2.699092201,-3.491425842,-0.025066021,-0.966104585,-11.21553403,-13.69153101,-11.85655478,-11.18525734,-9.484025878999999,-9.860301125,-9.109593716000001,-9.367374332,-1454.8025107705034 -4187,4187,I244M,0.004732867,-0.017520999,-0.022535777000000003,0.047888535999999995,-0.239541728,-0.052784062,0.029457992000000002,-0.019992259,0.094683491,-0.028973775,-0.006068223,-0.030251113,-0.01482044,0.054231879000000004,0.041545192,-0.170257648,-0.308825807,1.47996285,2.272949046,-6.47940029,-6.870320037999999,-7.225805115,-7.710339478,-5.894047714,-4.696489105,-5.465041645,-3.0150450139999996,-1460.068383490201 -4188,4188,I244L,0.046837547,0.030961462999999998,0.011056081,0.049687138,-0.235075165,-0.025678896,0.051939384000000005,0.04173571,0.054941923,0.031084577999999998,0.030838347999999998,0.02171899,0.000393171,0.037747623,0.061626652000000004,-0.120817384,-0.349332945,1.46857067,2.446598589,-5.530726764,-7.048837624,-6.882675598,-6.972667191,-3.5730005869999997,-3.17645282,-4.8571294510000005,-2.448799601,-1461.813855289016 -4189,4189,I244N,-0.0013667470000000002,0.008084051,-1.284721924,-2.24855002,-3.3332381669999998,-0.030392407000000003,0.024332696,-0.027066188999999997,0.025841241,0.06904329299999999,-0.052875192,-0.950140023,-1.619303825,-2.318007373,-2.179092666,-2.9224359410000003,-3.744040392,0.5694429,0.11314909,-9.195430228,-11.51191214,-11.37822757,-8.754122459,-6.714432662999999,-7.618456306000001,-6.070973019,-5.441105982000001,-1448.699854759965 -4190,4190,I244Q,0.050085889,-0.592769631,-2.0106955330000003,-2.59640109,-3.141498615,0.013850338,0.054863657,0.04530812,0.030508899,-0.26800979399999997,-0.917529467,-2.1095480230000003,-1.9118430419999999,-2.338236197,-2.854565983,-2.766573507,-3.516423722,0.7266717979999999,-0.260870819,-11.45010705,-14.0516451,-12.35722339,-11.63461196,-9.485426033,-9.721628761,-9.109593716000001,-9.367374332,-1452.1627177810296 -4191,4191,I244P,-0.007786819,-1.824367883,-2.21946468,-2.4812614969999998,-3.225329025,-0.007815304,0.011786804,-0.027360441,-0.03921509,-1.7442487430000002,-1.9044870230000002,-2.455453204,-1.983476155,-2.383111383,-2.57941161,-2.811448692,-3.639209358,-0.58165319,-1.094030348,-12.10081551,-14.12447701,-12.96553632,-12.38819677,-10.63211231,-10.39375515,-8.830916916,-8.120035386,-1458.4439318999648 -4192,4192,I244S,0.035562922000000004,0.007599284,0.00403651,-1.519546852,-2.244336833,-0.042046263,0.05444075599999999,0.016685088,-0.01085512,-0.00900249,0.024201057999999998,0.023761288,-0.015688268000000002,-0.950795761,-2.088297943,-2.14600331,-2.342670355,2.02707648,1.41150632,-7.911682765,-9.834381706,-8.772996407,-8.505118156,-6.207642365,-6.238275192000001,-6.130250406,-2.296846334,-1446.382653682027 -4193,4193,I244R,-0.0008085939999999999,-1.702959251,-1.995138008,-2.350243011,-2.6378856269999997,-0.033758368999999996,-0.00348903,0.001871842,-0.059515648,-1.7712347940000002,-1.634683708,-2.156585675,-1.83369034,-2.31832706,-2.382158962,-2.512581163,-2.7631900910000002,-0.141702847,-1.078846315,-11.99298197,-14.94713016,-13.10632375,-12.14341821,-9.883784149,-9.884253601000001,-9.109593716000001,-9.367374332,-1452.4749361169524 -4194,4194,I244T,0.029200261,0.051152921,0.003171942,0.091515372,-1.26337091,-0.05122391900000001,0.035183048,0.023217474,0.009238788000000001,0.07896627,0.023339572000000003,0.014300073,-0.00795619,0.094733094,0.08829765,-0.76383774,-1.76290408,0.595264548,1.3678763109999998,-4.364479523,-5.54005381,-4.788003777,-4.6121778110000005,-2.760399467,-4.121762749,-3.85947255,-2.191479522,-1453.5521386414766 -4195,4195,I244W,0.007254213000000001,-1.4891335369999998,-2.026848198,-2.38640492,-3.007136282,-0.022107402999999998,0.024142413999999997,-0.009633989,0.020651806,-1.4891207380000002,-1.489146336,-2.075386462,-1.978309933,-2.7300433689999997,-2.0427664709999998,-2.857350683,-3.156921881,-0.20834207100000002,-0.928859125,-11.85298989,-15.12816426,-13.09668448,-12.31070995,-9.820599876000001,-8.908790886,-6.770993869,-4.318748962,-1455.1393705136143 -4196,4196,I244V,0.063351737,0.047562497999999995,0.007922957,0.07763918,0.041399423,-0.026606962,0.062326458,0.064377015,0.068438873,0.035430723,0.059694273,0.02104629,-0.005200376,0.055550563,0.099727796,0.026473977000000003,0.05632486900000001,1.358406575,2.9765883360000003,0.06944684400000001,-0.20368866,0.328452095,0.09578040300000001,0.20087258100000002,-0.074182198,-0.296350994,0.236958621,-1468.1778261903673 -4197,4197,I244Y,-0.017399841,-0.059205373,-1.3136794440000001,-1.9207722109999998,-3.36554001,-0.008005634000000001,-0.027993075,-0.006806606,0.01803603,0.013910292,-0.132321038,-1.142467607,-1.48489128,-2.08901113,-1.7525332919999999,-2.9944696939999997,-3.736610326,0.689531227,0.09432728,-10.384710499999999,-13.83162063,-11.2075121,-10.35086505,-7.809050262,-8.724504471,-5.571866729,-4.047612026,-1447.0289679584093 -4198,4198,A245C,0.026716313,0.030424905,0.007611765,0.020032078000000002,-0.134037041,-0.023658857000000002,0.027944385,0.02548824,0.063362729,0.020861148,0.039988662,0.000858547,0.014364983000000001,0.032074187000000004,0.007989969,-0.064102045,-0.20397203600000002,1.271284413,2.378906169,-8.280635352000001,-8.072900391000001,-8.407343369,-7.777071205,-7.5572366870000005,-9.588625107,-7.746832232999999,-5.583922503999999,-1447.6559425694868 -4199,4199,A245E,0.052144564000000004,-1.304509822,-2.0636459819999997,-2.549644364,-2.425668012,-0.033795361,0.05629798,0.047991147000000005,0.041503252000000004,-1.382353775,-1.226665869,-2.180048298,-1.947243665,-2.544468712,-2.554820016,-2.640028486,-2.2113075369999997,-0.229231438,-0.86496871,-8.865486498,-9.254937469,-8.337445999,-8.425584236,-8.869430679,-9.440034103,-7.673697889,-5.014784325,-1445.3251546677202 -4200,4200,A245D,0.006957808,-1.647670435,-1.908391619,-2.555499648,-2.9315232960000004,-0.040542363,0.01906998,-0.005154364,-0.04347807,-1.880599898,-1.414740972,-1.833196382,-1.983586855,-2.440654844,-2.6703444519999997,-2.837244613,-3.025801978,-0.25912604,-1.1018313290000001,-10.20247545,-10.33106832,-10.15113739,-9.822253212,-10.33091506,-10.37700326,-8.765330151,-7.222716351,-1442.8509272355586 -4201,4201,A245G,0.007907824,0.000479785,0.004598097,0.002255979,-0.15004261900000002,-0.01656004,0.004370293,0.011445355,0.015190296,-0.012942094,0.013901664,-0.017010551999999998,0.026206746,0.016755498,-0.01224354,-0.09794520599999999,-0.20214003100000003,1.4439622930000002,2.410744747,-3.663431198,-3.319562141,-2.9188684460000003,-4.413447273,-4.360414604,-3.304863525,-3.954464621,0.433668811,-1453.8463276769035 -4202,4202,A245F,-0.008573186,0.001549465,-0.524997786,-2.121180393,-2.347673839,-0.052705999999999996,0.009325418,-0.02647179,0.001853564,0.001055301,0.002043629,-0.20362736,-0.8463682109999999,-1.762480489,-2.479880297,-2.0470964990000002,-2.648251179,1.50475954,0.782130826,-9.570575224,-10.66743808,-10.57867436,-8.785353249,-7.523918472,-10.29749196,-7.751663793,-5.2272882880000004,-1445.1929986649193 -4203,4203,A245I,-0.007885645,0.019592134,-0.9960241329999999,-1.908029112,-2.672161135,0.005113625,0.017004637,-0.032775927,0.005290230999999999,0.034540483,0.004643784000000001,-0.616882412,-1.3751658530000002,-1.859968214,-1.95609001,-2.38149672,-2.9628255489999997,2.12363396,0.99153588,-9.952998331,-10.73467154,-11.18321612,-8.322279922,-8.030671814,-11.49415226,-7.364562094,-5.302274699,-1451.7920164791867 -4204,4204,A245H,-0.052815544000000006,-1.645760074,-2.3479245580000003,-2.532892944,-3.24953721,-0.063438776,-0.052630434000000004,-0.053000654,-0.050140215999999994,-1.5872341209999998,-1.704286026,-2.685958641,-2.009890474,-2.448319063,-2.617466825,-2.8449088319999998,-3.654165588,-0.042650508,-1.026225934,-10.65694945,-10.56567274,-10.67927341,-9.526103432000001,-9.921352234,-12.59234542,-9.622734055,-9.90718017,-1446.8829342392273 -4205,4205,A245K,0.010416909,-1.3264582520000001,-2.4344102380000003,-2.5313329959999997,-2.7083866389999995,-0.019237367,0.036953066,-0.016119248,-0.08534946199999999,-1.2990946159999999,-1.3538218869999998,-2.175970386,-2.69285009,-2.239360804,-2.823305187,-2.334920578,-3.0818526989999997,0.351892091,-0.814459134,-10.57110859,-10.47136937,-10.54830146,-9.505665047,-10.131068800000001,-12.19913829,-9.622734055,-9.907180413999999,-1449.1445791581646 -4206,4206,A245M,-0.006193753000000001,0.008081959,0.00342815,-0.769124127,-1.93600713,-0.032434364,-0.012203189,-0.000184316,0.083192423,0.010794393999999999,0.005369523,0.005409625,0.001446675,-0.257211856,-1.281036397,-2.178846432,-1.6931678280000002,1.453140967,1.311852424,-9.470419117999999,-10.19009364,-10.33469344,-9.174012428,-8.288693047,-9.364603035,-7.9353169470000005,-5.63266955,-1452.9441580423154 -4207,4207,A245L,0.0019079379999999999,-0.021573192999999997,-0.017939827,-1.660930373,-2.375076616,-0.05711220400000001,0.012932292,-0.009116417,0.018198117,-0.031991857,-0.011154529,0.00219129,-0.038070942999999996,-1.403621809,-1.918238937,-2.285301763,-2.464851468,0.694033511,0.711950767,-9.370869312,-9.577374747999999,-10.22538933,-8.326599075,-7.695923546,-11.02905986,-6.8343540339999995,-4.17936011,-1446.5611975663342 -4208,4208,A245N,-0.020302232,-0.669554619,-1.5085353590000001,-2.305665431,-2.405268093,-0.029796603999999997,-0.02384896,-0.016755503,-0.002361808,-0.39509320299999995,-0.9440160340000001,-1.4858487930000002,-1.531221925,-2.590631896,-2.020698965,-2.686191669,-2.124344517,1.6679073469999999,0.21838492,-10.10502652,-10.42772224,-10.03907861,-9.575649025,-9.721446938,-10.76123576,-9.622734055,-9.907180409,-1452.3309924993664 -4209,4209,A245Q,-0.091997266,-0.901689009,-1.755091111,-2.6301651180000003,-2.8072187619999998,0.005447181,-0.045806056,-0.138188475,-0.014745194,-0.49401850700000005,-1.30935951,-1.749090227,-1.761091994,-2.2896019,-2.970728336,-2.385161674,-3.229275849,1.731964813,0.156113878,-10.65259162,-10.80267835,-10.3892758,-9.821191688999999,-10.4011254,-11.84868687,-9.622734055,-9.907180967999999,-1453.532018048223 -4210,4210,A245P,-0.016626553,-1.62681056,-2.018825647,-2.308049668,-3.0093595239999997,-0.010792111,-0.01534006,-0.017913046000000002,-0.035187772,-1.6539999930000002,-1.599621126,-1.998706941,-2.0389443519999997,-2.208225395,-2.407873941,-2.7809064230000002,-3.237812625,-0.553613789,-1.06572681,-10.07812543,-9.784262878,-10.37555206,-9.396767159,-10.04391891,-10.79012617,-9.622734055,-9.907181415,-1452.4723177608103 -4211,4211,A245S,-0.00017409900000000001,0.006818566999999999,-0.027245197000000002,-0.019631671,-0.090878592,-0.033718448,-0.011889283999999998,0.011541087,0.017490732,-0.002357031,0.015994163999999998,-0.030154687000000003,-0.024335707,-0.009979021999999999,-0.02928432,-0.08091111599999999,-0.10084606800000001,1.3438084190000001,2.373334145,-3.57832469,-3.95941568,-3.8275830539999998,-3.620427284,-2.245999161,-4.238198273,-4.808467641,-3.8787244739999998,-1458.2376520843245 -4212,4212,A245R,-0.009630441,-1.5850774109999999,-2.176317519,-2.223843198,-2.617993368,-0.055968687,-0.008950268,-0.010310614000000001,-0.057285422999999995,-1.7387996159999999,-1.431355205,-2.138554131,-2.214080907,-2.063641851,-2.384044545,-2.501624305,-2.734362431,-0.414915417,-1.090991343,-10.03551169,-9.93696907,-9.839323547000001,-9.070546211,-9.57984903,-11.75087059,-8.600917371,-7.222716349,-1449.238384743221 -4213,4213,A245T,0.01883738,-0.000910474,0.003203478,-0.18326693300000002,-1.716790487,-0.007667064,0.06434682,-0.026672061,0.028130814,-0.014890665,0.013069717,-0.020718875,0.027125831,0.016725632,-0.383259498,-1.5097245609999999,-1.923856412,0.638492736,1.3165494340000001,-7.125350983,-7.052668716,-7.42058194,-7.048399483,-6.4140508579999995,-7.6910539170000005,-7.576814111,-6.320433206000001,-1454.6479612039402 -4214,4214,A245W,0.008167727,-0.127276629,-1.601351016,-1.8003337640000001,-2.025842414,0.043850062,0.065934498,-0.049599045,0.0049109670000000005,-0.031736615,-0.222816643,-1.773913811,-1.42878822,-1.8373042290000001,-1.763363299,-1.9328640030000002,-2.118820824,1.092962418,0.032650623999999996,-11.59341184,-11.56808339,-12.15293452,-10.82190912,-10.56905411,-12.85507806,-9.622734055,-9.907181365,-1440.9975215038285 -4215,4215,A245V,-0.043080262,0.006312356,-0.010974676000000001,-1.119378317,-1.857539899,-0.01964983,-0.02156866,-0.064591863,0.000698814,0.028725379,-0.016100668000000002,-0.00397934,-0.017970011,-0.49706636299999996,-1.741690271,-1.9970321869999998,-1.71804761,1.637455191,1.376704802,-7.380883524,-8.287683456,-8.603614182000001,-6.01974408,-6.131548538,-7.8618273620000005,-6.582933861,-3.0958723160000003,-1455.4648140147328 -4216,4216,A245Y,0.006988666,-0.307583865,-1.7432949080000002,-2.0959627430000003,-2.698135226,-0.013377301999999999,0.035598535,-0.021621203,0.017926763000000002,-0.144636452,-0.470531277,-1.626577723,-1.8600120919999998,-2.070179383,-2.121746103,-2.387587906,-3.008682546,3.279747216,1.584531584,-11.79245325,-12.34916969,-12.65904759,-10.63697308,-10.02999888,-13.28707699,-9.622734055,-9.907181839,-1442.4084412637167 -4217,4217,A246C,-0.038855122,-0.013791643000000001,-0.032680972,-0.033651374,-0.037628876,0.004257053,-0.026815771000000002,-0.050894472999999996,0.02294918,0.040636645,-0.06821993,-0.011661866000000002,-0.053700078,-0.020833962,-0.046468785,-0.006976392,-0.06828136,1.3647520519999998,2.591121225,-7.511261246,-7.4656461489999995,-7.759582602999999,-7.488099564,-7.084003372000001,-7.758974541000001,-8.542404703999999,-6.401769387000001,-1461.889193132054 -4218,4218,A246E,0.027042978999999998,-0.008681236,-0.01446366,-0.637217003,-1.7565584490000001,0.024283676,0.038845352,0.015240605,0.011614873999999999,-0.033132497000000004,0.015770025,-0.053790055,0.024862735,-0.16848054699999998,-1.105953458,-1.798598765,-1.714518133,1.15621781,1.3360150720000001,-7.798163943,-7.294775871000001,-8.26490078,-8.068260445,-7.711608086,-7.651274536,-8.549402723,-6.433542075,-1449.0472134700976 -4219,4219,A246D,-0.026338631,0.003044556,-0.670025332,-1.8528062769999998,-2.60408801,-0.015015526000000001,0.006390761,-0.059068023,-0.041070981,0.018031512,-0.011942399999999999,-0.074032951,-1.266017712,-1.64812323,-2.057489323,-2.298444834,-2.909731185,0.68114755,0.6926753309999999,-8.166625002,-7.620525367999999,-8.423446236,-8.542701225,-7.839656357000001,-8.406795822000001,-8.549402723,-6.433542077,-1445.9782568202354 -4220,4220,A246G,-0.004841436,-0.003428353,0.0035406920000000002,0.001633932,-1.612438124,-0.01713011,-0.01293235,0.0032494790000000004,-0.030809296,0.018118223,-0.024974927999999997,0.030447767,-0.023366384,0.025425526,-0.022157662999999998,-1.280499254,-1.944376993,0.9151945840000001,1.35749758,-7.1517617,-6.9713293610000004,-6.72309465,-7.250945602000001,-7.153478462000001,-7.6599604260000005,-8.521964203,-6.272064761,-1452.6673058220185 -4221,4221,A246F,0.012082878,-0.014821313000000001,0.002246737,0.01790357,-0.031573143,0.001372596,0.013570138999999998,0.010595617,-0.047333824000000004,-0.016652865,-0.012989761,-0.00287935,0.007372824,-0.016472335,0.052279475,-0.06258537,-0.000560916,1.278958819,2.318561243,-3.017167175,-4.045339905,-2.942600014,-3.409385559,-1.573764664,-3.114745735,-3.8982562819999997,1.319550008,-1458.3892781930044 -4222,4222,A246I,0.008971914000000001,-0.028538519,0.011916932,-0.000271221,-0.007062572,-0.046142221,0.021550465,-0.0036066379999999997,-0.012070533999999999,-0.022564355,-0.034512682,0.019317251,0.004516612,-0.031894282999999995,0.031351841,0.000530706,-0.01465585,1.338437336,2.636100114,-1.73596864,-1.815357307,-1.5183206480000002,-1.34332769,-1.8523696669999998,-2.150467888,-2.745419317,3.5197197080000002,-1470.1802876684815 -4223,4223,A246H,-0.027854181000000002,-0.019554966,-0.029184063,-0.995243903,-2.532376938,-0.042546123,-0.007470508000000001,-0.048237853,-0.03877869,-0.05729938,0.018189449,0.011881678,-0.070249804,-0.39803123700000004,-1.592456568,-1.961202665,-3.103551211,1.518855483,1.3619623140000001,-6.3779513979999995,-6.546391517999999,-6.648508835,-6.45850312,-5.706768845,-6.529584671,-6.684925819,-2.979100805,-1451.6381208929233 -4224,4224,A246K,-0.038384532,-0.014214087,0.003907870999999999,-1.440481937,-2.3727348480000003,-0.033192909,-0.061138677999999995,-0.015630385,-0.104960275,-0.024509378999999998,-0.003918795,0.053984575,-0.046168833,-1.197856249,-1.683107625,-2.715270187,-2.030199508,0.794432611,0.7396772979999999,-8.139322398,-8.071451706,-8.502227097,-7.8311148610000005,-8.036897339,-8.25492099,-8.549402723,-6.4335420789999995,-1451.6447309665382 -4225,4225,A246M,0.047774317999999996,-0.012291976999999999,0.019714092,0.018304669,-0.000321423,-0.027254141000000003,0.042561798,0.052986838,0.000903551,-0.004261502,-0.020322451000000002,0.023251293,0.01617689,-0.00874292,0.045352257,-0.008986592,0.008343745999999999,1.27680444,2.487647338,-2.066374289,-2.77452105,-1.853202156,-1.950380653,-2.613277054,-1.140490532,-3.70162098,0.47829554799999996,-1473.5526846838184 -4226,4226,A246L,0.031707584,-0.0008271789999999999,0.016469642,0.010161871999999999,0.050627818,-0.007193934,0.031206861000000002,0.032208306,-0.013609818999999999,-0.000427395,-0.001226963,0.02460412,0.008335163,-0.024648391000000002,0.044972135,0.039115789,0.062139846,1.079231291,2.779376345,-1.397399016,-1.7467251430000001,-1.282364517,-1.517431068,-1.4705755619999998,-0.969898788,-2.879784822,2.257176808,-1473.557030510623 -4227,4227,A246N,0.004754704,0.030959726,0.020177208999999998,-0.10577875800000001,-2.121236944,-0.037931134,-0.005398292,0.014907698999999998,0.005798157,0.103565233,-0.041645781,0.070730533,-0.030376116,0.039342185,-0.25089970100000003,-1.532192807,-2.71028108,0.44791524899999996,1.307913145,-8.047341643,-7.771866692000001,-8.177812416,-7.812602646,-7.7031547929999995,-8.771271667,-8.064182574,-4.532428956,-1452.9802602073178 -4228,4228,A246Q,-0.026453234,-0.011062802,0.00984068,-0.18298975899999997,-1.3833122830000002,-0.021267794,-0.048775905999999994,-0.004130561,-0.050459198,0.019378557,-0.041504161,0.068240937,-0.048559577,-0.044861205,-0.321118313,-1.4041442119999998,-1.362480353,0.702965446,1.3262142670000001,-7.636120428,-7.498932892000001,-7.809017715,-7.318815285,-7.85588945,-7.6979467999999995,-8.549402723,-6.4335420789999995,-1456.58344319975 -4229,4229,A246P,0.026894836000000002,-1.165469766,-1.84631407,-2.177271696,-2.633705164,-0.004090843,0.035144679,0.018644993000000002,-0.010389496,-0.952730851,-1.378208681,-1.867324903,-1.825303237,-2.142468137,-2.212075255,-2.5643104119999998,-2.703099915,3.369627491,1.3067817659999998,-7.814902162,-7.73005352,-8.289153969,-7.849309959,-7.613791565,-7.592201797,-8.549402723,-6.433542077999999,-1448.71712604817 -4230,4230,A246S,0.024594902999999998,-0.012990936000000002,-0.007595135,-0.007267241,-0.25935693600000004,-0.022867084,0.033337423,0.015852381999999998,-0.03315398,-0.022794032000000002,-0.003187839,-0.00061581,-0.01457446,-0.036680393,0.022145912,-0.132649009,-0.386064863,1.293853984,2.16233844,-6.666760973,-6.552632065,-6.04568029,-6.307207161,-6.192758682000001,-8.235526665,-8.549402723,-6.433542077,-1452.9168739048764 -4231,4231,A246R,-0.014371983,-0.018896976,-0.91153526,-1.986564,-2.565881715,-0.029488944,-0.018339031000000002,-0.010404934000000001,-0.017091376999999998,-0.013750861000000001,-0.02404309,-0.389652513,-1.433418006,-1.978311454,-1.994816545,-2.403180184,-2.728583245,1.483306379,0.714785115,-6.652902425,-6.215869789,-6.9298059389999995,-6.33717366,-6.699486778,-7.0821759570000005,-6.5883090289999995,-2.48619131,-1450.5224106535316 -4232,4232,A246T,0.005329401,-0.007641452,-0.022717636,-0.020290119,-0.031454708,-0.002723244,0.001670223,0.008988579,-0.024067087,-0.031038932999999998,0.015756028999999998,-0.01588241,-0.029552862000000003,-0.049581339,0.009001101,-0.03940328,-0.023506136,1.396660159,2.52588199,-4.589915735,-4.5441883469999995,-4.431337479,-4.340063011,-4.435207191,-5.198782646000001,-5.979224138999999,-1.95932159,-1462.4669838403352 -4233,4233,A246W,-0.010950095,-0.011612023,-0.007504243000000001,-0.255592639,-1.7332458780000002,0.058050733,0.001473744,-0.023373933,-0.063525234,0.015244191,-0.038468236,-0.012244113999999999,-0.002764371,-0.061803127,-0.44938215,-1.6140743380000002,-1.8524174180000001,0.8575666129999999,1.324697695,-6.535964009,-6.931611877000001,-7.341641151,-5.85939563,-5.241808075,-7.305363312000001,-6.226937931,-1.63400786,-1455.7369432933629 -4234,4234,A246V,0.004073374,-0.001290251,0.006471136,0.0011163689999999999,-0.0077652419999999995,-0.015179048999999998,-7.159999999999999e-05,0.008218346999999999,-0.012324765,0.004896008,-0.00747651,0.026326036,-0.013383765,-0.016132378,0.018365116,-0.011959583999999999,-0.0035709,1.671448915,3.643209181,-0.329735574,-0.6758471070000001,-0.356700203,0.19301938600000002,-0.517170799,-0.291979149,-1.943826529,3.353556769,-1472.070062117651 -4235,4235,A246Y,0.011777721000000001,-0.041966456,-0.033315704,-0.006574174,-0.043324547000000005,-0.016667044,0.038109062,-0.014553621000000001,-0.041116828,-0.029941182,-0.053991729,-0.060464471,-0.006166937,-0.048859438,0.035711091,-0.055728365999999994,-0.030920727999999998,1.353146455,2.43625927,-5.631475527999999,-5.947253494,-6.038446205,-6.298144043,-3.983272224,-5.8902616729999995,-5.838548092000001,0.41579707,-1450.7485679164529 -4236,4236,L247A,-0.029964273,0.012110365,0.010283386,-0.457632075,-2.228504933,-0.013562013999999999,-0.048564822,-0.011363723000000001,0.023522535,0.014653706,0.009567023000000001,0.005380541,0.015186231000000001,-0.079262033,-0.836002116,-1.615757501,-2.841252364,0.7970522320000001,1.319448964,-3.909182695,-3.6418026119999998,-4.571821503,-2.872160446,-3.819488106,-4.640640808000001,-4.704781987,-0.475673269,-1458.7096589612775 -4237,4237,L247C,-0.014202751999999999,-0.0009237560000000001,0.020087752,0.008728353000000001,-1.4721740019999998,0.005297491,-0.031975476,0.0035699720000000002,0.059406836,0.010142481,-0.011989993000000001,0.011998399,0.028177103999999998,-0.016323913,0.033780618,-1.181100569,-1.7632474340000002,0.7282868379999999,1.342885724,-8.094891953,-7.6694207,-9.255341255,-7.882702431,-7.594463165,-8.072532211,-6.768621735,-4.509640476,-1456.838808579836 -4238,4238,L247E,-0.043397088,-0.259243406,-1.786156976,-1.956403612,-2.477048234,-0.08935356900000001,-0.060677058,-0.026117117000000002,-0.056184059,0.020275037,-0.5387618479999999,-1.306560041,-2.26575391,-1.6627866040000001,-2.25002062,-2.129038914,-2.825057554,3.871444323,2.449355039,-11.06060649,-10.19148691,-12.20202135,-10.73286736,-10.83952029,-11.33713656,-9.155121949,-8.850971648,-1450.4383391151205 -4239,4239,L247D,-0.048530439,-1.6335809780000001,-1.669960766,-2.101646775,-2.845870413,0.034222543,-0.033974074,-0.06308680400000001,-0.049369885,-1.8660058780000002,-1.401156078,-1.371837206,-1.968084326,-2.074851255,-2.128442295,-2.4441935519999998,-3.247547273,-0.38813607,-1.097039864,-11.53604135,-10.78815274,-13.05423653,-11.28852618,-10.80144897,-11.74784235,-9.155121949,-8.850971648,-1448.3725295709446 -4240,4240,L247G,-0.069727836,-0.65892261,-1.9501453340000001,-2.287564063,-2.816725355,0.003824348,-0.07869287900000001,-0.060762792999999996,0.012468232,-0.317410523,-1.000434697,-2.032756866,-1.8675338019999999,-2.165895607,-2.409232518,-2.649181257,-2.984269452,1.005189251,-0.167189514,-8.614614087,-8.708124947,-9.993940224,-7.682692459,-7.120361679,-9.567951126,-6.192105387000001,-3.85984005,-1444.4740113196895 -4241,4241,L247F,-0.097075138,-0.000980091,-0.019594489,-0.577659555,-1.8005683190000001,0.028884324,-0.072418357,-0.12173191800000001,-0.003169463,-0.025593461,0.023633279,-0.06706409,0.027875112999999997,-0.11739236199999999,-1.037926748,-1.830565103,-1.770571535,0.979980075,1.319224157,-4.509706436,-4.618375702,-6.211122528,-4.5062680969999995,-3.579907196,-3.632858658,-4.5193604380000005,-1.1133314570000001,-1470.3598244371824 -4242,4242,L247I,0.046092954000000005,0.09028587699999999,0.027773269,-0.012085928000000001,0.045515109000000005,-0.029093467999999997,0.040396100000000004,0.051789808,0.054221714000000004,0.083458057,0.097113696,0.025004712000000002,0.030541825,0.010950877,-0.035122732000000004,0.072054614,0.018975603,1.006988195,2.82730381,-1.038436964,-1.283041382,-2.257757034,-0.514259315,-0.47469912,-0.6624279710000001,-3.194412114,0.534409669,-1464.5884678764269 -4243,4243,L247H,-0.05424543,-0.49541200799999996,-1.75074287,-2.483458875,-3.004103497,0.062694606,-0.06580892099999999,-0.042681939,0.050504607,-0.133919863,-0.856904153,-1.741498265,-1.759987474,-2.541422328,-2.425495421,-2.609734629,-3.398472364,0.89970387,-0.007239103,-11.56986987,-9.407322784,-13.42249461,-11.55109064,-11.01786635,-12.45057494,-9.155121949,-8.850971648,-1456.8388912184164 -4244,4244,L247K,-0.004992575,-1.264236336,-2.2893785230000003,-2.420034537,-2.091194156,-0.042449803,0.0034313629999999998,-0.013416513,0.025425813999999998,-1.184069213,-1.3444034580000002,-2.070111783,-2.508645263,-2.171065841,-2.6690032319999997,-2.239378142,-1.94301017,0.203603678,-0.7349031540000001,-10.94370031,-10.00024883,-12.54662573,-10.42992614,-10.02161974,-11.72008111,-9.155121949,-8.850971648,-1454.812012642622 -4245,4245,L247M,-0.05038785900000001,0.035729343999999996,-0.07620875,-0.037459542,0.046639438,-0.01368382,-0.006490944,-0.094284774,0.0046119279999999995,0.095794103,-0.024335416000000002,0.019646185,-0.172063684,0.052624749000000005,-0.127543833,0.102880002,-0.009601126,1.130958758,2.8360434089999997,-2.402793707,-2.565386604,-2.479818283,-2.468709793,-2.045446762,-2.454607094,-3.980924785,-2.098778888,-1469.0245096799918 -4246,4246,L247N,-0.086416069,-1.302444277,-1.990281135,-1.750755804,-2.593126764,0.022387656000000002,-0.114006804,-0.058825333,0.08261434,-1.130823701,-1.474064852,-2.016866271,-1.9636959980000002,-2.117820329,-1.3836912780000001,-2.18613263,-3.000120897,3.8173601130000003,1.648728583,-10.81016592,-10.12227948,-11.77259896,-10.76317669,-10.23701371,-11.15576077,-9.155121949,-8.850971648,-1455.4257914209738 -4247,4247,L247Q,-0.057797797000000005,-0.062653949,-1.54141911,-2.634214766,-2.566813759,-0.074259546,-0.07785665900000001,-0.037738935,0.061648382,0.004646267,-0.129954165,-1.316319878,-1.766518341,-2.496455182,-2.77197435,-2.2637374880000003,-2.8698900289999996,0.542034365,0.05795784599999999,-10.54642649,-9.869404686000001,-11.37236807,-10.63517986,-9.517071547999999,-11.33810826,-9.145504072,-8.785018815,-1457.1545355808921 -4248,4248,L247P,-0.060855755,-0.869438465,-1.7533471580000002,-2.00454277,-2.202595062,-0.029615591,-0.061775593,-0.059935917000000005,0.01160054,-0.599701871,-1.139175058,-1.7164869040000001,-1.790207411,-1.957619665,-2.051465875,-2.0928787559999997,-2.312311367,4.261369202,2.445845369,-10.70571882,-10.09790717,-11.57025111,-10.39463721,-10.38361152,-11.08218707,-9.155121949,-8.850971648,-1448.4586663502268 -4249,4249,L247S,-0.0016737229999999998,-0.02605746,-1.234897092,-1.9571133330000001,-3.157485965,-0.040440994,-0.016704232,0.013356786,0.034982656,-0.023147735,-0.028967185,-0.921627621,-1.5481665619999998,-1.946064824,-1.9681618419999998,-2.429350474,-3.8856214560000004,2.200343237,0.94216039,-9.199146411000001,-9.134909332000001,-9.726421593,-8.877574447999999,-8.822039436,-9.434787247000001,-8.40637304,-6.253445107,-1456.4019535402767 -4250,4250,L247R,-0.062931721,-1.528493684,-2.052890538,-1.988923589,-2.478849363,-0.034273154,-0.064490761,-0.06137268,0.011497916,-1.598710848,-1.458276519,-2.419812611,-1.685968464,-2.094797937,-1.88304924,-2.4641402340000003,-2.493558492,-0.587671425,-1.039479026,-11.41004197,-10.68116383,-11.96905318,-11.28383128,-10.659224400000001,-12.45693716,-9.155121949,-8.850971648,-1452.3285530232824 -4251,4251,L247T,-0.041101847999999996,-0.01539265,-0.012122843000000001,-0.022290192,-1.595811523,-0.015417462,-0.063913841,-0.018289855,0.048392522,0.012907749,-0.043693048,-0.018631615,-0.00561407,-0.025523502000000003,-0.019056881,-1.177612801,-2.014010245,0.736709026,1.345276163,-5.652886406,-5.3820952,-6.685633507,-5.081616783,-5.3270155180000005,-5.7880710220000005,-4.711481597,-2.367119789,-1460.3427177481353 -4252,4252,L247W,-0.060791867,-0.081425194,-0.031796054,-0.082409111,-1.617789559,0.012270484,-0.025115709,-0.096468025,0.056476544000000004,-0.051137285,-0.11171310300000001,-0.039053287,-0.024538821000000002,0.013482848,-0.17830106899999998,-1.4098048719999998,-1.825774246,0.60156222,1.319371867,-10.00818463,-9.145144646,-11.9610024,-9.720297096,-9.150637779,-10.06384121,-7.764980506000001,-5.192655301,-1465.8377058226615 -4253,4253,L247V,-0.035773035,-0.024431507999999998,-0.01884707,-0.039030294,-0.031333964,0.005880531,-0.027881087000000002,-0.043664983,0.019649913,-0.034952963,-0.013910053,-0.037154714,-0.000539426,-0.041088406,-0.036972181,-0.057072827,-0.0055951,1.31939238,2.426049301,-1.7905767430000001,-0.617960495,-2.96288414,-1.630470154,-1.774779198,-1.966789726,-2.7825877739999996,1.057655568,-1461.1693626400083 -4254,4254,L247Y,-0.020940984,0.059855236,-0.200521927,-1.486413716,-2.78760903,-0.031000688999999998,-0.0052586759999999995,-0.036623291,0.076829504,0.055886534,0.063823938,-0.08891686900000001,-0.312126985,-1.169349259,-1.803478173,-2.351604913,-3.223613147,1.036241985,0.779264415,-8.228036693,-6.216832405,-11.59725136,-7.837054183999999,-7.731956291,-7.757089226000001,-5.00301725,-3.249191319,-1470.0037337713875 -4255,4255,G248A,-0.020177845,7.55e-05,-0.12603547,-1.5442891909999998,-2.338369499,0.016345092,-0.033751002,-0.006604688,-0.053061644000000005,-0.017471102,0.017622123,-0.051887130999999996,-0.20018380800000002,-1.304717014,-1.7838613680000002,-2.1828260619999997,-2.493912936,0.353470351,0.701986042,-6.154536302,-6.4191538239999995,-4.604703667,-5.499897728,-8.292023308,-5.956902985,-6.069141191,0.135368199,-1462.9335292475298 -4256,4256,G248C,-0.00215753,-0.061574184000000004,-1.319188816,-2.200912921,-2.276509166,0.006703817,-0.016371437,0.012056378000000001,-0.04089358,-0.01225679,-0.110891578,-0.982963053,-1.655414578,-2.194764287,-2.207061555,-2.408880913,-2.144137419,1.948764074,0.697703965,-8.942540142999999,-9.365344406,-8.414338821,-8.495728432,-10.24019026,-8.197098793,-7.109318026,-1.467607963,-1447.9020906761289 -4257,4257,G248E,-0.009770056,-1.0468448190000001,-1.7607896459999999,-2.004282849,-2.0217645,0.05060585,0.006549049,-0.026089161,0.048645137000000005,-0.7948993259999999,-1.298790312,-1.736668996,-1.784910295,-1.998636839,-2.009928859,-1.9372775740000001,-2.106251425,4.299227179,2.408867543,-7.026289512999999,-9.268737885,-5.599913757,-4.952293274,-8.429235756,-6.881266891,-5.778276647,2.1079617109999997,-1461.7004158380441 -4258,4258,G248D,0.004725838,-0.17175427399999998,-1.5045250380000001,-2.035302703,-2.467998155,-0.010500608,-0.031037426,0.040489102,0.017426856,-0.05372280000000001,-0.289785748,-1.282500626,-1.72654945,-1.8832870259999999,-2.187318379,-2.562290451,-2.373705859,2.755090876,1.274723937,-9.407323853,-11.04365467,-8.390716125,-7.369265121000001,-10.28331835,-9.949664992999999,-6.449675096,1.091934785,-1454.0345036112703 -4259,4259,G248F,-0.003476073,-0.36182351700000004,-1.6463530830000002,-2.316307975,-2.9622858689999996,0.015713348999999998,-0.022047168,0.015095023,0.017095171,-0.10029065599999999,-0.623356377,-1.495132831,-1.797573335,-2.706934065,-1.925681885,-2.54083945,-3.383732287,0.814595485,0.045374607000000004,-9.414263814,-8.927387589,-7.505537628,-9.257241264,-11.842495800000002,-9.538656784,-4.602923946000001,1.8298097480000002,-1449.5415851785801 -4260,4260,G248I,0.047318026,-0.931757165,-2.112793349,-2.3857754819999997,-2.2749781159999998,0.040800006,0.058977422,0.03565863,0.004847666,-0.7751119470000001,-1.088402382,-2.098222364,-2.127364334,-2.163895561,-2.6076554030000003,-2.599860938,-1.9500952930000002,0.901266067,-0.516491224,-7.491509612000001,-6.747448906,-5.267815186,-7.436018913,-8.52512384,-9.481141212,-5.105059488,0.23613401899999997,-1445.5911420588382 -4261,4261,G248H,-0.003232725,0.044930621,-0.001345667,-1.660893582,-2.811644134,0.021351475,-0.033199325,0.026733876,-0.00852285,0.035408597,0.054452644,0.025374095,-0.028065429,-0.914940555,-2.406846608,-2.189755022,-3.433533245,1.955867671,1.370507963,-8.339643365,-8.350147491,-6.931704407000001,-7.5951158979999995,-10.61446922,-8.206779816000001,-6.1652006660000005,0.11198201,-1456.406693436671 -4262,4262,G248K,0.00109662,-0.09097734199999999,-1.3487460619999998,-1.9718327340000001,-3.0922343660000005,0.02696065,-0.005795911999999999,0.007989151,-0.04775034400000001,-0.020108731,-0.161845952,-1.071937856,-1.6255542669999998,-2.091853564,-1.8518119030000002,-2.7039101989999996,-3.480558532,2.200772844,0.872783103,-7.792364645,-7.951387512,-6.387075684,-7.2768956220000005,-9.028849007,-8.317615402000001,-6.0504582010000005,0.446226965,-1462.4398919609375 -4263,4263,G248M,0.002086932,-0.484316157,-2.122213996,-2.314234978,-3.118625003,0.010267271,-0.020849737,0.0250236,-0.015496488999999999,-0.178471223,-0.790161091,-2.22075503,-2.023672961,-2.462519487,-2.165950468,-2.5974548680000002,-3.6397951369999997,0.416306975,-0.33691998799999995,-8.864130396,-7.796717041,-6.834719925,-9.844347313,-9.374752578999999,-10.47011512,-5.77731895,-0.528918247,-1455.7035105717368 -4264,4264,G248L,-0.012250522,-1.214422065,-2.081868533,-2.207003723,-3.208285772,0.023227092999999997,-0.035808458,0.011307415,-0.022138335,-0.998764955,-1.430079175,-2.1897329819999998,-1.9740040840000002,-2.1828555130000002,-2.231151933,-2.9546129910000003,-3.461958553,0.629656282,-0.610327155,-8.679496524,-7.212098877000001,-7.014086128,-8.26454306,-9.543995331,-11.36275922,-4.434664553999999,0.8837610370000001,-1447.2949536731467 -4265,4265,G248N,-0.064752308,0.012548907,-0.11777682699999999,-1.892474152,-2.968898199,-0.016044719,-0.0799957,-0.04950891599999999,-0.023088532000000002,0.034147944,-0.00905013,0.050985589000000005,-0.28653924199999997,-1.502028029,-2.282920275,-2.482061449,-3.455734948,0.538745785,0.6958540209999999,-9.146227632,-9.975694366,-8.560578528999999,-8.697232277000001,-9.816987198,-8.68064579,-6.183730493,0.723134443,-1459.8671634155326 -4266,4266,G248Q,-0.058969575,-0.321495676,-1.573450693,-2.189131425,-2.82691411,0.054314188,-0.06559867900000001,-0.052340471,-0.055906349,-0.07597924,-0.567012112,-1.4797455880000001,-1.667155798,-2.08948683,-2.28877602,-2.8264822019999998,-2.827346018,0.902334284,0.055703275999999996,-6.1547509510000005,-6.7251492310000005,-5.223781334,-5.251512665,-7.356614532,-6.216696991,-5.51021716,0.625256546,-1464.569121079985 -4267,4267,G248P,-0.010249036,-1.6722108740000001,-2.048928412,-2.372155148,-3.3193927000000003,0.004158917,-0.029869173,0.009371101,-0.11344488900000001,-1.74130084,-1.6031209080000002,-2.049852537,-2.048004287,-2.188076402,-2.556233893,-2.820336423,-3.818448977,0.054915625999999995,-1.080016205,-10.62480688,-10.61881342,-9.436379898,-9.777303024,-12.72000624,-10.57153182,-8.206136964,-2.44071098,-1455.6846679872833 -4268,4268,G248S,-0.029739677000000003,-0.016820368,-0.05410371,-1.533001036,-2.356738345,0.028331527000000002,-0.041062452,-0.018416902,-0.037630034,-0.008555874,-0.025084861,-0.009830591999999999,-0.09837682699999999,-1.19416312,-1.871838951,-2.373302164,-2.340174525,0.6059375579999999,0.7206050820000001,-6.255957784,-5.608257903999999,-6.309202415,-5.85840493,-8.603635376,-4.900288292,-4.961587066,0.583989336,-1457.7528756028041 -4269,4269,G248R,-0.025318399,-0.019303156999999998,-1.213143885,-1.9939185419999998,-2.4059675080000003,0.015247041999999999,-0.048178433,-0.0024583639999999998,-0.040672639,0.023404957999999997,-0.06201127099999999,-0.887325633,-1.5389621359999999,-1.8306842380000001,-2.157152845,-2.103922317,-2.708012698,3.546397689,2.23131895,-5.249103955,-4.862978706,-4.418665466,-4.491831008999999,-7.355614417999999,-5.116430176000001,-4.600007878,1.282242025,-1462.534446542617 -4270,4270,G248T,-0.006037865999999999,-0.470562315,-1.9652026219999998,-2.106564038,-3.06367362,0.04443157,-0.004611275,-0.007464457,-0.003186622,-0.15020472599999998,-0.7909199029999999,-2.111804399,-1.818600845,-2.126325075,-2.086803001,-2.9144729689999997,-3.2128742710000004,0.581349527,-0.22706669899999998,-5.679486687000001,-5.52503508,-3.9178027269999998,-5.460523705,-8.758514862,-4.73555706,-4.396135467,2.276019147,-1461.6848115492612 -4271,4271,G248W,-0.046069287,-0.035351886,-1.163058568,-2.187765798,-2.5157898640000003,0.021786253,-0.059384295,-0.032754278,-0.03269935,0.010082648,-0.080786419,-0.84814097,-1.477976165,-1.940143107,-2.435388489,-2.580228466,-2.451351261,2.084947253,0.895574998,-6.358588025,-6.466692329,-7.02859671,-5.171717918,-9.771783997,-3.35414917,-3.2209097989999997,3.15904239,-1456.9897688003257 -4272,4272,G248V,-0.03305388,-1.000011231,-2.010858701,-2.1749302040000003,-2.830067718,0.008257405,-0.051169183,-0.014938576,0.016773695,-0.716668214,-1.2833542470000001,-2.053618614,-1.968098787,-2.1192918119999997,-2.230568595,-3.1292884560000003,-2.53084698,1.1549109359999998,-0.34254151899999996,-7.955326802,-7.48012603,-5.503853027000001,-7.3649894179999995,-10.20109015,-9.226575386,-5.722703479,0.14531326,-1450.7581403702497 -4273,4273,G248Y,-0.010458871,-0.245343247,-1.530777927,-2.418984521,-2.8404161489999997,0.036971647999999996,-0.013147918,-0.007769823,-0.040195387,-0.020542809,-0.470143684,-1.431608396,-1.6299474569999999,-2.0413496380000002,-2.7966194030000002,-2.079375006,-3.6014572910000004,3.9388463369999998,2.361626136,-8.750681474,-9.60867231,-6.731304778999999,-8.644083611000001,-10.9171835,-7.85216317,-3.335030562,2.147633682,-1451.1041888487525 -4274,4274,P249A,0.027463187000000003,0.018360498,-0.009839366,-0.001992438,-0.5783242510000001,-0.040891367000000005,0.014584032,0.040342342,0.016375635,0.01057239,0.026148605,-0.016629022,-0.0030497090000000003,-0.013484262,0.009499387,-0.298469166,-0.858179336,1.353395209,1.912290501,-3.640234224,-3.521347122,-3.187146568,-3.52513549,-3.6329701919999997,-4.334571747,-4.398757885,-1.442033785,-1463.8883751155809 -4275,4275,P249C,-0.018637671,-0.007107166999999999,-0.032167984,0.02083007,-1.200239393,0.001129808,-0.020940726,-0.016334615,0.040035404,-0.044096707,0.029882374,-0.05251465599999999,-0.011821311000000001,-0.014901174,0.056561314,-1.118172977,-1.2823058090000001,0.848274813,1.364160944,-8.763224187,-8.203470047,-9.524136283999999,-8.042903946000001,-8.417202652,-9.628408005,-7.888805541,-4.820274008999999,-1456.70259401761 -4276,4276,P249E,-0.052040973,0.016823026,-0.026175775,-0.018463989,-0.668956032,0.089514434,0.014668513000000001,-0.118750459,-0.08375613900000001,-0.021133059,0.054779111,-0.041442098,-0.010909452,-0.08200175700000001,0.04507378,-0.453559765,-0.884352299,1.537695302,1.908538703,-6.841610875,-6.719674065,-7.006441841,-5.979129692000001,-6.703627357,-7.799181419,-7.323274277,-4.74577004,-1461.9373618764803 -4277,4277,P249D,-0.08128052599999999,-0.004573971,-0.031232138,0.023382083999999997,-1.041499991,0.0019526110000000001,-0.006702164,-0.155858887,-0.030489705,-0.012988342,0.003840401,-0.024677587999999997,-0.037786688,-0.001699355,0.048463522,-0.631867109,-1.4511328730000002,0.588675896,1.383666835,-5.916577115,-6.411473846,-5.703488342000001,-5.516362419,-5.878126915,-6.0734340520000005,-6.325639288,-3.8279198969999997,-1460.2744895946234 -4278,4278,P249G,-0.025055623,-0.01026121,0.006090111,-0.502201031,-1.611388635,0.015462711,-0.027995316,-0.02211593,0.008017338,0.001660784,-0.022183203999999998,-0.019979331,0.032159553,-0.090174097,-0.9142279640000001,-1.6040322969999998,-1.618744973,0.891579346,1.330430316,-5.4691526470000005,-5.5425874020000006,-4.754764755,-5.218153435,-5.394146912,-6.436110733,-5.171776482,-2.114497329,-1456.976401489228 -4279,4279,P249F,-0.121307136,-0.035532408,-0.074673739,-0.7427068259999999,-2.2553291619999998,-0.011996355,-0.11373303400000001,-0.128881238,-0.02676797,-0.019737361000000002,-0.051327454,-0.034136396,-0.11521108099999999,-0.139787633,-1.345626019,-1.9623440280000002,-2.548314295,1.031408188,1.312043906,-9.88598922,-8.112584335,-11.98961287,-8.274796227000001,-9.547914917,-11.50503775,-7.348648676,-2.76525778,-1453.3854803335853 -4280,4280,P249I,-0.066508207,0.020159114,-0.019073853999999998,-0.00871615,-1.8087900209999999,-0.007242304000000001,-0.01368472,-0.119331694,-0.070735332,0.055606207000000005,-0.01528798,0.005904561,-0.044052269000000005,0.003425446,-0.020857746,-1.549376663,-2.068203378,0.550480827,1.311128903,-8.599729611,-7.877147712999999,-10.51220399,-6.997642592999999,-8.336400856000001,-9.275252899,-7.07764273,-3.366366943,-1460.718889389187 -4281,4281,P249H,-0.011353552,0.001005746,0.005013401,-0.02053346,-1.15544864,-0.033206857,0.02855796,-0.051265064000000006,-0.010706568999999999,-0.005245001,0.007256492,-0.008658556999999999,0.018685358,-0.013801321,-0.027265598,-0.772215724,-1.538681556,0.5913726460000001,1.3656514709999998,-7.010845582999999,-7.110202537999999,-7.872221328999999,-5.8259726789999995,-6.868502296,-7.377329071,-6.71245531,-2.309731186,-1461.2105051474646 -4282,4282,P249K,-0.134751354,-0.014551571999999999,0.016346997,0.036101923,-0.073359069,-0.017275449,-0.043922322,-0.225580385,-0.025569388999999998,0.0070558159999999995,-0.036158959,0.043782627000000005,-0.011088633,0.059231362999999995,0.012972481999999999,0.064276775,-0.21099491199999998,1.109854876,2.9255198019999997,-5.924984605,-6.76766021,-6.354243256,-4.666414734,-5.688364967,-6.148239861,-6.2552095439999995,-3.582647438,-1462.9148974856362 -4283,4283,P249M,-0.028820572000000003,-0.0011662060000000001,-0.033574828,0.006654939,-0.703567053,0.051505819,0.008838243,-0.066479386,0.048516501,0.024127421,-0.026459833,-0.030609044,-0.036540611,0.017160375,-0.003850497,-0.3246274,-1.082506706,1.4810637430000002,1.9712603969999998,-8.64603517,-7.877293823,-10.49444165,-7.813503798999999,-8.217487984,-8.827448593,-7.33628834,-2.562113283,-1462.2813341119327 -4284,4284,P249L,0.002286881,-0.00450836,0.007697221,-0.019641353,-1.682206154,-0.010473551,0.0086805,-0.004106739,0.005328446999999999,-0.016382312,0.007365593,0.008445275,0.006949166999999999,0.008294585,-0.047577290999999994,-1.434248304,-1.930164004,0.590954057,1.317453745,-6.819934868,-5.786453125,-9.44943103,-6.202299728,-6.238078194,-6.423412262,-6.64894929,-0.572270815,-1457.1636611386202 -4285,4285,P249N,-0.070778995,0.084193028,0.007902225,-0.003152983,-0.450898064,0.07924944099999999,-0.020784653,-0.120773337,-0.06731727,0.07862057,0.08976548599999999,-0.035063386,0.050867836,-0.034215786,0.02790982,-0.251435106,-0.650361022,1.6494694669999999,2.212074529,-5.911778421,-6.719954491,-5.962324936,-5.390713524,-5.300014824,-6.1858843310000005,-5.822224351,-3.3715376839999998,-1461.5651280097663 -4286,4286,P249Q,-0.057459305999999995,0.009884568,0.019006563,-0.041142532,-0.292078371,-0.037630558,-0.037367095,-0.077551517,0.003048957,0.033240399,-0.013471263999999998,0.014359058999999999,0.023654067,-0.011596182,-0.070688881,-0.083055104,-0.501101637,1.530051592,2.527548925,-6.436507552,-6.8101110689999995,-7.2399050979999995,-5.321924835,-6.393886017000001,-6.416710739,-6.321260862000001,-4.110613224,-1464.8766383905895 -4287,4287,P249S,-0.018875764,-0.000343416,-0.0325316,0.021475462999999997,-0.658121898,-0.001453281,-0.037468645,-0.00028288200000000003,0.002959615,0.028941658,-0.02962849,0.0033121509999999997,-0.068375351,0.050335828,-0.007384902,-0.334281628,-0.981962167,1.4625719209999999,1.9867951169999998,-3.423505547,-3.226883018,-3.5725658719999998,-3.2898855589999996,-3.878697212,-3.149496071,-5.057118043,-1.9872283480000001,-1458.7269322639331 -4288,4288,P249R,0.001171349,0.02185184,-0.010215739,-0.000622254,-0.132884736,0.013331525,-0.0007789769999999999,0.003121674,0.040207357,0.02919626,0.014507418999999999,0.004762312,-0.025193788999999998,-0.000618172,-0.000626336,-0.05502056,-0.210748911,1.3296244590000001,2.548542363,-5.0715439380000005,-4.631601348999999,-6.766330246,-4.098231064,-5.247879601,-4.613677429,-4.777417654,-2.5315596869999997,-1462.9156398945488 -4289,4289,P249T,-0.019143774,0.037485064,0.003564467,0.002096796,-0.890274021,0.025965723,-0.013009418,-0.02527813,0.009150563,0.060638644000000005,0.014331483,0.038105494,-0.030976561,0.005108385,-0.000914793,-0.48937873299999995,-1.291169309,0.7355418109999999,1.456197072,-3.722260025,-4.231165787,-3.5937457960000003,-3.060887047,-4.142802742,-3.5826987530000003,-4.935841054,-1.427950109,-1460.4670688817278 -4290,4290,P249W,-0.008029177,-0.026755557000000003,-0.002592061,-1.089430358,-2.5984718940000002,-0.028480413,0.012012223999999998,-0.028070578,0.034429982000000005,-0.010061453,-0.043449660999999994,-0.030627777000000002,0.025443656000000002,-0.5055619929999999,-1.673298723,-2.402014038,-2.7949297489999996,1.447972918,1.2415384390000002,-9.832979605,-8.534593994,-11.72788525,-8.918576172,-10.34306238,-9.640780227999999,-7.190239254,-4.281599382,-1450.487592538353 -4291,4291,P249V,-0.005313748,-0.021505232000000003,-0.013830489,-0.002349045,-1.3480607409999998,-0.032854463,-0.009814656,-0.00081284,-0.000725701,-0.024327678999999998,-0.018682783999999997,-0.033692191,0.0060312130000000005,0.00556039,-0.010258479000000001,-1.184433628,-1.5116878530000002,0.8362853490000001,1.355854429,-6.779513597,-6.013790375,-8.38602243,-5.721291892999999,-6.619355682,-7.157107605,-6.185071484,-2.7509979469999997,-1463.7364609437063 -4292,4292,P249Y,0.010223564000000001,0.042372485999999994,-0.003694421,-0.351560821,-1.7162852180000001,0.018419991,0.087665351,-0.06721822400000001,0.02678229,0.01095086,0.073794112,-0.013439575,0.006050733000000001,-0.115991786,-0.587129855,-1.539066517,-1.8935039180000002,1.044873951,1.348934099,-9.792381857,-9.198796394,-12.15349696,-7.8002230379999995,-9.350214218,-10.45917867,-6.861348336,-1.9062949409999999,-1453.506630197633 -4293,4293,D250A,-0.034311400000000006,-0.056401672,-0.040072522,-0.045835838,0.018321109,-0.006250416999999999,-0.028305554,-0.040317245,-0.030596206,-0.076374213,-0.03642913,-0.080707907,0.000562864,-0.047468311,-0.044203365,0.004781946,0.031860272,1.228595653,2.552268184,-2.2588561780000003,-2.101019646,-2.4915460130000002,-2.8817450410000003,-2.150501579,-1.669468613,-2.495889857,0.23284168100000002,-1458.997302587144 -4294,4294,D250C,-0.046761057,-0.055349554,-0.100722086,-0.057974665,0.002043014,-0.035098594,-0.044452755999999996,-0.049069358,-0.038910045,-0.051152522,-0.059546586,-0.062710683,-0.13873348800000002,-0.036107089,-0.07984224,0.028185678999999998,-0.024099652000000003,1.140851641,2.701421792,-7.200121104,-7.309413925,-7.550586182000001,-7.374590607000001,-7.196072403,-6.569942406,-7.709528849,-7.373319994,-1454.1769929816946 -4295,4295,D250E,-0.053075005999999994,-0.055272993,-0.080058388,-0.052378938,-0.040105619,-0.016392834,-0.040161527,-0.065988485,0.006548986999999999,-0.082088534,-0.028457451,-0.13712169800000001,-0.022995077000000003,-0.024191754,-0.08056612099999999,0.007461276,-0.08767251300000001,1.258682364,2.591044681,-0.997211057,-1.201031754,-0.805085663,-1.3681439819999999,-1.135382149,-0.47641173600000003,-2.666249654,0.162554283,-1461.0531672248617 -4296,4296,D250G,-0.035801638,-0.053691910999999995,-0.052782130999999996,-0.059139107999999996,-0.01997566,-0.014804711000000002,-0.041515416,-0.03008786,-0.012805356,-0.078792552,-0.02859127,-0.102018791,-0.00354547,-0.070084187,-0.048194029000000006,-0.024559005,-0.015392313999999999,1.543610422,3.106887046,-2.411519276,-1.7443245319999998,-3.139050262,-2.9849700930000003,-2.325815887,-1.863435608,-2.3048281569999998,-0.335101319,-1454.3881771699525 -4297,4297,D250F,-0.030430468,-0.056233375999999995,-0.036455503,-0.062189592,0.00293398,-0.072130489,-0.026584695,-0.034276241,-0.056147805999999995,-0.07937825,-0.033088502,-0.064401094,-0.008509911,-0.03718057,-0.08719861300000001,-0.013438855,0.019306814,1.186638969,2.423267269,-6.130720723,-6.38076899,-6.464759575,-6.104689919,-5.954971481,-5.748413651,-6.634354269,-4.487608928,-1443.3062705146149 -4298,4298,D250I,-0.04399044,-0.093715849,-0.036430528999999996,-0.086022363,-0.144254011,-0.064806034,-0.055075545,-0.032905335,-0.073155617,-0.102504675,-0.084927023,-0.083249875,0.010388818000000001,-0.062241495,-0.109803231,-0.11937089,-0.16913713100000002,1.396988942,2.265181592,-5.873930118,-5.938421783,-6.307766602,-5.9500929110000005,-5.9743108220000005,-5.199058472,-5.419596599999999,-3.6867524360000004,-1446.7844259822741 -4299,4299,D250H,-0.043928928,-0.047977226,-0.059884152,-0.04110273,-0.008857985,-0.012362725,-0.041156733,-0.046701122000000005,0.019993328,-0.103251839,0.007297388,-0.087065078,-0.032703225,-0.046636421,-0.035569038,-0.049668914,0.031952944,1.3560064680000001,2.430711902,-3.869732083,-4.0129155039999995,-3.81170166,-4.063011505,-4.044136673,-3.416895073,-4.741006504,-2.251801038,-1457.685552236624 -4300,4300,D250K,-0.095810235,-0.11364980699999999,-0.100958588,-0.14032686800000002,-0.064669503,-0.034820627,-0.123669993,-0.067950476,-0.060054723,-0.194275048,-0.033024566,-0.104793845,-0.09712333,-0.09466486699999999,-0.18598886899999997,-0.000765407,-0.128573598,1.412929624,2.559652055,-1.554830315,-2.1369685819999997,-2.019162819,-1.721846512,-0.971579193,-0.924594467,-2.346451509,0.143344869,-1459.2351453006268 -4301,4301,D250M,-0.038329995,-0.09813788300000001,-0.053397892999999995,-0.065352192,-0.003194611,-0.020398395,-0.029460264,-0.047199726,-0.074607795,-0.09332350699999999,-0.102952258,-0.055534945999999995,-0.05126084,-0.056578924,-0.074125459,0.020153261999999998,-0.026542483999999998,1.076833718,2.62284945,-5.959386055,-5.325632973,-6.393387947000001,-6.637708542,-5.74915921,-5.6910416029999995,-5.443172873,-3.5922466060000002,-1450.991750143934 -4302,4302,D250L,-0.020903816000000002,-0.058963735999999996,-0.057688328,-0.072366492,-0.036004745,-0.034402029,-0.02540605,-0.016401581000000002,-0.013702978000000001,-0.105613377,-0.012314094,-0.104887132,-0.010489523,-0.070130152,-0.07460283200000001,-0.049979160999999994,-0.022030328999999998,1.259084239,2.364667216,-4.979605833,-4.731705032,-5.096466400000001,-5.950430602999999,-4.724300223999999,-4.395126907,-4.476080855,-2.459712917,-1443.8019411400892 -4303,4303,D250N,-0.049927976,-0.083286,-0.044760057,-0.062807818,0.052589912,-0.054596294000000004,-0.061133427000000004,-0.038722525,0.006235116,-0.085180934,-0.081391065,-0.087821031,-0.0016990820000000002,-0.056347216,-0.06926842,0.048826363,0.056353460999999994,1.320658561,2.821707424,-2.3017509919999997,-2.549996925,-2.511057091,-1.920041374,-2.30113102,-2.226528549,-2.991975188,-1.109003476,-1461.3344390997663 -4304,4304,D250Q,-0.035824378999999996,-0.089563318,-0.047413536,-0.046942938,0.040564806,-0.054382627,-0.057979822,-0.013668936000000001,-0.129113894,-0.104784688,-0.074341947,-0.09558789300000001,0.000760822,-0.065266193,-0.028619682,0.004420312,0.07670930000000001,1.27782736,2.666259648,-3.513322182,-3.30660878,-3.788338638,-4.176928139,-3.585806976,-2.708928375,-3.960110887,-0.8835785190000001,-1463.0364251937717 -4305,4305,D250P,-0.02270569,-0.08359243200000001,-0.068639353,-0.061241505,-0.440746278,-0.00737404,-0.00010174299999999999,-0.045309637,-0.039762905,-0.103838301,-0.063346562,-0.080796998,-0.056481708,-0.050645237,-0.07183777200000001,-0.233316976,-0.648175579,1.4293193130000001,2.053585997,-1.7311053730000001,-0.114875885,-1.185726288,-4.120892754,-2.236009415,-0.9980225220000001,-2.230483065,2.637484111,-1451.4428437263705 -4306,4306,D250S,0.008853191,-0.043927192999999996,-0.04027554,-0.024828407,0.024758952999999997,-0.041445044,0.014548573,0.003157809,-0.05077589,-0.08951853900000001,0.001664154,-0.104771805,0.024220725,-0.038869789,-0.010787024,0.006534995,0.042982911,1.270488892,2.533330658,-2.582229079,-2.650827744,-2.349997009,-2.7590873030000003,-3.32093,-1.830303337,-3.2537595319999997,-0.623608091,-1457.5938029964454 -4307,4307,D250R,-0.015164748,-0.03008887,-0.036792443,-0.04641496,0.024388551,0.002411685,-0.024712458,-0.005617036999999999,-0.017739086,-0.06966974299999999,0.009492003,-0.085302153,0.011717267,-0.051472339000000006,-0.041357581000000004,-0.00838789,0.057164991,1.367983386,2.598846434,-3.6985957860000003,-4.152090775,-3.6606879039999995,-4.454886467,-3.768724358,-2.456589424,-3.630464412,-1.03244067,-1455.692655174993 -4308,4308,D250T,-0.029527937,-0.058690775,-0.035571633,-0.062475662,-0.051200364000000005,0.013103855,-0.041828111,-0.017227763,-0.040009707,-0.10726846400000001,-0.010113085,-0.082266195,0.011122928999999998,-0.089185316,-0.035766007999999995,-0.028519137000000003,-0.073881591,1.2166231140000001,2.35890501,-2.636740903,-2.550002594,-3.203403137,-2.831852928,-2.603488106,-1.994957748,-3.1020382389999996,-0.721311226,-1457.024092801381 -4309,4309,D250W,-0.026401358,-0.06099029,-0.075976582,-0.077202904,-0.04440584,-0.078541343,-0.040920547,-0.011882169,-0.067649198,-0.094923735,-0.027056844,-0.13170417,-0.020248993,-0.068802606,-0.08560320199999999,-0.037807439,-0.051004241,1.323961605,2.40757037,-7.291233484,-7.460956413,-7.231095207,-7.764191444,-7.132293762000001,-6.867630592,-7.709528849,-7.373319994,-1446.2100131432526 -4310,4310,D250V,-0.015911789,-0.032001896,-0.028484045,-0.017952408,-0.065919361,-0.043230027000000004,-0.014436939,-0.017386638,-0.054077944,-0.054151780999999996,-0.00985201,-0.067174119,0.01020603,-0.004999677,-0.030905138999999998,-0.045879215,-0.08595950699999999,1.282303215,2.399132985,-4.452135561,-4.236476799,-5.03330896,-4.692470169,-4.531948303,-3.7664735719999998,-4.316704121,-2.130332556,-1452.1849157433026 -4311,4311,D250Y,-0.045159649,-0.06488633099999999,-0.088249186,-0.050873627000000005,-0.045429450999999996,-0.004258543,-0.012424768999999999,-0.077894528,0.04466585,-0.09181151300000001,-0.037961149,-0.09854489599999999,-0.077953476,-0.091981992,-0.009765262,-0.044595322,-0.04626358,1.3634295769999998,2.39221161,-5.599197983,-6.083595322000001,-5.67045137,-5.221831078,-5.709211487,-5.310900658,-5.351538542,-4.395535105,-1447.2689266558737 -4312,4312,G251A,-0.019234852,0.003103572,-0.0029835720000000003,-0.00410856,-0.06441906,0.000396871,-0.033724718,-0.004744985,-0.0032196409999999996,0.005975378000000001,0.00023176599999999998,0.026616266,-0.032583409,-0.002673687,-0.005543433,-0.047772782,-0.081065337,1.325552123,2.394828569,-2.538602922,-3.316718178,-2.1711925130000003,-1.413539871,-3.356177628,-2.435386421,-4.0974474999999995,-1.501870431,-1451.9956926493905 -4313,4313,G251C,0.01353473,-0.002471768,-0.013907428000000001,-0.039658242,-0.462420625,-0.078066599,0.025774156,0.001295303,0.026346893,0.019174262,-0.024117798,-0.004997194,-0.022817662000000002,-0.012441082,-0.066875401,-0.22032860199999998,-0.704512648,1.4214866780000002,2.1103286619999997,-6.692753555,-7.1063160860000005,-7.138986557000001,-5.83233989,-7.039526688,-6.346598557,-7.649084211,-4.927063355,-1445.4740924062207 -4314,4314,G251E,-0.121813674,-0.004683363,-0.068405993,-0.041845212,-0.086343213,0.006829671,-0.098050353,-0.14557699400000002,0.033839921,0.108432399,-0.117799124,0.030235182000000003,-0.167047167,0.076879796,-0.16057022,0.010370705,-0.183057131,1.318668048,2.949930464,-2.163243079,-2.90920723,-2.026477455,-1.164674553,-2.51436274,-2.201493416,-3.932642665,-1.42032058,-1448.4471346596256 -4315,4315,G251D,-0.08724859900000001,-0.018709866999999998,-0.028835936,-0.036620185,-0.083212315,0.047037409,-0.086332122,-0.088165076,-0.005342829,0.022112777000000004,-0.059532510999999996,-0.01004389,-0.047627982,-0.006384882,-0.066855487,-0.044178484000000004,-0.122246145,1.2672870109999999,2.4455499990000003,-2.23468378,-3.018454727,-1.6713876269999999,-1.257369331,-2.804944008,-2.421263206,-3.264829464,0.348731711,-1452.0542786088772 -4316,4316,G251F,-0.009961013000000001,0.038854633,-0.08159229400000001,0.012606683999999998,-0.36401895,-0.003059031,-0.033889672999999995,0.013967647,0.010837649,0.034518812,0.043190454,-0.044151425999999994,-0.119033162,-0.016512144,0.041725512,-0.235960883,-0.492077017,1.390903398,2.0469748819999998,-7.387342218,-7.010693412999999,-8.824362198,-6.647225601000001,-7.58615554,-6.868274337999999,-7.759209956,-5.077593166000001,-1444.3240943085402 -4317,4317,G251I,-0.008367595,0.047990435,0.005569009000000001,0.005130771,-1.282882225,0.00238011,-0.027761927999999998,0.011026738999999999,0.03025069,0.064485355,0.031495514,0.071406627,-0.060268609,-0.036850719,0.047112260999999996,-0.5867844329999999,-1.978980016,0.935186815,1.496450525,-7.182386806,-7.401642798999999,-8.199230522,-5.992268494,-7.523895676,-6.794896538,-8.115556632999999,-5.625162735,-1442.2557492433116 -4318,4318,G251H,-0.049572215999999995,0.0073088580000000005,-0.063748776,0.008159742,-0.07890309400000001,0.006517490999999999,-0.079185559,-0.019958873000000002,-0.030334067000000003,0.0061915419999999995,0.008426173,-0.005831025,-0.121666526,0.019969745,-0.0036502609999999997,-0.039841724,-0.117964464,1.192226489,2.404097592,-3.869022186,-4.491677719,-4.26505883,-3.320923943,-4.098956749,-3.16849369,-3.953649888,-1.702497528,-1448.3447380610742 -4319,4319,G251K,0.047224199999999994,0.12057648800000001,0.030751837999999997,0.091126554,0.085538885,-0.09537708199999999,0.037755677,0.056692722,0.0045887,0.197122081,0.044030895,0.043114615,0.01838906,0.127780917,0.054472190999999996,0.030022623999999998,0.141055145,1.215730156,2.850969187,-2.511589021,-3.02040847,-2.835493446,-2.1333002619999997,-2.522695129,-2.046047798,-3.5258635760000003,-1.243172285,-1448.7566844229586 -4320,4320,G251M,0.022353993,0.097226344,0.09824291800000001,0.018273782,0.008838474,-0.03178757,-0.021560376000000003,0.066268361,0.074631652,0.004899665,0.18955302300000001,0.052015568,0.144470268,0.011468988000000001,0.025078575,-0.033029122,0.050706069000000006,1.232195707,2.4882579280000003,-7.652187949,-8.070173019,-8.9757407,-6.591430511,-7.923417809,-6.700177704,-8.611842622000001,-6.49544252,-1447.9268217743374 -4321,4321,G251L,-0.06416598,-0.022257133999999998,-0.006624024,-0.01349598,-0.19331511899999998,0.001130294,-0.07295287,-0.05537909,-0.012356543999999999,0.023954773999999998,-0.06846904200000001,0.034874203,-0.048122251,0.010958986,-0.037950946,-0.10254363699999999,-0.2840866,1.3641896409999998,2.335292185,-6.655771392999999,-6.959609672999999,-8.30505619,-5.388981193999999,-6.802414612000001,-5.822795296000001,-6.9825797220000005,-4.926629617,-1441.440823980607 -4322,4322,G251N,0.004120294,-0.006098065,0.011532243000000001,-0.041052975,-0.08669194,-0.048788584,0.00564745,0.002593137,-0.08825393599999999,-0.014380384,0.002184255,0.074152439,-0.051087954000000005,-0.035299666,-0.046806284000000004,-0.038108647,-0.135275232,1.443911584,2.5943434180000002,-2.429296396,-3.190290909,-2.6994366989999996,-1.985289871,-1.772748161,-2.498716339,-3.568728107,-0.22108968199999998,-1454.070513797924 -4323,4323,G251Q,-0.002671093,-0.03194097,-0.029632515,-0.033220992000000005,-0.058285538,-0.035206741,-0.022279764,0.016937578000000002,0.069681198,0.024710522000000002,-0.088592461,-0.026835107,-0.032429923,-0.050566422,-0.015875562,-0.075548382,-0.041022694,1.491438144,2.518791003,-2.542327025,-3.420798645,-3.013189301,-1.6655121380000002,-2.426090904,-2.186044136,-3.8824726939999996,-1.8083557630000002,-1449.2719084741548 -4324,4324,G251P,-0.020497067,-0.008055659,-0.037718312999999996,-0.019530329,-0.608712558,-0.016795271,-0.032068875,-0.008925259,-0.0008516089999999999,0.014636895,-0.030748212999999996,0.0075471309999999995,-0.08298375599999999,-0.0034018890000000004,-0.035658768,-0.293127036,-0.92429808,1.498034246,2.0529496419999997,-4.084390462,-5.018932632,-4.858112,-3.064411942,-5.0637789689999995,-2.416716766,-4.513094894,-3.0628773760000003,-1437.697260923218 -4325,4325,G251S,-0.06350524,0.001434205,-0.023076917000000002,-0.033503494,-0.065623646,-0.0021181760000000003,-0.06695010000000001,-0.060060379000000004,0.011365346,0.046157677,-0.043289268,0.026316666000000002,-0.07247050000000001,0.029465744,-0.09647273099999999,-0.014155504,-0.11709178699999999,1.169552822,2.52275185,-2.865686665,-3.3505922389999996,-2.986963921,-1.9370643230000002,-3.365802307,-2.688010536,-3.487509062,-1.097718043,-1449.7235602955334 -4326,4326,G251R,-0.002208394,0.0036009059999999996,0.006220392,-0.021013165,-0.056149079000000005,-0.026139448,-0.006939086,0.002522298,0.017270808999999998,0.020344763000000002,-0.013142952,0.028768064,-0.01632728,-0.001884425,-0.040141905,-0.029064659,-0.083233499,1.1811270440000001,2.4637254580000003,-4.146481209,-5.351184555,-4.634647514,-3.175568527,-4.627047325,-2.9439581219999997,-5.408371067000001,-2.126816248,-1448.4255814179778 -4327,4327,G251T,-0.01194882,-0.026391987000000002,-0.038451097000000004,-0.023488552000000003,-0.214043801,-0.05659572400000001,-0.016771423,-0.007126217,0.02670127,-0.031682293,-0.02110168,-0.0006612489999999999,-0.076240945,0.011277105,-0.058254207999999995,-0.123457007,-0.304630595,1.360970451,2.2805769259999997,-3.5443283539999997,-4.1140202939999995,-4.012932922,-2.751586357,-3.607063171,-3.2360390239999997,-4.966095978,-1.983958631,-1444.3411692390218 -4328,4328,G251W,-0.078074531,-0.028646297999999997,-0.046584939000000006,-0.032309998,-0.899293474,-0.014130346,-0.075245427,-0.080903634,-0.035382045,0.009849495,-0.067142091,-0.001120505,-0.09204937199999999,-0.013268751,-0.051351244000000004,-0.575320908,-1.223266039,0.8051561290000001,1.449951859,-7.169713205,-7.278478889,-8.54142205,-6.292318099999999,-7.42912513,-6.307221855,-7.879695301,-5.297417607,-1449.214057218749 -4329,4329,G251V,-0.062207818,0.00608112,-0.019932421000000002,-0.008840862,-0.8962735140000001,-0.05705845,-0.069197275,-0.05521836,0.010306275,0.042694362,-0.030532122999999998,0.036777771,-0.076642613,0.038065784,-0.055747507,-0.538965154,-1.253581874,0.60238637,1.406347819,-5.451162943,-6.0612441939999995,-6.135545471,-4.29610775,-5.8805138470000005,-4.88240345,-6.7492255860000006,-3.8998776910000004,-1442.275855822023 -4330,4330,G251Y,0.059122007000000004,-0.016266408,-0.023295325,-0.024735992999999998,-0.181934202,0.035754201,0.084197245,0.034046768,-0.034081435,-0.088482105,0.05594929,-0.025503386,-0.021087263999999998,-0.08540111,0.035929124,-0.182040717,-0.181827687,1.4583066359999999,2.15946925,-6.648239113,-6.484736786,-7.739146469,-6.16349472,-6.951373337000001,-5.9024442520000004,-7.146648611,-3.453854573,-1443.0436394582503 -4331,4331,K252A,-0.063298778,-0.048230377000000005,-0.032751352000000004,-0.031522141000000004,-0.016785141,-0.009214043,-0.07122915099999999,-0.055368404,-0.007681429,-0.004421418,-0.092039336,0.002008809,-0.067511513,0.019317973999999998,-0.082362256,-0.028756043,-0.004814238,1.0988536770000001,2.35255746,-2.944894249,-2.2512293469999998,-2.957151474,-3.2026588360000003,-3.141654511,-3.171777077,-4.032847647,-0.345653435,-1459.428438683506 -4332,4332,K252C,-0.075002662,-0.07209631400000001,-0.068099874,-0.08381664900000001,-0.082285745,-0.062845745,-0.059073358,-0.090931965,-0.060138211,-0.00672643,-0.13746619699999998,-0.008860906,-0.12733884199999998,-0.013121677,-0.15451162,-0.038310904,-0.126260586,1.311443082,2.507118904,-5.424117925,-5.117850403,-4.974972878,-5.585395836,-6.435259682000001,-5.007110825,-5.552981748,-1.835993024,-1452.9501614659093 -4333,4333,K252E,-0.07352229099999999,-0.041302239,-0.033745383,-0.063028645,-0.006253246,-0.018833847,-0.06432579,-0.082718792,0.007874446,0.030374847000000003,-0.112979324,-0.009322283,-0.058168482,-0.012384757,-0.11367253199999999,-0.041920026,0.029413535,1.337439289,2.544722429,-2.7219291689999996,-1.923816208,-2.116819099,-3.233305595,-3.91396402,-2.421740921,-3.833381183,-0.345725204,-1457.2176097808406 -4334,4334,K252D,0.051397687000000004,0.07362913900000001,0.113703883,0.070681037,-0.032738769,-0.012087153,0.096671492,0.006123880999999999,-0.071512054,0.196580647,-0.04932237,0.186757736,0.04065003,0.17748770600000002,-0.036125633,0.051674257,-0.117151795,1.027191307,2.886890522,-2.834574042,-2.269511276,-2.247516113,-4.349159828,-4.416551949,-0.890131042,-3.4479694139999997,-0.945135176,-1452.9263704479672 -4335,4335,K252G,-0.08016205700000001,-0.050035275,-0.036644239,-0.04523371599999999,-0.029883316,-0.0037803040000000004,-0.088717352,-0.07160676099999999,0.012332271,0.0026401659999999998,-0.102710716,-0.009650885,-0.063637592,-0.008171017,-0.082296415,-0.055640817,-0.004125814,1.334159116,2.451291407,-1.962827184,-1.1574125370000001,-1.359059143,-3.0199984360000003,-2.491211426,-1.786454376,-3.444826763,2.362656339,-1455.8381709926762 -4336,4336,K252F,-0.19298726800000002,-0.029184536,-0.082006255,-0.038731126,-0.051141275,-0.114200371,-0.194048113,-0.19192642199999999,-0.078563521,0.132000591,-0.190369663,0.050175019,-0.214187529,0.19188552600000003,-0.269347777,-0.038663273,-0.063619277,1.217639234,2.643709807,-8.378540112,-7.450734695,-8.202617546,-9.628371346,-8.691528801,-7.919448173999999,-7.9398554379999995,-5.726879704,-1452.203909272328 -4337,4337,K252I,-0.010280645,0.002251754,-0.040306875,-0.026807661,-0.06945950599999999,-0.079984477,-0.040325056,0.019763766000000002,0.0032995259999999997,0.028251154,-0.023747646,0.019228115,-0.099841865,0.028550399,-0.08216572,0.006166936,-0.14508594800000002,1.1575645479999999,2.598516951,-6.229108476,-5.708719727,-5.309199509,-7.59294326,-6.050250626,-6.48442926,-6.346698814,-3.0783234239999997,-1453.510602678638 -4338,4338,K252H,-0.02318934,-0.058681820999999995,-0.07468414599999999,-0.054277842,0.020027393,0.036079591,-0.01189539,-0.03448329,-0.005123261,-0.002453154,-0.114910488,-0.07054785400000001,-0.07882043700000001,-0.052929339000000006,-0.055626345,-0.09113528900000001,0.131190075,1.336667236,2.274121794,-2.959212085,-2.765050369,-3.105084679,-2.849462753,-3.474072739,-2.602389885,-3.979316222,-0.7014010359999999,-1458.1128862840123 -4339,4339,K252M,-0.043674400999999995,-0.05764853599999999,-0.037585663,-0.020524079,0.003141287,-0.04663703,-0.036490616000000003,-0.050858185,0.015244958000000001,0.063643129,-0.17894020100000002,0.017916173,-0.093087499,-0.012234456000000001,-0.028813702000000004,-0.009843781,0.016126354,1.258926425,2.5311477940000002,-6.317925389,-5.839417221000001,-6.1213980260000005,-7.463211555,-6.260962105,-5.904638039,-6.289372717999999,-3.4078505789999998,-1457.3965159608051 -4340,4340,K252L,-0.077578773,-0.043162704,-0.005602598,-0.016085631,-0.011493641,0.017671165,-0.073364912,-0.081792633,0.005518674,0.074210033,-0.16053544,0.067890514,-0.07909571,0.084320886,-0.116492148,0.025785876,-0.048773158,1.114435354,2.8029253169999997,-6.305521643,-5.901751633,-6.016930771,-7.50034388,-5.982432617000001,-6.126149315,-6.095260801,-3.07599693,-1449.579341955483 -4341,4341,K252N,-0.096134336,-0.023277807999999997,0.004524684,0.027575053,-0.051558232999999995,0.001423884,-0.065717569,-0.126551103,-0.036434899,0.06557547700000001,-0.112131093,0.136341514,-0.127292146,0.11686024,-0.06171013400000001,-0.008953209,-0.094163256,1.177658364,2.682016338,-2.154297289,-2.074240913,-1.4452569730000002,-2.951576012,-2.832109482,-1.468303062,-2.95487503,-0.737818194,-1456.7111048093066 -4342,4342,K252Q,-0.068663753,-0.08995771699999999,-0.097607995,-0.078815361,-0.035846092,0.031634367999999996,-0.049666672,-0.08766083300000001,-0.062239695,-0.038501102999999995,-0.141414331,-0.05938169099999999,-0.135834299,-0.057058983,-0.10057173900000001,-0.04643767,-0.025254513,1.3523852840000001,2.410872775,-2.383747905,-1.870189278,-2.456371506,-2.249125092,-3.119037865,-2.224015785,-3.1769522869999998,-0.754621653,-1459.6360884690657 -4343,4343,K252P,-0.096829419,-0.072766089,-0.054801683,-0.145968315,-1.765691743,0.044738309000000004,-0.10210816,-0.09155067800000001,-0.006512431,0.00592362,-0.151455798,-0.011460146000000001,-0.098143219,-0.002572565,-0.289364065,-1.561807075,-1.96957641,1.0129924909999999,1.342879475,-4.464865636,-3.7992673569999997,-2.909483688,-6.71058606,-4.633765144,-4.271225929,-5.267360429,-2.098047005,-1448.290852920618 -4344,4344,K252S,-0.047883199,-0.072090165,-0.020917138000000002,-0.033060477000000005,-0.00796242,0.004368757,-0.036084396,-0.059682001,0.013001581000000002,-0.0054428540000000004,-0.138737476,-0.004452895,-0.037381381,0.008085577,-0.07420653,-0.058529081,0.042604242,1.197783426,2.32353848,-2.9359374469999997,-3.0314363560000004,-2.669802269,-3.1700415189999998,-3.093028313,-2.7153787769999997,-3.167373335,-0.7547825640000001,-1455.8568502091803 -4345,4345,K252R,-0.070875587,-0.064565955,-0.053508451,-0.051573274,-0.008504702,0.019017309,-0.072373248,-0.06937792599999999,0.00689685,-0.007440197,-0.121691713,-0.02298216,-0.084034742,-0.018582856000000002,-0.084563692,-0.04708421,0.030074806000000003,1.347542398,2.499341491,-1.2713427990000001,-0.6479580229999999,-1.613501404,-0.9302994840000001,-1.823906342,-1.341048744,-2.457670217,1.415680518,-1459.9258105424233 -4346,4346,K252T,-0.06960172099999999,-0.06284770099999999,-0.032908196,-0.055363587,0.019358697,-0.009995595999999999,-0.059485851,-0.07971759099999999,0.001539934,0.01734889,-0.143044291,-0.011957041000000002,-0.05385935099999999,-0.010835761000000001,-0.09989141300000001,-0.014863896000000001,0.05358129,1.220668345,2.652885092,-3.244180469,-2.8341237180000003,-3.1456022110000004,-4.0503362119999995,-3.014693718,-3.1761464839999998,-3.247074635,-1.455989936,-1455.7440973427147 -4347,4347,K252W,-0.107674551,-0.06465397099999999,-0.059512594,-0.061418439000000005,-0.190188435,0.034723095,-0.105197938,-0.11015116300000001,0.023601386000000002,-0.00599669,-0.123311251,-0.028014549,-0.091010638,-0.045592352,-0.077244525,-0.138047905,-0.24232896399999998,1.414912983,2.238588498,-7.84637086,-6.993026436,-7.351992615,-8.93636734,-8.298633087,-7.651834824,-7.677859637999999,-5.113839542,-1452.873674413655 -4348,4348,K252V,-0.075899315,-0.060956225,-0.042987587,-0.054090333,0.018514735,-0.008826168,-0.082168612,-0.069630018,0.020889991,0.004536879000000001,-0.126449328,0.013636748999999998,-0.099611923,0.008774973,-0.116955639,-0.04098686,0.07801632900000001,1.398183217,2.6027034540000002,-5.3836136020000005,-5.145466751,-4.436731285,-6.4451893689999995,-5.557301047999999,-5.333379555,-5.539175936,-2.4971958340000002,-1456.6950408560224 -4349,4349,K252Y,-0.045335188,-0.02176642,-0.08520125099999999,-0.034060032999999997,-0.124149615,-0.08301449,-0.061634244000000005,-0.029036132000000003,0.013439158,0.06557547700000001,-0.109108316,-0.058184108,-0.112218394,0.032184683,-0.10030474800000001,-0.086450181,-0.161849049,1.324863951,2.368413399,-7.621254179,-6.864759003,-7.593892982000001,-8.503105026,-8.303756218,-6.840757667999999,-6.9356067029999995,-4.459813766,-1450.7563072554767 -4350,4350,P253A,0.012251763,0.004046874000000001,-0.049954887999999996,0.001008075,0.0060981130000000005,0.002563305,0.034396251,-0.009892726,0.019048765,-0.017053484,0.025147232000000002,-0.072545068,-0.027364707999999998,-0.055627577000000004,0.057643727,-0.019307713,0.031503939,1.393583924,2.645540692,-1.183180008,-1.753635544,-1.0685898440000001,-0.862322868,-1.391853096,-0.8394986879999999,-2.421316115,1.412387083,-1462.6716846679337 -4351,4351,P253C,0.055546012,-0.028338737000000003,-0.061890195999999995,0.042706590999999995,-0.305743969,-0.0053568719999999995,0.08034095200000001,0.030751071,-0.06589953,-0.062646809,0.005969335,-0.08943488,-0.034345512,-0.034744383,0.12015756400000001,-0.239671408,-0.37181653,1.478797805,2.087389375,-7.162550005,-7.383469894,-5.414369301,-7.919471489,-8.548474197,-6.546965141,-8.277241158999999,-4.32613577,-1458.9427638878115 -4352,4352,P253E,0.010219978000000001,-0.035728552999999996,-0.043534252,-0.011474643,-0.7171818609999999,0.007644061,0.02985852,-0.009418565,-0.034446622999999996,-0.09293145800000001,0.021474352000000002,-0.071949533,-0.015118971,-0.062274777,0.039325491000000004,-0.493145382,-0.94121834,1.5034402480000002,1.8385867580000002,-3.265970053,-3.9491202010000004,-1.541419968,-4.053112984,-3.7565001369999997,-3.0296969760000003,-3.975587286,0.23453589100000002,-1455.191050471738 -4353,4353,P253D,0.059739638,-0.011943905,0.023833925,0.075834973,-0.716142335,-0.053063988,0.07013533799999999,0.049343937000000004,-0.053861482,-0.028021399,0.004133589,0.019902153,0.027765696,0.044654837,0.10701510800000001,-0.423199334,-1.009085335,0.8306945370000001,1.5197217809999999,-4.064997838,-4.3147150960000005,-2.632504944,-4.784869652,-4.45723037,-4.135669128,-4.922685774,0.587284226,-1455.311887849588 -4354,4354,P253G,0.014790078,-0.0018652620000000001,-0.049057535,0.002782417,-0.466278219,-0.009619127,0.024744547000000002,0.004835608,-0.031698803,-0.023866526000000002,0.020136002,-0.06948186099999999,-0.028633207999999997,-0.042294427999999995,0.047859262,-0.255710732,-0.6768457059999999,1.590887955,2.182387887,-3.819347734,-4.323993485,-2.843828758,-3.4975970839999997,-6.4368558039999995,-1.994463539,-3.983722937,0.43485368799999996,-1448.594143549446 -4355,4355,P253F,0.08637020699999999,0.04552739099999999,-0.030415171,0.042751587,-0.23065470899999999,-0.021286167999999998,0.099053573,0.073686841,0.20582520899999998,-0.043546579,0.13460136,-0.12394150400000001,0.063111163,-0.067574285,0.153077459,-0.263778346,-0.197531072,1.50029886,2.081902257,-8.873667328,-9.000127014,-6.870024422,-9.803485611000001,-10.71438654,-7.980313057,-8.734950608,-5.071265036000001,-1458.7434647353366 -4356,4356,P253I,-0.052900301,0.11142724400000001,-0.0005629319999999999,-0.022065442999999997,-0.22074127,-0.028692014,-0.026009928999999998,-0.079790672,-0.096086603,0.08386577,0.13898871699999998,0.047468435999999996,-0.048594299,-0.069462703,0.025331818,-0.18886222800000002,-0.252620312,1.0882857670000001,1.90400814,-6.516913193,-6.9271157610000005,-4.911028755,-6.550408401,-8.411796066,-5.78421698,-7.170860652999999,-2.8020701939999997,-1459.2736967308447 -4357,4357,P253H,0.050061925,-0.020731181,-0.006215015,0.024640594,-0.214422683,-0.039543166,0.016651223,0.08347262700000001,0.036764458,-0.073884033,0.032421671,-0.051240495999999996,0.038810467,-0.031895146,0.081176333,-0.17040193399999998,-0.258443431,1.4269563269999999,2.188234796,-4.711947948,-4.4371819310000005,-2.842131012,-5.842531395,-6.738975998,-3.698919403,-5.029431052,-0.631755492,-1461.5900594014674 -4358,4358,P253K,-0.092022147,-0.033574459,-0.054573214,-0.040507182999999995,-0.549782588,0.063369012,0.0048484290000000005,-0.188892723,0.088431145,-0.104156124,0.037007206,-0.07889655599999999,-0.030249871,-0.123460624,0.04244625900000001,-0.238758368,-0.860806807,1.510961587,2.0967055219999997,-2.913037788,-3.070343346,-1.426672089,-3.547653954,-4.621201019,-1.899318535,-2.8863490460000003,1.003505347,-1457.102541120723 -4359,4359,P253M,0.011257346000000001,0.062117335,0.042856146,0.055912677,0.013571918,0.020054438,0.041366539,-0.018851846999999998,-0.042366555,0.120359488,0.0038751809999999997,-0.007808219,0.093520511,0.014954031999999999,0.096871321,0.025433382999999997,0.0017104520000000001,1.10740376,2.6695471040000003,-6.381919814,-6.808675606,-5.068576752,-6.370821136,-8.360120987,-5.3014045869999995,-7.353758407000001,-3.55905309,-1462.0361586469226 -4360,4360,P253L,0.054985975,0.016183613,-0.050710886,0.008525789,-0.198231325,-0.008437615,0.054447052999999995,0.055524896,-0.002668142,-0.051648933,0.084016159,-0.111925115,0.010503343,-0.085831741,0.102883318,-0.166853784,-0.229608865,1.489267683,2.216193413,-5.087231546,-5.624578377000001,-3.493128212,-4.831398544,-7.402409355,-4.084643242,-5.850249882000001,-2.407344024,-1459.5463077560998 -4361,4361,P253N,-0.006848344,0.016641298,-0.056580200000000004,0.097143385,-0.39741796700000004,-0.09996572699999999,0.112281499,-0.125978186,0.018594545,-0.018322392,0.051604987000000005,-0.096802314,-0.016358086,0.024505712000000002,0.169781058,-0.301150717,-0.49368521600000004,1.577421983,2.1122256569999998,-4.767049362,-3.783810677,-3.06268428,-6.59066259,-6.174505005,-4.223584259,-5.553341644,-0.7335990040000001,-1456.7652687979862 -4362,4362,P253Q,0.049462871,0.018768349,0.029219521000000002,-0.014594246000000002,-0.396652916,-0.016140171000000002,0.033955874,0.064969868,-0.018417553,0.03454081,0.002995888,-0.000623607,0.059062649,-0.065999914,0.036811422,-0.235513227,-0.557792604,1.47460071,2.099275672,-3.332736195,-3.818956291,-1.7856598430000001,-3.825013626,-5.003486649,-2.230564568,-4.304783016,0.111381239,-1459.9887497210875 -4363,4363,P253S,0.021242384,0.011666626999999999,-0.022071991000000003,0.027149309,-0.227414653,-0.015050787,0.02595522,0.016529548,0.023405588999999997,-0.027351708,0.050684962,-0.06093806400000001,0.016794083,-0.028061983999999998,0.08236060099999999,-0.169561093,-0.285268213,1.340402463,2.111688785,-2.2974713209999997,-2.227312393,-1.1571842270000001,-3.114279068,-2.641502159,-2.3470787580000003,-3.362897701,-0.014898804,-1458.0231113163754 -4364,4364,P253R,-0.01401257,0.000250127,-0.042228405,0.018737438000000002,-0.565616356,-0.017677892,0.007706467,-0.035731606,0.021077841,0.008755427,-0.008255173000000001,-0.035142524,-0.049314285,-0.014739888999999999,0.052214765,-0.26860275899999997,-0.862629952,1.429014611,2.027179926,-3.707861328,-4.537049622,-1.510236343,-4.354681587,-6.0204432070000005,-2.1168958819999997,-4.252243317,1.005104819,-1458.280696931295 -4365,4365,P253T,0.029179069,0.046690771,0.002184782,0.065396688,-0.715523995,-0.045748185,0.030413206,0.027944932000000002,-0.030347032000000003,0.021858982000000002,0.071522559,-0.028366551,0.032736114,0.006250628,0.12454274800000001,-0.357183928,-1.073864062,1.51645171,1.986816098,-3.0528271989999998,-2.831913132,-1.569379105,-3.669974571,-4.9193311689999994,-2.273538017,-4.845598482,0.110036682,-1458.374354371801 -4366,4366,P253W,-0.037056808,-0.030596262000000003,-0.04554463,0.0171003,-1.079928286,0.043655482999999995,-0.028074735,-0.046038881,0.011120805,-0.048948877,-0.012243647,-0.050521588,-0.040567672,-0.014243499,0.048444098,-0.8165514209999999,-1.34330515,0.898412697,1.4184675169999998,-8.975329468,-9.349648933,-6.853794296,-9.876669571,-10.61643506,-8.18009948,-9.538299652000001,-7.362813533,-1461.896127248183 -4367,4367,P253V,0.021819572000000002,0.044654135,-0.047024014,0.066707238,-0.549257937,0.011396641,0.018737277,0.024901866,0.048471333,0.016058476000000002,0.073249793,-0.05801815900000001,-0.036029869,0.004644354,0.128770122,-0.249636947,-0.848878927,1.286508962,1.9345644640000002,-4.785800818999999,-5.177059723,-3.861473328,-4.590934937,-6.702271935,-3.597264175,-5.668579191,-1.8037061419999998,-1460.592883136589 -4368,4368,P253Y,-0.0745008,-0.058527189,0.030254291000000003,0.031478213,-0.29574585600000003,-0.006751381999999999,-0.115947414,-0.033054185,-0.104519771,-0.073884033,-0.043170344000000006,0.004002742,0.05650584,-0.016761403,0.079717829,-0.177187923,-0.41430378799999995,1.544767194,2.303887595,-7.938247844,-7.447140922999999,-5.782701148999999,-9.386935692,-9.808919777,-7.265541679,-7.4464071039999995,-3.1684811739999996,-1455.9899978227913 -4369,4369,S254A,-0.077292263,0.000983708,-0.011320321000000001,-0.008467373,-0.031046557000000002,-0.023272498,-0.051319814000000005,-0.103264712,-0.07277927,-0.014930615,0.016898031,-0.023408427000000002,0.000767785,-0.013541043000000001,-0.003393703,-0.024549009,-0.037544104,1.385481931,2.654527629,-1.12795589,-0.829928703,-1.470694664,-0.647948105,-1.004361473,-1.686846504,-1.3678449959999999,0.538437309,-1466.367036594078 -4370,4370,S254C,0.310455027,-0.007004982,0.037133592,0.06626970900000001,-0.036287842,0.025207875,0.114301004,0.50660905,0.038001544,0.006030164,-0.020040128,0.027525572999999998,0.046741610999999995,0.038016438,0.09452297900000001,-0.023634229,-0.048941455,1.256963482,2.472774749,-5.4967860470000005,-4.049459488,-7.586181007,-4.726432991,-6.1485175629999995,-4.973339188,-5.43698261,-1.797668773,-1457.4296134784818 -4371,4371,S254E,-0.036899554,0.031168168,-0.013442751999999999,0.014938513,0.049921103,0.024241605,0.03242132,-0.106220428,-0.056385240999999996,-0.04216237,0.104498706,-0.065669484,0.038783981,-0.01452663,0.044403655,-0.000777732,0.10061993699999999,1.2700313540000001,2.57458469,-2.275311464,-2.09893573,-2.166376701,-2.6496388090000003,-2.011647804,-2.449958275,-2.429855257,-0.758284086,-1462.3379338476807 -4372,4372,S254D,-0.12638976300000002,0.016349653999999998,0.02597998,0.021326805,-0.07671244299999999,-0.025699132000000003,-0.08366295,-0.16911657600000002,-0.029026872000000002,0.049999355,-0.017300047,0.011272283000000001,0.040687677,0.027890468999999998,0.01476314,-0.006025949,-0.14739893699999998,1.172658877,2.5299513719999998,-4.684418915,-3.650573128,-5.421602524,-4.458497086,-4.533296173,-5.358125664,-4.881307076000001,-1.772220686,-1461.0794032276608 -4373,4373,S254G,-0.052655547000000004,0.0028985129999999997,0.016510204,-0.0013683579999999999,-0.019009003,-0.0022381289999999997,-0.015467227,-0.089843866,-0.033770192000000004,-0.044732567,0.050529592000000005,-0.032511038,0.065531445,-0.019266923000000002,0.016530208,-0.011016166,-0.027001839,1.1952619359999999,2.412936074,-5.080683073,-3.9800802,-6.4954331970000005,-5.106406624,-4.4109543989999995,-5.410540947,-5.00683039,-1.255956735,-1455.8437312799506 -4374,4374,S254F,-0.11780489300000001,0.051457261,0.023072255,0.042608705999999996,-0.852830984,-0.031193571,-0.058092727000000004,-0.177517058,-0.07567012,0.039758914,0.063155607,0.082724514,-0.036580005,0.10386266699999999,-0.018645256000000002,-0.425648374,-1.2800135940000001,0.595856494,1.438500881,-8.330261441000001,-6.6255947420000005,-10.31722294,-6.750500113999999,-9.413014572,-8.544974838,-5.956460912000001,-2.627009621,-1444.035234221723 -4375,4375,S254I,-0.05661823,-0.007425204,0.015648411,0.010908863000000001,-0.158424919,0.027667099,-0.019645645,-0.093590815,0.052220296,-0.039071293,0.024220885,0.054534992000000004,-0.023238171000000002,-0.047313664000000005,0.06913139,-0.179074913,-0.137774924,1.54949492,2.295877772,-6.413307266,-5.588095711,-6.719466048999999,-6.170454491,-7.098816482999999,-6.489703597999999,-5.363408223,-1.9430444119999999,-1453.7024400783703 -4376,4376,S254H,-0.14316616,-0.032391106,-0.009945834,-0.036929614,-0.08558390800000001,0.022354368,-0.09773569800000001,-0.18859662100000002,-0.025337417999999997,-0.042921626,-0.021860585,-0.069342474,0.04945080599999999,-0.014680426000000002,-0.059178802,-0.066988605,-0.10417921,1.425478475,2.504198249,-6.384943343,-4.006898911,-8.826061722,-5.521926346,-7.1032286760000005,-6.466601058999999,-4.148203262,0.65483358,-1463.945283231791 -4377,4377,S254K,-0.004400338,0.002332747,0.055228118,0.041486487,-0.020201976,-0.013236842,0.11082558,-0.119626255,0.026308294,-0.08791986,0.09258535400000001,-0.023139901,0.133596137,-0.001270367,0.08424334,-0.05072504,0.010321089,1.3722242519999999,2.534436454,-3.912220656,-2.7898872530000003,-4.203199333,-4.258769264,-4.727215233,-3.582032196,-4.073441423,0.055035774,-1462.854284337256 -4378,4378,S254M,0.014182076000000002,-0.013020901999999999,0.086502743,0.050960585999999995,-0.089127927,0.065584637,0.081380934,-0.053016782,-0.00674035,-0.042560988,0.016519185,-0.031740073,0.204745558,0.005569058000000001,0.096352114,-0.093974128,-0.084281725,1.383365659,2.376571656,-7.348018112,-6.188415512000001,-6.8590221179999995,-7.502510902,-8.200231255,-7.989910774,-5.539979402,-2.427726963,-1457.7587701180018 -4379,4379,S254L,-0.128108364,-0.029747237000000003,-0.029201441,-0.056561532000000005,-0.121766338,0.01030016,-0.080694876,-0.175521852,-0.02713321,-0.032744969,-0.026749505,-0.033856076,-0.024546806,-0.031927867,-0.081195197,-0.073077219,-0.170455457,1.4461091719999999,2.479097431,-6.851155567999999,-5.930336562999999,-5.981504997,-6.917216957000001,-8.293844352999999,-7.1328749689999995,-4.661455064,-1.4920711309999999,-1451.5504366513342 -4380,4380,S254N,-0.11607370300000001,0.032984761,0.053035575,-0.016518827,-0.060392050999999995,0.037065539,-0.067589645,-0.164557761,0.014983634,0.01353778,0.052431741,-0.002000404,0.108071554,0.034216772,-0.067254425,0.055763259,-0.176547361,0.961157833,2.6655015509999997,-4.63287961,-3.692384003,-5.7415316160000005,-4.403483856,-5.013109245,-4.313889328,-5.130544424,-1.37988286,-1462.3012539017946 -4381,4381,S254Q,-0.19192203100000002,-0.070223585,-0.019689468,-0.0066666569999999994,-0.011445583999999998,0.085227481,-0.144395188,-0.23944887399999998,-0.0018177070000000002,-0.035129107,-0.10531806199999999,-0.003268418,-0.036110517,0.048743025,-0.062076337999999995,-0.002471212,-0.020419955,1.671448915,3.643209181,-5.084573808,-3.38113076,-6.073376801,-5.507773605,-5.093374237,-5.367213638,-4.2972803530000006,-0.5550621579999999,-1467.4084102166817 -4382,4382,S254P,-0.09495685599999999,0.009868507,0.0013071019999999999,-0.009858871,-1.092810178,0.00704661,-0.056978807,-0.132934904,-0.018359633,-0.024260001,0.043997014,-0.028411304,0.031025507999999997,-0.015586012,-0.00413173,-0.705828329,-1.4797920269999998,0.850535332,1.430519715,-1.38198976,-0.574218079,-1.5302118230000001,-1.114420296,-2.264148735,-1.4269498669999998,-1.873583465,2.769673122,-1459.4473491078243 -4383,4383,S254R,-0.013196531000000001,0.012912136000000001,0.011631754,0.00791608,-0.02496754,0.012445058,-0.030680943999999998,0.004287882,-0.040970108,0.007179036,0.018645236000000003,0.015670646,0.007592860999999999,6.63e-05,0.015765859,0.003777235,-0.053712314000000004,1.112342145,2.40559552,-5.036340324,-2.818049461,-6.141960625,-5.205154694,-5.237223244,-5.779313599,-4.229749675,1.5283865419999998,-1462.6182595440187 -4384,4384,S254T,-0.053628812000000005,0.024137711000000003,0.026426815,-0.026935808999999998,-0.00718497,0.003629904,-0.022896929,-0.084360694,0.002081122,0.00035196699999999996,0.047923454000000004,0.007267404,0.045586225,-0.039285253,-0.014586365,0.014073246000000001,-0.028443186000000002,1.231938942,2.6546723969999997,-1.221565979,-0.965376274,-1.25037841,-1.492573975,-1.26765583,-1.1318454059999998,-2.52171576,0.260172409,-1462.0750873642974 -4385,4385,S254W,-0.08612675800000001,-0.065814395,-0.031431493,-0.041933604,-0.424733032,-0.06300693,-0.009136165,-0.163117351,0.128188344,-0.007969271,-0.12365951800000001,-0.026261392,-0.036601594,-0.043171811,-0.040695397,-0.146355995,-0.703110068,1.39563807,2.214735936,-8.229243013,-6.465822319,-9.753524216,-7.393716789,-8.563747414,-8.969404327000001,-5.677194232000001,-2.8914114719999997,-1453.6529992828146 -4386,4386,S254V,-0.091244487,-0.004765805,-0.02258463,-0.002045327,-0.074877584,0.021425577999999997,-0.052848544000000004,-0.129640429,-0.013734615,-0.03485969,0.02532808,-0.047190175,0.002020915,-0.017494421,0.013403768,-0.040700344,-0.10905482300000001,1.224566242,2.396587879,-4.405721613,-4.012061165,-4.500886276,-4.491062187,-4.130973648,-4.893624786,-4.032980198,-0.545677014,-1458.2256108424626 -4387,4387,S254Y,-0.16885800399999998,-0.08137451799999999,-0.018126134,-0.013225464,-0.6472753139999999,0.089898805,-0.060481899000000006,-0.277234109,0.002483705,-0.110782743,-0.051966293,-0.086302352,0.050050085,-0.067942287,0.04149136,-0.418995125,-0.875555503,1.54175309,1.9502742030000002,-8.201130724,-5.500169571,-11.64448792,-6.505533691,-8.652663627999999,-8.702798813,-5.678352814,-1.017984998,-1450.0912720402703 -4388,4388,R255A,-0.043378499,-0.021511047999999998,-0.031945101000000004,-1.2166784929999999,-2.085895793,0.01367479,-0.052926667999999996,-0.033830329,0.015042969,-0.0047271909999999995,-0.038294904,-0.018390781999999998,-0.045499419000000006,-0.63709957,-1.796257415,-2.058506898,-2.1132846869999997,1.8133363630000001,1.39882025,-6.764009561,-7.458838936,-6.545634781,-5.9664639820000005,-7.151590378,-6.69751973,-5.4170065979999995,0.616571469,-1448.1778821791522 -4389,4389,R255C,-0.020210327,-0.031898994,-0.026925435,-1.112463686,-2.442376616,0.024466855,-0.016416206000000003,-0.024004447999999998,0.058054617999999995,0.005031494,-0.068829481,-0.013214073,-0.040636796,-0.625969636,-1.598957735,-2.132883613,-2.751869619,1.7511951909999999,1.3551677469999999,-8.855382387,-10.32537157,-9.100717941000001,-8.611462105,-7.461926361000001,-8.777433952,-7.026274695,-0.7868193720000001,-1445.245338914916 -4390,4390,R255E,-0.08684752,-0.09743882400000001,-0.166490792,-1.75262398,-2.826118507,-0.067699275,-0.09102025400000001,-0.082674785,-0.014210572,-0.07037572,-0.124501927,-0.08964716199999999,-0.24333442100000002,-1.232235937,-2.273012022,-2.675996114,-2.9762408989999996,0.775369457,0.732449195,-10.56357408,-11.56331415,-10.35561404,-10.412142999999999,-11.56554111,-8.921258102000001,-8.530136,-3.638000043,-1445.0409385948442 -4391,4391,R255D,-0.039089437000000005,-0.90444169,-2.10411754,-2.51920936,-2.5773365790000002,0.014710282,-0.020923762,-0.057255112000000004,0.045977008,-0.403046202,-1.405837178,-2.371060997,-1.837174082,-2.45542186,-2.58299686,-2.537454201,-2.617218957,0.339508504,-0.46896967100000003,-11.12075656,-12.18770659,-10.55042397,-10.67306437,-11.8287181,-10.36386977,-9.405761067,-5.994013933,-1447.5222173226066 -4392,4392,R255G,-0.035516339,-0.019530771000000002,-0.988709271,-1.929591186,-2.607993029,-0.02390448,-0.030780765,-0.040251912,-0.049704622000000004,0.00465833,-0.043719870999999993,-0.44858106200000003,-1.528837479,-1.77640764,-2.0827747309999998,-2.366595469,-2.8493905880000003,1.67396494,0.820922088,-9.823540735,-10.21552294,-10.01343985,-9.269761878999999,-9.988492256,-9.630486748,-7.823932748,-1.89537733,-1451.8504571774974 -4393,4393,R255F,0.023336492,0.009398449,-0.9195616259999999,-1.885576062,-2.8763539939999996,-0.016047875,-0.000824997,0.047497980999999995,-0.049030082,0.08058001599999999,-0.061783119000000004,-0.491628169,-1.347495083,-1.948901035,-1.822251089,-2.252782125,-3.499925862,1.5994211680000001,0.7441130220000001,-6.700698158,-7.297774948,-6.17204464,-6.26757737,-7.3728741,-6.393219734,-5.224133976,2.26768469,-1446.0413920958526 -4394,4394,R255I,-0.05677605,-0.001571475,-0.047934729,-0.296151688,-1.6814741469999999,-0.11027069999999999,-0.157075992,0.043523893,-0.048329183,0.028180258,-0.031323207,-0.017357306,-0.078512151,-0.025329822999999998,-0.566973553,-2.200783849,-1.162164445,0.6938073859999999,1.283077579,-6.17004744,-8.280233871,-5.5209947360000005,-5.557661102000001,-7.311126709,-4.180220779,-3.628858703,3.0138306889999997,-1447.3441618923098 -4395,4395,R255H,-0.029324962000000003,-0.016389397,-0.029693857,-0.47616995100000004,-1.895191031,-0.029426251,-0.043124813,-0.01552511,-0.053482375,0.00028271599999999997,-0.03306151,-0.002237421,-0.057150293,0.005624116,-0.957964017,-1.614926104,-2.175455957,0.592780347,1.309902125,-3.7998659060000004,-3.8010724330000003,-3.650109695,-4.00339782,-4.423513123,-3.1212364580000003,-5.767567696,-1.120295891,-1455.743266040925 -4396,4396,R255K,0.029245342999999997,-0.05690964900000001,-0.082790346,-0.03681639,-0.027408632000000002,-0.033182869,0.003948473,0.054542212,0.011837503000000001,-0.061972562,-0.051846736,-0.009487961999999999,-0.156092729,-0.06422635900000001,-0.00940642,-0.059977113,0.00515985,1.224864098,2.236257546,-6.604129267999999,-6.487511215,-6.709932335,-6.760024948,-6.94784359,-6.115334251,-7.153557987999999,-2.07633807,-1458.140667973552 -4397,4397,R255M,-0.001651074,0.032912732,-0.028043943999999998,-0.245939811,-2.10091888,0.016102622,-0.017103208999999998,0.013801062,0.048355164000000006,0.010065858,0.055759605999999996,-0.076343319,0.020255431,-0.018427231000000002,-0.47345239100000003,-1.648058485,-2.553779275,0.748983301,1.316677466,-7.8767915539999995,-9.229757027,-8.574009911000001,-7.415159111,-8.303513794,-5.861517929,-4.889192212,0.146158974,-1447.5388404438272 -4398,4398,R255L,-0.032645135,-0.026034757999999998,-0.028104442,-0.378602858,-1.841853145,0.036097152,-0.040346072000000004,-0.024944197999999997,-0.009133783000000001,-0.021284214,-0.030785302,-0.009055568,-0.047153315,-0.053666649000000004,-0.703539067,-1.65395977,-2.02974652,0.707906748,1.313784227,-5.912760696,-6.981705872,-7.856859055,-5.39116188,-3.74528701,-5.588789665,-4.0808625869999995,2.723804346,-1446.926238513086 -4399,4399,R255N,-0.014402288000000001,-0.035500676,-1.025941744,-1.85328601,-2.618899902,-0.009017172,-0.016501092,-0.012303483,0.01147398,-0.032706447,-0.038294904,-0.7371536390000001,-1.314729848,-1.997605761,-1.708966258,-2.079638101,-3.1581617019999997,3.578366533,2.24752255,-10.07719632,-10.0060732,-10.40572917,-10.10155185,-11.30015036,-8.57247702,-9.378161197,-5.85321931,-1450.2267053439282 -4400,4400,R255Q,-0.040554365,0.008872005,0.00031886400000000003,-1.258097567,-2.147603701,0.003432691,-0.049386124,-0.031722605,-0.033629801,0.037599935,-0.019855925,0.028709667999999997,-0.02807194,-0.746093405,-1.770101729,-1.782368254,-2.5128391480000003,2.072798894,1.5768677709999999,-6.589488536,-7.422879501000001,-6.996257385,-6.000133591,-6.953653572,-5.574518631,-7.279640937000001,-2.224759213,-1453.5326224854216 -4401,4401,R255P,-0.0070594640000000005,-1.750263954,-2.222086659,-2.2804655190000003,-3.355304615,-0.020685797,-0.021377765,0.007258838,-0.085706332,-1.830525753,-1.670002154,-1.991456736,-2.452716581,-2.110579705,-2.450351332,-2.9707632960000003,-3.739845934,-0.30828932,-1.0981262390000002,-11.0943509,-11.60364522,-11.20846322,-10.58815392,-11.53673878,-10.53475333,-9.405761067,-5.994013933,-1446.4240574813448 -4402,4402,R255S,-0.01805155,-0.003711798,-0.024266617999999997,-1.248414034,-2.797274372,-0.014074366999999999,-0.017392992,-0.018710108,-0.023558977999999998,-0.016855271,0.009431676,-0.023265532999999998,-0.025267702000000003,-0.8048201420000001,-1.692007926,-2.701987299,-2.892561445,0.798030178,0.790074973,-8.947214819,-8.844811722000001,-8.350699028,-8.574395492999999,-9.854117287000001,-9.112050567999999,-7.292145709,-2.297251214,-1447.2893555881456 -4403,4403,R255T,-0.002236586,0.004703486,-0.072025036,-1.067756336,-2.500235922,-0.077486434,-0.017656074,0.013182902,-0.035228051,0.044229395,-0.034822424,-0.039362182,-0.104687889,-0.467505021,-1.66800765,-2.011935359,-2.988536485,1.689861255,1.3828266130000002,-7.327070472999999,-8.372932175,-6.30394352,-7.0119114,-7.762431702000001,-7.184133567999999,-5.652982322000001,-0.946084923,-1446.3409420032986 -4404,4404,R255W,-0.011575321999999999,-0.6669954579999999,-1.952554295,-2.033142725,-2.741784941,0.054773447,-0.009266896,-0.013883747,0.007532685999999999,-0.255093672,-1.078897244,-1.947716409,-1.95739218,-1.855986013,-2.210299436,-2.415139608,-3.068430274,0.959112405,-0.092401791,-5.317202786,-6.016811287,-5.845949615,-5.247691368,-6.065923088,-3.409638573,-4.450118478,0.47834255600000003,-1448.7010124367662 -4405,4405,R255V,-0.043340984000000006,0.006080136,-0.009585314000000001,-0.26264843,-1.555218978,-0.0067246630000000005,-0.059685679000000005,-0.026996289,0.0018514,0.045123859,-0.032963587,0.035183174,-0.05435380099999999,-0.008278801,-0.517018058,-1.4660982919999999,-1.6443396630000002,0.565240506,1.314980287,-5.568502372999999,-6.840176743,-5.529785744,-4.516499321,-6.297876822999999,-4.658173233,-4.015973635,2.625701946,-1447.7695641960017 -4406,4406,R255Y,-0.001309946,-0.087036091,-1.401495964,-2.5167950980000002,-2.256511268,-0.043019517,-0.0008956639999999999,-0.001724227,0.0565202,0.024387269,-0.198459451,-1.1924951190000002,-1.6104968080000002,-2.00385471,-3.0297354860000003,-2.261978309,-2.251044226,3.124234435,1.6524003859999998,-4.858955217,-5.413916603,-4.329925949,-5.657278549,-5.138023796000001,-3.755631187,-4.463659044,3.2307122089999996,-1448.0073455097154 -4407,4407,I256A,0.051827108,0.032781448,0.028515986,-0.026911959,-1.7805132590000001,-0.007461,0.085134343,0.018519873,0.014202818,-0.013334348999999999,0.078897244,-0.017426233,0.074458205,0.033923297000000005,-0.087747214,-1.5821775040000001,-1.978849013,0.62849743,1.3126328390000002,-7.433812068,-6.496695755,-5.36975872,-12.23994312,-7.306442382999999,-5.75622036,-4.924034397,0.251557375,-1460.3640349954367 -4408,4408,I256C,0.198037186,0.06620712200000001,-0.020877817,0.063026065,-1.213999249,-0.061310116,0.207916109,0.188158262,0.042913202000000004,0.031156301,0.101257943,-0.07282441099999999,0.031068778,0.031302258,0.094749871,-1.3230322,-1.104966297,0.7064284190000001,1.331148838,-9.957338533,-8.111836128,-7.830223701,-13.65027501,-9.297541077,-10.89681675,-6.806913344,-3.8020282260000005,-1458.2881306381896 -4409,4409,I256E,0.005147858,-0.169800372,-1.443462953,-2.4045005180000003,-2.9466816110000003,0.014501176000000001,0.026545742999999997,-0.016250028,0.003828572,0.041374097,-0.38097484,-1.305857327,-1.581068579,-2.392062357,-2.4169386790000003,-3.130096384,-2.7632668380000003,0.47201495,0.05578944,-12.655432800000002,-11.06546815,-9.927366623,-16.17915937,-11.86462607,-14.24054379,-7.205438059,-4.3833381010000005,-1458.709523523692 -4410,4410,I256D,0.103227099,-1.7086673369999998,-1.665553438,-2.411804575,-2.347045758,-0.043637456,0.08708009900000001,0.119374099,-0.11336628800000001,-1.276122644,-2.141212029,-1.683607971,-1.647498904,-2.20554157,-2.618067579,-2.3415156059999997,-2.352575909,4.026599353,1.856402392,-13.93676651,-11.8235308,-11.46996103,-17.81575994,-13.22846011,-15.34612065,-8.657203444,-6.396043462000001,-1461.4717772859149 -4411,4411,I256G,0.052258855,0.028385392000000002,-0.757248183,-1.5946151080000002,-2.507533621,-0.049460732,0.077851455,0.026666254,-0.026400958,-0.013208397,0.06997918,-0.41180759299999997,-1.102688772,-1.3904592009999999,-1.798771015,-2.286101082,-2.72896616,2.49432858,1.5001892330000002,-11.485227900000002,-9.447622062999999,-8.45546917,-16.70241387,-11.17613887,-11.64449554,-6.895650516,-3.9015460319999997,-1456.3526052497327 -4412,4412,I256F,0.036034788,-0.014061128999999999,-0.049811852999999996,-0.010366645,-1.443576474,-0.041818615,0.044981069000000005,0.027088506000000002,0.030505328999999998,-0.05903768400000001,0.030915427000000002,-0.068583002,-0.031040703,-0.0053877740000000006,-0.015345515,-1.400637058,-1.486515889,0.7526660709999999,1.3306146890000001,-4.65080755,-3.05035511,-3.6003967439999998,-7.014225288,-4.731539215,-4.857521393,-4.203818676,-1.6960814919999998,-1451.309251341503 -4413,4413,I256H,-0.021972134,-1.0681758559999999,-2.2196449990000002,-2.216740859,-2.9785882989999997,-0.07486626,-0.060603227999999995,0.016658961,-0.008011118000000001,-0.9459042590000001,-1.190447453,-2.149269603,-2.290020395,-2.495111943,-1.938369775,-2.631085979,-3.3260906180000003,0.566180384,-0.60104993,-13.47177684,-11.87922249,-9.942826744,-16.64503691,-12.14428346,-16.747514600000002,-7.782838145,-5.347386473,-1458.1220170371234 -4414,4414,I256K,0.038237877,-1.798913843,-1.9799437119999999,-2.4831567999999997,-2.778477635,-0.066418375,0.056527047999999996,0.019948705,-0.033396951,-1.825098023,-1.772729662,-2.01870353,-1.9411838940000001,-2.5406371290000003,-2.425676471,-2.852702424,-2.704252845,-0.6658032389999999,-1.079945192,-13.47039813,-11.23474399,-10.72886097,-16.4193326,-11.84661171,-17.12244137,-8.655554336,-6.402563799,-1454.7442494365387 -4415,4415,I256M,0.023897928,0.021976203,0.019730043,0.019270673999999998,-0.857250367,-0.036256949,0.031290881,0.016504974,-0.041787621000000004,0.030489067999999998,0.013463336999999999,0.027548472999999997,0.011911613,0.041148049,-0.002606701,-0.6151655629999999,-1.0993351709999999,0.651828558,1.40046959,-5.291553201,-4.705943512,-4.7874640269999995,-6.685430229,-5.147003478999999,-5.1319247589999994,-5.331084218,-3.3502003960000004,-1463.9641648535617 -4416,4416,I256L,0.062237257000000004,-0.0015447629999999998,0.030183308,0.013804997,0.031781474,-0.031328813,0.07166125200000001,0.05281326099999999,0.013850616000000001,-0.034848385,0.03175886,-0.023670135,0.08403675,0.008429510999999999,0.019180482,-0.067632949,0.131195897,1.3746939669999998,2.393562958,-2.155813625,-1.446231056,-1.917934174,-2.847155426,-2.197679077,-2.37006839,-2.62369923,-0.37424145200000003,-1462.3366561015137 -4417,4417,I256N,0.055310147999999996,-0.562821218,-1.5490889890000001,-2.134230479,-2.785153544,0.002237775,0.024916569,0.085703727,0.041503807999999996,-0.235319632,-0.890322803,-1.606592786,-1.4915851919999998,-2.350375135,-1.9180858219999999,-2.486349171,-3.083957916,1.1475383479999999,0.056500034000000005,-13.0310496,-10.70349392,-10.14103234,-16.84293498,-12.34826796,-15.11951881,-8.127703815,-5.743080662000001,-1460.6132625723258 -4418,4418,I256Q,0.071591266,-0.422695555,-1.6293270069999999,-2.225063146,-3.321413976,-0.026934062999999998,0.071663129,0.071519403,-0.00127215,-0.206701235,-0.638689874,-1.509451211,-1.7492028030000002,-2.177512846,-2.272613446,-3.0124568860000003,-3.6303710660000004,1.143897832,0.09258027099999999,-12.8270351,-10.87824624,-10.06537879,-16.14246511,-10.87328754,-16.17579784,-8.059054463999999,-5.732600856,-1461.1168639888056 -4419,4419,I256P,0.016773053,-1.7050056740000001,-1.9394234890000002,-2.783821948,-2.8640804369999997,-0.013803252,0.027422807,0.006123298,-0.10586845800000001,-1.811646915,-1.598364432,-1.845551579,-2.033295399,-3.004307275,-2.563336621,-2.8392513160000004,-2.888909558,-0.076987674,-1.0948079309999998,-11.80632752,-10.51545722,-9.405980995,-15.86023612,-11.12081293,-12.12915034,-7.856497326,-5.6505433410000006,-1447.9384260117076 -4420,4420,I256S,0.013634515,-0.09314712,-1.3456166330000001,-2.033570791,-2.7213869639999997,-0.025374945,0.030277408999999998,-0.00300838,-0.05700068,0.030353638999999998,-0.21664787800000002,-1.064450768,-1.6267824969999998,-1.987529516,-2.079612066,-2.600624807,-2.84214912,2.2374351480000003,0.9071752059999999,-10.03763713,-7.948071854,-7.537128479,-15.13409908,-9.138651497,-10.43023474,-6.506612854,-2.448623204,-1457.4404842508957 -4421,4421,I256R,0.024502272999999998,-1.7659977580000001,-2.034737441,-2.223594437,-3.003933659,-0.038277322,0.056633267,-0.007628721999999999,-0.101842839,-1.69165777,-1.840337745,-2.213086449,-1.8563884330000002,-2.111770758,-2.335418115,-2.694902825,-3.312964493,-0.21540336100000002,-1.0851002570000001,-14.00122744,-11.31260469,-10.91593624,-16.80795244,-12.68227671,-18.28736711,-8.739979436,-6.402563692,-1449.3584565422498 -4422,4422,I256T,0.043519472000000003,-0.028753043,-0.12651782,-1.80799367,-2.782825476,-0.036170131,0.054606880999999996,0.032432062000000005,-0.01449531,-0.060331857999999995,0.0028257729999999997,-0.053096995999999994,-0.199938644,-1.457112201,-2.158875139,-2.3712374869999997,-3.1944134639999997,0.856921096,0.720312134,-8.259118475,-6.6865898360000005,-6.272687027000001,-11.2548152,-7.358060715,-9.723439597999999,-5.733026662,-1.829980766,-1458.045418197289 -4423,4423,I256W,-0.0020921810000000002,-0.40051956200000005,-1.540245048,-2.117686485,-2.8866541430000003,-0.014054038999999999,0.013850848,-0.018035209,0.018394191,-0.11983741,-0.6812017140000001,-1.525344171,-1.555145924,-2.213609192,-2.021763777,-2.3495832269999997,-3.4237250589999997,0.859555605,0.045686776,-10.865573399999999,-8.677658821,-9.192047974,-13.90670571,-10.70988857,-11.84156593,-8.075393361,-6.07463222,-1451.187992184423 -4424,4424,I256V,0.08197183400000001,0.037195419,0.043297259000000005,0.054170102000000005,0.061372290999999995,-0.012270831999999999,0.10678802300000001,0.057155644000000005,0.028964366000000002,0.052220008,0.022170829,0.002612947,0.08398157,0.062097867,0.046242335999999995,-0.010173374,0.132917955,1.168857941,2.575663944,-3.1530383160000004,-2.0792405780000003,-3.033088989,-4.514507225,-5.044824028,-1.093530762,-2.8395217539999997,0.693272718,-1464.0928432624787 -4425,4425,I256Y,0.075536046,-0.04869162,-0.048438367999999996,-1.681059859,-2.204346671,-0.039112489,0.063124083,0.08794800900000001,-0.06038807400000001,-0.042844433,-0.054538807,-0.074369395,-0.022507341,-1.080602833,-2.281516884,-2.216576869,-2.192116473,2.124409129,1.4019804530000002,-7.661777954,-5.80120108,-5.262743782,-9.73363813,-7.3398887329999996,-10.17141805,-5.625650022,-1.337598181,-1450.3868729062378 -4426,4426,V257A,-0.062846113,0.009135987,-0.025366832000000002,0.038927332,-1.3430452380000002,-0.080772329,-0.089593884,-0.036098342,-0.021947092,0.06083327400000001,-0.042561300999999996,0.002038745,-0.052772409000000006,0.0513436,0.026511062999999998,-0.994964153,-1.691126322,0.564277681,1.338527944,-2.714186549,-3.4624953769999998,-1.971668983,-1.875369057,-3.9934857860000004,-2.2679135440000002,-2.875520186,-1.41286227,-1465.9891903721727 -4427,4427,V257C,-0.02382735,0.01253483,0.014347871000000002,-0.006045966999999999,-0.455446835,-0.075916292,-0.030958596,-0.016696103,-0.017814177,-0.004335815,0.029405473999999997,-0.015978525,0.044674266,-0.044724393,0.032632458999999996,-0.27995319399999996,-0.630940475,1.6528467230000001,2.193288383,-8.768818382000001,-9.036265372999999,-8.600427231,-7.191651267999999,-9.474199593,-9.541548447,-7.161952692000001,-4.872525793,-1466.170583365485 -4428,4428,V257E,-0.041742284,0.01345266,-0.9084242790000001,-1.9841138680000001,-2.441804656,-0.08884540199999999,-0.05954282599999999,-0.023941741000000002,-0.043445341,0.048502275,-0.021596956,-0.37636918700000005,-1.44047937,-2.0923466569999998,-1.8758810780000001,-2.388531883,-2.495077428,1.3774376730000002,0.673649424,-9.501699553,-9.584389465,-8.739932807999999,-8.268553123,-10.51002628,-10.40559608,-8.51471993,-6.90408859,-1463.4265890833922 -4429,4429,V257D,-0.082873453,-1.353018439,-2.243443264,-2.512696794,-2.984401943,-0.129990974,-0.099693735,-0.06605317,-0.036376228999999996,-1.025896326,-1.680140552,-2.406646061,-2.080240466,-1.99877189,-3.026621697,-2.595987111,-3.372816775,0.5880825470000001,-0.6391257779999999,-10.71917166,-11.31560867,-9.969042465,-9.304372047000001,-11.23815971,-11.7686754,-9.320356452,-9.424452596,-1472.218841154594 -4430,4430,V257G,-0.044010180999999995,-0.358524952,-1.735548553,-2.342862979,-3.164053131,-0.083181745,-0.06636035400000001,-0.021660007000000002,-0.063625609,-0.051807844000000006,-0.66524206,-1.559547781,-1.911549324,-2.068127559,-2.6175983990000002,-2.489251521,-3.83885474,0.6972807759999999,0.02854432,-9.091801323,-9.664670334,-8.116621559,-7.763987052999999,-9.668850479,-10.24487719,-7.019112354,-4.187521179,-1469.642714283429 -4431,4431,V257F,-0.004322956,0.030132396000000002,0.040317763,-0.761731632,-2.091013819,-0.155540575,-0.014798673,0.006152761999999999,-0.03512635,0.059587027,0.000677764,0.067734713,0.012900812,-0.179758941,-1.3437043219999998,-1.882889662,-2.299137976,1.1274151140000002,1.325951007,-8.226717221,-10.08991094,-8.058535857999999,-6.417245857,-8.096517044,-8.471376403999999,-5.324322302,-1.944202156,-1460.4288722034544 -4432,4432,V257I,-0.008981849,0.057217542999999996,0.044391774,0.077527434,0.058652177,-0.123336658,-0.051078701,0.033115003999999996,-0.06374737400000001,0.041785392000000005,0.072649694,0.050876883,0.037906664,0.026386116,0.128668752,0.010106017,0.10719833599999999,1.217427388,2.698016862,-1.9317574919999998,-1.744709969,-0.834241707,-2.929900665,-2.756873085,-1.393062035,-3.886400098,0.022869919,-1462.6743303597905 -4433,4433,V257H,-0.08031033900000001,-0.436173308,-1.7425183880000001,-2.085803186,-3.009053329,-0.129793569,-0.069814685,-0.090805993,-0.054598867999999995,-0.12907447800000002,-0.7432721379999999,-1.501706323,-1.9833304530000002,-2.22416592,-1.9474404509999999,-2.6452898830000002,-3.372816775,0.902334284,0.055703275999999996,-11.80556571,-11.92361539,-11.95006438,-10.44299136,-11.56061842,-13.15053901,-9.320356452,-9.424453515,-1468.4221916045062 -4434,4434,V257K,-0.086502358,-1.5634696080000001,-2.065668699,-2.232862238,-2.792613017,-0.10159075,-0.051710264000000006,-0.121294452,-0.017542764,-1.4760949380000001,-1.6508442769999998,-1.902602163,-2.228735235,-2.448970501,-2.0167539740000002,-2.569064469,-3.016161565,0.062924703,-0.891421928,-9.652694594,-10.24142681,-9.338001678,-8.076927246,-9.939060051,-10.66805718,-8.052853102,-6.082410643999999,-1466.592785490211 -4435,4435,V257M,-0.08843854599999999,-0.02629171,-0.06921277099999999,-0.21128803899999998,-1.704118253,-0.089092903,-0.080417006,-0.096460085,0.018984900000000002,0.005467643,-0.058051062,-0.030398812,-0.10802673,-0.040551211000000004,-0.382024866,-1.648169194,-1.760067311,0.8025795929999999,1.318570145,-4.270540999,-5.367645096,-4.818829353,-2.060260826,-4.518345139,-4.58762458,-3.576214555,-1.927183307,-1470.8995464383624 -4436,4436,V257L,-0.028215561,0.000320649,0.006455306,0.026319666000000002,-0.6817602559999999,-0.097560527,-0.015758036,-0.040673085,0.004828397,0.0355556,-0.034914302,0.002410574,0.010500037,-0.014851498000000001,0.06749083,-0.37987784799999996,-0.9836426629999999,0.75828416,1.49911456,-4.491599248,-4.541692436,-4.5454288410000006,-3.27125058,-4.596743813,-5.502880568999999,-3.5094055639999997,-0.04004435,-1466.734813814517 -4437,4437,V257N,-0.068721636,-0.058192795,-1.427418495,-2.074132729,-2.696352876,-0.10958702099999999,-0.077363985,-0.060079287,-0.12111191,0.075552175,-0.19193776399999998,-1.118640867,-1.736196122,-1.555864735,-2.592400722,-2.153079957,-3.239625795,3.727471903,2.413897355,-10.86052006,-11.26527186,-10.86047649,-9.106927582,-10.81933268,-12.25059168,-9.320356452,-9.424451693,-1470.090217993129 -4438,4438,V257Q,-0.035185518,-0.462269761,-2.050790248,-2.28315067,-2.905370818,-0.056762927000000005,-0.034089646,-0.03628139,-0.05762683,-0.135361379,-0.789178142,-2.050889082,-2.050691413,-1.81910617,-2.74719517,-2.416321392,-3.3944202430000003,0.70545624,-0.16682196400000002,-10.52989763,-11.07927316,-9.956786301000001,-8.72244664,-11.01993928,-11.87104279,-9.320356452,-9.424452843,-1466.919819870498 -4439,4439,V257P,-0.042546460999999994,-1.8507884019999998,-1.9670615219999998,-2.2676060430000002,-2.898690575,-0.08021822,-0.063755297,-0.021337625,-0.09366510800000001,-1.890874014,-1.81070279,-1.974958559,-1.959164484,-2.307447077,-2.227765009,-2.72857104,-3.0688101089999997,-0.207186864,-1.1233923670000001,-10.26252365,-10.90929496,-10.01629845,-8.924765327000001,-10.44028224,-11.02197726,-9.294577263999999,-9.2852372,-1464.8022876763716 -4440,4440,V257S,-0.033437742,0.013148696000000001,-0.08784237199999999,-1.6313238369999998,-2.146463024,-0.125518259,-0.019530225,-0.047345258,-0.031020072000000003,0.047099543,-0.020802151,-0.009979215,-0.165705529,-1.277111134,-1.9855365390000002,-2.0069519209999997,-2.285974126,2.435679438,1.628918756,-8.553231488,-8.782029839,-7.6706351779999995,-7.282049338999999,-9.010026031,-10.02141705,-8.035250224,-6.217817909,-1463.3308938327245 -4441,4441,V257R,-0.040648226,-1.69158832,-2.100052307,-2.5129266919999997,-3.1921185160000003,-0.11048057800000001,-0.05641681,-0.024879642,-0.142539584,-1.611560425,-1.771616214,-2.02103431,-2.179070303,-2.727103492,-2.298749892,-3.0232887180000003,-3.360948314,0.02435984,-1.059920302,-10.83918245,-11.79571456,-10.22910677,-8.811691681000001,-10.97670217,-12.38269705,-9.320356452,-9.42445405,-1459.2816643938422 -4442,4442,V257T,-0.022687517999999997,0.031765812000000004,-0.003675796,0.033407879,-1.444969154,-0.10287835099999999,-0.045372996,-2.04e-06,-0.018304145,0.04537680400000001,0.018154819,-0.005998705,-0.001352887,0.016524585,0.050291173,-1.2401521,-1.649786208,0.641690298,1.3310518390000001,-5.481109235,-5.969787338,-4.398807648,-4.725731224,-6.2302119220000005,-6.0810080410000005,-5.837710362,-5.132698545,-1463.164356349036 -4443,4443,V257W,-0.010309486999999999,-0.130065334,-1.3208074779999999,-2.364907408,-3.09805193,-0.077496879,-0.004148059,-0.016470915,-0.054790822,-0.000988975,-0.259141692,-1.209135778,-1.4324791769999998,-2.46871456,-2.261100255,-2.588808527,-3.607295333,0.6928074209999999,0.08391108,-9.099029944,-10.74026165,-9.694339127000001,-6.824430244,-7.136149147,-11.09996955,-6.736472432999999,-4.8482505719999995,-1468.1478335070424 -4444,4444,V257Y,-0.033432459,0.026914689,0.004857024000000001,-0.599132978,-2.1445361519999997,-0.1557989,-0.018161972,-0.048702946,0.014009988000000001,0.02936388,0.024465498,0.034009647000000004,-0.024295598999999998,-0.136029831,-1.062236124,-2.168168628,-2.1209036759999997,0.983218865,1.292517849,-9.763068236,-10.91373839,-9.916742836000001,-7.6592910000000005,-9.584347031,-10.74122192,-6.362736685,-3.835443549,-1463.3762548561208 -4445,4445,V258A,0.011156456,-0.037557101,-0.012404448,-0.010520429,-0.177366222,0.008301585,0.022968355,-0.000655443,-0.0035249559999999997,-0.09853407,0.023419869,-0.09389259400000001,0.069083699,-0.09726330300000001,0.076222446,-0.158922167,-0.195810276,1.254158012,2.057825486,-1.9113005580000002,-1.5560618590000002,-2.143498047,-1.959875732,-3.257089104,-0.63997805,-2.174253353,1.171373905,-1465.5389120527543 -4446,4446,V258C,-0.018717432,0.009073619,-0.007921426,-0.011224001,0.008712791999999999,-0.061409171,-0.035445372,-0.001989491,0.041428406,0.002253585,0.015893653,-0.037539324,0.021696472,-0.066794656,0.044346655,-0.005867424,0.023293007,1.197048079,2.424241261,-4.712414476,-5.781599723999999,-5.057299484,-6.202072144,-5.25176429,-1.269336739,-3.8379220239999996,-1.320999984,-1461.2090511238202 -4447,4447,V258E,-0.015774562,-0.944824207,-1.60816998,-2.0144356969999997,-2.065323516,0.014432216999999999,-0.01810288,-0.013446244,0.13120469699999998,-0.7142131359999999,-1.175435278,-2.067992024,-1.148347935,-2.145255082,-1.8836163119999998,-2.193191676,-1.9374553559999999,0.325773789,-0.549919549,-9.812441168,-10.94028965,-9.141573326,-10.40591979,-10.52433689,-8.050086182000001,-8.869157542,-8.970034247000001,-1472.7575399735942 -4448,4448,V258D,-0.068870506,-0.470390938,-1.5694502000000001,-2.5021420709999997,-2.373518919,0.072621793,-0.034412259,-0.10332875300000001,-0.015472941,-0.152416325,-0.78836555,-1.30207523,-1.8368251690000001,-2.282428275,-2.7218558660000003,-2.330364869,-2.4166729680000003,1.28111415,0.173289599,-10.27886536,-11.60921671,-9.857236145,-11.00237828,-10.78362315,-8.141872498,-8.869157542,-8.970034247000001,-1476.3454680959694 -4449,4449,V258G,0.023264172000000003,-0.009486249,0.028035025,-0.028698542,-1.458193585,0.021480389,0.054493424000000006,-0.007965081,-0.067281039,-0.072737257,0.05376476,-0.033343177,0.089413227,-0.015739965,-0.041657118,-1.4455297480000002,-1.470857422,0.6401042920000001,1.320111614,-6.36409883,-8.148089622999999,-4.638996719,-7.801269997,-7.068557281,-4.163580528,-4.628691125,-1.652321088,-1465.6518489210866 -4450,4450,V258F,-0.02695794,-0.072463513,-1.0163347740000002,-1.912312187,-2.973794655,0.014139711999999999,-0.012327423,-0.041588456,-0.011507600000000002,-0.11226802300000001,-0.032659002,-0.640933468,-1.39173608,-1.900040114,-1.924584259,-2.646946712,-3.300642598,1.9030552090000001,0.8398958409999999,-8.159495698999999,-8.178966293,-7.291431519,-10.23924332,-8.229853546000001,-6.857983817999999,-7.456535221,-5.28664883,-1454.9615244357847 -4451,4451,V258I,0.025468746,0.0059036259999999995,0.046390745,0.057771834,0.08894501,0.011885737,0.027616647,0.023320845,-0.05705482,0.037067969,-0.025260717999999998,-0.045019172,0.137800661,0.011466028,0.104077639,0.026722574,0.15116744599999998,1.122961387,2.648329456,-2.837062004,-3.272535721,-2.635758049,-3.103370132,-2.60539283,-2.568253288,-4.443180197,-2.820512789,-1459.1790397055447 -4452,4452,V258H,-0.023263238999999998,-1.746735511,-2.124489571,-2.492014558,-2.84051266,0.018897637,-0.0028694429999999997,-0.043657035,-0.055560841,-1.615230115,-1.878240907,-2.64449791,-1.6044812309999998,-2.721760969,-2.262268146,-2.167637572,-3.513387748,-0.178746375,-1.0480456470000001,-10.76859557,-12.46103688,-10.15658785,-12.14659917,-10.82327518,-8.255478775,-8.869157542,-8.970034247000001,-1466.659598207567 -4453,4453,V258K,-0.108847708,-1.749487373,-2.189710801,-2.131267056,-2.454188897,0.09791333,0.035919825,-0.25361524,-0.12450232,-1.9037435530000002,-1.595231193,-1.978768839,-2.400652763,-2.056031897,-2.206502214,-2.103968492,-2.804409302,-0.513134159,-1.157154373,-9.697293892000001,-11.09576365,-8.75182576,-10.46795579,-9.957396942,-8.213527321,-8.869157542,-8.970034247000001,-1474.982850256376 -4454,4454,V258M,0.044475455,-0.018800871,0.063767046,-1.5518667240000001,-1.7785477280000002,-0.027442312000000003,0.085426914,0.003523995,-0.049800065,-0.13028352199999998,0.09268178099999999,-0.080370072,0.207904163,-1.26899906,-1.834734387,-1.9537577519999998,-1.6033377030000002,2.8023166739999996,1.924474037,-7.292954982,-7.653502045,-7.290457862999999,-7.360493422999999,-7.459300461000001,-6.701021118,-8.071640502000001,-6.3590885870000005,-1462.3447366789915 -4455,4455,V258L,-0.042224828,-0.016140287,0.0028722920000000002,-0.10385262,-1.794191325,0.034355759,-0.0006673180000000001,-0.083782337,0.0014563179999999998,-0.066058377,0.033777804,-0.075365248,0.081109832,-0.058993647999999996,-0.148711591,-1.567765466,-2.0206171840000002,0.8731266609999999,1.329927128,-5.37998071,-5.845997665,-5.186815826,-6.1187465439999995,-5.438030716,-4.310312798,-6.631345636,-4.442615867,-1452.2086340412498 -4456,4456,V258N,0.014440328999999998,0.028436231,-1.484851215,-2.019225758,-1.8571292119999998,-0.009163236,0.055335370999999994,-0.026454712999999998,-0.03533557,-0.073622669,0.130495131,-0.632018159,-2.337684271,-2.071009053,-1.967442463,-2.118945648,-1.595312775,1.7457844319999998,0.746845854,-9.400452722,-10.86129948,-9.209705589,-10.35011768,-9.414715408,-7.166425453,-7.4690535989999995,-6.181368523,-1471.7654734496027 -4457,4457,V258Q,-0.02099978,-1.426388455,-1.74957028,-2.230717157,-2.7041539969999997,0.00826016,0.050375669000000005,-0.092375228,0.008256798000000001,-1.035164417,-1.8176124919999999,-1.779196484,-1.719944075,-2.0325508009999997,-2.428883513,-2.3815173919999997,-3.0267906019999997,3.5611344789999997,1.5225461580000001,-9.587688527000001,-10.85359924,-9.264304085,-10.06813582,-9.748970642,-8.003432854,-8.869157542,-8.970034247000001,-1471.3228807933629 -4458,4458,V258P,-0.018105437,-1.57710817,-2.189313586,-2.289391174,-3.324957823,0.016651186999999998,-0.009673209,-0.026537665,-0.04318869,-1.6629358369999998,-1.491280502,-2.462866862,-1.91576031,-2.3318539780000003,-2.246928369,-2.856911827,-3.793003819,-0.452402176,-1.070980582,-10.03341904,-10.80267217,-10.13754273,-10.62183828,-10.41294646,-8.192095542999999,-8.869157542,-8.970034247000001,-1465.8221935001202 -4459,4459,V258S,-0.037276498,-0.010526519,0.015465571000000001,-0.45423112200000004,-1.671132712,0.030478504,-0.025397057999999997,-0.049155937999999996,0.005072538,-0.041478483,0.020425445,-0.043322384000000005,0.074253525,-0.15995251900000002,-0.748509724,-1.606371651,-1.7358937730000001,1.06534406,1.346040079,-3.355622102,-4.493235024,-3.188994019,-4.722121445,-3.077992966,-1.295767059,-3.1011880260000004,-0.157095319,-1470.5929130171426 -4460,4460,V258R,-0.041351078,-1.4654872380000001,-2.213527065,-2.188556715,-3.037054817,0.032889579,-0.031125887,-0.051576269,-0.036773783,-1.539075323,-1.391899152,-2.551952703,-1.875101427,-2.328185765,-2.0489276640000003,-2.8532436139999997,-3.22086602,-0.036481562,-0.995451062,-9.985415871,-11.22357582,-10.02437411,-10.35377822,-10.09021977,-8.235131432000001,-8.805311322,-8.514037598,-1468.9619747381657 -4461,4461,V258T,-0.047506797999999996,-0.016114093,0.014154373,0.013067529,-1.1459766470000001,0.051724857,0.0058973969999999995,-0.10091099199999999,0.015556037,-0.055058595,0.02283041,-0.053657570999999994,0.081966316,-0.052562690999999995,0.078697749,-0.9138248809999999,-1.3781284130000002,0.792041702,1.379230711,-2.6323029680000003,-3.191543633,-2.712428177,-2.5485476680000003,-2.600726822,-2.108268539,-3.3899248560000004,-0.5984542420000001,-1468.6907108384185 -4462,4462,V258W,-0.029627458,-1.795899454,-1.775713506,-2.027164139,-2.404658216,0.050350679,0.036169487,-0.09542440199999999,-0.09478598699999999,-1.659752058,-1.93204685,-1.813958591,-1.73746842,-2.2891616569999997,-1.7651666209999999,-2.337098252,-2.472218179,0.040061397,-1.032369719,-10.02960909,-10.94091104,-9.656170303,-10.88805606,-10.44906258,-8.213845451000001,-8.869157542,-8.970034247000001,-1456.522421515081 -4463,4463,V258Y,-0.015492551,-0.7179683859999999,-2.153804852,-2.245876105,-2.568797946,0.011824267,0.02570579,-0.056690892,0.050936355999999995,-0.478861916,-0.957074856,-1.943053287,-2.3645564169999997,-2.020316345,-2.471435864,-2.068252939,-3.069342953,4.08046577,2.19523157,-9.03190869,-10.14858277,-8.705362373,-10.49649725,-8.720519714,-7.088581345,-6.236381337999999,-3.445007873,-1455.4684496377595 -4464,4464,I259A,0.016237689,-0.025813887999999997,0.035557073,-1.026115602,-2.396194248,-0.032112264,0.005434207,0.02704117,0.011290742,-0.027770568,-0.023857207999999998,-0.011335246,0.082449391,-0.433967039,-1.618264164,-2.050303389,-2.742085107,1.5928464409999998,1.359157264,-7.972255014,-7.383323166,-8.911997299,-7.047999474,-7.844159232999999,-8.673795898,-3.4176449960000004,-0.578165791,-1456.5293230614625 -4465,4465,I259C,-0.006617213,-0.068404834,0.066826207,-0.035567417000000004,-0.834334283,-0.022547674,-0.006054812,-0.007179614,0.034801219,-0.09341334,-0.043396327,0.047171642,0.086480772,-0.004821698,-0.066313135,-0.452707915,-1.2159606509999998,1.383714249,1.8054317569999998,-10.46375344,-9.69413871,-11.56035831,-11.23857656,-9.833451538,-9.992242065,-6.0904621070000005,-3.0226072860000004,-1459.1214123233221 -4466,4466,I259E,-0.019133861000000002,-1.265967529,-2.088537371,-2.019912975,-2.540625964,0.0044718629999999995,-0.023127118999999998,-0.015140603,-0.036222202,-0.9014805920000001,-1.630454465,-2.157458693,-2.019616048,-2.225210477,-1.8146154719999998,-2.8011676660000004,-2.280084261,0.668318405,-0.577704193,-12.51036276,-12.0451253,-13.34469574,-13.00482675,-11.55085026,-12.60631576,-8.61243677,-5.3556558,-1451.6433602785692 -4467,4467,I259D,0.040952266,-1.915802737,-2.418448303,-2.703221578,-2.877019385,-0.037897667,0.045847857,0.036056674,-0.132890139,-2.348850319,-1.4827551540000001,-2.099678442,-2.737218163,-2.468460222,-2.937982934,-2.567296156,-3.1867426130000003,-0.28626015899999996,-1.204060364,-14.38683522,-13.67070865,-15.81508936,-14.95836974,-13.13573602,-14.35427232,-10.22716526,-9.272965999,-1455.753965113312 -4468,4468,I259G,-0.017523743999999997,-0.6581561029999999,-1.863252469,-2.206128201,-2.671910904,0.00344842,-0.021381534,-0.013665953,0.019773286,-0.375386435,-0.940925771,-1.9408826430000001,-1.785622295,-2.173444675,-2.238811727,-2.483133975,-2.860687832,1.34474071,-0.030459264,-12.13163427,-11.57221709,-13.18489487,-12.425702000000001,-11.33777472,-12.13758268,-7.175415298,-4.068156467,-1463.4809402576648 -4469,4469,I259F,0.003265234,0.00100186,0.057359127,0.005161446,-1.4583354290000001,-0.029165576000000002,0.02166431,-0.015133843000000001,0.082530252,-0.0442261,0.04622982,0.005373421,0.109344833,-0.042723675,0.053046567,-0.8144268109999999,-2.1022440469999997,0.862141721,1.4093352069999998,-7.734231497000001,-6.144914345,-8.051635185,-8.606619965,-8.954379356,-6.913608635,-7.19455713,-2.8159545689999996,-1463.6869973931462 -4470,4470,I259H,0.015779556,-0.823558578,-1.9718392230000001,-2.370234389,-2.845062192,0.019226563999999998,0.011014653000000001,0.020544458999999998,0.018575698,-0.533099373,-1.114017783,-2.0523189090000002,-1.8913595369999998,-2.296161952,-2.444306826,-2.696027882,-2.994096501,1.260323391,-0.176947155,-14.33454303,-13.01536629,-15.57749876,-15.03004639,-13.5592801,-14.49052362,-10.19652198,-9.062989929,-1456.8123466339894 -4471,4471,I259K,-0.028800403,-1.547613779,-2.426923178,-2.561181455,-2.584464264,-0.06389963,-0.065511431,0.007910626,-0.078777246,-1.703190943,-1.392036614,-2.232170317,-2.621676039,-2.299922101,-2.8224408089999997,-2.398758035,-2.770170493,-0.19334162800000002,-1.0826168379999999,-13.30298466,-12.62842825,-14.78173351,-13.57881761,-11.75959104,-13.76635291,-10.22716526,-9.272965955,-1456.6480310526676 -4472,4472,I259M,0.022019825,-0.039318208,0.090268359,0.04617153400000001,-0.36692139100000004,0.017065703,0.056467599,-0.012427948999999999,0.018168941,-0.05885645,-0.019779966,0.013643172,0.166893546,0.007573936999999999,0.08476913,-0.306105845,-0.427736936,1.090767595,1.724656547,-5.310280156,-4.773584381,-6.425236496,-5.665681708999999,-5.6336680679999995,-4.053230125,-6.308466682000001,-2.913255139,-1464.0616456437856 -4473,4473,I259L,-0.0074622759999999995,0.00025969,0.027529956,-0.00523087,-0.088470575,-0.033488206,-0.022345154,0.0074206030000000004,0.045298632,-0.034663887000000004,0.035183267000000004,-0.007804996999999999,0.06286490900000001,-0.000654333,-0.009807406,-0.059557038,-0.117384111,1.2533724529999999,2.3210336590000002,-4.09143688,-2.990283882,-3.860269012,-5.243272858,-4.49118837,-3.87217028,-5.654433568,-1.619550644,-1460.5747928223573 -4474,4474,I259N,0.049565474000000005,-0.446270615,-1.96368322,-2.336502125,-2.66081493,0.063155768,0.075020863,0.024110085,0.036559061000000004,-0.291945468,-0.600595761,-1.3981612490000002,-2.52920519,-1.9430342880000002,-2.729969961,-2.342900218,-2.978729641,3.5749364439999995,1.9594710030000002,-13.59589029,-12.92848701,-15.28806849,-13.88114085,-12.54921775,-13.33253734,-10.20928784,-9.184640344,-1458.319932198152 -4475,4475,I259Q,-0.030910939,-0.7653207409999999,-2.0182674819999997,-2.336514152,-2.899387584,-0.047117267000000004,-0.041499923,-0.020321955,0.027822568,-0.466655821,-1.06398566,-2.062581984,-1.973952979,-2.1303337680000003,-2.542694535,-2.530199698,-3.268575469,1.1125292,-0.209410727,-13.34428223,-12.82746543,-14.51832676,-13.91905456,-11.63315151,-13.823412900000001,-10.22716526,-9.272965952,-1457.6034779804759 -4476,4476,I259P,-0.012771635,-1.77422703,-2.02491538,-2.4288082380000002,-2.666364125,-0.003627724,-0.012731263,-0.012812006,-0.026470635,-1.9439865859999998,-1.6044674730000001,-2.162176127,-1.8876546330000001,-2.2920758180000003,-2.565540658,-2.7267038539999997,-2.606024395,-0.880638875,-1.125437005,-13.94016473,-13.3734584,-15.22898036,-13.999257,-13.31833646,-13.78079144,-10.16346523,-8.936462429,-1457.6960812960751 -4477,4477,I259S,-0.030388726,-0.076420429,-1.3235449540000002,-2.1608514480000003,-2.874239878,-0.014004822,-0.035433681,-0.02534377,-0.0027832829999999997,-0.016915456000000002,-0.135925401,-1.118338709,-1.5287511980000001,-2.109075309,-2.212627587,-2.5089412380000002,-3.2395385169999997,2.1647281830000003,0.80986155,-9.955215167,-9.07216584,-11.04022029,-9.507480316,-9.539356903,-10.61685249,-5.969520612999999,-2.9578401530000002,-1461.1385222822428 -4478,4478,I259R,-0.020776963,-1.805524139,-2.1163742130000003,-2.305927346,-2.4954836780000003,-0.028358604,-0.021506404,-0.020047521000000002,-0.043276512,-1.859276862,-1.751771415,-2.212164976,-2.02058345,-2.154978024,-2.456876667,-2.855873949,-2.135093407,-0.42212540600000004,-1.114607254,-13.968493400000002,-13.35059718,-15.03024307,-14.5024239,-12.48565578,-14.47354706,-10.22716526,-9.272965952,-1454.855368389748 -4479,4479,I259T,-0.004504223,-0.027410059,0.023035262,-0.924139011,-1.997076674,-0.072420049,-0.013055454,0.0040470079999999995,0.00425137,-0.066286704,0.011466586,-0.03593069,0.082001213,-0.543672692,-1.3046053290000001,-1.792270946,-2.2018824009999998,1.558161435,1.429467917,-8.359448515,-8.56974353,-8.885516693,-7.953182541,-8.231493842999999,-8.157305969,-6.154932114,-2.617424452,-1458.1049955203198 -4480,4480,I259W,-0.011617458999999998,-0.011031158000000001,-0.110209634,-1.536861215,-2.428120809,0.087064809,0.0086076,-0.031842518,0.036868575,-0.068064452,0.046002136,-0.053706302000000004,-0.166712966,-1.2632213159999999,-1.8105011130000002,-2.2828760040000002,-2.573365614,2.186508487,1.373218162,-13.12530649,-11.96974539,-13.97483553,-14.01323229,-13.08973362,-12.57898563,-10.22716526,-9.272965963999999,-1454.5096966777928 -4481,4481,I259V,0.010544808000000001,-0.005507439,0.040323085,-0.010872965,-0.020923763,0.00767212,0.009911523,0.011178093,0.00353074,-0.040082554,0.029067676,-0.004547454,0.08519362300000001,0.006298475,-0.028044405,-0.046852965,0.005005439,1.3001260479999999,2.6362872040000003,-3.188228323,-3.369792336,-3.20571669,-3.080606033,-3.761401352,-2.5236252059999997,-4.012931183,0.821965532,-1459.6670347615145 -4482,4482,I259Y,0.020915231,0.00499355,0.058215089000000005,-1.053517242,-2.403888322,0.033069463,0.056403079,-0.014572618,0.040681302,-0.07902754099999999,0.08901464099999999,-0.03327005,0.14970022800000002,-0.374728703,-1.73230578,-2.086348494,-2.721428149,1.682577698,1.3833352509999999,-11.99125661,-10.65569012,-13.02053458,-12.81673318,-12.16834022,-11.29498497,-8.86039809,-5.638871063,-1455.7089599738829 -4483,4483,Y260A,-0.07228285599999999,-0.017491337,-0.491232523,-1.71675373,-2.509598383,0.02361869,-0.094517257,-0.050048455,-0.044963468,-0.004654585,-0.030328088,-0.186958185,-0.79550686,-1.4182109840000001,-2.015296475,-2.335708158,-2.6834886069999997,1.2318294440000002,0.78015655,-11.59599843,-10.12865441,-14.36169131,-9.556068932,-10.91927251,-13.014305,-6.66756516,-2.881714221,-1432.9620951106772 -4484,4484,Y260C,-0.05966662,-0.055302440999999994,-0.039341381,-1.00987561,-2.041769272,-0.014622301,-0.101314369,-0.01801887,-0.032125486,-0.049684177999999996,-0.060920703,0.009809075,-0.08849183699999999,-0.45868492899999996,-1.561066291,-1.824405017,-2.259133527,1.693213386,1.427454004,-11.7492586,-12.12689021,-14.02378864,-8.786730064,-10.64636112,-13.16252297,-6.780323556,-2.263819062,-1440.3921825955622 -4485,4485,Y260E,-0.04437061,-0.940282026,-1.9810435069999999,-2.4187266259999998,-2.560872172,0.0019077220000000002,-0.049135613,-0.039605606,0.032999133,-0.5877135370000001,-1.292850514,-2.067701743,-1.89438527,-2.590238389,-2.247214862,-2.9817657410000002,-2.1399786030000003,0.8872767859999999,-0.389100913,-13.23631614,-12.32415756,-15.15885511,-11.69851585,-12.66832561,-14.33172655,-9.516601846,-7.418804548,-1452.1881098281592 -4486,4486,Y260D,-0.12359138800000001,-1.372445532,-1.870817811,-2.46451362,-3.17182605,-0.012991233,-0.165387036,-0.08179574,-0.08519371699999999,-1.10086917,-1.644021894,-1.893625775,-1.8480098459999998,-2.160889916,-2.768137323,-2.728508527,-3.615143573,3.616910363,1.4543220030000001,-14.62173883,-13.48005814,-18.203388600000004,-11.87273505,-14.49698966,-15.05552271,-9.120452536,-6.791117909,-1459.4777478156611 -4487,4487,Y260G,-0.048297163,-0.96498148,-2.049906106,-2.228508013,-2.5964371330000002,-0.010718826,-0.090411006,-0.0061833190000000005,-0.00589641,-0.628918938,-1.3010440220000001,-2.08678728,-2.013024932,-2.169991233,-2.287024792,-2.3241576680000002,-2.8687165980000002,1.25664558,-0.24246105899999998,-13.51905942,-11.93668503,-16.35935231,-11.12224606,-12.70877942,-15.46823428,-7.800460091000001,-4.676206214,-1439.4912095787004 -4488,4488,Y260F,-0.147395519,-0.033552122000000004,-0.040019108,-0.038130585,-0.06715326099999999,-0.060307735999999994,-0.07492516,-0.21986587800000001,-0.072429585,-0.029393473,-0.03771077,-0.024596476000000003,-0.05544174,0.031946592999999995,-0.108207762,-0.021114571000000002,-0.11319195,1.181133305,2.500025061,-3.668141696,-2.41479084,-6.398801376000001,-3.0037127910000003,-3.5659154510000004,-2.9574880219999997,-3.456446068,-0.030094309,-1452.318419973366 -4489,4489,Y260I,-0.09533029999999999,-0.06347942599999999,-0.11914961199999999,-0.06770156,-0.888012503,-0.019439605,-0.039666817,-0.15099378300000002,-0.05307656,-0.104034819,-0.022924032999999996,-0.168995093,-0.06930413099999999,-0.121503214,-0.013899905,-0.45867290299999997,-1.317352102,2.0136666119999997,2.2750290680000003,-12.99707597,-11.17831162,-18.01060628,-11.05781602,-12.68474937,-12.05389654,-7.3168769629999995,-3.08144686,-1434.2075206208974 -4490,4490,Y260H,-0.041080456,-0.18479290399999998,-1.924316066,-2.319041871,-2.685733682,-0.030575232999999997,-0.069174168,-0.012986743,-0.075801374,0.029392027999999997,-0.398977835,-1.692783502,-2.155848629,-2.340258885,-2.297824856,-2.430756241,-2.9407111230000003,0.526761823,-0.0005654459999999999,-8.99707758,-8.240213318,-10.02224867,-7.580214317,-9.633378876,-9.509332718,-7.963764771,-5.437550076,-1453.907904015854 -4491,4491,Y260K,-0.011171246000000001,-0.788743113,-2.703249595,-2.34540041,-2.964667211,-0.141860836,-0.038013281,0.015670788999999997,-0.057196512000000005,-0.48650676299999995,-1.090979463,-2.499371456,-2.9071277330000003,-2.5447868469999997,-2.146013973,-2.6352842030000003,-3.294050218,0.436570016,-0.483639125,-13.38885349,-12.64384152,-16.34126991,-11.46899885,-13.59174181,-12.89841539,-10.00794245,-9.205784858,-1444.4237507646903 -4492,4492,Y260M,-0.073449131,0.029482712999999997,-0.004989957,0.023379691,-0.00915987,-0.11302274300000001,-0.049594482999999995,-0.09730377800000001,-0.038776756,0.010271093,0.048694332,-0.02460752,0.014627606000000001,0.02816632,0.018593062,-0.020474113000000002,0.002154373,1.518083569,2.7533743189999997,-9.783943736,-6.988291771,-14.29872241,-8.284512238,-9.152203392,-10.19598887,-4.908856009,-0.6473990820000001,-1448.0175894759595 -4493,4493,Y260L,-0.08491440300000001,-0.020775004,-0.031811312,-0.000948022,-0.046084325,-0.07697824,-0.03523412,-0.134594686,-0.015423212,-0.007878761,-0.033671246,-0.02169377,-0.041928852999999995,0.027425487999999998,-0.029321531,-0.016441901000000002,-0.07572674900000001,1.1219573870000001,2.500446185,-9.394937222000001,-6.149372252999999,-13.74204079,-8.5809543,-8.757868309,-9.744450455,-4.559047713,0.155257905,-1436.6138304378837 -4494,4494,Y260N,-0.05256500099999999,-0.368327012,-1.7676129230000002,-1.9237781000000003,-2.781605528,-0.003444473,-0.05452636,-0.050603642000000004,0.040031585,-0.050388432999999996,-0.686265591,-1.4638015180000001,-2.071424327,-1.509216909,-2.338339291,-2.502804252,-3.060406804,3.405671808,1.921040951,-12.15684767,-11.76765697,-14.97679545,-9.590075667999999,-12.25124696,-12.19846331,-8.659608795,-6.388198237,-1454.5399212371558 -4495,4495,Y260Q,-0.061500257999999995,-0.022123325,-0.687588545,-1.979071578,-2.9505208960000004,-0.036250582999999996,-0.07083524599999999,-0.05216526900000001,-0.058462377999999995,-0.027300959,-0.01694569,-0.325207542,-1.0499695470000001,-1.695134025,-2.26300913,-2.438843895,-3.462197897,1.528841336,0.78963823,-11.142638,-10.66141721,-13.7358939,-9.652681763,-11.50468201,-10.15851513,-6.252297467999999,-4.236982022,-1459.1971806110814 -4496,4496,Y260P,-0.058138034000000005,-1.562253741,-2.064005811,-2.484307877,-2.5155290480000003,0.009588218,-0.08367318900000001,-0.032602879,-0.110849944,-1.652062961,-1.47244452,-1.98888761,-2.139124011,-2.636362993,-2.332252761,-2.550769089,-2.480289006,-0.043995955,-1.069313228,-14.82202447,-13.40235117,-17.79424993,-12.69574359,-14.48232264,-15.73545503,-10.00794245,-9.205784818,-1440.0644991314039 -4497,4497,Y260S,-0.061731257000000005,-0.029667082,-0.371459414,-1.789700372,-2.7245762819999997,-0.073910141,-0.094557031,-0.028905483,-0.027906979,-0.001603376,-0.057730787,-0.10856678300000001,-0.634352045,-1.436871945,-2.142528799,-2.216579467,-3.232573097,1.36834592,0.816332658,-9.693370224,-9.086387611000001,-12.71046552,-6.902050911,-8.637379272,-11.130567800000001,-6.70220929,-4.858032158,-1441.9227228020318 -4498,4498,Y260R,-0.07792806599999999,-1.616122091,-2.223777567,-2.225838455,-2.746634556,-0.058082475999999994,-0.131275459,-0.024580672,-0.11328506699999999,-1.601567206,-1.630676976,-2.372047416,-2.075507717,-2.241371549,-2.21030536,-2.456807641,-3.03646147,-0.032484545,-1.047981936,-14.48581558,-14.71467525,-18.30357701,-12.74436176,-14.30432349,-12.36214037,-9.809122211,-8.256829066,-1444.6505012409762 -4499,4499,Y260T,-0.103093154,-0.054476467,-0.079361717,-1.051979135,-2.274308919,-0.014279584,-0.118310001,-0.08787630699999999,-0.040105668,-0.019997939,-0.088954995,-0.08071724200000001,-0.078006192,-0.5654653279999999,-1.538492942,-1.79514186,-2.753475977,1.8864402359999999,1.501916786,-10.92885226,-9.803135475,-13.51393238,-8.700574722,-10.40580414,-12.22081456,-6.795837818,-3.607504258,-1438.2474109800532 -4500,4500,Y260W,-0.038686043999999996,-0.047330685,-1.102839299,-2.14392802,-3.221421795,-0.059147698,-0.082652529,0.0052804409999999994,-0.07375445900000001,-0.048892185,-0.045769184000000004,-0.728596586,-1.477082011,-1.96200246,-2.325853579,-3.1316810619999997,-3.311162527,1.921668819,0.813342199,-10.09501888,-10.22924792,-12.01098456,-9.139470497000001,-9.063654968,-10.03173646,-8.290860154,-6.126662747,-1452.9444457930513 -4501,4501,Y260V,-0.122977346,-0.023628067000000003,-0.031510371,-0.02200698,-1.413474729,-0.031581751,-0.059360219000000006,-0.18659447199999998,-0.027461958999999998,-0.0015729079999999998,-0.045683225,-0.016797357,-0.046223385,0.000822253,-0.044836213,-1.034640295,-1.7923091619999998,0.821454006,1.368770616,-13.04895522,-11.49013168,-17.54958967,-10.59640195,-11.73966512,-13.86898766,-7.0313483429999994,-3.8355486880000003,-1432.7364191804081 -4502,4502,T261A,-0.014285978999999999,0.031585043,0.00022499,-0.007997066,-0.117114405,0.042901361,-0.035555301,0.006983343,0.054626727,0.014025895,0.049144191,0.066962824,-0.066512844,0.020116008,-0.036110139,-0.092204458,-0.142024352,1.133841839,2.235642028,-3.5120261060000004,-3.3514127730000003,-4.5638608860000005,-3.806197578,-2.26745713,-3.571202164,-4.494667495,-2.403969423,-1459.9594522188418 -4503,4503,T261C,0.003694396,-0.031294852000000005,-0.030040808999999998,0.00424798,-0.065010882,0.02695247,0.023088591000000002,-0.0156998,-0.015594038000000001,-0.046863387,-0.015726317,0.038421176,-0.098502793,0.033509274,-0.025013314,-0.031333519,-0.09868824400000001,1.350152086,2.616512074,-4.512133832,-3.2034690930000003,-5.500652733,-8.244894646,-0.421696716,-5.189955971,-3.790493301,-2.872153303,-1454.3304201164283 -4504,4504,T261E,0.039859412000000004,-0.059440648,-0.081492935,-0.157045469,-1.447797775,-0.191770437,0.07504148,0.004677344,-0.023980377,-0.060003654000000003,-0.058877640999999994,0.008482969,-0.171468838,-0.034370996,-0.279719942,-1.343887859,-1.5517076909999998,0.637290785,1.325152765,-7.557720436,-6.3646075589999995,-8.587375900000001,-8.518826386,-6.366083099,-7.951709236,-5.354834656,-4.721116578999999,-1451.6350128552876 -4505,4505,T261D,0.030741786,-0.155714523,-0.5066787389999999,-0.706035484,-1.133929996,0.01022771,0.023531156,0.037952415,0.370471304,0.232614481,-0.544043526,-0.180972252,-0.832385225,-0.287808527,-1.124262441,-0.6784852029999999,-1.5893747880000002,2.262126935,2.292978863,-9.533139777,-9.107868423,-11.84589209,-9.880145271,-7.193527199,-9.6382659,-6.443163018,-6.324624817999999,-1456.2454761480913 -4506,4506,T261G,-0.036664943,-0.001234837,-0.017182418999999997,-1.322676215,-2.325524065,-0.051397463,-0.025384518,-0.047945367,0.012822198,-0.012291503999999998,0.009821831,0.026859672,-0.06122451,-0.8843124370000001,-1.761039993,-2.07271327,-2.578334859,2.067978617,1.46461415,-7.12929641,-6.566768791,-7.364131767000001,-8.571052032,-5.342426453,-7.802103004,-5.6481758939999995,-4.187743361,-1451.3798156692646 -4507,4507,T261F,-0.044521289000000006,-0.012889473,-0.051048655,-0.037952887000000005,-0.069969718,-0.006021858000000001,-0.020356021000000002,-0.068686557,-0.011310625,-0.003476786,-0.02230216,0.004186028,-0.10628333699999999,0.018393444,-0.094299218,-0.023409322000000003,-0.116530114,1.181659282,2.445348648,-5.117860339,-5.613324997,-6.018670532000001,-6.735234833,-1.7859403459999998,-5.436130989,-3.6585157660000003,-2.368530593,-1449.4233835190535 -4508,4508,T261I,-0.030540215,2.34e-05,-0.038620157,0.008888233,0.027491917,0.088767939,-0.035476038,-0.025604391,0.051343085999999996,0.012744297,-0.012697487,-0.003989522,-0.073250791,0.026188633,-0.008412167,0.044644207000000005,0.010339626999999999,1.090621435,2.630263657,3.277041536,3.323406761,2.516452042,3.2474024810000004,5.873855392,1.424091003,-0.522038907,-1.292592916,-1467.384956145659 -4509,4509,T261H,-0.001769028,-0.003583015,-0.020217945,0.037207396000000004,-1.388134769,-0.063739223,0.015760414,-0.01929847,-0.03819257,0.008898598,-0.016064628,0.0029705440000000003,-0.043406433,0.09050342,-0.016088629,-1.347961745,-1.4283077919999998,0.784739269,1.3369278470000001,-6.864714277999999,-4.479100113,-8.002787735,-9.924378792,-5.260623466,-6.656681282,-4.443497762,-4.420776551,-1451.7034928207286 -4510,4510,T261K,-0.044051031,-0.032426187999999995,-0.113977936,-1.084118095,-1.583893884,-0.076007511,-0.0023738739999999998,-0.08572818800000001,0.101040294,-0.008761513,-0.056090862000000005,0.011139213,-0.239095085,-0.836648627,-1.331587563,-1.085852128,-2.081935639,3.686238482,3.283722507,-7.720299409,-7.072134308,-8.917007988,-8.709692733999999,-5.799580917,-8.1030811,-7.646808044,-9.277853798999999,-1456.0044780499302 -4511,4511,T261M,-0.020998582999999998,0.053144428,-0.022079583,0.010826222,0.039460117,-0.054975711,-0.010452412,-0.031544754,-0.040520272,0.072413817,0.033875037999999996,0.02842619,-0.07258535599999999,0.053755015,-0.032102571,0.06902793,0.009892303,1.151352105,2.927102096,2.532973883,2.722586792,1.146748825,2.858327263,5.294254417,0.642952118,-1.094487602,-3.198127944,-1466.9400694319047 -4512,4512,T261L,-0.031351776,-0.006616761,-0.044324127000000005,0.0028878959999999996,0.020071381,0.16211304599999998,-0.036644419,-0.026059132999999998,-0.015112181,-0.002413708,-0.010819813999999999,0.007891318000000001,-0.09653957099999999,0.019570545,-0.013794754,0.028627251,0.01151551,1.120269569,2.7206370910000004,3.645090091,3.570366051,2.10985791,4.08937088,6.755315979,1.700539635,0.046950566,-0.951933762,-1464.702664390672 -4513,4513,T261N,-0.036233932999999996,0.001601363,-0.038955767,-1.349785869,-2.063688368,-0.051540832,-0.0051095179999999995,-0.067358347,0.029436146,0.014159295,-0.01095657,-0.010365114,-0.06754642,-0.929337138,-1.7702345990000001,-1.67018104,-2.457195696,2.6554563190000002,2.012494189,-7.168128453,-6.639373268,-8.313595024,-8.935227074,-5.513446579,-6.43900032,-5.2021824930000005,-4.41433678,-1455.7112091053277 -4514,4514,T261Q,-0.026865226000000002,-0.00275608,-0.021137747999999998,0.006407391,-0.734585906,-0.014863336999999999,0.009702111999999999,-0.063432564,0.014772212,-0.031777404,0.026265245,0.021705917,-0.063981412,0.025387375,-0.012572594,-0.5103628729999999,-0.9588089390000001,1.1699289940000002,1.6263789419999999,-4.767972841000001,-4.741293152,-5.357062706000001,-5.36631485,-2.7241427380000003,-5.651050757999999,-5.142377456,-5.646783214,-1457.1432767696679 -4515,4515,T261P,-0.051729660999999996,-1.209048012,-1.4783914740000001,-1.705794403,-2.009491872,-0.071243059,-0.025604356,-0.077854965,-0.052075845,-1.0654965779999999,-1.352599445,-1.275320625,-1.6814623219999998,-1.4214102,-1.990178606,-1.537679359,-2.481304385,4.366353343,2.898416335,-8.584564052000001,-8.154872025,-9.921804855,-9.396705505,-6.840224373,-8.609213501000001,-7.646808044,-9.277853798999999,-1455.0372530617751 -4516,4516,T261S,-0.04153625,0.005249399,-0.027775817999999997,-0.012569236000000001,-0.152342955,-0.039757827,-0.055492547999999996,-0.027579951000000002,0.01807994,0.007255633,0.003243164,0.042052023,-0.09760365900000001,0.030696151,-0.055834623,-0.107695851,-0.196990058,1.43893518,2.435965157,-3.696815382,-2.004771515,-4.224057846,-5.828063255,-2.619714195,-3.8074701,-3.299103984,-0.549150281,-1455.44687184738 -4517,4517,T261R,-0.047435105,-0.0053314619999999995,-0.22735906399999997,-1.6601801669999998,-2.221617153,-0.061305822,-0.029643976000000002,-0.06522623400000001,0.038482868999999996,-0.002044636,-0.008618288,-0.037572142,-0.417145986,-1.340992737,-1.979367597,-1.772584238,-2.670650068,3.3144831060000004,2.457911933,-6.857941971,-8.071361259,-7.635661728,-7.1355267179999995,-5.219129875,-6.228030273,-6.381694369,-6.779492967,-1454.8269092808478 -4518,4518,T261W,-0.03827179,-0.021851206,-0.05495697,-1.328809776,-2.401692131,-0.06723920900000001,-0.0037301590000000003,-0.07281342,0.042824127000000003,-0.04573751,0.002035099,-0.036264641,-0.073649298,-0.964409084,-1.6932104669999999,-2.131942539,-2.671441722,2.083651164,1.438073243,-7.323701797000001,-5.9325257570000005,-9.593874298,-8.626766487000001,-5.153449615,-7.31189283,-5.176521596000001,-5.092067627,-1447.9103598608635 -4519,4519,T261V,0.004266720999999999,0.013900202,0.020052301,0.032847247,0.010115662,0.091204147,-0.005128185,0.013661626000000001,0.025662384,0.011315133,0.016485271,0.071308852,-0.03120425,0.052959044000000004,0.012735449,0.014852278,0.005379046,1.114724013,2.619711616,1.951414241,1.8126194080000002,1.7852749940000001,1.5795284580000002,4.105285858,0.47436248799999997,-1.656496313,-0.631351952,-1468.5258911219425 -4520,4520,T261Y,-0.054803606,0.016493944,0.018235118999999998,-0.371292389,-1.629958204,-0.07076115200000001,-0.001800183,-0.10780702800000001,0.048366282000000003,0.07044913400000001,-0.037461247,0.087809976,-0.051339739,0.018195138,-0.760779915,-1.337376576,-1.922539831,0.561859367,1.320689651,-6.528076045,-4.239351334,-9.035394753,-9.587568747999999,-3.151636696,-6.6264286960000005,-3.424101368,-2.205381852,-1442.6789906499907 -4521,4521,T262A,0.011848743,-0.024133379,0.012453365,-0.027588368,-0.18460336300000002,0.019847643,0.014933162,0.008764323000000001,-0.006035782,-0.004324182,-0.043942575,-0.037257789,0.062164519,-0.025105443999999998,-0.030071291,-0.165429824,-0.20377690199999998,1.2838167440000001,2.066464124,-4.149901099,-3.927634903,-4.961742622,-4.079368713,-4.302227959,-3.4785312960000003,-4.667009366,-1.24072319,-1454.9447774086148 -4522,4522,T262C,-0.020163147,-0.023859035,0.004085288,-0.049625657999999996,-0.499777363,-0.012773316000000002,-0.008002867,-0.032323426,-0.041023277000000004,0.000956118,-0.048674187,-0.022639137,0.030809713,-0.018919703,-0.080331613,-0.314724307,-0.684830418,1.3507753130000002,1.910469959,-9.45830834,-7.8044279020000005,-10.63278175,-8.962347694,-10.002203699999999,-9.889780655,-8.084541927,-4.201648578,-1447.782469260972 -4523,4523,T262E,0.00072749,-0.009113868,-0.005898191999999999,-0.032555413,-0.34293720899999997,0.015745521000000002,0.006154741,-0.004699762,0.074728013,0.010249704,-0.028477439,-0.099266564,0.087470181,-0.035297089,-0.029813737000000003,-0.319983559,-0.365890858,2.052106022,2.500303776,-9.382194424,-9.321837936,-10.24132143,-9.057890686,-8.871168465,-9.418753601,-4.865470376,-1.038974493,-1452.3786382954568 -4524,4524,T262D,0.016751967,-0.007382977,-0.004817269,-0.029182469,-1.492670549,-0.036967075,0.034264988999999996,-0.0007610560000000001,-0.043957962,-0.0016488429999999999,-0.013117111,-0.047268925,0.037634388,0.01860307,-0.076968008,-1.4653467580000001,-1.51999434,0.458796644,1.310537506,-8.83371104,-7.595291199,-10.97392264,-8.188586166,-8.172025635,-9.238729561,-6.502219107,-1.264493919,-1455.0679790363647 -4525,4525,T262G,-0.007282321,-0.014294871,-0.009217002,-0.128957456,-1.73144799,-0.008249249,0.001195197,-0.015759838999999998,-0.031805125,-0.006128565999999999,-0.022461176,-0.05013849099999999,0.031704487,-0.015356322,-0.242558589,-1.642255695,-1.820640284,0.444685786,1.304532869,-6.792878932000001,-8.333815956,-5.812388695,-7.99049337,-6.138011841,-5.689684799,-5.868810379,-2.2205034340000003,-1456.6879580626264 -4526,4526,T262F,0.022710498,-0.01090472,0.022961332,-0.014943008999999998,-0.92448673,0.005847722,0.043344693,0.002076302,-0.022259482,-0.002937333,-0.018872106,-0.042359425,0.08828208900000001,-0.040471131,0.010585113,-0.6894348509999999,-1.1595386079999999,0.97504803,1.47039466,-10.66048442,-9.713035187000001,-12.0591229,-10.3340136,-10.50092654,-10.69532387,-7.54727813,-4.48376697,-1435.3463823469356 -4527,4527,T262I,-0.017412538,-0.025216039,-0.046369305,-0.093185835,-0.328180078,-0.001555474,0.010087077,-0.044912152000000004,0.100168479,-0.014565015,-0.035867063,-0.145687012,0.052948403,-0.114529912,-0.07184175799999999,-0.346146936,-0.310213219,1.482670916,1.9343737490000001,-8.338454524,-7.365131081,-10.06267982,-7.511862595,-7.76326767,-8.989331451,-7.920299201000001,-4.088838486,-1433.590330796782 -4528,4528,T262H,0.014487176000000001,-0.016890748,0.0017189879999999999,-0.041867014,-0.056949167,-0.032519822000000004,0.01460496,0.014369392,-0.006481471999999999,-0.018671361,-0.015110133999999999,-0.054226783,0.057664757999999997,-0.041690111,-0.042043917,-0.06610042599999999,-0.047797907,1.417506744,2.441899588,-7.848566275,-6.100214401000001,-8.972610481,-7.381778137,-7.55733622,-9.230892136,-6.591762974,-2.413720546,-1458.728184883017 -4529,4529,T262K,0.007479156999999999,-0.046787775999999996,-0.0059101119999999995,-0.006335176,-0.288236162,0.063129212,0.00734704,0.007611274,0.034006173,-0.027156836,-0.066418715,-0.084971802,0.07315157900000001,0.007926739,-0.02059709,-0.32429408600000004,-0.252178238,1.461701836,1.98750196,-7.050550815,-6.584538322,-8.319453995,-6.808058456,-5.633666267000001,-7.907037033,-5.039956949,-0.631447024,-1453.6758752609603 -4530,4530,T262M,-0.0011178639999999999,-0.01789127,0.0069682319999999996,-0.014061376,-0.303880306,0.062160104,0.0061240190000000005,-0.008359746999999999,0.10288746300000001,0.010101623,-0.045884162,-0.026005626,0.03994209,0.008258169000000001,-0.036380921000000004,-0.20199746699999999,-0.40576314399999996,1.208418751,1.9610868609999998,-7.150220375,-6.119265091,-8.725239349,-7.257596596,-6.857623413,-6.791377426,-6.920505202,-2.8538905710000004,-1439.8205075925216 -4531,4531,T262L,-0.012137823999999998,-0.013693745,-0.001172104,-0.042542135,-1.271330923,0.058934492000000005,0.025744285,-0.050019932999999996,-0.019782714,0.004186877,-0.031574366,-0.041268683,0.038924476,-0.04246222400000001,-0.042622046,-1.038867991,-1.503793855,0.830296741,1.3695451769999998,-9.165628055,-7.42555542,-11.23355715,-8.785360374,-8.477951256,-9.905716072,-7.410045332999999,-3.994255027,-1436.560550717637 -4532,4532,T262N,-0.009044304,-0.027645316,-0.036746265,-0.07247181700000001,-0.25209262600000004,0.026403523999999998,-0.019764052,0.001675445,0.043912555,-0.038892363,-0.016398268,-0.08163875,0.008146221,-0.030784892,-0.114158742,-0.199402443,-0.304782809,1.661032361,2.346463409,-7.177688963,-6.340127289,-6.210756821,-6.88868119,-7.839890662999999,-8.608988853,-5.8279781879999994,-1.7044311840000002,-1463.7840529372916 -4533,4533,T262Q,0.01593764,-0.012038894,-0.022007389,-0.019957494,-0.12715858300000002,-0.003303514,0.052434839000000004,-0.020559558999999998,0.06829655,-0.000535552,-0.023542235,-0.082787172,0.038772395,-0.003830992,-0.036083995,-0.164170066,-0.09014709900000001,1.385678329,2.187890627,-8.625826591000001,-8.421038246,-8.844362381,-8.861117263999999,-7.961960228,-9.040654839,-6.700774634,-1.788018251,-1457.1562623041682 -4534,4534,T262P,-0.024020357000000003,-0.297829203,-1.51467981,-2.012471149,-2.535717236,0.035346496,0.013757778,-0.061798491,-0.031593282,-0.083797022,-0.511861383,-1.4391423509999999,-1.590217269,-1.947821214,-2.077121084,-2.375723948,-2.695710524,3.650370446,2.066779367,-11.35265139,-10.79673875,-12.04243652,-10.6154052,-11.85809808,-11.45057841,-9.766513152,-6.437760534,-1445.2098017577082 -4535,4535,T262S,0.031549021000000003,-0.011046225,0.0061523540000000005,-0.026530357999999997,-0.076728028,4.9e-05,0.049801628,0.013296414,-0.027476615,0.0027804229999999997,-0.024872872999999997,-0.046428747,0.058733455,-0.041845278,-0.011215437,-0.087966134,-0.065489922,1.4287967990000001,2.386921926,-4.853970601,-3.736562202,-3.9302580639999998,-4.7847204439999995,-5.905135735,-5.913176559,-4.072834797,-0.7119671129999999,-1464.5327468672767 -4536,4536,T262R,-0.002055447,-0.021307677,0.00906787,-0.039143154,-0.770570643,0.04611018099999999,0.018395276000000002,-0.022506169,-0.040772123,-0.006245214,-0.03637014,-0.050130398,0.068266138,-0.0311096,-0.047176708,-0.5579376389999999,-0.9832036470000001,1.014552155,1.5273885459999998,-6.536943355,-5.274847351,-7.103636848,-7.554369949,-5.930428307000001,-6.821434319,-4.450871755,-0.554171596,-1457.5823044120334 -4537,4537,T262W,-0.002091769,-0.022006907000000003,0.018885843,-0.026839077000000003,-0.543352313,0.052812230999999994,0.023180218,-0.027363756,-0.011496702,-0.010330231,-0.033683582000000004,-0.033749678,0.071521364,-0.032146571,-0.021531582,-0.365837275,-0.720867351,1.8295330580000002,2.244154105,-10.23424948,-9.047029854,-11.23502734,-9.491521812,-10.202839599999999,-11.1948288,-6.712109229,-3.7282675419999998,-1449.1689837323502 -4538,4538,T262V,0.004094788,-0.014804794,0.002196313,-0.040168926,-0.078381564,-0.021448175,-0.008229329,0.016418905,0.037269626,0.007274023,-0.03688361,-0.04080321,0.045195835999999996,-0.024370972999999997,-0.055966878,-0.060957609,-0.095805518,1.237246678,2.34953621,-6.610072385,-5.686063721,-8.810518425,-5.867086395,-6.030935989,-6.655757392999999,-6.452765512999999,-3.0905689510000003,-1437.0447781472467 -4539,4539,T262Y,0.04205206400000001,0.005950653,0.005186751,-0.029583539,-0.18513876399999998,-0.045929654,0.0280406,0.056063528,-0.046632902999999996,-0.005201194,0.0171025,-0.057595945999999995,0.067969448,-0.041006593,-0.018160485,-0.158060254,-0.212217273,1.466024791,2.187192313,-10.03465033,-8.536677582000001,-11.273066,-9.232341331,-10.070469699999999,-11.06069702,-7.125847021,-3.556608807,-1446.9611525204964 -4540,4540,G263A,-0.028484372999999997,-0.009941599,-0.03760421,-0.020299826,-0.974024595,0.167584776,-0.043938427,-0.013030318,0.043044517000000004,-0.0032855109999999996,-0.016597687,-0.016808879,-0.058399541,-0.014968249,-0.025631402999999997,-0.789211158,-1.158838032,0.7361847340000001,1.3864334669999998,-4.209983147,-4.137628609,-5.080710732,-2.736112312,-3.489566475,-5.605897606,-3.790887984,-1.127860543,-1454.66421559453 -4541,4541,G263C,-0.09720748,-0.007663335,-0.040404932000000005,0.000712993,-1.002343849,0.178624248,-0.10690145699999999,-0.087513503,0.06847394,0.044535054000000004,-0.059861723,0.005176643,-0.08598650699999999,0.03210325,-0.030677265,-0.76794235,-1.236745348,0.455173506,1.352391266,-8.766781047,-8.119428711,-9.239565605,-8.50408535,-8.4178078,-9.553017769,-6.22969773,-4.825425468,-1449.4191682888195 -4542,4542,G263E,-0.049265962,0.0028789420000000002,-0.033242707999999996,0.007960835999999999,-0.511025386,-0.017357618999999998,-0.035118434,-0.063413489,0.091604503,-0.002302086,0.008059969,-0.003931559,-0.062553857,0.033056363,-0.017134691,-0.36989251799999995,-0.652158253,1.763906751,2.207113698,0.39773747600000003,0.318015404,0.22959050000000003,0.168523697,0.7928812479999999,0.47967652899999996,-1.425394296,-0.876365216,-1461.5368954320438 -4543,4543,G263D,-0.020420396,-0.007605785,-0.022483863,-0.017287217,-0.225119598,-0.010112809,-0.038503139,-0.002337652,0.014340176000000001,0.008820762,-0.024032332000000003,-0.01114213,-0.033825595,0.003138529,-0.037712962999999995,-0.174608906,-0.27563029,1.31493548,2.079034833,-0.666998534,-0.8245933000000001,-0.278123787,-1.3711585309999998,-0.12049439199999999,-0.7406226579999999,-1.961873061,-0.289909593,-1459.0787818906829 -4544,4544,G263F,-0.034010893,0.012810676000000002,-0.03338027,-0.310949111,-1.960090392,0.038793158,-0.037540463999999996,-0.030481321000000002,0.021625596,0.035135496,-0.009514144,-0.02190677,-0.04485377,-0.037441296,-0.584456926,-1.895854692,-2.024326091,0.780512767,1.304420302,-10.43263229,-8.653844391,-10.09994276,-9.478297264,-12.10291817,-11.82815884,-5.882785527,-4.213475428,-1452.9487266759388 -4545,4545,G263I,-0.084415327,-0.015492916,-0.09630143199999999,-1.4048722390000001,-2.225456764,0.159107511,-0.121182521,-0.047648132999999995,0.11045258599999999,-0.028735704,-0.002250127,-0.021461757999999997,-0.17114110600000002,-0.852437983,-1.957306495,-1.997621927,-2.453291601,2.058817333,1.485659766,-8.503029451,-9.624964592000001,-10.63015932,-4.759716903999999,-8.813308188999999,-8.686998252999999,-5.0304128530000005,-3.764095653,-1449.3355774949305 -4546,4546,G263H,-0.0036760490000000002,0.002963259,-0.05831865,-0.020381756,-1.588938653,-0.032093197000000004,0.002237209,-0.009589307,0.057746236,-0.006766543000000001,0.01269306,-0.071361794,-0.045275505,0.021275907,-0.062039418,-1.46579636,-1.712080945,0.675564488,1.321332518,-5.087114111,-3.4460756839999998,-4.3785207669999995,-7.17128569,-5.7445558089999995,-4.695132607,-4.77117466,-2.152634703,-1456.397812523879 -4547,4547,G263K,-0.10162317900000001,0.011394885,-0.03864455,-0.22505367199999998,-2.214016011,0.038549788,-0.114286995,-0.08895936199999999,0.068048738,0.045046949,-0.022257179,0.02070558,-0.09799468,0.049669554000000005,-0.49977689799999997,-1.579069755,-2.8489622669999997,0.719369325,1.317873495,-3.900828882,-4.2940435180000005,-2.230540115,-5.191002502,-4.113692352,-3.6748659210000003,-4.251569175,-0.9772492840000001,-1452.8116608136334 -4548,4548,G263M,-0.010839136000000001,-0.011102727,-0.029771907,-0.00480984,-0.8520626170000001,0.13905444,0.002441457,-0.024119729,-0.016322493,-0.022860875,0.000655422,-0.026517463999999998,-0.033026348999999997,-0.0067588330000000005,-0.002860846,-0.719471848,-0.984653386,0.713026623,1.3941104380000002,-7.920160537999999,-8.531454437,-9.364031822000001,-5.402266441,-8.064323616,-8.238726372,-4.858404665,-3.581141265,-1455.199930199422 -4549,4549,G263L,-0.03898103,-0.007329136,-0.031712066000000004,0.008488045999999999,-1.341277354,0.040537604,-0.042065955,-0.035896104,0.135573327,-0.022400211,0.007741939000000001,-0.029132635,-0.034291496,0.031334506,-0.014358414,-1.043342157,-1.639212551,0.725923805,1.354505673,-7.5211431,-8.040713402,-9.767653037999999,-4.7001082080000005,-7.106046538999999,-7.991194312999999,-5.033801711000001,-3.3687566319999998,-1452.1672589168884 -4550,4550,G263N,-0.019561347,-0.023802695,-0.042058324,-0.045793843,-0.200660416,0.054905657999999996,-0.048194485999999995,0.009071792,0.072664025,0.008325036,-0.055930426,0.010526655,-0.094643302,-0.023570621,-0.068017065,-0.122744207,-0.278576624,1.330674272,2.241012084,-2.263897566,-2.020483727,-1.6860614619999998,-4.323045563,-0.8376687159999999,-2.452228363,-2.431608272,-0.631879314,-1458.4065458332188 -4551,4551,G263Q,-0.026182039,0.017507363999999997,-0.043068962999999995,-0.013681903,-0.622310764,0.058323691,-0.022008872000000002,-0.030355205,0.10121193,0.006632511,0.028382216000000002,-0.028713229,-0.057424697000000004,-0.00215089,-0.025212916000000002,-0.481254046,-0.763367482,1.049610639,1.586039056,-0.564383199,-0.537182617,0.05445731400000001,-1.4821103359999999,-0.373515274,-0.483565079,-1.6842511059999998,-0.9249558609999999,-1470.0101752895862 -4552,4552,G263P,-0.00459036,0.005873155,-0.004649849,-0.551592643,-1.844063311,0.450544561,-0.010751443999999999,0.001570724,0.114019707,-0.018682509,0.030428818,-0.017861795,0.008562098,-0.276522463,-0.8266628229999999,-1.929750122,-1.7583764990000001,1.363374546,1.3467124719999999,-8.157052945,-8.992086411,-9.286438858,-7.435432564,-6.3620350189999995,-8.709271872999999,-5.4869853189999995,-2.82238441,-1449.348245154135 -4553,4553,G263S,-0.006300363000000001,0.026546155,-0.009453026,0.014407683999999999,-0.875088118,0.105867572,-0.023876408999999998,0.011275683,0.057746236,0.040528029,0.012564281000000002,0.033015748,-0.051921799000000005,0.025559109,0.0032562579999999997,-0.669822755,-1.080353481,0.7707009840000001,1.415085614,-5.800674097000001,-6.098882088,-5.922126777999999,-6.3729871220000005,-4.443068314,-6.166306183,-4.156345555,-0.804264173,-1455.9636357179843 -4554,4554,G263R,-0.040506006000000004,-0.014057732,-0.031095533999999998,-0.013480012,-1.505519016,0.15935105800000002,-0.028646205,-0.052365805999999994,0.065087235,0.0045617470000000005,-0.03267721,0.0019072689999999998,-0.06409833599999999,0.036820093,-0.063780116,-1.4299754740000001,-1.5810625580000002,0.813330112,1.338763016,-3.9433476639999996,-4.418225533,-2.797971504,-4.97258654,-3.7519231410000002,-3.776031601,-3.896879717,-0.267572877,-1460.375333248172 -4555,4555,G263T,-0.055047609000000004,-0.01787746,-0.048022982,-0.00601571,-1.7170409640000002,0.18831633899999997,-0.044851112,-0.065244106,0.100637604,0.028962216000000002,-0.064717136,0.002765858,-0.098811821,0.07674677,-0.08877818900000001,-1.5565808209999998,-1.877501106,0.6495812870000001,1.315842272,-6.714000049,-6.89831282,-6.979839302,-6.074209023,-5.763407745,-7.8542313539999995,-4.15439875,-1.783626105,-1450.3395153935999 -4556,4556,G263W,-0.020392319,0.001424568,-0.010465341999999999,-0.652301284,-1.774132716,0.066486238,-0.008482811,-0.032301826,0.09730924699999999,0.004992836,-0.0021436999999999997,-0.040005888999999996,0.019075206,-0.23878879100000003,-1.065813776,-1.71438442,-1.833881012,1.284154901,1.3615696380000002,-9.306830794,-8.553217827000001,-8.801072502,-9.147896507,-10.83714317,-9.194823958999999,-6.250116515,-4.684196807,-1452.951794677414 -4557,4557,G263V,-0.035607663,0.017062146,-0.023432272999999997,-1.004819675,-2.019069464,0.238626232,-0.010877864,-0.060337460999999995,0.048494993,0.02872837,0.005395921999999999,-0.025896241,-0.020968305,-0.622222598,-1.387416751,-1.9213351109999999,-2.116803817,1.5104011119999998,1.354256014,-8.244447395,-9.137481361,-10.09663457,-5.128026596000001,-8.190919762,-8.66917469,-5.210399462,-3.682303366,-1451.7260702960193 -4558,4558,G263Y,-0.100701284,-0.031957268,-0.04519089,-0.40684249100000003,-1.9925296069999998,0.063608752,-0.066167832,-0.135234736,0.125769344,0.012054236000000001,-0.075968772,-0.027206986000000002,-0.063174794,-0.110706894,-0.702978088,-2.098822817,-1.8862363969999998,0.697101523,1.288680203,-9.753437599,-7.218355422999999,-9.197708237,-10.58242555,-11.93368011,-9.835018677,-5.953697702,-2.977096242,-1447.9200834305957 -4559,4559,S264A,0.014030355,0.00313289,-0.00468941,0.010981056999999999,-0.157365839,0.10126218699999999,-0.001750086,0.029810795,-0.039510244,0.007421411,-0.001155631,-0.00522176,-0.00415706,0.030654819,-0.008692706,-0.12782692,-0.186904757,1.5016806790000001,2.468476538,-2.875053424,-3.8807894210000002,-4.232066078,-1.700779808,-2.874291908,-1.687339905,-3.778166047,-0.444092331,-1457.8915182873607 -4560,4560,S264C,-0.061231732000000004,-0.020652297,0.007938299999999999,0.0031190040000000003,-0.83391204,0.197245261,-0.06488383,-0.057579634000000005,-0.11127163,-0.000793787,-0.040510806,0.021834764,-0.005958165,0.03090135,-0.024663342999999997,-0.43319563200000005,-1.234628448,0.7861573690000001,1.4981573680000002,-5.262163591,-4.658764473,-6.789347,-4.713685371,-5.934115723,-4.214905388,-3.950054783,-3.086343411,-1456.6192335579544 -4561,4561,S264E,0.009047231,-0.006651471,-0.055327865999999996,-0.9745319570000001,-1.884315762,0.052465719,0.015055822,0.003038639,-0.058479227,-0.014600829,0.001297887,-0.078377858,-0.032277874,-0.511470599,-1.4375933140000001,-1.515706286,-2.252925238,2.082525151,1.706585842,-6.417645518,-8.415867989,-7.417650856,-6.1179005360000005,-5.406112679,-4.730695534,-4.148774767,-2.0886645269999997,-1452.0557787539437 -4562,4562,S264D,0.018067423,-0.026824037999999998,-0.043720325,-1.065546375,-1.703690832,-0.01962617,-0.010836018000000001,0.046970863,-0.052916713,-0.005694905,-0.047953170999999996,-0.07289923599999999,-0.014541413000000001,-0.7916934109999999,-1.339399339,-1.7595766369999999,-1.647805026,2.284575869,1.6990666630000002,-5.4977071429999995,-7.437304512000001,-5.83582177,-4.96013649,-5.48496936,-3.7703035810000003,-3.58429166,-0.861598106,-1453.165389106609 -4563,4563,S264G,0.007237908,0.011051018999999999,0.0005777719999999999,0.008649558,-0.061236874000000004,0.041796952000000005,-0.029260192999999997,0.043736008,-0.025330894,0.010216558,0.011885479,0.009074208,-0.007918665,0.041385054,-0.024085937999999998,-0.048978782,-0.073494965,1.2637275270000001,2.475357208,-5.452456357999999,-7.732986282000001,-6.3772957,-3.0032255780000003,-6.449733459,-3.6990407710000004,-2.929052827,-0.97637439,-1451.5461135799997 -4564,4564,S264F,-0.047248112,0.006769254000000001,-0.05140238900000001,-1.000720125,-2.164877315,0.055535945999999996,-0.016649745,-0.07784647900000001,0.013667106000000002,0.037400125,-0.023861617999999998,-0.073724446,-0.029080332,-0.398822742,-1.602617508,-1.732769559,-2.5969850709999998,1.2685669259999999,1.353155061,-7.722145206,-8.456375228999999,-8.103623024,-7.760581276,-7.1699593120000005,-7.120187187000001,-4.707118941,-1.9393215990000001,-1450.9335673679598 -4565,4565,S264I,-0.033589587000000004,-0.012891226,-0.02702467,-0.7222777840000001,-2.1641448569999997,0.075654895,-0.030953252999999997,-0.03622592,0.030057522000000003,-0.043866128,0.018083676,-0.105514847,0.051465507,-0.23560931300000001,-1.208946254,-1.72422794,-2.6040617740000003,1.3628674230000002,1.3744913680000002,-7.109113107000001,-8.258719879,-7.161000496000001,-6.7060257420000005,-8.298201195,-5.121618225,-5.128976596,-1.541540724,-1458.8554761172272 -4566,4566,S264H,-0.008587872,-0.006339224,-0.046946083,-0.214581068,-1.974231479,0.040956652999999996,-0.025746982999999998,0.00857124,0.030057522000000003,0.00697195,-0.019650398,-0.093980566,8.840000000000001e-05,-0.0060111159999999995,-0.42315101899999996,-1.779610079,-2.168852879,0.714015707,1.307921458,-5.922316867,-8.265671783,-7.062484726,-5.902382957,-5.209924622,-3.1711202469999997,-4.930202457,-2.178370395,-1452.8096903921105 -4567,4567,S264K,-0.039657526,-0.034307361,-0.073494226,-0.168587018,-1.853998581,0.155476683,-0.037307169,-0.042007882999999996,0.04908076,-0.0010015339999999999,-0.067613187,-0.067089024,-0.079899428,0.043843447,-0.381017482,-1.468955435,-2.239041726,0.597885699,1.316738267,-5.056724313,-6.968138382,-5.191095184,-4.399631905,-5.127989655,-3.596766441,-4.021337011,-2.464426465,-1452.0387191218324 -4568,4568,S264M,0.023053182999999998,-0.045848402999999996,-0.069584432,-0.007477978000000001,-1.52296629,0.061818995999999994,0.029275281,0.016831085,-0.073075855,-0.080248279,-0.011448526,-0.13363458,-0.005534283,0.031797778,-0.046753733,-1.443318378,-1.6026142019999998,0.5722636489999999,1.316109343,-7.922894038,-9.076979454,-7.029837952,-8.045745644,-8.39584037,-7.066066772,-5.492778447,-2.925700202,-1460.9930160497315 -4569,4569,S264L,-0.041432687,-0.030345465,-0.020574312,-1.047610989,-2.185465744,0.037060113,-0.031695747,-0.051169627,0.018358647,-0.005608401,-0.055082528,-0.023675761,-0.017472863,-0.46325130200000003,-1.631970675,-1.9811194380000001,-2.38981205,1.595624795,1.372003958,-7.826166499,-9.651219727,-7.781398727000001,-8.754852638,-7.990710289,-4.952651115,-4.331150296000001,-0.9544664820000001,-1456.2419224753976 -4570,4570,S264N,-0.046606409,-0.010337215,-0.055456806,0.023379266,-1.146017061,0.08877749199999999,-0.068721582,-0.024491236,-0.114434751,0.00534499,-0.026019419,-0.059124486,-0.051789125,0.079454035,-0.032695503,-0.7150734670000001,-1.576960654,0.541930145,1.365331674,-0.322673293,-1.2783722690000001,-0.5346699979999999,0.054650536,0.062300659,0.082724609,-1.8315957790000001,-1.1577307559999999,-1460.7610114393756 -4571,4571,S264Q,-0.017732408999999998,0.006009731,-0.030076212,-0.032417856,-1.79312276,0.124951235,-0.020531708,-0.014933108999999998,-0.040032546,0.023418415,-0.011398953,-0.038867097,-0.021285327000000003,0.046852972,-0.11168868400000001,-1.890589522,-1.695655998,0.586879577,1.299008959,-6.608459448,-9.616764198,-6.672174316,-6.946134224,-5.603032211,-4.204192291,-4.46778332,-1.6794296130000002,-1453.1013262989 -4572,4572,S264P,-0.034996624,-0.040449641,-0.110291679,-1.5169768069999998,-2.326807229,0.123103992,-0.021715626000000002,-0.048277621,0.057076365,-0.042554357,-0.038344924,-0.08117772,-0.139405637,-1.155309702,-1.8786439119999998,-2.021352885,-2.632261573,2.542090258,1.726625805,-6.001946898,-6.542418121,-5.977127997999999,-4.797720665,-7.061855209,-5.630612495,-3.124230551,-0.40762467,-1452.0146183385514 -4573,4573,S264R,-0.033303892,-0.002158925,-0.01905306,-0.37248958600000004,-1.654599757,0.24496117399999998,-0.032306874,-0.03430091,-0.011666812,0.009141283,-0.013459132,-0.01837351,-0.01973261,-0.038957162999999996,-0.706022009,-1.482227449,-1.826972064,0.669185008,1.319673223,-7.542838615,-10.02817562,-10.15477362,-6.442379288,-7.071416367,-4.017448181000001,-4.117887259,-1.50347734,-1450.272316655144 -4574,4574,S264T,-0.00930879,-0.025102462000000002,-0.029694652999999998,0.005860733000000001,-0.031791011,0.00356107,-0.025066334,0.006448755,0.072809503,-0.04432208,-0.005882844,-0.061890586,0.002501281,0.023128661000000002,-0.011407195,-0.037601047,-0.025980974,1.346499602,2.330677863,0.6832391170000001,0.7719685209999999,0.7824042659999999,0.713986382,0.23606063800000002,0.91177578,-0.800783747,-0.333621792,-1465.9701333697885 -4575,4575,S264W,-0.03701137,-0.036335358,-0.040632846,-1.247204822,-2.23411749,0.048382807,-0.020247011999999998,-0.053775727,-0.010028430999999999,-0.044897094000000005,-0.027773622,-0.052056143,-0.029209548,-0.7875832770000001,-1.706826367,-1.9535261769999999,-2.514708802,2.034163654,1.49591539,-9.473682346,-10.28819713,-10.10367625,-8.30988456,-9.432535858,-9.234117928,-5.572706863,-3.226737777,-1453.3653497253545 -4576,4576,S264V,-0.050420781,-0.020685394,-0.017367231,-0.299916642,-1.8695541480000002,0.064164998,-0.04680721400000001,-0.054034347999999996,-0.052773279000000006,0.001802319,-0.043173105999999996,-0.021708752999999997,-0.013025709,-0.019476246000000003,-0.5803570379999999,-1.6244296169999999,-2.114678679,0.78747563,1.319902724,-5.563815404,-6.643668869,-6.443362473,-4.921221222,-6.090290092,-3.720534363,-4.004210165,-1.308830387,-1458.4419573466294 -4577,4577,S264Y,-0.060755017,-0.050137142,-0.023876903999999997,-1.0606901709999998,-2.3589679969999997,0.06166054,-0.050158299,-0.071351735,0.061946667000000004,-0.005199179,-0.09507510400000001,-0.0032937009999999996,-0.044460106,-0.39884257799999995,-1.7225377640000001,-1.6961056280000002,-3.021830366,1.634918919,1.443603763,-7.871698178,-9.174095192000001,-8.485197533,-7.22027623,-7.01420842,-7.464713516000001,-4.738063775,-2.986202946,-1448.6722404924221 -4578,4578,Q265A,0.042492765,0.016703217,-0.002868155,-0.019031266,0.007296149,-0.014248718999999998,0.024572262,0.060413268,0.012031506,-0.010741734,0.044148168,-0.002731134,-0.003005175,-0.026598755,-0.011463777,-0.003314102,0.017906400000000003,1.3428298580000002,2.71359507,-1.129456656,-1.251494225,-0.42283254200000003,-0.18342443100000003,-2.214410004,-1.5751220780000001,-2.311807489,0.593920614,-1463.037839133758 -4579,4579,Q265C,0.015635141,0.012609201,-0.020334917,-0.038009941,-0.045596657,0.052913892000000004,0.014886568999999999,0.016383711999999998,-0.027470312,0.00121696,0.024001441000000002,-0.001143472,-0.039526361,-0.031116185,-0.044903697,-0.0236488,-0.067544513,1.307121673,2.5635055980000003,-6.134131061000001,-6.7742260739999995,-6.044303597000001,-5.361483208,-7.08680056,-5.4038418660000005,-6.773408159,-4.7671361789999995,-1460.8694677953608 -4580,4580,Q265E,0.08193562900000001,-0.002519987,-0.02770598,-0.018491827,0.02715064,-0.036268159,0.06425998,0.099611277,0.004952186,-0.026515012999999997,0.02147504,-0.037661528,-0.017750431,-0.05391181900000001,0.016928165,0.004552804000000001,0.049748475,1.226168769,2.5823727919999997,0.437351463,0.344221741,0.348820671,1.244198463,0.158474792,0.091041649,-2.053026874,0.7069593059999999,-1467.0169962877408 -4581,4581,Q265D,0.020641448,0.063860532,0.018170383999999998,-0.028453658,0.018464877,-0.011419163999999999,0.010613512,0.030669383999999997,-0.058423798,0.072015577,0.055705487000000005,0.059575120999999995,-0.023234354,0.039229638,-0.09613695300000001,0.074702899,-0.037773146,0.850566594,2.7485039689999997,0.22936678600000002,-0.11594793699999999,0.315224503,1.4300998,0.09733943199999999,-0.579881866,-1.116198971,0.647873967,-1463.9914831495844 -4582,4582,Q265G,0.040053063,0.01710046,-0.006608361,-0.031994063999999996,0.021784772999999997,-0.025236466000000003,0.019856672,0.060249453,0.007423393,-0.010085965,0.044286884000000006,-0.009594656,-0.0036220659999999997,-0.031167682000000002,-0.032820446,0.019872636000000003,0.02369691,1.204277377,2.578432526,-1.86489353,-2.130836327,-1.1560665970000001,-0.55668821,-1.970527275,-3.5103492430000003,-2.9377711019999997,0.04205366,-1460.6896622134373 -4583,4583,Q265F,-0.022871247,-0.03495527,-0.029046292999999997,-0.090125515,-0.072124116,0.051579800999999995,0.013891222,-0.059633715999999996,0.075610763,-0.055334234,-0.014576306,-0.052014193,-0.0060783930000000005,-0.08617291,-0.09407812,-0.055704777999999996,-0.08854345400000001,1.279019596,2.339457639,-6.134996567999999,-7.879184013,-5.207175606,-4.509172096,-6.066465126000001,-7.012986,-5.200715709,-1.584151303,-1455.9274431285448 -4584,4584,Q265I,0.080185498,0.035607078,-0.000988701,0.005143107,0.013407068000000001,-0.085509895,0.100398609,0.059972385999999996,0.026559745,0.023815904,0.047398250999999995,0.004361564,-0.006338966,-0.024131438999999998,0.034417653,0.022708427000000003,0.004105708,1.136173339,2.5670765490000003,-5.068337535,-5.870093987000001,-4.451726433,-3.931287582,-4.430952339,-6.657627335,-4.471046367,-2.183539496,-1462.2265199148096 -4585,4585,Q265H,0.045765925,-0.017652906,-0.001297824,-0.025484391000000002,-0.011547412,-0.017816485,0.033014042,0.058517808,0.010030312,-0.035788245,0.000482434,-0.004678449,0.002082802,-0.044078275,-0.006890507,-0.0028840240000000002,-0.0202108,1.2296809659999999,2.557797511,-1.8454045559999999,-2.508680115,-1.968893433,-1.4454149630000002,-1.920941002,-1.383093269,-2.180157505,-0.690860385,-1453.3703556526452 -4586,4586,Q265K,0.010971079,-0.031122139,-0.01571936,-0.024909355,0.031578232000000005,-0.014083993000000001,0.022342211,-0.00040005300000000004,-0.022185543,-0.028182328,-0.034061949,-0.036885,0.00544628,-0.037527111,-0.012291598999999999,0.034160832,0.028995632,1.151166808,2.571170035,0.080061525,0.480068321,-0.002937141,0.744700615,-0.270477417,-0.551046753,-1.629402059,0.806842299,-1461.3364377631806 -4587,4587,Q265M,0.02582843,-0.020914929,-0.029816699,-0.02550843,0.012483781999999999,-0.017426228999999998,0.020487003,0.031169857000000002,-0.022616796,-0.015085551,-0.026744306000000002,-0.013464323,-0.046169075,-0.004050728,-0.046966130999999994,0.00538879,0.019578774,1.177100104,2.659550514,-4.756326613,-5.212896141,-5.035090607,-3.9860657880000003,-4.619007965,-4.928572563,-4.499075856,-1.692107595,-1460.9745496809483 -4588,4588,Q265L,0.035553355,0.020213109,0.0090118,-0.007238046999999999,0.009050001,-0.006434513,0.05102574,0.020080969,0.029917935,0.000399528,0.04002669,0.002464594,0.015559006,-0.013051078,-0.001425015,0.014565121,0.00353488,1.165991797,2.640183532,-4.5522723019999995,-5.704207877999999,-5.106309517,-3.3507104639999996,-3.331065086,-5.269068565,-4.201444347,-1.014486933,-1458.769711179193 -4589,4589,Q265N,0.035372497,0.009299083,-0.035646392,0.002078983,0.057900198,-0.03121396,-0.014231925,0.08497691800000001,0.07029761799999999,-0.025783485,0.044381650999999994,-0.019869038999999998,-0.051423744,-0.009376849,0.013534814,0.021476562,0.09432383400000001,1.4418159069999998,2.7830227260000004,-1.079458675,-1.4961757580000001,-0.698349777,-0.71786219,-0.8815245740000001,-1.6033810730000002,-2.922086161,-0.412021855,-1462.176666868385 -4590,4590,Q265P,0.033479285,0.014454858000000001,0.000129577,-0.020894173000000002,-0.002765732,-0.029154499,0.016946423000000002,0.050012147,0.008520324000000001,-0.004877412,0.033787127,0.0023975389999999997,-0.002138386,-0.026811322000000002,-0.014977023999999999,0.002547557,-0.008079021,1.26423606,2.658294344,-0.999888963,-0.130305054,-0.652441811,-0.057754715,-2.016401833,-2.142541405,-1.342867274,0.267389005,-1451.4777369061485 -4591,4591,Q265S,0.032842689,-0.003225752,-0.020299962,-0.035852091,0.025386272,-0.025072192000000004,0.011754074,0.053931304000000006,0.003176281,-0.024987371,0.018535867,-0.018954552,-0.021645372000000003,-0.028632496,-0.043071686,0.011617872,0.039154671,1.20546845,2.53240831,-0.8557982479999999,-0.997512947,-0.419145889,-0.43603694200000004,-1.684705551,-0.741589912,-1.650033429,0.42440759100000003,-1458.5141485417262 -4592,4592,Q265R,0.025854331,0.015738455,-0.01280294,-0.030861200000000002,0.011668405,-0.00463903,0.04020749,0.011501171000000001,0.003813734,-0.03355897,0.065035879,-0.019924399,-0.00568148,-0.045407092999999996,-0.016315307,-0.008409514,0.031746323,1.279762208,2.5935537369999997,-1.053425443,-1.591141479,-1.532817093,-0.444491821,-1.576588264,-0.122088554,-2.505593958,0.508513684,-1454.6780972024426 -4593,4593,Q265T,0.038330228,0.01880192,-0.0019082460000000002,-0.04940008,0.016477116,0.000456617,0.023889612,0.052770844000000004,0.025697313,-0.021200449,0.058804289,0.0067052990000000005,-0.01052179,-0.045376997,-0.053423162,0.013202536,0.019751695,1.308775547,2.591379482,-0.172983107,-0.046226387,0.533442772,0.508756027,-1.696491501,-0.164396446,-1.944324161,0.92285851,-1461.6957267322578 -4594,4594,Q265W,0.048525862,0.028786002,-0.013611858999999999,-4.59e-05,-0.033193385,-0.027001742000000002,0.034624267,0.062427456,0.050752980999999996,-0.002604965,0.060176969000000004,0.006136295,-0.033360013,0.0011382410000000001,-0.0012300030000000001,-0.040141500000000004,-0.02624527,1.34675048,2.55281712,-5.824503432,-6.590552513,-5.337723747,-4.26220787,-5.549509895,-7.382523132,-5.481224246,-2.605343291,-1460.849159764126 -4595,4595,Q265V,0.004879323,-0.014099698,-0.048829454,-0.012788863999999999,-0.015321831999999999,-0.045433935999999994,-0.008662755,0.018421401,0.012494983999999999,-0.011635092,-0.016564304,-0.043106267000000004,-0.054552641,0.005887526999999999,-0.031465255,0.007340592,-0.037984255,1.222735381,2.6658805709999998,-3.29796792,-3.975531593,-2.5182025219999997,-1.8681586380000001,-3.163455917,-4.964490929,-3.772100333,-0.428144896,-1463.3939554705285 -4596,4596,Q265Y,0.119990645,0.071117446,0.006734652,0.02416805,0.036114718,-0.006760913,0.111442961,0.128538328,-0.004378883,0.003970088,0.138264804,-0.019849308,0.033318611,-0.0048204829999999995,0.053156583,-0.004563354,0.076792789,1.180671504,2.553011113,-4.794675983,-6.086442947,-4.037893433,-3.526507057,-4.862276871000001,-5.460259605,-4.971919866,-1.209698856,-1451.9149156874046 -4597,4597,A266C,0.518992387,-0.016049777,0.031559422999999996,0.043112156,0.001832707,,0.518992387,,0.028396723999999998,-0.016049777,,0.031559422999999996,,0.043112156,,0.001832707,,1.203283939,2.544351378,-9.611312599,-10.46384925,-9.678318954,-10.77058944,-8.699876961000001,-8.443928391,-7.485041592000001,-5.6720472079999995,-1454.4389400426298 -4598,4598,A266E,-0.048413773,-0.019240548,-0.015483557,0.030011612000000003,0.035025403,,-0.048413773,,0.026226022999999998,-0.019240548,,-0.015483557,,0.030011612000000003,,0.035025403,,1.1075174509999999,2.634571048,-7.519382848999999,-9.149027359,-6.131167389,-8.497146118,-6.732920784,-7.086652596,-5.072615722,-0.538610415,-1460.1983882244676 -4599,4599,A266D,0.19884235100000003,-0.012641397,-0.032308955,4.07e-05,-0.064810058,,0.19884235100000003,,0.029611426,-0.012641397,,-0.032308955,,4.07e-05,,-0.064810058,,1.4758646819999999,2.5448878230000003,-9.38283797,-11.84464311,-8.755695053,-10.53382947,-7.9186575779999995,-7.861364639,-4.86006911,-0.816376268,-1457.3464613123797 -4600,4600,A266G,0.061345422000000004,-0.024056809,-0.039491087,-0.000816358,-0.009499068000000001,,0.061345422000000004,,-0.009162203,-0.024056809,,-0.039491087,,-0.000816358,,-0.009499068000000001,,1.671448915,3.643209181,-7.140749799,-8.363322487000001,-6.848897002999999,-7.263406754,-5.382646675,-7.845476074,-5.035819876000001,-1.6826594330000002,-1455.369705399964 -4601,4601,A266F,0.29728185,-0.0037698740000000003,-0.136154465,0.007059595,-0.0305753,,0.29728185,,0.076606455,-0.0037698740000000003,,-0.136154465,,0.007059595,,-0.0305753,,1.323380862,2.587888183,-11.68021708,-12.26620926,-11.31065618,-14.78654055,-11.69767136,-8.340008034,-6.17774331,-4.104502726000001,-1458.477383106947 -4602,4602,A266I,0.162639222,-0.128283154,-0.17685156,-0.066386457,-0.24631791600000003,,0.162639222,,-0.059967169,-0.128283154,,-0.17685156,,-0.066386457,,-0.24631791600000003,,1.577214132,2.155083963,-7.742071185,-7.810437935,-7.847771866,-8.836214111,-6.9441707,-7.271761314,-4.735737828,-3.0565022219999998,-1455.2560583609156 -4603,4603,A266H,0.395601821,-0.004856734000000001,-0.065801242,-0.011242262,-0.00282678,,0.395601821,,-0.041560177999999996,-0.004856734000000001,,-0.065801242,,-0.011242262,,-0.00282678,,1.340953251,2.612234521,-9.998361209,-12.16593826,-9.594224266,-11.02974333,-9.094475098,-8.107425095,-5.4981294510000005,-3.344430205,-1454.979753564112 -4604,4604,A266K,-0.351159866,-0.056209012,-0.172911542,-0.069206022,-0.193697368,,-0.351159866,,-0.112633107,-0.056209012,,-0.172911542,,-0.069206022,,-0.193697368,,1.440037801,2.125370507,-7.974927737000001,-10.09508927,-6.280436195,-9.576574768,-6.556133965,-7.366404488,-3.996761111,-0.973117993,-1457.65865765512 -4605,4605,A266M,0.34603790700000003,-0.019240548,0.04152471,0.03608576,0.062910106,,0.34603790700000003,,0.11953191099999999,-0.019240548,,0.04152471,,0.03608576,,0.062910106,,1.20498797,2.904508155,-10.01064075,-10.97800371,-8.981156006,-11.61887756,-10.30487699,-8.170289505,-6.891870127000001,-3.844259075,-1457.0883173434995 -4606,4606,A266L,0.37505988700000004,-0.081977752,-0.056799224,-0.009644789,-0.008888088,,0.37505988700000004,,0.017646771999999998,-0.081977752,,-0.056799224,,-0.009644789,,-0.008888088,,1.287897993,2.596848787,-7.8031871839999996,-8.377955833,-6.980594543,-9.789633011,-8.096917603,-5.77083493,-3.451767255,-1.2713776190000001,-1454.2098363968544 -4607,4607,A266N,0.37774374200000005,-0.10257775400000001,-0.073634209,-0.0024391020000000003,0.08711741,,0.37774374200000005,,0.068568172,-0.10257775400000001,,-0.073634209,,-0.0024391020000000003,,0.08711741,,1.215730156,2.850969187,-10.28339501,-13.39398823,-10.64214191,-12.18014978,-9.699234589,-5.501460563999999,-5.700605346000001,-1.420583421,-1455.3789170891978 -4608,4608,A266Q,0.228487823,0.014199503999999998,-0.10046496699999999,-0.023102157999999998,-0.066046697,,0.228487823,,-0.012653862,0.014199503999999998,,-0.10046496699999999,,-0.023102157999999998,,-0.066046697,,1.323575639,2.34226023,-7.997626971,-9.324178291,-7.001599434,-8.656268447999999,-7.305933112999999,-7.700155571,-3.8692733999999995,-1.482195156,-1462.4425570084713 -4609,4609,A266P,0.270350037,-0.057978523,-0.041024541,-0.174650781,-1.653566087,,0.270350037,,-0.011037471,-0.057978523,,-0.041024541,,-0.174650781,,-1.653566087,,1.210007353,1.35822011,-6.962914457999999,-9.598865906,-6.466596924,-7.479864662000001,-7.487980437999999,-3.7812643589999997,-4.093011225,-0.8461807370000001,-1453.4049414079636 -4610,4610,A266S,0.342687258,-0.031926298,-0.024562632,0.013874632,-0.018780831,,0.342687258,,-0.029094093999999997,-0.031926298,,-0.024562632,,0.013874632,,-0.018780831,,1.084257502,2.531067067,-4.845742529,-6.183047615,-4.620822983,-5.760386131000001,-4.541211754,-3.123244164,-4.170367827,-1.842786845,-1459.17919290578 -4611,4611,A266R,0.318462859,-0.053024392000000004,-0.058928724,-0.0035292929999999998,-0.0033143129999999997,,0.318462859,,-0.006296708000000001,-0.053024392000000004,,-0.058928724,,-0.0035292929999999998,,-0.0033143129999999997,,1.187372712,2.582314897,-7.651654289,-9.359199837,-5.270740295,-8.895946067999999,-5.848240722999999,-8.884144524,-4.005418543,-1.3899803080000002,-1453.01575143449 -4612,4612,A266T,0.140331348,-0.06770393200000001,-0.031762258,-0.008374882,0.018746703,,0.140331348,,-0.039526008,-0.06770393200000001,,-0.031762258,,-0.008374882,,0.018746703,,1.32210033,2.819818423,-4.942971735,-4.974907532,-5.545647827000001,-5.968902817000001,-4.4679534069999995,-3.75744709,-3.900351198,-1.9959591890000001,-1459.389355063904 -4613,4613,A266W,0.377702152,-0.084947144,-0.08161323599999999,-0.001309972,-0.663916399,,0.377702152,,-0.019545738,-0.084947144,,-0.08161323599999999,,-0.001309972,,-0.663916399,,0.94292984,1.4689113280000001,-13.73109786,-14.65528414,-13.19512041,-16.38514017,-12.860026800000002,-11.55991778,-8.295016865,-5.767743586,-1452.8629044545814 -4614,4614,A266V,0.254376094,-0.019583128,-0.062954898,-0.029222623,-0.017698685,,0.254376094,,-0.019365261,-0.019583128,,-0.062954898,,-0.029222623,,-0.017698685,,1.543610422,3.106887046,-5.093455186,-5.759747803,-5.173669151,-6.429858025,-4.742464447,-3.361536507,-3.987818968,-1.7647184280000001,-1457.9362005605362 -4615,4615,A266Y,0.400417842,0.0059141309999999996,-0.14388835,-0.037100529,-0.05505783400000001,,0.400417842,,0.099842444,0.0059141309999999996,,-0.14388835,,-0.037100529,,-0.05505783400000001,,1.456235439,2.55298152,-12.25742843,-12.64483664,-12.3985679,-15.19356399,-11.50240115,-9.547772491,-5.817980467000001,-2.904006218,-1449.0010352083482 -4616,4616,T267A,0.03211872,-0.006044195,-0.01483234,-0.009837333,-0.036951636,-0.018845395,0.030240737,0.033996702000000004,0.033248937,-0.049205145,0.037116756,-0.021773687000000003,-0.007890993,-0.027901755,0.008227089,-0.055808522,-0.018094749,1.3873978809999998,2.505001121,-3.255449571,-2.3577817690000002,-3.271479462,-4.3259276280000005,-2.823833847,-3.498225151,-3.5009302630000003,-0.312082038,-1461.5220717280172 -4617,4617,T267C,0.052386228,-0.007988031,-0.017080153,0.016619859,-0.12178815400000001,-0.001304381,0.048250601,0.056521854,0.012554947,-0.070516827,0.054540765,-0.016327905,-0.0178324,0.00561382,0.027625897000000003,-0.10771884400000001,-0.135857463,1.1764504690000002,2.129149516,-8.903374516,-7.485360588,-9.472220299,-9.863099419,-8.662179108,-9.034013168,-9.301718035,-7.784834906,-1459.6660291389562 -4618,4618,T267E,0.018413898999999997,0.014205472,-0.012188842,-0.033622154,-0.06588998900000001,-0.015705672,0.01059256,0.026235237999999998,0.036998691,-0.0015499589999999998,0.029960902999999997,-0.024390584,1.29e-05,-0.051035639,-0.016208669,-0.087593311,-0.044186666,1.400858968,2.3718612130000003,-4.128007426,-3.669506615,-4.261348152,-6.183581947,-2.679595703,-3.846004715,-4.299408328,-0.308536818,-1459.4754010620527 -4619,4619,T267D,0.061858767,-0.027677447999999997,0.009052366,-0.010730389,-0.036252419,0.029058135,0.05749765,0.066219884,0.048856577000000005,-0.06579162,0.010436724,-0.007860925999999999,0.025965658,0.00976978,-0.031230557000000003,-0.043956457000000004,-0.02854838,1.30825329,2.4626432769999997,-3.4063753460000004,-3.018718948,-5.195660995,-4.065742531000001,-2.483276581,-2.268477676,-2.79502083,1.541141925,-1461.1124771870673 -4620,4620,T267G,0.010315961,-0.017527341000000002,-0.035547423,-0.007020734,-0.024747957,-0.022717051000000002,0.0062245059999999994,0.014407415,0.040941757,-0.03663045,0.001575768,-0.018681014,-0.052413832,0.00040683,-0.014448298,-0.014541433000000001,-0.03495448,1.210797152,2.526777108,-4.98173965,-4.02829277,-4.5015637889999995,-5.945257499999999,-5.067787972,-5.365796219,-4.370599726,-0.786540949,-1462.1426845174283 -4621,4621,T267F,0.000910825,0.005383098,-0.00542894,-0.004803304,-0.90864056,0.024608988999999998,0.004806471,-0.002984821,0.046489370999999995,-0.003090474,0.013856668999999999,0.013920623,-0.024778502,-0.011535136000000001,0.0019285279999999999,-0.627623814,-1.189657305,0.593006041,1.385254969,-8.949584862,-7.236138779,-10.97009499,-10.07858456,-7.793717125,-8.669388855,-7.2094124520000005,-3.768400077,-1457.4406765634194 -4622,4622,T267I,0.045688049,-0.026957818999999997,0.005237958,0.000362835,-0.28823761800000003,-0.054456405,0.064213678,0.02716242,0.002349416,-0.076006548,0.022090911,-0.016885516,0.027361431000000002,-0.038437775,0.039163445,-0.249389463,-0.327085773,1.254612817,1.924629416,-7.990148303,-6.899457901,-8.301415732999999,-9.220891014,-7.895884682,-7.633092186,-6.809061037,-3.355514165,-1458.7911637397483 -4623,4623,T267H,0.037923684,0.012100927,0.009698776,-0.027518157999999997,-0.034456457999999995,-0.028717992,0.02055315,0.055294217,0.057467101,-0.02328553,0.047487384,-0.000500253,0.019897805,-0.022008049,-0.033028267,-0.049272559,-0.019640357,1.321427578,2.414619047,-6.873257555,-5.648542435,-8.540943253,-7.926379997000001,-4.910652985,-7.339769104,-5.275638569,-1.6164004980000002,-1457.338963679038 -4624,4624,T267K,-0.03611238,-0.014509778999999999,-0.018261061999999998,-0.063844271,-0.121983019,-0.042151835,-0.036885712,-0.035339047,0.088986119,-0.055874952,0.026855395,0.0016696920000000002,-0.038191816,-0.08710999900000001,-0.040578542,-0.04647047,-0.197495568,1.221921648,2.3451008030000002,-4.603173033,-4.25847625,-5.786440056,-5.705941887000001,-2.955097977,-4.309908997,-4.649029807,-1.30458173,-1458.802540056873 -4625,4625,T267M,-0.008897263,0.008307999,-0.009642578,-0.015124475,-0.172746861,-0.029690465,-0.061562867,0.043768340999999995,-0.025272205,-0.025207733,0.041823731,0.01200675,-0.031291905,0.024637057,-0.054886007,-0.14197628199999998,-0.203517439,1.352136281,2.22547064,-8.39117921,-7.0232622529999995,-9.524322037000001,-9.651534805,-8.062188965,-7.69458799,-6.963229811000001,-3.98240907,-1460.3576638931409 -4626,4626,T267L,0.0027207209999999997,-0.009713904,-0.028805222000000002,-6.670000000000001e-05,-0.154958829,-0.000711953,-0.007764748,0.013206188999999998,0.037062531,-0.04505272,0.025624912000000003,-0.016498233,-0.041112211,-0.019024258,0.018890904,-0.148005568,-0.16191209,1.419723899,2.2373952530000003,-7.817072112999999,-6.0079086760000004,-8.935391541,-9.564654678,-7.686483977999999,-6.890921692,-5.750315952,-2.8720172269999997,-1455.9584851814434 -4627,4627,T267N,0.019529344,0.037702328,-0.018547291,-0.008369744,0.07182240200000001,-0.043361142000000005,-0.033438609,0.072497296,0.00852039,-0.000650399,0.076055054,-0.012979435,-0.024115147000000003,0.047568923,-0.064308411,0.017068227,0.126576576,1.106124803,2.581262974,-3.955632893,-3.500690857,-5.487015952999999,-3.554760078,-3.170759445,-4.064938133,-4.17054663,-0.055879196,-1463.7170350276865 -4628,4628,T267Q,0.008167373,-0.02651603,-0.007097838,-0.024037403,-0.078434605,-0.015682951,0.031362216,-0.01502747,-0.007958884,0.011592419,-0.064624479,0.02033099,-0.034526666,0.017150749,-0.065225554,-0.040019739,-0.11684947,1.263908535,2.456590378,-5.793194141,-4.276433571,-6.845551781,-7.625619507000001,-4.064447113,-6.153918732,-4.9400459969999995,-0.9730085940000001,-1460.2239047717303 -4629,4629,T267P,0.02059026,-0.002914247,-0.016694784,-0.00839914,-0.002425347,-0.009897896,0.015271322,0.025909197999999998,0.018311978,-0.035202189,0.029373696,-0.021112693999999998,-0.012276873,-0.031162145,0.014363865,-0.030052357999999998,0.025201665,1.039176675,2.29824289,-2.859259259,-2.109662727,-1.821796974,-4.480303108,-3.051701172,-2.8328323139999996,-3.0001995339999996,-0.082581052,-1460.90924348915 -4630,4630,T267S,0.025183801000000002,0.011991652,-0.013140151999999999,-0.003108123,0.006278958,0.0035694240000000003,0.015119255,0.035248347,0.026973967999999997,-0.004064626,0.02804793,-0.014941042,-0.011339261000000002,-0.007085261,0.000869015,0.001946152,0.010611764,1.269608364,2.781116593,-0.450986351,0.292122444,-0.36862252799999995,-0.562178108,-0.525494385,-1.0907591779999999,-2.407859556,0.795068914,-1463.253852918744 -4631,4631,T267R,0.02113183,-0.012404533,-0.046325991,-0.005726378000000001,-0.101628915,-0.012564825,0.017752558999999998,0.024511099999999997,0.047787156,-0.056531787,0.031722722,-0.038460142,-0.054191839000000006,-0.028401947,0.016949191000000002,-0.092651755,-0.110606074,1.38287457,2.312930052,-6.026580502000001,-4.9451852039999995,-6.508542847,-7.726665702999999,-4.9833727869999995,-5.969135971,-5.377578659,-1.235775358,-1456.3046465772204 -4632,4632,T267W,-0.016843853,-0.008948143,-0.025229775,-0.028948132999999997,-1.686777913,-0.041581739,-0.025017234,-0.008670470999999999,0.006202142,-0.033081608,0.015185323,-0.031691856000000004,-0.018767693999999998,0.012874781,-0.07077104599999999,-1.562030605,-1.811525221,0.7211428409999999,1.318600446,-10.08778003,-8.461348816000001,-11.17075563,-11.49661557,-9.372375832000001,-9.937804306,-8.526535907000001,-5.501191559,-1452.4581754733808 -4633,4633,T267V,0.012456952,-0.026528242,-0.024470423999999998,-0.01012388,-0.11003080400000001,-0.00334005,0.00293946,0.021974444,0.06191740900000001,-0.061753757,0.008697274,-0.018002919,-0.030937927999999996,-0.012071091,-0.008176668,-0.111509717,-0.10855189,1.463126322,2.369827496,-5.8761054260000005,-5.100013054,-5.732343796,-6.966497261000001,-5.742238388,-5.8394346310000005,-5.723408009,-1.898301145,-1460.3726514163427 -4634,4634,T267Y,0.012717865,-0.021391266000000003,-0.054047465,-0.025338292999999998,-1.040756044,0.031263901000000004,0.032958646,-0.007522916,-0.010151669,-0.082301345,0.039518813,-0.046377485,-0.061717445,-0.046798745,-0.003877841,-0.787811555,-1.2937005320000001,1.070974179,1.474675182,-8.932333969,-7.231935088999999,-11.11934265,-9.673723946,-7.599572097999999,-9.037096062,-6.692925279,-3.260841987,-1452.1327603654936 -4635,4635,M268A,0.028022633999999998,0.00181098,0.044088028,-0.000479489,-0.68416902,-0.106105774,0.039725257,0.016320011000000002,-0.093096223,0.008390383000000001,-0.004768424,0.018469469,0.069706587,-0.017796991,0.016838014,-0.51010241,-0.85823563,0.713424196,1.4387268619999998,-5.836268771,-4.934040726,-4.700607636,-6.773074318,-7.563693152999999,-5.209928024,-4.415452588,1.80880537,-1450.07228903519 -4636,4636,M268C,0.082805197,0.0032241590000000003,0.075770314,0.002473344,-1.6200068,-0.133695215,0.092384275,0.073226119,-0.021193027000000003,-0.008631166,0.015079483000000001,0.042704179,0.108836448,0.050167776,-0.045221088,-1.4417212819999998,-1.7982923180000001,0.7098239120000001,1.325910141,-10.6506174,-10.08426623,-9.269208977,-11.41772983,-11.73278481,-10.74909715,-9.576490197,-7.088049726,-1450.737555688247 -4637,4637,M268E,-0.025403508999999998,-0.01330414,0.018856714,-0.022577656,-1.7215773509999999,-0.107603036,-0.030769456,-0.020037561000000002,-0.033942224,0.040645152999999996,-0.067253432,-0.001750609,0.039464036,-0.006397233,-0.038758078,-1.3571262169999998,-2.086028484,0.74592107,1.333068599,-8.965994157,-8.873480026000001,-7.351934868,-9.794858421,-10.02484447,-8.784852997,-4.512979099,0.743119368,-1443.1565501876175 -4638,4638,M268D,0.049559694,0.028195345,0.07424284,-0.004221616,-1.304387473,-0.136454111,0.032070072000000005,0.067049315,-0.012517559,0.049534085,0.006856605,0.011596012,0.136889667,-0.003517083,-0.004926148,-1.31264356,-1.2961313859999999,0.6831222509999999,1.329731004,-8.655913069,-8.121978897,-8.318828987,-9.431975624,-9.434560875,-7.972220963,-3.985179467,0.916457321,-1441.6494827861898 -4639,4639,M268G,0.02292139,0.0193231,0.068683225,0.010629656000000001,-1.144386625,-0.102823661,0.029319029,0.016523751,-0.062661534,0.047815919000000005,-0.00916972,0.047167943,0.090198506,0.005485635,0.015773676,-0.828937425,-1.459835824,0.69215041,1.372410614,-8.51344326,-8.118465034,-8.056979355,-8.565453255,-9.500549026,-8.32576963,-5.054692613,-0.283474921,-1454.1438982831314 -4640,4640,M268F,0.033353528,-0.062578457,0.014290657,-0.04316767,-0.117011117,-0.026667793,0.063537845,0.00316921,-0.083314192,-0.064973928,-0.060182985999999994,-0.032043969,0.060625282,-0.06586419,-0.020471148999999998,-0.089679706,-0.144342528,1.498346185,2.484717432,-2.261966063,-2.458199707,-0.469075829,-2.795057747,-2.072433563,-3.5150634689999998,-3.4209918530000003,0.0177629,-1465.1261716079898 -4641,4641,M268I,-0.001496065,0.057875014,0.090556975,0.056882353,-0.068482321,0.029583121,0.010712103999999998,-0.013704233,-0.085637899,0.10055143400000001,0.015198594,0.077835663,0.103278286,0.087481288,0.026283417000000003,-0.047065109,-0.08989953199999999,1.28675207,2.551786355,-2.401178044,-3.032053986,-1.9335611190000002,-2.155156891,-2.583850685,-2.30126754,-3.51199769,-0.44261181200000005,-1455.9420518800616 -4642,4642,M268H,0.038575572,0.008781273000000001,0.046621277999999995,0.001992934,-0.644612417,-0.131856989,0.052765327,0.024385817,-0.063784701,0.00374099,0.013821555,0.0015921820000000001,0.091650374,0.003808396,0.000177472,-0.499021861,-0.790202973,1.3954915540000001,1.773955546,-10.43987309,-11.12247461,-7.735003464,-11.63664337,-10.810512300000001,-10.8947317,-6.719768196,-1.190047857,-1452.147611525841 -4643,4643,M268K,0.006216201,0.031239483,0.05780349,0.013144583,-1.519471323,-0.109617614,0.010645461,0.00178694,-0.06570203,0.048069312999999995,0.014409653,0.057849892,0.057757087,0.058045482999999995,-0.031756318,-1.348765419,-1.690177227,0.574288409,1.32060653,-7.917690201,-6.747980277999999,-6.907358742,-8.826274437,-9.495972252,-7.610865295,-4.864241378,-0.8899661329999999,-1447.5533013907261 -4644,4644,M268L,0.014769506000000002,0.016643451,0.053684337,-0.0026884490000000003,-0.078608888,-0.023333704,0.033846215,-0.004307203,-0.065944611,0.037797356000000004,-0.004510455,0.01350615,0.093862524,0.009980349,-0.015357246000000001,-0.058765038,-0.098452737,1.35503312,2.454176044,-1.7229785130000002,-1.94728965,-1.16584848,-1.469435661,-2.635960495,-1.396358276,-2.3350306069999998,0.48019009700000004,-1457.558232145384 -4645,4645,M268N,0.015316806,0.008046075,0.03604879,-0.017395317,-0.97278755,-0.059982500999999994,0.039555816,-0.008922204,-0.049154338,0.060901660999999996,-0.044809510999999996,0.05492667,0.017170908999999998,0.04380541599999999,-0.07859605,-0.686175663,-1.259399436,0.594349228,1.376528205,-9.497814194,-8.954752563,-8.446674973,-9.469679176,-11.07690672,-9.541057533,-5.6883705739999995,0.19122663899999998,-1447.352535879705 -4646,4646,M268Q,0.0066756409999999995,0.011014373999999999,0.040575623,0.010439831,-0.5881475079999999,-0.090680076,0.015438134,-0.002086852,-0.035106212000000005,0.021182521,0.000846226,0.007162203000000001,0.073989042,0.03027648,-0.009396818000000001,-0.408099754,-0.768195262,0.944328774,1.56916387,-9.022070648,-8.198333984,-7.170684196,-10.14937446,-10.37732929,-9.21463131,-5.471202571,0.40354730299999997,-1451.4554903586395 -4647,4647,M268P,-0.025339066,0.012548151,0.053719085,-0.010209923000000001,-0.665290805,-0.09524845800000001,-0.021348835,-0.029329297,-0.07354654299999999,0.031901041,-0.006804739000000001,0.045670109,0.061768061,-0.005047329000000001,-0.015372516999999999,-0.474359695,-0.856221915,1.137036883,1.6208211680000002,-5.893184334,-4.703662521,-5.119691834,-6.555620514,-6.951009552,-6.135937247999999,-4.647321825,-0.227785848,-1440.819433983881 -4648,4648,M268S,0.027183596,0.004268478,0.052981494000000004,0.003781332,-0.823971461,-0.100674754,0.052093667,0.002273525,-0.05521974599999999,0.012769488,-0.004232532,0.015448443000000001,0.090514545,0.022158779,-0.014596116000000001,-0.645963591,-1.00197933,0.657247371,1.39387013,-6.548250322,-5.0516698380000005,-5.004062248,-7.253809813999999,-7.957999001,-7.473710709,-4.237564153,-0.130169311,-1448.5450206031092 -4649,4649,M268R,0.017703935,0.000784066,0.041178194,-0.021773518,-1.4262330859999999,-0.10689817,0.034836046,0.000571824,-0.06306885200000001,0.012880243000000001,-0.011312112,0.016945289,0.065411099,-0.026772577000000002,-0.016774458,-1.244938619,-1.6075275519999999,0.9268493,1.36305355,-8.132532494,-6.481900252999999,-6.266915627,-9.116715881000001,-9.923524857,-8.87360585,-4.4124972069999995,0.024086307,-1451.1095281820744 -4650,4650,M268T,0.007653910999999999,0.012619863,0.049142689,-0.004214333,-0.601201794,-0.08482651199999999,0.020362385,-0.005054564,-0.046460419,0.037361978,-0.012122253000000001,0.032333621,0.065951757,-0.01256315,0.004134484,-0.421223316,-0.781180271,0.914113788,1.554296162,-6.178755037,-5.8517212910000005,-4.862786659,-6.981656029,-7.348989242999999,-5.8486219639999995,-5.096371896,0.040626767,-1451.2260132050142 -4651,4651,M268W,-0.004153718,0.031237211,0.04557365,0.000706916,-0.249969002,-0.011602582,-0.032244917000000005,0.023937481,-0.083850833,0.057575757000000005,0.0048986640000000005,0.01452416,0.076623139,0.015729777,-0.014315946000000001,-0.178129622,-0.321808382,1.524120394,2.287724827,-8.215593687,-8.339175888,-6.715449233999999,-8.196621863999999,-9.488346466,-8.338374985,-7.7199340770000004,-4.209013455,-1455.2540524937212 -4652,4652,M268V,0.042375064000000004,-0.00012037799999999999,0.048121945,0.017640563999999997,-0.21220918,-0.066274742,0.063631004,0.021119122999999997,-0.034453793999999996,0.01527118,-0.015511935,0.009329466,0.086914424,-0.0020465410000000002,0.037327668,-0.15498900000000002,-0.269429359,1.249041308,2.076863988,-3.574595856,-3.953622078,-2.307736961,-3.5189147569999997,-3.984887398,-4.107818085,-4.599357159,-0.23475161,-1454.1967579475604 -4653,4653,M268Y,-0.030099196,-0.002161302,0.00696042,-0.060742937999999996,-0.670814771,-0.053358800000000005,-0.029492392000000003,-0.030705998999999998,-0.037330952,0.028046725,-0.032369327999999996,-0.01087392,0.024794759,-0.078375085,-0.04311079,-0.482572404,-0.8590571379999999,1.5026274659999999,1.8495217030000002,-7.026033900000001,-7.653235947000001,-5.527852211,-6.993723747000001,-6.635228119,-8.320129478,-6.132814914,-1.142366709,-1463.0136602879502 -4654,4654,D269A,0.051102666,-0.035273753,0.036073834,0.0034933259999999997,-0.017503169,-0.003989707,0.057147643,0.045057689000000005,-0.05294694900000001,-0.033426776,-0.03712073,0.019110876000000002,0.05303679099999999,0.026735019,-0.019748368,-0.027523005,-0.007483332,1.335942157,2.579761923,-0.674442964,-1.014336182,-0.404730972,-1.200135452,-0.49308329799999995,-0.259928917,-2.9644033110000003,0.657361391,-1457.445116291754 -4655,4655,D269C,-0.030770863,-0.047987552,0.035372827999999995,0.012540753,-0.248746876,-0.044170713,-0.06494373,0.003402005,-0.023248827000000003,-0.016819614,-0.07915549,0.032071743,0.038673912000000005,0.053870392999999996,-0.028788888,-0.219037772,-0.27845597899999996,1.15441025,1.9221092380000002,-8.174430284,-8.617481384,-8.296215332000001,-9.277652939,-7.714647437999999,-6.966154327000001,-8.739158639,-7.825748977000001,-1458.4241594872437 -4656,4656,D269E,0.069690628,-0.022694297000000002,0.063534603,0.010276244,-0.028764448999999997,0.003450122,0.095048891,0.044332365,-0.005995537,-0.027233043999999998,-0.01815555,0.019180088,0.107889118,0.005166512,0.015385975,-0.051776836,-0.005752062,1.246647087,2.42582167,-0.96290901,-1.5188970259999999,-0.393354507,-1.40404631,-0.484152084,-1.014095123,-2.007282661,0.637694037,-1458.5808778228238 -4657,4657,D269G,-0.014087448999999998,-0.047609230999999995,0.025288663,-0.01368996,-0.055161395999999994,-0.036859391,-0.028955372000000004,0.000780474,-0.017765658,-0.014858583,-0.08035987900000001,0.05014948,0.000427846,0.050443311,-0.07782323,-0.039782219,-0.070540572,1.126542494,2.431668703,-3.863792229,-4.5040758819999995,-2.902243027,-4.477942627,-3.418045425,-4.016654182,-3.7127308269999997,-1.053526039,-1457.6731003751047 -4658,4658,D269F,-0.009014459,-0.036679361,0.03621572,-0.026963981,-0.12785417400000001,-0.056867935999999994,-0.030690704,0.012661786999999999,-0.0071490419999999995,-0.037827995,-0.035530727000000005,0.072120209,0.000311231,0.008382588,-0.06231054900000001,-0.073383082,-0.182325265,1.381488188,2.474124857,-7.864631913999999,-8.34650367,-8.374730827,-8.992585808,-7.73060006,-5.8787392039999995,-6.210028952999999,-3.0156478669999998,-1452.621512368787 -4659,4659,D269I,0.173859801,-0.014213368999999998,0.018566311000000002,0.016979829,-0.008056493,-0.054091047,0.161908955,0.18581064600000002,0.045683539,-0.10351910199999999,0.07509236400000001,-0.064256383,0.101389005,-0.056088007,0.090047664,-0.10326316199999999,0.087150176,1.490862979,2.350063778,-5.883578241,-6.244813026,-5.8621764910000005,-6.855109688,-5.716116669,-4.739675331,-5.766905226,-2.271021291,-1451.582088922616 -4660,4660,D269H,-0.046883775999999995,-0.066250988,0.068053543,-0.021062612,-0.07581602,-0.018070605,-0.081046964,-0.012720588,0.043668248,-0.028394626,-0.104107349,0.059739308,0.076367777,0.036635161,-0.078760384,-0.029540275,-0.122091764,1.22273188,2.520490165,-4.60961597,-4.090373688000001,-5.007695686,-5.853297386,-3.8763616180000002,-4.220351471,-5.450312124,-2.08337262,-1454.5323273087852 -4661,4661,D269K,-0.099158329,-0.110053949,-0.083752889,-0.122898966,-0.127878216,-0.11162422400000001,-0.142661639,-0.05565501900000001,0.012271235,-0.059174961,-0.160932936,-0.008045898000000001,-0.159459879,-0.104640483,-0.14115744800000002,-0.157230622,-0.098525809,1.456416069,2.23460833,-1.952627034,-2.313077362,-2.2424673999999998,-3.344438171,-1.05825396,-0.804898277,-1.7232706080000002,0.10754752699999999,-1449.6343501904048 -4662,4662,D269M,0.043389405,-0.071248708,0.002566298,-0.024322301,-0.063459543,-0.03200592,0.031549753,0.055229057000000005,-0.035757211000000004,-0.07966949200000001,-0.062827923,-0.06523035599999999,0.07036295099999999,-0.06503091,0.016386308,-0.107984804,-0.018934281,1.414112611,2.3879598580000003,-6.734389998999999,-7.187047043,-6.965687141,-7.433446067999999,-6.4877101139999995,-5.598059631,-6.042017246,-3.4163557669999998,-1452.2902529183775 -4663,4663,D269L,0.047875269000000005,-0.031406776000000004,0.042570263,0.006769323000000001,-0.07140762,-0.006988763,0.048120807,0.04762973,-0.031450713,-0.008431788,-0.054381764000000006,0.036688985,0.048451540999999994,0.030609887000000002,-0.017071242,-0.089446235,-0.053369004000000005,1.3217134959999999,2.361110558,-5.789163791,-6.351070517999999,-6.112086037,-6.636318169,-5.439526604,-4.406817627,-5.030517318999999,-1.729795671,-1451.1060462854803 -4664,4664,D269N,0.016199764,-0.005721141999999999,0.08172407,-0.019859105,-0.039656706,-0.014000137,-0.0041564340000000005,0.036555961,-0.050249432999999996,-0.008059304,-0.00338298,0.111476621,0.051971519,0.014113471,-0.053831681,-0.04857385,-0.030739562,1.372238555,2.532056121,-2.615338319,-2.5146450419999997,-2.649364311,-3.3737269519999997,-2.367295242,-2.171660049,-2.759974525,-0.54730329,-1460.9024688708596 -4665,4665,D269Q,0.00181108,-0.040102944,0.024425894,-0.016140259,-0.07497792,-0.111944763,-0.031600861,0.035223021,0.057921743,-0.037712083,-0.042493805,0.0030831770000000003,0.04576861,0.05864754,-0.09092805699999999,-0.069691642,-0.080264197,1.244562121,2.363300113,-2.825870198,-3.597037498,-2.875212326,-3.781540764,-2.413122101,-1.462438301,-3.8200579969999997,-0.8189439620000001,-1457.081837757025 -4666,4666,D269P,0.021723585,-0.038386716,0.006374778,-0.011030802,-0.09725395099999999,-0.05058156900000001,0.019002346,0.024444824,-0.042526189000000006,-0.017607266,-0.059166165,0.002257383,0.010492173,0.039616616,-0.06167822,-0.092860079,-0.101647822,1.4304503130000001,2.455656409,-2.6604151469999997,-4.033313049,-2.8951815869999997,-2.771419807,-2.210753395,-1.3914078980000002,-2.893227374,0.77993807,-1457.317991138436 -4667,4667,D269S,-0.01871066,-0.049684078,1.21e-05,0.010309779,-0.041011648,-0.035341633,-0.031269003,-0.006152316,-0.035036898,0.00403087,-0.103399025,0.066390582,-0.066366468,0.071654269,-0.051034710999999996,-0.037176777,-0.044846517999999995,1.3726640069999998,2.687981633,-2.357086189,-3.076577683,-2.187303337,-3.0809495539999996,-2.174569176,-1.266031197,-3.0003469760000003,-0.7918456859999999,-1460.263503702823 -4668,4668,D269R,-0.00517351,-0.056264374000000006,0.009622668000000001,-0.023041055,-0.115253874,-0.040144037,-0.020781741,0.010434721,-0.054668734000000004,-0.034857697,-0.07767105,0.009543546,0.009701789,0.015566232,-0.061648340999999995,-0.102670105,-0.127837643,1.4102138380000002,2.421800229,-3.455981917,-3.6857695689999996,-3.3976728210000005,-4.634147186,-2.9143128739999997,-2.648007133,-4.702547644,-0.971151257,-1445.0915513425134 -4669,4669,D269T,0.031119606,-0.043040630999999996,0.039245758,0.011763764,-0.040370777000000004,-0.019499406,0.00569136,0.056547852,-0.047339543,-0.023459409,-0.062621852,0.032858419,0.045633097000000004,0.064554285,-0.041026757999999997,-0.027152246,-0.053589307,1.3964189390000001,2.684515578,-2.429630251,-2.735876694,-2.547397865,-3.380374435,-1.579773285,-1.904728973,-2.8124337789999996,-0.5746494000000001,-1461.3400537278503 -4670,4670,D269W,0.014771783,-0.09888849699999999,0.045701301,-0.044088059000000006,-0.17828193,-0.018523331,0.011422298999999999,0.018121267,-0.01534352,-0.070227935,-0.127549059,0.084389903,0.007012698,-0.009831863,-0.078344254,-0.13791394,-0.21864992,1.3617598480000002,2.235593191,-8.125564102,-8.473323181,-8.180314888,-9.229200714,-7.9967837070000005,-6.748198021,-6.860639339,-4.429510195,-1451.8208651253954 -4671,4671,D269V,0.0033106340000000002,-0.08435041300000001,0.012678241000000002,-0.046586452,-0.059219047000000004,-0.016439551,0.004220794,0.0024004729999999998,-0.005018627,-0.082364699,-0.086336127,0.00379689,0.021559592000000002,-0.025878517,-0.067294387,-0.076527508,-0.041910586,1.282274329,2.283398773,-3.705761815,-3.718711266,-3.629392029,-4.516423828,-3.7501595689999996,-2.914122383,-4.064445108,-1.005542191,-1454.6117973164655 -4672,4672,D269Y,-0.010307908000000001,-0.11809160699999999,-0.052462603,-0.050583308,-0.12499882699999999,0.020011073,-0.049679065,0.02906325,-0.08767428599999999,-0.09604189099999999,-0.14014132199999998,-0.050340486,-0.05458472,0.037281336,-0.13844795199999999,-0.082701389,-0.167296265,1.356455985,2.37120265,-6.630472472,-6.626988792000001,-8.1744925,-7.925972389,-5.716406578,-4.708502098,-5.608159553999999,-1.965443775,-1452.9372716252692 -4673,4673,E270A,0.091651093,-0.023237382,0.037808646,0.197033925,0.078759389,-0.02456431,0.062776848,0.120525337,0.07186695400000001,-0.019212703,-0.02726206,-0.088314115,0.163931407,0.123685134,0.270382716,0.039040369,0.11847840800000001,1.027434188,2.893681162,-2.823240953,-2.524744736,-2.7061158069999998,-3.2582043689999995,-2.889568604,-2.7375712510000003,-4.5319126380000005,0.076322243,-1462.5597300957888 -4674,4674,E270C,0.037849531,-0.056735985,-0.034056364,0.101675529,-0.244633761,-0.066169072,0.012326041999999999,0.063373019,0.039927947000000005,-0.055655177,-0.057816793,-0.188727007,0.12061428,-0.00085431,0.204205367,-0.20635210399999998,-0.282915417,1.393059971,2.0837291430000002,-9.484078505,-9.272044418,-9.688048126,-10.96170597,-8.699922858999999,-8.79867115,-8.105426653,-5.811157538,-1461.661207539495 -4675,4675,E270D,0.071480486,0.049407767000000005,0.113168499,0.1973616,0.111175353,-0.067214884,0.082137801,0.06082317,0.07058107400000001,-0.035874257,0.134689791,0.009029317,0.217307681,0.115000214,0.279722986,0.068048738,0.154301968,1.15557715,2.906122685,-2.8667482860000004,-2.892088852,-2.18089743,-3.552958504,-2.8407515560000003,-2.86704509,-3.390357855,-0.874838448,-1461.8361762654968 -4676,4676,E270G,0.150667204,-0.00119775,-0.039345302,0.07391824799999999,-0.5922990570000001,-0.101817035,0.136451215,0.164883193,0.10003819800000001,-0.023840909,0.02144541,-0.11965314,0.040962537,0.04441914,0.103417355,-0.386548025,-0.7980500890000001,1.055090209,1.6486648680000002,-6.127391969,-7.1113998789999995,-5.2690396580000005,-7.200362114,-4.834701126000001,-6.2214570689999995,-4.662094777,-1.391147713,-1466.955394020304 -4677,4677,E270F,0.013703646000000002,-0.049621599,-0.163358752,-0.05995315,-0.148212625,-0.178001288,0.022748066,0.004659225,-0.044582132999999996,-0.025632138,-0.07361106,-0.388180171,0.061462668,-0.179904229,0.05999793,-0.22230807800000002,-0.074117172,1.800293665,2.319079553,-8.87487885,-7.947089523,-8.940777435,-11.76601304,-8.654778038,-7.065736214,-5.558665512999999,-3.4801372880000003,-1460.8520382153802 -4678,4678,E270I,0.08447222199999999,0.019155818999999998,0.028798893,0.198463243,-0.067328252,-0.012445091,0.057431928,0.111512515,-0.027152246,-0.217605783,0.25591742100000003,-0.206125965,0.26372375,-0.106994492,0.503920978,-0.056644288,-0.078012216,1.387026486,2.343490509,-4.981078366,-4.884583359,-5.49786544,-4.932682381,-4.579838165,-5.010422485,-4.686844549,-2.440363347,-1461.8340357500128 -4679,4679,E270H,0.15592124400000001,0.003732139,-0.038773427,0.08625919300000001,-0.007309004,-0.102296379,0.154761347,0.157081141,0.09828654199999999,-0.11270428,0.120168557,-0.185725218,0.108178365,-0.101708896,0.274227282,-0.08027919,0.065661182,1.356222896,2.244818374,-6.934721574,-6.795305717000001,-7.141623245,-8.805610512000001,-7.277054512,-4.654013886,-5.926598518,-2.242733038,-1458.337273371406 -4680,4680,E270K,0.080472677,-0.147520202,0.024444241000000002,0.119127625,-0.081976048,-0.23408869399999999,-0.018288786,0.179234139,-0.096910013,-0.261357291,-0.033683113,-0.077942174,0.12683065599999999,-0.045757491,0.284012741,0.0020152910000000002,-0.165967386,1.312050494,2.647915167,-4.592292458,-5.255593567,-4.579212524,-5.390334212999999,-3.9316270980000003,-3.804694885,-4.937800765,-1.52398333,-1457.491157298442 -4681,4681,E270M,0.11793053699999999,-0.17935717199999998,-0.079502447,-0.049851457,-0.310200101,0.007087503,0.053797644000000006,0.182063429,0.164810249,-0.377522103,0.01880776,-0.38377105200000006,0.224766159,-0.159700843,0.05999793,-0.257152258,-0.363247944,2.049690423,2.5056082490000002,-5.316188264,-4.991301628,-6.156343216000001,-5.385351654,-5.576166893,-4.471777931,-4.894227677,-3.205877278,-1463.8585920576006 -4682,4682,E270L,0.108808338,-0.033873145,0.006217116,0.10767846800000001,-0.017462942,0.071375882,0.115369945,0.10224673,0.010995383999999999,-0.08473608099999999,0.016989791,-0.157637682,0.170071914,-0.038115748,0.253472684,-0.115562346,0.08063646299999999,1.310213176,2.2361428340000002,-4.230964418,-3.466830322,-5.8588928760000005,-4.616414719,-3.9792983019999997,-3.233385872,-4.340833464,-2.326500595,-1462.97804313479 -4683,4683,E270N,-0.021896967000000003,-0.214591041,-0.061553189,-0.031661058,-0.065881175,-0.047692317000000005,-0.009936710999999999,-0.033857222,0.16633142199999998,-0.081631747,-0.34755033399999996,-0.16706194300000002,0.043955565,0.057008267,-0.12033038199999999,-0.090130932,-0.041631417999999996,1.089609965,2.12619429,-5.678670201,-5.481844497999999,-6.118224297,-6.639164665,-4.613272736,-5.54084481,-4.832668534,-2.181981968,-1462.4026309689507 -4684,4684,E270Q,0.32779339,-0.18041901800000001,-0.014080337,0.030100792999999997,0.06728105200000001,-0.08403233,0.294221028,0.36136575200000004,0.246672333,-0.605295835,0.24445779899999998,-0.286155443,0.257994769,-0.149235409,0.209436994,-0.17806645100000001,0.312628554,1.693481663,2.304284563,-1.7611255680000002,-1.969540421,-2.7589512939999996,-1.398242294,-1.996290474,-0.682603355,-2.2399601959999997,-0.876759223,-1462.609511404764 -4685,4685,E270P,0.029197373,-0.023891091,-0.056959565999999996,-1.340285675,-1.986815688,-0.10611909300000001,0.0013974679999999998,0.056997277,0.00604596,-0.051357814,0.003575633,-0.141432914,0.027513782999999997,-0.9133783240000001,-1.767193025,-1.849068256,-2.12456312,2.471440835,1.77898438,-7.581453,-7.904668289,-7.333040168999999,-8.63092318,-7.2162341770000005,-6.822399185,-4.9048080810000005,-1.325246367,-1461.433284969069 -4686,4686,E270S,0.043260195,-0.017773047,0.004583866,0.101468164,-0.039686684,-0.035918412000000004,0.041107391,0.045412999,0.06366908,-0.037167325,0.001621232,-0.08984139699999999,0.099009129,0.063085908,0.139850419,-0.047672492999999996,-0.031700874,1.285933114,2.532038708,-5.68598898,-5.799924248,-5.571584763,-6.862362778,-5.055758064,-5.140315048,-4.731199162,-1.415635969,-1462.7301801312715 -4687,4687,E270R,0.049859271,-0.076785835,-0.09640856800000001,0.05169493,-0.210595029,-0.041734467000000004,0.011364338,0.088354204,0.021002947,-0.13743129,-0.016140379,-0.148494769,-0.044322367,-0.044307424000000005,0.147697284,-0.301909135,-0.11928092300000001,1.558660261,2.091780322,-4.994813402,-4.893377205,-5.176808868,-5.979057739,-5.441427979,-3.483395218,-4.115780973,-0.8618158570000001,-1450.876492379699 -4688,4688,E270T,0.141304054,0.037794904,0.002968223,0.150036634,0.0043225270000000005,-0.046202888,0.120072924,0.162535184,-0.010219165,0.022211277999999997,0.05337853,-0.113328715,0.11926516,0.07250635799999999,0.22756691,-0.011290176,0.019935229,1.243936137,2.703743926,-2.810873518,-2.093369499,-3.8940145339999996,-2.8390390930000002,-2.733845497,-2.494098969,-3.495288191,-0.8261494490000001,-1464.0001259557903 -4689,4689,E270W,-0.040624409,0.042032106,-0.053543355,0.099084282,-0.625633446,0.110624469,-0.060145709000000006,-0.021103108,0.10011515300000001,0.100018557,-0.015954346,0.079855093,-0.186941802,0.194574665,0.003593898,-0.509474865,-0.741792027,0.410732081,1.3730191980000002,-9.305013268,-9.699569504,-9.118012726,-11.14501562,-8.817969315,-7.744499176000001,-5.390238897000001,-3.1679026410000004,-1465.333200351335 -4690,4690,E270V,0.055540807000000005,-0.048362614000000005,-0.038161704,0.11561983599999999,-0.007478681,-0.03275788,0.001353778,0.109727835,0.009870754,-0.125760486,0.029035257999999998,-0.134484055,0.058160647999999995,-0.006217375,0.237457046,-0.116674496,0.101717134,1.417640351,2.2866004980000003,-2.823124092,-2.185381927,-2.8509802860000004,-2.480425499,-3.1088026660000003,-3.490030083,-4.565133199,-1.3447161890000001,-1463.2898645503446 -4691,4691,E270Y,0.114330944,-0.128712801,0.012145378,0.064690812,-0.157183129,-0.127516339,0.087655911,0.141005977,-0.083546051,-0.031204377999999998,-0.226221223,-0.169022643,0.193313399,0.050248682999999995,0.07913294,-0.16106784,-0.15329841800000002,1.250853078,2.066913331,-8.107741341,-8.404937721,-8.348278792999999,-11.12999238,-7.442288382999999,-5.213209427,-4.485849636,-1.06583056,-1461.337221337948 -4692,4692,R271A,-0.005525891999999999,0.033199527,0.039465529,0.021896495,-0.226637311,-0.011157455,0.00059959,-0.011651373000000001,-0.020114826000000002,0.078244238,-0.011845185,0.041577429,0.037353628,0.029349572999999997,0.014443416,-0.138509057,-0.314765564,1.338780602,2.222551131,-5.5785108260000005,-4.195139191,-7.7776217270000005,-5.702666344,-5.348579155,-4.868547714,-4.101888514,-0.000559988,-1452.1692538564093 -4693,4693,R271C,-0.03578944,-0.010230463,0.012696216000000001,-0.012113344,-0.16233376900000002,0.004289188,-0.0711741,-0.000404779,0.016428191,0.014550425,-0.035011351,0.04657366,-0.021181228,0.02428035,-0.048507037999999995,-0.08897446199999999,-0.235693076,1.264454929,2.305016571,-7.358436671000001,-8.264018593,-7.716170105,-7.453663033,-8.07056739,-5.287764236,-5.315231642,-3.9215264789999997,-1453.2693766932935 -4694,4694,R271E,-0.05301536900000001,0.027476642000000003,0.031208071,-0.429989016,-2.389584217,-0.067555845,-0.058059260999999994,-0.047971476,0.02274703,0.070172473,-0.01521919,0.061428715,0.000987427,-0.00868117,-0.851296862,-1.667864802,-3.111303631,0.698024895,1.3131915490000001,-10.45165013,-11.05660411,-10.06568335,-11.00951213,-12.57478398,-7.551667084,-4.909823619,-3.039044066,-1440.078146936372 -4695,4695,R271D,0.065735182,0.082801283,0.068888275,0.08581628699999999,-1.609124252,-0.091853302,0.06689617099999999,0.064574193,-0.027707467000000003,0.087219053,0.078383513,0.085752177,0.052024372,0.12115990300000001,0.050472671,-1.341387684,-1.87686082,0.49934165799999997,1.315851796,-11.19416054,-9.769874512000001,-11.71138618,-11.72797646,-12.31688966,-10.44467587,-3.782286027,-0.628842501,-1447.1842081299983 -4696,4696,R271G,0.007470401999999999,0.01804001,0.036807649,0.013305932,-0.9991883490000001,-0.067928491,0.009629181,0.0053116230000000006,0.024342446,0.022514778,0.013565241,0.033601465,0.040013832,0.0066233590000000005,0.019988505,-0.7822028940000001,-1.216173803,0.8558167990000001,1.412696736,-9.358883806,-8.851324371,-13.61061343,-9.213291161,-8.610203346,-6.508986717000001,-4.607707355,-0.788220178,-1462.0133436881006 -4697,4697,R271F,0.103431544,0.074901741,0.091394574,-1.05918513,-1.988937185,-0.103093911,0.120605407,0.08625768,-0.072476489,0.045197593,0.10460588800000001,0.052287507000000004,0.13050164,-0.742641368,-1.3757288909999998,-1.8076780909999999,-2.170196278,2.021030271,1.5441796069999998,-7.890401495,-9.506108986000001,-7.658956085,-5.69568721,-9.64809304,-6.943162155,-5.025148263,-3.0651027330000002,-1454.6973676686175 -4698,4698,R271I,0.010065736,-0.078285532,-0.034646696,-0.07030737299999999,-0.15856105,-0.05254426400000001,0.032137289,-0.012005817,0.007689382,-0.125794643,-0.03077642,-0.053362808,-0.015930583,-0.081459925,-0.059154820999999996,-0.131920975,-0.185201124,1.502699513,2.291849633,-5.916934647000001,-7.631395226,-6.042563309,-5.947433205,-5.631646568,-4.331634926,-4.7849538339999995,-2.92474801,-1449.0869898349047 -4699,4699,R271H,-0.053557452,0.040878127,0.000275945,0.0034273520000000003,-1.350593911,0.08258908599999999,-0.042915865,-0.064199038,-0.010769301,0.085509838,-0.0037535840000000003,0.078492597,-0.077940708,0.038545243,-0.031690539,-1.1186740929999999,-1.5825137280000001,0.603186059,1.334859372,-7.503212657000001,-8.513963829,-7.804603531000001,-6.758643509,-8.311483719,-6.127368698,-4.790249114,-3.254757586,-1458.06871487014 -4700,4700,R271K,-0.10971967099999999,-0.047148928,-0.035107645,-0.066985803,-0.10937738699999999,-0.022709347999999997,-0.178199868,-0.041239473,-0.020436185,-0.00192166,-0.092376195,-0.025848002000000002,-0.044367287000000005,-0.073026757,-0.060944847999999996,-0.050843892,-0.16791088199999998,1.5464736069999998,2.938183126,-6.330341576,-6.112701675,-9.364824287000001,-5.297240669,-5.855620087,-5.021321159,-4.247444078,-3.3682145269999997,-1454.4483576756902 -4701,4701,R271M,0.076466785,0.038253897,0.07728792,0.045271474000000006,-0.04327186,0.040726457,0.07158471799999999,0.081348851,-0.015404123999999998,0.060897499,0.015610295,0.062344777000000004,0.09223106199999999,0.038917537,0.051625410999999996,-0.003208796,-0.08333492299999999,1.287604928,2.657464261,-7.114774141,-8.163379059,-8.568783867,-6.822238014,-6.738262436,-5.281207329,-6.0193609189999995,-4.424314058,-1450.4280424565077 -4702,4702,R271L,0.026058122000000003,0.018060137,0.050181815,0.025077868,-0.0015712579999999999,-0.029165316,0.007923366,0.044192877,0.005769753000000001,0.010538563,0.025581711,0.025023446,0.075340183,0.008441458,0.041714278,0.000986355,-0.00412887,1.116072357,2.504805661,-1.7997309769999998,-2.0515470430000002,-2.396899033,-1.882192764,-1.6268643040000001,-1.041151741,-1.72088234,-2.309896272,-1454.7662499770522 -4703,4703,R271N,0.012852291000000002,-0.038103534,0.009957718,0.04613864,-0.209096776,0.019999018,-0.08383116,0.10953574199999999,-0.046271186,0.018687419,-0.094894486,-0.030394409,0.050309845,-0.006356591,0.098633871,-0.14494547,-0.273248082,1.325286068,2.206595872,-9.632101596,-9.66559713,-10.32803674,-9.839833244,-9.728282806000001,-8.598758057000001,-4.211968324,-1.097126517,-1454.6978851119056 -4704,4704,R271Q,-0.028169395,-0.015179038999999998,-0.009641953,0.050044658,-0.152919851,-0.050078149,-0.063873268,0.007534479,-0.075424159,-0.001365941,-0.028992137,-0.010790876000000001,-0.00849303,0.036075886,0.06401343,-0.106998744,-0.19884095699999998,1.266986491,2.216815181,-6.820826326000001,-7.568268387000001,-8.348463371,-7.45922242,-6.076279396,-4.651898056,-3.495614264,-1.9348413340000001,-1453.4630876439624 -4705,4705,R271P,-0.012033445,0.029142241,0.03268523,-0.22354957600000003,-1.75957902,-0.082940006,-0.011948516999999999,-0.012118371999999999,-0.026342761,0.048983174000000004,0.009301308000000001,0.020216348000000002,0.045154112,-0.020126558,-0.426972594,-1.667864802,-1.851293237,0.708691427,1.313370867,-10.06670939,-11.08811894,-11.11399947,-9.75744091,-9.783883804,-8.590103844,-5.584129107000001,-3.9628908610000004,-1452.410777144134 -4706,4706,R271S,0.012450006999999999,-0.0061822430000000005,0.018134179,0.026403676,-0.48528999999999994,-0.063183739,0.008724085999999999,0.016175928,-0.048366552,-0.001365941,-0.010998543999999999,-0.020953105,0.057221462,-0.007062459,0.05986981,-0.38183499,-0.58874501,1.008784361,1.620262593,-5.116396861,-4.569901917,-6.161299492,-5.654759491,-5.091296501,-4.104726906000001,-3.35408581,-1.6979162069999998,-1453.9259817115963 -4707,4707,R271T,0.004298607,0.006811419,-0.001557805,-0.046779843,-0.219194195,-0.06186127,-0.02900926,0.037606473,-0.018951604,0.032929159,-0.019306321,0.024165977999999998,-0.027281588,-0.0039083040000000005,-0.08965138199999999,-0.163111481,-0.275276908,1.476887223,2.27405069,-6.450218137,-7.0046626210000005,-6.54497789,-7.960066512999999,-5.270193358999999,-5.4711903,-5.047270664,-2.260794497,-1451.4996598279104 -4708,4708,R271W,-0.024721688,0.00600562,-0.031350643,-1.4902387469999998,-1.8522165000000002,-0.19887945699999998,-0.04065369,-0.008789686,-0.060385395,0.054957430999999994,-0.042946192,0.059190133,-0.121891418,-1.319147255,-1.661330239,-1.8105073809999999,-1.893925619,3.212294552,2.370714614,-10.36453822,-10.84102312,-10.85495948,-10.09110312,-11.12797205,-8.907633347,-7.571739833,-5.997125433,-1452.947811059188 -4709,4709,R271V,-0.027211632000000003,-0.005220443,-0.007197276,0.019706283999999998,-0.32337525300000003,-0.068569499,-0.049306079,-0.005117185,0.043408853,0.0032368920000000003,-0.013677778,-0.001679181,-0.012715371000000001,0.022568982999999997,0.016843585,-0.188333885,-0.45841662,1.3659525680000002,2.140208431,-5.672000456,-6.896708817,-5.920889824,-6.075924132999999,-5.544536858,-3.92194265,-5.1517295569999995,-1.7562200209999999,-1451.7913322169334 -4710,4710,R271Y,-0.044216372000000004,-0.021677394,0.0011154910000000001,-1.608765727,-1.8952975669999998,-0.11574367199999999,-0.082757017,-0.005675726,0.021145365,-0.012310063999999999,-0.031044724,0.000626893,0.001604089,-1.505728872,-1.7118025819999998,-2.109438607,-1.681156527,1.112417458,0.7526295209999999,-11.42812937,-14.21516967,-12.51848643,-9.646871192999999,-12.10104384,-8.659075706,-6.838377007,-4.80878227,-1455.0647247317247 -4711,4711,N272A,-0.003206595,0.037253148,0.025637893999999998,0.018814057,-1.503449934,-0.022050347999999997,0.010751236,-0.017164425,-0.301029996,0.064906639,0.009599657,0.003844158,0.04743163,0.047135961,-0.009507847,-1.47961599,-1.5272838780000002,0.5674433529999999,1.315076988,-8.695042061,-11.65709365,-9.060844521,-7.311714417,-7.767588364,-7.677969353,-6.342204122,-1.157574364,-1442.8879908914678 -4712,4712,N272C,0.002339129,0.005863978000000001,-0.009496733,-0.94739273,-2.5359068280000003,0.012800595,0.017364705,-0.012686447,-0.11868978699999999,-0.033517782999999995,0.04524573900000001,-0.058148515,0.03915505,-0.34778253600000003,-1.5470029230000002,-1.7462346219999998,-3.3255790339999995,1.575476365,1.417009194,-11.36816614,-13.24986112,-11.47356143,-9.689869186000001,-11.24678302,-11.18075592,-8.084502696,-2.7652889739999997,-1448.297726937104 -4713,4713,N272E,-0.02002424,-0.015086658000000001,-0.013248158999999999,0.018676339,-1.593646034,-0.009244002,-0.047597420999999994,0.007548941,-0.28061553100000003,-0.007314226,-0.022859089,-0.00418698,-0.022309337000000002,0.014077766,0.023274911000000002,-1.482200926,-1.705091142,0.669185008,1.319673223,-6.596958974,-9.389962364,-5.257612793,-6.011967003,-6.122048187000001,-6.203204521,-6.709522435,0.28369715,-1464.2777213300578 -4714,4714,N272D,0.035129802,0.025773967999999998,0.016224041,0.050486015,-0.07933293,-0.076551483,0.045420222999999996,0.024839381,-0.30209837100000003,0.027903636000000002,0.0236443,0.019622867,0.012825215,0.074494263,0.026477767000000003,-0.079926394,-0.078739465,1.1861484409999998,2.3014651980000003,-4.28526559,-4.910842033,-4.728871506,-3.1103451310000003,-4.544304619,-4.1319646610000005,-3.8191895419999997,0.428275896,-1463.4902410325594 -4715,4715,N272G,-0.025887632,0.00344386,-0.021010355,0.029519222,-1.6397913869999998,-0.05851241,-0.04360787,-0.008167393,-0.21641293399999997,0.044679839000000006,-0.03779212,-0.0015138670000000001,-0.040506843,0.06660418,-0.0075657369999999995,-1.507175701,-1.772407073,0.40665314799999996,1.30743929,-9.537358505,-12.81583868,-8.477954238999999,-8.924373802,-9.109165482,-8.359460327,-7.270035837000001,-2.630576544,-1449.0887824497186 -4716,4716,N272F,-0.009782553000000001,-0.209506246,-1.595318566,-1.95613561,-2.708675753,0.009510414,0.029612461,-0.049177566,0.267462648,-0.0008150410000000001,-0.41819745,-1.487009134,-1.703627997,-1.839135604,-2.073135616,-2.11939509,-3.2979564160000003,3.7927046160000004,2.2894831719999997,-12.143020300000002,-14.25903537,-12.81730621,-10.62202444,-10.01471681,-13.00201865,-8.506450573,-3.4542252419999997,-1447.9288020767272 -4717,4717,N272I,-0.078710899,0.01136864,-0.211616155,-1.5751994619999998,-2.488615886,0.018040012,-0.033071168,-0.124350629,-0.07135590900000001,0.004860737,0.017876542,-0.051104157000000004,-0.37212815299999996,-1.295269961,-1.8551289619999998,-2.221793102,-2.75543867,0.785261256,0.7315211540000001,-12.72876414,-15.03703909,-15.9364978,-12.71388398,-10.22538979,-9.731010071,-8.524841006,-2.0566209140000002,-1438.0721203428693 -4718,4718,N272H,-0.012431018,-0.001819407,-0.014202943999999999,-0.45668361700000004,-1.782516552,-0.033910594,-0.001823609,-0.023038426,-0.258442552,0.003956111,-0.007594924,-0.059236292,0.030830405,-0.140416867,-0.7729503670000001,-1.8251260630000001,-1.739907041,1.115358893,1.328920202,-8.365798621,-10.89027876,-9.74103804,-6.736983955,-7.742383437999999,-6.718308914,-6.7472355639999995,-3.013295662,-1456.15720416978 -4719,4719,N272K,-0.053729834000000004,0.027542814,-0.8989110579999999,-1.700728051,-2.7899761439999997,-0.033025672,-0.064105402,-0.043354265999999995,-0.158506084,0.046047448,0.009038179,-0.500343666,-1.29747845,-1.678952705,-1.7225033969999999,-2.331598096,-3.248354192,1.750991385,0.862109468,-8.066130597,-10.49394318,-6.767904617,-8.511230942000001,-8.754548576,-5.803025665,-6.69223581,-1.21357071,-1436.5491560832597 -4720,4720,N272M,0.018310811,0.089819225,-0.398696265,-1.692564294,-2.471224247,0.037609638,0.060640152,-0.02401853,-0.386174189,0.099011007,0.080627443,-0.119710496,-0.677682033,-1.563458836,-1.8216697519999998,-2.174711542,-2.7677369510000003,1.228820794,0.756571427,-12.65838694,-15.57863517,-12.26107841,-14.186439000000002,-8.241037299999999,-13.0247448,-8.516267323,-2.799053672,-1440.2993037053384 -4721,4721,N272L,-0.045992358,0.00707696,-1.1341726140000001,-1.9886578209999999,-2.585728822,0.047406465999999994,-0.010555025,-0.08142969,-0.134487495,0.028440322999999997,-0.014286403,-0.811309011,-1.457036217,-1.8298648380000002,-2.147450803,-2.378969637,-2.792488006,2.5670800430000003,1.312241153,-12.00424889,-14.75264967,-11.47689108,-13.41644108,-9.604746033,-10.77051659,-7.727594986000001,-2.68970763,-1432.5098403766751 -4722,4722,N272Q,-0.021183942,0.007917307,-0.003577385,-0.146648213,-1.972910607,-0.00177953,-0.0022943489999999998,-0.040073535,0.037788561,0.040609966000000004,-0.024775352,-0.00741531,0.000260541,0.03210432,-0.325400746,-1.906069155,-2.039752058,0.7711728840000001,1.304565502,-7.983628147999999,-11.43663958,-6.690371132,-7.491059898,-6.250054497000001,-8.050015633,-6.202955085,-1.394818348,-1447.2635659417138 -4723,4723,N272P,-0.004011905,-0.28622861,-1.515232467,-2.0454084740000003,-2.7188121639999996,0.003552744,0.016703895,-0.024727705,0.10473535099999999,-0.046707532999999996,-0.525749687,-1.511168549,-1.519296384,-1.926513935,-2.164303013,-2.529797711,-2.907826617,0.67957569,0.037030564,-10.15122138,-11.65572986,-11.56747823,-10.09458411,-9.287427719,-8.150886986,-6.998781227,-2.779802045,-1453.9963851692155 -4724,4724,N272S,-0.030252532999999998,0.006409692,-0.010635249,0.015454115,-0.34725384600000003,-0.009283106,-0.025415372000000002,-0.035089694,-0.10398038400000001,0.030051209,-0.017231825,-0.005042993,-0.016227505,0.043702635999999996,-0.012794406999999999,-0.2560418,-0.438465892,0.574596769,1.4552800590000001,-6.064795747000001,-8.025879478,-5.58520314,-5.269724586000001,-6.465253692999999,-4.977917839,-5.12417719,-1.665140482,-1445.7033265857026 -4725,4725,N272R,-0.002127541,0.034472437,-0.283097455,-1.6682196130000002,-2.616846506,0.005906766999999999,0.02528944,-0.029544521,-0.290199148,0.056258449,0.012686423999999998,-0.065492516,-0.500702393,-1.406960917,-1.929478309,-2.263726291,-2.96996672,1.141535476,1.839582957,-9.662847717,-12.27937914,-11.24554509,-9.174606445,-9.177989426,-6.436718491000001,-6.549501493999999,-1.1647682129999999,-1421.6852135909721 -4726,4726,N272T,0.011714433,0.023926204,0.023053279,0.040536066,-0.465793446,-0.04744578,0.013014786,0.010414079,-0.092754053,0.039889186,0.007963221,0.018384798,0.027721759,0.044706097,0.036366035,-0.365006891,-0.56658,1.894592864,1.422241265,-8.943041521,-10.66430339,-8.499652092,-8.35925164,-8.629180397,-8.562820084,-7.563626579,-2.022385018,-1445.108299551066 -4727,4727,N272W,-0.05497461,-0.333984235,-1.8497057069999998,-2.3175368869999997,-2.795166843,0.007073101,-0.036185193,-0.073764027,-0.158506084,-0.08006738099999999,-0.587901088,-1.830267801,-1.869143613,-1.9927302040000001,-2.64234357,-2.302952914,-3.2873807719999997,2.462272951,1.0421756070000001,-12.0264918,-15.25028069,-12.42730246,-10.732796400000002,-9.337172928,-12.38490652,-8.728449888,-2.860228893,-1448.1344704297371 -4728,4728,N272V,-0.006610544,-0.00452383,-1.7800000000000002e-05,-1.210801525,-2.225302873,0.012013821000000001,0.023622985,-0.036844072,-0.196294645,0.028785686,-0.037833345,-0.026556523,0.026520982000000002,-0.771736373,-1.649866676,-2.026441755,-2.42416399,3.881750222,2.131921798,-12.23092758,-13.89471132,-15.56721265,-11.65771252,-9.84912104,-10.18588039,-7.772656755,-2.3576785119999997,-1439.0903445417061 -4729,4729,N272Y,-0.019510772,-0.069067065,-1.26830666,-2.0422774180000003,-2.942456395,0.041712855,0.028565985,-0.067587528,-0.298956987,0.013754116,-0.151888246,-1.154319565,-1.382293755,-2.025971137,-2.058583699,-2.482321883,-3.4025909060000004,1.362315305,2.531412538,-10.42520367,-12.76730959,-11.274289900000001,-8.639717743,-9.128848457,-10.31585264,-8.021267678,-2.708028739,-1449.8078627204522 -4730,4730,R273A,0.018505737,0.004479534,0.029985123,0.024175599,-0.007123175,-0.009816535999999999,0.012780626000000002,0.024230847000000003,0.02162181,-0.017019972,0.025979039,-0.022359471000000002,0.082329716,0.013357025,0.034994172999999996,-0.049828471,0.035582121,1.477318857,2.287625184,-0.324098868,0.133507607,-1.223462738,-0.319495857,0.11903949,-0.33008284,-0.35388106700000005,1.096669928,-1469.555019106716 -4731,4731,R273C,-0.026973725,0.027862282999999998,0.007180046999999999,0.016976524,-0.193968327,-0.010930371000000001,-0.055475495,0.0015280460000000001,-0.020744321,0.056686897,-0.0009623310000000001,-0.014319152,0.028679245,0.016310856999999998,0.01764219,-0.15095692800000002,-0.236979726,1.425311276,2.2410107999999997,-7.167574728,-7.076200127000001,-7.268829887000001,-7.843083702,-7.002174461,-6.647585464,-6.742537716,-5.801072034,-1469.7324852785096 -4732,4732,R273E,0.042509079000000005,0.04073606,-0.001431225,0.059097727,-0.0075426830000000005,-0.086908501,0.057661653,0.027356505,-0.027247856,0.088035565,-0.006563445,-0.028627429,0.025764979,0.090895074,0.02730038,0.025483111,-0.040568476,1.26322028,2.092326537,-1.247453065,-1.895240761,-1.791038689,-0.8741535109999999,-0.46116127799999995,-1.215671089,-1.4617967180000002,0.13816734,-1462.1327528432012 -4733,4733,R273D,0.062110096,-0.04360097,0.038240759,0.09257050900000001,-0.13876223199999999,-0.004715745,0.08336307700000001,0.040857115,-0.02243195,-0.062786352,-0.024415588,-0.013229329,0.089710847,0.037521763,0.147619255,-0.165095325,-0.112429139,1.18809423,2.79001725,-3.3930288589999997,-4.000329651,-3.473650543,-3.2418055110000004,-2.8181932069999998,-3.431165382,-2.414712372,-0.524166577,-1461.5027516707778 -4734,4734,R273G,0.018874513,0.00628894,-0.011514123000000001,-0.002030531,-0.083012415,-0.04991393,0.01869116,0.019057866,-0.0005230359999999999,-0.00063772,0.013215600000000001,-0.037623271,0.014595026,0.015567673,-0.019628735,-0.096377486,-0.069647343,1.485328664,2.4096806269999997,-3.013665625,-2.946638252,-3.409270218,-3.0519548110000003,-2.805581291,-2.854883553,-2.7157689830000002,-1.490549708,-1470.440898080822 -4735,4735,R273F,0.06396334099999999,0.014845793000000001,0.00685101,0.018896259,-0.126650445,-0.128652891,0.074732887,0.053193794,0.05721176099999999,0.015036241,0.014655345,-0.014319152,0.028021171,-0.012578708999999999,0.050371227000000005,-0.153208431,-0.10009245900000001,1.4412421309999999,2.390395704,-7.603258415,-7.076874312999999,-8.154137032000001,-9.055799377,-7.987339874,-5.742141479,-5.469725324,-4.472452335,-1467.3390922467224 -4736,4736,R273I,0.111033003,0.033559082000000004,0.053260870999999994,0.105435155,-0.016893345,-0.083017406,0.095037074,0.12702893099999998,-0.03444175,-0.030721249,0.09783941199999999,-0.071357653,0.177879395,0.071742177,0.139128132,-0.10609863800000001,0.072311949,1.220591271,2.379905549,-5.222427307,-5.197386101,-5.9456239779999995,-5.745323364,-3.87235141,-5.3514516830000005,-4.220002071000001,-2.664720253,-1471.3394863023423 -4737,4737,R273H,0.034104136,-0.04540119,-0.023436111000000003,-0.031029955,-0.019283043,-0.068105809,0.042492322,0.025715949,0.015712854,-0.072489785,-0.018312593999999998,-0.091393001,0.04452078,-0.08416277300000001,0.022102864,-0.083069237,0.044503151,1.274568405,2.2671895280000003,-3.642267139,-4.396216843,-3.6486232760000004,-3.979755135,-3.408601692,-2.778138748,-4.111279923000001,-2.232376773,-1461.7366046858951 -4738,4738,R273K,-0.018940675,0.021323883,0.0030958340000000004,0.051887744000000006,-0.048172532000000004,-0.018099133,-0.019516814,-0.018364535,-0.060835754000000006,0.08374131,-0.041093545,-0.034810627999999996,0.041002296,0.047902039,0.055873448,-0.059058633,-0.037286431,1.280462821,2.298336825,0.13892231900000002,0.42226040600000003,0.19859412399999998,-0.627759903,0.448933121,0.252583847,-0.0760093,0.00500682,-1465.3256033896469 -4739,4739,R273M,0.000195402,-0.034678861,-0.018451323999999998,-0.007985131999999999,-0.104095374,0.015127633,0.017280653,-0.01688985,-0.11113136800000001,-0.025329743,-0.044027977999999995,-0.0045461370000000004,-0.032356511,-0.0015833239999999999,-0.014386939,-0.103163636,-0.10502711199999999,1.339676866,2.420110777,-4.794306494,-5.157402779,-5.705244652,-5.129123802,-3.702047157,-4.277714081,-4.870563985,-3.23376571,-1470.016765005421 -4740,4740,R273L,0.04899171099999999,0.031334926,0.01400842,0.025461197,-0.034706069,-0.053244398,0.052857642999999996,0.045125779000000005,-0.011952846999999999,0.025880822,0.03678903,-0.049202181,0.07721902,-0.006813653,0.057736046,-0.080318666,0.010906528,1.220664437,2.171555293,-3.5382469480000003,-4.324511459,-4.415751724,-3.3844700089999997,-2.182647354,-3.383854195,-2.76941412,-1.4160594219999998,-1467.9514315035194 -4741,4741,R273N,0.035933452000000005,-0.0010236380000000001,-0.061501362000000004,0.003042483,-0.062109925,-0.022501899,0.061850529,0.010016375,-0.023322237000000003,-0.028218373999999997,0.026171099,-0.096436891,-0.026565832,0.00038626800000000005,0.005698697,-0.079105995,-0.045113855,3.342225137,1.9434087919999998,-3.8821213410000004,-4.422082245,-2.714630783,-4.93126548,-4.3194236980000005,-3.023204498,-3.904892764,-1.8090126430000002,-1461.5854563331231 -4742,4742,R273Q,0.067728353,0.018543393000000002,0.016264485,0.028926992999999998,0.0042988309999999995,-0.110088715,0.045506381,0.089950325,0.030393712000000003,0.015333195,0.02175359,0.011506787,0.021022183,0.044148915999999996,0.01370507,0.016085246,-0.007487585,2.9223725469999997,1.92541614,-0.342386234,-0.966286034,-1.031754082,-0.14914159400000002,0.530850739,-0.095600197,-1.7954531459999998,-0.432433112,-1466.2720641945489 -4743,4743,R273P,-0.026607738,-0.068729342,-1.2892827340000002,-1.9997875019999998,-2.463472371,-0.06599882,-0.016948346,-0.03626713,-0.005614903,0.006094077,-0.14355276,-1.0273674940000002,-1.551197973,-1.930384197,-2.069190807,-2.2211054409999997,-2.705839301,1.149456302,2.659380698,-3.67158058,-4.099583748,-4.729502495,-3.982655914,-4.298177094,-1.24798365,-3.1647398389999997,-0.987750462,-1468.538058558479 -4744,4744,R273S,0.035589459,0.014387298,0.033143757999999995,0.030517715,-0.030727435,-0.033809835,0.041534517,0.029644401,0.018593112,0.03647879,-0.007704195,0.002953752,0.063333763,0.027577486000000002,0.033457943999999996,-0.039289698,-0.022165171,1.286724075,2.519362906,-2.617100127,-2.480164375,-2.89774894,-3.0819883189999997,-2.900401825,-1.725197174,-2.8814062469999997,-1.251553269,-1466.0857541053556 -4745,4745,R273T,0.048148572,0.006090244,0.035820394,0.038846351,-0.017076403,-0.060537325,0.055513577,0.040783567,0.070950859,-0.0035442290000000003,0.015724716,-0.025905407999999998,0.097546196,0.02552207,0.052170630999999995,-0.03004566,-0.004107145,1.243379167,2.524836693,-2.322740489,-1.462617592,-3.38855645,-3.132381645,-2.608725479,-1.02142128,-2.270420623,-1.221977713,-1469.0925543205813 -4746,4746,R273W,-0.010066024,-0.017464948,-0.021480287999999997,-0.04342646,-0.143334305,-0.06201426,-0.015919642,-0.004212405,-0.009055515,-0.028625654,-0.006304242,-0.096827251,0.053866675,-0.052361616,-0.034491304,-0.183777352,-0.10289125699999999,1.58062497,2.248609267,-7.0535316539999995,-7.135460411,-7.032980736,-7.772044701,-7.275353966,-6.051818459,-5.658644195,-4.516170188,-1469.917066379916 -4747,4747,R273V,0.027985072000000003,-0.01703843,-0.020673321,0.01846637,-0.039767452,-0.047406937,0.037279353,0.018690791000000002,0.047119062,-0.041464767,0.007387908,-0.057855183,0.016508542,-0.000282391,0.03721513,-0.08940306699999999,0.009868164,1.4643506869999998,2.4719636019999998,-4.202275642,-3.872183746,-5.012561462,-4.823983635,-3.63109774,-3.671551628,-4.071774254,-1.526447816,-1473.9788592476398 -4748,4748,R273Y,0.037664913,0.025705977,-0.006541016,0.030847416000000003,-0.042931939,-0.008036299,0.06853355,0.0067962759999999995,-0.011712648999999999,0.003082427,0.048329526,-0.08158728400000001,0.068505253,-0.04050139,0.10219622199999999,-0.12376644699999999,0.037902569,1.4301309869999999,2.273058002,-7.246611481,-7.059349777,-7.984315125,-8.628974342000001,-7.557939987,-5.002478172,-5.311325,-4.2474545610000005,-1461.663915839512 -4749,4749,Q274A,-0.02754578,0.029658929,-0.021099838,-0.013000835,0.021095374,-0.015979021,-0.057881992,0.0027904329999999997,-0.008547971,0.042513639000000006,0.016804219,-0.023122076000000002,-0.019077599,0.034365293,-0.060366962,0.008090606,0.034100141,1.190771732,2.752532561,-1.102549677,-0.692565842,-1.990490845,-1.059884201,-0.953784889,-0.816022606,-2.101624955,3.5954671119999997,-1464.6875839205459 -4750,4750,Q274C,-0.034845223,-0.0028397970000000002,-0.018970993999999998,-0.049068637000000005,0.0025160210000000002,-0.06502609599999999,-0.033543516,-0.03614693,0.06762066900000001,-0.013867186,0.008187593,-0.029943453,-0.007998534,-0.005666043000000001,-0.092471231,-0.046388114,0.051420155999999995,1.24347922,2.4438950569999998,-5.934735515,-6.250626595,-7.493432808,-5.16841536,-5.218411995,-5.542790817,-4.720510291,-0.7034468220000001,-1462.690112540964 -4751,4751,Q274E,-0.08979142300000001,-0.002434464,-0.031554087,-0.025829117999999998,-0.05505396,-0.020936808,-0.081885061,-0.097697785,-0.025490468999999998,0.019321256999999998,-0.024190184,-0.003050122,-0.060058052,0.045272407,-0.096930642,-0.002373705,-0.10773421400000001,1.228452329,2.731102576,-3.4557889189999997,-2.9013688510000004,-4.3528713230000005,-3.208870003,-3.2530708010000002,-3.562763618,-4.616312925,-0.82296096,-1459.9142029569484 -4752,4752,Q274D,-0.057334305999999995,-0.014953251,-0.025441746,-0.932921418,-1.9017767319999999,-0.027662326,-0.024317016,-0.09035159599999999,0.028291042000000002,0.000484625,-0.030391127,-0.005872212,-0.04501128,-0.291156263,-1.5746865730000001,-1.897705275,-1.905848189,1.343076584,1.346752705,-6.304823141,-6.880741699,-6.949713211000001,-5.481692154,-6.33057518,-5.881393462999999,-5.665175141000001,-1.331591637,-1456.9507824014872 -4753,4753,Q274G,-0.07327827099999999,0.008315531,-0.038020694,-0.026330595,-0.353408171,-0.0030403759999999996,-0.047722342,-0.0988342,0.034946225,0.002483058,0.014148003000000001,-0.03166225,-0.044379137,0.008119975,-0.060781165,-0.256378787,-0.45043755399999996,1.201104751,1.865490809,-5.492237659,-5.051880699,-5.329519737,-6.606426476,-4.6330928039999995,-5.840268578,-4.229653161,-0.8107271909999999,-1464.2839270508848 -4754,4754,Q274F,-0.10023003300000001,-0.081638334,-0.056645376,-0.117635813,-0.114884101,-0.0022561670000000003,-0.082589833,-0.117870233,0.016611891,-0.083907022,-0.079369645,-0.040424062999999996,-0.072866689,-0.081685562,-0.153586063,-0.156704972,-0.07306323,1.5867351440000002,2.344134907,-5.33403903,-7.459368454,-5.960101906,-3.904954262,-4.704722191,-4.64104834,-4.310036051,1.7293664930000001,-1455.583072161302 -4755,4755,Q274I,-0.056472466,-0.028563112999999998,-0.046709266,-0.041060762,-0.035070981,-0.041459156000000004,-0.07410828400000001,-0.038836648,-0.037166679,-0.01021364,-0.046912585,-0.005384877,-0.088033654,0.064419978,-0.146541501,-0.040970252,-0.029171709,1.2473635490000001,2.50703257,-4.874457727,-5.506892487000001,-5.723455872000001,-4.735490073999999,-3.6218655010000003,-4.784584702,-3.223416532,2.962734471,-1458.6869096364826 -4756,4756,Q274H,-0.030290297,-0.019757025,-0.026608395,-0.042476731,0.015989086,-0.054399293,-0.045579048,-0.015001546000000001,0.044899594,-0.007341955,-0.032172095,-0.009450763000000001,-0.043766026,0.009391987,-0.09434544800000001,-0.011627443000000001,0.043605615,1.3226672940000002,2.617897504,-1.999197383,-1.937262024,-2.233154129,-1.6519496,-2.210432175,-1.9631889880000002,-2.8312708860000004,-0.97008381,-1458.448078012094 -4757,4757,Q274K,-0.097588815,-0.005958817,-0.049797234,-0.07042327,-0.067261017,0.011097933999999999,-0.081277432,-0.113900197,0.045364798,-0.052152205,0.040234571000000004,-0.011845231000000001,-0.087749237,-0.014451801,-0.126394739,-0.039445789,-0.095076245,1.371620235,2.5098517890000003,-3.473255493,-3.9970622710000003,-3.0793628460000004,-3.6209071880000003,-3.590927505,-3.078017654,-3.671408533,0.023799141,-1456.9929970847443 -4758,4758,Q274M,0.00298749,-0.001099673,-0.024342928,-0.030054905,-0.0016282929999999998,-0.036004707000000004,0.010584988,-0.004610008,0.089567635,0.015477611,-0.017676956,-0.011774894,-0.036910961,0.008115453,-0.068225263,-0.027887067,0.024630481,1.197209823,2.556279004,-5.265051324,-7.036064339,-4.402873131000001,-6.130845527999999,-3.379127281,-5.376346344,-4.261379713,1.4446319230000002,-1460.741607114207 -4759,4759,Q274L,-0.046053971,0.004714327,-0.037633357,-0.036858275,0.004304036,-0.011092435,-0.053040132999999996,-0.039067809,0.038772548999999996,0.021537887999999998,-0.012109233999999998,-0.016169186000000002,-0.059097527999999996,0.020245785,-0.093962335,-0.005488021,0.014096092,1.190206942,2.541524194,-3.843356313,-4.811871841,-4.614285011000001,-4.275255737,-2.509185249,-3.006183723,-2.1226470109999998,3.930502995,-1459.5702432333492 -4760,4760,Q274N,-0.02165357,0.036975346,0.012456123000000001,0.0013372870000000002,-0.138912435,-0.071280642,-0.003242977,-0.040064163,0.021133337000000002,0.010094737,0.063855954,0.013094888999999998,0.011817356999999999,0.030782933,-0.028108359,-0.15591688,-0.12190798900000001,1.365674417,2.205348155,-5.397968929,-6.603283012,-5.025456116,-5.368490746,-5.779229667999999,-4.213385101,-6.077844621000001,-0.9418265659999999,-1459.6626754016615 -4761,4761,Q274P,-0.024265742000000003,-0.017481211,-0.04224768,-0.609354677,-1.761989201,-0.049787232,-0.042886424000000006,-0.005645059,0.027540737000000003,-0.013510811000000001,-0.02145161,-0.032725221,-0.051770138,-0.13854423300000002,-1.08016512,-1.783378427,-1.740599974,1.0374318340000002,1.327565316,-6.4231833389999995,-6.503982506,-8.183305969,-6.722671806,-5.413595261,-5.292361153,-4.452036092,-0.189699885,-1462.4062385517173 -4762,4762,Q274S,-0.018790166,-0.001162914,-0.035876873999999996,-0.029355452999999997,-0.036141202000000004,-0.021899362000000002,-0.005679948000000001,-0.031900383,0.005164422,0.0072364809999999995,-0.009562308,-0.019284496,-0.052469252,0.017098546000000003,-0.075809452,-0.045265220999999994,-0.027017182999999997,1.312288508,2.527666673,-5.320170287,-5.967720619,-5.264715027,-5.101610611,-5.610961014,-4.655844162,-4.943891226,0.208434426,-1464.8884019302204 -4763,4763,Q274R,-0.032040683,0.0035277579999999998,-0.01055972,-0.034706796,-0.067524796,-0.038870853,-0.027184497000000002,-0.036896868,0.05452811900000001,-0.008997674,0.01605319,-0.011620107,-0.009499332,-0.008973753000000001,-0.060439837999999996,-0.08738589199999999,-0.047663699000000004,1.32176643,2.289655704,-3.29577074,-3.9028213810000003,-4.443630898,-3.174662544,-2.990900902,-1.966837975,-4.849690658,0.8186029340000001,-1456.2164025725797 -4764,4764,Q274T,-0.0071633090000000005,0.00249145,-0.041306344,-0.044343234,-0.039528661,-0.015292961,-0.0076025419999999995,-0.006724075,0.033595276,-0.020531483,0.025514382000000002,-0.030299127999999998,-0.052313559,-0.042113233,-0.046573235,-0.076353325,-0.0027039959999999997,1.3220483570000001,2.325197464,-4.028962235,-4.355695297,-3.95744902,-3.95602137,-3.456609756,-4.419035728,-2.975386199,2.408775785,-1464.946604322642 -4765,4765,Q274W,-0.036701978999999996,0.010252566999999999,-0.028438751,-0.034740095,0.022395673999999997,-0.017440202,-0.038611406,-0.034792552000000004,0.027190982000000002,-0.002678588,0.023183722,-0.040088765,-0.016788736999999998,-0.031673900000000005,-0.03780629,-0.009562859,0.054354207,1.338230023,2.622232115,-6.145883347000001,-5.344316948,-9.670859161000001,-5.126168312,-5.833386947999999,-4.754685364,-4.220553165,-0.38467381100000003,-1455.1870296108536 -4766,4766,Q274V,-0.012650797,0.002679929,-0.060767977,-0.03978115,0.017103224,0.00667329,-0.020314443999999997,-0.004987149000000001,0.032997487,-0.010302667,0.015662525,-0.067999763,-0.053536191,-0.006491584,-0.073070715,-0.022713142000000002,0.05691959,1.424047875,2.571789416,-3.0260135989999997,-3.444137436,-3.467461472,-3.188999763,-2.6041841740000002,-2.425285149,-2.58519043,3.5400173280000002,-1462.2014648830518 -4767,4767,Q274Y,0.031832519,-0.05278257,-0.009744519,-0.011870995,-0.092507326,-0.060205065999999995,0.045408826,0.018256212,-0.014248756999999999,-0.12553566800000002,0.019970528,-0.09215713199999999,0.072668095,-0.029822186,0.0060801959999999995,-0.131773026,-0.053241625,1.396540044,2.246416119,-3.919916275,-3.779225685,-4.308113823,-3.395153397,-4.385569664,-3.7315188060000004,-4.778929562,0.36715087,-1455.680686709471 -4768,4768,I275A,-5.5700000000000005e-05,-0.001879209,-0.907259057,-1.897835977,-2.439738277,-0.018365913,-0.000172589,6.11e-05,0.037939416000000004,-0.005602735,0.001844318,-0.46669551600000003,-1.347822597,-1.7562533359999999,-2.039418618,-2.210942674,-2.66853388,2.926105798,1.749676944,-8.628404227,-5.871428986000001,-9.074587952,-13.91504097,-6.8009349210000005,-7.480028305,-6.08182364,-4.321669498,-1447.4440073352307 -4769,4769,I275C,0.001317929,0.010862874,0.06506297400000001,-0.81046375,-1.8161600709999999,-0.026790507999999998,0.007562131999999999,-0.0049262740000000005,0.065763425,0.023151353,-0.001425606,0.051474385,0.07865156200000001,-0.164941184,-1.455986316,-1.959578584,-1.672741558,1.046489202,1.3131823870000001,-11.61364077,-8.487767586,-13.36587415,-16.1395902,-9.143384575,-10.93158732,-7.360391935,-4.994998004,-1457.7885572621599 -4770,4770,I275E,-0.024310809,-0.8179078609999999,-1.858319974,-2.162027079,-2.747169622,-0.006516704,0.028864921,-0.07748653900000001,0.102833455,-0.5269196979999999,-1.108896023,-1.843609066,-1.873030881,-1.886422176,-2.437631982,-2.517202773,-2.97713647,3.436198511,1.6061418280000002,-12.68330055,-10.15234972,-12.66823276,-19.09430688,-10.05683628,-11.44477711,-8.028282977,-6.187012801,-1463.1253913436085 -4771,4771,I275D,-0.027642266000000002,-1.3493099119999998,-2.02553685,-1.876731713,-2.93899551,0.020008385,0.01238098,-0.067665512,0.059753875,-1.345933569,-1.352686255,-2.4432629869999998,-1.6078107130000001,-1.963197352,-1.7902660730000002,-2.718916686,-3.1590743339999996,0.036634672,-0.827690447,-14.49114027,-11.14731986,-15.0238857,-21.51391459,-11.50844238,-13.26213882,-8.649820737999999,-7.07168951,-1462.70039397059 -4772,4772,I275G,0.007728294,-0.690030128,-1.9168383219999998,-2.021057465,-2.711967313,-0.016715279,0.018808524,-0.003351936,0.064603335,-0.39183775600000004,-0.988222499,-1.9818219369999999,-1.851854706,-1.991842534,-2.050272395,-2.642826517,-2.781108108,1.172262815,-0.116360483,-12.18518138,-9.228764404,-13.14955711,-18.47198851,-9.461589577,-10.61400731,-7.234858163999999,-4.6340088680000004,-1456.370048569981 -4773,4773,I275F,-0.022057005,0.046488095,0.071046295,0.133818796,0.08968222,-0.09637305199999999,-0.037085979,-0.007028031,0.042079969,0.119099186,-0.026122997000000002,0.19316590600000003,-0.051073317,0.192317297,0.07532029400000001,0.16537878,0.01398566,1.031816043,3.1957912910000004,-6.495315529,-3.968827751,-6.058925987,-7.151225693,-8.100083076,-7.197515137000001,-4.969172221,-2.749201696,-1464.896873023361 -4774,4774,I275H,-0.010020651,-0.119131267,-1.553084219,-2.044714542,-2.541811455,-0.018157193000000002,0.023593887,-0.043635189000000005,0.063663851,0.005844477,-0.24410701,-1.242420715,-1.8637477219999998,-1.9286865009999998,-2.160742583,-2.2584371030000003,-2.825185807,2.972801913,1.507527499,-10.242102599999999,-4.681064903,-10.04069859,-18.11421626,-8.109189835,-10.26534341,-4.9856331780000005,-3.099209262,-1470.8049943870865 -4775,4775,I275K,-0.091123242,-1.393714747,-2.463404273,-2.3207163630000003,-2.755343908,-0.05504843400000001,-0.09327105599999999,-0.088975427,0.063614058,-1.299840845,-1.487588649,-1.950012232,-2.976796313,-1.8959153290000001,-2.745517397,-2.526695927,-2.983991889,4.002667298,1.808555359,-14.08305897,-11.37246316,-14.46673823,-20.33527316,-10.65150823,-13.58931207,-8.877430577,-7.530862831,-1462.939138656482 -4776,4776,I275M,0.005011609,0.01145538,0.008364801,0.068967406,-0.220181281,-0.060829522999999996,-0.020612242,0.030635459,0.03674778,0.02014419,0.0027665690000000004,0.0398076,-0.023077999,0.083741608,0.054193204,-0.14644568800000002,-0.293916874,1.396122805,2.24667422,-5.816622015,-4.9127257460000004,-6.344098686000001,-7.705639113999999,-5.591704826,-4.528941704,-5.161657537,-1.90397913,-1463.0834939801134 -4777,4777,I275L,0.056018095,0.049227169,0.089926485,0.112805758,-0.126616109,-0.05108165,0.057994493,0.05404169599999999,0.074081672,0.030150813,0.068303525,0.125666109,0.05418686,0.117795974,0.107815541,-0.077256054,-0.175976164,1.271819585,2.468221541,-4.506190892,-3.042512505,-5.864920906,-5.910533096,-4.204286324,-3.50870163,-4.292800442,-1.17338686,-1460.4890614734031 -4778,4778,I275N,-0.071911453,-0.935497664,-2.0167078419999998,-1.8914009859999998,-2.476543529,0.030376371,-0.00039591699999999997,-0.143426988,0.10927174199999999,-0.578055203,-1.292940125,-2.201354444,-1.83206124,-1.721288809,-2.0615131630000003,-1.999886888,-2.9532001689999996,1.4268040569999998,-0.070778581,-13.18685235,-9.91385199,-15.78229115,-19.18212263,-10.20297526,-10.85302074,-7.7085683629999995,-5.5627872929999995,-1466.1178903891705 -4779,4779,I275Q,0.013188595,-0.723883319,-2.151574516,-2.412943844,-2.642484156,0.02191641,0.076791279,-0.050414089,0.09288252400000001,-0.328658888,-1.119107749,-2.393803623,-1.9093454090000002,-1.6706999390000001,-3.155187748,-2.192336067,-3.092632244,0.160303953,-0.47284944100000004,-12.23651223,-8.633685295,-12.57918719,-20.67984286,-8.843507675,-10.44633812,-6.903414712000001,-5.287203797,-1465.5931616257876 -4780,4780,I275P,0.022229712999999998,-1.405739811,-1.9221664459999999,-2.097080973,-3.0192967260000003,-0.010203057,0.041431813,0.0030276120000000003,0.08977777099999999,-1.311993782,-1.499485839,-1.944436403,-1.899896489,-1.93289185,-2.261270096,-2.77293207,-3.265661382,-0.031497897000000004,-0.792920582,-13.22762707,-11.0939675,-13.88031013,-17.90375451,-11.07412482,-12.18597839,-9.172198157999999,-8.156429405,-1471.8829362187535 -4781,4781,I275S,0.031733741,-0.568478224,-1.846610425,-2.225655363,-2.732310421,-0.017603403,0.046700369000000005,0.016767113,0.060075475,-0.296687048,-0.8402693990000001,-1.912359458,-1.7808613919999998,-2.034353814,-2.4169569109999998,-2.5304358380000003,-2.9341850039999997,1.090730298,-0.061691949,-11.79798542,-8.561685974,-13.64867404,-16.68234362,-9.443138817000001,-10.65408466,-7.81536612,-6.119520047000001,-1462.1829265919514 -4782,4782,I275R,0.016134171,-1.3516428809999999,-1.860747491,-2.17145896,-2.93873551,-0.0035862529999999998,0.025825478,0.006442864,0.044545941,-1.337358452,-1.36592731,-1.897353209,-1.824141772,-2.182074862,-2.160843058,-2.53202885,-3.3454421689999996,0.176498264,-0.797088182,-15.21142708,-10.38273331,-15.54736574,-24.54202978,-11.6608839,-13.924122699999998,-9.663760142000001,-9.382515756,-1459.178807482589 -4783,4783,I275T,0.0013983079999999998,0.019620932,-0.01224561,-1.429135768,-2.361641829,0.005331054,0.020080305,-0.01728369,0.047477585,0.017967398,0.021274466000000002,0.059026498,-0.083517718,-1.129714466,-1.728557069,-2.172675511,-2.5506081469999997,2.16250571,1.437562065,-10.39823908,-7.162806357999999,-11.00073662,-15.66569762,-8.241904968,-9.920049828,-7.2065983760000005,-4.165364197,-1461.7698886585422 -4784,4784,I275W,0.001324006,0.06530680900000001,-0.727406672,-2.138034597,-2.362077217,-0.024013261,-0.001442086,0.004090097,0.066214352,0.096664648,0.03394897,-0.282119518,-1.172693826,-1.661238384,-2.61483081,-2.229871074,-2.49428336,1.0564675609999998,0.719535757,-13.23391374,-10.38550916,-13.62061644,-16.68403116,-12.36211575,-13.11729621,-9.206607206000001,-8.422806375,-1456.6259617763571 -4785,4785,I275V,0.049367068,0.025095562000000002,0.074328659,0.057454615,-0.044125186,-0.011119292,0.041209567999999995,0.057524567,0.057081464000000005,-0.003575052,0.053766175,0.070909654,0.07774766400000001,0.026311362,0.08859786800000001,-0.028520841,-0.059729530999999995,1.22798405,2.501998941,-3.5878606960000003,-3.277573555,-4.585765793,-3.631633484,-3.7211632389999996,-2.723167412,-3.268839807,-1.669670789,-1461.4035538421012 -4786,4786,I275Y,-0.011969448,0.005181589,0.015867115,-0.10169401,-1.6145716559999999,-0.10473864,-0.0041458929999999995,-0.019793002,0.082529717,0.00209299,0.008270188000000001,0.002341216,0.029393014,0.134580382,-0.33796840200000006,-1.501432742,-1.72771057,0.613126077,1.314897246,-10.33422766,-5.585998665,-10.01471344,-13.87063116,-10.76400658,-11.43578845,-6.8057693079999995,-5.794613976,-1467.2796009518206 -4787,4787,A276C,-0.003691325,-0.007567267,-0.034851925,-0.013809043,-0.299150607,-0.01239783,0.006958269,-0.014340918999999999,-0.002813853,0.0029453540000000003,-0.018079888,-0.059616487,-0.010087361999999999,-0.046716463,0.019098377,-0.20174115899999998,-0.396560055,1.3951510409999999,2.09388478,-8.902840063,-9.479266327000001,-7.659302391000001,-8.794620659,-9.264240295,-9.316770645,-7.4594607129999995,-6.985155437,-1462.60810379358 -4788,4788,A276E,0.025743792999999997,-0.018260546000000002,-0.008491644,-0.056446055999999994,-0.779277688,-0.094396934,0.012542413999999998,0.038945171,0.059615667000000004,0.001391735,-0.037912826000000004,-0.059745165999999995,0.042761879,-0.08365637599999999,-0.029235736000000002,-0.666112974,-0.892442402,1.22661298,1.577312765,-5.658824867000001,-5.103459999,-5.0052481,-5.711222237,-5.203573029,-7.270620972000001,-4.807635564,-3.873384123,-1455.0821615359746 -4789,4789,A276D,0.020969803999999998,-0.022287445,-0.026263375,-0.107828254,-1.550481094,-0.081249362,0.015420287,0.026519321000000002,0.062400544,-0.014465132,-0.030109757999999997,-0.067107908,0.014581159,-0.053294243,-0.162362264,-1.76720407,-1.3337581170000001,0.6965749940000001,1.307969311,-8.536827275,-7.963535721,-6.846053658,-9.227985634,-8.780190597999999,-9.866370766000001,-7.505735726,-7.043619969,-1456.0714586321265 -4790,4790,A276G,0.015998185,-0.004739643,-0.0009911380000000001,-0.002452283,-0.344260545,-0.08267954799999999,-0.006600998,0.038597367,0.009483158,0.017718156000000002,-0.027197441,0.00971477,-0.011697046000000001,0.000716755,-0.00562132,-0.25409208,-0.434429009,1.344671111,1.996269239,-6.677811031,-8.839652237000001,-4.319663765,-6.9713041229999995,-6.513882324,-6.744552704,-4.738435478,-1.6205948890000001,-1466.9381624702364 -4791,4791,A276F,-0.00579526,0.034680023,-0.010399528,0.010663297,-0.088089711,-0.038445528,-0.016242236,0.004651716,0.014163051000000001,0.067633149,0.0017268960000000001,-0.013003256999999999,-0.007795799,0.006005944,0.015320648999999999,-0.083169194,-0.09301022800000001,1.475690292,2.479203001,-10.39051915,-11.30129021,-8.536359917,-10.83515689,-10.43867031,-10.84111842,-8.262831524,-7.646493721000001,-1455.509229469113 -4792,4792,A276I,-0.029396546000000003,-0.047192387,-0.074074485,-0.018130476,-1.478838915,-0.024612554,-0.013915247,-0.04487784400000001,0.045984764000000004,-0.08684204699999999,-0.007542726,-0.067926817,-0.080222153,-0.021264741,-0.014996211,-1.368582815,-1.589095014,1.06508445,1.3707267630000002,-6.875732956,-6.111890869,-5.488025177000001,-6.890523537000001,-7.909661697000001,-7.978563499,-5.669073616,-5.408171702000001,-1457.7878356175497 -4793,4793,A276H,0.066314329,0.004690145,0.021401821,0.013457665,-0.0692059,-0.067168164,0.05521446,0.077414198,0.031627947000000003,0.027535382999999997,-0.018155094,0.032276724,0.010526917,0.016713293,0.010202036,-0.042233709,-0.09617809,1.237293081,2.4271013619999997,-8.157183571000001,-8.388799323999999,-5.4963376539999995,-8.723345573,-8.534674171,-9.642761131,-6.118951145,-5.34031814,-1450.6016318826005 -4794,4794,A276K,0.038514898,0.052377365999999995,0.015396273,0.083233687,0.049749611,0.018550545,0.046471177999999995,0.030558617000000003,0.028856528,0.07043335,0.034321382000000004,0.055845725,-0.02505318,0.08930015300000001,0.07716722,-0.025887935,0.125387156,1.128780973,2.548236946,-5.238360808,-4.838803505,-4.47796521,-5.829384232000001,-6.313576744,-4.732074348,-4.7419756710000005,-3.927095871,-1454.021109547466 -4795,4795,A276M,0.006500373,-0.011872373,-0.028492106,-0.002898514,-0.06703507,-0.031781883999999996,-0.012582429,0.025583174,0.000227273,-0.014443791000000001,-0.009300955,-0.072805092,0.015820881000000002,0.025625726,-0.031422754,-0.08250716,-0.05156298,1.453696401,2.540214447,-8.852096407000001,-8.859414886,-7.561922485,-9.116454453,-9.937026428,-8.78566378,-7.581251891,-6.985155314,-1457.3267324590124 -4796,4796,A276L,-0.026929525,0.023245229,-0.002691207,0.015092895,-0.60293422,-0.040302901,-0.032863342000000004,-0.020995707000000002,0.018582493000000002,0.061921507,-0.015431048999999999,0.00567233,-0.011054743,0.01359942,0.016586369,-0.41986395200000004,-0.786004487,1.159694675,1.6881179240000002,-8.641094479,-8.296207008,-6.850186783,-8.505143593,-9.671116371,-9.882818642,-7.310066683,-6.501744154,-1455.1062142499723 -4797,4797,A276N,0.043803224,0.039714012,-0.003578527,0.031504597999999995,-0.616039405,-0.057705016,0.044111267,0.043495180999999994,0.056400547999999995,0.028926075,0.050501948,-0.001669805,-0.0054872490000000005,0.02189597,0.041113226,-0.483240069,-0.74883874,0.9346151840000001,1.5331278419999999,-5.949938057000001,-6.403395676000001,-4.080609993,-7.073294197,-5.843129684,-6.349260735,-5.295184735,-3.892485484,-1457.8893905095756 -4798,4798,A276Q,0.109645403,0.005176798,0.022556586,0.064583418,-0.052753796,-0.035765871,0.11078383800000001,0.10850696800000001,-0.039126135,-0.02549561,0.035849206,-0.074390716,0.11950388699999999,-0.008543919,0.137710754,-0.082898828,-0.022608762999999997,1.20113283,2.204479806,-5.2823442410000006,-5.346397568,-3.545718552,-5.531332977000001,-5.332157104,-6.656115005,-4.698797647,-2.5695604569999997,-1458.2458409033716 -4799,4799,A276P,-0.029075922,-0.48701323,-1.8587887019999998,-1.984420003,-2.550635631,-0.023978329,-0.028431151,-0.029720693,0.003570411,-0.178639369,-0.79538709,-1.803928334,-1.913649069,-1.965548515,-2.003291491,-2.493029112,-2.60824215,0.9537680909999999,-0.027403395,-7.298451497,-7.703163116,-4.954476936,-7.557997589,-7.4981450039999995,-8.778474838,-6.735959052,-4.341025581,-1467.7930722949095 -4800,4800,A276S,-0.012865521999999999,-0.013179221999999999,-0.039095185,0.004458084,-0.055652281,-0.025570238999999998,-0.032499169,0.006768125,0.050462402999999996,0.002448891,-0.028807334,-0.036569039,-0.041621331,0.004037329,0.004878839,-0.067147254,-0.044157308,1.227514043,2.331774979,-3.309900565,-4.604296677,-1.988797836,-3.3358695139999996,-3.3871080019999997,-3.2334307939999998,-3.514746058,-2.416510928,-1461.8047509947792 -4801,4801,A276R,-0.016676092,-0.0054798469999999995,-0.005058986,0.01800028,-0.022418982,-0.030124675,-0.033011009,-0.000341174,0.00981527,0.021385806,-0.032345499,-0.005686259,-0.0044317129999999995,0.009135644,0.026864915,-0.021828139,-0.023009825,1.385781746,2.661995835,-5.21939511,-5.943340881,-3.397115608,-4.55450222,-6.327174706,-5.874842133,-4.026266985,-2.0664148890000003,-1451.837118606083 -4802,4802,A276T,-0.025133078,-0.011782298,-0.052611671,-0.027806374,-0.6621733879999999,-0.096130542,-0.035941982000000004,-0.014324173,0.011344963999999999,0.006797724000000001,-0.030362319,-0.044357333,-0.060866009000000006,-0.016772423999999998,-0.038840322999999996,-0.48588193799999996,-0.8384648370000001,0.971463038,1.5428088290000002,-5.0808588210000005,-5.643151787000001,-3.6542101060000003,-5.228705902,-4.96430304,-5.913923271,-5.225824281,-4.423774723,-1460.3514387933537 -4803,4803,A276W,0.016703433,-0.018125741,-0.043425189,0.016847887,-0.9135135329999999,-0.124920766,-0.043672462,0.077079327,-0.006940261,-0.020962671999999998,-0.015288808999999999,-0.07517128,-0.011679098,-0.015837768999999998,0.049533542,-0.6806492259999999,-1.1463778390000001,0.904875215,1.4502244480000002,-11.20906292,-11.97157731,-9.099558417999999,-11.70535574,-11.44111526,-11.82770786,-9.062415357,-10.01779928,-1459.9960863869637 -4804,4804,A276V,-0.022864566,-0.001704977,-0.021373407999999997,0.024532795,-0.172800332,-0.09194837,-0.042436969000000005,-0.003292163,0.020686917,0.043150965,-0.046560919000000006,0.007104803000000001,-0.049851618,0.032108585,0.016957005,-0.13186004699999998,-0.213740617,1.183900381,2.056735716,-4.337741606,-4.160464897,-3.174346199,-4.404865196,-4.663567055,-5.285464684,-4.012241135,-3.801842553,-1458.2147465180606 -4805,4805,A276Y,0.022048751000000002,-0.007780253000000001,-0.016696146000000002,-0.004028275,-0.088587526,-0.064410324,-0.01885355,0.06295105200000001,-0.017966233999999998,0.003176037,-0.018736543,-0.034489147000000005,0.001096855,-0.055867707,0.047811157,-0.073288775,-0.103886276,1.494308414,2.495035222,-10.81876335,-11.2983976,-8.696537117,-11.23379858,-10.79633495,-12.06874851,-8.317371861,-7.646493721000001,-1451.8782152128406 -4806,4806,E277A,0.020421894,0.010806663000000001,0.006846636999999999,-0.047800677,-0.084317277,-0.02851198,0.066287795,-0.025444007999999997,0.037917888999999996,-0.025057726000000002,0.046671052000000005,0.016532948999999998,-0.002839675,-0.098409958,0.002808605,-0.103699025,-0.06493552799999999,1.516860251,2.383603024,-1.7020147230000002,-1.373267403,-2.575764549,-2.7128791810000004,-0.798187286,-1.049975197,-1.7272857659999998,-0.850259095,-1457.110458301846 -4807,4807,E277C,-0.023354652000000004,0.015238709,0.011278123000000001,-0.069879971,-0.6154974639999999,0.02866313,0.053307966,-0.10001727,0.07734085,0.007183928000000001,0.02329349,0.0067164780000000006,0.015839768,-0.11366428099999999,-0.026095661000000003,-0.440974436,-0.7900204909999999,1.345469034,1.7749629519999999,-7.9448334460000005,-7.408907982000001,-9.013990585,-9.170588043,-6.423676826,-7.707003792,-7.74544551,-7.230363313,-1462.0901967370883 -4808,4808,E277D,0.041215275,0.0014623779999999999,0.002400105,-0.08024479999999999,-0.061959965,0.034811556,0.097130475,-0.014699926,0.04364712,-0.09314338,0.096068135,-0.044348494,0.049148702999999995,-0.154193197,-0.006296403000000001,-0.124601481,0.0006815510000000001,1.4676791569999998,2.2686011180000003,-0.787553625,-0.810155525,-1.127179634,-0.161002258,-0.7888090440000001,-1.0506216659999998,-1.497576332,-0.478717435,-1464.935137916822 -4809,4809,E277G,0.015894186,0.032356931,0.029230847,-0.005202324,-0.146375894,0.013446301,0.075869963,-0.044081592,-0.0016483429999999998,-0.00836555,0.073079411,0.022096595,0.036365099,-0.049628395,0.039223747999999996,-0.13804624599999998,-0.154705542,1.498467606,2.311117238,-1.4636720019999998,-2.09456488,-1.555823067,-2.385668076,-0.591078323,-0.691225662,-1.303547332,-2.314396311,-1460.8759352276102 -4810,4810,E277F,-0.017330263999999998,-0.015818521000000002,-0.001955407,-0.047509547,-0.9709960059999999,0.023187961,0.04503544,-0.079695967,0.059023708,-0.06838168,0.036744638999999996,-0.047610789,0.043699975,-0.10843792699999999,0.013418834,-0.664691444,-1.277300568,1.3541706430000002,1.640203979,-7.78295049,-7.131377991,-8.803028557000001,-8.818500336,-5.999906975,-8.161938591,-6.088351667,-4.501029945,-1467.871672726702 -4811,4811,E277I,0.02674516,0.052386546,0.082034817,-0.011727811000000001,-0.01757013,0.027342504,0.083245793,-0.029755474,0.028970051,0.070982217,0.033790875,0.11221104900000001,0.051858585,-0.033378472,0.00992285,0.048705822,-0.083846082,1.097952375,2.666035962,-7.15067252,-6.429479706,-8.461775719,-8.250545623999999,-5.630901375,-6.980660179,-5.850008074,-5.066813212,-1466.0192840183154 -4812,4812,E277H,0.016540236,0.028481397999999998,0.027761926,-0.013478223999999999,-0.333711473,-0.014119486,0.058862455999999994,-0.025781983999999997,0.040991694,-0.023497628,0.080460423,0.001921925,0.053601927,-0.069117213,0.042160765,-0.25739284,-0.410030105,1.5186933980000001,2.092570334,-5.512467914,-5.1713074489999995,-6.5163707429999995,-6.496917037999999,-4.2391287460000004,-5.138615593,-4.387670697,-2.9018341860000003,-1460.085040120408 -4813,4813,E277K,-0.0022668379999999998,0.055085321,0.0013251970000000002,-0.039372177,-0.144432723,0.006487571,0.047720422,-0.052254097,0.063334585,0.014966408999999998,0.09520423300000001,-0.030036887,0.032687281,-0.070155306,-0.008589046999999999,-0.11294447199999999,-0.175920973,1.4928048580000002,2.390099507,-2.438361826,-2.092287849,-3.122086487,-3.958044182,-1.105299278,-1.9140913309999998,-2.528163857,-0.907644096,-1459.11206596205 -4814,4814,E277M,-0.002316351,-0.019171449,0.011471608000000001,-0.008560809,-0.253701899,-0.016115138,0.057490763,-0.062123465,0.06617192,-0.022979515,-0.015363382,0.003998208,0.018945008,-0.046405735999999996,0.029284117999999998,-0.216424903,-0.290978894,1.467410869,2.128036376,-6.61972942,-6.0247078929999995,-7.951825562000001,-7.861085602,-5.205350021,-6.055678024,-5.511907997000001,-4.668250237,-1464.4690932761878 -4815,4815,E277L,-0.005365258,0.030166009,0.0342485,-0.0046235,-0.07440751599999999,0.0050975659999999996,0.041512403999999996,-0.05224292,0.029298435,0.023745141,0.036586877000000004,0.034587132,0.033909867999999996,-0.050821065,0.041574066,-0.047742792,-0.10107224,1.318882223,2.493946148,-5.88575791,-5.366078186,-7.516418495,-7.2419723739999995,-3.872319862,-5.4320006329999995,-4.950276888,-3.215516136,-1465.7291936650872 -4816,4816,E277N,-0.057248497999999995,0.030892616,-0.008512259,-0.050059604,-0.077807463,0.017271898,0.015655126999999998,-0.130152123,0.053122975,0.058609412,0.0031758190000000003,0.045469067,-0.062493585,-0.083196358,-0.016922849,-0.022119609,-0.133495317,1.276755325,2.5206573519999997,-3.571744055,-3.095841568,-3.8727821039999997,-4.402131607,-2.805825874,-3.6821391219999997,-4.031186585,-2.30439738,-1461.3147731409408 -4817,4817,E277Q,0.052980545999999996,0.05491105,0.047420889,-0.015463111000000002,-0.046492212000000005,-0.0052483930000000005,0.120838869,-0.014877777,0.038516378999999996,0.017216727,0.09260537199999999,0.031468465,0.063373312,-0.042786448,0.011860226000000001,-0.047231612,-0.045752811,1.2110845,2.347432485,-2.6200011919999997,-1.780935944,-3.854248985,-3.691290825,-1.610403709,-2.163126495,-2.827270372,-0.8676208320000001,-1461.534324273467 -4818,4818,E277P,-0.038016095,-0.01238717,-1.066721951,-2.016079391,-2.622383871,-0.005143305999999999,0.034958381000000004,-0.11099057,0.035336322999999996,-0.014713671999999999,-0.010060666999999999,-0.8431897740000001,-1.290254128,-1.989312446,-2.0428463359999998,-2.389361708,-2.855406033,1.983872644,0.821750433,-7.379614151,-6.668447258,-8.614418144,-8.427169082999999,-6.2050398179999995,-6.982996452,-6.7967149860000005,-6.379811591,-1462.5948994648643 -4819,4819,E277S,-0.0015054629999999999,0.024718659,0.026446672,-0.018985389,-0.123684104,0.011604761000000002,0.047373387999999995,-0.050384314000000006,0.033215354,0.004082055,0.045355263,0.030914627000000004,0.021978717000000002,-0.054125812999999995,0.016155035,-0.100494319,-0.146873888,1.4166213269999999,2.308803801,-2.628682588,-2.102047646,-3.711332954,-3.686816696,-1.187179756,-2.4560358890000002,-3.291112973,-1.4658489469999998,-1459.9440044383518 -4820,4820,E277R,0.015267132,0.019348055,0.026553127000000003,-0.028979583,-0.086642792,0.015111665,0.06622819099999999,-0.035693927,0.012924911,-0.021498694,0.060194803,0.019735393,0.033370861,-0.080208066,0.022248900000000002,-0.10699598800000001,-0.06628959599999999,1.360625206,2.27497444,-2.9439990839999997,-2.73182634,-4.697427536,-3.849660469,-1.6468047559999999,-1.794276321,-2.733408077,-0.743203059,-1457.3944277893752 -4821,4821,E277T,-0.001347203,0.026787441000000002,0.035428137,-0.026144112999999997,-0.10085090199999999,0.029270477000000003,0.050442532000000005,-0.053136937999999995,-0.007021241,-0.03967362,0.093248501,0.010674177,0.060182097000000004,-0.102839091,0.05055086599999999,-0.13447388,-0.06722792400000001,1.3845516969999998,2.18563951,-3.5338443760000002,-3.272731133,-4.000649994,-4.580359436,-2.17082708,-3.644654236,-3.316163995,-1.885857704,-1462.895686472766 -4822,4822,E277W,-0.026001196,-0.007137312,-0.016372995,-0.044038305,-1.5297713590000002,-0.006538233,0.017627132,-0.069629524,0.021208187000000003,-0.050581665,0.036307041,-0.045208881,0.012462892,-0.08564373300000001,-0.002432877,-1.311807809,-1.7477349080000002,0.9757278640000001,1.362554649,-8.852678394,-8.081930473,-10.37750714,-9.884582161,-7.319036278,-8.600335915,-7.47587962,-6.7067509020000005,-1468.9446229287423 -4823,4823,E277V,0.007497515,0.025001303,0.036874386,-0.025952249,-0.169901523,0.019783886,0.074956539,-0.05996151,0.028857715,-0.005515464,0.055518069,0.030579073,0.043169699000000006,-0.082253906,0.030349407999999998,-0.149402741,-0.190400304,1.544053338,2.281105729,-6.199258553,-5.73860424,-7.461063789,-6.930171829,-4.716852974,-6.14959993,-5.638574747000001,-4.352475737,-1465.3724874719046 -4824,4824,E277Y,0.073440804,0.099287529,0.06351747,-0.007164806,-0.677625439,0.030940656,0.152797864,-0.005916256999999999,0.052870798,0.045753694000000004,0.15282136300000002,0.029339566,0.097695374,-0.067293639,0.052964027999999996,-0.515316505,-0.839934373,1.082772004,1.58018952,-8.321023488,-8.02440509,-9.050229919,-9.376322815,-6.453161781,-8.700997832999999,-6.661261153,-5.576851957000001,-1464.3438745569438 -4825,4825,I278A,0.056076494000000005,0.028877332999999998,-0.905099745,-2.035603059,-2.41015192,-0.07566700400000001,0.066785317,0.04536767,0.027280596,0.07314870700000001,-0.015394041,-0.601011448,-1.209188042,-1.980647338,-2.090558779,-2.255627176,-2.564676663,1.3774376730000002,0.673649424,-9.569987471000001,-9.122805,-8.532033669,-12.10747746,-8.440510848999999,-9.647110382000001,-5.048038636,-0.252753314,-1454.3191740210168 -4826,4826,I278C,0.065918774,0.035751885,-0.059023067,-1.5770732969999999,-2.724411475,-0.036649747,0.09932791199999999,0.032509635,0.06572196599999999,0.030089087999999996,0.041414682,0.052336402000000004,-0.170382535,-1.563238011,-1.590908582,-2.450037677,-2.998785273,0.585040879,0.693055455,-11.93246632,-10.99329163,-13.01908903,-14.849301,-11.38590974,-9.414740189,-7.404019872999999,-4.375159422,-1460.0566771095619 -4827,4827,I278E,0.062813934,-1.417552949,-1.7368482669999998,-2.11235497,-2.768557532,0.002203827,0.08518151,0.040446357,0.096017496,-1.311130323,-1.523975575,-1.767665047,-1.706031487,-1.919180678,-2.305529262,-2.629889085,-2.9072259789999997,3.822299005,1.6798396009999998,-14.74915459,-14.383946700000001,-15.16718099,-16.8797562,-13.77609933,-13.53878972,-9.977288552000001,-9.693275619,-1449.0550530478358 -4828,4828,I278D,0.032391768,-1.8450947530000001,-2.244240492,-2.150821148,-2.7189780810000004,-0.003324025,0.072799848,-0.008016312,0.0183429,-2.177111928,-1.5130775769999998,-2.156525397,-2.331955587,-2.3080410280000003,-1.9936012680000001,-2.541628181,-2.896327981,-0.704536803,-1.130024621,-15.01972886,-14.64855177,-15.67748311,-17.58568492,-13.66431274,-13.52261175,-9.977288552000001,-9.693275593,-1450.0957438596524 -4829,4829,I278G,0.045045383,-1.397642504,-1.981529313,-2.1683006209999998,-3.270264765,-0.025708788,0.079393975,0.010696791,0.065685841,-1.3720305640000001,-1.423254443,-1.870688493,-2.0923701319999997,-2.087144931,-2.24945631,-3.511063783,-3.029465746,-0.8733494340000001,-1.111130082,-14.94687464,-14.55639507,-15.22080136,-17.83537323,-13.61082409,-13.51097946,-8.996816221,-6.773250018,-1458.3028277722187 -4830,4830,I278F,0.075004417,-0.028025586,0.06614773,-1.197257717,-2.779089453,-0.08695760400000001,0.107313311,0.042695523,-0.107637106,-0.06781084799999999,0.011759677,0.022225618,0.11006984199999999,-0.585527703,-1.808987731,-2.670373204,-2.887805702,0.813131357,0.847523415,-10.23249992,-9.626586319,-10.85892978,-11.46787797,-9.776989151,-9.432116402,-6.963039209,-4.431209841,-1457.3729307097383 -4831,4831,I278H,0.022980293,-1.1288702259999999,-1.750135979,-2.2481819769999998,-2.801357298,-0.024986418,0.067765057,-0.021804472000000002,0.069690439,-1.1274859259999999,-1.130254525,-1.58402065,-1.916251308,-1.7935282280000002,-2.7028357260000004,-2.395092166,-3.20762243,3.836518748,1.907514691,-15.10958502,-13.90549351,-16.17165051,-17.87835545,-13.72857601,-13.86384961,-9.977288552000001,-9.693275573,-1452.509913478978 -4832,4832,I278K,0.028567112000000002,-1.668862871,-1.806569238,-2.324074269,-2.392231202,0.028536968,0.065829579,-0.008695356,0.002722858,-1.411025189,-1.9267005519999998,-1.867559913,-1.745578562,-2.019075544,-2.6290729930000003,-2.252662697,-2.531799706,-0.30948849300000003,-0.856612659,-14.0848083,-13.59405472,-14.71755333,-16.05938984,-12.58090678,-13.47213683,-9.977288552000001,-9.693275584,-1444.0189534206875 -4833,4833,I278M,0.069461297,0.049382435999999995,0.027597952000000002,0.035536512,-0.522765186,-0.06749736099999999,0.1080133,0.030909292999999997,-0.095063632,0.069080919,0.029683952000000003,0.003186965,0.052008938,0.010238248,0.06083477599999999,-0.326693028,-0.7188373440000001,1.040272799,1.684636361,-6.402777736,-6.337168297000001,-7.415621361,-7.194451614,-5.821820992,-5.244826416,-5.7505353779999995,-3.092388428,-1461.1755676767789 -4834,4834,I278L,0.02015708,-0.006131221,0.042032731,0.042220060999999996,-0.61840592,-0.023898532000000004,0.035174343999999996,0.005139815,0.028627474,0.028711251,-0.040973692,0.066075192,0.017990269,0.045062612,0.03937751,-0.40022498,-0.8365868590000001,0.848657977,1.542419891,-3.757869556,-3.94019812,-4.591186295,-4.456968964,-2.92995623,-2.87103817,-2.9045365839999997,-1.260680654,-1459.8595995935611 -4835,4835,I278N,-0.0036913959999999996,-1.383026415,-1.481142159,-2.450192183,-2.518349116,-0.09559506699999999,0.002771456,-0.010154248000000001,0.055595360999999996,-1.5019448380000002,-1.264107992,-1.356419571,-1.6058647469999998,-2.109995193,-2.7903891730000003,-2.343582346,-2.693115886,3.337052772,1.280878699,-14.32874286,-13.52383824,-15.44965825,-16.9105555,-13.268068300000001,-12.491594000000001,-9.977288552000001,-9.693275553,-1454.8027469390072 -4836,4836,I278Q,0.03504747,-0.938294285,-2.106349572,-2.198735763,-2.8821171569999997,-0.080533878,0.052638227999999995,0.017456711,0.12437637900000001,-0.640734687,-1.2358538829999999,-2.352541916,-1.860157228,-2.504057547,-1.893413979,-2.7376447,-3.026589613,0.334101503,-0.536750225,-14.0307673,-13.78402149,-14.70478193,-16.45904272,-12.11251338,-13.09347699,-9.977288552000001,-9.693275571000001,-1453.0184351052158 -4837,4837,I278P,0.033718616,-1.418717578,-1.9494840340000001,-2.3540861140000002,-2.732630383,-0.02038558,0.060098527,0.007338705,0.038612642,-1.350296036,-1.487139119,-2.0286795090000003,-1.870288559,-2.282857482,-2.4253147459999997,-2.6511432090000002,-2.8141175560000002,0.128680822,-0.821789707,-14.86634902,-14.35851046,-15.09696471,-17.30838338,-13.78354916,-13.78433737,-9.977288552000001,-9.693275599,-1466.6041752700694 -4838,4838,I278S,0.052937463,-0.88193843,-1.978042302,-1.8196572290000002,-2.9043248839999998,-0.045775202,0.084024376,0.021850549,0.067296853,-0.514962814,-1.248914045,-2.177423321,-1.7786612819999998,-1.9139656040000002,-1.7253488540000002,-2.562526105,-3.246123663,0.628439515,-0.438363358,-11.86347583,-10.903396800000001,-12.76568087,-14.49189594,-10.86150108,-10.29490448,-6.5798735079999995,-3.81254783,-1457.2751083779149 -4839,4839,I278R,0.060562940999999995,-1.534849795,-1.8645005430000001,-2.115274629,-2.68954879,-0.033131503,0.08398932099999999,0.037136561,0.024460082999999997,-1.497266576,-1.5724330130000002,-1.693389155,-2.035611931,-1.9961724619999999,-2.234376796,-2.609970856,-2.769126724,3.648520262,1.3990449969999998,-14.57268063,-14.40202109,-15.02070216,-16.8340152,-12.96193227,-13.64473245,-9.977288552000001,-9.693275551000001,-1440.0971803963184 -4840,4840,I278T,-0.026246092000000002,0.000783217,-0.39724831299999996,-1.66426204,-2.2320846430000003,-0.052512998,0.024446786,-0.07693897,0.062830223,0.078464543,-0.07689811,-0.066842835,-0.7276537909999999,-1.6766528630000002,-1.651871216,-2.252662697,-2.211506588,0.823540921,0.6979712309999999,-7.864695319,-7.1918115689999995,-7.531070327999999,-8.079557076,-8.162893578,-8.358144043,-4.445008803,-1.800922685,-1461.0071380631998 -4841,4841,I278W,0.028259215,-0.058341937,-1.059824487,-1.756913837,-2.9586566339999996,0.004918201,0.08644029800000001,-0.029921867999999997,0.017499161000000003,-0.028113709,-0.088570164,-0.774270413,-1.34537856,-1.8800285540000001,-1.63379912,-2.812585711,-3.104727557,2.0155219140000002,0.882050157,-13.88598817,-13.4723839,-14.63556781,-15.63789467,-13.05714108,-12.6269534,-9.977288552000001,-9.693275597000001,-1457.1693151076324 -4842,4842,I278V,0.051657167999999996,0.033056886,0.05060728900000001,0.014369836,-0.232038281,-0.01799932,0.061227442,0.042086893,0.08628676699999999,0.05857877400000001,0.007534997,0.053344214,0.047870364000000006,0.044035662999999996,-0.015295991,-0.174275784,-0.289800778,1.253981014,2.066721783,-3.526197812,-3.294229965,-2.49047261,-4.6774621960000005,-3.2580514369999998,-3.91077285,-4.5571100410000005,-0.20912949600000003,-1461.3088925550692 -4843,4843,I278Y,0.049432917,-0.672297378,-1.949380546,-2.5064762000000003,-2.5746331330000003,0.042156168,0.131059685,-0.032193852,0.063598026,-0.325853579,-1.018741177,-1.58402065,-2.3147404419999997,-2.036566276,-2.976386123,-2.270153429,-2.8791128360000005,3.799390638,2.094074671,-13.12294019,-12.39918124,-14.34595773,-14.60875337,-12.29360677,-11.96720184,-8.970978559,-6.618413068,-1457.7700447309762 -4844,4844,G279A,0.035083303999999996,-0.032186025,-0.013159029,-0.0032020190000000004,-0.144679187,-0.069718238,0.037740699999999995,0.032425907000000004,-0.001010239,-0.037498792999999996,-0.026873256,-0.018709422,-0.007608635999999999,0.003637809,-0.010041847,-0.149199212,-0.140159162,1.452302797,2.2741593769999997,-4.3991343480000005,-4.91506012,-4.970529839,-4.7851548919999995,-3.18550975,-4.139417137,-4.7831819289999995,0.564551247,-1453.5364553844556 -4845,4845,G279C,0.03151748,-0.026482436,0.013056864,0.033366771,-1.062366435,-0.126928682,0.046972720999999995,0.016062239,-0.032333613,-0.007090698,-0.045874174000000004,-0.03903644,0.065150167,0.076900598,-0.010167055999999999,-0.9779716999999999,-1.14676117,0.610259045,1.348010358,-11.84284135,-12.67624622,-12.39539081,-13.47169671,-10.15562521,-10.515247800000001,-9.15576674,-5.980533335,-1449.9826802853495 -4846,4846,G279E,0.005416384000000001,0.012067668,-0.878178737,-1.935768219,-2.340217753,-0.115251514,0.013305576999999999,-0.002472809,0.058230635999999995,-0.09380864,0.117943975,-0.47645947299999997,-1.2798980009999998,-1.736215541,-2.1353208969999997,-2.058966791,-2.621468714,3.25636845,2.088183917,-12.38293445,-12.69776743,-12.45172106,-14.22418253,-11.17755183,-11.36344942,-10.58585342,-9.379787925,-1461.4620384532027 -4847,4847,G279D,-0.029044134,-0.8545739440000001,-2.063879468,-2.4362256230000003,-2.457716759,-0.012036937,0.049457115,-0.10754538300000001,-0.000569711,-0.47751612,-1.231631767,-1.969730828,-2.158028107,-1.8831339219999998,-2.9893173230000003,-2.586096414,-2.329337104,3.447923629,1.555061337,-11.772696400000001,-11.92055965,-12.26712797,-13.44915276,-10.60490658,-10.62173504,-9.673791891,-6.710562507000001,-1462.802936162334 -4848,4848,G279F,0.045047277999999996,0.015083473,0.051430795999999994,-0.7164667370000001,-2.0084977569999998,-0.18796916,0.035834656,0.05425990000000001,-0.047112545,-0.031159642999999997,0.061326588,-0.00450867,0.107370262,-0.481933241,-0.9510002320000001,-1.827250319,-2.189745194,1.675264696,1.419853703,-13.09671808,-14.17227074,-13.78717834,-14.08385156,-11.71718905,-11.72310072,-9.610975058,-6.535952267000001,-1436.0300151719712 -4849,4849,G279I,-0.010072221999999999,-0.099754063,-0.051053203,-0.646870635,-1.940218459,-0.131474791,0.018001295,-0.038145738,0.050343407,-0.022823671,-0.176684455,0.010181583000000001,-0.112287988,-0.236220713,-1.0575205570000001,-1.6503876659999999,-2.230049251,1.379284386,1.383938149,-13.88539047,-15.59617775,-13.68665834,-16.44673135,-11.69564648,-12.00173843,-9.079843102,-6.318015759,-1433.2544624446891 -4850,4850,G279H,0.015607238999999998,-0.025921147000000002,-0.559668554,-1.859004136,-2.631557034,-0.076138964,0.028232437000000003,0.00298204,-0.041414129,-0.056268092,0.004425799,-0.301029996,-0.818307111,-1.76075137,-1.957256902,-2.7269552960000003,-2.536158772,1.4244761830000001,0.7574418009999999,-13.10324638,-13.57627797,-13.78960477,-14.06519797,-11.88680075,-12.19835043,-10.59389423,-9.402820286,-1455.4773129294626 -4851,4851,G279K,-0.016716695,-0.620964551,-2.128942205,-2.390363985,-2.47432449,-0.08934065599999999,0.100956735,-0.134390125,-0.032263424,-0.427168592,-0.8147605090000001,-2.037482612,-2.220401797,-2.126976965,-2.653751005,-2.352818202,-2.5958307769999998,1.2099324759999999,-0.13442447,-13.06173776,-13.51913237,-13.06761275,-15.00838102,-11.62739579,-12.08616689,-10.59389423,-9.402820286,-1464.0428275763988 -4852,4852,G279M,-0.04877950599999999,-0.00516402,-0.006060875,-0.29554102,-1.7132280009999998,-0.132425574,-0.004543443,-0.093015568,-0.013589511,0.023011035,-0.033339075,0.049626002,-0.061747752,-0.020124293,-0.570957746,-1.422056789,-2.004399212,0.45351015100000003,1.312111566,-11.3868215,-12.84522128,-9.721073952000001,-14.39895261,-9.435954062999999,-10.53290557,-7.464215918,-4.4819620030000005,-1441.4186111493036 -4853,4853,G279L,0.023121024,-0.034256785,0.01195786,-0.590287792,-1.7301822119999999,-0.16306207,-0.012345206999999999,0.058587254000000005,-0.030122668999999998,-0.049674864000000006,-0.018838705,-0.027921127999999996,0.051836848,-0.361655503,-0.8189200809999999,-1.668981941,-1.791382482,1.56996557,1.4314362330000001,-14.18848948,-15.27959137,-13.71591731,-17.07220944,-12.41383508,-12.4608942,-10.52752701,-8.935342308,-1431.0175685901195 -4854,4854,G279N,-0.0688805,0.007207674,-0.09067189199999999,-1.404416954,-2.428784255,-0.000829236,0.057179403,-0.194940403,-0.075757726,-0.072694277,0.08710962400000001,-0.112342484,-0.069001299,-1.303068224,-1.505765684,-2.130969453,-2.726599057,2.40748187,1.541304139,-11.74133575,-12.73100261,-11.60441441,-13.454812699999998,-10.8548148,-10.06163426,-9.611257592000001,-6.712529404,-1460.8291723765433 -4855,4855,G279Q,-0.000674041,0.008410374,-0.329597648,-1.821198371,-2.624825223,-0.074202246,0.022672906,-0.024020987999999997,-0.064353979,-0.04616423,0.062984978,-0.225622729,-0.433572567,-1.536175487,-2.106221255,-2.502379414,-2.7472710310000004,1.339068178,0.774209275,-12.27831988,-12.74825313,-12.2106631,-14.43006277,-10.91652138,-11.08609903,-10.02683485,-7.364347617000001,-1459.3711158479564 -4856,4856,G279P,0.015901238999999998,-0.83331947,-1.94945741,-2.078344168,-2.7982254760000003,-0.063610445,0.011869478000000001,0.019933000000000003,0.026474935,-0.637747713,-1.028891226,-2.052586975,-1.8463278440000002,-2.054931153,-2.101757182,-2.79928633,-2.7971646210000003,1.4430964569999998,-0.13670242400000002,-12.68594377,-13.174462300000002,-12.68875695,-14.235978,-11.41814249,-11.91237912,-9.618949954,-6.709987607,-1465.2056767870672 -4857,4857,G279S,0.003946601,-0.025150499,-0.016562023000000002,0.016438826,-0.343477982,-0.066889618,-0.010367531999999999,0.018260733,-0.020194877,-0.041025057999999996,-0.00927594,-0.040134222000000004,0.007010176999999999,0.021495393999999998,0.011382258000000001,-0.28901181800000003,-0.397944145,1.213425211,1.836332496,-5.6218242720000005,-6.443435622999999,-6.837715508,-6.886850807,-4.425131218,-3.515988205,-5.562993167,-0.104864469,-1462.6002164632082 -4858,4858,G279R,-0.033398582999999996,-0.5654163320000001,-1.889226946,-1.9987098069999998,-2.726890745,-0.028573312000000003,-0.018602143,-0.048195023,-0.007219631,-0.285756944,-0.84507572,-1.93142922,-1.847024671,-1.844832314,-2.152587299,-2.496642283,-2.957139207,1.095507857,-0.06830159,-12.08705377,-12.552339300000002,-12.35028331,-14.34890885,-10.25864632,-10.92509108,-9.373243636,-6.318015742,-1460.0848875846714 -4859,4859,G279T,0.014495283000000001,-0.024648527000000003,-0.012319446999999999,0.019491731,-1.678160555,-0.111023804,-0.008623725,0.03761429,-0.013559612,-0.022746456,-0.026550597999999998,-0.025158877000000003,0.000519983,0.06579033599999999,-0.026806875,-1.6639653319999999,-1.692355777,0.5711923329999999,1.30799748,-8.105794716,-9.183267929,-7.00078318,-11.76880763,-6.2183761220000004,-6.357738716,-6.148769525,-0.726459904,-1454.966280556284 -4860,4860,G279W,0.029707326000000003,-0.024021487999999997,-0.08026768299999999,-1.537666186,-2.295020434,-0.18865384300000002,0.034229827000000004,0.025184823999999998,0.006363301,-0.021740562,-0.026302412999999997,0.003738381,-0.164273747,-1.3303423090000002,-1.7449900630000001,-2.459273533,-2.130767334,0.70397686,0.718568823,-13.79455441,-14.27525241,-14.38844505,-15.64309074,-12.16962045,-12.49636343,-10.59389423,-9.402820286,-1442.442484323401 -4861,4861,G279V,0.020557686000000002,-0.004060423,-0.003508372,-0.456489365,-1.91550309,-0.187586318,0.029302545,0.011812826,-0.057438011,-0.021187125,0.01306628,-0.035848659,0.028831916000000003,-0.218384964,-0.694593765,-1.8486322519999998,-1.9823739269999998,1.239326325,1.340229511,-10.80466221,-11.71678468,-11.21245773,-13.6775176,-8.154507042,-9.262043968,-6.701905238999999,-2.8401942160000004,-1439.7271964624524 -4862,4862,G279Y,-0.025694175,-0.007533051999999999,-0.041436918999999996,-1.39304885,-2.126980805,-0.249950124,-0.09422345300000001,0.042835104000000006,-0.012657035,-0.0056921459999999995,-0.009373958,-0.066395546,-0.016478291000000003,-1.5756096819999998,-1.210488017,-1.947578955,-2.306382654,3.137502062,2.144082874,-13.62306969,-14.00416248,-14.84832811,-14.59426494,-12.34747366,-12.32111926,-10.33023528,-7.961943686000001,-1441.245537261013 -4863,4863,A280C,-0.012123014,0.005180578,0.006360944,0.026847236,-0.42295384399999997,-0.04859699,-0.050141592,0.025895565,0.04235680000000001,0.016852827,-0.0064916719999999995,0.024187019,-0.011465132,0.038886317999999996,0.014808153000000001,-0.243557561,-0.602350126,1.132350998,1.834234278,-7.138248729,-6.5515447689999995,-7.66185553,-7.636461402999999,-7.396858025,-6.444523918,-8.578425567,-8.166355106000001,-1462.675002721604 -4864,4864,A280E,-0.068131829,-0.010652531000000002,-0.044225234,-0.023658127999999997,0.017609574,-0.004638617,-0.077869781,-0.058393877000000004,0.002337956,0.040451276,-0.061756338,-0.01731095,-0.071139517,0.019574082,-0.066890338,0.07909559,-0.043876443,1.075653676,2.805858865,-1.431726546,-0.897412155,-2.161764984,-1.325609276,-1.861209862,-0.912636452,-2.558286352,-0.310539899,-1466.3267319831066 -4865,4865,A280D,-0.060825261,0.079135888,0.012624161000000002,0.02748281,0.0026237979999999997,0.012943793,-0.02575471,-0.095895812,0.045115712999999995,0.11376284,0.044508935,0.079243719,-0.053995398,0.127950798,-0.072985178,0.031826022999999995,-0.026578427,1.054305364,2.766293118,-2.959758578,-3.1637553560000002,-2.8032171630000002,-3.156321953,-2.9573259430000003,-2.718172478,-3.69589031,-2.748780747,-1467.8666400415823 -4866,4866,A280G,-0.028084208,0.032488889,-0.009374351,-0.004871993,-0.030074452999999998,-0.02445038,-0.06793450599999999,0.011766091000000001,0.006655706999999999,0.057650043,0.007327735,-0.004435183,-0.014313518999999999,-0.001137383,-0.008606602,-0.014858978,-0.045289927,1.361151851,2.6363844690000002,-2.699690225,-2.382833427,-3.141731659,-2.0860739440000002,-3.382511063,-2.5053010330000003,-4.430067201,-1.824280479,-1465.0803253250197 -4867,4867,A280F,-0.0033699109999999997,0.09971469300000001,0.000668165,0.042391037,-0.02941169,0.016562666,-0.084948933,0.078209112,0.062382738,0.105636219,0.093793166,0.013668392,-0.012332063,0.039626173,0.045155900000000006,-0.021671094,-0.037152285,1.284620528,2.631746913,-7.264147266,-6.339791618,-7.788956841,-8.125723488,-7.9400709460000005,-6.126193436,-6.772227335,-3.779980548,-1464.5135107482783 -4868,4868,A280I,-0.090391735,0.034865863,-0.080872316,0.006725180999999999,-0.036654566,0.037384397,-0.102210428,-0.078573041,0.165819234,0.066449324,0.0032824020000000002,-0.052252757000000004,-0.109491874,0.048984495999999995,-0.035534135,-0.013861428,-0.059447704000000004,1.222799075,2.6091865569999997,-6.331086253,-5.841335213,-7.811389709,-5.750956497000001,-7.054577637,-5.197172211,-6.381855316,-4.438068099,-1468.1553399809636 -4869,4869,A280H,-0.012493345,0.038923493999999996,-0.032212807999999996,0.015057306000000001,-0.00561883,-0.078405741,-0.052569378,0.027582687999999998,0.011639449,0.07594698799999999,0.0019,-0.00655758,-0.057868036,0.065331573,-0.035216961,0.048224166,-0.059461825,1.211130532,2.9389808389999996,-3.784533521,-3.2129159389999997,-4.17752282,-4.200681366,-4.24639418,-3.0851532969999997,-4.418092198,-2.1934723309999997,-1466.403486596886 -4870,4870,A280K,-0.020814739,0.04003729,0.070316406,0.017820957,0.075160398,0.118836564,-0.017571261,-0.024058216,0.194957088,0.043708359,0.036366221000000004,0.137425235,0.003207577,0.072859906,-0.037217992000000005,0.05945985,0.090860946,1.238730648,3.03239212,-1.184081187,-0.611637024,-1.896820274,-2.051867912,-1.036351318,-0.323729408,-1.871969105,0.689393378,-1470.375108299777 -4871,4871,A280M,-0.009311223,0.039352789,-0.020111633,0.053095138,0.037007801,-0.001755541,-0.055072618,0.036450172,0.160396349,0.040981227,0.03772435,0.012478395,-0.052701661,0.064932038,0.041258237999999996,0.10091253300000001,-0.026896931000000002,1.136552211,2.9797088310000004,-6.49145141,-5.281763527,-7.348269585,-6.782271965,-7.379421592999999,-5.66553038,-6.564189695,-4.463718895,-1465.9244924853556 -4872,4872,A280L,-0.019694195,0.025673355,-0.01540002,0.007323596999999999,-0.032356586,-0.057590987,-0.072462931,0.033074541,-0.041337933,0.039685653,0.011661056000000001,0.004835358,-0.035635398,0.002207067,0.012440126000000001,0.006857073000000001,-0.071570244,1.211678106,2.6355949969999997,-4.813150089,-4.032753578,-5.564761322000001,-4.840736778,-5.8643560489999995,-3.763142715,-5.606936851,-1.7401011290000001,-1468.0014289100654 -4873,4873,A280N,-0.100248609,-0.018032502,-0.058417893,-0.017596726,0.011650471,0.051055959000000005,-0.14568825800000001,-0.054808959000000004,0.173896735,0.033277352999999996,-0.06934235700000001,-0.008394361999999999,-0.10844142300000001,0.001750831,-0.036944283,0.03792009,-0.014619149,1.010840145,2.6171390469999998,-3.237784247,-3.241913925,-3.439167419,-3.8596982189999998,-3.2476220469999997,-2.400519623,-4.048414061,-2.579443896,-1466.8518672832288 -4874,4874,A280Q,0.027686207,0.025232728,-0.048104238,-0.025300793999999998,0.001830592,-0.096644102,-0.016242965,0.071615379,0.015339323,-0.022432942999999997,0.072898398,-0.102096837,0.005888361999999999,-0.037828254,-0.012773333999999999,-0.01482549,0.018486673999999998,1.253057574,2.527943263,-2.338502061,-1.304825294,-2.531812386,-2.752311676,-3.691079041,-1.412481911,-4.0949761360000005,-1.0728794659999998,-1470.8015304091386 -4875,4875,A280P,-0.052883669,-0.25733373,-1.6387152740000002,-2.026569518,-2.494082504,-0.00500672,-0.053874835,-0.051892502,-0.01778646,-0.024267108,-0.49040035200000004,-1.546081799,-1.7313487490000001,-2.017006479,-2.0361325569999997,-2.489746225,-2.498418782,0.68246934,0.032625318,-6.340728437999999,-5.618385521,-6.792258232000001,-6.4689069439999995,-6.906109055,-5.917982437,-7.183336431,-5.852633053,-1469.2631213148125 -4876,4876,A280S,-0.10375860699999999,0.036970363,-0.000966615,0.011164307,-0.015325554,-0.019862738,-0.154398868,-0.053118346,0.024947887999999998,0.058761016,0.015179709,0.022746318999999997,-0.024679548,0.035314076,-0.012985462,0.045050127,-0.075701234,1.067914636,2.733284345,-1.4658669919999998,-1.090643898,-1.631773102,-2.087677582,-1.56996637,-0.94927401,-3.188115681,-0.958801899,-1463.913340758998 -4877,4877,A280R,0.017740767,0.05951084,0.0066375769999999995,0.031565471,0.030679468999999997,-0.035991029,-0.010064205,0.045545737999999995,0.007392147,0.067349827,0.051671853,0.033894026,-0.020618873,0.032269788,0.030861154,0.058416162,0.002942776,1.095273149,2.7862396339999997,-1.0638034729999999,-0.16541465,-2.024160873,-0.934769829,-1.862074379,-0.332597633,-2.244745634,1.42050813,-1466.898980928585 -4878,4878,A280T,-0.048665015,0.063407862,0.026680456,0.006376666,-0.043402807,-0.05856134599999999,-0.08800637900000001,-0.009323651,0.019177593,0.10099025699999999,0.025825466000000002,0.077937537,-0.024576625,0.036448562000000004,-0.02369523,0.006806875,-0.09361248900000001,1.187963924,2.7009606410000004,-2.185598773,-1.739236038,-3.2333924260000004,-2.007458435,-1.444947906,-2.502959061,-4.939772733,-1.59533492,-1464.315556857735 -4879,4879,A280W,-0.038685722,0.078896382,0.036756765,0.038898168999999996,-0.06352932900000001,-0.025649927000000003,-0.098913037,0.021541592999999998,-0.005865896,0.114410144,0.04338262,0.057997495,0.015516034,0.088844195,-0.011047857,-0.015685587,-0.11137307099999999,1.320991183,2.6880333519999997,-7.252454016000001,-6.233908027999999,-7.758049736,-7.44266568,-8.285116524,-6.542530113,-6.966581261,-4.720765437,-1462.6683944310062 -4880,4880,A280V,-0.057265897999999996,0.043899445999999995,-0.0007795289999999999,0.018186573,0.001853805,-0.037710621,-0.055955917,-0.058575878,0.015356202,0.063123972,0.02467492,0.029402109,-0.030961166000000002,0.029258505,0.007114641,0.01941985,-0.015712241000000002,1.1928235059999999,2.7976534269999997,-4.861397794,-4.380884155,-5.938834618,-4.366484299,-5.466163773,-4.154622123999999,-5.364610357,-3.554281568,-1469.2935103867203 -4881,4881,A280Y,-0.009454823000000001,-0.029276731,0.007612951999999999,0.005662316999999999,-0.060442832,-0.027633511,-0.07552735299999999,0.056617707,0.084827758,-0.030583528,-0.027969934,-0.021769447999999997,0.036995351,0.0066698669999999995,0.004654767,-0.035173565,-0.085712099,1.2318136990000002,2.464042643,-6.434412991,-5.711936287,-6.985424469,-7.251418655,-6.69424234,-5.529043205,-6.376621215,-3.2260692389999996,-1465.2600975874811 -4882,4882,S281A,0.01085553,-0.015615371999999999,0.007514437,-0.039074234,0.016871306000000003,0.010089789,-0.002499243,0.024210303,-0.016133236000000002,0.0028123609999999998,-0.034043104,0.023667262999999997,-0.00863839,-0.019060533,-0.059087935,-0.021681544,0.055424155999999995,1.217323422,2.511087281,0.14427984,-0.276025124,0.283797142,0.457348663,-0.21779145100000002,0.474069969,-1.6031158859999999,2.38968392,-1459.6078779669479 -4883,4883,S281C,0.053243195,-0.048376630999999996,0.025057258,-0.001752361,-0.23962318300000002,0.10622102900000001,0.069766883,0.036719507,-0.001240994,0.036123201,-0.132876462,0.096226065,-0.04611155,0.078779399,-0.082284121,-0.09481436800000001,-0.384431997,1.297311562,2.346617768,-5.707864627,-6.809401367,-6.401614891,-4.579835785,-5.777933029,-4.970538063,-5.787106692999999,-2.106891927,-1463.3133846097626 -4884,4884,S281E,-0.007462842,-0.033342317,-0.043318389000000006,-0.023829752000000003,0.019996552,-0.040562389,-0.017109755,0.002184072,0.034342079,0.009265406,-0.075950039,-0.002017359,-0.084619418,-0.039557422,-0.008102082,0.004274437,0.035718666,1.297628574,2.6812648269999997,-2.8093740510000003,-3.967486343,-2.861523804,-2.701222801,-3.0455704189999997,-1.4710668869999999,-3.321301437,0.440367555,-1467.0014057168737 -4885,4885,S281D,-0.077237476,0.0029675929999999997,0.040606798,-0.042394062,-0.313969132,0.002262854,-0.113210404,-0.041264547,0.014181001,0.031783352,-0.025848166000000002,0.112432165,-0.031218568999999998,0.07422113,-0.15900925400000002,-0.16092539,-0.46701287399999997,1.2851074359999999,2.1269862969999997,-6.070603934,-7.370316093,-6.429463516,-4.561423157,-5.710173973,-6.281642928999999,-5.305890456,-1.6161453609999998,-1469.7765675019473 -4886,4886,S281G,0.005881285,-0.002000622,0.019861891,-0.010184149,-0.975169465,-0.020873779,-0.003243367,0.015005936999999999,0.012599661000000002,-0.0075252819999999995,0.003524039,0.006250759,0.033473022000000005,-0.008162828,-0.012205468999999998,-0.627710791,-1.322628139,0.903425576,1.460877675,-5.111068877,-5.824794464,-4.640191231,-4.148793312,-5.159087387,-5.782477988999999,-5.097862031,-1.862763575,-1465.0358061022125 -4887,4887,S281F,0.005835314,-0.030240181,0.03461422,-0.02603058,-0.310771785,-0.016534306000000002,0.042427538,-0.03075691,-0.11782147300000001,-0.063410001,0.00292964,0.056097074000000004,0.013131366,-0.08209221400000001,0.030031053999999998,-0.228832856,-0.39271071399999996,1.40879113,2.0563085009999997,-6.816553835,-9.1019636,-7.646335411,-4.393347389,-6.8275521470000005,-6.113570625,-4.957149329,-1.6703134080000002,-1466.6823462517932 -4888,4888,S281I,0.016365684,-0.036928014,0.08486692800000001,0.013927195,0.005375411,0.039656366,0.04474883,-0.012017463,-0.13261905699999998,-0.03697463,-0.036881397999999996,0.087358428,0.082375427,0.030403221,-0.002548832,0.032532574,-0.021781752,1.104549657,2.74042157,-3.6129030589999998,-5.633551964,-3.5986490630000003,-1.71165712,-3.376043503,-3.744613647,-3.20696145,1.8718924890000002,-1470.8427388067357 -4889,4889,S281H,0.054028882,-0.018238115,-0.004022538,-0.025059518,-0.0019367639999999999,-0.03088645,0.103399745,0.004658019,-0.017932383,0.005001527,-0.041477756,-0.015201859,0.007156783000000001,-0.024961696000000002,-0.025157339,-0.02463699,0.020763462,1.117285712,2.33927119,-5.241298933,-7.120121147000001,-6.220229385,-3.795232613,-5.0710452880000005,-3.9998662339999997,-4.513869297,-0.754445797,-1464.9652847619727 -4890,4890,S281K,0.102200117,0.082772843,0.056158442999999995,0.010449293,0.039123014,0.05533324,0.130421793,0.07397844099999999,0.007471789,0.056828697000000004,0.108716988,-0.031791173,0.144108058,0.08435519,-0.063456605,0.07299372400000001,0.005252303000000001,1.073481308,2.84020224,-5.215079967,-6.733151085,-5.168685638,-4.383788292,-4.709787872,-5.079986946,-4.965727952,-0.8076212759999999,-1459.056885364931 -4891,4891,S281M,0.046340324,0.002224116,0.047706904,-0.0048645929999999995,-0.060161433,-0.128979141,-0.024259905,0.11694055199999999,-0.10454083900000001,-0.093797547,0.098245779,0.015665204,0.079748604,0.03809005,-0.047819235999999994,-0.04566276,-0.07466010599999999,1.334238511,2.487937686,-4.2298728,-4.375156494,-3.083568878,-2.550840004,-4.812668228,-6.327130394,-4.290896452,0.515005333,-1470.0611439808272 -4892,4892,S281L,0.065905107,-0.011631881,0.0018307310000000002,-0.018031974,-0.086506977,-0.091464956,0.062313445999999995,0.069496768,0.004320266,-0.010883368999999999,-0.012380391999999999,-0.067961653,0.071623115,-0.053169311,0.017105363999999998,-0.13584259099999998,-0.037171362,1.442559124,2.277564226,-3.177297583,-4.062046188,-3.341900551,-1.9652663119999998,-3.205964935,-3.3113099289999997,-2.280737296,2.077289625,-1470.1210652110167 -4893,4893,S281N,0.040756012,-0.002860834,0.122798357,0.08466909800000001,0.131987915,-0.107879686,0.068735407,0.012776616000000001,0.030787635,-0.03542713,0.029705462999999998,0.20039794100000002,0.045198772000000005,0.127648467,0.041689727999999995,0.132208125,0.131767704,1.671448915,3.643209181,-6.011227292999999,-7.464455002,-6.939250213999999,-4.728059029,-5.824749344,-5.099622879,-6.295904547999999,-2.379626388,-1466.1013647103682 -4894,4894,S281Q,0.055194085,0.005230144,0.042824474,0.036296139,0.020266376000000003,0.06591668099999999,0.059088891,0.051299279,-0.015463793,0.010167368000000001,0.000292919,0.081910575,0.0037383720000000002,0.028228482000000003,0.044363795,-0.018068113,0.058600865,1.2324898229999999,2.596282822,-4.1971632869999995,-5.045309669,-5.003689911,-3.342460945,-4.060533295,-3.5338226169999998,-3.516328582,-0.41965192799999995,-1467.1079559223726 -4895,4895,S281P,-0.027270932999999997,-0.031339725,0.0074379630000000006,-1.335726389,-2.321086677,-0.026976293999999998,-0.016570323,-0.037971542000000004,-0.016017306000000002,-0.015280152,-0.047399297,-4.95e-05,0.014925426,-0.775924246,-1.8955285309999998,-2.148886691,-2.493286663,1.76810787,1.345903506,-7.948367554,-8.867920776,-8.178661491,-6.755058891,-8.11775206,-7.82244455,-8.34258018,-6.633886492,-1466.2175333588384 -4896,4896,S281R,0.005082779,-0.012305844,0.021350131,-0.020843979,-0.042061968,-0.02472358,-0.007199574,0.017365132,0.000983058,-0.015506032,-0.009105655,0.010623276999999999,0.032076983999999996,-0.022133862999999997,-0.019554095,-0.055785454000000005,-0.028338481000000002,1.271390899,2.402791355,-4.476138364,-5.889950377999999,-5.344072716,-3.27811203,-3.923041885,-3.9455148089999996,-3.07421391,0.0026729659999999997,-1458.8282723235898 -4897,4897,S281T,-0.021101201,-0.05234161,-0.058022299000000006,-0.044012017,-0.000301299,-0.017484335,-0.005929792,-0.036272609,-0.014260803,-0.033776093,-0.070907127,-0.015541949,-0.10050264800000001,0.01182373,-0.099847763,-0.025598469,0.024995871,1.138825853,2.478525199,-1.161035834,-1.7132705380000002,-0.942879318,-0.583026443,-1.587745583,-0.978257286,-2.120028994,0.912376145,-1464.9462917619385 -4898,4898,S281W,0.066108475,-0.01622506,-0.000134965,-0.018015178,-1.05525514,-0.003238927,0.08065017599999999,0.051566772999999996,-0.030642187999999997,-0.05579145,0.02334133,-0.005308618,0.0050386879999999995,-0.054012977999999996,0.017982623,-0.818980568,-1.291529712,0.660661684,1.371834235,-6.8745367889999995,-8.565600319,-8.089257378,-4.244333984,-6.6388420560000005,-6.834650207999999,-4.720291604,-1.64615239,-1467.7945243204013 -4899,4899,S281V,0.047241332000000004,-0.021570434,0.001705484,-0.03619773,0.013298684,0.001875731,0.06246056,0.032022102999999996,0.03893919,-0.037257282,-0.005883585,0.002465779,0.0009451889999999999,-0.024586528,-0.047808932,-0.02855442,0.055151787,1.40029765,2.593260959,-2.687188548,-3.0765270539999996,-3.282566368,-1.5275307390000001,-2.800834068,-2.748484512,-2.253096128,1.501451567,-1468.5909997518174 -4900,4900,S281Y,0.03572399,-0.005337117,0.09599159800000001,0.07998810599999999,-0.098156934,0.067030042,0.012192796,0.059255184,0.049781676,-0.050046039,0.039371805,0.084652535,0.10733066,0.127903709,0.032072502,-0.095550959,-0.10076290800000001,1.298172133,2.38351553,-6.813423964,-9.667953979,-7.931272835,-4.094969162,-6.561759338,-5.811164505,-4.944999656999999,-0.782206306,-1464.8764891494066 -4901,4901,L282A,-0.0063642230000000004,-0.014422667,0.038811576,0.040555562999999996,-0.10300104199999999,-0.05789565,-0.015008345,0.0022798989999999997,0.008801646,0.0060313,-0.034876633,0.028267529,0.049355623,0.021281102000000003,0.059830022999999996,-0.094163324,-0.11183876,1.228007054,2.330854478,-6.959006015,-6.847854607,-6.365532257000001,-6.585756821,-9.919909431,-5.075976959,-1.7367670130000001,0.47515616299999996,-1464.4446135372855 -4902,4902,L282C,0.024221858,-0.025837514,0.029999442999999997,0.027600952999999998,-0.617685383,-0.048342535,0.06768610900000001,-0.019242394,-0.024250696000000002,-0.08587971900000001,0.034204691,0.020650011,0.039348874,-0.026634519,0.081836424,-0.301801852,-0.9335689140000001,1.5911561840000001,2.123610937,-9.350562146,-8.254893822,-8.907105377,-9.647688782000001,-11.06213683,-8.880985916,-5.606901799,-3.00582367,-1465.8465313217603 -4903,4903,L282E,-0.08928960400000001,-0.028858181,-0.006049179,-1.2107413759999999,-2.95431837,0.023525259,-0.053888225,-0.124690983,-0.033275574,-0.020251298,-0.037465064,0.031192466000000002,-0.043290823,-0.909849571,-1.5116331809999999,-2.7834426110000003,-3.1251941289999996,0.5104398720000001,0.734900087,-13.18431576,-13.10236191,-11.90380754,-13.29089147,-15.03427296,-12.59024492,-8.428003155,-8.955041227,-1463.5648518474773 -4904,4904,L282D,0.095681055,-0.490128511,-1.612933182,-1.888378306,-2.529507892,-0.029363657999999997,0.12046699599999999,0.07089511400000001,-0.010494479,-0.210853365,-0.769403657,-1.643502025,-1.582364339,-1.971275849,-1.805480762,-2.438328709,-2.620687074,1.314422415,0.065799607,-13.63465051,-13.40165312,-12.88160228,-13.744752300000002,-14.71708669,-13.42815817,-8.428003155,-8.955041222,-1467.0698762666434 -4905,4905,L282G,-0.008902769,-0.006361363,0.046912974,-1.146896856,-2.415650406,-0.023271938,0.028700842,-0.046506379,-0.027799141,-0.010859151000000001,-0.001863574,0.014371325,0.079454622,-0.6814828479999999,-1.6123108640000001,-2.106418595,-2.7248822169999998,1.699155243,1.344656418,-13.19512981,-12.99191829,-12.10270261,-13.56666977,-15.39203446,-11.92232394,-7.1713415220000005,-5.954071214,-1472.425558376126 -4906,4906,L282F,-0.055590161,0.0059819109999999995,0.057414232,0.004002467,-0.663794413,-0.13047984099999999,-0.054541186,-0.056639135,-0.018528412,0.01289498,-0.000931159,0.013658647,0.101169817,-0.092011034,0.10001596800000001,-0.404161934,-0.923426892,1.5756861519999998,1.971424326,-6.763994745,-6.537991333,-5.160462135,-7.389497696,-8.251776886,-6.480245674,-4.911864498,-3.1136379339999998,-1457.7806205810048 -4907,4907,L282I,-0.030712997000000002,-0.08560336800000001,0.073240526,0.014857091999999999,0.07867216,0.036917857000000005,-0.030478515,-0.030947479,0.024621081,-0.101026579,-0.070180156,0.058977284000000005,0.08750376800000001,-0.041905127,0.07161931,0.021191795,0.136152524,1.173520855,2.612980945,-0.985986638,-0.738607407,-1.457445915,-1.5558619230000001,-1.333970917,0.155952972,-1.698817496,0.121882705,-1464.76222088933 -4908,4908,L282H,-0.079556787,-0.06868542799999999,-0.665358415,-1.952067363,-3.0112685480000003,-0.00296692,-0.048420415999999994,-0.11069315800000001,-0.029361256000000002,-0.054606175,-0.08276468,-0.34075544799999996,-0.9899613820000001,-1.782472624,-2.1216621019999997,-2.8515854760000003,-3.1709516189999998,1.501122905,0.762066714,-13.62198905,-12.73985181,-12.24635916,-15.09889507,-14.53711644,-13.48772279,-8.428003155,-8.955041222,-1460.4782196218148 -4909,4909,L282K,-0.12679685699999999,0.004379624,-0.8014637990000001,-2.0804190940000002,-2.571033681,0.049597325,-0.080987092,-0.17260662100000002,0.049259315,0.04326869,-0.034509442,-0.383430637,-1.21949696,-2.225309282,-1.935528905,-2.391332146,-2.7507352160000003,1.474676645,0.655737633,-12.59331108,-12.7056953,-11.95226952,-12.99592255,-12.95067691,-12.36199111,-8.428003155,-8.955041235,-1465.6188779897057 -4910,4910,L282M,-0.011839937,-0.016202038000000002,0.129120078,0.050533957000000004,0.01266562,-0.032253916,-0.011335874,-0.012343999999999999,-0.00109089,-0.006299305,-0.026104771000000002,0.138454299,0.119785856,0.025305865,0.075762048,-0.01373452,0.03906576,1.257108315,2.684097378,-1.763789801,-2.429444473,-2.68372496,-1.717015556,-1.619271225,-0.36949279,-2.542521292,-2.3171212430000003,-1465.6729135350324 -4911,4911,L282N,-0.078977727,-0.04154513,0.019547974,-1.903827248,-2.321377818,0.032683298,-0.007880062,-0.150075392,-0.086719893,-0.021768745,-0.061321515,0.014509371,0.024586576000000002,-1.4593924880000002,-2.3482620069999998,-2.023355361,-2.619400274,1.09625668,0.750717847,-13.16298647,-13.08984703,-11.10187752,-14.15800237,-13.84783105,-13.61737439,-8.428003155,-8.955041242,-1467.590649686288 -4912,4912,L282Q,-0.084061408,-0.02514229,0.03698005,-0.013831643000000001,-1.7222842090000001,-0.03406479,-0.069408463,-0.09871435199999999,-0.044841389,0.007363813,-0.057648393,0.054368744000000004,0.019591356,0.031708728,-0.059372013,-1.6238038680000002,-1.82076455,0.624152881,1.311173159,-11.75916212,-12.45222457,-11.13783887,-11.96074274,-11.8455355,-11.3994689,-8.048662405,-7.247377752999999,-1462.2191174412146 -4913,4913,L282P,-0.041060384,-0.8257473809999999,-1.903780429,-2.180446576,-2.427915802,-0.010656915,-0.009637888,-0.07248288,0.041194232000000004,-0.600903414,-1.050591348,-2.028956322,-1.778604536,-2.228943566,-2.131949585,-2.263687516,-2.592144088,1.368162314,-0.144691753,-13.08374705,-13.0562671,-12.13835667,-13.41531433,-14.69991937,-12.10887778,-8.422041587999999,-8.92849771,-1469.3230378511362 -4914,4914,L282S,-0.011399953,-0.030331722000000002,0.066856979,0.016709488999999998,-1.65506219,-0.037299618,0.020116828,-0.042916733,-0.04014848,-0.013204324,-0.047459119,0.047250607,0.086463351,0.066552627,-0.03313365,-1.4731924330000001,-1.836931946,0.581981385,1.315810913,-11.03507537,-10.89045743,-8.511405144,-11.98425767,-12.29861272,-11.49064389,-5.557301726,-3.356527474,-1471.0646876939572 -4915,4915,L282R,-0.052282905,-0.503940882,-1.761141165,-2.017129684,-2.703589801,0.001120214,-0.029214307000000002,-0.075351503,-0.014434746000000002,-0.23265408899999998,-0.775227674,-1.825003591,-1.6972787390000001,-2.022443646,-2.011815721,-2.415710292,-2.99146931,1.109877607,-0.02789721,-12.78764478,-12.97090181,-12.07993506,-12.88355535,-13.55982487,-12.44400683,-8.428003155,-8.955041242,-1459.7760861022398 -4916,4916,L282T,-0.03096509,-0.027274398,-0.012731963999999998,0.024637596,-0.231657908,0.039189424,-0.005562998,-0.056367180999999995,0.030266843999999998,-0.05366835599999999,-0.00088044,-0.040834917000000005,0.015370989,-0.016680716,0.06595590700000001,-0.273546517,-0.18976929899999997,1.4582148209999999,2.0556633619999998,-7.676662445,-7.786269516,-5.872508904,-8.73371151,-9.227489861,-6.763332436000001,-4.402049908,-1.406968372,-1470.123770092614 -4917,4917,L282W,-0.059803572,-0.096267983,-1.344352846,-1.780907616,-2.781623897,-0.023238422999999998,-0.036687557,-0.08291958599999999,-0.049234397,-0.036756795,-0.155779171,-0.887070025,-1.801635666,-1.955206538,-1.6066086940000002,-2.723289393,-2.8399584,2.0975165319999998,0.875908585,-11.63428513,-11.64499702,-10.64677985,-11.54240542,-12.60990466,-11.72733871,-8.428003155,-8.955041236,-1451.66813941719 -4918,4918,L282V,-0.033539782000000004,-0.060183293,0.040918414,-0.014758485,-0.020573364,-0.00988052,-0.009174917,-0.057904647000000004,-0.017338213999999998,-0.036731061,-0.083635525,0.03151187,0.050324957999999996,-0.038682434,0.009165464,-0.014466388,-0.026680338999999997,1.265485044,2.416220875,-2.486444519,-2.276941559,-1.784178917,-2.882027328,-4.020611403999999,-1.468463387,-1.672163679,0.8643638709999999,-1467.3660250329413 -4919,4919,L282Y,-0.09826043300000001,-0.082840786,-0.33279512699999997,-1.633467035,-2.60798928,-0.079502726,-0.082745814,-0.113775051,-0.102314702,-0.086097144,-0.079584428,-0.086591695,-0.578998558,-1.58069694,-1.686237129,-2.445689808,-2.770288752,0.926737575,0.714213165,-12.12871137,-11.5340106,-11.29373071,-12.56489552,-12.89013869,-12.36078133,-8.428003155,-8.95504123,-1455.948651181534 -4920,4920,I283A,0.031470879,0.049791319,0.037768479,0.06238399,-0.537631351,-0.000624303,0.038498753,0.024443003999999997,0.032871686000000004,-0.09715811,0.196740747,0.018623557,0.0569134,0.031880449,0.09288753,-0.442120767,-0.633141934,0.633006162,1.441665311,-4.14370215,-6.564234894,-3.092006439,-1.638683884,-4.629826355,-4.793759178,-3.338428683,1.183837691,-1469.7689892249182 -4921,4921,I283C,0.121179051,0.107003363,0.086868051,0.14231138599999998,-0.657012279,-0.027048822,0.154521438,0.08783666400000001,0.047843912999999995,-0.05257339,0.26658011600000003,0.045003413,0.128732688,0.088204515,0.19641825699999999,-0.48642750700000004,-0.8275970509999999,0.614914715,1.421654264,-8.167929884,-10.48410428,-8.024063385,-6.232017302999999,-8.061752335,-8.03771212,-5.196253727,-2.259998438,-1464.5725144487806 -4922,4922,I283E,0.051217483,0.076399452,0.03256536,-1.0353718509999998,-2.601698129,-0.00037549999999999997,0.10060563300000001,0.0018293329999999998,-0.031887886000000004,-0.063245147,0.21604405100000001,0.016283475,0.048847244000000005,-0.538031649,-1.532712052,-2.725471013,-2.477925245,0.771546738,0.8453728770000001,-12.03870164,-14.19002785,-10.02544182,-10.71721786,-12.17702981,-13.08379086,-9.066486241,-7.600373241000001,-1469.3840968268923 -4923,4923,I283D,0.075010206,-0.255157678,-1.67594081,-1.915902265,-2.7888574889999997,-0.064807294,0.127006231,0.023014181,-0.007570611,-0.15132878800000002,-0.35898656700000003,-1.167550513,-2.184331106,-1.975068838,-1.8567356919999998,-2.637463395,-2.9402515830000002,2.479119878,1.040888058,-12.98328707,-15.05801871,-11.7931121,-11.7786171,-13.04835824,-13.23832921,-9.066486241,-7.600373241000001,-1473.8805777756497 -4924,4924,I283G,0.00841945,0.06324863900000001,0.050212600999999996,-1.074840201,-2.247811139,-0.027790242000000003,0.046688957,-0.029850058,0.012110808999999998,-0.073147911,0.199645188,0.041749982000000005,0.058675219,-0.553903814,-1.5957765869999998,-2.397469156,-2.098153122,1.5413125,1.263939184,-10.32637661,-12.43875707,-9.753404114,-8.528417503,-10.35202051,-10.55928384,-6.705257962,-4.368903826,-1475.731573753059 -4925,4925,I283F,-0.0587183,0.022810063,0.057892668,0.068766402,-0.123745791,0.03113466,0.010064407,-0.127501007,0.015709742,-0.113849663,0.159469788,0.11898656,-0.0032012240000000003,0.17761143399999998,-0.040078631,-0.12486108800000001,-0.122630494,1.226098114,2.254828956,-2.263350375,-2.091758324,-3.897251312,-2.3589753190000002,-2.041904213,-0.926862709,-2.5237125330000003,0.42777754100000004,-1467.1044193129055 -4926,4926,I283H,0.0030751159999999997,0.08844879300000001,0.080689247,0.086491254,-2.078123175,0.018155201,-0.010737295,0.016887527,-0.009880693000000001,-0.040085156000000004,0.216982741,0.059959962,0.10141853199999999,0.084568454,0.088414054,-1.74239138,-2.413854969,0.593308359,1.306097648,-11.03807585,-15.91757889,-9.080909927,-8.474869437999999,-10.66354205,-11.05347896,-6.16566191,-1.454240165,-1474.2101587201469 -4927,4927,I283K,-0.033363263,0.090361426,0.033530172000000004,-0.31869160399999996,-2.2499305769999998,0.005545774,0.022117593999999997,-0.088844119,0.026230291,-0.033819149,0.214542,0.114736719,-0.047676375,0.05473879,-0.692121998,-1.846537857,-2.653323296,0.709068722,1.304894298,-12.36120688,-14.21554958,-10.1972829,-10.70731776,-12.19367207,-14.49221211,-9.066486241,-7.600373241000001,-1471.5033364207484 -4928,4928,I283M,0.045112032999999996,0.09082645,0.073791025,0.064655477,-0.088552239,-0.081727853,0.081430124,0.008793941999999999,0.000315415,-0.030034094,0.211686994,0.064098947,0.083483103,0.013542573,0.11576838099999999,-0.157879617,-0.01922486,1.070833104,1.919357515,-4.004889311,-4.008004608,-4.000053047,-4.4612294310000005,-3.788598557,-3.766560913,-4.2179196139999995,-1.342122456,-1466.9264342039824 -4929,4929,I283L,0.059370475,0.055494218,0.060994300999999994,0.06392191400000001,-0.190349095,-0.051707737999999996,0.06646817299999999,0.05227277599999999,0.010576258,-0.118033435,0.22902187,0.027483837999999997,0.094504763,0.012760958999999999,0.115082869,-0.23469552899999999,-0.146002661,1.556426246,2.224228215,-4.005741454,-4.802651421,-4.2861185,-3.877147926,-3.141469505,-3.9213199160000003,-3.7095007439999996,-0.067305242,-1459.3633830901235 -4930,4930,I283N,-0.030648929,-0.029058431000000003,-0.09197065,-1.530969957,-2.485288831,0.034436635,0.011603071000000001,-0.072900928,-0.013120868,-0.23348127300000002,0.17536441100000003,-0.00994266,-0.17399864,-1.090462256,-1.9714776580000002,-2.354916805,-2.615660856,2.013138297,1.306079846,-11.9200045,-14.64477127,-11.35741799,-10.06872898,-11.85558034,-11.6735239,-8.13912334,-5.026295703,-1477.4900676351972 -4931,4931,I283Q,0.018505338,-0.019192578999999998,0.04345886,0.033764477,-1.9552176419999998,-0.073513621,0.026432422999999997,0.010578253000000001,0.012311433,-0.17561775899999998,0.137232601,-0.030118162999999996,0.11703588300000001,0.011300258999999998,0.056228695,-2.049034307,-1.8614009759999999,1.015707149,1.30464146,-12.30227622,-13.61869175,-10.62490625,-11.61660606,-12.22255326,-13.42862379,-8.414966215,-5.823655372,-1476.6606664396822 -4932,4932,I283P,0.031016147,0.056008005,-0.731239346,-1.76919245,-2.6138816080000002,-0.025240967000000003,0.067333854,-0.005301561,0.039669411,-0.08784305,0.19985906,-0.337616518,-1.124862174,-1.7063336130000002,-1.8320512869999999,-2.5026217490000002,-2.725141466,1.5058702919999998,0.78508746,-12.14147141,-14.02287171,-11.11407906,-10.76376951,-12.20034685,-12.6062899,-9.066486241,-7.600373241000001,-1477.2011823458597 -4933,4933,I283S,0.070348948,0.105294123,0.10049716300000001,0.10085286800000001,-1.487969518,-0.026790522999999997,0.09957900300000001,0.041118893,-0.007444504,-0.030907016000000002,0.241495262,0.087790165,0.113204161,0.101033506,0.10067223,-1.2603310559999998,-1.71560798,0.667836286,1.3329351390000002,-7.259293163,-9.757903069,-7.19049762,-5.658660697999999,-7.298424904,-6.3909795229999995,-5.004686594,-2.261343798,-1475.8824300593697 -4934,4934,I283R,0.025069288,0.075470984,0.066976878,0.071882627,-1.9482486419999998,-0.002438317,0.052025095,-0.001886519,0.027048027000000002,-0.068010175,0.218952142,0.047321063,0.086632692,0.11972595300000001,0.024039301000000003,-1.69943643,-2.197060853,0.569567267,1.30601774,-12.39829141,-12.80030426,-10.64962248,-11.28397385,-12.31113908,-14.94641736,-6.271800121,-1.858296571,-1467.065373074729 -4935,4935,I283T,0.053066206,0.06822291400000001,0.040272361,0.035321798,-0.30099536600000004,0.015663807,0.09802277400000001,0.008109638,0.034167308,-0.081143822,0.217589649,0.050691167999999995,0.029853553999999997,0.039052861,0.031590734,-0.311787741,-0.29020299,0.733911523,1.5394749269999999,-6.568960875,-7.684437492000001,-5.048252525,-5.292153702,-7.796407509,-7.023553146,-4.56979412,-1.1242438,-1472.432530859951 -4936,4936,I283W,0.01963929,0.035328206,0.030233693,0.059807255999999996,-1.71314797,-0.00078643,0.03358698,0.005691600000000001,-0.0030160559999999996,-0.095860123,0.166516535,0.029254767,0.031212617999999998,0.049099363,0.070515148,-1.186929665,-2.239366275,0.585629736,1.330068682,-9.626558827,-9.749376372999999,-10.88805367,-7.947074173,-8.848055344,-10.70023458,-5.3981691860000005,0.54274985,-1467.6002790196799 -4937,4937,I283V,0.071986976,0.068715027,0.084233081,0.056110357,-0.030749035,0.020343736,0.08410707699999999,0.059866874,0.014520176999999999,-0.058106625999999995,0.195536679,0.05498419400000001,0.113481968,0.062635996,0.049584718,-0.132006118,0.070508048,1.382819574,2.332674662,-1.719222194,-1.4818294980000002,-1.489164352,-1.661772316,-2.323498833,-1.63984597,-2.017680151,1.307049636,-1467.677767000161 -4938,4938,I283Y,-0.019137919,0.023169872,0.023007478999999997,0.067292346,-0.082166485,0.031967846,-0.058736069,0.020460232,0.158117888,-0.10256865300000001,0.148908397,0.035997653,0.010017305,0.08562900300000001,0.048955688,-0.063127466,-0.101205504,1.313105599,2.474889621,-6.397742931,-8.882764267,-7.280711273,-6.313466461,-4.687724472,-4.82404818,-4.951559262,1.652259243,-1470.2981853806414 -4939,4939,K284A,-0.0011670930000000001,-0.019496299999999998,0.011285005,0.006379218000000001,-0.038962118999999996,0.052943048,-0.032402192,0.030068006,-0.014523295,-0.032338695,-0.006653905,0.035927039,-0.013357029,0.004329126,0.008429309,-0.018958354,-0.058965884,1.671448915,3.643209181,,,,,,,,,-1462.2066247370094 -4940,4940,K284C,-0.030232923999999998,-0.007676652,-0.000796423,-0.032056912,-0.9186700179999999,0.053184482000000005,-0.026563657999999997,-0.03390219,0.026977848999999998,-0.009735615999999999,-0.005617687,0.024915488,-0.026508333999999998,-0.043491694000000004,-0.02062213,-0.554367288,-1.282972748,1.184962493,1.613005555,,,,,,,,,-1459.6289185727946 -4941,4941,K284E,-0.003045591,0.003268006,-0.013789500000000001,0.007263861999999999,-0.027480766,0.051614350999999996,-0.036752754,0.030661572,0.006596286,-0.025887765,0.032423777,-0.00867321,-0.018905789,0.035238213,-0.020710489,-0.035196934,-0.019764597,1.3568317490000001,2.646566522,,,,,,,,,-1466.227043921128 -4942,4942,K284D,0.001921604,-0.019355702,-0.009024555,0.023140319,-0.061476142000000004,0.027800756,-0.046579672999999995,0.050422880999999996,0.003573463,-0.001629866,-0.037081538,0.0055154159999999995,-0.023564526000000002,-0.0024013420000000003,0.04868198,-0.035446201000000004,-0.087506082,1.216961722,2.512366998,,,,,,,,,-1467.4754520365968 -4943,4943,K284G,0.009761721,-0.009492509,-0.0051139390000000005,-0.008522142,-0.092461612,0.032471881,-0.025707155,0.045230596,-0.008624438,-0.033617729,0.014632711999999999,0.014509484,-0.024737361,0.005783811999999999,-0.022828096000000003,-0.071991424,-0.1129318,1.196506357,2.253408402,,,,,,,,,-1466.041443687398 -4944,4944,K284F,-0.065972166,-0.034221412,-0.01915904,-0.11758794300000001,-0.286851229,-0.008126857,-0.081020365,-0.050923965999999994,0.015936925,-0.027179296000000002,-0.041263528,-0.021817568,-0.016500511000000002,-0.05743259,-0.17774329600000002,-0.204696938,-0.369005519,1.460655214,2.126313878,,,,,,,,,-1455.0879900371656 -4945,4945,K284I,-0.047915060999999995,-0.004677264,0.008121187,0.007687492,-0.514835422,0.032596239,-0.056873817,-0.038956305,-0.056263645999999994,0.089189688,-0.09854421599999999,0.114206104,-0.097963731,0.069152347,-0.053777364,-0.217600885,-0.812069959,1.017217977,1.8426262409999998,,,,,,,,,-1459.7693995833397 -4946,4946,K284H,-0.027958999,0.013219203,0.042184872000000005,0.01037147,-0.005217661,0.028335074,-0.058262130999999995,0.002344133,-0.026491815,-0.01062156,0.037059966,0.079750958,0.004618786,0.025085209,-0.004342269,0.016745608999999998,-0.02718093,1.200113388,2.611282903,,,,,,,,,-1458.7059536143206 -4947,4947,K284M,0.039465525,-0.018350618,-0.032598517,-0.052190732000000004,-0.107795746,-0.0037128659999999996,0.004173865,0.074757184,-0.032671043,-0.058862659000000005,0.022161424,-0.045925834000000006,-0.019271199,-0.064225399,-0.040156065,-0.096675394,-0.118916097,1.369948383,2.282464032,,,,,,,,,-1459.2942271628417 -4948,4948,K284L,-0.030876035,-0.005206454,0.004979038,0.000922447,-0.044259464000000005,0.051762104,-0.064098921,0.002346851,-0.00201594,0.000140074,-0.010552981000000001,0.012523693,-0.002565618,0.016421316000000002,-0.014576423,-0.051654697,-0.03686423,1.4037943080000002,2.51319102,,,,,,,,,-1457.4396438556723 -4949,4949,K284N,-0.005976686,-0.054977825999999994,-0.017956623,-0.063212299,-0.074528787,-0.011069381000000001,-0.032354044,0.020400671999999998,0.007503757,-0.078676345,-0.031279307,-0.024302534,-0.011610711999999999,-0.06775838,-0.058666218,-0.11145271,-0.037604862999999995,1.279133157,2.119113416,,,,,,,,,-1464.2794307675213 -4950,4950,K284Q,0.0032249559999999997,-0.036001727000000004,-0.048279694000000005,-0.0067570830000000005,-0.071555783,0.049682372,-0.037211358,0.043661269,-0.00904615,-0.067012131,-0.004991322,-0.071459227,-0.025100161,-0.053629752,0.040115587,-0.105303744,-0.037807822000000005,1.61037071,2.4644736000000003,,,,,,,,,-1462.4966960549355 -4951,4951,K284P,-0.039515673,-0.0026040620000000003,-0.199204388,-1.59051964,-2.593265847,0.032548807,-0.051037427,-0.027993918,-0.039058728,-0.015559469,0.010351345999999999,-0.04020411,-0.358204666,-1.312285352,-1.868753928,-2.3761040980000003,-2.8104275960000002,0.959654553,0.748398298,,,,,,,,,-1468.570735768415 -4952,4952,K284S,0.019029421,0.010499555,0.0033442059999999997,0.016708824,-0.020231824,0.035576829,-0.018134999,0.056193840999999994,-0.006438312,0.00108266,0.01991645,0.027294527000000002,-0.020606115,0.04676759900000001,-0.013349951,-0.027272464,-0.013191183,1.380401521,2.613084933,,,,,,,,,-1462.8641392523423 -4953,4953,K284R,0.029148916,0.009022216999999999,0.004103836,0.017886226,-0.041719978,0.019733564,-0.014501422,0.07279925400000001,-0.00243367,0.021426346000000002,-0.003381912,0.041838686,-0.033631014,0.059935774000000004,-0.024163322,-0.019150975,-0.064288981,1.1306588690000001,2.487209058,,,,,,,,,-1459.1308416370302 -4954,4954,K284T,-0.012975183000000001,-0.023907811,-0.012975258,-0.042232717999999995,-0.090440961,0.029528653,-0.037955704,0.012005338,-0.000845933,-0.03806444,-0.009751181999999999,-0.022809471,-0.0031410440000000004,-0.015327313,-0.069138122,-0.082459895,-0.098422027,1.281367367,2.270237021,,,,,,,,,-1463.0540440459736 -4955,4955,K284W,-0.016195725,0.00863963,0.0036231659999999997,-0.021032951,-0.44988467299999996,0.04982133,-0.062543173,0.030151723,-0.007421921,-0.008298999,0.025578259,0.016236738,-0.008990406999999999,-0.00421365,-0.037852251,-0.31281458300000003,-0.5869547629999999,1.145886887,1.77664944,,,,,,,,,-1457.563735825941 -4956,4956,K284V,-0.027768052999999997,0.0020763820000000003,-0.00975478,0.012846875,-0.26129694800000003,0.014595058999999999,-0.049508061,-0.006028045,0.043468785,0.023254405,-0.019101642,0.017752773,-0.037262332999999995,0.024574407000000003,0.001119342,-0.176720362,-0.34587353299999996,1.42533513,2.198468251,,,,,,,,,-1461.037082365714 -4957,4957,K284Y,-0.00451025,-0.011810131000000001,0.023828214,0.011551488,-0.11147226199999999,-0.016285368999999997,-0.030725517,0.021705018,-0.011562315,-0.010912193999999998,-0.012708067,0.032238096,0.015418331,0.008925313,0.014177661999999999,-0.083951464,-0.13899306,1.253507871,2.257540566,,,,,,,,,-1455.2370101725683 -4958,4958,H285A,-0.046267157,-0.052390898,0.012269418999999998,-0.04571516900000001,-0.465274388,0.080088467,-0.040147017,-0.05238729599999999,-0.064010873,-0.048071382999999995,-0.056710412,0.002874559,0.021664278999999998,-0.023498758999999998,-0.06793157799999999,-0.306232018,-0.624316758,1.3365430040000001,1.902832985,,,,,,,,,-1459.3983200080693 -4959,4959,H285C,-0.027152107999999998,-0.07850001,-0.082541639,-0.060775824000000006,-0.251095353,0.079985056,-0.027705358,-0.026598858,-0.124907305,0.010243541,-0.16724356099999999,-0.114337169,-0.050746108,-0.025817866000000002,-0.09573378199999999,-0.14693134900000002,-0.355259356,1.550802741,2.320464894,,,,,,,,,-1462.392365803942 -4960,4960,H285E,-0.04668786,-0.077489954,-0.057370818,-0.083205007,-0.33876170899999997,-0.011353925,-0.017635662,-0.075740057,-0.026848862999999997,-0.049955342,-0.105024566,-0.044883499,-0.069858136,-0.056825172,-0.109584841,-0.262738058,-0.41478535899999996,1.200128361,1.874139605,,,,,,,,,-1461.148920595646 -4961,4961,H285D,-0.064282928,-0.082233998,-0.027357107000000002,-0.025369133999999998,-1.535460946,0.121029753,-0.047387509,-0.081178346,-0.098661203,-0.017597391,-0.146870605,-0.008108886,-0.046605327,-0.00703111,-0.043707157999999996,-1.223209889,-1.847712002,0.584649467,1.328290672,,,,,,,,,-1465.877538538538 -4962,4962,H285G,-0.03437017,-0.034153432000000004,-0.013024638,-0.02675492,-0.50993699,0.090507129,-0.022940508,-0.045799832,-0.067304919,-0.021596973999999998,-0.046709889000000004,0.00076758,-0.026816855,-0.024677812,-0.028832027000000003,-0.280781037,-0.739092942,1.107088895,1.743985783,,,,,,,,,-1461.605618007481 -4963,4963,H285F,0.006117895999999999,-0.036883347000000004,-0.024579855,-0.048331434000000006,-0.149276371,0.11128691800000001,0.071738573,-0.059502781,0.024400852999999997,-0.06656580200000001,-0.007200891,-0.05094427,0.00178456,-0.057803082,-0.038859785,-0.08654172199999999,-0.21201102,1.573480749,2.526964858,,,,,,,,,-1462.843289327342 -4964,4964,H285I,-0.052110944000000006,-0.108262475,-0.016498274,-1.23904755,-2.723116824,-0.004294424,-0.016216063,-0.08800582400000001,-0.059604628,-0.12248882300000001,-0.094036127,-0.051102167000000004,0.018105619,-0.9004265029999999,-1.577668597,-2.759185255,-2.687048392,1.03424844,0.831650997,,,,,,,,,-1466.6967925410718 -4965,4965,H285K,-0.029627248999999998,-0.009882353,-0.03269644,-0.050791848,-0.271887231,0.015611008000000001,-0.024860776,-0.034393721,-0.109009218,0.011815511,-0.031580216,0.01232229,-0.07771517,-0.012094987,-0.089488709,-0.165372451,-0.37840201,1.158000938,1.952331174,,,,,,,,,-1453.4025540933944 -4966,4966,H285M,-0.081040735,-0.036226921,-0.015397395,-0.065995181,-0.226841047,0.04186132,-0.070107086,-0.091974384,-0.028012836,0.014937559,-0.0873914,0.022134445,-0.052929235,-0.04576579,-0.086224571,-0.10025776300000001,-0.35342433,1.4537318940000001,2.363739969,,,,,,,,,-1463.5122858942486 -4967,4967,H285L,-0.069336279,-0.035497166000000004,-0.02413953,-0.029208635,-0.553995627,0.077208835,-0.043290227,-0.095382331,-0.058612122999999995,-0.020165842,-0.050828489000000004,-0.0013067110000000001,-0.046972349000000004,-0.022405495,-0.036011773999999996,-0.376965626,-0.7310256270000001,1.060233778,1.654608708,,,,,,,,,-1464.5801092120819 -4968,4968,H285N,0.021839973,0.038751369,-0.005295227,-0.04368690099999999,0.024088321,0.06034565,0.027459507,0.016220438,-0.075757703,0.031753077000000005,0.04574966,0.0039702159999999995,-0.014560668999999998,0.012393161000000001,-0.09976696300000001,0.067893098,-0.019716456,1.155290124,2.8654402830000003,,,,,,,,,-1461.2774336994626 -4969,4969,H285Q,-0.029835568,0.0033283370000000002,0.057769555,0.013336226000000001,-0.141955412,0.037134086000000004,-0.024020299,-0.035650836,-0.03393331,0.033311942000000004,-0.026655268,0.11306170199999999,0.002477407,0.101224588,-0.074552137,-0.1049178,-0.178993023,1.334330892,2.545821853,,,,,,,,,-1462.0701953694224 -4970,4970,H285P,-0.079973704,-0.054928174,-0.9141689740000001,-2.113696092,-2.724870193,0.067835534,-0.051419377,-0.108528031,-0.061057115999999995,-0.045898840999999996,-0.063957506,-0.450210971,-1.378126977,-1.901475477,-2.3259167069999998,-2.76323974,-2.6865006460000003,1.6162079719999998,0.7604078009999999,,,,,,,,,-1463.9308109171689 -4971,4971,H285S,-0.042936010999999996,-0.056729840999999996,-0.018897727,-0.019913888,-0.160348785,0.075993374,-0.020595921,-0.065276101,-0.07262481700000001,-0.041467078,-0.071992604,-0.015794267,-0.022001186000000002,0.00694886,-0.046776635999999996,-0.094238832,-0.22645873800000002,1.314890865,2.2801780590000003,,,,,,,,,-1460.1830080985092 -4972,4972,H285R,-0.04849393900000001,-0.019034863,-0.017791108,-0.029604352,-0.157191089,0.061143002,-0.037726471,-0.059261405999999996,-0.079473611,0.0037703809999999997,-0.041840107,0.00179255,-0.037374766000000004,-0.014884838000000001,-0.044323865,-0.112055885,-0.202326292,1.4004578840000002,2.288350094,,,,,,,,,-1454.7754900413565 -4973,4973,H285T,-0.055620389000000006,-0.043969707999999996,-0.044884067,-0.054940351,-0.113390602,0.063022922,-0.055436848,-0.05580393,-0.090678626,-0.026670265,-0.061269150999999994,0.0039702159999999995,-0.093738349,-0.030304888999999998,-0.079575812,-0.072089658,-0.154691545,1.514346548,2.541142889,,,,,,,,,-1461.2131763291545 -4974,4974,H285W,-0.055681479000000006,-0.032883943,-0.014249615,-0.054198737999999996,-0.076231453,0.072687403,-0.062485639,-0.048877317999999996,-0.078175787,0.012021458999999998,-0.07778934400000001,-0.015664917,-0.012834311999999999,-0.020387266,-0.088010209,-0.008240715,-0.144222191,1.30233762,2.631740956,,,,,,,,,-1462.9209620500915 -4975,4975,H285V,-0.038604749,-0.021556971,-0.025822966,-0.038819881,-0.8257314490000001,0.084401481,-0.04825374599999999,-0.028955752,-0.02222136,-0.021360147000000003,-0.021753794,0.007942071,-0.059588003,-0.030127387000000002,-0.047512375,-0.483575343,-1.167887555,1.2029670890000002,1.665454901,,,,,,,,,-1466.5294512528926 -4976,4976,H285Y,-0.072056969,-0.041721957999999996,-0.08357903700000001,-0.031318184,-0.09468585300000001,0.050036400999999994,-0.055260606,-0.088853331,-0.023220672999999997,-0.022343827,-0.061100088,-0.08003516299999999,-0.08712291,-0.046817004,-0.015819363,-0.0750808,-0.114290905,1.374097325,2.326613476,,,,,,,,,-1460.1731320056133 -4977,4977,W286A,-0.03794522,-0.322941308,-1.787981671,-1.9614080230000002,-3.1787981039999997,0.076148022,-0.022854452999999997,-0.053035987,-0.026969418999999998,-0.13907507300000002,-0.506807543,-1.534465091,-2.04149825,-1.9525549119999999,-1.970261134,-3.037843642,-3.3197525660000005,2.656269194,1.056615656,,,,,,,,,-1461.1493681077845 -4978,4978,W286C,-0.044844145,-0.313323858,-1.7240013459999999,-2.096397703,-2.983761815,0.059320785,0.012885923999999998,-0.102574214,-0.0321029,-0.06455608,-0.562091636,-1.608498837,-1.839503855,-1.880460623,-2.3123347830000003,-2.907757405,-3.0597662239999996,2.757086174,1.145064317,,,,,,,,,-1456.9484017211944 -4979,4979,W286E,-0.060069761,-0.034149636000000004,-0.706144653,-1.904946112,-2.545852462,0.044144947000000004,-0.014809628,-0.10532989300000001,-0.069830349,-0.027899284,-0.040399987000000005,-0.321592411,-1.090696895,-1.7934588980000001,-2.016433325,-2.238899075,-2.8528058489999997,1.4850155369999998,0.7610148940000001,,,,,,,,,-1458.4000591039658 -4980,4980,W286D,-0.098225732,-0.092319389,-0.991545637,-2.162412268,-2.859106006,0.027078649,-0.048379415999999995,-0.148072048,-0.017223036,-0.096065304,-0.088573474,-0.476826718,-1.5062645559999999,-1.9918265519999998,-2.332997984,-2.47505529,-3.2431567219999997,1.632738385,0.734380347,,,,,,,,,-1458.91911783861 -4981,4981,W286G,-0.020285201,-0.023080383,-1.0494353159999998,-2.035040286,-3.228429174,0.060527429,0.011754573999999999,-0.052324975999999995,-0.042765965999999996,-0.046775209000000005,0.000614444,-0.654189172,-1.4446814590000001,-1.879770376,-2.190310196,-2.474149566,-3.982708782,1.933994225,0.8605398390000001,,,,,,,,,-1460.0210760105401 -4982,4982,W286F,-0.039678789,0.022006698999999998,-0.05139122,-0.035329727000000005,-0.780425279,0.029596279,-0.008837059,-0.070520519,-0.045872715999999994,0.023657577000000003,0.02035582,-0.049465695999999997,-0.053316743,-0.028385327999999998,-0.042274125,-0.414184251,-1.146666306,1.155829645,1.677639804,,,,,,,,,-1462.2606241218746 -4983,4983,W286I,-0.079611889,-0.002497151,-0.001055027,-1.204237153,-2.429502334,0.060793225,-0.03499656,-0.12422721699999999,-0.042629379,-0.045114732000000005,0.04012043,-0.007004702,0.004894649,-0.63365367,-1.774820635,-2.0771152809999998,-2.781889386,1.699155243,1.344656418,,,,,,,,,-1462.9744099653326 -4984,4984,W286H,-0.123809877,-0.05872987599999999,-0.039697843999999996,-0.9666943590000001,-1.782739799,-0.008238344,-0.106133802,-0.141485951,-0.04853213,-0.009241173,-0.10821857800000001,-0.016999718,-0.062395969,-0.40166578399999997,-1.531722934,-1.8769255919999999,-1.688554006,1.566215457,1.38598284,,,,,,,,,-1458.7067998782732 -4985,4985,W286K,-0.024663504,-0.036908803999999996,-0.8407895879999999,-1.817969863,-2.566351628,0.00249217,0.038081734,-0.087408741,-0.110334137,-0.11976654800000001,0.04594894,-0.505116357,-1.176462818,-1.891021495,-1.74491823,-2.918318277,-2.214384979,1.742588391,0.792661469,,,,,,,,,-1455.6285570310429 -4986,4986,W286M,-0.070083197,-0.026072183,-0.049894945999999996,0.010723905,-1.6997812630000002,-0.042759615,-0.036310236,-0.10385615699999999,-0.032656403,0.011282621000000001,-0.063426987,-0.01722688,-0.08256301099999999,0.056412628,-0.034964819,-1.576971635,-1.82259089,0.6128761979999999,1.312323321,,,,,,,,,-1466.9283759552054 -4987,4987,W286L,-0.056208465,-0.026258346000000002,-0.043624029,-1.299020745,-2.244688275,0.015539315,-0.022969213,-0.089447716,-0.027575447000000003,-0.025643951,-0.026872741000000002,-0.017836169,-0.069411888,-0.771829807,-1.8262116819999998,-2.150946137,-2.3384304119999997,1.910193482,1.3923981019999998,,,,,,,,,-1464.4048153464682 -4988,4988,W286N,-0.009794482,-0.054397613,-0.264041511,-1.887312939,-2.584006677,0.00829173,0.050642488,-0.070231451,-0.111642845,-0.087972897,-0.020822329,-0.150411309,-0.37767171299999996,-1.9254825309999999,-1.849143346,-2.408711269,-2.7593020839999998,1.039487314,0.6816141170000001,,,,,,,,,-1459.3984346552752 -4989,4989,W286Q,-0.051180388,-0.067660309,-0.263159765,-1.6721096709999999,-2.699394131,-0.042502924000000004,-0.024774867000000002,-0.07758590900000001,-0.058757725,-0.064868185,-0.070452432,-0.148447114,-0.377872415,-1.297221353,-2.046997988,-2.043691526,-3.355096735,2.656661711,1.752924673,,,,,,,,,-1459.8793342732824 -4990,4990,W286P,-0.020773802,-0.032204064,-0.6790091979999999,-1.774133056,-2.793520382,0.027337507,0.020801137,-0.06234874,-0.046381871,-0.052928428,-0.011479699,-0.244191035,-1.11382736,-1.6278887290000001,-1.9203773819999999,-2.550450161,-3.036590602,1.295336592,0.7582032409999999,,,,,,,,,-1457.0694072255865 -4991,4991,W286S,-0.035005545,-0.110906583,-1.368383906,-2.347502246,-2.967712254,0.049699476,0.0037133979999999997,-0.073724487,-0.06176882400000001,-0.024788285,-0.197024881,-1.037578575,-1.699189236,-2.405870928,-2.289133564,-2.463130933,-3.4722935739999996,0.891281326,0.140268785,,,,,,,,,-1459.1793474806473 -4992,4992,W286R,-0.025876952999999998,-0.012934593000000001,-0.853983933,-1.902060668,-2.7077312589999996,0.021912026,0.006036589,-0.057790495,-0.080176346,-0.039498408,0.013629222,-0.366959649,-1.341008217,-1.8013862669999998,-2.0027350680000002,-2.381525018,-3.033937499,1.49838426,0.7607122070000001,,,,,,,,,-1455.6414524377324 -4993,4993,W286T,-0.072448841,-0.120705141,-1.316637014,-2.070245121,-2.8064217439999997,0.046943739000000005,-0.00630607,-0.138591611,-0.074702488,-0.012398127,-0.229012154,-1.0228292620000001,-1.6104447659999999,-1.9290357219999998,-2.211454519,-2.3800797769999997,-3.23276371,3.111094417,1.695993707,,,,,,,,,-1461.3904218440875 -4994,4994,W286V,-0.015917203,-0.03684768,-0.943010715,-1.866516117,-2.813837323,0.02721362,0.029899297999999998,-0.061733704,-0.038513113,-0.039365157000000005,-0.034330203,-0.524840289,-1.3611811409999999,-1.8179913730000001,-1.915040861,-2.535303317,-3.092371328,1.76202265,0.824707313,,,,,,,,,-1463.4804986952804 -4995,4995,W286Y,-0.05769650900000001,-0.051533859,-0.03460837,-0.043875017,-0.9623609540000001,0.06759620599999999,-0.019271041000000003,-0.096121977,0.02454355,-0.016550427,-0.086517291,0.006978828,-0.076195567,-0.085645488,-0.002104546,-0.681236407,-1.2434855009999999,1.283680001,1.601609905,,,,,,,,,-1460.9960768222809 diff --git a/esm/variant-prediction/predict.py b/esm/variant-prediction/predict.py deleted file mode 100644 index b0ba7a5..0000000 --- a/esm/variant-prediction/predict.py +++ /dev/null @@ -1,249 +0,0 @@ -# Copyright (c) Facebook, Inc. and its affiliates. -# -# This source code is licensed under the MIT license found in the -# LICENSE file in the root directory of this source tree. - -import argparse -import itertools -import pathlib -from typing import List, Tuple - -import pandas as pd -import torch -from Bio import SeqIO -from tqdm import tqdm - -from esm import (Alphabet, FastaBatchedDataset, MSATransformer, - ProteinBertModel, pretrained) - - -def read_msa(filename: str, nseq: int) -> List[Tuple[str, str]]: - """Reads the first nseq sequences from an MSA file, automatically removes insertions.""" - - msa = [ - (record.description, str(record.seq)) - for record in itertools.islice(SeqIO.parse(filename, "fasta"), nseq) - ] - msa = [(desc, seq.upper()) for desc, seq in msa] - return msa - - -def create_parser(): - parser = argparse.ArgumentParser( - description="Label a deep mutational scan with predictions from an ensemble of ESM-1v models." # noqa - ) - - # fmt: off - parser.add_argument( - "--model-location", - type=str, - help="PyTorch model file OR name of pretrained model to download (see README for models)", - nargs="+", - ) - parser.add_argument( - "--sequence", - type=str, - help="Base sequence to which mutations were applied", - ) - parser.add_argument( - "--dms-input", - type=pathlib.Path, - help="CSV file containing the deep mutational scan", - ) - parser.add_argument( - "--mutation-col", - type=str, - default="mutant", - help="column in the deep mutational scan labeling the mutation as 'AiB'" - ) - parser.add_argument( - "--dms-output", - type=pathlib.Path, - help="Output file containing the deep mutational scan along with predictions", - ) - parser.add_argument( - "--offset-idx", - type=int, - default=0, - help="Offset of the mutation positions in `--mutation-col`" - ) - parser.add_argument( - "--scoring-strategy", - type=str, - default="wt-marginals", - choices=["wt-marginals", "pseudo-ppl", "masked-marginals"], - help="" - ) - parser.add_argument( - "--msa-path", - type=pathlib.Path, - help="path to MSA (required for MSA Transformer)" - ) - parser.add_argument( - "--msa-samples", - type=int, - default=400, - help="number of sequences to randomly sample from the MSA" - ) - # fmt: on - parser.add_argument( - "--nogpu", action="store_true", help="Do not use GPU even if available" - ) - return parser - - -def label_row(row, sequence, token_probs, alphabet, offset_idx): - wt, idx, mt = row[0], int(row[1:-1]) - offset_idx, row[-1] - assert ( - sequence[idx] == wt - ), "The listed wildtype does not match the provided sequence" - - wt_encoded, mt_encoded = alphabet.get_idx(wt), alphabet.get_idx(mt) - - # add 1 for BOS - score = token_probs[0, 1 + idx, mt_encoded] - token_probs[0, 1 + idx, wt_encoded] - return score.item() - - -def compute_pppl(row, sequence, model, alphabet, offset_idx): - wt, idx, mt = row[0], int(row[1:-1]) - offset_idx, row[-1] - assert ( - sequence[idx] == wt - ), "The listed wildtype does not match the provided sequence" - - # modify the sequence - sequence = sequence[:idx] + mt + sequence[(idx + 1) :] - - # encode the sequence - data = [ - ("protein1", sequence), - ] - - batch_converter = alphabet.get_batch_converter() - - batch_labels, batch_strs, batch_tokens = batch_converter(data) - - wt_encoded, mt_encoded = alphabet.get_idx(wt), alphabet.get_idx(mt) - - # compute probabilities at each position - log_probs = [] - for i in range(1, len(sequence) - 1): - batch_tokens_masked = batch_tokens.clone() - batch_tokens_masked[0, i] = alphabet.mask_idx - with torch.no_grad(): - token_probs = torch.log_softmax( - model(batch_tokens_masked.cuda())["logits"], dim=-1 - ) - log_probs.append( - token_probs[0, i, alphabet.get_idx(sequence[i])].item() - ) # vocab size - return sum(log_probs) - - -def main(args): - # Load the deep mutational scan - df = pd.read_csv(args.dms_input) - - # inference for each model - for model_location in args.model_location: - model, alphabet = pretrained.load_model_and_alphabet(model_location) - model.eval() - if torch.cuda.is_available() and not args.nogpu: - model = model.cuda() - print("Transferred model to GPU") - - batch_converter = alphabet.get_batch_converter() - - if isinstance(model, MSATransformer): - data = [read_msa(args.msa_path, args.msa_samples)] - assert ( - args.scoring_strategy == "masked-marginals" - ), "MSA Transformer only supports masked marginal strategy" - - batch_labels, batch_strs, batch_tokens = batch_converter(data) - - all_token_probs = [] - for i in tqdm(range(batch_tokens.size(2))): - batch_tokens_masked = batch_tokens.clone() - batch_tokens_masked[ - 0, 0, i - ] = alphabet.mask_idx # mask out first sequence - with torch.no_grad(): - token_probs = torch.log_softmax( - model(batch_tokens_masked.cuda())["logits"], dim=-1 - ) - all_token_probs.append(token_probs[:, 0, i]) # vocab size - token_probs = torch.cat(all_token_probs, dim=0).unsqueeze(0) - df[model_location] = df.apply( - lambda row: label_row( - row[args.mutation_col], - args.sequence, - token_probs, - alphabet, - args.offset_idx, - ), - axis=1, - ) - - else: - data = [ - ("protein1", args.sequence), - ] - batch_labels, batch_strs, batch_tokens = batch_converter(data) - - if args.scoring_strategy == "wt-marginals": - with torch.no_grad(): - token_probs = torch.log_softmax( - model(batch_tokens.cuda())["logits"], dim=-1 - ) - df[model_location] = df.apply( - lambda row: label_row( - row[args.mutation_col], - args.sequence, - token_probs, - alphabet, - args.offset_idx, - ), - axis=1, - ) - elif args.scoring_strategy == "masked-marginals": - all_token_probs = [] - for i in tqdm(range(batch_tokens.size(1))): - batch_tokens_masked = batch_tokens.clone() - batch_tokens_masked[0, i] = alphabet.mask_idx - with torch.no_grad(): - token_probs = torch.log_softmax( - model(batch_tokens_masked.cuda())["logits"], dim=-1 - ) - all_token_probs.append(token_probs[:, i]) # vocab size - token_probs = torch.cat(all_token_probs, dim=0).unsqueeze(0) - df[model_location] = df.apply( - lambda row: label_row( - row[args.mutation_col], - args.sequence, - token_probs, - alphabet, - args.offset_idx, - ), - axis=1, - ) - elif args.scoring_strategy == "pseudo-ppl": - tqdm.pandas() - df[model_location] = df.progress_apply( - lambda row: compute_pppl( - row[args.mutation_col], - args.sequence, - model, - alphabet, - args.offset_idx, - ), - axis=1, - ) - - df.to_csv(args.dms_output) - - -if __name__ == "__main__": - parser = create_parser() - args = parser.parse_args() - main(args) From 112da34e94baa6dd84ab4d06e4fabe5a70e65e4c Mon Sep 17 00:00:00 2001 From: Carlo Fisicaro Date: Fri, 27 May 2022 12:31:30 +0200 Subject: [PATCH 2/3] feat: esm submodule --- .gitmodules | 3 +++ esm | 1 + 2 files changed, 4 insertions(+) create mode 100644 .gitmodules create mode 160000 esm diff --git a/.gitmodules b/.gitmodules new file mode 100644 index 0000000..5b7ec54 --- /dev/null +++ b/.gitmodules @@ -0,0 +1,3 @@ +[submodule "esm"] + path = esm + url = https://github.com/facebookresearch/esm diff --git a/esm b/esm new file mode 160000 index 0000000..138f279 --- /dev/null +++ b/esm @@ -0,0 +1 @@ +Subproject commit 138f279c1295c9132fd3d470057cdcf49b448dce From 1b61f12b16f9c24aa71165e232fe5b5848f5b0f2 Mon Sep 17 00:00:00 2001 From: Carlo Fisicaro Date: Fri, 27 May 2022 12:35:36 +0200 Subject: [PATCH 3/3] feat: new embedding extract script path --- adopt/embedding.py | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/adopt/embedding.py b/adopt/embedding.py index 12c607b..a766b08 100644 --- a/adopt/embedding.py +++ b/adopt/embedding.py @@ -50,7 +50,7 @@ def get_representations(fasta_file, repr_dir, msa): ) else: bashCommand = ( - "python esm/extract.py " + "python esm/scripts/extract.py " + str(esm_model) + " " + str(fasta_file)